[ { "cls_id": "homologset.oma.809876", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2Q5-1", "uniprot_id": "Q5U2Q5_RAT", "id": "Q5U2Q5-1", "name": "Ribonucleoside-diphosphate reductase", "aln": "---------------MHVIKRDGRQERVMFDKITSRIQKLCYG---LNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGRHSPMVASSTLEIVMAHKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLSEKWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYESYEKQ-GRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTP--------EHTYDFEKLAEVTKVIVRNLNKIIDINYYPIPEAHLSNKRHRPIGIGVQGLADAFILMRYPFESPEAQLLNKQIFETIYYGALEASCDLAKEYGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKLLKEKIAKYG-IRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWNEEMKNQIIACNGSIQSIPEIPEDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLN-------------------------------------KEK-------LKDKEKAL------------------------------------KEEEEKERNTAAMVCSLE------------NREECLMCGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07742-1", "uniprot_id": "RIR1_MOUSE", "id": "P07742-1", "name": "Ribonucleoside-diphosphate reductase large subunit", "aln": "---------------MHVIKRDGRQERVMFDKITSRIQKLCYG---LNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGRHSPMVASSTLDIVMANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLSEKWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYESYEKQ-GRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTP--------EHTYDFEKLAEVTKVIVRNLNKIIDINYYPIPEAHLSNKRHRPIGIGVQGLADAFILMRYPFESPEAQLLNKQIFETIYYGALEASCELAKEYGPYETYEGSPVSKGILQYDMWNVAPTDLWDWKPLKEKIAKYG-IRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWNEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLN-------------------------------------KEK-------LKDKEKAL------------------------------------KEEEEKERNTAAMVCSLE------------NREECLMCGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3I3B7-1", "uniprot_id": "G3I3B7_CRIGR", "id": "G3I3B7-1", "name": "Ribonucleoside-diphosphate reductase", "aln": "---------------MHVIKRDGRQERVMFDKITSRIQKLCYG---LNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLHNYINPHNGRHSPMVASSTLDIVMANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLSEKWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYESYEKQ-GRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTP--------EHTYDFQKLAEVTKVIVRNLNKIIDINYYPIPEAHLSNKRHRPIGIGVQGLADAFILMRYPFESPEAQLLNKQIFETIYYGALEASCDLAKEYGPYETYEGSPVSKGILQYDMWNVVPTDLWDWKLLKEKIAKYG-VRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWNEEMKNQIIACNGSIQSISEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLN-------------------------------------KEK-------LKDREKAL------------------------------------KEEEEKERNTAAMVCSLE------------NREECLMCGS", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "A0A287A8J7-1", "uniprot_id": "A0A287A8J7_PIG", "id": "A0A287A8J7-1", "name": "Ribonucleoside-diphosphate reductase", "aln": "---------------MHVIKRDGRQERVMFDKITSRIQKLCYG---LNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLFNYINPHNGKHSPMVAS-TLDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKISGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLSEKWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYESYERQ-GHVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTS--------EHTYDFTKLAEVTKVIVRNLNKIIDINYYPIPEASLSNKRHRPIGIGVQGLADAFILMRYPFESPEAQLLNKQIFETIYYGALEASCDLAKEYGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKLLKEKIAKYG-IRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWNEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLN-------------------------------------KEK-------LKDKEKVS------------------------------------KEEE-KERNTAAMVCSLE------------NRDECLMCGS", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "F1MSF1-1", "uniprot_id": "F1MSF1_BOVIN", "id": "F1MSF1-1", "name": "Ribonucleoside-diphosphate reductase", "aln": "---------------MHVIKRDGRQERVMFDKITSRIQKLCYG---LNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLFNYINPHNGKHSPMVAKSTLDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLSEKWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYERYEKE-GRVRKVIKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTS--------EHTYDFTKLAEVTKVIVRNLNKIIDINYYPVPEASLSNKLHRPIGIGVQGLADAFILMRYPFESPEAQLLNKQIFETIYYGALEASCDLAKEYGPYETYEGSPVSKGILQYDMWNVTPTDLWDWNLLKEKIAKYG-VRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWNEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLN-------------------------------------KEK-------LKDKEKVS------------------------------------KEEE-KERNTAAMVCSLE------------NRDECLMCGS", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "P23921-1", "uniprot_id": "RIR1_HUMAN", "id": "P23921-1", "name": "Ribonucleoside-diphosphate reductase large subunit", "aln": "---------------MHVIKRDGRQERVMFDKITSRIQKLCYG---LNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKSTLDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYASYEKQ-GRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTS--------EHTYDFKKLAEVTKVVVRNLNKIIDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYG-IRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLN-------------------------------------KEK-------LKDKEKVS------------------------------------KEEEEKERNTAAMVCSLE------------NRDECLMCGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P79732-1", "uniprot_id": "RIR1_DANRE", "id": "P79732-1", "name": "Ribonucleoside-diphosphate reductase large subunit", "aln": "---------------MHVIKRDGGQEGVMFDKITSRIQKLCYG---LNSDFVDPTQITMKVIQGLYSGVTTVELDTLAAETAATSTTKHPDYAILAARIAVSNLHKETKKVFSEVMEDLYNYVNPLNSRHSPMISKETLDIVLANKDRLNSAIIYDRDFSYNFFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIAAAIETYNLLSEKWFTHASPTLFNAGTNRPQLSSCFLLAMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGRYIAGTNGNSNGLVPMLRVNNNTARYVDQGGNKRPGAFAMYLEPWHFDIFDFLELKKNTGKEEQRARDLFYALWIPDLFMKRVETNGDWSLMCPNDCPGLDECWGEEFEKLYAKYEQE-GRAKRVVKAQQLWYAIIESQTETGTPYMLYKDACNRKSNRQNLGTIKCSNLCTEIVEYTSADEVAVCNLASIALNMYVTS--------ERTFDFQKLASVTKVIVKNLNKIIDINYYPVKEAENSNKRHRPIGIGVQGLADAFILMRFPFESTEAQLLNTQIFETIYYAALESSCELAAEYGPYQTYAGCPVSKGILQYDMWEKTPTDLWDWAALKEKIANDG-VRNSLLLAPMPTASTAQILGNNESIEPYTSNIYHRRVLSGEFQIVNPHLLKDLTERGLWNEEMKNQIIAQNGSIQTIPAIPDDLKELYKTVWEISQKTILKMAADRGAYIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTKPGANPIQFTLN-------------------------------------KEK-------LKETQKTTS----------------------------------SEDEETKERNKAAMVCSLE------------NRHECLMCGS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48591-1", "uniprot_id": "RIR1_DROME", "id": "P48591-1", "name": "Ribonucleoside-diphosphate reductase large subunit", "aln": "----MLKNKSMKTSKLYVIKRDGRQEEVHFDKITSRIQKLCYN---LNMDFVDPVTITLQVINGLYCGVTTQELDNLAAEIAAGLTCNHPDYAILAARIAVSNLHKETKKAFSDVFEDLYNHVNKETNQKVPLVSEFHYNVVKKNATRLNSSIIYDRDFGYNYFGFKTLERSYLLKRNGKIAERPQHMLMRVAIGIHGEDIDAAVETYNLLSERYFTHASPTLFAAATNRPQLSSCFLLTMTADSIEGIFKSVEQCAMISKSAGGIGLNVHCIRAKGTSICGTNGTSNGLVPMLRVFNNVARYVDQGGGKRPGAFAIYLEPWHSDVFEFLELKKNTGKEENRARDLFYALWIPDLFMKRVEANGDWSLMCPHKCPGLHDVWGDEFEKLYEKYEQE-GRANRTVKAQSLWFAIIEAQVETGNPYMLFKDACNRKSNQQNVGTIKCSNLCTEIVEYSAPDEIAVCNLASIALNMFVTP--------EKTYDFKKLKEVTKIVTKNLNKIIDINYYPLPEARKSNLRHRPVGIGIQGFADALILMRFPYESEEAGLLNQQIFETIYYGALEASCELAQTEGPYETYEGSPVSKGILQYDMWDKVPTNLWDWQKLKESIRMHG-VRNSLLVAPMPTASTAQIMGNNESFEPYTTNIYTRRVLSGEFQVVNHHLLRDLTELDLWDDDMKNQIISSRGSIQNIETIPPKVRDLYKTVWEISVKSTIKMAADRGAFIDQSQSFNIHVAEPNYGKLTSIHFYSWKAGLKTGMYYLRTKPAANAIQFTVN-------------------------------------KKQGAVSMNGQNGTAEGSP----------------------------------QKYEEDRERKMADMVCSLE------------NKDACMSCGS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q54Q71-1", "uniprot_id": "RIR1_DICDI", "id": "Q54Q71-1", "name": "Ribonucleoside-diphosphate reductase large subunit", "aln": "MISNSINVTPNKESKMYVVKRDGTKENVSFDKITSRISFLCEMEPKLNSDIVDPIEVAQKVVSGVFPGVKTTELDNLAAETAAYMSTRHPDYGILAARISVSNLHKQTSKSFVETVKKQYEFINPKSNLLAPLVSKELYEIVMKHGERLESVIDYYRDFDYDFFGFKTLERSYLHRINGKIVERPQHMLMRVSIGIHGEDLESAINTYKRLSEKLFTHATPTLFNAGTPSPQMSSCFLVQMKEDSIDGIYDTLKQCALISKSAGGIGIAVHKIRAAQSYIRGTNGTSNGLVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADVFEFIDLKKNTGKEEMRARDLFYALWVSDIFMERVEQNGDWALFCPNEAPGLAETHSEEHRALYLKYEATPDLPRRVIKAQELWFAIMESQVETGTPFILYKDACNAKSNQKNLGTISSSNLCTEIIQYTSPDEIAVCNLASIALPKFVRQKVGSTDPKEKEFDHQFLFEITKLITVNLNVIIDRNYYPVAEAKTSNLRHRPIGIGIQGLADVFIKMRMPFDSVAAAKLNVEIAETIYFAALTASHELAIRDGTYESFKGSPASKGILQFDMWNVTPSSRWNWAELKDNIVNKGGLRNSLLIAPMPTASTSQILGNNECFEPYTSNIYSRRVLAGEFTIVNKQLLEDLMELGIWSPEMKNQIVAARGSIQSIGGIPDDLKELYKTVWEIRQRTLIDMAADRGAFIDQSQSFNVFIAEPTFAKLTSMHFYSWKKGLKTGMYYLRTRPAADAIQFTVDPIVSQTPKP----------------------------VENNINSTTPLKTPTKTPNSSNRISTSPTNNLT-------SPIRFNITQQQQQQQQQQQQQNNNEDDLANYDGM-------TCRREEGCLVCGS", "tax_id": 44689, "tax_name": "Social amoeba" }, { "uniprot_ac": "P21524-1", "uniprot_id": "RIR1_YEAST", "id": "P21524-1", "name": "Ribonucleoside-diphosphate reductase large chain 1", "aln": "---------------MYVYKRDGRKEPVQFDKITARISRLCYG---LDPKHIDAVKVTQRIISGVYEGVTTIELDNLAAETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVVEDLYRYVNAATGKPAPMISDDVYNIVMENKDKLNSAIVYDRDFQYSYFGFKTLERSYLLRINGQVAERPQHLIMRVALGIHGRDIEAALETYNLMSLKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECALISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALYLEPWHADIFDFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLSDCYGDEFEALYTRYEKE--GRGKTIKAQKLWYSILEAQTETGTPFVVYKDACNRKSNQKNLGVIKSSNLCCEIVEYSAPDETAVCNLASVALPAFIETS---EDGKTSTYNFKKLHEIAKVVTRNLNRVIDRNYYPVEEARKSNMRHRPIALGVQGLADTFMLLRLPFDSEEARLLNIQIFETIYHASMEASCELAQKDGPYETFQGSPASQGILQFDMWDQKPYGMWDWDTLRKDIMKHG-VRNSLTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGMKQYLITQNGSIQGLPNVPQELKDLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFLRAPTMGKLTSMHFYGWKKGLKTGMYYLRTQAASAAIQFTIDQKIADQATENVADISNLKRPSYMPSSASYAASDFVPAAVTANATIPSLDSSSEASREASPAPTGSHSLTKGMAELNVQESKVEVPEVPAPTKNEEKAAPIVDDEETEFDIYNSKVIACAIDNPEACEMCSG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* **** :* * *****:**. ** *: . :*. :: :::.*:: **.* ***.**** .* : ****. *****::*****:*.* * ...:. ...:* .. *:::. ::* : :*:* * * *** *.:*********** : .*::.*****::***::*** .*: :*::**: :* : ****:**** *.* **:*****: *. ***:**:.::::**:***:*****: : **: * ****.****:**:** *:.********.** ****:****** *:*:*::::** **** ****** ***:.*:**:*** * *:*:.* ..*** : .:*.. ** ** :.:***.**::*:*:*.***.*::::**:** ***::*:*.*..**** **::*:: ** *******:** :: ::. * .::*::. *** :** ****: ** ** ***:.:*:**:**.:: :* *::* * ** :* ****..:: :* :** *.*::: *.*.*:****:***: * . *:* *:..* * :**** :********:**:* **.:** *:*:* ****:*** :** **.** : .:* **: ::: .**** : :* .:::******** :: :.***:*..:****:*:*:.: *. .****:***.** ***********:..: .****:: . : : :: . : . . * *..", "identical_positions": 374, "similar_positions": 240, "identity": "41.01%" }, { "cls_id": "homologset.oma.809880", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P21672-1", "uniprot_id": "RIR3_YEAST", "id": "P21672-1", "name": "Ribonucleoside-diphosphate reductase large chain 2", "aln": "MYVIKRDGRKEPVQFDKITSRITRLSYGLDPNRIDAVKVTQRIISGVYSGVTTVELDNLAAETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVIEDLHDWINPATGKHAPMISDEIYNIVMENKDTLNSAIVYDRDFQYTYFGFKTLERSYLLRLNGEVAERPQHLVMRVALGIHGSDIESVLKTYNLMSLRYFTHASPTLFNAGTPHPQMSSCFLIAMKDDSIEGIYDTLKECAMISKTAGGVGLHINNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALFLEPWHADIFDFVDIRKTHGKEEIRARDLFPALWIPDLFMKRVQEDGPWTLFSPSAAPGLDDVWGDEFEELYTRYEREGRGK-TIKAQKLWYAILQAQTETGTPFMVYKDACNRKTNQQNLGTIKSSNLCCEIVEYSSPDETAVCNLASIALPAFVEVS--------------EDGKTASYNFERLHEIAKVITHNLNRVIDRNYYPVPEARNSNMKHRPIALGVQGLADTYMMLRLPFESEEAQTLNKQIFETIYHATLEASCELAQKEGKYSTFEGSPASKGILQFDMWNAKPFGMWDWETLRKDIVKHGLRNSLTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDDSMKQYLITQNGSIQGLPNVPQELKELYKTVWEISQKTIINMAADRAIYIDQSHSLNLFLQAPSMGKITSMHFYGWKKGLKTGMYYLRTQAASAAIQFTIDQEVADQAATHIASVSELDRPVYVPKGTKFSEQKAASALTESSDNEKDASPVPSEQSSVSSAMSNVKLEDSVAPAVPTETIKEDSDEKKCDIYNEKVIACTAPTPEACESCSG", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9SJ20-1", "uniprot_id": "RIR1_ARATH", "id": "Q9SJ20-1", "name": "Ribonucleoside-diphosphate reductase large subunit", "aln": "MYVVKRDGRQETVHFDKITARLKKLSYGLSSDHCDPVLVAQKVCAGVYKGVTTSQLDELAAETAAAMTCNHPDYASLAARIAVSNLHKNTKKSFSETIKDMFYHVNDRSGLKSPLIADDVFEIIMQNAARLDSEIIYDRDFEYDYFGFKTLERSYLLKVQGTVVERPQHMLMRVAVGIHKDDIDSVIQTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKDDSIEGIYETLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADVYEFLELRKNHGKEEHRARDLFYALWLPDLFMERVQNNGQWSLFCPNEAPGLADCWGAEFETLYTKYEREGKAKKVVQAQQLWYEILTSQVETGTPYMLFKDSCNRKSNQQNLGTIKSSNLCTEIIEYTSPTETAVCNLASIALPRFVREKGVPLDSHPPKLAGSLDSKNRYFDFEKLAEVTATVTVNLNKIIDVNYYPVETAKTSNMRHRPIGIGVQGLADAFILLGMPFDSPEAQQLNKDIFETIYYHALKASTELAARLGPYETYAGSPVSKGILQPDMWNVIPSDRWDWAVLRDMISKNGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHLLHDLTDMGLWTPTLKNKLINENGSIVNVAEIPDDLKAIYRTVWEIKQRTVVDMAADRGCYIDQSQSLNIHMDKPNFAKLTSLHFYTWKKGLKTGMYYLRSRAAADAIKFTVDTAMLKEKP----SVAEGDK------------------EVEEEDNE-------------------TKLAQ---------------------------MVCSLTNPEECLACGS", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*****:*.*:*****:*:.:*****..:: *.* *:*:: :***.**** :**:*****.* ** *****:******:*****:*.*.**:.*:*:. :* :* ::*:*:*::::*:*:* *:* *:*****:* *************:::* *.*****::****:*** .**:**::**:*** *:**************:**:*****:.**********:******:***:***:*: ::***:***** ********::**:****:*********.** ****::*******:::*:::**.***** ****** ***:*****:***::* *:**.*. **** * ** *** ***:*****:.* .::**:*** ** :*.*****:*::**:****:************** **:**:** ************* **. . *.*. ::**:* *:: .:* ***::** ***** *:.***:****.:*******::::* :**:* *** ***:******: :*:** *** : * *.*: ***.****** ****. * . *** .**. * *:*:**** :************* ****** ***:********** *** :**:**.*:*:* ::*: **.:**** .:.::*::** :*:*****.*:*:::*****. *****:***:.:: *.:.*:**:*** *************::**: **:**:* : .: . **:* *: .*..*** .** : :.*: ..** * :*..", "identical_positions": 508, "similar_positions": 207, "identity": "57.47%" }, { "cls_id": "homologset.oma.809937", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O75884-1", "uniprot_id": "RBBP9_HUMAN", "id": "O75884-1", "name": "Serine hydrolase RBBP9", "aln": "MASPSKAVIVPGNGGGDVTTHGWYGWVKKELEKIPGFQCLAKNMPDPITARESIWLPFMETELHCDEKTIIIGHSSGAIAAMRYAETHRVYAIVLVSAYTSDLGDENERASGYFTRPWQWEKIKANCPYIVQFGSTDDPFLPWKEQQEVADRLETKLHKFTDCGHFQNTEFHELITVVKSLLKVPA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1SBH3-1", "uniprot_id": "F1SBH3_PIG", "id": "F1SBH3-1", "name": "Serine hydrolase RBBP9", "aln": "MASPSKAVIVPGNGGGDVATHGWYGWVKKRLEQIPGFQCLAKNMPDPITARESIWLPFMETELRCDEETIIIGHSSGAIAAMRYAETHRVYAIVLVSAYTSDLGDENERASGYFSRPWQWEKIKANCPHIVQFGSTDDPFLPWKEQQEVADRLEAKLYSFTDRGHFQNTEFHELVNVVKSLLKVQA", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0AAA9SZ65-1", "uniprot_id": "A0AAA9SZ65_BOVIN", "id": "A0AAA9SZ65-1", "name": "Serine hydrolase RBBP9", "aln": "MAAPCKAVIIPGNGGEDVATHGWYGWVKRELEQIPGFQCLSKNMPDPITARESIWLPFMEMELHCDEETIIIGHSSGAIAAMRYAETHRVYAIVLVAAYTSDLGDANERASGYFSRPWQWEKIKANCPHIVQFGSTDDPFLPWKEQQEVADRLEAKLYKFTDRGHFQNTEFHELVSAVGSMLKVPA", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "O88851-1", "uniprot_id": "RBBP9_MOUSE", "id": "O88851-1", "name": "Serine hydrolase RBBP9", "aln": "MASPNKAVIVPGNGGGDVATHGWYGWVKKGLEQIPGFQCLAKNMPDPITARESIWLPFMETELHCDEKTIIIGHSSGAIAAMRYAETHQVYALVLVSAYTSDLGDENERASGYFSRPWQWEKIKANCPHIVQFGSTDDPFLPWKEQQEVADRLDAKLYKFTDRGHFQNTEFHELISVVKSMLKGPE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88350-1", "uniprot_id": "RBBP9_RAT", "id": "O88350-1", "name": "Serine hydrolase RBBP9", "aln": "MASPTKAVIVPGNGGGDVATHGWYGWVRKGLEQIPGFQCLAKNMPDPITARESIWLPFMETELHCDEKTIIIGHSSGAIAAMRYAETHQVYALILVSAYTSDLGDENERASGYFSRPWQWEKIKANCPHIIQFGSTDDPFLPWKEQQEVADRLDAKLYKFTDRGHFQNTEFHELIRVVKSMLTPAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3GVW2-1", "uniprot_id": "G3GVW2_CRIGR", "id": "G3GVW2-1", "name": "Serine hydrolase RBBP9", "aln": "MAFPVKAVIVPGNGGGDVATQGWYGWVRKRLEQIPGFQCLAKNMPDPITARESIWLPFMETELHCDEKTIIIGHSSGAIAAMRYAETHQVYGLVLVSAYTSDLGDENERASGYFSRPWQWEKIKANCPHIVQFGSTDDPFLPWKEQAEVADRLNAKLYKFDNRGHFQNTEFHELISVVKSMLKVPE", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * ****:***** **:*:******:: **:*******:******************* **:***:********************:**.::**:******** ********:*************:*:*************** ******::**:.* : ***********: .* *:*. ", "identical_positions": 146, "similar_positions": 26, "identity": "78.49%" }, { "cls_id": "homologset.oma.810439", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AN52-1", "uniprot_id": "A0A8I6AN52_RAT", "id": "A0A8I6AN52-1", "name": "", "aln": "MRVLCAFPEAMSSSSSRPPSCLALVALFLALLLPLSLSFHAGNRRPLPVDRATGLKEKTLILLDVSTKNPVRTVSENFLSLHLDPSIIHDGWLDFLSSKRLVTLARGLSPAFLRFGGKRTDFLQFQNLRNPAKSRGGPGPDYYLKNYEDDIVRSDVALDKQKGCKIAQHPDIMLELQREKAAQMHLVLLKEQYSNTYSNLILTARSLDKLYNFADCSGLHLIFALNALR-------RNPNNSWNSSSALSLLKYSASKKYNIS-WELGNEPNNYRSIHGRAVNGSQLGKDYIQLRSLLQPIRIYSRAGLYGPSIGRPR-KNVIALLDGFLKVAGSTVDAVTWQHCYIDG---RVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKIWLEGIVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFNPLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSIT--LFIINLHRSRKKIKLAGTLR-------DKLVHQYLLQP-----YGQEGLKSKSVQLNGQPLVMVDDGTLPELKPRPLRAGRTLVIPPVTMGFYVVKNVNALACRYR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RY83-1", "uniprot_id": "HPSE2_MOUSE", "id": "B2RY83-1", "name": "Inactive heparanase-2", "aln": "MRVLCAFPEAMASSSSRPPSCLALVALFLALLLHLSLSFHAGNRRPLPVDRATGLKEKTLILLDVSTKNPVRTVNENFLSLQLDPSIIHDGWLDFLSSKRLVTLARGLSPAFLRFGGKRTDFLQFQNLRNPAKSRGGPGPDYYLKNYEDDIVRSDVALDKQKGCKIAQHPDVMLELQREKASQMHLVLLKEQYSNTYSNLILTARSLDKLYNFADCSGLHLIFALNALR-------RNPNNSWNSSSALSLLKYSASKKYNIS-WELGNEPNNYRSIHGRAVNGSQLGKDYIQLKSLLQPIRVYSRASLYGPNIGRPR-KNVIALLDGFMKVAGSTVDAVTWQHCYIDG---RVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKIWLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFNPLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSIT--LFIINLHRSRKKIKLAGTLR-------DKLVHQYLLQP-----YGQEGLKSKSVQLNGQPLVMVDDGTLPELKPRPLRAGRTLVIPPVTMGFYVVKNVNALACRYR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWQ2-1", "uniprot_id": "HPSE2_HUMAN", "id": "Q8WWQ2-1", "name": "Inactive heparanase-2", "aln": "MRVLCAFPEAMPSSNSRPPACLAPGALYLALLLHLSLSSQAGDRRPLPVDRAAGLKEKTLILLDVSTKNPVRTVNENFLSLQLDPSIIHDGWLDFLSSKRLVTLARGLSPAFLRFGGKRTDFLQFQNLRNPAKSRGGPGPDYYLKNYEDDIVRSDVALDKQKGCKIAQHPDVMLELQREKAAQMHLVLLKEQFSNTYSNLILTARSLDKLYNFADCSGLHLIFALNALR-------RNPNNSWNSSSALSLLKYSASKKYNIS-WELGNEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRPR-KNVIALLDGFMKVAGSTVDAVTWQHCYIDG---RVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKIWLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFNPLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSIT--LFIINLHRSRKKIKLAGTLR-------DKLVHQYLLQP-----YGQEGLKSKSVQLNGQPLVMVDDGTLPELKPRPLRAGRTLVIPPVTMGFYVVKNVNALACRYR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1S8W7-1", "uniprot_id": "F1S8W7_PIG", "id": "F1S8W7-1", "name": "", "aln": "MRVLCAFPEAMPSSNSRPPACLAPVALFLALLLHLSLSSQAGDRRPLPVDRAPGLKEKTLILLDVSTKNPVRTVNENFLSLQLDPSIIHDGWLDFLSSKRLVTLARGLSPAFLRFGGKRTDFLQFQNLRNPAKSRGGPGPDYYLKNYEDDIVRSDVALDKQKGCKIAQHPDVMLELQREKAAQMHLVLLKEQFSNTYSNLILTARSLDKLYNFADCSGLHLIFALNALR-------RNPNNSWNSSSALSLLKYSASKKYNIS-WELGNEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRPR-KNVIALLDGFMKVAGSTVDAVTWQHCYIDG---RVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKIWLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFNPLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSIT--LFIINLHRSRKKIKLAGTLR-------DKLVHQYLLQP-----YGQEGLKSKSVQLNGQPLTMVDDGTLPDLKPRPLRAGRTLVIPPVTMGFYVVKNVNALACRYR", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "F1NM73-1", "uniprot_id": "F1NM73_CHICK", "id": "F1NM73-1", "name": "", "aln": "----------MPCSISCPPGLLALMAPGLALMATFSLPSQAGDRRALPVEKSPGVKGRTLILLDVNTKSPVRIISENFLSLQLDPSIIHDGWLDFLSSRRLVTLARGLAPAFLRFAGKRTDFLQFHNVKNPAKSRGGPGPDYYLKNYEDDIVRSDIALDKQKGCKIAQHPDIMLELQREKAAQMHLVLLKEQFSNTYSNLTLTARSLDKLYNFADCSGLHLIFALNALR-------RNPNNSWNSSNALSLLKYSASKKYNIS-WELGNEPNNYRTLIGRSVNGSQLGKDYIQLRSLLQLIRTYSRANLYGPNIGRPR-KNVMALLEGFMKVAGSTVDAVTWQHYYIDG---RVAKVTDFLKTRLLDTLSDQIRKIQKVVNAYTPGKKIWLEGVGATSAGGMNNLSDSYAAGFLWLNTLGLLASQGIDVVVRHSFLDHGHNHLVDQNFNPLPDYWLSLLYKRLIGPKVLAIHVAGLQRKPRPGRVIRDKLRIYAHCTSSHNHNYVRGSIT--LYIINLHRSRKKIKLAGTLR-------DKIVHQYLLQP-----YGKDGLHSKSVQLNGQPLAMVDDGTLPELKPRPLRAGRTLVIPPLTMSFYVVKNVNALACRYR", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9FF10-1", "uniprot_id": "HPSE1_ARATH", "id": "Q9FF10-1", "name": "Heparanase-like protein 1", "aln": "---------------MGFRVCVIVVFLGCLLLVPEKTMAQEMKRASIVIQGAR----------------RVCETDENFVCATLDWWPHDKCNYDQCPWGYSSVINMDLTRPLLTKAIK-----AFKPLR----------------------IRIGGSLQDQVIYDVGNLKTPCRPFQKMNSGLFG-----------FSKGCLHMKRWDELNSFLTATGAVVTFGLNALRGRHKLRGKAWGGAWDHINTQDFLNYTVSKGYVIDSWEFGNELS--GSGVGASVSAELYGKDLIVLKDVIN--KVYKNSWLHKPILVAPGGFYEQQWYTKLLEISGPSVVDVVTHHIYNLGSGNDPALVKKIMDPSYLSQVSKTFKDVNQTIQEHGPWASPWVGESGGAYNSGGRHVSDTFIDSFWYLDQLGMSARHNTKVYCRQTLVGGFYGLLEKGTFVPNPDYYSALLWHRLMGKGVLAVQTDGPPQLRVYAHCSKGRAGVTLLLINLSNQSDFTVSVSNGINVVLNAESRKKKSLLDTLKRPFSWIGSKASDGYLNREEYHLTPENGVLRSKTMVLNGKSLKPTATGDIPSLEPVLRSVNSPLNVLPLSMSFIVLPNFDASACS--", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: . : .* .: :: : * .***:. ** .. * . .: .*: .:* . * *: :: :* . :*:.* .:.: :*: ::. : :*: * : *:* .* .:* : *.***** : ..:*: .: .:*:*:.** * *. **:*** . : * :*... *** * *:.::: : *..: *: * : * :::::*.:* *. :* * * . * .::.. *. :*. ::.:::.:: : * . *: : .* .::**:: .* :*: **: * :. .* *:::.. :. * . .* * ***: :**::**:* ***::. * : .: :.: : . *:. . *:: : :: .**** .* .**: .* . ** : : *:**:: ***:.* . * :*.*:* .. .* : *::*.* *: *.:* ** ", "identical_positions": 120, "similar_positions": 185, "identity": "19.42%" }, { "cls_id": "homologset.oma.810440", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y251-1", "uniprot_id": "HPSE_HUMAN", "id": "Q9Y251-1", "name": "Heparanase", "aln": "--------MLLRSKPALPPPLMLLL--LGPLGPLSPGALPRPAQAQDVVDLDFFTQEPLHLVSPSFLSVTIDANLATDPRFLILLGSPKLRTLARGLSPAYLRFGGTKTDFLIFDPKKESTFEERSYWQSQVNQDICKYGSIPPDVEEKLRLEWPYQEQLLLREHYQKKFKNSTYSRSSVDVLYTFANCSGLDLIFGLNALLRTADLQWNSSNAQLLLDYCSSKGYNIS-WELGNEPNSFLKKADIFINGSQLGEDFIQLHKLLRKSTFKNAK-LYGPDVGQPRRKTAKMLKSFLKAGGEVIDSVTWHHYYLNG--RTATKEDFLNPDVLDIFISSVQKVFQVVESTRPGKKVWLGETSSAYGGGAPLLSDTFAAGFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLLFKKLVGTKVLMASVQGSK--RRKLRVYLHCTNTDN------PRYKEGDLTLYAINLHNVTKYLRLPYPFSNKQVDKYLLRP-------------LGPHGLLSKSVQLNGLTLKMVDDQTLPPLMEKPLRPGSSLGLPAFSYSFFVIRNAKVAACI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1N1G1-1", "uniprot_id": "F1N1G1_BOVIN", "id": "F1N1G1-1", "name": "Heparanase", "aln": "MLACRKPGMLACRKPGLRPPLLLLLPLLGPLGPCSPGTPAAAAPADDAAELEFFTERPLHLVSPAFLSFTIDANLATDPRFFTFLGSSKLRTLARGLAPAYLRFGGNKGDFLIFDPKKEPAFEERSYWLSQSNQDICKSGSIPSDVEEKLRLEWPFQEQVLLREQYQKKFTNSTYSKHSVDMLYTFASCSGLNLIFGLNALLRTTDMHWDSSNAQLLLDYCSSKNYNIS-WELGNEPNSFQRKAGIFINGRQLGEDFIEFRKLLGKSAFKNAK-LYGPDIGQPRRNTVKMLKSFLKAGGEVIDSVTWHHYYVNG--RIATKEDFLNPDILDTFISSVQKTLRIVEKIRPLKKVWLGETSSAFGGGAPFLSNTFAAGFMWLDKLGLSARMGIEVVMRQVLFGAGNYHLVDGNFEPLPDYWLSLLFKKLVGNKVLMASVKGPD--RSKLRVYLHCTNTKH------PRYKEGDLTLYALNLHNVTKHLELPHHLFNKQVDKYLIKP-------------SGPDGLLSKSVQLNDQILKMVDEQTLPALTEKPLHPGSSLGMPPFSYGFFVIRNAKVAACI", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q71RP1-1", "uniprot_id": "HPSE_RAT", "id": "Q71RP1-1", "name": "Heparanase", "aln": "--------MLRP---------LLLLWLWGRLGALTQGTPAGTAPTKDVVDLEFYTKRLFQSVSPSFLSITIDASLATDPRFLTFLGSPRLRALARGLSPAYLRFGGTKTDFLIFDPNKEPTSEERSYWQSQDNNDICGSERVSADVLRKLQMEWPFQELLLLREQYQREFKNSTYSRSSVDMLYSFAKCSRLDLIFGLNALLRTPDLRWNSSNAQLLLNYCSSKGYNIS-WELGNEPNSFWKKAHISIDGLQLGEDFVELHKLLQKSAFQNAK-LYGPDIGQPRGKTVKLLRSFLKAGGEVIDSLTWHHYYLNG--RVATKEDFLSSDVLDTFILSVQKILKVTKEMTPGKKVWLGETSSAYGGGAPLLSDTFAAGFMWLDKLGLSAQLGIEVVMRQVFFGAGNYHLVDENFEPLPDYWLSLLFKKLVGPKVLMSRVKGPD--RSKLRVYLHCTNVYH------PRYREGDLTLYVLNLHNVTKHLKLPPPMFSRPVDKYLLKP-------------FGSDGLLSKSVQLNGQTLKMVDEQTLPALTEKPLPAGSSLSVPAFSYGFFVIRNAKIAACI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6YGZ1-1", "uniprot_id": "HPSE_MOUSE", "id": "Q6YGZ1-1", "name": "Heparanase", "aln": "--------MLR----------LLLLWLWGPLGALAQGAPAGTAPTDDVVDLEFYTKRPLRSVSPSFLSITIDASLATDPRFLTFLGSPRLRALARGLSPAYLRFGGTKTDFLIFDPDKEPTSEERSYWKSQVNHDICRSEPVSAAVLRKLQVEWPFQELLLLREQYQKEFKNSTYSRSSVDMLYSFAKCSGLDLIFGLNALLRTPDLRWNSSNAQLLLDYCSSKGYNIS-WELGNEPNSFWKKAHILIDGLQLGEDFVELHKLLQRSAFQNAK-LYGPDIGQPRGKTVKLLRSFLKAGGEVIDSLTWHHYYLNG--RIATKEDFLSSDVLDTFILSVQKILKVTKEITPGKKVWLGETSSAYGGGAPLLSNTFAAGFMWLDKLGLSAQMGIEVVMRQVFFGAGNYHLVDENFEPLPDYWLSLLFKKLVGPRVLLSRVKGPD--RSKLRVYLHCTNVYH------PRYQEGDLTLYVLNLHNVTKHLKVPPPLFRKPVDTYLLKP-------------SGPDGLLSKSVQLNGQILKMVDEQTLPALTEKPLPAGSALSLPAFSYGFFVIRNAKIAACI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A061INU8-1", "uniprot_id": "A0A061INU8_CRIGR", "id": "A0A061INU8-1", "name": "Heparanase", "aln": "------MRLLLL---------LCLWWLWGPLSALAQGAPAGTARAEDVVDLEFSTERPLHLVSPSFLSVTIDANLATDPRFLTFLGSPRLRTLARGLSPAYLRFGGTKTDFLIFDPKKEPTFEERSYWQSQVNHDVCRSEPVSPDVMRRLQEEWPFLELLLLKEQYQREFKNSTYSRSSVDMLYSFAKCSGLDLIFGLNALLRTPDLRWNSSNAQLLLEYCASKGYNIS-WELGNEPNSFWKKAHIFIDGLQLGEDFVQFRKLLRKSAFKNAK-LYGPDVGQPRGKTVKLLRSFLKAGGEVIDALTWHHYYLNG--RIATKEDFLSSDVLDTFISSVQKVLKVTKEMRPGKKVWLGETSSAYGGGAPSLSNTFAAGFMWLDKLGISAQMGIEVVMRQVFFGAGNYHLVDENFEPLPDYWLSLLFKKLVGPQVLMVRVKGLD--RSKLRMYLHCTNTHH------PKYQDGDLTLYVLNLHNVTKHVNLPYQLFNKPVDKYLLKP-------------FGPEGLLSKSVQLNGETLKIVDDHTLPALTEKPLRPGSSLGMPAFSYGFFVIRNAKIAACL", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q1LVP9-1", "uniprot_id": "Q1LVP9_DANRE", "id": "Q1LVP9-1", "name": "Heparanase", "aln": "--MKSAATALST---------IFALLLFDPV-YLEAKTVISVDDVGQFVRVDVDLSRVARRVDERFLSVAIDASLLTEEKFMNLLNSPKLRTLAKALTPAFLRFGGTKQDFLKFSPRGRYYLQGRENGSSAFQGNVCMRLELPPLLENRLKQEWVQQSKSLLLKELDGKYRNTKFSEDSVDLLYSFANCSGLELIFGLNALLRTSRNCWDSGNAKLLLKYCESRQYMMS-WELGNEPNSYEKKAGVRVDGFQLGRDFMHLHQILQESTIYNSTGLYGPDVSQPKDHRKDLLTGFLETGGKVINACTWHHYYVNG--RDTSLEDFLDPEVLDSLATKINEVLEMVEAVSPGKKVWLGETSSAYGGGAVGLSDTFVAGFMWLDKLGLAAKLGLNLVIRQVLIGAGTYHLVDDNLDPLPDYWLSLLFKRLVGQEVLKADVTVNSGLKKPIRVYLHCTNKKS------TQYKEGAVTLFALNLNKNEATINLPAHLTNGSIEAFVLQSDE-----------AGEQGLYSRSVRLNGELLKMVDDRTLPPLTGRELPSDEPIKLPAFSFAFYVLINAQAAVCK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9FZP1-1", "uniprot_id": "HPSE3_ARATH", "id": "Q9FZP1-1", "name": "Heparanase-like protein 3", "aln": "--MAYR----------------QILAIVLFLCVFQFLDCTVSSAVEENGTVFVYGRAAVGTIDEDFICATLDWWPPEKCDYG---SCSWDHASILNLDLNNVILQNAIKAFAPLKIRIGGTLQDIVIYETPDSKQPCLP------FTKNSSILFGYTQGCLPMRRWD--ELNAFFRKTGTKVIFGLNALSGRSIKSNGEAIG-----AWNYTNAESFIRFTAENNYTIDGWELGNELCGSGVGARVGAN--QYAIDTINLRNIVNR-VYKNVS-PMPLVIGPGGFFEVDWFTEYLNKAENSLNATTRHIYDLGPGVDEHLIEKILNPSYLDQEAKSFRSLKNIIKNSSTKAVAWVGESGGAYNSGRNLVSNAFVYSFWYLDQLGMASLYDTKTYCRQSLIGGNYGLLNTTNFTPNPDYYSALIWRQLMGRKALFTTFSGTK----KIRSYTHCARQSKGITVLLMNLDNTTTVVAKVELNNSFSLRHTKHMKSYKRASSQLFGGPNGVIQREEYHLTAKDGNLHSQTMLLNGNALQVNSMGDLPPIEPIHINSTEPITIAPYSIVFVHMRNVVVPACA", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : . :. *:. ::* . : ... :: * : : . * :. : : . : * . .. : . * .. : *: : . ...::: : * .: . :*: *: **: :: : .. * :. ****** . * : : * . * :.::::: . . * . :. . : :*: . : ::: * * * :. *.:*... ** .... .: : . .*:**:..*:..* :*::*. .* :**:**::: . : ** ::*.. * *: * ***: :*::::*:* ..* . . :* * **:. . : .: ::*:: . . :: .* *::: **. *:: . **.: : . ..: :..:* * : *. ..* ", "identical_positions": 72, "similar_positions": 173, "identity": "12.46%" }, { "cls_id": "homologset.oma.810784", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A7YWI9-1", "uniprot_id": "TYDP2_BOVIN", "id": "A7YWI9-1", "name": "Tyrosyl-DNA phosphodiesterase 2", "aln": "MERNSGPEAGP-----------EAELEEGEPEVKKRKLMCVEFASVASCDAAVAQCYLAENDWEMERALNSYFEPAVEESASESRPESLSEPGSCVDLTKEETNDSISSKTSTSEDKSVQQEDGSVFSFITWNIDGLDMNNLLERARGVCSYLTLYSPDVIFLQEVIPPYYAYLKKKASSYKIITGREEGYFTAIMLKKSRVKFKSQEIIPFPNTQMMRNLLCVHVSVSGNELCLMTSHLESTRGHAKERMNQFKMVLEKMQEAPGSATVIFAGDTNLRDQEVTKCGGLPNNILDVWEFLGKPKHCQYTWDTQMNSNLGIAANCKLRFDRIFFRAAAEGGHIIPQSLDLLGLEKLDCGRFPSDHWGLLCTLDVIL", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A5G2R2R0-1", "uniprot_id": "A0A5G2R2R0_PIG", "id": "A0A5G2R2R0-1", "name": "Tyrosyl-DNA phosphodiesterase 2", "aln": "MEQKSGLEDGP-----------ELEQEEGEPEVKKRRLLCVEFASVATCDAAVAQCYLAENDWEMERALNSYFEPAVEENALKSRPETPNEPESCVDLTKEETSDSFSCKTSTSEN--VQQEDGSVFSFITWNIDGLDLNSLLERARGVCSYLALYSPDVIFLQEVIPPYYTYLKKKASSYEIITGNEEGYFTAIMLKKSRVKFKSQEIIPFPNTKMMRNLLCVHVSVSGNELCLMTSHLESTRGHAEERMNQLKMVLKKMQEAPESATVIFAGDTNLRDQEVTKCGGLPNNILDVWEFLGKPKHCQYTWDTQMNSNLGIAATCKLRFDRIFFRAAAEGSHIIPRSLDLLGLEKLDCGRFPSDHWGLLCNLDVIL", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "O95551-1", "uniprot_id": "TYDP2_HUMAN", "id": "O95551-1", "name": "Tyrosyl-DNA phosphodiesterase 2", "aln": "MELGSCLEGGR-----------EAAEEEGEPEVKKRRLLCVEFASVASCDAAVAQCFLAENDWEMERALNSYFEPPVEESALERRPETISEPKTYVDLTNEETTDSTTSKISPSED--TQQENGSMFSLITWNIDGLDLNNLSERARGVCSYLALYSPDVIFLQEVIPPYYSYLKKRSSNYEIITGHEEGYFTAIMLKKSRVKLKSQEIIPFPSTKMMRNLLCVHVNVSGNELCLMTSHLESTRGHAAERMNQLKMVLKKMQEAPESATVIFAGDTNLRDREVTRCGGLPNNIVDVWEFLGKPKHCQYTWDTQMNSNLGITAACKLRFDRIFFRAAAEEGHIIPRSLDLLGLEKLDCGRFPSDHWGLLCNLDIIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3T1H5-1", "uniprot_id": "TYDP2_RAT", "id": "Q3T1H5-1", "name": "Tyrosyl-DNA phosphodiesterase 2", "aln": "MASGSSSDAAESAEPA----AAPAAAETEEDQVKRRRLQSLGFALVTSCDTTVASTFLSENNWQTKKALSAFFEQPENDLARPHQPPTSSKSEDYVDLTNEDANDTTILETSPSGT---PLEDSSTISFITWNIDGLDGCNLPERARGVCSCLALYSPDVVFLQEVIPSYCAYLRKRARTYNIITGNEEGYFTAILLKKGRVKFKGQEIIPFPNTKMMRNLLCVNVSLGGNEFCLMTSHLESTRKHSAERINQLKTVFQKMQEATDSTTVIFAGDTNLRDQEVIKCGGLPDNVFDAWEFLGKPKHCRYTWDTKANDNLRIPAACKHRFDRIFFR--AEEGHLIPQSLDLIGLERLDCGRFPSDHWGLLCTLNVVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJX7-1", "uniprot_id": "TYDP2_MOUSE", "id": "Q9JJX7-1", "name": "Tyrosyl-DNA phosphodiesterase 2", "aln": "MASGSSSDAAEPAGPAGRAASAPEAAQAEEDRVKRRRLQCLGFALVGGCDPTMVPSVLRENDWQTQKALSAYFELPENDQGWPRQPPTSFKSEAYVDLTNEDANDTTILEASPSGT---PLEDSSTISFITWNIDGLDGCNLPERARGVCSCLALYSPDVVFLQEVIPPYCAYLKKRAASYTIITGNEEGYFTAILLKKGRVKFKSQEIIPFPNTKMMRNLLCVNVSLGGNEFCLMTSHLESTREHSAERIRQLKTVLGKMQEAPDSTTVIFAGDTNLRDQEVIKCGGLPDNVFDAWEFLGKPKHCQYTWDTKANNNLRIPAAYKHRFDRIFFR--AEEGHLIPQSLDLVGLEKLDCGRFPSDHWGLLCTLNVVL", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * : . : * .**:*:* .: ** * **.::. * **:*: ::**.::** . :: . :* : :. ****:*::.*: : *.* *:.* :*:********* .* ******** *:******:*******.* :**:*:: .* ****.********:***.***:*.*******.*:********:*.:.***:*********** *: **:.*:* *: *****. *:************:** :*****:*:.*.**********:*****: *.** *.* * ******** ** .*:**:****:***:***************.*:::*", "identical_positions": 210, "similar_positions": 85, "identity": "56.0%" }, { "cls_id": "homologset.oma.811067", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0AAA9RYE9-1", "uniprot_id": "A0AAA9RYE9_BOVIN", "id": "A0AAA9RYE9-1", "name": "Calcium-independent phospholipase A2-gamma", "aln": "MLLRIPSTIMPGCGIIYWNLSNARSLCGKQRSKQLPFLCSPEHYWRISH-ISLQRGVHMSRIRCKWTKSEAHSCSKHCSPLSHHGLHLAVLRLSTSAPKGLTKVSPRMSRIKNTLNSVSKAVFGKQNEMISRLAQLKPSSRILRKVTDSGWLKQKNVKQTIKFLKKYSDKSAEKSSIPAKESQVIEKD-DIGKPSLFHYTSNITTKFGESFYFLSSHINSYFKREEKMSQQNEDQHFQEKSELELKKVEDEKPSSPDPGILSDKKLDSEASLYSEDKPGSPSGTPEVLPISTKQSIANFLSRPTEGVQALVGGYIGGLVPKLKYDSKSQLEDQEEATKAEQAVSKDKNAEEKRRLSLQREKIIARVSIDNRTRALVQALRRTTDPRLCINRVEELTFHLLEFPEGKGVAVKEKIIPYLLRLRQIKDETLQAAVREILALIGYVDPVKGRGIRILSIDGGGTRGVVALQTLRKLVELTQKPVHQLFDYICGVSTGAILAFMLGLFHMPLDECEELYRKLGSDVFSQNVIVGTVKMSWSHAFYDSQTWENILKDRMGSSLMIETARNPKCPKVAAVSTIVNRGITPKAFVFRNYGHFPGINSHYLGGCQYKMWQAIRASSAAPGYFAEYALGNDLHQDGGLLLNNPSALAMHECKCLWPDVPLECIVSLGTGRYESDVRNNVTYTSLKTKLSNVINSATDTEEVHVMLDGLLPPDTYFRFNPVMCENIPLDESRNEKLNQLQLEGLKYIERNEEKMKKLAKILSQEKTTLQKINDWIKLKTDMYEGLPFFSKL", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1SAE7-1", "uniprot_id": "F1SAE7_PIG", "id": "F1SAE7-1", "name": "Calcium-independent phospholipase A2-gamma", "aln": "MSIHLTIDLY----YIYL-LSNARSLCGKQRSKELHFLCSPKHYWRISH-ISLQRGFHTSKIRWKWTKSEAHSRSKHYYSPSNHGVHIGILHLSTSAPKGLTKVSLRMSRIKSTLNSVSKAVWGKQNEMISRLAQLKPSSRILRKVSDGGWLKQRNVKQTIKFLKKYSDTSAEKSSFPAKDNHMLEKE-DTGKKSLFHYASSLTTKFEESFYFLSNHINSYFKCEEKMPQKQESKHSQDKSELELKKVEEEKPSSLDANVLTDKQQGSEA-VCALDKPASPSETPEVLRVSTKQCIANFFSRPTEGVQALVGGYIGGLVPKLKYEAKSQSEEQEEVLKAEQAVSGDRSTEEKRRLSLQREKIIARVSIDNRTRALVQALRRTADPRLCITRVEELTFHLLEFPEGKGVAVREKIIPYLLRLRQIKDETLQAAVREILALIGYVDPVKGRGIRILSIDGGGIRGVVALQTLRKLVELTQKPVHQLFDYICGVSTGAILAFMLGLFHMPLDECEELYRKLGSDVFSQNVIVGTVKMSWSHAFYDSQTWENILKDRMGSSLMIETARNPTCPKVAAVSTIVNRGITPKAFVFRNYGHFPGVNSHYLGGCHYKMWQAIRASSAAPGYFAEYALGNDLHQDGGLLLNNPSALAMHECKCLWPDVPLECIVSLGTGRYESDVRNTTTYTSLKTKLSNVINSATDTEEVHVMLDGLLPPDTYFRFNPVMCENIPLDESRNEKLNQLQLEGLKYIERNEEKMKKLAKILSQEKTTLQKINDWIKLKTDMYEGLPFFSKL", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q9NP80-1", "uniprot_id": "PLPL8_HUMAN", "id": "Q9NP80-1", "name": "Calcium-independent phospholipase A2-gamma", "aln": "MSINLTVDIY-----IYL-LSNARSVCGKQRSKQLYFLFSPKHYWRISH-ISLQRGFHTNIIRCKWTKSEAHSCSKHCYSPSNHGLHIGILKLSTSAPKGLTKVNICMSRIKSTLNSVSKAVFGNQNEMISRLAQFKPSSQILRKVSDSGWLKQKNIKQAIKSLKKYSDKSAEKSPFPEEKSHIIDKEEDIGKRSLFHYTSSITTKFGDSFYFLSNHINSYFKRKEKMSQQKENEHFRDKSELEDKKVEEGKLRSPDPGILAYKP-GSES-VHTVDKPTSPSAIPDVLQVSTKQSIANFLSRPTEGVQALVGGYIGGLVPKLKYDSKSQSEEQEEPAKTDQAVSKDRNAEEKKRLSLQREKIIARVSIDNRTRALVQALRRTTDPKLCITRVEELTFHLLEFPEGKGVAVKERIIPYLLRLRQIKDETLQAAVREILALIGYVDPVKGRGIRILSIDGGGTRGVVALQTLRKLVELTQKPVHQLFDYICGVSTGAILAFMLGLFHMPLDECEELYRKLGSDVFSQNVIVGTVKMSWSHAFYDSQTWENILKDRMGSALMIETARNPTCPKVAAVSTIVNRGITPKAFVFRNYGHFPGINSHYLGGCQYKMWQAIRASSAAPGYFAEYALGNDLHQDGGLLLNNPSALAMHECKCLWPDVPLECIVSLGTGRYESDVRNTVTYTSLKTKLSNVINSATDTEEVHIMLDGLLPPDTYFRFNPVMCENIPLDESRNEKLDQLQLEGLKYIERNEQKMKKVAKILSQEKTTLQKINDWIKLKTDMYEGLPFFSKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZRC4-1", "uniprot_id": "PLPL8_RAT", "id": "D3ZRC4-1", "name": "Calcium-independent phospholipase A2-gamma", "aln": "MSINLTLDIY-----IYF-LNNARSFCGKQRSKQLNFLCS-KQYWRMNH-VNVHREFHTSKKSCKWNRSEAH-CSKHWHSSSNHGVHIGIVKLSTSAPKGLTKVSIHMSRIKSTLNSVSKAIFGSQNEMVSRLAQFKPSSRIFRKVSDRGWLKHKNVKQAIESLKNYSDKSAEKNSFAEQKSYFADKEEGSDKHSLYHYAYRITTRFGESFYFLANHINSYFKNKEKMSQIKEDRQLQDKPCLE-----ESKSISPSPDILTDRP-DSGPPLNVEDKLSSSTQLPEALPVSTKQSIANFLSRPTEGVQALVGGYIGGLVPKLKSDPKSQPEEEEEPSKTDEPICKDKKAEEKKRVLLQREKIIARVSIDNRTRALVQALRRTTDPKLCITRVEELTFHLLEFPEGKGVAVKEKIIPYLLRLRQIKDETLQAAVREILALIGYVDPVKGRGIRILAIDGGGTRGVVALQTLRKLVELTQKPIHQLFDYICGVSTGAILAFMLGLFHMPLDECEELYRKLGSDVFTQNVIVGTVKMSWSHAFYDSHTWEKILKDKVGSALMIETARDPLCPKVAAVSTIVNRGQTPKAFVFRNYGHFPGTNSHYLGGCQYKMWQAIRASSAAPGYFAEYALGNDLHQDGGLLLNNPSALALHECKCIWPDTPLECIVSLGTGRYESDVRNTTTYTSLKTKLSNVISSATDTEEVHIMLDGLLPADTYFRFNPVICENIPLDESRNEKLDQLQLEGMKYLERNDEKMKKLAKILSREKTTLQKISDWIKLKSDMYEGLPFFSKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K1N1-1", "uniprot_id": "PLPL8_MOUSE", "id": "Q8K1N1-1", "name": "Calcium-independent phospholipase A2-gamma", "aln": "MSINLTLDIY-----IYF-LNNARSLCGKQRSKQLHFVCS-KQYWRMNH-VNVHREFHTSKKSCKWNRSEAH-CSKHWHSPSNHGLHFGIVRLSTSAPKGLTKVSIHMSRIKSTLNSVSKAIFGSQNEMVTRLAQFKPSSRILRKVSDKGWLKQKNVKQAVESLKNYSDKSAGKNSLAEQKSYFADKEEDSGKHSLFHYTYGITTRFGESFSVLANHINSYFKSKGKMSQTKEDKQLQDKPDLE-----ERKSSSPGPDTVADRP-DSESPLEVKDKLSSPTQMPEAHPVSAKQSIANFLSRPTEGVQALVGGYIGGLVPKLKSDPKSPPEEQEVSAKTEQAVNKDKKAEEKKRVLLQQEKIIARVSIDNRTRALVQALRRTADPKLCITRVEELTFHLLEFPEGKGVAIKEKIIPYLLRLRQVKDETLQAAVREILALIGYVDPVKGRGIRILTIDGGGTRGVVALQTLRKLVELTQKPIHQLFDYICGVSTGAILAFMLGLFHMPLDECEELYRKLGSDVFTQNVIVGTVKMSWSHAFYDSNTWEKILKDRIGSALMIETARNPACPKVAAISTIVNRGQTPKAFVFRNYGHFPGTNSHYLGGCQYKMWQAIRASSAAPGYFAEYALGSDLHQDGGLLLNNPSALALHECKCIWPDTPLECIVSLGTGRYESDVRNTSTYTSLKTKLSNVISSATDTEEVHIMLDGLLPSDTYFRFNPVICENIPLDESRDEKLDQLQLEGMKYIERNDQKMKKVAKILSQEKTTLQKINDWIKLKSDMYEGLPFFSKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3H0N8-1", "uniprot_id": "G3H0N8_CRIGR", "id": "G3H0N8-1", "name": "Calcium-independent phospholipase A2-gamma", "aln": "MSINLTLDIY-----IYF-LGNARSLCGNQRSKQLPFVCS-KNYWRVNQSLSVHRDFHTSKKSCKWSKGKAC-CSKHWHSPSDHGLHIGGLKLSTSAPKGLTKVSIHMSRIKSTLNSVSKAIFGSQNEMVSRLVQFKPSSRFLRKISDRGWLKQNNVKQAIESLKKYSDKSAEKNSIVEQKSYIADKEEDTGKRSLFHCTYNITNRVEESFYILTNHINIYFNRKEKMPQTKEIKHLQDKPDFE-----EGKSDSLSPNILTNTS-DSGSPLDAGDKPSSPSQMPEVLPGSAKQSIANFLSRPTEGVQALVGGYIGGLVPRLKSDSRSQPEGQEEPAKTEQAVSKDKKAEEKKRVSLQREKIIARVSIDNRTRALVQALRRTTDPKLCITRVEELTFHLLEFPEGKGVAVKEKIIPYLLRLRQIKDETLQAAVREILALIGYVDPVKGRGIRILTIDGGGTRGVVALQTLRKLVELTQKPIHQLFDYICGVSTGAILAFMLGLFHLPLDQCEELYRKLGSDVFSQNVIVGTVKMSWSHAFYDSHTWEKILQDRMGSALMIETARDPACPKVAAVSTIVNRGLTPKAFVFRNYSHFPGINSHYLGGCQYKLWQAIRASSAAPGYFAEYALGNDLHQDGGLLLNNPSALAMHECKCIWPDAPLECIVSLGTGRYESDVRNTTTYTSLKTKLSNVISSATDTEEVHVILDGLLPPDTYFRFNPVMCENIPLDESRNEKLDQLQLEGMKYIERNEQKMKKVAKILSQEKTTLQKINDWIKLKSDMYEGLPFFSKL", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :.:. : ** *.****.**:****:* *: * ::***:.: :.::* .* . **.:.:* *** . *.**:*:. ::************. *****.********::*.****::**.*:****:::**::* ****:.*:**::: **:***.** *..: :.. . :*: . .* **:* : :*.:. :** .*:.*** **: : **.* :* .: ::*. :* : * * ... :: .* . : ** *.: *:. *:**.****:********************:** :.:* * :* *:::.: *:.:***:*: **:***********************:**:***.*******************::*:**********:******************************:***** *******************:************************:***:*************:*******************:***:**:*::**:*******:* ******:******* **********.**** ********:**:********************.*****************:*****:***.*******************. *************.*********::******.*********:**********:***:******:**:***::****:*****:********.******:************", "identical_positions": 538, "similar_positions": 160, "identity": "68.02%" }, { "cls_id": "homologset.oma.811069", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P97570-1", "uniprot_id": "PLPL9_RAT", "id": "P97570-1", "name": "85/88 kDa calcium-independent phospholipase A2", "aln": "MQFFGRLVNTLSSVTNLFSNPFRVKEVSLADYASSERVREEGQLILLQNASNRTWDCVLVSPRNPQSGFRLFQLESEADALVNFQQYSSQLPPFYESSVQVLHVEVLQHLTDLIRNHPSWTVTHLAVELGIRECFHHSRIISCANSTENEEGCTPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNPQVLQLLGKNASAGLNQVNNQGLTPLHLACQMGKQEMVRVLLLCNARCNIMGPGGFPIHTAMKFSQKGCAEMIISMDSNQIHSKDPRYGASPLHWAKNAEMARMLLKRGCDVDSTSASGNTALHVAVTRNRFDCVMVLLTYGANAGARGEHGNTPLHLAMSKDNMEMVKALIVFGAEVDTPNDFGETPAFIASKISKLITRKALLTLLKTVGADYHFPFIQGVSTEQSSAAGPHPFFSLDRTQPPTISLNNLELQDLMPVSRARKPAFILSSMRDEKRSHDHLLCLDGGGVKGLVIIQLLIAIEKASGVATKDLFDWVAGTSTGGILALAILHSKSMAYMRGVYFRMKDEVFRGSRPYESGPLEEFLKREFGEHTKMTDVKKPKVMLTGTLSDRQPAELHLFRNYDAPEAVREPRCTPNINLKPPTQPADQLVWRAARSSGAAPTYFRPNGRFLDGGLLANNPTLDAMTEIHEYNQDMIRKGQGNKVKKLSIVVSLGTGKSPQVPVTCVDVFRPSNPWELAKTVFGAKELGKMVVDCCTDPDGRAVDRARAWCEMVGIQYFRLNPQLGSDIMLDEVSDAVLVNALWETEVYIYEHREEFQKLVQLLLSP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97819-1", "uniprot_id": "PLPL9_MOUSE", "id": "P97819-1", "name": "85/88 kDa calcium-independent phospholipase A2", "aln": "MQFFGRLVNTLSSVTNLFSNPFRVKEVSLTDYVSSERVREEGQLILLQNVSNRTWDCVLVSPRNPQSGFRLFQLESEADALVNFQQFSSQLPPFYESSVQVLHVEVLQHLTDLIRNHPSWTVTHLAVELGIRECFHHSRIISCANSTENEEGCTPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNPQVLQLLGKNASAGLNQVNNQGLTPLHLACKMGKQEMVRVLLLCNARCNIMGPGGFPIHTAMKFSQKGCAEMIISMDSNQIHSKDPRYGASPLHWAKNAEMARMLLKRGCDVDSTSSSGNTALHVAVMRNRFDCVMVLLTYGANAGARGEHGNTPLHLAMSKDNMEMVKALIVFGAEVDTPNDFGETPALIASKISKLITRKALLTLLKTVGADHHFPIIQGVSTEQGSAAATHPLFSLDRTQPPAISLNNLELQDLMPISRARKPAFILSSMRDEKRSHDHLLCLDGGGVKGLVIIQLLIAIEKASGVATKDLFDWVAGTSTGGILALAILHSKSMAYMRGVYFRMKDEVFRGSRPYESGPLEEFLKREFGEHTKMTDVKKPKVMLTGTLSDRQPAELHLFRNYDAPEAVREPRCNQNINLKPPTQPADQLVWRAARSSGAAPTYFRPNGRFLDGGLLANNPTLDAMTEIHEYNQDMIRKGQGNKVKKLSIVVSLGTGKSPQVPVTCVDVFRPSNPWELAKTVFGAKELGKMVVDCCTDPDGRAVDRARAWCEMVGIQYFRLNPQLGSDIMLDEVSDAVLVNALWETEVYIYEHREEFQKLVQLLLSP", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****************************:**.****************.************************************:*********************************************************************************************************************************************:*************************************************************************************:********** *************************************************************:************************:***:********.***..**:*********:*************:************************************************************************************************************************************************************. ***********************************************************************************************************************************************************************************************", "identical_positions": 789, "similar_positions": 16, "identity": "97.77%" }, { "cls_id": "homologset.oma.811782", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O70281-1", "uniprot_id": "TPST1_MOUSE", "id": "O70281-1", "name": "Protein-tyrosine sulfotransferase 1", "aln": "MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPARLENPKATVRAGLDIKANKTFTYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEVIVKHGEPAPYLCNKDPFALKSLTYLARLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLHIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKILENTRR--------VYKGEFQLPDFLKE--------------------------KPQTEQVE------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A4X1SY72-1", "uniprot_id": "A0A4X1SY72_PIG", "id": "A0A4X1SY72-1", "name": "Protein-tyrosine sulfotransferase", "aln": "MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPLRLESAKTTVPTVLDIKANKTFAYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLARLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKILENTRR--------VYKGEFQLPEFLKE--------------------------KPQTEQVE------------------------------------------------------------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "O60507-1", "uniprot_id": "TPST1_HUMAN", "id": "O60507-1", "name": "Protein-tyrosine sulfotransferase 1", "aln": "MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPVKLESTRTTVRTGLDLKANKTFAYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLSRLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKIIENTRR--------VYKGEFQLPDFLKE--------------------------KPQTEQVE------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V1ANA1-1", "uniprot_id": "A0A8V1ANA1_CHICK", "id": "A0A8V1ANA1-1", "name": "Protein-tyrosine sulfotransferase", "aln": "MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPARVESVRSTVRTGSDGNANKTFAYNKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILAVKQMWARSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLARIFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGFERCMLVHYEQLVLHPERWMRTLLKFLRIPWNQAVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVEALSKWVGKIPADVLQDMPVIAPMLAKLGYDPYANPPNYGKPDQKVVENTRRDDQQSRVPQYHRIVEWPALKRTTMTIQFQPSAVCRVTNHWTRAAQSHIQPGLECLQGWGILSLCLIAHLVGIASSLEIPNCTAFLWSYGFCFALFFTSSTAVCLLRHKAVGKQGVR", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9PTE6-1", "uniprot_id": "TPST1_DANRE", "id": "Q9PTE6-1", "name": "Protein-tyrosine sulfotransferase 1", "aln": "MIGKLKQNLLVACLVISSVTVFYLCRHAMDCHHRIEERSQPL-LSSLHATLRTGQN--LSTPFIYNKDMPLIFIGGVPRSGTTLMRAMLDAHPDVRCGEETRVIPRILAMKQMWSRSGREKMRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPANYLCNKDPFALKSLTYLAKIFPHAKFILMVRDGRASVHSMISRKVTIAGFDLSSYRDCLTKWNRAIETMYTQCLEA-ADKCLPVHYEQLVLHPEKWMRTLLRFLNIPWNDAVLHHEELIGKAGGVSLSKVERSTDQVIKPVNVEALSKWVGKIPLDVQRDMAVIAPMLARLGYDPHANPPNYGRPDPLVLDNTRR---------------LQKS------------------------------PEKPNPS------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:********:************* :***:*********** :.. ::*: : : ...* *:****************************:**************:****:**.:**:**********************:******** ****************:::**:***:*************************.*****************.**:*. .:*: ***********:******:**.****.:******:************************* ********** ** :**.*******:*****:*******:** :::**** * . ", "identical_positions": 280, "similar_positions": 50, "identity": "60.34%" }, { "cls_id": "homologset.oma.811784", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJS8-1", "uniprot_id": "TPST2_RAT", "id": "Q5RJS8-1", "name": "Protein-tyrosine sulfotransferase 2", "aln": "--------------MRLSVRKVLLAVGCALALVLAVQLGQQVLECRAVLGGVRSPR-RMQPEQEELVMLGADHVEYRYGKTMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWTKSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLARLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGRDKCLPVYYEQLVLHPRRSLKRILDFLGIAWSDTVLHHEDLIGKPGGVSLSKIERSTDQVIKPVNLEALSKWTGHIPRDVVRDMAQIAPMLARLGYDPYANPPNYGNPDPIVINNTHRVLKGDYKTPANLKGYFQVNQNSTSPHLGSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88856-1", "uniprot_id": "TPST2_MOUSE", "id": "O88856-1", "name": "Protein-tyrosine sulfotransferase 2", "aln": "--------------MRLSVRKVLLAAGCALALVLAVQLGQQVLECRAVLGGTRNPR-RMRPEQEELVMLGADHVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWTKSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLARLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGRDKCLPVYYEQLVLHPRRSLKRILDFLGIAWSDTVLHHEDLIGKPGGVSLSKIERSTDQVIKPVNLEALSKWTGHIPRDVVRDMAQIAPMLARLGYDPYANPPNYGNPDPIVINNTHRVLKGDYKTPANLKGYFQVNQNSTSPHLGSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3HTC1-1", "uniprot_id": "G3HTC1_CRIGR", "id": "G3HTC1-1", "name": "Protein-tyrosine sulfotransferase", "aln": "MRRAPCLGLGPWLGMRLSVRKVLLAAGCTLALLLALQLGQQVLECRAVLGGKRSAR-RMRPEQEELVMLGADQVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWSKSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLARLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGRDKCLPVYYEQLVLHPRRSLKRILDFLGIAWSDTVLHHEDLIGKPGGVSLSKIERSTDQVIKPVNLEALSKWTGHIPGDVVRDMAQIAPMLARLGYDPYANPPNYGNPDPIVINNTHRVLKGDYKTPANLKGYFQVNQNSTSPHLGSS", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "O60704-1", "uniprot_id": "TPST2_HUMAN", "id": "O60704-1", "name": "Protein-tyrosine sulfotransferase 2", "aln": "--------------MRLSVRRVLLAAGCALVLVLAVQLGQQVLECRAVLAGLRSPRGAMRPEQEELVMVGTNHVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWSKSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLSRLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGKEKCLPVYYEQLVLHPRRSLKLILDFLGIAWSDAVLHHEDLIGKPGGVSLSKIERSTDQVIKPVNLEALSKWTGHIPGDVVRDMAQIAPMLAQLGYDPYANPPNYGNPDPFVINNTQRVLKGDYKTPANLKGYFQVNQNSTSSHLGSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3SYY2-1", "uniprot_id": "TPST2_BOVIN", "id": "Q3SYY2-1", "name": "Protein-tyrosine sulfotransferase 2", "aln": "--------------MRLSMRRALLAAGLALALVLAVHLGQRVLECQAVLGGPRGPRRTMRPEQEDLMMVGADHVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWSKSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLSRLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGRDKCLPVYYEQLVLHPRRSLKVILDFLGIAWSDAVLHHEDLIGKPGGVSLSKIERSTDQVIKPVNLEALSKWTGHIPGDVLRDMAQIAPMLARLGYDPYANPPNYGNPDPIVINNTHRVLKGDYKTPANLKGYFQVNLNSTSSHLGSS", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1NGS3-1", "uniprot_id": "F1NGS3_CHICK", "id": "F1NGS3-1", "name": "Protein-tyrosine sulfotransferase", "aln": "--------------MRVTMRRVLLAVGSVVALMVTLHLGQQVLECQHVLS-KRRHR-LMRPENEELVMVDSNHVEYRYSKEMPLIFIGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWSKSGREKMRLDEAGVTDQVLDAAMQAFILEVIAKHGEPARYLCNKDPFTLKSSVYLSRLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLNSYRDCLTKWNKAIEVMYSQCLEIGRSRCLPVYYEQLVLHPEQSMHAIMKFLGISWSDTVLHHEELIGKPGGVSLSKIERSTDQVIKPVNMEALSKWIGHIPGDVLQDMAHIAPMLARLGYDPYANPPNYGHPDPLVVNNTHRVLKGDYKTPANLKGHLQVTQNTSSSH----", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:::*:.***.* .:.*:::::***:****: **. * * *:**:*:*:*:.:::*****.* *****:****************************************:******:*********:********************** ***************:**********************************.*****************:**:*:*:.:*************.:*:: *:.****:***:*****:*************************:****** **** **::***:******:*************:***:*:***:***************::**. *::*.* ", "identical_positions": 296, "similar_positions": 63, "identity": "75.7%" }, { "cls_id": "homologset.oma.812374", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A480ZG93-1", "uniprot_id": "A0A480ZG93_PIG", "id": "A0A480ZG93-1", "name": "Transmembrane protein 14C", "aln": "MQKDSGPLVPLHWIGFGYAALVASGGIIGYAKAGSVPSLAAGLLFGGLAGLGAYQLSQDPRN-------IWVFLVTSGTLAGIMGMRFYHSGKFMPAGLIAGASLLMVAK-LGIS---VLSKPHP--", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q3ZCI1-1", "uniprot_id": "TM14C_BOVIN", "id": "Q3ZCI1-1", "name": "Transmembrane protein 14C", "aln": "MPKDSGPLVPLHWLGFGYAALVASGGIIGYAKAGSVPSLAAGLLFGGLAGLGSYQLSQDPKN-------IWLFLVTSGTLAGIMGMRFYNSRKFMPAGLIAGASLLMVVK-LGIS---ALSKPHQ--", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q9CQN6-1", "uniprot_id": "TM14C_MOUSE", "id": "Q9CQN6-1", "name": "Transmembrane protein 14C", "aln": "MQKDSGPLMPLHYFGFGYAALVATGGIIGYAKAGSVPSLAAGLFFGGLAGLGAYQLSQDPRN-------VWVFLATSGTLAGIMGMRFYNSGKFMPAGLIAGASLLMVAK-VGIS---LLSSPHP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A061IDB4-1", "uniprot_id": "A0A061IDB4_CRIGR", "id": "A0A061IDB4-1", "name": "Transmembrane protein 14C", "aln": "MQKDSGPLVPLHYLGFGYAALVATGGIIGYAKAGSVPSLAAGLFFGSLAGYGAYQLSQDPRN-------VWVFLATSGTLAGIMGMRFYNSGKFMPAGLIAGASLLMVVK-LGIS---MLSSPQP--", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q0P436-1", "uniprot_id": "TM14C_DANRE", "id": "Q0P436-1", "name": "Transmembrane protein 14C", "aln": "--------MAVDWAGYGYAALVASGGVIGYVKAGSVPSLAAGLVFGGLAGFGAYQTSQDPGN-------IWVSLAASGTLAAIMGKRFYNSRKITPAGLIAGASVLMLAK-LGAG---MLQKPQKS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1K0-1", "uniprot_id": "TM14_DROME", "id": "Q9W1K0-1", "name": "Transmembrane protein 14 homolog", "aln": "--------MPVDWFGYVYAATVAAGGIMGYAKAGSIPSLGAGLAFGALLGYGAHLNSQDTPR-------PLLQLGTSLFLAGLMGARWNRSGKLMPAGMVCMLSVAALVKNLATYNRYLMPAGTKAP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9C6T7-1", "uniprot_id": "FAX5_ARATH", "id": "Q9C6T7-1", "name": "Protein FATTY ACID EXPORT 5", "aln": "--------MHDFCFTIPYGILLIVGGFIGYLKKGSIASLAGGAGTGLLVVLAGFISLKAFEKKKTSLLATLLETVIAAALTFVMGQRFLQTQKIMPAALVAGISALMTCFYVYKIATGGNHIPPKAE", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. : **.:** * **:.**..* * * ... : . : : *: :** *: .: *: **.::. * : ", "identical_positions": 21, "similar_positions": 27, "identity": "16.54%" }, { "cls_id": "homologset.oma.812376", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZUB4-1", "uniprot_id": "D3ZUB4_RAT", "id": "D3ZUB4-1", "name": "Transmembrane protein 14A", "aln": "MDLIGFGYAALVTIGSVL------------------------------GYKRRG----GVPSLIAGLSVGLLAGYGAYRVSNDKRD-VKVSLFTAFFLATIMGVRFKRSKKVMPAGLVAGLSLMMILRLVLLLL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56983-1", "uniprot_id": "TM14A_MOUSE", "id": "P56983-1", "name": "Transmembrane protein 14A", "aln": "MDLIGFGYAALVTIGSVL------------------------------GYKRRG----GVPSLIAGLSVGLLAGYGAYRVSNDRRD-VKVSLFTAFFLATIMGVRFKRSKKVMPAGLVAGLSLMMILRLVLLLL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56982-1", "uniprot_id": "TM14A_BOVIN", "id": "P56982-1", "name": "Transmembrane protein 14A", "aln": "MDLIGFGYAALVTFGSIL------------------------------GYKRRG----GVLSLIAGLFVGFLAGYGAYRVSNDKRD-VKLSLFTAFFLATIMGVRFKRSKKIMPAGLVAGLSLLMILRLVLLLL--", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "P56984-1", "uniprot_id": "TM14A_PIG", "id": "P56984-1", "name": "Transmembrane protein 14A", "aln": "MDLIGFGYAALVTFGSIL------------------------------GYKRRG----GVPSLIAGLFVGFLAGYGAYRVSLDKRD-VKLSLFTAFFLATIMGVRFKRSKKIMPAGLVAGLSLLMILRLVLLLL--", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q9Y6G1-1", "uniprot_id": "TM14A_HUMAN", "id": "Q9Y6G1-1", "name": "Transmembrane protein 14A", "aln": "MDLIGFGYAALVTFGSIF------------------------------GYKRRG----GVPSLIAGLFVGCLAGYGAYRVSNDKRD-VKVSLFTAFFLATIMGVRFKRSKKIMPAGLVAGLSLMMILRLVLLLL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8C2LSA4-1", "uniprot_id": "A0A8C2LSA4_CRIGR", "id": "A0A8C2LSA4-1", "name": "Transmembrane protein 14A", "aln": "MDLVGFGYAALVTVGSIL------------------------------GYKRRG----GVPSLIAGLSVGFLAGYGAYRVSNDKRD-VKVSLFTAFFLATIMGVRFKRSKKIMPAGLVAGLSLVMILRLVLLLL--", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "A0A8V0X4T3-1", "uniprot_id": "A0A8V0X4T3_CHICK", "id": "A0A8V0X4T3-1", "name": "", "aln": "MRDRKNGLVQVCSSKIILPKLQVLVDPHPHPLIEQTLPVMLCKRMTGRGYRNAASIHTGKISLAAGLTFGSVAGYGAYCVTRDPRN-VKISLFSAFLLTVIMGMRFKRSKKLMPAGLVACLSLLMILRLVFMLL--", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "C7G056-1", "uniprot_id": "C7G056_DICDI", "id": "C7G056-1", "name": "", "aln": "MTTLVYAYAILLAIGGLI------------------------------GYLKAN----SMPSLIMGLLSGLLVGYSANLTTTNKKNGTQLTMALSLVLLIIMGMRFVNSGKFFPAGLVSVFSAIILVKSFLSLSQM", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . : : :: ** . . ** ** * :.**.* .: : :: .:::: ::.* ***:** .* *.:*****: :* ::::: .: * ", "identical_positions": 26, "similar_positions": 37, "identity": "19.12%" }, { "cls_id": "homologset.oma.812378", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NUH8-1", "uniprot_id": "TM14B_HUMAN", "id": "Q9NUH8-1", "name": "Transmembrane protein 14B", "aln": "MEKPLFPLVPLHWFGFGYTALVVSGGIVGYVKTGSVPSLAAGLLFGSLAGLGAYQLYQDPRNVWGFLAATSVTFVGVMGMRSYYYGKFMPVGLIAGASLLMAAKVGVRMLMTSD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0R701-1", "uniprot_id": "M0R701_RAT", "id": "M0R701-1", "name": "Transmembrane protein 14C", "aln": "MQKDSGPLVPLHYYGFGYAALVATGGIIGYAKAGSVPSLAAGLFFGGLAGLGAYQLSQDPRNVWVFLA-TSGTLAGIMGMRFYNSGKFMPAGLIAGTSLLMVAKLGLSMLSSSHP", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* ******::****:***.:***:**.*:**********:**.********* ******* *** ** *:.*:**** * *****.*****:****.**:*: ** :*. ", "identical_positions": 81, "similar_positions": 21, "identity": "70.43%" }, { "cls_id": "homologset.oma.812379", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q924P2-1", "uniprot_id": "TM14C_RAT", "id": "Q924P2-1", "name": "Transmembrane protein 14C", "aln": "-----------------------------------------------------------------MQKDSGPLVP------LHYYGFGYAALVATG--GIIGYAKAGSVPSLAAGLFFGGLAGLGAYQLSQDPRNVWVFLATSGTLAGIMGMRFYNSGKFMPAGLIAGASLLMVAP-GVAKIQEITTMP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P0S9-1", "uniprot_id": "TM14C_HUMAN", "id": "Q9P0S9-1", "name": "Transmembrane protein 14C", "aln": "-----------------------------------------------------------------MQ-DTGSVVP------LHWFGFGYAALVASG--GIIGYVKAGSVPSLAAGLLFGSLAGLGAYQLSQDPRNVWVFLATSGTLAGIMGMRFYHSGKFMPAGLIAGASLLMVAKVGVSMFNRPH---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0Y3L9-1", "uniprot_id": "A0A8V0Y3L9_CHICK", "id": "A0A8V0Y3L9-1", "name": "Transmembrane protein 14C", "aln": "PRSAPLHGGHGRAPLLRTGSPRAGPTAAFPADPEVHSLAWGSGRPSSRKPLPRQKNILVIISSPAPRLERTPLPPSLFSTFQHGRGLDRVRLRRSGDIGRVHWLRQSSVPSLVAGLLFGSLAGLGAYQLSQNPSNVWISLITSGTLTAVMGTRFYNSGKFMPAGLIAGVSLLMVGRLALKMLEKPHEK-", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: * * *:. . * :* * : : : .*****.***:**.***********:* ***: * *****:.:** ***:************.*****. .: ::. ", "identical_positions": 59, "similar_positions": 28, "identity": "31.22%" }, { "cls_id": "homologset.oma.813836", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BTE0-1", "uniprot_id": "SDHF4_MOUSE", "id": "Q8BTE0-1", "name": "Succinate dehydrogenase assembly factor 4, mitochondrial", "aln": "MVSTTLSVSR---MTFVWRAARPSLLNHSLRKMS-YQEGKPEPAKQALKKSKLPLGRFDSLEDSPEEREPLQKFPDDVNPVTKEKGGPKGPEPTRYGDWERKGRCIDF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3GUE2-1", "uniprot_id": "G3GUE2_CRIGR", "id": "G3GUE2-1", "name": "Succinate dehydrogenase assembly factor 4, mitochondrial", "aln": "MVSTIFAGSL---VASVWRATRSSLLKNSLRKVS-YQEGKSEPVKQPLKKSKLPVGRFDAPEDLHMEREPLKKFPGDVNPVTKEKGGPRGPEPTRYGDWERKGRCIDF", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q5VUM1-1", "uniprot_id": "SDHF4_HUMAN", "id": "Q5VUM1-1", "name": "Succinate dehydrogenase assembly factor 4, mitochondrial", "aln": "MTPSRLPWLLSWVSATAWRAARSPLLCHSLRKTSSSQGGKSELVKQSLKKPKLPEGRFDAPEDSHLEKEPLEKFPDDVNPVTKEKGGPRGPEPTRYGDWERKGRCIDF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*..: :. : .***:*..** :**** * * **.* .**.***.*** ****: ** *:***:***.************:*******************", "identical_positions": 68, "similar_positions": 20, "identity": "62.96%" }, { "cls_id": "homologset.oma.813972", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q32PY6-1", "uniprot_id": "HENMT_RAT", "id": "Q32PY6-1", "name": "Small RNA 2'-O-methyltransferase", "aln": "METAENIPC-SMLGDNFKEVCAEKVIRFRPPLYKQRYQFVRDLVDRHEPKKVADLGCGDTKLLKLLKIYP-CIQLLVGVDINEEKLHSNGHRLSPYLGEFVKPRDLDLTVTLYHGSVVERDSRLLGFDLITCIELIEHLDSDDLARFPEVVFGYLSPAMVVISTPNAEFNPLFP-TVTLRDADHKFEWSRMEFQTWASQVANCYNYCVEFTGVGTPPAGSEHVGYCTQIGVFRKNGGKLSEPSA-SQQRDQHVYKAVYTTSYPSLQQEKVLKFVLVGELLIQVDRLRLRHQRMLREQEKERGPKPWYTDSSPAPHLLLGAVFTEAEKARIENSPKPFCEGEKFYIPLQRLLTYPKLHRLCADEDRMRSLIADS--VCLSSDGSAVVVDLHNSWDYRPEDN-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CAE2-1", "uniprot_id": "HENMT_MOUSE", "id": "Q8CAE2-1", "name": "Small RNA 2'-O-methyltransferase", "aln": "MEMAESIPCNSVVGGNFKEVSPEKVIRFKPPLYKQRYQFVRDLVDRHEPKKVADLGCGDAKLLKLLKIYP-CIQLLVGVDINEEKLHSNGHRLSPYLGEFVKPRDLDLTVTLYHGSVVERDSRLLGFDLITCIELIEHLDSDDLARFPDVVFGYLSPAMVVISTPNAEFNPLFP-TVTLRDADHKFEWSRMEFQTWALHVANCYNYRVEFTGVGTPPAGSEHVGYCTQIGVFTKNGGKLSKPSV-SQQCDQHVYKPVYTTSYPSLQQEKVLKFVLVGELLIQVDRLRLRYQRMLRDREKDRGPKPGDMDSCPAPHLLLGAVFTEAEKARIESSPKPFCEGEKFYIPLQRLLTYPKLHRLCADEDRVRSLIADS--VCLSSDGSAVVVDLHNSWDYRPEEN-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T8I9-1", "uniprot_id": "HENMT_HUMAN", "id": "Q5T8I9-1", "name": "Small RNA 2'-O-methyltransferase", "aln": "ME-ENNLQCSSVVDGNFEEVPRETAIQFKPPLYRQRYQFVKNLVDQHEPKKVADLGCGDTSLLRLLKVNP-CIELLVGVDINEDKLRWRGDSLAPFLGDFLKPRDLNLTITLYHGSVVERDSRLLGFDLITCIELIEHLDSGDLARFPEVVFGYLSPSMIVISTPNSEFNPLFP-SVTLRDSDHKFEWTRMEFQTWALYVANRYDYSVEFTGVGEPPAGAENVGYCTQIGIFRKNGGKATESCL-SEQHDQHVYKAVFTTSYPSLQQERFFKLVLVNEVSQQVESLRVSHLPRRKEQAGERGDKPKDIGGSKAPVPCFGPVFTEVEKAKIENSPTPFCVGDKFFVPLQRLLAYPKLNRLCANEEMMRSVIADS--IPLSSDGSAVVADLRNYFDEQFEF------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A480TM63-1", "uniprot_id": "A0A480TM63_PIG", "id": "A0A480TM63-1", "name": "Small RNA 2'-O-methyltransferase", "aln": "--MAEDKECHSVVE----EVPSKRIIKFNPPLYKQRYQFVKNLVEQHQPQKVADLGCGDLSLLSILKYLK-CVTELVGVDINEGRLKWNGSRLSPCVGDHLDPRELDLVITLYHGSVLEKDCRLLGFDLVTCIELIEHFDSEDLARFPEVVFGYMSPAMIVISTPNSDFNSLFP-LSVFRDSDHKFEWSRVQFQTWALDVANRYSYSVEFTGVGEPPAEAEDVGYCTQIGVFRKKE-KTTESDV-LEHPGERVYEVVYTTSYPSLQQINYRRRVVVYLVYREVNKMRLRYQVSLRRHELEPESTDPDDPRRKFISGLPVHTPTEADKA-MAMTPQPFCIGDKFYVPLKRIIAYPRLGYLCGNVQELRELLADS--IELNCDASAVKVDLYHCSDYC---------------------------------------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "E1BVR9-1", "uniprot_id": "HENMT_CHICK", "id": "E1BVR9-1", "name": "Small RNA 2'-O-methyltransferase", "aln": "--MDKNFEGKQFTG----------VIKFTPPLYKQRYEFVQDLVRKYEPKKVADLGCADCTLLWMLKFCS-CIEVLAGLDICETVMKEKMHRLTPLPADYLEPSERSLIVTLHQGSVAHKDPCMLGFDLVTCIELIEHLQESELEKFPEVVFGFMAPNMVVISTPNSEFNTLLPGVTVFRHPDHKFEWDRAQFQSWAQDTAERYEYSVEFTGVGSPPTGMEDVGFCTQIGVFVKKYPQTREPVQ-REKPTEAAYKTVFKAVYPSLKDEKYLQNAVVSEVMFRAQLIKRSLLDHLLSECEEYNDDP--TERKLKLQCSVNCFSEDVETLAVEKSTEPFVSGNVIYIPLRKIFSVPKVNQLCGTFEKFCRLITGK--VTLNSDSSALMLDTENEEN-----------------------------------------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q568P9-1", "uniprot_id": "HENMT_DANRE", "id": "Q568P9-1", "name": "Small RNA 2'-O-methyltransferase", "aln": "----------------------MTATPFSPPLYMQRYQFVIDYVKTYRPRKVIDFGCAECCLLKKLKFHRNGIQLLVGVDINSVVLLKRMHSLAPLVSDYLQPSDGPLTIELYQGSVMEREPCTKGFDLVTCVELIEHLELEEVERFSEVVFGYMAPGAVIVTTPNAEFNPLLPGLRGFRNYDHKFEWTRAEFQTWAHRVCREHGYSVQFTGVGEAAGHWRDVGFCTQIAVFQRNFDGVNRSMSNAEHLEPSVYRLLYRVVYPSLCDNNIYQKTLINEVLYEAQHLRQQWLIRENMN----------NNAHFYSPPLMEALHHGAEGNACEQQP-VYQQGGIICVPLARVWSCPRVQALCGSLQRLREKLLEDERVRMSADGSALNLPADDDDDNVEEEEEEEEEENQQNVKAVSGAVNNMEEDWDRELGSYGDE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **** ***:** : * :.*:** *:**.: ** ** : *.*:** . : . *:* .:.:.* : * : *::*** .:: ****:**:*****:: :: :*.:****:::* ::::***::**.*:* :*. ****** * :**:** ... : * *:***** .. ..**:****.:* :: .. :: .*. :: . **** : . : .:: : ..: :: . .: . : * : :** :: : *:: **. : . : . : :..*.**: . : ", "identical_positions": 97, "similar_positions": 111, "identity": "22.3%" }, { "cls_id": "homologset.oma.814335", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q642A4-1", "uniprot_id": "CH082_RAT", "id": "Q642A4-1", "name": "UPF0598 protein C8orf82 homolog", "aln": "MWPPCGAMRNLALVLARSQRARACSGNERVSYTQGQSPEPRTREYFYYVDHQGQLFLDDSKMKNFITCFKDLQFLVTFFSRLRPNHSGRYEASFPFLSLCGRERNFLRCEDRPVVFTHLLASDSESPRLSYCGGGEALAIPFEPARLLPLAANGRLYHPAPERAGGVGLVRSALAFELSACFEYGPN---SPTVPSHVQWQGRRIALTMDLAPLLLAAPPP-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VE95-1", "uniprot_id": "CH082_MOUSE", "id": "Q8VE95-1", "name": "UPF0598 protein C8orf82 homolog", "aln": "MWPPSGAVRNLALVLARSQRARTCSGVERVSYTQGQSPEPRTREYFYYVDHQGQLFLDDSKMKNFITCFKDLQFLVTFFSRLRPNHSGRYEASFPFLSLCGRERNFLRCEDRPVVFTHLLASDSESPRLSYCGGGEALAIPFEPARLLPLAANGRLYHPAPERAGGVGLVRSALAFELSACFEYGPS---SPTVPSHVHWQGRRIALTMDLAPLLPAAPPP-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P1X6-1", "uniprot_id": "CH082_HUMAN", "id": "Q6P1X6-1", "name": "UPF0598 protein C8orf82", "aln": "MWPPCGTLR--TLALARSRGARACSGDGGVSYTQGQSPEPRTREYFYYVDHQGQLFLDDSKMKNFITCFKDPQFLVTFFSRLRPNRSGRYEAAFPFLSPCGRERNFLRCEDRPVVFTHLLTADHGPPRLSYCGGGEALAVPFEPARLLPLAANGRLYHPAPERAGGVGLVRSALAFELSACFEYGPG---APALPSHVRWQGRRLALTMDLAPLLLAARSP-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RSQ0-1", "uniprot_id": "F1RSQ0_PIG", "id": "F1RSQ0-1", "name": "", "aln": "MWATRGALQAWTVGWARSSGSRAYGGGQGVSYTQGQSPEPRTREYFYYVDHQGQLFLDDSKMKNFITCFKDPQFLVFFFSRLRPNRSGRYETSFPFLSPCGRERNFLRCEDRPVVFTHLLAAGPEPPRLSYCGGGEALTVPFEPARLLPLAANGRLYHPAPERAGGVGLVRSALAFELSACFEYAPG---APELPSHVRWQGCRFALTMDLAPLLPAAPPR-----", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "B8JMG6-1", "uniprot_id": "B8JMG6_DANRE", "id": "B8JMG6-1", "name": "", "aln": "-------MRFVKRIFSRQCG-LFCRNVS--SYTQGQSPEARIREYFYYIDHQGQLFLDDTKVKNFVTCFKDQHFLVFFFSRLKVNQSGRYQQDFPFVSLCGRERNFLRCEDQPIVFTHLFSEVGLEDRLSYCGGGAKLSVPFRPQSLFMHPDSGRVYHPGPERTGGAGLLRSALAIEISAHFGYDTGQDGTAAQPTHFTWAGRRHALSKELEKHFPVQKDECMKIR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :*. . *********.* ******:**********:*:***:***** :*** *****: *:****: ***:* ************:*:*****:: ******** *::**.* *: . .**:***.***:**.**:*****:*:** * * .. :. *:*. * * * **: :* : . ", "identical_positions": 114, "similar_positions": 42, "identity": "50.44%" }, { "cls_id": "homologset.oma.814371", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q642B8-1", "uniprot_id": "Q642B8_RAT", "id": "Q642B8-1", "name": "", "aln": "MVLKAFFPTCCASADSGLLVGRWVPGQNSAVILAVVHFPFIPIQVKELLAQVQKASQVQVTVLGTWCHRQQEPEESLGKFLEGLGAIFSHNPWLQLCREKGTRFWSCKATY--------HQMSSTLDTPTEDQVMLIFYDQRKLLLSWLHPPPVLPDCQIGDSTASTGGLADIFDTVARSEVLFRNDQFDEGPVRLSHWQSEGVEASILVELAKRASGPVCLLLASLLSLISAASACRLWKLGPLAFIRSKLSTCEQLQHRLKHLSFIFSTEKAQSPMQLMRKANMLVSVLLDVALGLLLLSWLHSNNRIGQLANALVPVADRVAEELQHLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHLWISYIHLMSPFIEHILWHVGLSACLGLTVALSIFSDIIALLTFHIYCFYVYGARLYCLKIYGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILVFLLPTTALYYLVFTLLRLLVITVQGLIHLLVDLINSLPLYSLGLRLCRPYRLAAG---VKFR-------------------------------VLEKEAGRP--LRLLMQINP---------------LPYSHVVHTYRLPSCGCHPKHSWGTLCRKLFFGELIYPWRQREDKQD--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYT7-1", "uniprot_id": "PIGQ_MOUSE", "id": "Q9QYT7-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q", "aln": "MVLKVFFPTCCASADSGLLVGRWVPGQSSAVILAVVHFPFIPIQVKELLAQVQKASQVPVAVLGTWCHRQQEPQESLGNFLEGLGTIFSHDPWLQLCRERGTRLWSCKATY--------PQMSNPLDMHPEEQVMLIFYDQRKLLLSWLHPPPVLPACQMGDTTASTGGLADIFDTVARSEVLFRNDQFDERPVRLSHWQSEGVEASILVELAKRASGPVCLLLASLLSLISAASACRLWKLWPLSFIRSKLSTCEQLHHRLKHLSFIFSTEKAQNPMQLMRKANMLVSVLLDVALGLLLLSWLHSNNRIGQLANALVPVADRVAEELQHLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHLWISYIHLMSPFIEHILWHVGLSACLGLTVALSIFSDIIALLTFHIYCFYVYGARLYCLKIYGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILVFLLPTTALYYLVFTLLRLLVITVQGLIHLLVDLINSLPLYSLGLRLCRPYRLAAG---VKFR-------------------------------VLEKEAGRP--LRLLMQINP---------------LSYNHVMHIYRLPRCGCHPKHSWGTLCRKLVFGELIYPWRQREDKQD--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3HBT3-1", "uniprot_id": "G3HBT3_CRIGR", "id": "G3HBT3-1", "name": "", "aln": "MVLKAFFPTCCASADSGLLVGRWIPEQNSAVILAVAHFPFIPIQVKELLAQVHKASQVQVAVLGTWCHRRQEPEESLGHFLEGLGAIFSHDPWLQLCRERGTRFWSCKATY--------HQLQG---TPTEDQVMLIFYDQRKLLLSWLHPPTALPDCQAGETTASTGGLADIFDTVAHSEVLFRNDQFDEGPVRLSHWQSEGMEASILVELAKQASGPVCLLMASLLSLLSAASACRLWKLWPLAFIRSKLSTCEQLQHRLKHLSFIFSTQKAQSPMQLMRKANMLVSVLLDVALGLLLLSWLHSNNRIGQLANALVPVADRVAEELQHLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHLWISYIHLMSPFIEHILWHVGLSACLGLTVALSILSDIIALLTFHIYCFYVYGARLYCLKIYGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILVFLLPTTALYYLVFTLLRLLVITVQGLIHLLVDLINSLPLYSLGLRLCRPYRLAAG---VKFR-------------------------------VLEQEAGRP--LRLLMQINP---------------LPYSHVVHTYRLPSCGCHPKHSWGSLCRKLFFGELIYPWRQREDKQD--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q9BRB3-1", "uniprot_id": "PIGQ_HUMAN", "id": "Q9BRB3-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q", "aln": "MVLKAFFPTCCVSTDSGLLVGRWVPEQSSAVVLAVLHFPFIPIQVKQLLAQVRQASQVGVAVLGTWCHCRQEPEESLGRFLESLGAVFPHEPWLRLCRERGGTFWSCEATH--------RQAPTAPGAPGEDQVMLIFYDQRQVLLSQLHLPTVLPDRQAGATTASTGGLAAVFDTVARSEVLFRSDRFDEGPVRLSHWQSEGVEASILAELARRASGPICLLLASLLSLVSAVSACRVFKLWPLSFLGSKLSTCEQLRHRLEHLTLIFSTRKAENPAQLMRKANTVASVLLDVALGLMLLSWLHGRSRIGHLADALVPVADHVAEELQHLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHLWISYIHLMSPFVEHILWHVGLSACLGLTVALSLLSDIIALLTFHIYCFYVYGARLYCLKIHGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILLFLLPTTALYYLVFTLLRLLVVAVQGLIHLLVDLINSLPLYSLGLRLCRPYRLADKPTALQPRGAHLPPPQLWLPPQALLGRPVPQAVPWGAHLPLEAERGQAGLRELLARLAPPHGHSQPSALPGWHQLSWRMSCALWTLLCAPEHGRPCYHTLGLEVIGSEQMWGWPARLAALHHWHCLPWDPLPTCCGHHGGEHSNPRCPEHCPMPTLCTQVQRVRPPQQPQVEGWSPWGLPSGSALAVGVEGPCQDEPPSPRHPLAPSAEQHPASGGLKQSLTPVPSGPGPSLPEPHGVYLRMFPGEVAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0ZAD1-1", "uniprot_id": "A0A8V0ZAD1_CHICK", "id": "A0A8V0ZAD1-1", "name": "", "aln": "MVLKVFFPSCCSSAESGILIGRWIPEQSSAVILAVVHFPFIPVQVKQYLREVQQVTKVSVSVLGSWNNSKQEKEESLSEFLEDLGTIFSHEPWIQISKEGDSKFWNCSTLQ--------KQPDN----HREEEIILVYYDQRKVMLSHLHPPSDTAD--LGAEDASK--LSAIFNTVASSKVLFMTDRYDDGPIKMTHWQSDGIEASIIVELMKQASVPACMLLTFLLSLVSGVCNSRVLKFWPLSFLWSKLSTCEQLGHRLQHLQVISSSKKAQNQTQLMRKANIFVSLLIDVALGILLMSWLYRKNQIGHLADTLIPVADHVAEELQDLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHLWISYIHLMSPFIEMILWYVGLSACLGLTVALCILSDIIALLTFHIYCFYVYGARLYCLKIYGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILLFLLPTTALYYLVFTLLCLLVVIVQGLIHLLVDLIDSLPLYSIILRFCRSYRLAAG---VKFR-------------------------------VLEQQDGKP--LRLLMQINP---------------LSYGSVVQTYRLPTYSCYPKDSWTSLCKKLFLGELIYPWKHKGEKQD--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "F1QHT3-1", "uniprot_id": "F1QHT3_DANRE", "id": "F1QHT3-1", "name": "", "aln": "MVLKIFFPQCCNTADSGLLVGRWIPGHNSAVVLAVVHYPFIPGQVKKYLSEIQSQTQVDLAVLGSWSMPK-EGQEGLDSFLKDLSTIFPQKCWLQLSREIGKRGFTCRVVQNNGMLLQDKEQKSDVDGSEEDKIILVHYDQRKVMLSQLHP--VQEADQKSEIEPSE--LRLVFQTVAQSQPLFFLDKYDDGPLKLTHWQSEGREASIIAELLKQASVPVCICLTWLLSLWLWFCSFRILNIPPVKFITSKLSTCVQSGYRAVHFKTVFSPKKADTHMDFMRKANIFVSFLVDIAFGLLLISWLYRENRISKLANTLVPVADHVAKELQQLLEWLMGAPAGLKMNKALDQVLGRFFLYHIHLWISYIHLMSPFIERILWYVGLSACLGLTFALSILSDIVALLTFHIYCFYVYGARLYCLKIYGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILLFLLPTTALYYLVFTLLRLVVVLFQGVIHLSVDFINSFPLFAIGLRICRPYRLAEG---VKFK-------------------------------VLCEESGSP--LHLMMEINP---------------LKCSSVLQRYRTPTYSCYPKDSWAALCKKLFVGELIYPWKQKTDKTD--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** *** ** :::**:*:***:* :.***:*** *:**** ***: * :::. ::* ::***:* : * :*.*. **:.*.::*.:. *:::.:* . :.* . : *::::*:.****:::** ** . .* * :*:*** *: ** *::*: *::::****:* ****:.** ::** * *: :: **** . *: :: *: *: ****** * :* *: : *..**:. ::***** ..*.*:*:*:*::*:***: ..:*.:**::*:****:**:***.**:************:***************************:* ***:**********.**.::***:**********************:*****************************************:**************** *:*: .**:*** **:*:*:**::: **:**.**** :: : * : * . .*: .: * * : : : .: :* ::. .* :: * : . ", "identical_positions": 297, "similar_positions": 153, "identity": "38.67%" }, { "cls_id": "homologset.oma.814396", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O22763-1", "uniprot_id": "BZP10_ARATH", "id": "O22763-1", "name": "Basic leucine zipper 10", "aln": "MN----SIFSIDDFSDPFWETPPIPLNPDSSKPVTADEVSQSQPEWTFEMFLEEISSSAVSSEPLGNNNNAIVGVSSAQSLPSVSG---------------------------QNDFEDDSRFRDRDSGNLDCAAPMTTKTVIVDSDDYRRVLKNKLETECATVVSLRVGSVKPEDSTSSPETQLQPVQSSPLTQGELGVTSSLPAEVKKTGVSMKQVTSGSSREYSDDEDLDEENETTGSLKPEDVKKSRRMLSNRESARRSRRRKQEQTSDLETQVNDLKGEHSSLLKQLSNMNHKYDEAAVGNRILKADIETLR-AKVKMAEETVKRVTGMNPMLLGRSSGHNNNNRMPITGNNRMDSSSIIPAYQPHSNLNHMSNQNIGIPTILPPRLGNNFAAPPSQTSSPLQRIRNGQNHHVTPSANPYGWNTEPQNDSAWPKKCVD", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q55E93-1", "uniprot_id": "BZPE_DICDI", "id": "Q55E93-1", "name": "Probable basic-leucine zipper transcription factor E", "aln": "MDDQQLTIQQIQQLHMLLQQQQQQQQQQQQQQQQQQQQLQQQNFQLTPQNFQIPVNNNNNNNNNSNNNNNNETAFNITSQNNSIAANLNNDTNIINTTTTTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTAPNQKFPTRKYKKQKDKLAELGIDVELSKKPTAAVKKKPPAKKSAKNAASQPTSPTLSTTNTSSAFTTAVLDTKKRKNQELLDYSDNSEESDSDEEDFENGDNENGDFPGGGDRKNRRLLKNREAAQLFRQRQKEYINSLESKASSLEASNTTALSKVSHLTEENQLMKDKVRYLKNFVKQAVSISLPMSVVNQDNINNLNNNLNGLQNQQNNNNNNNNNNNNNNNNN-----NNNNNNNNNNNNQNN---------FNNNNNNNINNNITFNNNNNNNSNNNNSNNIDSLLFNLPPD-----------", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :* .*::: : : : :..: :::.*.: : * : * :... ..: .**** .... :.. *::. :*: :::.. .:.:..* : :** . .. ..: :: : ::.* :. : * . * ..::. :. . : . *: . ..*::: *:.. .: : :..*... **:**::: :: .*.: . :*.**:*.***:*: *:*::* ..**::...*:..::: *.::*::..: : * ** :: .: *: . ..:..:* * * .. :****. ..**. :.. : :.* *: .*** :.** .:. : :. .*..*:: : . :. :* *: ", "identical_positions": 67, "similar_positions": 186, "identity": "15.12%" }, { "cls_id": "homologset.oma.814413", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q91WC9-1", "uniprot_id": "DGLB_MOUSE", "id": "Q91WC9-1", "name": "Diacylglycerol lipase-beta", "aln": "------------------------------------------------------------------MPGMVLFGRRWSLASDDLVFPGSFELFLRVLWWIVSLTLYLTHRRRLDCPGGVLLSTYLIVLLVLLAVIICTVLAIVCVSMRGTICNPGPRKSMSKLLYIRLALFLPEMVWASLGAAWVAKG-IQCDRTVVIGIIATVIVSWIVIAATMVTIIFVFDPLGGKMAPYPPCIPEHLDSNSSNRLLTGLKTAAKSVWETRVQFCCCCVGQDDNTRVAFSSTADLFSTYFSDTDLVPSDIAAGFTLLHQQQDNISHSREPPEVVTHTPGQPQETELDAEVENCHHYMPFAAAAYGWPLYIYRNPFTGLCRIGGDCCRARDIEYDAVEGDQHNCHFASILKTTGLQYRDFIHISFHDKVYELPFIVVLDHRKESVVVAVRGTMSLQDVLTDLSAESETLELGIELQDCVAHKGIAQAARYIHRRLVNDGILSQAFSVAPEYQLVLVGHSLGAGAAALLAIMLRGAYPQVRAYAFSPPRGLLSKSLYEYSKDFVVSLILGMDVIPRLSVTNMEDLKRRILRVIANCNKPKYKILLHGCWYGLFGGSPDNFPTELDEGTQGALTQPLLGEQTLLTRYSPGYC-SSDSPLDSPTKYPTLYPPGRIIHLEEEGGSGRFGCCSAAQYRARWAHEAEFSKILIGPKMLIDHMPDVMIRALDRVLADR-TACVSCPGQGGSSVP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C1S9-1", "uniprot_id": "DGLB_RAT", "id": "P0C1S9-1", "name": "Diacylglycerol lipase-beta", "aln": "------------------------------------------------------------------MPGMVLFGRRWSLASDDLVFPGSFELFLRVLWWIASLTLYLMHRRKLDCPGGVLLSTYLIVLLVLLAVIIGIVLAIVCVSMRGTICNPGPRKSMSKLLYIRLALFLPEMVWASLGAAWVAKG-IQCDRTVVIGIIATVIVSWIVIAATMVTIVFVFDPLGGKMAPYPPCIPEHLDSNSSNHLLTGLRTAAKSVWETRVQCCCCCIGQDDNTRVAFSSTADLFSTYFSDTDLVPSDIAAGFTLLHQQQDKISHSREPSEVVTHTPGQPQETELDAEVENCHHYMPFSPVCSPWPVCVLNSSRVELCRTGNNFCRGRDIEYDAVEGDEHHCHFASILKTTGLQYRDFIHVSFHDKVYELPFIVVLDHRKESVVVAVRGTMSLQDVLTDLSAESENLELDIELQDCVAHKGIAQAARYIYRRLVNDGILSQAFSVAPEYRLVVVGHSLGAGAAALLAIMLRGAYPQVRAYAFSPPRGLLSKSLFEYSKDFVVSLILGMDVIPRLSVANMEDLKRRILRVIANCNKPKYKILLHGCWYSVFGGSPDNFPTELDEGNQGALTQPLLGEQTLLTRCSPGYC-SGDSPLDSP-KYPTLYPPGRIIHLEEEGGSGRFGCCSAAQYRARWAHETEFSKILIGPKMLIDHMPDVMIRALDRVVADR-TACVSCPGQGGSNVP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8C2MEG3-1", "uniprot_id": "A0A8C2MEG3_CRIGR", "id": "A0A8C2MEG3-1", "name": "Diacylglycerol lipase-beta", "aln": "------------------------------------------------------------------MPGMVLFGRRWSLASDDLVFPGSFELFLRVLSWIASLTLYLVHRRKLDCPGGVLLSTYLIVLLVLLAVIICTVLAMVCVSMRGTICNPGPRKSMAKLLYVRLALFLPEMVWASLGAIWVAKG-IQCDKTVLIGIMTTVIVSWIVMAATMVTIIFVFDPLGGKMAPHPPGCPEHLDSNNSNQLLTGLKTAAKSVWETRVMFCCCCVGQDDNARVAFSSAADLFSTYFSDTDLVPSDIAAGFTLLHQQQDNINNSLEPQEVITHFPGQSQEADLDAEVENCHHYMPFAAAAYGWPLYIYRNPFTGLCRIGGDCCRSRETEYDAVEEDQHNCHFASILKTTGLQYRDFIHISFHDKVYELPFIVVLDHRKEAVVVAVRGTMSVQDVLTDLSAESENLELDIELQDCVAHKGIAQAARYVYHRLVNDGILSQAFSVAPEYRLVLVGHSLGAGAAALLAIMLRRTYPQVRAYAFSPPRGLLSKSLYEYSKDFIVSLILGMDVIPRLSVTNMEDLKRRILRVIANCNKPKYKILLHGCWYGLFGGSPDNSPTELDESNQRALTQPLLGEQSLLTRCSPGYS-PSDSPLDSPTKYPTLYPPGRIIHLEEESGSGRFGCCSAARYRARWAHEAEFGKILIGPKMLTDHLPNILNQALDKVVADR-TACVSCPGQGGSHAAVA", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q8NCG7-1", "uniprot_id": "DGLB_HUMAN", "id": "Q8NCG7-1", "name": "Diacylglycerol lipase-beta", "aln": "------------------------------------------------------------------MPGMVLFGRRWAIASDDLVFPGFFELVVRVLWWIGILTLYLMHRGKLDCAGGALLSSYLIVLMILLAVVICTVSAIMCVSMRGTICNPGPRKSMSKLLYIRLALFFPEMVWASLGAAWVADG-VQCDRTVVNGIIATVVVSWIIIAATVVSIIIVFDPLGGKMAPYSSAGPSHLDSHDSSQLLNGLKTAATSVWETRIKLLCCCIGKDDHTRVAFSSTAELFSTYFSDTDLVPSDIAAGLALLHQQQDNIRNNQEPAQVVCHAPGSSQEADLDAELENCHHYMQFAAAAYGWPLYIYRNPLTGLCRIGGDCCRSRTTDYDLVGGDQLNCHFGSILHTTGLQYRDFIHVSFHDKVYELPFLVALDHRKESVVVAVRGTMSLQDVLTDLSAESEVLDVECEVQDRLAHKGISQAARYVYQRLINDGILSQAFSIAPEYRLVIVGHSLGGGAAALLATMLRAAYPQVRCYAFSPPRGLWSKALQEYSQSFIVSLVLGKDVIPRLSVTNLEDLKRRILRVVAHCNKPKYKILLHGLWYELFGGNPNNLPTELDGGDQEVLTQPLLGEQSLLTRWSPAYSFSSDSPLDSSPKYPPLYPPGRIIHLQEEGASGRFGCCSAAHYSAKWSHEAEFSKILIGPKMLTDHMPDILMRALDSVVSDR-AACVSCPAQGVSSVDVA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6RA94-1", "uniprot_id": "F6RA94_BOVIN", "id": "F6RA94-1", "name": "Diacylglycerol lipase-beta", "aln": "MKCTCAPGRASTQAQRPSGDRAGLSARAPGPAPACACAESRGGGRVARAPGSGRLRAPRAAGPPSAMPGMVLFGRRWAIASDDLVFPGVFELLLRVLWWVGILMLYLMHRGKLDCPGGVLLSSYLIVLLVLLAIIIGTVSAIVCVSMKGTICNPGPRKSMSKLLYVRLALFLPEMVWASLGAAWIADG-IQCDRTVGNGIIATVVVSWLIIASTVLTILIVFDPLGGKAAPGAPLGPQPLDSRESSQLLSGLRTAATGVWETRVRLLCCCIGRDDHTRVAFSSTAELFSTYFSDTDLVPSDIAAGLALLHQQQDHARSPPEPTEVVTHSPGPFQEADLDAELENCHHYMQFAAAAYGWPLYVYRNPFTGLCRVGGDCCRCRTTDYDLVGGDQLNCHFSSILQTTGLQHRDFIHISFHDKVYELPFLVALDHRKESVVVAIRGTMSLQDILTDLSAESEPLDIECEAQDCWAHKGISQAARYVYRRLVNDGILSQAFSIAPEYRLVVVGHSLGAGAAALLALMLKSPYPQVRCYAFSPPRGLLSKSLYEYSKTFIVSLVLGKDVIPRLSVTNLEDLKRRILRVIAHCNKPKYKILLRGCWYELFGGSPEDLPTELDGGD---LTQPLLGEHSLLVHGSPAYSFSSESPLESPTKYPPLYPPGRIIHLEEEGTSGSCSCSPAARYTVRWAHESEFSRILIGPKMLTDHMPDILMRVLDHVVSDR-AACVSCPAQGGSSVDQA", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "E7FDG8-1", "uniprot_id": "E7FDG8_DANRE", "id": "E7FDG8-1", "name": "Diacylglycerol lipase-beta", "aln": "------------------------------------------------------------------MPGLLVFGRRWRIASDDLVFPGAFELFIRAVWWIVTLVVYTNHKGSFDCKGGAYLQYYLLVLLFLLAVIILTLCAIVYVSAQGTIMNQGPRRSMPLLVYLRAVLYFPEFVWACLGAVWVSDNSSGCQPEEVGAVIGAVVSSWVILLAMAVGVLVVFDPLG---SPGPSRGLRDLQSSESSQLFSSAQSVASRVWENRLRLLCCCLPQDDNHRAAFSSIAQLVSGFFMDTDLVPSDIAAGLALLHQEQDKMEQCRDPDEVLTHSPSSPIREDLEQELEKSAHYMQFAAAAYGWPLYVYSNPLTGVCKLSGDCCGSRHAEYDLVGGDALGCHFTSILQSTGLQYRDFIHISFHNQIYEVPFFVALDHKREAVLVAVRGTLSLKDVLTDLSAECENLSVEGVSGSCYAHKGISQAAHFIYKRLVHDGILSQAFSIAPEYKLVVTGHSLGAGTASLLAVLLHSSQPTLECYAFSPPGGLMSKALADFSKQFVVSVILGKDLVPRLSIPNMEDLKRRLLKMVSNCSKPKYQILLQGCWYEVFGGSPDDSPTELESRREEELSRPLLGAECVSAAPSSSYQSLSSDDSPVQNTHLPLYLPGRVLYVTEDGPSRRP-CFSQVRYRAEWSSEASFRNVMISPKMIKDHMPDVVLRALQSLTQQPFTLCPSSSSNSHLNVI--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:::***** :********* ***.:*.: *: * :* *: :** **. *. **:**:.***::* : *:: ** :*** * ***:**. *:*:* .*::**:***.*** *::.. *: .:: :*: **::: : : ::.****** :* .. *:* .*.:*:.. ::.*. ***.*: ***: :**: *.**** *:*.* :* ************::****:**: :* :*: * *. . :*: *:*:. *** *:... **: : .. . :*: ..: * * :** * * *** ***::****:*****:***:::**:**:*.***::*:*:**:***:*::*:*******.* *.: . *****:***:::::**::*********:****:**:.*****.*:*:*** :*: . * :..****** ** **:* ::*: *:**::** *::****:.*:******:*:::::*.****:***:* ** :***.*:: ****: *::**** . : . *..* ... .: .** ***:::: *:. * * . .:* ..*: *:.* .::*.***: **:*::: :.*: : : : * *...:. . ", "identical_positions": 294, "similar_positions": 220, "identity": "39.73%" }, { "cls_id": "homologset.oma.814414", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5YLM1-1", "uniprot_id": "DGLA_RAT", "id": "Q5YLM1-1", "name": "Diacylglycerol lipase-alpha", "aln": "MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPHEACSLNLVDHGRGYLGILLSCMIAEMAIIWLSMRGGILYTEPRDSMQYVLYVRLAILVIEFIYAIVGIVWLTQYYTSCNDLTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQRNLRTYNLRHRLEEGQATSWSRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDIIAGLVLLRQRQRAKRNAVLDEANNDILAFLSGMPVTRNTKYLDLKNSHEMLRYKEVCYYMLFALAAYGWPMYLMRKPTCGLCQLARSCS-CCLCPARPRFAPGVTIEEDNCCGCNAIAIRRHFLDENMTAVDIVYTSCHDAVYETPFYVAVDHDKKKVVISIRGTLSPKDALTDLTGDAERLPVEGHRGTWLGHKGMVLSAEYIKKKLEQEMVLSQAFGRDLGRGTKHYGLIVVGHSLGAGTAAILSFLLRPQYPTLKCFAYSPPGGLLSEDAMEYSKEFVTAVVLGKDLVPRIGLSQLEGFRRQLLDVLQRSTKPKWRIIVGATKCIPKSELPEDQVEVTALASTRLWTHPSDLTIALSASTPLYPPGRIIHVVHNHPAEQCCCCEQEEPTYFAIWGDNKAFNEVIISPAMLHEHLPYVVMEGLNKVLENYNKGKTALLSAAKVMVSPTEVDLTPELIFQQQPLPTGPPLPTGLALELPATEHRNSSVRSKSQSEMSLEGFSEGRLLSPVAAASAARQDPVELLLLSTQERLAAELQSRRAPLATMESLSDTESLYSFDSRRSSGFRSIRGSPSLHAVLERDEGHLFYIDPAIPEENPSLSSRTELLAADSLSKHSQDTQPLEAALGSGGVTPERPPSAANDEEEAAGGSEGGGVAPRGELALHNGRLGDSPSPQVLEFAEFIDSLFNLDSKSSSFQDLYCMMVPESPTSDYTEGPKSPSQQEILLRAQFEPNLVPKPPRLFAGSAEPSSGISLSPSFPLSSSGELMDLTPTGLSSQECLATDKIRTSTPTGHGASPTKQDDLVISAR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6WQJ1-1", "uniprot_id": "DGLA_MOUSE", "id": "Q6WQJ1-1", "name": "Diacylglycerol lipase-alpha", "aln": "MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPHEACSLNLVDHGRGYLGILLSCMIAEMAIIWLSMRGGILYTEPRDSMQYVLYVRLAILVIEFIYAIVGIVWLTQYYTSCNDLTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQRNLRTYNLRHRLEEGQATSWSRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDIIAGLVLLRQRQRAKRNAVLDEANNDILAFLSGMPVTRNTKYLDLKNSHEMLRYKEVCYYMLFALAAYGWPMYLMRKPTCGLCQLARSCS-CCLCPARPRFAPGVTIEEDNCCGCNAIAIRRHFLDENMTAVDIVYTSCHDAVYETPFYVAVDHDKKKVVISIRGTLSPKDALTDLTGDAERLPVEGHRGTWLGHKGMVLSAEYIKKKLEQEMVLSQAFGRDLGRGTKHYGLIVVGHSLGAGTAAILSFLLRPQYPTLKCFAYSPPGGLLSEDAMEYSKEFVTAVVLGKDLVPRIGLSQLEGFRRQLLDVLQRSTKPKWRIIVGATKCIPKSELPEDQVEVTTLASTRLWTHPSDLTIALSASTPLYPPGRIIHVVHNHPAEQCCCCEQEEPTYFAIWGDNKAFNEVIISPAMLHEHLPYVVMEGLNKVLENYNKGKTALLSAAKVMVSPTEVDLTPELIFQQQPLPTGPPLPTGLALELPATEHRNSSVRSKSQSEMSLEGFSEGRLLSPVAAASAARQDPVELLLLSTQERLAAELQSRRAPLATMESLSDTESLYSFDSRRSSGFRSIRGSPSLHAVLERDEGHLFYIDPAIPEENPSLSSRTELLAADSLSKHSQDTQPLEAALGSGGVTPERPPSATIEEEEAAGGSEGGGVAPRGELALHNGRLGDSPSPQVLEFAEFIDSLFNLDSKSSSFQDLYCMMVPESPTSDYTEGPKSPSQQEILLRAQFEPNLVPKPPRLFAGSAEPSSGISLSPSFPLSSSGELMDLTPTGLSSQECLATDKIRTSTPTGHGASPTKQDDLVISAR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3IFK5-1", "uniprot_id": "G3IFK5_CRIGR", "id": "G3IFK5-1", "name": "Diacylglycerol lipase-alpha", "aln": "MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPHEACSLNLVDHGRGYLGILLSCMIAEMAIIWLSMRGGILYTEPRDSMQYVLYVRLAILVIEFIYAIVGIVWLTQYYTSCNDLTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQRNLRTYNLRHRLEEGQATSWSRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDIIAGLVLLRQRQRAKRNAVLDEANNDILAFLSGMPVTRNTKYLDLKNSHEMLRYKEVCYYMLFALAAYGWPMYLMRKPTCGLCQLARSCS-CCLCPARPRFAPGVTIEEDNCCGCNAIAIRRHFLDENMTAVDIVYTSCHDAVYETPFYVAVDHDKKKVVISIRGTLSPKDALTDLTGDAERLPVEGHRGTWLGHKGMVLSAEYIKKKLEQEMVLSQAFGRDLGRGTKHYGLIVVGHSLGAGTAAILSFLLRPQYPTLKCFAYSPPGGLLSEDAMEYSKEFVTAVVLGKDLVPRIGLSQLEGFRRQLLDVLQRSTKPKWRIIVGATKCIPKSELPEDQVEVTTLASTRLWTHPSDLTIALSASTPLYPPGRIIHVVHNHPAEQCCCCEQEEPTYFAIWGDNKAFNEVIISPAMLHEHLPYVVMEGLNKVLENYNKGKTALLSAAKVMVSPTEVDLTPELIFQQQPLPTGPPLPTGLALELPATDHRNSSVRSKSQSEMSLEGFSEGRLLSPVAAASAARQDPVELLLLSTQERLAAELQSRRAPLATMESLSDTESLYSFDSRRSSGFRSIRGSPSLHAVLERDEGHLFYIDPAIPEENPSLSSRTELLAADSLSKHSQDTQPLEAALGSGGVTPERPPSATNEEEEAAGG-EGGGVAPRGELALHNGRLGDSPSPQVLEFAEFIDSLFNLDSKSSSFQDLYCMVVPESPTSDYAEGPKSPSQQEILLRAQFEPNLVPKPPRIFAGSADPSSGISLSPSFPLSSSGELMDLTPTGLSSQECLATDKIRTSTPTGHGASPTKQDDLVISAR", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "E1BBV2-1", "uniprot_id": "E1BBV2_BOVIN", "id": "E1BBV2-1", "name": "Diacylglycerol lipase-alpha", "aln": "MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPDEACSLNLVDHGRGYLGILLSCMIAEMAIIWLSMRGGILYTEPRESMQYVLYVRLAILVIEFIYAIVGIVWLTQYYTSCNDLTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQRNLRTYNLRHRLEEGQATSWSRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDIIAGLVLLRQRQRAKRNAVLDEANNDILAFLSGMPVTRNTKYLDLKNSHEMLRYKEVCYYMLFALAAYGWPMYLMRKPACGLCQLARSCS-CCLCPARPRFAPGVTIEEDNCCGCNAIAIRRHFLDENMTAVDIVYTSCHDAVYETPFYVAVDHDKKKVVISIRGTLSPKDALTDLTGDAERLPVEGHHGTWLGHKGMVLSAEYIKKKLEQEMVLSQAFGRDLGRGTKHYGLIVVGHSLGAGTAAILSFLLRPQYPTLKCFAYSPPGGLLSEDAMEYSKEFVTAVVLGKDLVPRIGLSQLEGFRRQLLDVLQRSTKPKWRIIVGATKCIPKSELP-EEVEVTTLASTRLWTHPSDLTIALSASTPLYPPGRIIHVVHNHPAEQCCCCEQEEPTYFAIWGDNKAFNEVIISPAMLHEHLPYVVMEGLNKVLENYNKGKTALLSAAKVMVSPTEVDLTPELIFQQQPLPTGPPVPAGLALELPAADHRNSSIRSKSQSEMSLEGFSEGRLLSPVAAASAARQDPVELLLLSTQERLAAELQARRAPLATMESLSDTESLYSFDSRRSSGFRSIRGSPSLHAVLERDEGHLFYIDPAIPEENPSLSSRTELLAADSLSKHSQDTQPLEAALGSGGVTPERPPSAAANEEPEEGGGGA-APRS-GELALQEGRLGDSPSPQVLEFAEFIDSLFNLDSKSSSFQDLYCMVVPESPTSDYAEGPKSPSQQEILLRAQFEPNLVPKPPRLFAGSADPSSGISLSPSFPLSSSGELMDLTPTGLSSQECLAVDKVRTSTPAGRGASPTKQDDLVISAR", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A287AXN8-1", "uniprot_id": "A0A287AXN8_PIG", "id": "A0A287AXN8-1", "name": "Diacylglycerol lipase-alpha", "aln": "MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPNEACSLNLVDHGRGYLGILLSCMIAEMAIIWLSMRGGILYTEPRESMQYVLYVRLAILVIEFIYAIVGIVWLTQYYTSCNDLTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQRNLRTYNLRHRLEEGQATSWSRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDIIAGLVLLRQRQRAKRNAVLDEANNDILAFLSGMPVTRNTKYLDLKNSQEMLRYKEVCYYMLFALAAYGWPMYLMRKPACGLCQLARSCS-CCLCPARPRFAPGVTIEEDNCCGCNAIAIRRHFLDENMTAVDIVYTSCHDAVYETPFYVAVDHDKKKVVISIRGTLSPKDALTDLTGDAERLPVEGHHGTWLGHKGMVLSAEYIKKKLEQEMVLSQAFGRDLGRGTKHYGLIVVGHSLGAGTAAILSFLLRPQYPTLKCFAYSPPGGLLSEDAMEYSKEFVTAVVLGKDLVPRIGLSQLEGFRRQLLDVLQRSTKPKWRIIVGATKCIPKSELP-EEVEVTTLASTRLWTHPSDLTIALSASTPLYPPGRIIHVVHNHPAEQCCCCEQEEPTYFAIWGDNKAFNEVIISPAMLHEHLPYVVMEGLHKVLENYNKGKTALLSAAKVMVSPTEVDLTPELIFQQQPLPTGPPVPAGLALDLPPADHRNSSVRSKSQSEMSLEGFSEGRLLSPVAAASAARQDPVELLLLSTQERLAAELQARRAPLATMESLSDTESLYSFDSRRSSGFRSIRGSPSLHAVLERDEGHLFYIDPAIPEENPSLSSRTELLAADSLSKHSQDTQPLEAALGSGGVTPERPPSAAAHEEPEEEGGGP-APRS-AELALHDGRLGDSPSPQVLEFAEFIDSLFNLDSKSSSFQDLYCMVVPESPTSDYAEGPKSPSQQEILLRAQFEPNLVPKPPRLFAGSADPSSGISLSPSFPLSSSGELMDLTPTGLSSQECLAVDKIRTSTPTGHGASPP-QDDLVISAR", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q9Y4D2-1", "uniprot_id": "DGLA_HUMAN", "id": "Q9Y4D2-1", "name": "Diacylglycerol lipase-alpha", "aln": "MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPHEACSLNLVDHGRGYLGILLSCMIAEMAIIWLSMRGGILYTEPRDSMQYVLYVRLAILVIEFIYAIVGIVWLTQYYTSCNDLTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQRNLRTYNLRHRLEEGQATSWSRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDIIAGLVLLRQRQRAKRNAVLDEANNDILAFLSGMPVTRNTKYLDLKNSQEMLRYKEVCYYMLFALAAYGWPMYLMRKPACGLCQLARSCS-CCLCPARPRFAPGVTIEEDNCCGCNAIAIRRHFLDENMTAVDIVYTSCHDAVYETPFYVAVDHDKKKVVISIRGTLSPKDALTDLTGDAERLPVEGHHGTWLGHKGMVLSAEYIKKKLEQEMVLSQAFGRDLGRGTKHYGLIVVGHSLGAGTAAILSFLLRPQYPTLKCFAYSPPGGLLSEDAMEYSKEFVTAVVLGKDLVPRIGLSQLEGFRRQLLDVLQRSTKPKWRIIVGATKCIPKSELP-EEVEVTTLASTRLWTHPSDLTIALSASTPLYPPGRIIHVVHNHPAEQCCCCEQEEPTYFAIWGDNKAFNEVIISPAMLHEHLPYVVMEGLNKVLENYNKGKTALLSAAKVMVSPTEVDLTPELIFQQQPLPTGPPMPTGLALELPTADHRNSSVRSKSQSEMSLEGFSEGRLLSPVVAA-AARQDPVELLLLSTQERLAAELQARRAPLATMESLSDTESLYSFDSRRSSGFRSIRGSPSLHAVLERDEGHLFYIDPAIPEENPSLSSRTELLAADSLSKHSQDTQPLEAALGSGGVTPERPPSAAANDEEEEVGGGGGGPASRGELALHNGRLGDSPSPQVLEFAEFIDSLFNLDSKSSSFQDLYCMVVPESPTSDYAEGPKSPSQQEILLRAQFEPNLVPKPPRLFAGSADPSSGISLSPSFPLSSSGELMDLTPTGLSSQECLAADKIRTSTPTGHGASPAKQDELVISAR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0ZB80-1", "uniprot_id": "A0A8V0ZB80_CHICK", "id": "A0A8V0ZB80-1", "name": "Diacylglycerol lipase-alpha", "aln": "MPGIVVFRRRWSVGSDDLVLPAVFLFLLHTTWFVILSVVLFGLVYNPNETCSLNLVDHGRGYLGILLSCMIAEMAIIWLSMRGSILYTEPRDSMQYVLYVRLAILVIEFVYAIVGIIWLTQYYTSCNDITAKSVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQRNLRTYNLRHRLEEGQASSWTRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDIIAGLVLLRQRQRAKRNAVLDEANNDILAFLSGMPVTRNTKYLDLKNAQEMQRYKEVCYYMLFALAAYGWPIYLMRKPTCGLCHLARSCSCCCLCPSRPRYAPSVTIEEDNCCGCNAIAIRRHFLDENMTSVDIVYTSCHDAVYETPFYVAVDHEKKKVVISIRGTLSPKDALTDLTGDAERLPVEGHHGTWLGHKGMVLSAEYIKKKLEQEMVLSQAFGRDLGRGTKHYGLIVVGHSLGAGTAAILSFLLRPQYPSLKCFAYSPPGGLLSEDAMEYSKEFVTAVVLGKDLVPRIGLSQLEGFRRQLLDVLQRSNKPKWRIIVGATKCIPKSELP-EETEENSVTSNRLWTHPSDLTIALSASTPLYPPGRIIHVVHNHPAEQCCCCEQEDPTYFAIWGDNKAFNEVIISPAMLHEHLPYVVMEGLNKVLENYNKGKTALLSAAKVMVSPTEVDLTPELIFQSQPLPSGPSVQIGTG--ALTADRRNSSTKSKSHSEISLEGFYETKPLSP------VQKDPVELLLLDTKERLSVELQDRRAPLATMESLSDNESIYSFDSRRSSGFRSIRGSPSLHAVMEKDETHCFYIDPAIPEENPSLSSRTELLAADSLSKHSQETQAPDNALNSGGTTPQR----RCSEEGASSEGDRVSLAPREELALQNGRLADVPSPQVLEFAEFIDSLFNLDSKSSSFQDIYCMMVSDS-SSDFAEMPKSVSDQEILLRAQYEPNLVPKPPRLFAGSTDPSSGISVSPSFPLSSSGELMDITPTGVSSQECLATDKIRTSTPTGHVTSPAKQEDLMISAL", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********************:************************.*:*********************************.*******:*****************:******:***********:***.**********************************************************:**:***************************************************************************************::** *******************:******:****:****** *****:***:**.**************************:***********************:*********************************:*******************************************************************:*********************************************************.******************** ::.* .:::*.*******************************************:***********************************:***********************************.****:**.: * . .:::**** :***:**:***** * : *** .::********.*:***:.*** *************.**:***********************:*:** * *******************************:**. : **.***.**:* :* . . ****::***.* ***************************:***:*.:* :**::* *** *:********:**********:****::******:**************:****:*******.**:*****:*: :**. *::*:*** ", "identical_positions": 898, "similar_positions": 94, "identity": "85.93%" }, { "cls_id": "homologset.oma.814482", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C0E2-1", "uniprot_id": "VP26B_MOUSE", "id": "Q8C0E2-1", "name": "Vacuolar protein sorting-associated protein 26B", "aln": "MSFFG--FGQSVEVEILLNDAESRKRAEHKTE------DGKKEKYFLFYDGETVSGKVSLSLKNPNKRLEHQGIKIEFIGQIELYYDRGN---------------------------HHEFVSLVKDLARPGEITQSQAFDFEFTHVEKPYESYTGQNVKLRYFLRATISRRLN-DVVKEMDIVVHTLSTY-------------------------------------------------PELNSS-----IKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMEIDIIKRETTGTGPNVYHENDTIAKYEIMDGAPVRGESIPIRLFLAGYELTPTMRDINKKFSVRYYLNLVLIDEEERRYFKQQEVVLWRKGDIVR-----------KSMSHQAAIASQRFEGTTSLGEVRTPGQLSDNNSRQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B1WBS4-1", "uniprot_id": "B1WBS4_RAT", "id": "B1WBS4-1", "name": "", "aln": "MSFFG--FGQSVEVEILLNDAESRKRAEHKTE------DGKKEKYFLFYDGETVSGKVSLSLKNPNKRLEHQGIKIEFIGQIELYYDRGN---------------------------HHEFVSLVKDLARPGEITQSQAFDFEFTHVEKPYESYTGQNVKLRYFLRATISRRLN-DVVKEMDIVVHTLSTY-------------------------------------------------PELNSS-----IKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMEIDIIKRETTGTGPNVYHENDTIAKYEIMDGAPVRGESIPIRLFLAGYELTPTMRDINKKFSVRYYLNLVLIDEEERRYFKQQEVVLWRKGDIVR-----------KSMSHQAAIASQRFEGTTSLGEVRTPGQLSDNNSRQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3GTV9-1", "uniprot_id": "G3GTV9_CRIGR", "id": "G3GTV9-1", "name": "", "aln": "MSFFG--FGQSVEVEILLNDAESRKRAEHKTE------DGKKEKYFLFYDGETVSGKVSLSLKNPNKRLEHQGIKIEFIGQIELYYDRGN---------------------------HHEFVSLVKDLARPGEITQSQAFDFEFTHVEKPYESYTGQNVKLRYFLRATISRRLN-DVVKEMDIVVHTLSTY-------------------------------------------------PELNSS-----IKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMEIDIIKRETTGTGPNVYHENDTIAKYEIMDGAPVRGESIPIRLFLAGYELTPTMRDINKKFSVRYYLNLVLIDEEERRYFKQQEVVLWRKGDIVR-----------KSMSHQAAIASQRFEGTTSLGEVRTPGPLSDNNSRQ", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q4G0F5-1", "uniprot_id": "VP26B_HUMAN", "id": "Q4G0F5-1", "name": "Vacuolar protein sorting-associated protein 26B", "aln": "MSFFG--FGQSVEVEILLNDAESRKRAEHKTE------DGKKEKYFLFYDGETVSGKVSLALKNPNKRLEHQGIKIEFIGQIELYYDRGN---------------------------HHEFVSLVKDLARPGEITQSQAFDFEFTHVEKPYESYTGQNVKLRYFLRATISRRLN-DVVKEMDIVVHTLSTY-------------------------------------------------PELNSS-----IKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMEIDIIKRETTGTGPNVYHENDTIAKYEIMDGAPVRGESIPIRLFLAGYELTPTMRDINKKFSVRYYLNLVLIDEEERRYFKQQEVVLWRKGDIVR-----------KSMSHQAAIASQRFEGTTSLGEVRTPSQLSDNNCRQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1BMM4-1", "uniprot_id": "E1BMM4_BOVIN", "id": "E1BMM4-1", "name": "", "aln": "MSFFG--FGQSVDVDILLNDADSRRRAEHKTE------DGKKDKYFLFYDGETVSGKVSLALKNPNKRLEHQGIKVEFIGQIELYYDRGN---------------------------HHEFVSLVKDLARPGEVTQSQAFDFEFTHVEKPYESYTGQNVKLRYFLRATISRRLN-DVVKEMDIVVHTLSTY-------------------------------------------------PELNSS-----IKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMEIDIIKRETTGTGPNVYHENDTIAKYEIMDGAPVRGESIPIRLFLAGYELTPTMRDINKKFSVRYYLNLVLIDDEERRYFKQQEVVLWRKGDIVR-----------KSMSHQAAIASQRFEGTTPLGEARTPGPLSDSGNRQ", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1NPH4-1", "uniprot_id": "F1NPH4_CHICK", "id": "F1NPH4-1", "name": "", "aln": "MSFFG--FGQSAEVELVLSDAESRRRVEHKTE------EGKKEKYFLFYDGETVSGRVILTLKHPNRRLEHQGIKVEFIGQIELYYDRGN---------------------------HHEFVSLVKDLARPGEFTQSQIFDFEFTHVEKPYESYTGQNVKLRYFLRATVSRRLN-DVVKEMDIVVHTLSTY-------------------------------------------------PELNSS-----IKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMEIDIIKRETTGTGPNVYHENDTIAKYEIMDGAPVRGESIPIRLFLAGYELTPTMRDINKKFSVRYYLNLVLIDEEERRYFKQQEVVLWRKGDIVR-----------KSMSHQAAIASQRFEGTSSHTEAKTPSQPAENNGRQ", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q55CA0-1", "uniprot_id": "VPS26_DICDI", "id": "Q55CA0-1", "name": "Vacuolar protein sorting-associated protein 26", "aln": "MNFFSNNFGTPCNVEFELDNCQNRKTIEVTQD------KGKTEKLFVFIGNEPVSGKVSINIKEKTKKIEHTGIRVEFVGQIELFYDRGN---------------------------HYEFTSLVRELAPAGELTENKTFSYDFSNVEKQYESYNGTNVRLRYFVRLTIGRSFASNIVKEYDIWVINFVKP-------------------------------------------------PESNSN-----IKMEVGIEDCLHIEFEYNKSKYHLKDVIIGKIYFLLVRIKIKYMEIALIKRESTGSGPNVFNESETLTKFEIMDGAPVRGESIPVRLFLSVFDLTPTYRSVHNKFSVKYFLNLALVDEDDKKYFKQQEITLWRRGVTKPGLPGSTNNNNNNNTSNTNNTNTPQQKVTESQNEVPEPENNSSDESD-", "tax_id": 44689, "tax_name": "Social amoeba" }, { "uniprot_ac": "P40335-1", "uniprot_id": "PEP8_YEAST", "id": "P40335-1", "name": "Carboxypeptidase Y-deficient protein 8", "aln": "MSIFF---KPPIDIEILFDNEESRKHVDIATRSSNSSYKSMKESLPVYEDGESLGGIVTLRVRD-SKKVDHLGIKVSVIGSIDMLKSHGSGNSSSKKVTSSTSSSSSNGSVDVRKNSVDQFLCQSYDLCPAGELQHSQSFPFLFRDLSKRYESYKGKNVDVAYYVKVTVMRKST-DISKIKRFWVYLYNSVTTAPNTLSANETKATTNDIAGGNYAADNASDNTQTKSTQGEAADVNQVLPISHSNNEPKPVRLDIGIENCLHIEFEYAKSQYSLKEVIVGRIYFLLTRLRIKHMELSLITRESSGLQTSNVMTDSTAIRYEIMDGSSVKGETIPIRLFLSGYDLTPNMS--CNYFNVKNYLSLVIIDEDGRRYFKQSEITLYRTR---------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:* . :::: :.: :.*: : .. .:. :: ..*.:.* * : ::. .::::* **::..:*.*:: .:*. :* . :*. .**. ..: * : * .:.* ****.* ** : *::: *: * :: * : * . * :*. :::::***:******** **:* **:**:*:*****.*::**:**: :*.**::* .. ..* ::*****:.*:**:**:****: ::***. : *.*: :*.*.::*:: ::****.*:.*:* ", "identical_positions": 96, "similar_positions": 121, "identity": "21.97%" }, { "cls_id": "homologset.oma.814483", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P40336-1", "uniprot_id": "VP26A_MOUSE", "id": "P40336-1", "name": "Vacuolar protein sorting-associated protein 26A", "aln": "MSFLGGFFGPICEIDVALNDGETRKMAEMKTEDGKVEKHYLFYDGESVSGKVNLAFKQPGKRLEHQGIRIEFVGQIELFNDKSNTHEFVNLVKELALPGELTQSRSYDFEFMQVEKPYESYIGANVRLRYFLKVTIVRRLTDLVKEY-DLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEITGIGPSTTTETETIAKYEIMDGAPVKGESIPIRLFLAGYDPTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIILWRKAPEKLRKQRTNFHQRFESPDSQ--ASAEQPEM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AY86-1", "uniprot_id": "VP26A_RAT", "id": "Q6AY86-1", "name": "Vacuolar protein sorting-associated protein 26A", "aln": "MSFLGGFFGPICEIDVALSDGETRKMAEMKTEDGKVEKHYLFYDGESVSGKVNLAFKQPGKRLEHQGIRIEFVGQIELFNDKSNTHEFVNLVKELALPGELTQSRSYDFEFMQVEKPYESYIGANVRLRYFLKVTIVRRLTDLVKEY-DLIVHQLATYPEVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEITGIGPSTTTETETIAKYEIMDGAPVKGESIPIRLFLAGYDPTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIILWRKAPEKLRKQRTNFHQRFESPESQ--ASAEQPEM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A5G2R839-1", "uniprot_id": "A0A5G2R839_PIG", "id": "A0A5G2R839-1", "name": "", "aln": "-SFLGGFFGPICEIDVVLNDGETRKMAEMKTEDGKVEKHYLFYDGESVSGKVNLAFKQPGKRLEHQGIRIEFVGQIELFNDKSNTHEFVNLVKELALPGELTQSRSYDFEFMQVEKPYESYIGANVRLRYFLKVTIVRRLTDLVKEY-DLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEITGIGPSTTTETETIAKYEIMDGAPVKGESIPIRLFLAGYDPTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIILWRKAPEKLRKQRTNFHQRFESPESQ--ASAEQPEM", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q0VD53-1", "uniprot_id": "VP26A_BOVIN", "id": "Q0VD53-1", "name": "Vacuolar protein sorting-associated protein 26A", "aln": "MSFLGGFFGPICEIDVVLNDGETRKMAEMKTEDGKVEKHYLFYDGESVSGKVNLAFKQPGKRLEHQGIRIEFVGQIELFNDKSNTHEFVNLVKELALPGELTQSRSYDFEFMQVEKPYESYIGANVRLRYFLKVTIVRRLTDLVKEY-DLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEITGIGPSTTTETETIAKYEIMDGAPVKGESIPIRLFLAGYDPTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIILWRKAPEKLRKQRTNFHQRFESPESQ--ASAEQPEM", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "O75436-1", "uniprot_id": "VP26A_HUMAN", "id": "O75436-1", "name": "Vacuolar protein sorting-associated protein 26A", "aln": "MSFLGGFFGPICEIDIVLNDGETRKMAEMKTEDGKVEKHYLFYDGESVSGKVNLAFKQPGKRLEHQGIRIEFVGQIELFNDKSNTHEFVNLVKELALPGELTQSRSYDFEFMQVEKPYESYIGANVRLRYFLKVTIVRRLTDLVKEY-DLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEITGIGPSTTTETETIAKYEIMDGAPVKGESIPIRLFLAGYDPTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIILWRKAPEKLRKQRTNFHQRFESPESQ--ASAEQPEM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3H6T8-1", "uniprot_id": "G3H6T8_CRIGR", "id": "G3H6T8-1", "name": "", "aln": "MSFLGGFFGPICEIDVALNDGESRKMAEMKTEDGKVEKHYLFYDGESVSGKVNLAFKQPGKRLEHQGIRIEFVGQIELFNDKSNTHEFVNLVKELALPGELTQSRSYDFEFMQVEKPYESYIGANVRLRYFLKVTIVRRLTDLVKEY-DLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEITGIGPSTTTETETIAKYEIMDGAPVKGESIPIRLFLAGYDPTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIILWRKAPEKLRKQRTNFHQRFESPESQ--ASAEQPEM", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q6TNP8-1", "uniprot_id": "VP26A_DANRE", "id": "Q6TNP8-1", "name": "Vacuolar protein sorting-associated protein 26A", "aln": "MSFLGGLFGPVCEIDVILNDAESRKTAELKTEEGKLEKHYLFYDGESVSGKVNINVKQTSKRLEHQGIRIEFVGQIELFSDKSNTHEFVNLVKELALPGELTQNRSYDFEFMQVEKPYESYVGANVRLRYFLKVTIVRRLSDLVKEY-DLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEMTGIGPSTTTETETVAKYEIMDGAPVKGESIPIRLFLAGYDLTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIVLWRKAPEKMRKR--NFHQRYESPEPRPSLSAEQPEM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9FJD0-1", "uniprot_id": "VP26A_ARATH", "id": "Q9FJD0-1", "name": "Vacuolar protein sorting-associated protein 26A", "aln": "MNYLLGAFKPACNISITFTDGKNRKQVPTKKDNGQIVMNPLFQSQETIAGKINIEPYQ-GKKVEHNGVKVELLGQIEMYFDRGNFYDFTSLVREIDVPGEIYERKTYPFEFSSVEMPYETYNGVNVRLRYVLKVTVTRGYAGSIVEYQDFVVRNYVPLPPINNSIKMEVGIEDCLHIEFEYNKSKYHLKDVILGKIYFLLVRIKIKNMDLEIRRRESTGAGANTHVETETLAKFELMDGAPVRGESIPVRVFLTPYDLTPTHKNINNKFSVKYYLNLVLVDEEDRRYFKQQEITLYRLKEETS---------------------------", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:* * * * *:*.: :.*.:.** . *.::*:: : ** . *:::**:*: * .*::**:*:::*::****:: *:.* ::*..**:*: :***: : ::* *** .** ***:* *.******.****:.* :. : ** *::*:: .. * :*******************************:************::*:*:: ::* ** *..* .****:**:*:******:*****:*:**: ** *** :::*:****:*:******************* *:* *. ", "identical_positions": 167, "similar_positions": 89, "identity": "50.61%" }, { "cls_id": "homologset.oma.814506", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q4QQT4-1", "uniprot_id": "2AAB_RAT", "id": "Q4QQT4-1", "name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "aln": "--------------MAGAAGPGTVPGAAGGDGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFLTDTIY-DEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLESLATVEETVVRDKAVESLRQISQEHTPVALEAHFVPLVKRLASGDWFTSRTSACGLFSVCYPRAS-NAVKAEIRQHFRSLCSDDTPMVRRAAASKLGEFAKVLEL------DSVKTEIVPLFTNLASDEQDSVRLLAVEACVSIAQLLSQ---DDLEALVMPTLRQAAEDKSWRVRYMVADKFSELQKAVGP-KIALSDLIPAFQSLLRDCEAEVRAAAAHKVRELCENLPTEGRETVIMNQILPYIKELVSDTNQHVKSALASVIMGLSTVLGKENTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTIVPKVLVMAND--PNYLHRMTTLFCINALSEACGKEITTKQMLPIVLKMAGDQVANVRFNVAKSLQKIGPILDT------NALQGEVKPVLQKLGQDEDMDVKYFAQEAISVLALA---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A9J7FV46-1", "uniprot_id": "A0A9J7FV46_CRIGR", "id": "A0A9J7FV46-1", "name": "", "aln": "--------------MAGAAGPGAGPGAAGGDGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFLTDTIY-DEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLESLATVEETVVRDKAVESLRQISQEHTPVALEAHFVPLVKRLASGDWFTSRTSACGLFSVCYPRAS-NAVKAEIRQHFRSLCSDDTPMVRRAAASKLGEFAKVLEL------DSVKTEIVPLFTNLASDEQDSVRLLAVEACVSIAQLLSQ---DDLEALVMPTLRQAAEDKSWRVRYMVADKFSELQKAVGP-KITLNDLIPAFQSLLKDCEAEVRAAAAHKVKELCENLPTEGRETIIMTQILPYIKELVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTIVPRVLVMAND--PNYLHRMTTLFCINALSEACGKEITTKQMLPIVLKMAGDQVANVRFNVAKSLQKIGPILDT------NALQGEVKPVLQKLGQDEDMDVKYFAQEAISVVAQRLRKLDFPVKDSEEPSIPGVDKNLFLRPRVPGENTGKFLPLMSRHREAERLQWLPRRQ", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "P30154-1", "uniprot_id": "2AAB_HUMAN", "id": "P30154-1", "name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "aln": "--------------MAGASELGTGPGAAGGDGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIY-DEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLENLATVEETVVRDKAVESLRQISQEHTPVALEAYFVPLVKRLASGDWFTSRTSACGLFSVCYPRAS-NAVKAEIRQQFRSLCSDDTPMVRRAAASKLGEFAKVLEL------DSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQ---DDLETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGP-KITLNDLIPAFQNLLKDCEAEVRAAAAHKVKELGENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPLFLAQLKDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTIVPKVLVMAND--PNYLHRMTTLFCINALSEACGQEITTKQMLPIVLKMAGDQVANVRFNVAKSLQKIGPILDT------NALQGEVKPVLQKLGQDEDMDVKYFAQEAISVLALA---------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PMV7-1", "uniprot_id": "A5PMV7_DANRE", "id": "A5PMV7-1", "name": "", "aln": "--------------------------MAGADSDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFLTDTIY-DEDEVLLALAEQLGNFTMLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRKISHEHSPVDLEVHFEPLVKRLASGDWFTSRTSACGLFSVCYPRVS-STVKAEIRQHFRTLCSDDTPMVRRAAASKLGEFAKVLEL------EYVKSDIISLFTALASDEQDSVRLLAVEAGVSIATLLPQ---EDLEALVMPTLRQAAEDKSWRVRYMVADKFSDLQKAVGP-EITKNDLVPAFQNLLKDCEAEVRAAAANKVKEFCENLPEDSRETIIMTHILPCVKELVSDTNQHVKSALASVIMGLSTILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATCNLMKLVEKFGAEWAQNTIVPKVLGMAND--PNYLHRMTTLFCINALSEVCGQEITTKHMLPVVLKMSNDQVANVRFNVAKSLQKIGPVLDS------SCLQTEVKPVLEKLASDQDMDVKYFAQEAISVLSLA---------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q54QR9-1", "uniprot_id": "2AAA_DICDI", "id": "Q54QR9-1", "name": "Protein phosphatase 2A scaffold subunit", "aln": "-------------------------MASINTESDDYHPIVILIDELKNEDIQLRLNSIKKLQSIAKALGPERTRTELIPYLQDSVLEDEDEVLVVLSEELGNLIEFVGGAEHAVCLLPPLQILAGAEELVVREKAVESLCKIAKEIPTSSFEESFLPLLFSLSKADWFTSRTSACGLFTVSYPRAN-AEMKKSLRKTFGGLCHDDTPMVKRAAATNLGSFAKQIEK------ESVKSEILPLFQSLSTDEQDSVRLLGVENCALLGSMLTN---EENIQFILPTIKASSLDKSWRVRYMVARLLKELCESMGT-EITKTELIGAFVKLLKDTEAEVRTEASLRIADVCSLLTKEMN----IKTILPCVKDLVSDSSQHVRAALAQVIMSLAPIYGKEDTLTHLLELFLHLLKDDFPDVRLNIISKLDQVSKVIGIEMLSQSLLPAIVELAEDHQWRVRLAIIDYIPLLASQLGVEFFDEKLGNLCMTWLGDPVFSIREAATNNLKKLTEVFGVDWAKNNIIPKVLSLHSH--PNYLYRMTTLFSISTLSTVVGGDVISSSMVPLLAKMVSDKVPNIRFNVAKTFQTIIPLLDS------TIVQSRVKPLLVKLHEDTDKDVKFYASQALQLC------------------------------------------------------------", "tax_id": 44689, "tax_name": "Social amoeba" }, { "uniprot_ac": "Q38950-1", "uniprot_id": "2AAB_ARATH", "id": "Q38950-1", "name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "aln": "----------------------------MSMIDEPLYPIAVLIDELKNDDIQLRLNSIRRLSTIARALGEERTRKELIPFLSENND-DDDEVLLAMAEELGVFIPYVGGVEYAHVLLPPLETLSTVEETCVREKAVESLCRVGSQMRESDLVDHFISLVKRLAAGEWFTARVSACGVFHIAYPSAP-DMLKTELRSLYTQLCQDDMPMVRRAAATNLGKFAATVES------AHLKTDVMSMFEDLTQDDQDSVRLLAVEGCAALGKLLEP---QDCVQHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGP-EPTRTELVPAYVRLLRDNEAEVRIAAAGKVTKFCRILNPEIA----IQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEHLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDDKLGALCMQWLQDKVHSIRDAAANNLKRLAEEFGPEWAMQHIVPQVLEMVNN--PHYLYRMTILRAVSLLAPVMGSEITCSKLLPVVMTASKDRVPNIKFNVAKVLQSLIPIVDQ------SVVEKTIRPGLVELSEDPDVDVRFFANQALQSIDNVMMSS-----------------------------------------------------", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "P31383-1", "uniprot_id": "2AAA_YEAST", "id": "P31383-1", "name": "Protein phosphatase PP2A regulatory subunit A", "aln": "MSGARSTTAGAVPSAATTSTTSTTSNSKDSDSNESLYPLALLMDELKHDDIANRVEAMKKLDTIALALGPERTRNELIPFLTEVAQDDEDEVFAVLAEQLGKFVPYIGGPQYATILLPVLEILASAEETLVREKAVDSLNNVAQELSQEQLFSDFVPLIEHLATADWFSSKVSACGLFKSVIVRIKDDSLRKNILALYLQLAQDDTPMVKRAVGKNLPILIDLLTQNLGLSTDEDWDYISNIFQKIINDNQDSVKFLAVDCLISILKFFNAKGDESHTQDLLNSAVKLIGDEAWRVRYMAADRFSDLASQFSSNQAYIDELVQPFLNLCEDNEGDVREAVAKQVSGFAKFLN---DPSIILNKILPAVQNLSMDESETVRSALASKITNIVLLLNKDQVINNFLPILLNMLRDEFPDVRLNIIASLKVVNDVIGIELLSDSLLPAITELAKDVNWRVRMAIIEYIPILAEQLGMQFFDQQLSDLCLSWLWDTVYSIREAAVNNLKRLTEIFGSDWCRDEIISRLLKFDLQLLENFVSRFTILSALTTLVPVVSLDVVTEQLLPFISHLADDGVPNIRFNVAKSYAVIVKVLIKDEAKYDALIKNTILPSLQTLCQDEDVDVKYFAKKSLAECQELLKN------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :*:.:*:***:::*: *::::::*.:** *** ****.**:*:* : *:***: .::*:** : :** :.. *** *: *: .** **:***:** .:. : : * .*: *: .:**:::.****:* :: .: : *. ** ***:**...:* : : : :* : *:****::*.*: : :: :. :: *::******.* : :* . ... : :*: .: * .* *.:** .: :: . * : *** :::* * .: *::***. * .: : .*: .: ::* ::* *:*: *:******:.*. *..**** **:******.***:* :****:***:*:*:** ***: ***::*. **: ** * *.:**:**. ** :*.: ** :*. : *:.::* : . ::: *:* * .:. * . . :: . ::*.: * *.*::***** : :: :: : * * * .* * **:::*.::: ", "identical_positions": 184, "similar_positions": 194, "identity": "26.59%" }, { "cls_id": "homologset.oma.814507", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI34-1", "uniprot_id": "Q5XI34_RAT", "id": "Q5XI34-1", "name": "", "aln": "MAAADGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMTQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEALTVLSLA----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54612-1", "uniprot_id": "2AAA_PIG", "id": "P54612-1", "name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "aln": "MAAADGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMTQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEALTVLSLA----", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q76MZ3-1", "uniprot_id": "2AAA_MOUSE", "id": "Q76MZ3-1", "name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "aln": "MAAADGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMTQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEALTVLSLA----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30153-1", "uniprot_id": "2AAA_HUMAN", "id": "P30153-1", "name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "aln": "MAAADGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEALTVLSLA----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q38951-1", "uniprot_id": "2AAG_ARATH", "id": "Q38951-1", "name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A gamma isoform", "aln": "MSMVD--EPLYPIAVLIDELKNDDIQRRLNSIKRLSIIARALGEERTRKELIPFLSENNDDDDEVLLAMAEELGGFILYVGGVEYAYVLLPPLETLSTVEETCVREKAVDSLCRIGAQMRESDLVEHFTPLAKRLSAGEWFTARVSACGIFHIAYPSAPDVLKTELRSIYGQLCQDDMPMVRRAAATNLGKFAATIESAHLKTDIMSMFEDLTQDDQDSVRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRTDLVPAYARLLCDNEAEVRIAAAGKVTKFCRILNP----ELAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEHLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDEKLGALCMQWLQDKVHSIREAAANNLKRLAEEFGPEWAMQHIVPQVLEMINNPHYLYRMTILRAVSLLAPVMGSEITCSKLLPAVITASKDRVPNIKFNVAKMMQSLIPIVDQAVVENMIRPCLVELSEDPDVDVRYFANQALQSIDNVMMSS", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .* :.***********:*:*:* ******:** ** *** ****.**:***::. *:******:**:** * *** **.: ******:*:***** **:***:** *. : *** **.**.***:.*:***:*.****:* :.** ....:*:***. : :**.** ********::**:** .:* ::*::*:.**.:*:.*:**********.*. :.:** :* * ::*.: : ::***********::: ** :***** *:******: .*: * ***** **: **.:**. *.. :: : :****:*** **:.***:*********::*:**** *******:**: **** *:*******:** **:**** *************** :**********:****.**** ******.:*** ** *:*::*****:.***:*.*:** *** *:*:** * .:*:**:*** * .:.:*: * *.:** .::**:*: : * *.*::***** :*.: **:*::.::. ::* * :*::* ****:***::** :. . ", "identical_positions": 340, "similar_positions": 159, "identity": "57.34%" }, { "cls_id": "homologset.oma.814541", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NVZ3-1", "uniprot_id": "NECP2_HUMAN", "id": "Q9NVZ3-1", "name": "Adaptin ear-binding coat-associated protein 2", "aln": "------MEESGYESVLCVKPDVHVYRIPPRATNRGYRAAEWQLDQPSWSGRLRITAKGQMAYIKLEDRTSGELFAQAPVDQFPG-TAVESVTDSSRYFVIRIEDGNGRRAFIGIGFGDRGDAFDFNVALQDHFKWVKQQCE-----FAKQAQNPDQGPKLDLGFKEGQTIKLNIANMKKKEGAAGNPRVRPASTGG---LSLLPPP-PGGKTSTLIPPPGEQLAVGGSLVQPAVAPSS--GGAPVPWPQPNP----ATADIWGDFTKSTGSTSSQTQ-PGTGWVQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1SUS2-1", "uniprot_id": "F1SUS2_PIG", "id": "F1SUS2-1", "name": "", "aln": "------MEEGGYESVLCVKPEVHVYRIPPRATNRGYRASEWQLDQPSWSGRLRITAKGQVAYIKLEDRTSGELFAQAPVDQFPG-TAVESVTDSSRYFVIRIEDGNGRRAFIGIGFGDRGDAFDFNVALQDHFKWVKQQCE-----FAKQAQNPDQGPKLDLSFKEGQTIKLNIANMKKKEGAAGTPRARPASTGG---LSLLPPP-PGGRTSTLTAHPGEHLSVGGSVIQPAVVPSS--GGATVSWPQPKPA-TAATADIWGDFTKSTGSTSSQPQ-PGTGWVQF", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q9D1J1-1", "uniprot_id": "NECP2_MOUSE", "id": "Q9D1J1-1", "name": "Adaptin ear-binding coat-associated protein 2", "aln": "------MEESEYESVLCVKPEVHVYRIPPRATNRGYRASEWQLDQPSWSGRLRITAKGKVAYIKLEDRTSGELFAQAPVDQFPG-TAVESVTDSSRYFVIRIEDGNGRRAFIGLGFGDRGDAFDFNVALQDHFKWVKQQCE-----FAKQAQNPDEGPKLDLGFKDGQTIKINIANMRKKEGAAGTPRARPTSAGG---LSLLPPP-PGGKSSTVIPPSGEQLSVGGSLVQPAVVSGS--GGATELWPQSKPA-AAATADIWGDFTKSTGSPSSQSQ-PGTGWVQF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1L1S0X6-1", "uniprot_id": "A0A1L1S0X6_CHICK", "id": "A0A1L1S0X6-1", "name": "", "aln": "------MEED-YEAVLCVKPAVHVYRVPPRASNRGYRAAEWQLDQPAWSGRLRITAKGKTAFIKLEDKTSGELFAQAPVEQFPG-IAVESVTDSSRYFVLRIEDGNGRRAFIGVGFVDRGDAFDFNVALQDHFKWVRQQNE-----LAKQSENPDQAPKLDLGFKEGQTIKLNIANMKKKEGATGNTRPRPAGPGG---LSLLPPP-PGGKSSMPTLPSGEQLPS--SLSTPTRLPGTPITDSLLSWPQPTAAPSAPTTDVWGDFTKASGSDSNQTQ-ANAGWVQF", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9VXB0-1", "uniprot_id": "NECAP_DROME", "id": "Q9VXB0-1", "name": "NECAP-like protein CG9132", "aln": "---------MEYESVLIVKPEVFIYKIPPRASNRGYRAGDWNLKEPTWTGRMRLVAKGTAVVLKLEDKTSGALFANCPIDTYPG-VAIEAVSDSSRYFVIRVQDDNGRSAFLGLGFGDRSDSFDLNVALQDHFKWVKNQEQ-----IEKEKTEPKQ--ELDLGFKEGETIKINMR-ITKKDGSEGSSRTG-KNKGS---SGVLPPP-PGGLGKIAPPPAA-------AAANTTVRQSP--GVSPAHRP-------AAGGSEWTDYASAGGNQGQQNS-ANANWVQF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q681Q7-1", "uniprot_id": "Y1390_ARATH", "id": "Q681Q7-1", "name": "Uncharacterized protein At1g03900", "aln": "MSFEEEEEEETFEHTLLVVREVSVYKIPPRTTSGGYKCGEWLQSDKIWSGRLRVVSCKDRCEIRLEDSNSGDLFAACFVDPGRRENSVEPSLDSSRYFVLRIDDGRGKYAFIGLGFAERNEAFDFNVALSDHEKYVRREKEKETGETSESDNHIDIHPAVNHRLKEGETIRINVKPKPTTNG-TGMLSAALSGTGKPKPLALAPPPKAAGVTRSPLPPPP-------NDPVASRIASDGCKESRRNEP------LSDLSQLKKNLPSTAGSGSSKSTGAASGWAAF", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .* * * :*::***::. **:..:* .: *:**:*:.: ::*** .** *** . :: ::*. *******:*::*..*: **:*:** :*.::**:****.** *:*:.: : :. . . :: :*:*:**::*: ..:* * . * .: *** ..* . .: . : * . : ..: *. ..: . :.*. *", "identical_positions": 66, "similar_positions": 85, "identity": "23.08%" }, { "cls_id": "homologset.oma.814543", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NC96-1", "uniprot_id": "NECP1_HUMAN", "id": "Q8NC96-1", "name": "Adaptin ear-binding coat-associated protein 1", "aln": "MATELEYESVLCVKPDVSVYRIPPRASNRGYRASDWKLDQPDWTGRLRITSKGKTAYIKLEDKVSGELFAQAPVEQYPGIAVETVTDSSRYFVIRIQDGTGRSAFIGIGFTDRGDAFDFNVSLQDHFKWVKQESEISKESQEMDARPKLDLGFKEGQTIKLCIGNITNKKGGASKPRTARGGGLSLLPPPPGGKVTIPPPSSSVAISNHVTPPPIPKSNHGGSDADILLDLDSPAPVTTPAPTPVSVSNDLWGDFSTASSSVPNQAPQPSNWVQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3T093-1", "uniprot_id": "NECP1_BOVIN", "id": "Q3T093-1", "name": "Adaptin ear-binding coat-associated protein 1", "aln": "MASELEYESVLCVKPDVSVYRIPPRASNRGYRASDWKLDQPDWTGRLRITSKGKVAYIKLEDKVSGELFAQAPVEQYPGIAVETVTDSSRYFVIRIQDGTGRSAFIGIGFSDRGDAFDFNVSLQDHFKWVKQESEISKESQEMDSRPKLDLGFKEGQTIKLSIGNITTKKGGTSKPKTAGTGGLSLLPPPPGGKVTIPPPSSSVAISNHVTPPPIPKSNHGGSDADILLDLDSPAPITTPAPAPVSASNDLWGDFSTASSSVPNQAPQPSNWVQF", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q9CR95-1", "uniprot_id": "NECP1_MOUSE", "id": "Q9CR95-1", "name": "Adaptin ear-binding coat-associated protein 1", "aln": "MAAELEYESVLCVKPDVSVYRIPPRASNRGYRASDWKLDQPDWTGRLRITSKGKIAYIKLEDKVSGELFAQAPVEQYPGIAVETVTDSSRYFVIRIQDGTGRSAFIGIGFTDRGDAFDFNVSLQDHFKWVKQETEISKESQEMDNRPKLDLGFKEGQTIKLSIGNITAKKGGASKPRASGTGGLSLLPPPPGGKVTIPPPSSSVAISNHVTPPPIPKSNHGGNDSDILLDLDSPAPVSTSAPAPVSTSNDLWGDFSTASSSVPNQAPQPSNWVQF", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*************************************************** *******************************************************:**********************:********** ****************.***** ****:***::: *****************************************.*:***********::*.**:***.****************************", "identical_positions": 255, "similar_positions": 15, "identity": "92.73%" }, { "cls_id": "homologset.oma.814590", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q4G061-1", "uniprot_id": "EIF3B_RAT", "id": "Q4G061-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MQDAENVAAPEAAEERAEPARQQPVSESPPTD---EAAGSGGSEVGRTEDAEEDA---EARPEPEVRAKPAAQSEEETAASPAASPTPQSAQ-----EPSAPGKAEAGGEQAR-HPSAR-----AEEEGGSDGSAAEAEPRALENGEADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKIIN--DYYPE--EDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMT--ISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGD---RTSIFWNDV--KDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALWGG-DKFKQIQRFSHQGVQLIDFSPCERYLVTFS------------PLMDTQDDPQAIIIWDILTGHKKRGFHCES------------SAHWPIFKWS--HDGKFFARMT--LDTLSIYETPSMGLLDKKSLKISGIKDFSWSPG-------------GNIIAFWVPEDK--DIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQ----------GVVTNFEIFRMREKQVPVDVVEMK---ETIIAFAWEPNGSKFAVLHGEAPR-ISVSFYHVK-------------SNGKIELIKMFDKQQANTIFWSPQGQFVVLAGLRS---MNGALAFVDTS---------------DCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQDQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRQYRKMAQELYMKQKNERLELRGGVDTDELDSNVDDWEEETIEFFVTEEVIPLGSQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JZQ9-1", "uniprot_id": "EIF3B_MOUSE", "id": "Q8JZQ9-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MQDAENVAVPEAAEERAEPARQQPASESPPTD---EAAGSGGSEVGQTEDAEEDA---EAGPEPEVRAKPAAQSEEETATSPAASPTPQSAERSPSQEPSAPGKAEAVGEQARGHPSAG-----AEEEGGSDGSAAEAEPRALENGEADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKIIN--DYYPE--EDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMT--ISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGD---RTSIFWNDV--KDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALWGG-DKFKQIQRFSHQGVQLIDFSPCERYLVTFS------------PLMDTQDDPQAIIIWDILTGHKKRGFHCES------------SAHWPIFKWS--HDGKFFARMT--LDTLSIYETPSMGLLDKKSLKISGIKDFSWSPG-------------GNIIAFWVPEDK--DIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQ----------GVVTNFEIFRMREKQVPVDVVEMK---ETIIAFAWEPNGSKFAVLHGEAPR-ISVSFYHVK-------------SNGKIELIKMFDKQQANTIFWSPQGQFVVLAGLRS---MNGALAFVDTS---------------DCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQDQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRQYRKMAQELYMKQKNERLELRGGVDTDELDSNVDDWEEETIEFFVTEEVIPLGSQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55884-1", "uniprot_id": "EIF3B_HUMAN", "id": "P55884-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITN--DFYPE--EDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMT--ISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGD---RTSIFWNDV--KDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALWGG-EKFKQIQRFSHQGVQLIDFSPCERYLVTFS------------PLMDTQDDPQAIIIWDILTGHKKRGFHCES------------SAHWPIFKWS--HDGKFFARMT--LDTLSIYETPSMGLLDKKSLKISGIKDFSWSPG-------------GNIIAFWVPEDK--DIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQ----------GVVTNFEIFRMREKQVPVDVVEMK---ETIIAFAWEPNGSKFAVLHGEAPR-ISVSFYHVK-------------NNGKIELIKMFDKQQANTIFWSPQGQFVVLAGLRS---MNGALAFVDTS---------------DCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRGGVDTDELDSNVDDWEEETIEFFVTEEIIPLGNQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A7MB16-1", "uniprot_id": "EIF3B_BOVIN", "id": "A7MB16-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MQDAENVAAPEAAEQRAEPGPEQAAAEPSPGA---EVARPGVQEAAGGEDA-------EAGPGPEGPAEPAADGEGKADATPGATPPPPEES-------SAQLAGEAPAEQAQDAAAEA----------GSEGAGGDPD-GAAEDGGADEPSFSDPEDFVDDVSEEELLADVLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITN--DFYPE--EDGRTKGYIFLEYASPAHALDAVKNADGYKLDKQHTFRVNLFTDFDKYMT--ISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGD---RTSIFWNDV--KDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALWGG-EKFKQIQRFSHQGVQLIDFSPCERYLVTFS------------PLMDTQDDPQAIIIWDILTGQKKRGFHCES------------SAHWPIFKWS--HDGKFFARMT--LDTLSIYETPSMGLLDKKSLKISGIKDFSWSPG-------------GNIIAFWVPEDK--DIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQ----------GVVTNFEIFRMREKQVPVDVVEMK---ETIIAFAWEPNGSKFAVLHGEAPR-ISVSFYHVK-------------NNGKIELIKMFDKQQANTIFWSPQGQFVVLAGLRS---MNGALAFVDTS---------------DCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNSKDRFCQLLWRPRPPTLLSQDQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNARLELRGGVDTDELDSNVDDWEEETIEFFVTEEIIPLGNQE", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "X1WET9-1", "uniprot_id": "X1WET9_DANRE", "id": "X1WET9-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MRDTENMEA------------------------------------------------------------------------------------------------------------------------------------EMEYDDEEEPSFSDPEDFDDDISDQELLGDVLRDKPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITN--EFYPD--ADGKTKGYIFLEYSAPSHAHEAVKNADGYKLDKQHTFRVNLFTDFDKYMS--ICDEWEAPEKQPFKDFGNLRHWMEDPDCRDQYSVIYDSGE---RTGIFANDV--KEPIEVEERARWTETYVRWSPKGTYLATFHQRGIALWGG-EKFKQIQRFSHQGVQLIDFSPCERYVVTFS------------PLMDTKDDPQAIIIWDVLTGQKKRGFHCES------------SAHWPIFKWS--PDGKFFARMT--QDMLSIYETPSMGLLEKKSLKINGIKDFSWSPG-------------DNIIAFWVPEDK--DIPARVTLMQFPSRNEMRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQ----------GVVTNFEIFRMREKQVPVDVVEMK---DSIIAFAWEPNGSKFAVLHGESPR-INSSFYHVK-------------SNGKIDLIKMFDKQQANSIFWSPQGQFLVLAGLRS---MNGALAFVDTS---------------DCTMMNIAEHYMASDVEWDPTGRFVVTSVSWWSHKVDNAFWLWTFQGRLLQKNNKERFCQLLWRPRPPSLLTQEQIKLIKKDLKKYSKIFEQKDRLSQSKASKELVDKRRTMMEEYRKHRKRAMDMYQEQRPLRLELRGGVDTDELDSNVDDWEEETIEFFINEEIIPIGDL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8V0ZC55-1", "uniprot_id": "A0A8V0ZC55_CHICK", "id": "A0A8V0ZC55-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MQGTEDSPAPPGAQGPAEEPEQPDGAPTEPPP---------PQQQLKEEKEEEEREGPEEEGGSEGPPEPPPAASEPPAESQAPQPSSPQPGSGRESPEQAEPKAESLPEEAKSEPPAEAEP-------PAEPCAPREDGEAAPAEPEDELSFSDPEGFVDDISDEELLGDVLKDQPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKIIN--EFYPE--ADGKTKGYIFLEYMSPSHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMT--ISDEWEIPEKQPFKDLGNLRYWLEDPDCRDQYSVIFESGD---RTSIFWNDI--KEPVQIEDRARWTETYVRWSPKGTYLATFHQRGIALWGG-EKFKQIQRFSHQGVQLIDFSPCERYLVTFS------------PLMDTQDDPQAIIIWDILTGQKKRGFHCEN------------SAHWPIFKWS--HDGKFFARMT--SDTLSIYETPSMGLLDKKSLKINGIRDFSWSPG-------------GNIIAFWVPEDK--DIPARVTLMQLPARQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQ----------GVVTNFEIFRMREKQVPVDVVEMK---ESIIAFAWEPNGSKFAVLHGETPR-ISVSFYHVK-------------NNGKIDLIKTFDKQQANTIFWSPQGQFVVLAGLRS---MNGALAFVDTS---------------DCTMMNIAEHYTASDVEWDPTGRYIVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPATLLSEDQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEEFRKYRKMAQELYMEQRNERLELRGGVDTDELDSNVDDWEEETVEFFINEEIITLAEPE", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q0E940-1", "uniprot_id": "EIF3B_DROME", "id": "Q0E940-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MAKKKSEEHSG--------------------------------------------------------------------------------------------------------------------------------TDANDSDYQEEPNFDDPPGFVDNISDEDLLGDMLAQRPSEADGVESVVVVDNIPKVEPVRLEKLKLVINKLFSNYGEIVN--VVYPVD-EEGKTKGYAFMEYKQARQAEEAVKKLNNHRLDKNHTFAVNLFTDFQKYEN--IPEKWEPPTVQTFKVQSDLYNFINDPDTYDQYCVAAETAPNCVQVGFWQNVL--PEPFELETRERFTDTFVKWSPLGTYVVTFHKPGVAIWGG-SSFQKIQKFPHPGTQFVEFSPCENYLVTYG------------PTPTG----QKIIIWDIRTGAEKRSFVADG------------MSVLSMFRWS--HDDKFVARMG--ENSIHIYETPSFYLLDLKSIKIPGIRGFSWSPT-------------DNVIAYWVEEQN--QIPARVTLMEIPKKREIRNKNLFHVADCKLHWQKSGDYLCVKVDRYSKLKKDKKDLDVKFLGMFYNFEIFHMREKEIPVDSVEIR---ELILAFAWEPVGNKFSIIHGETNS-SNVSFYEVN-------------KGVKPSLVKRLEKKSCTHLFWSPRGQFIVMANLT-----MGTFEFVDSTN--------------DYIITASPDHFRASEVEWDPTGRYVVTGVSSWKVKEDTGFNMYTFQGRIIKRTILKNFVQFLWRPRPPTLLSEEKQKEIKKNLKKYYAAFEQKDRLRLTRASKELLEKRSQLRETFMEYRNKRIAEWAEQKSRRIMLRGHVDTDNLET--DEVDEEIVEFLVKEEVTLLE---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9C5Z1-1", "uniprot_id": "EIF3B_ARATH", "id": "Q9C5Z1-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MEVVDIDARAAKLG------------------------------------------------------------------------------------------------------------------------------IDWSQVNFDSIQLPPGEDFGIESDDEAVYQD---DQSEFDTGFGNIIVVDHLPVVPKEKFEKLEGVVKKIYNQLGVIKENGLWMPVDPDTKMTLGYCFIEFNTPQEAQNAKEKSHGYKLDKSHIFAVNMFDDFDRLMN--VKEEWEPPQARPYVPGENLQKWLTDEKARDQ--LVIRSGP---DTEVFWNDTRQKAPEPVHKRPYWTESYVQWSPLGTYLVTLHKQGAAVWGGADTFTRLMRYQHSMVKLVDFSPGEKYLVTYHSQ---------EPSNPRDASKVEIKVFDVRTGRMMRDFKGSADEFSIGGPGGVAGASWPVFRWAGGKDDKYFAKLS--KNTISVYETETFSLIDKKSMKVDNVVDICWSPT-------------DSILSLFVPEQGGGNQPAKVALVQIPSKVELRQKNLFSVSDCKMYWQSSGEYLAVKVDRYTKTKK----------STYSGFELFRIKERDIPIEVLELDNKNDKIIAFAWEPKGHRFAVIHGDQPR-PDVSFYSMKT----------AQNTGRVSKLATLKAKQANALFWSPTGKYIILAGLKG---FNGQLEFFNVD---------------ELETMATAEHFMATDIEWDPTGRYVATAVTS-VHEMENGFTIWSFNGIMLYRILKDHFFQLAWRPRPPSFLTAEKEEEIAKTLKKYSKKYEAEDQDVSLLLSEQDREKRKALKEEWEKWVMQWKSLHEEEKLVRQNLRDGEVSDVEEDEYEAKEVEFEDLIDVTEEIVQES--", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q54QW1-1", "uniprot_id": "EIF3B_DICDI", "id": "Q54QW1-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MTIFDSDEEELVTTLSD-------FEPPVQIDTSFNKFIVVDNIPVAPEAKHEKLKSILVKIYQNRPGAEVVGIHLALD-AQRNTKGFAFIEYSKKESAIDAATSLNNYPLDKSHTLKVNLLDDFSKFAN--FEETYKPPTREDFKPKPNYNQWLSDPKALKGYDQFVTRYG--DYTDICWNEMHVGKPMVEKSSVSLTSSYVQWSNTGSYLVTFHPDGIALYGG-KDWIQVNLFEHRGVQLVDFSPEDKYLITFAP-----------IASDNPNSPKSIVVWDVRSGKKLRSFLAPPKE----------QFTWPAFQWS--AKDKYIARIEQLEKGINIYETPSMNLLDDKIFEVKGIKDFSWSPT-------------DLSLAYFVPAND--PLPAKICLVEMPSKKLLAEKSIWGATDARFHWQNEGAYLCVKTDKVATGKTKKEK------IPTTSFELFRTHEPNVPIESFEIQ---YAIKAFSWEPRGKRICIIHGEFKMNMFVSFFEVQ--------------KTSVKLISKLENRKLNTIFWSPRGTLVLLANLG----DTGELEFYNTQ---------------DCESYGTQEHLQCTGVDWNPSGRYVTTFVSHWKVQTDTGFNIWSFNGDLVYSVLKDRFFQFNWRPRPKFMLTNKEINQIKQNIKKYQEKFDKQDEDDNKAIQHIEQTRLDNLMKEFLSFLQKGEQEYQALEPTRKQLG---SYEDIDPNDIYESIETIEELIDIKTIVLKKIN", "tax_id": 44689, "tax_name": "Social amoeba" }, { "uniprot_ac": "P06103-1", "uniprot_id": "EIF3B_YEAST", "id": "P06103-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MKNFLPRTLKNIYELYFNNISVHSIVSRNTQLK------------------------------------------------------------------------------------------------------------RSKIIQMTTETFEDIKLEDIPVDDIDFSDLEEQYKVTEEFNFDQYIVVNGAPVIPSAKVPVLKKALTSLFSKAGKVVN--MEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRLDLKHRLFLYTMKDVERYNSDDFDTEFREPDMPTFVPSSSLKSWLMDDKVRDQFVLQDDVKT-----SVFWNSMFNEEDSLVESRENWSTNYVRFSPKGTYLFSYHQQGVTAWGG-PNFDRLRRFYHPDVRNSSVSPNEKYLVTFSTEPIIVEEDNEFSPFTKKNEGHQLCIWDIASGLLMATFPVIKSP----------YLKWPLVRWS--YNDKYCARMVG-DSLIVHDATKNFMPLEAKALKPSGIRDFSFAPEGVKLQPFRNGDEPSVLLAYWTPETN--NSACTATIAEVPRGRVLKTVNLVQVSNVTLHWQNQAEFLCFNVERHTKSGK----------TQFSNLQICRLTERDIPVEKVELK---DSVFEFGWEPHGNRFVTISVHEVADMNYAIPANTIRFYAPETKEKTDVIKRWSLVKEIPKTFANTVSWSPAGRFVVVGALVGPNMRRSDLQFYDMDYPGEKNINDNNDVSASLKDVAHPTYSAATNITWDPSGRYVTAWSSSLKHKVEHGYKIFNIAGNLVKEDIIAGFKNFAWRPRPASILSNAERKKVRKNLREWSAQFEEQDAMEADTAMRDLILHQRELLKQWTEYREKIGQEMEKSMNFKIFDVQPEDASDDFTTIEEIVEEVLEETKEKVE-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .. . :**: * : *: : .::.: . * *: *:* * . . .. ** .* : : : *..: . . : * : . :: : . . . * . : .:*::* *:*: : * * : :** : :: : * .: ..** :.*::*: : ::*: :* * . .:*: ..*: *:: . : * .: :: * :: .: .:.::* . :: :. .. : :.* : .: . : ::**... :*..:.:: .. .::: : * ::*:: .*: : *.*** * :: : . :: . : : . : *** * :::. * . : * : . : .: : *:*:**::.: : : : .: ::.: * :: * :: ***** :*: : : : : :::: :: :* . : : : : . : . * : ", "identical_positions": 69, "similar_positions": 199, "identity": "7.55%" }, { "cls_id": "homologset.oma.814591", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GH40-1", "uniprot_id": "A0A8I6GH40_RAT", "id": "A0A8I6GH40-1", "name": "Eukaryotic translation initiation factor 2A", "aln": "MGFSFRDKMAPST----PLLTVRGSEGLYMVNGPPH---FTESTVLPREPGKNCKVYTFSKDGT-LFAWSNGEKVNIINVANKG-----LLHSFDLPKAVCLEFSPNNTVLATWQPYTTSKDGTAGTPNLQLYDVKTGTCLKSFIQ-------KKMQNWCPSWSDDEIICARNVNNEVHFFENNNFNSACFLREPRAMCLKYQEKAPQTCLQSDLIETVPQKVFLDTIANKLHLQKVNDFNLSPGTQPFKVAVYVPGSKGAPSFVRLYQYPNFAGPQAALANKSFFKADKVTMLWNKKATAVLVIASTDVDKTGASYYGEQTLHYIATNG------ESAVVQLPKNGPIYDVAWNPSSTEFCAVYGFMPAKATVFNLKCDPVFDFGTGPRNAAFYSPHGHILVLAGFGNLRGQMEVWD-VKNYKLISKPVASDSTYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSLLYKYDVPSNGELWQVSWQP------------------FLDGIFPAKTITYQAVPSEVPSEEPKVATAYRPPALRNKPVTSSKLHEEEPPQ----NMKPHPSS-----DKPLSKTALKNQRK--------------HEAKKAAKQEARN----DLAPTPVPQSAPRSTVTQSASGD----------------PEVDKKIKNLKKKLKAIEQLKEQAAAGKQLEKNQ-----------------------LEKIQKETALLQELED-LELGV----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJW6-1", "uniprot_id": "EIF2A_MOUSE", "id": "Q8BJW6-1", "name": "Eukaryotic translation initiation factor 2A", "aln": "--------MAPST----PLLTVRGSEGLYMVNGPPH---FTESTVLPRESGRNCKVYTFSKDGT-LFAWSNGEKVNIINVANKG-----LLHSFDLPKAVCLEFSPNNTVLATWQPYTTSKDGTAGTPNLQLYDMKTGACLKSFIQ-------KKMQNWCPSWSDDEIICARNVNNEVHFFENNNFN---------------------------------------TIANKLHLQKVNDFNLSPGTQPYKVAVYVPGSKGAPSFVRLYQYPNFAGPQAALANKSFFKADKVTMLWNKKATAVLVIASTEVDKTGASYYGEQTLHYIATNG------ESAVVQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKATVFNLKCDPVFDFGTGPRNAAFYSPHGHILVLAGFGNLRGQMEVWD-VKNYKLISKPVASDSTYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSLLHKYDVPSNGELWQVSWQP------------------FLDGIFPAKTIKYQAVPSEVPSEEPKVATAYRPPALRNKPVTNSKLHEEEPPQ----NMKPHPGS-----DKPLSKTALKNQRK--------------HEAKKAAKQEARS----DAAPTPVPQSAPRNTVTQSASGD----------------PEVDKKIKNLKKKLKAIEQLKEQAAAGKQLEKNQ-----------------------LEKIQKETALLQELED-LELGV----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A287AUH4-1", "uniprot_id": "A0A287AUH4_PIG", "id": "A0A287AUH4-1", "name": "Eukaryotic translation initiation factor 2A", "aln": "--------MAPSA----PLLTVRGSEGLYLVNGPPH---FTESTVFPRESGKNCKAYTFSKDGT-LFAWGNGERINVINVTTKE-----LLHSFDLPKAVCLEFSPKNTILATWQPYTTSKDGAAGIPNLQLYDMKTGTCLKSFIQ-------KKMQNWCPSWSEDETLCARNVNNEVHFFENNNFN---------------------------------------TIANKLHLKKINDFVLSPGPQPYKVAVYVPGSKGAPSFVRLYQYPNFDGPHAALANKSFFKADKVTMLWNKKATAVLVIASTEVDKTGASYYGEQTLHYIATNG------ESAVVQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKATIFNLKCDPVFDFGTGPRNAAYYSPHGHILVLAGFGNLRGQMEVWD-VKNYKLISKPVASDSTYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSVLHKYDVPSNAELWQVSWQP------------------FLDGIFPEKSITYQAVPSDVPSEEPKVATAYRPPALRNKPVTNSKLHEEEPPQ----NMKPQPGN-----EKPLSKTALKNQRK--------------HEAKKAAKQEARSDKSPDMAPSPAPQNTPRNTVSHSTSGD----------------PEIDKKIKNLKKKLKAIEQLKEQAATGKQLEKNQ-----------------------LEKIQKEKALLQELED-LELGI----", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0AAA9SB04-1", "uniprot_id": "A0AAA9SB04_BOVIN", "id": "A0AAA9SB04-1", "name": "Eukaryotic translation initiation factor 2A", "aln": "--------MAPST----PLLTVRGSEGLYMVNGPPH---FTESTVFPRESGKNCKAYTFSKDGT-LFAWGNGEKINVISVTKKG-----LLHSFDLPKAVCLEFSPKNTVLATWQPYTASKDDTAGIPNLQLYDVKTGTCLKSFIQ-------KKMQNWCPSWSEDETLCARNVNNEVHFFENNNFN---------------------------------------TIANKLHLKKINDFVLSPGPQPYKVAVYVPGSKGAPSFVRLYQYPNFDEPHAALANKSFFKADKVTMLWNKKATAVLVIASTDVDKTGASYYGEQTLHYIATNG------ESAVVQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKATVFNLKCDPVFDFGTGPRNAAYYSPHGHILVLAGFGNLRGQMEVWD-VKKYKLISKPVASDSTYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSVLHKYDVPSNAELWQVSWQP------------------FLDGIFPEKAITYQVVPSDVPSEEPKVATAYRPPALRNKPVTNSKLHEEEPPQ----NMKPQPGN-----EKPLSKTALKNQRK--------------HEAKKAAKQEARIDKSPDMPPAPAQQSTPRSTISQSTSGD----------------PETDRKIKNLKKKLRAIEQLKEQAAAGKQLEKNQVFSAFFIWAHSYYHPSPFYYKQLFNQIKEYIDFKTSFEIRKDRGIRGSW", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q9BY44-1", "uniprot_id": "EIF2A_HUMAN", "id": "Q9BY44-1", "name": "Eukaryotic translation initiation factor 2A", "aln": "--------MAPST----PLLTVRGSEGLYMVNGPPH---FTESTVFPRESGKNCKVCIFSKDGT-LFAWGNGEKVNIISVTNKG-----LLHSFDLLKAVCLEFSPKNTVLATWQPYTTSKDGTAGIPNLQLYDVKTGTCLKSFIQ-------KKMQNWCPSWSEDETLCARNVNNEVHFFENNNFN---------------------------------------TIANKLHLQKINDFVLSPGPQPYKVAVYVPGSKGAPSFVRLYQYPNFAGPHAALANKSFFKADKVTMLWNKKATAVLVIASTDVDKTGASYYGEQTLHYIATNG------ESAVVQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKATIFNLKCDPVFDFGTGPRNAAYYSPHGHILVLAGFGNLRGQMEVWD-VKNYKLISKPVASDSTYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSILHKYDVPSNAELWQVSWQP------------------FLDGIFPAKTITYQAVPSEVPNEEPKVATAYRPPALRNKPITNSKLHEEEPPQ----NMKPQSGN-----DKPLSKTALKNQRK--------------HEAKKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSISGD----------------PEIDKKIKNLKKKLKAIEQLKEQAATGKQLEKNQ-----------------------LEKIQKETALLQELED-LELGI----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5ZKC1-1", "uniprot_id": "EIF2A_CHICK", "id": "Q5ZKC1-1", "name": "Eukaryotic translation initiation factor 2A", "aln": "--------MAPPA----PLLAVRGSEGLFMVNGPPS---FTESAVFQRDSGRNCKAVAFSKDGS-LFAWCNGEKVNIVNVTSAG-----LLRSFDLPKVVCLEFSPKNNILATWQAYSAAKDGTAGAPNLQLYDVKTGKCLKSFIQ-------KKMQNWCPCWADDESICARNVNNEVHFFENNNFN---------------------------------------TIANKLHLQKVNDFVLSPGAQPTKVAVYVPGSKGAPSFVRLYQYPNFGGPQSALANKSFFKADKVTMLWNKKATAVLVIASTDVDKTGASYYGEQTLHYIATNG------ESAIVQLPKNGPIYDVVWNPNSVEFCAVYGFMPAKATVFNLKCDPVFDFGTGPRNAAYYSPHGHILVLAGFGNLRGQMEVWD-VKNYKLISKPVASDSTYFAWCPDGEHIVTATCAPRLRVSNGYKIWHYTGSVLHNYEVPSNEEMWQVSWQP------------------FLDGVFPVKAVKYQAVPSELPSAEPKPAQAYRPPALRNKPVTSSKLHEDEPPQ----NMKPQSGSS----EKPLSKTALKNQKK--------------HEPKKAAKQEAKADCSQESTQSSASQNTPRSAVPVVTSGD----------------PEIDKKIKNLKKKLKAIEQLKEQAAAGKQLEKNQ-----------------------LEKIQKESALLQELED-LELGL----", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9VNX8-1", "uniprot_id": "EIF2A_DROME", "id": "Q9VNX8-1", "name": "Eukaryotic translation initiation factor 2A", "aln": "--------MAAAADLVVPTLAIRSSVAVELWSSAGSKQPFEHKPHLPREETKSSRSICFSSNGR-YFAYSNGQEVKVLQASRDSAASWPVICVLPRPKAFYLQFSPRGSYLCTWEHYAITKDRPEGSPNLLVYEVATGVEVFAIVQ-------KNQADWQPSWSADESIFALVVGGEALFYDLGEGAEKG----------------------------------FATTSRKIGGSRGGMLSLGPGNCPPFLAFYTPGAKGAPSMCKLYKYPALGQNQ-TVACKSFFQADRVEMLWNKRGSGLLLLTSTEVDKSGASYYGNQAVHFMATKG------DTCSVPLSKEGPVHCVKWSPKATEFVVVYGFMPSKAALYNLKCDVVFDFGEGPRNCAYFNPFGNLIALAGFGNLPGAVEVWD-VSKREKLANLKCADTTVFEWHPNGEWFVTATTAPRLRISNGFKVYHYSGALLHETMWPQGQELLGIEWQQ------------------FADKTFSEPKITKAKHEGIKSSQPEASKKAYTPPHLR--LLKEGKNPEKYLPQPSIPGLAPTAAAGGVNGNKRNNKNKQRSARKDVNVVNGGDADSAPTEVVDQAAPVARQSPVFVAAEERKPQHTPRQKYQPDNAADQPPNSYGQGHPNGQHISDKERKIRSVAKKLSDIKKLKVRRSQGENLELNQ-----------------------LNKIKMEAQYLDELKALKQSA-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9CAT3-1", "uniprot_id": "Q9CAT3_ARATH", "id": "Q9CAT3-1", "name": "Eukaryotic translation initiation factor 2A", "aln": "--------MSSSPS---LEILVREAEGFTVWNGPPF----TNGQPTLKLERVSCSNTKFSVDGSKLMAMKSDGVISIYDATSLT-----EVRSFTIANVTAAELSPCGTYLQTFQKPTTPQEKNVSIWNTETGDLAHSHYQKSITK-------ASWPSIR--FCPDESSACRLATNEVQFFDPKDFS--------------------------------------KGITSRIRVPGIAAFELSKTP-ASHVAVFVPESKGSPGSVQIFGCGEELQSQ-PSARRSFFRCSSVQFSWNHGSTGLLVVVQSDVDKTNQSYYGETKLHYLTIDGT-----HEGLVPLRKEGPVHDVQWSFSGSEFAVVYGFMPACVTIFDKNCKPLMELGEGPYNTLRWNPKGRVLCVAGFGNLPGDMAFWD-VVNKKQLGSNKAEWSVTSEWSPDGRYFLTASTAPRRQIDNGMKIFNYDGKRYYKKMFER---LYQAEWKP------------------ESPERFGDISELIKSVESLKLGEGK-------------------------------------------------SQGQGSAQKK-----------------TIAPNPIAQKPAAYRPPHAKHAAAVQAELLGISTTGEMS-----------------KNALKNKKKRENKKAAAAAAAASGSNNA----------------------------------------------------", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "P53235-1", "uniprot_id": "EIF2A_YEAST", "id": "P53235-1", "name": "Eukaryotic translation initiation factor 2A", "aln": "----------MSS-----QFFLKTSQDIELFQSYPT---FEQSNTNSKD--FPVISSVLSPCGR-FLALSTKENVKVFTGPCLDN----VLLTMKLSDVYDLHFSPAGNYLSTWERASIQDPNHKNVKVWYLNKPFKKDCVSEDIVPAYEYQAKSQSGWFLQFSKLDNYGLRLFKHDLKIVKLSSANADN-----------------------------FDFQSPFAVLSDDETSQHFTTYLISPAEHPTICTFTPEKGGKPAQLIIWALS-EGKITKKIASKTFFKADSCQLKWNPLGNAILCLAITDFDSSNKSYYGENTLYLLSFQGVNGTLGGNSVRVSLTTGPVHDFTWSPTSRQFGVIAGYMPATISFFDLRGNVVHSLPQQAKNTMLFSPSGHYILIAGFGNLQGSVEILDRLDKFKCVSKFDATNTSVCKWSPGGEFIMTATTSPRLRVDNGVKIWHVSGSLVFVKEFKE---LLKVDWRSPCNYKTLENKDEAFFENHIINNWEPLPDSTTSSLDPKISNKSELQIHSSVQEYISQHPSREASSNGNGSKAKAGGAYKPPHARRTGGGRIVPGVPPGAAKKTIPGLVPG-------MSANKDANTKNRRRRANKKSSETSPDSTPAPSAPASTNAPTN----------NKETSPEEKKIRSLLKKLRAIETLKERQAVGDKLEDTQ-----------------------VLKIQTEEKVLKDLEKLGWKDE----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : :: : . : .. . : :* * :* . :.: . : : .. .:** .. * *:: : . . . . . :. : : : . . * :. :.* * *. :: * ::**:.. : ** ...:* :. ::.*.:. ****: :: :: .* . **:: . *. .. :* .: *:**: :.:: . . : .: . * :.* *. : :****** * : . * : : : :.. . : * *.*. ::**: :** ::.** *::: * . : .*: . . :. . : . . . .. ::. *: : *.: ", "identical_positions": 55, "similar_positions": 144, "identity": "7.39%" }, { "cls_id": "homologset.oma.814631", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q62931-1", "uniprot_id": "GOSR1_RAT", "id": "Q62931-1", "name": "Golgi SNAP receptor complex member 1", "aln": "MAAG----TSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSARDGGRDRYSSDTTPLLNGSSQD--------RMFETMAIEIEQLLARLTGVNDKMAEYTHSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLK-EHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIHSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVIGICTILLLLYAFH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88630-1", "uniprot_id": "GOSR1_MOUSE", "id": "O88630-1", "name": "Golgi SNAP receptor complex member 1", "aln": "MAAG----TSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSGSRDGGRDRYSSDTTPLLNGSSQD--------RMFETMAIEIEQLLARLTGVNDKMAEYTHSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFTAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLK-EHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIHSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVIGICTILLLLYAFH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95249-1", "uniprot_id": "GOSR1_HUMAN", "id": "O95249-1", "name": "Golgi SNAP receptor complex member 1", "aln": "MAAG----TSSYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDRYSSDTTPLLNGSSQD--------RMFETMAIEIEQLLARLTGVNDKMAEYTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLK-EHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIHSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVIGICTILLLLYAFH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A4X1U194-1", "uniprot_id": "A0A4X1U194_PIG", "id": "A0A4X1U194-1", "name": "Golgi SNAP receptor complex member 1", "aln": "MAAG----TSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSARDGRRDRYSSDTTPLLNGSSQD--------RMFETMAIEIEQLLARLTGVNDKMAEYTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFVAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLK-EHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIQSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVVGICTILLLLYAFH-", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q2TBU3-1", "uniprot_id": "GOSR1_BOVIN", "id": "Q2TBU3-1", "name": "Golgi SNAP receptor complex member 1", "aln": "MAAG----TSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSARDGRRDRYSSDTTPLLNGSSQD--------RMFETMAIEIEQLLARLTGINDKMAEYTSSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFVAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLK-EHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIQSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVIGVCTILLLLYAFH-", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "E9QFW9-1", "uniprot_id": "E9QFW9_DANRE", "id": "E9QFW9-1", "name": "Golgi SNAP receptor complex member 1", "aln": "MAGG----NSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSSS--RDGRRGDSSSDTTPLLCNSTQD--------RMFETMSVEIEQLLAKLTGVNDKMAEYTSTPGVTSLNAALMHTLQRHRDILQDYTHEFHKTKSNFMAIREREDLLGSVRKDIETYKSGSGVNNRRTELFLK-EHEHLRNSDRLIDDTISIAMATKENMTSQRGLLKSIQSRVNTLANRFPAINNLIQRINLRKRRDSLILGGVIGICTILLLLYAFH-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O22151-2", "uniprot_id": "GOS12_ARATH", "id": "O22151-2", "name": "Golgi SNAP receptor complex member 1-2", "aln": "MTESSLDLQESGWEELRREARKIEGDLDVKLSSYAKLGARFTQG-DTDLVMNYEKVLKCVLVSGYVDTGSPTVGSGRSWKSMEMEIQSLLEKLLDINDSMSRCAASAAP---TTSVTQKLARHRDILHEYTQEFRRIKGNINSLREHAELLSSVRDDISEYKASGSMSPG--VQVLR-ERASIHGSISHIDDVIGQAQATRAVLGSQRSLFSDVQGKVKNLGDKFPVIRGLLGSIKRKRSRDTLILSAVIAACTLFLIIYWLSK", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "P38736-1", "uniprot_id": "GOSR1_YEAST", "id": "P38736-1", "name": "Golgi SNAP receptor complex member 1", "aln": "MSSQ------PSFVTIRGKAISLETQTESLLSKYSTFAQTTSSE-----------------QTGQEKK-------------IDKQLEGILGQRQDVIDSLTQICD--SNPAISASKLSQLHRHKEILQDHWKSFRNIRSSIQQERNRLNLLFSVKNDIANSTTDAPAPIGDADEYIQNETRRIDQSNNVVDRLISQAWETRSQFHSQSNVLNTANNKVLQTLQRIPGVNQLIMKINTRRKKNAFVLATITTLCILFLFFTW---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : :* :* .:* : : * .::.: : . . : ::: :* : .: *.::. . .:: * **::**::: :.*:. :..: *:: :*: **:.** .:.. :: * : * :: *. * *: : ** .::. :.:: :::* :. *: *: :: :::::*. : * ::*:: ", "identical_positions": 32, "similar_positions": 91, "identity": "12.12%" }, { "cls_id": "homologset.oma.814632", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q62931-1", "uniprot_id": "GOSR1_RAT", "id": "Q62931-1", "name": "Golgi SNAP receptor complex member 1", "aln": "MAAGTSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSARDGGRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTHSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLM-GSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIHSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVIGICTILLLLYAFH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9QFW9-1", "uniprot_id": "E9QFW9_DANRE", "id": "E9QFW9-1", "name": "Golgi SNAP receptor complex member 1", "aln": "MAGGNSNYWEDLRKQARQLENELDLKLVSFSKLCTSYS--SSRDGRRGDSSSDTTPLLCNSTQDRMFETMSVEIEQLLAKLTGVNDKMAEYTSTPGVTSLNAALMHTLQRHRDILQDYTHEFHKTKSNFMAIREREDLL-GSVRKDIETYKSGSGVNNRRTELFLKEHEHLRNSDRLIDDTISIAMATKENMTSQRGLLKSIQSRVNTLANRFPAINNLIQRINLRKRRDSLILGGVIGICTILLLLYAFH-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VE50-1", "uniprot_id": "GOSR1_DROME", "id": "Q9VE50-1", "name": "Golgi SNAP receptor complex member 1", "aln": "-MGGSS--YDVLRKQARSLENEIDLKLVAFSKIGAGSG--GGGSGGLG--GVDTSPLLG----EHVFDSLSEEIEQMLEKLSSLNESMSDLPASG------AAAMHTLQRHREILQGYRQEFNKICANHTMRIEREELLRGSGLATSSGSPSISGLNRR--EMYLKESGHLNSASHLVNDQINIAIETRDHLHAQRQAFKRLQTRFNDISNRFPLISSLIQRINIKKRRDSLILGAVIGFCVILLLLYAFN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9LMP7-1", "uniprot_id": "GOS11_ARATH", "id": "Q9LMP7-1", "name": "Golgi SNAP receptor complex member 1-1", "aln": "--MDVPSSWDALRKQARKIEAQLDEQMHSYRRLVSTKALSKSDGNESD---------------------LEAGIDLLLRQLQQVNAQMQAWVSSGG----SEMVSHTLTRHQEILQDLTQEFYRHRSSLRAKQEHASLLEDFREFDRTRLDLEDGYGSE--QALIKEHMGINRNTAQMDGVISQAQATLGTLVFQRSTFGGINSKLSNVASRLPTVNTILAAIKRKKSMDTIILSLVAAVCTFLIFIYWITK", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :: ******.:* ::* :: :: :: : . . .. . : *: :* :* :* .* : *** **::***. :** : :. *: .*: . .* . . : :** :. :: *. * * : ** : ::::.. ::.*:* :..:: *: :* *::**. * ..*.:*:::* : ", "identical_positions": 44, "similar_positions": 78, "identity": "17.46%" }, { "cls_id": "homologset.oma.814636", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q62931-1", "uniprot_id": "GOSR1_RAT", "id": "Q62931-1", "name": "Golgi SNAP receptor complex member 1", "aln": "MAAGTSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSARDGGRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTHSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIHSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVIGICTILLLLYAFH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9QFW9-1", "uniprot_id": "E9QFW9_DANRE", "id": "E9QFW9-1", "name": "Golgi SNAP receptor complex member 1", "aln": "MAGGNSNYWEDLRKQARQLENELDLKLVSFSKLCTSYS--SSRDGRRGDSSSDTTPLLCNSTQDRMFETMSVEIEQLLAKLTGVNDKMAEYTSTPGVTSLNAALMHTLQRHRDILQDYTHEFHKTKSNFMAIREREDLLGSVRKDIETYKSGSGVNNRRTELFLKEHEHLRNSDRLIDDTISIAMATKENMTSQRGLLKSIQSRVNTLANRFPAINNLIQRINLRKRRDSLILGGVIGICTILLLLYAFH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.*.********************************* *:*** *. ******** .*:********::*******:************ :.**.****************************:*********:*:********:*******************:*********::*****************:****:*::*********:*.*********************************", "identical_positions": 218, "similar_positions": 25, "identity": "87.2%" }, { "cls_id": "homologset.oma.814666", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q7PLI2-1", "uniprot_id": "NIPB_DROME", "id": "Q7PLI2-1", "name": "Nipped-B protein", "aln": "MGERDNPTVPVTTLAGLTSTSDLLSELPVADSLQSAASLNKSLLFHALVANESSNLLSMRNENLVRQLVTAIERTNSDNIELIHCPVQDTATNCSTYPELLQGIYHFRPAVFNTSIKIHSPDQHTANARLEAKKMQIDSYSIPECYASPTNLSISNEHQLQDAQACFNQLTSMTSKEILEEFSQINFKENATEKDKIDVIENSDLNVTKILSQNTLKKKSNTPERSTVQSIQEQFFIQQQEANYNLKHDLNQVSTNVGQIQNISDTFPQEPSNFNLNSVNIPNMLYVQSPPFTESEPTQAHHSSIEYLKKKKSQILDVSILNRQQVLENTSLHIINKSSTYQTNQNVSTTTSTSTSSSGKSQVRVCINRLSIEDSRLMQQSIKKFVQKSPELARSMGLLQETCQQQHENLNIIPTSAEECVLESRASSTNNTVKIPIDTFSTIKADEKRSAKRKLAISIGDIPPEQIFSKPKMRRVERITPLSNTKCVKEEVTRSQTYQQFIRNMDHIIEILDDSESPNFDSEDVDETIECISSKLLNSMSTDVAKLKAKQALDSIPKNKLTLLINYAMRNVYLARNYFAGTEDEDEFVDDEVIEKLLNAMDACLLICNIYSTVSDLQFLQEDNVSHIIKFTQFQLRETIFPLHDPVYTAKSIKRTTHRKKIKSHQAQNRSMQLFYLKTVELLKVFVTLFDKCVFVDTIVLPLSTLAIEPFFVDNIETLQFVCLELVTTIFRKERYDKIRNSILGDILTSIDRLPSSKKNLRPYKLTNNGG-NIQMVTALVLQLIQCATILPDSLCDNGKFSNKPQEGNTFDEEGKKLLQPSQDLLVLQKYDVAVSIGGNFLTTFLNKCKSR--SNETDFRPLFENFIHDLLATVNKPEWPASELLLSLLGTMLVRYVSDKGIEQSIRLVSLDYLGIVAARLRKDTVESRCRVNIIDSMIQSIKLEQEKEGDVTSNNDQFDLEPEEQRTDFLQKILLDFLAVNAQ--EENLIWDYARHFYLAQWYRDVIYQRRRINDGKKGLAFRKSKIRNNRRTNGDYLDTSDSGSCD-ESDTDTNKKRIHCVDSNDFELNINIYKALEARKQYFINKIKPFSVFGEQNHSSNQHIKTYIDYNNAQLIAQYLATKRPFSQSFDGCLKKIILVVNEPSIAVRTRAMKCLANIVEVDPLVLKRKDMQMGVNQKFLDTAISVREAAVDLVGKFVLSNQDLIDQYYDMLSTRILDTGVSVRKRVIKILRDICLEYPDFSKIPEICVKMIRRVHDEEG-IQKLVTEVFMKMWFTPCTKNDKIGIQRKINHIIDVVNTAHDTG---TTWLEGLLMSIFKPRDNMLRSEGCVQEFIKKNSEPPMDIVIACQQLADGLVDRLIELEDTDNS----RMLGCITTLHLLAKVRP------QLLVKHAITIEPYLNIKCHSATAAKFICAVADILEKVVPLVNNASESFLASLEEHLMLLVVSR-NQAEVTSCVSCLGALVNKITHNFKLIRDCFQKFYRVLDVSRSQVIQGNNSVDNIYTPSFRRSLFTIGILMRYFDFKSPIALGETNDGLPVSICEDVFHCLMFFCRCTNQEIRKQALISLGSFCVLNDGYLTRSELKNLYCEILSSIANDAGFKIICMRNIWIYLTESEMFMHNKEKEWEKQSKHEDLKEMNDVSSGMASR-----IIQLYLEEILECFLNRDDTVRLWAVKVIQIVLRQGLVHPVRMVPYLICLSTDHRIESAHRADALLKDIDKTYSGFVNMKVQFGLQLCFKLQKILQINNRGKLEIIRGYASR----GPDNTTTALN------DFLYTLLRTTKPQRRALVQTVTKQFDD---QKTSLQQMLYIADNLAYFPYVVQDEPLYLIHQIDLLISMAGTHLLATFKEHIKPS---DKEGDVLEDDDDVEDPEVLFNRLPEDLTEIIKCITSAQACMLLLILKDHLKEMYAITDSKISRYSPSEQKLYEKAVTRKSVNDFNPKTTIDVIKKQMSQEKLSTDINFTLTKEEKLDLVVKYLDFKQLMLKLDPDDGDSDADESRDKTMLNISASSDGVAFSSSAKNSHSACDGYSLTVTDVVD-VPMSHIAKASMLTSKPSGRKTNPVRTKKKRRKIDSTDDETSDAEYA-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A5HEI1-1", "uniprot_id": "SCC2_ARATH", "id": "A5HEI1-1", "name": "Sister chromatid cohesion protein SCC2", "aln": "------------------------------------------------MSNPSSSGLGSSS-----------------------------------------GLTHFGIGLANTVQSEVTP------------YLPLPSLPIFCGAAEPG------EFKLFDEVGQGSGYRSLDRSEILAQSSRIANMLHETDVSYLDLRN-----------------EARAPDCNSGEHFQLYDLVLR---------------CNPGAFEYVTPGPTCDP------------LFTNEGPQKIISEPSVPVK-----MQRQTDTHLARSIEPEPVKRVLRPNHVEDHSWQHETLTNQSPKDVTAYDSRPETITMNELSASKKPKGKKKRKDDLSSVQPDPSVLQES-IVQNFCEMLEDFCGRAEVPGDDRDEAEWSSVPVDEVRVLINELMTIRS----------------------------KMLLHMVPVD------------------------------------------------ILSRLLRTLDHQIHRAEGLSIYSEHSDSDSVLLVLGALESIHASLAVMANSDMPKQLYKEEIIERILEFSRHQMMAV---MSAYDPSYRTGSKPAENLAFEGDDDDDNPDHDMGSASKRRRIVKNSKVKKASVNRISG-AVNTALQKLCTILGLLKDLLLVERLSDSCILQLLKTSITTFLVENIQILQLKAISLIGGIYN--SYSQHRTYVIDEISQLLWKLPSSKRALRAYLLPDEEQRQIQMVTALLIQLVHNSTSLPETSR-------QAASGNSILETSVDVG------YLTKCHEAATETCCLFWTRVLERFTSFKGQDASEIKLIIENLVMDLLTALNLPEYPSVSPILEVLCVILLHNAGLKSKDVSARIMAIELLGTIAARLKRDAVLCSK-----DRFWTLLESDSEISVDQVCTKDCTFCLGKRAGNLLVCQICQRRFHGDCLGLKELDISSRNWHCPLCVCKRQLLVLQSYCKTDTKGTGKLESEESIENPSMITKTEVVQQMLLNYLQDVGSADDVHTFICWFYLCLWYKDVPKSQNKFKYYIARLKAKSIIRNSGATTS-----FLTRDAIKQITLALGMNSSFSRGFDKILNMLLASLRENAPNIRAKALRAVSIIVEADPEVLCDKRVQLAVEGRFCDSAISVREAALELVGRHIASHPDVGIKYFEKVAERIKDTGVSVRKRAIKIIRDMCTSNPNFSEFTSACAEILSRISDDESSVQDLVCKTFYEFWFEEPPGHHTQFASDASSIPLELEKKTKQMVGLLSRTPNQQLLVTIIKRALALDFFPQAAKAAGINPVALASVRRRCELMCKCLLEKILQVEEMSREEGEVQVLPYVLVLHAFCLVDPGLCTPASDPTKFVITLQPYLKSQADSRTGAQLLESIIFIIDSVLPLIRKLPLSVTEDLEQDLKHMIVRHSFLTVVHACVRCLCSVSKLAGKGVSIVEHLLQFFFKRLEAQGSDNTQIAG-----------RSLFCLGLLIRHGNSLISTSGGKNFN------LSGCLNLFKRHLRTEDIALKVRSLQALGFILIARPEYMLEEDIGKIIETTLADEANGR-MKMQALQNMYEYLLDAEKQLGSEKASDNTVNSVEQGGHNVPVAAGAGDTNICGGIVQLFWDKILGRCLDFDDQIRQTSLKIVEVVLRQGLVHPITCVPYLIALETDPQEANQKLAHHLLMNMHEKYPAFFESRLGDGLQMSFIFMQSISQVTSEPNQSLQQKGSTNMLGKNDHASSTLTQARLGVSRIYKLIRGNRVSRNKFMTSIVRKFDNPTWNGSVISFLKYCTETLALLPFTSPDEPLYLVYSINRVMQIRAGAVESNLKALLHKDSAKTQHGNGAYQQDPIPGHMNMMDLNTRIQEEPRHWNSYGHATLIDLNGSVYQDSRDQFTSYQVHNGKADVHKMTSSDPPELSTDDLQ-KIQVDCLAAIAIQLLLKLKRYLKVTYSLNDDRCQAYSPTEPLKPGDPLSRQSVAFDLSETRTDLPSTYQDLVQRYQEFKNAMREDTVDFTIYSTNVKRKRPTPRKTSRSAKKTVAYNEDDDDDDNDDRGWHGGGGRGAARRLNYSTRSSNRR", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* **. *. . *: ** .: ** . :* : : * .* *.* *.:* * . . *: .*** : *:* : *: . :*: : ::.:*: .: : :* :: : * * :: :: . :* :: :.* ***: . : ::::.. * ** . . *: ::* ::* * *.. *: .* :: . :. . ..: ::. . ** .*.: :. ::*: *: .: . ...:: . :* . : *:: *: : **:: : : ::.*:. * *:**.::. :: : :. . .. .... .**: *:..:: : :*.:: .:: .:*:**::*: :: :. * .: .: :. : * : :. ... . : * :.:: ** . :: .. ::: * :* :: *: : *: :* * . :* .*:*:**: **: .:.*: *:. *.: *. ::.:* : :*****: **.* *.:: :*******::**:: :* **:: :. .**:: * . .: : : ::.*.. * * .*:: .* .: :::: ::**:: ***:::* **:*: . :*.:* .:*:: .. *. : * *::::: ** :****::*:* . * : :: :.* . * ...:* :. . :: :* : :. :* * . * *. *::: : : ..** . :*: :. : :. :. : .*..: .. : : * : : : :*:* ::*. *:: :.. ::. :: : : *: *. : .**:.** *: :: :.* : :*::*::.:: ***.** ** * :*:.*: :* *:********::***:.: *: *: :*:: :: ** *********.***:**:* . *:**::.. *.::: *: *:*. :*.** :.* ::** . :.. . . ::: :.::: : : *: : * * . : *. . .: *: :.. *:::::::*: ... ::* : .** :. * * . .*..**::***: :..* *.*::: :: *::.*:**:.: . *. .**:.* ::* : : * :** ** :: : :...::.. :* *:: *:.. *: * . **** :*:*:*: : . : *:. : .. :: : . * : :: ::* :** : : . *: ..:: :: *:. **. :*: .::*:: ** ::* : .:: . :. .. *: . *::* .. *:**: ::** *: ** :* ::*::::*********: *****.*.** : . : *. ** ::.:.*..*.: :: ***:.* : : :. . : :: .* *:::::*. . :*.*:* .: .*. :: ::.::**: : : :. : * ::.** :*:. ******::.*: ::.: . : :.:* :: . :.*: ::* : . ::: .. * : : .:* :: * . : .. :*. :: . ... :*: .. .. *.:*:: * :* : * *. . :.:* . : * * : * . . * *. :* * : .. :.. : :. .::: *:* * .: :. * .: . ... : ...: : .. . : :*: ", "identical_positions": 374, "similar_positions": 749, "identity": "17.58%" }, { "cls_id": "homologset.oma.814669", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K0J4-1", "uniprot_id": "A0A0G2K0J4_RAT", "id": "A0A0G2K0J4-1", "name": "Nipped-B protein", "aln": "MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNSRIAEEVNCLLACRDDNLVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRY-VQSGMMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAPQSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPRHGSSDDYLHMVHRLSSDDGDSSAMRNAASFPLRSPQPVCSPAGSDGTPKGSRPPLILQSQSLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKDQNEKAAMYDIISSPTKDSTKLTLRLSRVRSSDMDQQEDMLSGMENSNVSENDIPFNVQYPGQTSKTPITPQDVNRSLNAAQCLSQQEQTAFLPANQVPVLQQNTSVATKQPQTSVVQNQQQVSQQGPI--YDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALMVSIDLHQAGRADSQASLTQDSDNIKKPEETKQCNDAPISVLQEDSVGSLKSIPENHPETPKNKSDPELSKSEMKQNESRLSESKPNENQLGESKSNESK-LETKTETQTEELKQSENKTTESKQSESAVVEPKQNENRLCDTKPNDNKQNNTRSENTKARPETPKQKAESRPETPKQKSEGRPETPKQKGDGRPETPKQKSEGRPETPKQKGEGRPETPKHRHENRKDSGKPSTEKKPDVSKHKQDIKSDSSRLKSE-RAEALKQRPDGR--SESLRRDHDSKQKSDDRGESERHRGDQSRVRRPETLRSSSRNEHS----TKSDGSKTEKLERKHRHESGDSRDRPS-GEQKS----RPDSPRVKQ---GDTNKSRP---GFKSPNSKDDKRTEGNRSKVDSNKAHTDNKAEFPSYLLGGRSSALKNFVIPKIKRDKDGNITQETKKMDMKGEQKDKVEKMGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDREEKSR-SSLKSLKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHDGRRSSGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFKRFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDVDGEPMYIQMVTALVLQLIQCVVHLPSSEKDPNSEEDSNKKVDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQWFRDTTLETEKAMKSQKDEESSDGAHHAKEIETTGQIMHRAESRKRFLRSIIKTTPSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVEHILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVTQNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLEDFKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNSILSDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTEVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKRKERKTSPAKENES-------SESEEEVCRPRKSRKRVDSESDSDSEDDVNSVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKTGVHFHPKQTLDFLRSDMANSKLTEDVKRSIVRQYLDFKLLMEHLDPDEEEEEGEVSASTNARNKAITSLLGGGSPKNNPAADTEDEESDGEDRGGGTSGSLRRSKRNSDSTELAAQMNESVDVMDVIAICCPKYKDRPQIARVVQRTSSGVSVQWMAGSYSGSWTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6KCD5-1", "uniprot_id": "NIPBL_MOUSE", "id": "Q6KCD5-1", "name": "Nipped-B-like protein", "aln": "MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNSRIAEEVNCLLACRDDNLVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRY-VQSGMMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAPQSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPRHGSSDDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSDGTPKGSRPPLILQSQSLPCSSPRDVPPDILLDSPERKQKKQKKIKLGKDEKDQNEKAAMYDIISSPTKDSTKLTLRLSRVRSSDMDQQDDMLSGMENSNVSENDIPFNVQYPGQTSKTPITPQDVNRPLNAAQCLSQQEQTAFLPANQVPVLQQNTSVATKQPQTSVVQNQQQVSQQGPI--YDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALMVSIDLHQAGRVDSQASITQDSDSIKKPEETKQCNDAPISVLQEDIVGSLKSIPENHPETPKKKSDPELSKSEMKQNESRLSESKPNENQLGESKSNESK-LETKTETPTEELKQNENKTTESKQSESAVVEPKQNENRPCDTKPNDNKQNNTRSENTKARPETPKQKAESRPETPKQKSEGRPETPKQKGDGRPETPKQKSEGRPETPKQKGEGRPETPKHRHENRRDSGKPSTEKKPDVSKHKQDIKSDSPRLKSE-RAEALKQRPDGR--WESLRRDHDSKQKSDDRGESERHRGDQSRVRRPETLRSSSRNDHS----TKSDGSKTEKLERKHRHESGDSRDRPS-GEQKS----RPDSPRVKQ---GDTNKSRP---GFKSPNSKDDKRTEGNRSKVDSNKAHTDNKAEFPSYLLGGRSGALKNFVIPKIKRDKDGNITQETKKMDMKGEQKDKVEKMGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDREEKSR-SSLKSIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHDGRRSSGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFKRFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRVDPHGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDVDGEPMYIQMVTALVLQLIQCVVHLPSSEKDPNSEEDSNKKVDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQWFRDTTLETEKAMKSQKDEESSDATHHAKELETTGQIMHRAENRKKFLRSIIKTTPSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVEHILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVTQNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLEDFKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNSILSDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTEVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKRKERKTSPAKENES-------SESEEEVSRPRKSRKRVDSESDSDSEDDINSVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKTGVHFHPKQTLDFLRSDMANSKLTEDVKRSIVRQYLDFKLLMEHLDPDEEEEEGEVSASTNARNKAITSLLGGGSPKNNTAADTEDEESDGEDRGGGTSGSLRRSKRNSDSTELAAQMNESVDVMDVIAICCPKYKDRPQIARVVQRTSSGVSVQWMAGSYSGSWTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8C2N1I0-1", "uniprot_id": "A0A8C2N1I0_CRIGR", "id": "A0A8C2N1I0-1", "name": "Nipped-B protein", "aln": "MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNSRIAEEVNCLLACRDDNLVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRY-VQSGMMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAPQSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGSLRNIHDNKVSGPLSGNSANHHADNPRHGSSDDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSDGTPKGSRPPLILQSQSLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKDQNEKAAMYDIISSPTKDSTKLTLRLSRVKSSDMDQQEDMLSGMENSNVSENDIPFNVQYPGQTSKTPITPQEVNRPLNAAQCLSQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQVSQQGPI--YDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALMVSIDLHQAGRVDSQASITQDSDSIKKPEEMKQCNDAPISVLQEDIIGSLKSIPENHPETPKKKSEPELSKSEVKQNESRLSESKPNENQLLETKSSESK-LETKTETQTEELKQNENKTTECKQNESTVVEPKQSENRLCDAKPNDNKQNNTRSETTKSRPETPKQKAESRPETPKQKGEGRPETPKQKGEGRPETPKQKGEGRPETPKQKGEGRPETPKHRHENRRDAGKPSTDKKPDVSKHKQDIKSDSPRLKSE-RAEALKQRPDGR--SESLRRDHDSKQKSDDRGESERHRGDQARVRRPETLRSSSRNEHS----IKSDGSKTEKLERKHRHESGDSRDRLSSGEQKS----RPDSPRVKQ---GDTNKSRP---GFKSPNSKDDKRTEGNRSKVDSNKAHTDNKAEFPSYLLGGRSGALKNFVIPKIKRDKDGNITQETKKMDMKGDQKDKVEKMGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDREEKSR-SSLKSIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRSSGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFKRFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDVDGEPMYIQMVTALVLQLIQCVVHLPSSEKDPNSEEDSNKKVDQDVLITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQWFRDTTLETEKAMKSQKDEESSDGAHHAKEIETTGQIMHRAENRKKFLRSIIKTTPSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVEHILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVTQNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLEDFKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNILSDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQLYLKQVLEAFFHNQSNVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINDDGKDPVRGFRQDESSSALCSHLYTMIRGNRQHRRAFLISLLNLFDDTAKTEVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKRKERKASPTKENES-------SESEEEVSRPRKSRKRVDSDSDSDSEDDVNSVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKTGVHFHPKQTLDFLRSDMANSKLTEEVKRSIVRQYLDFKLLMEHLDPDEEEEEGEVSASTNARNKAITSLLGGGSPKNNTAAETEDDESDGEDRGGGTSGSLRRSKRNSDSTELAAQMNESVDVMDVIAICCPKYKDRPQIARVVQKTSSGFSVQWMAGSYSGSWTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q6KC79-1", "uniprot_id": "NIPBL_HUMAN", "id": "Q6KC79-1", "name": "Nipped-B-like protein", "aln": "MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDNLVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRY-VQSGMMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAPQSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPRHGSSEDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSEGTPKGSRPPLILQSQSLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTLRLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCLSQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQISQQGPI--YDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALMVSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETPKKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENK-LETKVETQTEELKQNESRTTECKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRLKSE-RAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRVRRPETLRSSSRNEHG----IKSDSSKTDKLERKHRHESGDSRERPSSGEQKS----RPDSPRVKQ---GDSNKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNFVIPKIKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDREDKSR-SSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRSSGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFKRFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQCVVHLPSSEKDSNAEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQWFRDTTLETEKAMKSQKDEESSEGTHHAKEIETTGQIMHRAENRKKFLRSIIKTTPSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVEHILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVTQNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLEDFKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNILSDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTDVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKRKERKSSPSKENES-------SDSEEEVSRPRKSRKRVDSDSDSDSEDDINSVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEEGEVSASTNARNKAITSLLGGGSPKNNTAAETEDDESDGEDRGGGTSGSLRRSKRNSDSTELAAQMNESVDVMDVIAICCPKYKDRPQIARVVQKTSSGFSVQWMAGSYSGSWTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1BKC4-1", "uniprot_id": "E1BKC4_BOVIN", "id": "E1BKC4-1", "name": "Nipped-B protein", "aln": "MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDNLVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRY-VQSGMMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAPQSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNLHDNKVSGSLSGNSANHHADNPRHGSSDDYLHMVHRISSDDGDSSTMRNAASFPLRSPQPVCSPAGSDGTPKGSRPSLILQSQSLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKDQNEKAAMYDIISSPSKDSTKLTLRLTRVRSSDMDQQEDMLSGMENSNVSENDIPFNVQYPGQTSKTPITPQDVNRPLNAAQCLSQQEQTAFLPANQVPVLQQNTSVATKQPQTSVVLNQQQVSQQGPI--YDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALMVSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDTPISVLQEDIIGNLKSTPENHPETPKKKSDPELLKSEVKQNESRLAESKPNENRLVETKSSETK-LETKIEVPTEEPKQNENRMIESRQNESSTAEPKQNENRLPDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDGRPETPKQKGDGRPETPKQKGEGRPETPKQKNEGRPETPKHRHENRRDSGKPSTEKKPEVSKHKQDIKSDSPRLKSE-RAEALKQRPDGRSISESLRRDHDSKQKSDDRSESERHRGDQSRVRRPETLRSSSRNDHG----IKSDGSKPDKLERKHRHESGDSRERPSSGEQKS----RPDSPRVKQ---GDSNKSRPDKPGFKSPNSKDDRRTEGNKSKVDSNKTHPDNKAEFPSYLLGGRSGALKNFVIPKIKRDKDGNITQETKKMEMKGEQKDKVEKMGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDREDKSR-SSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSDETFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRSSGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFKRFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQCVVHLPSSEKDSNSEEDSNKKVDQDVIITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQWFRDTTLETEKAMKSQKDEESSEGSHHAKEVETTGQIMHRAENRKKFLRSIIKTTPSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVEHILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVTQNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLEDFKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNILSDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTEVNMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKRKERKSSPGKENES-------SESEEEVSRPRKSRKRVDSDSDSDSEDDINSVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKTGVHFHPKQTLDFLRSDMANSKITEDVKRSIVKQYLDFKLLMEHLDPDEEEEEGEVSASTNARNKAITSLLGGGSPKNNAAAETEDDESDGEDRGGGTSGSLRRSKRNSDSTELAAQMNESVDVMDVIAICCPKYKDRPQIARVVQKTSSGFSVQWMAGSYSGSWTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1NJ66-1", "uniprot_id": "F1NJ66_CHICK", "id": "F1NJ66-1", "name": "Nipped-B protein", "aln": "MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNGRIAEEVNCLLACRDENLVSQLIHSLNQVSTDHIELKDNLGSDDPEGDTPVLLQAILARNPNVFREKSMQNRYGVQSGMMIPQFNISQNSMRGSPASSNYQQTTISHSPSSRFVPPQTSSGNRFLAQQNSPVPSPYAPQSPAGYMPYSHPPSYTPHPQLQQA---CPIVTAGMRNLHENKVSSQLSGNSANHHADNSRHGSNEDYLQMVHRLSSDDGDPS-IRNAASFSLRSPQSVCSPAGSDGTPKGSRPPLILQSQPPPYSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKDQTEKAAMYDIISSPSKDSTKLTLRLSRVRSSDLDQQDDMLSGLENSSVSEGDIPFNVQYPGQTSKTPVTPQDVNRPLNAAQCLPQHEQTAFLQAQQVPVLQQNTSVAAKQPQTPVVQTQQQVSQQGTITSYDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQENKPQEAGGAAGGNRPASQESGSAGNGARPALMVSIDLQQAGRADSQATITQEFEAIKKPEEIKQYNDGFVCIPQEETVGVLKLKPENHPEIFRKKSDFEVQKTDIQQNENRQMEFQQNESRRLESKYNDNKQVEAKYDIKHD------SRQMEMKQNENRQAESKQNESRQMEMKQNEGKQNNGKQEIRQ----------------------------------RPETPKQKSEGRPETPKQKSEGRPETPKHRHDNRRDSSKPLSEKKIELSRHKPDVKSDTSKVKSDSRSDPVKQRPDGRSVSDTQRRDHDSLKQRSEDRESERYKGDPSKIRRTEFLRSSNRNEHDSKYGIKSDGSKPEKFERKHRHDSGESRERFSSGDQKSDQKSRPDSPRVKQDGKGDSSKSRPDKPGFRSPNSKDERRTDSSKSKVESNKAHPDNKAEFPSYLLGARSGALKHFVIPKIKRDKDGNVTQESRKTELKGEQKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKFIKDREDKSRGSCFKPNKNKSSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSEEAFESSRKRHKKDRDEAWEYEEHDRRSSGDHRRSGHYHEGRRTSGSGRYRNRSPDDSDLDDYSPPPSLSEVARKMKKKEKQKKRRAYEPKLTPEEMMDSSTFKRFIASIENILENLEDMDFTTLGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKIVKVLNILEKNIQDGSKLSTLLNHNNDTEDEERLWRDLIMERVTKSADACLTAINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRVDPLGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDTDGEPMYIQMVTALVLQLIQCVVHLPSAEKDSNSDEELNKKVDQDVLITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFIQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQGSIARILKQASGGEDDIQQLQKALLDYLDENTETDASLVFSRKFYIAQWFRDTTMETEKAIKSQKDEDSSEGTHHAKDVETTGQIMHRAESRKKFLRSIIKTAPSQFSTLKIYSDTVDYEDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARPDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPHHDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDASYKPVKKACTQLVDNLVEHILKYEESLSDSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLATKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGSVVNKVTQNYKFVWACFNRYYGALSKLKSQHQEDPNSTILTANKPALLRSLFTVGALCRHFDFDHEDFKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKTLYNSILSDKNCSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDISSGMSSSIMQLYLKQVLEAFFHTQSNVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPSMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCPKDPVRGFRHDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTEVNMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKKKERKPSSDEETESDSNSGSESESEEEASKPRRLRKRVDSDSDSDEENDINAVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEDGEVSASTNARNKAITSLLGGGSPKNN-AAETEDDESDGEDRGGGTSGSLRRSKRNSDSTELASQMNESVDVMDVIAICCPKYKDRPQIARVVQKTSNGFSVQWMAGSYSGSWTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******************************************.**************:******:************************* ******:***.************* ******:.*:::*****:.*******************************:.************************.***.***:*** .***:..:**:*:****. ************.****.:***:****:******.* :******.*****.*******:********.******. * ************************:*******:*.************:**********:**:***:***:**:**:***.***.****************:***::**.*******.*:****** *:************:*****.** .***:****.* ******************************************:. *******:*********:**:***:**********:****.****::**: : ****** ** ** :.: **: :* ** ****** ::**: *: *::::*.*.* * : **.: *:* .:.* :*:* : : .: * :*.*. .*.**.*.* : * *:.**** :.* : ********.*.********.***********:**:*:.** ::** ::*:** * ***:.::**: *::.:******* :: *****. :: .: ****::** :::**.* ****.**:*. ***.**.:*:******:**:**:* * *:*** ********* **:.***. **:**.***::**:..:***::**:*.************.**.***:*************:***::* ::**: ******:**************************:*****:*** *.:*. ***.*************************************************************:*:*********** *:******:************* *:***:**.********.***::************************:******************** *******:********::**************************************** ****************************:**********************:*******************************************:** ********************************************************************************************************************** **************************:***.*::*: ***:****:***************************************:******************************************************************** *****.*****:*******************.******************:*****:******:**:.:****::***********.**:********:********: ******:********************************************************** **************************************************************************************************************:****************************************:***************************:*****************************************:*************************************************************:********:*************:************.* * :********************** *******************************************************.***.******.********************************************:**********************.**.************************************:*************************************** ********:************:**************************:*.**************************************************:****.*. :*.** *:****..:**: ******:****.*:*:*:************************************************************************************:**:******:*******************:************************** **:***:****************************:******************************:**.*.*********************************************************************", "identical_positions": 2397, "similar_positions": 276, "identity": "84.76%" }, { "cls_id": "homologset.oma.814720", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K0J7-1", "uniprot_id": "A0A0G2K0J7_RAT", "id": "A0A0G2K0J7-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase", "aln": "MTQHAPRKWVRSERRVKPVSEREQQCRRRPRWAPRPERPVFSFLTSVVTVRAARWVTMEAPPL-AGVPTECTPAVAGAEVRCPGPAPLRLLEWKVTAGATVRIGSVLAVYEAAVSAQPAGPAPARAASGGCVRASRTERRLRSERAGVVRELCAQPGQVVAPGALLVRLEGCSHPVVMKGLCAECGQDLTQLQSKNGKQQVPLSTATVSMVHSVPELMVSSEQAEKLGREDQQRLHRNRKLVLMVDLDQTLIHTTEQHCPQMSNKGIFHFQLG-RGEPMLHTRLRPHCKDFLEKIAKLYELHVFTFGSRLYAHTIAGFLDPEKKLFSHRILSRDECIDPFSKTGNLRNLFPCGDSMVCIIDDREDVWKFAPNLITVKKYVYFPGTGDVNAPPGARESQTRKKVNHSSKGADILEQALPVKDPEEGKP-PGVEQ-SNGLGKASRELNGG-------EAVP---GVFSSKTDEKETWSLTRASPASSSGGRELTEAPELPVSCEWDSRTAPGAHPTQGD-ATQGLDFDLSSDSESSESS-RSEGQKSFSSASDGENEERRRRKKSPATQDRTK--VPQHSGPHDTSGGRSAASPSGESGP-LHPHDKVSDPDTQEEGERDSLCGLGNGSVDRKEAETESQNSEQSGVTAGESLDQSVGEEEE---EDTDDDDHLIHLEEILVRVHTDYYTKYDRYLNKELEEAPDIRKIVPELKSKVLADVAVIFSGLHPTNFPVEKTREHYHATALGAKVLTQLVLSPDAPDRATHLIAARAGTEKVRQAQECKHLHVVSPEWLWSCLERWDKVEEQLFPLMDEDTRTHRDNSPAVFPDRHSMLPTALFHPTPIHSKAHPGPEVRIYDSNTGKLIRMGTQGP-------APALSSAPLIHGEPSSFRAVQPHQQQMFGEELPESQDGEQPGPARRKRQPSMSETMPLYTLCKEDLESMDKEVDDILGEGSDDSESEKKKAEDQDSEQERARKPRKPRAPGTR-REQPAGLPSPGERSAAGTRAPRGHKRKLNEEDAASESSGESSNDDEEGSSSEADEMAAALEAELNDLM----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TSG2-1", "uniprot_id": "CTDP1_MOUSE", "id": "Q7TSG2-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase", "aln": "---------------------------------------------------------MEAPPA-AGVPTECTPAVAGAEVRCPGPTPLRLLEWKVAAGATVRIGSVLAVCETAASAQPAGPAPARAASGGCVRAARTERRLRSERAGVVRELCAQPGQVVAPGALLVRLEGCSHPVVMKGLCAECGQDLTQLQSKNGRQQVPLSTATVSMVHSVPELMVSSEQAEKLGREDQQRLHRNRKLVLMVDLDQTLIHTTEQHCPQMSNKGIFHFQLG-RGEPMLHTRLRPHCKDFLEKIAKLYELHVFTFGSRLYAHTIAGFLDPEKKLFSHRILSRDECIDPFSKTGNLRNLFPCGDSMVCIIDDREDVWKFAPNLITVKKYVYFPGTGDVNAPPAARETQARRKVNHSSKGGDALEQALSVRDPEDGRPAPGVEH-SNGLGKASRELNGG-------EAVP---GVFPSKADEKEAWPLTRASPASSSSGHEPTEAPELPVSCEWDGRTTPGVQPTQGDAATQDLDFDLSSDSESSESSSRSEGQR------------------APAPQERTKA-APEHSGPQDTSGGRAAASPLGESGPSIHPHDKGSDLDTQEEGERDSLCGLGNGSVDRKEAETESQNSEQSGVTAGESLDQSVGEEEE---EDTDDDDHLIHLEEILVRVHTDYYTKYDRYLNKELEEAPDIRKIVPELKSKVLADVAVIFSGLHPTNFPVEKTREHYHATALGAKVLTQLVLSPDAPDRATHLIAARAGTEKVRQAQECKHLHVVSPDWLWSCLERWDKVEEQLFPLIDDDTRTHRDNSPAVFPDRHSVLPTALFHPTPIHSKAHPGPEVRIYDSNTGKLIRMGPQGS-------APAPSSAPLNHGEPSSFRAVQPHQQQMFGEELPESQDGEQPGPARRKRQPSMSEAMPLYTLCKEDLESMDKEVDDILGEGSDDSDIEKKKPEDQDNEQERAPKPRKPRAPGIR-REQPVGLPSSGERSTPGMRGPRGHKRKLNEEDAASESSGESSNDDEEGSSSEADEMAAALEAELNDLM----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5B0-1", "uniprot_id": "CTDP1_HUMAN", "id": "Q9Y5B0-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase", "aln": "---------------------------------------------------------MEVPAA-GRVPAEGAPTAAVAEVRCPGPAPLRLLEWRVAAGAAVRIGSVLAVFEAAASAQSSGASQSRVASGGCVRPARPERRLRSERAGVVRELCAQPGQVVAPGAVLVRLEGCSHPVVMKGLCAECGQDLTQLQSKNGKQQVPLSTATVSMVHSVPELMVSSEQAEQLGREDQQRLHRNRKLVLMVDLDQTLIHTTEQHCQQMSNKGIFHFQLG-RGEPMLHTRLRPHCKDFLEKIAKLYELHVFTFGSRLYAHTIAGFLDPEKKLFSHRILSRDECIDPFSKTGNLRNLFPCGDSMVCIIDDREDVWKFAPNLITVKKYVYFQGTGDMNAPPGSRESQTRKKVNHS-RGTEVSEPSPPVRDPEGVTQAPGVEP-SNGLEKPARELNGS-------EAATPRDSPRPGKPDERDIWPPAQAPTSS----QELAGAPEPQGSCAQGGRVAPGQRPAQGA-TGTDLDFDLSSDSESSSES---EGTKSSSSASDGESEGKRGRQKPKAAPEGAGA-LAQGSSLE--PGRPAAPSLPGEAEPGAHAPDKEPELGGQEEGERDGLCGLGNGCADRKEAETESQNSELSGVTAGESLDQSMEEEEE---EDTDEDDHLIYLEEILVRVHTDYYAKYDRYLNKEIEEAPDIRKIVPELKSKVLADVAIIFSGLHPTNFPIEKTREHYHATALGAKILTRLVLSPDAPDRATHLIAARAGTEKVLQAQECGHLHVVNPDWLWSCLERWDKVEEQLFPLRDDHTKAQRENSPAAFPDREGVPPTALFHPMPVLPKAQPGPEVRIYDSNTGKLIRTGARG--------PPAPSSSLPIRQEPSSFRAVPPPQPQMFGEELPDAQDGEQPGPSRRKRQPSMSETMPLYTLCKEDLESMDKEVDDILGEGSDDSDSEKRRPEEQEEEPQ-------PRKPGTR-RERTLGAPASSERSAAGGRGPRGHKRKLNEEDAASESSRESSNEDE-GSSSEADEMAKALEAELNDLM----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RWS7-1", "uniprot_id": "F1RWS7_PIG", "id": "F1RWS7-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase", "aln": "---------------------------------------------------------MEAPPG-GRVPTEGAPPPAVAEVRCPGPGPLRLLEWKVAAGAAVRIGSVLAVCEAATSAQPAGPAPARASSGSCVR---TERRLRSERAGVVRELCAQPGQVVVPGAVLVRLEGCSHPVVMKGLCAECGQDLTQLQSKNGKQQVPLSTATVSMVHSVPELMVSSEQAEKLGREDQQRLHRNRKLVLMVDLDQTLIHTTEQHCQQMSNKGIFHFQLG-RGEPMLHTRLRPHCKEFLEKIAQLYELHVFTFGSRLYAHTIAGFLDPEKKLFSHRILSRDECIDPFSKTGNLRNLFPCGDSMVCIIDDREDVWKFAPNLITVKKYVYFQGIGDINAPSGPREPQARK------RGADVTEQPASVKDPEEGRQASGVEQ-SNGLGKSARELNGG-------TAPRG-AWPWSGQEEERGSRPTSRGSSAC----------------AQQRGRTLPEKRPGRGP-AGPDLDLDVQGDSGSSSSD--SEGQP------------------SPGASDGES--GDKRTRRKPRDTGSAIERPLGVKHCGEPMPG--VQLDVQEEGGRDGLCGLGGGSADRKEAETESQNSEQSGVTAGESLDQSAEEEEEGEEEDADDDDHLVHLEEILARVHSDYYAKYDRFLCGETQEAPDIRKIVPELRSRVLADVAIIFSGLHPTNFPIEKTREHYHATALGARILTQLVLDPDDPDRPTHLIAARAGTEKVRQAQECGQLHVVNPDWLWSCLERWDKVEEQLFPLQDDHGRGQREDCPAAFPDRQGVLPTTLCHPTPVHPRAPPGPEVRIYDASTGKLIRKGAVG---------PGPPGSLPVHTELSSFRAVQPHQQQMFGEDSPDNQDGEQPGPSRRKRQPSMSEAMPLYTLCKEDLESMDKEVDDILGEGSDDSDSEKKKPDDPEEPGP---KSGELGALRAQ-RGHTLKSAPPSERHAADGRGPRGHKRKLNDEDAASESSGASSCEDEEGGSSEADEMAAALEAELGDLM----", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A8V0Y1D0-1", "uniprot_id": "A0A8V0Y1D0_CHICK", "id": "A0A8V0Y1D0-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase", "aln": "---------------------------------------------------------MEEPAEKGGGSAAEGPAALIAEIRAPGPRPLRLLEWKVSVGAAVQIGSVLALCAPLPPAPRPAAASPGSGASPRPQRSSTERKLKAERPGVVRELCARPGQVIAPGGVLVRLEGCSHPVVMKGLCAECGQDLTQIRSKNGKQNVPLSTATVSMVHSVPELKVSSEQAEQLGREDQQRLHRNRKLVLMVDLDQTLIHTTEQHCQQMSNKGIFHFQLG-RGEPMLHTRLRPHCKEFLEKIAKLYELHVFTFGSRLYAHTIAGFLDPEKKLFSHRILSRDECIDPFSKTGNLRDLFPCGDSMVCIIDDREDVWKFAPNLITVKKYVYFQGIGDINAPPGSREIQMKKKINHSAKPEAQDSAVTLAKDADEMKNVTCTEEQNNGLKKATKDMCTANGNTSVSSETPACDLSSHGKVNTQDSLSDSTDDKTDSEITNNLSSTKESQISSEQVERTVLEKQRTQEK--TSDLDFELSSDSESEGGL---DTRKSSTSVSDSENEEKRSWKKSKQPLQDENLQQGSCTDVSEKKDGQVNHSEGTESLPSENILDK-TDIDVQEESEQESVCDLGNGCADKKEAETESQNSEQSGITMGESLDQSMEEEEE--EDDTDDDDHLMHLEEILVRVHTDYYTKYDKYLKKEIEEIPDIRKIVPELKSKVLADVTIIFSGLYPTNFPIEKTREHYHATALGAKIVKNLVLSADDPDKATHLIAARTGTEKVRQAQDCKDLHVVNPDWLWSCLERWDKVEEQLFPLKDDYIKTHRENSPATFPDTHSTFQTALFHPTPIHPKSQPGPEVRLYDPNTGKLIRKSSQTSGQSMYIQSPTPPITLPVHGEHSSFRVVQPHQQQIFEEDLPVTENEEQPGPSKRKRQPSMSETMPLYTLCKEDLESMDKEVDDILGEGSDESDSEKKKPEEKGEKPQISATEATGVKTDQRPRSSSSSLSSSSSEKSLTGSVPRGHKRKLDEDDAASESSKESSNEDEEGSSSEADEMAAALEAELNDFM----", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9W147-1", "uniprot_id": "Q9W147_DROME", "id": "Q9W147-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase", "aln": "---------------------------MQNIPDEEGATPSRAPGGVAASGAAEGDDGGGGSGAKNSASGNSNNNTSGGGIIVLRAALGENEARAVINKWRVREGQFVSAAQILFLYQPVGVDAKDAKDAGKPGGDCAIQRYKSQRAGVVKKRLRKEGELLTKGDAILELSECIHTTVIKDMCADCGADLRQNENGQ------TSEASVPMVHTMPDLKVTQKLAQKLGHDDTRRLLADRKLVLLVDLDQTVIHTTNDTVPDN-IKGIYHFQLYGPHSPWYHTRLRPGTAEFLERMSQLYELHICTFGARNYAHMIAQLLDPEGKFFSHRILSRDECFNATSKTDNLKALFPNGDSMVCIIDDREDVWNMASNLIQVKPYHFFQHTGDINAPPGLSKHELDG------EGVDFKEITEKHGDKDKTESSSEVKPEDTDKGDNTVTSTSK---------------DDDVNEESVDVFEIEGDAKDP-------------EVSNASSATEAPKEPRDKLNGKTNAEDIVVIDDSSSGSPD-----------------------------------------------AEKAASDGEDVVVIDDNSKESTKAEVPPTPAEKNEVVASSTTSPDEK---RPSADADVATTSKTPSLRAPLEGQKQ--IEIEDPDDYLLYLEVILRNIHKRFYSIYD-----ETTEIPDLKVIVPKIRSEVLRGKNLVFSGLVPTQMKLEQSRAYFIAKSLGAEVK------PNIDKEITHLVAVNAGTYKVNAAKKEPAIKVVNANWLWTCAERWEHVEEKLFPLDRKVRNKGRQPPAHCHSPEHVVNYSERSEISPSSSKQQEEQSGNFRETLNPLLVFT------------------NADIESMNKDYETFFESDSSSDEGPVNFENPPMDKKLLKRKREDDNSNRAHDFFTRSDDIMIGAPNLVEVDISSNEEADDNNEKEDDDDEMPS-----------------------------------AKFRRGEDLPSDLELGSESNSEKEPEDEDDGEWNMMGAALEREFLGLEDFDM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : . . * *: *..:: . . . :: :::*.***:: : *:::. * ::.*. * *..*:*.:**:** ** * .. : * *:*.***::*:* *:.: *::**::* :** :*****:******:****:: : ***:**** .* ****** :***::::*****: ***:* *** ** :**** *:***********::. ***.**: *** ***************::*.*** ** * :* **:***.. : : . . * : . .: ... . : : : : *: : .** * . :: : . . *.* * ::: : : ** . ::: : * **:*::** ** .:*. :*: ** * * **:: ***:::*.** . ::**** **:: :*::* :: *.:***.: .: .. ***:*..:** ** *:. ::**..:***:* ***::***:**** . . *: . .. . : . * .: . .: :. . *: . ..:... : . : : :***: . *: : .:*: :: :: ...:::: ::.: :: . .: :: : .* *. *. : * ...* : *. *** *: .: ", "identical_positions": 221, "similar_positions": 237, "identity": "20.77%" }, { "cls_id": "homologset.oma.814721", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q03254-1", "uniprot_id": "FCP1_YEAST", "id": "Q03254-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase", "aln": "-MTTQIRSPQGLPYPIQIDKLIPSVGSYLHEGDRLLVYKFWYLVERASDTGDDDNEHDVSPGGSAGSNGVSPPTKQLRESIEFFESPYEGDLISWNVDVGDEVATANQVICEIKRPCNHDIVYGGLCTQCGKEVSADAFDGVPLDVVGDVDLQISETEAIRTGKALKEHLRRDKKLILVVDLDQTIIHCGVDP---TIAEWKNDPNNPNFETLRDVKSFTLDEELVLPLMYMNDDGSMLRPPPVRKCWYYVKVRPGLKEFFAKVAPLFEMHIYTMATRAYALQIAKIVDPTGELFGDRILSRDENGSLTTKSLAKLFPTDQSMVVVIDDRGDVWNWCPNLIKVVPYNFFVGVGDINSNFLPKQSTGMLQLGRKTRQKSQESQELLTDIMDNEKKLQEKIDKEVKRQEEKLNHQLATAEEPPANESKEELTKKLEYSASLEVQQQNRPLAKLQKHLHDQKLLVDDDDELYYLMGTLSNIHKTYYDMLSQQNEPEPNLMEIIPSLKQKVFQNCYFVFSGLIPLGTDIQRSDIVIWTSTFGATSTPDIDYLTTHLITKNPSTYKARLAKKFNPQIKIVHPDWIFECLVNWKKVDEKPYTL--IVDSPISD---------------------------EELQNFQTQLQKRQE------------YLEETQEQQHMLTSQENLN-------LFAAGTSWLNNDDDEDIPDTASDDDE-------------------DDDHDDESDDENNSEGIDRKRSIEDN-----------------HDDTSQKKTKAEPSQDGPVQHKGEG--------------------------------------DDNEDSDSQLEEELMDMLDD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q75JA4-1", "uniprot_id": "Q75JA4_DICDI", "id": "Q75JA4-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase", "aln": "MISANVEYP--FTEPGKLQQWRYSVGDKFDKGSIIGIFN------------SSKNQSELN-----------------------LISQYDGIIKSILINDTKKELNKGDELYNIEY-CTHDIQFSGLCATCGRELTDTQES--LSILHGHSHLTVSHKEAQRIGDINTKRLLMEKKLSLVLDLDHTVIHAVTEQGFNSSPEWRNKDKNKN------------------GIHTITVNGPMN---------YCIKKRPHLVKFLTEVNKIYELHIYTMGTRNYANEIAKLIDPESSIFKERILSRDDGNGINFKSLQRLFPCDDSMVLIVDDRSDVWKKSKNLIQISPYVYFTDVVDS----LHHEKQPLLQQKLKEQQEQQQQQQQQQQQQQQQQQNKETTETTEKTEKTETTEITEKTDLDNKENQENKTTTTTTTTTTTTTTDSNNTNENEKGNEEEEEESDKVDCHLLIILDKLQKIHRLYYESKDKGGSP--HVIDLVEIVKKDILKGTYIVFSGVYPLGTPIQKQPLRWLAEEFGSVVQNDINNETTHVIAQRKG--TSKVNKALSKGLKVISPQWLIESTRIWQMADEDDFSLPTDIDSPITATSSNGGSVVNDGTATSGGGSGKDAPLVEEDEETKANLEKVAANLITGGVLDALYNDDADKELEDFLDGESDADSQGSRSSNASANSSDYENDEDEDDDDEQNNQDNSTAAVVDNNNNNNNNNNNNNNNNNNNNNNNNNNNNVNDKEIVKNSSIGVNNISKKRKRGDLRSNSSSSSSSSSSSSSNGSISSKSNGHHSSSSSSSSNSSVSSGSSDDENDDSSSVNGDSSNANQDDNDDIANFLEAELDKFIE-", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 184, "similar_positions": 294, "identity": "21.45%" }, { "cls_id": "homologset.oma.814774", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "M0RCA3-1", "uniprot_id": "M0RCA3_RAT", "id": "M0RCA3-1", "name": "Zinc finger protein-like 1", "aln": "----------------------------------------------------MGLCKCPKRKVTNLFCFEHRVNVCEHCLVANHAKCIVQSYLQWLQDSDYNPNCRLCNTPLASRETTRLVCYDLFHWACINERAAQLPRNTAPAGYQCPSCNGPIFPPANLAGPVASALREKLATVNWARAGLGLPLIDEVISPEPEPLNSSDFSDWSSFNATTTPVQEERESTAAAPVFYSQVPRPPPSPSRPEQHTVIHMGSTEALTHA--PRKVYDTRDDDRTAGVHGDCDDDKYRRRPALGWLAQLLRSRAGSRKRPLTLLQRAGLLLLLGLLGFLALLALMSRLGRAAADSDPNLDPLMNPHIRVGPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DB43-1", "uniprot_id": "ZFPL1_MOUSE", "id": "Q9DB43-1", "name": "Zinc finger protein-like 1", "aln": "----------------------------------------------------MGLCKCPKRKVTNLFCFEHRVNVCEHCLVANHAKCIVQSYLQWLQDSDYNPNCRLCNTPLASRETTRLVCYDLFHWACINERAAQLPRNTAPAGYQCPSCNGPIFPPANLAGPVASALREKLATVNWARAGLGLPLIDEVISPEPEPLNSSDFSDWSSFNATTTSVQEERASTPSAPAFYSQAPRPPPSPSRPEQHTVIHMGSTEALAHA--PRKVYDTRDDDRTAGIHGDCDDDKYRRRPALGWLAQLLRSRAGSRKRPLTLLQRAGLLLLLGLLGFLALLALMSRLGRAAADSDPNLDPLMNPHIRVGPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A9J7FNE3-1", "uniprot_id": "A0A9J7FNE3_CRIGR", "id": "A0A9J7FNE3-1", "name": "Zinc finger protein-like 1", "aln": "MALWRHQSAPHPEETWQRRDNQSGWSRREQSFSYRSGSTQSPTFCASHHRSVMGLCKCPKRKVTNLFCFEHRVNVCEHCLVANHAKCIVQSYLQWLQDSDYNPNCRLCNTPLTSRETTRLVCYDLFHWACINERAAQLPRNTAPAGYQCPSCNGPIFPPANLAGPVASALREKLATVNWARAGLGLPLIDEAISPEPEPLNSPDFSDWSSFNATSPAAQEEIDSTSVAPTFYGQVPCPPSPPNCPEQHTVIHMASTEALTHA--PRKVYDTRDDDRTAGFHGDCDDDKYRRRPALGWLAQLLRSRTGSRKRPLTLLQRAGLLLLLGLLGFLALLALMSRLGRAAADSDPNLDPLMNPHIRVGPS", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q2YDD3-1", "uniprot_id": "ZFPL1_BOVIN", "id": "Q2YDD3-1", "name": "Zinc finger protein-like 1", "aln": "----------------------------------------------------MGLCKCPKRKVTNLFCFEHRVNVCEHCLVANHAKCIVQSYLQWLQDSDYNPNCRLCNIPLAARETTRLICYDLFHWACLNERAAQLPRNTAPAGYQCPSCSGPIFPPTNLAGPVASALREKLATVNWARAGLGLPLIDELVSPEPEPLNTSEFSDWSSFNASGSPEQEETASASAAPAFYSQVPRPPASPSRPEQHTVIHMGNPEPLTHASAPRKVYDTRDDERAPGLHRDCDDDKYRRRPALGWLAQLLRSRAGSRKRPLTLLQRAGLLLLLGLLGFLALLALMSRLGRAAADSDPNLDPLMNPHIRVGPS", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1RQT4-1", "uniprot_id": "F1RQT4_PIG", "id": "F1RQT4-1", "name": "Zinc finger protein-like 1", "aln": "----------------------------------------------------MGLCKCPKRKVTNLFCFEHRVNVCEHCLVANHAKCIVQSYLQWLQDSDYNPNCRLCNVPLATRETTRLICYDLFHWACLNERAAQLPRNTAPAGYQCPSCSGPIFPPANLAGPVASALREKLATVNWARAGLGLPLIDEMASPEPEPLNTSEFSDWSSFNASSSPTQEETASASAAPAFYSPVPRPPASPSRPEQHTVIHMGSSEPLTHASAPRKVYDTRDDARVPGLHGDYDDDKYRRRPALGWLAQLLRSRAGSRKRPLTLLQRAGLLLLLGLLGFLALLALMSRLGRAAADSDPNLDPLMNPHIRVGPS", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "O95159-1", "uniprot_id": "ZFPL1_HUMAN", "id": "O95159-1", "name": "Zinc finger protein-like 1", "aln": "----------------------------------------------------MGLCKCPKRKVTNLFCFEHRVNVCEHCLVANHAKCIVQSYLQWLQDSDYNPNCRLCNIPLASRETTRLVCYDLFHWACLNERAAQLPRNTAPAGYQCPSCNGPIFPPTNLAGPVASALREKLATVNWARAGLGLPLIDEVVSPEPEPLNTSDFSDWSSFNASSTPGPEEVDSASAAPAFYSQAPRPPASPGRPEQHTVIHMGNPEPLTHA--PRKVYDTRDDDRTPGLHGDCDDDKYRRRPALGWLARLLRSRAGSRKRPLTLLQRAGLLLLLGLLGFLALLALMSRLGRAAADSDPNLDPLMNPHIRVGPS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ********************************************************* **::******:*********:*********************.******:******************************* ********:.:*********: .. ** *:. **.**. .* **..*. *********...*.*:** ********** *..*.* * ***************:*****:**********************************************************", "identical_positions": 265, "similar_positions": 30, "identity": "72.8%" }, { "cls_id": "homologset.oma.814784", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K4Z5-1", "uniprot_id": "SF3A1_MOUSE", "id": "Q8K4Z5-1", "name": "Splicing factor 3A subunit 1", "aln": "----MQAGPVQAVPPP------PPVATESKQPIEEEASSKEDPTPSKP---------VVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGK--------AQEPSAAIPKVMQQQQQATQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPR----EVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEED--QEKAEETP----SQLD---------------------QDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDR---SIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGV--EETAIGKKIGEEE-IQKPEEKVTWDGHSGSMARTQ-QAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKP-NEIPQQPPPPSSATNIPSSAPPITSVPRPPAMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIA-PMPPIIHAPRINVVPMPPA--APPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPPSKKLKTED-SLMPEEEFLRRNKGPVSIKVQVPNMQDKTEWKLNGQGLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGI-FIKDSNSLAYYNMASGAVIHLALKERGGRKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZQM0-1", "uniprot_id": "D3ZQM0_RAT", "id": "D3ZQM0-1", "name": "Splicing factor 3A subunit 1", "aln": "----MQAGPVQAVPPP------PPVVTEPKQPNEEEASSKEDSTPSKP---------VVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGK--------AQEPSAAIPKVMQQQQQATQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFAKLKKEAENPR----EVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEED--QEKTEETP----SQLD---------------------QDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDR---SIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGV--EETAIGKKIGEEE-IQKPEEKVTWDGHSGSMARTQ-QAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKP-NEIPQQPPPPSSATNIPSSAPPITSVPRPPAMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIA-PMPPIIHAPRINVVPMPPA--APPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPPSKKLKTED-SLMPEEEFLRRNKGPVSIKVQVPNMQDKTEWKLNGQGLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGI-FIKDSNSLAYYNMASGAVIHLALKERGGRKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3I142-1", "uniprot_id": "G3I142_CRIGR", "id": "G3I142-1", "name": "Splicing factor 3A subunit 1", "aln": "----MPAGPVQAVPPP------PPVATEPKQPVEEEASSKEESTPSKP---------VVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGK--------AQEPSAAIPKVMQQQQQATQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFAKLKKEAENPR----EVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDEKQEKAEEAP----SQLD---------------------QDTQVQDMDEGSDDDEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDR---SIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGV--EETAIGKKIGEEE-IQKPEEKVTWDGHSGSMARTQ-QAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKP-NEIPQQPPPPSSATNIPSSAPPITSVPRPPAMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIA-PMPPIIHAPRINVVPMPPA--APPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPPSKKLKTED-SLMPEEEFLRRNKGPVSIKVQVPNMQDKTEWKLNGQGLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGI-FIKDSNSLAYYNMASGAVIHLALKERGGRKK", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "A0A287ACP7-1", "uniprot_id": "A0A287ACP7_PIG", "id": "A0A287ACP7-1", "name": "", "aln": "----MPAGPVQAVPPP------PPAATEPKQPTEEEASSKEDSTPSKP---------VVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGK--------AQEPSAAIPKVMQQQQQATQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFTKLKKEAENPR----EVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDDEDEKQDKAEEPP----SQLD---------------------QDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDR---SIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGV--EETAIGKKIGEEE-IQKPEEKVTWDGHSGSMARTQ-QAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKP-NEIPQQPPPPSSATNIPSSAPPITSVPRPPAMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIA-PMPPIIHAPRINVVPMPPS--APPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPASKKLKTED-SLMPEEEFLRRNK--VCDPVVLP---------------------------------------------------------------MAWPGVPRLGLG-------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A2VDN6-1", "uniprot_id": "SF3A1_BOVIN", "id": "A2VDN6-1", "name": "Splicing factor 3A subunit 1", "aln": "----MPAGPVQAVPPP------PPAATEPKQPTEEEASSKEDSTPSKP---------VVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGK--------AQEPSAAIPKVMQQQQQASQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFTKLKKEAENPR----EVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDEKQEKAEEPP----SQLD---------------------QDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDR---SIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGV--EETAIGKKIGEEE-IQKPEEKVTWDGHSGSMARTQ-QAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKP-NEIPQQPPPPSSATNIPSSAPPITSVPRPPAMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIA-PMPPIIHAPRINVVPMPPS--APPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPASKKLKTED-SLMPEEEFLRRNKGPVSIKVQVPNMQDKTEWKLNGQVLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGI-FIKDSNSLAYYNMANGAVIHLALKERGGRKK", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q15459-1", "uniprot_id": "SF3A1_HUMAN", "id": "Q15459-1", "name": "Splicing factor 3A subunit 1", "aln": "----MPAGPVQAVPPP------PPVPTEPKQPTEEEASSKEDSAPSKP---------VVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGK--------AQEPSAAIPKVMQQQQQTTQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPR----EVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPP----SQLD---------------------QDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDR---SIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGV--EETAIGKKIGEEE-IQKPEEKVTWDGHSGSMARTQ-QAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKP-NEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIA-PMPPIIHAPRINVVPMPPS--APPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTED-SLMPEEEFLRRNKGPVSIKVQVPNMQDKTEWKLNGQVLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGI-FIKDSNSLAYYNMANGAVIHLALKERGGRKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1NU16-1", "uniprot_id": "F1NU16_CHICK", "id": "F1NU16-1", "name": "Splicing factor 3A subunit 1", "aln": "----MPAGPVQAGPPA------QPAPPAESKPPEEEP--KEEAAPAKP---------VVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGK--------AQEPSAAIPKVMQQQQ-TAQQQLPQKVQAQVIQETVVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLLIKLKKEAENPK----EVLDQVYYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDEKQEKTDEPS----TQLD---------------------QDTQVQDMDEGSDDEDESQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDR---SIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGV--EETAIGKKIGEEE-IQKPEEKVTWDGHSGSMARTQ-QAAQANITLQEQIEAIHKAKGLVPEDDSKEKIGPSKP-NEMPQ-PPPPSSASNPPPSAQPITSVPRPPTMPPPVRAAVVSAVPVMPRPPMTSVVRLPPGSVIATPMPPIIHTPRINVVPMPPS--APPIMSPRPPPMIVPTAFVPAPPVAPVPSPAPMPPVHPPPPMEDEPVSKKLKSED-SLIPEEEFLRRNKGPVTVKVQVPNMQDKTEWKLNGQVLVFTLPLSDQVSVIKVKIHEATGMPAGKQKLQYEGI-FIKDSNSLAYYNMTSGSLIHLALKERGGRKK", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9VEP9-1", "uniprot_id": "Q9VEP9_DROME", "id": "Q9VEP9-1", "name": "Splicing factor 3A subunit 1", "aln": "------------------------MATLDAEANEEQFGNDQPKSMSGP---------IIGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNELGNPKFNFLNGGDPYHAYYRHKVNEFREGN--------DAG-ITALASMKQLAVTSAAQQRQQELLKQVVEQQFVPKEPPPEFEFIADPPSISALDLDIVKLTAQFVARNGRQFLTNLMSREQRNFQFDFLRPQHSLFQYFTKLLEQYTKVLIPPKDLLGKLRSESAPGRSSMNQVLEQVKYRANWQRHQEAQRRREEEKIERERVAYAQIDWHDFVVVETVDYQPFESGNFPPPTNPDEVGARVLMEER--LMDEEGDTEMQIESDDEGDSQANNLLDSGLKLSQMENRVGIQMKNVSSYGQPTGPKRDNTQVQDMDEASSDEDTPTTKLQPSVAPM---LPPTHDKVVVKK-YDPKATQPKQAPMPTDEYLISPITGEKIPASKVSEHMRIGLLDPRWVEQRDK---HTVEKINQDNVFAAGTAIEASLKQLAERRTDIFGVGDEETVIGKKLGEEE-TKK-DDRVTWDGHTSSVEAAT-RAARANITLEEQIHQIHKVKGLLP-DEEKEKIGPKPVGNKATLSAPPQPSTKSQHSHSSQSQHHQGGGGGHHGHHNPHHHHPPHQQAPPHQSHHHHPPQQPQP-VMQLMQLRPTMMQPPFGAG--GGGYMNMQPG--GIPQQIAPAPPVD---------------IMEEEPPSKKIRSED-NLIPEADFIATHKSPVTIQVLVPN-SDKSEWKLNGQMIAVTMALSEPIANLKTKLQDETGMPPAKQKIFYEGM-FFKDSNTMAFYNLVNGTTVHLQVKERGGRKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8RXF1-1", "uniprot_id": "SF3A1_ARATH", "id": "Q8RXF1-1", "name": "Probable splicing factor 3A subunit 1", "aln": "MFSSMQILPLEAPPTDGKLGPLPPSQLTDQEVEERELQAEQNNSNLAPPAAVATHTRTIGIIHPPPDIRTIVEKTAQFVSKNGLEFEKRIIVSNEKNAKFNFLKSSDPYHAFYQHKLTEYRAQNKDGAQGTDDSDGTTDPQLDTGAADESEAGDTQPDLQAQFRIPSKPLEAPEPEKYTVRLPEGITGEELDIIKLTAQFVARNGKSFLTGLSNRENNNPQFHFMKPTHSMFTFFTSLVDAYSEVLMPPKDLKEKLRKSAADLT----TVLERCLHRLEWDRSQEQQKKKEEDEKELERVQMAMIDWHDFVVVESIDFADEEDEELPPPMTLDEVIRRSKASAMEEDEIVEPGKEVEMEMDEEE---------------------------------------VKLVAEGMRAANLEENVKIENVHDEEAPMR----------IVKNWKRPEDR--IPTERDPTKVVISPITGELIPINEMSEHMRISLIDPKFKEQKDR---MFAKIR--ETTLAQDDEIAKNIVGLARLRPDIFGTTEEEVSNAVKAEIEKKKDEQPKQVIWDGHTGSIGRTANQALSQNANGEEQGDGVYGDPNSFPGPAALPPPRPGVP--IVRPLPPPPNLALNLPRPPPSAQYPGAPRPLGVPMMQPMHQQHQLTMPG--------PPGHPQMMMNRPPQMQPGMHVPPPPGSQFAHHMQIPRPYGQLPPSAMGMMQPPPMPGMAPPPPPEEAPPPLPEEPEAKRQKFDESALVPEDQFLAQHPGPATIRVSKPNENDGQFMEITVQS------LSENVGSLKEKIAGEIQIPANKQKLSGKAG-FLKDNMSLAHYNVGAGEILTLSLRERGGRKR", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q86A14-1", "uniprot_id": "SF3A1_DICDI", "id": "Q86A14-1", "name": "Probable splicing factor 3A subunit 1", "aln": "-MANEIITPTEGELKTIIDKTAAYAAKLGESFENKVKQREGHNAKFN--------FMKEGDQYYPYYRNKIVENKAKIQADAAAAAAAANPKTPSTTTTTTTTTTATTPLPTATATTTSPTPTTSSTIVP-VPQTNSTQQLQQQQQQQQQTTPVFEKPQPPPPPPPKKEPTQPDPLLYILDVPDFMTPLELDTIRLTAQFIAKNGDSFFMELASREVKNSQFDFLKPTNHLYEWFRALVESYAQIIYPPQGIKEQLKSNYFSNK---QTILERAMNRCEYNQLKEIEEQKKEEREDEEKTIIASIDWHDFVIVDTIEFNEDDLDDLPQPRTFDQLIAGDTPFGGSDFDNDGHGSNGKGGQDMEME--------------------------------------MDMEMEMDDEDNNNNEDEIEESSLSSTNTTGNLPPKDQSKLKIVKDYQKSNSSVKSNAPTKLTQLCQFCKQEIPLDEMQEHMRIELIQKQQRDSRLGGGGSSNNNNNLTNTLTQDDDIARNLQSFASKRVDIFGE----TESSKKQDEQP---TQAPKVIWDGHSGSIPRVQ--AAQQAAQLAAQQAAQQKAAAIAAQQASQQQASQQQQ----QQLQPPQPIGIHHHPQRHLPPGMMPPGMMPPGMMPPGMMPPGMVPPPPFG---MIPPGMVPP-------PPPGLMIPTAPPG-----LMIPPTQQQQLPPQTNTSPSSS-------------SSIKVEEPQSKKLKIDD-VLIPESVWLQNNPNPVNLTVEMADKSNIYQITLQP---------TDSISLLKEKIKELNGMPTNKQKLQAPGLSILKDTCSIAFYNLKSLAIVTCGQKKKGGKKK", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. . : * : * ..**::.*.: : . . ... . . . . . .. . : * * : * :: :** ::*****:*:** .*: * .:* .* **.*::* : :: :* *:: *:::: **:.: :*:.. :*:: * :: : :* :.:::*:. : *:. * *******:*::::: : ::* * . ::: : : * * . : . ::: : : : . . :. : : ** .::.***** *:: : :.: : . : . * .: :* * **** . . * : :* ****:.*: . * * . ** . ** * : . . . * . :** :*: : :: *:** :: : . * . : ", "identical_positions": 87, "similar_positions": 153, "identity": "10.09%" }, { "cls_id": "homologset.oma.814802", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FWT7-1", "uniprot_id": "UBCP1_RAT", "id": "Q5FWT7-1", "name": "Ubiquitin-like domain-containing CTD phosphatase 1", "aln": "----------------------------------------------------------------------------MSLPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVKLGALKLKPNTKIMMMGTREESL-EDVLCPPPDNDDVINDFDIEDEVVE--VENREENLLKISRRVKEYK-VEVLNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTP--------RRGLIDVKPLGVIWG--KFSEFYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKELVKLTQYLKEIAK-LDDFLELNHKYWERYLS---KKQGQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGR9-1", "uniprot_id": "UBCP1_MOUSE", "id": "Q8BGR9-1", "name": "Ubiquitin-like domain-containing CTD phosphatase 1", "aln": "----------------------------------------------------------------------------MALPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVKLGALKLKPNTKIMMMGTREESL-EDVLCPPPDNDDVINDFDIEDEVVE--VENREENLLKVSRRVKEYK-VEVLNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTP--------RRGLIDVKPLGVIWG--KFSEFYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKELVKLTQYLKEIAK-LDDFLELNHKYWERYLS---KKQGQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WVY7-1", "uniprot_id": "UBCP1_HUMAN", "id": "Q8WVY7-1", "name": "Ubiquitin-like domain-containing CTD phosphatase 1", "aln": "----------------------------------------------------------------------------MALPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVKLGALKLKPNTKIMMMGTREESL-EDVLGPPPDNDDVVNDFDIEDEVVE--VENREENLLKISRRVKEYK-VEILNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTP--------RRGLIDVKPLGVIWG--KFSEFYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKELLKLTQYLKEIAK-LDDFLDLNHKYWERYLS---KKQGQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2KJD7-1", "uniprot_id": "UBCP1_BOVIN", "id": "Q2KJD7-1", "name": "Ubiquitin-like domain-containing CTD phosphatase 1", "aln": "----------------------------------------------------------------------------MALPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVKLGALKLKPNTKIMMMGTREESL-EDVLGPPPDNDDVVNDFDIEDEVVE--VENREENLLKISRRVKEYK-VEILNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTP--------RRGLIDVKPLGVIWG--KFSEFYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKELLKLTQYLKEIAK-LDDFLDLNHKYWERYLS---KKQGQ-", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A5G2QQI4-1", "uniprot_id": "A0A5G2QQI4_PIG", "id": "A0A5G2QQI4-1", "name": "Ubiquitin-like domain-containing CTD phosphatase 1", "aln": "----------------------------------------------------------------------------MALPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVKLGALKLKPNTKIMMMGTREESL-EDVLGPPPDNDDVVNDFDIEDEVVE--VENREENLLKISRRVKEYK-VEILNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTP--------RRGLIDVKPLGVIWG--KFSEFYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKELLKLTQYLKEIAK-LDDFLDLNHKYWER------------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q5ZJJ8-1", "uniprot_id": "UBCP1_CHICK", "id": "Q5ZJJ8-1", "name": "Ubiquitin-like domain-containing CTD phosphatase 1", "aln": "----------------------------------------------------------------------------MSLSLIIKWGGQEYTITSLSEEDTVLDLKQSLKGLTGVLPERQKLLGLKMKGKPADDDVKLGALKLKPNTKIMMMGTREESL-EDVLGPPPDNDDVINDFDIEEEVVE--VENREENLLKISRRVKEYK-VEILNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTP--------RRGLIDVKPLGVIWG--KFSEYYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKELLKLTQYLKEIAK-LDDFLELNHKHWERYLS---KKQGQ-", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q6DI37-1", "uniprot_id": "UBCP1_DANRE", "id": "Q6DI37-1", "name": "Ubiquitin-like domain-containing CTD phosphatase 1", "aln": "----------------------------------------------------------------------------MSVSVIIKWGGQEYSINTLSEEDTVLDLKQSIKSLTGVLPERQKLLGLKLKGKPADDNVKLGDLKLKPNTKIMMMGTREESL-EDVLAPPPENDDVVNDFDIEEEVTE--VENREENLAKIARRVKDYK-VEELNPPRPGKRLLVLDIDYTLFDHKSCAETGHELMRPFLHEFLTSAYEDFDIVIWSATSMKWIDAKMKELGVTDNPNYKITFMLDSAAMITVHTP--------KRGVVEVKPLGVIWG--KYSEFYNRKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNREKDKELYKLSQYLKEIAK-LDDFSGLNHKHWERYLS---KKQNQ-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XZ16-1", "uniprot_id": "UBCP1_DROME", "id": "Q9XZ16-1", "name": "Ubiquitin-like domain-containing CTD phosphatase 1", "aln": "-------------------------------------------------------------------------MEVKEVVVIVKWSGKEYPVD-LTDQDTVEVLRHEIFRKTQVRPERQKLLNLKYKGKTAADNVKISALELKPNFKLMMVGSTEADI-EDACSLPDNIGEVVDDFDDADEREES-VEHSAVYLAKVQRRVRDYK-IKELAPPREGKKLLVLDIDYTLFDHRSPAETGTELMRPYLHEFLTSAYEDYDIVIWSATSMRWIEEKMRLLGVASNDNYKVMFYLDSTAMISVHVP--------ERGVVDVKPLGVIWA--LYKQYNS-SNTIMFDDIRRNFLMNPKSGLKIRPFRQAHLNRGTDTELLKLSDYLRKIAHHCPDFNSLNHRKWEHYHP---KKNS--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8W3M6-1", "uniprot_id": "UBCP_ARATH", "id": "Q8W3M6-1", "name": "Ubiquitin-like domain-containing CTD phosphatase", "aln": "-------------------------------------------------------MASSSSSPTPSAAAAVSPLTEEELTLTVKWNGKEYTVR-ICADDSVAELKRRICLLTTVLPKRQKLLYPKIGNKLSDDSLLLSSISFKPSLKMTMIGTVED----DIIVDQAESPEIVDDFELGKEEAVD-VKDKEVNKQKLRRRIDQYK-INLRTPCRQGKKLLVLDIDYTLFDHRSTAENPLQLMRPYLHEFLTAAYAEYDIMIWSATSMKWVELKMTELGVLNNPNYKVTALLDHLAMITVQSD--------TRGIFDCKPLGLIWA--LLPEFYNPGNTIMFDDLRRNFVMNPQNGLTIKPFRKAHANRDTDQELVKLTQYLLTIAE-LSDLSSLHHSRWESFSQDNVKRRRQE", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q556S4-1", "uniprot_id": "Q556S4_DICDI", "id": "Q556S4-1", "name": "protein-serine/threonine phosphatase", "aln": "MDTIVSSSTTNPPTTTESTINSIITTTDSNSNNTNDNTTTNTTTTTTTTTTTNIINDSDLKTKTTTTTTTIINEENSKITIKTKWNGKEYKVL-ISKSSTVFDLKRQLETMTNVLSKRQKILGLS-KGKQPTDEMIIESLSIQDNHSIIMMGTPESNIIADVPKTSGDTDEVFNDFEFDYIPDSDEISHIEKNKNQLLAMIERSNDISLINDPRPNKKLLVLDLDHTILDFK--DQDVENMKRPHLEEFLVQSYQHYDIGIWSQTSWKWIEIKLTELGLLTNPRFKICFVMDQTLMFKVTTYRTINGKERTKIKHNVKALEVIWKHQHLGKFFSMKNTLHVDDLSKNFAMNPKNGVHVPPFKIKDAKKYGDNVLFHLTKYLKSISN-EEDITLIDHKEWIRKIL---------", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : **.*:** : : ..:* *:: : * * .:***:* . .* . :.: : :.:: . .: *:*: * * : ::.:**: :.. :: : : :. * .*:*****:*:*::*.: : :: **.*.***. :* .:** *** *. :*:: *: **: * .:*: :* *:.* : : *.* :** :: . **: .**: :** ***:.*: : ** . :: * * :*:.** *:. *: :.* * ", "identical_positions": 77, "similar_positions": 101, "identity": "18.64%" }, { "cls_id": "homologset.oma.814807", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JT90-1", "uniprot_id": "A0A0G2JT90_RAT", "id": "A0A0G2JT90-1", "name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "aln": "MAATGVGPGPGVGAGSGPGAAASATTTEDRETEPATAG----AGEGPSAAPGAEPSSGEAESGDANLVDVSG-LETESSNGKDTLEGAGDTSEVMDTQAGSVDEENGRQLGEVELQCGICTKWF--TADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERD-VFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSASGNLNGGATLGGGIAAGSSGKGRGAKRKQQ---DGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDC-WAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPSFKYPPKDVTYHP--MSDMGWGAVVEHTLADVLYHVETEVDGRRSPPWEP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91X20-1", "uniprot_id": "ASH2L_MOUSE", "id": "Q91X20-1", "name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "aln": "MAAAGAGPGPGVSAGPGPGAAASATTAEDRETEPVAAG----AGEGPSAAPGAEPSSGEAESGDANLVDVSG-LETESSNGKDTLEGTGDTSEVMDTQAGSVDEENGRQLGEVELQCGICTKWF--TADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERD-VFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSASGNLNG------GIAAGSSGKGRGAKRKQQ---DGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDC-WAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEIIFYKNGVNQGVAYRDIFEGVYFPAISLYKSCTVSINFGPSFKYPPKDLTYHP--MSDMGWGAVVEHTLADVLYHVETEVDGRRSPPWEP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBL3-1", "uniprot_id": "ASH2L_HUMAN", "id": "Q9UBL3-1", "name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "aln": "MAAAGAGPGQEAGAGPGPGAVANATGAEEGEMKPVAAGAAAPPGEGISAAPTVEPSSGEAEGGEANLVDVSGGLETESSNGKDTLEGAGDTSEVMDTQAGSVDEENGRQLGEVELQCGICTKWF--TADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERD-VFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSTSGNLNG------GIAAGSSGKGRGAKRKQQ---DGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDC-WAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPCFKYPPKDLTYRP--MSDMGWGAVVEHTLADVLYHVETEVDGRRSPPWEP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0Z4L1-1", "uniprot_id": "A0A8V0Z4L1_CHICK", "id": "A0A8V0Z4L1-1", "name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "aln": "MAAAAAA----AAAMAAPAGESAEAAPEPPAAEPPAPP-------EPSAADAE--SGGEAAPGDA----AAAAVETETASGKDPMEAAPDGPEAMDTQAGSVDEENGRQLGEIELQCGICTKWF--TADTFGIDTTSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMCKERD-VFLVKEHPDPGSKDPEEDYPKFGLLDQDLANIGPAYDNQKQNNAVSTSGNLNDGASLGGGIAAGGSGKGRGAKRKQQ---DGSTTGTAKKTRSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDC-WAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEISMDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYISLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQAPGSQIIFFKNGASQGVAFKDIFEGVYFPAISLYKGCTVSINFGPYFKYPPRDITYRP--MSDMGWGAVVEHTLADVLYHVETEVDGRRSPPWEP-", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "F1RAW8-1", "uniprot_id": "F1RAW8_DANRE", "id": "F1RAW8-1", "name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "aln": "-----------------------------------------------MAAEARSVTERDTADGDASFGDLTTNMETESSSGKETMDTAGDSSEAADAQTGSGDDENGRQLGEVELQCALCMKWF--TADTFSIDTATCLPFMTNYVFHCNVCHHSGNTYFLRKQANLKEMCLTALANLTWRSRTQEEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKLTWPNNIVKTMSKERD-VFLVKEHPDPGSKDPEEDYPKFGLLDQDLGNIGPSYDNQKQMTTVTGAGGLNGGSTFSGGLPSAATGKGRGAKRKQQQQQDGAATGAAKRTRSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDC-WAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVTGEKGYSMVRASHGVRKGSWFFEVTVDEMPQDAAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTRFHQSIGKHYSDGYGLGDILGFFIELPDETETAKALPDTYKDKALIKFKSYLYFEEKDYVDKAEKNLKPTSTSRMIFFKNGVNQGVAYEDLFEGMYYPAISLYKGCTVSVNFGPHFKYPPKDIKFQP--MSDMGWGAVIEHTLADMLYHVETEVDGRRSPQYEG-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94545-1", "uniprot_id": "ASH2_DROME", "id": "Q94545-1", "name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "aln": "----------------------------------------------------MEDSQMDTS------------SPTESSSEVN-FTAEEDKSQETRSAAGVCYCGKERNLNIVELLCATCSRWVHETCVSYQLGKGKLLPFITNYVFVCKNCSASGLESFRKSQATISQMCHCAIANMQ-QAASRDGRRQIQFSKDKEIIPYIEQYWEAMTTMPRRLTQSWYSTVQRSLVKDVQTLFTYEEHAEHG--------AMYGLFHQDLRIIKPNYESMSKSGALRLTD---------DGYTQASLSKNNRQKRKFPG-TDSGPTGKKGRPSSD-ITANVKLPPHGYPLEHPFNKDGYRYILAEPDPHAPFRQEFDESSDWAGKPIPGWLYRILVPHSVLLALHDRAPQLKISEDRLAVTGERGYCMVRATHSVNRGCWYFEVTIEEMPDGAATRLGWGREYGNLQAPLGYDKFGYSWRSRKGTKFTESHGKHYSDAYVEGDTLGFLIELPEEAS-LDYLPNTFKDRPLVKFKSHLYYEDKDKITETLKNLHILQGSRIEFFKNGQSQGVAFEDIYAGSYFPAISIHKSATVSVNFGPAFKYPEVLVEHKAKGMHDRVEELITEQCLADTLY--LTEHDGRLRLDNMGL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: **::. : : * .: : :* : *:*. :** *. * :*. *. :: :.. . ***:*** * *: * ** * :.**.:.:** *:**: :: ::: : : *****:***:*::***.*** * . :* ..: ::: *: : :* :**.: * . :**:.*** * * *:. .: :: :. * . .. .*.. *** *...** :. ** : : :***************************** :::: .. ******** *** : . ***************:***:*.**:**.****:*.*.:*.*:**::::*** .:*:****.: ************.*****:***:* :* *****..* ** *** *.**:::. . **:*:**:.*:****:**:*:** : :: *.*: *.: *:*** .****:.*:: * *:****::*..***:**** **** : .:. * * : *: *** ** ** *** ", "identical_positions": 246, "similar_positions": 161, "identity": "38.2%" }, { "cls_id": "homologset.oma.814852", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZPB8-1", "uniprot_id": "D3ZPB8_RAT", "id": "D3ZPB8-1", "name": "", "aln": "---------------------------------------------------------------------------------------MASAELDYSIEIPDQPCWSQKN--SQGGKEAGKQQPVVILLGWGGCRDKNLAKYSAIYHKRGCIVIRYTAPWHMVFFSES--LGIPSLRVVAQKLLELLFDYEIEREP--LLFHVFSNAGVMLYRYVLELLQTHQRFRHLHVVGTIFDSGPGD--SDLIGALRALATILE---------RRP-AVLRLLLLAAFALVVVLFHFLFAPFTALFHT------------HFYDRLQDSGSCWPELYLYSRADKVVSARDVERMVEERLAHQVSVRGVDFVTSAHVSHLRDYPTYYTSLCVDFMHNCVQC-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0Z3-1", "uniprot_id": "TMM53_MOUSE", "id": "Q9D0Z3-1", "name": "Transmembrane protein 53", "aln": "---------------------------------------------------------------------------------------MASAELDYSIEIPDQPCWSQKN--RQGGKEAGKQQPVVILLGWGGCRDKNLAKYSAIYHKRGCIVIRYTAPWHMVFFSES--LGIPSLRVIAQKLLELLFDYEIEREP--LLFHVFSNAGVMLYRYVLELLQTHQRFRHLHVVGTIFDSGPGD--SNLIGALRALATILE---------RRP-AVLRLLLLAAFALVVILFHFLLAPFTALFHT------------HFYDRLQDSGSCWPELYLYSRADKVVSARDVERMVEARLAHQVMVRGVDFVSSAHVSHLRDYPTYYTSLCVDFMHNCVQC-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A061IDL9-1", "uniprot_id": "A0A061IDL9_CRIGR", "id": "A0A061IDL9-1", "name": "", "aln": "---------------------------------------------------------------------------------------MASAELDYSIEIPDQPCWSQKNP-CHDGKKARKRLPVVILLGWGGCRDKNLAKYSAIYHKRGCIVIRYTAPWHMVFFSES--LGIPSLRVMAQKLLELLFDYEIEREP--LLFHVFSNGGVMLYRYVLELLQTHQRFRHLHVVGTVFDSGPGD--SNLVGALRALAIILE---------RRP-TVLRLLLLVAFALVVVLLHFLLSPFTALFHT------------HFYDRLQDSGSHWPELYLYSRADEVVSARDVERMVEERLAHQVLVRSVDFVSSAHVSHLRDYPTYYTSLCVDFMQNCVQC-----------------------", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q6P2H8-1", "uniprot_id": "TMM53_HUMAN", "id": "Q6P2H8-1", "name": "Transmembrane protein 53", "aln": "---------------------------------------------------------------------------------------MASAELDYTIEIPDQPCWSQKNSPSPGGKEAETRQPVVILLGWGGCKDKNLAKYSAIYHKRGCIVIRYTAPWHMVFFSES--LGIPSLRVLAQKLLELLFDYEIEKEP--LLFHVFSNGGVMLYRYVLELLQT-RRFCRLRVVGTIFDSAPGD--SNLVGALRALAAILE---------RRA-AMLRLLLLVAFALVVVLFHVLLAPITALFHT------------HFYDRLQDAGSRWPELYLYSRADEVVLARDIERMVEARLARRVLARSVDFVSSAHVSHLRDYPTYYTSLCVDFMRNCVRC-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A4X1W9T2-1", "uniprot_id": "A0A4X1W9T2_PIG", "id": "A0A4X1W9T2-1", "name": "", "aln": "---------------------------------------------------------------------------------------MASAQLDYTIEIPDQSCRSQEDSPNQGGKEAGTRQPLVILLGWGGCTDKNLAKYSAIYHKRGCIVIRYTAPWHMVFFSES--LGIPSLRVLAQKLLELLFDYEVEKEP--LLFHVFSNAGVMLYRHVLELLQTQRRFCHLRVVGTIFDSGPGD--SNLLGALRALAAVLG---------HRP-AALRLLLLAAFALVAVLVHGLLAPLTALFHT------------HFYDRLLNAASRWPELYLYSRADEVVLARDVERMVEARLAHRVLVRSVDFVSSAHVSHLRDYPTYYTSLCVNFMRSCVHG-----------------------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q6DHN0-1", "uniprot_id": "TMM53_DANRE", "id": "Q6DHN0-1", "name": "Transmembrane protein 53", "aln": "---------------------------------------------------------------------------------------MGDDDLDYNIVFS-EALISEKH-------WRGSKEPVVILLGWAGSRDKHLAKYSSIYNEQGCTTLRYTAPLKTVFISES--LGYKELRSTAHKLLELLYDYEVENNP--IFFHVFSNGGFMLYRYMVELLHSHKQFSTLCVVGTVVDSAPGS--QNVVGALRALKTTLG---------PKVNVLLQYFLLALFAVAVFLLRIVLYPLTKYFHR------------NHYDAMMEHPAPWPQMYLYSRADRVIRYRDVEKMVKGLQEKGLMVESFDFITPAHVSLFRDCPEDYSNRCRTFLSHCMTTSEEILMKKHH-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z6G9-1", "uniprot_id": "A1Z6G9_DROME", "id": "A1Z6G9-1", "name": "Transmembrane protein 53", "aln": "----------------------------------------------MSISASHPCGLNADGTATQYKESTATIQTSGLQSSPRSFLPEREDTLEYFIKFP-KPSSKNEFVLAKDHDGEDSHVPIVMLLGWAGCQDRYLMKYSKIYEERGLITVRYTAPVDSLFWKRS--EMIP----IGEKILKLIQDMNFDAHP--LIFHIFSNGGAYLYQHIN--LAVIKHKSPLQVRGVIFDSAPGE--RRIISLYRAITAIYGR--------EKRCNCLAALVITITLSIMWFVEESISALKSLFVPSS------PVRPSPFCDLKNEANRYPQLFLYSKGDIVIPYRDVEKFIRLRRDQGIQVSSVCFEDAEHVKIYTKYPKQYVQCVCNFIRNCMTIPPLKEAVNSEPSESVSRVNLKYD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8S8G6-1", "uniprot_id": "Q8S8G6_ARATH", "id": "Q8S8G6-1", "name": "", "aln": "MEATTRILSTSSALNRLLLLSKLNLKSDPRNINSTNQLLHNAVTRKSSISAARIRCSSLPANANLFRSLFFLTSTFRLENTAVHANPFRSEPNDGVAVWNRAPRIVNGGGNAAIFGGNEGKETTVVLLGWLGAKAKHLRRYVEWYNSRGINAVTFTVDVRDLLRLDLGRRLERRIAEFGNELVNWVSEKEDDGREKCLVFHSFSNTGWLVYGALLESFIGRQDLVER-IKGCIIDSGGADPLDTKIWAAGFTAAILKKRSSTITTEPNSPIKEEDASTPQKKEPLGIENIMLSSLEKLFPIFLNHPDVNTRLTKIIQKLYENHPPCPQLYLYSSGDKVVPSHSVELRIREQQKIGRKIHSFNFKSSPHVDHYRNFPDLYSSQLQNFLQECFTPTKQQAL-----------------", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : : . *:**** *. : * :* *..:* .: :*. :: ..:::: : : : : . :.** *** * :* : : : : * :.**. .. : . : . : .: * : : *:::*** .* *: :.:* :. .. * . **. . * * . *: *. ", "identical_positions": 36, "similar_positions": 69, "identity": "8.65%" }, { "cls_id": "homologset.oma.814927", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q08326-1", "uniprot_id": "MSS4_RAT", "id": "Q08326-1", "name": "Guanine nucleotide exchange factor MSS4", "aln": "-------MEPCELQNE--------------LVSAEGRNRKAVLCQRCGSRVLQPGTALFSRRQLFLPSMRKKPDLVDGSNPDGDVLEEHWLVNDMFIFENVGFTKDVGNVKFLVCADCEIGPIGWHCLDDKNSFYVALERVSHE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91X96-1", "uniprot_id": "MSS4_MOUSE", "id": "Q91X96-1", "name": "Guanine nucleotide exchange factor MSS4", "aln": "-------MEPCELQNE--------------LVSAEGRNRKAVLCQRCGSRVLQPGTALFSRRQLFLPSMRKKPDLADGSNPDGDLLQEHWLVNDMFTFENVGFTKDVGNIKFLVCADCEIGPIGWHCLDDKNSFYVALERVSHE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47224-1", "uniprot_id": "MSS4_HUMAN", "id": "P47224-1", "name": "Guanine nucleotide exchange factor MSS4", "aln": "-------MEPAEQPSE--------------LVSAEGRNRKAVLCQRCGSRVLQPGTALFSRRQLFLPSMRKKPALSDGSNPDGDLLQEHWLVEDMFIFENVGFTKDVGNIKFLVCADCEIGPIGWHCLDDKNSFYVALERVSHE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1S4M9-1", "uniprot_id": "F1S4M9_PIG", "id": "F1S4M9-1", "name": "Guanine nucleotide exchange factor MSS4", "aln": "-------MDPITPPSE--------------LVSAEGRNRKAVLCQRCRSRVLQPGTALFSRRQLFLPSMKKKPAPADGGSPEGDLLQEHWLVDDMFIFENVGFTKDVGNVKFLVCADCEVGPIGWHCLDDKNSFYVALERVSHE--", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A8V0ZZX9-1", "uniprot_id": "A0A8V0ZZX9_CHICK", "id": "A0A8V0ZZX9-1", "name": "Guanine nucleotide exchange factor MSS4", "aln": "MAAACAEMEPAAAPPSSPPAPVAASPGSAGLVCAQGRNLKAVLCQRCGSRVLLPGAATFARRELLLPAMRKKATADGDGDGDGDVLQEHWLVRDMFSFENVGFTRDVGNVKFLVCADCEAGPIGWHCLDDKDSFYVALERVAHE--", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9VLP3-1", "uniprot_id": "MSS4_DROME", "id": "Q9VLP3-1", "name": "Guanine nucleotide exchange factor MSS4 homolog", "aln": "-------MTEEADFSE---------------QITDGKNKSNVRCQFCNCLMLKAQEGTYNQEEVDVPLMTQKQDRTADS-LNSEPLKDFWLVKDMMTFENIGFSNTVDGRKFLVCADCERGPVGYHDLSTR-HCYLALKRVVHKDT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . ::*:* . * ** * . :* . . : :.:: :* * :* .. :.: *::.*** **: ***:**:. *.. ********* **:*:* *. : *:**:** *: ", "identical_positions": 43, "similar_positions": 37, "identity": "29.45%" }, { "cls_id": "homologset.oma.814949", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P24668-1", "uniprot_id": "MPRD_MOUSE", "id": "P24668-1", "name": "Cation-dependent mannose-6-phosphate receptor", "aln": "-----------------------------------------------MFPFSGCWRTELLLLLLLAVAVRESWQIE-EKSCDLVGEKDKESKNEVALLERLRPLFNKSFESTVGQGS-DTYSYIFRVCREASNHSSG-AGLVQINKSNDKETVVGRINETHIFNGSNWIMLIYKGGDEYDNHCGKEQRRAVVMISCNRHTLAANFNPVSEERGKVQDCFYLFEMDSSLACSPEVSHLSVGSILLVIFASLVAVYIIGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVA----------------DGCDFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AY20-1", "uniprot_id": "MPRD_RAT", "id": "Q6AY20-1", "name": "Cation-dependent mannose-6-phosphate receptor", "aln": "-----------------------------------------------MFPLSGCWRTELLLLLLLAVAVRESWQIE-EKSCDLVGEKDKESKNEVALLERLRPLFNKSFESTVGQGS-DTYSYIFRVCREAGNHSSG-AGLVQINKSNEKETVVGRINETHIFNGSNWIMLIYKGGDEYDNHCGKEQRRAVVMISCNRHTLAGNFNPVSEERGKIQDCFYLFEMDSSLACSPEVSHLSVGSILLVIFASLVAVYIIGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVA----------------DGCDFVCRSKPRSVPAAYRGVGDDQLGEESEERDDHLLPM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8C2MCD2-1", "uniprot_id": "A0A8C2MCD2_CRIGR", "id": "A0A8C2MCD2-1", "name": "Cation-dependent mannose-6-phosphate receptor", "aln": "-----------------------------------------------MFPFSGCWRTELLLLLVLALAVRESWQAE-EKSCDLVGDNDKESKQEKALLERLRPLFNKSFESTVGQGL-DTYSYRFRVCREAGNHSSG-AGLVQISKNNGKETVVGRINETHIFNGSNWIMLIYKGGDEYDNHCGREQRRAVVMISCNRRTLAGNFNPVSEERNKVQDCLYLFEMDSSVACSPEVSHLSVGSILLVIFVSLVAVYIIGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVA----------------DGCDFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "P20645-1", "uniprot_id": "MPRD_HUMAN", "id": "P20645-1", "name": "Cation-dependent mannose-6-phosphate receptor", "aln": "-----------------------------------------------MFPFYSCWRTGL-LLLLLAVAVRESWQTE-EKTCDLVGEKGKESEKELALVKRLKPLFNKSFESTVGQGS-DTYIYIFRVCREAGNHTSG-AGLVQINKSNGKETVVGRLNETHIFNGSNWIMLIYKGGDEYDNHCGKEQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACSPEISHLSVGSILLVTFASLVAVYVVGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVA----------------DGCDFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A480WYK9-1", "uniprot_id": "A0A480WYK9_PIG", "id": "A0A480WYK9-1", "name": "Cation-dependent mannose-6-phosphate receptor", "aln": "-----------------------------------------------MVPVDSSWRTGLPLLLLLAVAVRGSWQAE-EKTCDLVGEKGKESEKELALLKRLKPLFNKSFESTVGQGS-DTYMYMFRVCREAGNHSSG-AGLVQINKSNGKETVVGRLNETHVFNGSNWIMLIYKGGDEYDNHCGKEQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACSPEISHLSVGSILLVTFASLVAVYIIGGFLYQRLVVGAKGIEQFPHLAFWQDLGNLVA----------------DGCDFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "P11456-1", "uniprot_id": "MPRD_BOVIN", "id": "P11456-1", "name": "Cation-dependent mannose-6-phosphate receptor", "aln": "----------------------------------------------MMSPLHSSWRTGLLLLLLFSVAVRESWQTE-EKTCDLVGEKGKESEKELALLKRLTPLFNKSFESTVGQSP-DMYSYVFRVCREAGNHSSG-AGLVQINKSNGKETVVGRFNETQIFNGSNWIMLIYKGGDEYDNHCGREQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACSPEISHLSVGSILLVTLASLVAVYIIGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVA----------------DGCDFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A8V0ZSC0-1", "uniprot_id": "A0A8V0ZSC0_CHICK", "id": "A0A8V0ZSC0-1", "name": "Cation-dependent mannose-6-phosphate receptor", "aln": "MGRARVVRQPWLLLWPLGSAPARRLRPVPEQPSFLRRAAVRAERTVHSSRMSSHCHTSAVLVVFMALAAGVGAEPLSEKSCDVVGDESTESQMEKALLKKLEPLSQIRFNTTVEIGTTENYAYHFRVCREVNSSLHDFAGLVQMDRQSGKTTVIGRINETQVFNGSDWIMLIYKGGDSYGRHCSGEKRRAVIMISCKRGITASSFSIISEEREKEQDCFYLFEMDSSVACPAEDSHLSTGSILLITFSALVTVYIVGGFLYQRLIVGAKGMEQFPHFAFWQDLGNLVATVSWIDLPQCTLWEKKDGCDFVCRSKPRNVPAAYRGVGDDQLGDESEERDDHLLPM", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :* *::.:::*. . : **:**:**::..**: * **:::* ** : *::** . : * * ******... . *****:.:.. * **:**:***::****:**********.*..**. *:****:****:* * .*. :**** * ***:********:**..* ****.*****: : :**:**::********:*****:*****:*********** ************.**************:************", "identical_positions": 169, "similar_positions": 67, "identity": "49.13%" }, { "cls_id": "homologset.oma.814985", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q80W47-1", "uniprot_id": "WIPI2_MOUSE", "id": "Q80W47-1", "name": "WD repeat domain phosphoinositide-interacting protein 2", "aln": "-MNLASQSGEAGAGQLLFANFNQDNT------------------SLAVGSKSGYKFFSLSSVD-KLEQIYECTDTEDVCIVERLFSSSLVAIVS----LKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSASIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLEA----VREK--PPEEPTTWTGY----FGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLTTIQKIPRLLVGASDGYLYMYNLDPQEGGECALMRQHRLDGSMETTSEIVDSASHDCPLATQTYGTAAAKGAYVPSSPTRLGKGQDANLEAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AY57-1", "uniprot_id": "WIPI2_RAT", "id": "Q6AY57-1", "name": "WD repeat domain phosphoinositide-interacting protein 2", "aln": "-MNLASQSGEAGAGQLLFANFNQDNT------------------SLAVGSKSGYKFFSLSSVD-KLEQIYECTDTEDVCIVERLFSSSLVAIVS----LKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLEA----VREK--PPEEPTTWTGY----FGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLTTIQKIPRLLVGASDGYLYMYNLDPQEGGECALMRQHRLDGSMETTSEIVDSASHDCPLVTQTYGTAAAKGAYVPSSPTRLGKGQDANLEAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3GVD7-1", "uniprot_id": "G3GVD7_CRIGR", "id": "G3GVD7-1", "name": "WD repeat domain phosphoinositide-interacting protein 2", "aln": "-MNLASQSGEAGAGQLLFANFNQDNT------------------SLAVGSKSGYKFFSLSSVD-KLEQIYECTDTEDVCIVERLFSSSLVAIVS----LKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLEA----VREK--PPEEPTTWTGY----FGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLTTIQKIPRLLVGASDGYLYMYNLDPQEGGECALMRQHRLDGSMETTSEIVDSASHDCPLVTQTYGTAAAKGAYVPSSPTRLAKGQDANLEAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q9Y4P8-1", "uniprot_id": "WIPI2_HUMAN", "id": "Q9Y4P8-1", "name": "WD repeat domain phosphoinositide-interacting protein 2", "aln": "-MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSSVD-KLEQIYECTDTEDVCIVERLFSSSLVAIVS----LKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLET----VKEK--PPEEPTTWTGY----FGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRL---------AYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5ZHN3-1", "uniprot_id": "WIPI2_CHICK", "id": "Q5ZHN3-1", "name": "WD repeat domain phosphoinositide-interacting protein 2", "aln": "-MNLAGQSGDAGSGHLLFANFNQDNT------------------SLAVGSKSGYKFFSLSSVD-KLEQIYECTDTEDVCIVERLFSSSLVAIVS----LKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLET----VKEK--PQEEPTTWTGY----FGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICALATIQKIPRLLVGAADGYLYMYNLDPQEGGECTLMKQHKLDGSMEPANEILESASHDRPLVAQTYSAAVTKGTYVPSSPTRH---------AYTEDLGAVGGACLEDETNSLRLDEDSEHPPMILRTD", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "A0A8M1P910-1", "uniprot_id": "A0A8M1P910_DANRE", "id": "A0A8M1P910-1", "name": "", "aln": "-MNLASQSGEAGCSQLLFANFNQDNT------------------SLAVGTKSGYKFFSLSSVD-KLEQIYECTDTEDVCIVERLFSSSLVAIVS----LKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPSGLCALSISNDNCYLAYPGSATIGEVQVFDTVNLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMEGLYLSASSNTETVHIFKLET----QREKSVPQEEPTTWTGY----FGKVLMASTTYLPAHVTEMFTQGRAFATVRLPFSGHKNICALAIIQKIPRLLVAAADGYLYLYNLDPQEGGECTLMKQHKLDGSAEPANEILEQTAHDRPLVAQTYSAAVAKG--------------------YSEDQGAVGGAGVEDDMNTLHLDEENEQPPLILETD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PER1-1", "uniprot_id": "M9PER1_DROME", "id": "M9PER1-1", "name": "", "aln": "MMSLLGRT-DVDAG-EVFVNFNQNIT------------------SLAVATSGGYSLYSLGSVDSTLDKIYH-TKSDELFLIERLFESSLVAIVS----QRAPRKLKVCHFKKQSEICNYSYANTILAVKLNRERLIVCLEESLYIHNIQDMKVVHTIRDTPCNPQGLCALSSSSEHCYLAYPGSVTAGEVQIFDAINLHAKTMIPAHDTPLAALAFSPSGTEIATASERGTVIRVFSSQDGSRLFELRRGLKRCVSIVSLSFSTCAEYLVSSSNTETVHIFRLDRSATETAEGHGSKQSSDDWMGYS--FFRFLSKTVTSYLPTQVTDVFSQGRAFASVTLPEAGVRRMCAIATIQKQLRLLIASQDGYLYVYSIPTVEGAECQLIKRHDLRLEDHYAMDIKVDSPQTLGLNSGVSIGGAAGVPPSSASAAGAGTGG-----SGGDGKSAVSVTGGVDKPSSSYASAVKGDDPVGPSSA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q54NA2-1", "uniprot_id": "ATG18_DICDI", "id": "Q54NA2-1", "name": "Autophagy-related protein 18", "aln": "-MNVGGKFNEG----ILFLNFNQDFS------------------CIAVGTPEGYKIFNSDPYT-----LYYSQSNGGAGLVEMLFSTSLVSIVGSGDGNTSQRRLLINNIKNNIPICDLNFVTAILSVKMNRKRIVVIMETKIHIYDINNMKLLET-REIASNPKGLCALSPSNTN-YIVYPASQNNGNILVMDVLTLETVNLIQAHKSQISALALSQDGTLLATASDKGTVIRVFALPYANKSLSFRRGSIPAI-IHSMTFSLDGRYLCVSSDTGTIHIFKIDFSSSNSSSFHQAQPSSSPSGGMMGLNFGGLTSKMSSYLPEVISQVWEPSRDFAHIKIPP-GIPSICALMQNNKTAMVLT--ADSLYMQYNFDESVGGELKLAKEFSLLMEPDLDNDVTAKIL-------------------------------------------------------------------------", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.: .: : :* ****: : .:**.: **.::. .. :* .. ::* **.:***:**. : *:* : ::*: **: .: .:**:**:**:*::* :* .::*::*.:**::.* *: . ** ****** .. : *:.**.* . *:: ::*.:.*.: .:* **.: ::***:. .** :****::*******: ..: :.:*** .: * *::** . :* **:* *:***::: . . .. * * : ::*** ::::: .* ** : :* * :*:: :* :* *. *.: *.* * :.. * . . :: . ", "identical_positions": 107, "similar_positions": 134, "identity": "22.34%" }, { "cls_id": "homologset.oma.814986", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8GYD7-1", "uniprot_id": "AT18C_ARATH", "id": "Q8GYD7-1", "name": "Autophagy-related protein 18c", "aln": "MSSTVSNPQGILQPGSFLLPESESMKKEEAELVSVCWNQDSSCFAAGTSHGFRIYNCEPFKETFRRELKDGGFK--------IVEMLFRSNILALVGGGPNSQYPSSKVLIWDDHQSRCISEFAFRSEIRAVKLRRDRIVVVLEHKIYVYNFM-DLRLLH-------------QIETQANPRGLCCLSHHSNTSVLACPG-LNRGEIRVEHFG-------------LNMVQIINAHDSSIACMTLTLDGLLLATASTKGTLIRIFNTMDGTRLQEVRRGVDRADIYSIALSPNVQWLAVSSDKGTVHIFSLRVRVVGEDSYSTENGALLTQQNYSNSLQGLVSPTIGTNPGSSLSFMRGVLP-KYFSSEWSYAQFHVSEVTQFFAAFGSN-----------------------------NTVAIIGMDGSFYRCSFDPVNGGEMGQLEYIHFMKMDNRP--------------------", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q54SA0-1", "uniprot_id": "Q54SA0_DICDI", "id": "Q54SA0-1", "name": "", "aln": "MN--LAN-----------------CKDKHPNLLFANFNQDYSCFACGTEKGFLIFSCDPFKERFGRVF-DGGVG--------IVEMLFRCNILAIVGGGKKPRYTPNQVMIWDDYQNKCIAKLEFKSEVKAVKLRRDRIVVVLENKVYLYNFS-DLQLVH-------------QLETTNNPKGICAICPGT-VNVLACPG-LKPGYVHVELYD-------------LKQTQIIPAHEGALSQIALNKDGTLLATASEKGTLIRIFDTATGEKVKELRRGTNRAEIYSIAFNNDSTALCVSSDKNTGHIFDLSMAKP---SPKEED----TQQ---------------KNRQSTFSFMGDILPTNYFKSEWSAVQFQIPE-SRSICAFGSTP----------------------------NSINVICASGICYKYTYD-FSKGECKREENPHQFIENEES--------------------", "tax_id": 44689, "tax_name": "Social amoeba" }, { "uniprot_ac": "Q9CR39-1", "uniprot_id": "WIPI3_MOUSE", "id": "Q9CR39-1", "name": "WD repeat domain phosphoinositide-interacting protein 3", "aln": "MNLLPCNPHG-------------------NGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLEGGVG--------HVEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMIKVFTFTHNPHQLH-------------VFETCYNPKGLCVLCPNSNNSLLAFPG-THTGHVQLVDLAST-----------EKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQDASLICVSSDHGTVHIFAA------------ED----------------------PKRNKQSSLASASFLPKYFSSKWSFSKFQVPSGSPCICAFGTEP----------------------------NAVIAICADGSYYKFLFS--PKGECVRDVCAQFLEMTDDKL-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5MNZ6-1", "uniprot_id": "WIPI3_HUMAN", "id": "Q5MNZ6-1", "name": "WD repeat domain phosphoinositide-interacting protein 3", "aln": "MNLLPCNPHG-------------------NGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLEGGVG--------HVEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMIKVFTFTHNPHQLH-------------VFETCYNPKGLCVLCPNSNNSLLAFPG-THTGHVQLVDLAST-----------EKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQDASLICVSSDHGTVHIFAA------------ED----------------------PKRNKQSSLASASFLPKYFSSKWSFSKFQVPSGSPCICAFGTEP----------------------------NAVIAICADGSYYKFLFN--PKGECIRDVYAQFLEMTDDKL-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHJ2-1", "uniprot_id": "Q9VHJ2_DROME", "id": "Q9VHJ2-1", "name": "WD repeat domain phosphoinositide-interacting protein 3", "aln": "MNLTEQNPYG-------------------NGLLYAAFNQDQGCFACATDTGFRVYNCDPLKEKERQYFPEGGLS--------HVEMLFRCNYLALVGGGIRPLYPPNKVIVWDDLKKSPAISLDFNQPVRAVRLRRDRIVVVLEGVIKVFTFTQQPQQLH-------------VFETSSNPNGLCVLCPHSNKSLLAFPG-RRTGHVQIVDLANT-----------ERAPLEVIAHEAGISCIALNLQGTRLATAGEKGTLIRIFDTESGKKVSELRRGSNHANIFCINFNHQSTMVVVASDHGTIHVFNL------------ED----------------------NKP-RESSLP---IIPKYFSSQWSFVKFSIPQGPRCVCAFGADP----------------------------NSVVAICADGHYYKFLFN--NKGECSRDICTQFLELQDDET-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50079-1", "uniprot_id": "HSV2_YEAST", "id": "P50079-1", "name": "SVP1-like protein 2", "aln": "MDVRRPIREAVN-------------NRRKPKFLSVSFNQDDSCFSVALENGFRIFNTDPLTSKLSKTFKESATNQSRGTGIGYTRMLYRTNYIALVGGGKRPRHALNKLIIWDDLLQKETITLKFMSSIKDVFLSRIHIVVVLENTIEIFQFQTNPQRICPILDIPPNGSVDYVVCSSKHLQSQASQSQSKILEIIAFPSNKCVGQIQVADLSQIKYNSQNPKESALLPTSIIKAHKNPIKLVRLNRQGTMVATCSVQGTLIRIFSTHNGTLIKEFRRGVDKADIYEMSFSPNGSKLAVLSNKQTLHIFQIFETTNTETNTPDHSRAN------------------GSSHPLKNYIPKGLWRPKYLDSVWSICNAHLKNPIFDAHRNDNSGDVTHDNEFYKDRCRIGWCQDSNNREQDDSLVLVWQNSGIWEKFVILEKEQQDSSKTHYSLNESLRNEDTKSAGEPTRWELVRESWREL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :: . :*** .**: . . ** ::. :*:.. : : :.. ..**:* * :*:**** .. :. .::::*** . : * :: * * * :*****: : :: * : : : . : : .. . . . .::* *. * ::: : **. : : *. :* :**.. :*******.* * :.*.*** : *:*: : :. : : * *:: * *:* .. . : :*:.* ** : : . . . : .* : : : : ", "identical_positions": 65, "similar_positions": 105, "identity": "13.57%" }, { "cls_id": "homologset.oma.814987", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5MNZ9-1", "uniprot_id": "WIPI1_HUMAN", "id": "Q5MNZ9-1", "name": "WD repeat domain phosphoinositide-interacting protein 1", "aln": "MEAEAADAPPGGVESALSCFSFNQDCTSLATGTKAGYKLFSLSSVEQLDQVHG-SNEIPDVYIVERLFSS-----SLVVVVSHTKPRQMNVYHFKKGTE--ICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKDMKLLKTLLDIPANPTGL-----------CALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFR--RGMKRYVTISSLVFSMDSQFLCASSNTETVHIF-----KLEQ-------------------------VTNSRPEEPSTWSGYMGKMFMAATN-----------YLPTQVSDMMHQ-------DRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECVLIKTHSLLGSGTTEENKENDLRPSLP-----QSYAATVARPSAS-SASTVPG----YSEDGG--ALRGEVIPEH--EFATGPVCLDDE---NEFPP----------------------------IILCRGNQKGKTKQS---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A5G2QUZ7-1", "uniprot_id": "A0A5G2QUZ7_PIG", "id": "A0A5G2QUZ7-1", "name": "WD repeat domain phosphoinositide-interacting protein 1", "aln": "MEAEAAGRPPGRVEAALSCFSFNQDCTSLAIGTKAGYKLFSLSSVEQLDQVHG-SNEIPDVYIVERLFSS-----SLVVVVSHTKPRQMNVYHFKKGTE--ICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKDMKLLKTILDIPANPTGL-----------CALSINHSNSYVAYPGSLTTGEIVLYDGHSLKTLCTIAAHEGTLAAIAFNAAGSKLASASEKGTVIRVFSVPEGQKLYEFR--RGMKRYVTISSLVFSMDSQFLCASSNTETVHIF-----KLEH-------------------------LTNSRPEEPSTWSGYMGKMFLAASN-----------YLPAQVSDMMNQ-------DRAFATGRLHFSGQRNICTLSTIQKLPRLLVASSDGHLYIYNLDPQDGGDCVLIKTHSLLGSGTTEENKENDLKPSLP-----QSYAATVARPSPS-SASTVPG----YSEDGG--ALRGEVIPEH--EFATGPVCLDDE---NEFPPPQSRRVCG-AACSRPRRPAHLTALLWNNRVLIWGVPAASLHSEARRP-----", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q8R3E3-1", "uniprot_id": "WIPI1_MOUSE", "id": "Q8R3E3-1", "name": "WD repeat domain phosphoinositide-interacting protein 1", "aln": "MEAEAADAPPGRVEAALSCFSFNQDCTSLAIGTKAGYKLFSLSSVEQLDQVHG-SNEIPDVYIVERLFSS-----SLVVVVSHTKPRQMNVYHFKKGTE--ICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKDMKLLKTVLDIPSNPTGL-----------CALSINHSNSYLAYPGSQSTGEIVLYDGNSLKTVCTIAAHEGTLAAITFNSSGSKLASASEKGTVIRVFSVPEGQKLYEFR--RGMKRYVTISSLVFSMDSQFLCASSNTETVHIF-----KMEH-------------------------LTDSRPEEPSTWSGYMGKMFMAATN-----------YLPAQVSDMMNQ-------DRAFATGRLNFSGQKNICTLSTIQKLPRLLVASSDGHLYIYNLDPQDGGECVLIKTHSLLSSGTTEENKENDLRPSLP-----PSYAATVARPSTS-AASTVPG----YSEDGG--ALRGEVIPEH--EFATGPVCLDDE---NEFPP----------------------------IILCRGSQKGKTKQS---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8L2Q1U4-1", "uniprot_id": "A0A8L2Q1U4_RAT", "id": "A0A8L2Q1U4-1", "name": "WD repeat domain phosphoinositide-interacting protein 1", "aln": "MEAEAADAPPGRVEAALSCFSFNQDCTSLAIGTKTGYKLFSLSSVEQLDQVHG-SNEIPDVYIVERLFSS-----SLVVVVSHTKPRQMNVYHFKKGTE--ICNYCYSSNILSIRLNRQRLLVCLEESIYIHNIKDMKLLKTLLDIPSNPTGL-----------CALSINHSNSYLAYPGSQSTGEIVLYDGNSLKMVCTIAAHEGTLAAITFNSSGSKLASASEKGTVIRVFSVPEGQKLYEFR--RGMKRYVTISSLVFSMDSQFLCASSNTETVHIF-----KLEQ-------------------------LTDSRPEEPSTWSGYMGKMLTAATN-----------YLPAQVSDMMNQ-------DRAFATGRLNFSGQKNICTLSTIQKLPRLLVASSDGHLYIYNLDPQDGGECVLIKTHSLLSSGTAEENKENDLRPSLP-----PSYAATVARPSAS-TASTVPDNLVPWKSEGQNEAVLTRSLPQKSGQPLSGGFGKNKESGRNGMQSMLWAERGGRQEAWAPHCLSHRPWSAPLPKPLSLGCQWARRMLESHNAIQATV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1P1I7-1", "uniprot_id": "F1P1I7_CHICK", "id": "F1P1I7-1", "name": "", "aln": "MEAAAEALGG---PAALSCFSYNQDCTSLAIGTTTGYRLFSLSSVEQLDQVHE-SNEIPDVYIVERLFSS-----SLVVVVSHAKPQQMNVYHFKKGTE--ICNYSYSSNILSIRLNRQRLIVCLEESIYIHNIKDMKLLKTILDTPPNTTGL-----------CALSINHANSYLAYPGSATSGEIALYDGNTLKTACTIAAHDGPLAALTFNSTGSKLASASEKGTVIRVFSIPGGQKLYEFR--RGMKRYVNISSLVFSMDSQFLCASSNTETVHIF-----KLEH-------------------------LTDSRPEEPPTWTGYMGKMFQAATN-----------YLPAQVSGMMNQ-------DRAFATVRLNISGQRNICALSTIQKLPRLLVTTSDGHLYIYNLDPQDGGECVLIQKHSLLGSGKMEENKENDLQPPLP-----QSYAATVARQSTVPSTSTMPG----YSEDGG--ALRGEVIPEH--EFATGPVCLDDE---NEFPP----------------------------IILCRGGQPGKAKRS---------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9VIE1-1", "uniprot_id": "Q9VIE1_DROME", "id": "Q9VIE1-1", "name": "", "aln": "--------------MTTYQMNFNQDFTSLSVLSPTGLRLFSISSQDKVEEIFA-KDNTEQIRIVERLFNS-----SLVVLVTAQKPNCLKMLHFKKKQD--ICNCFYPSEILCVRMNRQRLIVCLAESIHIHDIRDMKILHSIENIAPNEQGL-----------CALSLN---SHLAFPVCQTSGELRIFNASKLRTGMTIRAHDTSLSALAFSPSGALLATASERGTVIRVFCVKNGQRVQEFR--RGVS-CVRIASLVFSASGDFLCASSNTETVHVF-----KIDTRAVETVELKAIADVAAKSENSAKEAVASTAAEESCRPVASWGGMFSKAVSSL---------LLPTQVSEVLAQ-------DRSFATVQLAQGGLKHICALTRVQKEPRLLIACEDGFLYVHEFPAERGGPCKLMSVHDLR--GALEDVIELELSESVQRSQTKPSNPSTVTQPSLTMLKSCAAS-VLIENPDPMQDNSYASILKGDQADAMSDSAKFRKLCDAIDTPT-----------------------------KLYDERQFPPVAITAKD------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q32KJ9-1", "uniprot_id": "ARSG_RAT", "id": "Q32KJ9-1", "name": "Arylsulfatase G", "aln": "MGWLFLKVLLVGMVFSGLLYPFVDFSISGETRAPRPNIVIILADDMGWGDLGANWAETKDTTNLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGVTHNFAVTSVGGLPLNETTLAEVLQQAGYVTAMIGKWHLGHHGSYHPSFRGFDYYFGIPYSNDMGCTDNPGYNYPPCPACPQSDGRWRNPDRDCYTDVALPLYENLNIVEQPVNLSGLAQKYAERAVEFIEQASTSGRPFLLYVGLAHMHVPLSVTPPLANPQSQRLYRASLQEMDSLVGQIKDKVDHVAKEN---TLLWFAGDNGPWAQKCELAGSMGPFSGLWQTHQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSLLDIFPTVIALAGASLPPNRKFDGVDVSEVLFGKSQTGHRVLFHPNSGAAGEYGALQTVRLDRYKAFYITGGAKACDGGVGPEQHHVSPLIFNLEDDAAESSPLQK---GSPEYQELLPKVTRVLADVLQDIADDNSSQADYTQDPSVTP------------------------------CCNPYQITCRCQPGE-------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * : :: ::. :: : : :::: .. .: . .: .* .: : : : :.: : :*. * * :: :: : . * . .. *: . : * .: . * . :. :: :: . .. . :*:.. : . *: . : : : ::. : . ..: * :* * :. *:: ::.: . * . * :*. : . * :. * .. : :: *: . *. :.. . .* :. * . . . . * : : . . . ", "identical_positions": 25, "similar_positions": 122, "identity": "4.39%" }, { "cls_id": "homologset.oma.814988", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2Y0-1", "uniprot_id": "WIPI4_RAT", "id": "Q5U2Y0-1", "name": "WD repeat domain phosphoinositide-interacting protein 4", "aln": "---------------------------MTQQPLRGVTSLHFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSVGLVEMLHRSNLLALVGGGSSPKFSEISVLIWDDAREGKDSKDKLVLEFTFTKPVLAVRMRHDKIVIVLRNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLV---------------------------------------------------SKEKLVELRRGTDPATLYCINFSHDSSFLCASSDKGTVHIFALKDTRLNR--------------RSALARVGKVGP---------MIGQYVDSQWSLASFTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDICDDDDF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3HNC1-1", "uniprot_id": "G3HNC1_CRIGR", "id": "G3HNC1-1", "name": "WD repeat domain phosphoinositide-interacting protein 4", "aln": "---------------------------MTQQPLRGVTSLHFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSVGLVEMLHRSNLLALVGGGSSPKFSEISVLIWDDAREGKDSKDKLVLEFTFTKPVLAVRMRHDKIVIVLRNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKPGTSSAPFTINAHQSDVACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYCINFSHDSSFLCASSDKGTVHIFALKDTRLNR--------------RSALARVGKVGP---------MIGQYVDSQWSLASFTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDICDDDDF", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q91VM3-1", "uniprot_id": "WIPI4_MOUSE", "id": "Q91VM3-1", "name": "WD repeat domain phosphoinositide-interacting protein 4", "aln": "---------------------------MTQQPLRGVTSLHFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSVGLVEMLHRSNLLALVGGGSSPKFSEISVLIWDDAREGKDSKDKLVLEFTFTKPVLAVRMRHDKIVIVLRNRIYVYSFPDSPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKPGTSSAPFTINAHQSDVACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYCINFSHDSSFLCASSDKGTVHIFALKDTRLNR--------------RSALARVGKVGP---------MIGQYVDSQWSLASFTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDICDDEDF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8V0XAQ9-1", "uniprot_id": "A0A8V0XAQ9_CHICK", "id": "A0A8V0XAQ9-1", "name": "", "aln": "---------------------------MAQG--RGVNSLRFNQDQSCFCVAMDSGVRIFNVEPLMEKGHLDAEQVGSVGLVEMLNRSNLLAIVGGGSNPKFPDVSVLIWDDARE--DPKDKLVLEFTFPKPVLAVRMRHDKLVVVLQSRIYVFSFPDNPTKLFEFDTRDNPKGICDLCPSLEKQLLVFPGHKCGSLQLVDLGSAAPGTSVAPVTINAHQSEVGCAALSPPGTLLASASRRGTLLRLFDTHSRLRLLELRRGTDPATLYCLSFSADSAFLCASSDRGTLHVFALRDTRLNR--------------RSALARVGGVGP---------VLRPYAESQWSLCSFALP-EGTAQCAFG-TATHGPTSVIAVCSDGTFQKFLFSPGGSCNRAAFDVFLDICDDDDF", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q0WPK3-1", "uniprot_id": "AT18D_ARATH", "id": "Q0WPK3-1", "name": "Autophagy-related protein 18d", "aln": "MDPRRNFQPGGYDSRNTFTSGSFGPPDFGESDEAELVSVSWNQDYSCFAAGTSHGFRIYNCEPFKETFRRELKDGG-FKIVEMLFRSNILALVGGGPNSQYPSNKVLIWDDHQG------RCISEFTFRSEIRAVKLRRDRIVVVLEHKIYVYNFMD-LRLLHQIENMANPRGLCCLSHHMNTSVLACPGIRRGEVRVEHFGLN------MVQIINAHDSNIACMTLTLDGLLLATASTKGTLIRIFNTMDGTRLQEVRRGVDRADIYSIALSPNVQWLAVSSDKGTVHIFSLRVRVIGEDAYSTEHETSSNSLQPLVSPASGANPGSSLSFLRGVLPKYFSSEWSFSQFHVPEVTQYFAAFG-----AQNTIAIIGLDGSFYRCNFDPVNGGEMTQLEHFHFLKQDSPR", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : *: :*** ***. . . *.**:* **: *. : : :: * . :**** ***:**:****...::.. .****** : : : **** . : **::*:*::*:**. :***:.* * *.:::. **:*:* *. ::..:*. ** : *.::: . :* *:***.* * :*.: :* : :*..***:**:*:*:*: :.. :. :: .. ..* :: * .*:**:..* :* .*** .:: : **:* : * * .. : :: : : :*. ", "identical_positions": 94, "similar_positions": 114, "identity": "22.93%" }, { "cls_id": "homologset.oma.814989", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8V1AK95-1", "uniprot_id": "A0A8V1AK95_CHICK", "id": "A0A8V1AK95-1", "name": "WD repeat domain phosphoinositide-interacting protein 3", "aln": "MNLLPAN--PHGNGLLYAGFNQDHELLITSVGKHR-MLRTAGRLQNGSLALFARCEKREKPFLRRGSVCLLLLS----QCINSTSPMRCFACGMENGFRVYNADPLKEKEKQEFPEGG-VGHVEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMIKVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQIMDLANTEKPPVDIPAHEGILSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQDASLICVSSDHGTVHIF----------------AAEDPKRNKQSSLASAS-FLPKYFSSKWSFSKFQVPSGSPCICAFGTEPNAVLAICADGSYYKFLFN--QKGECSRDVYAQFLEMTDDKL", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q93VB2-1", "uniprot_id": "AT18A_ARATH", "id": "Q93VB2-1", "name": "Autophagy-related protein 18a", "aln": "MATVSSSSWPNPNPNPDSTSASDSDSTFPSHRDRVDEPDSLDSFSSMSLNSDEPNQTSNQSPLSPPTPNLPVMPPPSVLHLSFNQDHACFAVGTDRGFRILNCDPFREIFRRDFDRGGGVAVVEMLFRCNILALVGGGPDPQYPPNKVMIWDDHQGRCIGELSFRSDVRSVRLRRDRIIVVLEQKIFVYNFS-DLKLMHQIETIANPKGLCAVSQGVGSMVLVCPGLQKGQVRIEHYAS--KRTKFVMAHDSRIACFALTQDGHLLATASSKGTLVRIFNTVDGTLRQEVRRGADRAEIYSLAFSSNAQWLAVSSDKGTVHVFGLKVNSGSQVKDSSRIAPDATPSSPSSSLSLFKGVLPRYFSSEWSVAQFRLVEGTQYIAAFGHQKNTVVILGMDGSFYRCQFDPVNGGEMSQLEYHNCLKPPSVF-", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :.:. *: * : .* : :.* .: : . :.. ** :. ::. * : * ::. :. .. *** * :.***: *.**::* :::* .** *. ******** ******* .*:*********** : : : *:.* ::*::*:******:***:. * *:.*: : : :* :** ******.:. . .. :*. ** :.*:*:* . *. * . : **:. ::*:**. :* :****.****:***:* .* * **:***:: *:**.: *..:*. :.****:****:* *.: . . .***: . .**:****:**.::*:: .*: *.*** : *:*: : ***:*: *: : ** *: * : *: .. ", "identical_positions": 153, "similar_positions": 136, "identity": "35.66%" }, { "cls_id": "homologset.oma.815069", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVL6-1", "uniprot_id": "TSN13_RAT", "id": "Q5FVL6-1", "name": "Tetraspanin-13", "aln": "MVCGGFSCSKNCLCALNLLYTLVSLLLIGIAAWGIGFGLISSLRVVGVVIAVGIFLFLIALVGLIGAVKHHQVLLFFYMIILLLVFIVQFSVSCACLALNREQQGQLLEVGWNNTAS-ARNDIQRNLNCCGFRNYNP-----------------NDTCPASCAKSNQKCSSCAPIIGEYAGEVLRFVGGIGLFFSFTEILGVWLTYRYRNQKDPRANPS------AFL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D8C2-1", "uniprot_id": "TSN13_MOUSE", "id": "Q9D8C2-1", "name": "Tetraspanin-13", "aln": "MVCGGFSCSKNCLCALNLLYTLVSLLLIGIAAWGIGFGLISSLRVVGVVIAVGIFLFLIALVGLIGAVKHHQVLLFFYMIILLLVFIVQFSVSCACLALNREQQGQLLEVGWNNTAS-ARNDIQRNLNCCGFRSYNP-----------------NDTCPASCAKSTQKCSSCAPIIGEYAGEVLRFVGGIGLFFSFTEILGVWLTYRYRNQKDPRANPS------AFL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95857-1", "uniprot_id": "TSN13_HUMAN", "id": "O95857-1", "name": "Tetraspanin-13", "aln": "MVCGGFACSKNCLCALNLLYTLVSLLLIGIAAWGIGFGLISSLRVVGVVIAVGIFLFLIALVGLIGAVKHHQVLLFFYMIILLLVFIVQFSVSCACLALNQEQQGQLLEVGWNNTAS-ARNDIQRNLNCCGFRSVNP-----------------NDTCLASCVKSDHSCSPCAPIIGEYAGEVLRFVGGIGLFFSFTEILGVWLTYRYRNQKDPRANPS------AFL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3ZBV0-1", "uniprot_id": "TSN13_BOVIN", "id": "Q3ZBV0-1", "name": "Tetraspanin-13", "aln": "MVCGGFACSKNCLCALNLLYTLVSLLLIGIAAWGIGFGLISSLRVVGVVIAVGIFLFLIALVGLIGAVKHHQVLLFFYMIILLLVFIVQFSVSCACLALNQEQQAQLLEVGWNNTAS-ARDDIQRNLNCCGFRSFNP-----------------NDTCLASCVKSSHPCSPCAPIIGRYAGEVLRFVGGIGLFFSFTEILGVWLTYRYRNQKDPRANPS------AFL-", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1SEI8-1", "uniprot_id": "F1SEI8_PIG", "id": "F1SEI8-1", "name": "", "aln": "MVCGGFACSKNCLCALNLLYTLVSLLLIGIAAWGIGFGLISSLRVVGVVIAVGIFLFLIALVGLIGAVKHHQVLLFFYMIILLLVFIFQFSVSCACLALNQGQQSQLLEVGWNNTAS-ARNDIQRNLNCCGFRRLNP-----------------NDTCLASCMKSRHSCSPCAPIIGKYAGEVLQFVGGIGLFFSFTEILGVWLTYRYRNQKDPRANPS------AFL-", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A1D5P7Y2-1", "uniprot_id": "A0A1D5P7Y2_CHICK", "id": "A0A1D5P7Y2-1", "name": "", "aln": "MVCGGFACSKNCLCALNLLYTLVSLLLIGIAAWGIGFGLISSFRVVGVAIAVGIFLFFIALVGLIGAVKHHQVLLFFYMIILLLVFIVQFSVSCACLALNKEQQSQLLEVGWNNTKS-ARTDLERNLNCCGFRFFDP-----------------NETCSSDCFRS-HQCQPCAPIIEEYSGMVLRFVGGIGLFFSFTEILGVWLTYRYRNQKDPRANPS------AFL-", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9VB99-1", "uniprot_id": "Q9VB99_DROME", "id": "Q9VB99-1", "name": "", "aln": "-MCGGFTCSKNALIALNILYVMIGFLLIGVGVYARAASIVTNLPIVGGILACGVILICISMLGLAGAVKHHQVMLFFYMIILFMLFLIQFSIASSCLAVNSEQQQQFAEQGWMTVPTDLRKQVQDSLKCCGFNATAPSTTSVVPPSNEPSCELINQQCCAHSSEPDCRCEPCGPLLEDKIDYAFKLCGGLGIFFSFTEVLAVFLARRYRNQHDPCYLPARAVFPHDYLY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :****:****.* ***:**.::.:****:..:. . .:::.: :** :* *::*: *:::** ********:********:::*:.***::.:***:* ** *: * ** .. : * ::: .*:****. * *: * : . .. *..*.*:: . .::: **:*:******:*.*:*: *****:** *: :* ", "identical_positions": 89, "similar_positions": 74, "identity": "38.86%" }, { "cls_id": "homologset.oma.815070", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z967-1", "uniprot_id": "D3Z967_RAT", "id": "D3Z967-1", "name": "Tetraspanin", "aln": "---------------MARRPG------VPAAYGEEFSFVSPLVKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALAC-------LAVDPAILLIVVGVLMFLLTFCGCIGSLRENICLLQTFSLCLTIVFLLQLAAGILGFVFSDKARGKVSEIINNAIVH-YRDDLDLQNLIDFGQKKFSCCG--GISYRDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPNQA--VINTMCGQGMQALDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQVLVNQIKDQIKLQLYNQQHRADPWY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R3S2-1", "uniprot_id": "TSN33_MOUSE", "id": "Q8R3S2-1", "name": "Tetraspanin-33", "aln": "---------------MARRPG------VPAAYGDEFSFVSPLVKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALAC-------LAVDPAILLIVVGVLMFLLTFCGCIGSLRENICLLQTFSLCLTIVFLLQLAAGILGFVFSDKARGKVSEIINNAIVH-YRDDLDLQNLIDFGQKKFSCCG--GISYRDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPNQA--VINTMCGQGMQALDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQVLVNQIKDQIKLQLYNQQHRADPWY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86UF1-1", "uniprot_id": "TSN33_HUMAN", "id": "Q86UF1-1", "name": "Tetraspanin-33", "aln": "---------------MARRPR------APAASGEEFSFVSPLVKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALAC-------LAVDPAILLIVVGVLMFLLTFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVH-YRDDLDLQNLIDFGQKKFSCCG--GISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQA--VINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQILVNQIKDQIKLQLYNQQHRADPWY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1MWA6-1", "uniprot_id": "F1MWA6_BOVIN", "id": "F1MWA6-1", "name": "Tetraspanin", "aln": "---------------MARRPG------APAAYGEDFSFVSPLVKYLLFFFNMLFWVISMVMVAVGVYARLMKHEEAALAC-------LAVDPAILLIVVGILMFLLTFCGCIGSLRENICLLQTFSLCLTVVFLLQLAAGVLGFVFSDKVRGKVSEIINNAIVH-YRDDLDLQNLIDFGQKEFSCCG--GISYKDWSLNMYFNCSEDNPSRERCSVPYSCCLPTPNQA--VINTMCGQGMQALDYLEASKVIYTNGCIDRLVNWIHSNLFVLGGVALGLAIPQLVGILLSMILVSQIKDQIKLQLYNQQHRADPWY", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1SMQ2-1", "uniprot_id": "F1SMQ2_PIG", "id": "F1SMQ2-1", "name": "Tetraspanin", "aln": "---------------MARRPR------APAAYGEDFSFVSPLVKYLLFFFNMLFWVISMVMVAVGIYARLMKHAEAALAC-------LAVDPAILLIVVGVLMFLLTFCGCIGSLRENICLLQTFSLCLTIVFLLQLAAGVLGFVFSDKARGKVNEIINNAIVH-YRDDLDLQNLIDFGQKKFGCCG--GISYKDWSLNMYFNCSEDNPSRERCSVPYSCCLPVPNQA--VINTMCGQGMQALDYLEASKIIYTNGCIDRLVNWIHSNLFVLGGVALGLAIPQLVGILLSMILMSQIKDQIKLQLYNQQHRADPWY", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q5RH71-1", "uniprot_id": "TSN33_DANRE", "id": "Q5RH71-1", "name": "Tetraspanin-33", "aln": "---------------MGNAKR------ATQN-DEDYTFVSPVVKYLLFFFNMIFWIISLVLISIGVYSRIVKH-ETALAC-------LTVDPALILMVVGILMFFITFCGCVGSLRENICLLQTFCIFLTIMFLLQLLAGVLGFVFSDKARGKVTDMFDNAIKH-YRDDLDLQNLIDYGQKQFNCCG--GISFMDWSKNMYFNCSDDNPSRERCSVPFSCCLHAKEET--IINTMCGHGMQALNYLAASAFINTNGCIDILVNWIHSNLFLLGGIALGLTIPQLVGILLSQVLINQIQDQIKLQNYNQQHRSDPWS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4X6-1", "uniprot_id": "Q9W4X6_DROME", "id": "Q9W4X6-1", "name": "Tetraspanin", "aln": "MSNYRYQGAGLGGVGMAGGRGYSGIEVHEVMHPHHFTYVSQCVKYMIFLLNFVFWLFGGLLLGIGVYAFRDKWEDANGSVRLENFYDVFLNISLVMILAGTVIFLVSFSGCVGALRENTFLLKFYSMCLLLFFLLEMAIAIVCFVCPQYMNTFLEKQFTHKIIHSYRDDPDLQNFIDFAQQEFKCCGLSNSGYQDWSKNEYFNCS--SPSVEKCGVPYSCCINATDISSGLVNIMCGYGVQNAPVPEATKLIWTSGCIEIVRVWAEHNLYVIAGNALGIALIQLLVIYLAKTLEGQIELQKSRWLA----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. ..:::** ***::*::*::**::. :::.:*:*: * :: : : :: ::::::.* ::*:::*.**:*:**** **: :.: * .***:: .:: ** .: . : . : : * * **** ****:**:.*::* *** . .: *** * ***** .** *:*.**:***: . : : ::* *** *:* *: .* *.***: : * . **:::.* ***::: **: * *: * .**: * . ", "identical_positions": 93, "similar_positions": 97, "identity": "29.43%" }, { "cls_id": "homologset.oma.815071", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAV9-1", "uniprot_id": "D4AAV9_RAT", "id": "D4AAV9-1", "name": "Tetraspanin-9", "aln": "--MEKSSSEDSSIHRSPSLDSKDSDFAKPSTSGRPFGRGFTAGAFYGTAGSRGQSRTEAGIKTDKYNAPKGSKYVVFYLDLSFVFLLEFKKCNMARGCLCCLKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSPSFPSLSAANLVIAIGTIVMVTGFLGCLGAIKENKCLLLSFFIVLLIILLAELILLILFFVYMDKVNENAKQDLKEGLLLYNTENNVG------LKNAWNIIQAEMRCCGVTDYTDWYPVL---GENTVPDRCCMENSQ----------------GCGRN-STTPLWKTGCYEKVKLWFDDNKHVLGTVGMCFLIMQILGMAFSMTLFQHIHR-----TGKKYDA-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A9J7JY92-1", "uniprot_id": "A0A9J7JY92_CRIGR", "id": "A0A9J7JY92-1", "name": "Tetraspanin-9", "aln": "MSMEKSSSEDSSIHRSPSLDSKDSDFAKPSTSGRPFGRGFTAGAFYGTAGSRGQSHTEAGVKTDKYNAPKGSKYVVFYLDLSFVFLLEFKKCNMARGCLCCLKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSPSFPSLSAANLVIAIGTIVMVTGFLGCLGAIKENKCLLLSFFIVLLVILLAELILLILFFVYMDKVNENAKKDLTEGLLLYNTENNVG------LKNAWNIIQAEMRCCGVTDYTDWYPVL---GENIVPDRCCMENSQ----------------GCGRN-TTTPLWRTGCYEKVKLWFDDNKHVLGTVGMCILVMQILGMAFSMTLFQHIHR-----TGKKYDA-----------------", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "O75954-1", "uniprot_id": "TSN9_HUMAN", "id": "O75954-1", "name": "Tetraspanin-9", "aln": "---------------------------------------------------------------------------------------------MARGCLCCLKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSPSFPSLSAANLVIAIGTIVMVTGFLGCLGAIKENKCLLLSFFIVLLVILLAELILLILFFVYMDKVNENAKKDLKEGLLLYHTENNVG------LKNAWNIIQAEMRCCGVTDYTDWYPVL---GENTVPDRCCMENSQ----------------GCGRN-ATTPLWRTGCYEKVKMWFDDNKHVLGTVGMCILIMQILGMAFSMTLFQHIHR-----TGKKYDA-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BJU2-1", "uniprot_id": "TSN9_MOUSE", "id": "Q8BJU2-1", "name": "Tetraspanin-9", "aln": "---------------------------------------------------------------------------------------------MARGCLCCLKYTMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSPSFPSLSAANLVIAIGTIVMVTGFLGCLGAIKENKCLLLSFFIVLLIILLAELILIILFFVYMDKVNENAKQDLKEGLLLYNTENNVG------LKNAWNIIQAEMRCCGVTDYTDWYPVL---GENTVPDRCCMENSQ----------------GCGRN-STTPLWRTGCYEKVKLWFDDNKHVLGTVGMCILIMQILGMAFSMTLFQHIHR-----TGKKYDA-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06AA5-1", "uniprot_id": "TSN9_PIG", "id": "Q06AA5-1", "name": "Tetraspanin-9", "aln": "---------------------------------------------------------------------------------------------MARGCLCCLKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSPSFPSLSAANLVIAIGTIVMVTGFLGCLGAIKENRCLLLSFFIVLLIILLAELILIILFFVYMDKVNENARKDLKEGLLLYNSENNVG------LKNAWNIIQAEMHCCGVTDYTDWYPVL---GENTVPDRCCMENSQ----------------GCGRN-STTPLWKTGCYEKVKMWFDDNKHVLGTVGMCILIMQILGMAFSMTLFQHIHR-----TGKKYDA-----------------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "M9PDV2-1", "uniprot_id": "M9PDV2_DROME", "id": "M9PDV2-1", "name": "Tetraspanin", "aln": "---------------------------------------------------------------------------------------------MGNAGYTCIRRTFCWLNIILWLCSCAFLGAGLWLRLSYAGYATLLPQHAGLSADTIFMGIGGTGFVVSFFGCCGAWVQSRCLLVLYFMLIVMLFMSEFLVGSIAFLFRGGLGRTLANELRFGIERHYNSSDRGSLVAPSVASIWDSVQQSFECCGVSSYEDWYDIQSWPGRRWVPESCCRTLYDQRQVLTEGSGDGMMRPDCGRSENPSLWWDKGCAHSLQSWFTGQLNVVGAVGLGIAFVQLFGLITSMLLFCTVKHKRASDTYKSYSPSIDPQTRTSSWEDXTRL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *... *:: : :*:*:***.*.:**.*:** :* ..:**: *....*** .:.:.** :*..*:** ** :.:***: :*:::::::::*::: : *:: . :... ::* *: : ...: * : . *: :* .:.****:.* *** : *.. **: ** : .***. .: * .** ..:: ** .: :*:*:**: : .:*::*: ** ** ::: * *.*.. ", "identical_positions": 73, "similar_positions": 106, "identity": "19.21%" }, { "cls_id": "homologset.oma.815072", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q99J59-1", "uniprot_id": "TSN1_MOUSE", "id": "Q99J59-1", "name": "Tetraspanin-1", "aln": "MQCFKFIKVMMFLFNLLIFLCGAALLAVGIWVSVDGTSFLKVFGSLSSSAMQFVNVGYFLIAAGAVLFILGFLGCYGAHSENKCVLMMFFSILLIIFIAEIAGAVVALVYTTLAEQFLTLLVVPAIEKDYGYQTDFTQVWNTTMEELHCCGFNNYTDFNASRFVKENK-VFPPPCCAN-PGNHTVEPCTEEKAKSMKVQGCFKEILHRIRANAVTVGGVAVGVAALELAAMVVSMYLYCNLK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYR9-1", "uniprot_id": "TSN1_RAT", "id": "Q6AYR9-1", "name": "Tetraspanin-1", "aln": "MQCFKFIKVMMILFNLLIFLCGAALLAVGIWVSVDGTSFLKAFGSLSSSAMQFVNVGYFLIAAGAVLFILGFLGCYGAHSENKCVLMMFFSILLIIFIAEIAGAVVALVYTTMAEQFLTFLVVPAIEKDYGYQTEFTQVWNSTMEGLHCCGFNNYTDFNSSRFVKENK-VFPPFCCANNTDSHTVEPCTEDKAKSMNVQGCFKQILQKIRTNAVTVGGVAVGVAALELAAMVVSMYLYCNLK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8C2LY71-1", "uniprot_id": "A0A8C2LY71_CRIGR", "id": "A0A8C2LY71-1", "name": "Tetraspanin", "aln": "MKCFRFIKVMMILFNLLIFLCGAALLAVGIWVSVDGTSFLKIFGSQSSSALQFVNVGYFLIAAGAVVFILGFLGCYGAHSENKCALMMFFVILLIIFIAEIAAAVVALVYTTMAEQFLTLLVVPAIRDDYGNQTEFTNVWNSTMEGLKCCGFNGYTDFNNSSYLKETS-FFPPYCCFNSTSGILEKPCNEEKAKQLEVQGCFKQLLHSIRTNAVTAGGVAVGIAALELAAMIVSMYLYCNLE----", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "O60635-1", "uniprot_id": "TSN1_HUMAN", "id": "O60635-1", "name": "Tetraspanin-1", "aln": "MQCFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAAGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAIKKDYGSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENS-AFPPFCCNDNVTNTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNLQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3T0S3-1", "uniprot_id": "TSN1_BOVIN", "id": "Q3T0S3-1", "name": "Tetraspanin-1", "aln": "MGCFNFIKVMMILFNMLIFLCGAALLAVGIWVSVDGPSFVKIFGPMSSSAMQFVNVGYFLIAAGAVLFALGFLGCYGAQTESKCALMTFFFILLLIFIAEVAAAVVALVYTTLAENFLTAVVVPNIKKEYGSQKDFTQVWNSTMAGLKCCGFTNYTDFEGSPYVRKNG-TFPPYCCYDSVNNSFMEPCNNFTAHNMSVQGCFKQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNLE----", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1S3V5-1", "uniprot_id": "F1S3V5_PIG", "id": "F1S3V5-1", "name": "Tetraspanin", "aln": "MRCFSFIKTVMILFNLLIFLCGAALLAVGIWVSVDGPSFMKVFGPLSSSAMQFVNVGYFLIAAGAVLFALGFLGCYGAQTENKCALMMFFFILLLIFIAEIAAAVVALVYTSMAEHFLTLLVVPAIKKDYGSQKDFTQVWNSTMEGLKCCGFNNYTDFEGSPYYTENK-VFPPYCCFDPGNGTAVEPCTRDEAQNKTVQGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNLK----", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A8M6Z7L3-1", "uniprot_id": "A0A8M6Z7L3_DANRE", "id": "A0A8M6Z7L3-1", "name": "Tetraspanin", "aln": "MGCFTFVKALMVMFNLLICLAGICVATVGIWATVYENSFMNILPPFNDKIWSHVNVGIFCICIGAVMTWLGMIGCCGAQKESKCLLIMFFSIVLIICIAEVAAAVVTLVYSSYAEIFLRLWAIPGLKEQYGKNQIFTNLWNSTMTTLQCCGFNNYTDFSGSYYYMQNGELYPPACCLG----LELFPCDEDNADYSRVMGCFKRIVKNTKMNVNIVGGIAAGVTAIELAAMGVAMYLYCYLDKKET", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ** *:*.:*.:**:** *.* .: :****.:: **:: : . ... ..**** * *. *.*: **::** **:.*.** *: ** *:*:* ***:*.***:***:: ** ** .:* :..:** : **::**:** *:****..****. * : :. :** ** . .* . *. * ***:.:: : *. .**:*.*: .:***** *:***** *. ", "identical_positions": 101, "similar_positions": 74, "identity": "41.06%" }, { "cls_id": "homologset.oma.815073", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q62745-1", "uniprot_id": "CD81_RAT", "id": "Q62745-1", "name": "CD81 antigen", "aln": "MGVEGCTKCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTTLLYLELGDKPAPSTFYVGIYILIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQFYDQALQQAVMDD-DANNAKAVVKTFHETLNCCGSNTLTTLTTAVLRNSLCPSSSNSFTQLLK--EDCHQKIDELFSGKLYLIGIAAIVVAVIMIFEMILSMVLCCGIRNSSVY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35762-1", "uniprot_id": "CD81_MOUSE", "id": "P35762-1", "name": "CD81 antigen", "aln": "MGVEGCTKCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTSLLYLELGNKPAPNTFYVGIYILIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQFYDQALQQAVMDD-DANNAKAVVKTFHETLNCCGSNALTTLTTTILRNSLCPSGGNILTPLLQ--QDCHQKIDELFSGKLYLIGIAAIVVAVIMIFEMILSMVLCCGIRNSSVY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3HXZ3-1", "uniprot_id": "G3HXZ3_CRIGR", "id": "G3HXZ3-1", "name": "Tetraspanin", "aln": "MGVEGCTKCIKYLLFVFNFIFWLAGGVILGVALWLRHDPQTTSLLYLELGDRPAPSTFYVGIYILIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQFYDQALQQAVVDD-DANNAKAVVKTFHETLNCCGSNALTALTTSVLKNSLCPSGTNIFNSLMK--EDCHQKIDELFSGKLYLIGIAAIVVAVIMIFEMILSMVLCCGIRNSSVY", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "P60033-1", "uniprot_id": "CD81_HUMAN", "id": "P60033-1", "name": "CD81 antigen", "aln": "MGVEGCTKCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTNLLYLELGDKPAPNTFYVGIYILIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQFYDQALQQAVVDD-DANNAKAVVKTFHETLDCCGSSTLTALTTSVLKNNLCPSGSNIISNLFK--EDCHQKIDDLFSGKLYLIGIAAIVVAVIMIFEMILSMVLCCGIRNSSVY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3ZCD0-1", "uniprot_id": "CD81_BOVIN", "id": "Q3ZCD0-1", "name": "CD81 antigen", "aln": "MGVEGCTKCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTNLLYLELGDRPAPNTFYVGIYILIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQFYDQALQQAIVDD-DANNAKAVVKTFHETLNCCGSNTLMTLTTSVLKNSLCPSSGNVITNLFK--EDCHGKIDELFSGKLYLIGIAAIVVAVIMIFEMILSMVLCCGIRNSSVY", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1NW06-1", "uniprot_id": "F1NW06_CHICK", "id": "F1NW06-1", "name": "Tetraspanin", "aln": "MGVEGCTKCIKYLLFVFNFIFWLAGGIILGVALWLRHDSQTTNILYLQLGDKQAPNTFYVGIYILIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQFYDQAFQQALMADSDSSNGKAVVKTFHETLDCCGPDTMVGTLTPLWRDDLCS--KDLLKGLLKREENCHKKIDELFSGKLYLIGIAAIVVAVIMIFEMILSMVLCCGIRNSSVY", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******************:******:***********.***.:***:**:: **.**************************************************************************:***:: * *:.*.***********:***..:: *.: ::.**. : :. *:: ::** ***:****************************************", "identical_positions": 189, "similar_positions": 34, "identity": "79.08%" }, { "cls_id": "homologset.oma.815074", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P21926-1", "uniprot_id": "CD9_HUMAN", "id": "P21926-1", "name": "CD9 antigen", "aln": "MPVKGGTKCIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQETNNNNSSFYTGVYILIGAGALMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDEVIKEVQEFYKDTYNKLKTKDEPQRETLKAIHYALNCCGLAGGVEQFISDICPKKDVLETFTVKSCPDAIKEVFDNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIRRNREMV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40240-1", "uniprot_id": "CD9_MOUSE", "id": "P40240-1", "name": "CD9 antigen", "aln": "MPVKGGSKCIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQE--NNHSSFYTGVYILIGAGALMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAVWGYTHKDEVIKELQEFYKDTYQKLRSKDEPQRETLKAIHMALDCCGIAGPLEQFISDTCPKKQLLESFQVKPCPEAISEVFNNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIRRSREMV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "I3LPR3-1", "uniprot_id": "I3LPR3_PIG", "id": "I3LPR3-1", "name": "Tetraspanin", "aln": "MPVKGGTKCIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQE--NNNSSFYTGVYILIGAGALMMVVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDQVIKEVQDFYRDTYNKLKGKDDPQRETLKAIHYALDCCGLMGGVEQLLADICPQKDVLSSLPMKPCPEAIKEVFQNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIRRSREMV", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "P30932-1", "uniprot_id": "CD9_BOVIN", "id": "P30932-1", "name": "CD9 antigen", "aln": "MPVKGGTKCIKYLLFGFNFIFWLAGIAVLSVGLWLRFDSQTKSIFEQE--NNDSSFYTGVYILIGAGALMMLVGFLGCCGAVQESQCMLGLFFSFLLVIFAIEVAAAIWGYSHKEEVIKEVQKFYEDTYNKLKNKDEPQRETLKAIHIALDCCGLTGVPEQFLTDTCPPKNLIDSLKTRPCPEAIDEIFRSKFHIIGAVGIGIAVVMIFGMVFSMILCCAIRRNRDMV", "tax_id": 9913, "tax_name": "Bovine" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:**********************::***************** **.******************:*********************.*********:***:***:**::****:*.**.***:**: **:********** **:***: * **:::* ** *:::.:: :.**:**.*:* .********************:***********.*:**", "identical_positions": 179, "similar_positions": 37, "identity": "78.51%" }, { "cls_id": "homologset.oma.815075", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P24485-1", "uniprot_id": "CD53_RAT", "id": "P24485-1", "name": "Leukocyte surface antigen CD53", "aln": "----------MGMSSLKLLKYVLFFFNFLFWVCGCCILGFGIHLLVQNTYGILFRNLPFLTLGNVLVIVGSIIMVVAFLGCMGSIKENKCLLMSFFVLLLLILLAEVTLAILLFVYEKKINTLVAEGLNDSIQHYHSDNSTRMAWDFIQSQLQCCGVNGSSDWISGPPSSCPSGADVQGCYKKGQAWFHSNFLYIGIVTICVCVIQVLGMSFALTLNCQIDKTSQALGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61451-1", "uniprot_id": "CD53_MOUSE", "id": "Q61451-1", "name": "Leukocyte surface antigen CD53", "aln": "----------MGMSSLKLLKYVLFIFNLLFWVCGCCILGFGIYFLVQNTYGVLFRNLPFLTLGNILVIVGSIIMVVAFLGCMGSIKENKCLLMSFFVLLLIILLAEVTIAILLFVYEQKLNTLVAEGLNDSIQHYHSDNSTMKAWDFIQTQLQCCGVNGSSDWTSGPPSSCPSGADVQGCYNKAKSWFHSNFLYIGIITICVCVIQVLGMSFALTLNCQIDKTSQALGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A9J7F9Z6-1", "uniprot_id": "A0A9J7F9Z6_CRIGR", "id": "A0A9J7F9Z6-1", "name": "Tetraspanin", "aln": "MVKKRSYYPSMGMSSLKLLKYVLFFFNLLFWVCGCCILGFGIFFLVQNTYGVLFRNLPFLTLGNVLVIVGSIIMVVAFLGCMGSIKENKCLLMSFFVLLMIILLAEVTLAILLFVYEQKLNTYVAEGLNDSIQHYHSDNSTMAAWDFIQSHLQCCGVNSSSDWTSGPPSSCPPGADVQGCYNKAKLWFHSNFLYIGIITICVCVIQVLGMSFALTLNCQIDKTSQALGL", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "P19397-1", "uniprot_id": "CD53_HUMAN", "id": "P19397-1", "name": "Leukocyte surface antigen CD53", "aln": "----------MGMSSLKLLKYVLFFFNLLFWICGCCILGFGIYLLIHNNFGVLFHNLPSLTLGNVFVIVGSIIMVVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLTDSIHRYHSDNSTKAAWDSIQSFLQCCGINGTSDWTSGPPASCPSDRKVEGCYAKARLWFHSNFLYIGIITICVCVIEVLGMSFALTLNCQIDKTSQTIGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1S628-1", "uniprot_id": "F1S628_PIG", "id": "F1S628-1", "name": "Tetraspanin", "aln": "----------MGISSLKLLKYVLFFFNLLFWFCGCCILGFGIYLLIHNDFGVLFHKLPSLTLGNVLIIVGSIIMVVAFLGCMGSIKENKCLLMSFFVLLLIILLAEVTLAILLFVYEPKLNVYVAEGLTDSIHRYHSDNSTKAAWDSIQTFLQCCGINGTSDWHGRPPTSCPTDSQVKGCFVKAKLWFHSNFLYIGIITICVCVIQVLGMSFALTLNCQIDKTSQVLGL", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q58DM3-1", "uniprot_id": "CD53_BOVIN", "id": "Q58DM3-1", "name": "Leukocyte surface antigen CD53", "aln": "----------MGMSSLKLLKFVLFFFNLIFWFCGCCILGLGIYLLIHSKFGVLFHNLPSLTLGNVLVIVGSVIMVVAFLGCMGSIKENKCLLMSFFVLLLIILLAEVTLAILLFVYEQKLKEYVAEGLTESIQRYNSDNSTKAAWDSIQSFLQCCGVNGTSDWTSGPPASCPKGSAVKGCYIQAKQWFHSNFLYIGITTICVCVIQVLGMSFALTLNCQIDKTSQVLGL", "tax_id": 9913, "tax_name": "Bovine" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:*******:***:**::**.*******:**.:*::. :*:**::** *****:::****:************************:**::*******:******** *:: **:**.:**::*:***** *** **: *****:*.:*** . **:*** . *:**: :.: *********** *******:*******************.:**", "identical_positions": 155, "similar_positions": 47, "identity": "67.69%" }, { "cls_id": "homologset.oma.815076", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P27701-1", "uniprot_id": "CD82_HUMAN", "id": "P27701-1", "name": "CD82 antigen", "aln": "MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFIGVGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGIVTELIRDYN--SSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKGEEDNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIELLGMVLSICLCRHVHSEDYSKVPKY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40237-1", "uniprot_id": "CD82_MOUSE", "id": "P40237-1", "name": "CD82 antigen", "aln": "MGAGCVKVTKYFLFLFNLLFFILGAVILGFGVWILADKNSFISVLQTSSSSLQVGAYVFIGVGAITIVMGFLGCIGAVNEVRCLLGLYFVFLLLILIAQVTVGVLFYFNADKLKKEMGNTVMDIIRNYT--ANATSSREEAWDYVQAQVKCCGWVSHYNWTENEELMGFTKTTYPCSCEKIKEEDNQLIVKKGFCEAD-NSTVSENNPEDWPVNTEGCMEKAQAWLQENFGILLGVCAGVAVIELLGLFLSICLCRYIHSEDYSKVPKY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8V0ZLF9-1", "uniprot_id": "A0A8V0ZLF9_CHICK", "id": "A0A8V0ZLF9-1", "name": "Tetraspanin", "aln": "MGSGCLKVTKYFLFLFNLLFLILGAVILGFGIWILADKTSFISVLQNSSPSVRTGAYILVGVGSLTMLMGFLGCLGAVNEIRCLLGLYFTCLMMILITQVAAGLVIYFQQEELKGELSRIVEKLIGDYDPVNGEDKNLQDAWDYVQKQLTCCGWNGAEEWEKNPILINRSMTAYPCSCSNSSKD---AEENTGFCTLDVVVNETATHAN-WPVHRQGCVDGVQDWLKDNLGIILGVCTGVAVVELLGMILSISLCKNIHSEDYTKVPKS", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:.*:************:*:**********:******.*******.**.*:: ***:::***::*::******:*****:********. *::***:**:.* ::**: :** *:. * .:* :* . .. ::****** *:.**** . :* .* *:. . .:*****. :: ..*** . : .:.: *** :**:: .* **::*:**:*** .***::****:.***.**: :*****:**** ", "identical_positions": 140, "similar_positions": 78, "identity": "52.04%" }, { "cls_id": "homologset.oma.815078", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q58CY8-1", "uniprot_id": "TSN18_BOVIN", "id": "Q58CY8-1", "name": "Tetraspanin-18", "aln": "MEGDCLSCMKYLMFVFNFFIFLGGACLLGIGIWVMVDPTGFREIVAANPLLITGAYILLAMGGLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRGNLTREFFTKELTKHYQGSNDTDVFSATWNSVMITFGCCGVNGPEDFKYASVFRLLTLDSDEVPEACCRREPQSRDGVLLSREECLLGRDLFLNKQGCYTVILNAFETYVYLAGALAIGVLAIELFAMIFAMCLFRGIIQ", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1SHI4-1", "uniprot_id": "F1SHI4_PIG", "id": "F1SHI4-1", "name": "Tetraspanin", "aln": "MEGDCLSCMKYLMFVFNFFIFLGGACLLGVGIWVMVDPTGFREIVAANPLLITGAYILLAMGGLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELTKHYQGNNDTDVFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSDEVPEACCRREPQSRDGVLLSREECLLGRELFLNKQGCYTVILNAFETYVYLAGALAIGVLAIELFAMIFAMCLFRGIQ-", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q96SJ8-1", "uniprot_id": "TSN18_HUMAN", "id": "Q96SJ8-1", "name": "Tetraspanin-18", "aln": "MEGDCLSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELTKHYQGNNDTDVFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMCLFRGIQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A3U2-1", "uniprot_id": "D4A3U2_RAT", "id": "D4A3U2-1", "name": "Tetraspanin", "aln": "MEGDCLSCMKYLMFVFNFFVFLGGACLLGVGIWVLVDPTGFREIVATNPLLTTGAYVVLAMGGLLFLLGFLGCCGAVRENRCLLLFFFLFILIIFLVELSAAILAFIFREHLTREFFTKELTKHYQGDNDTDVFSATWNSVMITFGCCGVNGPEDFKLASVFRLLTLDTEEVPKACCRREPQTRDGVVLSREECQLGRNPFINKQGCYTVILNTFETYVYLAGAFAIGVLAIELFLMVFAMCLFRGIQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80WR1-1", "uniprot_id": "TSN18_MOUSE", "id": "Q80WR1-1", "name": "Tetraspanin-18", "aln": "MEGDCLSCMKYLMFVFNFFVFLGGACLLGVGIWVLVDPTGFREIVATNPLLTTGAYIVLAMGGLLFLLGFLGCCGAVRENRCLLLFFFLFILIIFLVELSAAILAFIFREHLTREFFTKELTKHYQGDNDTDVFSATWNSVMITFGCCGVNGPEDFKLASVFRLLTLDTEEVPKACCRREPQTRDGVVLSREECQLGRNPFINKQGCYTVILNTFETYVYLAGAFAIGVLAIELFLMVFAMCLFRGIQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8C2M5C9-1", "uniprot_id": "A0A8C2M5C9_CRIGR", "id": "A0A8C2M5C9-1", "name": "Tetraspanin", "aln": "MEGDCLSCMKYLMFVFNFFVFLGGACLLGVGIWVLVDPTGFREIVATNPLLTTGAYIVLAMGGLLFLLGFLGCCGAVRENRCLLLFFFLFILIIFLVELSAAILAFIFREHLTREFFTKELTKHYQGNNDTDVFSATWNSVMITFGCCGVNGPEDFKTASVFRLLTLDSEEVPKACCRREPQTRDGMLLSREECQLGRSPFINKQGCYTVILNTFETYVYLAGAFAIGVLAIELFLMIFAMCLFRGIQ-", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******************:********.:****:***********:**** ****::**********************:***************.************ :****************.***************************** **********::***:********:***::****** ***. *:***********:**********:********** *:********* ", "identical_positions": 219, "similar_positions": 22, "identity": "87.95%" }, { "cls_id": "homologset.oma.815079", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "E1C857-1", "uniprot_id": "E1C857_CHICK", "id": "E1C857-1", "name": "Tetraspanin", "aln": "MASPSRRLQTKPVITCLKSVLLTYTFVFWVSGIVLLAVGVWGRVSLAVYFSLLDEKATNVPFVLVGAGVVVVLLGTFGCFATCRGSTWMLKLYAMLLSLIFLIVLVAAVVGFVFRHEIKTNFESNLNLALKNYNGTADHHSEAVDTIQRTLHCCGVQNYSDWEKTEYFTQKGIPQSCCKSQDDCSVEDLRDPSKAKQKVFVDGCFFLVTSAMESKMSVVAGISFGIACFQLVGIILACCLSQYITNNQYEMV", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "F1S1M4-1", "uniprot_id": "F1S1M4_PIG", "id": "F1S1M4-1", "name": "Tetraspanin", "aln": "MASPSRRLQTKPVITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFVLIGIGTVIILLGTFGCFATCRASAWMLKLYAMFLTLIFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNATGDYRSDAVDKIQNTLHCCGVTDYRDWKDTNYYSEKGFPKSCCKLEG-CS------PQRDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQYEIV", "tax_id": 9823, "tax_name": "Pig" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************:***** ***:**::*::*****:**:*** *****:**********:* *.*::************.*:********:*:****: ****:**********..*:.* : ***:**.*.*::*:***.**.******* :* **:.*:*:::**:*:**** :. ** *.: :** :***: * : :**:*.********:*****:**:** ***: *******:*", "identical_positions": 169, "similar_positions": 57, "identity": "67.06%" }, { "cls_id": "homologset.oma.815080", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZA6-1", "uniprot_id": "CD151_RAT", "id": "Q9QZA6-1", "name": "CD151 antigen", "aln": "MGEFNEKKATCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASSTYLATAYILVVAGVVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYVYYQQLNTELKENLKDTMIKRYHQSGHEGVTNAVDKLQQEFHCCGSNNSRDWRDSEWIRSGEADSRVVPDSCCKTVVTGCGKREHASNIYKVEGGCITKLESFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLKLEHY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35566-1", "uniprot_id": "CD151_MOUSE", "id": "O35566-1", "name": "CD151 antigen", "aln": "MGEFNEKKATCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASSTYLATAYILVVAGVVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYVYYQQLNTELKENLKDTMVKRYHQSGHEGVSSAVDKLQQEFHCCGSNNSQDWQDSEWIRSGEADSRVVPDSCCKTMVAGCGKRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLKLEHY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48509-1", "uniprot_id": "CD151_HUMAN", "id": "P48509-1", "name": "CD151 antigen", "aln": "MGEFNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVALCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLKLEHY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RYZ1-1", "uniprot_id": "F1RYZ1_PIG", "id": "F1RYZ1-1", "name": "Tetraspanin", "aln": "MGEFGEKGAPCGTICLKYLLFTFNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGIVVMVTGVLGCCATFKERRNLLRLYFILLLLIFLLEIIAGVLAYVYYQQLSAELKANLKDTLSKRYRQPGHEGVTSATDKLQQEFHCCGSNNSQDWRDSEWILSGEAGDRVVPDSCCKTVVAGCGRRDHASNIYKVEGGCITRLETFIREHLRIIGAVGIGIACVQVFGMIFTCCLYKSLKLEHY", "tax_id": 9823, "tax_name": "Pig" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****.** :.***:********:*******************************.************* *****************************:*********:***.*****.:*** *****: ***:*.***.*:.*.*:*************:**:***** * **..**********:*: **:*:**************:**:**:****:***********************:*******", "identical_positions": 214, "similar_positions": 32, "identity": "84.58%" }, { "cls_id": "homologset.oma.815082", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P08962-1", "uniprot_id": "CD63_HUMAN", "id": "P08962-1", "name": "CD63 antigen", "aln": "MAVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPKNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIVFACCLVKSIRSGYEVM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1SPK8-1", "uniprot_id": "F1SPK8_PIG", "id": "F1SPK8-1", "name": "Tetraspanin", "aln": "MAVEGGMRCVKFLLYVLLLAFCACAVGLIAVGIWVQLVLNQTITQGATPGSLLPVVIIAVGAFLFLVAFVGCCGTCKENYCLMVTFAIFLSLIMLVEVAAAIAGYVFRDKVKAEFNKDFQQQMQNYPKNNHTALILDRMQEDFKCCGAANYTDWEKIL-LSPKRVPDSCCVNVTQHCGVNFNVKEIHNEGCVEKIGSWLRSNVLVAAAAALGIAFVEVLGIVFACCLVKSIRSGYEVM", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "P41731-1", "uniprot_id": "CD63_MOUSE", "id": "P41731-1", "name": "CD63 antigen", "aln": "MAVEGGMKCVKFLLYVLLLAFCACAVGLIAIGVAVQVVLKQAITHETTAGSLLPVVIIAVGAFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAVAIAGYVFRDQVKSEFNKSFQQQMQNYLKDNKTATILDKLQKENNCCGASNYTDWENIPGMAKDRVPDSCCINITVGCGNDFKESTIHTQGCVETIAIWLRKNILLVAAAALGIAFVEVLGIIFSCCLVKSIRSGYEVM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A3L7IIT8-1", "uniprot_id": "A0A3L7IIT8_CRIGR", "id": "A0A3L7IIT8-1", "name": "Tetraspanin", "aln": "MAVEGGMKCVKFLLYVLLLAFCACAVALIAIGVAVQVVLNQTITRETTPGSLLPVVIIAVGAFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAVAIAGYVFRDKVKSEFNKNFRQQMQNYLKDNKTALVLDGWQKEFECCGANNYTDWENITGMPKDRVPDSCCINITVGCGIDFKENKIHTQGCVENIGVWLRKNVLLVAAAALGIAFVEILGIIFSCCLVKSIRSGYEVM", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******:******************.***:*: .*:**.*:* : :*.************.************:********:***************.*********:* :***:.*:***:** *:*:** :** * : :**** ******:* :. .*******:*:* ** :*: . **.:****.*. ***.*:*:.***********:***:*:**************", "identical_positions": 172, "similar_positions": 46, "identity": "72.27%" }, { "cls_id": "homologset.oma.815084", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y7S7-1", "uniprot_id": "A0A8I5Y7S7_RAT", "id": "A0A8I5Y7S7-1", "name": "Tetraspanin-4", "aln": "MRRSSTDESTYRRSPSPESKEQGFARGGPFRRCSSLYGRAGAGDAGDAGGGFFGLHSNPGPKAAQARYTTPKGNKYVVFYLDLSFIFLLELKRCSMARGCLQGVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGNFATLSSSFPSLSAANLLIVTGTFVMAIGFVGCIGALKENKCLLLTFFVLLLLVFLLEATIAVLFFAYSDKIDSYAQQDLKKGLHLYGTEGNVGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCCLEFSDSCGLHEPGTWWKSPCYETVKAWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVKADTYCA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCK3-1", "uniprot_id": "TSN4_MOUSE", "id": "Q9DCK3-1", "name": "Tetraspanin-4", "aln": "-----------------------------------------------------------------------------------------------MARGCLQGVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGNFATLSSSFPSLSAANLLIVTGTFVMAIGFVGCIGALKENKCLLLTFFVLLLLVFLLEATIAVLFFAYSDKIDSYAQQDLKKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCCLEFSDSCGLHEPGTWWKSPCYETVKAWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVKADTYCA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14817-1", "uniprot_id": "TSN4_HUMAN", "id": "O14817-1", "name": "Tetraspanin-4", "aln": "-----------------------------------------------------------------------------------------------MARACLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCCLEFSESCGLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVKADTYCA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***.***.*******************************.******************:**:**********:**:***********:*************:*****:**** ***************:*********************************************:***** ******:*******.******************************************", "identical_positions": 222, "similar_positions": 14, "identity": "66.67%" }, { "cls_id": "homologset.oma.815087", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q96FV3-1", "uniprot_id": "TSN17_HUMAN", "id": "Q96FV3-1", "name": "Tetraspanin-17", "aln": "MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDVLNTQCGYDVRLKLELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFGICLAQNLVSDIKAVKANW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58DN3-1", "uniprot_id": "TSN17_BOVIN", "id": "Q58DN3-1", "name": "Tetraspanin-17", "aln": "MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWSEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDVLNTQCGYDVRLKLELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFVGIALLQIFGICLAQNLVSDIKAVKANW", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q4V8E0-1", "uniprot_id": "TSN17_RAT", "id": "Q4V8E0-1", "name": "Tetraspanin-17", "aln": "MPGKHQQFQDPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISGLTDLGGLDPVWLFVVIGGIMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELAAGILAFVFKDWIRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDVLNTQCGYDIRLKLELEQQGSIYTKGCVGQFEKWLQDNLIVVAGVLVAIALLQICGICLAQNLVSDIEAVKANW", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:**:*********************************.*********.***************:**:************************************:***********************************************************************************************:********** *:**********************::.****** ************:******", "identical_positions": 255, "similar_positions": 13, "identity": "94.44%" }, { "cls_id": "homologset.oma.815089", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U1V9-1", "uniprot_id": "TSN31_RAT", "id": "Q5U1V9-1", "name": "Tetraspanin-31", "aln": "MACGGFACSKNALCALNVVYMLVGLLLIGVAAWGKGLGVVSSIHIIGGVIAVGVFLLLIAVAGLVGAVNHHQVLLFFYMIILGLVFIFQFGISCSCLAINRNTQADVINASWWVLSNSTRHELERSFDCCGLFNLTTVHLHDDASCSALCKTRSSPCQMCGETFLKHSDKALKILGGVGLFFSFTEILGVWLAMRFRNQKDPRANPSAFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ88-1", "uniprot_id": "TSN31_MOUSE", "id": "Q9CQ88-1", "name": "Tetraspanin-31", "aln": "MVCGGFACSRNALCALNVVYMLVGFLLIGVAAWGKGLGVVSSIHIIGGVIAVGVFLLLIAVAGLVGAANHHQVLLFFYMIILGLVFIFQFGISCSCLAINRNTQADVINASWSVLSNSTRHELERSFDCCGLFNLTTLRLQDDTSCSAVCKTKSSTCQMCGERFLKHSDKALKILGGVGLFFSFTEILGVWLAMRFRNQKDPRANPSAFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q32KP1-1", "uniprot_id": "TSN31_BOVIN", "id": "Q32KP1-1", "name": "Tetraspanin-31", "aln": "MVCGGFACSKNALCALNVVYMLVGLLLIGVAAWAKGLGLVSSIHIIGGVIAVGVFLLLIAVAGLVGAVNHHQVLLFFYMIILGLVFIFQFGISCSCLAINLSKQTDVINASWWVMSNKTRDELERSFDCCGLFNLTTLDQQDYAFCTAVCKSRSPTCQMCGEKFLKHSDEALKILGGVGLFFSFTEILGVWLAMRFRNQKDPRANPSAFL", "tax_id": 9913, "tax_name": "Bovine" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.*******:**************:********.****:****************************.******************************** ..*:******* *:**.**.****************: :* : *:*:**::*..****** ******:****************************************", "identical_positions": 181, "similar_positions": 22, "identity": "86.19%" }, { "cls_id": "homologset.oma.815090", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q61470-1", "uniprot_id": "CD37_MOUSE", "id": "Q61470-1", "name": "Leukocyte antigen CD37", "aln": "MSAQESCLSLIKYFLFVFNLFFFVLGGLIFCFGTWILIDKTSFVSFVGLSFVPLQTWSKVLAVSGVLTMALALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRVRLERRVQELVLRTIQSYRTNPDETAAEESWDYAQFQLRCCGWQSPRDWNKAQMLKANESEEPFVPCSCYNSTATNDSTVFDKLFFSQLSRLGPRAKLRQTADICALPAKAHIYREGCAQSLQKWLHNNIISIVGICLGVGLLELGFMTLSIFLCRNLDHVYDRLARYR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31053-1", "uniprot_id": "CD37_RAT", "id": "P31053-1", "name": "Leukocyte antigen CD37", "aln": "MSAQESCLSLIKYFLFVFNLFFFVLGGLIFCFGTWILIDKTSFVSFVGLSFVPLQTWSKVLSVSGVLTMALALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRVRLERRVQELVLRTIQSYRTNPDETAAEESWDYAQFQLRCCGWQSPRDWNKAQMLKANGSEELFVPCSCYNSTATNDSSGFDKLFLSQLSRLGPRAKLRQTADICALPAKAHIYREGCARSLQKWLHNNIISIVGICLGVGLLELGFMTLSIFLCRNLDHVYDRLARYR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11049-1", "uniprot_id": "CD37_HUMAN", "id": "P11049-1", "name": "Leukocyte antigen CD37", "aln": "MSAQESCLSLIKYFLFVFNLFFFVLGSLIFCFGIWILIDKTSFVSFVGLAFVPLQIWSKVLAISGIFTMGIALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLERSLRDVVEKTIQKYGTNPEETAAEESWDYVQFQLRCCGWHYPQDWFQVLILRGNGSEAHRVPCSCYNLSATNDSTILDKVILPQLSRLGHLARSRHSADICAVPAESHIYREGCAQGLQKWLHNNLISIVGICLGVGLLELGFMTLSIFLCRNLDHVYNRLARYR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************************.****** ***************:***** *****::**::**.:*****************************************.:*** ::::* :***.* ***:**********.*********: *:** :. :*:.* ** ******* :*****: :**:::.****** *: *::*****:**::********:.********:********************************:******", "identical_positions": 222, "similar_positions": 42, "identity": "79.0%" }, { "cls_id": "homologset.oma.815091", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q568Y5-1", "uniprot_id": "TSN11_RAT", "id": "Q568Y5-1", "name": "Tetraspanin-11", "aln": "-MAHCKTEQDDWLLAHLKYLLFIFNFFFWVGGAAVMAVGIWTLVEKSVYLSILASSTFAASAYVLIFVGGLVMTTGFLGFGAIIREQKSCLSTYFCLLLAIFLVELVAGVLAHVYYQRLSDELKRHLHSTLTEHYGQPGAAEITASVDRLQQDFKCCGSNSSADWQHSVYILSQEAIGRQVPDSCCKTVVARCGQRAHPSNIYKVEGGCMAKLEQFLADHLLLMGAVGIGVACLQICGMVLTCCLHRRLQQHFY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D1D1-1", "uniprot_id": "TSN11_MOUSE", "id": "Q9D1D1-1", "name": "Tetraspanin-11", "aln": "-MAHCKTEQDDWLLAHLKYLLFIFNFFFWVGGAAVMAVGIWTLVEKSGYLSILASSTFAASAYILIFVGGLVMTTGFLGFGAIIREQKSCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKWHLNSTLTEHYGQPRAAEITASVDRLQQDFKCCGSNSSADWQHSAYILSQEALGRQVPDSCCKTVVARCGQRAHPSNIYKVEGGCMAKLEQFVADHLLLMGAVGIGVACLQICGMVLTCCLHRRLQQQFY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8C2LU09-1", "uniprot_id": "A0A8C2LU09_CRIGR", "id": "A0A8C2LU09-1", "name": "Tetraspanin", "aln": "-MAYCKTEQDDWLLAHLKYLLFIFNFFFWVGGAAVMAVGIWTLVEKSGYLSILASSTFPASAYILIFAGALVVTTGFLGFGAIIREQKGCLSMYFCLLLVIFLVELVAGVLAHVYYQRLSDELRQHLNSTLTEHYGQPRAAEITASVDRLQQDFKCCGSNSSADWQHSTYILSREAQGRRVPDSCCKTVVARCGQRAHPSNIYKVEGGCMAKLEQFLADHLLLMGAVGIGVACLQICGMVLTCCLHRRLQQHFY", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "A1L157-1", "uniprot_id": "TSN11_HUMAN", "id": "A1L157-1", "name": "Tetraspanin-11", "aln": "-MAHYKTEQDDWLIIYLKYLLFVFNFFFWVGGAAVLAVGIWTLVEKSGYLSVLASSTFAASAYILIFAGVLVMVTGFLGFGAILWERKGCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKQHLNRTLAENYGQPGATQITASVDRLQQDFKCCGSNSSADWQHSTYILLREAEGRQVPDSCCKTVVVRCGQRAHPSNIYKVEGGCLTKLEQFLADHLLLMGAVGIGVACLQICGMVLTCCLHQRLQRHFY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0VC33-1", "uniprot_id": "TSN11_BOVIN", "id": "Q0VC33-1", "name": "Tetraspanin-11", "aln": "-MAHYKVEQDDWLTVYLKYLLFIFNFFFWVGGAAVMAVGVWTLVEKSGYLGVLASSTFAASAYILIFAGALVMVTGFLGFGAVIREDRGCLSAYFCLLLAIFLVELVAGVLAHVYYQRLSDELKQHLTRTLAENYRQPGAAEITASVDRLQQDFKCCGSNSSADWLQSSYILSPEAEGRRVPDSCCKTVVARCGQRAHPSNIYKVEGGCISKLEQFLADHLLLMGAVGIGVACLQICGMILTCGLHRRLQLHFY", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q5RGQ1-1", "uniprot_id": "Q5RGQ1_DANRE", "id": "Q5RGQ1-1", "name": "Tetraspanin", "aln": "MGSMYKDEQGDWITVCLKYLLFVFNFLFWMGGGVVMGVGIWTLVDKGEYLSLLASSTFAVSAYILILAGGLVMVTGFLGCCAVIREQRSCLSTYFSCLLLIFLIELVAGVLAYVYYQALSEELKQHLSKTMMENYAQPGKESITQSVDRLQQDFKCCGSNNSLDWMHSVYIMSQAADSRVVPDSCCKTITPQCGRRDHPSNIYKVEGGCITKLEQFLADHLLIIGAVGIGVACLQICGMVFTCCLHRRIKLDPY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * **.**: ******:***:**:**..*:.**:****:*. **.:******..***:**:.* **:.***** *:: * :.*** **. ** ***:********:**** **:**: ** *: *:* ** .** ***************.* ** :* **: * .* ********:. :**:* ************::*****:*****::***************::** **:*:: . *", "identical_positions": 161, "similar_positions": 53, "identity": "63.39%" }, { "cls_id": "homologset.oma.815095", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJW1-1", "uniprot_id": "TSN2_RAT", "id": "Q9JJW1-1", "name": "Tetraspanin-2", "aln": "MGRFRGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGTIKDLSSEEKSPEYFYVGLYVLVGAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKDVAIRHVQSMYEEAYSDYVRDRGRGN--GTLITFHSAFQCCGKESSE---------------------------QVQPTCPKELPG---------------------HKNCIDKIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNSRDVI----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A3Q1MIJ0-1", "uniprot_id": "A0A3Q1MIJ0_BOVIN", "id": "A0A3Q1MIJ0-1", "name": "Tetraspanin", "aln": "MGRFRGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGSMKDFSSEDKSPEYFYMGLYVLVGAGALMMAVGFFGCCGATRESQCVLGSFFTCLLVIFAAEITTGVFAFIGKDVAIRHVQTMYEEAYNDYLRDKEKGN--GTLITFHSTFQCCGKESPE---------------------------QVQPTCPKELLG---------------------HKNCIDEIESIISVKLQLIGIVGIGIAGLTIFGMVFSMVLCCAIRNSRDVI----------------", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A0B4KH03-1", "uniprot_id": "A0A0B4KH03_DROME", "id": "A0A0B4KH03-1", "name": "Tetraspanin", "aln": "MG-LNGCCSCVKYLMVLINILFWLIGLTIVVTSVWMLTDPTFMLSMTQNYN--HYHIALYVFLAIGILITLGAFFGCCGVCRESQCLLVSFFCVILIVMVAQIAAGAWAFHNKDKLDDIVRAAVKSSVQEEYGQSTMSSRTVTFDTLQKNLKCCGADGPGDWATSRFNNVDRTNIVEIAVSSMNVFYNIPESCCKDNLKDNECELSRRLKFGGPLNNAIYQQGCVDKLIEIIYENWVTIFAVTAAVILLELLSLTFALSLCCAVRNQHYKAXELQNSHREITDDEKY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :.* *:***:: :*:**** * :::. .:*: . :: ::: . ::::.***::. * *: .******. *****:* *** :*:::.*::::*.:** .** *:: :.: .: : .. *: *::. ::*** :.. :: :* *: ::.*:*:: ** : * * .: * ::.: *:: ****:**.: ", "identical_positions": 63, "similar_positions": 86, "identity": "21.95%" }, { "cls_id": "homologset.oma.815096", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "E9QBC5-1", "uniprot_id": "E9QBC5_DANRE", "id": "E9QBC5-1", "name": "Tetraspanin", "aln": "MAALTGGEMCVK--YLMFVFN--FIFWIAGTAVLAVGLWLRFDPKTKSLFEGENSPYVFYTGVYILIAAGALMMVVGFFGCCGAIQESPCMLGLFFFFLLVIFAVEVAAGIWGFSNQTKVTEDITTFYRQTYDTYQQSKQEALKKTLRLFQHGLNCCGPSGNMQESLDETCPKKEGLDNLIIKSCPDAIDEVFNSKLHIIGGVGIATGVIMIFGMIFSMMLCCAIRKTREIV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8V1A2P5-1", "uniprot_id": "A0A8V1A2P5_CHICK", "id": "A0A8V1A2P5-1", "name": "Tetraspanin", "aln": "MVSWSLSSCCCLQEYSGAVPASSSETQLAGTAVLAIGLWLRFDVQTKSIFELESNNMTFYTGVYILIGAGALMMLVGFLGCCGALQESQCMLGLFFVFLFVIFALEIATAIWGFANKEKIVEELQDFYRETYE---KRSQPAAREILKAFHFALNCCGITGGLEQQLMESCPKKTLPESFTTMPCPKAIDDVFNSKLNVIGAVGLGIAVIMIFGMIFSMVLCCAIRRNREMV", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: : .. * * * :*******:******* :***:** *.. .*********.******:***:*****:*** *******.**:****:*:*:.****:*: *:.*:: ***:**: : .* * :: *: *:..***** :*.:::.* *:**** :.: .**.***:******::**.**:. .***********:******:.**:*", "identical_positions": 128, "similar_positions": 61, "identity": "55.17%" }, { "cls_id": "homologset.oma.815098", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q68VK5-1", "uniprot_id": "TSN5_RAT", "id": "Q68VK5-1", "name": "Tetraspanin-5", "aln": "--MSGKHYK--GPEVSCCIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITDLGGFDPVWLFLVVGGVMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKD--WIKDQLYFFINNNIRAYRDDIDLQNLIDFTQEYW-QCCGAFGADDWNLNIYFNCTDSN-ASRERCGVPFSCCTKDPAEDVINTQCGYDARQK--------------------------------------PEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIFIGIALLQIFGICLAQNLVSDIEAVRASW-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62080-1", "uniprot_id": "TSN5_MOUSE", "id": "P62080-1", "name": "Tetraspanin-5", "aln": "--MSGKHYK--GPEVSCCIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITDLGGFDPVWLFLVVGGVMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKD--WIKDQLYFFINNNIRAYRDDIDLQNLIDFTQEYW-QCCGAFGADDWNLNIYFNCTDSN-ASRERCGVPFSCCTKDPAEDVINTQCGYDARQK--------------------------------------PEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIFIGIALLQIFGICLAQNLVSDIEAVRASW-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62079-1", "uniprot_id": "TSN5_HUMAN", "id": "P62079-1", "name": "Tetraspanin-5", "aln": "--MSGKHYK--GPEVSCCIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITDLGGFDPVWLFLVVGGVMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKD--WIKDQLYFFINNNIRAYRDDIDLQNLIDFTQEYW-QCCGAFGADDWNLNIYFNCTDSN-ASRERCGVPFSCCTKDPAEDVINTQCGYDARQK--------------------------------------PEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIFIGIALLQIFGICLAQNLVSDIEAVRASW-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q17QJ5-1", "uniprot_id": "TSN5_BOVIN", "id": "Q17QJ5-1", "name": "Tetraspanin-5", "aln": "--MSGKHYK--GPEVSCCIKYFIFGFNVIFWFLGIAFLGIGLWAWNEKGVLSNISSITDLGGFDPVWLFLVVGGVMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKD--WIKDQLYFFINNNIRAYRDDIDLQNLIDFTQEYW-QCCGAFGADDWNLNIYFNCTDSN-ASRERCGVPFSCCTKDPAEDVINTQCGYDARQK--------------------------------------PEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIFIGIALLQIFGICLAQNLVSDIEAVRASW-", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "I3LPC5-1", "uniprot_id": "I3LPC5_PIG", "id": "I3LPC5-1", "name": "Tetraspanin", "aln": "--MSGKHYK--GPEVSCCIKYFIFGFNVIFWFLGIAFLGIGLWAWNEKGVLSNISSITDLGGFDPVWLFLVVGGVMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKD--WIKDQLYFFINNNIRAYRDDIDLQNLIDFTQEYW-QCCGAFGADDWNLNIYFNCTDSN-ASRERCGVPFSCCTKDPAEDVINTQCGYDARQK--------------------------------------PEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIFIGIALLQIFGICLAQNLVSDIEAVRASW-", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q9VMJ6-1", "uniprot_id": "Q9VMJ6_DROME", "id": "Q9VMJ6-1", "name": "", "aln": "MPAAVRKFRRETSEISCCLKYLLFASNVILWLSALLVLSVGIWAWSEKGMFRNIARLHFIA-LDPAFVLIILGGVTFLLGFMGSVGALRENTCLLGAYAIFLSVLLIAEIGFCAVAFVLKDKGWIKDQATEGLKAFIRHYREDADQQNLIDWIQEDWLQCCGIDGPKDWDSNNYFNCSSIAIGSREACGVPFSCCRRRPQEVIKNKQCGYDVRKEGYPVDRNIHERGCLRAGEDWLEAHLISVAIGCVALLVLQGMELSKIIYEKGCVQAGEEWMEHNLIIISATVIVVMFFQILGICFAQNLRADIYTQKSKWH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::: .*:***:**::*. ***:*: .: .*.:*:***.***:: **: : :. :**.::::::*** *:*** *.:******* ** :::**.:::: *: .:***:** ***** :: ** **:* * *****: ** * **** *..**: * ****:. .*** ******** : * * : *.*****.*:: :: . :** **** *:*::.** *::. .* : ::**:***:**** :** : ::.* ", "identical_positions": 123, "similar_positions": 87, "identity": "39.05%" }, { "cls_id": "homologset.oma.815103", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q62283-1", "uniprot_id": "TSN7_MOUSE", "id": "Q62283-1", "name": "Tetraspanin-7", "aln": "MASRRMETKPVITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAEN---------STNAPYVLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQNYNGNDERSRAVDHVQRSLSCCGVQNYTNWSSSPYFLDHGIPPSCCMNETDCNPLDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFIT----ANQYEMV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1RXQ7-1", "uniprot_id": "F1RXQ7_PIG", "id": "F1RXQ7-1", "name": "Tetraspanin", "aln": "MASRRMETKPVITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAEN---------STNAPYVLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQNYNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNETDCNPQDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFIT----ANQYEMV", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "B0BNE7-1", "uniprot_id": "B0BNE7_RAT", "id": "B0BNE7-1", "name": "Tetraspanin", "aln": "MASRRMETKPVITCLKTLLIIYSFVFWITGAILLAVGVWGKLTLGTYISLIAEN---------STNAPYVLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQNYNGKDERSRAVDHVQRSLSCCGVQNYTNWSSSPYFLEHGIPPSCCMNETDCNPLDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFIT----ANQYEMV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B0VEQ2-1", "uniprot_id": "B0VEQ2_DANRE", "id": "B0VEQ2-1", "name": "Tetraspanin", "aln": "MASRRMETKPVITCLKTLLIVYSFVFWITGAILLAVGLWGKFILGPYISLIAEN---------STNAPYVLIGTGTTIIVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKGTFLRTYNEAVQNYNAQDERSIAVDNVQRSLRCCGVLNYTSWFSSVYFPVNGIPPSCCANISDCNASDLRNATIAPTKVYQQGCYELVTTFIETNMGIIAGVTFGIAFSQLIGMLLACCLSRFIT----ANQYEMV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q55CW7-1", "uniprot_id": "TSPB_DICDI", "id": "Q55CW7-1", "name": "Probable tetraspanin tspB", "aln": "MVDTTNLIPNTPRYLKVPLIAFNTILWVLGLVLVIIGSIGVSFFSNFKDFTKVSKASAALSNLTTGAPAGVLVIGIFFVILTVIGCFVAGKEKLVGLVIYTMLMLIILVALIGVGGKALTLHN---DDVVKQIGNAWEDVS-NGPKNSTILKLENFLKCC------YWNST-----SSRNPLLCPKDSKGIP------------KYTDTCDSVISSKISSNLYLVGAAAVSIGVIEFICMLFALFLIIRICRAPRTKSYDYQ", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. . **. ** :. ::*: * :*: :* * :. : .: . :*.** :: * :::: ::***.: : . * :*:*:: ::::* : .* ..:.::: . .:: :* :: . :. :. :: :::. * ** * :: . * * : :. . . * .:::: :.:*: ::...:..*.. ::* **:* * * ::.*: ", "identical_positions": 39, "similar_positions": 101, "identity": "14.89%" }, { "cls_id": "homologset.oma.815105", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O60637-1", "uniprot_id": "TSN3_HUMAN", "id": "O60637-1", "name": "Tetraspanin-3", "aln": "MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRDPAYELLITGGTYA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1SJ91-1", "uniprot_id": "F1SJ91_PIG", "id": "F1SJ91-1", "name": "Tetraspanin", "aln": "MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFVIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETSSNCNGSLAYPSDLYSEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRDPAYELLITGGTYA", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q66H06-1", "uniprot_id": "Q66H06_RAT", "id": "Q66H06-1", "name": "Tetraspanin", "aln": "MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLFPAVVIMAVGALLFIIGLIGCCATIRESRCGLATFVFILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGTNSDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETARSCNGSLANPSDLYAEGCEALVVKKLQEILMHVIWAALAFAAIQLLGMLCACIVLCRRSRDPAYELLITGGTYA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QY33-1", "uniprot_id": "TSN3_MOUSE", "id": "Q9QY33-1", "name": "Tetraspanin-3", "aln": "MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLFPAVVIIAVGALLFIIGLIGCCATIRESRCGLATFVFILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGTNSDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETAKSCNGSLANPSDLYAEGCEALVVKKLQEILMHVIWAALAFAAIQLLGMLCACIVLCRRSRDPAYELLITGGTYA", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************************************************:*****:*******:*********************:******************************************.***********************************************: .****** *****:**************:********************************************", "identical_positions": 242, "similar_positions": 9, "identity": "95.65%" }, { "cls_id": "homologset.oma.815107", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O43657-1", "uniprot_id": "TSN6_HUMAN", "id": "O43657-1", "name": "Tetraspanin-6", "aln": "MASPSRRLQTKPVITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFVLIATGTVIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCKLEDCTPQRDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQYEIV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q32KU6-1", "uniprot_id": "TSN6_BOVIN", "id": "Q32KU6-1", "name": "Tetraspanin-6", "aln": "MASPSRRLQTKPVITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFVLIGTGTVIILLGTFGCFATCRASAWMLKLYAMFLTLIFLVELVAAIIGFVFRHEIKNSLKNNYEKALKQYNATGDYRSDAVDKIQSMLHCCGVTNYRDWKDTNYYSEKGFPESCCKLEDCSPQRDADKVNNEGCFIMVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQYEIV", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F7ESS4-1", "uniprot_id": "F7ESS4_RAT", "id": "F7ESS4-1", "name": "Tetraspanin", "aln": "MASPSRRLQTKPVITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFVLIGTGTVIILLGTFGCFATCRASAWMLKLYAMFLTLIFLVELVAAIVGFVFRHEIKNSFKSNYENALKEYNSTRDYRSEAVDKIQSTLHCCGVTNYRDWKGTNYYSETGFPKSCCKLEGCYPQRDADKVNEEGCFIKVMTTIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQYEIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3H5Y9-1", "uniprot_id": "G3H5Y9_CRIGR", "id": "G3H5Y9-1", "name": "Tetraspanin", "aln": "MASPSRRLQTKPVITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFVLIGTGTVIILLGTFGCFATCRASAWMLKLYAMFLTLIFLVELVAAIVGFVFRHEIKNSFKNNYENALKEYNATRDYRSEAVDKIQSTLHCCGVTNYRDWKGTTYYSETGFPKSCCKLEGCSPQRDADKVNEEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQYEIV", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****************************************************************.*********************************:*********:***********:*.***:***:**:* ****.******. *******:****..*.****.***:******.* *********:***** *** *****************************************", "identical_positions": 222, "similar_positions": 18, "identity": "90.61%" }, { "cls_id": "homologset.oma.815108", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q12999-1", "uniprot_id": "TSN31_HUMAN", "id": "Q12999-1", "name": "Tetraspanin-31", "aln": "MVCGGFACSKNALCALNVVYMLVSLLLIGVAAWGKGLGLVSSIHIIGGVIAVGVFLLLIAVAGLVGAVNHHQVLLFFYMIILGLVFIFQFVISCSCLAINRSKQTDVINASWWVMSNKTRDELERSFDCCGLFN---LTTLYQQDYDFCTAICKSQSPTCQMCGEKFLKHSDEALKILGGVGLFFSFTEILGVWLAMRFRNQKDPRANPSAFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3HW56-1", "uniprot_id": "G3HW56_CRIGR", "id": "G3HW56-1", "name": "Tetraspanin-31", "aln": "MVCGGFACSKNALCALNVVYMLVGLLLIGVAAWGKGLGLVSSIHIIGGVIAVGVFLLLIAVAGLVGAVNHHQVLLFFYMIILGLVFIFQFAISCSCLAINRNKQMDVINASWWVMSNSTRHELERSFDCCGLFN---LTMPYLQDDTSCGAMCKTRSSACQMCGEKFLKHSDEALKILGGVGLFFSFTEILGVWLAMRFRNQKDPRANPSAFL", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q7ZUB3-1", "uniprot_id": "TSN31_DANRE", "id": "Q7ZUB3-1", "name": "Tetraspanin-31", "aln": "MVCGGFTCSKNALCSLNVVYMLVGLLLIVVAAWGKGFGIVSSIHIIGGVIAVGFFLQLIAIVGLIGAVHHHQVMLFFYMVILFVVFLFQFGVSCSCLAMNQGQQEKLLESSWKIMSNDTRISLEKKLDCCGLFNSTNLQADIMSDLHLCTSPC-TQKKECVTCGLKMLQHSSEALKILGGVGLFFSFTEILGVWLAMRYRNQKDPRANPSAFL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:*******:********.**** *******:*:**************.** ***:.**:***:****:*****:** :**:*** :******:*:.:* .::::** :***.** .**:.:******* * .* * : * ::. * ** *:*:**.**************************:**************", "identical_positions": 148, "similar_positions": 39, "identity": "69.48%" }, { "cls_id": "homologset.oma.815110", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NG11-1", "uniprot_id": "TSN14_HUMAN", "id": "Q8NG11-1", "name": "Tetraspanin-14", "aln": "----MHYYRYSNAKVSCWYKYLLFSYNIIFW-----------------------------LAGVVFLGVGLWAWSEKGVLSDLTKVTRMHGIDPVVLVLMVGVVMFTLGFAGCVGALRENICLLNFFCGTIVLIFFLELAVAVLAFLFQDWVRDRFREFFESNIKSYRDDIDLQNLIDSLQKANQCCGAYGPEDWDLNVYFNCSG-ASYSREKCGVPFSCCVPDPAQKVVNTQCGYDVR-IQLKSKWDESIFTKGCIQALESWLPRNIYIVAGVFIAISLLQIFGIFLARTLISDIEAVKAGHHF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A3Q1MHM8-1", "uniprot_id": "A0A3Q1MHM8_BOVIN", "id": "A0A3Q1MHM8-1", "name": "Tetraspanin", "aln": "----MHYYRYSNAEVSCWYKYLLFSYNIVFWVLINGGTTPAECTAVEQNNRGLLNFRDHELAGVVFLGVGLWAWSEKGVLSDLTKVTRMHGIDPVVLVLMVGVVMFTLGFAGCVGALRENICLLNFFCSTIVLIFFLELAVAVLAFLFQDWVRDRFREFFESNIRSYRDDIDLQNLIDSLQKANQCCGAYGPEDWDLNVYFNCSG-ASYSREKCGVPFSCCVPDPAQKVVNTQCGYDVR-TQLKSKWDESIFTKGCIQALESWLPRNIYIVAGVFIAISLLQIFGIFLARTLISDIEAVKAGHHF", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "D4A0Z1-1", "uniprot_id": "D4A0Z1_RAT", "id": "D4A0Z1-1", "name": "Tetraspanin", "aln": "----MHYYRYSNAEVSCWYKYLLFSYNIVFW-----------------------------LAGVVFLGVGLWAWSEKGVLSDLTKVTRLHGIDPVVLVLMVGVVMFTLGFAGCVGALRENICLLKFFCGAIVLIFFLELAVAVLAFLFQDWVRDRFREFFESNIRSYRDDIDLQNLIDSLQKANQCCGAYGPEDWDLNVYFNCSG-ASYSREKCGVPFSCCVPDPAQKVVNTQCGYDVR-IQLKSKWDEFIFTKGCIQALEGWLPRNIYIVAGVFIAISLLQIFGIFLARTLISDIEAVKAGHHF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3HQ18-1", "uniprot_id": "G3HQ18_CRIGR", "id": "G3HQ18-1", "name": "Tetraspanin", "aln": "----MHYYRYSNAEVSCWYKYLLFSYNIVFW-----------------------------LAGVVFLGVGLWAWSEKGVLSDLTKVTRLHGIDPVVLVLMVGVVMFTLGFAGCVGALRENICLLKFFCGAIVLIFFLELAVAVLAFLFQDWVRDRFREFFESNIRSYRDDIDLQNLIDSLQKANQCCGAYGPEDWDLNVYFNCSG-ASYSREKCGVPFSCCVPDPAQKVVNTQCGYDVR-IQLKSKWDEFIFTKGCIQALEGWLPRNIYIVAGVFIAISLLQIFGIFLARTLISDIEAVKAGHHF", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q8QZY6-1", "uniprot_id": "TSN14_MOUSE", "id": "Q8QZY6-1", "name": "Tetraspanin-14", "aln": "----MHYYRYSNAEVSCWYKYLLFSYNIVFW-----------------------------LAGVVFLGVGLWAWSEKGVLSDLTKVTRLHGIDPVVLVLMVGVVMFTLGFAGCVGALRENICLLKFFCGAIVLIFFLELAVAVLAFLFQDWVRDRFREFFESNIKSYRDDIDLQNLIDSLQKANQCCGAYGPEDWDLNVYFNCSG-ASYSREKCGVPFSCCVPDPAQKVVNTQCGYDVR-IQLKSKWDEFIFTKGCIQALEGWLPRNIYIVAGVFIAISLLQIFGIFLARTLISDIEAVKAGHHF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58H262-1", "uniprot_id": "A0AC58H262_DANRE", "id": "A0AC58H262-1", "name": "Tetraspanin", "aln": "MNKKMHYYRYENAEVSCCYKYLMFSYNIIFW-----------------------------LAGSAFIAIGFWAWSEKGVLSDLTQVTRLHGFDPVWGVLVVGTVTFILGFAGCVGALRENICLLKFFSGVIGFIFFLELTAAVLAFVFQGQVREWISEFFLANVKAYRDDIDLQNLIDSLQKLNHCCGAKHPNDWNMNVYFNCSNKNNLSREKCGVPFSCCISDPAVTVLNTQCGYDVREKGTLNDWSSSIYIKGCIDALEDWLPRNLYIVAGVFIVISLLQMVGIFLARTLIGDIEKVKFNYY-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******.**:*** ****:*****:** *** .*:.:*:*************:***:**:*** **:**.* * *****************:**...* :******:.*****:**. **: : *** :*:::**************** *:**** *:**::*******. . ************:.*** .*:********* ..*.. *: ****:***.*****:********.*****:.*********.*** ** .:: ", "identical_positions": 190, "similar_positions": 54, "identity": "62.3%" }, { "cls_id": "homologset.oma.815111", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O60636-1", "uniprot_id": "TSN2_HUMAN", "id": "O60636-1", "name": "Tetraspanin-2", "aln": "MGRFRGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLYVLVGAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAYNDYLKDRGKGNGTLITFHSTFQCCGKESSEQ-VQPTCPKELLGHKNCIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNSRDVI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1SAW5-1", "uniprot_id": "F1SAW5_PIG", "id": "F1SAW5-1", "name": "Tetraspanin", "aln": "MGRFRGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGTMKDFSSEDKSPEYFYMGLYVLVGAGVLMMAVGFFGCCGATRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAYNDYLRDREKGNGTLITFHSAFQCCGKESSEQ-VQPTCPKELLGHKNCIDEIETIISVKLQLVGIVGIGIAGLTIFGMIFSMVLCCAIRNSQDVI", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q922J6-1", "uniprot_id": "TSN2_MOUSE", "id": "Q922J6-1", "name": "Tetraspanin-2", "aln": "MGRFRGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGTMKDLSSEDKSPEYFYVGLYVLVGAGALMMTVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKDVAIRHVQSMYEEAYSDYLKDRARGNGTLITFHSAFQCCGKESSEQ-VQPTCPKELPGHKNCIDKIETVISAKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNSRDVI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E1C2R3-1", "uniprot_id": "E1C2R3_CHICK", "id": "E1C2R3-1", "name": "Tetraspanin", "aln": "MGTAYARMRCIKILLFIFNLSFWLAGLAVIAFGLWLRFGGAMAEFASDKRSPEYFFIGLYVLVGAGALMTTVGFFGCCGAARESQFLLGAFFACLLVIFAAEITAGVFAFIGKKVAIQEAQRIYEDIYDEYVKNPGKVNRTIYHYHLALQCCGKDNLEQHVGLPCPEKMQVPKNCLVEIHNVIDANLHLVGIVGIAIAGTTIFGMIFSMVLCCAIRNTREMI", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . :**** **: *** ***** ********:****:: :::*:.:*****::*********.** :********* **** :**:**:*********:*:******** ***:..* :**: *.:*::: : * *: :* ::*****:. ** * .**::: ***: :*..:*..:*:*:*****.*** *****************::::*", "identical_positions": 134, "similar_positions": 57, "identity": "60.36%" }, { "cls_id": "homologset.oma.815114", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R3G9-1", "uniprot_id": "TSN8_MOUSE", "id": "Q8R3G9-1", "name": "Tetraspanin-8", "aln": "MAGVSSCLKYSMFFFNFLFWVCGTLILGLAIWVRVSKDGKEIITSGDSSTNPFIAVNILIAVGSIIMVLGFLGCCGAVKESRCMLLLFFIGLLLILILQVAAGILGAAFKPEYNRILNETLYENAKLLSDNTDEAKDFQKAMIVFQSEFKCCGLENGAADWGNNF---VEAKESCQCTG-----TDCATYQGSSVYPKTCLSLIKDLFEKNIIIVIGIAFGLAVIEI---LGLVFSMVLYCQIGSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O55158-1", "uniprot_id": "O55158_RAT", "id": "O55158-1", "name": "Tetraspanin", "aln": "MAGVSGCLKYSMFFFNFLFWVCGTLILGLAIWLRVSKDGKEIITSGDNGTNPFIAVNILIAVGSIIMVLGFLGCCGAVKESRCMLLLFFIGLLLILLLQVAAGILGATFKSESSRILNETLYENAKLLSETSNEAKEVQKAMIAFQSEFKCCGLRFGAADWGKNF---PDAKESCQCTG-----SDCESYNGENVYRTTCLSLIKELVEKNIIIVIGIAFGLAVIEI---LGLVFSMVLYCQIGSK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19075-1", "uniprot_id": "TSN8_HUMAN", "id": "P19075-1", "name": "Tetraspanin-8", "aln": "MAGVSACIKYSMFTFNFLFWLCGILILALAIWVRVSNDSQAIFGSEDVGSSSYVAVDILIAVGAIIMILGFLGCCGAIKESRCMLLLFFIGLLLILLLQVATGILGAVFKSKSDRIVNETLYENTKLLSATGESEKQFQEAIIVFQEEFKCCGLVNGAADWGNNF---QHYPELCACLDKQ---RPCQSYNGKQVYKETCISFIKDFLAKNLIIVIGISFGLAVIEI---LGLVFSMVLYCQIGNK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1C3Y3-1", "uniprot_id": "E1C3Y3_CHICK", "id": "E1C3Y3-1", "name": "Tetraspanin", "aln": "MAGVSRCLKYSMFIFNFLFWVCGCIILGVSIWIRVNKDAQEALNINN--SNMFVGADVLIAVGSIIMILGFLGCCGAIKESRCMLLLFFIGLLLILILQVTGGILGAVYKPQLEEGFNLVITEAANLLKENTENAKQVQESLQKFQLQGHCCGIVDGITDWGNNYNLVIDGKAVCECERKYQEENLCTYFQGRYVFKEPCKTVILNFLQTNMDIIMGIAFGMAVIEV---LGLVFSMCLYCQIQRK--", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "A0AAA9T0S8-1", "uniprot_id": "A0AAA9T0S8_BOVIN", "id": "A0AAA9T0S8-1", "name": "Tetraspanin", "aln": "MAGVNVCIKCSMFIFNFVFWLCGAIILSVAISIRAGKIGQEILAPGDADLNLFIAVNILIFVGAVIMILGFLGCCGAMKENQFMMILFFVGLLMILLLQVAAGIVATTRKSKTEQALNKTLLINARLLSSTDENERVFQKAFSELQEELKCCGLVNGASDWGSNF---QHYYRTCECPSES--DSSCTKYSGKTIYKQSCFASISQMFSKRLFIVIALAFGLAAIEVQYYLKFLRKLCLRCLHLLSSI", "tax_id": 9913, "tax_name": "Bovine" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****. *:* *** ***:**:** :**.::* :*..: .: : : . ::..::** **::**:*********:**.: *::***:***:**:***: **:.:. *.: .. .* .: :.**. . :. : .*::: :* : :***: * :***.*: . * * * :.* :: .* : * ::. ..: *::.::**:*.**: * :: .: * * . ", "identical_positions": 80, "similar_positions": 90, "identity": "32.26%" }, { "cls_id": "homologset.oma.815469", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFM4-1", "uniprot_id": "D3ZFM4_RAT", "id": "D3ZFM4-1", "name": "Dehydrodolichyl diphosphate synthase complex subunit NUS1", "aln": "MTGLYELVWRVLHLLFCLYRTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKLPAVGRNRRHHRHPHRGPGP----AATHPRLRWRADGRSLQKLPVHMGLVITEEVQEPSFSDIASLVVWCMAVGISYISVYDHQGIFKRNNSRLMDEILKQQQELLGQDCSKYSAEFANS--NDKDDQVLNCPSAVKVLSPEDGKADIVRAAQDFCQSVAQQQRRPTELGVELLDSLLSSH-GFPDPDLVLKFGPVDSTLGFLPWQIRLTEIISLPSHSNISYEDLFSALRQYAACEQRLGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LJ8-1", "uniprot_id": "NGBR_MOUSE", "id": "Q99LJ8-1", "name": "Dehydrodolichyl diphosphate synthase complex subunit Nus1", "aln": "MTGLYELVWRVLHALLCLHLTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKPRAVGRNRRHHRHPHGGPGPGPGPAATHPRLRWRADVRSLQKLPVHMGLLVTEEVQEPSFSDIASLVVWCMAVGISYISVYDHQGIFKRNNSRLMDEILKQQQELLGQDCSKYSAEFANS--NDKDDQDLNCPSAVKVLSPEDGKADIVRAAQDFCQLVAQQQRKPTDLDVDLLGSLLSSH-GFPDPDLVLKFGPVDSTLGFLPWQIRLTEIVSLPSHLNISYEDFFSALRQYAACEQRLGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "I3LLX5-1", "uniprot_id": "I3LLX5_PIG", "id": "I3LLX5-1", "name": "Dehydrodolichyl diphosphate synthase complex subunit NUS1", "aln": "MTGLYELVWRVLHALLCLHRTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKPPAVGRNRRHHRHPRGGSAS----AAAHPRLRWRADCRSLEKLPVHMGLVITEEEQEPSFSDIASLVVWCMAVGISYISVYDHQGIFKRNNSRLMDEILKQQQELLGLDCSKYSPEFSNS--NDKDDQVLNCQSAVKVLSPEDGKADIVRAAQDFCQLVAQQQKKSTDLDVDMLDSLLSSN-GFPDPDLVLKFGPVDSTLGFLPWHIRLTEIVSLPSHLNISYEDFFSALRQYAACEQRLGK", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A3Q1MAW4-1", "uniprot_id": "A0A3Q1MAW4_BOVIN", "id": "A0A3Q1MAW4-1", "name": "Dehydrodolichyl diphosphate synthase complex subunit NUS1", "aln": "MTGLYELVWRVLHALLCLHRTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKPPAVGRNRRHHRHPRGGPAP----AAAHRRLRWRADGRSLEKLPVHMGLVITEEEQEPSFSDIASLVVWCMAVGISYISVYDHQGIFKRNNSRLMDEILKQQQELLGLDCSKYSPEFANS--NDKDDQVLNCQSAVKVLSPEDGKADIVRAAQDFCQLVAQQQKKSTDLDVDMLDSLLSSN-GFPDPDLVLKFGPVDSTLGFLPWHIRLTEIISLPSHLNISYEDFFSALRQYAACEQRLGK", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q96E22-1", "uniprot_id": "NGBR_HUMAN", "id": "Q96E22-1", "name": "Dehydrodolichyl diphosphate synthase complex subunit NUS1", "aln": "MTGLYELVWRVLHALLCLHRTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKPPAVGRNRRHHRHPRGGSCL----AAAHHRMRWRADGRSLEKLPVHMGLVITEVEQEPSFSDIASLVVWCMAVGISYISVYDHQGIFKRNNSRLMDEILKQQQELLGLDCSKYSPEFANS--NDKDDQVLNCHLAVKVLSPEDGKADIVRAAQDFCQLVAQKQKRPTDLDVDTLASLLSSN-GCPDPDLVLKFGPVDSTLGFLPWHIRLTEIVSLPSHLNISYEDFFSALRQYAACEQRLGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1N8Y0-1", "uniprot_id": "F1N8Y0_CHICK", "id": "F1N8Y0-1", "name": "Dehydrodolichyl diphosphate synthase complex subunit NUS1", "aln": "MSAVGGLAWRALHALLRALLCLQRALLA--APRAWLRRR--AAASCALLGPAARALAFPGAARGVRRPGRRRPG------------VRARGRADGRALQKLPLHVGLVVTEE--EPSYADMASLVVWCMAVGISYVSVYDHNGIFKRNNSRLMDEILKQEQELLGLDCSKYTVEFAN---QDKADQVLNCQSTLKVLSPEDGKADIVKAAQNFCQLVAQQQRTYTDLDVNVLDNLLSSTSGFPDPDLVLKFGPVDSTLGFLPWHIRLTEIISLPSHQNISYEDFFSALHRYAACEQRWGK", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q6DHR8-1", "uniprot_id": "NGBR_DANRE", "id": "Q6DHR8-1", "name": "Dehydrodolichyl diphosphate synthase complex subunit nus1", "aln": "MASLYEMVWRFLHALLYLQRAIVAWFRVH------IWRW--KLAVVDLLLPLALGFHNQKKTG--PKGTRTSR--------------RVRWGADGRTLEKLPLHVGLLVTEE--EIHYTDIANLVVWCMAVGISYVSVYDNQGVFKRNNSRLMEEILKQQQELLGMGSSKYSVEILKNGTNKQEHQVLSCQSMVKVLSPDDGRLSIVQAAQQLCRAVEQKEKTSKDINVSVLDSLLKESKNIPDPDLVLKFGTVQSTLGFLPWHIRLTEIISMPSHIDASYDDLYDALQRFAGCEQRLGK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.: :.** ** *: : : . : * * :* * . : . : * * * ** *:*:***:*:**::** * ::*:*.************:****::*:*********:*****:***** ..***: *: : :.: .* *.* :*****:**: .**:***::*: * *::: .::.*. * .**.. . **********.*:********:******:*:*** : **:*::.**:::*.**** **", "identical_positions": 131, "similar_positions": 75, "identity": "43.67%" }, { "cls_id": "homologset.oma.815494", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q96GM8-1", "uniprot_id": "TOE1_HUMAN", "id": "Q96GM8-1", "name": "Target of EGR1 protein 1", "aln": "MAADSDDGAVSAPAASDGGVSKSTTSGEELVVQVPVVDVQSNNFKEMWPSLLLAIKTANFVAVDTELSGLGDRKSLLNQCIEERYKAVCHAARTRSILSLGLACFKRQPDKG----------------------------------------------EHSYLAQVFNLTLLCMEEYVIEPKSVQFLIQHGFNFNQQYAQGIPYHK----------------------------------------------------GNDKGDESQSQSVRTLFLELIRARRPLVLHNGLIDLVFLYQNFYAHLPESLGTFTADLCEMFPAGIYDTKYAAEFHARFVASYLEYAFRKCERENGKQRAA--GSPHLTLEFCNYPSSMRDHIDYR----CCLPPATHR---PHPTSICDNFSAYGWCPLGPQCPQSHDIDLIIDTDEAAAEDKRRRRRRREKRK------RALLNLP---GTQTSGEAKDGPPKKQVCGDSI----KPEETEQEVAADETRNLPHSKQGNKNDLEMGIKAARPEIADRATSEVPGS---------------------------------QASPNPVPGDGLHRAGFDAFMTGYVMAYVE-VSQGPQPCS--SGPWLPECHNKVYLSGKAVPLTVAKSQFSRSSKAHNQKMKLTWGSS---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q17QN2-1", "uniprot_id": "TOE1_BOVIN", "id": "Q17QN2-1", "name": "Target of EGR1 protein 1", "aln": "MAADSDDGAASAPTVSDDGVRQSTKSGEELVVQVPVVDVQSDNFKEMWPSLLLAIKTANFVAVDTELSGLGDRKCLLNQCIEERYKAVCHAARTRSILSLGLACFKQQPDKG----------------------------------------------EHSYLAQVFNLTLLCMEEYVIEPKSVQFLVQHGFNFNRQYAQGIPYHK----------------------------------------------------GNDKGDESQRQSVRTLFLELIRARRPLVLHNGLIDLVFLYQNFYAHLPENLGTFTADLCEMFPAGIYDTKYAAEFHARFLASYLEYAFRKCERENGKQRAA--GSPHLTLEFCSYPSSMRAHIDYR----CCAPPPTYR---THSTSICDNFSAYGWCPLGPQCPRSHDIDLIIDTDEAALEDKRRRRRRKEKRR------RALLGLP---GKQPSREAEDSPPTKQVCKDNR----KPEETEQEVAEDETGTQPGSEQGHTNDLEMEPKATSAETTDTATSEAPERQ-------------------VTTDMATSEAPERQVSPNPVPGDGLHRAGFDAFMTGYVMAYVG-VSQGSHPCS--SEPWLPECHNKVYLSGKAVPLTVVKSQFSRSSKAHNQKMKLAWGSS---------", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A0G2JZE8-1", "uniprot_id": "A0A0G2JZE8_RAT", "id": "A0A0G2JZE8-1", "name": "Target of EGR1 protein 1", "aln": "MAADSDDGVPSVPTPSDGGVNRTTQSAEEFVVRVPVVDVQSDNFKEIWPSLLLALKTASFVAVDTELSGLGDRKSLLNQCIEERYKAVCHAARTRSVLSLGLACFKQQPDKG----------------------------------------------DSSYLAQVFNLTLLCMEEYVIEPKSVQFLVQHGFNFNRQYAQGIPYHK----------------------------------------------------GNDKGDESQSQSVRTLFLELIRARRPLVLHNGLIDLVFLYQNFYAHLPENLGTFTADLCEMFPAGIYDTKYAAEFHARFVASYLEYAFRKCERENGKQRAA--GSPHVALEFCSYPSSMRGHIDYR----CCMSPVSCRH--SHTTGICDKFSAYGWCPLGPQCPQSHDIDLIIDTDEAVAEDKRRRRRRKDKRK------RALQSQP---ETQTLEEAEDGPPTKQVCEDSL----KTEKIEQKVAE---GDQLGSTQGHKDSLEMACKR----TADVPTSELLVN---------------------------------QASPNPVPGDGLHRAGFDAFMTGYVMAYVG-LSKGLQLCS--SEPWLPECHNKVYLSGKTVPLTVAKSQFSRPSKAHNQKMKLAWGSS---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D2E2-1", "uniprot_id": "TOE1_MOUSE", "id": "Q9D2E2-1", "name": "Target of EGR1 protein 1", "aln": "MAADSDDDVPPVPTPSDGGVNKNTQPAEEFVVRVPVVDVQSDNFKEIWPSLLLALKTASFVAVDTELSGLGDRKSLLNQCIEERYKAVCHAARTRSVLSLGLACFRQQPDKG----------------------------------------------ENSYLAQVFNLTLLCIEEYVIEPKSVQFLVQHGFNFNRQYAQGIPYHK----------------------------------------------------GNDKGDESQSQSVRTLFLELIRARRPLVLHNGLIDLVFLYQNFYAHLPENLGTFTADLCEMFPAGIYDTKYAAEFHARFVASYLEYAFRKCERENGKQRAA--GSPHLALEFCSYPSSMSGHIDYR----CCMSPGTCRR--SRTTGICDKFSAYGWCPLGPQCPQSHDIDLIIDTDEAVAEDKRRRRRRKDKRK------RSLQSQP---GTQTLAEAEDGPPTKQVCEDSL----ETEKMEQKVAEGEAGDQPGSREGHTSSLEMAHRRTSAETADVATSELLVN---------------------------------QASTNPVPGDGLHRAGFDAFMTGYVMAYVG-LSQGLQLCS--SEPWLPECHNKVYLSGKTVPLTVTKSQFSRPSKAHNQKMKLAWGSS---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1N9P8-1", "uniprot_id": "F1N9P8_CHICK", "id": "F1N9P8-1", "name": "Target of EGR1 protein 1", "aln": "MARG----------------------------QVPVVDVQSDNFTELWPSMVLALRTATFIAVDTELSGLGARKALLSPCIDERYKAVCNAARTRSVLSLGIACFKQLPEKS----------------------------------------------ENTFLCQIYNLTLLCTEDYIVEPQSVQFLVQHGFDFNKQYSQGIPYHK----------------------------------------------------GNDKGNESQSQSVRTFFLELIRAKKPLILHNGLIDLVFLYQCFYAHLPDSLGTFTSDLSEMFPAGIYDTKYASEFETRFVASYLEYAYKKCKRENGKLKDS--SSQHISVEFCSYPANMSRYIDYRH---CSLEEASHSEGEANKVPVCEKFSAYGWCPNGVKCPQSHNIDLIIDEDDKLCEKAKKRKHRRKRRKNAEEPEKALEQESSGKEMELIQNGEEEPPRKQSCYEPANADGRPREEENSTAMEPEGSSDTSTHGGRQGEDLRSAEETAALSPSAKANAHDNDQVEGNSEVFARTVSTNHPDVPETEAACAAGKQNASQGPSSQVGTHRAGFDAFMTGYVMAYVW-MLKKRKSTDTEAEPWCPDCHNKLYLSGKSVPLQIVKSSFSKSSAAHNQKMKLVWATG---------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "B8A5U4-1", "uniprot_id": "B8A5U4_DANRE", "id": "B8A5U4-1", "name": "Target of EGR1 protein 1", "aln": "MSSS---------------------------MIIPVIDVQGNNFKELWAAMVIAIKTSSFIAIDTELSGLGSRKALLAESIEDRYNAICHAARTRSVLSLGFACYKELENKA----------------------------------------------ETTYLVQVYNLTLLCSEEYIIEPQSVQFLVQHGFDFNKQYAEGIPYYK----------------------------------------------------GNDKGGDAHGVNIRSLFVELLRANKPLVLHNGLIDLVFLYQCFYAHLPDRLGTFTADLSQMFPSGIYDTKYATEYELRFTASYLEYAYKKCKLENSKAIEAEGSGSNLFVEFCKYTGNMETYIDYR----PCLDSQSQDD---GALNICVQFSAYGWCPNGSQCPMSHNTDLIIQQDEKTREDKRKKRKRKNKKK----------------GSQGPPETCSSPQGKRTHFEEA-------ELDQAVPTSEHQEKTLNAEPTDEPGKTASNNGDEQSQPEASTEAQEK-----------------------------------PKGKKVEGGTHRAGFDAFMTGYIFAYARNLMKNKEESS--STPVISTCLNKLFLSGKSVPLHVAKSTFSKSSKAHVQKMAYVWGKSIDVNMEKSA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86I34-1", "uniprot_id": "Q86I34_DICDI", "id": "Q86I34-1", "name": "C3H1-type domain-containing protein", "aln": "MNQTHN------IHDSDDNNKKNILTTTKTKTTTLVKRVTLKNFDKEIINFENDLKEATFISIDTEFTGLGFQKGLKQEDIQEKYHAMINLVKQRSILEFGISIFKANFKDDKEEENNTSSSGSGDYNPNNTKEEDVGEVVTPPTNYNNSIDDNHSLLEKSYTIRVYNFIMLNISDFQVSPVSMTFLSKHGFDFQELFLYGIPFQSRRPIFSTPTKNNNSYNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNHEDTLRRSKLLLDILTKAQLPSVIHNGIFDLLFIFQSLIGDLPDKLNDFISKILSVFPK-IYDTKYIAEYKVSEKRSYLQYLFQKYERFNFKRLLR--KEVYATCDFKAFSDNDSDDGDDNILIPLINTEYSFIKPISPNIKVCNDFADYGHCRLKDNCPDSHDISLVLDLEEHKSQKKKRSRNKLESNE-----------------DEKLNEEQEIKKTE----------------GENIVSIVNNSIIENEDDNNNNNNNNNNNNNNNNNNNKYKELFKME----------------------------------------GQNVHSAGFDSALTGFIFVYYLLLFKNSNLQN--------EVENKIFLSGKQVPLVLKVSKYA--------------------------", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * * .** : : :: :.*:::***::*** :* * *:::*:*: : .: **:*.:*:: :: .. : :: :::*: :* .:: :.* *: ** :***:*:. : ***: . .*::. : : :: * :*. * ::***::**:*::* : ..**: *. * :.: .:** ****** :*:. ***:* ::* : * * :* :. . * . : :* .*: ** * :** **: .*::: :: :. :: :.: . .. : : . : : . . . . : . * ****: :**:::.* : : . . **::**** *** : * :: ", "identical_positions": 95, "similar_positions": 138, "identity": "14.07%" }, { "cls_id": "homologset.oma.815502", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q14442-1", "uniprot_id": "PIGH_HUMAN", "id": "Q14442-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit H", "aln": "----------MEDERSFSDICGGRLALQRRYYSPSCREFCLSCPRLSLRSLTAVTCTVWLAAYGLFTLCENSMILSAAIFITLLGLLGYLHFVKIDQETLLIIDSLGIQMTSSYASGKESTTFIEMGKVKDIVINEAIYMQKVIYYLCILLKDPVEPHGISQVVPVFQSAKPRLDCLIEVYRSCQEILAHQKATSTSP---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1MGP1-1", "uniprot_id": "F1MGP1_BOVIN", "id": "F1MGP1-1", "name": "", "aln": "MAGPGAGEPAMEDERSFSDICGGRLALHRRYYSPSCLEFCLSCPRISLRSLTAVTCTVWLAAYGLFTLCENSMILSAAIFITLLGLLGYLHFVKIDHETLLIIDSLGIQMTSSYASGKESTTFIEMGKVKDVIINEAIYMQKVIYYLCILLKDPVEPHGISQVVPIFQSAKPRLDCLIEVYRSCQEILAHQKAASTSP---", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q5M9N4-1", "uniprot_id": "PIGH_MOUSE", "id": "Q5M9N4-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit H", "aln": "----------MEDEKSFSDICGGRLALRCRYYSPYCREFGLSSARLSLCSLTAVTCAVWLAAYGLFTLCENSMVLSATIFITILGLLGYLHFVKIDQETLLIIDSLGIQMTSSYASGKESTTFIEMDKVKDIIINEAIYMQKVIYYLCILLKEPGKPHEISRVVPVFQSAKPRLDCLIEVYRSCQEVLAHQKATATSL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A0Z0-1", "uniprot_id": "D4A0Z0_RAT", "id": "D4A0Z0-1", "name": "", "aln": "----------MEDEKSFSDICGGRLALRRRYYSPYCREFGLSSARLSLWSLTAVTCTVWLAAYGLFTLCENSMILSAAIFITILGLLGYLHFVKIDQETLLIIDSLGIQMTSSYASGKESTTFIEMNKVKDIIINEAIYMQKVIYYLCILLKDPGKPHEISQVVPVFQSAKPRLDCLIEIYRSCQEILAHQKATPTSL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3H1L9-1", "uniprot_id": "G3H1L9_CRIGR", "id": "G3H1L9-1", "name": "", "aln": "----------MEEEKSFSDICGGRLALRRRYYSPYCREFGLSSPRLSLRSLTAVTCAVWLVAYGLFTLCENSMILSAAIFITIIGLLGYLHFVKIDQETLLIIDSLGIQMTSSYASGKESTTFIEMDKVKDVIINEAIYMQKVIYYLCILLKDPGKPHEISQVVPVFQSAKPRLDCLIEVYRSCQEILAHQKATSTSP---", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "F1P5E0-1", "uniprot_id": "F1P5E0_CHICK", "id": "F1P5E0-1", "name": "", "aln": "----------ME-ERRYRSASGAPLALRCRQHSASCRELAVRCPRLQLRSLSAVTSAVWLAAYGLFVLCQNSMVLSAAIFLTLIGLIIYLHFVKIDQESLLVIGSLGIQVTSSYASGKESTTFIEMSQVKDVVINEAIHMQKVIYYLCILLQDPQDPQGVSEVVPLFQSSQPRLDCLIEVYKSCHEILDQRKAASQSDGVK", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** *: : . .*. ***: * :*. * *: : ..*:.* **:***.:***.*****.**:***:***:**:*::**: ********:*:**:*.*****:****************.:***::*****:************::* .*: :*.***:***::********:*:**:*:* ::**:. * ", "identical_positions": 117, "similar_positions": 53, "identity": "58.21%" }, { "cls_id": "homologset.oma.815527", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P37108-1", "uniprot_id": "SRP14_HUMAN", "id": "P37108-1", "name": "Signal recognition particle 14 kDa protein", "aln": "MVLLESEQFLTELTRLFQKCRTSGSVYITLKKYDGRTKPIPKKGTVEGFEPADNKCLLRATDGKKKISTVVSSKEVNKFQMAYSNLLRANMDGLKKRDKKNKTKKTKAAAAAAAAAPAAAATAPTTAATTAATAAQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6QQL9-1", "uniprot_id": "SRP14_BOVIN", "id": "A6QQL9-1", "name": "Signal recognition particle 14 kDa protein", "aln": "MVLLESEQFLTELTRLFQKCRLSGSVFITLKKYDGRTKPIPRKGSVEGFEPSDNKCLLRATDGKKKISTVVSSKEVNKFQMAYSNLLRANMDGLKKRDKKSKSKKSKAAQ--------------------------", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "P16254-1", "uniprot_id": "SRP14_MOUSE", "id": "P16254-1", "name": "Signal recognition particle 14 kDa protein", "aln": "MVLLESEQFLTELTRLFQKCRSSGSVFITLKKYDGRTKPIPRKSSVEGLEPAENKCLLRATDGKRKISTVVSSKEVNKFQMAYSNLLRANMDGLKKRDKKNKSKKSKPAQ--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8C2N8M7-1", "uniprot_id": "A0A8C2N8M7_CRIGR", "id": "A0A8C2N8M7-1", "name": "Signal recognition particle 14 kDa protein", "aln": "MVLLESEQFLTELTRLFQKCRSSGSVYITLKKYDGRTKPTPRKSAVESVEPAENKCLLRATDGKRKISTVVSSKEVNKFQMAYSNLLRANMDGLKKRDKKNKSKKTKPAQ--------------------------", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "O04421-1", "uniprot_id": "SRP14_ARATH", "id": "O04421-1", "name": "Signal recognition particle 14 kDa protein", "aln": "MVLLQLDPFLNELTSMFEKSKEKGSVWVTLKRSSLKSKVQKRKLSSVG-ESIEYRCLIRATDGKKTVSTSVGAKDHQRFQASYATILKAHMTALKKRERKDRKKSTEAEKKESTSTTKSKKL--------------", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q9VDL0-1", "uniprot_id": "Q9VDL0_DROME", "id": "Q9VDL0-1", "name": "Signal recognition particle 14 kDa protein", "aln": "MVLLDNSNFILRLEKIANAAKKDSSFTLTFKRYDGNDKPVPREGRPPLPKPETYMCLMRAQSKSQKISTVVRQEDVPAMMSMYSQFMKSKMDGLKRVKKVKSKAKATKG---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****: . *: .* : : .: ..*. :*:*: . . * :: :. **:** . .:.:** * :: : *: :::::* .**: .: . . .: ", "identical_positions": 21, "similar_positions": 43, "identity": "15.44%" }, { "cls_id": "homologset.oma.815542", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LGW6-1", "uniprot_id": "A0ABK0LGW6_RAT", "id": "A0ABK0LGW6-1", "name": "HEAT repeat-containing protein 5B", "aln": "----------------------------------------MCEVRTSIMELAHSLLLNEEALAQITEAKR--PVFIFEWLRFLDKVLVAANKTDVKEKQKKLVEQLTGLISSSPGPPTRKLLAKNLAALYSIGDTYTVFQTLDKCNDIIRSKDDTAAYLPTKLAAVACVGAFYEKMGRMLGSAFPETVNNLLKSLKSAESQGRSEILMSLRKVLTGLG-GAAASSHRDIYKNAR-SLLTDRSMAVRCAVAKCLLELQNEA-VFMWTAELENIATLCFKALENSNYGVRVAVSKLLGTVMATALMPKQATVMRQN--------------VKRATFDEVLELMATGFLRGGSGFLKSGGEMLKVGGSVNREVRVGVTQAYVVFVTTLGGQWLERSFATFLSHVLDLVSHPRATQTHVDAVYSRRCVSFILRATVGSLLGEKAQIAAAKEICQAIGKQMKAVEAVVNDTSSENKSGAADIAASQHVMVCALQELGSLVQSLNATASPLIQEASIGLLEIVTSVLLHPSMAARLAAAWCLRCVAVALPFQLTPFLDRC-AERLNNLKTSPEAVSGYSFAMAALLGGVHQCPLGIPHAKGKMVVSIAEDLLRTAAQNSRLSLQRTQAGWLLLGALMTLGP-SVVRYHLPKMLLLWRNVFPRSLKELEAEKARGDSFTWQVTLEGRAGALCAMRSFVAHCPELLTEDAVRKLMTPIECAMTMMSHIPSVIKAHGAHLKASAAMVRLRLYDILALLPPKTYEGSFNALLRELVAEFTLTDNSANTTTSLLRSLCHYDDSVLLGSWLQETDHKSIEDQLQPN-----------SASGSGALEHDPSSIY-------------------------------LRIPAGEAVPGPLPLGVSVIDASVALFGVVFPHVSYKHRLQMLDHFAECVKQAKGVRQQAVQLN-IFTAVLSALKGLAENKSTLGPEEVRKSALTLVMGALDN--PNPILRCAAGEALGRMAQVVGEASFIARMAQYSFDKLKSARDVVSRTGHSLALGCLHRYVGGIGSGQHLKTSVSILLALAQDGTSPEVQTWSLHSLALIVDSSGPMYRGYVEPTLSLVLTLLLTVPPSHTEVHQCLGRCLGAIITTVGPELQGNAATISTIRSSCLVGCAITQDHSDSLVQAAAISCLQQLHMFAPRHVNLSSLVPSLCVHLCSSHLLLRRAAVACLRQLAQREAAEVCEYAMSLAKNAGDKEISGGNVSPFAPGVSSRSDIHCRHQGVNITDTGLEGLLFGMLDRETDRKLCSDIHDTLGHMLSSLAVEKLSHWLTLCKDVLAASSDMSAATLLSSGK----------DEESEKKDEMDDDAMFTTLGEEDKSKP--FVAPRWATRVFAADCLCRIINLCENADQAHFDLALAR-SAKLRNPKNDLLVLHLSDLIRMAFMAATDHSNQLRMAGLQALEDIIKKFASVPEPEFPGHVILEQYQANVGAALRPAFSQDTPSDIIAKACQVCSTWIGSGVVS-DLNDLRRVHNLLVSSLDKVQAGKGSPSQLYRES---ATTMEKLAVLKAWAEVYVVAMNIKKEAESKPKRAMKNTD-----DDDDDFGTIDELPPDSLITLVQ--------------------PELPTLSRLWLAALKDYALLTLPAEFSSQLPPDGGAFYTPETIDTARLHYRNSWAPILHAVALWLNSTGFTCQESTEATAVSG-----------------------GQKRSPAVSLNQVPGAMASAKPLPEVNKDRMHLILGVSIQFLCSPRPEEP-------------IEHVTACLQALHTLLGSPYAR-------IHIAEDQLIGVELLSVLHRLLLTWNPPSIQLLVTGVVQQIVRAAQDYLQEKRSALNEEDM-EKESCPALGEGGDTGG-----------------------------------LIPGKSLVFATMELLMFILVRHMPHLSTK---------------MSDSPSHVATKTHLSEESARLVAATVTILSDLPSLCSPAGCMTILPTILFLIARILKDTAIKSVDNHVSPP----VSAALQGIKSIVTLSMAKTEE-TQKQWTALIRSTLACILEYSQ--PDDCMPAPDEVSTLTAIALFLWSASSEIIGVQSLQNGCMNRFKSALNSCDPWVQAKCYQLLLSVFQHSNRALSTPYIHSLAPLVVGKLKAVERDRPASSTELLAVQEGIKVLETLVALGEEQNR---------------------VQLLALLVPTLIS--YLLDENSFASASSISKDLHEFALQNLMHIGPLYPHAFKTVMGAAPELKARLETAVRASQAS-----------------------------KAKAAARQPAPATHSAPTIKLKTSFF-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C547-1", "uniprot_id": "HTR5B_MOUSE", "id": "Q8C547-1", "name": "HEAT repeat-containing protein 5B", "aln": "------------------------------------------------MELAHSLLLNEEALAQITEAKR--PVFIFEWLRFLDKVLVAANKTDVKEKQKKLVEQLTGLISSSPGPPTRKLLAKNLAALYSIGDTYTVFQTLDKCNDIIRSKDDTAAYLPTKLAAVACVGAFYEKMGRMLGSAFPETVNNLLKSLKSAESQGRSEILMSLQKVLTGLG-GAAASSHRDIYKNAR-SLLTDRSMAVRCAVAKCLLELQNEA-VFMWTAELENVATLCFKALENSNYGVRVAVSKLLGTVMATALMPKQATVMRQN--------------VKRATFDEVLELMATGFLRGGSGFLKSGGEMLKVGGSVNREVRVGVTQAYVVFVTTLGGQWLERSFATFLSHVLDLVSHPRATQTHVDAVYSRRCVSFMLRATVGSLLGEKAQIAAAKEICQAIGKQMKAVEAVVNDTSSENKSGTADIAASQHVMVCALQELGSLVQSLNATASPLIQEASIGLLEIVTSVLLHPSMAARLAAAWCLRCVAVALPFQLTPFLDRC-AERLNNLKTSPEAVSGYSFAMAALLGGVHQCPLGIPHAKGKMVVSIAEDLLRTAAQNSRLSLQRTQAGWLLLGALMTLGP-SVVRYHLPKMLLLWRNVFPRSLKELEAEKARGDSFTWQVTLEGRAGALCAMRSFVAHCPELLTEDAIRKLMTPIECAMTMMSHIPSVIKAHGAHLKASAAMVRLRLYDILALLPPKTYEGSFNALLRELVAEFTLTDNSANTTTSLLRSLCHYDDSVLLGSWLQETDHKSIEDQLQPN-----------SASGSGALEHDPSSIY-------------------------------LRIPAGEAVPGPLPLGVSVIDASVALFGVVFPHVSYKHRLQMLDHFAECVKQAKGVRQQAVQLN-IFTAVLSALKGLAENKSTLGPEEVRKSALTLVMGALDN--PNPILRCAAGEALGRMAQVVGEASFIARMAQYSFDKLKSARDVVSRTGHSLALGCLHRYVGGIGSGQHLKTSVSILLALAQDGTSPEVQTWSLHSLALIVDSSGPMYRGYVEPTLSLVLTLLLTVPPSHTEVHQCLGRCLGAIITTVGPELQGNAATISTIRSSCLVGCAITQDHSDSLVQAAAISCLQQLHMFAPRHVNLSSLVPSLCVHLCSSHLLLRRAAVACLRQLAQREAAEVCEYAMSLAKNAGDKEISGGNVNPFTPGVSSRSDVHCRHQGVNITDTGLEGLLFGMLDRETDRKLCSDIHDTLGHMLSSLAVEKLSHWLMLCKDVLAASSDMSAATLLSSGK----------DEESEKKDEMDDDAMFTTLGEEDKSKP--FVAPRWATRVFAADCLCRIINLCENSDQAHFDLALAR-SAKLRNPKNDLLVLHLSDLIRMAFMAATDHSNQLRMAGLQALEDIIKKFASVPEPEFPGHVILEQYQANVGAALRPAFSQDTPSDIIAKACQVCSTWIGSGVVS-DLNDLRRVHNLLVSSLDTVQAGKGSSSQLYRES---ATTMEKLAVLKAWAEVYVVAMNIKKEAESKPKRAMNNPD-----DDDDDYGTIDELPPDSLITLVQ--------------------PELPTLSRLWLAALKDYALLTLPAEFSSQLPPDGGAFYTPETIDTARLHYRNSWAPILHAVALWLNSTGFISQESTEATTVSG-----------------------VQKRSPAVSLNQVPGAMASAKPLPEVNKDRMHLILGVSIQFLCSPRPEEP-------------IEHVTACLQALHTLLGSPYAR-------IHIAEDQLIGVELLSVLHRLLLTWNPPSIQLLVTGVVQQIVRAAQDYLQEKRNALNEEDM-EKESCPTLGEGGDTGG-----------------------------------LIPGKSLVFATMELLMFILVRHMPHLSTK---------------MLDSPSHTAMKTQLSEESARLVAATVAILSDLPSLCSPAGCMTILPTILFLIARILKDTAIKSADNQVPPP----VSAALQGIKSIVTLSMAKTED-TQKQWTTLIRSTLACILEYSQ--PDDCMPAPDEVSTLTAIALFLWSASSEIIGVQSLQNGCMNRFKSALNSCDPWVQAKCYQLLLSVFQHSNRALSTPYIHSLAPLVVGKLKAVERHRPASSTELLAVQEGIKVLETLVALGEEQNR---------------------VQLLALLVPTLIS--YLLDENSFASASSISKDLHEFALQNLMHIGPLYPHAFKTVMGAAPELKARLETAVRASQAS-----------------------------KAKAAARQPAPTTHSTPTIKLKTSFF-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8C2LNN2-1", "uniprot_id": "A0A8C2LNN2_CRIGR", "id": "A0A8C2LNN2-1", "name": "HEAT repeat-containing protein 5B", "aln": "------------------------------------------------MELAHSLLLNEEALAQITEAKR--PVFIFEWLRFLDKVLVAANKTDVKEKQKKLVEQLTGLISSSPGPPTRKLLAKNLAALYSIGDTYTVFQTLDKCNDIIRSKDDTAAYLPTKLAAVACVGAFYEKMGRMLGSAFPETVNNLLKSLKSAESQGRSEILMSLQKVLTGLG-GAAASCHRDIYKNAR-SLLTDRSMAVRCAVAKCLLELQNEA-VFMWTAELENIATLCFKALENSNYGVRVAVSKLLGTVMATALMPKQATVMRQN--------------VKRATFDEVLELMATGFLRGGSGFLKSGGEMLKVGGSVNREVRVGVTQAYVVFVTALGGQWLERSFATFLSHVLDLVSHPRATQTHVDAVYSRRCVSFILRATVGSLLGEKAQIAAAKEICQAIGKQMKAVEAVVNDTSSENKSGAADIAASQHVMVCALQELGSLVQSLNATASPLIQEASIGLLEIVTSVLLHPSMAARLAAAWCLRCVAVALPFQVTPFLDRC-AERLNNLKTSPEAVSGYSFAMAALLGGVHQCPLGIPHAKGKMVVSIAEDLLRTAAQNSRLSLQRTQAGWLLLGALMTLGP-SVVRYHLPKMLLLWRNVFPRSLKELEAEKARGDSFTWQVTLEGRAGALCAMRSFVAHCPELLTEDAIRKLMTPIECAMTMMSHIPSVIKAHGAHLKASAAMVRLRLYDILALLPPKTYEGSFNALLRELVAEFTLTDNSANTTTSLLRSLCHYDDSVLLGSWLQETDHKSIEDQLQPN-----------SASGSGALEHDPSSIY-------------------------------LRIPAGEAVPGPLPLGVSVIDASVALFGVVFPHVSYKHRLQMLDHFAECVKQAKGVRQQAVQLN-IFTAVLSALKGLAENKSTLGPEEVRKSALTLVMGALDN--PNPILRCAAGEALGRMAQVVGEASFIARMAQYSFDKLKSARDVVSRTGHSLALGCLHRYVGGIGSGQHLKTSVSILLALAQDGTSPEVQTWSLHSLALIVDSSGPMYRGYVEPTLSLVLTLLLTVPPSHTEVHQCLGRCLGAIITTVGPELQGNAATISTIRSSCLVGCAITQDHSDSLVQAAAISCLQQLHMFAPRHVNLSSLVPSLCVHLCSSHLLLRRAAVACLRQLAQREAAEVCEYAMSLAKNAGDKESGGANVSPFLPGVSHRGDIHCRHQGVNITDTGLEGLLFGMLDRETDRKLCSDIHDTLGHMLSSLAVEKLSHWLMLCKDVLAASSDMSTATLLSSGK----------DEESEKKDEMDDDTMFTTLGEEDKSKP--FVAPRWATRVFAADCLCRIINLCENSDQAHFDLAMAR-SAKLRNPKNDLLVLHLSDLIRMAFMAATDHSNQLRMAGLQALEDIIKKFASVPEPEFPGHVILEQYQANVGAALRPAFSQDTPSDIIAKACQVCSTWIGSGVVS-DLNDLRRVHNLLVSSLDKVQAGKGSSSQLYRES---ATTMEKLAVLKAWAEVYVVAMNIKKEAESKPKRAMRTPD-----DDDDDYGTIDELPPDSLITLVQ--------------------PELPTLSRLWLAALKDYALLTLPAEFSSQLPPDGGAFYTPETIDTARLHYRNSWAPILHAVALWLNSTGFTCPESTEAAAVSG-----------------------TQKRSLAVGLNQVPGAMASAKPLPEVNKGRMHLILGVSIQFLCSPRPEEP-------------IEHVTACLQALHTLLGSPYAR-------IHIAEDQLIGVELLSVLHRLLLTWNPPSIQLLVTGVVQQIVGAAQDHLQEKRNTINEEDM-EKESCPTLGEGGDSGG-----------------------------------LIPGKSLVFSTMELLMFILVRHMPHLSTK---------------MSDSPSHGTTKTRLSEESARLVAATVAILSDLPSLCSPAGCMTILPTILFLIARILKDTAIKSADNQVPPP----VSAALQGIKSIVTLSMAKTKE-TQKQWTSLIRSTLACILEYSQ--PDDSMPAPDEVSTLTAIALFLWSASSEIIGVQSLQNGCMNRFKSALNSCDPWVQAKCYQLLLSVFQHANRALSTPYIHSLAPLVVEKLKAVERNRPASSTELLAVQEGIKVLETLVALGEDQNR---------------------VQLLALLVPTLIS--YLLDENSFASASSVSKDLHEFALQNLMHIGPLYPHAFKTVMGAAPELKVRLETAVRASQAS-----------------------------QAKAAARQPAPATHSAPTIKLKTSFF-----------------------------------------------", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q9P2D3-1", "uniprot_id": "HTR5B_HUMAN", "id": "Q9P2D3-1", "name": "HEAT repeat-containing protein 5B", "aln": "------------------------------------------------MELAHSLLLNEEALAQITEAKR--PVFIFEWLRFLDKVLVAANKTDVKEKQKKLVEQLTGLISSSPGPPTRKLLAKNLAALYSIGDTFTVFQTLDKCNDIIRNKDDTAAYLPTKLAAVACVGAFYEKMGRMLGSAFPETVNNLLKSLKSAESQGRSEILMSLQKVLSGLG-GAAASSHRDIYKNAR-SLLTDRSMAVRCAVAKCLLELQNEA-VFMWTAELENIATLCFKALENSNYGVRVAVSKLLGTVMATALMPKQATVMRQN--------------VKRATFDEVLELMATGFLRGGSGFLKSGGEMLKVGGSVNREVRVGVTQAYVVFVTTLGGQWLERSFATFLSHVLDLVSHPRATQTHVEAVYSRRCVSFILRATVGSLLGEKAQIAAAKEICQAIGKQMKAVEAVVNDTSGENKSGAADIAASQHVMVCALQELGSLVQSLNATASPLIQEASIGLLEIVTSVLLHPSMAARLAAAWCLRCVAVALPFQLTPFLDRC-AERLNNLKTSPEAVSGYSFAMAALLGGVHQCPLGIPHAKGKMVVSIAEDLLRTAAQNSRLSLQRTQAGWLLLGALMTLGP-SVVRYHLPKMLLLWRNVFPRSLKELEAEKARGDSFTWQVTLEGRAGALCAMRSFVAHCPELLTEDVIRKLMTPIECAMTMMSHIPSVMKAHGAHLKASAAMVRLRLYDILALLPPKTYEGSFNALLRELVAEFTLTDNSANTTTSLLRSLCHYDDSVLLGSWLQETDHKSIEDQLQPN-----------SASGSGALEHDPSSIY-------------------------------LRIPAGEAVPGPLPLGVSVIDASVALFGVVFPHVSYKHRLQMLDHFAECVKQAKGVRQQAVQLN-IFTAVLSALKGLAENKSTLGPEEVRKSALTLVMGPLDN--PNPILRCAAGEALGRMAQVVGEATFIARMAQYSFDKLKSARDVVSRTGHSLALGCLHRYVGGIGSGQHLKTSVSILLALAQDGTSPEVQTWSLHSLALIVDSSGPMYRGYVEPTLSLVLTLLLTVPPSHTEVHQCLGRCLGAIITTVGPELQGNGATTSTIRSSCLVGCAITQDHSDSLVQAAAISCLQQLHMFAPRHVNLSSLVPSLCVHLCSSHLLLRRAAVACLRQLAQREAAEVCEYAMSLAKNTGDKESSSANVSPFAPGVSSRTDIHCRHQGVNITETGLEGLLFGMLDRETDRKLCSDIHDTLGHMLSSLAVEKLSHWLMLCKDVLAASSDMSTATLLSSGK----------DEEAEKKDEMDDDTMFTTLGEEDKSKP--FVAPRWATRVFAADCLCRIINLCENADQAHFDLALAR-SAKLRNPTNDLLVLHLSDLIRMAFMAATDHSNQLRMAGLQALEDIIKKFASVPEPEFPGHVILEQYQANVGAALRPAFSQDTPSDIIAKACQVCSTWIGSGVVS-DLNDLRRVHNLLVSSLDKVQAGKGSSSQLYRES---ATTMEKLAVLKAWAEVYVVAMNIKKEAESKPKRAIKNTD-----DDDDDCGTIDELPPDSLITLVQ--------------------PELPTLSRLWLAALKDYALLTLPAEFSSQLPPDGGAFYTPETIDTARLHYRNSWAPILHAVALWLNSTGFTCSESTEAAAISG-----------------------LQKRSTSVNLNQASGAVGSAKSLPEINKDRMHLILGVSIQFLCSPRPEEP-------------IEHVTACLQALHTLLDSPYAR-------VHIAEDQLIGVELLSVLHRLLLTWNPSSVQLLVTGVVQQIVRAAQDYLQEKRNTLNEDDM-EKEACTVLGEGGDSGG-----------------------------------LIPGKSLVFATMELLMFILVRHMPHLSTK---------------VSDSPSHIATKTRLSEESARLVAATVTILSDLPSLCSPAGCMTILPTILFLIARILKDTAIKSADNQVPPP----VSAALQGIKSIVTLSMAKTEAGVQKQWTALIRSTLACILEYSQ--PEDSVPTPDEVSMLTAIALFLWSASNEIIGVQSLQNGCMNRFKNALNSCDPWVQAKCYQLLLSVFQHSNRALSTPYIHSLAPIVVEKLKAVERNRPASNIELLAVQEGIKVLETLVALGEEQNR---------------------VQLLALLVPTLIS--YLLDENSFASASSASKDLHEFALQNLMHIGPLYPHAFKTVMGAAPELKVRLETAVRASQAS-----------------------------KAKAAARQPAPAIHSAPTIKLKTSFF-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1BB26-1", "uniprot_id": "E1BB26_BOVIN", "id": "E1BB26-1", "name": "HEAT repeat-containing protein 5B", "aln": "------------------------------------------------MELAHSLLLNEEALAQITEAKR--PVFIFEWLRFLDKVLVAANKTDVKEKQKKLVEQLTGLISSSPGPPTRKLLAKNLAALYSIGDTFTVFQTLDKCNDIIRNKDDTAAYLPTKLAAVACVGAFYEKMGRMLGSAFPETVNNLLKSLKSAESQGRSEILMSLQKVLNGLG-GAAASCHRDIYKNAR-SLLTDRSMAVRCAVAKCLLELQNEA-VFMWTAELENIATLCFKALENSNYGVRVAVSKLLGTVMATALMPKQATVMRQN--------------VKRATFDEVLELMATGFLRGGSGFLKSGGEMLKVGGSVNREVRVGVTQAYVVFVTTLGGQWLERSFATFLSHVLDLVSHPRATQTHVEAVYSRRCVSFILRATVGSLLGEKAQIAAAKEICQAIGKQMKAVEAVVNDTSGENKSGAADIAASQHVMVCALQELGSLVQSLNATASPLIQEASIGLLETVTSVLLHPSMAARLAAAWCLRCVAVALPFQLTPFLDRC-AERLNSLKTSPEAVSGYSFAMAALLGGVHQCPLGIPHAKGKMVVSIAEDLLRTAAQNSRLSLQRTQAGWLLLGALMTLGP-SVVRYHLPKMLLLWRNVFPRSLKELEAEKARGDSFTWQVTLEGRAGALCAMRSFVAHCPELLTEDVIRKLMTPIECAMTMMSHIPSVIKAHGAHLKASAAMVRLRLYDILALLPPKTYEGSFNALLRELVAEFTLTDNSANTTTSLLRSLCHYDDSVLLGSWLQETDHKSIEDQLQPN-----------SASGSGALEHDPSSIY-------------------------------LRIPAGEAVPGPLPLGVSVIDASVALFGVVFPHVSFKHRLQMLDHFAECVKQAKGVRQQAVQLN-IFTAVLSALKGLAENKSTLGPEEVRKSALTLVMGALDN--PNPILRCAAGEALGRMAQVVGEATFIARMAQYSFDKLKSARDVVSRTGHSLALGCLHRYVGGIGSGQHLKTSVSILLALAQDGTSSEVQTWSLHSLALIVDSSGPMYRGYVEPTLSLVLTLLLTVPPSHTEVHQCLGRCLGAIITTVGPELQGNGATISTIRSSCLVGCAITQDHSDSLVQAAAISCLQQLHMFAPRHVNLSSLVPSLCVHLCSSHLLLRRAAVACLRQLAQREAAEVCEYAMSLAKSSGDKESSGTNVSPFAPGASSRSDIHCRHQGVNITETGLEGLLFGMLDRETDRKLCSDIHDTLGHMLSSLAVEKLSHWLMLCKDVLAASSDMSTATPLSSGK----------DEEFEKKDEMDDDTMFTTLGEEDKSKP--FVAPRWATRVFAADCLCRIINLCENADQAHFDLAMAR-SAKLRNPTNDLLVLHLSDLIRMAFMAATDHSNQLRMAGLQALEDIIKKFASVPEPEFPGHVILEQYQANVGAALRPAFSQDTPSDIIAKACQVCSTWIGSGVVS-DLNDLRRVHNLLVSSLDKVQAGKGSSSQLYRES---ATTMEKLAVLKAWAEVYVVAMNIKKEAESKPKRAVKNTD-----DDDDDDSTIDELPPDSLITLVQ--------------------PELPILSRLWLAALKDYALLTLPAEFASQLPPDGGAFYTPETIDTARLHYRNSWAPILHAVALWLNSTGFTCSESAEAAAISA-----------------------LQKRSIPVNLSQASGAIPSAKSLAEINKDRMHLILGVSIQFLCSPRPEEP-------------VEHVTACLQALHTLLDSPYAR-------IHIAEDQLIGVELLSVLHRLLLTWNPPSVQLLVTGVVQQIVRAAQDYLQEKRNTLNEDDI-EKESCPVLGEGGDSGG-----------------------------------LIPGKSLVFATLELLMFILVRHMPHLSTK---------------MSDSPSHIATKTRLSEESARLVAATVTILSDLPSLCSPAGCMTILPTILFLIARILKDTAIKSADNQVPPP----VSAALQGIKSIVTLSMAKTED-TQKQWTALIRSTLACILEYSQ--PEDSVPVPDEVSMLTAIALFLWSAGSEIIGVQSLQNGCIYRFKNALNSCDPWVQAKCYQLLLSVFQHSNRALSTPYIHSLAPIVVEKLKAVERNRPGSSTELLAVQEGIKVLETLVALGEEQNR---------------------VQLLALLVPTLIS--YLLDENSFASASTASKDLHEFALQNLMHIGPLYPHAFKTVMGAAPELKVRLETAVRASQAS-----------------------------KAKVATRQPAPTVHSAPTIKLKTSFF-----------------------------------------------", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "E1C8J1-1", "uniprot_id": "E1C8J1_CHICK", "id": "E1C8J1-1", "name": "HEAT repeat-containing protein 5B", "aln": "------------------------------------------------MELAHSLLLNEEALAQITEAKR--PVFIFEWLRFLDKVLVAANKTDVKEKQKKLVEQLTGLISSSPGPPTRKLLAKNLAALYSIGDTFTVFQTLDKCNDIIKSKDDTAAYLPTKLAAVACVGAFYEKMGRMLGSAFPETVNNLLKSLKSAESQGRSEILMSLQKVLNGLG-GAAASCHRDIYKNAR-SLLTDRSMAVRCAVAKCLLELQNEA-VFMWTAELENVATLCFKALENSNYGVRVAVSKLLGTVMATALIPKQATVMRQN--------------VKRATLEEVLELMATGFLRGGSGFLKSGGEMLKVGGSVNREVRVGVTQAYVVFVTTLGGQWLERNFATFLSHVLDLVSHPRATQTHVEAVYSRRCVSFILRATVGSLLGEKAQIAAAKDICQAIGKQMKAVEAVVNDANSENKAGAADVAASQHVMVCALQELGSLVQSLNATASPLIQEPSIGLLETVTSVLLHPSMAARLAAAWCLRCVAVALPFQLTPFLDRC-AERLNNLKTSPEAVSGYSFAMAALLGGVHQCPLGIPHAKGKMVVSIAEDLLRTAAQNSRLSLQRTQAGWLLLGALMTLGP-SVVRYHLPKMLLLWRNVFPRSLKELEAEKARGDSFTWQVTLEGRAGALCAMRSFVAHCPELLTEDVIRKLMTPIECAMTMMSHIPSVIKAHGAHLKASAAMVRLRLYDILALLPPKTYEGSFNALLRELVAEFTLTDNSANTTTSLLRSLCHYDDSVLLGSWLQETDHKSIEDQLQPN-----------SASGSGALEHDPSSIY-------------------------------LRIPAGEAVPGPLPLGVSVIDASVALFGVVFPHVSYKHRLQMLDHFAECVKQAKGVRQQAVQLN-IFTAVLSALKGLAENKSTLGPEEVRKSALTLVMGALDN--PNPILRCAAGEALGRMAQVVGEATFIARMAQYSFDKLKSARDVVSRTGHSLALGCLHRYVGGIGSGQHLKTSVSILLALAQDGTSPEVQTWSLHSLALIVDSSGPMYRGYVEPTLSLVLTLLLTVPPSHTEVHQCLGRCLGAIITTVGPELQGNGATISTIRSSCLVGCAITQDHSDSLVQAAAISCLQQLHMFAPRHVNLSSLVPSLCVHLCSSHLLLRRAAVACLRQLAQREAAEVCEYAMSLAKNAGDKENSGININTFPPGAGARRDGHSRHQGVNITETGLEGVLFGMLDRETDRKLCSDIHDTLGHMLSSLAVENLSHWLMLCKDVLAASSDMSTAAPLGGGK----------DEESEKKDEMDDDTMFTTLGEEDKTKP--SVAPRWATRVFAADCLCRVIMLCENANKAHFDLALAR-SARLKNPKNDFLVLHLSDLIRMAFMAATDHSNQLRMAGLQALEDIIKKFASVPEPEFPGHVILEQYQANVGAALRPAFSQDTPSDITAKACQVCSAWIGSGVVS-DLNDLRRVHNLLVSSLDKVQAGKGSSSQLYRES---ATTMEKLAVLKAWAEVYVVAMKIKKEAEAKPKRVLKSTE-----EDEDDFGTVDELPPDSLITLVQ--------------------PELPSLSRLWLAALKDYALLTLPAEFATQLPPDGGAFYTPETIDTARLHYRNSWAPILHAVALWLNSTGFSASESTEETAAAMPN---------------------SQKRATSIMLNQTPGTPPTTKSLPELNKDRMHLILGVSIQFLCSPRPEEP-------------VEHVTSCLQALHTLLDSPCAR-------IHIAEDQLLGVELLSVLHRLLLTWDPTSVQLLVTGVVQQIVRAAQDYLQEKRNTLNEDDIGEKENPLALGEGGESGG-----------------------------------LVPGKSLVFAAMELLMFILVRHMPHLSSK---------------VSDSPSHVAAKSHLSEESARLVAATVTILSDLPSLCSPAGCMTVLPTILFLITRVLKETAVKSADNQVPPP----VSAALQGIKTIVTLPTVKTDE-TQNQWASLIRSTLASVLEYSQ--PEASKPVLDEVSVLTAITLFLWSASTEIIGVQSLQNGCINRFKNALNSSDPWVQAKCYQLLLSVFQHTNRALSTPYIHSLAPIMVEKLKAVERNRPTNNLELLAVQEGIKVLETLVALGEEQNR---------------------VQLLALLVPTLIS--YLLNENAFASASTASKDLHEFALQNLMHIGPLYPHAFKTVMGAAPELKTRLETAVRASQAS-----------------------------KAKAAARQPPPTVHSTPTIKLKTSFF-----------------------------------------------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "A0A0R4ISV1-1", "uniprot_id": "A0A0R4ISV1_DANRE", "id": "A0A0R4ISV1-1", "name": "HEAT repeat-containing protein 5B", "aln": "------------------------------------------------MELAHSLLLNEEALSHITEAKR--AVFIFEWLRFLDKVLIAANKVDVKEKQKKLVEQLTGLISSSPGPPTRKLLAKNLAVLYSIGDTFTVFQTLDKCNDIIKSKDDTAAYLPSKLAAVACVGAFYERMGRMLGSSFPETINNLLKALKSAEAQGRGEILLSLQKVLSGLG-GAAASCHRDIYKNTR-SMLSDRSMAVRCAVARCLLELQNEA-VFIWTTELENVATLCFKALEGSTYDVRVAVSTLLGTVMATALMPKQATVMRQN--------------VKRATLEEVLELMATGFLRGGSGFLKSGGEMLKG-ASVSREVRVGVTQAYVVFVTVLGGQWLERNFAVFLSHLLELVAHPRATQTHVEAVYSRRCVSFALRATLGGLLGEKAQIAAAKEICLAISKQMRAVEAVVNEQSSENRTGAADVSASQHVMVCALKELGRLVQSLSATASPLIQEPSIGLLETVLSVLLHPSMAARLAAAWCLRCVCVALPHQLTPLLERC-ADCINTLKNSPEAVSGYSFAMAALLGGVHQCPLGVPHSKGKMVVSIAEDLLRSAAQNSRLSLQRTQAGWLLLGALMTLGP-SLVRYHLPKMLLLWRNVFPRSQKELEAEKARGDSFSWQVMLEGRAGALCAMRSFVAHCPELLTEDVIRRLMTPIECAMTMMSHIPAVIKVHGAHLKASAAMVRLRLYDILALLPPKTYEGSFNALLRELVAEFTLTDNSANTTTSLLRSLCHYDDSVLMGSWLQETDHKSIEDQLQPN-----------SASGSGALEHDPSSIY-------------------------------LRVPAVEAVPGPLPLGVSVIDASVALFGVVFPHVSFKHRLQMLDHFAECIKQAKGVRQQAVQLN-IFTAVLSALKGLAENKSSLGLEEVRKSALALVMGALDN--SNPILRCAAGEALGRMAQVVGEASFIARMAQHSFDKLKSARDVVSRTGHSLALGCLHRYVGGIGSGQHLKTSVSILLALAQDATCHEVQTWALHSLALIVDSSGPMYRGYVEPTLSLVLTLLLTVPPSHTEVHQCLGRCLGALITTVGPELQGNSVSISTIRSSCLVGCAIMQDHSDSLVQAAAISCLQQLHMFAPRHVNLSSLVPSLCVHLCSSHLLLRRAAVACLRQMAQREAAEVCEYAMSLARRAGDTKDNS-------------------TTNLNITETGLEGVLFGMLDRETDRKLCSDIHDTLGHMLSSLAVEKLSHWLKLCKDVLAATTEVGGAVASDSRRKD-------DDEDSEKKDEMDDDIMFTSLGQDEKMKA--TVAPRWVTRVFAAECLCRIIHLCENADHAHFHLAEAR-IAKIKNPEADFLVLHLCDLIRMAFMAATDHSNQLRMAGLQALEDIIKKFAAVPDPEFPSHVILEQYQANVGAALRPAFSPDTPSDITAKACQVCSAWIGSGVVS-DLNDLRRVHNLLVSSLDKVQTGKSSSSQLYSES---ATTMEKLAVLKAWAEVFVVAMDIKQESRARPVRPPAGED-----EDEDE--AADVLPPDSLMVLVQ--------------------PELPSLSRLWLELLRDYALLTLPAEFSSQLPADGGAFYTPETIDTARLHYRSSWASVLHAEALWLSSTGFG---ITEDSAASG-------------------------------------AAVQPAKHPEELVKDRLHLLLGISIEFLCFPRAEEP-------------IEDVMSCLRAVCTLLDSPIAR-------THIAEDQLLAVELLNVLHRLLLTRDPSSVQLQVTAVVQKTIHAAQEHLEQRRSNKGGVNE---DGVCVLGEGADSGE-----------------------------------LLPGKSLVFAAMELLVFILVRHLPQLKEK---------------NTDT--CRRSPQSLSEHSSRLVANSVTALAELPSLCSPAGSMTILPTVLFLITGVLRETAVKTADNSVSAP----VSAALQAIKTILSSTAAHTHA----QWSALVRSSLATVLEDSQ--PSD---SVDEVSFLAAITLFLLSASGDLMSVCVLQKGCIERFTHALNSADPWTQARCCQLLLSILQQPSRSLSVPFIHTLAPLLVEQLKSVERRRVCNAAELQAVQERVRVMETLVNMAEEHNR---------------------VQLLALLVPTLVS--YLLDDSSFSSSSSSSKGLHDFALQSLMHTGPLYPAAFMTVIGAAPELKTRLEAAIRSKQAHS----------------------------RAKSTARQTLPAAPAAPTIKLKTSFF-----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KGF6-1", "uniprot_id": "A0A0B4KGF6_DROME", "id": "A0A0B4KGF6-1", "name": "HEAT repeat-containing protein 5A", "aln": "MENLNFARTPQFLRKVISEARRSFINSDHFSASSTRGRSETEEEAISEMELAHTLILNEDALKQLPEHKR--PVFELEWLRYLEKALPLVSKAEIKASQKKLVQQLSERIQGAPGPPIRKLIASALATLFSVGDTFMLFDTVNACNDILKNKDDSPSYLPTKLAAICVLGSMYEKLGRMMGRTYEDTVQILIRTLRNAESQARIEIMHTLEKVSAGMG-TAIANVHKDIYKAAK-HCLLDRVMAVRVAAARCILKMIYSA-PFLYQTELESLGTLCFRAFDGSNYEVRCAVAQLLGTLLAYTQQLAEAATSKKKQGQAVAIQAGKGATQRLVSLDEALGILMSGFLRGGASFLKGTGEIIKGSSGVNREVRVGVTHAYVVFVQFMGSVWLERQLSTFLAHVLDLVANPKAACSHVDAVYSRKCISFILRSTIGKMLGEKAQSAACKELVHLVAKQMNSIDFNPENAKDSNQ----ETLFSQHLLVCALQELSSLLIGLGTTAQNLLGDQSLQAIDATCAVLVHPCAAARLAAAWCLRCACVAVPGQITPLIDRF-VEAIEQMRSSPEAMAGYSCALAAILGSVRYSPLGIPHTKGKVVFNCAEELLRSASQNSRMSLHRTQAGWLLIGAIMTLGS-PVVKGLLPRMLLLWRNSFPRSNKELESEKARGDAFTWQVTLEGRAGALSVMHSFLLNCPDLLNEDITRRLLTPIESALAMLVNLASVLKSYGTQLKAPAAMVRLRLFETLTLLPANALEASYTHLLRMLVSEFTLSDNAANTTNSLLRTLCHGDDSIILGTWLQETNHRTIEDQMEPNRKVDGEHLQPNSAAGSGALEHDPCCLYRPRSAQGNGSSSNGSSATSTGGSNGGGGSNIQQISKAQQCPGPLPLGVAVIDMAVTLYGTIFPKVANKHRLQMLEHFTECIRQAKSSRQEAVQMN-IFTALLCALKNLTDSKTSLGQEDVRKSATALIVASLTS--ANSTIRCAAGEALGRLAQVVGDSHFTAELAQNSFDKLKSARDVVTRTGHSHALGCLHRYVGGMGSSQHLSTSVSILLALGQDSASPVVQAWSLYALAQIADSGGPMFRGYVEATLTLCLKLLLTVPHAHVDVHQCVGRVVNALITTVGPELQGGGGAVATMRGSFLCSAALLQSHSDPLVQAEAIGCLQQLHLFASKSLQLEELVPTLVGMLACNYFILRKASVSCLRQLAHREAKEVCELALTINAEQLP--------------------------DLVITEYGLPGLLFSLLDTETDAEMLRNIHDTLTSMLQMLAADNLSSWLSLCKNVLTVAVEGGLNDDPAAGEQSKSKEAGGEDDEEDEEEEYADDVTEYRAEENTSTHP--AVQPRWPTRVFAAQCVRRIIASCEAASSVHFDLLQAK-EQQLIRSRGDYLILHLAELIRMSFMAATSDSDQLRLEGLRTLQEIIDRFANVPEPEFPGHLLLEQFQAQVGAALRPAFAPDTPSHVTAAACEVCSAWIGSGVAR-DIGDLKRVHQLLVSSLDKLSS-KTNSTQLYNES---MATLEKLSILKAWAEVYIVAMIGNGKAPASLLNLQSQQSGFQSLTNLETDSDVPDSRGESLLGLVQ--------------------PELHNLSTHWLSAMKDHALLLLPAEFQSQLPHDGGAFYTTDTINSSKPHYMTSWPPILYASALWLRDEGFARHLDTSEAAAES---------------------------------------NNNQITHGSLSADRFHMIFGICMEALCSMRSSER-------------PRNIVSCLRSLHSIFDSDWAR-------RQLVKDRALTIELCHVLHRQILTRDELLVQLLCVEILKQTIRAAREDLERKRDDNANS-----EDGKGGERHGEDDS-----------------------------------MQPGSSHVYAVLEVCLCLFVRQIPTMNPTRQGAGGSGLQLDF-AYAKMATGSSFFSVLGDENGLLVSSGLQCVEQLMDLCTPKGALAILPTVLYMTTSIVKEIANKSAIDSTILANTCAVKSALQCLRSVCVHKWAKVEE-TTEEWQQLLQSALATIVDLTKTAGDNEERKVDEVTMLLAITVFILHTPASVVATPSLQYPCINHFRQCLQSENLSVKLRCIETTRSIFARAELKTATPYIHALAPRIIESLYAESSKVPTSELELQVTLESIVTVEQLIDLSEPQNRN--------------MNLLQDIQMLTLLVPVLIG--FLAEPSRLRTLPKYQRQLHDQALQWLLKIGPKYPQEFKALMGQTPELRQKLEAAIRSQQQSIN-------------------------IAQKASEAQRNLLAKPQKPTIKLKTDFSNFQ--------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "F4HRS2-1", "uniprot_id": "SWTIE_ARATH", "id": "F4HRS2-1", "name": "Protein SWEETIE", "aln": "-------------------------------------MTKNIASDNVPLSRFGVLVAQLESIVASASQKNPDPLLCFEILSDLISAIDEEPKESLLVTQRKCEDALYSLVTLGARRPVRHLASVAMAKIISNGDSISIYSRASSLQGFLS--DGKRSDPQRVAGAAQCLGELYRHFGKKITSGLFETTSIVTKLVKFNEDFVRQEAFILLHNALEGCGGTAAATAYSEAYRLITRFSTLDKSFVVRIAAARCLKAFSNIGGPGLGTSEFDTLASYCVKGIEDSESSVRDAFAEALGSLLALGMHPEAHVQPRGK------------------------GPFPPAKKLEGGLQRHLILPFTKAVGSRAKNTRFGLALSWVFFLQAIRIRYLD-SDSELQDYSLPIMDMLRGDSS--IDAHALACVLYILRVGVIDQMME----PSQRSFSVFLGKQLQSSNASPS-----------MKIVALRALSYTLKTLGEVPHEFKEFFDDTVGAALSHFLDLVRVEAALTLRALAEVDPTCVGGLTSFAVTTLNALRESLSFEKGDKLKTDLASLHGQAATLAALVSISPGLSLGYPARLPRSVLEVSKKMLTESRRNVTVASSEKEAGWLLLSSLLNSMPKEEFGDQDFDILILWTDVFAGNPEHLIKQQA-----ELKSMLSVWSAAIDALTAFVRRFVSCNDGILLQPVLANLRSALSCVSTMAN--KRFSDVKTLVDILIIRILIAYQSIPDPLAYKSEHQQIIQLCTTPY--RDPSGFEESSCLKSLLDKRD-AWLGPWIPGRDWFEDELRYFQG--------------GEDGLAPS------------------------------------VWESKVSSFPLPETVKKTLVNQMVLCFGIMFASQDSQGMLSLLSVIQQCLKAGKKQQWRTASLTNICAGLLAGLKALHALRPQQLTTEVLSSGQAIFQNILTEGDICASQRRAACEGLG-LLARLGNDIFTARMTRVLLGDLSGVTDPNYGGSIALALGCIHHSAGGMALSSLVPATVNSVSSLTKT-SVLGLKIWALHGLLLTIEAAGLSFVSHVQAALGLALDILLTEESGWIDLSQGIGRLINAIVAVLGPELSPG----SILFSRCKSVIAEISSWQEIPTLLESVCFTQQLILFAPQAVSVHIHVKNLLMTLASRQPIIRRLSVSTLRHLVEKDP-------------------------------------------VSVIDEQIEDNLFQMLDEETDSEIGNLIRSTLIRLLYATCPSRPSRWMLICRNMALAASAGRSAETSIAENDP--------AYTRENLGDDDEDMVSSSSGKSIRANPDKDKTLRYRTRVFAAECLSLLPEAVGN-DAAHFDILLARNLASNRQSSGDWLVLQLQELISLAYQISTIQFENMRPIGVGLLSTILEKFKLVADPELPGHLLLEQYQAQLLSAVRTALDANSGPVLLEAGLQLATKIMTSGIIRSDQVAVKRIFSLLSRPLNDFNELYYPSFAEWVTSKIKIRLLAAHASLKCYIFTFLRKHHGEVPVEFEALLPMFSKS-----SDLLGRYWIQVLKGYSYICLCQNLKKSQCSFLDEILPHTVSRRLQPCLEEAWPVILQALVLDAIPVNHSVEEFSDRSLISTHRMVTLEAEDFQFLWGFAVLVLFQGMHPASSMQVIPFSSAKIKSSGDSSINESSFQGLKLYEIALPVFQSLSAGRFFSSGFLSIDLCQELLQVLSYSFHMDSSWDILAVSVVQQISQNCPKDFLESEEFAYSTIELCLGYLFKILHRHNEISPDDGIWDNMLSPLFISIKTLVKRFELKHRLNSAPLAFLLSGYKCIRQVPTDAYLPKALEIVKSTNDLLLELTRASSQKPYTDGTNFAADSGFHLRAIFGACLHMVGDLTRDCINGIQLVDSKRSGLRKLLQLKLVFCLEQLFSLAKLAYEFDCPVDETNTNSICIVMLKSCQISIAAVVKDSNVQVQATVLQVLKSLVQRYNNPEEKSFVILFVGELIGDIVSLMQRALLKPVNTESVVIAGECLRFIMLLQTHSITDELQKGFMSLFLEVVLVVFSKTSDGVSQEVLELRNVAVRLVSHLAQLPSSAVHFKDVLLSLPVTHRQQLQDIIRASVSKDSALAKPKSLVPAMDIKLPAPVVATPEKVTSTANMVKEEALSTMPTSFNQVSTVESGTDEEEEEEEDDDDDDWDTFQSFPASTNLEGSESKTESVAEEEPDLPGRSSIQDDESNAEETDDQHLASDHATDITREDSNDKSKEVVEEETVEPCFTTREDSVDKSKEVEEETVKPCLIEDALTSQNDKTSSGDHPVEINEQSVESKNLESENIGTDIKLASTEVESPALDDLEPQQIQKSPEDESSKEHVGADVIVTEETIAENKSDVDYI", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. *: : ::: .. *. .:: :* * * ..: * .: .*:* : * : .. * *:* : :* : * **: ::. . :.:: *.. : .* :* :*.::*: : :* . : : :: * * * : *.:. * * * *. : : *: *: :.** *.*:*: : . : :*::.:.: *.:.::.* ** *.: **:::* . : : : .. *. : : * .. ::.*.*:: ::*.*: : :*: . : : : * :: :. : .:: *: : ** : : * .: :.: :.**:.: : . : : : :*: *. : : . : :: . . * . . *: :..: : : : ::.. :: * : ::**::. .** * : *.. ::.:* : :* :: ..:*****:.:::. . . :*:** : *. . :.* ::* : *. :.*: .: :*: . . : ::: :..*:: : :. * .. . :: * :: . : :... ::: .: : * :. .* *::* . * :*.*: : * : . *...* . . . * * .: :::: * :* :*. : *.:*. : :*:: .* : .:..:. * :.:*..** * :. :* .*. ::. * . . * ** *.** : :*: * *.::: :..*... * . : ****:*: .**:. .. : ::*. : :* : : :: *:*:.* ::.* : .:*:.:* * * :*** . :: * :** :.*:::.:****. . : : . * .. .: . :: *** :**.: :.: * .* *.. ::*: :*: **::..::. : : : : . ** :** *** :: *:.** :* . .. * *: :*::: .: . . :: : :* :. :. *: ******:*: : . .**.: *: .. * *:*:* :** ::: :* . :::* *: *. *:.:* *.:**:*.*::***:**:: :*:*.*: :: . : . ::.: : **: * ::*:..** .*: .. . : * : : **.: .:: : . : * : * * *. * :: .* :*.:. : * . : * : .: * : . : . . : .: :*: . : :. : . : ** : .:: :: . : :: .. : : : .: * . . : . . : . * : ::: : : :.:: : . . * : * .* . . :: : :: : . * * : :: : : *. . : :.. :. . :*: . : : . *. : : . *:. . ..* : : . .: . : * .: : :: * * . : : . . .: : * : . . . . * : : ::. ::.: . : : . *** : ", "identical_positions": 263, "similar_positions": 651, "identity": "10.84%" }, { "cls_id": "homologset.oma.815543", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PRF0-1", "uniprot_id": "HTR5A_MOUSE", "id": "Q5PRF0-1", "name": "HEAT repeat-containing protein 5A", "aln": "MELAHSLLLNEEASNQLGAVQKAEFIFEWLRYLEKLLLATNREDVREKQKTLVGQLLSLLNSSPGPPTRKLLAQDLAILYSVGDTVSVYETIDKCNDLIRSKDDSPSYLPTKLAAVVCLGSLYKKLGRILANGFTDTVVNILKAMKSAESQGRYEIMLSLQSILTGLGAAAAPCHRDVYKAARSCLTDRSMAVRCAAAKCLLELQNEAIFMWSTDVDSVATLCFKSFEGSNYDVRISVSKLLGTVLAKAVTAKHPG-AGSKQSARRVSLEEVLELLGAGFLRGSSGFLRASGDMLKGNSSVSRDVRVGVTQAYVVFVSTLGGAWLEKNLAAFLSHILSLVSQSNPKATQTQIDAVCCRRCVSFILRATLGGLLGEKAQIAAAKEICQAVWRLKKVMDAALSDGNVETRLSSTDVAASQHVLVCALQELGNLIHNLGTTAAPLLQDSSTGLLDSVISVVLHPSISVRLAAAWCLHCIAVALPSYLTPLLDRCLERLAILKSSPEAVTGFSSAVAALLGSVTHCPLGIPHGKGKIIMTIAEDLLCSAAQNSRLSLQRTQAGWLLVAALMTLGPAVVSHHLTRVLLLWKCVFPASPRDLETEKSRGDSFTWQVTLEGRAGALCAVKSFISHCGDLLTEEVIQRLLPPLPCAVDLLTQLSSILKTYGSSLKTPSIVYRQRLYELLILLPPETYKGNLCVILKELAAELTAPDTQAAASTCLLPALCHPDDLLILSPLLQETDHRFIEEQLLLGNGVACGSLEYDPYSIYEKDVEGDSVPKPLPPALSVISSASKLFGVVCATVDEAQRVLILEQLLNSIKHTKGARQQTVQLHVVSAISNLLKYVAGSKQSLGP-EVRRLVLTLVLGALESPTPLLRCAASEAWARLAQVADDGAFTAGLAQLSFDKLKSARDVVTRTGHSLALGSLHRYLGGIG-PQHLSSCIGVLYTLSQDSTSPDVQTWALHSLSLTIDSAGALYHVHVESTLSLIVMLLLNVPPTHAQVHQSLGRCLNALITTLGPELQGSNTSVSALRTSCLLGCAVMQDHPGCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLC---------VNLCSPYLLLRRAVLACLRQLVQREAAEVSEHAIMLARD-GRD--AAADANLREVGLEGALLALLDRETDESLCQDIRETLHHMLTSMAVGKLTLWLKLCKDVLAASADFTAVTCVDTMQEEEGDRGDDASVLT-RGDDKPHPFSNPRWATRVFAADCVCRIINQCENANRAHFDIALAQEMKKRDSRNDFLVLHLADLIRMAFMAATDHSDQLRLSGLDTLLVVIRRFADIAEPEFPGHVILEQYQANVGAALRPAFTSETPPDITAKACQVCSAWIASGVVSDLSDLRRVHQLLVSSLTKIQAGKEALSQLYNESASTMEILAVLRAWAEVYIIAVQRHKN----HKQALKTTVNSEDSMRNGSSSAAGLLDLVCTDLATLSKLWLAALQDFALLTLPAEFASQLPTEGGAFYTAETSKSAKLHYHDSWALILHAAALWLTSTGF--ADPDEGGANLSRPVTPTSMCQGSSSSGAAVKSPEDVYTDRFHLILGISVEFLCSLRSDASLESIMACLRALQALLDVPWPRWRIGSDQDLGIELLNVLHRVILTRESPAIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGASEKETLPEFGEGKDTGGLVPGKSLVFATLELCVCILVRQLPELNPKLAGSPGGKASKPKTLLEEGSRLVAAALAILAELPAVCSPEGSISILPTVLYLTIGVLRETAVKLPGGQLSCTVTASLQTLKGILTSPMARAEKSHEAWTSLLQSALATVLDCWSPVDGA-QEPDEVSLLTAVTVFILSTSPEVTTVPCLQNRCIEKFKAALESKDSVVQMKTCQLLHSIFQYPKPAVSYPYIYSLASSIVEKLQDIARRKPEDATELQLCQEGIKLLEALVAIAEEEHRAQLVACLLPILISFLLDENALGSATSVTRSLHDFALHSLMQIGPRYSSVFKRVMASSPALKARLEAAVKGNQESVRVD-PPSKHAKNLARNS-SIQLKTNFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LG41-1", "uniprot_id": "A0ABK0LG41_RAT", "id": "A0ABK0LG41-1", "name": "HEAT repeat-containing protein 5B", "aln": "MELAHSLLLNEEASNQLGDVQKAEFVFEWLRYLEKLLLATNRDDVREKQKALVEQLLSLLSSSPGPPTRKLLAQNLAILYSIGDTFSVYETIDKCNDLIRSKDDSPSYLPTKLAAVVCLGSLYKKLGRILANGFTDTVGNILKAVKSAESQGRYEIMLSLQSILTGLGAAAAPCHRDVYKAARSCLTDRSMAVRCAAAKCLLELQNEAIFMWSTDLDSVATLCFKSFEGSNYDVRISVSKLLGTVLAKAVIAKHPGGAASRQSTRRVSLEEVLELLGAGFLRGSSGFLRASGDMLKGSSSVSRDVRVGVTQAYVVFVSTLGGAWLEKNLAVFLSHILSLVSQSNPKATQTQIDAVCCRRCVSFILRATIGGLLGEKAQIAAAKDICQAIWKLKKVMDAVLSDGNLETRLSSTDVAASQHMLVCALQELGNLIHSLGTTAAPLLQDSSTGLLDSVISVVLHPSISVRLAAAWCLHCIAVALPSYLTPLLDRCLERLTTLKSSPEAVTGFSFAVAALLGAVTHCPLGIPHGKGKIIMTLAEDLLCSAAQNSRLSLQRTQAGWLLISALMTLGPAVVSHHLPRVLLLWKCVFPVSPKDLETERSRGDSFTWQVTLEGRAGALCAVKSFISHCGDLLTEEVIQRLLPPLPCAVDLLTQLSSILKTYGSSLKTPSVVYRQRLYELLILLPPETYKGNLCAILKEVAAELTAPDSQVAASACLLPALCHPDDLLILSPLLQETDHRFIEEQLLFGNGIACGSLEYDPYSIYEKDVEGDSVPKPLPPALSVISSASKLFGVVCANVDEAQRVLILDQLLNSIKHTKGARQQTVQLHVVSAISNLLKYVAGSKQSLGP-EVRRLVLTLVLGALESPNPLLRCAAAEAWARLAQVVDDGAFTAGLAQVSFDKLKSARDVVTRTGHSLALGSLHRYLGGIG-PQHLSSCIGVLYTLSQDSTSPDVQTWALHSLSLTIDSAGALYHVHVESTLSLIVMLLLNVPPTHAQVHQSLGRCLNALITTLGPELQGNNTSVSALRTSCLLGCAVMQDHPGCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLCEILLDNSVLVNLCSPYLLLRRAVLACLRQLVQREAAEVSEHAVMLARD-NRDNNPAADTNLREVGLEGALLALLDRETDGSLCQDIRETLHHMLTSMAVEKLSLWLKLCKDVLAASADFTAVTCVDTMQEEEGDRGDDASVLT-RGDDKPHPFSNPRWGTRVFAADCVCRIISQCENANSAHFDIALAQEMKKSDSRNDFLVLHLADLIRMAFMAATDHSDQLRLSGLDTLLVVIRRFADIAEPEFPGHVILEQYQANVGAALRPAFTSETPPDITAKACQVCSAWIASGVVSDLGDLRRVHQLLVSSLMKIQAGKEALSQLYNESASTMEVLAVLKAWAEVYIIAVQRHKN----HKQTLKTTINSEDSVRSGSASAAGLLDLVCTDLATLSRLWLAALQDFALLTLPAEFASQLPVEGGAFYTAETSKSATPHYHNSWALILHAAALWLTSTGF--ADPDEGGANLSRPVTPTSMCQGSSSSGPAVKSPEDVYTDRFHLILGISVEFLCSLRSDATLESITSCLQALQALLDAPWPRSRVGSDQDLGIELLNVLHRVILTRESPAIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGASEKETVPEFGEGKDTGGLVPGKSLVFATLELCVCILVRQLPELNPKLTSGPRDKASKPKTLSEEGSRLVAAALVILAELPAVCSPEGSVSVLPTILYLAIGVLRETAVKLPGGQLSSTVTASLHALKGILTSPMARAEKSHEAWTSLLQSALATVLDCWSPVDGAHQELDEISLLTAITVFILSTSPEVTAVPCLQNRCIEKFKAALESKDSVVQMKTCQLLHSIFQYPKPAISYPYIYSLASSIVEKLQEMDRRRPGDAAELQLCQEGIKLLEALVTVADEEHRAQLVACLLPILISFLLDENALGSATSVTRSLHDFALQTLMQIGPRYSSVFKNVMASSPALKARLEAAVKGNQESVRVD-PSSKQAKNLGRNS-SIQLKTSFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86XA9-1", "uniprot_id": "HTR5A_HUMAN", "id": "Q86XA9-1", "name": "HEAT repeat-containing protein 5A", "aln": "MELAHSLLLNEEAYNQLGEVQKAEFIFEWLRYLEKLLLATSRNDVREKQKTLVEQLLSLLNSSPGPPTRKLLAKNLAILYSIGDTFSVHEAIDKCNDLIRSKDDSPSYLPTKLAAVVCLGSLYKKLGRILGNTFTDTVGNILKAMKSAESQGRYEIMLSLQNILNGLGAAAAPCHRDVYKAARSCLTDRSMAVRCAAAK------NEAIFMWSTDLDSVATLCFKSFEGSNYDVRISVSKLLGIILAKAVISKHPGTAASRQSIRRVSLEEVLELLGTGFLRGSSGFLRASGDMLKGTSSVSRDVRVGVTQAYVVFVSTLGGAWLEKNFAAFFSHILSLASPSHPKATQTQIDAVCCRRCVSFILRTTIGGLLGEKAQLAAVKDICQAIWKLKKVMDAVMSDGNLETRLGSTDVAASQHMLVCALQELGNLIHNLGTTAAPLLQDSSTGLLDSILSVILHPSISVRLAAAWCLHCIAVALPSYLTPLLDRCLERLTGHKSSPEAVTGFSFAVAALLGAVKHCPLGIPHGKGKIIMTLAEDLLCSAAQNSRLSAQRTQAGWLLISALMTLGPAVVSHHLARVLLLWKCVFPASPKDLETEKSRGDSFTWQVTLEGRAGALCAIKSFVSHCGDLLTEEVTQRLLPPLPCAVDLLTQLSSILKMYGSPLKTPSVVYRQRLYELLILLPPETYEGNLCAILRELAADLTAPDIQVAASTFLLPPLCHQDDLLILSPFLQETDHRFIEEQLLLGNGVACGSLEYDPYSIYEKDVEGDSVPKPLPPALSVISSASKLFGVVCAHVGETQRLLILEQLLDSIKHTKGARQQVVQLHVVSSVSSFLKYVAGSKGCLGPEEMKRFALTLVMGALESPNPLLRCAAAESWARLAQVVDDGAFTAGLAQVSFDKLKSARDVVTRTGHSLALGSLHRYLGGISSSQHLNSCIGILYTLAQDSTSPDVQTWALHSLSLIIDSAGPLYYVHVEPTLSLIIMLLLNVPPTHAEVHQSLGRCLNALITTLGPELQGNSTSISTLRTSCLLGCAVMQDNPDCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLC---------VNLCSPYLLLRRAVLACLRQLVQREAAEVSEHAVMLAKD-SREE-LTPDANIREVGLEGALLILLDKETDERLCHDIKETLNYMLTSMAVEKLSLWLKLCKDVLAASADFTAVTCVDTMQEEEGDKGDDASVLTTRRDEKSHPFTNPRWATRVFAAECVCRIINQCENANSAHFDIALAQEMKKRDSRNDFLVLHLADLIRMAFMAATDHSDQLRLSGLEMLLVVIRRFATVPEPEFPGHVILEQYQANVGAALRPAFTSETPPDVTAKACQVCSAWIASGVVSDLNDLRRVHQLLVSSLTKIQAGKEALSHLYNESASTMEILAVLKAWAEVYIIAVQRHKN----HRQPLKTTTCLEDGIRNGSCSSDGLLDLVYADLGTLSRLWLAALQDFALLTLPSEFASQLPAEGGAFYTAETSENAKLHYYNSWALILHATALWLTSTGFVVADPDEGASNLSRPVTPTSMCQGSSS-GATIKSPEDVYTDRFHLILGISVEFLCSLRSDATMESITACLHALQALLDVPWPRSKIGSDQDLGIELLNVLHRVILTRESPSIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGAAEKETLPEFGEGKDTGGLVPGKSLVFATLELCVCILVRQLPELNPKLTGSPGVKATKPQILLEDGSRLVSAALVILSELPAVCSPEGSISILPTILYLTIGVLRETAVKLPGGQLSSTVAASLQALKGILSSPMARAEKSRTAWTDLLRSALTTILDCWDPVDETHQELDEVSLLTAITVFILSTSPEVTTIPCLQKRCIDKFKATLEIKDPVVQIKTYQLLHSIFQYPNPAVSYPYIYSLASCIMEKLQEIDKRKPENTAELEIFQEGIKVLETLVTVAEEHHRAQLVACLLPILISFLLDENSLGSATSIMRNLHDFALQNLMQIGPQYSSVFKSLVASSPALKARLEAAIKGNQESVKVKIPTSKYTKSPGKNS-SIQLKTSFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0XMK3-1", "uniprot_id": "A0A8V0XMK3_CHICK", "id": "A0A8V0XMK3-1", "name": "HEAT repeat-containing protein 5A", "aln": "MELAHSLLLNEEEYNQLGEYQKAEFIFEWLQFLEKLLPVTSRTDIKENQKKLVEQLTSLLNNSPGPPTRRLVAKNLAVLYSTGDTFSVFQTIEKCNELIRSKDDSPSYLPTKLAAVVCLGYLYKKLGRILGNSFTDTVGNVLKAMKNAESQGRYEIMLSLQNMLKGLGAAAVPCHRDIYKAARSCLTDRSMAVRCAAAKCLLELQNEAVFMWSTDLDSVVTLCFKSFEGSNYDVHLAVSKLLGTVLARALTSKQTT-VPTKHNSRRISLEEVMELLGTGFLRGSHGFLRASGDMLKGTSSVSRDVRVGVTQAYVVFASMLGGQWLERNFSAFLSHVLDLVSQSHPKAIQNQMDAIGCRCCVSFILRATVGGLLGEKAQIAAAKEICQAIWKLKKVVDASVSDSNLETRISTTDVTASQHVLVCALQELGSLIHGLGTTAAPLLQDSSSGVLDTVISVILHPSVPVRLMAAWCLRCIAIALPSYVSLLLNRCIERLNALKSSPEAVTGFSFAIAALLGAVKHCPLGIPHGKGKVIMTVAEDLLCSASQNSRLSVQRTQAGWLLIAALMTLGPAVVQYHLPRILLLWKCVFPSSPKDLETEKTRGDSFTWQVTLEGRAGALCAIRSFVSHCAGLLTDEVLQRLLPPLPSAVDLLTQLSSISKSYGNSLKTSSTVYRHKLYELLAVLPPKMCEGSFHAVLKELVVDLTIPDSQFDASTFLLPPLCHEDDLLLLGPLLQETDHRFIEEQLLLGNNIAGGSLEYDPYSIYEKLTKRDSVPKPLPPTLSVISAATALFGVIFCHIAETQRLQVLEQLLNSIKQTKGSRQQIVQLNVVSAFSTSLKHLANCKGSLGPEEVRRSALTLVLGALESNNPLLRCAAAECWARLAQVVSDSAFTAGLAQVSFDKLKSARDVVSRTGHSLALGCLYRYLGGIGSTQHLNACVGILYTLSQDSTSPDVQAWALHSLSLIVDLAGPLYHVHVEPTLSLVLMLLLTVPPTYTEVHQSLGRCLNALITTLGPELQGSSATVSALRTSCLLGCAVMQDNPDCLVQAQAIACLQQLHMFAPRHVNLSSLVSCLCEILLDNSVLVNLCSSYLLLRRAAVACLRQLVQREAAEVSEYAVALVKE-SRED-FTPDINIREIGLEGALLGLLDKELDQRLCRDIKETLSHMLTSMAVEKLSFWLKLCKDVLSASADFNTVASIDTTQEEETAKVDDASILTSESDERFHPFSNPRWSTRVFAAECVCKIINQCENAGSAHFDITLAQERKQRDSRDDFLVLHLADLIRMAFMAATDHSDQLRLSGLQTLQIVVRKFAAVPEPEFPGHLILEQYQANVGAALRPAFAPETPPDVTAKACQVCSAWIASGVVSDLNDLRRVHQLLVSSLVKVQAGKEAQSQQYNESTSTMEILAVLKAWAEVYIVAIEKQKNQSDSHNHSLKTANSAEESYRDVTSSASSLLDLVQADLGTLSKLWLAALQDFALLILPSEYASQLPAEGGAFYTAETIENARPHYYNSWALILYATSLWLTSTGFIVADPDEGVTNLSRPVTPTTMCQ-DSSTRPSVKSPEDVNTDRFHLILGISVEFLCSPRSDAAMENFIACLHALQALFDVPWPRSKIGGDQELAVELLNVLHRLILTRESPDIQLAALEVVRLILFAAQEHVKEKRRSAEVDDGAAEKETLPEFGEGKDTGGLVPGKSLVFATLELCVCILVRQLPQLNPKLTCSPAVQSGKHLLLSEDGSRLVSAALLILSDVPAICSPEGSVSVLPTILYLIIGVLKETAVKEQDGQLPLPVAASLQALKGLLSSPMARAEKSRTAWTDLLRSALVTVLDCWDQADGLLRELDEVSLLTAITVFIMSTSPEVTTIECLQKRCIEKFKVTLESKDPVVQYKCYQLLHSIFQHPNKAVSYPYIHYLASSIVGKLQETEKSKPENAAEFQVVQEGIKVVTALTAAAEEEHRAHLVTCLLPILISFLLDENALGSATNTAKNLHEFALQNLMQIGPQYSSVFKKLMASSPTMKARLESAVKGNQESIKVK--TAKLAKNPGKCS-SIQLKTNFL", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "A0A8M3AJX9-1", "uniprot_id": "A0A8M3AJX9_DANRE", "id": "A0A8M3AJX9-1", "name": "HEAT repeat-containing protein 5A", "aln": "MEQAHSLLLNEEACSQLPEHQRAEFVFEWLRFLKKLLPATDRADVKQKQKRLVEQLTTVLTSSPGPPTRLLLAQCLALVYRVGDSLTSSLTVDRCNDIIRSKDDSPSFLPTRLAAVACLGALYEQLGRLLINSFKETTTNLLKAMRSAESQGRCEIMLCVERILRGLGVSAVSCHRDIYKAARTGLTDRSMAVRCAAAKCLLELQREAVFLWSTELENVATLCFRALEGSNYDVRVSISKLLGTLLASALEPRQAI--APRPGSKRSSLEEVMELLSSGFLRGGAGFLRASGDMLKGTSSVSRDVRVGITQTCVVFVSILGGVWLETHFSRLLSLLMEWAS--HTRATQYPADAVSCRCCVSFILRATLGTLLGEKAQIAAAKEICQVISKQKRVVDASLHEGNMETRVSPADVAASQHVLVCALLELGSLVQDLSSTAAPLLQDTGIGMLDTVISVLLHPSASARLASAWCLRCIAVGMPAQVAVLLDRCVERLNALKSCPEAVAGYSAAIAALLGAVQLSPLGISHSKGKMVMTLAEDLLRSAAQNSRISIQRTQGGWLLLSALSTLGSTVMEHHLPRLLLLWKCAFPLSVKDVEMELRRGDSFTWQVTLEGRAGALCAIKSLVVHCKELLTDDVICCFVPLLSCAVALLTQLPSIIKSYGNQIKNAATVFKLRVYEILKLLQPKIYEESFGTVLKQLLNDLTGPEITACAERNLLPSLCYSQDLALLGPGLQDMDQRYIEEQLHGG-GSGGGTLEYDSFTIFEKSQE---VPTPLPPASALTVAAVQLFGVIFPHLSVQQRAQVLEQFCEFVRQLKGARQQTVQIHVTAAFFCTLKSLASSRRELGPEEVQRPALSLLLGALEGSNPLLRCMAAEGLARLVQVLNDPGFTVSLTLMSFDKLKTARDAITRTGHALALGTVYRYLGGISSPQYLSACVGVLFTLSQDNTSPEVQMWALHALSIVVDLAGPLYHSHLEASFTLVLRLLLSTPHTHVEVQQSLGRCLNALITSVGPDLQGEGAGVCAVRTSCLVGCAVMQDSQDCLVQAQAISCLQQLHMFAPRFVNLSSLVPSLCEILLDYSVLINLCSSYLSLRRAVVACLRQLAQREAVEVSEHAVALVKELPRRDNTQLDVTIKEVGLEGALFSLLDRESDPRLCRDIQETLVHMMSSAAESKLAHWLKLCKDVLSASADSAAAASVETQQEEDGDRYDDSSAFHAKSES-SGPFNNLRWSTRVFSMECVCRIIAQCENRDSAHFNMALAQEQRLHES-TDFLVLHLADLIRMAFMASTDHSDQLRLAGLQTLLVIIRKFSNVPEPEFPGHVILEQYQANVGAALRPAFHVDAPPNVTAKACQVCSAWIASGVISDLRDLRSVHQLLASSLAKVQVGRDVPSQLYNESTFTMESLAVLKAWAEVYITAVQGSRQ----RDSPVSHQQQQSEEAGTAGQAGAGLLKLVQTDLATLSRLWLAALQDHALLTLPPHYSSHLPSTGGSFYTAETVEQARPHYYSAWATILHATALWLNSTGF--IVVDEGPANLSRPVTPTSMGQ--STSLSNVKSPEDINSDRLHLILGISVEFLCSPHSGDQMENIHSCLQALQALLEVPWPRSKVGNDQALSVELLSILHRLIVTRESPSIQLAVLELVQQIICAAQEHVREKRHSAEVDDGAAEKETVPEFGEGRDTGGLVPGRSLVFGALELCLSTLVRKLPQLSPKLTGSPTGRGGQTCSLSATDCRLVTSALAILSELPSICSPEGSVSVLPTVLYLLLGVLKEAVKGSVGTESGQLVSGILQALRTLLTSPMSRAEKSRGAWTQLLQCALHTLLESWS-TDKVEPGVDEVTMLTSLTIFLLYASAEVTSVEPLQTRCIQTFRASLDSKDPVVLSRSYQLLLSLFQGP-APVARPFILALGGRLVSQLEEAEKSRPQGPAELQAVQDAIRALEALVFAADETHRPQLVAVLLPILISLLLDENALASAPAASRLLHESALRDLMRIGPQHSAVLKALMASAPHMKARLEAAVKGNQESVNSK---AQAPPAISKNTPSIQLKINFL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ********* .** *:***:****::*:*** .*.* *::::** ** ** ::*..******* *:*: **::* **:.: ::::**::*********:***:****.*** **::***:* * *.:*. *:***::.****** ****.:: :* ***.:*..****:*****: ************** .**:*:***:::.*.****:::*******::::***** :** *: .::. .: . :* *****:***.:*****. ************.**********:**: ***.* *** *** ::: ::* ::. .* :.:* * **: ** *******:*:* *******:**.*:***.: : *:*:** : :.*:***:..:**:****:***** ***.*::.*.:********:. *:**:::**:**** ..** :****:***:.:*: :: **:**:*** **.****:*:* *:*****:* .****.*.***::**:***** **:****:* ****.****::** ***.:*:.:**.*:******.** * :*:* * ********************::*:: ** ***::* ::* *..** *****.** * **. :*..: *:: ::**:* :* *: : .: .:*::: :** *: *. ***.**: :** :*.* **: *:*:***** * . . *:****.::*:** : **.****: :: :* ****: : ** :*:*: : ::: **:*** **::*.::. ** :*..: *** *::* .*:*::****. .***** *:* ***.** .* .**..*: :******:***.::****:**** ::******. .*:*.:*:*:*:**:**.***:** ****:**: :* **.**: *:*.:::*:: ***..* *:.:*:************::**:***..: :.::*****:******* .********:***********.*******..** :****.** ****.:******.****.****:*: *.:: * * .::*:******: ***:* * **:**:*** :*::* * **: *********:**** :.:.::* ***: : **:* : . :. **.* **.****: :***:** **** . ***:::**** : :* *****************:*********:**: * :::*:*: :.*******:***************** ::**::****************:*** *** *****.*** *:*.*::. *: ****: *** ****:******* *:: :: : .:. .: :. .**.** :**.***:********.*** **..::*:** **:****** :.* **:.:** **:*::***.**** *** :*********:* * *: . :*****: :**:************* :*. :*.: :**:*****::.**** ::*.** *.:***.:***:*:***** **** **:*: *: ******:***:********:****:******:********:****.:****:. ***:**:*.***: .* :. : * ..***::** **:::*::******:*:***:*** :***:*:. . : *:. *::*: :*:***:*****: ***.**:.** *:*:.*. .* **:::**::*:*:: :*.***:: **.***:.*:.:*: **.** : *** *:** * .:: *:* *.. :: :*:: : :* ..:*:: *:.*: : :*. *:* **.:**: *******:*****:*.**. : **: **: **:***::*:*:* ::**:* :*****:*:******:. . :: . .: : ***** .**", "identical_positions": 1118, "similar_positions": 579, "identity": "54.19%" }, { "cls_id": "homologset.oma.815557", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O54921-1", "uniprot_id": "EXOC2_RAT", "id": "O54921-1", "name": "Exocyst complex component 2", "aln": "--------------------------------------------MSRSRQPPLVTGISPNEGIPW---TKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCR-VGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIG------ILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPA-----NPLGIEIE-KCKLPQKNLEVLFHGMSADFT----------SENFSAAWYLIENHSNTSFEQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTR-NALNVLQRFKFLFNLPLNIKRNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVEAGIEDLRELLLKKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHKWTLKLMQDCKEGHMK---SLKGNPGPHSPMLDLDNDARPS--VLGHLSQTASLKRGSSFQSGRDDTWRYKTPHRVA--FVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGQIERSK-NVRQRQNDFKKMIQEVMHSLVKLIRGALLPFSLREGDGRQYGGWEVQAELSGQ---------WLAHVIQTIRLTYESLTALE-IPNDMLQIIQDLILDLRIHCIMVTLQHTAEEIKRLAEKEDWIV--------DNEGLTSLPCQFEQSIVHSLQSLKGVVDCKPGEASVFQQPK--TQEEVCQLCISIMQVFIYCLEQLSTKPDADIDTTHLSVDVS------SPDLFGSIHEDFGLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVS-----MASLKELDQRLFENYIELKADPIVGSLETGIYAGYFDWKDCLPPAGVRNYLKEALVNIIAVHAEVFTISKELVPRVLARVIEAVSEELSRLMQ-----CVSSFSRNGALQARLEICALRDTVAIYLTPESRSSFKQALEALPQLASG-------------------------------ADK------KLLEELLNKFKSSMHLQLTCFQAASPTVMKT----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D4H1-1", "uniprot_id": "EXOC2_MOUSE", "id": "Q9D4H1-1", "name": "Exocyst complex component 2", "aln": "--------------------------------------------MSRSRQPPLVTGISPNEGIPW---TKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCR-VGQAKNDKGDIIVTTKSGGKGTSTVSFKLLKPEKIG------ILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPA-----NPLGIEIE-KCKLPQKNLEVLFHGMSADFT----------SENFSAAWYLIENHSTTSFEQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTR-NALNVLQRFKFLFNLPLNIKRNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVEAGIEDLRELLLKKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHKWTLKLMQDCKEGHMK---SLKGHPGPHSPMLDLDNDVRPS--VLGHLSQTASLKRGSSFQSGRDDTWRYKTPHRVA--FVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGQSERSK-NVRQRQNDFKKMIQEVMHSLVKLIRGALLPLSLREGDGRQYGGWEVQAELSGQ---------WLAHVIQTIRLTYESLTALE-IPNDMLQIIQDLILDLRIRCIMVTLQHTAEEIKRLAEKEDWVV--------DNEGLTSLPCQFEQSIVHSLQSLKGVVDCKPGEASVFQQPK--TQEEVCQLCINIMQVFIYCLEQLSTKPDADIDTTHLSVDVS------SPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVS-----MASLKELDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPAGVRNYLKEALVNIIAVHAEVFTISKELVPRVLARVVEAVSEELSRLMQ-----CVSSFSRNGALQARLEICALRDTVAIYLTSESRSSFKQALEALPQLASG-------------------------------ADK------KSLEELLNKFKSSMHLQLTCFQAASPAVMKT----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96KP1-1", "uniprot_id": "EXOC2_HUMAN", "id": "Q96KP1-1", "name": "Exocyst complex component 2", "aln": "--------------------------------------------MSRSRQPPLVTGISPNEGIPW---TKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCR-VGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIG------ILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPA-----NPLGIEIE-KSKFSQKDLEMLFHGMSADFT----------SENFSAAWYLIENHSNTSFEQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTR-NALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDLHASGDPAWQCIGAQHKWILQLMHSCKEGYVK---DLKGNPGLHSPMLDLDNDTRPS--VLGHLSQTASLKRGSSFQSGRDDTWRYKTPHRVA--FVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGQIERSK-NVRQRQNDFKKMIQEVMHSLVKLTRGALLPLSIRDGEAKQYGGWEVKCELSGQ---------WLAHAIQTVRLTHESLTALE-IPNDLLQTIQDLILDLRVRCVMATLQHTAEEIKRLAEKEDWIV--------DNEGLTSLPCQFEQCIVCSLQSLKGVLECKPGEASVFQQPK--TQEEVCQLSINIMQVFIYCLEQLSTKPDADIDTTHLSVDVS------SPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVS-----MASLKELDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPTGVRNYLKEALVNIIAVHAEVFTISKELVPRVLSKVIEAVSEELSRLMQ-----CVSSFSKNGALQARLEICALRDTVAVYLTPESKSSFKQALEALPQLSSG-------------------------------ADK------KLLEELLNKFKSSMHLQLTCFQAASSTMMKT----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1P2A7-1", "uniprot_id": "F1P2A7_CHICK", "id": "F1P2A7-1", "name": "Exocyst complex component 2", "aln": "--------------------------------------------MSRARQPPLVTGISPNEGISW---TKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCR-VGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIG------ILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPA-----NPLGIEID-KGRFPQKDLETLFPGMSADFT----------SENFSAAWYLIENHSTASFDQLKMAVVNLKKQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTR-NALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHQWILQLMHNCKESYVK---EQKGTSLLHSSMLDLDSDVRPS--PIGHLSQTASLKRGSSFQSGRNDAWRYKAPQQVV--FVEKLTKLVVSQLPNFWKLWISYVNGSLFSETAEKSGQMEKSKKNARQRQNDFKKMIQEVMHSLEKLIRGALLPFSLKEGESRQYGGWEMKSELSGQ---------WLTHVIQTVRLSSESLTALE-IPNDMLQIIQDLILDLRVRCIIVTLQHTAEDIKRLAEKEDWVV--------DNEGLTSLPSHFEQCIVHSLQSLKTVLDCKPGEASVFQQQK--IQEDVCQLSIGILQVFIDCLEQLSTKPDGDIDTSHLSVDVS------SPDLFGSIHEDSSLTSEQRVLIALSNCRYLERHTFLNIAEHFEKHGFQGVDKITQVS-----MESLKELDQRLFEMYIESKADPIVGSLEPGIYAGYFDWKDCLVPAGVRNYLKEALVNIIAVHAEVFTISKDLVPRVMSRIVEAVSEELSRLMQ-----CVSSFSKNGALQARLEICALRDTVAIYLTPESNSSFKQALEALPQLSSG-------------------------------ADK------KLLEELLNKFKSSMHLQLTCFQTSSSAMIKT----------------------------------------------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "F1RXP8-1", "uniprot_id": "F1RXP8_PIG", "id": "F1RXP8-1", "name": "Exocyst complex component 2", "aln": "--------------------------------------------MSRSRPPPLVTGISPNEGIPW---TKVTIRGENLGTGTPDLIGLTICGHNCLLTAEWMSASKIVCR-VGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIG------VLDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPA-----NPLGIEIE-KGQFPQKDLEVLFPGMSADFT----------SENLSAAWYLIENHSNTSFEQLKMAVAHLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTR-NALTVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDLRAPGDPAWQCIGAQHRWILQLMHDCREGCAR---DLTGTSGLHSAVSDPDSDARPP--ALGHLGHTASLKRGSGFQSGRGDAWRYKTPQRVA--FVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGHIERSK-NVRQRQSDFKKMIQEVMHCLVKLIRGALLPPSAAEGGVRPGTGREVKAELSGQ---------WLAHVIQTLRLTYESLTALE-IPSDLLQTIQDLVLDLRGRCVAATLQHTAEEIKRLAEKEDWVV--------DSEGLTSLPCQFERRVVQSLQSLRGVLECRPGEASVFQQPK--TQEEVCQLSINIMQIFICCLEQLSTKPDADVDTAHLSVDVA------SPDLFGSIHQELSLTPEQRLLIVLSNCCYLERHTFRNIAEHFEKHNFQGIEKITQVS-----MASLKDLDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPTGVRNYLKEALVSIIAVHAEVFAVCKGLVPRVLSRVVEAVSEELSRLMQ-----CVSSFSRNGALQARLEICALRDILAAHLTPESRSSFKQALEALPQLSSG-------------------------------AERTSSHQCSLKAEKRRTRGTGNRPAVAWGGGRAKAAGRTAEPGQRQHAPAAGLLPGCPTACCEDLGVPPCCACPRPQCSRRQASV", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "E1BDW9-1", "uniprot_id": "E1BDW9_BOVIN", "id": "E1BDW9-1", "name": "Exocyst complex component 2", "aln": "--------------------------------------------MSRSRQPPLVTGISPNEGIPW---TKVTIRGENLGTGPADLIGLTICGHNCLLTAEWMSASKIVCR-VGQAKNDKGDIIVTTKSGGKGTSTVSFKLLKPEKIG------ILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPA-----NPLGIEIE-KGKFPQKDLEMLFPGMSADFT----------SENFSAAWYLIENHSNTSFEQLKMAITHLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTR-NALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLEKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHRWILQLMHGCREGCVR---DLKGPPGLHSTSLDLDAEVRAS--APSHLGQTASLKRGSSFQPGRDDAWRCKTPHRVA--FVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGHIERSK-NVRQRQNDFKKMIQEVMQCLVKLVRGALLPLGAAEGSGRQLGGWEGKAELSGP---------WLAHVIQTLRLTYESLAALE-IPNDLLQTIQDLVLDLRVRCVLVTLQHTAEDIKRLAEKEDWVV--------DSEGLTSLPCRFERCVVLSLQSLRGVLECKPGEASVFQHPK--TQEEVCQLSINIMQVFIYCLEQLSTKPDADVDTAHLSVDVS------SPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVS-----MASLKDLDQRLFESYIELKADPIVGSLEPGIYAGYFDWRDCLPPTGVRNYLKEALVNIIAVHAEVFTVSKDLVPRVLSRVVEAVSEELSRLMQ-----CVSSFSRNGALQARLEICTLRDTVAAHLTLESRSSFKQALEALPQLSSG-------------------------------ADR------KLLEELLSRVKSGMHLQLACFQAAPPPAVKT----------------------------------------------", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q9VQQ9-1", "uniprot_id": "EXOC2_DROME", "id": "Q9VQQ9-1", "name": "Exocyst complex component 2", "aln": "-----------------------------------------------MAPQPVVTGLSPKEGPPG---TRVIIRGEFLGTRVQDLIGLKICGSDCLLSAEWKSPNKIIAR-TGPAKG-KGDIIVTTLSGGVGTSTVQFRAYH-ETIG------PLKESAVWIEESPSQNFAWGR-RTLAQSGLTQE-----DPLGLSIEGNEQKIPEDLRDLFPEACGDLS----------QEHFSPAWFLLENHLATSFEDLKAGLSYLKRKVESQKEGQLSFLKSNAGSVIDQLDTLMNIRDKLQEDVKLHGN-ETLNILETSIENSISESQKIFTDVLVRKEKADSTR-SVLFALSRHKFLFCLPNSVDRRAKAGEYDIVVNDYSRAKNLFGKTEIPIFRKVLEEVDHRILSIRKQLHEKVVKMPQSVEQQKKLIKALISLELQ--------------------QSGTPIGD---KLRNIDPAWDAIEARAKYLEWT--FRQTFDQHTSKDSGAQEKAKNRDSS--QAPNRVN--FCEELCDIAASQLPDLWRLGQLYFTGELRGPHDPKPGDFKRMVLNAIEKFCVYLRLAILIATDQRALRQSSGLAWPIGSAS---------ATHQFLP---------WIPQCLRFTRIAYATLISLD-LPSEALDIIQKLIDEVRLFCFSIIFKRATDRCKKLGSQETWELG-----VEEYPGATLLPAALETLLIETLDEVQSVCMQRETREGNLLEPQSDGQREVTQRLQEFLSAFSAVIEELAFHSHDEETPTHNVSQLLGFPNAQQPDSVAGSGGAAAVTWEQRMLCCLANYAYCNKIFFPRLGDIFVRYGYPLPTLAIETA-----RYTVNQLFTNLLEEYVEHKGDPLVGTIEPSMYLGRFQWDHEMEIGQLRPYAHECCDNLVGVYSEIYSISPALLRPILESIVQTISEELARLMS-----CVQRFSFTGAIQAHVDIRLLRDSLEGYVNETAKNYFMEALEAINPPLSG-------------------------------EQK------RKADEILERVKRNMRLQLLCFSVKDP---------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8S3U9-1", "uniprot_id": "SEC5A_ARATH", "id": "Q8S3U9-1", "name": "Exocyst complex component SEC5A", "aln": "MSSDSNDLDEDELLQMALKEQAKRDLTYQKPPSSSARKPVANLVQQPRQQKPVAAAAAPPKKSAA---AVRKPSMDEDEESEVELLSISSGDDDLEREREIGGSSGGAGRGRGSDVREKGRARKEDDGAWDGGEPDCWKRVNEAELARRVRDMRESRTAPVVQKVEGKAPAPGKKVALTSLQSLPRGMECIDPLKLGIIDNKTLRLITESSGSPSKAEKVDNTLREKLVYFSDHFDPKLFLSRIHQDTTAADLEAGALGLKSDLKGRNLQRKQLVKDNFDCFVSCKTTIDDIESKLKR-IEEDPEGSGTTHLFNCMKSVTSRANLAFEPLFERQAQAEKIR-SVQGMLQRFRTLFNLPSIIRSSISKGEYDLAVREYKKAKSIALPSHVNILKRVLEEVEKVMLEFKGTLYKSMEDPKIDFTSLENTVRLLLELEPESDPVWHYLNVQNHRIHGLLEKCTYDHEARVEILRNDTHEKAISDAKWQQIQQN--GVSYSDTASSNENNAVQVDLQSVEFPSEEIDILKGRYIKRLTAVLVHHIPVFWKTAISIFSGKFAKSSQVTDTSANKAEEKVTEAR--------YSTHSLEEVAGMIRKTISVYEAKVNSTFCDFDESCILRP---------FMSDAINEVSKACQAFEAKESTPHSAVVALRKIQAEITKIYIQRLCSWMRASTEGISKEETWIPVSILERNRSPYAISYLPLAFRSVIVSGMEQVNLMILSVKSEAAKSEDMFAQIEEIIISVRLAFLNCFLDFAAHLEQIGADLSQSTSRQDNWKNGYSDEHQEEPSANTYGSVIDPHRRLLMVLSNIGYCKDELASELYNKFKYTWLQSRDKNEDSSDLQDLIMSFSGLGEKVLEHYTFAKANLIRTAATNYLLDSGIQWGSAPQVKGIRDAAVELLHTLVAVHAEVFAGAKPLLDKILGVLIEGLIDTFLSVVEENRSSDLRSIDANGFCQLMFELEYFETVLYSYFTSAATESLKSLQGTVLEIAIESISEAVETPGHNRRPTRGSEDTVSDDKQSVSADDLLALTKQCSNELLQQELERTRVNTACFAESAPLESTPPLPKATYSSFRGSMDSPSRNYRGSQSSGSPINARPRRR--------", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "P89102-1", "uniprot_id": "SEC5_YEAST", "id": "P89102-1", "name": "Exocyst complex component SEC5", "aln": "--MDRFQIGDEQLLRFYQLKTINPTHSWAQDSSKLNNEEATSNELGVETSFDILKDFKYGNQISIDKESRAYLNDESLSYIRDPLNGQEMSKELQHLPNDSMRLNYLVNS---KQFNVKAFLRDMHKQDSFNDLNNSLDRLDSDIQDQS----IHLKQLVGKNFTKYVKIKNKLDQIYKEFDEKTN--------EKNQCDSPKENQINVESLNKKVDEVIR----------TTTFKLKPLMDNYQKILNYQATKKFIELNKFYFNLPKSLKRCLTNNDFNEFIIEYSKGLTLRRRFNQSSDASQSLVIKRIWTQIENLLVTYKDLIWNSLINSNFNIDQPQETILSLFSKLLNLENFINNNQRESESGNKNTTSSSNENPILRWMSIKMNGFQNELNELSGHMISKIIHSQRLILQNNTNQDKSQGCVELSYYLKIN--QLFQIISDTGKDSEGLKSTVEPNKVN---TISGTSYLNLNCQPSSQGLTDSPTIIEMWLLILKYINDLWKICDQFIEFWEHIEKFLDG---TYQNSIINEKRKENILIGDSNIIESYQKSLILKEEQINEVRLKGEEFITSVSQNLISFFTSSQSSLPSSLKDSTGDITRSNKDSGSPLDYGFIPPNCNGLSCLRYLPKIVEPILKFSTELAQLN-ITTNGITICRNTLSTIINRCVGAISSTKLRDISNFYQLENWQVY-------ETVTFSSKSQDSSKNLTFEYGVTQFPEIVTSFQEVSIKTTR---DLLFAYEKLPIINGISVVSYPSKQLLTGIEIQQIISMEAV------LEAILKNAAKDKDNPRNSHTILTLTNLQYFRECAFPNILQYFDDAFEWNLASKNLEL-----FSLLSKMESSIFGNYLSDLKINLRDTLEEKFHEINWPMYTSNSFR-VGDYIIEALMILIVVHSECFRIGPQLIHKILIETQIFIARYLFEAFKP----YVGNLSNDGSLQIIVDLEFFQKVMGPLLEKDTEATLRACLQNCFQNDTN-------------------------------------RLQKCINEINPIVSANLKRTAIQFAAFS----------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : : * . : . *. . . . : . . :. : . : . : * : . :.. . .. :. ::: . : . : : :: : : :. : . :.: * : . *: : . . ... .: ::. *:. : : . . : :. *. . . . . . . : : : . . . :. : : ::.. :. : : . . : :. : . . . : . * * . : . : . . : . ::. : : . : : *:* * . .: : * .. : :: * : : : : * :: *::* : *: :: : : .. : :. * * .:: :. : . : : * : ", "identical_positions": 21, "similar_positions": 165, "identity": "1.87%" }, { "cls_id": "homologset.oma.815573", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A1L1L2-1", "uniprot_id": "TM214_RAT", "id": "A1L1L2-1", "name": "Transmembrane protein 214", "aln": "MAARAAGSGGWEVVKRSRRPGASSGGRGGGG--DRRALGEANGVWKYDLSSPIQPTSTLYERGFEKIMKRQNKEQVPPPAAES-KKPVNKKQPKKV-TAVASQNQKQGPFRSLEDALKALDVAALQKELDKSQSVFTGNPSVWLKDLASYLNYKLQTPRMEPTLSQYPHDYPYSLVSRELRGIIRGLLTKAAGSVELFFDHCLFTMLQELDKTPGESLHGYRICIQAILQDKPKIVTSNLDKFLELLRSHQSRPAKCLTIMWALGQAGFTNLTEGLKVWLGIMLPVLGIKSLSPFAIAYLDRLLLMYPN-LTKGFGMIGPKDFFPLLDFAYMPNNSLSPSLQEQLCQLFPRLKVLAFGAKPESSLHTYFPSFLSRATPSCPAAMKKELLASLTQCLTVDPLSTSVWRQLYPKHLSQSSLLLEHLLTSWEQIPKKARKC------------LQETIQSFTLTN-------QELLKKGSGSNEHVVTCDTACKGLLQQARGPRPPWARLLLLLLVFAVGFLCHDLRSHSSFQASLTGRLLQSSGLLPVAQQVCAKLYSYSLQSYNWLQETLPACGSYLLAVVQPSLQLAWTYIYATFSFLSAYCASYLAFFSDSLAGVLQR--VQLPEALHQLFHSLKELLLLFYHSVLLPMWHLLLAALAQVQEHCHEACRGEMTWDCIKTQFSTAAHWTWLCLQDVTVAFLDWALTMISQQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BM55-1", "uniprot_id": "TM214_MOUSE", "id": "Q8BM55-1", "name": "Transmembrane protein 214", "aln": "MAARSAGSGGWEVVKRGRRPGASSGGRGGGGGSDRRALGEANGVLKYDLSSPIQTTSTLYERGFEKIMKRQNKEQVPPPAAES-KKPINKKQPKKV-TAVPSQNQKQGPFRRLEDALKALDVAALQKELDKSQSVFTGNPSVWLKDLASYLNYKLQTPRMEPTLSQYPHDYPYSLVSRELRGIIRGLLTKAAGSVELFFDHCLFTMLQELDKTPGESLHGYRICIQAVLQDKPKIVTSNLDKFLELLRSHQSRPAKCLTIMWALGQAGFTNLTEGLKVWLGIMLPVLGIKALSPFAIAYLDRLLLMHPN-LTKGFGMIGPKDFFPLLDFAYMPNNSLSPSLQEQLCQLFPRLKVLAFGAKPESSLHTYFPSFLSRATPSCPAAMKKELLASLTQCLTVDPLSTSVWRQLYPKHLSQSSLLLEHLLKSWEHIPKKARKS------------LQETIQSLKVTN-------QELLKKGSGGSEHVLTCDTACKGLLQRARGPRPPWARLFLLLLVFAVGFLCHDLRSNSSLQASLTGRLLRSSGLLPVGQQVCARLSSYSLQSYNWLQETLPACGSHLLAVVQPSLQLAWTHIYAIFSFLSAHCASYLACFSDSLAGFFQR--VQLPEALQQLFHALKELLLLFCHSVLLPTWHLLLAALAQVQEHCHEACRGDVTWDCIKTQLSRAAQWTWLCLQDVTVAFLDWALTMISQQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8C2MYY7-1", "uniprot_id": "A0A8C2MYY7_CRIGR", "id": "A0A8C2MYY7-1", "name": "", "aln": "MAARAAGSGGWEVVKKGRRPGASGGGRGVGG-SDRRALGEANGVWKYDLSSPIQTTSTLYERGFEKIMKRQNKEQVPPPVVES-KKPGNKKQPKKV-TAVTSQNQKQGLFRSLEDALKALDVAALKKELDKSQSVFTGNPSVWLKDLASYLNYKLQTPRIEPTLSQYPHDYPYSLVSQELRGIIQGLLTKAAGSVELFFDHCLFTMLQELDKTPGESLHGYRICIQAILQDRPKIVTSNLGKFLELLRSHQSRPAKCLTIMWALGQAGFANLTEGLKVWLGIMLPVLGIKSLSPFAIAYLDRLLLMHPN-LTKGFGMIGPKDFFPLLDFAYMPNNSLTPSLQEQLCQLFPRLKVLAFGAKPESTLHTYFPSFLSRATPSCPAEMKRELLGSLTQCLTVDPLSTSVWRQLYPKHLSQSSLLLEHLLKSWERIPKKARKS------------LQETIQSFKLAN-------QELLKKGSGGNEHVVTCDAACKGLLQQARGPRPPWARLLLLLLVFAVGFLCHDFRSHGSFQASLTGWLLRSSGFLPVGQHLCAKLYSCSIQSYSWLQETLPAYGSHLLAVIQPSLQLAWTHTDATVSFLSAHCASYLAYFGDSLAGFLQR--VQLPEALHQLLHSLKDLLLLFYHSVLLPLWHLLLAALARAQEHCHQACRGEVTWDCIKTQFGEAARWTWLCLQDVTVAFLDWALAMISQQ", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q6NUQ4-1", "uniprot_id": "TM214_HUMAN", "id": "Q6NUQ4-1", "name": "Transmembrane protein 214", "aln": "MATKTAGVGRWEVVKKGRRPGVGAGAGGRGGGRNRRALGEANGVWKYDLTPAIQTTSTLYERGFENIMKRQNKEQVPPPAVEP-KKPGNKKQPKKV-ATPPNQNQKQGRFRSLEEALKALDVADLQKELDKSQSVFSGNPSIWLKDLASYLNYKLQAPLSEPTLSQHTHDYPYSLVSRELRGIIRGLLAKAAGSLELFFDHCLFTMLQELDKTPGESLHGYRICIQAILQDKPKIATANLGKFLELLRSHQSRPAKCLTIMWALGQAGFANLTEGLKVWLGIMLPVLGIKSLSPFAITYLDRLLLMHPN-LTKGFGMIGPKDFFPLLDFAYMPNNSLTPSLQEQLCQLYPRLKVLAFGAKPDSTLHTYFPSFLSRATPSCPPEMKKELLSSLTECLTVDPLSASVWRQLYPKHLSQSSLLLEHLLSSWEQIPKKVQKS------------LQETIQSLKLTN-------QELLRKGSSNNQDVVTCDMACKGLLQQVQGPRLPWTRLLLLLLVFAVGFLCHDLRSHSSFQASLTGRLLRSSGFLPASQQACAKLYSYSLQGYSWLGETLPLWGSHLLTVVRPSLQLAWAHTNATVSFLSAHCASHLAWFGDSLTSLSQRLQIQLPDSVNQLLRYLRELPLLFHQNVLLPLWHLLLEALAWAQEHCHEACRGEVTWDCMKTQLSEAVHWTWLCLQDITVAFLDWALALISQQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4FV45-1", "uniprot_id": "TM214_BOVIN", "id": "A4FV45-1", "name": "Transmembrane protein 214", "aln": "MAAKTAGGGRWEVVKKGRRP--GAGGSGKGGGGDRRALGEANGVWKYDLTPPIQTTSTLYERGFEKIMKRQNKEQVPPPAVEP-KKPGNKKQAKKV-ATLTNQNQKQGRFRSLEEALKALDLADLQKELDKSQSVFSGNPSVWLKDLASYLNYKLQVPPSEPTLSQHPHDYPYSLVSRELRGIIRGLLAKAAGSLELFFDHCLFTMLQELDKTPGESLHGYRICIQAILQDKPKIVTTNLGKFLELLRSHQSRPAKCLTIMWALGQAGFTNLTEGLRVWLGIMLPVLGIKSLSPFAIAYLDRLLLMHPN-LTKGFGMIGPKDLFPLLDFAYMPNNSLTPSLQEQLCQLYPRLKVLAFGAKPESTLHTYFPSFLSRATPGCPLEMKKELLRSLTECLMVDPLSTSVWRQLYPKHLSQSSLLLEHLLRSWERIPKKTQKS------------LQETIQSFKLTN-------QDLLRKGGGSNQDVVTCDSACKSLLQQARGFQLPWTRLLLLVLVFAIGFLCHDFRSHSSFQASLSGQLLQSSGVLPAGQQACTKIYSYSLQGYSWLEKTLPAWGSHLLTVVRPGLQLAWAHTNATVGFLSAHCASHLAWFGDSLANLFQRLQTQLPDTLNQLLRSLRELLLFLYHSILLPTWHMLLEALAQIQEHCHEACRGEVTWDCMKTQLSEAAHWTWLRLQDTTVAFLDWALAMISQQ", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1QEL0-1", "uniprot_id": "F1QEL0_DANRE", "id": "F1QEL0-1", "name": "", "aln": "---MASGVGKWEVVKKGKKATSSSKTQDKKS--ARKALREAN------TDSNHVMSETIFD-GFEKMVKKQNKEQVPPPVETQQKKPNAGKQTKKP-PANSSP--KPVHYKTLEEAVKALNIAELKQQLEKSQTLFPENPSIWVKDLAGYLNYKLPAPDTDPTLSSYAHDYPYCLAGKELKAIIKNLLGKCSDALPEFFDHCVFTMLREQDRQPSDPLHGYRMCIQALMQDKPKIATLNLSDHLELLRSHQNRPLKCLTIMWALGQAGFYDLSQGIRVWLGIMLPVLGMKALSAYAIAYLERLLTLHAN-LTKGFGIMGPKEFFPLLDFAYMPKNALSQSLQEQLCRLYPRIKVLAFGAKPESTLHTYFPSFLSRATPNCPGAMKKELLRSLTECLSVDSQSLSVWRQLYTKHLPQSSLLLNHLLKTWKTLPLKLQKS------------LQDTIQSFRVTN-------DELQS--GAHTQEISDCNSLCQSLQLKMHGQSVPWWRVLLMLLVCVLGFVAHDVRTQGSFSDSRTAVFLEQLGVSGASQQAWSRVSHYSQQSLSWLSENTPYYYSSAVTAVRPLLEYGQEYVKLAVLKIAHMSSELMLWMQENLPLLLHWIHANTPESVFQFLEFLKGLLLFVHEQMILPALHYLNTALQLAWRSLQESCNGEVSLHCLQDHVRSFTNSTWIYLQDATSAIKSRAQELLS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKM7-1", "uniprot_id": "Q9VKM7_DROME", "id": "Q9VKM7-1", "name": "", "aln": "------MSEQWEVVSKSRKQKNLDKKVSAHNEQKRIAAQLPKLEELLPTQRYRNLFGSSNNNNSKSHSPAKSSSSASSSSKAN-KSPVKKHTAKNASTQKRTTSAAASKPKTLELALRNITRDDFAAQLEQVKLSCPGSELRWLSHIALYFNEALSY-DCDPIFSGRSAQYPSNLASASLKYSIVEFLGSVGEQNLEYFFYSLLDSMS-TDLNNNQTVAGYKLILQLIGQNWPNICSRNLAKTALLRNSYQNRSNICLSILWAIGQGGYQSLNEGVRVWQNLMLPNLELKQYTKFVVEYMERALSAAAVRKTADPLQINQQEFFATYNALNAPYNHLPKEWQQSLKRS-ARLLLQHYINSPVRHANIFLTLFREISAGSKQTNEIEGCISCLLSSGRDD--CLRVWRMNYKKQQLPSLLLLKAINDNWTTSTHELATSTVYHSFLQDVANLNEELQGSKRNEGHLDDLKEVLLSVQEKSSAQQKKNKQKAAAEKKKCGCCKWTLGSIFIIALIAGALYYDTEVNGKGVFEKSATGKVLKNAGVLPHVQKSWYTVMGAGARGYKWAEVNVPPYAEPVIKTTCDLWKLARN-------AACNAYQNGKGYFGAKWPVVAKFIDQYVPNSSGKIEAFAAGVSDLAAS--------SYEKAAALIKEKVLVGRLSPENINQALNQTRNAALEYYNQFHKKVDAYAKLK-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****.:.:: . . * * .: : : . :. :........ *.* : .*: . . : ** *:: : : :*:: : . . *:..:* *:* * :* :* . :** *.. .*: * :* . . :* :.:: : * .:.: **:: :* : *: *:* : ** . * .*:*.*. **:*:**:**.*: .*.:*::** .:*** * :* : :.: *::* * . * . :. :::*. : * * *. . *:.* : .*: : : .* : ::. * . :: . . : .* .. * . *** * *: * ***: : .* . : .. *:: :*. : : * . . . . . : . :::: *: : :.. :. :. * :. .*.. *. *: : . :. .* . * . : . : . . . : . . . : *:: :: : : * . . . . . : . : ::. . * . ", "identical_positions": 95, "similar_positions": 208, "identity": "13.36%" }, { "cls_id": "homologset.oma.815597", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CPT4-1", "uniprot_id": "MYDGF_MOUSE", "id": "Q9CPT4-1", "name": "Myeloid-derived growth factor", "aln": "MAAPSGG--------FWTAVVLAAAALKLAAAVSEPTTVPFDVRPGGVVHSFSQDVGPGNKFTCTFTYASQGGTNEQWQMSLGTSEDSQHFTCTIWRPQGKSYLYFTQFKAELRGAEIEYAMAYSKAAFERESDVPLKSEEFEVTKTAVSHRPGAFK-AELSKLVIVAKAARSEL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZTQ0-1", "uniprot_id": "A0A8I5ZTQ0_RAT", "id": "A0A8I5ZTQ0-1", "name": "", "aln": "MAAPSSG--------FWTALVLAAAALKLAAAVSEPTTVPFDVRPGGVVHSFSQDIGPGGKFTCTFTYASQGGTNEQWQMSLGTSEDSQHFTCTVWRPQGKSYLYFTQFKAELQGAEIEYAMAYSKAAFERESDVPLKSEEFEVTKTAVSHRPGAFK-AELSKLVIVAKAAHSEL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q969H8-1", "uniprot_id": "MYDGF_HUMAN", "id": "Q969H8-1", "name": "Myeloid-derived growth factor", "aln": "MAAPSGGWNGVG-ASLWAALLLGAVALRPAEAVSEPTTVAFDVRPGGVVHSFSHNVGPGDKYTCMFTYASQGGTNEQWQMSLGTSEDHQHFTCTIWRPQGKSYLYFTQFKAEVRGAEIEYAMAYSKAAFERESDVPLKTEEFEVTKTAVAHRPGAFK-AELSKLVIVAKASRTEL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62248-1", "uniprot_id": "MYDGF_BOVIN", "id": "P62248-1", "name": "Myeloid-derived growth factor", "aln": "MAAPSGRRNGSGGANLWVSLLLAAAALRPVETVSEPTTVAFDVRPGGVVHSFSQNVGPGDKYTCVFTYASQGGTNEKWQMSLGTSEDHQHFTCTIWRPQGKSYLYFTQFKAEVRGAEIEYGMAYSKAAFEKESDVPLKNEEFEVTKTAVFHRPGAFK-AELSKLVIVAKATRSEL----", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A9J7G267-1", "uniprot_id": "A0A9J7G267_CRIGR", "id": "A0A9J7G267-1", "name": "", "aln": "MAAPSGA--------FWTALLLVAAALTLAAAVSEPTTVPFDVRPGGVVHSFSQDVGPGGKFTCTFTYASQGGTNEQWQMSLGTSEDSQHFTCTIWRPQGKSYLYFTQFKAELRGAEIEYAMAYSKAAFERESDVPLKNEEFEVTKTADQKLSGEWSGLKTSHLQDDRMDPVLQLLLSV", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****. :*.:::* *.** . :*******.*************:::***.*:** ***********:********** ******:*****************::******.*********:*******.********* : .* :. : *:* . :* ", "identical_positions": 115, "similar_positions": 30, "identity": "64.25%" }, { "cls_id": "homologset.oma.815609", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P0DKR2-1", "uniprot_id": "TCAIM_RAT", "id": "P0DKR2-1", "name": "T-cell activation inhibitor, mitochondrial", "aln": "MLGSWRAFSEMFCHLRPWRRFCLRKVLPPWLHYSRALSGAEAINALRPFYFAVHPDFFGQHPREREVNENSLKRLSVYLENLQKPGFKSLKPTQLTFYIREKTAQNSSEGQEPVSTTGFRAVRFTLHSSDLLSTVLYILNSCSLPVEHVQSLNTNVHSQPLKEATGMPDRPIKWHRSYYSFTGFKDPDEDLEHVSRVETTLTSWLGSNGKGAVKKLKNSLPLRKELDRLKNELSELLQLSDIRWQRGWGVAHRCSQLHSLSRLAQQNLEPLQNAKGCTIVFTDRSGMSALGHVMLGTMDVHHHWTRLFESLPNYFDLQRRMSALEDQISHLLGGIQVVY--IEELQPALTLDEYYSLLDTFYNQLQRSRAPPR--PQSLSGLQMILS--RYAPSLHELGHFNIPALSDPASLQSFMRTKAQQARENMRRREKLKVIENELIQASTRKFSLEKLYKEPSISSRQMVDCCKRLLEQSLPYLHGMHLCVSHFYSVMQDGDLCIPWNWKKGEAMK--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q66JZ4-1", "uniprot_id": "TCAIM_MOUSE", "id": "Q66JZ4-1", "name": "T-cell activation inhibitor, mitochondrial", "aln": "----------MFCHLRPLRRFGLRKVLPHWLHYSRALSGAEAINALRPFYFAVHPDFFGQHPREREVNENSLKRLSVYLENLQKPGFKSLKPTQLTFYIREKTAQNSSEGQEPISTTGFRAVRFTLHSSDLLSTVLYILNSCSLPVEHVQSLNTNVHSQPLKEATGMPDRPIKWHRSYYSFTGFKDPDEDLTHVSRVETTLTSWLGSNGKGAVKKLRNSLPLRKELDRLKNELSELLQLSDIRWQRGWGVAHRCSQLHSLSRLAQQNPGPLQNVKGCTVVFTDRSGMSALGHVMLGTMDVHHHWTRLFESLPSYFDLQRRMSALEAQISNLLGGIQVVY--IEELQPALTLDQYYSLLHTFYNQLLRSRVPPHPHPQSLSGLQMILSSDRYAPSLHELGHFDIPALSDPASLQSFMRTKAQQARENMTRREKLKVMENELIQASTKQFSLEKLYKEPSISSRQMVDCCKRLLEQSLPYLHGMHLCVSHFYSVMQDGDLCIPWNWKKGEAMK--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E1BM88-1", "uniprot_id": "E1BM88_BOVIN", "id": "E1BM88-1", "name": "", "aln": "----------MFCHLRPVRRLCPGKILPYCFLLSRALSGAEAVNALRPFYFAVHPDFFGQHPREREVNENSLKRLSAYLENLQKPGFKSLKPTQLVFYVRE-TDQNPSDGQEHFSTSGFRAVKFTLHTRDLLSTVLYILNSCSLSIEHVQSLNTNVHSQPLKEAKRTSDRPIKWDKSYYSFTGFKDPDEDLEQVWRTETTLTSWLDNNGESAVKKLKNSLPLRQELDRLKDELSHQLQLSDIRWQRSWGIAHRCSQLHSLGRLAQQNLETLKNAKGCTIIFTDRSGMSAVGHVMLGTMDVHHHWTKLFERLPSYFDLQRRLTHLEDQISYLLGGIQVVY--IEELQPVLTLEEYYSLLDVFYNRLLKSRIPFH--PRSLRGLQMILNSDRYAPSLHELGHFNIPVLCDPANLQWFILTKAQQARENMKKREELKVIENELMQASTKKFCLEKFYKEPSVSSIQMVDCCKRLLEQSLPYLQGMHLCISHFYSVMQDGDLCIPWNWKNGEAIK--------", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A287ADZ0-1", "uniprot_id": "A0A287ADZ0_PIG", "id": "A0A287ADZ0-1", "name": "", "aln": "----------MFCHLRPMRRLCLGKIFPYWFLCSRALSGAEAVNALRPFYFAVHPDFFGQHPREREVNENSLKRLSAYLENLQKPGSKSLKPTQLMFYVRE-TDQNSSEGQEHFTTSGFRAVKFTLHTRDLLSTVLYILNSCSLSVEHIQSSNTNVHSQPLKKAQRMSDRPIKWDKSYYSFTGFKDPDEDLEQVWRMETTLTSWLDNNGKSAVKKLKNSLPLRKELSRLKDELSHQLELSDIRWQRSWGIAHRCSQLHSLGRLAQQNLETLKNAKGCTIIFTDRSGMSAVGHVMLGTMDVHHHWTKLFERLPSYFDLQRRLMLLEDQISYLLGGIQVVY--IEELQPVLTLEEYYSLLDVFYNRLSKSRIPFH--PRSLRGLQMILNSDRYAPSLHELGHFNIPTLCDLANLQWFILTKAQQARENMKRKEELKVMEHELMQASTKKFSLEKFYKEPSVSSMQMVDCCQRLLEQSLPYLQGMHLCVSHFYSVMQDGDLAFLGIGRVEKPLNNTEICIPF", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q8N3R3-1", "uniprot_id": "TCAIM_HUMAN", "id": "Q8N3R3-1", "name": "T-cell activation inhibitor, mitochondrial", "aln": "----------MFCHLRPMRRLCLEKIFPHWFPFSRALSGAEAVNALRPFYFAVHPDFFGQHPVEREINENSLKRLSVYLENLQKPGFKSLKPTQLTFYVRE-TDQSSSDGQEPFSTSGFRAVKFTLHTRDLLSTVLYILNSCSLSVEHIQSLNTNMHTQPLKEAKRMPDRPIKWDKSYYSFTGFKDPDEDLEQVSRVETTLTSWLDNNGKSAVKKLKNSLPLRKELDRLKDELSHQLQLSDIRWQRSWGIAHRCSQLHSLSRLAQQNLETLKKAKGCTIIFTDRSGMSAVGHVMLGTMDVHHHWTKLFERLPSYFDLQRRLMILEDQISYLLGGIQVVY--IEELQPVLTLEEYYSLLDVFYNRLLKSRILFH--PRSLRGLQMILNSDRYAPSLHELGHFNIPTLCDPANLQWFILTKAQQARENMKRKEELKVIENELIQASTKKFSLEKLYKEPSISSIQMVDCCKRLLEQSLPYLHGMHLCISHFYSVMQDGDLCIPWNWKNGEAIK--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRT6-1", "uniprot_id": "Q9VRT6_DROME", "id": "Q9VRT6-1", "name": "T-cell activation inhibitor, mitochondrial", "aln": "-----------MSMSLGSKIRKLVTSRRHFLLLRRSLN-QDLTTALRPFYFAVHPDFFAQHPEQRNTNENSLKLLSEHLEALYERRQRSGDTQVLKFYVRTSSDADKRDSFKLIQIR-----TDWQSTRDPKTFIQGLLESCNLSTEYVKNIKAQPEPPKTSGLDFKPSHDYHYDMEFAEFETQLKNER-----ASKRPVLTTWLEENAGTAKQRSKETADLQAEIDKLKKMLVEKLELQDARYECGWNIEHYRGCLKTLERLSNTHLLEMASLKGRIVVFAPFTGISLEGHVMLFTGDVLSTWIDFIKNIPHHDAYLKVVPVYERTLSQVLLNIQIGRRKFMPKQQASGYASYLMKVTTSLSDYLGKQKYPPEWPKTLKEFTIVVESEAGPLMVSPTGQFITPATCPGSILVDFISVNLELARERMKKYAQDKHIEQELMDSCIKQLQLQSLTKDDAITPDKMITSLRDLYQLQLKELQGCKLHITHYYSVLTDGVVCIPWDFLQR------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : . : *:*. : .**************.*** :*: ****** ** :** * : :* .. * **:* : . :. : . : * : : :*:**.*. *:::. ::: .. . ..: ::. .: .* . :. ...**:** .*. * :: ::: *: *:.:**. * . *:*.* *:: .*.: * . *::* **:: : : . ** ::*: :*:* ***** * ** * ::: :* : : : * :* :* .**: : * . .* : . . .: *::* : :::. . : *:* *. . : * *: .: : ***.* : : * :*:**:::. ::: *:.: *: :::. :*: . : * : .* *:* :* ::*:***: ** :.: ", "identical_positions": 115, "similar_positions": 161, "identity": "22.16%" }, { "cls_id": "homologset.oma.815618", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADS9-1", "uniprot_id": "D4ADS9_RAT", "id": "D4ADS9-1", "name": "Protein EFR3 homolog A", "aln": "MPTRVCCCCSALRPRYKRLVDNIFPEDPKDGLVKADMEKLTFYAVSAPEKLDRIGAYLAERLSRDVVRHRSGYVLIAMEALDQLLMACHSQSIKPFVESFLHMVAKLLESGEPKLQVLGTNSFVKFANIEEDTPSYHRRYDFFVSRFSAMCHSCHSDPEIRTEIRIAGIRGIQGVVRKTVNDELRATIWEPQHMDKIVPSLLFNMQKIEEVDSRLGPPSSPSAADKEENPAVLAESCFRELLGRATFGNMNNAVRPVFAHLDHHKLWDPNEFAVHCFKIIMYSIQAQYSHHVIQEILGHLDARKKDSPRVRAGIIQVLLEAVAIAAKGSIGPTVLEVFNTLLKHLRLSVELEASDSQKGSVG--SVSLSSKDNDEKIVQNAVIQTIGFFGSNLPDYQRSEIMMFIMGKVPVFGTSTHTLDISQLGDLGTRRIQIMLLRSLLMVTSGYKAKTIVTALPGSFLDPLLSPSLMEDYELRQLVLEVMHNLMDRHDNRAKLRGIRIIPDVADLKIKREKICRQDTSFMKKNGQQLYRHIYLGCKEEDNVQKNYELLYTSLALITIELANEEVVIDLIRLAIALQDSAIINEDNLPMFHRCGIMALVAAYLNFVSQMIAVPAFCQHVSKVIETRTMEAPYFLPEHIFRDKCMLPKSLEKHDKNLYFLTNKIAESLGGSGYSVERLSVPYVPQVTDEDRLSRRKSIVDTVSIQVDILSNSVPSDDVVSNTEEITFEALKKAIDTNGMEEQEKEKRRLVIEKFQKAPFEEIAAQCESKANLLHDRLAQILELTIRPPPSPSGTLTVTSGHAQYQSVPVYEMKFPDLCVY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG67-1", "uniprot_id": "EFR3A_MOUSE", "id": "Q8BG67-1", "name": "Protein EFR3 homolog A", "aln": "MPTRVCCCCSALRPRYKRLVDNIFPEDPKDGLVKADMEKLTFYAVSAPEKLDRIGAYLAERLSRDVVRHRSGYVLIAMEALDQLLMACHSQSIKPFVESFLHMVAKLLESGEPKLQVLGTNSFVKFANIEEDTPSYHRRYDFFVSRFSAMCHSCHSDPEIRTEIRIAGIRGIQGVVRKTVNDELRATIWEPQHMDKIVPSLLFNMQKIEEVDSRLGPPSSPSAADKEENPAVLAESCFRELLGRATFGNMNNAVRPVFAHLDHHKLWDPNEFAVHCFKIIMYSIQAQYSHHVIQEILGHLDARRKDSPRVRAGIIQVLLEAVAIAAKGSIGPTVLEVFNTLLKHLRLSVELEANDSQKGSVG--SVTVSSKDNDEKIVQNAVIQTIGFFGSNLPDYQRSEIMMFIMGKVPVFGTSTHTLDISQLGDLGTRRIQIMLLRSLLMVTSGYKAKTIVTALPGSFLDPLLSPSLMEDYELRQLVLEVMHNLMDRHDNRAKLRGIRIIPDVADLKIKREKICRQDTSFMKKNGQQLYRHIYLGCKEEDNVQKNYELLYTSLALITIELANEEVVIDLIRLAIALQDSAIINEDNLSMFHRCGIMALVAAYLNFVSQMIAVPAFCQHVSKVIETRTMEAPYFLPEHIFRDKCMLPKSLEKHDKNLYFLTNKIAESLGGSGYSVERLTVPYVPQVTDEDRLSRRKSIVDTVSIQVDILSNSVPSDDVVSNTEEITFEALKKAIDTNGMEEQEKEKRRLVIEKFQKAPFEEIAAQCESKANLLHDRLAQILELTIRPPPSPSGTLTVTSGHTQYQSVPVYEMKFPDLCVY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AAA9T2Q2-1", "uniprot_id": "A0AAA9T2Q2_BOVIN", "id": "A0AAA9T2Q2-1", "name": "Protein EFR3 homolog A", "aln": "MPTRVCCCCSALRPRYKRLVDNIFPEDPKDGLVKADMEKLTFYAVSAPEKLDRIGSYLAERLSRDVVRHRTGYVLIAMEALDQLLMACHSQSIKPFVESFLHMVAKLLESGEPKLQVLGTNSFVKFANIEEDTPSYHRRYDFFVSRFSAMCHSYHSDPEIRTEIRIAGIRGIQGVVRKTVNDELRATIWEPQHMDKIVPSLLFNMQKIEEADSRIGPPPSPSAADKEENPAVLAENCFRELLGRASFGNMNNAVRPVFAHLDHHKLWDPNEFAVHCFKIIMYSIQAQYSHHVIQEILGHLDACKKDSPRVRAGIIQVLLEAVAIAAKGSIGPTVLEVFNTLLKHLRFSVELEANDLQAGSTGNANVDTSSKDSDEKMVQNAVIQTIGFFGSNLPDYQRSEIMMFIMGKVPVFGTSTHTLDISQLGDLGTRRIQIMLLRSLLMVTSGYKAKTIVTALPGSFLDPLLSPSLMEDYELRQLVLEVMHNLMDRHDNRAKLRGIRIIPDVADLKIKREKICRQDTSFMKKNGQQLYRHIYLGCKEEDNVHKNYELLYTSLALITIELANEEVVIDLIRLAIALQDSAIINEDNLPMFHRCGIMALVAAYLNFVSQMIAVPAFCQHVSKVIEIRTMEAPYFLPEHIFRDKCMLPKSLEKHDKNLYFLTNKIAESLGGSGYSVERLSVPYVPQVTDEDRLSRRKSIVDTVSIQVDILPNSIPSDDVVSNTEEITFEALKKAIDTSGMEEQEKEKRRLVIEKFQKAPFEEIAAQCESKANLLHDRLAQILELTIRPPPSPSGTLTITSGHAQYQSVPVYEMKFPDLCVY", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q14156-1", "uniprot_id": "EFR3A_HUMAN", "id": "Q14156-1", "name": "Protein EFR3 homolog A", "aln": "MPTRVCCCCSALRPRYKRLVDNIFPEDPKDGLVKTDMEKLTFYAVSAPEKLDRIGSYLAERLSRDVVRHRSGYVLIAMEALDQLLMACHSQSIKPFVESFLHMVAKLLESGEPKLQVLGTNSFVKFANIEEDTPSYHRRYDFFVSRFSAMCHSCHSDPEIRTEIRIAGIRGIQGVVRKTVNDELRATIWEPQHMDKIVPSLLFNMQKIEEVDSRIGPPSSPSATDKEENPAVLAENCFRELLGRATFGNMNNAVRPVFAHLDHHKLWDPNEFAVHCFKIIMYSIQAQYSHHVIQEILGHLDARKKDAPRVRAGIIQVLLEAVAIAAKGSIGPTVLEVFNTLLKHLRLSVEFEANDLQGGSVGSVNLNTSSKDNDEKIVQNAIIQTIGFFGSNLPDYQRSEIMMFIMGKVPVFGTSTHTLDISQLGDLGTRRIQIMLLRSLLMVTSGYKAKTIVTALPGSFLDPLLSPSLMEDYELRQLVLEVMHNLMDRHDNRAKLRGIRIIPDVADLKIKREKICRQDTSFMKKNGQQLYRHIYLGCKEEDNVQKNYELLYTSLALITIELANEEVVIDLIRLAIALQDSAIINEDNLPMFHRCGIMALVAAYLNFVSQMIAVPAFCQHVSKVIEIRTMEAPYFLPEHIFRDKCMLPKSLEKHEKDLYFLTNKIAESLGGSGYSVERLSVPYVPQVTDEDRLSRRKSIVDTVSIQVDILSNNVPSDDVVSNTEEITFEALKKAIDTSGMEEQEKEKRRLVIEKFQKAPFEEIAAQCESKANLLHDRLAQILELTIRPPPSPSGTLTITSGHAQYQSVPVYEMKFPDLCVY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0Y447-1", "uniprot_id": "A0A8V0Y447_CHICK", "id": "A0A8V0Y447-1", "name": "Protein EFR3 homolog A", "aln": "MPARVCCCCAALRPRYKRLVDNIFPEDPKDGLVKADMEKLTFYAVSAPEKLDRIGAYLAERLSRDVVRHRYGYVLIAMEALDQLLMACHSQSIKPFVESFLHMVAKLLESGEPKLQVLGTNSFVKFANIEEDTPSYHRRYDFFVSRFSAMCHSCDHDPETQTEIRIAGIRGIQGVVRKTVNDELRATIWEPQHMDKIVPSLLFNMQKIEDVDSRTGPPSSPTGGEKEENPALLAENCFRELLGRATYGNMNNAVRPVFAHLDHHKLWDPNEFAVSCFKIIMYSIQAQYSHHVIQEILGHLDGCKKDPPRVRAGIIQVLLEAVAIAAKGSIGPTVLEVFNTLLKHLRISVDFELGD-RRSSAGSATFSTSSKENDERIVQNAIIQTIGFFGSNLPDYQRSEIMMFIMGKVPVLGATSQSLDTSHLGDLGTRRIQIMLLRSLLMVTSGYKAMTITNALPAPFLDPLLSPSLMEDSELRQLVLEILHNLIDRHDNRAKLRGIRIIPDVSDLKIKRDKISRQDVSFMKKHGQQLYRHIYLGCKEEDNVQKNFELLYTSLALITIELANEEVVIDLIRLAIALQDVAIINEDNLPMFNRCGIMALVAAYLNFLSQMIAVPSFCQHVSKVIETRSLEASYFLPETIFKDKCNLPKSLEKHEKNLFFLTNKIAESLGGSGYSVERLSVPYVPQVTDEDRLSRRKSIVDTVSIQVDILPGNN-TEDKIDNTEEITFEALKKAIDNNGLEEQEKEKRRLVIEKFQKAPFEEIAAQCETKANLLHDRLAQILELTIRPPPSPSGTMTITAGHAHYQSVPVYEMKFPDLF--", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:******:************************:********************:************** ********************************************************************************** . *** :************************************************:.*** ***.**:. :******:***.*********::*************************** **************************. :**.***************************************:**::* .* : .*.* .. ***:.**::****:*****************************:*:::::** *:************************** **..***..************* ********::***:******************:******:**.***.*****:******************:**:******************************** ********.**:**************:*******:********** *::**.***** **:*** ********:*:*:********************:******************************... ::* :.***************..*:****************************:**************************:*:*:**::************** ", "identical_positions": 711, "similar_positions": 82, "identity": "86.6%" }, { "cls_id": "homologset.oma.815619", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y2G0-1", "uniprot_id": "EFR3B_HUMAN", "id": "Q9Y2G0-1", "name": "Protein EFR3 homolog B", "aln": "---------------MYG-----------VCGCCGALRPRYKRLVDNIFPEDPEDGLVKTNMEKLTFYALSAPEKLDRIGAYLSERLIRDVGRHRYGYVCIAMEALDQLLMACHCQS-INLFVESFLKMVAKLLES-EKPNLQILGTNSFVKFANIEEDTPSYHRSYDFFVSRFSEMCHSSHDDLEIKTKIRMSGIKGLQGVVRKT-----------VNDELQANIWDPQHMDKIVPS--LLFNLQHVEEAESRSPSPLQAPEKE-------KESPAELAERCLRELLGRAAFGNIKNAIKPVLIHLDNHSLWEPKVFAIRCFKIIMYSIQPQHSHLVIQQLLGHLDANSRSAATVRAGIVEVLSEAAVIAATGSVGPTVLEMFNTLLR-----QLRLSIDYALTGSYDGAVSLG-TKIIKEHEERMFQEAVIKTVGSFASTLPTYQRSEVILFIMSKVPRPSLHQAVDTGRTGENRNRLTQIMLLKSLLQVSTGFQCNNMMSALPSNFLDRLLSTALMEDAEIRLFVLEILISFIDRHGNRHKFSTISTLSDISVLKLKVDKCSRQD----------TVFMKKHSQQLYRHIYLSCKEETNVQKHYEALYGLLALIS----IELANEEVVVDLIRLVLAVQDVAQVNEENLPVYNRCALYALGAAYLNLISQLTTVPAFCQHIHEVIETRKKEAPYMLPEDVFVERPRLS-QNLDGVVIELLFRQSKISEVLGGSGYNSDR-------------------------------LCL--PYIPQLTDE------------DRLSKRRS------IGETISLQVEVESRNS-PEKEERVPAEEITYETLKKAIVDSVAVEEQE-RERRRQVVEKFQKAPFEEIAAHCGARASLLQSKLNQIFEITIRPPPSPSGTITA--AYGQPQNHSIPVYEMKFPDLCVY----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A481CVU6-1", "uniprot_id": "A0A481CVU6_PIG", "id": "A0A481CVU6-1", "name": "Protein EFR3 homolog B", "aln": "---------------MYG-----------VCGCCGALRPRYKRLVDNIFPEDPEDGLVKTNMEKLTFYALSAPEKLDRIGAYLSERLIRDVGRHRYGYVCIAMEALDQLLMACHCQS-INLFVESFLKMVAKLLES-EKPNLQILGTNSFVKFANIEEDTPSYHRSYDFFVSRFSEMCHSSHEDLEIKTKIRMSGIKGLQGVVRKT-----------VNDELQANIWDPQHMDKIVPS--LLFNLQHVEEAESRSPSPLQAPEKE-------KENPAELAERCLRELLGRAAFGNIKNAIKPVLIHLDNHSLWEPKVFAIRCFKIIMYSIQPQHSHLVIQQLLSHLDANSRSAATVRAGIVEVLSEAAVIAATGSVGPTVLEMFNTLLR-----QLRLSIDYALTGSYDGAISLG-TKIIKEHEERMFQEAVIKTIGSFASTLPTYQRSEVILFIMSKVPLPSLHHPMETGRTGENRNRLTQIMLLKSLLQVSTGFQCNNMMSALPSNFLDRLLSTVLMEDAEIRLFVLEILISFIDRHGNRHKFSTISTLSDISVLKLKVDKCSRQD----------TIFMKKHSQQLYRHIYLSCKEETNIQKHYEALYGLLALIS----IELANEEVVVDLIRLVLAVQDVAQVNEENLPVYNRCALYALGAAYLNLISQLTTVPAFCQHIHEVIETRKKEAPYMLPEDVFVERPRLS-QNLDGVVIELLFRQSKISEVLGGSGYNADR-------------------------------LCL--PYIPQLTDE------------DRLSKRKS------IGETISLQVEVESRNS-PEKEERVPAEEITYETLKKAIVDSVAVEEQE-RERRRQVVEKFQKAPFEEIAAHCGARASLLQSKLNQIFEITIRPPPSPSGTITA--AYGQPQNHSIPVYEMKFPDLCVY----------------------------------------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q6ZQ18-1", "uniprot_id": "EFR3B_MOUSE", "id": "Q6ZQ18-1", "name": "Protein EFR3 homolog B", "aln": "---------------MYG-----------VCGCCGALRPRYKRLVDNIFPEDPEDGLVKTNMEKLTFYALSAPEKLDRIGAYLSERLIRDVGRHRYGYVCIAMEALDQLLMACHCQS-INLFVESFLKMVAKLLES-EKPNLQILGTNSFVKFANIEEDTPSYHRSYDFFVSRFSEMCHSSHDDLEIKTKIRMSGIKGLQGVVRKT-----------VNDELQANIWDPQHMDKIVPS--LLFNLQHVEEAESRSPSPLQAPEKE-------KENPAELAERCLRELLGRAAFGNIKNAIKPVLIHLDNHSLWEPKVFATRCFKIIMYSIQPQHSHLVIQQLLSHLDANSRSAATVRAGIVEVLSEAAIIAATGSVGPTVLEMFNTLLR-----QLRLSIDYALTGSYDGAVSLG-SKIIKEHEECMFQEAVIKTIGSFASTLPTYQRSEVILFIMSKVPLPSVHHPVETGRTGENRNRLTQIMLLKSLLQVSTGFQCNNMMSALPSNFLDRLLSTALMEDAEIRLFVLEILISFIDRHGNRHKFSTISTLGDISVLKLKVDKCSRQD----------TVFMKKHSQQLYRHIYLSCKEETNIQKHYEALYGLLALIS----IELANEEVVVDLIRLVLAVQDVAQVNEENLPTYNRCALYALGAAYLNLISQLTTVPAFCQHIHEVIETRKKEAPYMLPEDVFVEKPRLS-QNLDGVVIEFLFRQSKISEVLGGSGYNSDR-------------------------------LCL--PYIPQLTDE------------DRLSKRKS------IGETISLQVEVESRNS-PEKEERVPAEEITYETLKKAIVDSVAVEEQE-RERQRQVVEKFQKAPFEEIAAHCGARASLLQSKLNQIFEITIRPPPSPSGTISA--AYGQPQNHSIPVYEMKFPDLCVY----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IGJ0-2", "uniprot_id": "EFR3_DROME", "id": "Q8IGJ0-2", "name": "Protein EFR3 homolog cmp44E", "aln": "MALIRCCFEPPELPEFFDSFVQKCTDPSCCCGCCSALRPRYKRLVDNIFPVNPEDGLVKSNMEKLTFYSLSSPDKLDRIGEYLYQKATKDINRKRYKLAEIAMEAMDLLLQACHAQTTLNLFVESFLRMVQKLLED-SNPNLKIMATNSFVKFANINEDTPSYHRRYDFFISKFSSMCHS--DAASMRDSLRLAGIKGLQGVIRKT-----------VSDDLVENIWEAEHMEKIVPS--LLFNMQFCVNVMFVKKNLLASGDLTPVE-DATNVTPPALAEEVLRELVGRASFGHIRSVLKPLLTHLDRHELWVPNTFAIHTFRIVMISIQPQYSYTVVETLMQHLDNNFKSSPKTRTSLAVVLSKIIAIAAGESVGPSALDIINNLLT-----HLRT------------SVSTT-SEITPE--ESQYQEALINALGEFANHHPDYQKIEIMLFIMNTVP--------DLSKKSKG-DQMLQNILLKSLLKVGTQYSTVSFEKAFPASFLQPLLKMARAPHNPTRMVVMQILQALLDRHQNEQVLSSVSVK---PYPALSQEPPSRSD----------IIFTHKYGANIMQALIDSMALSDRVDALTSSFN-TAALLI----VEMSCNETVQEFLLFILGIQQVACT-VDTLGNVHKCSLHAISIGLLVLISRVSGINNLLEYAQKIVDARREEASHFLPP--LLEPKKLAGKTFNLQLPHLAIDKLALGECLQNAGMDAQR-------------------------------LNTGAPYSLNQTDHPGHRHSWVESVSNQLTQRNS------SADLTVYNGDVDSVSSSPGVCKKLLAPEFNFDAMKRALAEPTEAAKREQRERQMQIVRTFREGEFDDLMRRTEPKHDLIQNRLNELFNSLAVERQITQSDTKS--SQLQASNE-KPIYETNFPELFYY----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q54GC3-1", "uniprot_id": "Q54GC3_DICDI", "id": "Q54GC3-1", "name": "", "aln": "--------------------------------MAFGKTKKYKRIVKTIFPQVEGGEMQLGNISKLVYFCEMSPEQLQKVGPYIEAKAQKNLSKKRLVYVSTCIIIIRELIIGCRKHL--ALFSGNATRLMKILLIQTEYPSLQIEATETFIRFASVQDDSNQIPPEIDEFIKYFIIMAKNMDNDDTMRRTIRGEGLRGVTAYVSLASLTDDLDTFITKHTDIIYTILDNMQYRDQIPSPLIIINIKIVIIDKYHNRSMENRNQHHDETGETTITNVKLLATECLKDLSGRVDNMTVASLVTTIVNYLDSHQKWNFEKFAVHALTSVTQSIKGQNYTIMLTSFLRHLELDHPPTVTKEIVLTSVAIVNDTTSSINMVVTSLLKILVRSIENSSKHLPDVDQQFSLQNSIVESIGLIGRKIKSTGKKVEIMNQIINSLRDIIKSNNSTTNNLINLITFSFVQCIS-QVASTLNDLVVGPSLVPLLDLTSKLIGIHQSPTTSHQTKTFIQSTFQSFLIQQIQFKSLFDQLMNQQIIQFNNNDGVLEFLNNCSKPIIETIISGLKSKNNQPDNIISIFKTLVALLIREKSKQIQYSIPMLLKLESEIDDNNNSNQLPIRLVRSIHLLISSYLIVVARLYRSKELEDYVEQVSNYRKSMNIHCKYLLFDIKSLSGLVIANTQKHIYSDQDQDISTLVSGSSSSSSTTIATTKITTQTTLVTSTTIEETITTQETFEKIENKEKEEEKQEEEEIEEPKEERKDIINHEKVIEILCAIQSLCAEIPNLKSILLEGADPNNLSTISNLQILQQTPPPPRIVTNEINSNTTTTATISNDGYLNEVNTTTTTTTTTITSPMKLPILNKSRESVVLSSTIPTMFQKSLTFDSFKQFVNYFDENNHAVNGVTAAANQQAQQIQNGSISGVVKVERNNVHNAIFEQTFELTCAKIVEAQHINKEYSDLMEILKLSEQQNLIENNNNNRAPIFIN", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :***:*..*** . : *:.**.::. :*::*:::* *: : :::.::* . .: : *: .*: : ** . ::: ** . . *.*:* .*::*::**.:::*: . * *:. * *.:. : :: .:* *::*: . : : :: .* : : . :** :::*:: . . : . ** . *::* **. : . :..:: :** *. * : ** : : : **: * :: :: **: : .: . . :. * :: * .: *.:: : ::. :* : : :*::: .: . . : *: :. * . . . : * ..*: : .:: . :: :* . .: : : : :.. . :.. * . . .: * :: :: . :: : . .:: .: *: : : .* : : * . :* :. * : . : . .: :.: . :. . . . : * : . : :: * * . . :: :: . : . : .. : : . ::. .: . .:* : *::. : : . : :* : .. : : .* .::* .* ", "identical_positions": 83, "similar_positions": 262, "identity": "8.46%" }, { "cls_id": "homologset.oma.815654", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1RRK5-1", "uniprot_id": "F1RRK5_PIG", "id": "F1RRK5-1", "name": "", "aln": "MESSDEESVHRRRVHLRPFTLRSPAPVTLHLLPCEVPVSRPAPVGRFFTPAIRQGPYGLEASFRGRSLRGEEVAVPPGLVGYVMTEEQ-GEVSVGKQDFSEGSEEDHEVMESPETLERDFDRFIGATASFSSFTLWGLETIPGPDSKVRGALTWPSLAAAIHA---QVPED--", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q2M2U4-1", "uniprot_id": "RNH2C_BOVIN", "id": "Q2M2U4-1", "name": "Ribonuclease H2 subunit C", "aln": "MENSYEETIDKRRVHLRPDTLRDPAPASLHLLPCEVPVNRPTPVGRFFTPAIRMGRDGLEASFRGRSLRGEEVVVPPGFVGYVVTEEK-AEVLMGKQDDHERQEQ--ELLEPPEALERDCDRFMGATASFSSFTVWGLESIPGPDAKLRGALSWPSLAAAIHA---QVPED--", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q8TDP1-1", "uniprot_id": "RNH2C_HUMAN", "id": "Q8TDP1-1", "name": "Ribonuclease H2 subunit C", "aln": "MESGDEAAIERHRVHLRSATLRDAVPATLHLLPCEVAVDGPAPVGRFFTPAIRQGPEGLEVSFRGRCLRGEEVAVPPGLVGYVMVTEE-KKVSMGKPDPLRDSGTD-DQEEEP--LERDFDRFIGATANFSRFTLWGLETIPGPDAKVRGALTWPSLAAAIHA---QVPED--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A434-1", "uniprot_id": "D4A434_RAT", "id": "D4A434-1", "name": "", "aln": "MKNPEEAGDDKQRIHLRPGSLRGAAPAKLHLLPCDVLVSRPAPVERFFTPAVRHGADGLQVSFRGRGLRGEDVAVPPGFAGFVMVTEEMGEGLIGKLNFSGDAEDKADEAQEP--LERDFDRFIGATGSFSHFTLWGLETVPGPDAKVHRALGWPSLAAAIHA---QVPED--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ18-1", "uniprot_id": "RNH2C_MOUSE", "id": "Q9CQ18-1", "name": "Ribonuclease H2 subunit C", "aln": "MKNPEEAADGKQRIHLRPGSLRGAAPAKLHLLPCDVLVSRPAPVDRFFTPAVRHDADGLQASFRGRGLRGEEVAVPPGFAGFVMVTEEKGEGLIGKLNFSGDAEDKADEAQEP--LERDFDRLIGATGSFSHFTLWGLETVPGPDAKVHRALGWPSLAAAIHA---QVPED--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A9J7JDW6-1", "uniprot_id": "A0A9J7JDW6_CRIGR", "id": "A0A9J7JDW6-1", "name": "", "aln": "MESSDEAADSKQRVHLRPDSLRAAAPATLHLLPCEVQVSRPAPVERFFTPAVRHGVDGLQVSFRGRGLRGEEVAVPPGFSGFVMVTEEMGEGLIGKLNFSGDAEDKTEETQEP--LERDFDRFMGATGSFSHFTLWGLETVPGPDAKVHKALGWPSLAAAAHRSTWKLSQNRI", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:. * ::*:***. :** ..*..******:* *. *:** ******:* . **:.***** ****:*.****: *:*:. *: : :** : : : * **** **::***..** **:****::****:*:: ** ******* * ::.:: ", "identical_positions": 81, "similar_positions": 45, "identity": "46.82%" }, { "cls_id": "homologset.oma.815669", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVK9-1", "uniprot_id": "Q5FVK9_RAT", "id": "Q5FVK9-1", "name": "", "aln": "--MSGGRRKEEPPQPQ---LANG---ALKVSVWSKVLRSDAAWDDKDEFLDVIYWFRQIIAVVLGVIWGILPLRGFLGIAGFCLINAGVLYLYFSNYLQIDEEEYGGTWELTKEGFMTSFALFMVIWIIFYTAIHYD--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQT9-1", "uniprot_id": "RCAF1_MOUSE", "id": "Q9CQT9-1", "name": "GEL complex subunit OPTI", "aln": "--MSGGRRKEEPPQPQ---LANG---ALKVSVWSKVLRSDAAWDDKDEFLDVIYWFRQIIALVLGVIWGVLPLRGFLGIAGFCLINAGVLYLYFSNYLQIDEEEYGGTWELTKEGFMTSFALFMVIWIIFYTAIHYD--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BUV8-1", "uniprot_id": "RCAF1_HUMAN", "id": "Q9BUV8-1", "name": "GEL complex subunit OPTI", "aln": "--MSGGRRKEEPPQPQ---LANG---ALKVSVWSKVLRSDAAWEDKDEFLDVIYWFRQIIAVVLGVIWGVLPLRGFLGIAGFCLINAGVLYLYFSNYLQIDEEEYGGTWELTKEGFMTSFALFMVCVADSFTTGHLDHLLHCHPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A287A7K9-1", "uniprot_id": "A0A287A7K9_PIG", "id": "A0A287A7K9-1", "name": "", "aln": "LQTPTPFRSARAPQPQ---LANG---ALKVSVWSKVLRSDAAWEDKDEFLDVIYWFRQIIAVVLGVIWGVLPLRGFLGIAGFCLINAGVLYLYFSNYLQIDEEEYGGTWELTKEGFMTSFALFMVIWIIFYTAIHYD--------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A8V0ZIV7-1", "uniprot_id": "A0A8V0ZIV7_CHICK", "id": "A0A8V0ZIV7-1", "name": "", "aln": "--MSGARRREEPPHAQQHALANGGGAGPRGSVWGKALRSDSAWHDKDEFLDVIYWFRQIIAVILGVIWGVVPLKGFVGIAIFCLINAGVLYLYFSSFQQIDEEEYGGTWELTKEGFMTSFALFLVVWIIFYTAIHYD--------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "F1RD59-1", "uniprot_id": "F1RD59_DANRE", "id": "F1RD59-1", "name": "", "aln": "--MSSSSKRKEEIHAV-----NG---GVKQSTWSKAISCKAVWEEKDEFLDVVYWFRQIIAIILGVIWGVAPLKGFLGIAIFCIINAGVLYVYFSSFQQVDEEEYGGTWELTKEGFMTSFALFLVVWIIFYTALHYD--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q54I50-1", "uniprot_id": "Q54I50_DICDI", "id": "Q54I50-1", "name": "Rab5-interacting protein", "aln": "--MSETKERSQ------------------LLLLKNSFNKDFKFTNK-EIAQNVHWLRQIVSILVGIIVGSIPVIGFPGFIAFLIFTCGFVAIYYTKVLEIEEDDFK--WELMREGFMSSLTIFVISWIIAYNSLYV---------", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : : . : :* *: : ::*:***:::::*:* * *: ** *: * ::..*.: :*::. :::*::: *** :****:*:::*:: :.: : ", "identical_positions": 26, "similar_positions": 48, "identity": "17.93%" }, { "cls_id": "homologset.oma.815681", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P0CG13-1", "uniprot_id": "CTF8_HUMAN", "id": "P0CG13-1", "name": "Chromosome transmission fidelity protein 8 homolog", "aln": "--------MVQIVISS-----------------------------------ARAGGLAEWVLMELQGEIEARYSTGLAGNLLGDLHYTTEGIPVLIVGHHILYGKIIHLEKPFAVLVKHTPGDQD------------------------------CDELGRETGTRYLVTALIKDKILFKTRPKPIITSVPKKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3HKU5-1", "uniprot_id": "G3HKU5_CRIGR", "id": "G3HKU5-1", "name": "", "aln": "--------MVQIVISS-----------------------------------TGAGGLAEWVLMELQGEIEARYSTGLAGNLLGDLHYTTEGIPVLIVGHHILYGKIIHLEKPFAVLVKHTPGEQD------------------------------CDELGQETDTRYLVTALIKNKILFKTRPKPIITNVPKKV", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "P0CG15-1", "uniprot_id": "CTF8_MOUSE", "id": "P0CG15-1", "name": "Chromosome transmission fidelity protein 8 homolog", "aln": "--------MVQIVISS-----------------------------------TGAEGLAEWVLMELQGEIEARYSTGLAGNLLGDLHYTTEGIPVLIVGHHILYGKTIHLEKPFAVLVKHTPGKQD------------------------------CDEPGRGTGTQYLVTALIKNKILFKTRPKPIITNVPKKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8V0Y4N4-1", "uniprot_id": "A0A8V0Y4N4_CHICK", "id": "A0A8V0Y4N4-1", "name": "", "aln": "GLIPSCPLAVTAALQSPHYGAGHHLQVSECLGLPCSGAPCPVGDTAPLPGSAGAGGLERWVLVELQGEVEPRGGGALPGSLLGDLHYTREGIPVLIVGHHILYGKVVQLEKPFAVLMKQAADP---------------------------------------AGTRYAVTALIKTKLLFKTRPKPIITNVPKKV", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q2PDX2-1", "uniprot_id": "Q2PDX2_DROME", "id": "Q2PDX2-1", "name": "Chromosome transmission fidelity protein 8 homolog", "aln": "---------MPIVVKT------------------------------------QNAGKGDWAIIELQGDLEVRSNQDMHGQFIGDLYYNKYGQPILIIGHHILQGREQKLDKPFAVLEKSKTNEGERLLETSMASQDVSMLNATTGAERTVLDHTIAQEHKSRQRTEYTVRAVCTKKLIFKSRPKPIIANVAKSV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:.: * *.::****::* * . : *.::***:*. * *:**:***** *: :*:****** * .. *.* * *: . *::**:******:.*.*.*", "identical_positions": 47, "similar_positions": 34, "identity": "24.23%" }, { "cls_id": "homologset.oma.815698", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9P000-1", "uniprot_id": "COMD9_HUMAN", "id": "Q9P000-1", "name": "COMM domain-containing protein 9", "aln": "---MAALTAEHFAALQSLL----------KASSKDVVRQLCQESFSSSALGLKKLLDVTCSSLSVTQEEAEELLQALHRLTRLVAFRDLSSAEAILALFPENFHQNLKNLLTKIILEHVSTWRTEAQANQISLPRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQEDPSLCGDKPSISAVTVELSKETLDTMLDGLGRIRDQLSAVASK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1MIC5-1", "uniprot_id": "F1MIC5_BOVIN", "id": "F1MIC5-1", "name": "", "aln": "---MAALTAENFAALQSLL----------KASSKDVVRQLCQESFSSSALGSKNLLDVTCSSLSVTQEEAEQLLQALHRLTRLAVFRDLSSAEAILALFPENFHQNLKNLLTKIILEHVSAWRAEAQVNQISLPRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQEDPSLCGDRPSVSAVTVELSKETLDTMLDGLGRIRDQLSAVASK", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q8K2Q0-1", "uniprot_id": "COMD9_MOUSE", "id": "Q8K2Q0-1", "name": "COMM domain-containing protein 9", "aln": "---MAALTAEHFVALQSLL----------KASSKDVVRQLCQESFSSSCLDSESLLDKTCSSLSVPQGEAAQLLQALHHFTRLVAFRDLSSAEAILALFPENFHQNLKNLLTKIIVEHISTWRAEAQANQISLPRLVDLDWRVDIKTSSDNISRMAVPTCLLQMKIQEDPSLCGEKPSISAVTMELSKETLDTMLDGLGRIRDQLSAVANK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3MIE7-1", "uniprot_id": "Q3MIE7_RAT", "id": "Q3MIE7-1", "name": "", "aln": "MLMVPGSACEAHVHCDGSLCPWDAGKDGGKASSKDVVRQLCQESFSSSALHSKTLLDNTCSSLSVTQEEAEQLLQALHHFTRLVAFRDLSSAEAILALFPENFHQNLKNLLTKIILEHISTWRTEAQANQISLPRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQEDPSLCGEKPSISAVTVELSKETLDTMLDGLGRIRDQLSAVANK", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. :.* .. :. * *******************.* :.*** *******.* ** :******::***..******************************:**:*:**:***.**********************.***********************::**:****:*************************.*", "identical_positions": 159, "similar_positions": 29, "identity": "75.36%" }, { "cls_id": "homologset.oma.815715", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2C7-1", "uniprot_id": "A0A0G2K2C7_RAT", "id": "A0A0G2K2C7-1", "name": "ubiquitinyl hydrolase 1", "aln": "----------------------------MTATTRGSPVGGNDNQGQAPDGQSQPPLQQNQTSSPDSSNENSPATPPDEQGQGDAPPQIEDEE------------PAFPHTDLAKLDDMINRPRWVVPVLPKGELEVLLEAAIDLSKKGLDVKSEACQRFFRDGLTISFTKILTDEAVSGWKFEIHRCIINNTHRLVELCVAKLAQDWFPLLELLAMALNPHCKFHIYNGTRPCESVSSS----VQLPEDELFARSP-DPRSPKGWLVDLLNKFGTLNGFQILHDRFING----------------------------SALNVQIIAALIKPFGQCYEFLTLHTVKKYFLPIIEMVPQFLENLTDEELKKEAKNEAKNDALSMIIKSLKSLASRVPGQEETVKNLEIFRLKMILRLLQISSFNGKMNALNEVNKVISSVSYYTHR-----HGSSE-EEEWLTAERMAEWIQQNNILSIVLRDSLHQPQYVEKLEKILRFVIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSPEQLDHLFDCFKASWTNASKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAHSDDVPVDIMDLALSAHIKILDYSCSQDRDTQKIQWIDRFIEELRTNDKWVIPALKQIREICSLFGEAPQNLSSSRFSQTQRSPHVFYRHDLINQLQHNHALVTLVAENLATYMESMRLYGRDNEDYDPQTVRVGSRYSHVQEVQERLNFLRFLLKDGQLWLCAPQAKQIWKCLAENAVYLCDREACFKWYSKLMGDEPDLDPDINKDFFESNVLQLDPSLLTENGMKCFERFFKAVNCREGKLVAKRRAYMMDDLELIGLDYLWRVVIQSNDDIASRAIDLLKEIYTNLGPRLQVNQVVIHEDFIQSCFDRLKASYDTLCVLD-----------GDKDSINCAR-------QEAVRMVRVLTVLREYINECDSDYHEERTILPMSRAFRGKHLSFIVRFPNQGRQVDDLEVWSHTNDTIGSVRRCILNRIKAN-VAHTKIELFVG-GELIDPGDDRKLIGQLNLKDKSLITAKLTQISSNMPSSPDSSSDSSTGSPGNHGNHYSDGPNPEVESCLPGVIMSLHPRYISFLWQVADLGSSLNMPPLRDGARVLMKLMPPDSTTIEKLRAICLD-------------HAKLGESSLSPSLDS-------------LFFGPSASQVLYLTEVVYALLMPAGAPLADDSSDFQFHFLKSGGLPLVLSMLTRNNFLPNADMETRRGAYLNALKIAKLLLTAIG--YGHVRAVAEACQPGVEGVNPMTSVNQVTHDQAVVLQSALQSIPNPSSECMLRNVS------VRLAQQISDEASRYMPDICVIRAIQKIIWTSGCGGLQLVFSPNEEVTKIYEKTNAGNEPDLEDEQVCCEALEVMTLCFALIPTALDALSKEKAWQTFIIDLLLHCHSKTVRQVAQEQFFLMCTRCCMGHRPLLFFITLLFTVLGSTARERAKHSGDYFTLLRHLLNYAYNSNINVPNAEVLLNNEIDWLKRIRDDVKRTGETGVEETILEGHLGVTKELLAFQTPEKKFHIGCEKGGANLIKELIDDFIFPASNVYLQYMRNGELPAEQAIP-VCGSPATINAGFELLVALAVGCVRNLKQIVDSLTEMYYIGTAITTCEALTEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQD-----NESNVDPRDDVFGYPQQFEDKPPLSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAMLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGVAKLEGDNVNPESQLIQQNEQSESEKAGSTKYRLVGVLVHSGQASGGHYYSYIIQRNGGDGEKNRWYKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYERMDTIDHDDEVIRYISEIAITTRPHQIVMPSAIERSVRKQNVQFMHNRMQYSLEYFQFMKKLLTCNGVYLNPPPGQDHLSPEAEEITMISIQLAARFLFTTGFHTKKIVRGSASDWYDALCILLRHSKNVRFWFAHNVLFNVSNRFSEYLLECPSAEVRGAFAKLIVFIAHFSLQDGPCPSPFASPGPSSQAYDNLSLSDHLLRAVLNLLRREVSEHGRHLQQYFNLFVMYANLGVAEKTQLLKLSVPATFMLVSLDEGPGPPIKYQYAELGKLYSVVSQLIRCCNVSSRMQSSINGNPSLPNPFGDPNLS-QPIMPIQQNVVDILFVRTSYVKKIIEDCSNSDETVKLLRFCCWENPQFSSTVLSELLWQVAYSYTYELRPYLDLLLQILLIEDSWQTHRIHNALKGIPDDRDGLFDTIQRSKNHYQKRAYQCIKCMVALFSSCPVAYQILQGNGDLKRKWTWAVEWLGDELERRPYTGNPQYTYNNWSPPVQSNETSNGYFLERSHSARMTLAKACELCPEEEPDDQDAP---------DEHESPPPE------------------------------------DAPLYPHSPGSQYQQNNHVHGQPYTGPAAHHMNNPQRTGQRAQENYEGSEEVSP-------------------------------PQTKDQ----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70398-1", "uniprot_id": "USP9X_MOUSE", "id": "P70398-1", "name": "Ubiquitin carboxyl-terminal hydrolase 9X", "aln": "----------------------------MTATTRGSPVGGNDNQGQAPDGQSQPPLQQNQTSSPDSSNENSPATPPDEQGQGDAPPQIEDEE------------PAFPHTDLAKLDDMINRPRWVVPVLPKGELEVLLEAAIDLSKKGLDVKSEACQRFFRDGLTISFTKILTDEAVSGWKFEIHRCIINNTHRLVELCVAKLAQDWFPLLELLAMALNPHCKFHIYNGTRPCESVSSS----VQLPEDELFARSP-DPRSPKGWLVDLLNKFGTLNGFQILHDRFING----------------------------SALNVQIIAALIKPFGQCYEFLTLHTVKKYFLPIIEMVPQFLENLTDEELKKEAKNEAKNDALSMIIKSLKNLASRVPGQEETVKNLEIFRLKMILRLLQISSFNGKMNALNEVNKVISSVSYYTHR-----HGSSE-DEEWLTAERMAEWIQQNNILSIVLRDSLHQPQYVEKLEKILRFVIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSPEQLDHLFDCFKASWTNASKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAHSDDVPVDIMDLALSAHIKILDYSCSQDRDTQKIQWIDRFIEELRTNDKWVIPALKQIREICSLFGEAPQNLS-----QSQRSPHVFYRHDLINQLQHNHALVTLVAENLATYMESMRMYGRDNEDYDPQTVRLGSRYSHVQEVQERLNFLRFLLKDGQLWLCAPQAKQIWKCLAENAVYLCDREACFKWYSKLMGDEPDLDPDINKDFFESNVLQLDPSLLTENGMKCFERFFKAVNCREGKLVAKRRAYMMDDLELIGLDYLWRVVIQSNDDIACRAIDLLKEIYTNLGPRLQVNQVVIHEDFIQSCFDRLKASYDTLCVLD-----------GDKDSINCAR-------QEAVRMVRVLTVLREYINECDSDYHEERTILPMSRAFRGKHLSFIVRFPNQGRQVDDLEVWSHTNDTIGSVRRCILNRIKAN-VAHTKIELFVG-GELIDPGDDRKLIGQLNLKDKSLITAKLTQISSNMPSSPDSSSDSSTGSPGNHGNHYSDGPNPEVESCLPGVIMSLHPRYISFLWQVADLGSSLNMPPLRDGARVLMKLMPPDSTTIEKLRAICLD-------------HAKLGESSLSPSLDS-------------LFFGPSASQVLYLTEVVYALLMPAGAPLTDDSSDFQFHFLKSGGLPLVLSMLTRNNFLPNADMETRRGAYLNALKIAKLLLTAIG--YGHVRAVAEACQPGVEGVNPMTSVNQVTHDQAVVLQSALQSIPNPSSECMLRNVS------VRLAQQISDEASRYMPDICVIRAIQKIIWTSGCGGLQLVFSPNEEVTKIYEKTNAGNEPDLEDEQVCCEALEVMTLCFALIPTALDALSKEKAWQTFIIDLLLHCHSKTVRQVAQEQFFLMCTRCCMGHRPLLFFITLLFTVLGSTARERAKHSGDYFTLLRHLLNYAYNSNINVPNAEVLLNNEIDWLKRIRDDVKRTGETGVEETILEGHLGVTKELLAFQTPEKKFHIGCEKGGANLIKELIDDFIFPASNVYLQYMRNGELPAEQAIP-VCGSPATINAGFELLVALAVGCVRNLKQIVDSLTEMYYIGTAITTCEALTEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQD-----NESNVDPRDDVFGYPQQFEDKPPLSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAMLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGVAKLEGDNVNPESQLIQQNEQSESEKAGSTKYRLVGVLVHSGQASGGHYYSYIIQRNGGDGEKNRWYKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYERMDTIGHDDEVIRYISEIAITTRPHQIVMPSAIERSVRKQNVQFMHNRMQYSLEYFQFMKKLLTCNGVYLNPPPGQDHLSPEAEEITMISIQLAARFLFTTGFHTKKIVRGSASDWYDALCILLRHSKNVRFWFAHNVLFNVSNRFSEYLLECPSAEVRGAFAKLIVFIAHFSLQDGPCPSPFASPGPSSQAYDNLSLSDHLLRAVLNLLRREVSEHGRHLQQYFNLFVMYANLGVAEKTQLLKLSVPATFMLVSLDEGPGPPIKYQYAELGKLYSVVSQLIRCCNVSSRMQSSINGNPSLPNPFGDPNLS-QPIMPIQQNVVDILFVRTSYVKKIIEDCSNSDETVKLLRFCCWENPQFSSTVLSELLWQVAYSYTYELRPYLDLLLQILLIEDSWQTHRIHNALKGIPDDRDGLFDTIQRSKNHYQKRAYQCIKCMVALFSSCPVAYQILQGNGDLKRKWTWAVEWLGDELERRPYTGNPQYTYNNWSPPVQSNETSNGYFLERSHSARMTLAKACELCPEEEPDDQDAP---------DEHESPPPE------------------------------------DAPLYPHSPGSQYQQNNHVHGQPYTGPAAHHMNNPQRTGQRAQENYEGGEEVSP-------------------------------PQTKGSVKCTY-----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q93008-1", "uniprot_id": "USP9X_HUMAN", "id": "Q93008-1", "name": "Ubiquitin carboxyl-terminal hydrolase 9X", "aln": "----------------------------MTATTRGSPVGGNDNQGQAPDGQSQPPLQQNQTSSPDSSNENSPATPPDEQGQGDAPPQLEDEE------------PAFPHTDLAKLDDMINRPRWVVPVLPKGELEVLLEAAIDLSKKGLDVKSEACQRFFRDGLTISFTKILTDEAVSGWKFEIHRCIINNTHRLVELCVAKLSQDWFPLLELLAMALNPHCKFHIYNGTRPCESVSSS----VQLPEDELFARSP-DPRSPKGWLVDLLNKFGTLNGFQILHDRFING----------------------------SALNVQIIAALIKPFGQCYEFLTLHTVKKYFLPIIEMVPQFLENLTDEELKKEAKNEAKNDALSMIIKSLKNLASRVPGQEETVKNLEIFRLKMILRLLQISSFNGKMNALNEVNKVISSVSYYTHR-----HGNPE-EEEWLTAERMAEWIQQNNILSIVLRDSLHQPQYVEKLEKILRFVIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSPEQLDHLFDCFKASWTNASKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAHSDDVPVDIMDLALSAHIKILDYSCSQDRDTQKIQWIDRFIEELRTNDKWVIPALKQIREICSLFGEAPQNLS-----QTQRSPHVFYRHDLINQLQHNHALVTLVAENLATYMESMRLYARDHEDYDPQTVRLGSRYSHVQEVQERLNFLRFLLKDGQLWLCAPQAKQIWKCLAENAVYLCDREACFKWYSKLMGDEPDLDPDINKDFFESNVLQLDPSLLTENGMKCFERFFKAVNCREGKLVAKRRAYMMDDLELIGLDYLWRVVIQSNDDIASRAIDLLKEIYTNLGPRLQVNQVVIHEDFIQSCFDRLKASYDTLCVLD-----------GDKDSVNCAR-------QEAVRMVRVLTVLREYINECDSDYHEERTILPMSRAFRGKHLSFVVRFPNQGRQVDDLEVWSHTNDTIGSVRRCILNRIKAN-VAHTKIELFVG-GELIDPADDRKLIGQLNLKDKSLITAKLTQISSNMPSSPDSSSDSSTGSPGNHGNHYSDGPNPEVESCLPGVIMSLHPRYISFLWQVADLGSSLNMPPLRDGARVLMKLMPPDSTTIEKLRAICLD-------------HAKLGESSLSPSLDS-------------LFFGPSASQVLYLTEVVYALLMPAGAPLADDSSDFQFHFLKSGGLPLVLSMLTRNNFLPNADMETRRGAYLNALKIAKLLLTAIG--YGHVRAVAEACQPGVEGVNPMTQINQVTHDQAVVLQSALQSIPNPSSECMLRNVS------VRLAQQISDEASRYMPDICVIRAIQKIIWASGCGSLQLVFSPNEEITKIYEKTNAGNEPDLEDEQVCCEALEVMTLCFALIPTALDALSKEKAWQTFIIDLLLHCHSKTVRQVAQEQFFLMCTRCCMGHRPLLFFITLLFTVLGSTARERAKHSGDYFTLLRHLLNYAYNSNINVPNAEVLLNNEIDWLKRIRDDVKRTGETGIEETILEGHLGVTKELLAFQTSEKKFHIGCEKGGANLIKELIDDFIFPASNVYLQYMRNGELPAEQAIP-VCGSPPTINAGFELLVALAVGCVRNLKQIVDSLTEMYYIGTAITTCEALTEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQD-----NESNVDPRDDVFGYPQQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAMLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGVAKLEGDNVNPESQLIQQSEQSESETAGSTKYRLVGVLVHSGQASGGHYYSYIIQRNGGDGERNRWYKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYERMDTIDQDDELIRYISELAITTRPHQIIMPSAIERSVRKQNVQFMHNRMQYSMEYFQFMKKLLTCNGVYLNPPPGQDHLLPEAEEITMISIQLAARFLFTTGFHTKKVVRGSASDWYDALCILLRHSKNVRFWFAHNVLFNVSNRFSEYLLECPSAEVRGAFAKLIVFIAHFSLQDGPCPSPFASPGPSSQAYDNLSLSDHLLRAVLNLLRREVSEHGRHLQQYFNLFVMYANLGVAEKTQLLKLSVPATFMLVSLDEGPGPPIKYQYAELGKLYSVVSQLIRCCNVSSRMQSSINGNPPLPNPFGDPNLS-QPIMPIQQNVADILFVRTSYVKKIIEDCSNSEETVKLLRFCCWENPQFSSTVLSELLWQVAYSYTYELRPYLDLLLQILLIEDSWQTHRIHNALKGIPDDRDGLFDTIQRSKNHYQKRAYQCIKCMVALFSNCPVAYQILQGNGDLKRKWTWAVEWLGDELERRPYTGNPQYTYNNWSPPVQSNETSNGYFLERSHSARMTLAKACELCPEEEPDDQDAP---------DEHESPPPE------------------------------------DAPLYPHSPGSQYQQNNHVHGQPYTGPAAHHMNNPQRTGQRAQENYEGSEEVSP-------------------------------PQTKDQ----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1BWJ5-1", "uniprot_id": "E1BWJ5_CHICK", "id": "E1BWJ5-1", "name": "ubiquitinyl hydrolase 1", "aln": "----------------------------MTATTRGSPVGGNDSQGQAPDGQSQPPLQQNQTSSPDSSNENSPATPPDEQGQGDAPPQLEDEE------------PAFPHTDLAKLDDMINRPRWVVPVLPKGELEVLLEAAIDLSKKGLDVKSEACQRFFRDGLTISFTKILTDEAVSGWKFEIHRCIINNTHRLVELCVAKLSQDWFPLLELLAMALNPHCKFHLYNGTRPSETVPAG----VQLAEDELYARPP-DPRSPKGWLVDLINKFGTLNGFQILHDRFMSG----------------------------SALNVQIIAALIKPFGQCYEFLTLHTVKKYFLPIIEMVPQFLENLTDDELKKEAKNEAKNDALSMIIKSLKNLASRVPGQEETVKNLEIFRLKMILRLLQISSFNGKMNALNEVNKVISSVSYYTHR-----HGNPE-EEEWLTAERMAEWIQQNNILSIVLRDSLHQPQYVEKLEKILRFVIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSPEQLDHLFDCFKASWTNASKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAHSDDVPVDIMDQALSAHIKILDYSCSQDRDTQKIQWIDRFIEELRTNDKWVIPALKQIREICSLFGEAPQNLS-----QTQRSPHVFYRHDLINQLQHNHALVTLVAENLSAYMESMRQYAKEHGEYDPQTVRPGSRYSHVQEVQERLNFLRFLLKDGQLWLCAPQAKQIWKCLAENAVYLCDREACFKWYSKLMGDEPDLDPDINKDFFENNVLQLDPSLLTENGMKCFERFFKAVNCREGKLVAKRRAYMMDDLELIGLDYLWRVVIQGNDDIANRAIDLLKEIYTNLGPRLQVNQVVIHEDFIQSCFDRLKASYDTLCVLD-----------GDKDSINCAR-------QEAIRMVRVLTVLREYINECDSDYHEERTILPMSRAFRGKHITLVVRFPNQGRQVEDLDIWSHTNDTIGQVRRCILNRIKAN-SAHTKVELFIG-GELVDPADDRKLIGQLNLKDKTLITAKLTQINSNMPSSPDSSSDSSTGSPGNHGNHYSDGPNPEVESCLPGVIMSLHPRYISFLWQVADLGSSLNMPPLRDGARVLMKLMPPDNTTVEKLRAICLD-------------HAKLGESSLSPSLDS-------------LFFGPSASQVLYLTEVVYALLMPASAPLGEDASDFQYNFLKSGGLPLVLSMLTRNNFLPNADMETRRGAYLNALKIAKLLLTAIG--YGHVRAVAEACQPVVEGTSTVSPINQATHDQAVVLQNALQNIPNPTSECMLRNVA------IRLAQQISDEASKYIPDICVIRAVQKIVWASGCGSVQLVFSSNEEISKIYEKTNAGNEPDMEDEQVCCEALEVMTLCFALIPTALDALSKEKAWQTFIIDLLLHCHSKIVRQMAQEQFFLMATRCCMGQRPLLFFITLLFTVLGSTARERAKHSGDYFTLLRHLLNYAYNSNINVPNAEVLLNNEIDWLKRIRDEVKRTGETGVEETILEGHLGVTKELLAFQTPEKKYHIGCEKGGANLIKELIDDFIFPASNVYLQYMRNGELPAEQAIP-VCSSPATINAGFELLVALAVGCVRNLKQIVDTLTEMYYIGTAITTCEALTEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPAIRNGILAIEGTGSDVDDDMSGDEKQD-----NESNVDPRDDVFGYPHQYEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAMLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGVAKLEGDDVNPENQIIQ-NEQSENEHSGSTKYRLVGVLVHSGQASGGHYYSYIIQRNGGDGEKNRWYKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYERMDTIDKDSELTKYISELAITTKPHQIKMPSAIERSVRKQNVQFMHNRMQYSLEYFQFIKKLLTCNSVYLNPPPGQDHLLPEAEEITMISIQLAARFLFTTGFHTKKIVRGPASDWYDALCILLRHSKNVRFWFAHNVLFNVSNRFSEYLLECPSAEVRGAFAKLIVFIAHFSLQDGPCPSPFASPGPSSQAYDNLSLSDHLLRAVLNLLRREVSEHGRHLQQYFNLFVMYANLGVAEKTQLLKLNVPATFMLVALDEGPGPPIKYQYAELGKLYTVVSQLIRCCNVSSRMQSSINGNPPLANPYGDPNLS-QPIMALQQNVADILFVRTSYVKKIIEDCSNSEETIKLLRFCCWENPQFSSTVLSELLWQVAYSYTYELRPYLDLLLQILLIEDSWQTHRIHNALKGIPDDRDGLFDTIQRSKNHYQKRAYQCIKCMVALFSNCPVAYQILQSNGDLKRKWTWAVEWLGDELERRPYTGNPQYTYNNWSPPIQSNETSNGYFLERSHSARMTLAKACELCPEEEPDDPDAP---------DEHESSPPE------------------------------------DAPLYPHSPGSQYQQNNHVHGQPYTGPAAHHMNNPQRTGQRAQENYEGSEEVSP-------------------------------PQTKD-----------------------------------------------------------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "P55824-1", "uniprot_id": "FAF_DROME", "id": "P55824-1", "name": "Ubiquitinyl hydrolase FAF", "aln": "MTFDTRRHTTGQPGSTAPSSSSSTTSTTTTTTSPAQSAGSGSGIGTGTGTVANSSLPGGGSGSLDGNQDQQPATDSQSSDDVAASLSANSVDSTITIVPPEKLISSFPTTKLRSLTQKISNPRWVVPVLPEQELEVLLNAAIELTQAGVDHDCEPCVEFYRNGLSTSFAKILTDEAVNSWKNNIHHCILVSCGKLLHLIAIHMQRDNPYLLDLLAIVFDPENKFNTFNAGRQPECFAAPDYIWGQLDSNKMYARPPPEPKNARGWLVDLINRFGQLGGFDNLLERFNIGLELLKRNQNKCTGKNISVEGRVENGAQDNRLTLALIHSLLRPFGQCYELLMPATIAKYFMPTWNVVLDLLDSFTDEELKREVKPEGRNDYINGIVKSARLLASRLTGQEELIRDLEMFRLKMILRLLQVSSFNGKMNALNEINKVLSSVAYFSHRSQPLPHCMPEDEMDWLTADRMAQWIKSSDVLGVVLKDSLHQPQYVEKLEKIIRFLIKEQALTLDDLDAVWRAQAGKHEAIVKNVHDLLAKLAWDFTPEQLDHLFEAFQASMTTANKRQRERLLELIRRLAEDDKNGVMAQKVLKLFWTLAHSQEVPPEVLDQALGAHVKILDYSCSQERDAQKTIWLDKCVDELKSGDGWVLPALRLIRDICCLYDTTTN--------HAQRTQTSTNRQQVIERLQNDYSLVILVTNSLTAYMEKVRQMVTDSPGLDATRILIDGRFPHHVQIAERLEFLKFLLKDGQLWLCADQAKQIWHCLAVNAVFPADREECFRWFGKLMGEEPDLDPGINKDFFENNILQLDPHLLTESGIKCFERFFKAVNSKEDKLKAIHRGYMLDNEDLIGKDYLWRVITTGGEEIASKAIDLLKEVSTALGPRLQENIAEFHEMFIGECCSRLRTHYGNIVILGKTQLQEELDAPDQSDNTNDESKDSKMRFIEAEKMCRILKVLQEYVKECDRSFSGDRVHLPLSRVTRGKNTILYIRFQNPGRSIDDMEIVTHSNETMAAFKRNLLKRIKGTSTANIKVDLFYANDEMIGVSDEINPLYQYTIRDKMNLTAKLTPVGTGLASSPDSSSDSSTGSPPRP---CPDMQRVESESTLPGVIISQNYQYTEFFLKLYQLGSDLEHGRLRDSAKVLLHLLPCDRQTIRQLKIMCKVPKAAVTVAVTGDKIAKDEEEKLYPTEQAGIEDEEEHCTPEQMFLHPTPAQVLYNLSVLHGLLIPALDPLGESALLVQSAWMHSGCAHFVLELLTKNNFLPSADMHTKRASFQCVLRLAKLFLYIVGSVLSRVGDEPMICDLDNGSRSQVDILKQNFSTMPSSSQGTLRAISAKLAVILAREMLSASPEGDRCRTLFSSTLQWSCPDISTIKAVVQLAWASSCGNLQALGNSSG------DFEDEVIVPDGQDFSMCKEALEVLTISFILNPSANEALTSDPNWPKFITSIVLKNPLRHVRQVASEQLFLASTYCAGDRRPFVYMVNLLVGALKTLVPQYESTCAEFFSVLCRTLSYGCIYNWPLQISEGLLGDEIKWLQRIRENVHATGDTQVHEELLEGHLCLAKELMFFLGADSKAQLN------ELIHELIDDFLFTASREFLHLRRHGSLRQDTVPPPVCRSPHTIAAACDLLIALCQLCVPNMKLLTNTLIDFVCT-----DTDPLREWDYLPPVGARPTKGFCGLKNAGATCYMNSVLQQLYMVPAVRVGILRAHGAATTDGEDFSGDSDLTGGGLGSALFSGPASALVSLPSSS-STIEDGLHDVRKNYHVVILKHVQAIFAHLGHSALQYYVPRGLWTHFKLLGEPVNLREQQDAVEFFMSLLESLDEGLKALGQPQLMNATLGGSFSDQKICQECPHRYSKEEPFSVFSVDIRNHSSLTESLEQYVKGELLEGADAYHCDKCDKKVVTVKRVCVKKLPPVLAIQLKRFEYDYERVCAIKFNDYFEFPRILDMEPYTVSGLAKLEG-------EVVEVGDNCQTN-VETTKYELTGIVVHSGQASGGHYFSYILSKNPANG-KCQWYKFDDGEVTECKMHEDEEMKAECFGGEYMGETYDNNLKRMQYRRQKRWWNAYMLFYTRCDQTPVQYEPSVEQLSLAES-RNMVLPLPKPIERSVRHQNIRFLHSRSIFSVEFFNFIKKLVSCN----LLSARSNKITPAAEELSLLGVQLASQFLFHTGFRTKKSLRGPVMEWYDALSHHIRSSALVRKWFANHALLSPPSRLGEYILMAPSPDVRTVFVKLVVFFCHFAINDEPLTG-----------YDGANLCEQVLISVLRLLKSEAADYGKHLPHYFSLFSMYVGLGTREKQQLLRLNVPLQFIQVALDDGPGPAIKYQYPEFSKLHQVVSHLIRCSDVSEKCQSSNQNARPLSNPFKDPNVAHEELTPLSTECMDLLFNRTGYIKKVIEDTNVGDEGLKLLQYCSWENPHFSRAVLTELLWQCGFAYCHDMRHHTDLLLNILLIDDSWQHHRIHNALNGVAEEREGLLETIQRAKTHYQKRAYQIIKCLTQLFHKSPIALQMLHTNSNITRHWSIAVEWLQGELDRQRGIG-CQYNSYSWSPPAQSNDNTNGYMLERSQSAKNTWSMAFELCPDEVSEKTDENNEPNLETNMDENKSEPVAQPGGVLEGSTGGTEQLPENKTPTTSSPSTAAWPARGDSNAIPRLSRQLFGAYTSTGSGSTSGGSAPTSALTTTAGSGANSETESSAQETTGETTINGLTNSLDQMEITAKKKCRRVIIKKLVESKDEEDATTATTAATTEVTTSPATAIATAATLEPAGMSELTTMVEKNLIISQENPQAKSSLQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*: ....*.... * ... ::..* . :.* *..:::.*** .:...: *. . :. : .:** *.* .* : *..*********: ******:***:*:: *:* ..*.* .*:*:**: **:********..** :**:**: . :*:.* . :: :* **:***:.::*. **: :*. * * ..: ** .::::**.* :*:..:******:*:** *.**: * :** * . *.: :* :*::*******:* *: ***:* ::* ::*:.:**:***:*.* *.:** :. *:** : ****:.**** :::**:***********:************:***:***:*::** * .* : :****:***:**:..::*.:**:***************:**:***:****:*** :* ************************:********:.*:** *.*.*:***:*************:****:***:*:*.****::** :::* **.**:*********:**:** *:*: ::**::.* **:***: **:**.*:. :.: ::**: *:::*::**::::** **::.*::***.:* : *. : ..*:.* :: ***:**:************ ******:*** ***: .*** **:*:.****:******.*******.*:***** ****.*:***********.:*.** * :*.**:*: :*** ******: ..::** :*******: * ****** * . :** ** .* .**:: *..: :*. .:.*. * ** :* *:*.**:**::*** .: :*. **:**. ***: : :** * **.::*::: :*:*:*:. .:* :*:***.. *: *::** . .*::. .*: : : * .::** :***** :.:.:.************** . .* . * ** *****:* : :* .*: :: :***.*: ***.*:**::*:* * *:.:*: :* ** *..* *: :: :*: *:.:**** .*::.**:** ** :.: .* :::** :**.:**:*****.***.*:*.:: .*::***:* :* .:* . *: . . : ::* . *.:*: *. : : *:: * :*. . ***..*:*: :: *:*.**.:* : ... : : ** :* .:* *****:*:.* * *:* :**:.: * .** .::*: : ***:*.**:** .* *. .:**:::::.**. .* : . : . ..::*::* : *.*. * : :* **.:**.**:***::*: **:* :.* :***** ::***: * .:.* ::. :**:******:*.**. :*: *:*.* : . * ** ** ** *. :**:**. ** *:* :.::* :: :.* **:******.**.*** **************:*****:*::* *** .*:.: .:*:***.. . .* . :.. * . .. . : **:*:: :*:*:*.**.**. * ********:*.:*:* *********:**:*** **::****.*****:* ::. .*****:****** *****. **.*:.:.******..* :********:*****:****:**:*** ****: :**************:**:** ************* ********:*:***** :::: .::.:.: :***.*.*::***********:***:.:* .:* : :*******:******.:***** :*********.:*: :***.***********:*** * * : * .:* : : : :*..******:**::*:*.* :*:*:*:*:***::** .. .::: * ***::::.:***::*** ***:*** :**.. :*****. :* * ** ***::.*:. ..*:.**:* .**.:** .*.**:**:.**:::* * .. **. .*.:::* :**.**: *.:::*:** :**.** **..**. ** ***:*.** *: *:**:****.*****.*:.**: ***:****.:**.: *** :. .*.**: ***:: : : .:. : *:** **.*:**:*** . .:* :***::*.****:** :**:***** .::* :::* : ****:****:**** *******:*:.::*:**::****:*.******** ***:. ** ..*:* *:*: *.::.*:*: ***** .**:*: * **. .**** ***:.:***:****:**: * : * ****:* .:. * **::* * *: *: . . : . . . . :* :* . :*. *:.: *.. : :. ::*. ", "identical_positions": 1214, "similar_positions": 812, "identity": "42.85%" }, { "cls_id": "homologset.oma.815716", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UPU5-1", "uniprot_id": "UBP24_HUMAN", "id": "Q9UPU5-1", "name": "Ubiquitin carboxyl-terminal hydrolase 24", "aln": "-MESEEEQHMTTLLCMGFSDPATIRKALRLAKNDINEAVALLTNERPGLDYGGYEPMDSGGGPSPGPGGGPRGDGGGDGGGGGPSRGGSTGGGGGFDPPPAYHEVVDAEK-NDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLLASTYLARLGLSESDENCRRFMDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLIELVAERIKQDPIPTGLLGVLTMAFNPDNEYHFKNRMKVSQRNWAEVFGEGNMFAVSPVSTFQKEPHGWVVDLVNKFGELGGFAAIQAKLHSEDIELGAVSALIQPLGVCAEYLNSSVVQPMLDPVILTTIQDVRSVEEKDLKDKRLVSIPELLSAVKLLCMRFQPDLVTIVDDLRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTLSKSVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWKIQSGQSSTVIENIHTIIAAAAVKFNSDQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARFETTSGKVLDVLWELAHLPTLPSSLIQQALEEHLTILSDAYAVKEAIKRSYIIKCIEDIKRPGEWSGLE----------------KNKKDGFKSSQLNNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLIACHRLAAAVAGPGGLSGSTLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFNLFKTFFENVNLCDHRLKRQGAQLYVEKLELIGMDFIWKIAMESPDEEIANEAIQLIINYSYINLNPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDFYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTVEAHSNETIGSVRWKIAKQLCSPVDNIQIFTNDSLLTVNKDQKLLHQLGFSDEQILTVKTSGSGTPSGSSADSSTSSSSSSSGVFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDS-----LGRKKTLLSESS-SQSSKSPSLSSKQQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDDMARSCAKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTMPTLLDEDLTKDGIEALSSRPFRNVSRQTSRQMSLCGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEVSDFTSTVACFMRLSWAAAAGRLDLVGSSQPIKES-NSLCPAGIRNRLSSSGSNCSSGSEGEPVALHAGICVRQQSVSTKDSLIAGEALSLLVTCLQLRSQQLASFYNLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSAHPDVQKPNQFLLGVILTAQLPLWSPTSIMRGVNQRLLSQCMEYFDLRCQLLDDLTTSEMEQLRISPATMLEDEITWLDNFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEMLGSSLIKPLLDDFLFRASRIILNSHSPAGSAAISQQDFHPKCSTANSRLAAYEVLVMLADSSPSNLQIIIKELLSMHHQPDPALTKEFDYLPPVDSRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGRDQIFKNTFQGIYSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGENGRSVDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEYRPKVYDQTNPYTDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNNDRLSILTKLVKKGEKKGLFVEKMPARIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKLKHPYYPCMAKVSLQLAIQFLFQTYLRTKKKLRVDTEEWIATIEALLSKSFDACQWLVEYFISSEGRELIKIFLLECNVREVRVAVATILEKTLDSALFYQDKLKSLHQLLEVLLALLDKDVPENCKNCAQYFFLFNTFVQKQGIRAGDLLLRHSALRHMISFLLGASRQNNQIRRWSSAQAREFGNLHNTVALLVLHSDVSSQRNVAPGIFKQRPPISIAPSSPLLPLHEEVEALLFMSEGKPYLLEVMFALRELTGSLLALIEMVVYCCFCNEHFSFTMLHFIKNQLETAPPHELKNTFQLLHEILVIEDPIQVERVKFVFETENGLLALMHHSNHVDSSRCYQCVKFLVTLAQKCPAAKEYFKENSHHWSWAVQWLQKKMSEHYWTPQSNVSNETSTGKTFQRTISAQDTLAYATALLNEKEQSGSSNGSESSPANENGDRHLQQGSESPMMIGELRSDLDDVDP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1BND0-1", "uniprot_id": "E1BND0_BOVIN", "id": "E1BND0-1", "name": "Ubiquitin carboxyl-terminal hydrolase 24", "aln": "-MESEEEQHMTTLLCMGFSDPATIRKALRLAKNDINEAVALLTNERPGLDYGGYEPMDSGGGPSPGPGGGSRGDGG---GCDGPSRGGSTGGGGGFDPPPAYHEVVDAEK-NDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLLASTYLARLGLSESDENCKRFMDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLIELVAERIKQDPIPTGLLAVLTMAFNPDNEYHFKNRMKVSQRNWAEVFGEGNMFAVSPVSTFQKEPHGWVVDLVNKFGELGGFAAIQAKLHSEDIELGAVSALVQPLGVCAEYLNSSVVQPMLDPVILNTIQDVRSVEEKDLKDKRLVSIPELLSAIKLLCMRFQPDLVTVVDDLRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTLSKSVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWKIQSGQSSTVIENIHTIIAAAAVKFNSDQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARFETTSGKVLDVLWELAHLPTLPSSLIQQALEEHLTILSDAYAVKEAIKRSYIIKCIEDIKRPGEWSGLD----------------KNKKDGFKSSQINNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLIACHRLAAAVAGPGGLTGSTLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFNLFKTFFENVNLCDHRLKRQGAQLYVEKLELIGMDFIWKIAMESPDEEIANEAIQLIINYSYINLNPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDFYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTVEAHSNETIGSVRWKIAKQLCSPVDSIQIFTNDSLLTVNKDQKLLHQLGFSDEQILTVKTSGSGTPSGSSADSSTSSSSSSSGVFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDS-----LGRKKTLLSETS-SQSSKSPSLSSKQQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDDMARNCAKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTLPTLLDEDLTKDGIEALSSRPFRNVSRQTSRQMSLCGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEVGDFTSTVACFMRLSWAAAAGRLDLVGSSQPIKES-NSLFPAGIRNRLSSSGSNCSSGSEGDPVALHAGICVRQQSVSTKDSLIAGEALSLLVTCLQLRSQQLASFYNLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSAHPDVQKPNQFLLGVILTAQLPLWSPTSIMRGVNQRLLSQCMEYFDLRCQLLDDLTTSEMEQLRISPATMLEDEITWLENFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEMLGSSLIKPLLDDFLFRASRIILNSHSPAGSAAISQQDFHPKCSTVNSRLAAYEVLVMLADSSPSNLQIITKELLSMHHQPDPALTKEFDYLPPVDSRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGRDQIFKNTFQGIYSDQKICKDCPHRYEREETFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRTTVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGENGRSTDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEYRPKVYDQTNPYTDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNNDRLSILTKLVKKGEKKGLFVEKMPVRIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKLKHPYYPCMAKVSLQLAIQFLFQTYLRTKKKLRVDTEEWIATIEALLSKSFDACQWLVEYFISSEGRELIKIFLLECNVREVRVAVATILEKTLDSALFYQDKLKSLHQLLEVLLALLDKDVPENCKNCAQYFFLFNTFVQKQGIKAGDLLLKHSALRHMISFLLGASRQSTQIRRWSSAQAREFGNLHNTVALLVLHSDVSSQRNVAPGVFKQRPPISIAPSSPLLPLHEEVEALLFLSEGKPYLLEVMFALRELTGSLLALIEMVVYCCFCNEHFSFTMLHFIKNQLETAPPHELKNTFQLLHEILVIEDPIQVERVKFVFETENGLLALMHHSNHVDSSRCYQCVKFLVTLAQKCPAAKEYFKENSHHWSWAVQWLQKKMSEHYWTPQSNVSNETSTGKTFQRTISAQDTLAYATALLNEKEQSGSSNGSESSPANENGERHLQQGSESPMMIGELRSDLDDVDP", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1LSM0-1", "uniprot_id": "F1LSM0_RAT", "id": "F1LSM0-1", "name": "Ubiquitin carboxyl-terminal hydrolase 24", "aln": "-MESEEEQHMTTLLCMGFSDPATIRKALRLAKNDINEAVALLTNERPGLDYGGYEPMDSGG-PSPGLGGGPRGDGGG--EGSGPSRGGSTGGGGGFDPPPAYHEVVDAEK-NDENGNCSGEGVEFPTTNLYELESRVLTDHWSIPYKREESLGKCLLASTYLARLGLSESDENCKRFMERCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLIELVAERMKQDPIPIGLLGVLTMAFNPDNEYHFKNRMKVSQRNWAEVFGEGNMFAVSPVSTFQKEPHGWVVDLVNKFGELGGFAAIQAKLHSEDIELGAVSALVQPLGVCAEYLNSSVVQPMLDPVILTTIQDVRSVEEKDLKDKRLVSIPELLSAIKLLCMRFQPDLVTIVDDLRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTLSKSVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWKIQSGQSSTVIENIHTIIAAAAVKFNADQLNHLFVLIQKSWETETDRVRQKLLSLIGRIGREARFEATSGKVLDVLWELAHLPTLPSSLIQQALEEHLTILSDAYAVKEAVKRSYIIKCIEDIKRPGEWSGLE----------------KNKKDGFKSSQHNNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLLACHRLAAAVAGPGGLTGLTLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFNLFKTFFENVNLCDHRLKRQGAQLYVEKLELVGMDFIWKIAMESPDEEIANEAIQLIINYSYINLNPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDFYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTVEAHSNETIGSVRWKIAKQLCSPVDNIQIFTNDSLLTVNKDQKLLHQLGFSDEQVLTVKTSGSGTPSGSSADSSTSSSSSSSGVFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDS-----LGRKKTLLSETS-SPSSKSPSLSSKQQQQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDDMARSCAKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTMPTSLDEDLTKDGIEALSSRPFRNVSRQTSRQMSLCGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEANDFTATVACFMRLSWAAAAGRLDLVGSSQPIKES-NSLFPAGIRNRLSSSGSNCSSSSEGEPAALHAGICVRQQSVSTKDALIAGEALSLLVTCLQLRSQQLASFYSLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSAHPEVQKPNQFLLGVILTAQLPLWSPTSIMRGVNQRLLSQCMEYFDLRCQLLDDLTTSEMEQLRVSPAAMLEDEVTWLDNFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEVLGSSLIKPLLDDFLFRASRIILNSHSPAGSAAISQQDFHPKCSTVNSRLAAYEVLVMLADSSPSNLQIITKELLSMHHQPDPALTKEFDYLPPVDSRSISGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGREQIFKNTFQGIYSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVAGMARQDSSSEVGENGRNMDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEYRPKVYDQTNPYPDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNNDRLSILTKLVKKGEKKGLFVEKMPARIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKLKHPHYPCMAKVSLQLAVQFLFQTYLRTKKKLRVDTEEWIATIEALLSKSLDACQWLVEYFISSEGRELVKVFLLECSVREVRVAVATILEKTLDSALFYQDKLKSLHQLLEVLLALLDKDVPENCKNCAQYFSLFNTFVQKQGIRAGDLLLRHSALRHMISFLLGVSQQNSQIRRWSSAQAREFGNLHNTVALLVLHTDVSSQRNVAPGIFKQRPPISVAPSSPLLPLHEEVEALLFLSEGKPYLLEVMFALRELTGSLLALMEMVVYCCFCNEHFSFTMLHFIKNQLETAPPHELKNTFQLLHEILVMEDPIQVERVKFVFETENGLLALMHHSNHVDSSRCYQCVKFLVTLAQKCPAAKEYFKENSHHWSWAVQWLQKKMSEHYWTPQSNVSNETSTGKTFQRTISAQDTLAYATALLNEKEQSGSSNGSESSPANENGERRLQQGSESPMMIGELRSDLDDVDP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AY13-1", "uniprot_id": "UBP24_MOUSE", "id": "B1AY13-1", "name": "Ubiquitin carboxyl-terminal hydrolase 24", "aln": "-MESEEEQHMTTLLCMGFSDPATIRKALRLAKNDINEAVALLTNERPGLDYGGYEPMDSGG-PSPGPGGGPRGDSGS--DGSGPSRGGSTGGGGGFDPPPAYHEVVDAEK-NDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLLASTYLARLGLSESDENCKRFMERCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLIELVAERMKQDPIPIGLLGVLTMAFNPDNEYHFKNRMKVSQRNWAEVFGEGNMFAISPVSTFQKEPHGWVVDLVNKFGELGGFAAIQAKLHSEDIELGAVSALVQPLGVCAEYLNSSVVQPMLDPVILTTIQDVRSVEEKDLKDKRLVSIPELLSAIKLLCMRFQPALVTTVDALRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTLSKSVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWKIQSGQSSTVIENIHTIIAAAAVKFNADQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARFEATSGKVLDVLWELAHLPTLPSSLIQQALEEHLTILSDAYAVKEAVKRSYIIKCIEDIKRPGEWSSLE----------------KNKKDGFKSSQLNNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLLACHRLAAAVAGPGGLTGLTLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFNLFKTFFENVNLCDHRLKRQGAQLYVEKLELVGMDFIWKIAMESPDEEIANEAIQLIINYSYINLNPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDFYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTVEAHSNETIGSVRWKIAKQLCSPVDNIQIFTNDSLLTVNKDQKLLHQLGFSDEQVLTVKTSGSGTPSGSSADSSTSSSSSSSGAFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDS-----LGRKKTLLSETS-SQSSKSPSLSSKQQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDDMARSCAKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTMPTSLDEDLTKDGIEALSSRPFRNVSRQTSRQMSLCGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEASDFTATVACFMRLSWAAAAGRLDLVGSSQPIKES-NSLFPAGIRSRLSSSGSNCSSSSEGEPAALHAGICVRQQSVSTKDALIAGEALSLLVTCLQLRSQQLASFYSLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSAHPEVQKPNQFLLGVILTAQLPLWSPTSIMRGVNQRLLSQCMEYFDLRCQLLDDLTTSEMDQLRISPATMLEDEITWLDNFEPNRTADCETSEADNILLAGHLRLIKTLLSLCGAEKEMLGSSLIKPLLDDFLFRASRIIVNSHSPASSAAISQQDFHPKCSTVNSRLAAYEVLVMLADSSPSNLQIITKELLSMHHQPDPALTKEFDYLPPVDSRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGREQIFKNTFQGIYSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVAGMARQDSSSEVGENGRNMDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEYRPKVYDQTNPYTDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNNDRLSILTKLVKKGEKKGLFVEKMPARIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKLKHPYYPCMAKVSLQLAIQFLFQTYLRTKKKLRVDTEEWIATIEALLSKSLDACQWLVEYFISSEGRELVKVFLLECSVREVRVAVATILEKTLDSALFYQDKLKSLHQLLEVLLALLDKDVPENCKNCAQYFSLFNTFVQKQGIRAGDLLLRHSALRHMISFLLGVSRQNSQIRRWSSAQAREFGNLHNTVALLVLHSDVSSQRNVAPGIFKQRPPISVAPSSPLLPLHEEVEALLFLSEGKPYLLEVMFALRELTGSLLALMEMVVYCCFCNEHFSFTMLHFIKNQLETAPPHELKNTFQLLHEVLVIEDPIQVERVKFVFETENGLLALMHHSNHVDSSRCYQCVKFLVTLAQKCPAAKEYFKENSHHWSWAVQWLQKKMSEHYWTPQSNVSNETSTGKTFQRTISAQDTLAYATALLNEKEQSGSSNGSESSPANENGERHLQQGSESPMMIGELRSDLDDVDP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8V0ZQ83-1", "uniprot_id": "A0A8V0ZQ83_CHICK", "id": "A0A8V0ZQ83-1", "name": "Ubiquitin carboxyl-terminal hydrolase 24", "aln": "-MESEEEQHMTTLLCMGFSDAAAIRKALRLAKNDINEAVALLTNERPGLHYGGYEPMESGQGPPPGHGSPAGGQGSR------DGDGGGGGGSGGFDPPPAYHEVVETEK-NDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLIASTYLARLGLSDSDENCKRFMDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLVDLVAERVKQDPIPVGLLGVLTMAFNPDNEYHFKNRMKVCQRNWAEVFGEGNMHAVSPISTFQKEPHGWLVDLVNRFAELGGFSAIQSKLNSEDIELGAISALVQPFGVCAEYLNSSVVQPMLDPVIHKMIKYVQNVEEKDLKDKRLVSIPELLSGIKLLCMRFQPDLVTAVDDLRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTVSKSVKNAIDTDRLLNWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWRIQSGQSSTVIENIHTIIAAAAVKFSSDQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARVETTTGKVLEVLWELAHLPTLPCSLIQQALEEHLTILSDAYAVKEAIKRSYIIKCIEDIKRKMKPPRKA----------------MSSSN-NESSQHNNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLISCHRLAASVAGPGGLVGATLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFSLFKTFFENVNLCDHRLKRQGTQLSVEKLELIGMDFIWKIAMESPDEEIANEAIQLIINYSYINLTPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDLYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTIEAHSNETVGSIRWKIAKMLNSPVDNIQIFANDSLLTVNKDQKLLHQLGFSDEQVLTVKTSGSGTPSGSSADSSTSSSNSSS-VFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDS-----LGRKKTLLSESS-SQSSKSPSLSSKHQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDEMARNCAKSFCENFLRAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTMPTLLDEDFIKDGVEALSSRPFRNVSRQASRQMSICGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEVNDFTSTVACFMRLSWAAAAGRLDLVGSSQPIKEN-NTLFPAGIRNRLSSSGSNCSSGSEGEPTALHAGICVRQQSVSTKDALIAGEALSLLVTCLQLRSQQLGSFYNLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSTHPDVQKPNQFLLSVILGAQLPLWSPTSIMRGINQRLLSQCTEYFDLRCQLLDDLTSSEMEQLKISPAAMLEDEITWLENFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEMVGSSLIKPLLDDFLFRASRIILNSHSPSGSAAISQQDFHPKCSTADSRLAAYEVLVMLADSSPSNLQLITKELLSMHHQCDPALTKEFDYLPPVDSRSISGFVGLKNGGATCYMNAVFQQLYMQPGLPEALLSIDDDTDNPDDNVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKIGRDQIFKNTFQGIFSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRTTVKRTCIKVLPNLLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGDNGRNVDQGGGGSPRKKVAPTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVVEEFELTDETLEYECFGGEYRPKVYDQSNPYPDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNSDRLSILTKLVRKGEKKGLFVEKMPVRIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKVKHPYYPCMAKVSLQLAVQFLFQTYLRTKKKLRADTEEWIATIDALLSKSIDACQWLVEYFVGPEGRELVKTFLLECSVREVRVAVATILEKTLDSALFYQEKLKSLHQLLEVLLALLDKDVPENCKNCAQYFLLFNNFVQKQGIRASSLLLRHSALRHMINFLLGPNRQSNQNRRWSSAQAREFGYLHNTVALLVLHSDVSSQRNVAPGLFKQRPPLSITTSGPLLTLHEEVEALLFLSEGKPYLIEVMYALRELTGSLSVLIEMVVYCCFCNEHFSFTVLHFIKTQLETAPPHELKNIFQLLHEILVIEDPLQVERIKFAFETENGLIALMHHSNHVDSSRCYQCVKFLVTLAQKCPTAKDYFKENSHHWSWAVQWLQKKMSEHYWAPQSNVSNETSTAKTFQRTISAQDTLAYATALLNEKDQSGSSNGSESSPANENGDRHLQQGSESPMMIGETKNDLDDVDP", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "F1Q6K1-1", "uniprot_id": "F1Q6K1_DANRE", "id": "F1Q6K1-1", "name": "Ubiquitin carboxyl-terminal hydrolase 24", "aln": "MMETEEEQHMTTLLCMGFPDPVAIRKALRLAKNDINEAVALLTNESPGLGYG-YEPMESGPSPGSGDG-----------------ENSGRTVTGGFDPPPAYHDVVESERSNDENGNCSGNSMEFPTTNLYELESRVFTDHWSIPYKREESLGKCLIASTCLARHGLADADENCKRFIDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLVDLVAERVKQDPIPIGLMGVLTMAFNPDNEYHFKNRMKACQRNWAEVFGEDSMFAVSPSSSYQKEPHGWLVDLVNRFGEMGGFTAIQCKLNQEEIEIGCVSALVQPLGVCAEYLNSSLVQPMLDPVIHKMITYVQNLEEKDLKDKRLVSIPELLSAIKLLCMRFQRELVNVVDDLRLDILLRMLKTPHFSAKMNSLKEVTKLIEESTVSKTVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELSKIWKIQAGQSSTVIENIHTIIAAAAVKFNFDQLSHLFVLIQKSWEVESDRVRQKLLSLIGRIGREARSEATTGKVLEVLWELAHLPTLPTSLVQQALEEHLTILSDAYAVKETIKRNYIIKCIEDIKKMQIQEDSKSPSETQVSFLTGTWGKKKPSSLAKSSQQTNPQTVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLITGSLVSCHRLAVSVAGSNGLSGSTLVDGRYSYQEYLEGHLKFLAFFLQEASLYLVWNRAKEIWECLVSGMDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLEPYEITMNGFNLFKTFFENVNLSDHRLKRQGTQLCVERLDLAGMDFIWRIAMESPDEDIANEAIQLIITYSYINLNPKMKKDSVSLHKKFIADCYKRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPSRSSKLVIIERLLLLAERYVITIEDLYSVPRTILPHGASFHGHPVTLHITYESTKDTFTLEAHSNETIGSIRWKIADQLSCPVDNVQIFANDSMLTMNRDQKLLNQLGFSDEQSLTVKSSGTGTPSGSSADSSASASSSSSGVFNSAYALEQEKSLPGVVMALVCNVFEMLYQLANLEEPRITLRVRKLLLLIPTDPEVQDALDNFVPKESSVWSHQKTLFTLGSGSQASKSPSLSSKQQHQQSAASILESLFRSSAPGMSTFRVLYNLEVLSSKLMPTSDDEMAKTSVKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQAMPSILDEELSKD--DTLSSRPFRNAGRQSGRQLSVCGTPEKSSYRQVSVSDRSSIRVEEIIPAARVAIQTMEVGDFTSTVACFMRLTWAAAAGRLDLVGSSQPIRETTNSLLPLGVRSRVSSTGSNCSSSSEGEVTTLQAGICVKQLFVSIKDTIIAREALSLLVTCLQLRSQQLCSFYSLLSVNDFIIDILLGSPSGEIRRVACDQLYTLSQSDTSAYPDLQKPNLFLLKVVLTAQLPLWSPTSIMRGVNQRLLSQCTEYFDLRCQLLDDLTTSEMEQLQIGPAAMLEDEISWLDNFEPTWTTELETSEADNILLAGHLRLIKTLLSLCGTEKEQFGPSLIQQLLDDFLFRASRIILNSDS-SSSTTASIHDFHPKCSTVSSRLAAYEVLVMLADSSLTNLQLITKELLSMHHQSDPSLSKEFDYLPPVDSRSISGFVGLKNGGATCYMNAVFQQLYMQPGLPEGVLSIEDDTENPEESVFCQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLVDQLDEHLKKIGREQIFKNTFQGIFSDQKICKDCPHRYEREETFMALNLGVTSCQSLEISLDQFVRGEVLDGSNAYYCEKCKEKRTTVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWVLNMEPYTVSGMARQDSSADHGENGRGGEAGSGGSPRKKVTISENYELVGVVVHSGQAHAGHYYSFIKDRRGSARGRWYKFNDNVVEEFDMNDETLEYECFGGEYRPKVYDQSNPYPDVRRRYWNAYMLFYQRISDQNSPVLPKKSRVSIMRQEAEDLSLSAPSSPEISPQSSPRPPRANNDRLTLLTRLVKKGEKKGLFVEKMPARIFQMVRDENLKFMKNRDVYNSDYFSFTLSLASVNATKLKHASYQAMAKTSLQLAVQFLLHTYLRTKKKLRVDTEEWIATVEVLLSKSSEACQWMVQYLVAPEGREIIKICLLECSVREVRVVVATILEKTLESALYFQD--AGLDCLLDMLLSLLDKDVPDNCKNCSQYFSLFSNFAQR-GCGPCQLLLKHSAYRRMLVFLLGPNRQNNQHRRWSSAQAREFLHLHNTLALMVLHTDLTSQRTEAQGVFKQASSGLVAPSSVLMPLHPDINTLLFKADGQAYLMEVMFAMRELSGPLSFLIEMITYSSFCNEPFSLGVLQLLKNHLETAPPHELKNVFQMLLEILMLEDPLQSQRLKFAFESEKGLLALMHQSNNVDSSRCYQCVKFLVTLAQKCSPAKDYFKELSGHWSWAVQWLQKKMSEHYWTPQSNVSNETSTAKTFQRTISAQDTLAYATALLNEKDQSGSSNGSDGSPANENSDRSLRQGSESPMMLGDSRSDLEDVDP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:**************.*..:********************** *** ** ****:** * .* * ... **********:**::*: *********:.:**************:******************:*** *** **:::****:**::**********************************::*****:****** **:.*******************..**********..*.*:** *::*******:*****:*.*:***:***.**:.*:**:*.:***:**:**********:********* . * *:.:******************.:******** **. ** ***********:******************:**:**:***********:*****************************************:***:**:*********************. ***.***********.*:******************* *:*:****:************ **:*******************::**.**********: . .. :*** .*** ******************************************:****::*****.:***..** * *******:*:****.************:*** ************:* **************************************.********.***********.********:** **:*:* ******:********:**********.******.*::****************.**************************************** **:*********************:***************** :**::**********:*******:**:*****. * .***.:***:***:**:*:*****:******** ****:**:***********:*:*.*** .*.*:**:******************:**************************** :*:***:: . .::***:: * * :*********:*:* **:********* ***********************:**:**:...********:*******************************************::*: ***:: ** ::********..**:.**:*:***********:*************************..***:********:*****************:*. *:* * *:*.*:**:******.***: .:*:*****:* ** **::** ***************** ***.* .* ************.***************:***::*::**** *** *:* **************:******** **************:***:**::.**:*****::**:****. *:: *************************:*** .*.***: *************:**.* :.*:: * :********..**************** :***:* ********* **:*:************* ******:***********************.:**::***:**::.** ************************************************:**:**:***:**:**********:*****************:***************************:************** ******** **.:****************************:********:********:: *:***. : *.********: :********:********************..:*:******.*:***::.********************:***.****************:***************::************************* *.*.***::**:**:*************.**:*****************.******.*****:****:**. * .***.*****:***::**********.********::.***** :****:*:*::..****::* ****.******.*********:***::*: .*. **::**:*******:*****:*** **..*.*: * . .***:*** *:*: **** .:*..* *********** ****:**:***:*::***. * *:*** .. ::.*. *:.** ::::*** ::*:.**:***:*:***:*.* *:**:.*..**** **: :*:::*.:*********** **:* *:*::***:* :*:**.**:*:**:****:**:********************..**:**** * ******************:***********.***********************:********:.******.:* *:********:*: :.**:****", "identical_positions": 2066, "similar_positions": 400, "identity": "78.11%" }, { "cls_id": "homologset.oma.815717", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZVK3-1", "uniprot_id": "A0A8I5ZVK3_RAT", "id": "A0A8I5ZVK3-1", "name": "Ubiquitin carboxyl-terminal hydrolase 34", "aln": "MCENCADLVEVLNEISDLEGGDGLQLRKEHTLKIFAYINSWTQRQCLCCFKEYKHLEIFNQVVCALINLVIAQVQVLRDQLCKHCTTTNTDSTWQDESNEAEEPLSIDRECNEGHTERQKSIEKKSNSTGICNLTEEESSKSSDPFSLWNTDEKEKLLLCVAKIFQIQFPLYTAYKHNTHPTIEDISTQESNILGAFCDMNDVEVPLHLLRYVCLFCGKNGLSLMKDCFEYGTPETLPFLIAHAFITVVSNIRIWLHIPAVMQHIIPFRTYVIRYLCKLSDQELRQSAARNMADLMWSTVKEPLDTTLCFDKESLDLAFKYFMSPTLTMRLAGLSQITNQLHTFNDVCNNESLVSDTETSIAKELADWLISNSVIEHIFGPNLHIEIIKQCQVILNFLAAEGRLSTQHIDCIWAAAQLKHCSRYIHDLFPSLIKNLDPVPLRHLLNLVSALEPSVHTEQTLYLASMLIKALWNNALAAKAQLSKQSSFASLLNTNMPIGNKKEEEELRRAAPSPWSPAASPQSSDNSDTHQSGASDIEMDEQLINRNKHVQQRLSDTEESMQGSSDETANSGEDGSSGPGSSSGQSDGSSHEVNSSHASQSAGSPGSELQSEDIADIEALKEEEEEEEEEEEEEEEEEEDEEEEEDDEEEDDDDDDDDHAHNPPKNTCGTEMRNRKLENQAAICLGESQATSERNGTHGGAGKDLVFNTEPLPSVDNRIRMLDACAHSEDPEHDISGEMSSAHIAQGSQESCITRSGDFLGETIGNELFNCRQFIGPQHHHHHHHHHHHHHHHHHHHHHHHDGHMVDDMLSADDVSCSSSQVSAKSEKNMADFDGEESGCEEELVQINSHAELTSHLQQHLPNLASIYHEHLSQGPAVHKHQFSSNAVTDINLDNVCKKGNTLLWDIVQDDDAINLSEGLINEAEKLLCSLVCWFTDRQIRMRFIEGCLENLGNNRSVVISLRLLPKLFGTFQQFGSSYDTHWITMWAEKELNMMKLFFDNLVYYIQGIREGRQKHTLYSHSAEVQVRLQFLTCVFSTLGSPDHFRLSLEQVDILWHCLVEDSECYDDALHWFLNQVRSKDQHAMGMETYKHLFLEKMPQLKPETISMTGLNLFQHLCNLARLATSAYDGGSNSELCGMDQFWGIALRAQSGDVSRAAIQYINSYYINGKTGLEKEQEFISKCMESLMIASSSLEQESHSSLTVIERGLLMLKTHLEAFRRRFAYHLRQWQIEGTGISSHLKALSDKQSLPLRVVCQPAGLPDKMTIEMYPSDQVADLRAEVTHWYENLQKEQINQQAQLQEFGQSSRKGEFPGGLMGPVRMISSGHELTTDYDEKALHELGFKDMQMVFVSLGAPRRERKGEGVQLPASCLPPPQKDNIPMLLLLQEPHLTTLFDLLEMLASFKPPSGKVAVDDSESLKCEELHLHAENLSRRVWELLMLLPTCPNMLTAFQSISDEQSNDGVNWKELLKIKSAHKLLYALEIIEALGKPNRRIRRESTGSYSDLYPDSDDSSEDQVENSKNSWTCKFVAAGGLQQLLEIFNSAMLEPKEHESWTVWQLDCLACLLKLICQFAVDPSDLDLAYHDVFAWSGIAESHRKRAWPGKSRKAAGDHAKSLHVPRLTEVFLVLVQGTSLIQRLMSVAYTYDHLAPRVLKAQSDHRSRHEVSHYSMWLLVSWAHCCSLVKSSLADSDHLQDWLRKLTLLIPETAVRHESCNGLYKLSLSGLDGGDSIHRSFLLLAASTLLKFLPDAQALKPLRIDDYEEEPMLKPGCKEYFWLLCKLVDNIHIKDASQTTLLDLDALARHLADCIRSREILDHLDGNLEDDGLSGLLRLATSVIKHKPPFKFSREGQEFLRDVFNLLFLLPSLKDRRQPKCKSHSSRAAAYDLLVEMVKGSVENYRLVHNWVMAQHMQSHAPYKWDYWPHEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKVEEMSPELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYTEDFLMGKSDRKEGFKDVGDHSKDTESYEYDLIGVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGEMTTKTYDSVTDKFMDFSFEKTHSAYMLFYKRMEPEEENGREYKFDVSSELLEWIWHDNMQFLQDKNIFEHTYFGFMWQLCSCIPSTLPDPKAVSLMTAKLSTSFVLETFIHSKEKPTMLQWIELLTKQFNNSQAACEWFLDRMADDDWWPMQILIKCPNQIVRQMFQRLCIHVIQRLRPVHAHLYLQPGMEDGSDDMDASVEDIGGRSCVTRFVRTLLLIMEHGVKPHSKHLTEYFAFLYEFAKMGEEESQFLLSLQAISTMVHFYMGTKGPENPQVEVLSEEEGEEEEEEEDILSLAEEKYRPAALEKMIALVALLVEQSRSERHLTLSQTDMAALTGGKGFPFLFQHIRDGINIRQTCNLIFSLCRYNNRLAEHIVSMLFTSIAKLTPEAANPFFKLLTMLMEFAGGPPGTPPFASYILQRIWEVIEYNPSQCLDWLAVQTPRNKLAHSWVLQNMENWVERFLLAHNYPRVRTSAAYLLVSLIPSNSFRQMFRSTRSLHIPTRDLPLSPDTTVVLHQVYNVLLGLLSRAKLYVDAAVHGTTKLVPYLSFMTYCLISKTEKLMFSTYFMDLWNLFQPKLSEPAIATNHNKQALLSFWYNVCTECPENIRLIVQNPVVTKNIAFNYILADHDDQDVVLFNRGMLPAYYGILRLCCEQSPAFTRQLASHQNIQWAFKNLTPHASQYPGAVEELFNLMQLFIAQRPDMREEELEDIKQFKKTTISCYLRCLDGRSCWTTLISAFRILLESDEDRLLVVFNRGLILMTESFNTLHMMYHEATACHVTGDLAELLSIFLSVLKSTRPYLQRKDVKQALIQWQERIEFAHKLLTLLNSYSPPELRNACIDVLKELVLLSPHDFLHTLVPFLQHNHCTYHHSNIPMSLGPYFPCRENIKLIGGKSNIRPPRPELNMCLLPTMVETSKGKDDGYDRTLLDFFFSYHQLIHLVCRVAINCEKFTETLVKLSVLVAYEGLPLHLALFPKLWTELCQTQSAMSRNCVKLLCEDPVFAEYIKCILMDERTFLNNNIVYTFMTHFLLKVQSQVFSEANCASLISTLITNLINQYQNLQSDFTNRVEISKASASLNGDLRALALLLSVHTPKQLNPALIPTLQELLNKCRTCLQQRNSLQEQEAKERKTKDDEGATPVKRRRVSSDEEHTVDSCIGDIKTDARDVLTPTSTSDNETRDSSIIDPGTEQDLPSPENGSVKEYRMEGPSSFSEDGSHTRSQHAEEQSNSGRFDSC---KDHSS-KDATLADDESEFPSTSISAVLSDLADLRSCDGQALSSQDPEAAVSLSCGHSRGLISHMQQHDILDTLCRTIESTIHVVTRISGKGNQAAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZQ93-1", "uniprot_id": "UBP34_MOUSE", "id": "Q6ZQ93-1", "name": "Ubiquitin carboxyl-terminal hydrolase 34", "aln": "MCENCADLVEVLNEISDIEGGDGLQLRKEHTLKIFAYINSWTQRQCLCCFKEYKHLEIFNQVVCALINLVIAQVQVLRDQLCKHCTTINIDSTWQDESNQAEEPLSIDRECNEGNTERQKSIEKKSNSTRTCNLTEEESSKSSDPFSLWNTDEKEKLLLCVAKIFQIQFPLYTAYKHNTHPTIEDISTQESNILGAFCDMNDVEVPLHLLRYVCLFCGKNGLSLMKDCFEYGTPETLPFLIAHAFITVVSNIRIWLHIPAVMQHIIPFRTYVIRYLCKLSDQELRQSAARNMADLMWSTVKEPLDTTLCFDKESLDLAFKYFMSPTLTMRLAGLSQITNQLHTFNDVCNNESLVSDTETSIAKELADWLISNNVVEHIFGPNLHIEIIKQCQVILNFLAAEGRLSTQHIDCIWAAAQLKHCSRYIHDLFPSLIKNLDPVPLRHLLNLVSALEPGVHTEQTLYLASMLIKALWNNALAAKAQLSKQSSFASLLNTNMPIGNKKEEEELRRAAPSPWSPAASPQSSDNSDTHQSGASDIEMDEQLINRNKHVQQRLSDTEESMQGSSDETANSGEDGSSGPGSSSGHSDGSSNEVNSSHASQSAGSPGSEVQSEDIADIEALKEEEEEEEEEEEEEEEEDDEEEEDE----EEDDDDDDDHGHNPAKNTCGTELRNRKLENPAGICLGESQGTSERNGTNSGTGKDLVFNTEPLPSVDNRIRMLDACAHSEDPEHGISGEVSSAHLAQGSQEACITRSGDFLGETIGNELFNCRQFIGPQHHHHHHHHHHHHHHHHHHHHHHHDGHMVDDMLSADDVSCSSSQVSAKSEKNMADFDGEESGCEEELVQINSHAELTSHLQQHLPNLASIYHEHLSQGPAVHKHQFSSNAVTDINLDNVCKKGNTLLWDIVQDDDAINLSEGLINEAEKLLCSLVCWFTDRQIRMRFIEGCLENLGNNRSVVISLRLLPKLFGTFQQFGSSYDTHWITMWAEKELNMMKLFFDNLVYYIQGIREGRQKHALYSHSAEVQVRLQFLTCVFSTLGSPDHFRLSLEQVDILWHCLVEDSECYDDALHWFLNQVRSKDQHAMGMETYKHLFLEKMPQLKPETISMTGLNLFQHLCNLARLATSAYDGGSNSELCGMDQFWGIALRAQSGDVSRAAIQYINSYYINGKTGLEKEQEFISKCMESLMIASSSLEQESHSSLTVIERGLLMLKTHLEAFRRRFAYHLRQWQIEGTGISSHLKALSDKQSLPLRVVCQPAGLPDKMTIEMYPSDQVADLRAEVTHWYENLQKEQINQQAQLQEFGQSSRKGEFPGGLMGPVRMISSGHELTTDYDEKALHELGFKDMQMVFVSLGAPRRERKGEGVQLPASCLPPPQKDNIPMLLLLQEPHLTTLFDLLEMLASFKPPSGKVAVDDSESLKCEELHLHAENLSRRVWELLMLLPTCPNMLTAFQNVSDEQSNDGLNWKELLKIKSAHKLLYALEIIEALGKPNRRIRRESTGSYSDLYPDSDDSSEDQVENSKNSWTCKFVAAGGLQQLLEIFNSAILEPKEQESWTVWQLDCLACLLKLICQFAVDPSDLDLAYHDVFAWSGIAESHRKRTWPGKSRKAAGDHAKSLHIPRLTEVFLVLVQGTSLIQRLMSVAYTYDNLAPRVLKAQSDHRSRHEVSHYSMWLLVSWAHCCSLVKSSLADSDHLQDWLKQLTLLIPETAVRHESCNGLYKLSLSGLDGGDSIHRSFLLLAASTLLKFLPDAQALKPPRIDDYEEEPLLKPGCKEYFWLLCKLVDNIHIKDASQTTLLDLDALARHLADCIRSREILDHLDGSIEDDGLSGLLRLATSVIKHKPPFKFSREGQEFLRDIFNLLFLLPSLKDRRQPKCKSHSCRAAAYDLLVEMVKGSVENYRLIHNWVMAQHMQSHAPYKWDYWPHEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKVEEMSPELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYTEDFLMGKSDRKEGFKDVGDRSKDTESYEYDLIGVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGEMTTKTYDSVTDKFMDFSFEKTHSAYMLFYKRMEPEEENGREYKFDVSSELLEWIWHDNMQFLQDKNIFEHTYFGFMWQLCSCIPSTLPDPKAVSLMTAKLSTSFVLETFIHSKEKPTMLQWIELLTKQFNNSQAACEWFLDRMADDDWWPMQILIKCPNQIVRQMFQRLCIHVIQRLRPVHAHLYLQPGMEDGSDDMDASVEDIGGRSCVTRFVRTLLLIMEHGVKPHSKHLTEYFAFLYEFAKMGEEESQFLLSLQAISTMVHFYMGTKGPENPQVEVLSEEEGEEEEEEEDILSLAEEKYRPAALEKMIALVALLVEQSRSERHLTLSQTDMAALTGGKGFPFLFQHIRDGINIRQTCNLIFSLCRYNNRLAEHIVSMLFTSIAKLTPEAANPFFKLLTMLMEFAGGPPGMPPFASYILQRIWEVIEYNPSQCLDWLAVQTPRNKLAHSWVLQNMENWVERFLLAHNYPRVRTSAAYLLVSLIPSNSFRQMFRSTRSLHIPTRDLPLSPDTTVVLHQVYNVLLGLLSRAKLYVDAAVHGTTKLVPYLSFMTYCLISKTEKLMFSTYFMDLWNLFQPKLSEPAIATNHNKQALLSFWYNVCADCPENIRLIVQNPVVTKNIAFNYILADHDDQDVVLFNRGMLPAYYGILRLCCEQSPAFTRQLASHQNIQWAFKNLTPHASQYPGAVEELFNLMQLFIAQRPDMREEELEDIKQFKKTTISCYLRCLDGRSCWTTLISAFRILLESDEDRLLVVFNRGLILMTESFNTLHMMYHEATACHVTGDLVELLSIFLSVLKSTRPYLQRKDVKQALIQWQERIEFAHKLLTLLNSYSPPELRNACIDVLKELVLLSPHDFLHTLVPFLQHNHCTYHHSNIPMSLGPYFPCRENIKLIGGKSNIRPPRPELNMCLLPTMVETSKGKDDVYDRMLLDYFFSYHQFIHLLCRVAINCEKFTETLVKLSVLVAYEGLPLHLALFPKLWTELCQTQSAMSKNCIKLLCEDPVFAEYIKCILMDERTFLNNNIVYTFMTHFLLKVQSQVFSEANCASLISTLITNLINQYQNLQSDFTNRVEISKASAALNGDLRALALLLSVHTPKQLNPALIPTLQELLNKCRTCLQQRNSLQEQEAKERKTKDDEGATPVKRRRVSSDEEHTVDSCIGDIKTETREVLTPTSTSDNETRDSSIIDPGTEQDLPSPENSSVKEYRMEGPSSFSEDGSHIRSQHAEEQSNNGRFDDCKEFKDHCS-KDTTLAEDESEFPSTSISAVLSDLADLRSCDGQALSSQDPEAAVSLSCGHSRGLISHMQQHDILDTLCRTIESTIHVVTRISGKGNQAAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q70CQ2-1", "uniprot_id": "UBP34_HUMAN", "id": "Q70CQ2-1", "name": "Ubiquitin carboxyl-terminal hydrolase 34", "aln": "MCENCADLVEVLNEISDVEGGDGLQLRKEHTLKIFTYINSWTQRQCLCCFKEYKHLEIFNQVVCALINLVIAQVQVLRDQLCKHCTTINIDSTWQDESNQAEEPLNIDRECNEGSTERQKSIEKKSNSTRICNLTEEESSKSSDPFSLWSTDEKEKLLLCVAKIFQIQFPLYTAYKHNTHPTIEDISTQESNILGAFCDMNDVEVPLHLLRYVCLFCGKNGLSLMKDCFEYGTPETLPFLIAHAFITVVSNIRIWLHIPAVMQHIIPFRTYVIRYLCKLSDQELRQSAARNMADLMWSTVKEPLDTTLCFDKESLDLAFKYFMSPTLTMRLAGLSQITNQLHTFNDVCNNESLVSDTETSIAKELADWLISNNVVEHIFGPNLHIEIIKQCQVILNFLAAEGRLSTQHIDCIWAAAQLKHCSRYIHDLFPSLIKNLDPVPLRHLLNLVSALEPSVHTEQTLYLASMLIKALWNNALAAKAQLSKQSSFASLLNTNIPIGNKKEEEELRRTAPSPWSPAASPQSSDNSDTHQSGGSDIEMDEQLINRTKHVQQRLSDTEESMQGSSDETANSGEDGSSGPGSSSGHSDGSSNEVNSSHASQSAGSPGSEVQSEDIADIEALKEE------------------------------DEDDDHGHNPPKSSCGTDLRNRKLESQAGICLGDSQGMSERNGTSSGTGKDLVFNTESLPSVDNRMRMLDACSHSEDPEHDISGEMNATHIAQGSQESCITRTGDFLGETIGNELFNCRQFIGPQHHHHHHHHH-----------HHHDGHMVDDMLSADDVSCSSSQVSAKSEKNMADFDGEESGCEEELVQINSHAELTSHLQQHLPNLASIYHEHLSQGPVVHKHQFNSNAVTDINLDNVCKKGNTLLWDIVQDEDAVNLSEGLINEAEKLLCSLVCWFTDRQIRMRFIEGCLENLGNNRSVVISLRLLPKLFGTFQQFGSSYDTHWITMWAEKELNMMKLFFDNLVYYIQTVREGRQKHALYSHSAEVQVRLQFLTCVFSTLGSPDHFRLSLEQVDILWHCLVEDSECYDDALHWFLNQVRSKDQHAMGMETYKHLFLEKMPQLKPETISMTGLNLFQHLCNLARLATSAYDGCSNSELCGMDQFWGIALRAQSGDVSRAAIQYINSYYINGKTGLEKEQEFISKCMESLMIASSSLEQESHSSLMVIERGLLMLKTHLEAFRRRFAYHLRQWQIEGTGISSHLKALSDKQSLPLRVVCQPAGLPDKMTIEMYPSDQVADLRAEVTHWYENLQKEQINQQAQLQEFGQSNRKGEFPGGLMGPVRMISSGHELTTDYDEKALHELGFKDMQMVFVSLGAPRRERKGEGVQLPASCLPPPQKDNIPMLLLLQEPHLTTLFDLLEMLASFKPPSGKVAVDDSESLRCEELHLHAENLSRRVWELLMLLPTCPNMLMAFQNISDEQSNDGFNWKELLKIKSAHKLLYALEIIEALGKPNRRIRRESTGSYSDLYPDSDDSSEDQVENSKNSWSCKFVAAGGLQQLLEIFNSGILEPKEQESWTVWQLDCLACLLKLICQFAVDPSDLDLAYHDVFAWSGIAESHRKRTWPGKSRKAAGDHAKGLHIPRLTEVFLVLVQGTSLIQRLMSVAYTYDNLAPRVLKAQSDHRSRHEVSHYSMWLLVSWAHCCSLVKSSLADSDHLQDWLKKLTLLIPETAVRHESCSGLYKLSLSGLDGGDSINRSFLLLAASTLLKFLPDAQALKPIRIDDYEEEPILKPGCKEYFWLLCKLVDNIHIKDASQTTLLDLDALARHLADCIRSREILDHQDGNVEDDGLTGLLRLATSVVKHKPPFKFSREGQEFLRDIFNLLFLLPSLKDRQQPKCKSHSSRAAAYDLLVEMVKGSVENYRLIHNWVMAQHMQSHAPYKWDYWPHEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKIEEMSPELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYTEDFLMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGEMTTKTYDSVTDKFMDFSFEKTHSAYMLFYKRMEPEEENGREYKFDVSSELLEWIWHDNMQFLQDKNIFEHTYFGFMWQLCSCIPSTLPDPKAVSLMTAKLSTSFVLETFIHSKEKPTMLQWIELLTKQFNNSQAACEWFLDRMADDDWWPMQILIKCPNQIVRQMFQRLCIHVIQRLRPVHAHLYLQPGMEDGSDDMDTSVEDIGGRSCVTRFVRTLLLIMEHGVKPHSKHLTEYFAFLYEFAKMGEEESQFLLSLQAISTMVHFYMGTKGPENPQVEVLSEEEGEEEEEEEDILSLAEEKYRPAALEKMIALVALLVEQSRSERHLTLSQTDMAALTGGKGFPFLFQHIRDGINIRQTCNLIFSLCRYNNRLAEHIVSMLFTSIAKLTPEAANPFFKLLTMLMEFAGGPPGMPPFASYILQRIWEVIEYNPSQCLDWLAVQTPRNKLAHSWVLQNMENWVERFLLAHNYPRVRTSAAYLLVSLIPSNSFRQMFRSTRSLHIPTRDLPLSPDTTVVLHQVYNVLLGLLSRAKLYVDAAVHGTTKLVPYFSFMTYCLISKTEKLMFSTYFMDLWNLFQPKLSEPAIATNHNKQALLSFWYNVCADCPENIRLIVQNPVVTKNIAFNYILADHDDQDVVLFNRGMLPAYYGILRLCCEQSPAFTRQLASHQNIQWAFKNLTPHASQYPGAVEELFNLMQLFIAQRPDMREEELEDIKQFKKTTISCYLRCLDGRSCWTTLISAFRILLESDEDRLLVVFNRGLILMTESFNTLHMMYHEATACHVTGDLVELLSIFLSVLKSTRPYLQRKDVKQALIQWQERIEFAHKLLTLLNSYSPPELRNACIDVLKELVLLSPHDFLHTLVPFLQHNHCTYHHSNIPMSLGPYFPCRENIKLIGGKSNIRPPRPELNMCLLPTMVETSKGKDDVYDRMLLDYFFSYHQFIHLLCRVAINCEKFTETLVKLSVLVAYEGLPLHLALFPKLWTELCQTQSAMSKNCIKLLCEDPVFAEYIKCILMDERTFLNNNIVYTFMTHFLLKVQSQVFSEANCANLISTLITNLISQYQNLQSDFSNRVEISKASASLNGDLRALALLLSVHTPKQLNPALIPTLQELLSKCRTCLQQRNSLQEQEAKERKTKDDEGATPIKRRRVSSDEEHTVDSCISDMKTETREVLTPTSTSDNETRDSSIIDPGTEQDLPSPENSSVKEYRMEVPSSFSEDMSNIRSQHAEEQSNNGRYDDCKEFKDLHCSKDSTLAEEESEFPSTSISAVLSDLADLRSCDGQALPSQDPEVALSLSCGHSRGLFSHMQQHDILDTLCRTIESTIHVVTRISGKGNQAAS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****************:*****************:*************************************************** * *********:*****.******** ************** ******************.******************************************************************************************************************************************************************************************************************************.*:******************************************************************************.*****************************************:*************:***********************.************.*************************************:*****:*****************:************** *:****.***.*.:***::******. *.****:**. ****** .*:*********.*******:******:*******.****:.::*:******:****:******************************* ******************************************************************************.******.**************************:**:********************************************************************************************* :*******:***************************************************************************************************************** *********************************************************************** *******************************************************************************************************.****************************************************************************************************************:***************************** ***.:********.*************************************************************:******************.:*****:************************************************:**************.**:****************************:**************************************************::***************.****************:*********************** *********:*************************************************** **.:*****:*********:******************:*************:********.*********************:*******************************************************************************************************************************:*****************************************************************************************************************************************:******:*.*:***:**********************************************************************************************************************************************************************************************************************************************************************:********************************************************************************************************************************************************************************************************************* ***************************************************************************************************************************************:*****************************************************::***************************************************************************************************************************************************************************************.***************************************************************************************************************************************** *** ***:******:***:************************************************:**:***************************************************.**********.*********:**********:********************************.******************************:*****************.*:**::*:*******************************.******** ******* *: **********.**:*.* ** . **:***::***************************.*****.*:**********:***********************************", "identical_positions": 3409, "similar_positions": 111, "identity": "95.04%" }, { "cls_id": "homologset.oma.815750", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "G5E870-1", "uniprot_id": "TRIPC_MOUSE", "id": "G5E870-1", "name": "E3 ubiquitin-protein ligase TRIP12", "aln": "MSNRPNNNPGGSLRRSQRNTAGAQPQDDSIGGR-SCSSSSAVIVPQPEDPDRANTSERQKTGQVPKKDNSRGVKRSASPDYNRTNSPSSAKKPRAFQHIESFSETNKP-------------------HSKSKKRHLDQEQQLKSAQLPSTSKAHTRKSVAAGSSRNQKRKRTES-SCVKSGSGSEST--GAE---------ERSAKPIKLASKSATSAKAGCSTITDSSSA-----ASTSSSSSAIASASSTVPAGARVKQGKDQNKARRSRSASSPSPRRSSREKEQSKTGGSSKFDWAARFSPKVSLPKTKLSLPGSSKSETS-KPGPSGLQAKLASLRKSTKKRSESPPAELPSLRRSTRQKTTGSCASTSRRGSGLGKRGAAEARRQEKMADPESNQETVNSSAARTDEAPQGAAASSSVAGAVGMTTSGESESDDSEMGRLQALLEARGLPPHLFGPLGPRMSQLFHRTIGSGASSKAQQLLQGLQAS-DESQQLQAVIEMCQLLVMGNEETLGGFPVKSVVPALITLLQMEHNFDIMNHACRALTYMMEALPRSSAVVVD--AIPVFLEKLQVIQCIDVAEQALTALEMLSRRHSKAILQAGGLADCLLYLEFFSINAQRNALAIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLVDNFQHEENLLQQVASKDLLTNVQQLLVVTPP-----ILSSGMFIMVVRMFSLMCSNCPTLAVQLMKQNIAETLHFLLCGASNGSCQEQIDLVPRSPQELYELTSLICELMPCLPKEGIFAVDTMLKKGNAQNTDGAIWQWRDDRGLWHPYNRIDSRIIEAAHQVGEDEISLSTLGRVYTIDFNSMQQINEDTGTARAIQRKPNPLANSNTSG-YSELKKDDARAQLMKEDPELAKSFIKTLFGVLYEVYSSSAGPAVRHKCLRAILRIIYFADAELLKDVLKNHAVSSHIASMLSSQDLKIVVGALQMAEILMQKLPDIFSVYFRREGVMHQVKHLAESESLLTSPPK------------------------------------ACTNGSGSLGSTTPASSGTATAATNASADLGSPSLQHSRDDSLDLSPQG--------------------------------RLSDVLKRKRLPKRG---------------PRRPKYSPPRDDDKVDNQAKSPTT----------------------------------TQSPKSSFLASLNPKTWGRLSAQSNSNNIEPARTAGVSGLARAASKDTISN------NREKIKGWIKEQAHKFVERYFSSENMDGSNP-----------ALNVLQRLCAATEQLNLQVDGGAECLVEIRSIVSESDVSSFEIQHSGFVKQLLLYLTSKNEKDAVGREIRLKRFLHVFFSSPLPGEEPVG----RVEP-------VGHAPLLALVHKMNNCLSQMEQFPVKVHDFPSGNGAGGSFSLNRGSQALKFFNTHQLKCQLQRHPDCAN----VKQWKGGPVKIDPLALVQAIERYLVVRGYGRVREDDEDSDDDGSDEE------------------------------------------------------IDESLAAQFLN-----------------------------------SGNVRHRLQFYIGEHLLPYNMTVYQAVRQFSVQAEDERESTDDESNPLGRAGIWTKTHTIWYKPVREDEESTKDCVGGKRG-----------RAQTAPTKTSPRNAKKHDELWHDGVCPSVANPLEVYLIPTPPENITF-EDPSLDVILLLRVLHAISRYWYYLYDN-----------------AMCKEIIPTSEFINSKLTAKANRQLQDPLVIMTGNIPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTN------PEINQSDSQDSRVAPRLDRKKRTVNREELLKQAESVMQDLGSSRAMLEIQYENEVGTGLGPTLEFYALVSQELQRADLCLWRGEE----------VTLSNPKGSQEG---------------------------------------------------TKYIQNLQGLFALPFGRTAKP---AHIAKVKMKFRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLEDIVRQKKRLEQDKSQTKESLQYALETLTMNGCSVEDLGLDFTLPGFPNIELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVCRQFDSFRDGFESVFPLCHLQYFYPEELDQLLCGSKA---DTWDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFES----------TENPDDFLPSVMTCVNYLKLPDYSSIDIMRDKLLIAAREGQQSFHLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LP64-1", "uniprot_id": "TRIPC_RAT", "id": "F1LP64-1", "name": "E3 ubiquitin-protein ligase TRIP12", "aln": "MSNRPNNNPGGSLRRSQRNTAGAQPQDDSIGGR-SCSSSSAVIVPQPEDPDRANTSERQKTGQVPKKDNSRGVKRSASPDYNRTNSPSSAKKPRAFQHIESLSETNKP-------------------PSKSKKRHLDQEQQLKSAQLPSTSKAHTRKSVAAGSSRSQKRKRTES-SCVKSGSGSEST--GAE---------ERSAKPTKLASKSATSAKAGCSTITDSSSA-----ASTSSSSSAVASASSTVPAGARVKQGKDQNKARRSRSASSPSPRRSSREKEQSKTGGSSKFDWAARFSPKVSLPKTKLSLPGSSKSETS-KPGPSGLQAKLASLRKSTKKRSESPPAELPSLRRSTRQKTTGSCASTSRRGSGLGKRGAAEARRQEKMADPEGNQETVNSSAARTDEAPQGAAASSSVAGAVGMTTSGESESDDSEMGRLQALLEARGLPPHLFGPLGPRMSQLFHRTIGSGASSKAQQLLQGLQAS-DESQQLQAVIEMCQLLVMGNEETLGGFPVKSVVPALITLLQMEHNFDIMNHACRALTYMMEALPRSSAVVVD--AIPVFLEKLQVIQCIDVAEQALTALEMLSRRHSKAILQAGGLADCLLYLEFFSINAQRNALAIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLVDNFQHEENLLQQVASKDLLTNVQQLLVVTPP-----ILSSGMFIMVVRMFSLMCSNCPTLAVQLMKQNIAETLHFLLCGASNGSCQEQIDLVPRSPQELYELTSLICELMPCLPKEGIFAVDTMLKKGNAQNTDGAIWQWRDDRGLWHPYNRIDSRIIEAAHQVGEDEISLSTLGRVYTIDFNSMQQINEDTGTARAIQRKPNPLANTNTSG-YSDLKKDDARAQLMKEDPELAKSFIKTLFGVLYEVYSSSAGPAVRHKCLRAILRIIYFADAELLKDVLKNHAVSSHIASMLSSQDLKIVVGALQMAEILMQKLPDIFSVYFRREGVMHQVKHLAESESLLTSPPK------------------------------------ACTNGSGSLGSTTPASSGTATAATNASADLGSPSLQHSRDDSLDLSPQG--------------------------------RLSDVLKRKRLPKRG---------------PRRPKYSPPRDDDKVDNQAKSPTT----------------------------------TQSPKSSFLASLNPKTWGRLSAQSNSNNIEPARTAGVSGLARAASKDTISN------NREKIKGWIKEQAHKFVERYFSSENMDGSNP-----------ALNVLQRLCAATEQLNLQVDGGAECLVEIRSIVSESDVSSFEIQHSGFVKQLLLYLTSKSEKDAVSREIRLKRFLHVFFSSPLPGEEPVG----RVEP-------VGHAPLLALVHKMNNCLSQMEQFPVKVHDFPSGNGSGGSFSLNRGSQALKFFNTHQLKCQLQRHPDCAN----VKQWKGGPVKIDPLALVQAIERYLVVRGYGRVREDDEDSDDDGSDEE------------------------------------------------------IDESLAAQFLN-----------------------------------SGNVRHRLQFYIGEHLLPYNMTVYQAVRQFSVQAEDERESTDDESNPLGRAGIWTKTHTIWYKPVREDEESSKDCVGGKRG-----------RAQTAPTKTSPRNAKKHDELWHDGVCPSVANPLEVYLIPTPPENITF-EDPSLDVILLLRVLHAISRYWYYLYDN-----------------AMCKEIIPTSEFINSKLTAKANRQLQDPLVIMTGNIPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTN------PEINQSDSQDSRVAPRLDRKKRTVNREELLKQAESVMQDLGSSRAMLEIQYENEVGTGLGPTLEFYALVSQELQRADLGLWRGEE----------VTLSNPKGSQEG---------------------------------------------------TKYIQNLQGLFALPFGRTAKP---AHIAKVKMKFRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLEDIVRQKKRLEQDKSQTKESLQYALETLTMNGCSVEDLGLDFTLPGFPNIELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVCRQFDSFRDGFESVFPLSHLQYFYPEELDQLLCGSKA---DTWDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFES----------TENPDDFLPSVMTCVNYLKLPDYSSIEIMRDKLLIAAREGQQSFHLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E1B7Q7-1", "uniprot_id": "TRIPC_BOVIN", "id": "E1B7Q7-1", "name": "E3 ubiquitin-protein ligase TRIP12", "aln": "MSNRPNNNPGGSLRRSQRNTAGAQPQDDSIGGR-SCSSSSVVIVPQPEDPDRANTSEKQKTGQVPKKDNSRGVKRSASPDYNRTNSPSSAKKPKALQHTESPSETSKP-------------------HSKSKKRHLDQEPQLKSAPSPSTSKAHTRKSGAAAGSRSQKRKRTES-SCIKSASVSEAT--GAE---------ERSAKPTKLASKSAASAKAGCSTITDSSSA-----ASTSSSSSAVASASSAVPPGARVKQGKDQNKARRSRSASSPSPRRSSREKEQSKTGGSSKFDWAARFSPKVSLPKTKLSLPGSSKSETS-KPGPSGLQAKLASLRKSTKKRSESPPAELPSLRRSTRQKTTGSCASASRRGSGLGKRGAAEARRQEKMADPEGNQETVNSSAARTDETPQGAAG------AVGMTTSGESESDDSEMGRLQALLEARGLPPHLFGPLGPRMSQLFHRTIGSGASSKAQQLLQGLQAS-DESQQLQAVIEMCQLLVMGNEETLGGFPVKSVVPALITLLQMEHNFDIMNHACRALTYMMEALPRSSAVVVD--AIPVFLEKLQVIQCIDVAEQALTALEMLSRRHSKAILQAGGLADCLLYLEFFSINAQRNALAIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLVDNFQHEENLLQQVASKDLLTNVQQLLVVTPP-----ILSSGMFIMVVRMFSLMCSNCPTLAVQLMKQNIAETLHFLLCGASNGSCQEQIDLVPRSPQELYELTSLICELMPCLPKEGIFAVDTMLKKGNAQNTDGAIWQWRDDRGLWHPYNRIDSRIIE---------------------------QINEDTGTARAIQRKPNPLANTNTSG-YSELKKDDARAQLMKEDPELAKSFIKTLFGVLYEVYSSSAGPAVRHKCLRAILRIIYFADAELLKDVLKNHAVSSHIASMLSSQDLKIVVGALQMAEILMQKLPDIFSVYFRREGVMHQVKHLAESESLLTSPPK------------------------------------ACTNGSGSLGSTPSVNSGTATAATNASADLGSPSLQHSRDDSLDLSPQG--------------------------------RLSDVLKRKRLPKRG---------------SRRPKYSPPRDDDKVDNQAKSPTT----------------------------------TQSPKSSFLASLNPKTWGRLSAQSNSNNIEPARTAGVSGLARAASKDTISN------NREKIKGWIKEQAHKFVERYFSSENMDGSNP-----------ALNVLQRLCAATEQLNLQVDGGAECLVEIRSIVSESDVSSFEIQHSGFVKQLLLYLTSKSEKDAVSREIRLKRFLHVFFSSPLPGEEPIE----RVEP-------VGNAPLLALVHKMNNCLSQMEQFPVKVHDFPSGNGTGGSFSLNRGSQALKFFNTHQLKCQLQRHPDCAN----VKQWKGGPVKIDPLALVQAIERYLVVRGYGRVREDDEDSDDDGSDEE------------------------------------------------------IDESLAAQFLN-----------------------------------SGNVRHRLQFYIGEHLLPYNMTVYQAVRQFSIQAEDERESTDDESNPLGRAGIWTKTHTIWYKPVREDEESNKDCVGGKRG-----------RAQTAPTKTSPRNAKKHDELWNDGVCPSVSNPLEVYLIPTAPENITF-EDPSLDVILLLRVLHAVSRYWYYLYDN-----------------AMCKEIIPTSEFINSKLTAKANRQLQDPLVIMTGNIPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTN------PEINQSDSQDSRVAPRLDRKKRTVNREELLKQAESVMQDLGSSRAMLEIQYENEVGTGLGPTLEFYALVSQELQRADLGLWRGEE----------VTLSNPKGSQEG---------------------------------------------------TKYIQNLQGLFALPFGRTAKP---AHIAKVKMKFRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLEDIVRQKKRLEQDKSQTKESLQYALETLTMNGCSVEDLGLDFTLPGFPNIELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVSRQFDSFRDGFESVFPLSHLQYFYPEELDQLLCGSKA---DTWDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFES----------TENPDDFLPSVMTCVNYLKLPDYSSLEIMREKLLMAAREGQQSFHLS", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A8V0ZS27-1", "uniprot_id": "A0A8V0ZS27_CHICK", "id": "A0A8V0ZS27-1", "name": "E3 ubiquitin-protein ligase", "aln": "MSNRPNNNPGGSLRRSQRNTAGAQPQDDAAGGR-GCSSS-AVLIPQ-EDSERVSTSEKQKTGQVPKKDNSRGVKRSASPDYSRTNSPSSAKKPKALQHAETSSESNKP-------------------HTKSKRRHLDQE-QQKSTQLPSTSKAHTRKGGAAGSSRSQKRKRTESTSCIKSRSAVEST--GAE---------EKSAKSSKLASKSVTSAKAGCSTITDSSSS-----ASTSSSSSAVASASSTVPQGARVKQGKDQNKARRSRSASSPSPRRSSRDKEQSKTGGSSKFDWAARFSPKVSLPKTKLSLPGSSKSETS-KPGPSGLQAKLASLRKSTKKRSESPPAELPSLRRSTRQKTTGSCASTSRRGSGLGKRGAAEARRQEKMADPDNNQDGVNSSAARTDETPQGAAASSSVAGAVGMTTSGESESDDSEMGRLQALLEARGLPPHLFGPLGPRMSQLFHRTIGSGASSKAQQLLQGLQAT-DESQQLQAVIEMCQLLVMGNEETLGGFPVKSVVPALITLLQMEHNFDIMNHACRALTYMMEALPRSSAVVVD--AIPVFLEKLQVIQCIDVAEQALTALEMLSRRHSKAILQAGGLADCLLYLEFFSINAQRNALAIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLVDNFQHEENLLQQVASKDLLTNIQQLLVVTPP-----ILSSGMFIMVVRMFSLMCSNCPTLAVQLMKQNIAETLHFLLCGASNGSCQEQIDLVPRSPQELYELTSLICELMPCLPKEGIFAVDTMLKKGNAQNTDGAIWQWRDDRGLWHPYNRIDSRIIEAAHQVGEDEISLSTLGRVYTIDFNSMQQINEDTGTARAIQRKPNPLANTNTSG-HSELKKDDARAQLMKEDPELAKSFIKTLFGVLYEVYSSSAGPAVRHKCLRAILRIIYFADAELLKDVLKNHAVSSHIASMLSSQDLKIVVGALQMAEILMQKLPDIFSVYFRREGVMHQVKNLAESEALLTSPPK------------------------------------VCTNGSGTLGTTTTISTGTATAATNAAADLGSPSLQHSREDSLDLSPQG--------------------------------RLSDVLKRKRLPKRG---------------PRRPKYSPPRDDDKVDNQAKSPTT----------------------------------TQSPKSSFLASLNPKTWGRLSTQSNSNNIEPARTAGVSGLARAASKDTISN------NREKIKGWIKEQAHKFVDRYFSSENMDGSNP-----------ALNVLQRLCTATEQLNLQVDGGTECLVEIRSIVSESDVSSFEIQHSGFVKQLLLYLTSKSEKDAVSRDIRLKRFLHVFFSSPLPGEEPLG----RLEP-------LENAPLLALVHKMNNCLSQMEQFPVKVHDFPSGNGTGSSFSLNRGSQALKFFNTHQLKCQLQRHPDCAN----VKQWKGGPVKIDPLALVQAIERYLVVRGYGRVREDDEDSDDDGSDEE------------------------------------------------------IDESLAAQFLN-----------------------------------SGNVRHRLQFYIGDHLLPYNMTVYQAVKLYSLQAEEERESTDDESNPLGRAGIWTKTHTIWYKPVREDEDGNKDCVGGKRG-----------RAQTAPTKTSPRNSKKHDELWHDGVCPSVLNPLEVYLISTPPENITF-EDPSLDVILLLRVLHAISRYWYYLYDN-----------------AICKEIIPTSEFINSKLTAKANRQLQDPLVIMTGNIPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTN------PEINQSDSQDSRVAPRLDRKKRTVNRDELLKQAESVMQDLGSSRAMLEIQYENEVGTGLGPTLEFYALVSQELQRADLGLWRGEE----------VTLANPKGSQEG---------------------------------------------------TKYIHNLQGLFALPFGRTAKP---AHIAKVKMKFRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFSIDPVVAKSIYHLEDIVRQKKRLEQDKTQTKESLQYALETLTMNGCSVEDLGLDFTLPGFPNIELKKGGKDTPVTIHNLEEYLRLVIFWALNEGVARQFDSFRDGFESVFPLSHLQYFYPEELEQLLCGSKT---DTWDAKTLMECCRPDHGYTHDSRAVKYLFEILSSFDSEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFES----------TENPDDFLPSVMTCVNYLKLPDYSTIEIMREKLLIAAREGQQSFHLS", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "F1RCR6-1", "uniprot_id": "TRIPC_DANRE", "id": "F1RCR6-1", "name": "E3 ubiquitin-protein ligase TRIP12", "aln": "MSNRPNSNPGGSLRRSQRNTAAAQPIDHTLAGRNSLSLSVGSLSIPDPDLEAAGTSGQQGR---REGSSTRALKRSSVSEPNITFSPSPAKRPKVVSSHFSDSSASGPSAPAISPEVTEPRKAPASVSTKSKKRRLAAEPAPARALSKKSSSYPGPSGASSTPSQKRKKADATLLSSSSSSSLPSSS--SAAGPLPPRSEASRAAKPTKLASKSAASAKAGCSTVTDSSSSSASSSSSSSSSSSAATGTNSCAPQGARLKQGKDQSKARRSRSASSPSPRRSSRDKEQSKAAGSSKFDWASRFNSKVNLPKPKLSLPGSAKAETSSKPGPSGLQAKLASLRKSTKKRSESPPAELPSCRRSTRQKTTGSCASTSRRGSGLGKRGAAEARRQEKMADSDNNQDGANSSAARTEETPQGASASSSVAGAVGMTTSGESESDDSEMGRLQALLEARGLPPHLFGPFGPRMSQLFHRTIGSGASSKAQQLLQGLQATGDESQQLQAAIEMCQLLVMGNEETLGGFPVKSVVPALITLLQMEHNFDIMNHASRALTYMMEALPRSSAVVVD--AIPVFLEKLQVIQFIDVAEQALTALEMLSRRHSKAILQAGGLADCLLYLEFFSINAQRNALAIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLVDNFQHEENLLQQVASRDLLTNIQQLLVLTPP-----VLSSGMFIMVVRMFSLMCSNCPCLAVQLMKQNIAETLRFLLCGASNGSCQEQIDLVPRSPQELYELTSLICELMPCLPREGIFAVDAMLKKGSAQTTEGAIWQWRDDRGLWHPYNRIDSRIIE---------------------------QINEDTGTARAIQRKPNPLANPNTGG-HLEVRREDARAQLMKEDPELAKCFIKTLFGVLYEVYSSSAGPAVRHKCLRAILRIIYFADAELLKDVLRNHAVSSHIASMLSSQDLKIVVGSLQMAEILMQKLPDVFSVYFRREGVMHQVKNLAESEVFLTSPPK------------------------------------ACTSGTASLCTTT-ITTATTTAASNVTPDLGSPSFQHSMDDSLDLSPQG--------------------------------RLSDVLKRKRLPKRG---------------PRRPKYSPPRDDDKVDNQAKSPTT----------------------------------TQSPKSSFLASLNPKTWGKLGTQANSANSEPSRTAGVSGLARVPPKDSVSN------NRDKIKAWIKEQASKFVERYFNSESVDGSNP-----------ALNVLQRLCTATEQLNLQMDSGVECLEEISSIVSESDVSSFEIQHSGLVKQLLLYLTSNSERDTISRDERIKRFLHVFFGCPIPGQEPPG----RLDP-------TENGPLLALVHKMNNCLSQMEQFPVKVHDFPSGNGNGS-----RGSQALKFFNTHQLKCQLQRHPDCTN----VKQWKGGPVKIDPLALVQAIERYLVVRGYGRIREEDEDSDDDGSDDE------------------------------------------------------IDESLAAQFLN-----------------------------------SGSVRHRLQFYIGEHLLPYNMTVYQAVRQFSLQAEEERESTDDEANPLGRAGIWTKTHTVWYKPVREDEEGCKDAVGGKRG-----------RAQTAPTKTSPRNAKKQDELWHEGVCPSVANPLETYLICDPPEGITF-DDPSMEVILLLRVLHSISRYWFYLYDN-----------------AACKEIIPTGEFINSKLTAKANRQLQDPLVIMTGNIPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTN------PEINQSDSQDSRVAPRLDRKKRTINRDELLKQAESVMQDLGSSRAMLEIQYENEVGTGLGPTQEFYALVSQELQRADLGLWRGEE----------VTLSNPKGSQEG---------------------------------------------------TKYMFSSRGLFAVPFGRTTKP---AHIAKIKMKFRFLGKLMAKAIMDFRLLDLPLGLPFYKWMLRHESSISSHDLVNIDPGVAKSIQHLEDIIRQKKRIEQDRSHTRETLQQALESLNMNGCSVEDLGLDFTLPGFPNIELKKGGKDVPVTIHNLEDYLRLVVYWTLNEGVLRQFESFREGFESVFPLHHLQYFYPEELDQLLCGSKS---ESWDVKTLMECCRPDHGYTHDSRAVRFLFEVLSSFDAEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFES----------TENPDDFLPSVMTCVNYLKLPDYSSIEIMREKLLIAAREGQQSFHLS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6WWW4-1", "uniprot_id": "UPL3_ARATH", "id": "Q6WWW4-1", "name": "E3 ubiquitin-protein ligase UPL3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------METRSRKRAEATSAAPSSSSSSPPPPP-------------------------------------SASG------PTTRSKRARLSSSSSSSLAPTPPSSSTTTRSRSSRSAAAAAPMDTSTDSSGFRRGGRG--------------------------------------------NRGNNNDNSDKGKEKEHDVRIRERERER------DRAREQLNMDAAAAAARSADEDDDNDSEDGNGG-----FMHPNMSSASSALQGLLRKLGAG-----------LDDLLPSSGIG----------------SASSSHLNGRMKKILSGLRAEGEEGKQVEALTQLCEMLSIGTEDSLSTFSVDSFVPVLVGLLNHESNPDIMLLAARALTHLCDVLPSSCAAVVHYGAVSCLVARLLTIEYMDLAEQSLQALKKISQEHPTACLRAGALMAVLSYLDFFSTGVQRVALSTAANMCKKLPSDASDYVMEAVPLLTNLLQYHDSKVLEYASICLTRIAEAFAPYPEKLDELCNHGLVTQAASLISTSNSGGGQASLSVSTYTGLIRLLSTCASGSPLGFRTLLLLGISSILKDILLGSGVSANASVSPALSRPADQIYEIVNLANELLPPLPEG----------------------------------------------------------------------VISLPTSTNALVKGSCQKKSSPSTSGKQEDILKISPREKLLGDQPELLQQFGLDLLPVLVQIYGSSVNGTIRHKCLSVIGKLMYFSSSEMIQSLIGDTNISSFLAGVLAWKDPQVLVPALQVAEILMEKLPETFSKVFVREGVVHAVDQLVLVGKPSHASPTDKD--------------------------------NDCVPGSARSRRYRRRSSNANSDGNQSEEPKNPASLTIGANHNSLDTPTASFMLRET-----------------------VSSCAKAFKDKYFPSDGGDVDVGVTDDLLHLKNLCTKLTAGIDDHKVKGKGKSKASGPFLGD----------------------------FSASKEEYLIGVISEILGEISKGDGVSTFEFIGSGVVAALLNYFSCGYFSKEKISELNLPKLRQEGLRRFKAFLEVALPFDGNEGKVPPMTVLIQKLQNALSSLERFPVVLSHPSRSLSGSARLSSGLSALAHPLKLRLCRASGEKTLRDYSSNIVLIDPLASLAAVEEFLWPRVQRSESALKPAAPIG----NTEPGTLPSGAGVSSPSSSTPASTTRRHSSRSRSAINIGDTSKKDPVHEKGTSSSKGKGKGVMKPAQADKGPQTRSNAQKRAVLDKDTQMKPASGDSSSEDEELEISPVDIDDALVIEEDDISDDEDDDNEDVLDDSLPMCTPDKVHDVKLADSVDDDGLATSGRQMNPASGGTSGAAAARASDSIDTGIGNSYGSRGALSFAAAAMAGLGAASGRGIRGSRDLHGRTLNRSSDEPSKLIFTAAGKQLSRHLTIYQAVQRQLMLDEDDDDRFGGSDLVSSDGSRFNDIYTIMYQ--RPDSQVNRLSVGGASS-----------TTPSKSTKSATTNSSVES-------QSHRASLLDSILQGELPCDLEK-SNSTYNVLALLRVLEGLNQLCPRLRAQTLSDRFAEGKITSLDDLSTTAAKVPLDEFVNSKLTPKLARQIQDALALCSGSLPSWCYQLTRACPFLFPFQTRRQYFYSTAFGLSRALNRLQQQQG-----ADGSGSTNEREMRIGRLQRQKVRVSRNRILDSAAKVMEMYSSQKAVLEVEYFGEVGTGLGPTLEFYTLLSHDLQKASLGMWRSSSGDKVSMQIGRDEIEDGKPSAAN---------------------------------------------------RDIVLAPLGLFPRPWPSTADISEGGQFHKVIEYFRLLGRVMAKALQDGRLLDVPLSTAFYKLILGQELDL--HDIVLFDAELGKTLQELRVVVARKHYLEG----VGGDNSSTISDLCLRGCRIEDLSLEFTLPGYPEYILRSG--DEIVDITNLEEYISLVVDATVKRGVTRQIEAFRSGFNQVFDITSLQIFTPSELDYLLCGRR----ELWEVETLAEHIKFDHGYNAKSPAIINLLEIMGELTADQQRAFCQFVTGAPRLPPGGLAVLNPKLTIVRKHSSTSSAAANGAGASETADDDLPSVMTCANYLKLPPYSTKEIMYKKLLYAINEGQGSFDLS", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q54KP2-1", "uniprot_id": "Q54KP2_DICDI", "id": "Q54KP2-1", "name": "HECT-type E3 ubiquitin transferase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSHQKPSEEINSGQTPPTPSTPP-------------------------------------------------------TPPPPTTTTSPPPPPTTTTATTTNNENTSTTSPNNESFENTRQS-----------------------------------------------------LQGLMRNLSGALLDELQSPLR----------------------------------------------------------GGSPAAVGLLNTLIEG---------------------------------------------RNRAKLLLQGLKSE-DETKQMESLLELCDLLSIATEETIAGFPSDSFAPALVNLLNMDHNPDIMLLAGRALCNMIEALPSSVASVINHGAVTILCSKLLSIEYIDLAEQCLQTLEKISQEQPTVVLRAGGLMATLSYIDFFSTGVQRMAITTASNICRQVPQDCFELVRDSIPILTNLLQYSDQKVVELSCLCFSRLIDSFYDSPNKLEVITSKGLMPHLVRIISGMYSS--TTSLSPNTYTQIIRIMAAVCHGCPNITLSLLNEGIISIIQQIMYPSN-----EANPTANRSNQQCFEVLSLINEILPPLPSDFSLLFQQSRNLLTSFGSGRSSSSSS---------------------------------------------SSRRRELEATIAAGAGTTTTTTTTTTTTTSEPTEDPRITIFKEDPELLKSLGQGLFTVLVEMFTSNVNPAVRYKSLGSIIKILYYSPSETVKELLREFAFSSFLASLLGSRDMAIVASALKIVELMMERLPDIFDRFFKREGVVYEVDRLSKLEPQPLELDNNNININNDNNINNNNDNNNNNNNNNNNNNNNNNNNISSINNTTNSTNTSSNSTPTKSTTSNPISIPNSTPIRNSIPPPLASSPFGTNASFFVGSPLNIPNTPTNSNIPTGQSPPNATTTTTPSPSTPFQGSGTITTPAPTSSTTPSTTTRTSLYPSTPEDFKQYVCKEAKKLKDKYFPKLTTMVGATNENFATKELSILKSLSQKLNKCEQEEGIEILEEIKGLLEDTEGISAFEFLQSDLVGSIFHYLTRGDIKK------HAECFAKVFLVTYQKSIVNFNPLKNSSPNPLLLS-------LLIEKLHDALNKVERFNISISDVSGTSSGLKYLTQPFKLKLQKEGTNENIKDYSSNIVLIEPLANITAIEEFLISKVIVTPNLTSTTVPTSTTSLS------------SSSSPPSSSKTGEETKDKEKEKEKEKDTPMLEDEDEDYHDDYDEDDELLNNDANEPEADTVHDVKIDLSTSGQMDKSSPPPNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN---------------------------------------------------NSINTSTTLTTSTSTPTPTTN-STPSTTTTTTTTNNPPITTPPQVPTSIAPVQPKLGIFVDGQRLPSTITIFQAVQKIARAQQQQQQQQQQQQQQQQQQQQQQQQQQQNNNNNNNNTITDEGSLNVPTNRLWDGTHTLKYRYLTAEEMEAPNVQSGSNIYSKPPIKELGTSKLINFLRDDNAFTLTTNDTTTYEIIALLRCLYMFSLDPLPSTTTG---LNPKSVLSSSSPFTSERSLVNLGEFVSQKLTAKIMRQLQDPLALCGGVFPDWCKQLLGSCSFLFPFDCKRLFFYSTSFGIARALSTLQQRQDLIRQTTSTNGSDRGGDFRVGRIQRQKVRIYRNKVLESAIKVMDLYGKSKSILEVEYFGEAGTGLGPTLEFFTLVSKELQRKDLNLWYTDNNDQIPDEDDDKMKIDSTISTTSTIPPISPIISTTTISSTTTTTTTTTPPPPTSLSSNTTTTITTPIIEQLTIIHQYIYSSGGLFPKPINPNITIEK-----KTLEYFKFLGMFIAKAFFDQRLIDLPLSKPMYKYMIDQELNFD--DLRQLAPTYASSLNRLYSLVTSIKQIQARSDLDGAAKKEEVGKLRVDGAVIEDLCLDFTLPGFAGWELKPNGEQINVTLDNIEEYLNLIVKNFLYDGVIRQITSFKEGFNQTFPISSLKPFTISEVESLLCGSLTGSESDWTLDSLMDSTKADHGYTLQSKSVQNIFQIMSEFTPQERKQFLLFISGSPHLPLQGFKGLIPRLTIVKKHHSP----------PLTPDDYLLSVMSCTNYIKLPDYSTREVMKEKLLYAMNEGQSSFHLS", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:.: * . : .. . . :.: . . .. .. . * ::. . .: :. : .. * : . .. : * .: : :*.**:: :* :*::: ::*::* :..*:::. *. .*..*.*: **: : * *** * *** : :.** * * *:. *:. : :* *: :*:***.* :*: :*:.:... *:**.* * *::*** ..** *:: *:* *:.:. * . * :::*:**: * : *.* :* :.:*::*: : * : *: : .:.*:.: :: . ** . : ::*::: . ..* *: .* . :: :: :. . *. :: :*: .* *::* ** :...* . ..* :: ::*** : : *: ** ::: *... ::*:*.* * :::*:: :* ::.:: : .**.:*.:*. :* ::. :*::.*::*::**: *. * ****:: *..* . . .: .: : : .: ....: . :* . : . : * .. . :. . *. . . :.. : : * : . * : *..: . . . ..: : : : .. . . :. *. .: . .:.. : :. .: . . ::: :. . : .: * .. . . . .. .: : * . : . . : : : . : : * : : : . :::: .:::..::: *: . . . :* : : *. :*::***: ::: : . . : . : . .:. . : :. . . . * * . : . .: ::: *** * .. : : .**:..***.* **:**.*.: * :* * :* :*.*:***: :: ** *:*. **:. * : : .. . * . *::*:* : *:.:*..* .**: ...:::**::* .*.******* **::*:*::**: .* :* .. : . * . . : ***. * . * *::** .:***: * **:*:**. .:** :: :* .: *: : . . :: .* :: : :: . : * : *. :*** *:*****:. *: . : * : *:*:*: *:: : ** **: :*:.**:..* : *: * .*:: **** . * .:* : : ****. .* :: :::::..: :::: * *::*:*:** *: * * ****:* .. . ..** * ***:*.**:*** **: ::* .*** * .*** **.**", "identical_positions": 296, "similar_positions": 542, "identity": "12.22%" }, { "cls_id": "homologset.oma.815751", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P33202-1", "uniprot_id": "UFD4_YEAST", "id": "P33202-1", "name": "Ubiquitin fusion degradation protein 4", "aln": "MSENNSHNLDEHESHSENSDYMMDTQVEDDYDEDGHVQGEYSYYPDEDEDEHMLSSVGSFEADDGEDDDNDYHHEDDSGLLYGYHRTQNGSDEDRNEEEDGLERSHDNNEFGSNPLHLPDILETFAQRLEQRRQTSEGLGQHPVGRTLPEILSMIGGRMERSAESSARNERISKLIENTGNASEDPYIAMESLKELSENILMMNQMVVDRIIPMETLIGNIAAILSDKILREELELQMQACRCMYNLFEVCPESISIAVDEHVIPILQGKLVEISYIDLAEQVLETVEYISRVHGRDILKTGQLSIYVQFFDFLTIHAQRKAIAIVSNACSSIRTDDFKTIVEVLPTLKPIFSNATDQPILTRLVNAMYGICGALHGVDKFETLFSLDLIERIVQLVSIQDTPLENKLKCLDILTVLAMSSDVLSRELREKTDI-VDMATRSFQHYSKSPNAGLHETLIYVPNSLLISISRFIVVLFPPEDERILSADKYTGNSDRGVISNQEKFDSLVQCLIPILVEIYTNAADFDVRRYVLIALLRVVSCINNSTAKAINDQLIKLIGSILAQKETASNANGTYSSEAGTLLVGGLSLLDLICKKFSELFFPSIKREGIFDLVKDLS-----------VDFNNIDLKEDGNENISLSDEEGD----------------LHSSIEECDEGDEEYDYEFTDMEIPDSVKPKKISIHIFRTLSL---AYIKNKGVNLVNRVLSQMNVEQEAITEELHQIEGVVSILENPS------TPDKTEEDWKGIWSVLKKCIFHEDFDVSGFEFTSTGLASSITKRITSST-----VSHFILAKSFLEVFEDCIDRFLEILQSALTRLE----------NFSIVDCGLHDGGGVSSLAKEIKIKLVYDGDASKDNIGTDLS-STIVSVHCIASFTSLNEFLRHRMVRMRFLNSLIPNLTSSSTEADREEEENCLDHMRKK-NFDFFYDNEKVDMESTVFGVIFNTFVRRNRDLK--TLWDDTHTIKFCKSLE-GNNRE---SEAAEEANEGKKLRDFYKKREFAQVDTGSSADILTLLDFLHSCG-----------------------------------VKSDSFINSKLSAKLARQLDEPLVVASGALPDWSLFLTRRFPFLFPFDTRMLFLQCTSFGYGRLIQLWKNKSKGSKDLRNDEALQQLGRITRRKLRISRKTIFATGLKILSKYGSSPDVLEIEYQEEAGTGLGPTLEFYSVVSKYFARKSLNMWRCNSYSYRSEMDVDTTDDYITTLLFPEPLNPFSNNEKVIELFGYLGTFVARSLLDNRILDFRFSKVFFELLHRMSTPNVTTVPSDVETCLLMIELVDPLLAKSLKYIVANKD---------DNMTLESLSLTFTVPGNDDIELIPGGCNKSLNSSNVEEYIHGVIDQILGKGIEKQLKAFIEGFSKVFSYERMLILFPDELVDIFGRVEEDWSMATLYTNLNAEHGYTMDSSIIHDFISIISAFGKHERRLFLQFLTGSPKLPIGGFKSLNPKFTVVLKHAEDGLTADEYLPSVMTCANYLKLPKYTSKDIMRSRLCQAIEEGAGAFLLS", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9LYZ7-1", "uniprot_id": "UPL4_ARATH", "id": "Q9LYZ7-1", "name": "E3 ubiquitin-protein ligase UPL4", "aln": "-MENRGQKR---------------MEVVEELPADKRACNSQDFRP---------STSGSSVQAQANDTNPGHENVDAD-----MDTSSSASPSSRSDEEEQEEQDKEDSDYGSCDSDEEDPRQRVLQDYQRQRSSGD------HGKLKSLLLNLTG-----ETDPSGQLSRLTELCEVLS------FSTEESLSSVMANMLSP-------------------VLVKLAKHENNADIMLLAIRAITYLCDVYPPSVEFLVRHDTIPALCQRLLTIEYLDVAEQCLQALEKISRDEPVACLNAGAIMAVLSFIDFFSTSIQRVAISTVVNICKQLSSESPSPFMDAVPILCTLLQYEDRQLVENVAICLTKIADQASESPAMLDQLCRHGLINESTHLLNLNSRTTLSQPVYNGVIGMLRKLSSGSALAFRTLYELNIGYSLKEIMSTYDISHSVSSTHPINACSNQVHEVLKLVIELLPASP---VEDNQLASEKESFLVNQPDLLQQFGRDMLPVMIQVLNSGANVYVS-YGCLSAIHKLTCLSKSGD----------IVELLKNTNMSSVLAGILSRKDHHVIVVALQVAEVLLEKYRDTFLNSFIKEGVFFAIEALLSSDRGQQNQGSADLSQKPVTKEIVKCLCQSFERSLSSSSQTCKIEKDSVYVLATRIKEGFFGPEVFNSEKGLTDVLQNLKNLSVALSELMTVPIDAHVLHDEKFFSIWNQIMERLNGRESVSTFEFIESGVVKSLASYLSNGLYQRKLSKGGPECDSLPFIGKRFEVFTRLLWSDGEATSSLLIQKLQNSLSSLENFPIVLSQFLKQKNSFAAIPNGRCTSYPCLKVRFLKAEGETSLRDYSQDFVTVDPLCYLDAVDQYLWPKVNIEPIDSVEAKDQAIECQSSQLQSTSISCQAESSSPMEIDSESSDASQLQGSQVEDQTQLPGQQNASSSETSSEKEDAVPRLLFRLEGLELDRSLTVYQAILLHKLKSESEATNDSKLSGPHNITYERSAQLGDSRENLFPPGSMEDDEYRPFLSYLFTHRLALRLKGSSHPPYDILFLLKSLEGMNRFLFHLISLERINAFGEGRLENLDDLRVQVRPVPHSEFVSSKLTEKLEQQLRDSFAVSTCGLPPWFNDLMDSCPCLFSFEAKSKYFRLAAFGSQKIRHHPQHLSSSN---VHGEARPVTGSLPRKKFLACRENILESAAKMMELYGNQKVVIEVEYSEEVGTGLGPTLEFYTLVSRAFQNPDLGMWRNDCSFIVGKPVEHSGVLASSSGLFPRPWSGTSTTSDVLQKFVLLGTVVAKALQDGRVLDLPLSKAFYKLILGQELSSFDIHFVDPELCKTLVELQALVRRKKLFAEAHGDSGAAKCDLSFHGTKIEDLCLEFALPGYTDYDLAPYSANDMVNLDNLEEYIKGIVNATVCNGIQKQVEAFRSGFNQVFSIEHLRIFNEEELETMLCGECDLFSMNEVLDHIKFDHGYTSSSPPVEYLLQILHEFDREQQRAFLQFVTGSPRLPHGGLASLSPKLTIVRKHGSD--SSDTDLPSVMTCANYLKLPPYSSKEKMKEKLIYAITEGQGSFHLS", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **..:: :* :: * :. .. .: * *: ** :.:* : .:.: * . . :...* ..*.:**: *:.:::.::** . * : . * :::*.:.: *: . :*.: * .::.*.: .*:::* * . : : ***..: *:* .::. .:: :: : * *.: * :* * *:.: * ...** * :*: *.*:*:*** *:::* *** . *::* : :.*:**:: ** **: * * *..: ::. ..:::.:* * .::. * : . : * .. :: * .**:. .:*:.::. . .: .:: :* *. : :* :: :. : :.: . .:: * . .. : .: :::: *:*.. :. :: :.:.: ::.: : ::.: : ::*::::: ...*:. * * :: :: ::*:.:* * .:* :.: :* * * : ::* .*.: ::: :*: : *: *: :**:* :: * .*:.: :.:: : :. * *.. * : *:* * * :: * :: :.:* .::: : *:.: . .:* ..: *:::.::* .:.. * *: : * *: . * . .* : ..: : *: .. : *. * **: * ..: : ::* :*:*: *. : .: : *: : : * :* ** : .. . * :::*: : . :*..: * : * .*: * *. :* *: . :: .* : : *. . : : ...*.. :: .: * :. ::* . **: .*: :: : : . : ...*.*.: :* : *:.** . .: * :* : : .: .:.:* .*** :* :*:* * ..*:.***: ** :** :.:.*:: .** * * * **.*::: ::: ::** :: : :: *... :.** * :.*:*: .*:.*: :. *::. **.. *:*:**.**.***********::**: * . .*.*** :. .: .: :: ***.* . *....*:: * ***.**::* *.*:**: :**.*::*: . ... * * * ::** : *.* . ... .. .:*.*.* *::** * :* * ..*. :* .*:****:*::: : :**:**::** .**.:*** *:: *: :** :: : :** : ::: :**** .*. :. ::.*: *.:.::* ****:****:** **: **.**:*:* **..* ::* ************** *:**: *:.:* ** ** *:* **", "identical_positions": 342, "similar_positions": 568, "identity": "21.55%" }, { "cls_id": "homologset.oma.815768", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P18395-1", "uniprot_id": "CSDE1_RAT", "id": "P18395-1", "name": "Cold shock domain-containing protein E1", "aln": "--------------------------------------------------------------------------MSFDPNLLHNNGH----------------------------------------------------------------------NGYPNG-----------------TSAALRETGVIEKLLTSYGFIQCSERQARLFFHCSQYNGNLQDLKVGDDVEFEVSSDRRTGKPIAIKLVKIKPEIHP-EERMNGQVVCAVPHNLESKSPAAPGQSPTGSVCYERNGEVFYLTYTSEDVEGNVQLETGDKINFVIDNNKHTGAVSARNIMLLKKKQ-ARYQGVVCAMKEAFGFIERGDVVKEIFFHYSEFKGDLETLQPGDDVEFTIKDRN-------GKEVATDVRLLPQGTVIFEDISIEHFEGTVTKVIP-KVPSKNQNDPLPGRIKVDFVIP--KELPFGDKDTKSKVTLLEGDHVRFNISTDRRDKLERATNIEVLSNTFQFTNEAREMGVIAAMRDGFGFIKCVDRDARMFFHFSEILDGN-QLHIADEVEFTVVPDMLSAQRN---HAIRIKKLPKGTVSFHSHSDHRFLGTVEKEATFSNPKTTSPNKGKDKEAEDGIIAYDDCGVKLTIAFQAKDVEGSTSPQIGDKVEFSISDKQRPGQQIATCVRLL--------------------GRNSNSKRLLG-------------------------------------------------------------YVATLKDNFGFIETANHDKEIFFHYSEFSGDVDSLELGDMVEYSLSKG-----KGNKVSAEKVNKTHSVNGITEEANPTIYSGKVIRPLRGVDPTQIEYQGMIEIVEEG-DMKGEVYPFGIVGMANKGDCLQKGESVKFQLCVLGQNAQTMAYNITPLRRATVECVKDQFGFINYEVGDSKKLFFHVKEVQDG-IELQAGDEVEFSVILNQRTGKCSACNVWRVCEGPKAVAAPRPDRLVNRLKNITLDDASAPRLMVLRQPRGPDNSMGFGAERKIRQAG-VID", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91W50-1", "uniprot_id": "CSDE1_MOUSE", "id": "Q91W50-1", "name": "Cold shock domain-containing protein E1", "aln": "--------------------------------------------------------------------------MSFDPNLLHNNGH----------------------------------------------------------------------NGYPNG-----------------TSAALRETGVIEKLLTSYGFIQCSERQARLFFHCSQYNGNLQDLKVGDDVEFEVSSDRRTGKPIAIKLVKIKPEIHP-EERMNGQVVCAVPHNLESKSPAAPGQSPTGSVCYERNGEVFYLTYTSEDVEGNVQLETGDKINFVIDNNKHTGAVSARNIMLLKKKQ-ARCQGVVCAMKEAFGFIERGDVVKEIFFHYSEFKGDLETLQPGDDVEFTIKDRN-------GKEVATDVRLLPQGTVIFEDISIEHFEGTVTKVIP-KVPSKNQNDPLPGRIKVDFVIP--KELPFGDKDTKSKVTLLEGDHVRFNISTDRRDKLERATNIEVLSNTFQFTNEAREMGVIAAMRDGFGFIKCVDRDARMFFHFSEILDGN-QLHIADEVEFTVVPDMLSAQRN---HAIRIKKLPKGTVSFHSHSDHRFLGTVEKEATFSNPKTTSPNKGKDKEAEDGIIAYDDCGVKLTIAFQAKDVEGSTSPQIGDKVEFSISDKQRPGQQIATCVRLL--------------------GRNSNSKRLLG-------------------------------------------------------------YVATLKDNFGFIETANHDKEIFFHYSEFSGDVDSLELGDMVEYSLSKG-----KGNKVSAEKVNKAHSVNGITEEANPTIYSGKVIRPLRGVDPTQIEYQGMIEIVEEG-DMKGEVYPFGIVGMANKGDCLQKGESVKFQLCVLGQNAQTMAYNITPLRRATVECVKDQFGFINYEVGDSKKLFFHVKEVQDG-VELQAGDEVEFSVILNQRTGKCSACNVWRVCEGPKAVAAPRPDRLVNRLKNITLDDASAPRLMVLRQPRGPDNSMGFGAERKIRQAG-VID", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A3Q1ML77-1", "uniprot_id": "A0A3Q1ML77_BOVIN", "id": "A0A3Q1ML77-1", "name": "Cold shock domain-containing protein E1", "aln": "----------------------------MENVFTVSSDPHPPPAAPPSLSLPLSSSSTSSGTKKQKRTPTYQRSMSFDPNLLHNNGH----------------------------------------------------------------------NGYPNG-----------------TSAALRETGVIEKLLTSYGFIQCSERQARLFFHCSQYNGNLQDLKVGDDVEFEVSSDRRTGKPIAVKLVKIKQEILP-EERINGQVVCAVPHNLESKSPAAPGQSPTGSVCYERNGEVFYLTYTPEDVEGNVQLETGDKINFVIDNNKHTGAVSARNIMLLKKKQ-ARYQGVVCAMKEAFGFIERGDIVKEIFFHYSEFKGDLESLQPGDDVEFTIKDRN-------GKEVATDVRLLPQGTVIFEDISIEHFEGTVTKVIP-KVPSKNQNDPLPGRIKVDFVIP--KELPFGDKDTKSKVTLLEGDHVRFNISTDRRDKLERATNIEVLSNTFQFTNEAREMGVIAAMRDGFGFIKCVDRDARMFFHFSEILDGN-QLHIADEVEFTVVPDMLSAQRN---HAIRIKKLPKGTVSFHSHSDHRFLGTVEKEATFSNPKTTSPNKGKEKETEDGIIAYDDCGVKLTIAFQAKDVEGSTSPQIGDKVEFSISDKQRPGQQIATCVRLL--------------------GRNSNSKRLLG-------------------------------------------------------------YVATLKDNFGFIETANHDKEIFFHYSEFSGDVDSLELGDMVEYSLSKG-----KGNKVSAEKVNKTHSVNGITEEADPTIYSGKVIRPLRSVDPTQNEYQGMIEIVDEG-DMKGEVYPFGIVGMANKGDCLQKGESVKFQLCVLGQNAQTMAYNITPLRRATVECVKDQFGFINYEVGDSKKLFFHVKEVQDG-IELQAGDEVEFSVILNQRTGKCSACNVWRVCEGPKAVAAPRPDRLVNRLKNITLDDASAPRLMVLRQPRGPDNSMGFGAERKIRQAG-VID", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A287B2T9-1", "uniprot_id": "A0A287B2T9_PIG", "id": "A0A287B2T9-1", "name": "Cold shock domain-containing protein E1", "aln": "----------------------------MENVFTVSSDPHPPPATPPSLSLPLSSSSTSSGTKKQKRTPTYQRSMSFDPNLLHNNGH----------------------------------------------------------------------NGYPNG-----------------TSAALRETGVIEKLLTSYGFIQCSERQARLFFHCSQYNGNLQDLKVGDDVEFEVSSDRRTGKPIAVKLVKIKQEILP-EERINGQVVCAVPHNLESKSPAAPGQSPTGSVCYERNGEVFYLTYTPEDVEGNVQLETGDKINFVIDNNKHTGAVSARNIMLLKKKQ-ARCQGVVCAMKEAFGFIERGDVVKEIFFHYSEFKGDLETLQPGDDVEFTIKDRN-------GKEVATDVRLLPQGTVIFEDISIEHFEGTVTKVIP-KVPSKNQNDPLPGRIKVDFVIP--KELPFGDKDTKSKVTLLEGDHVRFNISTDRRDKLERATNIEVLSNTFQFTNEAREMGVIAAMRDGFGFIKCVDRDARMFFHFSEILDGN-QLHIADEVEFTVVPDMLSAQRN---HAIRIKKLPKGTVSFHSHSDHRFLGTVEKEATFSNPKTTSPNKGKEKEAEDGVIAYDDCGVKLTIAFQAKDVEGSTSPQIGDKVEFSISDKQRPGQQIATCVRLL--------------------GRNSNSKRLLG-------------------------------------------------------------YVATLKDNFGFIETANHDKEIFFHYSEFSGDVDSLELGDMVEYSLSKG-----KGNKVSAEKVSKTHSVNGITEEADPTIYSGKVIRPLRSVDPTQTEYQGMIEIVEEG-DMKGEVYPFGIVGMANKGDCLQKGESVKFQLCVLGQNAQTMAYNITPLRRATVECVKDQFGFINYEVGDSKKLFFHVKEVQDG-IELQAGDEVEFSVILNQRTGKCSACNVWRVCEGPKAVAAPRPDRLVNRLKNITLDDASAPRLMVLRQPRGPDNSMGFGAERKIRQAG-VID", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "O75534-1", "uniprot_id": "CSDE1_HUMAN", "id": "O75534-1", "name": "Cold shock domain-containing protein E1", "aln": "--------------------------------------------------------------------------MSFDPNLLHNNGH----------------------------------------------------------------------NGYPNG-----------------TSAALRETGVIEKLLTSYGFIQCSERQARLFFHCSQYNGNLQDLKVGDDVEFEVSSDRRTGKPIAVKLVKIKQEILP-EERMNGQVVCAVPHNLESKSPAAPGQSPTGSVCYERNGEVFYLTYTPEDVEGNVQLETGDKINFVIDNNKHTGAVSARNIMLLKKKQ-ARCQGVVCAMKEAFGFIERGDVVKEIFFHYSEFKGDLETLQPGDDVEFTIKDRN-------GKEVATDVRLLPQGTVIFEDISIEHFEGTVTKVIP-KVPSKNQNDPLPGRIKVDFVIP--KELPFGDKDTKSKVTLLEGDHVRFNISTDRRDKLERATNIEVLSNTFQFTNEAREMGVIAAMRDGFGFIKCVDRDVRMFFHFSEILDGN-QLHIADEVEFTVVPDMLSAQRN---HAIRIKKLPKGTVSFHSHSDHRFLGTVEKEATFSNPKTTSPNKGKEKEAEDGIIAYDDCGVKLTIAFQAKDVEGSTSPQIGDKVEFSISDKQRPGQQVATCVRLL--------------------GRNSNSKRLLG-------------------------------------------------------------YVATLKDNFGFIETANHDKEIFFHYSEFSGDVDSLELGDMVEYSLSKG-----KGNKVSAEKVNKTHSVNGITEEADPTIYSGKVIRPLRSVDPTQTEYQGMIEIVEEG-DMKGEVYPFGIVGMANKGDCLQKGESVKFQLCVLGQNAQTMAYNITPLRRATVECVKDQFGFINYEVGDSKKLFFHVKEVQDG-IELQAGDEVEFSVILNQRTGKCSACNVWRVCEGPKAVAAPRPDRLVNRLKNITLDDASAPRLMVLRQPRGPDNSMGFGAERKIRQAG-VID", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0ZY56-1", "uniprot_id": "A0A8V0ZY56_CHICK", "id": "A0A8V0ZY56-1", "name": "Cold shock domain-containing protein E1", "aln": "--------------------------------------------------------------------------MSFDPNLLHNNGH----------------------------------------------------------------------NGYPNG-----------------TSATLRETGVIEKLLTSYGFIQCSERQARLFFHCSQYNGNLQELKVGDDVEFEVSSDRRTGKPIAVKLVKIKPEILP-EERINGQVVCAVPHNLESKSPAAPGQSPTGSVCYERNGEVFYLTYTPEDVEGNIQLETGDKINFVIDTNKHTGAVSARNIMLLKKKQ-ARCQGVVCAMKEAFGFIERGDVVKEIFFHYSEFKGDLETLQPGDDVEFTIKDRN-------GKEVATDVRLLPQGTVIFEDISIEHFEGTVTKVIP-KVPSKNQNDPLPGRIKVDFVIP--KELPFGDKDTKSKVTLLESDHVRFNISTDRRDKLERATNIEVLPNTFQFTNETREMGVIAAMRDGFGFIKCVDRDARMFFHFSEIMDGN-QLHISDEVEFTVVPDMLSAQRN---HAIRIKKLPKGTVSFHTQSDHRFVGTIDKEATP--AKATSPNKGKEKEAEDGIIVYDDCGVKLTIPYQAKDVEGSANPQIGDKVEFSVCEVKRTGLQTAVSVRML--------------------GRNYSSKRLLG-------------------------------------------------------------YVAALKDNFGFIETANHDKEIFFHYSEYCGDIDSLELGDTVEYSLSKG-----KGNKVSAEKVNKTHAVNGITEEADPTVYSGKVIRPLRSVDPTQTEYQGMIEVMEDG-EMKGEFYPFGIVGMANKGDCLQKGETVKFQLCVLGQNGQTMAVNITPFRRATVECVKDQFGFINYEVGDSKKLFFHVKEVQDG-VELQAGDEVEFSVILNQRTGKCSACNVWRVCEGAKAVAAPRPDRLVNRLKNINLDDANAPRLTVLRQPRGPDNSKGFGAERKIRQAG-VID", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "B7Z0E2-1", "uniprot_id": "UNR_DROME", "id": "B7Z0E2-1", "name": "RNA-binding protein Unr", "aln": "MNTQSKVYRTGEEIYDNLPCDSYFNMNAIRNLGIPTTFPTIGTFTLDSTTLGLQPQGQGPSPQQQQHQQQQQQQQQQHQQNMHHHQHQQQHMQQQQQQQQHQQQHQQQQHQQQQQHQQQQQQQQQHPTIGMFDANEVNDVIQNPPQIGVFQSNSVLTNGAGSGSSIFGSQSSNSSAAAADPSQTTRETGIIEKLLHSYGFIQCCERQARLFFHFSQFSGNIDHLKIGDPVEFEMTYDRRTGKPIASQVSKIAPEVVLSEERVTGTVTTELRT--DSANNVLNSSETTGRISYENRGECFFLPYTKDDVEGNVNLRAGDKVSFQIATN-QRGNLGACHIRLENPAQPVKYRGVVCSMKESFGFIERADVVKEIFFHFSEAEGNVE-LRPGDDVEFTIQTRSSASVPPQGREFACNITRLAPGSVIFEDVDSTVYKGQVLKSLDRNNPVRQNNDPLPGRIRYRALDYSEVEVPFGDKDQKGDFTLRHGDWVQFLLATDRRDQLQRATSIALLDETFKVSGEKREQGTIASLKEGFGFLRCVERQARLFFHFTEVLDTSREIDINDEVEFTVIQEPGLAYNNSRLQAIRIKHLPPNSVQFETLVASNIEGCVTREAPK------SPIKSQDR-VEGGVITYEHADVKKTIMYFLKDCE--KPPRIGERVRFDIYMVKRNKECIAVNVQQVSLHQQQQQQQQQLHLNQSNAGANINQNDQLGGLSNGISSSSSNASLQNGYVMHGSPGGSTSSVGSNNPVHLDEFKMENNNHAGSDAGQVYRGFIAVMKENFGFIETLSHDEEVFFHFSNYMGNPNWLELGQEVEYTLARNGNTSVSGNCLPAENVRMLPKNSIPQPAVLETTHNGVVARPLRCINPDQQEYAGLIEILDELRTTVISQHEFGITSLVNKRDLLQKGDLVSFRIDESGRAACVNAVRQK--KRATVDSIKGQFGFLNFEVEDGKKLFFHMSEVQGNTVALHPGDTVEFSVVTNQRNGKSSACNVLKIND--------RPDRLISRLK--LNGDDTVPRLILIRAPKGPQGKGFSVLARHPRIPGNLVE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : :*:: * ** .* .* : ****:***** *******.********* **:.**::.**:** ****:: ********* :: ** *: ***:.* *. : :* . . ....** :.**..** *:*.** :*****::*.:***:.* * .* : * :.* :* * : * .: :****:***:******.*:*******:** :*::* *:*********: *. *:*.* :: *. *:*****:. ::* * * : : * :::********: : *:****** *...** ..* *:* ::*****:*:***.* :* :**:.:.* ** *.**::::****::**:*:.*:****:*::* . ::.* *******: : * .* :*****:** .:*.*.: .: * : :**. ** *.::: .*.*:*.*:...** ** : ** * *:**::*.*.: :* *. *: : * * ..: ** ::*.:*:******* .**:*:***:*:: *: : ****: ***:*::. .** :.**:* . . * :.* * **** ::* * ** *:**:::: . : ***..:.** * ****: *.*:: *: . . * . . :****:.:*.****:*:** *.******:.***.. : *:.** *****: ***.**.***** :: : *****:.*** .* ..*** ::* *:**:.. *: * .* :::", "identical_positions": 357, "similar_positions": 245, "identity": "33.55%" }, { "cls_id": "homologset.oma.815784", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q921G8-1", "uniprot_id": "GCP2_MOUSE", "id": "Q921G8-1", "name": "Gamma-tubulin complex component 2", "aln": "MSEFRIHHDVNELLSLLRIHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTPEDFLKKYDELKSKNTRNLDPLVYLLSKLTEDKETLQFLQQNAKERAELAASAATSNTTSFSIPVAASKMSTQELEELRKQLGSVSTGSTLQQSLELTRKMLRDKQNKKNSGQPLPVFPAWVYERPTLAGDFLIGSGLSSDTVLPIGTLPLASQESAVVEDLLYVLVGVDGRYITAQP-----LAGRQ-NRTFLVDPNLDLSIRELVNRILPVAASYSTVTRFIEEKSSFEYGQVNHALAAAMR----TLVKEYLILVTQLEQLHRQGLLSLQKLWFYIQPAMRTIDILASLATSVDKGEC---VGGSTLSLLHDRSFNYTGDSQAQELCLYLTKAASAPYFEILEKWIYRGIIHDPYSEFMVEEH-ELRKEKIQED----YNDKYWDQRYTVLPQQIPSFLQKVAGKILSTGKYLNVVRECGHDVTCP-------VAKEIIYTLK--ERAYVEQIEKAFNYASKVLLDFLMEEKELVAHLRSIKRYFLMDQ-GDFFVHFMDLTEEELRKPVEDIILTRLEALLE--LALRMSTANTDPFKDDLKIELMPHDLITQLLRVLAIETKQEKAMTHADPTELTLSG-----------------------------------LEAFSFDYMVKWPLSLIINRKALTRYQMLFRHMFYCKHVERQLCSVWISNKTAKQHALH------SAKWFAGAFTLRQRMLNFVQNIQYYMMFEVMEPTWHILEKNLKSASNIDDVLGHHTSFLDNCLKDCMLTNP-ELLKVFSKLMSVCVMFTNCMQKFTQS-MKLDSELGRLTLDQGSVQGPPTETERIEDRPRKELTRKHLSEHVDAPQLASGFEATINNFDKNFSAHLLDLLARLSVYSTSDCEHGMASVISRLDFNGFYAERLERLSAERSQKAAPQVPVPRGPSAPAPRVAIPAQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8C2LCP4-1", "uniprot_id": "A0A8C2LCP4_CRIGR", "id": "A0A8C2LCP4-1", "name": "Gamma-tubulin complex component", "aln": "MSEFRIHHDVNELLSLLRTHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTPEEFLKKYEELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAKERAELAANAASSSTTSFNIPVATSKMSTQELEELRKQLGSVATGSTLQQSLELTRKMLRDKQNKKNSGQPLPVFPAWVYERPTLAGDFLIGSGLSSDTALPIGTLPLTSQESAVVEDLLYVLVGVDGRYITAQP-----LAGRQ-NRTFLVDPNLDLSIRELVNRILPVAASYSTVTRFIEEKSSFEYGQVNHALAAAMK----TLVKEYLILVTQLEQLHRQGLLSLQKLWFYIQPAMRTIDILASLATSVDKGEC---VGGSTLSLLHDRSFNYTGDSQAQELCLYLTKAASAPYFEILEKWIYRGIIHDPYSEFMVEEH-ELRKEKIQED----YNDKYWDQRYTVLPQQIPSFLQKVAGKILSTGKYLNVVRECGHDVTCP-------VAKEIIYTLK--ERAYVEQIEKAFNYASKVLLDFLMEEKELVAHLRSIKRYFLMDQ-GDFFVHFMDLTEEELRKPVEDITPTRLEALLE--LALRMSTANTDPFKDDLKIDLMPHDLITQLLRVLAIETKQEKAMTHADPTELTLSG-----------------------------------LEAFSFDYMVKWPLSLIINRKALTRYQMLFRHMFYCKHVERQLCSVWISNKTAKQHALH------SAKWFAGAFTLRQRMLNFVQNIQYYMMFEVMEPTWHILEKNLKSASNIDDVLGHHTSFLDNCLKDCMLTNP-ELLKVFSKLMSVCVMFTNCMQKFTQS-MKLDSELGRLTLEQGSVQGQPTETERIEDRPRKEPTRKHLSEYVDTPQLASGFEATINNFDKNFSAHLLDLLARLSVYSTSDCEHGMASVISRLDFNGFYAERLERLSAERSQKAAPQVPVPRGPPAPTPRVAIPAQ", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q9BSJ2-1", "uniprot_id": "GCP2_HUMAN", "id": "Q9BSJ2-1", "name": "Gamma-tubulin complex component 2", "aln": "MSEFRIHHDVNELLSLLRVHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTPEDFLKKYDELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAKERAELAAAAVGSSTTSINVPAAASKISMQELEELRKQLGSVATGSTLQQSLELKRKMLRDKQNKKNSGQHLPIFPAWVYERPALIGDFLIGAGISTDTALPIGTLPLASQESAVVEDLLYVLVGVDGRYVSAQP-----LAGRQ-SRTFLVDPNLDLSIRELVHRILPVAASYSAVTRFIEEKSSFEYGQVNHALAAAMR----TLVKEHLILVSQLEQLHRQGLLSLQKLWFYIQPAMRTMDILASLATSVDKGEC---LGGSTLSLLHDRSFSYTGDSQAQELCLYLTKAASAPYFEVLEKWIYRGIIHDPYSEFMVEEH-ELRKERIQED----YNDKYWDQRYTIVQQQIPSFLQKMADKILSTGKYLNVVRECGHDVTCP-------VAKEIIYTLK--ERAYVEQIEKAFNYASKVLLDFLMEEKELVAHLRSIKRYFLMDQ-GDFFVHFMDLAEEELRKPVEDITPPRLEALLE--LALRMSTANTDPFKDDLKIDLMPHDLITQLLRVLAIETKQEKAMAHADPTELALSG-----------------------------------LEAFSFDYIVKWPLSLIINRKALTRYQMLFRHMFYCKHVERQLCSVWISNKTAKQHSLH------SAQWFAGAFTLRQRMLNFVQNIQYYMMFEVMEPTWHILEKNLKSASNIDDVLGHHTGFLDTCLKDCMLTNP-ELLKVFSKLMSVCVMFTNCMQKFTQS-MKLDGELGGQTLEHSTVLGLPAG---AEERARKELARKHLAEHADTVQLVSGFEATINKFDKNFSAHLLDLLARLSIYSTSDCEHGMASVISRLDFNGFYTERLERLSAERSQKATPQVPVLRGPPAPAPRVAVTAQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9C5H9-1", "uniprot_id": "GACP2_ARATH", "id": "Q9C5H9-1", "name": "Gamma-tubulin complex component 2", "aln": "-----------------------------------------------------------------------------------------------------------------MESMTPISCPTTP----------RWNQDRPFLTG-RFHQETRASSKFADSKRFTLDSS--------------------------SSGVEQAIGCYDTPVQELIVIDDLLSALVGIEGRYISIKR-----FHGKEDSIAFQVDPSMDLALQELAKRIFPLCEYYLLIDQFVESSSQFKNGLVNHAFAAALR----ALLLDYQAMVAQLEHQFRLGRLSIQGLWFYCQPMMGSMRALAAVIQQASTKQF---VGSGVLNLLQSQAKAMAGDNSVRSLLEKMTECASNAYLSILERWVYEGIIDDPYGEFFIAENRSLKKESLSQD----STAKYWSQRYS-LKDTIPGFLANIAATILTTGKYLNVMRECGHNVQVP-------ISERSKLTIFGSNHHYLECIKAAHEFASIELVNLIKDKYDLVGRLRSIKHYLLLDQ-GDFLVHFMDIAREELNKKVHEISVEKLQSLLD--LALRTTAAAADPRHEDLTCCVDRASLLTTLG-----MHKDTDSNSIEDP--MSITG-----------------------------------LETFSLSYKVQWPLSIVISKKALSKYQLIFRFLFHCKHVERQLCGAWQIHQGIRSMNSK------GTAILRSSLLCRS-MLKFISSLLHYLTFEVLEPNWHVMHDRLQSTRSVDEVIQHHDFFLDKCLRGCLLLLP-DVLKKMEKLKSVCLQYAAATQWLISSSIDINSQS----------------------HPQKTMIR-------DTTVTES-----IFNFEREFNSELQSLGPVLSKG--SQAEP--------------YLTHLSQWILGVSKE-----------------------", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q9XYP7-1", "uniprot_id": "GCP2_DROME", "id": "Q9XYP7-1", "name": "Gamma-tubulin complex component 2 homolog", "aln": "MYALLVFVERYSECKPVSESSSSTSLSAMGLPHGNKTSDVNSAAGSVPTTLAIASTSTILTTSQNVSGSTRLSLTQSQD-------------FPTSTPVNCKKATESDTTPVVFVRRGPMDRNRGAGKDERNDLSVIKERVLNAVSDQSLSGYRSVTNKTGNSPKSMPNDLVTLTDVPDEYRTHLLWEYYKVDG---DKVPRAEIAAMPLLSQESMLLDELLHCLTGIRESLLVPQKPIISAVGLAKYDTDFDIHTHLDRSLTHQVREILPLASYFMGVQKIIAATD--GLGQVMNSLNEALQ----ELTHDFYLIIVQAEQELRHNRLTLQKLLYYLQPTMWVMHEVWSSLVIIQLSDS---RDAEVLTYLHERIKRLEGNKDAQQLIIGLVRKAAKPYMRMLQMWIQKGVIVDRHREFLVVDNEVIHRDELPEH----YSDDYWERRYTLRDEQIPSFLAKYSDKILRTGKYLNVIRQCGKRVMPT-------QEMNLEFDPT--SERHVSVINDAYYFAARMLLDVLLTENDLMGHLQSVKRYLLLNQ-GDFTMQFMDACEDELTKNVDHVLPMTLENLLG--LTLRISSARNDPYKDDLHCELLPYDLVTQMS------KIMKKEENWQAQPRLDLSG-----------------------------------LECFAFTYEVKWPCSLVLNHISISKYQMLFRQLFYCKHVERQLCKIWKENSIARQFEPQ------AASLYRAAFTLRQRMMNAIQNLEYYMMIEIIEPNWHIFIEKMKTVENVDNVLRLHQDFLDSCLKNCMLTESSHLNRSIFKLCKICLKYCEFIQITQRYFQDAELRSMVRDS---------------ADSSESEQESLHCPQIETPLDPTDTFSERVRRFDLEFTQLLISFLKQINSMAKKNTADCFMNLVHRINFNAFYTDQMDKMCVEDAIG-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38863-1", "uniprot_id": "SPC97_YEAST", "id": "P38863-1", "name": "Spindle pole body component SPC97", "aln": "------------------------------------------------------------------------------------------------MEIKEVDDRAELLRYTNNIPLLGKLVNHQPLWSTNPKLKSFSLEKISAPDQRRVQEALVVKDLLNVLIGLEGTYIRYFNDYE-------------------PSDPETPI-EFKIAKKMDPSFKTFSRRIVRYGKQYMILTR----AYEKWSDTSFGMVLQRFAYEIRRFLEDVY-LKTLVERLERDFNKVPNFSIRELEQIINETEVNKQMELLYNIYEEIFREIEERRTNQSSQEDFNNFMDSMKNESSLHLRLMVAFDTTVYPVPKGGAILKIFQQKILENLGDRSSVMFLKKLLNNISQDYCTMLYEWLTQGILNDPYQEFMTYDDLEGKTDNIFDTRDRAWDTQYFIRKDVLLRDCDSEEDKNLLFKMLRTGILLKVVRASLQIPTIPSNSSDITIQEINDFADLMEGSNLELYVDKCYSRANEIFLKLFFQGYDLINVLKHLQQIFLGYQSGHNVLKFLTKNMGELTKHYRNDNNANYDKLLQNFELERQSENPNNLMRQLLMIQFDTETLPQVLSHYLQIYPEVPENNSANDDSDPLMHANNFKNMNAILFDELSKERTGAYHGSNLELYTPKSAIYHLKFDINIPYPLNIIISRTCMIKYQIILRYQLVLQYHSRLLDETWMDLNKTPSWKYRGYSHTVKRRIVRATRVLHAKMNHFIKTIMEYFNQNVIDKEVYSLEKCYRNPTLAVAIQNELEGGLTNIMTNRCLSDLIPLQLQIFDIVYKFCKFIKSMRAKLCQLDPVLYEKHKSGMMKTLNEG---------YRTNNGGQEDVGYQEDAALELIQKLIEYISNASSIFRKCLINFTQELSTEKFDFYDSSSVDAAG--IERVLYSIVPPRSASASSQR-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . * : .. : :. : . : : : . . : : : : . : : : : * : : : . * . : : : : :. . .. *. ::.: *: . : : . : * :* *: .*:: * : **: :. : : : : .*: :: : . : .:* ** *:*:* . : . :. .. * ::..: :*: *: ::: :* * *. ::*: ** * . : ** * : : :: * . * : . : . : : : : :* .:::.: .: :**:::* : :: .* * * . . : .: : * : :..: *: :::: : : . :. : * . : . * : : .: : : . ... . . : . . * * .: :. . * : : ", "identical_positions": 48, "similar_positions": 178, "identity": "4.91%" }, { "cls_id": "homologset.oma.815785", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GK03-1", "uniprot_id": "A0A8I6GK03_RAT", "id": "A0A8I6GK03-1", "name": "Gamma-tubulin complex component", "aln": "MIHELLLALSGYPGSIFTWNKRSG------------------LQVSQDFPFLHPSETSVLNRLCRLGTDYIRFTEFIEQY----------TGHVQQQDHHPSQQGQGGLHGIYLRAFCTGLDSVLQPYRQALLDLEQEFLADPHLSISHVNYSLDQFQLLFPSVMVVVEQIKSQKIHGCQILETVYKHSCGGLPPVRSALEKILAVCHGVMYKQLSAWMLHGLLLDQHEEFFIKQGPSSGNVSAQMEEDEEDLGIGGLTGKQLRELQDLRLIEEENMLAPSLKQFSLRVEILPSYIPVRVAEKILFVGESVQMFENQ-------------------------------------NVNLTRKGSILKNQEDTFAAELHRLKQQPLFSLVDFEQVVDGIRSTVAEHLWKLMVEESDLLGQLKIIKDFYLLGRGELFQAFIDTAQHMLKTPPTAVT-EHDVNVAFQQSAHKVLLDDDNLLPLLHLTIEYHGKDHKADATQPR----EVPSRETSPREPPSSGWAALGLSYKVQWPLHILFTPAVLEKYNVVFKYLLSVRRVQAELQHCWALQMQRKHLKSNQTD----------------AVKWRLRNHMAFLVDNLQYYLQVDVLESQFSQLLHQINSTRDFESIRLAHDHFLSNLLAQSFILLK--------------PVFHCLNEILDLCHSFCSLVSQNLGPLDERGAAQLSILVKGFSRQSSLLFKILSS--VRNHQINSDLAQLLLRLDYNKYYTQAG-GTLGSFGM------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D4F8-1", "uniprot_id": "GCP4_MOUSE", "id": "Q9D4F8-1", "name": "Gamma-tubulin complex component 4", "aln": "MIHELLLALSGYPGSIFTWNKRSG------------------LQVSQDFPFLHPSETSVLNRLCRLGTDYIRFTEFIEQY----------TGHVQQQDHHPPQQGQGGLHGIYLRAFCTGLDSVLQPYRQALLDLEQEFLADPHLSISHVNYSLDQFQLLFPSVMVVVEQIKSQKIHGCQILETVYKHSCGGLPPVRSALEKILAVCHGVMYKQLSAWMLHGLLLDQHEEFFIKQGPSSGTLSAQLEEDEEDLGIGGLTGKQLRELQDLRLIEEENMLAPSLKQFSLRVEILPSYIPVRVAEKILFVGESVQMFENQ-------------------------------------NVNLTRKGSILKNQEDTFAAELHRLKQQPLFSLVDFEQVVDRIRSTVAEHLWKLMVEESDLLGQLKIIKDFYLLGRGELFQAFIDTAQHMLKTPPTAVT-EHDVNVAFQQSAHKVLLDDDNLLPLLHLTIEYHGKDHKADATQPR----EVPSRETSPREAPSSGWAALGLSYKVQWPLHILFTPAVLEKYNVVFKYLLSVRRVQAELQHCWALQMQRKHLKSNQTD----------------AVKWRLRNHMAFLVDNLQYYLQVDVLESQFSQLLHQINSTRDFESIRLAHDHFLSNLLAQSFILLK--------------PVFHCLNEILDLCHSFCSLVSQNLGPLDERGAAQLSILVKGFSRQSSLLFKILSS--VRNHQINSDLAQLLLRLDYNKYYTQAG-GTLGSFGM------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGJ1-1", "uniprot_id": "GCP4_HUMAN", "id": "Q9UGJ1-1", "name": "Gamma-tubulin complex component 4", "aln": "MIHELLLALSGYPGSIFTWNKRSG------------------LQVSQDFPFLHPSETSVLNRLCRLGTDYIRFTEFIEQY----------TGHVQQQDHHPSQQGQGGLHGIYLRAFCTGLDSVLQPYRQALLDLEQEFLGDPHLSISHVNYFLDQFQLLFPSVMVVVEQIKSQKIHGCQILETVYKHSCGGLPPVRSALEKILAVCHGVMYKQLSAWMLHGLLLDQHEEFFIKQGPSSGNVSAQPEEDEEDLGIGGLTGKQLRELQDLRLIEEENMLAPSLKQFSLRVEILPSYIPVRVAEKILFVGESVQMFENQ-------------------------------------NVNLTRKGSILKNQEDTFAAELHRLKQQPLFSLVDFEQVVDRIRSTVAEHLWKLMVEESDLLGQLKIIKDFYLLGRGELFQAFIDTAQHMLKTPPTAVT-EHDVNVAFQQSAHKVLLDDDNLLPLLHLTIEYHGKEHKADATQAR----EGPSRETSPREAPASGWAALGLSYKVQWPLHILFTPAVLEKYNVVFKYLLSVRRVQAELQHCWALQMQRKHLKSNQTD----------------AIKWRLRNHMAFLVDNLQYYLQVDVLESQFSQLLHQINSTRDFESIRLAHDHFLSNLLAQSFILLK--------------PVFHCLNEILDLCHSFCSLVSQNLGPLDERGAAQLSILVKGFSRQSSLLFKILSS--VRNHQINSDLAQLLLRLDYNKYYTQAG-GTLGSFGM------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9M350-1", "uniprot_id": "GACP4_ARATH", "id": "Q9M350-1", "name": "Gamma-tubulin complex component 4", "aln": "MLHELLLALLGFTGDLIVDEREQRKTLGLAFNSDSPLSDECTFKLAPDISFIEPSERDLIERLIKLGFYYRELDRFAKKSRNLSWIRSVTSVHPLERADELSKQSREKKPSVYRRAIANGIGEILSVYRSAVLHIEQKLLAETTPILATVTEGLNKFFVLFPPLYEVILEIERDDIRGGQLLNVLNKRCHCGVPELRTCLQRLLWNGHQVMYNQLAAWMVYGILQDPHGEFFIKR-QDDGDLDHRSSQEEVSEKLARTS-------------VHETSLTDWHSGFHISLDMLPDYIPMRLGESILFAGKAIRVLRNPSPAFQFQKDKSFQQTMRGSQRIRGFMHSDFPETETELDADLTGGELLPQSEADKIEAMLKDLKESSEFHKRSFECTVDSVRAIAASHLWQLVVVRADLNGHLKALKDYFLLEKGDFFQCFLEESRQLMRLPPRQSTGESDLMVPFQLAATKTIAEEDKYFSRVSLRMPSFGVTVRSSQADMVRSKVSLTGKANLTSDTSVDGWDAIALEYSVDWPMQLFFTQEVLSKYLKVFQYLIRLKRTQMELEKSWASVMHQDHIESAQHRKDGLNGSTSQQRRQGIRPMWRVREHMAFLIRNLQFYIQVDVIESQWKVLQTHIHDSQDFTELVGFHQEYLSALISQSFLDIG--------------SVSRILDSIMKLCLQFCWNIENQE---SNPNTSELENIAEEFNKKSNSLYTILRSSKLAGSQRAPFLRRFLLRLNFNSFYEATARGVLNVVRQRPALPL", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q9VKU7-1", "uniprot_id": "GCP4_DROME", "id": "Q9VKU7-1", "name": "Gamma-tubulin complex component 4 homolog", "aln": "MIHDLLLACRSHNPEQLG-IKAFN-------------------ETTVIDQFIHPCEREIFMDIIKIIKVYQEVEQFTHSS---------------GRKSDTHGELPDSLHGYYLLNLAKGIEMALEEYYAEIGRLEKYCLGNERNSLSYVYNALYAKFPLLVFMRNLITEIHVLNLRGCVLLHNLHQQCEHGDIQLEKAIKIIMKPVKNAFFSSLAHWLLFGVIDDVHSEFFIKFTPTDAVDGSSFSKSATCS-----------------LLSAEKNPEDYIWQYEVNMSQLPGFFSIVLAEKVLFVGQTVLVFKMG--------------------RNVKVKNKTDPLAAKLAELDSDDIYQLWSGRESEFFKMVVDLSNEDTINVFRLEKVIIDIKNYVSARLSEIAVNEVDLERQMGLIKDFFLLGRGEFYLEFCSQMVGTMETYREERF--KNVTRSFELAATVTGITDD---------LDKFSLICQRSTSEPD-------------DTSDFNFLQGLSLKYEYEWPLNLLFSPTTIERYNNIFRFLLIIRTYQYEIQRVWAKQTWRAKSAKDVPPN---------------NKIITLRNYLMFFLNNMQYYIQVDVLESQFGILMNVIKSRSDFEVIQRAHTVFLANVLSHCFLLNESETQLNVTGSQNRNPIYGTLLKLFGICEKFAHMTQTKDP--SDDLEDEVDQLNESFGVQIASLIQLLVD--VKSASCLGPLSQLLLRLDFNCWFSASHNTSA-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*:**** .. . : : : : *:.*.* .:: : :: * .. .* .. : . : . * :..*: *. * : :*: *.: :: * * *: : :: :*. .::* :*. : ::. * :...:: :: : .::..*: *::.*:: * * ***** .. . .:. *. : : :. **.::.: :.*.:**.*::: ::. : : : ... . : : *.:. : :* .: :: .: :* :: * . ** :: :**::** :*::: * . :. :: .*: :* . :* : .. : . :: . . .:.*.*. :**::::*: .:.:* :*::*: :: * *::: ** : : . :*::: *:: *:*:*:****:***: * *:. ** : * :*: ::::.*: .: * .:: :* .*. . : .: ::. : : *. : * :* . : . . * ::****::* :: : ", "identical_positions": 99, "similar_positions": 233, "identity": "12.76%" }, { "cls_id": "homologset.oma.815786", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JUU7-1", "uniprot_id": "A0A0G2JUU7_RAT", "id": "A0A0G2JUU7-1", "name": "", "aln": "MATPDQKSPNVLLQNLCCRILGRS---------EADVAQQFQFAVRVIGSNFAPTVERDEFLVAEKIKKELIRQRREADAALFSELHRKLHSQG---VLKNKWSILYLLLNLSEDPRKQAS--KVTSYASLFAQALPRDAHSTPYYCARPQTLPLNYQDRSTQS---SGSLGSSGISSIGMCGLSGPTPV-QP--FLPGQSHQAPGVGDGLRQQLGPRLAWTLTGNQPS-QTPTSKAFPNALS-----RNLTRSRREGDPG-GTSEVTEAALVRDILYVFQGIDGKNIKMSSTENCYKVEAKANLSKSLRDTAVRLAELGWLHNKIRKYADQ---RSLDRSFGLVGQSFCAALHQELKEYYRLLSVLHSQLQLEDDQGVN-VGLESSLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMKSLVQHILSLVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYTLRKSMIPSFITMDQSRKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPRDAADLFTDLENAFQGKIDAAYFETSKYLLDVLNRKYSLLEHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGILETAVRATNAQFDSPEILKRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHYLRVFNFLWRAKRMEYILTDIRKGHMCNAKLLRNMPEFSG--------VLHQCHILASEMVHFIHQMQYYITFEVLECSWDELWNRVQQAQDLDHIIAAHEAFLDTITSRCLLDSNSRVLLNQLRAVFDQIIELQNAQDTMYRAALEELQRRLQFEEKKKQRETEGQWGVTAAEEEEENKRIREFQDSIPKMCSQLRILTHFYQGVVQQFLVLLTTSSDESLQFLSFRLDFNEHYKAREPRLRVSLGS-RGRRSSHT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58854-1", "uniprot_id": "GCP3_MOUSE", "id": "P58854-1", "name": "Gamma-tubulin complex component 3", "aln": "MATPDQKSPNVLLQNLCCRILGRS---------EADVAQQFQFAVRVIGSNFAPTVERDEFLVAEKIKKELIRQRREADAALFSELHRKLHSQG---VLKNKWSILYLLLNLSEDPRKQAS--KVTSYASLFAQALPRDAHSTPYYYARPQTLPLNYQDRSTQAQ-SSGSLGSSGISSIGMCGLSGPTPV-QP--FLPGQSHQAPGVGDGLRQQLGPRLAWTLTGNQPSSQTPTSKGFPNALS-----RNLTRSRREGDPG-GTLEVTEAALVRDILYVFQGIDGKNIKMSSTENCYKVEAKANLNKSLRDTAVRLAELGWLHNKIRKYADQ---RSLDRSFGLVGQSFCAALHQELKEYYRLLSVLHSQLQLEDDQGVN-LGLESSLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMKSLVQHILSLVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYTLRKSMIPSFITMDQSRKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPRDAADLFTDLENAFQGKIDAAYFETSKYLLDVLNKKYSLLEHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGILETAVRATNAQFDSPEILKRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHYLRVFNFLWRAKRMEYILTDIRKGHMCNAKLLRNMPEFSG--------VLHQCHILASEMVHFIHQMQYYITFEVLECSWDELWNRVQQAQDLDHIIAAHEAFLNTITSRCLLDSNSRVLLNQLRAVFDQIIELQNAQDVMYRAALEELQRRLQFEEKKKQREIEGQWGVTAAEEEEENKRIREFQDSIPKMCSQLRILTHFYQGVVQQFLVLLTTSSDESLQFLSFRLDFNEHYKAREPRLRVSLGS-RGRRSSHT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96CW5-1", "uniprot_id": "GCP3_HUMAN", "id": "Q96CW5-1", "name": "Gamma-tubulin complex component 3", "aln": "MATPDQKSPNVLLQNLCCRILGRS---------EADVAQQFQYAVRVIGSNFAPTVERDEFLVAEKIKKELIRQRREADAALFSELHRKLHSQG---VLKNKWSILYLLLSLSEDPRRQPS--KVSSYATLFAQALPRDAHSTPYYYARPQTLPLSYQDRSAQSAQSSGSVGSSGISSIGLCALSGPAPAPQS--LLPGQSNQAPGVGDCLRQQLGSRLAWTLTANQPSSQATTSKGVPSAVS-----RNMTRSRREGDTG-GTMEITEAALVRDILYVFQGIDGKNIKMNNTENCYKVEGKANLSRSLRDTAVRLSELGWLHNKIRRYTDQ---RSLDRSFGLVGQSFCAALHQELREYYRLLSVLHSQLQLEDDQGVN-LGLESSLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMRSLVQHILSLVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYTLRKSMIPSFMTMDQSRKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPQDAADLFTDLENAFQGKIDAAYFETSKYLLDVLNKKYSLLDHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGILETAVRATNAQFDSPEILRRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHYLRVFNFLWRAKRMEYILTDIRKGHMCNAKLLRNMPEFSG--------VLHQCHILASEMVHFIHQMQYYITFEVLECSWDELWNKVQQAQDLDHIIAAHEVFLDTIISRCLLDSDSRALLNQLRAVFDQIIELQNAQDAIYRAALEELQRRLQFEEKKKQREIEGQWGVTAAEEEEENKRIGEFKESIPKMCSQLRILTHFYQGIVQQFLVLLTTSSDESLRFLSFRLDFNEHYKAREPRLRVSLGT-RGRRSSHT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RN46-1", "uniprot_id": "F1RN46_PIG", "id": "F1RN46-1", "name": "", "aln": "MATPDQKSPNVLLQNLCCRILGKS---------EADVAQQFQYAVRVIGSNFAPTVERDEFLVAEKIKKELTRQRREADAALFSELHRKLHSQG---VLKNKWSILYLLLSLSEDPRKQPS--KVSGYAALFAQALPRDAHSTPYYYARPQSLPLNYQERGAPSAQSAGSAGSSGVSSLGTYALNGPTPPPPPPALLPGQPLPAPGVGDGLRQQLGSRLAWTLTASQPSLPSTTSKAVPSSGS-----RGAARPRREGDAAAGAVEVTEAALVRDILYVFQGIDGKHVKMSNADNCYTVEGKANLSKSLRDTAVRLAELGWLHNKIRKYTDQ---RSLDRSFGLVGQSFCAALHQELREYYRLLSVLHSQLQLEDDQGVN-LGLESSLTLRRLLVWTYDPKMRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYARSLVQHILSLVSHPVLSFLYRWIYDGELEDTYHEFFVASDPAVKADRLWHDKYALRKPMIPSFMTMDQCRKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPQDAADLFTDLENAFQGKIDAAYFETSKYLLDVLNKKYSLLDHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGILETAVRATNAQFDSPEILKRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHYLRAFNFLWRAKRVEYILTDIRKGHMCNARLLRSMPEFSG--------VLHHCHILASEMVHFIHQMQYYVTFEVLECSWDELWNRVQRAQDLDHIIAAHEAFLGTVISRCLLDSDSRALLNQLRAVFDQIIELQNTQDAIYRAALEELQRRLQFEEKKKQREAEGQWGVSAAEEEQEKRRVQEFQESIPKMCSQLRILTHFYQGVVQQFLVSLTTSSDESLRFLSFRLDFNEHYRAREPRLRVSLGT-RGRRSSHT", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "E1BNG7-1", "uniprot_id": "E1BNG7_BOVIN", "id": "E1BNG7-1", "name": "", "aln": "MATPDQKSPNVLLQSLCCRILGRS---------EADVAQQFQYAVRVIGSNFAPTVERDEFLVAEKIKKELTRQRREADAALFSELHRKLHSQG---VLKNKWSVLYLLLSLSEDPRRQPG--KVSNYATLFAQALPRDAHSTPYYYARPQTLPLNYQERSAPSAQSSGSLGSSGISSIGVHT-NGPTPPPP--SLLPGQSHLGPGTGDCLRQQLGARLAWTLPASQPSLQTTTSKGVPSAAS-----RSMTRPRRDGDAG-GAVEVTEAALVRDILYVFQGIDGRNIKMSSADNCYKVEGKANLNKSLRDTAMRLAELGWLHNKIRKYTDQ---RSLDRSFGLVGQSFCAALHQELKEYYRLLSVLHSQLQLEDDQGVN-LGFESSLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPSMRSLVQHILSLVSHPVLSFLYRWIYDGELEDTHHEFFVASDPTVKTDRLWHDKYTLRTSMIPSFMTMDQSRKVLLIGKSINFLHQVCHDQTPPTKMIAVPRSAEPLQDAADLFTDLENAFQGKIDAAYFETSKYLLDVLNRKYSLLDHMQAVRRYLLLGQGDFIRHLMDLLKPELARPATTLYQHNLTGILETAVRATNAQFDSPEILKRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHYLRVFNFLWRAKRMEYILTDIRKGHMCNAKLLRSLPEFSG--------VLHHCHILASEMVHFIHQMQYYITFEVLECSWDELWNQVQQAQDLDHIIAAHEAFLGTVISRCLLDSDSRALLNQLRAVFDQIIELQSTQDAICRAALEELQRRLQFEDKKKQREAEGQWGVTAAEEEQENQRIREFRESIPKMCSQLRILTHFYQGVVQQFLVLLTTSSDESLRFLSFRLDFNEHYRAREPRLRVSLGA-RGRRSSHT", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1QA15-1", "uniprot_id": "F1QA15_DANRE", "id": "F1QA15-1", "name": "", "aln": "MATLDQKSPNVLLQSLCCKITGKS---------EADVAHQFQYAVRVIGSNYAPTIERDEFLVSEKIKKELLKQRREADAALFSELHRKLQTQG---VLKHRWSILYLLLSLCEDPRKPSGRVPVCSYGALLAQALPRDVHSTPFYYARPQSLPLSYPERSATAH--NSSMATSGISSMGVFSINGPGPTPPS--LLTGAGTQA--VGESMR---GSRLAWTLPVSSSPSGAAAAPRPPSGPSSSPAPKPLQRPRRDGDGS---ADIGEAALVRDILYVFQGIDGKFIKMCSPENCYKIDSKVPLCKSLRDTSSRLAELGWLHNKIRKYTDS---HSLDRAFGLVGQSFCAALHQELKEYYRLLSVLHAQLQVEDDQGVN-MSVDSSLTLRRLLVWTYDPKVRLKTLAALVDYCQGRKGGELATAVHAYGKTGDPNMRALIQHILGLVSHPILNFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYSLRKSMIPSFITMDQARKVLLIGKSINFLHQVCHDRTPPGKIMPASKSKDSPKDAAELFTDLEGTFQSKIDAAYFETSKYLLDVLNKNYQLLEHLQAMRRYLLLGQGDFIRHLMDLLKPELARPATTLYQHNLTGILETAVRATNAQFDSPEILKRLDVRLLEVSPGDTGWDVFSLDYHVEGPIATVFTRECMSHYLRVFNFLWRAKRMEYILTDIWKGQMCNAKLLKSMPELSG--------VLHQCHVLASEMVHFIHQMQYYITFEVLECSWDELWNKVQQAQDLDHIIAAHDVFLDTIISRCLLDVNNRSLLNQLRAVFDQIIEFQNAQDTLYRSALEELQLRIQFEDKKRQREEMAEWGVTAEQEAEENRRVQEFKDTIPKMCSQLRLLTHFYQGIVQEFLRLLMTCSDESLQFLSFRLDFNEHYKARDPRLRPSLGATRGRRSSNI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9FG37-1", "uniprot_id": "GACP3_ARATH", "id": "Q9FG37-1", "name": "Gamma-tubulin complex component 3", "aln": "MEDDDQQKAADLVQELVLRLVSQNPQTPNLDPNSPAFLKTLRYAFRILSSRLTPSVLPDATAIAESLKRRLATQGKSSDALAFADLYTKFASKTGPGSVNNKWALVYLLKIVSDDRKSAIN-----------------------------------------------GLDSSVLLPNLGIGD--------------TGNGVLSRGEAKKKDWSNGVLLVSKDPENLRDIAFREYAILVKEEN----------------------EVTEEVLVRDVLYASQGIDGKYVKFNSEIDGYAVQESVKVPRATRIMVRMLSELGWLFRKVKTFITESMDRFPAEDVGTVGQAFCAALQDELSDYYKLLAVLEAQAMNPIPLVSESASSNNYLSLRRLSVWFAEPMVKMRLMAVLVDKCKVLRGGAMAGAIHLHAQHGDPLVHDFMMSLLRCVCSPLFEMVRSWVLEGELEDTFGEFFVVGQP-VKVDLLWREGYKLHPAMLPSFISPSLAQRILRTGKSINFLRVCCDDHGWADAASEAAAASGTTTRRGGLGYGETDALEHLVTEAAKRIDKHLLDVLYKRYKFKEHCLAIKRYLLLGQGDFVQYLMDIVGPKLSEPANNISSFELAGFLEAAIRASNAQYDDRDMLDRLRVKMMPHGSGDRGWDVFSLEYEARVPLDTVFTESVLSKYLRVFNFLWKLKRVEHALIGIWKTMKPNCITSNSFVKLQSSVKLQLLSALRRCQVLWNEMNHFVTNFQYYIMFEVLEVSWSNFSKEMEAAKDLDDLLAAHEKYLNAIVGKSLLGEQSQTIRESLFVLFELILRFRSHADRLYEGIHELQIRSKESGREKNKSQEPGSWIS-----EGRKGLTQRAGEFLQSMSQDMDSIAKEYTSSLDGFLSLLPLQQSVDLKFLFFRLDFTEFYSRLHSKG---------------", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 249, "similar_positions": 303, "identity": "26.43%" }, { "cls_id": "homologset.oma.815787", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A2A9-1", "uniprot_id": "D4A2A9_RAT", "id": "D4A2A9-1", "name": "Gamma-tubulin complex component", "aln": "MARPKSSG----SRMDRQLEHDVRELVRQVTGLQDEADSN--------FQMALDFAWSNFRFHRFLDVNSHKVEKTIEGIYEKLTIHSDLSKAASWKRLTKEFLNVALPSTEKIKTDTHYSILSLLLCLSDSPSNSNYVETPREKEVE-------------------------------------KKDDFDWGKYLMEGEEVGLGPDMDTPNWSEDSDDEDTQQPLSREDSGIQVDRTPLEEQDHNRKGGLQVCWED-EPDSRSWLEQHVVHQYWTTRRSRIPHSSHLHSNLAAVWDQHLYSSDPLYVPDDRVVVTETQVIRETLWLLSGVKKLFIFQLIDGKVTVRDNIIVTHLTHSCLRSVLEQIAAYGQVVFRLQEFIDEVMGHSSESPSPGNGPIPKKTPDAPFRTYQAFMWALYKYFINFKEELTEIEKSVISNDTTITLAIVVNKLAPRLAQLKVLDKVFSTGVAEVPPDTRNVVRASHLLNTLYKAILEYDNVGEASEQTVSLLFSLWVETVRPYLQTVDEWIVHGHLWDGAREFIIQRNKNVPVNHRDFWYATYTLYSVSEKTENEDKVSDSASASSGSDQGPSSRQHTMVSFLKPVLKQIIMAGKSMQLLKNLNCAEGSACQAAARDAERKSLYTLFLESIQLRLQHGEDSTTHILNEEQATKENLIKMQSIAERHLELDDIHDPLLAINFARLYLEQSDFHEKFAGGDICVDRSSESVTCQTFELTLRSCLYPHIDKQYLHCCGNLMQTLKRDFRLVEYLQAMRNFFLMEGGDTMYDFYTSIFDKIREKETWQNVSFLNVQLQEAVGQRYPEDSLRLSISFENVDTTKKKLPVHILDGLTLSYKVPWPVDIVISVECQKIYNQVFLLLLQIKWAKYSLDVLLFGELANAAEKSQAKEDVLRDQDTPAQFGPPKESLRQQIHRMFLLRVKLMHFVNSLHNYIMTRILHSTGLEFQHQVEEAKDLDQLIKIHYRYLSTIHDRCLLREKVSFVKEAIMKVLNLALMFAEGWQAGLGAWQMESIEKMESDFKNCHMFLVTILNKAVCRGSFPHLESLALSLMAGMEQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BKN5-1", "uniprot_id": "GCP5_MOUSE", "id": "Q8BKN5-1", "name": "Gamma-tubulin complex component 5", "aln": "MARPKSSG----SRMDRQLEHDVCELVRQVTGLQDEADPN--------FQLALDFVWSNFRFHRFLDVNSHKVEKTIEGIYEKFTIHSDLNKAASWKRLTKEFLNASLPSTEKIKTDAHYSILSLLLCLSDSPSNSNYVETPREKEVE-------------------------------------KKDDFDWGKYLMEGEEIGLGPNIDTPNWSEDSDDEDAQQPLSREDSGIQVDRTPLEEQDHNRKGGPQVCWED-EPDSRSWLEQHVVHQYWTTRRFRIPHSAHLHSNLAAVWDQHLYSSDPLYVPDDRVVVTETQVIRETLWLLSGVKKMFIFQLIDGKVTVRNNIIVTHLTHSCLRSVLEQIAAYGQVVFRLQEFIDEVMGHSSESLPPGNGPIPKKQPDAPFRTYQAFMWALYKYFINFKEELTDIEKCVISSDTTITLAIVVNKLAPRLAQLKVLDKVFSTGVAEVPPDTRNVVRASHLLNTLYKAILEYDNVGEASEQTVSLLFSLWVETVRPYLQTVDEWIVHGHLWDGAREFIIQRNKNVPVNHRDFWYATYTLYSVSEKTENEDKVSDSASASSGSDQGPSSRQHTMVSFLKPVLKQIIMAGKSMQLLKNLNCAEGPACQAAARDAERKSLYTLFLESIQLRLQHGEDSAPHIVNEDQTTKENLIKMQSIAERHLELDDIHDPLLAINFARLYLEQSDFHEKFAGGDICVDRSSESVTCQTFELTLRSCLYPHIDKQYLHCCGNLMQTLKRDFRLVEYLQAMRNFFLMEGGDTMYDFYTSIFDKIREKETWQNVSFLNVQLQEAVGQRYPEDSLRLSISFENVDTTKKKLPVHILDGLTLSYKVPWPVDIVISVECQKIYNQVFLLLLQIKWAKYSLDVLLFGELGNAAERSQAKEDIPRDQDTPSQFGPPKESLRQQIHRMFLLRVKLMHFVNSLHNYIMTRILHSTGLEFQHQVEEAKDLDQLIKIHYRYLSTIHDRCLLREKVSFVKEAIMKVLNLALMFAEGWQAGLGAWQMESIEKMESDFKNCHMFLVTILNKAVCRGSFPHLESLALSLMAGMEQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RT8-1", "uniprot_id": "GCP5_HUMAN", "id": "Q96RT8-1", "name": "Gamma-tubulin complex component 5", "aln": "MARHGPPW----SRLDAQQERDVRELVRGVAGLQDEADPN--------FQLALNFAWSNFRFHRFLDVNSHKIEKTIEGIYEKFVIHSDLSKAASWKRLTEEFLNAPLPSIKEIKTDAHYSILSLLLCLSDSPSNSSYVETPRNKEVE-------------------------------------KKDDFDWGKYLMEDEEMDIGPYMDTPNWSEESEEENDQQPLSREDSGIQVDRTPLEEQDQNRKLDPCISWKD-EPDDRSWLEHHVVHQYWTARPSQFPHSLHLHSNLAAVWDQHLYSSDPLYVPDDRVLVTETQVIRETLWLLSGVKKLFIFQLIDGKVTVRNNIIVTHLTHSCLRSVLEQIAAYGQVVFRLQEFIDEVMGHSSESMLPGSGSVPKKSTEAPFRTYQAFMWALYKYFISFKEELAEIEKCIINNDTTITLAIVVDKLAPRLSQLKVLHKVFSTGVAEVPPDTRNVVRASHLLNTLYKAILEYDNVGEASEQTVSLLFSLWVETVRPYLQTVDEWIVHGHLWDGAREFIIQRNKNVPVNHRDFWYATYTLYSVSEKTENEEKMSDNASASSGSDQGPSSRQHTMVSFLKPVLKQIIMAGKSMQLLKNLQCAESTTCQAGARDAERKSLYTLFLESVQSRLRHGEDSTPQVLTEQQATKENLMKMQSIAESHLELDDVHDPLLAINFARMYLEQSDFHEKFAGGDVCVDRSSESVTCQTFELTLRSCLYPHIDKQYLDCCGNLMQTLKKDYRLVEYLQAMRNFFLMEGGDTMYDFYTSIFDKIREKETWQNVSFLNVQLQEAVGQRYPEDSSRLSISFENVDTAKKKLPVHILDGLTLSYKVPWPVDIVISLECQKIYNQVFLLLLQIKWAKYSLDVLLFGELVSTAEKPRLKEGLIHEQDTVAQFGPQKEPVRQQIHRMFLLRVKLMHFVNSLHNYIMTRILHSTGLEFQHQVEEAKDLDQLIKIHYRYLSTIHDRCLLREKVSFVKEAIMKVLNLALMFADGWQAGLGTWRMESIEKMESDFKNCHMFLVTILNKAVCRGSFPHLESLALSLMAGMEQS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0XEE8-1", "uniprot_id": "A0A8V0XEE8_CHICK", "id": "A0A8V0XEE8-1", "name": "Gamma-tubulin complex component", "aln": "MAAPLLASPGRRSRFEQEQDRAVRALIRSVTGLPEEEEEREEEPGGGRFQTALNFAWSNFRFHRFLDVNSHKVERTIEGIHEKLIVHSDLGKAASWKRLTEKFLNSPLPSIEETKTDTHYSILSLLLCLSDSPSNTTYVEKPREKEADSFLNDLCTFPRRCFECTFSPFQECEYEEVISNSSNYKKEEKFDWGKYLLEGEEIYFGPGIDSPDWSGESEEEEDTQPLSREDSGIQVDRTPLEDQDPHKKTVPNVSWKVGEPDARSWLEQHVVPQYWTGRAPRFSHSLHLHSNLAAVWDHHLYTSDPLYVPEERTLVTETQVIRETLWLLSGVKKLFIFQLNDGKVVVRNDIIVTHLTHNCLRSLLEQIAAYGQVVFRLQKFIDEVMGHSPE-----NVSTPKKTTEAPFRTYQAFMWALYKYFISFKEELTEIEKCIINKDKTVTLSIVIDKLSPRLAQLKVLHKVFSTGVAEVPPDTRNVVRASHLLNTLYKAILEYDSVGEASEQTVSLLFSLWVETVRPYLQTVDEWIVHGNLFDPAKEFIIQRNKNVPVNHRDFWYATYTLYSVSEKTENEEKMSDNASASSGSDQAPSSRQHTMVSFLKPVLKQIIMAGKSMQLLKNLQCKDGSPQQAASRDAERKSLYTLFLESVQSRLRHGEESVPDIITEQQATKQSLIKMQSIAERHLELDDVHDPLLAINFARLYLEQSDFHEKFTGGDVCVDRSSESVTCQTFELTLRSCLYPHIDKQYLECCGNLMQTLKKDYRLVEYLQAMRNFFLLEAGDTMYDFYTSIFDKIREKETWQNVAFLNVQLQEAVGQRYPEDSSRLSISFESVDTAKKKLPVHTLDGLTLSYKVPWPVDIVISLECQKIYNQVFLLLLQIKWAKYSLDVLRFDELVCAAENPQVKEGTLLEHGTLPRFGPQTESIKQQIHRMFLLRVKLMHFVNSLHNYIMTRILHSTGLEFQHQVEEAKDLDQLIKIHYRYLSTIHDRCLLREKVSFVKEAIMKVLNLVLMFADRWQAGLGAWKMESIEKMESDFKNCHMFLVTVLNKAVCRGSFPHLESLALSLMAGMEQS", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . **:: : :: * *:* *:** :* : . ** **:*.****************:*:*****:**: :****.*********::*** .*** :: ***:*****************:.***.**:**.: *::.*******:*.**: :** :*:*:** :*::*: ******************:** ::* :.*: *** *****:*** **** * ::.** ***********:***:*******::*.:*******************:***** ****.**::********.****:***************:*********.* . . *** .:******************.*****::***.:*..*.*:**:**::**:***:*****.***********************************.**********************************:*:* *:**********************************:*:**.*********.********************************:* :... **.:***************:* **:***:*...::.*:*:**:.*:******* ******:***********:***********:***:*******************************.**********:*:**************:*.************************:****************** *******.***:******* *******************:************************** *.** :**..: **. ::.* .:*** .*.::***********************************************************************************.****: ******:*:********************:***************************", "identical_positions": 812, "similar_positions": 150, "identity": "75.61%" }, { "cls_id": "homologset.oma.815788", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A709-1", "uniprot_id": "D4A709_RAT", "id": "D4A709-1", "name": "Gamma-tubulin complex component 6", "aln": "MASITQLFDDLCEALLP--AAQARPGQRSVNRKKAKLSLKRVAYNALFANLFQEDTHQRQPDS-KLPVKNKVLMLSFDLRVGGLGPEADRLEELVEKLETAPDCPFVEVGSVLDLLVQLAGSGPPQVLRRKRDYFFNNKHAGRNIPYSGYDCYDLSVFEMDVRSLISGEENLCHNMVQEALQVMEAAPGTGLTTVGLFSTGDSCGDRFERDTRVSLFGALVHSRTYDMDVRLDLPPVPDSADFSGLAIKVPQIVDQWEDEGFQSASNLTPDSQSEPSMTPDLDLWEAVLTYEASKRRCWERIGCPPGHREEPYLTEAGRDAFDRFCRLCHGELQALSGGLLQTPRPVLVEESELVKDSLNVLLGVVSATFSLCQPTQAFVVEPGVHVSGASPESISSILSEVAEYGTCYTRLSHFSLQPVVGSLCSRGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLLTIGFLFKKLGRQLRYLAELCGVGTVSLATSGE-PRAVFPTGVKLLSYLYQEALDNCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNHEYLSFRDKFYWTHGYVLISKEVEDCVPVFLKHIAHDVYVCGKTINLLKLCCPRHYLCWSDVPVPRISVIFSLEELKEIEKDCAVYVGRMERVARYSSISKEEKELRMEIAKQELIVHAREAASRVLSELSDRQMSEQIALDTRKREQFQRLKEQFVKDQERRLAARQEELGDDFSYAHELRAREKRLKALEEELERKARQALVDHYSKLSAEAARREQKALWRIRRHRLESARLRFLLEDQKCIQEMLRDM-EAHQPQEPLSVLPSTCSQVTSLGPEHEGEGHSCDLESTELR---CDCSNQPCASTPSVLKSGAGQAEE--------AGPFSTGLSITDFLPMGSGDEQPVGDTGAPFLEVALQSICSDLSPITPGP-ALTAGGLQPTQSEYDFNTILRPAMATPPLPGPFRDVQNSVDSEKQHLLRDMPTKPDSCIHDMQETLPCLHPLSHVTPAEGSLQPVGQLLEHMSETTVATESHASGMAPCQQLSISR-HVSDANIKVGDYMSDVALPRPRWNIHGHVSEANIGVGENVSDVAPSRPRWNVHGHVSDASIKVGENVSDVAPSRPRWNVHGHVSDASIKVGENVSEVAPSRPRWNVHGHVSDASIKVGENVSDVAPSRPRWNVHGHVSDASIKVGENVSDVAPSRPRWNVHGHVSEASIRIGENVS--DVDLQ---PHGHV----------------------------QPPLILEEPFPEAEP-DLKSHQCPPDHVSQTVLCVEAQSPAQECEPQLPEEMKPTICLSLGSTEEGSLQTKTLVTEPS--------MLGNGIPEEKGPRRNRDAEDLSPCLPSSPQED-TLPSSPGPSEEVPSTEAEEARRWGKEQAYLADLTKLYRLEQYPDSYESMSEPPMAHLVHHMLPRAFAFPVDPQVQSAVDESAVQLSELLTLPVLMKRSLMAPLAAHVSLVNKAAVDYFFVELHLETHFEALRHFLLMEDGEFAQSLSDLLFEKLGAGQTPGELLNPLVLNSILSKALQYSLHGDTPHATNLSFALKYLPEVFAPNAPDVLSCLELRYKVDWPLNIVITESCLNKYSGIFSFLLQLKLMMWTLKDICFHLKRTALVSHTAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVSWCEFRARLAVVGDLEEIQRAHAEYLHRAVFRGLLTEKAAPVMNIIHSIFSLVLKFRSQLISQNWGPATGPRGAEHPNFPLMQQSYSTFKYYSHFLFKVVTKLVNRG----YQPHLEDFLLR---------INFNNYYQDS-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G5E8P0-1", "uniprot_id": "GCP6_MOUSE", "id": "G5E8P0-1", "name": "Gamma-tubulin complex component 6", "aln": "MASITQLFDDLCEALLP--AAQARPGQRSVNRKRAKRSLKRVAYNALFANLFQEDTHQRQPDSSKLPVKNKVLMLSFDLRVGGLGPEADRLEELVEKLEAAPDCPFVEVASVLDLLVQLAGSGPPQVLRRKRDYFFNNKHAGRNIPYSGYDCYDLSVFEMDVRSFISGEENLCHHTVQEALQVMEAAPGTGLPTVGLFSIGDSCGDRFERDTRVSLFGALVHSRTYDMDVRLDLPPVPDSADFSGLAIKVPQIVDQWEDEGFQSASNLTPDSQSEPSMTPDLDLWEAVLTYEASKRRCWERIGCPPGHREEPYLTEAGRDAFDRFCRLRHGELQALSGGLLQAPKPVLVEESELVKDSLNVLLGVVSATFSLCRPTQAFVVEPGVHVSGASPESISSILSEVAEYGTCYTRLSHFSLQPVVGSLCSRGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLLTIGFLFKKLGRQLRYLAELCGVGTVSLATSGE-PRAVFPTGVKLLSYLYQEALDNCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNHEYLSFRDKFYWTHGYVLISKEVEDCVPVFLKHIAHDVYVCGKTINLLKLCCPRHYLCWSDVPVPRISVIFSLEELKEIEKDCAVYVGRMERVARHSCISKEEKELRMEIAKQELIVHAREAASRVLSELSDRQMAEQIAQDTRKREQFQRLKEQFVKDQERRLAARQEELDDDFSYARELRDREKRLKALEEELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLRFLLEDQKCIQEMLRDM-EAQQPQEPPSVFPSTGSQVTSTGPEHAGEGHSCDPGFTELH---WGCPSLPCASTPSVPKSATEGADDS------GAGPFSTGLSITDFLPVDSGEEQPVENTGVPFLEVALQTICSDLSPVAPEPAALTAGGPQATQSEYDFNTILRPAMATSLSPGPFQDVQNSVDSDKQHLLGDMSTKVDSYIHDMQETLPCPHPLSHATPVEGSLQPVGQLLEHMSETTVSTESHASGMAPCQQLSISR-HVSDANIKVGDYMSDVALPRPRWNVHGHVSEASIGVGENMAEVAPSRPRWNVHGHVSDASIKIGENMSDVAPSRTRWNIHGHVSDASIKVGENVSDVTPSRPRWNVHGHVSEASIKVGENVSDVTPSRPRWNVHGHVSEASIKVGENVSDVTPSRPRWNVHGHVSDASIRIGENVSDTDLDLQ---QRGCA----------------------------QPPLILEEPLPEAEA-DLKPHQCPPAHVSEAVLGVEAQSPALECGPQLPEKTKPTVCSGFGRTEEGSLQTKTLVAEPS--------MLGSGIPEEKGPGKSRDAEDLSPCLPSSSQEDTAVPSSPGPSDEVSNTEA-EARRWGKEQAYLTDLTKLYHLEQYPDSYDSMSEPPVAHLVHHMLPRAFAFPVDPQVQSAVDESAVQLSELLTLPVLMKRSLMAPLAAHVSLVSKAAVDYFFVELHLETHFEALRHFLLMEDGEFAQSLSDLLFEKLGAGQTPGELLNPLVLNSILSKALQYSLHGDTPHASNLSFALKYLPEVFAPNAPDVLSCLELRYKVDWPLNIVITESCLNKYSGIFSFLLQLKLMMWTLKDICFHLKRTALVSHTAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVSWCEFRARLAVVGDLEEIQRAHAEYLHRAVFRGLLTEKAAPVMNIIHSIFSLVLKFRSQLISQNWGPATGPRGAEHPNFPLMQQSYSTFKYYSHFLFKVVTKLVNRG----YQPHLEDFLLR---------INFNNYYQDS-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RT7-1", "uniprot_id": "GCP6_HUMAN", "id": "Q96RT7-1", "name": "Gamma-tubulin complex component 6", "aln": "MASITQLFDDLCEALLP--AAKTHLGQRSVNRKRAKRSLKKVAYNALFTNLFQDETQQLQPDMSKLPARNKILMLSFDLRVGGLGPKADRLEELVEELEAAPCCPLLEVGSVLDLLVQLAGSGPPQVLPRKRDYFLNNKHVGRNVPYSGYDCDDLSVFEMDVQSLISREECLCHSMIQETLQVMEAAPGTGLPTVGLFSFGDPCGDRFERDTRVSLFGALVHSRTYDMDVRLGLPPVPDNADLSGLAIKVPPSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALTYEASKRRCWERVGCPPGHREEPYLTEAGRDAFDKFCRLHQGELQLLAGGVLQAPQPVLVKECELVKDVLNVLIGVVSATFSLCQPAQAFVVKRGVHVSGASPESISSLLSEVAEYGTCYTRLSHFSLQPVLDSLYSKGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLLTIGFLFKKLGRQLRYLAELCGVGAVLPGTCGGGPRAAFPTGVKLLSYLYQEALHNCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDAYGEFMIQVNHEYLSFRDKLYWTHGYVLISKEVEDCVPVFLKHIAHDIYVCGKTINLLKLCCPRHYLCWSDVPVPRISVIFSLEELKEIEKDCAVYVGRMERVARHSSVSKEEKELRMEIAKQELIAHAREAASRVLSALSDRQMSERMALDARKREQFQRLKEQFVKDQERRQAARQEELDDDFSYARELRDRERRLKSLEEELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLRFLLEDEKHIQEMLKAVSEAHQPQEPPDVLLSVHPQVTSPGPEHPEGGQGCDSGSAEQHSPAWDGWNRPGLLTPQPLKPLAVGAGGRGLQQAEGARPFSDSLSIGDFLPVGPGAEPSVQTGMVPLLEVALQTINLDLPPSAPGEAPAAASTQPSRPQEYDFSTVLRPAVATSPAPGPLQAAECSLGSSGLQLWEDSCGKMDACGSASRETLLPSHPPRRAALEEGSSQPTERLFGQVSGGGLPTGDYASEIAPTRPRWNTHGHVSDASIRVGENVSDVAPTQPRWNTHGHVSNASISLGESVSDVAPTRPRWNIHGHVSNASIRVGENVSDVAPTRPRWNTHGHVSNASIRVGENVSDVAPTRPRWNTHGHVSDASISLGESVSDMAPARPRWNTHGHVSDASISLGESVSDMAPTRPRWNTHGHVSDTSIRVGENVSDVAPIRSRCNTHGHVSDASISLGEPVSDVVSTRPRWNTHVPIPPPHMVLGALSPEAEPNTPRPQQSPPGHTSQSALSLGAQSTVLDCGPRLPVEVGPSLSSPSSGCGEGSISVGENVSDVAPTQPWWPNTPGDSVSEELGPGRSGDTEDLSPNWPLNSQEDTAAQSSPGRGEEA---EASAAEAQGGEQAYLAGLAGQYHLERYPDSYESMSEPPIAHLLRPVLPRAFAFPVDPQVQSAADETAVQLSELLTLPVLMKRSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGEFAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQCSLHGDTPHASNLSLALKYLPEVFAPNAPDVLSCLELRYKVDWPLNIVITEGCVSKYSGVFSFLLQLKLMMWALKDVCFHLKRTALLSHMAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLATVGDLEEIQRAHAEYLHKAVFRGLLTEKAAPVMNVIHSIFSLVLKFRSQLISQAWGPPGGPRGAEHPNFALMQQSYNTFKYYSHFLFKVVTKLVNRG----YQPHLEDFLLR---------INFNNYYQDA-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0XBU0-1", "uniprot_id": "A0A8V0XBU0_CHICK", "id": "A0A8V0XBU0-1", "name": "Gamma-tubulin complex component 6", "aln": "MESITQLFNDLCEAHLTGLPWKVHLGRQKISKRKAKQNLKRVAYNTLFLNLFQDEARKLQSNISRLPVKNKILMLSFNLRVGGLGAQADRLESLVEELEQAEGLPFTEVNAVLDLLVQLAGTGPPQLVPQKKDYFLNNKYVGRNVKYQGYDYYDVSVFEADIQSLITNEECQFNDTIQKTLQIMEAAPGTGLPAIGLFSQNYPAGDKFERETRVSLFGALVHSRTYDMDIKLDLPPVPDNADLSGLAIKVPQSIDQSEDEGFQSASNLTPDSQSEPSMTPDIDLWDAVLTYGPSKRRCWERIGYPPGKKEEPYLTEAGREAFDKFYKLREGEMQLFSSTALQLPQLVLMREPELVKDVLNVLIGVVSTTFSLNQAAQTFIIKEGVYVSGTSPETMHNLLSEVAEYGTYYTRLSRFSLQPVLDSSYSKGLVFQAFTSGLRKYLQYYRACVLSTPPTLSLLTISFLFRKLGRQLRYLAELCGIGITALGISGG-AGASFPTGVKLLSYLYKEALNNCSNEHYPVLLSLLKTSCEPYTRFIYDWVYSGVFRDVYGEFMIQVNEDYLCFRDKHYWTHGYVLISKEVEDCVPVFLKHIANDVYICGKTINLLKLCCPRHYICWSDIPVPRISVIFSLEELKEIERDCAVYVGRMERIARYSSISKEEKDLRMEIAKQELIVHARETASKVLQAINDRQKSERLALDAKKREQFQKLKEQFAKDQERRLAIKQEEIDDDFSYARELREREKRLKALEEELEKKARQELIDHYSKLSDDAARREQRALWKIQRHKLETARLKFLFEDQKRIEEMLEKLPDGSYRR-KLDIIPYTQCHLALDRNTAVEDPHSQVSSVKPLR-----------SNEKVGRKESESGLEN--------ITSTDKPLAMPQLANTNADQLCQPKTAGS---ECSLQSSEQVCSPLCNADSSPESS---VNIEDFLPKPQDEQPVAISLQGSLLDEALRNINSD----LSETSPMSENQPVSEGEGNTLLHQQNEYDFN-TVLRPTAALQGHIR-----VGENVFDVEPRRPRWNIHGHASDANIRVGEYVPEVDTYQPRSSPYGHSSDSHIEISSYTSEVEPTRPRWNIHGHASEAHIKIGEYASEVEPSRPRWSIHGHASEANIRVGEYVSNVAPARPRWNIHGHVSDANIKIGENVSEVVSARPRWNIHGHSSQSHIKIGELVSDTQPVKSRWSPFGHASQSSIQIGKWTPSTEDDPIP--HRKAISG--------------------------PSSDSTVQTLLYNEELSPSEEIRKETKPSQAKESISPQSQPSDIDPVSPDTRDDKKENTTEEKQE--VIAGEVDKDPS-----------------PDSSQSLQAKEPEKAIPQDTVPQEALFSEPSASKTK-DEEGGEEDAWKKEQAYLKALSDQYCIEKYQDSYDLMSELPVSHLLHHVIPRSYTFPVDPMVQSATDETAVQLSELLSLPVLMKRSITAPLVSHVSLVNKAIVDYYFVELNVEKHFEALRHFLLMEDGEFAQSLSDLLFEKLGSGQTPGELLNPLVLNSILNKALQYSLHGDTQLASNLSFALKYLPEVFKPNAPDALSCLELRYKVDWPLNIVITESCMNKYNKIFSFLLQLKHMVWTLKDVWFHLKRTALVSHASNSVQFRQLQLYKHEMQHFVKVIQGYIANQILHVTWCEFGNKLSSVGNLEEIHRTHAEYLNKAIFRGLLTEKAAPVMNIIHSIFSLILKFRSQLISQSWSFDAGKQMAVHPNFGLMQQSYNTFKYYSHFLFKGYPKMVSEDQKQIFQDELEWLLPNSPGSQNTSGNHLSPYYEIYDCFMDRD", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ******:***** *. . :.: *::.:.:::** .**:****:** ****::::: *.: :**.:**:*****:*******.:*****.***:** * *: ** :**********:****:: :*:***:***:.***: *.*** *:**** *::*:*: ** : :*::**:*********.::**** . ..**:***:******************::*.******.**:******** :** ********************:***:***:*.*** .********:* ***::**********:***:* :* .**:* ::. ** *: **:.* ***** ****:****:**** :.:*:*::: **:***:***:: .:********* *****:******:.* *:************:*********************.***:**************:* . . .* . * ************:***.*************************:**********.*********.:**.**** *************************:*:*:****************:****:******************:***********:**:*.:*****:***********.****:**:**. :.*** :*::* *::******:*****.****** * :***:.******:*** **:***:******:**** *:******* :******:***:*:**:**:***:**:**:* *:***. : :. : .:: . ::: :. : * . . *:: :: ... * :**: .* . :. .:: .. . .:* . . : . .:.*. : : * * . :*. * :: . . . : * : : *.***.*:**: :.:* :** . :** *:: * :.. ::* *:*****:***.*:* *::** *:* *:*.**. ***.*:*.*:*** **:*:*:***** *****:*.*.:**.**::..:***** *** *:: *.:** *** * :.**. .**.*::**::*: .. : . * . : *:: : .** : * * . * : . : : .. :. :::: . * .. : : *.*. .. *. ***** *: * :*:* ***: *** *::**:: ::**:::***** ****.**:********:********: ***.:*:***.** ***:****::* *:***************************:***************:*.**** ****** *:***:********* *****.********************.*:.**. :******** *:*:***: ********:** :.*********:**********************:**** :*: **:****:*:*****::*:**************:*******:********** *. * : * **** ******.*********** .*:*... :* .** :* . ::. **: ", "identical_positions": 982, "similar_positions": 385, "identity": "53.25%" }, { "cls_id": "homologset.oma.815790", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9XYP8-1", "uniprot_id": "GCP3_DROME", "id": "Q9XYP8-1", "name": "Gamma-tubulin complex component 3", "aln": "MSQDRIAGIDVATNSTDISNIINEMIICIKGKQMPEVHEKAMDHLSKMIAANSRVIRDSNMLTERECVQKIMKLLSAR--NKKEEGKTVSDHFNELYRKLTLTKCDPHMRHSLMTHLLTMTDNSDAEKAVASEDPRTQCDNLTQILVSRLNSISSSIASLNEMGVVNGNGVGAAAVTGAAAVTGAAAVTGAAAVTGAAASHSYDATQSSIGLRKQSLPNYLDATKMLPESRHDIVMSAIYSFTGVQGKYLKKDVVTGRFKLDQQNIKFLTTGQAGMLLRLSELGYYHDRVVKFSDVSTGFNAIGSMGQALISKLKEELANFHGQVAMLHDEMQRFRQASVNGIANKGKKDSGPDAGDEMTLFKLLAWYIKPLHRMQWLTKIADACQVKK-GGDLASTVYDFLDNGNDMVNKLVEDLLTAICGPLVRMISKWILEGGISDMHREFFVKSIKDVGVDRLWHDKFRLRLPMLPKFVPMDMANKILMTGKSINFLREICE--------------------------------------EQGMMKERDELMK--VMESSASQIFSYTPDTSWHAAVETCYQQTSKHVLDIMVGPHKLLDHLHGMRRYLLLGQGDFISILIENMKNELERPGLDIYANDLTSMLDSALRCTNAQYDDPDILNHLDVIVQRPFNGDIGWNIISLQYIVHGPLAAMLES-TMPTYKVLFKPLWRMKHMEFVLSMKIWKEQMGNAKALRTMKSEIGKASHRLNLFTSEIMHFIHQMQYYVLFEVIECNWVELQKKM-QKATTLDEILEAHEKFLQTILVGCFVSNKASVEHSLEVVYENIIELEKWQSSFYKDCFKELNARKELSKIVEKSEKKGVYGLTNKMILQRDQEAKIFAEKMDIACRGLEVIATDYEKAVSTFLMSLNSSDDPNLQLFGTRLDFNEYYKKRDTNLSKPLTFEHMRMSNVFAVNSRFVICTPSTQE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q95ZG4-1", "uniprot_id": "SPC98_DICDI", "id": "Q95ZG4-1", "name": "Spindle pole body component 98", "aln": "---------------------MNSTFVQIP-----------------KLNINKQVKKKTDSITANTLLPKLMNDTSIQQPNQQQQQQQPQQPQQVTNGITILQNYQPQQPQPATTTTQQLNSANNTPTLVSTKKS-----------VIGINEIPEHLLIRDIIYVFQG---------IDGTYIKYNKQSDSFKIDENTSNTLVNGEPAYISKPKRDLVYRLCEFGWLFKKVRLFITNNDFKKTGLTNQSFCSAINDELIELYR-------------IIAILETQVYK----KFDMVNYGGGGGGSGGSGSGSGLESPSS--------------------VSSGGTTTSTEIPFIDGDSLTLIRLFVWIQSPLKRLKVLGTCVDSITVDMKGGEILSKIDTLSKHGDQDIRILIHNIMFKICQPLFSMIRLWMFKGEINDPYQEFFIRQYESVQLEKTWKEKFAIVARLLPSFISLPLSKRILIIGKSINYMKQFCNNFKEDKNDRYYYYNQEDDDDDDEDHDDNDDDDENENQGEDDEIIERKLLIKESKIIKEKTKELNYINKEVLQEIIELVSRQSSERLLKIVLNRFKFMNHVKALKKYLLLGQGDFIQYLMDLIGEDLLKPTSQIQRHKLVGWMDTAIRNSNAQFEEQDIVNRLDIALLPERPGNIGWDIFSLDYHVDTPLNTILSPNDILRYKKIFHFMWGIKRVEYSLAS-IWRKIR--SSTSLSILSPIGGDIHKSHLIMNEMVHFISNFQYYLMFEVLECSWKNLEKFIDQEATDLDQLIEAHHQYLQDICNKMFLSNSDSCYECFKKLLSIIIKFTLLQTKLIN-----------LSIAIQNEKN-----FNETHQAQVNKEFNSFRNHLNNLYQEYTTSFYKFQSEI----LKVKVNQDLNPISLQYMLDFNEYYEEKKDN-------------------------------", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 196, "similar_positions": 321, "identity": "20.37%" }, { "cls_id": "homologset.oma.815889", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZJB6-1", "uniprot_id": "A0A8I5ZJB6_RAT", "id": "A0A8I5ZJB6-1", "name": "Tubulin-specific chaperone D", "aln": "--------MVLSNEPAASAAEE-EVEDDALVRASTLEAFGESAETRALLRSLPAVHRERAAREVAEERFRVIMDKYQEQPHLLDPHLEWMMNSLLDIVQ--------DETSLPDLVHLAFKFLYIITKVRGYKVFLRLFPHEVADVQPVLDMFTGQNPK---------DHETWETRYMLLLWLSVTCLIPFDFSRLDGNLPTQSG-----------ETRMPIMDRILQIAQSYLVVSDKARDAAAVLVSKFITRPDVKQRKMASFLDWSLCTLAHSSFQTIDGVITMDGMLQALAQIFKHGKREDCLPYANTVLQCLDGCRLP--ESSHTLLRKLGVKLVQRLGLTFLKPKVATWRYQRGCRSLAANLQLRAPG------KSEQKLLSDSLTSDGDEDYDVPEGVETVIEQLLVGLKDKDTIVRWSAAKGIGRMAGRLPRELADDVVGSVLDCFSFQETDKAWHGGCLALAELGRRGLLLPSRLS-------------------------------EVVTVILKALTYDEKRGACSVGANVRDAACYVCWAFARAYEPQELTPFVTAISSALVIAAVFDRNVNCRRAASAAFQENVGRQGTFPHGIDILTTADYFAVGNISNCFLIISVFIAGFQEYTKPMIDHLVSMKINHWDGAIRELSAKALHNLTSLVPEYMATHVFPALLLMTQSPDLHTRHGAILACAEVTYALYELAAQSNRLVTDYLDEKAVQSLKQIHQQVCVS--YKSLFGKIMCCFFSFSFSIVCILIEKLSLSRMPFKGDTVIEGWQWLINDTLRSLHLVSSHSREQIKHCPG--LPVMR-----QRPLLNTSFFPEELIPQYLAELR-SPEEMTRCGFSSALGALPCFLLRGHLQQVLSGLRRVTCTTSPMDVS-------------FAEARRDGLKAISRICQTVGVNTQ---GPPDEVICQENISEVYAALLGCMSDYTTDSRGDVGAWVREASMTSLMDLMLLLAQ------------TEPVLIEAHICERVMCCVAQQASEKIDRFRAHAARVFLTLLHFDSPPIPHVPHRKELESLFPRSDVATVNWNAPSQAFPLITQLLGLPTYRYHVLLGLAVSVGGLTESTVRHSTQSLFEYMKGIQKDAQVLES-----FSETLLKVFEDNLLNDRVSVSLLKMLDQLLANGCFDIFTAEENHPFCVKLLTLCKEEIKKSKDIQKLRSSIAVLCGMVQFSGDVRKKVLLQLFLLLGHPFPVIRKSTASQVYEMVLTYSDLVDA--EVLDEVMSVLSDTAWDSELPVVRGQRNHLCDLLGVPRPQLVPKVILVVVPVLPVVLSSGLK-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BYA0-1", "uniprot_id": "TBCD_MOUSE", "id": "Q8BYA0-1", "name": "Tubulin-specific chaperone D", "aln": "--------MVLSNEPAASAAEE-EVEDDALVRASALEAFGESAETRALLRSLPAVHRERASREVAEERFRVIMDKYQEQPHLLDPHLEWMMNSLLDLVQ--------DETSLPDLVHLAFKFLYIITKVRGYKVFLRLFPHEVANVQPVLDMFTGQNPK---------DHETWETRYMLLLWLSVTCLIPFDFSRLDGNLSTQTG-----------ETRVPTMDRILQIAESYLVVSDKARDAAAVLVSKFITRPDVKQRKMASFLDWSLCTLAHSSFQTIEGVITMDGMLQALAQIFKHGKREDCLPYANTVLQCLDGCRLP--ESSHTSLRKLGVKLVQRLGLTFLKPKVATWRYQRGCRSLAANLKLCAPG------KSDQKLLSDSLTSDGDEDYDVPEGVETVIEQLLVGLKDKDTVVRWSAAKGIGRMAGRLPRELADDVVGSVLDCFSFQETDKAWHGGCLALAELGRRGLLLPSRLS-------------------------------EVVTVILKALTYDEKRGACSVGANVRDAACYVCWAFARAYEPQELTPFVTAISSALVIAAVFDRNVNCRRAASAAFQENVGRQGTFPHGIDILTTADYFAVGNISNCFLIISVFIAGFQEYTKPMIDHLVSMKINHWDGAIRELSAKALHNLTPQVPEYIAMHVFPALLLMTQSPDLHTRHGAILACAEVTYALYKLATQSNRLVTDYLDEKAVQSLKQIHQQLCDRHLYRGLGGELMR-------QAVCILIEKLSLSRMPFKGDATVEGWQWLINDTLRSLHLVSSHSRQQIKEVAVSALTALCSEYYVKEPGEAGSSIAKELIPQYLAELQ-SPEEMARCGFSSALGALPGFLLRGHLQQVLSGLRRVTCIS-PNDVS-------------FAEARRDGLKAISRICQTVGVNTR---GPPDEVICKENISEVYAALLGCMSDYTTDSRGDVGAWVREAAMTSLMDLMLLLAR------------TEPVLIEAHICERVMCCVAQQASEKIDRFRAHAARVFLTLLHFDSPPIPHVPHRQELESLFPRSDVATVNWNAPSQAFPLITQLLGLPTYRYHVLLGLAVSVGGLTESTVRHSTQSLFEYMKGIQKDAQVLQS-----FSETLLKVFEDNLLNDRVSVSLLKMLDQLLANGCFDIFTAEENHPFCVKLLTLCKEEIKKSKDIQKLRSSIAVLCGMVQFNGDVRKKILLQLFLLLGHPFPVIRKSTASQVYEMVLTYSDLVDA--EVLDEVMSVLSDTAWDAELPVVREQRNRLCDLLGVPRPQLVPKPIPGS--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BTW9-1", "uniprot_id": "TBCD_HUMAN", "id": "Q9BTW9-1", "name": "Tubulin-specific chaperone D", "aln": "--------MALSDEPAAGGPEE-EAEDETLAFGAALEAFGESAETRALLGRLREVHGGGAEREVALERFRVIMDKYQEQPHLLDPHLEWMMNLLLDIVQ--------DQTSPASLVHLAFKFLYIITKVRGYKTFLRLFPHEVADVEPVLDLVTIQNPK---------DHEAWETRYMLLLWLSVTCLIPFDFSRLDGNLLTQPG-----------QARMSIMDRILQIAESYLIVSDKARDAAAVLVSRFITRPDVKQSKMAEFLDWSLCNLARSSFQTMQGVITMDGTLQALAQIFKHGKREDCLPYAATVLRCLDGCRLP--ESNQTLLRKLGVKLVQRLGLTFLKPKVAAWRYQRGCRSLAANLQLLTQG------QSEQKPL--ILTEDDDEDDDVPEGVERVIEQLLVGLKDKDTVVRWSAAKGIGRMAGRLPRALADDVVGSVLDCFSFQETDKAWHGGCLALAELGRRGLLLPSRLV-------------------------------DVVAVILKALTYDEKRGACSVGTNVRDAACYVCWAFARAYEPQELKPFVTAISSALVIAAVFDRDINCRRAASAAFQENVGRQGTFPHGIDILTTADYFAVGNRSNCFLVISVFIAGFPEYTQPMIDHLVTMKISHWDGVIRELAARALHNLAQQAPEFSATQVFPRLLSMTLSPDLHMRHGSILACAEVAYALYKLAAQENRPVTDHLDEQAVQGLKQIHQQLYDRQLYRGLGGQLMR-------QAVCVLIEKLSLSKMPFRGDTVIDGWQWLINDTLRHLHLISSHSRQQMKDAAVSALAALCSEYYMKEPGEADPAIQEELITQYLAELR-NPEEMTRCGFSLALGALPGFLLKGRLQQVLTGLRAVTHTS-PEDVS-------------FAESRRDGLKAIARICQTVGVKA----GAPDEAVCGENVSQIYCALLGCMDDYTTDSRGDVGTWVRKAAMTSLMDLTLLLAR------------SQPELIEAHTCERIMCCVAQQASEKIDRFRAHAASVFLTLLHFDSPPIPHVPHRGELEKLFPRSDVASVNWSAPSQAFPRITQLLGLPTYRYHVLLGLVVSLGGLTESTIRHSTQSLFEYMKGIQSDPQALGS-----FSGTLLQIFEDNLLNERVSVPLLKTLDHVLTHGCFDIFTTEEDHPFAVKLLALCKKEIKNSKDIQKLLSGIAVFCEMVQFPGDVRRQALLQLCLLLCHRFPLIRKTTASQVYETLLTYSDVVGA--DVLDEVVTVLSDTAWDAELAVVREQRNRLCDLLGVPRPQLVPQPGAC---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V1ANP8-1", "uniprot_id": "A0A8V1ANP8_CHICK", "id": "A0A8V1ANP8-1", "name": "Tubulin-specific chaperone D", "aln": "--------MAVGETDGAGSEESGSREADVISRGNILESFTESQEVRALLGNLRTVYGDPVAQEVIVEKFIVIMDKYQEQPHLLDRHLEWMMNMLLDIIR--------DSGSPPVLFHLAFKFLYIITKVRGYKLFLRLFPHEVTDLQPVLDMIVDQNPK---------DCETWETRYMLLLWLSMICLIPFDLARFDGNILSEEG-----------HTRMPTMDRILEIAKCYLVVSDKARDAAAVLVSKFIVRPDVRQKRMADFLDWTLSMLSKSSFQSMEGTVVMNGMLQALAQLFKHGKREDCLPYAATVLECLDNCKLS--ESNQMVLRKLGMKLVQRLGLTFVKPKVAKWRYQRGCRSLAANLQAQSSV------MQSQKITVAANEAEDDEEYDIPGEIENVVEQLLVGLKDKDTIVRWSAAKGIGRITGRLPKELADDVVGSLLDCFSFQETDNAWHGGCLALAELGRRGLLLPSRISDGGLHEVHACCLCVPLINLTRICKVMLLLYLEVVPVILKALTYDEKRGSCSVGSNVRDAACYLSWAFARAYDPSELIPFINQISSALVIAAVFDRDVNCRRAASAAFQENVGRQGTFPHGIDILTAADYFAVGNRVNCYLTISVYIAGFPEYTQPMIDHLVNMKINHWDSVIRELSTKALHNLTPRAPEYMANVVLPRLLPLSVGTDLHTRHGAILACAEITHALCKLAEENNRSITYYFNGKSLEGLKQIHQELCSRQLYRGLGGELMR-------PAVCTLIEKLSLSKMPFKGDPIIEGWQWLINDSLRSLPLASCAARQHVKESAVSALSALCNEYYINENGEADPALQGELVTQYISELQ-STEQMIRCGFSLALGALPRFLLKGRLQQVLEGLRKVTLIT-PRDVS-------------FAESRRDALIAIAEICQTVGVKGE---GSQEEYICKDNVAQIYATLLNCVTDYTTDSRGDVGGWVREAAMTSLMKVTLLLVQ------------NEAELINANICKQIMCWLAQQSAEKIDKFRAHAGSVFLTLLHFDSPPVPHIPHREELERIFPRSEAETLNWNAASEAFPRITQLLALPAYQYYVLLGLSVSVGGLTETTLRYSAQSLFDYMKNIQNDSSAMEG-----FCETLLKVFEDNLRNDRVSVPLLTMLDQMLANGCFDIFTTQGNHPFPVKLLHLCKEEIKRSKDVRKLRSSIGVFCGLIQFQGDMREKVLFQLLLLLCHPFPVIRKTTASQVYEMLITYSEIIDP--AIVDEVMAILSDSNWEAEVAELREKRNRLCDLMKVPKPQLVTKPAGTHTGAHIS--------------------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9VQ78-1", "uniprot_id": "Q9VQ78_DROME", "id": "Q9VQ78-1", "name": "Tubulin-specific chaperone D", "aln": "----------MSNSVEECKDED--------LPANTLEHFTELQQVLEMIDNIKSIAAN--TFEREFEQYAQVLSRYQEQPHLLDPHLEELLGKLLHKIR--------KPDLDTGELHAAFKYLYIICKVRTYKVLVKFMPHELSDLEFVLDLLGQQNPK---------EFEQWETRYILLLWMSILVLNPFHMSRLDAYDTSTSAPTTNCSPVNHVQSKNTKMDRIFELIQLYVSSNDTCSSMAAFLAAKYFIRSDIKDLYLERFLDWIMEQHQADTLN------VKFGQLAAVAAILKHGKREDLLPYADKLLQWITSCQYK--DDNDFLKYKNYVKIIQRIGLVHLKPRIASWRYKRGTRSLATNLNQTTAA------GGEPVVLEQSLEE--GEEIVVPDAIEEVIEELLQALRSGGNDIRWSAAKGLGRVTNRLPKELADEVIGSVIDILNPLEPHEAWHGACLALAELAKRGLLLPHRLE-------------------------------ELVPLLMQALFYDEMKGYMSVGQHIRDSACYMCWAFARAYNPDDVKPFVHKISSGLLTVAVFDREVNCRRAASAAFQESVGRLGNFPFGIEISTTTDFYSVGIRQNSYLNISDYIAQFEVYREPLINHLVQHKVSHWDSAIRELTAKALHKLSLWEPEYMAAVVLPQLLAKTDTIDINCRHGCVLAMGEITLTLRKLEEKSD-PQVVYLSNQRVAELNELIITFLDKNFYRGMSGDLMK-------SCTSSYIKNCSLAKLQATPECLVS-WQKVIDSCL-------ITKSNAIRDGAVEAFGELCTTYYCSDSRHGE---NEAIINTYLTGADNDLEEHIRMGYIAALGVLPSFMIRCHLQAILDSLVKHSLTPLQAVLVGEMGDRENIQAYRWSEARTQSVLALTKLVKTVGYGG-----GIDSFAEPKNFNKVIECLLRALQEYTLDNRGDIGAWVREAAMSSLYEIVTTCP---------------PDLLAPEQVHEIVVGFMQQAVEKIDRTRGLGGRLCCQLIHH-QPRIPYIREHSKLLEIFP-ADADSVLWLFADHTFPLFCELLSLPDYSKRVLLGLSASIGQLTESLIKYASSALFHFLR---SNPETVPR-----LCSEVVQIFEEHLLNERVTYPLLSFLDILIGSGTVESVLHDEANPFAEDIFRLLNLEVKGYKKLYKTATSISAFCQLLQVP-RLSKRILSKLSVFLGLQHVHVRKTAATKLYEALALHGDVTEVPEENMDEILTLLSETDWTQPLVEVRPLRNQLCQLMDIKPPVSGAAAAAALQQASADK-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8L5R3-1", "uniprot_id": "TBCD_ARATH", "id": "Q8L5R3-1", "name": "Tubulin-folding cofactor D", "aln": "MASRAEEMSPTKIEIETAVKIEEEEDDEHDSKERVLQRYFLQEWKLVKSLLDDIVSNGRVVDPTSVHKIRSIMDKYQEQGQLVEPYLESIVSPLMFIIRSKTVDLEAKPDEILEIIKPISIIIYALVTVCGYKAVIKFFPHQVSDLELAVLLLEKCHSTNSVSALRQESTGEMEAKCVTLLWLSILVLVPFDISSVDTSIADDKTFG--------VDDLAPLVLKILGFCKDYLCSAGPMRRISGLLLSKLLTRPDMG-KAFSSFFEWTYEVLS-CKEDSVTNHFRLLGVMEALSAIFKTASRKVLLDVLPIVLNDVTVLSKSNAAAKSSLLRKYLIKLTQRIGLVCLPHRSPSWRYVAQTASLSENMSTSSSQRLAPDHTVTAILQPESLDDQEDEDMDVPEILEEIIEMLLSGLRDTDTVVRWSAAKGIGRVTSRLTSVLSDEVLSSVLELFSPGEGDGSWHGGCLALAELARRGLLLPRSFP-------------------------------LVVPVIVKALHYDVRRGPHSVGSHVRDAAAYVCWAFGRAYSHKDMKNVLDQLAPDLLIVGSFDREVNCRRAAAAAFQENVGRQGNYPHGIDIVSIADYFSLSSRVNSYLQVAVSIAQYEGYLYPFVDELLYNKICHWDKSLRELAAEALAPLVKYEPKHFANYVLEKLIPCTLSTDLCMRHGATLAAGEVVLALHQCG--------YVLSADSQKRMAGIVPSIEKARLYRGKGGEIMR-------LAVSRFIECISLSHVTLAERTERILLDTLTENLR--------HPNSQIQNAAVSAVKQLVQSYLVGNDKKSVD-----LILKHLKHLT-DPNVAVRRGSALALGVLPYELLTAKWKDIVLKLCSACKIEVNPEDR-------------DAEARVNAVKGLTSVCETLTQKRASDPGNDDLSLFLLIKTEVMDTLLKALDDYSVDNRGDVGSWVREAAVHGLEKCTYILCKKMETYSEGDYNDDTSSLFDSNLATRLIGGMLKQGVEKMDKLRETAAKVLQRILYHKSVSVPHVPYREKLEEILP--NKANLQWAVPAFSFPRFVQLLKLRCYSKEVMSGLVISIGGLQDSLRKASLVALLEYMREGEAKDPKEQQSRESALGDDILWILQEYKKCDRVMVPCLQTIEILFSS-KIFLNQESYTFSFYAGVMDSLAIELRASKDFTKLKAGLAILGYIASVSHFISTKAFSQLLSFLGHRYPMIRKAAAEQVYLALLQNGILVTE--EKMEKVIEIISESCWEADMETTKTQRLELCELAGLDHEVVFKTRNRLVIKDIAGNKSAADENASYSSLVDSSGF", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *: : : .: ::.:**** :*:: :** ::. *: :: . .: :* : .* ** .::::**:::::: .: :. :.. . *:: : ***:*: * **.:: .* . . : :*: : : *: . :..* :: : *.*: : *::* . : * : *:: ::* ..*: * :*. : . * :*: **:**. : : . *** **: *:. : .*: :* :* ::* ** .*:. .. :*******:**::.**. *:*:*:.*::: :. * . :***.*******.:****** : :*.::::** ** :* *** ::**:*.*:.***.***. .:: .: ::. *: .. ***::******:*****.*** *.:*.**:* : :*::::. *.:* :: ** : * *:::.*: *: *** :***::.** * *:. * *: *: : *: ***. ** .*:. :* : :. . : : . *:. *.:* .. *: **::: : : :. . ::. . . : :: :: . : * * ***.** :: : : :: * :*:* :.: .:: : :*: : :: ** .: :*: *.***:* ***:*:: .* . . *: .. .:: . :*. **:*: * .. : :::. . :*:: : :* ::* : .: * . :** : :** * * *: ** *:* * :: : : :*:.::: . : :: :::: :** . * :: :: . . .* :: *:: *.. * :.:. : : .. : : : :* :* . :**::* ::* : . : ::::: ::*:: * : : * .**:* : ", "identical_positions": 232, "similar_positions": 369, "identity": "17.29%" }, { "cls_id": "homologset.oma.815908", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BTG3-1", "uniprot_id": "T11L1_MOUSE", "id": "Q8BTG3-1", "name": "T-complex protein 11-like protein 1", "aln": "MSENLDKSHVDEAGEAEAAASEQGLEGALECSDETLQKKVKSDSPSSQRVGRPHSSPARLVTVEELLETAKGVTNMALAHEIVVTGDFRINAVELAEGSLEKRVKEIVHKAFWDCLSVQLSEEPPTYDHAIKLVGEIKETLLSFLLPGHTRLRNQITEVLDLELIKQEAENGALDISKLAEFIIGMMGILCAPARDEEVKKLKGIKEIVPLFRAIFSVLDLMKVDMANFAISSIRPHLMQQSVEYERRKFQEVLERQPNSLDFATQWLEEATNDLLSQKYKHALPAGGGAAGSGDAPLLTPVSVQNFAYLKLLKWDHFQRPFPETVLMDQSRFQELQLQLEQLAVLGAVLLVTFSTAAPGISGHADFAEKLKMMVKTLLTDMHLPSFHLEDALASIGEKVCLEVSSCLSLCGSSPFSVAKETVLKGQIQALASPEDPIRRIMESRIFTFLETYLASGHQKPLPTVPGGLGPIQKELEEVAVKFVRLVNYNKMVFCPYYDAILSKLLLRS----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K6F1-1", "uniprot_id": "A0A0G2K6F1_RAT", "id": "A0A0G2K6F1-1", "name": "", "aln": "MSENLDKSHVNEAGESKSAASEEGQKGALECSDEALQEKVKSDSPSPLRVGRPHSSPPRLVTVEELLETAKGVTNMALAHEIVVNGDFRINAVELAEGSLEKRVKEIVHKAFWDCLSVQLSEDPPTYDHAIKLVGEIKETLLSFLLPGHTRLRNQITETLDLELIKQEAENGALDISKLAEFIVGMMGILCAPARDEEVKKLKDVKEIVPLFRAIFSVLDLMKVDMANFAISSIRPHLMQQSVEYERKKFQEVLEKQPNSLDFVTQWLEEASNDLLTQKCKHALPAGGGAAGSGDAPLLTAASVQNYAYLKLLKWDHFRRPFPETVLMDQPRFQELQLQLEQLALLGAVLLVTFSTSAPAVSGHAGFAEKLKTVVKILLADVHLPSFQLEDALTSIGEKVCLEVSSCLSMCGSSPFSVSKETVLKGQIQALASPDDPIRRIMESRILTFLETYLASGHQKLLPTVPGGLGPIQKELEEVAVKFVRLVNYNKMVFCPYYDEILSKLLLRS----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8C2L9T4-1", "uniprot_id": "A0A8C2L9T4_CRIGR", "id": "A0A8C2L9T4-1", "name": "", "aln": "MSENLDKSHINEAGESKPSDSEQGLEGALECSDEALQKKIKSDSPSPQRVGRPHSSPARLVTVEELLETAKGVTNMALAHEIVVNGDFRIKAVELAEGSLEKRVKEIVHKAFWDCLSVQLSEDPPTYDHAIKLVGEIKETLLSFLLPGHTRLRDQITEVLDLELIKQEAENGALDISKLAEFIIGMMGTLCAPARDEEVKKLKDIKEIVPLFRAIFSVLDLMKVDMANFAISSIRPHLMQQSVEYERKKFQEVLEKQPNSLDFVTQWLEEASNDLLTQKYKHTLPAGGGAAGSGDAPVLTPVSVQNYAYLRLLKWDHFRRPFPETVLMDQSRFQELQLQLEQLAILGAVLLVTLSSATPGISGRADFAEKLKMTVKILLMDMHLPSFHLEDALTSIGEKVCLEVSSCLSLCGSSPFSINKETVLKGQIQALASPDDPIRRIVESRIFTFLETYLASGHQKLLATVPGGLGPIQKELEEVAVKFVRLVNYNKMVFCPYYDAILSKLLLRS----------------------", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "A0A3Q1LT06-1", "uniprot_id": "A0A3Q1LT06_BOVIN", "id": "A0A3Q1LT06-1", "name": "", "aln": "MSENLDKSNINEAGKSKSSDSEQGLEDAVEVSDEALQKKIKSGSPSTQRVQRPHSSPPRFVTVEELLETAKGVTNMALAHEIVINGDFQIKPVELPEDSLEKRVKDIVHKAFWDCLSVQLSEVPPTYDRAIKLVGEIKETLLSFLLPGHTRLRNQITEVLDLDLIKQEAENGALDISKLAEFIIGMMGTLCAPVRDEEVKKLKDIKEIVPLFRAIFSVLDLMKVDMANFAVSSIRPHLMQQSIEYERKQFQEFLEKQPNSLDFVTQWLQEATDDLMSQKYKNALPAAGGAAGSGDGPQLDPVAVQNYAYLKLLKWDHLHRPFPETVLMDHSRFQEFQLQLEQLTVLGAVLLVTFSMAAPGIASRADFAEKLKMIVKILLTDMHLPSFHLEDALTAVGEKVCLEVSSCLSLCGLSPLTTDKEAVLKGQIQAVASPDNPIRRIVDSRILTFLDAYLASSHQKPSPIAPGGLGPIQKELEEVAVKFVRLVNYNKMVFSPYYDAILSKTLARS----------------------", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "I3L8N0-1", "uniprot_id": "I3L8N0_PIG", "id": "I3L8N0-1", "name": "", "aln": "MSENLDKSNINEAGKSKSNDSEQGLEDAVEGSDEALQKKIKSGSPSTQRVQRPHSSPPRFVTVEELLETAKGVTNMALAHEIVVNGDFRIKPVELPEDSLEKRVKDIVHKAFWDCLSVQLSEDPPTYDRAIKLVGEIKETLLSFLLPGHTRLRNQITEVLDLDLIKQEAENGALDISKLAEFIIGMMGTLCAPVRDEEVKKLKDIKEIVPLFRAIFSVLDMMKVDMANFAVSSIRPHLMQQSVEYERKQFQELLEKQPNSLDFVTQWLEEAADDLMNQRYRNALPAGGGAAGSEASPRPDPAAVQNYAYLKLLKWDHLHRLFPETVLMDRSRFQELQLQLEQLTVLGAVLLVTFSMAAPGISSRADFAEKLKMIVKILLTDMHQPSFHLEDALTAVGEKVCLEVSSCLSQCGFSPLTPDKEAVLKGQIQAVASPDNPIRRIMDSRILTFLETHLASSHQKPLPTAPGGLGPVQKELEEVAVKFVRLVNYNKMVFSPYYDAILSKILATS----------------------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q9NUJ3-1", "uniprot_id": "T11L1_HUMAN", "id": "Q9NUJ3-1", "name": "T-complex protein 11-like protein 1", "aln": "MSENLDKSNVNEAGKSKSNDSEEGLEDAVEGADEALQKAIKSDSSSPQRVQRPHSSPPRFVTVEELLETARGVTNMALAHEIVVNGDFQIKPVELPENSLKKRVKEIVHKAFWDCLSVQLSEDPPAYDHAIKLVGEIKETLLSFLLPGHTRLRNQITEVLDLDLIKQEAENGALDISKLAEFIIGMMGTLCAPARDEEVKKLKDIKEIVPLFREIFSVLDLMKVDMANFAISSIRPHLMQQSVEYERKKFQEILERQPNSLDFVTQWLEEASEDLMTQKYKHALPVGGMAAGSGDMPRLSPVAVQNYAYLKLLKWDHLQRPFPETVLMDQSRFHELQLQLEQLTILGAVLLVTFSMAAPGISSQADFAEKLKMIVKILLTDMHLPSFHLKDVLTTIGEKVCLEVSSCLSLCGSSPFTTDKETVLKGQIQAVASPDDPIRRIMESRILTFLETYLASGHQKPLPTVPGGLSPVQRELEEVAIKFARLVNYNKMVFCPYYDAILSKILVRS----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W461-1", "uniprot_id": "Q9W461_DROME", "id": "Q9W461-1", "name": "T-complex protein 11-like protein 1", "aln": "MDAQENRSEQSGQSGDHEEHEERRIRTDSESSVESMTRFVLPSLDG---------TPPKIVTLDEVSSMFKNLRNMELAHEIALNPDFKLQKYEPPSDSLEGAIKKMVHKAFWDLLRVQLDRQPPSYDQAIRLLAEIKECFPQLLSPNNERALAHINEVLDDSVIRQQAERGTLDFRAYANFVINILSRSCSPARDEAVAALRKIDDVVDTFRCILELMTLMKLDMANFMLRLARTEIAANSVQYEKEKFSKYLREFHGNVGFP------ATEDWLQRHR---------SGSSDDETIYN-------AYMQLIDYP-ADKEFPELLRIDKERFAGLSWRAQRLILC--ASLISVAQGMPIISQRRENRIKLAQQLDIIVQDIKN-QDQVASTIESCYEQIRSFVNKALEQENLPALSDADQAALKNQVLKLANKTSPVPSLMAKRLDGYVRVTLRS--NGSIPPPPSGFADYQEELVAFIASFRRLVSYNHAVFGEHFHQILNKTLPGEETEATTSTASGINPGQAQTAKP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : ::*. . . . .*. . * : *:: . : .. . :*.::**::*: . :.: ** *****.:. **::: * ...**: :*.:******* * ***.. **:**:**:*:.**** : .:* *.: * :*.*.** .:*:*:**.*:**: *:*::.::. *:*.*** * *: :.::* ** *:.:: :**:***** : *..: :*::**:.:*.: *.. ..:.* *::* : :: :..* . **::*:.: : *** : :*: ** :. : ::* : . *::.: . * :: : ** :. :: *:: . :: ..: : *:: *...*. . ..:: .::.**.*: :*. .*: :: .*: :: . * * : . *.*:. *.** . .* ***.**: ** ::. **.* * . ", "identical_positions": 131, "similar_positions": 192, "identity": "24.67%" }, { "cls_id": "homologset.oma.815909", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B4DZS4-1", "uniprot_id": "T11X1_HUMAN", "id": "B4DZS4-1", "name": "T-complex protein 11-like X-linked protein 1", "aln": "--------------------------------------MPKTEETVLQNDPSVAENGAPEPKTPGQSQKSKS---FCLDDQSPDLIET-----VNEVSKLSISHEIVVNQDFYVEETILPPNSVEGRFAEAMYNAFWNHLKEQLLSTPPDFTCALELLKDVKETLLSLLLPWQNRLRNEIEEALDTDLLKQEAEHGALDVPHLSNYILNLMALLCAPVRDEAIQKLETIRDPVQLLRGILRVLGLMKMDMVNYTIQSFRPYLQEHSIQYEQAKFQELLDKQPSLLDYTTKWLTKAATDITTLCPSSPDSPSSSCSMVCSLPSGAGNNSEPPSPTMVLYQGYLNLLLWDLENVEFPETLLMDRIRLQELAFQLHQLTVLASVLLVARSFSGEVLFRSPEFVDRLKCTTKALTEEFISRPEETMLSVSEQVSQEVHQGLKDMGLTTLSSENTASLLGQLQNITKKENCIRSIVDQWIRFFLKCCLLHGMQESLLHFPGGLILIEKELAELGWKFLNLMHHNQQVFGPYYAEILKHIIHPAQAQETDVEPN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1M6M6-1", "uniprot_id": "F1M6M6_RAT", "id": "F1M6M6-1", "name": "", "aln": "MVYSMDSSTGEPQGFSVVRAATTGKGSQTPRTRRDTTNMPKTKKNISQKDSSPTEIRVPKPETSTKNQEDKTSSEVPFPENQPAAISKEDLGKVNEVSKLSIAHEIVVNQDFIVEKNDLPENSLESKFVETMYNAFWDHLKDQLSRTPPDFSCALELIKNIKQILMSLLLPRQNRLRNEIEEALDLDLLKQETEHGALDVPHLSNYILNLMALMCAPVRDEAVQELESIKDPVQLLRGIFQVLGLMKMDMVNYTIKNIRPYLQEHSIQYERAKFQELLDKQPDLLDCTTKWMTRAATELITSLPSISVSPSTSSGTISAFPS-PKPDPDPPSLTTVLYQGYLNLVLRDHGSEEFPETLLMDKARLQNMKSKLRHLTILASVLLVARSFSCGVLFSSPEFVDKLKCITKALTEEFSSKPEESMLSVSEQVSQEIHQGLKETGLTALSSENRASLVGQLRNIAKKENCIRTIIEQRIHLFLKCCLIRGMQESLLDFPGGLLFIEPELAELGWKFVNLMHHNQHVFSPYYAEILKNIISPPSTEENEEKPF", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 347, "similar_positions": 107, "identity": "63.32%" }, { "cls_id": "homologset.oma.815912", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8WWU5-1", "uniprot_id": "TCP11_HUMAN", "id": "Q8WWU5-1", "name": "T-complex protein 11 homolog", "aln": "MPDVKESVPPKYPGDSEGRSCKP------ETSGPPQED-------------------------------------KSGSEDPPPFLSVTGLTETVNEVSKLSNKIG----------------------MNCDYYMEEKVLPPSSLEGKVKETVHNAFWDHLKEQLSATPPDFSCALELLKEIKEILLSLLLPRQNRLRIEIEEALDMDLLKQEAEHGALKVLYLSKYVLNMMALLCAPVRDEAVQKLENITDPVWLLRGIFQVLGRMKMDMVNYTIQSLQPHLQEHSIQYERAKFQELLNKQPSLLNHTTKWLTQAAGDLTMSPPTCPDTSDSSSVAGPSPNEAANNPEPLSPTMVLCQGFLNLLLWDLENEEFPETLLMDRTRLQELKSQLHQLTVMASVLLVASSFSGSVLFGSPQFVDKLKRITKSLLEDFHSRPEE-AILTVSEQVSQEIHQSLKNMGLVALSSDNTASLMGQLQNIAKKENCVCSVIDQRIHLFLKCCLVLGVQRSLLDLPGGLTLIEAELAELGQKFVNLTHHNQQVFGPYYTEILKTLISPAQALETKVESV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A5G2QC67-1", "uniprot_id": "A0A5G2QC67_PIG", "id": "A0A5G2QC67-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------MNRDFHTEEKVLPPSSLEGKVKETMHNAFWDHLKEQLLATPPDFSCALELLKEIKEILLSLLLPRQNRLRSEIEEALDVNLLGRAAEQGALNVPHVSKYILNTMTLLCAPVRDEAVQKLETISDPVRLLRGIFQVLGLMKMDMVNYTIQSLQPQLQEHNIQCERARFQELLNKQPSLLDHTTRWLTQAATDLATPPPPCPDTPDSSSATCLPAGEAAISPEPLSPKMVLSQGFLNLLLWDGEDEAFPETLRTDRARLQELEAQLHRLTVLASVLLVANSFSGSVLFGSPQFVDKLKRTTKVLLEEFGSRPEEEAMLTVSEQVTQEIHQSLKNMGLAPLSSDNTASLIGQLQNIAKKENCVRSVIDQRIHLFLKCCLILGVQRSLLDLPGGLTLIEAELAELGQKFANLTQHNQQVFGPYYTEILKTLIPPAQVLETEMESL", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q5XI00-1", "uniprot_id": "TCP11_RAT", "id": "Q5XI00-1", "name": "T-complex protein 11 homolog", "aln": "MPDLKERAARKEPGAAESASRESRGGNTRESASSAQGHRSRRFNRRSSTAALTPGSAQGRGVQTAPRAPVGHGGLRTGLTSRCPQPSARAKLPSVTRGAPLPPSPGKGHFGATPISHRLGLTERVHDASKLDCHLEDR-KSASSLESRGKEVMPSDFWDHLKEQLSAVPPDFSCALELLKEIKEILLSLLLPRQSRLRNEIEEALDMEFLHQQADRGDLNVSYLSKYILNMMVLLCAPVRDEAVQRLENISDPVRLLRGIFQVLGQMKMDMVNYTIQSLQPQLQEHSIQFERAQFQERLNKDPSLLNHTTKWLTQAATQLIAPSGSCYDIQDPSSSSGPSPSDIAI-PEPLSPAMVLSQGFLNLLTWDPENEEFPETLLADRSRLQELESQQNQLTILASVLLVASSFSGSVLFGSPQFVDRLKRITKSLVEDFNSRPEE-VMQTVSDQVTEEIHQSLKNMGLSPLSSENTDSLIGQLQNIAKKENCVRSVIDQRIHLFLKCCFVLGVQRSLLDLPGGLSLIEAELAELGQKFVSLTHHNQQVFAPYYTEILKTLINPVQTLTTKVGSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01755-1", "uniprot_id": "TCP11_MOUSE", "id": "Q01755-1", "name": "T-complex protein 11", "aln": "MPDVKERAARKEPGAAESASRESRGGNTRESASSARGT-DRVGSTVARARPPSPQGPRRGAVKTAPRGPVGHGGLRTGPTSRCPQPSARAKLPSVTRGAPLPPSPGKGHLGGTPSSHRLGMTERVHDASKLDCQLEERSLSSSSLKGKVKDTMPSDFWEHLNEQLSAVPPDFSCALELLKEIKEILLSLLLPRQSRLKNEIEEALDMEFLQQQADRGDLNVSYLSKYILNMMVLLCAPIRDEAVQRLENISDPVRLLRGIFQVLGQMKMDMVNYTIQSLQPQLQEHSVQFERAQFQERLNKEPRLLNHTTKWLTQAATQLIAPSASSSDLQDCSSSAGPSPSDVAV-PEPLSPAMVLSQGFLNLLTWDPENEEFPETLVADRPRLQELESQQSQLTILASVLLVASSFSDSGLFSSPQFVDKLKQITKSLVEDFNSRPEE-VMQSVSEQVVEEVHQGLESMGLAALSSENTASLVGQLQNIAKKENCVRSVIDQRIHLFLKCCFVLGVQRSLLDLPGGLTLIEAELAELGQKFVSLTHHNQQVFAPYYTEILKTLISPAQTLATKGGSL", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * *:: ..***:.: *:.: . **:**:*** *.**************************.**: *******:::* : *::* *:* ::***:** *.*****:******:**.*:*** ********** ***************:****.:* ***:*** ***:* **:***:****** :* .. .. * * ** : ...: * ****** ***.******* ** *:* ***** **.*****::* :**::*******.***.* **.******:**: ** *:*:* ***** .: :**:** :*:**.*:.*** .***:** **:************* **************::**************:*************..**:******.*********** *.*.* *: *:", "identical_positions": 296, "similar_positions": 87, "identity": "52.02%" }, { "cls_id": "homologset.oma.815913", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K1H7-1", "uniprot_id": "T11L2_MOUSE", "id": "Q8K1H7-1", "name": "T-complex protein 11-like protein 2", "aln": "MPFNGEK------QCVSEDQQSDSESSRFAEGVASLSDYECSRQSFTSDSSSKSSSPASTSPPRGLMFDDVMAAAKNLSDMTLAHEIAVNENFQLKQNALPENSLAGQVKRVVHQAFWDVLEADLSAEPPQYEYAIKLFEEIREILLSFLTPGGNRLHSQICEVLDIDLIRQQAEHSAVDIQGLANYVITTMGKICAPVRDEDIRELKATT-NIVEMLRQIFRVLDLMRMDMMNFVIRNIRPHIQHHLVEYERNKFQEVVEETPNALSQTTEWLKESIDKELL--SETDVAPAAEHSSTPSLSPLLVLNNCYLKLLQWDYQKKVLPETLMTDGPRLQELSEKLNQLKMTACVALITNNMVGAVTEGLPELANRLKRISAVLLEGMNKETFNLKEALHSIGVQTCAEVNKALEERGSPTLNAEVQANLVGQLSSLEEKDNPVCTLMDKRIQLYMKGLLCLPSTQKSMPPVPGGLDVIQRELEVLGCQYANIVNLNKQVYGPFYANIFRKLLFRDEAVGKIDASLPTN-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q568Z0-1", "uniprot_id": "T11L2_RAT", "id": "Q568Z0-1", "name": "T-complex protein 11-like protein 2", "aln": "MPFNGEK------QYVNEDQQSDSESSRFSESTASLSDYGCSRQSFTSDSSSKSSSPASTSPPRGIMFDDVMAAAKNLSDMTLAHEIAVNENFQLRPNALPENSLAGQVKRVVHQAFWDVLEADLSAEPPQYEYAIKLFEEIREILLSFLTPGGNRLHSQICEVLDIDLIRQQAEHSAVDIQGLANYVISTMGKICAPVRDEDIRELKATT-NIVEMLRQIFRVLDLMRMDMTNFVIRNIRPHIQHHLVEYERNKFQEVLEETPNALSQTTEWLKESIDKELF--SETDVAPGAEHSSTPSLSPLTVLNNCYLKLLQWDYQKNVLPETLMTDGPRLQELTEKLNQLKMIACVSLITNNMVGAVTEGLPELANRLKRISAVLLEGMSKQTFNLKEALNSIGVQTCAEVNKALKERGSPTLNAEVQANLVGQFTSLEEKDNPVCALMDKRIQLYMKSLLCLPSTQKSRPPVPGGLDVIQQELEVLGCQYANIVNLNKQVYGPFYANIFRKLLFRDEAMGKIDASLPTN-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A7Z033-1", "uniprot_id": "T11L2_BOVIN", "id": "A7Z033-1", "name": "T-complex protein 11-like protein 2", "aln": "MPFNGEK------QCVSEDQPSDSDSSRFSESMASLSDYECSRQSFTSDSSSKSSSPASTSPPRVVTFDEVMAAARNLSNMTLAHEIAVNENFQLKQDALPESSLAGRVRHIVHQAFWDVLESELNAEPPEYEHAIKLFEEIREILLSFLTPGGNRLRNQICEVLDTDLIRQQAEHSAVDIQGLANYVISTMGKLCAPVRDDDIRELKATS-NIVEVLRQIFHVLDLMKMDMVNFTIRSLRPHLQRQLVDYERTKFQEILEETPSALNQTTEWIKESVHEELLSLSEATLTPGAENNSKPSLSPTLVLNNSYLKLLQWDYQKKELPETLMTDGARLQELTEKLNQLKMIACLALITNNMVGALTEGLPELAVRLKRISAVLLEGMNKETFNLKEVLNSIGIQICVEVNKTLMERGLPTLNAEVQDNLVGQFSSIEEEDNPIWSLIDKRIQLYMKSLLCLPSPPRCMPPVPGGLAVVQQELESLGLQYANIVNLNKQVYGPFYANILRKLLFGEEATGKAEASSSTN-----", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1SPQ0-1", "uniprot_id": "F1SPQ0_PIG", "id": "F1SPQ0-1", "name": "", "aln": "MPFNGEK------HCVGEDQPSDSDSSRFSESMASLSDYECSRQSFTSDSSSKSSSPASTSPPRVVTFDEVMAAARNLSNMTLAHEIAVNENFQLKQDALPENSLAGRVRHIVHQAFWDVLESELNAEPPEYEHAIKLFEEIREILLSFLTPGGNRLRNQICEVLDTDLIRQQAEHSAVDIQGLANYVISTMGKLCAPVRDDDIRELKATG-NIVEVLRQIFHVLDLMKMDMVNFTIRSLRPHLQRQLVDYERTKFQEILEETPSALDQTTEWIKESVHEELLSLSEAALTPGAENSSKPSLSPTLVLNNSYLKLLQWDYQKKELPETLMTDGARLQELTEKLNQLKMIACLSLITNNMVGALTEGLPELAIKLKRISAVLLEGMNKETFNLKEVLNSIGIQTCVEVNKTLMERGLPALNAEVQANLVGQFSSIEEEDNPVWSLIDKRIQLYMKSLLCLPSPQKCMPPVPGGLTVIQQELEVLGSQYANIVNLNKQVYGPFYANILRKLLFSEEATGKADASSSTN-----", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q8N4U5-1", "uniprot_id": "T11L2_HUMAN", "id": "Q8N4U5-1", "name": "T-complex protein 11-like protein 2", "aln": "MPFNGEK------QCVGEDQPSDSDSSRFSESMASLSDYECSRQSFASDSSSKSSSPASTSPPRVVTFDEVMATARNLSNLTLAHEIAVNENFQLKQEALPEKSLAGRVKHIVHQAFWDVLDSELNADPPEFEHAIKLFEEIREILLSFLTPGGNRLRNQICEVLDTDLIRQQAEHSAVDIQGLANYVISTMGKLCAPVRDNDIRELKATG-NIVEVLRQIFHVLDLMQMDMANFTIMSLRPHLQRQLVEYERTKFQEILEETPSALDQTTEWIKESVNEELFSLSESALTPGAENTSKPSLSPTLVLNNSYLKLLQWDYQKKELPETLMTDGARLQELTEKLNQLKIIACLSLITNNMVGAITGGLPELASRLTRISAVLLEGMNKETFNLKEVLNSIGIQTCVEVNKTLMERGLPTLNAEIQANLIGQFSSIEEEDNPIWSLIDKRIKLYMRRLLCLPSPQKCMPPMPGGLAVIQQELEALGSQYANIVNLNKQVYGPFYANILRKLLFNEEAMGKVDASPPTN-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RGW3-1", "uniprot_id": "Q5RGW3_DANRE", "id": "Q5RGW3-1", "name": "", "aln": "MPLNDERPTSTSSTVASEDQSSDTESSERCDSLTSSSDVDCSRQSFTSDSSSKHNSPS-CSPPKILTLDEVMASARDLSNLSLAHEIVVNRNFHLEPPDLPQNSLEKRVKDMVHKAFWDCLESELNDDPPEYDYAIKLLEEIRDTLLSFLNPGANRLRTQIMEVLDMDLIRQQADNNAVDIQGLVSYIINTMGKFCAPVRDDEIKKLKENSGDCVTLFKEIFRVLDLMKMDMVNFTIQSFRPELQRQSVEYERAKFQSILERTPNALEHTTEWIKSSIEEATQIMPPAEKSSDSGQSGRPLPGPSLVLNTAYIKLLTWDDSKGPLPETVMTDEARLQVMQRSLQLYQTVASVLLIVYSSIGGAVSGLPALAERLKKMTVVLLEGMHNTEFKLNEALGNVSVQICCEVNKSLAERNFPALPDELQATLKGQICDVTQENNPVRTLVEGRVQQYLWVVLSSSSSHRTPPPVPPGLTLIQQELMPLSLSFANLVNFNKKVYGPFYFSILKSLLFSDTQN-HIPPGPPSSPLKSK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*.*: ..*** **::**. .:. :* ** ******:****** .**: ***: : :*:***:*::**:::*****.**.**:*. **:.** :*: :**:**** *:::*. :**::::****:****: *****.**.***:.** **** *******::.*******..*:*.****:******::*::** . : * ::::**:*****:*** **.* .:**.:*:: *:*** ***.::*.**.**.:****:*.*:.: . : :. : :.. * .* ***..*:*** ** .* ****:*** .*** : ..*: : *.: **. . :*. . *** ** :*.:::.****** : *:*:*.* .:.:* * ****:* **. *:* *:* .* **: .: :::**: :*:: *:: *: :*. .*. : **:* ** ::*:** *. .:**:**:**:****** .*::.*** : : .. .:. ", "identical_positions": 242, "similar_positions": 175, "identity": "45.57%" }, { "cls_id": "homologset.oma.815915", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5H9J9-1", "uniprot_id": "T11X2_HUMAN", "id": "Q5H9J9-1", "name": "T-complex protein 11-like X-linked protein 2", "aln": "MPKTEETVLQNDPSVAENGAPEPKTPGQSQKSKSFCLDDQSP----------DLIETVNEVSKLSISHEIVVNQDFYVEETILPPNSVEGRFAEAMYNAFWNHLKEQLLSTPPDFTCALELLKDVKETLLSLLLPWQNRLRNEIEEALDTDLLKQEAEHGALDVPHLSNYILNLMALLCAPVRDEAIQKLETIRDPVQLLRGILRVLGLMKMDMVNYTIQSFRPYLQEHSIQYEQAKFQELLDKQPSLLDYTTKWLTKAATDITTLCPSSPDSPSSSCSMACSLPSGAGNNSEPPSPTMVLYQGYLNLLLWDLENVEFPETLLMDRIRLQELAFQLHQLTVLASVLLVARSFSGEVLFRSPEFVDRLKCTTKALTEEFISRPEETMLSVSEQVSQEVHQGLKDMGLTTLSSENTASLLGQLQNITKKENCIRSIVDQWIRFFLKCCLLHGMQESLLHFPGGLILIEKELAELGWKFLNLMHHNQQVFGPYYAEILKHIIHPAQAQETDVEPN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G5E5P7-1", "uniprot_id": "G5E5P7_BOVIN", "id": "G5E5P7-1", "name": "T-complex 11 family, X-linked 2", "aln": "MPKMEKTVHQNDSNEAESGAHKPETPEQTQENQSFCLDDHSAASRPEVLSVTDLIETVNEISRLSIAHEIVVNQDFYMEDGVLPPNSLEGRIMETMYKAFWDHLKVQLSSTPADFTSALELLKEVKEILLSLLLPRQNSLRDEIEEALDIDLLKQEAEHGALDVPHLSNYILNLMTLLCAPVRDEAVRKLESITDPVQLLRGIFHVLGLMKMDMVNHTIQSFRPYLKEHSIQYERAKFQELLNKQPNLLDCTTKWLTKTALDLTTAPSSSPDSPSSS-SMAHSSPNWAVDNPQLPSSTMVLYQGYLNLLLWDLDSKEFPETLLMDKIRLQDMESQLKQLAILASVLLVARSFSGSALFSSTEFVNKLKHITKALMEEFNSRPEEAMVSVSEQVSQKIHERLKDMGLTALSSEKKACLRGQLQNIAKKENRVRNIVDQRIHLFLKGCLVRGMQESLLDFPVGLTLIKGELTKLGWKFFNLMRHNQQVFSPYYDEILKDIIPPAQAQETEVESI-", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A2AEI7-1", "uniprot_id": "A2AEI7_MOUSE", "id": "A2AEI7-1", "name": "", "aln": "MPKSEKIISKKDSSPSENGSPKPETSSKNQEDK-TSSEVHSAENQLAAIS-NEDTGKVNEVSKLNVASEIAI------EKNDLPEDSPESQFVETMYNAFWDHLRDQLSQTPPDFSCVLELIKNIKQILMALLLPRQNLLRNEIEEVLDLDLLKQETEHGALDILHLSHYILNLMALMCAPIRDEAVKELENIKDPVQLLRGIFQVLGLMKMDMVNYTIKNIRPYLQEHSIQYERAKFQELLDKQPDRLDCTTKWMTRAATEIITSLSSLSVTSCISSGVISSFPTPKPD-PDPPSLTTVLYQGYLNLVLRDHGNEEFPETLLMDKARLQTMRSKFRHLTILASVLLVARSFSCGVLFSSPEFVDKLKCITKALTEDFSSKPEESMLSVSEQVSQEIHQGLKDTGLTALSSENRASLVGQLRNIAKKENCIRIIIEQRMHLFLKCCLIRGMQESLLDFPGCFLFIEPELAELGWKFVNLMHHNQHVFSPYYAEILKNIIS-TQNDEDEEKPIK", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *: : ::*.. :*.*: :*:*. :.*:.: . : :*. : .***:*:*.:: **.: *. ** :* *.:: *:**:***:**: ** .**.**:..***:*::*: *::**** ** **:****.** ******:******: ***:******:*:***:****:::**.* *********::***********:**:.:****:*******:*******:***. ** ****:*::* :: * .* . :.. * .: * *. : .: ** * *********:* * . *********: *** : ::::*::************ .** *.***::** **** *:* *:***:*:********::*: *** ***:****: *.* ***:**:**** :* *::* :::*** **::*******.** : :*: **::*****.***:***:**.*** ****.** :* :* : :. ", "identical_positions": 277, "similar_positions": 138, "identity": "54.0%" }, { "cls_id": "homologset.oma.815953", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1M632-1", "uniprot_id": "F1M632_RAT", "id": "F1M632-1", "name": "Adenylate kinase 9", "aln": "MASEEKTEE-HPFADIFNEDETDRNCLLSKPACFIIFGKPGVGKTTLARSIAQAWKCIRVEAISVLEEHIAAENETGTMLQSLLVSGHTVPDELVTKLVLEKIKSPEVSHFGYILTEIPSLSQDNMTSLKQIEIIKHLELQPDVIINIKCSDYDLCQRISGQRQHSTTGYIYTREQWDPEIIESRRKKKKEVLKEGKAEEEEEEEQEEEEEAFLAEMQMVTETLQYLVQRPEDYLENIEVTVNLYKELLLNALEEVMAEHNPQYLIELDGNKPPEELFLTVIERLKYLNVRRAAIITKLQGTEE-EMTDIIDTEELFRTVSSYKLMGPRYRWNRSKWARACPVSLKDGNIYPGAADFSVSFLGKMYCLSSEETLKLFLLNPRPFLLPPMPLPPCKVFIFGPNHSGKTTLANLIAEHFKAKVIDYATLVQPRFDSAREKLIKDTISEATNTAIKLVKERLLNDLRVKKQEEKTLKELRMHYTKKEYEDFSDYKKTKSSEEFPSSADDPEAQGSRNLSALEIGPEDKSRSENTISGDTDKD-------------------------------GSPEELIEEVTENHPEVFAMIEDTLRHSKELNFEQPYDKQAEILEEVIKEVTKDNKNRFAGAPKYGGWIVKNFPIMRELWMSLIEKA--LLPDLVVNLSDTESNGKIVLTRLYLSNKAEINAKILERLKEELQVKKREEDEIRKVKEEELRLEEEKQRMMELEAKKAK-------------VVEEPDN-EAEEEVDVEESEIHEETEAQEMGELARESSIPGGSESSEVPEAEHDPEAEFKAPEDTAVEAETEKGSKETLELEEQLK-AMLPEFPEDGYPNVPEMEPLKEVLANYLIAWKQLEPIISDS-LVPVLTVDISNKTPKELLQRVIEMMEKPFKYGAWELNAEDYEEEAEDYQAEMEVEEEQEEEEEEEEEGEEKSKERRRHLGDTKHFCPVVLKENFVLQPGSTEEAVKYREKIYYFSTPEAKEKFLEHPEDYVSQNEPLKAPPLRICLLGPHGSGKTVCARKLAENFGIFHIQFEEFLQERMLLKAERKFGPEFEDDSE-----------EEQAMKQELEELAAQANVKIEED---NTKKQLPEVQFTEEEEAIKLSLTDNEPLPSEILDPMLSEWWLKEPIRSTGFILDGFPRYPEEAQFLGERGFFPDAAVIIQVDDQDIFDRLLPAQVQKWKTKQLKKSERKKMIKEMKAKIKEDMVAKRRAELISEREKRKKGEGAFRDEEEFSDEDA-------EDE-DDIENILEEEFPKDEEEMS-EEDEEQEGDATERLRSELGEKFETETNNIQSIQDEFERFLIPIIPVNGARKMHIVQYVLNVKLKPLVENRASIFEKCYPVSPHLAHKMLAFTYKHMSSFGYWDPVKLSEGETIKPVETAENPLNPIIHRHYIYFLSTKQTKEKFMMNPIKYIRQPKPKASMPVRIMIVGPPKSGKSTVAKQLANDYGLKCLSMGDALRGMLSNHPEAELSLRINWHLHKGMTVPDDLAIQALDISLLDSVCNTVGVVIDGYPVTPHQVELLEARSIIPMIIFELDVPSKEIFKRLLLEKKSEQGMPYPMHNSTQIIAYRNAKYRKNVNEIRQFYQRQHQNWHVIDGFHSKWWVWNEVIKDIQQMNKYIQTYMEKIKEGKAACIDKLCITPEELISRLGEFKQFCPVSLAESNELIDCSVTSSLEFTAEFRGHYYKMSSQEKLNKFLKNPELYVPPLAPHPLPPDDMLPKRLTLSELKSRFPMSAELQGYCPVTYKDGKQRYEALVPGDNEYAVEYRGRIYICESEEKLQKFLRLPMKYWDQKLPHKLPPPKESIHLTSLPLPGYLEQGTATSLIKAMNAAGNLKPKLPFLSVRRSVLLYIAFHLKAFNPKGSEYSRKKYKKKMEQFVERCELITYLSSKMTRKFKEPQFRPIDFDHKLQTFMSLKNIDPVTG--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3UYQ4-1", "uniprot_id": "KAD9_MOUSE", "id": "G3UYQ4-1", "name": "Adenylate kinase 9", "aln": "MASEEKTEELHPFTDIFNEDETDRNCLLSKPTCFIIFGKPGAGKTTLARNIAQAWKCIRVEALSVLEEHIAAEKETGAMLQSLLVSGHSIPDELVTKLILEKIKSPEVAHFGYILTEMPSLAQDNMTSLKQIELVKNLELQPDIIINIKCSDYDLCQRTCGQRQHSTTGYVYTREQWDPEIIESRRRKKRDFPKEGKSEEEEEEEEQEEEEAFIAEMQMVAEILQHLVQRPEDYLENVEITVKLYKELLLSALEEVMAEHNPQYLIELDGNKSPEELFMTVIERLKYLNVRRAAVITKLQGTEE-EMTDIIDTEELFRTVSSYKLIAPRYRWYRSKWARSCPVSLKDGNIYSGAADYTVSFLGKMYCLSSEETLKLFSLNPRPFLLPPMPLPPCKVFIFGPEHIGKTTLANLIAEHFKAKVIDYAKLVQPRFDSAREKLIKDTITEATNTAIKVVQQRLLNEKQAKQQEERTLKELQVQYSKREYNDFLS----KSSEELPS----LENTGS-KLSSLEIGQEDKSKSETTITGDQVKD-------------------------------VSTEESIEEVTENHPEVFAILEDTLRHAKELNFEQPHDKQAEILEEVIKETE-DNKNRFPGAPKHGGWIVENFPLVRELWLSLIEKA--LLPDLVVYLSDAESNGKHVLNRLYLKNKAEIDGKILERLQEEAQAKKREEEEIRKVKEEELRLEEEKQRLMELATKKSKGRHRLTTLVAHHLALPYPDYPDNEAEEEVEDSEIHEESEAQEIPEYTRGSSLPEASETSETPEGDHEPEAEFKPPGDTAVEAETEKDPKEGLGSEDLLK-VMLPEFPEDGYPNVPEMEPLKEVLNNHILSWKQLEQTIMDN-VVSTLTVDVSNKTPQELLQRVVETMERPFKYSAWELNAEDYEEEAEDYQAETEIDEEQEEEEEEEEEGEEKIKEKRRHMGDTKHFCPVVLKENFVLQPGNPDEAVKYREKIYYFSSTEAKEKFLEHPEDYVSQNEPLKAPPLRICLLGPHGSGKTVCARKLAENFGIFHIQFDEFLQEKMLLKAERKFGPEFEDDSE-----------EEQLVKQELEELAAQANVKIEED---TTKKQLPDVQLTEEEEAIKLSLTDNEPLPSEILDSILSEWWLKEPIRSTGFILDGFPRHPEEAQFLGERGFFPDAAVIIQVDDQDIFDRLLPAQVQKWKTKQHKKLERKKLIKDLKTKIKEDMVAKRRAELILEREKKRREDGTFRDEDEFSDEDA-------DYE-DDIENILEEEFPKDEEEMS-EEDEEQEADATERLRNELGEKFETETNNIQSIQDEFDKVLIPIIMVNGARKMHIVQYVMNMKLKPLVENRESIFEKCYPVSSHLAHKMLSYTYKHMSSFGYWDPVKLSEGETIKPVENAENPLNPVIHRHYIYFLSNKQTKEKFMMNPIKYIRQPKPKATMPVRIMIVGPPKSGKTTVAKKLASDYGLRCLSVGDALRGMLNNHPDSELSLMLNWHLHKGKTVPDELAIQALDISLMESVCNTIGVVIDGYPVTPHQMDLLEARSIIPMVIFELHVPSKEIFKRLLLEKKTEQSMSYPLHNSSQIIAYKNAKYHKNINEIRQFYQKQHQNWHVIDGFHSKWWVWNEVLKDIQQMNKYIQTYMKKIKEGKAACIDKLCITPEELIARLGEFKQFCPVSLAESNELIDCSVTSSLEFAAEFRGHYYKMSSQEKLNKFLKDPELYVPPLAPHPLPPDDLLPKRLTLSELKSRFPKCAELQGYCPVTYQDGKQRYEALVPGNIRYALEYRNCIYICESEEKLQKFMRSPMQYWNQKLPRKLPPLKESIHLTSLPLPGYLEQGTATSLIKAMNAAGNLKPKLPFLSVRRSVLLYIAFHLKAFNPKGSEYSRKKYKKKLEQFVERCELITYLSSKMTRKYKEPQFRAIDFDHKLQTFLSLKNIDPVTG--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TCS8-4", "uniprot_id": "KAD9_HUMAN", "id": "Q5TCS8-4", "name": "Adenylate kinase 9", "aln": "MTSQEKTEE-YPFADIFDEDETERNFLLSKPVCFVVFGKPGVGKTTLARYITQAWKCIRVEALPILEEQIAAETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSLSQDAMTTLQQIELIKNLNLKPDVIINIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENIVKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNLKRAAILTKLQGAEE-EINDTMENDELFRTLASYKLIAPRYRWQRSKWGRTCPVNLKDGNIYSGLPDYSVSFLGKIYCLSSEEALKPFLLNPRPYLLPPMPGPPCKVFILGPQYSGKTTLCNMLAENYKGKVVDYAQLVQPRFDKARETLVENTIAEATAAAIKVVKEKLLRELQARKQAETALREFQRQYEKMEFGVFPMEATHSSIDEEGY----IQGSQRDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKETGETFTFKRHSQDASQDVKLYSDTAPTEDLIEEVTADHPEVVTMIEETIKMSQDINFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKKG--IIPDLVIYLSDTENNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKVKAK-------------EAEETDN-EDEEEIEGDELEVHEEPEASHD---TRGSWLPEEFEASEVP--ETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEA-YIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEEEEEE--EGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSE-----------NEQAAKQELEELAIQANVKVEEE---NTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRR-ENVVRDDEEISEEEL-------EEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGELGEKFEADTHNLQIIQDELERYLIPIISINGARRNHIVQYTLNMKLKPLVENRASIFEKCHPIPAPLAQKMLTFTYKYISSFGYWDPVKLSEGETIKPVENAENPIYPVIHRQYIYFLSSKETKEKFMKNPIKYIRQPKPKPTVPIRIIIVGPPKSGKTTVAKKITSEYGLKHLSIGGALRYVLNNHPETELALMLNWHLHKGMTAPDELAIQALELSLMESVCNTAGVVIDGYPVTKHQMNLLEARSIIPMVIFELSVPSKEIFKRLLLEKENEQRLPYPLHNSAQIVAVNNVKYRKNIGEIRQYYQEQHQNWYVIDGFHSKWWVWNEVIKNVQMVNKYMQTYLERIKAGKAACIDKLCITPQELLSRLGEFEQFCPVSLAESQELFDCSATDSLEFAAEFRGHYYKMSSQEKLNKFLENPELYVPPLAPHPLPSADMIPKRLTLSELKSRFPKCAELQGYCPVTYKDGNQRYEALVPGSINYALEYHNRIYICENKEKLQKFLRSPLKYWEQKLPHKLPPLREPILLTSLPLPGYLEQGIATSLIKAMNAAGCLKPKFPFLSIRRSALLYIALHLKAFNPKGSEYTRKKYKKKMEQFMESCELITYLGAKMTRKYKEPQFRAIDFDHKLKTFLSLRNIDPING--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0YPK2-1", "uniprot_id": "A0A8V0YPK2_CHICK", "id": "A0A8V0YPK2-1", "name": "", "aln": "MASREEKQS-QPFADIFNEDEAEKFFLLSKPTCIMVLGKPGSGKKTLARKIAQIWKCILIEASEVIQMNIHEETEYGLKCQELLFKGQSISEELVTEMILEKIESPEVAHFGYVLSGFPSLSEEYMTVSQQMEKIKNLKLKPDFLINIKCSDYDLCQRISGQRQRPDSGQVYQRNQWDPDLIEKQKKNSDQLE-----DENEEVEAEEMEEEIAQDSLTMSEMIHQLVQRPEDMLENIQERVGLYKDIMLRSLEDLMAEQDSQYLIELDGNQEPDELLASVVIRLQSMGVRNGAPIIRLQSQQE-EMLEGLENDELFRVLSSVKLIAPRYRWRRSRWGQVCPVALKKGDILMGIPDLAVSFLGKMYTLSSPEALKAFMLNPRPYLLPPMPMPPCKVLVFGPPVSGRTTICNLIANKYKGKVLDMAELIQSHVEELREKNIEQ--RDAIEKTITAMENRLEFEKQLE--EPGGLEELSVKEAD-------------------------NSEETEKMRKEINFEEGSSTEETAVIP----------------------------------------EEMLELSADHPEVQAMVEEAVESASESEVTLSPEIYAEVLERAIAELMKKNKDRFPGAPEKGGWVVDNYPLSEDHWSALSERG--LLPDTVVCLKDTENDGGCILHRTYLANKDEINSKILRRLADEALKKEEEEEEERREMQEMLTPEEEEQ---------------------------------SQEDAEKKESEDDDKQLSSET---------------------EQTSQKQSSDSADYTEESETTE--------------IMLPEFEENDLLDLPEMQTIKEKIDLFMNDWQTMESEIKQSSLVQVVALEIAEQTPESLLNQIILVMEEPFKYHGWELSNEDLDEEAEDLAAEAEAIEDNEAEEEENEEDEEKAKERKRHMGDTKHFCPVSLKEDYVLYPGLPEHAAKYQEKIYYFSNLEYRDKFLKNPEEYVAHNEPLQAPPLRVCLLGTRGSGKTACARWLADKFGIFHIQFKEYLQELLLPKTKEKIGLDFDEEPEEA---------DDEIQLQELQDLS-QTTTKTDDE---ESKQ---EVELTEEEEAIKANLMDAQPLPPEILDNIVPVWWKKEPFRSTGFILDGFPRTSDEAQYLSERGLCPDAAVYIHVEESEILDRLLPPRLKKWKERQHKKAEIKKKLKDLKAKIKNEKIARRRAELLAEQKKRKEKVLEDGENYETSEEED-------ETANEDIEAILEEEFFEEEEEEP---EEEQEIDAVERMQNEIVERFDSERESIEGVQEELQNFLIPQMEINGRRKLRIVRYQIYCKLNSLVENRGSIFEKCYPISLPLAHKMLVFSYKFPSSFSQWDPIKLKEGEIIKPAQNYETTLLPVIHRQYVYFFSSKKNRETFMNNPIKYICQPKPKPPVPVKIAIVGPPKSGKTTVAKKFESTYGLRRLSMGDAIRLVLNNQPESELGLQLKCHLHRGLTVPDELAIQALDVALMDHVCSTTGVVIDGYPVTRKQVNLLESARIIPLKIFELEMDAKEVFRRALLDKESTNRPSYPVHDSTQILAIKNSYYREHIDAIRTYYKKERQNWCVIDAFQSKWWMWDKVLREVQVIVKEIQIYLERIKEGKAASIADLCITPEELQYRLGEFGQYCPVSLADKGELVDCSVTSSLQFAAEFRAHYYKMASQEELDKFLNRPEVYVPPLAPHPLPPPDKLPQRLTAAEVKALFPISAEMQGYCPVTYLDGKQRYEALVPGNTEYAAKYQDKLYVFESEEKLLKFMRLPEKYWNLKLPHKLPPVREPILLTALPMAGYLEQGVATSLIKALNEVGCLKPKFPFLSVRRTALLFVACHLKAYNARSPAHRRQAYRRRLARLTEHCELIPYLGRAMPREYTEPQHRPLGFDLKLQTFLSLKDAGPSFV--------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "A0A2R9YJL3-1", "uniprot_id": "A0A2R9YJL3_DANRE", "id": "A0A2R9YJL3-1", "name": "", "aln": "MSSDLIVSN-LPLVDKLIEDEAERAILLSKPACFIIIGKPGVGKSTLAKKIAKTWNCILIDDTDVLNNHINNETDQGKQLFRILAEGKAVPEEMMVNLIVDRLKSPDIKHYGYVLACLPSISEEYMKIQEQIDLIKTLKMSPDFIINIKCADRDLIRRLSEERQHPETGCVFPKEKWDPDKKESLMKQSNMEEEEEEEEEGEEETTEDLEVEEIEEIQLQKDVIAQLVRVTENYPENVTSRIKCYKDNILRPLEDYMAGHNPPYLFELDGNTDPEELFESVMSHLEFMAVRCPAVPVQLMPTEDAELTDQMEPEELFRTLSSCRNVAPGFPWRTSRWAFNCPVALKEGKVIKGKPEFAVGFMDKIYVLSSDDALQKFMANPRCYLLQPKPHVPCRVSVIGPPRSGKSTMCGLLAEKYGALVVDVRELMERNQGLLKQDMLNKVRHDATIAGLEKVRAKMELE----------------------------------------------------------------------------------------------------------------ATAIEVTEDHPDVQAFVEEAIKEAAES--PAPRELYLDALEKHIKEIEAEDAD----AESKRGWILD-IPSSRSHLITIEEIHGALTPEIIFCLKDNDREGRTVLTRMYERNKEEVDQAVMTRLQNQRNLQKTQDHETLKHSEDSKKDS-------------------------------------QYSDTLSKLETVHEESESSDK----------------------------SDDEGKTPSKNE-----------------VVLPTVWENGHPDGPEMDVFKVELKQFVTDWESMEQTITCS----YAVLEINNKTPQGILQEMTDHMEKPFKHKAIMTSSADLEEEEEAIHMLIQAEKQDDVVNEEEEQESEEFN-FKRQLGDTKHFCPVVLKEKGLLQPCLDEYAAKYRDKVYYFSSKEALEKFLQNPELYISNKELLKPPALRVSMLGVRGSGKTTHGKWLAQQLGIFHIQFRERLQELIQRKTQKRVSPADDSEPPEEPPEELQSLLKAQARIQSAESPTDQDNTTSLEETASGSPDAKEEEALTEDEEAIKAYLQNGDPLPSEILEMLLFQWWNQEPYKSTGFILEGFPQNHEEVSFMAEHHLFPDVVAVMSVEVSEVVRRLLPSRLNRWRERRERKQQQIHLVMKLRKEIRERAITKRRAEIMAEQAFRKLSPPTLSPLKEQEEEEEKEEAVDEEQELEEIEAMLLEEFPPEDEEETEDEEQETEESAEERLEVEISERFEKDDDNLTSMTDLLSDNQIPRLVISAGRLPRIVRYQLLKEIKPLMENRDSLFQTCQPISYSLARRLLYCSFKYPSAFGCWDPVKYTEGDLIQPPQDSYHSTFPVILHQFIYFFASKETRNTFILNPIKYLRQPRPNPSLPIKLAIIGPPKSGKTTVAQAFAREYGLTRLSIGDAIRMVLNSQAKTDLACQVQIHLKQGQTVPDELAIQCVEVAVMNLVCTTRGFVLDGFPVTKHQAELLES-CIIPMVVVELQLDTVEVLKRGLRDREKNNRSHQVHHDSLQALNIRNSCFRQEAEALRLHLHNQYHNWTPVDAHKSKWWVQERILDEVRISMRHIHSYLERIHKGQAACINRLCITPQELQSRLGEFGHYCPVSLALHRHLVDCSHNTSLELAAEFKGQFYKMASREFLERFLESPEQFVAPGCPYPLPPASLLPHKLSAGQVKSRFPQQVEMKGFCPVTYLDGKQRYEALLRGNMEYAAEYRNKIYIFESEKKQEQFLRSPETYWDQKLPHKLPPLEEPVLLTSLPILGYLEQSVAVPIIKAMTDVGQLKPKFPFLSVKRSAILYLAFHLKAFNSRNSEYIRQKYKKKLQKFEEGCELISYLSTTMK-TYKSPLNLPTEFLQKLDRFLALEKSTKTDSGLIQLGGI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 538, "similar_positions": 651, "identity": "27.3%" }, { "cls_id": "homologset.oma.815967", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A520-1", "uniprot_id": "D4A520_RAT", "id": "D4A520-1", "name": "Protein phosphatase", "aln": "MFSVLSYG-RLVARAVLGG-----LSQTDPRAGGGGGGG---SGDYGLVTAG-------------CGFGKD-----FRKGLLKKGACYGDDACFVARHRSADVLG-VADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSN-----PVGILTTSYCELLQNKVPLLGSSTACIVVLDRSSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPE-------AEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNS-NYESIQRTARSIAEQAHELAYDPNYMSPFAQFACDN-----------GLNVRGGKPDDITVLLSIVAEYTD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NVE9-1", "uniprot_id": "PPTC7_MOUSE", "id": "Q6NVE9-1", "name": "Protein phosphatase PTC7 homolog", "aln": "MFSVLSYG-RLVARAVLGG-----LSQTDPRAGGGGGGGGGSSGDYGLVTAG-------------CGFGKD-----FRKGLLKKGACYGDDACFVARHRSADVLG-VADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSN-----PVGILTTSYCELLQNKVPLLGSSTACIVVLDRSSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPE-------AEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNS-NYESIQRTARSIAEQAHELAYDPNYMSPFAQFACDN-----------GLNVRGGKPDDITVLLSIVAEYTD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NI37-1", "uniprot_id": "PPTC7_HUMAN", "id": "Q8NI37-1", "name": "Protein phosphatase PTC7 homolog", "aln": "MFSVLSYG-RLVARAVLGG-----LSQTDPRAGGG---GG---GDYGLVTAG-------------CGFGKD-----FRKGLLKKGACYGDDACFVARHRSADVLG-VADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSN-----PIGILTTSYCELLQNKVPLLGSSTACIVVLDRTSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPE-------AEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNS-NYESIQQTARSIAEQAHELAYDPNYMSPFAQFACDN-----------GLNVRGGKPDDITVLLSIVAEYTD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RNM7-1", "uniprot_id": "F1RNM7_PIG", "id": "F1RNM7-1", "name": "Protein phosphatase", "aln": "MFSVLSYG-RLVARAVLGG-----LSQTDPRAGGGSGSGG---GDYGLVTAG-------------CGFGKD-----FRKGLLKKGACYGDDACFVARHRSADVLG-VADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSN-----PIGILTTSYCELLQNKVPLLGSSTACIVVLDRTSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPE-------AEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNS-NYESIQQTARSIAEQAHELAYDPNYMSPFAQFACDN-----------GLNVRGGKPDDITVLLSIVAEYTD", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "E1BEW5-1", "uniprot_id": "E1BEW5_BOVIN", "id": "E1BEW5-1", "name": "Protein phosphatase", "aln": "MFSVLSYG-RLVARAVLGG-----LSQTDPRAGGGGGGGG---GDYGLVTAG-------------CGFGKD-----FRKGLLKKGACYGDDACFVARHRSADVLG-VADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSN-----PIGILTTSYCELLQNKVPLLGSSTACIVVLDRTSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPE-------AEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNS-NYESIQQTARSIAEQAHELAYDPNYMSPFAQFACDN-----------GLNVRGGKPDDITVLLSIVAEYTD", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A8V1A8D0-1", "uniprot_id": "A0A8V1A8D0_CHICK", "id": "A0A8V1A8D0-1", "name": "Protein phosphatase", "aln": "MFSVLSYG-RLVARAVLGG-----LSQTDTR-------------DYSLVTAS-------------CGFGKD-----FRKGILKKGMCYGDDACFVARHRTADVLG-VADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSN-----PVGILTAGYCELLQNKVPLLGSSTACIVVLDRTSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPE-------AEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNS-NYESIQQTARSIAEQAHELAYDPTYMSPFAQFACDN-----------GLNVRGGKPDDITVLLSIVAEYTD", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9W0E2-1", "uniprot_id": "Q9W0E2_DROME", "id": "Q9W0E2-1", "name": "Protein phosphatase", "aln": "MHSSLSWTSRAISRALRSS-----FSTLLETATGGGSGAAAKGATKSGATPGSSGAPRPRFVSVVCGFAKD-----NLRHKYKPGK-YGEDSWFKASTASADVMG-VADGVGGWRSYGIDPGEFSSFLMRTCERLVQCSHFNPQR-----PVNLLAYSYCELMEQKKPILGSSTACVLILNRETSTVHTANIGDSGFVVVREGQVVHKSEEQQHYFNTPFQLSLPPPG-------HGPNVLSDSPESADTMSFPVRDGDVILIATDGVFDNVPEDLMLQVLSEVEGERDPVKLQMTANSLALMARTLSLNSEFLSPFALSARRN-----------NIQARGGKPDDITVVLATVAM---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38797-1", "uniprot_id": "PP2C7_YEAST", "id": "P38797-1", "name": "Protein phosphatase 2C homolog 7, mitochondrial", "aln": "MFANVGFRTLRVSRGPLYGSCSQIISFSKRTFYSSAKSGYQSNNSHGDAYSSGSQSGPFTYKTAVAFQPKDRDDLIYQKLKDSIRSPTGEDNYFVTSNNVHDIFAGVADGVGGWAEHGYDSSAISRELCKKMDEISTALAENSSKETLLTPKKIIGAAYAKIRDEKVVKVGGTTAIVAHFP-SNGKLEVANLGDSWCGVFRDSKLVFQTKFQTVGFNAPYQLSIIPEEMLKEAERRGSKYILNTPRDADEYSFQLKKKDIIILATDGVTDNIATDDIELFLKDNAAR-TNDELQLLSQKFVDNVVSLSKDPNYPSVFAQEISKLT----------GKNYSGGKEDDITVVVVRVD----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "O64730-1", "uniprot_id": "P2C26_ARATH", "id": "O64730-1", "name": "Probable protein phosphatase 2C 26", "aln": "--MAIPVTRMMVPHAIPSLR----LSHPNPSRVDFLCRCAPSEIQPLRPELS---------------LSVG-----IHAIPHPDKVEKGGEDAFFVSSYRGGVMA-VADGVSGWAEQDVDPSLFSKELMANASRLVDDQEVRYDP------------GFLIDKAHTATTSRGSATIILAMLEEVGILKIGNVGDCGLKLLREGQIIFATAPQEHYFDCPYQLSSEGSA--------------QTYLDASFSIVEVQKGDVIVMGSDGLFDNVFDHEIVSIVT------KHTDVAESSRLLAEVASSHSRDTEFESPYALEARAKGFDVPLWKKVLGKKLTGGKLDDVTVIVAKVVSS--", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.:. :* . . * : * . .::. *****.** . . *.. :* * . ..: . .: .. .::: : : :. .*:**. :.* .:::. : * *: *:*** :: *. . :: *:*: .:**: **: : :. .: :. :. . : :. : * :* . : *** **:**:: * ", "identical_positions": 40, "similar_positions": 82, "identity": "11.14%" }, { "cls_id": "homologset.oma.816069", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KBB4-1", "uniprot_id": "A0A0G2KBB4_RAT", "id": "A0A0G2KBB4-1", "name": "", "aln": "MPR-TRNTGDLCPISEDTTHSGRSRRSAQRS-YINRMAEATPANMNDPLLLPLRINPPGLSLAQFILGYMSWLTYLACFLRTQAQQVLLNTCRFKLLFQKLIEKMGLLVLCVFGFWMFSMHLPSKMEVWQDDSISGPLQSLRMYQEKVRHHTGEIQDLRGSMNLLIAKLQQMEAMSDEQKMTQKIMKMIQGDFIEKPDFALKSIGASIDFEHTSPTYNHDKARSYWNWIRLWNYAQPPDVILEPSVTPGNCWAFAGDRGQVTIRLAQKVYLSNVTLQHIPKTISLSGCLDTAPKDFVIYGMEHPPREEVFLGAFQFQPENIIQTFQLQNQPPRGFAAVKVKISSNWGNPRFTCLYRVRVHGCATPPKR-SYL-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DA32-1", "uniprot_id": "SUN5_MOUSE", "id": "Q9DA32-1", "name": "SUN domain-containing protein 5", "aln": "MPR-TRNIGALCTLPEDTTHSGRPRRGVQRS-YISRMAEPAPANMNDPLLLPLRMNTPGLSLVQILLGYMSWLTYLACFLRTQTQQVFLNTCRCKLFCQKVMEKMGLLVLCVFGFWMFSMHLPSKVEVWQDDSINGPLQSLRMYQEKVRHHTGEIQDLRGSMNQLIAKLQKMEAISDEQKMAQKIMKMIQGDYIEKPDFALKSIGASIDFEHTSATYNHDKARSYWNWIRLWNYAQPPDVILEPNVTPGNCWAFASDRGQVTIRLAQKVYLSNITLQHIPKTISLSGSPDTAPKDIVIYGLESLPREEVFLGAFQFQPENVIQMFQLQNLPPRSFAAVKVKISSNWGNPRFTCMYRVRVHGSVTPPKD-SHLEPLS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TC36-1", "uniprot_id": "SUN5_HUMAN", "id": "Q8TC36-1", "name": "SUN domain-containing protein 5", "aln": "MPRSSRSPGDPGALLEDVAHNPRPRRIAQRGRNTSRMAEDTSPNMNDNILLPVRNNDQALGLTQCMLGCVSWFTCFACSLRTQAQQVLFNTCRCKLLCQKLMEKTGILLLCAFGFWMFSIHLPSKMKVWQDDSINGPLQSLRLYQEKVRHHSGEIQDLRGSMNQLIAKLQEMEAMSDEQKMAQKIMKMIHGDYIEKPDFALKSIGASIDFEHTSVTYNHEKAHSYWNWIQLWNYAQPPDVILEPNVTPGNCWAFEGDRGQVTIQLAQKVYLSNLTLQHIPKTISLSGSLDTAPKDFVIYGMEGSPKEEVFLGAFQFQPENIIQMFPLQNQPARAFSAVKVKISSNWGNPGFTCLYRVRVHGSVAPPREQPHQNPYPKRD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** :*. * .: **.:*. *.** .**. .**** :..**** :***:* * .*.*.* :** :**:* :** ****:***::**** **: **::** *:*:**.*******:*****::*******.*******:********:*********** ******:***:******:*******:**:********************* ****:**:******:**************.********* .*******:*********:*************. ******:****:* *:**************:** * *** *.*.*:************* ***:*******..:**: .: ", "identical_positions": 271, "similar_positions": 65, "identity": "71.5%" }, { "cls_id": "homologset.oma.816070", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TAQ9-1", "uniprot_id": "SUN3_HUMAN", "id": "Q8TAQ9-1", "name": "SUN domain-containing protein 3", "aln": "----------------------------------MSGKTK-ARRAAMFFRRCSED----------ASGSASGNALLSEDE------NPDANGVTRSWKIILSTMLTLTFLLVGLLNHQWLKETDVPQKSRQLYAIIAEYGSRLYKYQARLRMPKEQLELLKKESQNLENNFRQILFLIEQIDVLKALLRDMKDGMDNNHNWNTHGDPVEDPDHT----EEVSNLVNYVLKKLREDQVEMADYALKSAGASIIEAGTSESYKNNKAKLYWHGIGFLNHEMPPDIILQPDVYPGKCWAFPGSQGHTLIKLATKIIPTAVTMEHISEKVSPSGNISSAPKEFSVYGITKKCEGEEIFLGQFIYNKTGTTVQTFELQHAVSEYLLCVKLNIFSNWGHPKYTCLYRFRVHGTPGKHI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1MH03-1", "uniprot_id": "F1MH03_BOVIN", "id": "F1MH03-1", "name": "SUN domain-containing protein 3", "aln": "----------------------------------MSGRPN-SRGSSRLFRAPSED----------ASSGSSGSAVLPQQE------NPNASGLTRSWKAVMGMVFILTLLLLGFINHMKLKEKAFPQKSRQIYAVIAEYGSRLYNYQARLRMPKEQLELLKKESQTLENNFREILFLIEQIDVLKALLRDMQDGLHN-YSWNADIDPAEGWNHTEVIDEEMSNLVNYILKKLREDQVQMADYALKSAGASVVEAGTSESYKNNKAKLYWHGIGFLNYEMPPDIILQPDVHPGKCWAFPGSQGHALIKLARKIIPTAVTMEHISEKVSPSGNISSAPKEFSVYGVLKQCEGEEIFLGQFVYNKTGTTVQTFALQHEVPEFLLCVKLKILSNWGHPNYTCLYRFRVHGTPKDDS", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0ABK0LWX8-1", "uniprot_id": "A0ABK0LWX8_RAT", "id": "A0ABK0LWX8-1", "name": "SUN domain-containing protein 3", "aln": "MVWCGEQVRVRKRKVLLSPGSLGAADRLARWEQRLQGQSQRARGSTRLQLTHLQTPYAQELARPLRSHGSTVSTLNTQEEHMRQNIQPERIQLTGSWKIILSTVFASTFLLVGLLNHQWLKETEFPQKPRQLYTVIAEYGSRLHNYQARLRMPKEQQELLKKESQTLENNFREILFLIEQIDLLKALLRDMKDGVHN-HSWPAQREAVQDQATAEVLDEEMSNLVHYVLKKFRGDQIQLADYALKSAGASVIEAGTSESYKNNKAKLYWHGIGFLNYEMPPDMILQPDVHPGKCWAFPGSQGHILIKLARKIIPTAVTMEHISEKVSPSGNISSAPKEFSVYGVTKKCEGEEMFLGQFIYKKMEATIQTFELQNEASESLLCVKLQILSNWGHPKYTCLYRFRVHGIPSDHT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SS91-1", "uniprot_id": "SUN3_MOUSE", "id": "Q5SS91-1", "name": "SUN domain-containing protein 3", "aln": "-------------------------------------------------------------------------------------------MLTRSWKIILSTVFISTFLLVGLLNHQWLKETEFPQKPRQLYTVIAEYGSRLYNYQARLRMPKEQQELLKKESQTLENNFREILFLIEQIDVLKALLKDMKDGVHN-HSLPVHRDAVQDQATTDVLDEEMSNLVHYVLKKFRGDQIQLADYALKSAGASVIEAGTSESYKNNKAKLYWHGIGFLNYEMPPDMILQPDVHPGKCWAFPGSQGHILIKLARKIIPTAVTMEHISEKVSPSGNISSAPKEFSVYGVMKKCEGEEIFLGQFIYNKMEATIQTFELQNEASESLLCVKLQILSNWGHPKYTCLYRFRVHGIPSDYT", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *** ::. :: *:**:*::** ***. .***.**:*::********::*********** ********.******:*********:*****:**:**:.* :. .. :..:. : **:****:*:***:* **:::***********::************************:*****:******:************* ***** *********************************: *:*****:*****:*:* :*:*** **: ..* ******:*:******:*********** * . ", "identical_positions": 226, "similar_positions": 61, "identity": "54.85%" }, { "cls_id": "homologset.oma.816099", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q53GL7-1", "uniprot_id": "PAR10_HUMAN", "id": "Q53GL7-1", "name": "Protein mono-ADP-ribosyltransferase PARP10", "aln": "MVAMAEAEAGVAVEVRGLPPAVPDELLTLYFENRRRSGGGPVLSWQRLGCGGVLTFREPADAERVLAQADHELHGAQLSLRPAPPRAPARLLLQGLPPGTTPQRLEQHVQALLRASGLPVQPCCALASPRPDRALVQLPKPLSEADVRVLEEQAQNLGLEGTLVSLARVPQARAVRVVGDGASVDLLLLELYLENERRSGGGPLEDLQRLPGPLGTVASFQQWQVAERVLQQEHRLQGSELSLVPHYDILEPEELAENTSGGDHPSTQGPRATKHALLRTGGLVTALQGAGTVTMGSGEEPGQSGASLRTGPMVQGRGIMTTGSGQEPGQSGTSLRTGPMGSLGQAEQVSSMPMGSLEHEGLVSLRPVGLQEQEGPMSLGPVGSAGPVETSKGLLGQEGLVEIAMDSPEQEGLVGPMEITMGSLEKAGPVSPGCVKLAGQEG-------------------------------------------------------------------------------LVEMVLLMEPGAMRFLQLYHEDLLAGLGDVALLPLEGPDMTGFRLCGAQASCQAAEEFLRSLLGSISCHVLCLEHPGSARFLLGPEGQHLLQGLEAQFQCVFGTERLATATLDTG-----LEEVDPTEALPVLPGN----AHTLWTPDSTGGDQEDVSLEEVRELLATLEGLD------LDGEDWLPRELEEEGPQE------QPEEEVTPGHEEEEPVAPSTVAPRWLEEEAALQLALHRSLEPQGQVAEQEEAAALRQALTLSLLEQP----PLEAEE--PPDGGTDGKAQLVVHSAFEQDVEELDRALRAALEVHVQEETVG----PWRRTLPAELRARLERCHGVSVALRGDCTILRGFGAHPARAARHLVALLAGPWDQSLAFPLAASGPTLAGQ----------------------------------------------------------------------------TLKGPWNNLERLAENTGEFQEVVRAFYDTLDAARSSIRVVRVERVSHPLLQQQYELYRERLLQRCERRPVEQVLYHGTTAPAVPDICAHGFNRSFCGRNATVYGKGVYFARRASLSVQDRYSPPNADGHKAVFVARVLTGDYGQGRRGLRAPPLRGPGHVLLRYDSAVDCICQPSIFVIFHDTQALPTHLITCEHVPRASPDDPSGLPGRSPDT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1MRP9-1", "uniprot_id": "F1MRP9_BOVIN", "id": "F1MRP9-1", "name": "Poly [ADP-ribose] polymerase", "aln": "-MGEAEAEVGAAVELSGLPTSIPDELLTLYFENRRSSGGGPVASWQRLGRGGILTFEEPADAARVLAWPEHTLQGARLSLRPAPPRASARLLLQGLPPGTTPQLLEQYVQALLCATGHPEQPCHALASPRPDRALVQLPKPLSEAEAGVLEVHSRALGLEGAEVSLAWVPQARAVRVVGGDPPADLLLLELYLENERRSGGGPLEGMHSLPGHLGTVVSFQHWRVAERVLQRDHRLQGSELKLVPHYDVLEPEELAEDAGEGSCPGDLGPGAPRHVLQEAGGPAREQHYAGDVTLGSEEAPGQSGASLSTGPQWDS------------------------SSLAPAGPVSSGPWGSSEEEGLGSRRTVGSPD-------------------------------------------PVEIAMRSSEQVASVSQGPAGSPGQQG-------------------------------------------------------------------------------LVEMVLAMEPGAMRFIQLYHEDLLTGLGDVALFPLEGSDTTGFRLCGALAPCRAAKEFLQSLLGSVSCHMLSLKHPGSARFLLSPEGQHLLRELEAQFQCVFRTEHLAGAVLDMD-----LEEVGPTEALQALPGL----SSTPWPPDDPDRDQENSGLEEVRELLATLEG--------LDGEDWLPLELGEEEPEG------QPEEEVTIPRSGEEPLAPSTREPGWLQEEAELQLALYRSLQPRGQAAEQEE-AELQQALALSLLEPP----PLSGEQELLWGQGPGGWAQLEVHASFERDMDELDRALEAALEVHLREELVG----APGCVLPAELCARLERCHGVSVALHGGHIVLRGFGVQPTHAAHHLAALLAGPRDQSSAFPLAASCSTLPQQ----------------------------------------------------------------------------RPKEPLGRLERLAESSSEFQAVVQAFCDTLDTAHGRIHVVRVERVLHPLLQQQYELHRERLEQCCER-PAEQVLYHGTAMPTVPDICAHGFNRSFCGRNGALYGQGVYFAKRASLSVLDRYSPPDAEGHKAVFVARVLTGDYGQGQRGLRAPPPRPAGHALLRYDSAVDCLHRPSIFVIFHDTQALPTHLITCKHKSRSLPEDAPALLSTSPATWP", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "D3ZZ94-1", "uniprot_id": "D3ZZ94_RAT", "id": "D3ZZ94-1", "name": "Poly [ADP-ribose] polymerase", "aln": "---MAEEESGAALELWGLLPEIPDELLTLYFENHRRSGGGPLLSWQRLGCGGILVFQDPADAKRALAQTEHRLHGVQLTLRPAPPRAPERVLLQHLPPGTSPLSLEQHVQALLCAAGHPVQTCCVLASPRQDCALVQLSMPLSEADVCALVEQARNLPLNGATVSLAWVPQTRAVRVVDSPASVDLLLLELYLENERRSGGGPLEGMRSLPGKLGTVISFRQWQVAERVLKQKHWLQGSELCLVPHYDVLEPEGLAEGISGGDHSATQESGVTDGALTEAGGLAASLT----VAVGSGEAPGQLGTFLRAGPVETPG-------QAMPVDPGSVR-QGIMGSASSGDPVESFTE-RPEQAGPMTTDSVGVQECEG------------------------LEEVAIGSPGQEGTRGLVGTAMES-VETGLESPGYGEMQKHED-------------------------------------------------------------------------------LVEMVLSMEPGAMRFLQLYYEDLLVSLEDVALFPLEGVDVTGFRLCGARAPCQAAQELLQSLLGSVSCHMLNMKHPGSARFLLGVEGQHLLHRLEAQFQCVFGTEHLASATLVID-----PERTDPTEALQVLHA------------HSTGINQESMRLEEVQELLATLEG----------LEDRVPLEMEEEKAGEPEETVLEREEEIPTLEAEEEP-----GAPGQLEEEATLQLAIHRSLESQSQVADQQEANALRQAMALSLLEAE----EPLDED-------TRGRAQLVVHTSFEQDMDELNQALSDALEGHLQEETVS----LQGCMLPSELAARLERCYDVSVTLHGDHAGLRGFGVQPARAARHLSALLVGPQDQNLTFPLEASKNNLSEQ----------------------------------------------------------------------------GLKEPLGRLETLEENSKEFQDVVRAFYDTLDAAHSKICIVRVERVSHPLLQQQYQLHRERLMQRCQQQPVEQVLYHGTSESAVLDICAHGFNRSFCGRNGTLYGQGVYFAKRASLSVLDRYSPPNAEGHKAVFVAQVLTGDYGQGSRGLKAPPLRASG-QVLRYDSAVDCLHQPKIFVIFHDTQALPTHLITCKNIHLGTP---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CIE4-1", "uniprot_id": "PAR10_MOUSE", "id": "Q8CIE4-1", "name": "Protein mono-ADP-ribosyltransferase PARP10", "aln": "---MAEVEAGAALELRGLPPEIPDELITLYFENHRRSGGGLLLSWQRLGCGGVLIFQDPADAKRVLAQAEHRLHGVRLSLRPAPPRAPERVLLQHLPPGTSPLSLEQHVQALLGAAGHPVQTCHALASPRQDCALVQLSTPLSEAEVSALAEQARNLPLNGATVSLAWVPQTRAVRVVDSASPVDLLLLELYLENERRSGGGPLEGLRSLPGQLGTVISFQQWQVAERVLKQKHWLQGIELSLVPHYDVLEPEALAEGVSGRDHSATQESGVIGHAPTGTGGLAGALT----MAVGSGEAPQQLGTLLRAGPVGAPG-------QALPVDSGSIRIQGSMGSTSPVDPVESSTE-LPEQVGPMASDSVGVQEQEG------------------------LGEVATG---QEGLMGLVGTAMES-VETGLESPGYGEMQKQEG-------------------------------------------------------------------------------LVEMVMSVEPGAVRYLQLYYEDLLASLEDVALFPLEGTDVTGFRLCGARAPCQAAQELLQSLLGSISCHTLNMKHPGSARFLLGVEGQHLLHRLEAQFQCVFGTEHLASATLDID-----PERTDPTEALQVLHG------------HITGIDQESLRLEDVRELLATLESP-------HGGEDRVPLEMEKEKPGGPGETVVEQQEEIPTLEAEEEPVALSTGARGQLEEEATLQLAIHRSLESQSQVADQQEANALRRAMALSLLEAE----EALDED-------TGGEAQLVVHTSFEQDVDELNQALSNALEAHLREETVS----LQGRMLPPELGARLERCHDVSATLRGDRVVLRGFGVQPARAARHLAALLVDPWDQNLTFPLEASKPNLSEQ----------------------------------------------------------------------------GLKEPLGRLEALEENSQEFQDVVRAFYSTLDAVHGRIRIVRVERVSHPLLQQQYQLHRERLMQSCQQRPVEQVLYHGTSESAVLDICAHGFNRSFCGRNGTLYGQGVYFAKRASLSVLDRYSPPNAEGYKAVFVAQVLTGDYGQGSRGLKAPPLRVSG-QVLRYDSAVDCLQQPRIFVIFHDTQALPTHLITCKNILPGTP---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PNZ8-1", "uniprot_id": "A0A8M9PNZ8_DANRE", "id": "A0A8M9PNZ8-1", "name": "Poly [ADP-ribose] polymerase", "aln": "---MADSLEERSLEVLDIPDDLDDDFLVLYFENKRRSGGGRVVSLERRGNQALVVFED-AETAVSVSSKSHSLHNTTLTLRRKPPKDPGKLLLRGLNPDTPMDYVELFVENITRLD--LETEFTLYPSPNKDLVLIHLKK-RPSKDFQTLSDDVSKKSLHGAKVSLEQVVATDSILVSN-LSTQTEDVLELYFG-SIRSGGADVVAVSMLSDGR-AKVSFKDVKTVDRVLQKSHNLEDRDLVVEPYFDFLHAVVGQASAASQDGQSTLMDGMNLTEPVSSQSPTVSHPMDSTSLGQANAQTNIIPVIPNLTPATAAEP----LIQKECVSFVSVPDAAKHNLLRLSKLTEDLTKAHPQFDVSLAKDGVQIKGPDQIEVERLKNKVLEFLTG-VVQDHQTYDKLKADFLGREDVKKRLDSSLKDFPSIYSVSDCTVTVTSSSRNTARQTHDLLKSRISEFTVPVANEYKSAIFSEEWSDFLTSLDFCSTTVSEDAGRINVVTLAGMEKDNKGKIVEFLSTPHQKETVLSMQPGMLKFLQLHHQDLLADMGEVILFPLESG--DGLSIQGDANVCQSAAELLSAIIGSVFTRSIVVKHPGISRFLLDDEGTSILAEMTAKFEVYIDMTKVHWEPLEDKDILELAWKMTPCQNFQKSSSANSIQEFTAGVPNGATDAHASARIEEAKKILAVIGSDFNPAPSSSGSTNTDTQDIYSDPSEEIIEVNSDSDDQPQPLQTLDLPSFSAPTNVCNLDEDASLLLAIQLSMEINQRKDNDDIQKALELSKRDSVPREENKQLEMAFEMSMEEAIRLSNTAEIFVYANYNHDLVRVDIALGKKVGLRQCEEKIENKILRKLSSFQKRCIDLIKRKHAVEINIQGTTAILSGFKEYVSVAVPDLKDVLRRTEHMMSDAGIAKSVQWVWYEQGSSKGTPYSPEATVFIENAWKLKQKKIDILFNNQPYSIDLEKMEEHSLASGKSVPIKRKMMSTEDLYTDGADEDYSLLSSMPEVSTVDVNSDEFQDVVKEFYDTLQDNHNKIRIIKVEKLMNKLLHDQYRLKKASIEQSTSEPQFERTLYHGTSETSVKEICIHGFNRSFCGKNATVYGQGVYFAVNASLSVSDTYSPPNADGHKFIFVAKVLTGEFTVGKHEMKAAPLKENSAVPFRYHSVTDQINSPTLFVIFNDTQAYPKYLITCKKIYG------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: ::*: .: : *:::.*****:* **** : * :* * .:: *.: *:: :: .* *:.. *:** **: . ::**: * *.*. :* .*: : .**. * .*::* .. : .* . *.*: *** * : :: * . .. :****: . ****. : : *.. : **:. :..:***::.* *:. :* : *::*.*.. . . . . : . . : . . * . ... . : : * : :: . . * . * *: ::** ::::**:::***..: :* *:***. *: : * *::* *:* :::**: : : ::*** :****. ** :* : *:*: : :: * . * : : . . . : . :*:.:::**.: . : . :: .: . : ::: . : * *:*:* * **: *:: . : ::: *. : *: . * . *:: *:: :::*: .:: ** : : ** : : . ::* : *. ::* * ** : *. .* :* . . : * : : . .:. : .: *** **: * .**: :. * :::**:: : **::**.* : : * .. *:.*****: .:* :** *********:*.::**:***** .***** * ****:*:*:* :***:****:: * : ::*.* : . :**.*..* : * :****:**** *.:****:: ", "identical_positions": 219, "similar_positions": 282, "identity": "18.05%" }, { "cls_id": "homologset.oma.816100", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K3Y6-1", "uniprot_id": "ZCCHV_RAT", "id": "Q8K3Y6-1", "name": "Zinc finger CCCH-type antiviral protein 1", "aln": "MADPGVCCFITKILCAHGGRMTLEELLGEIRLPEAQLYELLETAGPDRFVLLETGGQAGITRSVVATTRARVCRRKYCQRPCDSLHLCKLNLLGRCHYAQSQRNLCKYSHDVLSEQNFQILKNHELSGLNQEELACLLVQSDPFFLPEICKSYKGEGRKQTCGQPQPCERLHICEHFTRGNCSYLNCLRSHNLMDRKVLTIMREHGLSPDVVQNIQDICNNKHARRNPPGTRAAHPHRRGGAHRDRSKSRDRFLHNSLEFLSPVVSPLG-SGPPSPDVTSCKDSL--EDVSVDVTQKFKYLGTHDRAQLSPVSSKAAGVQGPSQMRASQEFSEDGNLDDIFSRNRSDSSSSRASA---AKVAQRNEAVAMKMG------MEVKGKKEAPDIDRVPFLNSYIDGVTMEKASVSGIPGKKFTANDLENLLLLNDTWKNVAKPQDLQTTGRITD----SGQDKAFLQNKYGGNPVWASASTHNAPNGSSQIMDETPNVSKSSTSGFAIKPAIAGGKEAVYSGVQSPRSQVLAVPGEATTPVQSNRLPQSPLSSSSHRAAASGSPGKNSTHTSVSPAIESSRMTSDPDEYLLRYILNPLFRMDNHGPKEICQDHLYKGCQQS-HCDRSHFHLPYRWQMFVYTTWRDFQDMESIEQAYCDPHVELILIENHQINFQKMTCDSYPIRRLSTPSYEEKPLSAVFATKWIWYWKNEFNEYIQYGNESPGHTSSDINSAYLESFFQSCPRGVLPFQAGSQKYELSFQGMIQTNIASKTQRHVVRRPVFVSSNDVEQKRRGPE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3HH79-1", "uniprot_id": "G3HH79_CRIGR", "id": "G3HH79-1", "name": "", "aln": "MADPGVCCFITKILCAHGGRMTLEELLAEIALPEAQLRELLEAAGPDRFVQLEIVGQTGVTRSVVATTRARVCRRKYCERPCDSLHLCKLNLLGRCHYSHSQRNLCKYSHEVLSEQNFQVLKNHELSGLNQEELAVLLVQSDPFFMPEICKSYKGEGRKQICGQPQPCERLHICEHFTRGNCSYLNCLRSHNLMDRKVLAIMKEHGLSSDVVQNIQDICNSKHSRRNPPAMRAPQPHRRG-RARGRSKSRDRFFQNSLEFL-PTVSPAE-SGPPSPDATSCKGSL--EDVSADVTQKFKYLGTQDCAQLSSVSPKAAGLRG-----AGLKFSENGDPGGLFSRSCSDSSSNLAASGFHLDVTQTLEAMAKKTDKLSGYHMDVKNRSKAHDKQHVPFFDSCAGGAKMEG-TASGILGNRATANGLGEILPSN-HRKSAGNLLDLQITSRVADSIADSGQDMAFLGGKYGGNTVWASKSTHSDPNGSSQIMNKTPDVSKSSATGFGVKAAVTGRKEAMSFGGQSLRSQVLAMPEEITAAVPASRLPQTPPPSSSHRVAASEILGKNSTHATVSPVCKPSRRTSDSEYPLFSIASSTSPRMDDHGPKEICQDHLYKGCHQS-NCNKSHFHLPYRWQLFIDNSWVDFQDMEDIERAYCDPQTESVMIGEYQINFQKMTCDYFPIRRLSTPSFDAQSVNSVFSTTWLWYWKDEFNKYVQYGDENKSHLSSNISSSYLESFFQSCPRGVLPFQAGSQNYELSFQGMIQTNIASKTQRRVVRRPVFVAWKDVERRRRGADRQPVMPAVEALTLDSPPLRDTGTFPFPSNRYELVELDSQDVEYATISELFKASMKYFKIVSIKRIWNQDLWETFERKKLMMKN------DNEMLLFHATCRVHVDYICRNNFDWIINDSRETKYGKGNYFAKEAMYSHKNCSYEAKNIVMLVARVLAGNSIEGNMRYSSAPA-------LYDSCVDSRLNPSVFVIFQKEQIYPAYVIEYTELEK-EKACIIS", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "E1BCF8-1", "uniprot_id": "E1BCF8_BOVIN", "id": "E1BCF8-1", "name": "", "aln": "MADPGVCCFITKILCAHGGRMALEELLHEMQLSEEQLCEVLKEAGPDRFVVLEMGGKEGVTRSVVATTRARVCRRKYCNKPCGNLHLCKLNLLGRCHYSQSERNLCKYSHEVLSEDNFRVLTNHGLSGLNQEELAVLLLQSDPFFMPEICKNYKGEGGRQICNQQPPCERLHICEHFTRGNCGYANCFRSHNLMDRRVLAVMREHGLSSSVVQNIQDICNSRHRQKKPSAWKAPPPHRRDLAFRGRSKSRD---RGSEEFLPAASASAQRSCSPSPEPPGHRGSVASDGPVEDLARQFSHLGSQECPPPASNPSAAVVLGGTPQGGGNQRLAENGSAKDLFYGNHSHAPLTFDLK---------------------------------------PAFN-----------------------------------WKGPASWQNDQDTGKKS-----WLPSSPVFSSSPGSPQTP---ETRKTTAVLS--SDHVNAERRSGNQDGQHFPLFADKADGMAVDTTSTRRANYQTPSSRQREKSLPRNPDTGTPRSHLPTAGQMTGDG--AAAFVNDSVPNVASTISS-------------TMNEHSSNEICLDHLYKSCQLK-SCNKVHFHLPYRWQMLLANSWVDLPFMEDIEKAFCDPKNCSVSVRTYNINFQKMICDFNPVRRISTPSSVTQPPSSLLTTKWIWYWRNG-TKWVPYGEKKDNEQISSIDSSYLESLFLSCPRGIVPFQAGSRNYELSFQGMIQTNIASKTQKDVIRRPTFVSYWDVEQVKRRQDPQQGQTSSEPFINIYLPQPDTSVP--GSNGFELLEIPSNTPEYAKVSDHFKASMRNFKIEKIKKVQNAQLLEAFKSKKNEMK-------REEQILFCATERSNVASICKNNFDWLLHGSHDTKYGKGNYFTKDAFSSHKNCPFDSRNIVMFVARVLVGNFIEGHTSYRSPPL-------QYDSCVDTRLNPSVFVIFQKDQIYPEYVIEYTEPERSEKPCLIS", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A286ZZJ3-1", "uniprot_id": "A0A286ZZJ3_PIG", "id": "A0A286ZZJ3-1", "name": "", "aln": "MADPGVCCFITKILCTHGGRMALEELLQKVKLSEAQLCEVLTTAGPDRFVLLETGGKAGVTRSVVATTRVRVCRRKYCNRQCGNLHLCKLNLLGRCHYSQSERNLCKYSHEVLSDENFRVLNSHELSGLNKEELAVLLVQSDPFFMPEICKNYKGEGGRQICNQQPPCERLHVCEHFTRGNCSYSNCFRSHNLMDRKVLAVMREHGLSSSVVQNIQDICNSRHRRNKPSGARAPSSHRRD---RGRSKSRERLCQDSVEFLPSASAAARVSRTPSPDSAG-RHSSPDDGLVEHLATKFKGLGSHDCPQLSSVSSAATSQGGTGPRGGSQSFLENGSPESLLLVNCGGSIFSLASP---------------------------------------PAPN-----------------------------------WKGPTSWQNNKDPSRESS----FSPNQAVTFSPLGSPQTPQATSTRKSPTLFS--SDFVNLEGRSGNQDGQPFQLFHNNVDAVATDVASRKSLSYKSATSRQREKSLPRSPDAGAAHGLLQPAGKVAEDAA-AAAFGNGSAPDARSTASS-------------MMDDHGSNEICLDHLDKGCQLK-NCSKVHFHLPYRWQMLSANTWMDLSLMENVEEAFCDPKVSVLSIGNYKLNFQEMTCDYNPIRRLSTPSSVTRPPGTVFTTKWVWYWKSGPNTWVRYGEKKDN-QISNIDSAYLESFFLSCPRGIVPFQAGSQNFELSFPGMIQTNVASKVQKDVVRRPTFVSHWDVEQMKRGMGPPQVQPQLEPPAPTFLPQWDTHFS--ASNGYKLLEIHNYTPEYVEVSGRFKASMKNFKIDKIKKIQNTKLLNAFERKKHEVK-------VER-ILFCVKRRADVESICANNFD--SDGTHDTKYGKGIYFTKDAISSHKDCPYDSKNVAMFVVRVLVGNFVEGHPYFTSPPL-------GFNSCVDTRLNPSVFVIFEKDQIYPEYLIEYTET---DKPCVIS", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q7Z2W4-1", "uniprot_id": "ZCCHV_HUMAN", "id": "Q7Z2W4-1", "name": "Zinc finger CCCH-type antiviral protein 1", "aln": "MADPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVVLETGGEAGITRSVVATTRARVCRRKYCQRPCDNLHLCKLNLLGRCNYSQSERNLCKYSHEVLSEENFKVLKNHELSGLNKEELAVLLLQSDPFFMPEICKSYKGEGRQQICNQQPPCSRLHICDHFTRGNCRFPNCLRSHNLMDRKVLAIMREHGLNPDVVQNIQDICNSKHMQKNPPGPRAPSSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASL-EDAPVDDLTRKFTYLGSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNST---------------------------------------SAPN-----------------------------------WKSLTSWTNDQGARRKTV----FSPTLPAARSSLGSLQTPEAVTTRKGTGLLS--SDYRIINGKSGTQDIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHREISSPRIQDAGPASRDVQATGRIADDADPRVALVNDSLSDVTSTTSS-------------RVDDHDSEEICLDHLCKGCPLNGSCSKVHFHLPYRWQMLIGKTWTDFEHMETIEKGYCNPGIHLCSVGSYTINFRVMSCDSFPIRRLSTPSSVTKPANSVFTTKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVVPFQAGSRNYELSFQGMIQTNIASKTQKDVIRRPTFVPQWYVQQMKRGPDHQPAKTSSVSLTATFRPQEDFCFL--SSKKYKLSEIHHLHPEYVRVSEHFKASMKNFKIEKIKKIENSELLDKFTWKKSQMK-------EEGKLLFYATSRAYVESICSNNFDSFLHETHENKYGKGIYFAKDAIYSHKNCPYDAKNVVMFVAQVLVGKFTEGNITYTSPPP-------QFDSCVDTRSNPSVFVIFQKDQVYPQYVIEYTED----KACVIS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0ZRG1-1", "uniprot_id": "A0A8V0ZRG1_CHICK", "id": "A0A8V0ZRG1-1", "name": "", "aln": "MGDPVVCSFLTKTLCAEGGRLGLAELQQHVGLSAQQLQETLQAAGPERFLLLTG---AGGAPEVLALTAVRICMRKQCEG-CERLHLCKLHLMGRCSLRHR---VCKYSHDITSAENKKVLKTHELSGLSENELRILLLQNDPFLLPDACQFYNN--RVNTCSQRDDCNKLHICRYFLHGGCKFFPCKKSHNFLDSCALRLLKNGGIDEKMASNIQKVYDHKH----------VELHKRE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KPNGPSYKPRQTSEEDRTNKSSKEQKPSFETP-EVSTVHAPPSEAVLFSQPSHADRSSNKTHQSEREFLTG--------------TRSKVEGKKDDSSVNSSK--------------DNKDKSDEICLFNVWKYCKHNEKCTSVHYHLPYRWQVYNGITWNDLSMMEEIEKAYCDPKNS--SAADKGINFQTMTLSSSLIRRLSTPSSVVNP-TFVLTTKWIWYWKNDHGQWTEYGTQGEQGIVNSPSSDILENLYLADPDTTIQFQAGLYYYQLNFKEMIQINTSSKTKRKVCRRPKFVSYEEVQKIKERGQRDSIPSQACPPHWDQSALPD--------FGYKEVEISTISSEYQEIKKQFEQTMKSCNIIKILRIQNPSLWKVFQWQKEQMKRQSGGKEVKERLLFHGTMGCLLEDICSHNFDWRVCGSNGNLYGKGSYFASDASYSHGYCQSAGKSTVMFMARVLVGDYAQGKEHYVRPPAKLVGGFQFYDSCVDDVANPSIFVIFEKNQIYPEYLIEYKDVQ---KKCIVC", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.** **.*:** **:.***: * * .: *. ** * * ***:**: * * : .*:* * .*:* ** *: * ******:*:*** : :*****:: * :* ::*..* ****.::** **:*.***::*: *: *:. : *.* *.:**:* :* :*.* : * :***::* .* :::: *:. .:..***.: : :* *:* . * ::. . . : . . . : : : . . . :.. ..*** :: * * . * *:*******: :* *: ** :*..:*:* :**: * . :**:**** .. :::*.*:***:. : ** : .. .* **.:: : * : **** ::*.* *** * :**.:: * *** **. *:: :. ", "identical_positions": 153, "similar_positions": 136, "identity": "15.06%" }, { "cls_id": "homologset.oma.816102", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q460N5-6", "uniprot_id": "PAR14_HUMAN", "id": "Q460N5-6", "name": "Protein mono-ADP-ribosyltransferase PARP14", "aln": "MAVPGSFPLLVEGSWGPDPPKNLNTKLQMYFQSPKRSGGGECEVRQDPRSPSRFLVFFYPEDVRQKVLERKNHELVWQGKGTFKLTVQLPATPD--EIDHVFEEELLTKESKTKEDVKEPDVSEELDTKLPLDGGLDKMEDIPEECENISSLVAFENLKANVTDIMLILLVENISGLSNDDFQVEIIRDFDVAVVTFQKHIDTIRFVDDCTKHHSIKQLQLSPRLLEVTNTIRVENLPPGADDYSLKLFFENPYNGGGRVANVEYFPEESSALIEFFDRKVLDTIMATKLDFNKMPLSVFPYYASLGTALYGKEKPLIKLPAPFEESLDLPLWKFLQKKNHLIEEINDEMRRCHCELTWSQLSGKVTIRPAATLVNEGRPRIKTWQADTSTTLSSIRSKYKVNPIKVDPTMWDTIKNDVK--DDRILIEFDTLKEMVILAGKSEDVQSIEVQVRELIESTTQKIKREEQSLKEKMIISPGRYFLLCHSSLLDHLLTECPEIEICYDRVTQHLCLKGPSADVYKAKCEIQEKVYTMAQKNIQVSPEIFQFLQQVNWKEFSKCLFIAQKILALYELEGTTVLLTSCSSEALLEAEKQMLSALNYKRIEVENKEVLHGKKWKGLTHNLLKKQNSSPNTVIINELTSETTAEVIITGCVKEVNETYKLLFNFVEQNMKIERLVEVKPSLVIDYLKTEKKLFWPKIKKVNVQVSFNPENKQKGILLTGSKTEVLKAVDIVKQVWDSVCVKSVHTDKPGAKQFFQDKARFYQSEIKRLFGCYIELQENEV--------------MKEGGSPAGQKCFSRTVLAPGVVLIVQQGDLARLPVDVVVNASNEDLKHYGGLAAALSKAAGPELQADCDQIVKRE-GRLLPGNATISKAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEKYKYRSIAIPAISSGVFGFPLGRCVETIVSAIKENFQFKKDGHCLKEIYLVDVSEKTVEAFAEAVKTVFKATLPDTAAPPGLPPAAAGPGKTSWEKG-SLVSPGGLQMLLVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEELDTVGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEWR-NGSTSSLKIMEDIIRECMEITESLSLKSIAFPAIGTGNLGFPKNIFAELIISEVFKFSSKNQLKTLQEVHFLLHPSDHENIQAFSDEFARRANGNLVSDKIPKAKDTQGFYGTVSSPDSGVYEMKIGSIIFQVASGDITKEEADVIVNSTSNSFNLKAGVSKAILECAGQNVERECSQQAQQRKNDYIITGGGFLRCKNIIHVIGGNDVKSSVSSVLQECEKKNYSSICLPAIGTGNAKQHPDKVAEAIIDAIEDFVQKGSAQSVKKVKVVIFLPQVLDVFYANMKKREGTQLS-----SQQSVMSKLASFLGFSKQSPQKKNHLVLEKKTESATFRVCGENVTCVEYAISWLQDLIEKEQCPYTSEDECIKDFDEKEYQELNELQKKLNINISLDHKRPLIKVLGISRDVMQARDEIEAMIKRVRLAKEQESRADCISEFIEWQYNDNNTSHCFNKMTNLKLEDARREKKKTVDVKINHRHYTVNLNTYTATDTKGHSLSVQRLTKSKVDIPAHWSDMKQQNFCVVELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQAKKKTMDAKNGQTMNEKQLFHGTDAGSVPHVNRNGFNRSYAGKNAVAYGKGTYFAVNANYSANDTYSRPDANGRKHVYYVRVLTGIYTHGNHSLIVPPSKNPQNPTDLYDTVTDNVHHPSLFVAFYDYQAYPEYLITFRK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1SQ36-1", "uniprot_id": "F1SQ36_PIG", "id": "F1SQ36-1", "name": "Poly [ADP-ribose] polymerase", "aln": "MSEPGSFPLLVEGSWGPDPPKNLSTKLQLYFQSPKKSGGGECEVLQEPGSPSRFLVLFYPNDVRKQVLEREKHELVWPGVGRFTLSVQLPTAPN--EGR---EGKIPTNGSKTKERAKESDVSEDLDEHLSLSKRSEKMEDSPKECENSSSLVAFENLKANVNDTMFIMLVENVSGLTKDDFQVELVRDFNVAVVTFQKHIDARKFVDDCAKHHSVKGLQLSARLLEVTKTVLVENLPPGVDHDDLKRLFENPLNGGGRVASIKCFPEESSALIEYFDREVLDTIVTKKLDFNNMPLSVFPYYTSLGTALYGQEKPLIKLPAPFREVLDLSLWKFLQKESHLIEEINDEARRCHCELTWCQPSGEVIIRPAATLVDQGRLKIKSWQEDASAVFSAIRSKYTVTPLKVDPVVWDTIKDNVG--NDRILIEFDELTRILTLSGKSEDVQNIEPQIKNLIESTIQKIKKEEQSLKQKLTISPARYSLLLHSGIQKHLL--CPEVEMFYDEASQHMCFKGLRADVYKAKCEVQEKVYTMAQKNIQFPPEIFQFLQQVDCAEFSKSLFIAQNILAVYELEGTTVLITGSSSQVLLEAEKQMVSALHYRCIDVEDREVLNSKKWKGLTRNLQKKHNSSSKTVVIHEVTSETTTQVIIAGCVNEVKEIYDLLFAFVEKHTKIEKLIEVKPSLVIDFLRTEKS-FLQKIKKMNVQVVFNPEDKQKGILLTGPKTEVLEAKNIVMQAWNSVCVKSLQIDKPGARQFFQDKSRYYKSEVKRLFGCVIELQKDE---------------EKEGGSRGEQRCFFRTNLAPGVSLIVQQGDLSRFPVEVVVNVTSEDLKFSEGLNDALLKAAGLEYQEEFYQIMKRERGKVSPGCAVISKAGKP---RVIHAEVPPWKRNEAQKSTCQLKIAVKESLQLAVKHKYQSIAFP---SRALGFPSPQYVESIVLAAKERFQNNRDGCTLKEIYIVDGDERTMKSVAESAKTILRDTLPDTVSQLSLPTVVQSDLRKDHENEPSLLSPEGLRILLVKGDVQNAATDVVVNSIPLDLELNRGPLSKALLEKAGPKLQEELKIVGQGVAVEMGTVLQTSGCNLPCQCVLHVVAPDWG-NGNASSHKIMENIIRDCLEITESLSLKSIAFPAIGTGNLGFPKNIFAELITSQVFKFSSKNQPKSLQEVCFLLYPSDHGTIQAFSDEFARRANGNLISDKIPKAGDTQGF------PNLGLHEMKIGPIIFQVASGNIAAEKADVIVNSTSKSFTLKAGVSKAILKCAGESVEMECSQQAQQGHHEYIVTKGGLLKCKNIIHVIGGNDVRRSVSCVLQECEKRNYSSVCLPAIGTGNARQDPDNVATAIIDAIEDFVQKGSVKSMKKVKVVILLPEILDVFYANLKKRKESQPP-----PQQSMMSKIASFLGFSSKSPPKQNLLVLEKKTESAVFQVCGENVKCVDHALSWIQDLIKKEQWPYCNEDEYIRYFDVKEYQELNELQKKLNISIFLERERPLIEVFGITTDVIQARNAIEDMIKRVRSSKEQEYLADRTYDYVEWQYQDSNTFQSFDKITNMQLEDAKKQKKKTIDVKINHQSYTVDLNTCIATDAKGKTLLVQRYAKSEVGIPPNWSDMKQQNVCVVELQPDHPEYKMVASKFNETCSNFTIEKIERIQNPDLWRHYQTKKSNMDAKNSQIINEKLLFHGTDVDSVPFVNGNGFNRSYAGKNATSFGKGTYFAVNSNYSASDTYSKPDVNGKKYMYYVRVLTGTYTLGNKSLIVPPLKDPKNPTDLYDTVTDNIQCPNLFVVFYDYQAYPEYLITFKK", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "F1LZ05-1", "uniprot_id": "F1LZ05_RAT", "id": "F1LZ05-1", "name": "Poly [ADP-ribose] polymerase", "aln": "MAASGPFPLLVEGSWGPDPPKNLINKLQMYFQSRKKSGGGECEVVPEPGNPARFLVLFSPEDVRQNVLEKENHELVWQGKGTFKMTVQLPADPGQASVSKK---AIPEEESKTKEDAVKP---GDLDTTPSPSSRSEEMEDVPKECENISSMVAFEQLPEKVSEMVLTFLVENISGLPSDDFKVELIRDFAVAVVTFQKPIDTKKFIIDCISHRSNQQLQLVPRLLETTNVVRVENLPPGVDDYQLQLFFENPFNGGGRVARVECFPEESSALVEFCDSKVLDTIMAKKHSFNKMPLSVFPYYPSLGTALYGEEKPLVKLPASFQESLDLPLWKFFQKNDHLMEEINDEMRHCHCELTWSEINGKLTVRPAATLVS-HRPSIKTWQRDASAALSGIRSKYDVMVFEVCSPVWDIIKHEL--GDDRVLIEFE--KESLNVAGKSEDVQGISQQIRELIERTTEKLRREEQSLEEKVAISSGKHFLLYHSGFLKDLSKEYPEMEISYDATAQYLCIKGLRADVYKVKCEIQEKVFSMAQKNVPVSSEVFRFLQQVDGQRLSNALFKAQNILATYELKDNALFLIGSSPKDLAEAEAKMLSALSHKHIEVEDKEVLRSNVWKKKIHPLQKRHGSYAAIMVKNELTSGVPAEVVIAGCVKEVNEIHRQLFEFLENHMKVERVVKIDPPLIIDYLKTDKR-LLSKTKKANVSVSFKTKDDPNSILLLGSKSKVLECLDTVKEIRDSVCVRKFQTDKAGARHFFQDKEFYYKMEIRRLYGCIVELKE---------------GEEGEEDSLKEQKCYLQRDIGPGVTLIVHEGDLSLFPVDVVVNAANESLKHIDGLAGTLSKAAGPSLQAECDLIVKKG-GMVPPGNAVISKAGKLPCRYVIHAVGPRWKGDKVLECVNLLKKAVKQSLTLAEEYKCQSIAIPAISSGIFDFPLDLCVASIASAIKDNVQQKQNTHSVKKIYLVDVSAKVAKAFAEAVKTTYRDILS----PASVKALVP-PGKMPQKQGKLLVSPEGLNIRLIEEGVQNAEAHAIVNSVSSDLILNKGPLSQAFLESAGPELQEELTKAGQGVSVSVGTVLQTSGCNLNSRSIFHVVTPPWKSNNSEWSLKIMKNIIRDCLRTTEDLSLQSIAFPAIGTGNLGFPKPEFAKLIISEVLKFSSRNQLKTLQEVQFLLHPKDHENIQAFLDEFDKRSNGD-PSSKNPKAEDTQGIYGSLSSPTLGVHEMNIGPILFQVATGDIIKEVADVIVNSTSCTFNLKSGVSKAILEGAGQNVEQECSRLAQQGKE-YIVTGGGLLKCKSIIHVDGGNDVKRSVSCILEECEQRSFSSICLPAIGTGSAQQDPKVVAKAVLDAIEEFVQKKSVQAVKRVKVVIFQPHILQFFYDNMKEREGSPAP-----VKPSVMSKIASFLGFPTQASPPKNTLVLEKKIELTVFQICGPGVDSVEGTISWLKSLITKEQFSFTNEDECVRDFDTEEYRKLNEMQKRLNIIIELNQKKPLIKVSGISRDVVEARDEIDNMVKSIRLAKEKENQADYVSTFVEWQYIANNTTRCFDKIANMQLEDAWKAKKKHTVVKIQNQDFTVDLSTNTATAPQGLSFTVQRLLKAEAEIPANWSDMKQNKLLVVSLQTSDAEYTMVSRAFHQTCPNFVIEKIERIQNPALWRRYQAYKKIMDEKNGNVINEKQLFHGTEFGSLAQLNSNGFNRSYAGKNATAYGKGTYFAVNASYSAHDTYSKPDANGKKYMYYVRVLTGNYTQGNASLIVPPSRDPQNATDLFDTVADNVINPSIFVVFYDNQAYPEYLITFRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2EMV9-1", "uniprot_id": "PAR14_MOUSE", "id": "Q2EMV9-1", "name": "Protein mono-ADP-ribosyltransferase PARP14", "aln": "MAASGSFPLLVEGSWGPDPPKNLINKLQVYFQSRKKSGGGECEVVPEPGNPARFRVLFSPEDVRQNVLERGNHELVWQEKGTFKLTVLMPTDPEEASASKKSRKESPEEESKTKEDAVKQ---GDLDITHSPSSGSEKTEDVPKECENISSMVAFENLPEKVSEMVLTILVENISGLPSDDFKVEVNRDFAVAVVTFQKPIDIKKFIVDCISHRSNQQLQLAPRLLETTNVVRVENLPPGVDEYQLQLFFENPFNGGGRVARVECFPEESSALVEFCDSKVLDTVMAKTHSYNKMPLSVFPYYPSLGTALYGEEKPLIKLPASFQESLDLPLWKFFQKNNHLIEEINNEMRCCHCELTWSEINGKLTIRPAATLVN-HRLSIKTWQRDASAVLSGIKSKYGVELFEVCSPVWDIIKHELESGDDRVLVEFE--KESLNIAGKSEDVQGMSQKIRELIESTTEKLRREEQSLKEKVAISPGKHYLLHHSGFLKDLSKGFPEMEISYDATAQFLYLKGFRADVYKVKCDIQEKVFSMAQKDVQVSSEVFEFLQQVDSQRLSKSLFEAQNILAIYELKGTALFLVGSSFKDLAEAETKMLSALSHKQIEVEDKEVLISNGWKKKVHPLQKRHSSCATIIVQNELTSETPAKVIVTGCVKEVNEIHRQLFEYLENNMKVERALKIKPSLIVDYLRTDKR-LLSKIKKAHVYVHFKPKDNPNSILLTGCKSKVLECMNLVKEIQDSVCVQRFQTDKAGVRHFFKDKESYYKTEIGRQFGCVIELEEDREEKGEEEDGEEEEGEEEGESSINEQKCHLQRDIAPGVKLFVLEEDLSRFPVDVVVNAANENLKHISGLAQALSKAAGPELQTECDQIVKEG-GVVLPGNAVISKAGKLPCHHVIHAVGPRWKGDKVLECVSLLKKVVRQSLSLAEEHRCRSIAMPAVSAGIFDFPLELCVANIVSAIKEHFQHKRDTHTLKKIYLVGLPAKVARAFAEAVKTTYKDSLSHTAFPSSLKALVP-LGKTPQKQGSLLVSPEGLRIRLVEEGVQNATTHAIVNSISPDLKLNKGPLSQAFLEKAGPKLQEELTRSGQGVSVDVGTILQTSGCNLNSRHVFHVVPPPWKSNNSAWSLKIMKNIIRDCLKTTENLSLQSIAFPAIGTGNLRFPKPEFAKLIISEVLKFSSRNQLKTLQEVQFLLHPKDHENIQAFSDEFDKRNNGD-PSDKNPKAEDTQGIYGSLSSPTLGMHEMNIGPILFQVATGNIIKEVADVIVNSTTLTFDLKSGVSKAILEGAGQNVEQECSLLAKQSNHGYIVTGGGLLQCKNIIHVVGGNDVKKSVSCVLEECEQRNYSSICLPAIGTGNAQQDPNVVAKAIIDAIEEFVQKKSVQAVKRVKVVIFQPHILQFFYDNMKEREGSPAPPKQSPAKQSVMSKIASFLGFPKQASPKKNTLVLEKKIEHTVFQVCGSGVDSVNKTISWLKELITKEQLSYTNDDECVSDFDMEEYEKLNEIQKELNITIEMNQKKTSIQVSGISRDVIKARDEIEGMIKSIRLAKEKESQADYISTYVEWQYIDKNITQCFDKMTNMKLEVAWKAKKKDTVVQIHNQDFTVDLSTNTATAPQGQTFTVQRLVKAEAEIPANWSDMKQDKLLLVNLQTSDPEYNMVASAFRQTCSNFFIEKIERIQNPALWRRYQAYKKSMDEKNGNVRNEKHLFHGTEASSLPQLNSNGFNRSYAGKNATAYGKGTYFAVKASYSACDTYSRPDTNGRKYMYYVRVLTGNYTNGNASLIVPPSRDPQNAADLYDTVTDNDKNPSIFVVFYDNQTYPEYLITFRQ", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .*.***************** .***:**** *:******** :* .*:** *:* *:***::***: :***** * *.::* :*: * . : ***** . : :** . . :: ** *:**** **:****:* :*.: :: :****:***..***:**: *** ******** ** :*: ** .*:* : *** .****.*:.: *******.*. .*: :**** ******* :: ********:*: * :****:::.. .:*:*********.********:****:****.*.* ***.****:**:.**:****:* * *******.: .*:: :*******. * **:** *:*:.:*.*:*** * ::* . :** **.:: :**:*:**: .. : ::*******.:. ::::*** * :*:::*****::*: **..:: ** **.: ..* **:*: ** .:*.: :** *****.**::****::****:: ...*:*.*****: .:*:.** **:*** ***:..:::: ..* : * *** :*:*** :: *:**::*** .: ** : * *::.* . :: :*:** ..::*:::***:**:* : ** ::*:: *:*: :::.*.*::*:*:*:* : * ** :* * *:.::. :.*** * *::**:. : * : :****: .: **.*.::**:** :*: *: * :** :**:: .* *:*. : :.*** *:* : **: :**:****.:.*.**. ** :* **** . * : *:*. * : ** *.****** **** * *. :. ... *: .*: ** ** ::: :***:* : :.** * .*. * *:..* ::: :*:**:*. :. .:.**:.** : *. .: . . : :: *:** **.: *:: .**** :..:***:. ** *.:****:::**.***:***** ****:*.:**:*:**. ** .: ::***.* * *.. * ***::***:*:. **.***:************ *** **:** *:*:****:** *:**** ***:*.** .**** *** :* **: *.* *** ****: * *::**:**.*:****:*:* * ********: :* **:*******: **:.** *** *:* :. **:* **:*:**.**** *****: ***.:*:***::.:**:********.*:*.*. ** *::****:**** *.:::*:*****: *.:*:.** *:*:*: : . : *:***:******..::. :* ****** * :.*::** .* .*: ::**::.** *** .: .:** : ** :**.:***:**.*** * :::::. *:* **: **::**: *: *:* :* :**:* ** ::**** .* :.*:*::*::** * : *** *:*::: :**:*.* ** .:* :: *** *::. **.:******::. :*.* ....**. *: *.:**.:* ********** **. **: *. ** **.: *** *****: .*:. :* ************.::********::.*** ****:**.**:*::******** ** ** ****** ::*:*.:**:***:** *.:**.*** *:********::", "identical_positions": 875, "similar_positions": 537, "identity": "47.89%" }, { "cls_id": "homologset.oma.816103", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q7Z3E1-1", "uniprot_id": "PARPT_HUMAN", "id": "Q7Z3E1-1", "name": "Protein mono-ADP-ribosyltransferase TIPARP", "aln": "MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKK-DQKRLGTGTLRSLR-PILNTLLESGSL---DGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYH---------TVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHN--------SF-FRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A4X1SJL9-1", "uniprot_id": "A0A4X1SJL9_PIG", "id": "A0A4X1SJL9-1", "name": "", "aln": "MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKK-DQKRLGTGTLRSLR-PILNTLLESGSL---DGVFRSRNQSTDESGLHEPMVKKPLEINPSCPPAENNMSVLIPDGTNVGGQITEAHPPTDAPEQVVPIQDHSFPPEAISGTVADSTAGHFQTDLLHPVSSDVPTSPDCIDKVMDYVPGVFQDNSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVSNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNINSIYH---------TVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHN--------SF-FRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "E1BJD9-1", "uniprot_id": "E1BJD9_BOVIN", "id": "E1BJD9-1", "name": "", "aln": "MEVETTEPEPDCVVQPPSP-DEFSCPVRLSEKITPLKTCFKKK-DQKRLGTGTLRSLR-PILNTLLESGSL---DGVFRSRNQSAEESSLHEPMVKKPLEINTSCPPTENSMPVLIPSGTNVGAQMPEAHPPTDAPEQVVPIQDHSFPPETISGTVADSTAGHFQTDLLHPVSSDVPASPDCIDKVMDYVPGVFQDNSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTILPYHWQIKRTTTQKWQSVSNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETAEFDQLRRLSTPPSSNVNSIYH---------TVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHN--------SF-FRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q8C1B2-1", "uniprot_id": "PARPT_MOUSE", "id": "Q8C1B2-1", "name": "Protein mono-ADP-ribosyltransferase TIPARP", "aln": "MEVETTEPEPDCVVQPPSPSDDFSCQMRISEKISPLKTCFKKKQEQKRLGTGTLRSLR-PILNTLLESGSL---DGVFRARDQNRDESSLHEHIVKKPLEINPSCPPAENSMPVLIPDGTNVEGQLPEAHPSTDAPEQGVPIQDHSFPPETISGTVADSTTGHFQTDLLHPVSGDVPTSPDCVDKVMDYVPGAFQDNSFTIQYILDTSDKLSTELFQDKSEEASLELVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVSNDSQEHLERFYCNPENDRMRMKYGGQDFWADLNAMTVFETTEFDQLRRLSTPPCSNSNSIYH---------TFWKFFCRDHFGWREYPESVVRLIEEANSRGLKEVRFMMWNNHYILHN--------SF-FRREIKRRPLFRSCFILIPYLQTLGGVPTQASLPLEATSS-QIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMSGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3H222-1", "uniprot_id": "G3H222_CRIGR", "id": "G3H222-1", "name": "", "aln": "MEMETTEPEPDCVVQPPSPPDDFSCQMRISEKISPLKTCFKKKQDQKRLGTGTLRSLR-PILNTLLESGSL---DGVFRARDQNADESSLHERMVKKPLELNPSCSPAENSMSVLIPDETNVEGQLPEAHPSTDAPEQVVPIQDHSFPPETISGTVTDSTTGHFQTDLLHPVSGDVPTSPDCIDKVMDYVPGTFQDNSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTILPYHWQIKRTTTQKWQSVSNDSQEHLERFYCNPENDRMRMKYGGQDFWADLNAMTVFETTEFDQLRRLCTPPCSNTNAIYN---------TYWKFFCRDHFGWREYPESVVRLIEEANSRGLKEVRFMMWNNHYILHN--------SF-FRREIKRRPLFRSCFILIPYLQTLGGVPTQASLPLEATSS-QIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVAI", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "A0A0R4IVH6-1", "uniprot_id": "A0A0R4IVH6_DANRE", "id": "A0A0R4IVH6-1", "name": "", "aln": "MQEAVDTAEP-ALALPMGTGEFTEQQMGLADKIPLVKPCFKKKHAQRKLDTKCLRALEDPILSTLLSSDALVSGDGVFVPRNPPRPQRNICTAAVEKQSRISQVCLKEEDES----TDADVAASELAVEQKVTDIQRVSIDANERRFPPQ--------------ERDEAAPPS-DVSGS---------KLNDIYTAETLQGANCLAIKE---GEIFQDKSEEASLDLVFELLTQLQYHTHQGDAVSICVDFLQGVCVYGSDCAQHHTVLPYHWQIRRVDTQIWQSISDDSQEQLERLYCNPDNEHVRLKFLGRVFTLDFSAMRVCD-LEFDLVRRLSTPSSSTSTTTPTNTSPTPNCLTVWKYYCRDNFGWREYSEPVVRLIEEASGRGLKEVRFITLQNQYILNIREGFQQNAVFGFRRQIKKRPLFRSSIMLTPYLQTLGGLSSAFLSSLETSGN-QPLSPTSSTPSKMYPETWLPMNNCQDFMRVPVSRDDRSYRTVYSLFHKTVSETKFRILKILRVQNPFLWEKYKRKKEYMSRRMTDMDRMLNERHLFHGTSQDVVEGICKHNFDPRVCGKHATMFGQGSYFARKAVYSHNFSKRSPNGVHYMFLAKVLTGKFTVGNPSMRRPPPLNPRDASSDLFDSCVDNWMDPQIFVIFNDDQSYPYFIVQYEEVGSTVAI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . .** .:. * .. : . : :::**. :*.***** *::*.* **:*. ***.***.*.:* **** .*: : .: ::* .:. * *:. .. . ::. : *: . : ::: **.: : * * * **. * : . : ::: * .: *:**********:*****:.******** :.:.**:*****.*:** ** :***:*******:*. ** ***: :****:***:****:*:::*:*: *: * *:.** * : *** :***.**..*. .: * **::***:******.*.*:******..********: :*:***: * ***:**:******.::* ********:.: .**::.. * :.* . *.:::*****: *: .***::**** :*:*** :*.******.* *:***:****** *************.*:* . **::**************:**************************:** *******:*.:***:*********::*:*. .******:** ..:***:******:::****************::*****..**:*", "identical_positions": 340, "similar_positions": 172, "identity": "50.0%" }, { "cls_id": "homologset.oma.816104", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BZ20-1", "uniprot_id": "PAR12_MOUSE", "id": "Q8BZ20-1", "name": "Protein mono-ADP-ribosyltransferase PARP12", "aln": "MAQAAVAVAEVTQLLCAAGGALELAELRRRLRTSLGTDALERLLRDCGRFVVASRAVVAVGAGREAAAAASERLVLAVSSLRLCRAHQGPKPGCTGLCAQLHLCKFLIYGNCKFLKTGKNCRNGHNLKTDHNLSVLRTHGVDHLTYTELCQLLLQNDPSLLPDICLHYNKGDGPFGSCSFQKQCIKLHICQYFLQGECKFGTSCKRSHEFTNSESLEQLERLGLSSDLVSRLLSTYRNAYDIKNKGSALSKVSPSPAGPQGSSERKDSSGPVSPGTPSQEESEQICLYHIRKSCSFQEKCHRVHFHLPYRWQFLDGGKWKDLDNMELIEEAYSNPSKDRIVYTESAAGFHFDNLDFNSMKFGNTLARRLSTASSVTKPPHFILTTDWIWYWMDEFGSWQEYGRQGSGHPVTTISSSDVERAYLAFCAPGADAQAATLKFQAGKHNYELHFKAFLQKNLVYGTIRKVCRRPKYVSPQDVQMKQSCNTKLHGPKSIPDYWDPAALPDLGFKKITLSSSSEEYQKVWNIFNRTLPFYFVQKIERIQNMGLWEVYQWQKCQMQKQNGGKEVDERQLFHGTSANFVDAICQQNFDWRVCGLHGTSYGKGSYFARDAAYSHHYSKSDTHSHMMFLARVLVGDFVRGSTSFVRPPAKEGQSNAFYDSCVNSMSDPTIFVVFEKHQVYPEYLIQYSTSSKPPASPSIFVALGNLFTSRQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A3V3-1", "uniprot_id": "D4A3V3_RAT", "id": "D4A3V3-1", "name": "Protein mono-ADP-ribosyltransferase PARP12", "aln": "MAQAAVAVAEVTQLLCAAGGALELAELRRRLRTSLGADALERLLRDRGRFVVASREGTGPAT---AAAAASERVVVAVSSLRLCRAHQGPKQGCTGLCAQLHLCKFLIYGNCKFLRTGKNCRNGHNLKTDHNLSVLRTHGIDHLTYTELCQLLLQNDPSLLPDICLHYNKGDGHFGSCSFQKQCIKLHICQYFLQGECKFGTSCKRSHEFTNSENLEKLEKLGLSSDLVSRLLSTYRNAYDIKNKGSALSKVSSSPAGPQGTSERKDSS--VSPGTLSQEESEQICLYHIRKSCSFQDKCHRVHFHLPYRWQFLDGGEWKDLDNMELIENAYCNPSKDRIVYTESAAGFHFDNLDFNSMKLGHTLARRLSTASSVTKPPHFILTTEWAWYWMDEFGSWQEYGRQGTGHPVTTISSSDVEKAYLSFCVPGADAQAAILKFQAGKHNYELDFKAFLQKNLVYGTVRKVCRRPKYVSPQDVQMKQSCNTKLHGTKSIPDYWDPAALPDLGFKRITLSSSSEEYQKVWNLFNRTLPFYFVQKIERIQNLGLWEVYQWQKGQMQKQNGGKEVDERQLFHGTSTNFVDAICQQNFDWRVCGLHGTSYGKGSYFARDAAYSHHYSKSDTHSHTMFLARVLVGDFVRGSTSFVRPPAKEGQSNAFYDSCVNSMSDPTIFVVFEKHQVYPEYLIQYSTSSKPPAGPSIFVALGNLFTSRQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H0J9-1", "uniprot_id": "PAR12_HUMAN", "id": "Q9H0J9-1", "name": "Protein mono-ADP-ribosyltransferase PARP12", "aln": "MAQAG-VVGEVTQVLCAAGGALELPELRRRLRMGLSADALERLLRQRGRFVVAVRAG--------GAAAAPERVVLAASPLRLCRAHQGSKPGCVGLCAQLHLCRFMVYGACKFLRAGKNCRNSHSLTTEHNLSVLRTHGVDHLSYNELCQLLFQNDPWLLPEICQHYNKGDGPHGSCAFQKQCIKLHICQYFLQGECKFGTSCKRSHDFSNSENLEKLEKLGMSSDLVSRLPTIYRNAHDIKNKSSAPSRVPP-LFVPQGTSERKDSSGSVSPNTLSQEEGDQICLYHIRKSCSFQDKCHRVHFHLPYRWQFLDRGKWEDLDNMELIEEAYCNPKIERILCSESASTFHSHCLNFNAMTYGATQARRLSTASSVTKPPHFILTTDWIWYWSDEFGSWQEYGRQGTVHPVTTVSSSDVEKAYLAYCTPGSDGQAATLKFQAGKHNYELDFKAFVQKNLVYGTTKKVCRRPKYVSPQDVTTMQTCNTKFPGPKSIPDYWDSSALPDPGFQKITLSSSSEEYQKVWNLFNRTLPFYFVQKIERVQNLALWEVYQWQKGQMQKQNGGKAVDERQLFHGTSAIFVDAICQQNFDWRVCGVHGTSYGKGSYFARDAAYSHHYSKSDTQTHTMFLARVLVGEFVRGNASFVRPPAKEGWSNAFYDSCVNSVSDPSIFVIFEKHQVYPEYVIQYTTSSKPSVTPSILLALGSLFSSRQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1B7S1-1", "uniprot_id": "E1B7S1_BOVIN", "id": "E1B7S1-1", "name": "", "aln": "MAPAA-LLREVTQVLCAAGGALELEELRRRVRPNVDCDVLDRLLRERGRFLVARRAAG-------AGAAAVERVVLAVSPLRLCSAHLGPKPGCAGLCAQLHLCKSLFYGKCKFLRDGKDCRNGHNLMSNHNVSVLKTHGLDHLNYGELCMLLFQNDPLLLPEICLHYNKGDGPYGSCSFKKHCIKLHVCQYFSQGECKFGTGCKRSHDFSNSENLEKLEKLGMRPELVSKLPSIYRNAHDIKNKSSASIRVPPPPSQSQGTSKRRDTG-SVSLNTATQEESDQICLFHIWKSCSFQDKCSRVHFHLPYRWQVLDGGKWKDLHKMELIEEAYSNPARDRVRCTETSSSFLIGFLNFETMKFGATQARRLSTASSVTKPPHFILTTNWVWYWTDEFGSWQEYGRQGMDHPVTSVTSSDLEKAYLAYCASGSNPQAATLRFQAGKHSYELDFKAFIQKNVIYGTVRKVCRRPKYVSPQDVKMKQTCSINSQGLKNIPDHWDRSALPDTGFKRITVPSSSEEFQKVWSLFTSTMPLYSIQKIERVQNPALWEIYQWQKEQMQKRNGRKMVDERQLFHGTSTGLVDAICQQNFDWRVSGLHGTSYGKGSYFARDAAYSHHYSKTDSNTHTMFLARVLVGEFVRGSTAYVRPPIKEAQGNILYDSCVNSMSEPSIFVIFEKHQAYPEYVIQYTASTKPPAATPTFFSLASFFSGRQ", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1SRP3-1", "uniprot_id": "F1SRP3_PIG", "id": "F1SRP3-1", "name": "", "aln": "MAPAA-LLREVTQTLCAAGGSLGLEELRRRLRPGVGGDALDRLLRECGHCVVVRRAAG-------AGAAAVEPSVLAASPLRLCTAHLGPKPSCHGLCAQLHLCKFVLYGQCKFLRDGKECRSSHTLRSDHNMSVLKTQGVDHLDFSELTVLLLQNDPQLLPEICLHYNKGDGPYGSCSFKKQCIKLHVCQYFSQGKCKFGTGCKRSHDFSNPENLEKLEKLGMRSDLVSRLPSIYRNAHDIKNKSSPLVRVPPPPSRSQGSSERRDTG-SVCPNTAPQEESDQICLYHIWKSCSFQEKCSRVHFHLPYRWQVLDGGKWKDLPKMELIEEAYSNPRRDGITCTESAGSFPIGSLKFDSMTFGGTRARRLSTASSVTKPPHFILTTEWLWYWTDELGSWQEYGRQDMEHPVTSVNSSDLEKAYLAYCTPGSDAKAAILRFQAGKHTYELDFRAFIQKNLAYGTMRKVRRRPKYVSPQDVKMKQTCSVNFQGPKSIPEHWDHSAVPDTGFKRIALHSSSEEFQKVWNLFTCTMPNHCIQKIERVQNVALWEVYQWQKGQMQKRNGGKAVDERQLFHGTSTSLVDAICQQNFDWRVNGLHGTSYGKGSYFARDAAYSHHYSKSNTKSHTMFLARVLVGEFVRGNTSFVRPPAKEGQGTVLYDSCVNSVSDPSIFVIFEKHQAYPEYVIQYTALTKPMPAASNLLSLASLFSGRQ", "tax_id": 9823, "tax_name": "Pig" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *. : **** ******:* * *****:* .:. *.*:****: *: :*. * ..*** * *:*.*.**** ** *.* .* *********: :.** ****: **:**..*.* ::**:***:*:*:*** : ** **:**** ***:** ******* .***:*:*:*****:**** **:*****.*****:*:*.*.**:**:**: .:***:* : ****:*****.*. :*.. .**:*:*:*:. *. .* .***.:****:** ******:** ***********.** *:*:** :*****:**.** : : :*::. * *.*::*. * * ********************:* *** **:*********. ****::.***:*:***::*..*:: :** *:******.***.*:**:***: *** :** *********** *:*. : * *.**::** :*:** **::*:: *****:****.:*. *:* : :*****:** .***:***** ****:** * ***********: :************* *:***********************:::::* *********:****.:::**** **. .. :*******:*:*:***:*****.****:***:: :** .. :.:*..:*:.**", "identical_positions": 432, "similar_positions": 171, "identity": "60.76%" }, { "cls_id": "homologset.oma.816106", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JTL9-1", "uniprot_id": "A0A0G2JTL9_RAT", "id": "A0A0G2JTL9-1", "name": "Poly [ADP-ribose] polymerase", "aln": "------------------------------------------------------------------MFHKTEEFFPKKTESDVDDMDTSDTQWGWFYLAECGKWHMFQPDTNIQCSVSSEDIEKSFKTNPCGSISFTTSKFSYKIDFA-----------------------EMKQMNLVTGKQRLIKRAPFSISAFSYICENEAIPMPTHWENVNPDVPYQLVSLQNQTHEYNEVASLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGVHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A9J7GH89-1", "uniprot_id": "A0A9J7GH89_CRIGR", "id": "A0A9J7GH89-1", "name": "Poly [ADP-ribose] polymerase", "aln": "---------------------------------------------------------MNWPFHRAQMFHKTEEFFPKKTESDVDDMDTSDTQWGWFYLAECGKWHMFQPDTNIQCSVSSEDIEKSFKTNPCGSISFTTSKFSYKIDFA-----------------------EMKQMNLVTGKQRLIKRAPFSISAFSYICENEAIPMPTHWENVNTEVPYQLVSLQNQTHEYNEVASLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGVHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTFQIHGVSVQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q8CFF0-1", "uniprot_id": "PAR11_MOUSE", "id": "Q8CFF0-1", "name": "Protein mono-ADP-ribosyltransferase PARP11", "aln": "------------------------------------------------------------------MFHKTEEFFPKKTDSDVDDMDTSDTQWGWFYLAECGKWHMFQPDTNIQCSVSSEDIEKSFKTNPCGSISFTTSKFSYKIDFA-----------------------EMKQMNLVTGKQRLIKRAPFSISAFSYICENEAIPMPTHWENVNPDVPYQLVSLQNQTHEYNEVASLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGVHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NR21-4", "uniprot_id": "PAR11_HUMAN", "id": "Q9NR21-4", "name": "Protein mono-ADP-ribosyltransferase PARP11", "aln": "----------------------------------------------------------MWEAN-PEMFHKAEELFSKTTNNEVDDMDTSDTQWGWFYLAECGKWHMFQPDTNSQCSVSSEDIEKSFKTNPCGSISFTTSKFSYKIDFA-----------------------EMKQMNLTTGKQRLIKRAPFSISAFSYICENEAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6RS94-1", "uniprot_id": "F6RS94_BOVIN", "id": "F6RS94-1", "name": "Poly [ADP-ribose] polymerase", "aln": "MCRKYHCLPVNQKIKQSMASWLIEPISLTFIDCLLSGGQLVHTPFVAYKCIITSIHYFRGYSILKEMFHKAEEFLSKTTDSEVDEMDTSDTQWGWFYLAECGKWHMFQPDTNIQCSVSSEDIEKSFKANPCGSISFTTSKFSYKIDFAGVQFTEKARNVQIFETELCKFYHEMKQMNLTTGKQRLIKRAPFSISAFSYICENEAIPMPPHWENVNTELPYQLIPLHNQTHEYNEVASLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGALFGKGTYFARDAAYSSRFCKDDVKHGNTFQIHGVSLPQRHLFRTHKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPRVFVVFDANQIYPEYLIDFH", "tax_id": 9913, "tax_name": "Bovine" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****:**::.*.*:.:**:*************************** **************:******************** *******.*****************************.******.::****:.*:**********.**********************************************************************:***:*********************:************: *******:********************************************::******************", "identical_positions": 303, "similar_positions": 26, "identity": "72.14%" }, { "cls_id": "homologset.oma.816328", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UBB9-1", "uniprot_id": "TFP11_HUMAN", "id": "Q9UBB9-1", "name": "Tuftelin-interacting protein 11", "aln": "MSLSHLYRDGEGRIDDDDD-ERENFEITDWDLQNEFNPNRQRHWQTKEEATYGVWAERDSDD-----------ERPSFGGKRARDYSAPVNFISAG-------LKKGAAEEAELEDSD--------DEEKPVK------QDDFPKDFGPRKLKTGGNFKPSQKGFAGG--------------------------TKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIEAKQRKGKGAVGAYGSERTTQS---MQDFPVVDSEEEAEEEFQKELSQWRKDPSG-----SKKKPKYSYKTVEELKAKGRISKKLTAP--QKELSQVKVIDMTGREQKVYYSYSQISHKHNVPDDGLPLQSQQLPQSGKEAKAPGFALPELEHNLQLLIDLTEQEIIQNDRQLQYERDMVVNLFHELEKMTEVLDHEERVISNLSKVLEMVEECERRMQPDCSNPLTLDECARIFETLQDKYYEEYRMSDRVDLAVAIVYPLMKEYFKEWDPLKDCTYG-----------TEIISKWKSLLENDQLLSHGGQDLSADAFHRLIWEVWMPFVRNI-VTQWQPRNCDPMVDFLDSWVHIIPVWILDNILDQLIFPKLQKEVENWNPLTDTVPIHSWIHPWLPLMQARLEP-LYSPIRSKLSSALQKWHPSDSSAKLILQPWKDVFTPGSWEAFMVKNIVPKLGMCLGELVINPHQQH-MDAFYWVIDWE------------------------------------GMISVSSLVGLLEKHFFPKWLQVLCSWLSN-SPNYEEITKWYLGWKSMFSDQVLAHPSVKDKFNEALDIMNRAVS---------SNVGAYMQPGARENIAYLTHTERRKDFQYEAMQERREAENMAQRGIGVAASS--VPMNFKDLIETKAEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGE--KTWVPTSLQSLIDMAK--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q06AK6-1", "uniprot_id": "TFP11_PIG", "id": "Q06AK6-1", "name": "Tuftelin-interacting protein 11", "aln": "MSLSHLYRDGEGHMDDDED-ERENFEITDWDLQNEFNPNRQRHWQTKEEATYGVWAERDSDE-----------ERPSFGGKRARDYSAPVNFISAG-------LKKGAAEEAELEDSD--------DEEKPVK------QDEFPKDFGPKKLKTGGNFKPSQKGFAGG--------------------------TKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIEAKQRKGKGAVGAYGSERTTQS---LQDFPVVDSEEEAEEEFQKELSQWRKDPSG-----SKKKPKYSYKTVEELKAKGRISKKLSAP--QKEISQVKVIDMTGREQKVYYSYSQISHKHNVPDDGLPLQS-QLPQPGKEAKAPGFALPELEHNLQLLIELTEQEIIQNDRQLQYERDMVVNLSHELEKMAEVLEHEERVISNLSKVLEMVEECERRLQPGCSNPLTLDECARIFETLQDKYYEEYRMSDRVDLAVAIVYPLMKDYFKEWDPLKDCTYG-----------TEIISKWKSLLENDQLLSHGGQDLSADAFHRLIWEVWMPFVRNI-VTQWQPRNCDPMVDFLDSWVHIIPVWILDNILDQLVFPKLQKEVENWNPLTDTVPIHSWIHPWLPLMQARLEP-LYSPIRSKLASALQKWHPSDSSAKLILQPWKDVFTPGSWEAFMVKNIVPKLGMCLGELVINPHQQH-MDAFYWVIDWE------------------------------------GMISVSSLVGLLEKHFFPKWLQVLCSWLSN-SPNYEEITKWYLGWKSMFSDQVLAHPSVKDKFNEALDIMNRAVS---------SNVGAYMQPGARENIAYLTHTERRKDFQYEAMQERREAENMAQRGIGVAASS--VPMNFKDLIETKAEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGE--KTWVPTSLQSLIDMAK--------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "F1MR60-1", "uniprot_id": "F1MR60_BOVIN", "id": "F1MR60-1", "name": "Tuftelin-interacting protein 11", "aln": "MSLSHLYRDGEGHMDDDED-ERENFEITDWDLQNEFNPNRQRHWQTKEEATYGVWAERDSDE-----------ERPSFGGKRARDYSAPVNFISAG-------LKKGAAEEAELEDSD--------DEEKPVK------QDEFPKDFGPKKLKTGGNFKPSQKGFAGG--------------------------TKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIEAKQRKGKGAVGAYGSERTTQS---LQDFPVVDSEEEAEEEFQKELSQWRKDPSG-----SKKKPKYSYKTVEELKAKGRISKKLTAP--QKELSQVKVIDMTGREQKVYYSYSQISHKHSIPDDGLPPQAQPPPPPGKEARAPGFALPELEHNLQLLIELTEQEIIRNDRQLQYERDVVVNLTHELEKAAGALQQEQRAIASLSEVLALVEECERRLQPGCSDPLTLDECARVFQTLRDKYYEEYRMSDRVDLAVAIVYPLMKDYFKEWDPLKDCTYG-----------TETISQWKSLLENDQLLSHGGQDLSADAFHRLIWEVWMPFVRSI-VAQWQPRNCDPMVDFLDSWAPLIPVWVLDNILEQLIFPKLQKEVESWNPLTDTVPIHSWVHPWLPLMQARLEP-LYSPIRSKLASALQKWHPSDSSAKLILQPWKDVFTPGSWEAFMVKNIVPKLGMCLGELVINPHQQH-MDAFYWVIDWE------------------------------------GMVSVSSLVGLLEKHFFPKWLQVLCSWLSN-SPNYEEITKWYLGWKSMFSDQVLAHPSVKDKFNEALDIMNRAVS---------SSVGAYMQPGAREHIAYLTHTERRKDFQYEAMQERREAENMAQRGIGVAASA--VPMNFKDLIETKAEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGE--KTWVPTSLQSLIDMAK--------", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q5U2Y6-1", "uniprot_id": "TFP11_RAT", "id": "Q5U2Y6-1", "name": "Tuftelin-interacting protein 11", "aln": "MSLSHLYRDGEGHLDDDDD-ERENFEITDWDLQNEFNPNRQRHWQTKEEATYGVWAERDSDE-----------ERPSFGGKRARDYSAPVNFISAG-------LKKGAAEEADSEDSD--------AEEKPVK------QEDFPKDLGPKKLKTGGNFKPSQKGFAGG--------------------------TKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIEAKQRKGKGAVGAYGSERTTQS---LQDFPVADSEEEAEEEFQKELSQWRKDPSG-----SKKKPKYSYKTVEELKAKGRVSKKLTAP--QKELSQVKVIDMTGREQKVYYSYSQISHKHSVPDEGVPLLAQLPPTAGKEAKVPGFALPELEHNLQLLIERTEQEIIQSDRQLQYERDMVVSLSHELEKTAEVLAHEERVISNLSKVLALVEECEHRMQPHGADPLTLDECARIFETLQDKYYEEYRLADRADLAVAIVYPLVKDYFKDWHPLEDSNYG-----------TQIISKWKSLLENDQLLSHSSQDLSSDAFHRLMWEVWMPFVRNV-VAQWQPRNCEPMVDFLDSWAHIIPVWILDNILDQLIFPKLQKEVDNWNPLTDTVPIHSWIHPWLPLMQARLEP-LYSPVRSKLSSALQKWHPSDASAKLILQPWKEVLTPGSWEAFMLRNIVPKLGMCLGELVINPHQQH-MDAFYWVMDWE------------------------------------GMISVSSLVGLLEKHFFPKWLQVLCSWLSN-SPNYEEITKWYLGWKSMFSDQVLAHPSVKDKFNEALDIMNRAVS---------SNVGAYMQPGARENIAYLTHTERRKDFQYEAMQERREAENMAQRGIGVAASS--VPMNFKDLIETKAEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGE--KTWVPTSLQSLIDMAK--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERA6-1", "uniprot_id": "TFP11_MOUSE", "id": "Q9ERA6-1", "name": "Tuftelin-interacting protein 11", "aln": "MSLSHLYRDGEGHLDDDDDDERENFEITDWDLQNEFNPNRQRHWQTKEEATYGVWAERDSDE-----------ERPSFGGKRARDYSAPVNFISAG-------LKKGAAEEADSEDSD--------AEEKPVK------QEDFPKDLGPKKLKTGGNFKPSQKGFSGG--------------------------TKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIEAKQRKGKGAVGAYGSERTTQS---LQDFPVADSEEEAEEEFQKELSQWRKDPSG-----SKKKPKYSYKTVEELKAKGRVSKKLTAP--QKELSQVKVIDMTGREQKVYYSYSQISHKHSVPDEGVPLLAQLPPTAGKEARMPGFALPELEHNLQLLIERTEQEIIQSDRQLQYERDMVVSLSHELEKTAEVLAHEERVISNLSKVLALVEECERRMQPHGADPLTLDECARIFETLQDKYYEEYRLADRADLAVAIVYPLVKDYFKDWHPLEDGSYG-----------TQIISKWKSLLENDQLLSHSSQDLSSDAFHRLMWEVWMPFVRNV-VAQWQPRNCEPMVDFLDSWAHIIPVWILDNILDQLIFPKLQKEVDNWNPLTDTVPIHSWIHPWLPLMQARLEP-LYSPVRSKLSSALQKWHPSDASAKLILQPWKEVLTPGSWEAFMLRNIVPKLGMCLGELVINPHQQH-MDAFYWVMDWE------------------------------------GMISVSSLVGLLEKHFFPKWLQVLCSWLSN-SPNYEEITKWYLGWKSMFSDQVLAHPSVKDKFNEALDIMNRAVS---------SNVGAYMQPGARENIAYLTHTERRKDFQYEAMQERREAENMAQRGIGVAASS--VPMNFKDLIETKAEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGE--KTWVPTSLQSLIDMAK--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5ZII9-1", "uniprot_id": "TFP11_CHICK", "id": "Q5ZII9-1", "name": "Tuftelin-interacting protein 11", "aln": "MSMSHLYG-----TDGEDGVEMENFEVSDWDLQNEFNPHRHRHRQTKEEATYGVWAERDSDE-----------ERPSFGGKRSRDYSAPVNFISAG-------LKKSAAEDVSDEDSD--------EDEKPVK------QEEIPKEFVPKKLKTGGNFKPSQKGFVGG--------------------------TKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIEAKQRKGKGAVGAYGSERTSQS---LQDFPVVDSEEEAEEEFQKELSQWRKDPNG-----GKKKPKYSYKTVEELKAKGRINKQLSTP--QKELSQVKVIDMTGREQKVYYSYSQISHKHNIPDD------NPQQLLGKDSKPQGFALPELEHNLQLLIDITEQEIIQSDRQLQYERDMVVNLTHEIQKMSEILSHEETAISNLSKVLDMVEECERRMQPSCENPLTLDECAKIFETLQDKYYEEYRMSDRVDLAVAIVYPLMKDYFKNWDPLKDCTYG-----------TEIIAKWKSLLENDQLLSHGGQDLSTDAFHRLMWEIWMPYVRNI-VAQWQPRNCGSMVDFLDSWVHIIPVWILDNILDQLIFPKLQKEVENWNPLTDTVPIHSWIHPWLPLMQARLEP-LYSPIRNKLANALQKWHPSDSSAKLILQPWKDVFTPGSWEAFMVKNIVPKLGMCLNELIINPHQQH-MDAFYWVIDWE------------------------------------GMISVSSLVGLLEKHFFPKWLQVLCSWLSN-SPNYEEITKWYLGWKSMFSDQVLAHPSIKDKFNEALDIMNRAVS---------SSVGGYMQPGARENIAYLTHTERRKDFQYEAMQERREAENMAQRGIGMAASS--VPMNFKDLIQTKAEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGE--KTWVPTSLQSLIDMAK--------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9Y103-1", "uniprot_id": "TFP11_DROME", "id": "Q9Y103-1", "name": "Septin-interacting protein 1", "aln": "----------------MSDNDYERFEITDYDLDNEFNINRPRGRQSRHQQIYGIWADDSEEESGGEGG----TKRRGRAARKPKDYTMPVNFVAGG-------IQQAGKKKKKALQAD--------DEKGSQKEGAEADQGEESDDSAASGRPAFGQNDPGSSNSSSEEERPTL------SRKQPSTTFQHRSHIASERNVGAWEQHTRGIGAKLLLQMGYEPGKGLGKDLQGISHPVQAHVRKGRGAIGAYGPETAASIGGKTNKSIKVDEDVREAKEFKDQLNKWRKGSAGGAEPMERQGKRYYYKSVEEVIAKGHTSGHLLSEKLSKKLGNVRVIDMTGPEKRVLSGYHALGQAKITPEETLYDTEATEKGS---APACVFAMPELTHNLQLLVSQCEQQIIAIDNQERECSSQQAALESEHRKLEEIVQLERNHIRTLEESLERVERLID------NPDLSLPQAERLFRELLVDYAAEFHEFGLADLAAGVIAPLLKRELVQWQPLENPTEP-----------LPLIKKWRGMLQQGDAAEQQPR-NVFDPYSSLIWAGVMPSFRSS-AAAWQPKEHPPMASLLDAWAPLLPSWVLDSVLEQLVLPRLVAGVQEWDPLTDTVPIDSWVLPWHAILGSKLEEAVYPQIRSKLGIALRAWSPHDRSARAMLTPWQKAFPEEEMQEFLQRYIVPKLQATLGELIINPMHQD-LELWQQVWEWH------------------------------------ELIDPMYMAQLLDRHFFPRWMQVLVVWLNQ-SPDYAEISRWYTGWKSMLSEPLLREPSVKEHLRRALEIMHRASD---------TLLQPTVTP-----------------------TPPPPVPPAPVIMMDLIHPP--AQLEFKELVSQQCADLGIIFAPLPGRREMGKQIYRVGKLFCYIDRHVCMVSDGSFSNWKPVSLNHLLERSQTGIL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9SHG6-1", "uniprot_id": "STIP1_ARATH", "id": "Q9SHG6-1", "name": "Septin and tuftelin-interacting protein 1 homolog 1", "aln": "----MDEYQDMERFSMDNDYEGGRWEGDEFVYQ----KRKEKRKQTKNDATYGIFAESDSDSDDSGGGGSRRKRRKDRDSGRKADLTKPVNFVSTGTVMPNQEIDKDSREHNDEKDRDKIEDNDMIDEDVEVRGGLGIGSSGLGLGFNANGFDDEDNLLPGALGKKIADRAKMRGKAKVEKRGQEGGGAKGGKKNTLGSDIGQFEKSTKGIGMKLLEKMGYK-GGGLGKNQQGIVAPIEAQLRPKNMGMGYNDFKEAKLP----DLKKVEEKKIIGVSVSENEQSHGDRGGKNLWK--KKKVRKAVYVTAEELLEKKQEAGFGGGQ---------TIIDMRGPQVRVVTNLENLDAEEKAKEADVP-------------------MPELQHNLRLIVDLVEHEIQKIDRDLRNERESALSLQQEKEMLINEEEKQKRHLENMEYIADEISRIELEN---TSGNLTLDSLAIRFEDLQTSYPDDYKLCSLSTIACSLALPLFIRMFQGWDPLSDAVHG-----------LKAISSWRKLLEVEEDHN---IWVVSTPYSQLVSEVVLPAVRIAGINTWEPRDPEPMLRFLETWETLLPSSVLQTILDTVVLPKLSTAVEYWDPRRELVAIHVWVHPWLPILGQKLEF-LYQIIQMKLSNVLDAWHPSDSSAYTILSPWKTVFDTTSWEQLMRRYIVPKLQLALQEFQVNPANQN-LERFDWVMKWA------------------------------------SAVPIHLMADMMERFFFPKWLDVLYHWLRA-KPRFEEIQGWYYGWKELFPQELTANERIRIQLKRGLDMLMEAVE---------GVEVSQPRAKAN-------------------ERTQSVPAQAQAQAKAQMDST--EVLSLKEVLEVFAQEQELLFKPKPNRMHNGLQIYGFGNVSVIIDSVNQKLLAQKDGGWFLVTPDDLLRMHNNTTVSAKR", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "A1XDC0-1", "uniprot_id": "TFP11_DICDI", "id": "A1XDC0-1", "name": "Septin and tuftelin-interacting protein 1 homolog", "aln": "----------------------MNIEGDDEEFYN-FNDIKKKRKFTKEDAIYGVFNDGWGDYEDEEES----KMTEEEYYKMKKRYSTPVGFVASG-------IYEPNEHKLKNKDGENIDNDD--DDGEEKKKKKKEKKEKKQKKKEKKEKKEKKNKKKNKYGGGGGN-----------------------NYDDSDNDKSIEDKPVGGIGAALLSKMGYKGTGGLGRDGGGMVEPIKVQVRPKNAGLASVTELNVNSSD-DSDDSDQSEGDTDSDNENKRSLGWKKKEPKLKYDFDEHLESTTTTTFKKKTTTTTATTTTSSTP--------QIVIDMRGPEARLYTGMEEIKHHKHHHHHQHNKEYQNITSILDDQSKP---LSELKHNVDLLLKLKQIDIQNQDNKIKHENDKINNLTRGVEKLKLTIENDKEQIKKVTEILETITTVKKQLD---QSQLDLKQLYKVFKKLKSNYPKEYQNFKLYNLQKELLEPLLKEKLNQWELESNSDNNDNSSLEISKKLSKEMVKWRQLFQESVSVLG---EYQINVYFLIMRDLFLPKFKNYLRSQWDVKKPSNAATLISTWSDTLPDVIQEALLEQSILPKLKVAIEKWDPRTDPIPLDHWLLPWIPLLGSELES-FYPLIRQKIISALQDWHPSDKSAIKILTPWKNIFQSNSMDSLLNRAIIPKLSKSIKDLEINPSNQKSPIEIQWLLRWSNLNNNDNNNNNNNNNNNDNNNNNNSITTTDNINLDSGLITLSTIICILEKDFFTRWLKILLEWLKSPDANLEEISNWYSGWKKQFPKEIISNDKIKSIFNISLNLMKKVLSNETIQKDDEILISQKINSLLNTNINNNNNNNNNINNSYQQQNQQQPIKPISSPSLNSSNNNNIDNISTKQMVEQLAIKNGLLFIPSEKKTNSGQQIYIFDKIPIIIERDLIMYNNNNNNRWEPANIQYLLDKSLNK------", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : : : ::.: **:: : : : **.*:: * : : .. . : : : : . : . . : . :: . *** ** :*** ***:: *: *::.: * . .:. . : : . . : . . : : :: . :*** * : :: . : . . :.** **: *::. : :* *.. : . * . :. : .: : * * . *. * .* ::: : : **. : *. .: : .*: ::: : :: :* .: *: :. ::.:* :* : : :*: ::*:* :: *:* : :.:. *: ** .:: .** .* :: *: .* * * * ** :* **: : . : :: : *:*** : :: :** :*. : * : : :::: **.:*:.:* ** .. ** ** ***. :.. : . :: :. .*::: .. . . :. *:::. . . ::* * : . * *:* ...: *: * .. : *: ", "identical_positions": 98, "similar_positions": 213, "identity": "10.02%" }, { "cls_id": "homologset.oma.816351", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q709C8-1", "uniprot_id": "VP13C_HUMAN", "id": "Q709C8-1", "name": "Intermembrane lipid transfer protein VPS13C", "aln": "MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALS--ELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGAS-IKYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDV-TDPKRPLSFGVTLGELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQR-----SREQILDQLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAES---ELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKYKPY-LPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEK----------TLDVFNIILARQQAQVEVIRSGQK--LRKKSADTGEKRGGWFSGLWGKKESKKK-DEESLIPETIDDLMTPEEKDKLFTAIGYSESTHN---LTLPKQYVAHIMTLKLVSTSVTIRENK-----------NIPEILKIQIIGLGTQVSQRPG---------------AQALKVEAKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSN--KGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHE-KSDLLILDFGTFQLNSKDQG----------LQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQH---------------PSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSAQS--PERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLEN---IIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKEPLEIS-ISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVD------LQSIHKKAVSILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVG--CIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQN------------DIEILKPVNMLLSIQRNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLGEASSQP-SPTQSVQETVRVRKV-------DVSSVPDHLKEQEDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSS--MIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGK-----------------VKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACPFLR-EKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALSP-KTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITES----FKGIEHSLIEENCGVVVESIQVTLECG--------LGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLIERVEG--------KRQWNLRLDVKKNPVQDKSLLPGDDF--IPEPQMAIHISSGNTMNITISKSCLNVFNNLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEK----------------SDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA--------SHSDSVLVQIDATEG-NKVITLRSPLQIKNHFSIAFIIYKFV----KNVKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVNTVALPDELSYICTHG-EDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGS-------------------------TADVLHS---------RISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSS-----DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQYRSED-------IHVKHPADFRDIILFSFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMS----SFNLSRIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVG-----CEGSSKPFFYNRQDNGTLLSLEDLN-GGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMVLLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWEVK--PKQKWKPFSQKQIILLEQSYQKHQIS---RDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIKRDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQDIDALNAELMETSMTDMSILSFFEHFHISP------------VKLHLSLSLGSGGEESDKEKQEMFAVHSVNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQG--PEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVS--SLRPPRLIHEDGIIRPYDRQESEGSDLLEN-HIKKLEGETYRYHCAIPGSKKTILMVTNRRVLCIKEVEILGLMCVDWQCPFEDFVFPPSVSENVLKISVKEQGLFHKKDSANQGCVRKVYLKDTATAERACNAIEDAQSTRQQQKLMKQSSVRLLRPQLPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A5G2QD22-1", "uniprot_id": "A0A5G2QD22_PIG", "id": "A0A5G2QD22-1", "name": "", "aln": "MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALS--ELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLIVPGAS-IKYDAEKEEKSLQDSKQKELSRIEEALQKAAEK-------------------------------------------DKPKEAKKDTFLEKLATQVIKNVQVKITDIHIKYEDDV-TDPKRPLSFGVTLGELSLLTANEHWTPCILNEAEKIIYKLIRLDSLSAYWNVNCSMSYQG-----TREQILDQLKSEILTSSSVPPNHQYIFQPISASAKLYMNPYAEA---ELKTPKLDWNIEVQNIAIELTKPQYLSMIDFLESVDYMVRNAPYRKYKPY-LPLHNHGRQWWKYAIDSVLEVHIRRHTQMWSWSNIKKHRQLLKSYKSAYKNKLTQTKVPEEIQKQIQDLEK----------TLDVFNIILARQQAQVEVIRSGQK--LRKKSAETGEKRGGWFSGFWGKKESKKK-DEESLIPETIDDLMTPEEKDKLFTAIGYSESAHN---LTLPKQYVAYIVALKLVSTSVTIRENK-----------NVPEILKIQIIGLGTHVSQRPG---------------AQALKVAAKLEHWYITGLRQQDIIPSLVASIGDTASSLLKIEFETNPENSTADQTLVVQSQPVEVVYDAKTINAVVEFFQSN--KGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLIVPQTGFHHE-KSDLLILDFGTFQLNSKDQG----------LQKTNNSSLEEIMDKAYDKFDVEIKNVQLLFARAEENWKKCRFQH---------------PSTMHILQPMDIHVEVAKAMVEKDTRMARFKVSGGLPLMHVRISDQKMKDVLSLINSIPLPQKPSAQTPTPERQISTIPIISDRTKDLLGTPLLLDGVESESDDEYFDAEDGDTQMDKSIKGSGLKKGAEVPNEELINLLLKFEVKEVILEFTKQQKEEDTILVFNVTQLGTEAAVRTFDLTAVSYLRKISLDYHEIQGSKKKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTTFEKTEQTLKVAFSSLNLLLHTQALLSSINYLTTIIPSDGQKMDDTKEVQVSTEKQQKNSALQKVIVSSKDSDIIYFKLFAKLNAFCVFVCDEKTNIAEIKIQGLDSFLSLQSRKQSLFARLEN---IIVTDVDPKTVHKKAVSIMGNEVFHFNLDLYPDATEGDSYTDMSKVDGVVSLNVGCIQIVYLHKFLMSLLSFLNNFQTAKEALSAATAQAAEKAATSVKDLAQRSFRVSINVDLKAPVIIIPQSSVSTNAVVVDLGLIRVQNQFSLVSGEDYSDPPVIDRMDVQLTKLKLSRTVIQPGSCHPDIQLLHPINLELSVNRNLAASWYHKMPVMEINGHLESMNVNLNQEDLNLLCRILAENLGEVTEELNKVEPRVQETGKIKEPLEISTLKQDVRVSQDTLTAGEEEIRSVDIVNMLLKFEIKEVVITLMEKAEKKGKPLHELNVLQLGLEARIKAYDLTAEAYLKKISMRCFEFADSKGEPLHIINSSNATNEHLLKMLLTKADSDGPEFKTTHDNTKQRLKVSFSSLDLVLHLEALLSLMDFLSSAIPSSEPS--KKESALKPLVGESRSIIAKTVSSHTSQDSVFDLKVIAELNAFNIFVCDQKCNIADIRIHGMDASVSVRPKQTDVFARLKDIIVTNVD------LLSIHKKAVSILGDEVFRFQMTLYPDATEGKAYADMSKVDGRLSLKVG--CIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERAASSMKDLAEKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIKVENKFSIVSMDT-SLPPVIDKMDIQLTQLKLSRTILQAGLPQHP---------QHDIEILKPVNMLLSIRRNLAATWYGQIPGMEIKGKLKPMQVALSKDDLTVLMRILLENLGEASSQP-SPTQPTQEAVRVIK--------DVSSKLDHLKEQEDLTDSKLSLDQNVTLQFDFHFESLSVVLYNSDTSQESKLSFHNDNFRLGELRLHLMASAGKMFKDGSMDISVKLKTCTLDDLREGIERATSRMIDKKNGQNDNSS--MIDISYKQGKNGSHVDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENTTKESQIPLRQTALAK-----------------IKMEKDDSVRPNMTLKAKITDPEVVFVANLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACPFLR-ERRGKNITTVLQPCTLFMEKCTWASGKENINVKVEEFTIKISPIILNTVMTIMAALSP-KTKDDESKDTSKEMENLWGVKSISDYNSWFLGVDMATEITEN----FKDIENPLIEENCTVVIESVQVTLECG--------LGHRTVPLLLAESKFSGNIKNWTSLMTAAADMTLEVHYYNETHAVWEPLIERVEG--------KRPWNLRLAVKKNPVQDKSLMPGDDFMVLPEPQTEVNISSGDTMNITVSKSCLNVFNNLAKGFSEGTASTFDYSLKDRAPFTVTNSVGVPIKVQPSHNLKVMGSLEK----------------SDVCDVGAGQSLELEYANVEPSHQGKLSILSRQESSLFTLTFAPHGYTEVAKVPVARPGRRLYNVSNPNA--------SHSNSLVVQIDATEG-NKVITLRSPLQIKNHFSIAFIIYKYV----KNVKLLERIGVARPEEEFHVPLDSYRCQLFIQPAGILESQYKVSTTYISWKEELHRSREVKCILQCPSTEINFLPLIVNTVAVPDELSYICAHG-EDWDPAYIIHLYPTVTLRNFLPYSLRYLLEGTAETHELAEGC-------------------------ASDVLHS---------RISGEIMELVLMKYQGKNWNGHFRICDTLPEFFLVCFSS-----DSAETLTVDLSIHVKRIGSQMELSIFSPYWLINKTSRVLQYRSED-------IHVKHPADFRDIILFSFKKKNIFSKNKVQLKISTSSWSNSFSLDTVGNYGCVKCPANNMEYLVGVSIKMS----SFNLTRIVTLTPFYTIENKSSLEIEVGEIASDGSMPTNKWNYIASSECLPFWPEKFSGKLCVRVVG-----YEESSKPFFYNQRDNGTLLSLEDLN-GGLLVDVETATHSTVISFSDYHEGSAPALIINHTPWDVLTYKQRGSQEEMVLLPRQGRLFAWADPTGTRKLTWSYAANIGEHDLLKDECGQFPYDANIQIHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQANHEINFSLHSLGLSLVNNENKQEVSYIGITSSGVVWEMK--PKQKWKPFSQKQIILLEKSYKKYLES---REHGWIKVDDNFEVNFGKDLMEMRLPFRCPIKRDFLSGIQVEFKQSPHQRSLRARLYWLQVDSQLPGTVFPVVFHPVAPPKSIALDSEPKPFIDVSIITRFNEYSKVLQFKYFMVLIQEMALKVDQGFLGAITALFTPTADPEAERKRTELIQKESDALNTELVETSVTDTSILSFFEHFHISP------------IKLHLSLSLGSGGEESDKEEQEMIPIHSINLLLKSIGATLTDVDDLIFKLAYYEIRYQFYNRDQLMWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGFEALFYEPFQGAVQG--PEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREEMGRQPKDFGDSLARGGKGLLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGAVARPTGGIIDMASSTFQGIQRAAESTEEVS--RLRSPRLIHEDGIIRPYDRQESEGYDLFEN-HIKKLKEETYRYHCAIPSSRKTTLMVTNRRVLCIKEVEILGHMSIDWQYPFEDFVQSPGVDGNLLKISVEKQGLFQKKDSANQGYVQKIYLQDATTAERACHAIVDAQSVRHQQKLMKQSSLKLLRPQILS", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q8BX70-1", "uniprot_id": "VP13C_MOUSE", "id": "Q8BX70-1", "name": "Intermembrane lipid transfer protein VPS13C", "aln": "MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALS--ELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGAS-IKYDAEKEEKSLQDIKQKELCRIEEALQKAAEKGAHSGEFMYGLENLLYKDVKPGRKRKKHKKHFKKRFKGLDRSKDKPKEAKKDTFLEKLATQVIKNVQVKITDIHIKYEDDI-TDPERPLSFGVTLREFSLLTTNEHWTPCILNEAEKIIYKLVKLDSLSAYWNVGCCMSYRG-----SREHILEQLKREILTSTNIPPDHQYIFQPISASAKLYMNPGAES---ELKTPKLDGNVEVQNIAIELTKPQYLSMIDFLESLDYMVRNAPYRKYKPC-LPLHTNCRQWWKYAIDSVLEVHIRRYTQPWSWSNIKNHRQLLKSYKMAYKTKLTQAKVSEEIQKQIQDLEK----------SLDVFNIILVRQQAQVEVIHSGQK--LRKKSAEAGEKRG-WFSGFWGKKESKKR-DEESSVPETIDDLMTPEEKDKLFTAIGYSENAYN---LALPKQYVAHILTLKLVSTSIIIRENR-----------NVPEILRVQIIGLGTQVSQRPG---------------AQALKIEAKLEHWYVTGLRQQDIVPSLVASIGDTTSSLLKIEFETNPENSPADQTLIVQSQPVEVIYDAKTINAVVEFFQSN--KGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLIIPQTGFHHE-KSNLLILDFGTFQLNSKDQG----------AQKTANASLEEIIDKAYDKFDVEIRSVQLLFAKAEENWKKCRFQH---------------PSTMHILQPMDIHVELAKAMVEKDVRMAKFKVSGGLPLMHVRISDQKIKDALCLINSIPLPQKSSTPS--PERQVASIPVLSGGTKALLGTSLLLDGVESESDEEFFDAEDGDSQAARTVKASELKKAAEVPNEELVSLLLKFEIKEVVLELTKQQKEEETILVFNVTQLGTEATMRTFDLTAVSYLRKISLDYHDIKGSRKKPIHLISSSDRPGLDLLKVEYIKVDRNGPSFQTTFEKTEQTVKVAFSSLNLLLQTQALLSSLNYLTTVIPSDSQNTGVAKEVQAMPEKQ-KNSPLQKVMVPSRDSDVIGFRLFAKLNAFCVTVCDEKSNIAEIKIQGLDSSLSLQSKKQSLFARLEN---IIVTDVDPKTIHKKAVSIVGNEVFRFNLDLYPDATEGDSYTDMSTVDGVVALHVGCIQIVYLHKFLMSLLSFLNNFQVAKEALSAATAQAAEKAATSVKDLAQRSFRVSVDIDLKAPVIVIPQSSLSTNAVVVDLGLIRVHNRFSLVSGEDTANPPVIDKMEVQLTKLKLSRTAIQPGTSHPDIQLLHPINLEFFVSRNLAANWYHKVPVVEIKGRLDSMNVSLNQEDLNLLFRILAENLGEATEDLDKGKPRIQERGETKACREVS-TPQDVHTTQGVPAARVEETRPVDIINVLLNFEIKEVVVTLMKKAERKGSPFHELKILHLGMEAKVKAHDMTAAAYLRNISMRCFHFPDSKGEPLRIVNTSDVSDGILLKLLFIKADSDGPDFKTIHDNTKQKLKVSFSSLDLVLHLEALLSLMDFLSSAIPSSDSSSSEKEPELKPLVGESRSLAIRAVPS-SYEGDAFDLKITAELNAFNIFICDQKSNIAEIKIHGMDASISVKPKQTDVFARLKNIIVMNVD------SLSIHKKAVSILGDEVFRFQMSLYPDATEGENYGDMSKVDGRLSLKVG--CIQIVYVHKFFMSLLSFLNNFQAAKEALSTATVQAAERAASSVKDLAQKSFRLLMDIDLKAPVITIPQSSVSPNVVIADLGLIRVENKFSLVSVEQLALPPVADEMSIQLTQLKLARTVLQADSPQH------------DVEILKPVNMLLCIQRNLSAAWYTQIPGMEIKGELKPMQVALSQDDLTVLMKILLENLGEASSQP-SPTQYAQEAARVKR--------DTRSGPDYLKEQ-ELADPKPPGDQTVTLQFDFHFDSLSIILYNSDSSQEPRLSFHNDSFRLGELTLHLMASAGKMFKDGSMNVSLKLKTCTLDDLREGIERATSRMIDKKNDQDNNSS--MIDISYSQDKNGSQVDAVLDKLYVCASVEFLMTVADFFIKAMPQSPENIAKEIQIPSRQTAAGR-----------------VKMEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACPFLR-ERRGKSITTVLQPCSLFMEKCTWASGKQNINIVVKEFVIKISPIILNTVMTIMAAMSP-KTKEDEWKDTPKETDNLWAVKSITDYNSWFLGVDMATEVTEN----FRDSEHPSIEENCVVAVESVQVTLECG--------LGHRTVPLLLAESKFSGNIKNWTSLMAAAADMTLEVHYYNETHAVWEPLIERVEG--------NKPWSLKLNVKKNPIQDKSLMPGDDF--IPEPQTAVHISSGATMNITISKSCLNVFSNLAKGFSEGAASTFDYSLKDRAPFTVKNALGVPMKVQPNRNLKVMGSPEK----------------SDIYDVGAGQHLELDYASLEPSRQGKLSILSRQESSLFTLTFVPYGYTEVASVPVARPGRRLYNVRNPSA--------SHSDSVLVQIDATEG-NKVVTLRSPLQIKNHFSIAFIIYKFV----KNVKLLERIGIARPEEEFHVPLDSYRCQLYVQPAGGLEQQYTHSSTYISWKEELHRSREVRCMLQCPAVEVSFLPLIVNTVALPDELSYIGAHG-EDWDPAYVIHLYPPLTLRNLLPYSLRYLLEGTAETHELAEGS-------------------------SADVLHS---------RISGEIIELVLVKYLGKNWNGHFRICDTLPEFFLVCFSS-----DTAEVMTVDLSVHVRRIGCRMELSVFSPYWLINKTSRVLQYRSEE-------IHVKHPADFRDIILFSFKKKNIFSKNKVQLKISTSAWSNGFSLDTVGSYGCVKCPATNMEYLVGVSIKMS----SFNLSRVVTLTPFCTVANKSSLDLEVGEIASDGSIPTNKWHYVASSECIPFWPENLSGKLCVRVVG-----YEGSSKPFFYNRQDNGTLLSLEDLN-GGILVDINTAEHSTVITFSDYHEGSAPALIMNHTQWDVLTYKQSGSQEELVLLPGETRLFAWADPTGIRKLTWNYAANFGEHDLLKDECGQFPYDANIQIHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQADHEVALSLHSLGLSLVNNENKQEVSYVGITSSGVVWEMK--PKQKWKPFSQKQIMSLEQAYSKRLAS---QDRGWVKLDSNFEVNFDKVPMEMRLPIRCPIKRDFLSGIQVEFKQSPHQRSLRARLYWLQVDNQLPGTMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQFKYFMVLIQEMALKVDQGFLGAVISLFTPTTDPEAERKRTKLIQQDIDALNTELMESSMTDMSILSFFEHFHISP------------VKLHLSLSLGSGGEESDKEKQEMIAIHSVNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLMWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQG--PEEFAEGLVIGVRSLVGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREEMGRQPKDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGAVARPTGGIIDMASSTFQGIQRVAESTEEVS--SLRPPRLIHEDGIIRPYDRQESEGSDLLEN-HIKKLEGEAYQFHCAVPGNKRAVLMITNRRALFIKEVEILGHMSVDWQCLFEDFVCPPEVSENLLKISVKEQGLFHKKDSANIGHLRKIYLKDPITAKRAFDAIESAQSARQQQKLMRQSSVKLLRPQGPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZMR7-1", "uniprot_id": "A0A8I5ZMR7_RAT", "id": "A0A8I5ZMR7-1", "name": "", "aln": "MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALS--ELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGAS-IKYDAEKEEKSLQDIKQKELCRIEEALQKAAEKGAHG-EFMYGLESLLYKDVKP----------------------DKPKEAKKDTFLEKLATQVIKNVQVKITDIHIKYEDDV-TDPERPLSFGVTLREFSLLTTNEHWTPCILNEAEKIIYKLVKLDSLSAYWNVGCCVSYRG-----SREHILDQLKCEILTSTNIPPDHQYIFQPISASAKLYMNPGAES---EFKTPKLDGNVEVQNIAIELTKPQYLSMIDFLESLDYMVRNAPYRKYRPC-LPLHTDCRQWWKYAIDSVLEVHIRRYTRPWSWNNIKNHRQLLKSYKMAYKNKLTQTKVSEEIQKQIQDLEK----------SLDVFNIILVRQQAQVEVIHSGQK--LRKKSSEAGEKRG-WFSGFWGKKECKKR-DEESSVPETIDDLMTPEEKDKLFTAIGYSENAYN---LALPKQYVAHILTLKLLSTSIVVRENR-----------NVPEILRIQIIGLGTQVSQRPG---------------AQALKIEAKLEHWYVTGLRQQDIVPSLVASIGDTTSSLLKIEFETNPENSPADQTLIVQSQPVEVIYDAKTINAVVEFFQSN--KGLDLEQITSATLMKLEEIKARTATGLTHIIETRKVLDLRINLKPSYLIIPQTGFHHE-KSNLLILDFGTFQLNSKDQG----------AQKTTNSSLEEIIDKAYDKFDVEIKSVQLLFAKAGENWKKCRFQH---------------PSTMHILQPMDIHVELAKAMVEKDVRMARFKVSGGLPLMHVRISDQKIRDALCLINSIPLPQKSSTQS--PERQVASIPVLSGGTKVLLGTSLLLDGVESESDDEYFDAEDGDSQAARPVKASELRKAAEVPNEELVTLLLKFEIKEVVLELTKQQKEEETILVFNVTQLGTEATMRTFDLTAVSYLRKISLDYHEIKGSRKKPIHLVSSSDRPGLDLLKVEYIKVDRNGPSFQTTFEKTEQTVKVAFSSLNLLLQTQALLSSLNYLTTVIPSDSQNAGVAKEVQTITEKQ-KNSPLQKVMVPSRDSDVIGFRLFAKLNAFCVTVCDEKSNIAEIKIQGLDSSLSLQSKKQSLFARLEN---IIVTDVDPKTVHKKAVSIVGNEVFRFNLDLYPDATEGDSYTDMSTVDGVVALHVGCIQIVYLHKFLMSLLSFLNNFQVAKEALSAATAQAAEKAATSVKDLAQRSFRVSVDIDLKAPVIVIPQSSLSTNAVVVDLGLIRVHNQFSLVSGEDAVNPPVIDKMKVQLTKLKLCRTAIQSGVSHPDIQLLHPINLEFCVNRNLAANWYHKVPVVEIKGRLDSMNVSLNQEDLNLLFRILAENLGEATEDIDKGKPRIQEIGKTKACQDVS-TPQDVHTTQGVPAARVEETRPVDIINVLLNFEIKEVVVTLMKKAEKKGNPLHELKILHLGMEAKVKAHDMTAKAYLRKITMRCFDFPDSKGEPLHIVNSSDVSDGTLLTMLFIKADSDGPDFQTIHDNTKQKLKVSFSSLDLVLHLEALLSLMDFLSCAVPSPDSSSSETESELKPLVGGSRSLAVKAVPS-SSEGDVFDLKVTAELNAFNIFICDQKSNIAEIKIHGMDASVSMKAKQTDVFARLKNIIVMNVD------SLSIHKKAVSILGDEVFRFQMSLYPDATEGENYGDMSKVDGRLGLKVG--CIQIVYVHKFFMSLLSFLNNFQAAKEALSTATVQAAERAASSVKDLAQKSFRLLMDIDLKAPVITIPQSSVSPNVVIADLGLIRVENKFSLVSVEQLSLPPVADKMSVQLTQLKLSRTVLQADSPQH------------DIEILKPVNMLLSIQRNLSAAWYTQIPGMEITGKLKPMQVALSQDDLTVLMKILLENLGEASSQP-SPTQFAQEAARVKR--------DTRSGPDCLKEQ-DLAEPKPPGDQTVTLQFDFHFDSLSIVLYNSDGCQESRLSFHNDSFRLGELTLHLMASAGKMFKDGSMNVSLKLKTCTLDDLREGIERATSRMIDKKNDQDGNSS--MIDVSYSQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAMPESPENIAKDIQIPSRKTAPGR-----------------VKMEKDDSVKPNMTLKAMITDPEVVFVANLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACPFLR-ERRGKSVTTVLQPCSLFMEKCTWASGKQNINVMVKEFVIKISPIILNTVMTIMAALSP-KTKEEDQEDTAEEKDSLWAIKPITDYNSWFLGVDMATEATES----FRDFEHTQIEENCVVAVESVQVTLECG--------LGHRTVPLLLAESRFSGNIKNWTSLMAAAADMTLEVHYYNETHAVWEPLIERVEG--------KTPWSLKLNVKKNPLQDKSLMPGDDF--IPEPHTAVHISSGSTMNITISKSCLNVFNNLAKGFSEGAASTFDYSLKDRAPFTVRNALGVPMKVQPNRNLRVMGSPEK----------------SDVYDVGAGQHLELEYASLEPSRQGKLSLLSRQESTFFTLTFVPHGYTEVASVPVARPGRRLYNVRNPSA--------SRSDSVLVQIDATEG-NKVVTLRSPLQIKNHFSIAFIIYKFV----KNVKLLERIGIVKPEEEFHVPLDSYRCQLYVQPAGSLEQQYTQSTTYISWKEELHRSREVRCMLQCPAVEVNFLPLIVNTVALPDELSYIGAHG-EDWDPAYIIHLYPPLTLRNLLPYSIRYLLEGTAEAHELAEGS-------------------------SADVLHS---------RISGEIIELVLVKYLGKNWNGHFRICDTLPEFFLVCFSS-----DTAEVLTVDLSVHVRRIGCRMELSVFSPYWLINKTSRVLQYRSEE-------IHVKHPADFRDIILFSFKKKNIFSKNKVQLKISTSAWSNGFSLDTVGSYGCVKCPATTMEYLVGVSIKMS----SFNLSRIVTLTPFCTVANKSSLELEVGEIASDGSIPTNKWHYIASSECIPFWPENLSGKLCVRVVG-----YEGSSKPFFYNRQDNGTLLSLEDLN-GGILVDINTAEHSTVITFSDYHEGSAPALIMNHTQWNVLTYKQSGSQEALVLLPGETRLFAWADPTGTRKLTWSYAANFGEHDLLKDECGQFPYDANIQIHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQADLEVALSLHSLGLSLVNNENKQEVSYVGVTSSGVVWEMK--PKQKWKPFSQKQIMLLEQSYQKHLTS---QDRGWIKLDSNFEVNFDKVPMEMRLPLRCPIKRDFLSGIQVEFKQSPHQRSLRARLYWLQVDNQLPGTMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQFKYFMVLIQEMALKVDQGFLGAVIALFTPTSDPEAERKRTKLIQQDIDALNTELLESSMSDMSILSFFEHFHISP------------VKLHLSLSLGSGGEESDKEKQEMIAIHSVNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLMWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQG--PEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREEMGRQPKDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGAVARPTGGIIDMASSTFQGIQRVAESTEEVS--SLRPPRLIHEDGIIRPYDRQESEGSDLLEN-QIKKLEGEAYQFHCTVPGNKRAVLMITNRRVLFIKEVEILGHMSVDWQCLFEDFLCPPGVSENLLKISVKEQGLFHKKDSANVGYLRKIYLKDPITAKRAFEAIESAQSARQQQRLMRQSSVKQ-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8V1A109-1", "uniprot_id": "A0A8V1A109_CHICK", "id": "A0A8V1A109-1", "name": "", "aln": "MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALS--ELDVPFRIKVGQIDKLTLKIPWKNLYGEAVVATLEGLYLLIVPGAS-IKYDAEKEEKYLQDNKQKELARIEEALKKAAEKGAHSQDSLYGLESLIYKDTKPGRKRKKYKKHFKRPFKGRDHSKDKTKEEKKDTFLEKLATQVIKNVQVKITGIHVKYEDDI-TDPQRPISLGITLGELSLLTTNENWKPSILNDATKVIYKLLCLDSLSAYWNVHSKMYYHG-----SHEQILDQLKGGIPHGDNQPQDYQYIFRPVSASARVFINPNAEV---ELKTPKLDCNVEVQRIAIELTKPQYLSMIDLLESIDYMVRNAPYRKFRPN-VSVHKNARQWWKYAGDSVLEVHIKRCTRMWSWSTIKQHRQLVKTYRTIYRSKLTLGKLSEETQRQIQDLEK----------KLDVFNIVLARQHAQLETIRSGQKV-LKKKATEVEKKSGGWFSGFWGRRESKKKEDEESFVPETINELMTPEEKAKLFTAIGYSESSYH---LSLPRQYVAHIVTLKLVSTSLTIKEDK-----------NVAETLKVQIIDLSTKISQRPG---------------AQAIKVEAKLENWYVTGLRQENIVPSLVASIGDSRSSLLKIEFNINPEESTADQSLSIESQPVEIKYDARTINAMVEFFQTS--KGMDLERLTSATLMKLEEIKERTATGLAHIIEMRKVLDLKIHLKPSYLVVPQTGFYHE-NSNLLILDFGTFQLNSINQGN---------SEASSFSSLEEIMDKAYDKFDVEIKNVQLLFGRAGEDWKKARFQR---------------SSTLHMLQPMDIHIQLAKSMVEKDTRMAKFKVSGGLPLVHIRVSDQKIKAIFDLIDSIPLPEMSSVSI--PSTKAATIPAIPVDAKGLLTTHHLLAEMASDSEEEYFDFEERYEPYYRALSKGEEIENTESAKEELTDLQLKFEIKEVLLELTKQEKTEETVLVFDVKHLGTEATVRTFNLAAVSYLKTISLDYYEIGG-KKVPLHLISSSDKPGLDLLKVEYIKADKNGPHFLTVFDNTEQKIQVAFSSLNILLHTEALMSAVSFLATVSPSGS---GSSRETPTKEEKQQDDRTLKKVTRPFKDKDAFAFKLLARLDAFCLNLCDEKKNIAEIKIQGLDSSLLLQSNQTEFFARLKD---VVVTDVDTRTLHKKAVSIVGDEVFSFSLVLYPYATEGEAYADMTKVDGTVSLKVGCIQVVYLHKFLVSLLTFLNNFQTAKEALSAATVQAAEKAATSVKDLAQRSFRLAMDIHLKAPVIVIPQSSVSFNAIVVDLGLIKVQNRFSLASPEGSLLPPIIDKMDVQLTKLKLSRASMEEGLSHQDIQILHPINLSLSVSRNLAASWFHKLPILEITGYLDTMNVAVSQEDLNVFLKVLTENLGEAEQTN--AKQILQEEGRIKG-MEKSTLMQSKGVSEGILSEKRKETLNEDVINVLLNFEIKEVVITLMKQLQKERYPLHILNVLQLGTKTEIRNHELTAGAYLKKIIMRCTEITDSNGDPLCIINSSSKTDEPLLKMEYIKADADGPDFVTTYSSTKQNIDVVFSCLDVVLHTEALISIMSFFTFSVPSGALPSTDKAPENKPQTEEKGSVFRPASGS-TTHDDTFELKLTANLNAFSISVCDQTCRIADIRIQGMDASVAVKTKEIEVFSRLQDIIITNVD------PKTIHKKAVSIMGDEVFRFQMSLYPDATAGEAYADMSKVDGKMSLKVG--CIQIVYLHQFFMSLLNFLNNFQTAQEALNAVTVQAAEMAASSMKDFAKKSFRLLMDINLKAPVIVVPESSTSCNALIADLGLIRVQNEFKFVSSDESSLPPVIDNMDVQLTHLKLSRCILSADSQPD-------------SEILCPVSLTLLVQRNLAATWYHKAPTIGIKGDLKPMQIALSQDDLTVVMKILLENLGGASSQPNTMQQSIEDNQMVRKE-------KVPNESDISEGQENISTSQSSAECYTVLIFDFNFESLSVTLYRSDMNQKPLLSLHNEKLCLGELRLNLLASSGKILTDGSVDVSVKLKACTLDDLRAGIQNVTARMIDKK-DNTNDSS--MIDVSYKQDKNGTEVVAILDKLYVCASMEFLLTVADFFINSMPTSSP--ERSTQLHLKNVTSVK-----------------SKPETEAPFRPNMKVKAVIMDPEIVFVANLTSADAPALKVSFQCDFSLTSGKHAQRMTAQVKDFKVLACAFLR-EKQDRSVTKVLQPCSLVMENMMHVSGLQTVVLTVEELTIKISPIILNTVVTIMAAIKP-KTTEEDSKGAAEVPEDLWQVKPIDECNAWFLGVDVATEATET----FKDHEHAVKQEKFDIVVKSVQITLECG--------LGHRTVPLLLAESVFSGVLKNWSSLMEVSADMSLEIHYYNETYAVWEPLIERIEGG-------KKQWSLKLEMKTNPVQERSLMPGDDFIVFPEPQTAVNISSKDTMNITISKCCLAVFSNLAKAFSEGTASTFDYSFKDTAPFIVKNALGVHLQVFPSSSFRIVNSAEK----------------ENVHCVESGQNMELEYSVFEAPQRRRLSALYRQESSIFSLSLELERYEKVINVPIAKPSRRLYNIKSLSD--------GHSDSIIVQIDATEG-NKVITVRSPLQIKNHFSIPFVIYKLN----RDSRLLQPIGISKPEEEFHVPLHSYRCHLYVRPTGMLEGQFRESTTNIAWREELHRSNEVKCLLQCPATETNFLPLIVSTTAVPDQLNYISAHG-EEWDPAYIIHLHPTLTVRNLLPYSLRYLLEGTAEARELLEGS-------------------------AADVFHS---------RINGEIMELVLMKYQGKNWDGHLKIHEGMPEFFSVCFTS-----HSATVMTVDLYVHTRRIGSRMILSVFSPYWIINKTSRILQYRAED-------THVKHPADLRDIVLFSFKKKNIFSKNKIQLCISTSTWSSSFSLDTVGSYGCVRCSANGMEYLVGVSIKMS----SFNLTRIVTFTPFYTIANKSSLELEVGEIGPNGSFPTNKWNYISPSECLPFWPENSSGELCVRVVG-----FESVSKPFLFQVPDNGTLLRLKELT-GGLLVEVNVSQHSILISFSDYHEGAAPALIVNHTSWDSLRFKQSGLQEEMELKPKQVCLFAWTDPTKTRKLTWGYSQSFGEHDLLKDECGQFPYNANTQIHWVSFLDGRQRVLLFTDDVALVSKALQAEELEQPDQEIILSIHSLGLSLVNNENKKEISYIGITSSGVVWEEK--RKQKWRPFNQKQINVLEQAYQKYLCKTAFQTPGWHKLDSTTEVNFSKVPMEMRLPVRCSIRRNFLSGIQVEFKQSPHQRSLRAQLYWLQVDNQLPGSMFPVVFHPVAPPKSIALDSEPKPFIDISVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLAALSELFTPSTDPEAERQRSKLIQQDVDALNTELMETSLTDVSMLSFFELFHISP------------IKLHLSLSLASGAEASDKGE-EMIAIHSLNLLLKSIGATLTDVDDLIFKLAFFEIKYQFYKRDQLMKRAVRHYSEEFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPFQGAVQG--PEEFAEGIVIGVKSLLGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREEMGRQPRDFSGSLAKGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRVAESTEEVP--NLRPPRFIHEDGIIRPYDRVEAEGYDLFEKLHIRKLENEKYRYHCVLPRGKRANLIVTNRRVIYVKEVEILGHLTAEWDYLFEDFTCRPTCEESVLKLTVSDPRMFQKKGSTGHVCVKAVQLQDEATAKSVCIAIEEAQATRKQQKLVKQASLRLEKPQMLS", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "A1Z713-1", "uniprot_id": "VPS13_DROME", "id": "A1Z713-1", "name": "Intermembrane lipid transfer protein Vps13", "aln": "MVFEAVVADVLNKVLGDYIENLDRNQLKIGIWGGDVVLQNLKIRENALD--ELDLPVQLIYGYLGKLVLKIPWKNLYSQPVIVNIEDLYVLVSPNNN-VQYNAEKEAKYEMDLKKAALDALEAARKKELEMD---------------------------------------------QPKADAGFAEKLTAQIVNNLQVQITNVHLRYEDTT-TTG-SPFSFGISLHELELYTTDCDWEKCYMAQQASQVFKIANLSCLSAYLNCGGQLYANN-----KSD--LSQQFKTNIACKETKPNYNYVLGPISCNAKLKLNMNPELDDPPFEKPKIDLTLEMEKLNVGLTNTQFDNLMKLGDAMNRQQLGIPYRKYRPYNIPYKGHARDWWHFAITSILEEEVRKPRESWTWGHIKTHRERCNTYAQKYKEQCLSKKPSAVLTETCRLLET----------ELDVFNLLLIRQRVNIEIAK--------QREAVPEQKSGWFSGWGWGGGAKKDDQTTSQKLVEKFEAAMTSEEKEKMYRAIGYQENAKP---TDLPESYEAIRMNFKLIALEVGLYKDERNSSAATKDFHELPSLVLLNFSMATALITQRPA---------------AEAISIIAGMREIKVTGLTRNDYTPLLVESKITDEFNLLEVFFETNPLDKLCDQRVKVVARPLQITYDAPTILALINAFQTP--GDVTLSKFEDAASTKISNFKERSATGMQYMIDKKAVLDVDILLMPNILVVPHKGVYDAGNVSLLVVSMGQVHLSSQPRRESNKLQHLFSAGEDKDEILKTVMENAYDRFTVAVDDVQMLVVRAGEPWQNALAEAN--------------STEMHVLRPVSLKVTAALCVVDNDPRLPNIKVDIDLPAILVNVSEDRIFLAIKVATSIPLPEQKEPAS-----------------------RLTQTNSRSSMSISNFINKEVKKIGPSASGSSASKDPLLDEIIQYTSLDVNFSLGEINFVLFQSSRKCETSPDVSIEFLTPDGDVLPSQLTEN----------------IQEPIEELPPTPPQQILSIDIRRLEAH------------------------------------------------------------------------------------------------FVSKTYESVATVKLG--DINLRQYDCQDSDMDVLDV---IYTPKQENSSNYLFTVSCT-----------IADKSSPEFSTKYNSTEQLVVANFEVLQIVLHQECLQRIMEVVNNFQRNLDLVLSSTRPRDRMGSIGGGDGIKR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLNVILEDTEEIMTTDQMKRRKKTRR-----------------------------------------------------------------------------------------------------------------------------------------------THVVETVKVRVIANLDQVGLVLTGRKRPIAEMNVKKFVSSLIIKSSYTEVNIGLKDIQVLDLN------PYTIHKNILSIVGKDAFNCQIVIYNKEE----TQDYNSDDMKITVDIG--CMKIIFLNWFVAGVMNFLNNFTAAQATISQAGAAAAESARQKAMDAYETATRMKLNIRIKAPIIIVPIGSQDRNALLLDLGLLELTNNTVEVAVAEEERLAVIDEIKLQICDVKISKIVLLDGNESTVDEVDAEVGFLSKFNMMNPMSCTLSITRNLSYTWYRDVPELNLSGRLKSIELTLFADDYALVMLVLNRNLNEGLEEFPPSEEAPQEAQVRPE----------RRNSRAGRLSRTVQVSPIREKIHESIKFNFQFDGVVINLMEGEGAGLARFGIYFLSVKGTKLDNGTLSTSVVLCNIQMDDMRSNSKSQIRQYLSRKDWVQPKLDTDEIIDACYNERNFMVDVTAIIKEDDTFAEVRVRGFDLIVCIDFLLKLTTFLTLPPEENPRESVYIKPAPVSETARDTKHSIRSSAILAAQELVPVESSSHEVPNRKMNLILHIDEPDIILVENLEDLNTSCIIFNAQVHLNYRSINDKQIVNGQIDALKMYMCAFLP-ERREMTRHYILHPCVISLQGSTPEEEGMHISLKLSDIIINVSPATIELLNKAMLSVSSGTMTKCAIAEESRNYSNLWHQHHFHSRTYWFTKVEQGVDALEAEQRSVSTDNEKQKTEKCVIEIPSITLVIESG--------VGYYTKPLISLDTRITAVFNNWSRSLTAHGSLTLNMNYYNQALAEWEPIIELNEVIGRNGVREYTPWELKFEMGMEKVQSELEDDAEQQ------AMHMNIHSAETLEITLSKTCLGLLSELAEAFSQAIDQNGLTKPDIVAPYVLENDTGFDVNLNLRKGIFTLHEVHRGGTPVGANSTLLMVAQSEEVDPSVIKTCTISTGGRAYLQTKDLSTLSEEDSEDYTLYVTIGDINKEIALPVSKSDTRFFNLMRSTS--------HEPWGIISEVKQEYG-TTKVNIHGVVSVHNHFTTGLNIYRRNPAPTAQCFEDIFVGRVRPGEVFHVPLHAIYAESKDLFFSMRG--YRRSVQGISWASNPSDLN-YSHQLHCDPTNT-FEPLIMNARRSKSEVYFENTNKYTLLSAFYTIHLRPPLYLRNSLPINIQVSVAGCSVRKEDGLDAQSSQRFVDRGYRKEDFLDYGEKPVNSGDVLHLPTVRLASKGKESKSFLVVRLVQYLEKDWSCATEIWDYTDDVITWTFSSY----DSEMKVDMDLYVKTENRHGSLMLTLFSPFWMINKTGMMLTYKSETT----SVEVLYHPPEYSGPILFTFRDKLFFDKKKASIRIDNGQWSEKIPLDVAGSVGEVICFANNQKYPVGVHNHLT----QNSLTKQITFIPFYIVCNKCHFDIELQEQ----SRPADPWLHLEPNEMEPLWPRN--DTKNNLVVR-----VDGKITPAFDFTEVICTLLKLEDSKYGGINVDVQTTEGGVYITFTDYKPADAPGLLINHTG-KQIVYHEKGTKNEHILNAKSTIMYAWDDPTGPKMLVFGTNK--EETDLKRDGIGEVIMQDGGKVLWVSFLDGLQRVLLFTENESIANRTESTASLQSITQSIDLRIHGIGLSVINNETGLDILYLGVTSSGIIWESKKVTKNRFKELTINENALLEIEYQKYLVHKSVNDVQTYKLDNKFPIDFD--LMILKKTVERNLRRSFYPAIWLSRKSSPFQSQLHVKINRIQVDNQFLDPIFPVVLAPIPPPKSVASTTSLKPFIECSMVQRIMPNSTVRQFKYARILIQEFLFKVDLNFLTAIAEMFAKEVSDEAAAKQFRQDVESIELPLSAFFEEHSLEE-QKSFYDNLHLGP------------LKIHVSFSMAG--------SDTKALPGFLGSLVQGVGVTLTDVNDVVFRLAFFEREYQFFSQKQLINEITSHYTGQALKQLYVLVLGLDVLGNPYGLVVGLKKGVEDLFYEPFQGAIQG--PGEFAEGLVLGVKSLFGHTVGGAAGAVSKITGAMGKGLAALTFDEDYQKKRRQGIQNKPKNFHEGLARSSKGLVMGFVDGVTGVVTKPVTGARDNGVEGFFKGLGKGAIGLVARPTAGVVDFASGSFEAVKRAADASEDVK--RMRPPRFQHYDFVLRPYCLMEATGNKIMKETDKGKFATTDNFIHCEEIIQKSEYLVVTNYRVMYVQRNEMFGVWTSLWSYLWNEISSVAATARGVQFTVKTDGKKVLGLFSSKESPRKLVLVADERKRDALVDIIESQRSDPNPLRATIAYPAHN-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07878-1", "uniprot_id": "VPS13_YEAST", "id": "Q07878-1", "name": "Intermembrane lipid transfer protein VPS13", "aln": "-MLESLAANLLNRLLGSYVENFDPNQLNVGIWSGDVKLKNLKLRKDCLD--SLNLPIDVKSGILGDLVLTVPWSSLKNKPVKIIIEDCYLLCSPRSE-DHENDEEMIKRAFRLKMRKVSEWELTNQARILSTQSE-----------------------------------NKTSSSSSEKNNAGFMQSLTTKIIDNLQVTIKNIHLRYEDMDGIFTTGPSSVGLTLNELSAVSTDSNWAPSFIDITQNITHKLLTLNSLCLYWNTDSPPLISDDDQDRSLENFVRGFKDMIASKNSTAPKHQYILKPVSGLGKLSINKLGSTE----EQPHIDLQMFYDEFGLELDDTEYNDILHVLSSIQLRQITKKFKKARPS-FAVSENPTEWFKYIAACVINEIHEK-NKMWTWESMKEKCEQRRLYTKLWVEKLKLKNLEAPLRDPIQEAQLSELHKDLTYDEIILFRSVAKRQYAQYKLGMTEDSP-TPTASSNIEPQTSNKSATKNNGSWLSSWWNGKPTEEVDEDLIMTEEQRQELYDAIEFDENEDKGPVLQVPRERVELRVTSLLKKGSFTIRKKK-----------QNLNLGSIIFENCKVDFAQRPDSFLSSFQLNKFSLEDGSPNALYKHIISVRNSSKDQSSIDNHATGEEEEEDEPLLRASFELNPLDGLADSNLNIKLLGMTVFYHVHFITEVHKFFKASNQHMETIGNIVNAAEATVEGWTTQTRMGIESLLEDHKTVNVSLDLQAPLIILPLDPHDWDTPCAIIDAGHMSILSDLVPKEKIKEIKELS-PEEYDKIDGNEINRLMFDRFQILSQDTQIFVGPDIQSTIGKINTAS-------------STNDFRILDKMKLELTVDLSILPKAYKLPTIRVFGHLPRLSLSINDIQYKTIMNLIANSIPSMIDDEEN----------------------------NGDYVNYSSGSEKEMKKQIQLQLKNTLKALENMQPLQIEQKFLELHFDIDQAKIAFFQCIKNDSRNSEKLVDILCQRLNFN--------------------------------------------------------------------------------------------------------------------------------------------------FDKRAKEMNLDLRVHSLDVEDYIELTDNKEFKNLIS---SGVEKVTRSQKDLFTLKYKR-----------VQRIVPHNDTLIELFDQDIVMHMSELQLVLTPRSVLTLMNYA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLTFTDPNAPEMPADVLRHNKEDRD--------------------------------------------------------------------------------------------------------------------------------------------------DAPQKINMKIKMEAVNVIFNDDSIKLATLVLSAGEFTMVLLPERYNINLKLGGLELTDETN-ESFSRDSVFRKIIQMKGQELVELSYESFDPAT------NTKDYDSFLKYSTG--SMHVNFIESAVNRMVNFFAKFQKSKVSFDRARLAAYNQAPS-----IDAVNNMKMDIVIKAPIIQFP-KLVGTQENNYDTMRFYLGEFFIENKFSVIDESHKINHIKLGVREGQLSSNLNFDGSSQQ-------------LYLVENIGLLFNIDR--DPLPQDDTPELKVTSNFESFALDLTENQLTYLLEISNKVSSAFNITDENSGESGGKGEIKSPSPDPASLSSESERTATPQSLQGSNKSNIKNPEQKYLDFSFKAPKIALTLYNKTKGVTS-----LNDCGLTRIMFQDIGCSLGLKNDGTVDGQAHVAAFRIEDVRNIKDNKHTELIPKSKNKEYQFVANISRKNLEVGRLLN-ISMTMDSPKMILAMDYLVSLKEFFDAIMSKSHENNLYYPENTNQKPENKA----------------IVESVQEGGDVTKIQYSVNIIETALILLADPCDMNSEAISFKIGQFLVTDQN----IMTVAANNVGIFLFKMNSSEEKLRLLDDFSSSLTIDKRNSTPQTLMTNIQLSVQPLLMRISLRDIRLAMLIFKRVTTLLNKMTEKEDNGEEEESTDKIQFSHEFERKLAVLDPSILGERSR---ASQSSDSESIEVPTAILKNETFNADLGGLRFILIGDVHEMPILDMNVNEITASAKDWSTDFEALASLETYVNIFNYSRSSWEPLLEMIPIT------------FHLSKGHSEMDP---------------AFSFDILTQRIAEITLSARSIAMLSHIPASLTEELP---LASRVSQKPYQLVNDTELDFDVWIQDKTTEDN-------------------KNEVVLLKANTSLPWEFEDWRSIREK---LDIDKSKNILGVCVSGQNYKTIMNIDATTEGENLHVLSPPRN--------NVHNRIVCEARCDENNVKIITFRSTLVIENTTSTEIELLVDS----KDPNKPSLKYAIKPHQSKSVPVEYAYDS-DIRIRPASEDIYDWSQQTLSWKSLLSNQMSIFCSSKEDSNQRFHFEIGAKYDEREPLAKIFPHMK---------IVVSASMTIENLLPADINFSIFDKREEKRTDFLKTG----------------------ESMEVHHIS----------LDSFLLMSVQPLQDEASASKPSIVNTPHKSPLNPEDSLSLTLSGGQNLLLKLDYKNIDGTRSKVIRIYSPYIIMNSTDRELYIQSSLLNIAQSKILLENEKRYTIPKMFSFDKEDDKS-NRARIRFKESEWSSKLSFDAIGQSFDASVRIKNKEQESNLGINISEGKGKYLLSKVIEIAPRYIISNTLDIPIEVCETG---SMDVQQIESNITKPLYRMRNIVDKQLVLKFLGG-----DSNWSQPFFIKNVGVTYLKVLKNSRHKLLKIEILLDKATIFIRIKDGGD-RWPFSIRNFSDHDFIFYQRDPRK----------VSDPYKDDQSNESSSRSFKPIFYRIPSKSIMPYAWDFPTAKEKYLVLESGTRTREVRLAEIGELPPLRLDKRSKDKPAP-------IVGLHVVADDDMQALVIVNYKANVGLYKLK----------TASATTTSSVSVNSSVTDGFVQKDEDEKVNTQIVVSFKGVGISLINGRLQELLYINMRGIELRYNESKAYQTFSWKMKWMQIDNQLFSGNYSNILYPTEIP-YTEKEIENHPVISGSISKVNDSLQAVPYFKHVTLLIQEFSIQLDEDMLYAMMDFIKFPGSPWIMDSRDYKYDEEIQLP-----DVSELKTAGDIYFEIFHIQP------------TVLHLSFIRSDEISPGLAEETEESFSSSL-YYVHMFAMTLGNINEAPVKVNSLFMDNVRVPLPILMDHIERHYTTQFVYQIHKILGSADCFGNPVGLFNTISSGVWDLFYEPYQGYMMNDRPQEIGIHLAKGGLSFAKKTVFGLSDSMSKFTGSMAKGLS-VTQDLEFQRVRR-LQQRINKNNRNALANSAQSFASTLGSGLSGIALDPYKAMQKEGAAGFLKGLGKGIVGLPTKTAIGFLDLTSNLSQGVKSTTTVLDMQKGCRVRLPRYVDHDQIIKPYDLREAQGQYWLKTVNGGVFMNDEYLSHVILPGKELAVIVSMQH-----IAEVQMATQELMWSTGYPSIQGITLERSGLQIKLKSQSEYFIP-------------ISDPEERRSLYRNIAIAVREYNKYCEAIL------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q54LB8-1", "uniprot_id": "VP13A_DICDI", "id": "Q54LB8-1", "name": "Intermembrane lipid transfer protein vps13A", "aln": "MVFEGLVSDVLSRVLGEYVKNLNKDQLKIGIFGGSVQLQNLELKEDALANLPINLPITVKKGFLGKLDLKVPWKDLKSKPVIINIDCIYALAVPQTQNYKYDEKEEAKKQAELKKKKLENYEWIKSIKDAEENE---------------------------------------ISSLQSEKSDSFTDRLVTKIIDNLQIVINKVHIRFENKN--DIGKLYALGITLDKLSIQSTDEFWIPSFVDSSKSKFIKKLALMDSLGFYIDDNADSLQN----LKLDEFTKAFTSLIPSSASFSLLSKYIIKPISSQLKLNINKSDIIEK---SIPKILVECVMSQITCTLSSGQYQNILSILNFTNEYLRDIKYLKFRPI-VKVSENPKLWWRYVG-QVIVEQIREKRFSRSWEFIAQRRRARLAYIPLFKRNIPKVDWLQPLNKHELEQLN------QLEERLSFEDIVYFRSLAYAEIKKETEKNKIRKQFLDSKRQERGFFQNIFNTKKDEDE-------KAAPKIQLSSEERDELYKTIEYNDVVSAS---EEPPDWVKIIGNFEIKGFAIQLVEAN-------------QVFIEALYTGLSLKFEQRNE---------------GIKVMAGIHLFEVYDQFTKRTHFPKIIASVPTKGTGTFASVIVDTRPPDKNLDLSVELNMDPLNIIVTKPLIMKVVDFFHDP---NLDITNISNRAGAHLEDIKEQAKMQLQDAIDNHKVLGLAVNIHAPVIFIPEDVINER--SNILIVDLGKLVVRSDTSAF---------VKGSNKLAGSTSEIDLYDKFNVSFESIQVLLSDDLKSAISTGDKKPPTIGGVNDKQGHPLKHHNSIIKKFDIQLKIFSSIQQNNLTMTKLKIKGELPKFDFYLSDKKFKQLLTILNAITADIPVTSGK-----------PKATITPINDSNSPSSVSPKLISTSPHSFSSSSAPVDVNSSNDLKKSKENIELLLNAKLVEAEFEIKSISLTLSNNQSDLIRVVFSDINVGFQQRTFDMSGTFKLSSLEIEDCFTKNTLNKLATSNPPHADRSLGKDSLVQMHFKQIQTASPEFNKIDMSIDLKIHSFYLVINPSTIYQLLKLAKSLQKDPENIDQISKAYPRLLSRNKVVP-----------------------INSSEGGGTAATSPNAHLSSPNQQSPNQQSPNQQSPQIVSRKIITGTGSNSKPVGPDEKVVSSKTASGTTTRRVIIRSVRHVPKKKGPTEFVSMKFSVHINSLGLALNQDNNELLGIFTINNVSTDVSMFKDNRMLVQGRLGSIILDDLTPTISN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YKQIIIPKNTSGDMLDFKYETFSMTLSNYAGYDASVN--------------------------------------------------------------------------------------------------------------------------------------------ANVKSILFNANVGFLIHLQNYFLGGMLDPILKQDDSNNNNKSIEKSKSIDSKLNEQQSSSSSTSTPRSDDNHEKSERELDLEKNKKLLTSLQQNTNKHIPKMKLDIVVETPVLVIPQATRSKNSLIMELGKIIISNGWQYHDKTMAPMENMKIHLQDANITILSDNRSSYFLEKLTIDLGISKFLVPNTDPEVEDQTIDLSISHFAFYLDENQYRFFLGLSQNVQKELDLANKEVQEIKKLSNMGDP-----------FEMGRITSNDMQYFTEQEVIQKMGKVLLRIHLVLDYVSFKISSLDAQGEIAHFIVRGIDVDVKNTDKNKTNIQLSMKSILLS--------DTRSNSTNIFKNLLENKVNTESVAPFLQVGYIRDNLLGDQYINVN--INNTCLFLSPTPLLMISEFFMVPLSEQHDTNNMDVDLDLDLESLESELNSLMDPSIEKDDNDLQQQQQQSSSSSFIPSQQQQQQKVRSQSIIGQNRSRTSSIGGKESKTISSSISNNSLSSYPQEAGMEDEEEKEI-----------------FRSPTITFTATLVPSVTLVEDETLSTTRCLMLKTRVGVQFRRDPHGIENATVVIENTKVNIYKPSSTESENQGSRPIQILKPIEMITIKYIKENLTSTEWKQDIGISCTAMKVFFSYDDVKAILKILNNITTNLQKQQEQQKKRQLSFDNMASSSTSLPSLNKSTNSFQTSTSGNSNSGKKDEELFTNNEKLRFSCPNVSVLFINES-------PEMYIPIIELFFADIEASAMNWSTDLESKASMSIKGDYFNETNMKFEPVIEDWSFS------------VDLKKNRTGKIKGSFLATRELLNINVSHSLLQTISSAMIHVEKIDQMDAANLSSSLNASNLTTSTGSNNSSTSGSGLVQSFNGPSVLNKYLPGGEKNDSKIS--------------FHSHWISNQTGVTLEYHIPKVDSEMFQLTESSEPVSLPMKISKSRDATMGEHLNIELFIQGSKISNLSMDAVGYRIYRIGSTNEFITCEVRLRPDGSKCCYIKSMDQFENNTSLNLELKCQE-------NGSPFSIAKHSKFSLPILVSKDLCKFWIKLE-----NSPYWSDPIDIYKLPDHENSKLFKLQTVDKVGMFVSLVHKTIANRNCDRFNNTFK-----------FFPPIQIENILPYPFKLSIPGTTIDKVNMGSG------------------------EKIDCHYYQ---------PGSNLVAIVSELENFPETKHTLVSGDATSPTFTKTFKLQ----QNNREISLDIERTELIKG-VRTLSFYCQYWLVNNSLLPIEVKLSDNQ--VLLVPPNLPDQLPRPPVLYSNNTIRARIPLQAEQPMNKSFCEKFPISAVGNPNTIFLTNPTRTYELSYKVDFCPNE-RFRLSKTVTFVPKNVICNDLPFPILVAQCVSTIDGIDKMALNFSGSGLSSSSGSNGKGVSNPVRLLGELRLDPGEYKPFHWEENVENKKISIRPITNEKNPQEWRWSGGFFVDSISDYVVKSRNTERPDHDSLLFHVNIKEKQGTHFIRIPLSSKESPPYIIQNDTQFKISFFQRDSPENIDYIEPKEKLCYGWDEPSAEYVLSVAVEGKTLKKRINVNKIKGYKLQHERTDLYITITIDGPSRVLLFSTNEKKFRSIKAWTDNKAVNLS-----------------------------------QSQSEYHFNIRCSGIGCSIIDKTPKELAYISMKDFLIIATQSSIENTVEVKLAELQIDNQLIKTDFPVLIHTVSPDKEHRKDFLHAVIIKSTIDN-------IDYFRYFSTLIQEMTIELEDHWIKEVLDFVDSIPSFGRGNNASNNNNNNGMTSSQMRQSGSGLDSLTSTLYNAVSIEPPTSDSSTIKMVYFALLVLNPIKINLTLALQNDGLIKSNHKILSLVEGLGLSLTRLDRAPITLQGLLMEHPFTSRSTIIDKIKTSYIQQALRQFYNILGSVDFLGNPVGLFRNFGTGVHDFFVEPAQGLVKS--PADFTKGLAKGTSSFVKNSVFGTFNTLSKLTGTLGTGVATLSFDEKYLQERKLHQARKPSHVGEGLAMGGIGLGRGILQGITGIVTKPVEGAKKGGFAGFAKGLAQGVVGVAVKPTTAVIDLATKTTEGIKNTTNLQSQAER--VRPPRCFSHDNVLRPFDEVESEGWFLLKTAHKGKHASDSYIWHHIIN--QECTIIISDHRIILSKSKKNFLHSSFLFQIPFKFIKSNEMVDDGVLLEFDPPQNLGLLDRDVKS---KVIPVDDPNVNMLLNMKLSHALKKFHDNNPNLSNSSSIKY-----", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*.:.:::*.:.**.*::*:: .**::**:.*.* *.**:::::.* :::*. : * :..* *.:**..* .:.* :: * * * . : : : * * : * . . . * : *.::::.*:*: *. :*:::*: :.*::* ::. ::: * . : . * * : . : . :*:: *:* :: :* . *:: ..: * . :: .:: . . : : * :* . . *::: :: .. :* : : . * : : . : . : *. . : : . .. . :: *:: ::: :* :.: * . : . : : . . ** . : : . : .: .* : * : : : : : : . *: : .: . : :. . :: : :: : .:.: : : . :.:* :: . . . :*:* : . *::. : :: ..:.: .: : :. ::: ** . . :.: : : : . . : : .*.: . : : : : . . : : : . . : . : : : : . : :: : . . . . .: :. . . . : . .. : . .. :.: .. . . : : . . : :. : . . : .:. : . : * : . : .* : * . . .: : . :: . : . : : : .: : : : : . : ..: : : : : . : . : . . : . . : . : . : : : : : . . . : : : : .* :. : :.. . . . . . * . . : : . :*: : ..: . :* :**::* . : .. : .: . :: . . : . . .. . : . .: : : : . . .:. ..* : : : :. : : : . : . : . . ..: :.* ** :. : . : : : .:: : : :.: : .:. : ::*.: : : . :: . :.. :.:.. *. . .: *:: : : * : * : : : : . . . * :. : :.* :. . . : . . : . : . : . :: . . : :. : . : : : : : : : ..* . :: :*:*.*: :. :: . .*. :: : *:: ****: :::: : : :. . :. . . :: . : * : : . : :. .. :* :: . : :: * : : *:: :: . * :*** **. : *. :* ** ** : . * :: :. * *: ::* * . :*::**::..*:: :: * .: : *: . . .** .. .: . *::*: .* . :. * ** **:.:* :* .:.: ..:*::: :.:: .: . :* ** * :::*: *: * :: . * . :: : : :. : : .: : * : : ", "identical_positions": 149, "similar_positions": 681, "identity": "3.71%" }, { "cls_id": "homologset.oma.816352", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A4A2-1", "uniprot_id": "A0A8I6A4A2_RAT", "id": "A0A8I6A4A2-1", "name": "", "aln": "--MVFESVVVDVLNRFLGDYVVNLDQSQLSLGIWKGAVVLKNLVIKENALHELDVPFKVKVGRIGSLQLKIPWKNLYTQPVEAVLEEIYLLIVPSSRIQYDPIKEEKQLMEAKQQELKRIEEAKQKVVDQENPREEKQDTFAEKLVTQIIKNLQVQISSIHVRYEDDITNREKPLSFGISLQNLSLQTTDQYWIPCLHDDTEKLVRKLIRLDNLFAYWNVNSEMFYLNDYDDALEALKNGIVNENIIPEGYDFVFRPISANAKLQMNRRSDFDFSDPKINLDIELHTIVIEFNKPQYFSLMELLESIDMMTQNLPYRKFKPSVP-----LHLHAEEWWAYAIHGILEVNVCPSLRMWSWEHIKNHRYKMKQYREFYKKKLTNKKPSP----EILMSLEELEKTLDVFNITIARQQAEVEVKKAGYKIYKEG---------------LKDPEDN------AGWFSWMWS-WSESNANQQQ-DVKPGILAEMLTPEEKALLYEAIGYSETAVDPTLPKTFEALKFFVHLKSMSIVLRENRQKPELLNVVVEGLSTSIVQRPGAQALKFETKIDSFHITGLPD---DFKKPHLLSSLDD-MSLFRITFEINPLDETVSQRCTIEAEPLEMIYDARTVNSIVEFFRPPKDVRLAQLTTATLTKLEEFREKTATGLLYIIETQKVLDLRINVKASYVIVPQYGNFSPTSNLLLLDLGHLKVTSKRRSGLPDVKPSGASLEDIMH------RAYDSFDIQLSSIQLLYSRVGDNWKEARKLNVSTQHILIPMHVNIELSKAMVFMDIKMPKFKIFGKLPLVSLRISDKKLQGIMELLESIPKPEPVTDVSAPARSFQIQAS-TMPVSHISQKLIPLLEQS-ATEDDSEEEFFDAPCSPLEEYPQVSCRVESTRRKKLQKKDGSMNFIQLSMRFEVAEVLIQFYHLVGDCELPVLEMGVLGLGTEVEIRKFDLKGNAFLKELWLKCPGYLDEHKKPVYLITTLDNTMEDLLTLEFMRVEKNAPNLNSTYNNVLQLIKVNFSSLDIHLHTEALLNTMNYLNNILPELGETSASVSAAEP---EDKGDIIKKLALKLPTNEDIITLQLLAELSCLRIFIQDQKQNISEIKIEGLDSEMIMKPLVTEINAKLRNIIVLDSDKMAVYKKAVYITGKEVFSFKMISYMDATAGYAYTDMS--------------VVDARVY---LTVGCIEVVFVTKFLYSILAFINNFQAVKN---ALAEATVQAAGMAADGVKELARKSSRFALDVNIKAPVVLIPQSPVSRNVFVADFGLITIKNIFVTVTETQSNIPPVIDLITIKLSKMRLYRSQFMNNTYQEVLDLLLPLN-----------LEVIVERNLSWEWYKEVPCFN--IKAQLKPMEFILSQEDLTTVFQTLYGNIWYGRDVPAPSSVNKGPEIMTTEVTS-TSYHSG-ATMVTSAVVEVHPQASPANTTLNVSFQTDHLIMTLYSPGPDQASFTDVRDPSLELAEFKLENIISDLKVYTDDS----MVFSFSLKNCILDDKRP-----HVMKATPRMIGLTVGFDKKDMVDVKYRQIRDVFVTDVVVQEMYVCASVEFLMTVARVFFDAYMTST-----ALETSVQTWTTR-EAPVQELRKWEMNILIKNPEIVFVADMTRNDAPALVITTQCEICCKGEPESNTVTAAIKDFQVRACPFLPVKRKGRVTTVLQPCDLFYQATQFGTDPQTIDISVKSLTLKVSPVIINTIITVTSALYTTKETVPEESTSNVAHLWDKKDTKNLKMWFLEESNETEKVVPTDEVMPGGETLNLNIDSIFIVLEAG-IGHRTVPMLLAKSSFLGESKNWRTLINLHCQLELEVHYFNEMFGVWEPLLEPLEIDQSDDFRPWNLGIKMKKKAKEAIVESDSEEENYKVPEYKTAISFFSRDQLNITLSKCGLVMLSNLVEAFTEAATGSSAVFLRDLAPFMILNSLGLTVSVSPSDSFHVLNVPLAKSYELK---------NEESLSMDYVRTKDNDHFNAMTSLSSKLFFILLTPANHSVADKIPLTKVGRRLYTVRHRESGVER-----------------SIICQIDTVEGSKKVTIRSPVQIKNHFSIPISVFEGD------TLLGIASPENEFNIPLASYRS-SLSLKPEDEDYQLCEGIDFEEIIKHD---GQLLKKKCRSISPSKKSFVINIVPEKDNLAS---------------LSAYSEDGWDLPYVMHLWPPILIRNLLPYKIAYYLEG-IENTVCTLSEGHSSQIYNVEMDQAKLHLKLLDYLNHDWKS---------EFQIDPNQQDINFINFTCLTEMEKSDLDIAIHMTYNTGQTVVAFHSPYWMVNKTNRMLQYKADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQL--MVTDSELSDQFSIDTVGSHGAIKCKGLKMEYQVGVTIDLSSFNITRIVTFIPFY----MIKNK---SRYHISVTEEGSDK------------------WLSLDLEQCIPFWPENASDILLIQVERSEGPPKR------IYFNKQDSCILLRLDNELGGVIAEVN---------LAEHSTVITFSDYHEGAATFLLINHTKSDPVQYNQSS---LSEIEDSLPPGKAVYYTWADPVGSRKLKWS--CGQSYGEVTHKDDMMTPISVGKKTIYLVSFFEGLQRIILFTEDP---------------RVFKVTYE-----------------------------SEKAELAELEVVLALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKSRWKPMSVKHTEKLEKEFREYTESSPLEDKVVELDNSIPVLLTPSGNDMKILEPHVIAVRRNYLPALKVEYNTSAHQSSFRIQIYRIQIQNQIHGAIFPFVFYP-----IKPPRSVTMDSAPKPFTDVSIVMR---------------SAGHSQISRIKYFKVLIQEMDLRLDLGFVYALADLVPKTEVTEKTEVEYFHR------DVEAFEQEFEVVSSVDQSQVNLFEYFHISPIKLHLSVSLSSGRDEAKDTEQHGGLIPVHSLNLLLKSIG--------------------------ATLTDVQDVVFKLAFFQLNYQFHTTSELQSEVIRHYSKQAIKQMYVLILG-------------------------------------LDVLGNPFGLIREFSEGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITSAMAKGVAAMTMDEDYQQKRREAMNKQPAGLREGITRGGKGLVSGFVSGITGIVTKPIKGAQKEGAAGFFKGVGKGLVGAVARPTGGIIDMASSTFQGIKRATETSEVES----LRPPRFFNEDGVIRPYRLRDGTGNQMLQVMEN------GRFAKYKYFT----HVMVNKTDMFMITRCGVLFVTKGTFGQLTCEWQYTFDEFTKEPFIVHG------------------------RRLRIEAKERVKSVFHAKEFGKIINFKTPEDARWILTKLEEAREPSPRL--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5H8C4-1", "uniprot_id": "VP13A_MOUSE", "id": "Q5H8C4-1", "name": "Intermembrane lipid transfer protein VPS13A", "aln": "--MVFESVVVEVLNRFLGDYVVNLDESQLSLGIWKGAVALKNLVIKENALHELDVPFKVKVGHIGSLKLKIPWKNLYTQPVEAVLEEIFLLIVPSSRIQYDPIKEEKQLMETKQQELKRIEKAKQKVFDKEKPREEKQDTFTEKLVTQIIQNLQVQISSIHIRYEDDITNGDKPLSFGISLQNISLQTTDQYWIPCLHDNTEKLVRKLIRLDNLFAYWNVNSEMFYLNDYDESLKALKNGIVNENIVPEGYDFVFRPISASAKLQMNRRSDFDFSDPKINLAVDLHTIAIEFNKPQYFSLMELLESIDMMTQNQPYRKFKPSVP-----LHLHAKEWWAYAIHSILEVNVCPSLRMWSWEHIRNHRYKMKRYREFYKKKLTSKKPSP----EILMSLEELEKTLDVFNITIARQQAEVEAKKAGYKIYKEG---------------VKDPEDN------AGWFGWLWT-WSESNANQQQ-DVKPGILEEMLTPEEKSLLYEAIGYSETAVDPTLPKTFEALKFFVHLKSMSIVLRENHQKPELLNVVVEGLSTSVVQRPGAQAIKFETKIDSFHITGLPD---DFKKPHLLSSLDD-TSLLQITFEINPLNETVAQRCTIEAEPLEIIYDARTVNSIVEFFRPPKDVHLAQLTSVTLTKLEEFRAKTATGLLYVIETQKVLDLRINVKASYVIVPQYGNFSPTSNLLLLDLGHLKVSSKRRSLLPDVRPSEASLEDIMH------RAYDSFDIQLTSIQLLYSRVGDNWKEARKLNVSTQHILIPMHVNVELSKAMVFMDIKMPKFKISGKLPLVSLRISDKKLQGIMELLGSIPKPEPVTDVSAPARSFQIQAS-ALPVSHISQKLIPLLEQP-VTEDDSEEEFFDAPCSPLEECPQVSCRDKCTRQKKLQKKDCVMNLIQLRMRFEVAEVSIQFYHLVGDCELPVLEMGALGLGTEAEFRTFDLKGSAFLKELWLKCPEYLDENKKPVYLITTLDNTMEDLLTLEFMKVEKNAPNLNSTYNNVLQLIKVNFSSLDIHLHTEALLNTMNYLNNILPELREKSASVSAAEP---EDKGDIIKKLALKLPTNEDIITLQLLAELSCLQIFIQDQKQNISEIKIEGLDSEMIMKPLVTEINAKLRNIIVLDSDKMAIYKKALYITGKEVFSFKMISYMDATAGYAYTDMS--------------VVDIRVH---LTVGCIEVVFITKFLYSILAFIDNFQAVKD---ALAEATVQAAEMAADGVKELARKSSRFALDVNIKAPVVLIPQSPVSQNVFVADFGLITMKNIFVTVTETQSNIPPVIDLITIKLSKMRLYRSQFRNDTYQEVLDLLLPLN-----------LEVIVERNLSWEWYKEVPCFN--IKAQLKPMEFILSQEDLTTVFQTLHGNIWYGQDLSAPSSANKDPETMTSGVTS-PPDHSP-ATVVTAAVVEVHPQASQAHTMLNVSFQTDYLTMALYSPGPDEASFTDVRDPSLELAEFKLENIISSLKIYTDDS----TVFSFSVKNCILDDKRS-----HVMKATPRMIGLTVGFDKKDMVDIKYRKIKTFVVTDAVVQEMYVCASVEFLMTVAHIFFDAYMTST-----ALETSVQTRTTR-EAPAQELGKWEMNILIKNPEIVFVADMTRNDAPALVITTQCEICCKGEPTSNTVTAAIKDLQVRACPFLPVKRKGKVTTVLQPCDLFYQATQLGRDPQMIDISVKSLTLKVSPVIINTIITITSALYTTKETVPEENTSNIAHLWDKKDTKNLKMWFLEESNESEKVVPTNEVMPGGETLNLRIDSIFIVLEAG-IGHRTVPMLLAKACFSGESKNWLSLINLHCHLELEVHYYNEMFGVWEPLLEPLEIDQTDDFRPWNLGIKMKKKAKEAIVESDSEAENYKVPEYKTAISFYSRDQLNITLSKCGLVMLNNLVEAFTEAATGSSSVFLRDLAPFMIFNSLGLTVSVSPSDSFSVLNVPLAKSYELK---------NDESLSMDYVRTKDNDHFNAMTSLSSKLFFILLTPANHSVADKIPLTKVGRRLYTVRHRESGVER-----------------SIICQIDTVEGSKKVTIRSPVQIKNHFSIPISVFEGD------TLLGIASPENEFNIPLASYRS-SLSLVPEDQDYQLCEGIDFEEIIKYD---GQLLKKKCRSTNPSKKSFVINIVPEKDNLAS---------------LSVYSEDGWDLPYVLHLWPPILIRNLLPYKVAYYIEG-IENTVVTLSEGHSSQIYNVEMDQAKLHLKLLDYLNHDWKS---------EFYIRSSQQDINFINFTCLTEMEKSDLDIAIHMTYNTGQTVVAFHSPYWMVNKTNRMLQYKADGIHRKHPPNYTKPVLFSFQPNHFFNNNKVQL--MVTDSELSDQFSIDTVGSHGAIRCKGLKMEYQVGVTINLSSFNITRIVTFIPFY----MIKNK---SKYHISVAEEGSDK------------------WLSLDLEQSIPFWPENASNILLIQVERSEDPPKR------IYFNKQDNCILLRLNNELGGIIAEVN---------LAEHSTVITFSDYHDGAATFLLINHTKSDPVQYNQSS---LGEIEDSLPPGKAVYYTWADPVGSRKLKWS--CGQSYGEVTHKDDMMTPISVGKKTIYLVSFFEGLQRIILFTEDP---------------RVFKVTYE-----------------------------SEKAELAELEVVLALQDVGISLVNNYTKQEVAYIGITSSDVVWEAKPKKKARWKPMSVKHTEKLEKEFREYTEASPLEDKVVELDN-IPVRLTPSGNDMKILQPHVIPVRRNYLPALKVEYNTSAHQSSFRIQIYRIQIQNQIHGAIFPFVFYP-----IKPPRSVTMDSAPKPFTDVSIVMR---------------SAGHSQISRIKYFKVLIQEMDLSLDLGFVYALADLVTKAEVTEKTEVEHFHK------DVEAFEQEYEVVSSVDQSQVNLFEYFHISPIKLHLSVSLSSGRDEAKDSEQHGGLIPVHSLNLLLKSIG--------------------------ATLTDVQDVVFKLAFFELNYQFHTTSELQSEVIRHYSKQAIKQMYVLILG-------------------------------------LDVLGNPFGLIREFSEGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITSAMAKGVAAMTMDEDYQQKRREAMNKQPAGLREGITRGGKGLVSGFVSGITGIVTKPIKGAQKEGAAGFFKGVGKGLVGAVTRPTGGIIDMASSTFQGIKRATETSEVES----LRPPRFFNEDGVIRPYRLRDGSGNQMLQVMEN------GRFAKYKYFT----HVMINKTDMFMITRRGVLFVTKGTFGQLTCEWQYTFDEFTKEPFIVHG------------------------RRLRIEAKERVKSVFHAKEFGKIVNFKTPEDARWILTKLEEAREPSPRL--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RL7-1", "uniprot_id": "VP13A_HUMAN", "id": "Q96RL7-1", "name": "Intermembrane lipid transfer protein VPS13A", "aln": "--MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVGHIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEEAKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQNLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIVNENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIMELLESVDMMAQNLPYRKFKPDVP-----LHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQKVKQYKELYKKKLTSKKPPG----ELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG---------------VKDPEDN------KGWFSWLWS-WSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPD---NSEKPRLLSSLDDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNSIVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMD------RAYDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTFKIRFEVPKVLIEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQSEEKSAPVSTTET---EDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAGSAYTDMN--------------VVDIQVN---LIVGCIEVVFVTKFLYSILAFIDNFQAAKQ---ALAEATVQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLN-----------LEVVVERNLCWEWYQEVPCFN--VNAQLKPMEFILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYSATSGVTTNASHHSGGATVVTAAVVEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQASFTDVRDPSLKLAEFKLENIISTLKMYTDGS----TFSSFSLKNCILDDKRP-----HVKKATPRMIGLTVGFDKKDMMDIKYRKVRDGCVTDAVFQEMYICASVEFLQTVANVFLEAYTTGT-----AVETSVQTWTAKEEVPTQESVKWEINVIIKNPEIVFVADMTKNDAPALVITTQCEICYKGNLENSTMTAAIKDLQVRACPFLPVKRKGKITTVLQPCDLFYQTTQKGTDPQVIDMSVKSLTLKVSPVIINTMITITSALYTTKETIPEETASSTAHLWEKKDTKTLKMWFLEESNETEKIAPTTELVPKGEMIKMNIDSIFIVLEAG-IGHRTVPMLLAKSRFSGEGKNWSSLINLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEENYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAFTEAATGSSADFVKDLAPFMILNSLGLTISVSPSDSFSVLNIPMAKSYVLK---------NGESLSMDYIRTKDNDHFNAMTSLSSKLFFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVER-----------------SIVCQIDTVEGSKKVTIRSPVQIRNHFSVPLSVYEGD------TLLGTASPENEFNIPLGSYRS-FIFLKPEDENYQMCEGIDFEEIIKND---GALLKKKCRSKNPSKESFLINIVPEKDNLTS---------------LSVYSEDGWDLPYIMHLWPPILLRNLLPYKIAYYIEG-IENSVFTLSEGHSAQICTAQLGKARLHLKLLDYLNHDWKS---------EYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNKTGRMLQYKADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQL--MVTDSELSNQFSIDTVGSHGAVKCKGLKMDYQVGVTIDLSSFNITRIVTFTPFY----MIKNK---SKYHISVAEEGNDK------------------WLSLDLEQCIPFWPEYASSKLLIQVERSEDPPKR------IYFNKQENCILLRLDNELGGIIAEVN---------LAEHSTVITFLDYHDGAATFLLINHTKNELVQYNQSS---LSEIEDSLPPGKAVFYTWADPVGSRRLKWR--CRKSHGEVTQKDDMMMPIDLGEKTIYLVSFFEGLQRIILFTEDP---------------RVFKVTYE-----------------------------SEKAELAEQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLEREFKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAHQSSFRIQIYRIQIQNQIHGAVFPFVFYP-----VKPPKSVTMDSAPKPFTDVSIVMR---------------SAGHSQISRIKYFKVLIQEMDLRLDLGFIYALTDLMTEAEVTENTEVELFHK------DIEAFKEEYKTASLVDQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIG--------------------------ATLTDVQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILG-------------------------------------LDVLGNPFGLIREFSEGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMDEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGVGKGLVGAVARPTGGIIDMASSTFQGIKRATETSEVES----LRPPRFFNEDGVIRPYRLRDGTGNQMLQVMEN------GRFAKYKYFT----HVMINKTDMLMITRRGVLFVTKGTFGQLTCEWQYSFDEFTKEPFIVHG------------------------RRLRIEAKERVKSVFHAREFGKIINFKTPEDARWILTKLQEAREPSPSL--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1P8BEE1-1", "uniprot_id": "A0A1P8BEE1_ARATH", "id": "A0A1P8BEE1-1", "name": "", "aln": "MLEGYVQGFVNLLLGYLGRYIKDIQKDQLKISLWNGEVLLENVELNPEAFEYLQLPIALKQGRVGKLSIKIPWKKLHRDPVTIMIEDVFICASQRNDQEWSSDVVEKREFAGKKAKLASAELAKLSRRVFDNP---GGNSYMSYITAKILDSVQVSIKNFHILYSDAQPESGQ-VVLGLRFSSLTVTKQNS-VGPSVGRVRGGQVNILVEVEGLEIYCDMYEGNMDFPSVNEKIGFDN--WCQSRLQSNRFGYLLKPVHVSVTLLVNRSGELYDDLPQYSISAELTDVVVTLNEFQLQQILILLDYLQTSQLRERYGRYRPCSTSLSRKPPGWQKLWWHYAQNSVLSD-VRKKLWKTSWRFLEQRMRIRRRYINFYKIKLDLLLREQSIDKSIRLGLEELEKKSDIDDILSYRSAAEGEMQEACSELTVNMGATGATRSEKEQSAPEKEPSDDPTLNKSRGWLNWLSRGMLGAGGTEDSSQFSGVVSDEVVKDIHKATKFYPLSSSPRNTSATGKICTCSIRLNVRKFSATLQHISGSSSQVITELDILGVIVECKSWKDSTAMILSVISGRLVYPHNGKEILTMKRVCSQSDTLETKPSYGARLELS-KDHDVALSLKATLQPLEAAYDGGFILAVSNFFSGSRYFKLQHERILSSLNGLESETRLAAKAEYLLSSRNKVKWDLDIKDLTLSFPG-RLVESESYNLVLVLESLSITSSSTDALSQIPRLQSDVDHVVNSLQSSVEALDAFQVKDLYDHFDIKICNLEMKLMKIHPFQELPLVEKSSLLIKFASCIIPEESILKQLEVEATLPMFNVHFSPSIFKGVMSVIEYLDIQDHGTRNPPPSPAPIFHFTIKTDLAFLRLHVNLENKGENSTVLVLSIQQLDLWYS-RAIFEEWSVRAKTLEITACSSKDAADSHILCSSGNLLKSSSHGHGMDAHTSDETNIIDYRTTPEAAISLNCKVSQSKSFIFHKYTVYWRSAELHCYP-YIFGLLTNFLDKIASYKISSSYTNPSSLATDTIAPTEIPQFDFERFGFSNFTESRSCGCIPLDKFPFVTINNSGSLHSLESSLCYSTSDWRKLFILKNRKDGAQIGLNCECNSCTFQLKRDCPLNGLASSRDLGQTNHFTVDMHVFNTNVHFHDSSSVFGTIILPVSRYFLNISDDLLDLVASAEDLMLVSSLFTNYSGGFLWKQSSTDVSQVLNLRVRKRGLEPSGSQLEVSIGIQHTYCILPPEYLAIIIGYFSLSDWTSKSGLQSLPQATELTKAHSEFAISYKIEILDSSIVLPVEGDDRRQLKVDIQQLYISFIPECALSNVVQHIPQECVIPLNQVLGRADCLNIFGRDLSVSLLLSESDISTFKKNAVCRSITLAASIIADTWIRFPCDHNPLTELACVMSRVDVCEIVVDDSDALDGFKAFLDVVDQLSLVDEESKLFVSDVPQ--FLHTKMRLKQELSVAPLEPSTSFIKFRIFVNLLTSKLHRLRKAPGTLLSEPVLQADMKFVCSGELKNNFPMSLDVQFFKIGLYSLLSSVMLARCINADGDPSALRVRFTEQAENEYDLCFSLPSLDIWLHFFDWIEVIELLKSYSQKLEDSSEDRFFSKGSKLDMDESIGVVRTICDNTDRVLNVLQTEVSENSSEVMSFAARSENIGVKIHIPLCTSHTEFPGFMATDVHEISEE------EHTNCFKGNYCKYVSVTACSRSGELSILGRDVKLSYKIEKLNG---ILAISGVDTVRSCSLFGAAQLLVETSIQMDQNKIMSIDVGILSDKVEMHASHQVLSFWHGITFDAP--ETPSSQNSEGNMSIKVQIRDVSLLISDGKWGCSGMLLEVLMRNFLLQANLAEKNMESLVSCDLEVNYNNMHKVLWEPFIEPWNFD-IKLSRKFDANSLLNNAGLTEVIVASSNQLNLNLTESLFECIFRIIEMLNILELMETDAIPDNKGLSVYCTNSTRTERYSPYVLQNLTSLPLGYQVFQGHDSDVLNISAPVAQNFVQPGCSVPIYIDNSDTLLIPDRRRSQFGCSSSESGDAIHHYMKVQLDGTSFASPPHSMDRIGLSYFEVDFSKTSNSSDNVEKASKSGYGSSFVVPVVYEVSLQQQSKLIRVYSTVIILNSTSMPLELRFDIPFGISPKILDPIFPGQEFPLPLHLAKSGRLRWRPLGDSYLWSEAHSISKVLSQDSGIGFRRSFACYPCHPSHEPFRCCISVQSTSLPASFHINDLSAGNFGQQLHNLDQSREQFIHQVTLSTPFVVSNCLPDPISLSIESGGITQTASLPEGETPFHHIDPSHDLVLEFKLNGCRTSSLKFSRSETFSTEAKFSGGKFSQIETISFDSHVGGGSVYVSCEKTMDATCGAREVLIFVPFLLYNCTG-TPLIVSDCTNETKGIYSVIPSCYNLIEQHFVQSRKVGLGILTSEKDLLDKAVMEDIPCS-PSSSECSNTASSTERFIDKHATQSTRQVPFAAYPKDSAIVRKRSLSSKSLREVCFQGNDESGKVKACIYSPCPISRVSDTMIRVKRDLPGWVNSSSPYPLWSAPFPLVPPSGSTNVVVPQPSPGESSLLSVTCSILGGALAGRTQAITFQPRYIICNSCSHNLCYKQKGTNLVSHLAVGQHSQLQWTDTTRELLVSIRLNEPGWQWSGSFLPDHLGDTQLKIWNYVNKAFNMVRVEVQNANMSSGDEKIVGSVHGHVGTNFILLSDDDMGYMPYRIDNFSNERLRVYQQKCETFDTIVHPYTSCPYAWDEPCYPHRLTIEVPGDRVLGSYAFEITKQPIAVHLRSTSEKPERTLLLSICAEGATKVFSVVDSGYHAIKDIK-ETFDSRFHEKGKKKLQTDNIIRYTETFLLVLPSIG--ISLVNSHPQELVYACASNVVLELSQSVDQQKLSFQISSLQIDNPLQNSSYPVILSFNHDHEVIPPDWGMKNNKAILLSEIVQQVRGNSCDAVVYVDLAKWRKKDVSLVSFEYINIRIGEFGLELELQTLLSLLEFVKAVLPNSQARLLPLSDPTLRPLIYDTGSKDISSEDTPHARNIPVFNKNQRSIVALPIVVPIGAPWQHIHLLARRRRKIYVETFDLAPIQFTLSFCSAPWMLRNGILTSGESLIHRGLMALADVEGARIHLKQLTIAHQITSWESFQEILVGHYTRQILHEIYKVRTGKMSLFHLVFLFPRALILFPIYLLDVFLQCTITQVFGSAGVIGNPMGFARNVAFGIKDFLSAPSRSISKSPAGIIQGMAHGTTSLFSSTIYALSDAATQFSKAAHKGIVAFTFNDHDVAR----MEKQQLGEGS----RSKGVIGEVFEGLTGLLQSPIRGAEKHGLPGVISGVAMGITGLVARPTASILEVTGKTAQSIRNRSRIHNIRSQRHRLRLPRPLSREQPLRPYSWEEAVGTAVLMEVGDSLKFKGEKLVKCKALKQEGAFVVITGRLVLVLSSLSLVDFRKQGFLGVPIDLVWNIEREIGLESVIHTDCSGGVVRIIGSNSDGVWNWRQDQQKKSSPTKKRWNNPSAQPLLQTNLEFPSEEEAEDLLSVLLSTIETGKSRSWHSRFVLSRSNIT", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .*::* :** *: ::: .**.:.:*:* * *:*: :: :*: *::*: :* *::*.*.: ****:*: :** ::*:::: . ::.. **: : *: :* * ** . :: ::: . :.::*:..:**.*..:*: *.* .: : : :*: :..::: . :. *.: *. *:.::.* * :: . : : . :: : : :..: .: :.::::*: ....* :** .:: . *: .: :* :.: :*: * .:: **: :: . * :::* . . ** ** :.:*. * * **..:.:: ::* ::** ** .: :.******. *: :* *. ** * ::* :: : *:*.*: **:.*: . .::. :.. *::. .*: : .:. * ...* :::: *: * :: .. .. : :: : . . . .: *: :.. . : . . :: *. : . :*:. :. *: :*** **. : :: :** .: .:* : : : * . : *: *::.::: :. :::* : .* ... * *:* * *.::*. . *.:: :.:..::. .* *:*::: :: . . : : : .. :: . ::::..:: : : :::: ..**:..:::* . ::*:*.:: : : * ..* : :: : : : :: : : . : :* * : . : . ..:* . : . . . .: . : : .:. :..:*: . : : * *:. * * ::.: : : .* ..* : :: :.:*. :.: .**: *.:: :.*..: : *. ...* * : ** .: * *: .: . ::: : .::. : * ..: : : *.:::: : . .: . ..:::.: : .. :*: . *:: :* * . :: . : :: : :: * :*:: * ::. : ..**:: *.:*:. :*: * . . : ...: : * .. : : .* *.:: . : : :.***. . .: : .: : : ..** : :. *. : * :. .:* * : . . : .: *. *: :*. :.. : : : :.: *. * :**. :. . * .: : :*: *.: . *. : .** * . :. : : . .* ..: . *: : :. : . *:: .:. .*: . :.: :: . : ::. :. . .* .: . . :* : ::.: *.:: * **. : * .:*. : .. . .*.*.:: : : .* *: : . : :* . . . * . ::. ** :: :. : :: : . : *.:*. : . .*: : . :::.* .: :::. * * : : : * :.: . :: :***:* * :***::** ::* . * :: . ::: . :: :..: * ::.* * : *** .: .* :. : : : : : : .** : . .... :. *:*:.: * ::* : * .: . .: :. : : :: : . .: .: ::* : * . ::. . .:: ::. : ** : : *.* * * *:*:.: . .:*. * :** :** :* : * .:.* .*. .:.:::. * * . * . **::.* * :. .*.: * .:. :: : : * .*::: * ** :: :*. . . :*.**.:. . *.:** . . . * . .:*. :.* . . . :. * . * * :. *: : * *. :* :..: * :.: :**.:..** * :.::.:* :: :: : . . .: : .. *: : : ** *.* .: ::::: *: .* :*.*: : ::: :* * : :* * .. . **. . :..:* . *** :* . : :* .: :.*: . : : . :*:.::: * .*. . * : .* :*. :** ::.. * : : . .:* : * . * : *:* :* **:: . * . . *.. . :: * :.: * .. * * : : .:: . :. . .: ::.:. : *.:: .*:* : . *:::. . : *.. * :.:::.* : . : :* . *..*..: :** :**:* ::.: :*.:: : ** :. . :::: :* . .: ::*::: * *:.* *:* : :* ::: . ..::.: : :: .:: . . . :: ::: : * : * : *.:.: :. : :. * *.:::* .: :*:**:.. ::* : : :*: : ..:*. :: **::* ::::* : * .*:***:*: *:.: *:: *: * :. :.* :::*** * .:*...:: .*:.**:::: * **:.*:*:::. : *:** * . .**::. ...*:**:: .**:**:* * .*.:.**. *:.* *:***..*::::..* *.*:. :. ::.* ** ** :..: :*** .:. *. :* : : ::.* * :. .*::. ::::: .:: . * * :. : :.::. ::* :: :*:* :. : . ::* : *:*. :*: * .: *.. ", "identical_positions": 469, "similar_positions": 1255, "identity": "13.17%" }, { "cls_id": "homologset.oma.816353", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GHP9-1", "uniprot_id": "A0A8I6GHP9_RAT", "id": "A0A8I6GHP9-1", "name": "", "aln": "MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGLIGKVTLQIPFYRPHVDPWVISISGLHVIGAPEKIQDFNDEKEKLLERERKKVLLQALEERWKSERRQQKGESYWYSVT------ASVVTRIVENIELKIQDVHLRFEDGLTNPSHPFAFGICIKNVSMQ-------NAANEPVQKLMRKKRLDVAEFSIYWDVNCTLLG--DLPQAELQEAMARSMESRSHHYILEPVCASALLKRNCSKEPLRSRHSPRIECDIQLETIPLKLSQLQYRQIMAFLKELERKERQVKFRKWKPKVAVSKNCREWWYFALNANLYEIREQRKCCTWDFLLHRARDAVFYTDRYFNKLKGGVLSADDKEEMCRIEEEQSFEELKILRELVHDRFYKQEELAESLREPQFDSPGASPGDPDGSGGS-GMLQYLQSWFPGWGGWYG--QQSPEGKVAEGLTAESHEHWMPEDILGTEEFFDPTADASCMNTYTKRDHVFAKLNVQLQRGTVTLLHQERGAAHANESAFMQLEFSDVKLLAESLPRRNSSLLLVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTASEDRSDQYSAADPDNPVFEMLYERNPVHSHFERRLHVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFTFKNPVLVVVDLGRMLLTNTQEDSRRKSGDDSASEENQFSDDEYKTPLATPPSTPPPETNSSNGEKTPPFSGVEFSEEQLQAHLMSTQMYERYSLTFMDLQVMVGRVRDNWKRVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPETKPSD--TQFREKIFPQEGPRGSLQDSVMNLTQSIVMLEQHTREVLVESQLLLAEFKVNCMQLGVESSGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGPNVAFQTDVAT---LNDQSATTSVSLEKILTKEQESLIKLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDDVSPQPLMTDLERSIMEQGTVQSTYEQNTEVAVEIHRLNLLLLRTVGMSDGERHGRKIATASIGGTKVNVSMGSSFDMNGSLGCLQLMDLTQENVKNQYVVSIG--------NSIGYENIVSDIGYFESVFVRMED-ASLTEALSFTFAEKSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRSMLKSAATKVTTVLATKTAEYSEMVSLFETPKKTRDPFVLEENEIYGFGLPSPRSDTVKLILNINIESPVVSIPRRPGSPELLVGHLGQIFIQNFVAGDDESRSDRLQVEIKDIKLYSLNCTQLAGRDGAGPEVSRAFCPPSGSASVSSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERETELTFSLSPDELGTSSIMKIEGKFVNPVQVVLAKHVYEQVLQTMDNLVYSEDLNKFAASAPPSPCPNSP-LPPLSSCGEPTAEKKENGLFSHSSFSSASQKSLSVKESKAFTQIQANFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALRSLLMEDLLEKNPDSKYKSLMVSRGAPKPSSLAQKEYLSQSCPSVSCVEYPAMPRSLPSHMEEAPNVFQLYQRPISTCRKKQKEVQDKSYPQTPPPSPSVDEPKVLVGKSKFDDSLVHINIFLVDKKHPEFSSSYGRINRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMKVPPEGPLQNVKAEATASMQSELQEPVNSKLDLKVHSLSLVLSKATSELAKANVSKLVAHMEMIEGDLALQGSIGSLSLSDLTPHGDLYRERFTTSGEEALIFQTFKYGQ-PDPLLQREHDIRVSLQMASVQYVHTQRFQAEVVAFIQHFTQLQDVLGRQRAAVEGQTVRDQAQRCSRILLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFAGFPGTFSLQDK-ESVPSASPTDTMKHSMKKMPSTEDPKGPQVQGLFMMPPAGMGLGSLKSDFVPSASIKQRGQQAVPPISQSSSSPEDHVCLLDCIVVDLQDMDIFAAERHPREGSKASESSSGDLIFPSYFVRQTGGSLLTEPCRLKLQVERNLDKEISHTVADISVHGSLSSVHCSLDLCKYKLIRGLLENNLGEPIEDFMRPYDLQ-------------DPRIHTVLSGEVYTCMCFLIDMVNVSLELKDPKGKEGTGSLARFDFKKCKLLYESFSNQTKSINLVSHSMMAFDTRYSGQKPSHGMTNVFNCIFQPSKSSSATQGSIQIELHFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDVKKQN-VTPARYRNASSESAVVPKTVKSGVVTKRSSLPVSNERHLEVKVNVTGTEFVVVEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSCRLGNEQDTALSIVDPVQIQVELVGNSSYQNSSGLMDAFNSEDFPPILEIQLQALDIRLSYNDVQLFLAIAKSIPEQASAAAPDSAALEADS----VSSNLPGASRIGEDVREGSRHTLDPVLELQLARLQELGFSMDDCRKALLVCQGQLKKAASWLFKNAEPLKSLSLVSSS-RDNQGAMSAPRISGVEVKAESVCICFIDDCMDCDVPLAELTFSRLNFLQHIRTNPE------------GYAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKRRLDINITSVLIDQYVSTKESWLADYCKEDKETESAKTEDWMGSSVDPPCFGQSLPLVYLRTRSTASLTNLEHQIYARAEVKTPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGAFLDDTHNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFRYAAPDKNSSSSTIGSPSSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKVITVRSALIVKNRLETPMELRLDSP-SAPDKPVVLPAIMPGDSFAVPLHLTSWRLQARPKGLGVFFCKAPIHWTNVVKTAEVSSSKRECHSMDTEKSRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEAALPTADTSQNIELGVSLENFPLCKELLIPPGTQNYMVR-MRLYDISRRQLNLTIRIACRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREFARGQGTANPSGYISTLPGSSVVFHWPRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPPPFRIDNFSKVPIVFTQHGVAEPRLRTEVKPMMSLHYAWDEPTLPPFITLTVKGAGSSEINCNMNDFQNNRQLYYENFIYIAATYTFSGLQEGKGRPVASHKAITCAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSAVPHNPNKPSATRSIEGSAILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWCFHEGKLTCGLHGLVVQAKGGLSGLFDGAEVVLG-PDSSVELLGSVPPEQQFANQKMRPGSGMLSVRVIPDGPTRALQITDFCQRKS---ERSSYEVEELPVTEQELQKLRNPDTHQELEVLVRLEGGIGVSLIN-KVPEELVFASLTGINIHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMVTAQKFTVQIEEKLLLKLLSFFGYDQAESEVEKYDENIHEKTAE-QGGTPTRYYFENLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKFAGTLSDGLGKTMDNRHQ--SEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRCCT-GPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVEN-----IDSYCVLISSKAVYFLKSGDYIDREAIFLEVKYDDLYHCLVSKDHGKVYVQVTKKAANSSSGVSIPGPSHQKPMVHVKSEVLAVKLSQEINYAKSLYYEQQLMLRLSEDQEQLELDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1ART1-1", "uniprot_id": "B1ART1_MOUSE", "id": "B1ART1-1", "name": "", "aln": "MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGLIGKVTLQIPFYRPHVDPWVISISGLHVIGGPEKIQDFNDEKEKLLERERKKALLQALEERWK------KGEPYWYSVT------ASVVTRIVENIELKIQDVHLRFEDGVTNPSRPFAFGICIKNVSMQ-------NAANEPVQKLMRKKRLDVAEFSIYWDVNCTLLG--DLPQAELQEAMARSMESRSHHYILEPVCASALLKRNCSKEPLRSRHSPRIECDIQLETIPLKLSQLQYRQIMAFLKELERKERQLKFRKWKPKVAVSKNCREWWYFALNANLYEIREQRKCWTWDFLLHRARDAVFYTDRYFNKLKGGVLSADDKEEMCRIEEEQSFEELKILRELVHDRFYKQEELAESLREPQFDSPGTSPGDPDGSGGS-GMLQYLQSWFPGWGGWYG--QQSPEGKVVEGLTAESHEHWTPEEILGTEEFFDPTADASCMNTYTKRDHVFAKLNVQLQRGTVTLLHKEQGTAHANESAFMQLEFSDVKLLAESLPRRNSSLLLVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTASEDRSDQYSAADPDNPVFEMLYERNPVHSHFERRLHVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYDKLKVQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFTFKNPVLVVVDLGRMLLTNTQEDSRRKSGDGSASEENQFSDDEYKTPLATPPSTPPPETSSSNGEKTPPFSGVEFSEEQLQAHLMSTQMYERYSLTFMDLQVMVGRVRDNWKRVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPETKPSD--TQIREKIFPQEGPRGSLQDSVMNLTQSIVMLEQHTREVLVESQLLLAEFKVNCMQLGVESSGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGPNVAFQTDVTT---LNDQSATS-VSLEKILTKEQESLIKLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDDVSPQPLMTDLERSIVEQGTIQSTYEQNTEVAVEIHRLNLLLLRTVGMADGERHGRKIATASIGGTKVNVSMGSSFDMNGSLGCLQLMDLTQENVKSQYVVSIG--------NSVGYENIVSDIGYFESVFVRMED-AALTEALSFTFAEKSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRSMLKSAATKVTTVLATKTAEYSEMVSLFETPKKTREPFVLEENEIYGFGLPSPRSDTVKLILNINIESPVVSIPRRPGSPELLVGHLGQIFIQNFVAGDDDSRSDRLQVEIKDIKLYSLNCTQLAGRDNAGPEVNRTFCPPSGLASVNSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERESELTFSLSPDELGTSSIMKIEGKFVNPVQVVLAKHVYEQVLQTMDNLVYSEDLNKFAASAPTSPCPNSP-LPQLSSCGEPCVEKKENGLFSHSSFSSTSQKSLSVKEAKAFTQIQANFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALRSLLMEDLLEKNPDSKYKSLMVSRGAPKPSSLAQKEYLSQSCPSVSSVEYPDMPRSLPSHMEEAPNVFQLYQRPISTCRKKPKEAQDKSYPQTPPPSPSVDEPNMLVGKSKFDDSLVHINIFLVDKKHPEFSSSYGRINRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMKVPPEGLLQNVKAESSASMESEHQEPVNSKLDLKVHSLSLVLSKATSELAKANVSKLMAHMEMIEGDLALQGSIGSLSLSDLTPHGDFYRERFTTSGEEALIFQTFKYGQ-PDPLLQREHDIRVSLQMASVQYVHTQRFQAEVVAFIQHFTQLQDILGRQRAAIEGQTVRDQAQRCSRILLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFAGFPGTFSLQDK-ESVPSASPAGTPKHSMRKMTTTEDPKGPQVQGLFMMPPAGVGLGSLKSDFVPSASIKQRGQQAVPPVSQSSSSPEDHVCLLDCIVVDLQDMDIFAAERHPREGSKASEHSSGDLIFPSYFVRQTGGSLLTEPCRLKLQVERNLDKEISHTVADISVHGSLSSVHCSLDLCKYKLIRGLLENNLGEPIEDFMRPYDLQ-------------DPRIHTVLSGEVYTCMCFLIDMVNVSLELKDPKGKEGTGSLARFDFKKCKLLYESFSNQTKSINLVSHSMMAFDTRYSGQKPSHGMTNVFNCIFQPSKSSSATQGSIQIELHFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDIKKQN-VTPARHRNASSESAVVPKTVKSGVVTKRSSLPVSNERHLEVKVNVTGTEFVVVEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSCRLGNEQDTALSIVDPVQIQVELVGNSSYQNSSGLMDAFNSEDFPPILEIQLQALDIRLSYNDVQLFLAIAKSIPEQASAAAPDSSALEVDS----ISCSLPGASRIGEDVREGSRHTLDPVLELQLARLQELGFSMDDCRKALLVCQGQLKKAASWLFKNAEPLKSLSLVSSSSRDNPGTMPAPRISGVEVKAESVCICFIDDCMDCDVPLAELTFSRLNFLQHIRTNPE------------GFAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQASSRLHPPRLKLEAKAKRRLDINITSVLIDQYISTKESWLADYCKEDKETESAKTEDWMGSSVDPPCFGQ-------------------------TEVKTPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGAFLDDAHNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFRYAAPDKNSSSSTIGSPSSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKVITVRSALIVKNRLETPMELRLDSP-SAPDKPVVLPAIMPGDSFAVPLHLTSWRLQARPKGMGVFFCKVPIHWTNVVKTAEVSSSKRECHSMDTEKSRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEAALPTADTSQNIELGVSLENFPLCKELLIPPGTQNYMVR-MRLYDVNRRQLNLTIRIACRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREFARGQGTANPNGYISTLPGSSVVFHWPRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPPPFRIDNFSKVPVVFTQHGVAEPRLRTEVKPMMSLDYAWDEPTLPPFITLTVKGAGSSEINCNMNDFQNNRQLYYENFIYIAATYTFSGLQEGKGRPVASHKAITCAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSAVPHNPNKPSATRSIEGSAILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWSFHEGKLTCGLHGLVVQAKGGLSGLFDGAEVVLG-PDSSMELLGPVPPEQQFANQKMRPGSGMLSIRVIPDGPTRALQITDFCQRKS---ERSSYEVEELPVTEQELQKLRNPDTHQELEVLVRLEGGVGVSLIN-KVPEELVFASLTGINIHYTQLAASHMLELSIQDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMVTAQRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDENIHEKTAE-QGGTPTRYYFENLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKFAGTLSDGLGKTMDNRHQ--SEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRCCT-GPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVEN-----IDSYCVLISSKAVYFLKSGDYVDREAIFLEVKYDDLYHCLVSKDHGKVYVQVTKKAANSSSGVSIPGPSHQKPMVHVKSEVLAVKLSQEINYAKSLYYEQQLMLRLSENQEQLELDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5THJ4-1", "uniprot_id": "VP13D_HUMAN", "id": "Q5THJ4-1", "name": "Intermembrane lipid transfer protein VPS13D", "aln": "MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGFIGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEKWKNDR-QQKGESYWYSVT------ASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKNVSMQ-------NAVNEPVQKLMRKKQLDVAEFSIYWDVDCTLLG--DLPQMELQEAMARSMESRSHHYVLEPVFASALLKRNCSKKPLRSRHSPRIDCDIQLETIPLKLSQLQYRQIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANLYEIREQRKRCTWDFMLHRARDAVSYTDKYFNKLKGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEELAESLREPQFDSPGACPGAPEPGGGS-GMLQYLQSWFPGWGGWYG--QQTPEGNVVEGLSAEQQEQWIPEEILGTEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHKEQGTPQMNESAFMQLEFSDVKLLAESLPRRNSSLLSVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTTSADRSDHYPAADPDGPVFEMLYERNPAHSHFERRLNVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFKFKNPVLVVVDLGRMLLTNTQDNSRRKSRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQLQAHLMSTKMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMKTSD--TQIKEKIFPQEEQRGSLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGPNVAHLTDGAT---LNDRSATS-VSLDKILTKEQESLIKLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTYEQNTEVAVEIHRLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSMGSTFDMNGSLGCLQLMDLTQDNVKNQYVVSIG--------NSVGYENIISDIGYFESVFVRMED-AALTEALSFTFVERSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRGMLKSAATKVTTVLATKTAEYSEMVSLFETPRKTREPFILEENEIYGFDLASSHLDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQNFVAGDDESRSDRLQVEIKDIKLYSLNCTQLAGREAVGSEGSRMFCPPSGSGSANSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERESELTFSLSPDDLGTSSIMKIEGKFVNPVQVVLAKHVYEQVLQTLDNLVYSEDLNKYPASATSSPCPDSP-LPPLSTCGESSVERKENGLFSHSSLSNTSQKSLSVKEVKSFTQIQATFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALHSLLMEDLLEKNPDSKYKNLMVSRGAPKPSSLAQKEYLSQSCPSVSNVEYPDMPRSLPSHMEEAPNVFQLYQRPTSASRKKQKEVQDKDYPLTPPPSPTVDEPKILVGKSKFDDSLVHINIFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMRLPPEGILHNVKLEPHASMESGLQDPVNTKLDLKVHSLSLVLNKTTSELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGEEALIFQTFKYGR-PDPLLRREHDIRVSLRMASVQYVHTQRFQAEVVAFIQHFTQLQDVLGRQRAAIEGQTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFAGFPGTFSLQDK-ESVPSASPTGIPKHSLRKTTSTEEPRGTHSQGQFTMPLAGMSLGSLKSEFVPSTSTKQQGPQPTLSVGQESSSPEDHVCLLDCVVVDLQDMDIFAAERHPREYSKAPEDSSGDLIFPSYFVRQTGGSLLTEPCRLKLQVERNLDKEISHTVPDISIHGNLSSVHCSLDLYKYKLIRGLLENNLGEPIEEFMRPYDLQ-------------DPRIHTVLSGEVYTCMCFLIDMVNVSLELKDPKRKEGAGSLARFDFKKCKLLYESFSNQTKSINLVSHSMMAFDTRYAGQKTSPGMTNVFSCIFQPAKNSSTTQGSIQIELHFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDIKKQNHVTPSRHRNSSSESAIVPKTVKSGVVTKRSSLPVSNERHLEVKVNVTGTEFVVIEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSCRLGNEHDTALSIVDPVQIQMELVGNSSYQNSSGLMDAFNSEDFPPVLEIQLQALDIRLSYNDVQLFLAIAKSIPEQANAAVPDSVALESDS----VGTYLPGASRVGEEIREGTRHTLDPVLELQLARLQELGFSMDDCRKALLACQGQLKKAASWLFKNAEPLKSLSLASTS-RDSPGAVAAPLISGVEIKAESVCICFIDDCMDCDVPLAELTFSRLNFLQRVRTSPE------------GYAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKPRLDINITSVLIDQYVSTKESWMADYCKDDKDIESAKSEDWMGSSVDPPCFGQSLPLVYLRTRSTASLTNLEHQIYARAEVKTPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDTHNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFRYAAPDKNSSSSTIGSPSSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKVITVRSALIVRNRLETPMELRLDSP-SAPDKPVVLPAIMPGDSFAVPLHLTSWRLQARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECHSMDTEKSRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEAALHTADTSQNIELGVSLENFPLCKELLIPPGTQNYMVR-MRLYDVNRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREFARGQGTANPEGYISTLPGSSVVFHWPRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPPPFRIDNFSKVPVVFTQHGVAEPRLRTEVKPMTSLDYAWDEPTLPPFITLTVKGAGSSEINCNMNDFQDNRQLYYENFIYIAATYTFSGLQEGTGRPVASNKAITCAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSSVPHNPNKPSAARSTEGSAILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWSFREGKLTCGLHGLVVQAKGGLSGLFDGAEVVLG-PDTSMELLGPVPPEQQFINQKMRPGSGMLSIRVIPDGPTRALQITDFCHRKS---SRS-YEVDELPVTEQELQKLKNPDTEQELEVLVRLEGGIGLSLIN-KVPEELVFASLTGINVHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITAQRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDENLHEKTAE-QGGTPIRYYFENLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKFAGTLSDGLGKTMDNRHQ--SEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRCCT-GPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVEN-----IDSYCVLISSKAVYFLKSGDYVDREAIFLEVKYDDLYHCLVSKDHGKVYVQVTKKAVSTSSGVSIPGPSHQKPMVHVKSEVLAVKLSQEINYAKSLYYEQQLMLRLSENREQLELDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0ZAE9-1", "uniprot_id": "A0A8V0ZAE9_CHICK", "id": "A0A8V0ZAE9-1", "name": "", "aln": "MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGFIGKITLQIPFYRPHVDPWVISVSKLHLIGAPEKKEDFDEEREKLQERERKKALLVALEEKWKKER-QQKGESYWYSVT------ASVVTRIVENIELKIQDVHLRFEDDITNPLQPFAFGICIKNVSMQ-------NAVFEPVEKLMRKKQLNVADFSIYWDTDCTLLG--DLPPAQLQEAMDKSMESHDHNYIMEPVCTSALLKRNCSKEPLRSRQTPRLECDIVLETIPLKLSQMQYQQIMAFLKELARKERQLKFRKWRPKVTVTENCREWWIFALNANLSEIREQRQRSTWEFVLHRAQDAVSYTDLYYCKLKGEPLSAAEQEEMHRIEDEQTYEELKILCELVHDKFH---DLAESIKEPLPDSPGASPSAESAHGSSTGMLQYLQSWFPGWGGWYGYTQQPYEGEPFEGLLPDPQEQWNPEDILGADDFFDPAADASSMNTFTKRDHIFAKLNLQLQGGSFTLLHKEKKVARAEESAFMQLEFSGVKILAESLPRRNSSLLKVQLGGLFLRDLATEGTIFPVLVFPNPQKEVGCVS-SFGLQNLSSEMTN--QSTDPDAPVFEMLYERNPIHSNFERRLEVSTRPLNIIYNPQAIKKVADFFYKGRVHTSGFGYQSELEAKVAEAARRQYNKLKMQTKAEIRQTIDRLLVGDFIENSKSWTVCLDISAPQVIFPDDFKFVDPVLVVIDLGRILLTNSQEESKR-NADAFSPEFNELSDEEYKTPLATPPNTPPPETSTNSGIKLSGFTGVEISEEQLQAHLMSKKMYERYTLSFLDLQIMVGRVKDNWKHVQDSDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGSLPDLKIHINEDKILALKNCCTQLSASETKSSDGLNLGKDKIFSEVDQLGTLHDSVMNLTQSVVMLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGTDFDLLMASHKNLSFDVPTGSLRDSRAQSPVYGPCDAHPIDASS---LAERCAVASNTSSGNNGKDQESLIKLEYQFVSAECPSMNLDSSLQVISVQVNNLDIILNPETIVELIGFLQKSFPKEKEDSSPQPLMDDTERVWREQETFQSTYVQNTEVAVDIHWLNILLLRTVGMTNGEKYGRKIATASIGGTKVNVSMCSKFDVNGSLGCLHLMDLTQDGVKNQYVVSIG--------NTGRYENLIGDVDYFESLFFRLDDGSSLPDALSFTLTEKSKEECSLNLKMASLHYNHSAKFLKELTLSMDELEENFRSMLKSAASKVTTVLATKTAEYSEMVSLFDTTPRSRDAANLEDNDGYAFGSPPLKSDTIKLILNINIESPIVSIPRKPGSPELLVGHLGQMSIQNFVPGEDESTSDRLQVEIKDIKMYSLNTSQFMSKKESASEVSQGLHS-SGPASINSQEESQFTRHDFFESLHKGHAFHILNNTTIQFKLEKIPLGRDLDVTFPLSNEDFGISNIMKIEGKFVNPLQVVLAKHVYEQVLQTLDNLIYNEDLNKFPAAAASSTCHSSPSASALSTGTEFSSERKENGLFSHSSFNSIPSKSLTIRETKSFTQIQANFHISELQVQLSGDLTLGAQGLVSLKFQDFDVEFTKDHPQTLSIQIALRSLLMEDLLEKNPDSVYKNLMVSRGAPKPSSLAHKEYLSQSCPSVSNVEYPDMPRSLPSHMEEASNVFQLYQRPVCASRKKQKEDADSEYPLTPPPSPTADRSKLPCGKSHFDDSLVHINIFLVDRKHPEFSSRYNKINRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMKLQPEDTQQTSKSEVNTLSASAAQEPVNTKLDLKVHSLSLVLNKTMSELAKASVSKLAAHLEIIDGDLALQGSIGGLSLSDLTAHGEFYRERFTTSGEEALIFQVYKYGR-PDPLLQRECDIRVTLRMASVQYVHTQRFQAEVVSFIQHFTQLQDVLGRQRAAIEGQTVRDKAQRASRVLLDIEAGAPVLLIPESSKSNSLIVANLGKLKVKNRFLFAGMPGTFSLKNKQDSAQFSSPLGTPKHSMKKTTSADESK-VVMEGLFMKKPSGGNVSRLKSELN--SLSKPQGQQSKLPVVPNPESPEDHICLLDCIVVDLQDMDIFAAERYPREYSKAVEDTSTDLSFPSYCVRQTGGSLLKEPFRLKLQVERNLDKELSHAVADILIHGNLSSVHCSLDLTKYKLIRGLLENNLGEPIEEFMRPYDLQ-------------DPRIHTVLSGEVYTSMSFLVDMVNVSLELMDPKGKDECSSLARFDFKKSKLLFESSSNRTKSVNLVSHSMMAFDTRYAGQKSTAGMPNVFNCIFQSSKNTSS-PGAIQIELHYRSTKDSSSFTVVLNNLRVFLIFDWLLLVHDFLYTPGDTKKRENVLSSRQRTYSSETSVVPKAVKSGVVTKRSSLHVSTEKQLEVKVNVTGTEFVVVEDMSCFDTNAIILKGTTVLTYKPKLLDRPFSGSLFGIEVFSCRLGNEQETALSIIDPVQIQVELVGNASYPSGSGLLDAFNSEDFPPILEIQLQALDIRLSYNDVQLFLAIAKSIPQQTSAAMPGSGASVAESSANPSSSLVAEPSCLTSENRETPKRVLDPVLEVQLARLQDLGFSMEDCRKALLCCQGDLKKAASWLFKNAEPLKSLSLSSSG-RDSQGTVPFQFISGVEIKADSICICFIDDCMDCDVPLAELTFSRLNFLQHLRANPE------------GCARFTLSGDYYNRELSGWEPFIEPWPCSVSWQQHASSRLHPSRLKLEVKAKHRLDVNITSVFLEQYARTKQSWMEDYCKQDKEVNAVSSEEWTGSSEDSPCFGQSLPLVYLRTRSTASLTNLEHQIYARAEMKTPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEENGTLLDDAHNVSEWKEVITGEEVPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEEVSPVSVDKVGTFFRYAAPDKNSSSSTLGSPISRTNIIHPQVYFSSLPPVRVVFEVTMEGSARKVITVRSALIVKNKLETPMELRLDSP-SAPDKPVVLPAVMPGDAFAIPLHLTSWRLQARPKGLGVFFCKAPIHWTDVQKTAEVCSSKRECHSMDSENSRFFRFCVAIKKENYPDYMPSSIFSDSAKQIFRQPGHTIYLLPTVVVCNLLPCELEFYVKGTPISGTLKPGKEVALHTADTSQNIELGVKLENFAICKELLIPPGTQNYMVR-MRLYDVNKRQLNLTIRIVCRAEGSLKILISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNFCTMRVGKGIHPEGMPGWCQGFSLDGGSGVRALKVIQHGNRPGLIYNIGINVKKGRGRYIDTCMVTFAPRYLLDNKSSYKLAFVQREFARGQETSNPDGYISTLPGSSVVFHWPRNDYDQLLCVRLMDFPNCIWSGGFEVNKNNSFHINMRDTLGKCYFLRVEITLQGATYHVAFSDTDQLPPPFRIDNFSKVPIVFNQHGVVEPRLYTEVKPMTSLDYAWDEPILPSFVLVTVKGAGSSEIVCSMNDFQDSKQLYYENFIYIAATYTFSGLQETSVRPVASNRDAAYAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLCHEGSSVPHNPHKPSP-RSVESCMILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWSFRDGKLTCGIHGLVVQAKGGILGLHDGAEVVLG-PDTSLELLGSVPPEQQFINQKMRPGSGVLAVRVIPDGPTRVLQITDFNQRRN---DRLSGGGDELPITEQDLRKLKNPNMEQELEVLVKLEGGIGLSLVN-KVPEELIFASLTRINVHYTHMSASQVLELSVQDVQVDNQLIGTTRPFMLFLTPRMSENEPVETAPAVQVNAMKFPSKNALTDIYKHLMITARKFTVQIEEKLLLKLLSFFGYAQSESEVERYDENLHEKVVE-KGGGQKRYYFENLKISVPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETQEFIINDVLKHFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKFAGTLSDGLGKTMDNRHQ--TEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAERVRKPRCCR-GPQGLLPRYSAREAEGQEQLFKLTDNIQDEFFIAVEN-----IEKYCVLISSKAVYFLKSGDYPDREAIFLEVKYDDLYHCLVSKDHGKVYVQLTKKAVNTSSGVAMPGPSQQKPMVNVKSEVLAVKLCQEINYAKSLYYEQQLMLRLSENQEQLELDS", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9VU08-1", "uniprot_id": "VP13D_DROME", "id": "Q9VU08-1", "name": "Intermembrane lipid transfer protein Vps13D", "aln": "MLRDLITWVLNTYLGKYLENLNSAQLSVALLSGEVELENIPIRKDALRSFNLPVEVTAGSIRKIKLQIPVRQFRTSPWCISIEGLFCIICPKNLDNWDYEKEKLQDLEYKLAVLDTAEAGWRSEKGKQMESYYFSSYNNWLKYGTNMATNIIDNIELKISDVHFRFEDIVDTGKSKICTGIKIGSLTAQSCDCDWTNGSYKMNNNEMNYKLVELKELSVYWDLLHEDIKCQSYSNQEILEKMHSTCELRSHNFIIKPICATARWKRDKCQQVIRTKDKPRVSCELLVPEVVIDISKVQRLQMLDKLSEIRQVKEVRQYRLKRPTCTVESNPIAWWKYATICHGFDFKKNEE--KWLMLKENLRYMLLYKSIILNPNEN--LSAADKEFKAYIESDRKISDLTIMRRICFEKVFTKGFAFESQNEQGKN--------------------MLFHWFPNWMGWYANSPSTPNNEQDESLKH------------LEDDILVALENSLQNSSDLKSDAVFGHFSIKLLKGLVILQTEDKLNDGRNKS--MEMQFNNFSAYLQLSPQLTSYTVGISLQEVYLIDKTSSDTMHNYLIKPQTG-------------NTATPNQLVKNAALQEDILFQLQYEN---CNHLRFQLNIKSKGLDLIYNEDAIQWLLDFLAD-------------------SNSFKYSPRNRVAKKTDFMKNWNEMFSGNEVN-RKIWMFEIEIFAPRIIFLENYKVSNSLMVLLDFGKLEMRKMEVKRVIPVIESAVTENTSDDDETYLTPCSTPPASEKSGSESPTLLENP-KTESFLNKNVQLEYVLHNKIYDKYLINFTNLQVLVCKYEERWQACLKTSSN-FHLIDKFNINLTLEQRNIFTVDPEYPSFMLFGTCPTILIHGNEELINNCCNIMKPIIKASKEMEN----------------------IYRGGNTIYASERIKNLAEDDRSRVVIEFVMDQLVIEMQSTERSIAELQIIGARAGLTKEPHETNISMSVHGLLLVDAIQSFGPDFELLVASHRHVGMDSLSGSLKHSAIVSPTSPGSPNFFDRATSPHMITKAVQNIKMGDRSTEFCDDEDSTALISVDIKIVPPNESNSMQLHTTSITFNSLDIIANQDTIIEILNFAKRTLLAQNIFPSESPESPKEATEAPVDVVDQVDHKSHNEIFFDFFRLNILLLYTIKR-DKFNVGRKVGTVTLTEAKINASFQSDLSIIGSLGGIQVIDITSEAFCHPRILSVGRDQILRASDTNKQTVLSQLSNEIYSNNYNEETKSDESDAISFQSHWSDKTTCTFQMRMASASYTHCPRFLRDVNACITYFKRSLREFATSIGNKAT---------------------DMAKEFVQQVRAVEQIGPVYPQRNRQDNWLDIIISSPIIILPISNTSTNVLIANLGKISCSNAVKCDSDEFNESYTIEIKNTYVYSLNIDEGEYSFNVHPAKN-------------------------------KDAIPILHDTAITLQLYAG---------YSDDNDEDKQLNRFSIKGSMVEALKVSLNRKQYELLLESIR---YATNFSNEVLNESDELDQNGD------------------------------IEPTANIDAESIISTTIQFSVPVFQINLQNEYHN---DLINLTFKNFNVKHISKG-FDKDVEVVLKSVLMEDLKS-DLTSPFRNMVTS--VDLEQKIKKNEMTSSSCP-----DLPSYCNSLKNRSSSVPSCFYNHMQVKVFGGDQKYTSSNKNELGKKKES----------------------QTLVIYKSHTGRSAQNGKLEQTSSIQFNCLNLAICVERWYTIFDFFGLVSVDN------------VNEKYPEEMKLVEKHIDKVCSKLKVSIRSFNFTLIRNESLLSRVNVSNAVFMILQDPYSKIVEGCLGSVSVNDLTKYGNIYKQKFLTSGTEALNFVYKKKLVDLEALNTLDTDSTLRINMSAVHYIHTKRFSTELHVFVKDLLQLQTPVIRKLKKHG----SEQNMRPSKMKLVIQADSPVIVLPSSYNRNEVIIAYLGQFSLKNSFHFASDN--------------------------------------------------------------------------NIISKMSATPSKDEILDVMRIDLVNINLFSGERSSMKAKADQEKDR--IIIADMNFLRLGQPFFNESCFLHLQLERNLSADAHRVCPDISVQGTFSKLSGIINIQQYKLIRSFLNNNIGEQTDDIYMNYHNNSCTSIERLSTINLMPKNEVSKIVSILISIRILLEDVSLLLALNTSQS-AAIEPLACIHFLKSTLEIDLFSDGSQDIDLISSNILIVDERNESDKSNE---NVFKNILEPSKKEVRIENSVQVEVHCRKKATFSKYTIMLNNMRVFALLSFLDQLKSYLQEDSPAPVVNNAANQIAQKPQIDTSIS----------------------TEYVVNITDSEIIFAEECSRLDSNAIILKSTTVICYKPNSNIVPLSLDINHLEIFSCTLDAEEESALSIIDPFTLIIELRSNCLN-------------------ILIQKHLNIRLSYVDVKLFSRMARLLPTQTSRPKNVISKADSDL--------------------------------EKAAPLVAMGFEISDCLYAMQINNWRINDAAIWLSQQKQ--------------NTYRNPALEMKTAVVDASLISVFIIDDCMDADVPLLEVSLSKFLLNFTFQTQDPNPKETNIRHYSLGNIDTEVSVNYYNRRLSGWEPVAETWESNLNWKYTKGHLDNKKRFEIGISSKQMLKLNVTSTFIELFHMVLKNWTNDFNDNG--------------------------------------------------AKNFRQRSPFIPFALQNLSGTPLLFKPIYAP--------------LGDLTRSDLQQVELIKNWYSVQPNETKTFDFSQKSKLRHVHSHQLNLHQIFVQIHGWTLIGPISVDKVGMFFRTTKLDS-----------------------QFLTKSRIVFDISLIGSAQKLIKVKSSLGVINKLDRNVFLKMTLKGTHSDGLSSISVIKPNDELSVPLKFIDASLYVAHN----------TSESDAYEDTGFSNEEILWKACGKDDTRQLLAGYDTNKSILYTFVNISREIYHCKEQN-LPGHKITLLPPLKINNMLCCDLMFKIHEHATG-RINSSESVNIYNVNICQPLNLSITLDNFQLSGQLKIPVSHRGVIEPKLKLIDIQKRELHVRVSIQSVPGKGMELYISAPVWIINKTGLPLIYKQEGTSHTAAGQFEEHETARQVAPLMFSFSDQEGSPALVLRLGKAYGSN--NMWCKSFSTHKDLADRDLRAENTKG----SYAIGISVRRGRGLYACTTFVTLSPRFHLHNRSGYKLEFMQLCDIVNYDRPDPRKIISAPVDCNFAFHWPNWDQEQIICVRIPEIECCCWSKGIPIKDVQSLYINVRNEWGEMFFLRLEIISKDATFILLFTDARTLPPPIRIDNCSEVVINFSQL-RSKPVWITPVRPQSSLSYVMDDPLGQQILLMEAPGGNMIEFPINNKNN-IKKTLTYTNFIYIAFQGTFE---------RSNEEENTHRQLVLGVR--GKKVVIVEKNSGDRSQLWLMNSNGQLEHEGSTPPIQTNDANAVRLVLDLEKAPNP-------MEFTNLVVRTPNKQRVTTQTWRFENGRLMCHAN-MCVQSRFGESGLKPNYEAVVGRTENRASSSKQIPIGQHIVAQKLRPGSGQLELSTKMDGPISTIEICDIKIKQNSVFLTPDLLWMHASLNNRQITDKGKVSFVHEYLINVELVKGIGISIIARKPCEEIMFISLDHINCDIVQSALENSLDLNIAYIQIDNQLLDAVSPIALHTQTS---NDLEETQNAVVLKLKMLPSPNKNAIIFKYLTLDLKPSTASLEEKLILKVASFLGYGKINRQNLSVQYQFENTDDKPFLQDMKRYYFENLSIGATQVRLSAFTSSKLPVELHETKKALGLTLIKFEDALIELDRYSDKLHFETMDVYRKELKKHYINQVKWHAAAILGSVDFLGNPLGFANDLSEGVSGLIFEGSVKSLVKNVTHGISNSTAKLTETLSDSLGKVVLDDHDNETRQRILELQSNTSGGHLAAGLKGLGFGLLGGVTSIVRHTYDGATSDG-VPGFLSGLGKGLVGTVTKPIIGVLDLASETASAVRETSRDS-HRNAPERKRLPRCVTGAPGGLLPLYSNRQSKGQQYLYLINQKNFSEKIISYEPNLWSDKEARLRLLVSTEYVRIFSLSDANPTIMFECHVSEILSCHPVVTNAGTTPTTSSRASASHYIEISTNLPKITRPRIRCRSEECAEAASRCINYAKSVFDEREHAVL------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**..*::**********::***: *******.* *****:*::****:.::**.**.** * *:.****. : :..** **:. *. * *:: :::: *:*** : * * .:* : * *: . *: * . :.:.*.*::******.***:**** : . :. ** * .:: * *. : :: *. * ::: ::*:*** : . . :: * * : * :.*:::::*: ::* **: .:: :*::..**:.*:: : : :.:*::* *:: *.*: : :. ::* :*. :: .* ** :* .: :::::.: .* :: .. : : *.. :. **: ::* **.::. .:*.*: .: .::.. ** .* : * ***.* ***. .. :.: *.* :::: . :: .: * * :*.::.::* * . * ::: ::* *:::*.... : *: .* : : * ::* * ::..*:. *: *:. . : :: : :*:: **. .::. :*.:.:: *::*** :**: : **: . . : : : :: .*::: :. :.:: *: :: * * . ::* **::** :::.. :.::*::*:*:: : : : . : .* .. .*: * ** :*** : . :.: . : . : :.:: ::: .::*::* :.* :**::* : .:.*: . . . *:::***::* **:* *:* **:**. :* *. * : ** **: * * : .. : .: : . ::: *: .. . : . :: ** :: : : ::*. * *: *:::*:.* :.*.*:::::*::********::*::*.**:**:***:::.:* :***:.* **. . :: : . ::*. * :. *. . . *:. *: .*.**** * :**:*::.* :::: :: * .* . : . * : .:.*: .::. **:*** *: : . ***:.*.:: :*:*.*: * :.: **** ::::*:*.: . ::*:* :: : . : * . : : .:*:** .* * ::::*** *.*..:**:::. .: ::..:* : .* ..*.* . : . :. : : . *:* *.**:: :* *.::*:.:**:: .* * :.:. .: :***: :**** : . . .*: **::*:* ::* :. . :: . :.*:*.:*:.::* * :: ** :*::: * ::.: . . .. :. : : ::: . * :. :*::*..: .*:.*.*::*:*:. .. .:::.*:*:***** . : * ::.::.* . ..: ::* *.*** : * .** .: ..... * : : .: :.. . * : ::: :.*. *: .::::: .::****:: * :: * .*:****: *. : . * . : * :**.:.::*:.:.* : * *::..**: : . ::*.:*.:*:.*** :*::*:::* *** *** * * :.* : * : :.*::*:*:**:**.:*: *::.: *** : *: :: * *:: * *:*.:**:::*.* . *.:*:* **::.:** * **. : . .:. .: :** : :** ::::*:.** . : . * : :.. . : * .::.*. *:**:****. : :. .** ::*.:*.: ::: :*****.:*:**:** ::: *. : *: .. .: .: :*:: *.: * * .: .** :.* *..* : *: ::.::*:* .:: .* * .:*.. ***. *::.:*. .::*:*:* *.. * :*::***:*** ::.:* ::.:* . : . :. . :::: * **:*.:*::. *: * :*:******.***: ***. *:* .: :*:*** *. *.::****:**. : :** .*. : : *:***** **:** :*: :* *:. . : : * * :**.:.** *: : ::.** ** :: : . . :. . :.*. :.: :******.**** *:::*:: : .::. * :* :**** ******. *.* ..:.*: . : *::: .:* *.:*:**.::: : . :.* *: .:. *. ::*.**:****:* :* .* * .: :. : : . : *::.. :.:* .* ..* .*:*. :.**** *:*:*.:**: *:::** :.*:****** *** : *. . *. *:** ::: ***:*:*.*:*:* * *:*: : *:: : .* :..: *.* :::**:: . * . : ::. : : ....: :: ..:.:* : :*. :: . .*: ***.* ***.: : *:* *:* * :: . . ::..:.. : ..: .* ::*.:.*:** :. :* ** . :. : ::* *:.:*:*:: : * . . .::: **** *:*********::*:.:. ********* **.::**:*.::*:* . .:*:*:. .: **:.** . . . * *:. : . * ***.*::*** * * :* ::**: *.*:*.:** * * . .:* **: .....****. * :*::***: :. * ** *: ::. :*::**:*: *: :***:** :.**: : *:*: ****:**** *:* : *.* :* * *:* ** *. *:* :: : . *.. *: . :: .: * * ****** **. :... : :***.* ::*:: :*:.*.***** *...* * ****: * :.:.... * . . .: *::*.*:::* ***** *.:*:* * : : **:: * ** . *.*:* .:. . :* *:: **:***** * : . *** .::* *: ::. . .:.:::: . : . :* : *.* *:*:*:: * **::* ** ** . .: : .: *:*.: :*:****:.:. *: *. . *: ** ** :: :** . : *:*:* : : *..:****:**: **:** : : : : ::.:. : *******.*. .*::**.***.***::*: *.:**:.**:****:*:** :: :** :. ::: **: ::: :** ***********:*: **:****:*** *.* .*::*****:***:**:: ****.***.: : *: :.:. :. :: *** **.**::**..*::**:**:: * :*..::* *.**:**************: *.**:*****.***:*: * *. .:* * *** .* **** ** :::**: *: :.:: .* :*: * : *: *. : * . : :* : * * .: *.. . :: :.. :: *. :* :. :** * .: ******:: *:: : ", "identical_positions": 1085, "similar_positions": 1467, "identity": "24.26%" }, { "cls_id": "homologset.oma.816470", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A1D9-1", "uniprot_id": "A0A8I6A1D9_RAT", "id": "A0A8I6A1D9-1", "name": "Vesicle transport protein USE1", "aln": "---------------MPALPPLSKMAQAEGACHR--PLATSRLELNLVRLLCRCESMAAEKREPDEWRLEKYVGALEDMLQALKVQASKPASEVISEYSRKVDFLKGMLQAEKLTSSSEKALANQFLAPGRVPTTAKERVPATKTVHLQSRARYTSEMRSELLGTESSGELEADMRKRV-VKGPRPADEKQSASELDLVLQRHQGLQEKLAEEMLGLARSLKTNTLAAQSVIKKDNQTLSHSLKMADQNLEKLKLESERLEQHAQKSVNWLLWAMLIVVCFVFISMILFIRIMPRLK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ56-1", "uniprot_id": "USE1_MOUSE", "id": "Q9CQ56-1", "name": "Vesicle transport protein USE1", "aln": "------------------------MAQAEGAYHR--PLATSRLELNLVRLLCRCESMAAEKREPDEWRLEKYVGALEDMLQALKVQASKPASEVISEYSRKVDFLKGMLQAEKLTSSSEKALANQFLAPGRVPTTAKERVPATKTVHLQSRARYTSEMRSELLGMEPSGECEVDMRKRA-AKGSRPADERQSASELDLVLQRHQGLQEKLAEEMLGLARSLKTNTLAAQSVIKKDNQTLSHSLKMADQNLEKLKLESERLEQHAQKSVNWLLWAMLIVVCFVFISMILFIRIMPRLK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8C2LA05-1", "uniprot_id": "A0A8C2LA05_CRIGR", "id": "A0A8C2LA05-1", "name": "Vesicle transport protein USE1", "aln": "------------------------MAQAEGAGHR--PLATSRLELNLVRLLCRCESMAAEKREPNEWRLEKYVGALEDMLQALKVQASKPASEVISEYSRKVDFLKGMLQAEKLTSSSEKALANQFLAPGRVPTTARERVPATKTVHLQSRARYTSEMRSELLGMDSSGEREMDMRQRI-ANGSRPVDEKHSVSELDLVLQRHQGLQEKLAEEMLGLARSLKTNTLAAQSVIKKDNQTLSHSLKMADQNLEKLKMESERLEQHTRKSVDWLLWAMLIVVCFVFISMILFIRVMPRLK-", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q9NZ43-1", "uniprot_id": "USE1_HUMAN", "id": "Q9NZ43-1", "name": "Vesicle transport protein USE1", "aln": "-------------------------------------MAASRLELNLVRLLSRCEAMAAEKRDPDEWRLEKYVGALEDMLQALKVHASKPASEVINEYSWKVDFLKGMLQAEKLTSSSEKALANQFLAPGRVPTTARERVPATKTVHLQSRARYTSEMRSELLGTDS-AEPEMDVRKRTGVAGSQPVSEKQLAAELDLVLQRHQNLQEKLAEEMLGLARSLKTNTLAAQSVIKKDNQTLSHSLKMADQNLEKLKTESERLEQHTQKSVNWLLWAMLIIVCFIFISMILFIRIMPKLK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6QDZ3-1", "uniprot_id": "F6QDZ3_BOVIN", "id": "F6QDZ3-1", "name": "Vesicle transport protein USE1", "aln": "MGQQTNRALPTGKRPRRALPPSLKMAPAEGAEYHWVVMAASRLELNLVRLLCRCEAMAAEKRDPDEWRLEKYVGALEDMLQALKAQASKPASEVLNEYSRKVDFLKGMLQAEKLTSSSEKALANQFLAPGRVPTTARERVPATKTVHLQSRARYTSEMRSELLGTDSSEEPELDVRKRTGASGPTPRDEKQSAAELDLVLQRHQNLQEKLAEEMLGLARSLKTNTLAAQSVIKKDNQTLSHSLKMADQNLEKLKTESERLEQHTQKSVNWLLWAMLIVVCFIFISMILFIRIMPKLK-", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A8V1AAU3-1", "uniprot_id": "A0A8V1AAU3_CHICK", "id": "A0A8V1AAU3-1", "name": "Vesicle transport protein USE1", "aln": "-------------------------------------MAATRLELNLMRLLSRCEALAAERRDPEEWRLEKYVAALEDMLRELKKQSSKPPPELLNEYTRKVDFLKGLLEAEKLSSSTEKALANQFLAPGRTPTTVKERTPATKTVHLQTKARCTGKMRSELLGTDPLAISDSEEPNIRKRKGLAP-DEKQSAVELDAVLQHHQDMQEKLAEEMLSLARSLKNNTLAAQNVIKQDNQTLSHSLRMADQNFEKLKDESDRLEQHAKKSVNWLLWIMLIVVCFIFISMILFIRIFPKLK-", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9VSU7-1", "uniprot_id": "USE1_DROME", "id": "Q9VSU7-1", "name": "Vesicle transport protein USE1", "aln": "--------------------------------------MATKLNVNIRTLLANCEELAKS--EQNFWRLQKFIKSLDTMLAELEAMGDPQSVKRIPGYLER-------LQALKISTGYADVPGSTTKTPSQSSAVSETGENALKEIRQLQNSKYHNELRKELLQDSDALRRRRGADESSSSSGSANVQETS-GENMNQAAKYYTNAQEKITEHMLSLTRNLKEQTETANRIIRRDTEVVSRSAGMADRNINSLGKEAEKLEQHSKKAYKCWLWLMIAFVIATFIGMVLFMKIMKKKKS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::*::*: **..** :* . : : ***:*:: :*: ** *: .. . : : * : *:* *:::. .. .. :*.: .:. . * * :: .:: .::*.*** . : * .* ::: . : : . ***::*.**.*:*.** :* :*: :*::*.:.:*:* ***:*::.* *:::****::*: . ** *: .* **.*:**:::: : * ", "identical_positions": 65, "similar_positions": 96, "identity": "21.81%" }, { "cls_id": "homologset.oma.816484", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P19258-1", "uniprot_id": "MPV17_MOUSE", "id": "P19258-1", "name": "Mitochondrial inner membrane protein Mpv17", "aln": "MA-LWRAYQRALAAHPWKVQVLTAGSLMGVGDMISQQLVE----RRGLQQHQA------------------------GRTLTMVSLGCGFVGPVVGGWYKVLDHLIPG------TTKVHALKKMLLDQGGFAPCFLGCFLPLVGILNGMSAQDNWAKLKRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAIVWNSYLSWKAHQF------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5BK62-1", "uniprot_id": "MPV17_RAT", "id": "Q5BK62-1", "name": "Mitochondrial inner membrane protein Mpv17", "aln": "MA-LWRAYQRALAAHPWKVQVLTAGSLMGLGDIISQQLVE----RRGLQQHQT------------------------GRTLTMASLGCGFVGPVVGGWYRVLDHLIPG------TTKVNALKKMLLDQGGFAPCFLGCFLPLVGVLNGMSAQDNWAKLKRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVVWNSYLSWKAHQL------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A287AZQ7-1", "uniprot_id": "A0A287AZQ7_PIG", "id": "A0A287AZQ7-1", "name": "Mitochondrial inner membrane protein Mpv17", "aln": "MA-LWRAYQRALTAHPWKVQVLTAGSLMGLGDVISQQLVE----RRGLQEHQT------------------------GRTLTMVSLGCGFVGPVVGGWYKVLDRLIPG------TTKVDALKKMLLDQGGFAPCFLGCFLPLVGTLNGLSAQDNWAKLRRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIWNSYLSWKAHRL------------------------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q2KIN6-1", "uniprot_id": "MPV17_BOVIN", "id": "Q2KIN6-1", "name": "Mitochondrial inner membrane protein Mpv17", "aln": "MA-LWRAYQRALTAHPWKVQVLTAGSLMGLGDVISQQLVE----RRGLQAHQA------------------------GRTLTMASLGCGFVGPVVGGWYRVLDRLIPG------TTKVDALKKMLLDQGGFAPCFLGCFLPLVGTLNGLSAQDNWAKLQRDFPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIWNSYLSWKAHRL------------------------", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "P39210-1", "uniprot_id": "MPV17_HUMAN", "id": "P39210-1", "name": "Mitochondrial inner membrane protein Mpv17", "aln": "MA-LWRAYQRALAAHPWKVQVLTAGSLMGLGDIISQQLVE----RRGLQEHQR------------------------GRTLTMVSLGCGFVGPVVGGWYKVLDRFIPG------TTKVDALKKMLLDQGGFAPCFLGCFLPLVGALNGLSAQDNWAKLQRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIWNSYLSWKAHRL------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5TZ51-1", "uniprot_id": "MPV17_DANRE", "id": "Q5TZ51-1", "name": "Mitochondrial inner membrane protein Mpv17", "aln": "MAGLWRSYQALMAKHPWKVQIITAGSLVGVGDVISQQLIE----RRGLANHNA------------------------RRTAKMMSIGFFFVGPVVGGWYKVLDKLVTG------GTKSAALKKMLVDQVGFAPCFLGAFLGITGTLNGLTVEENVAKLQRDYTDALISNYYLWPPVQIANFYFIPLHHRLAVVQIVAVVWNSYLSWKANKM------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9LV46-1", "uniprot_id": "Q9LV46_ARATH", "id": "Q9LV46-1", "name": "", "aln": "MLKLWRWYQRCLTVHPVKTQVISSGFLWGFGDVTAQYITHSTAKRRLLRLTETNKDADADAEIKVKWKQDAEFKVNWKRVAITSMFGFGFVGPVGHFWYEGLDKFIKLKLRYVPKSTRFVAAKVAMDGLIFGPVDLLVFFTYMGFATGKNTAEVKEGLKRDFLPALALEGGAWPLLQIANFRYVPVQYQLLYVNIFCLVDSAFLSWVEQQKDAAWKQWFTSSFQPLKERGGQGGV", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *** ** :: ** *.*::::* * *.**: :* : . ** * : *. :* ***** **. **::: :. . *: :* *.* * *: * .* .. : *:**: ** : ** :*:*** :*::::* *: ..:: .::*** :: ", "identical_positions": 55, "similar_positions": 50, "identity": "23.4%" }, { "cls_id": "homologset.oma.816485", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NR77-1", "uniprot_id": "PXMP2_HUMAN", "id": "Q9NR77-1", "name": "Peroxisomal membrane protein 2", "aln": "-----------------------------------------------------MAPAASRLRAEAGLGALPRRALAQYLLFLRLYPVLTKAATSGILSALGNFLAQMIEKKRKKE-NSRSLDVGGPLRYAVYGFFFTGPLSHFFYFFMEHWIP-PEVPLAGLRRLLLDRLVFAPAFLMLFFLIMNFLEGKDASAFAAKMRGGFWPALRMNWRVWTPLQFININYVPLKFRVLFANLAALFWYAYLASLGK-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A287AV17-1", "uniprot_id": "A0A287AV17_PIG", "id": "A0A287AV17-1", "name": "", "aln": "-----------------------------------------------------MAPAASKLRTEAGLGALPRRALAQYLRLLRLYPVLTKAATSGILSALGNFLAQMIEKKQKKESCSQKLDVNGPLRYAIYGFFFTGPLSHFFYLFLEHWIP-PEAPWASVQRLLLDRLLFAPAFLLLFFLIMNFLEGKDFAAFVAKMKRGFWPALQMNWRVWTPVQFINVNYVPLQFRVLFANVVALFWYAYLASLGK-------------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q07066-1", "uniprot_id": "PXMP2_RAT", "id": "Q07066-1", "name": "Peroxisomal membrane protein 2", "aln": "-----------------------------------------------------MAPAASRLRVESELRSLPKRALAQYLLFLKFYPVVTKAVSSGILSALGNLLAQMIEKKQKKD--SRSLEVSGLLRYLVYGLFVTGPLSHYLYLFMEYWVP-PEVPWARVKRLLLDRLFFAPTFLLLFFFVMNLLEGKNISVFVAKMRSGFWPALQMNWRMWTPLQFININYVPLQFRVLFANMAALFWYAYLASLGK-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8C2MY14-1", "uniprot_id": "A0A8C2MY14_CRIGR", "id": "A0A8C2MY14-1", "name": "", "aln": "-----------------------------------------------------MAPAASRLRAECELPSLPRRALAQYLLLLKLYPVFTKAVSSGILSAVGNLLAQMIEKKQKND--SQSLDVSGLLRYLIYGFFVTGPLSHYFYLFMEYWIP-PGVPLATVKRLLLDRLLFAPTFLLLFFLIMNLLEGKDVSAFASKMRSGFWPALQMNWRMWTPLQFININYVPLQFRVLFANMAALFWYAYLASLRK-------------", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q54GD8-1", "uniprot_id": "PX24C_DICDI", "id": "Q54GD8-1", "name": "PXMP2/4 family protein 3", "aln": "-------------------------------------------------------------MSNSKPLSLTDAVTTWYMKKLKSKPIQTKALTSATLSFISSVVAQKFIEKKKIN-------WNAVVKFTVWGLISS-PLVHYWHIILDRLFKNIKDKYQSWGKLIVDQLVFAPFINIAFYSVLAILDGK-PKSILFKLYFDLFPTLKASWKVWPLAQLINFRFVPSHLRVLFGNLVGFCWGIYLSILATKKRN---------", "tax_id": 44689, "tax_name": "Social amoeba" }, { "uniprot_ac": "A0A0S0WGR0-1", "uniprot_id": "A0A0S0WGR0_DROME", "id": "A0A0S0WGR0-1", "name": "Peroxisomal membrane protein PMP22", "aln": "MTSTQSDQISQFLECHGTTPVPNSGTSEILKFVPSAKVVGSALSCESATKTFGVSQAHLCTTGNMVLSKPLYSLFGTYLEQLFNHPVRTKSITACVLATSANVTSQRLAGAKTLN-------QQSVFAYGLFGLIFGGSVPHYFYTTVERLFS-QDVRFRRFFLFLSERLVYAPIYQALSLFFLALFEGKSPSTALKNVEKLYWPLLKANWQYLSVFVYLNFAYVPPMFRSISMAIISFIWVVYIAQKRRRFQDKLAAKEAAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: * *: **: :: *: ... :* : :. : . . : ::*:: .: *: : :: . :: ::*.:** .: :::** :: :* *: .*: . :*. :** :* : : .: * *:: ", "identical_positions": 23, "similar_positions": 57, "identity": "8.75%" }, { "cls_id": "homologset.oma.816486", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9N8-1", "uniprot_id": "D4A9N8_RAT", "id": "D4A9N8-1", "name": "", "aln": "---------------MAAGGWRWARKALAAGRPLFQGRALLVTNTLGCGVLMATGDGARQAWEVRARPEQRFSARRSASMFAVGCSMGPFL-HFWYLWLDR--LLPASGLRSLPSVMKKVLVDQTVASPILGVWYFLGLGSLEGQTLEESCQELRAKFWDFYKADWCVWPAAQLVNFLFIPSHFRVTYINGLTLGWDTYLSYLKYWAPEPLQTPGCAD--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VIK2-1", "uniprot_id": "M17L2_MOUSE", "id": "Q8VIK2-1", "name": "Mpv17-like protein 2", "aln": "---------------MALGGWRWARKALAAGRPLFQGRALLLTNTLGCGVLMAAGDGARQVWEVRARPGQRFSARRSASMFAVGCSMGPFL-HFWYLWLDR--LLPASGLRSLPSVMKKVLVDQTVASPILGVWYFLGLGSLEGQTLEESCQELRAKFWDFYKADWCVWPAAQLVNFLFIPSHFRVTYINGLTLGWDTYLSYLKYWVPEPLQTPGCAD--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q567V2-1", "uniprot_id": "M17L2_HUMAN", "id": "Q567V2-1", "name": "Mpv17-like protein 2", "aln": "---------------MARGGWRRLRRLLSAGQLLFQGRALLVTNTLGCGALMAAGDGVRQSWEIRARPGQVFDPRRSASMFAVGCSMGPFL-HYWYLSLDR--LFPASGLRGFPNVLKKVLVDQLVASPLLGVWYFLGLGCLEGQTVGESCQELREKFWEFYKADWCVWPAAQFVNFLFVPPQFRVTYINGLTLGWDTYLSYLKYRSPVPLTPPGCVALDTRAD--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1S919-1", "uniprot_id": "F1S919_PIG", "id": "F1S919-1", "name": "", "aln": "MGWAAGAPVPGSQRTMASGGWRWLRSLLAAGQPLFQGRALLVTNTLGCGALMAAGDGVRQSWEIRARPGQKFDPRRSASMFAVGCSMGPFL-HYWYLWLDR--LLPASGFRGLPNVLRKVLVDQVVASPMLGVWYFLGLGCLEGQTLDESCQELRDKFWEFYKADWCVWPAAQLVNFLFVPPQFRVTYINGLTLGWDTYLSYLKYRVPSPLTPPGCVVLGTVQTELPPTPTRCQTGQD", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A5D787-1", "uniprot_id": "M17L2_BOVIN", "id": "A5D787-1", "name": "Mpv17-like protein 2", "aln": "---------------MPPGGWRWLRGLWAAGQPLFQGRALLVTNTLGCGVLMAAGDGARQTWEIRARPGQKFDPRRSVSMFAVGCSMGPFL-HYWYLWLDR--LFPASGFPGLPNVLKKVLIDQLVASPMLGVWYFLGLGCLEGQTLDKSCQELRDKFWEFYKADWCVWPAAQLVNFLFVPPQFRVTYINGLTLGWDTYLSYLKYRIPGPLTPPGCVALGTIQTEPPDARQQGKTD--", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q6DGV7-1", "uniprot_id": "M17L2_DANRE", "id": "Q6DGV7-1", "name": "Mpv17-like protein 2", "aln": "--------------MISRQGKEFLVRIAGYWKPLFRGRFLIVTNTVSCGGMLAAGDLIQQTREIRRTPGRTRDWSRTGCMFAVGCSMGPFM-HYWYQWLDK--YFIGNGIN---NVCKKVLVDQLVASPTLGAWYFLGMGMMEGHTFIEAQQEFRDKFWEFYKADWCVWPAAQMINFYFLPPKFRVLYVNIVTLGWDTYLSYLKHRDTVEVTKEADGTA-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06563-1", "uniprot_id": "SYM1_YEAST", "id": "Q06563-1", "name": "Protein SYM1", "aln": "------------------------MKLLHLYEASLK-RRPKTTNAIMTGALFGIGDVSAQLLFPTSKVNKGYDYKRTARAVIYGSLIFSFIGDKWYKILNNKIYMRNRPQYHWSNMVLRVAVDQLAFAPLGLPFYFTCMSIMEGRSFDVAKLKIKEQWWPTLLTNWAVWPLFQAINFSVVPLQHRLLAVNVVAIFWNTYLSYKNSKVMEKDKVPVHYPPVVE----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: * **:: * ::. ** * : . *: . *. : .*: . ** *:. : .: :* :** . :* :** :. :**::. : ::: ::* ::*.*** * :** .:* :.*: :* ::: *:***** : ", "identical_positions": 38, "similar_positions": 54, "identity": "15.97%" }, { "cls_id": "homologset.oma.816489", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MS3-1", "uniprot_id": "MP17L_MOUSE", "id": "Q99MS3-1", "name": "Mpv17-like protein", "aln": "MASWWRAFPQAARRYPWPTNVLLYAGLFSAGDALQQRLRGGPADWRQTRRVATLAVTFHGNFNYVWLRLLERALPGRAPRTVLAKVLCDQTVGGPIALSAFYVGMSVLQGKDDIFLDLKQKFWNTYKSGLMYWPFVQLTNFSLVPVHWRTAYTGLCAFLWATFLCFSQQSGDGTLQSIFIFLRRK--EASDKSPEK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2QL34-1", "uniprot_id": "MP17L_HUMAN", "id": "Q2QL34-1", "name": "Mpv17-like protein", "aln": "MAGWWPALSRAARRHPWPTNVLLYGSLVSAGDALQQRLQGREANWRQTRRVATLVVTFHANFNYVWLRLLERALPGRAPHALLAKLLCDQVVGAPIAVSAFYVGMSILQGKDDIFLDLKQKFWNTYLSGLMYWPFVQLTNFSLVPVQWRTAYAGVCGFLWATFICFSQQSGDGTFKSAFTILYTKGTSATEGYPKK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.** *:.:****:*********..*.**********:* *:**********.****.*******************:::***:****.**.***:********:******************* *******************:*****:*:*.******:**********::* * :* * .*:: *:*", "identical_positions": 152, "similar_positions": 32, "identity": "77.55%" }, { "cls_id": "homologset.oma.816491", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W588-1", "uniprot_id": "Q9W588_DROME", "id": "Q9W588-1", "name": "Mpv17-like protein", "aln": "MVPAAVKLLQASLGQWRRGSKLHPMAKGALTYAVMWPAGSLIQQAMEGRKLR-----EYDWARALRFSLFGALYVAPTLYGWVRLTSAMWPQTNLRTGIVKAITEQLSYGPFACVSFFMGMSLLELKTFSQAVEETKEKAAPTYKVGVCIWPILQTINFSLVPEHNRVVFVSICSLMWTIFLAYMKTHHEEQSNSAVLPCT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q54XX9-1", "uniprot_id": "PX24B_DICDI", "id": "Q54XX9-1", "name": "PXMP2/4 family protein 2", "aln": "----MRKLWGLYLGLLDN----HPLVTKSLSTGFLMGTGDILAQRLEHKFKDEKSQFKLDYKRVATMSTVGIFYSGPMLHYWYRSLDIMVKGEGRSVIIKKMLIDQLLFAPVAIGGFMTVTNFINNKGELKNLENFTKELFYAVKINWLIWPAAQIINFSLVPPNLRVLYSSIISIFWGMFLSHISFDKDHHIRNQNKEIN", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ** . **:.. :*: ..: :*.:: * :* : : *: *. :* .* :* .* *: * * . * . . * * : :** :.*.* .*: .::: * : :*: .:: : *:. *** * ******* : **:: ** *::* :**:::. .::.: .. .", "identical_positions": 49, "similar_positions": 64, "identity": "24.38%" }, { "cls_id": "homologset.oma.816495", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VZM6-1", "uniprot_id": "Q9VZM6_DROME", "id": "Q9VZM6-1", "name": "Mpv17-like protein 2", "aln": "MFGTRCLR-----QCYSLRIHGSHNS---RRDFAALCRMRSHGVGYQKYG--------------------LRFTHGKGETEGG--------------------ALSFILLRWTKIAWSN-MFGKYLLVTNVVGSGLLMVVGDVIAQEYEYRRGLRHQDRFDTDRMYRMFVAGALQGPLHHYVYNWMDRVMPARTLKNIFKKILIDQLVMSPACIVIFFYSLCYLERQTLDATNQELISKFPYVYMLDWMTWPAAQYLNFRYLDTKYRVTFVNVCTAVYNVLMSYMKHDFGVHLPLEEKLVASSEQNLLPQSSTTSPDAQKAV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "F4K2L8-1", "uniprot_id": "F4K2L8_ARATH", "id": "F4K2L8-1", "name": "", "aln": "MLNSITLTRKPPLPFNSVGFSGNHSSSFGRRTITEGSSSKALSFGYKNVGSLKCGRSNWPGRSGTAFGHLVRVSAVPGGNSGGSGGLGGSGGGGGGSGGGGGDGSDGKGKKWSLLSWYQALLSNSPVLTKAVTAALLNLVGDLICQLTINKTSSLDKKR----TLTFTFLGLGLVGPTLHFWYLYLSKVVTASGLSGAVIRLLLDQFVFAPIFVGVFLSAVVTLEGKPSNVIP-KLQQEWTGAMIANWQLWIPFQFLNFRFVPQNYQVLASNVVALAWNVILSFKAHKEVVAK-----------------------------", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.: * *: : *.*.* ** :: . :: ..**:: * :*.: * ..** . . :*: ::* : ::.: ::*:.* :.** :***:*.* : . .:.* : *:. .* ** *: * ::.:*:.* *.. . ::*:**:*::* : :*: :: ** :. :. :* .::. . : :* * . *:****:: :*:* ** : .:**::*: *. * ", "identical_positions": 61, "similar_positions": 96, "identity": "18.94%" }, { "cls_id": "homologset.oma.816499", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VN75-1", "uniprot_id": "Q9VN75_DROME", "id": "Q9VN75-1", "name": "", "aln": "--------------------------------------MFRS----------------------------------LVNITSKYKVLRGMISYGTLWPCGSLIEQTMIEKKTFRTYDWMKCLRFSLFGFFFMGPTIYVWIRLASVMWPRTDIKSSLCKAITEQTAYDPMAISSFLFFMTLMEGNSYAEAKREVSDKFLDAYKVGVIYWPCVQTVNFAFVPARNQVVFTSFFSMCWTTFLAYVKFLQLHPPVDVDHHALDIHFLEM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O82324-1", "uniprot_id": "O82324_ARATH", "id": "O82324-1", "name": "", "aln": "MSRALFRNVAVDTARLIRRNAAASTDQYGKTGVAQSRPYFRSRQLLERAKETGVSPSPSLGFSSSSSPSRIGFVGWYLGMVKSHPVVTKSVTSSLIYIAADLSSQTIAKTSSE-SYDLVRTARMGGYGLFVLGPTLHYWFNFMSRLFPKQDLITTFKKMAMGQTIYGPIMTVIFFSLNASLQGERGSVILARLKRDLLPALFNGVMYWPLCDFITFRFFPVHLQPLVSNSFSYVWTIYMTYMANREKPVAIST------------", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** :.:...: *: :: . :: ...* .**: :..: :** :: *:. :*:*.:***:: *:.: * ::*: *: ::: * ** *.*: *: : : ::*: : .:. .:* * **:*** : :.* *.*.: * :.:. ** ** :::*: : .:.. ", "identical_positions": 42, "similar_positions": 77, "identity": "15.85%" }, { "cls_id": "homologset.oma.816501", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IRC8-1", "uniprot_id": "Q8IRC8_DROME", "id": "Q8IRC8-1", "name": "Mpv17-like protein 2", "aln": "MMFSWTRLANPLKMSCQLVTHFSTAPPPNAKFWTKLFGKYLLLTNTIGSGLLLAIGDAIAQQYERFGEK-KAFDYSRSGCMMITG-SVIGPIQHGFYLLLDGVLPGTSGWGVLHKILVDQLIMSPIYIFLFFYVSSLLGGKSFVECNSELSEKFLYTWMLDCCFWPGLQYLNFRFLNSLYRVVFVNVANCVYVVLLSHIKYGVSNHDP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q54FR4-1", "uniprot_id": "PX24D_DICDI", "id": "Q54FR4-1", "name": "PXMP2/4 family protein 4", "aln": "------------------MSRLLVGLKLAQSHYLSQLHKYPVATKAVTSGFLYLISDSLVQGIELSRDKDKKYDFKRSMRMAVFGFAVTGPLFHYWFKYLDKHFPKKSYRHAFIKLTIDQVVCSPVFNFLFFSGMGILEGKSKDDIVEKLKKDWLTTYVSDCVVWPFINFVNFAYISSIHRVTFMNVCNIGWGAFLAKMN---SSH--", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::: .. ..: . : ** : *::: **:* *.*::.* * :* * :*:.** * : * :* **: * :: ** :* .* .: *: :**:: **:: **** .:* *** : .:*.:.:* *:: ** .** ::::** ::.*::**.*:**.* : .:*:::: *.* ", "identical_positions": 57, "similar_positions": 71, "identity": "27.4%" }, { "cls_id": "homologset.oma.816639", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BHX1-1", "uniprot_id": "HAUS1_MOUSE", "id": "Q8BHX1-1", "name": "HAUS augmin-like complex subunit 1", "aln": "---------------MAAPEEKALQVAEWLKKVFG--DHPIPQYEMNSRTTEILYHLSERNRVRDRDISLVIEDLKQKASEYESEAKRLEDFLMESVNFSPANLSKSGSRFLNALVDSAIALEIKDTSLASFIPAVNDLTSDLFRTKSKSEEMKLELGKLEKNLTATLVLEKCLREDLKKAELQLSAEKAKVDSRLQNMDFLKAKAAEFRFGIKAAEEQLSARG-MDASLSHRSLAALSEKLSELKEQTIPLKKKLESYLDLMPSPSLAQLKIEEAKRELDAIEAELTKKVDMMGL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R0A8-1", "uniprot_id": "HAUS1_RAT", "id": "Q9R0A8-1", "name": "HAUS augmin-like complex subunit 1", "aln": "---------------MAALEEKASQVAEWLKKIFG--DHPIPQYEMNARTTEILYHLSERNRVRDRDVNLVIEDLRQKASEYESEAKRLEDFLMESVNFSPANLSNTGSRFLNALVDSAIALEIKDTSLASFIPAVNDLTSDLFRTKSKSEEIKLELGKLEKNLTATLVLEKCLREDLKKADVHLSAERAKAEGRLQNMDFLKAKAAEFRFGIRAAEEQLSSRG-MDASLSHRSLVALSDKLSELKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDAIEAELTKKVDMMEL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1RPT0-1", "uniprot_id": "F1RPT0_PIG", "id": "F1RPT0-1", "name": "", "aln": "---------------MEAPEEKEAQVAAWLKKIFG--DHSIPQYEVNPRTTEILHHLAECNRVRDRDVCLVIEDLKQKAREYESEAKHLQDLLMESVNFSPANLSSAGSKYLNALVDSAVALETKDTSLASFIPAVNDLTSDLFRTKSKNEEIQLELGKLEKNLTAALVLEKCLREDLKKAELHLSMERAKVDNRLQNMDFLKAKAEEFRSGIRAAEKQLSARG-MDASLSHQSLVALSEKLAELKQQTMPLKKKLESYLDLMPNPSLAQVKIEEAKRELDTIEAELTKKVNMMEL----", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q2TBK4-1", "uniprot_id": "HAUS1_BOVIN", "id": "Q2TBK4-1", "name": "HAUS augmin-like complex subunit 1", "aln": "---------------MEALEEKEAQVAAWLKKIFG--DHPIPQYEVNAWTTEILYNLSERNRIRDRDVYLVTEDLKQKAKEYESEAKHLQDLLMESVNFSPASLSSTGSRYLNALVDSAVVLETKDTSLASFIPAVNDLTSDLFRTKSKNEEIKLELAKLEKNLTATLVLEKCLQEDLKKAELHLCTERARVDSRLQNMDFLKAKSEEFRSGIRTAEEQLSARG-MDASLSHQSLVALSEKLAELKRQTMPLKKKLESYLDLMPNPSLAQVKIEEAKRELDTIEAELTKRVNMMEL----", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q96CS2-1", "uniprot_id": "HAUS1_HUMAN", "id": "Q96CS2-1", "name": "HAUS augmin-like complex subunit 1", "aln": "---------------MEPQEERETQVAAWLKKIFG--DHPIPQYEVNPRTTEILHHLSERNRVRDRDVYLVIEDLKQKASEYESEAKYLQDLLMESVNFSPANLSSTGSRYLNALVDSAVALETKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAELHLSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARG-MDASLSHQSLVALSEKLARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDSIEAELTRRVDMMEL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QWF9-1", "uniprot_id": "F1QWF9_DANRE", "id": "F1QWF9-1", "name": "", "aln": "----------MQHTFTGNMCEKSKIVSQWLRKVFG--QQTVPEFEVNTRTVEILYELVQNSEMRCREAELLIQDHEQKTQEYSSDGAHLQEVLLQGVGLQTGGLSKPTVDLLSVLEGTAEVLKLRDTSLGSYMPALNKLTNDVLEAEKTDRRLQRELSAVRKKMTAAVVLRKKLQDDLIKVTHIQQVEAATAEERLLNMDFMRNKSRDLACRNKIAQEKLDSRQ-MEDSLTHQAILQLSEKIAALKEETLPLKKKLEPFSDLSPSPALARVKIEEAKRELAALDAQLEQKVDFMNTLSR-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F4IK01-1", "uniprot_id": "AUG1_ARATH", "id": "F4IK01-1", "name": "AUGMIN subunit 1", "aln": "MSDVTGDLAAVSEAKGGSDAARISEVKAWLTSQFEAVGKEVPNFEYTHRSITHLYNLATASQAKSQAATIVANDFRLKASEYRAQAARIREILES-AGMSQESLPSNVVSSAQVLANVANLLNIRDTELSSFLVAMGDISLRKTGVEEKRAKAQKESNALLDYTRKAIQRLTYLKKILAQLEDDVVPCESQMENWKTNLEVMAVKEEQYIQQYKKYEQMLLNRVGYTPKISHRELVEMAEHRKELDKMTKPVLDTLRSYQDLPPDKALAALAIEDKKRQFTAAEKYLEEVLQSALETNDE", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ** . * : :*::* . : *:.* .. : : :: :* . *: ** ::. :.:.* . ..:. .*.. ..* . * *: :**.*.*:: *:..:: .:.. . : * : . :: . *:. : : : : *::.: * : : :: * * .::*: : :::: *.. * *: ..*..: ** *. :** : **: **:: : : * . :: ", "identical_positions": 43, "similar_positions": 101, "identity": "14.33%" }, { "cls_id": "homologset.oma.816654", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZXI3-1", "uniprot_id": "D3ZXI3_RAT", "id": "D3ZXI3-1", "name": "", "aln": "--------------------------------------------------------------------MG-GEVRVLLLLGLLHWVGGSEGRKTWRRRGQQPPQPPPPPPPPQRAEVAPGAGQPVESFPLDFTAVEGNMDSFMAQVKSLAQSLYPCSAQQLNEDLRLHLLLNTSVTCNDGSPAGYYLKESKGSRRWLLFLEGGWYCFNRENCDSRYSTMRRLMSSKDWPHTRTGTGILSSQPEENPHWWNANMVFIPYCSSDVWSGASPKSEKNEYAFMGSLIIQEVVRELLVKGLSGAKVLLLAGSSAGGTGVLLNVDRVAELLEELGYPSIQVRGLADSGWFLDNKQYRRSDCIDTINCAPTEAIRRGIRYWSGMVPERCQRQFKEGEEWNCFFGYKIYPTLRCPVFVVQWLFDEAQLTVDNVHLTGQPVQEGQWLYIQNLGRELRGTLKDVQASFAPACLSHEIIIRSYWTDVQVKGTSLPRALHCWDRSFHDSHKASKTPMKGCPFHLVDSCPWPHCNPSCPTIRDQFTGQEMNVAQFLMHMGFDVQTVAQQQGMEPSKLLGILSSGN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R116-1", "uniprot_id": "NOTUM_MOUSE", "id": "Q8R116-1", "name": "Palmitoleoyl-protein carboxylesterase NOTUM", "aln": "--------------------------------------------------------------------MG-GEVRVLLLLGLLHWVGGSEGRKTWRRRGQQPPQPPPPPPLPQRAEVEPGAGQPVESFPLDFTAVEGNMDSFMAQVKSLAQSLYPCSAQQLNEDLRLHLLLNTSVTCNDGSPAGYYLKESKGSRRWLLFLEGGWYCFNRENCDSRYSTMRRLMSSKDWPHTRTGTGILSSQPEENPHWWNANMVFIPYCSSDVWSGASPKSDKNEYAFMGSLIIQEVVRELLGKGLSGAKVLLLAGSSAGGTGVLLNVDRVAELLEELGYPSIQVRGLADSGWFLDNKQYRRSDCIDTINCAPTDAIRRGIRYWSGMVPERCQRQFKEGEEWNCFFGYKVYPTLRCPVFVVQWLFDEAQLTVDNVHLTGQPVQEGQWLYIQNLGRELRGTLKDVQASFAPACLSHEIIIRSYWTDVQVKGTSLPRALHCWDRSFHDSHKASKTPMKGCPFHLVDSCPWPHCNPSCPTIRDQFTGQEMNVAQFLMHMGFDVQTVAQQQGMEPSKLLGMLSNGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P988-1", "uniprot_id": "NOTUM_HUMAN", "id": "Q6P988-1", "name": "Palmitoleoyl-protein carboxylesterase NOTUM", "aln": "--------------------------------------------------------------------MG-RGVRVLLLLSLLHCAGGSEGRKTWRRRGQQP-----PPP--PRTEAAPAAGQPVESFPLDFTAVEGNMDSFMAQVKSLAQSLYPCSAQQLNEDLRLHLLLNTSVTCNDGSPAGYYLKESRGSRRWLLFLEGGWYCFNRENCDSRYDTMRRLMSSRDWPRTRTGTGILSSQPEENPYWWNANMVFIPYCSSDVWSGASSKSEKNEYAFMGALIIQEVVRELLGRGLSGAKVLLLAGSSAGGTGVLLNVDRVAEQLEKLGYPAIQVRGLADSGWFLDNKQYRHTDCVDTITCAPTEAIRRGIRYWNGVVPERCRRQFQEGEEWNCFFGYKVYPTLRCPVFVVQWLFDEAQLTVDNVHLTGQPVQEGLRLYIQNLGRELRHTLKDVPASFAPACLSHEIIIRSHWTDVQVKGTSLPRALHCWDRSLHDSHKASKTPLKGCPVHLVDSCPWPHCNPSCPTVRDQFTGQEMNVAQFLMHMGFDMQTVAQPQGLEPSELLGMLSNGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A286ZU78-1", "uniprot_id": "A0A286ZU78_PIG", "id": "A0A286ZU78-1", "name": "", "aln": "--------------------------------------------------------------------MG-RGVRVLLLLGLLHWAGGGEGRKTWRRRGQQP-----PPPPPPRAEVAPAAGQPVESFPLDFTAVEGNMDSFMAQVKSLAQSLYPCSAQQLNEDLRLHLLLNTSVTCNDGSPAGYYLKESKGSRRWLLFLEGGWYCFNRENCDSRYDTVRRLMSSKDWPRTRTGTGILSSQPEENPHWWNANMVFIPYCSSDVWSGASSKSEKNEYAFMGALIIQEVVRELLGKGLSGAKVLLLAGSSAGGTGVLLNVDRVAEQLEELGYTAIQVRGLADSGWFLDNKQYRRTDCIDTITCAPTEAIRRGIRYWNGVVPERCRRQFKEGEEWNCFFGYKVFPTLRCPVFVVQWLFDEAQLTVDNVHLTGQPVQEGQWLYIQNLGRELRNTLKDVPASFAPACLSHEIIIRSHWTDVQVKGTSLPRALHCWDRSLHDSHKASKAPLKGCPVHLVDSCPWPHCNPSCPTIRDQLTGQEMNVAQFLMHMGFDVQTVAQQQGLEPSKLLGMLSSGS", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A8V1AKN4-1", "uniprot_id": "A0A8V1AKN4_CHICK", "id": "A0A8V1AKN4-1", "name": "", "aln": "MLAAWERAAGSCAGSRPAEPAPSALPSPPAADPRPRGRLGGARRSAGGVARHRGLAAAAARGGWRRAAMGTAAVHLLLLLGLLHAGPGGEGRKGWRRRG--------PAARERGEATAAAAAAPAESFPLDFTAVEGNMDSFMAQVKSLAQSLYPCSAQALPHDLRLHLLHNASVTCNDGSPAGYYLKESKGSRRWLLFLEGGWYCFNRENCDTRYDTMRRLMSSKEWPATRVGTGILSSQPEENPHWWNANMVFIPYCSSDVWSGASSKSEKNEYAFMGALIIQEVIKELVGKGLSTAKVLLLAGSSAGGTGVLLNVDRVAEQLEEMGYQGIQVRGLADSGWFLDNKQYRRTDCIDTITCAPTEAIRRGIRYWNGIVPERCKLQFKEGEEWNCFFGYKIYPTLRCPVFVVQWLFDEAQLTVDNVHLTGQPVQEGQWLYIQNLGRELRNTLKDVTASFAPACLSHEIITRNHWTDIQVKGTSLPRALHCWDRSLHESNKNGKAPLKGCPIHLIDSCPWPHCNPSCPTIRDQFTGQEMNVIQFLMHMGFDVQKMAQQQGLEPSKLLGMLSSGN", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "C5H5C4-1", "uniprot_id": "NOT1A_DANRE", "id": "C5H5C4-1", "name": "Palmitoleoyl-protein carboxylesterase notum1a", "aln": "---------------------------------------------------------------MKRSLWVMQVLHWAVMLALVQCGALGARR---FRGGRNP-----QPRRALPSAHYRDRGETTESFSLDFTAVEENMDNFMTQVKNLAQSLYPCSAQKLDYDMKLHFLENTSVTCNDGTPAGYYLKESKGSKRWLIFLEGGWYCFNKENCDSRYETMRRLMSSSKWPQTKTGTGMLSSLPEENPHWWNANMVFIPYCSSDVWSGASPKTDQNDYAFMGSLIIKEVVKDLLSKGLDNAKILLLAGSSAGGTGVLLNVDSVSELLEELGHTNIQVRGLSDSGWFLDNKQYRCTDCVDTINCAPTEVIKRGIKYWGGVVPERCRQAY-EGKEWNCFFGYKVYPTIKRPVFIVQWLFDEAQLTVDNIHLTGQPVQEGQWRYIQNLGTELRNTLKDVPAMFAPACLSHEFITRNYWTDVQVKGTSLPRALHCWDRSLQDTSRNNKSPPKGCPVHLIDSCPWPHCNPTCPTIRDQSTGQEMNVIQFLMHMGFDVQKMAHQQGMDPSKLLGMLSSGS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ::*.*:: . * * * . . ..***.******* ***.**:***.*********** * *::**:* *:*******:*********:**:***:**********:****:**.*:****** .** *:.***:*** *****:*********************.*:::*:*****:***:**:::*: :**. **:****************** *:* **::*: ******:************ :**:***.****:.*:***:**.*:*****: : **:*********::**:: ***:**************:********** ****** *** ***** * *********:* *.:***:*****************:::: : .*:* ****.**:**********:***:*** ******* *********:*.:*: **::**:***:**.*.", "identical_positions": 336, "similar_positions": 95, "identity": "58.74%" }, { "cls_id": "homologset.oma.816789", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NZF1-1", "uniprot_id": "PLAC8_HUMAN", "id": "Q9NZF1-1", "name": "Placenta-specific gene 8 protein", "aln": "---------------------------------------------------------MQAQAPVVVVTQPGVGPGPAPQNSNWQTGMCDCFSDCGVCLCGTFCFPCLGCQVAADMNECCLCGTSVAMRTLYRTRYGIPGSICDDYMATLCCPHCTLCQIKRDINRRRAMRTF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0M497-1", "uniprot_id": "A0ABK0M497_RAT", "id": "A0ABK0M497-1", "name": "", "aln": "MTKVKPLVDALKKKKKASLVCITFYVFVVTSNRRGIVTGSPGCLKSAPNLVFGDLELKMAQAATVIVTQPGFVR--APQNSNWQTSLCDCFSDCGVCLCGTFCFTCLGCQVAADMNECCLCGTTVAMRTLYRTRYGIPGSICDDYMVTLFCPVCSVCQIKRDINRRRAMNAF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3ZCB2-1", "uniprot_id": "PLAC8_BOVIN", "id": "Q3ZCB2-1", "name": "Placenta-specific gene 8 protein", "aln": "--------------------------------------------------------MQAASSPVVIVTQPGVGSGPAPQNSNWQTGLCDCFSDCGVCLCGTFCFTCLACQVASDMNECCLCGTSVAMRTLYRTRYGIPGSICDDFMVTHCCPLCSLCQIKRDINRRRANRTF", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1RVD7-1", "uniprot_id": "F1RVD7_PIG", "id": "F1RVD7-1", "name": "", "aln": "----ESLSS--HKTQPAQNLFLNYHSHLR-SCIQNASSGSSGHCDSARRWLHPS-NLQLADRLVRLLQR---LRRLHNETTVPTPPKQEHANPPTPSLCGIFCFSCLAVQVASDLNECCLCGTSVAMRTLYRTRYGIPGSICDDFMVTLCCPMCSLCQIKRDINRRRAMHTF", "tax_id": 9823, "tax_name": "Pig" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. . :: : :.: . : . .*** ***.**. ***:*:********:********************:*.* ** *::************ .:*", "identical_positions": 59, "similar_positions": 23, "identity": "34.3%" }, { "cls_id": "homologset.oma.816790", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A1L4L8-1", "uniprot_id": "PL8L1_HUMAN", "id": "A1L4L8-1", "name": "PLAC8-like protein 1", "aln": "MNWFGSNFFRCPEDLSLLNIYSP-LLSHMSSEDEHFISNLRGHVPASAVVKQPVRGASGRTTITAIVQTGGGWSTGLFSVCRDRRICFCGLFCPMCLECDIARHYGECLCWPLLPGSTFALRIGTRERHKIQGTLCEDWLAVHCCWAFSICQVARELKMRTSQVYEICAVPMTKDTLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RM19-1", "uniprot_id": "F1RM19_PIG", "id": "F1RM19-1", "name": "", "aln": "MSWFGNCFSRFPEDVSFLSTGSPLLLSLMSPEDEHLVSNLRSHASAQAVVKQPVRGASGRTTITAVVQTGGDWSTGLFSVCRDRRICFCGLFCPLCLECDIARHYGECFCWPLLPGSTFALRTGTRERHKIRGTLCEDWLAVHCCWPFSICQVARELKLRTSQTYEIYAARSTKETLI", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q08EJ0-1", "uniprot_id": "PL8L1_MOUSE", "id": "Q08EJ0-1", "name": "PLAC8-like protein 1", "aln": "MSWMGHHFSRWCKDISVLSSHLP-LFSPMPSEDEHLISNLRSHVPARVVVKQPIRGAIGRTTVAAIVQTGGDWSTGLFSVCRDRKICFWGLLCPMCLECDIARHYGECLCWPLLPGSTFALRIGTRERHRIQGTLCEDCVVVHCCWPFSICQVARELKMRTSQLYEICEVPELKNTLV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZTM1-1", "uniprot_id": "D3ZTM1_RAT", "id": "D3ZTM1-1", "name": "", "aln": "MSWLGHHFSRWCEDISLLSTHIP-LFSPMPSEDEHLISDLRSHVPACVVVKQPIRGASGRTTVTAIVQTGGDWSTGLFSVCRDRKICFWGLFCPMCLECDIARHYGECLCWPLLPGSSFALRIGTRERHKIQGTLCEDWVVVHCCWPFSICQVARELKMRTSQLYEICEVPELKDTLV", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.*:* * * :*:*.*. * *:* *..****::*:**.*..* .*****:*** ****::*:*****.************:*** **:**:*************:********:**** ******:*:****** :.*****.***********:**** *** . *:**:", "identical_positions": 122, "similar_positions": 35, "identity": "68.54%" }, { "cls_id": "homologset.oma.816791", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9LQU2-1", "uniprot_id": "PCR1_ARATH", "id": "Q9LQU2-1", "name": "Protein PLANT CADMIUM RESISTANCE 1", "aln": "----MEAQLHAKPHAQGEWSTGFCDCFSDCRNCCITLCCPCITFGQVAEIVDRGSKSCCAAGALYMLIDLITSCGRMYACFYSGKMRAQYNIKGDGCTDCLKHFCCNLCALTQQYRELKHRGFDMSLGWAGNAEKQQNQGGVAMGAPAFQGGMTR", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "E7F147-1", "uniprot_id": "E7F147_DANRE", "id": "E7F147-1", "name": "", "aln": "MAAISTTVVSTQRTSSGTWTTGICDCCSDMSTCCCGFWCFPCMQCQTASQFG------------WCFCMPLLDCCMVVSCCLRKKMREQYSINGSCCDDFCTLCFCYPCAWCQMSREIKTR---ARSGTTATVVTQQIRY---------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: :.* *:**:*** ** .** : * *.*. .. : : : .* : :* *** **.*:*. * * . * ** * **:* * * :... .** : ", "identical_positions": 36, "similar_positions": 31, "identity": "23.23%" }, { "cls_id": "homologset.oma.816792", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BYD5-1", "uniprot_id": "CNFN_HUMAN", "id": "Q9BYD5-1", "name": "Cornifelin", "aln": "-------------MSYPVTSQPQCATTSCYQTQLSDWHTGLTDCCNDMPVCLCGTFAPLCLACRISDDFGECCCAPYLPGGLHSIRTGMRERYHIQGSVGHDWAALTFCLP---CALCQMARELKIRE-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RGI5-1", "uniprot_id": "F1RGI5_PIG", "id": "F1RGI5-1", "name": "", "aln": "-------------MSYPVTSQPQCASG-CYQTQLSDWHTGLTDCCNDMPICLCGTFAPLCLACRISDDFGECCCAPYLPGGLHSLRTGMRERYHIQGSVGHDWAALTFCLP---CALCQMARELKIRE-----------------------------------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q6PCW6-1", "uniprot_id": "CNFN_MOUSE", "id": "Q6PCW6-1", "name": "Cornifelin", "aln": "-------------MSYPVTSQPQCANT-CYQTQLSDWHTGLTDCCNDMPVCLCGTFAPLCLACRISDDFGECCCAPYLPGGLHSLRTGMRERYHIQGSVGHDWAALTFCLP---CALCQMARELKIRE-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q0VBW2-1", "uniprot_id": "CNFN_BOVIN", "id": "Q0VBW2-1", "name": "Cornifelin", "aln": "-------------MSYPVTSQPQSAST-CYQTQLSDWHTGLTDCCNDMPVCLCGTFAPLCLACRISDDFGECCCTPYLPGGLHSLRTGMRERYRIQGSIGKDWAALTFCLP---CALCQMARELKIRE-----------------------------------", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0ABK0LTJ5-1", "uniprot_id": "A0ABK0LTJ5_RAT", "id": "A0ABK0LTJ5-1", "name": "", "aln": "MQFEMHDHVKGKAMSYPVTSQPQCTNT-CYQTQLSDWHTGLTDCCNDMPVCLCGTFAPLCLACRISDDFGECCCAPYLPGGLHSLRTGMRERYHIQVRAHPGPQGLRLGIAGVESRDCHLAPKSKAPDCSRFLSFPPSRAPSGTTGLLSPFVCPAPSVRWRGN", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **********.:. *********************:************************:*********:********:** . .* : :. . *::* : * : ", "identical_positions": 78, "similar_positions": 17, "identity": "47.85%" }, { "cls_id": "homologset.oma.816804", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JI48-1", "uniprot_id": "PLAC8_MOUSE", "id": "Q9JI48-1", "name": "Placenta-specific gene 8 protein", "aln": "---------MAQAPTVIVTQPGFVRAP----QNSNWQTSLCDCFSDCGVCLCGTFCFTCLGCQVAADMNECCLCGTTVAMRTLYRTRYGIPGSICDDYMVTLFCPVCSVCQLKRDINRRRAMNAF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3IA31-1", "uniprot_id": "G3IA31_CRIGR", "id": "G3IA31-1", "name": "", "aln": "---------MAQAPTVIVTQPGFVRAP----QNSNWQSSLCDCFSDCGVCLCGTFCFTCLGCQVAADMNECCLCGTTVAMRTLYRTRYGIPGSICEDFMVTLCCPVCSLCQIKRDINRRRAMNAF", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "A0A8V0XII3-1", "uniprot_id": "A0A8V0XII3_CHICK", "id": "A0A8V0XII3-1", "name": "", "aln": "TGADYRFLFWAESTRGTGRSSAFIGGETNLLQSARCLASLSSSSPSVHRGCCGLFCFPCLACTVAGDMNECCLCGTSVAMRTMYRTRYNIPGSICSDFCITSCCPVCSVCQIKRDINRRRAMGIF", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::. ...*: . *.:. :**... .. ** ***.**.* **.**********:*****:*****.******.*: :* *****:**:**********. *", "identical_positions": 61, "similar_positions": 29, "identity": "48.8%" }, { "cls_id": "homologset.oma.817062", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q13490-1", "uniprot_id": "BIRC2_HUMAN", "id": "Q13490-1", "name": "Baculoviral IAP repeat-containing protein 2", "aln": "MHKTASQRLFPGPSYQNIKSIMEDSTILSDWTNSNKQK--MKYDFSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQLYPSCSFIQNLVSAS-LGSTSKNTS-PMRNS------FAHSLSPTLEHSSLFSGSYSSLSPNPLNSRAVEDISSSRTNPYSYAMSTEEARFLTYHMWPLTFLSPSELARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEHRRHFPNCPFLEN--SLETLR-FSISNLSMQTH-----------AARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQLLSTSDTTGEENADPPIIHFGPGESSSEDAVMMNTPVVKSALEMGFNRDLVKQTVQSKILTTGENYKTVNDIVSALLNAEDEKREEEKE----KQAEEMASDDLSLIRKNRMALFQQLTCVLPILDNLLKANVINKQEHDIIKQKTQIPLQARELIDTILVKGNAAANIFKNCLKEIDSTLYKNLFVDKNMKYIPTEDVSGLSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRTFLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A3Q1N402-1", "uniprot_id": "A0A3Q1N402_BOVIN", "id": "A0A3Q1N402-1", "name": "", "aln": "---------------------MEDSTVLSNWTIGNKQK--MTYDFSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKQGDNPIEKHKQLYPSCSFIQNLVSVTSLESTSKNASSPMRNS------FTHSLSPTLEHGRSFSGSYSNLSPNPINSRAVEDFSPLRTNPYSYAMSTEEARFLTYQMWPLTFLSPSELARAGFYYIGPGDRVACFACGGTLNNWEPKDDAMLEHQKHFPSCPFLEN--SLETLR-FSISNLSMQTH-----------AARLRTFMYWPSTVSVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVSEIQARYPHLLEQLLSTANTSGDENADPPIVHFGPGESSSDDAVMMNTPVVKAALEMGFSRSLVKRTVQSKILTTGENYKTVNDIVSALLNAEDEKREEEKEEEKERQTEETASDDLSLLRRNRMALFQQLTCVLPILDNLLKANVINKQEHDIIKQKTQIPLQARELIDTVLVKGNSAASIFKNCLKEIDPTLYKNLFVEKNMKYIPT-DVSGLSLEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRTFLS", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A8V0XPA9-1", "uniprot_id": "A0A8V0XPA9_CHICK", "id": "A0A8V0XPA9-1", "name": "", "aln": "------------------MNIMDSSPLLASVMKQNAHCGELKYDLSCELYRMSTFSTFPVNVPVSERRLARAGFYYTGVQDKVKCFSCGLVLDNWQPGDNAMEKHKQVYPSCSFVQNMLSLNNLGLSTHSAFSPLVASNLSPSLRSMTLSPSFEQVGYFSGSFSSFPQDPVTTRAAEDLSHLRSKLHNPSMSTEEARLRTFHAWPLMFLSPTELAKAGLYYLGTADKVACFTCGGQLSNWEPKDNAMSEHRRHFPNCPFVEN--LMRDQPSFNVSNVTMQTH-----------EARVKTFINWPTRIPVQPEQLADAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWIEHAKWFPRCEYLLRVKGGEFVSQVQARFPHLLEQLLSTSDTPVDENMDP-IIHFEPGESPSEDAIMMNTPVVKAALEMGFSRRLIKQTVQSKILATEENYKTVNDLVSDLLTAEDEKREEEKE----RQFEEVASDDLSLIRKNRMALFQRLTSVLPILGSLLSAKVITELEHDVIKQKTQTPLQARELIDTVLVKGNAAASIFRNCLKDCDPVLYKDLFVEKSMKYVPTEDVSGLPMEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKECAPSLRKCPICRGTIKGTVRTFLS", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q24307-1", "uniprot_id": "DIAP2_DROME", "id": "Q24307-1", "name": "Death-associated inhibitor of apoptosis 2", "aln": "---------------------------------------MTELGMELESVRLATFGEWPLNAPVSAEDLVANGFFATGNWLEAECHFCHVRIDRWEYGDQVAERHRRSSPICSMVLAPNHCG------------------------------------------NVPRSQESDNEGNSVVDSPESCSCPDLLLEANRLVTFKDWPNPNITPQALAKAGFYYLNRLDHVKCVWCNGVIAKWEKNDNAFEEHKRFFPQCPRVQMGPLIEFATGKNLDELGIQPTTLPLRPKYACVDARLRTFTDWPISNIQPASALAQAGLYYQKIGDQVRCFHCNIGLRSWQKEDEPWFEHAKWSPKCQFVLLAKGPAYVSEVLATTAANASSQPATAPAP-----------------TLQADVLMDEAPAKEALALGIDGGVVRNAIQRKLLSSGCAFSTLDELLHDIFDDAGAG------------------------------------AALEVREPPEPSAPFIEPCQATTSKAASVPIPVADSIPAKPQAAEAVANISK--------------ITDEIQKMSVATPNGNLSLEEENRQLKDARLCKVCLDEEVGVVFLPCGHLATCNQCAPSVANCPMCRADIKGFVRTFLS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:. * *::*:. :* ..*** . *. **: ** :.:*. * : :*.*: **. ::*:: * **:: ... . . . :.. . : * *: *:: ** ::* **:**:**:. *:* *. *.* : :** :*:*: **::.**.** :: :. .:.:: :*. **::** ** .. **.**:** .*:*:** *: ***.*:. *:**.***** *:*:::: ** :*.:: . . .. :*: :. . : ::*: . .* ** :*:. :::.::* *:*:: :.*::::: :: . ..* : : : : : .: :. *: . : * : .::.*.* : :.:: * : ..*.:**: *:*:: * ****:*:**.:**:*****..*::****: :**:**. *** ******", "identical_positions": 138, "similar_positions": 179, "identity": "21.36%" }, { "cls_id": "homologset.oma.817064", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R0I6-1", "uniprot_id": "XIAP_RAT", "id": "Q9R0I6-1", "name": "E3 ubiquitin-protein ligase XIAP", "aln": "-------------MTFNSFEGSRTVVPADTN-----KDEEFVEEFNRLKTFANFPSSSPVSASTLARAGFLYTGEGDTVQCFSCHAAVDRWQYGDSAVGRHRRISPNCRFING-FYFENGATQSTSPGIQNGQYKSENCVGNRNH-FALDRPSETHADYLLRTGQVVDISDTIYPRNPAMCSEEARLKTFQNWPDYAHLSPRELASAGLYYTGIDDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNV-NVRSES-GVSSDRNFPNSTNSPRNPAMAEYDARIVTFGTWLYSVNKE--QLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLDEKGQEYINNIHLTHSLGESVVRTAEKTPSVTKKIDDTIFQNPMVQEAIRMGFNFKDIKKTMEEKLQTSGSNYLSLEVLIADLVSAQKDNSQDESSQTS-LQKDISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCCTVITFKQKIFMS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60989-1", "uniprot_id": "XIAP_MOUSE", "id": "Q60989-1", "name": "E3 ubiquitin-protein ligase XIAP", "aln": "-------------MTFNSFEGTRTFVLADTN-----KDEEFVEEFNRLKTFANFPSSSPVSASTLARAGFLYTGEGDTVQCFSCHAAIDRWQYGDSAVGRHRRISPNCRFING-FYFENGAAQSTNPGIQNGQYKSENCVGNRNP-FAPDRPPETHADYLLRTGQVVDISDTIYPRNPAMCSEEARLKSFQNWPDYAHLTPRELASAGLYYTGADDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNV-NVRSES-GVSSDRNFPNSTNSPRNPAMAEYEARIVTFGTWTSSVNKE--QLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLDEKGQEYINNIHLTHSLEESLGRTAEKTPSLTKKIDDTIFQNPMVQEAIRMGFSFKDIKKTMEEKIQTSGSSYLSLEVLIADLVSAQKDNTEDESSQTS-LQKDISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P98170-1", "uniprot_id": "XIAP_HUMAN", "id": "P98170-1", "name": "E3 ubiquitin-protein ligase XIAP", "aln": "-------------MTFNSFEGSKTCVPADIN-----KEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFING-FYLENSATQSTNSGIQNGQYKVENYLGSRDH-FALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNL-NIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKE--QLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTPSLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKDSMQDESSQTS-LQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0YRF2-1", "uniprot_id": "A0A8V0YRF2_CHICK", "id": "A0A8V0YRF2-1", "name": "E3 ubiquitin-protein ligase XIAP", "aln": "-------------MTCNGPDSSESGATPATD-----GDQEWTQEHYRLGTFVEFPHDCPVSASALARAGFVYTGEGDKVKCFSCHVTVEGWEPGDSAIDRHKNLSPDCRFITGSAFLEN----NVHPPVQSHQHRTENGSSNLALPSALEDLSDVEADYLLRTRQVVDMSDTLYPKNPAMCSEEARLKSFHNWPPYGLLTPKELASAGLYYTGVGDQVACFCCGGKLKNWEPGDRAWSEHKRHFPKCFFVLGRDVGNVSTDSICAELGRSCLNNEQHPRNPSMAEYERRIQTFLAWIYPVNKE--HLAEAGFYSTGNGDHVVCFHCGGGLQEWKENEDPWDQHAKWFPGCKFLRDEKGLEFINNVHLRDGCRDSTIEAAEVT-ILPK---DDLLQNQLVQNAIHMGFSLSEIRSIMEKKLHLSGESYTSVEDLVADLISAQKENIKGEPPKESPLEQDLSIEEKLRRLQEEKLCKICMAKDISVVLIPCGHLVACKECAEAVNKCPLCCTNIIKRQKIFMY", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q24306-1", "uniprot_id": "DIAP1_DROME", "id": "Q24306-1", "name": "Death-associated inhibitor of apoptosis 1", "aln": "MASVVADLPSYGPIAFDQVDNNTNATQLFKNNINKTRMNDLNREETRLKTFTDWPLD-WLDKRQLAQTGMYFTHAGDKVKCFFCGVEIGCWEQEDQPVPEHQRWSPNCPLLRR----------RTTNNVPINAEALDRILPPISYDICGANDSTLEMREHAYAEGVIPMSQLIQSIG--MNAVNAAGSVTGTAAPQPRVTVATHASTATQATGDVQPETCRPS-----------------------------------------------AASGNYFPQYPEYAIETARLRTFEAWPRNLKQKPHQLAEAGFFYTGVGDRVRCFSCGGGLMDWNDNDEPWEQHALWLSQCRFVKLMKGQLYIDTVAAKPVLAEEKEESSSIG-----------------------GVAVASTQASEEEQQTSLSSEEAVSGDVAPSVAPTAATRIFNKIVEATAVATPSTNSSGSTSIPEEKLCKICYGAEYNTAFLPCGHVVACAKCASSVTKCPLCRKPFTDVMRVYFS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : :.. . . : :: .* ** **.::* . :. **::*: :* **.*:** * . : *: *..: .*:. **:* :: . : :. . . . : *: :*: : . . * : :* . . . :: **:. ** : * . .. *: * * *: ** :* :::: :**.***: * **:* ** ***** :*: .::**:*** * . *::: ** :*:.: : .::. *. . . : *:: ... : ..: : .: : : : : .. : ******** : .::****:*:* :**.:* ***:* . : :::: ", "identical_positions": 88, "similar_positions": 132, "identity": "16.89%" }, { "cls_id": "homologset.oma.817065", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A690-1", "uniprot_id": "D4A690_RAT", "id": "D4A690-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MFSPAGLLRAAVLPMGPESKDRDSFCGPELSHREESNGPTQEQHRPHCPCNRVLGQD------CLDGQILGQLRPLSEEEE--SSGATFVGEPAFPEMDSEDLRLASFYDWPSTAGIQPEPLAAAGFFHTGQQDKVRCFFCYGGLQSWERGDDPWTEHARWFPRCQFLLRSKGRDFVERIQA-YTPLLGSWEQREEQEDTVSATPSAPTHGSPELLRSRRETQSEDASEPG------------------AEDVQEQLRQLQEERRCKVCLDRAVSVVFVPCGHFVCTECAPNLRLCPICRVPICNCVRTFLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AWP0-1", "uniprot_id": "BIRC7_MOUSE", "id": "A2AWP0-1", "name": "Baculoviral IAP repeat-containing protein 7", "aln": "MFSPADLFRAAVFSMGPESRARDSVRGPELSHREDGSGRTQEQDKPHCPCNHVLGQD------CLDGQILGQLRPLSEEEE--SSGAAFLGEPAFPEMDSEDLRLASFYDWPSTAGIQPEPLAAAGFFHTGQQDKVRCFFCYGGLQSWERGDDPWTEHARWFPRCQFLLRSKGRDFVERIQT-YTPLLGSWDQREEPEDAVSATPSAPAHGSPELLRSRRETQPEDVSEPG------------------AKDVQEQLRQLQEERRCKVCLDRAVSIVFVPCGHFVCTECAPNLQLCPICRVPICSCVRTFLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A3L7HGU0-1", "uniprot_id": "A0A3L7HGU0_CRIGR", "id": "A0A3L7HGU0-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MFSPEDLLRAAVLSMGPEGRARDLFCSPELSHREDSNSLTQEQYRSHRRRSHVSGQD------CLDGQILGQLRPLSEEEE--STGATFLGEPAFPEMDSEDLRLASFFDWPSTAGIQPEPLAAAGFFHTGQQDKVRCFFCYGGLQSWEHGDDPWTEHARWFPRCQFLLQSKGRDFVERIQA-CTPLLGSWDPWEEPEDTVPATATAPAHGGPELLASRRETQPEDASEPG------------------AGDVQAQLRQLQEERTCKVCLDRAVSVVFVPCGHLVCTECAPNLQVCPICREPISSCVRTFLS", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q96CA5-1", "uniprot_id": "BIRC7_HUMAN", "id": "Q96CA5-1", "name": "Baculoviral IAP repeat-containing protein 7", "aln": "--------------MGPKDSAKCLHRGPQPSHWAAGDGPTQERCGPRSLGSPVLGLDTCRAWDHVDGQILGQLRPLTEEEEEEGAGATLSRGPAFPGMGSEELRLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGDDPWTEHAKWFPSCQFLLRSKGRDFVHSVQETHSQLLGSWDPWEEPEDAAPVAPSVPASGYPELPTPRREVQSESAQEPGGVSPAEAQRAWWVLEPPGARDVEAQLRRLQEERTCKVCLDRAVSIVFVPCGHLVCAECAPGLQLCPICRAPVRSRVRTFLS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:. : .*: ** ... ***: .: . * * * :***********:**** .:**:: **** *.**:******:*** ** : ** **********:****************::*********:*** *****:*******. :* : *****: ** **:...:.:.*: * *** .***.*.*...*** * **: ***:***** **********:*******:**:****.*::***** *: . ******", "identical_positions": 169, "similar_positions": 56, "identity": "54.17%" }, { "cls_id": "homologset.oma.817066", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JTI9-1", "uniprot_id": "A0A0G2JTI9_RAT", "id": "A0A0G2JTI9-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MAKQWGISLVVKLTKSHEQNYLPGERLLPSPPCRLTMNMVQGSAFLAKLMKSADTFELKYDFSCELYRLSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFSCGLMLDNWKQGDSPIEKHRKLYPSCSFVQTLNPANSLEASPQPPLPSTATSTMPSGFAASESTGYFSGSYSSFPSDPVNFRANQDCPAFSTSPYHFAMNTEKARLLTYQTWPLSFLSPAELAKAGFYYTGPGDRVACFACGGKLSNWDRKDDPLSEHRRHFPSCPFLKDVGQFTSQYTVSNLSMQTHAARVRTFSTWPSSALVHPQELASAGFYYTGHSDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEYLIRIKGQEFVGQVQAGYPHLLEQLLSTSDSPEDETGEAAIVHLGPGE-NWEDAVMMNTPVVKAALDMGFSRSLVRQTVQRQILATGENYRTVSDLVIGLLDAEDEMREEQTEQEAEEEESDDLTLIRKNKMVLLQHLTPVTPILDCLLSARVITEQEYDAVKQKPHT-LQARTLIDTVLAKGNTAATSFRNSLQEIDPGLYRDIFVRQNIRSLPTDDIAALPMEEQLRKLQEERTCKVCMDREVSLVFIPCGHLVVCKECAPSLRKCPICRGTIKGTVRTFLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08863-1", "uniprot_id": "BIRC3_MOUSE", "id": "O08863-1", "name": "Baculoviral IAP repeat-containing protein 3", "aln": "--------------------------------------MVQDSAFLAKLMKSADTFELKYDFSCELYRLSTYSAFPRGVPVSERSLARAGFYYTGANDKVKCFCCGLMLDNWKQGDSPMEKHRKLYPSCNFVQTLNPANSLEASPRPSLPSTAMSTMPLSFASSENTGYFSGSYSSFPSDPVNFRANQDCPALSTSPYHFAMNTEKARLLTYETWPLSFLSPAKLAKAGFYYIGPGDRVACFACDGKLSNWERKDDAMSEHQRHFPSCPFLKDLGQSASRYTVSNLSMQTHAARIRTFSNWPSSALVHSQELASAGFYYTGHSDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEYLLRIKGQEFVSQVQAGYPHLLEQLLSTSDSPEDENADAAIVHFGPGE-SSEDVVMMSTPVVKAALEMGFSRSLVRQTVQWQILATGENYRTVSDLVIGLLDAEDEMREEQMEQAAEEEESDDLALIRKNKMVLFQHLTCVTPMLYCLLSARAITEQECNAVKQKPHT-LQASTLIDTVLAKGNTAATSFRNSLREIDPALYRDIFVQQDIRSLPTDDIAALPMEEQLRKLQEERMCKVCMDREVSIVFIPCGHLVVCKDCAPSLRKCPICRGTIKGTVRTFLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13489-1", "uniprot_id": "BIRC3_HUMAN", "id": "Q13489-1", "name": "Baculoviral IAP repeat-containing protein 3", "aln": "------------------------------------MNIVENSIFLSNLMKSANTFELKYDLSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLYPSCRFVQSLNSVNNLEATSQPTFPSSVTNSTHSLLPGTENSGYFRGSYSNSPSNPVNSRANQDFSALMRSSYHCAMNNENARLLTFQTWPLTFLSPTDLAKAGFYYIGPGDRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIENQLQDTSRYTVSNLSMQTHAARFKTFFNWPSSVLVNPEQLASAGFYYVGNSDDVKCFCCDGGLRCWESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESSIIHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYRLVNDLVLDLLNAEDEIREEERERATEEKESNDLLLIRKNRMALFQHLTCVIPILDSLLTAGIINEQEHDVIKQKTQTSLQARELIDTILVKGNIAATVFRNSLQEAEAVLYEHLFVQQDIKYIPTEDVSDLPVEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCAPSLRKCPICRSTIKGTVRTFLS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:.* **::*****:*******:******:****:** ******************.*******.*********:**** ***:****** ***:**..*.***:.:*.:**:. .: :..:*.:*** ****. **:*** ***** .*: *.** ***.*:*****::****:****:.******** ***********.******: **:.:*** ****.***::: * :*:**************.:** .****.**:.::********.*:************************:***********:*******: ****.*************** **..:::*:*: *** **.:**.***::**::********:**** :********* *.***:.**:****:***: *: :**:**:** *****:*.*:**** * *:* .**:* *.*** :.:***.:* *** ****:*.*** *** *****:* :. **..:**:*:*: :**:*:: **:*****:***** ******:***:************:************.***********", "identical_positions": 424, "similar_positions": 128, "identity": "66.25%" }, { "cls_id": "homologset.oma.817067", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q62210-1", "uniprot_id": "BIRC2_MOUSE", "id": "Q62210-1", "name": "Baculoviral IAP repeat-containing protein 2", "aln": "MDKTVSQRLGQGTLHQKLKRIMEKSTILSNWTKESEEKMKFDFSCELYRMSTYSAFPRGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKQGDSPVEKHRQFYPSCSFVQTLLSASLQSPSKNMSPVKSRFAHSSPL-ERGGIHSNLCSSPLNSRAVEDFSSRMDPCSYAMSTEEARFLTYSMWPLSFLSPAELARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEHRRHFPHCPFLENTSETQRFSISNLSMQTHSARLRTFLYWPPSVPVQPEQLASAGFYYVDRNDDVKCFCCDGGLRCWEPGDDPWIEHAKWFPRCEFLIRMKGQEFVDEIQARYPHLLEQLLSTSDTPGEENADPTETVVHFGPGESSEDVVMMSTPVVKAALEMGFSRSLVRQTVQRQILATGENYRTVNDIVSVLLNAEDERREEEKERQTEEMASGDLSLIRKNRMALFQQLTHVLPILDNLLEASVITKQEHDIIRQKTQIPLQARELIDTVLVKGNAAANIFKNSLKEIDSTLYENLFVEKNMKYIPTEDVSGLSLEEQLRRLQEERTCKVCMDREVSIVFIPCGHLVVCQECAPSLRKCPICRGTIKGTVRTFLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A9J7FXL1-1", "uniprot_id": "A0A9J7FXL1_CRIGR", "id": "A0A9J7FXL1-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MHTALSQRVVQGTLRQNPTSIMENSTTLPDWTRESKEKMKYDFSCELYRMSTYSAFPTGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKQGDSPVEKHRQLYPSCSFVHTLLSANLQSPSKNTAPVRSGLAHSLPIPERAGTHSNLSSNPLNSRAVEDLSSRTNPCSYAMITEEARFLTYSMWPLSFLSPAELARAGFYYVGPGDRVACFACGGKLSNWEPKDDAMSEHRRHFPNCPFLENSSETQRFSISNLSMQTHTARMRTFLCWPSSVPVQPEQLASAGFYYVDRNDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQARYPHLLEQLLSTSDTPGEENGNP--PIMHFGLGESSEDVVMMNTPVVKAALEMGFSRSLVRQTVQSQLLATGENYKTVSDIVSALLNAEGERRDEEEDRQTEEPASGDLSLIRKNRMALFQQLTCVLPILDNLLEASVITKQEHDIIRQKTQIPLQARELIDTVLVKGNAAANIFKNCLKEIDSTLYENLFVEKNMKYIPTEDVSGLSLEEQLRRLQEERTCKVCMDREVSIVFIPCGHLVVCQECAPSLRKCPICRGTIKGTVRTFLS", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*..::***: ****:*: . ***:** *.:**:**:****:**************** ***********************************************:*******:*****.******* :**:* :*** *: **.* ****.*.*********:*** :****** *****************************:*********************************:******:****************:**:**** **.************************************.*****:**********************************************.:* .::*** **********.********************** *:*******:**.****.*****.***:**::***** ******************** ****************************************************.*******************************************************************************************", "identical_positions": 545, "similar_positions": 49, "identity": "88.91%" }, { "cls_id": "homologset.oma.817177", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P10686-1", "uniprot_id": "PLCG1_RAT", "id": "P10686-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "aln": "MAGVGTPCANGCGPSAPSEAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADK-----IEGSIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAATPLQIERWLRKQFYSVD----------RNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDFEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLETNTLRTGERPELCQVSLSEFQQFLLEYQGELWA--VDRLQVQEFMLSFLRDPLREIEEPYFFLDELVTFLFSKENSVWNSQLDAVCPETMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQHFRKVLGDTLLTKPVDIAADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSV---------------MYSEND---ISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETS-SDQGNEDEE----------------EPKEASGSTELHSSEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIG--TAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQDGGWWRGDYGGKKQLWFPSNYVEEMINPAILEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSISMPSVAQWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMAGGHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCVICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAK-ENGDLSPFSGTSLRERASDASSQLFHVRAREGSFEARYQQPFEDFRISQEHLADHFDSRERRAP----RRTRVNGD---NRL-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62077-1", "uniprot_id": "PLCG1_MOUSE", "id": "Q62077-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "aln": "MAGVATPCANGCGPGAPSEAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADK-----IEGSIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAATPLQIERWLRKQFYSVD----------RNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLETNALRTGERPEHCQVSLSEFQQFLLEYQGELWA--VDRLQVQEFMLSFLRDPLREIEEPYFFLDELVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQHFRKVLGDTLLTKPVDIAADGLPSPNQLRRKILIKHKKLAEGSAYEEVPTSV---------------MYSEND---ISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETS-SDQGNEDEE----------------EPKEASSSTELHSSEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIG--TAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQDGGWWRGDYGGKKQLWFPSNYVEEMINPAVLEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSISMPSVAQWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMAGGHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCVICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAK-ENGDLSPFSGISLRERASDASSQLFHVRAREGSFEARYQQPFEDFRISQEHLADHFDSRERSTSDGPSSATNLIEDPLHDKLWKCSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19174-1", "uniprot_id": "PLCG1_HUMAN", "id": "P19174-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "aln": "MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADK-----IEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVD----------RNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRAGERPELCRVSLPEFQQFLLDYQGELWA--VDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSM---------------MYSEND---ISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETS-SDQGNEDEE----------------EPKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIG--TAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFIKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAK-ENGDLSPFSGTSLRERGSDASGQLFHGRAREGSFESRYQQPFEDFRISQEHLADHFDSRERRAP----RRTRVNGD---NRL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1SDV6-1", "uniprot_id": "F1SDV6_PIG", "id": "F1SDV6-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma", "aln": "MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADK-----IEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAATPLQIERWLRKQFYSVD----------RNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTELEQRSSDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRAGERPELCRVSLPEFQQFLLEYQGELWA--VDRLQVQEFMLSFLRDPLREIEETYFFLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVDIAADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSV---------------MYSEND---ISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETS-SDQGNEDEE----------------EPKEASSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLVSYYEKHPLYRKMKLRYPINEEALEKIG--TAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQRDDELTFTKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVSPAALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMAGGHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCAICVEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSIKQKTEFVVDNGLNPVWPAKLFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKLDIFPVKQENSDLSPFGGTSLRERGYDISGQPAHGRAREGSFEARYQQPFEDFRISQEHLADHFDSRERRAP----RRTRVNGD---NRL-----", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q9VXH3-1", "uniprot_id": "Q9VXH3_DROME", "id": "Q9VXH3-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma", "aln": "-----MSCFS--AMSAPLLGEMEQTIGMLERGTIVTKLYGKQ-RRPDRRHLMLIRETRQLLWATVATQTPRTDYEGAIQLREIREIRVGKHSKEFRLFADD-CQRFESSKCFVILHGNHFKLKSFSVVALSEIEADNWVRGLRYMVKDTLGAPYPLQIDRWLRREYYQIENVNTHSAKATEQSPAQVTIKDFKLFLAGVSCKMTTGKFM-EHFTEDVRRKHDLKFDDFSRLYQKLLLPNGFASVLSGSGVANFPYSEDQQVVRP--AELKQFLETEQRDVSASEISSAAIASFIRDFVQDVERDVQEPYLTFPEFVDFLFSKQNDLWNSKYDQVFMD-MNLPLSSYWIASSHNTYLTGDQFSSESSCEAYARALRMGCRCIELDCWNGPDNLPYIFHGHTITSKIKFMDVIKTIKDHAFTSSEYPVILSIEQNCSLEQQRNMAQALIEVFGDMLLTQPCDRNEQHLPSPYQLRRKIILKHKKLPQFDDIANGISSTGSLGHRSSLGGAGGGAHGENDGENVRKVFKEGLLYFKDPVDKSWNLYQFVLTHQELIYSSEINESRNGNSEDDDFGLSSSCSLNSNMQQKQKDTSANDELHFGENWFHGKLEGGRKE---ADDLLKKYKHFG---DGTFLVRESATFVGDYSLSFWRRNRPNHCRIKLKHENGSIKYYLVENFVFDSLYSLIVYYRKNMLRSSEFSIILKEPVPQPKKHEDQEWFHPNTTKEQAEQGLYRLEIG-SFLVRPSVQSINAFVISFTINRKIKHCRIMQEGRLYGIDTMNFESLVSLINYYTRNPLYRNVKLSHPVSQELLRQALAEAAQGDHSGGHDDNGASNYMGSNLEENVTC--KALYSYKANKPDELSFPKHAIITNVQRDNSMWWIGDYGGMIKKHLPANYVKVIDS---TTEDYNSLNEEG--TDGRTDSIEIFGAVASLFESNDPGIIFKLQIQTP-TMQNPFVIGFDNQETAYEWIKAIQEAALIASQLASERRKKERTARVAKEMSDLIIYFRSVPFREHSW-----IFQEMSSFPETKAEKQFFQQNTQLFLSYHRNQISRVYPKGQRLDSSNFNPMPFWNVGSQMIALNYQTGDKAMQLNQAKFRNNGQCGYILKPSFMKSDSFNPNN-PLCDGLSEVKVSIRLIAARHLFRGGK-SNNPQIVVELIGASFDTGVKYRTKVNENGFNPVWNES-CEFNVRNPQFAILRFEVQDEDMFAETHFIAQACYPLTCIRQGYRSVILRNKFSEELELSSLLINIKIANVT------AP--------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* . . .** .*: : ** **::* :*.*: :**:*: : : ****: *: * : **:*::***:*** ** *::* : :* . * :.*:*****:* .*:**::*: * ** *.: *::** ::::*** *. ****:****:::*.:: .: ::: **:* :*: *. ::.. :*: *::*: :*. *:.:.:*::**:.*: . : *. . : .* : : .*::*** * :: * :. : .*: .*::* *:::*.*: : *:* *****:*.:***: * * : ** *** ***:***************** *****.*************:***.:* *:****:*:**** **::***:***.:**********::**: ******* : :*:** ***:* : : **** **:***::*****.: . : :* :.*** : : :*:*:**::***::.* : **** .:: **.* . * :**.::: : *:.*.. *** .*:****** .**. *: **.:* **:****** ******:*****..: :****: ::: *: *::*.:*:******.**.:*:: **..**.: *.*****.: **.:**:*.. *: ***: * *: . :**** . :. *::.*** : ******: ***: :.. :*:***.*:.** ::****::** :*:.:* *.: :*: *:.. ::..... *: :* ...* ***:.***:: ***:* * *** **::::. ** ***** : :*:***: : . : : *:*:. * . ::: .. :: ... . :* :.*. . . : .: :. *.** :*:* *:*.* *. :* : ** ::* *:*:*::* *.*** *.. :::*********** . : : : **.*:* *:**:***********::*:*:* ***::***:** **.**:*** * . :***:*:** *:.::*:* : . **. :.:.::.**** :.*: * : :*: **.:*: : * :**:**** . .*:: **:**:*** * :****:: :*:*** :*:. :: ***:* *:*::**:***:****::.* .. :* ", "identical_positions": 512, "similar_positions": 404, "identity": "37.7%" }, { "cls_id": "homologset.oma.817178", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CIH5-1", "uniprot_id": "PLCG2_MOUSE", "id": "Q8CIH5-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2", "aln": "-MTTMVNVDTLPEYEKSQIKRALELGTVMTVFNARKSTPERRTVQMIMETRQVAWSKTADKIEGFLDIMEIKEIRPGKNSKDFERAKA--VRHKAECCFTILYGTQFVLSTLSLATDSKEDAVKWLSGLKILHQEAMSASTPTMIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVSGIKFLKDKLVEIGAQKDELSFEQFHLFYKKLMFDQQKSILDEFKKDSSVFILGNTDRPDASAVYLQDFQRFLLHEQQELWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRAGCRCIELDCWDGPDGKPIIYHGWTRTTKIKFDDVVQAIRDHAFVTSSFPVILSIEEHCSVEQQRHMAKVFKEVLGDMLLTKPTEASADQLPSPSQLREKIIIKHKKLGPKGDVDVNVEDKKDEHKPQGELYMWDSIDQKWTRHYCAIADAKLSFGDDIEQAVEEEPVQDTPPTELHFGEKWFH-KKVESRTSAEKLLQEYCAETGAKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMENGVMKYYLTDNLTFNSIYALIQHYREAHLRCAEFELRLTDPVPNPNPHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGTNSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDYKAKRSDELTFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISAGDAEEMEKQIIEDNPLGSLCKGILDLNTYNVVKAPQGKNQKAFVFILEPKKQGDPPVEFATDRVEELFEWFQSIREITWKMDTKENNMKYWERNQSIAIELSDLVVYCKPTSKTKDHLENPDFREIRSFVETKADSIVRQKPVDLLRYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKYMQMNHALFSLNGRTGYVLQPESMRSEKYDPMPLESQRKILMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDSNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCRQLRRRQEELNNQLFLYDTHQNLRGANRDALVKEFNVNENQLQLYQEKCNRRLREKRVSNSRFYS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24135-1", "uniprot_id": "PLCG2_RAT", "id": "P24135-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2", "aln": "-MTTMVNVDTLPEYEKSQIKRALELGTVMTVFSARKSTPERRTVQMIMETRQVAWSKTADKIEGFLDIMEIKEIRPGKNSKDFERAKA--VRHKADCCFTIFYGTQFVLSTLSLATDSKEDAVKWLSGLKILHQEAMNASTPTMIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVSGIKFLKDKLVEIGAQKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASAVYLQDFQRFLLHEQQELWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRAGCRCIELDCWDGPDGKPIIYHGWTRTTKIKFDDVVQAIRDHAFVTSSFPVILSIEEHCSVEQQRHMAKVFKEVLGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNVEDKKDEHKTQGELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTVEEDPVQDTPPTELHFGEKWFH-KKVESRTSAEKLLQEYCAETGAKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGVMKYYLTDNLTFNSIYALIQHYREAHLRCAEFELRLTDPVPNPNPHESKPWYYDRLSRGEAEDMLMRIPRDGAFLIRKREGTDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDYKAKRSDELTFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISAGDAEEMEKQIIEDNPLGSLCRGILDLNTYNVVKAPQGKNQKAFVFILEPKKQGDPPVEFATDRVEELFEWFQSIREITWKIDTKENNMKYWERNQSIAIELSDLVVYCKPTSKTKDHLENPDFREIRSFVETKADSIVRQKPVDLLRYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKYMQMNHALFSLNGRTGYVLQPESMRSEKYDPMPPESQRKILMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDSNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFLVYEEDMFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCRQLRRRQEELNNQLFLYDTHQNLRGANRDALVKEFNVNENQLRLYQEKCNRRLREKRVSNSRFYS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8C2MLP8-1", "uniprot_id": "A0A8C2MLP8_CRIGR", "id": "A0A8C2MLP8-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma", "aln": "-MTTMVNVDTLPEYEKSQIKRALELGMVMTVFSARKGTSERRTVQVIMETRQVAWSKTADKIEGFLDIMEIKEIRPGKNSKDFERAKATVSRHKADCCFTIFYGTQFVLSTLSLATDSKEDAMKWLSGLKILHQEAMSASTPTMIESWLRKQIYSVDQTRRNSISLRELKAILPLVNFKVSSVKFLKDKLVEIGAQKDELSFEQFHLFYKKLMFDQQKSILDEFKKDSSVFILGNTDRPDASAIHLQDFQRFLLHEQQELWAQDLNKVRERMTKFIDDTMRETAEPFLYVDEFLTYLFSRENSIWDEKYDTVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRAGCRCIELDCWDGPDGKPIIYHGWTRTTKIKFDDVVQAIRDHAFVTSSFPVILSIEEHCSVEQQRHMAKVFKEVLGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNVEDKKDEHKTQGELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQAVEEELVQDTTPTELHFGEKWFH-KKVERRTSAEKLLQEYCAETGAKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGVMKYYLTDNLTFNSIYALIQHYREAHLRCAEFELRLTDPVPNPNPHESKPWYYDRLSRGEAEDMLMRIPRDGAFLIRKREGTDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDYKAKRSDELTFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISAGDAEEMEKQIIEDNPLGSLCRGILDLNTYNVVKAPQGKNQKAFVFILEPKKQGDPPVEFATDRVEELFEWFQSIREITWKIDTKENNMKYWERNQSIAIELSDLVVYCKPTSKTKDHLENPDFREIRSFVETKADSIVRQKPIDLLRYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKYMQMNHALFSLNGRTGYVLQPESMRSEKYDPMPPESQRKILMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDSNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLECEEELYSSCRQLRRRQEELNNQLFLYDTHQNLRGANRDALVKEFNVNENQLQLYQEKCNRRLREKRVSNSRFYS", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "P16885-1", "uniprot_id": "PLCG2_HUMAN", "id": "P16885-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2", "aln": "-MSTTVNVDSLAEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADKIEGFLDIMEIKEIRPGKNSKDFERAKA--VRQKEDCCFTILYGTQFVLSTLSLAADSKEDAVNWLSGLKILHQEAMNASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLINFKVSSAKFLKDKFVEIGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASAVYLHDFQRFLIHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDCWDGPDGKPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCSVEQQRHMAKAFKEVFGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNMEDKKDEHKQQGELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTMEEEVPQDIPPTELHFGEKWFH-KKVEKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGSDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHSLYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDYKAKRSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISTADFEELEKQIIEDNPLGSLCRGILDLNTYNVVKAPQGKNQKSFVFILEPKQQGDPPVEFATDRVEELFEWFQSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVETKADSIIRQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKYMQMNHALFSLNGRTGYVLQPESMRTEKYDPMPPESQRKILMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDNNKFKTTVVNDNGLSPIWAPTQEKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKAVKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCRQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFSVNENQLQLYQEKCNKRLREKRVSNSKFYS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1S475-1", "uniprot_id": "F1S475_PIG", "id": "F1S475-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma", "aln": "-MSAMISVDALPEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADKIEGFLDIMEIKEIRPGKNSKDFERAKA--VRQKEDCCFTIFYGTQFVLSTLSLAADSKEDAMKWLSGLKILHQEVMSASTPTVIESWLRKQIYSVDQTRRNSISLRELKAILPLVNFKASSAKFLKDKFLEIGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASAVHLHDFQRFLLHEQQELWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDVVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRMGCRCIELDCWDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCCVEQQRHMARVFKEVFGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNMEDKKDEHKQQGELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTVEEEPPVNTPPTELHFGEKWFH-KKVEKRTSAEKLLQEYCAETGGKDGTFLVRESETYPNDYTLSFWRSGRVQHCRIRSTMEGGVMKYYLTDNLMFTSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWYYDGLSRGEAEDMLMRVPRDGAFLIRRREGTDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDYRAKQSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISAVDVEELEKQIIEDNPLGSLCRGILDLNTYNVVKAPQGKNQKPFVFILEPKKQGDPPVEFATDRVEELFEWFQSIREITWKIDTKENNMRYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVETKADSVTRQKPNDLLKYNQKALTRIYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKYMQMNHALFSLNGRTGYVLQPESMRAEKYDPMPPESQRKILMTLTVKVLGARHLPKTGRSIVCPFVEVEICGAEYDNNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFVVYEEDIFSDPNFLAHATYPIKGIKSGYRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYASCRQLRRRQEELNNQLFLYDTHQNLRNANRDALVREFNVNENQLQLYQEKCNRRLREKRVSNSKFYS", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A1D5PHP4-1", "uniprot_id": "A0A1D5PHP4_CHICK", "id": "A0A1D5PHP4-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma", "aln": "MPRKSVDYGELPEYEKSQIKRTLELGTVMTVFSIKKSSLERRTIQVIMETRQVAWSKTADKIEGFLDLMEIKEIRPGKNSKDFERCKA---KHREEHCFTIFYGTQFVLNTLSLAADSKGDADKWLCGLNILYQEVMRAPTPAITESWLRKQIYSVDQTRRNSISLRELKAVLPQVNFKVSSMKFLKDKFAEIGAHKEELSFEQFHLFYKKIMFEQQKSILDEFKKDSSVFILGNTDRPDASAVHLHDFQRFLLHEQQESWAQDLSKVRERMTEFVDDTMRETAEPFLFVDEFLTYLFAKENSIWDEKYDTIDVQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRMGCRCIELDCWDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSEYPVILSIEEHCSVEQQRHMAKVFKEVFGDQLLMKPVEASADQLPSPTQLKEKIIIKHKKLGPKGDIDVNLEDKKEEKKQQGELYMWDAIEQQWTRHYCAIADGKLSFSDVIEQNADEDSSKEVKRTELHLKEKWFHGKMKEGRTTAEKLLQEYCAEMGGKDGTFLVRESEAFPNDCTLSFWRSGRVQHCRIRSSSDGDTVKYYLTDNVTFDSIYDLIQHYKEVHLRCAEFDLRLTDAVPNPSPHENKDWYYSNLSRGEAEDMLMRIPRDGAFLIRKRDEPDSFAMTFRAEGKVKHFRIQQEGRHFVLGTSAYFESLVELVTYYEKHPLYRKMKLRYPVTEELLERYSTEKDINSLYDVK-MYVEPSEITPTVPQRTVKALYDYRAKRSDELSFSRGALIHNVTKETGGWWKGDYGEKVQHYFPSNYVEDLSSDNSAELESQIIEDNPLGSLCHGILVLNTYNVVKMPQGKHKKPFVFILEPKNPEDPCVEFATDKVEELFEWYQSVREITWKTAEEENRRKYWEKNQLIAIELSDLVIYCKPTSKTKDNLENPDFKEIRSFVETKAESIVKQKPVELLKYNLKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKYMQLNHALFSLNGHTGYVLQPESMRNEEYDPMPNESKRKLQMIMTVRVLGARHLPKLGRSIACPFVEVEICGAEYDNNKFKTTVVNDNGLNPVWAPCPEQVKFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATFPIKGIKSGFRSVPLKNGYSEDIELASLLIHCEMQQVLEYEEELYSSCRQLRKRQEELNNQLFLYDTHMNLRNPNRDALLREFNVNEHKLQMCQETCNRRLREKKVSNSKFYS", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q1LWV7-1", "uniprot_id": "MEAK7_DANRE", "id": "Q1LWV7-1", "name": "MTOR-associated protein MEAK7", "aln": "----------------------------------------------------------MGNGDSVVAQKRLARFRPDE-------------RPAVEGTFDRLHG--------ARSSASAGKTSKGLS-LDMLQLTMGKMASESMIKRVFQG-----------------LHSIDPGVPLHPG----------------DGVSREQLLIFLADVLRG--------TAEERAPLVLAMAEG-----------------------AKATVTTTEQIRGFMEDLVYAAVQTLAHKGHLRAWHPERMG------------------------DGAQGVKLLAEQLTSELKPSDQNSCD------------------------------------IACLEDWLFRIP------------------MMAMFLELLIGEGLGVVLPSRPPPTLLPPCQFAP-----------------------------------------WTDLRCVLSLPLLMFLSPLLPEGHSAPWRMLFSTKMHG-ESFTR-------------LLGSCKSRGP--TVLLVKDTKGY-------IFGGFSSQSWEVKPQFQG-------------------------------------------------------------------------------------------------------DSRCFLFSVFPYMR--VFTCTGYNDHYMYLNQ--------------------------------------------------------GQQTMPNGLGMGGQHGYFGLWLDYDFGHGHSRARPR--CTTYGSPQLSADEDFKLDT------------LEVWGVGKLPEEQEE-----------------------------------------DEKKKSILDADLEVQAMMEMTGKTLHSQGLREPEEDED-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :..: .: .:**.: : : * ::* : :: * .: : *. *.:* .: :: : :: *::: * : :: . : :* **: :* .:: :: : ::*. :: *: .. *:: *::* : :.:.: . ..: :: : . ..::.. * .:** ** ... * : .:.* * . ** :: ::*: * . .. * .* *: ** *.:: * * . : .. *::* *.: : * * . * .:**:::: : :: . * .::. :. :.* *::.. .*:. * : *:.* :* : .: :: .* : . * * . *:* .: * .: : *. :: *:.:.* * *: :.: ::: : : :*::. .::.: :.::. : ", "identical_positions": 67, "similar_positions": 189, "identity": "5.28%" }, { "cls_id": "homologset.oma.817203", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K3X8-1", "uniprot_id": "HSBP1_RAT", "id": "Q8K3X8-1", "name": "Heat shock factor-binding protein 1", "aln": "------------------MAETDPKTMQDITLVVETLLQQMQDKFQIMSDQIIGRIDDMSSRIDDLEKNIADLMTQAGVEELDA-------ENKIPTA-QKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQZ1-1", "uniprot_id": "HSBP1_MOUSE", "id": "Q9CQZ1-1", "name": "Heat shock factor-binding protein 1", "aln": "------------------MAETDPKTMQDITLVVETLLQQMQDKFQIMSDQIIGRIDDMSSRIDDLEKNIADLMTQAGVEELDP-------ENKIPTA-QKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75506-1", "uniprot_id": "HSBP1_HUMAN", "id": "O75506-1", "name": "Heat shock factor-binding protein 1", "aln": "------------------MAETDPKTVQDLTSVVQTLLQQMQDKFQTMSDQIIGRIDDMSSRIDDLEKNIADLMTQAGVEELES-------ENKIPAT-QKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3ZC22-1", "uniprot_id": "HSBP1_BOVIN", "id": "Q3ZC22-1", "name": "Heat shock factor-binding protein 1", "aln": "------------------MAETDPKTVQDLTSVVQTLLQQMQDKFQTMSDQIIGRIDDMSSRIDDLEKNIADLMTQAGVEELDS-------ENKIPAT-QKS", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A287BMT8-1", "uniprot_id": "A0A287BMT8_PIG", "id": "A0A287BMT8-1", "name": "Heat shock factor-binding protein 1", "aln": "------------------MAETDPKTVQDLTSVVQTLLQQMQDKFQTMSDQIIGRIDDMSSRIDDLEKNIADLMTQAGVEELEG-------DNKIPAT-QKS", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A1D5PAM4-1", "uniprot_id": "A0A1D5PAM4_CHICK", "id": "A0A1D5PAM4-1", "name": "Heat shock factor-binding protein 1", "aln": "------------------MAETDPKTVQDLTAVVQTLLQQMQDKFQTMSDQIIGRIDDMSCRIDDLEKNIADLMTQAGVEELEG-------ENKAPATTNKS", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9VK90-1", "uniprot_id": "Q9VK90_DROME", "id": "Q9VK90-1", "name": "Heat shock factor-binding protein 1", "aln": "MTDLRNEMDSDLDQNYSLNSNADPKNMQELTIYVQNLLQNVQDKFQTMSDQIITRIDDMGNRIDDLEKSIADLMNQAGIEGQGP-------EK---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8GW48-1", "uniprot_id": "HSBP_ARATH", "id": "Q8GW48-1", "name": "Heat shock factor-binding protein", "aln": "-------MDG-------HDSEDTKQSTADMTAFVQNLLQQMQTRFQTMSDSIITKIDDMGGRINELEQSINDLRAEMGVEGTPPPASKSGDEPKTPAS--SS", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :. ::* *:.***::* :** ***.** :****. **::**:.* ** : *:* : ", "identical_positions": 26, "similar_positions": 21, "identity": "25.49%" }, { "cls_id": "homologset.oma.817204", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9E1-1", "uniprot_id": "HSBPL_RAT", "id": "D4A9E1-1", "name": "Heat shock factor-binding protein 1-like protein 1", "aln": "MDARTPEVPCGDLLQNAAENLLQEVEEHFQALTATLNLRMEEMGNRIEDLQRNVDDLMAQAGIENSIKEATT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RXB2-1", "uniprot_id": "HSBPL_MOUSE", "id": "B2RXB2-1", "name": "Heat shock factor-binding protein 1-like protein 1", "aln": "MDTRTPEVPCGDLLQNAAENLLLEVEEHFQALTTTLNLRMEEMGSRIEDLQRNVDDLMTQAGIENSIKEPAT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C9JCN9-1", "uniprot_id": "HSBPL_HUMAN", "id": "C9JCN9-1", "name": "Heat shock factor-binding protein 1-like protein 1", "aln": "MDVRGPEAPGGRALRDAAENLFQELQEHFQALTATLNLRMEEMGNRIEDLQKNVKDLMVQAGIENSIKEQMLKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1D5PHZ3-1", "uniprot_id": "A0A1D5PHZ3_CHICK", "id": "A0A1D5PHZ3-1", "name": "", "aln": "MAAGEP--LGAECLSQLAENLLHQLQENFQALTERITLRMEEMGERINDLEKHVADLMAEAGIENTDDGLRH--", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . * . * : ****: :::*:***** :.*******.**:**:::* ***.:*****: . ", "identical_positions": 33, "similar_positions": 19, "identity": "44.59%" }, { "cls_id": "homologset.oma.817267", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYU1-1", "uniprot_id": "PEX19_RAT", "id": "Q9QYU1-1", "name": "Peroxisomal biogenesis factor 19", "aln": "MAAAEGGCGAGVEADRELEELLESALDDFDKAKP------------SPAPSPTISAPDASGPQKRSPGDTAK--DALFASQEKFFQELFDSELASQ--ATAEFEKAMKELAEEEPHLVEQFQKLSEAAGRVGSDASSQ-----QEFTSCLKETLSGLAKNATDLQNSGMSEEE--------------LTKAMEGLGMD-EGDGEG-NILPIMQS--------LMQNLLSKDVLYPSLKEITEKYPEWLQSH-QESIPPEQFEKYQQQHSVMGKICEQFEAETPTDSEATHRARFEAVLDLMQQLQDLGHPPKELAGEMPPG-------LNFDLDALNLSGPPGANGEQCLIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60415-1", "uniprot_id": "PEX19_CRIGR", "id": "Q60415-1", "name": "Peroxisomal biogenesis factor 19", "aln": "MAAAEEGCDAGVEADRELEELLESALDDFDKAKP------------SPAPPPTTSAPDASGPQKKSPGDTAK--DALFASQEKFFQELFDSELASQ--ATAEFEKAMKELAEEEPHLVEQFQKLSEAAGRVGSDANSQ-----QEFTSCLKETLSGLAKNATDLQNSGMSEEE--------------LTKAMEGLGMD-DGDGDG-NILPIMQS--------IMQNLLSKDVLYPSLKEITEKYPEWLQSH-QESIPPEQFEKYQEQHSVMGKICEQFEAETPTDSEATHRARFEAVLDLMQQLQDLGHPPKELAGEMPPG-------LNFDLDTLNLSGPPGANGEQCLIM", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "P40855-1", "uniprot_id": "PEX19_HUMAN", "id": "P40855-1", "name": "Peroxisomal biogenesis factor 19", "aln": "MAAAEEGCSVGAEADRELEELLESALDDFDKAKP------------SPAPPSTTTAPDASGPQKRSPGDTAK--DALFASQEKFFQELFDSELASQ--ATAEFEKAMKELAEEEPHLVEQFQKLSEAAGRVGSDMTSQ-----QEFTSCLKETLSGLAKNATDLQNSSMSEEE--------------LTKAMEGLGMD-EGDGEG-NILPIMQS--------IMQNLLSKDVLYPSLKEITEKYPEWLQSH-RESLPPEQFEKYQEQHSVMCKICEQFEAETPTDSETTQKARFEMVLDLMQQLQDLGHPPKELAGEMPPG-------LNFDLDALNLSGPPGASGEQCLIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3SZD1-1", "uniprot_id": "PEX19_BOVIN", "id": "Q3SZD1-1", "name": "Peroxisomal biogenesis factor 19", "aln": "MAAAEGDGGVRAEADRELEELLESALDDFDKAKP------------SPAPPPTTTAPDASGPQKRSPGDTAK--DALFASQEKFFQELFDSELASQ--ATAEFEKAMKELAEEEPHLVEQFQKLSEAAGRVGSDATSQ-----QEFTSCLKETLSGLAKNATDLQNSGMSEEE--------------LTKAMEGLGMD-EGDGEG-TILPIMQS--------IMQNLLSRDVLYPSLKEITEKYPEWLRAH-RDSLPPEQFEKYQEQHSVMGKICEQFEAETPTDSEATQKARFEVVLDLMQQLQDLGHPPKELAGEMPPG-------LNFDLDALNLSGPPGANGEQCLIM", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q8VCI5-1", "uniprot_id": "PEX19_MOUSE", "id": "Q8VCI5-1", "name": "Peroxisomal biogenesis factor 19", "aln": "MAAAEEGCGVGVEDDRELEELLESALDDFDKAKP------------SPEHAPTISAPDASGPQKRAPGDTAK--DALFASQEKFFQELFDSELASQ--ATAEFEKAMKELAEEEPHLVEQFQKLSEAAGRVGSDASSQ-----QEFTSCLKETLSGLAKNATELQNSGMSEEE--------------LMKAMEGLGMD-EGDGEA-SILPIMQS--------IMQNLLSKDVLYPSLKEITEKYPEWLQSH-QDSTPPEQFEKYQQQHSVMVKICEQFEAETPTDSEATQRARFEAMLDLMQQLQALGHPPKELAGEMPPG-------LNFDLDALNLSGPPGANGEQCLIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IP97-1", "uniprot_id": "Q8IP97_DROME", "id": "Q8IP97-1", "name": "Peroxin-19", "aln": "-------MSEEKKNGDELNDLLDSALQDFDKSGA------------GDQKEPSASSDVATN--AGPEGSEDP--DAFFIEQAKVLADRMNTLFGGP--DTPSGD--IPPLPQDPDQIMAGFKKMAEAAALTLSGENSATDEDVSKYSDSISQALKGLQEGSENLAAP-ASEND--------------IASMFGSLNLEGAGEGDGNMFLPFMEG--------MMQSLLSAEILLPSIRELLEKYPKYLEEN-DAKLSAEDKERYQKQMELYKVIEGHLQSEKTEDSAAVKREKFRVVLDDMRKLQDYGQPPPEILAETGGD-------LPFGDPTAGVAA--GGPGPQCPTM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07418-1", "uniprot_id": "PEX19_YEAST", "id": "Q07418-1", "name": "Peroxisomal membrane protein import receptor PEX19", "aln": "------MNENEYDNFDDLDDLLDEDPTKLDEAEPDDVQAKGSVYNDSENKEKNAESKDSDGVQVANESEEDPELKEMMVDLQNEFANLMKNNGNENNVKTEDFNKLISALEEAAKVPHQQMEQGCSSLKSNSTDKGTVNGSN-PGFKNIVSNTLDRLKENGNKVDTSLAEETKESQRSGQNNNIDDILSQLLDQMVAS-GGKESAENQFDLKDGEMDDAITKILDQMTSKEVLYEPMKEMRSEFGVWFQENGENEEHKEKIGTYKRQFNIVDEIVNIYELK--DYDELKHKDRVTELLDELEQLGDSPIRSANSPLKHGNEEEELMKMLEIDGNDPNLGNLDKELTDGCKQQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*::**:. .:*:: . . . : : . .. . :: . : : : :.. * . : : * : ::: ..: :. : :.. :.::*. * :.. .: . .* . : . : : . *. .. : : :. :::.: * ::* .::*: .:: ::. : . *. *:.* .: * : : . :: :. :** :.:* . : : * :. .:. * ", "identical_positions": 22, "similar_positions": 112, "identity": "6.25%" }, { "cls_id": "homologset.oma.817311", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A140UHX3-1", "uniprot_id": "A0A140UHX3_RAT", "id": "A0A140UHX3-1", "name": "Condensin-2 complex subunit D3", "aln": "MVGMALKDLGRDLQPWCPLDLSLEWVNTVWDLDFTETEPLDPSVVAEILETGRDAFTKLYGSLFPFATDESGSLESVWSFFTENSISSNTLVALFCHFVQEAHKKSASVQYREYGLRAAGLYFLLLEIPGSVVNQVFHPVMFDKCIQILKKSWPQESNLTQKRKKEHSKSSKANYRRSRKRGKPPRKEDYQVDELSREEEEEEEEEIYFSVRDLSQIRDAIFNLLKNFLRLLPKFSLKEKPQSIQTCIEVFVALTSFEPIPHKFLISQARNLSEVKHISELAYYGLYLLCSPVHGEGNKVIGSIFHQMLNVILMLEVGEGSRCAPLAITSHVINCRNQAVQFVSSLVDELQESVFPILGTLLQHICAKVVDKAEYRTYAAQSLVQLLSKLPSKEYATFIAWLYKYSRSSKIPHRVFTLDVALALLELPERLLDDTVLLEHQKFLKHKFFVQEIIFDRCLDKAPTVRSKALSSFAQCLELSTSNTSENTLEIFINS-TVTGIHSHFGTSLRPSTVLTSQSCRSVQS------STHDSDEQTPPGERRFMTMLRKRTKDEKINVRKSALQVLMSILKHCDILSMEEDLLILQDHCRDPAISVRKQALQSLTELVMAKPTCVPVQKAWLMGVIPVVMDYESTVQEKALECLDQLLLQNIKHHRKFHSEDRSQVLAWALLALLTVESQDLSRYLNKAFHIWSKKDKFSSTFINSVISHTDTERSAPAWMLLSKITCSSPKLDYTKIMESWEKLSREQSPNSNTLGYMLCVIGHIAKHLPKSTQDKITGVIKAKLNGFQWSLELISLSVDTLQGLCRASAKTLREEQELLKRVCGDVLSTCEQHLSNILLKEDGTGNMDEDLVVKCIFTLGDIAQLCPALVEKRVFLLIQSILASSAHADHLPSSQGTTD-LASQLPFQARSSALPSVIRAHAIITLGKLCLQHEDLAKKSIPALVRELEVCEDVAVRNNVIIVMCDLCIRYTVMVDNYIPNISICLKDSDPFIRKQTLILLTNLLQEEYVKWKGSLFFRFVSTLVDSHPDIASLGEFCLAHLLLKRNPTMFFQHFIECIFHFNSYEKHGQYNKFSQSERGKPLFLLKGKTNKEKRMRIYKFLLEHFTDEQRFNVTSKICLNILACFTDGVLPVDMEASELLSDTFDILSSKEIKLLAMRAQASKELLEE-DDVALANVVMQEAQMKIISQVQKRNFIENIIPIIISLKTVLEKNKIPALRELMNYLREVMQDYRDEIKDFFAVDRQLASELEYDMKKYTEQLAQEQALTEHANATNVPADGDRVPSQQVAPDLQAVPGAAAA-------------AGAGQADANMPLPLAQSQPSAPGS--SFTPTLPPICEKGPLK-IMSSTRPMSLSTIAILNSVKKAVASKS--RTRSLGALSFNMENGSPENPSSRASSLSLEQESERAVKRVTKRAISTPEKSISNVTFGAGVSYIGTPATSFFTKEKPEEAQEEGNDILCLSLLDKRPPQSPQWNVKSPARSQDNPRSGRRSLRKAPLKTAN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZQK0-1", "uniprot_id": "CNDD3_MOUSE", "id": "Q6ZQK0-1", "name": "Condensin-2 complex subunit D3", "aln": "---MALQDLGENLQPWCPLGLSLEWVKTVWDLDFTEIEPLDPSIVGEILETGRDAFTKLYGSLFPFATDESGSLESIWTFFTENDISSNTLVALFCHFVQEAHKKSASAQYREYGLHAAGLYFLLLEIPGIVVNQVFHPVMFDKCIQILKRSWPQESNLTQKRKKDHSKSSKDNYRKSRKRGKPPRKEDYQVDELSREEEEEEEE-IYFSGRDLCQIRDAIFNLLKNFLRLLPKFSLKEKPQSIQTCIEVFVALTSFEPIPHKFLISQARNLNEVKHISELAYYGLYLLCSPVHGEENKVIGSIFHQMLNVILMLEVGEGSRCAPLAITSQVINCRNQAVQFVSSLVDELQASVYPVLGTLLQHICAKVVDKAEYRTYAAQSLVQLLTKLPSEEYATFIAWLYKYSRSSKIPHRVFTLDVALALLTLPERELDDTVSLEHQKFLKHKFFVQEIIFDRCLDKAPTVRSKALSSFAHCLELSSSNTSESILEIFINSNLVPGIQNLSNTVLNPSPVLTSRNGYSAQS------RTHNNDEQTLPGERCFMTMLRKRIKDEKINVRKSALQVLMSILKHCDILSMEQDLLILQDHCRDPAISVRKQALQSLTELVMAQPTCVPVQKAWLMGVIPVVMDCESTVQEKALECLDQLLLQNIKHHKKFHSADRSQVLAWSLLALLTIENQDLRRYLNKAFHIWSKKDKFSSTFINSVISHTDTERSAPAWMLLSKITCSSPKLDYTKIIESWERLSREQSPNSNTLGYMLCVIGHIAKHLPKGTRDKITGVIKAKLNGFQWSPELISSSVDALQKLCRASAKTVLEEQGLLKQVCGDVLATCEQHLSNILLKEDGTGNMDEGLVVKCIFTLGDIAQLCPAIVEKRVFLLIQSILASSAHSDHLPSSQGTTDALDSQPPFQPRSSAMPSVIRAHAIITLGKLCLQHEDLAKKSIPALVRELEVSEDVAVRNNVIIVICDLCIRYTVMVDNYIPNISVCLKDSDPFIRKQTLVLLTNLLQEEYVKWKGSLFFRFVSTLVDSHPDIASLGEFCLAHLLLKRNPTMFFQHFIECIFHFNSYEKHGQYNKFSQSERGKQLFLLKGKTNKEKRMRIYKFLLEHFTDEQRFNVTSKICLNILACFTDGILPMDMEASELLSDTFDILNSKEIKLLAMRAQTSKDLLEE-DDVALANVVMQEAQMKIISQVQKRNFIENIIPIIISLKTVLEKNKIPALRELMNYLREVMQDYRDEINDFFAVDKQLASELEYDMKKYNEQLAQEQALTEHANATKGPEDSDRVPSAQVAPDLEAVPALAAAPMAAAAAAAPMAAAAAAAGQDNADVPPTQSRPSAPRS--NFTPTLPPISENGPLK-IMSSTRPMSLSTIAILNSVKKAVASKN--RTRSLGALPFNVETGSPENPSSHESSLSLEKESDRTVNHVTKRAISTPENSISDVTFAAGVSYIGTPAT-FFTKEK-HEAQEQGSDILCLSLLDKRPPQSPQWNVKSPARSHGSTRSSRRSLRKAPLKTAN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42695-1", "uniprot_id": "CNDD3_HUMAN", "id": "P42695-1", "name": "Condensin-2 complex subunit D3", "aln": "--MVALRGLGSGLQPWCPLDLRLEWVDTVWELDFTETEPLDPSIEAEIIETGLAAFTKLYESLLPFATGEHGSMESIWTFFIENNVSHSTLVALFYHFVQIVHKKNVSVQYREYGLHAAGLYFLLLEVPGSVANQVFHPVMFDKCIQTLKKSWPQESNLNRKRKKEQPKSSQANPGRHRKRGKPPRREDIEMDEIIEEQE---DENICFSARDLSQIRNAIFHLLKNFLRLLPKFSLKEKPQCVQNCIEVFVSLTNFEPVLHECHVTQARALNQAKYIPELAYYGLYLLCSPIHGEGDKVISCVFHQMLSVILMLEVGEGSHRAPLAVTSQVINCRNQAVQFISALVDELKESIFPVVRILLQHICAKVVDKSEYRTFAAQSLVQLLSKLPCGEYAMFIAWLYKYSRSSKIPHRVFTLDVVLALLELPEREVDNTLSLEHQKFLKHKFLVQEIMFDRCLDKAPTVRSKALSSFAHCLELTVTSASESILELLINSPTFSVIESHPGTLLRNSSAFSYQRQTSNRSEPSGEINIDSSGETVGSGERCVMAMLRRRIRDEKTNVRKSALQVLVSILKHCDVSGMKEDLWILQDQCRDPAVSVRKQALQSLTELLMAQPRCVQIQKAWLRGVVPVVMDCESTVQEKALEFLDQLLLQNIRHHSHFHSGDDSQVLAWALLTLLTTESQELSRYLNKAFHIWSKKEKFSPTFINNVISHTGTEHSAPAWMLLSKIAGSSPRLDYSRIIQSWEKISSQQNPNSNTLGHILCVIGHIAKHLPKSTRDKVTDAVKCKLNGFQWSLEVISSAVDALQRLCRASAETPAEEQELLTQVCGDVLSTCEHRLSNIVLKENGTGNMDEDLLVKYIFTLGDIAQLCPARVEKRIFLLIQSVLASSADADHSPSSQGSSEAPASQPPPQVRGSVMPSVIRAHAIITLGKLCLQHEDLAKKSIPALVRELEVCEDVAVRNNVIIVMCDLCIRYTIMVDKYIPNISMCLKDSDPFIRKQTLILLTNLLQEEFVKWKGSLFFRFVSTLIDSHPDIASFGEFCLAHLLLKRNPVMFFQHFIECIFHFNNYEKHEKYNKFPQSEREKRLFSLKGKSNKERRMKIYKFLLEHFTDEQRFNITSKICLSILACFADGILPLDLDASELLSDTFEVLSSKEIKLLAMRSKPDKDLLMEEDDMALANVVMQEAQKKLISQVQKRNFIENIIPIIISLKTVLEKNKIPALRELMHYLREVMQDYRDELKDFFAVDKQLASELEYDMKKYQEQLVQEQELAKHADVAGTAGGAEVAPVAQVALCLETVP--------------------VPAGQENPAMSPAVSQPCTPRASAGHVAVSSPTPETGPLQRLLPKARPMSLSTIAILNSVKKAVESKSRHRSRSLGVLPFTLNSGSPEKTCSQVSSYSLEQESNGEIEHVTKRAISTPEKSISDVTFGAGVSYIGTPRTPSSAKEK-IEGRSQGNDILCLSLPDKPPPQPQQWNVRSPARNKDTPACSRRSLRKTPLKTAN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**:.** .*******.* ****.***:***** ******: .**:*** ****** **:****.* **:**:*:** **.:* .****** **** .***..*.*******:**********:** *.************** **:********.:****::.***: * : ********:** ::**: .*:* :* * ** ***.***:***:*******************.:*.******:**.***: *: ::*** *.:.*:*.*************:*** :***..:*****.***********: ****:**:***********:*:*****: *::*:: ************:****:*********:***. *** ***********************.**** **** :*:*: ***********:****:********************:****: :.:**. **::*** .. *.. .* *. *..:: : * :* ....* . .*** .*:***:* :*** **********:*******: .*::** ****:*****:*************:**:* ** :***** **:***** ********** *********:** :*** * ******:**:*** *.*:* *************:***.****.*****.**:***********: ***:***::*::***::* :*.*******::*************.*:**:*..:*.******** *:** :**:** ******:* *** **.:******:***::****:***:*******.*:** ************* ****:******:*****.:** *****::: ** * * *.*.:************************************.************:********:***:******:**************:*********:***************:********:**************.**************.**** :****.**** * ** ****:***:**:****************:******.*****:**:**:*::*********::*.**********::..*:** * **:*********** *:************************************:************::******:************* ***.*** *::**:.: . ..: .* *** *::** . .: * :. : *:*.:* : ..... .* *.***: ::..:****************** **. *:****.*.*.::.****:..*: ** ***:**: :::**********:***:***.********* * :*** *.:.:*.******* ** ***. ****:****.:... ..******:******", "identical_positions": 1071, "similar_positions": 286, "identity": "70.28%" }, { "cls_id": "homologset.oma.817331", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "M0R3M8-1", "uniprot_id": "M0R3M8_RAT", "id": "M0R3M8-1", "name": "", "aln": "MGRSGKLPSGVSAKLKRWKKGHSSDSNPTTCRHRQAARSRFFSR-----PSGKSDLTVDAVKLHNELQ------------SGTLSLGKSQAPETTMDQDPEVAFTEKSSG------TFLSGLSDCTNVTFSKVQRFWESNSAAHKEICAVLAAVTEVIRSQGGKETETEYFAALMTTMEAVESPES-----------LAAVAYLLNLVLKRVPSPVLMKKFSDTSKAFMNIMSAQASSGS----------TSALRWVLSCLAILLRKQD---LEAWG-----YPITLQVYHGLLSFTVHAK-PKVRKAAQHGVCSVLKGSDFMFGEEAPA--------------HHPAAVSTAKFCIQEIEKSGGSREATTTLHMLTLLKDMLPCFPEGLVKSCSETLLRVMTLNHVLVTACAMQAFHNLFHAKPSP---STLSAELNAQIITALYDYVPSENDLQPLLAWLKVMEKAHINLVRLQRDLGLGHLARFFGIAVT-CLLSPHSQVVAAATQTLKEILRECV-----APHVADIG-SVTSSASGPPQYIAKMFRAVEEGLTYRFHAAWSSVLQLLGVFFEACGKQAHPVMKKCLQSLCDLRLSPHFPHTAA--LDQAVGAAVTSMGPEVVLQAVPLEID-GSEETLDFPRSWLLPVIRDHVRETRLGFFTTYFLPLATALKRKAMDLAQAGSAVESKIYDTLQWQIWTLLPGFCIRPTDVAASFKGLAR-TLGTAISERPDLRVTVCQALRTLITKGCEAEADR-----------------------AEVSRFAKNFLPILFNLYGQPVAAGEAEAPRRAVLETIKTYLTITESQLVNGFLEKATEKVLDPASSD--------------------------FTRLSVLDLVVALAPYSDEAAISKLYSTIRP------------YLESKVHGVQKKAYRVLEEVCASSQGPAARFVQSHLDDLKKTLLDSLQSTSSPAKRPRLKCLIHIVKKLS------------------------------------------------------------AEHEEFIAALIPEVILCTKEVSVGARKNAFTLLVEMGHAFLRFDSSQE-----------------EALQRYLVLIYPGLLG-AVTTVSCSILALTHLLFEFKGLMGTSTVEQLLENVCLLLASRTRDVVKSALGFIKVAVVVMD-VVHLAKHVQLVLEAIGKLSDDMRRHFRMKLRNLFIKFIRKFGSVFELVKDLLPAEYHKVLVNIRKAETRAKKHRALSQA-----AMEEEEE-EEEEK-PVQSKGDSIEEILADS-----EDED--EEEERSQGKE-------------QRKLARQRSRAWLKEGGGDEPLNFLDPKVAHRVLAT-----------QPGPGRGKKKDHGFKLSADGRLIIREEEDGDKVEEEDVT-----------KGEDEEMTDVMEDASVRSKK--KLKRQREDEE----------------------DELEIPPRYQAGGSGIHRPVAK-------------------KAAPGAEYKAKKAKGDVKRKGRLDPYAYVPLNRTKLNRRKK------------VKLQGQFKGLVKAAQRGSQVGHKLHRKDRRP--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P5B0-1", "uniprot_id": "RRP12_MOUSE", "id": "Q6P5B0-1", "name": "RRP12-like protein", "aln": "MGRSGKLPSGVSAKLKRWKKGHSSDSNPATCRHRQAARSRFFSR-----PSGKSDLTVDAVKLHNELQ------------SGTLSLGKSQAPETTMDQDPEVAFTEKSSG------TFLSGLSDCTNVTFSKVQRFWESNSAAHKEICAVLAAVTEVIRSQGGKETETEYFAALMTTMEAVESPES-----------LAAVAYLLNLVLKRVPSPVLMKKFSDTSKAFMDIMSAQASSGS----------TSALRWVLSCLAILLRKQD---LEAWG-----YPITLQVYHGLLSFTVHAK-PKIRKAAQHGVCSVLKGSDFMFGEKAPA--------------HHPAAVSTAKFCIQEIEKSGGSKEATTTLHMLTLLKDMLPCFPEGLVKSCSETLLRVMTLNHVLVTACAMQAFHNLFHAKPSP---STLSAELNAQIVTALYDYVPSENDLQPLLAWLKVMEKAHINLVRLQRDLGLGHLARFFGTAVT-CLLSPHSQVAAAATQTLKEILKECV-----APHIADIG-SVTSSASGPPQYITKMFRAVEEGLTYKFHAAWSSVLQLLGVFFEACGKQAHPVMKKCLQSLCDLRLSPHFPHTAA--LDQAVGAAVTSMGPEVVLQAVPLEID-GSEETLDFPRSWLLPVIRDHVRETRLGFFTTYFLPLATTLKRKAMDLAQAGSTVESKIYDTLQWQIWTLLPGFCTRPTDVAASFKGLAR-TLGTAINERPDLRVTVCQALRTLITKGCEAEADR-----------------------AEVSRFAKNFLPILFNLYGQPVAAGEAAAPRRAVLETIKTYLTITEAQLVNSFLEKATEKVLDPASSD--------------------------FTRLSVLDLVVALAPYSDEAAISKLYSTIRP------------YLESKVHGVQKKAYRVLEEVCASSQGPAARFVQSHLDDLKKTLLDSLRTTSSPAKRPRLKCLIHIVKTLS------------------------------------------------------------AEHEEFIAALIPEVILCTKEVSVGARKSAFTLLVEMGHAFLRFGSNQE-----------------DALQRYLVLIYPGLLG-AVTTVSCSILALTHLLFEFKGLMGTSTVEQLLENVCLLLASRTRDVVKSALGFIKVAVVVMD-VVHLAKHVQLVMEAIGKLSDDMRRHFRMKLRNLFIKFTRKFG--FELVKGLLPAEYHKVLINIRKAETRAKKHRALSQA-----AVEEEEE-EEEEEEPVQSKGDSIEEILADS-----EDED--EEEERGRGKE-------------QRKLARQRSRAWLKEGGGDEPLNFLDPKVAHRVLAT-----------QPGPGRGKKRDHGFKLSADGRLIIREEEDGNKVEEEDGT-----------KGEDEDMTDAMEDASVRSKK--KLKRQREDEE----------------------DELEIPPRYQAGGSGIHRPVAK-------------------KAAPGAEYKAKKAKGDVKKKGRLDPYAYVPLNRSKLNRRKK------------VKLQGQFKGLVKATQRGSQAGHKLRRKDRRRP-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JTH9-1", "uniprot_id": "RRP12_HUMAN", "id": "Q5JTH9-1", "name": "RRP12-like protein", "aln": "MGRSGKLPSGVSAKLKRWKKGHSSDSNPAICRHRQAARSRFFSR-----PSGRSDLTVDAVKLHNELQ------------SGSLRLGKSEAPETPMEEEAELVLTEKSSG------TFLSGLSDCTNVTFSKVQRFWESNSAAHKEICAVLAAVTEVIRSQGGKETETEYFAALMTTMEAVESPES-----------LAAVAYLLNLVLKRVPSPVLIKKFSDTSKAFMDIMSAQASSGS----------TSVLRWVLSCLATLLRKQD---LEAWG-----YPVTLQVYHGLLSFTVHPK-PKIRKAAQHGVCSVLKGSEFMF-EKAPA--------------HHPAAISTAKFCIQEIEKSGGSKEATTTLHMLTLLKDLLPCFPEGLVKSCSETLLRVMTLSHVLVTACAMQAFHSLFHARPGL---STLSAELNAQIITALYDYVPSENDLQPLLAWLKVMEKAHINLVRLQWDLGLGHLPRFFGTAVT-CLLSPHSQVLTAATQSLKEILKECV-----APHMADIG-SVTSSASGPAQSVAKMFRAVEEGLTYKFHAAWSSVLQLLCVFFEACGRQAHPVMRKCLQSLCDLRLSPHFPHTAA--LDQAVGAAVTSMGPEVVLQAVPLEID-GSEETLDFPRSWLLPVIRDHVQETRLGFFTTYFLPLANTLKSKAMDLAQAGSTVESKIYDTLQWQMWTLLPGFCTRPTDVAISFKGLAR-TLGMAISERPDLRVTVCQALRTLITKGCQAEADR-----------------------AEVSRFAKNFLPILFNLYGQPVAAGDTPAPRRAVLETIRTYLTITDTQLVNSLLEKASEKVLDPASSD--------------------------FTRLSVLDLVVALAPCADEAAISKLYSTIRP------------YLESKAHGVQKKAYRVLEEVCASPQGPGALFVQSHLEDLKKTLLDSLRSTSSPAKRPRLKCLLHIVRKLS------------------------------------------------------------AEHKEFITALIPEVILCTKEVSVGARKNAFALLVEMGHAFLRFGSNQE-----------------EALQCYLVLIYPGLVG-AVTMVSCSILALTHLLFEFKGLMGTSTVEQLLENVCLLLASRTRDVVKSALGFIKVAVTVMD-VAHLAKHVQLVMEAIGKLSDDMRRHFRMKLRNLFTKFIRKFG--FELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQA-----AVEEEEE-EEEEEEPAQGKGDSIEEILADS-----EDEEDNEEEERSRGKE-------------QRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLAT-----------QPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGA-----------KGEDEEMADPMEDVIIRNKKHQKLKHQKEAEE----------------------EELEIPPQYQAGGSGIHRPVAK-------------------KAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRSKLNRRKK------------MKLQGQFKGLVKAARRGSQVGHKNRRKDRRP--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYA7-1", "uniprot_id": "RRP12_DROME", "id": "Q9VYA7-1", "name": "RRP12-like protein", "aln": "MGKFRSKLK-RNGKGKTWSRGESATSNPTQMKHRMKAKSRFFQPNLSLAAATTTGLTMEAVHKHEQSQAFNAETTTVNDVAGSLRSFKLDDDDDGMSGSGTAPTGTAPTGTIKTFQTFASNYSGCSNTCFQKLVTSFRSSSALHKEMLAILSALTEIIRENGGGESSTEYFLLLMEQIEAATEERD-----------IVAGVTLLAMGINSVPAPVLKKRFAQTADTMQRLLQRFMESTN----------QSVIRHVIGCLSVILRAQD---YAAWS-----YSSTFQYFDAILAFSIHSQ-PKIRKAAQHAIALIIHGSCFMLPAIKSDDNEMDEAVEQPKVKHHPASSRVAKFCLAQFKPEVLANAQTTVLHTLELLKDTLYGFKTEDIRSVCEHLLSIMTAANVLVRTNCFQTLYSLFLKKS-----PNLNASLCAKLLAAIHEYRPDKSDIRQTIAWVTVLKEGHLHLATMQLDLCMQALPRLIDVCTTDLWLSDQKELVAGVSNCIKELLQDCV-----SRACATAE-DAQCNR----QSVSRIIASLHKMLNAPFGEISRFVILIFSFVFEACGKLFGSELTPPLMTICKR-YDTQSAHRLQ--IEHTVISAIKALGPELVLTAIPLAD---GKGVMQLERSWLLPLLREGANGASLQFFKEKIVALAMDCQLKWKEFAEAKNNSSSHIYELLCCQLWGLFPGFCRQPRDPEY-LRYLAP-TLGAAVEKNPEFRPPIYDGLMELLGDNQSAECHQ-----------------------AIG-QYAKNFLPRLFNIYTQKPNGTYEADQRKRVLEVIRLYISRAPADVQLELFENAQEQLAASALAS--------------------------FEYDAFFDINAAIVRVQTCKGIKAYFDKYMAPILRNDKSKLVAKDEQKLKKQQRKTYELLRELMTSELPSCQKFTRKNSIVLQQILLDSFNTSCNVCQASRLHCLKSLIDCHSN----------------------------------------------------------LAYNDQLVMKAIPEAVLNYKEFSNYKEQVAEQLIKSITQLYHDAG----------------------KINDFVDILTAGFAG-DEMLVTNTILAFRAVLQQQGEHLTVATLEFVLQQVSVFLVQKSRKQAEAAIAFLITFIKVMP-IPLVANHLEAIMRSLSAMTKDTKRYCRIQIGYLLKKLCIRFS--PGELAGFVPGDDDVIHRRLKMIRKRTRRDLRKKQN-----LEAQEDSSDDELVSGLQEKSYTIDDMLADSDSDLPEDMDAKDEAGAAAAAS-------------KRSKNAKQQKSTYIREDPDEIVDLADLKSIGNVLTSGSAQTAT--PAQSQKTKAQLPNGGFKTADDGRLIISDKALRGQGGNDQSD-----------DDSDSDASMAYGTVAKQPKVKRGMEDDSSDEDKLQQKLVPKRVRKGDDAMSMKSGKTTASSRYTAGGKGIHRQLTAGNSDAMSVKSGKST-----SRPAGSEYGSKKAKGDMKKSGKLDPYAYIPLTRNNLNKRKR------------SMNSRKFKSVLRGAGAENGGAGGGRVSKKYK--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q54UV2-1", "uniprot_id": "Q54UV2_DICDI", "id": "Q54UV2-1", "name": "ETS domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------MSKTISELFPSLR--ENSSSETNKRLYAVLTAVTDLIRFNKAPINATSYFAIILKTITENKHKENQ----------TPDLLKLFSLILPQVSIPIIKNQSVNIILQMINILEKYVTQETTLNSTMSNDEQSLVKSGTYILGYVLVLAE---SNQWS-----TPEYLRGYSYILKLSVNNQQSKIRQKAAEQVILVLNSIGAIQTNAKGGG-------------VHKHLANVTSQFSHEIFTNVTHETMGTAFYALNIVTEALCLLPPSLISLLLEDIIKLTSLSNSPLTIACYKAIGSLFFKTN------PLIGSHIQQLIEVLFQHPPSGIDYKSTVSYTELLTQSYLYFVKLEPKLCNQHVHKYFSILMN-NFGSDKAEITKCTMNGFKSVIYECINLEVIQQGIYSFQ-QGSGNANRELSPLESIISTIESGLRLTFKSSWDLVLMIISALFEQLGPNAYPIMNNTLAGLDQLYHSPEFHFQTH--CRQVFIQVLSSIGPKNFLKILPLNLESHPNDKIKINRNWLLPLMRDNIKYTQLSFFIEYFYPMAIAMKERGKQVEMDGRLVEAKNLEILYSQVWDLLPGFLNHPLDSDVSFRVIAR-NLGVALSDEPGLRIVICAALTQMINKLKDTQITKPPVYIPLRKQHHLVTQERATQLLKSVSVFSKNYLPILFNIFPTS-----NQDQRYYILNAIEALVSITDSINLNTIFNSLITKLVEALTLEGIEKKPTQNSMDTTTTTTTTTTPKEKTKKYYLTDLTIGFVKHLDEENIKVLYKIIKP------------QLKCSDPGLQKRSYKILVKICEYHES----FILQNLTKIKALLVSNLMQSPSTIKKTRLKCLREIIISLTKSSYNKHLLTEEELELVAINENEKQLENTTTTTTTTTTTTTTTTTSTDNKPKVKVNIGWVQLKTKFIPSLIPEIILCTKETNVKCREIANELIIEIGKVMCLISAKLVKPKKGVSMEDTITIAHNEAIHEYLQLMMAGLASITPHMVSASIVSIARVIHEFYRDINEEFVGQLVTTVLVLLASPHREIVKAVFGLVRVVIATFKDTKSIESQLEVLVNGLAKWGGIDKNYFRTIVQILLERLIKRFG--FDQIYQLVPEDFKKVVTNIRKKNEKKEKAKELSRNGGGVDSNENMDENGDDSKSQKSKKNKKSKNTSGGGGDDDDEQMLASDEEHSDRDHSEDDADIEEFLFNVKPKKTKKDTKDNFLIKEGEDPIDFLDRNAFSHLSAKAAADIVAKQMFAKAAKNGGKLQNPFQLDEDGRMIIESSDSEDEGQKRKRERKKSFLDQVFEENEEAYERKAGYHVTKAKGLKNKFKQDNHDNSDYSDDDIDENLSRYNDDLKSNFTRRTNAKSVRGGGGGAKSVMGGAKSVKSTRTTNNNNKNEGRIETATLRYNRVRGVDHLVNYQDRDNKSTKTVAKTKGDNRKRDQKFEPY-----SYIKLDPKALNKRKGARPTSFTNVKKKGGKK--------", "tax_id": 44689, "tax_name": "Social amoeba" }, { "uniprot_ac": "Q12754-1", "uniprot_id": "RRP12_YEAST", "id": "Q12754-1", "name": "Ribosomal RNA-processing protein 12", "aln": "-----------------------------------------------------------------------------------------------MDQDK-------------------VAFLLELEDKLAKIRSQVNSKLENQKHIAIILTAVEENIAGQATNDVSKNIVNYIISFMSLLDQAVDPSTHEIKDIQLASSSTYLLDLIFHYSPKVLLRSKFSEILTKIAPCITAEKANAP------------LIRAAIGCLESLLIAQD---AQAWNNTYDLNVTPKRGLQGILELSLDVR-PKVRKRALDAVHAVLLNPPVAPTAEHVAAVFVADFCDKQLAGILNDLSNLSNKQLKAQKTKEDINASVMRSLRLITSVVSTGQWPSSQIEPLCDVLLGVTKSSEQYLVSASFECFESMFKTMAETTISSGLAENKYLRVLDTIFALKPSNVDTLLTKSWIAVVIKGMSTYATHQPLKALRKIPGVFHIMCT-YLASETPEVYQAASQCLISILSESVK---DDLLLYTPS-VDEKVFKNVDEIISQIAKTFIDFLSIRYSHCSREILKILVAAFNKFRYRSNPHFLKSLKIVDTWRVNEEQFMDLRNEIELVIGASISAMGPEMILAEAPLNLD--NPSSERPGRAWLLPLIRDYTKNANLATFQNELAPYIKSFQSKFDKVPEE--SIQLRVFQTIVDQIWSTLPRFCELPMDLRESFTDEFASELSSLLYSEVELRTTICHALKVLAESNVSYAEESSSHNVLLLQRFPISEAQKN---IEYLSTKSTNLLAVLFNVYTQT-----TPNARSYILETIDQYLKITSKEDLEKTFNNVCGLLKNSMNEE--------------SSGNVNKEKKKPQLTATLLDLIICMITYLPVSSYSALFSMFSLT------------VNSADALIQKRAYRIITKLSELKSGS--TAVAQFISDIENVMVDSASSVQTSAKAARLTAIKTIVELLP------------------------------------------------------------LDHLDFIVRTVAEVILSTKDVNEKSRETAFDTLICMGRKMNEPNGIIKLFQIPG--YDPTTPDQSSSISEFFKIISAGLIGESQHMVSSSITGYACLVFEFKNELDSGILMDIYDTIELYLTSNSREIVKSAIGFTKVCVLGLP-EELMRPKVPELLLKLLRWSHEHTGHFKAKVKHIIERLIRRFG--YDYIEANFPEEDRRLLTNIRKMRNRNKRKDEEVTTG----VSDVAATKGSRFMSAFDEAVYGSDEENDNG----------SDQEENVAGG------------------KMKNGAKQFIVESGDNPLDLLDSQTLAHISSTRPKK------FNKNQNRARFNDDAFNFDSEGKLVVKGQPKPSTNVDDPLS--------AVTSGINAYLEAVKSGPVRGQRNKLKFRKNGKDSD--------------------------------------------------------------------------------EFGDDDDGEKDSRLMRGRVNQGNK-------------------------IGKHNKKGPKFKSRKKL---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "F4IHU8-1", "uniprot_id": "F4IHU8_ARATH", "id": "F4IHU8-1", "name": "", "aln": "--------------------------------------------------------------------------------------------MELLCDDIGTSMCLTPSE---------PDLPVSEDFGEYMRSRLSQSKRPDHEHLCAVIEELSKTLAEDNHRRTPVAYFACTCRSLDSLFSAHAEPP-----VDVVQPHIVILSLVFPKVSAGVLKRD--GLALRLVLNVLRLKSATP-----------ECLISGLKCLVHLLTTVESIMVN----------EGSDSYNILLNFVTHSD-GKVRKLASSCLRDVLQKSHGTKAWQSVSG-----------AITEMFQNYLDLAHKSEVGSTEGARGAKQVLYILSTLKECLALMSKKHIATLIEGFKVLMILRDPYITRPVIDSLNAVCLNPTS----EVPVEALLEVLSLAAGLFSGHETSADAMTFTARLLKVGMTRSFTLNRDLCVVKLPSVFNGLND-IIASEHEEAIFAATDALKSLIFSCIDESLIREGVNEIRNSNLNVRKPSPTVIEKLCATVESLLDYKYHAVWDMAFQVVSAMFDKLGEHSAYFMRNTLQGLSDMQDLPDEGFPYRKQLHECVGSALGAMGPETFLSIVRLNLE---ANDLSEVKVWLFPILKQYTVGGRLSFFTEAIFSMVETMSHKAQKLKLQGLPVASRSVDSLVYSLWALLPSFCNYPVDTVESFADLGR-ILCGVLQTQAETHGIICASLNILIQQNKEVVEGKEVPTNDASPAMQRATARYDSQHAAANLKVLRLCAPKLLDVLSRIFHECSKDDGGS-LQSAIGNLASIAEKKTVSKLLFKTLQELLEATKTAIAQDESPVSG---MDVDNTADKNSSSNLRARLFDLLVSLLPGLDGQEVDTIFSSLKP------------AMQDSKGLIQKKAYKVLSVILKSSDG----FVSKN---LEELLVLMHNICHVSAKRHKLDCLYFLLAHASR-------------------------------------------------------TDDLKERKDIVSSFLPEVILALKEVNKKTRNRAYDVLVQIGHAYADEENGGD----------------NEKLHGYFDMVVGCLAGEKPQMISAAVKGVARLTYEFSDLISS--AYNLLPSTFLLLQRKNKEITKANLGLLKVLVAKSP-VEGLHANLKSMVEGLLKWPEGTKNLFKAKVRLLLEMLIKKCG--TEAVKSVMPEEHMKLLTNIRKIKERKEKKYAAGSD-----ISKSQHSKDTSSKVSRWNDTKIFSDVYADSEDSDGDDMDAESHGRSKASSLLKSKAS------ALRSKKSRNQSHLEVDESDDEPLDLMDQHKTRLALRS-----------SELRKRKADSDEEAEFDVEGRLVIREGERSKRKELSDADS----------DAKSSKGSRFSGNSSKKNQKRMKTSESGYAYT-------------------------------------------------------------------GKEYASKKASGDLKKKDKLEPYAYWPLDRKMMSRRPEQRAVAVRGMSSVVKMAKKMEGKSAAEALATTKFKKFKRSGQKKSAGKKKNK", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .*. ::.: :: : . : : . : :: : : . :: : : : * :* : :* : . *:*: * : :: . * : : : : . : . : : : . . :: . : : : * : . : : .:: ..: : : :. . * : : :. *: : * : . . : ::**: .* * : **:*:::: * * : . . : .. : : : .:* :* * * * : * : . : : .* : . . . *::: : ..* . : : . : . . *: : . :. : *:::*.:: : . :: :: : :* .: :: . . .:: :.* :* *: . .: * : : : : :. :: : . :: :: . : : : : : * :. .:: :.: . : : :: :: : : : :: : : . : .* : : .:: . : .: .: .. .. : :: ::: * : . . : : :*:::: . . . : : : .. . : ", "identical_positions": 42, "similar_positions": 246, "identity": "2.58%" }, { "cls_id": "homologset.oma.817370", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NHU3-1", "uniprot_id": "SMS2_HUMAN", "id": "Q8NHU3-1", "name": "Phosphatidylcholine:ceramide cholinephosphotransferase 2", "aln": "MDIIETAKLEEHLENQPSDPTNTYARPAEPVEEENKNGNGKPKSLSSGLRKGTKKYPDYIQIAMPTESRNKFPLEWWKTGIAFIYAVFNLVLTTVMITVVHERVPPKELSPPLPDKFFDYIDRVKWAFSVSEINGIILVGLWITQWLFLRYKSIVGRRFCFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKVQRILRLISGGGLSITGSHILCGDFLFSGHTVTLTLTYLFIKEYSPRHFWWYHLICWLLSAAGIICILVAHEHYTIDVIIAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCKKYSRVQKIGEDNEKST", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1S122-1", "uniprot_id": "F1S122_PIG", "id": "F1S122-1", "name": "", "aln": "MDIIETAKLEEHMENQTSEPANTYARPAEPIEEENKNGNGKPKSLSNGLRKGTKKYPDYIQIAMPTDSRNKFPLEWWKTGIAFVYALFNLVLTTVMITVVHERVPPKELSPPLPDKFFDYIDRVKWAFSVSEINGIILVGLWITQWLFLRYKSIVGRRFFFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKVQRILRLISGGGLSITGSHILCGDFLFSGHTVVLTLTYLFIKEYSPRHFWWYHLICWLLSAAGIICILVAHEHYTVDVIVAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCKKYSRVQKIGEDNEKST", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "E1BNX6-1", "uniprot_id": "E1BNX6_BOVIN", "id": "E1BNX6-1", "name": "", "aln": "MDIIETAKLEEHMENQTNDPANTYTRPPEPVEEENKNGNSKPKSLSNGLRKSTKKYPDYIQIAMPTEARNKFPLEWWKTGIAFVYALFNLVLTTVMITVVHERVPPKELSPPLPDKFFDYIDRVKWAFSVSEINGIILVGLWITQWLFLRYKSIVGRRFFFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKVQRILRLISGGGLSITGSHILCGDFLFSGHTVVLTLTYLFIKEYSPRHFWWYHLICWLLSAAGIICILVAHEHYTVDVIVAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCKKYSRVQKIGEDNEKST", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q4JM44-1", "uniprot_id": "SMS2_RAT", "id": "Q4JM44-1", "name": "Phosphatidylcholine:ceramide cholinephosphotransferase 2", "aln": "MDIIETAKLEGHLESQTNNSTNTYTSPTEAVEEEDKNGKGKPKTLSNGLRKGAKKYPDYIQISMPNDSRNKLPLEWWKTGIAFVYALFNLILTTVMITVVHERVPPKELSPPLPDKFFDYVDRVKWAFSVSEINGMVLVGLWLTQWLFLRYKSIVGRRFFFIMGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKIQRILRLLSGGGLSITGSHILCGDFLFSGHTVVLTLTYLFIKEYSPRHFWWYHLVCWLLSAAGIICILVAHEHYTVDVIIAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCKKYSRVQKIGEDNEKST", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D4B1-1", "uniprot_id": "SMS2_MOUSE", "id": "Q9D4B1-1", "name": "Phosphatidylcholine:ceramide cholinephosphotransferase 2", "aln": "MDIIETAKLEGHLESQTNDSTNTYTSPTEAVEEEGKNGKGKPKTLSNGLRKGAKKYPDYIQISMPNDSKNKFPLEWWKTGIAFVYALFNLILTTVMITVVHERVPPKELSPPLPDKFFDYFDRVKWAFSVSEINGMVLVGLWITQWLFLRYKSIVGRRFFFIMGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKIQRILRLISGGGLSITGSHILCGDFLFSGHTVVLTLTYLFIKEYSPRHFWWYHLVCWLLSAAGIICILVAHEHYTVDVIIAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCRKYSRVQKIGEDNEKST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3I338-1", "uniprot_id": "G3I338_CRIGR", "id": "G3I338-1", "name": "", "aln": "MDIIETAKLEGHLENQTNDSTNTYTGPADTVEEGNKNGNGKPKSLSNGLRKGAKKYPDYIQISMPTDSRNKFPLEWWKTGIAFVYALFNLVLTTVMITVVHERVPPKELSPPLPDKFFDYVDRVKWAFSVSEINGIVLVGLWITQWLFLRYKSIVGRRFFFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKIQRILRLISGGGLSITGSHILCGDFLFSGHTVVLTLTYLFIKEYSPRHFWWYHLVCWLLSAAGIICILVAHEHYTVDVIIAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCKKYSRVQKIGEDNEKST", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "F1NLG9-1", "uniprot_id": "F1NLG9_CHICK", "id": "F1NLG9-1", "name": "", "aln": "MNTIETAKLEDHMEGQNNDTANGYTRPTLSVSEENKNGNNKPKGLSNGLRKTAKKYPDYIQIAMPAESRNKFPLEWWKTGIAFVYALFNLILTTVMITVVHERVPPKERSPPLPDKFFDYIDRVTWAFSVSEINGMILVGLWIFQWLFLRYKSIVGRRFFFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKVQRILRLISGGGLSITGSHILCGDFLFSGHTVVLTLIYLFIKEYSPRHFWWYHLICWLMSAAGIICILVAHEHYTVDVIIAYYITTRLFWWYHSMANEKTLKVSSQTNFLSRAWWYPIFYFFEKNVQGSVPCSFSWPISWPPSCFKSSCKKYSRVQKTGEDNEKST", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "A0A8M1NT99-1", "uniprot_id": "A0A8M1NT99_DANRE", "id": "A0A8M1NT99-1", "name": "", "aln": "---MASSDHQGNKE--PTNTSRTDGAPSTGATCPVHSAEDAKR---NGLRKGLVRHRDYVKISVPEGKGNRLPSEWWKTFIALFYAALNLVLTTVMITVVHERVPPKEESPPLPDKFFDYIDRVQWAFTVTEVNGMVLVSIWGIQLLFHRYKAIVARRYFFLLGTLYMYRCITMYVTTLPVPGMHMVCAPKLHGDSEAKLQRVLQLLSGGGLSINGSHLLCGDFLYSGHTVILTLTYLFLKEYSPRSFWWYHLLCWLTAAVGVVCILVAHEHYSVDVVVAYFITTRLFYWYHTMANLQTLKCS-PNNYLTHTWWNPVFNLFERNVQTHVPCSFCWPITWPPACLKNPCKKYSMVQSGREE-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::. : : * .:.:. *. :..:. : .**** :: **::*::* *::* ***** **:.** :**:***************** ***********.*** ***:*:*:**::**.:* * ** ***:**.**: *::****:*****************: *****:***:**:**:*:*:*******.***:******:***** *** ***:****** ******:*** :*.*::*********::**::**:******:***:*** :.** * .*:*:::** *:* :**:*** :**.*.**::***.*:*..*:*** **. *: ", "identical_positions": 210, "similar_positions": 90, "identity": "57.53%" }, { "cls_id": "homologset.oma.817371", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q96LT4-1", "uniprot_id": "SAMD8_HUMAN", "id": "Q96LT4-1", "name": "Sphingomyelin synthase-related protein 1", "aln": "---------------------------------------------------------------MAGPNQLCIRRWTTKHVAVWLKDEGFFEYVDILCNKHRLDGITLLTLTEYDLRSPPLEIKVLGDIKRLMLSVRKLQKIHIDVLEEMGYNSDSPMGSMTPFISALQSTDWLCNGELSHDCDGPITDLNSDQYQYMNGKNKHSVRRLDPEYWKTILSCIYVFIVFGFTSFIMVIVHERVPDMQTYPPLPDIFLDSVPRIPWAFAMTEVCGMILCYIWLLVLLLHKHRSILLRRLCSLMGTVFLLRCFTMFVTSLSVPGQHLQCTGKIYGSVWEKLHRAFAIWSGFGMTLTGVHTCGDYMFSGHTVVLTMLNFFVTEYTPRSWNFLHTLSWVLNLFGIFFILAAHEHYSIDVFIAFYITTRLFLYYHTLANTRAYQQSRRARIWFPMFSFFECNVNGTVPNEYCWPFSKPAIMKRLIG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1MYS1-1", "uniprot_id": "F1MYS1_BOVIN", "id": "F1MYS1-1", "name": "Sphingomyelin synthase-related protein 1", "aln": "MPARSRHRPSLHSGSPTRAPPPPLEASLSREARRAPDSGSGSDADPETGPGTPIRNKETVEEEMAVPNQLCIRRWTTKHVAVWLKDEGFFEYVDVLCNKHRLDGITLLTLTEYDLRSPPLEIKVLGDIKRLMLSVRKLQKIHIDVLEEMGYNSDSPMSPMTPFISALQSAEWLCNGEPSHDCDGPITDLNSDQYQYVNGKNKHSIRRLDPEYWKTILSCIYVFIVFGFTSFIMVIVHERVPDMQTYPPLPDIFLDSVPRIPWAFAMTEVCGMILCYIWLLVLLLHKHRSILLRRLCSLMGTVFLLRCFTMFVTSLSVPGQHLQCTGKVYGSVWEKLHRAFAIWSGFGMTLTGVHTCGDYMFSGHTVVLTMLNFFVTEYTPRSWNFLHTLSWVLNLFGIFFILAAHEHYSIDVFIAFYITTRLFLYYHTLANTRAYQQSRRARIWFPMFSFFECNVNGTVPNEYCWPFSKPAIMKRLIG", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A9J7J640-1", "uniprot_id": "A0A9J7J640_CRIGR", "id": "A0A9J7J640-1", "name": "Sphingomyelin synthase-related protein 1", "aln": "MPARSRAGSRLRSGSPPRALRLPFEALLSADAPRTPDSDGAPDAGSELGPGSSAPTAEAVEEEMAGPSQLCIRRWTTKHVAVWLKDEGFFEYVDILCNKHRLDGITLLTLTEYDLRSPPLEIKVLGDIKRLMLSVRKLQKIHIDVLEEMGYNSDSPMSPMTPFINALQSADWLCNGEPTHDCDGPITDLNSDQYQYMNGKNKHSVRRLDPEYWKTILSCVYVFIVFGFTSFIMVIVHERVPDMQTYPPLPDIFLDSVPRIPWAFSMTEVCGMILCYIWILVLLLHKHRSILLRRLCSLMGTVFLLRCFTMFVTSLSVPGQHLQCTGKIYGSVWEKLHRAFAIWSGFGMTLTGVHTCGDYMFSGHTVVLTMLNFFVTEYTPRSWNFLHTLSWVLNLFGIFFILAAHEHYSIDVFIAFYITTRLFLYYHTLANTRAYHQSRRARIWFPMFSFFECNVNGTVPNEYCWPFSKPAIMKRLIG", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** *.**************************:**************************************************************..*****.****::****** :*****************:*******:**************:********************************************:*************:************************************************:***********************************************************************************************************:******************************************", "identical_positions": 398, "similar_positions": 15, "identity": "83.26%" }, { "cls_id": "homologset.oma.817372", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TSX5-1", "uniprot_id": "SMS1_RAT", "id": "Q7TSX5-1", "name": "Phosphatidylcholine:ceramide cholinephosphotransferase 1", "aln": "MLSASTMKEVVYWSPKKVADWLLENAMPEYCEPLGHFTGQDLINLTQEDFTKPPLCRVSSDNGQRLLDMIETLKMEHHIEAHKNGHANGHLSIGVDIPNPDGSFSIKIKPNGMPNGFRKEMIKIPMPEPERSQYPMEWGKTLLAFLYALSCFVLTTVMISVVHERVPPKEVQPPLPDTFFDHFNRVQWAFSICEINGMILVGLWLFQWLLLKYKSIISRRFFCIVGTLYLYRCITMYVTTLPVPGMHFNCSPKLFGDWEAQVRRIMKLIAGGGLSITGSHNMCGDYLYSGHTVMLTLTYLFIKEYSPRRLWWYHWICWLLSVVGIFCILLAHDHYTVDVVVAYYITTRLFWWYHTMANQQVLKEASQMNLLARVWWYRPFQYFEKNVQGIVPRSYHWPLPWPVVHLSRQVKYSRLVNDT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCQ6-1", "uniprot_id": "SMS1_MOUSE", "id": "Q8VCQ6-1", "name": "Phosphatidylcholine:ceramide cholinephosphotransferase 1", "aln": "MLSARTMKEVVYWSPKKVADWLLENAMPEYCEPLEHFTGQDLINLTQEDFKKPPLYRVSSDNGQRLLDMIETLKMEHHMEAHKNGHANGHLSIGVDIPNPDGSFSIKTKPNGMPNGFRKEMIKIPMPEPERSQYPMEWGKTFLAFLYALSCFVLTTVMISVVHERVPPKEVQPPLPDTFFDHFNRVQWAFSICEINGMILVGLWLFQWLLLKYKSIISRRFFCIVGTLYLYRCITMYVTTLPVPGMHFNCSPKLFGDWEAQVRRIMKLIAGGGLSITGSHNMCGDYLYSGHTVMLTLTYLFIKEYSPRRLWWYHWICWLLSVVGIFCILLAHDHYTVDVVVAYYITTRLFWWYHTMANQQVLKEASQMNLLARVWWYRPFQYFEKNVQGIVPRSYHWPFPWPVVHLSRQVKYSRLVNDT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86VZ5-1", "uniprot_id": "SMS1_HUMAN", "id": "Q86VZ5-1", "name": "Phosphatidylcholine:ceramide cholinephosphotransferase 1", "aln": "------MKEVVYWSPKKVADWLLENAMPEYCEPLEHFTGQDLINLTQEDFKKPPLCRVSSDNGQRLLDMIETLKMEHHLEAHKNGHANGHLNIGVDIPTPDGSFSIKIKPNGMPNGYRKEMIKIPMPELERSQYPMEWGKTFLAFLYALSCFVLTTVMISVVHERVPPKEVQPPLPDTFFDHFNRVQWAFSICEINGMILVGLWLIQWLLLKYKSIISRRFFCIVGTLYLYRCITMYVTTLPVPGMHFNCSPKLFGDWEAQLRRIMKLIAGGGLSITGSHNMCGDYLYSGHTVMLTLTYLFIKEYSPRRLWWYHWICWLLSVVGIFCILLAHDHYTVDVVVAYYITTRLFWWYHTMANQQVLKEASQMNLLARVWWYRPFQYFEKNVQGIVPRSYHWPFPWPVVHLSRQVKYSRLVNDT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A3Q1M660-1", "uniprot_id": "A0A3Q1M660_BOVIN", "id": "A0A3Q1M660-1", "name": "Phosphatidylcholine:ceramide cholinephosphotransferase 1", "aln": "------MKEVVYWSPEKVADWLQENAMPEYCEPLEHFTGRDLINLTQEDFTKPPLCLVTSDNGQRLLHMIETLKMEHHLEAHKNGHANGHLSIGTGSPSPNGSFSIKVKPNGMPNGYRKEMIKIPMPEPERSQYPMEWGKTFLAFLYALSCFVLTTVMISVVHERVPPKEVQPPLPDTFFDHFNRVQWAFSICEINGMILVGLWLIQWLLLKYKSIISRRFFCIVGTLYLYRCITMYVTTLPVPGMHFNCSPKLFGDWEAQLRRIMKLIAGGGLSITGSHNMCGDYLYSGHTVMLTLTYLFIKEYSPRRLWWYHWLCWLLSVVGIFCILLAHDHYTVDVVVAYYITTRLFWWYHTMANQQVLKEASQMNLLARVWWYRPFQYFEKNVQGIVPRSYHWPFPWPVIHLSRQVKYSRLVNDT", "tax_id": 9913, "tax_name": "Bovine" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *********:****** *********** ****:**********.**** *:********.**********:************.**.. *.*:****** ********:*********** ************:***************************************************************:*******************************************************:*****************************************************:**********************************************************************************:****:***************", "identical_positions": 388, "similar_positions": 18, "identity": "92.6%" }, { "cls_id": "homologset.oma.817419", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BIW9-1", "uniprot_id": "CTF18_MOUSE", "id": "Q8BIW9-1", "name": "Chromosome transmission fidelity protein 18 homolog", "aln": "MEDYEEDLYGVEDDFQNQFAAELEVLAELEG-TRDQAPPGTLQTPASRPPLTFEEAIAGGDTVPRPCPAGSPGNVNRNTRKN-VRRD-QPA---PSSPMVKRPRLDVVKKLNFEP-DMEELLYPDSP---PGDITPPP------SPEVFPEMLDAGYSDANADKDLMQTLP----------------SPRNRNPVLRRPPILEDYINVTSTSGERAFLVLRADL---------IGPGVQNPLLDVHWRGCGQLDLLGVPFASLKEQVDSKRRQQLLEDAQQLSDTLHSLRS-EGEEA---------VLEGPPAEEPAPGQNTAQHCLWVDEFAPQHYTELLSDDFTNRCLLKWLKLWDLVVFGRERPARKPRPGVETTR-VGKEAT--------APGKWKS----HEQALEEMLEAELDPSQRPRQKVALLCGPPGLGKTTLAHVVARHAGYCVVEMNASDDRSPEAFRTRIEAATQMESVLGVGGRPNCLVIDEIDGAPTA-AINVLLGILNRKGPQEADQGGTAVAAGG-RRRRAEGGLLTRPIICICNDQFTPSLRQLKQQALLLHVPPTLPSRLVQRLQEISLQHGMRSDPGALVALCEKTDNDIRACINTLQFLYGRGRRELSVKAVQTTHVGLKDQRKGLFSVWQEVFQLPRTQRRIVGQDLMLPAHALLLSN-----GDKGSLTLASQRFYHILRVTTSAGEHEKVVQGLFDNFLRLRLRDSSLSTVCCALDWLAFDDLLEQAAHRGQSFQLLCYLPFVPAAFHVLFASSHVP-RITFPSSQQE---AQTRMSQTRNHIQTLVSGMAPTTRSRATPQALVLDTLCLLLDVLAPKLRPVSTQLYSAHEKQQLSCLVGTMLAYSLTYHQERTPDGQYLYKLEP---------------------------------------NVEEVCRFPELPARKPLTYQAKQLIAREIEMEKMRRAEALAWARSGPQVDQGSSGPASLWTDSGEKGTRQPAPRNHEQRLEHIMKRATVQEQPERDFFGRVVIRKVAVPSREVEAPQKDADEWRMGVAVGRSEVWFRFNEGVSNAVRRSLYIRDLL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3HBV4-1", "uniprot_id": "G3HBV4_CRIGR", "id": "G3HBV4-1", "name": "Chromosome transmission fidelity protein 18 homolog", "aln": "MEDYEEDLYGVEDDFHNQFAAELEVLAELEAGTQDLASSGNLQTPASRPPLTFEEAIAGGDTAPRPCPVGSPENDCRNTRKN-VRRD-QPG---PSSPMIKRPRLEVVKRLNFEP-DTEELLYPDSP---PGDITPPP------SPEVFPEILDPGPSDDSADKGTMQALP----------------SPR--NPVLRRPPVLEDYINVTSTSGERAFLVLRADL---------TGTGVQNPPLDVQWRGHGQLGLLGVPFASLKEQVDNMRRQQLLEEAQELSDTLHSLRS-ERVDA---------LLEGTPEEDPAPGQHTTQHCLWVDAFAPQHYTELLSDDFTNRCLLKWLKLWDLVVFGHERPARKARPSIEPTR-IGKEAT--------APGKWKS----HEQVLEEMLEDELDPSRRPRHKVAMLCGPPGLGKTTLAHVVARHAGYCVVEMNASDDRSPEAFRTRIEAATQMESVLGAGGRPNCLVIDEIDGASTA-AINVLLSVLNRKGPQEAEQGDTAAPAGG-RRRRAEGGLLTRPIICICNDQFTPSLRQLKQQAFLLHVPPTLPSRLVQRLQEISLQHGMRSDPGALAALCEKTDNDIRACINTLQFLYGRGRRELSVRDVQTTHVGLKDQRKGLFSVWQEVFQLPKAQRRVVGQDLILPTHALLLND-----GDKGSLTLASQRFYHILRVTTSAGEHEKVVQGLFDNFLHLRLRDSSLGTVCCALDWLAFDDLLEQAAHHGQSFQLLRYLPFLPAAFHVLFASSHVP-RITFPSSQQE---AQTRMSQTKNHIQTLVSGMAPSTRSRATPQALVLDTLCLLLDVLAPKLRPVSTQLYSAREKQQLSSLVGTMLAYSLTYHQERTPDGQYLYRLEP---------------------------------------NVEEVCRFPELPARKPLTYQAKQLIAREIEMEKMRRAEALALARGGPQVDQGPSGPASLQTDSGDKGVRQPAPRNHEQRLEHIMKKAVVQEQPERDFFGRVVIRRVAVPSREAEAPEKDTDEWRMGVAVGRSEVWFRFNEGVSNAVRRSLYIRDLL-", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q8WVB6-1", "uniprot_id": "CTF18_HUMAN", "id": "Q8WVB6-1", "name": "Chromosome transmission fidelity protein 18 homolog", "aln": "MEDYEQELCGVEDDFHNQFAAELEVLAELEG-ASTPSPSGVPLFTAGRPPRTFEEALARGDAASSPAPAASVGSSQGGARKRQVDADLQPAGSLPHAPRIKRPRLQVVKRLNFRSEEMEEPPPPDSS---PTDITPPP------SPEDLAELWGHGVSEAAADVGLTRASP----------------AAR--NPVLRRPPILEDYVHVTSTEGVRAYLVLRADP---------MAPGVQGSLLHVPWRGGGQLDLLGVSLASLKKQVDGERRERLLQEAQKLSDTLHSLRSGEEEAA---------QPLGAPEEEPTDGQDASSHCLWVDEFAPRHYTELLSDDFTNRCLLKWLKLWDLVVFGHERPSRKPRPSVEPAR-VSKEAT--------APGKWKS----HEQVLEEMLEAGLDPSQRPKQKVALLCGPPGLGKTTLAHVIARHAGYSVVEMNASDDRSPEVFRTRIEAATQMESVLGAGGKPNCLVIDEIDGAPVA-AINVLLSILNRKGPQEVGPQGPAVPSGGGRRRRAEGGLLMRPIICICNDQFAPSLRQLKQQAFLLHFPPTLPSRLVQRLQEVSLRQGMRADPGVLAALCEKTDNDIRACINTLQFLYSRGQRELSVRDVQATRVGLKDQRRGLFSVWQEVFQLPRAQRRRVGQDPALPADTLLLGD-----GDAGSLTSASQRFYRVLHAAASAGEHEKVVQGLFDNFLRLRLRDSSLGAVCVALDWLAFDDLLAGAAHHSQSFQLLRYPPFLPVAFHVLFASSHTP-RITFPSSQQE---AQNRMSQMRNLIQTLVSGIAPATRSRATPQALLLDALCLLLDILAPKLRPVSTQLYSTREKQQLASLVGTMLAYSLTYRQERTPDGQYIYRLEP---------------------------------------NVEELCRFPELPARKPLTYQTKQLIAREIEVEKMRRAEASARVENSPQVDGSPPGLEGLLGGIGEKGVHRPAPRNHEQRLEHIMRRAAREEQPEKDFFGRVVVRSTAVPSAGDTAPEQDSVERRMGTAVGRSEVWFRFNEGVSNAVRRSLYIRDLL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0Z6W8-1", "uniprot_id": "A0A8V0Z6W8_CHICK", "id": "A0A8V0Z6W8-1", "name": "Chromosome transmission fidelity protein 18 homolog", "aln": "-----MESPGDEDDFTERFAAELEVLAELEDYPSSPGPR--VSQFRSRKQLQDEAGPAVGPNAKKRSQECALHPSPPPSPPAGSPMA--------LTPKPKRQRLEAVKKLNFGG---DGELAPDVF---QDAVTPVPGSASPRGPHAARSQAFPSPELEVSGLGPLQSSP----------------PTENPKRVLRRPPILGDYINVTSSEGTRVFMAVRDDS---------SHIGIELR-DSVGWN--RPLHLLGVPFSYLKEQVYEEHRRRAVEVSQQLTETINSCSETSDEAT---------EQPGDTGEE-----EPTPHCLWVDKFAPRRYIELLSDDYTNRCLLKWLKLWDTVVFGKEKPVKKAKPGAEAHPPFRQHKE--------QQNKWKT----KAQLTEEILEAELDQHKRPKYKVALLCGPPGLGKTTLAHVIARHAGYNVVEMNASDDRSPETFRIRIEAATQMKSVLGAEEKPNCLIIDEIDGAPTA-SITVLLNIINSKEPE-----GEAAASGG-RRRRREGSLLLRPVICICNDQYVPALRPLRQQAFLLSFPQTAPSRLAQRLGEIAQQQGMRADMGALLALCKKAENDIRSCINTLQFLHSRGQKELDVRVVQTMKIGLKDQNKGLFSIWQEIFQLPRVQRHHIGMDPSLPNHLLADEDEMSHLGVRTALTASSHRFHRVLHLASSSGEQEKLAQGLYENFLNMKLRDSSFSSVCLALEWLCFSDMLGRAVLHGQSFQLMRYLPFLPVAFHMLFAATSIP-RLSYPSSHHE---ALAKLNHMQNLMVSMVSGITPSARSRAGQQSLVLEVLCLLLDIIAPKLRPVNTQLYSLKEKQQLAALISTMLAYNLTYHQERLPEGQYVYKLDPNAHRTAGVGAWPPCAAHPLLLSPPYAMAVTAPCPYGILRNVEDVCRFPDLPARKQLTYQAKQLIAHEIEMEKMRRTEAVLQARN---LNEEP----MEMGDVEMKAGGPPVPHNHQQRLEHIVRRAAVRDKPETDFFGRPIQRQQSAPALEAQPAEHDAIEHQMGKAVGRSDVWFRFNEGVSNAVRRNLYIRDLL-", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "F1QF60-1", "uniprot_id": "F1QF60_DANRE", "id": "F1QF60-1", "name": "Chromosome transmission fidelity protein 18 homolog", "aln": "-MDEYDEMYGIEDDFERQFADELEVMAELES--NNPPAAKVSEFRNKPITQTFEEALVSGDQPSRKSVNNQNPESISPPVYEEEEES--------LTPKPKKRRQDVAKKLQFGVDQDDDITPPSSPEVYDREVRDGPRFSLTLSPDRPAATKITTNVLDISGLGALQESPK--------------QVTAAKRHAQKRPPAIGDYITVTDSMGNRVYLNKKEDV---------EKT----PDPRAFRNSLNGLGLLAVPIEVLKEQIAERRHRQVVEESQRLTELMKSGID-SDLLA---------EEQTDSGVDGDSGEDEASSRLWVDQFSPQHYTDLLSDDFTNRCLLKWLKLWDTVVFGRERKSRPVPVEARSNFTNAQNQN--------QAQRFKT----KSQMTEEILEAELDQYKRPKFKVALLSGPPGLGKTTLAHIIAKHAGYNVVEINASDDRSAELFQKRIDTATQMKSVLGANEKPNCLIIDEIDGAPAA-AINILLATLNRKDSKD----GEETGVNALKKKKKKQSVLLRPIICICNDLYVPALRPLRQQAFLLVFPQTLPSRLAQRLAEISRRQGMKADTGTLMALCEKTDNDIRSCINTLQFLHSRGQKHLDQRSVSSMCVGLKDQNKGLFSVWQEIFQLPRLKRKRIGGDPFSGYDELGPKE-------------GAQRLQHILHLVSSTGEHEKLTQGLYDNFLSMKLKDPGMLGVCSGLDWLCFSDLLNECVLHGQNYSLMRYFPFLPAAFHQLYAATSVP-RINYPHSHYE---AFTKTQHIRNALLAMLNDIPPAIQSRVCMSSLCLDILSLLLELISPKLRPVNPQLYSTREKQQLYDLIDTMINYNLTYRQDRTPEGQYTYVLEP---------------------------------------NIEDVVNYPGLPPRRQLTYQVKQLIARETELERMRRVERAQQSRNPQKMETVN-----KNQEEKKTEVKKQTSRNHQQRLENIVKQTVVETRPELDFFGRAIVPKEKPVVTATSEDGKVSGVLNIGKAVGNSDVWFRFNEGVSNAVRRNVYIRELL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQ05-1", "uniprot_id": "CTF18_DROME", "id": "Q8IQ05-1", "name": "Chromosome transmission fidelity protein 18 homolog", "aln": "----MDQYPDENEEFELQYQDELELLEDLPDEFNAYDGPSTSKQAAEKQKENRAPVAALRDSTRLGNSTLGSPQLSQITFGASQLGGEEEAEGTSSGGQVNRRLFGTPKGPPVGR--GCSTPFQRMPAIQELENTQLTSRSYGLEKENAAANQLQEVGLKNVNKRRLERDLFGDIDDLFHESYEDPMVKKARTEEQRDHEAIERILELRRKMRESSKTLRKDDVSRLKALHDFKMRNLSYEIPNWPFLAIQRSDLERIYVRFHSEDYEQRQLDLISARGEVVGSLLGEAKDKIWQEAGEIVLSRATAAEDADVTLVNSNANSEPGRLWVDKYKPRKYIDLLSDEMTNRSLLYWLKMWDKVVFGKAFHSKREQEAVTGEGGTAGGAANQLNSFNKRTGKFESNGGWRQRKSRQALNTNVDALGRPMQKVALLCGPPGLGKTTLAHTIARHAGYNVREINASDDRSPEAFKLALENGTQMSSVLNEDKRPNCIVLDEIDGAPRQ-SIDYLVKFIS----------DAVYTKVKAKGAKAEHNVLKRPIICICNDVYDPALRPLRQVAFVVTFPPIDAARLAERLVKIAFKEQLKTDFGSLIALAEKSGNDVRSCISSMQFFN-AQKHSLTLQDVLNNNLGQKDRHQGLFAVWDAIFRIQRPRKTLHTDANKVDEPAQVTMTN----------TSVTTRVRNVLEVVHSSGDYERLTQGVYENYLQQKMPDPNFTGVCEALKWFCFTDTVQHQISRQQNYSVYPYLQYGFVAWHLLFATLAWP-KIAFPTRGFE---FQQKSTNQRNIFQALCKGVTTSALGVGQGGTLLLDTVPLLKRILSPQLRSVAVQLLSPKEQQDLRHTIEVMVDLGLTFVQVKSQEGHYVFQTEP---------------------------------------DLDALSAFPGYTG-LSLPYFSRQLIAREVDLERIRRAAPKGGAPSAPAAKKKTSGAAAQLPNHLQTLKPKPISASNMH--------SAPKQQLTKDFFGRITHKSTSTNSAEESKTD----------AIVKSPIWYRYKEGFNNAVRKDVHIHELL-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P49956-1", "uniprot_id": "CTF18_YEAST", "id": "P49956-1", "name": "Chromosome transmission fidelity protein 18", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MVDTAPYIGSLGRSSLFDTGDIEQAP----------------------GNNAIGINEEDIHAFVSSTGETVQLKKKPAK----------------------LATGNISLYTNPDTVWRSDDTYGININYLLDKIEASGDDRTNAQKTSPITG-----------------------KIGSDTLWVEKWRPKKFLDLVGNEKTNRRMLGWLRQWTPAVFKEQLP--------------------------------------KLPTEKEVSDMELDPLKRPPKKILLLHGPPGIGKTSVAHVIAKQSGFSVSEINASDERAGPMVKEKIYNLLFNHTFDTN---PVCLVADEIDGSIESGFIRILVDIMQSDIKATNKLLYGQPDKKDKKRKKKRSKLLTRPIICICNNLYAPSLEKLKPFCEIIAVKRPSDTTLLERLNLICHKENMNIPIKAINDLIDLAQGDVRNCINNLQFLASNVDS----RDSSASDKPACAKNTWASSNKDSPISWFKIVNQLFRKDPHR---------------------DIKEQFYELLNQVELNGNSDRILQGCFNIFPYVKYSDNGIRKPANISDWLFFHDLMYQSMY-AHNGELLRYSALVPLVFFQTFGDIANKDDIRMKNSEYEQRELKRANSDIVSLIMRHISVQSPLMASFTDRKSLIFEILPYLDSMISSDFNKIRNLKLKQAIMEELVQLLKSFQLN-LIQNRSEGFDVRGGLTIDP---------------------------------------PIDEVVLLNPKHINEVQHKRANNLSSLLAKIEENRAKKRHIDQVTEDRLQSQE-----MHSKKVKTGLNSSSSTIDFFKNQYGLLKQTQELEETQKTIGSDETNQADDCN-------------------QTVKIWVKYNEGFSNAVRKNVTWNNLWE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : ..: . : . . . . ***: : *::: :*:.:: *** :* **: * .** . : .: : :* ** *: :* ****:***::** :*:::*: * *:****:*: .: : :. * *:: *****: * *: :. : : . :* **:*****: : *:*. *: . :: . : * :** :. :. :. : * . : .*:* **..:**: : :. : : : : . :. .:*. . *: ::: ** :: : : * .: . .*: * * : :. .: * .:. :. : * . . : . .. . :* :: : * :::..:. : . ::* : : * : . : : :* :: : .:* : .:*. * . . . . . . . . :* :* :::**..****:.: .:* ", "identical_positions": 94, "similar_positions": 184, "identity": "8.67%" }, { "cls_id": "homologset.oma.817420", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F4I5S3-1", "uniprot_id": "F4I5S3_ARATH", "id": "F4I5S3-1", "name": "Chromosome transmission fidelity protein 18 homolog", "aln": "------------MEFDIPLPEELELLEANS-------------------HFYEEEDEYLNFEEPPYPYPIDGDEEKEEERVAHKEPHVRQS---ESSDIKGCKRPRSLISDPIVNLDEVSPASDKRSKIDDNRVEIEDEDWLRFSPVKEVVHVMEEEEEVVIPQETMLSRYASEIDGE--------CFPITAPDGGDRVYAKFCRALGDEEVNKLDVKDKSNGLIKDPISVLLQQSEKEAFNKVLQASSED-------QNETISAETSVMHEKLWVDKYSPSSFTELLSDEQTNREVLLWLKQWDASVFGSEIRSTTEAVLSALKRHSTTSHHQKSDSAFTRKKQFNRWSKESFGYSKNAEVSNTNTADINDLWNKKS----KLTGPPEQKILLLCGAPGLGKTTLAHIAAKHCGYRVVEINASDERSASAIETRILDVVQMNSVTADS-RPKCLVIDEIDGALGDGKGAVDVILKMVLAERKHATGKENVEN-------------------------------------VKTSSKKDRR---TAPLSRPVICICNDLYAPALRPLRQIAKVHIFVQPTVSRVVNRLKYICNMEGMKARSFALSALAEYTECDIRSCLNTLQFLYKKKETIN---VIDIGSQVVGRKDMSKSLFDIWKEIFTTRKMKRER-------SNDASGSG----------AKNFDFLHSLVSSRGDYDLIFDGIHENILQLHYHDPVMDKTISCLDGLGTSDLLHRYIMRTQQMPLYVYFPSLVIPIHRRVAQIQKPMIEWPKSYHRCRTLLVEKQESLRSWHHKIPPYIGRHLSIKSFVEDSISPLLHILSPPTLRPVASHLLSDRQKEQLAGLVMLMCSYSLTYKNVKSDPVLSSLREDAASDALVLALDPHLFDFINFKGHQFKHHVLALAMKQVLVHEVEKQKILQASGGKSG------------------ILNKPEIKKINQ------------------DLAKKTNAAANESQRTPVTSKPPSVSVGTATTSKPNSSDVKKASRNALN-------------FFDRFRKSRKD------YEDPEDVQNRATAKRDSRPLLFKFNEG------------------------------------------------------------------------FTNAVKRPVRMREFLL-----------------------------", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q86L47-1", "uniprot_id": "Q86L47_DICDI", "id": "Q86L47-1", "name": "", "aln": "-----------------MLGTKRNLSDTND-------------------IINDEN------------VDNNSNDNSNKRFKTNSISFEKKS---NPPSLSTTTTTTTTTTTTTTITSTIPLGSQKRINITS----FSGHRITRVVKSQNSENISTSLSKSNILFNDLLKKPINEIL---------------------------------EEIENIESLKLKSELIKNSNSLTPTKSKGVSEEIVKNKDN-----------------------RLWVDKYAPTSFHDLLSDTTMNLEVLNWLELWDHIVFDKPLS-KNLIMPSTFNNNNNNNNNNNNNNNNNNNNNNKNSSSTGGGYFNKFNSKFTTSSNSNQQHQNQGQYLLQEDGTPIAKIILLTGGPGLGKTTLAHVLAKQANYNPVEINASEDRSGEAFESKLLSAIEMKSLFNDN-KPNCLIIDEIDGISGRDNGPIELLIKLIDNSLKLGNHKKSTTNPAAKKSAGKDTESDDDDDDDDDDDDDHEDQDEDDEKSTKTKGKKGKKKGFTTRLLRPIICICNDQYVPSLRKLRQKAMVFDFQAPKKNDLLSRLKVICSNEGLSATDATLNALIDMTGSDIRACINSLQFIKSKTTVLNSELLKNKSNIVIGQKDMEKGLVEIWNNIFKSSSITSSTN-KLSKYSNTISSSSSSIDSINSISNDYLNQLDFQIGACNQVDKLIDGVYENYLTNMSSDYTMQKTMDCLDWMVFGDQMLN-------VHADEKYRSLVPLAIHQRCSTYSPKIQLPHSDYDNFIKKKSNSNIKDSFYSDLPATIYSYLTKKCFVIDFIYPFVDILSLP-VRVTNVQLYSQTEKTNLNRLVEIMKFYRLSYKLEKVNNFIK--QQHQPQKKLVDSLDEKDDEELQRNKKQQNQQTQDITMQYKLEPPIDTLLYFQNQNPKT-------------------MVKHIRLSHSQK------------------QIISTAVQQYKPPQKSTTTTATDTTTTVKNDENQKQKDQLKKPIPTKEE-------------FKKPLVPTVLKDFFGRVIQTSPETKKKTMEATAGPNIKYRFQEG------------------------------------------------------------------------FTNAVKKTVYVKDFL------------------------------", "tax_id": 44689, "tax_name": "Social amoeba" }, { "uniprot_ac": "D4AC99-1", "uniprot_id": "D4AC99_RAT", "id": "D4AC99-1", "name": "Chromosome transmission fidelity protein 18 homolog", "aln": "MEDYEEDLYGVEDDFQNQFAAELEVLAELEGTGDLAPSETLQTPASRPPLTFEEAIAGGDIVPRPCPAGSSGNDSRNTRKNVRRDQPAPSSPMVKRPRLDVVKRLNFEPDKEELLYPDSPPGDITPPPSPEVFPEMWDAGPSDAGADNGLMQALPSPRNPVLRRPPVLEDYINVTSTCGERAFLVLRADLTGTGVQNHLPDVQWRGRGQLDLLGVPFTSLKEQVDNKRRQQLLEEAQQLSDTLHSLRSEGEEAMLEGPPEEEPGPGQETAQHCLWVDEFAPQHYTELLSDDFTNRCLLKWLKLWDLVVFG----------------HERPARKPRPGVEPTRVGKEAPAPGKWKSHEQVLEEMLEAELDPSR--------------RPRQKVALLCGPPGLGKTTLAHVVARHAGYCVVEMNASDDRSPEAFRTRIEAATQMESVLGAGGRPNCLVIDEIDGAP---TAAINVLLSILNRKGPQEAEQGGTAV---------------------------------------AAAGGRRRRAEGGLLTRPIICICNDQFTPSLRQLKQQALLLHVPPTLPSRLVQRLQEISLQHGMRSDPGALAALCEKTDNDIRACINTLQFLYGRGQRELS--VKDVQTTHVGLKDQRKGLFSVWQEVFQLPRAQRRLVGQDLMLPTHALLLNDSDKGSLTLASQRFYHILRVTTSAGEHEKVVQGLFDNFLRLRLRDSSLGTVCCALDWLAFDDLLEQAAHHGQSFQLLRYLPFLPAAFHVLFASSHVPRITFPSSQQEAQTRLSQTRNHIQTLVSGMAPATRSRATPQALVLDTLCLLLDVLSPK-LRPVSTQLYSAREKQQLSSLVGTMLAYSLTYHQERTPDGQYLYRLEPNVEEVCRFPELPARKPLTYQAKQLIAREIEMEKMWRAEALAWTGGGPQVDQGPSGPANLRTDSGEKGTRQPAPRNHEQRLEHIMKRAAVQEQVCCGGRGRVGLEQSDEQRVGLAPSPKEPPVAPRKWAVVSRRTPSHRPCSEASEPLTWERPGYACLSTGNLMTLFSASLRGTSLDVWSSGKWQSQAKRLRPPRRTRTSGAWVWQWAGVRCGSGSTRVSPMLFGAACTSGTCCSPTAPGHQIRLTPTGMYQGRDSWRSLFIKSHLNRECGSGSEDGTLGLLHPRVVLHQVRVQEGVLGDPVLNPLEEPVSGESQCWSFPWHLPTGV", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: . :* ..::. : . .. .* : . :. . . .. . . : . : : . : : :*. . :: : . .. : :. . ::: : .. ****:::* : :**** * :* **: ** **. :. .: . . .. : . .: : : : . * *: ** * **********: *::..* **:***::** .*:.::: . :*:*: . :*:**:****** ...:::::.:: . : .. : . :: * **:****** :.*:** *:* * : . . . ::.**: *. .*: : :* ** : * ***:*:*:***: : : : . :* ** *.*..:*:::* .. . . : : : .: : :.:*:.:* * * : .. .** : .* : . . * .. * * * * .. : : :.. : :.:* * : ::.:** :* . :* * :* :* ** * * *:*: : : . . : : . : : :* : : . * . : :. .:.: : : . . : . .: . . .: .: .:. * : : . : . . . . ::: ....* : * ::: : ", "identical_positions": 126, "similar_positions": 261, "identity": "10.39%" }, { "cls_id": "homologset.oma.817439", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VEB5-1", "uniprot_id": "SRR1L_DROME", "id": "Q9VEB5-1", "name": "SRR1-like protein", "aln": "MSNSGEDFQVVTRKKWMARKCLRRRDRHKSESDYLIDCPDVNVEKFQPRLENLCTEMCQSDYFLVAMEALQQQLEGIRKPLERIVCLGLGPFSRTYHALHQAAFVIGLHRHHKIR--EALYFDPVFRDSEKELIRLFDGCIMSKDCAGKHEAT-VPTLYYLPHCPYALMHNILWSNWKRETLPNVFLISNSFE-----MLTMTPRNQDDHITRIVEHCTETPLEDDYEHHNVFNDLSLHTFPQESLPGSNDEAFWTRCAPLKVNEDELITETETSLAALKLESE---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8V0ZTH2-1", "uniprot_id": "A0A8V0ZTH2_CHICK", "id": "A0A8V0ZTH2-1", "name": "", "aln": "MAAAG---------CWRAASGRRRRKRGEKEE-------ESGVAVLR-RLRDARDELLSSGFWAASAGAVREPLG--SGRAWRCVCYGLGRFAACPAARLQLAFLLLLLEMLEVPPRHCFLFDPAFSELELAALEALGLHLLPENEEGKHSTNGSPTLFYMVHCGKALYNNLLWRNWSVGALSNMVIIGNSFKGIEERLLTRILERDYSYIAKILKGVEEVALPAHPRYSDTFNDTSIHWFPAHKLERLSAEVWQFLEEPTYEDCDDLEIIRKGEEGSQHGPAPAQP", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :* * * . ***.* :.*. : .* :: **.: *: .*.:: .: *::: * * ** *** *: * * **:: * . :: ..: ***.* : * :. :. ::.:: ***.:. ***:*: ** ** :*:** **. :*.*:.:*.***: :** ..: .:*::*:: *..* . .: :.*** *:* ** ..* . *.: * : *:* : . .: : : ", "identical_positions": 73, "similar_positions": 89, "identity": "25.44%" }, { "cls_id": "homologset.oma.817440", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UH36-1", "uniprot_id": "SRR1L_HUMAN", "id": "Q9UH36-1", "name": "SRR1-like protein", "aln": "MAAAAAAALESWQAAAPRKR-RSAARRPRRREAAPRGREAAPRGREAAPRGPEAEFESDSGVVLRRIWEAEKDLFISDFWSSALETINRCLTKHLEQLKAPVGTLSDIFGNLHLDS-LPEESDVATDSIPREILVTGTCHLKCVCYGIGNFATCIVARNQLTFLLLLLEKCQIPRSHCWVYDPLFSQLEIEVLNTLGVTVLSENEEGKRSIRGEPTIFYMLHCGTALYNNLLWSNWSVDALSKMVIIGNSFKGLEERLLARILQKNYPYIAKILKGLEELEFPQTSQYMDIFNDTSVHWFPVQKLEQLSIDIWEFREEPDYQDCEDLEIIRNKREDPSATD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K2M3-1", "uniprot_id": "SRR1L_MOUSE", "id": "Q8K2M3-1", "name": "SRR1-like protein", "aln": "---MAAAALEPWSAVAPRRRKRAAGRRPRPGE------------------GPRAEPEADGEAVLRRLREAEEDLRISDFCSSALETITECLRKQLEQLQP----LTEALGRLHLGSSLPSAS--------QEPLASSASHVKCVCYGLGTFASCPTARIQLAFMLLFLEKCQVPRSHCWVYDPLFSQTEVSVLTSLGVTVLSENEEGKRSVQGQPTVFYMPHCGTALYNNLLWSNWSADALSRVLIIGNSFRGLEERLLARILQENYPYIAKVSDRIAGPGF-----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******.*.*.***:* *:*.**** * **.** *:*. .****: ***:** **** *******..** *:****:. *:: :*.***.* **. * :* *.:.:.*:******:*.**:* .** **:*:**:*****:************** *:.**.:***************::*:**:*** ****************.****:::******:************:*******: . : * ", "identical_positions": 170, "similar_positions": 55, "identity": "49.85%" }, { "cls_id": "homologset.oma.817465", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A3Q1LZK2-1", "uniprot_id": "A0A3Q1LZK2_BOVIN", "id": "A0A3Q1LZK2-1", "name": "", "aln": "-------------------------------------------------------MAGKKN--VLSSLAVYDEDSEAESDGEAGVETA--GSAADEKGGLVSKAYGDDDFSRLAGDEDGYEEEED--ENSKPSEDDDSETEKPEADDPKDNPEVEKRDPQELVASFSERVRNMSPDEIKIPPEPPGRCSNHLQDKIQKLYERKIKEGMDMNYIIQRKKEFRNPSIYEKLIQFCAIDELGTNYPKDMFDPHGWSEDSYYEALAKAQKIEMDKLEKAKKERTKIEFVTGTKKGTTTNATATTTTTASTAVADAQKRKSKWDSAIPVTTIAQPTILTTTATLPAVVTVTTSASGSKTTVISAVGTIVKKAKQ", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A481C7C1-1", "uniprot_id": "A0A481C7C1_PIG", "id": "A0A481C7C1-1", "name": "", "aln": "-------------------------------------------------------MAGKKN--VLSSLAVYAEDSEPESDGEAGVETA--GSAAEEKGGLVSEAYGEDDFSRLGGDEDGYEEEED--ENSKQSEDDDSETEKPEADDPKDNPEAEKRDPQELVASFSERVRNMSPDEIKIPPEPPGRCSNHLQDKIQKLYERKIKEGMDMNYIIQRKKEFRNPSIYEKLIQFCAIDELGTNYPKDMFDPHGWSEDSYYEALAKAQKIEMDKLEKAKKERTKIEFVTGTKKGTTTNATATTTTTASTAVADAQKRKSKWDSAIPVTTIAQPTILTTTATLPAVVTVTTSASGSKTTVISAVGTIVKKAKQ", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q9UHR5-1", "uniprot_id": "S30BP_HUMAN", "id": "Q9UHR5-1", "name": "SAP30-binding protein", "aln": "-------------------------------------------------------MAGKKN--VLSSLAVYAEDSEPESDGEAGIEAV--GSAAEEKGGLVSDAYGEDDFSRLGGDEDGYEEEED--ENSRQSEDDDSETEKPEADDPKDNTEAEKRDPQELVASFSERVRNMSPDEIKIPPEPPGRCSNHLQDKIQKLYERKIKEGMDMNYIIQRKKEFRNPSIYEKLIQFCAIDELGTNYPKDMFDPHGWSEDSYYEALAKAQKIEMDKLEKAKKERTKIEFVTGTKKGTTTNATSTTTTTASTAVADAQKRKSKWDSAIPVTTIAQPTILTTTATLPAVVTVTTSASGSKTTVISAVGTIVKKAKQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZZ81-1", "uniprot_id": "A0A8I5ZZ81_RAT", "id": "A0A8I5ZZ81-1", "name": "", "aln": "-------------------------------------------------------MAGKKN--VLSSLAVYAEYSDPESDGETGVDAV--GSAAEEKGGLVSDAYGEDDFSRPGGDEDGYEEEED--ENSKQSEDDDSETEKPEADDPK-----VFESPLFSTASFSEKVRNMSPDEIKIPPEPPGRCSNHLQDKIQKLYERKIKEGMDMNYIIQRKKEFRNPSS---CALWCRSDYSLTSSLQDMFDPHGWSEDSYYEALAQEMDTCLCNGLIVLSP-LQIEFVTGTKKGTTTNATATTTSTASTAVADAQKRKSKWDSAIPVTTIAQPTILTTTATLPAVVTVTTSASGSKTTVISAVGTIVKKAKQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8V1AFG1-1", "uniprot_id": "A0A8V1AFG1_CHICK", "id": "A0A8V1AFG1-1", "name": "", "aln": "MSSLSVLSAWQCASINVSPVDQRPFKAEGGGRRCYGDCSDVISARRKRSRLWQKMAAAKRS--VLSSLAVYAEDSDPESDSETGTAGSDGGTATGEKGGLVSVGYGEDDFSRLDGDEEGYEEDDD--ENSRQSEDDDSETEKPEAGDLKEFSELEKRDPQELVASFSERVRNMSPDEIRIPPEPPGRCSNHLQDKIQKLYERKIKEGMDMNYIIQRKKEFRNPSIYEKLIQFCSIDELGTNYPKDMFDPHGWSEDSYYEALAKAQKIEMDKLEKAKKERTKIEFVTGTKKGTTTSAASTTTTTASTTVGDAQKRKSKWDSAIPVTTIAQPTILTTTATLPGVVTVTTSASGSKTTVISAVGTIVKKAKQ", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "F1QJR8-1", "uniprot_id": "F1QJR8_DANRE", "id": "F1QJR8-1", "name": "", "aln": "-------------------------------------------------------MASSKKSALISSLAAYGDDSEQDSDPDT---------DDQESRGLVSASYGEDEVSRVEEAYEKPSENEDSDEDSTRNSDEEESDSGRIQDDVKEVQEVEVKDPNELVAQFSEKVRNMSPDEIRIPPEPPGRCSSHLQEKIFKLYERKLQGDFDTNSHIQKKKEFRNPSIYEKLIQFCDIDELGTNYPKDMFDPHGWSEDSYYEALAKAQKVEMDKLEKAKKEKTKIEFVTGTKKGTTTNAAALATNTTATSSTDAQKRKSKWDSAVPVT-LAQPALLTTTATLPGVVSVTTTASGTKTTVISAVGTIHKKAKQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *..:. ::****.* : *: :** :: *. **** .**:*:.** : .*::* *:* ..*::.. . .* * ..* .*.***:*********:**********.***:** ******:: .:* * **:******** :* * *. :******************: . : : . . :*************.*:: :*.*::*: ************:*** :***::********.**:***:***:*********** *****", "identical_positions": 161, "similar_positions": 69, "identity": "43.63%" }, { "cls_id": "homologset.oma.817467", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q02614-1", "uniprot_id": "S30BP_MOUSE", "id": "Q02614-1", "name": "SAP30-binding protein", "aln": "MAGKKNVLSSLAIYAEYSDPESDGETGVDAVGGATEEKGGLVSDAYGEDDFSRPGGDEDGYEEEEDENSKQSEDDDSETEKPEADDPKDNTEAEKRDPQELVASFSERVRNMSPDEIKIPPEPPGRCSNHLQDKIQKLYERKIKEGMDMNYIIQRKKEFRNPSIYEKLIQFCAIDELGTNYPKDMFDPHGWSEDSYYEALAKAQKIEMDKLEKAKKERTKIEFVTGTKKGTTTNATATSTSTASTAVADAQKRKSKWDSAIPVTTIAQPTILTTTATLPAVVTVTTSASGSKTTVISAVGTIVKKAKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3HTU4-1", "uniprot_id": "G3HTU4_CRIGR", "id": "G3HTU4-1", "name": "", "aln": "MAGKKNVLSSLAVYAEDSEPESDGEAGVDAVGGAAEEKGGLVSDAYGEDDFSRLGGDEDGYEEEEDENSKQSEDDDSETEKPEADDPKDNTEAEKRDPQELVASFSERVRNMSPDEIKIPPEPPGRCSNHLQDKIQKLYERKIKEGMDMNYIIQRKKEFRNPSIYEKLIQFCAIDELGTNYPKDMFDPHGWSEDSYYEALAKAQKIEMDKLEKAKKERTKIEFVTGTKKGTTTNATAATTTTASTAVADAQKRKSKWDSAIPVTTIAQPTILTTTATLPAVVTVTTSASGSKTTVISAVGTIVKKAKQ", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************:*** *:******:********:****************** ***************************************************************************************************************************************************************************************::*:*******************************************************************", "identical_positions": 299, "similar_positions": 7, "identity": "97.08%" }, { "cls_id": "homologset.oma.817583", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1LY69-1", "uniprot_id": "F1LY69_RAT", "id": "F1LY69-1", "name": "Intraflagellar transport protein 140 homolog", "aln": "MALYFDHRIKAPDASSSPSHITWHPTHPFLAVASVSPSSGGNVDIYLEQGEPVPDT--HIERSFQATSLCWHPTRLILAIGWETGEVIMFNKQDKEQHTVPLPHTTDIAILSWSTSGSCLVSGDKLGVLLLWRLDQRGRVQGTPLLKHEYGKPLTHCIFRLPPP---GEDLVQLAKAAVSGDEKALDMFN--WRKSSFGSFLKTGSQEGLSFFVSLMDGTVHYVDEKGKTAQVASTDSS--IQTLFYIEKREALVVVTQNLLLSLYVVNPEGEAEEVMKVKLSGKTGRRADITLIEGSLLVTAIGEPVLRFWDLERGENYILSLQE----------------------------------------KFGFEKGENINSVCYCKAKGLLAAGTHKGRVAMWKKVPVSPSGRG-AEGKDMWALQTPTELEGNITQIKWGS---RKNLLAVSTSDSVSILSEQAMSSHFHQQVAAVQISPSLVNVSFLSTGSTHSLRTDMHISGVFATKDAVAVWNGKQVAIFEP----------------------------SGSTLRNAGTFLCETSVLAMHEESIYTVEPNRLQVRTWQGTVKQLLLFSETEGSPCFLDVCGTFLVAGTDLAHFKSFDLSRREAKVHCSCKNLAQMIPDVGSITSLRCNANGNKISILLSKVDNSPDSKIYVYDVEMDTVNVFNFKTGHIGQIQTLPFNEPPTNEAHFFMNESLASYVPVNHFWDQSEPRLFVCEALQEAPGAQPQAIDKQPHMEEGTCHKEEVLILSFFASEEHGFLLHDSFPRPSTYQSLLGLEVPHYYFTKKPGEADKEDKMDSGHYHIPQMVAKKPLRDFVGLEDCDKPTRDAMLNFSFFVTIGDMDEAFKSIKLIKSETVWENMARMCVKTQRLDVAKVCLGNMGHARGARALREAEREP--ELEARVAMLAIQLGMLEEAEQLYKKCKRYDLLNKFYQASDQWQKAVEVAELHDRVHLRTTYYNYAKHLEASADCGLALSYYEKSDTHRFEVPRMLSEDLQSLELYINRMKDKTLWRWWAQYLESQAEMDTALRYYELAQDYFSLVRIHCFQGNIQKAAEIANETGDWAASYHLARQYESQDEVKQAVHFYTRAQAFNNAIRLCKENGLDDQLMNLALLSSPEDMIEAARYYEEKGEQMDRAVMLYHKAGHFSKALELAFTTQQFAALQLIAEDLDEKSDPALLARCSDFCIEHRQFEKAVELLLAAKKYHEALQLCLEQNMTITEEMAEKMTVSKDSKDLSEESRRELLEQIANCCMRQGNYHLATKKYTQAGNKLKAMRALLKSGDTEKIVFFAGVSRQKEIYIMAANYLQSLDWRKEPEIMKNIISFYTKGRALDLLAGFYDACAQVEIDEYQNYDKAHGALTEAYKCLSKAKAKNPLDQETKLAQLQSKMTLVKRFIQARRTYTE-DPKESVRQCELLLEEPDLDSTIRVGDIYGFLVEHHVQMEEYQMAYKYLEEMRKRLPSANMSYYVDQRTVDTVHQGLG------------LPPSRIMPERVRHNSMEDHKEVYEEVIEEVDNDP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PY46-1", "uniprot_id": "IF140_MOUSE", "id": "E9PY46-1", "name": "Intraflagellar transport protein 140 homolog", "aln": "MALYFDHRIKAPDTPSSPSHITWHPTHPFLAVASISPSSGGNVDIYLEQGEPVPDT--HIERSFQATSLCWHPTRLILAIGWETGEVIMFNKQDKEQHTVPLPHTTDIAILSWSTSGSCLVSGDKLGVLLLWRLDQRGRVQGTPLLKHEYGKALTHCIFRLPPP---GEDLVQLAKAAVSGDEKALDMFN--WRKSSFGSFLKTGSQEGLSFFVSLMDGTVHYVDEKGKTAQVASTDSS--IQTLFYIERREALVVVTENLLLSLYVVTPEGEAEEVMKVKLSGKTGCRADITLIEGSLLVTAIGEPVLRFWDLERGENYILSLQE----------------------------------------KFGFEKGESINCVCFCKAKGLLAAGTNKGRVAMWKKVPSFPNGRG-AEGKDMWALQTPTELEGNITQIKWGS---RKNLLAVSSTESVSILSEQAMSSHFHQQVAAVQISPSLVNVSFLSTGGTHSLHTDMHISGVFATKDAVAVWNGKQVAIFEP----------------------------SGSTLRNAGTFLCETSVLAMHEESIYTVEPNRLQVRTWQGTVKQLLLFSETEGSPCFLDVCGTFLVAGTDLAHFKSFDLSRREAKVHCSCKNLAQLVPDVGSITSLRCNANGNKISILLSKVNNSPDSKIYIYDVEMDTVNVFNFTTGQIGQIQTLPFNEPPTNETRSFMDKSLAGYTPVNHFWDQSEPRLFVCEALQEAPGAQPQAVDKQPRVEEGTCHKEEVLILSFFASEEHGFLLHDSFPRPSTYQSLLGMEVPHYYFTKKPGEADKEDRVDSGYYHIPQMVAKRPLRDFVGLEDCDKSTRDAMLNFSFFVTIGDMDEAFKSIKLIKSEAVWENMARMCVKTQRLDVAKVCLGNMGHARGARALREAEQEP--ELEARVAMLAIQLGMLEEAEQLYKKCKRYDLLNKFYQASDQWQKAVEVAELHDRVHLRTTYYNYAKHLEASADCGQALSYYEKSDTHRFEVPRMLSEDLQSLELYINRMKDKTLWRWWAQYLESQAEMDTALRYYELAQDYFSLVRIHCFQGNIQKAAEIANETGDWAASYHLARQYESQDEVKQAVHFYTRAQAFNNAIRLCKENGLDDQLMNLALLSSPEDMIEAARYYEEKGEQMDRAVMLYHKAGHFSKALELAFTTQQFAALQLIAEDLDEKSDPALLARCSDFCIEHRQFEKAVELLLAAKKYHEALQLCLEQNMTITEDMAEKMTVSKDSKDMSEESRRELLEQIANCCMRQGNYHLATKKYTQAGNKLKAMRALLKSGDTEKIVFFAGVSRQKEIYIMAANYLQSLDWRKEPEIMKSIISFYTKGRALDLLAGFYDACAQVEIDEYQNYDKAHGALTEAYKCLSKAKTKNPLDQETKLAQLQSKMTLVKRFIQARRTYTE-DPKESLRQCELLLEEPDLDSTIRVGDVYGFLVEHHVQMEEYQMAYKYLEEMRKRLPSANMSYYVDQRTVDTVHQGLGL-----------LPPSRIMPERVRHNSMEDHKEVYEEVIEEVDNDP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3HBX9-1", "uniprot_id": "G3HBX9_CRIGR", "id": "G3HBX9-1", "name": "Intraflagellar transport protein 140 homolog", "aln": "MALYFDHRIKAPDVSRSPSHITWHPTHPFLAVASVSPSCGGNVDIYLEQGEPVPDT--HIERSSRVTSLCWHPTRLILAVGWETGEVIMFNKQDKEQHTVPLPHTTDIVILSWSTSGSCLVSGDKLGVLLLWRLDQRGRVQGTPLLKHEYGKSLTHCIFRLPPP---GEDLVQLAKAAVSGDEKALDMFN--WRKSSFGSFLKTGSQEGLSFFVSLMDGTVHYVDEKGKTAQVASTDSS--IQMLFYIEKREALVVVTQNLLLSLYVVTPEGEAEEVMKVKLSGKTGRRADITLIEGTLLVTAVGEPVLRFWDLERGENYILSPQE----------------------------------------KFGFEKGENINCVCFCKTKGLLAAGTNKGRVALWKKVPNSLSGRG-VEGKDMWALQTPTELEGNITQIKWGS---RKNLLAVSSADSVSILSEQAMSSHFHQQVAAVQISPSLVNVSFLSTGSTHSLRTDMHISGVFATKDAVAVWNGKQVAVFEP----------------------------SGSTLRNAGTFLCETSVLAMHEESIYTVEPNRIQVRTWQGTVKQLLLFSESEGSPCFLDVCGTFLVAGTDLAHFKSFDLSRREAKVHCSSKNLAHMIPDVGSIMSLRCNANGNKISILLNKVDNSPDSKIYIYDVEMDTVNVFNFKTGQIGQTQTLPFNEPEMNESHIFMHERLASYIPVNHFWDQSEPRLFVCEALQEASGAQPQGVDKQPHVED-TCHKEDVLILSFFASEEHGFLLHDCFPRPPIYQSLLGMEVPHYYFTKKPGEAEKEDRVDSGHYHIPQMVAKRPLRDFVGLEDCDKPTREAMLNFSFFVTIGDMDEAFKSIKLIKSETVWENMARMCVKTQRLDVAKVCLGNMGHARGARALREAEREP--ELEARVAMLAIQLGMLEEAEELYKKCKRYDLLNKLYQASDQWQKAVEVAEVHDRVHLRTTYYNYAKHLEASADCGLALSYYEKSDTHRFEVPRMLSEDLQSLELYINRMKDKTLWRWWAQYLESQAEMDTALRYYELAQDYFSLVRIHCFQGNIQKAAEIANETGDWAASYHLARQYESQDEVKQAVHFYTRAQAFNNAIRLCKENGLDDQLMNLALLSSPEDMIEAARYYEEKGEQMDRAVMLYHKAGHFSKALELAFTTQQFAALQLIAEDLDEKSDPALLSRCSDFCIEHRQFEKAVELLLAAKKYHEALQLCLEQNMTITEEMAEKMTVSKDSKDLSEESRRELLEQIANCCMRQGNYHLATKKYTQAGNKLKAMRALLKSGDTEKIVFFAGVSRQKEIYIMAANYLQSLDWRKEPEIMKNIISFYTKGRALDLLAGFYDACAQVEIDEYQNYDKAHGALTEAYKCLSKAKAKSPLDQETKLAQLQSKMTLVKRFIQARRTYTE-DPKESIRQCELLLEEPDLDSTIRIGDVYGFLVEHHVQMEEYQMAFKYLEEMRKRIPSANISYYVDQRTVDTVHQGLG------------LPPSRILPERVRHNSMEDHKDVYEEVMEEVENDP---", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q96RY7-1", "uniprot_id": "IF140_HUMAN", "id": "Q96RY7-1", "name": "Intraflagellar transport protein 140 homolog", "aln": "MALYYDHQIEAPDAAGSPSFISWHPVHPFLAVAYISTTSTGSVDIYLEQGECVPDT--HVERPFRVASLCWHPTRLVLAVGWETGEVTVFNKQDKEQHTMPLTHTADITVLRWSPSGNCLLSGDRLGVLLLWRLDQRGRVQGTPLLKHEYGKHLTHCIFRLPPP---GEDLVQLAKAAVSGDEKALDMFN--WKKSSSGSLLKMGSHEGLLFFVSLMDGTVHYVDEKGKTTQVVSADST--IQMLFYMEKREALVVVTENLRLSLYTVPPEGKAEEVMKVKLSGKTGRRADIALIEGSLLVMAVGEAALRFWDIERGENYILSPDE----------------------------------------KFGFEKGENMNCVCYCKVKGLLAAGTDRGRVAMWRKVPDFLGSPG-AEGKDRWALQTPTELQGNITQIQWGS---RKNLLAVNSVISVAILSERAMSSHFHQQVAAMQVSPSLLNVCFLSTGVAHSLRTDMHISGVFATKDAVAVWNGRQVAIFEL----------------------------SGAAIRSAGTFLCETPVLAMHEENVYTVESNRVQVRTWQGTVKQLLLFSETEGNPCFLDICGNFLVVGTDLAHFKSFDLSRREAKAHCSCRSLAELVPGVGGIASLRCSSSGSTISILPSKADNSPDSKICFYDVEMDTVTVFDFKTGQIDRRETLSFNEQETNKSHLFVDEGLKNYVPVNHFWDQSEPRLFVCEAVQETPRSQPQSANGQP-QDGRAGPAADVLILSFFISEEHGFLLHESFPRPATSHSLLGMEVPYYYFTRKPEEADREDEVEPGCHHIPQMVSRRPLRDFVGLEDCDKATRDAMLHFSFFVTIGDMDEAFKSIKLIKSEAVWENMARMCVKTQRLDVAKVCLGNMGHARGARALREAEQEP--ELEARVAVLATQLGMLEDAEQLYRKCKRHDLLNKFYQAAGRWQEALQVAEHHDRVHLRSTYHRYAGHLEASADCSRALSYYEKSDTHRFEVPRMLSEDLPSLELYVNKMKDKTLWRWWAQYLESQGEMDAALHYYELARDHFSLVRIHCFQGNVQKAAQIANETGNLAASYHLARQYESQEEVGQAVHFYTRAQAFKNAIRLCKENGLDDQLMNLALLSSPEDMIEAARYYEEKGVQMDRAVMLYHKAGHFSKALELAFATQQFVALQLIAEDLDETSDPALLARCSDFFIEHSQYERAVELLLAARKYQEALQLCLGQNMSITEEMAEKMTVAKDSSDLPEESRRELLEQIADCCMRQGSYHLATKKYTQAGNKLKAMRALLKSGDTEKITFFASVSRQKEIYIMAANYLQSLDWRKEPEIMKNIIGFYTKGRALDLLAGFYDACAQVEIDEYQNYDKAHGALTEAYKCLAKAKAKSPLDQETRLAQLQSRMALVKRFIQARRTYTE-DPKESIKQCELLLEEPDLDSTIRIGDVYGFLVEHYVRKEEYQTAYRFLEEMRRRLPLANMSYYVSPQAVDAVHRGLG------------LPLPRTVPEQVRHNSMEDARELDEEVVEEADDDP---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1B860-1", "uniprot_id": "E1B860_BOVIN", "id": "E1B860-1", "name": "Intraflagellar transport protein 140 homolog", "aln": "MALYFDHRIEAPDTVGSPSHIGWHPIYPFLAVASVSTTSGGSVDVYLEQGERVPDM--HVERSFRVTCLCWHPTRLILAIGWESGEVVMFNKQDKEQHAVPATHTADIAILAWSPNGNCLVSGDRLGVLLLWRLDQRGRVQGMPLLRHEYGQPLTHCIFLLPPP---GEDLVQLARAAVSGDEKALDMFN--WKKSGFRSILKMGSQEGLSFFVSLTDGTVHHVDEKGRTAQVASTDSS--IQTLFYLEQRGALVAVTDSLLLCLFTVTPEGTAEEVMKVKLSGKTGHRADIALIDGSLLVTAIGEAALRFWDLERGENYVLSPEE----------------------------------------KFGFEKGENINCVSYCKVKGLLAAGTDKGRVAMWRKAPGLPNGRG-AEGKDKWTLQAPTELEGNIMQIKWGS---RKSLLAVNSISSVLILHEQAMSSHFHQQVAAVQVSPSLLSVSFLSTGVTHSLRTDMHVSGVFATKDAVAVWNGKQVVIFEP----------------------------SGATLRSAGSFLCESPVLAMHEENVYTVEPNRVQVRTWQGTVKQLLPFSESEGNPCFLDICGTFLVVGTDLAHFKSFDLSRREAKVHCGCKSLAELVPGVGGLTSLRCSASGSKISLLLSKADNSPDSKICFYDVDMDTVTILDLKTGQIDQRETLSINGQETKKSQALEDERLTDLVPVSHFWDQSEPRLFVCEAVREVPGAPP------QPADRNALAEADVVVLSFFVSEEHGFLLQDSFPRPPAFQTLLGIQVPHYYFTRKPGEANLEDQLDSGSQCIPQAVGRRPLRDFVGLEDCDKPTRDAMINFSFFLTIGDMDEAFRSIKLIKSQAVWENMARMCVKTQRLDVARVCLGHMGHARGARALREAQREP--EPEARVAMLAVQLGMLEDAEQLYRRCGRYDLLNRLLQASGQWQRAIEVAERHDRMHLRTTYYNYARHLEASGDCSPALSYYEKSDTHRFEVPRMLVEDLQALGLYVNKMKDKTLWRWWAQYLESQAKMDAALHYYELAQDYFSLVRIHCFQGNIQRAAEIASETGNWAASYHLARQYESQNEVRQAVHFYTRAQAFNNAIRLCKEHGLDDQLMNLALLSSPEDMLEAARYYEERGEQMDRAVMLYHKAGHFSKALELAFATQQFAALQLVAEDLDEKSDPVLLARCSDFFLEHGQCEKAVELLLAAKKYQEALQLCLEQNLTITEEMAEKMTVPKDCKELSEEARRVLLEQIASCCMRQGSYHLATKKYTQAGDRLKAMRALLKSGDTEKIVFFAGVSRQKEIYVMAANYLQSLDWRKDPEVMKSIISFYTKGRALDLLAGFYDACAQVEVDEYQNYDKAHGALTEAYKCLSKAKARSPLDQEARLAQLQSRMTLVKRFMQARRTYTE-DPKGSVRQCQLLLEEPHLDSGVRVGDVYGFLVERHVHSGDLQTAYRYLEEMRQRLPSANVSYYVSQHTVDAVHQGLG------------LPLTCAAPKRAQHSSMEEHKEADEEVAEEVESGP---", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1RG13-1", "uniprot_id": "F1RG13_PIG", "id": "F1RG13-1", "name": "Intraflagellar transport protein 140 homolog", "aln": "MLLYFDHRVEAPDAAGSPSHVCWHPVHPFLAVASVNPALGGSVDIYLEQGECVPNT--HMERASRVTILSWHPTRPVLAVGWETGEAVIFNKQDKEQHAVPPTHTADLTVLTWSPSGNYLASGDRLGVLILWRLDQRGRVQGAPLLKHDYGQPLTHCIFRRPPP---GEDLVQLAKAAVSGDEKALDMFN--WSKSGLGSVLKMGSQEGLSFFVSLTDGTVHHVDEEGKTAWAVATDSC--VQALFYVDKRQALVAVTESLLLCLFTVTPEGEAAEVLKVKLSGKTGRRADVALIEGSLLVSATGEAVLRFWDLDRGENYLLSPEE----------------------------------------KFGFEKGENINCVSYCEVKGLLAAGTDRGRVATWRKVPSAPSGHG-LEGKDRWTLHAPAELPGSITQIKWGS---RKSLLAVTSSSSVVVLREQAVSSHFHQQVAVVQVSPRLLSVSCLSAGTTHYLHTDMHVSGVFATKDAVAVWNGKQVVIFEA----------------------------SGAVFRSAGSFLCESPVLAMHEESVYTVEPNRVQVRTWQGTVKQLLLFSETEGNPCFLDVCGNFLVVGTDLAHFKSFDLSRREAKLHCCGKSLAELVPGAGGMVSLRCSASGSKISILLSKADHSPDSKICFYDVDTDTVSVLDLKTGQADGIEAS--TGQET-KSQALGDERLTDLVPVSHFWDQSEPRLFVCEAVREAPDADRR-----APAER---PPADVLVLAFFVTEEHGFLLQESFPRPPAFQTLLGVQVPYYYFTRKPGEADRETRVDGGSQPGPQMVGRWPLRDFVGLEDCDKATRDAMLNFSVFLTVGDMDEAFRSIRLIKSEAVWENMARMCVKTQRLDVAKVCLGHMGHARGARALREAEREP--ELEARVAVLAIQLGMLEEAEQLYKKCGRYDLLNRLLQASGQWQRAIEVAERHDRVHLRTTYYNYARHLEANADYSLALSYYEKSDTHRFEVPRMLAEDLQFLERYVNTMKDRTLWRWWAQYLESQAEMDAALHYYGLAQDYFSLVRIHCFQGNIQKAAEIASETGNWAASYHLARQYESQEEVGQAVHFYTRAQAFNNAIRLCKEHGLDDQLMNLALLSSPEDMIEAARYYEEKGEQADRAVVLYHKAGHLSKALELAFATQQFVALQLVAEDLDEKSDPALLTRCSDFFLEHQQYEKAVELLLAARKYQEALQLCLEQNLTITEEMAEKMTVAKDCADLSEESRRELLEQVASCCMRQGSYHLAAKKYTQAGDRLKAMRALLKSGDTEKIVFFAGVSRQKEVYVMAANYLQSLDWRRDPEIMKNIISFYTRGRAPELLAGFYDACAQVEVDEYQNYDKAHGALTEAYKCLAKAKARSPLDHEARLAQLQSRMTLVKRFMQARRMYAE-DPEEALRQGQLLLEELGPDSTVRLGDVCGFLVEGHVQAGDLRTAYRYLEEMQKRLPSARLSYYVSQRALDAVHQGLG------------VPAMCHG--------NAEDKDMDEEVVEEVEGGP---", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A8V0Z0L4-1", "uniprot_id": "A0A8V0Z0L4_CHICK", "id": "A0A8V0Z0L4-1", "name": "Intraflagellar transport protein 140 homolog", "aln": "MAVYVDHRTEAPDSVASPSLITWHSVHPLLAVASISTASGGCVDIYLEQGEHEPDA--HIERSFQVTSLSWHPSRLILAAGWETGEVVILNKQDKELHTVPPNHNAKITILNWSSNGSRLVSGDRHGILFLWRMDQRGRVQGPPMLKHEYGKCLSHCIFRPPPP---GEDFLQLAKAAVSGDEKALDMFN--WRKAGTEAPLKMGLQEGLSFFITLTDGSVHYVNEKGKTSHVLSADNL--VQKLLFMEKRDALVVVTENLLLSLHTITLEGDAKELMKVKLGGKTGNSADIILIDHSLIVTAMGETVLRFWDLDRGENYVLSPDV----------------------------------------QFGFEAGECMNCVSYCSAKGLLAAGTNKGRVAMWRSVSVSSQSTGALEGKEKWKLQASTELEGNITQIKWGS---RKNLLAVNSISSVVILSEQAMSCHYNQQVAAVQVSPSLFNVTFFSTGTTHNLHVDMTVNGVFTTKDAVVFWNGKQVTVFEC----------------------------SEDTLRNAGSFLCDSPVLSMHGENLYTVEPHRVQVRTWQGTVKQLLVFSEAEGNPCLLDVCGNFLAVGTDLAHFKIFDLSRREAKVHCNSKNFSELFPGLGNIASVKCNANGNKVSILVSKANGSTDSKICFYDVEMDKVTLFDFKAERGIGREKLS--SGHGIDRSVVEYPDLHNHIPVCHFWDCSEPRLFVCETIPETGVRSP------SQKNNQTESMLDVWVVSFFSTEEHGLLLQDSFPLPSLYEVLLGIDVPHYYFAKKPGETGK-GQAESGSK-VLQMASRQPMRDFIGLGDCDKATRDAMLNFSFYLTAGDMDEAFKSIKLIKSEAVWENMARMCVKTQRLDVAKICLGNMGHARGARALREAEQEP--EQEARVAVLAVQLGMLEDAERLYKACKRYDLLNKFYQATNQWQKAIETAEAHDRVHLRTTYYNYAKHLEAVGDHALALSHYEKSDTHRFEVPRMLSEDLQALENYVNKMKDKSLWKWWAQYLESQSDLESALKYYALAQDYFSLVRVHCFQGNIQKAAEIANETGNWAASYHLARQYESQDEIKQAVHFYTRAQAFNNAIRLCKENNLDDQLMNLALLSSPEDMIEAACYYEEKGEQMDRAVMLYHKAGHFSKALELAFATQQFGALQLIAEDLDEKSDPALLARCSGFFIEHAQYEKAVELLLTAKKYHEALQLCLKQNLTITEEMAERMTVSKDSKDLSEESRRELLEQIADCCMRQGNYHMATKKYTQAGNKLKAMKALLRSGDTEKIVFFAGVSRQREIYIMAANYLQSLDWRKDPEIMKNIISFYTKGRALDLLAGFYDVCAQVEIDEYQNYEKAQGALTEAYKCLSKAKTKSPLEQESKLAHLQSKMALIKRFIHARRVYSE-DPKEAVRQCELLLAEQDLDNTIRQGDVLGFLVEHYLQVEEFHMAYQYLEQMRKRIPCTNLTYYIKQQTIEAVHRGAG------------IPISQALVPERSQHSSVENKDVEEEVADEVEGP----", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q7KTZ4-1", "uniprot_id": "Q7KTZ4_DROME", "id": "Q7KTZ4-1", "name": "", "aln": "MTLYFDTKIEFLDSDAVSTISSWHPSEPLFAVASFSPERGGSVTIFADTGEPQRDVTYPVHATSQATALCWHPEKALLASGWEHGDIHVWFAGHREFASVNAPHKAAIVLLQFSEQGGRMVTADAMGLVTGWRCD--GQYQFLTMFSHDLREVLLLICFRLTVESEVREEMANLAKAAVAGDENALDTLTNWRPRTAARSMTHSGVRDNHCFYACTQGGVVYYINQGGACVEVMKCGSLPPIVQMLWHPRKDAVICLMEDLTVTLFLVESTGILTELDRVKMSGRGGGRQGGIAWSGNSLAIITGDFFVRIWDIERSDNYLLKMDLPSGNQPGSSMTTLSNGTMSSSNQFFSHDSSESSGVLRKTPKYGQLNGEMFTCLAYSSTGQTLCAGTSQGNVYTWKRSGSRLVGAP----EDAWQLTNISSVRGAIRSCEWGYNELAKPCMLVNCLSNVFMLKEQPLLAVHTRELWAVQRSAKSVQLTHCS-GREAIVQSEFAVTAMALSELSLVMSNGRSISSYSLQKVEKSLDEFEEILQTVEGTTPTTESTTTPLSLKLLQTFAAECLALNLCNQNIFCLGSSDVFVYSVGGVVLHRIQASDIEGKIIGMDLSGCYLSVFTMNGYVKAYDVSRHDPKLLFPSKSGHDIFDDFGEFILVKCNSSGSHLAMVIASSNFTPISTLFCWDFERSNLLEYGLLEPETN------------------AKKESSTSLPVRIFWDAEEPRLLATEVKSMIQKTLPQ------KNSLQPSHFVQSKVVLLFYSEKGCLNVLETQSMSPGCQLLN-LCVPNVIRLKIN------------------TMEEQPLQDFVDLQQCNPVTRKQVLNFSLYVAEGNMDMAYRSIRSIQSKVIWTNLAKMCVHTNRLDVAKVCMGHLEQARSVRALRQAIEDDDLETEAKVAVLAIELGMIEEAKDLYRRCKRFDLLNKLLQSIGHLDEAVELAEAEDRIHLKHTYYQKAQELRERGDIKGALEYFEKTQNPAQNITQLLLENPGAMKRYIQTTSDPKLLKWWGQYIESSGDMDAALAVYHKAEDWFSQVKILCYLGKISKADAIARQSGDRAACYHLARHYENVGKFQEAIMFFTRAQTFSNAIRICKENDFQEELWTVASSSRQRDKAIAAAYFEECG-NFKHAVELYHRAGMLHKALEMAFESQQPEILEIIASDLAPDSDAELINRCADFFCSIEQFQKAVHLLAKTRHLERALGICSEKGVPVTEELSEMLTPEKG--EFEEATRVHILVQLGEFLQQQGDYHSATKKFTQAGDKIRAMKSLLKSGNTDKIIFFANMSRQREVYIMAANYLQALDWQSDPQVLKHIVTFYTKGQAFDSLANFYAICAQIEIEEFQDYGKALTAMQEASKCLEKLSHAQHVYN-----NLQRTVADVKAILEIQQALREGDHQLVIGSCRSMLIKPELP-PIRHAHILAMLIRALVYVKDYSEAGRALKELTVKDSTWSASGLLDRSIVHKIAQECHLEFDLIWNAGRQVTASTSGTAATGMSSTSGMTTTDDDDADDEEITEELH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :* * : : * .: **. *::*** ... * * :: : ** : :. . :.: *.*** : :** *** *: : .:* :: *.: :.:* :* .*. : :.* *:: ** * *: * .:: *: : * * . *:: :**:***:***:*** :. ::. : : * ::. *: .* *::::: * . .. : ::: :: *:: : :.* : *. : * *: :**:.*: * . . . :. *: :*:**::*.:**:*. : ::* ** :..:.:... *.*** :*.* *: . :: * * :.: * * . :** * : *. .* :* *:.: . . ::: .:* *. ..: * * :: :: :..: :: ::.. **:.: :. : :: :* .: .* : :.:: : . : * : *.* : : *: **. :*:.* :* . * .:.* :*:**::.* :. .:. . * : ::*.:.*. :::: . : :. *.: :*.: ..: .: . ** *** .****:. *. . : :: :* :*: : : : . .. . * : ** : . *::**:.* :*: **. :::**.::: *:** *::**: *:*:.:* *:*:***:*:*****::*:*:: :**..****:* .: * **:**:** :***:*:*: **: * *.****:: *: .: :.*:: ** .**:**: **:. * .*. .* **.::**::. ::.::* *: : *:: .* .* :**.**:**...:::** * *.* ** *:: *: *::.:* ** ::*: **.*****:**. :. :*: *:****:*.****:***:.::::* .:* * .* ** *:** * : .:** ***:** : ****:** :** *:::*.** **. *: **:.* . * ::**.** ::: ..** :* :.:.:**:::* :* *. :: * :* :* *:.. :**.** *:**:****::::**::**:**:*:** ***.:***:*:*:*******:***: :*:::* *: ***:*:* : **.** ***:*::*:*:* ** *: ** *** * . . : : :** :: :* ::. :: * * : : . . :* : :* ..: .:*:. : : * : *::: : . : :. :. : : :. :: :: : ", "identical_positions": 388, "similar_positions": 503, "identity": "24.84%" }, { "cls_id": "homologset.oma.817601", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BSC4-1", "uniprot_id": "NOL10_HUMAN", "id": "Q9BSC4-1", "name": "Nucleolar protein 10", "aln": "-------MQVSSLNEVKIYSLS---CGKSLPEWLSDRKKRALQKKDVDVRRRIELIQDFEMPTVCTTIKVSKDGQYILATGTYKPRVRCYDTYQLSLKFERCLDSEVVTFEILSDDYSKIVFLHNDRYIEFHSQSGFYYKTRIPKFGRDFSYHYPSCDLYFVGASSEVYRLNLEQGRYLNPLQTDAAE-NNVCDINSVHGLFATGTIEGRVECWDPRTRNRVGLLDCALNSVTADSEINSLP--TISALKFN--GALTMAVGTTTGQVLLYDLRSDKPLLVKDHQYGLPIKSVHFQDSLD----LILSADSRIVKMWNKNSGKIFTSLEPEHD-LNDVCLYPNSGMLLTANETPKMGIYYIPVLGPAPRWCSFLDNLTEELEENPESTVYDDYKFVTKKDLENLGLTHLIGSPFLRAYMHGFFMDIRLYHKVKLMVNPFAYEEYRKDKIRQKIEETRAQRVQLK-----------KLPKVNKELALKLIEE-----------EEEKQKSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNP--LVSKISEKRKKKLR---------LLEQQEL-REKEEE--------EEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQ-ERLKEDQQ-------TVLKPQFYEIKA-----GEEFRS------FKDSATKQKLMNKTLEDRLKIEAKNG-TLSVSDTTVGSKQLTFTLKRSE----QQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGRSFH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1BKR4-1", "uniprot_id": "E1BKR4_BOVIN", "id": "E1BKR4-1", "name": "Nucleolar protein 10", "aln": "-------MQVSSLNEVKIYSLS---CGKSLPEWLSDRKKRALQKKDVDVRRRIELIQDFEMPTVCTTIKVSKDGQYILATGTYKPRVRCYDTYQLSLKFERCLDSEVVTFETLSDDYSKIVFLHNDRYIEFHSQSGFYYKTRIPKFGRDFSYHYPSCDLYFVGASSEVYRLNLEQGRYLNPLQTDAAE-NNVCDINSVHGLFATGTIEGRVECWDPRTRGRVGVLDCALSSVTADSEINSLP--TISALKFN--GALTMAVGTSTGQVLLYDLRSDKPLLVKDHQYGLPIKSVHFQDSLD----LILSADSRIIKMWNKNSGKIFTSLEPEHD-LNDVCLYPSSGMLLTANEAPKMGIYYIPVLGPAPRWCSFLDNLTEELEENPESTVYDDYKFVTKKDLENLGLTHLIGSPFLRAYMHGFFMDIRLYHKVKLMLNPFAYEEYRKDKIRQKIEETRAQRVQLK-----------KLPKVNKELALKLIEE-----------EEEKQKSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNP--LVSKISEKRKKKLR---------LLEQQEL-HGKEEE--------EEPEGKPSDAESSESSDDEKDWVAEVRKQRRLLQQEEKVKRQ-EQLREDQQ-------TVLKPQFYEIKA-----GEEFRS------FKDSATKQKLMNKTLEDRLKLEAKNG-TLSVSDTTVGSKQLTFTLKKSE----QQKKQQEAEKLHRQERKAVRRSAGHLRSRPRRGRPFH--", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q66H99-1", "uniprot_id": "NOL10_RAT", "id": "Q66H99-1", "name": "Nucleolar protein 10", "aln": "-------MQVSSLNEVKIYSLS---CGKSLPEWLSDRKKRALQKKDVDVRRRIELIQDFEMPTVCTTIKVSKDGQYILATGTYKPRVRCYDTYQLSLKFERCLDSEVVTFEILSDDYSKIVFLHNDRYIEFHSQSGFYYKTRIPKFGRDFSYHYPSCDLYFVGASSEVYRLNLEQGRYLNPLQTDAAE-NNVCDINTVHGLFATGTIEGRVECWDPRVRKRVGVLDCALNSVTADSEINSLP--TISALKFN--GALSMAVGTSTGQVLLYDLRSDKPLLVKDHQYGLPIKSVHFQDSLD----LVLSADSRIVKMWNKDSGKIFTSLEPEHD-LNDVCLYPSSGMILTANESPKMGIYYIPVLGPAPRWCSFLDNLTEELEENPESTVYDDYKFVTKKDLENLGLTHLIGSPFLRAYMHGFFMDIRLYHKVKLMVNPFAYEEYRKDKIRQKIEETRAQRVQLK-----------KLPKVNKELALKLIEE-----------EEEKQKSTLKKKVKSLPNILTDDRFKVMFENPDFQVDEDSEEFRLLNP--LVSRISEKRKKQLR---------LLEQQEQ-LKNEEE--------EEPEGKPSDAESSESSDDEKDWVEEVRKQRRLLQQEERVKRQ-EQLKEDQQ-------TVLKPQFYEIKA-----GEEFRS------FKESATKQKLMNKTLEDRLKLEAKHG-TLSVSDTTVGSKQLTFTLKRSE----QQKKQQEAEKLHRQERKKLRRSASHLRSRPRRGRPFH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5RJG1-1", "uniprot_id": "NOL10_MOUSE", "id": "Q5RJG1-1", "name": "Nucleolar protein 10", "aln": "-------MQVSSLNEVKIYSLS---CGKSLPEWLSDRKKRALQKKNVDVRRRIELIQDFEMPTVCTTIKVSKDGQYILATGTYKPRVRCYDTYQLSLKFERCLDSEVVTFEILSDDYSKIVFLHNDRYIEFHSQSGFYYKTRIPKFGRDFSYHYPSCDLYFVGASSEVYRLNLEQGRYLNPLQTDAAE-NNVCDINAVHGLFATGTIEGRVECWDPRVRKRVGVLDCALNSVTADSEINSLP--TISALKFN--GALSMAVGTSTGQVLLYDLRSDKPLLVKDHQYGLPIKSVHFQDSLD----LVLSADSRIVKMWNKDSGKIFTSLEPEHD-LNDVCLYPSSGMLLTANESPKMGIYYIPVLGPAPRWCSFLDNLTEELEENPESTVYDDYKFVTKKDLENLGLTHLIGSPFLRAYMHGFFMDIRLYHKVKLMVNPFAYEEYRKDKIRQKIEETRAQRVQLK-----------KLPKVNKELALKLIEE-----------EEEKQKSTLKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNP--LVSRISEKRKKQLR---------LLEQQE--LKDEEE--------EEPEGKPSDAESSESSDDEKGWVEEVRKQRRLLQQEERVKRQ-EQLKEDQQ-------TVLKPQFYEIKA-----GEEFRS------FKESATKQRLMNKTLEDRLKLEAKHG-TLNVSDTTVGSKQLTFTLKRSE----QQKKQQEAEKLHRQERKNLRRSASHLRSRPRRGRPFH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3HB02-1", "uniprot_id": "G3HB02_CRIGR", "id": "G3HB02-1", "name": "Nucleolar protein 10", "aln": "-------MQVSSLNEVKIYSLS---CGKSLPEWLSDRKKRALQKKDVDVRRRIELIQDFEMPTVCTTIKVSKDGQYILATGTYKPRVRCYDTYQLSLKFERCLDSEVVTFEILSDDYSKIVFLHNDRYIEFHSQSGFYYKTRIPKFGRDFSYHYPSCDLYFVGASSEVYRLNLEQGRYLNPLQTDAAE-NNVCDINAVHGLFATGTIEGRVECWDPRVRKRVGVLDCALNSVTADSEINSLP--TISALKFN--GALTMAVGTSTGQVLLYDLRSDKPLLVKDHQYGLPIKSVHFQDSLD----LVLSSDSRIVKMWNRNSGKIFTSLEPEHD-LNDVCLYPNSGMLLTANEAPKMGIYYIPVLGPAPRWCSFLDNLTEELEENPESTVYDDYKFVTKKDLENLGLTHLIGSPFLRAYMHGFFMDIRLYHKVKLMVNPFAYEEYRKDKIRQKIEETRAQRVQLK-----------KLPKVNKELALKLIEE-----------EEEKQKATLKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNP--LVSRISEKRKKQLR---------LLEQQELQAKNEEE--------EEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEERAQRRREQLEEDQE-------TVLKPQFYEIKA-----GEEFRS------FKESATKQRLMNKTLEDRLKLEAKHG-TLNVSDTTVGSKQLTFTLKRSE----QQKKQQEAEKLHRQERKKLRRSAGHLRSRPRRGRPFH--", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "E1BXP3-1", "uniprot_id": "E1BXP3_CHICK", "id": "E1BXP3-1", "name": "Nucleolar protein 10", "aln": "-------MQVSSLNEVKIYSLS---AGRSLPEWLSDRKKRALQKKDVDIRRRIELIQDFEMPTVSTKIKVSRDGQYIMAVGTYKPRIRCYDTYQLSQKFERCLDSEVVTFEILSDDYSKIVFLQCDRYVEFHSQHGHYYRTRIPKFGRDFSYHYPSCDLYFVGASSEVYRLNLEQGRFLNSLPTDASE-NNVCDINPVHYLFATGTAEGKVECWDPRTRNRVGLLDCALSSVTADTEVDCLP--SISALKFD--GALNMAVGTSTGQVLLYDLRSSNPLIVKDHQYGLPIKSIQFQHQLD----LIISADSRIIKMWNKDTGKIFTSMEPEYD-INDVCLYPNSGMLMTANEAPRMNIYYMPVLGPAPKWCSFLDNLTEELEENPESTVYDDYKFVTRKDLENLGLAHLIGSSLLRAYMHGFFMDIRLYHKAKMMANPFAYEEYRREKIRQKIEETRAQRVQLK-----------KLPKVNKELALKLIEE-----------EGEEQQATRKRKQKNLPSLLKDDRFKVMFENPDFQVDEQSEEFRLLNP--LVSKISEKRKKKLK---------LLQEQEA-REQEEE--------EEPEGKPSDAESSESSDDEKGWVEEVRKQRKLLRQEEKVKRQ-ERFKEDQQ-------TLLKPQFFEIKE-----GEEFRS------FKDSAKKQKLMKKTLGDRLKLEEKLG-TLNVSDTTVGSKQATFKLKKSE----HQKKQQEAEKQHRQERKALRRSASHLKSKHGRGQRFH--", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9V3P2-1", "uniprot_id": "Q9V3P2_DROME", "id": "Q9V3P2-1", "name": "Nucleolar protein 10", "aln": "-------MFVNEVNDVKIYNLS---AGKSVPDWLTDRRKRSQLMKKVDSRRQIELIQDFDMPGVCTSIRMSPDQQYILATGTYKPRVKCFEVSNLSIKFERCFDAEVTTFEVISDDYSKMVFLQCDRYVEIHAAHGRHYRLRIPRFGRDMKYHKPSCDMFIVGVGRDIFRLNLERGQFLQPFETDGSC-LNACEVNPEHHLLVAGTKEGTVEAWDPRTKQRCSTLDVAMKLP----GVKEFP--SVTALKFR--NGLHMGVGTASGHVLIYDIRAKQPLLVKNHLNRLPIKRLAFNPAQN----AVYSLDEATLKLWDEQTGKQIAYVESTSS-FNDFCTIPDTGMFFVAQEDVKMMTYYVPAMGPAPRWCSFLDNLTEEIESEVVENVYDDYQFVTAKELAELGMEHLVGSNLLKGYMHGYFMDARLYNKAKAVVEPFAFDRFRKDKIRQEIESERKSRLQIES----------KLPKVNKELALKIMDE-----------QANPSNS---AKQRNVPSLLEDSRFKAMFENADFEVNKSAEEYRLLAP--VLNRLDKSKAKELKKRVEVAHVAELHADEAQQREESDNDEDLFGFEKSDGETKDDSGDEASSDDDDRREYVKEMKQAYKQVKRQREEEEELEDDEQQPDEISDTAKRPQTNGHSQQPTTNGNRFTMTPLDQHQGSSLLQQRIKKASLQDRVRVMSQLEGQVTNVGRSLGNRQMTFEVNKQKKSQFHAKKREAEMKKHREERRSIVRPIKSLRLKKVN---FK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q54D60-1", "uniprot_id": "Q54D60_DICDI", "id": "Q54D60-1", "name": "", "aln": "-------MNLLTTNGVKIYNVS---AGKSLPEWLSE-NKREELRKNKEFNQRIELIQDFSFETSSQRVRISQDGQYIMATGIYPPQFKVFELSQLSQKVSRNLDCNVVTFEMLSDDYSKPVFLRDDRYIEFHAKFGSYFKTRIPKLGRDMTYHKPSCDLYITASDTEVYRLNLEEGRFLAPLTTHLNGGINVIAQNPVHQLMMLGGENGFIECWDPRVRTMVSTINAAAALPDYNSADEDSEPISITAGKFGP-DGLLLGLGTSNGGVLMYDIRSASPSMIKMHQYQLPINSINFHISGDGTQ-RIMSSDAKIFKSFEKDTGKIHMVLEPKNP-ITDVVVTNGSGLLLMPGNTQKIQTYYVPALGAAPRWCSFLDNLTEELEED-KQLVYEDYKFITRDEVAKLDIENLIGTGYLKAYMHGYFIHIKLYNKVVMSKNPTNYEDLRKQQIKDKLAEKNQTRISLTKKPTSSSSTTINKPAVNAKLAERLAAQY----------EIQKQDSHKPMDAEITQSSSSDPRFKAMFENRDFEQDEGSEAFLRVNPRSKISKLDKHIQDNFDK-------VDFDDEDSDDDNDDDDDD-----QDNYKNKNRNSDSEDSDDDDDYDEDDIKIKSNPITNKRKELQKEQIKSKKP-----------IKMYEIKT-----GHSLPSLN----GKESGKQQILKSAPFSVRVGKEIKKATGLDDKDEKDGTK-----ITKKD------NGDLEIAFIPSASKKNLNNKSKKVVKKK---------", "tax_id": 44689, "tax_name": "Social amoeba" }, { "uniprot_ac": "P48234-1", "uniprot_id": "NOL10_YEAST", "id": "P48234-1", "name": "Ribosome biogenesis protein ENP2", "aln": "-----MVLKSTSANDVSVYQVSGTNVSRSLPDWIAKKRKRQ-LKNDLEYQNRVELIQDFEFSEASNKIKVSRDGQYCMATGTYKPQIHVYDFANLSLKFDRHTDAENVDFTILSDDWTKSVHLQNDRSIQFQNKGGLHYTTRIPKFGRSLVYNKVNCDLYVGASGNELYRLNLEKGRFLNPFKLDTEG-VNHVSINEVNGLLAAGTETNVVEFWDPRSRSRVSKLYLENNID-------NRP-FQVTTTSFRN-DGLTFACGTSNGYSYIYDLRTSEPSIIKDQGYGFDIKKIIWLDNVGTEN-KIVTCDKRIAKIWDRLDGKAYASMEPSVD-INDIEHVPGTGMFFTANESIPMHTYYIPSLGPSPRWCSFLDSITEELEEKPSDTVYSNYRFITRDDVKKLNLTHLVGSRVLRAYMHGFFINTELYDKVSLIANPDAYKDEREREIRRRIEKERESRIRSSG------AVQKPKIKVNKTLVDKLSQK---------------------RGDKVAGKVLTDDRFKEMFEDEEFQVDEDDYDFKQLNPVKSIKETEEGAAKRIR-----ALTAAEESDEERIAMKDGRGHYDYEDEESDEEESDDETNQKSNKEELSEKDLRKMEKQKALIERRKKEKEQSERFMN--------EMKAGTSTSTQR----DESAHVTFG--EQVGELLEVENGKKSNESILRRNQRGEAELTFIPQRKSKKDGNYKSRRHD-----NSSDEEGIDENGNKKDNGRSKPRFENRRRASKNAFRGM", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9M1J9-1", "uniprot_id": "Q9M1J9_ARATH", "id": "Q9M1J9-1", "name": "", "aln": "MTSYGDRLKSTSINGVKLYNVS---SAPNVPTWLNPKKQRALRKNP-HYMQRVELIQELKFETATTRIKATPDGEYLIASGIYPPQVKVYELNQLALKFERHLDSEIVDFEILDDDFSKLAFLCADRSINLHAKYGKHHTLRIPRMGRDMTYDSWSCDLLCAASSPDLYRINLEQGRFLSPLSTQSPA-LNVVSRSNLHGLVACGGEDGAVEFFDMRMKSSAARINAVTHGG--------DAAAEVTAIEFDDSEGLQVAVGSSAGKVFIYDLRTSTPIRVKDHMYESPILNIKWQRTLNTQQPKLITTDKHIVRIWDPNTGEGMTSIEPTQGGINDICVFRGSGLMLLALDSSLIPSYFIPELGPAPKWCSPLENLTEELEESAQTTIYDNYKFLAMEDLEKLQLTHLIGTDLLKASMHGYFINYHLYKKALAVIEPFAFDDYLERRKQEKLEEQRTQRITKKR----------RLPKVNRDLAARLHGDESEEENKTAEDGEATKKVLKKKKPILTDEHFVDGRFGSMFQNPDFQIDKDSYEYGVLHPVASSKKQPSLLDEHFE---------AVSDDDENSDSDAS--------QPSDDEADDGDATRPSKKARTPKLYEVKDERHAAAYHNRTSLAKEDSLPMG---------ERVKAIENRRGNFGGSKDIKFG-------PGGSREFSFKARGSSKYKEDRDDEYEDGQRNKRRGVQSLGLKSTNIRGGFRGRGGGGFRGRGGGGSRGKGGRGGGRGRGRQ---------", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * *.:*.:* . .:* *: .:* : . .::****::.: :: : * :* :* * * *:.: :: :*: *..* *.: . * :.**::* ..* ** :::: * :. ***::**.: *. .**: . . :::*:***.*::* .: . * . : *. * . :* :* * : . : ::: .* .* .. *:: * :**:*: * :* : * : : . : : * : :: *: :*. :.*. .:*::: . : : *::* :*.:*:*** *:.:***:*.. :*.:*:*:: .:: :* : :*:*: *:. ***:*:. .**.*. :* :. . . : .: . . *: ** *. :: . . * ** **:: :*: :: : : * .. . ..: :: . : : . . . *.. : . .. :. .. . . . : . .: : ", "identical_positions": 103, "similar_positions": 203, "identity": "13.27%" }, { "cls_id": "homologset.oma.817617", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K9D9-1", "uniprot_id": "A0A0G2K9D9_RAT", "id": "A0A0G2K9D9-1", "name": "", "aln": "MNPEEEKANIISEDFTGDGVDTEAGRQKKNLKVQKKQKKKRPPTTPPEEMVSDKFQDGGQQEMVEEEPETNLLSLPARRGPRSLPPIPSASRTGFVEFSMRERMREKLQAARSKAESALLRDVPTPRPRRLRSP-RERETETEFGTEPSTEVQGTQQEDDTRSYSRIKLRDSVQKIKSKPQPPPGFPSAEEAYNFFTFNFDPEPEEPEEKTPVKGGDGAHQEEQEGEEG-THTQEREKKMEEEELLDGKDAEDFLLGLDPTAHDFVAVRAAEYKSAHLQLQKEKEILFTPSRLTVPTYKKLPENIQPRFLEDEGLYTGARPEVARTNENIMENRLLIQEPERKWFGDDGRILALPSPIKPFPSRPSLSTQERSPKAELETLYKKAEKYVHSRQHMIASGEPPGNFQLDIDISGLIFTHHPCFSREHVLASKLAQLYDQFLARQQRNKTKFLTDKLQALRRAVETSLNPEKPHQSLDTTQKTINEYKSEIRQTRKLRDAEQEKDRTLLKTIIKVWKEMKSLREFQRFTNTPLKLVLRKERVDQKLDEEVYEAEIQAEIRELLEEHMEEYALKMEEYRASRQHWKAWRKAQKAKKKKKKQTAEEHPEEEEAEEPFPEEEVKKPIPPEPTDPADIEQQVRERVAHSRRRPGEPALIPELSLAGNVTPNDQCPRVEVSRREDVRRRSVYLKVVFNNKEVSRTVSRPLGADFRVHFGQIFNLQIFNWPESLMLQVYETIGHSGATLLAEVFLPIPETTLVTGRAPIEEVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMTSGKVSHSVAWAVGENGIPLIPPLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPNDPNHAPLMQLISVATSGESYVPDFFRLEQLQQEFNFVSEEELNRSKRFRLLQLRNQEVPEFRNYKQIPVYDREIMEKVFQDYEKRLRDRNVIETKDHLDTHRATVAKYLQQVRESVVNRFLTAKHHFLLTDLVVEEEVPNISSEGSGILGLSLFKLAEQKRPLRPRRKGRKKVTAQNLSDGDIKLLVNIIRAYDIPVRKPVVSKFQQPSRSSRTFSEKQTASPSTHSPLHNDDYPLSQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPFRAPNGDYSTASLQSVKDDVYINIFDEVLYDILEDDRERGSGIHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPPVLLGYSKERNIIMERAFDSARSLSEGSYITLFITIEPQLVPGEPIREKMSGMLKKFDTQEDEKLLQATEKFQAECALKFPQRQCLTTVTDMNGKTVFITRYLKPLNPPQELLNVYPNNPQATAELVARYVSLIPFLPDSVSFAGVCDLWSTSDQFLDLLAGDEEEHAVLLCNYFLFLGKKAWLVMGNAIPEGPTAYVLTWEKNYYLIWNPCSGHCYGQFDAFCPLKSVGCLIGPDNIWFNIQHHDSPLRINFDVTKPKLWKSFFSRSLPYPGLSSVQPEELIYQHTDKATAAELQDRIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLERSQGEDIEDDHRAELLKQLGDYRFSGFPLHMPYSEVKPLIEAVYSTGVHNIDLPNVEFALAVYIHPYPKNVLSVWIYVASLVRNR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CFW7-1", "uniprot_id": "C2D2A_MOUSE", "id": "Q8CFW7-1", "name": "Coiled-coil and C2 domain-containing protein 2A", "aln": "MNTNDEKMKIISEDFTGDGVDTEAGRRKKNSKVRRQQRKKKPPASPPEEMVSDKFQDGGQQEVVEEEPETNLLSLTARRGPRSLPPIPSASRTGFAEFSMRERMREKLQAARSKAESALLRDVPTPRPRRLRSPSREKETETEFGTEPSTEVQDTQKEDDTKSYSRIKFRDSVRKIKSKPQLPPGFPSAEEAYNFFTFNFDPEPEESEEKSPVKGGERAHHEDQEGEEG-TQAQERAKKTEEEELLNGKDAEDFLLGLDPTAHDFVAVRAAEYKSARIQLQKEKEILFTPSRLTVPTYKKLPENIQPRFLEDEGLYIGARPEVARTNENIMENRLLIQEPGSKWFGDDGRILALPSPIKPFPSRPSLTTREQSPKAGLETLYKKAEKYVHSRQHMIGSGDPPGNFQLDIDISGLIFTHHPCFSREHVLASKLAQLYDQYLARQQRNKTKFLTDKLQALRKAVQTSLNPEKPHQSLDTTQKTINEYKSEIRQTRKLRDAEQEKDRTLLKTIIKVWKEMKSLREFQRFTNTPLKLVLRKEKVDPKLDEDAYEAEIQAEIHELLEEHMEEYATKMEEYRTSHQQWKAWRKAQRAKKKKKKQTTEEHLEEEEAEESFPEEEVTKPIPPEPTDPAVIEQQVRERAAHSRRRPGEPTLIPELSLAGNVTPNDQCPRVEVSRREDVRRRSVYLKVVFNSKEVSRTVSRPLGADFRVHFGQIFNLQIFNWPESLMLQVYETIGHSGTTLLAEVFLPIPETTLVTGRAPIEEVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMTSGKVSHSVAWAVGENGIPLIPPLSQQNIGFRSALRRADAISSIGTSGLTDMKKLAKWAAESKLDPNDPNHAPLMQLISVATSGESYVPDFFRLEQLQQEFNFVSEEELNRSKRFRLLHLRSQEVPEFRNYKQIPAYDREIMEKVFQDYEKRLRDRNVIETKDHLDMHRATVAKYLQQVREAVVNRFLTAKHHFLLTDLVVEEEVPNISSEGSGILGLSLFKLAEQKRPLRPRRKGRKKVTAQNLSDGDIKLLVNIIRAYDIPVRKPVVSKFQQPSRSSRTFSEKQTASPSTHSPLHNADYPLGQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPFRAPNGDYSTASLQSVKDDVYINIFDEVLYDILEDDRERGSGIHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPPVLLGYSKERNIIMERAFDSARSLSEGSYITLFITIEPQLVPGEPMREKMSDMLKKFDTQEDEKLLQATEKFQAECALKFPQRQCLTTVTDMTGKTVFITRYLKPLNPPQELLHVYPNNPQATAELVARYVSLIPFLPDSVSFAGVCDLWSTSDQFLDLLAGDEEEHAVLLCNYFLFLGKKAWLVMGSAIPEGPTAYVLTWEKNYYLIWNPCSGHCYGQFDAFCPLKSVGCLIGPDNIWFNIQHHDSPLRINFDVTKPKLWKSFFSRSLPYPGLSSVQPEELIYQHTDKAVAAELQDRIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLERSQGEDIEDDHRAELLKQLGDYRFSGFPLHMPYSEVKPLVEAVYSTGVHNIDLPNVEFALAVYIHPYPKNVLSVWIYVASLVRNR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2K1-4", "uniprot_id": "C2D2A_HUMAN", "id": "Q9P2K1-4", "name": "Coiled-coil and C2 domain-containing protein 2A", "aln": "MNPREEKVKIITEEFIENDEDADMGRQNKNSKVRRQPRKKQPPTAVPKEMVSEKSHLGNPQEPVQEEPKTRLLSMTVRRGPRSLPPIPSTSRTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRRLRSP-SKKELETEFGTEPGKEVERTQQEVDSQSYSRVKFHDSARKIKPKPQVPPGFPSAEEAYNFFTFNFDPEPEGSEEKPKARHRAGTNQEEEEGEEEEPPAQGGGKEMDEEELLNGDDAEDFLLGLDHVADDFVAVRPADYESIHDRLQMEREMLFIPSRQTVPTYKKLPENVQPRFLEDEGLYTGVRPEVARTNQNIMENRLLMQDPERRWFGDDGRILALPNPIKPFPSRPPVLTQEQSIKAELETLYKKAVKYVHSSQHVIRSGDPPGNFQLDIDISGLIFTHHPCFSREHVLAAKLAQLYDQYLARHQRNKAKFLTDKLQALRNAVQTGLDPEKPHQSLDTIQKTINEYKSEIRQTRKFRDAEQEKDRTLLKTIIKVWKEMKSLREFQRFTNTPLKLVLRKEKADQKADEEAYEAEIQAEISELLEEHTEEYAQKMEEYRTSLQQWKAWRKVQRAKKKKRKQAAEEHPGDE-IAEPYPEEDLVKPSPPEPTDRAVIEQEVRERAAQSRRRPWEPTLVPELSLAGSVTPNDQCPRAEVSRREDVKKRSVYLKVLFNNKEVSRTVSRPLGADFRVHFGQIFNLQIVNWPESLTLQVYETVGHSSPTLLAEVFLPIPETTVVTGRAPTEEVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMTSGKVSHSVAWAIGENGIPLIPPLSQQNIGFRSALKKADAISSIGTSGLTDMKKLAKWAAESKLDPNDPNNAPLMQLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLHLRSQEVPEFRNYKQVPVYDREIMEKVFQDYEKRLRDRNVIETKEHIDTHRAIVAKYLQQVRESVINRFLIAKQYFLLADMIVEEEVPNIS-----ILGLSLFKLAEQKRPLRPRRKGRKKVTAQNLSDGDIKLLVNIVRAYDIPVRKPAVSKFQQPSRSSRMFSEKHAASPSTYSPTHNADYPLGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPFRAPNGDYSTASLQSVKDVVFINIFDEVLHDVLEDDRERGSGIHTRIERHWLGCVKMPFSTIYFQARIDGTFKIDIPPVLLGYSKERNMILERGFDSVRSLSEGSYITLFITIEPQLVPGESIREK-------FESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVYPNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSDQFLDLLAGDEEEHAVLLCNYFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGRYLIWNPCSGHFYGQFDTFCPLKNVGCLIGPDNIWFNIQRYESPLRINFDVTRPKLWKSFFSRSLPYPGLSSVQPEELIYQRSDKAAAAELQDRIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELLKQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWIYVASLIRNR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0Y9Q9-1", "uniprot_id": "A0A8V0Y9Q9_CHICK", "id": "A0A8V0Y9Q9-1", "name": "", "aln": "-------------------------------------MATAPAAAAPP-------------------------------APRSLPPVPSTSRMGFSELSVRERMREKLKAARSKAEATLSQEDLGPRPRHLKSI-RERKAELRLDKGSGDQLGELQRD-ESLLSSKIKFSDSVKKLKQKSQAQSDYPSAEEAYNFFTLNFDPEPES--IKAGARKRSELNEEEAEEYVETHEEEQEEDETDEDAHLV-KDADLFIMG--QTDEDFLVTKPAECERYSEQLQKEKEFLFIPSMQTVPTSQKMPENMQPRYLEDEGLYAEERPFVSPSNQNILENRILRQEKGKEWFGDDGRILALPNPIKQSSTRPPVFSLEEGIAPELETIYRKAIRTTAANQYLIGPGDFQGPFQLDIDISGLIFTHHPCFSREHVLAAKLAQLYDQYLARKQKNLTELLTDKLRALRNAVQCSMDS--AAASGPTAQQSIPEYKIEIRQTRRLRDAEQEKDRMLLKSIIKVWKQMKSLREFQKFTNTPMKLYLRKEEVDQRSDEKAYEAEIQAEINELQEEYMEEYEKKMEEYKTELQEWKSWKKAQKSKKKKKK----DLREEESVEDYDVGEEPVKPVPPKMVDSLEIEQQVREKANNFRRKPGEPALIPELVLSGSITPSEQCPRAEVLRREDVNKRSAFIKVFFNSKEVSRTVTRPLSSDFRVHFGQIFNLQIFNWPESLKLQIYETTGMSSTTLLAEVFIPVPETTVLTGSAPMEEIEFSSNQRVMLDHEGVGSDVSFSFEADGSNQMTLMTSGKVSNSVSWAVGEKGIPLVPPVSQQNTGIPSALKNIDAIASIGTSGLTDMKKLAKWAAETKLDPNDPNNAALMQMIMVASSGEAHVPDFFRLEQLQQEFNFVSDEEFNRSKRFRLLQLRNEEVAEFRNYKQVPLHEREISEKLFQEYEKRLHERDVIDSKHYLDARRAVVANYLQKVRESVINRFLIAKHHFLLSDLVNEEEIPTLG-----ILGLGLFKLAEPKRPLKPRRKERKKVTAQSLSDGDIKLLVNIIRAYDIPVRKPVTSKLQQPSKSSRSFNEMFAASPSAQSPTNNVDWAFDQVLVRPFVEVSFQRTVCRTTTAEGPNPNWNEELEFPFRAPNGDYSTHSLQSVKDEVFINVFDEVLHDVTEDDRDRGSGIHTRIERRWLGCVKIPFTTIYFQARIDGTFKVNIPPVLLGYSKEKNLGIERGYDSVRNLSEGSYITLFITIEPQLIPGESVREKMNEMLKKFDTQEDEKLLQAAEKYEAECTSKFPSRQCLTTVIDLSGKTVFITRYIKPLNPPQELLDALPNSSQTTAELVARYVALIPFLPDSVSFAGICDLWCTSDQFLDLLAGDEEEHAVLLCNYFLGMGKKAWLIIGNAIPEGQTAYVLTLEQSQYVIWNPSTGCFYRQYDTFCPLQSVYCLISCDNIWFNIQQWDSPVRISFDISKPKLWKPFFSRSLPYPGLCSVQPEELVYQHSDKAAAVELQGRIEKILKEKIMEWRPRHLTRWNRYCTSTLRNFLPLLEQNQGKDVEDDHQAELQKQLGDYRVSGFPIHMPFSEVRPLVEAVHSTGVHTIDVSNVEFALAVYVHPYPQNVLSTWIYVASLVRNR", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *.:: * .******:**:** ** *:*:* ******:*******::* :: ****:*:* ::: * .:.. .. :: *:: :: *::*: **.:*:* *.* ..:***********:******* *. .: :.*: * : .: :*: * .**: *::* . .**:..:.*: : :** *:*:** ** **** :*:***:***:******* ** *: :*:**:***:* *: .************.*** .:**.: : *.. . ***:*:** : . : *::* .*: * *************************:********:***:*:* :::*****:***.**: .::. . * * *::* *** ******::********* ***:******:********:*****:** ****..* : **..********* ** **: *** *****::. *.**:*:*.*::****:* : :* : *: ** **: .* ***:***:. : **:* **:*:*** *:*.:**.:****.** *****.:**.::**.**.*******:***.:**************.****** **:*** * *..*******:*:****::** ** **:******:* ********.*.**********:*********:**:**:**:****:**:**** *: ***:. ***:*******************:********:*.***:* **:***::******************::*:*********:**.:**.*******:* ::*** **:**:*****::*:**::*.::* :** **:***:***:*:**** **::***:*:: ***:*.:. ****.****** ****:**** *******.************:**********..**:****:*** *.* :****: ** :* *:.:.***************:*:*********.******:*********** ******* *:**:*****:*: ****:***********:******:**:*************::***********:*: :**.:**.*.*****************:***.:*** *::*********:**::***: ***.******* *:.*********:**********.. **. *:*********:*******:***.*:****.************************* :******::*.***** ****** *:. *:****.:* * *:*:****:.* ***. ********: :**:**.**:::*****.***********.*******:**::***.*.***.***********:******************:******:.**:*:****:*** *******.****:***:***:**::**:*****.**:.*********:****:****.*******:***", "identical_positions": 1029, "similar_positions": 339, "identity": "62.97%" }, { "cls_id": "homologset.oma.817618", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LK01-1", "uniprot_id": "A0ABK0LK01_RAT", "id": "A0ABK0LK01-1", "name": "", "aln": "MKKLSKRREEIFRKMSEAAT-SSTEEIMDRRLSKGSPAEENRNITETLRGKVREKLKHAKISQGEKSSAELLADTRTCRWS----KTEVLLDEGLSFFILSGEEDSAASRSSRQKTVSESYFKHCASGGGFQIATEGQDEDFMEEVILTDLFEVKAAKYEDDQELIKKQEATIFVPSSSPVASQQKLPKGVLPRILEDEGLYTQKKPETCKKICNKMENRLLSLQEGKCWFEESGEIMSLPSPLRQSWN--FRLCMCKESLNPALKTIHRKAEKYDVGCCFRNRMDGQRETYQLDLNIVGLQFSHHPLFNQEQVLCARLLQLCESFQDRQKQSLSQLLYEKLRALKDATKLASKNPESSQFTKKSLQD------YYQQISDTEQLYDAEREKDHCLLHSVSQTWKQIKS-LRQKQGFTSTPVKLQFHRIKMNTWDEQNQVGMSEGPGDESEETPFPKEDPQETLSHPASDPEGLEAERRKPITLAPQLSFTAELTNIS---KCSLYEQKRRAKMQKLKYFIKIFYNDKQVSCTSVSPLQLDFKVMFQQIFNIQLMYWPETICLEVYEIRKRSTLLVKMYLPLPNKTELKGKTALEYTEFSSDKLVIPMDGGVGSNVPFNLEESENEELCLLTSGKLSYSLSWALDENGMPLTPVSQSLNSAYCSVLRNVDARGVPGLPWIVNSQKLCDWADDIRIDPNNPEYSDITELIMYLRHKGQEIPKYFR--LDQLQDEFNFVSEEEMKRSKRFQLLELRNAG-QLDLFLLQQMPLYDNEIP-DIVFQEFESQAQKDVSISDVNSITAQRINSVNFLRKVRRLIMKKIVKVSKFNLS-----DIVADYEEIVST--SQLTDALCKFIEPRRKLKPQRKERRK-VTAQSISDGDIKILVRILRAYNIPTRKTTSYRTWSMPTYLSSSMSYLRYQNEAKLVPSNEVINEDTVHPFIEVSFQHTVYQTNIANGSHPCWNEEIKVDFISPGHDYSFSSLSKIKDNIHINVFDEVVIEKHEDHCLKSCSAHSYIQKNWLGSISFPFSALLQQPEISGTFQVNIPPILLGYTWSNTYVSPREDCSGQ-NPKECTFLNIFATIEP-QISYVMYNPKVDEFSDQIDILQRAQTFTRNCKAMFPS--RRVMATVFNGEGMQILVTRYIKALNPPQQLLDIFLHDSNATLDLIARFVSLIPFAAETLDENDGADIWMTSECCISLAIGSKEEHAILLCNFFLYFGKKALVILGTSVLEGHVAYVLT--QETGECLLWNPSTGQCYKQFDPFCPLQSVDCLFNDKNVWFNIQQNNTPMAVHFDCSKESFWKQLLPKNFQWTKAQSVQPEEIVYLDTNKSMVEDLKSRIERALKCKMMEWRPKHPTRWNRQCTSVLRQILPKLE----FYTGSFASFE-DSELERLLQFYWVTGFPIQMPYTDVQAVIDAVYQTGVHSSEFPQTEFALAVYIHPYPNNILSVWIYLASLARHQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A140LIW0-1", "uniprot_id": "A0A140LIW0_MOUSE", "id": "A0A140LIW0-1", "name": "", "aln": "MKKISKRREEIFKKMSEAAN-SSTEEMVDRHLSK----EENRNITETLRGKVREKLKNAKISQGEKSSAEPLTDTKTYRWS----KTEVLLDEGLSFFILSGEEDSAVSQSSQQKTVSESYSKQSASGGGFRNTAEGPDEDFMEEVILTDLFEVKAADYEDDQEQIKKQEANIFVPSSSPVASQQKLPKGMLPRILEDEGLYVQKKPETYKKICNKMENRLLSLQEGKCWFEESGEIMSLPSPIRPSWN--YRLCMSKESLNPALKTIHRKAVKSDVGCCFRDRMDGQREMYQLDLNIVGLQFSHHPLFSQEHVLCARLLRLCESLQDRQRQSVSQLLYEKLRALKDATKLISKNPELSQFTTKSLQD------YYRQISDTKQLYEAEREKDHSLLHSVLQTWKQIKS-LRQKQGFTSTPVKVQFHRVKTNTWDEQNQAGVSEGPGDGSGETPLQNEDTEETLSHPASDPEGTEVEKTKPITLVPQLSFTAELTNLS---KCSF---------------------------------------------------------------------------------------------------------------------------------------------------------------VLRNVDARGVPGLPWIVNSQKLCEWADDARIDPHNPDYSDITEHIMCLRHKGQEIPKYFR--LEQLQDEFNFVSEEEMERSKRFQLLQLRNAG-QLDLFLLQPMPLYDNEIP-DIVFQ-------------------------------VRRLIMKRIVKVNKFNLS-----DIVADYEEIVST--SQLTDAICKFIEPRRKLKPQRKERRK-VTAQSISDGDMKILVRILRAYNIPTRKTVSYS---------------------------------------------------------------------SPGHDYSFSSLSKIKDNIHINIFDEVVIEKHE---------------------------------ISGTFQVNIPPILLGYTWSNTYVPPREDCSGQ-NPKECTFLNIFATIEP-QISYVTYNPKVDEFSDQIDILQRAQTFTRNCKAMFPN--RRVVATVFNGEGMHILVTRYIKALNPPQQLLDIFLHDSNATLDLIARFVSLIPFAAETLDENDGSDIWMTSECCISLAIGNKEEHAILLCNFFLYFGKKALVTLGTSVLEGHVAYVLT--QETDECLLWNPSTGQCHKQFDPFCPLQSVDCLFNDKNVWFNIQQNNTPMAVQFDYSKESFWKQLLPKNVQGTKAQSVQ-----------------------------------------------------------------------------------VTGFPIQMPYTDVQAVIDAVYQTGLHASEFPQTEFALAVYIHPYPNNILSVWVYLASLARHQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6DHV5-5", "uniprot_id": "C2D2B_HUMAN", "id": "Q6DHV5-5", "name": "Protein CC2D2B", "aln": "MKKS--QREDIFKKMSEEMDNITAEEIIDKHLQKDLDAEENQNVAKTLRGKVREKLKISKINKGEKSSTEQLIDSEIHQRSKLSPQTEVSLDESLSFFILSGEEGSALGKSSEQRPVNRSYPKCFSLGVNLQNVAESEEEEFMKEFILTDILKVKAADYEDDQEQIKKQKANIFVPSSSPVVNQRKLPKDMMPRILEDEGFYIQRKPEIYKKTCNKMENRLLKLEEGKCWFGESGEIMSLPTPIKQSWN--FRLNVRKEPLNPLLKTIYRKAVKYDLGSSFMNKMEGSREIYQLDLNIVGLQFSHHHLFNQEQVLCARLLQLYECFQDRQQQNVSQLLYEKLKALTDATKLSNENSEINQLTRKSLQD------YYWQISNTKQMYDLERGKDLSLLHSILRTWKQIKS-LRHGQGFTSTPIKLQVQRIKMNKCDEQEQISEMSETEKKNEGKELKNGKKLESLSYLASD--ETEIERIKPITLRPQLSFTAELTSLS---KCSLHEQKRRAKIQKLKYFIKIFYNNKQVSCTSVSPLQFDFKVMFQQIFNIQLMYWPEVICLEVYEKSKRTSLLAKLYIPLPNYTELKGKTALQYVEFSSDKLVMPADGEVGSNVPFLLEGNGTEELCLLTSGKLSYSLSWSLDENGLPLIPMPQSLRSSYCSMLRNVDARSVPGIPWLMNEQKLFEWANEVRIDPNNPEYSDLMESVTYMRLKGQDIPKYFR--LEQLQDEFNFVSEEEMAKSKRFQLLQLRNAG-QLDNFLLQQMPLHDTEIP-DLVFQEYESQKEKEVSVSDVNSITAQRINSANFLKKVRRLIMKRIVKISKCNLS-----DIVNDYEEIVST--SQLTDAVCKFVEPRRKLKPQRKERKK-VTAQAISDGDIKILVRIVRAYNIPTRKTTINGSLDMPTCLKSSISCLRHRETIKSVASDETLHEDTVHPFVEVSFQHTVYKTNTASGSHPCWNEEIKVDFVSPGHDYSFSSLSKIKDNIYINIFDEMMTEKHEDHCLKSCSGHSYIRKNWLGCIVFPFSALLQQSEISGTFQVTIPPVLLGYTWSNTYVFPKEDSNEQ-NLKECTFLNIFATIEP-QISYVTCNPTLDKFLDQTEVLQRAQIFKKNCKAMFPN--RRIVTTVFNDEGIQFLVTRYIKALNPPQQLLDIFLHNSNATFDLIARFVSLIPFVPNTPDENDGSDIWMTSEHCISLAIGNKEEHAILLCNFFLYFGKKALVLLGTSVLEGHVAYVVT--QETNEYLLWNPSTGQCYKQFDPFCPLKSVDCLFDDRNVWFNIQQNNTPMAVFFDYSKESFWKQLLPKNVQGTKIQSIQPEEIIYFETDKSMVEDLRNRIERTLKSKVMEWRPKHPTHWNRQCTFILRQILPKLE----FGIGSFVSSEGDNEFERILQFYWVTGFPIQMPYIDVQSIIDAVYQTGIHSAEFPQTEFALAVYIHPYPNNILSVWVYLASLVQHQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1ZAV1-1", "uniprot_id": "C2D2A_DROME", "id": "A1ZAV1-1", "name": "Coiled-coil and C2 domain-containing protein 2A", "aln": "MEAALSRKTAKKKRKTHTTRGYRKREQEVQKLIR----ATEGRISGPEHDMEALSLQFFHGFEGEMQQENDFAVEDCQESD----------ED------SGGELAEEPTDSPSQTFIHIDLHDPPLAWGQLFKQRHYYDESLLYRPSNTLHFQLHLSDLSELKDSQIRMLNRYQEQSKS---KSGKLGSDLIGQLSGQKPASFLMGKHLYRSVCHRRFQSVFFPPMPPSELKGLPSRRCLKLCLKQLRFSLHPQLLEEHRLAQQLEDLFDVYSQQRKQRICRKLREELEIARQVALKLLASAGQDQTAEVKRQLKLTRQLRQRYYAESAAQRNLLQRLLKEWAKLKELRRQQRFQCTRFQLGLRVVHPPDLEASYCAWKESFETDLAEVYREHLELFYTRLRLWTDQKSHSRTATGHSKPPRKPQFDRIMASLRKEYDKT-FKDPEEPYVEVFRLHADEATARLSIPGGDQLPKARNYFLKIFLDGQFVGQSRTYRLEPDLQISINECIGVLLERSLPENLNIWLYEKSTLTPK------------------------------------------------------------------------------------------SRRLAQISTPLVLSSKDDAVQEKLSFQALSSTQLAGDVYLYYEYRSTEGWGSALHLDDVQRLPDALRQTLLPQSLPALPQASKELVTPRPPSGRIKKSQLPSLIFAEQQLQFCGLDVLLDNRRFQLLHSRHQQRNLHTKQLRFVPALEQEISEEEPLPDGRGTVQLLEPGTYWNPIDLHKHRGRKFLQLLYEVIASQSARRAKALQTPLPLLLLAEDSDRSSGTGWTALWRAFCSVFQGQRNSLPREPSGWSGHQSAPDLFKSFCVSLHVVRATGVPVRSRHILNLNERRSSAGGDMS--------TSLFVTQTLMYSNVRPFVTLSYGQRLCRSRTAEGSNPTWN--------EQLQLQIQSQFGDLRDDLKISLFDELIEQQYSDEAS---DVYQRVQCNWLGEFRVPINSLLASRTFEGCIELAMPKVLVGYKRPLIDSVTNMPTDQYPEFKEAVHLWFYLSIEPGGGDLAPLHSCALACAEKPELQQYLDERRLELQQLLPQPQRYVEPLVCTAQGKRVCLTRLMDPVPLPP----AAVPSGENPLEICIRYVSLLSHLRSYDPCQGFRGVWLDNQSLLDSTWCSVKDLGVLLCNYMLSLGLECWLILGVSCPHGECSFVLFRQPETAELFLVSPATGKRYQLQDVHCPLRRIYCVVGKQNIYFNIQTETRVSMTHFNLQDGACWFPLFRRRVPAPQSGVQKLD---YAYKRSYELSQLQKHIERKIMKKISAWRTTRKTIWNRAFQPRLHKILCDMEDLSTFSRGRYDEPIFSEQLEREFPNYRLYGFTLNFAYTNLAAISERIRTSCIHYNHDASVEFCVAVHLHAHANDVLSVWLFLLSMVPLVE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :: :: :. .* ::* : : .:: . :. .*: : :** .. : : . . :: .** . *. * : . . : . :*.:: . * :::: :. .: :: : *.* .. ** ..:: :: :: . :. *:: : :: . : . .* :: . : :. * *: :. : . : . *: *:::. ..: :.:: :* *: :. ::.: * * :: *.: : : *: : :: * .. : :. *::: : *.: ** * *.:..* * *..*: . .* :: . : . ** ..* : * * *: :. :. : *: . .:.. . : : *:* : : : * .: : : * . * * * :::::* . : : .:*****. *: :*. *: :* : **. : : : .:* .: .: * : :. * :. .* : * *.*...: :*: *:. . . : . .: : ::::** .:*.*. . : *.:..::*:: *.:***:: :::. :.* ::: :* :*:**. . .. . : **...* :: :*** . . :. :: :: * : : : ::*. * : . * . :* :. :** :..: * : ..: .::: *:***:.. . :. .:*: .: :. : . :: .:****::* :* :. : **.* .*. ::*: ** * :* .*:**: :: * .***: : *:...:*::**** :. . *: .. : * *: :.. .: : : **.:::.* :: :: : : : :* . ...**.:**::*.:.*::****::* *:. ", "identical_positions": 156, "similar_positions": 394, "identity": "10.57%" }, { "cls_id": "homologset.oma.817628", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DC63-1", "uniprot_id": "FBX3_MOUSE", "id": "Q9DC63-1", "name": "F-box only protein 3", "aln": "MAAVEAETGLLTLESLPTDPLLLILSFVDYRDLINCCYVSRRLSQLSTHDPLWRRHCKKYWLISE--EEKAGKSQCWRSLFIETYSDVGRY-IDHYAAIKKAWRDLKKYLEPRCPRMVLSLKEGAREEDLDAVEAQIGCKLPDDYRCSYRIHNGQKLVVP-------GLLGSMALSNHYRSEDLLDVDTAAGG----FQQRQGLKYCLPLTFCIHTGLS--QYIAVEAAE-----GRNKNEVFYQCPDQMARNPAAIDMFIIGATFTDWFTSYVNNVVSGGFPIIRD------QIFRYIHDPECVATTGDITVSVSTSFLPELSSVH--PPHYFFTYRIRIEMSRD-----ALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGR-IYEYTSCTTFSTTSGYMEGYYTFHFLYFKD---KVFNVAIPRFHMACPTFRVSIARLEMGPDEYEEMEEEAEEEEEEE-NDDSADMDESDESDADENESDEGEGEARRRRVFDVPIRRRRCSRLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ABP9-1", "uniprot_id": "FBX3_RAT", "id": "D4ABP9-1", "name": "F-box only protein 3", "aln": "MAAVEAETGLLTLESLPTDPLLLILSFVDYRDLINCCYVSRRLSQLSTHDPLWRRHCKKYWLITE--EEKARKNQCWKSLFIATYSDVGRY-INHYAAIKKAWDDLKKYLEPRCPRMVLSLKEGAREEDLDAVEAQIGCKLPDDYRCSYRIHNGQKLVVP-------GLLGSMALSNHYRSEDLLDVDTAAGG----FQQRQGLKYCLPLTFCIHTGLS--QYIAVEAAE-----GRNKNEVFYQCPDQMARNPAAIDMFIIGATFTDWFTSYVNNVVSGGFPIIRD------QIFRYIHDPECVATTGDITVSVSTSFLPELSSVH--PPHYFFTYRIRIEMSRD-----ALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGR-IYEYTSCTTFSTTSGYMEGYYTFHFLYFKD---KVFNVAIPRFHMACPTFRVSIARLEMGPDEYEEMEEEAEEEEEEE-NDDSADMDESDESDEDENESDEGEGEERRRRVFDVPIRRRRCSRLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UK99-1", "uniprot_id": "FBX3_HUMAN", "id": "Q9UK99-1", "name": "F-box only protein 3", "aln": "MAAMETETAPLTLESLPTDPLLLILSFLDYRDLINCCYVSRRLSQLSSHDPLWRRHCKKYWLISE--EEKTQKNQCWKSLFIDTYSDVGRY-IDHYAAIKKAWDDLKKYLEPRCPRMVLSLKEGAREEDLDAVEAQIGCKLPDDYRCSYRIHNGQKLVVP-------GLLGSMALSNHYRSEDLLDVDTAAGG----FQQRQGLKYCLPLTFCIHTGLS--QYIAVEAAE-----GRNKNEVFYQCPDQMARNPAAIDMFIIGATFTDWFTSYVKNVVSGGFPIIRD------QIFRYVHDPECVATTGDITVSVSTSFLPELSSVH--PPHYFFTYRIRIEMSKD-----ALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGR-VYEYTSCTTFSTTSGYMEGYYTFHFLYFKD---KIFNVAIPRFHMACPTFRVSIARLEMGPDEYEEMEEEEEEEEEEDEDDDSADMDESDEDDEEE----------RRRRVFDVPIRRRRCSRLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6H7H7-1", "uniprot_id": "FBX3_BOVIN", "id": "A6H7H7-1", "name": "F-box only protein 3", "aln": "MAAMDTESAPLTLESLPTDPLLLILSFLDYRDLINCCYVSRRLSQLSSHDPLWRRHCKKYWLISE--EEKTQKNQCWKSLFIDTYSDVGRY-IDHYAAIKKAWDDLKKYLEPRCPRMVLSLKEGAREEDLDAVEAQIGCKLPDDYRCSYRIHNGQKLVVP-------GLLGSMALSNHYRSEDLLDVDTAAGG----FQQRQGLKSCLPLTFCIHTGLS--QYIAVEAAE-----GRNKNEVFYQCPDQMARNPAAIDMFIIGATFTDWFTSYVNSVVSGGFPIIRD------QIFRYVHDPECVATTGDITVSVSTSFLPELSSVH--PPHYFFTYRIRIEMSKD-----ALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGR-VYEYTSCTTFSTTSGYMEGYYTFHFLYFKD---KIFNVAIPRFHMACPTFRVSIARLEMGPDEYEEMEEEEEEEEEED-DDDSADMDESD-DDEEE----------RQRRVFDVPIRRRRCSRLF", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1R287-1", "uniprot_id": "F1R287_DANRE", "id": "F1R287-1", "name": "", "aln": "----MATSIALSLDNLPSDPLLLVLSFLDFRDLISCSFVSRRLNELTGHNPLWKRLCQKHWLLSE--ADKTQRGLSWKDLFREYYADLGRY-FDYYSTLKKAWDDLKNFLNQKCPRMIASLKEGVREDELDTIEAQIGCKLPNDYRCSYRIHNGQKLVVP-------GLMGSMALSNHYRSEDLLDIETAAGG----FQQRKGMRQCLPLTFCFHTGLS--QYMALETTE-----GRTRSEIFYQCPDQLAQDPSAIDMFITGSNFTEWFTSYVDNVVTGEYPIIRD------QIFRYVHDKRCVATTGDITVSVSTSFLPELSSVH--PPHFFFTYRIRIEMAKS-----ALPEKACQLDSRYWKITNANGNVEEVRGPGVVGEFPVMTPGK-VHEYASCTTFSTTSEYMEGHYTFHRLKNKE---EVFDVSIPRFHMVCPPFRESVVRSSSVSEVSAPYDDE----------------NSSDTDDYEE----------GEMRGMNMADPGGRCPRHV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9LND7-1", "uniprot_id": "SKI16_ARATH", "id": "Q9LND7-1", "name": "F-box protein SKIP16", "aln": "----------MGLEDAGDLVLHIVLSKIGPENTARVACVSKRLKVSASEESLWSIFCSNDLNISTPLDPHGDPAPSFKRAYQLWRESFRMYPWNLVKRVRLCWDNLKQWLTLNFPEAKATLRKGVTEDDLQEFETSLKVKLPLPTRLLYRFVDGQELSSPNGLDGSLGLIGGYSAYSHDVNVYLLPLKEVMRETKESFMRDLGFSSRLDLIVMAASVVASLKIFLLDCTTGQLFTGTSNRQLLPCVPDALVRSVHDTNGDQQQDAMLLWLEEHGRRLQTGTINVRQQNNVKSISLFPEIPPLCSVSVTNGVQVRASSVFIPEISNLRDQPPAYWYAYSIRMSLMPEGCILNGTHHSSCQLYWRHWVIRADNEVIDNVNGEAVIGKYPLLQAGEEEFVYESCSSFPTTAGSIDGSFTFVPGSLRDPKGSQFEVKVVEFPLELPDYIF-------------------------------------------------------------------------", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:. * ::** :. .: . **:**. : .:.** *.: :: : .:: : .. * : :: .* :**::* . *. :*::*. *::*: .*:.: *** * **: :**:* * **:*. : .* . ** :. . * : *: * * . : :: : : :: : * .. ::: ** :.:. : : *: .: : :* : :: .:* : .*:.*..: * .*: *:**:*.:: ** ::::* **:.: . . ..:*** *:* * : :::*.* .*:*::*:: .*. . * **::*.**: ::* :** :: . *:* : .* : * : ", "identical_positions": 86, "similar_positions": 146, "identity": "16.57%" }, { "cls_id": "homologset.oma.817637", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q68FQ8-1", "uniprot_id": "DLEC1_RAT", "id": "Q68FQ8-1", "name": "Deleted in lung and esophageal cancer protein 1 homolog", "aln": "MEPESKKELQSPASSFVMSS-ETMWESTPRQPESTSLSWSPRKS-LRSLTVFTDYCQFGYPTRSLRAGFQELPPLPEPQTLRLRPASLRTQDISHLLARVFRNLYTAQVIGDDLSDSLIKARGSEDARHEEFLDQLQQARAIYKKRLDDVAMLEKHITQARARDIAETEHATK--QGRLHVVEAPVKLPPVKTVFRWCIDNELMQKHHLISTEDYYNDPLPFCPAPKRSPTPMYSKMTFSCEKRFTHKSDLERKAEEHCR-KLVEFD-DLEYTTDSLRS--VSKTKGKTKVTIKKASTPANKKWMEHLQVPQRALDRRLLARMQNRNHYLKNPRFFPPNTPHGGKSLIVPSRKPERRGSLS----AKPEWRCVCSSRRIPG-NVSFRVNLDL--VYGGPQTLASQGSVPEESGVLGSTS-----GMAFDP----------------------------------QGPR--VRLFSAVRSRGVDPWEPVWASSGHPKWGGAGAGAYSHVTLAWYVDYLFLLL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLA1-1", "uniprot_id": "DLEC1_MOUSE", "id": "Q8BLA1-1", "name": "Deleted in lung and esophageal cancer protein 1 homolog", "aln": "MDSESKEEQQCTASSAVMSSLETQFLSVPHQLESASLSWSIRKS-LHSSTVLMDDCHFGFPTRSLRAGFHALPPLPEPQTLRLRPASLRTQEISHLLARVFRNLYTAQVIGDDLSDSLIKARGSEDARHEEFLDQLQQARAIYKQRLDEAAMLERHIMQARARDIAETEHTTK--QSRLQVVETPVKLPPVKTAFRWCLDSKLMRKHHLISTEDYYTDPVPFCPAPKDKSTLGCSKLTFSCEQRFLRKSELDREAEEHCR-QLTECD-DFEYTVDSLGS--ISKAKERTTDSVKKTSRPKNKKWMEHLQVPQRALDRRLLASMENRNHFLKNPRFFPPNTPHGGKSLIVPLSKPERRASLN----AEPEWSCTDAPVFLAKPSVGFFTDYEIGPVYEMVIALQNTTSTSRFLRVLPPSSPYFALGLGMFPGKGGIVAPGMTCQYIVQFIPDCLGDFDDFILVETQSPHTLVIPLQARRPPPVLTLSPVLD-CGHCLIGGVKITKFICKNVGFSVGKFCIMPQKSWPPPSFRAVATTGFVEQPPFGVMPSVFELAPGYAILLEVLFLPTGLGQAEETFIIVCDNCQIKEVVVVGTGQLVALDLIHISGGKNEPDPGELKDLTAQYFIRFEPENVQSTPKKQLIIRNAT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y238-1", "uniprot_id": "DLEC1_HUMAN", "id": "Q9Y238-1", "name": "Deleted in lung and esophageal cancer protein 1", "aln": "METRSSKTRRSLASRTNECQ-GTMWAPTSPPAGSSSPSQPTWKSSLYSSLAYSEAFHYSFAARPRRLTQLALAQRPEPQLLRLRPSSLRTQDISHLLTGVFRNLYSAEVIGDEVSASLIKARGSENERHEEFVDQLQQIRELYKQRLDEFEMLERHITQAQARAIAENERVMS--QAGVQDLESLVRLPPVKSVSRWCIDSELLRKHHLISPEDYYTDTVPFHSAPKGISLPGCSKLTFSCEKRSVQKKELNKKLEDSCRKKLAEFEDELDHTVDSLTWNLTPKAKERTREPLKKASQPRNKNWMNHLRVPQRELDRLLLARMESRNHFLKNPRFFPPNTRYGGKSLVFPPKKPAPIGEFQS---TEPEQSCADTPVFLAKPPIGFFTDYEIGPVYEMVIALQNTTTTSRYLRVLPPSTPYFALGLGMFPGKGGMVAPGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTLSPVLD-CGYCLIGGVKMTRFICKNVGFSVGRFCIMPKTSWPPLSFKAIATVGFVEQPPFGILPSVFELAPGHAILVEVLFSPKSLGKAEQTFIIMCDNCQIKELVTIGIGQLIALDLIYISGEKSQPDPGELTDLTAQHFIRFEPENLRSTARKQLIIRNATHVELAFYWQIMKPNLQPLMPGETFSMDSIKCYPDKETAFSIMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVLEEVPEP--VSSEAESLGHSSYSVDDVIVLEIEVKGSVEPFQVLLEPYALIIPGENYIGINVKKAFKMWNNSKSPIRYLWGKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIEDSPSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDVSPFDIEPSSGQLHSLGECRVDITLEALHCQHLETVLELEVENGAWSYLPVYAEVQKPHVYLQSSQVEVRNLYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEFCMVTVSPKHGLLGPSEECQLKLELTAHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITISKESSDCSTEQWP---GHPKELRLDFGSAVPLRTRVTRQLILTNRSPIRTRFSLKFEYFGSPQNSLSKKTSLPNMPPALLKTVRMQEHLAKREQLDFMESMLSHGKGAAFFPHFSQGMLGPYQQLCIDITGCANMWGEYWDNLICTVGDLLPEVIPVHMAAVGCPISSLRTTSYTIDQAQKEPAMRFGTQVSGGDTVTRTLRLNNSSPCDIRLDWETYVPEDKEDRLVELLVFYGPPFPLRDQAGNELVCP----------------DTPEGGCLLWSPGPSSSSEFSHETDSSVEGSSSASNRVAQKLISVILQAHEGVPSGHLYCISPKQVVVPAGGSSTIYISFTPMVLSPEILHKVECTGYALGFMSLDSKVEREIPGKRHRLQDFAVGPLKLDLHSYVRPAQLSVELDYGGSMEFQCQASDLIPEQPCSGVLSELVTTHHLKLTNTTEIPHYFRLMVSRPFSVSQDGASQDHRAPGPGQKQECEEETASADKQLVLQAQEN---MLVNVSFSLSLELLSYQKLPADQTLPGVDIQQSASGEREMVFTQNLLLEYTNQTTQVVPLRAVVAVPELQLSTSWVDFGTCFVSQQRVREVYLMNLSGCRSYWTMLMGQQEPAKAAVAFRVSPNSGLLEARSANAPPTSIALQVFFTARSSELYESTMVVEGVLGEKSCTLRLRGQGSYDERYMLPHQP-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UUL3-1", "uniprot_id": "A0A8N7UUL3_DANRE", "id": "A0A8N7UUL3-1", "name": "", "aln": "-------------------------------------------------------------MADETEPKALTLKSSEPSINRHTPASKTTQDISHLLASIFNDLYSTEVIGKDTVSNLSKSRRRGNSYHEKYVEELQQVHSEYNRRIQNADMLETHIIQARLQAAAKEEHDRNKILEEVGEAYQQLGLPPVKSAFKWCVDSGLLRSNSLICPLDYTTVHNPVVKSPKARSSPGFAKPTFSYNMHISTELQDDGYTPLPPHAHSAHSLLEYSEETITLSS---SPES--SSINDTELGLVAKASWMEKTSAKSHAEDRASLKKHKDRHKFLHNPRFLLPNTQHGGKSLIIPGKKKLENVGKSRKNNGRERSLEGHAPIFTANPPVIFFSDYRVGQVYETSVELKNMTASSRHIRMIPPTSPHFSVGLGRFPGEGGIVAPGMSCQYMVRFAPDSLADYEDALVVETQMLYPLIIPIEACRSPPILTLPAVMD-CGFCLVGGVKFMEVLCRNEGLSAGTFCVMPKKQWPASSLRSAVKSTFTEQPPFAISPSIFGLHPGQATVIEVVFFPTTPELSTQDFTIVCDNCQVKDITLQGTGQLITVELLSVSGGEDQPEFAELCDITADHYVRFNTTNPHSTLQKTLVVKNNTHLELPYHWQIMKPSLQCLLPGETPDPSSIQHLLDTDSAFSISPVIGILNPAQEHEFLLTYAPKDIKDYHSVCHLVIMDVPSPPKVCDDGTCPDT-ALHANNVTILEVEVKGSTEPYKILLEPYAVLIPGETYIHNTICKRFKMWNHSKSVIHFEWERVIDSHVIEVEPSSGVIEMNECFDMELYLTGRSPGHFTSTLQCHILHHPKTIGLAIEATFKGPHCSLNVPSLDFGLLQMGNERILTIEVTNNSLLDAHWSLEVLSQTQKLIDGQVH---INPNKGVLAALESCSVDVAFRAMHCQVFESVLQLSVLNGTGCHVSIHAVVQSPQVCLLNCELLFADLYVGVSQTGSVTLFNQTLLPAHFTWGRLQGSQAHLCSAVFSPSAGSLGPNAKTEVSVSFTAHTVEDLTEVNGVCEVKGMENPLVLGIFSKAKPLRVSYSLLCNGINSGD-----GDHQPILLDFTEHEPAVIGKSVKRQLLITNNTAITAPFTVDTEYFTGDCPS--QSEGNSERSSAPFHSI-QAKKIQQKAYDEFVSRLLSHGRGATFYVEPKSGMLGPFESQTINITTFTNMWGDYQDNLICKVGDLNPTHIHMKMSVRGCPVYFQMIGPQ-PDNQNQGPVIRFGSHVSGGDTVSRSLRLINTSPYDIRMDWVTYNLEAGDGKLIDLLLACGEPFPLKDADGNEVVGGLDSSVMFPSTWDDSHTPSREGTSSTFMTQSDDFVENGEECDGEDGSGASESLAPVKKLFSVFLKPHEGTLSDYPYCITPQQTVVPAGGSSTIHLSFTPLILS-CSTNQR-CLGYALGFMSLDSKLALVTPGKVERVRGYELQPLRLDMQANVKPAILSVQMAEDTEVLEFSAAASDTLDG--ASQTQESRITRTFRLKNDTDMALSFKLSTNPPFSVLLPRQSLKLISSSPAYRHTQGLSGPGDEMRLFLLQPKNIIQVKVAFHNSASLLACVNGACEESDSQLSASLLCSDDGGKTLQFQENLTIQYSNNSIQTVSLYARLALPTLHLSSATVDFGTCYVGQTTVKEIYLHNRGGSCSYWTTLTDGNE------VFRVSPDSGLLKPLGD-PASCRQLLQISFTPREQKEFQTIFTVQGLLGETPLVLKVSGRGSFDESFVSPITDSSQNNTE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8V1ADC0-1", "uniprot_id": "A0A8V1ADC0_CHICK", "id": "A0A8V1ADC0-1", "name": "", "aln": "-------------------------------------------------------------------------------MAQRSPSSRS-QDISHLLSSTFKDLYTGDVIGADIEANWLKSRGGDDAYHEAFTEELQKLVVEYNHRLTEADAVEENIIQAQVRAKAEEERALNVLKGDAGKDFHKMGLPPVASSFRWIVDNELLRKNHLTCPDDYITDKLPVTRAPKGKAEPGYVKETFSFKQRVSSDSRDQ--MSAHLQKISAH-LPSVSLSTLILPS---TPDSYHRTKRTSKKSSASQKADWKGSKCKAEREECAYLAKLEKRQNFLKNPRFFPPNAPHGGKSLVMS-QGQVEQIISNTSAECNTGDIS-FVPVFLAKPPTVFFSDYEVGRVYEITVELQNITSTCHRVGVIPPSTSVFSIGPGKFPGKGGMIAPGMTCQYTVQFVPESLADYTDYIWVQTPVSEPLLIPIQAKRAPPVLTLPRIID-CGFCLVGGIKVTVILCRNVGFSTGKFCIMPQEAWPPPNFRAVATLGSVIQDPFGIYPAVFELAPGQSTRVKVVFFPSLPEVSQQTYTIVCDNCQVNDVTVTGVGQLIALELLHVTGGESSSEPDEVTDVTAQHLIRFDPQNPHTTTQKILVIRNATHVELPFYWQIIKPNLQPIVPGETAHFVTPEYNRETESVFSLSPKQGVLLPHADHDFTLTYTPQELKIYHSVIQLVLRDIPESPSLVKGRILQNIPEYTAEDVIALDIEVKGSTEPFQLLLEPYAVIIPGENFLGVKVRRTFKMWNNSKSPIKYTWENITDCTIMEVEPLTGVIDRNEHCEFELMITGIRPGCVSHNLQCQIKHSAEPVVLHVEAAFKGPLLHISIPSLRLGLIKPGETVVGTFEIQNLCQLPARWRMQESQACLAERNEEVSPFTIQPPAEEIPPLGSCSVSVQYMSLLCQRLHTVLELEVENGERSYLPVSVEVQTPQACLISSHLVLTEMYTGVPVKATSKLFNQTRLPAKYSWGNLIGSQAAFCSATVTPASGILAPNEEKEFCIELTANITGELKGVALSCSIEDMIEPLFLSISGEVKGLHVTYSVPCEGGDASDERKMLQSPRDLLLDFGS--EVALKDIVKRQLILTNHTAISAPFKLEAVYFTGSSPTPEQSVSLSSDYLVKRRGP-ITKHAAKRAQSEFAAAMLSHGKGVAFHVQPSSGTLQAFQQLIIEITAYNNMWGEYSDDLVCKVGDLQPTLIPMQMTVKGCPIFLQMTGP-----QTQRPIIRFGTHVSGGCPVFRNVQLNNPTAFDIRLDWETYNQEEGDKKLVDLLMLFEDPFPPKDMAKNETASTGSNSEIVLG-LDQPPVPCG-SIHPSLQTTDE---SSNTECEEE---GIITQEPTRQKIVSVLLRPHEGVPADSPYSITPRQIVVPGGGSSSVCISFTPHVLP-EPVAEVRCDGFVLGFMSLDDELAKTVPDKVHRRDGYDTAPLRIDMRASVRQALLKVDTDHDGGMVFYSVASDLLPDQPLLGVLSDSVLTQSLKLTNCTKVPLYFSLLLSAPFS--LTSTDLKKSTNTFHSETEETEQEP-----QLVLYPQQNMLVKVSFHITLKLLMYQH--LPDTQMLPGFQVLQGESGERKLKFSQNLIIEYSNHSTQLVPVTAYLTVPVLELSCNMVDFKTCLVAQTKTEHVFLCNRSSCRIYWTALLDQQERHSDLEVFSVSPANGILEAREG-EQPTKDMLQITFTARSDTEYETILTVTGMLGEKPCKLQIRGQGTYDEKYEDMY---------", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:* *:*****: *.:**: :*** : . *:* : ** : ::**: *::*: : :* :* **: : *: *: . : **** : :* :*. *::.: * .. ** . *. :** . * *** : : . : : .. . . . * . . .: . : : . : * :.*:::*:****: **: :*****:.. . . . . * : : ** * . : . :: .:: * . * : :.* *. : . : .*. ** . . .. : :: ", "identical_positions": 71, "similar_positions": 104, "identity": "3.96%" }, { "cls_id": "homologset.oma.817656", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5EA01-1", "uniprot_id": "B4GA1_BOVIN", "id": "Q5EA01-1", "name": "Beta-1,4-glucuronyltransferase 1", "aln": "MQMSYAIRCAFYQLLLAALMLVAMLQLLYLSLLSGLHGQEEQDQYFEFFPPSPRS----VDQVKAQLRTALASGGVLDASGDYRVYRGLLKTTMDPND----------VILATHASVDNLLHLSGLLERWEGPLSVSVFAATKEEAQLATVLTYALSSHCPDMRARVAMHLVCPSRYEAAVPDPREPGEFALLRS-CQEVFDKLARVAQPGVNYALGTNVSYPNNLLRNLAR--EGANYALVIDVDMVPSEGLWRSLREMLDQSKQWAGTALVVPAFEIRRARRMPMNKNELLQLYQVGEVRPFYYGLCTPCQAPTNYSRWVNLPEET--LLRPAYVVPWQDPWEPFYVAGGKVPTFDERFRQYGFNRISQACELHVAGFDFEVLNEGFLVHKGFKEVLKFHPQKEAENQHNKILYRQFKQELKAKYPDSPRHC", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1RUS9-1", "uniprot_id": "F1RUS9_PIG", "id": "F1RUS9-1", "name": "Beta-1,4-glucuronyltransferase 1", "aln": "MQMSYAIRCAFYQLLLAALMLVAMLQLLYLSLLSGLHGQEEQDQYFEFFPPSPRS----VDQVKAQLRTALASGGVLDASGDYRVYRGLLKTTMDPND----------VILATHASVDNLLHLSGLLERWEGPLSVSVFAATKEEAQLATVLTYALSSHCPDMRARVAMHLVCPSRYEAAVPDPREPGEFALLRS-CQEVFDKLARVAQPGINYALGTNVSYPNNLLRNLAR--EGANYALVIDVDMVPSEGLWRGLREMLDQSKQWAGTALVVPAFEIRRARRMPTNKNELLQLYQVGEVRPFYYGLCTPCQAPTNYSRWVNLPEET--LLRPSYVVPWQDPWEPFYVAGGKVPTFDERFRQYGFNRISQACELHVAGFDFEVLNEGFLVHKGFKEALKFHPQKEAENQHNKILYRQFKQELKAKYPDSPRHC", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "O43505-1", "uniprot_id": "B4GA1_HUMAN", "id": "O43505-1", "name": "Beta-1,4-glucuronyltransferase 1", "aln": "MQMSYAIRCAFYQLLLAALMLVAMLQLLYLSLLSGLHGQEEQDQYFEFFPPSPRS----VDQVKAQLRTALASGGVLDASGDYRVYRGLLKTTMDPND----------VILATHASVDNLLHLSGLLERWEGPLSVSVFAATKEEAQLATVLAYALSSHCPDMRARVAMHLVCPSRYEAAVPDPREPGEFALLRS-CQEVFDKLARVAQPGINYALGTNVSYPNNLLRNLAR--EGANYALVIDVDMVPSEGLWRGLREMLDQSNQWGGTALVVPAFEIRRARRMPMNKNELVQLYQVGEVRPFYYGLCTPCQAPTNYSRWVNLPEES--LLRPAYVVPWQDPWEPFYVAGGKVPTFDERFRQYGFNRISQACELHVAGFDFEVLNEGFLVHKGFKEALKFHPQKEAENQHNKILYRQFKQELKAKYPNSPRRC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZHA1-1", "uniprot_id": "D3ZHA1_RAT", "id": "D3ZHA1-1", "name": "Beta-1,4-glucuronyltransferase 1", "aln": "MQMSYAIRCAFYQLLLAALMLVAMLQLLYLSLLSGLHGQEEQEQYFEFFPPSPRS----VDQVKSQLRTALASGGVLDASGDYRVYRGLLKTTMDPND----------VILATHASVDNLLHLSGLLERWEGPLSVSVFAATREEAQLATVLAYALSSHCPEMRARVAMHLVCPSRYEAAVPDPREPGEFALLRS-CQEVFDKLARVAQPGINYALGTNISYPNNLLRNLAR--EEANYALVIDVDMVPSEGLWRSLREMLDQSNHWDGTALVVPAFEIRRARRMPMNKNELVQLYQVGEVRPFYYGLCTPCHAPTNYSRWVNLPEES--LLRPAYVVPWRDPWEPFYVAGGKVPTFDERFRQYGFNRISQACELHMAGFNFEVLNEGFLVHKGFKEALKFHPQKEAENQRNKILYRQFKQELKARYPNSPHRC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BWP8-1", "uniprot_id": "B4GA1_MOUSE", "id": "Q8BWP8-1", "name": "Beta-1,4-glucuronyltransferase 1", "aln": "MQMSYAIRCAFYQLLLAALMLVAMLQLLYLSLLSGLHGQEEQEQYFEFFPPSPRS----VDQVKSQLRTALASGGVLDASGDYRVYRGLLKTTMDPND----------VILATHASVDNLLHLSGLLERWEGPLSVSVFAATKEEAQLATVLAYALSSHCPEMRARVAMHLVCPSRYEAAVPDPREPGEFALLRS-CQEVFDKLARVAQPGINYALGTNTSYPNNLLRNLAR--EEANYALVIDVDMVPSEGLWRGLREMLDQSNHWDGTALVVPAFEIRRSRRMPMNKNELVQLYQVGEVRPFYYGLCTPCHAPTNYSRWVNLPEES--LLRPAYVVPWRDPWEPFYVAGGKVPTFDERFRQYGFNRISQACELHVAGFNFEVLNEGFLVHKGFKEALKFHPQKEAENQRNKILYRQFKQELKARYPNSPHRC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3I2H6-1", "uniprot_id": "G3I2H6_CRIGR", "id": "G3I2H6-1", "name": "Beta-1,4-glucuronyltransferase 1", "aln": "MQMSYAIRCAFYQLLLAALMLVAMLQLLYLSLLSGLHGQEEQEQYFEFFPPSPRS----VDQVKSQLRTALASGGVLDASGDYRVYRGLLKTTMDPND----------VILATHASVDNLLHLSGLLERWEGPLSVSVFAATKEEAQMATVLAYALSSHCPEMRARVAMHLVCPSRYEAAVPDPREPGEFALLRS-CQEVFDKLARVAQPGTNYALGTNISYPNNLLRNLAR--EEANYALVIDVDMVPSEGLWRRLREMLDQSNHWDGMALVVPAFEIRRARRMPMNKNELVQLYQVGEVRPFYYGLCTPCHAPTNYSRWVNLPEES--LLRPAYVVPWRDPWEPFYVAGGKVPTFDERFRQYGFNRISQACELHVAGFNFEVLNEGFLVHKGFKEALKFHPQKEAENQRNKILYRQFKQELKAKYPNSPHRC", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "L7YAI7-1", "uniprot_id": "B4GA1_DANRE", "id": "L7YAI7-1", "name": "Beta-1,4-glucuronyltransferase 1", "aln": "--MHFSKKCSVFKVVLSALLIVALLQLLYLSFLSKLHGKQQRYKYSELFGSKKNANQGEKNPRREHLRYSLSTGGIFDGSGQYRVYKNLIKSDFSTNQKPGADPRSHHLALATHTTINNLHHLESLLERWKNPISVAIFAN-GEDVKFATAIIYALSLFCPQVQALVDFHLVCHSGEMATFPDQDREHFVGLQEMGCPAVFAKLESHRDKYKNYAIGSNVSYPNNLLRNVARGGTDAAYILVIDIDMIPSANLHHQFVTMLMKREPAADEVLVLPAFEIRHIRKMPASKPELVQLYQVGEVRPFYDELCSRCQAPTNYSLWVNLASKSSGPLEVSYTINWVDPWEPFYIGARSVPLYDESFRQYGFNRISQACELHIAGYRFSVVSNAFLLHKGFKVQGEFHSRKDEENRKNRILFRSFKESLKAKYPTSPRRC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: :*:.::::*:**::**:*******:** ***:::: :* *:* .. .: : : :** :*::**::*.**:****:.*:*: :..*: : ****::::** **..*****:.*:**::** *:.::**.: **** .**:::* * :**** * *:.** . ..* . * ** ** : ***:*:* *********:** * * ****:**:** .* : : ** : : . .**:******: *:** .* **:************ **: *:****** ****..:: *. :*.: * *******:.. .** :** ****************:**: *.*:.:.**:***** :**.:*: **::*:**:*.**:.***:** **::*", "identical_positions": 208, "similar_positions": 126, "identity": "47.93%" }, { "cls_id": "homologset.oma.817657", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P7A1-1", "uniprot_id": "LARG2_RAT", "id": "Q6P7A1-1", "name": "Xylosyl- and glucuronyltransferase LARGE2", "aln": "MLPRGRPRALG-AALLLLLLLV-VGFFLFGRDPEYG----------------------------------------------------------LGTTATLDGDP------YGSRNRSTSSLQLLLPPKCEM------LHVAIVCAGYNSSREIITLMKSVLFYRKNPLHLHLITDAVARNILETLFRTWMVPAVVVSFYDAEELKPLVSWIPNKHYSGLYGLMKLVLPSVLPLSLARVIVLDTDVTFSSDIMELWALFGHFSDKQVVGLVENQSDWYLGNLWKNHRPWPALGRGFNTGVILLWLDRLQQIGWEQMWKLTAKRELLTLTATSLADQDIFNAVIKEHPELVHPLPCVWNVQLSDHTLAERCYLEAADLKVIHWNSPKKLRVKNKHAEFFRDLHLTFLGFDGKLLCRELFGCPNQFPPGVEQLQQALAQLDEEEPCFEFRQQQLTVHRVHITFLSHQ-PPPPRPHDVTLVAQLSMDRLQMLEALCRHWRGPMSLALYLTDAEAQQFLRFVETSPVLSARKDVAYHVVYRDGPLYPVNQLRNVALAQALTPYVFLSDIDFLPAYSLYDYLRASIEQLALGRRQRKAALVVPAFETLHYRFSFPNSKAELLTLLDAGSLHTFRYHEWPQGHASTDYTRWREAQAPYRVQWSADYEPYVVVPRDCPRYDPRFVGFGWNKVAHIIELDAQEYEFLVLPEAFSIHLPHAPSLDISRFRSSPTYRDCLQALKEEFHQDLSRRYGSAALKYLTALQQSRSRA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5XPT3-1", "uniprot_id": "LARG2_MOUSE", "id": "Q5XPT3-1", "name": "Xylosyl- and glucuronyltransferase LARGE2", "aln": "MLPRGRPRAMGAAVLLLLLLLV-VGFFLFGRDPDYG----------------------------------------------------------LGTTATLDEDP------YRSRNLSASSPQLLLPPKCEM------LHVAIVCAGYNSSREIITLTKSLLFYRKNPLHLHLITDAVARNILETLFRTWMVPAVVVSFYDAEELKPLVSWIPNKHYSGLYGLMKLVLPSILPPSLARVIVLDTDVTFSSDIVELWALFDHFSDKQVVGLVENQSDWYLGNLWKNHRPWPALGRGFNTGVILLWLDRLQQTGWEQMWKVTAKRELLTLMATSLADQDIFNAVIKEHPHLVHPLPCVWNVQLSDHTRAERCYLEAADLKVIHWNSPKKLRVKNKHAEFFRNLHLTFLGYDGKLLRRELFGCPNQFPPGAEQLQQALTQLDEEEPCFEFRQQQLTVHRVHITFLPHQ-PPPPQPHDVTLVAQLSMDRLQMLEALCRHWPGPMSLALYLTDEEAQQFLHFVETSPVLSMRKDVAYHVVYRDGPLYPVNQLRNVALAQALTPYVFLSDIDFLPAYSLYDYLRASIEQLELDSR-RKTALVVPAFETLHYRFSFPNSKAELLTLLDAGSLHTFRYHEWPQGHSSTDYSRWREAQAPYSVQWSADYEPYVVVPRDCPRYDPRFVGFGWNKVAHIIELDAQEYEFLVLPEAFSIHLPHAPSLDISRFRSSPTYRNCLQALKEEFHQDLSRRYGSAALKYLTALQQARSRA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A9J7JZU2-1", "uniprot_id": "A0A9J7JZU2_CRIGR", "id": "A0A9J7JZU2-1", "name": "", "aln": "MLPRGRPRALGAVTLLLLLLLL-VGFFLFGRDPEYG----------------------------------------------------------LRAAATLDGDL------YGSRNRSAASLQPLLPPKCEVGVPPQLLHVAIVCAGYNSSREVITLVKSLLFYRKNPLHLHLVTDAIARNILETLFRTWMVPAVVIRFYDAEELKPLISWIPNKHYSGLYGLMKLVLPSILPLSLARVIVLDTDVTFSSDIAELWALFAHFSDKQVVGLVENQSDWYLGNLWKNHRPWPALGRGFNTGVILLWLDRLRQTGWEQMWKLIAKQELLTLMATSLADQDVFNAVIKEHPELVHPLPCVWNVQLSDHTLAERCYLEAADLKVIHWNSPKKLRVKNKHAEFFRNLHLTFLGYDGKLLRRELFGCPNQLPPGAEQLQQALAQLDEEEPCFEFRQQQLSVHRVHITFLPHQ-PPPPRPHDVTLVAQLSMDRLQMLEALCRHWPGPMSLALYLTDAEAQQFLHFVETSPVLSARKDVAYHIVYREGPLYPVNQLRNVALAQALTPYVFLSDIDFLPAYSLYDYLRASIEQLELGSQ-RKAALVVPAFETLHYRLSFPNSKAELLTLLDAGSLYTFRYHEWPQGHAPTDYARWREAKAPYHVQWAADYEPYVVVPRDCPRYDPRFVGFGWNKVAHIIELDAQEYELLVLPEAFSIHLPHAPSLDISRFRSSPTYRHCLQTLKEEFHQDLSRRYGAAALKYLTALQQSQSRA--", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q8N3Y3-1", "uniprot_id": "LARG2_HUMAN", "id": "Q8N3Y3-1", "name": "Xylosyl- and glucuronyltransferase LARGE2", "aln": "MLPRGRPRALGAAALLLLLLLL--GFLLFGGDLGCERREPGGRAGAPGCFPGPLM-------------------------------PRVPPDGRLRRAAALDGDPGA---GPGDHNRSDCGPQPPPPPKCEL------LHVAIVCAGHNSSRDVITLVKSMLFYRKNPLHLHLVTDAVARNILETLFHTWMVPAVRVSFYHADQLKPQVSWIPNKHYSGLYGLMKLVLPSALPAELARVIVLDTDVTFASDISELWALFAHFSDTQAIGLVENQSDWYLGNLWKNHRPWPALGRGFNTGVILLRLDRLRQAGWEQMWRLTARRELLSLPATSLADQDIFNAVIKEHPGLVQRLPCVWNVQLSDHTLAERCYSEASDLKVIHWNSPKKLRVKNKHVEFFRNFYLTFLEYDGNLLRRELFVCPSQPPPGAEQLQQALAQLDEEDPCFEFRQQQLTVHRVHVTFLPHE-PPPPRPHDVTLVAQLSMDRLQMLEALCRHWPGPMSLALYLTDAEAQQFLHFVEASPVLAARQDVAYHVVYREGPLYPVNQLRNVALAQALTPYVFLSDIDFLPAYSLYDYLRASIEQLGLGSR-RKAALVVPAFETLRYRFSFPHSKVELLALLDAGTLYTFRYHEWPRGHAPTDYARWREAQAPYRVQWAANYEPYVVVPRDCPRYDPRFVGFGWNKVAHIVELDAQEYELLVLPEAFTIHLPHAPSLDISRFRSSPTYRDCLQALKDEFHQDLSRHHGAAALKYLPALQQPQSPARG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1SI95-1", "uniprot_id": "F1SI95_PIG", "id": "F1SI95-1", "name": "", "aln": "MLPRGRPRALGAAALLLLLLLLLIGFFLFGGDLDYGRLRPLG-------------------------------------------------------AVALDRDPPA---DHGGHNRSDCVPPRPLPPKCEL------LQVAIVCAGHNSSRDVITLVKSMLFYRKNPLHLHLVTDAVARNILETLFHTWMVPAVRVSFYDADELKPQVSWIPNKHYSGLYGLMKLVLPGALPPDLARVIVLDTDVTFASNIAELWALFAHFSDKQVIGLVENQSDWYLGNLWRNHRPWPALGRGFNTGVILLRLDRLRQAGWEQMWKLIATQELLTLPATSLADQDIFNAVIKEHPWLVQPLPCVWNVQLSDHTLAERCYSEASDLKVIHWNSPKKLRVKNKHVESFRNLHLTFLEYDGNLLRRELFGCPCPPPPGAEQLQRALAQLDEEDACFEFRQQQLTVHRVHITFLPHK-PPPPQPYDVTLVAQLSMDRLQMLEALCRHWPGPMSLALYLTDAEAQQFLRFVETSAVLSARQNVAYHVVYREGPLYPINQLRNVALAQALTPYVFLSDIDFLPAYSLYHYLRASIEQLELGTGGRKVALVVPAFETLHYRFSFPSSKAELLALLDAGSLYTFRYHEWPRGHAPTDYARWREAQAPYRVQWAADYEPYVVVPRDCPRYDPRFVGFGWNKVAHIVELDAQEYELLVLPEAFIIHLPHAPSLDISRFRSSPTYRDCLQALKDEFHQDLSRHYGAAALKYLTALQQPRGPT--", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q66PG1-1", "uniprot_id": "LARG2_DANRE", "id": "Q66PG1-1", "name": "Xylosyl- and glucuronyltransferase LARGE2s", "aln": "MLCPCRGKLKLLVVSLSFVILF-TWLYLLVGNSENGRSLLLSACLVESTEARLLERDVLASRVREVEEENRQIRLQLSQSQGLAGQPAEGNYGNQQWVASADTGPEDVENTAEERANHSECSRSPTAEKCEL------LHVACVCAGHNASRDVVTLVKSILFHRRNPLHFHFITDTVANQILSTLFQSWMVPSVQVSFYDADELKSEVSWIPNKHYSGIYGLMKLTLTKALPSNLSKVIVLDTDITFATDIAELWAIFRKFTEKQVIGLVENQSDWYLGNLWKNHKPWPALGRGFNTGVILLYLERLRRMGWEQMWRLTAERELMSMLSTSLADQDIFNAFIKQNPVLVHQLPCFWNVQLSDHTRSEQCYTEVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCPSQASSESTVLQQALEELDEDDQCYDFRRERIMLHRVHLYFLQYEYSPTDDGTDITLVAQLSMDRLQMLEAICKHWEGPISLALYMSDAEAQQFLRYAQASEVLKNRKNVGYHIVYKEGQFYPVNLVRNVALRNVNTPYVFLTDVDFLPMYGLYDYLRKSIVQLDMANT--KKALVVPAFETLRYRLSFPKSKAELLSMLDMGTLYTFRYHVWTKGHAPTNYAKWRTATTPYKVEWEADFEPYVVVRRDCPEYDQRFVGFGWNKVSHIMELDAQEYDLIVLPNAFMIHMPHAPSFDISKFRSSPSYRYCLTTLKDEFHQDLSRKYGSAALKYLTAQRNI------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1NX24-1", "uniprot_id": "F1NX24_CHICK", "id": "F1NX24-1", "name": "", "aln": "MLCSWRVKLKLLLATITLAVLL-SWLYLFVGSLEYGRFLLLPPCLGE-QPSRDVEREALASQVRRVEEENQQLRMQLGQVQ------AEGSDGNPQWAASAEDGPP----LGGERNNRTACPKQRMVRKCEL------LHVAIVCAGHNASRDVVTLVKSILFHRKNPLHFHFITDSVAHQILQTLFQSWMVPSIHVSFYNADDLKPEVSWIPNKHYSGIYGLMKLTLTKALPSNLSKVIVLDTDITFATDIAELWAVFGKFSEKQVIGLVENQSDWYLGNLWKNHKPWPALGRGFNTGVILLLLDRLRRLGWEQMWRLTAERELMSMLSTSLADQDIFNAVIKQNPALVYRLPCFWNVQLSDHTRSELCYTEVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCASLPSPPSDQLQQALEELDEDDPCYDFRRQHLTQHRVHLFFLQYEFLALPNPTDVTLVAQLSMDRLQMLEAICKHWAGPISLALYMSDAEAQQFLRYAQASEVLSARRNVAYHIVYKEGQFYPINLLRNVALANTQTPYVFLTDIDFLPMYGLYDYLRNSIQQLELPHR--KAALIVPAFETLHYRLTFPKSKAELLSMLDMGSLYTFRYHVWPKGHAPTDYAKWRTATVPYRVAWQPDFEPYVVVRRDCPKYDQRFVGFGWNKVSHIMELDAQEYELLVLPNAFMIHMPHAPSFDISKFRLSAGYRGCLQTLREEFHQDLSRKYGAAALKYLTAERNL------", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * : . : : :*. : *: . ..: : . : ***: *:** ****:*:**:::** **:**:*:****:*::**::*.:**.***::****:: : **.*::**. :**********:******.*. ** .*::*******:**:::* ****:* :*::.*.:***************:**:**************** *:**:: ******:: * :**::: :*******:***.**::* ** ***.********* :* ** *.:*******************.* **:::**** :**:** **** *. .. **:** :***:: *::**:::: ****: ** :: . *:****************:*:** **:*****::* ******::.::* ** *::*.**:**::* :**:* :***** :. ******:*:**** *.**.*** ** ** : * **:*******:**::** **.***::** *:*:***** *.:**:.*:*::** * .** * * .::****** ****.** **********:**:*******:::***:** **:*****:***:** *. ** ** :*::********::*:******.* :: ", "identical_positions": 394, "similar_positions": 170, "identity": "51.5%" }, { "cls_id": "homologset.oma.817661", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "L7YAI7-1", "uniprot_id": "B4GA1_DANRE", "id": "L7YAI7-1", "name": "Beta-1,4-glucuronyltransferase 1", "aln": "--MHFSKKCSVFKVVLSALLIVALLQLLYLSFLSKLHGKQQRYKYSELFGSKKNANQGEKNPRREHLRYSLSTGGIFDGSGQYRVYKNLIKSDFSTNQKPGADPRSHHLALATHTTINNLHHLESLLERWKNPISVAIFAN-GEDVKFATAIIYALSLFCPQVQALVDFHLVCHSGEMATFPDQDREHFVGLQEMGCPAVFAKLESHRDKYKNYAIGSNVSYPNNLLRNVARGGTDAAYILVIDIDMIPSANLHHQFVTMLMKREPAADEVLVLPAFEIRHIRKMPASKPELVQLYQVGEVRPFYDELCSRCQAPTNYSLWVNLASKSSGPLEVSYTINWVDPWEPFYIGARSVPLYDESFRQYGFNRISQACELHIAGYRFSVVSNAFLLHKGFKVQGEFHSRKDEENRKNRILFRSFKESLKAKYPTSPRRC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BWP8-1", "uniprot_id": "B4GA1_MOUSE", "id": "Q8BWP8-1", "name": "Beta-1,4-glucuronyltransferase 1", "aln": "MQMSYAIRCAFYQLLLAALMLVAMLQLLYLSLLSGLHGQEEQEQYFEFFPPSPRSVDQVKS----QLRTALASGGVLDASGDYRVYRGLLKTTMDPND----------VILATHASVDNLLHLSGLLERWEGPLSVSVFAATKEEAQLATVLAYALSSHCPEMRARVAMHLVCPSRYEAAVPDPREPGEFALLRS-CQEVFDKLARVAQPGINYALGTNTSYPNNLLRNLAR--EEANYALVIDVDMVPSEGLWRGLREMLDQSNHWDGTALVVPAFEIRRSRRMPMNKNELVQLYQVGEVRPFYYGLCTPCHAPTNYSRWVNLPEES--LLRPAYVVPWRDPWEPFYVAGGKVPTFDERFRQYGFNRISQACELHVAGFNFEVLNEGFLVHKGFKEALKFHPQKEAENQRNKILYRQFKQELKARYPNSPHRC", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: :*:.::::*:**::**:*******:** ***:::: :* *:* .. .: : *. :** :*::**::*.**:****:.*:*: :..*: : ****::::** **..*****:.*:**::** *:.::**.: **** .**:::* * :**** * *:.** . ..* . * ** ** : ***:*:*.*********:** :* * ****:**:** .* : : ** : : . .**:******: *:** .* *************** **: *:****** ****..:* *. :*.: * *******:.. .** :** ****************:**:.*.*:.:.**:***** :**.:*: **::*:**:*.**:.***:**.**:**", "identical_positions": 212, "similar_positions": 127, "identity": "48.85%" }, { "cls_id": "homologset.oma.817692", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K618-1", "uniprot_id": "A0A0G2K618_RAT", "id": "A0A0G2K618-1", "name": "", "aln": "MLGICRGRRKFLAASLTLLCIPALTWIYLFAGSLEDGKPVSLSPLESQAHSPRYTASSQRERESLEVRVREVEEENRALRRQLS------LAQGQSPAHRRGNHSKTYSMEEGTGDSENQRAGIVAGNSSECGQQPAVEKCETIHVAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHLIADSIAEQILATLFQTWMVPAVRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPANLERVIVLDTDITFATDIAELWAVFHKFKGQQVLGLVENQSDWYLGNLWKNHRPWPALGRGYNTGVILLLLDKLRKMKWEQMWRLTAERELMGMLSTSLADQDIFNAVIKQNPFLVYQLPCFWNVQLSDHTRSEQCYRDVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCPSETDVNSENLQKQLSELDEDDLCYEFRRERFTVHRTHLYFLHYEFEPSADHTDVTLVAQLSMDRLQMLEAICKHWEGPISLALYLSDAEAQQFLRYAQGSEVLMSRQNVGYHIVYKEGQFYPVNFLRNVAMKHISTPYMFLSDIDFLPMYGLYEYLRKSVIQLDLANTKKAMIVPAFETLRYRLSFPKSKAELLSMLDMGTLFTFRYHVWTKGHAPTNFAKWRTATTPYQVEWEADFEPYVVVRRDCPEYDRRFVGFGWNKVAHIMELDAQEYEFTVLPNAYMIHMPHAPSFDITKFRSNKQYRVCLKTLKEEFQQDMSRRYGFAALKYLTAENNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1M7-1", "uniprot_id": "LARG1_MOUSE", "id": "Q9Z1M7-1", "name": "Xylosyl- and glucuronyltransferase LARGE1", "aln": "MLGICRGRRKFLAASLTLLCIPAITWIYLFAGSFEDGKPVSLSPLESQAHSPRYTASSQRERESLEVRVREVEEENRALRRQLS------LAQGQSPAHHRGNHSKTYSMEEGTGDSENLRAGIVAGNSSECGQQPAVEKCETIHVAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHLIADSIAEQILATLFQTWMVPAVRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPANLERVIVLDTDITFATDIAELWAVFHKFKGQQVLGLVENQSDWYLGNLWKNHRPWPALGRGYNTGVILLLLDKLRKMKWEQMWRLTAERELMGMLSTSLADQDIFNAVIKQNPFLVYQLPCFWNVQLSDHTRSEQCYRDVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCPSETDVNNENLQKQLSELDEDDLCYEFRRERFTVHRTHLYFLHYEFEPSADNTDVTLVAQLSMDRLQMLEAICKHWEGPISLALYLSDAEAQQFLRYAQGSEVLMSRQNVGYHIVYKEGQFYPVNLLRNVAMKHISTPYMFLSDIDFLPMYGLYEYLRKSVIQLDLANTKKAMIVPAFETLRYRLSFPKSKAELLSMLDMGTLFTFRYHVWTKGHAPTNFAKWRTATTPYQVEWEADFEPYVVVRRDCPEYDRRFVGFGWNKVAHIMELDAQEYEFTVLPNAYMIHMPHAPSFDITKFRSNKQYRICLKTLKEEFQQDMSRRYGFAALKYLTAENNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3HN56-1", "uniprot_id": "G3HN56_CRIGR", "id": "G3HN56-1", "name": "", "aln": "MLGICRGRRKFLAASLSLLCIPAITWIYLFAGSFEDGKPVSLSPLESQAHSPRYTASSQRDRESLEVRVREVEEENRSLRRQLS------LAQGQVPVHRRGNHSKTYSMEEGTGDSENLRAGIVAGNSSECGQQPAVEKCETIHVAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHLIADSIAEQILATLFQTWMVPAVRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPANLERVIVLDTDITFATDIAELWAVFHKFKGQQVLGLVENQSDWYLGNLWKNHRPWPALGRGYNTGVILLLLDKLRKMKWEQMWRLTAERELMGMLSTSLADQDIFNAVIKQNPFLVYQLPCFWNVQLSDHTRSEQCYRDVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCPSETDVNSENLQKQLSELDEDDLCYEFRRERFTVHRTHLYFLHYEFEPATDNTDVTLVAQLSMDRLQMLEAICKHWEGPISLALYLSDAEAQQFLRYAQGSEVLMSRHNVGYHIVYKEGQFYPVNLLRNVAMKHISTPYMFLSDIDFLPMYGLYEYLRKSVIQLDLANTKKAMIVPAFETLRYRLSFPKSKAELLSMLDMGTLFTFRYHVWTKGHAPTNFAKWRTATMPYRVEWEADFEPYVVVRRDCSEYDRRFVGFGWNKVAHIMELDAQEYEFTVLPNAYMIHMPHAPSFDITKFRSNKQYRICLKTLKEEFQQDMSRRYGFAALKYLTAENNS", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "O95461-1", "uniprot_id": "LARG1_HUMAN", "id": "O95461-1", "name": "Xylosyl- and glucuronyltransferase LARGE1", "aln": "MLGICRGRRKFLAASLSLLCIPAITWIYLFSGSFEDGKPVSLSPLESQAHSPRYTASSQRERESLEVRMREVEEENRALRRQLS------LAQGRAPSHRRGNHSKTYSMEEGTGDSENLRAGIVAGNSSECGQQPVVEKCETIHVAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHLIADSIAEQILATLFQTWMVPAVRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPANLERVIVLDTDITFATDIAELWAVFHKFKGQQVLGLVENQSDWYLGNLWKNHRPWPALGRGYNTGVILLLLDKLRKMKWEQMWRLTAERELMGMLSTSLADQDIFNAVIKQNPFLVYQLPCFWNVQLSDHTRSEQCYRDVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCPSEADVNSENLQKQLSELDEDDLCYEFRRERFTVHRTHLYFLHYEYEPAADSTDVTLVAQLSMDRLQMLEAICKHWEGPISLALYLSDAEAQQFLRYAQGSEVLMSRHNVGYHIVYKEGQFYPVNLLRNVAMKHISTPYMFLSDIDFLPMYGLYEYLRKSVIQLDLANTKKAMIVPAFETLRYRLSFPKSKAELLSMLDMGTLFTFRYHVWTKGHAPTNFAKWRTATTPYRVEWEADFEPYVVVRRDCPEYDRRFVGFGWNKVAHIMELDVQEYEFIVLPNAYMIHMPHAPSFDITKFRSNKQYRICLKTLKEEFQQDMSRRYGFAALKYLTAENNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1BDI0-1", "uniprot_id": "E1BDI0_BOVIN", "id": "E1BDI0-1", "name": "", "aln": "MLGVCRGRRKFLAASLTLLCIPAITWLYLFAGSFEDGKPVSLSPLEAQPHSPRYTASSQRERESLEVRVREVEEENRALRRQLS------LAQGRSPSHRRGNHSKTYSMEEGTGDSENLHAGIVAGNSSECGQQPVVEKCETIHVAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHLIADSIAEQILATLFQTWMVPAVRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPANLERVIVLDTDITFATDIAELWAVFHKFKGQQVLGLVENQSDWYLGNLWKNHRPWPALGRGYNTGVILLLLDKLRKMKWEQMWRLTAERELMGMLSTSLADQDIFNAVIKQNPFLVYQLPCFWNVQLSDHTRSEQCYRDVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCPSEADVNSENLQKQLSELDEDDLCYEFRRERFTVHRTHLYFLHYEYEPASDNTDVTLVAQLSMDRLQMLEAICKHWEGPVSLALYLSDAEAQQFLRYAQGSEVLMGRHNVAYHIVYKEGQFYPVNLLRNVAMKHVGTPYMFLSDIDFLPMYGLYEYLRKSVIQLDLANTKKAMIVPAFETLRYRLSFPKSKAELLSMLDMGTLFTFRYHVWTKGHAPTNFAKWRTATTPYRVEWEADFEPYVVVRRDCPEYDRRFVGFGWNKVAHIMELDAQEYEFIVLPNAYMIHMPHAPSFDITKFRSNKQYRICLKTLKEEFQQDMSRRYGFAALKYLTAENNS", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A480F6A1-1", "uniprot_id": "A0A480F6A1_PIG", "id": "A0A480F6A1-1", "name": "", "aln": "MLGICRGRRKFLAASLTLLCIPAITWLYLFAGSLEDGKPVSLSPLESQPHSPRYTASSQRDRESLELRMREVEEENRALRRQLS------LAQGR--GHRRGNHSRTYSMEEGTGDSENLRAGIVAGNSSECGQQPVVEKCETIHVAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHLIADSIAEQILATLFQTWMVPAVRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPAKLERVIVLDTDITFATDIAELWAVFHKFKGQQVLGLVENQSDWYLGNLWKNHRPWPALGRGYNTGVILLLLDKLRKMKWEQMWRLTAERELMGMLSTSLADQDIFNAVIKQNPFLVYQLPCFWNVQLSDHTRSEQCYRDVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCPSEADVNSENLQKQLSELDEDDLCYEFRRERFTVHRTHLYFLHYEYEPASDNTDVTLVAQLSMDRLQMLEAICKHWEGPISLALYLSDAEAQQFLRYAQGSEVLMGRHNVAYHIVYKEGQFYPVNLLRNVAMKHVGTPYMFLSDIDFLPMYGLYEYLRKSVIQLDLANTKKAMIVPAFETLRYRLSFPKSKAELLSMLDMGTLFTFRYHVWTKGHAPTNFAKWRTATTPYRVEWEADFEPYVVVRRDCPEYDRRFVGFGWNKVAHIMELDAQEYEFIVLPNAYMIHMPHAPSFDITKFRSNKQYRICLKTLKEEFQQDMSRRYGFAALKYLTAENNS", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q66PG2-1", "uniprot_id": "LARG1_DANRE", "id": "Q66PG2-1", "name": "Xylosyl- and glucuronyltransferase LARGE1", "aln": "MLGMCRGRRKFVAASLALIFIPALTWLYLSSANIT-VKPLPLSPLDPQSSA---VVGAAAEHQSLELRLRDVEEHNNALRREISRTPRVPTHSSHPSSSRHGNQLHTHSTEEGTGDSE-AKKGAAAGNSSDCVPQPVVKKCETIHIAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHIITDSIARKILADLFHTWMVPAVHVNFYDADELKSEVSWIPNKHYSGIHGLMKLVLTKTLPSDLEKVIVLDTDITFATDIAELWVVFHKFKGQQVLGLVENQSDWYLGNLWKNHRPWPALGRGFNTGVILLLLDRLRKLKWEQMWRLTAERELMSMLSTSLADQDIFNAVIKQNPFLVHQLPCYWNVQLSDHTRSEKCYKDVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCPSETDHNSENLQKTLSELDEDDPCYEFRRERFTVHRTHVYFLHYEYEPTVDNTDVTLVAQLSMDRLQMLEAICKHWEGPISLALYLSDAEAQQFLRYAQGSEVLMSRSNVGYHIVYKEGQFYPVNLLRNVAMGQVNTPYMFLSDIDFLPMYGLYEYLRKSVVQLDMGNTKKALVVPAFETLRYRLSFPKSKAELLSQLDMGTLFTFRYHVWTKGHAPTDFAKWRTATTPYRVQWEADFEPYVMVRRESPEYDRRFVGFGWNKVAHIMELDAQEYEFVVLPNAYMIHMPHAPSFDITKFRSNKQYRACLKTLKEEFQQNMSRRYGFAALKYMTVDNNS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*******:****:*: ***:**:** :..: **:.****:.*. : ...: :::***:*:*:***.*.:***::* ..: ::**: :*:* ******** : * .*****:* **.*:******:*******************************:*:****.:*** **:*******:*:**:*******************:************:.**:******************.**************************************:**********:***:***************.***********************:****:************:**:***************************************************:* *.***** ******** ***************:******:**: * ***************************:*************************.* **.**************:****** ::.*************************:***:.*****::********************** *********************:******** **:*:*********:***:..*********************.***** **************************** ***********:************:*.:***", "identical_positions": 624, "similar_positions": 95, "identity": "81.89%" }, { "cls_id": "homologset.oma.817713", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A4X1UF97-1", "uniprot_id": "A0A4X1UF97_PIG", "id": "A0A4X1UF97-1", "name": "", "aln": "MSISAHTRKTNKKNSPLESILMPQVPRSNYLHLQEEKQRLQLKKFLLHRIFLVAKITANMEKKDIAEYYEQVFQSILKRHLGEAVTGLLLIYPTSILHILESSNDTLYQILSDYLNHEKDEVEFFIQGMKIIVTSHNIPTRLFMQWYISVIKAPVMYLDDVTQSQSLQEVITEFLIQTHKLALHIFKTVKVGTKGPGDNLHQIAPDLLLPEQIIKYLCNSEEFMDPETFINLYNKPIHVTLDSEVVWPAPSRF", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "F1MDK7-1", "uniprot_id": "F1MDK7_BOVIN", "id": "F1MDK7-1", "name": "", "aln": "MSFGTHPRKTNKKNLPLES-LMPQVPRSNYLQFQEEKQRLQLKKFLLHRMFLVARITANIEKKDIADYYEQLFQSILKRHLGEAVTGLLLIYPTSILHILESSSGTFYQILLDYLSHKKDEMEFFIQGMKIIVMSHNIPTRLFMQWHVSVIKAPVMYLDDVTQTQSLQEVMMEFLIQTHKLALHLFKTVKVSPKGPGDSLHQAAPELLLPEQIIKYLCNSAELMDPEGFINMYNKPIHVTLDSEVVWPAPSRF", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q8TBZ9-1", "uniprot_id": "TEX47_HUMAN", "id": "Q8TBZ9-1", "name": "Testis-expressed protein 47", "aln": "MSFSVHNQKGSKRPLPLEPLLFLQVPRSNYLHFQEEKQRLHLKKFLLDRMFLVAKIQANVERKDVADYYEQMFQSVLKHHLGEAVTGLLLIYPTSILHILESSSDTLYKVLLDYIGHVKDETVFFIQQMKIIVISHNIPMRLFMQWHVSVIKVPVMYLDDVTQSQSLKEVITDFLTQTHKLSLYLCQTMKVGTKGPGDNLHQVAPDLLLPEQIIKYLCKSEEFMDPATFINMYNRPIHITLDSEVVWPAPSRF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0JPP5-1", "uniprot_id": "TEX47_RAT", "id": "A0JPP5-1", "name": "Testis-expressed protein 47", "aln": "MSFIVHNRRSSKKQFQVDPLLMPKVPRINYLHIQEEKHRLQLKKFLLHRLFLVGYIQANTEKKEISEYYEQLFQSILKHHLGEVVTGLFLIYPSSFLHILESSNGTLFRILLDYVAHEKSEREFMIQNMKIIVASHNIPTRLFMQWHISIIKVPVLYLDDDTQSQSVEEVTTDFLTLTHKLALHLYKTVKLGGKGPGDNLHQLAPELILPEKTIKYLCKATEFMDPASFLSMYNRPIHITMDSDIVWPAPSRF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D5W8-1", "uniprot_id": "TEX47_MOUSE", "id": "Q9D5W8-1", "name": "Testis-expressed protein 47", "aln": "MSFMVHNRKGSKKQFQVDPLLLPKVPRTNYLHLQEEKHRLQLKKFLLHRMFLVGYIQGNTEKKDISEYYEQLFQSILKHHLGESVTGLMLIYPSTFLHILESSNGTLFRILLDYVAHEKSETEFMLQNMKIVVASHNIPTRLFMQWHISAIKVPVLYLDDESQSPSIEEVTTEFLTMTHKLALQLYKTVKLGAKGPGDNLHQLAPELILPEQIIKYLCKAEEFMDPASFLSMYNRPIHVTLDSDIVWPAPSRF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8C2QE39-1", "uniprot_id": "A0A8C2QE39_CRIGR", "id": "A0A8C2QE39-1", "name": "", "aln": "MSFMVHTRKGSKKHYHVDPLLMPKVPRINYMHLQEEKHRLQLKKFLLHRMFLVGHIQENVEKKEISEYYEQLFQSILKHHLGEAVTGILLIYSSTFLHIMETSNGTFFRILLDYVAHEKEENEFMIYNMKIIVASHNIPTRLFMQWHISVIKVPVLYLEDVTQSQSLAEVTTDFLTMTHKLSLHLFKTIKVGMKGPGDNLHQIAPDLLLPEQTIQYLCKADEFLDPVTFLSMYNKPIHVTLDSEIVWPAPSRF", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: .* :: .*: ::. *: :*** **:::****:**:******.*:***. * * *:*::::****:***:**:**** ***::***.:::***:*:*..*::::* **: * *.* *:: ***:* ***** ******::* **.**:**:* :*: *: ** :** ****:* : :*:*:. *****.*** **:*:***: *:***:: *::** *:.:**:***:*:**::********", "identical_positions": 136, "similar_positions": 78, "identity": "53.75%" }, { "cls_id": "homologset.oma.817808", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AT69-1", "uniprot_id": "A0A8I6AT69_RAT", "id": "A0A8I6AT69-1", "name": "Sorting nexin-14", "aln": "MWLRRRGLGVPSASASEGGKSSASWTEMGSWVRTIGERLKQRLR-LDVGREICRQYPLFCFLLLCLSAASLLLNRYLHVLMIFWSFVAGVVTFYCSLGPDSLLPNIFFTIKYKPKQLGLQELFPQGHSCAVCGKVKCKRHRPSLLLENYQPWLDLKVSSKVDASLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLVRRIHKVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEYLQQAALEEYGPDLHVALRSRRDELQYLRKLTELLFPYILPPKATDCRSLTLLIREILSGSVFLPSLDFLADPDTVNHLLIIFIDDSPPEKATEPASPLVPFLQKFAEPRNKKPSVLKLELKQIREQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESPTRNSKFNRGSLSLDDFRSTQKRGESFGISRIGSKIKGVFKSTTMEGAVLPSYGVAEGEDDFIEEGIVVLEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKERIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGTFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLVQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQHLEPFIMSFINSCESPKPKPSRPELTILSPTSENNKKLFNDLFKNNANRAENTERKQNQNYFMEVMTVDGVYDYLMYVGRVVFQVPDWLHHLLMGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLIVKCIGEETKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPELNKLFISVTLGRPVSHGGATGRTWEPFIAQRPPCLPEVRVATEDTQHHIACHV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BHY8-1", "uniprot_id": "SNX14_MOUSE", "id": "Q8BHY8-1", "name": "Sorting nexin-14", "aln": "MWLRRRGLGVPSASASEGGTSSPAWTEMGSWVRTICGRLKQRLR-LDVGREICRQYPLFCFLLLCLSVASLLLNRYLHVLMIFWSFVAGVVTFYCSLGPDSLLPNIFFTIKYKPKQLGLQELFPQGHSCAVCGKVKCKRHRPSLLLENYQPWLDLKVSSKVDASLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLVRRIHKVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEYLQQAALEEYGPELHVALRSRRDELQYLRKLTELLFPYILPPKATDCRSLTLLIREILSGSVLLPSLDFLADPDTVNHLLIIFIDDSPPEKATEPASPLVPFLQKFAEPRNKKPSVLKLELKQIREQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESPTRNSKFN---------RSTQKRGESFGISRIGSKIKGVFKSTTMEGAVLPNYGVAEGEDDFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKERIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGTFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLVQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQHLEPFIMSFINSCESPKPKPSRPELTILSPTSENNKKLFNDLFKNNANRAENTERKQNQNYFMEVMTVDGVYDYLMYVGRVVFQVPDWLHHLLMGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLIVKCIGEETKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPELNKVQKEATS----------MTSWM----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5W7-1", "uniprot_id": "SNX14_HUMAN", "id": "Q9Y5W7-1", "name": "Sorting nexin-14", "aln": "---------------------------MVPWVRTMGQKLKQRLR-LDVGREICRQYPLFCFLLLCLSAASLLLNRYIHILMIFWSFVAGVVTFYCSLGPDSLLPNIFFTIKYKPKQLGLQELFPQGHSCAVCGKVKCKRHRPSLLLENYQPWLDLKISSKVDASLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLIRRIHKVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEFLQQAALEEYGPELHVALRSRRDELHYLRKLTELLFPYILPPKATDCRSLTLLIREILSGSVFLPSLDFLADPDTVNHLLIIFIDDSPPEKATEPASPLVPFLQKFAEPRNKKPSVLKLELKQIREQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESPTRNSKLNRGSLSLDDFRNTQKRGESFGISRIGSKIKGVFKSTTMEGAMLPNYGVAEGEDDFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKERIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQHLEPFIMNFINSCESPKPKPSRPELTILSPTSENNKKLFNDLFKNNANRAENTERKQNQNYFMEVMTVEGVYDYLMYVGRVVFQVPDWLHHLLMGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLLVKCIGEETKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPELNKVQKEVTS----------VTSWM----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0XLS9-1", "uniprot_id": "A0A8V0XLS9_CHICK", "id": "A0A8V0XLS9-1", "name": "Sorting nexin-14", "aln": "---------------------------MG-WLRAAGERLRQRVRGAEALRETCRQYPLFCCLLLGLAAATLLLNRYLHVLMIFWSFVAGVVTFYCSLGPDSLLPNILYTIKYKPKQLELPELFPHGHSCAVCGKVKCKRHRPALLLENYQPWLDLKVPSKVDASLSEVLELVLENFIYPWYRNITDDESSVDELRGTLRFFASVLVRRIHKVDIPTVVTKKMLKAAMKHIEVIAKARQKVKNAEFLQQAALEEYGPELHVALRSRRDELHYLRKLTELLFPYILPPKSTECRSLALLIREILPGSVFLPSMDFLADPDTVNHLLLIFIDDSPPEKATEPTSSLVPFLQKFAEPRNKKPSVLKLELKEIRDQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSDTEKMALHEEVQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYEDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRHLLRGAESPTRNSKFNRSSLSLDDFRTTQKRGESFGISRIGNKIKGVFKSSAMEGAMLPNYNLNDGEDDFIEEGVMVMEDDSPEEAVSTPNTPRNLSAWKISIPYVDFFDDPSLERKDRKERIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGTFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKMLPDVNLGKIIKSVPGKLMKEKGQHLEPFIMNFINSCESPKPKPSRPELTILSPTSENNKKLFNDLFKNNANRSENTERRQNQNYFMEMMTVEGVYDYLLYVGRVVFHIPDWLHHLLMGGRILFKNTLELYTDYYLHYKLEQLCEEHRLVSLITLLRDAVFCENTEPRSVQDKQKRAKQTFEEMMRYIPDLIGKCIGEEAKYEGIRLLFDGMQQPVLNKQLTYVLLDIGIQELFPELSKGPKEASS----------AACWM----------------------------", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:*: :*:**:* :. ** ******** *** *:.*:******:*:***************************::********* * ****:*****************:*************:.******************:*****::***** ***** *********:*********:::***:***********.********:*:***********:************:*****************:*:****:*******.***:***:*************:**************:*.************************:**:****************************************: * ::****:********************************** **************************************:*************:* *.**************.********::****:**.*.: :*********::*:***** ************:************:*** ***::***********************************************:**********************************:***************************:******************************.*****************************************:*****:********:***:******:*******::********** *********:******: ***** :**************:*********:***** *********.*****: ******:***.*******:**************** ********.* ..: * ", "identical_positions": 814, "similar_positions": 89, "identity": "80.43%" }, { "cls_id": "homologset.oma.817831", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZKD3-1", "uniprot_id": "ALKB5_RAT", "id": "D3ZKD3-1", "name": "RNA demethylase ALKBH5", "aln": "MAAASGYTDLREKLKSMTSRDNYKAGSREAAAAAAAAVAAAAAAAAAAEPYPVSGTTKRKYQEDSDPERSDYEEHQLQKEEEARKVKSGIRQIRLFSQDECSKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKYFFGEGYTYGAQLQKRGPGQERLYPPGDVDEIPEWVHQLVIQKLVEHRVIPEGFVNSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFGCKFQFKPIRVSEPVLSLPVRRGSVTVLSGYAADEITHCIRPQDIKERRAVIILRKTRLDAPRLETKSLSSSTLPPSYASDRLSGNTRDPALKPKRSHRKADPDAAHRPRILEMDKEENRRSVLLPTHRRRGSFSSENYWRKSYESSEDCP--EAASSPTRKVKMRRH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TSG4-1", "uniprot_id": "ALKB5_MOUSE", "id": "Q3TSG4-1", "name": "RNA demethylase ALKBH5", "aln": "MAAASGYTDLREKLKSMTSRDNYKAGSREAAAAAAAAVAAAAAAAAAAEPYPASGTTKRKYQEDSDPERSDYEEHQLQKEEEARKVKSGIRQIRLFSQDECSKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKYFFGEGYTYGAQLQKRGPGQERLYPPGDVDEIPDWVHQLVIQKLVEHRVIPEGFVNSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFGCKFQFKPIRVSEPVLSLPVRRGSVTVLSGYAADEITHCIRPQDIKERRAVIILRKTRLDAPRLETKSLSSSTLPPSYASDRLSGNTRDPALKPKRSHRKADPDAAHRPRILEMDKEENRRSVLLPTHRRRGSFSSENYWRKSYESSEDCP--EAASSPTRKVKMRRH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P6C2-2", "uniprot_id": "ALKB5_HUMAN", "id": "Q6P6C2-2", "name": "RNA demethylase ALKBH5", "aln": "MAAASGYTDLREKLKSMTSRDNYKAGSREAAAAAAAAVAAAAAAAAAAEPYPVSG-AKRKYQEDSDPERSDYEEQQLQKEEEARKVKSGIRQMRLFSQDECAKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKYFFGEGYTYGAQLQKRGPGQERLYPPGDVDEIPEWVHQLVIQKLVEHRVIPEGFVNSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFGCKFQFKPIRVSEPVLSLPVRRGSVTVLSGYAADEITHCIRPQDIKERRAVIILRKTRLDAPRLETKSLSSSVLPPSYASDRLSGNNRDPALKPKRSHRKADPDAAHRPRILEMDKEENRRSVLLPTHRRRGSFSSENYWRKSYESSEDCS--EAAGSPARKVKMRRH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1BH29-1", "uniprot_id": "ALKB5_BOVIN", "id": "E1BH29-1", "name": "RNA demethylase ALKBH5", "aln": "MAAASGYTDLREKLKSMTSRDNYKAGSREAAAAAAAAVAAAAAAAAAAEPYAAPG-VKRKYPEDSDPERSDFEEQQLQKEEEARKVKSGIRQMRLFSQDECAKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKYFFGEGYTYGAQLQKRGPGQERLYPPGDVDEIPEWVHQLVIQKLVEHRVIPEGFVNSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFGCKFQFKPIRVSEPVLSLPVRRGSVTVLSGYAADEITHCIRPQDIKERRAVIILRKTRLDAPRLETKSLSSSVLPPSYASDRLSGNNRDPALKPKRSHRKADPDAAHRPRILEMDKEENRRSVLLPAHRRAGRFSSENYRRKSYEPGEDCS--EAAGSPARKVKMRRH", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A287A496-1", "uniprot_id": "A0A287A496_PIG", "id": "A0A287A496-1", "name": "RNA demethylase ALKBH5", "aln": "MAAASGYTDLREKLKSMTSRDNYKAGSREAAAAAAAAVAAAAAAAAAAEPYAAPG-AKRKYQEDSDPERSDFEEQQLQKEEEARKVKSGIRQMRLFSQDECAKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKYFFGEGYTYGAQLQKRGPGQERLYPPGDVDEIPEWVHQLVIQKLVEHRVIPEGFVNSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFGCKFQFKPIRVSEPVLSLPVRRGSVTVLSGYAADEITHCIRPQDIKERRAVIILRKTRLDAPRLETKSLSSSVVAPSYASDRLSGNSRDPALKPKRSHRKADPDAAHRPRILEMDKEENRRSVLLPAHRRGGSLSSQDHWRKSYEPGEDCS--EAAGSPARKVKMRRH", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "F1NIA5-1", "uniprot_id": "F1NIA5_CHICK", "id": "F1NIA5-1", "name": "RNA demethylase ALKBH5", "aln": "-MAGSGYTDLREKLKSMMP---YRDGSK-----------------GPREPPEPPYERKRRYHEDSGSEHSDYEEQ--KEEEEARKVKSGIRQLRLFSAEECAKIEARIDDVVSRAEKGLYKEHTVDRAPLRNKYFFGEGYTYGSQLQRRGPGQERLYPRGEVDAIPEWVHDLVIRKLVEHRVIPEGFVNSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFGCKFQFKPIRVSEPVLFLPVKRGSVTVLSGYAADEITHCIRPQDIKERRAVIILRKTRLDAPRLETKSLSSSVLPPGYTSDRLSGSNRDQILKPKRSHRKADPDAAHRPRILEMDKEENRRSVLLPKHRRRSNFSSENYWRRSYEYTEDCDEEEEDGSPARKVKMRRH", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q08BA6-1", "uniprot_id": "ALKB5_DANRE", "id": "Q08BA6-1", "name": "RNA demethylase ALKBH5", "aln": "---MAGFTDLREKLKSMTP--------------------------HRDKVFEYSNGEKRKYRE-SDDDESEYEER---RDAEARRVKSGIKQASIFTLEECARIEAKIDEVVAKADKGLYREHTVDRAPLRNKYFFGEGYTYGAQLEKRGPGQERLYSKGEVDDIPDWVHELVIDRLVTHGVIPEGFVNSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFGCKFLFKPIRVSEPVLHLPVRRGSVTVLSGYAADDITHCIRPQDIKERRAVIILRKTRADAPRLDSNSLSPSIVSP----------KRRHILKAKRSHRKADPDAAHRPRVLEMDKELQRRS-LSSRQRRHDDGSSENSWRRADD-REPAARYTHDHAPTRRVKMRRH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:********** . : . **:* * *. :.*::**: .: ***:*****:* :*: :**::***:**:**::*:****.**********************:**::*********. *:** **:***:*** :** * **************************************************** *********** ***:*************:*********************** *****:::***.* :.* .* **.****************:****** :*** * . :** . **:: *:: : * . :*:*:******", "identical_positions": 245, "similar_positions": 59, "identity": "61.71%" }, { "cls_id": "homologset.oma.817847", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A3H1-1", "uniprot_id": "A0A8I6A3H1_RAT", "id": "A0A8I6A3H1-1", "name": "thiol oxidase", "aln": "---------MSPGFLRAV-AGQGAAAAVQLLVTLG---------FLSSLVKTQVT--------GVLDDCLCDIDSIDNFNTYKIFPKIKKLQERDYFRYYKVNLKRPCPFWAE-DGHCSIKDCHVEPCPESKIPVGIKAGRSNKYSQAANNTKELDDCEQAN--------KLGAINSTLSNESKEAFIDWARYDDSQDHFCELDDERSPAAQYVDLLLNPERYTGYKGSSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDNGESFYTWLEGLCLEKRVFYKLISGLHASINLHLCANYLLEET--WGKPS--WGPNIKEFKRRFDTVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNLEDDADTKTLLLSIFQD---TKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKE-------IQKLPENSPSKGFQLTRQEIVALLNAFGSFTLYLEPILPPRDAG---------QEASFRVLGSWPAICQQYRSTNLGSMLRTH--------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2E9-1", "uniprot_id": "ERO1B_MOUSE", "id": "Q8R2E9-1", "name": "ERO1-like protein beta", "aln": "---------MSPGFRRAV-TGQGAAAAVQLLVTLS---------FLSSLVKTQVT--------GVLDDCLCDIDSIDKFNTYKIFPKIKKLQERDYFRYYKVNLKRPCPFWAE-DGHCSIKDCHVEPCPESKIPVGIKAGRSNKYSQAANSTKELDDCEQAN--------KLGAINSTLSNESKEAFIDWARYDDSQDHFCELDDERSPAAQYVDLLLNPERYTGYKGSSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDDGESFYTWLEGLCLEKRVFYKLISGLHASINLHLCANYLLEET--WGKPS--WGPNIKEFRRRFDPVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNVEDDADTKTLLLSIFQD---TKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKE-------IQNLPENSPSKGFQLTRQEIVALLNAFGRLS------------------------TSIRELQNFKALLQHRR-------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A5G2RJY9-1", "uniprot_id": "A0A5G2RJY9_PIG", "id": "A0A5G2RJY9-1", "name": "thiol oxidase", "aln": "---------MS-GVQRAG-AGQGAAAAVQLLVTLS---------FLPRVVEAQVT--------GVLDDCLCDIDSIDNFNTFKIYPKIKKLQERDYFRYYKVNLKRPCPFWAE-DGHCSIKDCHVEPCPESKIPVGIKAGSSNKYLKVANNTKELEDCEQAS--------KLGAINSTLSNQSKEAFIDWARYDDSQDHFCELDDERSPAAQYVDLLLNPERYTGYKGSSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDNGESFYTWLEGLCLEKRVFYKLISGLHASINLHLCANYLLKET--WGKPS--WGPNMKEFKRRFDPVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNVEEDADTKTLLLNIFQD---TKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKE-------IQKLPENSPSKGFQLTRQEIVALLNAFGRLS------------------------TSIRELQNFKVLLQHSR-------------------------------------------------------------------------------------------------------------------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "F1MW08-1", "uniprot_id": "F1MW08_BOVIN", "id": "F1MW08-1", "name": "thiol oxidase", "aln": "---------MSPGVRRAG-AGQGAAAAVQLLVTLS---------FLPSVVEAQVT--------GVLDDCLCDIDSIDNFNTFKIFPKIKKLQERDYFRYYKVNLKRPCPFWAE-DGHCSIKDCHVEPCPESKIPVGIKAGNSNKYSKVANNTKELEDCEQAS--------KLGAINSTLSNQSKEAFIDWARYDDSQDHFCELDDERSPAAQYVDLLLNPERYTGYKGSSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDDGESFYTWLEGLCLEKRVFYKLISGLHASINLHLCANYLLEET--WGKPS--WGPNMKEFKRRFDPVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNVQEDADTKTLLLNIFQD---TKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKE-------IQKLPENSPSKGFQLTRQEIVALLNAFGRLS------------------------TSIRELQNFKVLLQHSRCHCI---------------------------------------------------------------------------------------------------------------", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q86YB8-1", "uniprot_id": "ERO1B_HUMAN", "id": "Q86YB8-1", "name": "ERO1-like protein beta", "aln": "---------MSQGVRRAG-AGQGVAAAVQLLVTLS---------FLRSVVEAQVT--------GVLDDCLCDIDSIDNFNTYKIFPKIKKLQERDYFRYYKVNLKRPCPFWAE-DGHCSIKDCHVEPCPESKIPVGIKAGHSNKYLKMANNTKELEDCEQAN--------KLGAINSTLSNQSKEAFIDWARYDDSRDHFCELDDERSPAAQYVDLLLNPERYTGYKGTSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDDGESFYTWLEGLCLEKRVFYKLISGLHASINLHLCANYLLEET--WGKPS--WGPNIKEFKHRFDPVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNAEEDADTKTLLLNIFQD---TKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKE-------IQKLPENSPSKGFQLTRQEIVALLNAFGRLS------------------------TSIRDLQNFKVLLQHSR-------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0Y127-1", "uniprot_id": "A0A8V0Y127_CHICK", "id": "A0A8V0Y127-1", "name": "thiol oxidase", "aln": "---------MSGGGSGSRSTAAWARWATRLLAALG---------SVL-AAEAQLT--------GVLDDCLCDIESIDDFNTFKIFPKIQKLQERDYFRYYKVNLKRPCPFWAD-DGHCSIKDCHVEPCPESKIPVGIKAGSSNKYSKAANNSKELEDCEQAN--------KLGAVNSTLSNQSKEAFIDWARYDDSQDHFCELDDERSPDAQYVDLLLNPERYTGYKGPSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGGDDGESFYTWLEGLCLEKRVFYKLISGLHASINLHLCANYLLEET--WGKPR--WGPNVKEFTRRFDPIETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSVVDLYTGNGHEDAESKALLLEIFRD---TKSFHMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKE-------IQNLPENSPSKGFQLTRQEIVALVNAFGRLS------------------------TSIKELQNFKVLLQQTR-------------------------------------------------------------------------------------------------------------------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9V3A6-1", "uniprot_id": "ERO1L_DROME", "id": "Q9V3A6-1", "name": "Ero1-like protein", "aln": "--------MTTRTVQRNLWASAAVVLVLLLLWTDTTGG------YFAAIDETETSKNCFCELEGSINDCSCDVDTVDHFNNMKIYPRLQSLLVKNFFRFYKVNLRQECPFWPD-DSRCAMRFCQVENCEEQAIPQGIKDKGEHKEKAAFKYTREAQVGGSACSDGEDFDSSLGFLDTSISDQAHREFELWAKHDEAEEDFCIVDDHEE-GSQYVDLLLNPERYTGYKGESAHRIWKSIYLENCFGGN--NETANKFSNYVPHLD-------LRNVCLEQRAFYRIISGLHSSINIHLCSKYLLSESKDFLDPQGIWGPNVKEFKRRFSPETTSGEGPHWLRNLYFIYLIELRALAKAAPYLRR--EDYYTGIAEEDDEVKLAINDMLSV---IENFQSHFDENALFSNGIASIK-FKHDYKEKFRNISRIMSCVGCDKCKLWGKLQTQGLGTALKILYSEKLNLATESGLWDKPHIEADPIFRLSRTEIVALFNAFGRLS------------------------NSIYEMENFRCVLR----------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9C7S7-1", "uniprot_id": "ERO1_ARATH", "id": "Q9C7S7-1", "name": "Endoplasmic reticulum oxidoreductin-1", "aln": "MGKGAIKEEESEKKRKTWRWPLATLVVVFLAVAVSSRTNSNVGFFFSDRNSCSCSLQKTGKYKGMIEDCCCDYETVDNLNTEVLNPLLQDLVTTPFFRYYKVKLWCDCPFWPD-DGMCRLRDCSVCECPENEFPEPFKKP------FVPGLPSDDLKCQEGK--------PQGAVDRTIDN---RAFRGWVETKN---PWTHDDDTDSGEMSYVNLQLNPERYTGYTGPSARRIWDSIYSENCPKYSS------------------------GETCPEKKVLYKLISGLHSSISMHIAADYLLDES----RNQ--WGQNIELMYDRIL------RHPDRVRNMYFTYLFVLRAVTKATAYLEQ--AEYDTGNHAEDLKTQSLIKQLLYSPKLQTACPVPFDEAKLWQG--QSGPELKQQIQKQFRNISALMDCVGCEKCRLWGKLQVQGLGTALKILFSVGN------------QDIGDQTLQLQRNEVIALVNLLNRLSESVKMVHDMSP-----------DVERLMEDQIAKVSAKPARLRRIWDLAVSFW-------------------------------------------------------------------------------------------------------", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q03103-1", "uniprot_id": "ERO1_YEAST", "id": "Q03103-1", "name": "Endoplasmic oxidoreductin-1", "aln": "-----MRLRTAIATLCLTAFTSATSNNSYIATDQTQN-------AFNDTHFCKVDRN-----DHVSPSCNVTFNELNAIN-ENIRDDLSALLKSDFFKYFRLDLYKQCSFWDANDGLCLNRACSVDVVEDWDTLPEYWQPEILGSFNNDTMKEADDSDDECK--------FLDQLCQTSKK---------PVDIEDTINYCDVNDFNGKNAVLIDLTANPERFTGYGGKQAGQIWSTIYQDNCFTIG------------------------ETGESLAKDAFYRLVSGFHASIGTHLSKEYLNTKTG-------KWEPNLDLFMARIG------NFPDRVTNMYFNYAVVAKALWKIQPYLPEFSFCDLVNKEIKN-KMDNVISQLDTK---------IFNEDLVFAN--DLSLTLKDEFRSRFKNVTKIMDCVQCDRCRLWGKIQTTGYATALKILFEIND---------ADEFTKQHIVGKLTKYELIALLQTFGRLSESIESVNMFEKMYGKRLNGSENRLSSFFQNNFFNILKEAGKSIRYTIENINSTKEGKKKTNNSQSHVFDDLKMPKAEIVPRPSNGTVNKWKKAWNTEVNNVLEAFRFIYRSYLDLPRNIWELSLMKVYKFWNKFIGVADYVSEETREPISYKLDIQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . . .* : :: :* : :. * :*:::::.* *.** *. * : * * : . . : : .. : : :* ::* ****:*** * .* ::*.:** :** . : .:*:::**:*:**. *:. .** :: * *:. : *: . * : *:** * . :*: * .*: . .. .: . . : .: *:* :: . :*.: : :*:*:: :*.** *::*:****:*. * .******:. :* : *::**.: :. :: : . ", "identical_positions": 74, "similar_positions": 113, "identity": "11.28%" }, { "cls_id": "homologset.oma.817848", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R180-1", "uniprot_id": "ERO1A_MOUSE", "id": "Q8R180-1", "name": "ERO1-like protein alpha", "aln": "---------------MGRAWGLLVG------LLGVVWLLRLGHGEER-------------------RPETAAQRCFCQVSGYLDDCTCDVETIDKFNNYRLFPRLQKLLESDYFRYYKVNLKKPCPFWNDINQCGRRDCAVKPCHSDEVPDGIKSASYKYSEEAN-RIEECEQAERLGAVDESLSEETQKAVLQWTKHDDSSDSFCEIDDIQSPDAEYVDLLLNPERYTGYKGPDAWRIWSVIYEENCFKPQTIQR---PLASGRGKSKENTFYNWLEGLCVEKRAFYRLISGLHASINVHLSARYLLQDTWLEKKWGHNVTEFQQRFDGILTEGEGPRRLRNLYFLYLIELRALSKVLPFFERPDFQLFTGNKVQDAENKALLLEILHEIKS---FPLHFDENSFFAGDKNEAHKLKEDFRLHFRNISRIMDCVGCFKCRLWGKLQTQGLGTALKILFSEKLIANMPESGPSYEFQLTRQEIVSLFNAFGRISTSVRELENFRHLLQNVH-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8R4A1-1", "uniprot_id": "ERO1A_RAT", "id": "Q8R4A1-1", "name": "ERO1-like protein alpha", "aln": "---------------MGRGWGLLVG------LLGVVWLLRSGQGEEQ-------------------QQETAAQRCFCQVSGYLDDCTCDVETIDKFNNYRLFPRLQKLLESDYFRYYKVNLRKPCPFWNDINQCGRRDCAVKPCHSDEVPDGIKSASYKYSKEAN-LLEECEQAERLGAVDESLSEETQKAVLQWTKHDDSSDSFCEVDDIQSPDAEYVDLLLNPERYTGYKGPDAWRIWSVIYEENCFKPQTIQR---PLASGQGKHKENTFYSWLEGLCVEKRAFYRLISGLHASINVHLSARYLLQDNWLEKKWGHNVTEFQQRFDGVLTEGEGPRRLKNLYFLYLIELRALSKVLPFFERPDFQLFTGNKVQDVENKELLLEILHEVKS---FPLHFDENSFFAGDKNEAHKLKEDFRLHFRNISRIMDCVGCFKCRLWGKLQTQGLGTALKILFSEKLIANMPESGPSYEFQLTRQEIVSLFNAFGRISTSVRELENFRHLLQNVH-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B6CVD7-1", "uniprot_id": "ERO1A_PIG", "id": "B6CVD7-1", "name": "ERO1-like protein alpha", "aln": "---------------MGHRWGFLIV------FLGAVGLLGSGYGRQQ-------------------PSETAAQRCFCQVSGYLDDCTCDVETIDRFNNYRLFPRLQKLLESDYFRYYKVNLKRPCPFWNDINQCGRRDCAVKPCQSDEIPDGIKSASYKYSEEANNLIEECEQAERLGAVDESLSEETQKAVLQWTKHDDSSDNFCEADDIQSPDAEYVDLLLNPERYTGYKGPDAWKIWNVIYEENCFKPQTIKRPLNPLASGQGKSEENTFYSWLEGLCVEKRAFYRLISGLHASINVHLSARYLLQDTWLEKKWGHNITEFQQRFDGILTEGEGPRRLKNLYFLYLIELRALSKVVPFFERPDFQLFTGNKVQDAENKMLLLDILHEIKS---FPLHFDENSFFAGDKKEANKLKEDFRLHFRNISRIMDCVGCLKCRLWGKLQTQGLGTALKILFSEKLIANMPESGPSYEFHLTRQEIVSLFNAFGRISTSVKELENFRNLLQNIH-----------------------------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A5PJN2-1", "uniprot_id": "ERO1A_BOVIN", "id": "A5PJN2-1", "name": "ERO1-like protein alpha", "aln": "---------------MGRRWGFLIG------FLVAVGLLGLGHGEQQ-------------------PSETAAQRCFCQVSGYLDDCTCDVETIDKFNNYRLFPRLQKLLESDYFRYYKVNLKRPCPFWNDINQCGRRDCAVKPCHSDEVPDGIKSASYKYSEEANNLIEECEQAERLGAVDESLSEETQKAVLQWTKHDDSSDNFCEVDDIQSPDAEYVDLLLNPERYTGYKGPDAWKIWNVIYEENCFKPQTIKRPLNPLASGQGKSEENTFYSWLEGLCVEKRAFYRLISGLHASINVHLSARYLLQDTWLEKKWGHNITEFQQRFDGILTEGEGPRRLKNLYFLYLIELRALSKVVPFFERPDFQLFTGNKDQDAENKMLLLEILHEIKS---FPLHFDENSFFAGNKKEANKLKEDFRLHFRNISRIMDCVGCLKCRLWGKLQTQGLGTALKILFSEKLIANMPESGPSYEFHLTRQEIVSLFNAFGRISTSVKELENFRNLLQNIH-----------------------------", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q96HE7-1", "uniprot_id": "ERO1A_HUMAN", "id": "Q96HE7-1", "name": "ERO1-like protein alpha", "aln": "---------------MGRGWGFLFG------LLGAVWLLSSGHGEEQ-------------------PPETAAQRCFCQVSGYLDDCTCDVETIDRFNNYRLFPRLQKLLESDYFRYYKVNLKRPCPFWNDISQCGRRDCAVKPCQSDEVPDGIKSASYKYSEEANNLIEECEQAERLGAVDESLSEETQKAVLQWTKHDDSSDNFCEADDIQSPEAEYVDLLLNPERYTGYKGPDAWKIWNVIYEENCFKPQTIKRPLNPLASGQGTSEENTFYSWLEGLCVEKRAFYRLISGLHASINVHLSARYLLQETWLEKKWGHNITEFQQRFDGILTEGEGPRRLKNLYFLYLIELRALSKVLPFFERPDFQLFTGNKIQDEENKMLLLEILHEIKS---FPLHFDENSFFAGDKKEAHKLKEDFRLHFRNISRIMDCVGCFKCRLWGKLQTQGLGTALKILFSEKLIANMPESGPSYEFHLTRQEIVSLFNAFGRISTSVKELENFRNLLQNIH-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0YY13-1", "uniprot_id": "A0A8V0YY13_CHICK", "id": "A0A8V0YY13-1", "name": "ERO1-like protein alpha", "aln": "----------MAIFHRSRRHQLLSQSRPCAALCQPAPALPSHSGPARSVGRGLSPRLSHRQPPVPLRAATVKQQALLSVTGHLDDCTCDVETIDAFNNYKLFPRLNQLLESDYFRYYKVNLKKPCPFWNDNSHCGIRDCAVKPCPSDEVPDGIRSAGYKYSEEANSRAEECEEANRLGAVDESLSKETQQAVLQWTWHDDSSDSFCEADDIHSPDAEYVDLLLNPERYTGYKGPDAWKIWNSIYEENCFKPQNVKR---PLTSGRGDDGGQMFYKWLKGVCVEKRAFYRLISGLHASINIHLSARYLLQDTWSEKKWGPNVTEFQQRFDEVVTRGEGPRRLKNLYFLYLIELRALSKVLPFFERPGFQLYTGNQSHDAEIKNLLLEVLHLAKS---FPLHFDENSFFAGNKKEAAKLKEEVRLHFKNISKIMDCVGCFKCRLWGKLQTQGLGTALKILFSESLIEKIPESGPSYGFQLTRQEIVALFNAFGRISTSVRELENFRAILRTMR-----------------------------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q7X9I4-1", "uniprot_id": "ERO2_ARATH", "id": "Q7X9I4-1", "name": "Endoplasmic reticulum oxidoreductin-2", "aln": "MAETDVGSVKGKEKGSGKRWILLIGAIAAVLLAVVVAVFLNTQNSSISEFTG--------------KICNCRQAEQQKYIGIVEDCCCDYETVNRLNTEVLNPLLQDLVKTPFYRYFKVKLWCDCPFWPDDGMCRLRDCSVCECPESEFPEVFKKPLSQYN-------PVCQEGKPQATVDRTLDTR---AFRGWTVTDN---PWTSDDETDNDEMTYVNLRLNPERYTGYIGPSARRIWEAIYSENCPKHT------------------------SEGSCQEEKILYKLVSGLHSSISVHIASDYLLDEATN--LWGQNLTLLYDRVL------RYPDRVQNLYFTFLFVLRAVTKAEDYLG--EAEYETGNVIEDLKTKSLVKQVVSDPKTKAACPVPFDEAKLWKGQR--GPELKQQLEKQFRNISAIMDCVGCEKCRLWGKLQILGLGTALKILFTVNGEDNLRHN-----LELQRNEVIALMNLLHRLSESVKYVHDMSPAAERIAGGHASSGNSFWQRIVTSIAQSKAVSGKRS", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :* : . : . . * . * ::** ** **:: :*. * * *:.*::: ::**:**:* **** * . * ***:* * ..*.*: ::.. :*. *::.: .:**.:*. . *. ** *: : . *: .. : **:* ********* **.* :**. **.*** * :* * *:: :*:*:****:**.:*::: ***:: ** *:* : :*. . * *::**** :*: ***::*. :: : *** .* : * *: ::: *: *: *** .:: *:: . :**::.. :*:*** ******* ********* **********: . :: .. :.* *:*:::*:* : *:* **: :.:: . : ", "identical_positions": 149, "similar_positions": 131, "identity": "27.59%" }, { "cls_id": "homologset.oma.817873", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CWP8-1", "uniprot_id": "DPOD4_MOUSE", "id": "Q9CWP8-1", "name": "DNA polymerase delta subunit 4", "aln": "---------MGRKR-FITDSYPVVKKREGPPGHSKGELAPELGEDTQSL--SQEETELELLRQFDLAWQYGPCTGITRLQRWSRAEQMGLKPPLEVYQVLKAHPEDPHFQCSLWHLYPL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P6U6-1", "uniprot_id": "Q6P6U6_RAT", "id": "Q6P6U6-1", "name": "", "aln": "---------MGRKR-FITDSYPVVKKREGPPGHNKGELAPELGEDTQSL--SQEETELELLRQFDLAWQYGPCTGITRLQRWHRAEQMGLKPPVEVYQVLKTHPEDSRFQCSLWHLYPL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A9J7FRJ0-1", "uniprot_id": "A0A9J7FRJ0_CRIGR", "id": "A0A9J7FRJ0-1", "name": "", "aln": "---------MGRKR-FITDSYPVVKKREGPPGHSKRELAPELGEDTQSL--SQEEAQLELLRQFDLAWQYGPCTGITRMQRWHRAEQMGLKPPLEVHQVLKTHSEDPRFQFSHQELLDRIHGQ", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q9HCU8-1", "uniprot_id": "DPOD4_HUMAN", "id": "Q9HCU8-1", "name": "DNA polymerase delta subunit 4", "aln": "---------MGRKR-LITDSYPVVKRREGPAGHSKGELAPELGEEPQPR--DEEEAELELLRQFDLAWQYGPCTGITRLQRWCRAKQMGLEPPPEVWQVLKTHPGDPRFQCSLWHLYPL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RUX5-1", "uniprot_id": "F1RUX5_PIG", "id": "F1RUX5-1", "name": "", "aln": "---------MGRKR-LITDSYPVVKRREGPAGHSKGELALKLEEEPEPPPPSVDEAELELLRQFDLAWQYGPCTGITRLQRWHRAEQMGLAPPPEVRQVLQTHPGDPRFQCSLWHFYPL----", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "F1R563-1", "uniprot_id": "F1R563_DANRE", "id": "F1R563-1", "name": "", "aln": "MTISYQRPDMTPKRGLITDTFKVVKKARRGGKRSKSPSPPKAEPEPPQL--SEREKDIQELKNFDLDWKFGPCTGISRLQRWERAALHGLNPPQEIKDILLKEDTDPEYTQSLWRDYPF----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ** :***:: ***: . :.* . : :. . * ::: *::*** *::******:*:*** ** ** ** *: ::* . *..: * . ", "identical_positions": 36, "similar_positions": 29, "identity": "29.27%" }, { "cls_id": "homologset.oma.817891", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "G8JKV7-1", "uniprot_id": "G8JKV7_BOVIN", "id": "G8JKV7-1", "name": "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "aln": "MR---LLLLLAPLGWLLLAETKGDAKP--EDNLLVLTVATKETEGFRRFKRSAQFFNYKIQALGLGEDWPGEA--MLAGGGLKVRLLKKALEKHADKENLVILFTDSYDVVFASGPRELLKKFRQARSQVVFSAEELIYPDRRLEAKYPVVS-DGKRFLGSGGFIGYAPNLSKLVAEWEGQDSDSDQLFYTKIFLDPEKREQINITLDHRCRIFQNLDGALDEVVLKFEM--GQVRARNLAYDTLPVLIHGNGPTKLQLNYLGNYIPRFWTFETGCAVCDEGLRSLKGIGDEALPAVLVGVFIEQPTPFLSLFFQRLLRLHYPQKRLRLFIHNHEQHHKAQVEQFLAEHGDEYQSVKLVGPEVRVANADARNMGADLCRQDRGCTYYFSVDADVALTEPKTLRLLIEQNKNVITPLMTRHGRLWSNFWGALSADGYYARSEDYVDIVQGRRVGVWNVPYISNIYLIKGSALRAELQETDLFHHSKLDPDMAFCANIRQQDVFMFLTNRHSFGHLLSLDSYQTTHLHNDLWEVFSNPEDWKEKYIHENYTKALAG-KMVEMPCPDVYWFPIFTETACDELVEEMEHYGQWSLGDNKDNRIQGGYENVPTIDIHMNQINFEREWHKFLVEYIAPMTEKLYPGYYTRAQFDLA-FVVRYKPDEQPSLVPHHDASTFTINIALNRVGVDYEGGGCRFLRYNCSIRAPRKGWTLMHPGRLTHYHEGLPTTKGTRYIAVSFVDP", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A480M584-1", "uniprot_id": "A0A480M584_PIG", "id": "A0A480M584-1", "name": "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "aln": "MR---LLLLLAPLGWLLLTETKGDAKP--EDNLLVLTVATKETEGFRRFKRSAQFFNYKIQALGLGEDWNEKE--ASSGGGLKVRLLKKALEKHAD-ENLVILFTDSYDVVFASGPRELLKKFRQAKSQVVFSAEELIYPDRRLEAKYPAVS-DGKRFLGSGGFIGYAPNLSKLVAEWEGQDSDSDQLFYTKIFLDPEKRERINITLDHRCRIFQNLDGALDEVVLKFEM--GQVRARNLAYDTLPVLIHGNGPTKLQLNYLGNYIPRFWTFETGCSVCDEGLRSLKGIGDEALPTVLVGLFIEQPTPFLSLFFQRLLRLQYPRKRMRLFIHNHEQHHKALVEQFLAEHGDEYQSVKLVGPEVRVANADARNMGADLCRQDRSCTYYFSVDADVALTEPKTLRLLIEQNKNVLAPLMTRHGRLWSNFWGALSADGYYARSEDYVDIVQGRRVGVWNVPYISNVYLIKGSALRAELQQTDLFHHSKLDPDMAFCANIRQQDVFMFLTNRHAFGHLLSLDSYQTTHLHNDLWEVFSNPEDWKEKYIHENYTKALAG-KLVETPCPDVYWFPIFTETACDELVEEMEHYGQWSLGDNKDNRIQGGYENVPTIDIHMNQISFEREWHKFLVEYIAPMTEKLYPGYYTRAQFDLA-FVVRYKPDEQPSLMPHHDASTFTINIALNRVGVDYEGGGCRFLRYNCSIRAPRKGWTLMHPGRLTHYHEGLPTTKGTRYIAVSFVDP", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q02809-1", "uniprot_id": "PLOD1_HUMAN", "id": "Q02809-1", "name": "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "aln": "MR---PLLLLALLGWLLLAEAKGDAKP--EDNLLVLTVATKETEGFRRFKRSAQFFNYKIQALGLGEDWNVEKG-TSAGGGQKVRLLKKALEKHADKEDLVILFADSYDVLFASGPRELLKKFRQARSQVVFSAEELIYPDRRLETKYPVVS-DGKRFLGSGGFIGYAPNLSKLVAEWEGQDSDSDQLFYTKIFLDPEKREQINITLDHRCRIFQNLDGALDEVVLKFEM--GHVRARNLAYDTLPVLIHGNGPTKLQLNYLGNYIPRFWTFETGCTVCDEGLRSLKGIGDEALPTVLVGVFIEQPTPFVSLFFQRLLRLHYPQKHMRLFIHNHEQHHKAQVEEFLAQHGSEYQSVKLVGPEVRMANADARNMGADLCRQDRSCTYYFSVDADVALTEPNSLRLLIQQNKNVIAPLMTRHGRLWSNFWGALSADGYYARSEDYVDIVQGRRVGVWNVPYISNIYLIKGSALRGELQSSDLFHHSKLDPDMAFCANIRQQDVFMFLTNRHTLGHLLSLDSYRTTHLHNDLWEVFSNPEDWKEKYIHQNYTKALAG-KLVETPCPDVYWFPIFTEVACDELVEEMEHFGQWSLGNNKDNRIQGGYENVPTIDIHMNQIGFEREWHKFLLEYIAPMTEKLYPGYYTRAQFDLA-FVVRYKPDEQPSLMPHHDASTFTINIALNRVGVDYEGGGCRFLRYNCSIRAPRKGWTLMHPGRLTHYHEGLPTTRGTRYIAVSFVDP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63321-1", "uniprot_id": "PLOD1_RAT", "id": "Q63321-1", "name": "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "aln": "MR---SLLLLASLAWLLLAQAKDDAKL--EDNLLVLTVATKETEGFRRFKRSAQFFNYKIQSLGLGEDWSAAGGPSAAGGGQKVRLLKKALKKYADKEDLVILFVDSYDVVFASGPRELLKKFQQAKSRVVFSAEELIYPDRRLEAKYPTVP-DGKRFLGSGGFIGYAPSLSKLVAEWEGQDNDSDQLFYTKIFLDPEKREQINISLDHRCRIFQNLDGALDEVVLKFEM--GHVRARNLAYDTLPVVIHGNGPTKLQVNYLGNYIPRFWTFETGCTVCDEGLRSLKGIGDEALPTVLVGVFIEQPTPFLSLFFRRLLHLRYPQKQMRLFIHNQEQHHKLQVEQFLAEHGGEYQSVKLVGPEVRMANADARNMGADLCRQDQTCTYYFSVDADVALTEPNSLRLLIEQNKNVIAPLMTRHGRLWSNFWGALSADGYYARSEDYVDIVQGRRVGVWNVPYISNIYLIKGSALRAELRHVDLFHYSKLDPDMSFCANVRQQEVFMFLTNRHTFGHLLSLDNYQTTHLHNDLWEVFSNPQDWKEKYIHENYTKALAG-KLVETPCPDVYWFPIFTEVACDELVEEMEHYGQWSLGDNKDNRIQGGYENVPTIDIHMNQITFEREWHKFLVEYIAPLTEKLYPGYYTKAQFDLA-FVVRYKPDEQPSLMPHHDASTFTINIALNRVGEDYEGGGCRFLRYNCSVRAPRKGWALMHPGRLTHYHEGLPTTKGTRYIAVSFVDP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0E2-1", "uniprot_id": "PLOD1_MOUSE", "id": "Q9R0E2-1", "name": "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "aln": "MR---SLLLLAPLAWLLLVQAKDDAKL--EDNLLVLTVATKETEGFRRFKRSAQFFNYKIQSLGLGEDWSVDGGPAAAGGGQKVRLLKKALEKHADKEDLVILFVDSYDVVFASGPRELLKKFQQAKSQVVFSAEEHIYPDRRLEAKYPTVP-DGKRFLGSGGFIGYAPSLSKLVAEWEGQDSDSDQLFYTKIFLNPEKREQINISLDHRCRIFQNLDGALDEVVLKFEM--GHVRARNLAYDTLPVVVHGNGPTKLQLNYLGNYIPRFWTFETGCTVCDEGLRSLKGIGDEALPTVLVGVFIEQPTPFLSLFFLRLLRLRYPQKQMRLFIHNQERHHKLQVEQFLAEHGSEYQSVKLVGPEVRMANADARNMGADLCRQDQTCTYYFSVDADVALTEPNSLRLLIEQNKNVIAPLMTRHGRLWSNFWGGLSADGYYARSEDYVDIVQGRRVGVWNVPYISNIYLIKGSALRAELQNVDLFHYSKLDSDMSFCANVRQQEVFMFLTNRHTFGHLLSLDNYQTTHLHNDLWEVFSNPEDWKEKYIHENYTKALAG-KLVETPCPDVYWFPIFTEAACDELVEEMEHYGQWSLGDNKDNRIQGGYENVPTIDIHMNQITFEREWHKFLVEYIAPMTEKLYPGYYTRAQFDLA-FVVRYKPDEQPSLMPHHDASTFTVNIALNRVGEDYEGGGCRFLRYNCSVRAPRKGWALLHPGRLTHYHEGLPTTKGTRYIAVSFVDP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8WIN7-1", "uniprot_id": "A8WIN7_DANRE", "id": "A8WIN7-1", "name": "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "aln": "MRGVLAFLACLFASFPPLHCNQQGSIP--EGDLLVLTVATQETDGFRRFLRSAKHFNYTIKVLGRGETWRGGDYMTAPGGGQKVRLLKSALEDIQE-EKKVILFVDSYDVIFSSGPKELLKKFQQAKHKVVFSAETLIWPDRHLEDKHPHVR-EGKRFLGAGGFIGYAANLKKMLSDWSGADGDSDQLFYTKIYINKEKRKSINITLDSKCRLFQNLHGALDEVVLKFED--GRVRARNVLYDTLPVIIHGNGPTKLQINYLGNYIPNLWTFETGCTMCNQDRRLLSGLQESEYPVVVIGIFIQQPTPFVTVFFERLFNLKYPKNRLKLFIYNQETHHEQHIHAFLDSHESEYQGVKLIGPEEDIDPVSSRNLGFDMCREDIDCEYFFSIDVDVVLKNEDTLRILIEHNKPFIAPMLTKPGRLWTNFWGALSADGFYARSEDYVDIVQGHRVGLWNVPYVSHIFLIKADTLRTDLKDPDLFKSTTLDPDMAFCEKIRNKGVFMFVTNMDTFGRVLSTDNYQTNHLHNDLWQIFENPVEWEERYIHPNYSRVLKD-EFIETPCPDVYWFPIFSEVACDHLVEEMENFGQWSGGANVDNRIQGGYENVPTIDIHMNQVGYEKEWQKFLLDYIAPVTEKMFPGYYTRAQFDLA-FVVRYKPDEQPSLRPHHDASTFTINIALNHVGIDFQGGGCRFLRYDCSIRSPRKGWAFMHPGRLTHYHEGLPTTEGVRYIAVSFVDP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTH0-1", "uniprot_id": "PLOD_DROME", "id": "Q9VTH0-1", "name": "Procollagen-lysine,2-oxoglutarate 5-dioxygenase", "aln": "MR----IQQSALLLLLLAVTSQGDAESNWNDKIKVFTVATEPTDGYTRYIRSARVYDIEVTTLGLGEEWKGGD-MQKPGGGFKLNLLREAIAPYKNEPETIILFTDSYDVIITTTLDEIFEKFKESGAKILFSAEKYCWPDKSLANDYPEVEGKASRFLNSGAFIGYAPQVFALLVDP-IEDTADDQLYFTKIFLDETKRAKLGLKLDVQSRLFQNLHGAKNDVKLKVDLESNQGVLQNVDFMTTPSIIHGNGLSKVDLNAYGNYLAR--TFNGVCLLCQEN---LLDLEETNLPVISLALMVTQPVPFFDQFLEGIESLNYPKEKLHLLIYSNVAFHDDDIKSFVNKHAKEYATAKFALSTDELDERQGRQLALDKARLHQS-DYIFFVDADAHIDDGEVLRELLRLNKQFVAPIFSKHKELWSNFWGALSEGGYYARSHDYVDIVKRELIGMFNVPHVTSIYLVKKTAFDAIS-----FKHKEFDPDMAMCESLRNAGIFMYASNLRIFGHLVNADDFNTTVTRPDFYTLFSNEIDWTEKYIHPNYSLQLNESNKIQQPCPDVYWFQIVSDAFCDDLVAIMEAHNGWSDGSNNDNRLEGGYEAVPTRDIHMKQVGLERLYLKFLQMFVRPLQERAFTGYFHNPPRALMNFMVRYRPDEQPSLRPHHDSSTYTINIAMNRAGIDYQGGGCRFIRYNCSVTDTKKGWMLMHPGRLTHYHEGLLVTNGTRYIMISFIDP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 271, "similar_positions": 244, "identity": "36.72%" }, { "cls_id": "homologset.oma.817892", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q811A3-1", "uniprot_id": "PLOD2_RAT", "id": "Q811A3-1", "name": "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "aln": "MGDRGVRLGLLMPMLALLSWAASLGVAEETPSRIPADKLLVITVATKENDGFHRFMNSAKYFNYTVKVLGQGQEWRGGDGMNSIGGGQKVRLMKEAMEHYAGQDDLVILFTECFDVIFAGGPEELLKKFQKTNHKIVFAADALLWPDKRLADKYPGVHIGKRYLNSGGFIGYAPYISRLVQQWNLQDNDDDQLFYTKVYIDPLKREALNITLDHRCKIFQALNGATDEVVLKFENGKSRVKNTFYETLPVAINGNGPSKILLNYFGNYVPNSWTQENGCALCDFDASDLSTVDVYPKVTLGVFIEQPTPFQPRFLDLLLTLDYPKEALRLFVHNKEVYHEKDIKAFVDKAKHDISSIKIVGPEENLSQAEARNMGMDFCRQDEKCDYYFSVDADVVLTNPRTLKILIEQNRKIIAPLVTRHGKLWSNFWGALSPDGYYARSEDYVDIVQGNRVGIWNVPYMANVYLIQGKTLRSEMSERNYFVRDKLDPDMSLCRNARDMGVFMYISNRHEFGRLISTANYNTSHLNNDLWQIFENPVDWKEKYINRDYSKIFTENIVEQPCPDVFWFPIFSERACDELVEEMEHYGKWSGGKHHDSRISGGYENVPTDDIHMKQIDLENVWLHFIREFIAPVTLKVFAGYYTKGFALLNFVVKYSPERQRSLRPHHDASTFTINIALNNVGEDFQGGGCKFLRYNCSIESPRKGWSFMHPGRLTHLHEGLPVKNGTRYIAVSFIDP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0B9-1", "uniprot_id": "PLOD2_MOUSE", "id": "Q9R0B9-1", "name": "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "aln": "MGDRGARPGRLMPMLALLSWAAGLGVAEETPGRIPADKLLVITVATKENDGFHRFMNSAKYFNYTVKVLGQGQEWRGGDGMNSIGGGQKVRLLKEAMEHYASQEDLVILFTECFDVVFAGGPEEVLKKFQKTNHKIVFAADGLLWPDKRLADKYPVVHIGKRYLNSGGFIGYAPYISRLVQQWNLQDNDDDQLFYTKVYIDPLKREAFNITLDHKCKIFQALNGATDEVVLKFENGKSRVKNTFYETLPVAINGNGPTKILLNYFGNYVPNSWTQENGCALCDVDTIDLSTVDVPPKVTLGVFIEQPTPFLPRFLNLLLTLDYPKEALQLFIHNKEVYHEKDIKVFVDKAKHDISSIKIVGPEENLSQAEARNMGMDFCRQDEKCDYYFSVDADVVLTNPRTLKFLIEQNRKIIAPLVTRHGKLWSNFWGALSPDGYYARSEDYVDIVQGNRVGIWNVPYMANVYLIQGKTLRSEMNERNYFVRDKLDPDMALCRNARDMGVFMYISNRHEFGRLISTANYNTSHLNNDFWQIFENPVDWKEKYINRDYSKIFTENIVEQPCPDVFWFPIFSERACDELVEEMEHYGKWSGGKHHDSRISGGYENVPTDDIHMKQIGLENVWLHFIREFIAPVTLKVFAGYYTKGFALLNFVVKYSPERQRSLRPHHDASTFTINIALNNVGEDFQGGGCKFLRYNCSIESPRKGWSFMHPGRLTHLHEGLPVKNGTRYIAVSFIDP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00469-1", "uniprot_id": "PLOD2_HUMAN", "id": "O00469-1", "name": "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "aln": "MGGCTVKPQLLLLALVLHPWNPCLGADSEKPSSIPTDKLLVITVATKESDGFHRFMQSAKYFNYTVKVLGQGEEWRGGDGINSIGGGQKVRLMKEVMEHYADQDDLVVMFTECFDVIFAGGPEEVLKKFQKANHKVVFAADGILWPDKRLADKYPVVHIGKRYLNSGGFIGYAPYVNRIVQQWNLQDNDDDQLFYTKVYIDPLKREAINITLDHKCKIFQTLNGAVDEVVLKFENGKARAKNTFYETLPVAINGNGPTKILLNYFGNYVPNSWTQDNGCTLCEFDTVDLSAVDVHPNVSIGVFIEQPTPFLPRFLDILLTLDYPKEALKLFIHNKEVYHEKDIKVFFDKAKHEIKTIKIVGPEENLSQAEARNMGMDFCRQDEKCDYYFSVDADVVLTNPRTLKILIEQNRKIIAPLVTRHGKLWSNFWGALSPDGYYARSEDYVDIVQGNRVGVWNVPYMANVYLIKGKTLRSEMNERNYFVRDKLDPDMALCRNAREMGVFMYISNRHEFGRLLSTANYNTSHYNNDLWQIFENPVDWKEKYINRDYSKIFTENIVEQPCPDVFWFPIFSEKACDELVEEMEHYGKWSGGKHHDSRISGGYENVPTDDIHMKQVDLENVWLHFIREFIAPVTLKVFAGYYTKGFALLNFVVKYSPERQRSLRPHHDASTFTINIALNNVGEDFQGGGCKFLRYNCSIESPRKGWSFMHPGRLTHLHEGLPVKNGTRYIAVSFIDP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. .: *: *.* .* . **. .*.*. **:************.*******:***************:*******:***********:**.*****.*:***::*******:*******:******:***:*****.:************ *******************:.*:****************************:******:*****:****.***********:*.*****************:*****************:***:**:.*: ***:*** *:*::********** ****::***********:**:************.*.*****:*.:************************************************:*************************************************:************:********.**************:******:****************:********* ***:*******************************************:*****************************************:.************************************************************************************************************************", "identical_positions": 653, "similar_positions": 67, "identity": "88.6%" }, { "cls_id": "homologset.oma.817893", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1MET0-1", "uniprot_id": "F1MET0_BOVIN", "id": "F1MET0-1", "name": "procollagen-lysine 5-dioxygenase", "aln": "MRACVQLGPLSAMASGPELRPLLLLLLLLSPSP-AASASDRPRGSDPVNPEKMLVITVATAETEGYRRFLQSAEFFNYTVRTLGLGEEWRGGDVARTVGGGQKVRWLKKEMEKYAEREDMVIMFVDSYDVVLAGSPSELLKKFVQSGSRLLFSAESFCWPEWGLAEQYPEVGTGKRFLNSGGFIGFAPTIHQIVRQWKYKDDDDDQLFYTRLYLDPGLREKLGLSLDHKSRIFQNLNGALDEVVLKFGRNRVRIRNVAYDTLPVVVHGNGPTKLQLNYLGNYVPNGWTPEGGCGFCNQGRRPLPGGQPPPRVLLAVFVEQPTPFLPRFLQRLLLLDYPPDRVTLFLHNNEVYHEPHIDESWPQLQDHFSAVKLVGPEEALTPGEARDMAMDICRQDPKCEFYFSLDADTVITNPQTLRILIEANRKVIAPMLSRHGKLWSNFWGALSPDEYYARSEDYVELVQRKRVGVWNVPYISQAYVIRGETLRTELPQREVFSGSDTDPDMAFCKSLRDKGIFLHLSNQHEFGRLLATSRYDTDHLHPDLWQIFDNPLDWKEQYIHENYTRALEGEGLVEQPCPDVYWFPLLSEQMCDELVEEMEHYGQWSGGRHEDSRLAGGYENVPTVDIHMKQVGYEDQWLQLLRTYVGPMTESLFPGYHTKTRAVMNFVVRYRPDEQPSLRPHHDSSTFTLNVALNHKGLDYEGGGCRFLRYDCVISSPRKGWGLLHPGRLTHYHEGLPTTRGTRYIMVSFVDP", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A8D1P4F3-1", "uniprot_id": "A0A8D1P4F3_PIG", "id": "A0A8D1P4F3-1", "name": "procollagen-lysine 5-dioxygenase", "aln": "------------MASGPGLRLLLLPLLVLSPPP-AASASDRPRGSDPVNPDKLLVITVATAETEGYRRFLRSAEFFNYTVRTLGLGEEWRGGDVARTVGGGQKVRWLKKEMEKYADREDMVIMFVDSYDVLLAGSPSELLKKFVQSGSRLLFSAEGFCWPEWGLAEQYPEVGTGKRFLNSGGFIGFAPVIHQIVRQWKYKDDDDDQLFYTRLYLDPGLREKLGLNLDHKSRIFQNLNGALDEVVLKFGRNRVRIRNVAYDTLPVVVHGNGPTKLQLNYLGNYVPNGWTPEGGCGFCDLDRRTLPGGQPPPRVLLAVFVEQPTPFLPRFLQRLLLLDYPPDRVTLFLHNNEVYHEPHIAASWPQLQDHFSAVKLVGPEEALTPGEARDMAMDTCRRDPKCEFYFSLDADAVITNPQVLRILIEENRKVIAPMLSRHGKLWSNFWGALSPDEYYARSEDYVELVQRKRVGVWNVPYISQAYVIRGETLRTELPQREVFSGSDTDPDMAFCKSVRDKGIFLHLSNRHEFGRLLATSRYDTDHLHPDLWQIFDNPLDWKEQYIHENYSRALEGEGLVEQPCPDVYWFPLLSEQMCDELVEEMEHYGQWSGGRHEDSRLAGGYENVPTVDIHMKQVGYEDQWLQLLRTYVGPMTESLFPGYHTKTRAVMNFVVRYRPDEQPSLRPHHDSSTFTLNVALNHKGLDYEGGGCRFLRYDCVISSPRKGWGLLHPGRLTHYHEGLPTTRGTRYIMVSFVDP", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "O60568-1", "uniprot_id": "PLOD3_HUMAN", "id": "O60568-1", "name": "Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3", "aln": "-----------MTSSGPGPRFLLLLPLLLPP---AASASDRPRGRDPVNPEKLLVITVATAETEGYLRFLRSAEFFNYTVRTLGLGEEWRGGDVARTVGGGQKVRWLKKEMEKYADREDMIIMFVDSYDVILAGSPTELLKKFVQSGSRLLFSAESFCWPEWGLAEQYPEVGTGKRFLNSGGFIGFATTIHQIVRQWKYKDDDDDQLFYTRLYLDPGLREKLSLNLDHKSRIFQNLNGALDEVVLKFDRNRVRIRNVAYDTLPIVVHGNGPTKLQLNYLGNYVPNGWTPEGGCGFCNQDRRTLPGGQPPPRVFLAVFVEQPTPFLPRFLQRLLLLDYPPDRVTLFLHNNEVFHEPHIADSWPQLQDHFSAVKLVGPEEALSPGEARDMAMDLCRQDPECEFYFSLDADAVLTNLQTLRILIEENRKVIAPMLSRHGKLWSNFWGALSPDEYYARSEDYVELVQRKRVGVWNVPYISQAYVIRGDTLRMELPQRDVFSGSDTDPDMAFCKSFRDKGIFLHLSNQHEFGRLLATSRYDTEHLHPDLWQIFDNPVDWKEQYIHENYSRALEGEGIVEQPCPDVYWFPLLSEQMCDELVAEMEHYGQWSGGRHEDSRLAGGYENVPTVDIHMKQVGYEDQWLQLLRTYVGPMTESLFPGYHTKARAVMNFVVRYRPDEQPSLRPHHDSSTFTLNVALNHKGLDYEGGGCRFLRYDCVISSPRKGWALLHPGRLTHYHEGLPTTWGTRYIMVSFVDP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5U367-1", "uniprot_id": "PLOD3_RAT", "id": "Q5U367-1", "name": "Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3", "aln": "-----------MAASVPEPRLLLLLLLLLPPLPPVTSASDRPRGANPVNPDKLLVITVATAETEGYRRFLQSAEFFNYTVRTLGLGQEWRGGDVARTVGGGQKVRWLKKEMEKYASQEDMIIMFVDSYDVILASSPTELLKKFVQSGSHLLFSAESFCWPDWGLAEQYPEVGVGKRFLNSGGFIGFAPTIHRIVRQWKYKDDDDDQLFYTQLYLDPGLREKLKLSLDHKSRIFQNLNGALDEVVLKFDQNRVRIRNVAYDTLPVVVHGNGPTKLQLNYLGNYVPNGWTPQGGCGFCNLNRRTLPGGQPPPRVLLAVFVEQPTPFLPRFLQRLLLLDYPPDRISLFLHNNEVYHEPHIADAWPQLQDHFSAVKLVGPEEALSSGEARDMAMDSCRQNPECEFYFSLDADAVLTNPETLRILIEQNRKVIAPMLSRHGKLWSNFWGALSPDEYYARSEDYVELVQRKRVGLWNVPYISQAYVIRGETLRTELPEKEVFSSSDTDPDMAFCRSVRDKGIFLHLSNQHEFGRLLSTSHYDTDHLHPDLWQIFDNPVDWREQYIHENYSRALDGEGLVEQPCPDVYWFPLLTEQMCDELVEEMEHYGQWSGGRHEDSRLAGGYENVPTVDIHMKQVGYEDQWLQLLRTYVGPMTEHLFPGYHTKTRAVMNFVVRYRPDEQPSLRPHHDSSTFTLNVALNHKGVDYEGGGCRFLRYDCRVSSPRKGWALLHPGRLTHYHEGLPTTRGTRYIMVSFVDP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0E1-1", "uniprot_id": "PLOD3_MOUSE", "id": "Q9R0E1-1", "name": "Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3", "aln": "-----------MAAAGPEPRLLLLLLLLLPPLPPVTSASDRPRGANAVNPDKLLVITVATAETEGYRRFLQSAEFFNYTVRTLGLGQEWRGGDVARTVGGGQKVRWLKKEMEKYADQKDMIIMFVDSYDVILASSPTELLKKFVQSGSHLLFSAESFCWPEWGLAEQYPEVGMGKRFLNSGGFIGFAPTIHQIVRQWNYKDDDDDQLFYTQLYLDPGLREKLKLSLDHKSRIFQNLNGALDEVILKFDQNRVRIRNVAYDTLPVVVHGNGPTKLQLNYLGNYVPNGWTPQGGCGFCNQTLRTLPGGQPPPRVLLAVFVEQPTPFLPRFLQRLLLLDYPPDRISLFLHNSEVYHEPHIADAWPQLQDHFSAVKLVGPEEALSAGEARDMAMDSCRQNPECEFYFSLDADAVLTNPETLRVLIEQNRKVIAPMLSRHGKLWSNFWGALSPNEYYARSEDYVELVQRKRVGVWNVPYISQAYVIRGETLRTELPQKEVFSSSDTDPDMAFCKSVRDKGIFLHLSNQHEFGRLLATSRYDTDHLHPDLWQIFDNPVDWREQYIHENYSRALDGEGLVEQPCPDVYWFPLLTEQMCDELVEEMEHYGQWSGGRHEDSRLAGGYENVPTVDIHMKQVGYEDQWLQLLRTYVGPMTEYLFPGYHTKTRAVMNFVVRYRPDEQPSLRPHHDSSTFTLNVALNHKGVDYEGGGCRFLRYDCRISSPRKGWALLHPGRLTHYHEGLPTTRGTRYIMVSFVDP", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * * *** *:*.* .:******** :.***:*:************* ***:***************:****************************.::**:*********:**.**:***********:******.****:*********** **************..**:*****:************:*********** *.******************:***.:**************:*************************:******: *.**********:****************************::*****.**:***** :********************:.********* **::*:**********:*:** :.**:*** *************************:*******************:**************:*** ***:::***.**********:*.***********:*******:**:***:*************:**:********:***:***:**************:******** ****************************************************** ********:*************************************:************** :*******.***************** ************", "identical_positions": 639, "similar_positions": 74, "identity": "84.97%" }, { "cls_id": "homologset.oma.817921", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P40897-1", "uniprot_id": "OPT1_YEAST", "id": "P40897-1", "name": "Oligopeptide transporter 1", "aln": "MSTIYRESDSLESEPSPTPTTIPIQINMEEEKKDAFVKNIDEDVNNLTATTDEEDRDPESQKFDRHSIQEEGLVWKGDPTYLPNSPYPEVRSAVSIEDDPTIRLNHWRTWFLTTVFVVVFAGVNQFFSLRYPSLEINFLVAQVVCYPIGRILALLPDWKCSKVP-----FFDLNPGPFTKKEHAVVTIAV----ALTSSTAYAMYILNAQGSFYNMKLNVGYQFLLVWTSQMIGYGAAGLTRRWVVNPASSIWPQTLISVSLFDSLHSRKVEKTVANGWTMPRYRFFLIVLIGSFIWYWVPGFLFTGLSYFNVILWGSKTRHNFIANTIFGTQSGLGALPITFDYTQVSQAMSGSVFATPFYVSANTYASVLIFFVIVLPCLYFTNTWYAKYMPVISGSTYDNTQNKYNVTKILNEDYSINLEKYKEYSPVFVPFSYLLSYALNFAAVIAVFVHCILYHGKDIVAKFKDRKNGGTDIHMRIYSKNYKDCPDWWY--LLLQIVMIGLGFVAVCCFDTKFPAWAFVIAILISLVNFIPQGILEAMTNQHVGLNIITELICGYMLPLRPMANLLFKLYGFIVMRQGLNLSRDLKLAMYMKVSPRLIFAVQIYATIISGMVNVGVQEWMMHNIDGLCTTDQP---NGFTCANGRTVFNASIIWSLP--KYLFSSGRIYNPLMWFFLIGLLFPLAVYAVQWKFPKFKFAKHIHTPVFFTGPGNIPPSTPYNYSLFFAMSFCLNLIRKRWR-AWFNKYNFVMGAGVEAGVAISVVIIFLCVQYPGGKLSWWGNNVWKRTYDNDYKKFYTLKKGETFGYDKWW", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9FME8-1", "uniprot_id": "OPT4_ARATH", "id": "Q9FME8-1", "name": "Oligopeptide transporter 4", "aln": "-----------------------------------------------MATADEFSDED-------------------------TSPIEEVRLTVTNTDDPTLPVWTFRMWFLGLISCSLLSFLNQFFSYRTEPLVITQITVQVATLPIGHFLAKVLPKTRFGLPGCGSARFSLNPGPFNMKEHVLISIFANAGSAFGSGSAYAVGIITIIKAFYGRSISFIAGWLLIITTQVLGYGWAGLLRKYVVEPAHMWWPSTLVQVSLFRALHEKDDQR-------MTRAKFFVIALVCSFGWYIVPGYLFTTLTSISWVCWAFPR--SVTAQQIGSGMRGLGLGAFTLDWTAVASFLFSPLISPFFAIANVFIGYVLLIYFVLPLAYWGFDSYNATRFPIFSSHLFTSVGNTYDIPAIVNDNFELDLAKYEQQGRINLSMFFALTYGLGFATIASTLTHVALFYGKEISERFRVSYKGKEDIHTRLMKR-YKDIPSWWFYSMLAATLLISLALCVFLNDEVQMPWWGLVFASAMAFVFTLPISIITATTNQTPGLNIITEYAMGLIYPGRPIANVCFKVYGYMSMAQAVSFLNDFKLGHYMKIPPRSMFLVQFIGTILAGTINITVAWWQLNSIKNICQEELLPPNSPWTCPGDRVFFDASVIWGLVGPKRIFGSQGNYAAMNWFFLGGALGPVIVWSLHKAFPKRSWIPLVNLPVLLGATAMMPPATAVNYNSWILVGTIFNLFVFRYRKSWWQRYNYVLSAAMDAGVAFMAVLLYFSVGMEEKSLDWWG----TRGEHCDLAKCPTARGVIVDGCPVK-", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 247, "similar_positions": 262, "identity": "30.27%" }, { "cls_id": "homologset.oma.818063", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6JAM9-1", "uniprot_id": "NACHO_RAT", "id": "Q6JAM9-1", "name": "Novel acetylcholine receptor chaperone", "aln": "MASPRTITIVALSVALGLFFVFMGTIKLTPRLSKDAYSEMKRAYKSYVRALPLLKKMGINSILLRKSIGALEVACGIVMTLVPGRPKDVANFFLLLLVLAVLFFHQLVGDPLKRYAHALVFGILLTCRLLIARKPEDRSSEKKALP------------ESAEEQPSLYEKAPQGKVKVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D328-1", "uniprot_id": "NACHO_MOUSE", "id": "Q9D328-1", "name": "Novel acetylcholine receptor chaperone", "aln": "MASPRTITIMALSVALGLFFVFMGTIKLTPRLSKDAYSEMKRAYKSYVRALPLLKKMGINSILLRKSIGALEVACGIVMTLVPGRPKDVANFFLLLLVLAVLFFHQLVGDPLKRYAHALVFGILLTCRLLIARKPEDRSSEKKALP------------ESAEEQPSLYEKAPQGKVKVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53FP2-1", "uniprot_id": "NACHO_HUMAN", "id": "Q53FP2-1", "name": "Novel acetylcholine receptor chaperone", "aln": "MASPRTVTIVALSVALGLFFVFMGTIKLTPRLSKDAYSEMKRAYKSYVRALPLLKKMGINSILLRKSIGALEVACGIVMTLVPGRPKDVANFFLLLLVLAVLFFHQLVGDPLKRYAHALVFGILLTCRLLIARKPEDRSSEKKPLP------------GNAEEQPSLYEKAPQGKVKVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5E9T5-1", "uniprot_id": "NACHO_BOVIN", "id": "Q5E9T5-1", "name": "Novel acetylcholine receptor chaperone", "aln": "MASPRTVTVVALSVALGLFFVFMGTIKLTPRLSKDAYSEMKRAYKSYVRALPLLKKMGINSILLRKSIGALEVACGIVMTLVPGRPKDVANFFLLLLVLAVLFFHQLVGDPLKRYAHALVFGILLTCRLLIARKPEDRSSEKKSSPPGNAG--SDGNAGNTEEQPSLYEKAPQGKMKLS", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "I3LKJ0-1", "uniprot_id": "I3LKJ0_PIG", "id": "I3LKJ0-1", "name": "Novel acetylcholine receptor chaperone", "aln": "MASPRTVTVVALSVALGLFFVFMGTIKLTPRLSKDAYNEMKRAYKSYVRALPLLKKMGINSILLRKSIGALEVACGIVMTLVPGRPKDVANFFLLLLVLAVLFFHQLVGDPLKRYAHALVFGILLTCRLLIARKPEDRSSEKKSSPPGNAGGATASNAGNTEEQPTLYEKAPQGKMKLS", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q58EL2-1", "uniprot_id": "NACHO_DANRE", "id": "Q58EL2-1", "name": "Novel acetylcholine receptor chaperone", "aln": "MASPRTVTIVALSFALGLFFVFMGTIKLTPRLSKDAYSEMKRAYKSYAKALPALKKMGVSSVLLRKIIGTLEVGCGIVLTLVPGRPKDVANFILLLVMLAVLFFHQLVGDPLKRYAHALVFGILLTCRLLIARQAEDRP-ERE---------------ERREEQINAQEKN---KVKVS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:*::***.***********************.*********.:*** *****:.*:**** **:***.****:*************:***::***********************************:.***. *:: *** . ** *:*:*", "identical_positions": 127, "similar_positions": 24, "identity": "70.95%" }, { "cls_id": "homologset.oma.818064", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYP5-1", "uniprot_id": "TM35B_RAT", "id": "D3ZYP5-1", "name": "Transmembrane protein 35B", "aln": "MLVSLGALRVLLGIFFTLTGAAKL-FQVSAPVSQQMKALFEQFAEVFPLKVLGYQPDPISYQAAVGWLELLAGLLLVVGPPVLQQISNVLLILLMMGAVFTLVVLEESLSTYIPAVVCLGLLLLLDSCQFLVRTKGAVRCRN-KIPGALGNPRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U0Y2-1", "uniprot_id": "TM35B_MOUSE", "id": "Q3U0Y2-1", "name": "Transmembrane protein 35B", "aln": "MSFRVGVLRVLLGVFFALTGAAKL-FQVSAPVSQQMRALFEQFAEVFPLKVFGYQPDPISYQTAVGWLELLAGLLLVVGPPVLQEISNVLLILLMMGAVFTLVVLKEPLSTYVPAAVCLGLLLLLDSCHFLARTKGAVRCPSKKIPPAHGN---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCS4-1", "uniprot_id": "TM35B_HUMAN", "id": "Q8NCS4-1", "name": "Transmembrane protein 35B", "aln": "MALLLSVLRVLLGGFFALVGLAKLSEEISAPVSERMNALFVQFAEVFPLKVFGYQPDPLNYQIAVGFLELLAGLLLVMGPPMLQEISNLFLILLMMGAIFTLAALKESLSTCIPAIVCLGFLLLLNVGQLLAQTKKVVRPTRKKTLSTFKESWK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . :..****** **:*.* *** ::*****::*.*** **********:******:.** ***:**********:***:**:***::********:***..*:*.*** :** ****:****: ::*.:** .** * : : ", "identical_positions": 94, "similar_positions": 35, "identity": "61.04%" }, { "cls_id": "homologset.oma.818078", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9HCC9-1", "uniprot_id": "LST2_HUMAN", "id": "Q9HCC9-1", "name": "Lateral signaling target protein 2 homolog", "aln": "MMNRFRKWLYKPKRSDPQLLARFYYADEELNQVAAELDSLDGRKDPQRCTLLVSQFRSCQDNVLNIINQIMDECIPQDRAPRDFCVKFPEEIRHDNLAGQLWFGAECLAAGSIIMNRELESMAMRPLAKELTRSLEDVRGALRDQALRDLNTYTEKMREALRHFDVLFAEFELSYVSAMVPVKSPREYYVQQEVIVLFCETVERALDFGYLTQDMIDDYEPALMFSIPRLAIVCGLVVYADGPLNLDRKVEDMSELFRPFHTLLRKIRDLLQTLTEEELHTLERNLCISQDVEFPIRADVQGPAALAPALSAPLPPEGPLSAKAKDPDAELACSMQYDDQELEQLSRMVHRAGDEMSSLLSPPIACQSPAHRPGAEGSPGGEASPGRPRLRSGSDEEERVFFMDDVEGTAEALARPESPAGPFGWAGSTWADPQEKGQGGPGGAAGISLPASEKEEDLSNNNLEAEGTDGASLAGTSSCSCLDSRLHLDGWEVGADDAETAEMIAHRTGGMKLSATVIFNPKSPTSLDSAVATQEAAS------EPVAEGMDGGPHKLSTGATNCLLHSCVCCGSCGDSREDVVERLREKCSPGGVIGAS-YAAGLAKASDRAPERQEEAPP-----PSEDASNGREPKAPTSDKCLPHTSGSQVDTASGLQGEAGVAGQQEPEAR--------ELHAGSPS---AHEAPQALSGSSSSTAGSCSSDKMGPEAAPAATHAAPQATREKIRSRFHGSHDLIHRLFVCISGVADQLQTNYASDLRSILKTLFEVMATKPETDDKEKLRKVTQTLRSAALEDCALCQETLSSSELAAKTRDGDFEDPPEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCYMFHVTPFYSDKAGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZPK7-1", "uniprot_id": "LST2_MOUSE", "id": "Q6ZPK7-1", "name": "Lateral signaling target protein 2 homolog", "aln": "MMNRFRKWLYKPKRSDPQLLAQFYYADEELNQVAAELDSLDGRKEPQRCTLLVSQFRSCQDNVLNIINQIMEECIPQDRAPRDFCVKFPEEIRHDNLAGQLWFGAECLAAGSIIMNRELESMAMRPLAKELTRSLEDVRGTLRDQALRDLNTYTEKMREALRRFDVLFAEFELSYVSAMVPVKSPREYYVQQEVIVLFCETVERALDFGYLTQDMIDDYEPALMFTIPRLAIVCGLVVYADGPLNLDRKVEDMSELFRPFHTLLRKIRDLLQALTEEELHTLERSLCVSQDVELPIRADTQAPSALAPTFSASLPPEETLSASANNPEAELACSMQYDDQELEELSRMVHRAGDEMSSLLSPPSACQSPAHRPGSEASPRGEASPARARLKSGSDEEERVFFMDDVE-VTESPARPESPGNTFELTQG---NAQQRGQDGQSGEVGVEAPALVKEEDWSNNNVEGDKIKLASLMGSTSCSCLDSQLYLDGWEVSAEDAETAEMIAHRTGGMKLSATVIFNPKSPTSQDSAVAAQEAPGHGTSPLEPRAEGTGDNSHKLSTTATNCLLHSCVCCGSCGDSRDDAVERLREKCGPGSVISASNPSVSLAKGGDKEPERIDEAQPSDVTLPAEDASNRQEPKAPASSKCLAHTSGPQVDTASRLQGEGEVKGQPEPEARKQDPEKSPVVSGDSPRGDVAQTEHQHLLGSSS-TVGSCSLDNTRLDVATAAMPVTPMATREKIRSRFHGSHDLIHRLFVCISGVADQLQTNYASDLRSILKTLFEVMATKPETDDKEKLKKVTQTLRSAALEDCALCQETVSSSELAAKTRDGDFEDPPEWVPDEACGFCTSCKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCYMFHVTPFYSDKTGM", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********************:**********************:**************************:********************************************************************:*********************:**************************************************************:**********************************************:***********.**:*****:*****.*.*:****::**.**** .***.*::*:***************:******************* **********:*.** *****.*.**:**************** .:*: ******...* : . :.*::**.* .* .*:. ** **** ****:*.: . *** *::*******:*:******.*:****************************** *****:***.. ** *** ....***** *******************:*.********.**.**.** :..***..*: *** :** * *:***** :*****:*.***.****.****** ****. * ** ***** : ..** *: * * **** *.**** *: :.*.** .:* **************************************************************:********************:******************************:***********************************************************:*:", "identical_positions": 741, "similar_positions": 96, "identity": "81.43%" }, { "cls_id": "homologset.oma.818079", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZMR3-1", "uniprot_id": "A0A8I5ZMR3_RAT", "id": "A0A8I5ZMR3-1", "name": "Lateral signaling target protein 2 homolog", "aln": "------MMNRFR-KWLYKPKRSDPQLLAQFYYADEELNQVAAELDSLDGRKEPQRCTLLVSQFRSCQDNVLNIINQIMEECIPQDRAPRDFCVKFPEEIRHDNLAGQLWFGAECLAAGSIIMNRELESMAMRPLAKELTRSLEDVRGTLRDQALRD------------LNTYTEKMREALRRFDVLFAEFELSYVSAMVPVKSPREYYVQQEVIVLFCETVERALEFGYLTQDMIDDYEPALMFTIPRLAIVCGLVVYADGPLNLDRKVEDMSELFRPFHTLLRKIRDLLQALTEEELHTLERSLCVSQDVELPIRADAQAPSALAP--SFSASLAPEETLSASANNPEEELACSMQYDDQELEELSRMVHRAGDEMSSLLSPPSACQSPAHRAGSEASPRGEASPARAQLKSGSDEEERVFFMDDVEVT-ESPARPESPRSTFELTQG-NVQQRGQDGQSGEVGVRAPALVKEE---------DWSNNNIEGDKIKLASLAGSTSCSCL---DSQLYLDGWEVSAEDAETAEMIAHRTGGMKLSATVIFNPKSPTSLDSAAASQEVPGHSISPLEPRAEGTGDNTHKLSTTATNCLLHSCVCCGSCGDSREDAVECLREKCGPGSVLSASNPSVS-----LAKGGEKEPERLEEAQPSDVTLPAEDASSRQEPKAPASNKCLAHTSGPQVDTASRLQGESEVKGQPEP--EARKQDSEKSPVVSGDSPR----GDTAQTEPQHLSGSRAGDRTQG------------------------LALPSSTTGSCSLDSTRLEVTTAVMPVTPMATREKIR-SRFHGSHDLIHRLFVCISGVADQLQTNYASDLRSILKT--LFEVMATKPETDDKEKLKKVTQSLRSAALEDCALCQETVSSSELAAKTRDGDFEDPPEWVPDEACGVCTSCKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCYMFHVTPFYSDKTGM----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8V0Z1R1-1", "uniprot_id": "A0A8V0Z1R1_CHICK", "id": "A0A8V0Z1R1-1", "name": "Lateral signaling target protein 2 homolog", "aln": "MKCVQRISASFPPVWLQRQMRTDPQLLAQFYYADEELNQVAAELDSLDGRKDPQRCTLLVNQFRSCQDNVLNIINQIMDECIPHERANRDFCVKFPEEIRHDNLAGQLWFGAECLAAGSIIMNREIESMAMRPLAKDLTRSLEEVRNIIRDQALRD------------LNLYTEKMKDSLKHFDVLFAEFELSYVSAMVPVKSPKEYYVQQEVIVLFCETVERALRLGYLTQDMIDDYEPALMFTIPRLAIVCGLVVYSEGPLNLDHKPEDMSELFRPFHTLLRKIRDLLQTLTEDELHTLERNLCISQDVDFPVRTDPEVPSVITP--GITATLP-AKELSAKAENTEAELACSMQYDEQELEQLNRMVHRVGDEMSSLLSPPSICQSPAHRPSLRNSSSAEASPTRHHLDNLTDEEDRVFFMDDLDGAGEALAGLDSVSDTFAWVNN-PCHNSKQNLQYRDALLYENGQQTEETLLLKDAESDVSNNNNIEDNKQMSGISVQNSCSCLEGPDSQLYLNGWDAYADDAEMAEMIAHRTGGMKISATVIFNPKSPSSSESPVTPEAAINCVPGSANPLANEEEDESHKLSIAATNCLINSCVCCGSCEDSREESVEGLKTKHSAGGVVNASYTLVKSKEMDHVDNLDNSVPAQETLKPETSALLAERDFGREEQNLPVSSKCLAHSSGSQVGAENDSQGEAESTSSQQKRWEKRKQLCERKVENNEDAGS----ETTAKEDTKSRSSSSSQDGLRDSPLSSISSSDYESVSVTTCSLSSIYALSSLMTSSCSSDDIDQEEIQLALQAAKIATREKIR-SRFHGSNDLIHRLFVCISGVADQLQTNYASDLRSILKT--LFEVMATKPETEDKEKQKKVNQGLRNAALEDCALCQESISSSELAAKARDGDFEDPPDWVPDEVCSYCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQMKPVRVCTHCYMFHVTPFYSDKAGI----------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9VB70-1", "uniprot_id": "LST2_DROME", "id": "Q9VB70-1", "name": "Lateral signaling target protein 2 homolog", "aln": "-------MDTFK-RWLNKPKADDKSLLARFFHADRSLTAVASELDSFDGRAEPDRCTRLVSRLRQNQDKVLAITNLIMEELLGEDRDPRAFRAKFPEEVLQENLAGQLWFGAECLAAGSSIMNRETESKEMRPLAQAVTKSLGNVRVLLRDQCLKNNVPNSKTLHLDLNDSTTEQLYESLKIFDRLFAEFELSYVSAMVQVKSRHEYEMQQWIGVLFSETLQRALKIGLLDQEMVDAFDPGLMFSIPRLAIVAGLVVYAKGPLNMDMPGDQLSEMFRPFRTILIKIRDLLRNLNNQELYQLEKLLCTNEDINTKVPLGSSSIEAPSPEHSSHPTTSSSQNNNNSSNNNHSSSSTNTTSTTTTTAGTTNTHRTVERLVDQRNNNHNSNSNSSTNPTVEAATLRSPSMLSLSATSTPTASPAPSPTPSHSIASTSSAATSSTNPPADWSDGDDEDEDDDDIDVDEEDIESSDDGTDEEQLLKDIVSADCASGYLIPNTNLGNLLQPQEVPLTDNFVASEDDEYGTAEQQGHQGLEEDEPSTSAAMLAATRTLQRLRLPSSDNEPLAEPTTIKASEEHMQQPSGRHRDSHSHRHHQRHHHHHHHRHPHQHQHRQPHPHRTTRSGRKRCSLEAADPERIQP---DREQNLASGDTSAASSLSDDVSLAMRNTTARLKFKSTENLLHRLFVCIAGVADQLQTNFASDLRQILRSVFLMNMSTAQEEIDIPEKTKESELFEFRASENDVIQESAGSNQSIYSAEEVNPELDNVFSAGGGNQATGQRHSAGASMQRNNTIDLASQPGEGSPSGATTATSRSHVTRSRSLGDQEAASSATSSTAQLRQLEQQQQQQQLQIQLQRQRNNSVGSNTPSSASSTSSSSEQNSPVSARSGSRRRLQSNNETQMPSSATSTSATLSPPAWIPDGKAPRCMACQTPFTAFRRRHHCRNCGGVFCGVCSNASAPLPKYGLTKAVRVCRDCYVREVRSGMGVQGVQSVQSVQASAS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ** : * .***:*::**..*. **:****:*** :*:*** **.::*. **:** * * **:* : .:* * * .*****: ::***************** ***** ** *****: :*:** :** :***.*:: : **:: ::*: ** ************** *** :** :** : ***.**::***.:* * *:*:* ::*.***:*******.*****:.****:* :::**:****:*:* ******: *.::**: **: ** .:*:: : ... .. :* . .: . : . .::* . . : . .. : . :.. . . ...: .. . :. ..* . . . . . : : * .* . :. .: :: : : : .:* . .. : ::..: . . :. : . :. : * *.. ::** :: .* :. .: . .. ::*. : : . . : .. . : .: *. :. .. . .. :* . .* : : . . . . . * : :: . . . .:.. .: *. : ..: : : . : : . : * .: ::*.:: ** *.:: . : : : * : .:*: *: .* :..*.: .. . .. :. .* . *.. .:. :: : . .** *:** . * :*::***.:**:****.** :**. **. *****:** *.**** .**: .* . . : ", "identical_positions": 230, "similar_positions": 285, "identity": "23.0%" }, { "cls_id": "homologset.oma.818088", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P61244-1", "uniprot_id": "MAX_HUMAN", "id": "P61244-1", "name": "Protein max", "aln": "--MSDND-DIEVESDEE--------QPRFQ-----SAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDNSLYTNAKGSTISAFDGGSDSSSESEPEEPQSRKKLRMEAS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28574-1", "uniprot_id": "MAX_MOUSE", "id": "P28574-1", "name": "Protein max", "aln": "--MSDND-DIEVESDEE--------QPRFQ-----SAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDNSLYTNAKGGTISAFDGGSDSSSESEPEEPQSRKKLRMEAS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P91664-1", "uniprot_id": "MAX_DROME", "id": "P91664-1", "name": "Protein max", "aln": "MSMSDDDRDIDIESDEDGDSDTGLGSSRHTNTANFTQAEKRAHHNALERRRRDHIKESFTNLREAVPTLKGEKASRAQILKKTTECIQTMRRKISENQKDIEEIKRQNNIIAKQIQALE-------------SSNGDQFS----EFLSDEEVGSEEADDEDLDQDFSRRNKKMKTFHA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:* **::****: ..*. : *:**********:******:** .**::**:*:**********.*:** ** **** :*:**:::**** :: :*::*** **:.. :: :* : **:.:.:.: :: **:: :*:: ", "identical_positions": 73, "similar_positions": 49, "identity": "41.01%" }, { "cls_id": "homologset.oma.818125", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IYN6-1", "uniprot_id": "UBAD2_HUMAN", "id": "Q8IYN6-1", "name": "UBA-like domain-containing protein 2", "aln": "MSVNMDELRHQVMINQFVLAAGCAADQAKQLLQAAHWQFETALSTFFQETNIPNSHHHHQMMCTPSNTPATPPNFPDALAMFSKLRASEGLQSSNS-PMTAAACSPP-ANFSPFWASSPPSHQAPWIPPSSPT----TFHHLHRPQPTWPPGAQQGGAQQ--KAMAAMDGQR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I3LEC8-1", "uniprot_id": "I3LEC8_PIG", "id": "I3LEC8-1", "name": "", "aln": "MSVNMDELRHQVMINQFVLAAGCAADQAKQLLQAAHWQFETALSTFFQETNIPNSHHHHQMMGTPSNTPATPPNFPDALAMFSKLRASEGLQNGSS-PMTAVACSPP-ANFSPFWASSPPSHQAAWIPPSSPTAH--SFHHLHHPQPTWPPGAQQAGPPQ--KAMAAVDGQR--", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q8BQH4-1", "uniprot_id": "UBAD2_MOUSE", "id": "Q8BQH4-1", "name": "UBA-like domain-containing protein 2", "aln": "MSVNTDELRHQVMINQFVLAAGCAADQAQQLLQAAHWQFETALSTFFQESNIPNSHHHPQMMCTPSNTPATPPNFPDALAMFSKLRTSEGLQSSSSSPMAAVACSPP-ANFSPFWAASPPNHQVPWIPPSSPN-----TFHLHCPQPTWPPGASQGGAPQ--KAMAAMDGQR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1D5P876-1", "uniprot_id": "A0A1D5P876_CHICK", "id": "A0A1D5P876-1", "name": "", "aln": "MSVNMEELRHQVMINQFVLAAGCAADQAKQLLQAAHWQFETALSAFFQETNIPNSHHHHQMMCTPSNTPATPPNFPDALAMFSKLRTSENLQSSNS-PITSMACSPP-GSFSPFWASSPPSQQPSWLPPSSPTAHG-LHHHLHHPQPSWPPAPPPAAPPQ--KAMATMDGQR--", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "A0A8I6AE11-1", "uniprot_id": "A0A8I6AE11_RAT", "id": "A0A8I6AE11-1", "name": "UBA-like domain-containing protein", "aln": "----MSELRHDVMIHQFVLAVGCVADQAQQLLQAAHWQFQTALSTFFQESNIPNSHHHPQLMCTPSNTPATPPNFPDALAMFSKLQTSEGLQSSSS-PMTAVACSPPPANLSPFWAASPPNTRWSQKGPQNHGLSTPLLVDNFHLCWWWPLVDSETCHPITSKVCRAEDLAALW", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .****:***:*****.**.****:**********:****:****:******** *:* **********************::**.**...* *::: ***** ..:*****:***. : . *.. . . ** *. : * ", "identical_positions": 92, "similar_positions": 32, "identity": "52.87%" }, { "cls_id": "homologset.oma.818126", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AXN0-1", "uniprot_id": "UBAD1_RAT", "id": "Q6AXN0-1", "name": "UBA-like domain-containing protein 1", "aln": "MSVNMDELKHQVMINQFVLTAGCAADQAKQLLQAAHWQFETALSAFFQETNIPYS-HHHQMMCTPANTPATPPNFPDALTMFSRLKASESFHSGGSSGSPMATSATSPPPHFPH-ATGSFATPSWPTAASPPGGPQHLQPQ-PPLWTPAPPSPTSDWPPLAPQQATSEPRAHPAMEAER", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P3B2-1", "uniprot_id": "UBAD1_MOUSE", "id": "Q6P3B2-1", "name": "UBA-like domain-containing protein 1", "aln": "MSVNMDELKHQVMINQFVLTAGCAADQAKQLLQAAHWQFETALSTFFQETNIPYS-HHHQMMCTPANTPATPPNFPDALTMFSRLKASESFHGGGGSSSPMATSATSPPPHFPH-ATGSFATPSWPTAASPPGGPQQHQPQ-PPLWTPAPPSPTSDWPPLAPQQATSEPRAHPAMEAER", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TB05-1", "uniprot_id": "UBAD1_HUMAN", "id": "Q8TB05-1", "name": "UBA-like domain-containing protein 1", "aln": "MSVNMDELKHQVMINQFVLTAGCAADQAKQLLQAAHWQFETALSAFFQETNIPYSHHHHQMMCTPANTPATPPNFPDALTMFSRLKASESFHSGG-SGSPMAATATSPPPHFPHAATSSSAASSWPTAASPPGGPQHHQPQ-PPLWTPTPPSPASDWPPLAPQQATSEPRAHPAMEAER", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I3LRX1-1", "uniprot_id": "I3LRX1_PIG", "id": "I3LRX1-1", "name": "", "aln": "MSVNMDELKHQVMINQFVLTAGCAADQAKQLLQAAHWQFETALSAFFQETNIPYSHHHHQMMCTPANTPATPPNFPDALTMFSRLKASESFHSGG-SGSPMAATATSPPPHFPHAATGSFSAPGWPTAASPPGGPQHHPLQQPPLWTPAPASPASDWPPLVPQQAASDPRAHPAMEAER", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q6DGM1-1", "uniprot_id": "UBAD1_DANRE", "id": "Q6DGM1-1", "name": "UBA-like domain-containing protein 1", "aln": "----MDELKHQVMINQFVLTAGCAADQAKQLLQAAHWQFETALSAFFQETNIPYG-HHHQMMCTPANTPATPPNFPDALTMFSRLKASESFNSSS---SPSMATSPPPPP------------VSWGMAP-PMANQQSLWTQGPSAQQTHPPP---GWPSAVNQQAASEQKASAAMEAER", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****************************************:*********. ***********************************:... ** :::..*** .* *. * .. * * *. . *.. .**. . ***:*: :* .******", "identical_positions": 109, "similar_positions": 26, "identity": "60.89%" }, { "cls_id": "homologset.oma.818201", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q2TBJ0-1", "uniprot_id": "NOPC1_BOVIN", "id": "Q2TBJ0-1", "name": "NOP protein chaperone 1", "aln": "MEVSGESHSGPSCSSSSRDGSGVSVSKELLMAGSGGRGGIWDRLFINSKPNSRKNSTLQTVRIERSPLLDQVRTFLPQMAQANEKLRKEMAAAPPGHFNIENTDETLGQVIQMDVALFEMNQS-HSKEEDSSEENSQDSSEESSESEDEDDSTSSEGEVTIDNIKLPHSEDGKGKIEVLDSPASENKEKQENK", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "I3LPE1-1", "uniprot_id": "I3LPE1_PIG", "id": "I3LPE1-1", "name": "", "aln": "MEVQSESQSGPTCSSSSQNHSGVSVSKELLTAGSGDQGGIWDKLLINSKPNSRKNSTLQTVRIERSPLLDRVQTFLPQMAQANEQLRKEMAAAPPGCFNIENIDETLGKVIQMDVALFEMNPS-DSKEEDSSEENSQDSS----ASEDEDDSTSSEGEITIDNIKLPHSEAGKGKIEVLDSPDSEKKETGK--", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q8N5I9-1", "uniprot_id": "NOPC1_HUMAN", "id": "Q8N5I9-1", "name": "NOP protein chaperone 1", "aln": "MEVHGKPKASPSCSSPTRDSSGVPVSKELLTAGSDGRGGIWDRLLINSQPKSRKTSTLQTVRIERSPLLDQVQTFLPQMARANEKLRKEMAAAPPGRFNIENIDGPHSKVIQMDVALFEMNQS-DSKEVDSSEESSQDSSENSSESEDEDDSIPS--EVTIDNIKLPNSEGGKGKIEVLDSPASKKKK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1M6B3-1", "uniprot_id": "F1M6B3_RAT", "id": "F1M6B3-1", "name": "", "aln": "MALRGEHASGPGVSSSSVDCSRITVSRELLTAGSEGSRGVWDQLLINSKPHSRKASTLQTVRVQRSPLLDQVQAFLPQMAQANEKLRKEMAVAPAGHFNIENIDETSGNIIQMDVALFEMNQSEDSKEDDNPEESSQDSSGDSSESED-DDCIPS--EVTIENIKLPNTEGGKGKIQVLDSPASKKKKQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CX66-1", "uniprot_id": "NOPC1_MOUSE", "id": "Q9CX66-1", "name": "NOP protein chaperone 1", "aln": "MEFQGERGTGPGVSSSSVACSQVTVSRELLTAGSEGSGGIWDQLLISSKPHPRKTSTLQTVRMQRSPLLDQVQAFLPQMAQANEKLRREMAAAPAGHFNIENIDETSGNIIQMDVALFEMSRS-DSKEEDSPEESSRDSSGDSSESEE-DVCVPS--EVTIENIKLPNAEGGKGKIEILDSPASKKKKQ----", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . .: :.* **.: * :.**:*** *** . *:**:*:*.*:*:.** *******::******:*::******:***:**:***.**.* ***** * . .::**********. * .*** *..**.*:*** **: * . .* *:**:*****::* *****::**** *::*: ", "identical_positions": 104, "similar_positions": 50, "identity": "53.89%" }, { "cls_id": "homologset.oma.818217", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P78406-1", "uniprot_id": "RAE1L_HUMAN", "id": "P78406-1", "name": "mRNA export factor RAE1", "aln": "-------------------------------------------------------------MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAGSWANDVRCWEVQDSGQ---TIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSN-QAIQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSN--PMMVLQLPERCYCADVIYPMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRVAIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQ-KKNYIFLRN---AAEELKPRNKK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5GFN6-1", "uniprot_id": "RAEL1_PIG", "id": "A5GFN6-1", "name": "mRNA export factor", "aln": "-------------------------------------------------------------MSLFGTTSGFGTSGTSMFGSTTTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAGSWANDVRCWEVQDSGQ---TIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLNSN-QAIQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSN--PMMVLQLPERCYCADVIYPMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRVAIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQ-KKNYIFLRN---AAEELKPRNKK----", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q5E9A4-1", "uniprot_id": "RAE1L_BOVIN", "id": "Q5E9A4-1", "name": "mRNA export factor", "aln": "-------------------------------------------------------------MSLFGTTSGFGSGGTSMFGSTTTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAGSWANDVRCWEVQDSGQ---TIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLNSN-QAIQIAQHDAPVKTVHWIKAPNYSCVMTGSWDKTLKFWDTRSSN--PMMVLQLPERCYCADVIYPMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRVAIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQ-KKNYIFLRN---AAEELKPRNKK----", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q8C570-1", "uniprot_id": "RAE1L_MOUSE", "id": "Q8C570-1", "name": "mRNA export factor", "aln": "-------------------------------------------------------------MSLFGSTSGFGTGGTSMFGSTTTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAGSWANDVRCWEVQDSGQ---TIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLNSN-QAIQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSN--PMMVLQLPERCYCADVIYPMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRVAIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQLDQPIAACCFNHNGNIFAYASSYDWSKGHEFYNPQ-KKNYIFLRN---AAEELKPRNKK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3HBL0-1", "uniprot_id": "G3HBL0_CRIGR", "id": "G3HBL0-1", "name": "mRNA export factor", "aln": "-------------------------------------------------------------MSLFGSASGFGTGGTSMFGSTATDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAGSWANDVRCWEVQDSGQ---TIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLNSN-QAIQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSN--PMMVLQLPERCYCADVIYPMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRVAIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQLDQPIAACCFNHNGNIFAYASSYDWSKGHEFYNPQ-KKNYIFLRN---AAEELKPRNKK----", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "A0A8V0YXB8-1", "uniprot_id": "A0A8V0YXB8_CHICK", "id": "A0A8V0YXB8-1", "name": "Rae1 protein homolog", "aln": "MREKQLRTRRPQSAVPTPAAGAPAPPPPLCSRRLRREARPAPCAALRRAVSREVSSAVRTRMSLFGSTSGFGTGGTSMFGSTTADNHNPMKDIEVTSPPDDSISCLAFSPPTLPGNFLIAGSWANDVRCWEVQDNGQ---TIPKAQQMHTGPVLDGCWSDDGSKVFTASCDKTAKMWDLNSN-QAIQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSPT--PMMTLQLPERCYCADVVHPMAAVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKVNKPTGFALGSIEGRVAIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQ-KKNYIFLRN---AAEELKPRNKK----", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q7ZWF0-1", "uniprot_id": "RAE1L_DANRE", "id": "Q7ZWF0-1", "name": "mRNA export factor", "aln": "-------------------------------------------------------------MSLFGTNTGFGSGGTGVFGSTTTDSHNPMKDVEVTSPPDDSISCLAFSPPTMPGNFLIGGSWANDVRCWEVQDNGQ---TVPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLNSN-QAIQIAQHEGPIRTIHWIKAPNYSCIMTGSWDKTLKFWDTRSPN--PMMSLQMPERCYCADVVYPMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQSKPTGFALGSIEGRVAIHYINPPNPAKDNFTFKCHRSNGTNTATPQDIYAVNAISFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQLDQPITACCFNHNGNIFAYASSYDWSKGHEYYNPQ-KKNYIFLRN---AAEELKPRNKK----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2E7-1", "uniprot_id": "RAE1_DROME", "id": "Q9W2E7-1", "name": "Protein Rae1", "aln": "-----------------------------------------------------------------------------MFGATQSTNR--MNDFEVASPPDDSVSALEFSPSTVQKNFLVAGSWDSTVRCWEVEQNGA---TVPKSMKTMGGPVLDVCWSDDGSKVFVASCDKQVKLWDLASD-QVMQVAAHDGPVKTCHMVKGPTYTCLMTGSWDKTLKFWDTRSPN--PMMTINLPERCYCADVEYPMAVVGTANRGLIIYSLQNSPTEYKRQESPLKYQHRAISIFRDKKKEPTGCALGSIEGRVAIQYVNPGNP-KDNFTFKCHRTTG--TSGYQDIYAVNDIAFHPVHGTLVTVGSDGTFSFWDKDARTKLKSSETMDQSITKCGFNANGQIFAYAVGYDWSKGHEYFNPA-KKPQIFLRS---CYDELKPRIN-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q38942-1", "uniprot_id": "RAE1_ARATH", "id": "Q38942-1", "name": "Protein RAE1", "aln": "---------------------------------------------------------------------------MATFGAPATANSNPNKSYEVTPSPADSISSLSFSP---RADILVATSWDNQVRCWEISRSGASLASAPKASISHDQPVLCSAWKDDGTTVFSGGCDKQAKMWPLLSGGQPVTVAMHEGPIAAMAWIPG--MNLLATGSWDKTLKYWDTRQQN--PVHTQQLPDKCYTLSVKHPLMVVGTADRNLIVFNLQNPQTEFKRIQSPLKYQTRCVTAFPDQQ----GFLVGSIEGRVGVHHLD-DSQQSKNFTFKCHRDGN-------DIYSVNSLNFHPVHGTFATAGSDGAFNFWDKDSKQRLKAMSRCNQPIPCSSFNHDGSIYAYAACYDWSKGAENHNPATAKSSIFLHLPQESEVKAKPRVGATGRK", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q54QH0-1", "uniprot_id": "Q54QH0_DICDI", "id": "Q54QH0-1", "name": "", "aln": "-----------------------------------------------------------------------------MFSTSTTTNPN--NDIELSSPPSDGVSCLKFSP--KANNFIVAGSWDQKVRCWEINPSTKS--SMPKAIISHDAAILCTDWSGDGTKVFTGGVDGKGKCWNLATN-QMVQVAQHTAPIKECFWIEE--SNVLVTASWDKTLKYWDTRQQTGTPVLSLELTERIYAMDMLYPLLAVATADKKIYIYDLKNPQSPYKTVDSLLKFQTRCISCFPDKS----GFALGSIEGRVAIQSLD-DSKQENSFTFKCHREND------TVAYAVNNISFALPYGTFATAGSDGGFSFWDKESKFRLKQFSKLPQSISTATFNLDASLYAYASSYDWSKGSQYFDPN-QPNSIFVRV---VGDEAKKGNRQTKKR", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.:. : . :. *::..* *.:..* *** ::::. ** . *****:. . : **: .:* *..**:.** .. * * * * :. * : :* * .*: : . : *.*******:****. . *: ::.:: * .: :*: .*.**:: : ::.*:* : :: :* **.* *.:: * *: * :*******.:: :: . ...******* . *:** : * :**:.*.**** *.****::: :** . *.*. . ** :..::*** ****** : .:* **:: : * ", "identical_positions": 108, "similar_positions": 112, "identity": "24.38%" }, { "cls_id": "homologset.oma.818218", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A9J7JEA0-1", "uniprot_id": "A0A9J7JEA0_CRIGR", "id": "A0A9J7JEA0-1", "name": "Mitotic checkpoint protein BUB3", "aln": "-----------------------MTGSNEFKLNQPPEDGISSVKFSPNTSQFLLVSSWDTSVRLYDVPANSMRLKYQHTGAVLDCAFYDPTHAWSGGLDHQLKMHDLNTDQENLVGTHDAPIRCVEYCPEVNVMVTGSWDQTVKLWDPR-----TPCNAGTFS-QPEK-VYTLSVSGDRLIVGTAGRRVLVWDLRNMGYVQQRRESSLKYQTRCIRAFPNKQGYVLSSIEGRVAVEYLDPSPEVQKKKYAFKCHRLKENNIEQIYPVNAISFHNIHNTFATGGSDGFVNIWDPFNKKRLCQFHRYPTSIASLAFSNDGTTLAIASSYMYEMDDT--EHPEDGIFIRQVTDAETKPKSSKEILRKYL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q1JQB2-1", "uniprot_id": "BUB3_BOVIN", "id": "Q1JQB2-1", "name": "Mitotic checkpoint protein BUB3", "aln": "-----------------------MTGSNEFKLNQPPEDGISSVKFSPNTSQFLLVSSWDTSVRLYDVPANSMRLKYQHTGAVLDCAFYDPTHAWSGGLDHQLKMHDLNTDQENLVGTHDAPIRCVEYCPEVNVMVTGSWDQTVKLWDPR-----TPCNAGTFS-QPEK-VYTLSVSGDRLIVGTAGRRVLVWDLRNMGYVQQRRESSLKYQTRCIRAFPNKQGYVLSSIEGRVAVEYLDPSPEVQKKKYAFKCHRLKENNIEQIYPVNAISFHNIHNTFATGGSDGFVNIWDPFNKKRLCQFHRYPTSIASLAFSNDGTTLAIASSYMYEMDDT--EHPEDGIFIRQVTDAETKPKST----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q9WVA3-1", "uniprot_id": "BUB3_MOUSE", "id": "Q9WVA3-1", "name": "Mitotic checkpoint protein BUB3", "aln": "-----------------------MTGSNEFKLNQPPEDGISSVKFSPNTSQFLLVSSWDTSVRLYDVPANSMRLKYQHTGAVLDCAFYDPTHAWSGGLDHQLKMHDLNTDQENLVGTHDAPIRCVEYCPEVNVMVTGSWDQTVKLWDPR-----TPCNAGTFS-QPEK-VYTLSVSGDRLIVGTAGRRVLVWDLRNMGYVQQRRESSLKYQTRCIRAFPNKQGYVLSSIEGRVAVEYLDPSPEVQKKKYAFKCHRLKENNIEQIYPVNAISFHNIHNTFATGGSDGFVNIWDPFNKKRLCQFHRYPTSIASLAFSNDGTTLAIASSYMYEMDDT--EHPEDGIFIRQVTDAETKPKST----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43684-1", "uniprot_id": "BUB3_HUMAN", "id": "O43684-1", "name": "Mitotic checkpoint protein BUB3", "aln": "-----------------------MTGSNEFKLNQPPEDGISSVKFSPNTSQFLLVSSWDTSVRLYDVPANSMRLKYQHTGAVLDCAFYDPTHAWSGGLDHQLKMHDLNTDQENLVGTHDAPIRCVEYCPEVNVMVTGSWDQTVKLWDPR-----TPCNAGTFS-QPEK-VYTLSVSGDRLIVGTAGRRVLVWDLRNMGYVQQRRESSLKYQTRCIRAFPNKQGYVLSSIEGRVAVEYLDPSPEVQKKKYAFKCHRLKENNIEQIYPVNAISFHNIHNTFATGGSDGFVNIWDPFNKKRLCQFHRYPTSIASLAFSNDGTTLAIASSYMYEMDDT--EHPEDGIFIRQVTDAETKPKSPCT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A567-1", "uniprot_id": "D4A567_RAT", "id": "D4A567-1", "name": "", "aln": "MAAGLDQGGPARCAGAGPAFVLQMTGSNEFKLNQPPEDGISSVKFSPNTSQFLLVSSWDTSVRLYDVPANSMRLKYQHTGAVLDCAFY----------------------VENLVGTHDAPIRCVEYCPEVNVMVTGSWDQTVKLWDPR-----TPCNAGTFS-QPE------------------------------------------------------KGYVLSSIEGRVAVEYLDPSPEVQKKKYAFKCHRLKENNIEQIYPVN-----------------------------RLCQFHRYPTSIASLAFSNDGTTLAIASSYMYEMDDT--EHPEDGIFIRQVTDAETKPKSSRKSSVNICGLSQDGHRLAASSWRLAVPGLWSSRIPVLTIPPSADTAKRQAPLDIATNCYSKFPDVHTAVTLVASMHKSRTGVITLLVFVTTYLMRSTIKEESLLLLVVKGGKVHHGGEGKSGSPKSQKHFLLALQFFIWHNSNSNNNNNSNNNNSNNNNSNNNNNSNNSSSNNSNSNNSNSNNSSSNSTSNNSNSNNSNSNNSNNNNNNSNNSNSNNSNSNSNNSNNKNSNNNSNNNNSNSNSNNSNNSSNNSSSSNNSNSNNNSNNSNNSNNSSNNSSSSNNSNNKNNSNNNNSNNNNNSNSSSSNNNSNSNNNSNSSSSNNNSSSNNNSNNNSNNNSNSNNHHHHPGNLAAAPLICIGIFLLLQALKGLNDTML", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VAJ2-1", "uniprot_id": "Q9VAJ2_DROME", "id": "Q9VAJ2-1", "name": "Mitotic checkpoint protein BUB3", "aln": "------------------------MRPPEFKLNNPPEDLISAVKFGPKSNQYMAASSWDGTLRFYDVPANQLRQKFVQDAPLLDCAFMDIVHVVSGSLDNQLRLFDVNTQAESIIGAHEEPIRCVEHAEYVNGILTGSWDNTVKLWDMR-----EKRCVGTFE-QNNGKVYSMSVIDEKIVVATSDRKVLIWDLRKMDSYIMKRESSLKYQTRCIRLFPNKEGYVMSSIEGRVAVEYLDHDPEVQRRKFAFKCHRNREQNIEQIYPVNALSFHNVYQTFATGGSDGIVNIWDGFNKKRLCQFHEYDTSISTLNFSSDGSALAIGCSYLDQLPETPATVPHPAIYIRYPTDQETKQK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9LJN8-1", "uniprot_id": "BUB31_ARATH", "id": "Q9LJN8-1", "name": "Mitotic checkpoint protein BUB3.1", "aln": "--------------------MTTVTPSAGRELSNPPSDGISNLRFS-NNSDHLLVSSWDKRVRLYDVSTNSLKGEFLHGGAVLDCCFHDDFSGFSVGADYKVRRIVFNVGKEDILGTHDKAVRCVEYSYAAGQVITGSWDKTVKCWDPRGASGPERTQVGTYL-QPER-VYSMSLVGHRLVVATAGRHVNIYDLRNMSQPEQRRESSLKYQTRCVRCYPNGTGYALSSVEGRVAMEFFDLSEAAQAKKYAFKCHRKSEAGRDIVYPVNSIAFHPIYGTFATGGCDGFVNIWDGNNKKRLYQYSKYPTSISALSFSRDGQLLAVASSYTFEEGEK--SQEPEAIFVRSVNEIEVKPKPKVYPNPAA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q54DM1-1", "uniprot_id": "BUB3_DICDI", "id": "Q54DM1-1", "name": "Mitotic checkpoint protein bub3", "aln": "--------------------MSNEPTSSFYELRLPPSDGISSVNFCPNSVN-LLVTSWDSTVRCYDTQNNVQKWQYNHKGPVMDGCFPEKNKVFSGDVFGSVKHYDPVAGVEKEVGSHEDGVRSVVYNSDTQQLFTGGWDQQLKLWDIR----SDKMEISNHDLQSKIFTMDVSPISNMLVIGTADKYVTIYDTRQMETHLQKRESSIKYQTRCIRTFTDGKGYALASVEGRIAMEYFDPSPAVQSKKYAFKCHRLTESGVDVVYPVNCIAFNPHYGTFATGGCDKNVFFWDGANRKRLHALKTYPTSISSMSFNTDGNILAVASSYTFEEGEK--DHPPDQIFIHNILSEKIIKPIK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* **.* ** :.* :. : : .:*** :* **. * : :: : ..::* .* *. :*:*: :*.* : . :.**.**: :* ** * ... * : **.::*:***:*:*::* . .* :*:****** * . : :**** ** * ***::: *. ** **:..** : :. *::: . : ", "identical_positions": 66, "similar_positions": 69, "identity": "8.99%" }, { "cls_id": "homologset.oma.818219", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q7ZWF0-1", "uniprot_id": "RAE1L_DANRE", "id": "Q7ZWF0-1", "name": "mRNA export factor", "aln": "MSLFGTNTGFGSGGTGVFGSTTTDSHNPMKDVEVTSPPDDSISCLAFSPPTMPGNFLIGGSWANDVRCWEVQDNGQTVPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLNSNQAIQIAQHEGPIRTIHWIKAP--NYSCIMTGSWDKTLKFWDTRSPNPMMSLQMPERCYCADVVYPMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQSKPTGFALGSIEGRVAIHYINPPNPAKDNFTFKCHRSNGTNTATPQD----IYAVNAISFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQLDQPITACCFNHNGNIFAYASSYDWSKGHEYYNPQKKNYIFLRN-AAEELKPRNKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40066-1", "uniprot_id": "GLE2_YEAST", "id": "P40066-1", "name": "mRNA export factor GLE2", "aln": "MSFFNRSNTTSALGTSTAMANEKDLAN---DIVINSPAEDSISDIAFSP--QQDFMFSASSWDGKVRIWDVQ-NGVPQGRAQHESSSPVLCTRWSNDGTKVASGGCDNALKLYDIASGQTQQIGMHSAPIKVLRFVQCGPSNTECIVTGSWDKTIKYWDMRQPQPVSTVMMPERVYSMDNKQSLLVVATAERHIAIINLANPTTIFKATTSPLKWQTRCVACYN----EADGYAIGSVEGRCSIRYIDDGMQKKSGFSFKCHRQTNPNRAPGSNGQSLVYPVNSIAFHPLYGTFVTAGGDGTFNFWDKNQRHRLKGYPTLQASIPVCSFNRNGSVFAYALSYDWHQGHMGNRPDYPNVIRLHATTDEEVKEKKKR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*. .. .: **.. :. .* * *: :.**.:**** :**** . :: ..** ..** *:** ** . :**: :.*** . **:**:** :..**:: *::*: *.*: **. *..**:.:::::. * .**:*******:*:** *.*:*: :: **** *. * .: ******* : : :* * .: *: **** * **** :: :. *:*:**:*** :*:**: *..*:*****....* *. .: :*.**:*:***::**:.*.*.** *.****: * :** *: .*..*.**:**.:**** **** :** .*: * * *: : **:* ::*:", "identical_positions": 155, "similar_positions": 122, "identity": "41.33%" }, { "cls_id": "homologset.oma.818293", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9P0J6-1", "uniprot_id": "RM36_HUMAN", "id": "Q9P0J6-1", "name": "Large ribosomal subunit protein bL36m", "aln": "MANLFIR----KMVNPLLYLSRHTVKPRALSTFLFGSIRGAAPVAVEPGAAVRSLLSPGLLPHLLPALGFKNKTVLKKRCKDCYLVKRRGRWYVYCKTHPRHKQRQM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3ILF5-1", "uniprot_id": "G3ILF5_CRIGR", "id": "G3ILF5-1", "name": "Ribosomal protein", "aln": "MATLLVRSAVASLMHPLLHLSRFAVRPRAFSSFLLGTLPSAR-----PCAEARSLLWGRPVPHLQLTQGFKTKGVLRKRCRDCYMVKRRGRWFVLCKTNPRHKQRQM", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.*::* .:::***:***.:*:***:*:**:*:: .* * * .**** :*** : ***.* **:***:***:*******:* ***:********", "identical_positions": 59, "similar_positions": 26, "identity": "55.14%" }, { "cls_id": "homologset.oma.818294", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A287A731-1", "uniprot_id": "A0A287A731_PIG", "id": "A0A287A731-1", "name": "Ribosomal protein", "aln": "MATAFLRTVLSAVGPLLHLGGRPLSTFAAGPPRAALAV---GAQPSPAAALLSARPLLGP-QPALGFKTKGVLKKRCRDCYLVKRRGRWFIYCKTNPKHKQRQM", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A8V0XV61-1", "uniprot_id": "A0A8V0XV61_CHICK", "id": "A0A8V0XV61-1", "name": "Ribosomal protein", "aln": "MLSFLAR---VAAGPLRSLGRSPLCSLAPRWRVAAVPVPLCSGEAAPTRALLAGPPPPGLLQLCAGLKTKTSIKRRCKDCYIVRRRGRLYVCCKTNPRHKQRKL", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : * *.*** ** **.::*. **:.* ..:.:*: ***:. * * * . *:*** :*:**:***:*:**** :: *****:****::", "identical_positions": 45, "similar_positions": 29, "identity": "43.27%" }, { "cls_id": "homologset.oma.818317", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q61233-1", "uniprot_id": "PLSL_MOUSE", "id": "Q61233-1", "name": "Plastin-2", "aln": "-------MARGSVSDEEMMELREAFAKVDTDGNGYISCNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGKISFDEFIKVFHGLK--STEVA--KTFRKAINKKEGICAIGG-------------TSEQSSVGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFNAVGDGIVLCKMINLSVPDTIDERTINK----KKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCT-KITNFSTDIK---------DSKAYYHLLEQVAPKGDEEGIPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNPKLNLAFIANLFNKYPALH---KPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIKV-PVDWNRVNKPPYPKLGGN-MKKLENCNYAVDLGKNQAKFSLVGIAGQDLNEGNRTLTLALVWQLMRRYTLNILEDIG-GGQKVNDDIIVNWVNTTLKEAQKSSSIASFKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLDDEEKLNNAKYAISMARKIGARVYALPEDLVEVNPKMVMTVFACLMGKG----MKRV-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8C2MV10-1", "uniprot_id": "A0A8C2MV10_CRIGR", "id": "A0A8C2MV10-1", "name": "", "aln": "-------MARGSVSDEEMMELREAFAKVDTDGNGYISCNELNDLFKAACLPLPGYRVREITENLMATGDLDKDGKISFDEFIKVFHGLK--STEVA--KTFRKAINKKEGICAIGG-------------TSEQSSVGTQHSYSEEEKYAFVNWINKALESDPDCRHVIPMNPNTDDLFNAVGDGIVLCKMVNLSVPDTIDERTINK----KKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCN-KITNFSTDIK---------DSKAYYHLLEQVAPKGDEEGIPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNPKLNLAFIANLFNKYPALH---KPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDLADALIIFQLYEKIKV-PVDWNRVNKPPYPKLGGN-MKKLENCNYAVDLGKNQAKFSLVGIAGQDLNEGNRTLTLALLWQLMRRYTLIMMEDIG-DGQKVNDDIIVNWVNETLKDAQKSSSISSFKDPKISTSLPVLDLIDAIQPGSINYDLIKTENLDEEEKLNNAKYAISMARKIGARVYALPEDLVEVNPKMVMTVFACLMGRG----MKRV-------------", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "P13796-1", "uniprot_id": "PLSL_HUMAN", "id": "P13796-1", "name": "Plastin-2", "aln": "-------MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISFDEFIKIFHGLK--STDVA--KTFRKAINKKEGICAIGG-------------TSEQSSVGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTINK----KKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCN-KIGNFSTDIK---------DSKAYYHLLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNPKLNLAFIANLFNRYPALH---KPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIKV-PVDWNRVNKPPYPKLGGN-MKKLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNILEEIG-GGQKVNDDIIVNWVNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLNDDEKLNNAKYAISMARKIGARVYALPEDLVEVNPKMVMTVFACLMGKG----MKRV-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A287ANV7-1", "uniprot_id": "A0A287ANV7_PIG", "id": "A0A287ANV7-1", "name": "", "aln": "-------MARGSVSDEEMMELREAFAKVDTDGNGYISCNELNDLFKAACLPLPGYRVREITENLMATGDLDRDGRISFDEFIKVFHGLK--STEVA--KTFRKAINKKEGICAIGG-------------TSEQSSVGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMDPNTNDLFSAVGDGIVLCKMINLSVPDTIDERTINK----KKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIELSRNEALAALLREGESLEDLMKLSPEELLLRWANYHLENAGCN-KINNFSSDIKLTDFYSNIKDSKAYYHLLEQVAPKGDEEGIPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNPKLNLAFIANLFNRYPALH---KPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIKV-PVDWNRVNKPPYPKLGGN-MKKLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALVWQLMRRYTLNILEEIG-GGQKVNDDIIVNWVNETLKEAGKSTSISSFKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLNDEEKLNNAKYAISMARKIGARVYALPEDLVEVNPKMVMTVFACLMGRG----MKRV-------------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q6P698-1", "uniprot_id": "PLSL_DANRE", "id": "Q6P698-1", "name": "Plastin-2", "aln": "-------MAAAQISAEEMEELREAFTKVDVDGNGHISTDELNALFKAANLPLPGYRVREIIQEISRTMDLNQDGKITFDEFAKVVHDLK--SSEVA--KTFRKAINKKEGICSVAG-------------TSEQS--GTQHSYSEEEKVAFVNWVNKALEKDPDCQHVLPMDPSTDDLFTAVGDGIVLCKMINLSVPDTIDERTINK----KKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGRQHLVLGLLWQVIKIGLFADIEISRNEALIALLRDGESLEDLVKLSPEELLLRWANYHLEEAGCP-KINNFSSDIK---------DSKAYYNILNQVAPKRDEEGIPAIPIDISGIREKDDLKRAECMLEQADRLGCRQFVTATDVVRGNPKLNLAYVANLFNKYPALK---KPENQDIDWSSIEGETREERTFRNWMNSLGVNPRVNHLYVDLADALVIFQLYEKIKV-PVDWDKVNKPPYPKLGSN-MKKLENCNYAVELGKKEAKFSLVGIAGQDLNEGNRTLTLALLWQLMRRYTLNILEDLG-DGQKIIDETIVQWVNETLTQAGKG-TISGFKDGSISSSMPVLDLIDAIQPGSIRYDLLKAEDLTDEKKLNNAKYAISMARKIGARVYALPEDLVEVKPKMVMTVFACLMARG----MRRI-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQZ7-1", "uniprot_id": "Q8IQZ7_DROME", "id": "Q8IQZ7-1", "name": "", "aln": "-MADILNVEQHQTVQEFKQNLEELIPNLDANKDGFIDLHELKDALNQVGFKLAGYQVREMIDEYKGKQLTAFQGKLNLEEFEALCLDLK--SKDVA--STFKTVVSKKENLETLGG-------------MSSISSEGTTHSVRLEEQLAFSDWINSNLGHDKDLQHLLPIDSEGKRLYLSIKDGILLCKIINHSCPDTIDERAINK----KNLTVYREFENLTLALVSSQAIGCNIVNIDAHDLAKGKPHLVLGLLWQIIRIGLFSHITLDSCPGLAGLLFDNERLEDLMKMSPEAILLRWVNHHLERAGISRRCTNFQSDIV---------DSEIYSHLLKQIAGNDAD-------VNLDALRESDLQSRAEIMLQQAAKLNCRSFLTPQDVVNGVYKLNLAFVANLFNNHPGLD---KPEQ--IEGLESIEETREEKTYRNWMNSMGVAPHVNWLYSDLADGLVIFQLFDVIKPGIVNWSRVHKR-FSPLRKF-MEKLENCNYAVDLG-KQLKFSLVGIAGQDLNDGNATLTLALIWQLMRAYTLSILSRLANTGNPIIEKEIVQWVNNRLSEAGKQSQLRNFNDPAIADGKIVIDLIDAIKEGSINYELVRTSGTQ-EDNLANAKYAISMARKIGARVYALPEDITEVKPKMVMTVFACMMALDYVPNMDSVDQNNHNSSANNSN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54680-1", "uniprot_id": "FIMB_DICDI", "id": "P54680-1", "name": "Fimbrin", "aln": "---------MTNFSESEISEFKASFNQFDENGDGQISALELQKILTKCGEKVTGVEVRDMIKEV----DTDGNGSIDFKEFLQVMQKARQHSANAS--PAFASAVKKVGAVNTIGG-------------YSGSTASGVQHSYSDEEKVAYIDWINNCLAKDVDLKSRLPIPEDGDKFFAACNDGLLLCKLINDAVPDTIDERVLNK----KNLNAFRINENQVLCINSAKAIGCNVVNIGAGDLVEGRAHLIMGLTWQIIKIGLFARINLTNHPELYRLLHDGETIEDLLKLPVEEILLRWFNYHLAAAGSQRRVKNFSGDIK---------DSECYTILLKQIAPKDAG-------VETSALNISNLDQRAVKVLENADKLGCKKFLKPKDIVTGFQKLNLAFVANLFNTHPALE---PVED-----VVIIEETREEKTFRNWMNSLGVDPFVNNLYEGTYDGLILIQLFDKIYPGLVDHKKVNYPPYKAMGAE-MKKIENCNYAIQLG-KDCKYSLVGIDGKNVYDKNKTLTLSILWQLMRGHVISILTALSGSGKPIADADIVNWTNSKLSAAGKK-QISGFKDSTISTGIPILDVIEAVRPGSVDPALVATSGSA-EDNLLNAKLAVSTARKVGAVVFALPEDIVEVKPKMVLTLFASLWQVE----MTK--------------", "tax_id": 44689, "tax_name": "Social amoeba" }, { "uniprot_ac": "P32599-1", "uniprot_id": "FIMB_YEAST", "id": "P32599-1", "name": "Fimbrin", "aln": "MNIVKLQRKFPILTQEDLFSTIEKFRAIDLDDKGWVEKQQALEAVSKDGD-ATYDEARETLKHVG----VDASGRVELDDYVGLVAKLRESKTGAAPQTTFNVAPNSTPIVSTAATGLQHKGKGTQAKIIVAGSQTGTTHTINEEERREFTKHINSVLAGDQDIGDLLPFPTDTFQLFDECRDGLVLSKLINDSVPDTIDTRVLNWPKKGKELNNFQASENANIVINSAKAIGCVVVNVHSEDIIEGREHLILGLIWQIIRRGLLSKIDIKLHPELYRLLEDDETLEQFLRLPPEQILLRWFNYHLKQANWNRRVTNFSKDVS---------DGENYTILLNQLDP---------ALCSKAPLQTTDLMERAEQVLQNAEKLDCRKYLTPSSLVAGNPKLNLAFVAHLFNTHPGLEPIQEEEKPEIEEFDAEGE-REARVFTLWLNSLDVDPPVISLFDDLKDGLILLQAYEKVMPGAVDFKHVNKRPASGAEISRFKALENTNYAVDLG-RAKGFSLVGIEGSDIVDGNKLLTLGLVWQLMRRNISITMKTLSSSGRDMSDSQILKWAQDQVTKGGKNSTIRSFKDQALSNAHFLLDVLNGIAPGYVDYDLVTPGNTE-EERYANARLAISIARKLGALIWLVPEDINEVRARLIITFIASLMTLN------K--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : .* : .* :. : .. . ..*: .. .* : :.:: : : . .: :* . .. : : . : *. *: **: : . :*. * * * :*: . :: **::*.*::* : ***** *.:* *:*. : ** : : *:.**** :**: : *: :*: :*::** **:*: **:: * : * ** :.* :*:::::. * :**** *:** *. : **. *: *.: * :*:*: . :. .: .** :*::* :*.*:.::.. .:* * *****::*:*** :*.*. *. * ** :.: *:**:.* * * *: . *.*:::* :: : *: .:*: :: :** ***::** . :***** *.:: : * ***.::***** : :. *. : : *::*.: : . * : .*:* :: . ::*:::.: * : *: . . :.. **: *:* ***:** :: :***: **..::::*.:*.: ", "identical_positions": 151, "similar_positions": 205, "identity": "21.95%" }, { "cls_id": "homologset.oma.818318", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3V0K9-1", "uniprot_id": "PLSI_MOUSE", "id": "Q3V0K9-1", "name": "Plastin-1", "aln": "-------------------------------------MENSTTTISREELEELQEAFNKIDIDNSGYVSDYELQDLFKEASLPLPGYKVREIVEKILVVADNNKDGKISFEEFVSLMQELKSKDISKTFRKIINKREGITAIGGTSSISSEGTQHSYSEEEKVAFVNWINKALENDADCSHLLPMNPNDGSLFKSLADGILLCKMINLSEPDTIDERAINKKKLTP-FTVSENLNLALNSASAIGCTVVNIGAQDLKEGKPHLVLGLLWQIIKVGLFADIEISRNEALIALLKDGEDLEELMKLSPEELLLRWVNYHLTNAGWR-TINNFSQDIKDSKAYFHLLNQIAPKGDRDDGPAVAIDLSGFNEKNDLKRAGFMLQEADKLGCRQFVTPADVVSGNPKLNLAFVANLFNTYPCLHKPDNNDIDLNLLEGE---SKEERTFRNWMNSLGVNPYINHLYSDLADALVIFQLYEMIR-VPVNWSQVNKPPYPALGGNMKKIENCNYAVELGKNEAKFSLVGIAGQDLNEGNATLTLALVWQLMRRYTLKVLSDL---GEGEKVTDDIIIKWVNQTLKSANKSTSISSFKDKSISTSLPVLDLIDAIAPNAVRQEMIKREHLTDEDKLNNAKYAISVARKIGARIYALPDDLVEVKPKMVMTVFACLMGKGLNRLK---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LXW3-1", "uniprot_id": "A0ABK0LXW3_RAT", "id": "A0ABK0LXW3-1", "name": "", "aln": "-------------------------------------MENSTTTISREELEELQEAFNKIDIDNSGYVSDYELQDLFKEASLPLPGYKVREIVEKILVVADNNKDGKISFEEFVSLMQELKSKDISKTFRKIINKREGITAIGGTSSISSEGTQHSYSEEEKVAFVNWINKALENDADCSHLLPMNPNDGSLFRSLADGILLCKMINLSEPDTIDERAINKKKLTP-FTVSENLNLALNSASAIGCTVVNIGAQDLKEGKPHLVLGLLWQIIKVGLFADIEISRNEALIALLKEGEELEELMKLSPEELLLRWVNYHLTNAGWR-TISNFSQDIKDSKAYFHLLNQIAPKGDRDGGSAVTIDLSGFNEKNDLKRAGFMLQEADKLGCRQFVTPADVVSGNPKLNLAFVANLFNTYPCLHKPDNNDIDLNLLEGE---SKEERTFRNWMNSLGVNPYINHLYSDLADALVIFQLYEMIR-VPVNWNHVNKPPYPALGGNMKKIENCNYAVELGKNEAKFSLVGIAGQDLNEGNATLTLALVWQLMRRYTLKVLSDL---GEGEKVSDDIIIKWVNQTLKSANKSTSISSFKDKSISTSLPVLDLIDAIAPNAVRPEMIKREHLTDEDKLNNAKYAISVARKIGARIYALPDDLVEVKPKMVMTVFACLMGKGLNRLK---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8C2MPY6-1", "uniprot_id": "A0A8C2MPY6_CRIGR", "id": "A0A8C2MPY6-1", "name": "", "aln": "-------------------------------------MENSTTTISREELEELQEAFNKIDIDNSGYVSDYELQDLFKEASLPLPGYKVREIVEKIFVVADSSKDGKISFEEFVSLMQELKSKDISKTFRKIINKREGITAIGGTSSISSEGTQHSYSDEEKVAFVNWINKALEDDPDCSHLLPMNPSDDSLFKSLADGILLCKMVNLSEPDTIDERAINKKKLTP-FTVSENLNLALNSASAIGCTVVNIGAQDLKEGKPHLVLGLLWQIIKVGLFADIEISRNEALIALLKEGEELEELMKLSPEELLLRWVNYHLTNAGWR-TISNFSQDIKDSKAYFHLLNQIAPKGDRDDEPAIAIDLSGFNEKNDLKRAGFMLQEADKLGCRQFVTPADVVSGNPKLNLAFVANLFNTYPCLHKPDNNDIDMNLLEGE---SKEERTFRNWMNSLGVNPYINHLYSDLADALVIFQLYEMIR-VPVNWSHVNKPPYPALGGNMKKIENCNYAVELGKNEAKFSLVGIAGQDLNEGNATLTLALVWQLMRRYTLNVLSDL---GEGEKVNDDIIIKWVNQTLKSANKNTSISSFKDKSISTSLPVLDLIDAIAPNAVRQEMIKRENLTDEDKLNNAKYAISVARKIGARIYALPDDLVEVKPKMVMTVFACLMGKGLNRIK---------------------------", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q14651-1", "uniprot_id": "PLSI_HUMAN", "id": "Q14651-1", "name": "Plastin-1", "aln": "-------------------------------------MENSTTTISREELEELQEAFNKIDIDNSGYVSDYELQDLFKEASLPLPGYKVREIVEKILSVADSNKDGKISFEEFVSLMQELKSKDISKTFRKIINKREGITAIGGTSTISSEGTQHSYSEEEKVAFVNWINKALENDPDCKHLIPMNPNDDSLFKSLADGILLCKMINLSEPDTIDERAINKKKLTP-FTISENLNLALNSASAIGCTVVNIGASDLKEGKPHLVLGLLWQIIKVGLFADIEISRNEALIALLNEGEELEELMKLSPEELLLRWVNYHLTNAGWH-TISNFSQDIKDSRAYFHLLNQIAPKGG-EDGPAIAIDLSGINETNDLKRAGLMLQEADKLGCKQFVTPADVVSGNPKLNLAFVANLFNTYPCLHKPNNNDIDMNLLEGE---SKEERTFRNWMNSLGVNPYINHLYSDLADALVIFQLYEMIR-VPVNWSHVNKPPYPALGGNMKKIENCNYAVELGKNKAKFSLVGIAGQDLNEGNSTLTLALVWQLMRRYTLNVLSDL---GEGEKVNDEIIIKWVNQTLKSANKKTSISSFKDKSISTSLPVLDLIDAIAPNAVRQEMIRRENLSDEDKLNNAKYAISVARKIGARIYALPDDLVEVKPKMVMTVFACLMGKGLNRIK---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6H742-1", "uniprot_id": "PLSI_BOVIN", "id": "A6H742-1", "name": "Plastin-1", "aln": "-------------------------------------MENSTTTISREELEELQEAFNKIDIDNSGYVSDYELQDLFKEASLPLPGYKVREIVEKILAVADNNKDSRISFEEFVSLMQELKSKDISKTFRKIINKREGITAIGGTSSISSEGTQHSYSEEEKVAFVNWINKALENDPDCKHLIPMNPNDDSLFKSLADGILLCKMINLSEPDTIDERAINKKKLTP-FTISENLNLALNSASAIGCTVVNIGAQDLTEGKPHLVLGLLWQIIKVGLFADIEISRNEALIALLKEGEDLEELMRLSPEELLLQWVNYHLTNAGWP-TISNFSHDIKDSRAYFHLLNQIAPKGDRDDGPAIAIDLTGFSEKNDLKRAEFMLQEADKLGCRQFVTPADVVSGNPKLNLAFVANLFNTYPGLHKPDNNDIDVNLLEGE---SKEERTFRNWMNSLGVNPYINHLYSDLADALVIFQLYEMIR-VPVDWSHVNKPPYPALGGNMKKIENCNYAVELGKNKAKFSLVGIAGQDLNEGNSTLTLALVWQLMRRYTLNVLSDL---GEGEKVNDAIIIEWVNQTLKSANKNTFISSFKDKSISTSLPVLDLIDAIAPNAVRQEMIKREDLSDEDKLNNAKYAISVARKIGARIYALPDDLVEVKPKMVMTVFACLMGKGLNKIK---------------------------", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "P19179-1", "uniprot_id": "PLSI_CHICK", "id": "P19179-1", "name": "Plastin-1", "aln": "-------------------------------------MENNVTTISREELEELREAFNKIDIDNSGYVSDYELQDLFKEASLPLPGYKVREIIEKIFAVTDSNKDGKINFEEFVSLIQELKSKDVSKSYRKSINKKLGITALGGTSSISTEGTQHSYSEEEKVAFVNWINKALQDDPDCKHILPMNPSDASLFKSLADGILLCKMINFSQPDTIDERAINKKKLTP-FTISENLNLALNSASAIGCTVVNIGSQDLQEGKPHLVLGLLWQIIKVGLFADIEISRNEALIALLNEGEELDQLMKLSPEELLLRWVNYHLANAGWQ-KISNFSQDIRDSRAYYHLLNQIAPKGDDFDEIHVEIDFSGFNDKNDLRRAECMLQQADKLGCRQFVTPADVVAGNPKLNLAFVANLFNTYPALHKPDNSSYDLTLLEGE---SNEERTFRNWMNSLGVSPYVNHLYSDLSDALIIFQLYEMTR-VPVDWTHVNKRPYPLLGGNMKKIENCNYAVELGKTKAKFSLVGIAGHDLNEGNPTLTLALIWQLMRRYTLNVLSDL---GEGEKVNDEIIIKWVNQTLANANKKTSITSFKDKSISTSLPVLDLIDAIAPKAVRQEMVKREDLSYQDKLNNAKYAISVARKIGARIYALPDDLVEVKPKMVMTVFACLMGRGLNKIK---------------------------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "A0A8M9QBL9-1", "uniprot_id": "A0A8M9QBL9_DANRE", "id": "A0A8M9QBL9-1", "name": "", "aln": "MALITRGLHRIFLWTKRQNSTITGPFLHGVKCFEETSMENKVTQISREDLEDLREAFNKIDIDNSGYVSDFELQELFREASFHLPGYQIREIVEKFIAG-DTNKDEKISFEEFVAISQELRSKEVRETFRKCISRRDGIRSFGGTSGISSEGTQHSYSDEEKVAFVNWVNKALANDPDCKHLIPMDPGTDSLFKSVKDGILLCKMINLSQPDTIDERVIN-KKCTP-FTMTENLMLALNSASAIGCTVVNIDAQDMKAGTPHLVLGLLWQIIKIGLFADIEISRNEALIALLDESEELDHLMSMSPEDLLLRWVNYHLKAAGWK-QIRNFSEDIKDSRAYFHLLNQISPKGDLDDQMRIDIDMLGLTERDDEMRAELMLRQAARLDCRQFVTPKDVVAGNHKLNMAFVANLFNMYPALNRPTDNGIDY-AIEGE---TREDRTFRNWMNSLGVSPYVNHLYSDLHDGLIILQLYERIQ-IPVDWPRVNKPPYPVLGSNMKKLENCNYAVALGKKEAKFSLVGIGGENINEGSPMHTLALVWQLMRRYTLKVLSDL---GDGEKVSDQIIINWVNSTLKQGDKNSSISSFKDKSISTSLPVIDLIDTIVPKAIKYEMVKSGDMTAEDKLNNAKYAISVARKIGVKVYALPDDLVEVKPKMVMTVFACLMGRGLKKVDG--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O50064-1", "uniprot_id": "FIMB2_ARATH", "id": "O50064-1", "name": "Fimbrin-2", "aln": "---------------------------MSGFVGILVSDPWLQNQFTQVELRSLKSHFTSMKRE-SGKLTVSDLASRMGKSKVVGDQNLSNEERATLIQNFHPNLNDEVDFEFYLRIYLNLQAHVNAIIG-------SGVKNSSAFLKAATTTLLHTISDSEKSSYVAHINNYLSGDEFLNKCLPINPSSNDLFEVAKDGVLLCKLINVAVPGTIDERAINTKSMLNPWERNENHTLCLNSAKAIGCTVVNIGTQDIIEGRRHLVLGVISQIIKIQLLADLNLKKTPQLVELVGDSKDVEELMSLPPEKILLRWMNFQLRKTEYKKTVTNFSSDVKDAEAYTNLLNVLAPEHK---------NPSHLAVKSSFERAKLVLEHADKMGCRRYLTAKDIVEGSPNLNLAFVAHIFQHRNGLSTQTKQISFLENLADDIQISREEKAFRFWINSFDGSVYINNVFEDLRDGWILLQTLDKVSPGIVNWKVSSKPPIKLP---FKKVENCNQVVKLG-KQLKFSLVNIAGNDIVQGNKKLILAYLWQLMRYNILQLLKNLRLHSNGKEITDADILEWANAKVRNNGCKTRMYSFRDKSLSDGVFFLELLSSVQPRSVNWSLVTNG-VTDEEKKMNATYVISIARKLGCSIFLLPEDIIEVNQKMMLTLTASIMYWTLKQPLHLNKPIGSPDSHNGSLLDDSTSDSSIE", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 185, "similar_positions": 235, "identity": "26.32%" }, { "cls_id": "homologset.oma.818319", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q99K51-1", "uniprot_id": "PLST_MOUSE", "id": "Q99K51-1", "name": "Plastin-3", "aln": "---------MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMVDGDRNKDGKISFNEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN-KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQK-INNFSADIK---------DSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEG--ETREERTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIKVP-VDWS-KVNKPPYPKLGANMKKLENCNYAVELGKNPAKFSLVGIGGQDLNDGNPTLTLAVVWQLMRRYTLNVLEDLGE---GQKANDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKRV---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63598-1", "uniprot_id": "PLST_RAT", "id": "Q63598-1", "name": "Plastin-3", "aln": "---------MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMLDGDRNKDGKISFNEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN-KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQK-INNFSADIK---------DSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEG--ETREERTFRNWMNSLGVNPHVNHLYVDLQDALVILQLYERIKVP-VDWS-KVNKPPYPKLGANMKKLENCNYAVELGKNQAKFSLVGIGGQDLNDGNPTLTLAVVWQLMRRYTLNVMEDLGE---GQKATDDIIVNWVNGTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKTGNLTEEDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKSV---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13797-1", "uniprot_id": "PLST_HUMAN", "id": "P13797-1", "name": "Plastin-3", "aln": "---------MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMLDGDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN-KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQK-INNFSADIK---------DSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEG--ETREERTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIKVP-VDWS-KVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGD---GQKANDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKRV---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A7E3Q8-1", "uniprot_id": "PLST_BOVIN", "id": "A7E3Q8-1", "name": "Plastin-3", "aln": "---------MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMLDGDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN-KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQK-INNFSADIK---------DSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEG--ETREERTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIKVP-VDWS-KVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGD---GQKANDDIIVSWVNRTLNEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGTLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKRV---------------------------------------------------------------", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A5K1TXL1-1", "uniprot_id": "A0A5K1TXL1_PIG", "id": "A0A5K1TXL1-1", "name": "Plastin-3", "aln": "-----------------------------MLDGDRNKDGKISFDEFVYVIKEGTVGTR----WITIKTATLP--RN---------HLVIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN-KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQK-INNFSADIK---------DSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEG--ETREERTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIKVP-VDWS-KVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGD---GQKANDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLSEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKRV---------------------------------------------------------------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A1D5PE96-1", "uniprot_id": "A0A1D5PE96_CHICK", "id": "A0A1D5PE96-1", "name": "Plastin-3", "aln": "-----------MAVTMQISKDELEELKEAFAKVDLNSNGFICDYELHELFKEANLPLPGYKVREIIQKLMIDSDKNKDGKISFEEFVYIFQEVKSSDIAKTFRKAINRKEGICAIGGTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN-KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLREGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGENLEDLMKLSPEELLLRWANFHLENAGWHK-INNFSTDIKLTDFGNSVKDSRAYFHLLNQIAPKGQKEGEPQIDINMSGFNEKDDLRRAEYMLQQADRLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEG--ETREERTFRNWMNSLGVNPHVNHLYGDLQDALVILQLYEKIKVP-VDWN-KVNKPPYPKLGANMKKLENCNYAVDLGKHPAKFSLVGIGGQDLNDGNPTLTLALVWQLMRRYTLNVLEDLGD---GQKANDDIIVNWVNQTLKEAGKSTSIQNFKDKTISTSLAVVDLIDAIQPGCINYDLVKTGHLSEDDKQNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKRV---------------------------------------------------------------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q6DG81-1", "uniprot_id": "PLST_DANRE", "id": "Q6DG81-1", "name": "Plastin-3", "aln": "-------------MAGKISKEELEELREAFGKVDLNGNGFICDHELHDLFKEANLPLPGYKVREIIQKLMEEGDKNKDNMISFDEFVSIFQELKSGDIAKSFRKAINRKEGILAIGGTSELSSAGTQHSFSEEERFAFVNWINTALEHDPDCKHKLPMNPNTDALFKAVGDGIVLCKMINLSVPDTIDERTIN-KKKLTPFTIQENLNLALNSASAIGCHVVNIGALDLREGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEDLMKLSPEELLLRWANFHLENAGWSK-INNFSHDIK---------DSRAYFHLLNQIAPKGQKDGESRIDIDMSGFTEKDDLKRAECMLLQADKLGCRQFVTSTDVMSGNPKLNLAFVANLFNKYPALTKPENQDINWGLLEG--ETREERTFRNWMNSLGVNPHVNHLYGDLQDALVILQLYEKIKVP-VDWNNKVNKPPYPKLGANMKKLENCNYAVELGKTKANFSLVGIGGQDLNDGNPTLTLALVWQLMRRYTLNVLENLGD---GQKVNDDVIVSWVNKTLSQAGKSTKISNFKDKEISSSLAVLDLIDAIQPSSINYDLVKRGSLSDGDKLDNAKYAVSMARKIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKRA---------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7G188-1", "uniprot_id": "FIMB1_ARATH", "id": "Q7G188-1", "name": "Fimbrin-1", "aln": "MSGYVGVVVSDPWLQSQFTQVELRTLNSKYVSVK-NQNGKVTIEDLPPLFAKLKALSATFK-EDEIKGMLGELGSDTSTDVSFEEFLKIYLNLLSKAAEKSGGHHKNS-------SSFLKACTTTLLHTIYQSEKGPFVQHINRYLGDDPFLKQFLPLDPHSNQLYELVKDGVLLCKLINVAVPGTIDERAINTKRVLNPWERNENHTLCLNSAKAVGCSVVNIGTQDLAEGRPHLVLGLISQLIKIQVLADLNLKKTPQLVELLEDSDDVEELLRLPPEKVLLKWMNFHLKKGGYKKTVSNFSADLK---------DAQAYAFLLNVLAP---EHCDP------ATLDAKDPLERAELVLSHAERMNCKRYLTAEEIVEGSSTLNLAFVAQIFHERNGLNKDGKYAFAEMMTEDVETCRDERCYRLWINSLGIDSYVNNVFEDVRNGWILLEVLDKVSPSSVNWK-HASKPP---IKMPFRKVENCNQVIKIGK-QLKFSLVNVAGNDIVQGNKKLILGLLWQLMRFHMLQLLKSLRSRTLGKEMTDADILSWANRKVRTMGRKLQIESFKDKSLSSGLFFLNLLWAVEPRVVNWNLVTKG-ETDDEKRLNATYIVSVARKLGCSVFLLPEDIVEVNQKMILILTASIMYWSLQRHSRESSDSSSTQSTTTTCTSTASSPAPSVTEEEEVSSLSGEVTSLAVGDAVSEITTVSEEASIE", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * :* : :: :: : . *: : .: *: :: * *: : * .. : .: *: :.*: .**: ** * .** :: :*::*::: *:: * **::***:**::**.*****:** *: *.*: :** .*.****.*:** *****: ** *:*******: *:*** ::**::*.:. *. **.*.: :*:*::*.**::**:* ****::.*: * :.*** *:* *::** .*** :** :. :. : : .* *.*** :* :*:::.*::::*. :::.*...*******::*:: .*.* : : : *. *:** :* *:****::.:**::: *:::. ::*:: :::. . *:*. :..*** : ::*:**** .:.:** :****.:.*:*: :** .* *.::***** : *::::.* . *:: .* *:.*.* .: *:. .*..**** :*:.* .::*: *::* :*::**. * :: :* **.* **:**::*. *: ****:***: **:: : *.:* .:: ", "identical_positions": 206, "similar_positions": 225, "identity": "28.61%" }, { "cls_id": "homologset.oma.818380", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A4X1SWJ9-1", "uniprot_id": "A0A4X1SWJ9_PIG", "id": "A0A4X1SWJ9-1", "name": "26S proteasome non-ATPase regulatory subunit 12", "aln": "-MADGGSERADGRIVKMEVDYSATVDQRLPECEKLAK----------------------ASDMVSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEIT--DLPVKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEK-----------------------LKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTP------------------------------------------------CIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIPKYKDLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFGYTEEGEKRWKDLKNRVVEHNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKDPNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIHNLQ-----", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q2KJ25-1", "uniprot_id": "PSD12_BOVIN", "id": "Q2KJ25-1", "name": "26S proteasome non-ATPase regulatory subunit 12", "aln": "-MADGGSERADGRIVKMEVDYSATVDQRLPECEKLAKEG--RLQEVIETLLSLEKQTRTASDMVSTSRILVAIVKMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEIT--DLPIKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEK-----------------------LKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTP------------------------------------------------CIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIPKYKDLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFGYTEEGEKRWKDLKNRVVEHNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKDPNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIHNLQ-----", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "O00232-1", "uniprot_id": "PSD12_HUMAN", "id": "O00232-1", "name": "26S proteasome non-ATPase regulatory subunit 12", "aln": "-MADGGSERADGRIVKMEVDYSATVDQRLPECAKLAKEG--RLQEVIETLLSLEKQTRTASDMVSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEIT--DLPIKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEK-----------------------LKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTP------------------------------------------------CIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIPKYKDLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVEHNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKDPNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIHNLQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D8W5-1", "uniprot_id": "PSD12_MOUSE", "id": "Q9D8W5-1", "name": "26S proteasome non-ATPase regulatory subunit 12", "aln": "-MADGGSERADGRIVKMEVDYSATVDQRLPECEKLAKEG--RLQEVIETLLSLEKQTRTASDMVSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEIT--DLPVKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEN-----------------------LKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTP------------------------------------------------CIQAESDKWQQALKSVVLYVILAPFDNEQSDLVHRISSDKKLEEIPKYKDLLKLFTTMELMRWSTLVEDYGVELRKGSSETPATDVFSSTEEGEKRWKDLKSRVVEHNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGVINFQRPKDPNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIHNLQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1NPQ0-1", "uniprot_id": "F1NPQ0_CHICK", "id": "F1NPQ0-1", "name": "26S proteasome non-ATPase regulatory subunit 12", "aln": "-MAEGGAERADGRIVKMEVDYSATVDQRLPECERLAQEG--RLQEVIENLLSLEKQTRTASDMVSTSRILVAIVKMCYEAKDWDALNENIILLSKRRSQLKQAVAKMVQQCCTYVEDIT--DLPVKLRLIDTLRTVTEGKIYVEIERARLTKTLATIKEQNGEVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEK-----------------------LKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTP------------------------------------------------CIQAESEKWQQALKSVVLYVILSPYDNEQSDLVHRISSDKKLEEIPKYKDLLKLFTTMELMRWTALVEEYGKELREGSLDSPATDVFGCTEEGEKRWKDLKNRVVEHNIRIMAKYYTRITMKRMAQLLDLSVDESEEFLSNLVVNKTIFAKVDRLAGIINFQRPKDPNNILNDWSHKLNSLMALVNKTTHLIAKEEMIHNLQ-----", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9V3Z4-1", "uniprot_id": "Q9V3Z4_DROME", "id": "Q9V3Z4-1", "name": "", "aln": "-MDTYLFD--GGRITKMEVDYEPACNEKIPLAKELAKKNPDAFHEAIEMMLQLEKQTRLGADMVSCSRVLVAICQICFDASNWNALNEYVSLLVRRRSQLKQAVVKMIQECVTYVDKTP--DKETKLKLIDTLRSVTEGKIYVEIERARLTKILADIKEADGDVAGAATVMEELQVETYGSMDKREKVELILEQMRLCLLKEDYVSTQIIAKKISIKFFDDPAQHD-----------------------LKLKFYYLMIQLNRDT-SFLNTSRHYQAIAEPPRKKTGLTPVDSAASTDEQKKKDDDKKKKEEDDKDKKPEVATEAEVEIELTEEQKKELTEKLVCAVLYCVLAPFDNEQSDMMAHLSKNKKLEEVPAYKEILRLFMSKELINFDTFNADFGLVLAENEMFK------DSTKHGKKCITELKDRLIEHNIRIIAMYYSRLHLARMSELLNLPTSRCEEYLSKLANTDTIRVKIDRPAGIIYFTQKKSASDILNNWATDVNQLMSLVNKTCHLINKEECVYSVMCAVED", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q54UJ0-1", "uniprot_id": "PSD12_DICDI", "id": "Q54UJ0-1", "name": "26S proteasome non-ATPase regulatory subunit 12", "aln": "MTIGLEPAVSSKTKDKMEQDLSPIADKSCKENRELAKSG--KLIEAIENLLITEKQCRQAEDSPSTSKIAAEIIKLCYEAGRLDLVNEKLVLLSKRRGQLRPAIKAIVQESMVYVDQIT--DMKQKLELIDTLRTISDGKIFVENERARLTKTLSKIKEDEGDIASAAKILQDLQVETYGTMEKREKITFFIDQMRICMNNKDFIRAQLIGNKVNRKTLAEDENQD-----------------------LKIDYFKQMIRYFSHSANYIEIARCYLSIYDTP------------------------------------------------SVEKDTPQLLQTLKYICIYVILSASSNEQSDLLNRVYEFKPLTDIQNYKDLLNQFKTLELIRWSTFFELNKPELDSQTVFKT----------EPNAWEDLRKRVIEHNIRVISTYYQKISTARLAELLDLSLDESEKFVSDLVSNKTIFAKIDRPAGIATFTTTNDPNKVLNAWANNITSLLDLVEKTNHLVQREFMLHKIN-----", "tax_id": 44689, "tax_name": "Social amoeba" }, { "uniprot_ac": "Q9FIB6-1", "uniprot_id": "PS12A_ARATH", "id": "Q9FIB6-1", "name": "26S proteasome non-ATPase regulatory subunit 12 homolog A", "aln": "----------------------------------MGDSG--KLEATIDRLLNEEKQMRLAENVAGTRKAATEILQLCFDAKDWKLLNEQILNLSKKRGQLKQAVQSMVQQAMQYIDQTP--DIETRIELIKTLNNVSAGKIYVEIERARLTKKLAKIKEEQGQIAEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDFVRAQILSRKINPRVFDADTKKDKKKPKEGDNMVEEAPADIPTLLELKRIYYELMIRYYSHNNEYIEICRSYKAIYDIP------------------------------------------------SVKETPEQWIPVLRKICWFLVLAPHDPMQSSLLNATLEDKNLSEIPDFKMLLKQVVTMEVIQWTSLWNKYKDEFEKEKSMIGG-------SLGDKAGEDLKLRIIEHNILVVSKYYARITLKRLAELLCLSMEEAEKHLSEMVVSKALIAKIDRPSGIVCFQIAKDSNEILNSWAGNLEKLLDLVEKSCHQIHKETMVHKAALRP--", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q12250-1", "uniprot_id": "RPN5_YEAST", "id": "Q12250-1", "name": "26S proteasome regulatory subunit RPN5", "aln": "--------MSRDAPIKADKDYSQILKEEFPKIDSLAQND---CNSALDQLLVLEKKTRQASDLASSKEVLAKIVDLLASRNKWDDLNEQLTLLSKKHGQLKLSIQYMIQKVMEYLKSSKSLDLNTRISVIETIRVVTENKIFVEVERARVTKDLVEIKKEEGKIDEAADILCELQVETYGSMEMSEKIQFILEQMELSILKGDYSQATVLSRKILKKTFKNPKYES-----------------------LKLEYYNLLVKISLHKREYLEVAQYLQEIYQTD------------------------------------------------AIKSDEAKWKPVLSHIVYFLVLSPYGNLQNDLIHKIQNDNNLKKLESQESLVKLFTTNELMRWPIVQKTYEPVLNEDDLAFGG-------EANKHHWEDLQKRVIEHNLRVISEYYSRITLLRLNELLDLTESQTETYISDLVNQGIIYAKVNRPAKIVNFEKPKNSSQLLNEWSHNVDELLEHIETIGHLITKEEIMHGLQAK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. . : . . . : .: . . :** : * :::.**: :: ::*: *:.. * :: :*.*:. :: .**:** ****:** * **: :*.: ** :: :: ***:*:* *:: ::::*:.:.: *: : ::..*: : : .. ** :: ::: . .::. .: * : : : * : :*:. . *..:: : * .: : ::. . : *::.: . : . : :*: *::***: ::: ** :: *: :** *. .. * .:*.:. : .*::* : : * :....:** *: .: .*: ::. * : :* :: ", "identical_positions": 65, "similar_positions": 156, "identity": "12.1%" }, { "cls_id": "homologset.oma.818558", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GIH3-1", "uniprot_id": "A0A8I6GIH3_RAT", "id": "A0A8I6GIH3-1", "name": "", "aln": "---------------------------MAAAMPLG--LSLLLLVLVGQGCCGRVEGPRDS------------LREELVITPLPSGDVAATFQFRTRWD------SDLQREGVSHYRLFPKALGQLISKYSLRELHLSFTQGFWRTRYWGPP----FLQAPSGAELWVWFQDT---VTDVDKSWKELSNVLSGIFCASLNFIDST--NTVTPTASFKPLGLANDTDHY----------------------------------FLRYAVLPREVVCTENLTPWKKLLPCSSKAGLSVLLKADRLFHTSYHSQAVHIRPICRNAH----------CTSISWELRQTLSVVFDAFITGQGKKDWS-----LFRMFSRTLTEACPLASQSLVYVDITGYSQDNETLEVSPPPTSTYQDVILGTR--------KTYAVYD-LFDTAMINNSRNLNIQLKWKRPPDN----EALPVPFLHAQRYVSGYGLQKGELSTLLYNSHPYRAFPVLLLDAVPWYLRLYVHTLTITSKGKDNKPIGQTPQILHTDGLVESLFPIETSQAISTICIALNILILQAPTEQLSYIHYQPAQDRQQPHLLEMLIQLPANSVTKVSIQFERALLKWTEYTPDPNHGFYVSPSVLSALVP--------------SMVAAKPVDWEESPLFNTLFPVSDGSSYFVRLYTEPLLVNLPTPDFSMPYNVICLTCTVVAVCYGSFYNLLTRTFHIEEPKSG--GLAKRLANLIRR-----------ARGVPPL--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BXQ2-1", "uniprot_id": "PIGT_MOUSE", "id": "Q8BXQ2-1", "name": "GPI-anchor transamidase component PIGT", "aln": "---------------------------MAAAMPLGLPLRLLVLLLVGRGCCGCAEGPRDS------------LREELVITPLPSGDVAATFQFRTRWD------SDLQREGVSHYRLFPKALGQLISKYSLRELHLSFTQGFWRTRYWGPP----FLQAPSGAELWVWFQDT---VTDVDKSWRELSNVLSGIFCASLNFIDAT--NTVTPTASFKPLGLANDTDDY----------------------------------FLRYAVLPREVVCTENLTPWKKLLPCSSKAGLSVLLKADRLFHTSYHSQAVHIRPICRNAH----------CTSISWELRQTLSVVFDAFITGQGKKDWS-----LFRMFSRTLTEACPLASQSLVYVDITGYSQDNETLEVSPPPTSTYQDVILGTR--------KTYAVYD-LFDTAMINNSRNLNIQLKWKRPPDN----EALPVPFLHAQRYVSGYGLQKGELSTLLYNSHPYRAFPVLLLDVVPWYLRLYVHTLTITSKGKENKP---------------------------------------------SYIHYQPAQDRQQPHLLEMLIQLPANSVTKVSIQFERALLKWTEYTPDPNHGFYVSPSVLSALVP--------------SVVAAKPVDWEGSPLFNTLFPVSDGSSYFVRLYTEPLLVNLPTPDFSMPYNVICLTCTVVAVCYGSFYNLLTRTFHIEEPKSG--GLAKRLANLIRR-----------ARGVPPL--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969N2-1", "uniprot_id": "PIGT_HUMAN", "id": "Q969N2-1", "name": "GPI-anchor transamidase component PIGT", "aln": "-------------------------------MAAAMPLALLVLLLLGPGGWCLAEPPRDS------------LREELVITPLPSGDVAATFQFRTRWD------SELQREGVSHYRLFPKALGQLISKYSLRELHLSFTQGFWRTRYWGPP----FLQAPSGAELWVWFQDT---VTDVDKSWKELSNVLSGIFCASLNFIDST--NTVTPTASFKPLGLANDTDHY----------------------------------FLRYAVLPREVVCTENLTPWKKLLPCSSKAGLSVLLKADRLFHTSYHSQAVHIRPVCRNAR----------CTSISWELRQTLSVVFDAFITGQGKKDWS-----LFRMFSRTLTEPCPLASESRVYVDITTYNQDNETLEVHPPPTTTYQDVILGTR--------KTYAIYD-LLDTAMINNSRNLNIQLKWKRPPEN----EAPPVPFLHAQRYVSGYGLQKGELSTLLYNTHPYRAFPVLLLDTVPWYLRLYVHTLTITSKGKENKP---------------------------------------------SYIHYQPAQDRLQPHLLEMLIQLPANSVTKVSIQFERALLKWTEYTPDPNHGFYVSPSVLSALVP--------------SMVAAKPVDWEESPLFNSLFPVSDGSNYFVRLYTEPLLVNLPTPDFSMPYNVICLTCTVVAVCYGSFYNLLTRTFHIEEPRTG--GLAKRLANLIRR-----------ARGVPPL--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1SD35-1", "uniprot_id": "F1SD35_PIG", "id": "F1SD35-1", "name": "", "aln": "MAPEVTSPTLFLLEAGHPRGRDYWEAEAAAGMAAAVPLFLSVLLLLGPGSWSQAESPRDS------------LREELVITPLPSGDVAATFQFRTRWD------LDLQREEVSHYRLFPKALGQLISKYSLRELHLSLTQGFWRTRYWGTP----FIQAPSGAELWVWFQDT---VTDVDKSWKELSNVLSGIFCASLNFIDST--NTVTPTASFKPLGLANGTDHS----------------------------------FLRYAVLPREVVCTENLTPWKKLLPCSSKAGLSVLLKADRLFHTSYHSQAVHMRPVCRNAR----------CTSVSWELRQTLSVVFDAFVTGQGKKDWS-----LFRMFSRTLTEPCPLAAESRVYVDITSYSQDNETLEVYPLPLTTYQDVILGTR--------RTYAVYD-LLDSAVINNSRSLNLQLKWKRPPEN----EAPPVPFLHAQRYVSGYGLQNGELSTLLYNTHPYRAFPVLLLDTVPWYLRLYVHTLTITSKGKENKP---------------------------------------------SYIHYQPARDRLQPHLLEMLIQLPANSVTKVSIHFERALLKWTEYTPDPNHGFYVSPSVLSALVP--------------SVVAAKPVDWDESPLFNTLFPVSDGSSHFVRLYTEPLLVNLPTPDFSMPYNVICLTCTVVAVCYGSFYNLLTRTFHIEEPRTG--GLAKRLANLIRR-----------ARGVPPL--------------------------------------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "F1P2G6-1", "uniprot_id": "F1P2G6_CHICK", "id": "F1P2G6-1", "name": "", "aln": "--------------------------------MLAVGLVLLLAAGLGQG------TTRGV------------LREELLLRPLPVGDVAAVFQFRTRWD------ADLQQGAVSHYRLFPKALGQLVAAHGVRELHLALTQGFWSTQSWGQP----PLGAPAGAELWVWFQDT---VPDVDKAWKELSNILSGIFCASLNFIDST--NTVTPTASFKPLGVANGTDHR----------------------------------LLRYAVLPREVVCTENLTPWKKLLPCGSKAGLAVLLKAERLFHSSYHSQAVHIRPICRDAS----------CLAVSWELRQTLTVVFDSFTSGQGKKDWS-----LFKMFSRTLTDACPLASESKVYVDISPKNKEKQLLEVTPTPTSVHEAIVQGDK--------TTYAVYD-LLSPVLFNTSRSLNVQLKWKRPEDS----SELSTPIMHAQRYVSGYGLQTGEISTLIYNTHPYRAFPVILLETVPWYLRLYVHTLTIITKGKENKP---------------------------------------------SYMHYQPAQDRKRPHLLEMLIQLPANSATKITIQFERALLKWTEYPPDPNHGFYVSSSVLSALVP--------------SVIAMKDVNVEESPLFTSLFPSSDGSSYFLRLYTEPLLVNLPTPDFSMPYNVICLTCTVVAVCYGSFYNLLTRTFHVEEPSRG--GLAKRLANVIRR-----------LRGVPPI--------------------------------------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9W3G0-1", "uniprot_id": "Q9W3G0_DROME", "id": "Q9W3G0-1", "name": "", "aln": "----------------------------------MYPVAFVLLLLVAPNADANLGRDDER------------FHEELVVRPLSGDHVNTYFQFTTRWH------YGE-KDNLYHTQLTPRVIAELLQQFAVKELHIGLTQGLWRYETWGYP----IVEATSGAEMWAWFSGANLTNRDVDRQWKELANVFSGVLCASLNFVDNT--NSIAPRHLIRPQFMP-ANGQR----------------------------------FVRYATLPREIVCTENLTPWKKLLPCGSASGFASLLNSGHVHNTKYHSLGLKVRVLCEDHD----------EDNCIVELTQTANLVYDLRLFELSNNDFS-----LRRLFGMGLNGYCELAESSKIYVQR---NELGERYQLVPEPVHEVKTTRGGHS--------VVYSVYD-MHEQFKEAGERLFNVAWLAPKSANRRRNLAKPSLPPVTVHRYLLGHGQERGRIVTEVTNSH-YDALPIMLQEVIPWYVHAYLHTLSIRRKPQRVNEYG-------------------------------------GQRLTFKLLHYTPGKQRELPSHLEIGFMLPGQTSALISIDVDYLLLKWLEYPPDANHGHYIGSAIVSSQLP--------------MGRNYTALPPE-GHLFEHSFNATR-PSYVLSLHTEALIVSLPTPDFSMPYNVICLACTVVALAFGPIHSVATKMIIVGRQTSAPKNFVKKIFNQLFRRGKATDETAAEGEGLPAAGAAATGVASGRAAISPGSPSGDQPLLEDLDEEEEEEQD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B0G182-1", "uniprot_id": "B0G182_DICDI", "id": "B0G182-1", "name": "GPI transamidase component PIG-T homolog", "aln": "------------------------------MGLKFLVVILILSIFVNSNEATKTTKNDDDNSSYATFNETQSFFEELLIKPLPKGKLMTHVQFTTEWNS-----NFLEKSTFQHYDLFPRSIGDLITRVGIEEFTLVFTQGRWSYSEWGYP----VRAAPVGVELIAWMKPL---EKGIDAQWRELTHSLSGLFCASMQFLYQVPHHTSSPNRSFRPEGESNIYNYNGGDEDSFSSSSSSSSTTTTTTPAIKLNNGTIVPLELRYGILPRESVCTENLTPWVKLLPCREQSGLGKLLNPHKLYDVHYHSMSITIRKICKNNNNNNNTDNDSSCLSPTLEIVQSLTIVNDLNNNQHQQETIETNLDNLFGLKGNTGLSACPLASRSKIYIQKQPSLNTNLKITNIGANSNNIEQQQQQQQSDSFKNGEKETDNFY-IYDLMKYSTNKPLKLKMNWSKNFKR------KFETPVVAHSHLTGYGQERGGIATQIFNTENYAIN-ITYFQAIPWYLRLYFHTLKFNIETSGEKSIDN--------------------------------TNRKEDSPFLLYKNISPAETRSSPSTIELSFEMPPNSVASMSIEFDKVFLHYTEHPPDANRGFDLGSGVVTAFIKSSNANEGDAIHLEWSNETYNNNNNNNNNNNNNNRNNDKSSIIPVRIYTEGLLITLPTPDFSMLYNVITLTGTVFALFFGSMINILIRRFKNTFTGND--FVSDRPIAKIYR------------RILRFIDGK-----------------------------------", "tax_id": 44689, "tax_name": "Social amoeba" }, { "uniprot_ac": "P38875-1", "uniprot_id": "GPI16_YEAST", "id": "P38875-1", "name": "GPI transamidase component GPI16", "aln": "----------------------------MILTLAYFMLGTLLLGVFAEDTVSQIGINDSLWYP---------YDEALVLKPLPNNDLLLSFAFQLQSEPFDPAVSSMSYDAYEHYTTFPRAIPPLLESTATRQFHLRFTRGFWDALSWGQLPHAGKEAGASGVELWSQVQAMD--QEQAFHNWKKLSNSLSGLFCSSLNFIDES--RTTFPRRSYASDIGAPLFNST-------------------------------EKLYLMRASLPNEPICTENLTPFIKLLPTRGKSGLTSLLDGHKLFDSLWNSISLDIATICSEDEDALCHYEMDARIEMVTHVPSALARGERPIPKPLDGNTLR---CDTDKPFDSYQCFPLPEPSQTHFKLSQLFARPINNGNLFANRPTRICAEVDRSTWTAFLSVDDTIFSTHDNCFDLSNDQNEGGSGYDFILESTDTT--KVTPIVPVPIHVSRSLTGNGQDRGGMR-IVFHNDNDTPVKLIYFESLPWFMRVYLSSLQITSTTSPQLQEND----------------------------------------IILDKYYLQAADRKRPGHLEFTMLIPANTDIVMTYQFDKALLQFAEYPPDANHGFEIDAAVITVLSLE-------------------------------------SSSSLYEMRTSTLLLSLSTPDFSMPYNVIILTSTIMGLIFGMLYNLMVKRMVTVEEADKITLQSGLKYKLLKLK----------EKFLGKKKTKTD---------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . * *:: **. ..: . * . . * *: : *: . .:: : :*:* * ** .. *.*: .. *::*:: :**::*:*::*: .: * . . . : . **.* :*******: **** :*: **. ::.. ::* .: : :* : .: .: : . . : . :. . . . : . : * * : * : : :.. : : :**::: *. :* : . . * * :*: : :* :: :: ..: :*:: *:.**.*:*. :...::: . : *. *::.*.****** **** *: *:..: :* : .: : : : . : ", "identical_positions": 75, "similar_positions": 145, "identity": "9.28%" }, { "cls_id": "homologset.oma.818779", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1LUU6-1", "uniprot_id": "F1LUU6_RAT", "id": "F1LUU6-1", "name": "Rho guanine nucleotide exchange factor 38", "aln": "MEPREAAGKETMGSKRKNLTFLRSRLYMLERRKTDTVVDSSVSGDHSGSLRRSQSDRTEYNQKLQEKMTPQAECSSAETPTPEEEQQVGRMMAKRAKIIRELIQTERDYLTDLELCVREVVQPLRSKQIDRLDVESLFSNIESVHQISAKLLSLLEEATTDVEPAVQVIGEVFLQIKGPLEDVYKIYCYHHDEAHSVLESYEKEEDLKQHLSHCIQSLKTIYMQEGKPNLLDMGSLMIKPIQRVMKYPLLLCELRNSTPPSHPDYRALEEAFAAVKDINVNINELKRRKDLVLKYKKNEEEESLKDKLSRLNIHSISKKSKRVTNHLKILTRGDSQVKDNTFNREEKLFRSLEKTVRLCVKNISSCLQHIEEAVPFTLHSVAALCEISYK-DGEKN-CMEPQSQASNPCHDFAARSQRLILSPLSTLLSLFPGPQKLIQKRYDKLLDCNSSLPRSATTESDLAKREYEALNAQLVEELQAFNQAARKILLNCLLSFVTLLRDLMLVALQAYS-TVKTVPLPVLGISEIQNQVLEEVHSLNFVKDNS-ATFIERKLSFEKKKPTQVLPEVPHQTDVHRSKLLSTYGAEELYRAKRKCNATQEHDVSLLEGELVAVLEQKDPLGSTSRWFVDTGFVKGYVYSSFLRPYNPGKEQKVDAENRFCDDDFENISLFVSCRPAGDSVS------ISDSSSSLSGSCGKFETNGADADNFQEVDEQ-VFYAVHAFQARSDHELSLQEYQRVHILRFCDLSGNKEWWLAETQGQKGYVPANYLGRMTYA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80VK6-3", "uniprot_id": "ARH38_MOUSE", "id": "Q80VK6-3", "name": "Rho guanine nucleotide exchange factor 38", "aln": "MEPREAAGKETMGSKKKNLTFLRSRLYMLERRKTDTVVDSSVSGDHSGSLRRSQSDRTEYNQKLQEKMTPQAECSSAETPTPEDEQQVGRMMAKRAKIIRELIQTERDYLTDLELCLREVVQPLRSKQIDRLDVEGLFSNIESVHQISAKLLSLLEEATTDVEPAMQVIGEVFLQIKGPLEDIYKIYCYHHDEAHSVLESYEKEEELKQHLSHCLQSLKNIYLQEGKPNLLDMGSLMIKPIQRVMKYPLLLCELRNSTPPSHPDYRALGEAFAAVKDINVNINELKRRKDLVLKYKKNEEEESLKDKLSKLNIHSISKKSKRVTNHLKILTRGESQVKDNTFNREEKLFRSLEKTVRLCVKNISSCLQHIEEATPFTLQSGAELREISYQ-DGEKN-GTEPQDQASKPYQDFAARSQRLILNPLSALLSLFPGPQKLIQKRYDKLLDYNSSLPRSATTESDLAKREYEALNAQLVEELQAFNQAAKTILLNCLCSFVTLLRDLMQVALQAYS-TVKTVPLPVLGISEIQSRVLEEVHSLTFVKENS-ATFIERKLSFEKKKPAQILPEVPHQTDAHRSKLLSTYGAEELYRAKRKCNATQEHDINLLEGELVAVLEQKDPLGSTSRWFVDTGCVKGYVYSSFLKPHNPGKGQKVDADNRFCDDDFENISLFVSCRPAGDRVS------ISDSSSSLSGSCGKFETNGADADNFQEVDEQ-IFYAVHAFQARSDHELSLQEYQRVHILRFCDLSGNKEWWLAEAQGQKGYVPANYLGKMTYA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NXL2-2", "uniprot_id": "ARH38_HUMAN", "id": "Q9NXL2-2", "name": "Rho guanine nucleotide exchange factor 38", "aln": "MEPKEATGKENMVTKKKNLAFLRSRLYMLERRKTDTVVESSVSGDHSGTLRRSQSDRTEYNQKLQEKMTPQGECSVAETLTPEEEHHMKRMMAKREKIIKELIQTEKDYLNDLELCVREVVQPLRNKKTDRLDVDSLFSNIESVHQISAKLLSLLEEATTDVEPAMQVIGEVFLQIKGPLEDIYKIYCYHHDEAHSILESYEKEEELKEHLSHCIQSLKKIYMQEGKPNLLDMGSLMIKPIQRVMKYPLLLCELRNSTPPSHPDYRALDDAFAAVKDINVNINELKRRKDLVLKYKKNDEDESLKDKLSKLNIHSISKKSKRVTNHLKILTRGESQVKDNTFNREEKLFRALEKTVRLCVKNISLCLQHIQDAMPLALQSVMDLQEISYNKDDEMD-YSETLSNALNSCHDFASHLQRLILTPLSALLSLFPGPHKLIQKRYDKLLDCNSYLQRSTGEESDLAKKEYEALNAQLVEELQAFNQAARKILLNCLCSFITLLRDLMLVAQQAYS-TLVPMPLLVSSISEIQNQVLEEIQNLNCVKENS-ATFIERKLSFEKKKPVQILPEMPHQTDIHRSKLLSTYSAEELYQAKRKCNATQEYDINLLEGDLVAVIEQKDPLGSTSRWLVDTGNVKGYVYSSFLKPYNPAKMQKVDAENRFCDDDFENISLFVSSRPASDSVTGTSESSIGDSSSSLSGTCGKFETNGTDVDSFQEVDEQ-IFYAVHAFQARSDHELSLQEYQRVHILRFCDLSGNKEWWLAEAQGQKGYVPANYLGKMTYA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I3LG01-1", "uniprot_id": "I3LG01_PIG", "id": "I3LG01-1", "name": "Rho guanine nucleotide exchange factor 38", "aln": "MEPKEAPGKENMGTRKKNLPFLRSRLYMLERRKTDTAVESSVPGDHSGTLRRSQSDRTEYNQKLQEKMTPQAGCSPVETLTQEEEQQMQRMMAKRSKIIKELIQTERDYLNDLELCVKEVIQPLRNKQIDRLDVDSLFSNIESVHQISAKLLSLLEEATTDVEPAMQVIGEVFLQIKGPLEDIYKIYCYQHDEAHSVLESYEKEEELKQHLSLCIQSLKKIYMQEGKPNLLDMGSLMIKPIQRVMKYPLLLCELRNSTPPSHPDFKALEDAFAAVKDINININELKRRKDLVLKYKKNDEDESLKDKLSKLNIHSISKKSKRVTNHLKILTRGESQVKDSTFNREEKLFRSLEKTVRHCVKNISFCLQHVQDAMSLTLRSVTELQEISHNKDEEERGYSEVSSNAPNLSDDFAAHLQKLVLTPLSALLSLFPGPQKLIQKRYDKLLDYNSYLQRAVADDSDLAKREYEALNAQLVEELHVFNQAARKILLNCLCSFITLLRDLMLLAQRHYS-TVMLVPLSASSISEIQNRVLEEVQSLNFVKDNS-ATFIERKLSFEKKKPVQTVPEVPRQTDTHRSKLLSTYSMEELYQAKRKCNATQEYDINLLEGELVAVMEQKDPLGSSSRWLVDTGLIKGYVYSSFLKPYNPAKVQKVDAENRFCDDDFDNISLFVSSRPAHDSVTGTPEGSISDSSSSLSGTCGKSEANGTDADSFQEVDEQ-IFYAVHAFQARSDHELSLKEYQRVHILRFCDLSGNKEWWLAEVQGQKGYVPANYLGKMTYA", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A8V0XS08-1", "uniprot_id": "A0A8V0XS08_CHICK", "id": "A0A8V0XS08-1", "name": "Rho guanine nucleotide exchange factor 38", "aln": "-----MASTDGVGGRRKNLALLRHRLYMGERRRTEPVVESSGAGEH-GALRRSQSDRTEYGQKLQEKMAPQSGSTSSATLPREDEETTKRMMAKRVKIIAELMHTERDYISDLDLCIKEVIQPLRNKQIAHFDVDGLFSNIESVHQISAKLLSLLEEATTDVEPPMQLIGEVFLQIKGPLEDTYKIYCYRHDDAHTMLESYEKDEELKQHLRHCVQSLKKMYEEEGKPNLMDMGSLMIKPVQRVMKYPLLLCELLNSTPVSHPDHKALQEALSTMKNINVNINELKRRKDLVLKYKRNDDDETLKEKFSRLNIHSISKKSKRVTSHLKILTGGEPQVKDQTFDKEEKLFRSLEKTVKSCVKNISLSSQHLQDSIHLAAQNITGLQEILQNEDDEANKHAKKMNNPTNLCEDLMAQLDKVVLTPLSALQALFSGPQKLIQKRYDKLLDYNSYLQRSTGEELDLAKKDYEALNAQLVEELQVFNTAAKKIVLNCLYFFITLLRNIMSAALQSISAAVVPVPLSSSSICEVQHQLMEEVHKLNFVKENSSATFIERKLSLEKKKPVPSPLESPRQTEDHRSKLLSTYSAELLYQAKRKCNATQEFDIDLHEGEVVAVVEQKDPFQSTSRWLVDTGILKGYVYSSFLKPFNPAKAQKDVAENNFCGDDFD-ISLFVSSRPSSDSSS-SSGHKKSDSDSSLH-SCENPTTNGTGAGGSQDMDDQHTFYAVHAFQARSDQELSLQEYQKVRILRFSDLSGNKEWWLAEAKGQKGYVPSNYLGKMTYA", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ...: : ::***.:** **** ***:*:..*:** .*:* *:***********.*******:**. .: * . *:*. ****** *** **::**:**:.**:**::**:****.*: ::**:.****************************.:*:************** ******:**:**::******:*:**:** *:****.:* :******:*********:************* **** ****.:** :*::::*:**:****************:*:::*:**:*:*:**************.****** *:.****.**::******:*****: ****** . **:::: :: :. * ** : * * : .:. : .*: :: ::::*.***:* :**.**:************ ** * *:. : ****::************:.** **:.*:**** *:****::* * : * :: :** .*.*:* :::**::.*. **:** *********:*****. * *:**: *********. * **:**********.*:.* **::***:*****: *:***:**** :*********:*.**.* ** *:*.**.***: ******.**: * : .**.*** :* : :**:.... *::*:* ************:****:***:*:****.************.:*******:****:****", "identical_positions": 479, "similar_positions": 185, "identity": "61.33%" }, { "cls_id": "homologset.oma.818780", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0AAA9TUG8-1", "uniprot_id": "A0AAA9TUG8_BOVIN", "id": "A0AAA9TUG8-1", "name": "Dynamin-binding protein", "aln": "MEAGSVVRAIFDFCPSVSEELPLFVGDIIEVLAVVDEFWLLGKKEDVTGQFPSSFVEVVTIPSLKEGERLYVCICEFTSLELNSLPLHRGDLVILDG-TLTGGWLQGRNCWGARGFFPSSCVRELCLSSQSRQWHSQSALLQIPEYSMGQARALMGLSAQLDEELDFREGDVITIIGIPEPGWFEGELDGRRGIFPEGFVELLGPLRTVDESVSSGNCDDCISNGEVDTSTGEE-KEPEEDSEQPGTYGIALYRFQALEPNELDFEVGDKIRILGTLEDGWLEGSLKGRTGIFPYRFVKLCPQTRVEETMDLSQESDLTNIPDTPLDCSENSLEAEGKRHEFHEYKPEKSNCVISETPTSTLEHLTSECEENKQSHWDTDPSGGPPGSPGAGHEQLLVKCSSTTDPSEVVNGVASQPPVPFH-PDLQRNQYYSMRGGSHPSPDQYSDSIPLEARTRDYSSLPPRRTSYSQPKTLQKPGPPLHSASSLIASRAVRPSQLSSQLHGLARCVKKHCTPKESASSFCSAPDRSETKPGLQDRAPALEAMTRSQGDGSTDLDSKLTQQLIEFEKSLSGPFPEPDKILRHFSIMDFNSEKDIFRGSSKLMTQQELPERRKALRPPPPRPCTPSSTPPHVPGDQNLRLDPPLAMRPSRPAPLPPSAQQRTNAVPPKLLTCNRPGWESLEKEGPENVDKTLDQTSQCPLVLVRIQEMEQDLDMCRRAQEELNLLLEEKQEESLRAETLQNLEFYENNIESLNMELQQLREMTLLSSQSSSLMAPSGSVSTENPEQRMLEKRAKVIEELLQTERDYIRDLEMCIERIMFPLQQAQIPNIDFEGLFGNMQMVIKVSKQLLTDLEISDNI----------GPVFLDHRDELEGTYKVYCQNHDEAISLLEIYEKDEKIQKHLQDSLADLKSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMELLNSTPESHPDKVPLTSAVLAVKEINVNINEYKRRKDLVLKYRKGDEDSLMEKISKLNIHSIIKKSNRVSSHLKHLTGFAPQIKDEVFEETEKNFRMQERLIKSFIRDLSLYLQHIRESACVKVVAAVSMWDVCMEKGHRDLEQFEKVHRYISDQLFTNFKERTERLVISPLNQLLSMFTGPHKLVQKRFDKLLDFYNCTERAEKLKDKKTLEELQSARNNYEALNAQLLDELPKFHQYAQGLFSNCVHGYAEAHCDFVRQALEQLKPLLSLLKVTGREGNLIAIFHEEHSRVLQQLQVFTFFPESLPTTKRPFERKTMDRQSTRKPFLGMPSYMLQSEELRASLLARYPPEKLFQAERNFNAAQDLDVSLLEGDLVGVIKKKDPMGSQNRWLIDNGVTKGFVYSSFLKPYNARRSHSDASVGSHSSTESEHGSSSPRFPQRQNSGGTLTFNPSSMAVSFSSGPCQKQPPDASSQTEFDQGTLSASLNS---EGSPSRCPSDPDSPSQHRPWDSGD-AVRDLHQPAPTLRNS-RNPRHPEMAGSSVSGRNGQSRDLVKAGARTALFLDDRHEQPESSEAEGNQVYFAVYTFKARNPNELSVSANQRLKILEFKDVTGNTEWWLAEVNGKKGYVPSNYIRKAEYT", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A287A8W6-1", "uniprot_id": "A0A287A8W6_PIG", "id": "A0A287A8W6-1", "name": "Dynamin-binding protein", "aln": "MEAGSVVRAIFDFCPSVSEELPLFVGDIIEVLAVVDEFWLLGKKEDVTGQFPSSFVEVVTIPSLKEGERLFVCISEFTSLELNSLPLHRGDLVILDG-PPTSGWLQGRSCWGARGFFPSSCVRELCLSSQSRQWHSQSALLQIPEYSMGQARALMGLSAQLDEELDFREGDVITIIGVPEPGWFEGELEGRRGIFPEGFVELLGPLRTVDESVSPGNCDDRISNGEADTPVGEEERELEEDSQQPGTYGIALYRFQALEPNELDFEVGDKIRILGTLEDGWLEGSLKGRTGIFPYRFVKLCPQTGAEESVDLPQDSSLTKIPDTSLDLSENSFEAEEEKHESHEYDVEKSNCVISETPMSPLEHLTSEYEEDKNSHWDAGTMGGPPRSPGMGPEQPLARDASTPEPSEVINGVASQPPVSFHHPQLQKSQDYSTAGGSYPSPDQYSDPLPLEARTRDYSSLPPRRTHY-QPRTPQRPGPPLHSASSLPASRGARPSQVSPWPQGMARCVKKHRTPRENASSLCSASERSELKPSPQGKAPIPEAAALPQGDGSTDLDSKLTQQLIEFEKSLSGPSTEPDKILRHFSIMDFNSEKDIFRGSSKLVTQHELPERRKALRPPPPRPCTPAPTPAHLLGDQNLRPEPPLAMRPSRPAPLPPSAQQRTTAGATKLLTCNRPAWEPKEKEHPENMEKTLDQTSQCPLVLVKIQEMEQDLDMCLRAQEELNLLLEEKQEESLRAETLENLKLCESNIESLNLELQQLREMTLLSSQSLSPVAPSGSVSTENPEQRMLEKRTKVIEELLQTERDYIRDLEMCIERIMIPLQQAQIPNIDFEGLFGNMQMVIKVSKQLLADLEISDAV----------GPVFLDHRDELEGTYKVYCQNHDEAISLLEIYEKDEKIQKHLQDFLADLKSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMELLNATPESHPDKVPLTNAVLAVKEINMNINEYKRRKDLVLKYRKGDEDSLMEKISKLNIHSIIKKSNRVSSHLKHLTGFAPQIKDEVFEETEKNFRMQERLIKSFIRDLSLYLQHIRESACVKVVAAVSMWDVCMEKGHKDLEQFEKVHRYISDQLFTHFKERTERLVISPLNQLLSMFTGPHKLVQKRFDKLLDFYNCTERAEKLKDKKTLEELQSARNNYEALNAQLLDELPKFHQYAQGLFSNCVHGYAEAHCDFVRQALEQLKPLLSLLKVTGREGNLIAVFHEEHSRVLQQLQVFTFFPESLPATKRPFERKTTDRQSTRKPLLGLPSYMRQSEELRASLLARYPPEKLFQAERNFNAAQDLDVSLLEGDLVGVIKKKDPMGSQNRWLIDNGVTKGFVYSSFLKPYNARRSHSDVSVGSHSSTESEPGGSSPRVPRRQNSGGTLTFNPSSMAVTFSAGPGQKQPPDAASPREVDQGALSASFHP---ESSPCRCPSDPDSPSQQRPWDLADAAARDAHQPGPALRSC-RNSRHPEMAGHVVPGRSGQGRDLVKAGTRAAPTADDRNGEPGSSEAEGNQVYFAVYSFKARNPNELSVSANQRLKILEFKDVTGNTEWWLAEVNGKKGYVPSNYICKTEYT", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q6TXD4-1", "uniprot_id": "DNMBP_MOUSE", "id": "Q6TXD4-1", "name": "Dynamin-binding protein", "aln": "MEPGSMVRAIFDFCPSVSEELPLFVGDVIEVLAVVDEFWLLGKKEDVTGQFPSSFVEIVTIPSLKEGERLFVCICEFVSRELNSLSLHRGDLVILDDSAPTAGWLQGRSCWGAWGFFPSSCVQELCLSSRSRRWHAQSALLQAPEYSLGQARALMGLSAQLDEELDFREGDLITIIGVPEPGWFEGELEGRRGIFPEGFVELLGPLRTVDESVNSRSGDDSAVNGEVDVPPEEAESGGDEDDQQSGTYGIALYRFQALETNELDFEVGDRIQILGTLEDGWLEGCLKGKTGVFPHRFVKLCPSNRTEETTAQPQESSFPKDSESSVGKSGDSVVEEAR-QEPWECEEERPDYDLPGQASVPQDHVAPEWTGDTISGQDKDASGS---SPDVDLERPLAKDLSTPDPSEEVNGVSSQPQVPIH-PKVQKSQHYLTAGGSHQTSDPFSELVPLEARTRDYSSLPPRRTYA-QGWSFQKPASHLQRASSLTASRLDRPSHFCHP--AMASYAQKHQTSTENTASLHDPPERPERRPGLQDRGPATDITTASQGD-SLDLDSKLTQQLIEFEKSLSGPSTEPETIVRRFSIMDFYSEKDIVRGSSNSLPSQAFPERRKTLRPPPPRPRTPTPISSHLLVDQSPKPVPTLVVRPSRPAPLPPPAQQRMNTASPKPTSCAHPGWEAPEKEDSEHMEKSPAQTFPCPSMLARIRDVEQDLDTCTRAQEELNLLLEEKQDDPSRAETLETLRSYESTIQSLTLELQQLRDMTLLSSQSSSLAAPFGSVSTENPEQRMLEKRAKVVAELLQTERDYIRDLEMCIERVMVPLQQAQVPNVDFEGLFGNMQTVIKVSKQLLAALEISDAVGMSSCDCLVPGPVFLDHRDELEGTYRVYCQNHDEAISLLEMYEKDEKTQKHLQDYLADLK------GCTNYINLGSFLIKPVQRIMRYPLLLMELLNSTPESHPDKVPLTNAVLAVKEINVNINEYKRRKDLVLKYRKGDEDSLMEKISKLNIHSIIKKSSRVSSHLKHLTGFAPQLKDEVFEETEKNFRMQERLIKSFIRDLSLYLQHIRESACVKVVAAMSIWDLCMERGHHDLEQFEKVHRYISDQLFTRFKERTERLVINPLNQLLNMFTGPYKLVQKRFDKLLDFYNCTERAEKLKDKKTLEELQSARNNYEALNSQLLDELPKFQQYAQSLFTNCIHGYAEAHCDFVQQALEQLQPLLSLLKATDREGNLIAIFLEEHSRVLQQLQVFTFFPESLPAPRKPFERKTTDRQSSRKTLLGMPSYMLQSEELRSSLLARYPPEKLFHVQRNFNAAQDLDVSLLEGDLVGVIKKKDPMGSQNRWLVDNGVTKGFVYSSFLKPYNPRCSHSDASVASHSSTESEHSGSSPGC-HRQNSHSALTFNSNNMTVSFTSGLALTQPQDASPLKDCAHETLAVSWNTGHPETGPSTCSSDPGFSCQRRLGNPAD-GARDISQPASTLRGCQRSSPHSEVVGYSVPGRNDQGSDSIKGSARVCQAPEDRDRGVGSSETEGNQVYFAIYTFKARNPNELSVLANQRLRIHEFKDVTGNTEWWLAEVNGRKGYVPSNYIRKTEYT", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.**:*********************:*****************************:************:***.**.* *****.**********. . *.******.**** ********:******:**:**:****** ****:***********************:*****:**********:************************.. . ** ***.*.. * :**.:*.**************.*********:*:************.***:**:**:*******.. .**: .*:*.:.: .::.:. * :*. * . :* * . *:.: :. . . :*::.* :. * * .. *. **. . *: *.: **.:*** :***:*** *.:* *.:*:.* * ***: :.* :*: :***************** * : *:*.. *: **** *** ***:.. .:* .:** *. *.::*: ...:*.* :*. *.:.* : : .*** * ******************** .**:.*:*:****** *****.****: :..: :*****:******** **:. ..*: **. : *.*.:**********.**** .: ..* :* :*.**. *** .*:::*: ** ** :*.:*:::***** * **************::. *****:.*. *..*:**.:******:******** * ** ****************:**: *******************:*.******:**:********** *********: ***** : ***************:**************:****** ****** ***** ******************:************:************.*********:***************************************.***************:********************************************:*:**:***:**:******************.**********.******.*****:*******************************************:*********:****.**:**:***********:******:*******.*.*******:* *********************:.::****** ****:**.:**:**** ******:************:.:***********************************:******************.* ****.**.******** ..*** :**** .:****...*:*:*::* .** **:. : : :*:.* :. * .*. *.***. ..*:* : .* ..** **..:**.. *.. *.*:.* *.**..*. * :*..:*.. :**. ***:********:*:*********** *****:* ******************:********* *:***", "identical_positions": 1110, "similar_positions": 292, "identity": "69.51%" }, { "cls_id": "homologset.oma.818781", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A1IGU3-1", "uniprot_id": "ARH37_RAT", "id": "A1IGU3-1", "name": "Rho guanine nucleotide exchange factor 37", "aln": "MADFETDE-ASSKSESPEQ---EGQGSEDKSLLHQRLAIRELIDTEVSYLHTLRLCTSDIRGHLQ--QLPPGDLDILFSNIDDIIQVSSRFLHGLQETACKEEKQAHLIGNLFLEFQEELEQVYKVYCANYDQALLLVKAYQKEPELQKEIQGIIEAAVPQAGPSGLSFLLVIPLQRITKYPLLLQKILENTPADASAHPVLQRATSALQDVNSNINEYKMRKEVALKYTKVEQLSLRERLARINTHTLSKKTTRLSQLLKQEAGLVPRTEDKEFDDLEERFQWVSLCVTELKSNVAAYMDNLEAFLCFRPHERNLDIPGGAAEQYCSLARDLQLQAFLQFKQRLTGLVWQPLCSLARALVGPQNLIKKRLDKLLDFERVEEKLLDVGSVTYEEEAARHTYQALNSLIVAELPQFNHLVMQWLGQILRTFVVLQRDLADQVLRRAESSMALLPHRHVSEPDFQKLLEDTLGQSSSQLRHFRESFEKVLPPSTSQPLLPGSEHQMQSLLTRYGPGKIYQVTSNINGTGTLDLTLPRGQIVALLQNKDTKGNNSRWLVDTGGHRGYVPAGKLQLYHPINPSEKEPRRQTGMPEDY-----WLPTPEPTQPSVPTVPTMSQVVAVYPFVARSTHELSLQAGQPVTILEAQDKKGNPEWSLVEANGQRGYVPSNFLARTPSPTPRGWNLPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A1IGU4-1", "uniprot_id": "ARH37_MOUSE", "id": "A1IGU4-1", "name": "Rho guanine nucleotide exchange factor 37", "aln": "MADFGADE-ASSKSESPEQ---EDQGSEDRSLLHQRLAIRELIDTEVSYLHTLRLCASDIRSHLQ--QLPPGDLDILFSNIDDIIQVSSRFLRGLQETACREEEQAHLIGNLFLEFQEEFEQVYKVYCANYDQALLLVKAYQKEPELQKEIQGIIEAAMPQAGPSGLSFFLVIPLQRITKYPLLLQKILENTPADASAHPALQRATSALQDVNGNINEYKMRKEVALKYTKVEQLSLRERLARINTHTLSKKTTRLSQMLKQEAGLVSRTEDKEFDDLEERFQWVSLCVKELRNNVVDFMGNLEVFLSFRPHERSLDIPGGPAEQYCSLARDLQLHAFLQFKQRLRSLVWQPLCSLARALAGPQNLIKKRLDKLLDFDRVEEKLLDVGSVTWEEEAARHEYQALNSLLVAELPQFNQLVMQWLGQILCTFVVLQRDLADQVLRRAESTMALLPHHHVSEPDFQKLLEHTLGQSSSQLRLFQESFEKVLPPSTTQPLLPGSEHQMQALLTRYGPEKLYQVSSNINGTGTLDLTLLRGQIVALLQNKDTKGNNSRWLVDTGGHRGYVPAGKLQLYHPIIPSEKELRGQTGTHEDS-----WLPAPEPTQLSVPTVPTMSQVVAVYPFVARSTHELSLQAGQPVTILEAQDKKGNPEWSLVEANGQRGYVPSNFLARTPSPTPWGWNLPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1MJ96-1", "uniprot_id": "F1MJ96_BOVIN", "id": "F1MJ96-1", "name": "Rho guanine nucleotide exchange factor 37", "aln": "MTNHGDDA-LSSRTGAPDG---DDRLSEDRSLLQQRLAVRELIDTEVSYLHVLQLCASDIRSRLQ--QLPQGDLDVLFSNIDDIIKVNSRLLHDLQETASREEEQVQLIGNAFLEFQEELEQVYKVYCASYEQALLLVETYRKEPELQREIQGIIEAVLPQAGPSGLSFLLVIPLQRITKYPLLLQKILENTLPDASAYAVLQRATSALQDVVTNINEYKRRKEVASKYTKVEPLSLRERLARINTHTLSKKTTRLSQLLKQEAGLVPRTEDKEFDDLEERFHWVSLCVTELKSNVAAYLDNLEAFLRFRPQDYNLEIPEGPVVQYCYLARDLQLQAFPEFKQQLEAQVWQPLCSLAKALAGPQNLIKKRLDKLLDFERVEEKLLEVGSVTYEEEAARHTYQALNSLLVAELPQFNQLAMRWLGQILCTFVTLQRDLAKQVLQRAEDSLAQLPHHHLSEPAFRKLVEDALGQTSHQLRSFQENFEKVLPPPTTQPLLPGAERQVQALLSRYP-GKLYQVTSNISGAGTLDLTLPRGHIVALLQNKDTKGNSSRWLVDTGGHRGYVPAGKLEVYH-VVPSEEEER----PHRDS-----QHQTPEPISAPVPSVPAVTQVVAMYPFMARSSHEVSLQAGQRVTVLEAQDKKGNPEWSLVEVNGQRGYVPSSFLARAPSPAPWGWSLPS", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1RL91-1", "uniprot_id": "F1RL91_PIG", "id": "F1RL91-1", "name": "Rho guanine nucleotide exchange factor 37", "aln": "MAEPADDE-LSSRTGSPDG---EGLVSEDRSLLHQRLAVRELVDTEASYLHVLQLCASDIRGRLQ--QLPQEDLDVLFSNIDDVIKVNSRLLRDLQDAASRGEEQVRLVGDVFLEFQEELEQVYKVYCASYEQALLLVENYQKDPELQRGIQRTIEAVLPQAGPSGLSFLLVNPLQRVTKYPLLLQKILENTLPDASAYPVLQRAASALQDVVTHINEYKRRKEVASRYTKVEQLSLRERLARINTHTLSKKTTRLSQLLKQEAGLVPKLEDKEFDDLEEKFHCVSLCVTELKSNVAAHLDALEVLLRFRPHESHLDIPGGPVAQYGDLARDLQLQAFPQFKQRLEGLVWQPLCSLAKALAGPQNLIRKRLDKLLDFERAEEKLSEVGSVTYEEEAARHTYQALNSLLVAELPQFNQLAVQWLRQILCTLVTLQGDLAKHVLQRAESSLAQLPHHHLSEPAFRDLVADTLDQAGHQLRSFQENFEKVLPPPTTRPLLPGAERQVQALLSRYGSGKLYQVTSNISGSGTLDLTLPRGHVVALLQNKDTKGNSSRWLVDTGGHRGYVPAGKLELYR-VAPSEEDLRGQAKPHENS-----RQLTPEPTLAPVPSVPAVTQVVAVCPFAARSSHEVSLQAGQQVTVLEAQDKKGNPEWSLVEVNGQRGYVPSSFLARVPGPAPWGWSLPS", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A1IGU5-1", "uniprot_id": "ARH37_HUMAN", "id": "A1IGU5-1", "name": "Rho guanine nucleotide exchange factor 37", "aln": "MAKHGADE-PSSRSGSPDR---EGRASEDRSLLHQRLAVRELIDTEVSYLHMLQLCASDIRSRLQ--QLPQGDLDVLFSNIDDIIKVNSRFLHDLQETASKEEEQVQLVGNIFLEFQEELEQVYKVYCASYDQALLLVDTYRKEPELQRHIQGIVEAVVPQAGSSGLSFLLVIPLQRITRYPLLLQKILENTVPDASAYPVLQRAVSALQDVNTNINEYKMRKEVASKYTKVEQLTLRERLARINTHTLSKKTTRLSQLLKQEAGLIPRTEDKEFDDLEERFQWVSLCVTELKNNVAAYLDNLQAFLYFRPHEYNLDIPEGPAVQYCNLARDLHLEAFLKFKQRLEGLVWQPLCSLAKALLGPQNLIKKRLDKLLDFERVEEKLLEVGSVTYQEEAARHTYQALNSLLVAELPQFNQLVMQWLGQIMCTFVTLQRDLAKQVLQRAEGSMAQLPHHHVPEPAFRKLVEDALGRTSNQLRSFQETFEKVQPPPTTQPLLPGSERQVQALLSRYGPGKLYQVTSNISGTGTLDLTLPRGQIVAILQNKDTKGNSGRWLVDTGGHRGYVPAGKLQLYH-VVPSAEELRRQAGLNKDP-----RCLTPEPSPALVPSIPTMNQVIAAYPFVARSSHEVSLQAGQPVTILEAQDKKGNPEWSLVEVNGQRGYVPSGFLARARSPVLWGWSLPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0XSL8-1", "uniprot_id": "A0A8V0XSL8_CHICK", "id": "A0A8V0XSL8-1", "name": "", "aln": "MASTHAEEPLAEDTADHDAHIYEEVMLSERMEHSQRLAVEELITTEASYVHNLQLCLSDIRAHLQKKQLPGLDLEGLFSNIDDILHVSRRFLRGLQDTATQEHEQLLSISTLFQEFKEEMEMVYKIYCASYEHALLLVESYRKDPRLQEEIMDTLTATVPHTSASDLSFFLVMPVQRVTKYPLLLGKILENTPANTSTHEALAAAVRAMTQVNANINEYKRRREVATKYNKAEQLTLRDRFARLNTHSIAKKTTRLSRLLMHEAGIVAKTEDKEYDELEEKFQSVASSVTALKENVASYLQHLEAFLLPTPHRCELQMEEGPAQQYRRFAEHLHRAVFPEFRRRLDRLVWKPLCRLAEMLVGPQQLVKKRLDKLLDYEEIQERKSETGSVTYDEEAAMNTYLAINALLVAELPRFNQVAMQLLGQLLGSFSVLQQDLATEVLHEAKKEVEQMPHGHMLLPAFWRMVEDTLQQSGVQLRTFIQAFETVTPSPLLQPLNPAEERKVLSLVSKHGPDKLYQVTSNVSGSKDMDLTLQRGQIVALLQSVDTKGNTGRWLVDAGGPRGFVPAAKLQPYS-LGPSQQPKMQMPALESGTERRRHSYVSPEAPKPQVATFTPAFQVVAGFSFTARSPQELSLQAGQPVVVLEPHDKKGSTEWSLVEVNGQRGYVPSSYLLTVPVQEPVGWSLPV", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:. : :. : : : .:: ****:.**: **.**:* *:** ****.:** *** **: *******:::*. *:*:.**::* : .:* :. * **:**:* ***:***.*::*****. *:*:*.**. * : *.:*::..*.***:** *:**:*:***** ****** .::*:: .* *. *: :* :***** *:*** :*.*.* *:**:*:**:***:::*******::* :***::.: ****:*:***:*: *: .*. *:.**. .: *:.:* *: *:: *.. ** :*..*: .* :*:::* **:*** **. * ***:*::********::. :*: :.****::**** : * *:*:*:*****:**::.:: * *:: :: .** *** .**:.*: : :** *: * * :: .:* ::. *** * : **.* *.. :** *. *::: :*:::: *:***:**:.*: :**** **::**:**. *****..*****:** **:***.**: * : ** : . :**. *.:... **:* .* ***.:*:****** *.:**.:****..******.*********.:* . **.** ", "identical_positions": 302, "similar_positions": 213, "identity": "43.96%" }, { "cls_id": "homologset.oma.818782", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6XZF7-1", "uniprot_id": "DNMBP_HUMAN", "id": "Q6XZF7-1", "name": "Dynamin-binding protein", "aln": "MEAGSVVRAIFDFCPSVSEELPLFVGDIIEVLAVVDEFWLLGKKEDVTGQFPSSFVEIVTIPSLKEGERLFVCICEFTSQELDNLPLHRGDLVILDGIPTAGWLQGRSCWGARGFFPSSCVRELCLSSQSRQWHSQSALFQIPEYSMGQARALMGLSAQLDEELDFREGDVITIIGVPEPGWFEGELEGRRGIFPEGFVELLGPLRTVDESVSSGNQDDCIVNGEVDTPVGEEEIGPDEDEEEPGTYGVALYRFQALEPNELDFEVGDKIRILATLEDGWLEGSLKGRTGIFPYRFVKLCPDTRVEETMALPQEGSLARIPETSLDCLENTLGVEEQRHETSDHEAEEPDCIISEAPTS-PLGHLTSEYDTDRNSYQDEDTAGGPPRSPGVEWEMPLATDSPTSDPTEVVNGISSQP-QVPFHPNLQKSQYYSTVGGSHPHSEQYPDLLPLEARTRDYASLPPKRMYSQLKTLQKPVLPLYRGSSVSASRVVKPRQSSPQLHNLASYTKKHHTS-----SVYSISERLEMKPGPQAQGLVMEAATHSQGDGSTDLDSKLTQQLIEFEKSLAGPGTEPDKILRHFSIMDFNSEKDIVRGSSKLITEQELPERRKALRPPPPRPCTPVSTSPHLLVDQNLKPAPPLVVRPSRPAPLPPSAQQRTNAVSPKLLSRHRPTCETLEKEGPGHMGRSLDQTSPCPLVLVRIEEMERDLDMYSRAQEELNLMLEEKQDESSRAETLEDLKFCESNIESLNMELQQLREMTLLSSQSSSLVAPSGSVSAENPEQRMLEKRAKVIEELLQTERDYIRDLEMCIERIMVPMQQAQVPNIDFEGLFGNMQMVIKVSKQLLAALEISDAVGPVFLGHRDELEGTYKIYCQNHDEAIALLEIYEKDEKIQKHLQDSLADLKSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMELLNSTPESHPDKVPLTNAVLAVKEINVNINEYKRRKDLVLKYRKGDEDSLMEKISKLNIHSIIKKSNRVSSHLKHLTGFAPQIKDEVFEETEKNFRMQERLIKSFIRDLSLYLQHIRESACVKVVAAVSMWDVCMERGHRDLEQFERVHRYISDQLFTNFKERTERLVISPLNQLLSMFTGPHKLVQKRFDKLLDFYNCTERAEKLKDKKTLEELQSARNNYEALNAQLLDELPKFHQYAQGLFTNCVHGYAEAHCDFVHQALEQLKPLLSLLKVAGREGNLIAIFHEEHSRVLQQLQVFTFFPESLPATKKPFERKTIDRQSARKPLLGLPSYMLQSEELRASLLARYPPEKLFQAERNFNAAQDLDVSLLEGDLVGVIKKKDPMGSQNRWLIDNGVTKGFVYSSFLKPYNPRRSHSDASVGSHSSTESEHGSSSPRFPRQNSGSTLTFNPSSMAVSFTSGSCQKQPQDASPPPKECDQGTLSASLNPSNSESSPSRCPSDPDSTSQPRSGDSADVARDVKQPTATPR-SYRNFRHPEIVGYSVPGRNGQSQDLVKGCARTAQAPEDRSTEPDGSEAEGNQVYFAVYTFKARNPNELSVSANQKLKILEFKDVTGNTEWWLAEVNGKKGYVPSNYIRKTEYT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0R4F8-1", "uniprot_id": "DNMBP_RAT", "id": "M0R4F8-1", "name": "Dynamin-binding protein", "aln": "MEPGSVVRAIFDFCPSVSEELPLFVGDVIEVLTVVDEFWLLGKKEDVTGQFPSSFVEIVTIPSLKEGERLFVCTCDFISREPNSLSLHRGDLVIIDGTPTAGWLQGRSSLGARGFFPSSCIHELCLSSQSRQWHSQNMLLQVPEYSMGQARALMGLSAQLDEELDFREGDVITIIGVPEPGWFEGELEGRRGIFPEGFVELLGPLRTADESVNAGSGDDSTLNDEVDVSPEEVESEGDEDDQQAGTYGIALYRFQALESNELDFEVGDKIRILGTLEDGWLEGRLKGKTGIFPHRFVKLCPSNRSEETMALPQGDSFPKNSESSAGEMGDSV-VEEARQDPQECEEETPDSGLPEQTSEEPLDHVAPECVVDKISGQDEDASGS---SPDVDLEGPRAEDPSTPDLSQEVNGISSLPPQVPLQPEEEKSQHYLTAGGSRQCPDTFSKLFPLEAKTRNYSSLPPRRTYTQGWSLQKPAPHLHRASSLTASRVNRPGHFS--HTAMASCAQKHQTSAENAASLCCAPERPKRRPGLPDKEPATEITPASQGD-NLDLDSKLTQQLIEFEKSLSGPSTEPKKIVRRFSIMDFYSEKDIVRGSSNSLPSRNFPERRKALRPPPPRPHTPTSTSPHLLVDQSPKPGPPLVVRPSRPAPLPPPTQQRLNTASPKPTSCALPGWEAPEKEGSEYTEKSPAQLFPCPSVLARIQDVEHDLDMHTRAQEELNLLLEEKQDESLRAETLETLKSYESTIQSLNLELQQLREMTLLSSQSSSLAAPSGSVSTEKPEQRMLEKRAKVVAELLQTEKDYIRDLEMCVERVMVPLQQAQVPNIDFEGLFGNMQTVIKVSKQLLAALEITDAVGPVFLDHRDELEGTYRLYCQNHDEAISLLDIYEKDERIQKHLQDYLADLKSLYHEWGCTNYINLGSFLIKPVQRIMRYPLLLMELLNSTPESHPDKAPLTSAVLAIKEINANINEYKRRKDLVLKYRKADEDSLMEKISKLNIHSIIKKSSRVSSHLKHLTGFAPQLKDEAFEETEKNFRMQERLIKSFIRDLSLYLQHIRESACVKVVAAMSIWDLCMERGHHDLEQFEKVHRYISDQLFTRFKERTERLVINPLNQLLNMFTGPYKLVQKRFDKLLDFYNCTERAEKLKDKKTLEDLQSARNNYEALNSQLLDELPKFQQYAQSLFTNCIHGYAEAHCDFVQKALEQLQPLLSLLKASDREGNLIAIFHEEHSRVLQQLQVFTFFPEALPAPRKPFERKTTDRQSSRKALLGMPSYMLQSEELRSSLLARYPPEKLFHVQRNFNAAQDLDVSLLEGDLVGVIKKKDPMGSQNRWLVDNGVTKGFVYSSFLKPYNPRCSHSDSSVVSHSSTESEHSGSSPSFHRQNSSSALTFNSNSMTVSFTSGLPQKQPQDTSP-LRECVPETLGVSSNTGNPETGPSPCPSDPGFSCQRRPGNPADGTREISQPASTLRGCQRRSLHSEVLGYPVPGRSDQGSDSIKGTSRACQTAGDRDRGLGSSEAEGNQVYFAIYTFKARNPNELTVLANQRLRILEFKDVTGNTEWWLAEVNGKKGYVPSNYIRKTEYT", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.************************:****:**************************************** *:* *:* :.*.********:** **********. **********::**************. *:*:*****************************************************************.****.:*. **. :*.***.. * * ***:::.****:*********.**************.********* ***:*****:*******..* ******** .*:.: .*:* . : ::: *** *::..: * * **. :.* .:. **.*::.* .*: * ****::*. **.*: * * * *..*.* :: ****** * ***::*: :***:* *.***: .: :..*:****:**:*:****:* *:* :****. *:*.**::**** :* : * :** ::**:** *: . .** : :** : . * :. **** . *****************:**.***.**:*:****** **********: :..:::************** **.**********. **.***************.:*** *:.*** * * *: ****. : :* * *** **.**:::*:****::********:******** ****** ** **.*:***:******************.*******:*:************: ******:*********:**:***:****************** **************:********.*********::*********:**:******:******* ********:********************:*********************.***.****:****.*****************.*********************.***************:***.****************************************:*:**:******:******:***********.**********.******.*****:******************************:************:*********:****.*****:***********::*****:*******.:.****************************:***.:******* ****:**.***:***********:************:.:***********************************:******************** ****:** *********..*** * ****.*:****..**:****** ******:** :** **..* *..*.*:.** *****. :.* *.*:.** :*::.**::* * . *. *.*::**.****..*..* :** :*:.*:. **. ..***********:***********:* ***:*:************************************", "identical_positions": 1191, "similar_positions": 255, "identity": "75.14%" }, { "cls_id": "homologset.oma.818842", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZIE4-1", "uniprot_id": "FYB1_RAT", "id": "D3ZIE4-1", "name": "FYN-binding protein 1", "aln": "MDGKTDVKSLMAKFNTGSNPTEEVSTSSRPFKVAGQNSPSGIQSKKNLFD---NQGNASPPAGPSNMSKFGTTKPPLAAKPTYEEKSEKEPKPPFLKPTGVSPRFGTQPNSVSRDPEVKVGFLKPVSPKPTSLTKEDSKPVILRPPGNK--LHNLN-QESDLKTLGPKPGSTPPVPENDLKPGFSKIAGAKSKFMPAPQDADSKPRFPRHTYGQKPSLSTEDAQEEESIPKNTPVQKGSPVQLGAKSRGSPFKPAKEDPEDKDHG--TPSSPFAGVVLKPAASRGSP--GLSKNSEEKKEERKTDIPKNIFLNKLNQEE------PARFPKAPSKLTAGTPWGQSQEKE-GDKDSATPKQKPLPPLSVLGPPPSKPSRPPNVDLTRFRKADSANSSNKSQTPYSTTSLPPPPPTQPASQPPLPASHPAH--LPAPSLPPRNIKPPLDLKHPINEENQDGVMHS----DGTGNLEEEQESDGEMYEDIE---SSKERDKKREKEEKKRLELERKEQKEREKKEQELRKKFKLTGPIQVIHHAKACCDVKGGKNELSFKQGEDIEIIRITDNPEGKWLGRTARGSYGYIKTTAVKIDYDSLKRKKNTINAVPPRPVEEDQDVYDDVAEQDAPNSHS--QSGSGGMFPPPPADDDIYDGIEEEDADDGSVPQVDEKTNAWSWGILKMLKGKDERKKSIREKPKVSESDSNEGSSFPSPH-KQL--DVG-EEVYDDVDASDFPPPPAEMS--QGMSVGKTKAEEKDPKKLKKQEKEEKDLRKKFKYDGEIRVLYSTKVASSLTSKKWGTRDLQIKPGESLEVIQSTDDTKVLCRNEEGKYGYVLRSYLVDNDGEIYDDIADGCIYDND", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35601-1", "uniprot_id": "FYB1_MOUSE", "id": "O35601-1", "name": "FYN-binding protein 1", "aln": "----------MAKFNTGSNPTEEAATSSRPFKVAGQSSPSGIQSRKNLFD---NQGNASPPAGPSSMPKFGTTKPPLAAKPTYEEKPEKEPKPPFLKPTGGSPRFGTQPNSVSRDPEVKVGFLKPVSPKPTSLTKEDSKPVVLRPPGNK--LHNLN-QESDLKTPGPKPGPAPPVPENELKPGFSKVAGAKSKFMPAAQDTDSKPRFPRHTFGQKPSLSTEDSQEE-NTSKNVPVQKGSPVQLGAKSKGAPFKPPKEDPEDKDHG--APSSPFPGVVLKPAASRGSP--GLSKNFEEKKEDRKTDLAKNIFLNKLNQEE------PARFPKAPSKLTAGTPWGQSQEKE-GDKNSATPKQKALPPLSVLGPPPPKPNRPPNVDLTRFRKADSANSATKSQTPYSTTSLPPPPPTHPASQPPLPASHPAH--PPVPSLPPRNIKPPLDLKHPINDENQDGVMHS----DGTGNLEEEQESEGETYEDID---SSKERDKKREKEEKKRLELERKEQKEREKKEQELKKKFKLTGPIQVIHHAKACCDVKGGKNELSFKQGEDIEIIRITDNPEGKWLGRTARGSYGYIKTTAVEIDYDSLKRKKNSLNAVPPRLVEDDQDVYDDVAEQDAPNSHG--QSGSGGMFPPPPTDDEIYDGIEEEDDDDGSVPQVDEKTNAWSWGILKMLKGKDDRKKSIREKPKVSESDNNEGSSLPSQH-KQL--DVG-EEVYDDVDASDFPPPPAEMS--QGMSVGRAKTEEKDPKKLKKQEKEEKDLRKKFKYDGEIRVLYSTKVASSLTSKKWGARDLQIKPGESLEVIQSTDDTKVLCRNEEGKYGYVLRSYLVDNDGEIYDDIADGCIYDND", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15117-1", "uniprot_id": "FYB1_HUMAN", "id": "O15117-1", "name": "FYN-binding protein 1", "aln": "----------MAKYNTGGNPTEDVSVNSRPFRVTGPNSSSGIQARKNLFN---NQGNASPPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVN-QDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGP--GLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQ--PPVPSLPPRNIKPPFDLKSPVNEDNQDGVTHS----DGAGNLDEEQDSEGETYEDIE---ASKEREKKREKEEKKRLELEKKEQKEKEKKEQEIKKKFKLTGPIQVIHLAKACCDVKGGKNELSFKQGEQIEIIRITDNPEGKWLGRTARGSYGYIKTTAVEIDYDSLKLKKDSLG-APSRPIEDDQEVYDDVAEQDDISSHS--QSGSGGIFPPPP-DDDIYDGIEEEDADDG----------------------------------------------FPAPP-KQL--DMG-DEVYDDVDTSDFPVSSAEMS--QGTNVGKAKTEEKDLKKLKKQEKEEKDFRKKFKYDGEIRVLYSTKVTTSITSKKWGTRDLQVKPGESLEVIQTTDDTKVLCRNEEGKYGYVLRSYLADNDGEIYDDIADGCIYDND", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0YKE3-1", "uniprot_id": "A0A8V0YKE3_CHICK", "id": "A0A8V0YKE3-1", "name": "FYN-binding protein 1", "aln": "MDGKADVKSLMAKFNGGNSPSEDVSGNIRLSKVTGQPTHSGLQTRKAVFEKFASQGNAASPSGPSVSQKPAHPKPPLAVKPSTEDKTEKDPKPPYLKPVG--QRFGVQLQATNRESDGKAGYTKTLT-KSSDLAKEEPKSLYPKLAGNK--LHNSAPQEKEKRPLGTKPNFNSEAQESEEKTSFSKVAGAKEKFMSATQENDPKPSSSKPALAQKPSLNHAAPHNEDTSSKNVFPHKG---LAGPRPNMHSFKATKETDENSNCAAETAGSHFSNMALKPTGHWSSASQGTPRNAEEKTEEKGVSATRNIFLNKIIQEE--SGSSPPKFHKTSTAFAAGRSLGGSEEKDDRDRSSGAPKRKSLPPLFKLGQPPQKPSRPPSVDLERFQKSIPRDSPKN--EGFKQMAPSPAAASAPAP-PPPPSSHPSLHAPAAPSLPPRNVKPSSETTNPDTEENYDDVEFLLQGRMGPGNKDGDQGSDGEMYEDINDIRTSREKEKKSEKEEKKRMDQEKKEQKEKEKKEQEIRKKFKLTGPIQVLHQARACVDSKGGKNELTVKQGDQIEIIRLTDNPEGKWLGR-IKGCYGYIKTTVVEIDYDSLKTKQQAVVKQP----EIDQEVYDDVGEQDSISSQSGGRNGAGNMFPPPPSDQEIYDGVDDTDSVPRSVSQDEDKNDIWSWGILKKLKVKDDKKKSVREKTTKVNGAEDNGDLFRSPSTKQFGKDCGDSDVYDDVDSSDFPPPPPEFNLPKSVSLGKGKSDEKYPQKLKMMEREEKEFRKKFKFEGEIKVLYSTTTVQDLSQRKWGSKDLQIKPGETLEVIQSTDDTKVLCRNEEGKYGYVLRSNLVENDGEIYDDIGEDCIYDND", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:* *..*:*:.: . * :*:* : **:*::* :*: .****:.*:*** * . .***:*.**: *:*.:*:****:***.* ***. . ..*:.: *.*: *.: *. .*.**:.*. .*** **. *: : :. *.*.. . . *.: * .*.*::*.* ***.*.*: :.** .: : .***.*. .::: . **. ** * :.. .:*..:* *:.: . .. *..:.***:. ... * .:* ***.*:: . .:* * .*: *** *.:* *:.: ::.* . * *:**: *:.*.:**:*.**** ** ** **.***.*** :*:*: . :*..: :. : .*...: **. ** *:***: ..*******:**. : . * .::* *.* . *.** : :* *:** ****: :*:*::** *******:: *:*****:******::***********:* *:** * *******:.***::*****:*********** :*.*******.*:******* *:::: * * **:*****.*** .*:. :.*:*.:***** *::****::: * : : **: * * .:******:**** ...*:. :. .:*: *::** :*** *:***::*****::***:*****... .::.:***::***:****:*****:********************* *.:*********.:.******", "identical_positions": 366, "similar_positions": 253, "identity": "42.36%" }, { "cls_id": "homologset.oma.818843", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5VWT5-1", "uniprot_id": "FYB2_HUMAN", "id": "Q5VWT5-1", "name": "FYN-binding protein 2", "aln": "----------------------------------------------------------------------------MEGEGVRNFKELRAKFQNLDAPPLPGPIKFPAGVSPKGDIGGTQSTQILANGKPLSSNHKQRTPYCSSSESQPLQPQKIKLAQKSEIPKCSNSPGPLGKSTVCSATSSQKASLLLEVTQSNVEIITKEKVMVANSFRNKLWNWEKVSSQKSEMSSALLLANYGSKAIHLEGQKGMGLTPEEPRKKLETKGAQTLPSQKHVVAPKILHNVSEDPSFVISQHIRKSWENPPPERSPASSPCQPIYECELASQAPEKQPDVRHHHLPKTKPLPSIDSLGPPPPKPSRPPIVNLQAFQRQPAAVPKTQGEVTVEEGSLSPERLFNAEFEEPHNYEATISYLRHSGNSINLCTAKEIADPTYEVGIEELQKPGKNFPYPEPSAKHED--KKMKEKQPCELKPKNTEKEPYSNHVFKVDACEGTPEKIQMTNVHTGRRNMLAGKQEAMIDIIQTNPCPEGPKLARHSQGHCGHLEVLESTKETPDLGVSKTSSISEEIYDDVEYSRKEVPKLNYSSSLASSSEEN-RELYEDVYKTKNNYPKIDLDGKEALKRLQQFFKKEKDRFKIKKTKSKENLS-AFSILLPDLELKS----QEVIIYDDVDLSEKESKDEDKLKMWKPKFLTPKEKKEKNGAEESESFSPRNFFKTKKQNLEKNRMKREEKLFRERFKYDKEIIVINTAVACSNNSRNGIFDLPISPGEELEVIDTTEQNLVICRNSKGKYGYVLIEHLDFKHQSWSP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1MCE3-1", "uniprot_id": "F1MCE3_BOVIN", "id": "F1MCE3-1", "name": "FYN-binding protein 2", "aln": "MEAGARPAAGESAPTPAEGGAAAQVGQVGSLSAGVSAARGSACSLAGAGRAKRALGLRIQLWEAGFVSQTLPRKKVMEAEGLRNFKELRAKFQNLDASSLSGPIKFPAGVSQKGDFGSRQSMKTSASGKPPSSSHNQHSPNCADGDPQPLKPQQVKGTQKSETQKCSNYLEQP--SFPGSAVRSQKASPLLDVYQSNGEIANKKKVMVNDSFRNKLWSWEVLS-QKSETPSIFLPASCGSRAFHLKEQKSIKLTSQEPMENMEIKEAQSLPSHRHLMAQRRLCAISEDPTVQPSQCSRESEANSSPERSLTGSICHPVYDNELTSQTSEEQPDARHPQLPNTKPLPSVESLGPPPPKPPRPPVVTLQAFQRQAAALSKPDGEEATKEGSLPP---VSAEFEEPHNYEATISYLRHSSNSINLCTAKKSADSTYEVRIEELRKAWKSFYHQELTPQHEDEDKQMKEKEPYQLKLQNTED-LHLDHLFKVDIYEEIPGKTQMAEDHTGGRIMPARKQDAAMDIIQVEACPEDFQPARLPIDYCGYAKALEMTKETQGQGAIKPNSISEN-YDDVECSG------------SKSS-----------------------DGKASLKRLQRFFKKEKDRLKVNRINSKENIR-AFSLSLPDLKLRS----QEVIIYDDVAINGKQPNDELKGKSWKLKFLTLKEKKKK-GAKESE----RSFFKIKKQNLQKDRMKREERLFRERFKYDKEITVINTAVVCSNNSRNGISDLPITPGEELDVIDITEENLVICRNSEGKYGYVLIEHLDFKQQV---", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A8I6A116-1", "uniprot_id": "A0A8I6A116_RAT", "id": "A0A8I6A116-1", "name": "FYN-binding protein 2", "aln": "--MEARPPEGGRSHCPGGAGGESRFQPV--------PDRGSDCTLAGGG--GSVVGPKIQLWEAGIVSQSEPRRTTMEEEGIRNFKELRAKFQKLNAVPLSGPIKLPAGVSRKDGRGYTQPSQDPANRKHLSSHHYRTPSNSSAGLSHPLKTQKIKSAQRDDVQK--SSLGTPENSTVYPERNFQKAAMPLDVNKSRSETSNEERGMTLSSFRCKLWNWEKVSSQKSEMSPTALLTNGRLKTFHLEGHKTMGLAQEKPEKNLKTTEAQPLPPQNHLMAQGKSPIASKASKGSLPRYSRKQTESPGTEGSHESSPCQPVYECELVSLVPEK-PESQHCQLPKTKPLPSIETLGPPPPKPSKPPFVNIYAFPRQPAVVSKSLKEVTTKESPLPPD---SAELEEAHNYDTTISYLRHSGNSINLCAAGESAEATYEIEIEELQKPQRGILLPELSPRPKDGENTTREKEPCASEPPKPGKVSYPKHPSKIAVCEGTPGKTQMSGVQENRRSMPAGNQQAIIDIIQSRHFQEDAMLTRHSQGKSGYVEALGVTKETPSPSTVRSSSSSEKTYDDVECSREDIQKWDFSSSFTSDSEENSEETYEDIYRAKTSDPKTDAAGRAALRRLQQLFSRENGVFRMKKTKSKEIVSNGFSMSLPDLGPRS----HDGIIYDDVDAREKES----KVKTWKAKFLTPRGKK-GKGSRGSKRFSPKNFFRTKKKKLEKNRVEKEEKLFRERFQYGKEIMVINRAVACSGNSRNGIFDLPITPGEQLEVIDTTEQNLVICRNSKGKYGYVLIEHLDFKHQG---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A995-1", "uniprot_id": "FYB2_MOUSE", "id": "A2A995-1", "name": "FYN-binding protein 2", "aln": "----------------------------------------------------------------------------MEEEGIRNFKELRAKFQKFNAAPLPGPMRFPAGVSRKHDRGSTQPAQDLANRKCLSSHHHQTPSHSSTGVSQPLKNQTLKSAQGDELQKTSSSSGTPEKSTVCPERDFQKAAVPLDVTKSRAKTSNEEKGMTLSSFRYKLWNWEKVSSQNGEMSPAPLLTNGGIKTFHFEGQKTMGLAQDKPEKSLKATGAQTLPPQSHSMAQRKSPVTSKASSVSLPPHSRKSTKSPATEGSHRSSQCQPVYECELDSLVPEK-PQSRHCRLPKTKPLPSIETLGPPPPKPSKPPFVNLYAFHRLPATVTKTPKEETMKEGPLSPD---SAELEEAHNYDTTISYLRHSGNSINLCAEGESTEATYEIEIEELQKPWRSFFLPELSPRPKEEENTMEEKESWESEPLEPRKELHPSRPPKVVVYKETPGKTQMAGVHEDRRSVPAGNQEAMTDIMQNRLFPEDVTLTRHSQDKSGYVEALEVTKETPSPSTIRSSSSSEKTYDAVECSREDVRKWDFSSSFTSDSEENCEEMYEDIYKAKNDDPKTEVAGRTALRKLQQIFRKENVVFRMKKTKSKEIVSNGFSVSLPDLGPRSQDDSQDGIIYDDVDTREKESNDEDKVKTWKTKFLIPKGKKWGKGSQGSKSFSPRHFFRTKKQKLEKNRMEKEEKLFRERFQYGKEILVINRAVACASNSRNGMFDLPIIPGEQLEVIDTTEQNLVICRNSKGKYGYVLVEHLDFKHQG---", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** **:***********:::* .*.**:::***** * . * *. : *. * ** * : .. .: . .:**: * :* :* .: * . * . ***: *:* :*. : .::: *. .*** ***.** :* *:.* .. * :. :::*:: :* : *: ::* :.:: . **.**.: * :* *: .. . *:. .. .* * .* *:*:*: ** * ..*: *: :* :**:******:::********.:**.*.: ** * .*.:.*. * : :*..*.* .**:**.***::********.******: : ::.***: ****:*. :.: * :.: :: : .**:. : :. . : .: *: : * * **: : . * : * :*:* **:* . *. :* . . .*: :.* **** . .. :..* **: ** ** * :..* *: :*::**::* :*: ::::: :*** : .**: **** :* :: ****** *:. * * ** *** : ** *:. *: : **: **::*:*:*:::**:******:*.*** *** **.*:.*****: **** ***:*:*** **:********:*******:******:* ", "identical_positions": 270, "similar_positions": 213, "identity": "33.25%" }, { "cls_id": "homologset.oma.818867", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHD6-1", "uniprot_id": "D3ZHD6_RAT", "id": "D3ZHD6-1", "name": "Putative RNA-binding protein 15B", "aln": "MKRQNERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGTKHPVPARARDKPRGSGG-GGGHRD--GRAAGDANHR--------ASSGRSSG-APGGGGRTGKASGDPGAGGAS------PRASPLP---------PPPPPPGAEP-----------AGPGT-TAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRFG-----EISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGG----SSRRSSSSSAAASTPPPGPPTPADPLGYLP-LHGGYQYKQRSLSPVAAPPLREPRARHAAAAFALD-AAAAAAVGLSRER--ALDYYGLYDDRGRPYSYQAVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLTDGYTRHRNLDADLRVRDRTPPHLLYSDRDRTFLEGDWTSLSKSSDRRNSLEGYSRSVRSRSGERWGADGDRSIAKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGGGQQSERGSDRTPERSRKENHSSE-GTKESGSNSLSNSRHSAEERSHHHHHHEAPDSSHGKKTRESERNHRTTEAEPKTLEEPKHETKKLKTLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVISGLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLAIQSTPSGPGAEG-MPMVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDSTGMLYAFPPCDFSQQYLQSALRTLGKLEEEHMVIVIVRDAA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PHZ5-1", "uniprot_id": "RB15B_MOUSE", "id": "Q6PHZ5-1", "name": "Putative RNA-binding protein 15B", "aln": "MKRQSERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGTKHPVPARARDKPRGSGG-GGGHRD--GRAAGDANHR--------ASGGRSSG-APGGGGRTGKASGDPGAGGAS------PRASPLP---------PPPPPPGAEP-----------AGPGS-TAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRFG-----EISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGG----SSRRSSSSSAAASTPPPGPPAPADPLGYLP-LHGGYQYKQRSLSPVAAPPLREPRARHAAAAFALD-AAAAAAVGLSRER--ALDYYGLYDDRGRPYGYQAVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLTDGYTRHRNLDADLRVRDRTPPHLLYSDRDRTFLEGDWTSLSKSSDRRNSLEGYSRSVRSRSGERWGGDGDRSIAKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGGGQQSERGSDRTPERSRKENHSSE-GTKESGSNSLSNSRHGAEERSHHHHHHEAPDSSHGKKTRESERNHRTTEAEPKTLEEPKHETKKLKTLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVISGLLKDHPSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLAIQSTPSGPGAEG-MPVVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDNTGMLYAFPPCDFSQQYLQSALRTLGKLEEEHMVIVIVRDTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F6RM04-1", "uniprot_id": "F6RM04_BOVIN", "id": "F6RM04-1", "name": "Putative RNA-binding protein 15B", "aln": "MKRQSERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPTRARDKPRGSGGSGGGHRD--GRGAGDANHR--------ASSGRSSGSGAGGGGRGGKASGDPGASGAS------PRASPLP---------PPPPPPGAEP-----------TGPGSSAAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRFG-----EISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGGGGGGSSRRSSSSSAAASTPPPGPPAPADPLGYLP-LHGGYQYKQRSLSPVAAPPLREPRARHAAAAFALDAAAAAAAVGLSRER--ALDYYGLYDDRGRPYGYPAVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVGMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLPDGYTRHRNLDADLRVRDRTPPHLLYSDRERTFLEGDWTSPSKSSDRRNSLEGYSRSVRSRSGERWGGDGDRGLPKAWEDRRKRRSLSSDRGRATHSPYEERSRTKGGGQPADRGSDRTPERSRKENHSSE-GTKESGSNSLSNSRHGAEER-SHHHHHEAPDSSHGKKTRESERNHRTTEAEPKPLEEPKHETKKLKNLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVISSLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLATQATPSGPGSEG-MPTVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDSTGMLYAFPPCDFSQQYLQSALRTLGKLEEEHMVIVIVRDTA", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1SIZ8-1", "uniprot_id": "F1SIZ8_PIG", "id": "F1SIZ8-1", "name": "Putative RNA-binding protein 15B", "aln": "MKRQSERDSSPGGRGSSSSAKRPREREREAEAGGRRAAHKASGGTKHPVPTRAREKPRGSGGGGGGHRD--GRGAGDANHR--------ASSGRASGSGAGGGGRGGKASGDPGASGAS------PRASPLP---------PPPPPPGSEP-----------AGPGSSAAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRFG-----EISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGGGGGGSSRRSSSSSAAASTPPPGPPAPADPLGYLP-LHGGYQYKQRSLSPVAAPPLREPRARHAAAAFALD-AAAAAAVGLSRER--ALDYYGLYDDRGRPYGYPAVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLPDGYTRHRNLDADLRVRDRTPPHLLYSDRDRTFLEGDWTSPSKSSDRRNSLEGYSRSVRSRSGERWGGDGDRGLPKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGGGQQADRGSDRTPERSRKENHSSE-GTKELSGNSLSNSRHGAEER-SHHHHHEAPDSSHGKKTRESERNHRTTEAETKPLEEPKHETKKLKNLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVISGLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLATQATPSGPGTEG-MPTVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDSTGMLYAFPPCDFSQQYLQSALRTLGKLEEEHMVIVIVRDTA", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q8NDT2-1", "uniprot_id": "RB15B_HUMAN", "id": "Q8NDT2-1", "name": "Putative RNA-binding protein 15B", "aln": "MKRQSERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPARARDKPRGSGSGGGGHRD--GRGTGDANHR--------ASSGRSSGSGAGGGGRGGKASGDPGASGMS------PRASPLP---------PPPPPPGAEP-----------ACPGSSAAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRFG-----EISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGG---GSSRRSSSSSAAASTPPPGPPAPADPLGYLP-LHGGYQYKQRSLSPVAAPPLREPRARHAAAAFALD-AAAAAAVGLSRER--ALDYYGLYDDRGRPYGYPAVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLTDGYTRHRNLDADL-VRDRTPPHLLYSDRDRTFLEGDWTSPSKSSDRRNSLEGYSRSVRSRSGERWGADGDRGLPKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGSGQQSERGSDRTPERSRKENHSSE-GTKESSSNSLSNSRHGAEERGHHHHHHEAADSSHGKKARDSERNHRTTEAEPKPLEEPKHETKKLKNLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVISSLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLATQATPSGLGTEG-MPTVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDGTGMLYAFPPCDFSQQYLQSALRTLGKLEEEHMVIVIVRDTA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V1A818-1", "uniprot_id": "A0A8V1A818_CHICK", "id": "A0A8V1A818-1", "name": "Putative RNA-binding protein 15B", "aln": "MKRGSERDASPPGAGGGRAAAAKRPRERERESSSRRGPHRSSGASRSSRDKSTPGGGGGGGGGGGGSGGSGGGGSGSRSHRGDERAGGADSNHRPAASGSASGARGQAAPSSSSSSSSSSRALGVPKAKALPGAVVAPSLLLAGPPPGAAPSLLLAPLGGSAGLAGEPPGSCEYKTLLVSGLSAALPDQLLEDGLFRLFQRFAGGGAGDISVKLSHTPELGRVAYVNFRHPGDARDARRHARARQLLLYDRPLKVEPVYLRGGR--------------RSRTPPPAP--SPEPLGYLPPLHGAYQYKQRSLSPVTSPLLREPRPRHAHAAAAAF-ALEAAAIGLSRERERALDYYGLYDERGRPYSYPIVAEEDLMPEDDQRATRNLFIGNLDHNVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVVGRNPIKIGYGKANPTTRLWVGGLGPSTSLAALAREFDRFGSIRTIDYVKGDSFAYIQYESLDAAQAACAQMRGFPLGGPERRLRVDFAKAEETRYPQQYQPAPLPVHYELLADGYSRHRSLEQDLRVRDRTPPHLLYSDRDRSFAEADWASPAKNAERRNNLEGYSRSVRSRSGERWASDSDRAVPKLWEERRKRRSLSSDRGRTAHSPYEDRSRTKASG----PALDRSPERARKENHTTESGTEKEQSNSLQNNRHATEEK----PHREASDAPQPKK-RDSERNHRTGESESKAHEEPKSETKKLKNLSEYAQTLQLAWNGLLVLKNSCFPTSMHILEGDLGVINGLLKDHSSGGKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLATQSAPGGAGAEGTFPVVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGAKGRDSTGMLYAFPPCEFSQQYLQSALRTLGKLEEEHMVIVIVKDTA", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** .***:** * *.. :* * **** *:..**..*::**.:: . : *.*. *** . * .:*. .** *. *.:. ....*.* *.....:.. * *:*..** . ****: * .* ..: ******:*.**.*** : *** **: *:**. :**::****************** ***:**:** ********************* : ****.* ..:****** ***.***********::* *****.*** ** * * ***:****** *********:*****.* *.***********************.************************************************.*****:*************************.********************:**********************:*********:*********************:*********.***:***.*: ** **************:*:* *.**:* :*.::***.****************..*.**.:.* **:*************::*****:*****..* . **:***:*****::* **:: .***.*.**.:**: *:**.*:.: ** *:******* *:*.*. **** ******.**********.********************** ***..*****.**.************************************** *::*.* *:** :* ********************************:****.**********:**************************:*:*", "identical_positions": 648, "similar_positions": 146, "identity": "68.86%" }, { "cls_id": "homologset.oma.818869", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "M0R3Z8-1", "uniprot_id": "M0R3Z8_RAT", "id": "M0R3Z8-1", "name": "RNA-binding protein 15", "aln": "MRSAGREPLPRRSPRWRRASPLCETSAGWRVSQLRRDDLRRPSTMKGKERSPVKPKRSRGGEDSSSRGERSKKLGGSGGSNGSSSGKTDSGG-SRRSLHLDKSSSRGGSREYDTGGGSSSSR----LHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGVEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLS-GSGSGDERVAFVNFRRPEDARAAKHARGRLVLYDRPLKIEAVYVS-------RRRSRSP--LDKDT-YAPSSSVVGSSVGSHRHAPGGGGG-QRSLSPGG--AALGYRDYRLQQLALGRLPPPPPPPLPRELERERDYP-FYDR-VRPAYSLEPRVGAGAGAAPFR---------EVDEISPEDDQRANRTLFLGNLDITVTENDLRRAFDRFGVITEVDIKRPSRGQTSTYGFLKFENLDMSHRAKIAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTIRTIDYRKGDSWAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQYLQPLPLT---HYELVTDTFG---HR--APDPLRSARDRTPPLLYRDRDRDLYPDSDWVPPPPPVRERSARAATSAVTAYEPLDSLDR--RRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDR--PRKQRHCTPS---PDRSPELSSNRDRYNSDNDR-SSRLLLLERPSPVRD-RRGSLEKSQSDKRDRKNSASAERDRKHRTAAPT---EGKTPLKKEDRSDGNTPSASTSSSKQKPPSQKQDGGTAPVAASSPKLCLAWQGMLLLKNSNFPSNMHLLQGDLQVASSLLVEGSTGGKVAQLKITQRLRLDQPKLDEVTRRIKVAGPNGYAILLAVPGSSDSRSSSSSATSDTAASTQRPLRNLVSYLKQKQAAGVISLPVGGNKDKENTGVLHAFPPCEFSQQFLDSPAKALAKS--EEDYLVMIIVR-------AKLVNIG---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0VBL3-1", "uniprot_id": "RBM15_MOUSE", "id": "Q0VBL3-1", "name": "RNA-binding protein 15", "aln": "MRSAGREPLPRRSPRWRRASPLCETSAGWRVSQLRRDDLRRPSTMKGKERSPVKPKRSRGGEDSSSRGERSKKLGGSGGSNGSSSGKTDSGG-SRRSLHLDKSSSRGGSREYETGGGSSSSR----LHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGVEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLS-GSGSGDERVAFVNFRRPEDARAAKHARGRLVLYDRPLKIEAVYVS-------RRRSRSP--LDKDA-YAPSSSVVGTSVGSHRHAPGGGGG-QRSLSPGG--AALGYRDYRLQQLALGRLPPPPPPPLPRELERERDYP-FYDR-VRPAYSLEPRVGAGAGAAPFR---------EVDEISPEDDQRANRTLFLGNLDITVTENDLRRAFDRFGVITEVDIKRPSRGQTSTYGFLKFENLDMSHRAKLAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTIRTIDYRKGDSWAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQYLQPLPLT---HYELVTDTFG---HR--APDPLRSARDRTPPLLYRDRDRDLYTDSDWVPPPPPVRERSARAATSAVTAYEPLDSLDR--RRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESER--PRKQRHCTPS---PDRSPELSSNRDRYNSDNDR-SSRLLLLERSSPVRD-RRGSLEKSQSDKRDRKNSASAERDRKHRTAAPT---EGKNPLKKEDRSDGNAPSASTSSSKQKPPSQKQDGGTAPVAASSPKLCLAWQGMLLLKNSNFPSNMHLLQGDLQVASSLLVEGSTGGKVAQLKITQRLRLDQPKLDEVTRRIKVAGPNGYAILLAVPGSSDSRSSSSSATSDTAASTQRPLRNLVSYLKQKQAAGVISLPVGGNKDKENTGVLHAFPPCEFSQQFLDSPAKALAKS--EEDYLVMIIVR-------AKLVNSG---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8C2L987-1", "uniprot_id": "A0A8C2L987_CRIGR", "id": "A0A8C2L987-1", "name": "RNA-binding protein 15", "aln": "MRSAGREPLPRRSPRWRRASPLCETSAGWRVSQLRRDDLRRPSTMKGKERSPVKPKRSRGGEDSSSRGERSKKLGGSGGSNGSSSGKTDSGG-SRRSLHLDKSSSRGGSREYDTGGGSSSSR----LHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGVEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLS-GSGSGDERVAFVNFRRPEDARAAKHARGRLVLYDRPLKIEAVYVS-------RRRSRSP--LDKDT-YPPSSSVVGTSVGSHRHAPGGGGG-QRSLSPGG--AALGYRDYRLQQLALGRLPPPPPPPLPRELERERDYP-FYDR-VRPAYSLEPRVGAGAGAAPFR---------EVDEISPEDDQRANRTLFLGNLDITVTENDLRRAFDRFGVITEVDIKRPSRGQTSTYGFLKFENLDMSHRAKLAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTIRTIDYRKGDSWAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQYLQPLPLT---HYELVTDTFG---HR--APDPLRSARDRTPPLLYRDRDRDLYTDSDWVPPPPPVRERSARAAASAVTAYEPLDSLDR--RRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDR--PRK-RHCTPS---PDRSPELSSNRDRYNSDNDR-SSR-LLLERPSPIRD-RRGSLEKSQSDKRDRKNSASAERDRKHRTAAPT---EGKNPLKKEERSDGNAPSASASSSKQKAPSQKQDGGTAPVAASSPKLCLAWQGMLLLKNSNFPSNMHLLQGDLQVASSLLVEGSTGGKVAQLKITQRLRLDQPKLDEVTRRIKVAGPNGYAILLAVPGSSDSRSSSSSATSDTATSTQRPLRNLVSYLKQKQAAGVISLPVGGNKDKENTGVLHAFPPCEFSQQFLDSPAKALAKS--EEDYLVMIIVR-------AKLVNSG---------", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q96T37-1", "uniprot_id": "RBM15_HUMAN", "id": "Q96T37-1", "name": "RNA-binding protein 15", "aln": "MRTAGRDPVPRRSPRWRRAVPLCETSAGRRVTQLRGDDLRRPATMKGKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSR----LHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLS-GSGSGDERVAFVNFRRPEDARAAKHARGRLVLYDRPLKIEAVYVS-------RRRSRSP--LDKDT-YPPSASVVGASVGGHRHPPGGGGG-QRSLSPGG--AALGYRDYRLQQLALGRLPPPPPPPLPRDLERERDYP-FYER-VRPAYSLEPRVGAGAGAAPFR---------EVDEISPEDDQRANRTLFLGNLDITVTESDLRRAFDRFGVITEVDIKRPSRGQTSTYGFLKFENLDMSHRAKLAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTIRTIDYRKGDSWAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQYLQPLPLT---HYELVTDAFG---HR--APDPLRGARDRTPPLLYRDRDRDLYPDSDWVPPPPPVRERSTRTAATSVPAYEPLDSLDR--RRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDR--PRK-RHCAPS---PDRSPELSSSRDRYNSDNDR-SSR-LLLERPSPIRD-RRGSLEKSQGDKRDRKNSASAERDRKHRTTAPT---EGKSPLKKEDRSDGSAPSTSTASSKLKSPSQKQDGGTAPVASASPKLCLAWQGMLLLKNSNFPSNMHLLQGDLQVASSLLVEGSTGGKVAQLKITQRLRLDQPKLDEVTRRIKVAGPNGYAILLAVPGSSDSRSSSSSAASDTATSTQRPLRNLVSYLKQKQAAGVISLPVGGNKDKENTGVLHAFPPCEFSQQFLDSPAKALAKS--EEDYLVMIIVRGFGFQIGVRYENKKRENLALTLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1S619-1", "uniprot_id": "F1S619_PIG", "id": "F1S619-1", "name": "RNA-binding protein 15", "aln": "MKTAGRDPLPRRSPRWRRAVPLCETSAGRRVNQLRGEDLRRPATMKGKERSPVKPKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYETGGGSSSSR----LHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGGEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLS-GSGSGDERVAFVNFRRPEDARAAKHARGRLVLYDRPLKIEAVYVS-------RRRSRSP--LDKDS-YPPSASVVGSSVGGHRHPPGGGGGGQRSLSPGG--AALGYRDYRLQQLALGRLPPPPPPPLPRELERERDYP-FYER-VRPAYSLEPRVGAGAGAAPFR---------DVDEISPEDDQRANRTLFLGNLDITVTESDLRRAFDRFGVITEVDIKRPSRGQTSTYGFLKFENLDMSHRAKLAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTIRTIDYRKGDSWAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQYLQPLPLT---HYELVTDAFG---HR--APDPLRGARDRTPPLLYRDRDRDLYPDSDWVPPPPPVRERSTRTAATAVPAYEPLDSLDR--RRDGWSLDRDRGERDLPSSRDQPRKRRLPEESGGRHLDRSPENDR--PRK-RHCAPS---PDRSPELSSSRDRYNSDNDR-SSRLLLLERPSPVRD-RRGSLEKSQGDKRDRKNSASAERDRKHRTTAST---EGKSPLKKEDRSDGSAPSTSTASSKLKSPSQKQDGGTAPAAAASPKLCLAWQGMLLLKNSNFPSNMHLLQGDLQVASSLLVEGSTGGKVAQLKITQRLRLDQPKLDEVTRRIKVAGPNGYAILLAVPGNSDSRSSSSSATSDTATSTQRPLRNLVSYLKQKQAAGVISLPVGGNKDKENTGVLHAFPPCEFSQQFLDSPAKALAKS--EEDYLVMIIVR-------AKLVNNG---------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A8V1ABA2-1", "uniprot_id": "A0A8V1ABA2_CHICK", "id": "A0A8V1ABA2-1", "name": "RNA-binding protein 15", "aln": "MK--GKERSPAKAKRSRGGG--------------GGEDSASSSSSARGERSSKKPSGSGGG-----GGSNGGKAAAAAASNDSNSGS------SRRGPHPDK-AARAGSREYESGAAAAATGGGGGRHSYGGKSAEPSRS-----SSSRGGESRAAVAAQSSSSSETGGGGEYKTLKISELGSALSDEAVEDGLFHEFKRFGDVSVKISRLPPGTGAADERVAFVNFRRPEDARAAKHARGRLVLYDRPLKIEAVYVGSGGGSSRRRSSRSPALLDKESPYGTAAVGLAAAAAAVRHP--AAGATQRALSPAGSGGALGYRDYRLQQLALGRLPPPPP--LPRELERERDYGGFYEARVRPAYGLE-RVASVAAAGGFRGGGGGAGAAGEEEISPEDDQRANRTLFLGNLDITVSETDLRRAFDRFGVITEVDIKRPGRGQTSTYGFLKFENLDMAHRAKLAMSGKVLLRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTIRTIDYRKGDSWAYIQYESLDAAQAACTHMRGFPLGGPDRRLRVDFADTEHRYQQPYLQPLPLPPPAHYELVAEAAAFGAHRGAPPDPLRGARDRTPPLLYRDRDRDLYPETEWVPPPPPVRDRSNRAAA-----YDPLESLER--RRDGWSLERDRGERELGSSRDQPRKRRLAED-GGRHLDRSPDSERSSSSRKRHCLTTTTPPDRSPELVGGRERYSSDPERSSSRLLLLERPSPIRESRRGSLERGQNEKRDRKN--SAERERKHRTSAAATAQECKSPAKKDER----AAEGGGGGSRLKPPPQKQQQDGASQAGGAPKLCLAWQGMLLLKNSNFPSNMHLLQGDLGVASSLLVEGATGGKVAQLKITQRLRLDQPKLDEVNRRIKVAGPNGYAILLAVPGTSDNRSAAG-AGEAATTSTQRPLRNLVSYLKQKQAAGVISLPVGGNKDKENSGVLHAFPPCDFSQQFLDSTAKALAKS--EDDYLVMIIVRG------AS--------------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "F1RCY7-1", "uniprot_id": "F1RCY7_DANRE", "id": "F1RCY7-1", "name": "RNA-binding protein 15", "aln": "MK--GKERSPVK-----------------------------------KRSRALDDIRDRGGSHPTSKKMGVISNSGGGSNNGNSSSKSDGGS-ARRGLLGDK---RDG-REFDGHVSSRTGN----NHGYTSPVASSSGK---NHASSLSLEAARTNSRGEARAPLPTNESEYKTLKISELGSQLSDEEIEDGLFHEFKKFGDVSVKISRVN------DERIAFVNFRRPDDARAAKHARGRLVLYDRPLKIEAVYLN-------RRRSRSP--VKEDH---------FSVVAGHRHLH-----TQRPLSPTG----LGYRDYRLQQLALGRLPPPPPPPLPRELEREREFA-FYEARARPAYIAE-------RAAPFR---------EEDFISPEDDQRANRTLFLGNLDITVTENDLRRAFERFGTITEVDIKRPTRGQSSTYGFLKFENLDMAHRAKISMSGKVVGRNPIKIGYGKATPTTRLWVGGLGPWVPLTALAREFDRFGTIRTIDYRKGDTWAYIQYESLDAAQAACTHMRGFPLGGPDRRLRVDFADTEHRYQQQFLQPLPLQ---HYEIMAESFV---HR-ATPEAIR-VRERTPPPLH-FRERELYAGAEWPAP--TIRERVRTP------AFEPLEHLERERRREAWSLER-----ELPG-REAARKRRLMED--GRHLECSPDSSSEWAAR-RRRPPS---LEGSPGGSS-RDGRFSDSER-PAR---ADRVSPARE-SRSSLDRVPGEKRIKSNSNLSESS------------IGASPAERKRK----AGDSAKGASKRDRSESSSKSNQASKQDAGGKLSMAWNGMLLLKNSNFPASMHLLEGDLSVATSLLIDGSTGGKVSQLRITQRLRLDQPKIDEVSRRIKVAGPGGYAVLLAVPGSSEETSSSD-----PAASTQRPLRNLVSYLKQKQAAGVISLPVGGSRDKDNTGVLHAFPPCDFSQQFLDSSAKALAKT--EEDFLVMIVVRG------AS--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KMJ6-1", "uniprot_id": "NITO_DROME", "id": "Q7KMJ6-1", "name": "RNA-binding protein spenito", "aln": "----------------------------------------------------MSSHRDGAGADRITIKIHNMKRSASRSPGPASRSSLSRNS-------------RSMGRGYDNGSGVPGDS----------PERLSPERMRRRLDRSPSRYGSPHREPYMRGPPPAERPAGYKVLCVSALPPKAPDDFIEETLYREYKKFGDFSVRLAHDL------DERVAYVCFRTPEDAREAKHHKPRLIIYDKMAIVEPVYKSTTRPEYRPRGHSMSPPDYERYHYSRSPMGQGVPLDHRRPPIDPYDRYGPPHMHPHAVHPRDYRPLHHDYPHPPRGPPLHRGGHPHHLHGHAPPHQYAPMRPLAPRPHAPYEKPESKKDKFPN--------YLHHVQPEDDPLSTRTLFAGNLEVTIADDELRRIFGKYGVVDDIDIKRPPPGTGNAFAFVRYQNLDMAHRAKIELSGQYIGKFQCKIGYGKVTPATRMWIGGLGAWTSVTQLEREFDRFGAIKKIEYQKGEPYAYIQYETVEAATAAVKEMRGFPLGGPERRLRTDFAELPGATPAAPFKSSKPP----YDESALEYR-----------------RPEYDPYYEESAAYAPRGGYSPYPPRGGYR----------------------GRGGYRGRGRGMYHYHNDVHRPPHPGSLAGSSSSVPPPGGVEDEWR----------------RPPGESYDRGARSSSREP-----------GVERSRSRSPLKRAR---------------------------------------------SPGSDSDTSTRRNDALASASTVPDVARKCSTVWTGALILKSSLFPAKFHLTDGDTDIVESLMRDEEGK---HNLRITQRLRLDPPKLDDVQKRIASS--SSHAIFMGLAGSTNDTNCDD------ASVQTRPLRNLVSYLKQKEAAGVISLLN---KETEATGVLYAFPPCDFSTELLKRTCHSLTEEGLKEDHLVIVVVRG------GTA-------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .* . ... . . . .. * * :: . . * . . .. **.* :* * . .*: :*: *::*:*:***.**:::: ***:*:* ** *:*** *** : **::**: :*.** . * . : * . .** : : * ** *:.*. . : .. * . :.**** :.**** ***::*::: :*** * ::*.: ::***** * .::.*::::****:****: :**: : : ******.**:**:*:****.*..:: * *******:*:.*:*:**:.:******:::** ** ..*********:****.***: ::. *: : *. : .. . : . * * .: . : .: * . . . :.. .* * *. : . *. *..*.: . * . .. . :. . * . .* * *:**.* **:.:** :** :. **: : :*:******** **:*:* :** : ..:*:::.:.*.::. .. . :: *************:******* ::.: :***:*****:** ::*. ..::*:: ::*.**:::** ", "identical_positions": 220, "similar_positions": 215, "identity": "21.36%" }, { "cls_id": "homologset.oma.818978", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQ56-1", "uniprot_id": "D3ZQ56_RAT", "id": "D3ZQ56-1", "name": "DNA-directed RNA polymerase III subunit RPC6", "aln": "MGAPSRPHEEGPARPKEEGPSSLPRPHPWRAPPPVPENSSALLRATFPLVLKTTLMAEVKVKVQPPDADPVEIENRIIELCHQFPHGITDQVIQNEMPHIEAQQRAVAINRLLSMGQLDLLRSNTGLLYRIKDSQNAG-------KMKGSDNQEKLVYQIIEDAGNKGIWSRDIRYKSNLPLTEINKILKNLESKKLIKAVKSVAASKKKVYMLYNLQPDRSVTGGAWYSDQDFESEFVEVLNQQCFKFLQSKAETARESKQNPVIQRNSSFASSHEVWKYICELGISKVELSMEDIETILNTLIYDGKVDMTIIAAKEGTVGSVDGHMKLYRAVNPILPPTGLVRAPCGLCPVFDDCHEGGEISPSNCIYMTEWLEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q921X6-1", "uniprot_id": "RPC6_MOUSE", "id": "Q921X6-1", "name": "DNA-directed RNA polymerase III subunit RPC6", "aln": "-------------------------------------------------------MAEVKVKVQPPDADPVEIENRIIELCHQFPHGITDQVIQNEMPHIEAQQRAVAINRLLSMGQLDLLRSNTGLLYRIKDSQNAG-------KMKGSDNQEKLVYQIIEDAGNKGIWSRDIRYKSNLPLTEINKILKNLESKKLIKAVKSVAASKKKVYMLYNLQPDRSVTGGAWYSDQDFESEFVEVLNQQCFKFLQSKAETARESKQNPVIQRNSSFASSHEVWKYICELGISKVELSMEDIETILNTLIYDGKVEMTIIAAKEGTVGSVDGHMKLYRAVNPILPPTGVVRAPCGLCPVFEDCHEGGEISPSNCIYMTEWLEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1D9-1", "uniprot_id": "RPC6_HUMAN", "id": "Q9H1D9-1", "name": "DNA-directed RNA polymerase III subunit RPC6", "aln": "-------------------------------------------------------MAEVKVKVQPPDADPVEIENRIIELCHQFPHGITDQVIQNEMPHIEAQQRAVAINRLLSMGQLDLLRSNTGLLYRIKDSQNAG-------KMKGSDNQEKLVYQIIEDAGNKGIWSRDIRYKSNLPLTEINKILKNLESKKLIKAVKSVAASKKKVYMLYNLQPDRSVTGGAWYSDQDFESEFVEVLNQQCFKFLQSKAETARESKQNPMIQRNSSFASSHEVWKYICELGISKVELSMEDIETILNTLIYDGKVEMTIIAAKEGTVGSVDGHMKLYRAVNPIIPPTGLVRAPCGLCPVFDDCHEGGEISPSNCIYMTEWLEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AAA9S0Z5-1", "uniprot_id": "A0AAA9S0Z5_BOVIN", "id": "A0AAA9S0Z5-1", "name": "DNA-directed RNA polymerase III subunit RPC6", "aln": "-------------------------------------------------------MAEVKVKVQPPDADPVEIENRIIELCHQFPHGITDQVIQNEMPHIEAQQRAVAINRLLSMGQLDLLRSNTGLLYRIKDSQNAGPVSFFLSKMKGSDNQEKLVYQIIEDAGNKGIWSRDIRYKSNLPLTEINKILKNLESKKLIKAVKSVAASKKKVYMLYNLQPDRSVTGGAWYSDQDFESEFVEVLNQQCFKFLQTKAETARESKQNPMIQRNSSFASSHEVWKYICELGISKVELSMEDIETILNTLIYDGKVEMTIIAAKEGTVGSVDGHMKLYRAVSPIIPPTGLVRAPCGLCPVFDDCHEGGEISPSNCIYMTEWLEF", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1SBH4-1", "uniprot_id": "F1SBH4_PIG", "id": "F1SBH4-1", "name": "DNA-directed RNA polymerase III subunit RPC6", "aln": "-------------------------------------------------------MAEVKVKVQPPDADPVEIENRIIELCHQFPHGITDQVIQNEMPHIEAQQRAVAINRLLSMGQLDLLRSNTGLLYRIKDSQNAG-------KMKGSDNQEKLVYQIIEDAGNKGIWSRDIRYKSNLPLTEINKILKNLESKKLIKAVKSVAASKKKVYMLYNLQPDRSVTGGAWYSDQDFESEFVEVLNQQCFKFLQTKAETARESKQNPVIQRNSSFASSHEVWKYICELGISKVELSMEDIETILNTLIYDGKVEMTIIAAKEGTVGSVDGHMKLYRAVNPIISPTGLVRAPCGLCPVFDDCHEGGEISPSNCIYMTEWLEF", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A8C2LHN4-1", "uniprot_id": "A0A8C2LHN4_CRIGR", "id": "A0A8C2LHN4-1", "name": "DNA-directed RNA polymerase III subunit RPC6", "aln": "-------------------------------------------------------MAEVKVKVQPPDADPVEIENRIIELCHQFPHGITDQVIQNEMPHIEAQQRAVAINRLLSMGQLDLLRSNTGLLYRIKETQNAG-------KMKGSDNQEKLVYQIIEDAGNKGIWSRDIRYKSNLPLTEINKILKNLESKKLIKAVKSVAASKKKVYMLYNLQPDRSVTGGAWYSDQDFESEFVEVLNQQCFKFLQTKAETARESKQNPMIQRNSSFASSHEVWKYICELGISKVELSMEDIETILNTLIYDGKVEMTIIAAKEGTVGSVDGHMKLYRAVNPILPPTGLVRAPCGLCPVFDDCHEGGEISPSNCIYMTEWLEF", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q9VD25-1", "uniprot_id": "RPC6_DROME", "id": "Q9VD25-1", "name": "DNA-directed RNA polymerase III subunit RPC6", "aln": "--------------------------------------------------------------------MATEVSQLLLAVVQGIPAGATNDDLTKALPDVPAATRVEALNILLQEGGIEILKKGEKLVYRAKDPEKKS------ALPKDADNEEKVVYGIVEEGGNKGIWIRDIRMKSNLNMIQLNKILKNLETKKLIKAVKSVNASKKKVYMLYNLEPDLSITGGAWYQDQDFEVEFVDVLNQQCLRFLQMKRDSAEKKREGPLAFKQMSCCTVNEVQKFISDLGISKVNLAEADLETILKTVVYDGNAER--VRQQDGSF--------VYRAVNAPLPPTGLVQMPCGICPVIKNCSNCGDVTAITCEYMRDWLD-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9LSZ5-1", "uniprot_id": "Q9LSZ5_ARATH", "id": "Q9LSZ5-1", "name": "DNA-directed RNA polymerase III subunit RPC6", "aln": "-----------------------------------------------------------------------------------------------------------------------MSKR------KRPDPKSSG--------GDLNEPHEKKLLDLIRINQGRGATMFELKREKTIPATIVTRLIASLRKKNLIKEVANMNNKGVKHYLAMEFEPCSELTGGEWYTDGALDLSKIEDLKAKCVMILERHRQRVVTLEVLCGYFVKEEKLSVDQTKEILKNLILDNLIMEVKSNGMNEFASTRIGEVCYRLTGKK---------------FGNGEPRAGAFASIPCGVCPHIAICSPDGVISPTTCVYFQKWLDF", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :.:. . . : .** : ::. .:* ::: :..: :.::: .*..*:*** * .: . * *: :::* .:*** ** * :: . :: *: :*. :*: : : . . : . : .:. : : :* :.:: : . : *:. : . . ... ***:** : * * ::. .* *: .**: ", "identical_positions": 34, "similar_positions": 89, "identity": "8.99%" }, { "cls_id": "homologset.oma.819406", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7J4-1", "uniprot_id": "D4A7J4_RAT", "id": "D4A7J4-1", "name": "Mediator of RNA polymerase II transcription subunit 31", "aln": "MAAAVAMETDDAGNRLRFQLELEFVQCLANPNYLNFLAQRGYFKDKAFVNYLKYLLYWKEPEYAKYLKYPQCLHMLELLQYEHFRKELVNAQCAKFIDEQQILHWQHYSRKRMRLQQALAEQQQQN--------TTAGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CXU1-1", "uniprot_id": "MED31_MOUSE", "id": "Q9CXU1-1", "name": "Mediator of RNA polymerase II transcription subunit 31", "aln": "MAAAVAMETDDAGNRLRFQLELEFVQCLANPNYLNFLAQRGYFKDKAFVNYLKYLLYWKEPEYAKYLKYPQCLHMLELLQYEHFRKELVNAQCAKFIDEQQILHWQHYSRKRVRLQQALAEQQQQN--------NTAGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3C7-1", "uniprot_id": "MED31_HUMAN", "id": "Q9Y3C7-1", "name": "Mediator of RNA polymerase II transcription subunit 31", "aln": "MAAAVAMETDDAGNRLRFQLELEFVQCLANPNYLNFLAQRGYFKDKAFVNYLKYLLYWKDPEYAKYLKYPQCLHMLELLQYEHFRKELVNAQCAKFIDEQQILHWQHYSRKRMRLQQALAEQQQQN--------NTSGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A4X1UL35-1", "uniprot_id": "A0A4X1UL35_PIG", "id": "A0A4X1UL35-1", "name": "Mediator of RNA polymerase II transcription subunit 31", "aln": "MAAAVAMETDDAGNRLRFQLELEFVQCLANPNYLNFLAQRGYFKDKAFVNYLKYLLYWKEPEYAKYLKYPQCLHMLELLQYEHFRKELVNAQCAKFIDEQQILHWQHYSRKRMRLQQALAEQQQQN--------NTSGK", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0JNN3-1", "uniprot_id": "MED31_BOVIN", "id": "A0JNN3-1", "name": "Mediator of RNA polymerase II transcription subunit 31", "aln": "MAAAVAMETDDAGNRLRFQLELEFVQCLANPNYLNFLAQRGYFKDKAFVNYLKYLLYWKEPEYAKYLKYPQCLHMLELLQYEHFRKELVNAQCAKFIDEQQILHWQHYSRKRMRLQQALAEQQQQN--------NASGK", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q6DH26-1", "uniprot_id": "MED31_DANRE", "id": "Q6DH26-1", "name": "Mediator of RNA polymerase II transcription subunit 31", "aln": "MAG--VMETDEQA-RQRFQLELEFVQCLANPNYLNFLAQRGYLREKPFVNYLKYLLYWKEPEYAKFLKYPHCLHMLELLQYEHFRKELVNAQCAKFIDEQQILHWQHYSRKRTRLQQALAEQQQQQQPQAPSHANTTSK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. .****: . * **************************:::*.************:*****:****:***************************************** ************: .::.*", "identical_positions": 109, "similar_positions": 16, "identity": "78.42%" }, { "cls_id": "homologset.oma.819451", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U5X0-1", "uniprot_id": "LYRM7_HUMAN", "id": "Q5U5X0-1", "name": "Complex III assembly factor LYRM7", "aln": "MGRAVKVLQLFKTLHRTRQQVFKNDARALEAARIKINEEFKNNKSETSSKKIEELMKIGSDVELLLRTSVIQGIHTDHNTLKLVPRKDLLVENVPYCDAPTQKQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A287ADQ4-1", "uniprot_id": "A0A287ADQ4_PIG", "id": "A0A287ADQ4-1", "name": "Complex III assembly factor LYRM7", "aln": "MGQAAKVLRLFKTLHRTRQQVFKNDARALEAARIKINEEFKCNKSETSPKKIEELIKIGSDVELILRTSVIQGIHTDHNTLKLVPRKDLLIENVPYCDAPTQKQ", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "B4F7A1-1", "uniprot_id": "LYRM7_RAT", "id": "B4F7A1-1", "name": "Complex III assembly factor LYRM7", "aln": "MGQPAKVLQLFKTLHRTRQQVFKNDKRALEAARVKINEEFKKHKNETSPEKIKEMLKIGSDVELLLRTSVIQGIHTDHDTLQLVPRKDLLTENVPYCDAPTQKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DA03-1", "uniprot_id": "LYRM7_MOUSE", "id": "Q9DA03-1", "name": "Complex III assembly factor LYRM7", "aln": "MGQPAKVLQLFKTLHRTRQQVFKNDKRALEAARVKINEEFKKHKNETSPEKIKEMMKLGSDVELLLRTAVIQGIHTDHDTLQLVPRKDLLTENVPYCDAPTQKQ", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:..***:**************** *******:******* :*.***.:**:*::*:******:***:*********:**:******** ************ ", "identical_positions": 83, "similar_positions": 17, "identity": "79.81%" }, { "cls_id": "homologset.oma.820094", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C6S9-1", "uniprot_id": "CFA54_MOUSE", "id": "Q8C6S9-1", "name": "Cilia- and flagella-associated protein 54", "aln": "MASSRSSSSSSEESPDSETSVSPVHLPPTPPPTSTAVLKSPSESKSSS-TDPPQCTHSEDSLPSAAFYGPLDSKNPLLASCEKEIRELLGFMKKKKALATSMEQKYEFHRRCATTLFNIWTKYAPRLPSNYYNEKLLKVGDSLCQIKEYKLALLQCYGRYLQEFIA--DFDEHKEDVNHFKTVFFPKGFGDETARLTFHALSGKNICNYQLVCESDANLQNEESVRQCLHILSSFRLIMQVALPQEHLCWIIFNGTLYIYTICRKLMVIGQSSKALEFLLWASMCMESSVPLLSIRYLTWRATLYTAVCQCHYDCQDGIHGEAFARRALAKIDELRQLELMSSSSSLETSRKYYREATIKMAVMIFKRGVFESRRKNKNVLRPKLRLNLKEAQSLPWPRTVTERLLDELLDSTSSRFLAVLEALSDSNRRILQTGPLVTDEMELRDVVSELFMAGKELLILSNVRSNGKLD---------FPQTSLLEHVVEKRNALSVGASVRFAKLAFTYEEWGLFESLAGQLIHFLQKQDNPQSKKAEKDLILLLAVEPLINVKRNRGLIFPLETDKETQSIENYLKHIACHESCMRTT-FTEDTFSLAAILHFCVCVPTQGVLPDKDIVVDIIGLLWQRCKLGIQRLNIPKNDFAKYSHKISTNKWVYLLWQISEVIHCYKLEDLDIVMVAEITLRLSEILESLGSPKRKFKKSADLSAKKGPDELPGTSKGVPEILPILKRAPVEQLFYAYELLDKAIIGMSWKCMLTTLSDGSSVIDHCYVKDSQD-------VDGDTYKPIASNSYTMDLHLELIQAQHRIAVVLLDQLEVLQAPTVSTNTPAKGWEKVKKPRSTECFTELTVMKKIKKNKLSKAIYLMQKALLLFEKDAVCETSRNLLMEANALIEKVEAEQNALYSYQKFLGSSKIKKSRIPPPPILLARTHCSVTLKPAPFISEVKASWYCILGCKADGSYGKVRLNNNHLPNSGEAIPADGRSFFEIKGLETNAQYCFAIAAYSSSGKLIGDAIGETTKPILIYPPLSAVTARMYLTQVAYQIGNYEMAKKVFSPVWDYFVAS--PLPDEQSVICLSNIMTITQKRLHSNILADTSSILLYLFLRNIFVMSDIKIKEENLFCDNIKGNEIFPAQQVARLVECENVLVALELSNFLNDANFALQAVTQCYGLLAPIIYHNIVLVPVIQILIKCIVVLQGIPSIIHSKKNISSFESIQHMIACCIFYMTKILRSWKEYDLAIMLINYGKKMLDITSGCRSLFG--IEQEETAEEGVCSKKTSRTKKPQQVLLPEKINEQLALLETHLLKTTKQINSAELSGSEDPIFLYPIVLNWTVKGAMKEVMKFKQRPRFLEFFTQIMLKCMNDEKFHLMVEISAPVYDFLKRRNESLIGVKRIKYKETVISRRALKSPSKFKAIVIEIGKSSDLTRRRR-----------------KKKKTLKDFFYKNPSIFDMAELDRNKRTDVRKMAYRSLSDNLNPLILTYVRRKRFHQILLEELPWRAQMNLYLANAHFHLFLQKLTERTKERLGSSYSSVSFRSCDPNLFSLFHSGTVLPTAKLTVDSYNAMMDALTVSKKKKHNQTTDTEDLSVLFNS-KSDDNIP-KMKTQTIYESDSQLGIGVNVREKDR--TLVWGLDHFMKIFLCCRRAMVLAYRGGYWTLLQNCCRVFWNFSRELQILLKQTVASCKTFPVSQDNFLCICVLPFYLGAELLIDMLIKLQSTNSIKPFEERGEFSIPSCYGNIKSDNGGSSLIFEHPLDDVNVVDLRWIHDFVLKSLEVLYQVEKWETLVSLAIQFNIISHERYTEQVTPLLVYAQRQLVQRIKELNGPELSRQACARYEAENGEKITCRNFIGKRLKIDSSTPKNLAELQGSSEPLKTLITSEQ-RLAKQLVSVPLDVNDTLRCFRETLEKSKYHNRSVRHSRKLLSLFLAQTQ-----------------------------------------------------------------DVLQTSNQRSLKVQSLHSLGSLLLFADKKRAAFKCWSQALDDIFRKPDVLHNWKEFGTSLPGAPSSSSPPGFKDYSEEFLSKFGIWGCLQAAMITAKIAQFIKTANVKKRINCCILSALLFQSLLRTTLPHPKAERNYAQYEITQLLPGIELFSDKFRADICSVIASLYYVIRELHYAKYNLIVLPLLALYQYFVSVICQDIVRNLEARILKIEILIDLGFFSEAFYELFQIYHGKNMPCAIPAGYKATMKVKITQSFDSGKPLTHKDNMQALEELINRGLPHILVNLGYQHLLNKFNFAKSHFFISLAATINCIPDPSPKIMYYQFITER----SKPTPQN-----LKDNENSHGQFLRLRDDYNLNTIKSILLMEAEEKVNSLLSETEHQCHRPLYLSSVLELEIMVEARLHLAAIALQRYRPAYSTAILYSTLKLLQDSKVFKKKVPEESCS-PTSPETSTTESKDDSEFLDPISLNSREYFNIHLWLRCRLMLVTSFIAQIRGIGIMKESELTDCLSLIDEVCTEAKSADDTEVLAEFLMQAVVLGLQEKHFKADIIQKLKEIISLLEGSEFLSPRSWLTLAKSLILMDDLTKAEKFKK--ASSKENKLIFLNQAHRILIAQMLTFGETIEFPLSDSDYASPLQPLKNIYLPHVMLLAKVKLRIGHTMAKQVCSSSKKKDISKWLPVLHMFDMALKVCKATAAEEYEVEAEILFQKGRIERQMLME-EKTSIAHIESFFEAIQISLKNDQNSGLIRDSYLEIALVYFYLKKPKRKASA--TTLKPLPRRHS---SVKDPVATQTEMYSSLAWIAIRAAAQVSESVLGINLLIGKKRAMIDKVNNITLPNIPEFATVDLLSSYTDYLLENYQVVFQTSNSLMCENDDVYDCIDGRKR---------NLSKVDVTWILLIRYYIHLQRINNMSKLLASATPVSGISLPDDTLLTSLYNSELILRQKEMHLFLKRFLQLYSSSCIDGFPRELLQGLEN-ISLEKVLFESSGKVHRDSSLQSDLSGKLTVCPSYTEIS-SEMAVQALNKELCFQWYIPPLDKPLKDSEPMVLLLYAYNLKPLRILDIKVSTGNSLYVGTSWIPLRSVIAVHQKLSNLAQIAEISLPSVPEVTSEE---------------NIYETIEPEDKPIDTDLENMILECCSEIEALFSNNKDKDNEPPPPMTKVPFDVSLPAIFSLERLFDLANGCIVSVGSLFNWMVSIIQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZKH9-1", "uniprot_id": "A0A8I5ZKH9_RAT", "id": "A0A8I5ZKH9-1", "name": "", "aln": "MASSNNSSSSSEVSPGSETSVSPAQLPPTPPPTSTAVLKSPTESKSSS-TIPPHWTRSEDLLPSAAFYGPLDGKNPLLASCEKEIRELLGFMKKNKALATSEEQKHEFRRRCATTLFNIWTKYAPRLPADYYNEKLLKVGDSLCQIKEYKLALLQCYGRYLQGFTTDFDFDENKEDVNQFKTVFFPNGFGDEMARLTFHALSGKNICNYQLVCQSDANLQNEESVRQCLQILSSFRLIMQVALPQEHLCWIIFNGTLYIYTICRKLMVIGQSSKALEFLLWASMCMESSVPLLSVRYLTWRATLYTAVCQCHYDCQNGIHGETFARRALAKIDELRQLELMSSSSSLETSRKYYREATIKMAVMIFKRGVFESRRKNKNVFRPKIRLNLKEAQSLPWPRTVTERLLDELLDSTSSRFLAVLEALFDSNRRVLQTGPLQTDEMELRDVVSELFMAGKELLLLSNVGANGKLD---------FPKTHLLEQLVERKNIISVGASVKFAKLAFTYEEWGLFESLAGQLIPFLQKQDSPKEKKAEKDLILLLAVEPLINVKKNKGLIFPLDNDKETQSIQSYLKHIAYEESCVRTT-YTEDIFSLAAILHFCVCVPTKGIQPDKDIVVDIITLLWQKCKLGLQRLNIPKSDFTKYSHKISTNKWVYLLWQISEVVHCYKLEDLDIVMVAEITLRLSEILESLGNPKRKFRKSADLSAKKGPDELPGTSKGVPESLPILKRTPVEQLFYAYELLDRTIAGMNWNCMLTTLSDGSSVIDHCYVKDSHD-------VDGDTYKPIASNSYTMDLHLELIQAQHRIAVVLLDQLDALQIPTVSSNSSAKGWEKFKKARSTECFSELTVMKKIKKNTLSKAIYLMQKALLLFEKDTACETSWNLLTEAYALIEKVEAEQNALYSYQKYLESTKVKRSRVPPPPILLARTHCSVTLKPAPFLSDVKVSWYCILGCKAERSYSKVRLNNNHLPNSGEVIPADGRSFFEIKDLETNAKYIFALTAYSSSGKLIGDAIGETTKPILIYPPLSAVTARMYLTQVAYQISNYELAKKVFSPVWDYFVAP--PPQDNQSVICLSNIMTITQRRFHSNILAETSSILLYLFLRNIFVMSDIKIKEENLFCDNIKGNEIFPAQQVARLVECENVLVALELSNFLNDANFALQAVTQCYGLLAPIIYHNIVLVPVIQILIKCIVVLQGIPSVVHSKKNISSFESIQHMIACCIFYITKILRSWKEYDLAIMLINYGKKMLDITSGCKSLFG--IDQEETTEEGTCSKKTSKIKKSQQVLVPEKINEQLTFLETHLLKLTKQITFTELSGAEDPIFLYPVVLNWNVKGAVKEVMKFKQRPRFLEFFTQIMLKCMNDEKFHLMVEICGPVYDFLKRRNESLIGVKRIRYKETTVSRKMLKSPKKFKAIVIEIGRSSDLPRRRR-----------------KRKENLKDFFYKNPSIFDMAELERNKRTDVRKMAYRSLMDNLNPLILTYVKRKRFHQILLEELPWRAQMNLYLANAHFHMFLQKLTERSKIKLGSSHSNVSFRSCDPNLFSLFHSGTILPTAKLTVDSYKAMMDVFSASKKRKHNQPTDIDDLSALFNS-KSDDTVVSKIKAQSTYDSDSQLGSGINIREKDR--MLAWGLDHFVKIFLCCRRAMVLAYRGGYWTLLQNCCRVFWNFSRELQILLKQIMDVCKAFPISQDSFLCISVLPFYLGTELLIDMLIKLQSTNSIKPLEEKGEFSIPSCYGNIKSDNGGSSLTFEHPLDDVNVVDLKWIHDFVLKSLEVLYQVEKWEMLVSLAIQFNTISHERYTEQVTPLLVYAQRQLVLRIEEMEGPDLSHQACARYEAETGEKITCRNFIGKQIMIDRSTPKNLAELDGSSDPLKTLVLSEI-KLAKQLVCVPIDVNDTLRCFRETLEKSNHHSRSVRHSRKLLSLFLAQTQGERGGISSPKFTPGKVEFCLGTEEVHMSTPPDLSQENFRIFSSVEKTKLPSSQLGLVISSFYQTIDVLQASNQRSLKVQTLHSLGSLLIFADKKRAAFKCWSQALDDIFRKPDVLHNWKEFGNSLPSATSSSSPPGFKDYSEEFLSKFGIWGCLQGAVISAKIAQFIKTTNVKERINCCILSALLFQSLLRTTLPHPKAERSYAQYEITQLLPGIELFSDKFRADICIVVASLYYVIRELHYAKYNLIVLPLLALYQYFVSVICQDLVRNLEARILKIEILIDLGLFSEAFYELSQIYQGKNMPCAIPAGYKATTRVKITQSFDSGKPLTSKDNMQALEELVNRGLPSVLVNLGSQHLLNKFNFVKSHFFISLAATVNCIPDNSPKIVYYPVIIDK----SKPNTQN-----AKDNENSHAQLLRFRDDYTLNTIKSILLMEAEDKINSLLSETERQCNRPLYLSSVADLEIMVEARLHLAAIALQRFRPAYSTAIIYCTLKLLQDSKVFKKRLPEEPCS-PTSPETSTTENKDDGEFLDPVSLNCREYFNIHLWLRCRLMLVTSFVAQIRGIGIMKESELTDCLSLINEVCTEAKSADDTEVLAELLMQAVVLGLQEKHFKADIIGKLQEIINLLEGSEFLSPRSWLTLAKSLILMDDLTKAEKFKK--ASSKENKLIFLNQAHRILIAQMLTFGETIEFPLSDADYASPLQPLKNIYLPHIMLLAKIKLRIGHTLAKQVYSSSKKKDIGKWLPVLHVFDMALKVCRATAAEENEVEAEILFQKGRIERQMLME-EKSPIAHVESFFEAIQISLRNDQNPGLLRDSYLEVALVYFYLKKP-RKKTS--VTVKPSPRRLS---SFKEPVATQVEMYSSLAWIAIRAAAQVSESVLAINLLIGKKSTRTDKVNNITLPNIPEFAAADLLSSYTDYLLDNYQVVFQTSVSFACQNEDVYDCIDGRKR---------NLSKVDITWILLIRYYIHLQRINNMSKLLASATPDSGISLPDDTIITSLYNSELILRQKEVHIFLKNFLQLYASSCIDGFPKELLQGLENTISLEKVLFESSDKVHQDSSLQSDLSGKLAGSTSYTDIS-SEMAVQALNKELCFQWYIPPLDKPPKDTEPMVLLLYAYNLKPLVISDIKVPTGNNLYVGTSWIPLRRVIQIHEKLSSLAQIAEISLPSVPEVASQE---------------NIYESIDIEDKPIDTDLENIILHCCSEIEALFSLDKDKK---PLPLTEVPFDVSLPAIFSLERLFDLANGCIVSVGSLFNWVVSIIS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96N23-1", "uniprot_id": "CFA54_HUMAN", "id": "Q96N23-1", "name": "Cilia- and flagella-associated protein 54", "aln": "MAAQGSPSSSP--SDDSTTSGSLPELP----PTSTATSRSPPESKGSSRSSLLQWTCPEDSLPLAVFYGPLDAKNPLLASCEKEIQELLGFMRKKKALATTEEEKHEFRRRCATSLFNIWTKYAPRLPADYYNEKLLKVGDSLCQMKEYKLALLQCYGRYLQQFNT--NFDENKVDVTQFKATFFPKGFKDKTAGLTFHALSGKNMCNYQLVCDSDENLKNKESVVQCLHILSSLRLIMQVALPQEHLCWIIFNGTIYIYTICRKLMVIGQSSKALEYLLWASMCMESLVPLLSLRYLTWRATLYTAVCQCCYDCHAGIHGEAFARRALAKIDELRQLELMSSSKSQEESRRYFREATMKMAVMIFKRGVFESRRKNKAVFRPKIRINLREVQTLSWPRTVTERLLDEMFDSTASQFLAVLEALSDSNRRILQTGPIVTDEVEIHDVVSELFMAGKELLIMSNIGADGMLD---------FPKTSLLELMIGRKDVISVDAAVKFIKLAFTYEEWSLFESSAVHLIYFLQRQDDPESKKAEKDLTLLIAMEPLINVKRNKGLIFPLENYKEGQSTQIYLKKIAVHDTCLKTCGYSEDIFHLAATLYVCVCTAPQDVQPDKEIVVDTIMFLWQKCKLGIQRLNISRNDYAKFTQKISTNKWIYLLWQINEVIHCYKMEDIDIVVVAEVTLRLSEILESLGSPGRKFKQSLDVPLREGTNKFPGAPKGITEILPILQKNPVEQLLFAYKLLDRAIGGINLNCMLTSLPNGSSVIDHCYAKRTHH-------IDGDTYKPLASNSFMMDLHLELIQAQHRIAVVLLDKLQVLQTPTVSKDISTKGPEKLKQSGSTDCFTELNIMNKIKKNTLSKAIYLMQKALLIFEKDATSTSSWELLMEAYSLIQRIEAEQNALYSYQKYLESSKRKKSRVPPPPILLSRTHCSVTLKPAPFTSEVKVSWYCILGCKAEGSYGKVRLNNNHLPNSGEAIPADGKSVFEVKGLETNEKYVFAVAAYSNNGKLVGGAIGETTKPILVYPPLSTITARMFLTQVAYQVGNYELAKKVFSPVWDYFVAS--PLQDEQSVICLSNIITITQRRLHSDILAETSSILLYLFLRNIFVTSDIKIKEENLFCDNIKGNEIFPSQQIARLIECERVLVALELSNFLNDSSYALQAVTQCYGLLAPIIYHNIVLVPVVQILIKCIVVLQGLPSIVCSKKHTASFESIQHMIACCIFYITKILRSWREYDLAVMIINYGKKMLDITPGCKSLFDGSNEQEEMPEE-DSSKKSLKTKKPQQILLPEKINEQLALLETHLLKLTKQYVTSELSGGEDPIFLYPVVLNWSVKGAVKEVMKFKQKPRFLEFFTQVMLKCMNEEKFHLMVEVTTPVHDFLKRRNESLLGLIKVKYKDSALNKKANKS-LKFKAAVMEIGRSAEMQQRIRS----------------KKKETLRDFIFKNPAISEMVAHERNRRTSVRKAAQRYLMDYLNPLILSYVKRKRFHRLSLEEMPWRAQMNLYLAGAHFNLVLQKLWECTKMKFGTSHMMVSFRSCDPNMFSLYNSGTVLPTRKLTVENYKAMLDFLLTAKKRKANLPSDAEEFSTFINSIMSDENMS---KTQTVYDSDSQSGS--SAKEKDRG-ANLCVMDHFMKIFLYCRRAMVLAHRGGYWTLLQNCCRALWNFTQELQILLKQAVDLDKTFPISQDGFLCTSVLPFYLGAELLIDMLIQLQNTSSIKPIEDKGEFSVPSCYGNIKNDNGGSSLTFEHPLDDVNVVDLKWIHDFVLKSLEVLYQVEKWETLVSLAIQFNTVSHERYTEQVTPLLVYAQRQLLLRIQKFKGPDITQQPCARYEAEYGEKITCRNFIGKQLKINSST---IEATSNCTDLLKMLISSEY-SRAKALVCVPVDVTDTLRCFRETLEKSKYHNRSIRHSRKLLSLFLAQTQ-----------------------------------------------------------------DVLQASNQRSLKVQALHSLGSLLIFAEKKRAAFKCWCQALDDIFRKPDVLHTWKEFGPSLTNVTNSHSPPGFKDYSEEFLSRVGIWGCLQGAVISAKIAQFIKSLNVEKKTDCCILSALLFQGLLRTTLPHPKAERCYAQYEITQLLPGIELFSDRYRADICSVIASLYYIIRELHFVRQNLIVLPLLALYQYFVSGICQDITRNLEARILKIEVLIDLRFFSEAFYEISQIFYGKNMPCPIPAGYKATGKMKIFQSFDSGKLLTSKENIQAIDELRNKGLPAVLVTIGQPHLLNKFNFVKAYFFLSVAATINCVPENK----FKTVITNK----SKPNLPNLEEIYSKDDGSSFYNLTKLKDEITLSMLKSMLLMEAEDRLNFLLSEVEQKT---LSQCSAGELEIVVEARLQLAAVALQRHRAAYSAAIVFSTLTLLQDSKLFEKKVVQDDTENPVSPGTSVTENKDDSEFLDPISLNAREYFNIHLWLRCRLALVTAFVAQIHGIGIVKEDDMTDCLSLINEVCMEAKSAGDTELQAEFLTQAVILGLQEKHLKADIMTNLQDIIHLLEGNEFISPQSRLTLARSLVLLDDLTKAEKFKES-PSSKTGKLNLLTRAHSILTEQMLAFGETIEFRSSNTKYANPLQPLKNIYLPHVMLLAKIKMRIGHTVAKQVYYKNKRKDPSKWLPALHLFDVALKLCRTTAVEEHEVEAEILFQKGKIERQILME-EKSPSFQLESLYEAIQLSLKNDQNSGLIRDSYLEMALLYFHLKKPKIKISGSPLTLKPPLRRSS---SVKETSANKFEMYSSLAWIAIRAAAQVSEAVLAINLLIGKKNTRMHKVNQVALPNIPEFAALDLLSSYTDYLLDNYQVLFQTSCTFLYQNDDVCDSADGRKK---------TQTKVDITWILLLRYYIHLQRINNLSKLLASATPVSGISLPDDTLLTSLYNSELILRQKEVHFFLKKFLQLYSSSCIDEFPKELLCQLENPPLSEKDLRESSAKLYRDSSVQSILSFKPVSGSSCVDITPIEMVTQASNKELCFQWYIPPLDRPPKETEPMVLLLYAYNLKPLKISDVRHSTYNSTCVGSLWIPLNRVIAIHEKLSNLAQIAELSLPAAPEITSNE---------------NIYE-VEVEEESVDNEMEDMIIQCCSEIASLFLNDKEPT-----PLSEVPFDISLPSIFNLERLFDLANGCILSGGSLFNWIVSIIP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0YFF9-1", "uniprot_id": "A0A8V0YFF9_CHICK", "id": "A0A8V0YFF9-1", "name": "", "aln": "MAEPAEPPPPAPVPRP------------------------------------------------AAFFGAVAPGNPVVDSLEAELRDVVRFLRRLRGTGEAEPHWHELHRRGANTLFNIWIKYKPRLPDWYYNDKLLKVGDSLAQIKEYKLALTQCYGRYLQQFCS-VNPDDITDDENQFKSTFFPNGFRDKNAALTFHALQERNVCVYQMVCNSDRNLQKQESLQTCFKVLSSLRLTMQMALPQQNLCWLIYNGTIHIYMICRHLMMIGQSAKVLEYLLWASICMELSIPLLSVHYLTWRATLYAAVSQCYFDCQAGIHGEVFARRGLIQINELKQLENISSSQKSSETGKIFREATIKMSVMIFKRAVYESRRKPKSYFRPKLRVNLKEAQNLPWPRTTTEQLLMEMFDGTASQFLAILEALSDSSRRVLHPTPPVPDEPEIRDVISELFFAGLEILSGGVSSTDVQGDDCTDKFGIINASSTLLQLILTGEKRVSGEAAVKFAKLAFNYEEWDVFDSAIVFVTNFLQAQNDPRWKKAEVELKLLTLMKPLLFPRKFRHGFSVSENNTKGDHMPRVSDKKRTVRSSLKCGEPSHDLIILATTVFSYVSTSKQNILPDKEILFDVITFLWQKCKTGLQLIQINGIGNFKYNHKYKASKWVYVLWIINEVILQSNVADTDVVMVAEITLCLTAILENMADSASKSKK------KAGKRSVILSEDDSCDIPEILMRSPTEQLQLAYEYLEKTINEMNKSRLMTFLPDGKSILDDCCTKVDSHGQNLSSVLEWSNDKTRTGNSFLMDLHLELIQAQHRIAVKLLKMTQSVQKDGKSLKSSK---YHVKNNEDSHYLTEADIMGKIKKNKLSRAIFLMEKAVQMFPKDLSTSSQRQLLKEALTLIEQVEAEQSALYHSLKEFMSSK-KKSKIPPPPLLLSRSHCSMTFKPASFSSDVQVAWYSILGCVAGESNTKVRLNNNKLPNAGEEILADGKSLLEVQGLDPNEKYIFAVAAYSSDGKLIGDAIGETTRPILAYPPLSATTVRAYLTQVAYQTGNYTLARGAFSPMWDYFVSNSSPLPTNAAVISARSTLTISEKRLRFEAVSQTSPITLYLFLRNIFAICDINITEGALFCDSICCDEILYKEQVGRLAECERMTVAIELSNFLNDASYALQAVVQCYGLLAPIIYHKISAVPVVQILIKCLAILQEIPSATLQRRQAGCYESIQHMIACTSFYTAKVLRSWKEYELAVIIINYGKNLLDSSQ--TTATG----QPGATETEETHKIKNISAKTSHLAAMEKATENLSALESNLLRLTQPARGSKLAGQEDPLFLYPIISCWTSNTAYREVMKFRNKSRFLEFFIQVLHKILNEEKFHSVLEWAENVQTFLKRRNNHILGISETP-RQKTSSPSEPEGTKKYTVGVKEFQKSTKTSPVKKQKAPALKKKGKETPSPTRKRQTLRQYFMKHPNIMKSPEAQRKHKEELQKVAHNTLVVLLKPAVSNYLNRKKFHQICLEEMPWKSQMNIYLANAHYNLFKKKLEEQYNIGICGFHHQDSYNILDPEIFSLNNSGTVVVREAVENNRRTSNPLKSPSELTKKQTYTDRSSQHSTKLWG---------RDTPQTQMTNDMEISISLSPKECRQFPSYTILLDHFTKIFLHLRRAAVLAHRGGHWTLLQNACRELWNYTQESQSISNRSHSQKDAFPITREFLRNTVWLPFYLASDMIIDMITELQASNSLKIVEPEGDFCIPSCLGGITDENGGSNLHPQSPLDDVNVVDLKWICNLILKTLEFLYQMKKWEALVHIALQFNVFTHERYTEQVSPLLVYAQRQLLERIQQFGGPGSHESNFTKYLSDNANKLSCRDYIGQNLQLPVARSASILVFPGCFFCPEMKNDYADGSQAKPIVYVPLDVKDALQCFRESLKKSKYHSRALKHSRKLLSLFLAYTQEVVGRTISQISPDRRLEFNVGAELAFLPTPSDLSQEKFNFSSSIERKPIPQSQLSLIVSSYEQTIEILEVNNQRDLKVQALHELGNLHFYAGNKRAAFKYWCQALDETLNTDDILNTWQELG-FPKNATECFAVGRSTDICQKFLSQAGIWGCLHAAVLVAKIAQYITTSNVRLRTRYCQFSAILFKSLFRASLPHPTSDCDFAQYETQMLIPGIDLFSDRYRADISTVVASLNFLMFELHCAKQNLTILPLFTLYQYFISEICKDPAKCIEGRIFKIKVLTDIGFFTEAFHELCLLNCGERIPWKIPAGYKINEEIKTLLYFDSSKSLLSFTNLQVLEDIFNWSLSLTVVPLCNQQIMNKLILAKMHFIICLSATINNVPEKVEKCIYSVDNMPDGNTPSNVKVDAVKNFRQREQRDTVMQLIDCEAELNMAMLKGILLQEAEESLNCLVQNIQDKYDGKIYHCSAEDLEVLTEAKLQLAAISQQWHRAALSVALAFSAIRLLQDADIFRMTATNFQEE--KDKRDSLDSCVEDA--QQPHSTIAQDHLNVRLWLRCRKMLVTALATQLHSVGDKEENNVAERRSIVKEVILEAEAFGDTETQAEMMVQAAILDLQEGCPMADIKILLQNIISLLQEDKFISPPASLTLVKSMLLMTDILALQTIENMEYCSAVDPLNLLNLAHDITLKEIFSCGEYIEQQIEDSTLTCLVLPAKNIYLPYINLLAQVKMRIGNTLAERVACTPEREDPLQWLHALKHLETALKLCRASATEVLDMEAQLLFQIGKVECQIAKAGNNKPYQAVETLLEAIKLSQQHDQNFELIRRSYLEIALLYLHFATNNENLSQRDKTVPSKSEISAGELSSSPGETLKSEGYKVRAWIAVRAARQVSEAVVASQLLIGMESIKEHNVKDALQQKIPEFASMDLLASYRDYLSDEYNVVCGSHTASSTENKQTIQEDQNQNEGMECLDTSSNQKKEIITWVHLIRYHSYIEGLCHTNLFAAHKSGLGSLSG-RDGHLNSLCDSWVVLRVAEMHSFLKKHLLEYSVCCLESFPEQLRDLEVSRGCSPDSPKTSLEDSGISPKVSCVKIASQVSVVAEAGSHMESRAANASNKEISIQWYIPSLAKPANGADTKVLLLYAYNTQPVKISNVKFFSSMSVFSGQLWIPLARIISLREKLSNLKHQVEMLMQSLGNSPAAEPTSFLEQNEALKTTPSEEAEMNIARVHLDEKTEEMATRCLSEVKALLSAVPVLA----LTLTEIPFDINLQSIASLEDMFDLANGCTITEESLFSWIISLFH", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ...... . *.*:*.: **:: * * *::::: *::: :. . : . :*::** *.:***** ** **** ***:*********.*:******* ******** * : : *: . * .:**:.***:** *: * ******. :*:* **:**:** **:::**: *:::***:** **:****::***:*:***::** ***:**:****:*.**:*****:*** :****::*********:**.** :**: *****.****.* :*:**:*** :***.. . : : :****:**:******.*:***** * :***:*:**:*.*.*.****.**:** *::*.*:*:***:**** **.**:*:. * .** *::**:****:** *:* . :: * ..: **: :: .. :* *:*:* ****.****.:*:* : *** *:.*. **** :* ** ::**: :: : : :. .: : .: :.:: :.* : **: :. *... :.: ***:*:.* * :***:** *:* ::* . *:.:* .:.**:*:** *.**: :: * *:*:***:** *: ***.:... * :: : * .. : .. : ** : *.*** **: *:::* :. . ::* *.:*.*::*.* .* . :: .. *. :.**: **************** **. : :* * . . :.*: .:. ::* :* *****.**:**:**:**: :* ** :. :** ** :**:::****.*** * : *:* *:*::****:**:*:***:*:***.* *:*:.:**.**** * * *******:***:** * ***:*.:*::.*:.* :* **::***..***:*.******:*** *****: *.* :******* .** :*: .***:*****: * : :**. . :**:::*:: : :::**.* *********. .**:*.* ****.* :**: :*:.** ***.: **:********:.:*****.************:* ***:******:.:** :** .::: ..:********* ** :*:****:**:**:::*****::** : : . * .* * . *..:: ** .*:*: **::**: *: ::*:* ***:****:: *. : * :*****:::.****** *:: * :*:**** ::* * ******: ::*: . ::.. . :. *:.. * *: :*:. : ::::.*:::: *:* * . :*::: .::* * . * *:* : .*:.**:**:: ***:**::***:***.**:::. :** * : : : *:. **::*** :***:: : : .: .:* . . .: *. : . ..*: .* : . . :* : :*** **** *** ***:***:******.** :**:::* * : :: .:**:::: : *****.::::***: :** :.*:* .* .*:*.:*** *.*..:****.* : **********:** :::**:**.***::*** ** :*:*** .:********:**********: **::: ** .. ::* :: .:*::**::**:.: : : : .. : ** :* **:**.*:*:****:*:**::*.*:::*********** ** ::*:..***.****:**.**.* ::* :****** *.****: :.. *:*:.*:*:* ..... : .* .::***: ******:.*:: *****:*.: **. : * :**:**:.*:*::****.:: :**** *:***:****::****. *:*** ::: *** .: ** :***::*****:* **:* .: :*.**:**::* *: :*:***:*: : *:.:* ****** . .:* ***.* * *:*.:::: * .*. :* : :::**: :.* :*::.::**:* :*: : *: . ::: .: :: . : .: :*.:** ***: :* *:.: : : : .*. :**::.**:*:***:: * .*.* *.*: :.:: ****:.:*. : . . * . :*. :* * .::::*::****** ***:: :*::.:* :*.:::: *::.** **:: .*** **:: **.:*.*** *** *::** **: .:*:** : ***.:*::*: *: :.::: .* . * :*. ** * :::: ** ** .:: : : * ******:: ***::*:***:*:*::* . :::* :** .*: :: ***:*:::*.* ::**::*** *::* *: ::.. :*:: ***::* ::*** *:* ****:**:*::: . : : *: . . : * . : : * *. ****:*** ****:*:. :**** : .:*:: :*****: ***:** *** ::*:*: : : :*.:. : :.::. . .* :**: *:**: ::: : : . : * : ..:* * :.** :* ::** *:* ***..* *: .*:: **.:* . . * . ...:.. . . : . . ..:* ***:.:*****.* :* : ::. ******** :*: * ::: : . * **** :* :::***.* : .*: : : : .: * . :: :* . *:: .* **: :*: .::::***:.* :* .** :******* :: ***.*::*:: ", "identical_positions": 1210, "similar_positions": 998, "identity": "37.11%" }, { "cls_id": "homologset.oma.820100", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L953-1", "uniprot_id": "A0ABK0L953_RAT", "id": "A0ABK0L953-1", "name": "Cilia- and flagella-associated protein 74", "aln": "MEEPTVQFSDEELVDNFPTLDDERIQLEDLEFEVEQPPEELEDGSD---NSLAKKQSADLEKMKKTTTKDRVQALHLRKSLNLLDKMHEEKDVFIQKTKGELRICRQRMDLLDKQQESLAAEIATEKEANNMAAIGRLQAASRRLQTELENEKDLQSKITAMLKESENAMWHIEIQKGLFEDVRKHHEEEAEARQRSLKVHSAQQLQKEKEALEKSERNRLLRARKSLHTQKELGLRHQKLVEDAQRNHRIAVKFLKASLGRVREQEQKEEMESRKHMQRRMDAVLALKNNINASRETLKKFQVWSQTRAQLANQKALTEKEEILAQGGDAFKYLCHQQKHQELEAQKRAFEEEQKLRKQEIVSRILKEEAEEEQRKRRQRPPPKAIDRWTLRDRTWKYISDICEGKTVCTSTYQLD-EMLLYPKPLRVLKAISSESMQTDPGSINTEDEVLAEPDVPGLWSKESYQPHQVPKEDMERKPVGGSKMEKDILARTMERLRSGVIQKQVVSGREFKGRPFNSKPEVIHFKDFDIGKVYKKKITLINATYTINYCKLVGVEENLKDFIHIDFDPPGPMSAGMSCEVLVTFKPMINKDLEGNVSFLAQTGGFSVPLKCSTKKCSLSLDTELIDFGSYVVGETTSRMITLTNVGGLGTKFKFLLDSELYEMDDSQPIVKISSLFNCEDKTLYEKLISSYSEQQLEVNEFSSMDLLSQKESEKQLDDAEVTTAAVS---AMTMPPSEEQAEITLGEVREGEIGPFSSIKVPIIFTPIIPGEVQNKFKVVFKDPQSPTLYFRATGTAIDVPVWVPRATVDLKICMYDRLYQDSITVHTRSKAALRLKFEVCKELRGHIELLPETGYIQAQSTYSVQLKFLPRQSLPEDARKYFDPASRVLEAPMTIRVADQIKPVRFTVQAIVTTSDLEINPSEINFGYCTIYEAIRTEIRLSNLSLLPQEFGFVGLPKYIDIQPNDGFGTILPLETLRLDLIFQPIKAREYKFELICKSEINRCFKLSCQAIGVHPPLELSHYQIKFSATSLYDTSVSTLYVINSHVSMNKLIHSLPRIGSEEASPVGPTSFEFLLPPKSPITISPSVGTVLPGKRCLVQVAFQPVLPQDKIFEEAIQLLGKETETK---TKETGQKKELWKQSLSMVRVHNRERLTRTSTTQSTELQRPEVNVSSIEFQAAQATLSKAFQGKFERFVIPCVVASGDIKDRKTTEPLSFSPHNTLYLELWCPAVAPFIVVTSHNGKTVFNFGDIAVGHRSIKKITLQNICNEDLTLGYSVLNPNGPFVRLNPFSKLCSGETQTLVLSFSPRESILAQETLDIITKRGTLSLTLLGTGVASMITCSIEGNTLNMGYVLARESVSTTFKLQNESLLPIKFWVRLESLSKKKAETYQQLPKFLTSREQRTEIVGTQNYNGQSVFSISPVEGLMFPGKAQEFTVTFSPDHESLYFSDLLQVVLFEKKVSHQIFLKGAAREHMMFVEGSDPLDVPVESLAVITAFDPEHKEEAEEIKPILVTLNYVQFDTDTTTPPATRELQVGCIRTTQPSPRKPDHPLIVSSLLQLRGDIKETYKVIFVAHVVTEQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UY96-1", "uniprot_id": "CFA74_MOUSE", "id": "Q3UY96-1", "name": "Cilia- and flagella-associated protein 74", "aln": "MEEPTVQFSDEDLVDNFPPMDDERVQLEDLEFEVERPSEGLEDEGS---HSSAKKESKGAEKMRKSTTKDQVQAFHLRKSLNLLDKMHEEKDVFIQKTKGELHICRQRMDLLNKQQESLAAEIATEKEANNMAAIGRLQAASRRLQTELENEKDLQSKITAMLKDSENAMWHIEIQKGQFEDVRKHHEAEAEARQRGLEVHSARQLQREREAMEKSEKNRLLRARKSLHTQKELGLRHQKLVEDAQRNHRIAVKFLKASLGRVREREQKEEMESRTHMQRRMDAVLSLKNNITASRETLKKFQAWGQTRADLAKQKALTEKEVILSQGGDAFKYLFHQRRHQELEAQKRAFEEEQKLRKQEIVNRILKEEAEEEQRKRRQHPLSKPINRRTLRDKTWQYISDFCEGKSVLTSQQERERELLLYPKTVCVIKAISSESVQVDLGSISTEDEVLAEPDISGLWNKESYQ---VPKEDMERKPVGGSKMEKDILARTMEQLRSGVVQKQVVSGREFKGRPFNSKPEVIHFKDFDIGKVYKKKITLINATYTINYCKLVGVEENLKDFIHIDFEPPGPMSAGMSCEVLVTFKPMINKDLEGNVSFLAQTGSFSVPLKCSTKKCSLSLDKELIDFGTYVVGETTSRIITLTNVGGLGTKFKFLPDSEFYEMDESQPAMKISSLFTCEEKIIYEKIMTSLSEQQLEVNDSSLVDLQSLKESEKQLDDPEVTTAAVS---AMTMIPSEEQAEITLGEVTEGEIGPFSSVKVPITFTPVIPGEVQTKFKVMFKNPQSPPLYFRATGTAIDVPVWVPKATVDLKICMYDRLYQDSITVHTRSKAALRLKFEVCKELRGHIELLPETGYIQAQSTYSVQLKFLPRQSLPEDARKYFDPASRVLEAPMTIRVADQIKPVRFTVQAIVTTSDLEINPSEINFGYCTIYEAIRTEICLSNLSLLPQEFGFVGLPKYVDIQPNDGFGTILPLETLHLDVIFQPIKAKEYKFELVCKSEINRCFKVSCQAVGVHPPLELSHYQIKFSATSLYDTSVSTLYVINSHLSMNKMIHSLPRIGSEEAAPVGPTSFEFLLPPNSPITISPSVGTVLPGKRCLIQVAFQPVLPKEIIYKEASQILNKEIETKPVSQKEIVQRKELWKQSFSVVRVHNRDRPTRVSTPQATELQRPVINSSSTEFQIAQATLSKAFQGKFNRFVIPCVVASGDIKDRKTAEPLSFSPHNTLYLELWCPAVAPFIVVTSHKGKTDFNFGDIAVGHRSVKKITLQNICNEDLTLEYSVLNPNGPFVRLNPFNKLRSGETQTLVLSFSPHENILAQETLDIITKRGTLSLTLFGMGVASMITCSIDGNILNMGYVLARESVSTNFKLQNESSLPIKFWVRLESLSRKKAEAHQQLPKFITSHEQRAEIVGTQNYNGQSVFSIVPVEGLMFPGKAQEFTVTFSPDHESLFFSDLLKVVLFEKKVSHQILLKGAAREHMMFVEGGDPLDVPVESLAVVTAFDTEHKEEAEELKPILVTLNYVQLDTDTTTSPATRELQVGCIRTTQPSPRRPDHPLMVSTLLQLRGDVKETYKVTFVAHVVTGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0B2-1", "uniprot_id": "CFA74_HUMAN", "id": "Q9C0B2-1", "name": "Cilia- and flagella-associated protein 74", "aln": "MEDDGSLLPEDELLADALLLEDERDELEDPEFDIKCLLQEAEDDVDPGHSSSVKELDTDADKLKKKTAEDRTQAFHLRQNLSALDKMHEEQELFTEKMRGELRACRQRRDLIDKQQEAVAAEIATEEEAGNMAAVGRLQAVSRRLFAELENERDLQSRTEAVLKESENTMWHIEIQEGRLEAFRTADREEVEATGRRLQVRAAEQLCREQEALGKVERNRLLRIRKSLNTQKELGLRHQKLLEDARKNHKVAVRFLKASLGRIREQEKKEEMECHEYMRRRMDAVVALKGSISANRDTLRKFQAWDRAKAELAEQRVQAEKKAILAQGRDAFRHLVHQRRRQELEAQKRAFEEEQKLRKQEIISRILKEEAEEEKRKK-QHPPTSARHRLTLRDKTWNYISDFCKKTTVPTNTYTLDYEAAAGPGPSRLLEVVSSELIQGDPG-ASSEEETLAEPEISGLWN-EDYKPYQVPKEDVDRKPVGGTKMDKDILERTVERLRSRVVHKQVVWGREFQGRPFNSKPELLHFQDFDIGKVYKKKITLVNTTYTINYCKLVGVEEHLRDFIHVDFDPPGPLSAGMSCEVLVTFKPMINKDLEGNISFLAQTGEFSVPLKCSTKKCSLSLDKELIDFGSYVVGETTSRTITLTNVGGLGTTFKFLPASEPCEMDDSQSALKLSSLLTYEDKSLYDKAATSFSEQQLEGTESSQADMQSRKELEKLDKEQEEEQPAEPERLTTVIPPSEEQTEITLGEVTEGEIGPFSSIKVPIVFTPVVPGDVQARFKVTFKNPQCPTLHFRVVGVAIDVPVWVPKPSVDLKICMYDRLYQDSVLVHTRSKAALRLKFEVCKELRAHLELLPKTGYIQAQSSYSVQLKFLPRHSLPEDAGRYFDKETRVLEAPMTIWVADQNKPVGFTVHAIVTTSDLELSPSEVDFGYCTIYEAIRTEISLHNHSLLPQEFGFVRLPKFVDVQPNDGFGTILPLETLQFCVIFQPTKAEEHRFQLTCKSEINRCFKLSCRAVGVHPPLELSHYQIKFAATALYDTSVATVYVINSHLSMSSPTHSKPRIGSEDASPMGPTSFEFLLPPDSPITISPSVGTVWPGKRCLVQVAFRPVLPEKLIRQEALPLLNKEMETKSFRKNMAPQRKDLHGLSFSVLRAQNRDKLFKVSVPHVLEMRKRELRPSSDEYQAARATLLRAFQAKFDTFVVPCVVASGDIKDRKGSEPLSFSPHNTLYLELWCPTVAPSVVVTSHKGKTIFNFGDVAVGHRSIKKISIQNVSPEDLALDFSLLNPNGPFVLLNHSSLLRAGGTQVLVLSFSPHESILAQETLDIITKRGTLTLTLMGTGVASMITCSIEGSVLNMGYVIAGESVSSGFKLQNNSLLPIKFSMHLDSLSSTRGRGQQQLPQFLSSPSQRTEVVGTQNLNGQSVFSVAPVKGVMDPGKTQDFTVTFSPDHESLYFSDKLQVVLFEKKISHQILLKGAACQHMMFVEGGDPLDVPVESLTAIPVFDPRHREEAEELRPILVTLDYIQFDTDTPAPPATRELQVGCIRTTQPSPKKPDHPLMVSALLQLRGDVKETYKVIFVAQVLTGP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: :.:::*: : ::*** :*** **::: : ** . * .*: . . :*::*.*::*:.**:***:.*. *******:::* :* :***: **** **::****::*******:**.****:*****.**** :*****:****: *:**:***:*******:* :* .*. .. *.** * *:*::*.** :*:**: * *:***** ****:************:***::**::**:********:**:*:*****.: :*:******::**..*.*.*:**:***.*.:::*:**:*:. :**: **:** ***::* **:::*********************:.**********:**: *:* ... .* ****:**:****:*: .:* *. : * * . :::.:*** :* * * .:*:*.****::.***. *.*: *****::******:**:**** **:*:*** *::**** ****:*********::**:**************:*:**************:*:****:**:****:***********************:******* *****************.******:********* ***********.**** ** ***:**. :*:***:. *:* :*:* :* ****** .: * *: * ** ** .: * .* . : .: *****:******* *********:**** ***::**:** :*** **:**.*.*:**..*.*********:.:***************: ********************.*:****:********:**********:****** :*** :********* **** *** ***:*********:.***::************** * * ********** ***::*:***************:: :**** **.*::*:* **********:**:*:***************:**:******:*:******:**.. ** ******:*:*:***********.************ ******:****:****:. * :** :*.** *** : *:*:* *:*::*.:**:: :.*..: *::: :. ** *:* *:*** :***.**: **:************* :******************:*** :*****:*** *****:******:***::**:. ***:* :*:******** ** . * :* **.*******:*.****************:***:* **********:*. ******:* ****: *****:* ***** ::*:*** .:.. ****:*::* .**:*:***** *******: **:*:* ***:*:************:*** *:*******:****:***** :*******.**********:.:..**..*:*****::******:*:*:****.:.******************::*****:**:*******:****** ***:*:* ", "identical_positions": 1059, "similar_positions": 341, "identity": "66.73%" }, { "cls_id": "homologset.oma.820170", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1LWD2-1", "uniprot_id": "F1LWD2_RAT", "id": "F1LWD2-1", "name": "", "aln": "MALQAWDWEEEERASTRPLSTASDYHSASECETEEYPKSRTPGNEWDSEDQFSS-LHSSEGPACISNSDVPQVVPCKFVISLAFPSLLGNKGKPTNVPDK-KKAAKSENRAGKARQFYHIEYFFLPDDIEPKIVDIVVFPNVAKVFLDSGIKTVKPWKDDDKFWVSWSQTFHVNMTKELLKKMNFHKITLKLWDTKDKVSKKVRYHRVKTSAYSEDSDSF--EEVKNLVLSQKRLSVIVDGKVNIVPEELKEENVPGDQEKAEKHSKSPQ-----EPETPSKN-EECEKLLKMEES-SSRRTTMKTP-ISLSGATMMEIKELIEKPSLSSLTNMVEKQKSQLKGKEIEVKKKNPKKVKKYQTEEERDQRQEG-APWKQSTFSIQLPVMPLLAGWQTVICRGSEKSANILDCFLTLKTEVPIMTEEQKQELNPLTIKIRCASCLPVQPVSIHDLERLCSPVYCRYQFHKTPVHETKGEPHGTHVFFHDLNVIFLGAMHPSDLREYLEGPPMVVEVHDRDRKSEEYSRKPTLFGEDLIDSYYNLQAFISSKDTENNPFESQNKIWDPYGVAKVSFADLLLGYKYLNLIVPIHNCEPKSPNWSQDSRSRRTIGLQAPTDV-QHSSVPIGNYLEANSLLKLRVDVAVPLSSSWSRVPEFNLMGTHFGRIIFVFSAKKLSLLQNLLHDITVINAKALELDSYPLQKIQQILSAFKVRVKIQEQQSLDVLTGFHLLDGKIHLFILEGLADHGLRRLWESYQSSVTTSNRAACKVLYDSRLLFRHRLYADLETVLFHVHLFRPVSVLLRYPALYVRGAVSRMTFQALSRIHDICHSSTKLKDVISRDLLPSSCMIKDLSQEFGVPISQEELIDGQVLPVSPQLDDNEEDVQHQTSNLPLEIQVHQDKYLQWRNNMLLKNQVHRDSVVQKNITEAYQFTKQSQKSMKRIIRIAIPENKTVHNYSTQTMNSTELAKKQMLQEMAKEPRKRFTYSQNYLSAMVDLQDPKEEEKKAQKKSRQAWLTAGGFQVWGLQSAIGSHQQDLRLPPIRELNEEWQESALFANVLKPVLDRERWGWSQRHKDFDLYKKPPLDFQLPSLLAPKRASGGRRKADIRSSEQRWRSQVTPRPPSLHGSISMQPHDLFSLSDP----------------SSCTKHSVSPNLHVS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A571BDQ7-1", "uniprot_id": "A0A571BDQ7_MOUSE", "id": "A0A571BDQ7-1", "name": "", "aln": "MSLQAWDWEGEEGSSMGPHSVAS------ESEMEENLKSRIPAHDWDSEDQFSSSLHSSEGPACISNSDVPQIVPCRFEISLAFPVLIGNKGKPPNVPDK-KKSAKTETRTGKARQFYHIEYFFLPDDIEPKIVDIVVFPNVAKVFLESGTKTVKPWRDDDKVWVSWSQTFHVNVTKELLKKLNFHKITLRLWDTKDRVSKRARYQRVKASAYSEDLESL--EEVKHLVLSHKKLSLISIGKTNPISEELKEENLPGDQEKSEKHLKSPQ-----EPEAPSKNDEECEKLLKMEESPLSRRTISKTP-ISLSGATMMEIKELIEKPSLSSLTNMLEKQKSQLKGKDTEVKKKNPKKVKRYQAEEEGDQKPETPAAWKQSIFSIQLPIMPLLAGWRTVICRGSEKSANILDCFLTLKTEVPIMTEQQKQDLNPLTIKIRCVSCLPIQPVSIHDLERLCSPVYCRYQFHKTPVHETKREPHGTHVFFRDINVVFLGAMNPSDVREYLEGPPMVVEVHDRDRKLEEYSRKPALFGEDLMDSYFNLQAFVSHRDTETNPYESQNKIWDPYGIARVSFADLLLGYKYLNLIVPIHNCEPKSPNWSQDSRNRRTMGVQVPTDVLQHSSIPKGNYLEANSLLKLRVDIAVPLSG-WSRAPQLDLMGTHFGRIIFVFHAKKLSLLQSLLQDITMINAKALELDCYPLQNIQQILSAFKVRVKIQEQQDLDVLTGFHLLDGKIHLFILEGLADRGLRQLWESYQSSVTASNRAACKVLYDSRLLFCHRLYADLETILYHVHLFRPVSVLLRYPALYVRGAVSRMAFKALSRIHDICQSSTRLKEVVMRDLLPSSSMIKELSQEFGIPISQEDLTDGKLLTALPQPDTSNEDIQRRTSTLPLEIQVHQEKYLQWRNDMLLKNQVHRDSIVQKNITEAYQFTKKSQKPIRKVIRIAIPENKTVHNYSAQTMNSTELAKKQMLKEMAKEPRKRFTYSQNYLSAMVDFQDPKEEEKKAQKKSRQAWLTAGGFQVWGLQSSTGSSQQDLKLPPIRELNEEWQENALFTNVLKPVLDRDRWSWSQRHLDFDLYKKPPLYFKLPRLPSPKRASGRRRKANIGSSGRRWRSRVASKPLSSPESSSTHPQDLFSLSDHHLVLKTLSRLTSASRGSSLGLYHPNPTFHSRWFH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULG3-1", "uniprot_id": "CFA92_HUMAN", "id": "Q9ULG3-1", "name": "Uncharacterized protein CFAP92", "aln": "MSLHAWEWEEDPASIEPISSITSFYQSTSECDVEEHLKAKARAQESDSDRPCSS-IESSSEPASTFSSDVPHVVPCKFTISLAFPVNMGQKGKYASLIEKYKKHPKTDSSVTKMRRFYHIEYFLLPDDEEPKKVDILLFPMVAKVFLESGVKTVKPWHEGDKAWVSWEQTFNITVTKELLKKINFHKITLRLWNTKDKMSRKVRYYRLKTAGFTDDVGAFHKSEVRHLVLNQRKLSEQGIENTNIVREESNQEHPPGKQEKTEKHPKSLQGSHQAEPETSSKNSEEYEKSLKMDDSSTIQWSVSRTPTISLAGASMMEIKELIESESLSSLTNILDRQRSQIKGKDSEGRRKIQRRHKKPLAEEEADPTLTG--PRKQSAFSIQLAVMPLLAGTHCLPCS--------QQLLLVLWPERP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*:**:** : : * :* *.: ** *:: .:: **: ** :.**. **. .****::***:* ****** :*:*** ..: :* ** .*::. . * *:*******:**** *** ***::** ******:** ******::.** ****.***::.:*******:*******:**:***::*::.** *:*::.:::* :: .**::***.:::** :.* : ** ::*: **.***:*** ** * ***:.*** ** ** ***::* : : :** ***:**:*********. *******::::*:**:***: * ::* :: *: :*** * . *** *****.:****** : : * : :*.* .* * ", "identical_positions": 202, "similar_positions": 110, "identity": "17.21%" }, { "cls_id": "homologset.oma.820190", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8V0Z465-1", "uniprot_id": "A0A8V0Z465_CHICK", "id": "A0A8V0Z465-1", "name": "", "aln": "MSYRDVRNLTEMLRALGYPRLVSMENFHAPNFALVAELLLWLVRRYEPQSDIPPDVETEQDRVFFIKAVAQFMATKAHIKLNTKKLYQADGYAVRELLKVTSVLYSAMNTEGMERTDITEEDSSKFKFDLGSKIADLKAARQLASEITSKGANLYDLLGKEVELREARTESIARPLEINEAEKMMKVAIDCVLEEVQKTKDMLSNVALDEANLEAKIEKRKSELERSQKRLQTLQSVRPAFMDEYEKIEEQLQKQYTSYLEKFHNLTYLEQLLDDQHRTEQEMFEEAANMLRLMQNRLKEEEQRLLKSGSNDDSDMEIQEDEGSDSEVEDRQFRKQRTALDTLVPGRAGARIVGAMQGGDTEEDEESGDSEIDLDDDEDEEEDVEDDSMEISPSKSSHRAKKPEPLEESDNDF", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "F6PWT1-1", "uniprot_id": "F6PWT1_BOVIN", "id": "F6PWT1-1", "name": "", "aln": "MSFRDLRNFTEMMRALGYPRHISMENFRTPNFGLVSEVLLWLVKRYEPQNDIPSDVETEQDRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSKRAEEDVSKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGKEVELRELRTEAVARPLEINETEKVMRIAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQSVRPAFMDEYEKIEEELQKQYEIYLEKFRNLAYLEQQLEDHHRMEQERFEETENTLRLMQNKLKEEGKRLLKSGSNGDSDVDIQEDDESDSELEERRLSQLRTAMEVLTQGQPSKHVVGTMQGGDTDDDEDLEDSEIDMEDDEDDD-DLEDESVALSAAKPSRRGRKPEPLEESDSDF", "tax_id": 9913, "tax_name": "Bovine" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:**:**:***:******* :*****::***.**:*:*****:*****.***.**************:*************************:****:*****.**:*:*** :. :*** *****************************.************* ***::********:**:*::**. :* :******:*.*** ************* ****.:**********************:***** *****:**:**** *:*:** *** ***: * ******:**** :********.***::****: ****:*:*:: : ***::.*. *:.. ::**:******::**: *****::****:: *:**:*: :*.:*.*:*.:*********.**", "identical_positions": 306, "similar_positions": 81, "identity": "74.09%" }, { "cls_id": "homologset.oma.820191", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYJ5-1", "uniprot_id": "CLUA1_RAT", "id": "Q6AYJ5-1", "name": "Clusterin-associated protein 1", "aln": "-----------MMRALGYPRHISMENFRTPN-----FGLVSEVLLWLVKRYEPQTDIPSDTETEQDRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSNVGEEDISKFK-FDLGSKIADLKAARQLASEITAKGASLYDLLGKEVELRELRTEAIARPLEINETEKVMRIAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQSVRPAFMDEYEKVEEELQKQYDVYLEKFRNLAYLEQQLEDHHRMEQER-----FEEAENTLRLMQNKLKEEEKRLLKSGSNDDSD----------------------------IDIQEDD--ESDSELEDRRLSKPRTAMEVLMQ--GRPSKRIVG---------------------TMQGGDSD-----------------EDEDS----EDSEMNME-------------------------------DDEEDDDDLEDESIA-LSPAKPSRRVRKPEPLDESDNDF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R3P7-1", "uniprot_id": "CLUA1_MOUSE", "id": "Q8R3P7-1", "name": "Clusterin-associated protein 1", "aln": "MSFRDLRNFTEMMRALGYPRHISMENFRTPN-----FGLVSEVLLWLVKRYEPQTDIPSDIETEQDRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSNVGEEDISKFK-FDLGSKIADLKAARQLASEITAKGASLYDLLGKEVELRELRTEAIARPLEINETEKVMRIAIKDLLAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQSVRPAFMDEYEKVEEDLQKQYDVYLEKFRNLAYLEQQLEDHHRMEQER-----FEEAENTLRLMQNKLKEEEKRLLKSGSNDDSD----------------------------IDIQEDD--ESDSELEDRRMSKPRTAMEVLMQ--GRPSKRIVG---------------------AMQGGDSD-----------------EDEDS----EDSEIDME-------------------------------DDEEDDDDLEDESIA-LSPAKPSRRIRKPEPLDESDNDF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A061I302-1", "uniprot_id": "A0A061I302_CRIGR", "id": "A0A061I302-1", "name": "", "aln": "MSFRDLRNFTEMMRALGYPRHISMENFRSPN-----FGLVSEVLLWLVKRYEPQTDIPSDIETEQDRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSKVGEEDISKFK-FDLGSKIADLKAARQLASEITAKGASLYDLLGKEVELREMRTEAIARPLEINETEKVMRIAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQSVRPAFMDEYEKIEEELQKQYDIYLEKFRNLAYLEQQLEDHHRMEQER-----FEEAENTLRLMQNKLKEEEKRLLKSGSNDDSD----------------------------IDIQEDD--ESDSELEERRLSKPRTAMEVLMQ--GRPSKRIVG---------------------TMQGGDSD-----------------EDEDS----EDSEIDME-------------------------------DDEEDDDDLEDESIA-LSPAKPSRRVRKPEPLDESDNDF", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q96AJ1-1", "uniprot_id": "CLUA1_HUMAN", "id": "Q96AJ1-1", "name": "Clusterin-associated protein 1", "aln": "MSFRDLRNFTEMMRALGYPRHISMENFRTPN-----FGLVSEVLLWLVKRYEPQTDIPPDVDTEQDRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEIVEEDVNKFK-FDLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQER-----FEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSD----------------------------IDIQEDD--ESDSELEERRLPKPQTAMEMLMQ--GRPGKRIVG---------------------TMQGGDSD-----------------DNEDS----EESEIDME-------------------------------DDDDEDDDLEDESIS-LSPTKPNRRVRKSEPLDESDNDF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VR64-1", "uniprot_id": "Q9VR64_DROME", "id": "Q9VR64-1", "name": "", "aln": "MSFKDVRDLGEHLKLLGFPRVFPLQSLANQHGSLASFHIVAELLQWLAGLIEPGATLPGGVESEEQRVLLVRSATEFFVTKAAIRINPRKLYAAAAVTAAELQKVTRLLTSPGQNEADNDEEDQRDQYRSLNPVDIGDKIEELRKARELATDLTQRGTTICEMLSKELLHKESLMSQAQRPLELLSVERTLKSAIQANQVRLQSSRAQLEAAKVELNALGSKLQRRRAELERTRQRLEALHRIRPAHMAEFEDCEKELQELFQRYFLRLHVRDALKSQLDLRTKRATPISSPILQKPAENSMPFIPEGLIEDDDDDDDEDDLDDEDEGDDGGKALSRLEMVVNGRSVFGLDSEIPDIRDEDKLMQQNNMVSAQGKRPGTATSRIRPTTGRSRKAVGGRGTAGPDGGNDARAARGTRRGVATGGDADGTQLNGRNGPGSSMLNSRDEDSSFGSSESELDVGKIMGMSGMSGMSGMSAISGISGMSNIALGAGDDDFDLNSIDDISISKLTGELPLRPKTANKAEHHSDEDF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3MHC1-1", "uniprot_id": "NAA60_RAT", "id": "Q3MHC1-1", "name": "N-alpha-acetyltransferase 60", "aln": "-------------------------------------------------------------------------MTEVVPSSALSEVSLRLLCHDDIDTVKHLCGDWFPIEYP--------DSWYRDITSNKKFFSLAATYRGAIVG-MIVAEIKNR-TKIHKEDGDILASSFSVDTQVAYILSLGVVKEFRKHGIGSLLLES-----LKDHISTTAQDHCKAIYLHVLTTNNTAINFYENRDFRQHHYLPYYYSIRGVLKDGFTYVLYINGGHPPWTILDYIQHLGSAL--------ANLSPCSIPHRIYRQAHSLLCS-------------------------------------------FLPWSSISSKGGIEYSRTM-----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.. :.* .:. : * :. .* : . .. .: . : ..:. . . :.:::. : :.: . . : *.: .:. : .* . : : : :.. .: : .* . : . : : *. :. *: : *: : : . : .: . . ..: . . : ", "identical_positions": 9, "similar_positions": 83, "identity": "1.7%" }, { "cls_id": "homologset.oma.820200", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NZN9-1", "uniprot_id": "AIPL1_HUMAN", "id": "Q9NZN9-1", "name": "Aryl-hydrocarbon-interacting protein-like 1", "aln": "MDAALLLNVEGVKKTILHGGTGELPNFITGSRVIFHFRTMKCDEERTVIDDSRQVGQPMHIIIGNMFKLEVWEILLTSMRVHEVAEFWCDTIHTGVYPILSRSLRQMAQGKDPTEWHVHTCGLANMFAYHTLGYEDLDELQKEPQPLVFVIELLQVDAPSDYQRETWNLSNHEKMKAVPVLHGEGNRLFKLGRYEEASSKYQEAIICLRNLQTKEKPWEVQWLKLEKMINTLILNYCQCLLKKEEYYEVLEHTSDILRHHPGIVKAYYVRARAHAEVWNEAEAKADLQKVLELEPSMQKAVRRELRLLENRMAEKQEEERLRCRNMLSQGATQPPAEPPTEPPAQSSTEPPAEPPTAPSAELSAGPPAEPATEPPPSPGHSLQH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q95MP1-1", "uniprot_id": "AIPL1_BOVIN", "id": "Q95MP1-1", "name": "Aryl-hydrocarbon-interacting protein-like 1", "aln": "MDATLLLNVEGIKKTILHGGTGDLPNFITGARVTFHFRTMKCDEERTVIDDSKQVGHPMHIIIGNMFKLEVWEILLTSMRVSEVAEFWCDTIHTGVYPILSRSLRQMAEGKDPTEWHVHTCGLANMFAYHTLGYEDLDELQKEPQPLIFIIELLQVEAPSQYQRETWNLNNQEKMQAVPILHGEGNRLFKLGRYEEASNKYQEAIVCLRNLQTKEKPWEVQWLKLEKMINTLILNYCQCLLKKEEYYEVLEHTSDILRHHPGIVKAYYVRARAHAEVWNEAEAKADLEKVLELEPSMRKAVQRELRLLENRLEEKREEERLRCRNMLG--------------------------------------------------------", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q9JLG9-1", "uniprot_id": "AIPL1_RAT", "id": "Q9JLG9-1", "name": "Aryl-hydrocarbon-interacting protein-like 1", "aln": "MDVSLLLNVEGVKKTILHGGTGELPNFITGSRVTFHFRTMKCDEERTVIDDSKQVGQPMNIIIGNMFKLEVWETLLTSMRLGEVAEFWCDTIHTGVYPMLSRSLRQVAEGKDPTSWHVHTCGLANMFAYHTLGYEDLDELQKEPQPLIFLIELLQVEAPNEYQRETWNLNNEERMQAVPLLHGEGNRLYKLGRYDQAATKYQEAIVCLRNLQTKEKPWEVEWLKLEKMINTLILNYCQCLLKKEEYYEVLEHTSDILRHHPGIVKAYYMRARAHAEVWNAEEAKADLEKVLELEPSMRKAVLRELRLLESRLADKQEEERQRCRSMLG--------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q924K1-1", "uniprot_id": "AIPL1_MOUSE", "id": "Q924K1-1", "name": "Aryl-hydrocarbon-interacting protein-like 1", "aln": "MDVSLLLNVEGVKKTILHGGTGELPSFITGSRVTFHFRTMKCDDERTVIDDSKQVGQPMSIIIGNMFKLEVWETLLTSMRLGEVAEFWCDTIHTGVYPMLSRSLRQVAEGKDPTSWHVHTCGLANMFAYHTLGYEDLDELQKEPQPLVFLIELLQVEAPNEYQRETWNLNNEERMQAVPLLHGEGNRLYKLGRYDQAATKYQEAIVCLRNLQTKEKPWEVEWLKLEKMINTLILNYCQCLLKKEEYYEVLEHTSDILRHHPGIVKAYYMRARAHAEVWNAEEAKADLEKVLELEPSMRKAVLRELRLLESRLADKQEEERQRCRSMLG--------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.:*******:**********:**.****:** *********:********:***:** ************* ******: ****************:*******:*:*****.********************************:*:******:**.:********.*.*:*:***:********:*****::*:.******:**************:***********************************************:********** ******:*********:*** *******.*: :*:**** ***.**. ", "identical_positions": 279, "similar_positions": 40, "identity": "72.66%" }, { "cls_id": "homologset.oma.820201", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O08915-1", "uniprot_id": "AIP_MOUSE", "id": "O08915-1", "name": "AH receptor-interacting protein", "aln": "MADLIARLREDGIQKRVIQEGRGELPDFQDGTKATFHFRTLHSDNEGSVIDDSRTRGKPMELIVGKKFKLPVWETIVCTMREGEIAQFLCDIKHVVLYPLVAKSLRNIAEGKDPLEGQRHCCGIAQMHEHSSLGHADLDALQQNPQPLIFHIEMLKVESPGTYQQDPWAMTDEEKAKAVPVIHQEGNRLYREGQVKEAAAKYYDAIACLKNLQMKEQPGSPDWIQLDLQITPLLLNYCQCKLVAQEYYEVLDHCSSILNKYDDNVKAYFKRGKAHAAVWNAQEAQADFAKVLELDPALAPVVSRELRALETRIRQKDEEDKARFRGIFSH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3I3Z1-1", "uniprot_id": "G3I3Z1_CRIGR", "id": "G3I3Z1-1", "name": "AH receptor-interacting protein", "aln": "MADLIARLREDGIQKRVIQEGRGELPDFQDGTKATFHFRTLHSDDEGSILDDSRTRGKPMELIIGKKFKLPVWETIVCTMREGEIAQFLCDVKHVVLYPLVAKSLRNIAEGKDPLEGQRHCCGIAQMHEHNSLGHADLDALQQNPQPLIFHIEMLKVESPGTYQQDPWAMTDEEKAKAVPLIHQEGNRLYREGQVKEAAAKYYDAIACLKNLQMKEQPGSPDWIQLDLQITPLLLNYCQCKLVAQEYYEVLDHCSSILNKYDDNVKAYFKRGKAHAAVWNAQEAQADFAKVLELDPALAPVVSRELRALETRIRQKDEEDKARFRGIFSH", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q5FWY5-1", "uniprot_id": "AIP_RAT", "id": "Q5FWY5-1", "name": "AH receptor-interacting protein", "aln": "MADLIARLREDGIQKRVIQEGRGELPEFQDGTKATFHFRTLHSDPEGSVIDDSRARGKPMELIIGKKFKLPVWETIVRTMREGETAQFLCDVKHTVLYPLVAKSLRNIAEGKDPLEGQRHCCGIAQMHEHSSLGHADLDALQQNPQPLIFHIEMLKVESPGTYQQDPWAMTDEEKAKAVPLIHQEGNRLYREGQVKEAAAKYYDAIACLKNLQMKEQPGSPDWIQLDLQITPLLLNYCQCKLVAQEYYEVLDHCSSILNKYDDNVKAYFKRGKAHAAVWNAQEAQADFAKVLELDPALAPVVSRELRALEARIRQKDEEDKARFRGIFSH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00170-1", "uniprot_id": "AIP_HUMAN", "id": "O00170-1", "name": "AH receptor-interacting protein", "aln": "MADIIARLREDGIQKRVIQEGRGELPDFQDGTKATFHYRTLHSDDEGTVLDDSRARGKPMELIIGKKFKLPVWETIVCTMREGEIAQFLCDIKHVVLYPLVAKSLRNIAVGKDPLEGQRHCCGVAQMREHSSLGHADLDALQQNPQPLIFHMEMLKVESPGTYQQDPWAMTDEEKAKAVPLIHQEGNRLYREGHVKEAAAKYYDAIACLKNLQMKEQPGSPEWIQLDQQITPLLLNYCQCKLVVEEYYEVLDHCSSILNKYDDNVKAYFKRGKAHAAVWNAQEAQADFAKVLELDPALAPVVSRELRALEARIRQKDEEDKARFRGIFSH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A4X1T3G1-1", "uniprot_id": "A0A4X1T3G1_PIG", "id": "A0A4X1T3G1-1", "name": "AH receptor-interacting protein", "aln": "MADIIARLREDGIQKRVIQEGRGELPDFKDGTKATFHYRTLRSDEEGAVLDDSRLRGKPMELIMGKKFKLPVWETIVCTMREGEIAQFRCDVKHVVLYPLVAKSLRNIAAGKDPLEGQRHCCGIAQMHEHSSLGHADLDALQQKPQPLIFDIEMLKVENPGTYQQDPWAMTDEEKVKAVPVIHQEGNRLYREGHVKEAAAKYYDAIACLKNLQMKEQPGSPDWIQLDQQITPLLLNYCQCKLVAEEYYEVLDHCSSILNKYDDNVKAYFKRGKAHAAVWNAQEAQADFAKVLELDPALAPIVSRELRALEARIRQKDEEDKARFRGIFSH", "tax_id": 9823, "tax_name": "Pig" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:**********************:*:********:***:** **:::**** ********:************* ****** *** **:**.************** *************:***:**.************:******.:******.****************.****:************:***************************:***** ***************.:*******************************************************:*********:*******************", "identical_positions": 297, "similar_positions": 26, "identity": "90.0%" }, { "cls_id": "homologset.oma.820216", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O94763-1", "uniprot_id": "RMP_HUMAN", "id": "O94763-1", "name": "Unconventional prefoldin RPB5 interactor 1", "aln": "-------------------MEAPT-------------------VETPPDPSPPSAPAPALVPLRAPD----------------VARLREEQEKVVTNCQERIQHWKKVDNDYNALRERLSTLPDKLSYNIMVPFGPFAFMPGKLVHTNEVTVLLGDNWFAKCSAKQAVGLVEHRKEHVRKTIDDLKKVMKNFESRVEFTEDLQKMSDAAGDIVDIREEIKCD-FEFKAKHRIAHKPHSKPKTSDIFEADIAN---DVKSK-DLLADKELWARLEELERQEELLGELDSKPDTVIANGEDTTSSEEEKEDRNTNVNAMHQVTDSHTP--CHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKRKNSTGS--GHSAQELPTIRTPADIYRAFVDVVNGEYVPRKSILKSRSRENSVCSDTSESSAAEFD-DRRGVLRSISCEEATCSDTSESILEEEPQENQ----KKLLPLSVTPEAFSGTVIEKEFVSPSLTPPPAIAHPALPTIPERK--EVLLEASEETGKRVSKFKAARLQQKD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0ZSX9-1", "uniprot_id": "A0A8V0ZSX9_CHICK", "id": "A0A8V0ZSX9-1", "name": "Protein phosphatase 1 regulatory subunit 19", "aln": "-------------------MEAPG-------------------GASP--------LSPALV-----------------------GRLRQEHEKVVTTCQEKIQHWKKVESDYEVLQERLRTLPDKLSYDIMVPFGPLAFMPGKLVNTNEVTVLLGDNWFSKCSAKQAVELVEHRKKYVRKAVDDLQKVMKNFESRVEFTEDLQKMSDAAGDFVDIREEIKDDSIETKGKYRTAHKPHSKPKVSDAFEVDFLANGRDTKSVGRFQSEEELWARLEELERQEEILGELDRMPDTVETNGEDTTSSEEEKEDKRMDLNGTYRVEDCITQGNFQKEVTNSDLFVRHVN--------GSTYYHSDDEDDTD---------------------VGDSSVPTIFFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKRKNSNGNGHGHATPELPNIKTPADIYRVFVDVVNGEYVPRKSILKSRSRENSVCSDTSENSAAEFD-DRRGVQRSISCDEATQSDNSEGILEEEEEVGQQQLPKKLPASSGTTEAFSGTVIEKEPLSPSLIPHPVIAHPVLPTILEQKSEEVLSKASEETTKRISKFKAARMQQTN", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "A0ABK0M3M5-1", "uniprot_id": "A0ABK0M3M5_RAT", "id": "A0ABK0M3M5-1", "name": "Protein NNX3", "aln": "MEDFLCQLGFSFSDLAWGILETPIPSTYRKSHILDMTRLRDEADPRISSLVSLSLCSPSTMKERSRSPLTPITMMFILSRAKHTWVEPSETESVVTNCQEKIQHWEKVDNDYSALQERLRTLPDKLSYDIMVPFGPLAFMPGKLVHTNEVTVLLGDNWFAKCSAKQAVGLVEHRKEHVRKTIDDFKKVLKNFESRVEFTEDLQKMSDAAGDFVDIREEIKSD-FEFKGKQRIAHKPHSKPKTSDIFEAEFEN---GIKPQGTFDDD-ELWARLEELERQEELLGELKSKPDTVIANGEDTVSSEEEKEDEDTGVNVVSPVTDSSAPSSCKRHGGNAGLPNGQTSS-LNYSVNGSNSYHSNKEDEEEEEEEDEDDDEEDDDDESDHAVSADNSIPTIYFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKRKSGAAS---HSAHELPAIRSPADIYRVFVDVVNGEYIPRKSILKSRSRENSVCSDTSESSAADVDIDRRAPLRSPSSEE---TEAGSSTLEELQENHP-----KKPLPSGVSEAFSGTVIEKEFLSPSLAPHSAIAHHALPTIPERK--EVLSEASEEPAKRVSKFRAARLQQRN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TLD5-1", "uniprot_id": "RMP_MOUSE", "id": "Q3TLD5-1", "name": "Unconventional prefoldin RPB5 interactor", "aln": "-------------------MEPPS-----------------EPEPEPQPLAEASAAAPLRAPEVAR--------------------LREEQEKVVTNCQEKIQHWEKVDNDYSALQERLRTLPDKLSYDVMVPFGPLAFMPGKLVHTNEVTVLLGDNWFAKCSAKQAVGLVEHRKEHVRKTIDDFKKVLKNFESRVEFTEDLQKMSDAAGDFVDIREEIKSD-FEFKGKQRIAHKPHSKPKTSDIFEADFEN---GVKPKNTFDAD-ELWARLEELERQEELLGELESKPDTVIANGEDRVSSEEEKEGADTGVNVVSPVTDSSAASSCKRRAGNAGLPNGQVNS-LNYSVNGSNSYHSNK-DDDEEEEDDDDDDDEDDDNESDHAISADNSIPTIYFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKRKSGAGS---HATHELPAIKSPADIYRVFVDVVNGEYVPRKSILKSRSRENSVCSDTSESSAADVE-DRRGLLRSTSSEEAVATEAGGSSLDELQENHP-----KKPLPSGVSEAFSGTVIEKEFLSPSLAPYSAIAHHALPTIPERK--EVPSEVSEEPTKRVSKFRAARLQQRS", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.* :* .* *.***.***:****:**:.**..*:*** ********::******:********:*************:******** ******::***::**::**:**********************:******** * :* *.* * *********.** **.:: . *. : : **************:****. **** :**** .*******. .:* * *. : :: .: :.. **. ***:. *: : .*.*:***:**********************************.. .. *:: *** *::******.*********:*********************.***:.: ***. ** *.:* :: . . *:* : * * ..*********** :**** * ..*** .**** *:* ** :.***. **:***:***:** .", "identical_positions": 304, "similar_positions": 98, "identity": "50.25%" }, { "cls_id": "homologset.oma.820515", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F7FAH8-1", "uniprot_id": "F7FAH8_RAT", "id": "F7FAH8-1", "name": "Origin recognition complex subunit 6", "aln": "MESDLVRHLARRLGLGE-PSVLR---------------------------------------------KAEEYLRLSKVKCVSLSAHTSETSNAVICLDLAASCRKCPLDRAYLIKLSGLNKKMYQSCLKSFECLLGLNSNIGLRDLAVQFSCTEAVNLAAGILQS----YESSLPEAQRADLDLSRPLFTTAALLSACKILKIKVDKTKMITTSGVKKTIFDRLCTQLEKIGQQIN---RDSADLASPALKKKKPAFSPALKKKKSGLEQPAKDIEVIETSDKLPKDAGLTQDYEEWKRKILENAAKAQTAAVE----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3I8H4-1", "uniprot_id": "G3I8H4_CRIGR", "id": "G3I8H4-1", "name": "Origin recognition complex subunit 6", "aln": "MASELVRRLAPRLGLAE-PGVLR---------------------------------------------KAEEYLRLSKVRCSSLSAHSSETSSAVICLDLAASCMKCPLDRAYLIKLSGLNRKMYQSCLKSFECLLGLNSNIGIRDLAVQFDCTEAVDMASNILQS----YESSLTEAQQADLDLSRPLFTTAALLSACRILKLKVDKTKMITTSGVKKAIFDRLCKQLEKIGQQVN---RDSGDLASPALKKKKPLVELPAKELK----------EVIETPHKPRKDEGLTQDYEEWKRKILENAAKAQTAIAE----------------------", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q2HJF3-1", "uniprot_id": "ORC6_BOVIN", "id": "Q2HJF3-1", "name": "Origin recognition complex subunit 6", "aln": "MESGLIRRLAPRLGIAE-QEVLR---------------------------------------------KAEEYLRLSRVKCVGLSARTTETSNAVMCLDLAASCMKCPLDRAYLIKLSGLNKKMYQSCLKSFECLLGLNSNIGIRDLAVQFSCTEAVNLASKILQS----YESSLPQTQQVDLDLSRPLFTTAALLSACKILKLKVDRNKMAATSGVKKAIFDRLCKQLEKIGQQID---REAGDSVTPPQKKKKTVIEPSAKEIEN----------VVETLPKPQKDEDLTQDYEEWKRNILENAARAQKAATQ----------------------", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A8D1UKC8-1", "uniprot_id": "A0A8D1UKC8_PIG", "id": "A0A8D1UKC8-1", "name": "Origin recognition complex subunit 6", "aln": "MDSGLIRRLAPRLGIAE-PEVLR---------------------------------------------KAEEYLRLSHVKCIGLSAHTTETSNAVMCLDLAASCMKCPLDRAYLIKLSGLNKKMYQNCLKSFEYLLGLNSNIGIRDLAVQFSCTEAVNMASKILQS----YESSLPQTQHVDLDLSRPLFTTAALLSACKILKLKVDKNKMTATSGVKKAIFDRLCKQLEKIGQQID---REPEDSATPPRKKKKTVVEPPAKETEN----------IVEIPHKSQKDEDVTQDYEEWKRKILENAAKAQKATTE----------------------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q9Y5N6-1", "uniprot_id": "ORC6_HUMAN", "id": "Q9Y5N6-1", "name": "Origin recognition complex subunit 6", "aln": "MGSELIGRLAPRLGLAE-PDMLR---------------------------------------------KAEEYLRLSRVKCVGLSARTTETSSAVMCLDLAASWMKCPLDRAYLIKLSGLNKETYQSCLKSFECLLGLNSNIGIRDLAVQFSCIEAVNMASKILKS----YESSLPQTQQVDLDLSRPLFTSAALLSACKILKLKVDKNKMVATSGVKKAIFDRLCKQLEKIGQQVD---REPGDVATPPRKRKKIVVEAPAKEMEK----------VEEMPHKPQKDEDLTQDYEEWKRKILENAASAQKATAE----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V1A1P6-1", "uniprot_id": "A0A8V1A1P6_CHICK", "id": "A0A8V1A1P6-1", "name": "Origin recognition complex subunit 6", "aln": "MERGAVRELAARLGLGE-PRVVRYRGAGLGSKEGVAGGACPACTGPGTRGGTRTRLRCHLRVTAVFCRKAEEYLRLSQVKCAGLTAHVTATGLAVMCLELAARCAKHPAAKSSFVKLSGLNRTAYQSSMQALECLLGLNARLGMRDLAVRFCCTEAVKAASEILQR----YESSLPEAQQIDLDFSKPLFITAALFTACRCLKLKVDKAKMLAISGVKKAIFDRLCNQMEKISQQLS---KDDIPLAAETSETLQTDLEQREEEGSE---------DYDEIPCKQPK-TETKQDYEEWKRRILENAAKAQETNSGSVSIVPPCNITTACS-------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9Y1B2-1", "uniprot_id": "ORC6_DROME", "id": "Q9Y1B2-1", "name": "Origin recognition complex subunit 6", "aln": "-MTTLIEQLITKMGLREEPNVLE---------------------------------------------KTTELVRLLELRSTNVPLQINEYGKIVLCADLASCMIGIAFDKEQALKLSGLRKSQYLNNKRMFEKLLDLNKLASVNDICVQLGLNEVARKAEELMTL----FKG-VAATEDMGTDTSHPQYATMAVFQACRLLKKKVSKSKLMPFSNLRPSQFQLLEQQWERMIAKHH---KESKVPSS-------TDMEGKLKENQN---------ENIKGHEAKKAHKPPPEDYEIWKARMLAKAQAKLKELEASQSHMDSQLLEA----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9ZVH3-1", "uniprot_id": "ORC6_ARATH", "id": "Q9ZVH3-1", "name": "Origin of replication complex subunit 6", "aln": "---MDISDIGRKLSLDNNKLLIR---------------------------------------------KAAEIRRLCDAQFDSSIIGVGEICKAVICLEIAATRLQIIFDRQAAVKLSGMSEKAYSRSFNSLQNVIGIKIKLNVRELAVQFGCVRVIKSVQNVLSSYKERFLASLPASRRANADFTRPVFTAAAFYLCAKKQKLKVDKLRLIEVCGTSESEFSCVSTSMTDLCFDCVGISKEKKDAKDVKGNRDLLDVLPGKRRLEDG-----GYSSGDESSCYKRHKKMEEAKYEDWKSTVVNSIKKNPEKGTKRVIQASLNFPKKSETKELQVDS", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ::.: : ::. *: * ** : . *:* ::*: : :****: . * . :: ::.:: .:.::.*:: .. . :: : . :. :. . * ::* : : *. ..: * **.: :: .. : *. : . : . :: . .. . : .** ** :: . ", "identical_positions": 24, "similar_positions": 80, "identity": "7.12%" }, { "cls_id": "homologset.oma.820559", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q62885-1", "uniprot_id": "U119A_RAT", "id": "Q62885-1", "name": "Protein unc-119 homolog A", "aln": "MKVK---------KGGGGTGPGAEPVPGASNRSVEPTREPGAEAESGSESEPEPGPGPRLGPLQGKQPIGPEDVLGLQRITGDYLCSPEENIYKIDFVRFKIRDMDSGTVLFEIKKPP----------------VSERLPINRRDLDPNAGRFVRYQFTPAFLRLRQVGATVEFTVGDKPVNNFRMIERHYFRNQLLKSFDFHFGFCIPSSKNTCEHIYDFPPLSEELISEMIRHPYETQSDSFYFVDDRLVMHNKADYSYSGTP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2R6-1", "uniprot_id": "U119A_MOUSE", "id": "Q9Z2R6-1", "name": "Protein unc-119 homolog A", "aln": "MKVK---------KGGGGTGSGAEPVPGASNRSAEPTREPGAEAESGSESEPEPGPGPRLGPLQGKQPIGPEDVLGLQRITGDYLCSPEENIYKIDFVRFKIRDMDSGTVLFEIKKPP----------------VSERLPINRRDLDPNAGRFVRYQFTPAFLRLRQVGATVEFTVGDKPVNNFRMIERHYFRNQLLKSFDFHFGFCIPSSKNTCEHIYDFPPLSEELISEMIRHPYETQSDSFYFVDDRLVMHNKADYSYSGTP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3SYR2-1", "uniprot_id": "U119A_BOVIN", "id": "Q3SYR2-1", "name": "Protein unc-119 homolog A", "aln": "MKVK---------KGGGGAGTGAEHAPGASGPNVEPKPELQAESESGSESEPEAGPGPRPGPLQRKQPIGPEDVLGLQRITGDYLCSPEENIYKIDFVRFKIRDMDSGTVLFEIKKPP----------------ASERLPINPRDLDPNAGRFVRYQFTPAFLRLRQVGATVEFTVGDKPVNNFRMIERHYFRNQLLKSFDFHFGFCIPSSKNTCEHIYDFPALSEELINEMIRHPYETQSDSFYFVDDRLVMHNKADYSYSGTP--", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q13432-1", "uniprot_id": "U119A_HUMAN", "id": "Q13432-1", "name": "Protein unc-119 homolog A", "aln": "MKVK---------KGGGGAGTATESAPGPSGQSVAPIPQPPAESESGSESEPDAGPGPRPGPLQRKQPIGPEDVLGLQRITGDYLCSPEENIYKIDFVRFKIRDMDSGTVLFEIKKPP----------------VSERLPINRRDLDPNAGRFVRYQFTPAFLRLRQVGATVEFTVGDKPVNNFRMIERHYFRNQLLKSFDFHFGFCIPSSKNTCEHIYDFPPLSEELISEMIRHPYETQSDSFYFVDDRLVMHNKADYSYSGTP--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9XYQ2-1", "uniprot_id": "UN119_DROME", "id": "Q9XYQ2-1", "name": "Protein unc-119 homolog", "aln": "MSVVGKQLNPVQSSGAGAVTTSSSAAAGSSSSNSGVEANGGSGGSSGAAAAGAGASGDAKRPAE-SSSVTPDEVLHLTKITDDYLCSANANVFEIDFTRFKIRDLESGAVLFEIAKPPSEQYPEGLSSDETMLAAAEKLSLDDT-ADPNAGRYVRYQFTPAFLNLKTVGATVEFTVGSQPLNNFRMIERHFFRDRLLKTFDFEFGFCFPFSKNTVEHIYEFPNLPPDLVAEMISSPFETRSDSFYFVGNRLVMHNKADYAYDGGNIV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.* .*.*.. ..:. ..*.*. . : : ..**: : ..* * : ...: *::** * :**.*****.: *:::***.******::**:***** *** .:*:*.:: ******:**********.*: **********.:*:*********:**::***:***.****:* **** ****:** *. :*: *** *:**:*******.:**********:*.* ", "identical_positions": 130, "similar_positions": 68, "identity": "48.69%" }, { "cls_id": "homologset.oma.820560", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K351-1", "uniprot_id": "A0A0G2K351_RAT", "id": "A0A0G2K351-1", "name": "", "aln": "MSGSNPKATTAGSQAGPGGLVAGKEEKKKAGGGVLNRLKARRQGPPHTSDDGPGTAVTEQELLALDTIRPEHVLRLNRVTENYLCKPEDNVYSIDFTRFKIRDLETGTVLFEIAKPCISDQDQDTEEESVDVDISVGRFVRYQFTPAFLRLRTVGATVEFTVGDRPVTGFRMIERHYFRERLLKTFDFDFGFCIPSSRNT--------------FRLMIENPYETRSDSFYFVDNKLIMHNKADYAYNGGQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C4B4-1", "uniprot_id": "U119B_MOUSE", "id": "Q8C4B4-1", "name": "Protein unc-119 homolog B", "aln": "MSGSNPKAATAGSQAGPGGLVAGKEEKKKAGGGVLNRLKARRQGPPHTPDDGSGAAVTEQELLALDTIRPEHVLRLNRVTENYLCKPEDNVYSIDFTRFKIRDLETGTVLFEIAKPCISDQDQDAEEESVDVDISVGRFVRYQFTPAFLRLRTVGATVEFTVGDRPVTGFRMIERHYFRERLLKTFDFDFGFCIPSSRNTCEHIYEFPQLSEDVIRLMIENPYETRSDSFYFVDNKLVMHNKADYAYNGGQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NIH7-1", "uniprot_id": "U119B_HUMAN", "id": "A6NIH7-1", "name": "Protein unc-119 homolog B", "aln": "MSGSNPKAAAAASAAGPGGLVAGKEEKKKAGGGVLNRLKARRQAPHHAADDGVGAAVTEQELLALDTIRPEHVLRLSRVTENYLCKPEDNIYSIDFTRFKIRDLETGTVLFEIAKPCVSDQEEDEEEGGGDVDISAGRFVRYQFTPAFLRLRTVGATVEFTVGDKPVSNFRMIERHYFREHLLKNFDFDFGFCIPSSRNTCEHIYEFPQLSEDVIRLMIENPYETRSDSFYFVDNKLIMHNKADYAYNGGQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********::*.* *****************************.* *:.*** *:*********************.*************:**************************:***::* ** . *****.****************************:**:.***********:***.*************** :**********************:*************", "identical_positions": 210, "similar_positions": 21, "identity": "83.67%" }, { "cls_id": "homologset.oma.820562", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q90Z08-1", "uniprot_id": "U119B_DANRE", "id": "Q90Z08-1", "name": "Protein unc-119 homolog B", "aln": "MNSQSSRNETAATAVNGSDSAAASRDHKSGGGVLKRLKSRRNQVDRRP-----VTEEELRALGRDITPDEVLGLRAVARDYLCKLEDNIYNIDFTRFKIRDLETGTVLFEIAKPPHCDLDEED-DENRDADTSAGRFVRYQFTPAFLKLRTVGATVEFTVGDQPVTNFRMIERHYFQDRLLKSFDFDFGFCIPNSRNTCEHIYEFPQLPEDLIRLMIEHPYETRSDSFYFVDNKLIMHNKADYAYNGGQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8V0ZK85-1", "uniprot_id": "A0A8V0ZK85_CHICK", "id": "A0A8V0ZK85-1", "name": "", "aln": "MSG--SR----ARAAAGPDKKPPP----GSGGALSRLRGRRGSADAAPRPGAPWTESELLEL-ETVRPEHVLGLCRVTENYLCKPEDNIYNIDFTRFKIRDLETGTVLFEIAKPSAAEQDNEDEDDSGELDSSAGRFVRYQFTPAFLRLRTVGATVEFTVGEKPVSNFRMIERHYFRDRLLKNFDFDFGFCIPSSRNTCEHIYEFPQLSEDLIRLMVENPYETRSDSFYFVDNKLIMHNKADYAYNGGQ", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. ** * *. *.*. ... ..**.*.**:.**...* * **.** * . : *:.**** *:.:**** *****************************. .: *:** *:. : *:***************:*************::**:**********:*****.**********.**************.*******:*:******************************", "identical_positions": 172, "similar_positions": 43, "identity": "69.08%" }, { "cls_id": "homologset.oma.820585", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJK3-1", "uniprot_id": "D3ZJK3_RAT", "id": "D3ZJK3-1", "name": "Histone deacetylase complex subunit SAP30L", "aln": "MN-GFSTEEDSREGPPAAP-AAAPGYGQSCCLIADGERCVRPAGNASFSKRVQKSISQKKLKLDIDKSVRHLYICDFHKNFIQSVRNKRKRKTSDDGGDSPEHDADIPEV-DLFQLQVNTLRRYKRHYKLQTRPGFNKAQLAETVSRHFRNIPVNEKETLAYFIYMVKSNRSRLDQKPEGSKQLE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SQF8-1", "uniprot_id": "SP30L_MOUSE", "id": "Q5SQF8-1", "name": "Histone deacetylase complex subunit SAP30L", "aln": "MN-GFSTEEDSREGPPAAP-AAAPGYGQSCCLIADGERCVRPAGNASFSKRVQKSISQKKLKLDIDKSVRHLYICDFHKNFIQSVRNKRKRKASDDGGDSPEHDADIPEV-DLFQLQVNTLRRYKRHYKLQTRPGFNKAQLAETVSRHFRNIPVNEKETLAYFIYMVKSNRSRLDQKSEGSKQLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HAJ7-1", "uniprot_id": "SP30L_HUMAN", "id": "Q9HAJ7-1", "name": "Histone deacetylase complex subunit SAP30L", "aln": "MN-GFSTEEDSREGPPAAPAAAAPGYGQSCCLIEDGERCVRPAGNASFSKRVQKSISQKKLKLDIDKSVRHLYICDFHKNFIQSVRNKRKRKTSDDGGDSPEHDTDIPEV-DLFQLQVNTLRRYKRHYKLQTRPGFNKAQLAETVSRHFRNIPVNEKETLAYFIYMVKSNKSRLDQKSEGGKQLE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A287ABA7-1", "uniprot_id": "A0A287ABA7_PIG", "id": "A0A287ABA7-1", "name": "Histone deacetylase complex subunit SAP30L", "aln": "MN-GFSTEEDSREGPPAAP-AAAPGYGQSCCLIEDGERCVRPAGNASFSKRVQKSISQKKLKLDIDKSVRHLYICDFHKNFIQSVRNKRKRKTSDDGGDSPEHDTDIPEV-DLFQLQVNTLRRYKRHYKLQTRPGFNKAQLAETVSRHFRNIPVNEKETLAYFIYMVKSNKSRLDQKSEGGKQLE", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "F1MFL5-1", "uniprot_id": "F1MFL5_BOVIN", "id": "F1MFL5-1", "name": "Histone deacetylase complex subunit SAP30L", "aln": "MN-GFSTEEDSREGPPAAP-AAAPGYGQSCCLIEDGERCVRPAGNASFSKRVQKSISQKKLKLDIDKSVRHLYICDFHKNFIQSVRNKRKRKTSDDGGDSPEHDTDIPEV-DLFQLQVNTLRRYKRHYKLQTRPGFNKAQLAETVSRHFRNIPVNEKETLAYFIYMVKSNKSRLDQKSESGKQLE", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q6NYV5-1", "uniprot_id": "SP30L_DANRE", "id": "Q6NYV5-1", "name": "Histone deacetylase complex subunit SAP30L", "aln": "MN-GFSTEEDSHDGPPAPP-----FFGQSCCLIEDAERCGRPAGNASFSKRIQKSISQRKLKLDIDKSVRHLYICDFHKNFIQSVRNKRKRKTSDDGGESPDHEVEVPEV-DLFQLQVNTLRRYKRHYKIQTRPGLNKAQLAETVSRHFRNIPVNEKETLTYFIYMVKSSKSRLDQKSDSSKQVE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXB3-1", "uniprot_id": "SAP30_DROME", "id": "Q9VXB3-1", "name": "Histone deacetylase complex subunit SAP30 homolog", "aln": "MNNGFSTGEEDSRG----------HTDQTCCLIDDMERCRNQAGYASYSKRIQKTVAQKRLKLSSDPAAQHIYICDHHKERIQSVRTKRRRKDSED--DSNETDTDLHEFPDLYQLGVSTLRRYKRHFKVQTRQGMKRAQLADTIMKHFKTIPIKEKEIITFFVYMVKMGSNKLDQKNGLGNDTT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **** *:. * .*:**** * *** . ** **:***:**:::*::***. * :.:*:****.**: *****.**:** *:* :* : :.:: *. **:** *.********:*:*** *:::****:*: :**:.**::*** :::*:**** . .:**** .:: ", "identical_positions": 90, "similar_positions": 53, "identity": "48.65%" }, { "cls_id": "homologset.oma.820586", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A5G2QT00-1", "uniprot_id": "A0A5G2QT00_PIG", "id": "A0A5G2QT00-1", "name": "", "aln": "MNGFTPEDISRGGDAAAAVAAVVAAAAAAAASAGNGAGAGSGAEVPGAGAVSVAGPPGAAGPGPGQLCCLREDGERCSRAAGNASFSKRIQKSISQKKVKIELDKSARHLYICDYHKNLIQSVRNRRKRKGSDDDGGDSPVQDIDTPEVDLYQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFRSIPVNEKDTLTYFIYSVKNDKNKSDLKVDSGVH", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "E1B806-1", "uniprot_id": "E1B806_BOVIN", "id": "E1B806-1", "name": "", "aln": "MNGFTPEDMSRGGDAAAAVAAVVAAAAAAAS-AGNGAGAGAGAEVPGAGAVSAAGPPGAAGPGPGQLCCLREDGERCGRAAGNASFSKRIQKSISQKKVKIELDKSARHLYICDYHKNLIQSVRNRRKRKGSDDDGGDSPVQDIDTPEVDLYQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFRSIPVNEKDTLTYFIYSVKNDKNKSDLKVDSSVH", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "O75446-1", "uniprot_id": "SAP30_HUMAN", "id": "O75446-1", "name": "Histone deacetylase complex subunit SAP30", "aln": "MNGFTPDEMSRGGDAAAAVAAVVAAAAAAAS-AGNGTGAGTGAEVPGAGAVSAAGPPGAAGPGPGQLCCLREDGERCGRAAGNASFSKRIQKSISQKKVKIELDKSARHLYICDYHKNLIQSVRNRRKRKGSDDDGGDSPVQDIDTPEVDLYQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFRSIPVNEKDTLTYFIYSVKNDKNKSDLKVDSGVH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3HKY1-1", "uniprot_id": "G3HKY1_CRIGR", "id": "G3HKY1-1", "name": "", "aln": "MNGFTPEEMSRSGDAAAAVAAVVAAAAAAAS-AGNGNAAGGGAEVPGAGAVSAAGPPGAAGPGLGQLCCLREDGERCGRAAGNASFSKRIQKSISQKKVKIELDKSARHLYICDYHKNLIQSVRNRRKRKGSDDDGGDSPVQDIDTPEVDLYQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFRSIPVNEKDTLTYFIYSVKNDKNKSDLKVDSGVH", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "D3ZC08-1", "uniprot_id": "D3ZC08_RAT", "id": "D3ZC08-1", "name": "", "aln": "MNGFTPEEMSRGGDAAAAVAAVVAAAAAAAS-AGNGNAAGGGAEVPGAGAVSASGPPGAAGPGPGQLCCLREDGERCGRAAGNASFSKRIQKSISQKKVKIELDKSARHLYICDYHKNLIQSVRNRRKRKGSDDDGGDSPVQDIDTPEVDLYQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFKSIPVNEKDTLTCFIYSVRNDKNKSDLKADSGVH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88574-1", "uniprot_id": "SAP30_MOUSE", "id": "O88574-1", "name": "Histone deacetylase complex subunit SAP30", "aln": "MNGFTPEEMSRGGDAAAAVAAVVAAAAAAAS-AGNGNAAGGGAEVPGAGAVSASGPPGAAGPGPGQLCCLREDGERCGRAAGNASFSKRIQKSISQKKVKIELDKSARHLYICDYHKNLIQSVRNRRKRKGSDDDGGDSPVQDIDTPEVDLYQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFKSIPVNEKDTLTCFIYSVRNDKNKSDLKADSGVH", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:::**.******************: **** .** ***********.:********* *************.*************************************************************************************************************:*********** *****:*********.**.**", "identical_positions": 203, "similar_positions": 13, "identity": "91.86%" }, { "cls_id": "homologset.oma.820596", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y284-1", "uniprot_id": "ASTER_HUMAN", "id": "Q9Y284-1", "name": "PAT complex subunit Asterix", "aln": "-----MSTNNMSDPRRPNKVLR-YKPPPSECNP--ALDDPTPDYMNLLGMIFSMCGLMLKLKWCAWVAVYCSFISFANSRSSE-DTKQMMSSFMLSISAVVMSYLQNPQPMTPPW--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3HCV5-1", "uniprot_id": "G3HCV5_CRIGR", "id": "G3HCV5-1", "name": "PAT complex subunit Asterix", "aln": "-----MSTNNMSDPRRPNKVLR-YKPPPSECNP--ALDDPTPDYMNLLGMIFSMCGLMLKLKWCAWVAVYCSFISFANSRSSE-DTKQMMSSFMLSISAVVMSYLQNPQPMTPPW--", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q6ZWX0-1", "uniprot_id": "ASTER_MOUSE", "id": "Q6ZWX0-1", "name": "PAT complex subunit Asterix", "aln": "-----MSTNNMSDPRRPNKVLR-YKPPPSECNP--ALDDPTPDYMNLLGMIFSMCGLMLKLKWCAWVAVYCSFISFANSRSSE-DTKQMMSSFMLSISAVVMSYLQNPQPMTPPW--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2M2T6-1", "uniprot_id": "ASTER_BOVIN", "id": "Q2M2T6-1", "name": "PAT complex subunit Asterix", "aln": "-----MSANNMSDPRRPNKVLR-YKPPPSECNP--ALDDPTPDYMNLLGMIFSMCGLMLKLKWCAWVAVYCSFISFANSRSSE-DTKQMMSSFMLSISAVVMSYLQNPQPMTPPW--", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q9VRJ8-1", "uniprot_id": "ASTER_DROME", "id": "Q9VRJ8-1", "name": "Protein Asterix", "aln": "-------MNMTVDPRRKEKINR-YKAPKNQGQSGGANEDMMPDYMNILGMIFSMCGLMMKLKWCAWFALYCSCISFASSRASD-DAKQVLSSFMLSVSAVVMSYLQNPAAMTPPWAS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9SD88-1", "uniprot_id": "ASTER_ARATH", "id": "Q9SD88-1", "name": "Protein Asterix", "aln": "MSHSHGNASSVNDPRQPSAAKP-YIPRP------VAPEDLPVDYSGFIAVILGVSGVMFRYKICSWLAIIFCAQSLANMRNLENDLKQISMAMMFAIMGLVTNYLGPNRPATKK---", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q86H65-1", "uniprot_id": "ASTER_DICDI", "id": "Q86H65-1", "name": "Protein Asterix", "aln": "----------MSDPRKESLIVERFEMRAST-----EPKEGELELYSLFSIIFGFLGIMLKYKICLWVSAVCCVAYLSNLKSKDSSVRTILSPVSLSLMGLVMAYFGPNSNLFV----", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***: . : .: : .::.:*:.. *:*:: * * *.: . ::. : : . : : .. ::: .:* *: ", "identical_positions": 11, "similar_positions": 36, "identity": "9.4%" }, { "cls_id": "homologset.oma.820670", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A4F2-1", "uniprot_id": "A0A8I6A4F2_RAT", "id": "A0A8I6A4F2-1", "name": "Integrator complex subunit 9", "aln": "MKLYCLS---GHPTLPCNVLKFKSTTIMLDCGLDMTSTLNFLPLPLVQSPRLSNLPGWS-----------------LKDGNAFLDKELKECSGHVFVDS---VPEFCLPETELID-LSTVDVILISNYHCMMALPYITEHTGFTGTVYATEPTMQIGRLLMEELVNFIERVPKAQS---------ASLWKNKEIQRLLPSP------LKDAVEVSTWRRCYTMQEVNSALSKIQLVGYSQKIELFGAVQVTPLSSGYALGSSNWIIQS-HYEKVSYVSGSSL-LTTHPQPMDQASLKNSDVLILTGLTQIP--------TANPDG---------------------------MVGEFCSNLALTVRNGGNVLVPCYPSGVIYDLLECLYQYIDSAGLSNIPFYFISPVANSSLEFSQIFAEWLCHNKQSKVYLPEPPFPHAELIQTNKLKHYRSIHGD-----FSHDFRQPCVLFTGHPSLRFGDVVHFMELWGKSSLNTVIFTEPDFSYLEALAPYQPLAMKCIYCPIDTRLNFIQVSKLLKEVQPLHVVCPEQYTQPPPAQSHRMDLMIDCQ-PPAMSYRR------------AEVLALPFKRRYEKIEIMPELADSLVPMEIKPG--ISLATVSAVLHTKDNKHVLQPPPKPTQ-PTSSKKRKRVSEDVPDSKVLKPLLSG---SIPVEQFVQTLEKHGFSDIKVEDTAKGHIVLLQEAETLIQIEEDSTHIICDNDETLRFCAPRQLWMTAW---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K114-1", "uniprot_id": "INT9_MOUSE", "id": "Q8K114-1", "name": "Integrator complex subunit 9", "aln": "MKLYCLS---GHPTLPCNVLKFKSTTIMLDCGLDMTSTLNFLPLPLVQSPRLSNLPGWS-----------------LKDGNAFLDKELKECSGHVFVDS---VPEFCLPETELID-LSTVDVILISNYHCMMALPYITEHTGFTGTVYATEPTMQIGRLLMEELVNFIERVPKAQS---------ASLWKNKDIQRLLPSP------LKDAVEVSTWRRCYTMQEVNSALSKIQLVGYSQKIELFGAVQVTPLSSGYALGSSNWIIQS-HYEKVSYVSGSSL-LTTHPQPMDQASLKNSDVLILTGLTQIP--------TANPDG---------------------------MVGEFCSNLALTVRNGGNVLVPCYPSGVIYDLLECLYQYIDSAGLSNIPFYFISPVANSSLEFSQIFAEWLCHNKQSKVYLPEPPFPHAELIQTNKLKHYRSIHGD-----FSNDFRQPCVLFTGHPSLRFGDVVHFMELWGKSSLNTIIFTEPDFSYLEALAPYQPLAMKCIYCPIDTRLNFIQVSKLLKEVQPLHVVCPEQYTQPPPAQAHRMDLMIDCQ-PPAMSYRR------------AEVLALPFKRRYEKIEIMPELADSLVPMEIKPG--ISLATVSAVLHTKDNKHVLQPPPKPTQ-PTSSKKRKRVNEDIPDCKVLKPLLSG---SIPVEQFVQTLEKHGFSDIKVEDTAKGHIVLLQEAETLIQIEEDSTHIICDNDETLRVRLRDLVLRFLQKF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NV88-1", "uniprot_id": "INT9_HUMAN", "id": "Q9NV88-1", "name": "Integrator complex subunit 9", "aln": "MKLYCLS---GHPTLPCNVLKFKSTTIMLDCGLDMTSTLNFLPLPLVQSPRLSNLPGWS-----------------LKDGNAFLDKELKECSGHVFVDS---VPEFCLPETELID-LSTVDVILISNYHCMMALPYITEHTGFTGTVYATEPTVQIGRLLMEELVNFIERVPKAQS---------ASLWKNKDIQRLLPSP------LKDAVEVSTWRRCYTMQEVNSALSKIQLVGYSQKIELFGAVQVTPLSSGYALGSSNWIIQS-HYEKVSYVSGSSL-LTTHPQPMDQASLKNSDVLVLTGLTQIP--------TANPDG---------------------------MVGEFCSNLALTVRNGGNVLVPCYPSGVIYDLLECLYQYIDSAGLSSVPLYFISPVANSSLEFSQIFAEWLCHNKQSKVYLPEPPFPHAELIQTNKLKHYPSIHGD-----FSNDFRQPCVVFTGHPSLRFGDVVHFMELWGKSSLNTVIFTEPDFSYLEALAPYQPLAMKCIYCPIDTRLNFIQVSKLLKEVQPLHVVCPEQYTQPPPAQSHRMDLMIDCQ-PPAMSYRR------------AEVLALPFKRRYEKIEIMPELADSLVPMEIKPG--ISLATVSAVLHTKDNKHLLQPPPRPAQ-PTSGKKRKRVSDDVPDCKVLKPLLSG---SIPVEQFVQTLEKHGFSDIKVEDTAKGHIVLLQEAETLIQIEEDSTHIICDNDEMLRVRLRDLVLKFLQKF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5ZKK2-1", "uniprot_id": "INT9_CHICK", "id": "Q5ZKK2-1", "name": "Integrator complex subunit 9", "aln": "MKLYCLS---GHPTLPCNVLKFKSTTIMLDCGLDMTSTLNFLPLPLVQSPRLSKLPGLV-----------------LKDGSTFLDKELKECSGHVFVDS---VPEFCLPETELLD-LSTVDVILISNYHCMMALPYITEYTGFTGTVYATEPTVQIGRLLMEELVNSIERVPKAQS---------ASTWKNKEVQRLLPAP------LKDAVEVSMWRKCYTMPEVNAALSKIQLVGYSQKIELFGAVQVTPLSSGYALGSSNWIIQS-HYEKVSYVSGSSL-LTTHPQPMDQASLKNSDVLILTGLTQIP--------TANPDG---------------------------MVGEFCSNLAMTVRNGGNVLVPCYPSGVIYDLLECLYQYIDSAGLSNVPFYFISPVANSSLEFSQIFAEWLCHNKQTKVYLPEPPFPHAELIQTNKLKHYPSIHGD-----FSNDFKQPCVIFTGHPSLRFGDVVHFMELWGKSSLNTVIFTEPDFSYLDALAPYQPLAMKCVYCPIDTRLNFIQVSKLLKEVQPLHVVCPEQYTQPPPSQSHRTDLMIDCQ-PPPMSYRR------------AEVLTLPYKRRYEKIEIMPELADSLVPLEIKPG--ISLATVSAMLHTKDNKHVLQLPPKPPQ-PPTSKKRKRVSDDVPECKPLKPLLSG---SIPVDQFVQTLEKHGFSDVKVEDTAKGHIVLLQEAETLIQIEEDSTHIICDNDEPLRVKLRDLVLKFLQKF-", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q95TS5-1", "uniprot_id": "INT9_DROME", "id": "Q95TS5-1", "name": "Integrator complex subunit 9", "aln": "MRLYCLS---GDLAKPCYIITFKGLRIMLDCGLTEQTVLNFLPLPFVQSLKWSNLPNFVP----------------SRDHDPQMDGELKDCCGRVFVDS---TPEFNLPMDKMLD-FSEVDVILISNYLNMLALPYITENTGFKGKVYATEPTLQIGRFFLEELVDYIEVSPKACT---------ARLWKEK--LHLLPSP------LSEAFRAKKWRTIFSLKDVQGSLSKVTIMGYDEKLDILGAFIATPVSSGYCLGSSNWVLST-AHEKICYVSGSST-LTTHPRPINQSALKHADVLIMTGLTQAP--------TVNPDT---------------------------KLGELCMNVALTIRNNGSALIPCYPSGVVYDLFECLTQNLENAGLNNVPMFFISPVADSSLAYSNILAEWLSSAKQNKVYLPDDPFPHAFYLRNNKLKHYNHVFSEG----FSKDFRQPCVVFCGHPSLRFGDAVHFIEMWGNNPNNSIIFTEPDFPYLQVLAPFQPLAMKAFYCPIDTSLNYQQANKLIKELKPNVLVIPEAYTKPHPSAPN---LFIEQPDKKIITFKC------------GEIIRLPLKRKLDRIYITSELAQKISPKEVAAG--VTFSTLTGVLQVKDKVHCIQPCADSVKDETISSNSAPTKEDVLKN---VKYEYG---SIDVDAVMKKLAQDGFSNIKLDRTGGALTLNLVNEDTVIKFEDNETHIICGGKPTTRLKLRDTIMKCLQSF-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q54SH0-1", "uniprot_id": "INT9_DICDI", "id": "Q54SH0-1", "name": "Integrator complex subunit 9 homolog", "aln": "MKVHCLS---QSAQSPCFLLEYKNVKILLDCALEISSILHFLPKNLNYNNNNNNNNNNNNNNNNNNNNNNNNNSYSFKEKDKELNQFFKNINGTLYIDNGCSNIKYNCPQFEMIDDFSTIDMILISNYTNIYALPFITEYTNFQGKIYATEPTVQIGKLLLEELVQMDKQYSNSSINNNNNNNNLSDCWQNIEILEKLNVHNVGMENENLYRDSYRWKDLYKKIDIEKSFEKIQSIRFNESIKHYG-FECIPSSSGYGLGSANWVIESKGFERVVYISDSSLSLSRYPTPFQLSPIDNPDVLILSKINHYP--------NNPPDQ---------------------------MLSELCSNIGSTLQQGGTVLIPSYSCGIILDLFEHLADYLNKVGLPYVPIYFVSSVSKAVLSYADIYSEWLNKSKQERAFMPETPFLHQDLMRKGQFQAYQHVHSN-------FQANDPCIIFTGHPSCRIGDITTLIKLYD-NPKNSILLIEPDFDFKSTVLPFSKQISRIQFLPIDPRINFNEANLLISKLSPKHLIIPRIYKNYVKNKHSNGNFGIVTTILPLDTIKIQNNQNFESGFIDKELAQTIQTKVLDKSSQLKNNTTTTTTTTINNQQPIHVAEISGVLSMSDHELIISPPNISDSNKIIHIKEKFIWGTLSIENIIKAINSTKQFKNNGDSIEYFEINENYYLIKISSKNKTNNNNNSDQVTNIHLSPQNVNIETSCETTRRLISDIVLLNCNGFYV", "tax_id": 44689, "tax_name": "Social amoeba" }, { "uniprot_ac": "A0A1I9LM22-1", "uniprot_id": "A0A1I9LM22_ARATH", "id": "A0A1I9LM22-1", "name": "", "aln": "MELTCLSKGDGFHYPPCHMLNLCGFRILIDCPLDLSAIKIFSPVPSGVGSEASEYLSDE-----------------SLDAQNPIQKKQKLERQLTCADLVCEEPWYKTVKALHLWEASFIDIVLISNPMGLLGLPFLTQNPGFFAKIYMTEVTAKIGQLMMEDIVSMHKEFRCFHGPDNSS----FPGWIKNLDSEQVPALLKKVVFGESGDDLGSWMRLYSLDDIESCMKKVQGVKFAEEVCYNGTLIIKALSSGLDIGACNWLING-PNGSLSYVSDSIF-VSHHARSFDFHGLKETDVLIYSDFSSLQSAEVTEDGCISPDSDNNYISTISSDNKDSLLNTEDSLEEMEKLAFVCSCAAESADAGGSTLITITRIGIVLQLLELLSNSLESSSLK-VPIFVISSVAEELLAYTNTIPEWLCEQRQEKLISGEPSFGHLKFIKNKKIHLFPAIHSPNLIYANRTSWQEPCIVFASHWSLRLGPSVQLLQRWRGDPKS-LLVLEDGISSGLGLLPFRPIAMKILQCSFLSGIRLQKLPTLVSVLQPKIFLVPDAVNQRIS-------LAAIKTISILNYFEN-------------KTLHVPRIVDNPSVEITTDLASKLSWRKLRQRESFGIARLKGGLLMEDGKHRLVSGLEQEE-SSGKARPLRHWGSVAPELLLDALLKMG-IKGSIEQSTGDNGSEDKSIIHIENPNSG----------LIEFSEMGTAIITGDENVVSQVFQAIDGVLDGI--", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: *** ** :: . *::** * : * * . . .: . : . :: * * : : * :*::**** : .**::*: ..* ..:* ** * :**::::*::*. : * : . : . * :. ::: .:.*: : : :.: * . . *** :*:.**::. : *:*.* :: :. .:: :...***: : :. ** :. .* . : .*..*:. *:: :*:* * : ::. .* :*::.:*.*:. * ::: .*** :* : : .* * ::. ::: : :.. . .:**::* .* * *:* . ::: : .. . ::. * .: : *: : .: . :. : *:. :.* .: * .: : . : : : . : . .: :.. * .* : . . : . : ... :::. *.:. . * . . ", "identical_positions": 84, "similar_positions": 200, "identity": "11.07%" }, { "cls_id": "homologset.oma.820915", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q14802-1", "uniprot_id": "FXYD3_HUMAN", "id": "Q14802-1", "name": "FXYD domain-containing ion transport regulator 3", "aln": "MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAKCKCKFGQKSGHHPGETPPLITPGSAQS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61835-1", "uniprot_id": "FXYD3_MOUSE", "id": "Q61835-1", "name": "FXYD domain-containing ion transport regulator 3", "aln": "MQEVVLSLLVLLAGLPTLDANDPENKNDPFYYDWYSLRVGGLICAGILCALGIIVLMSGKCKCKFRQKPSHRPGEGPPLITPGSAHNC", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*.*.***:***:*.***** *:**.******:**:********:***:***::**.****** **..*:*** *********:. ", "identical_positions": 64, "similar_positions": 20, "identity": "72.73%" }, { "cls_id": "homologset.oma.820952", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M8H5-1", "uniprot_id": "A0ABK0M8H5_RAT", "id": "A0ABK0M8H5-1", "name": "Protein Jumonji", "aln": "MPPPFSVQFSCRHINNLLSDCLPSPSAPAGVRLSYCLAESALPLAYYVLGRIVDKCSGACLTAFSLPPSPPLSFFLCLCNDPALRMAAPRVCQVQFLVAYLEEPGIEGLLGNDQSKALGPASEQSENEKDDASQVSSTSNDVSSSDFEEGPSRKRPRLQAQRKFAQSQPNSPSTTPVKTVEPLLPPPATHISDLSKRKPKTEDFLTFLCLRGSPALPNSMVYFGSSQDEEDVEEEDDETEDVKTATNNASSSCQSTPRKGKSHKHVHNGHVFNGSNRSAREKEPAQKHRGREATPGKEKHSEHRADGRREQASVAQPTANPPAGSSTKGLAASHQPPPSHRSAQDSRKQVSKVNGVTRMSSLGAGTNSAKKIREVRPSPSKTVKYTATVTKGTVTYTKAKRELVKETKPSHHKP---------SSAVNH---------------TISGKSESSNAKTRKQVLSLGGASTSTAPAASGLKASSRLNPKSCTK--EVGGR------QLREGLRNSKRR----------LEEAQQVDKQQSPPKKMKGTAG-IAEAPGRKAS----------AASGEKSLLNGHVKKEVPERS--------------------LERNRPKRAAAGKNMLGKQAHGKSEG-TPCENRSTSQP---------ESSHKP-----HDPQGKPEKGSGKSGWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKYGMCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLRSQGITMDELPLIG----------------GCELDLACFFRLINEMGGMQQVTDLKKWNKLADMLRIPKTAQDRLAKLQEAYCQYLLSYDSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTENDHHKFHSLPRFEPKNGLIHGVTPRNGFRSKLKEVGRAPLKTGRRRLFAQEK-------EVVKEEEEDKGVLDDFYKCIYKGRSVSLTTFYRTARNIMNMCFSKEPAPAEIEQEYWRLVEEKDCHVAVHCGKVDTNTHGSGFPVGKSEPFSRHGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMVFSTSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEENKLEDVVHTLLQGNGTPGLQMLESNVMISPEVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYNVSETVHFATTQWTSMGFETAKEMKRRHIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEAGLHSSARYGSHDGSSAVADGKKKPRKWLQLETSERRCQICQHLCYLSMVVQENENVVFCLECALRHVEKQKSCRGLKLMYRYDEEQIISLVNQICGKVSGKHGG-IENCLN--KPTPKRGPRKRATVDVPPSRLPSS----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A3Q1M6R9-1", "uniprot_id": "A0A3Q1M6R9_BOVIN", "id": "A0A3Q1M6R9-1", "name": "Protein Jumonji", "aln": "-------------------------------------------------------------------------------------MAAPRVCQVQFLVAYLEEPGIEGLLGNGQSKGLGPASEQSENEKDDASQVSSTSNDVSSSDFEEGPSRKRPRLQAQRKFAQSQPNSPSTTPVKIVEPLLPPPATQISDLSKRKPKTEDFLTFLCLRGSPALPNSMVYFGSSQDEEDVEEEDDETEDVKAATNNASSSCQSTPRKGKAHKHVHNGHVFNGSSRSSREKDPVQKHKSKEATPAKEKHSDARADARREQVSASHPPAAPAAGSSAKGLAAHHHHPALHRSAQDLRKQVSKVNGVTRMSSLGTSATSAKKMREVRPSPSKTVKYTATVTKGTVTYTKAKRELVKETKPHHHKP---------SSAVNH---------------TISGKTESSNAKTRKQVLSLGGASKSTGPAVNGLKVSGRLNPKSCTK--EVGGR------QLREGLRNSKRR----------LEEVPPADKPQSPPKKMKGAAGSAAEGPGRKAA----------PGPAEKAPLGAPGKKEAPERS--------------------LERNRPKRAAAGKGPPGRQAHGKPDGGAPCENRSTSQS---------EPLPRP-----HEGAAKAEKGAGRAGWAAMDEIPVLRPSAKEFHDPLVYIESVRPQVEKYGMCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLRSQGITMDELPLIG----------------GCELDLACFFRLINEMGGMQQVTDLKKWNKLADMLRIPRTAQDRLAKLQEAYCQYLLSYDSLSPEEHRRLEKEVLMEKESLERRKGPLEGHTEQDYHRFHPLPRFEPKNGLINGVAHRNGFRSKLKEVGPAQLKTGRRRLFAQEK-------EVVKEEEEDKGILSDFHKCIYKGRSVSLTTFYRTARNIMNMCFSKEPAPAEIEQEYWRLVEEKDCHVAVHCGKVDTNTHGSGFPVGKSEPFSRHGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMVFSTSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEEHKLEDVVHTLLQANGTPGLQMLESNVMISPEVLCREGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFETAKEMKRRHIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEAGLHSSARYGSHDGSSAAPDGKKKPRKWLQLETSERRCQVCQHLCYLSMVVQENENVVFCLECALRHVEKQKSCRGLKLMYRYDEEQIISLVNQICGKVSGKNGS-IENCLS--KPTPKRGPRKRATVDVPPSRLASS----------", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q62315-1", "uniprot_id": "JARD2_MOUSE", "id": "Q62315-1", "name": "Protein Jumonji", "aln": "--------------------------------------MSKERPKRNIIQKKYDDSDG-------IPWSEERVVRKVLYLSLKEFKNAQKRQHGEGLAGSLK--AVNGLLGNAQAKALGPASEQSENEKDDASQVSSTSNDVSSSDFEEGPSRKRPRLQAQRKFAQSQPNSPSTTPVKIVEPLLPPPATQISDLSKRKPKTEDFLTFLCLRGSPALPNSMVYFGSSQDEEDVEEEDDETEDVKATTNNASSSCQSTPRKGKTHKHVHNGHVFNGSSRSAREKEPAHKHRSKEATPGKEKHSEPRADSRREQASGAQPTAASAAASSAKGLAANHQPPPSHRSAQDLRKQVSKVNGVTRMSSLGAGTNSAKKIREVRPSPSKTVKYTATVTKGTVTYTKAKRELVKETKPNHHKP---------SSAVNH---------------TISGKTESSNAKTRKQVLSLGGASKSTGPAASGLKASSRLNPKSCTK--EVGGR------QLREGLRNSKRR----------LEEAQQVDKPQSPPKKMKGVAG-NAEAPGKKAS----------AASGEKSLLNGHVKKEVPERS--------------------LERNRPKRAAAGKNMLGKQAHGKTEG-TPCENRSTSQP---------ESSHKP-----HDPQGKPEKGSGKSGWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKYGMCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLRSQGITMDELPLIG----------------GCELDLACFFRLINEMGGMQQVTDLKKWNKLADMLRIPKTAQDRLAKLQEAYCQYLLSYDSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTESDHHKFHSLPRFEPKNGLVHGVTPRNGFRSKLKEVGRAPLKTGRRRLFAQEK-------EVVKEEEEDKGVLNDFHKCIYKGRSVSLTTFYRTARNIMNMCFSKEPAPAEIEQEYWRLVEEKDCHVAVHCGKVDTNTHGSGFPVGKSEPFSRHGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMVFSTSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEENKLEDVVHTLLQGNGTPGLQMLESNVMISPEVLCKKGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYNVSETVHFATTQWTSMGFETAKEMKRRHIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRLLFEAGLHSSARYGSHDGNSTVADGKKKPRKWLQLETSERRCQICQHLCYLSMVVQENENVVFCLECALRHVEKQKSCRGLKLMYRYDEEQIISLVNQICGKVSGKHGG-IENCLN--KPTPKRGPRKRATVDVPPSRLPSS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92833-1", "uniprot_id": "JARD2_HUMAN", "id": "Q92833-1", "name": "Protein Jumonji", "aln": "--------------------------------------MSKERPKRNIIQKKYDDSDG-------IPWSEERVVRKVLYLSLKEFKNSQKRQHAEGIAGSLK--TVNGLLGNDQSKGLGPASEQSENEKDDASQVSSTSNDVSSSDFEEGPSRKRPRLQAQRKFAQSQPNSPSTTPVKIVEPLLPPPATQISDLSKRKPKTEDFLTFLCLRGSPALPNSMVYFGSSQDEEEVEEEDDETEDVKTATNNASSSCQSTPRKGKTHKHVHNGHVFNGSSRSTREKEPVQKHKSKEATPAKEKHSDHRADSRREQASANHPAAAPSTGSSAKGLAATHHHPPLHRSAQDLRKQVSKVNGVTRMSSLGAGVTSAKKMREVRPSPSKTVKYTATVTKGAVTYTKAKRELVKDTKPNHHKP---------SSAVNH---------------TISGKTESSNAKTRKQVLSLGGASKSTGPAVNGLKVSGRLNPKSCTK--EVGGRQLREGLQLREGLRNSKRR----------LEEAHQAEKPQSPPKKMKGAAG-PAEGPGKKAP----------AERG---LLNGHVKKEVPERS--------------------LERNRPKRATAGKSTPGRQAHGKADS-ASCENRSTSQP---------ESVHKP-----QD-SGKAEKGGGKAGWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLKSQGITMDELPLIG----------------GCELDLACFFRLINEMGGMQQVTDLKKWNKLADMLRIPRTAQDRLAKLQEAYCQYLLSYDSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTENDHHKFHPLPRFEPKNGLIHGVAPRNGFRSKLKEVGQAQLKTGRRRLFAQEK-------EVVKEEEEDKGVLNDFHKCIYKGRSVSLTTFYRTARNIMSMCFSKEPAPAEIEQEYWRLVEEKDCHVAVHCGKVDTNTHGSGFPVGKSEPFSRHGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMVFSTSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESNVMISPEVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFETAKEMKRRHIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEAGLHSSARYGSHDGSSTVADGKKKPRKWLQLETSERRCQICQHLCYLSMVVQENENVVFCLECALRHVEKQKSCRGLKLMYRYDEEQIISLVNQICGKVSGKNGS-IENCLS--KPTPKRGPRKRATVDVPPSRLSASSSSKSASSSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LVC2-1", "uniprot_id": "JARD2_DANRE", "id": "Q1LVC2-1", "name": "Protein Jumonji", "aln": "--------------------------------------MSKERPKRNIIQKKYDDNDG-------MPWSEERVVRKVLYLSLKEFKSAQKRQLCDGIDDEGK--GPNASLSNGQLN----GSKGGHKEDGSRSQRKDGGGEYS----VDGPAKKRPRLHAQRKFAQSQPNSPSNTPVKMADPSLPTPLTHITFLSRRKPKTEDFLTFICLRGSPALPSNMAYFGCSQDEEDLEDED-EIEEEKAPS-VASTSCQSTPKKGKPHGKIN-GLVLNG-HKVHKDKELTPRSKARESSVGRD-----RSERCDESEISHKHTAATAKSHNTNG----HN---YRRAAEELRKQVSKVNGLTRASSVGTHKASGKKQKDFR-LPSKTVKYTATVSKGHVTYTKAKRELVKKAKLNHSKHGASAGLRAYSNNHHHNSHHATSNGHGRPQLSHSGKAQSINAKTRKQVLLSNGVHKMT----NGSRLNGRLNGRHSAREEEVVDR------PVRQGLRNSKRRSDAMTLLGAVTESEETKTKQQTTEVKKAKVQPSPLETRSKKALNQFKSPNIVTIAHSITEMAASPIQKTGPAPPPSPPAAPASPSMPQNPAIPEPARQRPKRASAGKLMFIRKAQQRAQT-NPTLNRTTSTTSASKSFKPAEPTHTPPPRLDRDRERERERERSRARYAALGDVPIFKPSSREFQDPLVYLDSFREQVESCGLCRVLPPTDWRPECKLNDEMRFVTQVQRIHKLGRRWGPNVQKLACIKKHLKSQGISMDQPPVIGKSFKSSAFRSAFVCIGGCEVDLARFSELVCDLGGMQQVMDLKKWSRLADLLRIPKSAQDRLAKLQEAYLQFLLSYDLLSPEELQRLEQEVRAEKEALERKRGPLEGHSDNGHHSLA-LPRYEPKNGLN-GLSHRNGFRNHHKEP-DIQRQAGRRRLFAQEKKGEKVECEETEEEMEDEGVLSDQHKCIYKGRSVSLTTFYRIARNTMMMYFNKEPGAAEVEQDYWRIVEQRDCHVAVHYGKVDTNTHGSGFPVGKSEPFSKHGWNLTVLPNNSGSILRHLGAVPGVTIPWLNIGMVFSTSCWSQDQNRLPYIDYLHTGADCIWYSIPAEEKTKLDKVVHTLLQANGTPGLEMLEKNVMISPEVLCREGIKVHRTVQQSGQFVVVFPGAFVSRVCCGYSVSETVHFATPQWMNLGYEAAKDLKCRRIAKPFSMEKLLYQIATAEAKRENRLVLSTISSLLKDLRNIEMKQRQELYEAGLLSSARYCTHDHNQSPADTRKKPRKWLALESSERRCQMCQHLCYLSMVVQENENVVFCLECALHYVEKHKNCRGLKMMYRYDEEQINSLVNQVCGKALVRSGSEVCNGSSPIKPPAKRGPRKRESMKITLIPLPTHPSKSAAAAVS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : : :. *.* * : .*: ..:*... ** .. ..: * :**::*****:**************.**** .:* **.* *:*: **:***********:*********..*.***.*****::*:** * *: *:.: **:******:***.* ::: * *:** : ::*: . : :.:*:: .:: *:: *. : .* .. . .::* *: :*:*:: *********:** **:*: *.** ::.* ***********:** ************.:* * * *. :* : ***::* ********* .*. . * .* : ..*** : .:: ** .* :*:******** *. * *:. * . * .:** . . :* * . *:*****:*** ::*: :.: . **:** . *. * :: : *: .:: :**:.::*:::**::**:***:*::*.* ***. *:***:**.*****************:*:*************:********:****:**: *:** ***:*** * .*: ::****** *****.:***:****::************ *:***** ***** :***:** *** **:::******::..:* : ***:****** *:: *****.: ** ::********** * .:** **:*:*.* :**************** *** * * *.***..**:**:***:**::******* *********************:***********:******************************:***:****************.*****: **:.*******.******:***.**********::**************** ***:***:*****.*********.** .:*:*:**::* *:*************** ****:** .*****:**.:**: *::**: *:**** ***** :** ..: .* :******* **:******:*************************::***:*.*****:********* *****:***. : *. : * . **..******* ::.:. *.: ", "identical_positions": 700, "similar_positions": 271, "identity": "49.82%" }, { "cls_id": "homologset.oma.821221", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q66H52-1", "uniprot_id": "IPIL1_RAT", "id": "Q66H52-1", "name": "Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1", "aln": "--------MAVISLLFLAVMYVVHHPLMVSDRMDLDTLARSRQLEKRMSEEMRQLEIEFEERSRAAEEKQKAENFWRGDTSNDQLVLGKKDMRWPFQASGQDGGPLGWMLGNLWNAGLFCLFLIFELLRQNMQHEPAFESSSEEEEEEIRVVPVS--SYTWLSGFPSQEALESFYKHYIQNAIRDLPCTCEFVESFVDDLIEACRVLSRREAHPQLEDCLGIGAAFEKWGTLHETQKFDVLVPIVPPQGTMFILEMRDPTLGRRCGCVKVDSECVCKNEKLLGDVLCLVHH-RDHSAMLSKCTSSIKAALCTSSHLDVYKTVQWFRNMVSNAWALVAHKYDFKLTLPPSTTTCKLRLDYRSGRSLSISLVLGVQREDTLVYLVSQAPEREQFTSVDWPESFAACEHLFLKLVGRFAPDNTCHLKCLQIILSLQDHQTLPPGASRPILTSYHFKTALMHLLLRLPLTDWQHRMLSQRLQDLLWFLGRSLQQRSLHHFLIGNTHLPLTIPIPKAFRNAEPVNLFQHLVLNPVAHSQAVEEFHNLLAQVKTLPCSPLAGGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2ASA8-1", "uniprot_id": "IPIL1_MOUSE", "id": "A2ASA8-1", "name": "Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1", "aln": "--------MAVISLMFLAVMYVVHHPLMVSDRMDLDTLARSRQLEKRMSEEMRQLEMEFEERSRAAEQKQKVENFWRGDTSSDQLVLGKKDMGWPFQAGGQDGGPLGWILGNLWNAGLFCLFLIFELLRQSMQHEPAFESSSEEEEEEIRVVPVS--SYTRLSDFPSQEALEAFYKHYIQNAIRDLPCTCEFVESFVDDLIEACRVLSRREAHPQLEDCLGFGAAFEKWGTLHETQNFDVLVPIVPPQGTMFILEMRDPALGRRCGCVKVDSECMCKHEKLLGDVLCLVHH-RDHSAMLSKCTSSIKAALCTSSHLDVCKTVQWFRNMVSNAWALVAHKYDFKLTFPPSTTSCKLRLGYRSGRSLSISLVLGVQREDTLVYLVSQAPEQEQLTSVDWPESFAACEHLFLKLVGRFAPENTCHLKCLQIVLSLQDHQILPPGASRPILTSYHFKTALMHLLLRLPLTDWQHSMLSLRLQDLLWFLGRGLQQRSLHHFLIGNTYLPLTIPIPKAFRNAEPVNLFQHLVLNPVAHSQAVEEFHNLLAQVKTLPCSPVAGGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3H038-1", "uniprot_id": "G3H038_CRIGR", "id": "G3H038-1", "name": "", "aln": "--------MAVISLLFLAVMYVVHHPLMVSDRMDLDTLARSRQLEKRMTEEMRQLELEFEERRRAAEQKQKAENFWRGDTSSDQLVLGKKDMGWPFQAS--------WLMGNLWNAGLFCLFLIFELLRQNMQHEPAFDSSSEEEEEEIRIVPVTSYSYPWLSNFPSQEALESFYKHYIQNAIRDLPCTCEFVESFVDDLIEACRVLSRQEAHPRLEDCLGIGAAFEKWGTLHETHTFDVLVPIVPPQGTMFVLEMRDPALGRRSGCVKVDSKCMCKQEKLLGDVLCLVHHDRDHSAILSKCTGSIKAALCTGSHLDVCKAVQWFRNMVANAWALVAHKYNFKLTLPPSSTSCKLRLDYRSGRFLSISLVLGVQREDTLVYLVSQDPDREQLTSVDWPESFAACEHLFLKLVGRFAPENTCHLKCLQIILSLQDHQILPPGATRPILNTYHFKTALMHLLLRLPLTDWEHCMLSRRLQDLLWFLGQGLQQRSLHHFLIGNTFLPLTIPIPKTFRNAEPVNLFQHLVLNPIAHSQAMEEFHNLLAQVKTLPCSPLAGGL", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q6GPH6-1", "uniprot_id": "IPIL1_HUMAN", "id": "Q6GPH6-1", "name": "Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1", "aln": "MNVDAEASMAVISLLFLAVMYVVHHPLMVSDRMDLDTLARSRQLEKRMSEEMRLLEMEFEERKRAAEQRQKAENFWTGDTSSDQLVLGKKDMGWPFQADGQEG-PLGWMLGNLWNTGLFCLFLVFELLRQNMQHEPAFDSSSEEEEEEVRVVPVT--SYNWLTDFPSQEALDSFYKHYVQNAIRDLPCTCEFVESFVDDLIEACRVLSRQEAHPQLEDCLGIGAAFEKWGTLHETQKFDILVPIVPPQGTMFVLEMRDPALGRRCGCVLVESECVCKREKLLGDVLCLVHHHRDPSAVLGKCSSSIKAALCTGFHLDVCKTVQWFRNMMGNAWALVAHKYDFKLSLPPSTTSCKLRLDYRSGRFLSIHLVLGVQREDTLVYLVSQAPDQEQLTSVDWPESFVACEHLFLKLVGRFAPENTCHLKCLQIILSLRQHQSLPHGASRPILTSYHFKTALMHLLLRLPLTDWAHNMLSQRLQDILWFLGRGLQQRSLHHFLIGNNFLPLTIPIPKTFRNAEPVNLFQHLVLNPKAHSQAVEEFQNLLTQVKTLPHAPLAAAP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AAA9SYX3-1", "uniprot_id": "A0AAA9SYX3_BOVIN", "id": "A0AAA9SYX3-1", "name": "", "aln": "--------MAVISLLFLAVMYVVHHPLLVSDRMDLDTLARSRQLEKRMSEEMRQLELEFEERKRAAEEKQKAENFWRGDTSGDQLVLGKKDRGWPFQVDGQEG-PLGWMLGNLWNAGLFCIFLIFELLRQNMQHEPAFDSSSDDDEEEVRVVPIT--SYNWLTDFPSREALESFHKHHVQNVTRDLPCTCEFVESFVDDLIEACRVLSRREAHPQLEDCLGIGAAFEKWGTLHETQKFDILVPIIPPQGTMFVLEMRDPALGRRCGCVLVESECVCKREKLLGDVLCLVHHHRDHSALVGKSNSSIKAALCTGSHLDVYKTVQWFRNMVGNAWALVAHKYDFKLSLPLSTTCCKLRLDYRSGRFLSIRLVLGVQREDTLVYLVSQAPDQEQVTSVDWPESFAACEHLFLKLVGRFAPENTCHLKCLQIILSLRDLQSLPQGASRPILTSYHFKTALMHLLLRLPLTDWQHDMLSQRLQDILWFLGRGLQQRSLHHFLIGNTFLPLTIPIPKTFRNAEPVNLFQHLVLNPMAHSQAVEEFHNLLAQVKALPCSSLAGAR", "tax_id": 9913, "tax_name": "Bovine" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******:************:********************:**** **:***** ****::**.**** ****.********* ****.. *::*****:****:**:******.*******:***:::***:*:**:: ** *:.***:***::*:**::**. **************************:****:******:*************:.**:****:*******:******:****.*** *:*:*:**.************* ** **::.*...********. **** *:*******:.**********:***::* *:* *****.***** *** ***************** *::**.*********.***************:**********:***:: * ** **:****.:******************* * *** ****:*****:.*************..*********:***************** *****:***:***:***:** :.:*.. ", "identical_positions": 425, "similar_positions": 88, "identity": "76.16%" }, { "cls_id": "homologset.oma.821401", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8J8XFB8-1", "uniprot_id": "A0A8J8XFB8_RAT", "id": "A0A8J8XFB8-1", "name": "MPN domain-containing protein", "aln": "MAAPESLSST-ATAEEAPEEDEDEAETEDPER-------GTGSGGRSGSLGGSGGSTAGPG--LALGGALTRRAVTLRVLLKDELLEPGEGVLSIYYLGRKFIGDLKLDGRIVWQENGQVFNSPSAWATHCKKLVNPAKKSGCGWASVKYKGQKLDKYKAAWLRRHQLHMPVAAADESPTSEGEEEELLLEEEEEDVLAGVSSEYKGHRPPGKGSLE---PEATPPGKRVD-KVRVPVRYCMLGSRDSARSVTPSALVLASLEPLVGLIQQRNPHTLVEVTSFAAINKFQPFNVAVSSNVLFLLDFHCHLTRSEVVGYLGGRWDINNQMLTVLRAFPCRSRLGDPDTAATVEEEIHQVLFLRGLSLVGWYHSHPHSPAAPSLQDIDAQMEYQLRLQGSNNGFQPCLALLCSPYYSGNPGPESKICPFWVMPPPEQRPSDYGIPMDVEMAYVQDSFLTNDVLQEMMMLVEFYKGAPDLVKFQEAWSPEHTYLDKLKMSLASRTPKDQGMCHVLEQVCSVLKQGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TV65-1", "uniprot_id": "MPND_MOUSE", "id": "Q3TV65-1", "name": "MPN domain-containing protein", "aln": "MAAPESLSPG-ATAEEAPEEDEDDAEAEDPER-------GTGSGGRSGSLGGSGGGTAGPG--MALGGALTRRAVTLRVLLKDELLEPGEGVLSIYYLGRKFTGDLQLDGRIVWQETGQVFNSPSAWATHCKKLVNPAKKSGCGWASVKYKGQKLDKYKAAWLRRHQLHMPVATADESPTSEGEEEELLLEEEEEDVLAGVSSEDKGHRPPGKGSLE---PEATPPGKRMD-KVPVPIRYCMLGSRDSAR----------------------NPHTLVEVTSFAAINKFQPFNVAVSSNVLFLLDFHCHLTRSEVVGYLGGRWDINNQMLTVLRAFPCRSRLGDTDTAATVEEEIYQVLFLRGLSLVGWYHSHPHSPAVPSLQDIDAQMEYQLRLQGSSNGFQPCLALLCSPYYSGNPGPESKICPFWVMPPPEQRPSDYGIPMDVEMAYVQDSFLTNDVLQEMVMLAEFYKGAPDLVKFQEAWSPEHTYLDKLKMSLASRTPKDQGMCHVLEQVCSVLKQGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A061I1Y1-1", "uniprot_id": "A0A061I1Y1_CRIGR", "id": "A0A061I1Y1-1", "name": "MPN domain-containing protein", "aln": "MAAPEPLSPA-AAAEEAPEEDEDDAEAEDHER-------GAVSGGRSSSLSGIGGSSVGPG--LALGGALTRRAVTLRVLLKDELLEPGEGVLSIYYLGRKFIGDLQPDGRILWQETGQIFNSPSAWATHCKKLVNPAKKSGCGWASVKYKGQKLDKYKAAWLRRHQLHMPVAAADESPTSEGEEEELLLEEEEEDVLARVSAEEKGRRPPGKGSSE---PEVTALGKRVD-KVQVPVRYCMLGSRDSAR----------------------NPHTLVEVTSFAAINKFQPFNVAVSSNVLFLLDFHCHLTWSEVVGYLGGRWDINNQMLTVLRAFPCRSRLGDPDTAATVEEEIHQVLFLRGLSLVGWYHSHPHSPAVPSLQDIDAQMEYQLRLQGSSNGFQPCLALLCSPYYSGNPGPESKICPFWVMPPPEQRPSDYGIPMDVEMAYVQDSFLTNDILQEMVLLAEFYKGAPDLVKFQEAWSPEHTYLDKLKISLASRTPKDQGMCHMLEQVCSMLKQGS", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q8N594-1", "uniprot_id": "MPND_HUMAN", "id": "Q8N594-1", "name": "MPN domain-containing protein", "aln": "MAAPEPLSPAGGAGEEAPEEDEDEAEAEDPERPNAGAGGGRSGGGGSSVSGGGGGGGAGAGGCGGPGGALTRRAVTLRVLLKDALLEPGAGVLSIYYLGKKFLGDLQPDGRIMWQETGQTFNSPSAWATHCKKLVNPAKKSGCGWASVKYKGQKLDKYKATWLRLHQLHTPATAADESPASEGEEEELLMEEEEEDVLAGVSAEDKSRRPLGKSPSEPAHPEATTPGKRVDSKIRVPVRYCMLGSRDLAR----------------------NPHTLVEVTSFAAINKFQPFNVAVSSNVLFLLDFHSHLTRSEVVGYLGGRWDVNSQMLTVLRAFPCRSRLGDAETAAAIEEEIYQSLFLRGLSLVGWYHSHPHSPALPSLQDIDAQMDYQLRLQGSSNGFQPCLALLCSPYYSGNPGPESKISPFWVMPPPE------------------------------MLLVEFYKGSPDLVRLQEPWSQEHTYLDKLKISLASRTPKDQSLCHVLEQVCGVLKQGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08CH3-1", "uniprot_id": "MPND_DANRE", "id": "Q08CH3-1", "name": "MPN domain-containing protein", "aln": "MGSEPPSSPQ-VVEEGADEEDEELSGAEDADL--------RSSSGR--------------------GSLLTRRGITLRVLLKDGLVEPGDGVLSIHYLGKKFVGDLLNDGKIRWVETGQIFNSPSAWATHCKRLVNPAKKSGCGWASVRYRGQKLVQYKTTWLHKYQP-----SADMSLISEGEDDEMGDDDEEEGKTT-IPVEDKNK----KSKPE---LHEIGLTQRRD-RERIPVRYCTLGTRDAAR----------------------DPHTLVELSAFSAINRFQPFNVAVSSNVLLLMDFHCHLTSSEVVGYLGGRWDTNTQLLTVLRAFPCRTRLADKDAAPAVEEEICQNLFMRGLSLVGWYHSHPRGPALPSLQDIDSQMDHQLRLQGSSNGFQPCLGIICGPYYHGNQGVASTITPFWVVPPPEQRPNDHGIPVAVEVTYVQDNFLTTDVLNEMMLLVEFYRSAPDLVQFSQMWSPNTSILDKIKASLSGHAPKDQAYAQILEHVYNQLRNTQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: . *. . * * ****: : :** : ..* *. ****.:******** *:*** *****:***:** *** **:* * *.** ************:***************:*:**** :**::**: :* :** * ****::*: ::***. : :. * *.: *. * . :* * : :*:*** **:** ** :******:::*:***:*************:*:***.*** ************ *.*:**********:**.* ::*.::**** * **:*************:.** *******:**::*******.*******.::*.*** ** * *.* ****:**** ::*.***:.:****::.: ** : : ***:* **:.::****. .::**:* . *:: .", "identical_positions": 256, "similar_positions": 103, "identity": "48.95%" }, { "cls_id": "homologset.oma.821425", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CCG1-1", "uniprot_id": "ZC21C_MOUSE", "id": "Q8CCG1-1", "name": "Zinc finger C2HC domain-containing protein 1C", "aln": "MAGLQ-LAPHLPVGVMFPHNKTEAPGLHSAKHDPYEQSDSSQRPSMGHLRNSFQSKLWSNTEMEQEDEVSTRPKRNVCTKARRHSCPHSAGIRQQGSGNNAQGQGKGLFYLSSPTPRYPKANDQDFIPFRRKRVGVDRAYPLKPMVHRKSHSTSDAG-ADGDQNGYPRLPDSSEFSDNSFGL-RSWVNSSLLA----SVQAEKVVAELHRT--EWTQIQRLEAAGESLQKEIRRKEILLQEKLKKTEEGLRRMQKEKKQAIFQED--RELQR-MVLPRRRVRDGDHDTPHKPCLSPEFRS-EVFSRNRGEDQTCDQAQENPSPRQLSDYELQKLKRERLMASNSKIRDQDAGPSADAFFQPAEELG-STLQ----ESSRSGTPGSSGSSSSTEEPELAKCSHCGRSFLSLRLQRHSTVCGKMQGSKRKVFDSSRARAKGTELEQYLNWRGPATAKAETPPPPRKSTWRQKHESFIRTLRHARQVQQVIARGGNPSDLPSILPADNPDYVQCPHCSRHFAPKVAERHIPKCKTIKNRPPPPRRHDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYP4-1", "uniprot_id": "ZC21C_RAT", "id": "Q6AYP4-1", "name": "Zinc finger C2HC domain-containing protein 1C", "aln": "MAGLQ-LAPHLPVGVMFPHNKTEAHGLHSAKHDPYEQSDSPQRSSMGHLRTSFQQKLWSNTELEQEDVISTHPKRNICTKARRHSCPHSAGISQQGSGNNAQGQGKGLFYLSSPTPRYPKANDQDFIPFRKKRVGVDRAYPLKPMVHRKSHSTSETG-IDGDQNGYPRLPDSSEFSDSSFGL-RSWVNPSLLA----SPQAEKVMAQLHRT--EWTQIQRLEAAGESLQKEIRRKEILLREKLKKTEEGLRRIQREKKQAIFQED--RELQR-MVLPRRRVRDGDLDTTHNSCLSPELRS-EVFSRNRGEDQTCEQAQENSSPLQLSDYEIQRLKRERLMVSNNKIRDRDSGPSAGTFSQPAEDLG-DELQ----ASSLSGTPGSSGSSSSTEEQELGKCSHCGRSFLSLRLQRHSTVCGKMQGSKRKVFDSSRARAKGTELEQYLNWRGPATDKAE--PPPRKSTWRQKHESFIRTLRHARQVQQVIARGGNPSDLPSILPAENPDYVQCPHCSRHFAPKVAERHIPKCKTIKNRPPPPRRHDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3HFQ9-1", "uniprot_id": "G3HFQ9_CRIGR", "id": "G3HFQ9-1", "name": "", "aln": "MAGLQ-LAPHLPVGVMFPHSKTEAPGLHSAKHDPYEQRDSSQRSSVGHLRNNFQQKHWSNTELEQEEGVSTYPQRNICAKARRHSCPHSARISQRSPGSNPQGQGKALSSLSSPPPRYHKANDQDFIPFRKKRIGVDRAYPLKPMVHRKSLSTGEAGTGDGDQNVYPRLP---EFSDSNFGL-RSWVNSSILA----SVQAEEVMADLHRTRPEWTQIQRLEAAGETLQREIRRKETLLREKLKKTEEGLRRIQKEKKQAQQNED--RELPR-MMPAG-RVRE----SGCNAALSPEFSS-EMLSRNRREAQPCERAQEDSSPLQFSDYEIQRLKRERLMASNRKVR--DSATPAEEFSKPSEELG-STPQ----ASSLSGTPASSESSSSTEEPELGKCSYCGRTFLWLRLQRHSAVCGKMQGSRRKVFDSSRARAKGTELEQFLNWKGPATAKTE---PPRKSTWRQKHESFIRTLRHARQVQQVIAKGGNPSDLPPVLPAENPDYVQCLHCSRHFAPKVAERHIPKCKTIKNRPPPPRRYDS", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "E1BAI1-1", "uniprot_id": "E1BAI1_BOVIN", "id": "E1BAI1-1", "name": "", "aln": "MAGLQ-LVLPLPMGVMLPHNKRDSPELHSAKQDPYRKGDSSQRSSTGHPRNNFQQKLWSNQELMLDN-LYTHPKWNTCTKAQSCSYPHCAGMSQHDSRSNPQGQAKGLFYTSDPQCQYPKTNDQEFIPLTKKRVGVDRAYPLKPVFHRKSHSTGEAG-TDGDQNAFPRTPEPRKYSYSSFGS-RNWVNSSMVG-PVAATQEERVMANANRT--EWMQIQRLEAAGESLGEEIRRKETLLREKLKKTEEKLRRIQKGKEQAEENEK--RQLQR-MVLSRRRVKDN-SITTYKPIFSPALGSEEVFSRDTGEDETWGQSQENSSPFQFSNYRIQKLKRERLVASNNKIRDRVSRPLKEKFSQATEAPL-NALQRYTSNSSSSRAPDSSGSSCSTEEPELGECSHCGRKFLLLRLERHSSICRRMQGSKRKVFDSSRARAKGTELEQYLNWKGPASVKVT----------------------RALWICH-----------------------------------------------------------", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1S2Q5-1", "uniprot_id": "F1S2Q5_PIG", "id": "F1S2Q5-1", "name": "", "aln": "MAGLQ-LALTLPVGIMFPYNKREAPELHSVKQDPYEKGDSSQRSSMGHLRNNFQQELLSNKELTLDK-LYTHPKWNTSMKAWSCSYPHCAEISQQDSR-------KGLFYSSGPQSQYPKANIQEFIPFTKKRVGVDRAYPLKPVFHRKSRSTGEAG-TDGDQNVSLRSHQPRKLSYSSFGS-RNWVNSSVVG-SVAATQEERVVANPSRM--EWMQIQRLEAAGESLEEEIRRKETLLREKLKKTEEELRRIQKKKEQAEENEK--RELQRRMALPRRRVKGK-SNTSHKPIFSPEFKSAEVFSRDVGDDETWGRSQENSSPFQFSDHGIQKLKREGLMASNNQIRDRVSGPLKEKFSQASEMPP-SALQRSTCHSSLSRAPDSLGSSCSTEEPELGACSHCGRKFLLLRLERHSNVCSRMRGSKRKVFDSSRARAKGTELEQYLNWKGSASVKAEP---PRKSNWRQKHESFIRTLRQARQIQHVIAKGGNPSDLPPILPAENPDYIQCPHCSRHFAPKVAERHIPKCKTIKSRPPPPRKYDS", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q53FD0-1", "uniprot_id": "ZC21C_HUMAN", "id": "Q53FD0-1", "name": "Zinc finger C2HC domain-containing protein 1C", "aln": "MAGLQRLASHLPVGVMLPHNTTEAPGPHSAKQDSYEQGDSSQQSLKGHLRNNFQKQLLSNKELILDK-VYTHPKWNTQTKARSYSYPHCTGISQQDPESDSQGQGNGLFYSSGPQSWYPKANNQDFIPFTKKRVGVDRAFPLKPMVHRKSCSTGEAG-TDGDHNVYPRPPEPREFSSRNFGV-RNQGNFSVVGTVLAATQAEKAVANFDRT--EWVQIRRLEAAGESLEEEIRRKQILLRGKLKKTEEELRRIQTQKEQAKENEN--GELQK-IILPRSRVKGNKSNTMYKPIFSPEFEFEEEFSRDRREDETWGRSQQNSGPFQFSDYRIQRLKRERLVASNNKIRDPVSEPSVEKFSPPSETPV-GALQGSARNSSLSMAPDSSGSSGSIEEPQLGECSHCGRKFLSFRLERHSNICSRMRGSKRKVFDSSRARAKGTELEQYLNWKGPASAKAEP---P----------------QKSNWR-------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1NAH9-1", "uniprot_id": "F1NAH9_CHICK", "id": "F1NAH9-1", "name": "", "aln": "MAELQ--------VALFPYVDPVVAAAKLPVTDSYDSEVSVHQYPLEHLKNSCQREFLSDKEEGLKN--------PLARKSRSYSYSLSAESNKHSSQHGGSSSAGLQNKHLASQVKTLPSK-----SVAKRKEGVDRSCPLKPIFHHNTGSLPAVN--TGQLGSSPNMEEALNSKTSSKSKGRHLPGKPQLAAVLPPWTAEPKQSDSSLYRRDLAYILRLEADGQTLEKEIRKKEALLREKLRRTKEELRRIQREKELMEAEERRAR------AVERTRRQKAVWQPGEENIRFTIRMDDGDFSGVQSAEVTVPKTGTTLHP---QELAMGKLKKERLVASNNKIRDRIPVEDLASCSELALKHGPSSSALSDCGDRLPAEMLYMQAASPTEQGELGKCSFCGRKFLCARLKKHMSICSKSQGSKRKTFDSSKARARGTDLEEFQQWKSSERPQNKP---PRRNNWRQNHEAFIQTLRHARQVQQVLSKGGKVSDLPPLPPIENPDYTACPYCRRRFAPQVAETHIPKCKNIKNRPSLPPQRKR", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ** ::*: : *.* . * :: * :.. * : *: * .. *: * . .: ::.. . :: .. ::: ****: ****:.*::: * .. *: . . : . . . * . . :. . * :: : * **** *::* .***:*: **: **::*:* ***:* *: :* * : . : . :* . :: * .: : :**:* *:.** ::* . : . . . :: . *: :*. **.***.** **::* :* : :**:**.****:***:**:**:: :*:.. : :: ", "identical_positions": 89, "similar_positions": 115, "identity": "16.33%" }, { "cls_id": "homologset.oma.821453", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "C0HKD1-1", "uniprot_id": "31F12_MOUSE", "id": "C0HKD1-1", "name": "Spermatogenesis-associated protein 31F1B", "aln": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C0HKD3-1", "uniprot_id": "31F14_MOUSE", "id": "C0HKD3-1", "name": "Spermatogenesis-associated protein 31F1D", "aln": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C0HKD2-1", "uniprot_id": "31F13_MOUSE", "id": "C0HKD2-1", "name": "Spermatogenesis-associated protein 31F1C", "aln": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************", "identical_positions": 1308, "similar_positions": 0, "identity": "100.0%" }, { "cls_id": "homologset.oma.821837", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZSU4-1", "uniprot_id": "D3ZSU4_RAT", "id": "D3ZSU4-1", "name": "", "aln": "--MWKRRGRGESAARTAAVASRLRPPGSLNTMSAPPASNGVFVVIPPSNASGLRPPPAILPTSMCQPPGIMQFEESPLGAQAPRATQP-PDLRPMETFLTGEPKALGTVQILIGLIHLGFGSVLLMVRRGHLGMLFIEGGVPFWGGACFIISGSLSVAAERNHTSCLVRSSLGTNILSAMAAFAGTAILLMDFGVTNWDVGRGYLAVLTIFTILEFFIAVIATHFGCQATRAQTNASVIFLPNAFGTDFSIPSPAVSPPPAYDNVAYMPKESSE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UPL6-1", "uniprot_id": "M4A15_MOUSE", "id": "Q3UPL6-1", "name": "Membrane-spanning 4-domains subfamily A member 15", "aln": "--MWERRGRGESAAGTAAVASR--------------------------NASGLRPPPAILPTSMCQPPGIMQFEESQLGAQAPRATQP-PDLRPMETFLTGEPKALGTVQILIGLIHLGFGSVLLMVRRGHLGMLFIEGGVPFWGGACFIISGSLSVAAERNHTSCLLKSSLGTNILSAMAAFAGTAILLMDFGVTNWDVGRGYLAVLTIFTILEFFIAVIATHFGCQATRAQTNASVIFLPNAFGTDFNIPSPAVSPPPAYDNVAYMPKESSE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N5U1-1", "uniprot_id": "M4A15_HUMAN", "id": "Q8N5U1-1", "name": "Membrane-spanning 4-domains subfamily A member 15", "aln": "------MSAAPASNGVFVVIPP-------------------------NNASGLCPPPAILPTSMCQPPGIMQFEEPPLGAQTPRATQP-PDLRPVETFLTGEPKVLGTVQILIGLIHLGFGSVLLMVRRGHVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGVTNRDVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAFSADFNIPSPAASAPPAYDNVAYAQGVV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0ZD10-1", "uniprot_id": "A0A8V0ZD10_CHICK", "id": "A0A8V0ZD10-1", "name": "", "aln": "MLIVPSTTRVDLAVVQAELPQP-------------------------PSYSEVMATTVTESGGVRIITEVIPATDPRAAQLVSGSVQPTVSSFQISGFRRAQPKVLGTIHIVTGIIHLCFGVILTCAENNSALSLPVASGVFFWLGVLLLVSGSLLVESEKRENILLVKVCCVANAAVILSSLV--AMLIHTVAITHNIPGCRSSASMPLLVRQEWCFSAETKAL----SNGFDSILVLFGLLEFCTAVAALAFGCTAIKQYSYTRMVL-----", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . * : .... . .: . :: :. . .. :.** . :. * .:**.***::*: *:*** ** :* .... : : .** ** *. :::**** * :*:... *:: . :* ::::. *:*: ..:*: . * :.::. *: :. : : .. . *:* * : . : . :. *. . ", "identical_positions": 39, "similar_positions": 86, "identity": "14.23%" }, { "cls_id": "homologset.oma.821838", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q96JQ5-1", "uniprot_id": "M4A4A_HUMAN", "id": "Q96JQ5-1", "name": "Membrane-spanning 4-domains subfamily A member 4A", "aln": "MHQ--TYSRHCRPEESTFSAAMTTMQGMEQAMPGAGPGVPQLGNMAVIHSHLWKGLQEKFLKGEPKVLGVVQILTALMSLSMG-ITMMCMASNTYGSNPIS-VYIGYTIWGSVMFIISGSLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYCNYYGNSNNCHGTMSILMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHMAETASPTPLN-----------EV-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RIC5-1", "uniprot_id": "F1RIC5_PIG", "id": "F1RIC5-1", "name": "", "aln": "MKKPCTFSEVCC-KASTFSAAMITTQEMEQTTPGADPDVHQPRQLSSLRSHLWKEMLEKFLKGEPKILGVVQVLIALMNSSLGTVVMSVTLSHKYLEYSFYLACAGYIISASVMFIISGSLSIAAGTKGTKGLVQGSLGLNITSSILAAIGIILLSLSFLVSSFDYT-CRSNPDLENCSMILSILMGMNGMVLILTLLEFCIALSLSAFGCKVTCCKSGGVVFILPSNVHMAETASPAPLAGGLMPPTDQQKNVPENLSLQ", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A087WRT7-1", "uniprot_id": "A0A087WRT7_MOUSE", "id": "A0A087WRT7-1", "name": "", "aln": "---------------------MLVIQGTEQSALEAGYGAQQNGQPLYVNSHSWKRMTEKFLKGEPKILGIVQIVIAIMNLSIG--IMMIIATVSTGEIPPSSVYIGYPIWGSLMFIISGSFSIVAGRRTTKGLVRSSLGLNITSSVFAFSGIVISSLSPGIYSFHVYYCTYRGSSEGCHMTLSILMGLDIVVVVLSVLEFCIGVSLSAFGCRVMCCNPGGVMIIMPSNPTKAETANPVTLQSGLMPPEHQERNVPENMH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R3W2-1", "uniprot_id": "M0R3W2_RAT", "id": "M0R3W2-1", "name": "", "aln": "---------------------MITIQGTGQTALEAGYGAQQNGQPLYVDSHSWKRMTEKFLKGEPKILGIVQIVIAIMNLSIG--LMMIGATVSSGEILPISVYIGYPIWGSIMFIISGSFSIVAGRRTTKGLVRSSLGLNITSSVFAFAGMIINSLSPSIYSFHVYFCTYRSTSEGCRMTLSILMGLDIVVVILSVLEFCIGISLSAYGCRVMCCNPGGVVIIMPSKPPMPETAYPVSLQSGLGPPEHQQKNVPGKSH--", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * *: *. .. * : : ** ** : *********:**:**:: *:*. *:* * : . . . ** * .*:*******:**.** : *****:.***:*****::* *::: ::* . **. * :.* :*****:: :*::*::*****.:****:**:* **..***::*:**: .*** *..* :* ", "identical_positions": 95, "similar_positions": 60, "identity": "36.4%" }, { "cls_id": "homologset.oma.821839", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZDZ2-1", "uniprot_id": "D3ZDZ2_RAT", "id": "D3ZDZ2-1", "name": "", "aln": "MNHPTAQGAVTLSENKSSTAE-WEQEQERLIWQPGTVSMNTVTSQGPVANSVYVVAPHNSYPVVPGTMPQVPLYPSNQPQVHVIPGNLPGLVPAMTEPPAQRVLKKGQVLGAIQILIGLVHIGLGSIMITNLFSLYTPVSLYGGFPFWGGIWFIISGSLSVAAETQPNSPCLLNGSVGLNIFSAICSAVGIILFITDISISGGYVYPDYYPYHD-YGVSTGVAISCVLLIFCLLELSIASVSSHFGCQVACCRYNNVDVVIPNVYATNTVVFPEPPNPIPSYSDAIRDSR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N10-3", "uniprot_id": "M4A8_MOUSE", "id": "Q99N10-3", "name": "Membrane-spanning 4-domains subfamily A member 8", "aln": "MNRPTAQGAVNLSGSKFSTAKSWEPEQERLTWQPGTVSMNTVTSPGPMANSVYVVAPPNSYPVVPGTVPQMPIYPSNQPQVHVISGHLPGLVPAMTEPPAQRVLKKGQVLGAIQILIGLVHIGLGSIMITNLFSHYTPVSLYGGFPFWGGIWFIISGSLSVAAETQPNSPCLLNGSVGLNIFSAICSAVGIMLFITDISISSGYIYPSYYPYQENLGVRTGVAISSVLLIFCLLELSIASVSSHFGCQVACCHYNNPGVVIPNVYAANPVVIPEPPNPIPSYSEVVQDSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BY19-1", "uniprot_id": "M4A8_HUMAN", "id": "Q9BY19-1", "name": "Membrane-spanning 4-domains subfamily A member 8", "aln": "--------------------------------------MNSMTSAVPVANSVLVVAPHNGYPVTPGIMSHVPLYPNSQPQVHLVPGNPPSLVSNVNGQPVQKALKEGKTLGAIQIIIGLAHIGLGSIMATVLVGEYLSISFYGGFPFWGGLWFIISGSLSVAAENQPYSYCLLSGSLGLNIVSAICSAVGVILFITDLSIPHPYAYPDYYPYAW--GVNPGMAISGVLLVFCLLEFGIACASSHFGCQLVCCQSSNVSVIYPNIYAANPVITPEPVTSPPSYSSEIQANK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "K7GKI5-1", "uniprot_id": "K7GKI5_PIG", "id": "K7GKI5-1", "name": "", "aln": "--------------------------------------MNPMNTAGPAPNSVFVVTSPDGYTVLPSGMTQV--YPSYQPQAFVG------------QPPAQGTLKEGKALGAVQILIGLFYLGLASIMGTVLARGYLAISFNGGFPFWAGIWFIVSGSLSVTAEKQPRSSCLLNSSLGFNILSAIYSLVGICLFTAELVIAPSFLWTDHHSPPF-WNVITGIAISSVFLIFCLLEFCIACACAHFGCQLVCYKPKTVGMVIPNIYVANPVVNPEPENTPPDYSN-IQGDK", "tax_id": 9823, "tax_name": "Pig" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.:.: * .*** **:. :.*.* *. :.:: **. ***..: *.* .**:*:.***:**:*** ::**.*** * * * .:*: ******.*:***:******:**.** * ***..*:*:**.*** * **: ** ::: *. : :..::. .* .*:*** *:*:*****: **...:*****:.* : .. .:: **:*.:*.*: *** .. *.**. :: .:", "identical_positions": 106, "similar_positions": 85, "identity": "36.55%" }, { "cls_id": "homologset.oma.821841", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AI50-1", "uniprot_id": "A0A8I6AI50_RAT", "id": "A0A8I6AI50-1", "name": "", "aln": "MHSTVSAALETMQGLAQSTTAVVPGGTQPSEPSVIKSQRWNENKEKFLKGEPKVLGVVQVMIALINLSLGVIVMKTMGFGSLISVALQAPIWGPVMFIVSGSLSIAAGVKTTKSLVISSLSLNTISSVLAAAASIMGVVSVVLSTYSFLYGSDPITRALDVLMLILNILEFCIAVSISAFGCKASCCNSSEVLVVLPSNPPVTVMAPSIPLQPLLPPECQGKNVPENVY---PGEIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N05-1", "uniprot_id": "M4A4D_MOUSE", "id": "Q99N05-1", "name": "Membrane-spanning 4-domains subfamily A member 4D", "aln": "-----------MQGLAQTTMAVVPGGAPPSENSVIKSQMWNKNKEKFLKGEPKVLGAIQVMIAFINFSLGIIIILNRVSERFMSVLLLAPFWGSIMFIFSGSLSIAAGVKPTKAMIISSLSVNTISSVLAVAASIIGVISVISGVFR-QFRSQPAIASLDVLMTILNMLEFCIAVSVSAFGCKASCCNSSEVLVVLPSNSAVTVTAPPMILQPLPPSECQGKNVPENLYRNQPGEIV", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******:* ******: *** ****** **:**************.:*****:**:***:*:: . ::** * **:**.:***.***********.**:::*****:********.****:**:**: ..: : *:* :***** ***:********:**********************..*** **.: **** *.**********:* *****", "identical_positions": 159, "similar_positions": 40, "identity": "67.09%" }, { "cls_id": "homologset.oma.821842", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1LVJ1-1", "uniprot_id": "F1LVJ1_RAT", "id": "F1LVJ1-1", "name": "", "aln": "MGDIRTSFQTTYPGMRGTIPNPYPPTSSMGLHPQQPLGFSNVGNQVRTGQVSFITSPGIFPNNQLGRENVPRVNPAPGAATS--NVKDAAVALGGVQITIGLMHIGFGVVLGLLSTSYSMTWAFYSTAFIGGYPFWGGVFFIVSGSLSVSAFKKFSDCLVKSTLIINIFSIISAFVGVVLFLCDLNNNGHYYQDYWMVLSGRGIAGVLAIFSLLEFSIAWATAYFAYQTILHG-NRSVLVAPTVYAANHLMQESSPASPIYDNVPDYAVRQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A087WSB9-1", "uniprot_id": "A0A087WSB9_MOUSE", "id": "A0A087WSB9-1", "name": "", "aln": "----MTSSQTTYPGTRG-IPNPCPPTRSMAPHPPQPLNFLNVRNQVQTGQVSFITSPGIFPNTQLGRENVPTVNPALGAAIS--NVKDAAIALGGVQITIGLMHIGFGVVLGLLSTSYNMTWAFSSVAFIGGYPFWGGVFFIASGSLSISAFKEFSHCLMKSTLIINISSTIFAFVGVILFLCDLNINGYYYQDYWMVLSGRGIAGVLAIFSLLEFSIAGAMAYFAHQGILRC-NRSVPVAPAVYVANPLMRESPSAPPIYDNIPDYATTQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A9J7K4P4-1", "uniprot_id": "A0A9J7K4P4_CRIGR", "id": "A0A9J7K4P4-1", "name": "", "aln": "---MTSSQTTTYPGMHVTIPNPYPPTSSMAHHPQQPLGILNVGNQVQTGQLPFITSPGIFTTNRFGPENVPTVHPAPVTTTTKANFKDEAIALGAVHIIIGLMHIGFGVVLGLLNSYYYVSWAFYSIAFIGGYPFWGGVSFIASGSLSISAFKKFTPCLVKSTLTMNIISAVFAFVGVILFVVDLNINGYHYQNYWMVLSGRGIAGMLAIFSVLEFGVACAMTHFANQTRMHGSNRSVPTAPSMYVVDSLMQESFPDSRRYDNIPAYAPRQ", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* ***** : **** *** **. ** ***.: ** ***:***:.********...::* **** *:** :: : *.** *:***.*:* ***************.: * ::*** * ************ **.*****:****:*: **:**** :** * : *****:**: *** **::**:************:*****:***.:* * ::** * :: **** .**::*..: **:** . . ***:* ** *", "identical_positions": 163, "similar_positions": 55, "identity": "60.15%" }, { "cls_id": "homologset.oma.821853", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AI50-1", "uniprot_id": "A0A8I6AI50_RAT", "id": "A0A8I6AI50-1", "name": "", "aln": "--MHSTVSAALETMQGLAQSTTAVVPGGTQPSEPSVIKSQRWNENKEKFLKGEPKVLGVVQVMIALINLSLGVIVMKTMGFGSLISVALQAPIWGPVMFIVSGSLSIAAG----VKTTKSLVISSLSLNTISSVLAAAASIMGVVSVVLSTYSFLYGSDPITRALDVLMLILNILEFCIAVSISAFGCKASCCNSSEVLVVLP--SNPPVTVMAPSIPLQPLLPPECQGKNVPENVYPGEIV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A5WUV1-1", "uniprot_id": "A5WUV1_DANRE", "id": "A5WUV1-1", "name": "", "aln": "MSTVRTMNPSTIVIQLQPPTQTATVTSSSVPVRIQRVAGVSPRQGNQAFLKGQPKALGTVQIMIGVVTLLLEIVCTS---YGYYLFLFTGASYWGSLIYIIAGSLSIAAENKINSPTGLCLVRASLGMNIFSAIAAGISIIVLPIGLAFGPF-YSYSYTSLLSGISCVLLVFAILEFCISICLFAFACKVTCCCKPKIPVSSNPLIQHPPAEMPPQYIQCPQEVPEPCFQHPPAESPPAYTEGE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:..: .:* . : **.*...: * . . : . .:.:: ****:**.**.**:**.::.* * :: . :* : : *. **.:::*::******* * .** :**.:* :*:: *. : *: :.:.:..: : *. .: .:. ::*:: ******::.: **.**.:** ..:: * : * : *.*. * ** :: * : *. ", "identical_positions": 64, "similar_positions": 91, "identity": "26.23%" }, { "cls_id": "homologset.oma.821855", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AI50-1", "uniprot_id": "A0A8I6AI50_RAT", "id": "A0A8I6AI50-1", "name": "", "aln": "MHSTVSAALETMQGLAQSTTAVVPGGTQPSEPSVIKSQRWNENKEKFLKGEPKVLGVVQVMIALINLSLGVIVMKTMGFGSLISVALQAPIWGPVMFIVSGSLSIAAGVKTTKS----LVISSLSLNTISSVLAAAASIMGVVSVVLS------TYSFLYGSDPITRALDVLMLILNILEFCIAVSISAFGCKASCCNSSEVLVVLPSNPPVTVMAPSIPLQPLLPPECQGK---NVPENVYPGEIV---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1QTD0-1", "uniprot_id": "F1QTD0_DANRE", "id": "F1QTD0-1", "name": "", "aln": "-----------MTSSSVPVHMQHAAGVSP-----------HQGIQLFLQGQPKVLGAVQIMIGAWTFLLGIVTFAYAAGG--------VSYGASVIYIIAGSLSIAAEIKINSPDALCLVRASLGMNIFSAIAAGSSIIVLSQAMAFARIVTRCRDAHCYNDVTIFIGISGVLLVFAILEFCISISLSVFACKVACCCKPKIPVEN--NILIQHTPAEIPQQYIQCPQEVPEPYFQHPPAGFPPAYTEGK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : .. ..*..* ::. : **:*:*****.**:**. .: **::.: . * .. ..*::*::******* :* ... ** :**.:* :*:: *.:: *: ::.:: :. *.. .* .:. ::*:: ******::*:*.*.**.:** ..:: * * : ...** * : *: : : * :* . ", "identical_positions": 60, "similar_positions": 84, "identity": "24.0%" }, { "cls_id": "homologset.oma.821915", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JUH0-1", "uniprot_id": "A0A0G2JUH0_RAT", "id": "A0A0G2JUH0-1", "name": "Olfactory receptor", "aln": "MADLFNVTEFIFLGLSPNKEVQRVCFVLFLLLYMAIVLGNLLMVVTVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLILDLLAEKKSISVWGCMTQLFFLHYFGGIEIFLLTVMAYDRYVAICKPLHYTSIMNRKVCIVLVGTAWTGGFVHSFAQIVLIFPLPFCGPNTIDHYFCDVLPLLKLACSDTFLIGLLIVANAGTLSVISFVVLLASYVVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRPSDTLPVDKIIAVFYTVITPLLNPLIYSLRS---------------------------------------------------------------------------------------------AEVKKAMK----------DLW-----------FRTMKADEK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEZ3-1", "uniprot_id": "Q8VEZ3_MOUSE", "id": "Q8VEZ3-1", "name": "Olfactory receptor", "aln": "MADIHNVTEFLFLGLSSNKEVEIVCFVIFLLLYMAIVLGNLLMVVTVVASRSLGSPMYFFLGYLSFVEICYSSTTAPKLILDLLAEKKSISVWGCMTQLFFMHFFGGAEIFLLTVMAYDRYVAICKPLHYTSIMNRNVCAVLVGTAWIGGFVHSFAQILLIFPLPFCGPNIIDHYFCDLLPLLKLACSDTFLIGLLIVANAGTLSVISFVVLLASYVVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYLRPSDTLPVDKMIAVFYTVITPLLNPLIYSLRN---------------------------------------------------------------------------------------------AKVKKTMK----------SLW-----------FRTMKVDEK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AAA9SY50-1", "uniprot_id": "A0AAA9SY50_BOVIN", "id": "A0AAA9SY50-1", "name": "", "aln": "MGAKNNLTEFVLLGLFRSQEMQRACFLVFSLFHVLTVLGNLLVIVTINASKTLHAPMYFFLCHLSFADMCYPSASTPKMIADTLVERKTISFKGCMTQLFSAHFFGGTEIFLLTAMAYDRYVAICRPLHYETIMGRRKCGLLAGASWVAGFLHSILQTLLTVQLPFCGPNEIDSFFCDVHPLLKLACADTYVVGLIVVANSGMISLVSFIILIISYVVILLNLRSRSSESQRKALSTCGSHIIAVLLVLVPPMFMYIRPSTTLAADKLVILFNIVMPPLLNPLIYTLRNSEFCQENALVIANTLFQQYTWTSSDDQHQNQIDYILCSQRWRSSIQSTKTGPGADYGSDHELLIAKFRLKLKKIGKTNRPFRYDLNQIPYDYTVEVRNRFKGLDLIDRVPDELWTEVCDIVQETGIKTIPMEKKCKKARWLSGEALQIAVKRREAKSKGEKERYKHLNVEFQRIARKAKKAFLSDQCKEIEENNRMGKTRDLFKKIRDTKGTFHAKMGSIKDRNGMDLTEAEDIKKRWQEYTEELYKKDLHDPDNHDGVITHLEPDILECEVKWALESITNKASGGDGIPVELFQILKDDAVKVLHSICQKIWKPQQWPQDWKRSPIEIPASWWLHHG", "tax_id": 9913, "tax_name": "Bovine" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. *:***::*** .:*:: .**::* *::: ******::**: .*:.* :****** ***.::**.*:::**:* * *.*:*:**. ******* *:*** ******.**********:**** :**.*. * :*.*::* .**:**: * :* . ******* ** :***: *******:**:::**::***:* :*::**::*: ******::**::*:*.:**********: .*:*.: * :*:* *** **..**:: :* *:.********:**. .:*:: :* .** ::*: ::* ", "identical_positions": 169, "similar_positions": 97, "identity": "26.95%" }, { "cls_id": "homologset.oma.821934", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQ42-1", "uniprot_id": "D3ZQ42_RAT", "id": "D3ZQ42-1", "name": "Olfactory receptor", "aln": "MGNFNTSSQESFILVGFSDWPQLQVFLFVIILIFYSLTIFGNTTIIILARLDLRLHKPMYFFLSHLSFLDLCYTTSTVPQLLINLYGLDRTISYGGCVAQLFIFLALASTECLILVAMAFDRYAAVCHPLHYTSIMHPILCRALAISSWVGGLVNSLIQTGLVMAMRLCGHQINHFFCEMPIFLKLACEDTGGTEVKMFVARTIVLVCPAVLILGSYVHIAKAVLKVKSMAGRRKAFGTCGSHLMVVSLFYGSGIYTYLQPVHKYSESKGKFVALFYTIVTPMFNPLIYTLRNKEVKGALWKMLGRGTDSG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VFA9-1", "uniprot_id": "Q8VFA9_MOUSE", "id": "Q8VFA9-1", "name": "Olfactory receptor", "aln": "MGNFNTSTQESFILVGFSDWPQLQAFLFVIILIFYSLTIFGNTTIIVLARLDLRLHKPMYFFLSHLSFLDLCYTTSTVPQLLINLRGLDRTISYGGCVAQLFIFLALASTECLILVAMAFDRYAAVCHPLHYTSIMNPILCRALAISSWVGGLVNSLIQTGLVMAMRLCGHQINHFFCEMPIFLKLACEDTEGTEAKMFVARTIVLVCPAVLILGSYVHIAKAVLKVKSMAGRRKAFGTCGSHLMVVSLFYGSGIYTYLQPVHRYSESKGKFVALFYTIVTPMFNPLIYTLRNKDVKGALWKLLGRGTDSG", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******:****************.*********************:************************************** **************************************************:****************************************************** ***.*******************************************************************:******************************:*******:********", "identical_positions": 301, "similar_positions": 8, "identity": "96.78%" }, { "cls_id": "homologset.oma.821935", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VGW9-1", "uniprot_id": "Q8VGW9_MOUSE", "id": "Q8VGW9-1", "name": "Olfactory receptor", "aln": "MGSFNTSFRQGFFLVGFSDFPQLELLLSVLISIFYSLTLFGNSTIIILSQLDARLQMPMYFFLCHLSFLDLCYTTSIVPQLLINLQGYDRTISYGGCVAQLFLFLALATTESVLLVVMAFDRYVAVCRPLHYTTIMHPVLCLSLAIVSWVGGFMNSLIQTSLMMAVPLCGHRLNHFFCEIPSLLKLACEDTEGTGAKMFVVRVVFLIFPITLILSSYANIAQAVLKTKSMAGCKKALGTCGSHLVVVSMFYGAAMYTYLQPKGTYSESKGKFVALFYIIVTPMLNPLIYTLRNKDVKGALWKVLGRATDLG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8C2LQQ3-1", "uniprot_id": "A0A8C2LQQ3_CRIGR", "id": "A0A8C2LQQ3-1", "name": "Olfactory receptor", "aln": "MGSFNTSFRHSFVLVGFSDFPQLELILSVFISIFYSLTLFGNSTIIILSQLDARLQTPMYFFLCHLSFLDLCYTTSIVPQLLINLQGYDRTISYGGCVAQLFLFLALASTESVLLVVMAFDRYAAVCRPLHYTAIMHPLLCLSLAITSWVGGFMNSLIQTGLMMAMPLCGHQLNHFFCEMPILLKLACEDTEGTEAKMFVARVVILIFPVTLILGSYANIAHAVLKTKSMAGCKKALGTCGSHLVVVSMFYGAAIYTYLQPKGSYSESKGKFVALFYTIITPMLNPLIYTLRNKDVKGALWKVLRRGTDSG", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********:.*.************:***:************************** ***************************************************:**************.*********:****:*******.*************.****:*****:*******:* ************ *****.***:****:****.******:********************************:********:************* *:************************ *.** *", "identical_positions": 282, "similar_positions": 23, "identity": "90.68%" }, { "cls_id": "homologset.oma.821950", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZPU8-1", "uniprot_id": "A0A8I5ZPU8_RAT", "id": "A0A8I5ZPU8-1", "name": "Olfactory receptor", "aln": "MQNQSFVTEFILLGLTENPKVEKILFVWFFLVYLATIGGNIIIVVTIICNPTLFGSPMYFFLSFLSFLDACVSTVITPKMIIDFFYEKKTISFECCMIQLFAVHFFTGAEVIVLSAMAYDRYVAICKPLHYSSIMTRRLCVILVGVAWAGGFLHSIIQIIFILQLPFCGPNVIDHFVCDLFPLLKLACTNTHIFVILVFANSGSICIIIFSILLVSYGVILFSLRAHSSEGRRKALSTCGSHITVVLLFFVPCILIYARNNSEFSFEKNVFIFDDVLTPMLNPLAYTFRNKEIKNAIKKMWKRLFNISYKQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A3KGY4-1", "uniprot_id": "A3KGY4_MOUSE", "id": "A3KGY4-1", "name": "Olfactory receptor", "aln": "MQNQSIVTEFILLGLSQNPKVEKILSVLFFLVYLATIGGNIIIVVTIVFSPALSGSPMYFFLSFLSFLDACVSSVITPKMIVDFFYERKTISFECCMIQLFAVHFFTGVEVIVLSAMAYDRYVAICKPLHYSSIMTQRLCGILVGIAWAGGFLHSIIQIIFTLQLPFCGPNVIDHFVCDLFPLLKLACTNTHIFVILVFANSGSICIIIFSILLVSYGVILFSLRNHSSEGRRKALSTCGSHITVVLLFFVPCILIYARNNSEFSFEKNVFIFDDVLTPMLNPLAYTFRNKEMKNAIKKMWRRLFNISDKH", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:*********::******** * *******************: .*:* *******************:*******:*****:********************.***************************:*** ****:*************** *************************************************************** ******************************************************************:********:****** *:", "identical_positions": 288, "similar_positions": 15, "identity": "92.6%" }, { "cls_id": "homologset.oma.821951", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A892-1", "uniprot_id": "A0A8I6A892_RAT", "id": "A0A8I6A892-1", "name": "Olfactory receptor", "aln": "MQNQSFVNEFILLGLSQNPKVEKILFVVFLLVYIATIGGNIMIVVTIIYSPALLGSPMYFFLIFLSLLDACTSSTVTPKMIVDFFYERKTISFECCITQLFTSHFFAGVEVIILTSMAYDRYVAICKPLHYSSIMTRRLCGTLVGVAWTGGFLHSITQVIFTLQLPFCGPNFIDHFICDLFPLLQLACTDTHIFVILVFANSGSFCIIIFSLLIISYGVILFSLRGHSSEGRRKALSTCGSHITVMILFFVPCMLIYARPSSAFSFEKNTLIFASVLTPLLNPMVYTFRNKEMKNAIRKMSRKLIVVSNTF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TR02-1", "uniprot_id": "Q7TR02_MOUSE", "id": "Q7TR02-1", "name": "Olfactory receptor", "aln": "MQNQSFVTEFILLGLSQNPKVEKILFVVFLLVYIATIGGNMIIVVTIIYSPALLSSPMYFFLIFLSFLDACTSSTVTPKMIVDFFYERKTISFECCITQLFTSHFFAGVEVIILTSMAYDRYVAICKPLHYSSIMTRRLCGTLVMVAWTGGFLHSITQVIFTLQLPFCGPNFIDHFICDLFPLLQLACTDTHIFVILVFANSGSFCIIIFSLLIVSYGVILFSLRGHSSEGRRKALSTCGSHITVMILFFVPCMLIYARPSSAFSFEKNTLIFASVLTPLFNPMVYTFRNKEMKNAIRKMCRKLLVDSDNF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3HPC0-1", "uniprot_id": "G3HPC0_CRIGR", "id": "G3HPC0-1", "name": "Olfactory receptor", "aln": "MQNQSFVTEFILLGLSQNPKVEKVLFVLFLLVYIATIGGNMIIVVTIICSPALLGSPMYFFLAFLSLLDACTSTTVTPKMIVDFFYERKTISFECCMTQLFTSHFFAGVEVIVLTAMAYDRYVAICKPLHYSSIMTRRLCGTLIGVAWTGGFLHSITQVIFTLQLPFCGPNFIDHFICDLFPLLQLACTETHIFVILVFANSGSFCIIIFSLLIVSYGVILFSLRGHSSEGRSKALSTCGSHITVVILFFVPCILIYARPSSAFSFEKNTLIFASVLTPLLNPMVYTFRNKEMKNAFKKMCNRLIVASDKY", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******.***************:***:************::****** *****.******* ***:******:**********************:***************:**:***************************: ********************************************:************************:***************** ************:*******:**************************:***************::**..:*:* *:.:", "identical_positions": 280, "similar_positions": 26, "identity": "90.03%" }, { "cls_id": "homologset.oma.821954", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TR05-1", "uniprot_id": "Q7TR05_MOUSE", "id": "Q7TR05-1", "name": "Olfactory receptor", "aln": "MQNQSSVTEFIILGLSQNPKIEKILFVVFLLVYMATVGGNMIIVVTIIYSPALLSSPMYFFLAFLSFLDACVSSTVTPKMVVDFLHEKKTISFGCCMTQLFSVHFFSGAEMIVLAAMAYDRYVAICKPLHYSSILTRRLCSILVAISWAGGFLHAIVQVIFTLQLPLCGPNVIDHYMCDLFPLLKLACTDTHIFVLLVFANSGAICIIIFSLLLVSYGVILFSLRAHSSEGRRKALSTCGAHVTVVVLFLVPCILIYARDTSAFSYEKDTLIFVNVLTPLLNPMVYTFRNKEMINAIRKMWKRLIVIFVRY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3HPC1-1", "uniprot_id": "G3HPC1_CRIGR", "id": "G3HPC1-1", "name": "Olfactory receptor", "aln": "MQNQSFVTEFIILGLSQNPKVEKILFVVFLLVYLATIGGNMIIVVTIIYSPALLGSPMYFFLAFLSFLDACVSSTVTPKMIIDFLCEKKIISFGCCMTQLFSVHFFSGAEMIVLAAMAYDRYVAICKPLHYSSILTRKLCSILVAISWAGGFLHSIIQIIFTLQLPLCGPNVIDHYMCDLFPLLKLACTDTHIFVLLVFANSGAICIIIFTLLIVSYGVILFSLRAHSSEGRRKALSTCGAHVTVVVLFLVPCILIYARDTSAFSFEKNTLIFVNVLTPLLNPMVYTFRNKEMINAIKKMWKRLKVIFVRF", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** **************:************:**:*****************.*************************::*** *** ***********************************************:****************:*:*:***************************************************:**:***************************************************:**:****************************:****** *****:", "identical_positions": 291, "similar_positions": 16, "identity": "93.57%" }, { "cls_id": "homologset.oma.821956", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZGE3-1", "uniprot_id": "D3ZGE3_RAT", "id": "D3ZGE3-1", "name": "Olfactory receptor", "aln": "MQNQSFVTEFILLGLSQNPKVEKILFIIFLLLYLATIGGNMTIVVTIVWNPALLGSPMYFFLAFLSLLDACVSSIVTPKMIIDLFYKRKSISFECCMTQVFSVHFFSAVEVIILAAMAYDRYVAICKPLHYSSIMNRRLCGILVGVAWAGGFLHSIIQIIFTLQLPFCGPNFIDHFICDLFPLLKLACTDTHIFVILVFANSGSICIIIFSFLLVSYGVILFSLRTHSSEGRRKALFTCGSHITVVVLFFVPCILIYARPTSPFSLEKNVFIFADVLTPLLNPMVYTFRNKEMKNAIRKMWRKLLVAPNTY-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A3KGY3-1", "uniprot_id": "A3KGY3_MOUSE", "id": "A3KGY3-1", "name": "Olfactory receptor", "aln": "MQNQTIVTEFVLLGLSQNPKVEKLLFVIFLLLYLATIGGNMTIVVTIASSPVLLGSPMYFFLAFLSLLDACVSSIVTPTMIIDLFYKRKTISFECCMTQVFSVHFFSAVEVIILAAMAYDRYVAICKPLHYSSIMNRRLCGILVGIAFAGGFLHSIIQIIFTLQLPFCGPNFIDHFICDLFPLLKLACTDTHIFVILVFANSGSICIIIFSFLLVSYVVILFSLRTHSSEGRRKALSTCGSHITVVVLFFVPCILIYARPTSPFSLEKNVFIFADVLTPLLNPVVYTFRNKEMKNAIRKMWRSLLVAPDILK", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****::****:************:**:********************. .*.**************************.**********:*******************************************************:*:********************************************************************* ****************** **********************************************:******************.*****: ", "identical_positions": 291, "similar_positions": 15, "identity": "93.27%" }, { "cls_id": "homologset.oma.822054", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZV46-1", "uniprot_id": "A0A8I5ZV46_RAT", "id": "A0A8I5ZV46-1", "name": "Olfactory receptor", "aln": "MGSFNASLDKGFMLVGFSDWPELELIFFIYILIFYSVTLFGNTAIIALSRMDLRLHTPMYFFLSHLSFLDLCYTTSTVPQLLINLHGLDRTISYGGCVAQLFISLALGSTESVLLVVMAFDRYAAVCRPLHYTTMMHPVLCQALAIASWVGGFLNSLIQTGLMMAMPLCGHRLNHFFCEMPVFLKLACEDTEGTEAKMFVARVVIVAVPAMLILGSYAQIARAVLRVKSVAARRKAAETCGSHLLVVSLFYGSATYTYLQPKDSYSESKGKFFALFYTIITPMLNPLIYTLRNKDVKGALWKVLGRAAATV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VFA6-1", "uniprot_id": "Q8VFA6_MOUSE", "id": "Q8VFA6-1", "name": "Olfactory receptor", "aln": "MESFNISLGKGFILVGFSDWPALELIFFIYILIFYSLTLFGNTAIIALSRMDLQLHTPMYYFLCHLSFLDLCFTTSTVPQLLINLHGQDRTISYGGCVSQLFITLALGSTESVLLVVMAFDRYAAVCRPLHYMNIMHPVLCQALAIASWVGGFLNSLIQTGLMMAMPLCGHRLNHFFCEMPVFLKLACQDTGGTEAKMFVARAVIVAVPAMLILGSYAQIARAVLKVKSVAARRKAAGTCGSHLLVVSLFYGSATYTYLQPKDSYSESKGKFVALFYTIITPMFNPLIYTLRNKDMKGALWKVLGRAAATG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8C2LIS0-1", "uniprot_id": "A0A8C2LIS0_CRIGR", "id": "A0A8C2LIS0-1", "name": "Olfactory receptor", "aln": "MGNFNSTSQESFILVGFSDWPQLQVFLFVIILVFYSLTVFGNTTIITLARLDLRLHKPMYFFLSNLSFLDLCFTTSTVPQLLINLHGLDRTISYGGCVAQLYIFLALGSTECVLLVVMAFDRYAAVCRPLHYTTIMNPFLCQTLAIVSWGGGFINSLIQTSLMMAMPLCGRQLNHFFCEMPVLLKLACEDTGGTEAKMFVARVVIVACPAMLILGSYVQIARAVLKIKSNTGRRKAFGTCGSHLLVVSLFYGSAIYTYLQPKGSYSESEGKFVALFYTIITPMLNPLIYTLRNKDVKGALWKVLGRGTDSE", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .** : :.*:******** *::::*: **:***:*:****:**:*:*:**:**.***:**.:*******:************** **********:**:* *******.******************** .:*:*.***:***.** ***:******.*********::**********:*****:** **********.**** *********.*******::** :.**** **************** *******.*****:***.**********:***********:**********.: : ", "identical_positions": 241, "similar_positions": 52, "identity": "77.49%" }, { "cls_id": "homologset.oma.822081", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TRC7-1", "uniprot_id": "Q7TRC7_MOUSE", "id": "Q7TRC7-1", "name": "Olfactory receptor", "aln": "MALENASLVTEFILMGLTNRPDLQIPLFLLFLVMYVIATLGNLALIMLIILNSHLHTPMYFFLLNLSCIDLFYCSVITPKMLMNFVLKKNVISYEGCMAQFYFFAFFAISECYVLTTMAYDRYVAICNPLLYNIVMSPKLCSYLMMGTYLMGFSGAMIHTGCILRLTFCDKNTINHYFCDILPLLQISCTSTYVNEIELFIVAGKDIIVPTVIIFTSYGFILSSILKISSTAGMSKAFSTCSSHIIALCLFFGSCTFMYLKPSSVESMDQGKISSVFYNIVVPLMNPLIYSLRNKDVKIAIKKTITKGKF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8C2QEM8-1", "uniprot_id": "A0A8C2QEM8_CRIGR", "id": "A0A8C2QEM8-1", "name": "Olfactory receptor", "aln": "MVLENASLVTEFILVGLTDQPGLQIPLFLLFLVMYMITTMGNLALIVLIVLNSHLHTPMYFFLFNLSCIDLCYCSVITPKMLMNFTLKKNVISYEGCMTQFYFFCFFVISECYVLTAMAYDRYAAICKPLLYNVVMSPKVCSYLMLGSYLMGFSGAMIHTGCVLRLTFCDRNIINHYFCDLLPLLQLSCTSTYVNEIELFIVAGKDIIVPTVIIFTSYGFILSSILKISSTESRSKAFSTCSSHIIAVSLFFGSCAFMYLKPSSAGSMDQGKISSVFYNIVVPMMNPLIYSLRNKDVKIALKKTLTKRKF", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.************:***::*.*************:*:*:******:**:*************:******* *************.************:*****.**.********:******.***:*****:*****:*****:*:**************:*******:* *******:*****:******************************************** . *************:.******:********. *****************:****************:***:** **", "identical_positions": 270, "similar_positions": 34, "identity": "87.1%" }, { "cls_id": "homologset.oma.822661", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O35679-1", "uniprot_id": "ISK4_MOUSE", "id": "O35679-1", "name": "Serine protease inhibitor Kazal-type 4", "aln": "-----------------------MAMHLWL----VTLTLVPLLGMDRELMVSAGSLVFP---RMPFCEHMAELPNCPQTPNLICGTDGLTYENECHLCLTRMKTMKDIQIMKDGQC---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PU35-1", "uniprot_id": "E9PU35_RAT", "id": "E9PU35-1", "name": "", "aln": "-----------------------MAMHLWL----VTLTLVPLLAMDRELPVSAARLVFS---RMPICEHMAEFPNCPRSPNLICGTDGLTYENECHLCVTRMKTKKDIQIMKDGKC---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8C2N0P2-1", "uniprot_id": "A0A8C2N0P2_CRIGR", "id": "A0A8C2N0P2-1", "name": "", "aln": "-----------------------MAMHLWM----VTLTLAGLLAMDSEGQVSAGKLVFS---RMPICEHMAASPKCPKTPELICGTDGVTYKNECYLCVTRIKTKKDIQIMKDGKC---", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "O60575-1", "uniprot_id": "ISK4_HUMAN", "id": "O60575-1", "name": "Serine protease inhibitor Kazal-type 4", "aln": "-----------------------MAVRQWV----IALALAALLVVDREVPVAAGKLPFS---RMPICEHMVESPTCSQMSNLVCGTDGLTYTNECQLCLARIKTKQDIQIMKDGKC---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1SE75-1", "uniprot_id": "F1SE75_PIG", "id": "F1SE75-1", "name": "", "aln": "-----------------------MAVRLWV----VALALAALFIVDREVPVSAEKHVFS---RMPICEHMTESPDCSRIYDPVCGTDGVTYESECKLCLARIENKQDIQIVKDGEC---", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "E7FCI0-1", "uniprot_id": "E7FCI0_DANRE", "id": "E7FCI0-1", "name": "", "aln": "-----------------------MSMGLLV----FGLFLL----------LSSGASGSS---RKPTCAGMPEILACPMNLAPVCGSDGNTYSNECLLCVERLKTKSDILIAKDGDC---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8V0Y6F3-1", "uniprot_id": "A0A8V0Y6F3_CHICK", "id": "A0A8V0Y6F3-1", "name": "", "aln": "MGRGSVTGAGIPTFVPLSLPHAPATSSLWKGWSQLSLNFPPAKLLD-LCSVSGAKLEEGNSLRRPTCGEMAELQACPLVHLPVCGSDGNTYANECLLCVQKMKTRQDIQILSDGECQDI", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * : ::. * * * * *. :**:** ** .** **: :::. .** * .**.* ", "identical_positions": 22, "similar_positions": 18, "identity": "18.49%" }, { "cls_id": "homologset.oma.822662", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P00996-1", "uniprot_id": "ISK1_BOVIN", "id": "P00996-1", "name": "Serine protease inhibitor Kazal-type 1", "aln": "MKVASIFLLTALVLMSLSGNS-GANILGREAKCTNEVNGCPRIYNPVCGTDGVTYSNECLLCMENKERQTPVLIQKSGPC", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A287BPH0-1", "uniprot_id": "A0A287BPH0_PIG", "id": "A0A287BPH0-1", "name": "Serine protease inhibitor Kazal-type 1", "aln": "MKVASIFLLSALALLSLSGYT-RATSPQREATCTSEVSGCPKIYNPVCGTDGITYSNECVLCSENKKRQTPVLIQKSGPC", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "P00995-1", "uniprot_id": "ISK1_HUMAN", "id": "P00995-1", "name": "Serine protease inhibitor Kazal-type 1", "aln": "MKVTGIFLLSALALLSLSGNT-GADSLGREAKCYNELNGCTKIYDPVCGTDGNTYPNECVLCFENRKRQTSILIQKSGPC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09036-1", "uniprot_id": "ISK1_MOUSE", "id": "P09036-1", "name": "Serine protease inhibitor Kazal-type 1", "aln": "MKVAVIFLLSALALLSLAGNTFSAKVTGKEASCHDAVAGCPRIYDPVCGTDGITYANECVLCFENRKRIEPVLIRKGGPC", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***: ****:**.*:**:* : * :**.* . : **.:**:******* **.***:** **::* .:**:*.***", "identical_positions": 44, "similar_positions": 21, "identity": "55.0%" }, { "cls_id": "homologset.oma.822664", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IE49-1", "uniprot_id": "ISK2_RAT", "id": "Q6IE49-1", "name": "Serine protease inhibitor Kazal-type 2", "aln": "----MLRLVLLLLATDFAASDDSLDSSDSQLIKRSQFRTPDCHRFDYPVCSKHLSPVCGTDMNTYGNECTLCMKIREDGSHINIIKDEPC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMY7-1", "uniprot_id": "ISK2_MOUSE", "id": "Q8BMY7-1", "name": "Serine protease inhibitor Kazal-type 2", "aln": "----MLRLVLLLLVTDFAASHETLDSSDSQIMKRSQFRTPDCGHFDFPACPRNLNPVCGTDMNTYSNECTLCMKIREDGSHINIIKDEPC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A287BEN1-1", "uniprot_id": "A0A287BEN1_PIG", "id": "A0A287BEN1-1", "name": "Serine protease inhibitor Kazal-type 1", "aln": "MAPAALRWVLLLLV--WWDSAALLN---AQFGQPSEYRTPSCDQYKLPGCPRDFSPVCGSDMATYPNECTLCMKIREDGRDIKVIQSGPC", "tax_id": 9823, "tax_name": "Pig" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** *****. : * *: :*: : *::***.* ::. * *.:.:.****:** ** ************* .*::*:. **", "identical_positions": 42, "similar_positions": 23, "identity": "46.67%" }, { "cls_id": "homologset.oma.823206", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O70337-1", "uniprot_id": "BIK_MOUSE", "id": "O70337-1", "name": "Bcl-2-interacting killer", "aln": "MSEARLMARDV-IKTVPHDQVPQPP---VASETPSMK--EPVRDVDLMECVEGRNQVALRLACIGDEMDLCLRSPRLVQLPGIAIHRL--AVTYSRTG-VRGIFRSLIRSLTNLRENIWS-WRVLTPGAWVSPDQDPGQLFPMVLLVFLLLGGAWYLQLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13323-1", "uniprot_id": "BIK_HUMAN", "id": "Q13323-1", "name": "Bcl-2-interacting killer", "aln": "MSEVRPLSRDILMETLLYEQLLEPPTMEVLGMTDSEEDLDPMEDFDSLECMEGSDALALRLACIGDEMDVSLRAPRLAQLSEVAMHSLGLAFIYDQTEDIRDVLRSFMDGFTTLKENIMRFWRSPNPGSWVSCEQVLLALLLLLALLLPLLSGGLHLLLK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.* ::**: ::*: ::*: :** * . * * : :*:.*.* :**:** : :************:.**:***.**. :*:* * *. *.:* :*.::**:: .:*.*:*** ** .**:*** :* *: :: *:: **.*. :* *:", "identical_positions": 68, "similar_positions": 53, "identity": "42.5%" }, { "cls_id": "homologset.oma.823278", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F7F5L4-1", "uniprot_id": "F7F5L4_RAT", "id": "F7F5L4-1", "name": "", "aln": "MRRSPCQLPSMALQCLMLLTGLVVGGMSKSTES------------------------------------KAQQPECCMDVVDVNATCLGTGLCGPGCYRHWNADGSASCVRCWNGTLP---TYNGSECRILTGRGMQFPMNRSTGTPGQPHFGGPHVAASLFLGTLFISTGLILSVAGFFYLKRSSKLPEVFYRRDRAPVLQPGETAAMVPLPQSS--------------------------------------------------------------------------------------------------------------------------------------------------VRKPRYIRREQHPEKNRD--PSAFSTVEAHISNV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2ASP7-1", "uniprot_id": "A2ASP7_MOUSE", "id": "A2ASP7-1", "name": "", "aln": "----------MALQCLLLLTGLLTGGVCKSTES------------------------------------QAQQPECCMDVVDFNATCLGTGLCGPGCYRHWNADGSASCVRCWNGTLP---TYNGSECRILTGRGVQLPMNRSTGTPGQPHFGGPHVAASLFLGTLFISTGLILSVAGFFYLKRSSKLPEVFYRRDRAPVLQPGETAAMVPLPQSS--------------------------------------------------------------------------------------------------------------------------------------------------VRKPRYIRREQHPDKNRD--PSAFSTVEAHISNV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3I439-1", "uniprot_id": "G3I439_CRIGR", "id": "G3I439-1", "name": "", "aln": "----------MTLQYLMLLTALLMGGSSKSTES------------------------------------KAQQPECCMNAVDFNATCPGTGLCGPGCYRHWNADGSVSCVRCWNGTFP---TYNGSECRILTGRGMQFPMNRSTGTPGQPHFGGPDVAASLFLGTLFISTGLILSVAGFFYLKRSSKLPEVFYRRDRAPVLQPGETAAMVPLPQSS--------------------------------------------------------------------------------------------------------------------------------------------------VKKPRYIRREQHPDKNRD--PSAFSTVEAHISNV", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q96HA4-1", "uniprot_id": "CA159_HUMAN", "id": "Q96HA4-1", "name": "Uncharacterized protein C1orf159", "aln": "----------MALRHLALLAGLLVGVASKSMENTVTRNSTAVINTQAEGTLSPPGLSSLPVVREWALTHTAQLPECCVDVVGVNASCPGASLCGPGCYRRWNADGSASCVRCGNGTLP---AYNGSECRSFAGPGAPFPMNRSSGTPGRPHPGAPRVAASLFLGTFFISSGLILSVAGFFYLKRSSKLPRACYRRNKAPALQPGEAAAMIPPPQSSGNSSCRIPLWGFPSLGQSQGALWVCPQTGLPGSGSRPPLPGSPGDPPTRQGQGRIWLVPPALDLSWIWPAPPARPPLIPVTSMLFPVPETWGLQERRTHHDRADPQYLLLLEVQLHPRTDAAGLRQALLSSHRFSGAGSGGPKSQPVRKPRYVRRERPLDRATD--PAAFP-GEARISNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A3Q3AP49-1", "uniprot_id": "A0A3Q3AP49_CHICK", "id": "A0A3Q3AP49-1", "name": "", "aln": "----------MEVPYVLLLTRLVAEVASKSTES------------------------------------SVSETECCVDMLESNSSCPVANQCSPGCYRRWNEDGSSSCIKCKNETLPVASVYNLTDCRNTGIRGMNFQMNISTVTPFIQNIGGPEVAASLILGTFFISLFLILSVASFFYLKRANKLPNVFYRRNKASVLQPSETASMIPPPATS--------------------------------------------------------------------------------------------------------------------------------------------------VRKPRYVRRERSLVTSAS--AAMISSSETRVSNV", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "A0A8M1P8K8-1", "uniprot_id": "A0A8M1P8K8_DANRE", "id": "A0A8M1P8K8-1", "name": "", "aln": "----------MSRAYYIISAVLYVLKIPETKAL------------------------------------LDNSNDCCETIKRMNESCANVSLCEPGP-RHVQENGTTFCVPCAS-------ADQGNSTSLNSTRTNQIPVSLIT------VIGGPGVAASVLLGTLLISLGLILSVASFFYLKRSNRLPGVFYRRNKAFIFQPSETAVMIPEASSS--------------------------------------------------------------------------------------------------------------------------------------------------VRKPRYVRRERPSATSTSNSATVATGAVTKVYNV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : * :: . :** * :* .. * ** *: : :*: *: * . . : .. : :. : *.* ****::***::** ******.******:.:** . ***::* :**.*:* *:* . :* *:****:***: . .: . ::: **", "identical_positions": 59, "similar_positions": 51, "identity": "14.9%" }, { "cls_id": "homologset.oma.823306", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "E1BCE8-1", "uniprot_id": "E1BCE8_BOVIN", "id": "E1BCE8-1", "name": "Glutaredoxin domain-containing cysteine-rich protein 1", "aln": "MLKREVKPETDRPRKVRFRIASSHSGRVLREVYEDGRPAGSLDSECASICGLDGLSESDGQQNGHIGSEGDEQENDQDNLLVLARAASEKGFGTRRVNILSKNGTIRGVKYKVSAGQALFNNLTKVLQQPSTELEFDRVVIYTTCLRVVRTTFERCELVRKIFQNHRVKFEEKNIALNGDYGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGELQDLLTKIERVQHPHECPSCGGFGFLPCSVCHGSKMSVFRNCFTDSFKALKCTACNENGLQRCKSCVG", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1S3T4-1", "uniprot_id": "F1S3T4_PIG", "id": "F1S3T4-1", "name": "Glutaredoxin domain-containing cysteine-rich protein 1", "aln": "MLKRDIKPETDRPRKVRFRIASSHSGRVLKEVYDDGRPAGSLDSECASICGIDGLSESDGQQNGHIGSEGDEQENDQDNLLVLARAASEKGFSTRRVNILSKNGTVRGVKYKVSAGQALFNNLTKVLQQPSTDLEFDRVVIYTTCLRVVRTTFERCELVRKIFQNHRVKFEEKNIALNGDYGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGELQDLLTKIERVQHPHECPSCGGFGFLPCSVCHGSKMSVFRNCFTDSFKALKCTACNENGLQRCQSCAG", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A8MXD5-1", "uniprot_id": "GRCR1_HUMAN", "id": "A8MXD5-1", "name": "Glutaredoxin domain-containing cysteine-rich protein 1", "aln": "MLKREMKPESDRPRKVRFRIASSHSGRVLKEVYEDGQPSGSLDSECASICGIDGLGDSDGQQNGHIESEGDENENDQDSLLVLARAASEKGFGTRRVNILSKNGTVRGVKYKVSAGQALFNNLTKVLQQPSTDLEFDRVVIYTTCLRVVRTTFERCELVRKIFQNHRVKFEEKNIALNGEYGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGELQDILTKIERVQHPHECPSCGGFGFLPCSVCHGSKMSMFRNCFTDSFKALKCTACNENGLQRCKNCAG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A048-1", "uniprot_id": "D4A048_RAT", "id": "D4A048-1", "name": "Glutaredoxin domain-containing cysteine-rich protein 1", "aln": "MLRRETKPESDRPRKVRFRIASSHSGRVLKEVYEDGQAPGSLDSECASVCAIDGLSDSEGHQNGHIGLEDNEQEKDQDNLLVLARTASEKAFGTRRVNILSKNGTVRGVKYKVSAGQALFNNLTKVLQQPSADLEFDRVVIYTTCLRVVRTTFERCELVRKIFQNHRVKFEEKNIALNGDYGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGELQDLLTKIERVQHPHECPSCGGFGFLPCSVCHGSKMSVFRNCFTDAFKALKCTACNENGLQRCKNCAC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q50H32-1", "uniprot_id": "GRCR1_MOUSE", "id": "Q50H32-1", "name": "Glutaredoxin domain-containing cysteine-rich protein 1", "aln": "MLRRETKPESDRPRKVRFRIASSHSGRVLKEVYEDGQAPGSLDSECASICAIDGLSDSEGQQNGHIGSEDNEQEKDQDNLLVLARTASEKAFGTRRVNILSKNGTVRGVKYKVSAGQALFNNLTKVLQQPSADLEFDRVVIYTTCLRVVRTTFERCELVRKIFQNHRVKFEEKNIALNGDYGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGELQDLLTKIERVQHPHECPSCGGFGFLPCSVCHGSKMSVFRNCFTDAFKALKCTACNENGLQRCKNCTC", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*: ***:*******************:***:**:..*********:*.:***.:*:*:***** *.:*:*:***.******:****.*.************:*************************::**********************************************:*********************************************:*********************************:*******:*****************:.*. ", "identical_positions": 253, "similar_positions": 33, "identity": "87.24%" }, { "cls_id": "homologset.oma.823390", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1B0GVM5-1", "uniprot_id": "ETDC_HUMAN", "id": "A0A1B0GVM5-1", "name": "Embryonic testis differentiation protein homolog C", "aln": "MDKELPKASPSEPALNIKKSGKSFKCKKPTKNVQVFLINRQLGRNRSDTDLSKWLWMLP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A287BSE1-1", "uniprot_id": "A0A287BSE1_PIG", "id": "A0A287BSE1-1", "name": "", "aln": "MDKEASEVSPSPPTVTIKKKDKSARSEKFSKNVLIFLLGRQLGRHRSDVDLSKWLWMLT", "tax_id": 9823, "tax_name": "Pig" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** .:.*** *::.***..** :.:* :*** :**:.*****:***.*********.", "identical_positions": 36, "similar_positions": 18, "identity": "61.02%" }, { "cls_id": "homologset.oma.823474", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJW3-1", "uniprot_id": "ATPMK_RAT", "id": "Q9JJW3-1", "name": "ATP synthase F(0) complex subunit k, mitochondrial", "aln": "MAGPESDGQFQFTGIKKYFNSYTLTGRMNCVLATYGGIALLVLYFKLRPKKTPAVKAT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8L2QV13-1", "uniprot_id": "A0A8L2QV13_RAT", "id": "A0A8L2QV13-1", "name": "", "aln": "MAGPESDGQFQFTGIKKYFNSYTLTGRMNCVLATYGGIALLVLYFKLRPKKTAAVKAT", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************************************************.*****", "identical_positions": 57, "similar_positions": 1, "identity": "98.28%" }, { "cls_id": "homologset.oma.827458", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NR45-1", "uniprot_id": "SIAS_HUMAN", "id": "Q9NR45-1", "name": "N-acetylneuraminate-9-phosphate synthase", "aln": "MPLELELCPGRWVGGQHPCFIIAEIGQNHQGDLDVAKRMIRMAKECGADCAKFQKSELEFKFNRKALERPYTSKHSWGKTYGEHKRHLEFSHDQYRELQRYAEEVGIFFTASGMDEMAVEFLHELNVPFFKVGSGDTNNFPYLEKTAKKGRPMVISSGMQSMDTMKQVYQIVKPLN-PNFCFLQCTSAYPLQPEDVNLRVISEYQKLFPDIPIGYSGHETGIAISVAAVALGAKVLERHITLDKTWKGSDHSASLEPGELAELVRSVR-------------LVERALGSP----------TKQLLPCEMACNEKLGKSVVAKVKIPEGTILTMDMLTVKVGEPKGYPPEDIFNLVGKKVLVTVEEDDTIMEELVDNHGKKIKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8C2N8U5-1", "uniprot_id": "A0A8C2N8U5_CRIGR", "id": "A0A8C2N8U5-1", "name": "N-acetylneuraminate-9-phosphate synthase", "aln": "MPLELELCPGRWVGGQHPCFIIAEIGQNHQGDLDIAKRMIRTAKECGADCAKFQKSELEFKFNRKALERPYTSKHSWGTTYGEHKRHLEFSHAQYKELQRYAQEIGIFFTASGMDEMAVEFLHELNVPFFKVGSGDTNNFPYLEKTAKKGRPMVISSGMQSMDTMKQVYQIVKPLN-PNFCFLQCTSAYPLQPEDANLRVISEYQKLFPDIPIGYSGHETGIAISVAAVALGAKVLERHITLDKTWKGSDHSASLEPGELAELVRSVR-------------LVERALGSP----------TKQLLPCEMACNEKLGKSVVAKVRIPEGTVLTLDMLTVKVGEPKGYPPEDIFNLVGKKMLVTVEEDDTILEDSVENHSKKIKS", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "B1WC26-1", "uniprot_id": "B1WC26_RAT", "id": "B1WC26-1", "name": "N-acetylneuraminate-9-phosphate synthase", "aln": "MPLELELCPGRWVGGQHPCFIIAEIGQNHQGDLDVAKRMIRTAKECGADCAKFQKSELEFKFNRKALERPYTSKHSWGKTYGEHKRHLEFSHDQYKELQSYAQEIGIFFTASGMDEMAVEFLHELNVPFFKVGSGDTNNFPYLEKTAKKGRPMVISSGMQSMDTMKQVYQIVKPLN-PNFCFLQCTSAYPLQPEDANLRVISEYQKLFPDIPIGYSGHETGIAISVAAVALGAKVLERHITLDKTWKGSDHLASLEPGELAELVRSVR-------------LVERALGSP----------AKQLLPCEMACNEKLGKSVVAKVKIPAGTILTLDMLTVKVGEPKGYPPEDIFNLVGKKVLVTIEEDDTVMEESVESQSKKIKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J77-1", "uniprot_id": "SIAS_MOUSE", "id": "Q99J77-1", "name": "N-acetylneuraminate-9-phosphate synthase", "aln": "MPLELELCPGRWVGGKHPCFIIAEIGQNHQGDIDVAKRMIRTAKECGADCAKFQKSELEFKFNRKALERPYTSKHSWGKTYGEHKRHLEFSHDQYKELQSYAQEIGIFFTASGMDEMAVEFLHELNVPFFKVGSGDTNNFPYLEKTAKKGRPMVISSGMQSMDTMKQVYQIVKPLN-PNFCFLQCTSAYPLQPEDANLRVISEYQKLFPDIPIGYSGHETGIAISVAAVALGAKVLERHITLDKTWKGSDHSASLEPGELAELVRSVR-------------LVERALGSP----------TKQLLPCEMACNEKLGKSVVAKVKIPAGTTLTLDMLTVKVGEPKGYPPEDIFNLAGKKVLVTIEEDDTVMEESVESHSKKIKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VG74-1", "uniprot_id": "SIAS_DROME", "id": "Q9VG74-1", "name": "N-acetylneuraminate-9-phosphate synthase", "aln": "MLLN-DIISGKLVD---SVYIIAEIGQNHQGCVETAKKMIWEAKKAGCHCVKFQKSDLPAKFTRSALDREYISDHAWGKTYGEHKEYLEFSKDQYLQLQAHCKELNVDFTASAMDERSLEFLSALNVPFIKIGSGDANNFPLLKKAANLNLPLVISTGMQTMQTVERIVQTMRESGKEDYALMHCVSSYPTDPKDCSLQLISVLRTRFPNVAIGYSGHELGVIISQAAVLLGARIVERHFTLDKSQKGSDHRCSLEPQELKALTTAITNFKLSSVPMPPQEIVKKLNGDEELEAALQHVESKTILPCELPCRNKLGKSIVAARNLNKGYRLQLADMAIKVSEPSGLTAEDFLDLVGKELADNIGEDEPILGNSIIN-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *: :: .*: *. . :*********** :: **:** **:.*..*.*****:* **.*.**:* * *.*:**.******.:****: ** :** :.:*:.: ****.*** ::*** *****:*:****:**** *:*:*: . *:***:***:*:*:::: * :: . ::.:::*.*:** :*:* .*::** :. **::.******* *: ** *** ***:::***:****: ***** .**** ** *. :: :*:: *. :* :****:.*.:*****:** .: * * : :::**.**.* ..**:::*.**:: .: **:.:: : : . ", "identical_positions": 167, "similar_positions": 118, "identity": "43.6%" }, { "cls_id": "homologset.oma.827478", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6MGB5-1", "uniprot_id": "DHB8_RAT", "id": "Q6MGB5-1", "name": "(3R)-3-hydroxyacyl-CoA dehydrogenase", "aln": "-MASQLR-------------------------------------------------------------------LRSALALVTGAGSGIGRAISVRLAAEGAAVAA-CDLDGAAAQDTVRLLGNPGSEDREPRGKHAAFQADVSEGPAAKRLLEQVQACFFRPPSVVVSCAGITRDEFLLHMSEED--------------WDRVIAVNLKGTFLVTQAAAQALVSSGGR-GSIINISSIVGKVGNIGQTNYASSKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKMPEKVKDKVTAMIP-----------LGHMGDPEDVADVVAF---------------LASEDS---GYITGASVEVSGGLFM--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50171-1", "uniprot_id": "DHB8_MOUSE", "id": "P50171-1", "name": "(3R)-3-hydroxyacyl-CoA dehydrogenase", "aln": "-MASQLR-------------------------------------------------------------------LRSALALVTGAGSGIGRAISVRLAAEGAAVAA-CDLDGAAAQDTVRLLGSPGSEDGAPRGKHAAFQADVSQGPAARRLLEEVQACFSRPPSVVVSCAGITRDEFLLHMSEED--------------WDRVIAVNLKGTFLVTQAAAQALVSSGGR-GSIINISSIIGKVGNIGQTNYASSKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKMPEKVKDKVTAMIP-----------LGHMGDPEDVADVVAF---------------LASEDS---GYITGASVEVSGGLFM--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A061ILV4-1", "uniprot_id": "A0A061ILV4_CRIGR", "id": "A0A061ILV4-1", "name": "(3R)-3-hydroxyacyl-CoA dehydrogenase", "aln": "-MASQLR-------------------------------------------------------------------LRSALALVTGAGSGIGRAISVRLAQEGAAVAA-CDLDGAAAQDTVRLLGGPGSEGGAPRGKHAAFQADVSQAAAARRLLEQVQACFSRPPSVVVSCAGITRDEFLLHMSEED--------------WDRVIAVNLKGTFLVTQAAAQALVSSGCR-GSIINISSIIGKVGNIGQTNYASSKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKMPEKVKDKVTAMIP-----------LGHMGDPEDVADAVAF---------------LASEDS---GYITGATVEVTGGLFM--------------------", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q92506-1", "uniprot_id": "DHB8_HUMAN", "id": "Q92506-1", "name": "(3R)-3-hydroxyacyl-CoA dehydrogenase", "aln": "-MASQLQNR-----------------------------------------------------------------LRSALALVTGAGSGIGRAVSVRLAGEGATVAA-CDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDD--------------WDKVIAVNLKGTFLVTQAAAQALVSNGCR-GSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIP-----------MGHLGDPEDVADVVAF---------------LASEDS---GYITGTSVEVTGGLFM--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "K7GLG0-1", "uniprot_id": "K7GLG0_PIG", "id": "K7GLG0-1", "name": "(3R)-3-hydroxyacyl-CoA dehydrogenase", "aln": "-MPPSLP--------------------------------------------------------------------PRVFSPTSGAGSGIGRAVSVRLAAEGAAVAA-CDLDGAAAQETVQLLGGPGSEKGAPSGAHAAFQADVSEAETARRLLEQVQAYFFRPPSVVVSCAGITRDEFLLRMSEDD--------------WDKVIAVNLKGIFLVTQAAAQALVSSGCP-GSIINISSIIGKVGNMGQTNYAASKAGVIGLTQAVARELGRYRIRCNSVLPGFIKTPMAQKVPQKVLDKMWPMWSRSWHLRTVDTSQGHQSKSLEVFSCNCLKDPGLCSLPHHSARPPADEDSEFPGYKRGGSVWLKNAEYGRQGCL---------------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A8V0XCB1-1", "uniprot_id": "A0A8V0XCB1_CHICK", "id": "A0A8V0XCB1-1", "name": "(3R)-3-hydroxyacyl-CoA dehydrogenase", "aln": "-MGSAGR-------------------------------------------------------------------LGGVVALVTGGGSGIGRAVCVRLARDGARVAV-ADRDGGWAGEVREGLSP------TPPPLHAAFAVDVASQDSVDAMVARVQDHFGTPPSICVTCAGVTRDEFLLRLPHNH--------------FDEVLSVNLKGTFLVTQAVARAMVAVGAARGSIVHVGSIVGKVGNVGQANYAASKSGVEGLMRSCAKELGRFGIRCNAVLPGFIRTPMTARVPSKVIGKFAALVP-----------MGRLGQPEEVADVCAF---------------LASEDS---AYITGASVEVTALLRERLTSQPNHLIGSLTDCSRAT", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9W4U2-1", "uniprot_id": "Q9W4U2_DROME", "id": "Q9W4U2-1", "name": "Ketoreductase domain-containing protein", "aln": "-MSVGVL--------------------------------------------------------------------AGKVALVTGAGSGIGRATCRLLARDGAKVIA-VDRNLKAAQETVQELGS---------ERSAALEVDVSSAQSVQFSVAEALKKFQQAPTIVVNSAGITRDGYLLKMPERD--------------YDDVYGVNLKGTFLVTQAYAKAMIEQKLENGTIVNLSSIVAKMNNVGQANYAATKAGVISFTEVASKEFGKFGIRVNCILPGYIDTPMVAVVPDSVKQEVVQRCP-----------LGRLGQPEEIAEVIAF---------------LASPQS---SYVNGAAIEVTGGLK---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33207-1", "uniprot_id": "FABG_ARATH", "id": "P33207-1", "name": "3-oxoacyl-[acyl-carrier-protein] reductase, chloroplastic", "aln": "-MAAAVAAPRLISLKAVAKLGFREISQIRQLAPLHSAIPHFGMLRCRSRQPFSTSVVKAQATATEQSPGEVVQKVESPVVVITGASRGIGKAIALALGKAGCKVLVNYARSAKEAEEVAKQIEEYG-------GQAITFGGDVSKATDVDAMMKTALDKWG-TIDVVVNNAGITRDTLLIRMKQSQ--------------WDEVIALNLTGVFLCTQAAVKIMMK--KKRGRIINISSVVGLIGNIGQANYAAAKGGVISFSKTAAREGASRNINVNVVCPGFIASDMTAELGEDMEKKILGTIP-----------LGRYGKAEEVAGLVEFLA-------------LSPAAS----YITGQAFTIDGGIAI--------------------", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q55E82-1", "uniprot_id": "Q55E82_DICDI", "id": "Q55E82-1", "name": "3-oxoacyl-[acyl-carrier-protein] reductase", "aln": "MFKNSIKR---------------------------------------------------------------LFELKGKNAIVTGGTRGIGYQIALDLANKGANVFVWSRNKEVNEKAVKSLPIIHNDQKHTGIVCDLSKTNKLDETINEIKKQVSSFNNGDNKIGILVHSAGITHSELLFKKSSNDNNNYNNNYNSINDNSNEIMTTNLLSPILITQSFLKDMMR--LKYGRIIFIGSVVSEMGNRGQTIYSSSKGGLNGFSKSLSKEIGQFNCTSNVISPGFIDTDMSQQY---INNELINSIP-----------LKRIGNTKDISKTALF-----------------LIES---DYITGQNIRVDGGLY---------------------", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*. *** . *. *. * . . . : .: . : * **:*:. *:: . : : ** . :* **: : :: * *: :.*::. :.* **: *:::*.*: .: . ::* . * : **:* : * : :. . : ... :: : * * * . : ", "identical_positions": 35, "similar_positions": 64, "identity": "8.93%" }, { "cls_id": "homologset.oma.827480", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "K7GP28-1", "uniprot_id": "K7GP28_PIG", "id": "K7GP28-1", "name": "3-hydroxyacyl-CoA dehydrogenase type-2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MAAACRSVKVTGFSPLLLAPLPRLGWRGRRTKRKRSVLGEKGLVAIITGGASGLGLATAERLVGQGASAVLLDLPHSDGEAQAKKLG-KSCAFAPADVTSEKDVQAALTLAKEKFGRVDVAVNCAGIGVASKTYNLKKSQAHTLEDFQRVLNVNLTGTFNVIRLVAGEMG-QNEP------DQGGQRGVIINTASIAAFEGQVGQAAYSASKGGIVSMTLPIARDLAPMGIRVMTIAPGLFGTPLLNTLPDKVRNFLANQVPFPSRLGDPAEYAHLAQVIIENPFLNGEVIRLDGAIRMQP-", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "O02691-1", "uniprot_id": "HCD2_BOVIN", "id": "O02691-1", "name": "3-hydroxyacyl-CoA dehydrogenase type-2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MAAACRSVK--------------------------------GLVALITGGASGLGLATAERLVGQGATAVLLDLPNSDGETQAKKLG-KSCAFAPADVTSEKDVQAALTLAREKFGRVDVAVNCAGIAVASKTYNLKKSQAHTLEDFQRVINVNLIGTFNVIRLVAGEMG-QNEP------DQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPMGIRVMTIAPGLFGTPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQAIIENSFLNGEVIRLDGAIRMQP-", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q99714-1", "uniprot_id": "HCD2_HUMAN", "id": "Q99714-1", "name": "3-hydroxyacyl-CoA dehydrogenase type-2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MAAACRSVK--------------------------------GLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLG-NNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMG-QNEP------DQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENPFLNGEVIRLDGAIRMQP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3H7U0-1", "uniprot_id": "G3H7U0_CRIGR", "id": "G3H7U0-1", "name": "3-hydroxyacyl-CoA dehydrogenase type-2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MAAACRSVK--------------------------------GLVAVITGGASGLGLATAERLVGQGATAVLLDLPNSGGEAQAKKLG-ESCLFAPANVTSEKDVQAALTLAKEKFGRVDVAVNCAGIAVAIKTYNQKRNQAHTLEDFQRVLNVNLLGTFNVIRLVAGEMG-QNEP------DQGGQRGVIINTASVAAFDGQVGQAAYSASKGGIVGMTLPIARDLAPLGIRVMTIAPGLFATPLLTTLPEKVQNFLASQVPFPSRLGDPAEYAHMVQTIIENPFLNGEVIRLDGAIRMQP-", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "O70351-1", "uniprot_id": "HCD2_RAT", "id": "O70351-1", "name": "3-hydroxyacyl-CoA dehydrogenase type-2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAVRSVK--------------------------------GLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLG-GNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMG-QNEP------DQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENPFLNGEVIRLDGAIRMQP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8V0X2T8-1", "uniprot_id": "A0A8V0X2T8_CHICK", "id": "A0A8V0X2T8-1", "name": "3-hydroxyacyl-CoA dehydrogenase type-2", "aln": "MAAPPPPPPPLPTGVPIPSPAAARLHSAPLCSTRQFSAPLGSSLLYSAILGSTRLLFALLGNSRLHSAPLDSTGHCSAPPTAPQLHQSPLSSFRLRPHSAPPGSARLSSCIPSPIPAHRPSVPPITFPLFMAPPISALLRSAPPATLRLLPPPPPTTIGPTMAALRSVK--------------------------------GMVALVTGGASGLGRATAERLVEQGARVVLLDLPSSQGAQLAAELG-ERCAFAPANVTSAEEVEAALALAKKTFGKLELTVNCAGVGIAVKTYNAKKDKVHELEDFQRVINVNLVGTFNVIRLSARLMS-QNTP------DPDGHRGLVVNTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPLGIRVVTIAPGLFSTPLLAGLPEKVRNFLGQQVPFPSRLGNPSEYAHLVQALAENPMINGEVVRLDGALRMQP-", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "O18404-1", "uniprot_id": "HCD2_DROME", "id": "O18404-1", "name": "3-hydroxyacyl-CoA dehydrogenase type-2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------MIK--------------------------------NAVSLVTGGASGLGRATAERLAKQGASVILADLPSSKGNEVAKELG-DKVVFVPVDVTSEKDVSAALQTAKDKFGRLDLTVNCAGTATAVKTFNFNKNVAHRLEDFQRVININTVGTFNVIRLSAGLMG-ANEP------NQDGQRGVIVNTASVAAFDGQIGQAAYSASKAAVVGMTLPIARDLSTQGIRICTIAPGLFNTPMLAALPEKVRTFLAKSIPFPQRLGEPSEYAHLVQAIYENPLLNGEVIRIDGALRMMP-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q86JE3-1", "uniprot_id": "Q86JE3_DICDI", "id": "Q86JE3-1", "name": "Ketoreductase domain-containing protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MKIN--------------------------------GKTFVVTGGASGLGLETSRHLRSLGANIFIMDMNEENGRKVVEELGSDKTMFSSVDITLEDSVKLSLEHCLKKFKEIHGVINCAGVAAAQRVIK-RDGQVHPLDLFTRVVMVNLIGTFNVIRLVADIIHNQNQPSSKDGGEEEEEKGVFIMTASVAAFEGQVGQSAYSASKSGVVGMTLPMAREFATLKIRINTIAPGTFETPMVEMLPQAAIKSINESIPFPSRMGKPKEFAFLCQHLIENTYINGEVIRLDGALRLSKL", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . . ::******** *:.:* ** .: *: . * . :** * ..::* ..*. :* . .* .:. .:**** . * :. : . . .* *: * **: :* ******** * : * * : .:*:.: ***:***:**:**:******..:*.****:**:::. **: ***** * **:: **: . . : ..:***.*:*.* *:*.: * : **. :****:*:***:*: ", "identical_positions": 99, "similar_positions": 83, "identity": "21.43%" }, { "cls_id": "homologset.oma.827481", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3U0B3-1", "uniprot_id": "DHR11_MOUSE", "id": "Q3U0B3-1", "name": "Dehydrogenase/reductase SDR family member 11", "aln": "----------------------------------------------------------------------MTRAGMERWRDRLALVTGASGGIGAAVARALVQQG---LKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDLSNEEDILSMFSAVRSQHSGVDICINNAGMAR-PDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNIDDGHIININSMCGHRVPPQSVIHFYSATKYAVTALTEGLRQELLEAQTHIRATCISPGLVETQFAFKLHDKDPGEAAATYEHIKCLRPEDVAEAVIYVLSTPPHVQVGDIQMRPTEQVT-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V978-1", "uniprot_id": "G3V978_RAT", "id": "G3V978-1", "name": "Dehydrogenase/reductase SDR family member 11", "aln": "MWPSVEVPRAEPRPEAGPQGVGSRRSSNISKLPAPAPAVTRELPSFSNSRLNSAIPVPSSPNEVGRRLGTMTRAGMERWRDRLALVTGASGGIGAAVARALVQQG---LKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDLSNEEDILSMFSAVRSQHSGVDICINNAGMAR-PDSLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININSMCGHRVPPQSVIHFYSATKYAVTALTEGLRQELLEAQTHIRATCISPGLVETQFAFKLYDKDPREAAATYEHIKCLRPEDVAEAVIYVLSTPPHVQVGDIQMRPTEQVT-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UWP2-1", "uniprot_id": "DHR11_HUMAN", "id": "Q6UWP2-1", "name": "Dehydrogenase/reductase SDR family member 11", "aln": "----------------------------------------------------------------------MARPGMERWRDRLALVTGASGGIGAAVARALVQQG---LKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLAR-PDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFAFKLHDKDPEKAAATYEQMKCLKPEDVAEAVIYVLSTPAHIQIGDIQMRPTEQVT-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5WUM7-1", "uniprot_id": "A5WUM7_DANRE", "id": "A5WUM7-1", "name": "Dehydrogenase/reductase SDR family member 11", "aln": "------------------------------------------------------------------------MIMMERWKGRVALVTGASVGIGAAVARALVQHG---MKVVGCARNVDKIEKLAAECQSAGYSGILIPYKCDLCNEEEILSMFSAIKTLHQGVDVCINNAGLAH-NEPLLSGRTDGWRNMIDVNILALAICTREAYQSMRERHVDDGHIININSMGGHRMVSSADEHFYCATKYAVTAMTEGLRQELREAKTHIRATCISPGIVETEFAFRHHNSDPERAAAVYESIKCLKAEDIASAVTYVLSAPAHVQIGDVQMRPVDQVS-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q71R50-1", "uniprot_id": "DHR11_CHICK", "id": "Q71R50-1", "name": "Dehydrogenase/reductase SDR family member 11", "aln": "---------------------------------------------------------------------------MERWTGRVALVTGASVGIGAAVARALVQHG---MKVVGCARSVDKIEKLAAECQSAGYPGTLIPYKCDLSNEEEILSMFSAIKTLHQGVDVCINNAGLAR-PEPLLSGKTEGWRTMIDVNVMAVSICTREAYQSMKERNIDDGHIININSMNGHSVVPQSVVHFYSATKYAVTALTEGLRQELREAKTHIRATCISPGLVETGFAFKLHDNDPERAAATYESIRCLKAEDMANAVIYVLSAPPHVQIGDIQMRPTEQIS-------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q05016-1", "uniprot_id": "YM71_YEAST", "id": "Q05016-1", "name": "NADP-dependent 3-hydroxy acid dehydrogenase", "aln": "--------------------------------------------------------------------MSQGRKAAERLAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNAKVHVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIATEDIQDVFDTNVTALINITQAVLPIFQAKNSGD--IVNLGSIAGRDAYP--TGSIYCASKFAVGAFTDSLRKELIN--TKIRVILIAPGLVETEFSLVRYRGNEEQAKNVYKDTTPLMADDVADLIVYATSRKQNTVIADTLIFPTNQASPHHIFRG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : .*:**** *** *.* :: . :*:: .** : ::*:* .. . : : *: : *.* .::. : ...:*: :**** * : : . *.. : :::.*: *: *: . :: :: .* *:*:.*: *: . :*.*:*:** *:*:.**:** : *:**. *:**:*** *:: : : .* .*: * .:*:*. : *. * : :.* : *.:* : ", "identical_positions": 66, "similar_positions": 92, "identity": "19.35%" }, { "cls_id": "homologset.oma.827482", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P51659-1", "uniprot_id": "DHB4_HUMAN", "id": "P51659-1", "name": "Peroxisomal multifunctional enzyme type 2", "aln": "MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEE-GEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFEN-----ASKPQSIQESTGSIIEVLSKID-SEGGVSANHTSRATSTATSG----------FAGAIGQKLPP--FSYAYTELEAIMYALGVGASIKDPKDLK-----FIYEGSSDFS---CLPTFGVIIGQKSMMGGG-----------LAEIPGLSINFAKVLHGEQYLELYKPLPRA------GKLKCEAVVADVLD-------KGSGVVIIMDVYS-----------YSEKELICHNQFS-------------------------LFLVGSGGFGGK---RTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWN---PLHIDPNFASLAGFDKPILHG------LCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAK---TPSEGG--------------KLQSTFVFEEIGRRLKDIGPEVVKKVN-------AVFEWHITKGGNIGAKWTIDLKSGSGKVYQGP------------AKGAADTTIILS----------------------DEDFMEVVLG----KLDPQK----AFFSGRLKARGNIMLSQKLQMILKDYAKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P51660-1", "uniprot_id": "DHB4_MOUSE", "id": "P51660-1", "name": "Peroxisomal multifunctional enzyme type 2", "aln": "MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVAEIRRKGGKAVANYDSVEA-GEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIHRVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCNTLAIEGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWEKICDFSN-----ASKPQTIQESTGGIVEVLHKVD-SEG-ISPNRTSHAAPAATSG----------FVGAVGHKLPS--FSSSYTELQSIMYALGVGASVKNPKDLK-----FVYEGSADFS---CLPTFGVIVAQKSMMNGG-----------LAEVPGLSFNFAKALHGEQYLELYKPLPRS------GELKCEAVIADILD-------KGSGVVIVMDVYS-----------YSGKELICYNQFS-------------------------VFVVGSGGFGGK---RTSEKLKAAVAVPNRPPDAVLRDATSLNQAALYRLSGDWN---PLHIDPDFASVAGFEKPILHG------LCTFGFSARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGDVVISNAYVDLVPASGVSTQ---TPSEGG--------------ELQSALVFGEIGRRLKSVGREVVKKAN-------AVFEWHITKGGTVAAKWTIDLKSGSGEVYQGP------------AKGSADVTIIIS----------------------DEDFMEVVFG----KLDPQK----AFFSGRLKARGNIMLSQKLQMILKDYAKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "I3LEF8-1", "uniprot_id": "I3LEF8_PIG", "id": "I3LEF8-1", "name": "Peroxisomal multifunctional enzyme type 2", "aln": "MASMLNFYGRVVLVTGAGGGLGRTYALAFAERGASVVVNDLGGDMKGVGKGSLAADKVVEEIRRKGGKAVANYDSVEA-GEKIVKAALDAFGRIDVVVNNAGILRDRSFSRISDEDWDMIQRVHLRGSFMVTRAAWDHMKKQNFGRIIMTSSAAGIYGNFGQANYSAAKLGLLGLSNSLAVEGKKNNIHCNTVAPVAGSRMTQGFLPEDLIEALKPEYVAPLVLWLCHESCEENGSVFEVGAGWIGKLRWERTLGALVRQKNQPMTPEAVKANWTKICDFDN-----ATKPQRIQDSVSTVIEALSKIDSSDGGISANNLSHATSAAPSG----------LVEAVGYKFPP--FSSSYTEVDTIMYALGVGASIKEPKDLK-----FIYEGNSDFS---CLPTFGVILAQKSLGGGG-----------LAEIPGLSVNFTKVLHGEHYLELYKPLPNA------GDLKCEAVVADVLD-------KRSGLVILIDVYS-----------YSGKELICYNQFS-------------------------VFVMGSGGFGGK---RTSDKDKVAVAIPSRPPDAILTDTTSLNQAALYRLSGDWN---PLHIDPDFASLAGFDRPILHG------LCTFGFSARHVLQQYADRDVLRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDTVISNAYVDLVPTSDTLAK---IPSEGG--------------DLQSNLVFEEIGRRLQDIGQEMVKKVN-------AVFEWHITKGEKIAAKWTIDLKNGAGKVYQGP------------AKGSADATFILS----------------------DEVFMEVVLG----KLDPQK----AFFSGRLKARGNIMLSQKLQMILKDYAKI", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q02207-1", "uniprot_id": "FOX2_YEAST", "id": "Q02207-1", "name": "Peroxisomal hydratase-dehydrogenase-epimerase", "aln": "MPGNLSFKDRVVVITGAGGGLGKVYALAYASRGAKVVVNDLGGTLGGSGHNSKAADLVVDEIKKAGGIAVANYDSVNENGEKIIETAIKEFGRVDVLINNAGILRDVSFAKMTEREFASVVDVHLTGGYKLSRAAWPYMRSQKFGRIINTASPAGLFGNFGQANYSAAKMGLVGLAETLAKEGAKYNINVNSIAPLARSRMTENVLPPHILKQLGPEKIVPLVLYLTHESTKVSNSIFELAAGFFGQLRWERSSGQIFNPDPKTYTPEAILNKWKEITDYRDKPFNKTQHPYQLSDYNDLITKAKKLPPNEQGSVKIKSLCNKVVVVTGAGGGLGKSHAIWFARYGAKVVVNDIKDPFSVVEEINKLYGEGTAIPDSHDVVTEAPLIIQTAISKFQRVDILVNNAGILRDKSFLKMKDEEWFAVLKVHLFSTFSLSKAVWPIFTKQKSGFIINTTSTSGIYGNFGQANYAAAKAAILGFSKTIALEGAKRGIIVNVIAPHAETAMTKTIFSEKELSNHFDASQVSPLVVLLASEELQKYSGRRVIGQLFEVGGGWCGQTRWQRSSGYVSIKETIEPEEIKENWNHITDFSRNTINPSSTEESSMATLQAVQKAHSSKELDDGLFKYTTKDCILYNLGLGCTSKELKYTYENDPDFQVLPT-FAVIPFMQATATLAMDNLVDNFNYAMLLHGEQYFKLCTPTMPSNGTLKTLAKPLQVLDKNGKAALVVGGFETYDIKTKKLIAYNEGSFFIRGAHVPPEKEVRDGKRAKFAVQNFEVPHGKVPDFEAEISTNKDQAALYRLSGDFNPLHIDPTLAKAVKFPTPILHGLCTLGISAKALFEHYGPYEELKVRFTNVVFPGDTLKVKAWKQGSVVVFQTIDTTRNVIVLDNAAVKLSQAKSKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . * * .***::****.***:.****:*.*** *:****** : * *:.* *** ** **:: ** ********: ***::::*:. ***:**::******** **:::::.:: : *** *.: ::**** :*:.*::***: *:*.:*::************:*::**.::** ** * **: *::** * ****: .:* .::: * ** :.****:* *** : ...:**:.**::*:*****: * :.. :. ****: :* :* *: : : :* :.: . : :. .:* :. : .. . ..... * *. :. .:: :: * * *::: :.:*: :: . :.*. * . . *: :**: * . .** . : :: : :. . : *. : *. * :*. : : *:::* : :* *** : : * :* :*.* * . *:* . :: . . . *.:.: :: * : . .*: . * :: ::: * .:*:.. ::: .: *:.: . ** : * * : :.::: :: :... : : . :: .:.* . :. :.: * . ::. *:.. ** ::.:.:* : *. :.. . :*: . **. * *: . * :**: *:.. * ..*. .:*. *:*.: : : :*:", "identical_positions": 209, "similar_positions": 273, "identity": "23.2%" }, { "cls_id": "homologset.oma.827483", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2M4-1", "uniprot_id": "DECR2_RAT", "id": "Q9Z2M4-1", "name": "Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]", "aln": "MTQQP-------PDVEEDDCLSEYHHLFCPDLLQDKVAFITGGGSGIGFRIAEIFMRHGCHTVIVSRSLPRVSEAAKKLVAATGKRCLPLSMDVRVPPAVMAAVDQALKEFGKIDILINCAAGNFLCPASALSFNAFKTVVDIDTLGTFNVSRVLYEKFFR--------DHGGVIVNITATLSMRGQVLQLHAGAAKAAVDAMTRHLAVEWGPQ-NIRVNSLAPGAISGTEGLRRLGGPKASSKFKYLSSPIPRLGTKTEIAHSVLYLASPLASYVSGIVLVVDGGSWMTLP-----NDIGRLLEFESS----------SAKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV68-1", "uniprot_id": "DECR2_MOUSE", "id": "Q9WV68-1", "name": "Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]", "aln": "MAQPP-------PDVEGDDCLPEYHHLFCPDLLQDKVAFITGGGSGIGFRIAEIFMRHGCHTVIVGRSLQKVTTAAKKLVAATGKRCLPLSMDVRVPPEVMTAVDQALQEFGKINILINCAAGNFLCPASALSFNAFKTVVDIDTIGTFNVSSVLYKKFFR--------DHGGVIVNITATLSMRGQVLQLHAGAAKAAVDAMTRHLAVEWGPQ-NIRVNSLAPGAISGTEGLRRLRGSNASSKLKHFSNPIPRLGTKTEIAHSVLYLASPLASYVSGIVLVVDGGSWMTFP-----NGIKQLLEFESF----------SAKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NUI1-1", "uniprot_id": "DECR2_HUMAN", "id": "Q9NUI1-1", "name": "Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]", "aln": "MAQPP-------PDVEGDDCLPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFR--------DHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQ-NIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGGAWLTFP-----NGVKGLPDFASF----------SAKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NV34-1", "uniprot_id": "DECR2_DANRE", "id": "Q6NV34-1", "name": "Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]", "aln": "MAEKPQLVNNLPEDVETDECMNKYTHIYSPDLLSDQVAFITGGGSGIGFRIAEVLMRHGCDTVIASRNLEKISQAAKKLTSTTGRRCLPIAMDVRQPETILAAVDETLKTFGRVDILINNAAGNFLCPATSLSFNAFKTVMEIDTMGTFNTSKVIYDKWFK--------DHGGSIVNISATLGYRGQALQVHAGSAKAANDAMTRHLAVEWGPS-GVRVNTVAPGPISGTEGYRRLGGSHAETAGAFHSIPLQRAGNKTEMAHAVLFLASRASSYVTGSVLVADGGAWLTSA-----NDVERLLGIVSSR---------SAKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9LTV6-1", "uniprot_id": "DECR2_ARATH", "id": "Q9LTV6-1", "name": "Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]", "aln": "MDSP-----------------------FKPDVVRGQVALITGGGSGIGFEISSQFGKHGASIAIMGRRKQVLDDAVSALR-SLGIQAIGLEGDVRKQEDARRVVEATFQHFGKLDILVNAAAGNFLAAAEDLSPNGFRTVLDIDAVGTFNMCHAALKYLKKGAPGRDSSSGGGSIINISATLHYTASWYQIHVSAAKAAVDATTRNLALEWGTDYDIRVNGIAPGPIGGTPGMSKLVPEEIENKTREY-MPLYKVGEKWDIAMAALYLSCDSGKYVSGLTMVVDGGLWLSKPRHLPKEAVKQLSRAVEKRSRAKPVGLPTSKL", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : **:: .:**:**********.*:. : :**. .* .* : *. * : * :.: : *** .*: ::: **:::**:* ******..* ** *.*:**::**: **** . . . : . ** *:**:*** .. *:*..:**** ** **:**:***.. .:*** :***.*.** * :* . . *: : * * ::* :.*:*:. ..**:* .:*.*** *:: . : : * . ::**", "identical_positions": 102, "similar_positions": 86, "identity": "31.58%" }, { "cls_id": "homologset.oma.827484", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O70503-1", "uniprot_id": "DHB12_MOUSE", "id": "O70503-1", "name": "Very-long-chain 3-oxoacyl-CoA reductase", "aln": "-------MECAPPAAG------FLYWVGASTIAYLALRASYSLFRAFQVWCVGNEALVGPRLGEWAVVTGGTDGIGKAYAEELAKRGMKIVLISRSQDKLNQVSNNIKEKF-NVETRTIAVDFSLDD--IYDKIKTGLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVLSVCKVTRLVLPGMVE---------RSKGVILNISS--ASGMLPVPLLTIYSATKAFVDFFSQCLHEEYKSKGIFVQSVMPYLVATKLAKIQKPTLDKPSAETFVKSAIKTVG-------LQTRTTGYVIHSLMGSINSIMP---RWMYFKIIMGFSKSLRNRYLKKRKKN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P7R8-1", "uniprot_id": "DHB12_RAT", "id": "Q6P7R8-1", "name": "Very-long-chain 3-oxoacyl-CoA reductase", "aln": "-------MERALPAAG------FLYWVGASTIAYLTLRASYSLFRAFQVWCVGNQAFVGPRLGEWAVVTGGTDGIGKSYAEELAKRGMKIVLISRSQDKLKEVSNNIKEKF-NVETRTIAVDFSLDD--IYDKIKTGLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVLSICKVTRLVLPGMVE---------RSKGVILNISS--ASGMLPVPLLTVYSATKAFVDFFSQCLHEEYKSKGIFVQSVLPFFVATKLAKIRKPTLDKPSAETFVKSAIKTVG-------LQTRTTGYVIHAIMGSINSILP---RWIYFKTIMGFNKSLRNRYLKKTKKN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3HWX8-1", "uniprot_id": "G3HWX8_CRIGR", "id": "G3HWX8-1", "name": "Very-long-chain 3-oxoacyl-CoA reductase", "aln": "-------MESALPAAG------FLYWVGASTVAYLTLRVSYSLFRAFQVWCLGNESWVGPLLGEWAVVTGGTDGIGKSYAEELAKRGMKIVLISRSQDKLDQVSSEIKEKF-KVETRTIAVDFTLDD--IYDKIKTGLAGLEIGVLVNNVGMSYEYPEYFLEVPDLDNTIKKLININVLSVCKVTRLVLPGMVE---------RSKGVIVNISS--ATGMLPIPLLTIYSATKAFVDFFSQCLHEEYKSKGIFVQSVLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVG-------LQSRTTGYVIHALMGSINSILP---RWIYFKITMGFNKSLRNHYLKKNKKN----", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q53GQ0-1", "uniprot_id": "DHB12_HUMAN", "id": "Q53GQ0-1", "name": "Very-long-chain 3-oxoacyl-CoA reductase", "aln": "-------MESALPAAG------FLYWVGAGTVAYLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKF-KVETRTIAVDFASED--IYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVE---------RSKGAILNISS--GSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVG-------LQSRTNGYLIHALMGSIISNLP---SWIYLKIVMNMNKSTRAHYLKKTKKN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q869Y3-1", "uniprot_id": "Q869Y3_DICDI", "id": "Q869Y3-1", "name": "", "aln": "-------MSFTTVIQS------VALSIGLGILLRYAARFVLFLYAYFVRSPININ-----KYGSWVVVTGATDGIGKAYCHEFAKKKLNVVLVSRSLDKLKEVASEIENKF-KVQTKVISFDFNTTDDSKYQELFKQLSGIDIGVLVNNVGISYDHPMYLEELQPAS--IESLINLNVRAATVLSKFILTSMVE---------KKRGAIINLAS--VSGITPIPLLTVYSGTKAYIEKFSLALNLEYASKGIFVQCVTPGIVCSKMSKVRKSSLFVPQPSSFARSAIATIG-------YDRLTTGYWSHEIQAFFLRSLP---SFVVDKVMFDMHLGQRKRALNKKKSQ----", "tax_id": 44689, "tax_name": "Social amoeba" }, { "uniprot_ac": "Q8L9C4-1", "uniprot_id": "KCR1_ARATH", "id": "Q8L9C4-1", "name": "Very-long-chain 3-oxoacyl-CoA reductase 1", "aln": "-------MEICTYFKSQPTWLLILFVLGSISIFKFIFTLLRSFYIYFLRPSKNLR-----RYGSWAIITGPTDGIGKAFAFQLAQKGLNLILVARNPDKLKDVSDSIRSKYSQTQILTVVMDFSGDIDEGVKRIKESIEGLDVGILINNAGMSYPYAKYFHEVDEEL--INNLIKINVEGTTKVTQAVLPNMLK---------RKKGAIINMGSGAAALIPSYPFYSVYAGAKTYVDQFTKCLHVEYKKSGIDVQCQVPLYVATKMTKIRRASFLVASPEGYAKAALRFVG-------YEAQCTPYWPHALMGAVVSALP---ESVFESFNIKRCLQIRKKGLQKDSMKKE--", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "P38286-1", "uniprot_id": "MKAR_YEAST", "id": "P38286-1", "name": "Very-long-chain 3-oxoacyl-CoA reductase", "aln": "MTFMQQLQEAGERFRCINGLLWVVFGLGVLKCTTLSLRFLALIFDLFLLPAVNFDKYG-AKTGKYCAITGASDGIGKEFARQMAKRGFNLVLISRTQSKLEALQKELEDQH-HVVVKILAIDIAEDKESNYESIKELCAQLPITVLVNNVGQSHSIPVPFLETEEKE--LRNIITINNTATLLITQIIAPKIVETVKAENKKSGTRGLILTMGS--FGGLIPTPLLATYSGSKSFLQGWSNSLAGELSKDAIDVELIISYLVTSSMSKIRRSSLMIPNPQQFVKSTLRSVGRRCGSQERYATMTPYWAHAVYQFVITETFGVYSKIVNSINYSFHKSIRIRALKKAARQVKKE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :* :: : . *.: :** :***** :. ::*:: ::::*::*. .**. : ..:..:. :. : .*: . : : : :*:**.* *: . : : :..:*.:* . ::: : . ::: .:* *:.:.* : . *: : *:.:*:::: :: .* * ...: *: . * :.::*:::.:: .... :.:::: :* . * * : . : . * : *:* : ", "identical_positions": 39, "similar_positions": 120, "identity": "11.05%" }, { "cls_id": "homologset.oma.827485", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "I3LHC8-1", "uniprot_id": "I3LHC8_PIG", "id": "I3LHC8-1", "name": "Dehydrogenase/reductase SDR family member 6", "aln": "--------------------------------MGRLDGKVIILTAAAQGIGRAAALAFAREGAKVIATDINESKLQELEN--YPG-----IQTRVLDVTKKKQIDEFANDIER----LDVLFNVAGFVHHG--TILDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSIKGVVNRCVYSATKAAVIGLT-------KSVAADFIQQGIRCNCVCPGTVDTPSLQER-IQARPNPEEALSDF-----LKRQKTGRFATAEEVALLCVYLASDESAYVTGNPVVIDGGWSL---------------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "F1MLA4-1", "uniprot_id": "F1MLA4_BOVIN", "id": "F1MLA4-1", "name": "Dehydrogenase/reductase SDR family member 6", "aln": "--------------------------------MGRLDGKVIVLTAAAQGIGRAAALAFAKEGAKVIATDINDSKLQELDK--YPG-----IHTRVLDVTKKKQIDQFANDIER----LDVLFNVAGFVHHG--TILDCEETDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSIKGVVNRCVYSTTKAAVIGLT-------KSVAADFIQQGIRCNCVCPGTVDTPSLQER-IQARPNPEEALSDF-----LKRQKTGRFATAEEVALLCVYLASDESAYITGNPVIIDGGWSL---------------", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q9BUT1-1", "uniprot_id": "DHRS6_HUMAN", "id": "Q9BUT1-1", "name": "Dehydrogenase/reductase SDR family member 6", "aln": "--------------------------------MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK--YPG-----IQTRVLDVTKKKQIDQFANEVER----LDVLFNVAGFVHHG--TVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLT-------KSVAADFIQQGIRCNCVCPGTVDTPSLQER-IQARGNPEEARNDF-----LKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JZV9-1", "uniprot_id": "DHRS6_MOUSE", "id": "Q8JZV9-1", "name": "Dehydrogenase/reductase SDR family member 6", "aln": "--------------------------------MGRLDGKVIVLTAAAQGIGRASALAFAREGAKVIATDINESKLQELES--YRG-----IQTRVLDVTKKRQIDQFASEIER----IDVLFNVAGFVHHG--TILDCEEKDWDFSMNLNVRSMFLMIKAFLPKMLAQKSGNIINMSSVASSIKGVENRCVYSATKAAVIGLT-------KSVAADFIQQGIRCNCVCPGTVDTPSLQER-IQARDNPKEALKTF-----LNRQKTGRFASAEEVALLCVYLASDESAYVTGNPVIIDGGWSL---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A1J4-1", "uniprot_id": "DHRS6_RAT", "id": "D4A1J4-1", "name": "Dehydrogenase/reductase SDR family member 6", "aln": "--------------------------------MGRLEGKVIVLTAAAQGIGRASALAFAREGAKVIATDINEAKLQELEN--YPG-----IQTRVLDVTKKRQIDQFASEIEK----IDVLFNVAGFVHHG--TILDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSIKGVENRCVYSATKAAVIGLT-------KSVAADFIQQGIRCNCVCPGTVDTPSLQER-IQARDDPKEALKAF-----LNRQKTGRFASAEEVALLCVYLASDESAYVTGTPVVIDGGWSL---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1NAM7-1", "uniprot_id": "F1NAM7_CHICK", "id": "F1NAM7-1", "name": "Dehydrogenase/reductase SDR family member 6", "aln": "--------------------------------MGRLDGKVILLSAAAQGIGRATAIAFAKEGAKVIATDINKTKLQELEI--YPG-----IQVRVLDVTKREQIEELAKEIER----IDVLCNIAGFVHHG--TILDCEEEDWNFAMNLNVRSMYLMIKTFLPKMIKQKSGNIINMSSVASSIKGVVNRCVYSTSKAAVIGLT-------KSVAADFIEQGIRCNCVCPGTVDTPSLQQR-IKAQPNPDQALKDF-----LARQRIGRMATAEEVAHLFVYLASEESAYMTGNEVVIDGGWSL---------------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q54PL1-1", "uniprot_id": "Q54PL1_DICDI", "id": "Q54PL1-1", "name": "", "aln": "---------MFSSFKKIQNIGSTSIRFYSTIKKGRLDGKVALITGAADGVGRESSLLFAKEGAKVLLVDVNDIKGKEVES--LIKSSGGEASFFRADVSKASDVKEMIDAVEKTFGKLNILFNNAGIMISEDDDSVNTTEEVWDKTMNVNLKGVFLGCKFGIPALLRAGGGTIINTASFVAIMGAATPQIAYTASKGGVLAMT-------RELAIIHARQNIRVNALCPGPLRTELLDKF-LNTP----EKRNRR-----LVHLPMGRFGLANEIANGALFLASDESSYVTASTFLVDGGLTASYVTPL---------", "tax_id": 44689, "tax_name": "Social amoeba" }, { "uniprot_ac": "Q9C826-1", "uniprot_id": "ABA2_ARATH", "id": "Q9C826-1", "name": "Xanthoxin dehydrogenase", "aln": "------------------MSTNTESSSYSSLPSQRLLGKVALITGGATGIGESIVRLFHKHGAKVCIVDLQDDLGGEVCKSLLRGESKETAFFIHGDVRVEDDISNAVDFAVKNFGTLDILINNAGLCGAPCPDIRNYSLSEFEMTFDVNVKGAFLSMKHAARVMIPEKKGSIVSLCSVGGVVGGVG-PHSYVGSKHAVLGLT-------RSVAAELGQHGIRVNCVSPYAVATKLALAH-LPEEERTEDAFVGFRNFAAANANLKGVELTVDDVANAVLFLASDDSRYISGDNLMIDGGFTCTNHSFKVFR------", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q07530-1", "uniprot_id": "YD114_YEAST", "id": "Q07530-1", "name": "Uncharacterized oxidoreductase YDL114W", "aln": "MVRKNKINRASGTTKHLKDFPSVILSLPSYNPSILSKNATALITGGSSGLGFELAKELSRRINKVIVADIQS--FPTFAQVEYNN-----IFYYQCDITSLDEIKNLKKAIERDHGNINIIINNAGVAHIK--KLEHMTNKEVEQLIDINLIGAYRIISTFAEDMIDNREGFIINIASVLGELTPAR-LTSYGASKGAMIGFHKCMSRHFRSLSTECNKTGIKTLLVCPGKIKTNMFIDVPTPSKLLAPDIIPSQLALAIISAMEHNHLQTLNAPYYVNLVPFFKTLSWPYRHLLKHFSGMDHVTSTSPRAINPKRSA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :::..: *:* : :. ** .*::. . *: ::.: . : :::: * **. . : :::*: . : . :: * *:. .*. . : . * :* .::.: :.:: . .*: :.* : * : . : : . : . .* ", "identical_positions": 19, "similar_positions": 71, "identity": "5.97%" }, { "cls_id": "homologset.oma.827486", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6GV12-1", "uniprot_id": "KDSR_MOUSE", "id": "Q6GV12-1", "name": "3-ketodihydrosphingosine reductase", "aln": "---MLLLAAAGLVAFVLLLYMVS--PLISPKPLALPG--AHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKDIEKHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGTSMSGKFEELEVSSFEKLMSINYLGSVYPSRAVITTMKERRVG---RIVFVSSQAGQLGLFGFTAYSSSKFAIRGLAEALQMEVKPYNVYVTVAYPPDTDTPGLAEENKTKPLETRLISETTAICKPEQVAKQIVKDAIQGNFNSSIGSDGYMLSSLTCGMAPVTSITEGLQQVVTMGLFRTIALFYLGSFDNIVRRCMVQKAKPEVVDKTA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3HD45-1", "uniprot_id": "G3HD45_CRIGR", "id": "G3HD45-1", "name": "3-ketodihydrosphingosine reductase", "aln": "---MLLLAAAGLVAFVLLLYMVS--PLISPKPLALPG--AHVVVTGGSSGIGKCVAIECFKQGAFITLVARNEDKLLQAKKEIEKHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGTSLSGKFEELEVSAFEKLMSINYLGSVYPSRAVITTMKERRVG---RIVFVSSQAGQLGLFGFTAYSSSKFAIRGLAEALQMEVKPYNVYVTVAYPPDTDTPGLAKENKTKPLETRLISETTSICKPEQVAKQIVKDAIQGNFNSSIGSDGYMLSSLTCGMAPVTSITEGLQQVVTMGLFRIIALFYLGSFDNIVRRCMVKKAKPETVDKTA-", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q2KIJ5-1", "uniprot_id": "KDSR_BOVIN", "id": "Q2KIJ5-1", "name": "3-ketodihydrosphingosine reductase", "aln": "---MLLLAAASLVAFVLLLYMVS--PLISPKPLALPG--AHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEKHSINDKQVVLCISVDVSQDYSQVENVIKQAQEKLGPVDMLVNCAGMSLSGKFEDLEVSTFERLMSINYLGSVYPSRAVIATMKERRMG---RVVFVSSQAGQLGLFGYTAYSSSKFALRGLAEALQMEVKPYNVYVTVAYPPDTDTPGFAKENQTKPLETRLISETTSVCKPEQVAKQIVKDAVQGNFNSSIGSDGYMLSSLTCGMAPVTSIMEGLQQVVTMGLFRTIALFYLGSFDSIVRRCMMQKAKLETVDKTA-", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q06136-1", "uniprot_id": "KDSR_HUMAN", "id": "Q06136-1", "name": "3-ketodihydrosphingosine reductase", "aln": "---MLLLAAAFLVAFVLLLYMVS--PLISPKPLALPG--AHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVG---RIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRLISETTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTMGLFRTIALFYLGSFDSIVRRCMMQREKSENADKTA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1SMW5-1", "uniprot_id": "F1SMW5_PIG", "id": "F1SMW5-1", "name": "3-ketodihydrosphingosine reductase", "aln": "---MLLLAAAFLVAFVLLLYMVS--PLISPKPLALPG--AHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEKHSINDKQVVLCISVDVSQDYSQVENVIKQAQEKLGPVDMLVNCAGMSLSGKFEDLEVSTFERLMSVNYLGSVYPSRAVITTMKERRVG---RIVFVSSQAGQLGLFGFTAYSSSKFAIRGLAEALQMEVKPYNVYVTVAYPPDTDTPGFAEENKTKPLETRLISETTSVCKPEQVAKQIVKDAIQGNFNSSIGSDGYMLSSLTCGMAPVTSITEGLQQVVTMGLFRTIALFYLGSFDSIVRRCMMQRARSEIADKTA-", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A8V0YJG4-1", "uniprot_id": "A0A8V0YJG4_CHICK", "id": "A0A8V0YJG4-1", "name": "3-dehydrosphinganine reductase", "aln": "---MLLLAAAFIVAIVLLLYMVS--PLISPKPLKLPG--AHVVVTGGSSGIGKCIAIECYKQGAFITLIARDENKLLQTKKEIEKYSVNDKQVVLCISVDVSKDYEQVENVLKQAQEKLGPVDLLVNCAGTSVTGKFEDIEVNSFERLMAVNYLGSVYPSRAVISTMKERRMG---RIVFVSSQAGQLGLFGYTAYSPTKFALRGLAEALQMEVKPYNIYVTVAYPPDTDTPGFAEESKTKPLETKLISETSSVCQAEQVARVIVKDAIQGNFNSSVGSDGYMLSILTSGMSPVTSITEGLQQVVCMGIFRIVGLFYLGSFDSIVRRCMMQREKSENTDKTE-", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9VBU5-1", "uniprot_id": "Q9VBU5_DROME", "id": "Q9VBU5-1", "name": "3-dehydrosphinganine reductase", "aln": "--MELSWEIVFCVGIAVLVHVLVYVFVMAKKPRSIVG--RHVVVTGGSKGIGLCLAVECAMKGANVTVIARDEKMLSGAVALMEVIRQRPDQKFQYRSLDISGDYDQVAKVLGEIEDSFGPIYTLINCAGMAICGVFEEVSVQDVHKLMNVNFFGTYNCTRYVLPKMKKAGDG---IIVITASQAAMFGIYGYGPYSATKYALRAMAETIAMESREHGVSVTLAMPCDTNTPGFEEEEKSKPRETKIISGGGGLIEPEVMAKAILKDALKGKFTSTVGAESWLITTLGGALLPWDGFFTNLLHAIVLGPLRIVSYALHKYFNSVIRKCAREDKAKATSQVESK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0WRJ2-1", "uniprot_id": "KDSRA_ARATH", "id": "Q0WRJ2-1", "name": "3-dehydrosphinganine reductase TSC10A", "aln": "MAAISPLFLLFLIPIIPLSLLAILALIVRPRPIKIPIKSRHAFITGGSSGIGLALAHRAASEGARVSILARSGSKLEEAKKSIQLATG---VEVATFSADVR-DYDAVSKAIDES----GPIDVLIVNQGVFTAKELVKHSPEDVKFTIDVNLVGSFNVIKAALPAMKARKDRGPASISLVSSQAGQVGVYGYAAYSASKFGLQGLAQALQQEVISDDIHVTLIFPPDTNTPGFEEEQKSRPEVTAIIAASSGSMETEEVAKKAMDGIKAGNFTVSCNFEGFLLSLATTGMSPQRSFWLAFLEVITAGPIRLIALFFQWDWYKAIEKWSKTKTK---------", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * : :: :* : *..:****.*** .:* .. :** ::::**. . * : :: . * *: **. * :.: : **: *: * : . . . .. : :* .*: : .:. ** : :.:***. .*::*: .**.:*:.::.:*::: * .: :*: * **:***: :*.:::* * :*: . :.* :*: :.. *:*. : . :.:::: .: * .: : ..: * :* :. : . :.: ", "identical_positions": 57, "similar_positions": 116, "identity": "16.62%" }, { "cls_id": "homologset.oma.827487", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BTZ2-1", "uniprot_id": "DHRS4_HUMAN", "id": "Q9BTZ2-1", "name": "Dehydrogenase/reductase SDR family member 4", "aln": "-----------MHKAGL-LGLCARAWNS-----------------------VRMASSGMTRRD----PLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PKH6-1", "uniprot_id": "DR4L2_HUMAN", "id": "Q6PKH6-1", "name": "Dehydrogenase/reductase SDR family member 4-like 2", "aln": "-----------MQMARL-LGLCAWARKS-----------------------VRMASSRMTRRD----PLTNKVALVTASTDGIGFAIARRLAQDRAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLNNTLAIELAPRNIRVNCLHLDLSRLASAGCSGWTRKKRKA----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1MZD5-1", "uniprot_id": "F1MZD5_BOVIN", "id": "F1MZD5-1", "name": "", "aln": "-----------MLKVGLPLGACARSWKS-----------------------VRMASCGMARRN----PLENKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDRAVATLKGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGVDILISNAAVSPFFGSLMDVPEEVWDKILDVNVKATALLTKAVVPEMAKRGGGSIVIVSSIAAYSPFPSLGPYNVSKTALLGLTKNLALELAESNVRVNCLAPGLIRTSFSRVLWEDPARQESIKATFQIKRIGKPEECAGIVSFLCSEDASYITGETVVVAGGSLSHL", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q8WNV7-1", "uniprot_id": "DHRS4_PIG", "id": "Q8WNV7-1", "name": "Dehydrogenase/reductase SDR family member 4", "aln": "-----------MRAAGQLLRACSQTWKS-----------------------VRMASTGVERRK----PLENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTVCHVGKAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVLMTKAVVPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIRVNCLAPGLIKTNFSQVLWMDKARKEYMKESLRIRRLGNPEDCAGIVSFLCSEDASYITGETVVVGGGTASRL", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q8VID1-1", "uniprot_id": "DHRS4_RAT", "id": "Q8VID1-1", "name": "Dehydrogenase/reductase SDR family member 4", "aln": "-----------MQKAGLLLRGWTRAWKS-----------------------VRMASSGLTRQN----PLANKVALVTASTDGIGLAIARRLAEDGAHVVISSRKQQNVDRAVATLQGEGLSVTGVVCHVGKAEDREKLVNMALKLHQGIDILVSNAAVNPFFGNLMDVTEEVWNKVLSINVTASAMMIKAVVPAMEKRGGGSVVIVSSVAGFVLFPSLGPYNVSKTALLGLTKNFAAELAPKNIRVNCLAPGLIKTHFSSVLWKEKAREEMIKETMQIRRLGKPEDCVGIVSFLCSEDASYINGETVVVGGGTPSRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LB2-1", "uniprot_id": "DHRS4_MOUSE", "id": "Q99LB2-1", "name": "Dehydrogenase/reductase SDR family member 4", "aln": "-----------MQKAGRLLGGWTQAWMS-----------------------VRMASSGLTRRN----PLSNKVALVTASTDGIGFAIARRLAEDGAHVVVSSRKQQNVDRAVATLQGEGLSVTGIVCHVGKAEDREKLITTALKRHQGIDILVSNAAVNPFFGNLMDVTEEVWDKVLSINVTATAMMIKAVVPEMEKRGGGSVVIVGSVAGFTRFPSLGPYNVSKTALLGLTKNFAAELAPKNIRVNCLAPGLIKTRFSSVLWEEKAREDFIKEAMQIRRLGKPEDCAGIVSFLCSEDASYINGETVVVGGGTPSRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1Q8N0-1", "uniprot_id": "F1Q8N0_DANRE", "id": "F1Q8N0-1", "name": "", "aln": "-----------MLKAIT-RCLWSNPVAG-----------------------RRMMSHHISQN------LSGKVAIVTASTDGIGLAAAEALGQRGAHVVVSSRRQTNVDKAVSLLRSKNIKVIGTTCNVGKAEDREKLINMTVEQCGGVDILVSNAAVNPFFGNILDSTEEVWDKILGVNVKASFLLTKMVVPHIEKRGGGSVVIVSSVAGYQPMPALGPYSVSKTALLGLTRALAPELAQSNIRVNCVAPGIIKTRFSSALWENEGVLEEFLKQTSIKRLGQPEEIGGVIAFLCSDEASYITGETITVTGGMNSRL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRJ4-1", "uniprot_id": "Q9VRJ4_DROME", "id": "Q9VRJ4-1", "name": "", "aln": "MLHLSKQLVVRAPKIRLNASAVSGSGQSSSFDQNSNNYSRKLVGPNLNQCHKRLSSSSQSSTAGTMKRLAGKVAVVTASTDGIGFAIAKRLAEDGAAVVISSRKQKNVDSALAELRKLNLNVHGLKCHVSEPEDRKQLFEETISKFGKLNILVSNAATNPAVGGVLECDEKVWDKIFDVNVKSSYLLAKEALPLLRQQKNSSIVFVSSIAGYDAFELLGAYSVSKTALIGLTKAAAKDLAPEGIRVNCLAPGVIRTKFSKALYENESANEAALSKIPMGRLGTSEEMAGVVSFLVSEDAGYITGESIVAGGGMTARL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9S9W2-1", "uniprot_id": "SDRA_ARATH", "id": "Q9S9W2-1", "name": "Short-chain dehydrogenase/reductase SDRA", "aln": "------------------------------------------------------MEKKLPRR------LEGKVAIVTASTQGIGFGITERFGLEGASVVVSSRKQANVDEAVAKLKSKGIDAYGIVCHVSNAQHRRNLVEKTVQKYGKIDIVVCNAAANPSTDPILSSKEAVLDKLWEINVKSSILLLQDMAPHLEK--GSSVIFITSIAGFSPQGAMAMYGVTKTALLGLTKALAAEMAP-DTRVNAVAPGFVPTHFASFITGSSEVREGIEEKTLLNRLGTTGDMAAAAAFLASDDSSYITGETLVVAGGMPSRL", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * .***:*****:***:. :. :. * **:***:* *** ::: *: .:.. * *:*.:.:.*..*. ::. ::*::.***..* . ::. * * :* :**.:. :: : * : : ..*:::: *:..: :. *.*:****:**.. * ::* . ***.: .. : . ", "identical_positions": 54, "similar_positions": 79, "identity": "17.03%" }, { "cls_id": "homologset.oma.827488", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q91VT4-1", "uniprot_id": "CBR4_MOUSE", "id": "Q91VT4-1", "name": "3-oxoacyl-[acyl-carrier-protein] reductase", "aln": "MDKVCAVFGGSRGIGRAVAQLMAQKGYRLAIVSRNLEVAKVTAGELGG-NHLAFRCDVAKEQDVQSTFQEMEKHLGPVNFLVNAAGINRDSLLVRTKTEDMISQLHTNLLGSMLTCKAAMKTMIQQ-GGSIVNVGSIIGLKGNVGQSAYSATKGGLVGFSRSLAKEVARKKIRVNVVAPGFIRTDMTRHLKEEHFKKNIPLGRFGETLEVAHAVVFLLESPYITGHVLIVDGGLQLTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TS56-1", "uniprot_id": "CBR4_RAT", "id": "Q7TS56-1", "name": "3-oxoacyl-[acyl-carrier-protein] reductase", "aln": "MDKVCAVFGGSRGIGKAVAQLMAQKGYRLAIVARNLEVAKATASELGG-IHLAFRCNIAKEGDVHSTFEEMEKHLGPVNFLVNAAGINRDSLLVRTKTEDMLSQLHTNLLGTMLTCRAAMRTMIQQ-GGSIVNVGSIIGLKGNVGQAAYSATKGGLIGFSRSLAKEVARKKIRVNVVAPGFIHTDMTKHLKEEHFKKNIPLGRFGEALEVAHAVVFLLESPYITGHVLIVDGGLQLTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3H3B9-1", "uniprot_id": "G3H3B9_CRIGR", "id": "G3H3B9-1", "name": "3-oxoacyl-[acyl-carrier-protein] reductase", "aln": "MDKVGAVFGGSRGIGRAVAQLMAQKGYRLAIVARNLQVAKAAAGELGG-NHLAFSCDVAKEQDVQNTFEEMEKHLGPVNFLVNAAGINRDGLLVRTKTEDMISQLHTNLLGSMLTCKAAMRTMIQR-GGSIVNVGSIIGLKGNVGQSVYCASKGGLIGFSRSLAKEVARKKIRVNVVAPGFIHTDMTKHLKEEHLKKNIPLGRFGEALEVAHAVVFLLESPYVTGHVLVVDGGLQLTI", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q8N4T8-1", "uniprot_id": "CBR4_HUMAN", "id": "Q8N4T8-1", "name": "3-oxoacyl-[acyl-carrier-protein] reductase", "aln": "MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGG-DHLAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLESPYITGHVLVVDGGLQLIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RIX8-1", "uniprot_id": "F1RIX8_PIG", "id": "F1RIX8-1", "name": "3-oxoacyl-[acyl-carrier-protein] reductase", "aln": "MDRVCAVFGGSRGIGRAVARLMAQRGYRLAIVARNLQGARAVAGDLGG-DHLALSCDVAKEQDVQSTFEEIEKNLGPVNFLVNAAGINRDNLLVRTSTEDMLCQLQTNLLGSMLTCKAAVKTMIKQQGGSIVNIGSVVGLKGNPGQSVYSASKGGLVGFSRALAKEVAKKKIRVNVVAPGFVHTDMTKDLKEEHLKSNIPLGRFGDPLDVAHAVLFLLESPYITGHALVVDGGLQLTM", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A4IFA7-1", "uniprot_id": "CBR4_BOVIN", "id": "A4IFA7-1", "name": "3-oxoacyl-[acyl-carrier-protein] reductase", "aln": "MDKVCAVFGGSRGIGRAVARLMAQRGYRLAIVARNLEGARAAAGDLGG-DHLALSCDVAKEHDVQNTFEEIEKNLGRVNFLVNAAGINRDNLLVRTNTEDMLSQLHTNLLGSMLTCRAALKTMIKQQRGSIVNVGSVVGLKGNSGQSVYSASKGGLVGFSRALAKEVAKKKIRVNVVAPGFIHTDMTKDLNEELLKKNIPLGRFGDALDVAQAAVFLLESPYVTGHVLVVDGGLQLTM", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A8V0XXB7-1", "uniprot_id": "A0A8V0XXB7_CHICK", "id": "A0A8V0XXB7-1", "name": "3-ketoacyl-[acyl-carrier-protein] reductase beta subunit", "aln": "MGKICAVFGGSRGIGKAVAELLARKGCHLAIIARNLEVAQNTARSLGA-GHLALSCDVSREQEVQHAFEEIQRNLGPINYLVNAAGINRDGLLLRTKTEDIVSQIHTNLLGTMLTCKAAVKSMIHHQGGAIVNIGSVVGLKGNSGQSIYSASKAGIVGFSRSLAKEVARKQIRVNVVAPGFIHTEMTAHLEEDELKKAIPLGRFGDPHEVAQAVLFLLESPYVTGSTLIVDGGLQLLI", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q6P0H7-1", "uniprot_id": "CBR4_DANRE", "id": "Q6P0H7-1", "name": "Carbonyl reductase family member 4", "aln": "MSRLAVVFGGSRGIGRAASKLLAQRGHRIVLLSRNKEAAQSTAQSLPGENHLGLSCDVSKEEEVQKAFETINKTCGTVGFLVNAAGINRDALLLRSKSEDMLSVLHTNLLGSMLTCKAAVRNMLSH-GGAIVNIGSVVGVKGNAGQCVYSASKAGLEGFTRSLAKEVASRNIRVNLVAPGLIHTDMTAGLAEEAAVRTIPLGRFGEPAEVAQAMLFLLESPYITGQILLVDGGLQLLM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:: .*********:*.:.*:*::* ::.:::** : *: .* .* . **.: *::::* :*: :*: ::: * :.:********** **:*:.:**::. ::*****:****:**::.*: : *:***:**::*:*** **. *.*:*.*: **:*:****** ::****:****:::*:** * *: *******:. :**:* :*******:** *:******* ", "identical_positions": 118, "similar_positions": 81, "identity": "49.58%" }, { "cls_id": "homologset.oma.827489", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "E9Q3D4-1", "uniprot_id": "DHB14_MOUSE", "id": "E9Q3D4-1", "name": "L-fucose dehydrogenase", "aln": "--------------------------------MAAVTRYSGKVVVVTGGSRGIGAAIVRAFVDSGAQVVFCDK------DEAGGRALEQELSGT----------------VFIPGDVTQERDLQTLVSETLSRFGHLDCVVNNAGYHPPAQLPEETSAQGFRQLLEVNLLGTYTLIKLALPHLRKSRGNIINISSLVGAIGQSQALTYVATKGAVTAMTKALALDESRHGVRVNCISPGNIWTPLWEELAASTSDPRATILEGTLAQPLGRMGQPAEVAAAAVFLAS--EATFCTGLELLVTGGAELGYGRKASKSSLGEVPTLPPNVH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GJ95-1", "uniprot_id": "DHB14_RAT", "id": "A0A8I6GJ95-1", "name": "L-fucose dehydrogenase", "aln": "--------------------------------MAAVGRYSGKVVVVTGGSRGIGAAIVRAFVDSGAQVVFCDK------DEAGGRAVEQELLGT----------------VFIPGDVTQEGDLQTLISETVSRFGHLDCVVNNAGYHPPAQLPEETSAQGFRQLLEENLLGAYTLIKLALPHLRKSKGNIINISSLVGAIGQSQALTYVATKGAVTAMTKALALDESRYGVRVNCISPGNIWTPLWQELAAATSDPRATILEGTLAQPLGRMGQPAEVGAAAVFLAS--EATFCTGLELFMTGGAELGYGRKASSSTLVEVPILPP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BPX1-1", "uniprot_id": "DHB14_HUMAN", "id": "Q9BPX1-1", "name": "L-fucose dehydrogenase", "aln": "--------------------------------MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDK------DESGGRALEQELPGA----------------VFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS--EANFCTGIELLVTGGAELGYGCKASRSTPVDAPDIPS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9MYP6-1", "uniprot_id": "DHB14_BOVIN", "id": "Q9MYP6-1", "name": "L-fucose dehydrogenase", "aln": "--------------------------------MAMGTRYAGKVVIVTGGGRGIGAGIVRAFVESGAQVVICDK------DEARGRAVERELPGT----------------VFLLCDVTREEDVRTLVSETIRRFGRLDCIVNNAGYHPPPQWPEETSAQGFRQLLELNLLGTYTLTKLALPHLRKSRGNVINISSLVGAIGQSQAVPYVATKGAVTAMTKALALDESQYGVRVNCISPGNIWTPLWEELAASTPDPTATIREGTLAQPLGRMGQPAEVAAAAVFLAS--EATFCTGTELLVTGGAELGYGRKAGQAAPAEAPTTPS---", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q9FZ42-1", "uniprot_id": "ADRC1_ARATH", "id": "Q9FZ42-1", "name": "NADPH-dependent aldehyde reductase 1, chloroplastic", "aln": "MASEK----QKQHAQPGKEHVMESSPQFSSSDYQPSNKLRGKVALITGGDSGIGRAVGYCFASEGATVAFTYVKGQEEKDAQETLQMLKEVKTSDSKEP-----------IAIPTDLGFDENCKRVVDEVVNAFGRIDVLINNAAEQYESSTIEEIDEPRLERVFRTNIFSYFFLTRHALKHMKEG-SSIINTTSVNAYKGNASLLDYTATKGAIVAFTRGLALQLAEKGIRVNGVAPG----PIWTPL-IPASFNEEKIKNFGSEVPMKRAGQPIEVAPSYVFLACNHCSSYFTGQVLHPNGGAVVNA--------------------", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q75JT8-1", "uniprot_id": "Q75JT8_DICDI", "id": "Q75JT8-1", "name": "", "aln": "METKEGTFQKQQQDVPGVQSEMNPVPDCGEETYKGNNRLRGRRVLVTGGDSGIGRAVTIAMFREGADVCISYLPSEKKDADSLKCLLEKEIKNTSGGGSGGGTTTCGGKFEMIQGDLTCEKFCKDLVEETKNRLGGLDTLVLVAGKQCAKNCITEITTEQLMETFQVNVFSMFHIVKAALPHLSKG-STITTTTSIEAFSGSPFLLDYATSKGAIVSFTQSLSKQVAHRGIRVNSVAPG----PVWTPIEISGGYPQDKLSTFGKNTPMGRAGQPSEVAPMYVFLAS-CDSTYCTGDIFPVTGGKHL----------------------", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: .::***. *** .: .: .** * : : :*: : : *: : : ::.*. :* :* :: *. : . * : . :. *::. : : : ** :: :. ..: . :*: . *.. : *.::***:.::*:.*: : : *:*** ::** *:* : .: *: * *** **.. ****. :.: ** : .** : ", "identical_positions": 51, "similar_positions": 84, "identity": "15.5%" }, { "cls_id": "homologset.oma.827490", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q91X52-1", "uniprot_id": "DCXR_MOUSE", "id": "Q91X52-1", "name": "L-xylulose reductase", "aln": "-------MDLGLAGRRALVTGAGKG---IGRSTVLALKAAGAQVVAVSRTREDLDDLVRECPGVEPVCVDLADWEATEQALSNVGPVDLLVNNAAVALLQPFLEVTKEACDTSFNVNLRAVIQVSQIVAKGMIARGVPGAIVNVSSQASQRALTNHTVYCSTKGALDMLTKMMALELGPHKIRVNAVNPTVVMTPMGRTNWSDPHKAKAMLDRIPLGKFAEVENVVDTILFLLSNRSGMTTGSTLPVDGGFLAT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3GXD0-1", "uniprot_id": "G3GXD0_CRIGR", "id": "G3GXD0-1", "name": "L-xylulose reductase", "aln": "-------MDLGLAGRRALVTGAGKG---IGRSTVLALQAAGARVVAVSRTQADLDSLASECPGVETVCVDLADWETTEKALSSVGPVDLLVNNAAVALLQPFLEVTKEACDTSFNVNLRAVIQVSQIVARGMIARGVPGAIVNVSSQASQRALTNHSVYCSTKGALDMLTKMMALELGPHKIRVNAVNPTVVMTPMGRTNWGDPHKAKVMLDRIPLGKFAEVENVVDAILFLLSNRSSLTTGCTLPVDGGFLAT", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "A0A286ZQ44-1", "uniprot_id": "A0A286ZQ44_PIG", "id": "A0A286ZQ44-1", "name": "L-xylulose reductase", "aln": "-------MELGLAGRRALVTGAGKG---IGRSTVQALHAAGAQVVAVSRTQADLDSLVRECPGVEPVCVDLGDWEATERALGGVGPVDLLVNNAAVALMQPFLEVTKEACDRSFEVNLRAVIQVSQIVARGLIARGAPGSIVNVSSQASQRALPNHSVYCSTKGALDMLTKMMALELGPHKIRVNAVNPTVVMTPMGRANWSNPPKAKAMLDRIPLGRFAEVEHVVDAILFLLSDRSSMTTGSTLPVDGGYLAT", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q7Z4W1-1", "uniprot_id": "DCXR_HUMAN", "id": "Q7Z4W1-1", "name": "L-xylulose reductase", "aln": "-------MELFLAGRRVLVTGAGKG---IGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGGFWAC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V1AB26-1", "uniprot_id": "A0A8V1AB26_CHICK", "id": "A0A8V1AB26-1", "name": "", "aln": "MWSCWSGVQRAIEMIRGLEHLSYKERPRIGRAVAVALCKAGARVTALSRTAADLESLVRECPGIEPLCLDLADWDATEAAVGAAGPFELLVNNAAVAMLQPFLQVTREAVKRSFDVNFRAVLHVSQIVARQMIAQGLPGAIVNVSSQASQRALRDHAVYCSTKSALDMLSKVMAMELGPHKIRVNTVNPTVVMTDMGRINWSDPQKSAAMINRIPLGKFAEVDDVVNSILFLLSDKSAMTTGSSLMVDGGFLVS", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : * * : * ***... ** :**:*.*:*** **:.*. ****:*.:*:**.**::** *:. .**.:*********::****:**:** . **:**:***::******: :**:* **:*******.****: :*:******.*****:*:**:**********:******** **: .*.:* *: .*::*****:****:.**::******::*.:***.:* *:**: . ", "identical_positions": 143, "similar_positions": 70, "identity": "56.3%" }, { "cls_id": "homologset.oma.827491", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A0T8-1", "uniprot_id": "D4A0T8_RAT", "id": "D4A0T8-1", "name": "", "aln": "MSWELLLWLLALCAVILPLVQFLRFLRADADLTLLWAEWQGRRPEWELTDMVVWITGASSGIGEELAFQLSKLGVCLVLSARRGQELERVKRRCLENGNLKEKDILVLPLDLTDTSSHEAATKAVLQEFGKIDILVNNGGRSQRSLVLETNLEVFKELMNLNYLGTVSLTKCVLPHMVERKQGKIVTVNSLAGIASVSLSSGYCASKHALRGFFNALHSELGKYPGITLCNVYPGPVQSNVVKNALTEELTKPMRENIDQSYKMPTSRCVRLMLISMANDLKEVWISDQPILLGAYIWQYMPTWALWLTCKLGEKRIQNFRNNLDPDSQ-YTLWKPKRD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CXR1-1", "uniprot_id": "DHRS7_MOUSE", "id": "Q9CXR1-1", "name": "Dehydrogenase/reductase SDR family member 7", "aln": "MSWELLLWLLALCALILPLVQLLRFLRADADLTLLWAEWQGRRPEWELTDMVVWVTGASSGIGEELAFQLSKLGVSLVLSARRAQELERVKRRCLENGNLKEKDILVLPLDLTDTSSHEAATKAVLQEFGKIDILVNNGGRSQRSLVLETNLDVFKELINLNYIGTVSLTKCVLPHMIERKQGKIVTVNSIAGIASVSLSSGYCASKHALRGFFNALHSELGQYPGITFCNVYPGPVQSDIVKNAFTEEVTKSMRNNIDQSYKMPTSRCVRLMLISMANDLKEVWISDHPVLLGAYIWQYMPTWAAWLNCKLGKERIQNFKNNLDPDLP-YKFLKAKKD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3IAP8-1", "uniprot_id": "G3IAP8_CRIGR", "id": "G3IAP8-1", "name": "", "aln": "MSWELLLWLLALCALILPLVQFLRFLRADADLTLLWAEWQGRRPEWELTDMVVWVTGASSGIGEELALQLSKLGVSLVLSARRVQELERVKRRCLETGNLKEKDILVLPLDLTDTDSHEAATKAVLQEFGKIDILVNNGGRSQRSLVLETNLDVFKELINLNYLGTVSLTKCVLPHMVERKQGKIVTVNSAAGIASVALSSGYCASKHALRGFFNALQCELIQYPGITFCNVYPGPVQSDIVKNALTEEVTKPMRNGIDQSYKMPTSRCVRLMLISMANDLKEVWISDHPVLMGTYMWQYMPTWALWLTSKLGKKRIQNFKNGLDPDTS-YNIWKTKRD", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q9Y394-1", "uniprot_id": "DHRS7_HUMAN", "id": "Q9Y394-1", "name": "Dehydrogenase/reductase SDR family member 7", "aln": "MNWELLLWLLVLCALLLLLVQLLRFLRADGDLTLLWAEWQGRRPEWELTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRIENFKSGVDADSSYFKIFKTKHD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1SSI2-1", "uniprot_id": "F1SSI2_PIG", "id": "F1SSI2-1", "name": "", "aln": "MSWELFLWLLALCVLLALVVQLLRFLRADGDLTLLWAEWQGRRPEWELTDMVVWVTGASSGIGEELVYQLSKLGVSLVLSARRVQELERVKRRCLENGILKGKDILILPLDLANRSSHEVATKAVLQEFGKIDILVNNGGVSQRSLCVDTSLDVYKELMEVNYLGTVSLTKCVLPHMIEKKQGKIITVNSFMGIIAAPLSGGYCASKHALRGFFNTLRTELATYPGITVSNVCPGPVKSNIVKNALTEEVTKTLGSDADQSHKMATSRCARLMLIAMANDLKEVWIAEQPFLSMAYLWQYIPTWAWWLTSKIGKKRIENFKSGVDADSSYFKIWKKKHD", "tax_id": 9823, "tax_name": "Pig" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.***:****.**.:: :**:*******.************************:***********. *******.******* :***********.* ** ****:*****:: .***.**********:********* ***** ::*.*:*:::*:::**:*************:*:*****:**** ** :..** ************** *: ** **** ..*: ****:*::*:*::: *:**.: .. ***:**.****.*****:**********:::*.* :*:***:**** *:. *:*::**:**:..:*.* :.: * *:*", "identical_positions": 229, "similar_positions": 79, "identity": "67.55%" }, { "cls_id": "homologset.oma.827493", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V8F9-1", "uniprot_id": "HSDL2_RAT", "id": "Q4V8F9-1", "name": "Hydroxysteroid dehydrogenase-like protein 2", "aln": "MLPNTGKLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTTQRHPKLLGTIYTAAEEIEAAGGKALPCVVDVRDEQQINSAVEKAVERFGGIDILVNNASAISLTNTLETPTKRVDLMMSVNTRGTYLTSKACIPFLKKSKVAHILNLSPPLNLNPMWFKQHCAYTIAKYGMSMCVLGMAEEFRG-EIAVNALWPRTAIHTAAMDMLGGAGVESQCRKVDIIADAAYSIFKR-PKSFTGNFIIDENILKEEGIKDFDIYAITPG--HPLLPDFFLDEHPDAVMEEKESYDPVPEVKEEKLQLQEQPQLQEQPQLQEKPQLQEQPQLQEKPQLQEQPQLQEQPQLQEQPQQQPQLQEQPQLQEKPQLQEQPQQQEKPQPQQQPQQQPQQRPQQRPQPQPQPQPLLQSVLPPKPHFGAVEETFRIVKDSLSDEVVRATQAVYQFELSGEDGGTWFLDLKSKGGKVGHGEPSDRADVVMSMATEDFVKMFSGKLKPTMAFMSGKLKIKGNIALAIKLEKLMTHMNSRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2TPA8-1", "uniprot_id": "HSDL2_MOUSE", "id": "Q2TPA8-1", "name": "Hydroxysteroid dehydrogenase-like protein 2", "aln": "MLPNTGKLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTTQKHPKLLGTIYTAAEEIEAAGGTALPCVVDVRDEQQINSAVEKAVEKFGGIDILVNNASAISLTNTLDTPTKRVDLMMNVNTRGTYLTSKACIPFLKKSKVGHILNLSPPLNLNPLWFKQHCAYTIAKYGMSMCVLGMAEEFRG-EIAVNALWPRTAIHTAAMDMLGGSGVENQCRKVDIIADAAYSIFKR-PKSFTGNFIIDENILKEEGIKNFDVYAIAPG--HPLLPDFFLDEHPDAVMEEKESNDSVPEVKEEKLQLQEESQLQKQPQLQEQPQLQEKPQLQEKPQLQEQPQLQEKPQLQEQPQQR----EQPQLQ------------------------------QQPRPRQQPQPFVQSMLPQKPHFGAVEETFRIVKDSLSDEVVRATQAVYQFELSGEDGGTWFLDLKSKGGKVGHGEPSDRADVVMSMATDDFVKMFSGKLKPTMAFMSGKLKIKGNIALAIKLEKLMTQMNSRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6YN16-1", "uniprot_id": "HSDL2_HUMAN", "id": "Q6YN16-1", "name": "Hydroxysteroid dehydrogenase-like protein 2", "aln": "MLPNTGRLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKALPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRGTYLASKACIPYLKKSKVAHILNISPPLNLNPVWFKQHCAYTIAKYGMSMYVLGMAEEFKG-EIAVNALWPKTAIHTAAMDMLGGPGIESQCRKVDIIADAAYSIFQK-PKSFTGNFVIDENILKEEGIENFDVYAIKPG--HPLQPDFFLDEYPEAVSKKVESTGAVPEFKEEKLQL----------------------------------------------------------------------------------------------------------QPKPRSGAVEETFRIVKDSLSDDVVKATQAIYLFELSGEDGGTWFLDLKSKGGNVGYGEPSDQADVVMSMTTDDFVKMFSGKLKPTMAFMSGKLKIKGNMALAIKLEKLMNQMNARL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A5G2R0Z8-1", "uniprot_id": "A0A5G2R0Z8_PIG", "id": "A0A5G2R0Z8-1", "name": "Hydroxysteroid dehydrogenase-like protein 2", "aln": "MLPNTGRLAGCTVFITGASRGIGKAIALKAAKDGANVVIAAKTTQTHPKLQGTIYTAAEEIQAAGGKALPCVVDVRDEQQISDAVEKAVEKFGGIDILVNNASAISLTNTLETPTKRVDLMMNVNTRGTYLTSKACIPYLKKSRIAHILNLSPPLNLNPLWFKQHCAYTIAKYGMSMCVLGMAEEFKG-EIAVNALWPKTAIHTAAMDMLGGSGIESQCRKVDIIADAAYCIFKK-PKSFTGNFIIDENILKEEGITNFDVYAVTPG--HPLLPDFFLDEQPETVIKKMESHGADPELKKEKLPP----------------------------------------------------------------------------------------------------------PPKPCSGAVEETFRIVKESLSDDVVKATQAIYQFELSGEDGGTWFLDLKSKGGNVGYGEPSDRADVVMSMSTDDFVKMFSGKLKPVVAFLSGKLKIKGNMALAIKLEKLMNQMNARL", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A4FUZ6-1", "uniprot_id": "HSDL2_BOVIN", "id": "A4FUZ6-1", "name": "Hydroxysteroid dehydrogenase-like protein 2", "aln": "MLPNTGKLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQAHPKLPGTIYTAAEEIKAAGGKALPCIVDVRDEEQISSAVEKAVEKFGGIDILVNNASAISLTNTLETPTKKVDLMMNVNTRGTYLTSKACIPYLKKSKVAHILNLSPPLNLNPLWFKQHCAYTIAKYGMSMCVLGMAEEFKG-EIAVNALWPRTAIHTAAMDMLGGSGVESQCRKVDIMADAAYCIFKK-PKSFTGNFIIDENILKEEGIKNFDVYAITPG--HPLLPDFFLDEQPAMVTKKADSYGAVPELKEEKTQP----------------------------------------------------------------------------------------------------------PPKARSGAVEETFRIVKDSLSDDIVKATQAVYQFELSGEDGGTWFLDLKSKGGNIGYGEPSDQADVVMSMSTDDFVKMFSGKLKPTMAFMSGKLKIKGNMALAIKLEKLMNQMNSKL", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "E1C7S2-1", "uniprot_id": "E1C7S2_CHICK", "id": "E1C7S2-1", "name": "Hydroxysteroid dehydrogenase-like protein 2", "aln": "MLPNTGKLAGCTLFITGASRGIGKAIALKAARDGANIVIAAKTAEPHPKLPGTIYTAAEEIEAAGGRALPCIVNVRQEEQIISAVEKAVKTFGGIDILVNNASAISLTGTLETETKKVNLMMDVNVRGTYLTSKACLPYLRKSKNPHILNLSPPMNMKPIWFKNHCAYTISKYGMSMCVLGMAEEFKG-EVAVNALWPKTAIHTAAMDMLGGSGIEKQCRKTDIIADAAYCILTK-PKSFTGNFIIDEVLLREEGVKDFDVYAIAPG--HPLMPDFFLD----AETDMTESHGASQASDGAKANK-----------------------------------------------------------------------------------------------------------ESAPAGPVAETFRLIQGELNKEMVKSTQGVFQFELSGDEGGTWYLDLKTSSGSAGFGKPPAAADVVMSMSSGDFVKMFTGKLKPTMAFMSGKLRIKGNMALAVKLEKMLTQFNAKL", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q6P5L8-1", "uniprot_id": "HSDL2_DANRE", "id": "Q6P5L8-1", "name": "Hydroxysteroid dehydrogenase-like protein 2", "aln": "MLQNTGKLAGCTIFITGASRGIGKAIALKAAQDGANVVIAAKTADPHPKLPGTIYTAAAEIEAAGGKALPCIVDVRDEKQINDAVEQAVEKFGGIDILVNNASAINLTGTLQTPMKKADLMLGINLRGTYLTSKLCIPHLLKSKNPHILNLSPPLNLNPIWFKNHTAYTIAKYGMSMCVLGMAEEFRG-SIAVNALWPKTAIQTAAMDMLGGSEVGKQCRKVEIMADAAYAIFKQ-PTSFTGQFVIDEDILKKEGIKDFDVYAVEPG--HPLLPDFFLDGQPEDLVKHMEAHGATPAFTTAKADP-------------------------------------------------------------------------------------------------------------VAAGPVSEMFNTIRGIISPEMVKTTQGVYKFNLAGEHAGVWYLDLKNDAGSAGNGEPPVKADVVMSMDSEDFVKMFGGKLKPTMAFMSGKLTIKGDMGLAIKLEKMMAMMKSKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q54DN0-1", "uniprot_id": "Q54DN0_DICDI", "id": "Q54DN0-1", "name": "Hydroxysteroid dehydrogenase-like protein 2", "aln": "------MLKGKTIFITGASRGIGEAIAIAAGKEGANVVIAAKTADPHPKLKGTIFSVQKAVEDAGGKCLACSVDIRFEDQIEDAVKKAVEKFGGIDILINNASAISLTGTLETNSKKFDLMMGVNTRGTYLTTQKCLPYLLKSKTAHVINLSPPLNMDKKWFANHPAYTMAKYGMSMCVLGMAEEFKG-KVAFNALWPKTAIYTAAMEMLGGSDVGKQCRTVDILSDSVMWILKQ-PITTTGNFFIDEYCVKQAGITDLEKYSIVKG--AKLMNDFFLED------DVDYSILPTPKL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 44689, "tax_name": "Social amoeba" }, { "uniprot_ac": "Q9VB10-1", "uniprot_id": "Q9VB10_DROME", "id": "Q9VB10-1", "name": "Hydroxysteroid dehydrogenase-like protein 2", "aln": "-MINTGKLAGRTLFITGASRGIGKEIALKAARDGANIVVAAKTAEPHPKLPGTIYSAAEEIEKAGGKAYPCVVDVRDEQQVRSAVEAAVAKFGGIDIVINNASAISLTNTPDTDMKRYDLMHNINTRGTFLVSKVCLPYLKKSNHAHILNISPPLSMKPKWFGPHVAYTMAKYGMSMCVLGMAAEFKDEGISVNALWPRTAIHTAAIEMLTGPDSAKWSRKPEIMADAAYAILTREPRQSTGQFFVDDEVLESAGITDLTEYACFRENADKLMVDFFVEEKGAPVENEAAAEDAAAPASGG-------------------------------------------------------------------------------------------------------------------DVKIPQLFRKIESLLSPEIVSKTQAVFQFNISGAEQGTWFLDLKNGSGSCGAGTPTAAPDATLTMNSKNFFDMFSGKLKAAPAYMTGKLKISGDFQKALKLEKLMKALKSKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * *:**********: **: *.::***:*:****:: **** ***::. :: .** . .* *::* *.*: **: *: ******::******.**.* :* *: :** .:* ***:*.:: *:*.* **. *::*:***:.:. ** * ***::****** ***** **:. ::.*****:*** ***::** *. . .*. :*::*:. *: : * **:*.:*: :.. *: :: *: * ***:: . : . ", "identical_positions": 123, "similar_positions": 84, "identity": "23.3%" }, { "cls_id": "homologset.oma.827494", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BY49-1", "uniprot_id": "PECR_HUMAN", "id": "Q9BY49-1", "name": "Peroxisomal trans-2-enoyl-CoA reductase", "aln": "--MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSLYTHSYEVPDHDNWPKGAGDLSVVKKMKETFKEKAKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AAA9TYP4-1", "uniprot_id": "A0AAA9TYP4_BOVIN", "id": "A0AAA9TYP4-1", "name": "Peroxisomal trans-2-enoyl-CoA reductase", "aln": "MAVNSWVKGKSCLAAGLLQHQVAIVTGGGTGIGKAIVNELLHLGCNVVIASRKFDRLKSAADELNASLSPTVQAQVTPIKCNIRNEEEVNNLVKSTLDIYGKINFLVNNGGGQFFSPAEKISSKGWNAVIETNLTGTFYMCKAVYNSWMKEHGGSIVNITVLTKNGFPGAVHSGAAREGVYNLTKSLALEWASSGVRINSVAPGTIYSETAFSNYDYLTKDLLNKYIQKIPAKRFGFPEEVSSLVCFLLSPAASFVTGQLVYVDGGQSLYTQLFEIPDHDNWPQGAGDPSLVKSIKESSNHKAKL", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A4X1UM42-1", "uniprot_id": "A0A4X1UM42_PIG", "id": "A0A4X1UM42-1", "name": "Peroxisomal trans-2-enoyl-CoA reductase", "aln": "--MSFGVKGKSFLAAGCLQHQVAVVTGGGTGIGKAITSELLHLGCNVVIASRKFDRLKSTADELMASLPSASKAQVTPIKCNIRNEEEVNSLVKSTLDVYGKINFLVNNGGGQFISSAEDISSKGWQAVIETNLTGTFYMCKAVYKAWMKNHGGSIVNIILTTKNGNPHMAHSGAAREGVCNLTKSLALEWANSGIRINCVAPGSVYSQTASDNYGPAGQVLFEGFYEKIPAKRLGVPEEISPLVCFLLSPAASFITGQVVDVDGGQSLNLQGFEIADHDNWPEGAGDLSVVKRMKESYKKRAKL", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q99MZ7-1", "uniprot_id": "PECR_MOUSE", "id": "Q99MZ7-1", "name": "Peroxisomal trans-2-enoyl-CoA reductase", "aln": "--MGSWKTGQSYLAAGLLKNQVAVVTGGGTGIGKAVSRELLHLGCNVVIASRKLDRLTAAVDELRASLPPSSSAEVSAIQCNIRKEEEVSNLVKSTLAKYGKINFLVNNGGGQFMAPVEDITAKGWHAVIETNLTGTFYMCKEVYNSWMREHGGSIVNIIVLLNNGFPTAAHTGAAREGVYNLTKSMALAWASSGVRINCVAPGTIYSQTAVDNYGEMGQTLFEMAFDSIPAKRLGVPEEISPLVCFLLSPAASYITGQLINVDGGQALYTHAFSIPDHDNWPVGAGDLSIVKRIKESFKKKAKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WVK3-1", "uniprot_id": "PECR_RAT", "id": "Q9WVK3-1", "name": "Peroxisomal trans-2-enoyl-CoA reductase", "aln": "--MGSWKSGQSYLAAGLLQNQVAVVTGGATGIGKAISRELLHLGCNVVIASRKLDRLTAAVDELRASQPPSSSTQVTAIQCNIRKEEEVNNLVKSTLAKYGKINFLVNNAGGQFMAPAEDITAKGWQAVIETNLTGTFYMCKAVYNSWMKDHGGSIVNIIVLLNNGFPTAAHSGAARAGVYNLTKTMALTWASSGVRINCVAPGTIYSQTAVDNYGELGQTMFEMAFENIPAKRVGLPEEISPLVCFLLSPAASFITGQLINVDGGQALYTRNFTIPDHDNWPVGAGDSSFIKKVKESLKKQARL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8C2MS24-1", "uniprot_id": "A0A8C2MS24_CRIGR", "id": "A0A8C2MS24-1", "name": "Peroxisomal trans-2-enoyl-CoA reductase", "aln": "--MDFRTKGQSCLATGLLKNQVAVVTGGATGIGKAISRELLHLGCNVVIASRNLDRLNSAAEELRTSLPPSSRAQVTAIRCNIRKEEEVNNLVSATLAKYGKINFLVNNGGGQFLSPIEDISAKGWQAVIETNLTGTFYLCKAVYNSWMKKHGGSIVNIIVLINNGFPAASHSGAAREGVYNLTKSMALAWASSGVRINCVAPGVIYSQTAVDNYGELGQSMFEKAFDNIPAKRIGIPEEVSSLVCFLLSPAASFITGQLVNVDGGQSLYSHSVSIPDHDNWPEGVGDFSVVRRMKESFKK-SKL", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .*:* **.* *: ***:****.******: ***.**.*******:::**.::.:** :. ..: :.* .*:****:****..**.:** :*********.****::. *.*::***:**:*********:** **.:**:.******** : : * * *:**** ** ****::** ** **:***.**** :**:** .**. : ::: :.*****.*.***:*.:**********::*** : ****::* : :.****** *.** *.:: :**: :. ::*", "identical_positions": 165, "similar_positions": 87, "identity": "54.1%" }, { "cls_id": "homologset.oma.827495", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0PJE2-1", "uniprot_id": "DHR12_HUMAN", "id": "A0PJE2-1", "name": "Dehydrogenase/reductase SDR family member 12", "aln": "---MSLYRSVVWFAKGLREYTKSGYESACKDFVPHDLEVQIPGRVFLVTGGNSGIGKATALEIAKRGGTVHLVCRDQAPAEDARGEIIRESGNQNIFLHIVDLSDPKQIWKFVENFK-QEHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIP------VLEKEH-DPRVITVSSGGMLVQKLNTNDLQSE------RTPFDGTMVYAQNKRQQVVLTERWAQGHP--AIHFSSMHPGWADTPGVRQAMPGFHARFGDRLRSEAQGADTMLWLALSSAAAAQP--SGRFFQDRKPVSTHLPLATASSSPAEEEKLIEILEQLAQTFK----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0XC11-1", "uniprot_id": "A0A8V0XC11_CHICK", "id": "A0A8V0XC11-1", "name": "", "aln": "---MSWYRNVVWFVKGLREYTRSGYETASKHFDPADLEVDVAGRSFLITGSNSGIGKAAAKEIARRGGTVHLVCRNKERAEDAKGEIVTETGNQNIFLHIVDISNPKEIWKFAEKFK-NEHKLNVLINNAGCMVNNRELTEDGLEKNFATNTLGTYVLTTALLP------LLEKEA-DARVVTVSSGGMLVQKLNISDLQSG------SETFDGTMVYAQNKRQQVVLTEQWAKTHR--SIHFSVMHPGWADTPAVRSSMPDFYQKMKNSLRTEAQGADTVVWLAVSSEAAKLP--SGLFFQDRQPVPTHLPLARTHSPPGDEEKLMEVLEEFSQKFKSTSPGSPQCH", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9SZ91-1", "uniprot_id": "Q9SZ91_ARATH", "id": "Q9SZ91-1", "name": "", "aln": "MFLLKTWRSTAFGVYGYMNFTKSGFLDHSKKFKPEDMQLQIEGKNCVVTGANSGIGFAAAEGLASRGATVYMVCRNKERGQEALSKIQTSTGNQNVYLEVCDLSSVNEIKSFASSFASKDVPVHVLVNNAGLLENKRTTTPEGFELSFAVNVLGTYTMTELMLP------LLEKATPDAKVITVASGGMYTSPLTT-DLQFS------GEKFDGVEQYARNKRIQVALTEKWADKYKNKGIGFYSMHPGWAETPGVAKSLPSFSESFAGKLRTSEQGADTIVWLALQ-PKEKLV--SGAFYFDRAEAPKHLKLAGTSKSHDLIDSVIDSVHSMAALNP----------", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q54IY2-1", "uniprot_id": "Q54IY2_DICDI", "id": "Q54IY2-1", "name": "Dehydrogenase/reductase SDR family member 12", "aln": "-----MITASKWFWNGLWNYTNRGFEKKKQHFNENDLNQDISSKHFIITGGNNGLGFQTSLELAKLGGNVHILCRNQEKGEQAINEIKDKSKSDKVHLHLCDVSIIGSIKSFVDDWKKQGNSVDVLIHNAGVMLPNREETSEGHEKTFATNLLGPFLLTKLLMCDDNNSGSGSGEGAHKRVIFVSSGGMLTSKMSK-DFEFKKFTTNKNLKWDGMRAYAETKRAIIYLTELFSQNYQ--SFNSYSMHPGWVNTTGVMNGMPLFYKMTKSQLRTLEQGCDTIVWLAVSPTVEDHSKYSGQFFEDRQIVDKFIHNSHTESSQEDINSLWNYLNEIFLKSC----------", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ::*. *: :.* *:: :: .: ::**.*.*:* :: :* *..*:::**:: .::* .:* .: .:::.*.: *:* .* .*...: : :.**::*** : :* * :* * .**.* ** : :* :: . . :*: *:**** .. :. *:: :** **..** : *** ::. : .: *****.:*..* ..:* * . **: **.**::***:. ** *: ** . ..: : : .. :.: : :..: ", "identical_positions": 76, "similar_positions": 115, "identity": "21.84%" }, { "cls_id": "homologset.oma.827496", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q91WL8-1", "uniprot_id": "WWOX_MOUSE", "id": "Q91WL8-1", "name": "WW domain-containing oxidoreductase", "aln": "MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQ-VFFVDHINKRTTYLDPRLAFTVDD-NPTKPTTRQRYDGSTTAMEILQGRDFTGKVVLVTGANSGIGFETAKSFALHGAHVILACRNLSRASEAVSRILEEWHKAKVEA--MTLDLAVLRSVQHFAEAFKAKNVSLHVLVCNAGTFALPWGLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSSPARVIVVSSE-SHRFTDINDSSGKLDLSRLSPPRSDYWAMLAYNRSKLCNILFSNELHRRLSPR--GVTSNAVHPGNMMYSAIHRNSWVYKLLFTLARPFTKSMQQGAATTVYCAVAPELEGLGGMYFNNCCRCLPSEEAQSEETARALWELSERLIQDRLGSPSS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LQK5-1", "uniprot_id": "A0ABK0LQK5_RAT", "id": "A0ABK0LQK5-1", "name": "WW domain-containing oxidoreductase", "aln": "MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQ-VFFVDHINKRTTYLDPRLAFTVDD-NPTKPTTRQRYDGSTTAMEILQGRDFTGKVVLVTGANSGIGFETAKSFALHGAHVILACRNMSRASEAVSRILEEWHKAKVEA--MTLDLAVLRSVQHFAEAFKAKNVPLHILVCNAGTFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSAPARVIVVSSE-SHRFTDINDSSGKLDLSRLSLSSSDYWAMLAYNRSKLCNILFSNELHRLLSPR--GVTSNALHPGNMMFSAIHRNSWVYKLLFTLARPFTKSMQQGAATTVYCAVAPELEGLGGMYFNNCCRCLPSEEAQNEETARALWELSERLIQDRLGSPSS------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8C2MTK3-1", "uniprot_id": "A0A8C2MTK3_CRIGR", "id": "A0A8C2MTK3-1", "name": "WW domain-containing oxidoreductase", "aln": "MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRRRVAGDLPYGWEQETDENGQ-VFFVDHINKRTTYLDPRLAFTVDD-NPTKPTTRQRYDGSTTAMEILQGRDFTGRVVLVTGANSGIGFETAKSFALHGAHVILACRNMSRASEAVSRILEEWHKAKVEA--MTLDLAVLRSVQHFAEAFKAKNMSLHVLVCNAGTFALPWTLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSAPARVVVVSSE-SHRFTDINDSSGKLDLSRLSPSQSDYWAMLAYNRSKLCNLLFSNELHRRLSPR--GVTSNAVHPGNMMYSSIHRNSWVYMLLFTLARPFTKSMQQGAATTVYCAVAPELEGLGGMYFNNCCRCLPSEEAQSEETARALWDLSERLIQDRLGSPSS------", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q9NZC7-1", "uniprot_id": "WWOX_HUMAN", "id": "Q9NZC7-1", "name": "WW domain-containing oxidoreductase", "aln": "MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQ-VFFVDHINKRTTYLDPRLAFTVDD-NPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHKAKVEA--MTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSAPARVIVVSSE-SHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSKLCNILFSNELHRRLSPR--GVTSNAVHPGNMMYSNIHRSWWVYTLLFTLARPFTKSMQQGAATTVYCAAVPELEGLGGMYFNNCCRCMPSPEAQSEETARTLWALSERLIQERLGSQSG------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5F389-1", "uniprot_id": "WWOX_CHICK", "id": "Q5F389-1", "name": "WW domain-containing oxidoreductase", "aln": "MAALKYAGLEDTDSEEELPPGWEERTTKDGWVYYANHLEEKTQWEHPKSGKRKRVAGGLPYGWEQETDENGQ-VYFVDHINKRTTYLDPRLAFTVED-NPAKPPTRQKYDGNSTAMEILQGRDLSGKVIIITGANSGIGFETAKSFALHGAYVILACRNMSRGNDAVQRILEEWHKAKVEA--MTLDLASLRSVQNFAEAFKSKNMPLHILVCNAAIFGSSWCLTEDGLESTFQVNHLGHFYLVQLLEDILRRSSPARVVVVSSE-SHRFTEIKDSSGKLDFSLLSPSKKEYWAMLAYNRSKLCNILFSNELNRRLSPH--GVTSNSVHPGNMIYSSIHRNWWVYTLLFTLARPFTKSMQQGAATTVYCATAAELEGLGGMYFNNCCRCLPSAEARNELTAVALWELSERLIREQLGRRSP------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9VLU5-1", "uniprot_id": "WWOX_DROME", "id": "Q9VLU5-1", "name": "WW domain-containing oxidoreductase", "aln": "MIALP-----DTDSEDELPPGWEERATDDGTVCYVNQQGKTSQWTHPRTGRSKRITGELPLGWEKYYDEQGKRFMFLNKETQQRTNVDPRLAFAVEEPTQNVAQVRQRFDSCSTALQVLHGKDLHGRTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARSRCRFAALDLSSLRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTRTVDGLETTFQVSHLSHFYLTLQLETLFDYKT--RIIVLSSE-SHRFANLP--VENLAVHHLSPPPEKYWSMMAYNNAKLCNVLFAQELAQRWKQR--GISVFSLHPGNMVSSDLSRNYWFYRLLFAIVRPFTKSLQQAAATSIYCATANELTGLSGLYFNNCFFCEPSKLSKSAALQQQLWKLSENLIAELVEQEQH------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "F4KCF2-1", "uniprot_id": "F4KCF2_ARATH", "id": "F4KCF2-1", "name": "", "aln": "------------------------------------------------MGLYSLITGRRGP---------------------------------------------SGFGSASTAEEVTQGIDATNLTAIITGGTGGIGMETARVLSKRGAHVVIGARNMGAAENAKTEILRQNANARVTL--LQLDLSSIKSIKAFVREFHALHLPLNLLINNAGVMFCPYQLSEDGIELQFATNHIGHFLLTNLLLDTMKNTAKTSGVEGRILNVSSVAHIYTYQEGIQFDSIN-DICSYSDKRAYGQSKLANILHANELSRQLQEEGVNITANSVHPGLILTNLFQHTALLMRFLKFFSFYLWKNIPQGAATTCYVALHPSVKGVTGKYFADCNEVTPSKLARDETLAQKLWDFSVKLINSVSKKNYLGFDDTT", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::* . :.. :** :: :* * . . ::**.. *** ***: :: :*. :::..** . .. * .* .: *: ***: ::*:: *.. :: :. *: **. : .: : **:* * ..*:.** *. * : .: : .:.: : . :. .* **..:**.*:*.::** : . . .:: ::*** :: . : :. . :* : : *.: *.***: * * .: *: * ** :* ** ::. ** :* .** . ", "identical_positions": 69, "similar_positions": 109, "identity": "16.16%" }, { "cls_id": "homologset.oma.827498", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TC12-1", "uniprot_id": "RDH11_HUMAN", "id": "Q8TC12-1", "name": "Retinol dehydrogenase 11", "aln": "---MVELMFPL-----LLLLLPFLLYMAAPQIRKMLSSGVCTSTVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTHLLLEKLKESAPS-----RIVNVSSLAH---HLGRIHFHNLQGEK--FYNAGLAYCHSKLANILFTQELARRLK--GSGVTTYSVHPGTVQSELVR--HSSFMRWMWWLFSFFIKTPQQGAQTSLHCALTEGLEILSGNHFSDCHVAWVSAQARNETIARRLWDVSCDLLGLPID----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1BM93-1", "uniprot_id": "E1BM93_BOVIN", "id": "E1BM93-1", "name": "NADP-retinol dehydrogenase", "aln": "---MVGVLL-------LLLLLPFLLYIAAPQIRKMLSSGVCTSTIQLPGKVAVVTGANAGIGKETAKELARRGARVYLACRDVQNGELVAREIQMMTGNQQVLVRKLDLADTKSIRAFAKRFLEEEKHLHILINNAGVMMCPYSKTADGFEMHMGVNHLGHFLLTHLLLEKLEESAPS-----RVVNVSSLAH---LLGRIHFHNLQGEK--FYQSGLAYCHSKLANILFTQELARRLKASGSGVTVYSVHPGTVNSELVR--HSALMRWIWWIFSFFIKTPQQGAQTSLYCALTEGLEVLSGNHFSDCHVAWVSAQARNETVARRLWDVSCDLLGIPVDWLMMAAGPKRSLKQTTQHTLPK", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q9QYF1-1", "uniprot_id": "RDH11_MOUSE", "id": "Q9QYF1-1", "name": "Retinol dehydrogenase 11", "aln": "---MFGFLL--------LLSLPFILYLVTPKIRKMLSSGVCTSNVQLPGKVAIVTGANTGIGKETAKDLAQRGARVYLACRDVDKGELAAREIQAVTGNSQVFVRKLDLADTKSIRAFAKDFLAEEKHLHLLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTHLLLEKLKESAPS-----RIVNLSSLGH---HLGRIHFHNLQGEK--FYSAGLAYCHSKLANILFTKELAKRLK--GSGVTTYSVHPGTVHSELTR--YSSIMRWLWQLFFVFIKTPQEGAQTSLYCALTEGLESLSGSHFSDCQLAWVSYQGRNEIIARRLWDVSCDLLGLPVDW---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E1BTL3-1", "uniprot_id": "E1BTL3_CHICK", "id": "E1BTL3-1", "name": "NADP-retinol dehydrogenase", "aln": "MEPAAGMLSCWGAVLGAAVSVPLLLLAAAPYVRRYVAGGRCRSTARLDGKVAVITGANTGIGKETARELARRGARVIVACRDIAKAEAAAREIRAETDNQEVIVKKLDLADTRSIREFANSFLAEEKELHILINNAGVMLCPYSKTADGFEMHLGVNHLGHFLLTFLLLERLKQSAPS-----RIVNVSSLAH---HGGRIRFHDLNGEK--SYNRGLAYCHSKLANVLFTRELARRLQ--GTKVTANSLHPGSVHSELVR--HSFVMTWLWRIFSFFLKTPWEGAQTSVYCAVAEELESVTGQYFSDCQPAYVSPWGRDDETAKKLWNVSCELLGIQWD----------------------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "O22985-1", "uniprot_id": "O22985_ARATH", "id": "O22985-1", "name": "", "aln": "---------------MIETGKYLLGAAGASGFGSKSTAEEVTENCDLRSITAVITGATSGIGAETARVLAKRGARLIFPARNVKAAEEAKERIVSEFPETEIVVMKLDLSSIASVRNFVADFESLDLPLNLLINNAGKLAHEHAISEDGIEMTFATNYLGHFLLTNLLLNKMIQTAEETGVQGRIVNVTSGIHGWFSGDLIEYLRLISQPKCQFDATRAYALSKLANVLHTKELSSRLQKIGANVTVNCVHPGVVRTRLTRDREGLLTDLVFFLASKLVKTVPQAAATTCYVATNPRLVNVSGKYFTDCNETTPSGLGTNSSEATKLWAASEILVTQHSKTSFDPCS---------------", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :. . :. .. * . ..::***.:*** ***: **:****: ...*:: .* . ..* : ::.* ****:. *:* *. * : *::****** : :: : **:** :..*:******* ***::: ::* . *:**::* * . *.: * .: :. **. *****:*.*:**: **: *: **. .:*** *.:.*.* . . :: : ::** :.* *: : * * ::*.:*:**: : * . :. * :** .* *: . ", "identical_positions": 96, "similar_positions": 103, "identity": "26.52%" }, { "cls_id": "homologset.oma.827500", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P16152-1", "uniprot_id": "CBR1_HUMAN", "id": "P16152-1", "name": "Carbonyl reductase [NADPH] 1", "aln": "MSSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVHQKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKATKSPEEGAETPVYLALLPPDAEGPHGQFVSEKRVEQW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3SZD7-1", "uniprot_id": "CBR1_BOVIN", "id": "Q3SZD7-1", "name": "Carbonyl reductase [NADPH] 1", "aln": "MSSSNCVALVTGANKGIGFVIVRDLCRRFSGDVVLTARDEARGRAAVQQLQAEGLSPLFHQLDIDDRQSIRALRDFLRKEYGGLDVLVNNAGIAFKTADTTPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQGRVVNVSSFVSVNSLKKCSRELQQKFRSETITEEELVGLMNKFVEDTKNGVHRKEGWPDTAYGVTKIGVTVLSRIHARKLSEQRGGDKILLNACCPGWVRTDMGGPKASKSPEEGAETPVYLALLPSDAEGPHGEFISEKRVVQW", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "P48758-1", "uniprot_id": "CBR1_MOUSE", "id": "P48758-1", "name": "Carbonyl reductase [NADPH] 1", "aln": "MSSSRPVALVTGANKGIGFAITRDLCRKFSGDVVLAARDEERGQTAVQKLQAEGLSPRFHQLDIDNPQSIRALRDFLLKEYGGLDVLVNNAGIAFKVNDDTPFHIQAEVTMKTNFFGTRDVCKELLPLIKPQGRVVNVSSMVSLRALKNCRLELQQKFRSETITEEELVGLMNKFVEDTKKGVHAEEGWPNSAYGVTKIGVTVLSRILARKLNEQRRGDKILLNACCPGWVRTDMAGPKATKSPEEGAETPVYLALLPPDAEGPHGQFVQDKKVEPW", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***. ******.*****:.*.***** *******:*** **::***:******** *******: ********** ******************. * **********************.*****************::*:.:**.* ****************************:*** :****.:*************** ****.*** ******************.****:*****************.*******:*:.:*:* *", "identical_positions": 229, "similar_positions": 31, "identity": "82.67%" }, { "cls_id": "homologset.oma.827502", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P35270-1", "uniprot_id": "SPRE_HUMAN", "id": "P35270-1", "name": "Sepiapterin reductase", "aln": "MEG-------GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAG----------------------------------SLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYDK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A480ZCU6-1", "uniprot_id": "A0A480ZCU6_PIG", "id": "A0A480ZCU6-1", "name": "Sepiapterin reductase", "aln": "MEHGV-GKVGGLGRALCVVTGASRGFGRTLAQLLAPLLSPGSVLVLTARNDEALRHLEAELGSERPDLRVVRVPADLGAEAGLQQLLGALRELPRPEGLQRVLLFNNAA----------------------------------SLGDVSKSFVDLTDSAEVNSYWALNLTSMLCLTSSFLKAFPDSPGLSRMVVNISSICAVKPFKGWALYCAGKAARDMIYQVLAAEDPSLRVLSYAPGPLDTDMQQIAREASVDPDLRKRLQELKRKGELVDCKVSAQKLLNLLQKDEFKSGAHVDFYN-", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "P18297-1", "uniprot_id": "SPRE_RAT", "id": "P18297-1", "name": "Sepiapterin reductase", "aln": "MEG------GRLGCAVCVLTGASRGFGRALAPQLAGLLSPGSVLLLSARSDSMLRQLKEELCTQQPGLQVVLAAADLGTESGVQQLLSAVRELPRPERLQRLLLINNAG----------------------------------TLGDVSKGFLNINDLAEVNNYWALNLTSMLCLTTGTLNAFSNSPGLSKTVVNISSLCALQPFKGWGLYCAGKAARDMLYQVLAVEEPSVRVLSYAPGPLDTNMQQLARETSMDPELRSRLQKLNSEGELVDCGTSAQKLLSLLQRDTFQSGAHVDFYDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8V0ZD26-1", "uniprot_id": "A0A8V0ZD26_CHICK", "id": "A0A8V0ZD26-1", "name": "Sepiapterin reductase", "aln": "MEAEPGAERRRWAAASCVLTGASRGFGRSLARLLAPRLGPGSLLLLLARSEEALAQLAAELRDSCPGLRVECVASDLGSEEGLRRAVGAVRELLPGGPPDRLLLINNAGNATTGIGPQVLVQKKREQQESVVTPEDFAPGAEGSLGDISKSFLSLTDPNEINTYFAFNITSALCLTSSALQAFGMRPGCSRTVVNISSLCALQPFRSWALYCSGKAARDMMFRVLAAEEPDVRVLNYAPGPLDTDMQLLARTRTGDAEMRQQFQSLHDSGQLIDCAVSAQKLLRLLEENTFTSGAHMDFYSV", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . * *::*********:** ** *.***:*:* **.:. * :* ** . ..*:* ..:***:* *::: :.*:*** :*:**:***. :***:**.*:.:.* ::*.*:*:*:** ****:. *:** ** .: ******:**::**:.*.***:*******:::*** *:*.:***.********:** :** : *.::*. :*.*: .*:*:** .****** **:.: * ****:***. ", "identical_positions": 133, "similar_positions": 80, "identity": "44.04%" }, { "cls_id": "homologset.oma.827503", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A287A1V9-1", "uniprot_id": "A0A287A1V9_PIG", "id": "A0A287A1V9-1", "name": "Peroxisomal reductase activating PPAR-gamma", "aln": "-----------------MDLITSTATLPLLFGCVGVFGLLKLLQWLRTRAYVRDAVVVITGATSGLGRECARAFSAAGARLVLCGRNAEALEELSRELAASPAAKVQTHKPHTVTFDLADPGAIVGAAAEILRCFGHVDVLINNAGISYRGAVVDTSLDVDKRVMETNYFGPVALTKALLPSMIRRRQGHIVAISSIQGRISIPFRSAYAASKHATQAFFDCLRAEVEQHGVEVTVISPGYIHTHLSLNALTADGSKYGVMDESTAQGRSPAEVARDVLAAVGQRKKDVVLAGLAPSLAVYLRTLAPGLFFSLMASRARK-ERKSKHC-", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0ABI0P6C2-1", "uniprot_id": "A0ABI0P6C2_BOVIN", "id": "A0ABI0P6C2-1", "name": "Peroxisomal reductase activating PPAR-gamma", "aln": "-----------------MDFITSTAILPLLLGCVGLFSLFKLLQWLRMRAYVRNAVVVITGATSGLGRECARVFHAAGARLVLCGRNAEALEELSQELAASRAPEVQTHKPCTVTFDLADPGAIAGAASEILQCFGHVDVLINNAGISYRGAIVDTSPDVDKRVMETNYFGPVALTKALLPAMIRRRQGHVVAISSIQGKISLPFRSAYAASKHATQAFFDCLRAEVEQHDIEVTVISPGYIHTNLSLNAVTADGSKYGVMDETTAQGRSPVQVAQDILAALGKKKKDVVLADPMPSLAVYLRTLAPGLFFRLMASRARK-ERKSKHS-", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q6IAN0-1", "uniprot_id": "PEXRP_HUMAN", "id": "Q6IAN0-1", "name": "Peroxisomal reductase activating PPAR-gamma", "aln": "MVSPATRKSLPKV--KAMDFITSTAILPLLFGCLGVFGLFRLLQWVRGKAYLRNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAITADGSRYGVMDTTTAQGRSPVEVAQDVLAAVGKKKKDVILADLLPSLAVYLRTLAPGLFFSLMASRARK-ERKSKNS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RJY4-1", "uniprot_id": "PEXRP_RAT", "id": "Q5RJY4-1", "name": "Peroxisomal reductase activating PPAR-gamma", "aln": "MISPSSRKGMLKE--RAMDLVTQTTILPLLFGCLGIFSLFRLLQRTRSKAYLRNAVVVVTGATSGLGKECARVFHAAGAKVVLCGRNVKALEEFTRELADSSSSQGQTHQPCVVTFDLADPGAIAPAAAEILQCFGYVDILINNAGISYRGAISDTIVDVDRKVMEINYFGPVALTKALLPSMVERKRGHIVAISSIQGKISIPFRSAYAASKHATQAFFDCLRAEMKDSDIEVTVISPGYIHTNLSVNAVTADGSRYGALDKNTAQGRSAVEVAQDIFDAVGKKKKDVLLTDFLPTMAVYIRTLAPRLFFRIMASRARK-ERKSKNS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J47-1", "uniprot_id": "PEXRP_MOUSE", "id": "Q99J47-1", "name": "Peroxisomal reductase activating PPAR-gamma", "aln": "MISPSFRKGMLKE--RVMDLASQTTILPLLFGCLGIFSLFRLLQRIRSKAYLRNAVVVVTGATSGLGRECAKVFHAAGAKLVLCGRNVKALEELSRELAGS--SQGQTHQPFVVTFDLADPGTIAAAAAEILQCFGYVDVLINNAGISYRGTISDTIVDVDRKVMEINYFGPVALTKALLPSMVERKQGHIVAISSIQGKISIPFRSAYSASKHATQAFFDCLRAEMEEANIKVTVISPGYIHTNLSVNAVTADGSRYGALDKNTAQGRSAAEVAQDVFDAVGKKKKDVLLTDFVPSMAVYIRTLAPGLFFRIMASRARK-ERKSKSS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A3Q2UBH5-1", "uniprot_id": "A0A3Q2UBH5_CHICK", "id": "A0A3Q2UBH5-1", "name": "Peroxisomal reductase activating PPAR-gamma", "aln": "-----------------MDLTS-TVIIPLLFGSLGLFSLFRLLQWMRMRAYLRGAVVVVTGATSGLGKECAKAFHAAGSRLVLCGRDSEKLKDLAQELSAMTDHRKNIHKPHTVVFDLSDTKTILNAAEEILKHLGHVDILINNAGISYRGTIVDTGLDVDKKVMETNYFGPIALTKALLPSMIKRRQGHIVAISSVQGKISIPFRSAYAASKHATQAFFDCLRAEVEQYDIDVTVISPGYIQTNLSLNAVTADGSRYGVMDKNTAEGKTAAEVAQVVLCAVGQKKKEVLIAGLKPSLAVYLRNLFPRLFFNLMAARAKK-ERKTKDS-", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9Y140-1", "uniprot_id": "DHRS7_DROME", "id": "Q9Y140-1", "name": "Dehydrogenase/reductase SDR family protein 7-like", "aln": "MKVQDMDKCAPSSDWNVLYWVLGTVLMPVALP-LAIINIWQRFQAQKFRNQLPGKVVLITGASSGLGESLAHVFYRAGCRVILAARRTQELERVKKDLLALD--VDPAYPPTVLPLDLAELNSIPEFVTRVLAVYNQVDILINNGGISVRADVASTAVDVDLKVMVVNYFGSVALTKALLPSMVKRGSGHICFISSVQGKFAIPQRAAYSASKHAMQAFADSLRAEVANKNINVSCVSPGYIRTQLSLNALTGSGSSYGKVDETTAKGMSPDKLAERILQCILRKEPDIIVSDVQAKIAYYLRHLCPSLYFWIMAKRAVKLENAEKKST", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. :*: : :.::.: : :* : : : . **::***:****.. *:.* **.:::*..* *: . ::* : * : :**:: :* . .:* . **:*:**.*** *. : .* *** :** ****.:********:*:.* **: ***:**::::* *:**:***** *** *.****: : :.*: :*****:*:**:**:*..** ** :* .**:* :. ::*. :: .: ::: :::::. ..:* *:* * * *:* :** ** * *. * . ", "identical_positions": 113, "similar_positions": 106, "identity": "34.35%" }, { "cls_id": "homologset.oma.827504", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IPP8-1", "uniprot_id": "Q8IPP8_DROME", "id": "Q8IPP8-1", "name": "Ketoreductase domain-containing protein", "aln": "---------------------------------MNFAGKVVLITGASSGIGAATAIKFAKYGACLALNGRNVENLKKVAAECSKVSQSQPALVVGDIAKEADTQRIWSETLQQYGKLDVLVNNAGI---IETGTIETTSLEQYDRVMNTNLR-AIYHLTMLATPELVKTKGNIVNVSSVNGIRSFPGVLAYNISKMGVDQFTRCVALELAAKGVRVNCVNPGVTVTNLHARGGMDAETYKKFLEH------SKTTHALGRPGDVKEVAAAIAFLASDEASFSTGVSLPVDGGRHAMCPR-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9LW35-1", "uniprot_id": "Q9LW35_ARATH", "id": "Q9LW35-1", "name": "", "aln": "MWRSFARSFKLINVPNGLISKPIRSTLLYSTSSRKLEGKVAVITGGASGIGKATAEEFVSQGAQVIIVDIDEEAGHMVATELG----SAAHFLRCDVTEEEQIAKAVETAVTRHGKLDVMLNSAGISCSISPPSIADLDMDTYDKVMRLNVRGTVLGIKHAARAMIPAGSGSILCLSSISGLMGGLGPHAYSISKFTIPGVVKTVASELCKHGLRINCISPAGIPTPLTLRMFREAFAGHSIREEQLLAIVNATGELKGEKCEEIDVAKAALYLASDDAKFVTGHNLVVDGGFTCFKSLNLPSA", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ***.:***.:**** *** :*.. ** : : . : * : **:* . * . :: *:::* : : . :: ::*****::*.*** *.. :* .:: **:**. *:* :: :. * . : .*.*: :**:.*: . * **.***: : ..: ** **. :*:*:**:.*. * * * :* : :.: *. . * . *. : :** * :****:*.* ** .* **** .: . ", "identical_positions": 84, "similar_positions": 86, "identity": "27.63%" }, { "cls_id": "homologset.oma.827505", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O75911-1", "uniprot_id": "DHRS3_HUMAN", "id": "O75911-1", "name": "Short-chain dehydrogenase/reductase 3", "aln": "MVWKRLGALVMFPLQMIYLVVKAAVGLVLPAKLRDLSRENVLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEMFQGMRVRFPNLFPPLKPETVARRTVEAVQLNQALLLLPWTMHALVILKSILPQAALEEIHKFSGTYTCMNTFKGRT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1N334-1", "uniprot_id": "F1N334_BOVIN", "id": "F1N334-1", "name": "Short-chain dehydrogenase/reductase 3", "aln": "MVWKRLGALVVFPLQMIYLVVKAAVGLVLPAKLRDLSRENVLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEMFQGMRVRFPNLFPPLKPETVARRTVEAVQLNQALLLLPWTMHALIILKSILPQAALEEIHKFSGTYTCMNTFKGRT", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1RF61-1", "uniprot_id": "F1RF61_PIG", "id": "F1RF61-1", "name": "Short-chain dehydrogenase/reductase 3", "aln": "MVWKWLGALVVFPLQMIYLVVKAAIGLVLPAKLRDLSRENVLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEMFQGMRVRFPNLFPPLKPETVARRTVEAVQLNQTLLLLPWTMHVLIILKSILPQAALEEIHRFSGTYTCMNTFKGRT", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "O88876-1", "uniprot_id": "DHRS3_MOUSE", "id": "O88876-1", "name": "Short-chain dehydrogenase/reductase 3", "aln": "MVWKWLGALVVFPLQMIYLVTKAAVGMVLPPKLRDLSRESVLITGGGRGIGRHLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQMAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHVNTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEMFQGMRVRFPNLFPPLKPETVARRTVDAVQQNQALLLLPWTMNILIILKSILPQAALEEIHRFSGTYTCMNTFKGRT", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** *****:*********.***:*:***.********.************:**************************************************** ***************************************:*********************************************************************************************************:*** **:********: *:***************:***************", "identical_positions": 285, "similar_positions": 13, "identity": "94.37%" }, { "cls_id": "homologset.oma.827507", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NBN7-1", "uniprot_id": "RDH13_HUMAN", "id": "Q8NBN7-1", "name": "Retinol dehydrogenase 13", "aln": "MSRYLLPLSALGTVAGAAVLLKDYVTGGACPSKATIPGKTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNHHVNARHLDLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAG---HIDFDDLNWQTRK-YNTKAAYCQSKLAIVLFTKELSRRLQ--GSGVTVNALHPGVARTELGR-HTGIHGSTFSSTTLGPI-------------------------------FWLLVK-----------------------SP----------------ELAAQPSTYLAVAEELADVS----------------------------------GKYFDGLKQKAPAPEAEDEE-----------VARRLWAESARLVGLEAPS-------------VREQPLPR-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A286ZWN9-1", "uniprot_id": "A0A286ZWN9_PIG", "id": "A0A286ZWN9-1", "name": "NADP-retinol dehydrogenase", "aln": "MNRYILPLSVLGTAVGGAVLLKDFVAGGACPSKATIPGKTVIVTGANTGIGKQTALELAKRGGNIILACRDLEKCEAAAKDIRGETLNHRVSARHLDLASLTSVREFAAKINEEEEHLHVLINNAAVMRCPHWTTEDGFEMQLGVNYLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAG---HIDFDDLNWEKRK-YDTKAAYCQSKLALVLFSMELSRRLQ--GTGVTVNALHPGVARTELGR-HTGMHNSAFSSFTLGPI-------------------------------FWLLVK-----------------------SP----------------QLAAQPSTYLAVAEELESVS----------------------------------GKYFDGFREKAPAPEAEDEE-----------VAQRLWAESARLVGLELSSGAS----------ERGQPLPK-------------------------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q8CEE7-1", "uniprot_id": "RDH13_MOUSE", "id": "Q8CEE7-1", "name": "Retinol dehydrogenase 13", "aln": "MSRFLLPVSVVGTVIGGTVLLKDYVAGGACPSKATIPGKTVIVTGANTGIGKQTALELAKRGGNVILACRDMEKCEVAAKDIRGETLNPRVRAERLDLASLKSIREFARKVIKEEERVDILVNNAAVMRCPHWTTEDGFEMQFGVNYLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAG---HIDFEDLNWQMKK-YDTKAAYCQSKLAVVLFTKELSHRLQ--GSGVTVNALHPGVARTELGR-HTGMHNSAFSGFMLGPF-------------------------------FWLLFK-----------------------SP----------------QLAAQPSTYLAVAEELENVS----------------------------------GKYFDGLREKAPSPEAEDEE-----------VARRLWTESARLVGLAMAHGSP----------GRGHAIPR-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AG15-1", "uniprot_id": "A0A8I6AG15_RAT", "id": "A0A8I6AG15-1", "name": "", "aln": "MNRFLLPVSVVGTVIGGTVLLKDYVAGGACPSKATIPGRTVIVTGANTGIGKQTALELAKRGGNIILACRDREKCEAAAKDIRGETLNPRVRAEHLDLASLKSIREFAGKIIKEEERVDILVNNAAVMRCPHWTTKDGFEMQFGVNHLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAG---HIDFEDLNWQIKK-YDTKAAYCQSKLAVVLFTKELSRRLQ--GTGVTVNALHPGVARTELGR-HTGMHNSAFSGFMLGAYKEKPSLTIDSGPQGFSKRNVTLVCHTHHFFDLFILCRDGNASFPRNCLQQDHNTFLISPVSPGYKRTYRCFVSPKVNSYLWSLPSDPLELLVPGPSVSPIVVWVTVAAVCFLIFFLLLLYLCHHWAKCKTSSAKTRTQVKYKSSSPAMDNDEKIKYDELECIQPENYCQVDTKKLSAVEDSKEVTYAQLCQEIFLENMDSLPSNTLHHMSTQTCVYATLRLSQEESQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q54BI7-1", "uniprot_id": "Q54BI7_DICDI", "id": "Q54BI7-1", "name": "", "aln": "--------------------------------MNKLNNKVAIITGGSDGIGKETCKIIAREIGTIVIGCRNKQKGEVAAKEISSHTGNSNIIILDLDLSKQNSVKSFVNEFNKLNLPLDLLINNAGVMCPPFSITQDGYSFQIATNHFGPFLLTNLLLKNLEKSENPRILVLTSDRFKDADLSLILNDKINVESEANYNQLKDYSLSKCCNLLFTKELQRKLIEKGSKIVVNSINPGKVQTSLQRDFTGILKVAFS---LMPN--------------------------------FIFTP----------------------------------------IQVASKECAKVALGTDPSLNG--------------------------------IKGSYFNIGVLTETPRQFNSIE-----------ISKKLWDITSKFTNISNDLVLK-------------------------------------------", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .:..*:**.. ****:*. :*:. *.:::.**: :* *.***:* ..* * .: ***:. .*::.*. :. : : :.:*:***.** *. *:**:.:*:..*::* ********.:*: * .**: *:* . . * :.:* : . *: *. ** . :**: **.::* *: :.**:::** .:*.* * .**: :** * . ::: : : . : : . .. . .. :. * . : :: : ", "identical_positions": 77, "similar_positions": 108, "identity": "15.68%" }, { "cls_id": "homologset.oma.827511", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BVI4-1", "uniprot_id": "DHPR_MOUSE", "id": "Q8BVI4-1", "name": "Dihydropteridine reductase", "aln": "---MAASGEARRVLVYGGRGALGSRCVQAFRARNWWVASIDVVENEEASASVVVKMTDSFTEQADQVTADVGKLLGDQKVDAILCVAGGWAGGNAKSKSLFKNCDMMWKQSMWTSTISSHLATKHLKEGGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKNSGMPPGAAAIAVLPVTLDTPMNRKSMPEADFSSWTPLEFLVETFHDWITGNK-RPNSGSLIQVVTTDGKTELTPAYF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3HR10-1", "uniprot_id": "G3HR10_CRIGR", "id": "G3HR10-1", "name": "Dihydropteridine reductase", "aln": "---MAASGEARRVLVYGGRGALGSRCVQAFRARNWWVASIDVVENEEASASVIVKMTDSFTEQADQVTAEVGKLLGDQKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSMWTSTISSHLATKHLKEGGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKNSGMPPGAAAIAVLPVTLDTPMNRKSMPEADFSSWTPLEFLVETFHDWITGNK-RPNSGSLIQVVTTEGKTELTPAYF", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "P09417-1", "uniprot_id": "DHPR_HUMAN", "id": "P09417-1", "name": "Dihydropteridine reductase", "aln": "MAAAAAAGEARRVLVYGGRGALGSRCVQAFRARNWWVASVDVVENEEASASIIVKMTDSFTEQADQVTAEVGKLLGEEKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSIWTSTISSHLATKHLKEGGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKNSGMPPGAAAIAVLPVTLDTPMNRKSMPEADFSSWTPLEFLVETFHDWITGKN-RPSSGSLIQVVTTEGRTELTPAYF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSU6-1", "uniprot_id": "Q9VSU6_DROME", "id": "Q9VSU6-1", "name": "Dihydropteridine reductase", "aln": "---MSAG----RVVIYGGKGALGSACVDHFKANNYWVGSIDLTENEKADVSIVVPRDASWVEQEETVVSKVGESLAGEKLDAVICVAGGWAGGNAK-KDLAKNADLMWKQSVLTSAISAAVAAQHLKAGGLLALTGAKPALEGTPGMIGYGMAKAAVHQLTRSLGAEKSGLPAGSLAVSILPVTLDTPMNRKWMPDADFGTWTPLTEVAGLFLKWTQDQE-RPKTGSLLQLITTNGITQLIAAE-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q86A17-1", "uniprot_id": "DHPR_DICDI", "id": "Q86A17-1", "name": "Dihydropteridine reductase", "aln": "---MSKN-----ILVLGGSGALGAEVVKFFKSKSWNTISIDFRENPNADHSFTIK--DSGEEEIKSVIEKINSKS--IKVDTFVCAAGGWSGGNASSDEFLKSVKGMIDMNLYSAFASAHIGAKLLNQGGLFVLTGASAALNRTSGMIAYGATKAATHHIIKDLASENGGLPAGSTSLGILPVTLDTPTNRKYMSDANFDDWTPLSEVAEKLFEWSTNSDSRPTNGSLVKFETKSKVTTWTNL--", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::: ** ****: *. *::..: . *:*. ** :*. *. : * *: . * .:.. *:*:.:*.****:****. ..: *. . * . .: :: *: :.:: *: ***:.*:**..**: *.***.** :*.*.*:: :.*..::.*:*.*: ::.:******** *** *.:*:*. **** :. : .* ... **..***::. *.. * ", "identical_positions": 79, "similar_positions": 92, "identity": "32.24%" }, { "cls_id": "homologset.oma.827512", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9U1L2-1", "uniprot_id": "Q9U1L2_DROME", "id": "Q9U1L2-1", "name": "Ketoreductase domain-containing protein", "aln": "-----------------------------MSLSNKVVIVTGASSGIGAAIAQVLAREGATLALVGRNVANLEATKKSLKGTQAEIVVADVT------KDADAIVQQTLAKFGRIDVLVNNAGILG----KGGLIDLDIEEFDAVLNTNLRGVILLTKAVLPHLLKT--KGAVVNVSSCAGIRPFAGALSYGVSKAALDQFTKIVALEMAPQGVRVNSVNPGFVVTNIHR------NIGIVDEEYNGMLQRAINSHP--MGRVGDVTEVAEAVAFLASSKASFTTGALFPIDGGKHNLTPR---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9SCU0-1", "uniprot_id": "SDR2A_ARATH", "id": "Q9SCU0-1", "name": "Short-chain dehydrogenase reductase 2a", "aln": "MPAQVIAEQTTFHSVHDTIMEETNTTLYPKRLEGKVAIITGGAHGIGKATVMLFARHGATVVIADVDNVAGSSLAKSLSSHKTSPMVAFISCDVSVEADVENLVNVTVARYGRLDILFNNAGVLGDQKKHKSILDFDADEFDHVMRVNVRGVGLGMKHGARAMIKRGFKGCIISTASVAGVMGGMGPHAYTASKHAIVGLTKNAACELGKYGIRVNCISPFGVATSMLVNAWRKTSGGDVEDDDVEEMEEFVRSLANLKGETLRANDIAEAALYLASDESKYVNGHNLVVDGGVTTARNCVGL", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *..**.*:**.: *** * . ::**.***:.:.. : . .: ***.. ::. :** :: *.: :*: *:*::**:*:*.****:** : .::*:* :*** *:..*:*** * * ::* **.::..:* **: *. :* .** *: :** .* *:. *:***.:.* *.*.: . * *::: ::. :.* . *.. ..::***. :***.::.:..* : :*** . ", "identical_positions": 82, "similar_positions": 100, "identity": "27.06%" }, { "cls_id": "homologset.oma.827513", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q16698-1", "uniprot_id": "DECR_HUMAN", "id": "Q16698-1", "name": "2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial", "aln": "MKLPARVFFTLGSRLPCGLAPRRFFSYGTKILYQNTEALQSKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGGEEVLISGEFNDLRKVTKEQWDTIEELIRKTKGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A3Q1LNW7-1", "uniprot_id": "A0A3Q1LNW7_BOVIN", "id": "A0A3Q1LNW7-1", "name": "2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial", "aln": "-----SAILNQLVHLEV-LGSRTFFSYGTKTLYQNNEALQSKFFPPFPKVMLPANSFQGKVAFITGGGTGLGKGMTTCLSSLGAQCVIASRKIDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNAVSETIKVIGHPDIVINNAAGNFISPSERLSPNAWKTITDIVLNGTAFVTLAIGKELIKAQKGASFLAITTIYAETGSGFVVPSASAKAGVEALNKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGAFEKEMIDRIPCGRLGTVEELANLAAFLCSDYASWINGAVIRFDGGEEVLISGEFNSLRKVTKDQWDIIEGLIRKTKGS", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q64591-1", "uniprot_id": "DECR_RAT", "id": "Q64591-1", "name": "2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial", "aln": "MALLARAFFAGVSRLPCDPGPQRFFSFGTKTLYQSIDAPQSKFFPPILKPMLPPNAFQGKVAFITGGGTGLGKAMTTFLSSLGAQCVIASRNIDVLKATAEEITSKTGNKVYAIRCDVRDPDMVHNTVLELIKVAGHPDVVINNAAGNFISPSERLSPNGWKTITDIVLNGTAYVTIEIGKQLIKAQKGAAFLAITTIYAESGSGFVMPSSSAKSGVEAMNKSLAAEWGRYGMRFNIIQPGPIKTKGAFSRLDPTGKFEKDMIERIPCGRLGTVEELANLATFLCSDYASWINGAVIRFDGGEEVFLSGEFNSLKKVTKEEWDVIEGLIRKTKGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ62-1", "uniprot_id": "DECR_MOUSE", "id": "Q9CQ62-1", "name": "2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial", "aln": "MALLGRAFFAGVSRLPCDPGPQRFFSFGTKTLYQSKDAPQSKFFQPVLKPMLPPDAFQGKVAFITGGGTGLGKAMTTFLSTLGAQCVIASRNIDVLKATAEEISSKTGNKVHAIRCDVRDPDMVHNTVLELIKVAGHPDVVINNAAGNFISPSERLTPNGWKTITDIVLNGTAYVTLEIGKQLIKAQKGAAFLAITTIYAESGSGFVMPSSSAKSGVEAMNKSLAAEWGRYGMRFNIIQPGPIKTKGAFSRLDPTGRFEKEMIDRIPCGRLGTMEELANLATFLCSDYASWINGAVIRFDGGEEVFLSGEFNSLKKVTKEEWDIIEGLIRKTKGS", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: :* ..: ***:*** ***. :* ***** *. * ***.::*****************.*** **:**********::********:*:*:*****:**:*********:*:* * *** ***::************:***:**.*************:**: ***:********:**:*******:*****:**:***:****:.********:******:******************* ***:** *********:*******:***************:*******::*****.*:****::** ** ********", "identical_positions": 252, "similar_positions": 53, "identity": "75.22%" }, { "cls_id": "homologset.oma.827515", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VWP2-1", "uniprot_id": "Q9VWP2_DROME", "id": "Q9VWP2-1", "name": "Ketoreductase domain-containing protein", "aln": "---------MWTDLAGKVILVTGAGAGIGQALVKQLASAGATVIA--------VARKPEQLQQLVAFDPVH-----IQPLQLDLSGWQAVREGLAKVP-----LLDGLVNNAGVAIIKP--FEELTEQDFDTHFDVNIKAVFNVTQSLLPRLKDG---ASIVNVSSIASSRSFGGHTAYSATKAALDSLTKSLALELGPRKIRVNSVNPTVVLTKMGADNWSDPAKSGPLLAHIPLNRFCEVQEVVDATGYLLSSKSSFVNGHHILLEGGYSVS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "G3N1E7-1", "uniprot_id": "G3N1E7_BOVIN", "id": "G3N1E7-1", "name": "", "aln": "---------MQLNFSGLRALVTGAGKGIGRDTVKALYASGARVVA--------VSRTNADLVSLSKECPG------IEPVCVDLGDWKATEKALGGVG-----PVDLLVNNAAVALMRP--FLEVTKEDFDRSFSVNLRSAFQVSQIVARGMINRGVPGSIVNVSSMVAHVTFPNLAAYSTTKGAMTMLTKSMAMELGPYKIRVNSVNPTVVLTAMGQKVSADPEFSQKLKERHPLRKFAEVEDVVNSILFLLSDRSASTSGSGILVDAGYLAS", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q9SQR4-1", "uniprot_id": "ADRC3_ARATH", "id": "Q9SQR4-1", "name": "NADPH-dependent aldehyde reductase-like protein, chloroplastic", "aln": "MSTHSSISQPPLPLAGRVAIVTGSSRGIGRAIAIHLAELGARIVINYTSKAADAERVASEINDFPVREEITGKGPRAIVVQANVSEPSQVKSMFDAAESAFEAPVHILVNSAGILDPKYPTIADTSVEDFDHTFSVNTKGAFLCSKEAANRLKQGG-GGRIILLTSSQTRSLKPGFGAYAASKAAVETMVKILAKELKGTGITANCVAPGPIATEMFFDG-KTPELVEKIAAESPFGRVGEAKDVVPLVGFLAGDGGEWVNGQIIPVNGGYV--", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* :***:. ***: . * ** :: . * :: .: : ::. . ... : . :. ***.*.: : : : : :*** *.** :..* :: : : . *: ::* : . **:::*.*: :.* :* ** * .*.* * : * * . * : . *: :. *.::** :* .. . ..* * ::.** ", "identical_positions": 48, "similar_positions": 77, "identity": "17.52%" }, { "cls_id": "homologset.oma.827516", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P47727-1", "uniprot_id": "CBR1_RAT", "id": "P47727-1", "name": "Carbonyl reductase [NADPH] 1", "aln": "-----------------------MSSDRPVALVTGANKGIGFAIVRDLCRKFLGDVVLTARDESRGHEAVKQLQTEGLS-PRFHQLDIDNPQSIRALRDFLLQEYGGLNVLVNNAGIAFKVVDPTPFHIQAEVTMKTNFFGTQDVCKELLPIIK---PQGRVVNVSSSVSLRALKSCSPELQQKFRSETITEEELVGLMNKFIEDAKKGVHAKEGWPN--SAYGVTKIGVTVLSRIYARKLNEERREDKILLNACCPGWVRTDMAGPKATKSPEEGAETPVYLALLPPG--AEGPHGQFVQDKKVEPW-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9M198-1", "uniprot_id": "Q9M198_ARATH", "id": "Q9M198-1", "name": "", "aln": "MDVVTLMYGLITYIIYAYGIIHEWWSEETTAVVTGANKGIGFAVVKRLLELGL-TVVLTARNAENGSQAAESLRRIGFGNVHFCCLDISDPSSIAAFASWFGRNLGILDILVNNAAVSFNAVGEN-LIKEPETIIKTNFYGAKLLTEALLPLFRRSVSVSRILNMSSRLGT-LNKLRSPSIRRILESEDLTNEQIDATLTQFLQDVKSGTWEKQGWPENWPDYAISKLALNAYSRVLARRYDGK----KLSVNCLCPGFTRTSMTGGQGTHTADEAAAIVAKLVLLPPEKLATGKFYICVESKKLISKL", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:...*:***********:*: * . * ******: ..* :*.:.*: *:. :* ***.:*.** *: .:: :: * *::*****.::*:.*. . : :.*. :****:*:: : : ***::: . .*::*:** :. * **.::: :.** :*:*:: . :.:*::*.*.*. *:***: . *.::*:.:.. **: **: : : *: :*. ***:.**.*:* :.*::.:*.* . *.**** * * . *:.**: . ", "identical_positions": 99, "similar_positions": 112, "identity": "32.04%" }, { "cls_id": "homologset.oma.827518", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1SCT9-1", "uniprot_id": "F1SCT9_PIG", "id": "F1SCT9-1", "name": "Retinol dehydrogenase 14", "aln": "MAVA-TVAAFLAALGGALWLAARRFVGPSVQRLHRGGDSGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPNSGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFAVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVRPLFNLVSWAFFKTPAEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVARKLWDISEVMVGILK", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q17QW3-1", "uniprot_id": "RDH14_BOVIN", "id": "Q17QW3-1", "name": "Retinol dehydrogenase 14", "aln": "MAVG-TAAALLAALGGILWLAARRFVGSSVQRLHQGRDSGLMRGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRERAEEAAGQLRREVCPAGGPDSGPNSGGAGELVVKELDLASLSSVRSFCQEMLQEEPRLDVLINNAGVFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTSVTVNVLHPGIVRTNLGRHIHIPLLVRPLFNLVSWAFFKTPEEGAQTAVYLASSPEVEGVSGRYFGDCKEEELLPKAMDESVARKLWDISEVMVGILK", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q9HBH5-1", "uniprot_id": "RDH14_HUMAN", "id": "Q9HBH5-1", "name": "Retinol dehydrogenase 14", "aln": "MAVA-TAAAVLAALGGALWLAARRFVGPRVQRLRRGGDPGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPGVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPVEGAQTSIYLASSPEVEGVSGRYFGDCKEEELLPKAMDESVARKLWDISEVMVGLLK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9ERI6-1", "uniprot_id": "RDH14_MOUSE", "id": "Q9ERI6-1", "name": "Retinol dehydrogenase 14", "aln": "MAVASVAAALLAALGGALWLAARRFSGPRNQRQQGGGDPGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRQELCQAGGAGPD---GTDGQLVVKELDLASLRSVRAFCQELLQEEPRLDVLINNAGVFHCPYTKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGEINFEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLARPLFNLVSWAFFKTPLEGAQTSIYLACSPDVEGVSGRYFGDCKEEELLPKAMDESVARKLWDISEVMVGILK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZUY0-1", "uniprot_id": "D3ZUY0_RAT", "id": "D3ZUY0-1", "name": "Retinol dehydrogenase 14", "aln": "MAVASVAAALLAALGGALWLAARRFSGSSGQRRQGGGDPGLMHGKTVLITGANSGLGRATAGELLRLGARVIMGCRDRARAEEAAGQLRQELGQAGGLGPD---ATDGQLVVKELDLASLRSVRAFCQELLQEEPRLDVLINNAGVFQCPYTKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFEDLNSEQSYNKSFCYSRSKLANILFTRELAHRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLARPLFNLVSWAFFKTPLEGAQTSIYLASSPDVEGVSGRYFGDCKEEELLPKAMDESVARKLWDISEVMVGILK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8C2N5B7-1", "uniprot_id": "A0A8C2N5B7_CRIGR", "id": "A0A8C2N5B7-1", "name": "Retinol dehydrogenase 14", "aln": "MAVATVAAALLAALGGALWLATRRFSGARGQRMQGGGDRSLMHGKTVLITGANSGLGRATASELLRLGARVIMGCRDRARAEEAAGQLRQELGRAAGQEPN---ATEGQLVVKELDLASLRSVRAFCQELLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFEDLNSEQSYNKSFSYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLARPLFNLVSWAFFKTPQEGAQTSIYLASSPEVEGVSGRYFGDCKEEDLLPKAMDESVARKLWDISEVMVGILK", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***. ..**.****** ****:*** *. ** : * * .**:******************.**************** **********:*: : . *:*:*:******* ***:****:***************:*:*** **********.************************************:***:************.****************:*****.************************.:************** *****::***.**:******:********:*******:***************:**", "identical_positions": 274, "similar_positions": 37, "identity": "81.31%" }, { "cls_id": "homologset.oma.827525", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TQA3-1", "uniprot_id": "RDHE2_MOUSE", "id": "Q7TQA3-1", "name": "Epidermal retinol dehydrogenase 2", "aln": "MSQNLESVKNLLVFLGKSLLSVLEALLFHVISKPRKNVAGEIVLITGAGSGLGRLLALQFARLGAVLVLWDVNKEANDETHQLAREAGAARVHAYTCDCSRREEVYRVADQVKKEVGDVSILINNAGIVTGRNFLDCPDDLMEKSFDVNFKAHLWMYKAFLPAMIANNHGHLVCISSSAGLIGVNGLSDYCASKFAALGFAESMFIETLAKKQWGIKTTIVCPFFIKTGMFEGCTTKCPTLLPILDPEYAVRKIIDAILQEQLYLYMPKFLYFIVFLKSILPIKTGILIADYLGVFHMTEGFTGQKKKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZS85-1", "uniprot_id": "D3ZS85_RAT", "id": "D3ZS85-1", "name": "", "aln": "MPCNLESAKDLLVFLGKSLLSILEALLSHVISKPRKNVAGEVVLITGAGSGLGRLLALQFARLGSVLVLWDVNKETNEETRQIAQEAGAIRVHAYTCDCSQREEVYRVADQVKKEVGDVSILINNAGIVTGRKFLDCPDDLMEKSLDVNFKAHLWMYKAFLPAMIANNHGHLVCISSSAGLIGVNGLSDYCASKFAALGFAESMFVETLAQKQRGIKTTIVCPFFIKTGMFEGCTTKCPNLLPILDPEYAVRKIVDAILQEQLYLYMPKFLYFIMFLKSFLPIKTGILIADYLGLFHVMDGFTGQKKKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N3Y7-1", "uniprot_id": "RDHE2_HUMAN", "id": "Q8N3Y7-1", "name": "Epidermal retinol dehydrogenase 2", "aln": "MSFNLQSSKKLFIFLGKSLFSLLEAMIFALLPKPRKNVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYTCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGIKTTIVCPFFIKTGMFEGCTTGCPSLLPILEPKYAVEKIVEAILQEKMYLYMPKLLYFMMFLKSFLPLKTGLLIADYLGILHAMDGFVDQKKKL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. **:* *.*::******:*:***:: ::.*********:**********************:******:*** *:** ::*:**** **********::* ***************************::******:*****:********* ***********:************* *****:*********:*****:*:**:.:** ********************** **.*****:*:***.**::*****::******:***::****:**:***:*******::* :**..**** ", "identical_positions": 242, "similar_positions": 52, "identity": "78.32%" }, { "cls_id": "homologset.oma.827528", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q99L04-1", "uniprot_id": "DHRS1_MOUSE", "id": "Q99L04-1", "name": "Dehydrogenase/reductase SDR family member 1", "aln": "MVAPMKGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRATAQEAQSLGGRCVPVVCDSSQESEVKSLFEQVDREQKGRLDVLVNNAYAGVQAILNTTNKSFWEVPASIWDDINNVGLRGHYLCSVYGARLMVPAGKGLIVIVSSPGGLQHMFNVPYGVGKAACDRLAADCAHELRRHGVSYVSLWPGLVQTEMVKEFMAKEDTPEDPLFKKMKPDFSSAESPEMSGKCVVALATDPNILNLSGKVLPSCDLARRYGLKDIDGRPVKDYFSLGYALSQVSSLGWLNSFLPGFLRVPKWVVTLYNSKF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3HDD0-1", "uniprot_id": "G3HDD0_CRIGR", "id": "G3HDD0-1", "name": "", "aln": "MAVPMKGQVCVVTGASRGIGRGIALQLCKAGATVYITGRNLDTLRATAQEAQSLGGRCVPVVCDSSQESEVKSLFEQVDREQQGRLDVLVNNAFAGVQTILSTINKPFWEVPASIWDDINNVGLRGHYLCSVYGARLMVPAGKGLIVVVSSPGGLQHMFNVPYGVGKTACDRLAADCAHELRCHGVSYVSLWPGLVQTELVKEFMAKEDQPEDSLFKKAKPNFSKAESPEMSGKCVVALATDPKILSLSGKVLPSCDLARRYGLQDVDGRPVQDYFSLGYALSHVSSLGWLTSYLPGFLRVPKWIVTLYTSKF", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q6AXY8-1", "uniprot_id": "Q6AXY8_RAT", "id": "Q6AXY8-1", "name": "Dehydrogenase/reductase SDR family member 1", "aln": "MIMTMKGQVCVVTGASRGIGRGIALQLCQAGATVYITGRHLDTLRATAQEAQSLGGRCVPVVCDSSQESEVKSLFEQVDREQQGRLDVLVNNAYAGVQAILNTTTKSFWEAPASLWDDINNVGLRGHYLCSVYGARLMVPAGKGLIVVVSSPGGLQHMFNVPYGVGKAACDKLAADCAHELRRHGVSYVSLWPGLVQTEMVKEYVAKEEQPEDPLFKKMKSVLSSAETTEMSGKCVVALATDPNILSLSGKVLPSCDLARRYGLKDVDGRPVQDYFSLGYALSQVSSLRWLASYLPGFLRVPKWIVTLYTSKF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1SGQ0-1", "uniprot_id": "F1SGQ0_PIG", "id": "F1SGQ0-1", "name": "", "aln": "MVAPMQGQVCVVTGASRGIGRGIALQLCEAGATVYITGRHLDTLQVTAQEAQSRGGRCVPVVCDSSQESEVQSLFQQVAREQQGRLDVLVNNAYAGVQAIINNRKKAFWESPASVWDDVNNVGLRGHYLCSVYAARLMVPAGRGLIVIISSIGGLQYLFSVPYGVGKAACDRLAADCAQELRRHGVSYVSLWPGLVQTETLKEYMIKADTADDHMIEQIKLPFSSAETTEMSGKCVVALATDPNILSLSGKVLPSCDLARRYGLRDVDGRPVQDYLSVSSVLSHIPSLSWMASFLPSFLRMPKWLMTLYTSKF", "tax_id": 9823, "tax_name": "Pig" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .*:**********************:**********:****:.******* *****************:***:** ***:**********:****:*:.. .*.*** ***:***:**************.********:****::** ****::*.*******:***:******:*** **************** :**:: * : .:* :::: * :*.**:.**************:**.*****************:*:*****:**:*:. .**::.** *: *:**.***:***::***.***", "identical_positions": 233, "similar_positions": 61, "identity": "74.44%" }, { "cls_id": "homologset.oma.827530", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P70385-1", "uniprot_id": "DHB3_MOUSE", "id": "P70385-1", "name": "17-beta-hydroxysteroid dehydrogenase type 3", "aln": "----MEKLFIAAGLFVGLVCLVKCMRFSQHLFLRFCKALPSSFLRSMGQWAVITGAGDGIGKAYSFELARHGLNVVLISRTLEKLQTIAEEIERTTGSCVKIVQADFTREDIYDHIKEHLEGLEIGILVNNVGMLPSFFPSHFLSTSGESQ---NLIHCNITSVVKMTQLVLKHMESRRKGLILNISSGAALRPWPLYSLYSASKAFVYTFSKALSVEYRDKGIIIQVLTPYSISTPMTKYLNN-KMTKTADEFVKESLKYVTIGAESCGCLAHEIIAIILNRIPSRIFYSSTAQRFLLTRYSDYLKRNISNR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O54939-1", "uniprot_id": "DHB3_RAT", "id": "O54939-1", "name": "17-beta-hydroxysteroid dehydrogenase type 3", "aln": "----MEQFLLSVGLLVCLVCLVKCVRFSRYLFLSFCKALPGSFLRSMGQWAVITGAGDGIGKAYSFELARHGLNVVLISRTLEKLQVISEEIERTTGSRVKVVQADFTREDIYDHIEEQLKGLEIGVLVNNVGMLPNLLPSHFLSTSGESQ---SVIHCNITSVVKMTQLVLKHMESRRRGLILNISSGVGVRPWPLYSLYSASKAFVCTFSKALNVEYRDKGIIIQVLTPYSVSTPMTKYLNTSRVTKTADEFVKESLKYVTIGAETCGCLAHEILAIILNLIPSRIFYSSTTQRFLLKQFSDYLKSNISNR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F6RUH3-1", "uniprot_id": "F6RUH3_BOVIN", "id": "F6RUH3-1", "name": "17beta-estradiol 17-dehydrogenase", "aln": "MKEALEQFFIFVGLLVCLVYLMKCVRFSKCIFLHFWKVLPRSFLKSVGEWAVITGAGDGIGKAYSFELARQGFNVVLISRTLEKLQAIAAEIELTIGSTVKIIQADFAKDDIYDYIKEKLKGLEIGILVNNVGMLPNLLPSHFLNTSDDIQ---SLIHCNITSVVKMTQLILKHMESRQKGLILNISSGVALFPWPLYSMYSASKAFVCTFSKALQAEYKDKGIIIQVLTPYAISTPMTKYLSTNMITKTADEFVKESLNYVTIGDETCGCLTHEILAVILSLIPSWAFYSSVFQKMLLTRYVDYLKKNANIR", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1S4L6-1", "uniprot_id": "F1S4L6_PIG", "id": "F1S4L6-1", "name": "17beta-estradiol 17-dehydrogenase", "aln": "MGDILGQFFIFVGLLVCLVYLAKCVRFCKCIFLNFWRVSPRSFLMSMGQWAVITGAGDGIGKAYSFELARQGLNVVLISRTLEKLQTIAAEIEWTIGTSVKIIQADFTKDDIYEDIKEKLKGLEIGILVNNVGMLPNLLPSHFLNTPDNIQ---SVIHCNITSVVKMTQLILKHMESRQKGLILNISSGVALFPWPLYSMYSSSKAFVCTFSKALQAEYEAKGIIIQVLTPHAVSTQMTNYLNTNMITKTADEFVKESLKYVTIGDETCGCLAHEILAIILSLIPSRVFYSSTFQKMVLTHYVKYLKQNFNLR", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "P37058-1", "uniprot_id": "DHB3_HUMAN", "id": "P37058-1", "name": "17-beta-hydroxysteroid dehydrogenase type 3", "aln": "MGDVLEQFFILTGLLVCLACLAKCVRFSRCVLLNYWKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKEKLAGLEIGILVNNVGMLPNLLPSHFLNAPDEIQ---SLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAMTKYLNTNVITKTADEFVKESLNYVTIGGETCGCLAHEILAGFLSLIPAWAFYSGAFQRLLLTHYVAYLKLNTKVR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6QA32-1", "uniprot_id": "DHB3_DANRE", "id": "Q6QA32-1", "name": "17-beta-hydroxysteroid dehydrogenase type 3", "aln": "-MTLTEIIFVLTGTCAILVFGGKIASLIMMLITKLFCPLPEAFFTSLGKWAVITGGSDGIGRAYAEELSKQGMSVIIISRNQEKLDRAAKKIELNTGGKVKVIAADFTKDDIYGHITENIEGLDIGVLVNNVGILPSQIPCKLLETSDLEERIYDIVNCNVKSMVKMCRIVLPGMQQRRRGVILNVSSGIAKIPCPIYTLYAASKVFVERFSQGLQAEYISKGIIIQTVAPFGVSTAMTGHQKPDMVTFTAEEFVRSSLKYLKTGDQTYGSITHTLLGRIVQSIPTWVLQSETFQ----HHFQEYVK-NRDRR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: .* . *. * : :: * :*: *:*:******..****:**: **:::*:.*::***. ***: : :** . * **:: ***:::*** * *:: **:**:******:**. :*.::*.:.. : .:::**:.*:*** :::* *:.*::*:***:*** . * *:*::*::**.** **:.*. ** * :***.::*..:** ** : . :* **:***:.**:*:. * :: *.::* ::. ::. **: : * . * :: *:* * . *", "identical_positions": 114, "similar_positions": 109, "identity": "36.42%" }, { "cls_id": "homologset.oma.827532", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "E7F258-1", "uniprot_id": "E7F258_DANRE", "id": "E7F258-1", "name": "15-hydroxyprostaglandin dehydrogenase [NAD(+)]", "aln": "MSLHGKTALVTGGAQGIGRAVVEELLQNGAKVALVDLNQSVGEECKSDLDDQFGEDNCIFIQCDVTDGEKLGDAFRNTVDRFGRLDIVINNAGINNEKNWEKTIEVNLTSVIKGTYLALEHMSKEYGKQGGAIINVSSMAAFLHSPHQPVYTATKYGVIGFSRAMADASEQGNYGVRINALCPAFVDTQLLQTVEHEETMGKFVKYKDDFKQRMDKYGVLKPSLIAEGMLRLITDESLNGAVMKITCSKGIHFHTY--EPLSA--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1C688-1", "uniprot_id": "E1C688_CHICK", "id": "E1C688-1", "name": "15-hydroxyprostaglandin dehydrogenase [NAD(+)]", "aln": "MHVNGKVALVTGGAQGIGRAFVQALLGKGAKVALLDRNPEAGQQSKAALDEQFEAQRTVFIQCDVTDTEQLKGAFKKVIEHFGRLDIVVNNAGVNNEKDWESTIQINLTSVIRGTYLGLEYMRKGNGGDGGVIINISSLAGLMPAAFQPVYCATKHGVIGFTRSIALAANMENYGVRLNTICPGFVNTPILQSIDKEENMGQYYSYKDEIKNMMQFYGVMDPSIIAEGLITIIEDDTLNGEVMKITASQGIHFQEYSQTPYTSKR", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::**.*************.*: ** :******:* * ..*::.*: **:** :. :******** *:* .**::.:::*******:****:****:**.**::******:****.**:* * * :**.***:**:*.:: :..**** ***:*****:*::* *:: *****:*::**.**:* :**::::**.**:: .***::*: *: ***:.**:****:: :* *::*** *****.*:****: * * :: ", "identical_positions": 150, "similar_positions": 81, "identity": "56.6%" }, { "cls_id": "homologset.oma.827533", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q80XN0-1", "uniprot_id": "BDH_MOUSE", "id": "Q80XN0-1", "name": "D-beta-hydroxybutyrate dehydrogenase, mitochondrial", "aln": "---MLAARLSRPLSQLPGKALSVRDRENGTRHTLLFYPASFSPDTRRTYASQADAASGKAILITGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGDAGVKELDSLKSDRLRTIQLNVCNSEEVEKAVETIRSGLKDPEKGMWGLVNNAGISTFGEVEFTSMETYKEVAEVNLWGTVRTTKSFLPLLRRAKGRVVNISSMLGRMANPARSPYCITKFGIEAFSDCLRYEMHPLGVKVSVVEPGNFIAATSLYSPERIQAIAKKMWDDLPEVVRKDYGRKYFDEKIAKMETYCNSGSTDTSSVINAVTHALTAATPYTRYHPMDYYWWLRMQIMTHFPGAISDKIYIH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29147-1", "uniprot_id": "BDH_RAT", "id": "P29147-1", "name": "D-beta-hydroxybutyrate dehydrogenase, mitochondrial", "aln": "---MLAARLSRPLSQLPGKALSVCDRENGTRHTLLFYPASFSPDTRRTYTSQADAASGKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLLKDKGDAGVRELDSLKSDRLRTIQLNVCNSEEVEKAVETVRSGLKDPEKGMWGLVNNAGISTFGEVEFTSMETYKEVAEVNLWGTVRTTKSFLPLLRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMHPLGVKVSVVEPGNFIAATSLYSPERIQAIAKKMWDELPEVVRKDYGKKYFDEKIAKMETYCNSGSTDTSSVINAVTHALTAATPYTRYHPMDYYWWLRMQVMTHFPGAISDKIYIH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3GSJ7-1", "uniprot_id": "G3GSJ7_CRIGR", "id": "G3GSJ7-1", "name": "D-beta-hydroxybutyrate dehydrogenase, mitochondrial", "aln": "--MMLAARLSRPLSQLPGKTLSVCSRENGARHT-LFYPASFTASIQRTYASEANEASGKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGDAGVKELDSLKSDRLRTIQLNVCNDEEIEKAVETVRSSLEDPEKGMWGLVNNAGISTFGEVEFTSMATYKEVAEVNLWGTVRTTKSFLPLLRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMHPLGVKVSVVEPGNFIAATSLYSPERIQAIAKKMWDELPEVVRKDYGKKYFDEKIAKMETYCNSGSTDTSSVIDAVTHALTAATPYTRYHPMDYYWWLRMQIMTHFPGAISDMIYIH", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q02338-1", "uniprot_id": "BDH_HUMAN", "id": "Q02338-1", "name": "D-beta-hydroxybutyrate dehydrogenase, mitochondrial", "aln": "---MLATRLSRPLSRLPGKTLSACDRENGARRPLLLGSTSFIPIGRRTYASAAEPVGSKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTPYTRYHPMDYYWWLRMQIMTHLPGAISDMIYIR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1SQX8-1", "uniprot_id": "F1SQX8_PIG", "id": "F1SQX8-1", "name": "D-beta-hydroxybutyrate dehydrogenase, mitochondrial", "aln": "MATMLTARLSRPLSQLPRKTLNFSERENGARGSLLFYSPSFVPGSRRTYADSVNPVGSKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLKSDRLRTVQLNVCKSEEVEKVVETIRSSLQDPEKGLWGLVNNAGISTFGDVEFTSMETYKEVAEVNLWGTVRVTKSFLPLIRRAKGRVVNISSIMGRLANVSRSPYCITKFGVEAFSDCLRYEMHPLGVKVSVVEPGNFIVATSLYSPERIRAIATKMWEQVPEAVRQDYGRKYFDEMVARMENFCNSGSTDTSPVINAVTHALTSTTPYTRYHPMDYYWWVRMQIMTHLPGAISDRIYIH", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A8V0YU17-1", "uniprot_id": "A0A8V0YU17_CHICK", "id": "A0A8V0YU17-1", "name": "D-beta-hydroxybutyrate dehydrogenase, mitochondrial", "aln": "---MLATKLSRPLLNLPVKTLTVKNPGNSFRPVQRFCFPVLSSCGSRSYASEVDQIGSRAVLITGCDSGFGFALAKHLHTKGFIIYAGCLQKNKGEGGSKDLDNMNSDRMRTVQLNVCDSKEVDRAVEHVNSSLEDPEKGLWGLVNNAGISTFGEVEFTSMDTYMEVAEVNLWGTVRTTKAFLPLIRRSKGRVVNISSMMGRMGSPARSPYCITKFGVEAFSDCLRYEMQPQGVMVSIVEPGNFIAATNLYSPERIKAIADKMWDELPEIVRKDYGRKYFDEQVSKMETYCNSGSTDTSPVIESVAHALTSTAPYTRYHPMDYYWWLRMQIMTHMPAAISDRLYVY", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:::***** .** *:*. . *. * : . : . *:*:. .: ..:*:*:*********:******:***:::**** *:**. * ::**.::***:**:*****..:*:::.** :.*.*:*****:*************:*****: ** :*********** **:****:**:*********::**:.. :**********:*********** * ** **:*******.**.***** *:*** ***:::** **:***:***** :::**.:*.*******.**::*:****:::*************:***:***:*.**** :*: ", "identical_positions": 216, "similar_positions": 89, "identity": "62.43%" }, { "cls_id": "homologset.oma.827536", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q96NR8-1", "uniprot_id": "RDH12_HUMAN", "id": "Q96NR8-1", "name": "Retinol dehydrogenase 12", "aln": "MLVTLGLLTSFFSFLYMVAPSIRKFFAGGVCRTNVQLPGKVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTKNSQVLVRKLDLSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTADGFETHLGVNHLGHFLLTYLLLERLKVSAPARVVNVSSVAHHIGKIPFHDLQSEKRYSRGFAYCHSKLANVLFTRELAKRLQGTGVTTYAVHPGVVRSELVRHSSLLCLLWRLFSPFVKTAREGAQTSLHCALAEGLEPLSGKYFSDCKRTWVSPRARNNKTAERLWNVSCELLGIRWE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1SA23-1", "uniprot_id": "F1SA23_PIG", "id": "F1SA23-1", "name": "NADP-retinol dehydrogenase", "aln": "MLAVLGLLTSFLFFLYVTAPSIRKFFAGGVCRTNMQLPGKVVVITGANTGIGKETARELARRGARVYIACRDVLKGESAASEIRADTKNSQVLVRKLDLSDTKSIRAFAEGFLTEEKQLHILINNAGVMLCPYSKTADGFETHLGVNHLGHFLLTHLLLEQLKASAPARVVNLSSVVHHAGKIRFHDLQGEKHYNRGFAYCHSKLANVLFTRELAKRLQGTGVTTYAVHPGIVQSELVRHSFLLCLLWRLFSRFLKTAREGAQTSLHCALAEGLEPLSGKYFSDCKRAWVSPRARNNKTAERLWNVSCELLGIQWE", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q8BYK4-1", "uniprot_id": "RDH12_MOUSE", "id": "Q8BYK4-1", "name": "Retinol dehydrogenase 12", "aln": "MLFILVLLTSFLSILYLTAPSIRKFFAGGVCTTNVQIPGKVVVITGANTGIGKETARELARRGARVYIACRDVLKGESAASEIRADTKNSQVLVRKLDLSDTKSIRAFAERFLAEEKKLHILINNAGVMMCPYSKTTDGFETHFGVNHLGHFLLTYLLLERLKESAPARVVNLSSIAHLIGKIRFHDLQGQKRYCSAFAYGHSKLANLLFTRELAKRLQGTGVTAYAVHPGVVLSEITRNSYLLCLLWRLFSPFFKSTSQGAQTSLHCALAEDLEPLSGKYFSDCKRMWVSSRARNKKTAERLWNVSCELLGIQWE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZEP9-1", "uniprot_id": "D3ZEP9_RAT", "id": "D3ZEP9-1", "name": "NADP-retinol dehydrogenase", "aln": "MLVILVLLTSFFSILYLATPSIRKFFAGGVCTTKVQIPGKVVVITGANTGIGKETARELARRGARVYIACRDVLKGESAASEIRADTKNSQVLVRKLDLSDTKSIRTFAEGFLAEEKKLHILINNAGVMMCPYSKTVDGFETHFGVNHLGHFLLTYLLLGRLKESAPARVINLSSVAHLGGKIRFHDLQSKKRYCSGFAYSHSKLANVLFTRELAKRLQGTGVTAYVVHPGCVLSEITRHSFLMCLLWRLFSPFFKSPWQGAQTSLHCALEEGLEPLSGKYFSDCKRTWVSPRARNKKTAERLWNVSCELLGIQWE", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * *****: :**:.:************ *::*:*********************** ***********************.*********************:*** **:***:***********:******.******:***********:*** :** ******:*:**:.* *** *****.:*:* .*** ******:****************:*.**** * **:.*:* *:******** *.*:. :********** *.************** ***.****:****************:**", "identical_positions": 254, "similar_positions": 40, "identity": "80.38%" }, { "cls_id": "homologset.oma.827538", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5SS80-1", "uniprot_id": "DHR13_MOUSE", "id": "Q5SS80-1", "name": "Dehydrogenase/reductase SDR family member 13", "aln": "MEMLLLGAGLLLGAYVLVYYNLVKAPSCGG-IGSLRGRTVVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNE-VIFMALDLASLASVQAFATAFLSSEPRLDVLIHNAGISSCGRTR-ETFNLLLRVNHVGPFLLTHLLLPRLRSCAPSRVVIVSSAAHRRG-RLDFTRLDCPVVGWQQELRAYADSKLANVLFARELATQLEGTG--VTCYAAHPGPVNSELFLRHLPGWLRPILRP-LAWLVLRAPQGGAQTPLYCALQEGIEPLSG-RYFANCHVEEVSPAARDDQAAQRLWKATKKLAGLAPGDDDDDPDEEPEPEDPRAPSSQSAPSPEKTTVSGPSHSYQGSQDLSKLTQRRIQVKDEPTP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A9J7GD64-1", "uniprot_id": "A0A9J7GD64_CRIGR", "id": "A0A9J7GD64-1", "name": "Dehydrogenase/reductase SDR family member 13", "aln": "METLLLGAGLLLGAYVLVYYNLVKAPPCGG-IGSLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAVFDLRQESGNNE-VIFMALDLASLASVQAFATAFLSSEPRLDILIHNAGISSCGRTR-ETFNLLLRVNHVGPFLLTHLLLPRLKSCAPSRVVVVSSAAHRRG-RLDFTRLDCPVVGWQQELRAYADSKLANVLFARELANQLEGTG--VTCYAAHPGPVNSELFLRHLPGWLCPILRP-LAWLLLRAPQGGAQTPLYCALQEGIEPLSG-RYFANCRVEEVSPAARDDQAAHRLWKATKKLAGLGPGEDDDDPEEEPQPQGPRALSSLSAPYPEKTTVSGLSHSCPGSPDLSKLTQRRIQMKARPLPD--", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "F1RNA5-1", "uniprot_id": "F1RNA5_PIG", "id": "F1RNA5-1", "name": "Dehydrogenase/reductase SDR family member 13", "aln": "MEALLLGVGLLLGAYVLVYYNLVKAPPCRG-IASLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNE-VIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTR-EPFNLLLRVNHVGPFLLTHLLLPRLKTCAPSRVVVVSSAAHRRG-RLDFTRLDRPVVGWRQELRAYADSKLANVLFTRELATQLEGTG--VTCYAAHPGPVNSELFLRHVPRWLRPLLCP-LAWLVLRAPRGGAQTPLYCALQEGIEPLSG-RYFANCHVEEVPPAARDDRAAHRLWEASKRLAGLEPGEDAE-SDEEPQPVDPGVPSSLSSPHPEEPAASEPYTSPQSSPDLSKVTRR-IPVKAEPEPQAS", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q17QU7-1", "uniprot_id": "DHR13_BOVIN", "id": "Q17QU7-1", "name": "Dehydrogenase/reductase SDR family member 13", "aln": "MEALLLGVGLLLGAYVLVYYNLVKAPPCRG-LASLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNE-VIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTR-EPFNLLLRVNHIGPFLLTHLLLPRLKTSAPSRVVVVSSAAHRRG-RLDFTRLDHPVVGWQQELRAYANSKLANVLFARELATQLEGTG--VTCYAAHPGPVNSELFLRHVPGWLRPLLRP-LAWLVLRAPRGGAQTPLYCALQEGIEPLSG-RYFANCHVEEVPPAARDDRAAHRLWEASRKLAGLGPGEDAE-SDEDSQPEDPGTPSSPSSPHPEEPTVSELYPSPQSSTDRSTVTCR-IPVKAELEPQAC", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q6UX07-1", "uniprot_id": "DHR13_HUMAN", "id": "Q6UX07-1", "name": "Dehydrogenase/reductase SDR family member 13", "aln": "MEALLLGAGLLLGAYVLVYYNLVKAPPCGG-MGNLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFDLRQESGNNE-VIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTR-EAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCRG-RLDFKRLDRPVVGWRQELRAYADTKLANVLFARELANQLEATG--VTCYAAHPGPVNSELFLRHVPGWLRPLLRP-LAWLVLRAPRGGAQTPLYCALQEGIEPLSG-RYFANCHVEEVPPAARDDRAAHRLWEASKRLAGLGPGEDAE-PDEDPQSEDSEAPSSLSTPHPEEPTVSQPYPSPQSSPDLSKMTHR-IQAKVEPEIQLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q54I93-1", "uniprot_id": "Q54I93_DICDI", "id": "Q54I93-1", "name": "Short-chain dehydrogenase/reductase family protein", "aln": "-------MGLDENEIINNDCNIGNDNNNNSNIILNRQLVVIVTGSSDGLGKVVSGMLAKTNYFVILANRDLIKAKLVLDEILSTTPNNKNVISMKLDLSSFDSIKEFVNQFEKLNLQLDVLINNAGIYTPPFSLPEGFESQLMVNHLGPFLLTNLLIN--KFTENARIINLSSIAHKNSEIFNVEDLSCKSIDSYNAIKRYSNSKLYAILFTKELNRIFKKNNSKIIALSLHPGVISTTNLFKNIPNYIKLLLTISKPFTTTINTASTAIYRLAVGADPELPLLTGGEYFNINVLVDPIPQALSQENWRLLWAKSCEYCKIDDIGK-------------------------------------------------------------", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** . : *: : . : * ..:***:..*:**:.: **: . *:** *. :.: . :: . : **: ** * ***:*: *:: *.. * . : :**:**:**** : : * *: * ***:******:**: : :*:: ::* ** .. ::. *. :. : :: *:::** :**::** :: .. : . : *** :.: :::::* :: :* .: . . * * . : : *:* .** : : * * .:. : ** : . . : . ", "identical_positions": 77, "similar_positions": 107, "identity": "19.9%" }, { "cls_id": "homologset.oma.827540", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BTX9-1", "uniprot_id": "HSDL1_MOUSE", "id": "Q8BTX9-1", "name": "Inactive hydroxysteroid dehydrogenase-like protein 1", "aln": "MAAVDSFYLLYREIARSCNCYMEALALVGAWYTARKSITVICDFYSLVRLHFIPRLGSRPDLIKQYGRWAVISGATDGIGKAYAEELASHGLNVILISQEEEKLQAAAKHIADTYRVETLVLVADFSRGREIYAPIREALRDRDIGILVNDVGAFYPYPQYFSQVPEDTLWDIVNVNIAAASLMVHIVLPGMVERKKGAIVTVSSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVTSSGAAPASFLHRCPWLAPSPRVYAQHAVSTLGISKRTTGYWSHSIQFLFAQYMPEWLWVWGANLLNR--SLRKEALSCQA-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V8B7-1", "uniprot_id": "HSDL1_RAT", "id": "Q4V8B7-1", "name": "Inactive hydroxysteroid dehydrogenase-like protein 1", "aln": "MAAVDSFYLLYREIARSCSCYVEALALVGAWYTARKSIPVICDFYSLVRLHFIPRLGSRPDLIKQYGRWAVISGATDGIGKAYAEELASHGLNIILISQEEEKLQAVAKHIADTYRVETLVLVADFSRGREIYAPIREALRDRDIGILVNDVGAFYPYPQYFSQVPEDTIWDIVNVNIAAASLMVHIVLPGMVERKKGAIVTVSSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVTSSVTAPGSFLRRCPWLAPSPRVYAQHAVSTLGISKRTTGYWSHSIQFLFAQYMPEWLWVWGANLLNR--SLRKEALSSQA-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A9J7FRG6-1", "uniprot_id": "A0A9J7FRG6_CRIGR", "id": "A0A9J7FRG6-1", "name": "Inactive hydroxysteroid dehydrogenase-like protein 1", "aln": "MAAVDSFYLLYREIARSCNCYMEALALVGAWYTARKSITVICDFYSLIRLHFIPRLGSRPDLIKQYGRWAVVSGATDGIGKAYAEELACHGLNIILISQEEEKLQAVAKNIADTYRVETVVMVADFSRGREIYAPIREALRDRDIGILVNDVGAFYPHPQYFAQLPEDTLWDIVNVNIAAASLMVHIVLPGMVERKKGAIITVSSGSCCKPTPHLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSVTAPGSFLHRCPWLAPSPRVYAQHAVSTLGISKRTTGYWSHSIQTAAREPALDWYSCSSSLEFGETCSVRSSCSSSLELVCFT", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q3SXM5-1", "uniprot_id": "HSDL1_HUMAN", "id": "Q3SXM5-1", "name": "Inactive hydroxysteroid dehydrogenase-like protein 1", "aln": "MAAVDSFYLLYREIARSCNCYMEALALVGAWYTARKSITVICDFYSLIRLHFIPRLGSRADLIKQYGRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSMTAPSNFLHRCSWLVPSPKVYAHHAVSTLGISKRTTGYWSHSIQFLFAQYMPEWLWVWGANILNR--SLRKEALSCTA-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PJF6-1", "uniprot_id": "HSDL1_BOVIN", "id": "A5PJF6-1", "name": "Inactive hydroxysteroid dehydrogenase-like protein 1", "aln": "MAAVDSFYLLYREIARSCNCYIEALALVGAWYTARKSITVVCDFYSLIRLHFIPRLVSRADLIKQYGRWAVVSGATDGIGRAYAEELASRGLNIVLISRSQEKLQMVAKDIADTYKVETDIIVADFSSGREIYDMIREALQDRDIGILVNNVGVFYPYPQYFTQVSEDTLWDIVNVNIAAASLMVHIVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATNVATPGSFLHKCPWLVPSPKVYAHHAVSTLGISKRTTGYWSHSIQFLFAQYMPEWLWVWGANILNR--SLRKEALSCKA-----", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A5WWC6-1", "uniprot_id": "HSDL1_DANRE", "id": "A5WWC6-1", "name": "Inactive hydroxysteroid dehydrogenase-like protein 1", "aln": "MAAVDSFQLLYREIARSCSGYVETLALVGACYMASKTVIFMRDCYSLIRLYFVPRLVRHRDLSQQYGQWAIICGASEAIAKAYAEELARHGICVILISKDLSSVSDTARLISNNYGVEAICIEADFNQGPSACKPIKDAISSKDIGFLVNSFDGTLEISQNFLELSESVLWGTINRNIAATTLVTRLALPAMMEKGRGAVVNISSGHCFHPIPRKAAFSASTAFLDNFSRSLHYEYGDQGVFVQSLLPFRVAS--QRPEGSAPPASWLVPSPQVYASHALSTLGISHRTTGYWPHSMQLGLVKMMPEWVWMLGS---------RVFTMAT-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******* **********. *:*:****** * * *:: .: * ***:**:*:*** : ** :***:**::.**::.*.:******* :*: ::***:. ..:. .*: *::.* **: : ***. * . *::*: .:*:*:***... .* * ::.*. :*. :* ****::*:.::.**.*:*: :**::.:*** * :* *: ******.*:**:***:*:***..:*:*****:** *:: * . ..**.***:*** **:******:******.**:* : :* .: * : ", "identical_positions": 150, "similar_positions": 101, "identity": "44.51%" }, { "cls_id": "homologset.oma.827547", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B8A5W4-1", "uniprot_id": "DHRSX_DANRE", "id": "B8A5W4-1", "name": "Polyprenol dehydrogenase", "aln": "MWRLLHCILGFIRLYLDGVKVLLYQLFNKS---FRLPDLPEQNGKVAIVTGGTRGMGYEISRHLVSLDMHVIIAGNEEEEGLAAVKKIQEELNQGKVEFMYLDLASLTSVRQFVQRYNAKGLPLHVLVNNAGVMLVPERRTEDGFELHFGLNYLGHFLLTNLLLGALRKTG-KPGKCSRIVIMSSATHYGGRLT--LDDLQGR-LCYSSHAAYAQSKLALLLLSYHLQEQLLVRGDPVTVNAVDPGMVDTALYDNLCSPAQVAKKPFAKLLFRTPAEGASTAIYAAAASELEGIGGLYLYNGRKTESSALSYDKRLQTKLWKQSCALVGLK------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8J8YGQ6-1", "uniprot_id": "A0A8J8YGQ6_RAT", "id": "A0A8J8YGQ6-1", "name": "Polyprenol dehydrogenase", "aln": "---MLAALWAALRVYAVGVAVTMVQLLRRLRGGFRPPELPLQADRVAIVTGATRGVGLSTACQLARLGMRVIVAGNDEHRGHEVVARIQEESGPESAHFLFLDLASLSSVRSFVRNFEATALPLHLLINNAGVMLDPSGNTKDGFERHVGVNFLGHFLLTSLLLPALRASG-HQGRKSRVITVCSSTHWVGQAD--VARLLGQSPAPCALAAYAGSKLALALFSLRLQRLLSALGDPVTANIVDPGVVDTALFAHAGWGTRAVQRFLGWLLFKTPDEGAWTSVYAAASPKLEGIGGRYLRDEAEAEVLGAARDLELQGHLWAESCRLTGAAWVAVGE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9LDY7-1", "uniprot_id": "Q9LDY7_ARATH", "id": "Q9LDY7-1", "name": "", "aln": "-------MWPFWWKGASGFSARSTAEEVTHG--------IDGTGLTAIVTGASSGIGEETTRVLALRGVHVVMAVRNTDSGNQVRDKILKEIPQAKIDVMKLDLSSMASVRSFASEYQSLDLPLNLLINNAGIMACPFLLSSDNIELQFATNHLGHFLLTNLLLERMKKTASESNREGRIVIVSSEGHRFAYREGVQFDKINDEARYNTLQAYGQSKLGNILHATELARLFKEQGVNITANSLHPGSIMTNLLRYHSFINTIGN-AVGKYVLKSIPQGAATTCYAALHPQAKGVSGEYLMDNNISDPNSQGKDKDLAKKLWEFSLRLTGEEES----", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. . . .*****.: *:* . : *. .::*::* .: . * . :* :* . ..: ***:*::***.*. .::: ***::*:****:* * :.*.:* :.. *.*******.*** :: :. . .: .*:: :.* * . . : **. ***. * : .* . : * :*.* :.** : * * : .. :::: :** *: *** .: :*:.* ** : :: . . * * :** * *.* ", "identical_positions": 79, "similar_positions": 95, "identity": "23.44%" }, { "cls_id": "homologset.oma.827550", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P51656-1", "uniprot_id": "DHB1_MOUSE", "id": "P51656-1", "name": "17-beta-hydroxysteroid dehydrogenase type 1", "aln": "MDPTVVLITGCSSGIGMHLAVRLASDRSQSFKVYATLRDLKAQGPLLEAARTQGCPPGSLEILELDVRDSKSVAAAQACVTEGRVDVLVCNAGRGLFGPLEAHELNAVGAVLDVNVLGTIRMLQAFLPDMKRRHSGRVLVTASVGGLMGLPFHEVYCASKFALEGLCESLAILLPLFGVHVSLIECGAVHTAFYEKLVGG-PGGALERADAQTRHLFAHYLRGYEQALSEAQ-DPEEVTELFLTAMRAPQPALRYFSTNRFLPLARMRTEDPSGSSYVAAMHQEAFSNLQTQENAKAGAQVPGVSDTASSALICLPECAIPRVASELGWSASDKPGQDNSCYQQKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51657-1", "uniprot_id": "DHB1_RAT", "id": "P51657-1", "name": "Estradiol 17-beta-dehydrogenase 1", "aln": "MDSTVVLITGCSSGIGLHLAVRLASDRSQSFKVYATLRDLKSQGPLLEAARAQGCPPGSLEILELDVRDSESVAAARACVTEGRVDVLVCNAGRGLFGPLEAHELNAVGAVLDVNVLGTIRMLQAFLPDMKRRHSGRVLVTASVGGLMGLPFHEVYCASKFALEGLCESLAILLPLFGVHVSLIECGAVHTAFHEKLEGG-PGGALERADAQTRHLFAHYQRGYEQALSEAQ-DPEEVTELFLTAMRAPQPALRYFSTNRFLPLARMRTEDPSGSSYVEAMHREAFSDLQVQEGAKAGAQVSGDPDTPPRALICLPECAIPRVTAELGWSASDKPGQNKSCYQQKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14061-1", "uniprot_id": "DHB1_HUMAN", "id": "P14061-1", "name": "17-beta-hydroxysteroid dehydrogenase type 1", "aln": "MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGS-PEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVFLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFG--DVPAKAEAGAEAGGG--------------AGPGAEDEAGRGAVGDPELGDPPAAPQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QUP2-1", "uniprot_id": "F1QUP2_DANRE", "id": "F1QUP2-1", "name": "Estradiol 17-beta-dehydrogenase", "aln": "MEQKVVLITGCSSGIGLSLAVHLASNPAKAYKVYATMRNLDKKQRLLESVR--GLHKDTLDILQMDVTDQQSILDAQRNVSEGRIDILVCNAGVGLMGPLETHSLDTIRAILDVNLLGTIRTIQTFLPDMKKKRHGRILVTGSMGGLQGLPFNEVYCASKFAIEGACESLAILLQHFNIHISLIECGPVNTDFLMNLKRTEPGDKVLEVDAHTRSLYDQYLQHCQSVFQNAAQDTEDIIQVYLEAMEAQTPFLRYYTNRALLPMSSLKLTSMDGSQYIRAMSKLIFS--------------------------------SPGTDAQK-------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .************: ***:***: ::::*****:*:*. : * *:.* . .:*: *::** *.:*: *: *:***:*:****** **:****: ::: ::****::**:* :*:******:: **:***.*:*** ****::********:** *****:** *.:*:******.*:* * :: * : ..* :* : :* :..: :* :.*:: :::* *:.* * ***::.. :**: :: . .**.*: ** : *. * . : ", "identical_positions": 130, "similar_positions": 91, "identity": "37.57%" }, { "cls_id": "homologset.oma.827551", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQ06-1", "uniprot_id": "DHB11_MOUSE", "id": "Q9EQ06-1", "name": "Estradiol 17-beta-dehydrogenase 11", "aln": "MKYLLDLILLLPLLIVFSIESLVKLFIPKKKKSVAGEIVLITGAGHGIGRLTAYEFAKLNTKLVLWDINKNGIEETAAKCRKLGAQAHPFVVDCSQREEIYSAAKKVKEEVGDVSILVNNAGVVYTADLFATQDPQIEKTFEVNVLAHFWTTKAFLPVMMKNNHGHIVTVASAAGHTVVPFLLAYCSSKFAAVGFHRALTDELAALGRTGVRTSCLCPNFINTGFIKNPSTNLGPTLEPEEVVEHLMHGILTEKQMIFVPSSIALLTVLERIVPERFLQVLKHRINVKFDAVVGYKDK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYS8-1", "uniprot_id": "DHB11_RAT", "id": "Q6AYS8-1", "name": "Estradiol 17-beta-dehydrogenase 11", "aln": "MKYLLDLILLLPLLIVFCIESFIKRLIPKKKKSVAGEIVLITGAGHGIGRLTAYEFAKLNTKLVLWDINKNGIEETAAKCRKLGAQVHPFVVDCSQREEIYSAVRKVKEEVGDVSILVNNAGVVYTADLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMMKNNHGHVVTVASAAGHTVVPFLLAYCSSKFAAVGFHRALTDELAALGCTGVRTSCLCPNFINTGFIKNPSTNLGPTLEPEEVVEHLMHGILTNQKMIFVPGSIALLTVLERVFPERFLDVLKRRINVKFDAVVGYKDK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A3L7INX4-1", "uniprot_id": "A0A3L7INX4_CRIGR", "id": "A0A3L7INX4-1", "name": "Estradiol 17-beta-dehydrogenase 11", "aln": "MKYLLDFILMLPLLIVFCIESFVKLFIPKKKKSVAGELVLITGAGHGIGRLTAYEFAKLNTKLVLWDINKNGIEETAAKCRNLGAQAYPFVVDCSKRDEIYSAANKVKEEVGNVSILVNNAGVVYTSDLFATQDAQIEKTFEVNVLAHFWTTKAFLPEMMKNNHGHIVTVASAAGHTVVPFLLAYCSSKFAAVGFHRALTDELAALGRSGVKTSCLCPNFINTGFIKNPSTNLGPTLEPEEVVKHLMYGILTEKKMIFVPSALGFLMVLERIFPERFLAVLKHRINVKFDAVIGYKDK--", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q8NBQ5-1", "uniprot_id": "DHB11_HUMAN", "id": "Q8NBQ5-1", "name": "Estradiol 17-beta-dehydrogenase 11", "aln": "MKFLLDILLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKRKISVKFDAVIGYKMKAQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0XL59-1", "uniprot_id": "A0A8V0XL59_CHICK", "id": "A0A8V0XL59-1", "name": "Estradiol 17-beta-dehydrogenase 11", "aln": "MNPALGLLVFLGTLLYAYAEALVKLLLPAKRKAVRGELVLVTGAARGLGRATAREFARRQSRLVLWDVEAHGLKETATECEGLGATVHTFVVDCSKREEIYSAAEKVKKDIGDVSILVNNAGVITAADLLSTQDHQIEKMFEVNILAHIWTTRAFLPTMMKNNHGHIVTVASAAGQFVTSFMVAYCASKFAAVGFHKALTEELSSLGKDGIKTTCLCPVFMNTGFVKNPSTRLGKILEVDEVVKALMEGILTNQKMVFVPPQLSFALLSEMLIPERASNVLKKLTDVKFDAVVGHGSNQ-", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *.::::* *: *:::* ::* ::*:* **:**:***.:*:** ** ***: :::*****:: :*::***::*. *** .:.******:*::***:..*** ::*:**********: ::**::*** **** ****:***:***:**** * ******:********: ..*::***:*********::**:**::* *::*:**** *:****:***** ** ** :***: ** ****:::*:*:* :.: * :.*** ***: .******:*: : ", "identical_positions": 163, "similar_positions": 86, "identity": "54.33%" }, { "cls_id": "homologset.oma.827552", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P37059-1", "uniprot_id": "DHB2_HUMAN", "id": "P37059-1", "name": "17-beta-hydroxysteroid dehydrogenase type 2", "aln": "MSTFFSDTAWICLAVPTVLCGTVFCKYKKSSGQLWSWMVCLAGLCA-VCLLILSPFWGLILFSVSCF-LMYTYLSGQELLPVDQKAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNIAGTSDKWEKLEKDILDHLPAEVQEDYGQDYILAQRNFLLLINSLASKDFSPVLRDIQHAILAKSPFAYYTPGKGAYLWICLAHYLPIGIYDYFAKRHFGQDKPMPRALRMPNYKKKAT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A287BB42-1", "uniprot_id": "A0A287BB42_PIG", "id": "A0A287BB42-1", "name": "", "aln": "MGTFFSETGWLCLTVTAVLGAVILCKLKKNHRQEGRKMVCLAGLWGGACLLSLSLFWGLILFSLSCF-LMYAYFSGQEFLPVDQKAVLITGGDSGIGHALSKYLDKLGFTVFAGVLDEKGSGAEELRRTCSKHLSVLQLDITNSQQIRDAHSKVMEKVQNRGLWAVVNNAGILGFPIDGELIPMTQYKRCMAVNFFGAVEVTKAFLPLLRKSKGRLVNISSMAGGVPMEKMAAYSSTKAALTMFSAVMRKELSKWGVKVSVIQPGSFQTNIAGTSDLWDKLEKNILDDLTPNLQEDYGQDYILKQRSFLKFMSNSSEPDVSPVLLDVQHAISAKSPYAFYTPGKMSFLWLCFASFSPTVLFDYFSKSSHSFTRGMPRALSKANWKNEAM", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "P51658-1", "uniprot_id": "DHB2_MOUSE", "id": "P51658-1", "name": "Estradiol 17-beta-dehydrogenase 2", "aln": "MSPFASESAWLCLAAAAVLGGTLLCGCR-SGRQLRSQAVCLAGLWGGACLLSLSLLCTLFLLSVACFLLLYMSSSDQDLLPVDQKAVLVTGADSGFGHGLAKHLDKLGFTVFAGVLDKEGPGAEELRKHCSERLSVLQMDVTKPEQIKDAHSKVTEKIQDKGLWAVVNNAGVFHLPIDGELIPMSIYRKCMAVNFFGTVEVTKAFLPLLRKSKGRLVNVSSMGGTVPLQMTSAYAATKAALTMFSTIIRQELDKWGVKVVTIKPGGFKTNITGSQDIWDKMEKEILDHFSKDIQENYGQDYVHTQKLIIPTLKERSNPDITPVLRDIQHAISARNPSSFYYPGRMAYLWVCLAAYCPTSLLDYVIKKGFYP-QPTPRALRTVH------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62730-1", "uniprot_id": "DHB2_RAT", "id": "Q62730-1", "name": "Estradiol 17-beta-dehydrogenase 2", "aln": "MNPFSSESAWLCLTATAVLGGMLLCKAW-SSGQLRSQVVCLAGLWGGACLLSLSLLCSLFLLSVSCFFLLYVSSSDQDLLPVDQKAVLVTGADSGFGHALAKHLDKLGFTVFAGVLDKEGPGAEELRKNCSERLSVLQMDVTKPEQIKDVHSEVAEKIQDKGLWAVVNNAGVLHFPIDGELIPMTVYRKCMAVNFFGAVEVTKVFLPLLRKSKGRLVNVSSMGAMIPFQMVAAYASTKAAISMFSAVIRQELAKWGVKVVTIHPGGFQTNIVGSQDSWDKMEKEILDHFSKEIQENYGQEYVHTQKLALPVMREMSNPDITPVLRDIQHAICAKNPSSFYCSGRMTYLWICFAAYSPISLLDYILKNYFTP-KLMPRALRTAS------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*..* *::.*:**:..:** . ::* . * ****** . .*** ** : *:*:*::** *:* *.*::*********:**.*.*:**.*.*:**:**********:::*.******: ** :*****:*:*:. **:*.:*:* :*::*****:****:: :* ****: *: *::********:*****.**************:***.. *:: ::*.::***::***:::* ** ***:** *:**.* ***.*:.* *:*:**:***.:. ::**:***:*: *: : : . :. *.:*** *:**** *:.* ::* .*: ::**:*:* : * : **. * . : **** ", "identical_positions": 191, "similar_positions": 116, "identity": "49.1%" }, { "cls_id": "homologset.oma.827556", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O08699-1", "uniprot_id": "PGDH_RAT", "id": "O08699-1", "name": "15-hydroxyprostaglandin dehydrogenase [NAD(+)]", "aln": "-----------------MHVNGKVALVTGAAQGIGKAFTEALLLHG-AKVALVDWNLETGVKCKAALDEQFEPQKTLFIQCDVADQKQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEQTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINISSIAGLMPVAQQPVYCASKHGIIGFTRSAAMAANLMKSGVRLNVICPGFVKTPILESIEKEENMGQYIEYTDQIKAMMKFYGILDPSAIANGLINLIEDDALNGAIMKITASKGIHFQDYDLFPSFSKAP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCC1-1", "uniprot_id": "PGDH_MOUSE", "id": "Q8VCC1-1", "name": "15-hydroxyprostaglandin dehydrogenase [NAD(+)]", "aln": "-----------------MHVNGKVALVTGAAQGIGKAFAEALLLHG-AKVALVDWNLEAGVKCKAALDEQFEPQKTLFVQCDVADQKQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEQTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIIGFTRSAAMAANLMKSGVRLNVICPGFVDTPILESIEKEENMGQYIEYKDQIKAMMKFYGVLHPSTIANGLINLIEDDALNGAIMKITASKGIHFQDYDISPLLVKAPLTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15428-1", "uniprot_id": "PGDH_HUMAN", "id": "P15428-1", "name": "15-hydroxyprostaglandin dehydrogenase [NAD(+)]", "aln": "-----------------MHVNGKVALVTGAAQGIGRAFAEALLLKG-AKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNGAIMKITTSKGIHFQDYDTTPFQAKTQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VV42-1", "uniprot_id": "Q9VV42_DROME", "id": "Q9VV42-1", "name": "Fat body protein 2", "aln": "MKPQGIPPTTTRISQTKMSFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIID--LQDNLEEFVKLRAAHPTQSVMIIKMDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDKDVQRTLLVNLGGIINSTLSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRSGIKFVTVCPGATMTDMFTNFTEK---IIFPETSDETYRILDRLNKQSAADVSRCILNVLEKDK-NGAVYVIEGKRVYPLEIKPQWTGKEQAL---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ..** *:***.* *** .:: ** * ****::* *: .:: . * . .*..:::: ***::: :. *:.::.. **.:**:** **: *:*: ::** :** .:*..* .* **.*:***:***::*:**:.** *: *** *:* **:.***. * .**::: .:*** . * :: .: :: : * .*. ::. . .. ::. ::.::*.* ***: * .: :: . :: ", "identical_positions": 83, "similar_positions": 99, "identity": "28.92%" }, { "cls_id": "homologset.oma.827557", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B2GV72-1", "uniprot_id": "CRB3_RAT", "id": "B2GV72-1", "name": "Carbonyl reductase [NADPH] 3", "aln": "--------------------------------MSSCSRVALVTGANKGIGFAITRDLCRKFSGDVVLTARDEARGRAAVKQLQAEGLSPRFHQLDIDNPQSIRALRDFLRKEYGGLNVLVNNAGIAFRMDDPTPFDVQAEVTLKTNFFATRNVCTELLPIMKPHGR---VVNVSS----LQGLKALENCSEDLQERFRCDTLTEGDLVDLMKKFVEDTKNEVHEREGWPD--SAYGVSKLGVTVLTRILARQLDEKRKADRILLNACCPGWVKTDMARDQGSRTVEEGAETPVYLALLPPDATEPHGQLVRDKVVQTW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75828-1", "uniprot_id": "CBR3_HUMAN", "id": "O75828-1", "name": "Carbonyl reductase [NADPH] 3", "aln": "--------------------------------MSSCSRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNELLPIMKPHGR---VVNISS----LQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHEREGWPN--SPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSIRTVEEGAETPVYLALLPPDATEPQGQLVHDKVVQNW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9FI45-1", "uniprot_id": "Q9FI45_ARATH", "id": "Q9FI45-1", "name": "Short-chain dehydrogenase/reductase", "aln": "MVGSKEKSKEKRDKRLQEISLLRTIPYSDHQRWWTSETVAVVTGANRGIGFEMVRQLAG-HGLTVILTSRDENVGVEAAKILQEGGFNVDFHRLDILDSSSIQEFCEWIKEKYGFIDVLINNAGVNYNVGSDNSVEFS-HMVISTNYYGTKNIINAMIPLMRHACQGARIVNVTSRLGRLKGRHSKLENEDVRAKLMDVDSLTEEIVDKTVSEFLKQVEEGTWESGGWPHSFTDYSVSKMAVNAYTRVLAKELSERPEGEKIYANCFCPGWVKTAMTGYAGNVSAEDGADTGVWLALLPDQAIT--GKFFAERREISF", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. **:*****:***: :.*:*. .. *:**:** * *.: ** *:. **:*** : .**: : ::::::** ::**:***.: :. .. ..:.. .:.:.**::.*:*: . ::*:*: : :**::* *: :: : .: : : ::*** : . :.:*:::.:: . * ***. : *.***:.*.. :*:**:.*.*: :.::* *. *** *** * . :.*:**:* *:***** :* *::. :: .:", "identical_positions": 85, "similar_positions": 116, "identity": "26.73%" }, { "cls_id": "homologset.oma.827563", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZEZ3-1", "uniprot_id": "D3ZEZ3_RAT", "id": "D3ZEZ3-1", "name": "Dehydrogenase/reductase SDR family member 4", "aln": "MGLSSMATIFRSIPRAFRGYLCAPVPLSARKFSQLTDENRTLAGKVAVVTGSTRGIGFAIARRMARDGAHVVISSRKQENVKEAVDILKEEGLSVTGTVCHVGKAEDRQHLVTTALKHSGGIDFLVCVAGVNPLVGSTLAASEQIWDKILDVNVKSPALLLSQVLPHMENRGGGCVVLVSSAVAYLPVPRLGVYNTSKTALLGLCKSLAVELAPKGIRVNCLAPGIIKTDFSLREETMPNMLPELKKVFGVQRLGEPEECAGLVSFLCSSDGSYITGENIVVGGFSPKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A9J7F2T0-1", "uniprot_id": "A0A9J7F2T0_CRIGR", "id": "A0A9J7F2T0-1", "name": "Dehydrogenase/reductase SDR family member 4", "aln": "-----MAAMFRSVPQIFRGHQFASVPLSARMFSKRADEKRPLADKVAVITGSTKGIGFAIAQRLAQNGAHVVISSRKQQNVDRAVATLKEEGLSVTGTVCHVGKAKDRQHLVDTALEHSGGVDFLVCVAGVNPLVGSTLGASEQIWDKILDVNVKSPALLLSQLLPHMEKRGGSCVVLVSSVAAYIPVPKLGVYNTSKAALLGLCKSLAIELAPKGIRVNCLVPGIIKTDFGLGEKTVPNLLPELNKIYGLQRFGEPEDCAGIVSFLCSPDARYITGENIIVAGFSPKL", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **::***:*: ***: *.****** **: :**:*.**.****:****:*******:*:*::***********:**..** ******************:****** ***:****:*****************.***********************:*****:***.*******..**:***:********:**********:************.********.* *:*:**:****:*::*:**:****:***:******.*. *******:*.******", "identical_positions": 225, "similar_positions": 49, "identity": "77.85%" }, { "cls_id": "homologset.oma.827568", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q92781-1", "uniprot_id": "RDH5_HUMAN", "id": "Q92781-1", "name": "Retinol dehydrogenase 5", "aln": "MWLPLLLGALLWAVLWLLRDRQSLP-ASNAFVFITGCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQR-VASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGGGYCVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQAHYGGAFLTKYLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYLPASLVDAVLTWVLPKPAQAVY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27979-1", "uniprot_id": "RDH5_BOVIN", "id": "Q27979-1", "name": "Retinol dehydrogenase 5", "aln": "MWLPLLLGVLLWAALWLLRDRQCLP-ASDAFIFITGCDSGFGRLLALRLDQRGFRVLASCLTPSGAEDLQR-VASSRLHTTLLDVTDPQSIRQAVKWVETHVGEAGLFGLVNNAGVAGIIGPTPWQTREDFQRVLNVNTLGPIGVTLALLPLLLQARGRVINITSVLGRLAANGGGYCVSKFGLEAFSDSLRRDVAPFGVRVSIVEPGFFRTPVTNLETLEDTLQACWARLPPATQALYGEAFLTKYLRVQQRIMNMICDPDLAKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYLPARLVDAVLAWVLPKPAQTVY", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "O55240-1", "uniprot_id": "RDH5_MOUSE", "id": "O55240-1", "name": "Retinol dehydrogenase 5", "aln": "MWLPLLLGALLWAVLWLLRDRQSLP-ASDAFIFITGCDSGFGRLLALQLDQKGFQVLAGCLTPSGAEDLQQ-MASSRLHTTLLDITDPQNVQQVAKWVKTRVGETGLFGLVNNAGVAGIIGPTPWLTQDDFQRVLSVNTLGPIGVTLALLPLLQQARGRVVNITSVLGRIAANGGGYCVSKFGLEAFSDSLRRDMAPFGVQVSIVEPGFFRTPVTNLESLESTLKACWARLPPAIQAHYGEAFLDTYLRVQRRIMNLICDPELTKVTSCLEHALTARHPRTRYSPGWDAKLLWLPASYLPARVVDAVLTWILPRPAQSVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1L1RT00-1", "uniprot_id": "A0A1L1RT00_CHICK", "id": "A0A1L1RT00-1", "name": "", "aln": "MWLYLLLVVLAWALGWLVRDRQTLPSVKDKHVFITGCDSGFGNLLARRLAQRGFRVLAACLTPQGADGLQR-GCAGHLRTTLLDVTRSDSIRRAAEWVREEVGEKGLFGLVNNAGVANPIGPTEWMRIEDYRQVMAVNTFGAIEVTLQLLPLLKRARGRVVNTSSVLGRLSANGGGYCVSKYCIEAFSDSLRRDMYHFGVKVSIVEPGFFKTAVTNLESIEASLRQLWERLAPETRLSYGEEFFHKYLKVQRFIMNIICDADLGKVTRCMEHALGACHPRTRYSAGWDAKLLWLPASYLPACIVDFVLATILPKPAHHVR", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "D3ZKU7-1", "uniprot_id": "BL1S1_RAT", "id": "D3ZKU7-1", "name": "Biogenesis of lysosome-related organelles complex 1 subunit 1", "aln": "------------MLSRLLKEHQAKQNERKELQ---------------EKRRREAITAATCLTEALVDHLNVGVAQAYMNQRKLDHEVKTLQVQAAQFAKQTG----------------------------------------------------QWIGMVENFNQALKEIGD-----------VENWARSIELDMRTIATALEYVYKGQLQSAPS---------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::::* . . :: . * *** .: *: . . :. ** :..::.. : * * * ...* .:. :* :: *:. *: :. :. * * :::. : ", "identical_positions": 18, "similar_positions": 45, "identity": "5.62%" }, { "cls_id": "homologset.oma.827569", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VE80-1", "uniprot_id": "Q9VE80_DROME", "id": "Q9VE80-1", "name": "", "aln": "MGFIFGWLSTEHYVRDIFLMTSVAAIVATLMSIRFYLRITAGRCFTETKMEGKTVIITGANSGIGKETAKDLAGRG-ARIIMACRNLETANAVKDEIVKETKNNKILVKKLDLGSQKSVREFAADIVKTEPKIDVLIHNAGMALAFRGQTSEDGVELTMATNHYGPFLLTHLLIDVLKKSAP-ARIVIVASELYR-------LSSVNLAKLNPIGTFPAAYLYYVSKFANIYFARELAKRLEG--TKVTVNFLHPGMIDSGIWRNVPFPLNLPMMAITKGFFKTTKAGAQTTIYLATSNEVANVSGKYFMDCKEATLNAAALDEEKGLKIWEESVKIVKLTPQDPKI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q556S5-1", "uniprot_id": "Q556S5_DICDI", "id": "Q556S5-1", "name": "", "aln": "-----------------------------------------MESSSSSLLDKKVIIFSGGTDGIGRNSLNYLILEDNLKFILPVRNIEKGEKVVKELKEIKANVDIKLMKMDLSSFESIKEFVKEFNELNEPLDILVNNAGLINTEFKTTS-DGYESTMGVNHLGPSLLTLLLLPKLNQSKHGGNIVFVASKMHDRVTQLDFEQTLGKEDKNNTDFSSSNYEYSKSKLYNILFSKELQNKLIEKGSDIKVNSLHPGFAVTHLFEKHGWFANNLVLPVLV-YFKGNKLDDMGSALANLTLNKLNEKGKYFTLTKITEPSKFASNPNNTINLWNKTCKLLSIDFNKINL", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :.: :: *.:*::*...***::: : * .. ::*:. **:*..: * .*: : . * .* : *:**.* :*::**. :: : : :*:*::***: : ** ** * **..** ** *** **: *::* ..**:***::: .::. . * . .: * * **: ** *::** ::* :.:.** ****: : ::.: : * ::.: :** .* . : : : * .**** * : . * : :: :::*::: *::.: :. ::", "identical_positions": 80, "similar_positions": 115, "identity": "23.05%" }, { "cls_id": "homologset.oma.827572", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NYR8-1", "uniprot_id": "RDH8_HUMAN", "id": "Q9NYR8-1", "name": "Retinol dehydrogenase 8", "aln": "MAAAPRTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQLDVCSDESVAQCLSCIQG-EVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFISLVEPGPVVTEFEGKLLAQVSMAEFPGTDPETLHYFRDLYLPASRKLFCSVGQNPQDVVQAIVNVISSTRPPLRRQTNIRYSPLTTLKTVDSSGSLYVRTTHRLLFRCPRLLNLGLQCLSCGCLPTRVRPR-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9N126-1", "uniprot_id": "RDH8_BOVIN", "id": "Q9N126-1", "name": "Retinol dehydrogenase 8", "aln": "MADAPRTVLISGCSSGIGLELAVQLAHDPRQRYQVVATMRDLGKKGTLETAAGEALGQTLTVAQLDVCSDESVAQCLNCIQGGEVDVLVNNAGVGLVGPLEGLSLAAMQNVFDTNFFGAVRLVKAVLPSMKRRRQGHIVVVSSVMGLQGVVFNEVYAASKFAMEGFFESLAVQLLQFNIFISLVEPGPVVTEFEGKLLEQVSTAEFPGTDPDTLSYFRDLYLPASRELFHNVGQSPQDVAKVIVKVIGSARPPLRRRTNTRYTPLIALKAMDPSGSLYVRTSHCLLFRWPRLLNLGLRCLACSCFRTPVWPR-----", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "D4A8D2-1", "uniprot_id": "D4A8D2_RAT", "id": "D4A8D2-1", "name": "Retinol dehydrogenase", "aln": "MASQPQRVLISGCSSGIGLELAVQLAHDPRQRYQVVATMRDLGKKEPLEAAAGEALGKTLSVAQLDVCSDESVTNCLSHIEGGQVDILVNNAGVGLVGPLEDLSLATMQNVFNTNFFGAVRLVKAVLPGMKRRRQGHIVVVSSVMGLQGVMFNDVYAASKFALEGFFESLAIQLRQFNIFISMVEPGPVITDFEGKLLAQVSKTEFPDTDPETLGYFRDLYLPASRELFRSVGQSPRDVAQVIAKVIGSTRPPLRRQTNARYFPLTALKALDPSGSLYVRTTHRLLFRWPHLLSLGLRCLACGCLPTRVGPT-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z6W3-1", "uniprot_id": "D3Z6W3_MOUSE", "id": "D3Z6W3-1", "name": "Retinol dehydrogenase", "aln": "MASQQRTVLISGCSSGIGLELALQLAHDPRQRYQVVATMRDLGKKEPLEAAAGEALGKTLSVVQLDVCNDESVTDCLSHIEGGQVDVLVNNAGVGLVGPLEGLSLATMQSVFNTNFFGAVRLVKAVLPGMKRRRQGHIVVVSSVMGLQGVMFNDVYAASKFALEGFFESLAIQLRQFNIFISMVEPGPVTTDFEGKLLAQVSKAEFPDTDPDTLGYFRDLYLPASRELFRSVGQSPRDVAQVIAKVIGTTRPPLRRQTNTRYLPLTALKAMDPSGSLYVKTAHRLLFRWPHLLNLGLRCLACGCLPTRVWPRQTEQN", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : ***************:******::************** .**:*******:**:*.*****.****::**. *:* :**:******:*******.****:**.**:***************.***********:*********:**:********:********:** *******:****** *:****** *** :***.***:** ***********:** .***.*:**.:.*.:**.::******:** ** ** :**::*.******:*:* **** *:**.***:**:*.*: * * * ", "identical_positions": 233, "similar_positions": 57, "identity": "73.5%" }, { "cls_id": "homologset.oma.827580", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P38342-1", "uniprot_id": "KDSR_YEAST", "id": "P38342-1", "name": "3-ketodihydrosphingosine reductase TSC10", "aln": "----------------------MKFTLEDQVVLITGGSQGLGKEFAKKYYNEAENTKIIIVSRSEARLLDTCNEIRIEAHLRRETTDEGQVQHKLAAPLDLEQRLFYYPCDLSCYESVECLFNALRDLDLLP--TQTLCCAGGAVPKLFRGLSGHELNLGMDINYKTTLNVAHQIA---LAEQTKEHHLIIFSSATALYPFVGYSQYAPAKAAIKSLVAILRQELTNFRIS--CVYPGNFESEGFTVEQLTKPEITKLIEGPSDAIPCKQACDIIAKSLARGDDDVFTDFVGWMIMGMDLGLTAKKSRFVPLQWIFGVLSNILVVPFYMVGCSWYIRKWFRENDGKKAN", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q556J2-1", "uniprot_id": "KDSR_DICDI", "id": "Q556J2-1", "name": "3-ketodihydrosphingosine reductase", "aln": "MIIYILFSLLAAVIVHLVYKKQTGFKLKGKHIVVVGGSSGIGKELVYELLKENIAS-ISVISRSLDKLRSVVDDCPSEVCTKSTPLNVG----------SLKSKIEIYSCDITNKIKVKETIAQIVSKNQGGKIDCLINCAGFAIPGYFIEQDEEIFEKTMQLDYFGSLYATKEVVPLMIENGGQGGHIVFVSSTCGLVGVPGYSTYCPSKFALRGLAETLRSELKPYKITFSVVYPPDTDTPGYQQENLTKPEETVAISGGGKAVSPLEVAKSIVSGIKNGDYHIAYDVPTKLCAVLSPGLTP--FYFSFFDILLAPICRLVGIIAMNQNDAEVLKSWKKRNQLKK--", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.*:.: :::.***.*:***:. : :* : * ::*** :* .. :: *. : . : * .*:.:: *.**:: .*: : : . : : *** *:* * . . :: *:::* :* .::::. : : : *:::.**: .* . *** *.*:* *::.*. **.**. ::*: *** : :: *: *:***** * *.* ..*:. :... *...: .** .: *. : :. ***. * :: ::. :..:: : . : ::.* :.*: ** ", "identical_positions": 74, "similar_positions": 122, "identity": "21.2%" }, { "cls_id": "homologset.oma.827583", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VCR2-1", "uniprot_id": "DHB13_MOUSE", "id": "Q8VCR2-1", "name": "17-beta-hydroxysteroid dehydrogenase 13", "aln": "MNLILEFLLLVGVIIYSYLESLVKFFIPRRRKSVTGQTVLITGAGHGIGRLTAYEFAKQKSRLVLWDINKRGVEETADKCRKLGAVVHVFVVDCSNRAEIYNSVDQVKREVGDVEIVVNNAGAIYPADLLSAKDEEITKTFEVNILGHFWIIKALLPSMLRRNSGHIVTVASVCGHGVIPYLIPYCSSKFAAVGFHRALTAELDTLGKTGIQTSCLCPVFVNTGFTKNPSTRLWPVLEPEEVARSLINGILTNKKMIFVPSYINISLILEKG-PGFSSKHPHGGSQQPVTPIPGDLTPSSDFLKH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M875-1", "uniprot_id": "DHB13_RAT", "id": "Q5M875-1", "name": "17-beta-hydroxysteroid dehydrogenase 13", "aln": "MNLILELLLLVGIIIYSYLESLVKFFIPQRRKSVAGQTVLITGAGHGIGRLTAYEFAKQKSRLVLWDISKHGVEETAAKCRKLGAVVHVFVVDCSNRAEIYKSVDQVKKEVGDIEIVVNNAGAIYPADLLSTKDEEITKTFEVNILGHFWIIKALLPSMLRRNSGHIVTVASVCGHRVIPYLIPYCSSKFAAVGFHRALTAELDTLGKTGIKTSCLCPVFVNTGFTKNPSTRLWPVLEPDEVARSLIDGILTNKKMIFVPSYINISLIVEMFFPERVLKAINRIQNIQFEAIVGHRTKRK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z5P4-1", "uniprot_id": "DHB13_HUMAN", "id": "Q7Z5P4-1", "name": "17-beta-hydroxysteroid dehydrogenase 13", "aln": "MNIILEILLLLITIIYSYLESLVKFFIPQRRKSVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVTAHAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPVFVNTGFTKNPSTRLWPVLETDEVVRSLIDGILTNKKMIFVPSYINIFLRLQKFLPERASAILNRMQNIQFEAVVGHKIKMK-----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:***:***: ***************:*****:*: ************ *:*****::* ******.*:****** :*****...*.:******* ***.*::***:****: *******::*******:******************* *******:.** ************ *******************.**:**::******:**************************.:**.****:***************** * :: * : .: . .: *. . ", "identical_positions": 220, "similar_positions": 46, "identity": "72.13%" }, { "cls_id": "homologset.oma.827591", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9SY73-1", "uniprot_id": "PTALR_ARATH", "id": "Q9SY73-1", "name": "NADPH-dependent pterin aldehyde reductase", "aln": "MTMATPFSGAANSIVAARTVLITGVSKGLGRALALELAKRGHTVIGCARSQEKLT-ALQSELSSSTNHLLLTADVKSNSSVEEMAHTIVEKKGVPDIIVNNAGTINKNSKIWEVSAEDFDNVMDTNVKGVANVLRHFIPLMLP----RKQGIIVNMSSGWGRSG-AALVAPYCASKWAIEGLSRAVAKEVVEG-MAVVALNPGVINTELLT----SCFGNSASLYQAP---------------DAWAVKAATMILNLTAGDNGGSLTV----------------------------------", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q54FW2-1", "uniprot_id": "Q54FW2_DICDI", "id": "Q54FW2-1", "name": "", "aln": "-----------MSQNDKKVFYITGASKGFGLELTNQLLERGFNVVATSRNKQQLSNSVNNKFVTNDNFLALQVDLTSNESVKNSIDETISKFTRIDVIINNAG-YSQCGTIEELTDKEIRDNFECNVFGVISVIRNALPHLRINKFFANGPRIINISSIAGFTGSFPGFSIYSSTKFALEGLTEGLNEDLKEFGIHASTVLPGYFRTSFLEKGSVAVPSHPIKEYTAVRKIQEIHENQINGNQQGDPVKGCKVIIDHALSENPTTHLFLGPDSMKYAQSKIEAIQNDIKSNYDAASKTDFTN", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :.. ***.***:* *: :* :**..*:. :*.:::*: :::.:: :. *.* * .*:.**.**:: . :.* *:*:**** .: ..* *:: ::: : :: ** ** .*:*: :* : : *:*:** * :* . .: *.::*:*:***:..: ::: * : . :: ** :.*.:* : .:. . * * :. .**...:*:: : .:* : . ", "identical_positions": 62, "similar_positions": 101, "identity": "20.53%" }, { "cls_id": "homologset.oma.827595", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1MG20-1", "uniprot_id": "F1MG20_BOVIN", "id": "F1MG20-1", "name": "", "aln": "MWLYLAVLLGLYYLLRWYQERQVVSHLQDKFVFITGCDSGFGNQLARQLDLRGLRVLAGCLTEQGAEQLRNQTSDRLQTVILDVTKTESIAAATEWVKECVGDRGLWGLVNNAGIFHSHGYAEWIKIETYRDTLRVNLIGVIEVTLSMLPLVRKAQGRIVNVSSILGRIAFFGAVYSCSKYGVEAFSDILRRELQHFGVKVSMVEPGYFRTAMTDWQKFSEIMKQIWKETPAHIKETYGQKFFDAYHDLMKQGLLSCSTNLNLVTDCMEHALTSVHPRTRYSAGWDAQFFFVPLSYLPTSLADYILTRSWPKPAQAV", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A4X1W6H0-1", "uniprot_id": "A0A4X1W6H0_PIG", "id": "A0A4X1W6H0-1", "name": "", "aln": "MWLYLAVLVGLYYLLRWYRERQMVSHLGDKYVFITGCDSGFGNLLARQLDVRGLRVLAACLTEQGAQQLRKQTSDRLETVLLDVTKTESIAAATQWVKERVGDRGLWGLVNNAGTFHPLCITEWLKTETWIHTLKVNLIGVTEVTLSMLPLVKKAQGRIVNVSSILGRVAFFGAVYSSSKHGVEAFSDVLRCELQHFGVKVSIVEPGYFRTGMTDVQKSSEAMKQVWKEVPAHIKDTYGQKFFDAYHDVMKQGLSSCSTNLNLVTDCMEHALTSVHPRTRYSAGWDAQFFFIPLSYLPTSLADYILTRSWPKPVQAV", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "O14756-1", "uniprot_id": "H17B6_HUMAN", "id": "O14756-1", "name": "17-beta-hydroxysteroid dehydrogenase type 6", "aln": "MWLYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAACLTEKGAEQLRGQTSDRLETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGRVAFFVGGYCVSKYGVEAFSDILRREIQHFGVKISIVEPGYFRTGMTNMTQSLERMKQSWKEAPKHIKETYGQQYFDALYNIMKEGLLNCSTNLNLVTDCMEHALTSVHPRTRYSAGWDAKFFFIPLSYLPTSLADYILTRSWPKPAQAV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R092-1", "uniprot_id": "H17B6_MOUSE", "id": "Q9R092-1", "name": "17-beta-hydroxysteroid dehydrogenase type 6", "aln": "MWFYLVTLVGLYHLLRWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDRRGMRVLAACLTEKGAEELRNKTSDRLETVILDVTKTESIVAATQWVKERVGDRGLWGLVNNAGVLQPFAYIEWYRPEDYMPIFQVNLIGLTQVTISMLFLVKKARGRIVNVSSALGRVALFGGFYSCSKYGVEAFSDVLRHEVQDFGVKVSIIEPGSFKTEMTDAELTIERTKKVWEAAPEHIKESYGQQFFDDFCSTTKRELMKCSRNLSLVTDCMEHALTSTHPRTRYSAGWDAKFFFIPLSYLPASLVDYLLAISRGKPAQAA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O54753-1", "uniprot_id": "H17B6_RAT", "id": "O54753-1", "name": "17-beta-hydroxysteroid dehydrogenase type 6", "aln": "MWFYLVTLVGLYYLLRWYRERQVVSHLHDKYVFITGCDSGFGNLLARQLDRRGMRVLAACLTEKGAEELKSKTSDRLETVILDVTNTDSISAATQWVKEHVGDKGLWGLVNNAGVFQAFAYIEWCRPEDCMSIFQVNLIGLAQVTLSMLFLVKKARGRIVNVSSVLGRVALFGGFYSCSKYGVEAFSDVLRREIRDFGVKVSIIEPGSFKTRMTDAELIIEKTKKTWEATPEHIRESYGQQFFDDFCNTTRRELKKCSTNLSLVTDCMEHALTSKYPRTRYSAGWDARLFFIPLSYLPTSLVDCLLAISRRKPAQAV", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:**..::***:**:**:***:**** **:************ ****** **:****.****:**::*: :*****:** ****: :** ***:**** ***:********** : . ** . * ::*****: :**:*** **::*:******** ***:*:* . *. **:*******:** *::.****:*::*** *:* **: * *: *: .* **:::***::** . :. * .** **.************ :***********::**:******:**.* :*: * **.**.", "identical_positions": 194, "similar_positions": 70, "identity": "61.2%" }, { "cls_id": "homologset.oma.827597", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K354-1", "uniprot_id": "CBR3_MOUSE", "id": "Q8K354-1", "name": "Carbonyl reductase [NADPH] 3", "aln": "MSSCSRVALVTGANKGIGFAITRDLCRKFSGDVVLTARDEARGRAAVQQLQAEGLSPRFHQLDIDDPQSIRALRDFLRKEYGGLNVLVNNAGIAFRMDDPTPFDIQAEVTLKTNFFATRNVCTELLPIMKPHGRVVNISSLQGLKALENCREDLQEKFRCDTLTEVDLVDLMKKFVEDTKNEVHEREGWPDSAYGVSKLGVTVLTRILARQLDEKRKADRILLNACCPGWVKTDMARDQGSRTVEEGAETPVYLALLPPDATEPHGQLVRDKVVQTW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1SGX4-1", "uniprot_id": "F1SGX4_PIG", "id": "F1SGX4-1", "name": "Carbonyl reductase (NADPH)", "aln": "MSSYTRVALVTGANKGIGFAIARDLCRQFSGDVVLTSRDAARGRAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAGIAFKIDDPTPFDIQAEMTLKTNFFGTRNVCIELLPIIKPHGRVVNISSLLGSKALENCSEDLQEKFRCEALTEEDLVDLMKKFVEDAKNEVHEREGWPSSAYGVSKLGVTVLSRILAQRLDEKRKADRILLNACCPGWVKTDMTGGQGFETVEEGAVTPVYLALLPPDATEPQGQLVRDKVIQNW", "tax_id": 9823, "tax_name": "Pig" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** :****************:*****:********:** ************************** ****************************::***********:*******.***** *****:************ * ****** *********::*** ************:***********.*************:****::************************: .** .****** ***************:********:*.*", "identical_positions": 244, "similar_positions": 22, "identity": "88.09%" }, { "cls_id": "homologset.oma.827604", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1B0GRG8-1", "uniprot_id": "A0A1B0GRG8_MOUSE", "id": "A0A1B0GRG8-1", "name": "Carbonyl reductase (NADPH)", "aln": "MSPCS-RVALVTGGNKGIGFEIIRDLCQKFSGDVVLTARDEARGCAAVQKLQAEG----LNPRFHQLDIDDPQSIHALRDFLLKEYKGLDVLVNNAGIAFKVDDPTPFHIKG------------------EVTMKTNFFGTRDVCKEMLPLIKPQG--RVVNVSSMVS--LSALKDCSPELQQKFRSETITEEELVGLMNKYVEDAKKGVYVKEDWPN--SAYEVSKIGVTVLSRILARKLNEQRRGDKILLNACCPGWVRTDMTGPQATKSPEEGAETPVYLALLPPDAEGPHGQFVQDKTVEPW------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q28960-1", "uniprot_id": "CBR1_PIG", "id": "Q28960-1", "name": "Carbonyl reductase [NADPH] 1", "aln": "MSSNT-RVALVTGANKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQLQAEG----LSPRFHQLDIIDLQSIRALCDFLRKEYGGLDVLVNNAAIAFQLDNPTPFHIQA------------------ELTMKTNFMGTRNVCTELLPLIKPQG--RVVNVSSTEG--VRALNECSPELQQKFKSETITEEELVGLMNKFVEDTKNGVHRKEGWSD--STYGVTKIGVSVLSRIYARKLREQRAGDKILLNACCPGWVRTDMGGPKAPKSPEVGAETPVYLALLPSDAEGPHGQFVTDKKVVEWGVPPESYPWVNA", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q9M2E2-1", "uniprot_id": "SDR1_ARATH", "id": "Q9M2E2-1", "name": "(+)-neomenthol dehydrogenase", "aln": "MAEETPRYAVVTGANRGIGFEICRQLASEGIR-VVLTSRDENRGLEAVETLKKELEISDQSLLFHQLDVADPASITSLAEFVKTQFGKLDILVNNAGIGGIITDAEALRAGAGKEGFKWDEIITETYELTEECIKINYYGPKRMCEAFIPLLKLSDSPRIVNVSSSMGQLKNVLNEWAKGILS--DAENLTEERIDQVINQLLNDFKEGTVKEKNWAKFMSAYVVSKASLNGYTRVLAKKHPEFR------VNAVCPGFVKTDMNFKTGVLSVEEGASSPVRLALLP-HQETPSGCFFSRKQVSEF------------", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : * *:***.*:**** * *:*. : ****:** ** **: *: * . *****: * ** :* :*: .:: **:*****.*. : :. .:: . * :* *: *.: :* ::**:* .. *:***** . .*:: : : . :*.:***.: ::*: ::* *:*. ::.*.. *:* *:* .:. :*: *:* * * :** ***:*:*** . * * **.:** ***** . * * * *. * * : ", "identical_positions": 103, "similar_positions": 81, "identity": "32.39%" }, { "cls_id": "homologset.oma.827612", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1NLF1-1", "uniprot_id": "F1NLF1_CHICK", "id": "F1NLF1-1", "name": "", "aln": "MAAVDRFNLLYREISRSCSVYIEALAIVGAWYTVRKCLTLVFNTYSMIRLHALPKLVGEIDIVKRYGRWAVVTGSTDGIGKAYAEELAKRGVNIILISRSKEKLEAVSRSISETY-KVETDFIVADFSKGREAYQAIKEGLKDREIGILVNNVGLFYTYPDYFTNLSEDMLWDMINVNIASANMMVHIVLPGMVEKRKGAIVNVSS--ASCCQPTPMLTIYGASKAYLDYFSRALYYEYASKGIFVQSLTPFVIATKMVSCSRVTSKRSFFFPSAEEYASHAISTLGLSKRTPGYWKHSIEFTLGERLPEWIWAWFAQYFCRIIRKEALTHKAK", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9FYL6-1", "uniprot_id": "KCR2_ARATH", "id": "Q9FYL6-1", "name": "Very-long-chain 3-oxoacyl-CoA reductase-like protein At1g24470", "aln": "--------MQGACISESQPWYLHFVCFIGFLFLLRVLFIPLLKWFTTRFLLTP-------KRLKRYGSWAMVTGATEGIGRAFAHELAKHGLNLILVSRNLSKLESVSDDFQQEFPHIKIKIIPFDFS-SEGGYGAIEEGIKGLEVGILINNVGITYPRAMFFHEVDQLTWTKILRVNLEATTWVTRSLIGPMLHRRRGAIVNISSGAAVVVPSHPLYAIYAATKAYVDALSRSLHVEYKQFGIDVQCQVPLYVSTRMVSEVAAIDKPSLFVPSPEVYAKAAVAQIGIGSRCSPFWAHSLQWFLVGLVPDNLVDTWRLSIG--LRRRSLS----", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **.* . *:. :.::* : :* : ::: :: * : . :**** **:***:*:***:*:*.****:*:*:**:**. .***:** .:.: : ::: .:* *** .. .* **:**:*. *:***:****: *. . :* ::.: .::.**: ::. :.: :: *:.:*:*****:** * . *: :**.*:***:* :**:*: ** . ** **. .*: ::*:*** . .* *:*.**.* **. *:: :*:..* . :* **::: * :*: : : : :*:.:*: ", "identical_positions": 109, "similar_positions": 120, "identity": "32.63%" }, { "cls_id": "homologset.oma.827614", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VNF4-1", "uniprot_id": "Q9VNF4_DROME", "id": "Q9VNF4-1", "name": "Ketoreductase domain-containing protein", "aln": "----------------MGSKGKAG--------------------LDFSGKVVLITGAASGIGAAAAEMFSKLGACLALVDREEEGLICVMKRCMKMGHEP----YGIAGDLLKPPEIECIARKTTERYEGKLDVLVNGAGIMP-TGTLQSTELACFTHVMEANVRSGFYLTKLLLPQLLQCK---GSIVNVSSVCGLR--AFPNLVAYNMSKAAVDQFTRSLALDLGPQGVRVNAVNPGVIRTNLQKAGGMDEQSYAEFLEHSKKTHALGRIGEPKEVAAAICFLASELASFVTGVTLPVDGGKQVMCPR-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "F4IPI3-1", "uniprot_id": "F4IPI3_ARATH", "id": "F4IPI3-1", "name": "", "aln": "MSFWFRDKSLYVMGISFSTKEHTKRNNMSNHQTVREILLLLYLTCELKDKVVLVTGASSGIGREVCLDLAKAGCKIIAAARRVDRLKSLCSEINRFEYSAGIQAEALELDVSSDAATVQKAVKKAWEIFGKIDALINNAGFRGNVKSSLDLSEDEWDKVFKTNLTGTWLVSKYVCILMRDAKRGGGSVINISSVSWLHRGQVPGGVAYACSKGGVDTMTRMMALELGVYKIRVNSIAPGLLKSEITQG--LMQKEWLKTVIERTVPLKVQQTVDPG-LTSLLRYLVHDSSKYISGNTYIVDAGASLVGLPIFSSL", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:* :: ::..****:***:**** .. ::* *. : . *. : * .: .. :: :.. .: *: . . * *.: . **:*.*:*.**: . : . . : :*:::*: . : ::* : : :.* **::*:***. *: .*. *** **..** :** :**:** :***:: **:::::: :. : ::.: : : . . . : : :* ::: : :*. : :.:::* * **.* .:: ", "identical_positions": 63, "similar_positions": 112, "identity": "20.0%" }, { "cls_id": "homologset.oma.827622", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N5I4-1", "uniprot_id": "DHRSX_HUMAN", "id": "Q8N5I4-1", "name": "Polyprenol dehydrogenase", "aln": "MSPLSAARAALRVYAVGAAVILAQLLRRCRGGFLEPVFPPRPDRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLN----------------------DKVEFLYCDLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLLLDTLK----ESGSPGHSARVVTVSSATHYVAELNMDDLQ-SSACYSPHAAYAQSKLALVLFTYHLQRLLAAEGSHVTANVVDPGVVN-TDVYKHVFWA------TRLAKKLLGWLLFKTPDEGAWTSIYAAVTP--ELEGVGGHYLYNE-KETKSLHVTYNQKLQQQLWSKSCEMTGVLDVTL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A287AU92-1", "uniprot_id": "A0A287AU92_PIG", "id": "A0A287AU92-1", "name": "Polyprenol dehydrogenase", "aln": "MSPLSAARAALRVYAAGAAVILAQLLRRCRGGFAEPVFPPQPGRVAIVTGGTEGIGFATAKHLARLGMHVIIAGNNDSKAREAVRKIREETLN----------------------DKVEFLYCDLASMKSLRQFVQKFKMKKIPLHVLVNNAGVMMVPQRETEDGFEEHFGVNYLGHFLLTHLLLDDLQ----ASGSPGRSSRVVTVSSATHYVGELDLDDLQ-SSGGYSPHGAYARSKLALVLFSHRLQALLEAKGSPVTANVADPGVVN-TDLYRHVFWG------TRLLKKLFGWWFFKTPDEGAWTSVYAAVSP--ALEGVGGRYLYNE-KEAKSLAITYDPKLQRQLWARSCQMTGIADMSRDTLWG", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "O80924-1", "uniprot_id": "O80924_ARATH", "id": "O80924-1", "name": "", "aln": "MGIYGVMTGKKGKSGFGSASTAEDVTQAIDASHLT----------AIITGGTSGIGLEAARVLAMRGAHVIIAARNPKAANESKEMILQMNPN----------------------ARVDYLQIDVSSIKSVRSFVDQFLALNVPLNILINNAGVMFCPFKLTEDGIESQFATNHIGHFLLTNLLLDKMKSTARESGVQGRIVNLSSIAHTYTYSEGIKFQGIN-DPAGYSERRAYGQSKLSNLLHSNALSRRLQEEGVNITINSVHPGLVT-TNLFRYSGFS------MKVFRAMT-FLFWKNIPQGAATTCYVALHP--DLEGVTGKYFGDC-NIVAPSKFATNNSLADKLWDFSVFLIDSISK-------", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q08651-1", "uniprot_id": "ENV9_YEAST", "id": "Q08651-1", "name": "Probable oxidoreductase ENV9", "aln": "-------------------MLDPRILPYYDPAVER--------KIAVVTGGNTGIGWYTVLHLYLHGFVVYICGRNSHKISKAIQEILAEAKKRCHEDDDGSSPGAGPGPSIQRLGSLHYIHLDLTDLKCVERAALKILKLEDHIDVLVNNAGIMAVPLEMTKDGFEVQLQTNYISHFIFTMRLLPLLR------HCRGRIISLSSIGHHLEFMYWKLSKTWDYKPNMLFTWFRYAMSKTALIQCTKMLAIKYP----DVLCLSVHPGLVMNTNLFSYWTRLPIVGIFFWLLFQVVGFFFGVSNEQGSLASLKCALDPNLSVEKDNGKYFTTGGKESKSSYVSNNVDEAASTWIWTVHQLRDRGFDI-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *::***. *** :. * * * *...* : * : :.:: *::.:..:. . :: : :.:*:****:* * . *.**:* :: *::.**::* ** :: *: : ::. : . : .. *. ** : : : * : ..**:* *::: : : : : : . :*: :: *: * :* *:*: : . .: : . . * : . ", "identical_positions": 47, "similar_positions": 89, "identity": "12.63%" }, { "cls_id": "homologset.oma.827623", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P16232-1", "uniprot_id": "DHI1_RAT", "id": "P16232-1", "name": "11-beta-hydroxysteroid dehydrogenase 1", "aln": "-------------------------------------------------MKKYLLPVLVLCLG-YYYST----------NEEFRPEMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKV----------------------VSRCLELGAASAHYIAGTMEDMAFAERFVVEAGKLLGGLDMLILNH-ITQTTMSLFHDDIHSVRRSMEVNFLSYVVLSTAALPMLKQSNGSIAIISSMAGKMTQPLIASYSASKFALDGFFSTIRKEHLMTKVNVSITLCVLGFIDTETALKETSGIILSQAAPKE---ECALEIIKGTVLRKDEVYYD--KSSWTPLLLGNPGRRIMEF---LSLRSYNRDLFVSN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50172-1", "uniprot_id": "DHI1_MOUSE", "id": "P50172-1", "name": "11-beta-hydroxysteroid dehydrogenase 1", "aln": "----------------------------------------------MAVMKNYLLPILVLFLAYYYYST----------NEEFRPEMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKV----------------------VSRCLELGAASAHYIAGTMEDMTFAEQFIVKAGKLMGGLDMLILNH-ITQTSLSLFHDDIHSVRRVMEVNFLSYVVMSTAALPMLKQSNGSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTIRTELYITKVNVSITLCVLGLIDTETAMKEISGIINAQASPKE---ECALEIIKGTALRKSEVYYD--KSPLTPILLGNPGRKIMEF---FSLRYYNKDMFVSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28845-1", "uniprot_id": "DHI1_HUMAN", "id": "P28845-1", "name": "11-beta-hydroxysteroid dehydrogenase 1", "aln": "----------------------------------------------MAFMKKYLLPILGLFMAYYYYSA----------NEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKV----------------------VSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNH-ITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKE---ECALEIIKGGALRQEEVYYD--SSLWTTLLIRNPCRKILEF---LYSTSYNMDRFINK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8K3KFT3-1", "uniprot_id": "A0A8K3KFT3_BOVIN", "id": "A0A8K3KFT3-1", "name": "11-beta-hydroxysteroid dehydrogenase 1", "aln": "MSGKVHQALNFMLSQNSKDTLTGFLVSKLYCPSDLLLGLLVPDPCLMAFMKKYLLPILGIFLAYYYYSA----------NEEFRPEMLRGKRVIVTGASKGIGREMAYHLARMGAHVVVTARSEESLKKV----------------------VSRCLELGAASAHYVAGTMENMTFAEQFVAKAGELVGGLDMLILNH-IHYTPLGVFSNDIHLLRRTLEVNLLSYVVLSTAALPMLKQTNGSIVVVSSIAGKIACPLVAAYSASKFALDGFFSSLRMEYEATKVNVSITLCILGLIDTDTAMKAVAGIFNAKASPKE---ECALEIIKGGTLRQDEVYYD--SSILTPLLLRNPGRKIMEF---FFLKKYNMERFINN", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A8V1A2W5-1", "uniprot_id": "A0A8V1A2W5_CHICK", "id": "A0A8V1A2W5-1", "name": "11-beta-hydroxysteroid dehydrogenase 1", "aln": "----------------------------------------------MGLLQKILIPVLGLVLAFCFYSS----------RENFRPEMLKGKRVIVTGASTGIGEQMAYHLARMGAHVLVTARTEAKLQQVNGKLGTHTCTHKHRKANLTSQVVERCRALGAGSARLVSGSMEDMATTRQLVEVAEAELGGLDMLILNH-VGKSYFNYFDGDVGHVQKLLNINFLSYVAMTVSALPMLKRSGGSIVVVSSMAGKVGFPFTVPYSATKFALDGFFSSLRQEFNIQSVNVSITLCILGFIDTENAMRAAADVLLMSPAPKE---ECALEIIKGGTLRQREVYYRY-ASTKLPLLLRDWAAELLDL---LVRQRYRPERLRAA", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9STY7-1", "uniprot_id": "HSD3_ARATH", "id": "Q9STY7-1", "name": "11-beta-hydroxysteroid dehydrogenase-like 3", "aln": "-------------------------------------------MDILTTILNLLLPPLTIIFLFLFYPFYLLIKLVLCLRKNLHFENVARKVVLITGASSGIGEHVAYEYAKKGAYLALVARRRDRLEIV----------------------AETSRQLGSGNVIIIPGDVSNVEDCKKFIDETIRHFGKLDHLINNAGVFQTVLFEDFTQIQDANPIMDINFWGTTYITYFAIPHLRKSKGKIVAITSGSANIPLPLASIYAASKAALLRFFETLRIELSP---DIKITIVLPGVVSTDMTTPHCIEKYGSDFILSESVSKCAKAIFRG--IGRGETYIEEPSWMKWLFIMKNVCPEIVDYGLNYLFVSYLKPYFKRD", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *:* * : : :*. .:::: * : * *::****.***..:**. :: **:: :.** . *: * .. . **:... :.* :.:: .::: : .* ** ** * : : : :: . :::*: . . :: *:* *::: *.*. ::* :.:: *: *:*:* ** **.::* * ::.**: : *.:.*: : . .* :** *::* : : *.* ::: : .::: * : ", "identical_positions": 60, "similar_positions": 106, "identity": "15.83%" }, { "cls_id": "homologset.oma.827636", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q05A13-1", "uniprot_id": "S16C6_MOUSE", "id": "Q05A13-1", "name": "Short-chain dehydrogenase/reductase family 16C member 6", "aln": "-----------------MNSVADTAIFFGKFLYYFLESLVFKVIPK---RKKDVSGEIVLITGAGSGLGRLLAIHFASHGATLVLWDINQEGNMETCRLVKQKGDVKVFAYKCDCSSRIEVYRVADQVKEEVGDVTILINNAGVVTGKSFLNTPDHLVEKSFLVNAISHFWTCKAFLPAMVKANHGHLVCISSIAGLVGINGLSDYSSSKFAAFGFAESLFLELTMIMKTKVKSTIVCPYFIKTGMFEGCTTKYPLLLPLLEQEYVAQKIFNAILEEQVYLIIPKFAYVALFLKQIISPKMMIALG-EYLGVDTCMTSFTGRVKAEELQMETKRKEQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A452DKG3-1", "uniprot_id": "A0A452DKG3_BOVIN", "id": "A0A452DKG3-1", "name": "", "aln": "-----------------MNVLLDTSIFLGKFLYYFLESLYYKIIPK---KKKDVTGEIVLITGAASGLGRLLAIKFASLGAILVLWDINEEGNMETCRMIKEERDAKVFAYTCDCSNRQDVYRVADQVKKEVGNVTILINNAGVVTGREFLKTPDHMVERSFLVNVMSHFWTYKAFLPAMLEANHGHLVCISSFAGIVGINELSDYCASKFAAYGFAESLHFELKLLQKSKINTTIVCPYFIKTGMFEGCSTKYPLLLPMLTQEYAAQSILNAILEEQLYLIMPRFSHVALFLKQIISTNMMMTMA-EYLGMDISLASFIEREKSGEVQTKTEGKQQ", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q9VR28-1", "uniprot_id": "Q9VR28_DROME", "id": "Q9VR28-1", "name": "Short-chain dehydrogenase/reductase family 16C member 6", "aln": "MTASPGLLHMDQPLRAIYQFLLDLLVFTIKSVYYVLESIYYSLLPQRFRKLKDISGQVVLITGGGGGVGRLIALNFARLQARIVIWDINQEAIKTTVDLLAKHGYDNCKGYVVDISDREQIYQRASQVTEEVGPVDILINNAGIVCCKPFWELHDRVIQNTYNINIISHYWTVKAFLPHMMRNNRGHIVTVGSVTGMLGTYGCSDYAATKYACIGFHESLLTDLKAHGYDQIQMSLICPYYINTGMFSGVR---PRMMPMLEPQYVADRIENAVRCNEVWCVLPNSIRLLTPLKCLLPAKMCWELMSRVIRGPESMMMFQGRGRVAAG---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * :* * :**.***: :.::*: : **::*::*****...*:***:*::** * :*:****:*. * :: :. : .* * *.* ::*: *.**.:*** * *******:* : * : *::::.:: :* :**:** ***** *:. *:**:* :.*.:*::* ***.::*:*. ** *** :*. ::: :::***:*:****.* * ::*:* :*.*: * **: :::: ::*. : ** ::..:* : . : .: * * : ", "identical_positions": 106, "similar_positions": 105, "identity": "31.45%" }, { "cls_id": "homologset.oma.827649", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NEX9-1", "uniprot_id": "DR9C7_HUMAN", "id": "Q8NEX9-1", "name": "Short-chain dehydrogenase/reductase family 9C member 7", "aln": "MAALTDLSFMYRWFKNCNLVGNLSEKYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEEGSQKLQRDTSYRLQTTLLDVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIEVTLHMLPMVKRARGRVVNMSSSGGRVAVIGGGYCVSKFGVEAFSDSIRRELYYFGVKVCIIEPGNYRTAILGKENLESRMRKLWERLPQETRDSYGEDYFRIYTDKLKNIMQVAEPRVRDVINSMEHAIVSRSPRIRYNPGLDAKLLYIPLAKLPTPVTDFILSRYLPRPADSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4IFM3-1", "uniprot_id": "DR9C7_BOVIN", "id": "A4IFM3-1", "name": "Short-chain dehydrogenase/reductase family 9C member 7", "aln": "MAAISDLSFMYRWFKNCNLVRNLSDKYVFITGCDSGFGNLLARQLVDRGMRVLAACFTKEGAQKLQQDTSYQLQTILLDVTKTESIKAATQWVRDQVGEQGLWALVNNAGVGLPSGPNEWLTKEDFVKVINVNLVGLIEVTLHMLPMVKKARGRVVNMSSSGGRVAVIGGGYCISKFGVEAFSDSIRRELHYFGVKVSIIEPGNFRTAILGKDGLEKHMRKLWERLPPETRESYGEEYFRIYTDNLKSTMQLADPRISEVTNSMEHAIVSRSPRIRYNPGLDAKLLYLPLAKFPTPVTDFILSRYLPRPADSV", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A8C2M5R5-1", "uniprot_id": "A0A8C2M5R5_CRIGR", "id": "A0A8C2M5R5-1", "name": "", "aln": "MAALTDFSFMYRWFKNCNLVRNLSEKYVFITGCDSGFGNLLARQLVDRGMRVLAACLTEEGAQKLQQETSYQLQTILLDVTKTESIKAAAQWVRDQVGEQGLWALVNNAGVALPSGPNEWLTKEDFVKVINVNLVGLIEVTLNMLPMVKKARGRVVNMSSSGGLVAVIGGGYCVSKFGVEAFSDSIRRELHFFGVKVSIIEPGNYRTSILGHEALQSRMKKLWDRLPQETRDSYGEEYFQVYTEKLVNLMQLAHPKISDVTNSMEHAVVSRSPRIRYNPGLDVKLLYIPLAKLPTSVTDFILSRYLPRPADSV", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***::*:************* ***:*****************:*******:*****:*:**:****::***:*** ******:******:*****:***************.***********:******************:******:************* *********:****************::*****.******:**:***:: *:.:*:***:*** ***:****:**::**::* . **:*.*:: :* ******:**************.****:****:**.*****************", "identical_positions": 255, "similar_positions": 49, "identity": "81.47%" }, { "cls_id": "homologset.oma.827661", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VZ19-1", "uniprot_id": "Q9VZ19_DROME", "id": "Q9VZ19-1", "name": "", "aln": "MERWQNRVAVVTGASSGIGSAIAKDLVLAGMTVVGLARRVDRVKELQRELPAEKRGKLFALYCDVGNESSVNEAFDWIIQKLG-AIDVLVNNAGTLQPGYLVDMNPAVMQQVLQTNIMGIVLCTQRAVRSMRERKFDGHVVLINSILGHKTMTATEGVAPDVNVYPPSKHAVTALAEGYRQEFFGLGTRIKITSVSPGVVDTEIVP------------DSIREAIKDRMLHSEDIAQGVLYAIATPPHVQVHELIIKPLGETM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q54PT0-1", "uniprot_id": "Q54PT0_DICDI", "id": "Q54PT0-1", "name": "", "aln": "-MDYSKKLCVITGASSGFGEALAKILSKSGYSLLLLARRIEKMQEFN--LPN-----CICQKVDVTNYDEFEKAVREAESFFGCKTDLMVNNAGVMLLGHIWEQDMKDWDKTLDVNVKGVLHGCRIVLKDMMDR-NGGTIINVSSIAGLDPYELHS-------VYGASKYGVHCISNTIRKEVAQKN--VRVMIISPGIAETELLSHNKSNEKVFNTYNSWKDTLKGQSMNPYNVANSIKFMYEMPQEITIRDLIICPTKQE-", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:::.*:******:*.*:** * :* ::: ****:::::*:: ** :. ** * ...::*. . :* *::*****.: *:: : : ::.*:.*: *:: : .::.* :* .* :: :.** * .. . ** .**:.* .::: *:*. . ::: :***:.:**::. :* ::::*.: ::. ::*:.: : * .: :::*** * : ", "identical_positions": 61, "similar_positions": 103, "identity": "23.19%" }, { "cls_id": "homologset.oma.827678", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IZV5-1", "uniprot_id": "RDH10_HUMAN", "id": "Q8IZV5-1", "name": "Retinol dehydrogenase 10", "aln": "MNIVVEFFVVTFKVLWAFVLAAARWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGNGEEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPDYCVKQAMKAILTDQPMICTPRLMYIVTFMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8HZT6-1", "uniprot_id": "RDH10_BOVIN", "id": "Q8HZT6-1", "name": "Retinol dehydrogenase 10", "aln": "MNIVVEFFVVTFKVLWAFVLAAARWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGNGEEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPDYCVKQAMKAILTDQPMICTPRLMYIVTFMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q80ZF7-1", "uniprot_id": "RDH10_RAT", "id": "Q80ZF7-1", "name": "Retinol dehydrogenase 10", "aln": "MNIVVEFFLVTFKVLWAFVLAAARWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGNGEEEILPPCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPDYCVKQAMKAILTDQPMICTPRLMYIVTFMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCH7-1", "uniprot_id": "RDH10_MOUSE", "id": "Q8VCH7-1", "name": "Retinol dehydrogenase 10", "aln": "MNIVVEFFVVTFKVLWAFVLAAARWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGKGEEEILPPCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPDYCVKQAMRAILTDQPMVCTPRLMYIVTFMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1D5PLZ3-1", "uniprot_id": "A0A1D5PLZ3_CHICK", "id": "A0A1D5PLZ3-1", "name": "NADP-retinol dehydrogenase", "aln": "MNILLELFVVTFRVLWAFVLAAAKWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYR--ELAEAAPKVAGDGEKDALPHCSLQVYTYTCDVGKRENVYTTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPKMLEMNHGHIVTVASSLGLFSTAGVEDYCASKFGAVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPEYCVKQAMRAILTDQPMICTPRLMYMVTFMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***::*:*:***:**********:************************************************************* * *:**. **.**:: ** *.***:************* *******************************************************.***:*****************************.****************************************************:*******:********:*******:**********************************************", "identical_positions": 313, "similar_positions": 20, "identity": "91.79%" }, { "cls_id": "homologset.oma.827698", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P51661-1", "uniprot_id": "DHI2_MOUSE", "id": "P51661-1", "name": "11-beta-hydroxysteroid dehydrogenase type 2", "aln": "MERWP-WPSGGAWLLVAARALLQLLRSDLRLGRPLLAALALLAALDWLCQRLLPPPAALVVLAGAGWIALSRLARPPRLPVATRAVLITGCDTGFGKETAKKLDAMGFTVLATVLDLNSPGALELRDLCSPRLKLLQMDLTKAEDISRVLEITKAHTASTGLWGLVNNAGLNIVVADVELSPVATFRKCMEVNFFGALELTKGLLPLLRHSRGRIVTVGSPAGDMPYPCLAAYGTSKAAIALLMDTFGCELLPWGIKVSIIKPGCFKTDAVTNVNLWEKRKQLLLANIPRELLQAYGEDYIEHVHGQFLNSLRMALPDLSPVVDAIIDALLAAQPRSRYYPGRGLGLMYFIHHYLPEGLRRCFLQNFFINHLLPRALRPGQHG----------------PAPA----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50233-1", "uniprot_id": "DHI2_RAT", "id": "P50233-1", "name": "11-beta-hydroxysteroid dehydrogenase type 2", "aln": "MERWP-WPSGGAWLLVAARALLQLLRSDLRLGRPLLAALALLAALDWLCQRLLPPPAALVVLAGAGWIALSRLARPPRLPVATRAVLITGCDTGFGKETAKKLDAMGFTVLATVLDLNGPGALELRARCSPRLKLLQMDLTKPEDISRVLEITKAHTASTGLWGLVNNAGLNMVVADVELSPVVTFRECMEVNFFGALELTKGLLPLLRHSRGRIVTVGSPAGDMPYPCLAAYGTSKAAIALLMDTFSCELLPWGIKVSIIQPGCFKTEAVTNVNLWEKRKQLLLANLPRELLQAYGEDYIEHLHGQFLNSLRMALPDLSPVVDAIIDALLAAQPRSRYYTGRGLGLMYFIHHYLPGGLRRRFLQNFFISHLLPRALRPGQPGPV------HDTTQDPNPSPTVSAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P80365-1", "uniprot_id": "DHI2_HUMAN", "id": "P80365-1", "name": "11-beta-hydroxysteroid dehydrogenase type 2", "aln": "MERWP-WPSGGAWLLVAARALLQLLRSDLRLGRPLLAALALLAALDWLCQRLLPPPAALAVLAAAGWIALSRLARPQRLPVATRAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSPGAIELRTCCSPRLRLLQMDLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVSIIQPGCFKTESVRNVGQWEKRKQLLLANLPQELLQAYGKDYIEHLHGQFLHSLRLAMSDLTPVVDAITDALLAARPRRRYYPGQGLGLMYFIHYYLPEGLRRRFLQAFFISHCLPRALQPGQPGTTPPQDAAQDPNLSPGPSPAVAR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8V0ZJ84-1", "uniprot_id": "A0A8V0ZJ84_CHICK", "id": "A0A8V0ZJ84-1", "name": "11-beta-hydroxysteroid dehydrogenase type 2", "aln": "MERAERWAYGALWAALGGGLALRAARGDVVLGRALAVPLALLAAVQSLCRACLPLPLGLALAAASACLLLRWAPGRRLLPVEGRAVLVTGCDSGFGQATARHLDSLGFRVFASVLDPRGPGAQELQRSCSARLTLLRMDLTKPEDIQSVLQHIQAHTNGTGLWGLVNNAGFNDIIADAELSPLGNFRTCMEVNFFGSLELTKGLLPLLRSAGGRIVTVSSPAGDLPFPCLAAYGASKAALSLLMDTFRSELQPWGVKVSLILPGYFKT-ATCDPDFWKLQKEQLVARLPRELLQAYGEDYVEEINRQFIQFMKVAVEDLSAVVNSITDGLLAANPAVRYYPGQGLGLMYFIHRYLPYFVRDLFLRGLFINPKLPRALRPEHKDAK---------------KP-----", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *. *. * :.. *: *.*: ***.* ..******:: **: ** * .*.: *.:. : * . *** ****:****:***: **::**::** *:*:**: ..*** **: **.** **:*****. **. **: :*** .*********** * ::**.****: .** ********:************ : ******.*****:*:***.***:****::****** .** ***:***:* ** *** :. : . *: :*: *:*.:*:*******:**:*.:: **:: :::*: **:.**::* *.****.* ***.*:********* *** :* **: :**. *****:* : . * ", "identical_positions": 213, "similar_positions": 96, "identity": "52.33%" }, { "cls_id": "homologset.oma.827705", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q7Z5J1-1", "uniprot_id": "DHI1L_HUMAN", "id": "Q7Z5J1-1", "name": "Hydroxysteroid 11-beta-dehydrogenase 1-like protein", "aln": "---MKV---LLLTGLGALFFAYYWDD-NFDPAS----------LQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRAR-SPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRSSTS---RPRQPEHRGVPLQSQT-AMFLPPTVPGARTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVRRLCRGLARPHLFGHD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PUF3-1", "uniprot_id": "DHI1L_DANRE", "id": "Q6PUF3-1", "name": "Hydroxysteroid 11-beta-dehydrogenase 1-like protein", "aln": "---MKLYAKLLLCSICVAFIAVRWSAPSFNEES----------LKGARVLVTGASTGIGEQLAYHYARLGAQIVITARRGNVLEQVVSKCREMGAQKAFYIPADMANPSDADLVVKYAIEQLGGLDYLVLNHIGPSPYQMWDG-DVQHTRWLLEVNFLSYLQMAQKALPTLEKSKGSIVVVSSLLGKICGPFALPYASTKFALNGFFGGLQNELAMQKSNVSITICILGLIDTDSAMEKIKGYIN---MTAYPSHEAALQIIQAGATRQSESFYPWYTFYATLFRDWFP------YLRDKVIQNSYTYNP---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9STY8-1", "uniprot_id": "HSD2_ARATH", "id": "Q9STY8-1", "name": "11-beta-hydroxysteroid dehydrogenase-like 2", "aln": "MDMLHTILNFLLPPLTISFLVLFYPFYLFTKLMSCLKHLHFENVTGKVVLITGASSGIGEHVAYEYAKKGAKLALVARRKDRLEIVAETSRQLGSGDVIIIPGDVSNVEDCKKFIDETIHHFGKLDHLINNAGVPQTVIFEDFTQIQDANSIMDINFWGSTYITYFAIPHLRKSKGKIVVISSATAIIPLQAASVYSASKAALVKFFETLRVEISP---DIKITIALPGFISTDMTTPQFKEMYGSDFILSESVSRCAKAIFRGIGRGEAYVIEPSWIKWIFLIKNVCP--EIVDYLLDYIFVS--YLKPYFKRD----------------------", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :** : *:. : * : * **:***.:*:**.:**.**: *:::.:.*: *: *. ..*::*: ..: *..*::. . . .:. ::.::* **:*: * . . * :. ::::** . :: *:* * .***.:**:** . : : *:::* ** ** *: *: :: **:.: *: . : .: . . . . : . . . ::. . . :* ", "identical_positions": 55, "similar_positions": 98, "identity": "16.32%" }, { "cls_id": "homologset.oma.827711", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A6NNS2-1", "uniprot_id": "DRS7C_HUMAN", "id": "A6NNS2-1", "name": "Dehydrogenase/reductase SDR family member 7C", "aln": "MGVMAMLMLPLLLLGISGLLFIYQEVSRLWSKSAVQNKVVVITDAISGLGKECARVFHTGGARLVLCGKNWERLENLYDALISVADPSKQTFTPKLVLLDLSDISCVPDVAKEVLDCYGCVDILINNASVKVKGPAHKISLELDKKIMDANYFGPITLTKALLPNMISRRTGQIVLVNNIQGKFGIPFRTTYAASKHAALGFFDCLRAEVEEYDVVISTVSPTFIRS------------YHVYPEQGNWEASIWKFFFRKL-TYGVHPVEVAEEVMRTVRRKKQEVFMANPIPKAAVYVRTFFPEFFFAVVACGVKEKLNVPEEG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1RMJ5-1", "uniprot_id": "DRS7C_BOVIN", "id": "Q1RMJ5-1", "name": "Dehydrogenase/reductase SDR family member 7C", "aln": "MGVTAVLMLPLLLLGISGLLFIYQEVSRLWSKSVVQNKVVVITDAISGLGKECARVFHTGGARLVLCGKNWERLQSLYDALISVADPSK-TFTPKLVLLDLSDISCVQDVAKEVLDCYGCVDILINNASVKVKGPAHKISLELDKKIMDANYFGPIILTKALLPDMISRRTGQIVLVNNIQGKLGIPFRTAYAASKHAALGFFDCLRAEVEEYDVVVSTVSPTFIRS------------YHVDPGQGNWEASIWKFFFRKL-TYGTHPVDVAEEVMRTVRRKKQEVFLANPIPKAAVYIRTLFPELFFAVVACGVKEKLSVPEEG", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "D3ZGP9-1", "uniprot_id": "DRS7C_RAT", "id": "D3ZGP9-1", "name": "Dehydrogenase/reductase SDR family member 7C", "aln": "MGIMAVLMLPLLLLGVSGLLFIYQEASRLWSKSAVQNKVVVITDALSGLGKECARVFNAGGARLVLCGKNWEGLESLYAALTSVADPSK-TFTPKLVLLDLSDISCVEDVAKEVLDCYGCVDILINNASVKVKGPAHKISLELDKKIMDANYFGPITFTKVLLPNMISRRTGQIVLVNNIQAKFGIPFRTAYAASKHAVMGFFDCLRAEVEEYDVVVSTVSPTFIRS------------YQAYPEQRNWGSSICKFFCRKL-TYGVHPVEVAEEVMRTVRRKKQEVFMANPVPKAAVFIRTFFPELFFAVVACGVKEKLSVPEEG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CHS7-1", "uniprot_id": "DRS7C_MOUSE", "id": "Q8CHS7-1", "name": "Dehydrogenase/reductase SDR family member 7C", "aln": "MGLMAVLMLPLLLLGISGLLFIYQEASRLWSKSAVQNKVVVITDAISGLGKECARVFHAGGARLVLCGKNWEGLESLYATLTSVADPSK-TFTPKLVLLDLSDISCVQDVAKEVLDCYGCVDILINNASVKVKGPAHKISLELDKKIMDANYFGPITLTKVLLPNMISRRTGQIVLVNNIQAKFGIPFRTAYAASKHAVMGFFDCLRAEVEEYDVVVSTVSPTFIRS------------YRASPEQRNWETSICKFFCRKL-AYGVHPVEVAEEVMRTVRRKKQEVFMANPVPKAAVFIRTFFPEFFFAVVACGVKEKLNVPEEG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8E5C5-1", "uniprot_id": "DS7CA_DANRE", "id": "A8E5C5-1", "name": "Dehydrogenase/reductase SDR family member 7C-A", "aln": "MAVPSVMVLPLLIVVFAGVYYVYNEVMRFMSKSVVRNKVVVITDAVSGMGSECARLFHAGGARLVLCGPSWDKLESLYDSLCSGSDPSQ-TFTPKLVLLDFSDMENISDVVSEICECYGCVDVLICNSSMKVKAPVQNLSLEMDKTIMDVNYFGPITLAKGVLPLMITRRTGQFVLVNSIQGKLALPFRTCYAASKHAVQAFFDCLRAEVEEFGISVSTISHTFINAGAENATPTEATPITATPTKATPTNPIWAYVCSKLNTHGVSPQILAQEIVRSVNRQSREVFLAHPVPTVALYIRALMPGCFFSVVSAGVRDGAMAEQLK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: ::::****:: .:*: ::*:*. *: ***.*:*********:**:*.****:*::********* .*: *:.** :* * :***: **********:**:. : **..*: :******:** *:*:***.*.:::***:**.***.****** ::* :** **:*****:****.**.*:.:**** *******. .***********:.: :**:* ***.: . * : . .* :. ** ::*. * :*:*::*:*.*:.:***:*:*:*..*:::*:::* **:**:.**:: . : ", "identical_positions": 162, "similar_positions": 105, "identity": "49.85%" }, { "cls_id": "homologset.oma.827770", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O75452-1", "uniprot_id": "RDH16_HUMAN", "id": "O75452-1", "name": "Retinol dehydrogenase 16", "aln": "MWLYLAVFVGLYYLLHWYRERQVLSHLRDKYVFITGCDSGFGKLLARQLDARGLRVLAACLTEKGAEQLRGQTSDRLETVTLDVTKTESVAAAAQWVKECVRDKGLWGLVNNAGISLPTAPNELLTKQDFVTILDVNLLGVIDVTLSLLPLVRRARGRVVNVSSVMGRVSLFGGGYCISKYGVEAFSDSLRRELSYFGVKVAMIEPGYFKTAVTSKERFLKSFLEIWDRSSPEVKEAYGEKFVADYKKSAEQMEQKCTQDLSLVTNCMEHALIACHPRTRYSAGWDAKLLYLPMSYMPTFLVDAIMYWVSPSPAKAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CGV4-1", "uniprot_id": "Q8CGV4_MOUSE", "id": "Q8CGV4-1", "name": "", "aln": "MWLYLVALVGLWTLLRFFRERQVVSHLQDKYVFITGCDSGFGNLLARQLDRRGMRVLAACLTEKGAEELRNKTSDRLETVILDVTKTESIVAATQWVKERVGNRGLWGLVNNAGISTPSGPNEWMKKQDFARVLDVNLLGMIEVTLSMLPLVRKARGRVVNVSSVMGRMSFFGGGYCISKYGVEAFSDSLRRELSYFGVKVAIIEPGGFKTCVTSSDRLSSNTKMIWDKASSEVKEIYGEKFLLFYLKNLNELDKRCNKDLSVVTDCMEHALTACHPRTRYSAGWDAKFLFLPLSYLPTFLVDALLYWTSMKPEKAL", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****..:***: **:::*****:***:**************:******* **:*************:**.:******** ********:.**:***** * ::************ *:.*** :.****. :*******:*:****:*****:**************:*:*******************************:**** ***.***.:*: .. ***::*.**** *****: * *. ::::::*.:***:**:****** ***************:*:**:**:*******::**.* .* ***", "identical_positions": 235, "similar_positions": 61, "identity": "74.13%" }, { "cls_id": "homologset.oma.827778", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZMP5-1", "uniprot_id": "A0A8I5ZMP5_RAT", "id": "A0A8I5ZMP5-1", "name": "", "aln": "MLRFTRVLPQSKDGTSVSSPRAALQAGRGQQEDTGVSSMKPNFSGLRALVTGAGKGIGRDTAKALHASGAKVVAVTRTNADLVSLAKECPGIEPVCVDLGDWEATEKALGGIGPVDLLVNNAGVALLQPFIESTKEIFDRSFNVNVRAVLQVSQIVAKGMINRGVAGSIVNISSMVAYVTYPGLTTYCSTKGAITMLTKAMAMELGPHKIRVNSVNPTVVLTDMGKKVSADPKFAKKLLKRHPLRKFAEVEDVVNSILFLLSDSSASTTGSGILVDSGYLAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3GXD1-1", "uniprot_id": "G3GXD1_CRIGR", "id": "G3GXD1-1", "name": "", "aln": "--------------------------------------MKLSFSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNADLVSLAKECPGIEPVCVDLGDWEATEKALRNIGPVDLLVNNAGVALVQPFIESTKEVFDRSFNVNVRSVLQVSQVVAKGMISRGVAGSIVNISSMVAYVTFPGLTTYSSTKGALTMLTKAMAMELGPHKIRVNSVNPTVVLTDMGKKVSADPNFAKKLKERHPLRKFAEVEDVVNSILFLLSDSSASTTGSSILVDAGYLAS", "tax_id": 10029, "tax_name": "Chinese hamster" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** .*******************.*********************************************** .***************:*********:**********:******:******.******************:******.*****:**************************************:***** :*******************************.****:*****", "identical_positions": 226, "similar_positions": 15, "identity": "80.14%" }, { "cls_id": "homologset.oma.827786", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q58NB6-1", "uniprot_id": "DHRS9_MOUSE", "id": "Q58NB6-1", "name": "Dehydrogenase/reductase SDR family member 9", "aln": "---MLFWLLALLFLCAFLWNYKGQ--LKIADIADKYVFITGCDTGFGNLAARTFDKKGFRVIAACLTESGSAALKAKTSERLHTVLLDVTDPENVKKTAQWVKSHVGEKGLWGLINNAGVLGVLAPTDWLTVDDYREPIEVNLFGLINVTLNMLPLVKKARGRVINVSSIGGRLAFGGGGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLFKTELADPIKTTEKKLAIWKHLSPDIKQQYGEGYIEKSLHR-LKSNTSSVNLDLSLVVGCMDHALTSLFPKTRYIAGKDAKTFWIPLSHMPAVLQDFLLLKQKVELANPKAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VD48-1", "uniprot_id": "DHRS9_RAT", "id": "Q8VD48-1", "name": "Dehydrogenase/reductase SDR family member 9", "aln": "---MLLWVLALLFLCAFLWNYKGQ--LKIADIADKYIFITGCDSGFGNLAARTFDRKGFRVIAACLTESGSEALKAKTSERLHTVLLDVTNPENVKETAQWVKSHVGEKGLWGLINNAGVLGVLAPTDWLTVDDYREPIEVNLFGLINVTLNMLPLVKKARGRVINVSSIGGRLAFGGGGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLFKTGLADPIKTTEKKLAIWKHLSPDIKQQYGEGYIEKSLHR-LKSSTSSVNLDLSLVVECMDHALTSLFPKTRYTAGKDAKTFWIPLSHMPAALQDFLLLKEKVELANPQAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3GU84-1", "uniprot_id": "G3GU84_CRIGR", "id": "G3GU84-1", "name": "", "aln": "MLLLLFWVSALLVLCAFLWNYKGQ--LKIADITDKYVFITGCDTGFGNLAARTFDKKGFRVIAACLTESGSTALKATASERLHTVLLDVTNPENVKKTAQWVKSHVGEKGLWGLINNAGVLGVLAPTDWLTVNDYREPIEVNLFGLIDVTLNMLPLVKKARGRVINVSSIGGRLAFGGGGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLFKTQLADPIKTTEKKLAVWKHLSPDIKQQYGEGYIEKSLHK-LKSNTSFVNLDLSLVVECMDHALTSVFPKTRYTAGKDAKTFWIPLSHMPAFLQDFLLLKQKVELANPKAV", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q8HYR6-1", "uniprot_id": "DHRS9_BOVIN", "id": "Q8HYR6-1", "name": "Dehydrogenase/reductase SDR family member 9", "aln": "---MLFWLLVLLILCGFLWNYKRQ--LKIANITDKYIFITGCDTGFGNLAARTFDKKGFHVIAACLTESGSTALKAETSERLHTVLLDVTDPENVKRAAQWVKNQVGEKGLWGLINNAGILGVLAPNDWLTVEDYREPVEVNLFGLISVTLNMLPLVKKARGRIINVSSIGGRLAFGGGGYSPSKYAVEGFNDSLRRDMKAFGVHVACIEPGLFKTNLSDPEKTAEKKLAIWKHLSPDIKQQYGESYIEKSLEQ-LKGTASFVNVDLSLVVECMDHALTSLFPKTRYAAGKDAKTFWIPLSHMPAVLQDFLLLKQKVELANPRAV", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A4X1VKJ7-1", "uniprot_id": "A0A4X1VKJ7_PIG", "id": "A0A4X1VKJ7-1", "name": "", "aln": "---MLFWLLALLILCGFLWNYKRQ--LKIADITDKYIFITGCDTGFGNLAARTFDKKGFHVIAACLTESGSTALKAETSERLHTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGILGVLAPTDWLTVEDYREPIEVNLFGLINVTLNMLPLVKKARGRVINVSSIGGRLAFGGGGYAPSKYAVEGFNDSLRRDMKAFGVHVACIEPGLFKTGLADPVKTAEKKLAIWNHLSPDIRQQYGEGYIEKCLSK-LKGSKSFMNVDLSLVVECMDHALTSLFPKTRYAAGKDAKTFWIPLSHMPAVLQDFLLLKQKVELANPRAV", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q9BPW9-1", "uniprot_id": "DHRS9_HUMAN", "id": "Q9BPW9-1", "name": "Dehydrogenase/reductase SDR family member 9", "aln": "---MLFWVLGLLILCGFLWTRKGK--LKIEDITDKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAETSERLRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGGGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLFKTNLADPVKVIEKKLAIWEQLSPDIKQQYGEGYIEKSLDK-LKGNKSYVNMDLSPVVECMDHALTSLFPKTHYAAGKDAKIFWIPLSHMPAALQDFLLLKQKAELANPKAV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1C781-1", "uniprot_id": "E1C781_CHICK", "id": "E1C781-1", "name": "", "aln": "---MFFYILLFLSISSLWWYWKTRDGGKVANLNGKYIFITGCDTGFGNMAAKTFDKKGFRVLASCLTETGAKELQAATSDQLQTVLLDVRDSNSVKKAAAWIKAKVQSEGLWGLVNNAGIMGPTAPTDWLDIEHFREPIEVNLIGLINVTINMLPLIKLAKGRIVNVSSIGGRLAFCGGGYCPSKFGVEGFNDSLRRDMKAFGVKVSCIQPGLFKTPLTDLAKILKEKEVIWNRLPPDTKKQYGEEYFQKEAAKKEKFSKACLNTDISLVVECMEHALTSLHPRAHYVVGQDAKWFWTPLSRMPADVQDFLLLGNREKPAVSHRK", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::::: :* :..: * * : *: :: .**:******:****:**:***:***:*:*:****:*: *:* :*::*:****** :.:.**.:* *:* :* .:*****:****: * **.*** ::.:***:****:***.**:*****:* *:**::****:*****: **** ***:.*****************:*:**:****** *:* * ::* .:*::*.** ::**** *::* : * . : :* *:* ** **:*****:.*:::* .*:*** ** ***:*** :****** :: : * .: ", "identical_positions": 173, "similar_positions": 94, "identity": "53.23%" }, { "cls_id": "homologset.oma.827819", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "G5E8H9-1", "uniprot_id": "G5E8H9_MOUSE", "id": "G5E8H9-1", "name": "", "aln": "MWLYLVSLVGLWTLLRFFRERQVVSHLQDKYVFITGCDSGFGNLLARQLDRRGMRVLAACLTEKGAEELRNKTSDRLETVILDVTKTESIVAATQWVKERVGNRGLWGLVNNAGISVPLGLSQWMNKQNFASVLDVNLLGMIEVTLTMLPLVRKARGRVVNVSSIMGRVSLHGNGGYCISKYGVEAFSDSLRRELSYFGVKVAIIEPGFFLTGMASSARLSSNTQMLWDQTSSEIREIYGEKYL---AFYLKSLNELDKRCNKDLSLVTDCMEHALTACHPRTRYSAGWDAKLFFIPLSYLPTFLVDAVFYWTSMKPEKAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55006-1", "uniprot_id": "RDH7_RAT", "id": "P55006-1", "name": "Retinol dehydrogenase 7", "aln": "MWLYLLALVGLWNLLRLFRERKVVSHLQDKYVFITGCDSGFGNLLARQLDRRGMRVLAACLTEKGAEQLRSKTSDRLETVILDVTKTESIVAATQWVKERVGNRGLWGLVNNAGISVPMGPNEWMRKKDFASVLDVNLLGVIEVTLNMLPLVRKARGRVVNIASTMGRMSLLG-GGYCISKYGVEAFSDSLRRELTYFGVKVAIIEPGGFKTNVTNMERLSDNLKKLWDQATEEVKEIYGEKFR---DSYMKAMESLVNMCSGDLSLVTDCMEHALTSCHPRTRYSAGWDAKFFYLPMSYLPTFLSDAVIYWGSVKPARAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A3Q1LUI1-1", "uniprot_id": "A0A3Q1LUI1_BOVIN", "id": "A0A3Q1LUI1-1", "name": "Retinol dehydrogenase 16-like", "aln": "MWLYLVVLVVLYYLLRWYRERQVVSHLEDKFVFITGCDSGFGNRLARQLDQRGLRVLAACLTEQGAEQLRNQTSDRLQTVILDVTKTENVTATTNWVKEHVGDRGLWGLVNNAGICTPMAPNEWLTKQDFVKVLDVNLLGVIDVTLSLLSLVRKARGRVVNVSS------------YCISKYGVEAFSDSLRRELSYFGVKVAMIEPGYFVTNMTQDEGFIGYLQALWNPASPELKELYGENFPSDATHGIMTLSLLKPRWTQNLSLVTDCMEHALTACHPRTRYSAGWDAKFIYLPMSYLPSFLVDLIVYCYYPQPAKAL", "tax_id": 9913, "tax_name": "Bovine" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****: ** *: *** :***:*****:**:************ ******:**:*********:***:**.:*****:**********.:.*:*:****:**:************..*:. .:*: *::*..********:*:***.:*.***********::* *******************:*******:**** * *.::. : . : **: :: *::*:***:: : ::. * . :*************:**************::::*:****:** * :.* :* :**", "identical_positions": 198, "similar_positions": 72, "identity": "61.68%" }, { "cls_id": "homologset.oma.827828", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P0DKC5-1", "uniprot_id": "HSD1A_ARATH", "id": "P0DKC5-1", "name": "11-beta-hydroxysteroid dehydrogenase 1A", "aln": "MELINDFLNLTAPFFTFFGLCFFLPPFYFFKFLQSIFSTIFSENLYGKVVLITGASSGIGEQLAYEYACRGACLALTARRKNRLEEVAEIARELGSPNVVTVHADVSKPDDCRRIVDDTITHFGRLDHLVNNAGMTQISMFENIEDITRTKAVLDTNFWGSVYTTRAALPYLRQSNGKIVAMSSSAAWLTAPRMSFYNASKAALLSFFETMRIELGGDVHITIVTPGYIESELTQGKYFSGEGELIVNQDMRDVQVGPFPVASASGCAKSIVNGVCRKQRYVTEPSWFKVTYLWKVLCPELIEWGCRLLYMTGTGMSEDTALNKRIMDIPGVRSTLYPESIRTPEIKSD", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "P0DKC6-1", "uniprot_id": "HSD1B_ARATH", "id": "P0DKC6-1", "name": "11-beta-hydroxysteroid dehydrogenase 1B", "aln": "MELINDFLNLTAPFFTFFGLCFFLPPFYFFKFLQSIFSTIFSENLYGKVVLITGASSGIGEQLAYEYACRGACLALTARRKNRLEEVAEIARELGSPNVVTVHADVSKPDDCRRIVDDTITHFGRLDHLVNNAGMTQISMFENIEDITRTKAVLDTNFWGSVYTTRAALPYLRQSNGKIVAMSSSAAWLTAPRMSFYNASKAALLSFFETMRIELGGDVHITIVTPGYIESELTQGKYFSGEGELIVNQDMRDVQVGPFPVASASGCAKSIVNGVCRKQRYVTEPSWFKVTYLWKVLCPELIEWGCRLLYMTGTGMSEDTALNKRIMDIPGVRSTLYPESIRTPEIKSD", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************************************************************************************************************************************************************************************************************************************************************************************************************************************************************", "identical_positions": 349, "similar_positions": 0, "identity": "100.0%" }, { "cls_id": "homologset.oma.827833", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0B4KFB3-1", "uniprot_id": "A0A0B4KFB3_DROME", "id": "A0A0B4KFB3-1", "name": "NADP-retinol dehydrogenase", "aln": "MEIVIRFLQSIAPVFLAHGIVGIIAFCVRLYMQGGKFRKQTDETGKVAIVTGGNTGLGKETVMELARRGATVYMACRNKEKVERARREIVKETGNSNVFSRECDLSSLDSIRKFAENFKKEQRVLHILINNAGVFWEPHRLTKEGFEMHLGVNHIGHFLLTNLLLGVLERSAP-----SRVVVVASRAHERGQ---IKVDDINSSDFYDEGVAYCQSKLANILFTRELAKRL--EGTGVTVNALNPGIADTEIARNMIFFQTKFAQYVVETILRPLLWAVMKTPKNGAQTTLYAALDPDLERVSGQYFSDCALAPVAPAALDDQMAQWLWAQSEKWAKIAL-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A2RVM0-1", "uniprot_id": "TIC32_ARATH", "id": "A2RVM0-1", "name": "Short-chain dehydrogenase TIC 32, chloroplastic", "aln": "--------------MWFFGSKGASGFSSRS--TAEEVTHGVDGTGLTAIVTGASSGIGVETARVLSLRGVHVVMAVRNTDSGAKVKEDIVKQVPGAKLDVMELDLSSMQSVRKFASEYKSTGLPLNLLINNAGIMACPFMLSKDNIELQFATNHLGHFLLTKLLLDTMKSTSRESKREGRIVNLSSEAHRFSYPEGVRFDKINDKSSYSSMRAYGQSKLCNVLHANELTKQLKEDGVNITANSLHPGAIMTNLGR--------YFNPYLAVAVGAVAKYILKSVPQGAATTCYVALNPQVAGVSGEYFQDSNIAKPLPLVKDTELAKKVWDFSTKLTDSQSGESSS", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* * .*. * . :. : .* ** .*****..:*:* **. *: **. * ** **.:. :.:.:***:. .::: * ****::*:****.::*. *::******:: *. *:*:.:*:::..**:******:***..:: :: .*:* ::*.**. . ::.*.**... *.. ** ****.*:*.:.**:*:* :*..:*.*:*:** *::.* : : : . : .: ::*: :** ** *.**:*:: ***:**.*. :* * . * ::*: :* * * :. ", "identical_positions": 111, "similar_positions": 119, "identity": "32.08%" }, { "cls_id": "homologset.oma.827837", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O76752-1", "uniprot_id": "O76752_DROME", "id": "O76752-1", "name": "Sepiapterin reductase", "aln": "---MDLKQRTYLLVTGASRGIGREFAQQLAKRIKAEGSMVTLLGRNQTLLQESKAEIVATVPDLSVQTYSLELETAKTEDFTKILEASGGKNNFERAIVIHNAGTVGDTSKRAKEIGDTDFLQRYYHSNVFSAISLNCEFMRVFK---GIPKLVVNLSTLAAIAPISSMAHYCTVKAAREMYFRVLATEESAEDTLVLNYAPGVIDTQMTVQVQREAHDPAVVAMFREQRESKTMLTPAQTTERFIKVLEAFKFKSGDHVDYRDEQF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "F1QWX4-1", "uniprot_id": "F1QWX4_DANRE", "id": "F1QWX4-1", "name": "Sepiapterin reductase", "aln": "MSTASGFGKALVIITGASRGFGRALALSVAARVSPG-SVLVLAARSEEQLLELKSALTRGETGLTVRCVPVDLG-CEAGVEKLIAETRDIQPDIQHLLLFHNAASLGDVSRYCRDFTNMEELNSYLSLNVSSALCLTAGVLRTYPKRSGLTRVIVNISSLCALRPFPTWVQYCSGKAARDMMFRVLAEEE--PELRVLNYAPGPLDTDMQREARSSCADSELRNTFSQMHANGQLLTCDQSIQKLMSVLLEDKYSSGEHLDYYDL--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: :::******:** :* .:* *:.. *::.* .*.: * * *: :. ..*:*: .::* .:: . * *: . : :::: :::***.::**.*: .::: : : *: * ** **:.*.. .:*.: *:.:::**:*:*.*: *:.: .:**: ****:* ***** ** : ******* :**:* :.: .. *. : * : : . :** *: ::::.** *:.**:*:** * ", "identical_positions": 81, "similar_positions": 103, "identity": "30.34%" }, { "cls_id": "homologset.oma.827965", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O54909-1", "uniprot_id": "RDH16_MOUSE", "id": "O54909-1", "name": "Retinol dehydrogenase 16", "aln": "MWLYLVALVGLWTLLRFFRVRQVVSHLQDKYVFITGCDSGFGTLLARQLDRRGMRVLAACLTEKGAEELRNKTSDRLETVILDVTKTESIVTATQWVKEHVGNRGLWGLVNNAGISTPSGPNEWMKKQDFAHVLDVNLLGMIEVTLSMLPLVRKARGRVVNVSSVMGRVSLFGGGYCISKYGVEAFSDSLRRELSYFGVKVAIIEPGFFLTGVTSSARLCSNTQMLWDQTSSEIREIYGEKYLASYLKRLNKLDKRCNKDLSGVTDCMEHALTACHPRTRYSAGWDAKLFYLPLSYLPTFLVDALLYWTSLKPEKAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A3Q1LTW0-1", "uniprot_id": "A0A3Q1LTW0_BOVIN", "id": "A0A3Q1LTW0-1", "name": "Retinol dehydrogenase 16-like", "aln": "MWLYLAVLLGLYYFLRWYRERQVVSHLRDKFVFITGCDSGFGNQLARQLDLKGLRVLAACLMKQGAEQLRNQTSDRLQTVILDVTKTESVAAATEWVKERVGDRGLWGLVNNAGICTPMAPNQWLTKQDFVKILEVNLLGVIDVTLSLLPLVRKARGHVVNVSSVMGRMAVFGGGYSMSKYGVEAFSDSL--------MKVAVIEPGYFLTDMTQEEVYHENLQTSWDHASPEIQELYGDNFLADFIKASDFLKAPWARNLSLVTNCMEHALTACHPRSRYSAGWDAKFLYLPMSYLPSFLVDLMIYWNYPQPAKAL", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A8V1A759-1", "uniprot_id": "A0A8V1A759_CHICK", "id": "A0A8V1A759-1", "name": "RDH16 dehydrogenase", "aln": "MWLWLLALLGLWLLRRWHRERQTVPGLEEKFVLITGCDSGFGDLLARQLDARGLRVLAGCLTESGAARLRETASSRLQTVLLDVTSSSSIAAAAAWVQERVGERGLWGLVNNAGIAVPAAPNEWLRKEDFVAVLNVNLVGLIEVTLSLLPLVKRARGRVVNVASVMGRLSIFGGGYCPSKFGVEAFSDNLRLEMQHFGVKVSIIEPGYFKTGITNAAALERTLISTWERLSKETKASYGDKYLQDFLASMREMQKKCNPNLSLVTDCMEHALTRCYPRCRYAAGWDAKLLYIPLSYMPSAITDAFFTWLSPKPAQRA", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:* .*:**: : *:.* **.*. *.:*:*:********* ****** :*:****.** :.** .**: :*.**:**:****.:.*:.:*: **:*:**:************..* .**:*: *:**. :*:***:*:*:****:****::***:****:*****:::*****. **:*******.* :**::****:* *.:*. . *:: * * : **:::* .:: :. :** **:******* *:** **:******::*:*:**:*: :.* :: * :* : ", "identical_positions": 162, "similar_positions": 92, "identity": "51.1%" }, { "cls_id": "homologset.oma.827969", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P0DKC5-1", "uniprot_id": "HSD1A_ARATH", "id": "P0DKC5-1", "name": "11-beta-hydroxysteroid dehydrogenase 1A", "aln": "MELINDFLNLTAPFFTFFGLCFFLPPFYFFKFLQSIFSTIFSENLYGKVVLITGASSGIGEQLAYEYACRGACLALTARRKNRLEEVAEIARELGSPNVVTVHADVSKPDDCRRIVDDTITHFGRLDHLVNNAGMTQISMFENIEDITRTKAVLDTNFWGSVYTTRAALPYLRQSNGKIVAMSSSAAWLTAPRMSFYNASKAALLSFFETMRIELGGDVHITIVTPGYIESELTQGKYFSGEGELIVNQDMRDVQVGPFPVASASGCAKSIVNGVCRKQRYVTEPSWFKVTYLWKVLCPELIEWGCRLLYMTGTGMSEDTALNKRIMDIPGVRSTLYPESIRTPEIKSD", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "P0DKC6-1", "uniprot_id": "HSD1B_ARATH", "id": "P0DKC6-1", "name": "11-beta-hydroxysteroid dehydrogenase 1B", "aln": "MELINDFLNLTAPFFTFFGLCFFLPPFYFFKFLQSIFSTIFSENLYGKVVLITGASSGIGEQLAYEYACRGACLALTARRKNRLEEVAEIARELGSPNVVTVHADVSKPDDCRRIVDDTITHFGRLDHLVNNAGMTQISMFENIEDITRTKAVLDTNFWGSVYTTRAALPYLRQSNGKIVAMSSSAAWLTAPRMSFYNASKAALLSFFETMRIELGGDVHITIVTPGYIESELTQGKYFSGEGELIVNQDMRDVQVGPFPVASASGCAKSIVNGVCRKQRYVTEPSWFKVTYLWKVLCPELIEWGCRLLYMTGTGMSEDTALNKRIMDIPGVRSTLYPESIRTPEIKSD", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************************************************************************************************************************************************************************************************************************************************************************************************************************************************************", "identical_positions": 349, "similar_positions": 0, "identity": "100.0%" }, { "cls_id": "homologset.oma.830385", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N9S3-1", "uniprot_id": "AHSA2_MOUSE", "id": "Q8N9S3-1", "name": "Activator of 90 kDa heat shock protein ATPase homolog 2", "aln": "MAKWGQGDPRWIVEEREDGTNVNNWHWTERDATIWSKGKLRELLVGIAMENEAG--RCEISELKQVEGEASCNSRKGKLIFFYEWNIKLAWKG-TVKESG---AKHKGLIEIPSLSEENEINDTEVNVSKKKG--DGEILKDLMRTTGTAKVREALGEYLKALKTEFTTGMILPTK--------------AVATQELTLQRKLNENKLQASP---------VALGVRIPTVALHLTELFDTTVEQLYSIFTVKELVQKFSKSPAVLEAE----RGGKFQMFDGNISGEYVELVTNRKIIMKWRCRNWPEEHYATVELNFVP--APGQTELQLDCKGVP-------VCKEENMKFCWQKQHFEEIKGLLELTAQNA---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K7W5-1", "uniprot_id": "A0A0G2K7W5_RAT", "id": "A0A0G2K7W5-1", "name": "", "aln": "MAKWGQGDPRWIVEEREDGTNVNNWHWTERDATVWSKGKLRELLVGLAMENEAG--RCEISELKQVEGEASCNSRKGKLIFFYEWNIKLAWKG-TVKESG---AKHKGLIEIPSLSEENEVNDTEVNVSKKKG--DGEILKDLMRTTGTAKVREALGEYLKALKTEFTTGMILPTK--------------AGATQALTLERKLTENALQASP---------VALGVRIPTVALHLTELFDTTVEQLYSIFTVKELVQGFSKSPAVLEAE----KGGKFQMFDGNITGEYVELVTNRKIIMKWRCRNWPEEHYATVELNFVP--APGQTELQLDCKGVP-------VCKEEHMKFCWQKQHFEEIKGLLQLTTQNA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E1BSW0-1", "uniprot_id": "E1BSW0_CHICK", "id": "E1BSW0-1", "name": "", "aln": "MAKWGQGDPRWIVEERADGTNVNNWHWTERDATSWSRSKLQEVLVGLVVEGEAG--RCEICELKQVEGEASCSSRKGRLIFFYEWNLRLSWKG-TVKESG---EKHKGSIEIPNLSEENEVDDTEINVSKKKG--EGDILKELMRTEGTTKVREALRDYLKALKTEFTLGMILPTK--------------AAG-QELAAERRLSGNTVQESASPHL----QGLVGVKIPTVRILMREIFSSPADELYSIFTTKELVQKFSKCPAVIEAE----KGGKLLMFDGCVSGEYTELVPGKRLVLKWRCRNWPDEHYATVALNFQN--MVAETELQLECKGVP-------VSNEDSTRQWWKKQYFEEIHNLLQQSKDNMD--", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9V9Q4-1", "uniprot_id": "Q9V9Q4_DROME", "id": "Q9V9Q4-1", "name": "Activator of Hsp90 ATPase AHSA1-like N-terminal domain-containing protein", "aln": "MAKWGEGDPRWIVEERPDATNVNNWHWTEKNATPWSKDRLHQLFQDFKIGQSDI--ECAVDSVDKCSGEATVNNRKGKLIFFYEWELVLKWSGKLLKNSK---LIHKGKLTIPNLSEENELADVEITVTIDESNDESETLKQFMYNVGRDRVRQQLASYIRELKEEYSKNLILPKKGDEA-----GAGNTVANFKDANNTRNAAQNIALNSSVAAPRLK-NSGIGCKLDVRTLSMTEEFHCSANDLYNALTKPEMVTAFTRAPAKVDAV----RGGEFILYGGNVLGKFEELVPEKKIQQSWRLKNWTSGHYSNVVIELEE--TSSSTMMSLKQTGIP-------ASEFDAMKTNWYRYYWHSIKQTFGFGTSISDAL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9LHL7-1", "uniprot_id": "Q9LHL7_ARATH", "id": "Q9LHL7-1", "name": "", "aln": "MAKFGEGDKRWIVEDRPDGTNVHNWHWSETNCLEWSRNFFTKQFSGVDILSGEGNLFIKVSKIEKVEGEAYVNVRKGKIIPGYELNVSLSWEGEAKDSDGKTLLKADGLVDMPYISDENADEDPEIRFSVKDEGPIGRTLKEAMVKKGKEIILEKVRVYVEAMARGGPCRDELESK--KV-----APKSVAAGSATVAVEKSGAAPVVSAAAVESKVVKEKKKAKTKEGFKTITMTEKFNCRARDLYEILMDENRWKGFTQSNAKISKD----VNGPISVFDGSVTGMNLELEEGKLIVQKWRFGSWPDGLDSTVKIVFEEP-QPGVTIVNLTHTDVPEEDRYGNATVVENTERGWRDLIFHRIRAVFGFGI------", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q12449-1", "uniprot_id": "AHA1_YEAST", "id": "Q12449-1", "name": "Hsp90 co-chaperone AHA1", "aln": "-----------MVVNNP-----NNWHWVDKNCIGWAKEYFKQKLVGVEAGSVKDKKYAKIKSVSSIEGDCEVNQRKGKVISLFDLKITVLIEGHVDSKDG-SALPFEGSINVPEVAFDSEASSYQFDISIFKETSELSEAKPLIRSELLPKLRQIFQQFGKDLLATHGNDIQVPESQVKSNYTRGNQKSSFTEIKDSASKPKKNALPSSTSTSAPVSSTNKVPQNGSGNSTSIYLEPTFNVPSSELYETFLDKQRILAWTRSAQFFNSGPKLETKEKFELFGGNVISELVSCEKDKKLVFHWKLKDWSAPFNSTIEMTFHESQEFHETKLQVKWTGIP-------VGEEDRVRANFEEYYVRSIKLTFGFGAVL----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :. :**** : :. *:: : : : .. : .:.. .*:. . ***::* :: :: : .* ... .* : :* :: :. . :. .: . * : . : : . : . : : . :. : : * :**. : : :::. .. : ::.* : . . : : *: .*. :.: : : * :.: ..:* . : . : . *: : ", "identical_positions": 24, "similar_positions": 101, "identity": "6.35%" }, { "cls_id": "homologset.oma.830386", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O95433-1", "uniprot_id": "AHSA1_HUMAN", "id": "O95433-1", "name": "Activator of 90 kDa heat shock protein ATPase homolog 1", "aln": "MAKWGEGDPRWIVEERADATNVNNWHWTERDASNWSTDKLKTLFLAVQVQN-EEGKCEVTEVSKLDGEASINNRKGKLIFFYEWSVKLNWTGTSKSG-----------------------------------VQYKGHVEIPNLSDEN--SVDEVEISVSLAKDEPDTN-----LVALMKEEGVKLLREAMGIYISTLKTEFTQGMILPTMNGESVDPVGQPALKTEERK--AKPAPSKTQARPVGVKIPTCKITLKETFLTSPEELYRVFTTQELVQAFTHAPATLEADRGGKFHMVDGNVSGEFTDLVPEKHIVMKWRFKSWPEGHFATITLTF-IDKNGETELCMEGRGIPAPEEERTRQGWQRYYFEGIKQTFGYGARLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A4X1T4G7-1", "uniprot_id": "A0A4X1T4G7_PIG", "id": "A0A4X1T4G7-1", "name": "Activator of 90 kDa heat shock protein ATPase homolog 1", "aln": "MAKWGEGDPRWIVEERADATNVNNWHWTERDASNWSTDKLKTLFLAVRVQN-EEGKCEVTEVNKLDGEASINNRKGKLIFFYEWSIKLNWTGTSKSG-----------------------------------VQYKGHVDIPNLSDEN--SVDEVEISVSLAKDEPDTN-----LVALMKEEGVRLLREAMGIYISTLKTEFTQGMILPTMNGESVDPAGQPALKTEERK--AKSAPSKTQARPVGVKIPTCKITLRETFLTSPEELYRVFTNQELVQAFTHAPAMLEADKGGKFHLVDGNVSGEFTDLVPEKHIVMKWRFKSWPEGHFATITLTF-IDKNGETELCMEGRGVPAPEEERTRQGWQRYYFEGIKQTFGYGARLF", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "B0BN63-1", "uniprot_id": "B0BN63_RAT", "id": "B0BN63-1", "name": "Activator of 90 kDa heat shock protein ATPase homolog 1", "aln": "MAKWGEGDPRWIVEERADATNVNNWHWTERDASNWSTEKLKTLFLAVRVEN-EEGKCEVTEVNKLDGEASINNRKGKLIFFYEWTIKLNWTGTSKSG-----------------------------------VQYKGHVEIPNLSDEN--SVDEVEISVSLAKDEPDTS-----LVALMKEDGVKLLREAVGIYISTLKTEFTQGMILPTVNGESVDPVGQPALKTEVCK--AKCAPSKSQAKPVGVKIPTCKITLKETFLTSPEELYRVFTTQELVQAFTHAPAALEADRGGKFHMVDGNVTGEFTDLVPEKHIAMKWRFKSWPEGHFATITLTF-IDKNGETELCMEGRGIPAPEEERTRQGWQRYYFEGIKQTFGYGARLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BK64-1", "uniprot_id": "AHSA1_MOUSE", "id": "Q8BK64-1", "name": "Activator of 90 kDa heat shock protein ATPase homolog 1", "aln": "MAKWGEGDPRWIVEERADATNVNNWHWTERDASNWSTEKLKTLFLAVRVEN-EEGKCEVTEVNKLDGEASINNRKGKLIFFYEWTIKLNWTGTSKSG-----------------------------------VQYKGHVEIPNLSDEN--SVDEVEISVSLAKDEPDTN-----LVALMKEDGVKLLREAVGIYISTLKTEFTQGMILPTVNGESVDPVGQPALKTETCK--AKSAPSKSQAKPVGVKIPTCKITLKETFLTSPEELYRVFTTQELVQAFTHAPAALEADRGGKFHMVDGNVTGEFTDLVPEKHIAMKWRFKSWPEGHFATITLTF-IDKNGETELCMEGRGIPAPEEERTRQGWQRYYFEGIKQTFGYGARLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3H638-1", "uniprot_id": "G3H638_CRIGR", "id": "G3H638-1", "name": "Activator of 90 kDa heat shock protein ATPase homolog 1", "aln": "MAKWGEGDPRWIVEERADATNVNNWHWTERDASNWSTEKLKTLFLAVRVEN-EEGKCEVTEVNKLDGEASINNRKGKLIFFYEWTIKLNWTGTSKSG-----------------------------------VQYKGHVEIPNLSDEN--SVDEVEISVSLAKDEPDTN-----LVALMKEEGVKLLREAVGIYISTLKTEFTQGMILPTVNGESVEPVSQPAPKTEVCK--AKSAPSKSQAKPVGVKIPTCKISLRETFLTSPEELYRVFTTQELVQAFTHAPAALEADKGGKFHMVDGNVTGEFTDLVPEKHIAMKWRFKSWPEGHFATITLTF-IDKNGETEVCMEGRGIPAPEEERTRQGWQRYYFEGIKQTFGYGARLF", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "E1C123-1", "uniprot_id": "E1C123_CHICK", "id": "E1C123-1", "name": "Activator of 90 kDa heat shock protein ATPase homolog 1", "aln": "MAKWGEGDPRWIVEQRADATNVNNWHWTERDASNWSTERLKALLLPVRVEG-EEGACEVTEVSKLDGEASINNRKGKLIFFYEWAIKLAWTGTSTTG-----------------------------------VKYKGYVEIPNLSDEN--DVDEVEILVSLAKDEPDTN-----LKTLMKQEGAKKIRDAIKTYISTLKTEFTQGMILPTVNGEHMETAPQVAPKAKDSKTAASSSTATAQSKSIGVKIPTCKIILKDTFLTSPEELYRVFVTQEMVQAFTHAHAALEADKGGKFQLLDGSVTGEFVDLVPEKQLVMKWRFKSWPAGHFATITLNF-TDKGGETEVCLEGKGIPASEEERTKQGWQRYYFEGIKQTFGYGARLF", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q55DB6-1", "uniprot_id": "AHSA_DICDI", "id": "Q55DB6-1", "name": "Activator of 90 kDa heat shock protein ATPase homolog", "aln": "MAKVGEGDPRWIVENREDGHNVNGWHWSEKDCLPWSKNTIGGLFDKKVIQETDEYTFKISSTPVVSGECTANNRKGKTIFLYELDVKMNWEVVFKPKKVLPPPPTTKSKGAADDIDEEDDDGKPAEPIITQKKTISGEFTVPYISDENGDEAPTVRYTINTTADNDETKQSINMVQSLLKSHGVPFVQSQCQEFIKLLKKEFVSKKQVEQSQQQQTANTTTNTTTTTNTVPKVTSSTVIFNSTPT-KKPTTKTLKLKEEFQCSPMDAYDVFVNINKLRAFTQSDCTFENEEGGKFSLYGGSIQGVNKTLSPGSKIVQTWRLDNWSKGVESQVTITFSVDGKPLTNVEIVQTGIPIDEFEKTEEGWKRNILDRIKHTFSYSSKIF", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** **********:* *. ***.***:*:*. **.: : *: :: :* :::.. :.**.: ****** **:** :*: * . .. .* . :* :**** .. *. :. : *: :*. : :*:*..*. ::. :*. **.**.. : : : . : .: .. :. :: . * .* .: *:: * ** : * **.. : ::***:: . :* :.**** : .*.: * * * .::. .**:..*. * : :*:.* * *:: : *:* * *:*.:**:* :: **:**.*.:::*", "identical_positions": 101, "similar_positions": 119, "identity": "26.3%" }, { "cls_id": "homologset.oma.830442", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1P258-1", "uniprot_id": "A0A8M1P258_DANRE", "id": "A0A8M1P258-1", "name": "Low molecular weight phosphotyrosine protein phosphatase", "aln": "MAASS--GKSVLFVCLGNICRSPIAEAVFRKMATDSGVVDKW-RIDSAATSTYEIGNPPDHR-GQACMKKHGVSMR------------HVARQVTKDDFMSFDYILCMDESNLRDLN---KKASSVKNSKAKIELLGSYDPEK---QLIIQDPYYGSDKD-FETVYEQCARCCKAFLEQHS---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5ZKG5-1", "uniprot_id": "PPAC_CHICK", "id": "Q5ZKG5-1", "name": "Low molecular weight phosphotyrosine protein phosphatase", "aln": "MAAGE--VKSVLFVCLGNICRSPIAEAVFRKLVTDEKVENKW-RIDSAATSTYEIGNPPDYR-GQTCMKKHGITMN------------HIARQVTKDDFQTFDYILCMDESNLRDLK---RKSNQVKDCKAKIELLGAYDPQK---QLIIEDPYYGNEKD-FETVYEQCVRCCKAFLEKPH---", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "A0A3Q1N8V6-1", "uniprot_id": "A0A3Q1N8V6_BOVIN", "id": "A0A3Q1N8V6-1", "name": "Low molecular weight phosphotyrosine protein phosphatase", "aln": "MAEQV--TKSVLFVCLGNICQSPIAEAVFRKLVTDQNISDNW-RIDSAATSTYELGNPPDYR-GQACMKKHGIPMS------------HVARQVTKEDFDTFDYILCMDESNLRDMN---RKSNQVKNCRAKIKLLGNYDPQK---QLIIEDPYYGDNAD-FEAVYQQCVRCCRAFLGKVR---", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q55GW2-1", "uniprot_id": "PPAC_DICDI", "id": "Q55GW2-1", "name": "Low molecular weight phosphotyrosine protein phosphatase", "aln": "MSADSKNQKKVLFVCLGNICRSTMAEIVLRGLVHSRGILDDF-QIDSAGTSSYHIGDTPDPRTVQSCNQNMGRAISEESLKHFKSIPLHRARQFTDEDFSKFDYIFAMDESNLSNIKKVLKHSTTKDNHIATIKRLGEYHTHK---KINVEDPYYGDMSN-FNICFNHVHDCLVNFLKEIESLN", "tax_id": 44689, "tax_name": "Social amoeba" }, { "uniprot_ac": "P40347-1", "uniprot_id": "PPAL_YEAST", "id": "P40347-1", "name": "Low molecular weight phosphotyrosine protein phosphatase", "aln": "MTIEKP-KISVAFICLGNFCRSPMAEAIFKHEVEKANLENRFNKIDSFGTSNYHVGESPDHR-TVSICKQHGVKIN------------HKGKQIKTKHFDEYDYIIGMDESNINNLK-----KIQPEGSKAKVCLFGDWNTNDGTVQTIIEDPWYGDIQD-FEYNFKQITYFSKQFLKKEL---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P82890-1", "uniprot_id": "PPAC1_DROME", "id": "P82890-1", "name": "Low molecular weight phosphotyrosine protein phosphatase 1", "aln": "------MVRKVLMICLGNICRSPIAEVVMVDTLEKANVKDVE--VDSAAIGGWHVGNRADPR-AISTLQKHGLKCT------------HIVRQIRKQDFSEFDYIFGMDEDNMSELR-----RLAPKGSKAELLMLGDFGLEKK--NRIIEDPYYERGAEGFETAYQQCVVACAAFMKERLQK-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* ::****:*:*.:** :: . : : :** . . :.:*: .* * : :: * * :*. ..* :***: ***.*: ::. .. * : :* : .. : ::**:* : *: ::: *: : ", "identical_positions": 32, "similar_positions": 52, "identity": "17.39%" }, { "cls_id": "homologset.oma.830443", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P41498-1", "uniprot_id": "PPAC_RAT", "id": "P41498-1", "name": "Low molecular weight phosphotyrosine protein phosphatase", "aln": "MAEVGSKSVLFVCLGNICRSPIAEAVFRKLVTDENVSDNWRIDSAATSTYEVGNPPDYRGQNCMKKHGIHMQHIARQITREDFATFDYILCMDESNLRDLNRKSNQVKNCKAKIELLGSYDPQKQLIIEDPYYGNDSDFEVVYQQCLRCCKAFLEKTH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8C2LH05-1", "uniprot_id": "A0A8C2LH05_CRIGR", "id": "A0A8C2LH05-1", "name": "Low molecular weight phosphotyrosine protein phosphatase", "aln": "MAEAGSNSVLFVCLGNICRSPIAEAVFRKLVTDENVSDNWRIDSAATSTYEVGNPPDYRGQNCMRKHGIPMSHIARQITREDFVTFDYILCMDESNLRDLNRKSNQVKNCKAKIELLGSYDPQKQLIIEDPYYGNDSDFEVVYQQCLRCCKAFLEKTR", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "P24666-1", "uniprot_id": "PPAC_HUMAN", "id": "P24666-1", "name": "Low molecular weight phosphotyrosine protein phosphatase", "aln": "MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P81693-1", "uniprot_id": "PPAC_PIG", "id": "P81693-1", "name": "Low molecular weight phosphotyrosine protein phosphatase", "aln": "MAEQVTKSVLFVCLGNICRSPIAEAVFRKLVTDQNVSDNWVIDSSAVSDWNVGRSPDPRAVSCLRHHGINTAHKARQITKEDFATFDYILCMDESNLRDLNRKGNQVKNCRAKIELLGSYDPQKQLIIEDPYYGNDSDFEAVYQQCVRCCRAFLEKVR", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "P11064-1", "uniprot_id": "PPAC_BOVIN", "id": "P11064-1", "name": "Low molecular weight phosphotyrosine protein phosphatase", "aln": "MAEQVTKSVLFVCLGNICRSPIAEAVFRKLVTDQNISDNWVIDSGAVSDWNVGRSPDPRAVSCLRNHGINTAHKARQVTKEDFVTFDYILCMDESNLRDLNRKSNQVKNCRAKIELLGSYDPQKQLIIEDPYYGNDADFETVYQQCVRCCRAFLEKVR", "tax_id": 9913, "tax_name": "Bovine" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ::**************************:*:*:** :**.*.* :::*..** *. .*::.*** * ***:*:***.*******************.****.*:*************************:***.*****:***:*****.:", "identical_positions": 118, "similar_positions": 30, "identity": "74.68%" }, { "cls_id": "homologset.oma.830868", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYR7-1", "uniprot_id": "ACOT3_MOUSE", "id": "Q9QYR7-1", "name": "Acyl-coenzyme A thioesterase 3", "aln": "-----MHAFTTQNPNRMAPT-------VILEPAGGCLCDQPVHIAVRGLAPEQPVTLRSVLRDEKGALFRAHARYRADSHGELDLARTPALGGSFSGLEPMGLLWAMEPDRPFWRLIKRDVQTPFVVELEVLDGHEPDGGQRLARAVHERHFMAPGVRRVPVREGRVRATLFLPPGTGPFPGIIDLFGIGSGLLEYRASLLAGKGFAVMALAYNNYEDLPKDMDIIHLEYFEEAVTYLLSHPQVTGSGVGVLGISKGGELGFAMASFLKNITAAVIINGSISNIGGNLQYKDETVPSVGINTKRVKRTKDGLKDIVDLLNNPLEGPDQKSLIPVERSDTAFLFLVGQDDHNWKSEFYAREASKRLQAHGKEKPQIICYPETGHHIEPPYFPLCKASLNSLVGGPVIWGGEPRAHAMAQVDAWQQLQTFFHNHLDGKKKTIPAKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A6H9-1", "uniprot_id": "A0A8I6A6H9_RAT", "id": "A0A8I6A6H9-1", "name": "", "aln": "-----MHAFTTQN--RMAPT-------VILEPAVGCLCDQPVHITVRGLGPEQPVTLRAALRDEKGALFRAHARYRADAHGVLDLERAPALGGSFTGLEPMGLIWAMEPERPFWRLVKRDVQTPFVVELEVLDGHEPDGGRLLAQAVHERHFMAPGVRRVPVREGRVRATLFLPP---------DLFGLGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKDVDIIHLEYFEEAVNYLLSHPQVKGSGVGVLGISKGGELGFAMATFLKNITAAVIINGSVANVGGTLQYRDETILPVGMSTKRIKRIKDGLKDIVDALNNPLEGADQKSLIPVERSDTTFLFLVGQDDHNWKSEFYAREASKRLQAHGKEKPQIICYPETGHYIEPPYFPLCKASLHSLVGGPVIWGGEPRAHAMAQVDAWQQLQTFFHKHLGGEKKTIPAKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86TX2-1", "uniprot_id": "ACOT1_HUMAN", "id": "Q86TX2-1", "name": "Acyl-coenzyme A thioesterase 1", "aln": "----------------MAAT-------LILEPAGRCCWDEPVRIAVRGLAPEQPVTLRASLRDEKGALFQAHARYRADTLGELDLERAPALGGSFAGLEPMGLLWALEPEKPLVRLVKRDVRTPLAVELEVLDGHDPDPGRLLCRVRHERYFLPPGVRREPVRAGRVRGTLFLPPEPGPFPGIVDMFGTGGGLLEYRASLLAGKGFAVMALAYYNYEDLPKTMETLHLEYFEEAVNYLLSHPEVKGPGVGLLGISKGGELCLSMASFLKGITAAVVINGSVANVGGTLRYKGETLPPVGVNRNRIKVTKDGYADIVDVLNSPLEGPDQKSFIPVERAESTFLFLVGQDDHNWKSEFYANEACKRLQAHGRRKPQIICYPETGHYIEPPYFPLCRASLHALVGSPIIWGGEPRAHAMAQVDAWKQLQTFFHKHLGGHEGTIPSKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SPG8-1", "uniprot_id": "Q5SPG8_DANRE", "id": "Q5SPG8-1", "name": "", "aln": "MFAVLKHAFSPLARNTLAKMHYSSGVSIRLLPSYKCSFEDPVHVTVSGLNPHQRVDLRSKITDENGLDFKASATYQADDSGQIDLKRDSSLGGSFTGVEPMGLYWALKADTISCKFTLSDVTRPALVDIEVVS-----DDKVLAKVTNERHCLTDGVRRSPVTEGRIRGTLFMPPGKGPFPGILDTNVFRGAPFELRAALLAKRGFAVLALAFQGYQDLPKRADRFHLEYFEEGIDFLRQQPEVKGQKIGLVSISKSGDLALSMATFLPDIAATIWVNGCNANTLVPVYYKDICVPPLLFDVKRTKITPLGLVDIGEVMDDPMSKEGLPSVIPIERAPGSFMFVVSEADRNWRSAYYAKLACDRLKAHGKNNYQLVKYEKAGHFIEVPYMPFCLANFHGVAGQPVFFGGEPKAHAEAQLDAWPKMINFFKKHLAATDHNPRSML", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : * *: * ::**:::* ** *.* * **: : **:* *:* * *:** * :** * .:*****:*:***** **::.: :: ** * *::**:. .: *.:. :**: :. **** ** **:*.***:** * .. :* **:*** :****:***: .*:**** : :*******.: :* .:*:*.* :*::.***.*:* ::**:** .*:*:: :**. :* : *:. : .: .. :* * * ** : ::.*:. . *.**:**: :*:*:*.: *:**:* :**. *..**:***:.: *:: * ::**.** **:*:* *.::.:.* *:::****:*** **:*** :: .**::** . . . : :", "identical_positions": 164, "similar_positions": 137, "identity": "36.94%" }, { "cls_id": "homologset.oma.830869", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q63276-1", "uniprot_id": "BAAT_RAT", "id": "Q63276-1", "name": "Bile acid-CoA:amino acid N-acyltransferase", "aln": "MAKLTAVPLSALVDEPVHIRVTGLTPFQVVCLQASLKDDKGNLFNSQAFYRASEVGEVDLERDSSLGGDYMGVHPMGLFWSMKPEKLLTRLVKRDVMNRPHKVHIKLCHPYFPVEGKVISSSLDSLILERWYVAPGVTRIHVKEGRIRGALFLPPGEGPFPGVIDLFGGAGGLFEFRASLLASHGFATLALAYWGYDDLPSRLEKVDLEYFEEGVEFLLRHPKVLGPGVGILSVCIGAEIGLSMAINLKQITATVLINGPNFVSSNPHVYRGKVFQPTPCSEEFVTTNALGLVEFYRTFEETADKDSKYCF-PIEKAHGHFLFVVGEDDKNLNSKVHAKQAIAQLMKSGKKNWTLLSYPGAGHLIEPPYSPLCSASRMPFVIPSINWGGEVIPHAAAQEHSWKEIQKFLKQHLNPGFNSQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91X34-1", "uniprot_id": "BAAT_MOUSE", "id": "Q91X34-1", "name": "Bile acid-CoA:amino acid N-acyltransferase", "aln": "MAKLTAVPLSALVDEPVHIQVTGLAPFQVVCLQASLKDEKGNLFSSQAFYRASEVGEVDLEHDPSLGGDYMGVHPMGLFWSLKPEKLLGRLIKRDVMNSPYQIHIKACHPYFPLQDIVVSPPLDSLTLERWYVAPGVKRIQVKESRIRGALFLPPGEGPFPGVIDLFGGAGGLMEFRASLLASRGFATLALAYWNYDDLPSRLEKVDLEYFEEGVEFLLRHPKVLGPGVGILSVCIGAEIGLSMAINLKQIRATVLINGPNFVSQSPHVYHGQVYPPVPSNEEFVVTNALGLVEFYRTFQETADKDSKYCF-PIEKAHGHFLFVVGEDDKNLNSKVHANQAIAQLMKNGKKNWTLLSYPGAGHLIEPPYTPLCQASRMPILIPSLSWGGEVIPHAAAQEHSWKEIQKFLKQHLLPDLSSQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14032-1", "uniprot_id": "BAAT_HUMAN", "id": "Q14032-1", "name": "Bile acid-CoA:amino acid N-acyltransferase", "aln": "MIQLTATPVSALVDEPVHIRATGLIPFQMVSFQASLEDENGDMFYSQAHYRANEFGEVDLNHASSLGGDYMGVHPMGLFWSLKPEKLLTRLLKRDVMNRPFQVQVKLYDLELIVNNKVASAPKASLTLERWYVAPGVTRIKVREGRLRGALFLPPGEGLFPGVIDLFGGLGGLLEFRASLLASRGFASLALAYHNYEDLPRKPEVTDLEYFEEAANFLLRHPKVFGSGVGVVSVCQGVQIGLSMAIYLKQVTATVLINGTNFPFGIPQVYHGQIHQPLPHSAQLISTNALGLLELYRTFETTQVGASQYLF-PIEEAQGQFLFIVGEGDKTINSKAHAEQAIGQLKRHGKNNWTLLSYPGAGHLIEPPYSPLCCASTTHDLR--LHWGGEVIPHAAAQEHAWKEIQRFLRKHLIPDVTSQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A287ALR5-1", "uniprot_id": "A0A287ALR5_PIG", "id": "A0A287ALR5-1", "name": "", "aln": "MIQLTATPLSALDDEPMHIRFTGLTPFQIVFLQASLEDERRNMFHSYVYYKANEVGEVNLKQAASLGGDYVGVQPMGLFWSLKSEKVGIKLFKRDVMNSPFQVQLKLCDPAVLLTHIVSTPPIVCLTLERWYVAPGVTRTQGKEGHIRGVLFIPPREGHFPGVIDLFGILSGLMESWASLLASRGSAALALAYCNYEDLPPKLEKLDLEYFEEAVNFLLRHPKILGPGIGIVSISRGAEIGLSMAIHLKQVTATVLINGPNFIIDVPHVYHDQISQTLGFSPQYSSISNLGFIKLQNIFEENKNNANKAAFLPIEKAQG-FPFIVGEEDKNVNSKAHAQQATERLKRHGKKNWTLQSYPGAGHLIEPPHSPLCCGSNVPSFHIAMYWRGEVIPHGATQEHSWKEIQKFLRKHLIPVVTSRF", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A8V0ZD17-1", "uniprot_id": "A0A8V0ZD17_CHICK", "id": "A0A8V0ZD17-1", "name": "", "aln": "MVEVTVTPSSSLADQMVQVVVSGLAPSQLVTLRAWLMDEHGERFQARAFYRSDEEGTVDAGRHAALGGNYTGVWPMGLFWFLQPDSLFKRLVKRDVMGSPFLFHLEVFDGICLLSGQQDN-PLATCTAERWYVGPGVQRVPIREGRVRGALLLPPGPGPFPAVIDLFGGAGGLIEFRAGLLASRGFAVLALAFFAYEDLPKGLTQLDLDYFEEAVELLLRHPKVRGPGLGVIGVSKGAEVALAMAAFLPQVVATVWINGTTFLYGNPLHYKGLRIPSIPYQTERMLFTELGAMDNSAIFADPRSPAYSSSAIPVEKIQGKVLFVVGEADRSFNSKLFAQLATERLP---QDAYRLLSYPGAGHLIEPPGSPLCSISSLRGSPRPVVWGGEPVPHARAQQHSWQEIVQFLELHLNPVPAIKL", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::*..* *:* *: ::: :** * *:* ::* * *:. : * : ..*::.* * *: : .:***:* ** ****** ::.:.: :*.*****. *. .::: . : . . *****.*** * :*.::**.*::** * **.****** .**:* *.****:* * ****: *:*** **:****..::******: *.*:*::.:. *.::.*:** * *: *** ***..* * *:. . . : . ** :. * . *:*: :* . *:*** *:..*** .*: * :* :. : * ************ :*** * : * ** :**. :*:*:*:** :**. ** * ::", "identical_positions": 159, "similar_positions": 116, "identity": "37.77%" }, { "cls_id": "homologset.oma.830870", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q32Q92-1", "uniprot_id": "ACOT6_MOUSE", "id": "Q32Q92-1", "name": "Acyl-coenzyme A thioesterase 6", "aln": "MAATLSVEPAGRSCWDEPLSIAVRGLAPEQPVTLRSVLRDEKGMLFRAHARYRADSHGELDLARTPALGGSFSGLEPMGLLWAMEPDRPFWRLIKRDVQIPFVVELEVLDGHEPDGGQRLARAVHERHFMAPGVRRVPVREGRVRATLFLPPGKGQFPGIIDLYGSIGGLCEHRASLLAGHGFAVLALAYFQFEDLPENLSDVRLEYFEEALALMLRHPQVKGPNIGLIGVSKGADLCLSMAAFLKDNITATVLINACVANTLVPLYYKDLFVPELGCDQTK---NKSGLMDLRDMWNNPLEEPNHQSLIPLEKAQGPFLFLVGMDDHNWKSDVYARIACERLQAHGKDRPQIIYYPETGHCIEPPYFPPPIATVHFVLGEAVFNGGKPRAQSRAQLDAWQRIQTFFQKYLNGEKPARHSKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3I5F7-1", "uniprot_id": "ACOT6_HUMAN", "id": "Q3I5F7-1", "name": "Acyl-coenzyme A thioesterase 6", "aln": "MAATLILEPAGRCCWDEPLRIAVRGLAPEQPVTLRTSLRDEEGALFRAHARYRADARDELDLERAPALGGSFAGLQPMGLLWALEPEKALVRLVKRDVRTPFAVELEVLDGHDTEPGRLLCLAQNKRDFLRPGVRREPVRAGPVRAALFLPPDEGPFPGIIDLFGSSRGLCEYRASLLAGHGFAVLALAYFRFEDLPEDLNDVHLEYFEEAVDFMLQHPKVKGPSIALLGFSKGGDLCLSMASFLKG-ITATVLINACVANTVAPLHYKDMIIPKLVDDLGKVKITKSGFLTFMDTWSNPLEEHNHQSLVPLEKAQVPFLFIVGMDDQSWKSEFYAQIASERLQAHGKERPQIICYPETGHCIDPPYFPPSRASVHAVLGEAIFYGGEPKAHSKAQVDAWQQIQTFFHKHLNGKKSVKHSKI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** :*****.****** ***************: ****:* ***********::.**** *:*******:**:*******:**::.: **:****: **.*********:.: *: *. * ::*.*: ***** *** * ***:*****.:* *******:** ****:******************:******:*.**:*******: :**:**:****.*.*:*.***.*******:***. **************:.**:***:::*:* * * .***:: : * *.***** *****:****** ****:*****:.***:.**:**.********:***** ********:******. *:** *****:* **:*:*:*:**:****:*****:*:***:*..:***:", "identical_positions": 301, "similar_positions": 85, "identity": "71.33%" }, { "cls_id": "homologset.oma.830872", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N9L9-1", "uniprot_id": "ACOT4_HUMAN", "id": "Q8N9L9-1", "name": "Peroxisomal succinyl-coenzyme A thioesterase", "aln": "----------------------------------------------------------------------MSATLILEPPGRCCWNEPVRIAVRGLAPEQRVTLRASLRDEKGALFRAHARYCADARGELDLERAPALGGSFAGLEPMGLLWALEPEKPFWRFLKRDVQIPFVVELEVLDGHDPEP--GRLLCQAQHERHFLPPGVRRQSVRAGRVRATLFLPPGPGPFPGIIDIFGIGGGLLEYRASLLAGHGFATLALAYYNFEDLPNNMDNISLEYFEEAVCYMLQHPQVKGPGIGLLGISLGADICLSMASFLKNVSATVSINGSGISGNTAINYKHSSIPPLGYDLRRIKVAFSGLVDIVDIRNALVGGYKNPSMIPIEKAQGPILLIVGQDDHNWRSELYAQTVSERLQAHGKEKPQIICYPGTGHYIEPPYFPLCPASLHRLLNKHVIWGGEPRAHSKAQEDAWKQILAFFCKHLGGTQKTAVPKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1S3I9-1", "uniprot_id": "F1S3I9_PIG", "id": "F1S3I9-1", "name": "Acyl-coenzyme A thioesterase 4", "aln": "----------------------------------------------------------------------MAATVVLEPAGRCRWDEPVRIAVRGLAPGQRVTLRASLRDEKGALFRAHARYCADADGQLDLARAPALGGSFVGLEPMGLLWALEPEKPFWRFVKRDVQTPFAVKLEVFDGHEPEPQAEQLLSVAVHERDFLPPGVRREPVRAGRVRATLFLPPGLGPFPGIIDIFGMGGGLLEYRASLLAGHGFATLALAYCDFEDLPKKFDTIHLDYFEEALCYMLQHTQVKGPGIGLLGISLGADICLSMASFLKNISATVSINGSGFNGNKPIYYKETSIPPLGHDLRRMKVAFSGLLDIVDIRNDIVGGYENPCMIPIEKAQGPILFIVGQDDHNWRSELYAQIASERLQAHGKGKAQIISYPGTGHYIEPPYFPMCPASLHRLLDKPVIWGGEPRAHSKAQIDAWKQILTFFSKHLG-----ASPKL", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "D3ZIQ1-1", "uniprot_id": "D3ZIQ1_RAT", "id": "D3ZIQ1-1", "name": "", "aln": "MGVERSRILWPESRIKAQPRSQTSDLSVPKLLTDFGASLVWVLETHQVGSTAGQALLRTPRGALVSFQLPMAATLSLEPAGRSCWDEPLSITVRGLAPEQPVTLRAALRDEKGALFRAHARYHADSHGMLDLARAPALGGSFAGLEPMGLLWAMEPERPFWRLIKRDVQTPFVVELEVLDGHEPDG--GQRLARAVHERHFMAPGVRRVPVREGRVRATLFLPPGQGPFPGIIDVYGVGGGLLEYRASLLAGHGFATLALAFYGFEDLPKEFNVIEVDYFEEAVCYMLQHPKVKGPDIGLLGLSLGADVCLIMASFLKNVSATVSINGSAFSGNRYIHYKQTMIPPLGHDLRRTKVAFSGILDIVDIRNDAVGGCENPSMIPIEKAKGPILFVAGQDDHCWRSELYTQIASERLQAHGKERPQIISYPGTGHYIEPPYFPMCPASLHKIVNKAVVWGGEVRAHSKAQIDAWKQILSFFGKHLDSTHNRASCRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2KID4-1", "uniprot_id": "DNAL1_BOVIN", "id": "Q2KID4-1", "name": "Dynein axonemal light chain 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------MAKATTIKEALARWEEK---------------------------------------------------------TSQKPSEAREIKLYAQIPP-----------------IEKMDASLSTLSNCEKLSLSTNCIEKIAN------LNGLKNLRILSLGRNNIKN-LNGLEAVGDTLEELWISYNFIEKLKG-------------IHVMKKLKILYMSNNLVKDWAEFVKLAELPCLEDLVFVGN------PLEEKHS--------AEGNWVEEATKRVP----------------------------------KLKKLDGTPVIKEDEEEDN------------------------------", "tax_id": 9913, "tax_name": "Bovine" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*.:: ::. * . : . . .:: :** : : *** : . .*:*: :*.:.: :: ::: * : ::*. ** .:. : .*::::.. *. * :. :* : . * : :: :.: . * *:*: :. : * .* : .*::: .. *: .* . : ", "identical_positions": 27, "similar_positions": 78, "identity": "5.48%" }, { "cls_id": "homologset.oma.830873", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A287B8D4-1", "uniprot_id": "A0A287B8D4_PIG", "id": "A0A287B8D4-1", "name": "Bile acid-CoA:amino acid N-acyltransferase", "aln": "-MFQLTATPASALADEPVHIRVMGLAPLQVVTLMASLKDEKGNLFQSRAFYRANEAGELDLEQDPALGGDFVGVHPMGLFWSLKPEKPFGGLLKLEVMNSPFWITLDLYDSVYLQKSGVVQPRASLELQRWFSSPGVQRLMIREGRVRGALFLPPGEGPFPGIIDLFGGIGGLLEYRAGLLAAHGFAALALAYFAYDDLPNQLQEVDLDYFEEAANLLLAHPKIQKPGIGVISVSKGAEIGLAMACYLKQVVATVCINGSNAIFEVPLRYRDLVLTPIPSFLERMEVNASGAVRLRHCMGDPRDELNQQSVLPIEKSQGQILFIIGEDDECLNSRDYAEQALGQLQSHGRSNGRMLLYPGAGHLIEPPYGPLCYGSRTRGFPLPLLWGGDPVAHAAAQEHAWREILKFFRQHLVGSRSKL", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0AAA9SQX8-1", "uniprot_id": "A0AAA9SQX8_BOVIN", "id": "A0AAA9SQX8-1", "name": "Bile acid-CoA:amino acid N-acyltransferase", "aln": "-MFQLTVTPASALADEPVHIQATGLPPLQMVTLIATMKDDKGNLYRSRAFYRANEAGELDLKRDPAVGGHYMGVHPMGLLWSLKPERPFDRLIKRNVMNTPTWITLDLYDSVYIHKVGEAQPKASQVLQRWFSSPDLQRVPIREGRIRGALFLPPGEGPFPGLLDLFGGIGGLVEYRASLLAVRGFAVLALAYFAYDDLPKQLEEVDLEYFEEAANLLLAHPKVQKPGIGVISVSKGAEIGLAMACYLKQVAATVCINGANAIHEFPLRYRDLVITPIPSFPERMQVNAAGAVRIRHFKGDPRDERNQHSVLPVEKARGPILFVVGEADECFNSKEYAEQALDQLRRHGKSSGRMLSYPGAGHLIEPPYAPLCCVSWSRGLFLPMLWGGEPEGQAAAQEHSWQEILKFFRQHLVLSRSTL", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A2AKK5-1", "uniprot_id": "ACNT1_MOUSE", "id": "A2AKK5-1", "name": "Acyl-coenzyme A amino acid N-acyltransferase 1", "aln": "MMIKLIATPSNALVDEPVSIRATGLPPSQIVTIKATVKDENDNVFQSQAFYKTNEAGEVDLEKTPALGGDYVGVHPMGLFFSLKPKKAFHRLMKKDVMNSPFCICLDLYDSVNWLETVRIPSKASQRVQRWFVGPGVKREQIQEGRVRGALFLPPGKGPFPGIIDLFGVIGGLVEFRASLLASHGFAVLALAYFAYKDLPEKLQEVDLEYFEEAANFLLSHPKIQQPGIGVISTSKGAEIGLAMACYLKQVIATVCINGATTTTAVPLRYQDLVVTPIQQALERMEVHVSGAVCFRHTT----QYLQNKNILPVEKAQGKILFIVGENDELLDSKLHAQRAMDRLRRHGRSSGRMLAYPGAGHLIEPPYSPLCFASWQPVLGRPMCFGGDLMAHAAAQEHSWREIQKFFRKHLLQSGSKL", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::* .**:.**.**** *:. **.* *:**: *::**::.*:::*:***::*****:**:: **:**.::*******::****::.* *:* :***:* * ******* : .:** :**** .*.::* *:***:*********:*****::**** ****:*:**.*** :***.********.***::*:****:*******:**:***:*:*******.***************** *******:.: .****:***:*** . ***:*:.:*** :** : :::.:**:**::* ***::** ** ::*: :*::*:.:*: **:*.**** ************.*** * : *: :**: .:******:*:** ****:**: * *.*", "identical_positions": 244, "similar_positions": 112, "identity": "58.1%" }, { "cls_id": "homologset.oma.830876", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGG9-1", "uniprot_id": "ACNT2_MOUSE", "id": "Q8BGG9-1", "name": "Acyl-coenzyme A amino acid N-acyltransferase 2", "aln": "MMIQLIATPSNALVDEPVSIRATGLPPSQIVTIKATVKDENDNVFQSQAFYKTNEAGEVDLEKTPALGGDYVGVHPMGLFFSLKPKKAFHRLMKKDVMNSPLCICLDLYDSVNWLETVRIPSKASQRVQRWFVGPGVKREQIQEGRVRGALFLPPGKGPFPGIIDLFGLIGGLVEFRASLLASHGFAVLALAYFAYEDLPEKPQEVDLEYFEEAANFLLSHPKIQQPGIGVISTSKGAEIGLAMACYLKQVIATVCINGPTTITIFPLRYQDLVMTPIHPALERIQVHDSGALLFRYTTQYLHNKLNSQNILPVEKAQGKILFIVGENDECLDSKLHAQKAMDRLQRHGRSSGRMLAYPGAGHLIEPPYSPVCFVAWFPVLGQPMCFGGDLMAHAAAQEHSWREIQKFFRKHLLQSGSKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5FVR5-1", "uniprot_id": "ACNT2_RAT", "id": "Q5FVR5-1", "name": "Acyl-coenzyme A amino acid N-acyltransferase 2", "aln": "-MLQLIATPSNALADEPVSIRAIGLPPSQIVTITATVKDEKENLFQSKAFYKANEAGEVDLEQASALGGDYVGVHPMGLFCCLKPKRAFQRLIKKDVMNSPLCICLDLYDSVCWLETVRIPPKASQIVHRWFAGPGVKREQIREGRVRGALFLPPGKGPFPGIIDLFGSIGGLVEFRASLLASRGFAVLALAYFAYEDLPKVLLEEDLDYFEEAANFLLAHPKIQQPGIGVISVSKGAEIGLAMACYLKQVVATVCINGPSAIFDFPLKYRDLVVTPMRLAFEKIQFHGSGAACFRHCWD-PQNMLNPPKILPVEKAQGKILFIVGENDQCLASKLHAQRAMDRLRSHGRSSGRMLAYPGAGHLIEPPYSPFCFACWDSVLGKPMLWGGDPIAHAAAQVHSWREIQKFFRQHLLQSGGKL", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:**********.******** **********.******::*:***:****:*********::.*************** .****:**:**:******************* ********.**** *:***.*********:************************* **************:****************: * **:**********:*************.*****************:********::* ***:*:***:**:: *:*:**.*.*** **: : :* **. :*******************:** ******:*****: ************************.**..* .***:** :*** :****** ***********:******.**", "identical_positions": 340, "similar_positions": 53, "identity": "80.95%" }, { "cls_id": "homologset.oma.830881", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BWN8-1", "uniprot_id": "ACOT4_MOUSE", "id": "Q8BWN8-1", "name": "Peroxisomal succinyl-coenzyme A thioesterase", "aln": "MAATLSVEPTGRSCWDEPLSIAVRGLAPEQPVTLRSVLRDEKGALFRAHARYRADSHGELDLARVPALGGSFSGLEPMGLLWAMEPDRPFWRLIKRDVQTPFLVELEVLDGHEPDGGRRLARTVHERHFMAPGVRRVPVREGRVRATLFLPPGQGPFPGIIDVYGVGGGLLEYRAGLVAGHGFATLALAFYDFEDLPKELNVIEVDYFEEAVRYMLRHPKVKGPDIGLLGLSLGADVCLIMASFLNNVSATVSINGSAFSGNRHIKYKQTMIPPLGHDLRRMKVAFSGILDIVDIRNDAVGGCENPSMIPIEKAKGPILFVAGQDDHCWRSELYTQIASDRLQAHGKERPQVLSYPGTGHYIEPPYFPMCPASLHKIVNEAVIWGGEVKAHSKAQIDAWKQILFFFGKHLGSTHSRASCRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E1BBG0-1", "uniprot_id": "E1BBG0_BOVIN", "id": "E1BBG0-1", "name": "", "aln": "MVATVTLEPAGRCRWDEPVRITVRGLAPGQPVTLRASLRDEKGALFRAHARYCADATGLLDLERALALGGSFAGLEPMGLFWALEPEKPFWRFLKRDVQTPFAVELEVLDGHEPETQRLLGRAVHERDFLAPGVRREPVRAGRVRATLFLPPGSGPFPGIIDIYGIGGGLLEYRASLLAGHGFATLAVAYYSFEDLPKKFDTIDLDYFEEALCYMLQHAQIKGPGIGLLGISLGADICLSMASFLKNVSATVTINGSGFNGNKAMYYKENCIPPLGHDLRRVKVAFSGLVDIVDVRNDIVGGCENPCMIPIEKAQGPILFIVGQDDHNWRSEFCAQIASERLQAHGKEKPQIISYPGTGHYIEPPYFPMCPASLHKLLDKPVMWGGEPRAHSKAQVDAWKKILTFFTKHLG-----LSPKL", "tax_id": 9913, "tax_name": "Bovine" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.**:::**:**. ****: *:****** ******: *************** **: * *** *. ******:*******:**:**::****::******** ***********: * *.*:****.*:****** *** ************.********:**:*********.*:*********:*:*.******:::.*::******: ***:*.::***.*****:*****:** *****:******:****.*.**: : **:. **********:******::****:*** *******.*******:*****:.***** ****: :****:********:**::***********************::::.*:**** :******:****:** ** **** * :*", "identical_positions": 311, "similar_positions": 77, "identity": "73.87%" }, { "cls_id": "homologset.oma.830887", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O88267-1", "uniprot_id": "ACOT1_RAT", "id": "O88267-1", "name": "Acyl-coenzyme A thioesterase 1", "aln": "MEATLSLEPAGRSCWDEPLSITVRGLVPEQPVTLRAALRDEKGALFRARALYRADAHGELDLARAPALGGSFTGLEPMGLIWAMEPERPFWRLVKRDVQTPFVVELEVLDGHEPDGGRLLARAVHERHFMAPGVRRVPVREGRVRATLFLPPEPGPFPGIIDLFGVGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKTMETMRIEYFEEAVNYLRGHPEVKGPGIGLLGISKGGELGLAMASFLKGITAAVVINGSVAAVGNTICYKDETIPPVTILRNQVKMTKDGLKDVVDALQSPLVEQKSFIPVERSDTTFLFLVGQDDHNWKSEFYANEISKRLQAHGKEKPQIICYPEAGHYIEPPYFPLCSAGMHLLVGANITFGGEPKPHSVAQLDAWQQLQTFFHKQLGGKSHGVSPKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55137-1", "uniprot_id": "ACOT1_MOUSE", "id": "O55137-1", "name": "Acyl-coenzyme A thioesterase 1", "aln": "MEATLNLEPSGRSCWDEPLSIAVRGLAPEQPVTLRSVLRDEKGALFRAHARYRADSHGELDLARTPALGGSFSGLEPMGLLWAMEPDRPFWRLVKRDVQTPFVVELEVLDGHEPDGGQRLAHAVHERHFLAPGVRRVPVREGRVRATLFLPPEPGPFPGIIDLFGVGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKNMETMHMEYFEEAVNYLRSHPEVKGPGIGLLGISKGGELGLAMASFLKGITAAVVINGSVAAVGNTISYKDETIPPVTILRNQVKMTKDGLKDVVDALQSPLVDKKSFIPVERSDTTFLFLVGQDDHNWKSEFYADEISKRLQAHGKEKPQIICYPAAGHYIEPPYFPLCSAGMHLLVGANITFGGEPKPHAMAQLDAWQQLQTFFHKQLGSECLHVSPKI", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****.***:***********:****.********:.***********:* ****:********:*******:*******:*****:******************************: **:*******:********************************************************************.****::***********.************************************************.***********************************::******************************:******************** **********************************::******************.:. *****", "identical_positions": 386, "similar_positions": 28, "identity": "92.12%" }, { "cls_id": "homologset.oma.830899", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O55171-1", "uniprot_id": "ACOT2_RAT", "id": "O55171-1", "name": "Acyl-coenzyme A thioesterase 2, mitochondrial", "aln": "MVASSFAVLRASRLCQWGWKSWTQLSGPPPLSTGGRTTFARTNATLSLEPGSRSCWDEPLSITVRGLAPEQPVTLRAALRDEKGALFRAHARYRADAGGELDLARAPALGGSFTGLEPMGLIWAMEPERPLWRLVKRDVQKPYVVELEVLDGHEPDGGQRLAQAVHERHFMAPGVRRVPVRDGRVRATLFLPPEPGPFPEIIDLFGVGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKTMETMRIEYFEEAVNYLRGHPEVKGPGIGLLGISKGGELGLAMASFLKGITAAVVINGSVAAVGNTVCYKDETIPPVSLLRDKVKMTKDGLLDVVEALQSPLVDKKSFIPVERSDTTFLFLVGQDDHNWKSEFYAREASKRLQAHGKEKPQIICYPEAGHYIEPPYFPLCSAGMHLLVGANITFGGEPKPHSVAQLDAWQQLQTFFHKQLSGKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYR9-1", "uniprot_id": "ACOT2_MOUSE", "id": "Q9QYR9-1", "name": "Acyl-coenzyme A thioesterase 2, mitochondrial", "aln": "MVASSFAVLRASRLCQQDWKSWARLFVPPPLSTGGRTTWARTNATLSVEPEGRSCWDEPLSIAVRGLAPEQPVTLRSALRDEKGALFRAHARYRADAGGELNLARAPALGGSFSGLEPMGLLWAMEPERPLWRLIKRDVQTPFLVELEVLDGHEPDGGQRLAQAVHERHFLAPGVRRVPVREGRVRATLFLPPEPGPFPGIIDLFGVGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKSIETMHMEYFEEAVNYLRSHPEVKGPGIGLLGISKGGELGLAMASFLKGITAAVVINGSVAAVGNTISYKDETIPPVSLLRNQVKMTKDGLLDVVEALQSPLVDKKSFIPVERSDTTFLFLVGQDDHNWKSEFYADEISKRLQAHGKEKPQIICYPAAGHYIEPPYFPLCSAGMHLLVGANITFGGEPRAHAVAQVDAWQQLQTFFHKQLGSKS", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************** .****::* ***********:********:** .**********:*************:************************:***********:*******:************:*****.*::**************************:**********:***************** ***************************************::***::***********.***********************************************:.*************::**************************************************** * ****************** *******************************:.*:***:**************..**", "identical_positions": 413, "similar_positions": 32, "identity": "91.17%" }, { "cls_id": "homologset.oma.830931", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZF13-1", "uniprot_id": "D3ZF13_RAT", "id": "D3ZF13-1", "name": "Acyl carrier protein", "aln": "MASRVLCACVRRLPAAFAPLPRLPTLALARPLSTILCPEGIWRRTGTLQPTLALAQVPGTVTHLCRQYSDAPPLTLEGIRDRVLYVLKLYDKIDPEKLSVNSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CR21-1", "uniprot_id": "ACPM_MOUSE", "id": "Q9CR21-1", "name": "Acyl carrier protein, mitochondrial", "aln": "MASRVLCACVRRLPAAFAPLPRLPTLALARPLSTTLCPEGIRRRPGALQSALALAQVPGTVTHLCRQYSDAPPLTLDGIKDRVLYVLKLYDKIDPEKLSVNSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3X6L0-1", "uniprot_id": "G3X6L0_BOVIN", "id": "G3X6L0-1", "name": "Acyl carrier protein", "aln": "MAARVLCACVRRLPTAFAPLPRLPTLAAARPLSTTLFAAETRTRPGAPLPALVLAQVPGRVTQLCRQYSDAPPLTLEGIKDRVLYVLKLYDKIDPEKLSVNSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYE", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A287AAR5-1", "uniprot_id": "A0A287AAR5_PIG", "id": "A0A287AAR5-1", "name": "Acyl carrier protein", "aln": "MAARVLCACVRRLPAAFAPLPRIPTVVAARPLSTTLFPTGAQARSRALQPALVLAQAPGGVTQLCRRYSDAPPLTLEAIKDRVLYVLKLYDKIDPEKLSVNSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYE", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "O14561-1", "uniprot_id": "ACPM_HUMAN", "id": "O14561-1", "name": "Acyl carrier protein, mitochondrial", "aln": "MASRVLSAYVSRLPAAFAPLPRVRMLAVARPLSTALCSAGTQTRLGTLQPALVLAQVPGRVTQLCRQYSDMPPLTLEGIQDRVLYVLKLYDKIDPEKLSVNSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:***.* * ***:*******: :. ****** * . * : .:*.***.** **:***:*** *****:.*:***************************************************************************:", "identical_positions": 120, "similar_positions": 18, "identity": "76.92%" }, { "cls_id": "homologset.oma.831362", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q75WE7-1", "uniprot_id": "VWA5A_RAT", "id": "Q75WE7-1", "name": "von Willebrand factor A domain-containing protein 5A", "aln": "----------------------------------------------------------MEHHWGLITG-NKEKVPLKSISVTLSINDFVAAVAATLHYENEEKVPIEAMFVFPMDEDSAVYSFEALVDGKKIVAELQDKTKAHSKYEEALSQGHQAYLLEEDDYSRDVFSCNVGNLQPGTKVAVTLRYVQELPLESDGALRYLLPAVLNPRYQLSEQSASSCLNVQKPIVPLEALPYTLSMVATITSQHGIERVQSNCSLSPIQYLTDDKTSAQVSLTEGHKFDRDVELLIYYREVHSPSVAVEKGMQDKKRDSLMGAPCAMVSFYPDIP--EVNASKVCGEFVFLMDRSGSMQTPMRTEENSQLRIEAAKETLLLLLKSLPMGCYFNIYGFGSSYEQFFPESVKYTQETIEEAVERVKRLDADLGGTEILTPLRNIYKTSSIPGHPLQLFVFTDGEVSDTYSVIREVKLNSKKHRCFSFGIGQGASTSLIKNIARVSGGTAEFITGKDRMQAKALGSLKLALQCALDDISLSWELPPGLSVNMLSPEQPTIFRGQRLIIYAQLTGPMPQAESRGAVCLKHTLQGKSLENKVAFSLQPKEN-ANFTIHRLAAKFLIQTKDLGSHEVSKEEKKD-VMNISLQSGVLSSFTAFVAINKELNKPVQGPLAHRVIPRPMIATSTSMFMRSCSRLTGPFKNSRLK------------------------RRLCAADYVPYGHESTVYSSMPSPAPIENQGVADSSNEKSNSQNEHKAFGENV--VLQLIFLQNANGSWKLDENLTKILGTTLEDTKAANPSQHGDPSAWATILAVLWLHANGQDLKCEWELLERKAVAWLHDHAGRGTTPPPFPSFHLHPREPCLYVLQRTQESLWLSQLCCLRTLSLQLILHFQD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99KC8-1", "uniprot_id": "VMA5A_MOUSE", "id": "Q99KC8-1", "name": "von Willebrand factor A domain-containing protein 5A", "aln": "----------------------------------------------------------MEHHCGLITS-NKETVPLKNISVTLSINEFVAAVVATLNYENEEKVPLEATFVFPMDEDSAVYSFEALVDGKKIVAELQDKMKAHSEYEEALSQGHQAYLLEEDDYSRDVFSCNVGNLQPGAKVAVTLRYVQELPLETDGALRYLLPAILNPRYQLSEQSANSCLNIQKPTVPLEDLPYTLNMTATITSQHGIERVQSNCSLSPIQYLTDDKTSAQVSLTEGHKFDRDVELLIYYNEVHSPSVAVEMGMLDMKPDSLMGAPSAMVSFYPDIP--EVEASKACGEFVFLMDRSGSMDSPMSTENNSQLRIEAAKETLLLLLKSLPMGCYFNIYGFGSSYEKFFPESVKYTQDTMEDAVKRVKALKANLGGTEILTPLCNIYKASSIPGHPLQLFVFTDGEVSDTFSVIREVKLNSKKHRCFSFGIGQGASTSLIKNIARVSGGTAVFITGKDRMQTKALGSLKFALQCAVDNISLSWDLPPGLSVKMLSPEQLTIFRGQRLIIYAQLTGLMPQVESTGAVCLKHILQGRSLENRVTFSLQPKAN-DNFTIHRLAAKSLIQTKDFGSQEASKEEKED-VMNISLQSGVLSSFTAFIAINKELNKPVQGPLAHRVIPRPVMAGSSS--MRFYSSFSGGFKGP-QP------------------------RSLRVPAYDLCSAESANLVLKKSACSAIQKKKTNSSTNKSNLKKEHKAFGENA--VVQLISLQKANGSWELDEDLTKILGTKSKDIKAANPAKHEDPSAWSTVLAVVWLHANGTDLKCEWELLERKAVAWLHDHAG-------------------------SSIPMLVQAANSLLKLSVNPAVFGV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1N0E6-1", "uniprot_id": "F1N0E6_BOVIN", "id": "F1N0E6-1", "name": "von Willebrand factor A domain-containing protein 5A", "aln": "----------------------------------------------------------MVHPGGLLTP-REKPVPLKSISVTLSICEFVAGVSATLNYKNEEEVPLEAFFIFPMDEDSAVYSFEAMVDGKKIKAELQDKMTAHTNYENAIIRGHQAFLLEEDMCSRDVFCCNVGNLLPGSQAELTLKYVQELPLEADGALRYVLPAILNPRYQLSGCSEDSCLNMKTPVVSLEDLPYTISMVATISSQHGIDRIQSNCSLSPIEYLGDNKTSAQVSLADGHKFDRDVEFLIYYRAVHTPSVVVEMGESPTKSDGVLGDPAAMVTFYPNIP--EAQPSIACGEFIFLMDCSGSMQSPISKQSKSQLRIDVAKETLILLLKSLPLGCYFNIYEFGSTYEAFFPNSVKYAQSTVEEALRRVKLMRANLRGTEILTALQHIYKQPSVPGHPLQVFVFTDGEVTDTFTVVREVKSHRLRHRCFSFGIGEGVSTSLVKGIARASRGTSEFITGKERMQAKALRALKRSLQPVVDDVSLSWDLPDGLSAKMLSPEQTVLFRGQRLILYAQLTGTMPPAEATGEVCLKYTLQGESLENKVAFSLQPKLD-ANLTIHRLAAKSFLQTKDMGLRETAAGDKKD-VLKVSMECGVISSHTAFIAVNKDLNKPIQGPLAPRDVPRPMLMYATPVMQSLSPPRCGTGRRT----------------------------------HLGLGHRKEK-KCTSLSEARLEKPKSRASAKKTNVETHGPVVEDNR--LVELISLQKADGSWDLNEGLALVLGMKLEDIQAALPDKDANSSSWATVLAVLWLHDNAKDMACEWELLERKAVAWIHIHAG-------------------------SVRHELVKAAVAFMKSSADPAIFGP-", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A287BGY6-1", "uniprot_id": "A0A287BGY6_PIG", "id": "A0A287BGY6-1", "name": "von Willebrand factor A domain-containing protein 5A", "aln": "----------------------------------------------------------MVQLCGLLTC-QEEPVPLKSISVTLSICEFVAGVSVTLNYENEEKVPLEVFFVFPMDEDSAVYSFEAMVDGKKIQAELQEKMKAHSNYENAISQGQQAFLLEEDKCSRDVFCCNVGNLPPGSKAALTLKYVQELPLEADGALRYVLPAILNPRYQLSGGPEDSCLKMKAPVVPLEDLPYTISLVATISSQHSIERIQSNCILSPTEYLDDKKTSARVSLADGHKFDRDVELLIYYSDVHTPSVALEMGKPMQKPDSLMGDTAAMVSFYPDIP--EAEP-VTCGEFVFLMDRSGSMQGPMSKQDKSQSRIDAAKETLTLLLKSLPIGCYFNVYGFGSSYEAFFPNSVQYTQQTMEEALRRVKLMRADLGGTEILIPLQFIYRGPSIPGHPLQLFVFTDGEVTDTFSVIREVRSNRERHRCFSFGIGEGASTSLIKGIARVSRGTSEFIIGKERMQAKALRALKRSLQPVVEDVSLSCDLPQGLSAKMLSPEQTVIFRGQRLIVYAQLTGTMPSAEATGEVCLKYTLQGKSFENKVTFSLQPKHD-DNFTIHRLAAKSFLQTKDMGFRETSAGDKKE-VLEVSIESGVISSHTAYIAINKDLNKPVQGPLARRDIPTPFLLSTT----AMTPWKRACRLDR----------------------------------SHALGHRQKK-KGLSLKETSPELERAHSSNKRTNLETHHPVFGENY--LVQLISLQKADGSWDLCEGLAIVLGVKLRDIRDAFTIKNADLTSWATALAVLWLHANGQDLKCEWELLERKAVAWIHNHAG-------------------------SVRHLLVKNAIAFLKSPVDPSVFAL-", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "O00534-1", "uniprot_id": "VMA5A_HUMAN", "id": "O00534-1", "name": "von Willebrand factor A domain-containing protein 5A", "aln": "----------------------------------------------------------MVHFCGLLTL-HREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQELPLEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTLSMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTPSVVLEMGMPNMKPGHLMGDPSAMVSFYPNIP--EDQPSNTCGEFIFLMDRSGSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPVVEDVSLSWHLPPGLSAKMLSPEQTVIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQPKPD-VNLTIHRLAAKSLLQTKDMGLRETPASDKKD-ALNLSLESGVISSFTAFIAINKELNKPVQGPLAHRDVPRPILLGASAPLKIKCQSGFRKALHS----------------------------------DRPPSASQPRGELMCYKAKTFQMDDYSLCGLISHKDQHSPGFGENH--LVQLIYHQNANGSWDLNEDLAKILGMSLEEIMAAQPAELVDSSGWATILAVIWLHSNGKDLKCEWELLERKAVAWMRAHAG-------------------------STMPSVVKAAITFLKSSVDPAIFAF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q54MG1-1", "uniprot_id": "Y5981_DICDI", "id": "Q54MG1-1", "name": "von Willebrand factor A domain-containing protein DDB_G0285981", "aln": "MLQSLKNVFFSETTTTTTTSTTTPVSNSAIKRYIGNINDYKNANYFNYYRILENKYDYLRDTFGLKTFSNNETFKLIDFTIDSEMNNTCITSIWNQKYSNNSSIPVEGIYKIPLAPYSVISGFTVEYQDKVFIGKIKSKEKAQNQYSDSIASGGQAFLAEKTQDGQ--FSFRIGNLPPNENVTIHLTIISGVCPHLS-SLQNCFHRFLFPNYSFN-FQFNLNIKLTLPIKTIELLYYPNREIKFKENSN--------------------NKEATLTFSSKNGIDSDIVCIVE------PENDIERPQSIIEHSKLNNTYAVSVNFTPSFSHLTSDDVNQKSEFIFLIDCSGSMSGEP---------IKKAKRALEIIIRSLNENCKFNIYCFGSRFTKAFDNSKMYNDETLAQISGYVEKIDADLGGTELLPPIRDILSTESDFEYPRQLFILTDGEVSERDSLINYVATESNNTRIFTYGIGNSVDTELVIGLSKACKGYYEMIKDNSNFEEQVMKLVSIAFEPTLSNIKVDWGT--ELQIEQGPTKIRPLYSGETLIVYALLKDNKIPQSTVQVSLIGDGPTGSKLEFPITLDFSKTIDYENNSVHTLAAFNIIKDLEEVERKGNHSNNRDRIEELGKSYGLISKYTSYIVTAASEQVTEETMKTLNIIQTPTTTTTTSHSNRRREEADHTMNQTLLKNCAVVDDLFESCEMLSETSIKFECNRVYKKIPSSLSKIFSFFSSLSTSSSVRSEVVSNFDNDIESEEKKNNSINNNSDSLLKLIKLQKANGSWSSPFSEFKIDLSK-------KPSNIDSDDIWITLIVINKILNDYPTQQSQYDLVIQKASKWVKQQLT----------------------------RLNIPNQYGSLLATSKLHI----", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ** * ..: . * .::: .: : . :*.*:..:*:* : :*: *.: .* . :.* : .:::.* .*:.:*..:: * **:* * .: *. .:*** *. :. : * :. : . . :*: : .* *.*.:. . ::: * .:* * *. ..: :..* :::: : :* *: :: *. :* : . : . .. *.* *.:. : .**:**:* ****. *. **.:* ::::** .* **:* *** : * :* * :.*: : *: : *:* ***:* .: * * :* *:*::*****:: :::. * . . * *::***:...*.*: .:::.. * :* .:..:: :.: :. ::: .:.::.:. *. : ..: :: *: ** ** *.. .: : * .:* ::: :. . : * ::* *** ::: : :: ::.: ::. . *::*..*:::. . : . : : . : * :: . . . . . :* :::** *:*:***. . : . . : . * * :.: : : .:::*: :** *:: : : . . : ", "identical_positions": 127, "similar_positions": 267, "identity": "13.94%" }, { "cls_id": "homologset.oma.831363", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q63416-1", "uniprot_id": "ITIH3_RAT", "id": "Q63416-1", "name": "Inter-alpha-trypsin inhibitor heavy chain H3", "aln": "MVTLWWPCLVLALLSGLETSGFPRSPLRLLGKR-SLPEGVVDGIEIYSTKISCKVTSRFAHNVVTTRAVNRADKAKEVSFDVELPKTAFITNFTLTIDGVTYPGSVKEKEVAQKQYEKAVSQGKTAGLVKASGRKLEKFTVSVNVAAGSKVIFELTYEELLKRNKGKYEMYLKVQPKQLVRHFEIDAHIFEPQGISMLDADASFITNDLLGSALTKSFSGKKGHVSFKPSLDQQRSCPTCTDSLLNGDFTIVYDVNRESPGNVQIVNGYFVHFFAPQGLPVVPKNIAFVIDVSGSMSGRKIQQTREALLKILDDMKEEDYLNFILFSTGVTTWKDHLVKATPANLEEARAFVKNIRDRSMTNINDGLLRGIEMLNKAREDHLVPERSTSILVMLTDGDANTGESRPEKIQENVRNAIRGKFPLYNLGFGNNLNYNFLESLALENHGFARRIYEDSDASLQLQGFYEEVANPLLTNVELEYPENAILDLTRNSYPHFYDGSEIVVAGRLVDRNVDNFKADVKGHGALNDLTFTEEVDMKEMDAALKEQGYIFGDYIERLWAYLTIEQLLEKRKNARGDEKENITAEALELSLKYHFVTPLTSMVVTKPEDNEDQTAIADKPGE--EAISAST--AYLTSQQSSHSPYYY--VDGDPHFIIQVPGKNDTICFNIDEKPGTVLSLIQDPVTGIAVTGQIIGEKGNNASSRTGKTYFGKLGIANAWMDFRIEVTTEKIILGNGDALSTFSWLDTVTVTQTGLSVTINRKKNMVVSFEDGISFVIVLHQVWKKHPVHQDFLGFYVVDSHRMSAQTHGLLGQFFQPFDFKVFDVRPGSDPMKPDATMVVKSHRLTVTRGSQKDYRKDASVGTKVVCWFVHNNGEGFIDGVHTDYIVPSLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61704-1", "uniprot_id": "ITIH3_MOUSE", "id": "Q61704-1", "name": "Inter-alpha-trypsin inhibitor heavy chain H3", "aln": "MRTMWWPCLVLALLSGLETSGFPRSPLQLLGKR-SLPEGVVDGIEVYSTKISCKVTSRFAHNVVTTRAVNRADTAKEVSFDVELPKTAFITNFTLTIDGVTYPGNVKEKEVAQKQYEKAVSQGKTAGLVKASGRKLEKFTVSVNVAAGSKVTFELTYEELLKRNKGKYEMYLKVQPKQLVRHFEIDAHIFEPQGISMLDAEASFITNDLLGSALTKSFSGKKGHVSFKPSLDQQRSCPTCTDSLLNGDFTIVYDVNRESPGNVQIVNGYFVHFFAPQGLPVVPKNIVFVIDVSGSMSGRKIQQTREALLKILDDVKEDDYLNFILFSTDVTTWKDHLVQATPANLKEAKTFVKNIHDQSMTNINDGLLKGIEMLNKAREDHTVPERSTSIIIMLTDGDANTGESRPEKIQENVRNAIGGKFPLYNLGFGNNLNYNFLETLALENHGLARRIYEDSDANLQLQGFYEEVANPLLTNVEVEYPENAILDLTRNSYPHFYDGSEIVVAGRLVDRNMDNFKADVKGHGALNDLTFTEEVDMEEMDAALKEQGYIFGDYIERLWAYLTIEQLLEKRKNAKGDEKENITAEALDLSLKYHFVTPLTSMVVTKPEDNEDQTSIADKPGE--EAIAETTTMSFLTTQQSSQSPYYY--VDGDPHFIIQIPGKNDSICFNIDEKPGTVLRLIQDPVTGITVTGQIIGDKRSNASSRTGKTYFGKLGITNAWMDFRVEVTTEKIILGTGAELSTFSWLDTITVTQTGLSVTINRKKNMVVSFGDGISFVIILHQVWKKHPVHQDFLGFYVVDSHRMSAQTHGLLGQFFQPFDFKVFGIRPGSDPTKPDATMVVKNHRLTVTRGSQKDYRKDASVGTKVICWFVHNNGEGLIDGVHTDYIVPSLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06033-1", "uniprot_id": "ITIH3_HUMAN", "id": "Q06033-1", "name": "Inter-alpha-trypsin inhibitor heavy chain H3", "aln": "MAFAWWPCLILALLSSLAASGFPRSPFRLLGKR-SLPEGVANGIEVYSTKINSKVTSRFAHNVVTMRAVNRADTAKEVSFDVELPKTAFITNFTLTIDGVTYPGNVKEKEVAKKQYEKAVSQGKTAGLVKASGRKLEKFTVSVNVAAGSKVTFELTYEELLKRHKGKYEMYLKVQPKQLVKHFEIEVDIFEPQGISMLDAEASFITNDLLGSALTKSFSGKKGHVSFKPSLDQQRSCPTCTDSLLNGDFTITYDVNRESPGNVQIVNGYFVHFFAPQGLPVVPKNVAFVIDISGSMAGRKLEQTKEALLRILEDMQEEDYLNFILFSGDVSTWKEHLVQATPENLQEARTFVKSMEDKGMTNINDGLLRGISMLNKAREEHRIPERSTSIVIMLTDGDANVGESRPEKIQENVRNAIGGKFPLYNLGFGNNLNYNFLENMALENHGFARRIYEDSDADLQLQGFYEEVANPLLTGVEMEYPENAILDLTQNTYQHFYDGSEIVVAGRLVDEDMNSFKADVKGHGATNDLTFTEEVDMKEMEKALQERDYIFGNYIERLWAYLTIEQLLEKRKNAHGEEKENLTARALDLSLKYHFVTPLTSMVVTKPEDNEDERAIADKPGEDAEATPVSPAMSYLTSYQPPQNPYYY--VDGDPHFIIQIPEKDDALCFNIDEAPGTVLRLIQDAVTGLTVNGQITGDKRGSPDSKTRKTYFGKLGIANAQMDFQVEVTTEKITLWNRAVPSTFSWLDTVTVTQDGLSMMINRK-NMVVSFGDGVTFVVVLHQVWKKHPVHRDFLGFYVVDSHRMSAQTHGLLGQFFQPFDFKVSDIRPGSDPTKPDATLVVKNHQLIVTRGSQKDYRKDASIGTKVVCWFVHNNGEGLIDGVHTDYIVPNLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56652-1", "uniprot_id": "ITIH3_BOVIN", "id": "P56652-1", "name": "Inter-alpha-trypsin inhibitor heavy chain H3", "aln": "MALAQWPYLILALLSGLAVSGFPRNPSLLLGKR-SLPGRAVDGIEVYSTKVNCKVTSRFAHNVVTTRAVNHANTAKEVSFDVELPKTAFITNFTLTIDGVTYPGKVKEKEVAKKQYEKAVSQGKTAGLVKASGRKLEKFTVSVNVAAGSKVTFELTYEELLKRHKGKYEMYLKVQPKQLVKHFEITVDIFEPQGISTLDAEASFITNDLLGSALTKSFSGKKGHVSFKPSLDQQRSCPTCTDSLLKGDFIITYDVNRESPANVQIVNGYFVHFFAPQGLPVVPKSVVFVIDVSGSMHGRKMEQTKDALLKILEDVKQDDYLNFILFSGDVTTWKDSLVPATPENIQEASKFVMDIQDRGMTNINDALLRGISMLNKAREEHTVPERSTSIIIMLTDGDANVGESRPEKIQENVRNAIGGKFPLYNLGFGNNLNYNFLENMALENHGLARRIYEDSDANLQLQGFYEEVANPLLTGVEVEYPQNAILDLTQNSYQHFYDGSEIVVAGRLADEDMNSFKAAVKGHGAINDLTFTEEVDMKEMEKALQERDYIFGDYIERLWAYLTIEQLLDKRKNAQGEEKEILTAQALELSLKYHFVTPLTSMVVTKPEDNENQTAIANKPGEGPLDAEEVPSMAYLTSYQAPQTPYYY--VDGDPHFIIQIPEKDDAICFNIDEDPGTVLRLIQDPVTGLTVNGQIIGEKTGRSDSQTRRTYFGKLGIASAQMDFRIEVTRENITLWNGDSLSTFSWLDTVMVTQDGLSVMINRKKNMVVSFGDGVTFVVVLHQVWKKEPAHHDFLGFYVVNSRGMSAQTHGLLGQFFHPFDFQVSDVHPGSDPTKPDATMVVKNHQLTVTRGSQKDYRKDISVGRNVACWFVHNNGQGLIDGIHRDYIVPNLF", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A8V1AHC2-1", "uniprot_id": "A0A8V1AHC2_CHICK", "id": "A0A8V1AHC2-1", "name": "Inter-alpha-trypsin inhibitor heavy chain H3", "aln": "-MESHLLLCVLLLIPAFASSDFLVTHVRNIKKRNSDNDLVVNGIEIYRMKIDSKVTSRFAHNVITSRAVNRGNIHKEVFFDVELPKTAFITNFSMTIDGITYPGNIKEKEAAKQQYEKAVSRGQTAGLVKASGRKTEKFTVSVNIAAGSKVTFELTYEELLKRHFGKYEMFIKVKPKQLVKDFEIEVNIFEPQGISELEAEGTFITNDLQN-VIKKSFSHKKGHISFKPTLDQQRTCENCSQSLLDGDFIVKYDVKRTTPDNLQIVNGYFVHFFAPTNLPKLPKNVIFIIDISGSMSGREIEQTREALLKILDDIKEDDHFNFILFGSDVHIWKETLIKATPENLDEARKFVRSIDTEGMTNLYGGIMKGIDMLNAAHEGNLVPKRSASIIIMLTDGQPNVGISNTQDIQTHVKKAIEGKYTLYNLGFGYGVDYNFLEKMALENKGLARRIYPDSDSALQLQGFYDEVSNPMLLDVELNYPENEIEDVTKNSFKHFYDGSEIVVAGRFRDINQNSLTVDVKGEGANDVLSFTTQQDKEQTAEVFQEQEYIFGDFIERLWAYLTIEQLLEKRIAATGEEKENFTAKALDLSLKYKFVTPLTSMVVTKPEGNENQAAIADKPTEAQARGAPIVAQASPAHYVHASSPTWYTSVDGDPHFIISVPQKEDAICFNINENPGAVLSLINDPVTGITVNGELIGDKKVDNDAKIQNTYFGKLGIANKHLDIKVTVTPEKITIQNETGKTTFTWLDSVTLKQEGLTLIINKKKSLMLSMSSSASFVIVLHQVWKKHPLHKDFLGLYTLESHKLSAQTQGLLGQFFHPIDFTILEIHSGSDPKKPDATMIFKNKELIVTRGWQKDYRRDPEHGIDIPCWFVHNNGAGLIDGVHTDYIVSSLF", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *:..: *.* . : ** * ..:***:* *:..**********:* ****:.: *** **************::****:****.:****.*::*******:*:*********** ********:****** ***********: *****::**:*****:.*** ..******** *:*:.:****** . .:.**** ****:****:*****:* .*::***.*** : ***:* :* *:************* .** :**.: *:**:**** **:::**::***:**:*::::*::*****. .* **: *: *** *:.** ** .: ..***: ..:::**.*** *:* : :*:**:**::*****:.*.* *..:.** :*::** **:.******* .::*****.:****:*:***** ***: *******:**:**:* .**::**:* * *:*:*:: *************: * : :.:.. ***.** : *:** : * :: .::*: ****::**************:** * *:*** :**.**:*****:**************.**:: :**:** * : : . .* :* *********.:* *:*::****:* **:** **:*.***::*.*:: *:* .:: .********:. :*::: ** *:* : . :**:***:: :.* **:: **:* .:::*: .. :**::*******.* *:****:*.::*: :****:*******:*:** : ::.**** *****::.*.:.* **** *****:* . * .: ******** *:***:* ****..**", "identical_positions": 500, "similar_positions": 242, "identity": "55.93%" }, { "cls_id": "homologset.oma.831364", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5EBC0-1", "uniprot_id": "Q5EBC0_RAT", "id": "Q5EBC0-1", "name": "", "aln": "MKSPAPAHMWNIVLVLLSLLAVLPITTTEKNGIDIYSLTVDSRVSSRFAHTVVTSRVVNRADTVQEATFQVELPRKAFITNFSMIIDGVTYPGVVKEKAEAQKQYTAAVGRGESAGLVKTTGRKTEQFEVSVNVAPGSKTTFELIYQELLQRRLGMYELLLKVRPEQLVKHLQMDIYIFEPQGISTLETESTFMTQELANALTTSQNKTKAHIQFKPTLSQQRKSQNEQDTVLDGDFTVRYDVDRSSTGGTIQIENGYFVHHFAPEDLPTMAKNVLFVIDKSGSMAGKKIQQTREALIKILKDLSTQDQFNIIVFSGEANQWEQLLVQATEENLNRAVDYASKIPAQGGTNINKAVLSAVELLDKSNQAELLPSKSVSLIILLTDGEPTVGETNPKIIQKNTQEAINGRYSLFCLGFGFDVNYPFLEKLALDNGGLARRIYEDSDSALQLQDFYQEVANPLLSSVTFEYPSNAVEDVTRYNFQHHFKGSEMVVAGKLRDQGPDVLLAKVSGQMHLQNITFQTEASIAQQEKEFQGPKYIFHNFMERLWALLTIQQQLEQRISASGAELEALEAQVLNLSLKYNFVTPLTHMVVTKPEDQEQFQVAEKPTEVDGGVWSILSAVQRH-FKTPTTGSKLLTSRLRGNRFQTLSRLGDGLVGSRQYMPP--PGLPGPPGLPGPPGPPGHPH-----FASSIDYGRQPSLGRVLDLPSLSSQDPAGPSLAMLPKVVEQEGTTPEESPNPDHPRAPTIILPLPGSGVDQLCVDILHSEKPMKLFVDINQGLEVVGKYEKN-IGFSWIEVTILKPHLQVHATPERLVVTRGRKNSEYKWKKTLFSVLPGLKMTMDKTGLLQLSGPDKVTISLLSLDDPQRGLMLLLNDTHHFSNDITGELGQFYQDIIWD------DTKQTVRVLGIDYPATRELKLSYQDGFPGTEISCWTVKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6X935-1", "uniprot_id": "ITIH4_MOUSE", "id": "A6X935-1", "name": "Inter alpha-trypsin inhibitor, heavy chain 4", "aln": "MKSPAPAHMWNLVLFLPSLLAVLPTTTAEKNGIDIYSLTVDSRVSSRFAHTVVTSRVVNRADAVQEATFQVELPRKAFITNFSMIIDGVTYPGVVKEKAEAQKQYSAAVGRGESAGIVKTTGRQTEKFEVSVNVAPGSKITFELIYQELLQRRLGMYELLLKVRPQQLVKHLQMDIYIFEPQGISILETESTFMTPELANALTTSQNKTKAHIRFKPTLSQQQKSQSEQDTVLNGDFIVRYDVNRSDSGGSIQIEEGYFVHHFAPENLPTMSKNVIFVIDKSGSMSGKKIQQTREALVKILKDLSPQDQFNLIEFSGEANQWKQSLVQATEENLNKAVNYASRIRAHGGTNINNAVLLAVELLDRSNQAELLPSKSVSLIILLTDGDPTVGETNPTIIQNNVREAINGQYSLFCLGFGFDVNYPFLEKMALDNGGLARRIYEDSDSALQLQDFYHEVANPLLSSVAFEYPSDAVEEVTRYKFQHHFKGSEMVVAGKLQDQGPDVLLAKVSGQMHMQNITFQTEASVAQQEKEFKSPKYIFHNFMERLWALLTIQQQLEQRISASGAELEALEAQVLNLSLKYNFVTPLTHMVVTKPEGQEQFQVAEKPVEVGDGMQRLPLAAQAHPFRPPVRGSKLMT-VLKGSRSQ-IPRLGDAVRASRQYIPPGFPGPPGPPGFPAPPGPPGFPAPPGPPLASGSDFSLQPSYERMLSLPSVAAQYPADPHLVVTEKSKES--TIPEESPNPDHPQVPTITLPLPGSSVDQLCVDILHSEKPMKLFVDPSQGLEVTGKYEN--TGFSWLEVTIQKPHLQVHATPERLVVTRGRKNTEYKWKKTLFSVLPGLKMTMNMMGLLQLSGPDKVTIGLLSLDDPQRGLMLLLNDTQHFSNNVKGELGQFYRDIVWEPPVEPDNTKRTVKVQGVDYLATRELKLSYQEGFPGAEISCWTVEI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14624-1", "uniprot_id": "ITIH4_HUMAN", "id": "Q14624-1", "name": "Inter-alpha-trypsin inhibitor heavy chain H4", "aln": "MKPPRPVRTCSKVLVLLSLLAIHQTTTAEKNGIDIYSLTVDSRVSSRFAHTVVTSRVVNRANTVQEATFQMELPKKAFITNFSMIIDGMTYPGIIKEKAEAQAQYSAAVAKGKSAGLVKATGRNMEQFQVSVSVAPNAKITFELVYEELLKRRLGVYELLLKVRPQQLVKHLQMDIHIFEPQGISFLETESTFMTNQLVDALTTWQNKTKAHIRFKPTLSQQQKSPEQQETVLDGNLIIRYDVDRAISGGSIQIENGYFVHYFAPEGLTTMPKNVVFVIDKSGSMSGRKIQQTREALIKILDDLSPRDQFNLIVFSTEATQWRPSLVPASAENVNKARSFAAGIQALGGTNINDAMLMAVQLLDSSNQEERLPEGSVSLIILLTDGDPTVGETNPRSIQNNVREAVSGRYSLFCLGFGFDVSYAFLEKLALDNGGLARRIHEDSDSALQLQDFYQEVANPLLTAVTFEYPSNAVEEVTQNNFRLLFKGSEMVVAGKLQDRGPDVLTATVSGKLPTQNITFQTESSVAEQEAEFQSPKYIFHNFMERLWAYLTIQQLLEQTVSASDADQQALRNQALNLSLAYSFVTPLTSMVVTKPDDQEQSQVAEKPMEGESRNRNVHSG--STFFKYYLQGAKIPKPEASFSPRRGWNRQ-AGAAGSRMNFRPG-VLSSRQLGLPGPPDVP--------------DHAAYHPFRRLAILPASAPPATSNPDPAVSRVMNMKIEETTMTTQTPAPIQAPSAILPLPGQSVERLCVDPRHRQGPVNLLSDPEQGVEVTGQYEREKAGFSWIEVTFKNPLVWVHASPEHVVVTRNRRSSAYKWKETLFSVMPGLKMTMDKTGLLLLSDPDKVTIGLLFWDGRGEGLRLLLRDTDRFSSHVGGTLGQFYQEVLWGSPAASDDGRRTLRVQGNDHSATRERRLDYQEGPPGVEISCWSVEL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.* *.: . **.* ****: **:*********************************::*******:***:*************:****::******* **:***.:*:***:**:***: *:*:***.***.:* ****:*:***:****:*********:**********:******** ********* :*.:**** ********:********:** .:*:***:*:: :****:*: :**:****:*****:****.*.**.***:*********:*:*********:***.***.:****:* ** **.**. ** *: **:*:* .:*: * * ******.*:* **:*** *** * **. ***********:******** **:*.:**:.*:************.*.****:***********:*************:*******::*:*****:***:**: :*: ************:*:***** *.***:: ********:*:*:** **:.************** ***** *** :***.*: :**. *.***** *.****** ******:.*** ****** * . : . *: *:*: . . : * . .** : * . *:*.**. * *.. . *: **: :. .:.* .: . . : .* :.*: *****..*::**** * : *::*: * .**:**.*:**. ****:***: :* : ***:**::****.*:.: ****:*****:*******: *** **.******.** *. .** ***.**.:**..: * *****::::* : ::*::* * *: **** :*.**:* **.*****:*::", "identical_positions": 572, "similar_positions": 201, "identity": "60.34%" }, { "cls_id": "homologset.oma.831365", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7U5-1", "uniprot_id": "D4A7U5_RAT", "id": "D4A7U5-1", "name": "", "aln": "MPGLYCPTSWTPLPLTDSCVRAYAKGPCLSLRARLTYHNPQPQPVDGVFVYPLAEAEVVSGFEAEAAGRRVSFQLQSRRRLQAACCRALGPGLGTSTPRRCAQGHLVLDLAQARSTLVLPTGLVAADGAMTVTLCSSRELPSRPDGVMHVALPTVFTPLAQPNLPGSPRSPGLCDDSPTSCFGAGSPEEETLSWEQPTAPPDVFSGPARCPAPYTFSFEMLVTGPCLLAGLESPSHALRADALPHASSAATICVTLAEGHQCDRALEILLHPSEPHQPHLMLEAGSLSSAEYEAQVRARHDFQRLQQRDNDGDRQVWFLQRRFHKDILLNPVLVLNFCPDLSAKPGHLNAATRELLFLLDSSGAVHKDAIVLAVKSLPAQTLVNLAIFGTLVQPLFPESRPCSDDTVQLICETIETLQTVSGPPDMLAVLDWALGQPQHRAHPRQLFLLTAASPTVATTHQALEFMRWHRGAARCFSFALAPACHQLLSDLSVLSRGQAYFLRPGERLQPKLVQALRKALEPALSDISVDWFVPDAVEALLTPREIPALYPGDQLLGYCSLFRVDGFRSRALGGQEPGWQSLGGSVFPSPEEVISVTSPGTEPTHTTEPLGTGTVSAELSSPWAIGDSEQSMEALTDPVTDPGPNLSSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPGSTCSSESPGSQGPGSPHGSLPLDPPSQQGCRSLTWVEPAGSRSCPLPVPPPSPFKVGAMSAEVLGRRQRAALAGRSLSSPSGRANPVPGRPRHPSLDAIPDGSGPEPGQQLGQGLDDSGNLLSPAPLDWDMLMEPSFLFKPVPPNGESAPPAEPLPPQAPRCHVVIRALCGEQPMCWEVGVGLEELWGPGDSSQPAPLPMREAAWDQALHRLTAASVVQDNEQLALRGRAETAAEQGRVRRSWLRAIQTSKVSSAPSCFTCPVAVDATTREVLPGALQVWSSDPAEFSGVS-ASQDHLAVAPLSTAVHSKGHQGGCSAGAWDLDLNDNSKSALGESISPTGGHHGLPHQPPASSRLSLGHHRRLCSSNKGQTHENSNEASSHDYLPLVRLQEAPGSFRLDEPFCAAVSIPQERLCRASPFAAHRASLSPTSTSSPWAFLGPGVGQGDSATASCSQPSSSGSEGPGQADSGRGSDTEASERMEERESSDLRGRTWATAVALAWLEHRCAAAFGEWELTASKADCWLRAQRLPDGLDLTALKAAARGLFLLLRHWDQNLQLHLLCYSPSNV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N398-1", "uniprot_id": "VW5B2_HUMAN", "id": "Q8N398-1", "name": "von Willebrand factor A domain-containing protein 5B2", "aln": "MPGLYCPSSWTPLPLTDSWVRACANGPCLSVRARLTYRNPQPQPVDGVFVYPLAEAEVVSGFEAEAAGRRVSFQLQSRRRSQAACCRALGPGLGTPTPRRCAQGHLVLDLAQARSTLVLPTGIIAAAGTMTVTLHSSRELPSRPDGVLHVALPTVLTPLAPPGPPGPPRPPGLCDDSPTSCFGVGSLQEEGLAWEELAAPRDVFSGPARCPAPYTFSFEMLVTGPCLLAGLESPSHALRADAPPHASSAATICVTLAEGHHCDRALEILLHPSEPHQPHLMLEGGSLSSAEYEARVRARRDFQRLQRRDSDGDRQVWFLQRRFHKDILLNPVLALSFCPDLSSKPGHLGTATRELLFLLDSSSVAHKDAIVLAVKSLPPQTLINLAVFGTLVQPLFPESRPCSDDAVQLICESIETLQVPSGPPDVLAALDWAVGQPQHRAYPRQLFLLTAASPMAATTHRTLELMRWHRGTARCFSFGLGPTCHQLLQGLSALSRGQAYFLRPGQRLQPMLVQALRKALEPALSDISVDWFVPDTVEALLTPREIPALYPGDQLLGYCSLFRVDGFRSRPPGGQEPGWQSSGGSVFPSPEEAPSAASPGTEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALTDPVTDPGPNPS-DTAIWRRIFQSSYIREQYVLTHCSASPEPGPGSTGSSESPGSQGPGSPEGSAPLEPPSQQGCRSLAWGEPAGSRSCPLPAPTPAPFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPSPEPGQQLGQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVP--PQAPRCHVVIRGLCGEQPMCWEVGVGLETLWGPGDGSQPPSPPVREAAWDQALHRLTAASVVRDNEQLALRGGAETTADRGHARRCWLRALQTSKVSSAPSCFTCPVAVDATTREVLPGALQVCSSEPAEPPGTPPASHSHLDAAPLPTVVYSKGLQRGSPAGAWDSDQNGNSKRALGDPATPTEGPRRPPPRPP--CRLSMGRRHKLCSPDPGQ--ANNSEGSDHDYLPLVRLQEAPGSFRLDAPFCAAVRISQERLCRASPFAVHRASLSPTSASLPWALLGPGVGQGDSATASCSPSPSSGSEGPGQVDSGRGSDTEASEGAEGLGGTDLRGRTWATAVALAWLEHRCAAAFDEWELTAAKADCWLRAQHLPDGLDLAALKAAARGLFLLLRHWDQNLQLHLLCYSPANV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******:********** *** *:*****:******:****************************************** **************.**************************::** *:***** ************:*******:**** *. **.**.*************.** :** *:**: :** ***************************************** *****************:**********************.**********:****:******:**.***********************.*.******:*****.:************...*************.***:***:******************:******:*****. *****:**.****:*******:************ .****::**:******:******.*.*:*****..**.************:**** ************************:**********************************. ********* **********. *.:******* *:***************** ***** :************ * ********************************** *************.** **:**********:* ***********.*.*:******:*:*****::************.**** ******:***.** **..**********************:********.***..***.** **** * ***********.**************** ******.***.. *:******************:********* ***:*::*:.**.****:******************************** **:*** .*.. **:.** .***.*.*:*** * *..***** * *.*** ***:. :** * : * :** .***:*::::***.: ** *..*.*.******************* ****** *.***********.*********:* ***:**************** ..*********.************ * .:************************.******:*********:*******:*****************************:**", "identical_positions": 1045, "similar_positions": 138, "identity": "83.67%" }, { "cls_id": "homologset.oma.831366", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZP60-1", "uniprot_id": "D3ZP60_RAT", "id": "D3ZP60-1", "name": "", "aln": "MPGLLNCFTGAALPLTASDVTSYVSGYALGLTASLTYGNLEAQPFQGLFVYPTDECTTVVGFEAVIADRVVTIQLRDKAKLDRSYLD---VQSATVTGNLPEEEIPITP-----GKVTLDEDLERILFVVNLGTIAPMENVTIFISTSSELPTLPSGAVRVLLPAICAPTVHPFCAHRFGSSRQQPRGKDPHCFGTQSKDSYKRLCLATLLDTKVTNPMEYEFKFQLEIRGPCLLAGVESPTHEIRADAAPSAHSAKSIIITLAKKHTFDRPVEILLHPSEPHMPHVLVEKGDMTLGEFYQHLKRKADFVRGTKKDNIAERKTEVIRKRLHKDIPHHSVIMLNFCPDLESVQPNPRRTHGEFIFLIDRSSSMSKTNIQCIKEAMLVALKSLMPACLFNVIGFGSTFKTVFASSQIYNEENLALACECIQRMRADMGGTNIFSPLKWVLRQPLRQGHPRLLFLITDGSVNNTGKVLELVRNHASSIRCYSFGIGPTVCYRLVKGLASVSKGSAEFLMEGERLQPKMVKSLKKAMAPVLSDVTVEWVFPETTEALISPVSTSSLFPGERLVGYGIVCDASLYISNSRSDKRRKYGMLHAQESSSSVFYHSQDEGLRPGSGNCAKN----FNQGQTKDAHPCNGDSLSHHGLDGSRRRRAYSTNQISSHKACSRATTASDPTGTTRRYPLRKAKVQDLAHQSSSESQQWQIDLQPLLTRGHDPSQGPRLHGPGARRPSLLPQGCQPMRFSGPEPQAWSPVRELGLGSGRKSVLNSRSSEDLATEPPPFPSTLEPETSSDLEPTAELEEQA-PYRTATPSPVLGKVLVKGVCDNQHMQWEVSFELEPPALRREDTQNDDMWGETFHHLAARAIIREFEHLAQREDEIELGSNRRYQVNAVHTSKACNVISKYTAFVPVDINKRQYLPTVVKYHNSGAL--LSFRNLTRQWKGFSTGLRRSQSMLREHSSAAGDSKFQTLALHESLTSTFNKTPSPGHEKYATAEGPPQNLSTSSLSSTKASEAIFGSRLILNKSRLLTRATKNFLSKSLPKAPEVNPGSQSSDYVPLVSLQLASGAFLLNEVFCRTIQIPMEKLKWTSPFNCLRMSLVTRRHDLKTQSPGDCTSLSSPPPPSDDISLKSGAKDSSDQESSELLEHTGKLWATVVALAWLEHSSASYIIEWELVAAKASSWVELQEVPEGRTLSTIKATARQLFVLLRHWDENLEFNMLCYNPNYM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A9Z1V5-1", "uniprot_id": "VW5B1_MOUSE", "id": "A9Z1V5-1", "name": "von Willebrand factor A domain-containing protein 5B1", "aln": "MPGLLNCLTGAALPLMESDVTSYVSGYALGLTASLTYGNLEAQPFQGLFVYPIDEYSTVVGFEAVIADRVVTIQLRDKAKLDRSHLD---IQPATVTGNFPEEESPIAP-----GKVTLDEDLERVLFVVNLGTIAPMENVTVFISTSSELPTLPSGAVRVLLPAICAPTVPPSCTHRFGSSSPQPQGKDPHCFGTQTKDSYNRLCLATLLDTKVTNPMEYEFKFQLEIRGPCLLAGVESPTHEIRADAAPSAHSAKSIIITLAKKHTFDRPVEILLHPSEPHMPHVLVEKGDMTLGEYDQHLKGKADFIRGTKKDNSAERKTEVIRKRLHKDIPHHSVIMLNFCPDLQSVQPNPRKAHGEFIFLIDRSNSMSKTNIQCIKEAMLVALKSLMPACFFNIIGFGSTFKAVFASSRIYNEENLTMACDCIQRMQADMGGTNMLSPLKWVLRQPLRRGHPRLLFLITDGSVNNTGKVLELVRNHASSTRCYSFGIGPTVCYRLVKGLASVSKGSAEFLMEGERLQPKMVKSLKKAMAPVLSDVTVEWVFPETTEALISPVSTSSLFPGERLMGYGIVCDASLYISNSRSDKRRKYGMLHTQESSSSVFYPSQDEGLSPGSGNCAKN----VNQGQTKDAHPCNGDSPTHHGLDVSRRRRAYSTNQISSHKTCPRATTASDPTGTARRYPLRKAKVQDLASESDWESQKWQTDLQTLLNEGHNLSQGPKLHGPGARRPSLLPQGCQLMRFFDQKPQAWGPVRELDCGASRTSAPNSQSSEDLAIEPAHCPSTFERETSLDLEPMAESEEQANPCRTATPSPVVGKALVKGLCANQRMQWEVSFELEPPALKRGDTQNADMWSETFHHLAARAIIREFEHLAEREDEIELGSNRRYQVNAVHTSKACSVISKYTAFVPVDINKRQYLPTVVKYPNSGAM--LSFRNLTRQWGGSSAGLGRPQSMLREHSSAAGDSKFQTLALQDSPTSTFNKTPSPGHEKQTTAEGPPQNLSASAPSSMKATETLFGSKLNLNKSRLLTRATKGFLSKSLPKASEATPGSQSSDYIPLVSLQLASGAFLLNEAFCTTIQIPMEKLKWTSPFSCLRMSLVTRRQDLKTQSPQDCTSLSSSPPSCDGISLKS--EESSDQESNAMLEHMGKLWATVVALAWLEHSSANYIIEWELVAAKASSWVEKQKVPEGRTLSTLKNTARQLFVLLRHWDEKLEFNMLCYNPNYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TIE3-1", "uniprot_id": "VW5B1_HUMAN", "id": "Q5TIE3-1", "name": "von Willebrand factor A domain-containing protein 5B1", "aln": "MPGLLNWITGAALPLTASDVTSCVSGYALGLTASLTYGNLEAQPFQGLFVYPLDECTTVIGFEAVIADRVVTVQIKDKAKLESGHFDASHVRSPTVTGNILQDGVSIAPHSCTPGKVTLDEDLERILFVANLGTIAPMENVTIFISTSSELPTLPSGAVRVLLPAVCAPTVPQFCTKSTGTSNQQAQGKDRHCFGAWAPGSWNKLCLATLLNTEVSNPMEYEFNFQLEIRGPCLLAGVESPTHEIRADAAPSARSAKSIIITLANKHTFDRPVEILIHPSEPHMPHVLIEKGDMTLGEFDQHLKGRTDFIKGMKKKSRAERKTEIIRKRLHKDIPHHSVIMLNFCPDLQSVQPCLRKAHGEFIFLIDRSSSMSGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSEDSLAMACDDIQRMKADMGGTNILSPLKWVIRQPVHRGHPRLLFVITDGAVNNTGKVLELVRNHAFSTRCYSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMVKSLKKAMAPVLSDVTVEWIFPETTEVLVSPVSASSLFPGERLVGYGIVCDASLHISNPRSDKRRRYSMLHSQESGSSVFYHSQDDGPGLEGGDCAKNSGAPFILGQAKNARLASGDSTTKHDLNLSQRRRAYSTNQITNHKPLPRATMASDPMPAAKRYPLRKARLQDLTNQTSLDVQRWQIDLQPLLNSGQDLNQGPKLRGPGARRPSLLPQGCQPFLPWGQETQAWSPVRER--------TSDSRSPGDL--EPSHHPSAFETETSSDWDPPAESQERASPSRPATPAPVLGKALVKGLHDSQRLQWEVSFELGTPGPERGGAQDADLWSETFHHLAARAIIRDFEQLAEREGEIEQGSNRRYQVSALHTSKACNIISKYTAFVPVDVSKSRYLPTVVEYPNSAALRMLGSRALAQQWRGTSSGFGRPQTMLGEDS-APGNGKFQALNMEASPTALFSEARSPGREKHGASEGPQRSLATNTLSSMKASENLFGSWLNLNKSRLLTRAAKGFLSKPLIKAVESTSGNQSFDYIPLVSLQLASGAFLLNEAFCEATHIPMEKLKWTSPFTCHRVSLTTRPSESKTPSPQLCTSSPPRHPSCDSFSLEPLAKGKLGLEPRAVVEHTGKLWATVVGLAWLEHSSASYFTEWELVAAKANSWLEQQEVPEGRTQGTLKAAARQLFVLLRHWDENLEFNMLCYNPNYV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****** :******* ***** ***************************** ** :**:************:*::*****: .::* ::..*****: :: .*:* ***********:***.************:**********************:***** *:: *:* *.:*** ****: : .*:::*******:*:*:*******:*****************************:**********:***********:***********:*********: **** ::**::* **.. ******:***********************:**** *::***********.*** .:: :*:*************:**:********::*.**: *.*:.*::**: ****:*******::******:***:::*******:****:*************** * *********.**:**********:****:******************************:******.*:****:*********:**********:***.******:*.***:***.***** ***:* .*:**** . **:*:*: ..*** ::*.*: *:**********:.**. .*** **** :::*******::***: ::. : *:** ***.**. *:: .***:*:*************** : . :.***.**** . :*:*. ** **. **::* *** * :* ** :*:* * *.***:**:**.****: .*::******** .*. .* .:*: *:*.*************:**:**:**.*** ********.*:******.:***********:.* :******:* **.*: *. * *::** * *:*: *.*:** *.* *.*:.***:* :. * *: *.:: ***:** ::*** :.*::.: ** **:* :*** * **********:*.****.* ** * ..*.** **:****************.** : :************.* *:**.** : ** ** *** .. *..*.:**:. : . . *. ::** ********.*********.*: *********.**:* *:****** .*:* :*************:************:", "identical_positions": 836, "similar_positions": 244, "identity": "67.91%" }, { "cls_id": "homologset.oma.831367", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1N1Z6-1", "uniprot_id": "F1N1Z6_BOVIN", "id": "F1N1Z6-1", "name": "", "aln": "--------------------------------------------MLPLLGLCFALPLCAGLLEEARSWEDTSDQVGLRIPRQVRLLQRLKTKPLMTEFSVKSTIISRYAFTTVACRMLNRGSEDQEVTFQMQIPAAAFITNFTALIGDKVYQGEITEREKRNGDKVKEKRNKTIEDNGEKGTETFRASAVLPSKDKAAFLLSYEELLQRRLGKYEHVVSVRPQQLVGRLTVEVTVLERPGIAELEVLGLQNSRQRGSGRGPDDSGPPPSTVINQNETFAKVVFKPSVVQQAKIAQNGILGDFIVRYDVNREQSIGDIQVLDGYFVHYFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDHFNIVGFSNRIKVWKDHLVSVTPNSIRDGKVYIHHMSPSGGTDINGALQRGIQLLNDYVAHNDIEDRSVSLVVFLTDGKPTVGETHTLKILNNTREAARGRVCIFTVGIGADVDFKLLEKLSLENCGLTRRVHEDHDARAQLIGFYDEIRTPLLSDIRVDYPPSLVERATRTLFPNYFNGSEIVIAGKLVDRAMDRLHVEVTASNSKKFVVLKKDVPVEPRKVGIDVSQSPRPRGRGQEEPNHLERLWSYLTLKELLSAWLQSIEEPERERLRQEAQALAVNHHFLIPFTSMTLK-SAPRTEAPEAAYGMSSTSMATGPETVMQSLRGTHLQPGPAVKKPYNPRIKISKTSADGDPHFVVDFPLSNLTVCFNIDGEPGHILRLVSDHADSGVTVNGELIGAPAPPNGHKKQRTYFRTITILVNKPERSYLEITPSRVIVDGGDRLVLPCNQSAVVGRRGLEVSVSANASVTVSIQGTVAFVVLLHLYKKPAPYQRNHLGFYIANGQGLSSNCHGLLGQFLNQEARL----IGLSKSPAH-PPVPEAGERSEAVLEVKGRQVPVVWKQRRIYNGEEQVDCWFARNNAAGLIDGEYKGYLAAHPFDSETAFGPGLSQGL----------", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "F1RUM0-1", "uniprot_id": "F1RUM0_PIG", "id": "F1RUM0-1", "name": "", "aln": "--------------------------------------------MLLLLGLCLALPLCAGSLEEAGTWGDTSEQVGLRVPRQVRLLQRLKTKPLMTEFSVKSTIISRYAFTTVSCRMLNRASKDQEVTFQMQIPAAAFITNFTMLIGNQVYQGEITERDEKPGGQVKEKRNKTAEDNGEKGTEMFRASVVLPSKDKAAFFLSYEELLQRRLGKYEHVVSVRPQQLVGRLTVEVNVLERSGIAELEVLRLQNSRRKGSGSGEDDSGPPPSTVIHHNETFAHVVFKPSVVQQAKIAQNGILGDFIVRYDVSREQSIGDIQVLNGYFVHYFAPRDLPPLPKNVVFVLDSSASMVGAKLRQTKDALFTILHDLRPQDHFNIIGFSNRIKVWKDHLVSVTPNNVRDGKVYIHHMSPSGGTDINGALQTGIALLHDSVAPHDLEDRSVSLIVFLTDGKPTVGETHTPKILNNTREAARGRVCIFTVGIGDDVDFRLLEKLSLENCGFTRHVHEDEDAGAQLIGFYDEIRTPLLSDIRVDYPPDAVEQVTRTLFPNYFNGSEIIVAGKLADRAKDRLHVEVTASNSKKFVVLKKDVPVEPRWGGSGGPGGPGPQGGGQEDPNPLERLWSYLTLKELQSSWLQSDQEQERDRLRRKAQALAVAGRFLTPFTSMKLR-PAPQAHTPEATYGLAGMSAAMGPEMVMQSLQGTHLQPGPALKKPYDPRIKISKTSADGDPHFVVDFPRSRLTVCFNIDGQPGDILRLVSDHADSGVTVNGELIGAPAPPHGHKKQRTYFHAITILVNKPQRSYLEITPSRVIVDGGDRQVLPCNQSTVVGSRGLEVSVSANANVTVTVQGTVAFVILFHLYKKPAPYQRNHLGFYIANGQGLSGNCHGLLGQFLNQEARLTEEAAGLSKNPTN-PPVPEAGGRSKAILMVKGHQVPVVWKQRKIYNGEEQVDCWFAGNNAANLIDGEYKDYLAAHPFDSETTFGPGAPRGL----------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q86UX2-1", "uniprot_id": "ITIH5_HUMAN", "id": "Q86UX2-1", "name": "Inter-alpha-trypsin inhibitor heavy chain H5", "aln": "--------------------------------------------MLLLLGLCLGLSLCVGSQEEAQSWGHSSEQDGLRVPRQVRLLQRLKTKPLMTEFSVKSTIISRYAFTTVSCRMLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKVYQGEITEREKKSGDRVKEKRNKTTEENGEKGTEIFRASAVIPSKDKAAFFLSYEELLQRRLGKYEHSISVRPQQLSGRLSVDVNILESAGIASLEVLPLHNSRQRGSGRGEDDSGPPPSTVINQNETFANIIFKPTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQVLNGYFVHYFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWSYLTTKELLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHGMS---AAMGPEPVVQSVRGAGTQPGPLLKKPYQPRIKISKTSVDGDPHFVVDFPLSRLTVCFNIDGQPGDILRLVSDHRDSGVTVNGELIGAPAPPNGHKKQRTYLRTITILINKPERSYLEITPSRVILDGGDRLVLPCNQSVVVGSWGLEVSVSANANVTVTIQGSIAFVILIHLYKKPAPFQRHHLGFYIANSEGLSSNCHGLLGQFLNQDARLTEDPAGPSQNLTH-PLLLQVGEGPEAVLTVKGHQVPVVWKQRKIYNGEEQIDCWFARNNAAKLIDGEYKDYLAFHPFDTGMTLGQGMSREL----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0RAR2-1", "uniprot_id": "M0RAR2_RAT", "id": "M0RAR2-1", "name": "", "aln": "MGGQDWVRAGQSLPRCAHNWFSRSYSNSLKILPGPREVARSGFAMLLLLGLCLGLPLFSESQEEAQIWDDTSEQVMLRVPRQLRLLQRLKTKPLMAEFSVKSTIISRYAFTTVSCRMLNRASEDQDAEFQMQIPESAFITNFTMLIGDNVYQSEITEKEKKSSDRIKEKRNRTTDDNEEKGTDMFKASLVIPSKDKAAFFLSYEELLQRRLGKYEHIISVRPQQLVGRLTVEVNILERSGITSLEVLPLHNSRKKGSGKAEGDEGPPPSTIINHNETFAKVVFKPTVVQQAKIAQNGILGDFIIQYDVKREQNIGDIQVLDGYFVHYFAPKNLPPLPKNVVFVLDISASMVGAKLQQTREALVTILNDLRPQDRFNIIGFSNRIKMWKDHLLPVTPDNIRNGKIYMYHLSPTGGTDINGALQTAIKLLNNYVAQNDIEDRSVSLIIFLTDGKPTFGETNTLRILSNTKEATGGQICIFTVGIGNDVDFRLLEKLSLENCGLTRRVHEEEKAGAQLIGFYDEIRTPLLSDIRIDYPPDAVERVTKTLFPNYFNGSEIVIAGKMADKKFDQLHVEVTASNSKKFVILKRDIPVESRKMGNDVSVTPGSVSGGGKDPNHLERLWSYLTVKELLSSWVQSNSEQEKEQLRQKAQALALNYHFLTPFTSMKLKKPGLHPNQLEDTHGMS---AATGPTTVVQNLREASMQPEPAPKKPYGPRIKISKTSVDGDPHFVVDFPISKLTVCFNIDGEPGDILRLVSDHLGSGVTVNGELIGAPAPPNGHKKHRTYFRTITILINQPERSYLEITPNRVILDGGDRLVLPCNQSMVVGSRGLEVSVSANANVTVTIQGTIAFVILIHLYKKPAPFQRNHLGFYIANSKGLSHNCHGLLGQFLNQDAKLVGAPEEYGKNLSNHQPSPRAEGMPEAILKVKGRRVPVVWKQRKIYNGLEQVDCWFDKNNAAKLIDGVYKDYLALHPFDTESARGPSMSRKAEPDSLHEESA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJD1-1", "uniprot_id": "ITIH5_MOUSE", "id": "Q8BJD1-1", "name": "Inter-alpha-trypsin inhibitor heavy chain H5", "aln": "--------------------------------------------MLLLLGLCLGLPLFSESQEEARSWDDTSEQVVLRVPRQLRLLQRLKTKPLMAEFSVKSTIISRYAFTTVSCRMLNRASEDQEAEFQMQIPESAFITNFTMLIGDSVYRGEITQKDKKSSESVKDKRNRTSDDNEENGSDMFKASLVIPSKDKAAFFLSYEELLQRRLGKYEHSISVRPQQLVGRLTVEVDILERSGITSLEVLPLHNSRKKGSGKAEGDVGPPPSTLINQNETFAKVIFKPTVVQQAKIAQNGILGDFIVRYDVEREQNIGDIQVLNGYFVHYFAPKNLPPLPKNVVFVLDISASMVGAKLQQTREALVTILNDLRPQDRFNIIGFSNRIKMWKDHLLPVTPDNIRNGKIYMYHLSPTGGTDINGALQAAIKLLNNYVAQNDIEDRSVSLIIFLTDGKPTFGETNTLKILSNTKEATRGQICIFTVGIGDDVDFKLLEKLSLENCGLTRRVHEEDKAGAQLIGFYDEIRTPLLSDIRIDYPPDVVEHATKTLFPNYFNGSEIVIAGKMVDKKFDQLHVEVTASNSKKFVILKRDIPVEFRKMGNDVSVTPGSARDGGKDLNHIERLWSYLTVKELLSSWRQSNSEQEKEQLRQKAQDLALNYHFLTPFTSMKLRKPGLRTNQLEDTYGMS---AATGPATVVQNLREAGKQPEPDLKKTYDPRIKISKTSVDGDPHFVVDFPLSKLTVCFNIDGEPGDILRLVSDHLNSGVTVNGELIGAPAPPNGHKKQRTYFRTITILINRPERSYLEITPSRVILDGGDRLVLPCNQSVVVGSRGLEVSVSANANITVVIQGNIAFVILIHLYKNPAPFQRDHLGFYIANSRGLSDNCHGLLGQFLNQDAKLVGAPEEYGKNLSN-QPFPRAEGMPEAILKVKGRRVPVVWKQRKIYNGQAQVDCWFDRNNAAKLIDGVYKDYLASHPFDTESALGLSTPRKPETDRPHEESV", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** *****:.*.* *** * .:*:* **:***:************:*****************:******.*:**: ****** :******* ***:.**:.***::::: . :*:***:* ::* *:*:: *:** *:********:**************** :******* ***:*:* :** .**:.**** *:***::*** . .* ******:*::*****:::***:*****:***********::***.***.*******:*********::************* ******:**:**::**.***:******:*.*:*******:*****:.***:.:*:**:*::*:**:********** .* **:. ** .: ******::********.***:* :**.**:**: *::****:*** ****:***********:**:***:..* :******************:****. * :.*:************::***:.*: *:*************::** *:**. : * . . * . * : * :******** *** *:* ** .* *:::**:.** **: :** *****.*: . : . * ::*:: * ** *:*.:: : ** * **.* *********.*********** *.*********:**.******** .****************:****:***:::****:*:*:********.***:***** ******* *** **********.:** :**.:***:*:****:***:**.********..*** ************:*:* .:. :: .. .:*:* ***::********:**** *:**** **** **** **.*** ****: : * . .: ", "identical_positions": 616, "similar_positions": 200, "identity": "61.6%" }, { "cls_id": "homologset.oma.831371", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q61702-1", "uniprot_id": "ITIH1_MOUSE", "id": "Q61702-1", "name": "Inter-alpha-trypsin inhibitor heavy chain H1", "aln": "MEGATGLR-VLLCLLPL--LTLQARPALGLATGRPRGSEKRHAVDTSVNGVSIKSLKVNCKVTSRFAHYVITSQVVNNADKAREVAFDVEIPKTAFISDFAITSDGKAFIGDIKDKVTAWKQYRKAAVLGESAGLVRASGRNMEQFTIHITVGAQSKATFRLTYEEVLKRRLMQYDITIKVRPKQLVQHFEIDVDIFEPQGISKLDAQASFLSEELAAQTIKKSFSGKKGHVLFRPTVSQQQSCPTCSTSLLNGEFKVTYDVNRDKLCDLLVANNYFTHFFAPKNLTNMSKNLVFVIDISGSMEGQKVRQTKEALLKILEDMRPVDNFDLVLFGSKVQSWKGSLVPASNANLQAAQDFVRRFSLAGATNLNGGLLRGIEILNKAQGSHPELSSPASILIMLTDGEPTEGETDRSQILKNVRNAIRGRFPLYNLGFGHDLDFSFLEVMSTENNGWAQRIYEDHDATQQLQGFYNQVANPLLTDVELQYPQDAVLALTQHRHKQYYDGSEIVVAGRIANHKLNTFKADVRARGEKQEFRATCLVDEEEMKKLLRERGHVLENHVERLWAYLTIQELLAKRMKTEGEERANLSSQVLKMSLDYHFVTPLTSLTIRGLTDEDGLEPTIDKPLEDSQPLEMVGPRRTFVLSAIQPSPTAHPIDSK-LPLRVTGVDTDPHFIIYVPSKEDSLCFNINEEPGVILNLVQDPDTGFTVNGQLIGNKASSPGQHESTYFGRLGISSPTSDFQLEVTPQNITLNPSSSGSMFSWRDQAVLQKDGVVVTINKKRNLVVSVDDGATFEIVLHRTWKGSAVHQDFLGFYVLDSFRMSARTKGLLGQFFSPLDFEVFDLHPGSDPTKTDATMVVKNRQLTVTRGLQKDYSKDPRHGAEVPCWFVHDNGAGLIDGVHTDYVVSDIF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7EYX4-1", "uniprot_id": "F7EYX4_RAT", "id": "F7EYX4-1", "name": "Inter-alpha-trypsin inhibitor heavy chain H1", "aln": "MDGVTGLR-VLLCLL-----TLQTMPALGLATGRPRGNEKRQAVDTTVNGVSIRSLKVNCKVTSRFAHYVITSQVVNSANKAREVAFDVEIPKTAFISDFAMCS--------------------------TQISLGSASGRNMEQFTIHITVGAQSKATFQLTYEEVLKRRLTQYDIVIKVRPKQLVHHFEIDVDIFEPQGISRLDAQASFLSKELAAQTIKKSFSGKKGHVLFRPTVSQQQSCPTCSTSLLNGDFKVTYDVNRDKLCDLLVANNYFTHFFAPQNLTNMSKNLVFVIDISGSMEGQKVKQTKEALLKILGDMKPVDNFDLVLFGSQVQSWKGSLVPASHANLQAAQDFVRRFSLAGATNLNGGLLRGIEILNRAQGSHPELSSPASILIMLTDGEPTEGETDRSQILKNVRNAIRGRFPLYNLGFGHDLDFSFLEVMSIENNGWAQRIYEDHDATQQLQGFYNQVAHPLLTDVELQYPQDAVLALTQHRHKQYYDGSEIVVAGRIADHKLSTFKADVRAHGEKQEFKATCLVDEEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKTEGEERANLSSQILKMSLDYHFVTPLTSMTIRGLTDEDGLEPIIDKPPE-----EMVGPRRTFVLSAAQPSPTAHPIGSK-LPTRVTGVDTDPHFIIYVPTKEDSLCFNINEEPGVILNLVQDPDTGFSVNGQLIGIKAGSPGQHESTYFGRLGVSSPTSDFQLEVTPQNITLNPSSGGPVFSWRDQAVLQKDGVVVTINKKRNLVVSVDDGATFEIVLHRTWRGSSIHQDFLGFYVLDSFRMSARTQGLLGQFFSPLDFEVFDLRPGSDPTKTDATMVVKNRQLTVTRGLQKDYSKDPRHGTEVSCWFVHDNGAGLIDGVHTDYIVSDIF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19827-1", "uniprot_id": "ITIH1_HUMAN", "id": "P19827-1", "name": "Inter-alpha-trypsin inhibitor heavy chain H1", "aln": "MDGAMGPRGLLLCMYLVSLLILQAMPALGSATGRSKSSEKRQAVDTAVDGVFIRSLKVNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPKTAFISDFAVTADGNAFIGDIKDKVTAWKQYRKAAISGENAGLVRASGRTMEQFTIHLTVNPQSKVTFQLTYEEVLKRNHMQYEIVIKVKPKQLVHHFEIDVDIFEPQGISKLDAQASFLPKELAAQTIKKSFSGKKGHVLFRPTVSQQQSCPTCSTSLLNGHFKVTYDVSRDKICDLLVANNHFAHFFAPQNLTNMNKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQGFYSQVAKPLLVDVDLQYPQDAVLALTQNHHKQYYEGSEIVVAGRIADNKQSSFKADVQAHGEGQEFSITCLVDEEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKVDREERANLSSQALQMSLDYGFVTPLTSMSIRGMADQDGLKPTIDKPSEDSPPLEMLGPRRTFVLSALQPSPTHSSSNTQRLPDRVTGVDTDPHFIIHVPQKEDTLCFNINEEPGVILSLVQDPNTGFSVNGQLIGNKARSPGQHDGTYFGRLGIANPATDFQLEVTPQNITLNPGFGGPVFSWRDQAVLRQDGVVVTINKKRNLVVSVDDGGTFEVVLHRVWKGSSVHQDFLGFYVLDSHRMSARTHGLLGQFFHPIGFEVSDIHPGSDPTKPDATMVVRNRRLTVTRGLQKDYSKDPWHGAEVSCWFIHNNGAGLIDGAYTDYIVPDIF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0VCM5-1", "uniprot_id": "ITIH1_BOVIN", "id": "Q0VCM5-1", "name": "Inter-alpha-trypsin inhibitor heavy chain H1", "aln": "----MGLR-GLLCVCLVSLLALQAVAAQGSPTRNPKGGKKRMAVDAAVDGVVIRSLKVNCKVTSRFAHYIITSQVVNSADTAKEVSFNVEIPKTAFISDFAITADENAFTGDIKDKVTAWKQYRKAAISGENAGLVRASGRTMEQFSIHIIVGPRSKATFRLTYEEVLRRKLMQYDIVIKVKPQQLVQHFEIDVDIFEPQGIRKLDVEASFLPKELAAQLIKKSFSGKKGHVLFRPTVSQQQTCPTCSTTLLNGDFKVTYDVNRDDACDLLVANNYFAHFFAPQNLKKLNKNVVFVIDISSSMEGQKLKQTKEALHKILGDMRPGDYFDLVLFGSAVQSWKGSLVQASPANLEAARNFVQQFSLAGATNLNGGLLRGIEILNKAQQSLPELSNHASILIMLTDGEPTEGVMDRTQILKNVRDGIKGRFPLYNLGFGHDVDLNFLEVMSLENNGRVQRIYEDHDATQQLQGFYEQVANPLLRDVELLYPREAVSDLTQHRHKQYYEGSEIMVAGRIADHKLSSFKADVRAHGEGQEFMTTCLVDKEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKLEGQEKANVSAKALQMSLAYQFVTPLTSMTVRGMTDQDGLEPIIDKPLDDYLPLEMVGPRKTFMLQASQPAPTHSSLDIKKLPDQVTGVDTDPHFLIHVPQKEDTLCFNINEEPGVVLSLVQDPDTGFSVNGQLIGNEAGSPGKHEGTYFGRLGIANPATDFQLEVTPQNITLNPGSGGPVFSWRDQAFLRQNEVLVTINRKRNLVVSVEDGGTFEVVLHRVWRGSAVRQDFLGFYVLDSHRMSARTHGLLGQFFHPFDYKVSNLHPGSDPTKTDATMVVKNRRLTVTRGLQKDYRKDPRHGAEVTCWFIHNNGDGLIDGIHTDYIVPDIF", "tax_id": 9913, "tax_name": "Bovine" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * ***: **: .* * .* ..:..:** ***::*:** *:***************::******.*: *:**:*::************: : . .* ****.****:**: *..:**.**:*******:*. **:*.***:*:***:************** :**.:****.:***** **********************:******:****.*******.**. ********:*:*****:**.::.**:*******.**.***::****** *** **:* * *******: ********* ** ***:**::**: *** ****************:.* * ****. **********:**** **:*******:.*:************::*:.****** **** .*****************.***:*** **:* **::** ***::*****:****:******::* .:*****:*:** *** *****:************:*********************** : :*:**:*:: *:*** * *******:::**::*:***:* **** : **:***:**:*.* **:** . . : ** :**********:*:** ***:***********:*.*****:***:******* :* ***:*:.*******::.*::***************. .*.:*******.*::: *:****:********:**.***:****.*:**:::***********.******:******* *:.::* :::*******.******:**:*********** *** **:**.***:*:** ***** :***:*.***", "identical_positions": 621, "similar_positions": 176, "identity": "68.17%" }, { "cls_id": "homologset.oma.831377", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q61703-1", "uniprot_id": "ITIH2_MOUSE", "id": "Q61703-1", "name": "Inter-alpha-trypsin inhibitor heavy chain H2", "aln": "----MQRPVCLLIWLFLLEAQAFEIPINGNSEFAEYSDLVELAPDKLPFVQENGRHQRSLPEESGEETDTVDP----VTLYSYKVQSTITSRVATTTIQSKLVNNSPLPQSVVFDVQIPKGAFISNFTMTVNGMTFTSSIKEKTVGRALYSQARAKGKTAGWVRSRTLDMENFNTEVNIPPGAKVQFELHYQEVKWRKLGSYEHKIHLQPGKLAKHLEVNVWIIEPQGMRFLHVPDTFEGHFQGVPVISKGQQKAHVSFKPTVAQQRKCPNCTETAVNGELVVMYDVNREEKAGELEVFNGYFVHFFAPENLDPIPKNILFVIDVSGSMWGIKMKQTVEAMKTILDDLRTDDQFSVVDFNHNVRTWRNDLVSATKTQIADAKRYIEKIQPSGGTNINEALLRAIFILNEASNMGLLNPDSVSLIILVSDGDPTVGELKLSKIQKNVKQSIQDNISLFSLGIGFDVDYDFLKRLSNENRGIAQRIYGNQDTSSQLKKFYNQVSTPLLRNVQFNYPQASVTDVTQNNFHNYFGGSEIVVAGKFDPSKLTEVQSIITATSANTELVLETLSQMDDLEEFLSKDKHADPDFTKKLWAYLTINQLLAERSLAPTAAIKRKITKTILQMSLDHHIVTPLTAMVIEN--DAGDERMLADSPPQD-HSCCSGALYYGTKVASG----PIPSWANPSPTPMSAMLAVGAKPLESTPPTHLNQVENDPHFIIYLPKSKRNICFNIDSEPGKILSLVSDPESGIVVNGQLIGAKRAENGKLSTYFGKLGFYFQKEGMKIEISTETITLSSGSSTSRLSWSDTAHLGNSRVLISVKKEKSVTLTLNKELFFSVLLHRVWRKHPVNVDFLGIYAPPIDKFSPRVHGLLGQFMQEPAIHIFNERPGKEPGKPEASMEVKGHKLTVTRGLQKDYRTDIVFGTDVPCWFVHNSGKGFIDGHYKDYFVPQLYSFLKRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZVC4-1", "uniprot_id": "A0A8I5ZVC4_RAT", "id": "A0A8I5ZVC4-1", "name": "", "aln": "MSGKMQQLVHLLVWLFLLEARAFEIPINGYSEFAEYDDLVELAPDKLPFVQENRRHQRSLSEDSGEEMDSVDP----VTLYSYKVQSTITSRMATTTIQSKLVNHSPLPQNVVFDVQIPKGAFISNFTMTVNGMTFTSSIKEKTVGRALYSQARAKGKTAGWVRSRTLDMENFNTEVNIPPGAKVQFELHYQEVKWRKLGSYEHKIHLQPGKLAKHLEVNVWIIEPQGMRFLHVPDTFEGHFQGVPVISKGQQKAHVSFKPTVAQQRKCPNCTETAVDGELVVVYDVNREEKAGELEVFNGYFVHFFAPENLDPIPKNILFVIDVSGSMWGIKMKQTVEAMKTILDDLRTEDQFSVVDFNHNVRSWRNDLVSATKTQIADAKRYIEKIQPSGGTNINEALLRAIFILNEASNMGLLNPDSVSLIILVSDGDPTVGELKLSKIQKNVKQNIQDNISLFSLGIGFDVDYDFLKRLSNENRGIAQRIYGNRDTSSQLKKFYNQVSTPLLRNVQFNYPQASVTDVTQNSFHNYFGGSEIVVAGKFDPSKLSEVQSVITATSANTELVLETLSQMDDLEEFLSKDKHADPEFTKKLWAYLTVNQLLTERSLAPTAASKRKITKAILQMSLDHHIVTPLTAMVIEN--DAGDERMLADSPPQD-HSCCSGALYYGTKVASG----PIPSWANPSPTPATAMLAVGAKPLESTPPPHVIRVENDPHFIIYLPKSKKNICFNIDSEPGKILSLVSDPESGLSVNGQLIGAKKTENGKLSTYFGKLGFYFQKEDMKIEISTEAITLSSGSSTSRLSWSDTARLGNERILISVKKEKSVTLTVNKELVFSVLLHRVWKKHPVNVDFLGIYAPPTDKFSPSVHGLLGQFMHEPDIHIFNERPGKEPGKPEASMEVKGHKLTVTRGMQKDYRTNIVFGTDVPCWFVHNSGKGFIDGHYKDYFVPQLYGFLKRP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19823-1", "uniprot_id": "ITIH2_HUMAN", "id": "P19823-1", "name": "Inter-alpha-trypsin inhibitor heavy chain H2", "aln": "----MKRLTCFFICFFLSEVSGFEIPINGLSEFVDYEDLVELAPGKFQLVAENRRYQRSLPGESEEMMEEVDQ----VTLYSYKVQSTITSRMATTMIQSKVVNNSPQPQNVVFDVQIPKGAFISNFSMTVDGKTFRSSIKEKTVGRALYAQARAKGKTAGLVRSSALDMENFRTEVNVLPGAKVQFELHYQEVKWRKLGSYEHRIYLQPGRLAKHLEVDVWVIEPQGLRFLHVPDTFEGHFDGVPVISKGQQKAHVSFKPTVAQQRICPNCRETAVDGELVVLYDVKREEKAGELEVFNGYFVHFFAPDNLDPIPKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIRTWRNDLISATKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVSDGDPTVGELKLSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENHGIAQRIYGNQDTSSQLKKFYNQVSTPLLRNVQFNYPHTSVTDVTQNNFHNYFGGSEIVVAGKFDPAKLDQIESVITATSANTQLVLETLAQMDDLQDFLSKDKHADPDFTRKLWAYLTINQLLAERSLAPTAAAKRRITRSILQMSLDHHIVTPLTSLVIEN--EAGDERMLADAPPQD-PSCCSGALYYGSKVVPD----STPSWANPSPTPVISMLAQGSQVLESTPPPHVMRVENDPHFIIYLPKSQKNICFNIDSEPGKILNLVSDPESGIVVNGQLVGAKKPNNGKLSTYFGKLGFYFQSEDIKIEISTETITLSHGSSTFSLSWSDTAQVTNQRVQISVKKEKVVTITLDKEMSFSVLLHRVWKKHPVNVDFLGIYIPPTNKFSPKAHGLIGQFMQEPKIHIFNERPGKDPEKPEASMEVKGQKLIITRGLQKDYRTDLVFGTDVTCWFVHNSGKGFIDGHYKDYFVPQLYSFLKRP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RH29-1", "uniprot_id": "Q5RH29_DANRE", "id": "Q5RH29-1", "name": "", "aln": "-----MKTVFLLGFLLFYQSWAFEFIIDG--------EWESEMSDPLDHHHDSGRYRRNVLTSGEEEEDFVAIQGNDITVKSYKVESKITSRFAHTKVKSSVVNSGLQAQSIGFNVQIPKRAFINNFTMNVNGITFVGSVKEKTVARNLYAQARARGKAAGIVRTNSQAMETFRTEVHVPAGSKVEFELHYQELMQRKLGIYQHTLHIQPGRLVPLLQVDVYIFEPKGIKFVTAPNTLGKQFEDLTTITHTKEKAHIVFKPNLQQQRKCENCTESAVDGVFTVTYDVERETNAGELQVSDGHFVQFFAPSDLTPLSKNIVFVIDVSGSMWGLKMKQTVEAMKAILDDLSIDDYFSIIDFNHNVRCWSEDLVQASSIQVDEAKKYIQNIKPNGGTNINEALLRAIQMLIKASHHGLIDPRSVSMIILVSDGDPTVGEIKLSTIQKNVKLRMKEEFSLFSLGIGFDVDFDFLERIAMDNRGIAQRIYANQNAAEQLKTFYSQVSSPLLRTITIHFPENTVNNVTQNRFDKFFSGSELIVAGKLQPSDLTTLQSFITASAANMDLNIQAEADIQALDTVLSRHQHSYNDFARQMWGYITVNQLLAERSLARTASRKRKITQRIVALAVEHQFVTPLTAMLVESNEEGRPERLIADSPKDSKHGCCSATGSLSGQMPVQRLVYQNPPWILPTPGPTFVAEAVGSQ--ESIIPVHITGVDSDPHFIINLPKSNMDICFNIDSKPGHILNLISDPGTGVTVNGQLIGSKMLKNNKLNTYFGTISIYSKTDGVQVIVGTDRIDLMESKNNHSFSWGATAELTLNRIKVTILKEQHVTVLIDGRISVMVLLHRVWKKHPVQVDFLGIYMSNNNKYSTQVHGLVGQFAKEPEVKVYDVHEGADPKKKEATMEVKGNKLAVTRGWQKDYRRDRKRGSDIYCWFVHNNGKGFVDGNYTNYILPQLDSFLIAL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :: ::: : .**: *:* : . .. : :. *::*.: .. * : * :*: ****:*.****.* * ::*.:** . .*.: *:***** ***.**:*.*:* ** .*:*****.* **:****:**:** **: : **.*.***:: .*:**:*******: **** *:* :::***:*. *:*:*:::**:*::*: .*:*: :*:.:..*:: ::***: ***.: *** * ** *:**:* :.* ***:** :****:* :*:**:****.:* *:.***:***********:**********:***** :* **::***:*:* * :**:.*:. *: :**:**::*:*.************* :* :*.: **::* ***:*************:***.****** :::::******:*****:***:*:: :*:*******.*::::.***.**.***:****.: :::*. :*.:**** *.::*.***::****::*:.* ::*.***::** :* ::: :::: *: .**:.:*: :*::::*.*:*:****:***** **: **:**: *: ::::*::*****::::*. :. **::**:* :. .***.: . :: *.* *:* * * *:: ** * *: *:.****** ****: :*******:**:**.*:*** :*: *****:*:* :*.**.****.:.:* :.:.::: :.*: * * .... :**. **.: .*: ::: **: **: :: .: . *******:****:******* . :*:*. .***:*** :** ::::: : * :* * **:*****:** :*** ***** : *:*: ******.****:**:*.:*::*** .** ", "identical_positions": 456, "similar_positions": 313, "identity": "47.45%" }, { "cls_id": "homologset.oma.832267", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5HZW3-1", "uniprot_id": "ASPH2_RAT", "id": "Q5HZW3-1", "name": "Aspartate beta-hydroxylase domain-containing protein 2", "aln": "--------------------------MWLEWLVAWSWSLDGLRDCIATGIQSVRDCDGTAVITVACLLVLFVWYCYHVGREQPRPHVSVNSLLQGVDANGLQNGSMYCQSPECVRCTHHDGLNQKLYHNLQEYAKRYSWSGMGRIHKGIREQGRYLSSQPSIQKPEVFFLPDLPTTPYFPRDAQKHDVELLERNFQAILCEFEALYKAFSNCSLPQGWKVNSTPSGEWFTFDFVSQGVCVPRNCRKCPRTYRLLGSLRTCIGNNVFGNACISVLSPGTVITEHYGPTNIRIRCHLGLKTPNGCELVVGGEPQCWAEGRCLLFDDSFLHTSFHEGSAEDGPRVVFMVDLWHPNVAAAERQALDFIFAPGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80VP9-1", "uniprot_id": "ASPH2_MOUSE", "id": "Q80VP9-1", "name": "Aspartate beta-hydroxylase domain-containing protein 2", "aln": "--------------------------MWLEWLVAWSWSLDGLRDCIATGIQSVRDCDGTAVITVACLLILFVWYCYHVGREQPRPHVSVNSLLQGVDANGLQNGSMYCQSPECARCTHHEGLNQKLYHNLQEYAKRYSWSGMGRIHKGIREQGRYLSSQPSIQKPEVFFLPDLPTTPYFSRDAQKHDVELLERNFQAILCEFETLYKAFSNCSLPQGWKVNSTPSGEWFTFDFVSQGVCVPRNCRKCPRTYRLLGSLRTCIGNNVFGNACISVLSPGTVITEHYGPTNIRIRCHLGLKTPNGCELVVGGEPQCWAEGRCLLFDDSFLHTAFHEGSAEDGPRVVFMVDLWHPNVAAAERQALDFIFAPGR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3HTB6-1", "uniprot_id": "G3HTB6_CRIGR", "id": "G3HTB6-1", "name": "Aspartate beta-hydroxylase domain-containing protein 2", "aln": "--------------------------MWLEWLVAWSWSLDGLRDCIATGIQSVRDCDSTAVVTVACLLVMFVWYCYHVGREQPRPHVSVNSLLQGVDASVLQNGSMYCQSPECVRCMHHDGLNQKLYHNLQEYAKRYSWSGMGRIHKAIREQGRYLSSQPSIQKPEVFFLPDLPTTPYFSRDAQKHDVELLERNFQAILCEFETLYKAFSNCSLPQGWKVNSTPSGEWFTFDFVNQGVCVPRNCRKCPRTYRLLGSLRTCIGNNVFGNACISVLSPGTVITEHYGPTNIRIRCHLGLKTPSGCELVVGGEPQCWAEGRCLLFDDSFLHTAFHEGSAEDGPRVVFMVDLWHPNVAAAERQALDFIFAPGR", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q6ICH7-1", "uniprot_id": "ASPH2_HUMAN", "id": "Q6ICH7-1", "name": "Aspartate beta-hydroxylase domain-containing protein 2", "aln": "MVWAPLGPPRTDCLTLLHTPSKDSPKMSLEWLVAWSWSLDGLRDCIATGIQSVRDCDTTAVITVACLLVLFVWYCYHVGREQPRPYVSVNSLMQAADANGLQNGYVYCQSPECVRCTHNEGLNQKLYHNLQEYAKRYSWSGMGRIHKGIREQGRYLNSRPSIQKPEVFFLPDLPTTPYFSRDAQKHDVEVLERNFQTILCEFETLYKAFSNCSLPQGWKMNSTPSGEWFTFYLVNQGVCVPRNCRKCPRTYRLLGSLRTCIGNNVFGNACISVLSPGTVITEHYGPTNIRIRCHLGLKTPNGCELVVGGEPQCWAEGRCLLFDDSFLHAAFHEGSAEDGPRVVFMVDLWHPNVAAAERQALDFIFAPGR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RG81-1", "uniprot_id": "F1RG81_PIG", "id": "F1RG81-1", "name": "Aspartate beta-hydroxylase domain-containing protein 2", "aln": "--------------------------MSLEWLVAWGWSLDGLRDCIATGIQSVRDCDTTAVVTVACLLVLFVWYCYHVGREQPRPYVSVNALMQGPDANGLQNGFVYCQSPECVRCSHNGGLNQKLYHNLQEYAKRYSWSGMGRIHKGIREQGRYLNSRPSIQKPEVFFLPDLPTTPYFSRDAQKHDVELLERNFQTILCEFETLYKAFSNCSLPQGWKMNSTPSGEWVTFYLVNQGVCVPRNCRKCPRTYRLLGSLRTCIGNNVFGNACISVLSPGTVITEHYGPTNIRIRCHLGLKTPGGCELVVGGEPQCWAEGRCLLFDDSFLHTAFHEGSAEDGPRVVFMVDLWHPNVAAAERQALDFIFAPGR", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "E1BAL9-1", "uniprot_id": "E1BAL9_BOVIN", "id": "E1BAL9-1", "name": "Aspartate beta-hydroxylase domain-containing protein 2", "aln": "--------------------------MSLEWLVAWGWSLDGLRDCIAAGIQSVRDCDTTAAVSVACLLALFVWYCYHVGREQPRAYASVNALMQGPDAAGLQNGFVYCQSAECVRCSHSEGLNQKLYHNLQEYAKRYSWSGMGRIHKGIREQGRYLSSRPSIQKPEVFFLPDLPTAPYFSREAQKHDVELLERNFQTILCEFETLYKAFSNCSLPQGWKMNSTPSGEWVTFYLVNQGVCVPRNCRKCPRTYRLLGSLRTCIGNNVFGNACLSVLSPGTVITEHYGPTNIRVRCHLGLKTPSGCELVVGGEPQCWAEGRCLLFDDSFLHTAFHEGPAEDGPRAVFMVDLWHPHVAAAERQALDFIFAPGR", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "E1BSD3-1", "uniprot_id": "E1BSD3_CHICK", "id": "E1BSD3-1", "name": "Aspartate beta-hydroxylase domain-containing protein 2", "aln": "--------------------------MPLVWLPDWSCSLDGLRDFIAAGIQSFRDCDGGALLAVGCLLLLFVWYCYHVGREQPRAYPAVNALMQGAEANGVQNGFVYCHAPECARCSPHDGLNQKLYHNLQEYAKRYSWSGMGRIHKGIREQGRYLNSRPSIQKPEVFFLPDLPTAPYFSRDAQKHDVEVLERNFQTILCEFESLYKAFSNCSLPQGWKMNSTPSGEWFTFYLVNQGMCVPRNCRRCPRTYRLLGSLRTCIGNNVFGNACISVLSPGTVIAEHYGPTNIRIRCHLGLKTPSNCELVVGGEPQCWAEGRCLLFDDSFLHTAFHEGPPEEGPRVVFMVDLWHPNVAAAERQALDFIFAPGR", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * ** *. ******* **:****.**** * ::*.*** :**************.: :**:*:*. :* :*** :**::.**.** ***************************.********.*:****************:***.*:*******:******:******:***************:********.** :*.**:*******:************************:*********:*********:*********..**************************::****..*:***.*********:*****************", "identical_positions": 276, "similar_positions": 47, "identity": "74.8%" }, { "cls_id": "homologset.oma.832269", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q2TA57-1", "uniprot_id": "ASPH1_MOUSE", "id": "Q2TA57-1", "name": "Aspartate beta-hydroxylase domain-containing protein 1", "aln": "------------------------MWKG----GNQEAVIEGSGGELGVPGSWGLQDAACHLARASLPIMFPWPLPLGSSALTMLLGALTSLFLWYCYRLGSQDMQALGTGSRAGGVSGMPDVCSQTG---PRGLGDSGEGPRAEGLVSRRLRAYARRYSWAGMGRVRRAAQGGSGLTGGAGVMGIQRPGLLFLPDLPSSPFVPRDAQRHDVELLQSSFPAILRDFGAVSWDFSGTTPLPRGWSPPLAPGCYQLLLYQAGRCQPSNCRRCPGAYRALRGLRSFMSANTFGNAGFSVLLPGARLEGRCGPTNARVRCHLGLKIPPGCELVVGGEPQCWAEGHCLLVDDSFLHTVAHNGSPEDGPRVVFIVDLWHPNVAGAERQALDFVFAPDP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZWE1-1", "uniprot_id": "D3ZWE1_RAT", "id": "D3ZWE1-1", "name": "", "aln": "------------------------MWKG----GNQEAVIEGSGGELGGPGSWGLQDAAGLLARASLPIMFPWPLPLGSSVLTVLLGALTSLFLWYCYRLGSQDMQALGIGSRAGGVSGMPDVCSQTG---SRGSGDPGEGHRAEGLVSRRLRAYARRYSWAGMGRVRRAAQGGPGLTGGTGILGIQRPGLLFLPDLPSSPFVPRDAQRHDVELLQSSFPAILRDFGAVSWDFSGSTPLPRGWSPPLAPGCYQLLLYQAGRCQPSNCRRCPGAYRALRGLRSFMSANTFGNAGFSVLLPGARLEGRCGPTNARVRCHLGLKIPPGCELVVGGEPQCWAEGHCLLVDDSFLHTVAHNGSPEDGPRVVFIVDLWHPNVAGAERQALDFVFAPDP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3I4I6-1", "uniprot_id": "G3I4I6_CRIGR", "id": "G3I4I6-1", "name": "", "aln": "------------------------MWKG----RNQEAIIEGTGGELGGPGSWGPEDAAGLLARASLTIMFPWPLPLGSSALTVLLGALTSLFLWYCYRLGSQDMQALGAGTRAGSVSGGPDVCSQTG---PRGSGDPGEGPRAEGLVSRRLRAYARRYSWAGMGRVRRAAHGGSGQAGGTGGLGIQRPGLLFLPDLPSSPFVPRDAQRHDVELLQSSFPAILRDFGAVSWDFSGTAPLPRGWSPPLAPGCYQLLLYQAGRCQPSNCRRCPGAYRALRGLRSFMSANTFGNAGFSVLLPGARLEGRCGPTNARVRCHLGLKIPPGCELVVGGEPQCWAEGHCLLVDDSFLHTVAHNGSPEDGPRVVFIVDLWHPNVAGAERQALDFVFAPDP", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q5U4P2-1", "uniprot_id": "ASPH1_HUMAN", "id": "Q5U4P2-1", "name": "Aspartate beta-hydroxylase domain-containing protein 1", "aln": "MKEGRGSFSVERGPRKERETAQSGMWKGNSPAGSQGAAMEGTGGELGGQGNWGPEDAPGLLARASL-IMLPWPLPLASSALTLLFGALTSLFLWYCYRLGSQDMQALGAGSRAGGVRGGPVGCSEAGGPSPGGPGDPGEGPRTEGLVSRRLRAYARRYSWAGMGRVRRAAQGGPGPGRGPGVLGIQRPGLLFLPDLPSAPFVPRDAQRHDVELLESSFPAILRDFGAVSWDFSGTTPPPRGWSPPLAPGCYQLLLYQAGRCQPSNCRRCPGAYRALRGLRSFMSANTFGNAGFSVLLPGARLEGRCGPTNARVRCHLGLKIPPGCELVVGGEPQCWAEGHCLLVDDSFLHTVAHNGSPEDGPRVVFIVDLWHPNVAGAERQALDFVFAPDP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L515-1", "uniprot_id": "ASPH1_BOVIN", "id": "A1L515-1", "name": "Aspartate beta-hydroxylase domain-containing protein 1", "aln": "------------------------MWRGSSAGGSQGAAMEGTGGELGGQGNWGLEDAPGLLARASLPIMPAWPLPLASSALTLLLGALTSLFLWYCYRLGSQDMQALGTGSRAGAVGGRPGGCSEAGRPSPGRSGESGEGPRTEGLMSRRLRAYARRYSWAGMGRVRRAAQGGPSPGGGPGVLGIQRPGLLFLPDLPSAPFVPREAQRHDVELLESSFPAILRDFGAVSWDFSGTTPPPRGWSPPLAPGCYQLLLYQAGRCQPSNCRRCPGAYRALRGLRSFMSANTFGNAGFSVLLPGARLEGRCGPTNARVRCHLGLKIPPGCELVVGGEPQCWAEGHCLLVDDSFLYTVAHNGSPEDGPRVVFIVDLWHPNVAGAERQALDFVFAPDP", "tax_id": 9913, "tax_name": "Bovine" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:* .* * :**:***** *.** :**. ****** ** .*****.**.**:*:*********************** *:***.* * * **::* . *:.*** *:***:***********************:**.. *.* :***************:*****:*********:*******************::* ***************************************************************************************************************:*****************************************", "identical_positions": 304, "similar_positions": 32, "identity": "77.75%" }, { "cls_id": "homologset.oma.832359", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NVH6-1", "uniprot_id": "TMLH_HUMAN", "id": "Q9NVH6-1", "name": "Trimethyllysine dioxygenase, mitochondrial", "aln": "MWYHRLSHLHSRLQDLLKGGVIYPALPQPNFKSLLPLAVHWHHTASKSLTCAWQQHEDHFELKYANTVMRFDYVWLRDHCRSASCYNSKTHQRSLDTASVDLCIKPKTIRLDETTLFFTWPDGHVTKYDLNWLVKNSYE---GQKQKVIQPRILWNAEIYQQAQVPSVDCQSFLETNEGLKKFLQNFLLYGIAFVENVPPTQEHTEKLAERISLIRETIYGRMWYFTSDFSRGDTAYTKLALDRHTDTTYFQEPCGIQVFHCLKHEGTGGRTLLVDGFYAAEQVLQKAPEEFELLSKVPLKHEYIEDVGECHNHMIGIGPVLNIYPWNKELYLIRYNNYDRAVINTVPYDVVHRWYTAHRTLTIELRRPENEFWVKLKPGRVLFIDNWRVLHGRECFTGYRQLCGCYLTRDDVLNTARLLGLQA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0VC74-1", "uniprot_id": "TMLH_BOVIN", "id": "Q0VC74-1", "name": "Trimethyllysine dioxygenase, mitochondrial", "aln": "MWCHRLSHLQSRLQDLLRGRVTRWALQQSNFKSLFPLAIYWHHTASKSLNCVWQQHEDHFELQYANNVMRFDYVWLRDHCRSASCYNSKTHQRSLDTASVDLCIQPQTIHLDETTLFFTWPDGHVTRYDLDWLMKNSYE---GQKQKVIQPRILWNAEIYQQAQVPAVDFQTFLETKEGLKNFLQNFLLYGIAFVENVPPTQKHTEKLAERISLIRETIYGRMWFFTSDFSRGDTAYTKLALDRHTDTTYFQEPCGIQVFHCLKHEGTGGRTLLVDGFYAAEQVLQKAPEEFELLSKVPLKHEYIENVGECQNHMIGVGPVLNIYPWNKELYLIRYNNYDRAVINTVPYDVVHRWYTAHRTLTRELRRPENEFWVKLKPGKVLFIDNWRVLHGRESFTGYRQLCGCYLTRDDVLNTARLLGLQA", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q91ZW6-1", "uniprot_id": "TMLH_RAT", "id": "Q91ZW6-1", "name": "Trimethyllysine dioxygenase, mitochondrial", "aln": "MWYHKLLHQQSRLQNLMKRGDIAHGLRLSGFKSLFPFSLHWCHTASKSVNCTWHQHEDHLELQYASTVMRFDYVWLRDHCRSASCYNSKTHQRSLDTASVDLCIKPKTIRLDESTLFFTWPDGHVTRYDLDWLVKNSYE---GQKQEVIQPRVLWNAKLYQDAQLPSVDFQGFLETKEGLKKFLQNFLLYGIAFVENVPPTQEHTEKLARRVSLIRETIYGRMWYFTSDFSRGDTAYTKLALDRHTDTTYFQEPCGIQVFHCLKHEGTGGRTLLVDGFYAAQQVLQRAPEEFDLLSQVPLKHEYIENVGQCHNHMIGVGPILNIYPWNKELYLIRYNNYDRAVINTVPYDVVRRWYAAHRTLTTELRRPENELWVKLKPGKVLFIDNWRVLHGRESFTGYRQLCGCYLTRDDVLNTARILGLHA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E7F0M9-1", "uniprot_id": "E7F0M9_DANRE", "id": "E7F0M9-1", "name": "Trimethyllysine dioxygenase, mitochondrial", "aln": "---MPLIRVLNRLRGFVS--------RKHGLESLGAQSHRFQHTATHSSSCNYQLLPDCLELNYGGLVMHFDYVWLRDHCRSASCYNSKTNQRNLDTASIDLTIRPSKSRVDEHNLFLTWPDGHVTRYNLAWLAQNSYE---GQMRSAIQPRILWNAHIYSSAKVPAANWDKFMSCDEELKNFLNNFLLYGIAFVEGVPPTLEATETVTQRVSLIRETIYGRMWNFTSDFSRGDTAYTKLALDRHTDTSYFQEPCGIQVFHCLRHEGTGGRTLLVDGFHAADTVLQQTPENFQLLSHVPIKHDYVENLSDHRNHMIGIGPVLNVYPWNNEVYMIRYNNYDRSVINTVPHDVVRRWYVAHRKLTAELRRADNELWVKLKPGKVLFVDNWRVLHGRESFTGLRQLCGCYLTRDDVLNTARSLGLQA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDM7-1", "uniprot_id": "Q9VDM7_DROME", "id": "Q9VDM7-1", "name": "Trimethyllysine dioxygenase, mitochondrial", "aln": "--------------------------------------------------------MLLLKHPKTSQSIEINEFWLRDHCRCVECLNFETNQRRYDVLDLPADIMPLDVKYDGMNLQVQWSDAHKSNYDLDFIFDSQLERLIGRRSKSTNLTPWNRSIILQNERHLRFPLPQLVSSDNEVRSLVESLVRYGIVFIDDVAPTANMTELALRRVFPLMKTFFGEMWTFSDNPDHADTAYTKLYLGSHTDNTYFCDAAGLQALHCIEHSGSGGENFFVDGLHVVHELKRRYPAAYDVLCSVQVPGEYIEKG----EHHYHTAPIIQVDPLTQEFVQLRLNVYDRAVFNTIPQAEMAEFYDSLRQLLLIVRDKQQQWALKLCPGSIVLFDNWRVLHGREAYTGSRTMSGSYVQRTDFLSKARVLGIID", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . :.:: .*******...* * :*:** *. .: * * : * .* . *.*.* :.*:* :: ... * *: . : .: : .. : ::. .: ::.:::.:: ***.*::.*.** : ** .*: : :*::*.** *:.: .:.******* *. ***.:** :..*:*.:**:.*.*:**..::***::... : :: * :::*. * : :*:*. :* .*:::: * .:*. :* * ***:*:**:* : .:* : * * :* ::: :** ** :::.**********.:** * :.*.*: * *.*..** **: ", "identical_positions": 111, "similar_positions": 140, "identity": "26.18%" }, { "cls_id": "homologset.oma.832360", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1N4U6-1", "uniprot_id": "F1N4U6_BOVIN", "id": "F1N4U6-1", "name": "gamma-butyrobetaine dioxygenase", "aln": "---------------------MGCVIQKAEVLDGAHLMR-----------IIWQDGTDS---IYPAVWLRDNCQCPDCYLDSAKARKLLIEALDVYVGIKDLMFDR--KKVHIMWPNDHCSEYGADWLKKRCFSQQAREKLQKELFLPECQYWG-SEFQ-----LPTLDFEDVLK--DDEHAYRWLSSLKKVGIVRLTGAADKRGE---VLKLGKRIGFLYLTFYGH-TWQVQD-KIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQT-----VTGGESEIVDGFNVCQKLKEKNPRAFQILSSTFVDFTDIG--------VDYCDFSVQSKHKIIELDDKDQVVRINFNNATRD----TIFDVPVER--------------------VQPFYAALKEFVDLMNCKDFKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEITRHLEGAYADWDVVMSRLRILRQSLQNRN-", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A4X1SZK1-1", "uniprot_id": "A0A4X1SZK1_PIG", "id": "A0A4X1SZK1-1", "name": "gamma-butyrobetaine dioxygenase", "aln": "---------------------MHCAIQNAEALDGAHLMQ-----------VLWQDGTKS---LFPAVWLRDNCQCPDCYLDSAKARKLLLEALDVNIGIKGLTFDR--KKVHITWPNDHYSEFEADWLKKRCFSQEAREKLQRQLFLPECQYWG-SKFQ-----LPTLDFEDVLK--DDEQAYKWLSSLKKIGIVRLTGASDRRGE---ILKLGKRIGFLYLTFYGH-TWQVQD-KIDANNVAYTTGKLSFHTDYPALHHPPGVQFLHCIKQT-----VTGGDSEIVDGFNVCRKLKEKNPQAFQILSSTFVDFTDIG--------VDYCDFSVQSKHKIIELDDKGQVVRINFNNATRD----TIFDVPVEK--------------------VQPFYAALKEFVDLMNCKDFKFTFKMNPGDVITFDNWRLLHGRQSYEAGTEISRHLEGAYADWDVVMSRLRILRQSVQNRN-", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q924Y0-1", "uniprot_id": "BODG_MOUSE", "id": "Q924Y0-1", "name": "Gamma-butyrobetaine dioxygenase", "aln": "---------------------MHCAILKAEAVDGAHLMQ-----------IFWHDGAES---LYPAVWLRDNCQCSDCYLHSAKARKLLLEALDVNIRIDDLTFDR--KKVYITWPNDHYSEFEANWLKKRCFSQQARARLQGELFLPECQYWG-SELQ-----LPTLNFEDVLN--DDDHAYKWLSSLKKVGIVRLTGAADKRGE---IIKLGKRIGFLYLTFYGH-TWQVQD-KIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQT-----VTGGDSEIVDGFNVCQKLKEKNPQAFHILSSTFVDFTDIG--------VDYCDFSVQSKHKIIELDDKGQVVRVNFNNATRD----TVFDVPIER--------------------VQPFYAALKEFVDLMNSKEYKYTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVTNGN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QZU7-1", "uniprot_id": "BODG_RAT", "id": "Q9QZU7-1", "name": "Gamma-butyrobetaine dioxygenase", "aln": "---------------------MHCAILKAEAVDGARLMQ-----------IFWHDGAES---LYPAVWLRDNCQCSDCYLHSAKARKLLLEALDVNIRMDDLTFDQ--KKVYITWPNGHYSEFEANWLKKRCFSQEARAGLQGELFLPECQYWG-SELQ-----LPTLNFEDVLN--DDDHAYKWLSSLKKVGIVRLTGAADKRGE---IIKLGKRIGFLYLTFYGH-TWQVQD-KIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQT-----VTGGDSEIVDGFNVCQKLKEKNPQAFSILSSTFVDFTDIG--------VDYCDFSVQSKHKIIELDDKGQVVRINFNNATRD----TVFDVPIER--------------------VQPFYAALKEFVDLMNSKEYKYTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVMNGN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8C2LR37-1", "uniprot_id": "A0A8C2LR37_CRIGR", "id": "A0A8C2LR37-1", "name": "Gamma-butyrobetaine dioxygenase", "aln": "---------------------MHCAMLKAEAVDGAHLMQ-----------IFWHDGTES---LYPAVWLRDNCQCSECYLHSAKARKLLLEALDVNIRIKDLSFDR--KKVYITWPNEHYSEFEANWLKKRCFSQQARARLQGVLFLPECQYWG-SELQ-----LPTLNFEDVLK--EDEHAYKWLSTLKKVGIVRLTGAADKCGE---ITKLGKRIGFLYLTFYGH-TWQVQD-KIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQT-----VTGGDSEIVDGFNVCQKLKEKNPQAFHILSSTFVDFTDIG--------IDYCDFSVQSKHKIIELDDKGQVVRINFNNATRD----TIFDVPIER--------------------VQPFYSALKEFVDLMNSKEYKYTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQSVKNGN-", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "O75936-1", "uniprot_id": "BODG_HUMAN", "id": "O75936-1", "name": "Gamma-butyrobetaine dioxygenase", "aln": "---------------------MACTIQKAEALDGAHLMQ-----------ILWYDEEES---LYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDR--KKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWG-SELQ-----LPTLDFEDVLR--YDEHAYKWLSTLKKVGIVRLTGASDKPGE---VSKLGKRMGFLYLTFYGH-TWQVQD-KIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQT-----VTGGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIG--------VDYCDFSVQSKHKIIELDDKGQVVRINFNNATRD----TIFDVPVER--------------------VQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVENGN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VY24-1", "uniprot_id": "Q9VY24_DROME", "id": "Q9VY24-1", "name": "", "aln": "---------------MWVPRLLGRSLSQLKTINSAQFSRQISAKIVNESSIEVQPEANSKPLTFPGIWLRDNCMCEDCFHGSSKSRKLDWDNFDTRIRPVSLQTDEQSKEVLVKWSDAHESRFSLKWLKERCFEPDKQQEYLRDFYRPTTRHWSGAEFQD---IAQHFSYDEVMS--QDSVLMQWLQALAIYGVALLRGAPLDEGV---VRRLADRVGFIRRTTYGE-EFVVQA-KPGAQNFAYLSLTLPLHTDLPYYEYKPSVNILHCVVQTD----SPGGSNMLVDGFHVADLLRRDHPEDFERLSRIVVDWNDIGS-------EDGREFHNIWRAPVICLDEEGRYTRINHSVPQRD----SHFNVPLEE--------------------VLPWYESYALFVRLAIADS--HAFKTRPGDVLTFNNIRLLHGRTGYDDSEESPRYIVGAYLDWDIIYSRLRVLKKRLTASCQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23180-1", "uniprot_id": "AIM17_YEAST", "id": "P23180-1", "name": "Probable oxidoreductase AIM17", "aln": "MLRSNLCRGSRILARLTTTPRTYTSAATAAAANRGHIIKTYFNR--DSTTITFSMEESS----KPVSVCFNNVFLRDASHSAKLVTTGELYHNEKLTAPQDIQISEDGKSLVVKWKDGGHHQFPLQFFIDYKGSSFVSPATRKQESRYRPQLWNKRILKDNVKDLLSVSYNEFIDPKDDSKLFQTLVNLQKFGIAFISGTPSSSSEGLTIQKICERIGPIRSTVHGEGTFDVNASQATSVNAHYANKDLPLHTDLPFLENVPGFQILQSLPATEGEDPNTRPMNYFVDAFYATRNVRESDFEAYEALQIVPVNYIYENGDKRYYQSKPLIEHHDINEDNTLLGNYEALIKCINYSPPYQAPFTFGIYDKPSDLNNNLDLNLITTPAKLTERFLFKSFIRGLNLFESHINDFNNQFRLQLPENCCVIFNNRRILHAN---SLTSSNQQWLKGCYFDSDTFKSKLKFLEEKFPHDK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .:: : : .* * :* :. : . : .: .. *.: : * : .: .:: . . : *. :: ..:::.: *. : * * *:. : *:. . : :: .*:* : * :*. : *: : : * * . *.:*** * . *..::*:.: * . . :**.* . ::... . : *. *:: . :. . : : : :*.. . : :: * : . .: . * . . :: . : *:* *:**.. . . : : *.* * * . *:*:.*.: . ", "identical_positions": 46, "similar_positions": 127, "identity": "9.68%" }, { "cls_id": "homologset.oma.833052", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A3Q1LVT2-1", "uniprot_id": "A0A3Q1LVT2_BOVIN", "id": "A0A3Q1LVT2-1", "name": "", "aln": "MPGYQTGHSSEPGTCVCLKHRMAFNDCFSLSYPGNPRPGDLIEVFRPCYQHWALYLGDGYVINIAPLEDGISPSFTSAKSLFSRKALVKMQLLKDVVGKDTYRINNKYDDTYPPLPVEEVIQRSEFVIGQEVEYDILVNNCEHFVTLLRYGEGVSEQASRAISTIGFVTAAAGAFSFLGLFPKRLRPKFY", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A286ZPI9-1", "uniprot_id": "A0A286ZPI9_PIG", "id": "A0A286ZPI9-1", "name": "", "aln": "---------------------MAFNDCFSLNYPGNPRPGDLIEVFRPGYQHWALYLGDGYVINIAPLEDGISTSFTSAKSIFSTKALVKMQLLKDVVGNDTFRINNKYDDTYAPLPVEEVMQRSEFVIGQEVEYDIFVNNCEHFVTLLRYGAGISEQANRAISTIGFVTAAAGAFSFLGLFPKRLRAKYY", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q9HDD0-1", "uniprot_id": "PLAT1_HUMAN", "id": "Q9HDD0-1", "name": "Phospholipase A and acyltransferase 1", "aln": "---------------------MAFNDCFSLNYPGNPCPGDLIEVFRPGYQHWALYLGDGYVINIAP-VDGIPASFTSAKSVFSSKALVKMQLLKDVVGNDTYRINNKYDETYPPLPVEEIIKRSEFVIGQEVAYNLLVNNCEHFVTLLRYGEGVSEQANRAISTVEFVTAAVGVFSFLGLFPKGQRAKYY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D2KX21-1", "uniprot_id": "PLAT1_RAT", "id": "D2KX21-1", "name": "Phospholipase A and acyltransferase 1", "aln": "---------------------MAVNDCFSLTYPHNPHPGDLIEVFRPCYQHWALYLGDGYVINIAP-VDGIPSSFSSAKSVFSTKALVKMQLLKDVVGNDTYRINNKYDTTYPPLPVEEVIQRSEFAIGQEVTYDLLVNNCEHFVTLLRYGEGVSEQANRAIGTIGLVAAGIDIFTFLGLFPKRQGAKS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZU4-1", "uniprot_id": "PLAT1_MOUSE", "id": "Q9QZU4-1", "name": "Phospholipase A and acyltransferase 1", "aln": "---------------------MAVNDCFSLTYPHNPHPGDLIEVFRPCYQHWALYLGDGYVINIAP-IDGIRSSFTSAKSVFSTKALVKMQLLKDVVGNDTYRINNKYDTTYPPLPVEEVIQRSEFPIGQEVAYDLLVNNCEHFVTLLRYGEGVSEQANRAIGTIGLVAAGIDIFTFLGLFPKRQRTKY-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3I4Z2-1", "uniprot_id": "G3I4Z2_CRIGR", "id": "G3I4Z2-1", "name": "", "aln": "---------------------MAFNDCFSLADPHNPRPGDLIEVFRPGYQHWALYLGDGYVINLTP-IDGVPSPFTSAKSMFSTKALVKMQLLKDVVGNDTYRINNKYDTTYPPLPVDEVIQRSEFAIGQEVAYDLLVNNCEHFVTLLRYGEGVSDQANRAISTIGVVAAAIDIFTFLGLFPKRQRTKY-", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "A0A0R4IY06-1", "uniprot_id": "PLAT1_DANRE", "id": "A0A0R4IY06-1", "name": "Phospholipase A and acyltransferase 1", "aln": "-----------MDNQQRRTDNMASGETDHLQCVEEPQPGDLIEIFRPAYQHWALYLGDGYIINLTPVDEGQATAVSSVKSVFSRKAVVRMQLLKEVVGADSYRINNKYDDDHTPLPVSEIIQRAQMLIGQEVSYDLLGSNCEHFVTLLRYGEGVSEQASRAIGAISLVTAAASAFSVLGLINTRSRNRPF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1C3C1-1", "uniprot_id": "E1C3C1_CHICK", "id": "E1C3C1-1", "name": "", "aln": "---------------------MAANESFSAAHPGDPQPGDLIEIFRPAYQHWALYLGDGYIINVTPVEEGPPATFGSAKSVFSRKAMVRMQLLKEVVGNDTYRINNKYDGTYAPLPVEEIIRRAEYLINQEVSYDLLGNNCEHFVTLLRYGEGVSEQANRAISAIGFVTAAAGAFSLLGLLRSRSRERQY", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** .: :* ******:*** ************:**::* :* ... *.**:** **:*:*****:*** *::******* :.****.*:::*:: *.*** *::: .************ *:*:**.***.:: .*:*. . *:.***: . : ", "identical_positions": 88, "similar_positions": 46, "identity": "46.32%" }, { "cls_id": "homologset.oma.833053", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P53816-1", "uniprot_id": "PLAT3_HUMAN", "id": "P53816-1", "name": "Phospholipase A and acyltransferase 3", "aln": "MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNELRYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A5G2QV43-1", "uniprot_id": "A0A5G2QV43_PIG", "id": "A0A5G2QV43-1", "name": "", "aln": "MRALIPEPQLGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEIAGAGAASLMSALTDKALVKKELLYEVAGRDRYQVNNKHDGKYSPLPPSKIVQRAEELVGQEVLYKLTSENCEHFVNELRYGVARSDQVRDAIVAAGIAGVGLAAVSFIGVMLSRNKRQKQ", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q8R3U1-1", "uniprot_id": "PLAT3_MOUSE", "id": "Q8R3U1-1", "name": "Phospholipase A and acyltransferase 3", "aln": "MLAPIPEPKPGDLIEIFRPMYRHWAIYVGDGYVIHLAPPSEIAGAGAASIMSALTDKAIVKKELLCHVAGKDKYQVNNKHDEEYTPLPLSKIIQRAERLVGQEVLYRLTSENCEHFVNELRYGVPRSDQVRDAVKAVGIAGVGLAALGLVGVMLSRNKKQKQ", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * ****: *********:*************:*******:*******:********:****** .*** *:******** :*:*** ***:****.********:*****************.*******.: *..:**:****:.::***:****:***", "identical_positions": 128, "similar_positions": 26, "identity": "79.01%" }, { "cls_id": "homologset.oma.833055", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JI60-1", "uniprot_id": "LRAT_MOUSE", "id": "Q9JI60-1", "name": "Lecithin retinol acyltransferase", "aln": "MKNPMLEAASLLLEKLLLISNFKLFSVSVPGGGT--GKNRPYEISSFVRGDVLEVSRTHFIHYGIYLGENRVAHLMPDILLALTNDKERTQKVVSNKRLLLGVICKVASIRVDTVEDFAYGADILVNHLDGTLKKKSLLNEEVARRAEQQLGLTPYSLLWNNCEHFVTYCRYGSRISPQAEKFYDTVKIIIRDQRSSLASAVLGLASIVYTGLASYMTLPAICIPFCLWMMSG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JI61-1", "uniprot_id": "LRAT_RAT", "id": "Q9JI61-1", "name": "Lecithin retinol acyltransferase", "aln": "MKNSMLEAASLLLEKLLLISNFKIFSVCAPGGGT--GKKHPYEINSFLRGDVLEVSRTHFTHYGIYLGDNRVAHLMPDILLALTSDKERTQKVVSNKRLLPGVICKVASIRVDTVEDFAYGADILVNHLDETLKKKSLLNEEVARRAEQQLGLTPYSLLWNNCEHFVTYCRYGSPISPQAEKFHETVKILIRDQRSCLASAVLGLVSIIYTGLASYMTLPAVCIPFCLWMMSG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A3L7IGP5-1", "uniprot_id": "A0A3L7IGP5_CRIGR", "id": "A0A3L7IGP5-1", "name": "Lecithin retinol acyltransferase", "aln": "MKNPMLEAVSLLLEKLLLISNIKLFSVSTPGGGT--EKNRPYEISSFLRGDVLEVSRTHFTHYGIYLGNNRVAHLMPDILLALTNDEGRTQKVVSNKRLIPGVICKVASIRVDTVEDFAYGADILVNHLDETLKKKSLLNEVVACRAEQQLGMTPYSLLWNNCEHFATYCRYGAPISPQAEKFHETVKTIIRDQRSCLASAVLGLLSIVYTGLASYMTLPAICIPFCLWMMSG", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "O95237-1", "uniprot_id": "LRAT_HUMAN", "id": "O95237-1", "name": "Lecithin retinol acyltransferase", "aln": "MKNPMLEVVSLLLEKLLLISNFTLFSSGAAGEDK--GRNSFYETSSFHRGDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVASIRVDTVEDFAYGANILVNHLDESLQKKALLNEEVARRAEKLLGFTPYSLLWNNCEHFVTYCRYGTPISPQSDKFCETVKIIIRDQRSVLASAVLGLASIVCTGLVSYTTLPAIFIPFFLWMAG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RYR6-1", "uniprot_id": "F1RYR6_PIG", "id": "F1RYR6-1", "name": "Lecithin retinol acyltransferase", "aln": "MKNPMLEAVSLVLEKLLLISNFRLFSSGAPGEDK--TRNTFYEISSYLRGDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDKELTQKVVSNKRLILGVICRVASIRVDTVEDFAYGADILVNHLDRSLKKKALLNEEVARRAEKQLGLSSYSLLWNNCEHFVTYCRFGTAISPQADKFCENVKIIIRDQRSVLASAVLGLASIVCLGLAPYTTLPAIFIPFCLWMAG-", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "F1P4T5-1", "uniprot_id": "F1P4T5_CHICK", "id": "F1P4T5-1", "name": "Lecithin retinol acyltransferase", "aln": "MKNAVPQVASLLLEKLLLLVHVRALPAGTEGGESPPAASGYYDTSCFRRGDLLEVPRTLFVHFGIYLGENRVAHLMPDILPAFTDDHRQIQRVVTNKRLILGVITKTASIRVDTVEDFAYGGSILVNHMDRLFKDQVLGSEEAACRAEMLVGATAYSLLWNNCEHFVTYCRYGAPVSFQTDKFCETVKMIIRDQRSVLASVLVGLASIICLGLAPSTALPTIFITFVLWMAG-", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "F1Q7T8-1", "uniprot_id": "F1Q7T8_DANRE", "id": "F1Q7T8-1", "name": "", "aln": "----MLDSLTFLFEKFFLFSNFNLFKSIWQPEKE---ECAVKCHPALRRGDLLEVQRTLFIHYGIYLGENRVAHLMPDIMPLLTSNKQHIKPVVTNKRLILGCMYRLASIRVDSVEDFAYGAPILTNDMDKKMKCQVLANEEVARRAEKLVGDIPYSLLWNNCEHFVTYCRYGTPVSEQTDKFCNCLKSIIRDQRSVALTIGMGVMYILCFGLAPSTTLPTILIPFILWMAG-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ::::**::*: :. : . ***:*** ** : *:*****:*****:****: :*.: : **:****: * : : ******:*******. **.*.:* :: : * .* .* *** :* .***********.****:*: :* *::** : :* :****** : :*: *: **.. :**:: *.* *** . ", "identical_positions": 96, "similar_positions": 59, "identity": "41.2%" }, { "cls_id": "homologset.oma.833056", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0R4INS8-1", "uniprot_id": "A0A0R4INS8_DANRE", "id": "A0A0R4INS8-1", "name": "", "aln": "MNKFDKKPQPGDLIEIFRGIYQHWAIYVGDGYVIHLVPPSEYAHAGANSMMSVLHERAKVKKENLYEVVGDHDYRINNFLDDKYEPRPIHEILQDAYSVLGQERSYSVFSGNCEHFVTELRYGKAHSRQVRKAV-EMGVAAGISFGVLAYAVVKIFGSNNKEKQTQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NWW9-1", "uniprot_id": "PLAT2_HUMAN", "id": "Q9NWW9-1", "name": "Phospholipase A and acyltransferase 2", "aln": "MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAGL---LAAASLVGILLARSK-RERQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :*: ****** * * ***********:**.*.** * *** *::*.* ::* **** * *.*..:**:** **:* * * ::*:: * .::*** .**: *.******..**** ::* ** ** :*****: : * ::* *: :..* :: *", "identical_positions": 83, "similar_positions": 41, "identity": "50.0%" }, { "cls_id": "homologset.oma.834037", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q66HC3-1", "uniprot_id": "CI072_RAT", "id": "Q66HC3-1", "name": "Guanine nucleotide exchange factor C9orf72 homolog", "aln": "MSTICPPPSPAVAKTEIALSGESPLLAATFAYWDNILGPRVRHIWAPKTDQVLLSDGEITFLANHTLNGEILRNAESGAIDVKFFVLSEKGVIIVSLIFDGNWNGDRSTYGLSIILPQTELSFYLPLHRVCVDRLTHIIRKGRIWMHKERQENVQKIVLEGTERMEDQGQSIIPMLTGEVIPVMELLASMRSHSVPEDLDIADTVLNDDDIGDSCHEGFLLNAISSHLQTCGCSVVVGSSAEKVNKIVRTLCLFLTPAERKCSRLCEAESSFKYESGLFVQGLLKDATGSFVLPFRQVMYAPYPTTHIDVDVNTVKQMPPCHEHIYNQRRYMRSELTAFWRATSEEDMAQDTIIYTDESFTPDLNIFQDVLHRDTLVKAFLDQVFHLKPGLSLRSTFLAQFLLILHRKALTLIKYIEDDTQKGKKPFKSLRNLKIDLDLTAEGDLNIIMALAEKIKPGLHSFIFGRPFYTSVQERDVLMTF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DFW0-1", "uniprot_id": "CI072_MOUSE", "id": "Q6DFW0-1", "name": "Guanine nucleotide exchange factor C9orf72 homolog", "aln": "MSTICPPPSPAVAKTEIALSGESPLLAATFAYWDNILGPRVRHIWAPKTDQVLLSDGEITFLANHTLNGEILRNAESGAIDVKFFVLSEKGVIIVSLIFDGNWNGDRSTYGLSIILPQTELSFYLPLHRVCVDRLTHIIRKGRIWMHKERQENVQKIVLEGTERMEDQGQSIIPMLTGEVIPVMELLASMKSHSVPEDIDIADTVLNDDDIGDSCHEGFLLNAISSHLQTCGCSVVVGSSAEKVNKIVRTLCLFLTPAERKCSRLCEAESSFKYESGLFVQGLLKDATGSFVLPFRQVMYAPYPTTHIDVDVNTVKQMPPCHEHIYNQRRYMRSELTAFWRATSEEDMAQDTIIYTDESFTPDLNIFQDVLHRDTLVKAFLDQVFHLKPGLSLRSTFLAQFLLILHRKALTLIKYIEDDTQKGKKPFKSLRNLKIDLDLTAEGDLNIIMALAEKIKPGLHSFIFGRPFYTSVQERDVLMTF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96LT7-1", "uniprot_id": "CI072_HUMAN", "id": "Q96LT7-1", "name": "Guanine nucleotide exchange factor C9orf72", "aln": "MSTLCPPPSPAVAKTEIALSGKSPLLAATFAYWDNILGPRVRHIWAPKTEQVLLSDGEITFLANHTLNGEILRNAESGAIDVKFFVLSEKGVIIVSLIFDGNWNGDRSTYGLSIILPQTELSFYLPLHRVCVDRLTHIIRKGRIWMHKERQENVQKIILEGTERMEDQGQSIIPMLTGEVIPVMELLSSMKSHSVPEEIDIADTVLNDDDIGDSCHEGFLLNAISSHLQTCGCSVVVGSSAEKVNKIVRTLCLFLTPAERKCSRLCEAESSFKYESGLFVQGLLKDSTGSFVLPFRQVMYAPYPTTHIDVDVNTVKQMPPCHEHIYNQRRYMRSELTAFWRATSEEDMAQDTIIYTDESFTPDLNIFQDVLHRDTLVKAFLDQVFQLKPGLSLRSTFLAQFLLVLHRKALTLIKYIEDDTQKGKKPFKSLRNLKIDLDLTAEGDLNIIMALAEKIKPGLHSFIFGRPFYTSVQERDVLMTF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A287AZU9-1", "uniprot_id": "A0A287AZU9_PIG", "id": "A0A287AZU9-1", "name": "", "aln": "MSTLCPPPSPAVAKTEIALSGESPLLAATFAYWDNILGPRVRHIWAPKTEQVLLSDGEITFLANHTLNGEILRNAESGAIDVKFFVLSEKGVIIVSLIFDGNWNGDRSTYGLSIILPQTELSFYLPLHRVCVDRLTHIIRKGRIWMHKERQENVQKIVLEGTERMEDQGQSIIPMLTGEVIPVMELLSSMKSHSVPEEIDIADTVLNDDDIGDSCHEGFLLNAISSHLQTCGCSVVVGSSAEKVNKIVRTLCLFLTPAERKCSRLCEAESSFKYESGLFVQGLLKDSTGSFVLPFRQVMYAPYPTTHIDVDINTVKQMPPCHEHIYNQRRYMRSELAAFWRATSEEDMAQDTVIYTDESFTPDLNIFQDVLHRDTLVKAFLDQVFHLKPGFSLRSTFLAQFLLVLHRKALTLIKYIEDDTQKGKKPFKSLRNLKVDLDLTAEGDLNIIMALAEKIKPGLHSFIFGRPFYTSVQERDVLMTF", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A8V0XPZ0-1", "uniprot_id": "A0A8V0XPZ0_CHICK", "id": "A0A8V0XPZ0-1", "name": "", "aln": "MSALCPPPSPAVAKTEISMNGESPLLAATFAYWDNILGPRVRHIWAPKTDQVLLSDGEITFLANHTLNGEILRNAESGAIDVKFFVLAEKRVIIVSLIFDGNWNGDRSTYGLSIILPQSELAFYLPLHRVCVDRLTHIIRKGRIWMHKERQEHFQKIVLEGTERMEDQGQSIIPMLTGEVIPVMELLSSMKSHSVPEEIDISDTVLNDDDIGDSCHEGFLLNAISSHLQTCGCSVVVGSSAEKVNKIVRTLCLFLTPSERKCSRLCRSESSFKYESGLFVQGLLKDATGSFVLPFRQVMYAPYPTTHIDVDVNTVKQMPPCHEHIYNQRRYMRSELTAFWRANSDEEMSQDPIIHTDESFTPDLNVFQDILHRDTLVKAFLDQIFHLKPGLSLRSTFLAQFLLVLHRKALTLIKYIEDDTQKGKKPFKSLRSLKIDLDLTAEGDLNIIMALAEKIKPGLHSFIFGRPFYISVQERDMLMTF", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::*************::.*:***************************:*************************************:** ***************************:**:******************************:.***:*****************************:**:******::**:*******************************************************:********.:******************:************************:************************:*****.*:*:*:**.:*:**********:***:*************:*:****:************:***************************.**:********************************** ******:****", "identical_positions": 439, "similar_positions": 40, "identity": "91.27%" }, { "cls_id": "homologset.oma.834049", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7M0-1", "uniprot_id": "G3V7M0_RAT", "id": "G3V7M0-1", "name": "CCR4-NOT transcription complex subunit 1", "aln": "--------------------------------------------------------------------------------------MNLDSLSLALS-QISYLVDNLTKKNYRASQQEIQHIVNRHGPEADRHLLRCLFSHVDFSGD--------------------------------GKSSGKDFHQTQFLIQECASLITKPNFISTLSYAIDNPLHYQKSLKPAPHLFAQLSKVLKLSKVQEVIFGLALLNSSSPDLRGFAAQFIKQKLPDLLRSYIDADVSGNQEGGFQDIAIEVLHLLLSHLLFGQKGAFGVGQEQIDAFLKTLRRDFPQER------------------------CPVVLAPLLYPEK------------RDILMDRILPDSGGVAKTMMESSLADFMQEVGYGFCASIEECRNIIMQFG-VREVTAAQVARVLGMMAR---------------------------------------THSGLTDGIPLQSISAPGSGIWSDGKDKSEGAQAHTWNVEVLIDVLKELNPSLNFKEVTYELDHPGFQIRDSKGLHNVVYGIQRG-----LGMEVFPVDFIYR-PWKHAEGQLSFIQHSLINP-EVFCFADYPCHTVATDILKAPPEDDNREIATWKSLDLIESLLRLAEVG--QYEQVKQLFSFPIKHCPDMLVLALLQINTSWHTLRHELISTLMPIFLGNHPNSAIILHYAWHGQGQSPSIRQLIMHAMAEWYMRGEQYDQAKLSRILDVAQDLKALSMLLNGTPFAFVIDLAALASRREYLKLDKWLTDKIREHG-EPFIQACMTFLKRRCPSILGGLAPEKDQPKSAQLPAETLATMLACLQACAGSVSQELSETILTMVANCSNVMNKARQPPPGVMPKGRPPSASSLDAISPVQIDPLAGMASLSIGGSAAPHTQSMQGFPPNLGSAFSTPQSPAKAFPPLSTPNQTTAFSGIGGLSSQLPVGGLGTGSLTGIGTGALGLPAVNSDPFVQRKLGTSGLNQPTFQQSKMKPSDLSQVWPEANQHFSKEIDDEANSYFQRIYNHPPHPTMSVDEVLEMLQRFKDSTIKREREVFNCMLRNLFEEYRFFPQYPDKELHITACLFGGIIEKGLVTYMALGLALRYVLEALRKPFGSKMYYFGIAALDRFKNRLKDYPQYCQHLASISHFMQFPHHLQEYIEYGQQSRDPPVKMQGSITTPGSIALAQAQAQAQVPAKAPLAGQVNTMVTTSTTTTVAKTVTVTKPTGVSFKKDVPPSINTTNIDTLLVATDQTERIVEPP-ENIQEKIAFIFNNLSQSNMTQKVEELKETVKEEFMPWVSQYLVMKRVSIEPNFHSLYSNFLDTLKNPEFNKMVLNETYRNIKVLLTSDKAAANFSDRSLLKNLGHWLGMITLAKNKPILHTDLDVKSLLLEAYVKGQQELLYVVPFVAKVLESSIRSLVFRPPNPWTMAIMNVLAELHQEHDLKLNLKFEIEVLCKNLALDINELKPGNLLKDKDRLKNLDEQLSAPKKDVKQPEELPAITTTTTSTTPATSTTCTATV-------------------------------------------------PPQPQYSYHDINVYSLAGLAPHITLNPTIPLFQAHPQLKQCVRQAIERAVQELVHPVVDRSIKIAMTTCEQIVRKDFALDSEESRMRIAAHHMMRNLTAGMAMITCREPLLMSISTNLKNSFASALRTASPQQREMMDQAAAQLAQDNCELACCFIQKTAVEKAGPEMDKRLATEFELRKHARQEGRR---YCDPVVLTYQAERMPEQIRLKVGGVDPKQLAVYEEFARN----------------VPGFLPTNDLSQP------TGFLAQPMKQAWATDDVAQIYDKCITELEQHLHAIPPTLAMNPQAQALRSLLEVVVLSRNSRDAIAALG------------------------------------------LLQKAVEGLLDATSGADADLLLRYRECHLLVLKGLQDGR----AYGSPWCN-----------------------------KQITRCLIECRDEYKYNVEAVELLIRNHLVNMQQYDLHLAQSMENGLNYMAVAFAMQLVKILLVDERSVAHITEADLFHTIETLMRINAHSRGNAPEGLPQLMEVVRS----------------NYEAMIDRAHGGPNFMMHSGISQASEYDDPPGLREKAEYLLREWVNLYHSAAAGRDSTKAFSAFVGQMHQQGILKTDDLITRFFRLCTEMCVEISYRAQAEQQHNPAANPTMIRAKCYHNLDAFVRLIALLVKHSGEATNTVTKINLLNKVLGIVVGVLLQDHDVRQSEFQQLPYHRIFIMLLLELNAPEHVLETINFQTLTAFCNTFHILRPTKAPGFVYAWLELISHRIFIARMLAHTPQQKGWPMYAQLLIDLFKYLAPFLRNVELTKPMQILYKGTLRVLLVLLHDFPEFLCDYHYGFCDVIPPNCIQLRNLILSAFPRNMRLPDPFTPNLKVDMLSEINIAPRILTNFTGVMPP-QFKKDLDSYLKTRSP-VTFLSDLRSNLQVSNE------PGNRYNLQLINALVLYVGTQAIAHIHNKGSTPSMSTITHSAHMDIFQNLAVDLDTEGRYLFLNAIANQLRYPNSHTHYFSCTMLYLFAEANTEAIQEQITRVLLERLIVNRPHPWGLLITFIELIKNPAFKFWNHEFVHCAPEIEKLFQSVAQCCMGQKQAQQVMEGTGAS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZQ08-1", "uniprot_id": "CNOT1_MOUSE", "id": "Q6ZQ08-1", "name": "CCR4-NOT transcription complex subunit 1", "aln": "--------------------------------------------------------------------------------------MNLDSLSLALS-QISYLVDNLTKKNYRASQQEIQHIVNRHGPEADRHLLRCLFSHVDFSGD--------------------------------GKSSGKDFHQTQFLIQECASLITKPNFISTLSYAIDNPLHYQKSLKPAPHLFAQLSKVLKLSKVQEVIFGLALLNSSSPDLRGFAAQFIKQKLPDLLRSYIDADVSGNQEGGFQDIAIEVLHLLLSHLLFGQKGAFGVGQEQIDAFLKTLRRDFPQER------------------------CPVVLAPLLYPEK------------RDILMDRILPDSGGVAKTMMESSLADFMQEVGYGFCASIEECRNIIMQFG-VREVTAAQVARVLGMMAR---------------------------------------THSGLTDGIPLQSISAPGSGIWSDGKDKSEGAQAHTWNVEVLIDVLKELNPSLNFKEVTYELDHPGFQIRDSKGLHNVVYGIQRG-----LGMEVFPVDFIYR-PWKHAEGQLSFIQHSLINP-EVFCFADYPCHTVATDILKAPPEDDNREIATWKSLDLIESLLRLAEVG--QYEQVKQLFSFPIKHCPDMLVLALLQINTSWHTLRHELISTLMPIFLGNHPNSAIILHYAWHGQGQSPSIRQLIMHAMAEWYMRGEQYDQAKLSRILDVAQDLKALSMLLNGTPFAFVIDLAALASRREYLKLDKWLTDKIREHG-EPFIQACMTFLKRRCPSILGGLAPEKDQPKSAQLPAETLATMLACLQACAGSVSQELSETILTMVANCSNVMNKARQPPPGVMPKGRPPSASSLDAISPVQIDPLAGMASLSIGGSAAPHTQSMQGFPPNLGSAFSTPQSPAKAFPPLSTPNQTTAFSGIGGLSSQLP-GGLGTGSLTGIGTGALGLPAVNNDPFVQRKLGTSGLNQPTFQQSKMKPSDLSQVWPEANQHFSKEIDDEANSYFQRIYNHPPHPTMSVDEVLEMLQRFKDSTIKREREVFNCMLRNLFEEYRFFPQYPDKELHITACLFGGIIEKGLVTYMALGLALRYVLEALRKPFGSKMYYFGIAALDRFKNRLKDYPQYCQHLASISHFMQFPHHLQEYIEYGQQSRDPPVKMQGSITTPGSIALAQAQAQAQVPAKAPLAGQVNTMVTTSTTTTVAKTVTVTKPTGVSFKKDVPPSINTTNIDTLLVATDQTERIVEPP-ENIQEKIAFIFNNLSQSNMTQKVEELKETVKEEFMPWVSQYLVMKRVSIEPNFHSLYSNFLDTLKNPEFNKMVLNETYRNIKVLLTSDKAAANFSDRSLLKNLGHWLGMITLAKNKPILHTDLDVKSLLLEAYVKGQQELLYVVPFVAKVLESSIRSLVFRPPNPWTMAIMNVLAELHQEHDLKLNLKFEIEVLCKNLALDINELKPGNLLKDKDRLKNLDEQLSAPKKDVKQPEELPAITTTTTSTTPATSTTCTATV-------------------------------------------------PPQPQYSYHDINVYSLAGLAPHITLNPTIPLFQAHPQLKQCVRQAIERAVQELVHPVVDRSIKIAMTTCEQIVRKDFALDSEESRMRIAAHHMMRNLTAGMAMITCREPLLMSISTNLKNSFASALRTASPQQREMMDQAAAQLAQDNCELACCFIQKTAVEKAGPEMDKRLATEFELRKHARQEGRR---YCDPVVLTYQAERMPEQIRLKVGGVDPKQLAVYEEFARN----------------VPGFLPTNDLSQP------TGFLAQPMKQAWATDDVAQIYDKCITELEQHLHAIPPTLAMNPQAQALRSLLEVVVLSRNSRDAIAALG------------------------------------------LLQKAVEGLLDATSGADADLLLRYRECHLLVLKALQDGR----AYGSPWCN-----------------------------KQITRCLIECRDEYKYNVEAVELLIRNHLVNMQQYDLHLAQSMENGLNYMAVAFAMQLVKILLVDERSVAHITEADLFHTIETLMRINAHSRGNAPEGLPQLMEVVRS----------------NYEAMIDRAHGGPNFMMHSGISQASEYDDPPGLREKAEYLLREWVNLYHSAAAGRDSTKAFSAFVGQMHQQGILKTDDLITRFFRLCTEMCVEISYRAQAEQQHNPAANPTMIRAKCYHNLDAFVRLIALLVKHSGEATNTVTKINLLNKVLGIVVGVLLQDHDVRQSEFQQLPYHRIFIMLLLELNAPEHVLETINFQTLTAFCNTFHILRPTKAPGFVYAWLELISHRIFIARMLAHTPQQKGWPMYAQLLIDLFKYLAPFLRNVELTKPMQILYKGTLRVLLVLLHDFPEFLCDYHYGFCDVIPPNCIQLRNLILSAFPRNMRLPDPFTPNLKVDMLSEINIAPRILTNFTGVMPP-QFKKDLDSYLKTRSP-VTFLSDLRSNLQVSNE------PGNRYNLQLINALVLYVGTQAIAHIHNKGSTPSMSTITHSAHMDIFQNLAVDLDTEGRYLFLNAIANQLRYPNSHTHYFSCTMLYLFAEANTEAIQEQITRVLLERLIVNRPHPWGLLITFIELIKNPAFKFWNHEFVHCAPEIEKLFQSVAQCCMGQKQAQQVMEGTGAS-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A5YKK6-1", "uniprot_id": "CNOT1_HUMAN", "id": "A5YKK6-1", "name": "CCR4-NOT transcription complex subunit 1", "aln": "--------------------------------------------------------------------------------------MNLDSLSLALS-QISYLVDNLTKKNYRASQQEIQHIVNRHGPEADRHLLRCLFSHVDFSGD--------------------------------GKSSGKDFHQTQFLIQECALLITKPNFISTLSYAIDNPLHYQKSLKPAPHLFAQLSKVLKLSKVQEVIFGLALLNSSSSDLRGFAAQFIKQKLPDLLRSYIDADVSGNQEGGFQDIAIEVLHLLLSHLLFGQKGAFGVGQEQIDAFLKTLRRDFPQER------------------------CPVVLAPLLYPEK------------RDILMDRILPDSGGVAKTMMESSLADFMQEVGYGFCASIEECRNIIVQFG-VREVTAAQVARVLGMMAR---------------------------------------THSGLTDGIPLQSISAPGSGIWSDGKDKSDGAQAHTWNVEVLIDVLKELNPSLNFKEVTYELDHPGFQIRDSKGLHNVVYGIQRG-----LGMEVFPVDLIYR-PWKHAEGQLSFIQHSLINP-EIFCFADYPCHTVATDILKAPPEDDNREIATWKSLDLIESLLRLAEVG--QYEQVKQLFSFPIKHCPDMLVLALLQINTSWHTLRHELISTLMPIFLGNHPNSAIILHYAWHGQGQSPSIRQLIMHAMAEWYMRGEQYDQAKLSRILDVAQDLKALSMLLNGTPFAFVIDLAALASRREYLKLDKWLTDKIREHG-EPFIQACMTFLKRRCPSILGGLAPEKDQPKSAQLPPETLATMLACLQACAGSVSQELSETILTMVANCSNVMNKARQPPPGVMPKGRPPSASSLDAISPVQIDPLAGMTSLSIGGSAAPHTQSMQGFPPNLGSAFSTPQSPAKAFPPLSTPNQTTAFSGIGGLSSQLPVGGLGTGSLTGIGTGALGLPAVNNDPFVQRKLGTSGLNQPTFQQSKMKPSDLSQVWPEANQHFSKEIDDEANSYFQRIYNHPPHPTMSVDEVLEMLQRFKDSTIKREREVFNCMLRNLFEEYRFFPQYPDKELHITACLFGGIIEKGLVTYMALGLALRYVLEALRKPFGSKMYYFGIAALDRFKNRLKDYPQYCQHLASISHFMQFPHHLQEYIEYGQQSRDPPVKMQGSITTPGSIALAQAQAQAQVPAKAPLAGQVSTMVTTSTTTTVAKTVTVTRPTGVSFKKDVPPSINTTNIDTLLVATDQTERIVEPP-ENIQEKIAFIFNNLSQSNMTQKVEELKETVKEEFMPWVSQYLVMKRVSIEPNFHSLYSNFLDTLKNPEFNKMVLNETYRNIKVLLTSDKAAANFSDRSLLKNLGHWLGMITLAKNKPILHTDLDVKSLLLEAYVKGQQELLYVVPFVAKVLESSIRSVVFRPPNPWTMAIMNVLAELHQEHDLKLNLKFEIEVLCKNLALDINELKPGNLLKDKDRLKNLDEQLSAPKKDVKQPEELPPITTTTTSTTPATNTTCTATV-------------------------------------------------PPQPQYSYHDINVYSLAGLAPHITLNPTIPLFQAHPQLKQCVRQAIERAVQELVHPVVDRSIKIAMTTCEQIVRKDFALDSEESRMRIAAHHMMRNLTAGMAMITCREPLLMSISTNLKNSFASALRTASPQQREMMDQAAAQLAQDNCELACCFIQKTAVEKAGPEMDKRLATEFELRKHARQEGRR---YCDPVVLTYQAERMPEQIRLKVGGVDPKQLAVYEEFARN----------------VPGFLPTNDLSQP------TGFLAQPMKQAWATDDVAQIYDKCITELEQHLHAIPPTLAMNPQAQALRSLLEVVVLSRNSRDAIAALG------------------------------------------LLQKAVEGLLDATSGADADLLLRYRECHLLVLKALQDGR----AYGSPWCN-----------------------------KQITRCLIECRDEYKYNVEAVELLIRNHLVNMQQYDLHLAQSMENGLNYMAVAFAMQLVKILLVDERSVAHVTEADLFHTIETLMRINAHSRGNAPEGLPQLMEVVRS----------------NYEAMIDRAHGGPNFMMHSGISQASEYDDPPGLREKAEYLLREWVNLYHSAAAGRDSTKAFSAFVGQMHQQGILKTDDLITRFFRLCTEMCVEISYRAQAEQQHNPAANPTMIRAKCYHNLDAFVRLIALLVKHSGEATNTVTKINLLNKVLGIVVGVLLQDHDVRQSEFQQLPYHRIFIMLLLELNAPEHVLETINFQTLTAFCNTFHILRPTKAPGFVYAWLELISHRIFIARMLAHTPQQKGWPMYAQLLIDLFKYLAPFLRNVELTKPMQILYKGTLRVLLVLLHDFPEFLCDYHYGFCDVIPPNCIQLRNLILSAFPRNMRLPDPFTPNLKVDMLSEINIAPRILTNFTGVMPP-QFKKDLDSYLKTRSP-VTFLSDLRSNLQVSNE------PGNRYNLQLINALVLYVGTQAIAHIHNKGSTPSMSTITHSAHMDIFQNLAVDLDTEGRYLFLNAIANQLRYPNSHTHYFSCTMLYLFAEANTEAIQEQITRVLLERLIVNRPHPWGLLITFIELIKNPAFKFWNHEFVHCAPEIEKLFQSVAQCCMGQKQAQQVMEGTGAS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q75JL4-1", "uniprot_id": "Q75JL4_DICDI", "id": "Q75JL4-1", "name": "", "aln": "MSTKPSEIDLKKSSEVNNDSINNDNNNNSINNNDNNNNGNNKEETSEYTDPNNIFNKFNKLSSDKSFYKTWTLQVGSNNNNEQTDSNTISNLSFVIATQIKNLISNLTKKSYKSNSSELSQIINQYGSQAEIYIFRCLVDSIDFKNTNTPITTSPTTTSATSTTTSTPTTPSTTASSTAASSSSSNQLKIQLFKDEFSRLTKQPHFISVLCKAFDGYEVLNN------EFLVHFSSTLKLTPSHEIMLGLALSQSLDKEVREQADKFLLNTLIQLSQSNTKSLPENLLHQLLYKFKIQETNQLQQQNNQQQQNNQQQQQQQQQQQQQQQQQQQQQQQNSQQQQNQQHYSEVIKYLQSISPPNSLALSPLVDNDQSSGSGGGGITNSKRLQQDNPSYVNSIISKVSQQNVPYQIISSIGYSSCSSASTLKDILFQFQKLTESDIAQIIVSMAELTSNTNNNNNNNNENNDENEKTKIPYLTFNDLNDKETSNTSPTSSSPKQQSENESSSTTTTTNSNNNNNNNTTNIPDEWNISIFVDVIKELYPTIDWDIVIREMDCPIVNNMDQRGLAFILAVYKKATQVDQQQSKPFPIDFILDRVWVNSLSQIQFLKIAIQS--DFFPFQNSTKKRIDQSSLSKSTPP---TIAHWNSISLIETLLQLSDIDSEHYSKVKPLFDSPIKNCLDLLILGVSSITLKKNKLQNELLTTLFQTLLSQHNYQSIVSQLWKDHP-------LTVIQIMADITQK----DPKELSRLLDVAQELKILRQMLYCKTYPFIVNLAALASQREYLFLERWVQERMKEDDHQSFIKECISFLN--------DRVLKKGKSGEENSNTAASASPTTATTGSGSFPPQSIQISNNVLSTLCKTLMAAPDQIPTDLFNDLKNISAALQTAESETTERRFP----AEVEDETNSYFIKLYSGEISVDQIISVLKEYKVSKNQKDQDIFKCLLFNLFDEYKFLSDYPDKELKITGLLFGSLIKNQLISSQPLRVALKYVLEAMRFPLNSNMFIFGVNSLISFANRLVEWPQYWAQICSIDHFRDNYGDIILSVNKIIESSDPIKNGMEFQQQQQPQQQQQQQQPQQQPQQQKSANSPPATTILSSQQIQDAENFTYDSNTSSGNVGGGGNDISADQYHQLTPQQQQ----QLLQQQQMLQQQQLLQHKMAQQLQLQQQIQLQQQHHQHQQLQQ------------QQQQQHHQQHHHHQQQQQHHQQHQQQQQQQQQQQPNGKDDDKRKKDQEDAFSTTIPIGTLLNAS---KEMIQPD-DITKDKIYFIINNISQNNLDVKAKDLKDILKPEYYDYFAQYLVVKRVSIEANFHALYLAFIDRLCIPTISERVLFHSHQNVHTLLKSEKIRVDHSERSLLKNLGGWLGLNTLARNKPLLQKVISPKDLLIYAAENG--LLIAIVPFVAKLLEHCQQSKVFRPPNPWVMAILRLMVEIYQLKESKNNIKFEVELLCNNLSVDINTVKPTTILADRRQQREIEQQEENMRKDNKQS-------------------------------------------------------------------------------------SIDLLSNLPRYLVYTPSIGAYAQSPIFKKAVPLAFDKAVREIIAPVVERSVAIAVITSKELVSKDFATEADEQKMKRASHLMVQNLAGSLALVTCKDPLRVSIIAYLRTLLQNNN--GLPPCEIPLEHAISLVCNENLDFACSIVETAATEKAIISIDEVLASSYNDRLKHREQMGSQPFFDMGYLTTTIYNTLPESLRPKPGGIQPDQFRVYEDFTNLPHHINISNVGGAGETDNLTASPTNDIVSG------AIKSTGVMSQQLVQQQMQQQVSQQILQQQQQQQIQMQLLQQQAQQAALQAAQQQHQQQQQQQQQVQQQQQQVQQQQQQQQQNLPNSDLLEKF--------------GLLLNEVDKVVIRVLAQTQNIELELLYTISQQILTLVRMSQSQSELLAGFAQRLCNRLCEQEKKPIYEIYFELLEVLRDWDQKVITTITSFLLFSTPDKKLNRVLVAGLIIHQLININEYDLALSKMMIDSRSAPPIDFAISLLRFCLVENN---YANLSEFPSTFDLLQKISSRS---PSEMLAKTLEEIKN----------------SPKEEKKRRISR--------IRQEDMIVDPPGLREAVIALLQDWLLFSSTNTD----QKILIQYLGQVLQISFMKNELYFIKFFRLGLEYALER------------YAANVEIQSPQYLEIDSWCRFVVMMVKHA-----DPTKLNMLTKVLSVLIKILTKDYENNPSRFNQRPYLRIFENLLVDLTSPDPILEHVSNHILFCFVNALATLQPQKYPGFCFAWLDLLSHKSFMPKLLIRQQKQ----WFHALLVQHFKFLEPFLRGGDLSEPVRVLYKGTLKVLLLLLHDFPEFLCEYHFSLCDVIPNTCIQLRNLILSAFPRNMRLPDPFTPNLKIDMLPDINQPPKISSNFTASLK--GLKIEIDNYFKNRGP-YSFLLDLKNKHLLLTDKEEILAAGTKYNVPLINSLVLYIGTLAIPQIQRK--SGVAPTPSQSAPMDIFHRLALDLDSEGRYIFFNAIANQLRYPNNHTHYLSCVILFLFSESGQDIIKEQITRVLLERLISNKPHPWGLLITFIELIKNLRYNFWSHGFTKVAPEIAQLFDSVAKSCLNRESSNLSQ-----------", "tax_id": 44689, "tax_name": "Social amoeba" }, { "uniprot_ac": "F4HVV7-1", "uniprot_id": "F4HVV7_ARATH", "id": "F4HVV7-1", "name": "", "aln": "------------------------------------------------------------------------------------------MTPSKVAGHTRFLLHSFHDSDVDSIALQLSQFVD-FGVETSIPVLKTCLDCFTARRS-----------------------------------HPNSLQLEKVVSLLFKHVLKLSNLATLLPHALNDFELTQES-------VDDLTTTLNFSISENIGFALALTDFERLDAKTTGRNLLLAQIEQLCANTGQILSSELIHSVLSFLRKSEDLSMHLDSFLQFLSSAQPRDDFSFALTPMLAQQVHEAP--------------------------VFRSMDFHTDS------------------ADNDLDAILAEIDKEVSVGDLMGELGCGFTADAQQCKEILSSFAPLGEATISRIVGNVSRTCA----------------------------------------------DLEDNQTTFSTFTVALGSCIPTELPTPRSWNVDILVDTIKQLAPGISWRKVIENLDHDGFDIPNMESFSFFMRIYKAA------CKEPFPLDAVCGSVWKNMDGQLSFLKHAISAPPEVFTFMHSPRKLVYIDNMHSQEQQLGLSNHAWLSLDLLDVLCQLAERG--HAVLVSSLLQYPLTQCPRTLLLGMTHIKTAYNLIQREVVSAILPVIITSPQDSGFIHNLWHQNAELVLWGIIDAQHLKADSMLR-----------IIEICHELKILSVVLESVPVSSSIRLAVLASLRGLLDIENWLPNCLYMYK-DLFAEECLKFVKN-----------------VHFSESDDFRAKIFHPSDPLSDLHLEATTSLLKVLKAHDNAITSSQLVEEIEKVNAAILDCNPKLQNGEAKDSSAPNAYGDDVEAEANAYFHQMFSSHLSVDAMVQMLSRYKESLVPREKLIFECMIANLFEEYRFFPKYPERQLKIASILFGSVIKHQLISSLTLGMALRLVLDSLRKPADSKMFLFGSKALEQFVNRLVELPQYCNHILQISHLRSTHPELVTVIEQALSRIS-----------------SGNLESDASVSHPGPSQSFPGNGELSGSGIG------------------------------------------------------------QPALQLSSPLQLQQKNEVPSVPSN----------------EAKPLLPSLSTTSVDVSVNPKNPGIPTSSSTSTGFVRPARATTSTRFGSALNIETLVAAAERRENAIEAPPSDVQDKVSFIINNISTTNIESKGKEFAEILPQQYYPWFAQYMVMKRASIEPNFHDLYLKFLDKVDSKLLFKEILQNTYENCKVLLGSELIKSSSEERSLLKNLGSWLGRLTIGRNYVLRAREIDPKSLIVEAYEKG--LMIAVIPFTSKVLEPCQNSIAYQPPNPWTMAILGLLAEIYSMPNLKMNLKFDIEVLFKNLGVEMKEVVPTSLLKDRKREIDGNPDFSNKDPGVTQISQPQMIPEPKTISPLKQIDLPLDVANSPNTDVPSKLLSQYVAPQRVYTNTLMDEEKVATLGLPEQLPSPQGLFQSTPSPLFSISQLSAALPNIGNHVVINQKLSAFGMHFPFQRVVPLAMDRAIKEIVSGIVQRSVCIACQTTKELVLKDYALEPDESRIYNAAHLMVASLAGSLAHVTCKEPLRTSISGHLRNSLQGLN-----ISNDALEQIVQLVTNDNLDLGCAAIEQAATEKAIQTIDADIAQQLLLRRKHRDGAGS-SFFDPNILSQNSVSFIPESLRPKPGHLSLSQQRVYEDFVQHPWQKQSTQTSHG---LSAASSSSGDVALGSGYGPVSGKVASEFLSNAGNARMDMVSRPSDISVDGFESSPVSLLSSQVDPAGDSSSLQFTKSLPTSELNLAESSDAATKETGTSLQTLTSAATMERLGASNITQPSLSTRDALDKCQIVTQKMEELVANNAGDDEIQAVISEVPEIILRCISRDEAAFAVAQKAFKALYENASSNLHVSANLAILVAIRDVCKRVVKELTSWVIYSEEDRKLNKDITIGLIQRELLSLAEYNVHMAKHLDGGRNKTATDFAISLLQSLVTEES----SVISELHSLVDALAKLASKS--GSSESLQQLIDIIRNPVTNTAGLSDSSTGNDNNDRQKDEKVACNTTNTEESTSLDYVESDPAGFQNRVSTLFKNWYQICELPGAN---ETACSQYVLHLHQTGLLKGDDTTESFFRILLELSVAHCISSE-DINSGAVQSPQQPQSPSFLIIDMYAKLVFSILKYFPE-QESSSRLFLLSEIMADTVRFIQKDAEDKKTSLNSKPYFRLFINWLLDLCSLDPGTDGANFQVLTAFANAFHALQPLKIPAFSFAWLELVSHRSFMPKLLT-VNGQKGWPYVQRLLVDLLQFLEPFLRNAELGGPVHFLYKGTLRVLLVLLHDFPEFLCDYHFTFCDVIPSSCIQMRNIILSSFPRNMRLPDPSTPNLKIDLLPEIVEAPCILSEVDAALKAKQMKNDVDEYLTSRQQNSTFLSELKTKLLLSSS--EASSAGTRYSVPLINSLVLYTGMQAIQQLQAG-----ETQAQNVVALQMFKYLSMELDTEGRYLFLNAIANQLRYPNNHTHYFSFIMLYLFFESDQEIIQEQITRVLLERLIVNRPHPWGLLITFIELIKNPRYSFWKQAFIRCAPEIEKLFESVARSCGGLKPVDEGMVSGGWVSDNSH", "tax_id": 3702, "tax_name": "Mouse-ear cress" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: : *: .: ... : ::.:::: .* ::. ::: .. . .. :.. : . .:: : * *::. :: . .::..*::: .:: :.*** : : : . ::: : :* . . . . : : . : . . :: :: : : : . :. .. ::: : ::: .:* . :. . ::*: .* : * ::: :. :. : . .. . . **:.:::*.:*:* * :.: * ::* .: : ..: .: : . : **:* : * : .*:.*:: :: :.* * . . : : . : * *:.*:: * :*:: . : *. *:. *:.:* *:*.: *. : ::.*:::::: :: . ..:: : . : *: : ::::.::** * :* . . : **.*** * * ::.*: : : : * : *:.*:: . : . . : : .. : . . .. . . . .: .: .: .: . .:. .. . : . : .: :. .::.: *:: : .. : * :*:* . . : .*: .. :.:: . . ::: :. . : : . :. . * . * :*.. :: *: . : : : . . . . .: * **: *: :. ::. . ::*: **:**:* .*: * ::: : : :: :.:**:*:**.***.*** ** *:* : : : :* .::.* :.** *: . .:******** *** *:.:* : :. *.*:: * :* :: ::**.:*:** . .* .::*****.***: ::.*::. : * *:**::*:* :**.:::: : * .:* *: : : : : . . .* *..: ::. . .: : ::: * *:::*::*:: :*:**: ** * :::* **:* :.:*.:: *:* *: .*:..:* :**::** ** *:. : . . ::: : ::* ::.*. :: :*.*** :* :* . * : *: : : . :**.:* * * :. .* ***:*.. .:.*: : : : . : . : * : : . : : .. : : . * .. : :: : ::: . . . :* :: . : * * . ** ..*:.: :*:: ::: : .. . . **:.*:: :.:: ::: .: * :: ::* ..* * : :: ::. . . .. . **.*::: . *:::* : . :: :: * .::* : ***: * .: :: : :* : ::: ::*: ::: :*.:::. : .: :* : . : ::. ** *:* *::* : : : . : * .* *:: *:* * *.* :***:*:**: *:.::* * **:: :::* ****. :* *::.******:***:**********:**: :***** .***:**:***:********** *****:*:*.:* .* * ::. . : :* ::*.*:..* :** :*:.: : .. .*.:*.: ***:**** * ** ::: . : . :::*: *:::**:****:*:***********.****:* :*:** *:. : *:************ *:**************** :.**.: * : **** :**:***:.* . : : ", "identical_positions": 400, "similar_positions": 739, "identity": "14.49%" }, { "cls_id": "homologset.oma.834050", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P25655-1", "uniprot_id": "NOT1_YEAST", "id": "P25655-1", "name": "General negative regulator of transcription subunit 1", "aln": "----MLSATYRDLNTASNLETSKEKQAAQIVIAQISLLFTTLNNDNFESVEREIRHILDRS-----SVDIYIKVWERLLTLSSRDILQAGKFLLQENLLHRLLLEFAKDLPKKSTDLIELLKERTFNN-----QEFQKQTGITLSLFIDLFDKSAN----------KDIIESLDRSSQINDFKTIKMNHTNYLRNFFLQTTPETLESNLRDLL--------------------------------------------------HSLEGESLNDLLALLLSEILSPGSQNLQNDPTRSWLTPPMVLDATN-----RGNVIARSISSLQANQINWNRVFNLMSTKYFLSAPLMPTTASLSCLFAALHDGPVIDEFFSCDWKVIFKLDLAIQLHKWSVQNGCFDLLNAEGTRKVSETIPNTKQSLLYLLSIAS----------------------LNLELFLQREELSDGPMLAYFQECFFEDFN------------------------------------------------------------------------------YAPEYLILALVKEMKRFVLLIENRT---------------------------VIDEILITLLIQVHNKSPSSFKDVISTITDDSKIVDAAKIIINS-------------------------------DDAPIANFLKSLLDTGRLDTVINKLPFN----EAFKILPCARQIGWEGFDTFLKTKVSPSNVDVVLES---------------------------------------------------------------LEVQTKMTDTNTPFRSLKTFDLFAFHSLIEVLNKCPLDVLQLQRFESLEFSLLIAFPRLINFG------------------FGHDEAILANGDIAGINNDIEKEMQNYLQKMYSG----ELAIKDVIELLRRLRDSDLPRDQEVFTCITHAVIAESTFFQDYPLDALATTSVLFGSMILFQLLRGFVLD-VAFRIIMRFAKEPPESKMFKFAVQAIYAFRIRLAEYPQYCKDLLRDVPALKSQAQVYQSIVEAATLANAPKER--------------SRPVQEMIPLKFFAVDEVSCQINQEG------------------------------------APKDVVEKVLFVLNNVTLANLNNKVDELKKSLTPNYFSWFSTYLVTQRAKTEPNYHDLYSKVIVAMGSGLLHQFMVNVTLRQLFVLLSTKD--EQAIDKKHLKNLASWLGCITLALNKPIKHKNIAFREMLIEAYKENR--LEIVVPFVTKILQRASESKIFKPPNPWTVGILKLLIELNEKANWKLSLTFEVEVLLKSFNLTTKSLKPSNFINTPEVIETLSGALGSITLEQQQTEQQRQIILMQQHQQQMLIYQQRQQQQQQRQQQ---QQHHISANTIADQQAAFGGEGSISHDNPFNNLLG------------------------------------STIFVTHPDLKRVFQMALAKSVREILLEVVEKSSGIAVVTTTKIILKDFATEVDESKLKTAAIIMVRHLAQSLARATSIEPLKEGIRSTMQSLAPNLMSLSSSPAEELDTAIN---ENIGIALVLIEKASMDKSTQDLADQLMQAIAIRRYHKERRADQPFITQNTNPYSLS-LPEPLGLKNTGVTPQQFRVYEEFGKNIPNLDVIPFAGLPAHAPP----MTQNVGLTQPQQQQAQMPTQILTSEQIRAQQQQQQLQKSRLNQPSQSAQPPGVNVPNPQGGIAAVQSDLEQNQRVLVHLMD-ILVSQIKENATKNNLAELGDQNQIKTIIFQILTFIAKSAQKDQLALKVSQAVVNSLFATS-----ESPLCREVLSLLLEKLCSLSLVARKDVVWWLVYALDSRKFN--VPVIRSLLEVNLIDATELDNVLVTAMKNKMENSTEFAMKLIQNTVLSDDPILMRMDFIKTLEHLASSEDENVKKFIKEFEDTKIMPVRKGTKTTRTEKLYLVFTEWVKLLQRVENNDVITTVFIKQLVEKGVISDTDNLLTFVKSSLELSVSSFKESDPTDEVFIAIDALGSLIIKLLILQGFKDD--TRRDYINAIFSVIVLVFAKDHSQEGTTFNERPYFRLFSNILYEWATIRTHNFVRISDSSTRQELIEFDSVFYNTFSGYLHALQPFAFPGFSFAWVTLLSHRMLLP-IMLRLPNKIGWEKLMLLIIDLFKFLDQYTSKHAVSDAVSVVYKGTLRVILGISNDMPSFLIENHYELMNNLPPTYFQLKNVILSAIPKNMTVPNPYDVDLNMEDIPACKELPEVFFDPVIDLH--SLKKPVDNYLRIPSNSLLRTILSAIYKDTYDIKKGVGYDFLSVDSKLIRAIVLHVGIEAGIEYKRTSSNAVFNTKSSYYTLLFNLIQNGSIEMKYQIILSIVEQLRYPNIHTYWFSFVLMNMFKSDEWNDQKLEVQEIILRNFLKRIIVNKPHTWGVSVFFTQLINNNDINLLDLPFVQSVPEIKLILQQLVKYSKKYTTSEQDDQSATINRRQTPLQSNA", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A0B4LEZ3-1", "uniprot_id": "A0A0B4LEZ3_DROME", "id": "A0A0B4LEZ3-1", "name": "", "aln": "MCPRLRAVAVKALILASKPYAMQLFDSKPYITDSIYDILQFVKEHGLEADRSSLRHLFSVINFSDLVPSVTVQLQAKLLGIQLERQLHSSSFVSNICYAFDQFFASNQKQSLKPVAVADLVGQVARLTGINKVCECVFALALTHSSYTELKHSARNNLKGSLSELIDSYLGNKGTGPADSGLREISFDLLQYLLCCLSEYVQPQVEAQFLIKLREEFPRQAVPLVLAPFLYGSTTATIAGAGASETDAEAEATTNSNSSSFEADALNEVGIEDIYDHLSEIIFTNQGKNNIMDTSWINLILEIGYEFTSSVEECKNHLCSRERERAELQSKDVAKIVGLMCRRHSSLLDCNVNLPTPANFWPGQGQGGGSNSSGSSQTQITPQQQNPGSSNNNDGSDGNSSSDKKDKKETTEATQTWKPDVFVQALKEVVPQLNWKDVCMELDHPEFVLKDRIGLELLLTILRLATGSNIFPHPECIYRHWANTEGQLSLIATMLKNPDLFSFADFVFSQPALDVLKTAPDADNKEISSWKSLHLVEVLLSIADKGYYTQVHELFKFPAQNCPDVLFLALLNTSPPMTPLRQDLFNQLIPTFLGNHPNSNVILASAWSSNNFQLRSNIMNAMSEWYLRGNEFDQVKLSRILDLAQDLKALSALLNARSFLFIIDLACLASRREYLKLEKWLTDKIREHGEPFMQAIIKVLHRRCPQVINAKVPEDQLPPKQAQLLPETVTTMINCLQTCINNCMQPEMVEVIMQMTANVAIMANKARAQQQQQPGLVPPPPPTILRGHRGMDLPGGIVPPPPQQPFSGNLNAQMFGPGMDPLTNMSNNLAGLNLSGPNGAFNFGNMLTSPSRLMTPGANPYPLNLMQMPQAPPPPNVGNLGRMLPGGPQQQTPTPTPTAPNPNNPVMADLQIP-VSKEVEDEVNSYFQRIYNHQPNPTLSIDEVLDILQRFKESSNRREQEVFLCMLRNLFEEYRFFCQYPEKELQITAQLFGGIIDRNLVPTFVALGLSLRCVLDALRKPDGSKLYYFGVTALDRFRTRLHTYNKYCEHIR-SIPHFSDFPPHLIQYVEYGMHGQEPPPQKLIGLSNTIPSAISSGPGTEPIYRNSSMLGNMPAATPGSGPKSNAAVSHATRMKSIANATNIDTLLVANQEEKVTVPPEPVQDKTAFIFNNLSQLNIPQKCDEIKEIMTKEYWPWLAQYLVLKRASMEFNFHTLYYNFLDALKNGEINRFVTKETLRNIKVLLRSDKGVINFSDRSLLKNLGHWLGMMTLGRNRPILQLDLDLKSLLAEAYHKGQQELLFVVPFVAKILESSAKSRIFRSPNPWTMGIMYVLAELHQEPDLKLNLKFEIEVLCKTLNLELAKLRQVIYLKDPNRTHRIEEQMSQPKPKQLEPVASAPALPREQQSPAQPPPPPQQQQPPQQQVPPPPSSADVDAQNAAAMMMAAGGANSTPGSVSSPNLPTDSSQVALPPPEPRYSYVDVNVSNFQLIGQQLVLPPNTPFLHANPGIKHMVVNAVERTITDWLQPIVDRSIRIACATTEQIIRKDFALDADENRMRTAAHQMVRNLAAGMAMITGKDEIARAISQNLHKALLSGLNGMPSMAEIQAAAMQLASENVELVCAFIQKTSAEKAAAEIDRRLSTDFETRKIAREE--GNRFVDAQILTYQQERLPEAVRIKVGAAPATLYAVYSEFARSIPGFQQMSDRDIALFVPKPTDLSQPNVFANDDSMVYGELASKMEAFMNTAIGVPTLQIQASKMHMLLN-ALIATRRLRDQESAFNLLTRAVEGLTEGLVNMHENMEQMKMYQNIHLRILGLLNNSFGAPNTERAVTKCFFDIREEVRYNVEAARALITSHFVNLNQFDGMLRDCMDNGNNYVAISFGIALLERLIMDDRVINIVSDNEFMATVELLGRLTQHRHRYPECIVNAIDTLWSGNFNSSSDYSPFNGNDRYLSGASHYIHSGMHHVRSCDTDDPPGLQEKTEFLLKDWVALYTQQNQQSTRDARNFGAFVQKMNTYGILKTDDLITRFFR----QATHICTDVVYRMFAEPSLPINQAKN-------KIFQWIDAFVHLIAMLVRHSGEAGNPTTKINLLNKVLGIVLGTLIKDHEMRGVSFQQVGYHRFFMMLFMELCTADVILESLMHS-------------IVSAFAYTYHLLNPSVAPGFCFAWLELISHRVFLGRILVQIPGQKGWPLYAQLLQDLFKYLAPFLRNTELGKPVQLLYKGTLRVLLVLLHDFPEFLCDYHFGFCDTIPPNCVQMRNIILSAFPRNMRLPDPFTPNLKVDMLSDSSNAPKVLSSYIMNIQPANFKKDLDSYLKARAPVTFLSELRGHLQVTS--EPGTRYNMALMNALVMYVGTQAIALIRNKNFVPNTSNIAH---SAHMDIFQNLAVDLDTEGRYLFLNAIANQLRYPNSHTHYFSCAVLHLFAEANS----EAIQEQITRVLLERLIVNRPHPWGLLITFIELIKNPIYKFWDHDFVHCAPEITKLFESVARSCLAKSNVTQQLNMPVVDGEGQEVATIN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.: : * **: : : :: : .* :: :::..:*: . .:**::. .: ::: :** :. . *::..*: : . :: :. . *.. : :*: : : . * .:* * : :* ..: * .. : . . .. ..:: *.:: :** : : . :*::: * .:*: .::*: * . *:: .:* *.: * : : *. :.:: :*. . : :. : ::..**. :: . .: : ::.. :* :. *.: :: : : . . :: . .:* . : : ..... * . . : :: *. . :.***:* .*: *. : . **::..: .*: *:***:: :. * :: : . ::. : : : :. . : :* * * :: :.* . ::*: .. *: : : .:*. :.: *:* : : ::** : : ::* ::. :.*. *:*::: :: *:*::. : :. . . * * .:: .: : :: :::. . *.: *:* . ::.::*: :*. :.:::*.*::.*:*::*. *:*.:*:::*:*:::*. *:**** *: : :: * ** :** . * *: ***.:* :*: ** :::* :: ::* **:: *.* *: ** ** * :**:.: .:* :.. . . ** . .: * : * * * * : :.::.. .* .*: * :*. *::**:: *: :* **:*: :* :*:.*:: *** :**. * *:* ** :.: *: .* :::*:.: ***:: *** :.. : *:. ****. *** :**. *:** : :: ::.:* ***::.: * :*****:***: :::*:**:.*****:**: :* **:::.: **.*.**:*** *::** .*: ::: *: . :. :.. . :* :. . : :*:. :*** *:* .. .:.*:. * * ** .* . . . ** :.:: ::*.:*::. *: ::: : * :*::* ** .** :** **** :.**.:::*** ***:** .:* *. : : ..* ..::. . :. .* ** :*:: **: :. .:*:*:* :*:: :: :* : *: :*. .: *: : .*. . ***.: :* .... : **.**.:.**.:: :. .:. ..* ** .: . .::.::: : : *:* *::: : * . .: : :..: : :* . **:: : : :: :* . *. *.:. . : . : . :: : ::.::*::.* *.. * : . : .::*: * : :: :...:* * :: * : . . : *.: * ..:::.*:::: :: **. . :: .: :. . :.. :* ::* : .::. ::** : : .*.: :: ::.:*:** .* : *. *.:.** :. :. ::* ***: ** *: .* .: *: : :* ::.::: .: ***. .*.:*:: *.*:* :: * .* . : . : .:*: * *:* . ***.***: *:***::* *::::*.: ** *: ****:* : : :...*.::*******:* : :*:*.** : *: : :.:**. .*::*:****:*:** :*:*: :*::: :. ..: *:*: . ::::: .:** :*.**: : : : * . : * : *. *:: ::: :: . . :.: . :: .:** .. *:: :: ** : . * :* :: :*.:****** **::** .::::* . : :** * * :*:*:***:**.**: : * :**:* :: * **:..***. :::.:.: . :. *: : ..:: . : : ", "identical_positions": 452, "similar_positions": 864, "identity": "17.73%" }, { "cls_id": "homologset.oma.834099", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L225-1", "uniprot_id": "A0ABK0L225_RAT", "id": "A0ABK0L225-1", "name": "DNA/RNA-binding protein KIN17", "aln": "MGKSDFLSPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIEEQVR--------RGLEGKEQE-TPVFTELSRE---NDEEKVTFNLNKGAGSSAGATTSKSSSLGPSALKMLGSTASVRRKES----SQSSAQP-AKKKKKSALDEIMEIEEEKK----------------------------------------------------RTARTDSWLQPGIIVKIITKKLGEK-YHKKKGVVKEVIDRYTAVVKMTDSGDRLKLDQTHLETVIPAPGKRVLVLNGGYRGNEGTLESINEKTFSATIVIETGPLKGRRLEEPRTEPRTLHLLGKRTTAELNPQPKTSIF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K339-1", "uniprot_id": "KIN17_MOUSE", "id": "Q8K339-1", "name": "DNA/RNA-binding protein KIN17", "aln": "MGKSDFLSPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIEEQVR--------RGLEGKEQE-TPVFTELSRE---NEEEKVTFNLNKGAGGSAGATTSKSSSLGPSALKLLGSAASGKRKES----SQSSAQP-AKKKK-SALDEIMELEEEKK----------------------------------------------------RTARTDAWLQPGIVVKIITKKLGEK-YHKKKGVVKEVIDRYTAVVKMTDSGDRLKLDQTHLETVIPAPGKRVLVLNGGYRGNEGTLESINEKAFSATIVIETGPLKGRRVEG----------IQYEDISKLA--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3GR62-1", "uniprot_id": "G3GR62_CRIGR", "id": "G3GR62-1", "name": "DNA/RNA-binding protein KIN17", "aln": "MGKSDFLSPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIEEQVR--------RGLEGKEQE-TPVFTELSRE---NDEEKVTFNLNKGAGSSAVATSSKSGSLGPSALKTLGSASSMRRKES----SQSSAQP-AKKKKKSALDEIMELEEEKK----------------------------------------------------RTARTDSWLQPGIIVKIITKKLGEK-YHKKKGVVKEVIDRYTAVVKMIDSGDRLKLDQTHLETVIPAPGKRILVLNGGYRGNEGTLESINEKTFSATIVIETGPLKGRRVEG----------IQYEDISKLA--------", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "O60870-1", "uniprot_id": "KIN17_HUMAN", "id": "O60870-1", "name": "DNA/RNA-binding protein KIN17", "aln": "MGKSDFLTPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIEEQVR--------RGLEGKEQE-VPTFTELSRE---NDEEKVTFNLSKGACSSSGATSSKSSTLGPSALKTIGSSASVKRKES----SQSSTQSKEKKKKKSALDEIMEIEEEKK----------------------------------------------------RTARTDYWLQPEIIVKIITKKLGEK-YHKKKAIVKEVIDKYTAVVKMIDSGDKLKLDQTHLETVIPAPGKRILVLNGGYRGNEGTLESINEKTFSATIVIETGPLKGRRVEG----------IQYEDISKLA--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A4X1TC89-1", "uniprot_id": "A0A4X1TC89_PIG", "id": "A0A4X1TC89-1", "name": "DNA/RNA-binding protein KIN17", "aln": "MGKSDFLTPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIQEQVR--------RGLEGKEQE-APIFTELSRE---NEEEKVTFNLNKGACSS-AAASSKSSSLGPSALKTMGSTASVKRKES----SQSSAQSKEKKKKKSALDEIMEIEEEKK----------------------------------------------------RTARTDHWLQPEIIVKIITKKLGEK-YHKKKGVVKEVIDKYTAVVKMIDSGDKLKLDQTHLETVIPAPGKRILVLNGGYRGNVGTLESINEKTFSATVVIETGPLKGRRVEG----------IQYEDISKLA--------", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A8V0XK22-1", "uniprot_id": "A0A8V0XK22_CHICK", "id": "A0A8V0XK22-1", "name": "DNA/RNA-binding protein KIN17", "aln": "MGKSDFLSPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFLNYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQQEQERKKKQDLDDEEKTAKFIEQQVR--------RGLEGKELE-EPVYTELNRE---NEEEKVAFNLNKGASTSVAASSKTSSILGPSALKMA--EGAVKRKES----AHSSGQS-KEKKKKSALDEIMELEEEKK----------------------------------------------------RTSRTDYWLQPEIIVKIVTKKLGEK-YHKKKAVVKEVIDKYTAVVKMIDSGDKLKLDQTHLETVIPAPGKKVMVLNGGYRGNEGILESINEKKFSATIIIDSGPLKGRRVEG----------IQYEDISKLA--------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q9VPH4-1", "uniprot_id": "Q9VPH4_DROME", "id": "Q9VPH4-1", "name": "", "aln": "MGRAEVGTPKYLANKMKSKGLQKLRWYCQMCEKQCRDENGFKCHTMSESHQRQLLLFADNPGKFLHSFSKEFSDGYMELLRRRFGTKRTSANKIYQEYIAHKEHIHMNATRWLTLSDYVKWLGRTGQVIADETEKGWFVTYIDRSPEAMERQAKADRKEKMEKDDEERMADFIEQQIKNA------KAKDGEEDEGQEKFTELKREE--NEPLKLDIRLEK--------KFQPDTVLGKSALAKRPAPEAEEKVFK----KPKSVAG--DSQTRSVLDEIIKQEESKKE---------------------------------------------------RANRKDYWLHKGIVVKFISKSMGEK-FFKQKAVVLDVIDRYQGKIKFLETGEKLKVDQAHLETVIPALDKPVMVVNGAYRGSEALLRKLDERRYSVSVEILHGPLKGRIVDN----------VQYEDISKLHGA------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9ZVU5-1", "uniprot_id": "KIN17_ARATH", "id": "Q9ZVU5-1", "name": "KIN17-like protein", "aln": "MGKNDFLTPKAIANRIKAKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQMQVFGQNPTRVVDGYSEEFEQTFLDLMRRSHRFSRIAATVVYNEYINDRHHVHMNSTEWATLTEFIKHLGKTGKCKVEETPKGWFITYIDRDSETLFKERLKNKRVKSDLAEEEKQEREIQRQIERAAEKLNGGGGEGETSGNDEVVDDGDDERKKDEDLRLKSGVKVGFALGGGVKQVATGKERGESSKLLFGDEENDKVERGEKRKRSGDSGRSEKERRSALDELMKEEEKKKE---------------------------------------------------RMNRKDYWLFEGIIVKVMSKALAEKGYYKQKGVVKKVIDNYVGEIKMLDSKHVLRVDQKELETVLPQIGGMVKIVNGAYRGSNARLLGVDTEKFCAKVQIEKGVYDGRVIKS----------IEYEDICKLA--------", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q55D16-1", "uniprot_id": "KIN17_DICDI", "id": "Q55D16-1", "name": "KIN17-like protein", "aln": "MGKGDALTPKQIANKIKAKGLQRLRWYCQLCEKQCRDENGFKCHISSESHMRQMEVFSNKSSFIVSQYSKEFEEDFLRIMSRQFINSRVPANQVYAEYIKDRHHIHMNATEWTSLTEFVKYLGKTSKCEVEETPKGWFIRYINRDPEYVMRKVSEEKKEKAELNEEERQRLQIEKQIK--------ELNKNKIEQDEIKPTELSKED-LEKMSLLELNIKSTTNTTTTTTNTTTTTTNKNIFDKLKTNDNNSSNNN----YNDQTNPKPYAKKMSAIEEIMFKEKEKERQQKEKLEFEKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLNSNNNNNEEKPWIIKDIVIKIIDKELANGKYFKQKGYIVSVENEFLAKVKLLDSGDILKIDQTFLETVIPQIGSTVIIVNGKYRGKEATIKNVNFDDFNAKLYIKDNDITIT--------------LPYESFSKQY--------", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: : :** :**::*:****:******:*:************ **** **: : .::. .: :*:** : :: :: * . .* . :* *** .:.*:***:*.* :*::: * **: . .:** ***:: **:*..* : :: ::: * : :**: *:.*:. ..: : . * :. : :. . . : *.::*:: *:.*: . . . *: *::*.: * :.: :.*:*. : .* :.: . :*: :: . *::** ****:* . : ::** ***. . : :: : ..: * . : . .: ", "identical_positions": 96, "similar_positions": 129, "identity": "20.0%" }, { "cls_id": "homologset.oma.834125", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A2I6-1", "uniprot_id": "A0A8I6A2I6_RAT", "id": "A0A8I6A2I6-1", "name": "Ferric reductase 1", "aln": "--------------------------------------------------------------------MAAPQFTLSVLVCALLICSVTAYPNGRVARSCAGMIPQHNHSPQSDPVHKITVSQMKFKPGDQIKVTLSGPPFRGFLLEARNAEDLSGPPIGTFTLIDSDSSQILTCEDVQGFAVSHTSSSIKTEIKVYWNAPSSAPDHVQFLATVVQKYKIYWVKIPGPVISQPSAPPFTTPEATT-QPLTMAPSVSHLTKPFSASECGNKKFCVRSPLNCDPENEPACVFLSFTRENQSVMVEMSGPSDGYVSFAFSHDQWMGDDDAYLCIYEDQTVYIQPSYLTGRSYPVMDSRGTLEDMAWRLADGVIQCSFRRNITLPEAKNRFVLNESYYIFYAEGAAHDGR-IFRHSQQPLITYEKYNVTGTPQNVGGSRSSALLKAHGALMFVAWVTTVSTGVLVARFFRSVWSKAFFFGQAAWFQVASMFRVCVCVCVCVCVLLCFPYRMGGSFRAGYHPYLGCIVMTLAVLQPLLATFRPPLHDPRRQVFNWTHWSVGTAARIIAVAAMFLGMDLPGLDLPSPQKTYAMMGFVVWHIGTEVILEIHAYLLSRKVEILDDDRIQILQSLTVAEAEGHVFKKVVLAVYICGNVTFLMIFLSAISHV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K385-1", "uniprot_id": "FRRS1_MOUSE", "id": "Q8K385-1", "name": "Ferric reductase 1", "aln": "--------------------------------------------------------------------MAAPQITLSVLVIALLTCSVTAYPNGKVPMSCGGMIPQHNHSPQSEPIHQITVSQTTFKPGDQIEVTLSGPPFRGFLLEARDAENLSGPPIGSFTLIDSEESQLLTCTDVQGLAVSHTRSSKKTEIKVYWDAPSPAPDHIRFLATVVQKFKIYWVKIPSPVISQPNAPPFTTPKATT-QPLTTPPSVSHLTKPFSAFECGNKKFCVRSPLNCDPEKEPACVFLSFTRDNQSVMVEMSGPSDGYVSFAFSHDQWMGDDDAYLCIREDQTVDIQPSYLTGRSYPVMDSRGTLEDMAWRLADGVIQCSFRRNITLPEAKNRFVLNESYYIFFAEGPSHDGR-IFRHSQQPLITYEKYNVTDTPKSVGGSRSSPLLKAHGALMFVAWMTTVSIGVLVARFFRSVWSKAFFLREAAWFQVHRMLMVATSLLTCVAFVLPFVYRGGWSWRAGYHPYLGCTVMTLAVLQPLLATFRPPLHDPRRQVFNWTHWSVGTAARIIAVAAMFLGMDLPGLNLPSPQKTYAMMGFVVWHIGTEVILEIHAYRLSRKVEILDNDRIQILQSLTVAEAEGHVFKKVVLAVYICGNVIFLSIFLSAINHI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZNA5-1", "uniprot_id": "FRRS1_HUMAN", "id": "Q6ZNA5-1", "name": "Ferric reductase 1", "aln": "--------------------------------------------------------------------MAVSGFTLGTCILLLHISYVANYPNGKVTQSCHGMIPEHGHSPQSVPVHDIYVSQMTFRPGDQIEVTLSGHPFKGFLLEARNAEDLNGPPIGSFTLIDSEVSQLLTCEDIQGSAVSHRSASKKTEIKVYWNAPSSAPNHTQFLVTVVEKYKIYWVKIPGPIISQPNAFPFTTPKATV-VPLPTLPPVSHLTKPFSASDCGNKKFCIRSPLNCDPEKEASCVFLSFTRDDQSVMVEMSGPSKGYLSFALSHDQWMGDDDAYLCIHEDQTVYIQPSHLTGRSHPVMDSRDTLEDMAWRLADGVMQCSFRRNITLPGVKNRFDLNTSYYIFLADGAANDGR-IYKHSQQPLITYEKYDVTDSPKNIGGSHSVLLLKVHGALMFVAWMTTVSIGVLVARFFKPVWSKAFLLGEAAWFQVHRMLMFTTTVLTCIAFVMPFIYRGGWSRHAGYHPYLGCIVMTLAVLQPLLAVFRPPLHDPRRQMFNWTHWSMGTAARIIAVAAMFLGMDLPGLNLPDSWKTYAMTGFVAWHVGTEVVLEVHAYRLSRKVEILDDDRIQILQSFTAVETEGHAFKKAVLAIYVCGNVTFLIIFLSAINHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1MZM6-1", "uniprot_id": "F1MZM6_BOVIN", "id": "F1MZM6-1", "name": "Ferric reductase 1", "aln": "--------------------------------------------------------------------MTAPGFTVSAFILLLHVSFVANYPSGKVTKSCGGMIPEHGHTPQSHPAHNISVSQKTFRPGDQIKVTLSGPPFKGFLLEARDAENLSGPPVGSFTLIDSHVSQLLTCEDVQGSAVSHRSPSKKTEIKVFWDAPSGAPNHITFLATVVEKYKIYWVKIPGPVISQPNVPPFTTPEATI-APMPTVPSVSHLTRSFNASDCGNKKFCIRSPLNCDPEKERACVFLSFTRDDQSVMVEMSGPSKGYLSVAFSHDRWMGDDDAYVCILEDQIVHIQPSHLTGRSHPIMDFGDPLEDMAWRLVDGVMQCSFRRNITLPGVKNRFDLNASYYIFVADGAAVDGR-IHKHSQQPLITYEKYNVTGDPKNIGGSHSLLLLKVHGALMFVAWMTTVSVGVLIARFFKPVWSKA-LFGDAAWFQVHRTLMLTTSALTFIAFLLPFIYRGGWNWHAGYHPYLGFIVMVLAVLQLLLAAFRPPLHDPRRQMFNWTHWSMGTAARIIAVAAMFLGMDLPGLNLPGPWKTYAMIGFVAWHVGTEIILEIHAYRLSRKVEILDDDRIQILQSFTAAEAEGYVFKKVVLAIYVCGNLTFLTMFLSAINRL", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A8V0ZZD8-1", "uniprot_id": "A0A8V0ZZD8_CHICK", "id": "A0A8V0ZZD8-1", "name": "Ferric reductase 1", "aln": "MARVSLLSALEHPEGARGGGALFCSQSSGGAFSVLYGQNHFHDSSFLLFVEKREKRENCIVGKRPYPKMELPGLAFAVWMFICFRVSVDGYPNGKVREACASMVPCHGSSPKLSPEHVITVNRTEFKPGESVEVQLSGPDFEGFFIQARDADDLDSPAVGSFVLVDRRHSQLLTCGRTMNSAVSHTSKAKKKVVKVYWIAPGVAPKRVRFLATVVKKYKTFWVKIPGPDVSQPNAPFSTTPLYTTSEAVSTSHSVSYLTKPFNASGCGNTKFCLRNPSNCDPES-ASCFFLSFRQEKRSVVIEMSGASEGYLAFALSYDQWMGDDDAYLCINKDHHVSVSTAYLKGRSPPVLDSKNALEDVSWRLADGVLQCSFRRNISLPTYKGRFNMNVSYYIFLADGEASEGGPIYKHHRQPLITNGMYNVTGIPQDIGGSRSPRLIKAHGALMFVAWISTVSIGVVVARFFKPVWSHSFLFGKEIWFQVHRMLMLTTIMLTSFSFVLPFIYRGGWSKQAGFHPYLGCTVMALTIFQPLMAGFRPSPHAPRRQLFNWFHWSIGTTARILAVVTMFLGMDLPALDLPDPWDTYTMIGFVAWHVGTDALLEIHSYYLIRKVELIEDDRVQILQSLTSAEAEGNLFKQIVLTIYICGNIIFLVAFLAAINQV", "tax_id": 9031, "tax_name": "Chicken" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . ::... : * **.*:* :* .*:* *. :*: * * * *.: *:**:.::* *** *.**:::**:*::*..*.:*:*.*:* **:*** . **** : *. :**:* **. **.: **.***:*:* :*****.* :***.. *** * .:. .**:**:.*.* ***.***:*.* *****. :*.**** ::.:**::****.*.**::.*:*:*:********:** :*: * :..::*.*** *::* ..***::***.***:********:** *.** :* ***** *:* : :* *.:* :***** *:**. *:.:***:* *:*.*********::*** **::****:.***:: :: . **** : . . . ...:: * ** * . :**:***** **.*:::* *:* ***. * ****:*** ***:**:***:**.:********.*:**.. .**:* ***.**:**: :**:*:* * ****::::**:*****:* .*:** **: **::*:***: ** **:**.::", "identical_positions": 291, "similar_positions": 179, "identity": "43.96%" }, { "cls_id": "homologset.oma.834188", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A4X1UIY4-1", "uniprot_id": "A0A4X1UIY4_PIG", "id": "A0A4X1UIY4-1", "name": "RNA helicase aquarius", "aln": "-------------------------------------------------MTAPAQ----PKKIVAPTVSQINAEFVTQLACKYWAPHIKK-KSPFDIKVIEDIYEKEIVKSR-FAIRKIMLLEFSQYLENYLWMNYSPEVSS-KAYLMSICCMVNEKFRENVPAWETFKKKPDHFP------------FFFKCILKAALAET---DGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMGLQPARLELELK--KTPKLRKFWNLIKKNDEKMDPEAREQAYQERKFLSQLIQKFISVLKSVP----LSDPVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSNLVH--REEDGHLFSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVAEVDTRESLVKFFGPLSSNTLHQVASYLCLLPTLPKA--EDTTFDKEFLLELLVSRHERRISQIQQ-LNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEIRQDIEDSVSRMKP-------WQSEYGGVVFGGWARMAQPIVA-FTVVEVAKPNIGENWPTRVRADVTINLN-VRDHIKDEWEGLRKHDVCFLITVRPTKPYGTKFDRRRPFIEQVGLVYVRGCEIQGMLDDKGRVIEDGPEPRPNLRGE-------------------------------------SRTFRVFLDPNQYQQDMTNTIQNGAEDVYETFNIIMRRKPKENNFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIAT----LDFNDTFLSIEHLKASFPGHNVKVTVDDPALQIPPFRITFPVRSGKGKKRKDADGEDEDTEEAKTLIVEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPG-LTMVVGPPGTGKTDVAVQIISNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEEL----ETEKDFSRYGRVNYVLARRIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNKGNTL----PNVTEVSTFFPFHEYFAN----APQPIFKGRSYEEDMEIAEGCFR-----------HIKKIFTQLEEFRASELLRSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQD--------------------GFSR-LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQG--VGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCG----SNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLTARPLHLHIIPTEPFPTSRKN-GERPSHEVQIIKNMPQMANFVYNMYMHLIQTTHHYHQTLLQLPPAMVEEGEEVQSQDTELETEEEAMPAPADIMP-TLMDASSSQEASASQTEPTSNETETTSSQTGADSNPEATPAESKITATAAGPVATPAENNTPPDATSAPGETK--", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A3Q1MP16-1", "uniprot_id": "A0A3Q1MP16_BOVIN", "id": "A0A3Q1MP16-1", "name": "RNA helicase aquarius", "aln": "-------------------------------------------------MTAPAQ----PKKIVAPTVSQINAEFVTQLACKYWAPHIKK-KSPFDIKVIEDIYEKEIVKSR-FAIRKIMLLEFSQYLENYLWMNYSPEVSS-KAYLMSICCMVNEKFRENVPAWETFKKKPDHFP------------FFFKCILKAALAET---DGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMGLQPARLELELK--KTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFISVLKSVP----LSDPVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHVLVHCYLSNLVR--REEDGHLFSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVAEVDTRESLVKFFGPLSSNTLHQVASYLCLLPTLPKA--EDTTFDKGFLLELLVSRHERRISQIQQ-LNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEIRQDIEDSVSRMKP-------WQSEYGGVVFGGWARMAQPIVA-FTVVEVAKPNIGENWPTRVRADVTINLN-VRDHIKDEWEGLRKHDVCFLITVRPTKPYGTKFDRRRPFIEQVGLVYVRGCEIQGMLDDKGRVIEDGPEPRPSLRGE-------------------------------------SRTFRVFLDPNQYQQDMTNTIQNGAEDVYETFNVIMRRKPKENNFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIAT----LDFNDTFLSIEHLKASFPGHNVKVTVDDPALQIPPFRITFPVRSGKGKKRKDVDGEDEDTEEAKTLIVEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPG-LTMVVGPPGTGKTDVAVQIISNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEEL----ETEKDFSRYGRVNYVLARRIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNKSNTM----PDITEVSAFFPFHEYFAN----APQPIFKGRSYEEDMEIAEGCFR-----------HIKKIFTQLEEFRASELLRSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQD--------------------GFSR-LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYNWRYKNLGNLPHVQLLLEFSTANAGLLYDFQLINVEDFQG--VGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCG----SNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLTARPLHLHIIPTEPFPTSRKN-GERPSHEVQIIKNMPQMANFVYNMYMHLIQTTHHYHQTLLQLPPAMVEESEEVQSQETELETEEEAMSAQADIVPDEATDASSSQETSAS-------ETETTPNQTGASSSPEAIPAESEITG--TGPVTVPSENNTPHDVTSTPGETE--", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "O60306-1", "uniprot_id": "AQR_HUMAN", "id": "O60306-1", "name": "RNA helicase aquarius", "aln": "-------------------------------------------------MAAPAQ----PKKIVAPTVSQINAEFVTQLACKYWAPHIKK-KSPFDIKVIEDIYEKEIVKSR-FAIRKIMLLEFSQYLENYLWMNYSPEVSS-KAYLMSICCMVNEKFRENVPAWEIFKKKPDHFP------------FFFKHILKAALAET---DGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMGLQLARLELELK--KTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFISVLKSVP----LSEPVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSNLVR--REEDGHLFSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVAEVDTRESLVKFFGPLSSNTLHQVASYLCLLPTLPKN--EDTTFDKEFLLELLVSRHERRISQIQQ-LNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEIRQDIEDSVSRMKP-------WQSEYGGVVFGGWARMAQPIVA-FTVVEVAKPNIGENWPTRVRADVTINLN-VRDHIKDEWEGLRKHDVCFLITVRPTKPYGTKFDRRRPFIEQVGLVYVRGCEIQGMLDDKGRVIEDGPEPRPNLRGE-------------------------------------SRTFRVFLDPNQYQQDMTNTIQNGAEDVYETFNIIMRRKPKENNFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIAT----LDFNDTFLSIEHLKASFPGHNVKVTVEDPALQIPPFRITFPVRSGKGKKRKDADVEDEDTEEAKTLIVEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPG-LTMVVGPPGTGKTDVAVQIISNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEEL----ETEKDFSRYGRVNYVLARRIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNKGSTL----PDVTEVSTFFPFHEYFAN----APQPIFKGRSYEEDMEIAEGCFR-----------HIKKIFTQLEEFRASELLRSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQD--------------------GFSR-LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQG--VGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCG----NNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLTARPLHLHIIPTEPFPTTRKN-GERPSHEVQIIKNMPQMANFVYNMYMHLIQTTHHYHQTLLQLPPAMVEEGEEVQNQETELETEEEAMTVQADIIP-SPTDTSCRQETPAF-------QTDTTPSETGATSTPEAIPALSETTPTVVGAVSAPAEANTPQDATSAPEETK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CFQ3-1", "uniprot_id": "AQR_MOUSE", "id": "Q8CFQ3-1", "name": "RNA helicase aquarius", "aln": "-------------------------------------------------MAAPAQ----PKKIVAPTVSQINAEFVTQLACKYWAPHIKK-KSPFDIKVIEEIYEKEIVKSR-FAIRKIMLLEFSQYLENYLWMNYSPEVSS-KAYLMSICCMVNEKFRENVPAWETFKKKPDHFP------------FFFKCILKAALAET---DGEFSLHEQTLLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMGLQPARLELELK--KTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSRLIQKFISVLKSIP----LSEPVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSSLVH--REEDGHLFSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVAEVDARDSLVKFFGPLSSNTLHQVASYLCLLPTLPKN--EDTTFDKEFLLELLVSRHERRISQIQQ-LNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEIRQDIEDSVSRMKP-------WQSEYGGVVFGGWARMAQPIVA-FTVVEVAKPNIGENWPTRVRADVTINLN-VRDHIKDEWEGLRKHDVCFLITVRPTKPYGTKFDRRRPFIEQVGLVYVRGCEIQGMLDDKGRVIEDGPEPRPNLRGE-------------------------------------SRTFRVFLDPNQYQQDMTNTIQNGAEDVYDTFNVIMRRKPKENNFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIAT----LDFNDTFLSIEHLKASFPGHNVKVTVSDPALQIPPFRITFPVRSGKGKKRKDADGEEDDTEEAKTLIVEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPG-LTMVVGPPGTGKTDVAVQIISNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEEL----ETEKDFSRYGRVNYVLARRIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYMSRVKNSGTACPDAAPDAAQVATFFPFHEYFAN----APQPIFKGRSYEEDMEIAEGCFR-----------HIKKIFTQLEEFRASELLRSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQD--------------------GFSR-LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQG--VGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCG----NNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLTARPLHLHIIPTEPFPTSRKN-GERPPHEVQVIKNMPQMANFVYNMYMHLIQTTHHYHQTFLQLPPAMVEEGEEGQSQETEMEAEEETVSAQGNLTP-SPADASLSQETPAA-------QPDCS-------SQTEDTSAPCDIAT-AAEPVSAAAEAATPQDAESVPTETE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8C2MRH8-1", "uniprot_id": "A0A8C2MRH8_CRIGR", "id": "A0A8C2MRH8-1", "name": "RNA helicase aquarius", "aln": "-------------------------------------------------MAAPAQ----PKKIVAPTVSQINAEFVTQLACKYWAPHIKK-KSPFDIKVIEEIYEKEIVKSR-FAIRKIMLLEFSQYLENYLWMNYSPEVSS-KAYLMSICCMVNEKFRENVPAWETFKKKPDHFP------------FFFKCILKAALAET---DGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMGLQPARLELELK--KTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFISVLKSIP----LSEAVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSSLVH--REEDGHLFSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVAEVDARDSLVKFFGPLSSNTLHQVASYLCLLPTLPKN--EDTTFDKEFLLELLVSRHERRISQIQQ-LNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEIRQDIEDSVSRMKP-------WQSEYGGVVFGGWARMAQPIVA-FTVVEVAKPNIGENWPTRVRADVTINLN-VRDHIKDEWEGLRKHDVCFLITVRPTKPYGTKFDRRRPFIEQVGLVYVRGCEIQGMLDDKGRVIEDGPEPRPNLRGE-------------------------------------SRTFRVFLDPNQYQQDMTNTIQNGAEDVYDTFNVIMRRKPKENNFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIAT----LDFNDTFLSIEHLKASFPGHNVKVTVNDPALQIPPFRITFPVRSGKGKKRKDADGEEDDIEEAKTLIVEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPG-LTMVVGPPGTGKTDVAVQIISNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEEL----ETEKDFSRYGRVNYVLARRIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISRVKNTGSTS----PDAAEVASFFPFHEYFAN----APQPIFKGRSYEEDMEIAEGCFR-----------HIKKIFTQLEEFRASELLRSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQD--------------------GFSR-LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQG--VGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCG----NNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLTARPLHLHIIPTEPFPTSRKN-GERPPHEVQVIKNMPQMANFVYNMYMHLIQTTHHYHQTFLQLPPAMVEEGEEVQSQETEMEAEEETMTAQANIIP-SPAEASLSQETPAS-------QPESSNQTEAASSEMEDISALCDTAA-AAEPVSAAAGASTLEGAASVPAETR--", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "A0A8V0XHD1-1", "uniprot_id": "A0A8V0XHD1_CHICK", "id": "A0A8V0XHD1-1", "name": "RNA helicase aquarius", "aln": "MEAALVPAPRPGTASRRGAFPFPSVPARSGPRATARVAEAAALPGAGGVMAAPAASAAPPKKIVAPTVSQINAEFVTQLANKYWAPHAKK-KLSFDSKVIEDVYAKEIVKSK-FAIRKIMLLEFSQYLENYLWMNYSPKVSS-KAYLMSICCMVNEKFRENVPAWETFKKKSEHFP------------FFFKCILEASLVEN---DNEFSLHEQTILLLFLDHCFNSLEVDLIRGQVQQLISLPMWMALQPKRLEQELK--KTPKLRKFWNLIKKNDEKMDEEARMQAYRERRFLSQLIQKFISVLKSIP----VSGPISMDKVHYCERFIELMIDLEALLPTRRWFNTVLDDSHLVVHCYLSSLAK--REKEGHLFCQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVAAVDTRDALVKLFGPLSSNMLHQVASYLCLLPSLPEG--NDTSYEKEFLLELLVSRHERRISQIQQ-LNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEIRQDIEDSVSRMKP-------WLSEYGGVVFGGWARMAQPIVS-FTVVEVAKPNIGENWPMRVRADVTINLN-VRDSIKDEWEGLRKHDVCFLVTVRPTQPYGTKFDRRRPFVEQTGLVYVRGCEIQGMLDEKGRVIEEGPEPKPRLKGD-------------------------------------CRTYRVFLDPNQYQQDMTNTIQNGAEDVYETFNIIMRRKPKENNFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIAS----LDFNDTFLSIDHLKASFPGYNIKVTVDNPELQVPPFRITFPITGGRGKKRKEDENEEK-SEEAKTLIVEPHIIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPG-LTMVVGPPGTGKTDVAVQIISNLYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEEL----ETEKDFSRYGRVNYVLARRLELLREVGRLQESLGVPGDVSYTCETAGHFFLYQVMSRWEEYISKVKVKGGKL----PDVTDVSSFFPFHQYFAN----APQPIFRGRSYEEDMEIAEGCFR-----------HLKKIFTQLEEFRAFELLRSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVELGFKYDNILMEESAQILEIETFIPLLLQNPQD--------------------GFSR-LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYNWRYKNLGNLPHVQLMPEFRTANAGFLYDFQLINVEDFNG--VGESEPNPYFYQNLGEAEYVVAVFMYMCLLGYPADRISILTTYNGQKHLIRDVINQRCG----NNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTKAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLTARPLHLHIIPTECFPAARQN-GEPPAHQIHVIKNMPQMANFVYNMYMHMIQSTRHYQQRLLP-PPAMVEEPETTQTQESEAEVEVHGIREDAEENK--VEEVVVKEEELKA-------------------SEVDEHRTMPEHPG-----RDSDSEDSEPEDENEK-------", "tax_id": 9031, "tax_name": "Chicken" }, { "uniprot_ac": "Q7KSN8-1", "uniprot_id": "Q7KSN8_DROME", "id": "Q7KSN8-1", "name": "RNA helicase aquarius", "aln": "--------------------------------------MKRRSQTRAEQAVPPAKTT--KENSGSLTVSQLSSDVIWQLASQYWTPDTKADHLPYSAKIIERIYNEEIGDGGGHSARRINMLEFSQYLEQYLWPHYQRETAT-HAHLMSIVIMANEKFRERVEVWTVFEKLPDQYP------------AFFRHVLESCLPSKKAKEASSTLRERTALLMFINHCFNSMEIELCREQAKRLVSLSMWHCLQPRRREQELR--EVPEWRKYWKRLLKKEK----DSKPEVLWERHFMQNLIIDFLHILESIP----AEGEVPRNVVHYCERFLEFIIDLEALLPTRRFFNTVLDDCHLIVRALLSPLVR--REE-GKLFGQLLDMLKFYTRFEINDVTGSSLTDHDMTQLHYKKITSLQRAVFAKFPSLRVFALSNVATVDNRESLEQHFGGLDGKGLLQIATFLNLVPEEVVSPLDWHRVDEQFLRELLITRHERRCSQLEA-LNEMPLYPTEQIIWDENVVPSEYYSGDSCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEIRQDIEDAVSRMLP-------WKSEDGDVVFGGWARMALPIAS-FAVVEVAKPHLGEKKPSRVRADVGVTLS-VRREIKAEWENLRKHDVCFLITVKPTQPYGTKYKHREPFVPQVGLVSVRGCEVEGMLDANGRVIEDGPEPRPQLQGE-------------------------------------NRCYRVWLDSNQYRLDMD-DLQEGADDVYESFNILMRRKPKENNFKAVLETIRHLMNTECVVPPWLHDILLGYGDPGAAHYSNMPNQERS----LEFNDTFMDYNHLEASFPQYNLKCEVP-VENRQPPFRLIFEDVPIQKESDGEDPEEKPEEKLTKSILVQPYKYEARGPYPSDKPKQNSIRFTPTQVEAIRAGMQPG-LTLVVGPPGTGKTDVAVQIISNIYHNHPNQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEAL----ETEKDYSRYGRVNYVLAKRMDLLSQVQKLQEALGVSGDNAYTCETAGYFYLYNVMARWEKFQSQISVHKGEAD-AEKLRAEFEKEFPFGKFFAD----APQPLFKGANYDELMDIACSNFR-----------YISDIFNELEEFRAFELLRTGLDRSKYLLVKEAKIIAMTCTHAALKRKELVNLGFRYDNILMEESAQILEIETFIPLLLQNPLD--------------------GLNR-LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRLVRLGVPTVDLDGQGRARASICSLYKWRYKKLEDLQHIFERDEYKQANPGFVHDYQLINVEDFKG--VGESEPNPYFYQNLAEAEYIVAVYMYMRLLGYPAAKISILTTYNGQKHLIRDVINARCG----NNPLIGWPHKITTVDKYQGQQNDYILISLVRTKAVGHLRDVRRLVVAMSRARLGLYVFGRVSLFKNCLELQQTFKLLTQRPLKLSLVPEDKFPTDRLASAAVASQDIKTVENMSEMAQFVYERYMAKMEELKG----------TLPSEEELEAMRNQLLQEDEESVPEASEEPP---EKRAAKEEPLSK-------------KKTTEAFKPTPILNEINVDDTEMGQREQIEEEATDQDKTQESAPAEES", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q555Z2-1", "uniprot_id": "Q555Z2_DICDI", "id": "Q555Z2-1", "name": "Intron-binding protein aquarius", "aln": "---------------------------MVGNNKSNKHGTDNEENDDNRKKQKLDNNSNNSVSSNKLTLSEVLSDEITKLSKQQWLKEVNT--KTFDSNLVEKIYKDEMLKSD----QRVQLLELSHYLENYLWPNFNKTTSTNKYHIMSILMMVNEKSKEGLNSFQTFHSKSSSSSDDNSEQEESSPSSSFKNLFESLLQID---LSELTDIEKCNFIKFFINAFQNVEDVLVRNECLKIVSYPIWLHLSSGRFQQESQSLSEPLEKKLRLFKKKIEKLSNNNSNSIEIKYSNFLLDLMKQFIESLNNLERLKSSNFTQFKESLNYCERFLEFMIDLMTQITTRRFFFALFDDFHFILKTSQSEFLKSNDDKSKSVLEGLLGILKVYYNFDIDNFTGEELTKDQATGIHYQNIQELQKIVFKNFPEIKEIALRNVSFVESKSDLLNIISTLSQERLNELS--------------------------LVLMKYKKKESVIEQSINRVSLYPTEKLLWNETAIPNTNYNNEKALPLPKLNLQFLSFNDYLMRNFVLIRLESAYEIREDIQDSVKRLSPKFIQSNTNTTNNNKTTFTGWSRMSLQLSTPFKIINVQPPIIGEIKPKQVIGVVNISTSSCKPHIRDEWNSIKEHDILFLITIQLNNNNTNNTNTNNNNFSDI-VKHVRGCEVIEIIDNNNNNLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNSNNKNNNNNNNNYNNYSKAFKVSLDTNQYQEDLESSSLK----LYDTFNIVVRRNPKENNFKAVLDTITSLFNCKDYLPDWFSSIFLGYPSSNNNSNNNNEGEEKKENEFILFNDTFLNLNHINKVYNDKTIEITDKLKEEQENNNNNNNNFKIKFNNENNSILVDTYNNNNDNNNNNNNIIIKKEN---LEEIKRNKIEFTSKQIEAISSGMKRDNLTLIVGPPGTGKTDIAVQIISNIYHSSPNERTLIITHSNQALNQLFEKIYRLDINERYLLRLGHGQKQLSSTNSTQKDFTKTGRIDFWLDLRLKKLDQVDKLAKSISVTDDVSYTCDTALHFFSYHILSRFEKFQYDLSLLQDDDDGDEKKIKFIKENYPFKKFFIENSILKNDKLFDTTTTTTSVDNHHQSLLNIKKNLIELWNYIKEIFKELEECKVFELLKSPNDRYNYLLLKQSKIVAMTCTHAALKRNELLRLGFKFDNLLMEESAQISDIESFIPLQLQLNSNEIGDAIIGVDGDDNGNGNGNNISRGLKRVILIGDHNQLPPIVQNQSLAKYSHFDQSLFTRLIRLEIPHITLDRQGRSRPSISELFSWKYKGLQDLPLVKEQLQFKLANPGLAYDYQLINVDESDGYGVGESEPTPYFYQNLGEAEYIVAMFQYLIAIGYPSEKITVLTTYNGQKNLLRDVFKAKCTPQDPKKTQYGLPLKITTIDKYQGQQNDIILLSLVRTKQYGHIRDVRRLIVAMSRARLGLYIFCKKQFFQNCYETSMVFSKLLKRPDKLIIIKSEQYPITSEN-----ARQINSKLDENDCFEIQNSFHMKSLVESNE---------------------------------------------------------------------------------------------------------------------", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 469, "similar_positions": 465, "identity": "27.93%" }, { "cls_id": "homologset.oma.834228", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A9J7FPC9-1", "uniprot_id": "A0A9J7FPC9_CRIGR", "id": "A0A9J7FPC9-1", "name": "Histone acetyltransferase KAT5", "aln": "MAEVVSPVPGAGRREPGEVGRARGPPVADPGAALSP-QGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLDL-KKIQFPKKE-AKTPTKNGLPG-----------SRPGSPEREVP---------ASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSP-ATPVPSESAPASVFPQNGSARRAVAAQPGRKRKSNCLGTD---------------------EDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLT-----------------KCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPE-----KPLSDLGLLSYRSYWSQTILEILMGLKSE--SGERPQITIN------------EISEITSIKKE-----DVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKR------LLRIDSKCLHFTPKDWSKRGKW---------", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "A0A3Q1MIR9-1", "uniprot_id": "A0A3Q1MIR9_BOVIN", "id": "A0A3Q1MIR9-1", "name": "Histone acetyltransferase KAT5", "aln": "MAEVVSPVPGAGRREPGEVGRARGPPVADPGAALSP-QGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLDL-KKIQFPKKE-AKTPTKNGLPG-----------SRPGSPEREVP---------ASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSP-ATPVPSETAPASVFPQNGSARRAVAAQPGRKRKSNCLGTD---------------------EDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTALPVLYLCEFCLKYGRSLKCLQRHLT-----------------KCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPE-----KPLSDLGLLSYRSYWSQTILEILMGLKSE--SGERPQITIN------------EISEITSIKKE-----DVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKR------LLRIDSKCLHFTPKDWSKRGKW---------", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q99MK2-1", "uniprot_id": "KAT5_RAT", "id": "Q99MK2-1", "name": "Histone acetyltransferase KAT5", "aln": "---------------------------------MAE-VGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLDL-KKIQFPKKE-AKTPTKNGLPG-----------SRPGSPEREVP---------ASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSP-ATPVPSETAPASVFPQNGSARRAVAAQPGRKRKSNCLGTD---------------------EDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLT-----------------KCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPE-----KPLSDLGLLSYRSYWSQTILEILMGLKSE--SGERPQITIN------------EISEITSIKKE-----DVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKR------LLRIDSKCLHFTPKDWSKRGKW---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CHK4-1", "uniprot_id": "KAT5_MOUSE", "id": "Q8CHK4-1", "name": "Histone acetyltransferase KAT5", "aln": "---------------------------------MAE-VGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLDL-KKIQFPKKE-AKTPTKNGLPG-----------SRPGSPEREVP---------ASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSP-ATPVPSETAPASVFPQNGSARRAVAAQPGRKRKSNCLGTD---------------------EDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLT-----------------KCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPE-----KPLSDLGLLSYRSYWSQTILEILMGLKSE--SGERPQITIN------------EISEITSIKKE-----DVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKR------LLRIDSKCLHFTPKDWSKRGKW---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92993-1", "uniprot_id": "KAT5_HUMAN", "id": "Q92993-1", "name": "Histone acetyltransferase KAT5", "aln": "---------------------------------MAE-VGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLDL-KKIQFPKKE-AKTPTKNGLPG-----------SRPGSPEREVP---------ASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSP-ATPVPSETAPASVFPQNGAARRAVAAQPGRKRKSNCLGTD---------------------EDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLT-----------------KCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPE-----KPLSDLGLLSYRSYWSQTILEILMGLKSE--SGERPQITIN------------EISEITSIKKE-----DVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKR------LLRIDSKCLHFTPKDWSKRGKW---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RRK4-1", "uniprot_id": "F1RRK4_PIG", "id": "F1RRK4-1", "name": "histone acetyltransferase", "aln": "---------------------------------MAE-VGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLDL-KKIQFPKKE-AKTPTKNGLPG-----------SRPGSPEREVP---------ASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSP-ATPVPSETAPASVFPQNGSARRAVAAQPGRKRKSNCLGTD---------------------EDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLT-----------------KCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFMRSVKSPASRRRTSSPLYSTSTSSTTTRASISSHCRRTSWTGMNGLCSSGFFGSTPSVCTSLPRTGARGESGDQALPISSAGKASRTGADSLSRPHWG-LQEAQQGETGLRTAPQGEDRPGKGQLVPSTKESSGLRSTPRSAGCRPRPAVNQGPEGARQLCTVR", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "A0A8M9QDW0-1", "uniprot_id": "A0A8M9QDW0_DANRE", "id": "A0A8M9QDW0-1", "name": "Histone acetyltransferase KAT5", "aln": "---------------------------------MAEPTVEIVEGCRLPVLRKNQENEDEWPLAEILSVKDIPGRKLYYVHYIDFNKRLDEWVTPDRLDL-KKLQFPKKE-AKTPTKNGLPG-----------SRPSSPEREVRKSLDLNVQSASAPSRGKTLPTPKRKAESVSLATQ---VTAATPVPSLPSS--AEASQASVYPAMRDSSF-SIKAREEHEQLTSLTTNGTTRRLIPSQPGRKRK-NCVGTEEIVKVFQNNSPRSSTVYLPPGEDSQDSSDGIPSAPRMTGSLVSDRSHDDIITRMKNIDCIELGRHRLKPWYFSPYPQELTTLPILYLCEFCLKYLKSLKCLQRHLVRAVLGPDVTHSQHQIKTKCNLRHPPGNEIYRKGTISFFEIDGRKNKMYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDSKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPE-----KPLSDLGLLSYRSYWSQTILEILMNLKSE--NGERPQMTIN------------EISEITSVKKE-----DVISTLQYLNLINYYKGQYILTLSEDIVEGHERAMHKR------HLRIDSKCLHFTPKDWSKRGKW---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q960X4-1", "uniprot_id": "TIP60_DROME", "id": "Q960X4-1", "name": "Histone acetyltransferase Tip60", "aln": "------------------MKINHKYEFDDDVASICESTAALTEGCRLPVR---MHKTDDWPLAEIVSIKELDGRRQFYVHYVDFNKRLDEWVNEEDLYT-RKVQFPRRDGSQTGTSTGVTTPQRHHSLAGSVSRPTSPQHPGSG----ALAAIPQTPTGASGSVPPPAGIPNSVAPPGTPSSGGELVNGNNLAAALQKRINRKRKNHGGSAHGHHSLTSQQQQSHPHPTTPQTPTATPVHVTGDGLISGAAND----------------------DGDGSQDGKTPTPRQSGSMVT--HQDDVVTRMKNVEMIELGRHRIKPWYFSPYPQELCQMPCIYICEFCLKYRKSRKCLERHLS-----------------KCNLRHPPGNEIYRKHTISFFEIDGRKNKVYAQNLCLLAKLFLDHKTLYYDTDPFLFYVMTEFDSRGFHIVGYFSKEKESTEDYNVACILTMPPYQRKGYGKLLIEFSYELSKFEGKTGSPE-----KPLSDLGLLSYRSYWAQTILEIFISQNPS-TDGEKPTITIN------------DICECTSIKKE-----DVISTLQNLNLINYYKGQYIVCINRVIIEQHRRAMDKR------KIRIDSKCLHWTPKDWSKRSK----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08649-1", "uniprot_id": "ESA1_YEAST", "id": "Q08649-1", "name": "Histone acetyltransferase ESA1", "aln": "--------------------MSHDGKEEPGIAKKINSVDDIIIKCQCWVQ-----KNDEERLAEILSINTRKAPPKFYVHYVNYNKRLDEWITTDRINLDKEVLYPKLK---------------------------ATD---------------------------------------------------------EDNKKQKKKKATNTSE--TPQDSLQDGVDGFSRENTDVMDLDN-------LNVQGIK----------------------DENISHEDEIKKLRTSGSMTQN---PHEVARVRNLNRIIMGKYEIEPWYFSPYPIELTDEDFIYIDDFTLQYFGSKKQYERYRK-----------------KCTLRHPPGNEIYRDDYVSFFEIDGRKQRTWCRNLCLLSKLFLDHKTLYYDVDPFLFYCMTRRDELGHHLVGYFSKEKESADGYNVACILTLPQYQRMGYGKLLIEFSYELSKKENKVGSPE-----KPLSDLGLLSYRAYWSDTLITLLVEHQKE--------ITID------------EISSMTSMTTT-----DILHTAKTLNILRYYKGQHIIFLNEDILDRYNRLKAKK------RRTIDPNRLIWKPPVFTASQLRFAW------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: * : *: ****:*:: . :****:::*******:. : : ::: :*: . :.: : : . . . . . * : * :. * :**:. . ::*::*:: * :*::.::******** ** :*: :* *:* * * :*: ** ***********. :*********:: :.:*****:* **********.****** **. * *.*:**********::.********:* *** ********* .:.. .: :.. .. * * :: * : . : . : :* . * : : : . :*: : : : .. * ", "identical_positions": 133, "similar_positions": 104, "identity": "20.56%" }, { "cls_id": "homologset.oma.834229", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1RIR8-1", "uniprot_id": "F1RIR8_PIG", "id": "F1RIR8-1", "name": "Histone acetyltransferase", "aln": "MAAQGAAAAVAAATSGVAGEGDPGPGENAAVEGTAPSPGRVSP--------PTPARGEPEVTVEIGETYLCRRPDSTWHSAEVIQSRVNDQEGRE--EFYVHYVGFNRRLDEWVDKNRLALTKTVKDAVQKNSEKYLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRDFRG--TLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTP-KLVEEHLKSAQYKKPPITVDSVCLKWAPPKHKQVKLSKK", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "F1MP98-1", "uniprot_id": "F1MP98_BOVIN", "id": "F1MP98-1", "name": "Histone acetyltransferase", "aln": "MAAQGAAAAVAAATSGVAGEGEPGPGENAAVEGTAPSPGRISP--------PTPARGEPEVTVEIGETYLCRRPDSTWHSAEVIQSRVNDQEGRE--EFYVHYVGFNRRLDEWVDKNRLALTKTVKDAVQKNSEKYLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRDFRG--TLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTP-KLVEEHLKSAQYKKPPITVDSVCLKWAPPKHKQVKLSKK", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "Q9H7Z6-1", "uniprot_id": "KAT8_HUMAN", "id": "Q9H7Z6-1", "name": "Histone acetyltransferase KAT8", "aln": "MAAQGAAAAVAAGTSGVAGEGEPGPGENAAAEGTAPSPGRVSP--------PTPARGEPEVTVEIGETYLCRRPDSTWHSAEVIQSRVNDQEGRE--EFYVHYVGFNRRLDEWVDKNRLALTKTVKDAVQKNSEKYLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRDFRG--TLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTP-KLVEEHLKSAQYKKPPITVDSVCLKWAPPKHKQVKLSKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D1P2-1", "uniprot_id": "KAT8_MOUSE", "id": "Q9D1P2-1", "name": "Histone acetyltransferase KAT8", "aln": "MAAQGATAAVAATTSGTVGEGEPGPGENAAVEGPARSPGRVSP--------PTPARGEPEVTVEIGETYLCRRPDSTWHSAEVIQSRVNDQEGRE--EFYVHYVGFNRRLDEWVDKNRLALTKTVKDAVQKNSEKYLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKFEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRDFRG--TLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTP-KLVEEHLKSAQYKKPPITVDSVCLKWAPPKHKQVKLSKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9LXD7-1", "uniprot_id": "MYST2_ARATH", "id": "Q9LXD7-1", "name": "Histone acetyltransferase of the MYST family 2", "aln": "---MGSSANTETNGNAPPPSSNQKPPATNGVDGSHPPPPPLTPDQAIIESDPSKKRKMGMLPLEVGTRVMCRWRDGKHHPVKVIERRRIHNGGQNDYEYYVHYTEFNRRLDEWTQLDQLDLDS-VECAVDEKVEDKVTSLK------MTRHQKRKIDET-HIEG-HEELD---AASLREHEEFTKVKNISTIELGKYEIETWYFSPFPPEYNDCVKLFFCEFCLNFMKRKEQLQRHMRKCDLKHPPGDEIYRSGTLSMFEVDGKKNKVYAQNLCYLAKLFLDHKTLYYDVDLFLFYVLCECDDRGCHMVGYFSKEKHSEEAYNLACILTLPSYQRKGYGKFLIAFSYELSKKEGKVGTPERPLSDLGLLSYRGYWTRVLLEILKKHKG--NISIKELSDVTAIKAEDILSTLQSLELIQYRKGQHVICADP-KVLDRHLKAAG--RGGLDVDASKLIWTPYKDQS------", "tax_id": 3702, "tax_name": "Mouse-ear cress" }, { "uniprot_ac": "Q9VAV6-1", "uniprot_id": "Q9VAV6_DROME", "id": "Q9VAV6-1", "name": "Histone acetyltransferase", "aln": "-------------------------MDKENRSGDHLKYQPLGD-----------QDGISSKLPDIPRALQLTNAKESSATRGLGQSASKSEMGKS-------QLQNDSSLQKNIQETKTITGSCIEAQRIGATPKKQLEGVKEPNMISLLHTNASSNVDDRQRQETIDNEKSDVQKEKEDAKVKVIRNIEKVQFGRYEIETTSSSPYPVINDKATTIYVCEFCLKYMCLRKSYSYHLYDCKKRCPPGSLLYRKDNIYIYEVDGHKEQLYCQCLCLMSKLFLENKKILYSSSSFLFYILCLKDKDGEHFAGYFAREKTMLN-INLNCILVLPPYMRKGYGKLLIDLSYEISRREACIGGPKKPLSKVARLCYLSYWGHILLNLLRHHSSPDLVTIEELSKATGFREEDIISTLEFMGMTKYYKVDHIMFYTTSSIIEDRRGLAQFKKPRLTIHRNRLSWKTPTGRK------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .* : :: . . . : : : *:. : *:: : : . :: . . : : . : : . : : . :*. .. :: :..:.:*.***:: **:* .. .::.**:**::* .:. *: .*. : ***. :**...: ::****:..::*.* ** ::****::*.: :. . *:**:* * * *:.***::** : *: ***.**.* *:****:** :***:*: *. :* *::***.:. *.* .** :**::*:.. . ::*::**. *.: :**:***: : : :* * :*:: . .::: : * : : :. * * . . :. ", "identical_positions": 94, "similar_positions": 148, "identity": "19.96%" }, { "cls_id": "homologset.oma.834230", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O95251-1", "uniprot_id": "KAT7_HUMAN", "id": "O95251-1", "name": "Histone acetyltransferase KAT7", "aln": "--MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVRNLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTADHDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKVRAQSRDKQIEERMLSHRQDDNNRHATRHQAPTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A480XKQ4-1", "uniprot_id": "A0A480XKQ4_PIG", "id": "A0A480XKQ4-1", "name": "Histone acetyltransferase", "aln": "--MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVRNLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVEFSDRETKNTADHDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKVRAQSRDKQIEERMLSHRQDDNNRHATRHQAPTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q5SVQ0-1", "uniprot_id": "KAT7_MOUSE", "id": "Q5SVQ0-1", "name": "Histone acetyltransferase KAT7", "aln": "MAIGVVKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVRNLPSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTADHDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKVRAQSRDKQIEERMLSHRQDDNNRHATRHQAPTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q810T5-1", "uniprot_id": "KAT7_RAT", "id": "Q810T5-1", "name": "Histone acetyltransferase KAT7", "aln": "MAIG-VKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVRNLPSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQAVDFSDRETKNTADHDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKVRAQSRDKQIEERMLSHRQDDNNRHATRHQAPTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ********************************************************** *******************************************.*:**********************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************", "identical_positions": 604, "similar_positions": 3, "identity": "98.53%" }, { "cls_id": "homologset.oma.834281", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BRA2-1", "uniprot_id": "TXD17_HUMAN", "id": "Q9BRA2-1", "name": "Thioredoxin domain-containing protein 17", "aln": "MARYEEVSVSGFEEFHRAVEQHN--GKTIFAYFTGSKDAGGKS-WCPDCVQAEPVVREGLKHISEGCVFIYCQVGEKPYWKDPNNDFRK--NLKVTAVPTLLKYGT-----PQKLVESECLQANLVEMLFSED-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AAA9T355-1", "uniprot_id": "A0AAA9T355_BOVIN", "id": "A0AAA9T355-1", "name": "Thioredoxin domain-containing protein 17", "aln": "MASYEEVSVSGYEEFMQVVEQHS--DKTIFAYFSGSKDAEGKS-WCPDCVQAEPVVREGLKHVGEGCVFIYCQVGEKPYWKDPNNDFRK--NLKLTAVPTLLKYGT-----PQKLVESECLQANLVEMLFSED-", "tax_id": 9913, "tax_name": "Bovine" }, { "uniprot_ac": "A0A286ZZM7-1", "uniprot_id": "A0A286ZZM7_PIG", "id": "A0A286ZZM7-1", "name": "Thioredoxin domain-containing protein 17", "aln": "MARYEEVSVSGYEEFIQAVKQHN--GKTIFAYFSGSKDAEGKS-WCPDCVQAEPVVREGLKHTVEGCVFIYCQVGERLYWKDPNNDFRK--KLKLTAVPTLLKYGT-----PQKLVESECLQTNLVEMLFSEE-", "tax_id": 9823, "tax_name": "Pig" }, { "uniprot_ac": "Q9CQM5-1", "uniprot_id": "TXD17_MOUSE", "id": "Q9CQM5-1", "name": "Thioredoxin domain-containing protein 17", "aln": "MATFEEVSVLGFEEFDKAVKEHE--GKTIFAYFSGSKDTEGKS-WCPDCVEAEPVIREGLKHVTEDCVFIYCQVGDKPYWKDPNNDFRQ--KLKITAVPTLLKYGT-----PQKLVESECCQSSLVEMIFSED-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A3L7GM56-1", "uniprot_id": "A0A3L7GM56_CRIGR", "id": "A0A3L7GM56-1", "name": "Thioredoxin domain-containing protein 17", "aln": "MATCKEVNVSGFEEFDQAVKEHK--GKTIFAYFSGSKDAEGKS-WCPDCVEAEPVVREGLKSVTEDCVFIYCQVGDKSYWKDPNNDFRQ--QLQVTAVPTLLKYGT-----PQKLVESECSQANLVEMIFSED-", "tax_id": 10029, "tax_name": "Chinese hamster" }, { "uniprot_ac": "Q6DBT3-1", "uniprot_id": "TXD17_DANRE", "id": "Q6DBT3-1", "name": "Thioredoxin domain-containing protein 17", "aln": "MSKYEEVAVHGYEEFCKAVSDRK--GKEIFAYFSGDKDEHGKS-WCPDCVKAEPVVRAELPHLPEGTVFIYCQVGDRPYWKDSNNDFKK--TLKLTGVPTLLRYGT-----PQKLVEEECFKADLVRMMFTED-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMQ9-1", "uniprot_id": "Q9VMQ9_DROME", "id": "Q9VMQ9-1", "name": "Thioredoxin domain-containing protein 17", "aln": "--MVVTHNVKGYDEFTKKMEELENGDEPVHVLFSGGKDEKGES-WCPYCVKAEPVIHDALKKAPGNSHFVHVDVGERAYWKDLNCPFRKDPNTHLIFLPTLLRWKR-----PQRLDGERCSNQDLVEMMFEDED", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B0G106-1", "uniprot_id": "B0G106_DICDI", "id": "B0G106-1", "name": "", "aln": "MGLVNKIVVTNADGFDKTLQDSLKSNETVFVQFISSIDKTTCSLWCRDCQVSEPIVNSVFENLPKNITYIECQIERE--GGNPNHPYRTNPTLKLTAIPTLIVLLTKDGPKPKTLVEEDLAKEENVKQFVNEYL", "tax_id": 44689, "tax_name": "Social amoeba" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : * : :.: .: :.. * .. * * ** * :**::. : . :: :: . : * :: :: :***: *: * . : . *. :. : ", "identical_positions": 17, "similar_positions": 39, "identity": "12.69%" } ]