[ { "cls_id": "homologset.agr.SGD:S000004665", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M4W7-1", "uniprot_id": "F1M4W7_RAT", "id": "F1M4W7-1", "name": "Cleavage stimulation factor subunit 3", "aln": "----------MSGDAAAEQAAEYVPEKVKKAEKKLEENPYDLDAWSILIREAQNQP-IDKARKTYERLVAQFPSSGRFWKLYIEAEIKAKNYDKVEKLFQRCLMKVLH---IDLWKCYLSYVRETKGKLPSYKEK---MAQAYDFALDKIG-MEIMSYQIWVDYINFLKGVEAVGSYAENQRITAVRRVYQRGCVNPMINIEQLWRDYNKYEEGINIHLAKKMIEDRSRDYMNARRVAKEYETVMKGLDRNAPS---------VP-PQNTPQEAQQVDMWKKYIQWEKSNPLRTEDQTLITKRVMFAYEQCLLVLGHHPDIWYEAAQYLEQSSK--------LLAEKG--------------------------------DMNNAKLFSDEAANIYERAISTLLKKNMLLYFAYADYEESRMKYEKVHSIYN-RLLAIEDIDPTLVYIQYMKFARRAEGIKSGRMIFKKAREDARTR-HHVYVTAALMEYYCSKDKSVAFKIFELGLKKYGDIPEYVLAYIDYLSHLNEDNNTRVLFERVLTSGSLPPEKSGEIWARFLAFESNIGDLASILKVEKRRFTAFR--EEYEGKETALLVDRYKFMDLYPCSASELKALGYKDVSRAKLAAIIPDPVVAPSIVPVLKDEVDRKPEYPKPDTQQMIPFQPRHLAPPGLHPVPGGVFPVPPAAVVLMKLLPPPICFQGPFVQVDELMEIFRRCKIPNTVEEAVR--IITGGAPELAVEGNGPVESS----------AVLTKAVKRPNEDSDEDEEKGAVVPPVHDIYRARQQKRIR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LI7-1", "uniprot_id": "CSTF3_MOUSE", "id": "Q99LI7-1", "name": "Cleavage stimulation factor subunit 3", "aln": "----------MSGDAAAEQAAEYVPEKVKKAEKKLEENPYDLDAWSILIREAQNQP-IDKARKTYERLVAQFPSSGRFWKLYIEAEIKAKNYDKVEKLFQRCLMKVLH---IDLWKCYLSYVRETKGKLPSYKEK---MAQAYDFALDKIG-MEIMSYQIWVDYINFLKGVEAVGSYAENQRITAVRRVYQRGCVNPMINIEQLWRDYNKYEEGINIHLAKKMIEDRSRDYMNARRVAKEYETVMKGLDRNAPS---------VP-PQNTPQEAQQVDMWKKYIQWEKSNPLRTEDQTLITKRVMFAYEQCLLVLGHHPDIWYEAAQYLEQSSK--------LLAEKG--------------------------------DMNNAKLFSDEAANIYERAISTLLKKNMLLYFAYADYEESRMKYEKVHSIYN-RLLAIEDIDPTLVYIQYMKFARRAEGIKSGRMIFKKAREDARTR-HHVYVTAALMEYYCSKDKSVAFKIFELGLKKYGDIPEYVLAYIDYLSHLNEDNNTRVLFERVLTSGSLPPEKSGEIWARFLAFESNIGDLASILKVEKRRFTAFR--EEYEGKETALLVDRYKFMDLYPCSASELKALGYKDVSRAKLAAIIPDPVVAPSIVPVLKDEVDRKPEYPKPDTQQMIPFQPRHLAPPGLHPVPGGVFPVPPAAVVLMKLLPPPICFQGPFVQVDELMEIFRRCKIPNTVEEAVR--IITGGAPELAVEGNGPVESS----------AVLTKAVKRPNEDSDEDEEKGAVVPPVHDIYRARQQKRIR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12996-1", "uniprot_id": "CSTF3_HUMAN", "id": "Q12996-1", "name": "Cleavage stimulation factor subunit 3", "aln": "----------MSGDGATEQAAEYVPEKVKKAEKKLEENPYDLDAWSILIREAQNQP-IDKARKTYERLVAQFPSSGRFWKLYIEAEIKAKNYDKVEKLFQRCLMKVLH---IDLWKCYLSYVRETKGKLPSYKEK---MAQAYDFALDKIG-MEIMSYQIWVDYINFLKGVEAVGSYAENQRITAVRRVYQRGCVNPMINIEQLWRDYNKYEEGINIHLAKKMIEDRSRDYMNARRVAKEYETVMKGLDRNAPS---------VP-PQNTPQEAQQVDMWKKYIQWEKSNPLRTEDQTLITKRVMFAYEQCLLVLGHHPDIWYEAAQYLEQSSK--------LLAEKG--------------------------------DMNNAKLFSDEAANIYERAISTLLKKNMLLYFAYADYEESRMKYEKVHSIYN-RLLAIEDIDPTLVYIQYMKFARRAEGIKSGRMIFKKAREDTRTR-HHVYVTAALMEYYCSKDKSVAFKIFELGLKKYGDIPEYVLAYIDYLSHLNEDNNTRVLFERVLTSGSLPPEKSGEIWARFLAFESNIGDLASILKVEKRRFTAFK--EEYEGKETALLVDRYKFMDLYPCSASELKALGYKDVSRAKLAAIIPDPVVAPSIVPVLKDEVDRKPEYPKPDTQQMIPFQPRHLAPPGLHPVPGGVFPVPPAAVVLMKLLPPPICFQGPFVQVDELMEIFRRCKIPNTVEEAVR--IITGGAPELAVEGNGPVESN----------AVLTKAVKRPNEDSDEDEEKGAVVPPVHDIYRARQQKRIR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25991-1", "uniprot_id": "SUF_DROME", "id": "P25991-1", "name": "Protein suppressor of forked", "aln": "---------MSSARDLIKVDIEWGMERLVRAQQVVELRPYDIESWSVMIREAQTRP-IHEVRSLYESLVNVFPTTARYWKLYIEMEMRSRYYERVEKLFQRCLVKILN---IDLWKLYLTYVKETKSGLSTHKEK---MAQAYDFALEKIG-MDLHSFSIWQDYIYFLRGVEAVGNYAENQKITAVRRVYQKAVVTPIVGIEQLWKDYIAFEQNINPIISEKMSLERSKDYMNARRVAKELEYHTKGLNRNLPA---------VP-PTLTKEEVKQVELWKRFITYEKSNPLRTEDTALVTRRVMFATEQCLLVLTHHPAVWHQASQFLDTSAR--------VLTEKGVRTSVENISPILCVPVVNQIEWVMAFAWWWAKDVQAAKIFADECANILERSINGVLNRNALLYFAYADFEEGRLKYEKVHTMYN-KLLQLPDIDPTLVYVQYMKFARRAEGIKSARSIFKKAREDVRSR-YHIFVAAALMEYYCSKDKEIAFRIFELGLKRFGGSPEYVMCYIDYLSHLNEDNNTRVLFERVLSSGGLSPHKSVEVWNRFLEFESNIGDLSSIVKVERRRSAVFENLKEYEGKETAQLVDRYKFLDLYPCTSTELKSIGYAENVGIILNKVGGG--AQSQNTGEVETDSEATPPLPRPDFSQMIPFKPRPCAHPGAHPLAGGVFPQPPALAALCATLPPPNSFRGPFVSVELLFDIFMRLNLPDSAPQPNGDNELSPKIFDLAKSVHWIVDTSTYTGVQHSVTAVPPRRRRLLPGGDDSDDELQTAVPPSHDIYRLRQLKRFAKSN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25298-1", "uniprot_id": "RNA14_YEAST", "id": "P25298-1", "name": "mRNA 3'-end-processing protein RNA14", "aln": "MSSSTTPDLLYPSADKVAEPSDNIHGDELRLRERIKDNPTNILSYFQLIQYLETQESYAKVREVYEQFHNTFPFYSPAWTLQLKGELARDEFETVEKILAQCLSGKLENNDLSLWSTYLDYIRRKNNLITGGQEARAVIVKAFQLVMQKCAIFEPKSSSFWNEYLNFLEQWKPFNKWEEQQRIDMLREFYKKMLCVPFDNLEKMWNRYTQWEQEINSLTARKFIGELSAEYMKARSLYQEWLNVTNGLKRASPINLRTANKKNIPQPGTSDSNIQQLQIWLNWIKWERENKLMLS-EDMLSQRISYVYKQGIQYMIFSAEMWYDYSMYISENSDRQNILYTALLANPD------------------------------SPSLTFKLSECYELDNDSESVSNCFDKCTQTLLSQYKKIASDVNSGEDNNTEYEQELLYKQREKLTFVFCVYMNTMKRISGLSAARTVFGKCRKLKRILTHDVYVENAYLEFQNQNDYKTAFKVLELGLKYFQNDGVYINKYLDFLIFLNKDSQIKTLFETSVEK-VQDLTQLKEIYKKMISYESKFGNLNNVYSLEKRFFERFP-----QENLIEVFTSRYQIQNSNLIKKLELTYMYNEEED--------------SYFSSGNGDGHHGSYNMSSSDRKRLMEETGNNGNFSNKKFKRDSELP--TEVLDLLSVIPKRQYFNTNLLDAQKLVNFLNDQVEIPTVESTKSG--------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : : .: :: .* :: :: :*: :.: :.*. ** : ** . *.* :: *: :: ***:: :** *. :.**. ** *::..:. :. :* :.:*:::.::* . :: * .:* :*: **. :....: *:*:* :*..*:: *: .:*::*. * :*: ** :.*: : * :**:** : :* :**.* * :* * : .: :*:::* .:* :*:.* * . ::::*: :. :* : : . . :*:: : ::. .: :*:: . .: . * * * . . : . * * . .. . *. :: *: .** . *:*: **: :* .*:.:.* :* *.*: * :.::* * :*: .:* . **:::***** : . *: *:*:* .**:*.: :.*** : . : *:: ::: :**::*:* .: .:*:* * : : :..**:: : . **. : : . . . . .* .::: . .. : .. :* . * :* *. ::..: *.::: :. .. ", "identical_positions": 123, "similar_positions": 245, "identity": "15.3%" }, { "cls_id": "homologset.agr.SGD:S000004671", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZMJ8-1", "uniprot_id": "A0A8I5ZMJ8_RAT", "id": "A0A8I5ZMJ8-1", "name": "Tether containing UBX domain for GLUT4", "aln": "MAAPAGGGGSAVSVLAPNGRRHTVKVTPSTVLLQVLEDTCRRQDFNPS--EYDLKFQRTVLDLSLQWRFANLPNNAKLEMVPAS--------RSREGPENTVRIALQLDDGCRLQDSFCSRQTLWELLNHFAQTRERLQQLGERTPVCVYMRDEVTGRAALQNTTLQSLGLTGGSATIRFVIKQYDTTGKQESIAVRSKPPGSPVSSMSADQASSSPLLPLNSGEFSRGDLNHQGGASTSGTSLKGGPKPADAQTKQSTTKESASAPFIPFSGGGQRLGGPSVSLRSLTSPAAKSSTSFSGPGGPSKPKKSKPGEEPPQEPEP-------------------PVDRDPVVCHPDLEDLLQPWPAEVPDEFFEVTVDDVRRRLAQLKSERKRLEEAPLVTKAFREAQMK---EKLERYPKVALRVLFPDRYILQGFFRPSETVGDLRDFVRSHLGNPELSFYLFIAPPKMVLDDHTLTLFQANLFP--AALVHFGAEEPTGLYLEPGLLEHTVSPSTADVLVASQQEVRATSLEMSIINHRTHPHPPRAGIKSRASLKTLRFLFSCKKRPPGFPLAQSHSLLPKEPWEFGWTTECSVFEKLRYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VBT9-1", "uniprot_id": "ASPC1_MOUSE", "id": "Q8VBT9-1", "name": "Tether containing UBX domain for GLUT4", "aln": "MAAPAGGGGSAVSVLAPNGRRHTVKVTPSTVLLQVLEDTCRRQDFNPS--EYDLKFQRTVLDLSLQWRFANLPNNAKLEMVPVS--------RSREGPENIVRIAFQLDDGSRLQDAFCSRQTLWELLSHFAQTRERLQQLGEKTPVCVYMRNEVTGRAALQNTTLQSLGLTGGSATIRFVIKQCDTAGKQESIAVRSKAPGSPVSSLSADQASSSTLLPLNSGEFSRGDLNHEGDANTSGTGLEGGPKPTDAQTKQSTS-EPASAPFVPFSGGGQRLGGPSASLRPLTSPSANSSKSFSGPGGPSKPKKPKPGEEPQQEPEP-------------------PVDRDPVVYHPDLEDLLQPWPAEVPDEFFEVTVDDVRRRLAQLKSERKRLEEAPLVTKAFREAQMK---EKLERYPKVALRVLFPDRYILQGFFRPSETVGDLRDFVRSHLGNPELSFYLFIAPPKMVLDDHTLTLFQANLFP--AALVHFGAEEPTGLYLEPGLLEHTVSPSTADVLVAR-------------CMSRASGSPPLLPAPDPVSLESEPIAEDGALGPP-EPIQGTAQPVKR---SLGKVPKWLKLPASKR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZE9-1", "uniprot_id": "ASPC1_HUMAN", "id": "Q9BZE9-1", "name": "Tether containing UBX domain for GLUT4", "aln": "MAAPAGGGGSAVSVLAPNGRRHTVKVTPSTVLLQVLEDTCRRQDFNPC--EYDLKFQRSVLDLSLQWRFANLPNNAKLEMVPAS--------RSREGPENMVRIALQLDDGSRLQDSFCSGQTLWELLSHFPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSATIRFVMKCYDPVG---------KTPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTS------GPCCEHTQEKQSTR-APAAAPFVPFSGGGQRLGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKSGQDPQQEQEQERERDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFELTVDDVRRRLAQLKSERKRLEEAPLVTKAFREAQIK---EKLERYPKVALRVLFPDRYVLQGFFRPSETVGDLRDFVRSHLGNPELSFYLFITPPKTVLDDHTQTLFQANLFP--AALVHLGAEEPAGVYLEPGLLEHAISPSAADVLVAR-------------YMSRAAGSPSPLPAPDPAP-KSEPAAEEGALVPP-EPIPGTAQPVKR---SLGKVPKWLKLPASKR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54730-1", "uniprot_id": "UBX4_YEAST", "id": "P54730-1", "name": "UBX domain-containing protein 4", "aln": "---------MPMVTVKYNFQLFKCKVSLNSTLNDVLHQSIQFFQLHTSSNDWSLIHLDKPVPLDLPWRLLNLPTGVNLELSKSSNFPVANKTNREDIPFNTIKIRFQIPGRDSVVKEMPSDQPIAPILRQMSG------AAGDDFKIQVFSKIIEFKTIKDENLTLENLGIQE-PSSVRLIFNN---------------------TSHSEGISANSAIHPKQT---------------------------------------------------------PPTMTNPETVASLP-------PHELHKPSVFLPSDEP------------------------------LAVIKDQIED----------EEDYELTVEQAKKYQKMLSSKAGTLGG-PILTKRLREQSANNLPKKNKAISECLLRVKFPDRSHIQIAFKPNEDMRTVYNVVSQFLIDENMPFTLNQSHPFKPLAKDDKKLLDDLEFGSKTMLLFETNSNSNGPLIKAHLLEDAQKITHETRTTPS----------------------------------VNTINKSNPQGPS-----DNATSIKK---TLNRVPKWMKLSKK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .: * : .. **: .:.* :**.:: : :::.. ::.* . . : *.* **: ***...:**: * . .: * * ::* :*: . : . : * *.: :* ::. * : *: : .. **:.**: .:::*:::: :* * . :: *. * :: *. .. * .: * **. ..::* .* : ::*: :* :*:**::.:: *.*: * *::** :** . : :* : .: *** **** :* *:*.* : : :.* ..* : ::.* * : * * .. .*:: * : *:. .:. * ::. ***.: . : .. . *. . : : :. ..: : ", "identical_positions": 81, "similar_positions": 153, "identity": "13.43%" }, { "cls_id": "homologset.agr.SGD:S000004673", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZQ5-1", "uniprot_id": "D3ZZQ5_RAT", "id": "D3ZZQ5-1", "name": "N-alpha-acetyltransferase 40", "aln": "-----MGRKSSKAKEKKQKRLEERAAMDAVCAKVDAANRLGDPLEAFPVFKKYDRNG--------------------------LNVSIECKRVSGLEPATVDWAFDLTKTNMQTMYEQSE---WG----WKDREKREEMTDDRAWYLIAWENNSIPVAFSHFRFDVECG-----------DEVLYCYEVQLESKVRRKGLGKFLIQILQLMANSTQMK-------KVMLTVFKHNHGAYQFFREALQFDIDDS----SPSMSGCCGEDCSYEILSRRTKFGDSQHSHTGGHCGGCCH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VE10-1", "uniprot_id": "NAA40_MOUSE", "id": "Q8VE10-1", "name": "N-alpha-acetyltransferase 40", "aln": "-----MGRKSSKAKEKKQKRLEERAAMDAVCAKVDAANRLGDPLEAFPVFKKYDRNG--------------------------LNVSIECKRVSGLEPATVDWAFDLTKTNMQTMYEQSE---WG----WKDREKREEMTDDRAWYLIAWENSSIPVAFSHFRFDVECG-----------DEVLYCYEVQLESKVRRKGLGKFLIQILQLMANSTQMK-------KVMLTVFKHNHGAYQFFREALQFEIDDS----SPSMSGCCGEDCSYEILSRRTKFGDSQHSHTGGHCGGCCH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86UY6-1", "uniprot_id": "NAA40_HUMAN", "id": "Q86UY6-1", "name": "N-alpha-acetyltransferase 40", "aln": "-----MGRKSSKAKEKKQKRLEERAAMDAVCAKVDAANRLGDPLEAFPVFKKYDRNG--------------------------LNVSIECKRVSGLEPATVDWAFDLTKTNMQTMYEQSE---WG----WKDREKREEMTDDRAWYLIAWENSSVPVAFSHFRFDVECG-----------DEVLYCYEVQLESKVRRKGLGKFLIQILQLMANSTQMK-------KVMLTVFKHNHGAYQFFREALQFEIDDS----SPSMSGCCGEDCSYEILSRRTKFGDSHHSHAGGHCGGCCH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q568K5-1", "uniprot_id": "NAA40_DANRE", "id": "Q568K5-1", "name": "N-alpha-acetyltransferase 40", "aln": "-----MGRKSNRAKEKKQRRLEERAAMDAVCAKVDAANKLEDPLSAMPVFKKYDRNG--------------------------LNLQIECKRVTALSPDTVEWAYELTRANMQTLYEQSE---WG----WKEREKREEMKDERAWYLLARDADSTPLAFSHFRFDVECG-----------DEVLYCYEVQLESKVRRKGLGKFLIQILQLIANSTQMK-------KVMLTVFKHNHGAYQFFREALQFEIDET----SPSMSGCCGEDCSYEILSRRTKYGEVSGHAHGGHCGGCCH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAI4-1", "uniprot_id": "Q9VAI4_DROME", "id": "Q9VAI4-1", "name": "N-alpha-acetyltransferase 40", "aln": "-----MRNQDDLSQGAKQR-------------FVETAARAKNPLESLSYQSYKAPSG--------------------------EEFKLICRAKSDADSKLLKWAFKLAETNVGPYYKQLK---MG----WQPKIKAAELNKNWARYLVAQNEKKENVAYAMFRFDMDHG-----------DCVLYCYEMQVAAEYRRKGLGKFIMSTLEDCARLWHLE-------KVMLTVLNNNEASISFFKQ-LGYVKDEI----SPDVL----EQADYQIFSKSMLS-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04751-1", "uniprot_id": "NAA40_YEAST", "id": "Q04751-1", "name": "N-alpha-acetyltransferase 40", "aln": "MRSSVYSENTYNCIRTSKEHLTERRRVAMAPMFQHFLNLCVEKFPESIEHKDTDGNGNFTTAILEREIIYIPEDDTDSIDSVDSLKCINYKLHKSRGDQVLDACVQLIDKHLGAKYRRASRIMYGNRKPWKAN-KLAEMKSAGLVYVCYWDNG-VLGAFTSFMLTEETGLVEGDALHEVSVPVIYLYEVHVASAHRGHGIGRRLLEHALCDGVARHTRRMCDNFFGVALTVFSDNTRARRLYEALGFYRAPGSPAPASPTIRHTRHGGGRVVVPCDPLYYVYCLHMP----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . .:. . : : . .* : : . :. . .* :: . *.: . * *: . * *:.. *: : *:: * : : * *:* **::: : * :*:*: ::. . : . * ***:..* : ::. : ** : : . ", "identical_positions": 25, "similar_positions": 60, "identity": "8.42%" }, { "cls_id": "homologset.agr.SGD:S000004676", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q06943-1", "uniprot_id": "HMGZ_DROME", "id": "Q06943-1", "name": "High mobility group protein Z", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGDRPKRPLSAYMLWLNETREQIKKDNPG--SKVTDIAKRGGELWRGLK--DKTEWEQKAIKMKEEYNKAVKEYEANGG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TDSGAPKK-------------------------------------RKKAAAKPAKKAKKKESSEEEEEDESE---------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05783-1", "uniprot_id": "HMGD_DROME", "id": "Q05783-1", "name": "High mobility group protein D", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MS-DKPKRPLSAYMLWLNSARESIKRENPG--IKVTEVAKRGGELWRAMK--DKSEWEAKAAKAKDDYDRAVKEFEANGGS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SAANGGGAKK-------------------------------------RAKPAKKVAKKSKKEES-DEDDDDESE---------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8I6A2H1-1", "uniprot_id": "A0A8I6A2H1_RAT", "id": "A0A8I6A2H1-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKCEDMAKADKARYEREMKTYIPHKGE------TKK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWTNTAADDKQPYGKMAAKLKEKYEKDIAAYRAK-GKP------DAAKKGVVKAEKSKKKKEE-------------------EDDEEDEEDEEEEEEKEDEDEEEE---------------DDDE----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63159-1", "uniprot_id": "HMGB1_RAT", "id": "P63159-1", "name": "High mobility group protein B1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGE------TKK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAK-GKP------DAAKKGVVKAEKSKKKKEE-------------------EDDEEDEEDEEEEEEEEDEDEEED---------------DDDE----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63158-1", "uniprot_id": "HMGB1_MOUSE", "id": "P63158-1", "name": "High mobility group protein B1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGE------TKK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAK-GKP------DAAKKGVVKAEKSKKKKEE-------------------EDDEEDEEDEEEEEEEEDEDEEED---------------DDDE----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GKR4-1", "uniprot_id": "A0A8I6GKR4_RAT", "id": "A0A8I6GKR4-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKGDPKKPRGKMSSYAFFVQTCREEHKRKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGE------TKK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAK-GKP------DAAKKGVVKAEKSKKKKEE-------------------EDDEEDEEDEEEEEEEEDEDEEED---------------DDDE----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09429-1", "uniprot_id": "HMGB1_HUMAN", "id": "P09429-1", "name": "High mobility group protein B1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGE------TKK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAK-GKP------DAAKKGVVKAEKSKKKKEE-------------------EEDEEDEEDEEEEEDEEDEDEEED---------------DDDE----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GJ73-1", "uniprot_id": "A0A8I6GJ73_RAT", "id": "A0A8I6GJ73-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGE------TKK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVVKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAK-GMQR-----KRGWSRLRRARKRRKRKTT-------------------RRMKRMRKRRKKMKMKMKKKMMMMNKLVLVGAQHKLVIYGDSSLVFGFFFLFLFLFFFLLVFFFHLQLSLMQLIRR-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "X1WFI9-1", "uniprot_id": "X1WFI9_DANRE", "id": "X1WFI9-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGK-DPRKPRGKMSSYAYFVQTCREEHKKKHPEASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKQDKVRYEREMKNYIPPKGE------KKK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RFKDPNAPKRPPSAFFIFCGDYRPKIKGENPGLSIGDIAKKLGEMWNSSSAEVKQPYEKKAAKLKEKYDKDIALYRTK-GIA--------GFS---------KKEGG-------------------EDDEEDEDDDEEEDDEEEEDDE-------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P30681-1", "uniprot_id": "HMGB2_MOUSE", "id": "P30681-1", "name": "High mobility group protein B2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDLAKSDKARYDREMKNYVPPKGD------KKG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KKKDPNAPKRPPSAFFLFCSENRPKIKIEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAK-GKS------EAGKKGPGRPTGSKKKNEP-------------------EDEEEEEEEEEEEDDEEEEEDEE------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52925-1", "uniprot_id": "HMGB2_RAT", "id": "P52925-1", "name": "High mobility group protein B2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDLAKSDKARYDREMKNYVPPKGD------KKG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAK-GKS------EVGKKGPGRPTGSKKKNEP-------------------EDEEEEEEEEDDEDEEEEDEDEE------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26583-1", "uniprot_id": "HMGB2_HUMAN", "id": "P26583-1", "name": "High mobility group protein B2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYVPPKGD------KKG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAK-GKS------EAGKKGPGRPTGSKKKNEP-------------------EDEEEEEEE-EDEDEEEEDEDEE------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZS25-1", "uniprot_id": "D3ZS25_RAT", "id": "D3ZS25-1", "name": "High mobility group protein B2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKGDPNKPRGKMSLYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDLAKSDKARYDREMKNYVPPKGN------KKG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAK-GKS------EVGKKGPGRPTGSKKKNEP-------------------EDEEEEEEE-DGEDEEEEDEDEE------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54879-1", "uniprot_id": "HMGB3_MOUSE", "id": "O54879-1", "name": "High mobility group protein B3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKGDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSSKEKSKFDEMAKADKVRYDREMKDYGPAKGG------KKK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLSDNEKQPYVTKAAKLKEKYEKDVADYKSK-GKF----------DGAKGPAKVARKKVE-------------------EEEEEEEEEEEEEEEEEDE----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15347-1", "uniprot_id": "HMGB3_HUMAN", "id": "O15347-1", "name": "High mobility group protein B3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKGDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEKSKFDEMAKADKVRYDREMKDYGPAKGG------KKK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQPYITKAAKLKEKYEKDVADYKSK-GKF----------DGAKGPAKVARKKVE-------------------EEDEEEEEEEEEEEEEEDE----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6ACD7-1", "uniprot_id": "A0A8I6ACD7_RAT", "id": "A0A8I6ACD7-1", "name": "High mobility group protein B3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKGDPKKPKGKMSAYAFFVQTCREEHKTKNPEVPVNFAEFSKKCSERWKTMSSKEKSKFDEMAKADKVRYGREMKDYESAKGG------KKK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KDPNAPKRPPSGFFLFCSEFRPKIKSANPGISIEDVVKKLGEMWNNLSDSEKQPYMTKAAKLKEKYEKDVADYKSN-GQF----------DGAKGPAKVARKTVE-------------------EEEEEKEEEEEEEQEDE------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1N808-1", "uniprot_id": "A0A8M1N808_DANRE", "id": "A0A8M1N808-1", "name": "High mobility group protein B2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGK-DPNKPRGKTSSYAFFVQTCREEHKKKNPGTSVNFSEFSKKCSERWRTMSSKEKGKFEEMAKTDKVRYDREMKNYVPPKGAK-----GGK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KKKDPNAPKRPPSAFFVFCSDHRPKVKGDNPGISIGDIAKKLGEMWSKLSPKEKSPYEQKAMKLKEKYEKDVAAYRAKGGKPD-----GAKKGGPGRPAGKKAEADD-------------------DDDEDEDEEDEEEEDEEDEDDDDE-----------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24537-1", "uniprot_id": "HMG2_DROME", "id": "Q24537-1", "name": "High mobility group protein DSP1", "aln": "MEHFHQIQQTIQHYQQQLAAQQQQQVQQQQLQQHQVVVQQNQQQAHQNSSNTTAGVGTQQLFTYKMASSFPNPATTMAQVVATSNAAGTTGYDYRLNMAQAAAAAAVPGSQWWYSAANQGQVDANTAAQLQHQQQQQQQQQQQQQQQHQQQQQMQQQQQQQNVINSASPMSRVKADAKPRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKDKQRYEAEMQNYVPPKGAVVGRGKKRK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QIKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGDIAKELGRKWSDVDPEVKQKYESMAERDKARYEREMTEYKTSGKIAMSAPSMQASMQAQAQKAALLAAAAQ-------------------QQHQQLEEQHDDDDGDGDDDENQ------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0ABK0L511-1", "uniprot_id": "A0ABK0L511_RAT", "id": "A0ABK0L511-1", "name": "High mobility group protein B4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKKVQLRPKVNVSSYIHFMINFRNKFKEQQPNTYLTFNEFSRRCSEKWRSISKNEKAKFEAIAKLDKARYQEEMMNYVGKRRK--------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RKRDPLAPRKPPSSFLLFSLDHFAKLKQENPNWTVVQVAKAAGKMWSMITDVDKRPYEQKAAIMRAKYFQEREAYLSQ------------------------CQNSK-------------------INLQGSSKSSLKE----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P8W9-1", "uniprot_id": "HMGB4_MOUSE", "id": "Q6P8W9-1", "name": "High mobility group protein B4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGEKDQLRPKVNVSSYIHFMLNFRNKFKEQQPNTYLGFKEFSRKCSEKWRSISKHEKAKYEALAELDKARYQQEMMNYIGKRRK--------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RKRDPKAPRKPPSSFLLFSRDHYAMLKQENPDWTVVQVAKAAGKMWSTTDEAEKKPYEQKAALMRAKYFEEQEAYRNQ------------------------CQGRK-------------------GNFLESAKTSLKQ----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JW93-1", "uniprot_id": "A0A0G2JW93_RAT", "id": "A0A0G2JW93-1", "name": "High mobility group protein B4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRE--------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQ------------------------CQRGE------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LC80-1", "uniprot_id": "A0ABK0LC80_RAT", "id": "A0ABK0LC80-1", "name": "High mobility group protein B4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYTGPRRE--------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQ------------------------CQRGK------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZLC5-1", "uniprot_id": "A0A8I5ZLC5_RAT", "id": "A0A8I5ZLC5-1", "name": "High mobility group protein B4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKDSKVRPKVNVSPYVHFMMDFRNQMREQQPNIYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYTGPRRE--------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RRRDADAPRKPPSSFLLFSQDHFEEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQ------------------------CQRGE------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LY90-1", "uniprot_id": "A0ABK0LY90_RAT", "id": "A0ABK0LY90-1", "name": "High mobility group protein B4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKDSKVRPKVNVSPYVHFMMDFRNQMREQQPNIYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRE--------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RRRDPDAPRKPPSSFLLFSQDHFEEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYQQ------------------------CQRGK------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P25976-1", "uniprot_id": "UBF1_MOUSE", "id": "P25976-1", "name": "Nucleolar transcription factor 1", "aln": "------------------------------------------------------------------MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCKLKWVEISNEVRKFRTLTELILDAQ-EHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPE--MSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKTLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQTTSPASKKPSQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLTEKKKAKYKAREAALKAQSERKPGGEREDRGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLS-NGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQRQYKVHLDLWVKSLSPQDRAAYKEYIS--NKRKNMTKLRGPNPKSSRTTLQSKSESEEDDDEEEEDDEEEEEEEEDDENGDSSEDGGDSSESSSEDESEDGDENDDDDDDEDDEDDDDEDEDNESEGSSSSSSSSGDSSDSGSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17480-1", "uniprot_id": "UBF1_HUMAN", "id": "P17480-1", "name": "Nucleolar transcription factor 1", "aln": "------------------------------------------------------------------MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCKLKWVEISNEVRKFRTLTELILDAQ-EHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPE--MSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLS-NGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYIS--NKRKSMTKLRGPNPKSSRTTLQSKSESEEDD-EEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3USZ2-1", "uniprot_id": "UBFL1_MOUSE", "id": "Q3USZ2-1", "name": "Upstream-binding factor 1-like protein 1", "aln": "------------------------------------------------------------------------------MTSLDNQGLWSEKDILKLLECMEHNIPSDDSREFKKSQADLNWSKVAFGLFSGEMCKQKWMEISYNLRKFRTLTELVQEAKFSFTKKTHKNKILTEHPDRPKRPLTAYLRFYKEQRAKYCQMYPK--YSNAQLTKILAEKYRQLPAEIKQRYIMDFKKEKEDFQKKMRQFKKRHP-VSGHPKKSVVPQS-------------------------------------------------------------------------------------------------HPTKVPTKSQ--------GDIKNVKS--------------------------------------------------------------------------------------------------------------------------------------------LVKTESPR--------------------------------------------------------------------------------------TVSSDMKFQGEPRKPPMNAYHKFHQESWS-SPELRHLSFRKRWVEISRRWHQVPENEKEHYSNQVKRLQKQYRVKLDLWLKRLSPEEYAAYKEAKATCGKRKNMSMSGGRSSKFGRTEQSSS--------EKGLQIKPGEVEELLDPGTDSS---------GTIQGHHDGAQSSRQDFTDDSEEDDS---------STSSDSSSTDEDD----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02486-1", "uniprot_id": "ABF2_YEAST", "id": "Q02486-1", "name": "ARS-binding factor 2, mitochondrial", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MNSYSLLTRSFHESSKPLFNLASTLLKASKRTQLRNELIKQGPKRPTSAYFLYLQDHRSQFVKENPT--LRPAEISKIAGEKWQNLEADIKEKYISERKKLYSEYQKAKKEFD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKLPPKKPAGPFIKYANEVRSQVFAQHPDKSQLDLMKIIGDKWQSLDQSIKDKYIQEYKKAIQEYNARYPLN--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q86BR8-1", "uniprot_id": "Q86BR8_DROME", "id": "Q86BR8-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------MIYTTTLMSSRGGLIGSLINKVRQVVAKDWPPSDPSRANDTDHRPLTPPRPLAAASISNTPAVPSKTLEEQLGLPPRPKKPLTPYFRFMREQRPKLKAANPQ--ITTVEVVRQLSKNWSDADAQLKERLQAEFKRDQQIYVEERTKYDATLTEEQRAEIKQLKQDLVDAKER--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RQLRKRVKELGRPKKPASAFLRFIASERIN-TPQGDKQTYREWHQKTTAKWTRLSDSEKEVYMQESRKEMELYRKAISVWEEKMIRLG---------------HIDVVRHGN------------------LIDPPEPKPRKTLASKDI------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : * . * :. : .: : * . : : .:: * ", "identical_positions": 5, "similar_positions": 15, "identity": "0.6%" }, { "cls_id": "homologset.agr.SGD:S000004677", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TDX8-4", "uniprot_id": "NB5R4_MOUSE", "id": "Q3TDX8-4", "name": "Cytochrome b5 reductase 4", "aln": "-------------------------------MLNVPSQAFPAPGSQQRVSSQG--RSKVPLKQGRSLMDWIRLTKSGKDLTGLKGGLIEVTEEELKKHNKKEDCWICIRGFVYNVSPYMEYHPGGEDELMRAAGADGTDLFNEVHRWVNYESMLKECLVGRMAVKP--AVPKDCHEG-KRVLNGMLPKSQMSDTLPRDVTDTLPREDLSSPSYDWFQTESSVTIVVYTKQKNISLDSVIVDLQDDSLRAEAVIKDHSYLVHVGLSHEVQEN-FSVRVIENVGKIEIVLQKKESVSWQCLGDHLEKHDSFIPKKDTGLYYRRCQLISKEDVTHDTRLFCLMLP-PSTHLQVPVGQHVYLKLSVTGAEIVKPYTPVSDSLLSDFKEPVLSPNKYICFLIKIYPAGLFTPELDRLQIGDFISVSGPEGDFKVSKLQEVEDLFLLAAGTGFTPMVTVLNYALSHMS-SLRKVKLMFFNKTEDDIIWRCQLEKLALREKRFDVEFVLSAPSPEWNGKQGHISRALLSEFLQRSSENSRAFLCICGPTPFTDEGIRLLHDLNFSDDEIHGFTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68EJ0-1", "uniprot_id": "NB5R4_RAT", "id": "Q68EJ0-1", "name": "Cytochrome b5 reductase 4", "aln": "-------------------------------MLNVPSQAFPAPGSQQRVASQG--RSKVPLKQGRSLMDWFRLTKSGKDFTGLKGGLIEVTEEELKKHNKKDDCWICIRGFVYNVSPYMEYHPGGEDELMRAAGADGTDLFNEVHRWVNYESMLKECLVGRMAVKP--AVPKDCHEG-KRVLNGMLPKSQ--------VTDTLPREGPSSPSYDWFQTESSVTIVIYTKQKNINLDSVIVDLQDDSLRAEAVIKDHSYLIHIGLSHEVQEN-FSVRVIENVGKIEIVLQKKETVSWKCLGDPLEKHDSFIPKKDTGLYYRQCQLISKEDVTHDTRLFCLMLP-PSTHLQVPVGQHVYLKLSVTGAEIVKPYTPVSESLLSDFKEPVLSPNKYIYFLIKIYPAGLFTPELDRLQIGDFVSVSGPEGNFKVSKLQEVEDLFLLAAGTGFTPMVTVLNHALTHMS-SLRKVKLMFFNKTEDDIIWRCQLEKLALKDKRFHVEYVLSAPSPEWNGKQGHVSRALLSEFLQRSLENSKVFLCICGPTPFTDEGIRLLHDLNFSDDEIHGFTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7L1T6-1", "uniprot_id": "NB5R4_HUMAN", "id": "Q7L1T6-1", "name": "Cytochrome b5 reductase 4", "aln": "-------------------------------MLNVPSQSFPAPRSQQRVASGG--RSKVPLKQGRSLMDWIRLTKSGKDLTGLKGRLIEVTEEELKKHNKKDDCWICIRGFVYNVSPYMEYHPGGEDELMRAAGSDGTELFDQVHRWVNYESMLKECLVGRMAIKP--AVLKDYREEEKKVLNGMLPKSQ--------VTDTLAKEGPSYPSYDWFQTDSLVTIAIYTKQKDINLDSIIVDHQNDSFRAETIIKDCLYLIHIGLSHEVQED-FSVRVVESVGKIEIVLQKKENTSWDFLGHPLKNHNSLIPRKDTGLYYRKCQLISKEDVTHDTRLFCLMLP-PSTHLQVPIGQHVYLKLPITGTEIVKPYTPVSGSLLSEFKEPVLPNNKYIYFLIKIYPTGLFTPELDRLQIGDFVSVSSPEGNFKISKFQELEDLFLLAAGTGFTPMVKILNYALTDIP-SLRKVKLMFFNKTEDDIIWRSQLEKLAFKDKRLDVEFVLSAPISEWNGKQGHISPALLSEFLKRNLDKSKVLVCICGPVPFTEQGVRLLHDLNFSKNEIHSFTA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q502I6-1", "uniprot_id": "NB5R4_DANRE", "id": "Q502I6-1", "name": "Cytochrome b5 reductase 4", "aln": "-------------------------------MLNVPSQAFPAAGSQQRVAPAGQSRNKVVLKPGHSLLDWIRLTKSGQDLTGLRGRLIEVTEDELKKHNTKKDCWTCIRGMVYNLSAYMDFHPGGEEELMRAAGIDSTDLFDEVHRWVNYESMLKECLVGRMAVKPSPALQAHTEKTESTHLNGLSAPPSLR---PEPLSAPLPAKDHR-PRYDWFQTDGTVNIVVYTKRKIPSAGCAVVDLQDDNLRVEMLLGRMSYLLYWRLSSRVQDH-VDVQTAHSVGKVQLCLRKSVKEKWTQLGQSLEHHDTFIQCKDRGLFYRECVLLSKTDVTHNTQLLRLQLP-RGSRMQVPVGRHVYLKTSVQGTDVVKPYTAVDQMLIPPSQSSAEVG-SDIHLMIKVYPDGVLTPHIANLPIGASLSVGGPEGSFTLRVLRDVTHLYMLAAGTGFTPMARLIRLALQDFT-VIRKMKLMFFNRQERDILWQSQLDELCTKEERFEVQHVLSEPADSWTGRRGRIDACMLQNFLERP-ENSKCLVCVCGPAGFTESAVQLVRQLDFSEEELHVFQA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZBK6-1", "uniprot_id": "A1ZBK6_DROME", "id": "A1ZBK6-1", "name": "", "aln": "MSDPSLKPPASNQPLRPPQLMAPAGSGGGLQLPVTAPQKLNSNGSSASGSATGNPRNKCALKPGYSLMNWIRLCNSGADLSGTGGRLVPVSRTELARHNKIDDAWMAIRGRVFNVTRYMDFHPGGVDELMRGVGRDATKLFDEVHAWVNYPQLLGKCYVGPLKDNE-----TKPAKESPQITNVILQPPE------------------IVPRFDWIQQRSELTLIFYTR-SLANPGLVVRRKDLQQLSVRVLVQHNWHSFDFQLTNNVEWPPKLAKIGSETGKIELVFVKEEAEPWPTYGTHVSNRLDSSRLHDETFEY---EVVHSKDFNHDSFELCLQSVGQKVLMVLPAGYHVDIEVPLEGRVIQRSYTPVDHTYLR-LENIRSSRSECLHFLIKRYPNGPVSSHLQKLETGSRVHWSAPRGSFQLSDLTAHRNILLLAAGSGLTPILSLIQPILKRNTNRIESLQLLYFNKTNEDIWLKEKLHELHTDDERFSCTNYVSQSED----NPQRIALELLAPLFQKNQPERCTYVLICGPSGFNTAALDILSQLDVKANQIHVFRG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04772-1", "uniprot_id": "IRC21_YEAST", "id": "Q04772-1", "name": "Increased recombination centers protein 21", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSDGMNRDVSNSKPNVRFAAPQRLSVAHPAISSPLHMPMSKSSRK----------------------------PLVRTKIRLDPGHSALDWHSLTSNPANYYTKFVSLQLIQDLLDDPVFQKDNFKFSPSQLKNQLLVQKIPLYKIMPPLRIN---RKIVKKHCKGEDELWCVINGKVYD-----ISSYLKFHP---GGTDILIKHRNSDDLITYFNKYHQWVNYEKLLQVCFIG---------------------------------VVCE---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . ::.: : . : : : : * . .: . . *. : . . : : . . .: : . .: .: : *. : * . .:: :: . *: : . ::: :. :* ", "identical_positions": 6, "similar_positions": 53, "identity": "1.06%" }, { "cls_id": "homologset.agr.SGD:S000004678", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADF5-1", "uniprot_id": "D4ADF5_RAT", "id": "D4ADF5-1", "name": "Programmed cell death protein 5", "aln": "MADEELEALRKQRLAELQAKHGDPGDAAQQEAKQR----EAEMRNSILAQVLDQSARARLSNLALVKPEKTKAVENYLIQMARYGQLSGKVSEQGLIEILEKVSQQT-EKKTT-------------VKFNRRK-VMDSDEDD-DY--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56812-1", "uniprot_id": "PDCD5_MOUSE", "id": "P56812-1", "name": "Programmed cell death protein 5", "aln": "MADEELEALRKQRLAELQAKHGDPGDAAQQEAKQR----EAEMRNSILAQVLDQSARARLSNLALVKPEKTKAVENYLIQMARYGQLSGKVSEQGLIEILEKVSQQT-EKKTT-------------VKFNRRK-VMDSDEDDADY--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14737-1", "uniprot_id": "PDCD5_HUMAN", "id": "O14737-1", "name": "Programmed cell death protein 5", "aln": "MADEELEALRRQRLAELQAKHGDPGDAAQQEAKHR----EAEMRNSILAQVLDQSARARLSNLALVKPEKTKAVENYLIQMARYGQLSEKVSEQGLIEILKKVSQQT-EKTTT-------------VKFNRRK-VMDSDEDD-DY--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VUZ8-1", "uniprot_id": "Q9VUZ8_DROME", "id": "Q9VUZ8-1", "name": "", "aln": "MSDSDLDALRAQRMSQMQSQFGGGNDAEKQQAQQEQMRAQEEMKHSILSQVLDQQARARLNTLKVSKPEKAQMFENMVIRMAQMGQVRGKLDDAQFVSILESVNAQMPQSKSS-------------VKYDRRRAAIDSDDDE-DYGC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04773-1", "uniprot_id": "YMW4_YEAST", "id": "Q04773-1", "name": "Uncharacterized protein YMR074C", "aln": "-MDPELQAIREARLAQLKNNSGGTNGDRNSGANNGG-GENSAPVGAAIANFLEPQALERLSRVALVRRDRAQAVETYLKKLIATNNVTHKITEAEIVSILNGIAKQQNSQNNSKIIFERKDFSEDLNSFDKQNAKNDDDEDDDDFFD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :*:*:* *::::: : *. .. :. *:: : : :::.*: .* **. : : : :::: .*. : :: .:: *: : ::.**: : * ....: .::::. *.*:*: *: ", "identical_positions": 20, "similar_positions": 62, "identity": "13.61%" }, { "cls_id": "homologset.agr.SGD:S000004681", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6TRW4-1", "uniprot_id": "PDS5B_RAT", "id": "Q6TRW4-1", "name": "Sister chromatid cohesion protein PDS5 homolog B", "aln": "MAHSKTRTN----------DGKITYPPGVKEISDKIS-KEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLALHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDTKSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDLMSSIICEGDTVSQELLDTVLVNLVPAHKN--------LNKQAYDLAKALLKRTAQAIEPYITNFFNQVLMLGK-----TSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMFGAK-DSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVSIVTAAKKDILLVNDH--LLNFVRERTLDKRWRVRKEAMMGLAQIYK---KYALQSAAGKDAAKQICWVKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYLYATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIK-QPKTDAS--------VKAIFSKVMVITRNLPDPGKAQDFMKKFTQVLEDDEKIRKQLEALVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEMIKFLLER-----IAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTHPISFHSAETFESLLACLKMDDEKVAEAALQIFKNTG---SKIEEDFPHIRSALLPVLHHKSKKGPPRQAKYAIHCIHAIFSSKE--------------------TQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQFAAPLKSLVATFIVKDLLMNDRLPGKK----TTKLWVPDEEVSPETMVKIQ----AIKMMVRWLLGMKNNHSKS------GTSTLRLLTTILHSDGDLTEQG-----KISKPDMSRLRLAAGSAIVKLAQEPCYHEIITLEQYQLCALAINDECYQVRQVFAQKLHKGLSRLR----LPLEYMAICALCAKDPVKERRAHARQCLVKNITVRREYLKQHAAVS------EKLLSLLPEYVVPYTIHLLAHDPDYVK---VQDIEQLKDVKECLWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDTKMNEKLYTVCDVAMNIIMSKSTTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGK----PKTANVLGAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDST---EMDHSENEDYTMSSPLPGKKSDKREDSDLVRSELEKPRSRKKASVTDPEEKLGMDDLSKLVQEQKPKGSQRGRKRGHAASESEEQQWPEEKRHKEELLGNEDEQNSPPKKGKRGRPPKPLGG-TSKEEPVVKTSKKGNKKKPAPPVVDEDEEEERQMGNTEQKSKSKQQRTSKRAQQRAESPETSAVESTQSTPQKGRGRPSKTPSPSQPKKNIRVGRSKQVATKENDSSEEMDVLQASSPVSDDTTQEGAEEEDISAGNVRRRSSKRERR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4VA53-1", "uniprot_id": "PDS5B_MOUSE", "id": "Q4VA53-1", "name": "Sister chromatid cohesion protein PDS5 homolog B", "aln": "MAHSKTRTN----------DGKITYPPGVKEISDKIS-KEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLALHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDTKSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDLMSSIICEGDTVSQELLDTVLVNLVPAHKN--------LNKQAYDLAKALLKRTAQAIEPYITNFFNQVLMLGK-----TSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMFGAK-DSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVSIVTAAKKDILLVNDH--LLNFVRERTLDKRWRVRKEAMMGLAQIYK---KYSLQSAAGKDAAKQISWVKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYLYATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIK-QPKTDAS--------VKAIFSKVMVITRNLPDPGKAQDFMKKFTQVLEDDEKIRKQLEALVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEMIKFLLER-----IAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTHPISFHSAETFESLLACLKMDDEKVAEAALQIFKNTG---SKIEEDFPHIRSALLPVLHHKSKKGPPRQAKYAIHCIHAIFSSKE--------------------TQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQFAAPLKSLVATFIVKDLLMNDRLPGKK----TTKLWVPDEEVSPETMVKIQ----AIKMMVRWLLGMKNNHSKS------GTSTLRLLTTILHSDGDLTEQG-----KISKPDMSRLRLAAGSAIVKLAQEPCYHEIITLEQYQLCALAINDECYQVRQVFAQKLHKGLSRLR----LPLEYMAICALCAKDPVKERRAHARQCLVKNITVRREYLKQHAAVS------EKLLSLLPEYVVPYTIHLLAHDPDYVK---VQDIEQLKDVKECLWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDTKMNEKLYTVCDVAMNIIMSKSTTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGK----PKTANVLGAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSS---EMDHSENEDYTMSSPLPGKKSDKREDPDLS--ELEKPRSRKKAPVTDPEEKLGMDDLTKLVQEQKPKGSQRGRKRGRTASDSDEQQWPEEKRHKEELLENEDEQNSPPKKGKRGRPPKPLGGGTSKEEPTMKTSKKGNKKKLVPPVVDDDEEEERQIGNTEHKSKSKQHRTSKRAQQRAESPETSAVESTQSTPQKGRGRPSKAPSPSQPPKKIRVGRSKQVATKENDSSEEMDVLQASSPVSDDTTQEGAEEEDISVGNVRRRSSKRERR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NTI5-1", "uniprot_id": "PDS5B_HUMAN", "id": "Q9NTI5-1", "name": "Sister chromatid cohesion protein PDS5 homolog B", "aln": "MAHSKTRTN----------DGKITYPPGVKEISDKIS-KEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLALHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDTKSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDLMSSIICEGDTVSQELLDTVLVNLVPAHKN--------LNKQAYDLAKALLKRTAQAIEPYITNFFNQVLMLGK-----TSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMFGAK-DSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVSIVTAAKKDILLVNDH--LLNFVRERTLDKRWRVRKEAMMGLAQIYK---KYALQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYLYATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIK-QPKTDAS--------VKAIFSKVMVITRNLPDPGKAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEMIKFLLER-----IAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTHPISFHSAETFESLLACLKMDDEKVAEAALQIFKNTG---SKIEEDFPHIRSALLPVLHHKSKKGPPRQAKYAIHCIHAIFSSKE--------------------TQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQFAAPLKSLVATFIVKDLLMNDRLPGKK----TTKLWVPDEEVSPETMVKIQ----AIKMMVRWLLGMKNNHSKS------GTSTLRLLTTILHSDGDLTEQG-----KISKPDMSRLRLAAGSAIVKLAQEPCYHEIITLEQYQLCALAINDECYQVRQVFAQKLHKGLSRLR----LPLEYMAICALCAKDPVKERRAHARQCLVKNINVRREYLKQHAAVS------EKLLSLLPEYVVPYTIHLLAHDPDYVK---VQDIEQLKDVKECLWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKSTTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGK----PKTTNVLGAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSS---EMDHSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPV-DDIPQEETEEEEVSTVNVRRRSAKRERR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6A026-1", "uniprot_id": "PDS5A_MOUSE", "id": "Q6A026-1", "name": "Sister chromatid cohesion protein PDS5 homolog A", "aln": "MDFTQ-PKPATALCGVVSADGKIAYPPGVKEITDKIT-TDEMIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNTKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKN--------LNKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGR-----SSVSDLSEHVFDLIQELFAIDPQLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSK-DSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAAKRDLALVNDQ--LLGFVRERTLDKRWRVRKEAMMGLAQLYK---KYCLHGEAGKEAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHK-QPTSEAN--------CSAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADVCVREIARKLANPKQPTNPFLEMVKFLLER-----IAPVHIDSEAISALVKLMNKSIEGTADDEEEGVSPDSAIRSGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQIFRNTG---HKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFSNKE--------------------VQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRSTGEK----NGKLWSPDEEVSPEVLAKVY----LLRLLVRWLLGMKNNQSKS------ANSTLRLLSAMLVSEGDLTEQK-----RISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKALVKLL----LPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMAT------EKLLSLLPEYVVPYMIHLLAHDPDFTR---SQDVDQLRDIKECLWFMLEVLMTKNENNSHAFMKKMAENIKLTRDAQSPDESKTNEKLYTVCDVALCVINSKSALCNADSPKDPVLPMKFFTQPEKDFCNDKSYISEETRVLLLTGK----PKPTGVLGTVNKPLSATGRKPYVRSAGTETGSNINANSELSPSAGSRSREQSSEASETGVSENE--------------------------ENPVRIISVTPVKNIDTVKNKEINSDQSTQGNISSDRGKKRIVTAAGAENIQ-KPDEKV-------DESGPPAPSKPRRGRRPKSESQGNATKN----------------------DDLNKPVSK-----------GRKRAAGSQES-----LEAGN----------AKAPKLQDGAK-KAVPAERQIDLQR---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A4L9P7-1", "uniprot_id": "PDS5A_RAT", "id": "A4L9P7-1", "name": "Sister chromatid cohesion protein PDS5 homolog A", "aln": "MDFTQ-PKPATALCGVVSADGKIAYPPGVKEITDKIT-TDEMIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNKKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKN--------LNKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGR-----SSVSDLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSK-DSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAAKRDLALVNDQ--LLGFVRERTLDKRWRVRKEAMMGLAQLYK---KYCLHGEAGKEAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHK-QPTSEAN--------CSAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADICVREIARKLANPKQPTNPFLEMVKFLLER-----IAPVHIDSEAISALVKLMNKSIEGTADDEEEGVSPDSAIRSGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQIFRNTG---HKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFSNKE--------------------VQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRSTGEK----NGKLWSPDEEVSPEVLAKVQ----AIKLLVRWLLGMKNNQSKS------ANSTLRLLSAMLVSEGDLTEQK-----RISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKALVKLL----LPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMAT------EKLLSLLPEYVVPYMIHLLAHDPDFTR---SQDVDQLRDIKECLWFMLEVLMTKNENNSHAFMKKMAENIKLTRDAQSPDEAKTNEKLYTVCDVALCVINSKSALCNADSPKDPVLPMKFFTQPEKDFSNDKSYISEETRVLLLTGK----PKPTGVLGTVNKPLSATGRKPYVRSAGTETGSNINASSELSPSAGNRSREQSSEASETGVSENE--------------------------ENPVRIISVTPVKSIDTVKNKEINSDQSTQGNISSDRGKKRIVTAAGAENIQQKPDEKA-------DESGPPAPSKPRRGRRPKSESQGNATKN----------------------DDLSKPVSK-----------GRKRAAGSQES-----LEAGN----------AKAPKLQDGAK-KAVPAERQIDLQR---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q29RF7-1", "uniprot_id": "PDS5A_HUMAN", "id": "Q29RF7-1", "name": "Sister chromatid cohesion protein PDS5 homolog A", "aln": "MDFTAQPKPATALCGVVSADGKIAYPPGVKEITDKIT-TDEMIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNKKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKN--------LNKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGR-----SSVSDLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSK-DSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAAKRDLALVNDQ--LLGFVRERTLDKRWRVRKEAMMGLAQLYK---KYCLHGEAGKEAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHK-QPTSEAN--------CSAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADICVREIARKLANPKQPTNPFLEMVKFLLER-----IAPVHIDSEAISALVKLMNKSIEGTADDEEEGVSPDTAIRSGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQIFRNTG---HKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFTNKE--------------------VQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRSTGEK----NGKLWSPDEEVSPEVLAKVQ----AIKLLVRWLLGMKNNQSKS------ANSTLRLLSAMLVSEGDLTEQK-----RISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKALVKLL----LPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMAT------EKLLSLLPEYVVPYMIHLLAHDPDFTR---SQDVDQLRDIKECLWFMLEVLMTKNENNSHAFMKKMAENIKLTRDAQSPDESKTNEKLYTVCDVALCVINSKSALCNADSPKDPVLPMKFFTQPEKDFCNDKSYISEETRVLLLTGK----PKPAGVLGAVNKPLSATGRKPYVRSTGTETGSNINVNSELNPSTGNRSREQSSEAAETGVSENE--------------------------ENPVRIISVTPVKNIDPVKNKEINSDQATQGNISSDRGKKRTVTAAGAENIQQKTDEKV-------DESGPPAPSKPRRGRRPKSESQGNATKN----------------------DDLNKPINK-----------GRKRAAVGQESP--GGLEAGN----------AKAPKLQDLAK-KAAPAERQIDLQR---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L1F4-1", "uniprot_id": "PDS5A_DANRE", "id": "A1L1F4-1", "name": "Sister chromatid cohesion protein PDS5 homolog A", "aln": "MEFPQQPQQQRPAG-----DGKITYPLGVKEITDKIS-NDEVVKRLKLVVKTYMDMDQDSEEEKQQYLALALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKEIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFKTLFSVINNSHNQKVQMHMLDLMSSIIMEGDGVTQELLDTILINLIPAHKN--------LNKQAYDLARTLLKRTVQTIETCIASFFNQVLVMGK-----SSVSDLSEHVFDLIQELFAIDPLLLVSVMPQLEFKLKSNDGEERLAVVKLLAKLFGAK-DSELATQNRPLWQCFLGRFNDIHVPVRLECVKFASHCLMNHPDLAKDLTEFLKVRSHDPEEAIRHDVIVTIINAGKKDLNLVNDQ--LLGFVRERMLDKRWRVRKEAMMGLAQLFK---KYCLHHEAGKESALKISWIKDKLLHIYYQNSIDDKLLVEKIFAQYMVPHSLETEEKMKCLYYLYACLDTNAVKALNEMWKCQNMLRGLVRELLDLHK-LPTSEAN--------TSAMFGKLMTIAKNLPDPGKAQDFMKKFNQVLGEDEKLRLQLEQLISPTCSCKQAEQCVREITRKLTFPKQPTNPFLEMVKFLLER-----IAPVHIDSEAISALVKLLNKSIEGTADDEDEGVTPDTAIRAGLELLKVLSFTHPTAFHSAETYESLLQCLKMEDDKVAEAAIQIFRNTG---QKIETELPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFHNKE--------------------VQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSIVANFIVKDLLMNDRSVGNK----NGRLWTADDEVSPEVLAKVQ----AIKLLVRWLLGMKNNQSKS------ANSTLRLPSAMLVSEGDLTEQK-----KISKSDMSRLRLAAGSAILKLAQEPCYHDIITPEQFQLCGLVINDECYQVRQIYAQKLHVALVKLL----LPLEYMAVFALCAKDPVKERRAHARQCLLKNISVRREYIKQNPMAH------EKLLSLLPEYVVPYMIHLLAHDPDLTK---PQDLEQLRDVKECLWFMLEVLMTKNENNSHSFLRKMVENIKQTKDAQCPDDPKANEKLYIVCDVALFVIANKSTSCHLDSPKDPVLPSKFYTPPDKEFVNDKEYLSAEAKIVLQTGKIQQPPKQTGVLGAVNKPLTVTARRPYIKTFTSETGSNASTNSQPSSPATNKSRDVSS---EVGARENE--------------------------ENPVITKAVS------------VKKEEAAQ-----PSGRKRAAPAS--DGTENSVSSNP-------SAGSQPPLNKPRRGRPPKN-SAGAATQE----------------------KEAGATTGAGAG-------RGRKRAAPSQDPSSTASTDALS----------DKTPKQQKEAEPKRAAPQRQIDLQR---------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z8S6-1", "uniprot_id": "A1Z8S6_DROME", "id": "A1Z8S6-1", "name": "", "aln": "-------------------MADIVYPTGCRPLVEDLG-TDELIRRLKTLANVLQTMDQD-DNLYQQYIPLALHLLDDFFMQHPSRDVQLLIACCVADVLRVYAPEAPYKEQDQIKTIFKFFIKQLHGLKDPRDPSFKRYFYLLENLAFVKSFNMCFELEDCQEIFQDLFSTIFKIVNDQHSVKVTNFFLDVLSPLITEADNLSVELLDLILINIVEPYKS--------NNKFACQLTEQLLTKTGDALESTIKMFFNRALVMDKP----NTKLSITNKIYDIIYELNRINAGLLCSVLPQLENKLLSTDDAERLKATTLLSRMFSEK-DSQLAKKYPNLLKIFFGRFCDITEPVRIKCVQSSMHFLLNHPSLQHDITEKLRLRNHDLDEVVRHEVVMAIVETAKRDFTLVLEAPDLLEIVRERTLDKKYKIRRDAMNGLAYIYKR--AICEPNDLSTGLKVRVDWIKNKILHGYYKVGLEDRLLVERLLITCLVPYKLAPEERMKKLYHLLGDLDANATKAFVELQKNQMKTRNTVSDWIKLHHSKEFTPRV--------LSQLSAKQANIAKLLPDPLKAAEYLTQFSNNLRKDAQLLRCINIVLKRDVSCRECADTMGVLLKKLG-AHVQSNLYYNTVKMLIER-----VASVMVDKESIGVLISLIEQCIEKGSMCEEIGISAQEAGERGLKLLAMLSYVFSAHFFTDTSLRHLISLLSYEQDYVAPLVLKTLTHLGRYQPLIDDPTPAILDELAPVCKDFALIGTPKQAKHAVRCIFVNSQSSASTDGATSGAGSASTTTQTVHPIFNEIIETLRLKLTPN-CEHQRTKIVTLGHIAYNMPQAFLTPIKNMIARRIVKELLIQEVPAQRDYELPEDSDWCAQEKLPPDTLCKLD----ALKAMARWLLGLR-TDEHA------AQKTFRMLAAFVNQRGDLLGQN-----RLCGAEKSWLRLGAACAMLKVCEQKGVGDQYSAEQYLQLSQLMADPVPEVREIFARKLHKGLSRSLPRNCLPLDFMGLYVLAGLETERKLQDLVRHYAETDVNKRREYLKTVAMTSPDSSTESQSLHILPDYMLAFAIPVLVHDPRFTN---HEDYVQLRKMEKCLRFILEPLMAKRETFVHSFYKQLLQLIKHREFSLGSDK-RDNYKMWALCDLAMYIIDSKFSPFDGNTST--------FSMP---LALPEMYYKEPAVANFQNND-------------VYIPLDVYTLGAKSTSKAAATAMTTSRAAVAPKRPAEQSIMDDE-----NPQENN------------------------------------------------LFDNIRAADTTEPMAKRTRAGAASAKS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04264-1", "uniprot_id": "PDS5_YEAST", "id": "Q04264-1", "name": "Sister chromatid cohesion protein PDS5", "aln": "--------------MAKGAVTKLKFNSPIISTSDQLISTNELLDRLKALHEELASLDQDNTDLTG-LDKYRDALVSRKLLKHKDVGIRAFTACCLSDILRLYAPDAPYTD-AQLTDIFKLVLSQFEQLGDQENGYHIQQTYLITKLLEYRSIVLLADLPSSNNLLIELFHIFYDPN-KSFPARLFNVIGGILGEVISEFDSVPLEVLRLIFNKFLTYNPNEIPEGLNVTSDCGYEVSLILCDTYSNRMSRHLTKYYSEIIHEATNDDNNSRLLTVVVKLHKLVLRLWETVPELINAVIGFIYHELSSENELFRKEATKLIGQILTSYSDLNFVSTHSDTFKAWISKIADISPDVRVEWTESIPQIIATREDISKELNQALAKTFIDSDPRVRRTSVMIFNKVPVTEIWKNITNKAIYTSLLHLAREKHKEVRELCINTMAKFYSNSLNEIERTYQNKEIWEIIDTIPSTLYNLYYINDLNINEQVDSVIFEYLLPFEPDNDKRVHRLLTVLSHFDKKAFTSFFAFNARQIKISFAISKYIDFSKFLNNQESMSSSQGPIVMNKYNQTLQWLASGLSDSTKAIDALETIKQFN--DERIFYLLNACVTNDIPFLTFKNCYNELVSKLQTPGLFKKYNISTGASIMPRDIAKVIQILLFRASPIIYNVSNISVLLNLSNNSDAKQLDLKRRILDDISKVNPTLFKDQIRTLKTIIKDLDDPDAEKNDNLSLEEALKTLYKAS---KTLKDQVDFDDTFFFTKLYDFAVESKPEITKYATKLIALSPKAEET----------------------LKKIKIRILPLDLQKDKYFTSHIIVLMEIFKKFPHVLNDDSTDIISYLIKEVLLSNQVVGDSK----KEIDWVEDSLLSDTKYSAIGNKVFTLKLFTNKLRSIAPDVPRDELAESFTEKTMKLFFYLIASGGELISEFNKEFYPTPSNYQTKLRCVAGIQVLKLARISNLNNFIKPSDIIKLINLVEDESLPVRKTFLEQLKDYVANEL----ISIKFLPLVFFTAYEPDVELKTTTKIWINFTFGLKSFKKGT-----------------IFERALPRLIHAIAHHPDIVGGLDSEGDAYLNALTTAIDYLLFYFDSIAAQENFSLLYYLSERVKNYQDKLVEDEIDEEEGPQKEEAPKKHRPYGQKMYIIGELSQMILLNLKEKKNWQHSAYPGKLNLPSDLFKPFATVQ--------------EAQLSFKTYIPESLTEKIQNNIKAKIGRILHTSQTQRQRLQKRLLAHENNESQK--------------------------------------------KKKKVHHARSQADDEEGDGDRESDSDDDSYSPSNKNETKKG-------HENIVMKKLRVRKEVDYKDDEDDDIEMT-----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : :.: .:*:: *** : : :*** : * . :::: . .:: : ***::*::*:***:***.. ::. ** :. *:. * * .. . : **: :: :* : :* ..:::: :*: ::. . . :: : .::. :* * * :. *:* :: ::: . .. . ::: * : :. : ::.. : . : ::..:: .* . *: :*: : :* * : * .. *:.::: * ::.. : ::.:: ** :*:: .: : : .: .: :::.: * * : :*: :: : . :: : : . :*: .:*. .: :* ::. .. : : ..: : ** .:: . *: :: ::*.. :::: * : . :* :* .:: : * : . :.: : . . :: *.*. ** : : :.: * :: :: :. . : ** . .: . :: * : : . ..* :. :. :: : : . .:. : : . ::: .:: : : . :. : . . : . *. :* * : * . : :: * . : : :: : .* *. : ..::: * : ** :: . * :. :. : :: :.. * .: : .*::: :: . *:* : : ** *. ::*:.. : . .: : * **: : .:*: : . :.:.:: : : . :. : : .: . : : : :. * :.*.* . :. *. : .: ::* : : .:: : : :* . *. : .: : . . : : . * . : . . . : . . .:: : : . ", "identical_positions": 100, "similar_positions": 396, "identity": "6.44%" }, { "cls_id": "homologset.agr.SGD:S000004682", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96FZ7-1", "uniprot_id": "CHMP6_HUMAN", "id": "Q96FZ7-1", "name": "Charged multivesicular body protein 6", "aln": "MGNLFGR--KK--QSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDG-----RKERAKLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSIEEVERILDETQEAVEYQRQIDELLAGSFTQED--EDAILEELSAITQ-------EQIELPEVPSE---PLP-------------------------EKIPENVPVKARPRQAELVAAS-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0C0A3-1", "uniprot_id": "CHMP6_MOUSE", "id": "P0C0A3-1", "name": "Charged multivesicular body protein 6", "aln": "MGNLFGR--KK--QSRVTEQDRAILQLKQQRDKLRQYQKRVTQQLERERALARQLLRDG-----RKERAKLLLKKKRYREQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQVGNECLNKMHQVMSIEEVERILDETQEAVEYQRQIDELLAGNFTQED--EDAILEELNAITQ-------EQMELPEVPSE---PLP-------------------------DRNPE-APAKARSRQAELVAAS-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AQ75-1", "uniprot_id": "A0A8I6AQ75_RAT", "id": "A0A8I6AQ75-1", "name": "", "aln": "MGNLFGR--KK--QSRVTEQDRAILQLKQQRDKLRQYQKRVTQQLERERALARQLLRDG-----RKERAKLLLKKKRYREQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQVGNECLNKMHQVMSIEEVERILDETQEAVEYQRQIDELLAGSFTQED--EDAILEELNAITQ-------KPLPRPDPGRQSWWPLRNLQGLIGILRGLSHRAFGCESTLRAPRRPEGLDGPVQVPMAGAAAYTGADVRAPRCAI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q503V0-1", "uniprot_id": "CHMP6_DANRE", "id": "Q503V0-1", "name": "Charged multivesicular body protein 6", "aln": "MGNLFGK--KK--ATRVTEQDRAVLQLKQQRDKLKQYQKRITLQMDKERQLAKQLLKDG-----KKDKALLLLKKKRYQDQLLEKTENQISNLERMVQDIEFAQIEMKVIEGLKVGNDCLKKMHEVLSIEEVEKIMDETHDAIEYQKQIDEMLAGSLTQED--EEAVLAELEAITQGE-----ADLELPEVPGE---ELP--------------------------EVPEQEPVREKERVKKKPEREMVAV-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W236-1", "uniprot_id": "Q9W236_DROME", "id": "Q9W236-1", "name": "", "aln": "MGALFGKTSKKTAPSRITDQDKAVLQLKQQRDRLKQYQKRIETQLENDRLLARKCLQQG-----RKDRAKLLLRKKKYQESLLTNADKQLENLEKLAADIEFAQVEMKVLDGLKAGNAALKKVHEMLDIDEVERIMDETREGIEKQQEIDAILTDVLTTQD--EEDVLAELDALEAEEEQQ--KGAQLPDVPTED-LPIP--------------------------AEIESVEEPAKTKATKKVLVEA----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04272-1", "uniprot_id": "VPS20_YEAST", "id": "Q04272-1", "name": "Vacuolar protein sorting-associated protein 20", "aln": "MGQKSSK-------VHITKTDRAILEVKRSKDEIHKFTRRTDNLILVEKSQLKDLIRKNPENYKSNMKVRFLLKRIHYQEHLLQQASDQLINLENMVSTLEFKMVEKQFINGLKNGNEILKKLNKEFS--NVDELMDDVQDQIAYQNEINETLSRSLVGTSNYEDDLDKELDALESELNPEKMNNAKVANMPSTEGLPSLPQG--------------------EQTEQKEREEFATEERSDTKEPLALLS--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .: ::*. *:*:*::*:.:*.:::: :* : :: :. ::.. : :. :**:: :*:: ** .:..*: .** :. :** :* :.::**: ** *:*::: :. :*:.::*:.:: : *.:*: *: :. . *: : **.*: .: * . ", "identical_positions": 36, "similar_positions": 81, "identity": "13.95%" }, { "cls_id": "homologset.agr.SGD:S000004683", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AC99-1", "uniprot_id": "D4AC99_RAT", "id": "D4AC99-1", "name": "Chromosome transmission fidelity protein 18 homolog", "aln": "MEDYEEDLYGVEDDFQNQFAAELEVLAEL---EGTGDLAPSETLQTPASRPPLTFEEAIAGG-------DIVPRPCPAGSSGNDSRNTRKN-----VRRDQPAPSSPMVKR------PRLDVVKRLN----------FEPD-KEELLYPDSPPGDITPPPSPEVFPEMWDAGPSDAGADNGLMQALPSPRN--PVLRRPPVLEDYINVTSTCGER---AFLVLRADLTGTGVQNHLPDVQWRGRGQLDLLGVPFTSLKEQVDNKRRQQLLEEAQQLSDTLHSLRS-EGEEA---------MLEGPPEEEPGPGQETAQHCLWVDEFAPQHYTELLSDDFTNRCLLKWLKLWDLVVFGHERPARKPR---------PGVEPTRVGKEAPAPGKWKS----HEQVLEEMLEAELDPSRRPRQKVALLCGPPGLGKTTLAHVVARHAGYCVVEMNASDDRSPEAFRTRIEAATQMESVLGAGGRPNCLVIDEIDGAPTA-AINVLLSILNRKGPQEAEQGGTAVAAAGGRRRRAEGGLLTRPIICICNDQFTPSLRQLKQQALLLHVPPTLPSRLVQRLQEISLQHGMRSDPGALAALCEKTDNDIRACINTLQFLYGRGQRELSVKDVQTTHVGLKDQRKGLFSVWQEVFQLPRAQRRLVGQDLMLPTHALLLNDSDKGSLTLASQRFYHILRVTTSAGEHEKVVQGLFDNFLRLRLRDSSLGTVCCALDWLAFDDLLEQAAHHGQSFQLLRYLPFLPAAFHVLFASSHVP-RITFPSS---QQEAQTRLSQTRNHIQTLVSGMAPATRSRATPQALVLDTLCLLLDVLSPKLRPVSTQLYSAREKQQLSSLVGTMLAYSLTYHQERTPDGQYLYRLEPNVEEVCRFPELPARKPLTYQAKQLIAREIEMEKMWRAEALAWTGGGPQVDQGPSGPANLRTDSGEKGTRQPAPRNHEQRLEHIMKRAAVQEQVCCGGRGRVGLEQSDEQRVGLAPSPKEPPVAPRKWAVVSRRTPSHRPCSEASEPLTWERPGYACLSTGNLMTLFSASLRGTSLDVWSSGKWQSQAKRLRPPRRTRTSGAWVWQWAGVRCGSGSTRVSPMLFGAACTSGTCCSPTAPGHQIRLTPTGMYQGRDSWRSLFIKSHLNRECGSGSEDGTLGLLHPRVVLHQVRVQEGVLGDPVLNPLEEPVSGESQCWSFPWHLPTGV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BIW9-1", "uniprot_id": "CTF18_MOUSE", "id": "Q8BIW9-1", "name": "Chromosome transmission fidelity protein 18 homolog", "aln": "MEDYEEDLYGVEDDFQNQFAAELEVLAEL---EGTRDQAPPGTLQTPASRPPLTFEEAIAGG-------DTVPRPCPAGSPGNVNRNTRKN-----VRRDQPAPSSPMVKR------PRLDVVKKLN----------FEPD-MEELLYPDSPPGDITPPPSPEVFPEMLDAGYSDANADKDLMQTLPSPRNRNPVLRRPPILEDYINVTSTSGER---AFLVLRADLIGPGVQNPLLDVHWRGCGQLDLLGVPFASLKEQVDSKRRQQLLEDAQQLSDTLHSLRS-EGEEA---------VLEGPPAEEPAPGQNTAQHCLWVDEFAPQHYTELLSDDFTNRCLLKWLKLWDLVVFGRERPARKPR---------PGVETTRVGKEATAPGKWKS----HEQALEEMLEAELDPSQRPRQKVALLCGPPGLGKTTLAHVVARHAGYCVVEMNASDDRSPEAFRTRIEAATQMESVLGVGGRPNCLVIDEIDGAPTA-AINVLLGILNRKGPQEADQGGTAVAAGG-RRRRAEGGLLTRPIICICNDQFTPSLRQLKQQALLLHVPPTLPSRLVQRLQEISLQHGMRSDPGALVALCEKTDNDIRACINTLQFLYGRGRRELSVKAVQTTHVGLKDQRKGLFSVWQEVFQLPRTQRRIVGQDLMLPAHALLLSNGDKGSLTLASQRFYHILRVTTSAGEHEKVVQGLFDNFLRLRLRDSSLSTVCCALDWLAFDDLLEQAAHRGQSFQLLCYLPFVPAAFHVLFASSHVP-RITFPSS---QQEAQTRMSQTRNHIQTLVSGMAPTTRSRATPQALVLDTLCLLLDVLAPKLRPVSTQLYSAHEKQQLSCLVGTMLAYSLTYHQERTPDGQYLYKLEPNVEEVCRFPELPARKPLTYQAKQLIAREIEMEKMRRAEALAWARSGPQVDQGSSGPASLWTDSGEKGTRQPAPRNHEQRLEHIMKRATVQEQPERDFFGRV---------------------VIRKVAVPSR---------EVEAP-------------------------------------QKDADEWRMGVAVGRSEVWFRFNEGVSN-----------------------------AVR-------------RSLYIRDLL-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WVB6-1", "uniprot_id": "CTF18_HUMAN", "id": "Q8WVB6-1", "name": "Chromosome transmission fidelity protein 18 homolog", "aln": "MEDYEQELCGVEDDFHNQFAAELEVLAEL---EGASTPSPSGVPLFTAGRPPRTFEEALARG-------DAASSPAPAASVGSSQGGARKRQVDADLQPAGSLPHAPRIKR------PRLQVVKRLN----------FRSEEMEEPPPPDSSPTDITPPPSPEDLAELWGHGVSEAAADVGLTRASPAARN--PVLRRPPILEDYVHVTSTEGVR---AYLVLRADPMAPGVQGSLLHVPWRGGGQLDLLGVSLASLKKQVDGERRERLLQEAQKLSDTLHSLRSGEEEAA---------QPLGAPEEEPTDGQDASSHCLWVDEFAPRHYTELLSDDFTNRCLLKWLKLWDLVVFGHERPSRKPR---------PSVEPARVSKEATAPGKWKS----HEQVLEEMLEAGLDPSQRPKQKVALLCGPPGLGKTTLAHVIARHAGYSVVEMNASDDRSPEVFRTRIEAATQMESVLGAGGKPNCLVIDEIDGAPVA-AINVLLSILNRKGPQEVGPQGPAVPSGGGRRRRAEGGLLMRPIICICNDQFAPSLRQLKQQAFLLHFPPTLPSRLVQRLQEVSLRQGMRADPGVLAALCEKTDNDIRACINTLQFLYSRGQRELSVRDVQATRVGLKDQRRGLFSVWQEVFQLPRAQRRRVGQDPALPADTLLLGDGDAGSLTSASQRFYRVLHAAASAGEHEKVVQGLFDNFLRLRLRDSSLGAVCVALDWLAFDDLLAGAAHHSQSFQLLRYPPFLPVAFHVLFASSHTP-RITFPSS---QQEAQNRMSQMRNLIQTLVSGIAPATRSRATPQALLLDALCLLLDILAPKLRPVSTQLYSTREKQQLASLVGTMLAYSLTYRQERTPDGQYIYRLEPNVEELCRFPELPARKPLTYQTKQLIAREIEVEKMRRAEASARVENSPQVDGSPPGLEGLLGGIGEKGVHRPAPRNHEQRLEHIMRRAAREEQPEKDFFGRV---------------------VVRSTAVPSAG---------DTAP-------------------------------------EQDSVERRMGTAVGRSEVWFRFNEGVSN-----------------------------AVR-------------RSLYIRDLL-------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IQ05-1", "uniprot_id": "CTF18_DROME", "id": "Q8IQ05-1", "name": "Chromosome transmission fidelity protein 18 homolog", "aln": "MDQYPDENEEFELQYQDELELLEDLPDEFNAYDGPSTSKQAAEKQKENRAPVAALRDSTRLGNSTLGSPQLSQITFGASQLGGEEEAEGTSSGGQVNRRLFGTPKGPPVGRGCSTPFQRMPAIQELENTQLTSRSYGLEKENAAANQLQEVGLKNVNKRRLERDLFGDIDDLFHESYEDPMVKKARTEEQRDHEAIERILELRRKMRESSKTLRKDDVSRLKALHDFKMRNLSYEIPNWPFLAIQRSDLERIYVRFHSEDYEQRQLDLISARGEVVGSLLGEAKDKIWQEAGEIVLSRATAAEDADVTLVNSNANSEPGRLWVDKYKPRKYIDLLSDEMTNRSLLYWLKMWDKVVFGKAFHSKREQEAVTGEGGTAGGAANQLNSFNKRTGKFESNGGWRQRKSRQALNTNVDALGRPMQKVALLCGPPGLGKTTLAHTIARHAGYNVREINASDDRSPEAFKLALENGTQMSSVLNEDKRPNCIVLDEIDGAPRQ-SIDYLVKFISDAVYTKVKAKG----------AKAEHNVLKRPIICICNDVYDPALRPLRQVAFVVTFPPIDAARLAERLVKIAFKEQLKTDFGSLIALAEKSGNDVRSCISSMQFFN-AQKHSLTLQDVLNNNLGQKDRHQGLFAVWDAIFRIQRPRKTLHTDANKVDEPAQVTMTN-----TSVTTRVRNVLEVVHSSGDYERLTQGVYENYLQQKMPDPNFTGVCEALKWFCFTDTVQHQISRQQNYSVYPYLQYGFVAWHLLFATLAWP-KIAFPTR---GFEFQQKSTNQRNIFQALCKGVTTSALGVGQGGTLLLDTVPLLKRILSPQLRSVAVQLLSPKEQQDLRHTIEVMVDLGLTFVQVKSQEGHYVFQTEPDLDALSAFPGYTG-LSLPYFSRQLIAREVDLERIRRAAPKGGAPSAPAAKKKTSGAAAQLPN--HLQTLKPKPISASN------MHSAPKQQLTKDFFGRIT---------------------------------------HKSTS--------------------------------------TNSAEESKTDAIVKSPIWYRYKEGFNN-----------------------------AVR-------------KDVHIHELL-------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P49956-1", "uniprot_id": "CTF18_YEAST", "id": "P49956-1", "name": "Chromosome transmission fidelity protein 18", "aln": "-----------------------------------------------------------------------------------------------------MVDTAPYIGS-------------------------------LGRSSLFDTGDIEQAPGNNAIGINEEDIHAFVSSTGETVQLKKKP-----------AKLATGNISLYTN-------------------------PDTVWRSD---DTYGININYLLDKIEASGDD--RTNAQKTSPITGKIGS---------------------------------DTLWVEKWRPKKFLDLVGNEKTNRRMLGWLRQWTPAVFKEQLP--------------------------------------KLPTEKEVSDMELDPLKRPPKKILLLHGPPGIGKTSVAHVIAKQSGFSVSEINASDERAGPMVKEKIYNLLFNHTFDTN---PVCLVADEIDGSIESGFIRILVDIMQSDIKATNKLLYGQPDKKDKKRKKKRSKLLTRPIICICNNLYAPSLEKLKPFCEIIAVKRPSDTTLLERLNLICHKENMNIPIKAINDLIDLAQGDVRNCINNLQFLA---------SNVDSRDSSASDKPACAKNTWASSNKDSPISWFKIVNQLFRKDPHR-----------DIKEQFYELLNQVELNGNSDRILQGCFNIFPYVKYSDNGIRKPANISDWLFFHDLMYQSMYAHN-GELLRYSALVPLVFFQTFGDIANKDDIRMKNSEYEQRELKRANSDIVSLIMRHISVQSPLMASFTDRKSLIFEILPYLDSMISSDFNKIRNLKLKQAIMEELVQLLKSFQLN-LIQNRSEGFDVRGGLTIDPPIDEVVLLNPKHINEVQHKRANNLSSLLAKIEENRAKKRHIDQVTEDRLQSQEMHSKKVKTGLNSSSSTIDFFKNQYGLLKQTQELEETQKTIGSD-------------------------------------------------------------------------------------------ETNQADDCNQTVKIWVKYNEGFSN-------------------------AVR-----------------KNVTWNNLWE------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* : : : : .: : : . : :. . : . * : . .. : : .: . . . ***::: *::: :*:.:: *** :* **: * .** . : .: : :*. ** :*: ** ****:***::**.:*:::*: * *:****:*: .: : :. * *:* *****: * *: ::. : . :* ********: : *:*. *: . :: . : * :** :. :. :. : * : : .*:* **..:**: * . .*: .* : : . :. .:*. . *: ::: ** :: : : * .: . .*: * * : : .: * .:. *. * : . * : :: . : . :. . :*::: : * :::..:. : . ::* : : * : . : : :* :: : : :.:* : .:*. . . . :: . * *. :.: .. ", "identical_positions": 96, "similar_positions": 193, "identity": "7.98%" }, { "cls_id": "homologset.agr.SGD:S000004684", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZQG0-1", "uniprot_id": "A0A8I5ZQG0_RAT", "id": "A0A8I5ZQG0-1", "name": "SEC14-like protein 1", "aln": "MVQKYQSPVRVYKHPFELIMAAYERRFPTCPLIPMFVDSDTVSEFKSEDGAIHVIERRCKLDIDAPRLLKKIAGVDYVYFVQKNSLNSRDRTLHIEAHNETFSNRVIIHEHCCYTVHPENEDWTCFEQSASLDIKSFFGFESTVEKIAMKHYTSNIKKGKEIIEYYLRQLEEEGITFVPRWTPPPTGPSSETCSSS-KNQAASAAVLVPDAAAVKEGLSGEVLSSPGTVAEPVVGTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWLQETHKGK-IPKDEHILRFLRARDFNIDKAREIMCQSLTWRKQHQVDYILDTWTPPQ--VLQDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGLR-RCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRRKFLIYAGNDYQGPGGLLDYIDKEIIPDFLSGECMCDVPEGGLVPKSLYRTPEELE-NEDLKLWTETIYQSASVFKGAPHEILIQIVDAASVITWDFDVCKGDIVFNIYHSKRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGRDYSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHTMPACAATNLPRVDDVLASLQVSSHKCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSS--QSHSSSMISSE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8Y5H7-1", "uniprot_id": "S14L1_MOUSE", "id": "A8Y5H7-1", "name": "SEC14-like protein 1", "aln": "MVQKYQSPVRVYKHPFELIMAAYERRFPTCPLIPMFVDSDTVSEFKSEDGALHVIERRCKLDIDAPRLLKKIAGVDYVYFVQKNSLNSRDRTLHIEAHNETFSNRVIIHEHCCYTVHPENEDWTCFEQSASLDIKSFFGFESTVEKIAMKHYTSNIKKGKEIIEYYLRQLEEEGITFVPRWTPPPVGPS-ETCSSS-KNQVTSAAVLVPDAAAVMEGLSGENLSSPGTASEPVVGTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWLQETHKGK-IPKDEHILRFLRARDFNIDKAREIMCQSLTWRKQHQVDYILDTWTPPQ--VLLDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGLR-RCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRRKFLIYAGNDYQGPGGLLDYIDKEIIPDFLSGECMCDVPEGGLVPKSLYRTAEELE-NEDLKLWTETIYQSASVFKGAPHEILIQIVDASSVITWDFDVCKGDIVFNIYHSKRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGRDYSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHTMPACAATNLPRVDDVLASLQVSSHKCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSS--QSQSSSMISR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92503-1", "uniprot_id": "S14L1_HUMAN", "id": "Q92503-1", "name": "SEC14-like protein 1", "aln": "MVQKYQSPVRVYKYPFELIMAAYERRFPTCPLIPMFVGSDTVNEFKSEDGAIHVIERRCKLDVDAPRLLKKIAGVDYVYFVQKNSLNSRERTLHIEAYNETFSNRVIINEHCCYTVHPENEDWTCFEQSASLDIKSFFGFESTVEKIAMKQYTSNIKKGKEIIEYYLRQLEEEGITFVPRWSPPSITTSSETSSSSSKKQAASMAVVIP-EAALKEGLSGDALSSP-SAPEPVVGTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWLQETHKGK-IPKDEHILRFLRARDFNIDKAREIMCQSLTWRKQHQVDYILETWTPPQ--VLQDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGLR-RCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRRKFLIYAGNDYQGPGGLLDYIDKEIIPDFLSGECMCEVPEGGLVPKSLYRTAEELE-NEDLKLWTETIYQSASVFKGAPHEILIQIVDASSVITWDFDVCKGDIVFNIYHSKRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGRDYSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHSMPACAASSLPRVDDVLASLQVSSHKCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSS--QSHSSSMISR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O43304-1", "uniprot_id": "S14L5_HUMAN", "id": "O43304-1", "name": "SEC14-like protein 5", "aln": "MVQRYQSPVRVYKYPFELVMAAYEKRFPTCPQIPVFLGSEVLRESRSPDGAVHVVERSCRLRVDAPRLLRKIAGVEHVVFVQTNILNWKERTLLIEAHNETFANRVVVNEHCSYTVHPENEDWTCFEQSASLDIRSFFGFENALEKIAMKQYTANVKRGKEVIEHYLNELISQGTSHIPRWTPAPVREEDARNQAG---------------PRDPSSLEAHGPRSTLGPALEAVSMDGDKLDADYIERCLGHLTPMQESCLIQLRHWLQETHKGK-IPKDEHILRFLRAHDFHLDKAREMLRQSLSWRKQHQVDLLLQTWQPPA--LLEEFYAGGWHYQDIDGRPLYILRLGQMDTKGLMKAVGEEALLRHVLSVNEEGQK-RCEGSTRQLGRPISSWTCLLDLEGLNMRHLWRPGVKALLRMIEVVEDNYPETLGRLLIVRAPRVFPVLWTLISPFINENTRRKFLIYSGSNYQGPGGLVDYLDREVIPDFLGGESVCNVPEGGLVPKSLYMTEEEQEHTDQLWQWSET-YHSASVLRGAPHEVAVEILEGESVITWDFDILRGDVVFSLYHTKQAPRLGARE----PGTRASG----QLIDKGWVLGRDYSRVEAPLVCREGESIQGSHVTRWPGVYLLQWQMHSPPSSVACSLPGVDDVLTALHSPGPKCKLLYYCEVLASEDFRGSMSSLESCTSGFSQLSAATSSSSSGQSHSSSLVSR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A8B0-1", "uniprot_id": "D4A8B0_RAT", "id": "D4A8B0-1", "name": "", "aln": "MVQKYQSPVRVYKYPFELVMAAYEKRFPTCPLIPVFLGSEVLSECRSADGAVHTVERSCRLRVDAPRLLRKIAGVEHVVFIQRNVLNWRERTLLIDAHNETFASRVTVKEHCRYTVHPENEDWTCFEQSASLDVRSFFGFESTLEKIAMKQYTANVKRGKEVIEHYLSELISQGASHIPRWTPAPVREADVRSQLV---------------CPCPSSLETDGPSDAPAPASEMATADGDKLDADYIERCLGHLSPMQESCLVQLRRWLQETHKGK-IPKDEHILRFLRARDFHLDKARDMLCQSLSWRKQHQVDLLLQTWRPPA--PLQEFYAGGWHYQDIDGRPLYILRLGQMDTKGLMKAVGEEALLQHVLSVNEEGQK-RCEGNTRQFGRPISSWTCLLDLEGLNMRHLWRPGVKALLRMIEVVEDNYPETLGRLLIVRAPRVFPVLWTLVSPFINENTRRKFLIYSGSNYQGPGGLVDYLDKDVIPDFLGGESVCNVPEGGMVPKSLYLTEEEQEQADQLRQWSET-YHSASVLRGSPHEVAMEIPEGESVITWDFDILRGDVVFSLYHAKQAPKLSPQE----PGVRASG----QLIDKNWILGVDYSRVEAPLICREGQSIQGSHVTQWPGVYLLQWQIHSPPESVACSLPGVDDVLTALHSPGPKCKLLYYCEVLASEDFRGSMSSLESCASRFSQLSATTTSSSSGQSHSGSMVSR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0F9-1", "uniprot_id": "S14L4_MOUSE", "id": "Q8R0F9-1", "name": "SEC14-like protein 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRGQVGDLSPQQQEALARFRETLQDLLPTLPKADDYFLLRWLRARNFDLKKSEDMLRKHVEFRNQQNLDQILT-WQAPE--VIQLYDSGGLSGYDYEGCPVWFDIIGTMDPKGLFMSASKQDMIRKRIKVCEMLLH-ECELQSQKLGRKIERMVMVFDMEGLSLRHLWKPAVEVYQQFFAILEANYPETVKNLIIIRAPKLFPVAFNLVKSFMGEETQKKIVILG-GNWKQE--LVKFVSPDQLPVEFGG-TMTDPDGNPKCLTKINYGGEVPKRYYLSNQERPQYEHSVVVGRGSSHQVENEILFPGCVLRWQFASDGGDIGFGVFLKTR-------------------------MGERQKAGEMVEVLPSQRYNAHMVPEDGSLNCLKAGVYVLRFDNT--------------------YSLLHTKKVGYTAEVLLPD---------KACEEKLQGLGSVSPP---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UDX3-1", "uniprot_id": "S14L4_HUMAN", "id": "Q9UDX3-1", "name": "SEC14-like protein 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSRVGDLSPQQQEALARFRENLQDLLPILPNADDYFLLRWLRARNFDLQKSEDMLRRHMEFRKQQDLDNIVT-WQPPE--VIQLYDSGGLCGYDYEGCPVYFNIIGSLDPKGLLLSASKQDMIRKRIKVCELLLH-ECELQTQKLGRKIEMALMVFDMEGLSLKHLWKPAVEVYQQFFSILEANYPETLKNLIVIRAPKLFPVAFNLVKSFMSEETRRKIVILG-DNWKQE--LTKFISPDQLPVEFGG-TMTDPDGNPKCLTKINYGGEVPKSYYLCEQVRLQYEHTRSVGRGSSLQVENEILFPGCVLRWQFASDGGDIGFGVFLKTK-------------------------MGEQQSAREMTEVLPSQRYNAHMVPEDGSLTCLQAGVYVLRFDNT--------------------YSRMHAKKLSYTVEVLLPD---------KASEETLQSLKAMRPSPTQ------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B5MCN3-1", "uniprot_id": "S14L6_HUMAN", "id": "B5MCN3-1", "name": "SEC14-like protein 6", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGQVGDLSPSQEKSLAQFRENIQDVLSALPNPDDYFLLRWLQARSFDLQKSEDMLRKHMEFRKQQDLANILA-WQPPE--VVRLYNANGICGHDGEGSPVWYHIVGSLDPKGLLLSASKQELLRDSFRSCELLLR-ECELQSQKLGKRVEKIIAIFGLEGLGLRDLWKPGIELLQEFFSALEANYPEILKSLIVVRAPKLFAVAFNLVKSYMSEETRRKVVILG-DNWKQE--LTKFISPDQLPVEFGG-TMTDPDGNPKCLTKINYGGEVPKSYYLCKQVRLQYEHTRSVGRGSSLQVENEILFPGCVLRWQFASDGGDIGFGVFLKTK-------------------------MGERQRAREMTEVLPSQRYNAHMVPEDGILTCLQAGSYVLRFYNT--------------------YSLVHSKRISYTVEVLLPD---------QTFMEKMEKF---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SQ27-1", "uniprot_id": "Q5SQ27_MOUSE", "id": "Q5SQ27-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGRVGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRARNFDLQKSEAMLRKYMEFRKTMDIDHILD-WQPPE--VIQKYMPGGLCGYDRDGCPVWYDIIGPLDPKGLLFSVTKQDLLKTKMRDCERILH-ECDLQTERLGRKIETIVMIFDCEGLGLKHFWKPLVEVYQEFFGLLEENYPETLKFMLIVKATKLFPVGYNLMKPFLSEDTRRKIVVLGSNSWKEG--LLKLISPEELPAHFGG-TLTDPDGNPKCLTKINYGGEIPKSMYVRDQVKTQYEHSVQISRGSSHQVEYEILFPGCVLRWQFSSDGADIGFGVFLKTK-------------------------MGERQKAGEMVEVLTSQRYNAHMVPEDGSLTCSEAGVYVLRFDNT--------------------YSFVHAKKVSFTVEVLLPD---------EGMQKYDEELTPV------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z1J8-1", "uniprot_id": "S14L3_RAT", "id": "Q9Z1J8-1", "name": "SEC14-like protein 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGRVGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRARNFDLQKSEAMLRKYMEFRKTMDIDHILD-WQPPE--VIQKYMPGGLCGYDRDGCPVWYDIIGPLDPKGLLFSVTKQDLLKTKMRDCERILH-ECDLQTERLGRKIETIVMIFDCEGLGLKHFWKPLVEVYQEFFGLLEENYPETLKFMLIVKATKLFPVGYNLMKPFLSEDTRRKIVVLG-NSWKEG--LLKLISPEELPAHFGG-TLTDPDGNPKCLTKINYGGEIPKSMYVRDQVKTQYEHSVQISRGSSHQVEYEILFPGCVLRWQFSSDGADIGFGVFLKTK-------------------------MGERQKAGEMTEVLTSQRYNAHMVPEDGSLTCTEAGVYVLRFDNT--------------------YSFVHAKKVSFTVEVLLPD---------EGMQKYDEELTPI------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UDX4-1", "uniprot_id": "S14L3_HUMAN", "id": "Q9UDX4-1", "name": "SEC14-like protein 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGRVGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRARNFDLQKSEALLRKYMEFRKTMDIDHILD-WQPPE--VIQKYMPGGLCGYDRDGCPVWYDIIGPLDPKGLLFSVTKQDLLKTKMRDCERILH-ECDLQTERLGKKIETIVMIFDCEGLGLKHFWKPLVEVYQEFFGLLEENYPETLKFMLIVKATKLFPVGYNLMKPFLSEDTRRKIIVLG-NNWKEG--LLKLISPEELPAQFGG-TLTDPDGNPKCLTKINYGGEIPKSMYVRDQVKTQYEHSVQINRGSSHQVEYEILFPGCVLRWQFSSDGADIGFGVFLKTK-------------------------MGERQRAGEMTDVLPSQRYNAHMVPEDGNLTCSEAGVYVLRFDNT--------------------YSFVHAKKVSFTVEVLLPD---------EGMQKYDKELTPV------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99J08-1", "uniprot_id": "S14L2_MOUSE", "id": "Q99J08-1", "name": "SEC14-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGRVGDLSPKQEEALAKFRENVQDVLPTLPNPDDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQKDIDKIIS-WQPPE--VIQQYLSGGRCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDLLRTKMRDCELLLQ-ECIQQTTKLGKKIETITMIYDCEGLGLKHLWKPAVEAYGEFLTMFEENYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRRKIMVLG-ANWKEV--LLKHISPDQLPVEYGG-TMTDPDGNPKCKSKINYGGDIPKQYYVRDQVKQQYEHTVQVSRGSSHQVEYEILFPGCVLRWQFMSEGSDVGFGIFLKTK-------------------------MGERQRAGEMTEVLPNQRYNSHMVPEDGTLTCSEPGIYVLRFDNT--------------------YSFIHAKKVSFTVEVLLPD---------KAAEEKMNQQGADTPK---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99MS0-1", "uniprot_id": "S14L2_RAT", "id": "Q99MS0-1", "name": "SEC14-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGRVGDLSPKQEEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQKDIDKIIS-WQPPE--VIQQYLSGGRCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDLLRTKMRDCELLLQ-ECTQQTAKLGKKIETITMIYDCEGLGLKHLWKPAVEAYGEFLTMFEENYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLG-ANWKEV--LLKHISPDQLPVEYGG-TMTDPDGNPKCKSKINYGGDIPKQYYVRDQVKQQYEHSVQISRGSSHQVEYEILFPGCVLRWQFMSEGSDVGFGIFLKTK-------------------------MGERQRAGEMTEVLPNQRYNSHMVPEDGTLTCSEPGIYVLRFDNT--------------------YSFIHAKKVSFTVEVLLPD---------KAAEEKLNQQGAVTPK---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O76054-1", "uniprot_id": "S14L2_HUMAN", "id": "O76054-1", "name": "SEC14-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQKDIDNIIS-WQPPE--VIQQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDLLRTKMRECELLLQ-ECAHQTTKLGRKVETITIIYDCEGLGLKHLWKPAVEAYGEFLCMFEENYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLG-ANWKEV--LLKHISPDQVPVEYGG-TMTDPDGNPKCKSKINYGGDIPRKYYVRDQVKQQYEHSVQISRGSSHQVEYEILFPGCVLRWQFMSDGADVGFGIFLKTK-------------------------MGERQRAGEMTEVLPNQRYNSHLVPEDGTLTCSDPGIYVLRFDNT--------------------YSFIHAKKVNFTVEVLLPD---------KASEEKMKQLGAGTPK---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P24280-1", "uniprot_id": "SEC14_YEAST", "id": "P24280-1", "name": "SEC14 cytosolic factor", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVTQQEKEFLESYPQNCPPDALPGTPGNLDSAQEKALAELRKLLED-AGFIERLDDSTLLRFLRARKFDVQLAKEMFENCEKWRKDYGTDTILQDFHYDEKPLIAKFYPQYYHKTDKDGRPVYFEELGAVNLHEMNKVTSEERMLKNLVWEYESVVQYRLPACSRAAGHLVETSCTIMDLKGISISSAYS-VMSYVREASYISQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFILG-SSYQKE--LLKQIPAENLPVKFGGKSEVDESKGGLYLSDIG-----------------PWRDPKYIGPEGEAPEAFSMK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.* . * . * .:*. ::: .* :**:*:*:.*.:. :. :: . :*: :: : : : . * :* *:: :* :: : : :: ::: . * : . : *: :. : . :*:.: : :. . : *** : : ::.*. *.. : *...::. * *..: . .:: * . : : :* .* : . ..: .. : . .: ", "identical_positions": 30, "similar_positions": 101, "identity": "4.14%" }, { "cls_id": "homologset.agr.SGD:S000004685", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0U1RS25-1", "uniprot_id": "A0A0U1RS25_RAT", "id": "A0A0U1RS25-1", "name": "Regulator of nonsense transcripts 1", "aln": "MSVEAYGPSSQTLTFLDTEEAELL-GADTQGSEFEFTDFTLPSQTQTPPGGPGG-----AGGPGGAGAGGAAGQLDAQV-GPEGILQNGAVDDSVAKTSQLLAELNFEEDEED--TYYTKDLPVHACSYCGIHDPACVVYCNTSKKWFCNGRGNTSGSHIVNHLVRAKCKEVTLHKDGPLGETVLECYNCGCRNVFLLGFIPAKADSVVVLLCRQPCASQSSLKDINWDSSQWQPLIQDRCFLSWLVKIPSEQEQLRARQITAQQINKLEELWKENPSATLEDLEKPGVDEEPQHVLLRYEDAYQYQNIFGPLVKLEADYDKKLKESQTQDNITVRWDLGLNKKRIAFFTLPKTDSGNEDLVIIWLRDMRLMQGDEICLRYKGDLAPLWKGIGHVIKVPDNYGDEIAIELRSS-VGAPVEVTHNFQVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGH----EVEDVVIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELSSADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLSYYKEQKALVEGPLNNLRESLMQFSKPRKLVNTVNPGARFMTTAMYDAREAIIPGSVYDRSS---QGR-----------------------------PSN------------------------------MYFQTHDQISMIS--AGPSHVAAMNIPIPFNLVMPPMPP----------------------PGYFGQANGPAAGRGTPKSKTG-RGGRQKNR-FGLP---GPSQTTLPNSQASQDVASQPFSQGALTQGYVSMSQPSQMSQPGLSQPELSQDSYLGDEFKSQIDVALSQDSTYQGERAYQHGGVTGLSQY--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPU0-1", "uniprot_id": "RENT1_MOUSE", "id": "Q9EPU0-1", "name": "Regulator of nonsense transcripts 1", "aln": "MSVEAYGPSSQTLTFLDTEEAELL-GADTQGSEFEFTDFTLPSQTQTPPGGPGG-----AGGPGGAGAGGAAGQLDAQV-GPEGILQNGAVDDSVAKTSQLLAELNFEEDEED--TYYTKDLPVHACSYCGIHDPACVVYCNTSKKWFCNGRGNTSGSHIVNHLVRAKCKEVTLHKDGPLGETVLECYNCGCRNVFLLGFIPAKADSVVVLLCRQPCASQSSLKDINWDSSQWQPLIQDRCFLSWLVKIPSEQEQLRARQITAQQINKLEELWKENPSATLEDLEKPGVDEEPQHVLLRYEDAYQYQNIFGPLVKLEADYDKKLKESQTQDNITVRWDLGLNKKRIAFFTLPKTDSGNEDLVIIWLRDMRLMQGDEICLRYKGDLAPLWKGIGHVIKVPDNYGDEIAIELRSS-VGAPVEVTHNFQVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGH----EVEDVVIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELSSADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLSYYKEQKALVEGPLNNLRESLMQFSKPRKLVNTVNPGARFMTTAMYDAREAIIPGSVYDRSS---QGR-----------------------------PSN------------------------------MYFQTHDQISMIS--AGPSHVAAMNIPIPFNLVMPPMPP----------------------PGYFGQANGPAAGRGTPKTKTG-RGGRQKNR-FGLP---GPSQTTLPNSQASQDVASQPFSQGALTQGYVSMSQPSQMSQPGLSQPELSQDSYLGDEFKSQIDVALSQDSTYQGERAYQHGGVTGLSQY--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92900-1", "uniprot_id": "RENT1_HUMAN", "id": "Q92900-1", "name": "Regulator of nonsense transcripts 1", "aln": "MSVEAYGPSSQTLTFLDTEEAELL-GADTQGSEFEFTDFTLPSQTQTPPGGPGGPGGGGAGGPGGAGAGAAAGQLDAQV-GPEGILQNGAVDDSVAKTSQLLAELNFEEDEED--TYYTKDLPIHACSYCGIHDPACVVYCNTSKKWFCNGRGNTSGSHIVNHLVRAKCKEVTLHKDGPLGETVLECYNCGCRNVFLLGFIPAKADSVVVLLCRQPCASQSSLKDINWDSSQWQPLIQDRCFLSWLVKIPSEQEQLRARQITAQQINKLEELWKENPSATLEDLEKPGVDEEPQHVLLRYEDAYQYQNIFGPLVKLEADYDKKLKESQTQDNITVRWDLGLNKKRIAYFTLPKTDSGNEDLVIIWLRDMRLMQGDEICLRYKGDLAPLWKGIGHVIKVPDNYGDEIAIELRSS-VGAPVEVTHNFQVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGH----EVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELSSADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGPLNNLRESLMQFSKPRKLVNTINPGARFMTTAMYDAREAIIPGSVYDRSS---QGR-----------------------------PSS------------------------------MYFQTHDQIGMIS--AGPSHVAAMNIPIPFNLVMPPMPP----------------------PGYFGQANGPAAGRGTPKGKTG-RGGRQKNR-FGLP---GPSQTNLPNSQASQDVASQPFSQGALTQGYISMSQPSQMSQPGLSQPELSQDSYLGDEFKSQIDVALSQDSTYQGERAYQHGGVTGLSQY--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RCY6-1", "uniprot_id": "RENT1_DANRE", "id": "F1RCY6-1", "name": "Regulator of nonsense transcripts 1", "aln": "MSVEAYGPSSQTLTFLDTEEAELL-GADTQGSEFEFTDFTLPSQTQT--------------------QGQTQSQLDNQVNGPDGVLPNG--EDAVGKTSQLLAELNFEEDEED--TYYTKDLPVHACSYCGIHDPACVVYCNTSKKWFCNGRGNTSGSHIVNHLVRAKCKEVTLHKDGPLGETVLECYNCGCRNVFLLGFIPAKADSVVVLLCRQPCASQSSLKDINWDSSQWQPLIQDRCFLSWLVKIPSEQEQLRARQITAQQINKLEELWKENPTATLEDLEKPGVDEEPQHVLLRYEDAYQYQNIFGPLVKLEADYDKKLKESQTQDNITVRWDLGLNKKRIAYFTLPKTDSG----------DMRLMQGDEICLRYKGDMAPLWKGIGHVIKVPDNYGDEIAIELRSS-AGAPVEVPHNFQVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGH----EVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELSSSDEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRLKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTEAANVEKITTRLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGPLNNLRESLMQFSKPRKLVNTINPGARFMSTAMYDAREAMIPGSVYDRSS---TGR-----------------------------PSN------------------------------MYFQTHDQVGMIG--TGPNPMGSLNIPIPFNLVMPPMPP----------------------PGYLGQVNGPAAGRGAPKGKTGGRGGRQRNRGTGNH---GSGQPNMPNSQASQDLVSQPFSQGPLTQGYITMSQPSQMSQPGLSQPELSQDSYLGDEFKSQMDVALSQDSTYQGERAYQHGGVTGLSQY--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYS3-1", "uniprot_id": "RENT1_DROME", "id": "Q9VYS3-1", "name": "Regulator of nonsense transcripts 1 homolog", "aln": "MSVDTYAPSS-ALSFLDMDDNELLPGADTQPTQYDYRDFTMPSTSQS---------------------QTQNDQLEIAQ-----RCSAGDSHPRLASITNDLADLQFEEEDDEPGSSYVKELPPHACKYCGIHDPATVVMCNNCRKWFCNGRGSTSGSHIINHLVRAKHREVTLHGEGPLGETILECYSCGVRNVFVLGFIPAKADSVVVLLCRQPCAAQNSLKDMNWDQEQWKPLIADRCFLAWLVKQPSEQGQLRARQISAAQINKLEELWKENIEATFQDLEKPGIDSEPAHVLLRYEDGYQYEKTFGPLVRLEAEYDQKLKESATQENIEVRWDVGLNKKTIAYFTLAKTDSD-----------MKLMHGDELRLHYVGELYNPWSEIGHVIKVPDNFGDDVGLELKSS-TNAPVKCTSNFTVDFIWKCTSFDRMTRALCKFAIDRNSVSNFIYSRLLGHGRADSNDEVLFRGPQPKLFSAPHLPDLNRSQVYAVKHALQRPLSLIQGPPGTGKTVTSATIVYQLVKLHGGTVLVCAPSNTAVDQLTEKIHRTNLKVVRVCAKSREAIDSPVSFLALHNQIRNMETNSELKKLQQLKDETGELSSADEKRYRNLKRAAENQLLEAADVICCTCVGAGDGRLSRVKFTSILIDESMQSTEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAARAGLSQSLFERLVVLGIRPFRLEVQYRMHPELSQFPSNFFYEGSLQNGVCAEDRRLK-LDFPWPQPERPMFFLVTQGQEEIAGSGTSFLNRTEAANVEKITTRFLKAGIKPEQIGIITPYEGQRAYLVQYMQYQGSLHSRLYQEIEIASVDAFQGREKDIIIMSCVRSNERQGIGFLNDPRRLNVALTRAKFGIIIVGNPKVLAKQQLWNHLLNFYKDRKVLVEGSLNNLKESLIHFQKPKKLVNSMNIGAHFMSTIIADAKEVMVPGSIYDRSGGYGQGRQMVGQSMNGGQYGGSGGGPYGNSPLGYGTPSSNSMVGFGLGNGGNGAAGGNNNFGGAGPSWAAAHLHHDSIGYISNEHGAAALGNMPVPVGMFMNMSNIPPRFYNQHQQAIMAVKQNRAIQQQTGNFSPGNSGPGVTGVGVGRSATPGGNKKTNKLGKSRVTGGGTGGAPLTQGSSVCNAAPYSQHPMPLS-LQMTQPSGFALS--QQPELSQD--FG--QISQMDGLLSQDVAFN---ASGERSLNQFSQPY-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P30771-1", "uniprot_id": "RENT1_YEAST", "id": "P30771-1", "name": "ATP-dependent helicase NAM7", "aln": "-----------------------MVGSGSH-TPYDISNSPSDVNVQP------------------------ATQLNSTL-----------------VEDDDVDNQLFEEAQVTETGFRSPSASDNSCAYCGIDSAKCVIKCNSCKKWFCNTKNGTSSSHIVNHLVLSHHNVVSLHPDSDLGDTVLECYNCGRKNVFLLGFVSAKSEAVVVLLCRIPCAQT---KNANWDTDQWQPLIEDRQLLSWVAEQPTEEEKLKARLITPSQISKLEAKWRSNKDATINDIDAPEEQEAIPPLLLRYQDAYEYQRSYGPLIKLEADYDKQLKESQALEHISVSWSLALNNRHLASFTLSTFESN----------ELKVAIGDEMILWYSGMQHPDWEGRGYIVRLPNSFQDTFTLELKPSKTPPPTHLTTGFTAEFIWKGTSYDRMQDALKKFAIDKKSISGYLYYKILGH----QVVDISFDVPLPKEFSIPNFAQLNSSQSNAVSHVLQRPLSLIQGPPGTGKTVTSATIVYHLSKIHKDRILVCAPSNVAVDHLAAKLRDLGLKVVRLTAKSREDVESSVSNLALHNLVG-RGAKGELKNLLKLKDEVGELSASDTKRFVKLVRKTEAEILNKADVVCCTCVGAGDKRLD-TKFRTVLIDESTQASEPECLIPIVKGAKQVILVGDHQQLGPVILERKAADAGLKQSLFERLISLGHVPIRLEVQYRMNPYLSEFPSNMFYEGSLQNGVTIEQRTVPNSKFPWPIRGIPMMFWANYGREEISANGTSFLNRIEAMNCERIITKLFRDGVKPEQIGVITPYEGQRAYILQYMQMNGSLDKDLYIKVEVASVDAFQGREKDYIILSCVRANEQQAIGFLRDPRRLNVGLTRAKYGLVILGNPRSLARNTLWNHLLIHFREKGCLVEGTLDNLQLCTVQLVRPQPRKTERPMNAQFN-----------VESEMGDFPK----------------------------------------------------------------------FQDFDAQSMVS---------------------------------------------------FS-------------GQIG-----------------DFGNAFVDNTELSSYINNEYWNFENFKSAFSQKQNRNEIDDRNLYQEEASHLN-------SNFARELQRE-------EQKHELSKDFSNLGI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:.:: : :: : . *. **: : : : *** : . . ::* ****... *: **..:***** :..**.***:**** :: . *:** :. **:*:****.** :***:***:.**:::******* *** *: *** .**:*** ** :*:*:.: *:*: :*:** *:. **.*** *:.* **::*:: * :. :****:*.*:*:. :***::***:**::**** : ::* * *.:.**:: :* ***.. :*. ::: ***: * * * *. *:::::*:.: * . :**:.* . .*.. . .* .:*:** **:*** ** .**:*..*:*.::* ::*** . :: : ** *: :.:** ** **. .*************************:* : . :******* ***:*: *:: .*****: ***** ::*.** ***** : : **::* :****.****::* **: * * :* ::* ***:********* ** :* ::***** *::****::*:* ****:****** *****:: :*** ***.*******: ** *:**:*****:* ** ****:********** :* .* ** **:* .. *:***:..***:*** ** * *:* *:::: * **:***:********:*::**** .***.. ** ::*:************ **:****:**:*.****.*******.****::*::*:***: *::: ****** .:::: ****.*:**: . ::: :*: . .*:* : ..: * . . .* . :. :. : . . . :: *. :. : . : . : * * *: *:: *.:: . . :*: ", "identical_positions": 432, "similar_positions": 281, "identity": "35.09%" }, { "cls_id": "homologset.agr.SGD:S000004689", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P47856-1", "uniprot_id": "GFPT1_MOUSE", "id": "P47856-1", "name": "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "aln": "MCGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGLDGGNDKDWEANACKIQLIKKKGKVKALDEEVHKQQDMDLDIEFDVHLGIAHTRWATHGEPNPVNSHPQRSDKNNEFIVIHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDNWESQ--DVSFTTLVERVIQQLEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILYRTARTQIGSTW--WGSQAERGKDKKGSCGLSRVDSTTCLFPVEEKAVEYYFASDASAVIEHTNRVIFLEDDDVAAVVDGRLSIHRIKRTAGDHPGRAVQTLQMELQQIMKGNFSSFMQKEIFEQPESVVNTMRGRVNFDDYTVNLGGLKDHIKEIQRCRRLILIACGTSYHAGVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLMGLRYCKERGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFALMMCDDRISMQERRKEIMLGLKRLPDLIKEVLSMDDEIQKLATELYHQKSVLIMGRGYHYATCLEGALKIKEITYMHSEGILAGELKHGPLALVDKLMPVIMIIMRDHTYAKCQNALQQVVARQGRPVVICDKEDTETIKNTKRTIKVPHSVDCLQGILSVIPLQLLAFHLAVLRGYDVDFPRNLAKSVTVE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P82808-1", "uniprot_id": "GFPT1_RAT", "id": "P82808-1", "name": "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "aln": "MCGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGLDGGNDKDWEANACKIQLIKKKGKVKALDEEVHKQQDMDLDIEFDVHLGIAHTRWATHGEPSPVNSHPQRSDKNNEFIVIHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDNWESQ--DVSFTTLVERVIQQLEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILYRTG------------------KDKKGSCGLSRVDSTTCLFPVEEKAVEYYFASDASAVIEHTNRVIFLEDDDVAAVVDGRLSIHRIKRTARDHPGRAVQTLQMELQQIMKGNFSSFMQKEIFEQPESVVNTMRGRVNFDDYTVNLGGLKDHIKEIQRCRRLILIACGTSYHAGMATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLMGLRYCKERGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFALMMCDDRISMQERRKEIMLGLKRLPDLIKEVLSMDDEIQKLATELYHQKSVLIMGRGYHYATCLEGALKIKEITYMHSEGILAGELKHGPLALVDKLMPVIMIIMRDHTYAKCQNALQQVVARQGRPVVICDKEDTETIKNTKRTIKVPHSVDCLQGILSVIPLQLLAFHLAVLRGYDVDFPRNLAKSVTVE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q06210-1", "uniprot_id": "GFPT1_HUMAN", "id": "Q06210-1", "name": "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "aln": "MCGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGFDGGNDKDWEANACKIQLIKKKGKVKALDEEVHKQQDMDLDIEFDVHLGIAHTRWATHGEPSPVNSHPQRSDKNNEFIVIHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDNRESQ--DTSFTTLVERVIQQLEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILYRTARTQIGSKFTRWGSQGERGKDKKGSCNLSRVDSTTCLFPVEEKAVEYYFASDASAVIEHTNRVIFLEDDDVAAVVDGRLSIHRIKRTAGDHPGRAVQTLQMELQQIMKGNFSSFMQKEIFEQPESVVNTMRGRVNFDDYTVNLGGLKDHIKEIQRCRRLILIACGTSYHAGVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFLSQSGETADTLMGLRYCKERGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFALMMCDDRISMQERRKEIMLGLKRLPDLIKEVLSMDDEIQKLATELYHQKSVLIMGRGYHYATCLEGALKIKEITYMHSEGILAGELKHGPLALVDKLMPVIMIIMRDHTYAKCQNALQQVVARQGRPVVICDKEDTETIKNTKRTIKVPHSVDCLQGILSVIPLQLLAFHLAVLRGYDVDFPRNLAKSVTVE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2P2R3-1", "uniprot_id": "YM084_YEAST", "id": "A2P2R3-1", "name": "Putative glutamine--fructose-6-phosphate aminotransferase [isomerizing]", "aln": "MCGIFGYCNFLIEKTRGEIIDTLIEGLQALEYKEYDSSGISIQG---DELES----LNIYKQTGKISSLKEEIDLYN-LNKNLPFISHCGIAHTRRATHGGLRRANCHPHNSDPSNEFVVVHNGVITNFANLKALLMAKGYVFKSDTDTECIPKLYKHIYDTSIELGYNLDFHVLTNLVLKELEGSYGLLCTSSHFPDEVVAARKGSPLVIGVKGKTDMDVN-------------------------------------------------------------------------------------------------------------------------FVEVEYLDQEE--------------------------------------------------------------------DYLKLNTQTK----------------------------------------------------SSGNVLAAAPVK------------------------------------------------------------------------YNTCLR-----KSPPFVHNT-----------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****.* *: : :** **::***:*** ***: ***:*:.::* .: *: ::: *:.**:.:*.**:. : :: :: * * ****** **** .*.**:.** .***:*:***:***: :** :* :*** *:*:**** *.** *::**. . : .* .*.: *:::***::.*: .* ***.:.*.:*:****:***:.: .:..: *:: * ::* * *:*. ** . .:* :..*..* * ***. *. .::*. ", "identical_positions": 114, "similar_positions": 99, "identity": "16.26%" }, { "cls_id": "homologset.agr.SGD:S000004690", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VAW3-1", "uniprot_id": "Q9VAW3_DROME", "id": "Q9VAW3-1", "name": "glutamine--fructose-6-phosphate transaminase (isomerizing)", "aln": "MCGIFAYLNYLTPKSRQEVLDLLLQGLKRLEYRGYDSTGIAIDALNSG----EAQSIMLVKRTGKVKVLEDAVAEVCRGQDYSLPIDTHIGIAHTRWATHGVPSEVNSHPQRSDEDNSFVVVHNGIITNYKDVKTLLEKRGYVFESDTDTEVIAKLVHHLWQQHPG--YTFGELVEQAIQQLEGAFAIAFKSKHFPGECVASRRGSPLLVGIKAKTKLATDHIPILYAKAHR--------PHGQPQ-------QQAYQLLPPGDCNAEFQPLERKEVEYFFASDASAVIEHTNRVIYLEDDDVAAVKSDGTLSIHRLNKSSDDPHAREIITLKMEIQQIMKGNYDYFMLKEIFEQPESVVNTMRGRMRFDTQTVVLGGIKEYIPEIKRCRRLMLIACGTSYHSAVATRQLLEELTELPVMVELASDFLDRNTPIFRDDVCFFISQSGETADTLMALRYCKQRGALIVGVTNTVGSSICRESHCGVHINAGPEIGVASTKAYTSQFISLVMFALVMSEDRLSLQQRRLEIIDGLSQLDEHIRTVLKLNSQVQQLA-KELYEHKSLLIMGRGFNFATCLEGALKVKELTYMHSEGILAGELKHGPLALVDKEMPVLMIVLRDPVYTKCMNALQQVTSRKGRPILICEEG----DNETMSFSTRSLQIPRTVDCLQGVLTVIPLQLLSYHIAVLRGCDVDCPRNLAKSVTVE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7PLC7-1", "uniprot_id": "Q7PLC7_DROME", "id": "Q7PLC7-1", "name": "glutamine--fructose-6-phosphate transaminase (isomerizing)", "aln": "MCGIFAYLNYLTPKSRQEVLDLLVTGLKRLEYRGYDSTGVAIDSPDN-------KNIVMVKRTGKVKVLEEAIQEHFSGREYSEPVLTHVGIAHTRWATHGVPCEKNSHPHRSDDENGFVVVHNGIITNYNDVKTFLSKRGYEFESDTDTEVFAKLVHHLWKTHPT--YSFRELVEQAILQVEGAFAIAVKSKYFPGECVASRRSSPLLVGIKTKTRLATDHIPILYGKDDKKLCTDQDADSGKPQDIRPHGQSRELPVLPRSESTSEFMPLEEKEVEYFFASDASAVIEHTNRVIYLEDDDVAAVR-DGTLSIHRLKKSLDDPHAREITTLKMEIQQIMKGNYDYFMQKEIFEQPDSVVNTMRGRVRFDGNAIVLGGIKDYIPEIKRCRRLMLIGCGTSYHSAVATRQLLEELTELPVMVELASDFLDRNTPIFRDDVCFFISQSGETADTLMALRYCKQRGALIVGITNTVGSSICRESHCGVHINAGPEIGVASTKAYTSQFISLVMFALVMSEDRLSLQQRRLEILQALSKLADQIRDVLQLDSKVKELA-KDLYQHKSLLIMGRGYNFATCLEGALKVKELTYMHSEGIMAGELKHGPLALVDDSMPVLMIVLRDPVYVKCMNALQQVTSRKGCPIIICEEG----DEETKAFSSRHLEIPRTVDCLQGILTVIPMQLLSYHIAVLRGCDVDCPRNLAKSVTVE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47856-1", "uniprot_id": "GFPT1_MOUSE", "id": "P47856-1", "name": "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "aln": "MCGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGLDGGNDKDWEANACKIQLIKKKGKVKALDEEVHKQQ-DMDLDIEFDVHLGIAHTRWATHGEPNPVNSHPQRSDKNNEFIVIHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDNWESQDVSFTTLVERVIQQLEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILYRTARTQIGSTW--WGSQAER---GKDKKGSCGLSRVDSTTCLFPVEEKAVEYYFASDASAVIEHTNRVIFLEDDDVAAVV-DGRLSIHRIKRTAGDHPGRAVQTLQMELQQIMKGNFSSFMQKEIFEQPESVVNTMRGRVNFDDYTVNLGGLKDHIKEIQRCRRLILIACGTSYHAGVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLMGLRYCKERGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFALMMCDDRISMQERRKEIMLGLKRLPDLIKEVLSMDDEIQKLA-TELYHQKSVLIMGRGYHYATCLEGALKIKEITYMHSEGILAGELKHGPLALVDKLMPVIMIIMRDHTYAKCQNALQQVVARQGRPVVICDKE----DTETIKNTKRTIKVPHSVDCLQGILSVIPLQLLAFHLAVLRGYDVDFPRNLAKSVTVE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P82808-1", "uniprot_id": "GFPT1_RAT", "id": "P82808-1", "name": "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "aln": "MCGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGLDGGNDKDWEANACKIQLIKKKGKVKALDEEVHKQQ-DMDLDIEFDVHLGIAHTRWATHGEPSPVNSHPQRSDKNNEFIVIHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDNWESQDVSFTTLVERVIQQLEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILYRTG---------------------KDKKGSCGLSRVDSTTCLFPVEEKAVEYYFASDASAVIEHTNRVIFLEDDDVAAVV-DGRLSIHRIKRTARDHPGRAVQTLQMELQQIMKGNFSSFMQKEIFEQPESVVNTMRGRVNFDDYTVNLGGLKDHIKEIQRCRRLILIACGTSYHAGMATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLMGLRYCKERGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFALMMCDDRISMQERRKEIMLGLKRLPDLIKEVLSMDDEIQKLA-TELYHQKSVLIMGRGYHYATCLEGALKIKEITYMHSEGILAGELKHGPLALVDKLMPVIMIIMRDHTYAKCQNALQQVVARQGRPVVICDKE----DTETIKNTKRTIKVPHSVDCLQGILSVIPLQLLAFHLAVLRGYDVDFPRNLAKSVTVE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q06210-1", "uniprot_id": "GFPT1_HUMAN", "id": "Q06210-1", "name": "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "aln": "MCGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGFDGGNDKDWEANACKIQLIKKKGKVKALDEEVHKQQ-DMDLDIEFDVHLGIAHTRWATHGEPSPVNSHPQRSDKNNEFIVIHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDNRESQDTSFTTLVERVIQQLEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILYRTARTQIGSKFTRWGSQGER---GKDKKGSCNLSRVDSTTCLFPVEEKAVEYYFASDASAVIEHTNRVIFLEDDDVAAVV-DGRLSIHRIKRTAGDHPGRAVQTLQMELQQIMKGNFSSFMQKEIFEQPESVVNTMRGRVNFDDYTVNLGGLKDHIKEIQRCRRLILIACGTSYHAGVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFLSQSGETADTLMGLRYCKERGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFALMMCDDRISMQERRKEIMLGLKRLPDLIKEVLSMDDEIQKLA-TELYHQKSVLIMGRGYHYATCLEGALKIKEITYMHSEGILAGELKHGPLALVDKLMPVIMIIMRDHTYAKCQNALQQVVARQGRPVVICDKE----DTETIKNTKRTIKVPHSVDCLQGILSVIPLQLLAFHLAVLRGYDVDFPRNLAKSVTVE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CF18-1", "uniprot_id": "YM085_YEAST", "id": "P0CF18-1", "name": "Uncharacterized protein YMR085W", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEFYLSSDCASLARYVSKVVYLEDNDIAHIY-DGELHIHCSKIGSEDFSFRTVQKLELELSKIKKGPYDNFMQKEIYEQCETTKNVMRGRVDAFTNRVVLGGLENWLTELRRAKRIIMIASKASFHSCLAARPIFEELMEVPVNVELALDFVDRNCCIFRNDVCIFVSRSGETTDTINALNYCIKKEAVTIGVVNCSGSSISRFTHCGVHTNTGPEKGIATTKSYTSQYIALVMIALWMSEDLVSKIERRKEIIQALTIVPSQIKEVLELEPLIIELCDKKLKQHDTFLLLGRGYQFASALEGASKMKEISYVHSESILTNELGHRVLAVASDNPPIIAFATKDAFSPKIASCIDQIIERKGNPIIICNKGHKIWEQDKQKGNVVTLEVPQTVDCLQGILNVIPLQLISYWLAIKKDIGVDLPRDSAMSAPDI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*::::**.::: .:..:*::***:*:* : ** * ** : * * : .*::*:.:* ** :. ** ***:** ::. *.****: : ***::: : *::*.:*:::*.. :*:*: :*:* ::*** *:** **** **:*** :**:***:*:*:****:**: .*.** :: *: :*:.* ****.* :.**** *:*** *:*:**:****:::***:** *.:* :* :** **: .*. : . *: **.:: : :*. ..* .:.:.*::***:::*:.**** *:**::*:***.*::.** * **:... *:: : :* * ..::*: *:* *::**:: : :. . :::*::******:*.***:**::: :*: :. .** **: * *.. ", "identical_positions": 168, "similar_positions": 163, "identity": "23.7%" }, { "cls_id": "homologset.agr.SGD:S000004695", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920A7-1", "uniprot_id": "AFG31_MOUSE", "id": "Q920A7-1", "name": "Mitochondrial inner membrane m-AAA protease component AFG3L1", "aln": "---MLLRLVGAAGSRALAWPFSKLWRCGGCAGSGGTVWSSVRACGIALQGHLGRCSQQLALQGKLTSFSPRLYSKPPRGFEKFFKNKKN--------------RKSAS-PGNSVPPKKEPKNAGPG-------GDGGNRGGKGDDFPWWKRMQKGEFP-----------WDD------KDFRSLAVLGAGVAAG-FLYFYFRDPGK-EITWKHFVQYYLARGLVDRLEVVNKQFVRVIPVP----GTT--SERFVWFNIGSVDTFERNLESAQWELGIEPTNQAAVVYTTESDGS-FLRSLVPTLVLVSILLYAMRRGPMGTGRGGRG-GGLFSVGETTAKILKNNIDVR--FADVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAMLTGPPGTGKTLLAKATAGEANVPFITVNGSEFLEMFVGVGPARVRDMFAMARKHAPCILFIDEIDAIGRKRGRGHLGGQS-EQENTLNQMLVEMDGFNSSTNVVVLAGTNRPDILDPALTRPGRFDRQIYIGPPDIKGRSSIFKVHLRPLKLDGSLSKDALSRKLAALTPGFTGADISNVCNEAALIAARHLSPSVQERHFEQAIERVIGGLEKKTQVLQPSEKTTVAYHEAGHAVVGWFLEHADPLLKVSIIPRGKG-LGYAQYLPREQFLYTREQLFDRMCMMLGGRVAEQLFFGQITTGAQDDLRKVTQSAYAQIVQFGMSEKLGQVSFDFPRQGETMVEKPYSEATAQLIDEEVRCLVRSAYNRTLELLTQCREQVEKVGRRLLEKEVLEKADMIELLGPRPFAEKS-TYEEFVEGTGSLEEDTSLPEGLKDWNKGRE-----EGGTERGLQESPV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZQ14-1", "uniprot_id": "A0A8I5ZQ14_RAT", "id": "A0A8I5ZQ14-1", "name": "", "aln": "---MLLRLVGAAGTRALAWPFFKLWQCGGCAGSGGTVWSSVRACGIALQGRLGRCSQQLALQGRLTSFSPSLYSKPPK--------------------------------GTGLPPSLVPQIN-------------RTSVTRSVSLTWTE---QGEFP-----------WDD------KDFRSLAVLGAGVASG-FLYFYFRDPGK-EITWKHFVQYYLARGLVDRLEVVNKQFVRVIPVP----GTT--SEKFVWFNIGSVDTFERNLESAQWELGVEPTNQVSVVYTTESDGS-LLRSLVPTLVLVGILLYAMKRGPMGTGRGGRG-GGLFSVGETTAKILKNNIDVR--FADVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAMLTGPPGTGKTLLAKATAGEAKVPFITVNGSEFLEMFVGVGPARVRDMFAMARKHAPCILFIDEIDAIGRKRGRGHLGGQS-EQENTLNQMLVEMDGFNSTTNVVVLAGTNRPDILDPALTRPGRFDRQIYIGPPDIKGRSSIFKVHLRPLKLDESLTRDALSRKLAALTPGFTGADISNVCNEAALIAARHLSPSVQERHFEQAIERVIGGLEKKTQVLQPSEKTTVAYHEAGHAVVGWFLEHADPLLKVSIIPRGKG-LGYAQYLPREQYLYTREQLFDRMCMMLGGRVAEQLFFGQITTGAQDDLRKVTQSAYAQIVQFGMSEKLGQVSFDFPRQGETMVEKPYSEATAQLIDEEVRCLVRSAYNRTLELLTQCREQVEKVGRRLLEKEVLEKADMIELLGPRPFAEKS-TYEEFVEGTGSLEEDTSLPEGLKDWNQGRE-----ERGTEQSLQESPA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JZQ2-1", "uniprot_id": "AFG32_MOUSE", "id": "Q8JZQ2-1", "name": "Mitochondrial inner membrane m-AAA protease component AFG3L2", "aln": "MAHRCLLLWSRGGCR-RGLPP--LLVPRGCLGPDRRPCLRTLYQYATVQTASSRRS----LLRDVIAAYQRFCSRPPKGFEKYFPNGKN--------------GKKASEPKEAVGEKKEPQPSGPQ-PSGGAGGGGGKRRGKKEDSHWWSRFQKGDFP-----------WDD------KDFRMYFLWTALFWGGVMIYFVFKSSGR-EITWKDFVNNYLSKGVVDRLEVVNKRFVRVTFTP----GKTPVDGQYVWFNIGSVDTFERNLETLQQELGIEGENRVPVVYIAESDGS-FLLSMLPTVLIIAFLLYTIRRGPAGIGRTGRGMGGLFSVGETTAKVLKDEIDVK--FKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFGGQS-EQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDSALEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDAINEKHFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWYLEHADPLLKVSIIPRGKG-LGYAQYLPKEQYLYTKEQLLDRMCMTLGGRVSEEIFFGRITTGAQDDLRKVTQSAYAQIVQFGMNEKVGQISFDLPRQGDMVLEKPYSEATARMIDDEVRILISDAYRRTVALLTEKKADVEKVALLLLEKEVLDKNDMVQLLGPRPFTEKS-TYEEFVEGTGSLDEDTSLPEGLQDWNKEREKEEKKEKEKEEPLNEKVVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LN92-1", "uniprot_id": "F1LN92_RAT", "id": "F1LN92-1", "name": "", "aln": "MAHRCLLLWGRGGCR-RGLPP--LLVPSGCLGPGRRPCLRTLYQYATVQTANSRSS----LLRDVIAAYQRFCSRPPKGFEKYFPNGKN--------------GKKASESKEAVGEKKESQLSGPQ-SSGGASGGGGKRRGKKEDSHWWSRFQKGDFP-----------WDD------KDFRMYFLWTALFWSGVMIYFLFKSSGR-EITWKDFVNNYLSKGVVDRLEVVNKRFVRVTFTP----GKTPVDGQYVWFNIGSVDTFERNLETLQQELGIEGENRVPVVYIAESDGS-FLLSMLPTVLIIAFLLYTIRRGPAGIGRTGRGMGGLFSVGETTAKVLKDEIDVK--FKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFGGQS-EQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDSALEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDAINEKHFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWYLEHADPLLKVSIIPRGKG-LGYAQYLPKEQYLYTKEQLLDRMCMTLGGRVSEEIFFGRITTGAQDDLRKVTQSAYAQIVQFGMNEKVGQISFDLPRQGDMVLEKPYSEATARMIDDEVRILISEAYKRTVALLTEKKADVEKVALLLLEKEVLDKNDMVELLGPRPFTEKS-TYEEFVEGTGSLDEDTSLPEGLQDWNKEREKEKKEKKEKEEPVNEKVVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y4W6-1", "uniprot_id": "AFG32_HUMAN", "id": "Q9Y4W6-1", "name": "Mitochondrial inner membrane m-AAA protease component AFG3L2", "aln": "MAHRCLRLWGRGGCWPRGLQQ--LLVP-GGVGPGEQPCLRTLYRFVTTQARASRNS----LLTDIIAAYQRFCSRPPKGFEKYFPNGKN--------------GKKASEPKEVMGEKKESKPAATTRSSGGGGGGGGKRGGKKDDSHWWSRFQKGDIP-----------WDD------KDFRMFFLWTALFWGGVMFYLLLKRSGR-EITWKDFVNNYLSKGVVDRLEVVNKRFVRVTFTP----GKTPVDGQYVWFNIGSVDTFERNLETLQQELGIEGENRVPVVYIAESDGS-FLLSMLPTVLIIAFLLYTIRRGPAGIGRTGRGMGGLFSVGETTAKVLKDEIDVK--FKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFGGQS-EQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSINQKHFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWYLEHADPLLKVSIIPRGKG-LGYAQYLPKEQYLYTKEQLLDRMCMTLGGRVSEEIFFGRITTGAQDDLRKVTQSAYAQIVQFGMNEKVGQISFDLPRQGDMVLEKPYSEATARLIDDEVRILINDAYKRTVALLTEKKADVEKVALLLLEKEVLDKNDMVELLGPRPFAEKS-TYEEFVEGTGSLDEDTSLPEGLKDWNKERE------KEKEEPPGEKVAN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40341-1", "uniprot_id": "YTA12_YEAST", "id": "P40341-1", "name": "Mitochondrial inner membrane m-AAA protease component YTA12", "aln": "---MLLLSWSRIATKVVRRPVRFRSYYGLTHIKSLHTQYRLLNRLQENKSGNKNEDNNEDAKLNKEIPTDEEVEAIRKQVEKYIEQTKNNTIPANWKEQKRKIDESIRRLEDAVLKQESNRIQEERKEKEEENGPSKAKSNRTKEQGYFEGNNSRNIPPPPPPPPPKPPLNDPSNPVSKNVNLFQIGLTFFLLSFLLDLLNSLEEQSEITWQDFREKLLAKGYVAKLIVVNKSMVKVMLNDNGKNQADNYGRNFYYFTIGSIDSFEHKLQKAQDELDIDKDFRIPVLYVQEGNWAKAMFQILPTVLMIAGIIWLTRRSAQAAG-GSRG--GIFGLSRSKAKKFNTETDVKIKFKDVAGCDEAKEEIMEFVSFLKEPSRYEKMGAKIPRGAILSGPPGTGKTLLAKATAGEAGVPFYFVSGSEFVEMFVGVGAARVRDLFKTARENAPSIVFIDEIDAIGKARQKGNFSGANDERENTLNQMLVEMDGFTPADHVVVLAGTNRPDILDKALLRPGRFDRHINIDKPELEGRKAIFAVHLHHLKLAGEIFD--LKNRLAALTPGFSGADIANVCNEAALIAARSDEDAVKLNHFEQAIERVIGGVERKSKLLSPEEKKVVAYHEAGHAVCGWYLKYADPLLKVSIIPRGQGALGYAQYLPGDIFLLTEQQLKDRMTMSLGGRVSEELHFPSVTSGASDDFKKVTSMATAMVTELGMSDKIGWVNYQ--KRDDSDLTKPFSDETGDIIDSEVYRIVQECHDRCTKLLKEKAEDVEKIAQVLLKKEVLTREDMIDLLGKRPFPERNDAFDKYLN-----DYETEKIRKEEEKNEKRN-------EPKPSTN-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . . : . . . : : . : : . : . . ::* :* *:.. : : . . :: : : ****:.* : *::* * :* **** :*:* . .: :*.***:*:**::*:. * **.:: : .*:* *.: : : .::**::::. ::: :*.. . * .** *:*.:..:.** :: : **: * *****:*** ******.***:*.:*:.:*****:**:*:****************** *** *.****:*******.*****:* **::**.*:*******:*: * :*::.* . *:******:*******..: :**:*********** ** *******:* *. *:::** :** ***: *** : * .:**:*****:***::************ . ::: .************:*:*:::*.*.**..********** **:*::*************:* ******** : :* *.:** *** * *****:*::.* :*:**.**::***. * * :.::**.:*:* :.:: ::.: : **:*: *. :**.** :: ..: * **.: :***:. **:**** : **::*** ***.*:. ::::::: : :*. . :: *: *: : ", "identical_positions": 314, "similar_positions": 219, "identity": "36.85%" }, { "cls_id": "homologset.agr.SGD:S000004696", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZUN1-1", "uniprot_id": "A0A8I5ZUN1_RAT", "id": "A0A8I5ZUN1-1", "name": "Flavin reductase (NADPH)", "aln": "--MAVKKIAIFGATGRTG-----LTTLAQAVQAGYEVTVLVRDSSRLPSEGPQPAHVVVGDVLQAGDVDKTVAGQDAVIVLLGTGNDLSP--TTVMSEGTRNIVAAMKAHGVDKVVACTSAFLL-WDPSKVPPRLQDVTDDHIRMHKILEESGLKYVAVMPPHIG---DQPLTGAYTVTLDGRGPSRVISKHDLGHFMLRCLTTHEYDGQKTYPSHQAGGRTQGLALPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q923D2-1", "uniprot_id": "BLVRB_MOUSE", "id": "Q923D2-1", "name": "Flavin reductase (NADPH)", "aln": "--MTVKKIAIFGATGRTG-----LTTLAQAVQAGYEVTVLVRDSSRLPSEGPQPAHVVVGDVRQAADVDKTVAGQEAVIVLLGTGNDLSP--TTVMSEGTRNIVTAMKAHGVDKVVACTSAFLL-WDPTKVPPRLQDVTDDHIRMHKILQESGLKYVAVMPPHIG---DQPLTGAYTVTLDGRGPSRVISKHDLGHFMLRCLTTNEYDGHTTYPSHQYD----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30043-1", "uniprot_id": "BLVRB_HUMAN", "id": "P30043-1", "name": "Flavin reductase (NADPH)", "aln": "--MAVKKIAIFGATGQTG-----LTTLAQAVQAGYEVTVLVRDSSRLPSEGPRPAHVVVGDVLQAADVDKTVAGQDAVIVLLGTRNDLSP--TTVMSEGARNIVAAMKAHGVDKVVACTSAFLL-WDPTKVPPRLQAVTDDHIRMHKVLRESGLKYVAVMPPHIG---DQPLTGAYTVTLDGRGPSRVISKHDLGHFMLRCLTTDEYDGHSTYPSHQYQ----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N0W6-1", "uniprot_id": "A0A8M1N0W6_DANRE", "id": "A0A8M1N0W6-1", "name": "", "aln": "MSDAVRNVAIFGCTGMTG-----LATLPIAVASGYNVTVLVRDPARLPPD-HKASRVVVGDVLNKNDVKKTLEGQDAVIIILGTRNDLSP--TTMMSEGTRNIVEVMKARGIRKVVGCMSAFLL-WDRSKVPPRLVPVTEDHDRMYTVLKESGLDYIAAMPPHIAG--DKPLTEKYIVTEN-MLKGRVISKYDLGHFFVKCLSTSEWDGKTVGICGEYS----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VH72-1", "uniprot_id": "Q9VH72_DROME", "id": "Q9VH72-1", "name": "NAD(P)-binding domain-containing protein", "aln": "----MQRIAIIGGTGMTG-----ECAVDHALQKGLSVKLLYRSEKTVPERFKSKVELVKGDVTNYEDVQRVIEGVDAVAVILGTRNKLEA--TTELSRGTENLIKAMKEAKLTKFSIVMSSFLL-RPLNEVPTVFHRLNEEHQRMLDLTKACDLDWIAILPPHIA---DEPAT-AYTVLHD-EAPGRLVSKYDLGKFIIDSLEQPEHYRKVCGIGKSPKSA--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04304-1", "uniprot_id": "YMY0_YEAST", "id": "Q04304-1", "name": "UPF0659 protein YMR090W", "aln": "--MSPMKVAVVGASGKVGRLLINQLKANDSFSTPLAIVRTQDQVNYFKNEVGVDASLTDIENASVSEITDAIKAYDAVVFSAGAGGKGMERIFTVDLDGCIKVVEACEKAGIKRFVVVSALKAEDRDFWYNIKGLREYYIAKRSADREVRNSNLDYTILQPGSLELNKGTGLLQPLDKLEEKASVNYSINREDVASFIVESLLHPNATVKKTISLVNGNEPMEKFIQSL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:*:.* :* .* :. : . . :. : . :: .: . :** . *: .. * * ::: . : : :. : : : . ..*.: * : . : . :.: *:. *:: .* : : . ", "identical_positions": 14, "similar_positions": 56, "identity": "6.11%" }, { "cls_id": "homologset.agr.SGD:S000004697", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AIG5-1", "uniprot_id": "A0A8I6AIG5_RAT", "id": "A0A8I6AIG5-1", "name": "", "aln": "MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAAVAAAVASGGKSGGGGCGGGGGYSASSS----SAAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRTNIKRKTFKVDDMLSKVEKMKGEQES-------HSLSAHLQLTFTGFFHKNDKPSQNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVSEELPARRKRN---REDGE--KTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPIS---KKRATWETILDGKR--LPPFETFSQGPTLQFTLRWTGETNDKSTAPVAKPLATRNSESLHQEN-KPGSVKPAQTIAVKETLTTEMQTRKEKDTSNETRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSR-NGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVTKLR-------------------------------------------------------------------------EMQQKLEKGESAAPANEDIAEEQNGTANGFSETNSKEKALETDGVSGVPKQSKKQKL----------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80U70-1", "uniprot_id": "SUZ12_MOUSE", "id": "Q80U70-1", "name": "Polycomb protein Suz12", "aln": "MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAAVAAAAS-GGKSGGGGCGGGGSYSASSSSAAAAAAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRTSIKRKTFKVDDMLSKVEKMKGEQES-------HSLSAHLQLTFTGFFHKNDKPSQNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVSEELPARRKRN---REDGE--KTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPIS---KKRATWETILDGKR--LPPFETFSQGPTLQFTLRWTGETNDKSTAPVAKPLATRNSESLHQEN-KPGSVKPAQTIAVKETLTTELQTRKEKDNSNESRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSR-NGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVTKLR-------------------------------------------------------------------------EMQQKLEKGESATPSNEEIAEEQNGTANGFSETNSKEKALETDGVSGVPKQSKKQKL----------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15022-1", "uniprot_id": "SUZ12_HUMAN", "id": "Q15022-1", "name": "Polycomb protein SUZ12", "aln": "MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATAS-GGKSGGGSCGGGGSYSASSSSS--AAAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRTNIKRKTFKVDDMLSKVEKMKGEQES-------HSLSAHLQLTFTGFFHKNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRN---REDGE--KTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPIS---KKRATWETILDGKR--LPPFETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATRNSESLHQEN-KPGSVKPTQTIAVKESLTTDLQTRKEKDTPNENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSR-NGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVTKLR-------------------------------------------------------------------------EMQQKLEKGESASPANEEITEEQNGTANGFSEINSKEKALETDSVSGVSKQSKKQKL----------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0R1D5-1", "uniprot_id": "SZ12B_DANRE", "id": "B0R1D5-1", "name": "Polycomb protein suz12-B", "aln": "MAPQKY---------------------SAQVMNSKAN-------------------------GAVYPSSGVSSLKKPKIEQLQADHELFLQAFEKPTQIYRFLRTRNLITPVLLHRTLTFMSHRNSRTNAKRKSFKVDDLLSSVEKMKGEPES-------PSLTSHLQLTFTGFFHKNVKPCQNSENEQNSVSLEVLLVKVCHKKRKDVSCPIKQVPTGKKQVPLNPDLSQTKPGAFPSLLVSSNEFEPSNSHMVKSYSLLFRVSHTGKRDPNGFISCEADENIDVKDEIPPRRKRNSSLRGDGETTETFVAQMTVFDKNRRLQLLDGEYEVSMQQIEDCPVS---KKRATWETILDGKR--LPPFETFSQGPTLQFTLRWTADPSDPSTAPVAKPLSTRNSDTSTTES-RISTLRPAP-VAVKESVSTSMQSRIEHS-PCEPRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLSHSRFIFNYVPHPKGARIDVSINECYDGSYVGNPQDIHSQPGFAFSR-NGPVKRTAVTHILVCRPKRTKPSLSEFLESEDGEPEQQRTYVSGHNRLYFHSDSCMPLRPQEMEVDSEDERDPEWLQEKTTTQIEEFTDVNEGEKEVMKLWNLHVMKNGFIADNQMSQASMLFVEICGPHIIRRNLCRNFLLHLVNLHDFNLVTIATIDQAMARLK-------------------------------------------------------------------------EIEESFPELEAGQ-------ESLDATCNGHSLS---------LGFSLHGKCTKLES-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6DC03-1", "uniprot_id": "SZ12A_DANRE", "id": "Q6DC03-1", "name": "Polycomb protein suz12-A", "aln": "MAPQKHG------------SGGNGFYGNSASKAANGG-------------------------AHASSGVVMTSVKRLKMEQIQADHQLFLEAFEKPTQIYRFLRTRNLITPIFLHRSLTYMSHRNSRTNSKRKSFSLNDLLFKVEKSKVDPES-------HNLASNLQLTFTGFFHKTEKQLQNSENEENSVSVEVLLVKLCHKKRKDVTCPVKQVPTGKKQVPLNPDISPTKLGAFPTLVVPSHEFEPVNSNTVKSYSLLFRASRPWGREHNGMTTRDT----NVIEELSNRKKRYCSHQDDGE--TTFVAQMTVFDKNRRLQLLDGEYEVSMQEIEESPVG---KKRATWETILDEKW--VPPFETFSQGPTLQFTLRWTNDTADKATAPVAKPLATRNSESSTVDSSKTSNIKPPQAVAVNDSLGTDLPVRREQT-HIEPCQKLHVYYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLSHSRFIFNYVPHPKGARIDVSINECYDGSYVGNPQDILCQPGFAFSR-NGPVKRTPVTQILVCRPKRSKPSLSEFLEPEDGEQEQQRTYISGHNRLYFHSDSCTPLRPQEMEVDSEDERDPDWLREKTAMQIEEFTDVNEGEKEIMKLWNLLVMKHGFIADNQMNQACMSFVEQHGTIMVEKNLCRNALLHLINMHDFGLITTATIDKAMTHLR-------------------------------------------------------------------------DLTQQSIAQH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NJG9-1", "uniprot_id": "SUZ12_DROME", "id": "Q9NJG9-1", "name": "Polycomb protein Su(z)12", "aln": "MAPAKKREKDSN----PDGSAANGIIGLTHGAPDASN---------------------------AGSTVPPTAEGQVKLNGHQQEQELFLQAFEKPTQIYRYLRNRHETNPIFLNRTLSYMKERMSRNNKKRISFQVNSMLESITQKSEAVSQNYLHVIYDSLHEKLPARLDNESGEDLLQEQLLCEAGESVSVETTLYKITRSKRKDSTLDFQELLSKCSQIVYNP---KDRVGEHATISIPLQTMRPMG-EQHTLYKLLFRIKVLSPSTCN-----------DENAETPPNKRSR-----PNE--KMFGSELILYEKSS-GFITEGEYEAMLQPLNSTSIKSFSPKKCTWETMPDSYIPLSLTYDVYQQSPMLKFHLTLSNEQLPEMISAPELQRYVQHLDAVAEMNYNNNNYNNNNNCSGLKNGSGGGNSTVCKT----TPEHIQIVYNFMYSNNTRQQTEYTQELNCPWCGLDCLRLYALLKHLKLCHARFNFTYQPAGSGARIDVTINDAYDGSYAGSPYDLAGPSGSSFARTCGPVRRTSVTSLMVCRPRRQKTCLDEFLELDEDEISNQRSYITGHNRLYHHTETCLPVHPKELDIDSEGESDPLWLRQKTIQMIDEFSDVNEGEKELMKLWNLHVMRHGFVGDCQLPIACEMFLDAKGTEIVRKNLYRNFILHMCSLFDYGLIAAETVYKTVQKLQGLLSKYAAGQELMQRQREEQLKYWLDVGMHKKQEDPKTLKSPQKPAPPADQASTSSASTSGSGSGSSSMQPPKRMPAHLKRGSAASSPGVQSKGTENGTNGSNSSSSNSKNVAKKSADQPLSTLANTRERRSEYGQKRNVSGSRLAATPASKRKLSSKDNTVLNKRQRYSDGSPGTGIGNGHGGGSGSGANRNKSNNHSLPATSNNASSSSSNSKRAIARRRSTSERTKASGSTGGGAGGVRTRLSVPAKYERR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32832-1", "uniprot_id": "RSC7_YEAST", "id": "P32832-1", "name": "Chromatin structure-remodeling complex subunit RSC7", "aln": "------------------------------------------------------------------------------------------------------------MSDSEGGLASEVEHEKRSRSTSNRPNYAIDTEDLDIDENDENEDD----------------------DYREEEANEGVNEEEISDEEEQINKSGRNKRRHVDE--EEDLSEDKGVTRSRNRSKFKKPVFPGIDDAEENLNPLK-VVNEEYVLPDDPEGETKITADG--------------DLLGGR-------------EFLVRTFTLTEKGNRKFMLATEPARIVGFRDS---------------------------YLFFQTHPNLYKFILNQTQKNDLIDRGVLPYSYRNRQIALVTARGVFKEFGAKIIRGGKHITDDYYASELRT-------KGNVIEGKLAGDPIDKSARALETMMYPASENGINPAKNQVEFFEHRPHGHMSNSNIIASGSKLSSTN-----WLYQHSAACSRFNSDLFYDR----------VKVLLVDQQGLRDAYTNILHIPES---TQSTTVLGWRRSKNDSPSDTSIVYETVIHDNDLNKPKTGLSEIPKEIYEDVVDEDVLR---------------AITEQQNFEKCNEYI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: **.. :* .: :: .: : . .. : : * : * :.**:. .: : . : . : .. : . . :.* * * : : : : : : :*. : * : :. : * : : . :: : . . : : .: : .: :.:. : : * . . ::.:: . . .*:::. : * .. .. : * . ::: : : . ::*. :. * : * .* .: : .: : : *.: : * : . ::. * : . : : * . :: ", "identical_positions": 25, "similar_positions": 127, "identity": "2.61%" }, { "cls_id": "homologset.agr.SGD:S000004698", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RKI0-1", "uniprot_id": "WDR1_RAT", "id": "Q5RKI0-1", "name": "WD repeat-containing protein 1", "aln": "------MPYEIKKVFASLPQVERGVSKILGGDPKGDNFLYTNGKCVILRNIDN-----PAVADIYTEHAHQVVVAKYAPS--GFYIASGDISGKLRIW------DTTQKEHILKYEYQPFAGKIKDIAWTEDSKRIAVVGEGREKFGAVFLWDTGSSVGEITGHNKVINSVDIKQNRPYRLATGSDDNCAAFFEGPPFKFKFTIGDHSR---FVNCVRFSPD-GNRFATASADGQIFIYDGKTGEKVCALGG-SKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTFPMG-SNVLDQQLGCLWQKD-HLLSISLSGYINYLDKNNPSKPLRVIKGHSKSIQCLTVHKNGGKSYIYSGSHDGHINYWDSETGENDSFSGKGHTNQVSRMTVDESGQLVSCSMDDTVRYTNLTLRDYSGQGVVKLDVQPKCVAVGPG-GYTVVVCIGQIVLLKDQKKCFSIDNPGYEPEVVAVHPGGDTVAVGGSDGNVRVYSILGATLKDEGKLLEAKGPVTDLAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHH-AKIVCLAWSPDNE----------HFASGGMDMMVYVWTLSDPETKVKIQDAHRLHHVSSLAWLDEHTLVTTSHDASVKEWTITY-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88342-1", "uniprot_id": "WDR1_MOUSE", "id": "O88342-1", "name": "WD repeat-containing protein 1", "aln": "------MPYEIKKVFASLPQVERGVSKILGGDPKGDHFLYTNGKCVILRNIDN-----PAIADIYTEHAHQVVVAKYAPS--GFYIASGDISGKLRIW------DTTQKEHLLKYEYQPFAGKIKDIAWTEDSKRIAVVGEGREKFGAVFLWDTGSSVGEITGHNKVINSVDIKQTRPYRLATGSDDNCAAFFEGPPFKFKFTIGDHSR---FVNCVRFSPD-GNRFATASADGQIFIYDGKTGEKVCALGE-SKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTFPMG-SNVLDQQLGCLWQKD-HLLSISLSGYINYLDKNNPSKPLRVIKGHSKSIQCLTVHRNGGKSYIYSGSHDGHINYWDSETGENDSFSGKGHTNQVSRMTVNESEQLVSCSMDDTVRYTNLTLRDYSGQGVVKLDVQPKCVAVGPG-GYTVVVCIGQIVLLKDQKKCFSIDNPGYEPEVVAVHPGGDTVAVGGTDGNVRVYSILASTLKDEGKLLEAKGPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHH-AKIVCLAWSPDNE----------HFASGGMDMMVYVWTLSDPETKVKIQDAHRLHHVSSLAWLDEHTLVTTSHDASVKEWTITY-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75083-1", "uniprot_id": "WDR1_HUMAN", "id": "O75083-1", "name": "WD repeat-containing protein 1", "aln": "------MPYEIKKVFASLPQVERGVSKIIGGDPKGNNFLYTNGKCVILRNIDN-----PALADIYTEHAHQVVVAKYAPS--GFYIASGDVSGKLRIW------DTTQKEHLLKYEYQPFAGKIKDIAWTEDSKRIAVVGEGREKFGAVFLWDSGSSVGEITGHNKVINSVDIKQSRPYRLATGSDDNCAAFFEGPPFKFKFTIGDHSR---FVNCVRFSPD-GNRFATASADGQIYIYDGKTGEKVCALGG-SKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVSVNSVVSTFPMG-STVLDQQLGCLWQKD-HLLSVSLSGYINYLDRNNPSKPLHVIKGHSKSIQCLTVHKNGGKSYIYSGSHDGHINYWDSETGENDSFAGKGHTNQVSRMTVDESGQLISCSMDDTVRYTSLMLRDYSGQGVVKLDVQPKCVAVGPG-GYAVVVCIGQIVLLKDQRKCFSIDNPGYEPEVVAVHPGGDTVAIGGVDGNVRLYSILGTTLKDEGKLLEAKGPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHH-AKIVCLAWSPDNE----------HFASGGMDMMVYVWTLSDPETRVKIQDAHRLHHVSSLAWLDEHTLVTTSHDASVKEWTITY-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VU68-1", "uniprot_id": "WDR1_DROME", "id": "Q9VU68-1", "name": "Actin-interacting protein 1", "aln": "MAQPQPPAYENKNIYATLPRTQRGQPIVLGADPKGKNFLYTNGNSVIIRNIEN-----PAIADVYTEHSCAVNVAKYSPS--GFYIASGDASGKIRIW------DTVNKEHLLKNEFQPIAGPIKDISWSPDNQRIVAVGEGRERFGHVFMSETGTSVGEISGQSKSINSADFRPARPFRIVTGSEDNTIAVFEGPPFKFKMTKQDHSR---FVQAVRYSPD-GKFFASAGFDGKVFLYDGTSSELVGEFG--SPAHKGGVYALAWKPDSTQLLTCSGDKTCRLWTVESRELVSEFVMG-TTVDDQQVSCLWQGD-NLITVSLSGVITYLNVADPSKPLRVVKGHNKPITVLGLSDD--RSTIYTGSHDGVVTNWNSGSGTNDRITGTGHGNQINGIAAWG-DFVYTCGIDDSLRQFSVEGNSYTDY-VVKLNCQPRGLAILRNENIIALACIKELTLVQDQKKIFSLP-IKYEASSIAVNADTSDVAVGGDDQKLHIYTLKGGVLEPK-VELDHLGAVTDVSYSPDLKYLVACDAHRKVVLYSVEEYKPAHNKEWGFHSARVNTVAWSPNSL----------LVASGSLDTTIIIWSVANPAKHTIIKNAHPQSQITRLVWLDNNTVISTGQDCNTKVWHVENI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46680-1", "uniprot_id": "AIP1_YEAST", "id": "P46680-1", "name": "Actin-interacting protein 1", "aln": "-----MSSISLKEIIPPQPSTQRNFTTHLSYDPTTNAIAYPCGKSAFVRCLDDGDSKVPPVVQFTGHGSSVVTTVKFSPIKGSQYLCSGDESGKVIVWGWTFDKESNSVEVNVKSEFQVLAGPISDISWDFEGRRLCVVGEGRDNFGVFISWDSGNSLGEVSGHSQRINACHLKQSRPMRSMTVGDDGSVVFYQGPPFKFSASDRTHHKQGSFVRDVEFSPDSGEFVITVGSDRKISCFDGKSGEFLKYIEDDQEPVQGGIFALSWLD-SQKFATVGADATIRVWDVTTSKCVQKWTLDKQQLGNQQVGVVATGNGRIISLSLDGTLNFYELG-HDEVLKTISGHNKGITALTVN------PLISGSYDGRIMEWSSSSMHQD------HSNLIVSLDNSKAQEYSSISWDDTLKVNGITKHEFGSQ---------PKVASANNDGFTAVLTNDDDLLILQSFTGDIIKSVRLNSPGSAVSLSQNYVAVGLEEGNTIQVFKLSDLEVSFDLKTPLRAKPSYISISPSETYIAAGDVMGKILLYDLQS-REVKTSRWAFHTSKINAISWKPAEKGANEEEIEEDLVATGSLDTNIFIYSVKRPMKIIKALNAHKDG-VNNLLWETPSTLVSSGADACIKRWNVVLE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . *:: .. * .:*. . :. **. . : *. *:..::* ::: *.:.:. . : * ..*::* . *:.*** ***: :* :: . * :* *:* :** *.**:* :.:*: .*****:.** .: ::*.*:**::*:.: **: .:: ** * * .:*. ..::******. : * : **. *.:*** *: . :.. * :: :**.:.* : : . . .**::*::* * :: : ..* * ::* * . *. : :. : :**:. : : .::::**.* :.: : .: *:.:.**.* * * : : :**:** : *.* : :* * * : : : . **::: .: ..: . :* . . .: : *: :. . : :. ** . . **:* : : . . : :: * . ::.. *. : ::.: . :. :..* ::: ::*.* . .*:*.:* : :::: * . :** :. * * *::::. *. * * : ", "identical_positions": 124, "similar_positions": 226, "identity": "19.22%" }, { "cls_id": "homologset.agr.SGD:S000004699", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C7V3-1", "uniprot_id": "UTP15_MOUSE", "id": "Q8C7V3-1", "name": "U3 small nucleolar RNA-associated protein 15 homolog", "aln": "-MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQLPYNYAVTASSRIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDING-RAPLRQFEGHTKAVHTVDFTADNYHVVSGA-DDYTVKLWDIPNSKEILTFKE-HSDYVRCGCASKLNPDLFVTGSYDHTVKIFDART-NKNVL-CVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSG-----QRLLSGSLDRKVKVYST-TSYKVVHSFDYAASILSLALSH----QDETIVVGMTNGILSVKHRKSEAKKTSLPRRRR------PAYRTFIKGK--NYLKQRDDIMVSRPAK--KHLEGYDKDLKSFRVSQALDRVLEPKCVIRTPEVTVSIIKELTRRGVLANALAGRDEKEVTRVLNFLIRNLSQPRFAPVLINAAEIIIDIYLP-VIGQSSVVDKKFIVLQELVEKEIDYQRELLETLGMMDMLFATMTRNDSDPVPEHVPAELPEEKTESPTQPSDTDKNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2RRU3-1", "uniprot_id": "UTP15_RAT", "id": "A2RRU3-1", "name": "U3 small nucleolar RNA-associated protein 15 homolog", "aln": "-MAGYKPVVIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISG-RAPLRQFEGHTKAVHTVDFTADKYHVVSGA-DDYTVKLWDIPNSKEILTFKE-HSDYVRCGCASKLNPDLFVTGSYDHTVKMFDART-NKNVL-CVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSG-----QRLLSGSLDRKVKIYST-TSYKVVHSFDYAASILSLALSH----QDETVVVGMTNGILSVKHRKSEAKKESLPRRRR------PAYRTFIKGK--IYTKQRDDIVVTRPAK--KHLEWYDRDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIIIDIYLP-VIGQSSVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMTRNGSAPVWEHVPAELPEEKTESPRQPSDTDKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TED0-1", "uniprot_id": "UTP15_HUMAN", "id": "Q8TED0-1", "name": "U3 small nucleolar RNA-associated protein 15 homolog", "aln": "-MAGYKPVAIQTYPILGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGRLLVAGSEDGGVQLFDISG-RAPLRQFEGHTKAVHTVDFTADKYHVVSGA-DDYTVKLWDIPNSKEILTFKE-HSDYVRCGCASKLNPDLFITGSYDHTVKMFDART-SESVL-SVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSG-----QRLLSGSLDRKVKVYST-TSYKVVHSFDYAASILSLALAH----EDETIVVGMTNGILSVKHRKSEAKKESLPRRRR------PAYRTFIKGK--NYMKQRDDILINRPAK--KHLELYDRDLKHFRISKALDRVLDPTCTIKTPEITVSIIKELNRRGVLANALAGRDEKEISHVLNFLIRNLSQPRFAPVLINAAEIIIDIYLP-VIGQSPVVDKKFLLLQGLVEKEIDYQRELLETLGMMDMLFATMRRKEGTSVLEHTSDGFPENKKIES----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZW33-1", "uniprot_id": "UTP15_DANRE", "id": "Q7ZW33-1", "name": "U3 small nucleolar RNA-associated protein 15 homolog", "aln": "-MASFKPTKVLSYPKLGEKVTEETLYWKNYKPPVQIKEFGAVSKIDFSPLPPHNYAVTASTRVHIYGLHSQEPIRNFTRFHDTAYGGSFRGDGKLLVAGSEEGLIRLFDIGG-RVSLRQFKGHSKAVHATSFLSDGFRVLSGS-DDLTCRVWDVASAVELSSITE-HTDYIRAIAPSKLNPDVFVTGSYDHTVKMFDVRS-GNSVM-TMQHGQPVECVLLYPSEALLVSTGGRYVKVWDLLKGGQQLVSLKNHHKTVTCACLSSS------NKLLTASLDRHVKVYN--SSYKVVHNFDCASSILSLAVAP----DDEAVAVGMTNGVLSIRHRKHKEEKEALTGRRKRG----PSYRFFVKGK--NFVPRQDDFLVSKPVR--QHLQKYDKQLKRFEVSKALDTALETWTRTTKPEVTVAVIMELNRRGTLKNALAGRDEVSLTKILNFLLKHITDPRFSRPLLTVGDIVLDLYQQ-VIPQSPVVERLLQRLYEILGREAELQQELLQVLGILDTLFASLMPRKEVASFGAAAAAQESQLQAA-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4Z9-1", "uniprot_id": "Q9W4Z9_DROME", "id": "Q9W4Z9-1", "name": "U3 small nucleolar RNA-associated protein 15 homolog", "aln": "MQNSFLPLNTRRFRQRAQVETPDTVYWDRLAKPELLKEHNTIDYLDFSPSDPDNFVVTCSVRVQIYNLVTMLVVKNLSRFQKTAYGATFRQDGRLLAAGDEEGHVKLFDTTS-RNILRLFKGHTAPVHRTFFTADKLQLASFG-DDKSVRLWDVANEKVVQTYEDTHTDYVRAGAMHPQAGHMFVSGGYDGKIKLYDTRA-ETAVQRTLDHGAPVESMLFLPNGSIFVSAGGSQVRVWDLISGCRLLTMMSQHHKTVTCLRLGSDG-----RRLLSGGLDRHVKIYDV-STYKTVHTLTYPNAVVSMAVAD----GDQAVVAGMVDGLVSIRRMMVDSKPSHLKKIRAD-----RARKYFVSTKRTNNTQEVDHTIKDHVKG--PGLKSYDVHLRQFNHKKALDDVMNAQKMQYQPELIVAVITDLLHRGSLGKALTGRHEAALVRFIDFICNHLGEVRFMRPLMMAASTVLDVFEQRLVAYSQKLMKALQRLSLAMQEEVRLTAELMRMKGAVDMLIGISMDNSEVAHKPTYVETKTPKMHPSVAAQNYVVLVE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04305-1", "uniprot_id": "UTP15_YEAST", "id": "Q04305-1", "name": "U3 small nucleolar RNA-associated protein 15", "aln": "MSTARPRIITSKAPLLPQQTTPEQRYWRQYTSAQLVKEHNSVTHISFNPQHPHDFAVTSSTRVQIFSSRTRQVIKTFSRFKDVVYSASFRSDGKLLCAGDATGLVSVYDSYNPRTILLSINASTHPTHVTKFHTQDNKILATASDDRVTRLWDISNAYEPQLELTGATDYVRTLSFIPAAPHLVATGSYDGLIRLYDTRSSGSTPIYSLNHDQPVENVIAVSP-TQIVSCGGNNFKVWDLTSN-KKLYERGNFNKAVTCLDYVENFDSPMQSALIASSLDGHVKVFDPLDNFQVKFGWKFSGPVLSCAVSPSTAQGNRHLVAGLSSGLLAIRTKKKEKRSSDKENAPASFNKNAKSNNFQRMMRGSEYQGDQEHIIHNDKVRSQRRMRAFERNINQFKWSEALDNAFVPG---MAKELTLTVLQELRKRGKVRVALYGRDESTLEPLLNWCLKGIEDVRSASIVADWVAVVLELYGN-TLESSPVLQELMIDLKTKVRHEIHKSKEAQRIEGMLQLLTS------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * : ** . . :**..:: :.*.* * ::.**.* *::*:. : ::.::**:...* .:** **:** **. * : ::* . * * ::. : ..* . * :: :: : . ** ::**:.. :**:* . .:. :*.** ::::*.*: ::*. *** :: . :** ** .:***: .. : * :.:*:*** .. *::..** :**::. .::. . . .::* *:: :. :..*: .*::::: . . : . : :. : :. :: .:. *. .:*** .: . *: :::: :* :** : ** **.* : .::: . : : * : ::::: : * : . : * : .* * . * :: * . ", "identical_positions": 87, "similar_positions": 175, "identity": "15.68%" }, { "cls_id": "homologset.agr.SGD:S000004703", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PTB3-1", "uniprot_id": "E9PTB3_RAT", "id": "E9PTB3-1", "name": "Mitochondrial GTPase 1", "aln": "--MRLWPQAWS-AVGAAWRECFPLQGHDV-ARWFPGHMAKGLKKMQSSLKLVDCVIEVHDARYIPFSGRNPLFQELLG---LKPHLLVLNKMDLADLTE--QQKIVQHLEEKG--LRNVIFTNCIK--DENIKQIIPKVTELIGCSYRYHRAENPEYCIMVVGVPNVGKSSLINSLRRQHLRTG-------KAARVGGEPGITRAVTSRIQVCERPL-----MFLLDTPGVLAP-RIQSVETGLKLALCAACLAGTVLDHLVGEETMADYLLYTLNRHGLFGYVQHYALAS---ASDHIEWVLKNVAIKLGKTRKVKVLTGTGNVNVIQPDYAIAARDFLR----TFR------SGRLGQVMLDRDIIPAC-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2R6-1", "uniprot_id": "MTG1_MOUSE", "id": "Q8R2R6-1", "name": "Mitochondrial ribosome-associated GTPase 1", "aln": "--MRLWPQAWG-AVRGAWRECFPLQGHDV-ARWFPGHMAKGLKKMQSSLKSVDCVIEVHDAR-IPFSGRNPLFQELLG---LKPHLLVLNKMDLADLTE--QQKIVQRLEEKG--LSNVLFTNCVK--DENIKQIVPKVMELIRCSYRYHRAETPEYCIMVVGVPNVGKSSLINSLRRQHLRTG-------KAARVGGEPGITRAVTSRIQVCERPL-----VFLLDTPGVLAP-RIESVETGLKLALC-----GTVLDHLVGEETMADYLLYTLNRHGLFGYVQHYALAS---ACDQIEWVLKNVAIKLRKTRKVKVLTGTGNVNVIQPDYAMAARDFLR----TFR------SGLLGQVMLDRDIIPAC-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BT17-1", "uniprot_id": "MTG1_HUMAN", "id": "Q9BT17-1", "name": "Mitochondrial ribosome-associated GTPase 1", "aln": "--MRLTPRALCSAAQAAWRENFPLCGRDV-ARWFPGHMAKGLKKMQSSLKLVDCIIEVHDAR-IPLSGRNPLFQETLG---LKPHLLVLNKMDLADLTE--QQKIMQHLEGEG--LKNVIFTNCVK--DENVKQIIPMVTELIGRSHRYHRKENLEYCIMVIGVPNVGKSSLINSLRRQHLRKG-------KATRVGGEPGITRAVMSKIQVSERPL-----MFLLDTPGVLAP-RIESVETGLKLALC-----GTVLDHLVGEETMADYLLYTLNKHQRFGYVQHYGLGS---ACDNVERVLKSVAVKLGKTQKVKVLTGTGNVNIIQPNYPAAARDFLQ----TFR------RGLLGSVMLDLDVLRGHPPAETLP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PXJ5-1", "uniprot_id": "A0A8M9PXJ5_DANRE", "id": "A0A8M9PXJ5-1", "name": "Mitochondrial GTPase 1", "aln": "--MRIYHSLLN---AAKFRSVFDFGERDV-THWFPRHMAKGLKQMRANLRNVDCIIEIHDAR-IPFSGRNSSFQESLD---VRPHLLVLNKMDVADISK--KQSILKQFEREG--VKNVLFTDCLRQHDENVKKIVPLVSKLIESTSRFHREEERCYCLMVIGVPNVGKSSLINALRRTYLKKG-------KASKVGAEPGITKAVLTKIQVCERPI-----IHLLDTPGVLPP-RIENIETGMKLALC-----GTVLDHLVGEDVIADFLLFSLNRLERFSYVEKYSLEE---PCDDIQHVLKCIAVKLGKTRRVKAITGVGNITVQLPDYSAAAYDFIR----AFR------KGELGKVMLD--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCU5-1", "uniprot_id": "MTG1_DROME", "id": "Q9VCU5-1", "name": "Mitochondrial ribosome-associated GTPase 1", "aln": "-----MAAQLN-----PFRNAFRLPSKQR-INWFPGHMTKGMRQIQQKLRNVDCIVEIHDAR-IPLAGRNSQFFDTITGSGVKPHILVLNKVDLLGAKQ--QKSVLQQLRRQQPELQHILFTNCKDQRNNGVLDILPLATRLVSESSRFNRTQAAEHNLMIIGVPNVGKSSVINVLRNVHLKKK-------SAARVGAEAGITRSVGERIKIQENPP-----VYMIDTPGILQP-SIKDDEMGMKLALV-----GCLPDHIVGEDLIADYLLYWLNSHRKYDYVEMLKLSSG--PSDDISAVLAEYAHREELFHKVKQYDGR--VEVMT-NLLAAARKFIH----FFR------SGQLGHMNLDEPSGFR--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03151-1", "uniprot_id": "MTG1_YEAST", "id": "Q03151-1", "name": "Mitochondrial GTPase 1", "aln": "MHINVRGTRKIISNVSSFTPRYEFPKYSMPLTDFKGHQVKALKTFEKLLPQMNMIIELRDIR-APLSTRNVVFDRIARKEHDVMKLVVYTRKDLMPGNKPYIGKLKNWHEELG---EKFILLDCRN--KTDVRNLLKILEWQNYELETNGGYLPMGYRALITGMPNVGKSTLINSLRTIFHNQVNMGRKFKKVAKTGAEAGVTRATSEVIRVTSRNTESRNEIYLIDTPGIGVPGRVSDHNRMLGLALC-----GSVKNNLVDPIFQADYLLYLMNLQNLNDGRTELYPGSTNSPTNDIYDVLRRLQVNKSQNEKSTAIEWTNKWRLHGKGIIFDPEVLLNNDEFSYKNYVNDQLEKLGDLSYEGLSNKLKGNPNQVF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . * * .*.:: :. * :: ::*::* * *:: ** * :::* .: *: .: .: : . :.:: :* . .: .:: : :: *:******::** ** . . ..::.*.*.*:*::. *:: .. :.::****: * :.. : : *** * : :::*. **:**: :* . . . :.: ** . .: . : . . ::. :: ** : : ", "identical_positions": 49, "similar_positions": 102, "identity": "12.96%" }, { "cls_id": "homologset.agr.SGD:S000004705", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "X2JAD3-1", "uniprot_id": "X2JAD3_DROME", "id": "X2JAD3-1", "name": "glucose-6-phosphate 1-epimerase", "aln": "MATTAAAMAATSVVVLDRGNNTTCTINLHGATVVSWRVNNQEQLFVSKLASFDGKKAIRGGIPFVFPQFG------AWSFGPQHGFARITRWHLERPPDRLHNGDVEAIFSLMDNDFTRSIWNYQFRITYRLILREKELHFHIGVYNPSKELSFTFNMLLHTYLKVPDVRRCQITGLQGCHFIDKTRENALYQEGREVVTVNEWTDRIYQHTPQEHVITNVVSGRKMR-LHKYNFPDTVIWNPWIDRSREMSDFGDDE-FPNMLCVEAGNVTSPVILLPGTAFEASQILQQFKCPYTIDPSSCRKKNYLTNFLQYD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03161-1", "uniprot_id": "YMY9_YEAST", "id": "Q03161-1", "name": "Glucose-6-phosphate 1-epimerase", "aln": "--MPIKETDKEVVLTHPADETTSVHILKYGATVYSWKLKSEEQLWLSTAAKLDGSKPVRGGIPLVFPVFGKNSTDEHLSKLPQHGLARNSTWEFLGQTKENPPTVQFGLKPEIANPELTKLWPMDYLLILTVELGSDYLKTAIEVENTSSSKELKFNWLFHTYFRIEDIEGTMVSNLAGMKLYDQLLK-ESYVDKHPVVTFNQETDVIYQNVSAERAIQIVDKGVQIHTLKRYNLPDTVVWNPWIEKSQGMADFEPKTGYQQMICIEPGHVHDFISLAPGKKWNAYQLLCKEELKYQAIQ----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:. .:.*: * :**** **:::.:***::*. *.:**.*.:*****:*** ** * ****:** : *.: ... .: . : * .:* :: : : * .. *: * * *.*.. .:.** *:***::: *:. ::.* * :: *: : * : : ***.*: ** ***:.. *:.* * .* ::: *::**:****:*****::*: *:** . : :*:*:*.*:* . : * **. ::* *:* : : * ", "identical_positions": 95, "similar_positions": 97, "identity": "30.06%" }, { "cls_id": "homologset.agr.SGD:S000004707", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99KU1-1", "uniprot_id": "DHDDS_MOUSE", "id": "Q99KU1-1", "name": "Dehydrodolichyl diphosphate synthase complex subunit Dhdds", "aln": "------------------------------------MSWIK-----EGELSLWERFCANIIKAG-PVPKHIAFIMDGNRRYAKKCQVERQEGHTQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLLDLARQKFSCLMEEQEKLQK--HGVCIRVLGDLHLLPLDLQEKIAHAIQATKNYNKCFLNVCFAYTSRHEIANAVREMAWGVEQGLLEPSDVSESLLDKCLYSNHSPHPDILIRTSGEVRLSDFLLWQTSH-SCLVFQPVLWPEYTFWNLCEAILQFQRNHGALQ-KARDMYAEERKRRQLERDQAAVTEQLLREGLQASGDAQLRRTRLHKLSTKREERVQGFLKALELKRANWLALWGTASA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U2T2-1", "uniprot_id": "Q5U2T2_RAT", "id": "Q5U2T2-1", "name": "Alkyl transferase", "aln": "------------------------------------MSWIK-----EGELSLWERFCANIIKVG-PVPKHIAFIMDGNRRYAKKCQVERQEGHTQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLLDLARQKFSCLMEEQEKLKK--HGVCIRVLGDLHLLPLDLQKKIAQAVQATKNYNKCFLNVCFAYTSRHEITNAVREMAWGVEQGLLEPSDVSESLLDQCLYSNHSPQPDILIRTSGEVRLSDFLLWQTSH-SCLVFQPVLWPEYTFWNLCEAILQFQMNHSALQQKARDMYAEERKRHQLERDQAAVTEQLLREGLQANGDAQLRRTRLHKLSAKREERVRGFLQALNLKRADWLALWGTASA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86SQ9-1", "uniprot_id": "DHDDS_HUMAN", "id": "Q86SQ9-1", "name": "Dehydrodolichyl diphosphate synthase complex subunit DHDDS", "aln": "------------------------------------MSWIK-----EGELSLWERFCANIIKAG-PMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRLMEEKEKLQK--HGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSH-SCLVFQPVLWPEYTFWNLFEAILQFQMNHSVLQ-KARDMYAEERKRQQLERDQATVTEQLLREGLQASGDAQLRRTRLHKLSARREERVQGFLQALELKRADWLARLGTASA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3M6-1", "uniprot_id": "Q9W3M6_DROME", "id": "Q9W3M6-1", "name": "Alkyl transferase", "aln": "------------------------------------MSWVS-----DYKYTWTERIAMRTLRACGYIPHHVAFVMDGNRRFARSQQIDKIEGHSRGFEKLADCLRWCLDVGVREVTTFAFSIENFKRSNEEVEGLFNLAREKFARLLEETARLDE--HGIRIRVIGNIELLPHDLQKLVASAMLSTERNDKLFLNVAFAYTSRDEITQAVETILRHGSQDLAG-EDISERLLEECLYTRHSPPPDLVFRTSGETRLSDFMMWQLST-SVLYFSNVLWPQITFWHFLASILAYQRDRWQLD----DFRRAER----------------------------MQSCQLAKATDFYSERVQNFLTTIDEDRRKLLVRLAAN--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03175-1", "uniprot_id": "SRT1_YEAST", "id": "Q03175-1", "name": "Dehydrodolichyl diphosphate synthase complex subunit SRT1", "aln": "MKMPSIIQIQFVALKRLLVETKEQMCFAVKSIFQRVFAWVMSLSLFSWFYVNLQNILIKALRVG-PVPEHVSFIMDGNRRYAKSRRLPVKKGHEAGGLTLLTLLYICKRLGVKCVSAYAFSIENFNRPKEEVDTLMNLFTVKLDEFAKRAKDYKDPLYGSKIRIVGDQSLLSPEMRKKIKKVEEITQDGDDFTLFICFPYTSRNDMLHTIRDSVEDHLENKSPRINIRK-FTNKMYMGFHSNKCELLIRTSGHRRLSDYMLWQVHENATIEFSDTLWPNFSFFAMYLMILKWSFFSTIQKYNEKNHSLFEK---------------------------------IHESVPSIFKKKKTAMSLYNFPNPPISVSVTGDE-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*: . :.: . ::. :*.*::*:******:*:. :: :** * .* * * :*: *:.:*******:*.:.**: *::* *: : :. .. :* **::*: **. :::: : . *: :. * :.*.****.:: :::. :. :: : : :: :* ::::****. ****:::** : : *. .***: :*: : ** :. . : *: : : :: : : : . . ", "identical_positions": 64, "similar_positions": 104, "identity": "16.89%" }, { "cls_id": "homologset.agr.SGD:S000004708", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R037-1", "uniprot_id": "WDR44_RAT", "id": "Q9R037-1", "name": "WD repeat-containing protein 44", "aln": "---MMP----------LKMCTWGGSYPVG---------------SPGKVGLLSFKETKNTGNKAGN---ESPVQELRQDVSKKIIECIIE--------------ESQKVLQLEDD-------SLDSKGKG----LSDQATASHSVAGTEFSNIPGLLAIQHE------------LQQGSRKADSQNAAEETE--LETQKCFPSDNNCEKSEKTEDETNN--------LTEVSSADQLDASKLETEILNKEAVEVKEG-DVVNP----ASSDALSTKDFAAVEEVAPAKPPR----------------HLTPEPD--------------------------------------------IVASTKKPVPARP--PPPTNFPPPRPPPPSRPAPPPRKKKSDLEFEALKTPDLDVPKDNIASDSLLTTNMASESTVRDSLPSLDLASATSGDKIVTAQ-----------------------ENGKAPDVQTVAGEVMGPQ--------------------------------RPRSNSGRELTDEEILASVMIKNLDTGEEIPLS-LAEEKLPTGINPLTPLTLHIMRRTKEYVSNDATQSDD-----EEKLQSQQTDT------DGGRLKQKTTQLKKFLGKSVKRAKHLAEEYGERAINKVKSVRDEVFHTDQDDPSSSDDEGMPYTRPVKFKAAHGFKGPYDFDQIKVVQDLSGEHMG---AVWTMKFSHCGRLLASAGQDNIVRIWALKNAFDYFNNMRMKYNTEGRVSPSPSQESLSSSKSDTDMGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWSKNYFLLSSSMDKTVRLWHISRRECLCCFQHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSHDFTYLVSGSEDKYVYIWSTYHDLSKFTSVRRDRNDFWEGIKAHNAVVTSAIFAPNPSLMLSLDVQSEKLEGIDKYEDAEVLDNTSTGIVKTDNTEVLLSADFTGAQCFYVKNSFLYP----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NVE8-1", "uniprot_id": "WDR44_MOUSE", "id": "Q6NVE8-1", "name": "WD repeat-containing protein 44", "aln": "---MASESDTEEFYDAPEDVHLGTGYPVG---------------SPGKVGLLSFKEAENTANQAGN---ESPVQELRQDVSKKIIESIIE--------------ESQKVLQLEDD-------SLDSKGKG----LSDEATAGPSVAGTEFSNIPGLLAIEHE------------LQQDSEKAESQNVAEESE--LETQKCFPSDETCEKSEKTVDETDN--------LTEVSSGEQLDASGLEAETLNKEALEVKEG-DVLDP----ASLDTLSTTDFAAVEEVAPAKPPR----------------HLTPEPD--------------------------------------------IVASTKKPVPARP--PPPTNFPPPRPPPPSRPAPPPRKKKSELEFEALKTPDLDVPKENITSDSLLTTNMASENTVRDSLPSLDLASATSGDKIVTAQ-----------------------ENGKAPDVQTVAGEVMGPQ--------------------------------RPRSNSGRELTDEEILASVMIKNLDTGEEIPLS-LAEEKLPTGIN---PLTLHIMRRTKEYVSNDATQSDD-----EEKLQSQQTDT------DGGRLKQKTTQLKKFLGKSVKRAKHLAEEYGERAINKVKSVRDEVFHTDQDDPSSSDDEGMPYTRPVKFKAAHGFKGPYDFDQIKVVQDLSGEHMG---AVWTMKFSHCGRLLASAGQDNIVRIWALKNAFDYFNNMRMKYNTEGRVSPSPSQESLSSSKSDTDMGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWSKNYFLLSSSMDKTVRLWHISRRECLCCFQHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSHDFTYLVSGSEDKYVYIWSTYHDLSKFTSVRRDRNDFWEGIKAHNAVVTSAIFAPNPSLMLSLDVQSEKLEGIDKYEDAEVLDSTSTGIVKTDNTEVLLSADFTGAIKVFINKRKTVS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JSH3-1", "uniprot_id": "WDR44_HUMAN", "id": "Q5JSH3-1", "name": "WD repeat-containing protein 44", "aln": "---MASESDTEEFYDAPEDVHLGGGYPVG---------------SPGKVGLSTFKETENTAYKVGN---ESPVQELKQDVSKKIIESIIE--------------ESQKVLQLEDD-------SLDSKGKE----LSDQATASPIVARTDLSNIPGLLAIDQV------------LPEESQKAESQNTFEETE--LELKKCFPSDETCEKP---VDETTK--------LTQTSSTEQLNVLETETEVLNKEAVEVKGGGDVLEP----VSSDSLSTKDFAAVEEVAPAKPPR----------------HLTPEPD--------------------------------------------IVASTKKPVPARP--PPPTNFPPPRPPPPSRPAPPPRKRKSELEFETLKTPDIDVPKENITSDSLLTASMASESTVKDSQPSLDLASATSGDKIVTAQ-----------------------ENGKAPDGQTVAGEVMGPQ--------------------------------RPRSNSGRELTDEEILASVMIKNLDTGEEIPLS-LAEEKLPTGIN---PLTLHIMRRTKEYVSNDAAQSDD-----EEKLQSQPTDT------DGGRLKQKTTQLKKFLGKSVKRAKHLAEEYGERAINKVKSVRDEVFHTDQDDPSSSDDEGMPYTRPVKFKAAHGFKGPYDFDQIKVVQDLSGEHMG---AVWTMKFSHCGRLLASAGQDNVVRIWALKNAFDYFNNMRMKYNTEGRVSPSPSQESLSSSKSDTDTGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWSKNYFLLSSSMDKTVRLWHISRRECLCCFQHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSHDFTYLVSGSEDKYVYIWSTYHDLSKFTSVRRDRNDFWEGIKAHNAVVTSAIFAPNPSLMLSLDVQSEKSEGNEKSEDAEVLDATPSGIMKTDNTEVLLSADFTGAIKVFVNKRKNVS----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IMK1-1", "uniprot_id": "Q8IMK1_DROME", "id": "Q8IMK1-1", "name": "WD repeat-containing protein 44", "aln": "MSKLETDSDSSEEFFDAEDTTPNRHSTLCRKLPPEVAQEFIFPEPAVRVNAAASSDSDATPIGAGTPATRSPTNSLGARLKPQDAGVFVEPKPVIGPLGRQRFHELRQCMQNDEDDNPGNTLTPDSQNSSTDGIFTNRSTHPFKVIETDAMSIQSMTSLGRVGRILAGSIDPSAISIDRESLASLNAQQQKQQAQQQQQAQPTSSTSSNTPPSVGNTSSGMSTPRVSPKHQQSGKEVAATTTGIPSAASSAQSSGVGSMVLQEPDVIASTKLAQSKTTDSITSSGPVAPPRRKKKSRNCSISSSDQYSLPPADNEDTDSDTRSVKSVQGLQQKLRDDFVMEFESSLNNATSSASNITLTCSSTNTVVSASASTSAASSSLPSTIAIHMRPMVASVTIAGPKLTQSLGSSSTSVHSKPSPSNSAKSNSAPARVSSIDPNQGLNLFKAIQGGYVVKPRDEASNKAQGPSQDEIERIEKMLMESANRPKLAGTGSNSLGSSTRYPGFYRGVNDKERRKSAGDEDVLKQMNIYVRTRTSSGKQLTDFEILEQVPVKNLDTGENMPLSEMRSPPVPEGWN---PLSLHILKLTSHLEVIQKESDEESVIGIPPSIEGQQPDEEELETEDGSRLKKKTARIKRFFGSTMR-----------KTVDKAKSIASEVSHARHKEDVADIVDAMNPEQNIKIKASSSNKGPYEFTKLQHVQDLSGEDTS---AVWCMKFSSCGRLLATAGQDKVLRIWVLKDAYPFFQDMRNKYNADQKSSPTPSQESLVSQHSAEEAIAMATAAEKCTG---PFMPKPFCTYNGHTSDLLDVSWSKNYFILSSSMDKTVRLWHISRKECLCCFQHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGQFAVVGSYDGRCIFYNTDQLKYHTQIHVRSTRGKNRIGRKISGIEPMPGEDKILVTSNDSRVRLYDLRDLNLSCKYKGYLNVSSQIKGSFSHDGKYIIAGSENQCIYIWKTNHDYSKLSSVRRDRSDFWEGIKAHNATVTCAIFAPHPEAIIKPEPDEISNEKLAHNQPDPLVEQHKKGCG-----YVLVSADFNGAIKVFINKTKPKHSSLPYTAIAD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03177-1", "uniprot_id": "YMZ2_YEAST", "id": "Q03177-1", "name": "WD repeat-containing protein YMR102C", "aln": "---MTNMAEDKTSISKVHSEFSNSSNTTG-----------------SEEESRSHQESFDGESSSGE---SKSKSKLNLEYSADIEPLKFR---------------MTKTNNTNDK--------LKYSNNG-------NATDSFMRLKEHLQRGNTLNSNLRVN-----------------EFYPFNSIDTEQ--FENYLREPKYIKMLKRRKNLKQFRR--------LFLAQELMAYEGETVTSTSKSSEPTSKAIWSTKFSR----------DGKFMATGSKDGKIRIWK-------------------------------------------------------------------VIGSPVERAELDS--SAESNKEARAKSMRIKQQVSSLNNPKEKQFLDSATEKYEEKEKLLNLYAPVFHPTPLRLYKEHVQDVLDINWSKN-NFILSAS-------------------------------MDKTVKLWHPD----------------------------------RKNSLKTFIHPDFVTCVEFHPTDDRFFISGCLDHKCRLWSILD----DEVSFEYDCQDLITSVTLSPEEG----KYTIIGTFNGY------VHILMTRGLTPVSSFHVADRQTQE-------QNAHVMVTETDSKIRHGPRVTGLQAFRSQLDNSFRLVVTSNDSRIRIFDLEQRKLLEVLKGFHSGSSQHKAQLSIWHGQPIVVNSSDDHWVYGWRLK------SSDRENDQDEPKRKPKGLARSGSLRSIFSKSMSRSSSQNNEEKPHHHLKLTNLLPLPHHSNDHYIKNTDYISFHAHNAPVTCVSIAPPETSKTLSLSNDVICELSLEFFQTSDSFDVLSRSNDDGIMSDVESS--LGYNSKPGSISNASATSAIPDVVDAIG------TILISTDNVG--TIRVFRADMPSVIRKRVLLKLEEYNREVRRRFNSSDS------LHSLSRSFNSRAKSNLAGQPAAAYTNTGKGYATGRGYSNICPKSS-TSLKTLGSNAQPR----TPRESMSSIFSNAHGPTTPTSAMNLPIRCNVCNGSRFEAFSGANDQQD---------RNYYCVDCGTVVNNFR-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . : .:: * .. ..* . . .. : : ::. . ... .:* . : : : . . * : : : *. . : : .. ... . .. . . : . . : .*. . . .. :. . . : .. . : . . .. : . . . *:: : . . ::.. : .. *..* : : . ::: * .: * :. . . : : : : .. . :: .: . . :.: : :. * : .: ... .:: * : . : : ..: . ::: : : :: *.* . . :.: ::..:.:*: : * ** .. * : : : : .*. .* . : : :. : : *: * . . * .: . * : . : *. :.: :: *. .* : : . :.. : :: .. :*. *. . :*:. : *: *: .*::: * .*: * : :* * : ..*.** *:.*. * : :. * :.* .:::: . :* . : .: . ..: * : * :: .: .: * .. * :. : : ..* . : ", "identical_positions": 54, "similar_positions": 268, "identity": "4.77%" }, { "cls_id": "homologset.agr.SGD:S000004710", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R4U9-1", "uniprot_id": "SGK2_RAT", "id": "Q8R4U9-1", "name": "Serine/threonine-protein kinase Sgk2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MASS----------------------------------------PVGV----PSP------------------------------------------------------------------------------QPSRANGNINLG----------------------------------------PSANPNARPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKNKEQSHIMAERNVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQREHRFLEPRARFYTAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKECVEPEETTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFFNTDVAQMYENILHQPLQIPGGRTVAACDLLQGLLHKDQRQRLGSKEDFLDIKNHMFFSPINWDDLYHKRLTPPFNPNVEGPADLKHFDPEFTQEAVSKSIG---CTPDT---MSSSSGASSAFLGFSYAQDDDDILDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZS5-1", "uniprot_id": "SGK2_MOUSE", "id": "Q9QZS5-1", "name": "Serine/threonine-protein kinase Sgk2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MASS----------------------------------------PVGV----PSP------------------------------------------------------------------------------QPSRANGNINLG----------------------------------------PSANPNARPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKNKEQNHIMAERNVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYTAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKECVEPEETTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFFNTDVAQMYENILHQPLQIPGGRTVAACDLLQGLLHKDQRQRLGSKEDFLDIKNHMFFSPINWDDLYHKRLTPPFNPNVEGPADLKHFDPEFTQEAVSKSIG---CTPDT---VASSSGASSAFLGFSYAQDDDDILDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HBY8-2", "uniprot_id": "SGK2_HUMAN", "id": "Q9HBY8-2", "name": "Serine/threonine-protein kinase Sgk2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MNSS----------------------------------------PAGT----PSP------------------------------------------------------------------------------QPSRANGNINLG----------------------------------------PSANPNAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQRQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEAVSKSIG---CTPDT---VASSSGASSAFLGFSYAPEDDDILDC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9ERE3-1", "uniprot_id": "SGK3_MOUSE", "id": "Q9ERE3-1", "name": "Serine/threonine-protein kinase Sgk3", "aln": "------------------------------MQRDCIMDYKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNSLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDS----------------------------------------PRHQ----SDPSE--------------------------------------------------------------------DEDERSTSKPHSTSRNINLG----------------------------------------PTGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLNLRPGVSLTAWSILEELLEKNRQNRLGAKEDFLEIQNHPFFESLSWTDLVQKKIPPPFNPNVAGPDDIRNFDAVFTEETVPYSVC---VSSDYSIVNASVLEADDAFVGFSYAPPSEDLFL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8R4V0-1", "uniprot_id": "SGK3_RAT", "id": "Q8R4V0-1", "name": "Serine/threonine-protein kinase Sgk3", "aln": "------------------------------MQRDCTMDYKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNSLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDS----------------------------------------PRHQ----SDPSE--------------------------------------------------------------------DEDERSTPKPHSTSRNINLG----------------------------------------PTGNPHAKPSDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDRTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLNLRPGVSLTAWSILEELLEKNRQNRLGAKEDFLEIQNHPFFESLSWTDLVQKKIPPPFNPNVAGPDDIRNFDAVFTEETVPYSVC---VSSDYSIVNASVLEADDAFVGFSYAPPSEDLFL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96BR1-1", "uniprot_id": "SGK3_HUMAN", "id": "Q96BR1-1", "name": "Serine/threonine-protein kinase Sgk3", "aln": "------------------------------MQRDHTMDYKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDS----------------------------------------PKHQ----SDPSE--------------------------------------------------------------------DEDERSSQKLHSTSQNINLG----------------------------------------PSGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVC---VSSDYSIVNASVLEADDAFVGFSYAPPSEDLFL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WVC6-1", "uniprot_id": "SGK1_MOUSE", "id": "Q9WVC6-1", "name": "Serine/threonine-protein kinase Sgk1", "aln": "---------------------------------------------MTVKAEAARST--LTYSRMRGMVAILIA------------------------------------------FMKQRRMGLNDFIQKIASNTYACKHAEVQSILKMSH----------------------------------------PQEPELMNANPS-----------------------------------------------------------------------------PPPSPSQQINLG----------------------------------------PSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSSIG---RSPDSILVTASVKEAAEAFLGFSYAPPVDSFL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06226-1", "uniprot_id": "SGK1_RAT", "id": "Q06226-1", "name": "Serine/threonine-protein kinase Sgk1", "aln": "---------------------------------------------MTVKTEAARST--LTYSRMRGMVAILIA------------------------------------------FMKQRRMGLNDFIQKLANNSYACKHPEVQSYLKISQ----------------------------------------PQEPELMNANPS-----------------------------------------------------------------------------PPPSPSQQINLG----------------------------------------PSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEAFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLK-NITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSSIG---RSPDSILVTASVKEAAEAFLGFSYAPPMDSFL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00141-1", "uniprot_id": "SGK1_HUMAN", "id": "O00141-1", "name": "Serine/threonine-protein kinase Sgk1", "aln": "---------------------------------------------MTVKTEAAKGT--LTYSRMRGMVAILIA------------------------------------------FMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQ----------------------------------------PQEPELMNANPS-----------------------------------------------------------------------------PPPSPSQQINLG----------------------------------------PSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIG---KSPDSVLVTASVKEAAEAFLGFSYAPPTDSFL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZTW4-1", "uniprot_id": "SGK1_DANRE", "id": "Q7ZTW4-1", "name": "Serine/threonine-protein kinase Sgk1", "aln": "---------------------------------------------MTIQTETSVSAPDLTYSKTRGLVANLSA------------------------------------------FMKQRKMGLNDFIQKLSANSYACKHPEVQSILNLTP----------------------------------------PQDVELMNSNPS-----------------------------------------------------------------------------PPPSPSQQINLG----------------------------------------PSSNPTAKPSDFDFLKVIGKGSFGKVLLARHRSDEKFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHYSFQTTDKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNISNAARHLLEGLLQKDRTKRLGFTDDFTEIKNHMFFSPINWDDLNAKKLTPPFNPNVTGPNDLRHFDPEFTDEPVPNSIG---CSPDSALVTSSITEATEAFLGFSYAPAMDSYL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AQL0-1", "uniprot_id": "A0A8M3AQL0_DANRE", "id": "A0A8M3AQL0-1", "name": "non-specific serine/threonine protein kinase", "aln": "--------------------------------------------------MVKKAKSPVTYAKMKGIVSYFTA------------------------------------------LIKDKKL----------RSSHPIYHHFYHSRMDFLR----------------------------------------PEGS---LSDDD-----------------------------------------------------------------------------RATAVCYSNPVR----------------------------------------EEPQSQVSAGDFDYLKVIGTGSFGKVFLATHRENGKYYAVKVLQKHIILTRKEERNVMCEHRVLLKTLNHPFLVKLHFSFQTKERLYLVLDYACGGELFYHLQREGVFGEARARFYAAEMACALGYLHSLKIVYRDLKPENILLDSAGHVVLTDFGLCKEGMSGRGTTRTFCGTPEYLAPEVLLQEEYDRTVDWWGLGAVLHEMLYGLPPFYNADRLEMLRNIIYQPLALKAGVSSAARDLLKRLLNRDRAKRLGAKRDLIELQSHAFFSPIQWDELVAKKIQPPYVPVLSGPGDLTNIDPRFTELPVPHSLG---ACEDHGANFPGFTFINENILSLTRGH--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18961-1", "uniprot_id": "YPK2_YEAST", "id": "P18961-1", "name": "Serine/threonine-protein kinase YPK2/YKR2", "aln": "MHSWRISKFKLGRSKEDDGSSEDENEKSWGNGLFHFHHGEKHHDGSPKNHNHEHEHHIRKINTNETLPSSLSSPKLRNDASFKNPSGIGNDNSKASERKASQSSTETQGPSSESGLMTVKVYSGKDFTLPFPITSNSTILQKLLSSGILTSSSNDASEVAAIMRQLPRYKRVDQDSAGEGLIDRAFATKFIPSSILLPGSTNSSPLLYFTIEFDNSITTISPDMGTMEQPVFNKISTFDVTRKLRFLKIDVFARIPSLLLPSKNWQQEIGEQDEVLKEILKKINTNQDIHLDSFHLPLNLKIDSAAQIRLYNHHWISLERGYGKLNITVDYKPSKNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLAR-VDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDLLIGLLSRDPSRRLGVN-GTDEIRNHPFFKDISWKKLLLKGYIPPYKPIVKSEIDTANFDQEFTKEKPIDSVVDEYLSASIQKQFGGWTYIGDEQLGDSPSQGRSIS---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . : : **. *****.*.:***: . :: **:*.*:* ::.. * : :.*: ** : : **:* *::***: ::**:** : *****:***:* * *:*** **: .*:. **.:.::************ **: * ****** : .* ************:: : * .:**** ** :*:**: ****:: : * :*: :** : . :* :* ** :: .*** . . :::.* **. :.* .* * **: * : . * ::* **. *: . . . :. : . ", "identical_positions": 124, "similar_positions": 93, "identity": "18.18%" }, { "cls_id": "homologset.agr.SGD:S000004711", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D0F9-1", "uniprot_id": "PGM1_MOUSE", "id": "Q9D0F9-1", "name": "Phosphoglucomutase-1", "aln": "----MVKIVTVKTQAYPDQKP-GTSGLRKRVKVFQSNANYAENFIQSIVSTVEPALRQEATLVVGGDGRFYMTEAIQLIVRIAAANGIGRLVIGQNGILSTPAVSCIIR--KIKAIGGIILTASHNPGGPNGDFGIKFNISNGGPAPEAITDKIFQISKTIEEYAICPDL-KVDLGVLGKQQFDLENKFKPFTVEIVDSVEAYATMLRNIFDFNALKELLSGPNR---LKIRIDAMHGVVGPYVKKILCEELGAPANSAVN-CVPLEDFGGHHPDPNLTYAADLVETMKSGEHDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVANATKIALYETPTGWKFFGNLMDASKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILATR-------KQSVEDILKDHWQKFGRNFFTRYDYEEVEAEGANKMMKDLEALMLDRSFVGKQFSANDKVYTVEKADNFEYSDPVDGSISKNQGLRLIFADGSRIIFRLSGT-GSAGATIRLYIDSYEKDVAKINQDPQVMLAPLISIALKVSQLQERTGRTAPTVIT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P38652-1", "uniprot_id": "PGM1_RAT", "id": "P38652-1", "name": "Phosphoglucomutase-1", "aln": "----MVKIVTVKTQAYPDQKP-GTSGLRKRVKVFQGNANYAENFIQSIVSTVEPALRQEATLVVGGDGRFYMTEAIQLIVRIAAANGIGRLVIGQNGILSTPAVSCIIR--KIKAIGGIILTASHNPGGPNGDFGIKFNISNGGPAPEAITDKIFQISKTIEEYAICPDL-KVDLGVLGKQQFDLENKFKPFTVEIVDSVEAYATMLRNIFDFNALKELLSGPNR---LKIRIDAMHGVVGPYVKKILCEELGAPANSAVN-CVPLEDFGGHHPDPNLTYAADLVETMKSGEHDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVANATKIASYETPTGWKFFGNLMDASKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILATR-------KQRVEDILKDHWQKFGRNFFTRYDYEEVEAEGANKMMKDLEALMLDRSFVGKQFSANDKVYTVEKADNFEYSDPVDGSISKNQGLRLIFADGSRIIFRLSGT-GSAGATIRLYIDSYEKDAAKINQDPQVMLAPLISIALKVSQLQERTGRTAPTVIT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36871-1", "uniprot_id": "PGM1_HUMAN", "id": "P36871-1", "name": "Phosphoglucomutase-1", "aln": "----MVKIVTVKTQAYQDQKP-GTSGLRKRVKVFQSSANYAENFIQSIISTVEPAQRQEATLVVGGDGRFYMKEAIQLIARIAAANGIGRLVIGQNGILSTPAVSCIIR--KIKAIGGIILTASHNPGGPNGDFGIKFNISNGGPAPEAITDKIFQISKTIEEYAVCPDL-KVDLGVLGKQQFDLENKFKPFTVEIVDSVEAYATMLRSIFDFSALKELLSGPNR---LKIRIDAMHGVVGPYVKKILCEELGAPANSAVN-CVPLEDFGGHHPDPNLTYAADLVETMKSGEHDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVASATKIALYETPTGWKFFGNLMDASKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILATR-------KQSVEDILKDHWQKYGRNFFTRYDYEEVEAEGANKMMKDLEALMFDRSFVGKQFSANDKVYTVEKADNFEYSDPVDGSISRNQGLRLIFTDGSRIVFRLSGT-GSAGATIRLYIDSYEKDVAKINQDPQVMLAPLISIALKVSQLQERTGRTAPTVIT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BZF8-1", "uniprot_id": "PGM5_MOUSE", "id": "Q8BZF8-1", "name": "Phosphoglucomutase-like protein 5", "aln": "MEGSPIPVLTVPTAPYEDQRPTGGGGLRRPTGLFEGQRNYLPNFIQSVLSSIDLRDRQGCTMVVGSDGRYFSRTATEIVVQMAAANGIGRLIIGQNGILSTPAVSCIIR--KIKAAGGIILTASHCPGGPGGEFGVKFNVANGGPAPDVVSDKIYQISKTIEEYAICPDL-RIDLSRLGRQEFDLENKFKPFRVEIVDPVDIYLNLLRNIFDFNAIKSLLTGPSQ---LKIRVDAMHGVMGPYVRKVLCDELGAPANSAIN-CVPLEDFGGQHPDPNLTYATTLLEAMKGGEYGFGAAFDADGDRYMILGQNGFFVSPSDSLAIIAANLSCIPYFRQMGVRGFGRSMPTSTALDRVAKSMKVPVYETPAGWRFFSNLMDSGRCSLCGEESFGTGSDHLREKDGLWAVLVWLSIIAAR-------KQSVEEIVRDHWAKYGRHYYCRFDYEGLEPKATYYIMRDLEALVTDKSFIGQQFAVGSHIYSIAKTDSFEYVDPVDGTVTKKQGLRIIFSDASRLIFRLSSS-SGVRATIRLYAESYERDPSGHDQEPQAVLSPLIAIALKISQIHERTGRRGPTVIT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZVR9-1", "uniprot_id": "PGM5_RAT", "id": "D3ZVR9-1", "name": "Phosphoglucomutase-like protein 5", "aln": "MEGSPIPVLTVPTAPYEDQRPTGGGGLRRPTGLFEGQRNYLPNFIQSVLSSIDLRDRQGCTMVVGSDGRYFSRTATEIVVQMAAANGIGRLIIGQNGILSTPAVSCIIR--KIKAAGGIILTASHCPGGPGGEFGVKFNVANGGPAPDVVSDKIYQISKTIEEYTICPDL-RIDLSRLGRQEFDLENKFKPFRVEIVDPVDIYLNLLRTIFDFNAIKSLLTGPSQ---LKIRVDAMHGVMGPYVRKVLCDELGAPANSAIN-CVPLEDFGGQHPDPNLTYATTLLEAMKGGEYGFGAAFDADGDRYMILGQNGFFVSPSDSLAIIAANLSCIPYFRQMGVRGFGRSMPTSMALDRVAKSMKVPVYETPAGWRFFSNLMDSGRCSLCGEESFGTGSDHLREKDGLWAVLVWLSIIAAR-------KQSVEEIVRDHWAKYGRHYYCRVLYEAKSPKATYYIMRDLEALVTDKSFIGQQFAVGSHIYSIAKTDSFEYVDPVDGTVTKKQGLRIIFSDASRLIFRLSSS-SGVRATIRLYAESYERDPSGHDQEPQAVLSPLIAIALKISQIHERTGRRGPTVIT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15124-1", "uniprot_id": "PGM5_HUMAN", "id": "Q15124-1", "name": "Phosphoglucomutase-like protein 5", "aln": "MEGSPIPVLTVPTAPYEDQRPAGGGGLRRPTGLFEGQRNYLPNFIQSVLSSIDLRDRQGCTMVVGSDGRYFSRTAIEIVVQMAAANGIGRLIIGQNGILSTPAVSCIIR--KIKAAGGIILTASHCPGGPGGEFGVKFNVANGGPAPDVVSDKIYQISKTIEEYAICPDL-RIDLSRLGRQEFDLENKFKPFRVEIVDPVDIYLNLLRTIFDFHAIKGLLTGPSQ---LKIRIDAMHGVMGPYVRKVLCDELGAPANSAIN-CVPLEDFGGQHPDPNLTYATTLLEAMKGGEYGFGAAFDADGDRYMILGQNGFFVSPSDSLAIIAANLSCIPYFRQMGVRGFGRSMPTSMALDRVAKSMKVPVYETPAGWRFFSNLMDSGRCNLCGEESFGTGSDHLREKDGLWAVLVWLSIIAAR-------KQSVEEIVRDHWAKFGRHYYCRFDYEGLDPKTTYYIMRDLEALVTDKSFIGQQFAVGSHVYSVAKTDSFEYVDPVDGTVTKKQGLRIIFSDASRLIFRLSSS-SGVRATLRLYAESYERDPSGHDQEPQAVLSPLIAIALKISQIHERTGRRGPTVIT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0R0B3-1", "uniprot_id": "PGM5_DANRE", "id": "B0R0B3-1", "name": "Phosphoglucomutase-like protein 5", "aln": "METNPIPILTIQTTPFDDQRP-GTNGLRKKTAVFESNNNYLQNYIQSVLSSIDLRDRQGCTMVVGSDGRYFSRAATEVIVQMAAANGIGRLVIGHNGILSTPAVSCIIR--KIKAIGGIILTASHSPGGPGGDFGIKFNVANGGPSPDTVIERIHQVSRTLEEYAICPDL-HIDLSRLGRQDFDLENKFKPFRVEIVDSVEIYFNLLRGIFDFSGIKSLLTGPNQ---LKIRIDAMNGVMGPYVRRILCDELGAPANSAVN-CVPLEDFGGQHPNPNPAFAGPLVDSMKGGEFGFGAAFDADGDRYMIMGENGFFVSPSDSLAVMAANLSCIPYFSQRGIRGFARSMPTSTAIDRVAKAMKVALYETPTGWRFFGNLLDSGRCSFCGEESFGTGSDHIRDKDGLWSVLVWLSIMAVR-------KQGVEEIVRDHWAKLGRNYFCRFDYEGVDGKAAFYLMRDLEAVITDKAFTTQKFSVGNTVYSVEKADNFEYIDPVDGSVSRKQGLRIIFTDSSRIIFRLSGSGSGTGATVRIYAESYERDPERHNRETQVVLGPLIAIALKISNIHERTGRRGPNIIT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUY9-1", "uniprot_id": "PGM_DROME", "id": "Q9VUY9-1", "name": "Phosphoglucomutase 1", "aln": "---MSLTVEIVATKPYEGQKP-GTSGLRKKVKVFT-QPNYTENFVQAILEANG-AALAGSTLVVGGDGRFYCKEAAELIVRLSAANGVSKLLVGQNGILSTPAVSSLIR--HNKALGGIVLTASHNPGGPENDFGIKFNCENGGPAPDAFTNHIYKITTEIKEYKLVRNL-QIDISKVGVTSFDIAG--KPFTVEVIDSVANYVRHMEEIFDFAKLKDFVSGKATGKPLKMRIDAMNGVTGSYVREIFLNRLGATESSVVH-TTPLPDFGGLHPDPNLTYAKDLVDTVAQGDYDIGAAFDGDGDRNMIIGSKAFFVTPSDSLAVIAHYLEAIPYFQKNGVQGFARSMPTASAVDLVGRKLGKEVFEVPTGWKYFGNLMDAGRLCLCGEESFGTGSNHIREKDGIWAVLAWISVMQHT-------GKGIEDILKQHWSVYGRNYFTRYDYEECASDPCNEMVATMEKTITAPEFVGKSYSSGGKTYKVKEADNFSYTDPVDKSVATKQGLRIVFEDGSRIVVRLSGT-GSSGATVRLYIDSYEKE--NVLGQASVMLKPLIDIALEISQLPKFTGRNAPTVIT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P37012-1", "uniprot_id": "PGM2_YEAST", "id": "P37012-1", "name": "Phosphoglucomutase 2", "aln": "---MSFQIETVPTKPYEDQKP-GTSGLRKKTKVFKDEPNYTENFIQSIMEAIP-EGSKGATLVVGGDGRYYNDVILHKIAAIGAANGIKKLVIGQHGLLSTPAASHIMRTYEEKCTGGIILTASHNPGGPENDMGIKYNLSNGGPAPESVTNAIWEISKKLTSYKIIKDFPELDLGTIGKN-----KKYGPLLVDIIDITKDYVNFLKEIFDFDLIKKFIDNQRSTKNWKLLFDSMNGVTGPYGKAIFVDEFGLPADEVLQNWHPSPDFGGMHPDPNLTYASSLVKRVDREKIEFGAASDGDGDRNMIYGYGPSFVSPGDSVAIIAEYAAEIPYFAKQGIYGLARSFPTSGAIDRVAKAHGLNCYEVPTGWKFFCALFDAKKLSICGEESFGTGSNHVREKDGVWAIMAWLNILAIYNKHHPENEASIKTIQNEFWAKYGRTFFTRYDFEKVETEKANKIVDQLRAYVTKSGVVNSAFP-ADESLKVTDCGDFSYTD-LDGSVSDHQGLYVKLSNGARFVLRLSGT-GSSGATIRLYIEKYCDDKSQYQKTAEEYLKPIINSVIKFLNFKQVLGTEEPTVRT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : * .: .*:* * .***: . :* . ** *::*:::.: .*:***.***:: . :. :.****: :*::*::*:*****.* ::* . *. ***:***** **** .::*:*:* ****:*: . : * ::: : .* : :: .:*:. :* *: *:::* . * :. **** :* :: . *: .*:*:** *.* : :: :.:* . ...:: * **** **:** ::* *:. : . :*** *.**** ** * **.*.**:*::* **** : *: *:.**:**: *:* *. :*.*:**::* *:*: : :**********:*:*:***:*:::.*:.:: :: * .:.* ** :: * :* . :: :. : . . :. . .: . ..*.* * :* ::: :*** : : :.:*::.***.: .. **:*:* :.* : .. * *:* .::. :: : * *.: *", "identical_positions": 169, "similar_positions": 194, "identity": "29.04%" }, { "cls_id": "homologset.agr.SGD:S000004712", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V817-1", "uniprot_id": "G3V817_RAT", "id": "G3V817-1", "name": "DNA repair protein Ku80", "aln": "MAWSGNKAAVVLCMDVGVAMGNSFPGEESPLEQAKKVMTMFVQRQVFSESKDEIALVLYGTESTDNALAGKDQYQNITVHRHLMLPDFD-LLEDIGNKIQPSSQQA--DFLDALIVCMDLIQRETIGKKFGKKHIEVFTDLSSPFSQDQLDIIICNLKKSSISLQFFLPFPIDKNGEPGETEDHDSSFDHCAPSFPQKGLTEQQKEGIHMVTRVMLSLEGKDGLDEIYSFSESLQQLCIFKKIERRSLPWPCQLTIGPNLSIRIVAYKSIVQEKFKKSWVVVDARTLKKEDIQKETVYCLNDDDETEVSKEDTIQGFRYGSDIIPFSKVDEEQMKYKSEGKCFSVLGFCKSSQVHRRFFMGHQVLKVFAAKDDEAAAVALSSLVHALDELNMVAIVRYAYDKRAN-PQVGVAFPFIKDA--YECLVYVQLPFMEDLRQYMFSSLKNNKKCTPTEAQLSAIDDLIDSMSLVKKNEEED-----IIEDLFPTSKIPNPEFQRLYQCLLHRALHL---QERLPPIQQHILNMLDPPTEMKAKCEIPLSKVKTLFPLTEVVKKKDQVTAQDVFQDNIEEGPAAKKYKTEKEEGHISISSLAEGNVTKVGSVNPVENFRVLVRQKIASFEEASLQLMSHIEQFLDTNETLYFMKSMDCIKALREEAIQFSEEQRFNSFLEGLREKVEIKQLNHFWEIVVQDGITLITKDESPGSSVTAEEATKFLTPKDKAKEDTTGL-EEGGDVDDLLDMI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P27641-1", "uniprot_id": "XRCC5_MOUSE", "id": "P27641-1", "name": "DNA repair protein Ku80", "aln": "MAWSGNKAAVVLCVDVGVAMGNSFPGEESPIEQAKKVMTMFVQRQVFSESKDEIALVLYGTDGTDNALAGKDQYQNITVCRHLMLPDFD-LLEDIGNKIQPSSQQA--DFLDALIVCMDLIQRETIGKKFGKKHIEVFTDLSSPFSQDQLDVIICNLKKSGISLQFFLPFPIDKNGEPGERGDLDSGLDHLKPSFPQKGLTEQQKEGIRMVTRVMLSLEGEDGLDEIYSFSESLRQLCVFKKIERRSMPWPCQLTIGPNLSIKIVAYKSIVQEKFKKSWVVVDARTLKKEDIQKETVYCLNDDDETEVSKEDTIQGYRYGSDIIPFSKVDEEQMKYKSEGKCFSVLGFCKSSQVHRRFFMGHQVLKVFAAKDDEAAAVALSSLVHALDELNMVAIVRYAYDKRSN-PQVGVAFPYIKDA--YECLVYVQLPFMEDLRQYMFSSLKNNKKCTPTEAQLSAIDDLIDSMSLVKKNEEED-----IVEDLFPTSKIPNPEFQRLYQCLLHRALHL---QERLPPIQQHILNMLDPPTEMKAKCESPLSKVKTLFPLTEVIKKKNQVTAQDVFQDNHEEGPAAKKYKTEKEEDHISISSLAEGNITKVGSVNPVENFRFLVRQKIASFEEASLQLISHIEQFLDTNETLYFMKSMDCIKAFREEAIQFSEEQRFNSFLEALREKVEIKQLNHFWEIVVQDGVTLITKDEGPGSSITAEEATKFLAPKDKAKEDTTGP-EEAGDVDDLLDMI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13010-1", "uniprot_id": "XRCC5_HUMAN", "id": "P13010-1", "name": "DNA repair protein Ku80", "aln": "MVRSGNKAAVVLCMDVGFTMSNSIPGIESPFEQAKKVITMFVQRQVFAENKDEIALVLFGTDGTDNPLSGGDQYQNITVHRHLMLPDFD-LLEDIESKIQPGSQQA--DFLDALIVSMDVIQHETIGKKFEKRHIEIFTDLSSRFSKSQLDIIIHSLKKCDISLQFFLPFSLGKEDGSGDRGDGPFRLGGHGPSFPLKGITEQQKEGLEIVKMVMISLEGEDGLDEIYSFSESLRKLCVFKKIERHSIHWPCRLTIGSNLSIRIAAYKSILQERVKKTWTVVDAKTLKKEDIQKETVYCLNDDDETEVLKEDIIQGFRYGSDIVPFSKVDEEQMKYKSEGKCFSVLGFCKSSQVQRRFFMGNQVLKVFAARDDEAAAVALSSLIHALDDLDMVAIVRYAYDKRAN-PQVGVAFPHIKHN--YECLVYVQLPFMEDLRQYMFSSLKNSKKYAPTEAQLNAVDALIDSMSLAKKDEKTD-----TLEDLFPTTKIPNPRFQRLFQCLLHRALHP---REPLPPIQQHIWNMLNPPAEVTTKSQIPLSKIKTLFPLIEAKKK-DQVTAQEIFQDNHEDGPTAKKLKTEQGGAHFSVSSLAEGSVTSVGSVNPAENFRVLVKQKKASFEEASNQLINHIEQFLDTNETPYFMKSIDCIRAFREEAIKFSEEQRFNNFLKALQEKVEIKQLNHFWEIVVQDGITLITKEEASGSSVTAEEAKKFLAPKDKPSGDTAAVFEEGGDVDDLLDMI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I7M8-1", "uniprot_id": "Q9I7M8_DROME", "id": "Q9I7M8-1", "name": "ATP-dependent DNA helicase II subunit 2", "aln": "--MASNKECLIIVLDVRTCAAEEVK------LKSAKCVAEILKDKIVCDRKDYVSFVLVGCDTDEIKTEDASHPNVLPFGEPRLCSWQL-LLEFFQFVNKTACEDG--EWLNGLQAALELQNVATTLRVARRRILLLFDFNDFPQDYEKFNEITDELLGENIELIVGTHNIAYIDNAITSQPQAIFNFSRKCGPDELN----NQKYALSLVPRCNATL---------CSFKEALH--TVFKVTNRRPWVWNAKLNIGSKISISLQG---IIAMKNQTPVKLVKVWAEKDEIVIRETRHYIKGTEITPLP-ENLITGYMLGGTPVPYDEAVLEPKEPHPPG--LHFFGFIKRNAVPDEYFCGESLYLLVHQKHNQSAAVKLDALVRALVSSDRAILCWKIYSTKFNRPQMVVLLPRLADDTHPATLYMLEVSYTSQHHFWDFPALR-TTKTECSEEQLNAIDQLIDSTDLECTLRDTQQPRPWAQNDLLPFDALPSIFEQNVMDILERKVIYDNDKEDKMLKDKNFADVFWRVPDPLEEKSKRAAAIVKKLFPLRYSRAWQEKLLAKEQAENGVAVKSEPAEKEIPLPSDGVGLIDPISDFRRVLASVHTISN----ATERDARFQALAADTRVVIITLLQR-RKQNIGQLGELITLYRQSCIDFNTFLEYDKFAEELKKIALAKNRSEFWQDVMVD--------KQLGPLVLGEPTLDDELALKAYYTIENWVESGANDMEDVEM--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04437-1", "uniprot_id": "KU80_YEAST", "id": "Q04437-1", "name": "ATP-dependent DNA helicase II subunit 2", "aln": "--MSSESTTFIVDVSPSMMKNNNVS------KSMAYLEYTLLNKSKKSRKTDWISCYLANCPVSENSQEIPNVFQIQSFLAPVTTTATIGFIKRLKQYCDQHSHDSSNEGLQSMIQCLLVVSLDIKQQFQARKILKQIVVFTDNLDDLDITDEEIDLLTEELSTRIILIDCG-KDTQEERKKSNWLKLVEAIPN--------SRIYNMNELLVEITSP---------------------ATSVVKPVRVFSGELRLGADILSTQTSNPSGSMQDENCLCIKVEAFP------ATKAVSGLNRKTAVEVEDSQKKERYVGVKSIIEYEIHNEGNKK-----------------NVSEDDQSGSSYIPVTISKDSVTKAYRYGADYVVLPS---VLVDQTVYESFPG----------------LDLRGFLNREALPRYFLTSESSFITADTRLGCQSDLMAFSALVDVMLENRKIAVAR----------YVSKKDSEVNMCALCPVLIEHSNINS--EKKFVKSLTLCRLPFAEDERVTDFPKLLDRTTTSGVPLKKETDGHQIDELMEQFVDSMDTDELP---EIPLGNYYQPIGEVTTDTTLPLPSLNKDQE-----ENKKDPLRIPTVFVYRQQQVLLEWIHQLMINDSREFEIPELPDSLKN-KISPYTHKKFDSTKLVEVLGIKKVDKLKLDS---------ELKTELEREKIPDLETLLKRGEQHSRGSPNNSNN--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:. .:: :. :.. . ::: . . .* :: * . : . : .. . ::: : . ..:. : *:.: .: : . : :: : : . .: .* :. . : . : .: : : : . : : .* :*..: . : *.. . :: :: . : .: : : :. : * * . : :.. : * .: .* . . : *.. . :: .:: . : :* *.. *:* . .. : * .: .. : : : .. .** : : :. . : : . . : *:: .: :: :. : :*: . : . : ..:. : : . ... : : . . : * . . . ..: ", "identical_positions": 22, "similar_positions": 177, "identity": "2.95%" }, { "cls_id": "homologset.agr.SGD:S000004715", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9Q634-1", "uniprot_id": "MYO1E_MOUSE", "id": "E9Q634-1", "name": "Unconventional myosin-Ie", "aln": "-----------------MGSKGAYRYHWQSHNVKHSGVDDMVLLS-KITESSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEVEMYQGAAQYENPPHIYALADSMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYVSRVSGGGPK--VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASPEQKQSLGIT-SMDYYYYLSLSGSYKVDDIDDKRDFQETLHAMNVIGIFSEEQTLVLQIVAGILHLGNISFKE-VGNYAAVESEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGG-KSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSIN-----KAMEK-DHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIESKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEHFN------------SWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLFPENLQADKK--GRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFQKFLQRYAILTKATWPV----WRGDEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKTWRKFVAR------------------KKYVQMREEASDLLLNKKERRRNSIN--RNFIGDYIGMEERPE----LQQFVGKREKIDFADT----VTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGVVKEVLKRRIEVERILSVSLSTMQDDIFILHEQEY---DSLLESVFKTEFLSLLAKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQFHQGFGDLAILKPSNKVLQVSIGPGLPKNSRPTRRNTVTSRGYPGGTKN-NYPMRAAPAPP-GCHQNGVIRNQFV--PPPHAFGNQRSNQKSLYTSMARPPLPRQQSTGSDRLSQTPESLDFLKVPDQGVAGVRRQTSSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDT-DELSFNANDIIDIIKEDPSGWWTGRLR--GKQGLFPNNYVTKI--------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63356-1", "uniprot_id": "MYO1E_RAT", "id": "Q63356-1", "name": "Unconventional myosin-Ie", "aln": "-----------------MGSKGAYRYHWQSHNVKHSGVDDMVLLS-KITESSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGAAQYENPPHIYALADSMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYVSRVSGGGPK--VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASPEQKQSLGIT-SMDYYYYLSLSGSYKVDDIDDKRDFQETLHAMNVIGIFSEEQTLVLQIVAGILHLGNINFKE-VGNYAAVESEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGG-KSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSIN-----KAMEK-DHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIESKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEHFN------------SWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLFPENLQADKK--GRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFQKFLQRYAILTKATWPV----WRGDEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKTWRKFVAR------------------KKYVQMREDASDLLLNKKERRRNSIN--RNFIGDYIGMEEHPE----LQQFVGKREKIDFADI----VTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEVERILSVSLSTMQDDIFILHEQEY---DSLLESVFKTEFLSLLTKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQFYQGFGDLAILKPSNKVLQVSIGPGLPKNARPTRRNTVSSRGYSGGTNN-NYPMRAAPAPP-GCHRNGLTRNQFV--HPPRASGNQRSNQKSLYTSMARPPLPRQQSTGSDRLSQTPESLDFLKVPDQGAAGVRRQTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDT-DELSFNANDVIDIIKEDPSGWWTGRLR--GKQGLFPNNYVTKI--------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12965-1", "uniprot_id": "MYO1E_HUMAN", "id": "Q12965-1", "name": "Unconventional myosin-Ie", "aln": "-----------------MGSKGVYQYHWQSHNVKHSGVDDMVLLS-KITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTK--VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGIT-SMDYYYYLSLSGSYKVDDIDDRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKE-VGNYAAVESEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGG-KSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSIN-----KAMEK-DHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEHFN------------SWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLFPENLQADKK--GRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPS----WQGEEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVAR------------------KKYVQMREEASDLLLNKKERRRNSIN--RNFIGDYIGMEEHPE----LQQFVGKREKIDFADT----VTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEIERILSVSLSTMQDDIFILHEQEY---DSLLESVFKTEFLSLLAKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQFHQGFGDLAVLKPSNKVLQVSIGPGLPKNSRPTRRNTTQNTGYSSGTQNANYPVRAAPPPP-GYHQNGVIRNQYV--PYPHAPGSQRSNQKSLYTSMARPPLPRQQSTSSDRVSQTPESLDFLKVPDQGAAGVRRQTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDT-DELSFNANDIIDIIKEDPSGWWTGRLR--GKQGLFPNNYVTKI--------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O00160-1", "uniprot_id": "MYO1F_HUMAN", "id": "O00160-1", "name": "Unconventional myosin-If", "aln": "-----------------MGSK--ERFHWQSHNVKQSGVDDMVLLP-QITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEK--VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLM-TPDYYYYLNQSDTYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCE-DGNYARVESVDLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGG-RSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAIN-----RAMQK-PQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTHEHFN------------SWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFLRMLFPEKLDGDKK--GRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPR----WRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAV------------------RKYEEMREEASNILLNKKERRRNSIN--RNFVGDYLGLEERPE----LRQFLGKRERVDFADS----VTKYDRRFKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQALRGVSLSTRQDDFFILQEDAA---DSFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRVKKEGWG---GGGTRSVTFSRGFGDLAVLKVGGRTLTVSVGDGLPKSSKPTRKGMAKGK----PRRSSQAPTRAAPAPPRGMDRNGVPPSARG-GPLPLEIMSGGGTHRPPRGPPSTSLG---ASRRPRARPPSEHNTEFLNVPDQGMAGMQRKRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDV-DELSFNVNEVIEILMEDPSGWWKGRLH--GQEGLFPGNYVEKI--------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A7X9-1", "uniprot_id": "D4A7X9_RAT", "id": "D4A7X9-1", "name": "", "aln": "-----------------MGSK--ERFHWQSHNVKQSGVDDMVLLP-QITEDAIVSNLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGDK--VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQQQNLGLM-TPDYYYYLNQSDTYKVEGTDDRSDFNETLNAMQVIGIPTSVQQLVLQLVAGILHLGNISFCE-EGNYARVESVDLLAFPAYLLGIDSGRLQEKLTSRKMDSKWGG-RSESIDVTLNVEQAAYTRDALAKGLYARLFDFLVEAIN-----RAMQK-PQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKLNPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTHEHFN------------SWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQSSDQAFLRMLFPEKLDVDKK--GRPSTAGSKIKKQANDLVSTLKKCTPHYIRCIKPNETKRPRDWEESRVKHQVEYLGLRENIRVRRAGFAYRRQFSKFLQRYAILTPETWPR----WRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEMRERKFDGFARTIQKAWRRHIAV------------------RKYEEMREEASNILLNKKERRRNSIN--RNFVGDYLGLEERPE----LRQFLAKRERVDFADS----VTKYDRRFKPIKRDLILTPKCVYVIGREKVKKGPEKGLVREVLKKKLEIQALRGVSLSTRQDDFFILQEEAA---DSFLESIFKTEFVSLLCKRFEEAARRPLPLTFSDMLQFRVKKEGWG---GGSTRNVTFSRGTGDLAVLKAGSRALTISIGDGLPKSTKPTRKGLAQGR----PRRSAQAPTRAAPGPPRGLNRNGVPPSSQV-RSLPMEITSGRSSQRPPRGPPSSTLG---ASRRPRARPPSEHNTEFLNVPDQGVAGMQRKRSIGQRPVPGVGRPKPQPRTHGPRCRALYQYIGQDV-DELSFNVNEVIEILMEDSSGWWKGRLH--GQEGLFPGNYVEKI--------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70248-1", "uniprot_id": "MYO1F_MOUSE", "id": "P70248-1", "name": "Unconventional myosin-If", "aln": "-----------------MGSK--ERFHWQSHNVKQSGVDDMVLLS-QITEDAIVRNLHKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGAVQYEEPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGDK--VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQQQNLGIM-SQDYYYYLNQSDTYKVEGTDDRSDFSETLSAMQVMGFRQACQQLVLQLVAGILHLGNISFCE-EGNYARVESVDSLAFPAYLLGIDSGRLQEKLTSRKMDSKWGG-RSESIDVTLNVEQAAYTRDALAKGLYARLFDFLVEAIN-----RAMQK-PQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTHEHFN------------SWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQSSDQDFLRMLFPEKLNIDKK--GRPSTAGSKIKKQANDLVSTLKKCTPHYIRCIKPNETKRPRDWEESRVKHQVEYLGLRENIRVRRAGFAYRRQFSKFLQRYAILTPETWPR----WRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEMRERKFDGFARTIQKAWRRHVAV------------------RKYEEMREEASNILLNKKERRRNSIN--RNFVGNYLGLEERPE----LRQFLAKRERVDFADS----VTKYDRRFKPIKRDLILTPKCVYVIGTEKVKRGPEKGLVREVLKKKLDIQALRGVSLSTRQDDFFILQEEAA---DTFLESIFKTEFVSLLCKRFEEAARRPLPLTFQDILQFRVKKKGWG---GGGTRNVTFSAGQVNLAVLKAGGKTLTISLGDGLPKNSKPTRKGLAQGK----PRRSAQAPTRAVPWASQGLNRNGATLFPRGEGPYTLEIYIWP--QEFPEASTAIHLQPQDASRRPRARPPSEHSTEFLNVPDQGVAGMQRKRSIGQRPVP-ASRPKPQPRTHGPRCRALYQYIGQDV-DELSFNVNEVIEILIEDSSGWWKGRLH--GQEGLFPGNYVEKI--------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04439-1", "uniprot_id": "MYO5_YEAST", "id": "Q04439-1", "name": "Myosin-5", "aln": "MAILKRGARKKVHQEPAKRSANIKKATFDSSKKKEVGVSDLTLLS-KISDEAINENLKKRFLNATIYTYIGHVLISVNPFRDLGIYTDAVMNEYKGKNRLEVPPHVFAIAESMYYNMKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASSTHTES-IGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNNQFEPCAGNITNYLLEKQRVVSQIKNERNFHIFYQFTKGASDAYRQTFGVQ-KPEQYVYTAAAGCISAETIDDLQDYQETLKAMRVIGLGQEEQDQIFRMLAAILWIGNVSFIENEEGNAQVRDTSVTDFVAYLLQIDSQLLIKSLVERIMETNHGMKRGSVYHVPLNIVQADAVRDALAKAIYNNLFDWIVSRVN-----KSLQAFPGAEKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKSEQETYEREKIQWTPIKYFDNKVVCDLIEARR-PPGIFAAMNDSVATAHADSNAADQAFAQRLNLFT-TNPHFD------------LRSNKFVIKHYAGDVTYDIDGITDKNKDQLQKDLVELIGTTTNTFLATIFPDTVDRESK--RRPPTAGDKIIKSANDLVETLSKAQPSYIRTIKPNETKSPNDYDDRQVLHQIKYLGLQENVRIRRAGFAYRQVFEKFVERFYLLSPHCSYAGDYTWQGDTLDAVKYILQDSSIPQQEYQLGVTSVFIKTPETLFALEHMRDRYWHNMAARIQRAWRRFLQRRIDAATKIQRTIRERKEGNKYEKLRDYGTKVLGGRKERRSMSLLGYRAFMGDYLSCNESKSKGAYIKRQVSIKEKVIFSIHGEALHTKFGRSAQRLKKTFLLTPTTLYIVGQTLVQN-----AMTYTQDYKIDVRNIQAVSLTNLQDDWVAIKLASSGQPDPLINTYFKTELITHLKR-----LNDKIQIKIGSAIEYQKKP---------GKLHSVKCQINESAPKYGDIYKSSTISVRRGNPPNSQVHKKPRKKSSISSGYHASSSQATRRPVSIAAAQHVPTAPASRHSKKPAPPPPGMQNKAATRRSVPNPASTLTASQSNARPSPPTAATRATPAATPAAAAMGSGRQANIPPPPPP----PPPSSKPKEPMFEAAYDFPGSGSPSELPLKKGDVIYITREEPSGWSLGKLLDGSKEGWVPTAYMKPHSGNNNIPTPPQNRDVPKPVLNSVQHDNTSANVIPAAAQASLGDGLANALAARANKMRLESDDEEANEDEEEDDW", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q23978-1", "uniprot_id": "MY31D_DROME", "id": "Q23978-1", "name": "Unconventional myosin ID", "aln": "-----------------------MAMQR------EAGVQDFVLLD-QVSMEKFMDNLRKRFQNGSIYTYIGEVCVSMNPYRQMNIYGPETIRKYKGRELFENAPHLFAIADSAYRVLKQRQQDTCILISGESGAGKTEASKIIMKYIAAVTNAQGQNEIERVKNVLIQSNAILETFGNAKTNRNDNSSRFGKYMDIEFDYKADPVGGIITNYLLEKSRVVQQQPGERNFHSFYQLLRGANDNELRQYELQKETGKYHYLNQ---GSMDILTEKSDYKGTCNAFKTLGFSTDEVQTIWRTIAAVLHLGNVEFQT-IEDELVISNKQHLKSTAKLLQVTETELSTALTKRVIAA-----GGNVMQKDHNATQAEYGKDALAKAIYDRLFTWIISRINRAILFRGSKTQARFNSVIGVLDIYGFEIFDSNSFEQFCINYCNEKLQQLFIELVLKQEQEEYQREGIEWTNIEYFNNKIICDLVEQPH--KGIIAIMDEACLSVGKV---TDDTLLGAMDKNLSKHPHYTSRQLKPTD-KELKHREDFRITHYAGDVIYNINGFIEKNKDTLYQDFKRLLHNSKDANLSEMWPEGAQDIKKTTKRPLTAGTLFQRSMADLVVTLLKKEPFYVRCIKPNDLKSSTVFDEERVEHQVRYLGLLENLRVRRAGFVHRQRYDKFLLRYKMISQYTWPNFR---AGSDRDGVRVLIEEKKFAQD-VKYGHTKIFIRSPRTLFALEHQRNEMIPHIVTLLQKRVRGWIVR------------------RNFKKMKAAITIVRAYK------------------------------------------------------AYKLRSYVQELANR--------------------LRKAKQMRDYGKSIQ-----------WPQPPLAGRKVEAKLHRMFDFWRANMILHKYPRSEWPQLRLQIIAATALAGRRPYWGQARRWVGDYLANSQENSGYEAYNGSIKNIRNHPADGETFQQVLFSSFVKKFN------HFNKQANRAFIVSDSTIHKLDGIKNKFK---DMKRTIKIRELTSISVSPGRDQLIVFHSSKNKDLVFSLESEYTPLKEDRIGEVVGIVCKKYHDLTGTELRVNVTTNISCRLDGKARIITVEAASNVEVPNFRPKEGNIIFEVPAAYCV----------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q23979-1", "uniprot_id": "MY61F_DROME", "id": "Q23979-1", "name": "Unconventional myosin IC", "aln": "----------------MASFNSQLKMETGLHERDRAGVQDFVLLENYQSEEAFIGNLKKRFQEDLIYTYIGQVLISVNPYKQLPIYTDDHVKAYRNKHFYEMPPHIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEASKKVLQFIAACS--GNQTTVEGVKDKLLKSNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKSRVVAQMGGERNFHIFYQLLAGADEALLQELRLERALDTYSYLTDGLNGTVTRINDADSFKQVQQALTVIDFTKEEQREIFGIVASILHLGNVGFTE-VEGNAKVNSRDLVVTAARLLGVNASELEAALTHRTIDA-----RGDVVTSPLNQELAIYARDALAKAVYDRLFSWLVQRLN--ISLQAKETRASRNNVMGILDIYGFEIFQKNSFEQFCINFCNEKLQQLFIELTLKSEQDEYRREGIEWIPVEYFDNKVICNLIEEKH--KGIISILDEECLRPGEP---TDKTFLEKLTQKLAQHHHYVCHEKAPAHIKKIMLRDEFRLVHYAGEVTYSVNGFLDKNNDLLFRDLKETLSKAGNGIVRNCFPE---KELRSLKRPETAITQFRASLNNLMDILMCKEPSYIRCIKPNDLQTANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYELFLERYKSLSKSTWPNYKG--PGGPKAGVQQLVKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAYQEKKHEIAAIIQAHWKGLMQR------------------RKYLKLRAQVIIMQSYCRRKLAQQAA---------------------------------------KKRREAADKIRAFIKGFITRNDAPNGFNEEFIANAKRMWLLRLAKELPTKVLDKS-----------WPHAPGHCEEASGILHRLHRLHLARIYRLKLTPQQKRQFELKVLAEKVFKGKKNNYASS---VSTWFQEDR------IPKEHIQRVNDFVASTFGSEQLKYQSFCTKFDR-----HGYKSRDRFILLSNKAIYVLDGKTYKQK---HRLPLDKI----DFTLTNHNDDLMVIRIP----LDLKKDKGDLILIIPRIIEFSTYIIDTVGTAS-IVSIVDRNSLEHNVVKGKGGVIDIQTG--AEPGVVRDKGHLVIIGTQ---------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **.*:.** : . : **:**: : *:**** * :*:**:::: : : *:. * .**::*:::. : : .. *::******:*** *:* :: ::: : : : :*: :: :*.:**:** *** **:****.***::*:*. * .* * *:****.*** : .**.** :**: **. : : * * : .: . *: .:.: : :*.:* :**: * . : . . * ** : * *. * : : .. * * :*****.:: .:* :::. :* :. : : :*:*********: *.***:***: ******:**:*.** **: * :* *.* ::**:**::*:*:* **:: ::: :*.:: : : *: * : ****.* *.:.*: ::*.* * *: . : .: : :*: : ** ** : . :*: * * *:* ****: : . ::: * **:.**** **:*:****:.:*: : *: *: :: * .* ::. : : * :.:*:: *.:** *. :. . :* : : .:: ::: : : : : : . . . :. . : : . : : . . * . . . .. * . : ", "identical_positions": 196, "similar_positions": 233, "identity": "15.48%" }, { "cls_id": "homologset.agr.SGD:S000004716", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80VQ0-1", "uniprot_id": "AL3B1_MOUSE", "id": "Q80VQ0-1", "name": "Aldehyde dehydrogenase family 3 member B1", "aln": "------------------------------------------------------------------MDSFEDKLQQLREAFKEG-RTRSAEFRAAQLQGLSHFLRDNKQQLQEALAQDLHKSAFEAEVSEIAISQAEVDLALRNLRSWMKDEKVS-KNLATQLDSAFIRKEPFGLVLIIVPWNYPINLTLVPLVGAIAAGNCVVLKPSEISKATEKILAEVLPRY-LDQSCFTVVLGGRQETGQLLEH-KFDYIFFTGNAYVGKIVMAAAAKHLTPITLELGGKNPCYVDD---NCDPQIVANRVAWFRYFNAGQTCVAPDYILCSQEMQERLVPALQNAITRFYGDNPQTSPNLGRIINQKHFKRLQG-LLGCGRVAIG------GQSDEGERYIAPTVLVDVQETEPVMQEEIFGPILPLVTVRSLDEAI-EFMNRREKPLALYAFSKRSQVIKQVLARTSSGGFCGNDGFMHMTLSSLPFGGVGTSGMGRYHGKFSFDTFSNQRACLLRSPG--MEKINDLRYPPYSSRNLRVLLVAMEERC------CSCTLL-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XI42-1", "uniprot_id": "AL3B1_RAT", "id": "Q5XI42-1", "name": "Aldehyde dehydrogenase family 3 member B1", "aln": "------------------------------------------------------------------MDSFEDKLQQLREAFNAG-RTRSAEFRAAQLQGLSHFLRDNKQQLQEALAQDLHKSAFESEVSEIAISQAEVDLALRNLRSWMKDEKVS-KNLATQLDSAFIRKEPFGLVLIIVPWNYPLNLTLVPLVGAIAAGNCVVLKPSEISKATEKILAEVLPRY-LDQSCFAVVLGGPQETGQLLEH-RFDYIFFTGNTYVGKIVMAAAAKHLTPITLELGGKNPCYVDD---NCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSQEMQERLVPALQNAITRFYGDNPQTSPNLGRIINQKHFERLQG-LLGCGRVAIG------GQSDEGERYIAPTVLVDVQETEPVMQEEIFGPILPLVTVTNLDEAI-EFINRREKPLALYAFSKRSQVIKQVLARTSSGGFCGNDGFMHMTLSSLPFGGVGTSGMGRYHGKFSFDTFSNQRACLLRSPG--MEKINDLRYPPYTSRNLRVLLVAMEKRC------CSCTLL-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43353-1", "uniprot_id": "AL3B1_HUMAN", "id": "P43353-1", "name": "Aldehyde dehydrogenase family 3 member B1", "aln": "------------------------------------------------------------------MDPLGDTLRRLREAFHAG-RTRPAEFRAAQLQGLGRFLQENKQLLHDALAQDLHKSAFESEVSEVAISQGEVTLALRNLRAWMKDERVP-KNLATQLDSAFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSEISKNVEKILAEVLPQY-VDQSCFAVVLGGPQETGQLLEH-RFDYIFFTGSPRVGKIVMTAAAKHLTPVTLELGGKNPCYVDD---NCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRA-LLGCGRVAIG------GQSDESDRYIAPTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAI-EFINRREKPLALYAFSNSSQVVKRVLTQTSSGGFCGNDGFMHMTLASLPFGGVGASGMGRYHGKFSFDTFSHHRACLLRSPG--MEKLNALRYPPQSPRRLRMLLVAMEAQG------CSCTLL-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9Q3E1-1", "uniprot_id": "AL3B2_MOUSE", "id": "E9Q3E1-1", "name": "Aldehyde dehydrogenase family 3 member B2", "aln": "-----------------------------------------------------MSAAETGSEPSQGAGPSEATLHSLREAFNAG-RTRPTEFRTAQLRSLGRFLQENKELLQDALAKDVGKSGFESDMSEIILCENEVDLALKNLQTWMKDEPVS-TNLLTKLSSAFIRKEPFGLVLIIAPWNYPVNLMIIPLVGAIAAGNCVVLKPSEISKNTEKVLAELLPQY-LDQSCFAVMLGGPEETRQLLEH-KFDYIFFTGSPRVGKIVMTAAAKHLTPITLELGGKNPCYVDD---NCDPQTVANRVAWFRYFNAGQTCVAPDYILCSQEMQERLVPALQNSITRFYGDNPQTSPNLGRIINQKHFKRLQG-LLGCGRVAIG------GQSDEGERYIAPTVLVDVQETEPVMQEEIFGPILPLVTVRSLDEAI-EFINRREKPLALYAFSNNNQVVNQMLERTSSGGFGGNDGFLYLTLPALPLGGVGNSGMGRYHGKFSFDTFSHHRACLLRSPG--MEKLNDLRYPPYGPWNQQLISWAIGSR--------SCTLL-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "J3QMK6-1", "uniprot_id": "AL3B3_MOUSE", "id": "J3QMK6-1", "name": "Aldehyde dehydrogenase family 3 member B3", "aln": "-----------------------------------------------------MSTKGKHPRADQGTDPFEEKLQRLKEAFNTG-KTKTAKFRAEQLQSLGRFLQDNSKQLHDALDGDLGKSGFESDMSEIILCENEVDLALKNLQTWMKDEPVS-TNLLTKLSTAFIRKEPFGLVLIIAPWNYPVNLMIIPLVGAIAAGNCVVLKPSEISKNTEKVLAELLPQY-LDQSCFAVMLGGPEETGQLLEH-KFDYIFFTGSPRVGKIVMTAAAKHLTPITLELGGKNPCYVDD---NCDPQTVANRVAWFRYFNAGQTCVAPDYILCSQEMQEQLVPALQNAITRFYGDNPQTSPNLGRIINQKHFKRLQG-LLGCGRVAIG------GQSDEGERYIAPTVLVDVQETEPVMQEEIFGPILPLVTVRSLDEAI-EFMNQREKPLALYAYSNNAEVIKQVLARTSSGGFCGNDGFMYMTLSSLPFGGVGSSGMGRYHGKFSFDTFSNQRACLLSCPG--MEKLNGLRYPPYSPRRQQLLRWAIGSE--------SCTLL-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48448-1", "uniprot_id": "AL3B2_HUMAN", "id": "P48448-1", "name": "Aldehyde dehydrogenase family 3 member B2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MKDEPRS-TNLFMKLDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQY-LDQSCFAVVLGGPQETGQLLEH-KLDYIFFTGSPRVGKIVMTAATKHLTPVTLELGGKNPCYVDD---NCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYGDDPQSSPNLGHIINQKQFQRLRA-LLGCSRVAIG------GQSNESDRYIAPTVLVDVQETEPVMQEEIFGPILPIVNVQSVDEAI-KFINRQEKPLALYAFSNSSQVVNQMLERTSSGSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAPSG--LEKLKEIHYPPYTDWNQQLLRWGMGSQ--------SCTLL-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47740-1", "uniprot_id": "AL3A2_MOUSE", "id": "P47740-1", "name": "Aldehyde dehydrogenase family 3 member A2", "aln": "---------------------------------------------------------------------MERQVLRLRQAFRSG-RSRPLRFRLQQLEALRRMVQEREKEILAAIAADLSKSELNAYSHEVITILGEIDFMLGNLPELASARPAK-KNLLTMMDEAYVQPEPLGVVLIIGAWNYPFVLTMQPLVGAIAAGNAAIVKPSELSENTAKILAELLPQY-LDQDLYAIVNGGIPETTELLKQ-RFDHILYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDR---DCDLDVACRRIAWGKYMNCGQTCIAPDYILCEASLQNQIVQKIKETVKDFYGENIKASPDYERIINLRHFKRLQS-LLKGQKIAFG------GEMDEATRYLAPTILTDVDPNSKVMQEEIFGPILPIVSVKNVDEAI-NFINDREKPLALYVFSRNNKLIKRVIDETSSGGVTGNDVIMHFTVNSLPFGGVGASGMGAYHGKYSFDTFSHQRPCLLKGLK--GESVNKLRYPPNSESKVSWAKFFLLKQ------FNKGRLGMLLFVCLVAVAAVIVKDQL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30839-1", "uniprot_id": "AL3A2_RAT", "id": "P30839-1", "name": "Aldehyde dehydrogenase family 3 member A2", "aln": "---------------------------------------------------------------------MERQVQRLRQTFRSG-RSRPLRFRLQQLEALRRMVQEREKDILAAIAADLSKSELNAYSHEVITILGEIDFMLGNLPELASARPAK-KNLLTMMDEAYVQPEPLGVVLIIGAWNYPFVLTLQPLVGAIAAGNAAIVKPSELSENTAKILAELLPQY-LDQDLYMIVNGGVEETTELLRQ-RFDHILYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDR---DCDLDVACRRITWGKYMNCGQTCIAPDYILCEASSQDQIVQKIKDTVKDFYGENVKASPDYERIINLRHFKRIKS-LLEGQKIAFG------GETDEATRYIAPTILTDVDPNSKVMQEEIFGPILPIVSVKNVEEAI-NFINDREKPLALYIFSHNNKLIKRVIDETSSGGVTGNDVIMHFTVNSLPFGGVGASGMGAYHGKYSFDTFSHQRPCLLKGLK--GESVNKLRYPPNSESKVSWSKFFLLKQ------FNKGRLQLLLLVCLVAVAAVIVKDQL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51648-1", "uniprot_id": "AL3A2_HUMAN", "id": "P51648-1", "name": "Aldehyde dehydrogenase family 3 member A2", "aln": "---------------------------------------------------------------------MELEVRRVRQAFLSG-RSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQEVITVLGEIDFMLENLPEWVTAKPVK-KNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQY-LDQDLYIVINGGVEETTELLKQ-RFDHIFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDK---DCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILS-LLEGQKIAFG------GETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAI-NFINEREKPLALYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFSHQRPCLLKSLK--REGANKLRYPPNSQSKVDWGKFFLLKR------FNKEKLGLLLLTFLGIVAAVLVKAEYY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47739-1", "uniprot_id": "AL3A1_MOUSE", "id": "P47739-1", "name": "Aldehyde dehydrogenase, dimeric NADP-preferring", "aln": "------------------------------------------------------------------MSNISSIVNRARDAFNSG-KTRPLQFRVEQLEALQRMINENLKGISKALASNLRKNEWTSYYEEVAHVLDEIDFTIKGLSDWAEDEPVA-KTRQTQEDDLYIHSEPLGVVLVIGAWNYPFNLTIQPMVGAIAAGNAVVLKPSEVSDHMADLLSTLIPQY-MDKDLYPVIKGGVPETTELLKE-KFDHIMYTGSTAVGKIVMAAAAKHLTPVTLELGGKSPCYVDK---DCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNEIVEKLKKSLKDFYGEDAKQSHDYGRIINDRHFQRVIN-LIDSKKVAHG------GTWDQPSRYIAPTILVDVDPQSPVMQEEIFGPVMPIVCVRSLDEAI-KFINQREKPLALYVFSNNDKVIKKMIAETSSGGVTANDVIVHITVPTLPFGGVGNSGMGAYHGKKSFETFSHRRSCLVRSLR--NEEANKARYPP-SPAKMPRH-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11883-1", "uniprot_id": "AL3A1_RAT", "id": "P11883-1", "name": "Aldehyde dehydrogenase, dimeric NADP-preferring", "aln": "------------------------------------------------------------------MSSISDTVKRAREAFNSG-KTRSLQFRIQQLEALQRMINENLKSISGALASDLGKNEWTSYYEEVAHVLEELDTTIKELPDWAEDEPVA-KTRQTQQDDLYIHSEPLGVVLVIGAWNYPFNLTIQPMVGAVAAGNAVILKPSEVSGHMADLLATLIPQY-MDQNLYLVVKGGVPETTELLKE-RFDHIMYTGSTAVGKIVMAAAAKHLTPVTLELGGKSPCYVDK---DCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKDFYGEDAKQSRDYGRIINDRHFQRVKG-LIDNQKVAHG------GTWDQSSRYIAPTILVDVDPQSPVMQEEIFGPVMPIVCVRSLEEAI-QFINQREKPLALYVFSNNEKVIKKMIAETSSGGVTANDVIVHITVPTLPFGGVGNSGMGAYHGKKSFETFSHRRSCLVKSLL--NEEAHKARYPP-SPAKMPRH-------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30838-1", "uniprot_id": "AL3A1_HUMAN", "id": "P30838-1", "name": "Aldehyde dehydrogenase, dimeric NADP-preferring", "aln": "------------------------------------------------------------------MSKISEAVKRARAAFSSG-RTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVE-KTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNSVVLKPSELSENMASLLATIIPQY-LDKDLYPVINGGVPETTELLKE-RFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDK---NCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMG-LIEGQKVAYG------GTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAI-QFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLM--NDEGLKVRYPP-SPAKMTQH-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B720-1", "uniprot_id": "A0ACD6B720_DANRE", "id": "A0ACD6B720-1", "name": "Aldehyde dehydrogenase", "aln": "--------------------------------------------------------------------MEKQVVDGLREVFQSG-RSRPLQYRKQQLRALLRLITERHADIEQALKQDLNRSMHGTSLFELIGIENDIKVAEREMTEWAAPRPVK-KNLNSALDDVYVKPEPLGVVLIIGTWNYPWAMIFQPLVGAIAAGNAAVVKPSELSEHSSRLMKELLPLY-LDKEMYQVVTGGVPETQELLKQ-RFDHIFYTGSSTVGKLVMEAASRHLTPVTLELGGKSPCYIDK---NCDIAVACRRITWGKFANCGQTCIAPDYILCEPSIQDRIVEEIQKTLLEFYQTDPKSSPDYCRIINTRHFDRVLA-LMNECTIALG------GENDRSQCYIAPTVLKDVLPHFKIMQEEIFGPLLPIVTVNGLSEAI-NFINAREKPLALYVFSSDKTVIKRMLKETTSGGVTVNDVLMHYTVDTLPFGGVGNSGMGRYHGKHTFDQLSHHRACLIKSFA--MESLNDARYPPLTTARLRKAKFFMGHR------MCSCNGMCVWAVIATVLAIGLLVGLLVVLI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0C4DHC8-1", "uniprot_id": "A0A0C4DHC8_DROME", "id": "A0A0C4DHC8-1", "name": "", "aln": "MFDNAIKPHPEANGAPINAAGDRPITTVINIEPEPETESPIGIFTSQPESQQQQPEQLQSESESDRMANFDDTLQRARLAFSSG-KTRNVSFRRKQLENLLRCYEEHENEIISALEADLRRPKQESLIVETEFMKNDIRHILFQLDEWVQSEKPP-KSFVNMMDDVQIYNDPFGVVLVIGAWNYPLQLLLVPVASAIAAGNCVVIKPSEIAANCAKFIADVIPKY-LDNDCYPVVCGGPSETAELLNQ-RFDYIFYTGSTRVGKIIHAAANKYLTPTTLELGGKSPCYIDK---SVDMRTAVKRILWGKLINCGQTCIAPDYILCSKEVQEKFIVEAKDVLKEWYGENIQSSPDLSRVINANNFQRLLG-LMKSGRVAVG------GNYDASERFIEPTILVDVKETDPIMEEEIFGPILPIFNVESAYDAI-KFINAREKPLVIYVFSNSNKLVKEFRRSTTSGGFSSNETIMHCGVDVLPFGGVGMSGMGRYHGKYGFETFTHKKSCLGKDLSPLGEKLSSARYPPYSDRKGSLLSFLLRKRRPLPNLHLSHVLAIGLGVGLTVLTNYYLQGKLLSK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M3ASB8-1", "uniprot_id": "A0A8M3ASB8_DANRE", "id": "A0A8M3ASB8-1", "name": "Aldehyde dehydrogenase", "aln": "-------------------------------------MSSPPSPSPTRWFKALRRSRVEDVCVKTGVSVCSEVLRRARAAFSAG-RTAQDTFRLAQLEALLRMLMDHECDFVDALGRDVHKPRFETVMSELLVVKNEALHAISNLKKWMEPQRIE-RDWATAFDECVLVNEPLGLVLIIGNWTSPLQLCLVPLVGAIAAGNCAIISPSETCTHTAGLLHRLIPAY-LDNECFHSVIAAAHEIPEIVDL-TFDYVFFSGDKEDGIKVAQAAARTLARVTLVLRVKNPCYVDS---QCDINTTARRITWARFHNAGQSAVAPDYILCHAEVKENLLQALRCSLQQFYGTDPRESRSFGRIVNEENFSKAKEQLWGSGKVIIG------GQVNEIERYIAPTVLMDVMESDPIMHQDVFGPILPILTVQDADEAV-AFINSREKPLCVYAYSSNNKVISKIMNETSSGSFCSNDSVLQSVMVGLPFGGVGASGMGSYHGRYSFDAFSHKKSCLLRSTR--IECMTVLRYPPYEDRNLSLVSLASFLNLKG---QGWCTIL-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04458-1", "uniprot_id": "HFD1_YEAST", "id": "Q04458-1", "name": "Fatty aldehyde dehydrogenase HFD1", "aln": "--------------------------------------------MSNDGSKILNYTPVSKIDEIVEISRNFFFEKQLKLSHENNPRKKDLEFRQLQLKKLYYAVKDHEEELIDAMYKDFHRNKIESVLNETTKLMNDILHLIEILPKLIKPRRVSDSSPPFMFGKTIVEKISRGSVLIIAPFNFPLLLAFAPLAAALAAGNTIVLKPSELTPHTAVVMENLLTTAGFPDGLIQVVQGAIDETTRLLDCGKFDLIFYTGSPRVGSIVAEKAAKSLTPCVLELGGKSPTFITENFKASNIKIALKRIFFGAFGNSGQICVSPDYLLVHKSIYPKVIKECESVLNEFYP-SFDEQTDFTRMIHEPAYKKAVASINSTNGSKIVPSKISINSDTEDLCLVPPTIVYNIGWDDPLMKQENFAPVLPIIEYEDLDETINKIIEEHDTPLVQYIFSDSQTEINRILTRLRSGDCVVGDTVIHVGITDAPFGGIGTSGYGNYGGYYGFNTFSHERTIFKQPYWN--DFTLFMRYPPNSAQKEKLVRFAMERKPWFDRNGNNKWGLRQYFSLSAAVILISTIYAHCSS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . * **:* :. * : : : .*:***. ::.*** .: ::. . . : .. * .:: :* ::::*. * : * : *: .* * *.* :: : . .*: : *.** .::***:* . ..: . : :* . . . ::: :.: : . : **:: :: :*.:: *.*::*:. . ::: ::: ::.** * :* :... **. .: . : *:**:* ** * * * *: :::.:. : : :*** . ", "identical_positions": 56, "similar_positions": 117, "identity": "9.66%" }, { "cls_id": "homologset.agr.SGD:S000004720", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIJ1-1", "uniprot_id": "HMCES_RAT", "id": "Q5XIJ1-1", "name": "Abasic site processing protein HMCES", "aln": "MCGRTSCHLPRD---ALTRACAYLDRQGRRQ------------------LPQWRDPD----KYCPSYNKSPQSSSPVLLSRLHFEKDADS-SDRIIFPMRWGLVPSWFKESDPSKLQFNTSNCRSDTIMEKQSFKAPLGKGRRCVVLADGFYEWQRCQGTN---QRQPYFIYFPQSKTEKSGENSGSDSLNNKEEVWDNWRLLTMAGIFDCWEPP-KGERLYSYSIITVDSCRGLSDIHSRMPAILD-GEEAVSKWLDFGEVS--TQEALKLIHP---IDNITFHPVSPVVNNSRNNTPECLAPAD------LLVKKEPKASGSSQRMMQWLATKSPKKEVPDSPK---KDASGLPQWSSQFLQKSP--LPTKRGASSSLLDRWLKQEKEDEPVAKRPNS----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1M0-1", "uniprot_id": "HMCES_MOUSE", "id": "Q8R1M0-1", "name": "Abasic site processing protein HMCES", "aln": "MCGRTSCHLPRE---VLTRACAYQDRQGRRR------------------LPQWRDPD----KYCPSYNKSPQSSSPVLLSRLHFEKDADS-SDRIIIPMRWGLVPSWFKESDPSKLQFNTTNCRSDTIMEKQSFKVPLGKGRRCVVLADGFYEWQRCQGTN---QRQPYFIYFPQIKTEKSGGNDASDSSDNKEKVWDNWRLLTMAGIFDCWEAP-GGECLYSYSIITVDSCRGLSDIHSRMPAILD-GEEAVSKWLDFGEVA--TQEALKLIHP---IDNITFHPVSPVVNNSRNNTPECLAPAD------LLVKKEPKANGSSQRMMQWLATKSPKKEVPDSPK---KDASGLPQWSSQFLQKSP--LPAKRGATSSFLDRWLKQEKEDEPMAKKPNS----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96FZ2-1", "uniprot_id": "HMCES_HUMAN", "id": "Q96FZ2-1", "name": "Abasic site processing protein HMCES", "aln": "MCGRTSCHLPRD---VLTRACAYQDRRGQQR------------------LPEWRDPD----KYCPSYNKSPQSNSPVLLSRLHFEKDADS-SERIIAPMRWGLVPSWFKESDPSKLQFNTTNCRSDTVMEKRSFKVPLGKGRRCVVLADGFYEWQRCQGTN---QRQPYFIYFPQIKTEKSGSIGAADSPENWEKVWDNWRLLTMAGIFDCWEPPEGGDVLYSYTIITVDSCKGLSDIHHRMPAILD-GEEAVSKWLDFGEVS--TQEALKLIHP---TENITFHAVSSVVNNSRNNTPECLAPVD------LVVKKELRASGSSQRMLQWLATKSPKKEDSKTPQ---KEESDVPQWSSQFLQKSP--LPTKRG-TAGLLEQWLKREKEEEPVAKRPYSQ---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHI3-1", "uniprot_id": "Q9VHI3_DROME", "id": "Q9VHI3-1", "name": "Abasic site processing protein HMCES", "aln": "MCGRTCLTLDPD---QVICACKYPKKSTRKEPDFKEKDDMKDGEGSEMETPEWRAEYNLGRRYQASYNIAPTDITPVIVSAAHFSDAEDQECARVVTPMMWGMIPFWHKG-DYRRHGLTTNNCRLEHLMDSKLYRGPFKRGQRCVVICEGFYEWQTAGPAKKPSEREAYLVFVPQAADVKIYDKNTWSPQD--------VKLLRMAGLFDVWEDE-SGDKMYSYSIITFQSSKIMSWMHYRMPAILE-TEQQMNDWLDFKRVS--DKEALATLRP---ATELQWHRVTKLVNNSRNKSEECNKPIE------LAAK--PAKPPMNKTMMSWLNARKKREDQIKAKQ---SDDEDQEKEATTMGGTSADGSPVERPAKRPRFRDFKRNRTAAPPQSSGS------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04471-1", "uniprot_id": "YM04_YEAST", "id": "Q04471-1", "name": "Abasic site processing protein YMR114C", "aln": "MCGRFALAYDSGDLPQLLRDWNLPVNTPKDAS-----------------SNSQHPHDEEDTKDQPTVSKDIFKAS-YNISPTNYSAVYRP-DTKAIQFMRWGLVPFWTKDVSQFKT-YRTFNARLENLQESKMWMRPCEK-KRCAVLMSGYFEWKTVGKKK-----TPYFISRRDG------------------------RLMFVAGMYDYVEKD----DLYTFTIITAQGPRELEWLHERMPCVLEPGTESWDAWMDVDKTTWSTEELVKLLKPDYDESKLQFYQVTDDVGKTTNTGERLIKPLLKEDSDMFSVKREKEEALLENDNEQGIDNRGVKGDKSLKGEDVFNQKKSLKRNSYDGLKKNEEQEETTLPEEGSIGDRVKREEANLSPKREGNREKRNIVNMLGNQKDSRGKKKIKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** . : . : . : : .: . . : :* ::. : : * **::* * * . : * *.* : : :.: : * : :**.*: .*::**: : .*:: : :*: :**::* * :*:::*** :. : :. :* ***.:*: : . *:*. ..: :* : ::* :: :: *: *.:: *. . * : .* .: . : : : : : .: .. : : .. . :.. * . ", "identical_positions": 46, "similar_positions": 104, "identity": "10.9%" }, { "cls_id": "homologset.agr.SGD:S000004722", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63244-1", "uniprot_id": "RACK1_HUMAN", "id": "P63244-1", "name": "Small ribosomal subunit protein RACK1", "aln": "--MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDE-TNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPN----SSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIGTR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P68040-1", "uniprot_id": "RACK1_MOUSE", "id": "P68040-1", "name": "Small ribosomal subunit protein RACK1", "aln": "--MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDE-TNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPN----SSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIGTR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63245-1", "uniprot_id": "RACK1_RAT", "id": "P63245-1", "name": "Small ribosomal subunit protein RACK1", "aln": "--MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDE-TNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPN----SSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIGTR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O42248-1", "uniprot_id": "GBLP_DANRE", "id": "O42248-1", "name": "Small ribosomal subunit protein RACK1", "aln": "--MTEQMTVRGTLKGHSGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDE-TNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIQDDSHTEWVSCVRFSPN----SSNPIIVSCGWDKMVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDTINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELRQDIITTNSKAEPPQCTSLAWSADGQTLFAGYTDNLIRVWQVTIGTR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O18640-1", "uniprot_id": "GBLP_DROME", "id": "O18640-1", "name": "Small ribosomal subunit protein RACK1", "aln": "--MSETLQLRGTLIGHNGWVTQIATNPKDPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWVSCVRFSPN----HSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLEHNDIINALCFSPNRYWLCVAYGPSIKIWDLACKKTVEELRPEVVSPTSKADQPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSVSAH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38011-1", "uniprot_id": "GBLP_YEAST", "id": "P38011-1", "name": "Small ribosomal subunit protein RACK1", "aln": "MASNEVLVLRGTLEGHNGWVTSLATSAGQPNLLLSASRDKTLISWKLTGDD-QKFGVPVRSFKGHSHIVQDCTLTADGAYALSASWDKTLRLWDVATGETYQRFVGHKSDVMSVDIDKKASMIISGSRDKTIKVWTIKGQCLATLLG--HNDWVSQVRVVPNEKADDDSVTIISAGNDKMVKAWNLNQFQIEADFIGHNSNINTLTASPDGTLIASAGKDGEIMLWNLAAKKAMYTLSAQDEVFSLAFSPNRYWLAAATATGIKVFSLDPQYLVDDLRPEFAG-YSKAAEPHAVSLAWSADGQTLFAGYTDNVIRVWQVMTAN-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* : :**** **.****.:**.. *: ::*******:* **** *: ::* * : : ****::.* .:::** :***.*** ******:::* * :** **..**:** :. . *:*********:*. . * *: *.:*** **. ** .. *:*.* *: **.*** : ::: :. **.. :**:*.****:* :*.***.: :**:* * :***. * : :*.********..* ...**::.* : *::*: :. *** *:. *****:*********:** :***** . ", "identical_positions": 150, "similar_positions": 93, "identity": "46.3%" }, { "cls_id": "homologset.agr.SGD:S000004724", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q641Z9-1", "uniprot_id": "Q641Z9_RAT", "id": "Q641Z9-1", "name": "Succinate dehydrogenase cytochrome b560 subunit, mitochondrial", "aln": "--MAALLLRHIGRHCLRAHLS-SQLCIRNAAPLGTTAKEEMAR-------------------------------FWNKN--------TSSNRPVSPHLTIYRWSLPMAMSVCHRGSGIAMSGGVSLF----GLSALLLPGNFESYLMLVKSLCLGPALIHAAKFVLVFPLMYHSLNGVRHLMWDLGKGLSISQVQLSGVTVLVLAVLSSAGLAAI-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CZB0-1", "uniprot_id": "C560_MOUSE", "id": "Q9CZB0-1", "name": "Succinate dehydrogenase cytochrome b560 subunit, mitochondrial", "aln": "--MAAFLLRHVSRHCLRAHLN-AQLCIRNAAPLGTTAKEEMER-------------------------------FWKKN--------TSSNRPLSPHLTIYKWSLPMALSVCHRGSGIALSGGVSLF----GLSALLLPGNFESYLMFVKSLCLGPTLIYSAKFVLVFPLMYHSLNGIRHLLWDLGKGLAIPQVWLSGVAVVVLAVLSSGGLAAL-----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99643-1", "uniprot_id": "C560_HUMAN", "id": "Q99643-1", "name": "Succinate dehydrogenase cytochrome b560 subunit, mitochondrial", "aln": "--MAALLLRHVGRHCLRAHFS-PQLCIRNAVPLGTTAKEEMER-------------------------------FWNKN--------IGSNRPLSPHITIYSWSLPMAMSICHRGTGIALSAGVSLF----GMSALLLPGNFESYLELVKSLCLGPALIHTAKFALVFPLMYHTWNGIRHLMWDLGKGLKIPQLYQSGVVVLVLTVLSSMGLAAM-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S5Q2-1", "uniprot_id": "B0S5Q2_DANRE", "id": "B0S5Q2-1", "name": "Succinate dehydrogenase cytochrome b560 subunit, mitochondrial", "aln": "---MALLLRTVARQGLYSSRSQFGVLYRHAVPMGTTSNEEMDK-------------------------------FWAKN--------TRLNRPMSPHMTIYKWSVPMAMSISHRGTGIALSSGISAF----ALAALVLPESYPYYLDLIHSLTFGPQFLAFSKFALAFPVVYHTYNGIRHLAWDAGKGFKIPEVYRSGYVVLGLTVLTSIGLAAM-----------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGS3-1", "uniprot_id": "Q9VGS3_DROME", "id": "Q9VGS3-1", "name": "", "aln": "--MYALSSSLIRSPALRQGLQMAAASRPVSMKVVSVAETQKDES------------------------------FFEKN--------ERLGRELSPHLTIYQPQLTSMLSICHRGTGLALGVGVWGL----GLGALISSHDISHYVTMVEGLQLSGATLTALKFIIAYPAGYHTANGIRHLLWDTGRFLKIKEVYSTGYAMVATSFVLSAILALL-----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT9-1", "uniprot_id": "Q9VGT9_DROME", "id": "Q9VGT9-1", "name": "", "aln": "MNTCRSLARGLNICSPQLRHLLAQKPFNSARLLATKAPKDHKASGPTTIGPSGDILVPPVTLKVIPFRMPPDLPYDDRN--------MLLGRQLSPHLSIYKIQLTSTLSAFLRISGFVLAVFVWFV----GISGLCLQGDMEGFIKKVEKCDCHG-MVTMAKVMVTMPFAYHTVAGTRHLIWYLNKFLTIPEIYATGYVAVALTIALSAFLLAVKVGEKVKEEVVDLTKTKKGQKAKKEAPKDAKKDAPKDTKKEPKKDAKDKKKDEEGKSAK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04487-1", "uniprot_id": "SHH3_YEAST", "id": "Q04487-1", "name": "Mitochondrial inner membrane protein SHH3", "aln": "--MKATIQRVTSVFGVPRASVFVPRISTPFILHNYISNGRMDLFSKEFHNG-----------------RVSKSDLWSSNKEEELLVSQRKKRPISPHLTVYEPEMSWYLSSLHRISGVLLALGFYAFTITLGVTTIMGMDTTFQDLNKWYHEKMPKWSQWVAKGSAAYLFAFHFGNGIRHLIWDMGYELTNRGVIKTGSIVLAGTLVLGTYLLAQ-----------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * :***:::* .:. :* * :*. :. . . .: : : * . :* * *** * . : : :* : :. . * ", "identical_positions": 18, "similar_positions": 29, "identity": "6.57%" }, { "cls_id": "homologset.agr.SGD:S000004727", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35567-1", "uniprot_id": "PUR9_RAT", "id": "O35567-1", "name": "Bifunctional purine biosynthesis protein ATIC", "aln": "MA-SSQLALFSVSDKTGLVEFARNLASLGLSLVASGGTAKAIRDAGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILARNIPEDAADMARLDFNLIRVVVCNLYPFVKTVASPDVTVEAAVEQIDIGGVTLLRAAAKNHARVTVVCEPEDYGAVAAEMQGSGNKDTSLETRRHLALKAFTHTAQYDEAISDYFRRQYSKGISQMPLRYGMNPHQTPAQLYT-LKPKLPITVLNGAPGFINLCDALNAWQLVTELRGAVDIPAAASFKHVSPAGAAVGVPLSEDEARVCMVYDLYPTLTPLAIAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIVAPGYEEEALKILSKKKNGSYCVLQMDQSYKPDENEVRTLFGLRLSQKRNNGVVDKSLFSNIVTKNKDLPESALRDLIVATIAVKYTQSNSVCYAKDGQVIGIGAGQQSRIHCTRLAGDKANSWWLRHHPRVLSMKFKAGVKRAEVSNAIDQYVTGTIGEGED-LVKWKALFEEVPELLTEAEKKEWVDKLSGVSVSSDAFFPFRDNVDRAKRSGVAYIVAPSGSTADKVVIEACDELGIVLAHTDLRLFHH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWJ9-1", "uniprot_id": "PUR9_MOUSE", "id": "Q9CWJ9-1", "name": "Bifunctional purine biosynthesis protein ATIC", "aln": "MA-PSQLALFSVSDKTGLVEFARSLASLGLSLVASGGTAKAIRDAGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILARNIPEDAADMARLDFNLVRVVVCNLYPFVKTVASPDVTVEAAVEQIDIGGVTLLRAAAKNHARVTVVCEPEDYAGVAAEMHGSDSKDTSLETRRHLALKAFTHTAQYDEAISDYFRKQYSKGISQMPLRYGMNPHQTPAQLYT-LKPKLPITVLNGAPGFINLCDALNAWQLVTELRGAVDIPAAASFKHVSPAGAAVGVPLSEDEARVCMVYDLYPTLTPLAVAYARARGADRMSSFGDFVALSDICDVPTAKIISREVSDGIVAPGYEEEALKILSKKKNGNYCVLQMDQSYKPDENEVRTLFGLRLSQKRNNGVVDKSLFSNIVTKNKDLPESALRDLIVATVAVKYTQSNSVCYAKDGQVIGIGAGQQSRIHCTRLAGDKANSWWLRHHPRVLSMKFKAGVKRAEISNAIDQYVTGTIGEGED-LVKWEALFEEVPELLTEAEKKEWVDKLSGVSVSSDAFFPFRDNVDRAKRSGVAYIVAPSGSTADKVVIEACDELGIVLAHTDLRLFHH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31939-1", "uniprot_id": "PUR9_HUMAN", "id": "P31939-1", "name": "Bifunctional purine biosynthesis protein ATIC", "aln": "MA-PGQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSKGVSQMPLRYGMNPHQTPAQLYT-LQPKLPITVLNGAPGFINLCDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVTKNKDLPESALRDLIVATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKTGVKRAEISNAIDQYVTGTIGEDED-LIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDAFFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VC18-1", "uniprot_id": "Q9VC18_DROME", "id": "Q9VC18-1", "name": "Bifunctional purine biosynthesis protein ATIC", "aln": "MS-SSKIALLSVSDKTGLLDLGKSLVALGFDLVASGGTATSLRGAGLKVRDVSEITGAPEMLGGRVKTLHPAVHAGILSRTTDSDLADMRKQGFDLIQLVVCNLYPFASTVAKPDVTLADAVENIDIGGVTLLRAAAKNHQRVTVVCEAVDYDRVLSELKASGN--TTVETRQALALKAFTHTATYDDAISDYFRKQYGSGVSQLPLRYGMNPHQKPAQLYT-QLAKLPLTVLNASPGFINLCDALNGWQLVRELKKALQLPAATSFKHVSPAGAAVGVPLNPAQAKLCMVDDLYEQLTPLATAYARARGADRMSSFGDFVALSDVCDVVTARIISREVSDGIIAAGYEPEALEILKKKKNGGYCILQMDPNYEPSAVERKTIFGLTLEQKRNDAVIDASLFSNVVSKRGPLPEVAVRDLIVATIALKYTQSNSVCYARDGQVVGIGAGQQSRIHCTRLAGEKADNWWLRQHPSVAGMKFKAGVKRAEISNAIDNYVNGTVGKDMP-LSQFEGMFDKAPAQLTSEQKVEWLKQLSGVALGSDAFFPFRDNIDRASLSGVSYIASPAGSTNDAGVIAACDEHGIIMAHTNLRLFHH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38009-1", "uniprot_id": "PUR92_YEAST", "id": "P38009-1", "name": "Bifunctional purine biosynthesis protein ADE17", "aln": "MANYTKTAILSVYDKTGLLDLARGLIEKNVRILASGGTARMIRDAGFPIEDVSAITHAPEMLGGRVKTLHPAVHGGILARDIDSDEKDLKEQHIEKVDYVVCNLYPFKETVAKVGVTIPEAVEEIDIGGVTLLRAAAKNHARVTILSDPKDYSEFLSELSSNGE--ISQDLRNRLALKAFEHTADYDAAISDFFRKQYSEGQAQITLRYGANPHQKPAQAYVSQQDSLPFKVLCGSPGYINLLDALNSWPLVKELSASLNLPAAASFKHVSPAGAAVGIPLSDVEKQVYFVADIEN-LSPLACAYARARGADRMSSFGDWIALSNIVDVPTAKIISREVSDGVIAPGYEPEALAILSKKKGGKYCILQIDPNYVPEAVERRQVYGVTLEQKRNDAIINQSTFKEIVSQNKNLTEQAIIDLTVATIAIKYTQSNSVCYARNGMVVGLGAGQQSRIHCTRLAGDKADNWWFRQHPRVLEIKWAKGVKRPEKSNAIDLFVTGQIPTEEPELSEYQSKFEEIPKPFTPEERKEWLSKLTNVSLSSDAFFPFPDNVYRAVKSGVKYIAAPSGSVMDKVVFSAADSFDLVYVENPIRLFHH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : *::** *****:::.:.* .. ::****** :*.**: :.*** :* ****************.***:* .* *: . :: : *.****** .***. .**: ***:**************** ***::.:. ** . :*: .. . : : *. ****** *** ** ****:**:**..* :*:.**** ****.*** *. .**:.** .:**:*** ****.* ** ** :: :***:*************:**. : :: :* *: *:*:: ****************::***:: ** **:*********::*.*** *** **.***.* **:**:* .* *. * : ::*: *.****:.::: * *.::*::. *.* *: ** ***:*:***********::* *:*:***************:**: **:*:** * :*: ****.* ***** :*.* : * :::. *:: * :* :: **:.:*: *::.******* **: ** *** **.:*:**. * *: *.*. .:: ... :*****", "identical_positions": 313, "similar_positions": 157, "identity": "52.61%" }, { "cls_id": "homologset.agr.SGD:S000004728", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CZM2-1", "uniprot_id": "RL15_MOUSE", "id": "Q9CZM2-1", "name": "Large ribosomal subunit protein eL15", "aln": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61313-1", "uniprot_id": "RL15_HUMAN", "id": "P61313-1", "name": "Large ribosomal subunit protein eL15", "aln": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61314-1", "uniprot_id": "RL15_RAT", "id": "P61314-1", "name": "Large ribosomal subunit protein eL15", "aln": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O17445-1", "uniprot_id": "RL15_DROME", "id": "O17445-1", "name": "Large ribosomal subunit protein eL15", "aln": "MGAYRYMQELYRKKQSDVMRYLLRIRVWQYRQLTKLHRSPRPTRPDKARRLGYRAKQGFVIYRIRVRRGGRKRPVPKGCTYGKPKSHGVNQLKPYRGLQSIAEERVGRRLGGLRVLNSYWIAQDASYKYFEVILIDTHHSAIRRDPKINWICKHVHKHRELRGLTSAGKSSRGIGKGYRYSQTIGGSRRAAWKRKNREHMHRKR-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54780-1", "uniprot_id": "RL15B_YEAST", "id": "P54780-1", "name": "Large ribosomal subunit protein eL15B", "aln": "MGAYKYLEELERKKQSDVLRFLQRVRVWEYRQKNVIHRAARPTRPDKARRLGYKAKQGFVIYRVRVRRGNRKRPVPKGATYGKPTNQGVNELKYQRSLRATAEERVGRRAANLRVLNSYWVNQDSTYKYFEVILVDPQHKAIRRDARYNWICNPVHKHREARGLTATGKKSRGINKGHKFNNTKAG-RRKTWKRQNTLSLWRYRK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:*::** *******:*:* *:* *:*** . :**:.*************:****:****:*****.********.***** :***:** *.*:: ****.**: . ********: :*::**:*****:*. *.****:. :** : ****** ****::*:.***:.**::: :* .* ** :*:*:* : * * ", "identical_positions": 125, "similar_positions": 51, "identity": "60.98%" }, { "cls_id": "homologset.agr.SGD:S000004732", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q56A27-1", "uniprot_id": "NCBP1_RAT", "id": "Q56A27-1", "name": "Nuclear cap-binding protein subunit 1", "aln": "--MSRRRHSYENDGGQPHKR---RKTSDANETEDHLESLICKVGEK--SACSLESNLEGLAGVLEADLP---NYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANN-------------YNEAVYLVRFLSDLVNCHVIAAPS--MVAMFENFVSVTQEEDVPQVRRDWYVYA-FLSSLPWVGKELYEKKDAEMDRIFSSTESYLKR---RQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLKKDRWQER--------HILRPYLA---FDSILCEALQHNLPPFTPPPH---TEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHCIIKSYWKERKTCAAQLVSY--------------------------PGKNKIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMSTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLTQDLE---SPKPKFVREVLEKCMRLS-YHQHILDIVPPTFSALCPANPTCIYKYGDESSNSLPGHSVALCLS---------------------VAFKSKATNDEIFSILKDVPNPNQVDDDDEGFRFNPLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAE-----SDKGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRGSDRK-------DGALEEQIERLQEKVESAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSILTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILAVFQQFCALQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UYV9-1", "uniprot_id": "NCBP1_MOUSE", "id": "Q3UYV9-1", "name": "Nuclear cap-binding protein subunit 1", "aln": "--MSRRRHSYENDGGQPHKR---RKTSDANETEDHLESLICKVGEK--SACSLESNLEGLAGVLEADLP---NYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANN-------------YNEAVYLVRFLSDLVNCHVIAAPS--MVAMFENFVSVTQEEDVPQVRRDWYVYA-FLSSLPWVGKELYEKKDAEMDRIFSTTESYLKR---RQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLKKDRWQER--------HILRPYLA---FDSILCEALQHNLPPFTPPPH---TEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHCIIKSYWKERKTCAAQLVSY--------------------------PGKNKIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMSTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLTQDLE---SPKPKFVREVLEKCMRLS-YHQHILDIVPPTFSALCPANPTCIYKYGDESSNSLPGHSVALCLS---------------------VAFKSKATNDEIFSILKDVPNPNQVDDDDEGFRFNPLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAE-----SDKGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRK-------DGALEEQIERLQEKVEAAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSILTPWYKNCIERLQQIFLQHHQTIQQYMVTLENLLFTAELDPHILAVFQQFCALQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q09161-1", "uniprot_id": "NCBP1_HUMAN", "id": "Q09161-1", "name": "Nuclear cap-binding protein subunit 1", "aln": "--MSRRRHSDENDGGQPHKR---RKTSDANETEDHLESLICKVGEK--SACSLESNLEGLAGVLEADLP---NYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANN-------------YNEAVYLVRFLSDLVNCHVIAAPS--MVAMFENFVSVTQEEDVPQVRRDWYVYA-FLSSLPWVGKELYEKKDAEMDRIFANTESYLKR---RQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLKKDRWQER--------HILRPYLA---FDSILCEALQHNLPPFTPPPH---TEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHCIIKSHWKERKTCAAQLVSY--------------------------PGKNKIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMNTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLSQDPE---SPKPKFVREVLEKCMRLS-YHQRILDIVPPTFSALCPANPTCIYKYGDESSNSLPGHSVALCLA---------------------VAFKSKATNDEIFSILKDVPNPNQDDDDDEGFSFNPLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAE-----SDEGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRK-------DGVLEEQIERLQEKVESAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILAVFQQFCALQA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7K4N3-1", "uniprot_id": "NCBP1_DROME", "id": "Q7K4N3-1", "name": "Nuclear cap-binding protein subunit 1", "aln": "--MSRRRAHDTEDEGYDHRRNKRRRVSENQEIEDRLESLILRVGER--STSSVESNLEGLVSVLEADLG---TFRLKILRILSDCAVRMPEKCTVYTTLVGLLNAKNYKFGGEFVDHMVKTFKESLKMCR-------------WDAARYSLRFLADLVNCHVISATS--LLQLLDTMIDVSNEDTVPQVRRDWFVFA-VLSTLPWVGRDLYEKKESALESLLLRIEVYLNK---RSKKHHNALRVWSSDAPHPQEEYLDCLWAQIRKLRQDNWAEK--------HIPRPYLV---FDSILCEALQHNLPTIVPPPH---HDNFEYPMPWVVYRMFDYTDCPDGPNLPGAHSIERFLIEEHLHHIIETYHHERKDCAAQLLSF--------------------------PYKHKIPLEYCIVEVVFAELFHMPTPRYLDICYGSILIELCKLQPATLPQVLAQATEILFMRIDSMNTSCFDRFVNWFSYHLSNFKFTWSWDEWDSCLLLDGE---HPRPKFIQEVLQKCLRLS-YHQRITEMMPTTYAKLIPLTPVPNYKYANEEAANLPGTTVAHQLV---------------------VAIRQKCTPEEVVNILKDIPNSGYSGEEMSDGSFNALKIDVFVQTLLNLGSKSFSHSFAAISKFHSVFRALAE-----TEEAQICILHNIFELWSSHQQMMVVLIDKLLKLQIVDCSAVATWIFSKEMTGEFTKLYLWEILHLTIKKMNKHVIKLNTELSEAKEKLAKADSSSSDSEDDSSHKRKKPITHADKPSEEVVERMEEKLEAANVNQKRLFLIVFQRFIMILSEHLLRSDTDGRDPDTDWYRWTIGRLQQVFLMHHEQVQKYSSTLETLLFTSDLDTHILEVFQQFVALRA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34160-1", "uniprot_id": "NCBP1_YEAST", "id": "P34160-1", "name": "Nuclear cap-binding protein complex subunit 1", "aln": "MFNRKRRGDFDEDENYRDFRPRMPKRQRIPPVVQLCKEMMPDIRTIGESVKAFEDDIKFLSEAIMNEYGHEDYFNNALLSTLNAVVVEQPQKQAAIALLTMVVNSKNNVAGKSIINYFFEELQKWCKQTYNDEFKSTSNETGPWNKIKLILRFLSILSPMFLVDELINIYKSLFELSIELNNLDPGNRVPLSEAIYTNTLLNIPYL--FFFNRNNDGLRTKVEELLAYVEQNYLVKTTDINLLREYNGEPPYEMVELVRVVLPNVKKALINNLEQLNELFPDWNHLLTPQTGDEGFNDALTLPSVDDLKSFVRLNKNFGSVDSMWKTPRYAFHVYLPNSAGNFETVVPISTYAGQLFNDIIIDLVESLEFNRKEVARQVITLDLFFKAGIFTEPGESIAQLIATYEENPLAPTFKIEDLAIETILGLIFKLPSVSQPFAYFYTLLVDICQNSPKAIAPVFGRAFRFFYSHLDSLDFELKLRYLDWFSIQMSNFNFSWKWNEWEDDSIKFGKYFYNPKVNFAKNLIQKELRLTSNFSEVEDSLPQEFTKYLDTSYIPRDQLINYYQSLFTGYTVEEDSVRKNDLYFRQEGVPMENTVRKILDYTHKANNSREVTELESILGELKNEYGSIISDFNRFVIILLVQAVTDSGSRSLSHANKYINDLKEDLKTIFAKIELDIETKEYIIIEAVLTFWNANPQTGFLVADAFKYAGLLTSRTIFTFIFN-ETGLKNNGLIEATAIEAVFRNLSQQISEENESGNNFEFVFERLCTIANSTIDLLDVNA---------DEDIEIPKVNGEMDIDDIEDDKLDLKWKYFTVIGFIKSILRRYS---------------------HEYRELADKFIANIDNAIPHESTRRTISNWIQETKEV--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** :* . . * : . : :.:: : *. :.*.::: * .: : :. :* * . *:* : : *. ::*::* * .::: :.. ::: * :: :***: * .:: ::: :.:.: : :* . ::: * .:*:: :::::: : . *::: .... *: :..: *: * : : .:::* :. : *: * *:. * . .:* .:. : : : * :::: .. : : : :::: : :::: :** * *::: * .: :: :*.::. :*::*: : ::*:::*: .* ::. *:.:* .::: ::*::. *:::*** ::***:* *.*::*.. : *: :* :::::* :**: ...: : :* :: . : : :.* :* : *.. .. .. *:.: . ** : * ::**:: . .::*:**: : .::. :::: : : ::. :: .* : * :: * : :: . :: .:**. * . . * :. .::::.::: : : . .: : : : . .. * . . : : ::: ::: : ::..* * :: : : ::* : ::: ::: .::. : . * :*: : ", "identical_positions": 90, "similar_positions": 316, "identity": "10.04%" }, { "cls_id": "homologset.agr.SGD:S000004734", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5SVQ0-1", "uniprot_id": "KAT7_MOUSE", "id": "Q5SVQ0-1", "name": "Histone acetyltransferase KAT7", "aln": "MAIGVVKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVRNLPSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTADHDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKVRAQSRDKQIEERMLSHRQDDNNRHATRHQAPTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKH-PPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHN---FQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q810T5-1", "uniprot_id": "KAT7_RAT", "id": "Q810T5-1", "name": "Histone acetyltransferase KAT7", "aln": "MAIG-VKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVRNLPSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQAVDFSDRETKNTADHDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKVRAQSRDKQIEERMLSHRQDDNNRHATRHQAPTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKH-PPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHN---FQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D1P2-1", "uniprot_id": "KAT8_MOUSE", "id": "Q9D1P2-1", "name": "Histone acetyltransferase KAT8", "aln": "MAAQGATAAVAATTSGTVG---EGEPGPGENAAVEGPARSPGRVS------------------------------------------PPTPAR----------GEPEVTVEIG----------ETYLCRRPD----STWHSAEVIQSRVNDQE-------------------GREEFYVHY--------VGFN------------------------------------------RRLDEWVD-KNRLALTKTVKDAVQKNSEKYLSELAEQPERKITRNQKRKHDEINHVQ-----------KTYAEMDPTTAALEKEHEAITKVKYVDKIHIGN----------YEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKFEKSYRFHLGQCQWRQ-PPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRD---FRG-TLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHL-KSAQYKKPPITVDSVCLKWAPPKHKQVKLSKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H7Z6-1", "uniprot_id": "KAT8_HUMAN", "id": "Q9H7Z6-1", "name": "Histone acetyltransferase KAT8", "aln": "MAAQGAAAAVAAGTSGVAG---EGEPGPGENAAAEGTAPSPGRVS------------------------------------------PPTPAR----------GEPEVTVEIG----------ETYLCRRPD----STWHSAEVIQSRVNDQE-------------------GREEFYVHY--------VGFN------------------------------------------RRLDEWVD-KNRLALTKTVKDAVQKNSEKYLSELAEQPERKITRNQKRKHDEINHVQ-----------KTYAEMDPTTAALEKEHEAITKVKYVDKIHIGN----------YEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQ-PPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRD---FRG-TLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHL-KSAQYKKPPITVDSVCLKWAPPKHKQVKLSKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40963-1", "uniprot_id": "SAS2_YEAST", "id": "P40963-1", "name": "Histone acetyltransferase SAS2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARSLSQSLTATTQKLKGKKNGGKGKNKPSAKIKKTQKEMLYGILNER---------------NIRQIQFGLNKKFSTWYGSAVYFDPETKRLG--------CSETKGQLSSVSNSQYWLDTLFVCEYCFKYTDDQTRFVGHVASCPFQYRVPGKIKYKSPEYTIRRVKGSKYQLFCQCLCLFTKLYLDNKSMYFKVDHYEFYIVYETG--STKPMGFFSKDLVSYQQNNLACILIFPPYQRRGLGLLLIEFSYKLSQLEGVISGPEVPLSPFGLIGYLKYWSQILCWHLIEGDLAHYDKVTLEDLSIVTGMRVNDVILTLKHLNCIGENNQIYLQS-----LNSWLKLHGTKRNWFKLKDEYLLIDD------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q00972-1", "uniprot_id": "BCKD_RAT", "id": "Q00972-1", "name": "Branched-chain alpha-ketoacid dehydrogenase kinase", "aln": "-----MILTSVLGSGPRSGSSLWPLLGSSLSLRVRSTS-----------------------------------------------------------------ATDTHHVELAR-------------ERSKTVTSFYNQSAIDVVAEKP-----------------------------------------------------------------------------------------SVRLTPTMMLYSGRSQDGSHLLKSGRYLQQELPVRIAHRIKGFRSLPFIIGCNP---------------TILHVHELYIRAFQKLTDFPPIKDQADEAQY--------CQLVRQLLDDHKDVVTLLAEG--LRESRKHIEDEKLVRYFLDKTLTSR--LGIRMLATHHLALHEDKPDFVGIICTRLSPKK---IIEKWVDFARR------LCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVITIAN--NDVDLIIRISDRGGGIAHKDLDR-VMDYHFTTAEASTQDPRISPLFGHLDMHSGGQSGPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREESFRI-", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : : : : . . . . : . . *: . :. .: . * . :: . . . : * *. : .* : : : * . : .: :. :* :.. : . :: : . .. : . : : : : : . : :: : . . : . * ", "identical_positions": 8, "similar_positions": 68, "identity": "1.28%" }, { "cls_id": "homologset.agr.SGD:S000004735", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LZ73-1", "uniprot_id": "A0ABK0LZ73_RAT", "id": "A0ABK0LZ73-1", "name": "", "aln": "-------------------MFGQGRRVGGLKRGRRRSTRPASAPGRTAWARRRPAPPCSPAPPRARSPASARSPRGPPPSATLELIVTTLLHTVEPVGLAKALSWSGPVPFKRLKNRRADKDVLKGVDASNALVLPGRKKKKTKAPPPSKKERKPLTKKERKVLQKVLEQKEKKSQRAELLQKLSEVQVSEAEMSLFYTTAKLGTG--DRMYHIKERK--PDQPAAQGQE----------------------------------------------------------------------KVSSLSGAHR------KRHRSSSTEEDSEASEDSEP---EEVTADQPRTSTGADLVHPPPATSEIKSPVPTPQPPPPGTSAPPET--------------------------------------------PASAPPP-ALAKPAVFIPVNRTPEMQEERLKLPILAEEQAIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGYSSEDS-----IIGVTEPRRVAAVAMSQRVAKEMNLSHRVVSYQIRYEGNVTEETRIKFMTDGVLLKEIQKDFLLLKYKVVIIDEAHERSVYTDILLGLLSRIVALRAKRHLP-------LKLLIMSATLRVEDFTQNQRLFTTPPPVIKVESRQFPVTVHFNKRTPLDDYSGECFRKVCKIHRMLPAGGILVFLTGQAEVHALCRRLRKAFPIRCSQPQEMEED---SAEGMR------------------RFKKSRTRARKAQA-----MALPQINLDNYSVLPAG-EGDEDREAEMDDEEEALGSDLDLDLGDS-EANEGEQPDASLPLHVLPLYSLLAPEKQAQVFKPPPEGTRLCVIATNVAETSLTIPGIKYVVDCGKVKKRYYDRVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGD-FEQFPPPEITRRPVEDLILQMKALNIEKVINFPFPTPPSVEALIAAEELLIALGALQAPPKQERMKKLQMSQLSCPITALGRTMSTFPVAPRYAKMLALSQQHGCLPYTIAIVAAMTVRELFEELDRPAASEEELAELKGRRTRVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYAGCS---PQFCQANGLRYKAMLEIRRLRGQLTTAVNAVCPEAGLFLDPKMQPPTESQVTYLRQIMAAGLGDHLARRVQSEDLLDP----KWKNAYKTPLLDDPVFIHPSSVLFRELPEFVVYQEIVET-----TKMYMKGVSTVEIQWIPSLLPSYCQFDAPLEEPAPTYCPESGRVLCHRASVFYRVGWPLPAVQVDFPEGIDRYKYFARFLLEGQVFRKLASFKSCLLSSPNTMLKTWARLQPR----TETLLRALVAQKADSRDSLLAAWKKNPKYLLAEYCEWLPKAMHGDVEKNWPPTTDR-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IY37-1", "uniprot_id": "DHX37_HUMAN", "id": "Q8IY37-1", "name": "Probable ATP-dependent RNA helicase DHX37", "aln": "--------------------------MGKLRRRYNIKGRQQAGPG------------------------PSKGPPEPPP----------------------------------VQLELEDKDTLKGVDASNALVLPGKKKKKTKAPPLSKKEKKPLTKKEKKVLQKILEQKEKKSQRAEMLQKLSEVQASEAEMRLFYTTSKLGTG--NRMYHTKEK---ADEVVAPGQE----------------------------------------------------------------------KISSLSGAHR------KRRRWPSAEEEEEEEEESESELEEESELDEDPAAEPAEAGVGTTVAPLPPAPAPSSQPVPAGMTVPPPP--------------------------------------------AAAPPLPRALAKPAVFIPVNRSPEMQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFSSEDS-----IIGVTEPRRVAAVAMSQRVAKEMNLSQRVVSYQIRYEGNVTEETRIKFMTDGVLLKEIQKDFLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLP-------LKLLIMSATLRVEDFTQNPRLFAKPPPVIKVESRQFPVTVHFNKRTPLEDYSGECFRKVCKIHRMLPAGGILVFLTGQAEVHALCRRLRKAFPPSRARPQEKDDDQKDSVEEMR------------------KFKKSRARAKKARA-----EVLPQINLDHYSVLPAG-EGDEDREAEVDEEEGALDSDLDLDLGDG-GQDGGEQPDASLPLHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDRVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGD-FEQFPPPEITRRPVEDLILQMKALNVEKVINFPFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSCPITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELFEELDRPAASDEELTRLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYASCT---PQFCEANGLRYKAMMEIRRLRGQLTTAVNAVCPEAELFVDPKMQPPTESQVTYLRQIVTAGLGDHLARRVQSEEMLED----KWRNAYKTPLLDDPVFIHPSSVLFKELPEFVVYQEIVET-----TKMYMKGVSSVEVQWIPALLPSYCQFDKPLEEPAPTYCPERGRVLCHRASVFYRVGWPLPAIEVDFPEGIDRYKHFARFLLEGQVFRKLASYRSCLLSSPGTMLKTWARLQPR----TESLLRALVAEKADCHEALLAAWKKNPKYLLAEYCEWLPQAMHPDIEKAWPPTTVH-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TYU1-1", "uniprot_id": "A0AB32TYU1_DANRE", "id": "A0AB32TYU1-1", "name": "RNA helicase", "aln": "MNVSQAADLETLTLLQISVFGCEELAMGRLRKKHNWKGRQQSTSVQ-----------------------TAAADR-QTN----------------------------------VQVEIQDGAVLKGVDDCNALVLPATKTKKQKVERPVTK-KKALTKKQRKNLEKVLEQKDKKAHRAEVLSKLAEVQLPEAELKLLYTTAKLGTG--GKLYHIKESVN-EGQDGGSSSV----------------------------------------------------------------------KISSLSGANR------KRRREADEEEEENESEMSESSEDDDDSEESDSSEEEKEKISEEKHTEEQQQQQVLKEETKPKEADMKEE--------------------------------------------KKAETWTKEDCKPAVFIPVERLPEIQEARLRLPVLAEEQIIMEAVKDHECVVLCGETGSGKTTQVPQFLYEAGFASSGG-----IIGVTEPRRVAAISMSHRVATEMNLSSGVVSYQIRYEGNVTENTKIKVMTDGVLLKEIQRDFLLQKYSVIIIDEAHERSVYTDILIGLLSRIVPLRNKKGLP-------MKLIIMSATLRVEDFTENKRLFSSPPPVIKVEARQFAVTVHFNKRTPMDDYTGETFRKICKIHRMLPPGGILVFLTGQAEVHSVCRRLRKAFP---YKPNREHTDMMETEEDLK------------------KSKR-----AKKKN-----VSLPRINLDNYSALPVD-EGDEDRQAGID-EDDGEGSDLELELGDHPDTDHEEKADPSIPLYVLPLYSLLAPEQQAKVFRPPPAGSRLCVVATNVAETSLTIPGIKYVVDCGRVKKRFYDRVTGVSSFKVTWISQASANQRAGRAGRTEPGHCYRLYSSAVFGD-FSLFSEAEITRRPVEDLVLQMKDLNIEKVVNFPFPTPPSSEALIAAEELLISLGALEKPARHGRLSEMEKARLSCPISPLGRAMAAFPVAPRYAKMLALGRQQGCMQYIITIVSAMTVREIFEDYDRPAGSEEENVKMSGKKARSVQMRRLWAGQGASLLLGDLMVLLGAVGACEFAGLT---PQFCEENGLRFKAMLEIRRLRGQLTNAVNAVCADADVYVDNKMAPPTEAQVLCLRQIVLAGLGDHIARRVQAEELLDP----KWRNAYKTPLLDDPVFIHPSSALHKTLPEFVVYQEIMET-----TKMYMRGVCAVQDDWIPKLLPQYCHFSAPEESPAPRFCPLIGRVKCHQQSTFFRVSWKLPAIEMDYPEGLERYKLFAKFFLEGQVCPKIQKFSSCLLSSPSTMLKTWAKLQPR----TEVLLTALVSEKADNRTSLEAAWRKNEKYLLSAYCQWIPESLHEEVSKIWPPIGQADPR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O46072-1", "uniprot_id": "KZ_DROME", "id": "O46072-1", "name": "Probable ATP-dependent RNA helicase kurz", "aln": "--------------------------MG--KKVHNAKARQNPQTIVD----------------------NSAVKKIQID------------------------------------VDAVAGGNQVGYDEANALVLPSEK-RATKIKVDKVQHVKILSKKQRKHLQAIVDKKKKKEGRAQLLGDLAAVQIPEEELQQYTSISQVQTVGLKRLPTLDEYLAKKKERQAQVLA----------------------------------------------------------------------EKSSASGLRVNAIKGSKRKLLVEEEEELQAKRKNPNVISVEEDDEDSSSSDEDDEEAPAQSAPIAIPTPVSIAPPQIAVKPPIKK--------------------------------------------LKPEPNPPACIHQTVYVPVHRTTEVQNARLRLPILAEEQQVMETINENPIVIVAGETGSGKTTQLPQFLYEAGYAQHK------MIGVTEPRRVAAIAMSKRVAHEMNLPESEVSYLIRFEGNVTPATRIKFMTDGVLLKEIETDFLLSKYSVIILDEAHERSVYTDILVGLLSRIVPLRHKRGQP-------LKLIIMSATLRVSDFTENTRLFKIPPPLLKVEARQFPVTIHFQKRTP-DDYVAEAYRKTLKIHNKLPEGGILIFVTGQQEVNQLVRKLRRTFPYHHAPTKDVAKNGKVSEEEKEETIDDAASTVEDPKELEFDMKRVIRNIRKSKKKFLAQMALPKINLDDYKLPGDDTEADMHEQPDEDDEQEGLEEDNDDELGLE--DESGMGSGQRQPLWVLPLYSLLSSEKQNRIFLPVPDGCRLCVVSTNVAETSLTIPHIKYVVDCGRQKTRLYDKLTGVSAFVVTYTSKASADQRAGRAGRISAGHCYRLYSSAVYNDCFEDFSQPDIQKKPVEDLMLQMRCMGIDRVVHFPFPSPPDQVQLQAAERRLIVLGALE-------VAKTENTDLPPAVTRLGHVISRFPVAPRFGKMLALSHQQNLLPYTVCLVAALSVQEVLIETG--VQRDEDVAPGAN---RFHRKRQSWAASGNYQLLGDPMVLLRAVGAAEYAGSQGRLPEFCAANGLRQKAMSEVRKLRVQLTNEINLNVSDVELGVDPELKPPTDAQARFLRQILLAGMGDRVARKVPLADIADKEERRRLKYAYNCADMEEPAFLHVSSVLRQKAPEWVIYQEAYELQNGDSTKMFIRGITAIEPEWLLLYVPLLCNIREVREDPAPRFDKTSGKIFCHVDATFGKSGWELPLGEVEMPLSEKACCYFGMFLLDGEVCSRLADFRSKLKSTPASVIKSWSSMNNK----VLRFKRALITKQIHNRQALIDQWNSDPHFLLEEYQNLLYDVALSELTPLWPPVDKKEPQRQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04217-1", "uniprot_id": "DHR1_YEAST", "id": "Q04217-1", "name": "Probable ATP-dependent RNA helicase DHR1", "aln": "--------------------------MGTYRKRFNEKARSGHMAKLKELKRIRN---------KQFTRQDENDERVENPDS--------------------------------APAESSTTEPNANAEILEPLTEEEKKMKKRKLQELFTPKESKVSRLKKKRLDKFIEHQLKREERKTIIGKLQDYKIDTS---LLTSSKRLGEGRQTKKEEFKEALSLERQGRGNEQTNEILYEEYEPKVWDEYGEGGSSEDDDGEDDFEASFGSMPKPTDNEEKKSSGFIDHRPAKFGGSGLSFGFSNIKVINKESKTPKKKYNWRQRVEMEELKKHGKEDEMDFDTTSEDDDEEEDQEEEDKMHPSENPLEEVESADSETGSEKFDQNDVANEFKDWANQEIKKLEGRDQELVTPTLNIDYKPIIRKEDLDDGLQEAYVPINENSTRKAFYVEVSRSDEIQKARIQLPVFGEEHKIMEAIHHNDVVIICGETGSGKTTQVPQFLYEAGFGAEDSPDYPGMVGITQPRRVAAVSMAERVANELGDHGHKVGYQIRFDSTAKEDTKVKFMTDGVLLREMMHDFKLTKYSSIIIDEAHERNINTDILIGMLSRCVRLRAKLHKENPIEHKKLKLIIMSATLRVSDFSENKTLFPIAPPVLQVDARQFPVSIHFNRRTA-FNYTDEAFRKTCKIHQKLPPGAILVFLTGQQEITHMVKRLRKEFPFKKNSKYNKDLETPVSKMGIN---------------------------SKTTD-------LEAEDIDFSVQVIDQDKFKSAIRYEEDEGNSGNGEDEEDEEEEGFEEVLTEGQTANDPLYVLPLYSLLPTKEQMRVFQKPPQGSRLCIVATNVAETSLTIPGVRYVVDSGRSKERKYNESNGVQSFEVGWVSKASANQRSGRAGRTGPGHCYRLYSSAVFEHDFEQFSKPEILRMPVESIVLQMKSMAIHNIINFPFPTPPDRVALSKAIQLLQYLGALDN---------------KEMITEDGKKMSLFPLSPRFSKMLLVSDEKACLPYIVAIVSALSVGDPFINEFELGINEISRKPNPDENLDDKIREHDESTPGMDPELKKELRSKFYKSRSQFSKLD---------KFSDVFRLLSVVSAMDYVPKEQKEIFMKKNFLRGKLMEEIVKLRKQLMYIIKSNTSKENIAVVIRNEDLKSD----------------------IPSVIQIKLLKQMICAGFVDH-------VAVRADVLFPDDAKITNRTSIINIPYIPVLATRTPNIEDCFVYIHPTSILNNLGEMPPKYMLYYSLHLGGNNKTRMNTLCDIASTPLANIARKGLLLTYSKPLTGQGLKTVNLSPTERYCYVVPRFGSTVDNDLKIGWDLNPIAVHQKKQKGQWTVIKFITRKGFQTITGEEKEKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :: . . * . . : :.*. * : * . ::: ::* *: .:::: *: * :: .* : : :: : .* : . : . . : : . ** : . . :. : . : :.:: * * *:*: *::**::.**: :**:: .: *::.**********:********:. ::*:*:******::*:.*** *:. *.* **::.... *::*.*******:*: ** * :*. :*:******.: ****:*:*** * ** * :**:********.**::* ** .**:::*::***.*::**::**. :* * :** ***. ** *.**:*:*** *: : ::**: ** : : . * * ::* : . . * : . .* : : ** ********..::* ::* * * ***:::*********** ::****.*: * * *:. .**.:* * : *:***:**:***** .***********: . *. *. .:* : ***.::***: : :..:::****:**. * * . * ****: :: *: :: **::**:.*** :. :: : * : :*::::* : : : : . . .: : * * . : . .::: : : .: :.. : . . . : .. : : * :.:* : :: . .*.: : :: : : ::. . : . :: .: : * : : . . * : . * . . : . . : : :: . .: * * : : : : . ", "identical_positions": 250, "similar_positions": 290, "identity": "17.54%" }, { "cls_id": "homologset.agr.SGD:S000004737", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CYW4-1", "uniprot_id": "HDHD3_MOUSE", "id": "Q9CYW4-1", "name": "Haloacid dehalogenase-like hydrolase domain-containing protein 3", "aln": "--------------MAHRLQMRLLTWDVKDTLIKLRRPVGEEYASKARAHGVV-VEDITVEQAFRQAYRAQSHNFPNYGLSR--GLTSRQWWKDVVLHTFRLAG-VPDAQAMTPVADQLYEDFSSPFTWQVLEGAEMTLKGCRKRGLK----LAVVSNFDRRLEDILTGLGLREHFD-FVLTSEAVGCPKPDPRIFREALQR-------------ACVEPAVAAHVGDSYLCDYQGSQAVGMHSFLVAGSEPLDSAVR----------------DSVPKEHILPSLSHLLPALDLLEASSPMS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BSH5-1", "uniprot_id": "HDHD3_HUMAN", "id": "Q9BSH5-1", "name": "Haloacid dehalogenase-like hydrolase domain-containing protein 3", "aln": "--------------MAHRLQIRLLTWDVKDTLLRLRHPLGEAYATKARAHGLE-VEPSALEQGFRQAYRAQSHSFPNYGLSH--GLTSRQWWLDVVLQTFHLAG-VQDAQAVAPIAEQLYKDFSHPCTWQVLDGAEDTLRECRTRGLR----LAVISNFDRRLEGILGGLGLREHFD-FVLTSEAAGWPKPDPRIFQEALRL-------------AHMEPVVAAHVGDNYLCDYQGPRAVGMHSFLVVGPQALDPVVR----------------DSVPKEHILPSLAHLLPALDCLEGSTPGL----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T012-1", "uniprot_id": "HDHD3_DANRE", "id": "Q7T012-1", "name": "Haloacid dehalogenase-like hydrolase domain-containing protein 3", "aln": "----------------MRVPVRWVLWDVKDTLLKVRRSVGEQYCREAQQAGLQ-LSPAQVETAFRLAYKQKSQLLPNYGRAQ--GMDSQVWWTGLVRDTFGQCG-VHDPALLDKLANNLYHNFCGPENWEVFSDSNSTLKSCTALGLK----QGVVSNFDRRLEGILRGCGLLTHFS-FIVTSEDARVAKPDPAIFSQALER-------------CGVPASSVVHVGDHYVKDYLTSRSLGIRGYLLNRKD--GQKTH----------------LDIPPEHILQSLDELPARLQHNTD---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94915-1", "uniprot_id": "REG2_DROME", "id": "Q94915-1", "name": "Rhythmically expressed gene 2 protein", "aln": "--------------MRSLSRFRLITFDVTNTLLQFRTTPGKQYGEIGALFGAR-CDNNELAKNFKANWYKMNRDYPNFGRDTNPQMEWQQWWRKLIAGTFAESGAAIPDEKLHNFSNHLIELYKTSICWQPCNGSVELLQQLRKELKPEKCKLGVIANFDPRLPTLLQNTKLDQYLD-FAINSYEVQAEKPDPQIFQKAMEKSG----------LKNLKPEECLHIGDGPTTDYLAAKELGWHSALVHEKSYAYLVKKYG--------------EDIDRDHVFPSLYDFHKKISDGAVVW-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W4J7-1", "uniprot_id": "Q9W4J7_DROME", "id": "Q9W4J7-1", "name": "", "aln": "-------MSLTSQFVANLKRFRLVTFDVTDTLLRLED-PLRQYHQTAEEFGVTGVDRRRLEQCFRQQFKAMSSEHPNFGRYS-PGLDWQRWWLQLVARTFSCVDHGLAPEKLEKIGQRLISVFRTSACWSHVNGAQELVQNVRNAGK----CVGIISNFDSSLPQVLDAMGFAGKFD-FILTSYEAGVMKPERGIFEIPLQR-------------LQIPAEQALHIGNKLDMDYEGARNCGWSGLLVSN---------------------------ADNPHSFASLSSLLEALKTQPIRW-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04223-1", "uniprot_id": "YM14_YEAST", "id": "Q04223-1", "name": "Uncharacterized protein YMR130W", "aln": "MTYPKRIPINAWSEVHRVARPLIITFDAYNTLYATKLPVMEQYCIVGRKYGIK-ANPSTLTNNFPHVFKKLKEDYPQYGKYS--GIKPEQWWSILIRNVF------APNEIPDEMINEILMRFEGFDSYFVYPDLIKFLKDLKSRHPD--VILGIVSNTDPIFYKLLKNIGLFETFSGHIYLSYELNLAKPDRAIFQYALDDIISKQPHLLEKYTREEILQHCFHIGDELKNDLEGAEAAGWTGILLDRNDKYGFLSNSISKPMRDEYKLSIDKIDNNSINTWEANTKQTDTLQLSERKYVVSNLEVLEELFP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*. :** . . * . * . : * : . *::* : . ** :: .* . :.: : : . :: .:::* * : :* : :. . * **: ** .: *:*: * .. * . *: : : :. ", "identical_positions": 24, "similar_positions": 50, "identity": "7.67%" }, { "cls_id": "homologset.agr.SGD:S000004738", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI13-1", "uniprot_id": "GRWD1_RAT", "id": "Q5XI13-1", "name": "Glutamate-rich WD repeat-containing protein 1", "aln": "---------------------------------MAARKG-------------------------------RRHTCETGEPMEAETYDLGSEGPSQVYLPGRGPPLGEGEELVMDEEAYVLYHRAQTGAPCLSFDIVRDHLGDNRTELPLSLYLCAGTQAESAQSNRLMMLRMHNLHGTRPPPSEGSDD-EDDEDEEDEEERKPQLELAMVPHYGGINRVRVS---WLGEEPVAGVWSEKGQVEVFALRRLLQVVDDPQALAIFLRDEQARVKPIFSFAGHMG-EGFALDWSPRVP-GRLLTGDCQKNIHLWTPTDGGSWNVDQRPF-VGHTRSVEDLQWSPTEDTVFASCSADASIRIWDIRAAPGKACMLTTAAAHDGDVNVISWSRREPFLLSGGDD-GTLKVWDLRQFKSG-----SPVATFKQHVAPVTSVEWHPQDSGVFAASGADNQITQWDLAVERDPE--SGETETDPGLAALPQQLLFVHQGETDLKELHWHPQCPGVLISTALSGFTVFRTISV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q810D6-1", "uniprot_id": "GRWD1_MOUSE", "id": "Q810D6-1", "name": "Glutamate-rich WD repeat-containing protein 1", "aln": "---------------------------------MAARKG-------------------------------RSRTCETGEPMEAETCDPGTEGPSQVYLPGRGPPLSEGEELVMDEEAYVLYHRAQTGAPCLSFDIVRDHLGDNRTELPLSLYLCAGTQAESAQSNRLMMLRMHNLHGTRPSPSEGSDDDEEDEDEEDEEEQKPQLELAMVPHYGGINRVRVS---WLGEEPVAGVWSEKGQVEVFALRRLLQVVDDPQALAIFLRDEQARIKPIFSFAGHMG-EGFALDWSPRVP-GRLLTGDCQKNVHLWTPTEGGSWNVDQRPF-VGHTRSVEDLQWSPTEDTVFASCSADASIRIWDIRAAPGKACMLTTATAHDGDVNVISWSRREPFLLSGGDD-GALKVWDLRQFKSG-----SPVATFKQHMAPVTSVEWHPQDSGVFAASGADNQITQWDLAVERDPE--SGETETDPGLAALPQQLLFVHQGETDLKELHWHPQCPGVLISTALSGFTVFRTISV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQ67-1", "uniprot_id": "GRWD1_HUMAN", "id": "Q9BQ67-1", "name": "Glutamate-rich WD repeat-containing protein 1", "aln": "---------------------------------MAARKG-------------------------------RRRTCETGEPMEAESGDTSSEGPAQVYLPGRGPPLREGEELVMDEEAYVLYHRAQTGAPCLSFDIVRDHLGDNRTELPLTLYLCAGTQAESAQSNRLMMLRMHNLHGTKPPPSEGSDEEEEEEDEEDEEERKPQLELAMVPHYGGINRVRVS---WLGEEPVAGVWSEKGQVEVFALRRLLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMG-EGFALDWSPRVT-GRLLTGDCQKNIHLWTPTDGGSWHVDQRPF-VGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGGDD-GALKIWDLRQFKSG-----SPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQWDLAVERDPE--AGDVEADPGLADLPQQLLFVHQGETELKELHWHPQCPGLLVSTALSGFTIFRTISV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04225-1", "uniprot_id": "RRB1_YEAST", "id": "Q04225-1", "name": "Ribosome assembly protein RRB1", "aln": "MSKRSIEVNEEQDRVVSAKTESHSVPAIPASEEQDAPKNDLEEQLSDEFDSDGEIIEIDGDDEINDEDDLRKKQEEAETLVQKDQSEGNKEKIQELYLPHMSRPLGPDEVLEADPTVYEMLHNVNMPWPCLTLDVIPDTLGSERRNYPQSILLTTATQSSRKKENELMVLALSNLAKTLLK----DDNEGEDDEEDDEDDVDPVIENENIPLRDTTNRLKVSPFAISNQEVLTATMSENGDVYIYNLAPQSKAFSTPG-----YQIPKSAKRPIHTVKNHGNVEGYGLDWSPLIKTGALLSGDCSGQIY-FTQRHTSRWVTDKQPFTVSNNKSIEDIQWSRTESTVFATAGCDGYIRIWDTRSKKHKPAISVKASNTD--VNVISWSDKIGYLLASGDDNGTWGVWDLRQFTPSNADAVQPVAQYDFHKGAITSIAFNPLDESIVAVGSEDNTVTLWDLSVEADDEEIKQQAAETKELQEIPPQLLFVHW-QKEVKDVKWHKQIPGCLVSTGTDGLNVWKTISV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *. * : *: :: : : ..* ::*** . ** .* * * .* : *..: ***::*:: * **.:* : * :: * :.**:. :.*.**:* : ** * .*: ::::*:**:: .* :* :* . **::** .:* ::.. **:*:* :: * :... * : :: :**.:. .* . **:.***** : * **:***. ::: :* . . * .*::** *.:.:*:**:*** **.****:...*. ***** *: *..: ..*: * ******* : :**:.*** *: :******... .*** :. * ..:**: ::* *..:.*... *: :* ***:** * * :. * :* ****** :.::*:::** * ** *:**. .*:.:::****", "identical_positions": 155, "similar_positions": 153, "identity": "29.58%" }, { "cls_id": "homologset.agr.SGD:S000004739", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAU6-1", "uniprot_id": "D4AAU6_RAT", "id": "D4AAU6-1", "name": "Coiled-coil domain-containing protein 25", "aln": "MVFYFTSS-SVNSSTYTIYMGKDKYENEDLIKYGWPED--VWFHVDKLSSAHVYLRLQKGE-KIEDIPKEVLMDCAHLVKANSIQGCKMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIVTVEKKVNEILNRLEKTK-LEKFPDLAAEKEGRDREERNEKKAQIQEMKRKEKEEMKKKREMDELRSYSSLMKVENMSSNQD-GNDSDEFM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q78PG9-1", "uniprot_id": "CCD25_MOUSE", "id": "Q78PG9-1", "name": "Coiled-coil domain-containing protein 25", "aln": "MVFYFTSS-SVNSSTYTIYMGKDKYENEDLIKYGWPED--IWFHVDKLSSAHVYLRLQKGE-KIEDIPKEVLMDCAHLVKANSIQGCKMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIVTVEKKVNEILNRLEKTK-LEKFPDLAAEKEGRDREERNEKKAQIQEMKRKEKEEMKKKREMDELRSYSSLMKVENMSSNQD-GNDSDEFM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86WR0-1", "uniprot_id": "CCD25_HUMAN", "id": "Q86WR0-1", "name": "Coiled-coil domain-containing protein 25", "aln": "MVFYFTSS-SVNSSAYTIYMGKDKYENEDLIKHGWPED--IWFHVDKLSSAHVYLRLHKGE-NIEDIPKEVLMDCAHLVKANSIQGCKMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIVTVEKKVNEILNRLEKTK-VERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDELRSYSSLMKVENMSSNQD-GNDSDEFM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T312-1", "uniprot_id": "CCD25_DANRE", "id": "Q7T312-1", "name": "Coiled-coil domain-containing protein 25", "aln": "MVFYFTS--AVVSPPHTIYMGKDKYENEDLIKYGWPED--IWFHVDKLSSAHVYLRMPKGT-TIDDIPKEVLIDCVQLVKNNSIQGCKMNNINIVYTPWSNLKKTADMDIGQIGFHRQKEVKIVAVEKKINEIVNRLEKTK-EERYPDLAAEKESRDREERNEKKAQIQEQKKKEKEEVKKKKEMEDLKNYTSLMKSDNMTTNED-GYDSDDFM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3T2-1", "uniprot_id": "Q9W3T2_DROME", "id": "Q9W3T2-1", "name": "Coiled-coil domain-containing protein 25", "aln": "MVFYFKS--NVVQPPAMLYMGRDKHENEELIRWGWPED--VWFHVHDLSSAHVYLRLRKGQ-TIDDIPTDVLVDAAQLCKANSIQGNKVNNLEVVYTMWENLKKTPDMEPGQVAYHNEKAVRRIRLEKRINEIVNRLNRTKTEEEHPDFRGLREARDAAERQDQKKIQRERREQEKEAAKQRELEAELRSYASLQKSENMRTNYDAGNESDDFM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40206-1", "uniprot_id": "JLP2_YEAST", "id": "P40206-1", "name": "Protein JLP2", "aln": "MVYFYESKPTEYSTPYQIVMGKDKFENDLLIKWSYRELNYVWFHADKYSSGHVYLKLRPNEKTIDDIPQEVICDCLQLCKSESIQGNKMPQCTILITPWHNLRKNRYMNPGEVSFKSLRQCRKMECGARDNKILNRLAKTR-VELFNNVEATLNEAKKTKNGDFFVNYIESNRSNLIEEEKLRKVAKKN-----QKKKNKQSKDEVTDDMQLEV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::: * ... : **:**.**: **: .: * :***... **.****:: . .*:*** :*: *. :* * :**** *: : :: * * **:*. *: *::.:: : : : : *:*:*** :*: * . :. . : . :. : * .. : :: . . . * .* :: : : : :", "identical_positions": 51, "similar_positions": 72, "identity": "23.83%" }, { "cls_id": "homologset.agr.SGD:S000004742", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LGR9-1", "uniprot_id": "A0ABK0LGR9_RAT", "id": "A0ABK0LGR9-1", "name": "", "aln": "------------------------MSYAEKPDEITKDEWMEKLNNLHVQ------------------------------------RADMNRLIMNYLVTEGFKEAAEKFRMESGIEPS-------VDLETLDERIKIREMILKGQIQEAIALINSLH--------------------------PELLDTNRYLYFHLQQQHLIELIRQRE------------TEAALEFAQTQLAEQGEESRECLTEMERTLALLAFDSPEES---------PFGDLLHMMQRQKVWSEVNQAVLDYENRE----STPKLAKLLKLLLWAQNELDQKKVKYP----------KMTDLSKGVIEEPK---------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D7M1-1", "uniprot_id": "GID8_MOUSE", "id": "Q9D7M1-1", "name": "Glucose-induced degradation protein 8 homolog", "aln": "------------------------MSYAEKPDEITKDEWMEKLNNLHVQ------------------------------------RADMNRLIMNYLVTEGFKEAAEKFRMESGIEPS-------VDLETLDERIKIREMILKGQIQEAIALINSLH--------------------------PELLDTNRYLYFHLQQQHLIELIRQRE------------TEAALEFAQTQLAEQGEESRECLTEMERTLALLAFDSPEES---------PFGDLLHMMQRQKVWSEVNQAVLDYENRE----STPKLAKLLKLLLWAQNELDQKKVKYP----------KMTDLSKGVIEEPK---------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NWU2-1", "uniprot_id": "GID8_HUMAN", "id": "Q9NWU2-1", "name": "Glucose-induced degradation protein 8 homolog", "aln": "------------------------MSYAEKPDEITKDEWMEKLNNLHVQ------------------------------------RADMNRLIMNYLVTEGFKEAAEKFRMESGIEPS-------VDLETLDERIKIREMILKGQIQEAIALINSLH--------------------------PELLDTNRYLYFHLQQQHLIELIRQRE------------TEAALEFAQTQLAEQGEESRECLTEMERTLALLAFDSPEES---------PFGDLLHTMQRQKVWSEVNQAVLDYENRE----STPKLAKLLKLLLWAQNELDQKKVKYP----------KMTDLSKGVIEEPK---------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FGY2-1", "uniprot_id": "GID8B_DANRE", "id": "E7FGY2-1", "name": "Glucose-induced degradation protein 8-B homolog", "aln": "-----------------------MMSYAEKPEDITRDEWMEKLNNVHIQ------------------------------------RADMNRLIMNYLVTEGFKEAAEKFRMESGIEPS-------VDLDSLDERIKIREMVLKGQIQEAIALINSLH--------------------------PELLDTNRYLYFHLQQQHLIELIRLRE------------TEAALEFAQTQLAEQGEESRECLTEMERTLALLAFDNPEES---------PFGDLLNMMQRQKVWSEVNQAVLDYENRE----STPKLAKLLKLLLWAQNELDQKKVKYP----------KMTDLSKGTIEDPK---------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6PC55-1", "uniprot_id": "GID8A_DANRE", "id": "Q6PC55-1", "name": "Glucose-induced degradation protein 8-A homolog", "aln": "------------------------MSYSEKPEDITKEEWMDKLNNVHIQ------------------------------------RADMNRLIMNYLVTEGFKEAAEKFRMESGIEPN-------VDLDSLDERIKIREMVLKGQIQEAIALINSLH--------------------------PELLDTNRYLYFHLQQQHLIELIRLRE------------TEAALEFAQSQLAEQGEESRECLTEMERTLALLAFDNPEES---------PFGDLLNMMQRQKVWSEVNQAVLDYENRE----STPKLAKLLKLLLWAQNELDQKKVKYS----------RMTDLSKGTIEDPK---------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWS1-1", "uniprot_id": "Q9VWS1_DROME", "id": "Q9VWS1-1", "name": "", "aln": "------------------------MSYNEKSEAIIKEEWLQRLEQFPFK------------------------------------QADMNRLIMNYLVTEGFKEAAEKFQHEADLEPS-------VELSSLDGRILIREAVQAGRIEEATQLVNQLH--------------------------PELLGSDRYLFFHLQQLQLIELIRAGK------------VEEALSFAQSKLSESGE---EAMFELERTLALLAFEKPQES---------PFADLLEQSYRQKIASELNSAILRCEQSED---STPKMMFLLKLILWAQSKLDSRSISYP----------KMKNLETAHLE-PK---------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40208-1", "uniprot_id": "GID8_YEAST", "id": "P40208-1", "name": "GID complex subunit 8", "aln": "MTISTLSNETTKSGSCSGQGKNGGKDFTYGKKCFTKEEWKEQVAKYSAMGELYANKTIHYPLKIQPNSSGGSQDEGFATIQTTPIEPTLPRLLLNYFVSMAYEDSSIRMAKELGFIRNNKDIAVFNDLYKIKERFHIKHLIKLGRINEAMEEINSIFGLEVLEETFNATGSYTGRTDRQQQQQQQQFDIDGDLHFKLLLLNLIEMIRSHHQQENITKDSNDFILNLIQYSQNKLAIKASSSVKKMQELELAMTLLLFPLSDSADSGSIKLPKSLQNLYSISLRSKIADLVNEKLLKFIHPRIQFEISNNNSKFPDLLNSDKKIITQNFTVYNNNLVNGSNGTKITHISSDQPINEKMSSNEVTAAANSVWLNQRDGNVGTGSAATTFHNLENKNYWNQTSELLSSSNGKEKGLEFNNYYSSEFPYEPRLTQIMKLWCWCENQLHHNQIGVPRVEN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . : ::** ::: : .. : **::**:*: .::::: :: * .: . :* .:. *: *:. : *:*:** :*.:. : :. : *.*:* :***:** . :.::*.:*: ... : : *:* :::** * .:.: .: :* *.*: . :*. :* : . : : : .*: :. : .. * ::..:.. * ", "identical_positions": 39, "similar_positions": 99, "identity": "8.57%" }, { "cls_id": "homologset.agr.SGD:S000004745", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z924-1", "uniprot_id": "D3Z924_RAT", "id": "D3Z924-1", "name": "DNA cross-link repair 1A protein", "aln": "MLEDAFWEEDIWEYKSKRKPKPVHPNSCSENISESVEKATDGKYQSKGKGNKKRTSENPGETKDHPVCLAETNSQISAGSSQNSSCRDDIQQSQSKETTPKKQCRTNRGKQATPKVRPLYDGHCPSCQMPFSSLLGQTPRWHVFECLDSPPISDTECPDGVLCSSTIPSHYKKYTHVLLAQSRDSKEPLS-PSQALAGRFAAAQPDS-CNLEERRSVLLKTEDSRKVLEDSLLMIQCLKTSQPPAETNRKSASSPRSQKSLVPQRAEFVKRDQLVGSGSPLAEVAFNCQSESGSTGLPLPENGCGDFEISYSPLHSDEETYNCDQELDDSQQELFFTQSSKDSSL---EDVSATFENLHGPFPEEAEGIQPTAKTLAAQAGCSA-LSRGSTGNDSFQLISRTSGRLSGEDPSDTDAAFLLLSPAPSAVGGATPNCQTTKAK---PEKFHSLASRHQQQKTETSAAGSHTSLPLLLSAMSKPLEKEGGERLPLHPTQSQRRGLWSKGSGAPG---ANCACS--------------NTQRPSSAPLNKSLSTAPSSPKGSASQPSKKVMKQMDIGVFFGLPPKTQDTSPR-ERASEGPKASPVVSPSEKRPRLCKRKAQSSLSDLEFDAKNLNESQHSMELSGERAQHRRKRHKKSNSPQEGTYQGRSGHLTNNPELGAVSLRRSKAFARRTPSRTQRGAVNISESSGGGESRR-TCPFYKRIPGTGFTVDAFQYGEIEGCTAYFLTHFHSDHYAGLSKDFTRPIYCSEITGSLLKKKLRVQEQYIHQLPMDTECIVDGVKVVLLDANHCPGATMILFQLPNGAVTLHTGDFRADPSMERSLLASRKVHTLFLDTTYCSPEYTFPSQQEAIQFAINTAFEAVTLNPRALIVCGTYCIGKEKVFLAIADVLGSKVGMSQEKYKTLQCLNIPEVSSLITTDMCNSLVHLLPMMQINFKGLQNHLKKCGGKFDQILAFRPTGWTHSNNITSIADITPQTKGNIAIYGIPYSEHSSYLEMKRFVQWLKPQKIIPTVNVGTFQSRNTMEKYFKEWRLEAGY----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIC3-1", "uniprot_id": "DCR1A_MOUSE", "id": "Q9JIC3-1", "name": "DNA cross-link repair 1A protein", "aln": "MLEDT-WEEEIWEYKSKRKPKPVHPNNCSENISESVEKSTDGKHQSKG--NEKRTSENPGKTKDHKVCLAETDSQISAGSSQSSSCRDESQQSQNKETTPKKQHRTRRGKQVTPKVRPVYDGYCPSCQMPFSSLLGQTPQWHVFECLDSPPISDTECPEGLLCTSTIPSHYKKYTHILLAQSRDSKEPLGSPSDALAGLFAAAAPGSPCNLEERRSMTLKTENLRKVSDHSLLMMQYLETSQPSAEINRKNVSSPCSQTSPVPQCAEFVKRDQLVGGGSPLAEVALNSQSKSGSMGLPLPENDTDSCEISYSPLHSDEETYDIDQELDDSQQELFFTQSSKDSSLE--EDGSAIFENLHGPSPKEAEGIRPTAKSLVAQARCSA-PSEGSTLSDSFLLLSYTSNRLSQEDLPHTDAAFHLLSPA-LAVGGAASNYQTSKAKLDEPEKFLSLASSHQQQKIETSAVGNQTSLPLLTRARSKPLEKEGGKCLPLHPTQSQTRGSPRKGLGAPG---ANCACR--------------NAQKRSSMPLDKPLGTSPSSPKCSPSQPSKKVMKQMDIGVFFGLPPKRQETSLR-ESASEGPNVSPVVSPNQKRPRLCKRKAQSSLSDLEFDAKNLNESQHSVGLSGEKRQHRRKRHKTSNSPREGPCQRRSGHLMNNPELGPVSL--SKAFVRRTRGRTQRGNMNISESSGAGEVRR-TCPFYKRIPGTGFTVDAFQYGEIEGCTAYFLTHFHSDHYAGLSKDFTRPVYCSEITGNLLKKKLRVQEQYIRQLPMDTECVVDSVKVVLLDANHCPGATMILFQLPNGAVILHTGDFRADPSMERSRLAGRKVHTLFLDTTYCSPEYTFPSQQEVIQFAINTAFEAVTLNPRALVVCGTYCIGKEKVFLAIADVLGSKVGMSQEKYKTLQCLNIPEVSSLITTDMCDSLVHLLPMMQINFKGLQSHLKKCGGKYDQILAFRPTGWTHSNNITSTADIIPQTRGNISIYGIPYSEHSSYLEMKRFVQWLKPQKIIPTVNVGSFRSRNTMEKYFKEWRLEAGY----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PJP8-1", "uniprot_id": "DCR1A_HUMAN", "id": "Q6PJP8-1", "name": "DNA cross-link repair 1A protein", "aln": "MLEDI-SEEDIWEYKSKRKPKRVDPNNGSKNILKSVEKATDGKYQSKRSRNRKRAAEAK-EVKDHEVPLGNAGCQTSVASSQNSSCGDGIQQTQDKETTPGKLCRTQKSQHVSPKIRPVYDGYCPNCQMPFSSLIGQTPRWHVFECLDSPPRSETECPDGLLCTSTIPFHYKRYTHFLLAQSRAGDHPFSSPSPASGGSFSETKSGVLCSLEERWSSYQNQTDN-SVSNDPLLMTQYFKKSPSLTEASEK-ISTHIQTSQQALQFTDFVENDKLVG-------VALRLANNSEHINLPLPENDFSDCEISYSPLQSDEDTHDIDEKPDDSQEQLFFTESSKDGSLEEDDDSCGFFKKRHGPLLKDQDESCPKVNSFLTRDKYDEGLYRFNSLNDLSQPISQNNESTLPYDLACTGGDFVLFPPA-LAGKLAASVHQATKAKPDEPE-FHSAQSNKQKQVIEESSVYNQVSLPLVKSLMLKPFESQVEGYLSSQPTQNTIRKLSSENLNAKNNTNSACFCRKALEGVPVGKATILNTENLSSTPAPKYLKILPSGLKYNARHPSTKVMKQMDIGVYFGLPPKRKEEKLLGESALEGINLNPVPSPNQKRSSQCKRKAEKSLSDLEFDASTLHESQLSVELSSERSQRQKKRCRKSNSLQEGACQKRSDHLIN-TESEAVNLSKVKVFTKSAHGGLQRGNKKIPESSNVGGSRKKTCPFYKKIPGTGFTVDAFQYGVVEGCTAYFLTHFHSDHYAGLSKHFTFPVYCSEITGNLLKNKLHVQEQYIHPLPLDTECIVNGVKVVLLDANHCPGAVMILFYLPNGTVILHTGDFRADPSMERSLLADQKVHMLYLDTTYCSPEYTFPSQQEVIRFAINTAFEAVTLNPHALVVCGTYSIGKEKVFLAIADVLGSKVGMSQEKYKTLQCLNIPEINSLITTDMCSSLVHLLPMMQINFKGLQSHLKKCGGKYNQILAFRPTGWTHSNKFTRIADVIPQTKGNISIYGIPYSEHSSYLEMKRFVQWLKPQKIIPTVNVGTWKSRSTMEKYFREWKLEAGY----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VND2-1", "uniprot_id": "Q9VND2_DROME", "id": "Q9VND2-1", "name": "", "aln": "-------------------------------------------------------MSNVGKIKIRSIADLQATVRVNVEPDPTPTIEN--------RTPDKKRAGRTRAASTTKKVRPKTEACPIIASTAFKRSSKKTP-----------------LPGQMRIDSFFTSAVKNYKVKSSSSCRKVDPPLDKRKVSTKG---------------RKRLFEESTTTSSAFTGKLDAKPSEKRVQP----SRRAKGKENASLSEVHVIDLCSEDEQTIKRKPSAIASPCEKSSDVQATKFRTPETSMPEAKLSNSSLDLVEISPGPNKSPTNN-----------------------FYRSSPAAITKESPLGKNSKKGTVRKQRKPK-------PCPPYKVVEGTSFCVDGFQFGEIEGVTHYFLTHFHADHYIGLTKKFCHPLYVSPISARLVRTFIKLDETHIHEIDVDQTLDVDGVQVTALEANHCPGALMFFFKLSSGECILHTG----------------------------------DFRASADMESLPIFWNHSNIDLLYLDTTYMNKNYDFCHQSESVDRAVDLVRAFLEKNAAKRILIVCGSYVIGKEKIWLAL-----------AKEFTMRVWTESNRSTAVRCLNWPDLDSVLTEDRSGANLHVIAMGKISYPSLVDYFTEFEDQYD---------------------MLLGIRPSGWEKNSKPS--------------YGKRISTIGIEYSEHSSYKELER---FVRFLKPKRVISTVPVGRDLYVT-------------GEVPIRWYKYEGRASMLRTGFQPS-----------------ISTFLATPKRAFAKFSADTEMFLSPVDENASKGSEDKKDDDRESVVPTNHVTIISDTP-------EECFQTDSKIPVKNEPLAPDTSPNSEIVAQLNAMESEIPYVEIDIKNETIAPDAVLIPR----------VPTEDTFQSTDCNVIGVQKSQAVVVSRLTSDASDDWLL------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P30620-1", "uniprot_id": "PSO2_YEAST", "id": "P30620-1", "name": "DNA cross-link repair protein PSO2/SNM1", "aln": "------------------------------------------------------------MSRKSIVQIRRSEVKRKRSSTASSTSEG--------KTLHKNTHTSSKRQRTLTEFNIPTSSNLPVRSSSYSFSR-------------------FSCSTSNKNTEPVIINDDDHNSICLEDTAKVEITID----------------------------TDEEELVSLHDNEVSAIENRTEDRIVTELEEQVNVKVSTEVIQCPICLENLSHLELYER-----ETHCDTCIGSDPSNMGTPKKNIRS------------------------------------------------FISNPSSPAKTKRDIATSKKPTRVKLVLPS--------FKIIKFNNGHEIVVDGFNYKASETISQYFLSHFHSDHYIGLKKSWNNPD------ENPIKKTLYCSKITAILVNLKFKIPMDEIQILPMNKRFWITDTISVVTLDANHCP----------------------------------------------GAIIMLFQEFLANSYDKPIRQILHTGDFRSNAKMIETIQKWLAETANETIDQVYLDT------------------------------TYMTMGYNFPSQHSVCETVADFTLRLIKHGKNKTFGDSQRNLFHFQRKKTLTTHR---------------------------YRVLFLVGT--------------------------YTIGKEKLAIKICEFLKTKLFVMPNSVKFSMMLTVLQNNENQND-----------------------MWDESLLTSNLHES-------------------SVHLVPIRVLKS-QETIEAYLKSLKELETDYVKDIEDVVGFIPTG---------------------WSHNFGLKYQKKNDDDENEMSGNTEYCLELMKNDRDNDDENGFEISSILRQYKKYN----------------------KFQVFNVPYSEHSSFNDLVKFGCKLKCSEVIPTVNLNNLWKVRYMTNWFQCWENVRKTRAAK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: : . . ..: . .* : : . :.. .. . .:. . . . . :. . . .:. . . : ..: . . : : *:.. . : . .. : . : : . . : : . : . :. . . . .: : . . . : . : * .: : . : . . : .. . : * :. . . : : : . : : .:: . : * .: . . . :.. * : . :. : : .. .. * *: : : . : . :. . : * * ", "identical_positions": 10, "similar_positions": 133, "identity": "0.95%" }, { "cls_id": "homologset.agr.SGD:S000004746", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D0J4-1", "uniprot_id": "ARL2_MOUSE", "id": "Q9D0J4-1", "name": "ADP-ribosylation factor-like protein 2", "aln": "MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFNGED---VDTISPTLGFNIKTLEHRGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAG---ATLLIFANKQDLPGALS-----CNAIQEALELDSIRSHHWRIQGCSAVTGEDLLPGIDWLLDDISSRVFTAD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08697-1", "uniprot_id": "ARL2_RAT", "id": "O08697-1", "name": "ADP-ribosylation factor-like protein 2", "aln": "MGLLTILKKMKQKERDVRLLMLGLDNAGKTTILKKFNGED---VDTISPTLGFNIKTLEHRGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAG---ATLLIFANKQDLPGALS-----CNAIQEALELDSIRSHHWRIQGCSAVTGEDLLPGIDWLLDDISSRVFTAD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36404-1", "uniprot_id": "ARL2_HUMAN", "id": "P36404-1", "name": "ADP-ribosylation factor-like protein 2", "aln": "MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFNGED---IDTISPTLGFNIKTLEHRGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAG---ATLLIFANKQDLPGALS-----SNAIREVLELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDISSRIFTAD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q06849-1", "uniprot_id": "ARL2_DROME", "id": "Q06849-1", "name": "ADP-ribosylation factor-like protein 2", "aln": "MGFLTVLKKMRQKEREMRILLLGLDNAGKTTILKRFNGEP---IDTISPTLGFNIKTLEHNGYTLNMWDVGGQKSLRSYWRNYFESTDGLVWVVDSADRMRLESCGQELQVLLQEERLAG---ATLLVLCNKQDLPGALS-----SNEIKEILHLEDITTHHWLVAGVSAVTGEKLLSSMDWLIADIAKRIFTLD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39110-1", "uniprot_id": "CIN4_YEAST", "id": "P39110-1", "name": "GTP-binding protein CIN4", "aln": "MGLLSIIRKQKLRDKEIRCLILGLDNSGKSTIVNKLLPKDEQNNDGIMPTVGFQIHSLMIKDVTISLWDIGGQRTLRPFWDNYFDKTQAMIWCIDVSLSMRFDETLQELKELINRDENRIGYECAVIVVLNKIDLVEDKSELHRRCLLVESELKCLFKPDIRIELVKCSGVTGEGIDNLRDRLVESCHFTQ----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*::::* : :::::* *:*****:**:**:::: : * * **:**:*::* .. .:.:**:***::**.:* ***:.*:.::* :* : *::. :**: *: .:. .::::. ** ** * . :.. *. : : *.**** : * *: . ", "identical_positions": 54, "similar_positions": 68, "identity": "27.69%" }, { "cls_id": "homologset.agr.SGD:S000004747", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18265-1", "uniprot_id": "GSK3A_RAT", "id": "P18265-1", "name": "Glycogen synthase kinase-3 alpha", "aln": "MSGGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASVGAMGGGVGASSSGGGPSGSGGGGSGGPGAGTSFPPPGVKLGRDSGKVTTVVATLGQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLIIPIIYVKVYMYQLFRSLAYIHSQG-VCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKV----FKS-RTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDELRSLG-TQLPNNRPLPPLFNFSPGELSIQPSLNAILIPPHLRSPSG-----PATLTSSSQALTETQTGQDWQAPDAT-PTLTNSS-------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49840-1", "uniprot_id": "GSK3A_HUMAN", "id": "P49840-1", "name": "Glycogen synthase kinase-3 alpha", "aln": "MSGGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASVGAMGGGVGASSSGGGPGGSGGGGSGGPGAGTSFPPPGVKLGRDSGKVTTVVATLGQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQG-VCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKV----FKS-RTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDELRCLG-TQLPNNRPLPPLFNFSAGELSIQPSLNAILIPPHLRSPAG-----TTTLTPSSQALTETPTSSDWQSTDAT-PTLTNSS-------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2NL51-1", "uniprot_id": "GSK3A_MOUSE", "id": "Q2NL51-1", "name": "Glycogen synthase kinase-3 alpha", "aln": "MSGGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASVGAMGGGVGASSSGGGPSGSGGGGSGGPGAGTSFPPPGVKLGRDSGKVTTVVATVGQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLITPIIYIKVYMYQLFRSLAYIHSQG-VCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKV----FKSSKTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDELRRLG-AQLPNDRPLPPLFNFSPGELSIQPSLNAILIPPHLRSPAGPASPLTTSYNPSSQALTEAQTGQDWQPSDATTATLASSS-------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WV60-1", "uniprot_id": "GSK3B_MOUSE", "id": "Q9WV60-1", "name": "Glycogen synthase kinase-3 beta", "aln": "MSG------------RPRTTSFAES-----------CKPVQQPSAFGSMKVSR----------------------------------------DKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFG-ICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKV----FRP-RTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPN-VKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAA------ASPPANATAASDTNAGDRGQTNNAASASASNST-------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18266-1", "uniprot_id": "GSK3B_RAT", "id": "P18266-1", "name": "Glycogen synthase kinase-3 beta", "aln": "MSG------------RPRTTSFAES-----------CKPVQQPSAFGSMKVSR----------------------------------------DKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFG-ICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDMWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKV----FRP-RTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPN-VKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAA------ASPPANATAASDTNAGDRGQTNNAASASASNST-------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49841-1", "uniprot_id": "GSK3B_HUMAN", "id": "P49841-1", "name": "Glycogen synthase kinase-3 beta", "aln": "MSG------------RPRTTSFAES-----------CKPVQQPSAFGSMKVSR----------------------------------------DKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFG-ICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKV----FRP-RTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPN-VKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAA------ASTPTNATAASDANTGDRGQTNNAASASASNST-------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AVR7-1", "uniprot_id": "A0A8M3AVR7_DANRE", "id": "A0A8M3AVR7-1", "name": "Glycogen synthase kinase-3 beta", "aln": "MSG------------RPRTTSFAES-----------CKPVPQPSAFGSMKVSR----------------------------------------DKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGDKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPMVYVKLYMYQLFRSLAYIHSFG-ICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVSKQVFRP-RTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELREPN-VKLPNGREKPSLFNFTTQELSSNPTLASILIPAHARNQAG------ASTPTNPSATSDANSGDRSQTTTAASASASNTST------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18431-2", "uniprot_id": "SGG_DROME", "id": "P18431-2", "name": "Protein kinase shaggy", "aln": "MSG------------RPRTSSFAEG------------NKQSPSLVLGGVKTCS-----------------------------------------RDGSKITTVVATPGQGTDRVQEVSYTDTKVIGNGSFGVVFQAKLCDTGELVAIKKVLQDRRFKNRELQIMRKLEHCNIVKLLYFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQLFRSLAYIHSLG-ICHRDIKPQNLLLDPETAVLKLCDFGSAKQLLHGEPNVSYICSRYYRAPELIFGAINYTTKIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEVIKVLGTPTREQIREMNPNYTEFKFPQIKSHPWQKV----FRI-RTPTEAINLVSLLLEYTPSARITPLKACAHPFFDELRMEGNHTLPNGRDMPPLFNFTEHELSIQPSLVPQLLPKHLQNASGP----GGNRPSAGGAASIAASGSTSVSSTGSGASVEGSAQPQSQGTAAAAGSGSGGATAGTGGASAGGPGSGNNSSSGGASGAPSAVAAGGANAAVAGGAGGGGGAGAATAAATATGAIGATNAGGANVTDS----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P83101-1", "uniprot_id": "GSK3H_DROME", "id": "P83101-1", "name": "Putative glycogen synthase kinase-3 homolog", "aln": "--------------------------------------MASQSKNSG------------------------------------------------LTNKVTTVVATNAFGADVMSEISYTDAKVVGNGSFGVVFQAKMVPSNEMVAIKKVLQDRRFKNRELQIMRKLRHDNIITLKWFFFSSGEKRDEVYLNLVMEFLPETLYKVERQYARAKQTLPVNFVRLYMYQLLRSMGYLHSLG-FCHRDIKPQNMLLDSETGVLKLCDFGSAKQLISGEPNVSYICSRYYRAPELIFGSTDYTTKIDMWSAGCVMSELLLGQLIFPGDSGVDQIVEIVKVMGTPTSEQLHDMNPHYKQFKLPELKPHPWSKV----FRI-RTPAEAIDLVSKMLIYSPNARVSPLMGCAHPFFDELRQDPHQQLPNGRSLPPLFNFTDYEKTIEPDTMPLLLPRAQGSSTTKEPSAAHRNRNTAGEESPRKTEDSQKPATAALSKSPGPSGKALESPPGFLQHDLGNGDHVAVGTMPMEPLTLEQNHFAAESYAVGEDAEDNLEEDVGDENDYDYDDGGQCNSTYISDDMDEASESDDDDFEEEDEN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38615-1", "uniprot_id": "RIM11_YEAST", "id": "P38615-1", "name": "Serine/threonine-protein kinase RIM11/MSD1", "aln": "--------------------------------------MNIQSNNSPNLSNNI------------------------------------------VSKQVYYAHPPPTIDPNDPVQISFPTTEVVGHGSFGVVFATVIQETNEKVAIKKVLQDKRFKNRELEIMKMLSHINIIDLKYFFYER-DSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSKQEICSMNPNYMEHKFPQIKPIPLSRV----FKK--EDDQTVEFLADVLKYDPLERFNALQCLCSPYFDELKLDD-GKINQITTDLKLLEFDEN--------------VELG-------------HLSPDELSSVKKKLYPKSK------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: . .. ..: ::::. :*:*:******: : : : * *********:*******:**: * * **: * :**:. :.:**::***:::::*:::*: *:: : : . :: **:**::*: *:* . .*********:*:*.:* ************ ********************: :**..**:**:***::****** :***:**:**:**::*::***: ::: .***:* :.*:*::*. * :* *: ::: : : :* * * *...* . .:****: : : *::* : . ", "identical_positions": 142, "similar_positions": 109, "identity": "23.95%" }, { "cls_id": "homologset.agr.SGD:S000004750", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M2E9-1", "uniprot_id": "F1M2E9_RAT", "id": "F1M2E9-1", "name": "60S ribosomal protein L13", "aln": "MAPSRNGMILKPHFHKDWQP-VDTWFNQPARKIRRRKARQAKARRIAPRPASGPIRPIVRCPTVRYHTKVRAGRGFSLEELRVAGIHKKMARTIGISVDPRRRNKSTESLQANVQRLKEYCSKLILFPRKPSAPKKGDSSAEELKLATQLTGPVMPIRN-VYKKEKARAITEEEKNFKAFASLRMARANARLFGIRAKRAKEAAE-QDVEK---KK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41123-1", "uniprot_id": "RL13_RAT", "id": "P41123-1", "name": "Large ribosomal subunit protein eL13", "aln": "MAPSRNGMILKPHFHKDWQQRVDTWFNQPARKIRRRKARQAKARRIAPRPASGPIRPIVRCPTVRYHTKVRAGRGFSLEELRVAGIHKKMARTIGISVDPRRRNKSTESLQANVQRLKEYRSKLILFPRKPSAPKKGDSSAEELKLATQLTGPVMPIRN-VYKKEKARAITEEEKNFKAFASLRMARANARLFGIRAKRAKEAAE-QDVEK---KK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47963-1", "uniprot_id": "RL13_MOUSE", "id": "P47963-1", "name": "Large ribosomal subunit protein eL13", "aln": "MAPSRNGMILKPHFHKDWQQRVDTWFNQPARKIRRRKARQAKARRIAPRPASGPIRPIVRCPTVRYHTKVRAGRGFSLEELRVAGIHKKVARTIGISVDPRRRNKSTESLQANVQRLKEYRSKLILFPRKPSAPKKGDSSAEELKLATQLTGPVMPIRN-VYKKEKARVITEEEKNFKAFASLRMARANARLFGIRAKRAKEAAE-QDVEK---KK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P26373-1", "uniprot_id": "RL13_HUMAN", "id": "P26373-1", "name": "Large ribosomal subunit protein eL13", "aln": "MAPSRNGMVLKPHFHKDWQRRVATWFNQPARKIRRRKARQAKARRIAPRPASGPIRPIVRCPTVRYHTKVRAGRGFSLEELRVAGIHKKVARTIGISVDPRRRNKSTESLQANVQRLKEYRSKLILFPRKPSAPKKGDSSAEELKLATQLTGPVMPVRN-VYKKEKARVITEEEKNFKAFASLRMARANARLFGIRAKRAKEAAE-QDVEK---KK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90Z10-1", "uniprot_id": "RL13_DANRE", "id": "Q90Z10-1", "name": "Large ribosomal subunit protein eL13", "aln": "MAPSRNGMILNPHFHKDWQKRVRTWFNQPARKIRRRKARQAKARRIAPRPVSGPLRPVVRCPTIRYHTKVRAGRGFTLEELKAAGINKKVARTIGISVDSRRRNRSTESLQANVQRLKEYRTKLIIFPRKAAKPKKGDSTEEELKMATQLTGPVMPIKK-VHKKEKARVISEDEKNFKAFASLRMARANARLFGIRAKRAKEAAE-QDVEK---KK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41126-1", "uniprot_id": "RL13_DROME", "id": "P41126-1", "name": "Large ribosomal subunit protein eL13", "aln": "MGKG-NNMIPNQHYHKWWQRHVKTWFNQPARKVRRHANRVKKAKAVFPRPASGALRPVVRCPTIRYHTKLRAGRGFTLEELKGAGIGANFAKTIGIAVDRRRKNKSLESRQRNIQRLKEYRSKLILFPINEKKIRAGESSLEECKLATQLKGPVLPIKNEQPAVVEFREVTKDEKKFKAFATLRKARTDARLVGIRAKRAKEAAESEDAAKGDPKKAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40212-1", "uniprot_id": "RL13B_YEAST", "id": "P40212-1", "name": "Large ribosomal subunit protein eL13B", "aln": "MAISKNLPILKNHFRKHWQERVKVHFDQAGKKVSRRNARAARAAKIAPRPLD-LLRPVVRAPTVKYNRKVRAGRGFTLAEVKAAGLTAAYARTIGIAVDHRRQNRNQEIFDANVQRLKEYQSKIIVFP------RDGKAPEAEQVLSAAAT---FPIAQ-PATDVEARAVQDNGE--SAFRTLRLARSEKKFRGIREKRAREKAE-AEAEK---KK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . * : : *::* ** * . *:*..:*: *: * :* : *** . :**:**.**::*: *:******:* *:: **: *:****:** **:*:. * : *:****** :*:*:** : *.:. * ::: . :*: : : * : .: : .** :** **:: :: *** ***:* ** :. * ** ", "identical_positions": 78, "similar_positions": 62, "identity": "35.62%" }, { "cls_id": "homologset.agr.SGD:S000004751", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62249-1", "uniprot_id": "RS16_HUMAN", "id": "P62249-1", "name": "Small ribosomal subunit protein uS9", "aln": "MPSKG--PLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62250-1", "uniprot_id": "RS16_RAT", "id": "P62250-1", "name": "Small ribosomal subunit protein uS9", "aln": "MPSKG--PLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14131-1", "uniprot_id": "RS16_MOUSE", "id": "P14131-1", "name": "Small ribosomal subunit protein uS9", "aln": "MPSKG--PLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R8S7-1", "uniprot_id": "M0R8S7_RAT", "id": "M0R8S7-1", "name": "Small ribosomal subunit protein uS9", "aln": "MPSKG--PLQSVQVFGCKKTATAVAHCKGGNGLIKVNGRSLEMIELCTLQYKLLEPVLHLGKERFAGVDIQVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYNPTLPVADPRRCESKKFGSPGARALYQKSYR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W237-1", "uniprot_id": "RS16_DROME", "id": "Q9W237-1", "name": "Small ribosomal subunit protein uS9", "aln": "MQQKRREPVQAVQVFGRKKTATAVAYCKRGNGLLKVNGRPLEQIEPKVLQYKLQEPLLLLGKEKFAGVDIRVRVSGGGHVAQIYAIRQAISKALVAFYQKYVDEASKKEIKDILVQYDRTLLVGDPRRCEPKKFGGPGARARYQKSYR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX51-1", "uniprot_id": "RS16A_YEAST", "id": "P0CX51-1", "name": "Small ribosomal subunit protein uS9A", "aln": "MSAVP-----SVQTFGKKKSATAVAHVKAGKGLIKVNGSPITLVEPEILRFKVYEPLLLVGLDKFSNIDIRVRVTGGGHVSQVYAIRQAIAKGLVAYHQKYVDEQSKNELKKAFTSYDRTLLIADSRRPEPKKFGGKGARSRFQKSYR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :**.** **:*****: * *:**:**** .: :* *::*: **:* :* ::*:.:**:***.*****:*:*****:*:*.***::****** **:*:*. : .*: ** :.*.** *.****. ***: :*****", "identical_positions": 78, "similar_positions": 41, "identity": "52.7%" }, { "cls_id": "homologset.agr.SGD:S000004754", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BNA7-1", "uniprot_id": "EIF3I_RAT", "id": "B0BNA7-1", "name": "Eukaryotic translation initiation factor 3 subunit I", "aln": "MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDP-SQIDS----NEPYMKIPCND--SKITSAVWGPLGECIIAGHESGELNQYSAKSGE-VLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTSLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDPQYFEFEFEA--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13347-1", "uniprot_id": "EIF3I_HUMAN", "id": "Q13347-1", "name": "Eukaryotic translation initiation factor 3 subunit I", "aln": "MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDP-SQIDN----NEPYMKIPCND--SKITSAVWGPLGECIIAGHESGELNQYSAKSGE-VLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDPQYFEFEFEA--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QZD9-1", "uniprot_id": "EIF3I_MOUSE", "id": "Q9QZD9-1", "name": "Eukaryotic translation initiation factor 3 subunit I", "aln": "MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDP-SQIDS----NEPYMKIPCND--SKITSAVWGPLGECVIAGHESGELNQYSAKSGE-VLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDPQYFEFEFEA--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7ZV55-1", "uniprot_id": "EIF3I_DANRE", "id": "Q7ZV55-1", "name": "Eukaryotic translation initiation factor 3 subunit I", "aln": "MKPILLQGHERSITQIKYNREGDLLFSVAKDPIANVWYSVNGERLGTYNGHTGAVWCVDVDWDTKNVLTGSADNSCRLWDCETGKQLALLETSSAVRTCGFDFSGNIIMFSTDKQMGYQCFLNYYDLRDP-QQIED----NQPYISVPCSE--SKITSAVWGPLGEFVIAGHENGEINQFSAKSGE-VLKKAKEHTKQINDIQSSVDLTMIISASKDCTAKMFDSSTLEHVKTFKTERPVNSAAISPIMDHVVMGGGQEAMEVTTTSTRIGKFEARFFHAAYEEEFGRVKGHFGPINCVAFHPDGKSYSSGGEDGYVRIHYFDPHYFDFELEA--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O02195-1", "uniprot_id": "EIF3I_DROME", "id": "O02195-1", "name": "Eukaryotic translation initiation factor 3 subunit I", "aln": "MRPLMLQGHERSITQIKYNREGDLLFSCSKDQKPNVWYSLNGERLGTYDGHQGAVWCLDVDWESRKLITGAGDMTAKIWDVEYGTVIASIPTKSSVRTSNFSFSGNQAAYSTDKAMGQSCELFLIDVRNADSSLSE----QEPTLRIPMTE--SKITSMLWGPLDETIITGHDNGNIAIWDIRKGQKVVDSGTDHSAGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKTERPVNSAAISPIMDHVVLGGGQDAMEVTTTSTKAGKFDSRFFHLIYEEEFARLKGHFGPINSLAFHPDGKSYASGGEDGFVRVQTFDSTYFENIFE---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40217-1", "uniprot_id": "EIF3I_YEAST", "id": "P40217-1", "name": "Eukaryotic translation initiation factor 3 subunit I", "aln": "MKAIKLTGHERPLTQVKYNKEGDLLFSCSKDSSASVWYSLNGERLGTLDGHTGTIWSIDVDCFTKYCVTGSADYSIKLWDVSNGQCVATWKSPVPVKRVEFSPCGNYFLAILDNVMKNPGSINIYEIERDSATHELTKVSEEPIHKIITHEGLDAATVAGWSTKGKYIIAGHKDGKISKYDVSNNYEYVDSIDLHEKSISDMQFSPDLTYFITSSRDTNSFLVDVSTLQVLKKYETDCPLNTAVITPLKEFIILGGGQEAKDVTTTSANEGKFEARFYHKIFEEEIGRVQGHFGPLNTVAISPQGTSYASGGEDGFIRLHHFEKSYFDFKYDVEKAAEAKEHMQEAN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.: * ****.:**:***:******: :** .****:******* ** *::*.:*.* :: :**:.* : ::** . * :* : .*: *. ** *: * : ::. . ::* : : . * *.. .: :*:**..*:: :. .. : . * *.*:* * * * ::::*:* .: :.* :* *.:.*: *:*:*.::* :.:::****:* :*****:. ***::**:* :***:.*::*****:* :*: *:*.**:******::*:: *: **: : ", "identical_positions": 114, "similar_positions": 108, "identity": "32.85%" }, { "cls_id": "homologset.agr.SGD:S000004757", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DBG6-1", "uniprot_id": "RPN2_MOUSE", "id": "Q9DBG6-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "aln": "MAPPGSSAVFLLALTITASVQALTPTHYLTKQDVERLKASLDRPFTDLESAFYSIVGLSSLGVQVPDVKKACTFIKSNLDPSNVDSLFYAAQSSQVLSGCEISVSNETKELLLAAVSEDSPIAQIYHAVAALSGFGLPLASNEALGALTARLGKEETVLATVQALQTASHLSQQADLRNIVEEIEDLVARLDELGGVYLQFEEGLELTALFVAATYKLMDHVGTEPSMKEDQVIQLMNTIFSKKNFESLSEAFSVASAAAALSQNRYHVPVVVVPEGSTSDTQEQAILRLQVSNVLSQPLAQAAVKLEHAKSAATRATVLQKTPFSLVGNVFELNFKNVKLSSGYYDFSVRVEGDSRYIANTVELRVKISTEVGITNVDLSTVDKDQSIAPKTTRVTYPAKAKGTFIADSHQNFALFFQLVDVNTGAELTPHQTFVRLHNQKTGQEVVFVAEPDNKNVYKFELDTSERKIEFDSASGTYTLYLIIGDATLKNPILWNVADVVIKFPEEEAPSTVLSQSLFTPKQEIQHLFREPEKRPPTVVSNTFTALILSPLLLLFALWIRIGANVSNFTFAPSTVIFHLGHAAMLG----LMYIYWTQLNMFQTLKYLAVLGTVTFLAGNRMLAQHAVKRTAH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25235-1", "uniprot_id": "RPN2_RAT", "id": "P25235-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "aln": "MAPPGSSAVFLLALTITASTQALTPTHYLTKHDVERLKASLDRPFTSLESAFYSIVGLNSLGAQVPDVKKACAFIKSNLDPSNVDSLFYAAQSSQVLSGCEISVSNETRDLLLAAVSEDSSVAQIYHAVAALSGFGLPLASHEALGALTARLSKEETVLATVQALHTASHLSQQADLRNIVEEIEDLVARLDELGGVYLQFEEGLELTALFVAATYKLMDHVGTEPSIKEDQVIQLMNTIFSKKNFESLSEAFSVASAAAALSQNRYHVPVVVVPEGSASDTQEQAILRLQVSSVLSQPLAQAAVKLEHAKSVASRATVLQKMPFSLVGDVFELNFKNVKLPSGYYDFSVRVEGDNRYIANTVELRVKISTEVGITNVDLSTVDKDQSIAPKTTRVTYPAKAKGTFIADSHQNFALFFQLVDVNTGAELTPHQTFVRLHNQKTGQEVVFVAEPDNKNVYKFELDTSERKIEFDSASGTYTLYLIIGDATLKNPILWNVADVVIKFPEEEAPSTVLSQNLFTPKQEIQHLFREPEKRPPTVVSNTFTALILSPLLLLFALWIRIGANVSNFTFAPSTVIFHLGHAAMLG----LMYVYWTQLNMFQTLKYLAVLGTVTFLAGNRMLAQQAVKRTAH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04844-1", "uniprot_id": "RPN2_HUMAN", "id": "P04844-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "aln": "MAPPGSSTVFLLALTIIASTWALTPTHYLTKHDVERLKASLDRPFTNLESAFYSIVGLSSLGAQVPDAKKACTYIRSNLDPSNVDSLFYAAQASQALSGCEISISNETKDLLLAAVSEDSSVTQIYHAVAALSGFGLPLASQEALSALTARLSKEETVLATVQALQTASHLSQQADLRSIVEEIEDLVARLDELGGVYLQFEEGLETTALFVAATYKLMDHVGTEPSIKEDQVIQLMNAIFSKKNFESLSEAFSVASAAAVLSHNRYHVPVVVVPEGSASDTHEQAILRLQVTNVLSQPLTQATVKLEHAKSVASRATVLQKTSFTPVGDVFELNFMNVKFSSGYYDFLVEVEGDNRYIANTVELRVKISTEVGITNVDLSTVDKDQSIAPKTTRVTYPAKAKGTFIADSHQNFALFFQLVDVNTGAELTPHQTFVRLHNQKTGQEVVFVAEPDNKNVYKFELDTSERKIEFDSASGTYTLYLIIGDATLKNPILWNVADVVIKFPEEEAPSTVLSQNLFTPKQEIQHLFREPEKRPPTVVSNTFTALILSPLLLLFALWIRIGANVSNFTFAPSTIIFHLGHAAMLG----LMYVYWTQLNMFQTLKYLAILGSVTFLAGNRMLAQQAVKRTAH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02795-1", "uniprot_id": "OSTD_YEAST", "id": "Q02795-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MQFFKTLAALVSCISFVLAYVAQDVHVSFPSTAGKSRVMIGKVEPRIG-IDETVPTTITVED--------------------------PNEVIQVN---------------FAIESTNKPFQN------------------------------------------------------------------------------------TLLIGLPNKNLEMAFEPEIKDNGKLSMYKYRIDLAKLDAALLQEASRSPEPIKAT-----------------------------------------------------------------------------LILASSTAKPKENLFREILQLNLNFDVDHSDSSLVDK--FGIKPEIHHIFHAEPKRVAKPIAVIFVLIIFITILSLIVTWLNSCAAAFNNIPTGVTAVYFLGFIATIVGFEVIFARYYLGTSIFETLFSSLYLGAPGLLTSTKFLRSFGQTI---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :*:* :. . *** * .*. * .. * :: ::* :. :** . : .*: ::***: *:: *: :.: : : .: : :.* .:* . ::.: : :. .. * :: :::* . * **. * * . *. *: :: :: :: ::* :.: *:::.: * * **:*:*: ** .. :: *. :*: .:* *:. *:. * . * : * ::.**. * : :: *: .:*:** **: :*:..::* . . . ", "identical_positions": 58, "similar_positions": 115, "identity": "9.13%" }, { "cls_id": "homologset.agr.SGD:S000004758", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96LU5-1", "uniprot_id": "IMP1L_HUMAN", "id": "Q96LU5-1", "name": "Mitochondrial inner membrane protease subunit 1", "aln": "MLRGVLGKTFRLVGYTIQYGCIAHCAFEYVGGVVMCSGPSMEPTIQNS-DIVFAENLSRHFYGIQRGDIVIAKSPSDPKSNICKRVIGLEGDKILTTSP----------SDFFKS----HSYVPMGHVWLEGDNLQNSTDSRCYGPIPYGLIRGRIFFK-----------IWPLSDFGFLRASPNGHRFSDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CQU8-1", "uniprot_id": "IMP1L_MOUSE", "id": "Q9CQU8-1", "name": "Mitochondrial inner membrane protease subunit 1", "aln": "MLRGVLGKAFRLAGYTIQYGCIAHCAFEYVGGVVMCSGPSMEPTIQNS-DIVFAENLSRHFYGIQRGDIVIAKSPSDPKSNICKRVIGLEGDKILSTSP----------SDVFKS----RSYVPTGHVWLEGDNLQNSTDSRYYGPIPYGLIRGRIFFK-----------IWPFSDFGFLRDSPNGQRFSDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZWF3-1", "uniprot_id": "D3ZWF3_RAT", "id": "D3ZWF3-1", "name": "Mitochondrial inner membrane protease subunit", "aln": "MLRGVLGKAFRLAGYTIQYGCIAHCAFEYVGGVVMCSGPSMEPTIQNS-DIVFAENLSRHFYGIQRGDIVIAKSPSDPKSSICKRVIGLEGDKILADNP----------PDIFKS----RNYVPTGHVWLEGDNLENSTDSRCYGPVPYGLIRGRIFFK-----------IWPFSDFGFLRDSPNGHRFSDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VXR8-1", "uniprot_id": "Q9VXR8_DROME", "id": "Q9VXR8-1", "name": "Mitochondrial inner membrane protease subunit", "aln": "--MKILSRLGRLMRYTVAYAAITHCTFEYIGDFVLCKGPSMEPTLHSD-NVLLTERLSKHWRTYQPGDIVIAISPIKADQFICKRIVAVSGDQVLIQKPIPIEAEFSGNSDDKKKPVMVKDYVPRGHVWIEGDNKGNSSDSRYYGPIPVGLIRSRVLCR-----------IWPISEATGL------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28627-1", "uniprot_id": "IMP1_YEAST", "id": "P28627-1", "name": "Mitochondrial inner membrane protease subunit 1", "aln": "MTVGTLPIWSKTFSYAIRSLCFLHIIHMYAYEFTETRGESMLPTLSATNDYVHVLKNFQNGRGIKMGDCIVALKPTDPNHRICKRVTGMPGDLVLVDPSTIVNYVGDVLVDEERFG--TYIKVPEGHVWVTGDNLSHSLDSRTYNALPMGLIMGKIVAANNFDKPFWDGSIRNIWGFKWINNTFLDVQAKSN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : *:: .: * . * .. * ** **: : : . . :: : ** ::* .* ... ****: .: ** :* . * : ** ****: *** :* *** *..:* *** .::. * : : ", "identical_positions": 40, "similar_positions": 39, "identity": "20.83%" }, { "cls_id": "homologset.agr.SGD:S000004760", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LH61-1", "uniprot_id": "A0ABK0LH61_RAT", "id": "A0ABK0LH61-1", "name": "NAD(P)H oxidoreductase RTN4IP1, mitochondrial", "aln": "---------MEVLKTCVLRRNACAAVCFWRRKVITRPPYRGISTTSARSTVMPAWVIDKYGKNEVLRFTQNMMLPIIHYPNEVIIKVHAASVNPIDVNMRSGYGATALNMKRDPLHMKTKGEEFPLTLGRDVSGVVMECGLDVRY-FQPGDEVWAAVPPWK--QGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLN--------AKNCMGKRALILGASGGVGTFAIQVMKAWG--AHVTAVCSKDASELVRKLGADEVIDYTMGSVEEQLKSLKL-------FDFILDNVGGSTETWALNFLKKWSGATYVTLVTPFLLNMDRLGIADGMLQTGVTVGTKALKHLWQ-GVHYRWAFFMASGPYLDEIAELVDGGKELLNDSLCHGQPFRLFVTKGLPSPIKVRSHCVAVRSADSAGYRADLPFF----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q924D0-1", "uniprot_id": "RT4I1_MOUSE", "id": "Q924D0-1", "name": "NAD(P)H oxidoreductase RTN4IP1, mitochondrial", "aln": "---------MGVLKTCVLRRSACAAACFWRRTVIPKPPFRGISTTSARSTVMPAWVIDKYGKNEVLRFTQNMMLPIIHYPNEVIIKVHAASVNPIDVNMRSGYGATALNMKRDPLHMKTKGEEFPLTLGRDVSGVVMECGLDVKY-FQPGDEVWAAVPPWK--QGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLS--------DKNCKGKRALILGASGGVGTFAIQVMKAWG--AHVTAVCSKDASELVRKLGADEVIDYTLGSVEEQLKSLKL-------FDFILDNVGGSTETWALNFLKKWSGATYVTLVTPFLLNMDRLGVADGMLQTGVTVGTKALKHLWQ-GVHYRWAFFMASGPYLDEIAELVDAGK------------IRPVIERTFP-FSEVPEAFLKVERGHARGKTVVNVV-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWV3-1", "uniprot_id": "RT4I1_HUMAN", "id": "Q8WWV3-1", "name": "NAD(P)H oxidoreductase RTN4IP1, mitochondrial", "aln": "---------MEFLKTCVLRRNACTAVCFWRSKVVQKPSVRRISTTSPRSTVMPAWVIDKYGKNEVLRFTQNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSGYGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMECGLDVKY-FKPGDEVWAAVPPWK--QGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLN--------DKNCTGKRVLILGASGGVGTFAIQVMKAWD--AHVTAVCSQDASELVRKLGADDVIDYKSGSVEEQLKSLKP-------FDFILDNVGGSTETWAPDFLKKWSGATYVTLVTPFLLNMDRLGIADGMLQTGVTVGSKALKHFWK-GVHYRWAFFMASGPCLDDIAELVDAGK------------IRPVIEQTFP-FSKVPEAFLKVERGHARGKTVINVV-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T3C7-1", "uniprot_id": "RT4I1_DANRE", "id": "Q7T3C7-1", "name": "NAD(P)H oxidoreductase RTN4IP1, mitochondrial", "aln": "---------MLMCR----RWLVCSLRCHYR----------SFSFSAARRTVMPAWVIDKYGKNDVLRFTKNAALPIIHYPNEVVVKVHAAGLNPIDISMRGGYGAATMAMKRDPLNISQSGGEFPLILGRDVSGEIMECGLDVKY-FKPGDQVWAAIPPWK--QGSLAEFVVVSGNEVSHKPKSLRHDEAASIPYVAATAWSAIVNTGGLN--------KDNSAKKRVLILGGSGGVGTFAIQMVKAWG--AHVTVTCSQNAERLVRDLGADDVVDYTAGPVEKQLKNLEK-------FDLILDSIGGETEKWALDLLKPWSGAKFVTLITPFLQNTDRLGLADGMMQSAVTVGCKVVKNLRK-GVHYRWGFFAPSGSALDEVSEMVDAGK------------VRPVVEEVFS-FAQVPEAFQKVEQGHARGKTVVSIMEDQKE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IPZ3-1", "uniprot_id": "RT4I1_DROME", "id": "Q8IPZ3-1", "name": "NAD(P)H oxidoreductase RTN4IP1, mitochondrial", "aln": "MTAAGFNSILCLRQLVRLNRRQYSAPAKSVLSGSQTNDQATPPPTSKSADKMRGWQLHNYGDIDELQLSEMLKIPQIRCSNECLVRIRATAVNPIDLAMLRGYGATVLNKMR---CQPGDGIEFPLILGREFCGELVQTGMGVS--LPLGSRVWGVVPLQAT-IGSHAEYVAVPSYCLAPAPKELDDYEAASVLYAGLTAWSGLYITGGLGGPCGATTASGGGAHKRVLVLGGSGGVGTLAIQILKSQK--VQVLATCSENAIEMVRNLGADLVVDYNNPQAMEELCKYAP-------YDIVLDCAGQGGQKAAES---KYDFRQYITFSSPLLANIDKQGLGVGALKNVFDLFQTNVRSVTQRGGLVKWGFFSPAPQGIQFLQKLVEQRK------------LMPLIDSSYG-FSELPKAFEKMKSGHLRGKIVVKLREETGD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28625-1", "uniprot_id": "YIM1_YEAST", "id": "P28625-1", "name": "Protein YIM1", "aln": "---------------------------------------------MSDEIVTNKSVTYVNNTTPVTITSSELDLRSCYQDDEVVIEVHAAALNPIDFITHQLCNSYIF-------------GKYPKTYSRDYSGVIIKAGKDVDNRWKVGDKVNGMYSHIYGERGTLTHYLILNPAKDVPITHMVEVPKDENDPYDDFVYAAAWPLTFGTAFSTLYDFKKDWTSDSKVLVIGASTSVSYAFVHIAKNYFNIGTVVGICSKNSIERNKKLGYDYLVPYDEGSIVENVKKLKQSVLENDKFDMIFDSVGNHDFFPVIDQFLKPKAKNSFYVTIAGNNKADYKNISWRDFVS-LSSILKAINPFKK--YNWRFGHPYPPNNFIEVGNEMIKKGT------------YKPPIDSVYE-FDQYKEAIDRLMSNRAKGKVVVKMK-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : :* ::.::*:.:****. .: : ::* .*: .* ::: * .* *..* . . *: :.:: : .: : : . * . :. . * .:.*::*.* .*. ::: * * **::: . :.** * :: * ::: . :*:::* * . . . . . . : * .:. : . . . :. . : ::.. .. :: :::. . : : . : * . ", "identical_positions": 33, "similar_positions": 108, "identity": "7.43%" }, { "cls_id": "homologset.agr.SGD:S000004762", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68FY1-1", "uniprot_id": "NUP35_RAT", "id": "Q68FY1-1", "name": "Nucleoporin NUP35", "aln": "-----------------------------------------MAAFAVDPQAPTLGSEPMMLGSP---TSPKPGANAQFLPGFLMGDLPAPVTPQPRSISGPSVGVMEMRSPLLAGGSPPQPVVP-------------------------------AHKDKSGAPPVRSIYDDISSPGLGSTPLPSRRQANISVLQSPLVGVT-TPVTGQSMFSPAN--IGQPRKTTLSP--AQLDPFYTQGDSLTS--EDHLDDTWVTVFGFPQASASYILLQFAQYGNILKHVMS--------------------------NTGNWMHIRYQSKLQARKALSKDGRIFGESIMIGVKP----CIDKNVMENSDRGVLSSPSLAFTPPIRTLGTPTQPG-----STPRVSTMRPLATAYKASTS----------------------------------DYQVISDRQTPKKDESLVSRAMEYMFGW---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4R6-1", "uniprot_id": "NUP35_MOUSE", "id": "Q8R4R6-1", "name": "Nucleoporin NUP35", "aln": "-----------------------------------------MAAFAVDPQAPTLGSEPMMLGSP---TSPKTGANAQFLPGFLMGDLPAPVTPQPRSISGPSVGVMEMRSPLLAGGSPPQPVVP-------------------------------AHKDKSGAPPVRSIYDDISSPGLGSTPLTSRRQANISLLQSPLVGAT-TPVPGQSMFSPAN--IGQPRKTTLSP--AQLDPFYTQGDSLTS--EDHLDDTWVTVFGFPQASASYILLQFAQYGNILKHVMS--------------------------NTGNWMHIRYQSKLQARKALSKDGRIFGESIMIGVKP----CIDKNVMENSDRGVLSSPSLAFTTPIRTLGTPTQSG-----STPRVSTMRPLATAYKASTS----------------------------------DYQVISDRQTPKKDESLVSRAMEYMFGW---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFH5-1", "uniprot_id": "NUP35_HUMAN", "id": "Q8NFH5-1", "name": "Nucleoporin NUP35", "aln": "-----------------------------------------MAAFAVEPQGPALGSEPMMLGSP---TSPKPGVNAQFLPGFLMGDLPAPVTPQPRSISGPSVGVMEMRSPLLAGGSPPQPVVP-------------------------------AHKDKSGAPPVRSIYDDISSPGLGSTPLTSRRQPNISVMQSPLVGVTSTPGTGQSMFSPAS--IGQPRKTTLSP--AQLDPFYTQGDSLTS--EDHLDDSWVTVFGFPQASASYILLQFAQYGNILKHVMS--------------------------NTGNWMHIRYQSKLQARKALSKDGRIFGESIMIGVKP----CIDKSVMESSDRCALSSPSLAFTPPIKTLGTPTQPG-----STPRISTMRPLATAYKASTS----------------------------------DYQVISDRQTPKKDESLVSKAMEYMFGW---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P6X9-1", "uniprot_id": "NUP35_DANRE", "id": "Q6P6X9-1", "name": "Nucleoporin NUP35", "aln": "----------------------------------------------MEIQS---CIEPMTLGSP---TSPKPG--AQFLPGFLMGDLPAPVTPQPRSFG--LTGGAEIRSPLLAGGSPPQPVVP-------------------------------TPKDKSGAPPVRSIYDDLNGSAVGMSPLAARKQP-FAGVHTPLSGLQGTPGTVSNFFSP----VSQQRKTTLSP--AQVDPFFTQGDALSS--EDQLDDTWITVFGFPPASASYILLQFAQYGNILKHVMS--------------------------NTGNWMHVQYQSKLQARKALSKDGKIFGEAIMIGVKP----CIDKSVMESLDKGSTSSS--VFTPPVKAPCTPSHPL-----STPR-SVMRPLSAAYKASSS----------------------------------DYQVVSDQQTPKKDESFVSKAMEYMFGW---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWS2-1", "uniprot_id": "NUP35_DROME", "id": "Q9VWS2-1", "name": "Nucleoporin Nup35", "aln": "-------------------------------------------------------MEPMNLGSP---VNSPGSNQTQYLPPFLLGD-PQGITPHKNTLS-PKTGRSNISFATSPGGSSPHELNRSALSTRTLFA-AQGGAHTAVGANSSTTAHGQTHSHHQTGPPTQGLFDSLREQSVTPK---KKNHLGMLQLQSPNQSYQSSYHTNDSFAPGAPNAINASMRALCSPLGATASPAGGLGTSVTTGGNSRLSDFWVTIFGFPPGAGSMVLQHFTVCGTIVDVVHAP-------------------------QNGNWMYVRYSSRIESDKALNYNEKIIAGNVMVGVSR----CTDRSVIDKENIG---------SVPNAEIGDPPTSP-----SAIRPFSQQ----SYKLARK----------------------------------DNIISPQKDVPQKSSGLMDKAMDLIFGW---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03790-1", "uniprot_id": "NUP53_YEAST", "id": "Q03790-1", "name": "Nucleoporin NUP53", "aln": "MADLQKQENSSRFTNVSVIAPESQGQHEQQKQQEQLEQQKQPTGLLKGLNGFPSAPQPLFMEDPPSTVSGELNDNPAWFNNPRKRAIPNSIIKRSNGQSLSPVRSDSADVPAFSNSNGFNNVTFGSKKDPRILKNVSPNDNNSANNNAHSSDLGTVVFDSNEAPPKTSLADWQKEDGIFSSKTDNIEDPNLSSNITFDGKPTATPSPFRPLEKTSRILNFFDKNTKTTPNTASSEASAGSKEGAST----NWDDHAIIIFGYPETIANSIILHFANFGEILEDFRVIKDFKKLNSKNMSKSPSLTAQKYPIYTGDGWVKLTYKSELSKSRALQENGIIMNGTLIGCVSYSPAALKQLASLKKSEEIINNKTSSQTSLSSKDLSNYRKTEGIFEKAKAKAVTSKVRNAEFKVSKNSTSFKNPRRLEIKDGRSLFLRNRGKIHSGVLSSIESDLKKREQASKSKKSWLNRLNNWLFGWNDL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: : .* .. . . :: * : : . . . . . .... : : . . . .** .: * .: . .. : : : . : .: :* * .. . :: . .* : :**:* .. :: :*: * *:. . ..*: : *.*.:. :**. : *: :: *. : :.. : : . . : : : :* : . : : .:..:.... :.: : :*** ", "identical_positions": 26, "similar_positions": 106, "identity": "5.43%" }, { "cls_id": "homologset.agr.SGD:S000004763", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1S8-1", "uniprot_id": "CAN7_MOUSE", "id": "Q9R1S8-1", "name": "Calpain-7", "aln": "MDASALERDAVQFARLAVQRDHEGRYSEAVFYYKEAAQALIYAEMAGSSLERIQEKINEYLERVQALHSAVQSKSTDPLKSKHQLDLERAHFLVTQAFDEDEKGNVEDAIELYTEAVELCLKTSSETADKTLQNKLKQLARQALDRAEALSEPLTKPFCKLKSANMKTKTPPVRTHFPLGPNPFVEKPQAFISPQSCDAQGQKYTAEEIEVLRTTSKINGVEYVPFMSVDLRERFAYPMPFCDRLGKLPLSPKQKTTFSKWVRPEDLTNNPTMIYTVSSFSIKQTIVSDCSFVASLAISAAYERRFNKKLITSIIYPQNKDGEPEYNPCGKYMVKLHLNGVPRKVIIDDQLPVDHKGELLCSYSNNKSELWVSLIEKAYMKVMGGYDFPGSNSNIDLHALTGWIPERIAMHSDSQTFSKDNSFRMLYQRFHKGDVLITASTGVMTEAEGEKWGLVPTHAYAVLDIREFKGLRFIQLKNPWSHLRWKGRYSENDVKNWTPELQKYLNFDPRTAQKIDNGIFWISWDDLCQYYDVVYLSWNPALFKESTCIHSTWDAKQGPVKDAYSLANNPQYKLEVQCPQGGAAVWVLLSRHITDKDDFANNREFITMVVYKTDGKKVYYPADPPPYIDGIRINSPHYLTKIKLTTPGTHTFTLVVSQYEKQNTIHYTVRVYSACSFTFSKIPSPYTLSKRINGKWSGQSAGGCGNFQETHKNNPIYQFHIDKTGPLLIELRGPRQYSVGFEVVAVSIMGDPGPHGFQRKSSGDYRCGFCYLELENIPAGIFNIIPSTFLPKQEGPFFLDFNSTVPIKTTQLQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6W3-1", "uniprot_id": "CAN7_HUMAN", "id": "Q9Y6W3-1", "name": "Calpain-7", "aln": "MDATALERDAVQFARLAVQRDHEGRYSEAVFYYKEAAQALIYAEMAGSSLENIQEKITEYLERVQALHSAVQSKSADPLKSKHQLDLERAHFLVTQAFDEDEKENVEDAIELYTEAVDLCLKTSYETADKVLQNKLKQLARQALDRAEALSEPLTKPVGKISSTSVKPKPPPVRAHFPLGANPFLERPQSFISPQSCDAQGQRYTAEEIEVLRTTSKINGIEYVPFMNVDLRERFAYPMPFCDRWGKLPLSPKQKTTFSKWVRPEDLTNNPTMIYTVSSFSIKQTIVSDCSFVASLAISAAYERRFNKKLITGIIYPQNKDGEPEYNPCGKYMVKLHLNGVPRKVIIDDQLPVDHKGELLCSYSNNKSELWVSLIEKAYMKVMGGYDFPGSNSNIDLHALTGWIPERIAMHSDSQTFSKDNSFRMLYQRFHKGDVLITASTGMMTEAEGEKWGLVPTHAYAVLDIREFKGLRFIQLKNPWSHLRWKGRYSENDVKNWTPELQKYLNFDPRTAQKIDNGIFWISWDDLCQYYDVIYLSWNPGLFKESTCIHSTWDAKQGPVKDAYSLANNPQYKLEVQCPQGGAAVWVLLSRHITDKDDFANNREFITMVVYKTDGKKVYYPADPPPYIDGIRINSPHYLTKIKLTTPGTHTFTLVVSQYEKQNTIHYTVRVYSACSFTFSKIPSPYTLSKRINGKWSGQSAGGCGNFQETHKNNPIYQFHIEKTGPLLIELRGPRQYSVGFEVVTVSTLGDPGPHGFLRKSSGDYRCGFCYLELENIPSGIFNIIPSTFLPKQEGPFFLDFNSIIPIKITQLQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03792-1", "uniprot_id": "RIM13_YEAST", "id": "Q03792-1", "name": "Calpain-like protease 1", "aln": "----------------MNDWHEFNAAIKSIYCNAEGDSSSIINRLVGLAMK---SEDSTFIEAVLVLKENVS-------KVDKQLRFLWLTSTINSRFYPPIP--ISEASPVSWNKTEYCAPGTEELQRRYPG---RAKLQNEEDYSGGIEQCRDVPDCSLVASLINLRSKNLN-------LPLIKQISSTKYHVNLSFNGSNKRLVTVDISQIPTSVDGKQLS-----------LKSNDISDKIGELALLLVSKGTYS-----TDGSNISIDTYRLSGFLPEITQVNSYPFEK--------LWKFHKSNLCLMGAGTGNRSNDMIKPLVENHDYSIIDITYDSRLVKLRDPRNSALNVEISYEQYLKNFKQLYLNWNQEKLFKRSQVLHFRYDTSRYNKFSIVADKPLFHLVNNSKVTETVWLLLESHLQDEGSQENRSVSFLNEAP---ECIICPIEPPVECGGNHIGLQLVKLR-------------------LDAETERLLYCYSTTNNNFSIHSFSVVKEICFQRLKDTKSLFAKVLFSFPYEIEGKASFDTCNFFQNPTFELEVHSEQDYQVLMDAACISTSSHDLINIQVYYFNDYELIKPIMFDN----HYQPGQGLKQDVPILTNVKYMIVCSTYGPPASTEFELLASIRLSSSWRLISGITLRSVNLIYGTYPYHCRNRFHWKETSDKLKIQMTLPTKKYSTNKLFIRVVPVESSARLRMRCNIFEPESALCVYECQEYRTCPSGGIVIPDLEVSRTNIVVLMIERSVP-ISSCLP-TEGQLDELELFVGSSQKIRIEKYSDDVIPK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. . :::: *. .: * .:.* ::: .: . ::* * .*:. *. * .:** : :.. * :.:* : : .: * : * : : :: * : .:.: * .: :: :: :. :. *:::: .: . . :*.. ::: : .:.::* : . :.*: *:*.* .* *:* * :* . * :*.* : * *.. .* :*:*. : : .: .: :* : :: . . ::. : * : :: **.: .:: :: *:: :. . : . : . :.:: :* .:: .:. : :* .:::. . . *...:.** :: . .* :. **::::*: .* :: * . * :::. * : : * . : **. . *... . . . : :: : : : : * ..*.: . *. : : *: *:*. :::.. * *.: * * : :. . .*.: * *:.* ... : . : .: :.. * : : . . . :: .*: : :. ::.. * . : . .: * . . *: . * .: * :*. . * . :* * :* :*:. .. : *: . : ", "identical_positions": 86, "similar_positions": 277, "identity": "10.53%" }, { "cls_id": "homologset.agr.SGD:S000004765", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JUH4-1", "uniprot_id": "A0A0G2JUH4_RAT", "id": "A0A0G2JUH4-1", "name": "Bifunctional polynucleotide phosphatase/kinase", "aln": "------------MSELGSRGRLWLQSPTGGPPPIFLPSDGQALVLGRGPLTQVMDRKCSRNQVELIADPETRTVAVKQLGVNPSTVGVQELKPGVSGSLSVGDVLYLVNGLYPLTLRWEEIS-------------------------------------------------TPGSPPDTPPGNP-VDPEEGKDTE----------------PQKKRMRKSSPG-------WESFKQLLVFTASGVKPRGKVAAFDLDGTLITTRS-GKVFPTSPSDWRILYPEIPKKLQELAAEGYKLVILTNQMGIGRGKLPAEVFKAKVEAVLEKLGVPFQVLVATHAGLNRKPVSGMWDHLQEKGNEGIPISIGDSVFVGGSR-APSQLG-PREEEKGFLLCRPPGKPGFALNVGLPFATPEEFFLKWPAARFELPAFDPRTISSAGPLYLPESSFLLSPNPEVVVAVGFPGAGKSTFIQKHLVSAGYVHVNRDTLGSWQRCVNSCQAALRQGKQVVIDNTNPDIQSRARYIQCAKDAGVPCRCFSFCATIEQARHNNRFREMTDPS--HAPVSDMVMFSYRKQFEPPTLAEGFLEILQVPFRLQEHLDPALQRLYCQFSEG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLV6-1", "uniprot_id": "PNKP_MOUSE", "id": "Q9JLV6-1", "name": "Bifunctional polynucleotide phosphatase/kinase", "aln": "------------MSQLGSRGRLWLQSPTGGPPPIFLPSDGQALVLGRGPLTQVTDRKCSRNQVELIADPESRTVAVKQLGVNPSTVGVHELKPGLSGSLSLGDVLYLVNGLYPLTLRWEELS-------------------------------------------------TSGSQPDAPPDTP-GDPEEGEDTE----------------PQKKRVRKSSLG-------WESLKKLLVFTASGVKPQGKVAAFDLDGTLITTRS-GKVFPTSPSDWRILYPEIPKKLQELAAEGYKLVIFTNQMGIGRGKLPAEVFKGKVEAVLEKLGVPFQVLVATHAGLNRKPVSGMWDHLQEQANEGIPISVEDSVFVGDAAGRLANWA-PGRKKKDFSCADR----LFALNVGLPFATPEEFFLKWPAARFELPAFDPRTISSAGPLYLPESSSLLSPNPEVVVAVGFPGAGKSTFIQEHLVSAGYVHVNRDTLGSWQRCVSSCQAALRQGKRVVIDNTNPDVPSRARYIQCAKDAGVPCRCFNFCATIEQARHNNRFREMTDPS--HAPVSDMVMFSYRKQFEPPTLAEGFLEILEIPFRLQEHLDPALQRLYRQFSEG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96T60-1", "uniprot_id": "PNKP_HUMAN", "id": "Q96T60-1", "name": "Bifunctional polynucleotide phosphatase/kinase", "aln": "------------MGEVEAPGRLWLESPPGGAPPIFLPSDGQALVLGRGPLTQVTDRKCSRTQVELVADPETRTVAVKQLGVNPSTTGTQELKPGLEGSLGVGDTLYLVNGLHPLTLRWEETR-------------------------------------------------TPESQPDTPPGTPLVSQDEKRDAE----------------LPKKRMRKSNPG-------WENLEKLLVFTAAGVKPQGKVAGFDLDGTLITTRS-GKVFPTGPSDWRILYPEIPRKLRELEAEGYKLVIFTNQMSIGRGKLPAEEFKAKVEAVVEKLGVPFQVLVATHAGLYRKPVTGMWDHLQEQANDGTPISIGDSIFVGDAAGRPANWA-PGRKKKDFSCADR----LFALNLGLPFATPEEFFLKWPAAGFELPAFDPRTVSRSGPLCLPESRALLSASPEVVVAVGFPGAGKSTFLKKHLVSAGYVHVNRDTLGSWQRCVTTCETALKQGKRVAIDNTNPDAASRARYVQCARAAGVPCRCFLFTATLEQARHNNRFREMTDSS--HIPVSDMVMYGYRKQFEAPTLAEGFSAILEIPFRL--WVEPRLGRLYCQFSEG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IRS4-1", "uniprot_id": "A0A0R4IRS4_DANRE", "id": "A0A0R4IRS4-1", "name": "Bifunctional polynucleotide phosphatase/kinase", "aln": "-------------MEMQCT----LVSVDGDR--VVLP-DGRALMFGRGPESRISDKKCSRHQVKLVADYAKQEVLVTQLGPNPSSLDGQCLGRGESGCLTTGQTLYLVNESYPFTVEFAFHCGIQLSSSPQKKEKITNESKQRQKSSKESSGSLKRNIHDYFSKSPKKAAKRPYSPEDDVPQPKRGREDEDNEDEGTSAEQKLQQLQAFAQSESDNFKSSNPSSTCSQSHWQQIGSLMLFTAAGVTASSKIAGFDIDGCIITTKS-GKVFPTGPDDWRILYPEIQPKLASLLKKGYKVVFFTNQMGISRGKLRPEVFKSKAEDILQTLQLPIQVFVSTAPGIYRKPVIGMWEHLCEKANSGVMVDVSESFYVGDAAGRPANWA-PGKKKKDFSCSDR----LFALNIGLQFYTPEEYFLGWKPATFSFPEFDPRKLDSKARLYDPPDASLTSTKQEIIVAVGFPGAGKSTFFQTHIIPKGYAYVNRDTMGSWQHCVSACERALKEGKSVAVDNTNPDLESRKRYIDVAQSAGVSCRCFNFTASLDQAKHNNRFREMVPSATKHVPVNDMVIHSYKKKFVVPSLSEGFSEVLQIHFVP-SFSDKRSEFLFKQFSEG-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHS0-1", "uniprot_id": "Q9VHS0_DROME", "id": "Q9VHS0-1", "name": "", "aln": "MSMAKYLNRSVGKAGKDVAARICTLKPTEPEHHSIHLTAGEN-FVGRSRETGIRDSKCSKRQIQLQVDLKKAVVSLKVLGVNPCGVNGLMLMQNGERELKHGDLVEIVYGRHQFEVVFNPPP--------------------------------------------------EYDKEKAEPLSTTLSPSE----------------------KSERWDSSGNG------------KLVIFTSVGVKGSEKIAGYDMDGTIIKTKS-GLVFPKNTDDWQIIFPEVPEKLKNLHKDGFKICLFTNQGGIARGKINLDDFKVKIKHIVAKLGVPIQVFIAIGDGFYRKPLTGMWQHLKSEMNDGVEIQEDRCFFVGDAAGRPETGKGATKRRKDHSLVDR----LFAANVGISFYTPEVHFLGKQVEQWNKPDFEPTSVQDQVSLLDPDDLTLDDHPCEMVIMVGLPGSGKSHFCSSFFQPRGYKIVNADTLGSTQNCLTACKRFLDSGQSCVVDNTNVDAASRKKFLQLASEKMIPCRCLVMNVPVAQVKHNIAFRELSDSAR--TKIKDMVFNMMKKKYQEPALDEGFISIHKVNFKP-NFADEKQEKLYKMYLVEK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03796-1", "uniprot_id": "TPP1_YEAST", "id": "Q03796-1", "name": "Polynucleotide 3'-phosphatase", "aln": "----------------------------------------------------------------------------------------------MSHKLTILPFLIKFTPKFPQSIDHDEHG------------------------------------------------------------------------------------------------------------------------------LNVYAFDLDHTIIKPKSPNISFSRSASDWQFINFNSKKSTLDYLCN-----IIDND-------------PTAVIVIFSNQGGVITVPRTSKS--CTKYTNKILLFLKAIKNDERGETLSHRLWLYAAPKRPKTFA--------------------ANHSKITFASLGESYN---------------------------------NDPNIFEKVRKPMTGMVEFFKRDLES--AYRVSEQISPIKLNWIYYCG----------------DAAGRK-------------------------------KDFSDSD------------------------IKFAENLHVEFKY-------PEEIFHG-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : . . : :: .:*:* :*..:* . *. ...**::: : . . . :: *: :. . : * : * : .* *. .:: : * : : * : : ::. * * :* * . : . *. : . : * * .* ::: . * .: * :: ", "identical_positions": 25, "similar_positions": 65, "identity": "4.06%" }, { "cls_id": "homologset.agr.SGD:S000004771", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q149L6-1", "uniprot_id": "DJB14_MOUSE", "id": "Q149L6-1", "name": "DnaJ homolog subfamily B member 14", "aln": "MEGNRDEAEKCVQIAREALSAGNRDKAQRFLQKAEKLYPLPAARALLEIIMKNGSTAGS---STHCRKPPGSSDQSKPSCGKDGTSGAGEGGKVYTKDQVEGVLSINKCKNYYEVLGVTKDAGDEDLKKAYRKLALKFHPDKNHAPGATDAFKKIGNAYAVLSNPEKRKQYDLTGSEEQACNHQNNG------------RFNFHRGCEADITPEDLFNIFFGGGFPSGSVHSFSNGRAAYSHQHQHRHSGHEREEERADGGFSVFIQLMPIIVLILVSLLSQLMVSNPPYSLYPRSGSGQTIKMQTENLGVVYYVSKDFKSEYKGTLLQKVEKSVEEDYVTNIRNNCWKERQQKTDMQYAAKVYRDEQLRRKADALSMENCKELERLTSLYKGG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JTM9-1", "uniprot_id": "A0A0G2JTM9_RAT", "id": "A0A0G2JTM9-1", "name": "DnaJ homolog subfamily B member 14", "aln": "MEGNRDEAEKCVQIAREALSAGNRDKAQRFLQKAEKLYPLPAARALLEIIMKNGSTAGN---STHCRKPPGSSDQSKPSFGKDGTSGAGEGGKVYTKDQVEGVLSINKCKNYYEVLGVTKDAGDEDLKKAYRKLALKFHPDKNHAPGATDAFKKIGNAYAVLSNPEKRKQYDLTGSEEEACSPQSNG------------RFNFHRGCEADITPEDLFNIFFGGGFPSGSVHSFSNGRAAYSHQHQHRHSGHEREEERGDGGFSVFIQLMPVIVLILVSLLSQLMVSNPPYSLYPRSG--QTIKMQTENLGVVYYVNKDFKSEYKGALLQKVEKSVEEDYVTNIRNNCWKERQQKTDMQYAAKVYRDERLRRKADALSMDNCKELERLTSLYKGG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TBM8-1", "uniprot_id": "DJB14_HUMAN", "id": "Q8TBM8-1", "name": "DnaJ homolog subfamily B member 14", "aln": "MEGNRDEAEKCVEIAREALNAGNREKAQRFLQKAEKLYPLPSARALLEIIMKNGSTAGN---SPHCRKPSGSGDQSKPNCTKDSTSGSGEGGKGYTKDQVDGVLSINKCKNYYEVLGVTKDAGDEDLKKAYRKLALKFHPDKNHAPGATDAFKKIGNAYAVLSNPEKRKQYDLTGNEEQACNHQNNG------------RFNFHRGCEADITPEDLFNIFFGGGFPSGSVHSFSNGRAGYSQQHQHRHSGHEREEERGDGGFSVFIQLMPIIVLILVSLLSQLMVSNPPYSLYPRSGTGQTIKMQTENLGVVYYVNKDFKNEYKGMLLQKVEKSVEEDYVTNIRNNCWKERQQKTDMQYAAKVYRDDRLRRKADALSMDNCKELERLTSLYKGG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QYI4-1", "uniprot_id": "DJB12_MOUSE", "id": "Q9QYI4-1", "name": "DnaJ homolog subfamily B member 12", "aln": "MESNKDEAERCISIALKAIQSNQPERALRFLEKAQRLYPTPRVSALIESLNQKPQSTGDHPQPTDTTHTTTKKAGGTETPSANGEAGGGESAKGYTSEQVAAVKRVKQCKDYYEILGVSRSASDEDLKKAYRKLALKFHPDKNHAPGATEAFKAIGTAYAVLSNPEKRKQYDQFGDDKSQAARHGHS------------HGDFHRGFEADISPEDLFNMFFGGGFPSSNVHVYSNGRMRYTYQQRQ-----DRRDNQGDGGLGVFVQLMPILILILVSALSQLMVSSPPYSLSPRPSVGHIHKRVTDHLNVAYYVADTFSEEYTGSSLKTVERNVEDDYIANLRNNCWKEKQQKEGLLYRARYFGDTDMYHRAQKMGTPSCNRLSEVQASLHG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F4L4-1", "uniprot_id": "F7F4L4_RAT", "id": "F7F4L4-1", "name": "", "aln": "MESNKDEAERCISIALKAIQSNQPDRALRFLEKAQRLYPTPRVTALIESLNQKSQSAGDQSQPTDTTHTTTRKTSGTETPSANGEAGGGESTKGYTSEQVAAVKRVKQCKDYYEILGVSRSASDEDLKKAYRKLALKFHPDKNHAPGATEAFKAIGTAYAVLSNPEKRKQYDQFGDDKNQAARHGHS------------HGDFHRGFEADISPEDLFNMFFGGGFPSSNVHVYSNGRMRYTYQQRQ-----DRRDNQGDGGLGVFVQLMPILILILVSALSQLMVSSPPYSLSPRPSVGHIHKRVTDHLNVAYYVADTFSEEYTGSSLKTVERNVEDDYIANLRNNCWKEKQQKEGLLYRARYFGDTDMYHRAQKMSTPSCSRLSEVQASLHG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NXW2-1", "uniprot_id": "DJB12_HUMAN", "id": "Q9NXW2-1", "name": "DnaJ homolog subfamily B member 12", "aln": "MESNKDEAERCISIALKAIQSNQPDRALRFLEKAQRLYPTPRVRALIESLNQKPQTAGDQPPPTDTTHATHRKAGGTDAPSANGEAGG-ESTKGYTAEQVAAVKRVKQCKDYYEILGVSRGASDEDLKKAYRRLALKFHPDKNHAPGATEAFKAIGTAYAVLSNPEKRKQYDQFGDDKSQAARHGHG------------HGDFHRGFEADISPEDLFNMFFGGGFPSSNVHVYSNGRMRYTYQQRQ-----DRRDNQGDGGLGVFVQLMPILILILVSALSQLMVSSPPYSLSPRPSVGHIHRRVTDHLGVVYYVGDTFSEEYTGSSLKTVERNVEDDYIANLRNNCWKEKQQKEGLLYRARYFGDTDMYHRAQKMGTPSCSRLSEVQASLHG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFP0-1", "uniprot_id": "Q9VFP0_DROME", "id": "Q9VFP0-1", "name": "J domain-containing protein", "aln": "MDGNKDEAQRCIDFAVQALAAGKIEKAEKFLLKAERLFPTDNAKKLLAQLKSTPSNESN-----GKSRTAGASDEKDSGPRKRVNSDSRSSAPDYTKDQLEAVRKVKTCKDYYEVLGVSKTATDSEIKKAYKKLALQLHPDKNKAPGAVEAFKALGNAAGVLTDAEKRKNYDLYGINESHNGHGNNGGGHHGHGQYYNNEYGYSRGFQADISAEELFNMFFNGGFPQQNVHMRQQRRRQQARE--------DREGNNS----SALVNLLPIVLLIGLSMMSSFFISDPMYSLTPSHK--YSVKRETNSLKVPYYVKDNFYSEYQG-SVARLEESVEEDFVNHLKHSCSRERNYRDSMLAKARTFGDRDLYRKAQNINTPSCENLQKYLIT----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48353-1", "uniprot_id": "HLJ1_YEAST", "id": "P48353-1", "name": "Protein HLJ1", "aln": "------------------------------------------------------------------------------------------MSFTEDQEKIALEILSKDKHEFYEILKVDRKATDSEIKKAYRKLAIKLHPDKNSHPKAGEAFKVINRAFEVLSNEEKRSIYDRIGRDPDDRQMPSRG-----------AASGFRGSAGGSPMGGGFEDMFFNSRFGGQRAGPPED--------------------------------IFDFLFNAGGSPFGASPFGPSASTFSFGGP--GGFRVYTNNRGGSPFMRQ------QPRSRQQQQQAEENAVNSQLKNMLVLFIIFIVLPMIKDYLFS-----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: : :::**:* * : * *.::****::**:::***** * * :*** :. * **:: ***. ** * : . ... .: . .. : ::**.. * . .: :: .:. * :. .. . :: : *: :: . :. *: :::: : ", "identical_positions": 37, "similar_positions": 66, "identity": "9.39%" }, { "cls_id": "homologset.agr.SGD:S000004772", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZW0-1", "uniprot_id": "AT11C_MOUSE", "id": "Q9QZW0-1", "name": "Phospholipid-transporting ATPase 11C", "aln": "--------------------------------------------------------------------------------------MFRRTLN--RLCAGEEK------------------RVGTRTVFVGN-HPISGTE---PYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPTS-PVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSAVYIIENA--------------------------------------------------------------KRVRKESEKIKVGDVVEVQANETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDT-IALCTAESIDNLRATIECEQPQPDLYRFVGRISIYSNSIEA-----VARSLGPENLLLKGATLKNTKKIYGVAVYTGMETKMALNYQGKSQKCSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSSPYNDEPWYNQKTQKERETFQVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFFDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKG--TTQEVDGLSQTD-------------GPL-AYFDKAD-----------------KNREALFLRALCLCHTVEMKTN----------------------------DDVDGPVEGAGFT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YISSSPDEIALVKGAKRFGFTFLGNQNGYIRVENQRK-----------EIEEYELLHTLNFDSVRRRMSVIVRTQK--GDILLFCKGADSSIFPRVHSH---------------------------------------------------------------------------------------------------------------------------------------------------------------------QIELTKDHVERNAMDGYRTLCVAFKEIPPDDFERINAQLVEAKMALQDREEKLEKVFDEIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEES-ERKEDRLHELLIEYRKKLLHEFP-KSTRSLKKAWTEHQEYGLIIDGSTLSLILNSSQDCSSN--NYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLVHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTADPRLYMKITGNAMLQLGPFLHWTFLAAFEGTVFFFGTYFLF-QTSSLEDNGK--------IYGNWTFGTIVFTVLVFTVTLK-LALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLCSVSTWLAIILLIFISLFPEILLIVVKNVRRRSARRNLSCR--------------RASDSLSARPSVR-------PLLLRTFSDESNIL------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AFP3-1", "uniprot_id": "A0A8I6AFP3_RAT", "id": "A0A8I6AFP3-1", "name": "Phospholipid-transporting ATPase", "aln": "--------------------------------------------------------------------------------------MFRRTLN--RLCAGEEK------------------RVGTRTVFVGN-HPISGTE---AYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPTS-PVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENA--------------------------------------------------------------KRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDT-IELCTAESIDNLRAAIECEQPQPDLYKFVGRISIYSNSIEA-----VARSLGPENLLLKGATLKNTKKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETFKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFFDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKG--TTQEVDGLSQID-------------GPL-AYFDKAD-----------------KNREELFLRALCLCHTVEIKTN----------------------------DAVDGPIEGAQFT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YISSSPDEIALVKGAQKFGFTFLGNWNGHIRVENQRK-----------EIEEYELLHTLNFDSVRRRMSVIVRTQG--GDILLFCKGADSSIFPRVHSH---------------------------------------------------------------------------------------------------------------------------------------------------------------------EIDLTKVHVERNAMDGYRTLCVAFKEIPPDDFERINVQLIEAKMALQDREEKLEKIFDVIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEES-ERKEDRLHELLIEYRKKLLHEFP-KSTRSLKKAWTEHQEYGLIIDGSTLSLILNSSQDCSSN--NYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDALTADPRLYMKITGNAMLQLGPFLYWTFLAAFEGTVFFFGTYFLF-QTTSLEDNGK--------IYGNWTFGTIVFTVLVFTVTLK-LALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFISLFPEILLIVVKNVRRRSARRNLSCR--------------RASDSLSARPSVR-------PLLLRTFSDESNIL------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NB49-1", "uniprot_id": "AT11C_HUMAN", "id": "Q8NB49-1", "name": "Phospholipid-transporting ATPase IG", "aln": "-------------------------------------------------------------------------------------MQMVPSLPPASECAGEEK------------------RVGTRTVFVGN-HPVSETE---AYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPTS-PVTSGLPLFFVITVTAIKQGYEDCLRHRADNEVNKSTVYIIENA--------------------------------------------------------------KRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDT-IALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEA-----VARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKG--VTQEVDGLSQTD-------------GTL-TYFDKVD-----------------KNREELFLRALCLCHTVEIKTN----------------------------DAVDGATESAELT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRK-----------EIEEYELLHTLNFDAVRRRMSVIVKTQE--GDILLFCKGADSAVFPRVQNH---------------------------------------------------------------------------------------------------------------------------------------------------------------------EIELTKVHVERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEES-ERKEDRLHELLIEYRKKLLHEFP-KSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSN--NYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFLYWTFLAAFEGTVFFFGTYFLF-QTASLEENGK--------VYGNWTFGTIVFTVLVFTVTLK-LALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFISLFPEILLIVLKNVRRRSARRNLSCR--------------RASDSLSARPSVR-------PLLLRTFSDESNVL------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PUH0-1", "uniprot_id": "A0A8M9PUH0_DANRE", "id": "A0A8M9PUH0-1", "name": "Phospholipid-transporting ATPase", "aln": "--------------------------------------------------------------------------------------MLRRRLN--RLCGGDER------------------RVDSRTIYVGH-RPCPDTE---AFIPPKFCDNRIVSSKYTVWNFLPKNLFEQFRRIANFYFLIIFLVQVIVDTPTS-PVTSGLPLFFVITVTAIKQGYEDWLRHKADNEVNKYPVTVLEDG--------------------------------------------------------------RSVKKESEKIKVGDVVEVVEDETFPCDLILLQSSREDGTCFVTTASLDGESNHKTHYTVPD------IERDLQVLTAAIECEQPQPDLYKFVGRMHIYKPEQEE-----AVRSLGPENLLLKGATLKNTKEIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLLVYLCILISKAVVCTTLKYVWQSKEGQDEPWYNEKTQKEKETNMYLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFIKWDNDFFDPEIEEGALVNTSDLNEELGQVEYVFTDKTGTLTQNNMEFIECCIDGFQYRHRDAHGELDGFTVTD-------------GPLNKLQEKAG-----------------REKEELFLRALCLCHTVQVKEET----------------------LSDQIDGIDGVLPKAEEERG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FIASSPDEVALVKGAMEYGFTFLGLENKNMKIRNRQN-----------DIEEYKLLHVLNFDPVRRRMSVIVQTKS--GDTLLFCKGADSSIFPRVRPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------EVDRIRLQVERNATDGYRTLCVAYKQLSAEEYALADTGLREARLALQDREEKLMAMYNQVETGMSLIGATAVEDRLQEEAAETMEALQGAGMKIWVLTGDKMETAKSTCYACRLFQRGTELLELTVRTLEDGRSKREDRLLELLRDYHRRAVQDAPPVKTGVVTRSWSANQEYGFIIDGATLSLVMNPPRDADAS--LYRGLFLQICQNCTAVLCCRMAPLQKAQIVKMVKNCKGSPITLSIGDGANDVSMILEAHVGIGIKGKEGRQAVRNSDYAIPKLKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGYSQQPLYDAAYLTMYNICFTSMPILAYSLLEQHIAIEILLDNATLYREIAKNAMLRWRPFLYWTVLGIFQGLLFFFGVRFLF-SNPALQDNGQ--------VFGNWSYGTIVFTVLVFTVTLK-LALDTRHWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRLYFVFANMLSSVSAWLVIIILILLSLLPEILLAVLRKPKGPHSRQKKPGQS-------------NVGGIPSSQSSAR-------PLLMRTFSDESNTVI-----------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P98197-1", "uniprot_id": "AT11A_MOUSE", "id": "P98197-1", "name": "Phospholipid-transporting ATPase IH", "aln": "-----------------------------------------------------------------------------------MDCSLLRTLVR-RYCAGEEN------------------WVDSRTIYVGHKEPPPGAE---AYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTS-PVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHG--------------------------------------------------------------KLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRADGTCHVTTASLDGESSHKTHYAVQDT-KGFHTEADVDSLHATIECEQPQPDLYKFVGRINVYNDLNDP-----VVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNTFLIVYLCILVSKALINTVLKYVWQSEPFRDEPWYNEKTESERQRNLFLRAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEEMGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMAFKECCIEGHVYVP---HVICNGQVLPD-------------SSGIDMIDSSPG-------------VCGREREELFFRAICLCHTVQVKDDH----------------------CGDDVDGPQKSPD--AKSCV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNREN-----------DIERFELLEVLTFDSVRRRMSVIVKSTT--GEIYLFCKGADSSIFPRVIEG---------------------------------------------------------------------------------------------------------------------------------------------------------------------KVDQVRSRVERNAVEGLRTLCVAYKRLEPEQYEDACRLLQSAKVALQDREKKLAEAYEQIEKDLVLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETASATCYACKLFRRSTQLLELTTKKLEEQ------SLHDVLFDLSKTVLRCSGSMTRDSFSGLSTDMHDYGLIIDGAALSLIMKPREDGSSS-GNYRELFLEICRNCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDIAKNALLRWRVFIYWTFLGVFDALVFFFGAYFIF-ENTTVTINGQ--------MFGNWTFGTLVFTVMVLTVTLK-LALDTHYWTWINHFVIWGSLLFYIAFSLLWGGVIWPFLSYQRMYYVFISMLSSGPAWLGIILLVTVGLLPDVLKKVLCRQLWPTATERTQNIQ--HQDSISEFTPLASLPSWGAQGSR---------LLAAQCSSPSGRVVCSRWESE-ECPVLPLHPGLPHKARYGCCRSSLEMPT-----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A7K5-1", "uniprot_id": "D4A7K5_RAT", "id": "D4A7K5-1", "name": "Phospholipid-transporting ATPase", "aln": "-----------------------------------------------------------------------------------MDCSLLRTLVR-RYCAGEEN------------------WVDSRTIYVGHKEPPPGAE---AYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTS-PVTSGLPLFFVITVTAIKQGYEDWLRHKADSAMNQCPVHFIQHG--------------------------------------------------------------KLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRADGTCHVTTASLDGESSHKTHYAVQDT-KGFHTEADVDSLHATIECEQPQPDLYKFVGRINVYNDLNDP-----VVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNTFLIVYLCILVSKALINTVLKYVWQSEPFRDEPWYNQKTESERQRNLFLRAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEEMGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMAFKECCIEGHVYVP---HVICNGQVLPD-------------SSGIDMIDSSPG-------------VSGREREELFFRAICLCHTVQVKDDH----------------------CGDDVDGPQKSPD--AKSCV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YISSSPDEVALVEGMQRLGFTYLRLKDNYMEILNREN-----------DIERFELLEVLTFDSVRRRMSVIVKSTT--GEIYLFCKGADSSIFPRVIEG---------------------------------------------------------------------------------------------------------------------------------------------------------------------KVDQVRSRVERNAVEGLRTLCVAYKRLEPEQYEDACRLLQDAKVALQDREKKLAEAYEQIEKDLILLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETASATCYACKLFRRSTQLLELTTKKLEEQ------SLHDVLFELSKTVLRCSGSLTRDSFSGLSTDMHDYGLIIDGAALSLIMKPREDGSSS-GNYRELFLEICRNCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPSLYRDIAKNALLRWRLFIYWTFLGVFDALVFFFGAYFMF-ENTTVTINGQ--------MFGNWTFGTLVFTVMVFTVTLK-LALDTHYWTWINHFVIWGSLLFYIVFSLLWGGIIWPFLSYQRMYYVFIYMLSSGPAWLGIILLVTVGLLPDVLKKVLCRQLWPTATERTQTVQ--LRDSISEFTPLASLQSRGAQGTR---------LLAAQCSSPSGRVVCSRWESE-EYPVLPTHPGLLHKARYGCCRSSLETPT-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P98196-1", "uniprot_id": "AT11A_HUMAN", "id": "P98196-1", "name": "Phospholipid-transporting ATPase IH", "aln": "-----------------------------------------------------------------------------------MDCSLVRTLVH-RYCAGEEN------------------WVDSRTIYVGHREPPPGAE---AYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIFLVQLIIDTPTS-PVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHG--------------------------------------------------------------KLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDT-KGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDP-----VVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVP---HVICNGQVLPE-------------SSGIDMIDSSPS-------------VNGREREELFFRALCLCHTVQVKDD-------------------------DSVDGPRKSPDG-GKSCV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNREN-----------HIERFELLEILSFDSVRRRMSVIVKSAT--GEIYLFCKGADSSIFPRVIEG---------------------------------------------------------------------------------------------------------------------------------------------------------------------KVDQIRARVERNAVEGLRTLCVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQLLELTTKRIEEQ------SLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSS--GNYRELFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVFIYWTLLGLFDALVFFFGAYFVF-ENTTVTSNGQ--------IFGNWTFGTLVFTVMVFTVTLK-LALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQMLSSGPAWLAIVLLVTISLLPDVLKKVLCRQLWPTATERVQTKS--QCLSV-------------EQSTI---------FMLSQTSS------------------------------------SLSF-------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q0D3-1", "uniprot_id": "A0A8M9Q0D3_DANRE", "id": "A0A8M9Q0D3-1", "name": "Phospholipid-transporting ATPase", "aln": "-----------------------------------------------------------------------------------MDFSTIRNLIT-RYCTGEEN------------------WVDSRTVYIGHKEPPPGTE---AYIPQRFPDNRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTS-PMTSGLPLFFVITVTAIKQGYEDWIRHKADNSVNQCPVHIVQHG--------------------------------------------------------------KVVRKQSQKLRVGDIVQVKENETFPCDLILLSTSREDGTCFVTTASLDGESSHKTYYAVQDT-KAFSTAEEVDTLHATIECEQPQPDLYKFVGRINIYLDRDEP-----IARPLGSENLLLRGATLKNTEYIHAVAIYTGMETKMALNYQSKSQKRSAVEKSMNAYLIVYLCILISKALINTVLKYVWQADPNRDEPWYNQRTESERQRHVLIRAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFILWDDDMFDEEVGERPLVNTSDLNEELGQVEYVFTDKTGTLTENNMELRECCVDGHVYVP---HAICNGQILPG-------------AAGMDMIDSSPG-------------VEGKEREELFFRALCLCHTVQVKEE-------------------------ETVDGIKRGIHQGKATSF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YISSSPDEVALVEGMKRLGFTYLRLKDSHMEILNRED-----------EMERFELLDVLNFDSVRRRMSVIVRSNS--GEYYLFCKGADSSVFPRVVSG---------------------------------------------------------------------------------------------------------------------------------------------------------------------KVEQVRARVEHNAVEGLRTLCVAYKRLSQEEYEETCRLLTSAKLALQERDKKLAEAYDVIEKDFILLGATAVEDRLQDKAADTIESLHKAGIKVWVLTGDKMETAAATCYASKLFHRNTQILELTTKRTEEQ------SLHDVLFDLSRTVLRQHGSMTRDTFSGLSGDYQDYGLIIDGATLSAVLKPTQDATSNSGNYKEIFLEICRNCSAVLCCRMAPLQKAQIVKLIKASKEHPITLAIGDGANDVSMILEAHVGIGIMGKEGRQAARNSDYAITKFKHLKKMLLVHGHYYYIRIAELVQYFFYKNVCFIFPQFLYQFFCGFSQQPLYDTAYLTLYNISFTSLPILLYSLMEQHINMDILKRDPSLYRDIAKNSLLTWPTFIYWTFLGVFDAVVFFFGAFFLF-DNTTFTSNGQLMATNTQMMFGNWTFGTLVFTVLVFTVTLK-LALDTHYWTWINHFVIWGSLLFYVIFSLLWGGIIWPFLNYQRMYYVFMQMLSSGPAWLSIILLIIVSLLPDVLKKVLCRALWPTTTERIQNADKLYKGHLSEFSPLTSLHAPPARKHERRGNERQNHAHRRSDSSPTKKLMCTYWGGKPDYCTFSSFLRIGENPRFSGAAYAYSAPGPETSV------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6DFW5-1", "uniprot_id": "AT11B_MOUSE", "id": "Q6DFW5-1", "name": "Phospholipid-transporting ATPase IF", "aln": "----------------------------------------------------------------------------------------MWRWVRQQLGFDPPH------------------QSDTRTIYIAN--RFPQNG---LYTPQKFIDNRIISSKYTIWNFVPKNLFEQFRRVANFYFLIIFLVQLMIDTPTS-PITSGLPLFFVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSG--------------------------------------------------------------GLVKTRSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVSVPET-AVLQTVANLDSLIAVIECQQPEADLYRFMGRMIIT-QQMEE-----IVRPLGPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLIILISEAIISTILKYTWQAEEKWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGLKYQEINGKLVPEGPSPDSTEGE-----VPFLGSLSHLSNSAHLTATS-LRTSPESETELIKEHDLFFKAVSLCHTVQISNVQ----------------------TDGIGDGP-WQPNLAPAQLE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YYASSPDEKALVEAAARAGIIFVGISEETMEVKVLG------------RLERYKLLHILEFDSDRRRMSVIVQAPS--GEKLLFAKGAESSILPKCIGG---------------------------------------------------------------------------------------------------------------------------------------------------------------------EIAKTRIHVDEFALKGLRTLCIAYRQFTAKEYEDVDRRLFEARTALQHREEKLADAFQYIEKDLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELINQKSDSG-------CAEQLRQLARRITEDHV--------------IQHGLVVDGTSLSLALR----------EHEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPVLIYSLVEQHIDPHVLQSKPTLYRDISKNGLLSIKAFLYWTVLGFSHAFIFFFGSYFLVGKDTSLLGNGQ--------MFGNWTFGTLVFTVMVITVTVK-MALETHFWTWINHLVTWGSIIFYFIFSLFYGGILWPFLGSQNMYFVFIQLLSSGSAWFAILLMVVTCLFIDVVKKVFDRQLHPTSTEKAQLAEAHSSVKCLDSVCCFP-GETPCASVGR--------MLERVIGRCSPNHISRLWNASDPFYTNDRSILTLSPMDSSTC-------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0KX31-1", "uniprot_id": "A0ABK0KX31_RAT", "id": "A0ABK0KX31-1", "name": "Phospholipid-transporting ATPase", "aln": "----------------------------------------------------------------------------------------MWRWVRQQLGFDPPH------------------QSDTRTIYIAN--RFPQNG---LYTPQKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMIDTPTS-PITSGLPLFFVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSG--------------------------------------------------------------GLVKTRSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVSVPET-AVLQTVANLDSLIAVIECQQPEADLYRFMGRMIIT-QQMEE-----IVRPLGPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLIILISEAIISTILKYTWQAEEKWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGLKYQEINGKLVPEGPSPDSAEGN-----DPYLGSLSHLSSSAHLTATS-LRTSPESETELIKEHDLFFKAVSLCHTVQISNVQ----------------------TDGIGDGP-WQPNLAPTQLE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YYASSPDEKALVEAAARAGIIFIGISEETMEVKVLG------------RVERYKLLHILEFDSDRRRMSVIVQAPS--GEKLLFAKGAESSILPKCIGG---------------------------------------------------------------------------------------------------------------------------------------------------------------------EIAKTRIHVDEFALKGLRTLCIAYRQFTAEEYEDVNRRLFEARTSLQRREEKLAGVFQYIEKDLVLLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELINQKSDSG-------CAEQLRQLARRITEDHV--------------IQHGLVVDGTSLSLALR----------EHEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAARNSDYAVARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPVLIYSLLEQHIDPHVLQSKPTLYRDISKNRLLSMKAFLYWTVLGFSHAFIFFFGSYFLIGKDTSLLGNGQ--------MFGNWTFGTLVFTVMVITVTVK-MALETHFWTWINHLVTWGSIIFYFIFSLFYGGILWPFLGSQNMYSVFIQLLSSGSAWFAILLMVVSCLFVDVVKKVFDRQLHPTSTQKAQLAEAPSGVKCLDSICCFP-GETPCASVGR--------VLDRVIGRCSPNHISRLWSASDPFYTNDRSILTLSPMDSSTC-------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2G3-1", "uniprot_id": "AT11B_HUMAN", "id": "Q9Y2G3-1", "name": "Phospholipid-transporting ATPase IF", "aln": "----------------------------------------------------------------------------------------MWRWIRQQLGFDPPH------------------QSDTRTIYVAN--RFPQNG---LYTPQKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMIDTPTS-PVTSGLPLFFVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSG--------------------------------------------------------------GLVKTRSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPET-ALLQTVANLDTLVAVIECQQPEADLYRFMGRMIIT-QQMEE-----IVRPLGPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEEKWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEINGRLVPEGPTPDSSEGN-----LSYLSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTVQISNVQ----------------------TDCTGDGP-WQSNLAPSQLE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YYASSPDEKALVEAAARIGIVFIGNSEETMEVKTLG------------KLERYKLLHILEFDSDRRRMSVIVQAPS--GEKLLFAKGAESSILPKCIGG---------------------------------------------------------------------------------------------------------------------------------------------------------------------EIEKTRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELINQKSDSE-------CAEQLRQLARRITEDHV--------------IQHGLVVDGTSLSLALR----------EHEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDISKNRLLSIKTFLYWTILGFSHAFIFFFGSYLLIGKDTSLLGNGQ--------MFGNWTFGTLVFTVMVITVTVK-MALETHFWTWINHLVTWGSIIFYFVFSLFYGGILWPFLGSQNMYFVFIQLLSSGSAWFAIILMVVTCLFLDIIKKVFDRHLHPTSTEKAQLTETNAGIKCLDSMCCFPEGEAACASVGR--------MLERVIGRCSPTHISRSWSASDPFYTNDRSILTLSTMDSSTC-------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXG7-1", "uniprot_id": "Q9VXG7_DROME", "id": "Q9VXG7-1", "name": "Phospholipid-transporting ATPase", "aln": "------------------------------------------------------------------------------------------------MGADKKK--------------------------SADPLRIQIGG---IESRQQKPLNRVTTTKYTWFTFLPLNFYEQFRRAVYFYFLIITIVSFFVNETIS-PLVSLLPLLFVMIITALKEGLEDYSRSKSDKLVNTARVTVIRNG--------------------------------------------------------------KEEIINSQFIVPGDLVVVRNDGDVPCDLVLLQSSSADRKCFVNTANLDGETNLKTICVPTNY-LLAGDHELQG--KDCIVCEPSSADLYTFNGRLELRSGNDGAGSSAGDALPLTIDNLLLRGVRVKSTERVVGCAIYTGMHTKLQLNSRYTGNKSASSEKYINRFMVALIVGMIVVVVVLYLIERHKEAKIVPTMPYQGPPTN----FNSAWQIFEDFLSFLLLFNYMVPISAYMNIEVYRIFGMHFMHNDLHLYDEETDQPCRVNASNLNEELGQVNILFSDKTGTLTKNLMKFVNCYVPGTNYQLQNTHLVSEGT-----------------DEKFELEKLDAD-------------------AAVLFEALAVCHTVEVLQ-------------------EVGDKTLESSESVSEQSHLMSRN------------------------------------------------IVDR-------------------------------------------------------------------------------------------------------------------------------------------YQASSPDEKALLEGCASLGLVYEGQENDVLSICRYP----------SAEKVQFKRLHVLEFSSERQRMSVIVRDQS--DTIWLYSKGAESAIFPRCKAS--------------------------------------------------------------------------------------------------------------------------------------------------------------------PLVEQTDAQITKYAQNGLRTMAVGRRMLTDDELFHFEELYRKANTQLSNRNELIASCYETVENELDLLGATALEDALQEHVGETLEALQAAGLKIWVLTGDKVETAYNIGLACRHIPRGSKQHFIINTTEPAE-------LLARLD------MIGDD--------------EPEVLIVDGTTITALLE----------HTPRQFADLALRCRAVLCCRLSPLQKSEIVTLIKR-RKKYITAAIGDGANDVSMIQEAHIGIGITGREGKQAARCADFSIARFEMLRRLFLVHGHYNSQRLAFLVLFYCYKNIIITGCMALYQVYDLYSATNVYNSIYLWLFDIVYISFSFTVLAICDKDYSEETLLSHPELYKPLAHNRQASMGVFSLWILNGFVQCFIIFFFTYAMLNDANVLFNGGQ--------TASFQTFGTMLITIIVIVGNLK-LLLVAHYMTYRNFAMILASIAAFMLTTYLY-----NLYTSGELYDVYNQFLSSLPIWLFTIICSVACLLPDFVIKVVN-----------------------------------DMYRK---------VPLKSKPVV----------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VXG6-1", "uniprot_id": "Q9VXG6_DROME", "id": "Q9VXG6-1", "name": "Phospholipid-transporting ATPase", "aln": "-------------------------------------------------------------------------------MNFFGHDHLSGFRRIDRLGAHRQTPWADQESFHLKDAFLWNWHKGSRVSTINDWLQIQIGGPQDIKKKRPKGQNRIKSTKYTLITFLPQNLLEQFRRIANFYFLVMTIISLLIDSPVS-PMTSLLPLVFVIAVTAAKQGYEDILRYRTDNVVNSSPVTVIRDG--------------------------------------------------------------KEAIIKSQDVIPGELIVVERDCDVPCDLVLLRSTDPHGKCFITTANLDGESNLKTLMVPRDL-PTVDLPEMHK--LGIIECESPTTDLYSFNGKIELKGGE-------GRVLPLSTENVLLRGSRVKNTECVIGCAVYTGMISKLQLNSRLTRNKNASSETYINRFLIVILVALIAIVTLLYFLKRYNELFVIPKLTYLGDATD----SYSVKQFLQDYLSFLILFNYLIPISLYVTIELQRVIGSWFMEWDLELYENETDQPCVVNTSNLNEELGQINILFSDKTGTLTKNEMNFQQCSINGNKFLFKKTRLEDEET-----------------KALLDINKFSAN-------------------QRVFFQALSICHTVQVASGSLEQADAGTAKREPVTAIKSGPPEMYSISDITEESHNASQQSELNVGHTIDNSVSAHPNGVNSTIISSDVNPLLVSDDGYGVERRKRPVVIKRSPNFARSNRMNNGAASDLNINQTDPNTVTNGVEPTTNFRPISLQFRRSTSEKDLQQSWEAPSGQAPGHRRAHSYGAPNAYLTNPVTASTPPAGVLFRSPSTTSRESYAAPTFTRQPTILVRAESQRRKNEIRDFIFTLDYQASSPDEKALVEACANLGMVYTGDDDETLRVRIVPPHMDYKRPFAKPREETFQRLHVLEFTSDRKRMSVIVRDTD--GKKWIYTKGAESYVFPLCANSSA------------------------------------------------------------------------------------------------------------------------------------------------------------------ELVTKTDAHISDFARLGLRTLAIARRLISEEEYQDFLVELAQANSSLENRKQLSEECYAKIESNLDLLGATAVEDALQDDVADTLVSLQAAGIKIWVLTGDKVETALNIALSCGHIPPDAKKYFIMECKNREE-------MLLHLNALDREIIFGIG--------------QECALLIDGKSLGVALA----------EASSEFRDVAVKCTAVLCCRLSPLQKSEVVSLIKSSNENYNTASIGDGANDVSMIQEAHVGIGIMGREGRQAARCADFAFAKFCMLKRLLLVHGHYHSVRLSLLVLYFFYKNIVFMGIMFLFQFHTLFSSSSVYDSLFLTLYNVIYTSLPILFIAISEKPYTEEKLMRTPQLYKKNTDNKQLHWPYFLMWVLFAIYHSVIIFYFAFCFFYYNNVLLNYGQ--------TVAFSCFGTLLMWTVVVVVNLK-LWLESMYLSFWYIFTIIISILGFVVTTVIYN--VINLDYDTDIYWAYNNLLASLPVWLWIIVTCVACLVPDYTIRMLQRALNIKSF-----------------------SIFPGKQRK---------LKMREKFESTYL-------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12674-1", "uniprot_id": "ATC8_YEAST", "id": "Q12674-1", "name": "Probable phospholipid-transporting ATPase DNF3", "aln": "MGIADGQRRRSSSLRTQMFNKHLYDKYRGRTDDEIELEDINESKTFSGSDNNDKDDRDETSGNYAAEEDYEMEEYGSPDVSYSIITKILDTILDRRRTFHSKDGR------------HIPIILDHNAIEYKQAATKRDGHLIDERFNKPYCDNRITSSRYTFYSFLPRQLYAQFSKLANTYFFIVAVLQMIPGWSTTGTYTTIIPLCVFMGISMTREAWDDFRRHRLDKEENNKPVGVLVKDGNNDAQEVYTLPSSVVSSTAYLTKSAAAENNPPLNDDRNSSQGHFLDTHFNNFELLKNKYNVHIHQKKWEKLRVGDFVLLTQDDWVPADLLLLTCDGENSECFVETMALDGETNLKSKQPHPELNKLTKAASGLANINAQVTVEDPNIDLYNFEGNLELKNHRNDT----IMKYPLGPDNVIYRGSILRNTQNVVGMVIFSGEETKIRMNALKNPRTKAPKLQRKINMIIVFMVFVVATISLFSYLGHVLHKKKYIDQ------NKAWYLFQADAGVAPTIMSFIIMYNTVIPLSLYVTMEIIKVVQSKMMEWDIDMYHAETNTPCESRTATILEELGQVSYIFSDKTGTLTDNKMIFRKFSLCGSSWLHNVDLGNSEDNFEDNRDNTNSLRLPPKAHNGSSIDVVSIGDQNVLDRLGFSDAPIEKGHRPSLDNFPKSRNSIEYKGNSSAIYTGRPSMRSLFGKDNSHLSKQASVISPSETFSENIKSSFDLIQFIQRYPTALFSQKAKFFFLSLALCHSCLPKKTHN----------------------------------------------------------------------------------------------------------------------------------------------ESIGEDSIEYQSSSPDELALVTAARDLGYIVLNRNAQILTIKTFPDGFDG-----EAKLENYEILNYIDFNSQRKRMSVLVRMPNQPNQVLLICKGADNVIMERLHDRELAAKKMADICTSTKERKDAEAELVLQQRKSLERMVDEEAMARTSLRNSLSSVPRASLSLQAVRKSLSMKNSRTRDPEKQIDSIDQFLETVKKSDQEIGSVVNKSRKSLHKQQIEKYGPRISIDGTHFPNNNVPIDTRKEGLQHDYDTEILEHIGSDELILNEEYVIERTLQAIDEFSTEGLRTLVYAYKWIDIGQYENWNKRYHQAKTSLTDRKIKVDEAGAEIEDGLNLLGVTAIEDKLQDGVSEAIEKIRRAGIKMWMLTGDKRETAINIGYSCMLIKDYSTVVILTTTDEN---------IISKMNAVSQEVDSGNI--------------AHCVVVIDGATMAMFEGNP--------TYMSVFVELCTKTDSVICCRASPSQKALMVSNIRNTDPNLVTLAIGDGANDIAMIQSADIGVGIAGKEGLQASRVSDYSIGQFRFLLKLLFVHGRYNYIRTSKFMLCTFYKEITFYFTQLIYQRYTMFSGSSLYEPWSLSMFNTLFTSLPVLCIGMFEKDLKPMTLLTVPELYSYGRLSQGFNWLIFMEWVILATTNSLIITFLNVVMWGMSSLSDNTMY-------------PLGLINFTAIVALINVKSQFVEMHNRNWLAFTSVVLSCGGWLVWCCALPILNNTDQIYDVAYGFYNHFGKDITFWCTSLVLALLPITLDIVYKTFKVMIWPSDSDIFAELEQKSDIRKKLELGAYSEMRQGWTWDKDPSTFTRYTDKVLSRPRTNSRASAKTHNSSIYSMSNGNVDHSSKKNFFGNSSKKSSERYEVLPSGKLIKRPSLKTQSSKDSIGGNITTKLTKKLKLPSRNVEDEDVNQIIQARLKDLE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **: :::** .*:* :: ** : . **::: ::.. . . : . .: :** ..: :: ::. :* * . *. * * .: . . : *:.: : : .*.**::* . *.: * ****:. *: : : : . *** * *.: : .* :.:: :* ::.*: : . .:::* :*: :* . .. :. :: : :: : : . .. ::*::::* ::*:* *:.:*: :.. :: * .::. * .:: : *****:. :*:*******.* * : : : * : : : . :::: : :***** **: . * : : :: *. : * . *:****:*: . : ***:. :: : : : * **: . : : : *. * *. :* : *:*.**:** **: . ::: :: **:*:*:***** *** :. : : : .::** :: * ::. :*:*** :* **: :: :: * ::******::** .:.:*:*: *:** ** * :*::. :: * ::::.**: * : :: **:: : ::* . :* :*:. * ::: : *:.. .: :: * . ** . * * . . . :: : . * : : :* .:* : .: * :. * : : . . * :: : : . ", "identical_positions": 160, "similar_positions": 280, "identity": "8.56%" }, { "cls_id": "homologset.agr.SGD:S000004775", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYB4-1", "uniprot_id": "D3ZYB4_RAT", "id": "D3ZYB4-1", "name": "phosphatidate phosphatase", "aln": "------------------------------------------------MNYVGQLAGQVLVTVKELYKGINQATLSGCIDVVVVRQQDGSYQCSPFHVRFGKLGVLRSKEKVIDIEINGSAVDLHMKLGDNGEAFFVEETEEEYEKLPAYLATSPIPTEDQFFKHIDPPLVKSSGNERPPQSSDVSHTLESEAVFTPSSVKKKKRRRKKCKQDNRKEEQ------AASPVAEDVGDVAVSSDDEKRAQAARGSSNASLK-------EEDYKEPPPFHSGDNYPLSDGDWSPLET----------------------------------SYPQTVCPKSDSELEVKPSESLLRSE-SHMEWTWGGFPESTKVSKRERYDYHPRTA------------------TITPSENTHFRVIPSEDS---------------------LIREVEKDATVEDT------------------------------------------------------TCTIVKPKPRALCKQLSDAAS-TELPES----------PLEAPQI----------SSTLDADPVP-SPSAEAPSE---PKPAAKVDSPTKRKGVHKRSQHQGPDDIYLDDLKALEPEVAALYFPKSDTDPG-SRQWPESDT--FSGSQSPQSVGSAAADSGTECLSDSAMDLPD-VTLSLCGGLSENGEISKEKFMEHIITYHEFAENPGLIDNPNLVIRIYNRYYNWALAAPMILSLQVFQKSLPK--------------------------ATVESWVKDKMPKKSGRWWF-WRKK-ESMTKQLPETKEGKSEVPPANDLPSGTEEPVSARPAEN-DTSSDEGSQELEETIKVDP--ISMETLSHCGTASYKKSLRLSSDQIAK-LKLHDGPNDVVFSITTQYQGTCRCAGTIYLWNWNDKVIISDIDGTITKSDALGQILPQLGKDWTHQGIARLYHSINENGYKFLYCSARAIGMADMTRGYLHWVNDKGTILPRGPLMLSPSSLFSAFHR----EVIEKKPEKFKIECLNDIKNLFAPSRQPFYAAFGNRPNDVYAYTQVGVPDCRIFTVNPKGELIQERTKGNKSSYHRLSELVEHVFPLLNKEQNSAFPCP-EFSSFCYWRDPIPDVDLDDLA-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PI5-1", "uniprot_id": "LPIN2_MOUSE", "id": "Q99PI5-1", "name": "Phosphatidate phosphatase LPIN2", "aln": "------------------------------------------------MNYVGQLAGQVLVTVKELYKGINQATLSGCIDVVVVRQQDGSYQCSPFHVRFGKLGVLRSKEKVIDIEINGSAVDLHMKLGDNGEAFFVEETEEEYEKLPAYLATSPIPTEDQFFKHIETPLVKSSGNERPAQSSDVSHTLESEAVFTQSSVKKKKRRRKKCKQDNRKEEQ------AASPVAEDVGDVGVSSDDEKRAQAARGSSNASLK-------EEDYKEPSLFHSGDNYPLSDGDWSPLET----------------------------------TYPQAVCPKSDSELEVKPSESLLRSE-PHMEWTWGGFPESTKVTKRERYDYHPRTA------------------TITPSENTHFRVIPSEDS---------------------LIREVEKDATVEDT------------------------------------------------------TCTIVKPKPRALCKQLSDAAS-TELPES----------PLEAPQI----------SSLLDADPVP-SPSAEAPSE---PKPAAK-DSPTKKKGVHKRSQHQGPDDIYLDDLKALEPEVAALYFPKSDTDPG-SRQWPESDT--FSGSQSPQSVGSAAADSGTECLSDSAMDLPD-VTLSLCGGLSENGEISKEKFMEHIITYHEFAENPGLIDNPNLVIRIYNRYYNWALAAPMILSLQVFQKSLPK--------------------------ATVESWVKDKMPKKSGRWWF-WRKK-ESMIKQLPETKEGKSEVPPANDLPSNAEEPTSARPAEN-DTSSDEGSQELEESIKVDP--ITVETLSHCGTASYKKSLRLSSDQIAK-LKLHDGPNDVVFSITTQYQGTCRCAGTIYLWNWNDKVIISDIDGTITKSDALGQILPQLGKDWTHQGIARLYHSINENGYKFLYCSARAIGMADMTRGYLHWVNDKGTILPRGPLMLSPSSLFSAFHR----EVIEKKPEKFKIECLNDIKNLFAPSRQPFYAAFGNRPNDVYAYTQVGVPDCRIFTVNPKGELIQERTKGNKSSYHRLSELVEHVFPLLSKEQNSAFPCP-EFSSFCYWRDPIPDLDLDDLA-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92539-1", "uniprot_id": "LPIN2_HUMAN", "id": "Q92539-1", "name": "Phosphatidate phosphatase LPIN2", "aln": "------------------------------------------------MNYVGQLAGQVIVTVKELYKGINQATLSGCIDVIVVQQQDGSYQCSPFHVRFGKLGVLRSKEKVIDIEINGSAVDLHMKLGDNGEAFFVEETEEEYEKLPAYLATSPIPTEDQFFKDIDTPLVKSGGDETPSQSSDISHVLETETIFTPSSVKKKKRRRKKYKQDSKKEEQ------AASAAAEDTCDVGVSSDDDKGAQAARGSSNASLK-------EEECKEPLLFHSGDHYPLSDGDWSPLET----------------------------------TYPQTACPKSDSELEVKPAESLLRSE-SHMEWTWGGFPESTKVSKRERSDHHPRTA------------------TITPSENTHFRVIPSEDN---------------------LISEVEKDASMEDT------------------------------------------------------VCTIVKPKPRALGTQMSDPTSVAELLEP----------PLESTQI----------SSMLDADHLPNAALAEAPSE---SKPAAKVDSPSKKKGVHKRSQHQGPDDIYLDDLKGLEPEVAALYFPKSESEPG-SRQWPESDT--LSGSQSPQSVGSAAADSGTECLSDSAMDLPD-VTLSLCGGLSENGEISKEKFMEHIITYHEFAENPGLIDNPNLVIRIYNRYYNWALAAPMILSLQVFQKSLPK--------------------------ATVESWVKDKMPKKSGRWWF-WRKR-ESMTKQLPESKEGKSEAPPASDLPSSSKEPAGARPAEN-DSSSDEGSQELEESITVDP--IPTEPLSHGSTTSYKKSLRLSSDQIAK-LKLHDGPNDVVFSITTQYQGTCRCAGTIYLWNWNDKIIISDIDGTITKSDALGQILPQLGKDWTHQGIAKLYHSINENGYKFLYCSARAIGMADMTRGYLHWVNDKGTILPRGPLMLSPSSLFSAFHR----EVIEKKPEKFKIECLNDIKNLFAPSKQPFYAAFGNRPNDVYAYTQVGVPDCRIFTVNPKGELIQERTKGNKSSYHRLSELVEHVFPLLSKEQNSAFPCP-EFSSFCYWRDPIPEVDLDDLS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BAN1-1", "uniprot_id": "A0A8M2BAN1_DANRE", "id": "A0A8M2BAN1-1", "name": "phosphatidate phosphatase", "aln": "-----------MKRLHSRTEAETTGTEEDNSEQDESSSLRASWSWSDTMNYVGQLAGQVLVTMKELYKGINQATLSGCIDVVVVRQKDGTYQCSPFHVRFGKLGVLRSKEKVIDIEINGEPVDLHMKLGDNGEAFFVQETEEQNEIVPAHLATSPIPTESHLFWIGGDHRSSQNLDDDPLDPEDP----PDRPVASTGGAKKKKKRRKKHKGDPRREEFTPPAVISSTPSTDEIFEMDLSSDED-AISNTRSSSVSTVK-------ESEPKLPTIRHSLDSYPYSDGDWSPSDSH---------------------------------AMSEAFSPKSDSELVVRPSESLLKME-SHMQWTWGEFPESTRVSKKEK-IELPKTV------------------TITPSENTHFRVILSSEA---------------------METD-EREPTSGTP------------------------------------------------------SCTIVKPEPRTPVTPKTPTESELETMPC----------EVLTSTP----------SDILTAAPTSPAAVSAAPLGGDIGDVGSKTDSPSKKKGVPKRSQHQGPEDIYLDDLNVLEPDVAARYFPKSDSDAG-SKHWMDSGM--HSGSQSPQSVGSAAADSGTECLSDSASDLPD-VTLSLCGGLSENGEISKEKFMEHIITYNEFAENPAIIDNQNLVVKIGNRYYNWTLAAPLILSLQAFQKNLPK--------------------------ATEEAWVKERMPKKSGRWWF-WRKRADSTIKQSESTGKLEAKQSQLEEGSSSLSMESHARKVDTRDSSSDEEGKEVSAAASSMERKIQSEPHGHTSTHSYRKSLRLSSSQIAS-LKLKEGPNDVMFSITTQYQGTCRCEGTIYLWNWDDKVIISDIDGTITKSDVFGQILPQFGKDWTHQGIAKLYHSVAENGYKFLYCSARAIGMADMTRGYLQWVNDGGIILPRGPLMLSPSSLFSAFHR----EVIEKKPEIFKIECLTDIKNLFLPNKHPFYAAFGNRTNDVFAYKEVGVPVCRIFTVNPKGELIQEQTKGNKSSYSRLSELVDHVFPLLSKEQSSAFSFP-EFSTFCFWRQPIPEIRPEDLLL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q91ZP3-1", "uniprot_id": "LPIN1_MOUSE", "id": "Q91ZP3-1", "name": "Phosphatidate phosphatase LPIN1", "aln": "------------------------------------------------MNYVGQLAGQVFVTVKELYKGLNPATLSGCIDIIVIRQPNGSLQCSPFHVRFGKMGVLRSREKVVDIEINGESVDLHMKLGDNGEAFFVQETDNDQEIIPMYLATSPILSEGAARMESQLKRNSVDRIRCLDPTTAAQGLPPSDTPSTGSLGKKRRKRRRKAQLDNLKRDDN-----VNSSEDEDMFPIEMSSDEDTAPMDGSRTLPNDVPPFQDDIPKENFPSISTHPQSASYPSSDREWSPSPSSLVDCQRTPPHLAEGVLSSSCPLQSCHFHASESPSGSRPSTPKSDSELVSKSADRLTPKNNLEMLWLWGELPQAAKSSSPHKMKESSPLG------------------SRKTPDKMNFQAIHSES-----------------------------SDTFSDQ------------------------------------------------------SPTMARGLLIHQSKAQTEMQFVNEEDLE----------SLGAAAP----------PSPVAEELKAPYPNTAQSSS--------KTDSPSRKK--DKRSRHLGADGVYLDDLTDMDPEVAALYFPKNGDPGGLPKQASDNGA--RSANQSPQSVGGSGIDSGVESTSDSLRDLPS-IAISLCGGLSDHREITKDAFLEQAVSYQQFADNPAIIDDPNLVVKVGNKYYNWTTAAPLLLAMQAFQKPLPK--------------------------ATVESIMRDKMPKKGGRWWFSWRGRNATIKEESKPEQCLTGKGHNTGEQPAQLGLATRIKHESS---SSDE---EHAAAKPSGS--SHLS---LLSNVSYKKTLRLTSEQLKS-LKLKNGPNDVVFSVTTQYQGTCRCEGTIYLWNWDDKVIISDIDGTITRSDTLGHILPTLGKDWTHQGIAKLYHKVSQNGYKFLYCSARAIGMADMTRGYLHWVNERGTVLPQGPLLLSPSSLFSALHR----EVIEKKPEKFKVQCLTDIKNLFFPNTEPFYAAFGNRPADVYSYKQVGVSLNRIFTVNPKGELVQEHAKTNISSYVRLCEVVDHVFPLLKRSHSCDFPCSDTFSNFTFWREPLPPFENQDMHSASA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FDH2-1", "uniprot_id": "F7FDH2_RAT", "id": "F7FDH2-1", "name": "phosphatidate phosphatase", "aln": "---------------------------MEEKWSPHRRRGFLQATKVQTMNYVGQLAGQVFVTVKELYKGLNPATLSGCIDIIVVRQPNGSLQCSPFHVRFGKMGVLRSREKVVDIEINGESVDLHMKLGDNGEAFFVQETDNDQEVIPMYLATSPILSEGASRMESQLKRNSVDRIRGLDPTTAAQGLPPSDTPSTGSLGKKRRKRRRKAHLDNLKRDDN-----VNTSEDEDMFPIEMSSDEDTALMDGSRALPNDVPPFQDDIPKENLPSISTYPQSASYPNSDREWSPSPSSLVDCQRTPPHLAEGVLSSSCPLQSCHFHASESPSGSRPSTPKSDSELVSKSADRLTPKNNLEMLWLWGELPQAAKSSSPHKMKDSSPLG------------------GRKMADKIHFQTIHSES-----------------------------SDTFSDQ------------------------------------------------------SPTMARGLLIHQSKAQTEMQFVNEEDLE----------ALGAAAP----------PLSVAEELKAPASSTAQTSS--------KSDSPSRKK--DKRSRHLGADGVYLDDLTDMDPEVAALYFPKNGDPGGLPKQASDNGA--RSANQSPQSVGSSGIDSGVESTSDSLRDLPS-IAISLCGGLSDHREITKDAFLEQAVSYQQFADNPAIIDDPNLVVKIGNKYYNWTTAAPLLLAMQAFQKPLPKSSCLSYLHMILDAIRFCLSKIFSPPTATVESIMRDKMPKKGGRWWFSWRGRNATIKEESKPEQGLPGKGHNTGEQPAQLGLTTRIKHESS---SSDE---EHSATKPSSS--SHLS---LLSNVSYKKTLRLTSEQLKS-LKLKNGPNDVVFSVTTQYQGTCRCEGTIYLWNWDDKVIISDIDGTITRSDTLGHILPTLGKDWTHQGIAKLYHKVSQNGYKFLYCSARAIGMADMTRGYLHWVNERGTVLPQGPLLLSPSSLFSALHR----EVIEKKPEKFKVQCLTDIKNLFFPNTEPFYAAFGNRPADVYSYKQVGVSLNRIFTVNPKGELVQEHAKTNISSYVRLCEVVDHVFPLLKRSHSCDFPCSDTFSNFTFWREPLPPFENQDVHSASA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14693-1", "uniprot_id": "LPIN1_HUMAN", "id": "Q14693-1", "name": "Phosphatidate phosphatase LPIN1", "aln": "------------------------------------------------MNYVGQLAGQVFVTVKELYKGLNPATLSGCIDIIVIRQPNGNLQCSPFHVRFGKMGVLRSREKVVDIEINGESVDLHMKLGDNGEAFFVQETDNDQEVIPMHLATSPILSEGASRMECQLKRGSVDRMRGLDPSTPAQVIAPSETPSSSSVVKKRRKRRRKSQLDSLKRDDN-----MNTSEDEDMFPIEMSSDEAMELLESSRTLPNDIPPFQDDIPEENLSLAVIYPQSASYPNSDREWSPTPS---------------------------------PSGSRPSTPKSDSELVSKSTERTGQKN-PEMLWLWGELPQAAKSSSPHKMKESSPLS------------------SRKICDKSHFQAIHSES-----------------------------SDTFSDQ------------------------------------------------------SPTLVGGALLDQNKPQTEMQFVNEEDLE----------TLGAAAP----------LLPMIEELKPPSASVVQTAN--------KTDSPSRKR--DKRSRHLGADGVYLDDLTDMDPEVAALYFPKNGDPSGLAKHASDNGA--RSANQSPQSVGSSGVDSGVESTSDGLRDLPS-IAISLCGGLSDHREITKDAFLEQAVSYQQFVDNPAIIDDPNLVVKIGSKYYNWTTAAPLLLAMQAFQKPLPK--------------------------ATVESIMRDKMPKKGGRWWFSWRGRNTTIKEESKPEQCLAGKAHSTGEQPPQLSLATRVKHESS---SSDE---ERAAAKPSNA--GHLP---LLPNVSYKKTLRLTSEQLKS-LKLKNGPNDVVFSVTTQYQGTCRCEGTIYLWNWDDKVIISDIDGTITRSDTLGHILPTLGKDWTHQGIAKLYHKVSQNGYKFLYCSARAIGMADMTRGYLHWVNERGTVLPQGPLLLSPSSLFSALHR----EVIEKKPEKFKVQCLTDIKNLFFPNTEPFYAAFGNRPADVYSYKQVGVSLNRIFTVNPKGELVQEHAKTNISSYVRLCEVVDHVFPLLKRSHSSDFPCSDTFSNFTFWREPLPPFENQDIHSASA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P333-1", "uniprot_id": "A0A8M9P333_DANRE", "id": "A0A8M9P333-1", "name": "phosphatidate phosphatase", "aln": "MQREDEEIENDTKSELKVQTEEEEEEEEEEEEDEEDEAITSSWSWTQTMNYVGQLAGQVFVQVKELYRGLNPATLSGCIDVIVVRQPDGALVCSPFHVRFGKMGVLRSREKVVDIEINGEPVNLHMKLGENGEAFFVKETEDDQEVIPPYLATSPIPSDGGVMMG---------------------------SSNENSLMKKRRKRRKKCRMEGVKREES-----VEFS-DEELFNMDINSSE---QSDQNRDLSSGG-------------SSTGNKPNTSYAHSDGDWSPVHS---------------------------------LNASRPCSPKSDSELLCKKHQ-----EDSAMSWSWGELPQTAKPSFLPAKPTALPSCPL----------------SIPVSDNTHFRVITESD-----------------------------THQHHRN------------------------------------------------------RTLYADG------------QTNAEKECE----------KQHMIRR----------ASVMSETEVGGANTGPRPQN--------KTESSLKRK--DKKSRHLGSDGVYLDDIKDLEPEVAALYFPKSG--------SERYGE--DRVTVSPQSMCSSGADSGVDS-----YDLPS-MAISLCGGLTENRDITKEHFQQKSVSFQQFSDNPSIINDPNLVVKIGSKYYNWSTAAPIMLAMQAFQKPLPK--------------------------ATVERLTKEKMPRNRGRWWFSWRGRTSSSKQDLTS----GGSACAAGDE----NIKNRRKEESS---SSDE---DLSAKQTPAA--VTIDSAPLGGGVTYQKTLRLSSEQLVS-LQLKDGANDVVFSVTTQYQGTCRCEGTIYLWNWDDKIIISDIDGTITRSDKLGHILPTLGKDWTHQGIAHLYHNVSQNGYKFLYCSARAIGMADMTRGYLHWVNERGTMLPQGPVLLSPSSLFSALHR----EVIEKRPEKFKVACLTDIRNLFLPNTEPFYAAFGNRDTDVLSYKEVGVPLNRIFTVNPKGELIQEHAKTNISSYVRLGEVVDHVFPLLKRSSSSDFPCSDTFSQFTFWREQLPLLDGQIANTINTT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q99PI4-1", "uniprot_id": "LPIN3_MOUSE", "id": "Q99PI4-1", "name": "Phosphatidate phosphatase LPIN3", "aln": "------------------------------------------------MNYVGQLAETVFGTVKELYRGLNPATLSGGIDVLVVRQRDGSFRCSPFHVRFGKLGVLRSREKVVDIEINGEPVDLHMKLGDSGEAFFVQELDSDEEDVPPRLCTSPIPWGG-LSGFPSDSQIGTA---------------SEPEGLVIT-----GRRKRRRRRKPRRREE------DAVDSSSEELEAGAESELTLLEKPTPESPSAQEA------------EEPSSQPKDIHPYSDGECTPQAN---------------------------------LSSGDLMSPKSDSELELRSLEPSPLRAESHMQWVWGRLPKVAKAERPEF--------------------------SLILESMAEAICALPEEP------------------SPSSSPSEAGVDTLSPP-----------------------------------------------------VLHPGVRADTFHPAVEAHCEETAVDS-------------PLAAPESKETK------TQNSRGAGHPPATKSWSWTTPESHTPSGHP-QVSRGKGSLKRNQHLGPSDIYLDDLPSLDSENVALYFPKSEYGMGARRWSE------PSNQKLLE-------SPNPEHIAECTLDSVDKIELSLCGGLADNRDISLEKFTQHMVSYEDLTKNPGLLDDPNLVVKINEKHYNWAVAAPMILSLQAFQKNLPE--------------------------STVDKLEKEKMPRKGGRWWFSWRRRDFP------------AEEHSSQREKAATRKQQGEKTEVL---SSDDDVPDSPVILEVPP----LPSSTPGYVPTYKKSLRLSSDQIRC-LNLNEGANDVVFSVTTQYQGTCRCKATIYLWNWDDKVVISDIDGTITKSDALGHILPQLGKDWTHQGITSLYHKIHLNGYKFLYCSARAIGMADLTKGYLQWVSEHGCGLPKGPILLSPSSLFSALHR----EVIEKKPEVFKVACLSDIQQLFLPQRQPFHAAFGNRPNDVFAYRQVGLPESRIFTVNPRGELIQELIKSHKSTYQRLGEVVELLFPPVVRGPSTDLASP-EYSNLSYWRKPLPYVDFEALA-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8J8YGA4-1", "uniprot_id": "A0A8J8YGA4_RAT", "id": "A0A8J8YGA4-1", "name": "phosphatidate phosphatase", "aln": "------------------------------------------------MNYVGQLAETVFGTVKELYRGLNPATLSGGIDVLVVKQVDGSFRCSPFHVRFGKLGVLRSREKVVDIEINGEPVDLHMKLGDSGEAFFVQELDSDEEDVPPRLCTSPIPWGG-LSGFPSDSQLGTA---------------SEPEGLVLT-----GRRKRRRRRKPRRRE-------DAADSSSEELEAGAESELTLLEKPMPESPSAWKE------------EEPSSQPKDIYPYSDGECTPQAN---------------------------------LSSADLMSPKSDSELELRPLEPSPLRAESHMQWAWGRLPKVAKAEHPEF--------------------------SLVLESMAEAICALPGEP------------------SPSS---MAGVDTLRSP-----------------------------------------------------ALQPGVREDMFHPDVEAYREETPMDS-------------PLAAPESKETK------TQNPRGTGHPPATKSWSWTTPESHTPSGRT-EVSRGRASLKRSQHLGPSDIYLDDLPSLDSENVALYFPKSDCGMGARRWSE------PSNQKLLE-------NPSREHTAECTLDSVDRIELSLCGGLADTRDISLEKFTQHMVSYEDLTKNPGLLDDPNLVVKINEKHYNWAVAAPMILSLQAFQKNLPE--------------------------STVDKLQKEKMPRKGGRWWFSWRRRDFP------------AEERSAQREKAATRKQQGEKTEVL---SSDDDVPDSPVILEVPP----LPSSTPGYVPTYKKSLRLSSNQIRC-LNLNEGANDVVFSVTTQYQGTCRCKATIYLWNWDDKVVISDIDGTITKSDALGHILPQLGKDWTHQGITSLYHKIHLNGYKFLYCSARAIGMAHLTKGYLQWVSEHGCGLPKGPILLSPSSLFSALHSTHLLLVIEKKPEVFKVACLSDIQQLFLPQRQPFYAAFGNRPNDVFAYRQVGLPESRIFTVNPRGELIQELIKNHKSTYQRLGEVVELLFPPVVRGPSTDLANP-EYSNLCYWRKPLPCVDFDTLV-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BQK8-1", "uniprot_id": "LPIN3_HUMAN", "id": "Q9BQK8-1", "name": "Phosphatidate phosphatase LPIN3", "aln": "------------------------------------------------MNYVGQLAETVFGTVKELYRGLNPATLSGGIDVLVVKQVDGSFRCSPFHVRFGKLGVLRSREKVVDIELNGEPVDLHMKLGDSGEAFFVQELESDDEHVPPGLCTSPIPWGG-LSGFPSDSQLGTA---------------SEPEGLVMAGTASTGRRKRRRRRKPKQKEDA-----VATDSSPEELEAGAESELSLPEKLRPEPPGVQLE------------EKSSLQPKDIYPYSDGEWPPQAS---------------------------------LSAGELTSPKSDSELEVRTPEPSPLRAESHMQWAWGRLPKVARAERPES--------------------------SVVLEGRAGATSPPRGGP------------------STPSTSVAGGVDPLGLP-----------------------------------------------------IQQTEAGAD-LQPDTEDP---TLVGP-------------PLHTPETEESK------TQSSGDMGLPPASKSWSWATLEVPVPTGQPERVSRGKGSPKRSQHLGPSDIYLDDLPSLDSENAALYFPQSDSGLGARRWSE------PSSQKSLR-------DPNPEHEPEPTLDTVDTIALSLCGGLADSRDISLEKFNQHSVSYQDLTKNPGLLDDPNLVVKINGKHYNWAVAAPMILSLQAFQKNLPK--------------------------STMDKLEREKMPRKGGRWWFSWRRRDFL------------AEERSAQKEKTAAKEQQGEKTEVL---SSDDDAPDSPVILEIPS----LPPSTPPSTPTYKKSLRLSSDQIRR-LNLQEGANDVVFSVTTQYQGTCRCKATIYLWKWDDKVVISDIDGTITKSDALGHILPQLGKDWTHQGITSLYHKIQLNGYKFLYCSARAIGMADLTKGYLQWVSEGGCSLPKGPILLSPSSLFSALHR----EVIEKKPEVFKVACLSDIQQLFLPHGQPFYAAFGNRPNDVFAYRQVGLPESRIFTVNPRGELIQELIKNHKSTYERLGEVVELLFPPVARGPSTDLANP-EYSNFCYWREPLPAVDLDTLD-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TSJ5-1", "uniprot_id": "A0AB32TSJ5_DANRE", "id": "A0AB32TSJ5-1", "name": "phosphatidate phosphatase", "aln": "-----------------------MAAEGRRGPAFTRHHPHHASIWSQTMNYVGQLAETVFVTVKELYRGLNPATLTGGIDVIVVRQPDGSFQCSPFHVRFGKLGVLRSKEKVVDIEINGEPVSLHMKLGDNGEAFFVEENEDFETRVPAHLCTSPIPTDVPEASEVTESQLSCS---------------NRRK----------KRRRKRVRSDTHLHEDD-----SSSSDEKESLDPDALKEESLLAASKSIYYSLSEEP-----------YEEASGAREVHPHSDGECSLNES---------------------------------VYFSRPSSPKSDSELCKAQESLGP-----QMQWNWGAFPKVCPSERVESDSLTHELPSPITPSDHSHFRTIHRQTSVDIDSTDSAVTVTVVRPEPQIGTVSPVSSDEAVCSSINTQLNVKFTNTLQSPDDCFSQSWSGLENKHSQEIIAEKEIETMTSCGNTVNESNNDASLDSVAHLENCSENNIVRTITFGESNQDLKAEAELNSILLPKHQSSVEILTLRASESEEGAGLETLPTNQNADSAGVTGSQEIIVQSEDPTVLEASKSADSQDKRKVKRSHHLGPSDIYLDDLSSLDPEVAALYFPKSEAESSDLRSSHGPDPSPPSGQMSPQSQGSANADSGTEYLSDSTSDSLD-VTMSLCG-RGDISQISKEKFMEHLVKFQDFVNNPGIIEDPNLVICINSKYYNWAVAAPMILSVQAFQKTLPK--------------------------STIEQLVKDKMPKKSGRWWFSWRRKDLNNI---PGNPKAGAEESQLEASASVAGPSTLKSSVEL---SSDEDG--SVSVRKNTE----LMNTAQCISQMYRKSLRLTSEQIES-LNLREGANKVVFSVTTQYQGTCRCEAAIYLWSYDDKIIISDIDGTITKSDALGHILPQLGKDWTHHGIAKLYHKIHQNGYKFLYCSARAIGMADITKGYLQWVNDRGTVLPKGPVLLAPSSLFSALHR----EVIEKKPEVFKIACLTDIRDLFSSVTQPFYAAFGNRTNDAYAYKEVGVPETHIFTVNPKGELIREKTKGNKSSYSHLSELVDHFFPLICKHPTTSFDCP-EFSHFTFWRAPLPPLDLQELI-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32567-1", "uniprot_id": "PAH1_YEAST", "id": "P32567-1", "name": "Phosphatidic acid phosphohydrolase 1", "aln": "------------------------------------------------MQYVGRALG----SVSKTWSSINPATLSGAIDVIVVEHPDGRLSCSPFHVRFGKFQILKPSQKKVQVFINEKLSNMPMKLSDSGEAYFVFEMGDQVTDVPDELLVSPVMSATSSPPQSPETSILEG----------------------------GTEGEGEGENENKKKEKK-------VLEEPDFLDINDTGDSGSKNSETTGSLSPTES--------STTTPPDSVEERKLVEQRTKNFQQKLN--------------------------------KKLTEIHIPSKLDNNGDLLLDTEGYKPNKNMMHDTDIQLKQLLKDEFGNDSDISS---------------------FIKEDKNGNIKIVNPYEH----------------------------LTDLSPP-----------------------------------------------------GTPPTMATSGSVLGLDAMESGSTLNSLSS----------SPSGSDTEDET------SFSKEQSSKSEKTSKKGTAGSGETEKRYIRTIRLTNDQLKCLNLTYGENDLKFSVDHGKAIVTSKLFVWRWDVPIVISDIDGTITKSDALGHVLAMIGKDWTHLGVAKLFSEISRNGYN--ILYLTARSAGQADSTRSYLRSIEQNGSKLPNGPVILSPDRTMAALRREVILKKPEVFKIACLNDIRSLYFE-----------------------------DSDNEVDTEEKSTPFFAGFGNRITDALSYRTVGIPSSRIFTINTEGEVHMELLELAGYRSS-YIHINELVDHFFPPVSLDSVDLRTNTSMVPGSPPNRTLDNFDSEITSGRKTLFRGNQEEKFTDVNFWRDPLVDIDNLSDISNDDSDNIDEDTDVSQQSNISRNRANSVKTAKVTKAPQRNVSGSTNNNEVLAASSDVENASDLVSSHSSSGSTPNKSTMSKGDIGKQIYLELGS--------PLASPKLRYLDDMDDEDSNYNRTKSRRASSAAATSIDKEFKKLSVSKAGAPTRIVSKINVSNDVHSLGNSDTESRREQSVNETGRNQLPHNSMDDKDLDSRVSDEFDDDEFDEDEFED-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:***: :.: : .:* ***:* **::*:.: :* **********: :*:. :* ::: :* . .: ***.:.***:** * . :* * .**: . . . . . .: : . : . .* *.: * : : . * ..: :. :. : . : . : * . : : . : . . .: ..* ::. . : : . . : .:: ::. : : . .: :: : : :: :. .: *. * * :. *: .. ::.. : . :*. *.: .. :*: : . . . :. *. : .* . :: . :.:* : :.: : . : : : . . :* .. . .*. . *. . : .: : : *: . : : : ", "identical_positions": 59, "similar_positions": 171, "identity": "5.11%" }, { "cls_id": "homologset.agr.SGD:S000004777", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97679-1", "uniprot_id": "MLH1_RAT", "id": "P97679-1", "name": "DNA mismatch repair protein Mlh1", "aln": "--MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMTENCLDAKSTNIQVIVREGGLKLIQIQDNGTGIRKEDLDIVCERFTTSKLQTFEDLAMISTYGFRGEALASISHVAHVTITTKTADGKCAYRASYSDGKLQAPPKPCAGNQGTLITVEDLFYNIITRKKALKNPSEEYGKILEVVGRYSIHNSGISFSVKKQGETVSDVRTLPNATTVDNIRSIFGNAVSRELIEVGCE--DKTLAFKMNGYISNANYSVKKCIF-LLFINHRLVESAALKKAIEAVYAAYLPKNTHPFLYLILEISPQNVDVNVHPTKHEVHFLHEESILERVQQHIESKLLGSNSSRMYFTQTLLPGLAG------PSGEAVKSTTGIASSSTSGSGDKVHAYQMVRTDSRDQKLDAFMQPVSRRLPSQPQD--PVPGNRTEGSPEKAMQKDQEISELPAPMEAAADSASLERESVIGASEVVAPQRHPSSPGSSRKRHPEDSDVEMMENDSRKEMTAACYPRRRIINLTSVLSLQEEINDRGHETLREMLRNHTFVGCVNPQW--ALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLPEPAPLFDFAMLALDSPESGWTEEDGPKEGLAEYIVEFLKKKAKMLADYFSVEIDEEGN--------LIGLPLLIDSYVPPLEGLPIFILRLATEVNWDEE-ECFESLSKECAVFYS--IRKQYILEESALSGQQSDMPGSPSKPWKWTVEHIIYKAFRSHLLPPKHFTEDGNVLQLANLPDLCKVFERC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JK91-1", "uniprot_id": "MLH1_MOUSE", "id": "Q9JK91-1", "name": "DNA mismatch repair protein Mlh1", "aln": "--MAFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTNIQVVVKEGGLKLIQIQDNGTGIRKEDLDIVCERFTTSKLQTFEDLASISTYGFRGEALASISHVAHVTITTKTADGKCAYRASYSDGKLQAPPKPCAGNQGTLITVEDLFYNIITRRKALKNPSEEYGKILEVVGRYSIHNSGISFSVKKQGETVSDVRTLPNATTVDNIRSIFGNAVSRELIEVGCE--DKTLAFKMNGYISNANYSVKKCIF-LLFINHRLVESAALRKAIETVYAAYLPKNTHPFLYLSLEISPQNVDVNVHPTKHEVHFLHEESILQRVQQHIESKLLGSNSSRMYFTQTLLPGLAG------PSGEAARPTTGVASSSTSGSGDKVYAYQMVRTDSREQKLDAFLQPVSSLGPSQPQDPAPVRGARTEGSPERATREDEEMLALPAPAEAAAESENLERESLMETSDAAQKAAPTSSPGSSRKRHREDSDVEMVENASGKEMTAACYPRRRIINLTSVLSLQEEISERCHETLREMLRNHSFVGCVNPQW--ALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWTEDDGPKEGLAEYIVEFLKKKAEMLADYFSVEIDEEGN--------LIGLPLLIDSYVPPLEGLPIFILRLATEVNWDEEKECFESLSKECAMFYS--IRKQYILEESTLSGQQSDMPGSTSKPWKWTVEHIIYKAFRSHLLPPKHFTEDGNVLQLANLPDLYKVFERC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40692-1", "uniprot_id": "MLH1_HUMAN", "id": "P40692-1", "name": "DNA mismatch repair protein Mlh1", "aln": "--MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDNGTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTADGKCAYRASYSDGKLKAPPKPCAGNQGTQITVEDLFYNIATRRKALKNPSEEYGKILEVVGRYSVHNAGISFSVKKQGETVADVRTLPNASTVDNIRSIFGNAVSRELIEIGCE--DKTLAFKMNGYISNANYSVKKCIF-LLFINHRLVESTSLRKAIETVYAAYLPKNTHPFLYLSLEISPQNVDVNVHPTKHEVHFLHEESILERVQQHIESKLLGSNSSRMYFTQTLLPGLAG------PSGEMVKSTTSLTSSSTSGSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQA--IVTEDKTDISSGRARQQDEEMLELPAPAEVAAKNQSLEGDTTKGTSEMSEKRGPTSS--NPRKRHREDSDVEMVEDDSRKEMTAACTPRRRIINLTSVLSLQEEINEQGHEVLREMLHNHSFVGCVNPQW--ALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWTEEDGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEEGN--------LIGLPLLIDNYVPPLEGLPIFILRLATEVNWDEEKECFESLSKECAMFYS--IRKQYISEESTLSGQQSEVPGSIPNSWKWTVEHIVYKALRSHILPPKHFTEDGNILQLANLPDLYKVFERC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13AAI6-1", "uniprot_id": "A0AB13AAI6_DANRE", "id": "A0AB13AAI6-1", "name": "DNA mismatch repair protein MLH1", "aln": "-----MAGVIRRLDETVVNRIAAGEIIQRPANAIKEMMENCLDAKSTNIQITVKEGGLKLILIQDNGTGIRKDDMEIVCERFTTSKLQSFEDLSSIATYGFRGEALASISHVAHVTITTKTADAKCAYRANYCDGKLKSPPKPCAGNQGTLISVEDLFYNVSTRRKALKSPSEEYSRIVEVVSRYAIHNSGKSFSVKKQGEMVADVKTLPNASVLDNIRVVFGVAVSRELIEVECE--DQKFAFKVKGYISNANYSVKKCIL-ILFINHRLVESSALKKAIETVYTAYLPKNTHPFLYLSLEIAPQNIDVNVHPTKHEVHFLHEDSIIESIQKHIESKLLGSNSSRTYFTQTLLPGLS------------ASASVAKASSSSADSQERVYAHQMVRTDSKAQKLDAFLQPSASSSSTAAQR-------KTEKTSSTSTAVQDLVELDDAELLTAADVEPCGGK------DPQTDAQPPGDEAPPRKRP----HVEEVKED----LTAASLPRRRIVKLTSIKELRDQIELQTHKGLQELLQNHSFVGSVSPQW--TLVQHQTKLYLLNTTKLSQELFYQILVYDFGNFGVLRLSNPAPLYDLAMLALDSEESGWTEEDGPKEGLAQYIVDFLKQKAEMLEEYFSLEIDAEGN--------LTGLPMLLDNYTPAMEGLPMFILRLATEVNWDKEKECFREFSVECSHFYS--IRKSYTLEADADEPQDAEMS------WQWKVEHVLFKALRSLFSPAKHLSEDGSVLQIASLPDLYKVFERC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7C1-1", "uniprot_id": "A1Z7C1_DROME", "id": "A1Z7C1-1", "name": "", "aln": "MAEYLQPGVIRKLDEVVVNRIAAGEIIQRPANALKELLENSLDAQSTHIQVQVKAGGLKLLQIQDNGTGIRREDLAIVCERFTTSKLTRFEDLSQIATFGFRGEALASISHVAHLSIQTKTAKEKCGYKATYADGKLQGQPKPCAGNQGTIICIEDLFYNMPQRRQALRSPAEEFQRLSEVLARYAVHNPRVGFTLRKQGDAQPALRTPVASSRSENIRIIYGAAISKELLEFSHR--DEVYKFEAECLITQVNYSAKKCQM-LLFINQRLVESTALRTSVDSIYATYLPRGHHPFVYMSLTLPPQNLDVNVHPTKHEVHFLYQEEIVDSIKQQVEARLLGSNATRTFYKQLRLPGAP-----------------DLDETQLADKTQRIYPKEMVRTDSTEQKLDKFLAPLVKSDSGVSSS-----------SSQEASRLPEESFRVTAAKKS------------------------------------------------------------REVRLSSVLDMRKRVERQCSVQLRSTLKNLVYVGCVDERR--ALFQHETRLYMCNTRSFSEELFYQRMIYEFQNCSEITISPPLPLKELLILSLESEAAGWTPEDGDKAELADGAADILLKKAPIMREYFGLRISEDGM--------LESLPSLLHQHRPCVAHLPVYLLRLATEVDWEQETRCFETFCRETARFY-----AQLDWREGATAGFS-----------RWTMEHVLFPAFKKYLLPPPRIKD--QIYELTNLPTLYKVFERC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38920-1", "uniprot_id": "MLH1_YEAST", "id": "P38920-1", "name": "DNA mismatch repair protein MLH1", "aln": "-----MSLRIKALDASVVNKIAAGEIIISPVNALKEMMENSIDANATMIDILVKEGGIKVLQITDNGSGINKADLPILCERFTTSKLQKFEDLSQIQTYGFRGEALASISHVARVTVTTKVKEDRCAWRVSYAEGKMLESPKPVAGKDGTTILVEDLFFNIPSRLRALRSHNDEYSKILDVVGRYAIHSKDIGFSCKKFGDSNYSLSVKPSYTVQDRIRTVFNKSVASNLITFHISKVEDLNLESVDGKVCNLNFISKKSISPIFFINNRLVTCDLLRRALNSVYSNYLPKGNRPFIYLGIVIDPAAVDVNVHPTKREVRFLSQDEIIEKIANQLHAELSAIDTSRTFKASSISTNKPESLIPFNDTIESDRNRKSLRQAQVVENSYTTANSQLRKAKRQENKLVRIDASQAKITSFLSSSQQFNFEGSSTKRQLSEPKVTNVSHSQEAEKLTLNESEQPRDANTINDNDLKDQPKKKQKLGDYKVPSIADDEKNALPIS--KDGYIRVPKERVNVNLTSIKKLREKVDDSIHRELTDIFANLNYVGVVDEERRLAAIQHDLKLFLIDYGSVCYELFYQIGLTDFANFGKINLQSTNVSDDIVLYNLLSEFDELN-DDASK----EKIISKIWDMSSMLNEYYSIELVNDGLDNDLKSVKLKSLPLLLKGYIPSLVKLPFFIYRLGKEVDWEDEQECLDGILREIALLYIPDMVPKVDTSDASLSEDEKAQFINRKEHISSLLEHVLFPCIKRRFLAPRHILK--DVVEIANLPDLYKVFERC", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *: ** ***:*****:* *.**:**: **.:**::* *:: *: **:*:: * ***:**.: *: *:********* ****: * *:**************:::: **. . :*.::..*.:**: *** **::** * :****:*: * :**:. :*: :: :*:.**::*. .*: :* *: : . : :.** ::. ::: :*: . :. . . : : *: **. ::***:*** . *: :::::*: ***:. :**:*: : : * :********:**:** ::.*:: : :::.:.* . :::* : . .. . .:. . :: ::. :** : . . .. : * :.*:*: .::..:. * . : * :** *. . : **: :*:: : ... ***** : :* * . : : . :: : * * . :*. * : . : . : :: :*:.:.: :* * .** *:. : * : **.:: **..**:*:.* .*: : * : :* . : . :**::: .:: : .. :: . .: :::.** * ******", "identical_positions": 183, "similar_positions": 232, "identity": "23.37%" }, { "cls_id": "homologset.agr.SGD:S000004779", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P30837-1", "uniprot_id": "AL1B1_HUMAN", "id": "P30837-1", "name": "Aldehyde dehydrogenase family 1 member B1, mitochondrial", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ML--RFLAPRLLSLQGR-TARYSSAAALPSPIL-------------------------NPDIPYNQ-LFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDRAVKAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYALDLDEVIKVYRYFAGWADKW-HGKTIPMDGQ----HFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHVDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFLERTVEKAKQR--KVG--NPFELDTQQGPQVDKEQFERVLGYIQLGQKEG--AKLLCGGER-FGERGFFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKK--IEEVVERANNTRYGLAAAVFTRDLDKAMYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIKVPQKNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66HF8-1", "uniprot_id": "AL1B1_RAT", "id": "Q66HF8-1", "name": "Aldehyde dehydrogenase family 1 member B1, mitochondrial", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLNARFLVPRLLCLQGR-TTSYSTAAALPNPIP-------------------------NPEIRYNQ-LFINNEWHDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDLAVRAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYVLDLDEVIKVYRYLAGWADKW-HGKTIPMDGE----HFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMDHAVDQCHEALFFNMGQCCCAGSRTFVEESIYHEFLERTVEKAKKR--KVG--NPFELDTQQGPQVDKEQFEKILGYIRLGQKEG--AKLLCGGER-FGERGFFIKPTVFGNVQDDMRIAREEIFGPVQPLFKFKK--IEEVIQRANNTRYGLAAAVFTRDLDKALYFSQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIKVSEKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05091-1", "uniprot_id": "ALDH2_HUMAN", "id": "P05091-1", "name": "Aldehyde dehydrogenase, mitochondrial", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRAA---ARFGPRLGRRLLSAAATQAVPAPNQ-------------------------QPEVFCNQ-IFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKY-HGKTIPIDGD----FFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSR--VVG--NPFDSKTEQGPQVDETQFKKILGYINTGKQEG--AKLLCGGGI-AADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKT--IEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11884-1", "uniprot_id": "ALDH2_RAT", "id": "P11884-1", "name": "Aldehyde dehydrogenase, mitochondrial", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRAALSTARRGPRLSR-LLSAAATSAVPAPNQ-------------------------QPEVFCNQ-IFINNEWHDAVSKKTFPTVNPSTGEVICQVAEGNKEDVDKAVKAAQAAFQLGSPWRRMDASDRGRLLYRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKY-HGKTIPIDGD----FFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEVGHLIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDVYDEFVERSVARAKSR--VVG--NPFDSRTEQGPQVDETQFKKILGYIKSGQQEG--AKLLCGGGA-AADRGYFIQPTVFGDVKDGMTIAKEEIFGPVMQILKFKT--IEEVVGRANNSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VLC5-1", "uniprot_id": "Q9VLC5_DROME", "id": "Q9VLC5-1", "name": "aldehyde dehydrogenase (NAD(+))", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRVLKTGALLRSQAKNFAAAVANYSSLPQPQT-------------------------TPDILYTG-VFINNEWHKSKSGKIFETINPTTAEVIAEIQCADKEDIDIAVQAARNAFKLGSPWRRMDASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWADKN-HGKTIPMDGD----FFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPAEQTSLTALYIAQLVKEAGFPEGVVNVVPGFG-TAGAALANHCDVDKVAFTGSTDVGKLIQLASGNTNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKKR--TVG--NPFDLNTEQGPQVNEEQMEKILGMIKTGKKQG--AKLVAGGSRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKK--LDEVIERANNSEYGLAAAVFTKDLDKANYIVGGLRAGTVWVNTYNVLAAQAPFGGYKMSGHGRENGEYALSNYTEVKSVIVKVAQKNS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47895-1", "uniprot_id": "AL1A3_HUMAN", "id": "P47895-1", "name": "Retinaldehyde dehydrogenase 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATAN------GAVENG--QPDRKPPALPRPIR-------------------------NLEVKFTK-IFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI-QGKTIPTDDN----VVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKR--PVG--DPFDVKTEQGPQIDQKQFDKILELIESGKKEG--AKLECGGSA-MEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKS--IEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGDKNP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K4D8-1", "uniprot_id": "AL1A3_RAT", "id": "Q8K4D8-1", "name": "Retinaldehyde dehydrogenase 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATAN------GAVENG--QPDGKPPALPRPIR-------------------------NLEVKFTK-IFINNDWHEPKSGRKFATYNPSTLEKICEVEEGDKPDVDKAVEAAQAAFQRGSPWRRLDALSRGQLLHQLADLIERDRAILATLETMDTGKPFLHAFFVDLEGCIKTFRYFAGWADKI-QGRTIPTDDN----VMCFTRHEPIGVCGAITPWNFPLLMLAWKLAPALCCGNTVVLKPAEQTPLTALYLASLIKEVGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGRNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYGEFVRRSVEFAKKR--PVG--DPFDAKTEQGPQIDQKQFDKILELIESGKKEG--AKLECGGSA-MEDRGLFIKPTVFSDVTDNMRIAKEEIFGPVQPILKFKN--LEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWVNCYNAFYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLDEKNP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00352-1", "uniprot_id": "AL1A1_HUMAN", "id": "P00352-1", "name": "Aldehyde dehydrogenase 1A1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSS-------------------SGTPDLPVLLT-------------------------DLKIQYTK-IFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWADKI-QGRTIPIDGN----FFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKY--ILG--NPLTPGVTQGPQIDKEQYDKILDLIESGKKEG--AKLECGGGP-WGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKS--LDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKISQKNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P51647-1", "uniprot_id": "AL1A1_RAT", "id": "P51647-1", "name": "Aldehyde dehydrogenase 1A1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSS-------------------PAQPAVPAPLA-------------------------NLKIQHTK-IFINNEWHDSVSGKKFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLMERDRLLLATIEAINGGKVFANAYLSDLGGSIKALKYCAGWADKI-HGQTIPSDGD----IFTFTRREPIGVCGQIIPWNFPLLMFIWKIGPALSCGNTVVVKPAEQTPLTALHMASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTQVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDIAVEFAHHGVFYHQGQCCVAASRIFVEESVYDEFVRKSVERAKKY--VLG--NPLTQGINQGPQIDKEQHDKILDLIESGKKEG--AKLECGGGR-WGNKGFFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKS--IDDVIKRANNTTYGLAAGVFTKDLDRAITVSSALQAGVVWVNCYMILSAQCPFGGFKMSGNGRELGEHGLYEYTELKTVAMKISQKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O94788-1", "uniprot_id": "AL1A2_HUMAN", "id": "O94788-1", "name": "Retinal dehydrogenase 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSSKIEMPGEVKADPA--ALMASLHLLPSPTP-------------------------NLEIKYTK-IFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKI-HGMTIPVDGD----YFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRR--VVG--SPFDPTTEQGPQIDKKQYNKILELIQSGVAEG--AKLECGGKG-LGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKT--MDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63639-1", "uniprot_id": "AL1A2_RAT", "id": "Q63639-1", "name": "Retinal dehydrogenase 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSSEIAMPGEVKADPA--ALMASLQLLPSPTP-------------------------NLEIKYTK-IFINNEWQNSESGRVFPVCNPATGEQVCEVQEADKVDIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRATLATMESLNGGKPFLQAFYIDLQGVIKTLRYYAGWADKI-HGMTIPVDGD----YFTFTRHEPIGVCGQIIPWNFPLLMFTWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVVNILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVKRSVERAKRR--IVG--SPFDPTTEQGPQIDKKQYNKILELIQSGVAEG--AKLECGGKG-LGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKT--MDEVIERANNSDFGLVAAVFTNDINKALMVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0B4K6I6-1", "uniprot_id": "A0A0B4K6I6_DROME", "id": "A0A0B4K6I6-1", "name": "Aldehyde dehydrogenase domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMN------KLQKLLAHQLAVSRKWSKFDHTYA-------------------------QCEPNYCQ-LFINNEFVDSVSGKTFATFNPATSKEIVQVSEGDKADIDLAVKAAKKAFHRDSEWRKLSPLQRTNLMNKLCALMDRDKAFLASLETQDNGKPYAEA-LFDVTYSILTLQYYAGWTDKF-FGDTIPAGG-----FVSMTRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTALHMAALAKEAGFPAGVINVVNGFGPTAGAAISAHPDIAKVAFTGSVEIGRIVMQAAATSNLKRVSLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFVAKAAAKAKAR--KVG--NPFEQNVQQGPQIDDDMLTKVLGYIESGKKEG--AKLQAGGKR-IGNVGFFVEPTVFSDVKDDMRIAQEEIFGPVQSIFKFSS--LEEMIDRANNVQYGLAAGVITNDINKALKFANNVDAGSVWINCYDAVLPSTPFGGYKHSGIGRELGKDGLDNYLETKTITMKLL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54114-1", "uniprot_id": "ALDH3_YEAST", "id": "P54114-1", "name": "Aldehyde dehydrogenase [NAD(P)+] 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPTLYTDIEIPQL-------------------------KISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAFD--NVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPFHSNAKQDLAQIIELTRYYAGAVDKFNMGETIPLTFN----KFAYTLKVPFGVVAQIVPWNYPLAMACRKMQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVVNVIPGYGSVVGKALGTHMDIDKISFTGSTKVGGSVLEASGQSNLKDITLECGGKSPALVFEDADLDKAIEWVANGIFFNSGQICTANSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKKEEKLDMFQTSEFPIGGAKGYFIPPTIFTDVPETSKLLRDEIFGPVVVVSKFTN--YDDALKLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINQTNQEEAKVPFGGFKMSGIGRESGDTGVDNYLQIKSVHVDLSLDK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q3SY69-1", "uniprot_id": "AL1L2_HUMAN", "id": "Q3SY69-1", "name": "Mitochondrial 10-formyltetrahydrofolate dehydrogenase", "aln": "MLRRGSQALRRFSTGRVYFKNKLKLALIGQSLFGQEVYSHLR-KEGHRVVGVFTVPDKDGKADPLALAAEKDGTPVFKLPKWRVKGKTIKEVAEAYRSVGAELNVLPFCTQFIPMDIIDSPKHGSIIYHPSILPRHRGASAINWTLIMGDKKAGFSVFWADDGLDTGPILLQRSCDVEPNDTVDALYNRFLFPEGIKAMVEAVQLIADGKAPRIPQPEEGATYEG-IQKKENAEISWDQSAEVLHNWIRGHDKVPGAWTEING-----QMVTFYGSTLLNS-SVPPGEPLEIKGAKKPGLVTKNGLVLFGNDGKALTVRNLQFEDGKMIPASQYFSTGE-TSVVELTAEEVKVAETIKVIWAGILSNVPIIEDSTDFFKSGASSMDVARLVEEIRQKCGGLQLQNEDVYMATKFEGFIQKVVRKLRGEDQ---EVELVVDYISKEVNEIMVKMPYQCFINGQFTDADDGKTYDTINPTDGSTICKVSYASLADVDKAVAAAKDAFEN-GEWGRMNARERGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKI-QGSTIPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVKAGFPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKSPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEESIHDEFVTRVVEEIKKM--KIG--DPLDRSTDHGPQNHKAHLEKLLQYCETGVKEG--ATLVYGGRQVQ-RPGFFMEPTVFTDVEDYMYLAKEESFGPIMVISKFQNGDIDGVLQRANSTEYGLASGVFTRDINKAMYVSEKLEAGTVFINTYNKTDVAAPFGGVKQSGFGKDLGEEALNEYLKTKTVTLEY-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K009-1", "uniprot_id": "AL1L2_MOUSE", "id": "Q8K009-1", "name": "Mitochondrial 10-formyltetrahydrofolate dehydrogenase", "aln": "MLWRGSQALRHFSTSRVYFKNKLKLALIGQSLFGQEVYSQLL-KEGHRVVGVFTVPDKDGKADPLALAAEKDGTPVFKFPRWRLKGKTIKEVAEAYQSVGAELNVLPFCTQFIPMDVIDSPKHGSIIYHPSLLPRHRGASAINWTLIMGDKKAGFSVFWADDGLDTGPILLQRSCDVKPNDTVDSLYNRFLFPEGIKAMVEAVQLIADGKAPRTPQPEEGATYEG-IQKKENAEVSWDQPAEGLHNWIRGHDKVPGAWAEING-----QMVTFYGSSLLTS-SVPSGEPLDIRGAKKPGLVTKNGLVLFGNDGKALMVRNLQFEDGKMIPASQYFSAGE-TSVVELTAEELKVAETIKVIWARILSNTPVIEDSTDFFKSGASSMDVVRLVEEIRQSCGGLQLQNEDVYMATKFGDFIQKVVRRLRGEDE---EAEMVVDYVSKEVNGMTVKIPYQCFINGQFVDAEDGETYATVNPTDGTTICRVSYASLADVDRAVAAAKDAFEN-GEWGRMNARDRGRLMYRLADLMEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKI-QGSTIPINQARPNYNLTFTKKEPLGACAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELTVKAGFPKGVINIIPGSGGVAGQRLSQHPDIRKLGFTGSTSVGKQIMKSCAVSNLKKVSLELGGKSPLIIFSDCDLEKAVRMGMGAVFFNKGENCIAAGRLFVEEAIHDEFVTRVVEEIKKM--KIG--DPLDRSTDHGPQNHRAHLEKLLQYCETGVQEG--ATLVYGGRQVQ-RPGFFMEPTVFTGVEDHMYLAKEESFGPIMVISKFQNGDIDGVLQRANNTEYGLASGVFTRDINKAMYVSDKLEAGTVFINTYNKTDVAAPFGGMKQSGFGKDLGEEALNEYLKIKTVTLEY-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1RK21-1", "uniprot_id": "A0A8M1RK21_DANRE", "id": "A0A8M1RK21-1", "name": "10-formyltetrahydrofolate dehydrogenase", "aln": "MLWTANTIMRKFSSSSVYYQNKLKLALIGQSLFGQEVYTNLR-KQGHKVVGVFTVPDKDGKADPLAVVAEKDGTPVFKFPRWRVKGKPIPEVVEAYKAVGAELNVMPFCSQFIPMNVIDFPKHGSIIYHPSILPKHRGASAINWTLIEGDKKAGFSVFWADDGLDTGPILLQKECQVEPNDTVDTLYNRFLFPEGIKAMVEAVQLIANGKAPKIPQSEEGASYEG-IQKKSNAKVNMAQPAEAIHNWIRGHDKVPGAWVVMDG-----KPVTVYGSSVLSG-SVPAGQPIDIEGASQPGLITKSGLLLFGSDGKALQVKSLQFEDGKMIPASKYFSSEE-SASLDLTDDEKKMAEEIRAIWKGILSNVAAIEETTDFFKCGAASMDVVRLVEEVKQKCAGVQLQNEDVYMATTFQSFIQMLVRRLRGEDQ---EEEMLIDYATKEVNNMTVKMPYQCFINGKFEDADDGKTYNTVNPTDGSVICKVSYASVADVDKAVSAAKEAFDN-GPWGKMNPRDRGQLLYRLADLMEEHQEELATIETIDSGAVYTLALKTHVGMSIQTFRYFAGWCDKI-QGSTIPINQARPNRNLTFTKKEPLGVCAIVIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELTIKAGIPKGVINIVPGSGGLVGQRMSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKSPLIIFSDCDMDKAVRMGMSSVYFNKGENCIAAGRLFVEESIHDEYIRRVVEEIKKM--KIG--DPLDRSTDHGPQNHKAHMDKLVEYCEIGVKEG--ATLVYGGRQVD-RPGFFMEPTVFTDVEDHMFIAKEESFGPVMVVSKFKDGDVDGVLSRANDTEFGLASGVFTRDINKAMYVSERLEAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGEDALHEYLRTKAVTVEY-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O75891-1", "uniprot_id": "AL1L1_HUMAN", "id": "O75891-1", "name": "Cytosolic 10-formyltetrahydrofolate dehydrogenase", "aln": "----------------------MKIAVIGQSLFGQEVYCHLR-KEGHEVVGVFTVPDKDGKADPLGLEAEKDGVPVFKYSRWRAKGQALPDVVAKYQALGAELNVLPFCSQFIPMEIISAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFSIFWADDGLDTGDLLLQKECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGKAPRLPQPEEGATYEG-IQKKETAKINWDQPAEAIHNWIRGNDKVPGAWTEACE-----QKLTFFNSTLNTSGLVPEGDALPIPGAHRPGVVTKAGLILFGNDDKMLLVKNIQLEDGKMILASNFFKGAA-SSVLELTEAELVTAEAVRSVWQRILPKVLEVEDSTDFFKSGAASVDVVRLVEEVKELCDGLELENEDVYMASTFGDFIQLLVRKLRGDDE---EGECSIDYVEMAVNKRTVRMPHQLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFEN-GRWGKISARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKI-QGSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDEFVRRVVEEVRKM--KVG--NPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEG--ATLVCGGNQVP-RPGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRVKTVTFEY-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R0Y6-1", "uniprot_id": "AL1L1_MOUSE", "id": "Q8R0Y6-1", "name": "Cytosolic 10-formyltetrahydrofolate dehydrogenase", "aln": "----------------------MKIAVIGQSLFGQEVYCQLR-KEGHEVVGVFTIPDKDGKADPLGLEAEKDGVPVFKFPRWRARGQALPEVVAKYQALGAELNVLPFCSQFIPMEVINAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFTIFWADDGLDTGDLLLQKECDVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGTAPRRPQPEEGATYEG-IQKKETAMINWDQPAEAIHNWIRGNDKVPGAWTEACG-----QKLTFFNSTLNTSGLVAQGEALPIPGAHRPGLVTKAGLILFGNDDRMLLVKNIQLEDGKMMPASQFFKGSA-SSALELTEEELATAEAVRSSWMRILPNVPEVEDSTDFFKSGAASVDVVRLVEEVKELCDGLELENEDVYMATTFGDFIQLLVRKLRGEDG---ESECVINYVEKAVKKLTLQMPYQLFIGGEFVDAEGAKTYSTINPTDGSVICQVSLAQVSDVDKAVAAAKEAFEN-GLWGKINARDRGRLLYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKI-QGATIPINQARPNRNLTLTKKEPVGVCGIVIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNILPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCALSNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDQFVQKVVEEVGKM--KIG--NPLDRDTNHGPQNHEAHLRKLVEYCQRGVKEG--ATLVCGGNQVP-RPGFFFQPTVFTDVEDHMYIAKEESFGPIMIISRFADGDVDAVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRIKTVTFEY-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VIC9-1", "uniprot_id": "Q9VIC9_DROME", "id": "Q9VIC9-1", "name": "10-formyltetrahydrofolate dehydrogenase", "aln": "------------------MALKMRIAIIGQSNFAADVLELLLDRSNIQIVGVFTIPDKGSREDILATTATIHNIPVFKFACWRRKGVALPEVLEQYKSVGATLNVLPFCSQFIPMEVINGALLGSICYHPSILPRHRGASAISWTLIEGDEVAGFSIFWADDGLDTGPLLLTRQTNVESTDTLDTIYKRFLYPEGVKAMGVAVDMVASGTAPKIIQPEVGATYDPAMFKTENQVINLQATAEKIWNFVRGLDSVPGAIATVLHGNGTEEQIRLFGAHLYSAGPVSNGKVLRLRGLTKTAWIHSGGLLIEGTDGAFVNIRRIKR-GTKVISASEWFKQAEDQSITDFSEDELVKRSLLAGIWKAILK--EDVESSTDFFASGAGSMDVVRLVEEVKEAFD-VPLQNEQVFMAPVFEEFFSLLVRFLRQGSAGFGNQQLDFEAFTLKANKREIRVPTQLFINGEFVDAEAQRTLEIVNPTNEEVLCKVACASATDVDKAVRAAHSAFY--GSWRQITPRQRGQLMLNLADLMERNKEELATIESVDSGAVYTLALKTHVGMSIEAWRYFAGWCDKI-QGNTIPVNPARPNNVLTFTRKEPIGVCGLITPWNYPLMMLSWKMAACIAAGNTCLIKPAQTCPLTALKFAELTVRAGFPPGVINVLPGKGSDAGQAVADHELVRKLGFTGSTPIGKHIMKSCADSNLKKCSLELGGKSPLIIFADCDMDKAVKHGMSSVFFNKGENCIAAGRLFVEDRIHDEFIRRVLKDLRTM--TIG--DPLDRSTAHGPQNHKAHFDKLLEFCRRGVDEG--AKLVYGGCRVPNLKGYFFTPTVFTNVTDDMFIAQEESFGPIMIISKFNGSDIDSLMQRANRTEYGLASGVFTKDIGKALNFADRIEAGTVFVNVYNKTDVAAPFGGFKQSGYGKDLGQEALNEYLKTKCVTVEY-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **...: . . **: : . .. *:* ** **: ** . * . * : .* *::..: **::*: : * : .: : :* ** ** * *** . * : *.*. . : ***:*: * * .:. * . ::* *: .*: * .. * ..*:* **:*:: * * .* :. * : *:.****. :* : :.. :*:* :** **:.* :: * ::: *: .:: : *: * * .* :*.. :: ::: : * .*: ** :: . * : : . * *. **:* * : : ::* ***: : :* : : ** :** :.*:*.:: :* . : :* *::* **** * ** *:: *. .. * . * : .. ", "identical_positions": 110, "similar_positions": 136, "identity": "11.59%" }, { "cls_id": "homologset.agr.SGD:S000004780", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P30837-1", "uniprot_id": "AL1B1_HUMAN", "id": "P30837-1", "name": "Aldehyde dehydrogenase family 1 member B1, mitochondrial", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ML--RFLAPRLLSLQGR-TARYSSAAALPSPIL-------------------------NPDIPYNQ-LFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDRAVKAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYALDLDEVIKVYRYFAGWADKWH-GKTIPMDGQ----HFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHVDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFLERTVEKAKQR--KVG--NPFELDTQQGPQVDKEQFERVLGYIQLGQKEG--AKLLCGGER-FGERGFFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKK--IEEVVERANNTRYGLAAAVFTRDLDKAMYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIKVPQKNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66HF8-1", "uniprot_id": "AL1B1_RAT", "id": "Q66HF8-1", "name": "Aldehyde dehydrogenase family 1 member B1, mitochondrial", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLNARFLVPRLLCLQGR-TTSYSTAAALPNPIP-------------------------NPEIRYNQ-LFINNEWHDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDLAVRAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYVLDLDEVIKVYRYLAGWADKWH-GKTIPMDGE----HFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMDHAVDQCHEALFFNMGQCCCAGSRTFVEESIYHEFLERTVEKAKKR--KVG--NPFELDTQQGPQVDKEQFEKILGYIRLGQKEG--AKLLCGGER-FGERGFFIKPTVFGNVQDDMRIAREEIFGPVQPLFKFKK--IEEVIQRANNTRYGLAAAVFTRDLDKALYFSQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIKVSEKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05091-1", "uniprot_id": "ALDH2_HUMAN", "id": "P05091-1", "name": "Aldehyde dehydrogenase, mitochondrial", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRAA---ARFGPRLGRRLLSAAATQAVPAPNQ-------------------------QPEVFCNQ-IFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYH-GKTIPIDGD----FFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSR--VVG--NPFDSKTEQGPQVDETQFKKILGYINTGKQEG--AKLLCGGGI-AADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKT--IEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11884-1", "uniprot_id": "ALDH2_RAT", "id": "P11884-1", "name": "Aldehyde dehydrogenase, mitochondrial", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRAALSTARRGPRLSR-LLSAAATSAVPAPNQ-------------------------QPEVFCNQ-IFINNEWHDAVSKKTFPTVNPSTGEVICQVAEGNKEDVDKAVKAAQAAFQLGSPWRRMDASDRGRLLYRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYH-GKTIPIDGD----FFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEVGHLIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDVYDEFVERSVARAKSR--VVG--NPFDSRTEQGPQVDETQFKKILGYIKSGQQEG--AKLLCGGGA-AADRGYFIQPTVFGDVKDGMTIAKEEIFGPVMQILKFKT--IEEVVGRANNSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VLC5-1", "uniprot_id": "Q9VLC5_DROME", "id": "Q9VLC5-1", "name": "aldehyde dehydrogenase (NAD(+))", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRVLKTGALLRSQAKNFAAAVANYSSLPQPQT-------------------------TPDILYTG-VFINNEWHKSKSGKIFETINPTTAEVIAEIQCADKEDIDIAVQAARNAFKLGSPWRRMDASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWADKNH-GKTIPMDGD----FFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPAEQTSLTALYIAQLVKEAGFPEGVVNVVPGFG-TAGAALANHCDVDKVAFTGSTDVGKLIQLASGNTNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKKR--TVG--NPFDLNTEQGPQVNEEQMEKILGMIKTGKKQG--AKLVAGGSRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKK--LDEVIERANNSEYGLAAAVFTKDLDKANYIVGGLRAGTVWVNTYNVLAAQAPFGGYKMSGHGRENGEYALSNYTEVKSVIVKVAQKNS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47895-1", "uniprot_id": "AL1A3_HUMAN", "id": "P47895-1", "name": "Retinaldehyde dehydrogenase 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATAN------GAVENG--QPDRKPPALPRPIR-------------------------NLEVKFTK-IFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ-GKTIPTDDN----VVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKR--PVG--DPFDVKTEQGPQIDQKQFDKILELIESGKKEG--AKLECGGSA-MEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKS--IEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGDKNP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K4D8-1", "uniprot_id": "AL1A3_RAT", "id": "Q8K4D8-1", "name": "Retinaldehyde dehydrogenase 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATAN------GAVENG--QPDGKPPALPRPIR-------------------------NLEVKFTK-IFINNDWHEPKSGRKFATYNPSTLEKICEVEEGDKPDVDKAVEAAQAAFQRGSPWRRLDALSRGQLLHQLADLIERDRAILATLETMDTGKPFLHAFFVDLEGCIKTFRYFAGWADKIQ-GRTIPTDDN----VMCFTRHEPIGVCGAITPWNFPLLMLAWKLAPALCCGNTVVLKPAEQTPLTALYLASLIKEVGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGRNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYGEFVRRSVEFAKKR--PVG--DPFDAKTEQGPQIDQKQFDKILELIESGKKEG--AKLECGGSA-MEDRGLFIKPTVFSDVTDNMRIAKEEIFGPVQPILKFKN--LEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWVNCYNAFYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLDEKNP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00352-1", "uniprot_id": "AL1A1_HUMAN", "id": "P00352-1", "name": "Aldehyde dehydrogenase 1A1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSS-------------------SGTPDLPVLLT-------------------------DLKIQYTK-IFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWADKIQ-GRTIPIDGN----FFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKY--ILG--NPLTPGVTQGPQIDKEQYDKILDLIESGKKEG--AKLECGGGP-WGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKS--LDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKISQKNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P51647-1", "uniprot_id": "AL1A1_RAT", "id": "P51647-1", "name": "Aldehyde dehydrogenase 1A1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSS-------------------PAQPAVPAPLA-------------------------NLKIQHTK-IFINNEWHDSVSGKKFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLMERDRLLLATIEAINGGKVFANAYLSDLGGSIKALKYCAGWADKIH-GQTIPSDGD----IFTFTRREPIGVCGQIIPWNFPLLMFIWKIGPALSCGNTVVVKPAEQTPLTALHMASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTQVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDIAVEFAHHGVFYHQGQCCVAASRIFVEESVYDEFVRKSVERAKKY--VLG--NPLTQGINQGPQIDKEQHDKILDLIESGKKEG--AKLECGGGR-WGNKGFFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKS--IDDVIKRANNTTYGLAAGVFTKDLDRAITVSSALQAGVVWVNCYMILSAQCPFGGFKMSGNGRELGEHGLYEYTELKTVAMKISQKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O94788-1", "uniprot_id": "AL1A2_HUMAN", "id": "O94788-1", "name": "Retinal dehydrogenase 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSSKIEMPGEVKADPA--ALMASLHLLPSPTP-------------------------NLEIKYTK-IFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH-GMTIPVDGD----YFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRR--VVG--SPFDPTTEQGPQIDKKQYNKILELIQSGVAEG--AKLECGGKG-LGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKT--MDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63639-1", "uniprot_id": "AL1A2_RAT", "id": "Q63639-1", "name": "Retinal dehydrogenase 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSSEIAMPGEVKADPA--ALMASLQLLPSPTP-------------------------NLEIKYTK-IFINNEWQNSESGRVFPVCNPATGEQVCEVQEADKVDIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRATLATMESLNGGKPFLQAFYIDLQGVIKTLRYYAGWADKIH-GMTIPVDGD----YFTFTRHEPIGVCGQIIPWNFPLLMFTWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVVNILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVKRSVERAKRR--IVG--SPFDPTTEQGPQIDKKQYNKILELIQSGVAEG--AKLECGGKG-LGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKT--MDEVIERANNSDFGLVAAVFTNDINKALMVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0B4K6I6-1", "uniprot_id": "A0A0B4K6I6_DROME", "id": "A0A0B4K6I6-1", "name": "Aldehyde dehydrogenase domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMN------KLQKLLAHQLAVSRKWSKFDHTYA-------------------------QCEPNYCQ-LFINNEFVDSVSGKTFATFNPATSKEIVQVSEGDKADIDLAVKAAKKAFHRDSEWRKLSPLQRTNLMNKLCALMDRDKAFLASLETQDNGKPYAEA-LFDVTYSILTLQYYAGWTDKFF-GDTIPAGG-----FVSMTRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTALHMAALAKEAGFPAGVINVVNGFGPTAGAAISAHPDIAKVAFTGSVEIGRIVMQAAATSNLKRVSLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFVAKAAAKAKAR--KVG--NPFEQNVQQGPQIDDDMLTKVLGYIESGKKEG--AKLQAGGKR-IGNVGFFVEPTVFSDVKDDMRIAQEEIFGPVQSIFKFSS--LEEMIDRANNVQYGLAAGVITNDINKALKFANNVDAGSVWINCYDAVLPSTPFGGYKHSGIGRELGKDGLDNYLETKTITMKLL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47771-1", "uniprot_id": "ALDH2_YEAST", "id": "P47771-1", "name": "Aldehyde dehydrogenase [NAD(P)+] 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPTLYTDIEIPQL-------------------------KISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAFD--NVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPYHSNAKGDLAQILQLTRYFAGSADKFDKGATIPLTFN----KFAYTLKVPFGVVAQIVPWNYPLAMACWKLQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVVNIVPGYGSLVGQALASHMDIDKISFTGSTKVGGFVLEASGQSNLKDVTLECGGKSPALVFEDADLDKAIDWIAAGIFYNSGQNCTANSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKREEKLDMFQTSEFPIGGAKGYFIPPTIFTDVPQTSKLLQDEIFGPVVVVSKFTN--YDDALKLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINSSNDEDVTVPFGGFKMSGIGRELGQSGVDTYLQTKAVHINLSLDN-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q3SY69-1", "uniprot_id": "AL1L2_HUMAN", "id": "Q3SY69-1", "name": "Mitochondrial 10-formyltetrahydrofolate dehydrogenase", "aln": "MLRRGSQALRRFSTGRVYFKNKLKLALIGQSLFGQEVYSHLR-KEGHRVVGVFTVPDKDGKADPLALAAEKDGTPVFKLPKWRVKGKTIKEVAEAYRSVGAELNVLPFCTQFIPMDIIDSPKHGSIIYHPSILPRHRGASAINWTLIMGDKKAGFSVFWADDGLDTGPILLQRSCDVEPNDTVDALYNRFLFPEGIKAMVEAVQLIADGKAPRIPQPEEGATYEG-IQKKENAEISWDQSAEVLHNWIRGHDKVPGAWTEING-----QMVTFYGSTLLNS-SVPPGEPLEIKGAKKPGLVTKNGLVLFGNDGKALTVRNLQFEDGKMIPASQYFSTGE-TSVVELTAEEVKVAETIKVIWAGILSNVPIIEDSTDFFKSGASSMDVARLVEEIRQKCGGLQLQNEDVYMATKFEGFIQKVVRKLRGEDQ---EVELVVDYISKEVNEIMVKMPYQCFINGQFTDADDGKTYDTINPTDGSTICKVSYASLADVDKAVAAAKDAFEN-GEWGRMNARERGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQ-GSTIPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVKAGFPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKSPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEESIHDEFVTRVVEEIKKM--KIG--DPLDRSTDHGPQNHKAHLEKLLQYCETGVKEG--ATLVYGGRQVQ-RPGFFMEPTVFTDVEDYMYLAKEESFGPIMVISKFQNGDIDGVLQRANSTEYGLASGVFTRDINKAMYVSEKLEAGTVFINTYNKTDVAAPFGGVKQSGFGKDLGEEALNEYLKTKTVTLEY-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K009-1", "uniprot_id": "AL1L2_MOUSE", "id": "Q8K009-1", "name": "Mitochondrial 10-formyltetrahydrofolate dehydrogenase", "aln": "MLWRGSQALRHFSTSRVYFKNKLKLALIGQSLFGQEVYSQLL-KEGHRVVGVFTVPDKDGKADPLALAAEKDGTPVFKFPRWRLKGKTIKEVAEAYQSVGAELNVLPFCTQFIPMDVIDSPKHGSIIYHPSLLPRHRGASAINWTLIMGDKKAGFSVFWADDGLDTGPILLQRSCDVKPNDTVDSLYNRFLFPEGIKAMVEAVQLIADGKAPRTPQPEEGATYEG-IQKKENAEVSWDQPAEGLHNWIRGHDKVPGAWAEING-----QMVTFYGSSLLTS-SVPSGEPLDIRGAKKPGLVTKNGLVLFGNDGKALMVRNLQFEDGKMIPASQYFSAGE-TSVVELTAEELKVAETIKVIWARILSNTPVIEDSTDFFKSGASSMDVVRLVEEIRQSCGGLQLQNEDVYMATKFGDFIQKVVRRLRGEDE---EAEMVVDYVSKEVNGMTVKIPYQCFINGQFVDAEDGETYATVNPTDGTTICRVSYASLADVDRAVAAAKDAFEN-GEWGRMNARDRGRLMYRLADLMEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQ-GSTIPINQARPNYNLTFTKKEPLGACAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELTVKAGFPKGVINIIPGSGGVAGQRLSQHPDIRKLGFTGSTSVGKQIMKSCAVSNLKKVSLELGGKSPLIIFSDCDLEKAVRMGMGAVFFNKGENCIAAGRLFVEEAIHDEFVTRVVEEIKKM--KIG--DPLDRSTDHGPQNHRAHLEKLLQYCETGVQEG--ATLVYGGRQVQ-RPGFFMEPTVFTGVEDHMYLAKEESFGPIMVISKFQNGDIDGVLQRANNTEYGLASGVFTRDINKAMYVSDKLEAGTVFINTYNKTDVAAPFGGMKQSGFGKDLGEEALNEYLKIKTVTLEY-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1RK21-1", "uniprot_id": "A0A8M1RK21_DANRE", "id": "A0A8M1RK21-1", "name": "10-formyltetrahydrofolate dehydrogenase", "aln": "MLWTANTIMRKFSSSSVYYQNKLKLALIGQSLFGQEVYTNLR-KQGHKVVGVFTVPDKDGKADPLAVVAEKDGTPVFKFPRWRVKGKPIPEVVEAYKAVGAELNVMPFCSQFIPMNVIDFPKHGSIIYHPSILPKHRGASAINWTLIEGDKKAGFSVFWADDGLDTGPILLQKECQVEPNDTVDTLYNRFLFPEGIKAMVEAVQLIANGKAPKIPQSEEGASYEG-IQKKSNAKVNMAQPAEAIHNWIRGHDKVPGAWVVMDG-----KPVTVYGSSVLSG-SVPAGQPIDIEGASQPGLITKSGLLLFGSDGKALQVKSLQFEDGKMIPASKYFSSEE-SASLDLTDDEKKMAEEIRAIWKGILSNVAAIEETTDFFKCGAASMDVVRLVEEVKQKCAGVQLQNEDVYMATTFQSFIQMLVRRLRGEDQ---EEEMLIDYATKEVNNMTVKMPYQCFINGKFEDADDGKTYNTVNPTDGSVICKVSYASVADVDKAVSAAKEAFDN-GPWGKMNPRDRGQLLYRLADLMEEHQEELATIETIDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIQ-GSTIPINQARPNRNLTFTKKEPLGVCAIVIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELTIKAGIPKGVINIVPGSGGLVGQRMSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKSPLIIFSDCDMDKAVRMGMSSVYFNKGENCIAAGRLFVEESIHDEYIRRVVEEIKKM--KIG--DPLDRSTDHGPQNHKAHMDKLVEYCEIGVKEG--ATLVYGGRQVD-RPGFFMEPTVFTDVEDHMFIAKEESFGPVMVVSKFKDGDVDGVLSRANDTEFGLASGVFTRDINKAMYVSERLEAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGEDALHEYLRTKAVTVEY-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O75891-1", "uniprot_id": "AL1L1_HUMAN", "id": "O75891-1", "name": "Cytosolic 10-formyltetrahydrofolate dehydrogenase", "aln": "----------------------MKIAVIGQSLFGQEVYCHLR-KEGHEVVGVFTVPDKDGKADPLGLEAEKDGVPVFKYSRWRAKGQALPDVVAKYQALGAELNVLPFCSQFIPMEIISAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFSIFWADDGLDTGDLLLQKECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGKAPRLPQPEEGATYEG-IQKKETAKINWDQPAEAIHNWIRGNDKVPGAWTEACE-----QKLTFFNSTLNTSGLVPEGDALPIPGAHRPGVVTKAGLILFGNDDKMLLVKNIQLEDGKMILASNFFKGAA-SSVLELTEAELVTAEAVRSVWQRILPKVLEVEDSTDFFKSGAASVDVVRLVEEVKELCDGLELENEDVYMASTFGDFIQLLVRKLRGDDE---EGECSIDYVEMAVNKRTVRMPHQLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFEN-GRWGKISARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQ-GSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDEFVRRVVEEVRKM--KVG--NPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEG--ATLVCGGNQVP-RPGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRVKTVTFEY-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R0Y6-1", "uniprot_id": "AL1L1_MOUSE", "id": "Q8R0Y6-1", "name": "Cytosolic 10-formyltetrahydrofolate dehydrogenase", "aln": "----------------------MKIAVIGQSLFGQEVYCQLR-KEGHEVVGVFTIPDKDGKADPLGLEAEKDGVPVFKFPRWRARGQALPEVVAKYQALGAELNVLPFCSQFIPMEVINAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFTIFWADDGLDTGDLLLQKECDVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGTAPRRPQPEEGATYEG-IQKKETAMINWDQPAEAIHNWIRGNDKVPGAWTEACG-----QKLTFFNSTLNTSGLVAQGEALPIPGAHRPGLVTKAGLILFGNDDRMLLVKNIQLEDGKMMPASQFFKGSA-SSALELTEEELATAEAVRSSWMRILPNVPEVEDSTDFFKSGAASVDVVRLVEEVKELCDGLELENEDVYMATTFGDFIQLLVRKLRGEDG---ESECVINYVEKAVKKLTLQMPYQLFIGGEFVDAEGAKTYSTINPTDGSVICQVSLAQVSDVDKAVAAAKEAFEN-GLWGKINARDRGRLLYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQ-GATIPINQARPNRNLTLTKKEPVGVCGIVIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNILPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCALSNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDQFVQKVVEEVGKM--KIG--NPLDRDTNHGPQNHEAHLRKLVEYCQRGVKEG--ATLVCGGNQVP-RPGFFFQPTVFTDVEDHMYIAKEESFGPIMIISRFADGDVDAVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRIKTVTFEY-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VIC9-1", "uniprot_id": "Q9VIC9_DROME", "id": "Q9VIC9-1", "name": "10-formyltetrahydrofolate dehydrogenase", "aln": "------------------MALKMRIAIIGQSNFAADVLELLLDRSNIQIVGVFTIPDKGSREDILATTATIHNIPVFKFACWRRKGVALPEVLEQYKSVGATLNVLPFCSQFIPMEVINGALLGSICYHPSILPRHRGASAISWTLIEGDEVAGFSIFWADDGLDTGPLLLTRQTNVESTDTLDTIYKRFLYPEGVKAMGVAVDMVASGTAPKIIQPEVGATYDPAMFKTENQVINLQATAEKIWNFVRGLDSVPGAIATVLHGNGTEEQIRLFGAHLYSAGPVSNGKVLRLRGLTKTAWIHSGGLLIEGTDGAFVNIRRIKR-GTKVISASEWFKQAEDQSITDFSEDELVKRSLLAGIWKAILK--EDVESSTDFFASGAGSMDVVRLVEEVKEAFD-VPLQNEQVFMAPVFEEFFSLLVRFLRQGSAGFGNQQLDFEAFTLKANKREIRVPTQLFINGEFVDAEAQRTLEIVNPTNEEVLCKVACASATDVDKAVRAAHSAFY--GSWRQITPRQRGQLMLNLADLMERNKEELATIESVDSGAVYTLALKTHVGMSIEAWRYFAGWCDKIQ-GNTIPVNPARPNNVLTFTRKEPIGVCGLITPWNYPLMMLSWKMAACIAAGNTCLIKPAQTCPLTALKFAELTVRAGFPPGVINVLPGKGSDAGQAVADHELVRKLGFTGSTPIGKHIMKSCADSNLKKCSLELGGKSPLIIFADCDMDKAVKHGMSSVFFNKGENCIAAGRLFVEDRIHDEFIRRVLKDLRTM--TIG--DPLDRSTAHGPQNHKAHFDKLLEFCRRGVDEG--AKLVYGGCRVPNLKGYFFTPTVFTNVTDDMFIAQEESFGPIMIISKFNGSDIDSLMQRANRTEYGLASGVFTKDIGKALNFADRIEAGTVFVNVYNKTDVAAPFGGFKQSGYGKDLGQEALNEYLKTKCVTVEY-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **...: . . **: : . .. *:* ** **: ** . * . * : .* *::..: **::*: : * : .: : :* ** ** * *** . * : *.*. . : ***:*: * ** .:. * . ::* *: .*: * .. * ..*:* **:*:: * * .* :: * : *:.****. :* : :.. :*:* :** **:.* :: * ::: *: .:: : *: * * .* :*.. :: ::: : * .*: ** :: . * : : . * *. **:* * : : ::* ***: : :* : : ** :** :.*:*.:: :* . : :* *::* **** * ** *:: *: .. * . * : .: ", "identical_positions": 111, "similar_positions": 136, "identity": "11.7%" }, { "cls_id": "homologset.agr.SGD:S000004781", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M7P8-1", "uniprot_id": "F1M7P8_RAT", "id": "F1M7P8-1", "name": "", "aln": "-----------------MRRTRRPRFVLMN-------KMDDLNLHYRFLNWR---------RRIREIREVRAFRYQERFKHILVDGDTLSYHGNSGEVGCYVASRPLTKDSNYFEVSIVDSG--VRGTIAVGLVPQYYSLDHQPGWLPDSVAYHADDGKLYNGRAKGRQFG---------SKCNSGDRIGCGIEPVSFDVQTAQIFFTKNGKRVGST----IMPMSPDGLFPAVGMHSLGEEVRLHLNAELGREDDSVMMVDSYEDEWGRLHDVRVCG---TLLEYLGKGKSIVDVGLAQARHPLSTRSHYFEVEIVDPGEKCYIALGLARKDYPKNRHPGWSRGSVAYHADDGKIFHGSGVG-------DPFGPRCYKGDIMGCG------IMFP--------RDYILDSEGDS----DDSCDTVILSPTARAVRNVRNVMYLHQ-----------------EGEEEEEEEEEEEDGEEIEQEHEGKKVVVFFTR---NGKIIGKKDAVVPSGGFFPTIGMLSCGEK-VKVDLHPLSG-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q9B3-1", "uniprot_id": "E9Q9B3_MOUSE", "id": "E9Q9B3-1", "name": "", "aln": "-----------------MRRTRRPRFVLMN-------KMDDLNLHYRFLNWR---------RRIREIREVRAFRYQERFKHILVDGDTLSYHGNSGEVGCYVASRPLTKDSNYFEVSIVDSG--VRGTIAVGLVPQYYSLDHQPGWLPDSVAYHADDGKLYNGRAKGRQFG---------SKCNSGDRIGCGIEPVSFDVQTAQIFFTKNGKRVGST----IMPMSPDGLFPAVGMHSLGEEVRLHLNAELGREDDSVMMVDSYEDEWGRLHDVRVCG---TLLEYLGKGKSIVDVGLAQARHPLSTRSHYFEVEIVDPGEKCYIALGLARKDYPKNRHPGWSRGSVAYHADDGKIFHGSGVG-------DPFGPRCYKGDIMGCG------IMFP--------RDYILDSEGDS----DDSCDTVILSPTARAVRNVRNVMYLHQ-----------------EGEEEEEEEEEEEDGEEIEQEHEGKKVVVFFTR---NGKIIGKKDAVVPSGGFFPTIGMLSCGEK-VKVDLHPLSG-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCJ5-1", "uniprot_id": "SPRY3_HUMAN", "id": "Q8NCJ5-1", "name": "SPRY domain-containing protein 3", "aln": "-----------------MRRTRRPRFVLMN-------KMDDLNLHYRFLNWR---------RRIREIREVRAFRYQERFKHILVDGDTLSYHGNSGEVGCYVASRPLTKDSNYFEVSIVDSG--VRGTIAVGLVPQYYSLDHQPGWLPDSVAYHADDGKLYNGRAKGRQFG---------SKCNSGDRIGCGIEPVSFDVQTAQIFFTKNGKRVGST----IMPMSPDGLFPAVGMHSLGEEVRLHLNAELGREDDSVMMVDSYEDEWGRLHDVRVCG---TLLEYLGKGKSIVDVGLAQARHPLSTRSHYFEVEIVDPGEKCYIALGLARKDYPKNRHPGWSRGSVAYHADDGKIFHGSGVG-------DPFGPRCYKGDIMGCG------IMFP--------RDYILDSEGDS----DDSCDTVILSPTARAVRNVRNVMYLHQ-----------------EGEEEEEEEEEEEDGEEIEPEHEGRKVVVFFTR---NGKIIGKKDAVVPSGGFFPTIGMLSCGEK-VKVDLHPLSG-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03212-1", "uniprot_id": "EAR1_YEAST", "id": "Q03212-1", "name": "Protein EAR1", "aln": "MSFKFLIESLLLGSISGQIRCGRSSVIPRGDVSYGGDDTDELNMDIMLFAFGTLIVVYIVICIVYFFTKQIATRLITAYYNEHGPGQRISLFSDYDENNAHVHSRRLMENMSLRWPNNLDDADEVRDKLAQLSPEEQFYYKQGEEYIKQNPPFLLNQGLLQQSEDSNPDTTREDPIMNEQTRQYIQEEGAYAWEFSPNPDMPNHTVIVENKTEVSFLNYNYDASISTNLPIPCINKVYYCEFKIFETDGPLNSDENVSKGVISFGLSTQPYPYFRLPGRHHHSIAYDSNGARRFNDSFKLNEQLRTLFPQCEKGDIVGIGYRSRSGTVFFTRNGKKLNEKSVGGHIRGWKFQYLYPIIGSNVPCQIHVNFGTYGFVYIEANVKKWGYAKSNGIKLPPPSYEDYGKDTLLESGGEDNDFDEDFSDGDSDNIAAGSTTNLNDDIIIRNGEILPPPPGFEFTMSPPTGKKIINEEINLDSLPMLPPSYSDDEHHSKNDKSAISGRIIGTSRNLITDEASFDSVDNDNEDENDHERDPEQFSEFDDYESRMHGI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *. .: . . *:**:. :: : : : : * * : : *: :* ..: .* ..:* ** * :: . . :*.. **..:* : : .: :: :. .: ::* * :.. .. : :: :. . . * . . : .:.:* ..*. .:*.: :*.:. * :. :. *. ::: * *: . .*: * : * .:* .: .: .: : .: : :**. * :. . : :: * .. . . .:: : : **.* ..:* :.:: * * :* :* :*:* *:. :* .* . :* :. *:.: : ::: *:: :** : :. : .:.. : : .*:***.. ::.. . * ::. . .*: : * . :* ", "identical_positions": 63, "similar_positions": 177, "identity": "11.45%" }, { "cls_id": "homologset.agr.SGD:S000004784", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CIT9-1", "uniprot_id": "SBSN_MOUSE", "id": "Q8CIT9-1", "name": "Suprabasin", "aln": "MYLVSLLSSCCLLVLLGTLPARAAHEDPVEKVIEGFSRGLSNAEREVGKALEGINNGITQAGREVEKIFGELSNMGSQAGKNVEHGLDKVAHDINNGIGHAGKEAEKFAHGVNHAAGQVGKETNKIIHHGVSQGGSEAGKFGQGSHHAFGQGGNVANKLGHETHHAFGQGGNVAHKLGHETHHAFGQGGNVADKLGHGGNVADKLGHGTHHAFGQGGNVADKLGHETHHAFGQGGNVADKLGHGTHHAFGQGGNVADKLGHETHHAFGQGGNVAEKLGHETHHAFGQGGNMADKFGQGAHHAFGQGGNMADKFGQGAHHAFGQGGNMADKFGQGAHHAFGQGGNMADKFGQGAHHAFGQGGNMADKFGQGAHHAFGQGGNMADKFGQGAHHAFGQGRDMAETFDQGAHHAFGQGGREGGRLVQGAGQGLSHAAKEAQQFGHGHGHGYYAAGQTWQEGDKVIHPGVSQAGEEMEQFGQGVRHTIKQAEKEAEKVAHGVQNGVNQAQKEAEKVAHGVQNGVNQAQKEAEKVAHGVQNGVNQAQKEAEKVAHGVQTGVNQAGKETQRVGQGVQTGFNQGQKEAEKVAHGVQTGVNQAGKETQKAGQGVNYAAGQAEKEAEKLGQGVHHAAGQEMNRLQQDVHNGVNQPSKEANQLLNGSHQGQGGYGGQHGGAATTTVVSGASVNKPFINFPALWRSIAATMP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18899-1", "uniprot_id": "DDR48_YEAST", "id": "P18899-1", "name": "Stress protein DDR48", "aln": "----------------------MGLFDKVKQFANSNNNNNDSGNNNQGDYVTKAENMIGED---------RVNQFKSKIGE---DRFDKMESKVRQQFSNTSINDNDSNNNDSYGS-----------NNNDSYGSNNNDSYGSNNNDSYGSNNNDS--YGSNNDDSYGSSNKKKSSYGSNNDDSYGSSNNNDS---YGSNNNDSYGSNNNDSYG--SNNDDSYGSSNKNKSSYGSNNDDSYGSNNDDSYGSSNKKKSSYGSSNNDSYG------------SNNDDSYGSNNNDSYGSNNDDSYGSSNKKKSSYGSNNDDSYG-SSNNNDSYGSNNDDSYGSSNKNKSSYGSSSNDDSYGSSNNDDSYGSSNKKKSSYGSNNDDSYGSNNDDSYGSSNKKKSSYGSSNNDSYGSNNDDS----------YGSSNKKKSSYGSNNDDSYGSS---------------------------------------NNNDSYGSNNDDSYGSSNRNKNSYGSSN-------------YGSSN-------NDDSYGSSNRGGRNQYGGDDDY----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * *::. :. ... ...:.: *. : :* * : .:.:: *: *: . :**: .:.: :.::. : :. :. .:.: ::. * *..: ..:*...:.::*...* : * :...::*...: . * :...::*...* . :*.* *. * ..:.::* .* *. * ..:: . *.* *. * ....::*...: .. * ..:.::* ::: . *.* *.:*.. ..::*...: ..:*.. ..::* ..* *.:*.. ..::*...: ..:*..::. ..* *.:*.. :: . *.* *.:*.. ..::*.... .::... :.::*... :. . : *: ..:* .:...* :: :: ::* :*. . ...: :* ::* .* :* .* : :. . . : * ** * : : ", "identical_positions": 69, "similar_positions": 247, "identity": "9.86%" }, { "cls_id": "homologset.agr.SGD:S000004788", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UXZ9-1", "uniprot_id": "KDM5A_MOUSE", "id": "Q3UXZ9-1", "name": "Lysine-specific demethylase 5A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MASVGPGGYAAEFVPPPECPVFEPSWEEFTDPLSFIGRIRPFAEKTGICKIRPPK---------DWQPPFACEVKT---FRFTPRVQRLNELEAMTR-----------VRLDFLDQLAKFWELQGSTLKIPVVERKIL----DLYALSKIVASKG------GFEIVTKEKKWSKVGSRLGYLPGKG---------------------------------------------TGSLLKSHYERILYPYELFQSGVSLMGVQMPDLDLKEKVEAEVLSTDIQPSPE---RGTRMNIPPKRTRRVKSQS--DSGEVNRNTELKKLQIFGAG----------------------------------PKVVGLAVGAKDKEDEVTRRRKVTNRSDAFNMQMRQRKG----TLSVNFVDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCL---LPPLPDVPKGDWRCPKCVAEECNKP-----REAFGFEQAVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGSGFPK---------------------------------------------------------------------------------KDGQRKMLPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVG---------MCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAP---------ELFESQPDLLHQLVT----------------------------------------------------IMNPNVLMEHGVPVYRTNQCAGEFVVTFPR-----------------------------AYHSGFNQGYNFAEAVNFCTADWLPIGRQCVNHYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVVMSEEEVFELVPDDERQCSACRTTCFLS-------------------------------ALTCSCNPERLVCLYHP-----TDLCSCPMQNKCLRYRYPLEDLPSLLYGVKVRAQSYDTWVNRVTEALSASFNHKKDLIELRVMLE---------DAEDRKYPENDLFRKLRDAVKEAETCGSVAQLLLSKKQKHRQSSDSGKTRTKLTVEELKAFVQQLVSLPCVISQTRQVKNLLDDVEEFHERAQEAMMDETPD--SSKLQMLIDMGSSLYVELPELPRLKQELQQARWLDEVRLTLS---DPQQVTLDVMKKLIDSGVGLAPHHAVEKAMAELQELLTVSERWEEKAKVCLQARPRHSMANLENIVN----------------EAKNIPAFLPNVLSLKEALQKAREWTAKVEAIQSGNNYAYLEQLESLSAKGRP------------------------------------------------------------------IPVRLDALPQVESQVAAARAWRERTGRTFLKKNSSHTLLQVLSPRTDIGVYGSGKNRRKKVKEIIEKEKEKDLDLEPLSDLEEGLEESRDTAMVVAVFKEREQKEIEAMHSLRA---------------------------ANLAKMTIVERIEEVKFCICRKTASG-FMLQCELCKDWFHNSCVPLPKSSSQKKGSSWQAKDVKFLCPLCMRSRRPRLETILSLLVSLQKLPVRLPEGEALQCLTERAMSWQDKARQALATDELSSALAKLSVLSQRMVEQAAREKTEKIISAELQKAAANPDLQGHLPSFQQSAFNRVVSSVSSSPHQTMDYDDEETDSDEDIRETYGYDMKDTASVKSSSSLEPNLFCDEEIPIKSEEVVTHMWTAPSFCAEHAYSSASKSCSQG------------SSTPRKQPRKSPLVPRSLEPPVLELSPGAKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDRFLHIMEDDSIEEKPLKMKGKDSSEKKRKRKLEKVEQLFGEGKQKTKELKKIDKPKKKKLKLNVDKSKELNKLAK----KLAKEEERKKKKEKAAAAKVELVKESTEKKRERKVLDIPSKYDWSGAEESDDENAVCAAQNCQRPCKDKVDWVQCDGGCDEWFHQVCVG-------------------------VSAEMAENEDYICINCAKKQGPDSPGQAPPPPFLMSYKLPMEDLKETS--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A096MJZ8-1", "uniprot_id": "A0A096MJZ8_RAT", "id": "A0A096MJZ8-1", "name": "Lysine-specific demethylase 5A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MAGVGPGGYAAEFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPK---------DWQPPFACEVKT---FRFTPRVQRLNELEAMTR-----------VRLDFLDQLAKFWELQGSTLKIPVVERKIL----DLYALSKIVASKG------GFEIVTKEKKWSKVGSRLGYLPGKG---------------------------------------------TGSLLKSHYERILYPYELFQSGVSLMGVQMPDLDLKEKVEAEVLSTDIQPSPE---RGTRMNIPPKRTRRVKSQS--DSGEVNRNTELKKLQIFGAG----------------------------------PKVVGLAVGAKDKEDEVTRRRKVTNRSDAFNMQMRQRKG----TLSVNFVDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCL---LPPLPDVPKGDWRCPKCVAEECNKP-----REAFGFEQAIREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGSGFPI---------------------------------------------------------------------------------KDGQRKMLPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVG---------MCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAP---------ELFESQPDLLHQLVT----------------------------------------------------IMNPNVLMEHGVPVYRTNQCAGEFVVTFPR-----------------------------AYHSGFNQGYNFAEAVNFCTADWLPIGRQCVNHYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVVMSEEEVFELVPDDERQCSACRTTCFLS-------------------------------ALTCSCNPERLVCLYHP-----TDLCSCPMQNKCLRYRYPLEDLPSLLYGVKVRAQSYDTWVNRVTEALSASFNHKKDLIELRVMLE---------DAEDRKYPENDLFRKLRDAVKEAETCGSVAQLLLSKKQKHRQSSDSGKTRTKLTVEELKAFVQQLVSLPCVISQTRQVKNLLDDVEEFHERAQEAMMDETPD--SSKLQVLIDMGSSLYVELPELPRLKQELQQARWLDEVRLTLS---DPQQVTLDVMKKLIDSGVGLAPHHAVEKAMAELQELLTVSERWEEKAKVCLQARPRHSMANLENIVN----------------EAKNIPAFLPNVLSLKEALQKAREWTAKVEAIQSGSNYAYLEQLESLSAKGRP------------------------------------------------------------------IPVRLDALPQVESQVAAARAWRERTGRTFLKKNSSHTLLQVLSPRTDIGVYGSGKNRRKKVKEIIEKEKEKDLDLEPLSDLEEGLEETRDAAMVVAVFKEREQKEIEAMHSLRA---------------------------ANLAKMTIVDRIEEVKFCICRKTASG-FMLQCELCKDWFHNGCVPLPKSGSQKKGSSWQAKDVKFLCPLCMRSRRPRLETILSLLVSLQKLPVRLPEGEALQCLTERAMSWQDRARQALATDELSSALAKLSVLSQRMVEQAAREKTEKIISAELQKAAANPDLQGHLPSFQQSAFNRVVSSVSSSPHQAMDYDDEETDSDEDIRETYGYDMKDTASVKSSSSLEPNLFCDEEIPIKSEEVVTHMWTAPSFCAEHAYSSASKSCSQG------------SSTPRKQPRKSPLVPRSLEPPVLELSPGAKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDRFLHIMEDDSVEEKPLKMKGKDSSEKKRKRKLEKVEQFFGEGKQKTKELKKIDKPKKKKLKLNVDKSKELNKLAK----KLAKEEERKKKKEKAAAAKVELAKESTEKKRERKVLDIPSKYDWSGAEESDDENAVCAAQNCQRPCKDKVDWVQCDGGCDEWFHQVCVG-------------------------VSPEMAENEDYICINCAKKQGPDSPGHAPPPPFIMSYKLPMEDLKETS--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29375-1", "uniprot_id": "KDM5A_HUMAN", "id": "P29375-1", "name": "Lysine-specific demethylase 5A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MAGVGPGGYAAEFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPK---------DWQPPFACEVKS---FRFTPRVQRLNELEAMTR-----------VRLDFLDQLAKFWELQGSTLKIPVVERKIL----DLYALSKIVASKG------GFEMVTKEKKWSKVGSRLGYLPGKG---------------------------------------------TGSLLKSHYERILYPYELFQSGVSLMGVQMPNLDLKEKVEPEVLSTDTQTSPE---PGTRMNILPKRTRRVKTQS--ESGDVSRNTELKKLQIFGAG----------------------------------PKVVGLAMGTKDKEDEVTRRRKVTNRSDAFNMQMRQRKG----TLSVNFVDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCL---IPPLPDVPKGDWRCPKCVAEECSKP-----REAFGFEQAVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGSGFPV---------------------------------------------------------------------------------KDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVG---------MCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAP---------ELFESQPDLLHQLVT----------------------------------------------------IMNPNVLMEHGVPVYRTNQCAGEFVVTFPR-----------------------------AYHSGFNQGYNFAEAVNFCTADWLPIGRQCVNHYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVLMSEEEVFELVPDDERQCSACRTTCFLS-------------------------------ALTCSCNPERLVCLYHP-----TDLCPCPMQKKCLRYRYPLEDLPSLLYGVKVRAQSYDTWVSRVTEALSANFNHKKDLIELRVMLE---------DAEDRKYPENDLFRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQLFSLPCVISQARQVKNLLDDVEEFHERAQEAMMDETPD--SSKLQMLIDMGSSLYVELPELPRLKQELQQARWLDEVRLTLS---DPQQVTLDVMKKLIDSGVGLAPHHAVEKAMAELQELLTVSERWEEKAKVCLQARPRHSVASLESIVN----------------EAKNIPAFLPNVLSLKEALQKAREWTAKVEAIQSGSNYAYLEQLESLSAKGRP------------------------------------------------------------------IPVRLEALPQVESQVAAARAWRERTGRTFLKKNSSHTLLQVLSPRTDIGVYGSGKNRRKKVKELIEKEKEKDLDLEPLSDLEEGLEETRDTAMVVAVFKEREQKEIEAMHSLRA---------------------------ANLAKMTMVDRIEEVKFCICRKTASG-FMLQCELCKDWFHNSCVPLPKSSSQKKGSSWQAKEVKFLCPLCMRSRRPRLETILSLLVSLQKLPVRLPEGEALQCLTERAMSWQDRARQALATDELSSALAKLSVLSQRMVEQAAREKTEKIISAELQKAAANPDLQGHLPSFQQSAFNRVVSSVSSSPRQTMDYDDEETDSDEDIRETYGYDMKDTASVKSSSSLEPNLFCDEEIPIKSEEVVTHMWTAPSFCAEHAYSSASKSCSQG------------SSTPRKQPRKSPLVPRSLEPPVLELSPGAKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDRFLHIMEDDSMEEKPLKVKGKDSSEKKRKRKLEKVEQLFGEGKQKSKELKKMDKPRKKKLKLGADKSKELNKLAK----KLAKEEERKKKKEKAAAAKVELVKESTEKKREKKVLDIPSKYDWSGAEESDDENAVCAAQNCQRPCKDKVDWVQCDGGCDEWFHQVCVG-------------------------VSPEMAENEDYICINCAKKQGPVSPGPAPPPSFIMSYKLPMEDLKETS--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IQX0-1", "uniprot_id": "KD5BB_DANRE", "id": "Q6IQX0-1", "name": "Lysine-specific demethylase 5B-B", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MTQQGP----AEFTPPPECPVFEPSWEEFKDPFAFINKIRPIAEKTGICKVRPPP---------DWQPPFACDVDR---LHFTPRIQRLNELEAQTR-----------VKLNFLDQIAKFWDLQGCTLKIPHVERKIL----DLYQLNKLVADEG------GFDLVCRERRWTKIAMTMGFAPGKA---------------------------------------------VGSHLRAHYERILYPYNLFQSGTNLL-CLQKPGDEVNDIDKEYKPHDLLQRQNVPLQPSNTSAPARRAKRMKTESGCIKSEEGEGVENKPNLRRRMG----------------------------------SFVVKTEPK--KEIPIQVKEEPVEIKELNPEPEKSKPKKKNIPPPPVSMVDLYVCLVCGKGNDEDRLLLCDGCDDSYHTFCL---IPPLTDVPKGDWRCPKCLTQECCKP-----QEAFGFEQAHRDYTLKAFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVGTIQEDVTVEYGADIASKEFGSGFPI---------------------------------------------------------------------------------KGGRFKIAPHDEKYLQCGWNLNNMAMMTPSVLTHVTADICGMTLPWLYVG---------MCFSSFCWHIEDHWSYSINYLHWGEPKTWYGAPGFAAEQLEAVMKKLAP---------ELFDSQPDLLHQLVT----------------------------------------------------IMNPNTLMAHGVPIYRTNQCAGEFVITFPR-----------------------------SYHSGFNQGFNFAEAVNFCTVDWMPLGRQCVDHYRQLHRYCVFSHDEMVCNMAMKADCLDVVLASAVQKDMQLMIKEERELREKVRKMGVAQCELFQYDLLADDERQCVKCRTTCYLS-------------------------------ALTCPCRPGVQVCLYHT-----HDLCSCPISNYTLNYRFTLDDLYPMMNAVRQRAEYYDDWASRVTEVMEAKLDKKRNVTVFRTLLE---------ESNEQSFPENDLLRQLRLVTQDAEKCSSVAQQLLNGKRQTRYRTGKAKSPNQLTVEEMRSFVRQLYNLPCSLTQAPLLKELLNSIEDFQQHSEKLLSDEVSADAVSEIESLLEEGSQFDVFLPELPLLRERLEQARWLTGVHQAEDPVANPCGLSLESMRRLIDRGVGLTPHPSIERMMARLQELLTVSEELEENAQALLKARPPESLETLCSMLT----------------QVEGVPAYLPNCLLLQDTVNRAKEWLQEAESLQVGGQVPVFSSLSDMVLRAHS------------------------------------------------------------------IPVRLEPLDQLEVQVSEVQSWKETAAKTFLIKSSPFTLLEVLCPRWEMGSSLKKKKMRKMKGDCVSSGKKKFVKLDSMSDVERALSDSKDSASAMFTLAEVRLKELESLCSLRA---------------------------SNESKLLPTADCASLKVCVCQKPAMG-AMLQCELCRDAFHSVCVRGPSD---------PLDPEAWLCPLCLRSTKPPLDKIRSLLSSLQRIRVRLPEGDALRYMIERSVSWQRRVREVIDSYGLSSTSQDG---------------------------------------------------------------------------------------------------------RGASPSQNLYRSTGHSRKLQLCGSPSRCQDW------------AVSGQEQ---TVFYTEQRCIPLQGLSP----ELEELMVEGLVLQVSLPETQQLYRLLLS--GPPTT------NTSHAEHKSYLTPPQTETDAITS-------------------AEKKAKRRMNRDEVD--IRERGTKLKS----KKQRMMGVEKRRERKAASVS--ASDMSQ------------------SEDSEEDMTLCPAESCLQPEGEEVDWVQCD-CCNRWFHMICVG-------------------------VSAELAAEEDYMCVSCSTSHMDRRK-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q713-1", "uniprot_id": "A0A8M9Q713_DANRE", "id": "A0A8M9Q713-1", "name": "[histone H3]-trimethyl-L-lysine(4) demethylase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MTHSRP----NEFIPPPECPVFEPSWEEFADPFGFINKIRPIAENTGICKIRPPP---------GWQPPFACDVDR---LHFTPRIQRLNELEAQTR-----------VKLNFLDQIAKFWELQGCTLKIPHVERKTL----DLFVLYKLVKEDG------GFDVVCKERRWTQIALKMGFAPGKA---------------------------------------------IGSHLRAHYERILYPYYLFQTGANLMQNSQKPTLTNDTKDKEYKPHDLPQRQ--SVQPVETCTIARRAK--RTEGRCFKSEPGEVCENKPNLRRRMG----------------------------------SYVAKPEPGTFKMLPVQVKEEPIVQPVDG---EKSK-------------VEQYICLVCGGGGDEDRLLLCDGCDDSYHTFCL---IPPLHDVPKGDWRCPKCLAQECGKP-----QVAFGFEQAPRDYTLRTFGDMADSFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKDFGSGFPV---------------------------------------------------------------------------------KNGTFKVSPEEEGYLTSGWNLNNMPVLEASVLTHVTADICGMKLPWLYVG---------MCFSSFCWHIEDHWSYSVNYLHWGEPKTWYGAPGYAAEQLEDVMKSLAP---------ELFESQPDLLHQLVT----------------------------------------------------IMNPNLLMEHGVPIYRTNQCAGEFVITFPR-----------------------------AYHSGFNQGFNFAEAVNFCTADWLPLGRQCVEHYRSLYRYCVFSHDEMACNIAAKADSLELELACAVQKDMNAMIQEEKILREKAYKLGMWHSQQVDYDILPDEERQCAKCRTTCYLS-------------------------------AITCPCSPEQVVCLHHT-----QDLCSCPARNYTLNYKYTLAELKTFFQALTARAESYDDWASKVNKILKADQDNKSDLEELRCLLA---------EAEKKMYPETDLLNDMRQVIQNADRCTIMAQQLLNGKRQTRYRSGGGKSQNQLTVEELRAFVNKLYDLPCTIRQAPFLKALLNRVEQFQQQSFDMLAEDMAG--SSALQGLLDEGAGLDVELPQLAVLRQRLEQARWVEAVQEASD---QPADLSLDCMRRLIDQGVGLAPHVCVERTMARLQELLTVCEHWEEKAHNMLTARPRHSIETLEAAIL----------------EVDSIPAYLPSCLQLKDCVSRAREWIMEADALQAGGRIPGLVTLSELVSRAKG------------------------------------------------------------------IPVMLEALTRLESLISEVQAWKESAAKTFLLRNSSLSLLEVLCPRCETGS--QKSKSKKAKEGLVP-CKKADVKLDSLFDVEKVLSTSKDTASAMATLSDVHQKELDSLSMLRT---------------------------SNESKFQSSPSCLAPTVCLCHTVPAG-PMLQCELCRDAYHSGCVPGFKD---------IQIGQPWLCPLCKRSEKPPLDKVLPLLASLQRIRVRLPEGDALRYVIERTVRWQHKVQQVS----LPTLHPNG---------------------------------------------------------------------------------------------------------KARHIS-------GFTSSQTLEGSNS----------------------------SFYMLQPCIPLSELSA----ELEELLVEGLLLQVTLPELQQLYSSLINRFSPSQH------SLQSSEHDHQYHIAQDRSPPHRSPSHSKGQDAVPEIKKEHEKLEKNSKRRLEKEITEGQYRDKIKKPKK----KKPKMIKERRREEKRTTSPSNSLSDPSN------------------SDDSEEDWSVCSAKRCQQPEGNEVNWVQCDGSCNQWFHQVCVG-------------------------VSAEQAENEDYICVSCAINDLSE---------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03214-1", "uniprot_id": "ECM5_YEAST", "id": "Q03214-1", "name": "Protein ECM5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MSGHDSVTKISHILNEP-VNEKVMVQNGFHESSKIADIELEIQERPSIKQWESPRSAVIPTSNHNFSPFLYTQFKSRGAAPFAPETIKSVDLVELPEGV---------PARVFHEKTGLFYQISPHSIPTFILAKKELP---DPIKFYELVEDLGSVYGCVKLKIIPDADKFTQLNVDVDRLWFKARK---------------------------------------QFFNSNEFQRTKIVDFYAKLYNFHNKIKKSTLTRIPSIDKRTLDLYRLRSCVKLRGG-FNAVCEKKLWAQIGRELGYSGRIMSSLSTSLRSAYAKILLDFD----------------------------------IYEEEEQAARNNEKNEDMVESEIFRHSNSRSRDEEEPLHKKAKIHRDVFRAGSINHEFKRMRDIKHIKGFPTYFNSLTEFKLGYTQSTETTLPGYDFTFWENGMEIYDKSKYETKTSPVYNLRQYYEKSLAVFTAIVAKFGSSYP--DLFAKHTTLPQKEFERLYFHLLSEHFIDFEIDTG-LGLPCSMRS---------------------------------------------------------------------------------PGNNSSNEKFAIKNILDQWNLDNIPLNELSLLQHLDLDMANFTRTTYDIG---------MLFSCQGWSVSDHFLPSIDFNHLGSTKLVYSIAPKDMEKFEALIARGKSEWDTIQ-SRPRYSTSDDELKSFIETDFYKSFLDAEQS-------ADYSNTGDNSKNSFPEDKIAGNTLHDGSQSDFIFEPNFILANGIKLYKTTQEQGSYIFKFPK-----------------------------AFTCSIGSGFYLSQNAKFAPSSWLRFSSEAAKWTSKMGFLPGLDVNQLLINALLNSNNPVLRKKCRDLISNYVVEEAENSKKLGELIGTVDVVYNKLNYISDISLESTGLSKIVVTHG-------------------------------ALQRNLSLKEFVVLLEKPENGAHSICGIPIRDQSGNLNVCLHSYFDSAS-LGIALDGLDKPPTSYLLVHNEDFEKKWDVLMTSTFRN---------RTVP--------LNIIQYLISHTDSNTEFNRMLRSN-----------FDDSLLLIEKCKKFIKTFVDVSCSVKDVDFGNGFN--LRHLPLKFSDNMADNLES--------LYESVRKCSIEFSEKPTIIRLYHVSRQFPIDNRDIID-GNNLDLLKELYQKSLTIPLKVSYWTKLTRKICRLEWLSVYEHIFIERCDIKNEDPAKYSLPLLYSYFEF-------GLKYCDSEDIDKLGEVRKLILKYQDMMQKVRVFLKKDPPSKISLSDLEDVLLDIEEYR---------------------------------------------------------------------LPIQSSFFSELDYVIREIENAKKMNDVNILYNTDNIDKIDELIRKNDPKFVKFANQFNGSRLDKRPLASDNSGSVKAKQELKVFKLWNQHLDQIMQKNKFIEILPSIFRCLDLK---------------------------SDKYIPLESCSKRQTKYCFCRRVEEGTAMVECEICKEWYHVDCISNGELVPP------DDPNVLFVCSICTPP-CMAVDNIEGVTFELDDLKRILVES-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKLSLIPDPPILKNLFDVFAFALN----------------------------------------------------FKNEMEKELFTNGYVNQLSSTHK----IKYYLRKLKG------------------------------------SQCGFTNLTDPLRKHCQVKDAEAIKWLTDN------GRIIITG-------------------------IPN-----------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VT00-1", "uniprot_id": "JARD2_DROME", "id": "Q9VT00-1", "name": "Jumonji, AT rich interactive domain protein 2", "aln": "MVVSKDNNKRRRKETETPPPPPPVPPAGSSLAPPSAVAAIESSPEMPKRTKVQAQRKFAQGQSAPSSSSSIAYSAAAAAAGSGSGPSTSGADSNQPPIEILPNKCPKPQDFLTFLCFRGTRALPAHLDFLNQGKSKDSEASSTGANNNNNARKPNNSRASLAGNKKKRGRPAKGATKKVDVVAPIPDPTEKPSTAEKPASDKNNLIAAEAPKIPSRNPTPVLPGAVRKRAEVVTDGNRRGARGRGAGISHDKTTPAALSKDNKRRSNRASTKESKPVIDDDNSEDLDEQEADDDEDEFFSAHDATSRNGEEVKADSPVKAEPTKRGRPSAAKKAVEPAPEGQTVLKDKAPVKRVRQRESPIFIPSPESSGRMTRQRAFFEPVKVPPHKEEPGAHDPPKDEPKKQPETPPSKTEKEQEPTKQIKEAKEKTNSSIYAKEAKQQLENGDSLHGAVAKGKKSLNVFDFSSDDEQPLAKSIKLKKGAKGASPKKGGAAPIAPAARNRKAAAKKLDKEKEIEKEKQREKEEEIERDKAKEKKDKEKEKEKEKHPVPESKVEEPPSGGKRGKAGKKKAEDAPADEEDLAPPSSKKVATNARGSRKSAKSKASEDSAELEPQRSQRPSRKTKEAAAIYMGIIGHKLQLADDEEDDLSMSSFPDIPNVKEMEKMENEIKRNAAGKLNVPEASTVLSAGKSTRKPSPRPKDSPVTAPVEATRNESPSPPEAEEEKPPPPARRGRPPKQNKVNAGPAHKPRIEGMLVKKGSLAKMSEQQAKPKAKSEHSKVDSDEEEDFLINEELNETKRKLEKSFSDSDDEPLAIKVPAVAVKEKELLPPKMASPPPKLVPVPSPISVPTPAVSVAPSLAVPSILPTSTGTTQLTMLPLTAKATSSLGSMPMFPSIQASYSPLKTMEKKPPVPTSKILNVPATYALPGSASGAVSFQKTSSYLPQASPHYHSGYVRPPPTPTHQFGGGAPSGSKTPSQGSSPLKYQTPPTTYPPPIEAYQCPKINPNFLTPKYERSPLPRSSTSSFPSPSPVKFQPTSGTTATTVGTPSSATKSPLAPPPPSPPVSQVVIQTSSLNLSMSIAATVNAAPMPVASTSAAAAHQTTVATTVTATSTPPPAHSNSAATGGGAGANSDPLKDEIGSILAQATLMPSKEESGKIFGIASVSLAQSSGPDNTKCTLGKCG-SIHKPVLGPVVPTEGYFGDQLSSKERRKAKVNMTHEQIQKWLIECSSNPDEIQDDLDDDFDDSLRPQQSTTPPPTRDDKELSASFSSSSKNTRGDLGKSESAWSAKGPSLKATPVLVTPPNRKELHEQADSKDCDALDYDKSSTPVNLTQKITSNESLAVEKKVNDRKGKESAKAAASKAATQPRSTAATPPTPISSTPTPASLTPSKSSPTPPPAVKQKAEK-GKRNATAGGGATALASPPAAPTPANPKRTPVYNQKNAKAQQQQAETKPASNPPSGAGTKRESVYAFGKDDESGSKSGNRRRTDPSPVPAPALVPNALSERSPTKKRAAAAAAATAVQLTLSPTENCKIEGKPSKAPTGRGAKKQQQQAPAPPAPPVEASGDSDAEGATFYIPLQGAGVGGSGDGGIQGVAVKLGREGPDGPNQKVVMQATLVTKAQMDTNSKPLPESLNTNELVKTLLHAASNDAASTTTSLKSLPKASTSAAAGAAAAPGASSLVRVNSNSSLFSGSAKSRTAAQTSSTAAAVAKKYKDDTPIKMANNTAFPRHDDPTQMVEAPIFRPTEKEFADPIEFIERITPIAARFGICKIIPPASFKPECRISDEMRFTAYNQYVHKMLHRWGPSAKELSAIKKYLATQSIVMNHPPWIGGMEVDLPRLYHTVQELGGLKEVIEKKKWARVAEEMCIPKLAQDRVTKLDDIYCKYLLPYDTLSPAERQKLFDEVEADWAKREARARRNADRFVNTESVSNEEDDLSSDEDEESEEEIDGVSMECIVKGRSMPLSQFYRIARNTMALWFKSTDPTVNEVEAEFWRHVAVRDSHVCVHSGSIDSSGWGYGFPSPGPKGKGSNYARHPWNLKVLTNNSGSVLRSLGPVMGVTVPTLHVGMLFSACCWYRDPHGLSWIEYLHTGASKLWYGIPDDQSANFRAALTSLIPTHCQNKTIWLPCDTVMVPPHMLTDRGVSLCRIEQKPGEFIVVFPRAYTSSLATGYVVSESVYFATMSWLDLAKDDFRDIHESCEPAMFSLEQLLFALGYDQRVNSEALHQMLPMLNDVCEKESAAREQLRAAGVTSTEKVQAEKGQKAKKQQQPPYKSIESECDLCRANLYISMVRTEDGNIYCLQHALKNLNNGNIQAKQCKLIYAYNVDDIQQLIRQLQEKINHKAAVKKK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . . ... . . .. . * : . : . : * : : : : . . . . : : * :: . . . . .: : .. . . . . . : . . . : . : : . : : : .. : **: :: : : . . : .. . . :*:: . : . : :. . : . : . . . . . : : . : : : *. : * .. *. ..: . . ..: .. .:* . . . . : ... : . : . . . :: . * * . : : : . :. : . : .:: . :. : . . : : : ... : . . . . : . . . : : . : . . . . . : . * :. .: . : :. : : : . : . * .. : . . :.. .: .: :: .*: . :*.:. : . : : .* : : * : . . .. . . . : . * . . : :. ", "identical_positions": 19, "similar_positions": 231, "identity": "0.81%" }, { "cls_id": "homologset.agr.SGD:S000004795", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61265-1", "uniprot_id": "STX1B_RAT", "id": "P61265-1", "name": "Syntaxin-1B", "aln": "-MKDRTQELRSAK-DSDDE-EEV-VHVD-------------RDHFM------DEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEG-LNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGR-TTTNEELEDMLESGK-LAIFTDDIKMDSQMT--KQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMII--ICCVVLGVVLASSIGGTLGL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61264-1", "uniprot_id": "STX1B_MOUSE", "id": "P61264-1", "name": "Syntaxin-1B", "aln": "-MKDRTQELRSAK-DSDDE-EEV-VHVD-------------RDHFM------DEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEG-LNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGR-TTTNEELEDMLESGK-LAIFTDDIKMDSQMT--KQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMII--ICCVVLGVVLASSIGGTLGL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35526-1", "uniprot_id": "STX1A_MOUSE", "id": "O35526-1", "name": "Syntaxin-1A", "aln": "-MKDRTQELRTAK-DSDDD-DDVTVTVD-------------RDRFM------DEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEG-LNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGR-TTTSEELEDMLESGN-PAIFASGIIMDSSIS--KQALSEIETRHSEIIKLETSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMII--ICCVILGIIIASTIGGIFG---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32851-1", "uniprot_id": "STX1A_RAT", "id": "P32851-1", "name": "Syntaxin-1A", "aln": "-MKDRTQELRTAK-DSDDD-DDVTVTVD-------------RDRFM------DEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEG-LNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGR-TTTSEELEDMLESGN-PAIFASGIIMDSSIS--KQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMII--ICCVILGIIIASTIGGIFG---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16623-1", "uniprot_id": "STX1A_HUMAN", "id": "Q16623-1", "name": "Syntaxin-1A", "aln": "-MKDRTQELRTAK-DSDDD-DDVAVTVD-------------RDRFM------DEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEG-LNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGR-TTTSEELEDMLESGN-PAIFASGIIMDSSIS--KQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMII--ICCVILGIVIASTVGGIFA---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24547-1", "uniprot_id": "STX1A_DROME", "id": "Q24547-1", "name": "Syntaxin-1A", "aln": "MTKDRLAALHAAQSDDEEE-TEVAVNVDG------------HDSYM------DDFFAQVEEIRGMIDKVQDNVEEVKKKHSAILSAPQTDEKTKQELEDLMADIKKNANRVRGKLKGIEQNIEQEEQ-QNKSSADLRIRKTQHSTLSRKFVEVMTEYNRTQTDYRERCKGRIQRQLEITGR-PTNDDELEKMLEEGN-SSVFTQGIIMETQQA--KQTLADIEARHQDIMKLETSIKELHDMFMDMAMLVESQGEMIDRIEYHVEHAMDYVQTATQDTKKALKYQSKARRKKIMIL--ICLTVLGILAASYVSSYFM---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q64704-1", "uniprot_id": "STX3_MOUSE", "id": "Q64704-1", "name": "Syntaxin-3", "aln": "-MKDRLEQLKAKQLTQDDDTDEVEIAID-------------NTAFM------DEFFSEIEETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDE---VRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGK-KTTDEELEEMLESGN-PAIFTSGII-DSQIS--KQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKRAMKYQGQARKKLIIII--VVVVVLLGILALIIGLSVGLK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08849-1", "uniprot_id": "STX3_RAT", "id": "Q08849-1", "name": "Syntaxin-3", "aln": "-MKDRLEQLKAKQLTQDDDTDEVEIAID-------------NTAFM------DEFFSEIEETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDE---VRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGK-KTTDEELEEMLESGN-PAIFTSGII-DSQIS--KQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKRAMKYQGQARKKLIIII--VIVVVLLGILALIIGLSVGLK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00262-1", "uniprot_id": "STX2_MOUSE", "id": "Q00262-1", "name": "Syntaxin-2", "aln": "-MRDRLPDLTACRTNDDGD-TAVVI-VE-------------KDHFM------DGFFHQVEEIRSSIARIAQHVEDVKKNHSIILSAPNPEGKIKEELEDLDKEIKKTANRIRGKLKSIEQSCDQDEN-GNRTSVDLRIRRTQHSVLSRKFVDVMTEYNEAQILFRERSKGRIQRQLEITGR-TTTDDELEEMLESGK-PSIFISDIISDSQIT--RQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMVNNIERNVVNSVDYVEHAKEETKKAIKYQSKARRKKWIIA--AVAVAVIAVLALIIGLSVGK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50279-1", "uniprot_id": "STX2_RAT", "id": "P50279-1", "name": "Syntaxin-2", "aln": "-MRDRLPDLTACRKSDDGD-NAVIITVE-------------KDHFM------DAFFHQVEEIRSSIARIAQHVEDVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANRIRGKLKAIEQSCDQDEN-GNRTSVDLRIRRTQHSVLSRKFVDVMTEYNEAQILFRERSKGRIQRQLEITGR-TTTDEELEEMLESGK-PSIFISDIISDSQIT--RQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMVNNIERNVVNSVDYVEHAKEETKKAIKYQSKARRKKWIIA--AVVVAVIAVLALIIGLTVGK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2BEN6-1", "uniprot_id": "A0A8M2BEN6_DANRE", "id": "A0A8M2BEN6-1", "name": "", "aln": "-MRDRLADLNVGRHNASED-GGVAVSME-------------RNDFM------QDFFQKVEEVRRVIEKISSLVDEVKKKYSVILSAPNPDEKTKEELEQLTVEIKKHANYVQKSLKSMHQSLPSDEQ-VNQASVDARIQKTQYTNLSHKFVEVMTQYNEAQVSFREKSKSRIQRQLEITGK-ITTNEELEEMLETGN-PSIFTSDIISDSQIT--RQALNEIESRHQDILRLESSIKELHDMFVDMAMLVETQGEMIDNIEKNVHNAVEYVGQAKVETKKAVRYQTRARR-KWVYG--AICGAVCIIILLLIIITAVYVD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1PT03-1", "uniprot_id": "A0A8M1PT03_DANRE", "id": "A0A8M1PT03-1", "name": "Syntaxin-1A", "aln": "-MKDRTQELRHGKELEEQNEVTMNNKMVI------------EDGFM------DEFFEQVEEIREFIDSLAEKVGEVKRNHSATLASPNPDEKTKTEFEELMNDIKTLANKVRSRLQHIQQSIEHEEA-FNGQSADVRIRKTQHSTLSRKFVEVMSEYNAAQSEYRERCKGRIQRQLEITGR-KTTKEELETILESDN-PSIFTTGVFMDCSIT--KQAMNEIETRHNEIIQLESCIRELQDMFVDLAVLVENQGELINNIETNVSSAQEYVEKAKEETKAAIKIQKTSRTKLILIGGCVSVCVLILIIALIFGLT-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P70452-1", "uniprot_id": "STX4_MOUSE", "id": "P70452-1", "name": "Syntaxin-4", "aln": "-MRDRTHELRQGDNISDDE-DEVRVALVV------------HSGAARLGSPDDEFFQKVQTIRQTMAKLESKVRELEKQQVTILATPLPEESMKQGLQNLREEIKQLGREVRAQLKAIEPQK-EEAD-ENYNSVNTRMKKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSGQ-SEVFVSNILKDTQVT--RQALNEISARHSEIQQLERSIRELHEIFTFLATEVEMQGEMINRIEKNILSSADYVERGQEHVKIALENQKKARKKKVMIA--ICVSVTVLILAVIIGITITVG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08850-1", "uniprot_id": "STX4_RAT", "id": "Q08850-1", "name": "Syntaxin-4", "aln": "-MRDRTHELRQGDNISDDE-DEVRVALVV------------HSGAARLSSPDDEFFQKVQTIRQTMAKLESKVRELEKQQVTILATPLPEESMKQGLQNLREEIKQLGREVRAQLKAIEPQK-EEAD-ENYNSVNTRMKKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSGQ-SEVFVSNILKDTQVT--RQALNEISARHSEIQQLERSIRELHEIFTFLATEVEMQGEMINRIEKNILSSADYVERGQEHVKIALENQKKARKKKVMIA--ICVSVTVLILAVIIGITITVG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1Q0-1", "uniprot_id": "STX19_MOUSE", "id": "Q8R1Q0-1", "name": "Syntaxin-19", "aln": "-MKDRLQELKQKTKEIELSRDGQVFVEE------EQGVLVQQAVIYEREPVAERHLHEIQKLQENINSFVDDVQRFGQQQKSLVASMRRFSLLKRDS-TIAKEIKIQAEHINRALGDVVKEVKKSEVENGPSSVVTRILKSQYAAMFRRFQQTMFLYNDTIALKQEKCKTFIVRQLEVAGK-EVSEEEVNDMLHHGK-WEVFNESLLTETSIT--KAQLSEIEQRHKELVNLENQVKDLRDLFIQISLLVEEQGESINSIEVMVNSTKDYVNNTKEKFGLAVKYKKRNPCRALCCCCCPRCGSK----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ASN7-1", "uniprot_id": "A0A8I6ASN7_RAT", "id": "A0A8I6ASN7-1", "name": "Syntaxin-19", "aln": "-MKDRLQELKQKTKEIELSRDSQVFAEE------EQGVLVQQAVIYEREPVAERHLHEIHKLQENINSFVDDVHRFGQQQKSLVASMRRFSLLKRDS-TITKEIKLQAEHINRALGDVVREVKKSEVENGPSSVITRILKSQYAAMFRRFQQTLFLYNDTIALKQEKCKTFIVRQLEVSGK-EVSEEEVNDMLHHGK-WEVFNESLLTETSMT--KAQLSEIEQRHKELVNLENQVKDLRDLFIQISLLVEEQGESINNIEVMVNSTKDYVNNTKEKFGLAVKYKRKNPCRALCCCCCPCCGSK----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N4C7-1", "uniprot_id": "STX19_HUMAN", "id": "Q8N4C7-1", "name": "Syntaxin-19", "aln": "-MKDRLQELKQRTKEIELSRDSHVSTTETE----EQGVFLQQAVIYEREPVAERHLHEIQKLQESINNLADNVQKFGQQQKSLVASMRRFSLLKRES-TITKEIKIQAEYINRSLNDLVKEVKKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGK-EMSEEDVNDMLHQGK-WEVFNESLLTEINIT--KAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLVEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRNPCRVLCCWCCPCCSSK----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AVX8-1", "uniprot_id": "A0A8M3AVX8_DANRE", "id": "A0A8M3AVX8-1", "name": "", "aln": "-MKDRMEELRQQMKASEKLVDSKPFNKEEDEDMDPSSLIGLQAVIFEAEPVLEIFLKDAQGIRDSIEELNSEVSKFNEQQKNFVATMRRLSIMKKES-NMTRDIKLLAESLHKRLDALSKQAKQTEAELGPNATTSRIQKIQHAALFLQFHQVMRQHNDAILSKQEKCKQFIIRQLEVSGR-EVSEEEVDNMIEQGK-WEIFNENIIVDAKIT--RTQLSEIEQRHKELLNLESNMKDLRDLFLDVFMLVEEQGHQIQNIQANVEKTQDYVSVTKEKFKRAARYKKNNPLRRLCCCCCPWFR------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9D3G5-1", "uniprot_id": "STX11_MOUSE", "id": "Q9D3G5-1", "name": "Syntaxin-11", "aln": "-MKDRLAELQELSRSYDQQFPDGDNDFD----------APREDIVFETDNILESLYRVIQDIQDENQLLLIDVRRLGRQNVRFLTSMRRLSSIKRDTNSIAKAIKTRGEGIHQKLRSMKELSEQAEARHGAHSAVARISHAQYSALARAFQQAMYEYNQAEMKQRDNCKIRIQRQLEIMGK-DMSGEQIEDMFEQGK-WDVFSENLLADLKGA--RAALNEIESRHRELLRLEGRIRDVHELFLQMAVLVEKQEDTLNVIELNVQKTLDYTGEAKAQVRKAVQYKKKNPCRTICCFCCPCVN------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K516-1", "uniprot_id": "A0A0G2K516_RAT", "id": "A0A0G2K516-1", "name": "Syntaxin-11", "aln": "-MKDRLAELQELSRSYDQQFPDGDDDFD----------APQEDIVFETDHILESLYRVIQDIQDENQLLLIDVRRLGRQNVRFLTSMRRLSSIKRDTNSIAKAIKTRGEGIHQKLRSMKEMSEQAEAQHGAHSAVARISHAQYSALARAFQQAMYEYNQAEMKQRDNCKIRIQRQLEIMGK-DVSGEQIEDMFEQGK-WDVFSENLLADVKGA--RAALNEIESRHRELLRLEGRIRDVHELFLQMAVLVEKQADTLNVIELNVQKTLDYTGEAKAQVRKAVQYKKKNPCRTICCFCCPCVN------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P39926-1", "uniprot_id": "SSO2_YEAST", "id": "P39926-1", "name": "Protein SSO2", "aln": "-MSNANPYENNNPYAENYEMQEDLNNAP--------------TGHSDGSDDFVAFMNKINSINANLSRYENIINQIDAQHKDLLTQVSEEQ---------EMELRRSLDDYISQATDLQYQLKADIKDAQRDGLHDSNKQAQAENCRQKFLKLIQDYRIIDSNYKEESKEQAKRQYTIIQP-EATDEEVEAAINDVNGQQIFSQALLNANRRGEAKTALAEVQARHQELLKLEKTMAELTQLFNDMEELVIEQQENVDVIDKNVEDAQQDVEQGVGHTNKAVKSARKARKNKIRCLIICFIIFAIVVVVVVVPSVVETRK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . : :: :: : . : * * . : . ::. ** : . :::: :. : :* : : : ::. ** :: .** : :: ::* : * * . :: *: : : : . . * . ", "identical_positions": 14, "similar_positions": 53, "identity": "4.38%" }, { "cls_id": "homologset.agr.SGD:S000004797", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JYH9-1", "uniprot_id": "A0A0G2JYH9_RAT", "id": "A0A0G2JYH9-1", "name": "", "aln": "MAASVQAAAAPSGVLGTCGLEQILEALKLLLSPGGSGSTSLQNTKHDVLLETLKSNLSALEAKFLKDAQWKKLKTLRDEIADKAEWPQSSEDITWSFTSQTLLLLLCLKEIMTRLVAEFNPGKPNPRTPEAAPALSPDTLSVSQQKTFQSVLQFVVTLGVCPYLMPGVGVPLRDRTEFGAVVQGIVRLEAAPHATRRLYICCRVLLDLAQHASLGSLIFCRHFGDIAAGLCQLGFCPTKRKPPVPVEEVLTEEERTLSRQALRDILDQVYQPLAVRELLILQGGSPQSCTDVKTKLRC--PAPAWLRRLCGQLLSERLMRPNGVQAVVRGILEGAGAGAAGGSDAEATAADWKKCDLIAKILASCPQQSLSPESYYKDICPQILDLFHLQDKLTARQFQRVATTTFTTMLRERPELAPKYLLQPMLAPLHRCSTTAEIPESDMVPGTVLVTEEELSRCVEDVFKVYVVANEPLPVLLDSLLPLLGVFFSLYCFTQQSASHIRSLCQEILLWALVKLERKRAIASLRGFSGLDKAVPALHPQCQFRAATHGGIVITVKEALSD-DEDEALYQKVSSEQSQMEHLGDLLLHCQPCGLAGDFFIFCLKELSHLLEENEAEFTPKPPCSTSLLELEQHQTLLIEDQERKLLVLQLLAVLCEKMSEQIFTHITQVVDFVAATLQRACAGLAHEAESTVGSQTLSMAMGLVAAMLGGAVQKPFVGAALKSSDFVVLKQLLPLLEKVSNTYPDPVIQELAVDLRITISTHGAFSTEAVSTAAQSTLNKKDPEQKIKEQRQTSYDASTEGTQNRPEQEQ------------NPLRTGQGSSEPCTATSQPPGNITTEQFREVLLSACDPQVPTRAAALRTLSRWVEQREGRALEEQKKLLQIFLENLEHEDSFVYLSAIQGVALLSDVYPEEILVDLLARYDSSKDKHTPETRMKVGEVLMRIVRALGDMVS-KYREPLIHTFLRGVKDPDG-----AHRASSLSNLGELCQRLDFLLGPVVHEVTICLTAVAKTDTDVQVRRAAVHVVVLLLRGLS--QKATEMPVQLTTALRVVGTSLFALVVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQSLFAFLEHRRMRRAGRPLKLHCSQRRRSVALCIAAYQEDPEYLRKCLRSAQRIAFPNLKVVMVVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMERVRAVVWASTFSCIMQKWGGKREVMYTAFKALGNSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGGVGGDVQILNKYDSWISFLSSVRYWMAFNVERACQSYFGCVQCISGPLGMYRNSLLQQFLEDWYHQKFLGSKCSFGDDRHLTNRVLSLGYRTKYTARSKCLTETPTKYLRWLNQQTRWSKSYFREWLYNSLWFHKHHLWMTYESVVTGFFPFFLIATVIQLFYRGRIWNILLFLLTVQLVGIIKATYACFLRGNAEMIFMSLYSLLYMSSLLPAKIFAIATINKSGWGTSGRKTIVVNFIGLIPVSIWVAVLLGGLAYTAYCQDLFSETELAFLVSGAILYGCYWVALLMLYLAIIARRCGKKPEQYSLAFAEV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C3S2-1", "uniprot_id": "TNG6_MOUSE", "id": "Q8C3S2-1", "name": "Transport and Golgi organization protein 6 homolog", "aln": "MAASGPAAAAPSGVLVTCGLEQVLEALKLLLSPGGSGSSSLQNTKHDVLLQTLKSNLSALEAKFLKDAQWKKLKALRDELADKAEWPQSSEDITWSFTSQTLLLLLCLKEVLARLVADFNPGKPNPRTPEAAPALSPDTLSVSQQKTFQSVLQFVVTLGVCPYLIPGVGVPLRDRTEFGAVVQDVVRLEAAPHATRRLYICCRVLLDLAQHASLGSLIFCRHFGDIAAGLCQLGFCPTKRKPPGPVEEVLTEEERTLSRRALRDILDQVYQPLAVRELLTLQGGPRQPCTDVKTQLRCRAQAPAWLRRLCGQLLSERLMRPNGVQAVVRGILEGAGAGAAGGSDAEATAADWRKCDLIAKILASCPQQSLSPESYYKDICPQILDLFHLQDKLTARQFQRVATTTFITLSRERPELAAKYLLQPMLAPLQRCLSTAEIPESDMVPGAILVTEEELSRCVEDVFKVYVVANEPVPVLLDSLLPLLRVFFSLYCFTQQSVSHIRSLCQEILLWILVKLERKKAIASLKGFSGLDKTVPTLHPQCQFRAATHGGIVITAKEAISD-DEDEALYQKVSSEQSQVEHLGDLLLHCQQCGLAGDFFIFCLKELSHLLEDREAEFTPKPSCYASLLELEHHQTLLIEDQERKLQVLQLLAVLCEKMSEQIFTHVTQVVDFVAATLQRACAGLAHEAESAVGSQTLSMSMGLVAVMLGGAVQ-------LKSSDFAVLKQLLPLLERVSNTYPDPVIQELAADLRITISTHGAFSTDAVSTAAQSTLNQKDPGQKIEEQRQTSPDISTEGAQKPP-------------------RTGQGSSGPCTATSQPPGSITTQQFREVLLSACDPEVPTRAAALRTLARWVEQREARALEEQKKLLQIFLENLEHEDSFVYLSAIQGIALLSDVYPEEILVDLLAKYDSGKDKHTPETRMKVGEVLMRVVRALGDMVS-KYREPLIHTFLRGVRDPDA-----AHRASSLANLGELCQCLHFLLGPVVHEVTACLIAVAKTDNDVQVRRAAVHVVVLLLRGLS--QKATEV----------------------------------------------------LSDVLRDLYHLLKHVVRLEPDDVAKLHAQ----------LALEELDEIMRNFLFPPQKLEK---KIVVLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0B7-1", "uniprot_id": "TNG6_HUMAN", "id": "Q9C0B7-1", "name": "Transport and Golgi organization protein 6 homolog", "aln": "MAAR---QAVGSGAQETCGLDRILEALKLLLSPGGSGSSSLQVTKHDVLLATLKSNLSALEDKFLKDPQWKNLKLLRDEIADKAEWPQNSVDVTWSFTSQTLLLLLCLKETMIRLAANFNPGKPNPRTPEVAPALSPDALSISQQKTVQFVLQFVVTLGICPYLMPGVGVPLRYRTEFGAVVQDVVCFDAAPDATRRLYTSCKALLNVAQHTSLGSLIFCHHFGDIAAGLCQLGFCPTKRKLLTPAEEVLTEEERTLSRGALRDMLDQVYQPLAVRELLILQGGPPQSCTDVKTQMRCR--APAWLRRLCGQLLSERLMRPNGVQAVVRGILEGAGAGAAGGSDAEVTAADWKKCDLIAKILASCPQQSLSPENYYRDICPQVLDLFHFQDKLTARQFQRVATTTFITLSRERPHLAAKYLLQPVLAPLHRCLNTAELSESDMVPGTILVTEEELSRCIEDVFKVYVVGNEPLTVLMDSLLPVLGVLFLLYCFTKQSVSHIRSLCQEILLWILGKLERKKAIASLKGFAGLDKAVPSLHSLCQFRVATQGGIMITIKEAISDEDEDEALYQKVSSEQGRVEHLGDLLSHCQECGLAGDFFIFCLKELTHVASENETELKTEPFSSKSLLELEQHQTLLVEGQERKLLVLQLMAVLCERMSEQIFTNVTQVVDFVAATLQRACASLAHQAESTVESQTLSMSMGLVAVMLGGAVQ-------LKSSDFAVLKQLLPLLEKVSNTYPDPVIQELAVDLRITISTHGAFATEAVSMAAQSTLNRKDLEGKIEEQQQTSHERPTDVAHSHLEQQQSHETAPQTGLQSNAPIIPQGVNEPSTTTSQKSGSVTTEQLQEVLLSAYDPQIPTRAAALRTLSHWIEQREAKALEMQEKLLKIFLENLEHEDTFVYLSAIQGVALLSDVYPEKILPDLLAQYDSSKDKHTPETRMKVGEVLMRIVRALGDMVS-KYREPLIHTFLRGVRDPDG-----AHRASSLANLGELCQRLDFLLGSVVHEVTACLIAVAKTDGEVQVRRAAIHVVVLLLRGLS--QKATEV----------------------------------------------------LSAVLKDLYHLLKHVVCLEPDDVAKLHAQ----------LALEELDDIMKNFLFPPQKLEK---KIMVLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12751-1", "uniprot_id": "RTP1_YEAST", "id": "Q12751-1", "name": "RNA polymerase II assembly factor RTP1", "aln": "----------------------------------MNEDKEQKINIHDILNTRPKLTKKTALDVFFEDLDDNVITPINEYVLDSGSSSSSSIYQALKCSNNNEFVAVLLQKFQNLHIHVLEQQR---RLIESKSDLLP--ISLHDMKYVDELINLLIIHGIDANLSPTMKIPFDSK----RINTFKKGQKSAEYETPRWHTINNDTLSQVITVFYN-VLTSERSSDYLREIISKGSAYANILLGLIVLHLQLPNRYSSQMITNLEDTQETYTLFGVYTLLVETIQDEKVREPILSKLTT-----LTLRRPENGLISLIDFVLGVRDAEDIDIEKFNRIYQILMSKPKTMTNLQYLTELFKQIYDG---LTFVNRPILVTCLNGLILKFYLRNKRIVNDFLFKKVRSIIFNSP-----LTDHTAKELNDVINVLISLSKNSSSDLLN-DLVTSCPDEDGTTPGQFFLYVWIYALFLKKNQKLDPLEINKLSISDNKSTDSIHFPEQSSSKYYEVVLSLLKSLIVITEN-FQYLNVLSLNLLNFEHEKWKYLIDLDTQLPYISVKNTDMAELFFEKGSKNSQISEFLQDMDLSIELFMEFLVLLNDEEQSKTLFLDILKRWVHHTKKSEKRSSDNHSGMPSVTDNALILMDLKLLECMNNRFKTKIVNKPKDVLIVIDQLID-----VVQEKDETIQEVEADSDDEVEEGEETEELD---------PNENSSYKIILQLLSTVLSESSSSILLQNSYILKSISRKLQSFNTNASEIDALLASIDNILINGHTTERNDNIEIEMD----------------------------------------------EERLDKAITSLHDPLVPIKSYGLTELRHLAEKKS--PVISLEKVLQIHLDYLKNMDPFIYLNVIKGLTTLCELEPETILPLLAEFYANKKKKNRLDDVLKVGEVFINYIQRQNELFQGKLAYLIIDTCLSIVRPNDSKPLDNRWRMSSMSILGMCLQINARGVSDRIRDMLDCVFGILQLE-QPQNHLKDKDDSFLMRRSAV--HLIHDL-------------------------------------------------------LYSTGFDLLPFEYNYDKLKTLLSYVR-----------DQDEDYMVCEQIDKLLTVLDSL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VJ29-1", "uniprot_id": "TNG6_DROME", "id": "Q9VJ29-1", "name": "Transport and Golgi organization protein 6", "aln": "---------------------------------------MINTAKYFALLESLR---------------------FSKALANTANNSGTAEALEINLRILEKYAKLEIGQQLHELCLEYQLTDDHESSIDPDSDRTICYIIRLQHVLHSIMRNINFHSDAKEDLISVAHLKLCIQASQELSYYSLRCQLHEDFYKSPIFCEAQGKIKANFSLMLLSIQFFINLLHIRQYHIANSMELVQRDLLAAIVSLRVQQDSPLLDKAIAYLWQYESKADFFRNILLFKATTLCP----------------TLAQLLHRQLLGKLHLPQGFASLVEALHQNPNVNSS------------RNAEIVASIVARKGFSQLAQEKMVLQVLEYCKFYLQNADKMCAGVLSLRRLYDLS-----------DTNQKLIKEILFKHWETLCNPE-DIINGLILMDHQELCNRILLWQHLFCSSTVACLP-SNLLVPYLPLLLQLYDGLPMELPASSQISAIILRCLDNREMKNELPAILQKLFKWEIEK-------EPPWKCLNPRIIILPSMNTTQIQVKVAHKDHLADHDMGRILPGLLTSSSHHSLTCKVFLSLLGFIAKQINDKSSASVDFISSEAELKDFLHSKYQLKLD----LLIALNQMVAHQPLRAQLSQHTKELLHILKDLLVHR----SREQD----------------------------------TTDQILLLVLNLLQEILEGSENIQLSEACKELKEQLHLLGTRSSNPLIQQSVKSLLTIIHGAWRPSE-----------------------------------------------------AVKIQPFQRARSLIEEKQSHMQVYGIQMMIDLLKKRDPATLAQGQLIIALALTTLKDKESYTFLNCVRLFVSLVHVMESDVLDKLSDEYLS--ETAHLDYRLVVGEAILKVAQELGPLCF-RYKAVLLNCFMYGSRSPVH-----EFRMSAFANLAQLCRLLAFQVQNFFHELLQLVNSELTTGGYVPSKRAAVLVLAELLNGMENLLDYQ--------------------------------------------------------EMLLPIYRLLKAIEADESCDPQMRQHAAN---------GLKILNKKCTKLIQSALEEKSLQKQIKVLGIKDDDSPQRRNRHILELN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * : : . : :... . .: . : : : : : . : : . : :: . . * . : : : . . . :. : . . . .: : : . : : . :* * : : : : : ::. .* : . : :* . : : . : : : .. *:: :: : :: : * * : : . . . :. . : : . : . . :.:. : : . : .:: : . . : . * : : :: : .::: .: : :: : . :* **. : . . : : . *: : ::. : : : : : .. : : .: : :::. .: : :: : * *:. :.: :*. :: .. * .: . :* * * . .. : : ***.::. : . : : ::. : : * *::: *. : : .::: : . : : .. : : :* . : ", "identical_positions": 28, "similar_positions": 215, "identity": "1.74%" }, { "cls_id": "homologset.agr.SGD:S000004798", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07901-1", "uniprot_id": "HS90A_MOUSE", "id": "P07901-1", "name": "Heat shock protein HSP 90-alpha", "aln": "MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPSKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEEKEEEKEKEEKESDDKPEIEDVGSDEEEEEKKDGDKKKKKKIKEKYIDQEELN--------------------KTKPIWTRNPDDITN--------------------------------EEYGEFYKS-------------------------------------------------------------------------------------------------------------------LTNDWEEHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTE------------------------------------------------------------------------LAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLK------------------------------------------------------------------------DYCTRMKENQKHIYFITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEAD-KNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDD--PTVDDTSAAVTEEMPP-------------LEGDDDTSRMEEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZQP6-1", "uniprot_id": "A0A8I5ZQP6_RAT", "id": "A0A8I5ZQP6-1", "name": "", "aln": "----------------------------------------------------------------------------------WTRGRSCTLISFPTSKTEPSLLRN---------------------------------------------------------------------------------------------------------------------------VSDDEAEEKEEKEEEKEKEEKESDDKPEIEDVGSDEEEEEKKDGDKKEKKKIKEKYIDQEELN--------------------KTKPIWTRNPDDITN--------------------------------EEYGEFYKS-------------------------------------------------------------------------------------------------------------------LTNDWKEHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVQRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISHEMLQQSKILKVIRKNLVKKCLELFTE------------------------------------------------------------------------LAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSAFGDEMVSLK------------------------------------------------------------------------DYCTRMKENQKHIYFITGETKDQV-----------HGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSSCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEAD-KNDKSVKDLVILLYKTALLSSSFSLEDPQTHANRIYRMIKLGLGIDEDD--PTVDDTSAAVTEEMPP-------------LEGDDDISRMEEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P82995-1", "uniprot_id": "HS90A_RAT", "id": "P82995-1", "name": "Heat shock protein HSP 90-alpha", "aln": "MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEEKEEEKEKEEKESDDKPEIEDVGSDEEEEEKKDGDKKKKKKIKEKYIDQEELN--------------------KTKPIWTRNPDDITN--------------------------------EEYGEFYKS-------------------------------------------------------------------------------------------------------------------LTNDWEEHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTE------------------------------------------------------------------------LAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLK------------------------------------------------------------------------DYCTRMKENQKHIYFITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEAD-KNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDD--PTVDDTSAAVTEEMPP-------------LEGDDDTSRMEEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15108-1", "uniprot_id": "HSC82_YEAST", "id": "P15108-1", "name": "ATP-dependent molecular chaperone HSC82", "aln": "-------------------------------------------------------------------------MAGETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASD------------------------------------------------------------------------------------------------------------ALDKIRYQALSDPKQLETEPDLFIRITPKPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKNNEDEQYIWESNAGGSFTVTLDEVNERIGRGTVLRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLLVTKEVEKEVP---IPEEEKKDEEKKDEDDK---KPKLEEVDEEEEEKKP-----KTKKVKEEVQELEELNKTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNE------------------------------------------------------------------------IAEDSEQFDKFYSAFAKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLT------------------------------------------------------------------------DYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITKD-FELEETDEEKAEREKEIKEYEPLTKALKDILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTNLLFETALLTSGFSLEEPTSFASRINRLISLGLNIDEDE--ETETAPEAST-EAP---------------VEEVPADTEMEEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P02828-1", "uniprot_id": "HSP83_DROME", "id": "P02828-1", "name": "Heat shock protein 83", "aln": "-----------------------------------------------------------------------MPEEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASD------------------------------------------------------------------------------------------------------------ALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADKVTVTSKNNDDEQYVWESSAGGSFTVRADNS-EPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKLLVEKEREKEVSDDEADDEKKEGDEKKEMETD---EPKIEDVGEDEDADKKDKDAKKKKTIKEKYTEDEELNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRTPFDLFENQKKRNNIKLYVRRVFIMDNCEDLIPEYLNFMKGVVDSEDLPLNISREMLQQNKVLKVIRKNLVKKTMELIEE------------------------------------------------------------------------LTEDKENYKKFYDQFSKNLKLGVHEDSNNRAKLADFLRFHTSASGDDFCSLA------------------------------------------------------------------------DYVSRMKDNQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVIQHLKEYKGKQLVSVTKEGLELPEDESEKKKREEDKAKFESLCKLMKSILDNKVEKVVVSNRLVDSPCCIVTSQFGWSANMERIMKAQALRDTATMGYMAGKKQLEINPDHPIVETLRQKADAD-KNDKAVKDLVILLFETSLLSSGFSLDSPQVHASRIYRMIKLGLGIDEDE--PMTTDDAQSAGDAPSL-------------VEDTEDASHMEEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q90474-1", "uniprot_id": "H90A1_DANRE", "id": "Q90474-1", "name": "Heat shock protein HSP 90-alpha 1", "aln": "--------------------------------------------------------------MPEKSAQPVMEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSD------------------------------------------------------------------------------------------------------------ALDKIRYESLTDPSKLDSCKDLKIELIPDQKERTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPDFG-ESIGRGTKVILHLKEDQSEYVEEKRIKEVVKKHSQFIGYPITLYIEKQREKEVDL-EEGEKQEEEEVAAGEDKD---KPKIEDLGADEDEDSKDGKNKRKKKVKEKYIDAQELNKTKPIWTRNPDDITNEEYGEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCEELIPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLDLFTE------------------------------------------------------------------------LAEDKDNYKKYYEQFSKNIKLGIHEDSQNRKKLSDLLRYYTSASGDEMVSLK------------------------------------------------------------------------DYVSRMKDTQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEYDGKNLVSVTKEGLELPEDEEEKKKQDELKAKYENLCKIMKDILDKKIEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKSQALRDNSTMGYMTAKKHLEINPAHPIVETLREKAEAD-KNDKAVKDLVILLFETALLSSGFTLDDPQTHANRIYRMIKLGLGIDDDD--SVVEEISQPAEEDMPV-------------LEGDDDTSRMEEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q58FG1-1", "uniprot_id": "HS904_HUMAN", "id": "Q58FG1-1", "name": "Putative heat shock protein HSP 90-alpha A4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MESLTDPSKLDSGKEPHISLIPNKQDRTLTIVDTGIGMTKADLINNLGTITKSETKVFMEVLQAGADISMIGQFSVGFYSAYSVAEKVTVITKHNNDEQYAWESSLRGSFT-----------------------------------------------------------------------------------------------------------------------------------------EYREFYKSLTINWEDYLAVKHFSVEGQLEFRAFLFVPRLAPFELLETRKKKNKIKLSARRDLIMDNCEELIPEYLNFIRGVVDSEDLPLNIFR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ETKDQVANSTIVQRLWKHGLEVIYTIEPIDEYCVQQLKEFEGKTLVSVTKEDLELPEDEEEKKKQEEGKQKTK----------QKKNQSLRTS----------AKSTYGWTANMERIMKAQALRDNSTTGYMAAKKHLEINPDHSFIDTLRQKAETD-KNDKSVKDLVILLYETALLSSDFGLEGPQTHANRIYRMNKLGLGTDEDD--PTADDTSAAVTEEMPP-------------LEGDDDTSRMEK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GLF3-1", "uniprot_id": "A0A8I6GLF3_RAT", "id": "A0A8I6GLF3-1", "name": "", "aln": "----------------------------------------------------------------MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASD------------------------------------------------------------------------------------------------------------ALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKS-------------------------------------------------------------------------------EDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEE---KPKIEDVGSDEEDES----------------------------------------------SKDKKKKTKTIKEKSID-QEEL----------------NKTKP---------IWTRNPDDITQEEYGEFYKSLTNAWEDHLA----------------------------------------------------------------------------------------------------------------------------------------------------MTSLS------------------------------------------------------------------------GYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEAD-TNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDE--VTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P34058-1", "uniprot_id": "HS90B_RAT", "id": "P34058-1", "name": "Heat shock protein HSP 90-beta", "aln": "----------------------------------------------------------------MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASD------------------------------------------------------------------------------------------------------------ALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHG-EPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKEDEE---KPKIEDVGSDEEDDS----------------------------------------------GKDKKKKTKKIKEKYID-QEEL----------------NKTKP---------IWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLS------------------------------------------------------------------------EYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEAD-KNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDE--VTAEEPSAAVPDEIPP-------------LEGDEDASRMEEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08238-1", "uniprot_id": "HS90B_HUMAN", "id": "P08238-1", "name": "Heat shock protein HSP 90-beta", "aln": "----------------------------------------------------------------MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASD------------------------------------------------------------------------------------------------------------ALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHG-EPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEE---KPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLN------------------------------------------------------------------------------------------------------------------------------------------------ISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEAD-KNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDE--VAAEEPNAAVPDEIPP-------------LEGDEDASRMEEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58FF7-1", "uniprot_id": "H90B3_HUMAN", "id": "Q58FF7-1", "name": "Putative heat shock protein HSP 90-beta-3", "aln": "----------------------------------------------------------------MPEEVHHGEEEVETFAFQAEIAQLISLIINTFYSNEEIFLQELISNASD------------------------------------------------------------------------------------------------------------ALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLALVDTGIGMTKADLINNLRTIAKSGTKACMEALQA---------------------EKLVVITKHNDDEQYAWESSAGGSFTVHADHG-EPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEQDKEISDDEAEEEKGEKEEEDKDDEE---KPKIKDVGSDEEDDS-------------------------------------KEYGEFYKSLTSDWEDHLAVKHFSVEGQLEFRALLFSPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIHGVVDSEDLPLN------------------------------------------------------------------------------------------------------------------------------------------------ISREMLQQSKILK---------------------------------------------------------------------YVSHMKETQKSTYYITGESKEQVANSAFVERVRKQGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKEKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMEQIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKAEAD-KNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNHIYHMIKLGLGTDEDE--VAAEEPSDAVPDEIPP-------------LEGDEDASRMEEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11499-1", "uniprot_id": "HS90B_MOUSE", "id": "P11499-1", "name": "Heat shock protein HSP 90-beta", "aln": "----------------------------------------------------------------MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASD------------------------------------------------------------------------------------------------------------ALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHG-EPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKEDEE---KPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLN------------------------------------------------------------------------------------------------------------------------------------------------ISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEAD-KNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDE--VTAEEPSAAVPDEIPP-------------LEGDEDASRMEEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q58FF6-1", "uniprot_id": "H90B4_HUMAN", "id": "Q58FF6-1", "name": "Putative heat shock protein HSP 90-beta 4", "aln": "----------------------------------------------------------------------------------------MSLIINTFYSNKEIFLQELISNASD------------------------------------------------------------------------------------------------------------ALDKIRYESLTDPSKLDGGKELKIDIIPNPRECILTLVNTGIGMTKADLINNLGAIAKSGTEAFMEAFQSCAEISMIGQFGVG-FYSAYLVAEKVAITKHNDEEQYSWVSSAGSSFTLHVDHG-EPIDRDTKVILHLKEDQTEYLEERWVKEVVKKHPQFIGCLIAVYLEKEPEKEISDD--EEEKGEKEEEDKDDKE---KPKTEDVGSDEEDDT----------------------------------------------DKNNKKKTKKIKEKYTD-REEL----------------NQTKP---------IWTRNPDDITQEECGEFYKSLTSAWEDHLAVKQFPVEEQEENEQLCVHHVWIMDSFDDLMPEYVG-----------------------------------------------------------------FVREDKENNKKLDEVFSKISWLGIHEDSINWRHLSELLWSHTFQSGDEMTSLS------------------------------------------------------------------------EYVSCMKEAQKSICDIIGECKEQVANSAFVEQEWKKGFEVIYMSEPIDEYCVQQLKEFDGKSLLSVTKEGLELPEDEEEKKIMEESNVKFENLCRLMKEILDKKVERVTISSRLVSSPCRIVTSTYS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O57521-1", "uniprot_id": "HS90B_DANRE", "id": "O57521-1", "name": "Heat shock protein HSP 90-beta", "aln": "----------------------------------------------------------------MPEEMRQ-EEEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELVSNASD------------------------------------------------------------------------------------------------------------ALDKIRYESLTDPTKLDSGKDLKIDIIPNVQERTLTLIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVKVDHG-EPIGRGTKVILHLKEDQTEYIEEKRVKEVVKKHSQFIGYPITLYVEKERDKEISDDEAEEEKAEKEEKEEEGED---KPKIEDVGSDDEEDT----------------------------------------------KDKDKKKKKKIKEKYID-QEEL----------------NKTKP---------IWTRNPDDISNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFAELAEDKDNYKKFYDAFSKNLKLGIHEDSQNRKKLSELLRYQSSQSGDEMTSLT------------------------------------------------------------------------EYVSRMKENQKSIYYITGESKDQVAHSAFVERVCKRGFEVLYMTEPIDEYCVQQLKDFDGKSLVSVTKEGLELPEDEDEKKKMEEDKAKFENLCKLMKEILDKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKAEAD-KNDKAVKDLVILLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDEDEDVPVEEPSSAAAPEDIPP-------------LEGDDDASRMEEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07900-1", "uniprot_id": "HS90A_HUMAN", "id": "P07900-1", "name": "Heat shock protein HSP 90-alpha", "aln": "-----------------------------------------------------------MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSD------------------------------------------------------------------------------------------------------------ALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTG-EPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEK----------------------------------------------KDGDKKKKKKIKEKYID-QEEL----------------NKTKP---------IWTRNPDDITNEEYGEFYKSLTNDWEDHLA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q14568-1", "uniprot_id": "HS902_HUMAN", "id": "Q14568-1", "name": "Heat shock protein HSP 90-alpha A2", "aln": "-----------------------------------------------------------MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSD------------------------------------------------------------------------------------------------------------ALDKIWYESLTDPSKLDSGKELHINLIPNKQDQTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVSFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTG-ERMGRGTKVILHLKEDQTEYLEEQRIKEIVKKHSQLIGYPITLFVEKECDKEVSDDETEEKEDKEEEKEKEEKESKDKPEIEDVGSDEEEEK----------------------------------------------KDGDKKKKK-TKEKYID-QEEL----------------NKTKP---------IWTRNPDDITNEEYGEFCKNLTNDWEDHLA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKHFSVEGQLEFRALLFVP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58FG0-1", "uniprot_id": "HS905_HUMAN", "id": "Q58FG0-1", "name": "Putative heat shock protein HSP 90-alpha A5", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGFHHVGQAGLELLTSGHPALER---------------------------------------------------------------------------------RPEYLEERRIKEIVKKHSQFIGYPITLFVEKKRNKQVSDAEAEKKEDKRKKKKESNDK----PEIEDVGSDEEEEK-----------------------------------------------KDADKKKKKSKEKYID--QEL----------------NKTKP---------IWTRNPDAITNEEYGEFHQSLTNNWEDHLAVKHFSVEG-------------------------------------------------------------------------------------------------------------------------------------------QLEELK------------------------------------------------------------------------DSRRVMKANQKHIYYITGETKDQVANSAFVECLQKHGLEVIYMIELIDKYCVQQLKELESKTVVSVAKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDMLEKKVKKVVVSN---------------------------------------------------------------------------------------CMEDPQRHTNKIYRMIKLGLGVDEYD--PTANDINAAITKEMPP-------------LRGGDDTSRMEEVGGSG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . : :. *. : *: .:.* : * .* :.:.. : * :..: . : . .: ", "identical_positions": 6, "similar_positions": 30, "identity": "0.48%" }, { "cls_id": "homologset.agr.SGD:S000004800", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y2R5-1", "uniprot_id": "RT17_HUMAN", "id": "Q9Y2R5-1", "name": "Small ribosomal subunit protein uS17m", "aln": "MSVVRSSVHARWIVGKVIG-TKMQKTAKVRVTRLVLDPYLLKYFNKRKTYFAHDALQQCTVGDIVLLRALPVPRAKHVKHELAEIVFKVG---------KVIDPVTGKPCAGTTYLES-----------------------PLSSETT------------------QLSKNLEELNISSAQ----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03246-1", "uniprot_id": "RT17_YEAST", "id": "Q03246-1", "name": "Small ribosomal subunit protein uS17m", "aln": "-------MARQNFLGLVVSQGKMQKTVKVRVETKVFNKKINKELFHRRDYLVHDEGEISREGDLVRIEAT-RPLSKRKFFAIAEIIRNKGQQFALYESEAQLSVAKEEAQKAKEFLDKRSVRENKLNEKTTLLRDIRTIQDALSSGSTPKELLEIKQRYGIQDFSQETVRQLLQLDISGLEVNLEKQRSLIDRIQTRLSELLSNDLKCDQFLKDHGVEDPLTLKKNIKKNLLRKHVMMDMQQPSQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ::* *:. *****.**** *:: : * : :*: *:.** : . **:* :.* * :*: . :***: : * :. .. :. .. :*:. .*** :* : ::* :*:**. : ", "identical_positions": 36, "similar_positions": 46, "identity": "14.69%" }, { "cls_id": "homologset.agr.SGD:S000004801", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AWV3-1", "uniprot_id": "A0A8I6AWV3_RAT", "id": "A0A8I6AWV3-1", "name": "Glycine cleavage system P protein", "aln": "MQLCARAWGLRLGPGAGGGHRLARGTGLSWAPRSRDSSSGGGGGGG-DRGAAGASRLLERLLPRHDDFARRHIGPGDKDRREMLQALGLASIDELIEKTVPASIRLKRPLKLEDP---VCENEILETLHAIASKNQ-IWRSYIGMGYYNCSVPQTILRNLLENSGWVTQYTPYQPEVSQGRLESLLNYQTMVSDITGLDMANASLLDEATAAAEAMQLCHRHNKRK--RFFIDPRCHPQTIAVVQTRAKYRGVIVELKLPHEMD-----FSGKDVSGVLFQYPDTEG---KVEDFTELVERAHQTGSLTCCATDLLALCILRPPGEFGVDIALGNSQRFGVPLGYGGPHAAFFAVRESLVRMMPGRMVGVTRDATGKEVYRLALQTREQHIRRDKATSNICTAQALLANMAAMFAIYHGSHGLQHIAKRVHNATLILSEGLKR--AGHQLQHDLFFDTLKVQCG--CSLKEVLGRAAQRQ-INFRLFDDGTLGISLDETVTEKDLDDLLWIFGCESSTELVAEGMGEEWRGLLGSSFKRTSPFLTHQVFNSYHSETNLVRYMKKLENKDISLVHSMIPL------------VAPITWREFANIHPFVPLDQAQGYQQLFQELEKDLCELTGYDRVSFQPNSGAQGEYAGLATIRAYLDQKGERHRTVCLIPKSAHGTNPASAYMAGMKIQPVEVDRYGNIDVAHLKAMVDKHKENLAAIMITYPSTNGVFEENISDVCALIHQHGGQVYLDGANMNAQVGICRPGDFGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLVPFLPSHPIVCLKPNED-TWPVGTVSAAPWGSSSILPISWAYIKMMGGKGLKEATEIAILNANYMAKRLERYYRVLFRGARG---YVAHEFILDTRPFKKSANIEAVDVAKRLQDYGFHAPTMSWPVAGTLMIEPTESEDKAELDRFCDAMISIRQEIADIEEGRIDPRVNPLKMSPHSLT-CVTSSRWD-RPYSREVAAFPLPFVKPENKFWPTIARIDDIYGDQHLVCTCPPMEVYESPFSEQKRASS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91W43-1", "uniprot_id": "GCSP_MOUSE", "id": "Q91W43-1", "name": "Glycine dehydrogenase (decarboxylating), mitochondrial", "aln": "MQLCARAWGLRLGRGAGGGHRLARGTGLSWAQRSRDSSGGGGGGGGGDRGAAGASRLLERLLPRHDDFSRRHIGPGDKDRREMLQALGLASIDELIEKTVPASIRLKRPLKMEDP---ICENEILETLHAIASKNQ-IWRSYIGMGYYNCSVPQTILRNLLENSGWVTQYTPYQPEVSQGRLESLLNYQTMVSDITGLDMANASLLDEATAAAEAMQLCHRHNKRK--KFFVDPRCHPQTIAVVQTRAKYRGVLVELKLPHEMD-----FSGKDVCGVLFQYPDTEG---KVEDFTELVDRAHQTGSLTCCATDLLALCILRPPGEFGVDIALGNSQRFGVPLGYGGPHAAFFAVKENLVRMMPGRMVGVTRDATGKEVYRLALQTREQHIRRDKATSNICTAQALLANMAAMFAIYHGSQGLKHIAKRVHNATLILSEGLKR--AGHQLQHDLFFDTLKVQCG--CSVKEVLGRAAQRQ-INFRLFDDGTLGISLDETVTEKDLDDLLWIFGCESSAELVAEGMGEERRGLLGSSFKRTSPFLTHQVFNSYHSETNLVRYMKKLENKDISLVHSMIPLGSCTMKLNSSSELAPITWREFANIHPFVPLDQAQGYQQLFQGLEKDLCEITGYDRVSFQPNSGAQGEYAGLATIRAYLDQKGERHRTVCLIPKSAHGTNPASAHMAGMKIQPVEVDRYGNIDVAHLKAMVDQHKENLAAIMITYPSTNGVFEENIGDVCALIHQHGGQVYLDGANMNAQVGICRPGDFGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLSPFLPSHPVISIKPTEG-TWPVGTVSAAPWGSSSILPISWAYIKMMGGKGLKEATEIAILNANYMAKRLEKHYRVLFRGARG---YVAHEFILDTRPFKKSANVEAVDVAKRLQDYGFHAPTMSWPVAGTLMIEPTESEDKAELDRFCDAMISIRQEIADIEEGRIDPRVNPLKMSPHSLT-CVTSSCWD-RPYSREVAAFPLPFVKPENKFWPTIARIDDIYGDQHLVCTCPPMEVYESPFSEQKRASS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23378-1", "uniprot_id": "GCSP_HUMAN", "id": "P23378-1", "name": "Glycine dehydrogenase (decarboxylating), mitochondrial", "aln": "MQSCARAWGLRLGRGVGGGRRLAGGSGPCWAPRSRDSSSGGG-----DSAAAGASRLLERLLPRHDDFARRHIGPGDKDQREMLQTLGLASIDELIEKTVPANIRLKRPLKMEDP---VCENEILATLHAISSKNQ-IWRSYIGMGYYNCSVPQTILRNLLENSGWITQYTPYQPEVSQGRLESLLNYQTMVCDITGLDMANASLLDEGTAAAEALQLCYRHNKRR--KFLVDPRCHPQTIAVVQTRAKYTGVLTELKLPCEMD-----FSGKDVSGVLFQYPDTEG---KVEDFTELVERAHQSGSLACCATDLLALCILRPPGEFGVDIALGSSQRFGVPLGYGGPHAAFFAVRESLVRMMPGRMVGVTRDATGKEVYRLALQTREQHIRRDKATSNICTAQALLANMAAMFAIYHGSHGLEHIARRVHNATLILSEGLKR--AGHQLQHDLFFDTLKIQCG--CSVKEVLGRAAQRQ-INFRLFEDGTLGISLDETVNEKDLDDLLWIFGCESSAELVAESMGEECRGIPGSVFKRTSPFLTHQVFNSYHSETNIVRYMKKLENKDISLVHSMIPLGSCTMKLNSSSELAPITWKEFANIHPFVPLDQAQGYQQLFRELEKDLCELTGYDQVCFQPNSGAQGEYAGLATIRAYLNQKGEGHRTVCLIPKSAHGTNPASAHMAGMKIQPVEVDKYGNIDAVHLKAMVDKHKENLAAIMITYPSTNGVFEENISDVCDLIHQHGGQVYLDGANMNAQVGICRPGDFGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLAPFLPNHPVISLKRNED-ACPVGTVSAAPWGSSSILPISWAYIKMMGGKGLKQATETAILNANYMAKRLETHYRILFRGARG---YVGHEFILDTRPFKKSANIEAVDVAKRLQDYGFHAPTMSWPVAGTLMVEPTESEDKAELDRFCDAMISIRQEIADIEEGRIDPRVNPLKMSPHSLT-CVTSSHWD-RPYSREVAAFPLPFVKPENKFWPTIARIDDIYGDQHLVCTCPPMEVYESPFSEQKRASS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VH09-1", "uniprot_id": "Q9VH09_DROME", "id": "Q9VH09-1", "name": "Glycine cleavage system P protein", "aln": "------------------MQRFLGRSSQSLLLRCG-------------HRYLATTPVEEVIFPTKSDFPSRHIGPRKTDVVAMLDTLGFKSLAELTEKAVPQSIQLKRELDLDKP---LNEHELIRRIRDISLKNQ-LWRSYIGMGYHNCHVPHTIIRNMFENPGWTTQYTPYQPEIAQGRLESLLNYQTLVTDLTGLDVANASLLDEGTAAAEAMCLATRHNKRK--KLYLSNRVHPQTLSVVKTRTEALELEIVVGPIEQAD-----LPSRELAGILLQYPDTYG---DVKDFEDIAALAKKNGTLVVVATDLLSLTLLRPPAEFGADIAVGTSQRLGVPLGYGGPHAGFFACKQSLVRLMPGRMIGVTRDMDGNDAYRLALQTREQHIRRDKATSNICTAQALLANMSAMYAIYHGPEGLKAMANRIHHFTLTLQTGVLG--AGHEVINKNFFDTLHIRLGGGQSLEDLKERAEHKR-INLRYLEDDTVGVALDETVSVADVDDLLWVFKAEASVEHILARKDVLKNSIENSKFLRTSPYLQHPIFQSYHSESRMVRYMKKLENKDISLVHSMIPLGSCTMKLNSTTEMMPCSFRHFTDIHPFAPVEQAQGFHQMFKELEHDLCEITGYDRISFQPNSGAQGEYAGLRAIRSYHEHRNEGHRNICLIPISAHGTNPASAQMAGMKVEPIRILSNGSIDMAHLRAKAEEHAHELSCLMITYPSTMGVFEETVADICTLIHKHGGQVYLDGANMNAQVGLCRPGDYGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPYLPGHPVVSPLSSE--EHSFGVVSAAPFGSSAILPISWSYIKLMGSRGLKRATQVAILNANYMSKRLEQHYKTLYKAPNSQ--LVAHEFILDIRDLKKSANIEAVDVAKRLMDYGFHAPTMSWPVAGTLMIEPTESEDKEELDRFCDAMISIREEIAEIEAGRMDKAVNPLKMSPHTQA-QVISDKWD-RPYTREQAAFPAIFVKPDAKIWPTVGRIDDAYGDKHLVCTCPPILPDL-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P49095-1", "uniprot_id": "GCSP_YEAST", "id": "P49095-1", "name": "Glycine dehydrogenase (decarboxylating), mitochondrial", "aln": "-MLRTRVTALLCRATVRSSTNYVSLARTRSFHSQSILLKTAATDITSTQYSRIFNPDLKNIDRPLDTFARRHLGPSPSDVKKMLKTMGYSDLNAFIEELVPPNILKRRPLKLEAPSKGFCEQEMLQHLEKIANKNHYKVKNFIGKGYYGTILPPVIQRNLLESPEWYTSYTPYQPEISQGRLEALLNFQTVVSDLTGLPVANASLLDEGTAAGEAMLLSFNISRKKKLKYVIDKKLHQQTKSVLHTRAKPFNIEIIEVDCSDIKKAVDVLKNPDVSGCLVQYPATDGSILPPDSMKQLSDALHSHKSLLSVASDLMALTLLKPPAHYGADIVLGSSQRFGVPMGYGGPHAAFFAVIDKLNRKIPGRIVGISKDRLGKTALRLALQTREQHIKRDKATSNICTAQALLANVASSYCVYHGPKGLQNISRRIFSLTSILANAIENDSCPHELINKTWFDTLTIKLGNGISSEQLLDKALKEFNINLFAVDTTTISLALDETTTKADVENLLKVFDIENSSQFLSEDYS---NSFP-REFQRTDEILRNEVFHMHHSETAMLRYLHRLQSRDLSLANSMIPLGSCTMKLNSTVEMMPITWPQFSNIHPFQPSNQVQGYKELITSLEKDLCSITGFDGISLQPNSGAQGEYTGLRVIRSYLESKGENHRNVCLIPVSAHGTNPASAAMAGLKVVPVNCLQDGSLDLVDLKNKAEQHSKELAAVMITYPSTYGLFEPGIQHAIDIVHSFGGQVYLDGANMNAQVGLTSPGDLGADVCHLNLHKTFSIPHGGGGPAGAPICVKSHLIPHLPKHDVVDMITGIGGSKSIDSVSSAPYGNALVLPISYAYIKMMGNEGLPFSSVIAMLNSNYMMTRLKDHYKILFVNEMSTLKHCAHEFIVDLREYKAKG-VEAIDVAKRLQDYGFHAPTLAFPVPGTLMIEPTESENLEELDRFCDAMISIKEEINALVAG--QPKGQILKNAPHSLEDLITSSNWDTRGYTREEAAYPLPFLR-YNKFWPTVARLDDTYGDMNLICTCPSVEEIANETE-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : : . *. **:** .* **.::* .: : *: ** .* :* *.:: * . *:*:: :. *: **: :.:** **:. :* .* **::*.. * *.*******::*****:***:**:* *:*** :********.***.**: *. . .::: : :. : * ** :*::**:: : : . : . ::.* *.*** * * ..: :: :. :* *:**::* :*:**..:*.**.:*.***:***:*******.*** :.* * :***::*:::* *: . ***********:*****************::: :.:***..**: ::.*:. * * .: . *:: :. :**** :: * * ::: :* :. **: .: *:.::****.. *:::** :* * * : : . ..: * **. * : :*: :***: ::**:::*:.:*:**.:***** : * :: .*::**** * :*.**::::: **:***.:**:* :.:**********:** .**:* : :.* **.:**** ********** ***:*: *:. *.:* ..*: .::* .:*:.:******* *:** : . ::*..****************: *** *:**.********.********. .** ** ** *.** * :: ... **:**:*.: :****::***:**..** :: *:**:*** .**: :*: *: . .****:* * * .. :**:****** ********:::**.****:******: ************::** : * : : ** :**: : *. ** * *:** **:* *:: *:***:.*:** *** :*:****.: ", "identical_positions": 418, "similar_positions": 292, "identity": "39.81%" }, { "cls_id": "homologset.agr.SGD:S000004802", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88700-1", "uniprot_id": "BLM_MOUSE", "id": "O88700-1", "name": "RecQ-like DNA helicase BLM", "aln": "-----------MAAVPLNNLQEQLQRHSARKLNNQPSLSKPKSLGFTFKKKT-SEGDVSVTSVSVVKTPALSDKDVNVSEA--FSFTESPLHKPKQQAKIEGFFKHFPGRQQSKG-TCSEPSLPATVQTAQDTLCTTPKTPTAKKLP--VAVFKKLEFSSSADSLS---DWADMDDFDMSAS-DAFASLAKNP-ATRVSTAQKMKKTKRNFFKPPPRKANAVKTDLTPPSPECLQVDLTKESEEEEEEEEEAEGADCLSRDVICIDNDSASEELTEKDTQESQSLKAHLGAERGDSEKKSHEDEAVFHSVQNTEYFEHNDNDYDIDFVPPSPEEIISTASSSLKCSSMLKDLDDSDKEKGILSTSEELLSKPEEMTTHKSDAGTSKDCDAQQIR-IQQQLIHVMEHICKLVDTVPTDELEALN--CGTELLQQRNIRRKLLAEAGFNGN----DVRLLGSLWR----HRPDSLDNTVQGDSCPVGHPNKELNSPYLLSHSPSTEE--------CLPT---TTPGKTGFSATPKNLFERPLLNSHLQKSFVS-SNWAETPRMEN----------RNESTDFPGSVLTSTTVKAQSKQAASGWNVERHGQASYD---------------------------IDNFNIDDFDDDDDDDDWENIMHNFPASKSSTATYPPIKEGGPVKSLSERISSAKAKFLPVVSTAQNTNLSESIQNCSDK-LAQNLSSKNPKHEHFQSLNFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPG----VTIVISPLRSLIVDQVQKLTSFDIPATYLTGDKTDSEAANIYLQLSKKDPIIKLLYVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQREGLAALAYHAGLSDSARDEVQHKWINQDNCQVICATIAFGMGIDKPDVRFVIHASLPKSMEGYYQESGRAGRDGEISHCVLFYTYHDVTRLKRLIMMEKDGNYHTKETHVNNLYSMVHYCENITECRRIQLLAYFGEKGFNPDFCKKYPDVSCDNCCKTK--DYKTKDVTDDVKNIIRFVQEHSSSPGTR---NIGPAGRFTLNMLVDIFLGSKSAKVKSG------IFGKGTTYSRHNAERLFKKLILDKILDEDLYINANDQPIAYVMLGTKAHSVLSGHLKVDFMETENSSSIKKQK--------ALVAK-VSQREEVVKKCLGELTEVCKLLGKVFGVHYFN-IFNTATLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVIPVLQKYSEWTVPAEDGSPGA-----RGAPEDTEEE-EEEAP---------VSSHYFANQTRNERKRKKMSATHKPKRRRTSYGG-FRAKGGSTTCRKTTSKSKFYG--VTGSRSASCASQATS--SASRKLGIMAPPKP--VNRTFLRPSYAFS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZQW1-1", "uniprot_id": "D3ZQW1_RAT", "id": "D3ZQW1-1", "name": "RecQ-like DNA helicase BLM", "aln": "--MFGSPVGWIMAAVPLNNLQEQLQRHSARKLKNQFSISKPKPSGFTFKKKT-PEG-----DVSVVRTPVLSDKDVNMSEA--LSYTEPPLHKPKQQSNIDGFFKNSPGGQQSKE-TCSELSLPEVVQIPQDASCTTPKTPAVKKPH--VAIFKKLEFSSSADSLS---DWADIDDFDVPAS-DAFVSLTRNP-TTRVSTAKKLSSSKRNFFKPPPR-ASAVKADLTPSSPECLQVDLTKEQEEE---------ADCLSRDVICIDTDPASEELLEKDVQEGLSLDARLGTERVDSAKKSHEDKAAFQSPQNALYFEHNDNDYDIDFVPPSPEEIISTASSSLKCSSMLKDLDDSDKEKDILSTSKDLS-KPEEMTTPKSDLGTNEDCDAQQTS-LQQQLIRVMEHICKLVDTVPIDELKALT--CGDKLLQQRDIRRKLLAEAGFNRN----DVNLLGSLWR----HRPDSLDNTVQCDSCPVGHPGKELNSPYLPSHSLSTEE--------CLPT---TASGKTGFSATPKSLSERPPLNSHLQKSFVS-SNWAETPRTES----------RTESTYFPGSVLTSTTVKDESKHVASGRDIEREVQASYD---------------------------IDNFNIDDFDDDDDDD-WENIMHNFSVSKSSTAAYPPIKEGGPVKSLSERISSAKAKFLPVASTAQNKNLSESIQNCSDK-FAQNLSSKNPKHEHFQSLNFPHTKEMMKIFRKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPG----VTIVISPLRSLIVDQVQKLTSFDIPATYLTGDKTDSEAANIYLQLSKKDPIIKLLYVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQRFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVALDCLEWIRKHHPYDSGIIYCLSRKECDTMADTLQREGLAALAYHAGLSDSARDEVQHKWINQDNCQVICATIAFGMGIDKPDVRFVVHASLPKSVEGYYQESGRAGRDGEISHCVLFYTYHDVTRLKRLIMMEKDGNYHTRETHVNNLYSMVHYCENITECRRIQLLAYFGEKGFNPDFCKKHPDVSCDNCCKTK--DYKTKDVTDDVKNIVRFVQEHSSSPGTR---NIGPAGRFTLNMLVDIFLGSKSAKVQSG------IFGKGSAYSRHNAERLFKKLILDKILDEDLYINANDQPIAYVMLGTKAHSVLSGHLKVDFMETENSSSVKKQK--------AAVAH-VSQRDEAVMKCLGELADVCKLLGKVFGVHYFN-IFNTATLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEIIPVLQKYAEWTLPAEGGSPGS-----RGSRRSTPEETEEEEA---------VSSHYFANQTRNERKRKKVSASQKPKRRRTSYGGGFRAKGGSTTCRKPSSKSKFSG--VTGSRSASCASQATS--AASRKLGIMAPPKP--VNRPFLRPAYAFS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54132-1", "uniprot_id": "BLM_HUMAN", "id": "P54132-1", "name": "RecQ-like DNA helicase BLM", "aln": "-----------MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKTSSDNNVSVTNVSVAKTPVLRNKDVNVTED--FSFSEP-LPNTTNQQRVKDFFKNAPAGQETQR-GGSKSLLPDFLQTPKEVVCTTQNTPTVKKSR--DTALKKLEFSSSPDSLSTINDWDDMDDFDTSETSKSFVTPPQSH-FVRVSTAQKSKKGKRNFFKAQLYTTNTVKTDLPPPSSESEQIDLTEEQKDD---------SEWLSSDVICIDDGPIAEVHINEDAQESDSLKTHLEDERDNSEKKKNLEEAELHSTEKVPCIEFDDDDYDTDFVPPSPEEIISASSSSSKCLSTLKDLDTSDRKEDVLSTSKDLLSKPEKMSMQELNPETSTDCDARQIS-LQQQLIHVMEHICKLIDTIPDDKLKLLD--CGNELLQQRNIRRKLLTEVDFNKS----DASLLGSLWR----YRPDSLDGPMEGDSCPTGNSMKELNFSHLPSNSVSPGD--------CLLT---TTLGKTGFSATRKNLFERPLFNTHLQKSFVS-SNWAETPRLGK----------KNESSYFPGNVLTSTAVKDQNKHTASINDLERETQPSYD---------------------------IDNFDIDDFDDD---DDWEDIMHNLAASKSSTAAYQPIKEGRPIKSVSERLSSAKTDCLPVSSTAQNINFSESIQNYTDK-SAQNLASRNLKHERFQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPG----VTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTK--DYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQSG------IFGKGSAYSRHNAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQK--------ALVAK-VSQREEMVKKCLGELTEVCKSLGKVFGVHYFN-IFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIP---------VSSHYFASKTRNERKRKKMPASQRSKRRKTASSG-SKAKGGSATCRKISSKTKSSS--IIGSSSASHTSQATS--GANSKLGIMAPPKP--INRPFLKPSYAFS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YUA3-1", "uniprot_id": "A0A8M6YUA3_DANRE", "id": "A0A8M6YUA3-1", "name": "RecQ-like DNA helicase BLM", "aln": "MTNERASCKYAMSSLPQNNLKEHLERHNN-AAQNKLSLLKPKPGGFCFKKKSSSGISKVEVPQKVTGSSVLANRSVNIPSN--FEVTKNPVTFSQKPERVAPKVNFFTAPSKPKTNTVNPLANPFALNKTPLVQSTIKALPKSAALPKDSTNDQTVELKHDISQLS-FNEWDDLDDFETPVKSRVASPVAGTS-TKKPSVSDQNTSSSCSSKCEETKVNEESQATETITAPKDVLSAANGVSTET---------AEREPEDSPIKKSKRPKKSVQHTALLSDTEDEEIIHCVSPDTNQKNFKSVAVAEKDKWGEPNVIDSDDCEENNHYEGFEDFIPPSPIPEEIS-----LSVSDKEK--SSSEPVTPANKKESSRSASGLPAPLDQSAKGLKGADDALFSVMESICCLVDTIPEHELIALT--CGTELLLQRAHRKRILAKGGSSRTSHSDSVSTPGFLNRPTFGVTPSNLTSLTPVTSGKREGVKTGFSFRKSIASVMSVGDESVFEDSDCIINGVETPGGTWNPNSSTKISAGRDTFNGSIQTLSKPESKTDKCYSRLS----------FNESSNQTDLFYSPKRVDSGSRNADSSVEINIAGSSSLRTGAEPVDD-----------------FLLDDFDIDDFDENDIPDYYEEPPSVLESRNNSGVKTPSVQEGGSSKSFER------KTFTPPAPKSIKTPNPEPLY-------------RNPAHDRFRGFNFPHSPEMMKIFHKKFGLHQFRFNQLEAINASLLGEDTFVLMPTGGGKSLCYQLPACVSAG----VTVVISPLRSLIVDQVQKLTTLDICATSLSGDKKDSEAARIYMQLSRKDPAIKLLYATPEKVCASGRMISALQNLYERGLLARLVIDEAHCVSQWGHDFRPDYKRLHELRRMFPNVPIMALTATATPRVQKDILNQLAMTRPQVFTMSFNRNNLKYSVLPKKPKKVDEECIQWIKKYYPRDSGIVYCLSRNDCDTLADSLQRAGIAALAYHAGLSDSDREYVQNKWINQDGCQVMCATIAFGMGIDKPDVRYVIHASLPKSVEGYYQESGRAGRDGEISHCVLFYSYSDVIRIKRLIAMDKDGNQQSKATHINNLHSMVHFCENVAECRRIQLLAYFGEHTFNTSFCKEHPEVICDNCARPN--KYKSRNVTDDVKKIARFVQDNCEKVGNRYG-KSAQQNRLTLNMLVEIFLGSKSARIQTG------MFGVGAAYSKHNAERLFKKLVLDNVLMEDLYITNSGQAVAYISAGPKAMSVLNGCMQVEFHETESASSIRKHR--------ASVCEKVSKREEMVKKCLGELNDLCKKLGKVFGIHYYN-IFSTATLKKIAETLSADPEVLLQIDGVTEDKLEKYGAEFIELLQKYSEWQLPAEAQAESSGWIDTTRGHQNDEDDNDDDDEG-----GGDVTSTYFRSNSGRGAKRKQGSYSRKPKRRKGSSGQNSSAKGGYSSNWSSSRGGGRGGGYRGGSRGAGRGSRSAPSGSAAKRPGFMSLPTPQAAARPFLKPSFSHL---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGI8-1", "uniprot_id": "BLM_DROME", "id": "Q9VGI8-1", "name": "RecQ-like DNA helicase Blm", "aln": "------MSKKPVAQRKQLTLSSFIGLDGNSQSQPKSRAASVRSKPPAVYNPIFLDASSSDDETTEISSQSNNGTIATKKSS--RDPRTAKLKKHTYLDLSVSPLAKLSAKKYARDSPKKPTSLDLSVSPLAELLAKKSDRDSPKKPVQNENSYTYRGLSESPVENKSIGDTLRKPPQKERKTSIVWLSDSPEK-KVTQNERKILDSPLQRFSFEDFPNKENGNRHHLLTLPDSPPPPQPVKKPEK---------TMWQNETKTIQDKDSPANPLVSNNLASISTLLDSSRAPNTYKGSSRNLFEDSPEKSGSGE-QGYKLGSAKENEIPTKPATASLERNSVTSSPSPAAPLKPRYSVAFDNSLADYLKDLAQNDNFSIDPNKQNTETLKSTLGFFRNTYVELMEKYCSLIDQIPAMHFNEIAGFQPNTFLKLKVMRQKFKARTQLVQNSLDKKESQLKAEQEALEKEEIEMQAEQAQQTVLSSSSPEKSRPIMPLPKVQEIKDEK--IPNRNQLIHDLCGEPDNFSPPSSPRDTQLIPKRQQLINDLCGEPDDFSPPSKQNDPHLLRKCEELVHDLCEEPDDYLAQSMMLDGDLEEEQLNGPTQGTTTSGMDDDEDDLEGLLAEIEDEHQKMQGRRSEFNGYSYKELEAVKVKEKHKETPINISLDDDGFPEYDEAMFEQMHSQAAANKSRVSSAGPSTSKSVVPTKQTSALHSQKLSGNFHANVHNDGITGEFDGQKFEHSTRLMHGLSYSFGLKSFRPNQLQVINATLLGNDCFVLMPTGGGKSLCYQLPAILTEG----VTIVISPLKSLIFDQINKLASLDICAKSLSGEQKMADVMAIYRDLESQPPMVKLLYVTPEKISSSARFQDTLDTLNSNNYISRFVIDEAHCVSQWGHDFRPDYKKLGVLKKRFPNVPTIALTATATPRVRLDILAQLNLKNCKWFLSSFNRSNLRYRVLPKKGVSTLDDISRYIRSKPQHFSGIIYCLSRKECDETSKKMCKDGVRAVSYHAGLTDTDRESRQKDWLTG-KMRVICATVAFGMGIDKPDVRFVLHYSLPKSIEGYYQEAGRAGRDGDVADCILYYNYSDMLRIKKMLDSDKALQYNVKKIHVDNLYRIVGYCENLTDCRRAQQLDYFGEH-FTSEQCLENRETACDNCINKR--AYKAVDALEHARKAARAVKDLCSG-----------RSRFTLLHIADVLKGSKIKKIIDFNHHKTPHHGVLKDWDKNDVHRLLRKMVIDGFLREDLIFTN-DFPQAYLYLGNNISKLMEGTPNFEFAVTKNAKEAKAAVGSVSDGATSSTADGQSGMREIHERCYTDLLDLCRTIASQRNVTMAS-IMNIQALKSMAETLPITEKDMCSIPHVTKANFDKYGAKLLEITSNYASEKLLMQAVLDEEEEQAAAKQRPSTSGWNNESVDW-----DMAVASQGNANTSG-ASGFNSFRAGKRKKIYKSGASKRYKTSTTSPAARKTTSARGRGG--RAGAKRAESSASSAS--------GWKSKKTGNSFGFDLMPLPGSK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35187-1", "uniprot_id": "SGS1_YEAST", "id": "P35187-1", "name": "ATP-dependent helicase SGS1", "aln": "-----------MVTKPSHNLRREHKWLKETATLQEDKDFVFQAIQKHIANKRPKTNSPPTTPSKDECGPGTTNFITSIPASGPTNTATKQHEVMQTLSNDTEWLSYTATSNQYADVPMVDIPASTSVVSNPRTPNGSKTHNFNTFRPHMASSLVENDSSRNLGSRNNNKSVIDNSSIGKQLENDIKLEVIRLQGSLIMALKEQSKLLLQKCSIIESTSLSEDAKRLQLSRDIRPQLSNMSIRIDS--------LEKEIIKAKKDGMSKDQSKGRSQVSSQDDNIISSILPSPLEYNTSSRNSNLTSTTATTVTKALAITGAKQNITNNTGKNSNNDSNNDDLIQVLDDEDDIDCDPPVILKEGAP-HSPAFPHLHMTSEEQDELTRRRNMRSREPVNYRIPDRDDPFDYVMGKSLRDDYPDVE--REEDELTMEAEDDAHSSYMTTRDEEKEENELLNQSDFDFVVNDDLDPTQDTDYHDNMDVSANIQESSQEGDTRSTITLSQN-------KNVQVILSSPTAQSVPSNGQNQIGVEHIDLLEDDLEKDAILDDSMSFSFG-------------RQHMPMSHSDLELIDSEKENEDFEEDNNNNGIEYLS-----------------------------DSDLERFDEER--ENRTQVADIQELDNDLKIITERKLTGDNEHPPPSWSPKIKREKSSVSQKDEEDDFDDDFS-------LSDIVSKSNLSSKTNGPTYPWSDEVLYRLHEVFKLPGFRPNQLEAVNATLQGKDVFVLMPTGGGKSLCYQLPAVVKSGKTHGTTIVISPLISLMQDQVEHLLNKNIKASMFSSRGTAEQRRQTFNLFING--LLDLVYISPEMISASEQCKRAISRLYADGKLARIVVDEAHCVSNWGHDFRPDYKELKFFKREYPDIPMIALTATASEQVRMDIIHNLELKEPVFLKQSFNRTNLYYEVN-KKTKNTIFEICDAVKSRFKNQTGIIYCHSKKSCEQTSAQMQRNGIKCAYYHAGMEPDERLSVQKAWQAD-EIQVICATVAFGMGIDKPDVRFVYHFTVPRTLEGYYQETGRAGRDGNYSYCITYFSFRDIRTMQTMIQKDKNLDRENKEKHLNKLQQVMAYCDNVTDCRRKLVLSYFNED-FDSKLCHKN----CDNCRNSANVINEERDVTEPAKKIVKLVESIQNE-------------RVTIIYCQDVFKGSRSSKIVQANHDTLEEHGIGKSMQKSEIERIFFHLITIRVLQEYSIMNNSGFASSYVKVGPNAKKLLTGKMEIKMQFTISAPNSRPSTSSSFQANEDNIPVIAQKSTTIGGNVAANPPRFISAKEHLRSYTYGGSTMGSSHPITLKNTSDLRSTQELNNLRMTYERLRELSLNLGNRMVPPVGNFMPDSILKKMAAILPMNDSAFATLGTVEDKYRRRFKYFKATIADLSKKRSSEDHEKYDTILNDEFVNRAAASSNGIAQSTGTKSKFFGANLNEAKENEQIINQIRQSQLPKNTTSSKSGTRSISKSSKKSANGRRGFRNYRGHYRGRK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* : : . : . . .. . . . . : . . . . . . . . : : . . .. . . . :. . . : ::. . : * . : . . : . :. : : : . : . . . . . :: : : .. . . . : .. . . .: : .:: : * * ** ***:.:**:* *:* *:**************** :. * .*:***** **: **:::* . :* *. ::. . : : : :.*:* :** :.:* : ::. * ::*:*:*******:****** ***.: ::: :*.:* :******. :*: **: :* : . : **** ** * * ** .. : ::. :**:** *:..*: : : : *: . ****: * *: * :*:***:************:* * ::*:::******:*******: : *: ::.: *: :: :: :* : . : *.::* :: :*:*:::*** * **.*. * .. * : **** . : :. : .:. : *:. . *.*: ::: **: :: .* .: : .*:: ::: .* * :. . . :*: * : .:: * :..: * .: . : . . : . . . :. .: :: . :* .: : . :. . ::. ::. : . . : . . :. . . . . . :. : . : ", "identical_positions": 171, "similar_positions": 292, "identity": "11.04%" }, { "cls_id": "homologset.agr.SGD:S000004804", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6H6A9-1", "uniprot_id": "RBG1L_MOUSE", "id": "A6H6A9-1", "name": "Rab GTPase-activating protein 1-like", "aln": "----------------------------------------------------------------------------------------MEVRASFQKVSGSSDSVATLNSEEFVLVSQHTDATSIKDDG----KPQLKIASNGDEQ-LEKAMEEILRDS------------EKGQSGLPVDCQGSSEISDCPFGDVPASQTTKPPLQLILDPSNTEISTPRPSSPSRFPEEDSVLFNKLTYLGCMKVSSPRSEVEALRAMATMRAS----------------------------------------------------------SQYPFAVTLYVPNVPEGSVRIIDQSSNVEIASFPIYKVLFCARGHDGTAESNCFAFTESSHGSEEFQIHVFS----------------CEIKEAVSRILYSFCTAFKRSSRQVSDVKDSVIP-TPDSDVFTFSVSLEVKEDD-GKGNFSPVPKDRDKFYFKIKQGIEKKVVITVQQLSNKELAIERCFGMLLSPGRNVKNSDMHLLDMESMGKSYDG--------RAYVITGMWNPNAPIFLALNEETPKDKRVYMTVAVD-----------MVVTEVVEPVRFLLETVVRVYPANER-FWYFSRKTFTETFFMRLKQSEGKGHSSAGDAIYEVVSLQRESDKEEPITPTSAGGPMS-----------PQEDEAEEESDNELSSGTGDVSKDCPEKILYSWGELLGRWHNNLGGRPKGLFTLVKSGVPEALRAEVWQLLAGCHDNQEMLDKYRILITKDSAQ-------------------------------------------------------------------------------------------------ESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVFDEDIGYC-----QGQSFLAAVLLLHMPE---------EQAFCVLVTIMYGYKLRDLYRNN-FEDLHCKFYQLEKLMQEQLP---DLYS-----HFCDLNLEAHMYAS-----------QWFLTLFTAKFPLCMVFHIIDLLLCEGLNII-FHVALALLKTSKEDLL--QADFEGALKFFRVQLP-KRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQAMRENQ--------LQQEDPMDRYKFVYL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AXS5-1", "uniprot_id": "A0A8I6AXS5_RAT", "id": "A0A8I6AXS5-1", "name": "Rab GTPase-activating protein 1-like", "aln": "----------------------------------------------------------------------------------------MEVRASLQKVSGSPDSAATLNSEEFVLVPQHTDDTSIKDDG----KPQLKIASNGDEQ-LEKAMEEILRDS------------EKGQSSLPVDGQGSSEISDHSFGDVPASQSNKPPLQLILDPSNTEISTPRPSSPSGFPEEDSVLFNKLTYLGCMKVSSPRSEGEALRAMATMRAS----------------------------------------------------------SQYPFAVTLYVPNVPEGSVRIIDQSSNVEIASFPIYKVLFCARGHDGTTESNCFAFTESSHGSEEFQIHVFS----------------CEIKEAVSRILYSFCTAFKRSSRQVSDVKDSIIP-TPDSDVFTFSVSLEVKEDD-GKGNFSPVPKDRDKFYFKIKQGIEKKVVITVQQLSNKELAIERCFGMLLSPGRNVKNSDMHLLDMESMGKSYDG--------RAYVITGMWNPNAPIFLALNEETPKDKRVYMTVAVD-----------MVVTEVVEPVRFLLETVVRVYPANER-FWYFSRKTFTETFFMRLKQSEGKGHSSAGDAIYEVVSLQRESDKEEPVTPTSGGGPAS-----------PQEDEAEEESDNELSSGTGDVSKDCPEKILYSWGELLGRWHNNLNARPKGLPTLVKSGVPEALRAEVWQLLAGCHDNQAMLDKYRILITKDSAQ-------------------------------------------------------------------------------------------------ESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYC-----QGQSFLAAVLLLHMPE---------EQAFCVLVNIMYKYKLRDLYKNN-FEDLHCKFYQLEKLMQEQLP---DLYS-----HFCDLNLEAHMYAS-----------QWFLTLFTAKFPLCMVFHIIDLLLCEGLNII-FHVALALLKTSKEDLL--QADFEGALKFFRVQLP-KRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQAMRENQ--------LQQEDPMDRYKRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKAD-------------VLSKELLFTKQRLVETEEE--------------KRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTR---------------LEKQQAASKEELEAVKGKMMACKHCSDIFSKEGAGK----PVAISREDQGLEADDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPPQAPQPPKEST-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5R372-1", "uniprot_id": "RBG1L_HUMAN", "id": "Q5R372-1", "name": "Rab GTPase-activating protein 1-like", "aln": "----------------------------------------------------------------------------------------MEVRASLQKVSGSSDSVATMNSEEFVLVPQYADDNSTKHEE----KPQLKIVSNGDEQ-LEKAMEEILRDS------------EKRPSSLLVDCQSSSEISDHSFGDIPASQTNKPSLQLILDPSNTEISTPRPSSPGGLPEEDSVLFNKLTYLGCMKVSSPRNEVEALRAMATMKSS----------------------------------------------------------SQYPFPVTLYVPNVPEGSVRIIDQSSNVEIASFPIYKVLFCARGHDGTTESNCFAFTESSHGSEEFQIHVFS----------------CEIKEAVSRILYSFCTAFKRSSRQVSDVKDSVIP-TPDSDVFTFSVSLEVKEDD-GKGNFSPVPKDRDKFYFKLKQGIEKKVVITVQQLSNKELAIERCFGMLLSPGRNVKNSDMHLLDMESMGKSYDG--------RAYVITGMWNPNAPVFLALNEETPKDKQVYMTVAVD-----------MVVTEVVEPVRFLLETVVRVYPANER-FWYFSRKTFTETFFMRLKQSEGKGHTNAGDAIYEVVSLQRESDKEEPVTPTSGGGPMS-----------PQDDEAEEESDNELSSGTGDVSKDCPEKILYSWGELLGKWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYRILITKDSAQ-------------------------------------------------------------------------------------------------ESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYC-----QGQSFLAAVLLLHMPE---------EQAFCVLVKIMYDYGLRDLYRNN-FEDLHCKFYQLERLMQEQLP---DLHS-----HFSDLNLEAHMYAS-----------QWFLTLFTAKFPLCMVFHIIDLLLCEGLNII-FHVALALLKTSKEDLL--QADFEGALKFFRVQLP-KRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQ--------LQQEDPMDRYKFVYL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IFA0-1", "uniprot_id": "A0AC58IFA0_DANRE", "id": "A0AC58IFA0-1", "name": "", "aln": "----------------------------------------------------------------------------------------MDDSSSLGRVSGSTESVSTVTSEEFVLVPPSAGGSPSSSEG----RPRLKMSWNGSEQ-LERAMEEVLDDV------------ADGAG--AEQEKGCTQIR-------PPS----------LDTAPHESSAALLESPT-VPEEESVQFSKLSYLGCTWVKAPRSETEAQKAMATLRAE----------------------------------------------------------SAIPIPVILHVPNGSDGCVRIVDQASGTEIASFPIYKVLFCARGCEGSVESDCFSFTESYRSSEDFQIHVFS----------------CHIKEAVSRILYSFSTAFKRSAKAATEMQDSPLPLSPDSDVFTFSVSLEVREDD-GKGNFSPVPKDRDKYYFKLRQGVQKKVSVVVQQLNNKELVIERCFGMLLSPGQKVRNSDMHLLDMESMGKNADG--------KAYVITGIWNPNTPAFQPLNEDTPKDKQVYMTVAVD-----------LVVTEVVEPVRFLMEALVRVYPANER-FWYFSRKAFCETFYLKLKQGSVKG--SQDDMMYEVVSLEKHSECG---SQARGRLQSP-----------TEEEEPEEDSDSEISSGTGDVSKDCPEKILESWGGILNRWQGNLLTRPKGLSALVKPGIPEALRAEVWQLLSGCHNDQALLEQYRILITKESAQ-------------------------------------------------------------------------------------------------EAVITRDIHRTFPAHDYFKDSGGDGQDSLYKICKAYSVYDEEIGYC-----QGQSFLAAVLLLHMPE---------EQAFCVLVKIMFNYGLRELYRNN-FEDLHCKFYQLERLLQELLP---DLWS-----HFQELNLEAHMYAS-----------QWFLTLFTAKFPLCMVFHITDLLLCEGLNII-FNVALALLKTSKEDLL--QADFEGALKFFRVQLP-KRYRAAENARRLMEQACNIKVPTKKLKKFEKEYQSLRESQ--------LQQEDPIDRYQRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKAD-------------VLNKELLNTKQRLVETEEE--------------KRRQEEETAQLKEVFRRELEKAEQEIKKTTAIIAEYKQICSQLSTR---------------LEKQQASTKEELDIVKAKVMACERCREVFSKDGPLQ----IPPVSQDNRDTDLDEEKDSLKAQLRELELELAQTKLQLVEAKCKIQELEHQRGVLMTEVQAAKNSWFSKTLGSLKNSASNQSPSSPKEGP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2AWA9-1", "uniprot_id": "RBGP1_MOUSE", "id": "A2AWA9-1", "name": "Rab GTPase-activating protein 1", "aln": "----------------------------------------------------------------------------------------MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIVGNGSEQQLQKELADVLMDPPMDDQPG-----ERSQLDGEGDGPLSNQLSASSTIN-PVPLVGLPKPEMSLPVKPGQGDSEVSSPFTPVADEDSVVFNKLTYLGCASVNAPRSEVEALRMMSILRSQ----------------------------------------------------------CQISLDVTLSVPNVSEGTVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNAELFRIHVFR----------------CEIQEAVSRILYSFATAFRRSAKQTP-LSATAAPQTPDSDIFTFSVSLEIKEDD-GKGYFSAVPKDKDRQCFKLRQGIDKKIVICVQQTANKELAIERCFGLLLSPGKDVRNSDMHLLDLESMGKSSDG--------KSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVD-----------LVITEVQEPVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQKEKKNNADTLYEVVCLESESERERRKTTASPSVRLPQSGSQSSMIPSPPEDDEEEDNDEPLLSGFGDVSKECAEKILETWGELLSKWHLNLSVRPKQLSSLVRSGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKESPQ-------------------------------------------------------------------------------------------------DSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYC-----QGQSFLAAVLLLHMPE---------EQAFSVLVKIMFDYGLRELFKQN-FEDLHCKFYQLERLMQEYIP---DLYN-----HFLDISLEAHMYAS-----------QWFLTLFTAKFPLYMVFHIIDLLLCEGISVI-FNVALGLLKTSKDDLL--LTDFEGALKFFRVQLP-KRYRSEENAKRLMELACNTKISQKKLKKFEKEYHTMREQQ--------AQQEDPIERFERENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKAD-------------ALNKELLMTKQKLIDAEDE--------------KRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSER---------------LEKQQTANKVEIEKIRQKVDDCDRCRDFFNKEGRVK----GISSAKGVSDEDTDEEKETLKNQLREMELELAQTKLQLVEAECKIQDLEHHLGLALSEVQAAKKTWFNRTLSSIKTATGVQGKETC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZX42-1", "uniprot_id": "D3ZX42_RAT", "id": "D3ZX42-1", "name": "Rab GTPase-activating protein 1", "aln": "----------------------------------------------------------------------------------------MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIVGNGSEQQLQKELADVLMDPPMDDQPGM----ERSHLDGEGDGPLSNQLSASSTIN-PVPLVGLQKPEMSLPVKSGQGDSEVSSPFTPVADEDSVVFNKLTYLGCASVNAPRSEVEALRMMSILRSQ----------------------------------------------------------CQISLDVTLSVPNVSEGTVRLLDPQINTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNAELFRIHVFR----------------CEIQEAVSRILYSFATAFRRSAKQTP-LSATAAPQTPDSDIFTFSVSLEIKEDD-GKGYFSAVPKDKDRQCFKLRQGIDKKIVICVQQTANKELAIERCFGLLLSPGKDVRNSDMHLLDLESMGKSSDG--------KSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVD-----------LVITEVQEPVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQKEKKNNADTLYEVVCLESESERERRKTTASPSVRLPQSGSQSSMIPSPPEDDEEEDNDEPLLSGFGDVSKECAEKILETWGELLSKWHLNLNVRPKQLSSLVRSGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKESPQ-------------------------------------------------------------------------------------------------DSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYC-----QGQSFLAAVLLLHMPE---------EQAFSVLVKIMFDYGLRELFKQN-FEDLHCKFYQLERLMQEYIP---DLYN-----HFLDISLEAHMYAS-----------QWFLTLFTAKFPLYMVFHIIDLLLCEGISVI-FNVALGLLKTSKDDLL--LTDFEGALKFFRVQLP-KRYRSEENAKRLMELACNTKISQKKLKKFEKEYHTMREQQ--------AQQEDPIERFERENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKAD-------------ALNKELLMTKQKLIDAEDE--------------KRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSER---------------LEKQQTANKVEIEKIRQKVDDCDRCRDFFNKEGRVK----GASSVKGVSDEDTDEEKETLKNQLRELELELAQTKLQLVEAECKIQDLEHHLGLALSEVQAAKKTWFNRTLSSIKTATGVQGKETC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y3P9-1", "uniprot_id": "RBGP1_HUMAN", "id": "Q9Y3P9-1", "name": "Rab GTPase-activating protein 1", "aln": "----------------------------------------------------------------------------------------MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIVGNGSEQQLQKELADVLMDPPMDDQPGEKELVKRSQLDGEGDGPLSNQLSASSTIN-PVPLVGLQKPEMSLPVKPGQGDSEASSPFTPVADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRSQ----------------------------------------------------------CQISLDVTLSVPNVSEGIVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNAELFRIHVFR----------------CEIQEAVSRILYSFATAFRRSAKQTP-LSATAAPQTPDSDIFTFSVSLEIKEDD-GKGYFSAVPKDKDRQCFKLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNSDMHLLDLESMGKSSDG--------KSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVD-----------LVITEVQEPVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQRERKNNTDTLYEVVCLESESERERRKTTASPSVRLPQSGSQSSVIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILETWGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKESPQ-------------------------------------------------------------------------------------------------DSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYC-----QGQSFLAAVLLLHMPE---------EQAFSVLVKIMFDYGLRELFKQN-FEDLHCKFYQLERLMQEYIP---DLYN-----HFLDISLEAHMYAS-----------QWFLTLFTAKFPLYMVFHIIDLLLCEGISVI-FNVALGLLKTSKDDLL--LTDFEGALKFFRVQLP-KRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQ--------AQQEDPIERFERENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKAD-------------ALNKELLMTKQKLIDAEEE--------------KRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSER---------------LEKQQTANKVEIEKIRQKVDDCERCREFFNKEGRVK----GISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQLVEAECKIQDLEHHLGLALNEVQAAKKTWFNRTLSSIKTATGVQGKETC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97366-1", "uniprot_id": "EVI5_MOUSE", "id": "P97366-1", "name": "Ecotropic viral integration site 5 protein", "aln": "----------------------------------------------------------------------------------------------------------MVTTKMTAAFRNPNRRQVATDKVAEKLSSTLSWVKNTVSHTVSQMASQVASPSA-------------------------------------------------SLHTTSSSTTLSTPTQSPSSPSK-LSPDDLELLAKLEEQNRLIETDSKSLRSVNG------------------------------------------------------------SRRNSGSSLVSSSSASSNLSHLEEDS------WILWGRIVNEWDDVRKKKEKQVKELVRKGIPHHFRAIVWQ----------------LLCNAQSMTIKDQYSELLKMTSPCEKLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDRELVTVRAVLSSLDCCCMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEYLP--------ELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATR-----------IFDIFMSEGLEIVFRVGLALLQMNQAELMQLDMEGMLQHFQKVIPHQFDGGPEKLIQSAYQVKYNSKKMKKLEKEYTTIKT------------------KEMEEQGEIKRLRTENRLLKQRIETLEK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------HKCSSTYNEDFVLQLEKELVQARLSEAESQCALKEM-----QDKVLDIEKKNNSFPD---------ENNIARLQEELIAVKLREAEAIMGLKELRQQVRTLEEHWQRHLA---RTSG-----RWKDPPKKNAVN-------------ELQDELMSIRLREAETQAEIREMKQRMMEME-TQNQINSNQLRRAEQE--VNSLQEKVCSLSVKNKGLLAQLSEAKRRQAEIECKNKEEVMAVRLREADSIAAVAEL--------QQHIAELEIQKEEGK--LQGQLNR-SDSNQYIRELKDQIAELTHELRCLKGQRD--------------FSSRPPFDGIHIVSHLIG----------------DDELFHSSDEDFID---------------SSLQESAIGFPLHRKS----------------GPMSLNPALADG----------------SESEA---------------------------EDGMLGPQESDPEAPQKQPPQR-ESYSTTV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZM01-1", "uniprot_id": "A0A8I5ZM01_RAT", "id": "A0A8I5ZM01-1", "name": "", "aln": "------------------------------------------------------------------------------MQLVFFFPFFIVLIKMPLVQQGILTFTGSASVYLAQSLRHSSCLWVATDKVAEKLSSTLSWVKNTVSHTVSQMASQVASPSA-------------------------------------------------SLHTTSSSTTLSTPTQSPSSPSK-LSPDDLELLAKLEEQNRLIETDSKSLRSVNG------------------------------------------------------------SRRNSGSSLVSSSSASSNLSHLEEDS------WILWGRIVNEWDDVRKKKEKQVKELVRKGIPHHFRAIVWQ----------------LLCDAQTMPVKDQYSELLKMTSPCEKLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLLQMPEEEAFCVFFKLMQDYRLRELFKPSMAELGLCMYQFECMIQEYLP--------ELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATR-----------IFDIFMSEGLEIVFRVGLALLQMNQAELMQLDMEGMLQHFQKVIPHQFDGGPEKLIQSAYQVKYNSKKMKKLEKEYTTIKT------------------KEMEEQGEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQ------EAEENYLIKRELATIKQQTDAARAKLEQAESTIRELQH--------------------------------------------------------------------------------------------------------HRHWHKCSSTYNEDFVLQLEKELVQARLSEAESQCALKEM-----QDKVLDIEKKNNSFPD---------ENNIARLQEELIAVKLREAEAIMGLKELRQQVRDLEEHWQRHVA---RTSG-----RWKDPPKRNAVS-------------ELQGELMSIRLREAETQAEMREMKQRMMEME-TQNQINSNQLRRAEQE--VTSLQEKVCSLSLKNKGLLAQLSEAKRRQAEIECKNKEEVMAVRLREADSIAAVAEL--------QQHIAELEIQKEEGK--LQGQLNR-SDSKQYIRELKDQIAELTHELRCLKGQRD--------------FSSRPPFDGIHIVSHLIG----------------DDESFHSSDEDFID---------------SSLQESAIGFPLHRKS----------------GPVSLNPALADG----------------SESEA---------------------------EDGVLGTQESDPEAPEKQIPQR-ESYSTTV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60447-1", "uniprot_id": "EVI5_HUMAN", "id": "O60447-1", "name": "Ecotropic viral integration site 5 protein homolog", "aln": "----------------------------------------------------------------------------------------------------------MVTNKMTAAFRNPSGKQVATDKVAEKLSSTLSWVKNTVSHTVSQMASQVASPST-------------------------------------------------SLHTTSSSTTLSTPALSPSSPSQ-LSPDDLELLAKLEEQNRLLETDSKSLRSVNG------------------------------------------------------------SRRNSGSSLVSSSSASSNLSHLEEDS------WILWGRIVNEWEDVRKKKEKQVKELVHKGIPHHFRAIVWQ----------------LLCSAQSMPIKDQYSELLKMTSPCEKLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEHLP--------ELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATR-----------IFDIFMSEGLEIVFRVGLALLQMNQAELMQLDMEGMLQHFQKVIPHQFDGVPDKLIQAAYQVKYNSKKMKKLEKEYTTIKT------------------KEMEEQVEIKRLRTENRLLKQRIETLEK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------HKCSSNYNEDFVLQLEKELVQARLSEAESQCALKEM-----QDKVLDIEKRNNSLPD---------ENNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRHLA---RTTG-----RWKDPPKKNAMN-------------ELQDELMTIRLREAETQAEIREIKQRMMEME-TQNQINSNHLRRAEQE--VISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNKEEVMAVRLREADSIAAVAEL--------RQHIAELEIQKEEGK--LQGQLNK-SDSNQYIGELKDQIAELNHELRCLKGQRG--------------FSGQPPFDGIHIVNHLIG----------------DDESFHSSDEDFID---------------NSLQETGVGFPLHGKS----------------GSMSLDPAVADG----------------SESET---------------------------EDSVLETRESNQVVQKERPPRRRESYSTTV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ATD7-1", "uniprot_id": "A0A8M3ATD7_DANRE", "id": "A0A8M3ATD7-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------MVATDKVTGKLSSTLSWVKNSVSHTVSQMASQVATPS--------------------------------------------------SLHTTVASSTASLSSPSSASPTQ-LSPDDVELLAKLEEQNRLLETDSKSLRSVNG------------------------------------------------------------SRRNSGSSLVSSSSASSNLSHLEEDS------WILWGRIVNEWEDVRKKKEKQLKELVRKGVPHHFRAIVWQ----------------LLCNAQNLPIKEQYSELLKMTSPCEKLIRRDIARTYPEHEFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVKLMQEYRLRELFKPSMAELGLCMYQFECMIQEQLP--------ELHVHFQAQSFHTSMYASSWFLTIFLTSFPLPVATR-----------IFDIFMCEGLEIVFRVGMAILQMNQAELMQLDMEGMLQHFQKVIPHQLDSGPDKVIQAAYQVKYNAKKMKKLEKEYTTIKT------------------KEMEEQVEIKRLRTENRLLKQRIDTLEKESASLADRLIQGQVTRAQ------EAEENYLVKRELATVKQHIEETSVQLEQAQSTIRQLQQ--------------------------------------------------------------------------------------------------------P--FAKGNPRYTEESILQLERELVQARLKEAESQCALKEM-----QDKILYMEQRNTSLPD---------ENNVVRLQEELIGVKLREAEALTGLKELRQQVRDLEEHWQRHLA---RTAG-----RWKDSPRKNAAS-------------ELQDELMSVRLREAEAQAELRETRQRMLELE-TQNQIHSNQLRRAELE--ARNLQDRLHVLSNQNKMLHSELQETKRKQAEIECKNKEEVMAVRLREADNIAAMAEL--------QQQISELEIQKEEGK--VQGQLNN-TDSSQYIRDLKDQIADLKHEIRCLRGHQG--------------LPNQHTFDGIHIVNHYGG----------------DNESYQSSDEDGVK---------------LSPHLT-----THQDR----------------GRITLHPNLED-----------------SESEG---------------------------DE------EGD--ALRLTVPSNVSHKTTTV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "H3BL92-1", "uniprot_id": "H3BL92_MOUSE", "id": "H3BL92-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MASPTL-------------------------------------------------SPDSSSQE-ALSAPTCSPTSDSENLSPDELELLAKLEEQNRLLEADSKSMRSMNG------------------------------------------------------------SRRNSGSSLVSSSSASSNLSHLEEDT------WILWGRIANEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQ----------------LLCSATDMPVKNQYSELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQLP--------DLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATR-----------VFDIFMYEGLEIVFRVGLALLQVNQTELMQLDMEGMSQYFQRVIPHQFDSCPDKLVLKAYQVKYNPKKMKRLEKEYAAMKS------------------KEMEEQIEIKRLRTENRLLKQRIETLEK-----------GQVTRAQ------EAEENYVIKRELAVVRQQCSSTAEDLQKAQSTIR------------------------------------------------------------------------------------------------------------QLQEQQENPRLTEDFVAHLETELEQSRLRETETLGALREM-----QDKVLDMEKRNSSLPD---------ENNVARLQEELKALKVREGEAVASARELKLQLQELSDTWQAHLS---RGG------RWKESPRKLVLG-------------ELQDELMTVRLREAQALADGREWRQRVVELE-TQDNIHRNLLNRVEAE--RAALQEKLQYLAAQNKGLQTQLSESRRKQAEAECKSKEEVMAVRLREADSMAAVAEM--------RQRIAELEIQREEGR--IQGQLNH-SDSSQYIRELKDQIEELKTEVRLLKGPPT--------------FEDPLAFDGLSLTRHLD------------------EDSLPSSDEELL-----------GVGVGVGAALQDPLYPLSPRD----------------ARFFRSLDRPA-----------------KDSEG---------------------------SS--------DSDADELATPYSNQGLDN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K1A4-1", "uniprot_id": "A0A0G2K1A4_RAT", "id": "A0A0G2K1A4-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MSLSTMASPTL-------------------------------------------------SPDSSSQE-ALSAPTCSPTSDSENLSPDELELLAKLEEQNRLLEADSKSMRSMNG------------------------------------------------------------SRRNSGSSLVSSSSASSNLSHLEEDT------WILWGRIANEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQ----------------LLCSATDMPVKNQYSELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQLP--------DLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATR-----------VFDIFMYEGLEIVFRVGLALLQVNQTELMQLDMEGMSQYFQRVIPHQFDSCPDKLVLKAYQVKYNPKKMKRLEKEYAAMKS------------------KEMEEQIEIKRLRTENRLLKQRIETLEKESAALADRLIQGQVTRAQ------EAEENYVIKRELAVVRQQCSSTAEDLQKAQSTIR------------------------------------------------------------------------------------------------------------QLQEQQENPRLTEDFVSHLETELEQSRLRETETLGALREM-----QDKVLDMEKRNSSLPD---------ENNVARLQEELKALKVREGEAVASARELKLQLQELSDTWQAHVS---RGG------RWKESPRKLVLG-------------ELQDELMTMRLREAQALADGREWRQRVVELE-TQDNIHRNLLNRVEAE--RAALQEKLQYLAAQNKGLQTQLSESRRKQAEAECKSKEEVMAVRLREADSMAAVAEM--------RQRIAELEIQREEGR--IQGQLNH-SDSSQYIRELKDQIEELKTEVRLLKGPPT--------------FEDPLAFDGLSLTRHLD------------------EDSLPSSDEELLG---------VGVGVGVGAALQDPLYPLSPRD----------------ARFFRSLDRPA-----------------KDSEG---------------------------SS--------DSDADELATPYSNQVLDN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96CN4-1", "uniprot_id": "EVI5L_HUMAN", "id": "Q96CN4-1", "name": "EVI5-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MASPTL-------------------------------------------------SPDSSSQE-ALSAPTCSPTSDSENLSPDELELLAKLEEQNRLLEADSKSMRSMNG------------------------------------------------------------SRRNSGSSLVSSSSASSNLSHLEEDT------WILWGRIANEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQ----------------LLCSATDMPVKNQYSELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQLP--------DLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATR-----------VFDIFMYEGLEIVFRVGLALLQVNQAELMQLDMEGMSQYFQRVIPHQFDSCPDKLVLKAYQVKYNPKKMKRLEKEYAAMKS------------------KEMEEQIEIKRLRTENRLLKQRIETLEK-----------GQVTRAQ------EAEENYVIKRELAVVRQQCSSAAEDLQKAQSTIR------------------------------------------------------------------------------------------------------------QLQEQQENPRLTEDFVSHLETELEQSRLRETETLGALREM-----QDKVLDMEKRNSSLPD---------ENNVAQLQEELKALKVREGQAVASTRELKLQLQELSDTWQAHLA---RGG------RWKESPRKLVVG-------------ELQDELMSVRLREAQALAEGRELRQRVVELE-TQDHIHRNLLNRVEAE--RAALQEKLQYLAAQNKGLQTQLSESRRKQAEAECKSKEEVMAVRLREADSMAAVAEM--------RQRIAELEIQREEGR--IQGQLNH-SDSSQYIRELKDQIEELKAEVRLLKGPPP--------------FEDPLAFDGLSLARHLD------------------EDSLPSSDEELL-------------GVGVGAALQDALYPLSPRD----------------ARFFRRLERPA-----------------KDSEG---------------------------SS--------DSDADELAAPYS-QGLDN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AUU5-1", "uniprot_id": "A0A8M3AUU5_DANRE", "id": "A0A8M3AUU5-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------MSSPSSSPEREGGMAGSVQLEDLNSPAGLEIDPPFIGSPVL-------------------------------------------------SPDSSSHDAALSAPAASP-ADSENLSPDELELLAKLEEQNRLLEADSKSMRSMSG------------------------------------------------------------SRRNSGSSLVSSSSASSNLSQLEEDT------WILWGRIVNEWDEWRRKKDKLLKELIRKGIPHHFRAIVWQ----------------LLCNATDMPVKNQYSELLKMSSPCEKLIRRDIARTYPEHDFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEHLLQEQLP--------ELNVHFRSQSFHTSMYASSWFLTLFLTFLPLPIATR-----------IFDIFMYEGLEIIFRVGIAILQYNQTDLIQLDMEGMSQHFQKVIPHQFDSCPDKLILRAYQVKYNPKRMKKLEKEYTTIKN------------------KEMEEQIEIKRLRTENRLLKQRIETLEKESAALADRLIQGQVTRAQ------EAEENYVIKRELAVVRQQCHTASESLEKAQDTIR------------------------------------------------------------------------------------------------------------ELQQH----KYTEEFVSGLQTQLEQSRLQEAELLGALKEM-----QDKVLDLEKRNSSLPD---------EINVAQLQEELKLVKLREQETLRSFREMQEAVTDLNHCWQHHTS---RGGGGGGGGHWKESPKKNAMN-------------ELQDKLMSLRLREAQGQAELKEVKLKNLQLE-SQNQINGKLLGRHEQE--STSLQERLQNALSHNKTLQSQLNEMKRKQAESDCKSKEEVMAVRLREADSMAAMAEL--------RQKIADLEIQKEEGL--IQGQLNH-SDSRQYITELRQQIAELKSEIRQLRGQPSKFQNNGSGVYQDLCLESPASAEGDYLSSDEDPLQSLPVSSLYPNHSSPRLDSQGSTDSDDPAGFRYGPPPSPVQWLPVNSRDIADIHSLSSRDGALDCPIVSPKYCSLCGKVFSSLSRLESHVFRAHGGHHGRALVFRDSKDP----VMPCRIKERTFECKECGKVFKRSSTLSTHLLIHSDTRPYPCLYCGKRFHQKSDMKKHTFIHTGEKPHVCKVCGKAFSQSSNLITHSRKHYRPYS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYY9-1", "uniprot_id": "EVI5_DROME", "id": "Q9VYY9-1", "name": "Ecotropic viral integration site 5 ortholog", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MTLTTT-------------------------------------------------TTASSAESQAKMDVKGGALPGEENLPTSEMDLLAKLEAANKLIESDAKSLNSLHSTH----------------------------------------------------------SRKNSDTSQISLTSSGN--SVAEEDI------WTTWATILNDWEGALKRKNPCVSELVRRGIPHHFRAIVWQ----------------QLSGASDG-DKKQYAEYIKATSACEKVIRRDIARTYPEVEFFKEKDGPGQEALFNVIKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVQIMQQHRMRHMFKPSMSELGLCMYQLENLVQEQIP--------DMHIHFQQQGFQTTMYASSWFLTLYTTTLNVNLSCR-----------IMDVFLSEGMEFIFKVALALLLTGKDTLLCLDMEAMLKFFQKELPGRVEADVEGFFNLAYSIKLNTKRMKKMEKEYQDLKK------------------KEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAE------EEETSYAIQTELMQLRRSYLEVSHQLENANEEVRGLSLRL------------------------------------------------------------------------------------QENNVSIDSNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNL-----KAKVEELEEDKKTLRET------TPDNSVAHLQDELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQRSESERTTNAVDSTPKKLLTNFFDSSKSSEHT-QKLEEELMTTRIREMETLTELKELRLKVMELE-TQVQVSTNQLRRQDEE--HKKLKEELEMAVTREKDMSNKAREQQHRYSDLESRMKDELMNVKIKFTEQSQTVAEL--------KQEISRLETKNSEML--AEGELRANLDDSDKVRDLQDRLADMKAELTALKSRGK--------------------FPGAKLRSSSIQ-------------------SIESTEIDFND---------------LNMVRRG------------------------------STELST--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q86TI0-1", "uniprot_id": "TBCD1_HUMAN", "id": "Q86TI0-1", "name": "TBC1 domain family member 1", "aln": "--------------------------------------------MEPITFTARKHLLSNEVSVDFGLQLVGSLPVHSLTTMPMLPWVVAEVRRLSRQSTRK---EPVTKQVRLCVSPSGLRCEPEPGR-------SQQWDPLIYSSIFECKPQRVHKLIHNSHDPSYFACLIKEDAVHRQS--ICYVFKADDQTKVPEIISSIRQAGKIARQEELHCPSEFDDTFS--KKFEVLFCGRVTVAHKKAPPALIDECIEKFNHVSGSRG------------------SESPRPNPPH---------------------AAPTGSQEPVRRPMRKSFSQPGLRSLAFR--KELQD-----GGLRSSGFFSSFEESDIENHLISGHNIVQPTDIEENRTML----------------FTIGQSEVYLISPDTKKIALEKNFKEISFCSQGIRHVDHFGFICRESSGGG--GFHFVCYVFQCTNEALVDEIMMTLKQAFTVAAVQQTAKAPAQLCEGCPLQSLHKLCERIEGMNSSKTKLELQKHLTTLTNQ---EQATIFEEVQKLRPRNEQRENELIISFLRCLYEEKQ-----------KEHIHIGEMKQTSQMAAENIGSELPPSATRFRLDMLKNKAKRSLTESLESILSRG-NKARGLQEHSISVDLDSSLSSTLSNTSKE--------------PSVCEKEALPISESSFKLLGSSEDLSSDSESHLPEEPAPLSPQQAFRRRANTLSHFPIECQEPPQPARGSPGVSQRKLMRYHSVSTETPHER-----------------------------------------------------------------------------------------------KDFESKANHLGDSGGTPVKTRRHSWRQQIFLRVATPQKACDSSSRYE-DYSELGELPPRSPLEPVCED--------GPFGPPPEEKKRTSRELRELWQKAILQQILLLRMEKENQKLQASEN--DLLNKRLKLDYEEITPCLKEVTTVWEKMLSTP-GRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQFHLKHQFPSKQQPK--DVPYKELLKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSLYAAPWFLTMFASQFPLG------------FVARVFDMIFLQGTEVIFKVALSLLGSHKPLILQHENLETIVDFIKSTLPNLG---------LVQMEKTINQVFEMDIAKQLQAYEVEYHVLQEELIDS----SPLS-DNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKLLSSESKLKQAMLTLELERSALLQTVEELRRRSAEPSDREPECTQPEPTGD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZMX5-1", "uniprot_id": "A0A8I5ZMX5_RAT", "id": "A0A8I5ZMX5-1", "name": "TBC1 domain family member 1", "aln": "--------------------------------------------MEAITFTARKHPFPNEVSVDFGLQLVGSLPVHSLTTMPMLPWVVAEVRRLSGQCSKK---EPGMKQVRLWVSPSGLRCEPDLRK-------SQPWDPLICSSIFECKPQRVHKLIHNSQDPSYFACLIKEDAAHQQS--LCYVFKADDQTKVPEIISSIRQAGKIARQEELRCPSEFDDTFA--KKFEVLFCGRVTVAHKKAPPALIDECIEKFNHVSCGRR------------------IDWDAPTGQP---------------------SAPG------ARPMRKSFSQPGLRSLAFR--KEFQD-----ASLRSS-TFSSFDN-DIENHLIGGHNVVQPTDMEENRTML----------------FTIGQSEVYLISPDTKKIALEKNFKEISFCSQGIRHVDHFGFICRECSGGGGAGFHFVCYVFQCTNEALVDEIMMTLKQAFTVAAVQQTAKAPAQLCEGCPLQGLHKLCERIEGMNSSKTKLELQKHLTTLTNQ---EQAMIFEEVQKLRPRNEQRENELIISFLRCLYEEKQ-----------KEHSHTGEPKQTLQVAAENIGSELPPSASRFRLDSLKNRAKRSLTESLESILSRG-NKARGLQDHSASVDLDSSTSSTLSNTSKE--------------LSMGDKEALPISESSFKLLGSSDDLSSDSESHIAEESALLSPQQAFRRRANTLSHFPVECPAPPEPAQTSPGVSQRKLMRYHSVSTETPHERNVDHLPGGESRCCPGQPSDPPPLPPRLNPSASSPNFFKYLKHNSSGEQSGNAVPKSVSYRNALRKKLHSSSSVPNFLKFLAPVDENNTCDFKNTNRDFESKANHLGDTDGTPVKARRHSWRQQIFLRVATPQKACDSPSRYE-DYSELGELPPRSPLEPVCED--------GPFGPVQEEKKKTSRELRELWKKAILQQILLLRMEKENQKLQASEN--DLLNKRLKLDYEEITPCLKEVTTVWEKMLSTP-GRSKIKFDMEKVHSAVGQGVPRHHRGEIWKFLAEQFHLKHPFPSKQQPK--DVPYKELLKKLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEYEIGPSLYAAPWFLTVFASQFPLG------------FVARVFDMIFLQGSEVIFKVALSLLGSHKPLILQHENLETIVDFIKNTLPNLG---------LVQMEKTISQVFEMDIAKQLQAYEVEYHVLQEELIDS----SPLS-DNQRMDKLEKTNSSLRKQNLDLLEQLQVANARIQSLEVTVEKLLTSESKLKQAVLTLEMERSALLQMVEELRRQMAQPSTAEPDCTRLEPTGD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60343-1", "uniprot_id": "TBCD4_HUMAN", "id": "O60343-1", "name": "TBC1 domain family member 4", "aln": "-----------------------------MEPPSCIQDEPFPHPLEPEPGVSAQPGPGKPSDKRFRLWYVGGSCLDHRTTLPMLPWLMAEIRRRSQKPEAGGCGAPAAREVILVLSAPFLRCVPAPGAGASGGTSPSATQPNPAVFIFEHKAQHISRFIHNSHDLTYFAYLIKAQPDDPESQMACHVFRATDPSQVPDVISSIRQLSKAAMKEDAKPSKDNEDAFYNSQKFEVLYCGKVTVTHKKAPSSLIDDCMEKFSLHEQQRLKIQGEQRG-PDPGEDLADLEVVVPGSPGDCLPEEADG-------TDTHLGLPAGASQPALTSSRVCFPERILEDSGFDEQQEFRSRCSSVTG-VQRRVHEGSQKSQPRRRHASAPSHVQPSDSEKNRTML----------------FQVGRFEINLISPDTKSVVLEKNFKDISSCSQGIKHVDHFGFICRESPEPG--LSQYICYVFQCASESLVDEVMLTLKQAFSTAAALQSAKTQIKLCEACPMHSLHKLCERIEGLYPPRAKLVIQRHLSSLTDN---EQADIFERVQKMKPVSDQEENELVILHLRQLCEAKQ-----------KTHVHIGEGP---STISNSTIPENATSSGRFKLDILKNKAKRSLTSSLENIFSRGANRMRGRLGSVDSFERSNSLASEKDYSPGD--------------SPPGTPPASPPS-SAWQTFPEED---SDS------------PQ--FRRRAHTFSHPPSSTKRKLNLQDGRAQGVRSPLLRQSSSEQCSNLSSVRRMYKESNSSSSLPSLHTSFSAPSFTAPSFLKSFY------------------------------QNSGRLSPQYENEIRQDTASESSDGEGRKRTSSTCSNESLSVGGTSVTPRRISWRQRIFLRVASPMNKSPSAMQQQ-DGLDRNELLPLSPLSPTMEEEPLVVFLSGEDDPEKIEERKKSKELRSLWRKAIHQQILLLRMEKENQKLEASRD--ELQSRKVKLDYEEVGACQKEVLITWDKKLLN--CRAKIRCDMEDIHTLLKEGVPKSRRGEIWQFLALQYRLRHRLPNKQQPP--DISYKELLKQLTAQQHAILVDLGRTFPTHPYFSVQLGPGQLSLFNLLKAYSLLDKEVGYCQGISFVAGVLLLHMSEEQAFEMLKFLMYDLGFRKQYRPDMMSLQIQMYQLSRLLHDYHRDLYNHLEENEISPSLYAAPWFLTLFASQFSLG------------FVARVFDIIFLQGTEVIFKVALSLLSSQETLIMECESFENIVEFLKNTLPDMN---------TSEMEKIITQVFEMDISKQLHAYEVEYHVLQDELQES----SYSCEDSETLEKLERANSQLKRQNMDLLEKLQVAHTKIQALESNLENLLTRETKMKSLIRTLEQEKMAYQKTVEQLRKLLPADALVNCDLLLRDLNCNPNNKAKIGNKP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3Z881-1", "uniprot_id": "D3Z881_RAT", "id": "D3Z881-1", "name": "TBC1 domain family member 4", "aln": "-----------------------------MESPSCIQDEPFPHPLEPEPIALAQPGATKPGDKRFRLWYVGGSCLDRRTTLPMLPWLMAEIRRRSLKPEAGGCGAPAAREVLLVLSAPFLRCVPAPGVGVGGGAGSGAVQPNTGVFIFEHKAQHISRFIHNSHDLTYFAYLIKAQPDDPESQMACHVFRATDPNQVPDVISSIRQLSKAAMKEDAKPSKDNEDAFYNSQKFEVLYCGRVIVTHKKAPSSLIDDCKDKFSLHEQQRLKLQGERGGDPGDGDEMGVLEAESPVSPDDGLPEKPDGLVNCPRALPSLASLPALASQPALASSRVCFPERILEDCGFDEQQEFRSRCSSVTGVMQKKVHENNQKTQPRRRHASAPSHVQPSDSEKNRTML----------------FQVGRFEINLISPDTKSVVLEKNFKDISSCSQGIKHVDHFGFICRESLEPG--LSQYICYVFQCANESLVDEVMLTLKQAFSTAAALQSAKTQIKLCEACPMHSLHKLCERIEGLYPPRAKLVIQRHLSSLTDN---EQADIFERVQKMKPISDQEENELVILHLRQLCEAKQ-----------KTHVHIGEGQ---AIISNSTIPENSTSGGRFKLDVLKNKAKRSLTSSLENIFSRGANRMRGRLGSVDSFERSNSLASEKDFSPGG--------------SPPGTPPASPLS-SAWHTFPEED---SDS------------PQ--FRRRAHTFSHPPSSSRRKLNLQDGKAHGLRSPLLRQNSSEQCS---------------------------------------------------------------------------------------------DGEGRKRTSSTCSNESLSAGGTPVTPRRISWRQRIFLRVASPVNKSPSAMQQQKDGLDRTELLPLSPLSPTMEEEPLVIFLSGDEDTEKVEEKKKSKEIKSLWKKAIHQQILLLRMEKENQKLEARRD--ELQSRKVKLDYEEVGTCQKEVLIAWDKKLLN--CRTKIRCDMEDIHTSLKEGVPKSRRGEIWQFLALQYRLRHRLPNKHQPP--DTSYKELLKQLTAQQHAILVDLGRTFPTQPYFSVQLGAGQLSLFNLLKAYSLLDKEVGYCQGISFVAGVLLLHMSEEQAFEMLKFLMYDLGFRKQYRPDMMSLQIQMYQLSRLLHDYHRDLYNHLEENEISPSLYAAPWFLTLFASQFPLG------------FVARVFDIIFLQGTEVIFKVALSLLSSQEALVMECENFENIVEFLKSTLPDMN---------TTEMEKIITQVFEMDISKQLHAYEVEYHVLQDELLES----SYACEDNESLEKLERANNQLKRQNMDLLEKLQVAHAKIQALESNLETLLTRETKMKALIRTLEQDKMAYQKTVEQIRKLLPADALANCELLLKDLSYPTNDKAKAGNKP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E1JJ52-1", "uniprot_id": "E1JJ52_DROME", "id": "E1JJ52-1", "name": "", "aln": "MKTRLVSLTFRGSASVDPRYSASMLPWTINDIRSTESYTKLSVGIENGILESYNSDFELQFSHPLKHIVGMCRIIHKPQAKSIGNGFLQLKSSAGQTSSSSAVASSMGGAASSSLTGNGLRHTLTASTSYGSLSSSAACAYQLQLQQSAEASAEQPQNFMEFQGPITGLVYLLKDPKDPLLHIYLFECEAVEEMAELMHQMRDPAHTLGGSVGSIPQTLIGGGGGSHGNSNGALNGIHATPATNLKMSEAMRNAQHDTSPNPVSSKMKASKSYTHG-----------------------------------------------LSSSSGTVNIPTSTSAQSNLSLLADISPNHTHFFEVMYVGKIRVSQKRVPNTFIDDALPKFKAYDAQRLRLLQNRKMSLSSEGGVGIEAKPSSSLKSHDLKEEDEEEQEQHKGHDDSQDSQAKPLVQLQLTGAEEGAAPRPLEDNKENKSPEKRPLLRGQSQIELGHKEHSDGSQPLAANSQLEAPNVIVNKQPTPPRDQGVGTGTASASAGPSQLHPNYAMDNIPKQRDRSASQGCIPPYVEQNRTMVFLVGRCDLRLISPDRKQVLLYKDFKDVASCVHGQKSLDHFGIICRELNNDGYIGYVFKCQSEHVCDDIVAAIAQAFDTCAEQKKKQDTQIFSCEHCPMLWYHKLCTDVEGLSEKKTQALILRRIETLSDDEQEIVWAKFCGSEKTNSPVAEQNQFLMMLLRAHCESRQQRHVHDTAENRSEFLNQYLGGSTIFMKAKRSLTNSFDNLLKRKPSKDDIAVPSHN--------------------------------------------------------------------LRDIREGSAEPLGTQSPPEGFRSRSNTVGASPSSKPTAEQLKSPMMDIFIKVGNSPKEAETHQGSWRQAILNSVVTPSKGLDSEVPTEFLS-----PMRKPAKRGKRDAAELRELWRTAIRQTIMLNRMETENAMLQARQN--ENELKRIKLDYEEIVPCDKQLIERWEQIIERNSTQIGNKKDPKVLGHAIRTGVPRSKRGDVWTFLAEQHSMNTAPVDTKRFPNFNTPYHMLLKHLTEHQHAIFIDLGRTFPNHQFYKDPLGLGQLSLFNLLKAYSILDPELGYCQGLGFICGVLLLHCDEANSFQLLKHLMFRRNMRTKYLPDMKKFQLQLYQLSRLVKDHLPDLYVWLDQNDVSPTLYAAPWILTVFSSQFPLG------------FVARVFDLLFLESSDVIFKFAIALLSVHKQQLLAKDNFEEIMDYLKTVVPKMEH---------TCMEQIMKLVFSMDIGKQLAEYKVEYNVLQEEITTTNHHLEMLNREKTQNQHLEQQLQFAQSSIAQLETTRSSQQAQITTLQSQVQSLELTIQTLGRYVGQLVEHNPDLELPNEVRRMLQQLDDLDRQRRKPIFTERKIGKSVSVNSHLGFPLKVLEELTERDELGSPQKQKKEKTPFFEQLRQQQQQHRLNGGGQSSNVGESGSPTPPSRPNRLLDNASARTVMQVKLDELKLPEHVDKFVANIKSPLEVDSGVGTPLSPPSTASNSSGGSIFSRMGYRTTPPALSPLAQRQSYGVAITTAPCPQHMEEVAPATTMAVMPQEDVEEPQPMHPLSMVGGDVNVRFKGTTQLKSIRPVHHMRAIPLGGVQHPSSTEPAVRVAPVPVELAPPAATATTGRS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04322-1", "uniprot_id": "GYL1_YEAST", "id": "Q04322-1", "name": "Probable GTPase-activating protein GYL1", "aln": "-----------------------------------------------------------------------------------------------------MNSNEDIHEERIEVPRTPHQTQPEKDSDRIALRDEISVPEGDEKAYSDEKVEMATTNAS-------------------------------------------------SNFGSNESAKDGESIGAFSNPHEALMQSKLREESQSKTILPSDDLSQQLETEESK-------------------------------------------------------------VEEALKRITSPPLPPRADCIEESAS-----------ALKSSLPPVLAGNKNDQAPLDRPQLPPRQVVNAET----------------LHLKAPHGNATPSKSPTSAVGNSSSSTPPTLPPRRIEDPLDLAAQKHFLASTFKRNMLFYKSEDNSIKCDLDKNILNLKEDSKKINNNEIPEEVSSFWLKVIGDYQNILINDIETLHFQLSRGIPAAYR----------LVVWQLVSYAKSKSFDPIYETYLTEMAPFDVQEF-----------------ENQLKMMDEVPSEYVKRISNVLKAYLLFDPECEFSTDIAYIINMILDVCEEEANAFGLLVRLMKVYGLRLLFLPS-----------------------ASEIDILCYKFDRLVEEFYPEIHN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HMVEKGVRSSMFLPGFFTTLFQKKLPTEIQPR-----IGDMVFLEGIDSIMRIL--------ATLLSNSRDHLLKMGFDDMLELLKSGLLDAYIKQNDGTRGDTLLS-------------NECMDKLLQDS------------MMKVAITPKTMKKYSSEYEEIHRLDNEKEVQYKSITEKNLHLQKHVRK-----LENDYTSLNREHVTIANELVKNRLNIESVLNENNGYKLQILDLKKKLDSEKKKQ------------VLGVYVPNDLKKDLEETMKKNTQVMDENLKLQDRISELERLIEEIKTANK----------------NGTLFEYSNSKNNPLG-------------------AGWSGFKKVFK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : . . . . : . . . . : . . . . . . . : . ", "identical_positions": 0, "similar_positions": 23, "identity": "0.0%" }, { "cls_id": "homologset.agr.SGD:S000004806", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJY1-1", "uniprot_id": "D3ZJY1_RAT", "id": "D3ZJY1-1", "name": "Large ribosomal subunit protein bL28m", "aln": "----MPLHRYPVHLWQK-LRLQQGICARLPSHFLRSLEEE--RTPTPVHYKPHGAKFKINPKNGQRERVEDVPIPVHYPPESQQELWGGEGLILGYRYANNDKLSNRVKKVWKPQLFTRELYSEILDKKFTVTVTMRTLDLIDEAYGFDFYILKTPEEDLCSK--FGMDLKRGMLLRLARQDPQLHPDNPERRAAIYDKYRNFVIP--EAEAEWVGLTLEEALE--KQRLLEEKDPVPLFKVYVEELVQRLQEQALSRPAVVQKRAGDHV-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D1B9-1", "uniprot_id": "RM28_MOUSE", "id": "Q9D1B9-1", "name": "Large ribosomal subunit protein bL28m", "aln": "----MPLHRYPVHLWQK-LRLRQGICARLPAHFLRSLEEE--RTPTPVHYKPHGTKFKINPKNGQRERVEDVPIPVHYPPESQQGLWGGEGLILGYRYANNDKLSKRVKKVWKPQLFTRELYSEILDKKFTVTVTMRTLDLIDEAYGFDFYILKTPKEDLGSK--FGMDLKRGMLLRLARQDPHLHPENPERRAAIYDKYRSFVIP--EAEAEWVGLTLEEALE--KQRLLEEKDPVPLFKVYVEELVQRLQEQVLSRPAVVQKRAGDHA-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13084-1", "uniprot_id": "RM28_HUMAN", "id": "Q13084-1", "name": "Large ribosomal subunit protein bL28m", "aln": "----MPLHKYPVWLWKR-LQLREGICSRLPGHYLRSLEEE--RTPTPVHYRPHGAKFKINPKNGQRERVEDVPIPIYFPPESQRGLWGGEGWILGQIYANNDKLSKRLKKVWKPQLFEREFYSEILDKKFTVTVTMRTLDLIDEAYGLDFYILKTPKEDLCSK--FGMDLKRGMLLRLARQDPQLHPEDPERRAAIYDKYKEFAIP--EEEAEWVGLTLEEAIE--KQRLLEEKDPVPLFKIYVAELIQQLQQQALSEPAVVQKRASGQ--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VMX0-1", "uniprot_id": "RM28_DROME", "id": "Q9VMX0-1", "name": "Large ribosomal subunit protein bL28m", "aln": "MAHATPQGVKLLNGWKRPGRFDKGLGAQLPEAYRKFWREWKLTTPAAVHYIPKEQQWERDEVTHAIKPVQNIPLPLIDTPESHRGIWGGEAVIKG--FQKREQTKRRVPHFWVPNLRRSVVHSHVLDCYMSVVVTERTLEQIHECHGFDHYLLKNRACDLRSA--LALKLKREVLQALQNGVPALADE-PERQQEVLKEYRRYLEPYTPEEIDWYGHTYLEAIRKLQKQLREAEKVVPHKLEFRGKLIEQLRQAGISEAGKLEKPDALAAESSVEHKDSDIEALTKLESSPSSSWLSKINPFGKKET", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36525-1", "uniprot_id": "RM24_YEAST", "id": "P36525-1", "name": "Large ribosomal subunit protein bL28m", "aln": "-----------MQKIFRPFQLTRGFTSSVKNFRQWRLIETR-KIAKQPNYQVGDAKPLHMPKERKKFPDYKYGESNIFK-QSNKGLYGGSFVQFG---NNISESKAKTRKKWLPNVVKKGLWSETLNRKISIKMTAKVLKTISKEGGIDNYLTKEKSARIKELGPTGWKLRYRVLKRKDEIENPPHKDAPIIEMAGGKKAKIYYDEIVNGSPRKISVGRRRLMSFLYPLEKLEYRSVGKDLNYKKFVELFADVPVKDILARLEDHKFDLSTITV---------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: .*: : : * . :* : . . :*:: ::**. * : .: . : : * *:: . *. *: ::: :* :.*. * : *:* *: * : . . .*: :* . : * . .: : : . . . : * : : . . ::. ", "identical_positions": 22, "similar_positions": 64, "identity": "7.17%" }, { "cls_id": "homologset.agr.SGD:S000004807", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LZ43-1", "uniprot_id": "A0ABK0LZ43_RAT", "id": "A0ABK0LZ43-1", "name": "60S ribosomal protein L36", "aln": "MALRYPMAVGLNKGHKVT------------------------KNVSKPRHSRRR-GRLTKHTKFVRDMIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNVLAAMRKAAAKKD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZZ95-1", "uniprot_id": "D3ZZ95_RAT", "id": "D3ZZ95-1", "name": "60S ribosomal protein L36", "aln": "MALRYPMAVGLNKGHKVT------------------------KNVSKPRHSRRRRGRLTKHTKFVRDMIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNVLAAMRKAAAKKD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47964-1", "uniprot_id": "RL36_MOUSE", "id": "P47964-1", "name": "Large ribosomal subunit protein eL36", "aln": "MALRYPMAVGLNKGHKVT------------------------KNVSKPRHSRRR-GRLTKHTKFVRDMIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNVLAAMRKAAAKKD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M706-1", "uniprot_id": "F1M706_RAT", "id": "F1M706-1", "name": "60S ribosomal protein L36", "aln": "MALRYPMAMGLNKGHKVT------------------------KNVSKPRHSRRR-GRLTKHTKFVRDMIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKKVG-THIR------AKRKREELSNVLAAMRKAAAKKD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A1Q0-1", "uniprot_id": "D4A1Q0_RAT", "id": "D4A1Q0-1", "name": "Large ribosomal subunit protein eL36", "aln": "MALRYPMAVGLNKGHKVT------------------------KNVSKPRHSRRR-GRLTKHTKFVRDMIREVCG--------FAPYQRRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNVLAAMRKAAAKD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0RCN1-1", "uniprot_id": "M0RCN1_RAT", "id": "M0RCN1-1", "name": "Large ribosomal subunit protein eL36", "aln": "MALRYPMAVGLNKSHKVT------------------------KNVSKTRHSRRR-GRLTKHTKFVRDMIPEVCG--------FAPYVRRTMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNVLAAMRKD--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6Q415-1", "uniprot_id": "RL36_DANRE", "id": "Q6Q415-1", "name": "Large ribosomal subunit protein eL36", "aln": "MVVRYPMAVGLNKGHKVT------------------------KNVSKPKHSRRR-GRLTKHAKFARDLIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNTLAAMRKAAAKKE---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P49630-1", "uniprot_id": "RL36_DROME", "id": "P49630-1", "name": "Large ribosomal subunit protein eL36", "aln": "MAVRYELAIGLNKGHKTSKIRN--------------VKYTGDKKVKGLRGSRLK-NIQTRHTKFMRDLVREVVG--------HAPYEKRTMELLKVSKDKRALKFLKRRLG-THIR------AKRKREELSNILTQLRKAQTHAK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05745-1", "uniprot_id": "RL36A_YEAST", "id": "P05745-1", "name": "Large ribosomal subunit protein eL36A", "aln": "MTVKTGIAIGLNKGKKVT------------------------SMTPAPKISYKK-GAASNRTKFVRSLVREIAG--------LSPYERRLIDLIRNSGEKRARKVAKKRLG-SFTR------AKAKVEEMNNIIAASRRH--------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "C0HME6-1", "uniprot_id": "ALT36_HUMAN", "id": "C0HME6-1", "name": "RPL36 alternative reading frame protein", "aln": "MASEAEGAGTRGSGPRELSRYSPPPLLPVAVRSHGPTLPYGRGPQQGPQSDQEREQAQAQPTPRASDQTHQVRAGHDSGGVWLCPVRAARHGVTEGLQGQTGPQIYQEKGGDAHPRQEEAGGAEQRTGRHEESCCQERLSPSPALSLK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . * ... : : . : :. : . :: . .* : . : . :. :.: * :. * *: : . .: * ", "identical_positions": 7, "similar_positions": 33, "identity": "4.73%" }, { "cls_id": "homologset.agr.SGD:S000004810", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96AJ9-2", "uniprot_id": "VTI1A_HUMAN", "id": "Q96AJ9-2", "name": "Vesicle transport through interaction with t-SNAREs homolog 1A", "aln": "------MSSDFEGYEQDFAVLTAEITSKIARVPRLPPD-EKKQMVANVEKQLEEAKELLEQMDLEVREIP--PQSRGMYSNRMRSYKQEMGKLETDFKRSRIAYSDEVRNELLGDDGNSSEN-------QRAHLLDNTERLERSSRRLEAGYQIAVETEQIGQEMLENLSHDREKIQRARERLRETDANLGKSSRILTGMLRRIIQNRILLVILGIIVVITILMAITFSVRRH-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JI51-1", "uniprot_id": "VTI1A_RAT", "id": "Q9JI51-1", "name": "Vesicle transport through interaction with t-SNAREs homolog 1A", "aln": "------MSADFEGYEQDFAVLTAEITSKISRVPRLPPD-EKKQMVANVEKQLEEARELLEQMDLEVREIP--PQSRGMYSNRMRSYKQEMGKLETDFKRSRIAYSDEVRNELLGDAGNSSENQLIKLREERAHLLDNTERLERSSRRLEAGYQIAVETEQIGQEMLENLSHDRERIQRARERLRETDANLGKSSRILTGMLRRIIQNRILLVILGIIVVITILTAITFFVRGH-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89116-1", "uniprot_id": "VTI1A_MOUSE", "id": "O89116-1", "name": "Vesicle transport through interaction with t-SNAREs homolog 1A", "aln": "------MSSDFEGYEQDFAVLTAEITSKIARVPRLPPD-EKKQMVANVEKQLEEARELLEQMDLEVREIP--PQSRGMYSNRMRSYKQEMGKLETDFKRSRIAYSDEVRNELLGDAGNSSEN-------QRAHLLDNTERLERSSRRLEAGYQIAVETEQIGQEMLENLSHDREKIQRARDRLRDADANLGKSSRILTGMLRRIIQNRILLVILGIIVVIAILTAIAFFVKGH-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9W0N6-1", "uniprot_id": "Q9W0N6_DROME", "id": "Q9W0N6-1", "name": "", "aln": "-------MSLLEQYEQQYATLIAEITAHIGRLQQQNNNSERHDLCSKIDSSLPEAQELLEQMGLEVRELN--PGLRSSFNGKLQVAQAELKRLQAEYRLTKDKQRSQANTFTTLDLGDSYEDVSIS-TDQRQRLLDNSERIERTGNRLTEGYRVALETEQLGAQVLNDLHHQRETLQGARARLRETNAELGRASRTLNTMMLRALREKVVLYGVGVCFVVAVGVSLYLTFAPSSSSTASS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P58200-1", "uniprot_id": "VTI1B_RAT", "id": "P58200-1", "name": "Vesicle transport through interaction with t-SNAREs homolog 1B", "aln": "MATSAASSEHFEKLHEIFRGLLEDLQGVPERLLGTAGTEEKKKLVRDFDEKQQEANETLAEMEEELRYAP--LTFRNSMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDLKFGTYTLENEHLNRLQSQRALLLQGTESLNRATQSIERSHRIAAETDQIGSEIIEELGEQRDQLERTKSRLVNTNENLSKSRKILRSMSRKVITNKLLLSVIIVLELAILVGLVYYKFFRHH------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88384-1", "uniprot_id": "VTI1B_MOUSE", "id": "O88384-1", "name": "Vesicle transport through interaction with t-SNAREs homolog 1B", "aln": "MAASAASSEHFEKLHEIFRGLLEDLQGVPERLLGTAGTEEKKKLVRDFDENQQEANETLAEMEEELRYAP--LTFRNPMMSKLRNYRKDLAKLHREVRSTPLTAAPGGRGDLKYGTYTLENEHLNRLQSQRALLLQGTESLNRATQSIERSHRIATETDQIGTEIIEELGEQRDQLERTKSRLVNTNENLSKSRKILRSMSRKVITNKLLLSVIILLELAILVGLVYYKFFRHH------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04338-1", "uniprot_id": "VTI1_YEAST", "id": "Q04338-1", "name": "t-SNARE VTI1", "aln": "------MSSLLISYESDFKTTLEQAKASLAEAPSQPLS-QRNTTLKHVEQQQDELFDLLDQMDVEVNNSIGDASERATYKAKLREWKKTIQSDIKRPLQSLVDSGDRDRLFGDLNASNIDDD-------QRQQLLSNHAILQKSGDRLKDASRIANETEGIGSQIMMDLRSQRETLENARQTLFQADSYVDKSIKTLKTMTRRLVANKFISYAIIAVLILLILLVLFSKFK---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. : : . . ::: ..:.. * : * :* *:. * ::: : : : . . :: :* **.. :::: : . ::* **: :* ::: :* :*: :: :: * ::: :.:: : * * : : ::.: : : : : . ", "identical_positions": 17, "similar_positions": 71, "identity": "7.08%" }, { "cls_id": "homologset.agr.SGD:S000004814", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M0X7-1", "uniprot_id": "A0ABK0M0X7_RAT", "id": "A0ABK0M0X7-1", "name": "DNA repair protein complementing XP-A cells homolog", "aln": "----------------MPVSPRSQAIPVVPCAWHIYGAELSVLQPLNKPAPSPTPAPSRTAPDPVFYMRRACFPAQSRLTP-----------AEPRTLELTRLGVTSIKAA-----------PKVIDTKGGFILEE----------EEEEKHKIGD-------------------VVHEPGPVMEFDYTICEECG-KEFMDSYLMNHFDLPTCDSCRDAD-DKHKLITKTEAKQEYLLKDCDLEKREPALRFIVKKNPRHSQWGDMKLYLKLQVVKRALEVWGSQEALEDAKEVRQENREKMKQKKFDKKVKELRRAVRSSVWK-----RET-TAHQHEYG-PEEH-LEEDMY---RKTCTLCGHELTYEKM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64267-1", "uniprot_id": "XPA_MOUSE", "id": "Q64267-1", "name": "DNA repair protein complementing XP-A cells homolog", "aln": "----------------MATAEEKQTSP----------------EPVAADEPAQLPAAVRASVE--RKRQRALMLRQARLA------------ARPYPAAAATGGVASVKAA-----------PKMIDTKGGFILEE----------EEE-KHEIGN-------------------IVHEPGPVMEFDYTICEECG-KEFMDSYLMNHFDLPTCDSCRDAD-DKHKLITKTEAKQEYLLKDCDLEKREPALRFLVKKNPRHSQWGDMKLYLKLQVVKRALEVWGSQEALEDAKEVRQENREKMKQKKFDKKVKELRRAIRSSVWK-----RET-TTHQHKYG-PEEN-LEDDMY---RKTCTLCGHELTYEKM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23025-1", "uniprot_id": "XPA_HUMAN", "id": "P23025-1", "name": "DNA repair protein complementing XP-A cells", "aln": "----------------MAAADG--ALP----------------EAAALEQPAELPASVRASIE--RKRQRALMLRQARLAAR----------PYSATAAAATGGMANVKAA-----------PKIIDTGGGFILEE----------EEEEEQKIGK-------------------VVHQPGPVMEFDYVICEECG-KEFMDSYLMNHFDLPTCDNCRDAD-DKHKLITKTEAKQEYLLKDCDLEKREPPLKFIVKKNPHHSQWGDMKLYLKLQIVKRSLEVWGSQEALEEAKEVRQENREKMKQKKFDKKVKELRRAVRSSVWK-----RET-IVHQHEYG-PEEN-LEDDMY---RKTCTMCGHELTYEKM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28518-1", "uniprot_id": "XPA_DROME", "id": "P28518-1", "name": "DNA repair protein complementing XP-A cells homolog", "aln": "---------------MSAEVSTNESAP-------------------PAEKKSKLTNAQKARIE--RNQAKAQKLREAKLVSHPFKELASNKEGGTHPEAALSQGSSVIKVQG----------TKYIDSGGGFLLEQPVMPTG---VGPAGLNKSGEEAP----------------PILDDAIAIPVQYEECLECG-DMFADSYLFNNFGHSVCDKCRDKD-ERYALITRTEAKAEYLLKDCDFDKREPKLRYISRKNPHNVRWGEMKLYLHLQIHQRALEVWGSEEELVRQHEAREDKREEGKARKYNKKMKQLRMEVRSSIYT-----KKTHEVHEHEFG-PDTYDEEEDTY---THTCITCPYSETYEKM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28519-1", "uniprot_id": "RAD14_YEAST", "id": "P28519-1", "name": "DNA repair protein RAD14", "aln": "MTPEQKAKLEANRKLAIERLRKRGILSSDQLNRIESRNEPLKTRPLAVTSGSNRDDNAAAAVHVPNHNGQPSALANTNTNTTSLYGSGVVDGSKRDASVLDKRPTDRIRPSIRKQDYIEYDFATMQNLNGGYINPKDKLPNSDFTDDQEFESEFGSKKQKTLQDWKKEQLERKMLYENAPPPEHISKAPKCIECHINIEMDPVLHDVFKLQVCKQCSKEHPEKYALLTKTECKEDYFLTDPELND-EDLFHRLEKPNPHSGTFARMQLFVRCEVEAFAFKKWGGEEGLDEEWQRREEGKAHRREKKYEKKIKEMRLKTRAQEYTNRLREKKHGKAHIHHFSDPVDGGIDEDGYQIQRRRCTDCGLETEEIDI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . :. ::. . :: .. : **:: : : *. . * ** . *. * : * .*..* . . ::: *:*:**.* :*:*.* :::. * :: : : **: :. *:*::: :: ::: **.:* * : *:: : . : :*::**:*::* *:. :. :: .* *.:. * ::* * : * * . .:", "identical_positions": 42, "similar_positions": 88, "identity": "11.29%" }, { "cls_id": "homologset.agr.SGD:S000004815", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R0C9-1", "uniprot_id": "SGMR1_RAT", "id": "Q9R0C9-1", "name": "Sigma non-opioid intracellular receptor 1", "aln": "MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLD---HELAFSRLIVELRRLHPGHVLPD-----EELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55242-1", "uniprot_id": "SGMR1_MOUSE", "id": "O55242-1", "name": "Sigma non-opioid intracellular receptor 1", "aln": "MPWAAGRRWAWITLILTIIAVLIQAAWLWLGTQNFVFSREEIAQLARQYAGLD---HELAFSRLIVELRRLHPGHVLPD-----EELQWVFVNAGGWMGAMCILHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWKEGTTKSEVFYPGETVVHGPGEATALEWGPNTWMVEYGRGVIPSTLFFALADTFFSTQDYLTLFYTLRAYARGLRLELTTYLFGQDS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99720-1", "uniprot_id": "SGMR1_HUMAN", "id": "Q99720-1", "name": "Sigma non-opioid intracellular receptor 1", "aln": "MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLD---HELAFSRLIVELRRLHPGHVLPD-----EELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZWG9-1", "uniprot_id": "SGMR1_DANRE", "id": "Q7ZWG9-1", "name": "Sigma non-opioid intracellular receptor 1", "aln": "--MSLIRTILKLVVVVGFLSLTVQFIRHWMANKQYVFTKEEVAKLAKQYAGQD---HEQAFSKVVVELRRRYPGHILPD-----EDLQWVFVNAGGWMGSMCLLHASLTEYVLLFGTAVDTGGHSGRYWAEISDTIISGTFRQWKEGTTKSETYYPGDTIVHSAGEATSVQWSSGTWMVEYGRGFIPSTLGFALADTMFSTQDFLTLFYTARVYVKGMILEASTFLTESGVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32352-1", "uniprot_id": "ERG2_YEAST", "id": "P32352-1", "name": "C-8 sterol isomerase ERG2", "aln": "------MKFFPLLLLIGVVGYIMNVLFTTWLPTNYMFDPKTLNEICNSVISKHNAAEGLSTEDLLQDVRDALASHYGDEYINRYVKEEWVFNNAGGAMGQMIILHASVSEYLILFGTAVGTEGHTGVHFADDYFTILHGTQIAALPYATEAEVYTPGMTHHLKKGYAKQYSMPGGSFALELAQGWIPCMLPFGFLDTFSSTLDLYTLYRTVYLTAR----DMGKNLLQNKKF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: . . : .::* : : ::... . . . : . :: ::* ..* : . :*** **** ** * :****::**::*****:.: **:* ::*: **: ** :*::*.: ** * * *. . .:: :* .:* **. * *.: **. ** * **: * .: : . * . ", "identical_positions": 54, "similar_positions": 66, "identity": "23.28%" }, { "cls_id": "homologset.agr.SGD:S000004816", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A4F267-1", "uniprot_id": "TM40L_RAT", "id": "A4F267-1", "name": "Mitochondrial import receptor subunit TOM40B", "aln": "MGNTLG-----------------------LAPMG-TLP-------------RWSHRREEP----------------LPNPGSFDELHRLC-KDVFPAQ--MEGVKLVVNKVLSS--HFQVAHTVHMSALGLPGYHLHTAYAGDWQLSPTEVFPTVVGDMDSSGSLNAQVLLLLAERLRAKAVFQTQQAKFLTWQFDGEYRGDDYTATLTLGNPDLIGE---SVIMVAHFLQSITHRLVLGGELVYHRRP---GEEGAILTLAGKYSAL--HWVATLNVGS-GGAHASYYHKANEQVQVGVEFEANTRLQ-----------------DTTFSFGYHLTLPQADMVFRGLVDSNWCVGAVLEKKMRPLPVTLALGAFLNHWRNRFHCGFSITVG---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CZR3-1", "uniprot_id": "TM40L_MOUSE", "id": "Q9CZR3-1", "name": "Mitochondrial import receptor subunit TOM40B", "aln": "MGNTLG-----------------------LAPMG-TLP-------------RRSHRREEP----------------LPNPGSFDELHRLC-KDVFPAQ--MEGVKLVVNKVLSS--HFQVAHTVHMSALGLPGYHLHTAYAGDWQLSPTEVFPTVVGDMDSSGSLNAQVLLLLAERLRAKAVFQTQQAKFLTWQFDGEYRGDDYTATLTLGNPDLIGE---SVIMVAHFLQSITHRLVLGGELVYHRRP---GEEGAILTLAGKYSAV--HWVATLNVGS-GGAHASYYHKANEQVQVGVEFEANTRLQ-----------------DTTFSFGYHLTLPQADMVFRGLVDSNWCVGAVLEKKMRPLPVTLALGAFLNHWRNRFHCGFSITVG---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969M1-1", "uniprot_id": "TM40L_HUMAN", "id": "Q969M1-1", "name": "Mitochondrial import receptor subunit TOM40B", "aln": "MGNTLG-----------------------LAPMG-TLP-------------RRSPRREEP----------------LPNPGSFDELHRLC-KDVFPAQ--MEGVKLVVNKVLSS--HFQVAHTIHMSALGLPGYHLHAAYAGDWQLSPTEVFPTVVGDMDSSGSLNAQVLLLLAERLRAKAVFQTQQAKFLTWQFDGEYRGDDYTATLTLGNPDLIGE---SVIMVAHFLQSLTHRLVLGGELVYHRRP---GEEGAILTLAGKYSAV--HWVATLNVGS-GGAHASYYHRANEQVQVGVEFEANTRLQ-----------------DTTFSFGYHLTLPQANMVFRGLVDSNWCVGAVLEKKMPPLPVTLALGAFLNHWRNRFHCGFSITVG---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QYA2-1", "uniprot_id": "TOM40_MOUSE", "id": "Q9QYA2-1", "name": "Mitochondrial import receptor subunit TOM40 homolog", "aln": "MGNVLAASSPPAGPPPPPTPSLVGLPPPPPSPPGFTLPPLGGGLGTGSSTGRGSERTPGAAASGAAAASEDGSCGCLPNPGTFEECHRKC-KELFPVQ--MEGVKLTVNKGLSN--RFQVTHTVALGTIGESNYHFGVTYVGTKQLSPTEAFPVLVGDMDNSGSLNAQVIHQLSPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTAAVTLGNPDVLVG---SGILVAHYLQSITPCLALGGELVYHRRP---GEEGTVMSLAGKYTLN--NWLATVTLGQ-AGMHATYYHKASDQLQVGVEFEASTRMQ-----------------DTSASFGYQLDLPKANFLFKGSVNSNWIVGATLEKKLPPLPLTLSLCAFLNHRKNKFLCGFGLTIG---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q75Q40-1", "uniprot_id": "TOM40_RAT", "id": "Q75Q40-1", "name": "Mitochondrial import receptor subunit TOM40 homolog", "aln": "MGNVLAASSPPAGPPPPPTPSLVGLPPPPPSPPGFTLPPLGGGLGTGSNAGRGSERTPGAAASGAAASSNDGNCGCLPNPGTFEECHRKC-KELFPVQ--MEGVKLTVNKGLSN--RFQVTHTVALGTIGESNYHFGVTYVGTKQLSPTEAFPVLVGDMDNSGSLNAQVIHQLSPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTAAVTLGNPDVLVG---SGILVAHYLQSITPCLALGGELVYHRRP---GEKGTVMSLAGKYTLN--NWLATVTLGQ-AGMHATYYHKASDQLQVGVEFEASTRMQ-----------------DTSASFGYQLDLPKANFLFKGSVNSNWIVGATLEKKLPPLPLTLSLCAFLNHRKNKFLCGFGLTIG---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O96008-1", "uniprot_id": "TOM40_HUMAN", "id": "O96008-1", "name": "Mitochondrial import receptor subunit TOM40 homolog", "aln": "MGNVLAASSPPAGPPPPPAPALVGLPPPPPSPPGFTLPPLGGSLGAGTSTSRSSERTPGAATASASGAAEDGACGCLPNPGTFEECHRKC-KELFPIQ--MEGVKLTVNKGLSN--HFQVNHTVALSTIGESNYHFGVTYVGTKQLSPTEAFPVLVGDMDNSGSLNAQVIHQLGPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTAAVTLGNPDVLVG---SGILVAHYLQSITPCLALGGELVYHRRP---GEEGTVMSLAGKYTLN--NWLATVTLGQ-AGMHATYYHKASDQLQVGVEFEASTRMQ-----------------DTSVSFGYQLDLPKANLLFKGSVDSNWIVGATLEKKLPPLPLTLALGAFLNHRKNKFQCGFGLTIG---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z1R1-1", "uniprot_id": "A0A8M6Z1R1_DANRE", "id": "A0A8M6Z1R1-1", "name": "", "aln": "MRRESSSSCWYTSFLTMGSVLAASSPNPPPASGGGTAP-AGAGLVTVPPGFTMPPVSGVPPSSGTQGQPGTDSESSLPNPGTFEECHRKC-KEVFPVQ--MEGVRLVVNKGLSN--HFQVSHTITLSTLGDSGYRFGSTYVGSKQTGPAESFPVMVGDMDNTGSLNAQVIHQLTNRVRSKIAIQTQQHKFVNWQCDGEYRGDDFTAAVTLGNPDVLVG---SGILVAHYLQSLSPSLVLGGELVYHKRP---GEEGTVTSLVGRYTGS--NYVATLTVGG-AGAHASYYHKANDQLQVGVEFEASTRMQ-----------------ETSVSFGYQLDVPKANLLFKGSLDSNWVVGATLEKKLLPLPLSLALGAFLNHRKNKFQCGFGVTIG---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9U4L6-1", "uniprot_id": "TO401_DROME", "id": "Q9U4L6-1", "name": "Mitochondrial import receptor subunit TOM40 homolog 1", "aln": "MGNVLAASSG-----------APGS-GASNLGLGLQEPA--------PLPSNSGSLTESSSSAEGLDSLAAAKDAALENPGTVEELHKKC-KDIQAIT--FEGAKIMLNKGLSN--HFQVSHTINMSNVVPSGYRFGATYVGTKEFSPTEAFPVLLGDIDPAGNLNANVIHQFSARLRCKFASQIQESKVVASQLTTDYRGSDYTLSLTVANPSIFTN---SGVVVGQYLQSVTPALALGSELAYQFGPNVPGRQIAIMSVVGRYTAG--SSVWSGTLGQ-SGLHVCYYQKASDQLQIGAEVETSLRMQ-----------------ESVATLAYQIDLPKANLVFRGGIDSNWQIFGVLEKRLAPLPFTLALSGRMNHVKNNFRLGCGLMIG---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z6L1-1", "uniprot_id": "TO402_DROME", "id": "A1Z6L1-1", "name": "Mitochondrial import receptor subunit TOM40 homolog 2", "aln": "MGNVMASTAD-----------AESSRGRGHLSAGLRLP---------EAPQYSGGVP--PQMVEALK--AEAKKPELTNPGTLEELHSRC-RDIQANT--FEGAKIMVNKGLSN--HFQVTHTINMNSAGPSGYRFGATYVGTKQYGPTEAFPVLLGEIDPMGNLNANVIHQLTSRLRCKFASQFQDSKLVGTQLTGDYRGRDYTLTLTMGNPGFFTS---SGVFVCQYLQSVTKRLALGSEFAYHYGPNVPGRQVAVLSAVGRYAFG--DTVWSCTLGP-AGFHLSYYQKASDQLQIGVEVETNIRQQ-----------------ESTATVAYQIDLPKADLVFRGSLDSNWLISGVLEKRLQPLPFSLAISGRMNHQKNSFRLGCGLMIG---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23644-1", "uniprot_id": "TOM40_YEAST", "id": "P23644-1", "name": "Mitochondrial import receptor subunit TOM40", "aln": "MSAPTPLAEAS---------QIPTIPALSPLTAKQSKG-----------NFFSSNPISSFVVDTYKQLHSHRQSLELVNPGTVENLNKEVSRDVFLSQYFFTGLRADLNKAFSMNPAFQTSHTFSIGSQALPKYAFSALFANDN--------LFAQGNIDNDLSVSGRLNYGWDKKNISKVNLQISDGQPTMCQLEQDYQASDFSVNVKTLNPSFSEKGEFTGVAVASFLQSVTPQLALGLETLYSRTDG-SAPGDAGVSYLTRYVSKKQDWIFSGQLQANGALIASLWRKVAQNVEAGIETTLQAGMVPITDPLMGTPIGIQPTVEGSTTIGAKYEYRQS--VYRGTLDSNGKVACFLERKVLPT-LSVLFCGEIDHFKNDTKIGCGLQFETAGNQELLMLQQGLDADGNPLQALPQL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VF44-1", "uniprot_id": "Q9VF44_DROME", "id": "Q9VF44-1", "name": "Mitochondrial import receptor subunit TOM40 homolog 2", "aln": "MSCKNCPPYK-------------------NSELGIFFP-------------DCFERVSGHCN--------------KKNPGNVQNLHILA-HRVMPKF--YDGIELDYLHRLAP--NKYITAAWVLSHIRPSGFRFGGLYTFRVQDDTMYTPTIMGDIHPTSLAANLNILYYPFQSLRMEAVLQKAREAAVESQYTIEWTRPCDTWTANFYN--VRNE---SGRCTMSVMRSVSAHWALGGELLLEWNDP--QKLTPDLALAARYSHY--NYSLAATASR-QGLDVTYWQRIHPHIQMANLLAWNRNTR-----------------KTIATICYQWNFWNS--AVHGMFDSDASVGFMWTKYLTHLPLQMGFSVVMNLPTDRFAFGMRFVLDPSGLRRGE-------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ***..:: : : : * . : :: : :. . : : :. . . .: : * * :: : . * . : . ::*:: .** * . : :* : . ::: ::: . . . :. : :: :* .:*: : : : . : : :: : * . . ", "identical_positions": 16, "similar_positions": 70, "identity": "3.82%" }, { "cls_id": "homologset.agr.SGD:S000004818", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P30835-1", "uniprot_id": "PFKAL_RAT", "id": "P30835-1", "name": "ATP-dependent 6-phosphofructokinase, liver type", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATVDLEKLRMSGAG---KAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGG-ENIKPANWLSVSNIIQLGGTIIGSARCKAFTTREGRLAAAYNLLQHGITNLCVIGGDGSLTGANIFRNEWGSLLEELVKEGKISESTAQNYAHLSIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPED-GWENFMCERLGETRSRGSRLNIIIIAEGAIDRHGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRVLSSKMGMEAVMALLEATPDTPACVVSLSGNQSVRLPLMECVQVTKDVQKAMDEKRFDEAIQLRGRSFENNWKIYKLLAHQKVSKEKSNFS--------LAILNVGAPAAGMNAAVRSAVRTGISEGHTVYVVHDGFEGLAKGQ-VQEVGWHDVAGWLGRGGSMLGTKRTLPKPH-LEAIVENLRTYNIHALLVIGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKANVEHMTEKMKTDIQRG----LVLRNEKCHEHYTTEFLYNLYSSEGRGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWMS------EKLRDVYRK-GRVFANAPDSACVIGLRKKVVAFSSVTELKK-ETDFEHRMPREQWWLNLRLMLKMLAHYRISMADYVSGELEHVTRRTLSIDKGF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12382-1", "uniprot_id": "PFKAL_MOUSE", "id": "P12382-1", "name": "ATP-dependent 6-phosphofructokinase, liver type", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATVDLEKLRMSGAG---KAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGG-ENIKPANWLSVSNIIQLGGTIIGSARCKAFTTREGRLAAAYNLLQHGITNLCVIGGDGSLTGANIFRNEWGSLLEELVKEGKISESTAQNYAHLTIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPED-GWENFMCERLGETRSRGSRLNIIIIAEGAIDRHGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVSLSGNQSVRLPLMECVQVTKDVQKAMDEERFDEAIQLRGRSFENNWKIYKLLAHQKVSKEKSNFS--------LAILNVGAPAAGMNAAVRSAVRTGISEGHTVYIVHDGFEGLAKGQ-VQEVGWHDVAGWLGRGGSMLGTKRTLPKPH-LEAIVENLRTYNIHALLVIGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKANVEHMTEKMKTDIQRG----LVLRNEKCHEHYTTEFLYNLYSSEGRGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWVS------EKLRDVYRK-GRVFANAPDSACVIGLRKKVVAFSPVTELKK-ETDFEHRMPREQWWLNLRLMLKMLAHYRISMADYVSGELEHVTRRTLSIDKGF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17858-1", "uniprot_id": "PFKAL_HUMAN", "id": "P17858-1", "name": "ATP-dependent 6-phosphofructokinase, liver type", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAVDLEKLRASGAG---KAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGG-ENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPED-GWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFS--------LAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQ-VQEVGWHDVAGWLGRGGSMLGTKRTLPKGQ-LESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRG----LVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLS------EKLREVYRK-GRVFANAPDSACVIGLKKKAVAFSPVTELKK-DTDFEHRMPREQWWLSLRLMLKMLAQYRISMAAYVSGELEHVTRRTLSMDKGF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47857-1", "uniprot_id": "PFKAM_MOUSE", "id": "P47857-1", "name": "ATP-dependent 6-phosphofructokinase, muscle type", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTHEEHHAAKTLGIG---KAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGG-EHIREATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAHNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLLNDLQKDGKITAEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIVEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDD-DWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKRFDEAIKLRGRSFMNNWEVYKLLAHVRPPVSKGGLHT-------VAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQ-IEEAGWSYVGGWTGQGGSKLGTKRTLPKKN-LEQISANITKFNIQGLVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSIGADTALNTICTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQVNVEHLVQKMKTTVKRG----LVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPTPFDRNFATKMGAKAMNWMS------GKIKESYRN-GRIFANTPDSGCVLGMRKRALVFQPVTELKD-QTDFEHRIPKEQWWLKLRPILKILAKYEIDLDTSDHAHLEHISRKRSGEAAV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47858-1", "uniprot_id": "PFKAM_RAT", "id": "P47858-1", "name": "ATP-dependent 6-phosphofructokinase, muscle type", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTHEEHHEAKTLGIG---KAIAVLTSGGDAQGMNATVRAVVRVGIFTGLRVFFVHEGYQGLVDGG-EHIREATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAHNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLLNDLQKDGKITAEERTKSSYLNIVFLVGSIDNDFCGTDMTIGTDSALHRIVEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDD-DWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGSRMGVEAVMALLEGTPDTPACVVSLSGNTAVRLPLMECVQVTKDVTKAMDEKRFDEAIKLRGRSFMNNWEVYKLLAHVRPPVSKGGLHT-------VAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQ-IEEAGWSYVGGWTGQGGSKLGTKRTLPKKN-LEQISANITKYNIQGLVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSIGADTALNTICTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQVNVEHLVQKMKTTVKRG----LVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGNPTPFDRNFATKMGAKATNWMS------GKIKESYRN-GRIFANTPDSGCVLGMRKRALVFQPVTELKD-QTDFEHRIPKEQWWLKLRPILKILAKYEIDLDTSDHAHLEHISRKRSGEAAV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08237-1", "uniprot_id": "PFKAM_HUMAN", "id": "P08237-1", "name": "ATP-dependent 6-phosphofructokinase, muscle type", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTHEEHHAAKTLGIG---KAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGG-DHIKEATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDD-DWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLRGRSFMNNWEVYKLLAHVRPPVSKSGSHT-------VAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQ-IEEAGWSYVGGWTGQGGSKLGTKRTLPKKS-FEQISANITKFNIQGLVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSVGADTALNTICTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQANVEHLVQKMKTTVKRG----LVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPTPFDRNFATKMGAKAMNWMS------GKIKESYRN-GRIFANTPDSGCVLGMRKRALVFQPVAELKD-QTDFEHRIPKEQWWLKLRPILKILAKYEIDLDTSDHAHLEHITRKRSGEAAV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A7I7-1", "uniprot_id": "A0AB13A7I7_DANRE", "id": "A0AB13A7I7-1", "name": "ATP-dependent 6-phosphofructokinase", "aln": "--METVWDNCVCVCQLCVCVWDVFVCVCQISVCLLELCVCLLRLSVLLFHWIPHIGLTVWIWQRTHRKT-----------------------------------------------------QFDANHVYGSKDPSYCDESKTEVLADGKTTSTTCFDSGLDDLSCSSATHNSCRLFEMQHSAPVDPTKMGVG---RAIAVLTSGGDAQGMNAAVRATVRVGIYTGAKVYFVHEGYQGLVDGG-DNIRQATWESVSMMLQLGGTVIGSARCQDFRTKEGRAKAACNLVKLGITNLCVIGGDGSLTGANEFRNEWSELLQILQKTGKITAEEAKCSSHLNIVGMVGSIDNDFCGTDMTIGTDSALHRIMEVVDAITTTAQSHQRAFILEVMGRHCGYLALVTALSCGADWVFIPEMPPDE-GWEDHLCRRLTYQRSIGNRLNVIIVAEGALDRHGKPITCDIIKNLVTKKLGFDTRATILGHVQRGGTPSAFDRILGSRMGVEAVMALLEATPDTPACVVSLSGNMAVRLPLMECVQVTKEVTKAMAEGRFEEAIKLRGKSFENNWNTYKLLAHVTAPDVKSNIN--------IAILNVGAPCAGMNAAVRSAVRIGILQGHNMLAVHDGFEGLANGT-IEPMAWGYVGGWTGKGGSILGTKRSLPANM-IEEISLNIAKFNIHALVIIGGFEAFVGGLELVTAREKYEELCIPLVVIPATVSNNVPGSDFSVGADTALNTITTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYVFEDPFGIHDLEANVEHLLEKMKTTVKRG----LILRNEKCNANYTTDFLFNLYSEEGKGVFDCRKNVLGHMQQGGTPTPFDRNFGTKMGAKAVLWLT------DKLKECYRH-GRIFANTPDSACVLGMRKRAMLFQPLSDLKE-DTDFEHRIPKTEWWLKLRPILKILAKYKISLDTSETATMEHVIKKRGGV----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P52034-1", "uniprot_id": "PFKA_DROME", "id": "P52034-1", "name": "ATP-dependent 6-phosphofructokinase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSEINQRFLARGSQK-DKGLAVFTSGGDSQGMNAAVRACVRMAIYLGCKVYFIREGYQGMVDGG-DCIQEANWASVSSIIHRGGTIIGSARCQDFRERQGRLKAANNLIQRGITNLVVIGGDGSLTGANLFRQEWSSLLDELVKNKTITTEQQEKFNVLHIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAISSTAYSHQRTFIMEVMGRHCGYLALVGGLACEADFIFIPEMPPKV-DWPDRLCSQLAQERSAGQRLNIVIVAEGAMDREGHPITAEDVKKVIDERLKHDARITVLGHVQRGGNPSAFDRILACRMGAEATLALMEATKDSVPVVISLDGNQAVRVPLMECVERTQAVAKAMAEKRWADAVKLRGRSFERNLETYKMLTRLKPPKENFDADGKGIEGYRLAVMHIGAPACGMNAAVRSFVRNAIYRGDVVYGINDGVEGLIAGN-VRELGWSDVSGWVGQGGAYLGTKRTLPEGK-FKEIAARLKEFKIQGLLIIGGFESYHAAGQIADQRDNYPQFCIPIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRIRQSAQGTKRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSIKDLQQDVYHMASKMAEGVSRG----LILRNEKASENYSTDFIYRLYSEEGKGLFTCRMNILGHMQQGGSPTPFDRNMGTKMAAKCVDWLA------AQIKANIDANGVVNCKSPDTATLLGIVSRQYRFSPLVDLIA-ETNFDQRIPKKQWWLRLRPLLRILAKHDSAYEEEGMYITVEEECDTDAVA---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P16862-1", "uniprot_id": "PFKA2_YEAST", "id": "P16862-1", "name": "ATP-dependent 6-phosphofructokinase subunit beta", "aln": "MTVTTPFVNGTSYCTVTAYSVQSYKAAIDFYTKFLSLENRSSPDENSTLLSNDSISLKILLRPDEKINKNVEAHLKELNSITKTQDWRSHATQSLVFNTSDILAVKDTLNAMNAPLQGYPTELFPMQLYTLDPLGNVVGVTSTKNAVSTKPTPPPAPEASAESGLSSKVHSYTDLAYRMKTTDTYPSLPKPLNRPQKAIAVMTSGGDAPGMNSNVRAIVRSAIFKGCRAFVVMEGYEGLVRGGPEYIKEFHWEDVRGWSAEGGTNIGTARCMEFKKREGRLLGAQHLIEAGVDALIVCGGDGSLTGADLFRSEWPSLIEELLKTNRISNEQYERMKHLNICGTVGSIDNDMSTTDATIGAYSALDRICKAIDYVEATANSHSRAFVVEVMGRNCGWLALLAGIATSADYIFIPEKPATSSEWQDQMCDIVSKHRSRGKRTTIVVVAEGAIAADLTPISPSDVHKVLVDRLGLDTRITTLGHVQRGGTAVAYDRILATLQGLEAVNAVLESTPDTPSPLIAVNENKIVRKPLMESVKLTKAVAEAIQAKDFKRAMSLRDTEFIEHLNNFMAINSADHNEPKLPKDKR----LKIAIVNVGAPAGGINSAVYSMATYCMSQGHRPYAIYNGWSGLARHESVRSLNWKDMLGWQSRGGSEIGTNRVTPEEADLGMIAYYFQKYEFDGLIIVGGFEAFESLHQLERARESYPAFRIPMVLIPATLSNNVPGTEYSLGSDTALNALMEYCDVVKQSASSTRGRAFVVDCQGGNSGYLATYASLAVGAQVSYVPEEGISLEQLSEDIEYLAQSFEKAEGRGRFGKLILKSTNASKALSATKLAEVITAEADGRFDAKPAYPGHVQQGGLPSPIDRTRATRMAIKAVGFIKDNQAAIAEARAAEENFNADDKTISDTAAVVGVKGSHVVYNSIRQLYDYETEVSMRMPKVIHWQATRLIADHLVGRKRVD----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :.:.*:*****: ***: *** .* .*: * :.:.: ***:*:* ** : *: * .* *** **:*** * ::** .* :*:: *: * * *********: **.** .*:. * *: * * *******:. ** ***: :**.** : :* : :** **.*:*::*****:**:***: .:: **::**** *. * : :* : *: *.* .::::****: . **: . ::.:: .:* *:* * ********.. *:**:*. * **. *::*.* *: . ::::. * ** ****.*: *: * :*: : * .**. .* .: : : : : :*::::***. *:*:** * . : .*. : :* .** :. * : ** .:**: :**:* * : * : : :..*:::****:: . :: * : : * : :**:*:******:::*:*.**.:* ** ::*** .*: *.*::: ** .***** :.:* **:.:*: *: : :.:*. :: :: ..: ** *:*:. :. :: : .: : *. * * .: **:**** *:*:**. .*::. *. :: : : . . .*:. ::*: :..: :* :*:.. *:*: * * : *. ", "identical_positions": 242, "similar_positions": 236, "identity": "24.57%" }, { "cls_id": "homologset.agr.SGD:S000004820", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K1F2-1", "uniprot_id": "A0A0G2K1F2_RAT", "id": "A0A0G2K1F2-1", "name": "acetyl-CoA carboxylase", "aln": "MVLLLFLTCLVFSCLTISWLKIWGKMTDSKPLSNSKVDASLLSSKEESFSASDQSEEHG----DCSCPLTTPDQEELASHGGPVDASQQRNSVPSSHQKPPRNPLSSNDTCSSPELQTNRVAAPGSEVPEANGLPFPARPQTQRTGSPTREDKKQAHIKRQLMTSFILGSLDDNSSDEDPS----ASSFQTSSRKGSRA-SLGTLSQEAALNTADPESHTPTMRPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGNRVIETVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGPNNNNYANVELIIDIAKRIPVQAVWAGWGHASENPKLPELLCKHE--IAFLGPPSEAMWALGDKISSTIVAQTLQIPTLPWSGSGLTVEWTEDSQHQGKCISVPEDVYEQGCVRDVDEGLQAAEKVGFPLMIKASEGGGGKGIRRAESAEDFPMLFRQVQSEIPGSPIFLMKLAQNARHLEVQVLADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAAPAVFEFMEQCAVLLAKTVGYVSAGTVEYLYSQ-DGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPVSFETPLSPPIARGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLVNLLETESFQNNDIDTGWLDHLIAQRVQAE-KPDIMLGVVCGALNVADAMFRTCMTEFLHSLERGQVLPADSLLNIVDVELIYGGIKYVLKVARQSLTMFVLIMNGCHIEIDAHRLNDGGLLLSYNGSSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLMQYTVEDGQHVEVGSSYAEMEVMKMIMTLNVQESGRVKYIKRPGAVLEAGCVVAKLELDDPSKVHAAQPFTGELPAQQTLPILGERLHQVFHSVLENLTNVMNGYCLPEPFFSMKLKDWVEKLMMTLRHPSLPLLELQEIMTSVAGRIPVPVEKAVRRVMAQYASNITSVLCQFPSQQCWASGMLGKHSTTELQPELLKIATILDCHAATLQRKVDREAFFMNTQSIVQLIQRYRSGTRGYMKAVVLDLLRRYLNVEHHFQQA--HYDKCVINLREQFKPDMTRVLDCIFSHSQVAKKNQLVTMLIDE---LCGPDPTLSEELTSILKELTQLSRSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQ--------FCPENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRELPDGTCVVEFQFMLPSSHPN----------------------RMAMPINVSD--PDLLRHSKELFMDSGFSPLCQRMGAMVAFRRFEEFTRNFDEVISCFANVPTDTPLFSKACTSLYSEEDSKPS-----------------FFLSQSLQEEPIHILNVAIQCADHMEDERLVPVFRAFVQSKKHILVDYGLRRITFLIAQE---------------REFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRNFDLTAVPCANHKMHLYLGAAKVKEGLEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNN-TSVRTDCNHIFLNFVPTVIMDPLKIEESVRAMVMRYGSRLWKLRVLQAEVKINIRQTTSDCAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSFGNKQGSLHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWG--------SPEKYPKDILTYTELVLDSQGQLVEMNRLPGCNEVGMVVFKMRFKTPEYPEGRDTIVIGNDITFQIGSFGIGEDFLYLRASEMARTEGIPQIYLAANSGARMGLSEEIKQIFQVAWVDPEDPYKGFRYLYLTPQDYTQISSQ---NSVHCKHIEDEGESRYVIVDVIGKDSSLGVENLRGSGMIAGEASLAYEKNVTISMVTCRAIGIGAYLVRLGQRVIQVENSHIILTGAGALNKVLGREVYTSNNQLGGVQIMHTNGVSHVTVPDDFEGVCTILEWLSYIPKDNQSPVPIITPSDPIDREIEFTPTK-APYDPRWLLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRSVEVAVPADPANLDSEAKIIQQAGQVWFPDSAFKTAQVIRDFNQ-EHLPLMIFANWRGFSGGMKDMYEQMLKFGAYIVDSLRLFKQPVLIYIPPGAELRGGAWVVLDSSINPLCIEMYADKESRGGVLEPEGTVEIKFRKKDLVKTIRRIDPVCKKLLGQLGTAQLPDK--DRKELESQLKAREDLLLPIYHQVAVQFADLHDTPGHMLEKGIISDVLEWKTTRTYFYWRLRRLLLEAQVKQEILRASPELSHEHTQSMLRRWFVETEGAVKAYLWDSNQVVVQWLEQHWSARDNLRSTIRENINYLKRDSVLKTIQSLVQEHPEATMDCVAYLSQHLTPAEQMQVVQLLSTTESPASH------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q4Z2-1", "uniprot_id": "ACACB_MOUSE", "id": "E9Q4Z2-1", "name": "Acetyl-CoA carboxylase 2", "aln": "MVLLLFLTCLVFSCLTFSWLKIWGKMTDSKPLTNSKVEANLLSS-EESLSASELSGEQ----------LQEHGDHSCLSYRGPRDASQQRNSLPSSCQRPPRNPLSSNDTWPSPELQTNWTAAPGPEVPDANGLSFPARPPSQRTVSPSREDRKQAHIKRQLMTSFILGSLDDNSSDEDPS----AGSFQNSSRKSSRA-SLGTLSQEAALNTSDPESHAPTMRPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGNRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGPNNNNYANVELIIDIAKRIPVQAVWAGWGHASENPKLPELLCKHE--IAFLGPPSEAMWALGDKIASTIVAQTLQIPTLPWSGSGLTVEWTEDSRHQGKCISVPEDVYEQGCVKDVDEGLQAAEKIGFPLMIKASEGGGGKGIRKAESAEDFPMLFRQVQSEIPGSPIFLMKLAQNARHLEVQVLADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAAPAVFEFMEQCAVLLAKMVGYVSAGTVEYLYSQ-DGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPIPFETPLSPPIARGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLVNLLETESFQNNDIDTGWLDHLIAQRVQAE-KPDIMLGVVCGALNVADAMFRTCMTEFLHSLERGQVLPADSLLNIVDVELIYGGIKYALKVARQSLTMFVLIMNGCHIEIDAHRLNDGGLLLSYNGSSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLMQYTVEDGDHVEAGSSYAEMEVMKMIMTLNVQESGRVKYIKRPGVILEAGCVVARLELDDPSKVHAAQPFTGELPAQQTLPILGEKLHQVFHGVLENLTNVMSGYCLPEPFFSMKLKDWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKAVRRVMAQYASNITSVLCQFPSQ---------------------QIATILDCHAATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKAVVLDLLRKYLNVEHHFQQA--HYDKCVINLREQFKPDMTQVLDCIFSHSQVAKKNQLVTMLIDE---LCGPDPTLSDELTSILCELTQLSRSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQ--------FCPENLKKLILSETTIFDVLPTFFYHENKVVCMASLEVYVRRGYIAYELNSLQHRELPDGTCVVEFQFMLPSSHPN----------------------RMAVPISVSN--PDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEEFTRNFDEVISCFANVQTDTLLFSKACTSLYSEEDSK------------------------SLREEPIHILNVAIQCADHMEDEALVPVFRAFVQSKKHILVDYGLRRITFLVAQE---------------REFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRNFDLTAVPCANHKMHLYLGAAKVKEGLEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNN-TSVRTDCNHIFLNFVPTVIMDPLKIEESVRDMVMRYGSRLWKLRVLQAEVKINIRQTTSDSAIPIRLFITNESGYYLDISLYREVTDSRSGNIMFHSFGNKQGSLHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWG--------SPEKYPKDILTYTELVLDSQGQLVEMNRLPGCNEVGMVAFKMRFKTPEYPEGRDAVVIGNDITFQIGSFGIGEDFLYLRASEMARTEGIPQIYLAANSGARMGLAEEIKQIFQVAWVDPEDPHKGFRYLYLTPQDYTQISSQ---NSVHCKHIEDEGESRYVIVDVIGKDANLGVENLRGSGMIAGEASLAYEKTVTISMVTCRALGIGAYLVRLGQRVIQVENSHIILTGAGALNKVLGREVYTSNNQLGGVQIMHTNGVSHVTVPDDFEGVCTILEWLSFIPKDNRSPVPITTPSDPIDREIEFTPTK-APYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQVIRDFNK-ERLPLMIFANWRGFSGGMKDMYEQMLKFGAYIVDGLRLYEQPILIYIPPCAELRGGSWVVLDSTINPLCIEMYADKESRGGVLEPEGTVEIKFRKKDLVKTIRRIDPVCKKLVGQLGKAQLPDK--DRKELEGQLKAREELLLPIYHQVAVQFADLHDTPGHMLEKGIISDVLEWKTARTFFYWRLRRLLLEAQVKQEILRASPELNHEHTQSMLRRWFVETEGAVKAYLWDSNQVVVQWLEQHWSAKDGLRSTIRENINYLKRDSVLKTIQSLVQEHPEVIMDCVAYLSQHLTPAERIQVAQLLSTTESPASS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00763-1", "uniprot_id": "ACACB_HUMAN", "id": "O00763-1", "name": "Acetyl-CoA carboxylase 2", "aln": "MVLLLCLSCLIFSCLTFSWLKIWGKMTDSKPITKSKSEANLIPS-QEPFPASDNSGETPQRNGEGHTLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGTGTQGLEATDTNGLSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDSV----AGSSRESTRKGSRA-SLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKNG--VAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQ-DGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAE-KPDIMLGVVCGALNVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIMNGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVARLELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIKLKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFPSQ---------------------QIATILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRVEHHFQQA--HYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDE---LCGPDPSLSDELISILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQ--------FCPENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVEFQFMLPSSHPN----------------------RMTVPISITN--PDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTRNFDEVISCFANVPKDTPLFSEARTSLYSEDDCK------------------------SLREEPIHILNVSIQCADHLEDEALVPILRTFVQSKKNILVDYGLRRITFLIAQE---------------KEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELNRMRNFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNN-TSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGSRLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSFGNKQGPQHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWG--------SPDKYPKDILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIGSFGPGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFKYLYLTPQDYTRISSL---NSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSLAYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSR-APYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNR-EKLPLMIFANWRGFSGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYADKESRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDK--DRKDLEGRLKAREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVKQEILQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIRENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PKW2-1", "uniprot_id": "A0A8M9PKW2_DANRE", "id": "A0A8M9PKW2-1", "name": "acetyl-CoA carboxylase", "aln": "-------------------------MPSQTPISDCAG------------------------------------EHSPPMDPGLSSTSPRNEGIPPSATSDPTD-------------QSNITVS-----------HIESHRPRFGSGAQAKEKLK-----------FILGASEDNSSDDEPL----VKNQTTTHQPKNTE-TLNAEPTASSEMPPTPVPSTG-LRPSMSGPHLLKKGKEHRKMEVHRDFTVASPAEFVTRFGGNRIIDKVLIANNGIAAVKCMRSIRRWSYEMFRNERTIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVEMIVDIAKRIPVQAVWAGWGHASENPKLPELLHKSG--ICFLGPSSKAMWALGDKVASSIVAQSAGIPTLPWSGTGLSVEWAEEEQRQGRLISVPPELYVQGCVKDVDEGLASAEKIGYPVVIKASEGGGGKGIRKVESSEDFPSLFRQVQAEVPGSPIFIMQLAEHARHLEVQILADQYGNAISLFGRDCSIQRRHQKIIEEAPASIASTITFEQMEQYAVRLAKMVGYVSAGTVEYLFSE-DGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGIPLYRIKDIRVLFGEAPWGDTTINFESPECMPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVGATGGLHEFADSQFGHCFSWGENREEAISNMVVAMKELSIRGDFRTTVEYLIKLLETESFRNNDIDTGWLDHLIADKVQAE-RPDTMLGVVCGALQVADASFRESMSDFLHSLERGQVLPAASLVNTVNVDLIYDGVKYCLKVARQSPTTYVIIMNDSDIEVDVHRLSDGGLLLSYGGSSYTTYMKEEIDRYRVTVGNKTCVFEKERDPTVLRSPSAGKLLQYVVTDGSHVSASQPYAEIEVMKMVMTLHVQHSGCIRFLKRPGTVLEPGCIVALMDLDDPSCIHQVKPNTEPLPAQEPLPMVGERLHQVFHNVLENLVKIMDGYCLPEPYFSQKLKNWVDTLMKTLRDPSLPLLELQEIMTSVAGRIPVTVEKAIRKVMAQYASNITSVLCQFPSQ---------------------RIANILDSHAATLQRKADREIFFMNTQSIVQLVQRYRSGIRGYMKSVVLDLLKHYLQVEMQFQQA--HYDKCVINLREQYKPDMTPVLECIFSHAQVSKKNILVTMLIDQ---LCGRDPMLADELMVILDELTQLSKMENSKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQ--------FCPENLKKLILSETSIFDVLPSFFYHNNRVVCMAALEVYVRRAYIAYELNSLQHHQLQDGTCAVDFQFMLPSSHPNREPNATVSQHMPKSTGSSPTLNRLTLPVNDSGEFPAMRRQGSELFLEGALSPPCQRMGAMVAFHSFDHFKRCFDEVICRFVDPLCESSLFFDGCSTFCDGESCK------------------------NMKENPIHIINVSIKQADTEDDDALVTAFTAFAHSKKSLLYDYGIRRVTFLVAQK---------------REFPKYFTFRARDEFHEDRIYRNLEPALAFQLELNRMRNFDLKAVPCAHHRMQLYLGAARVEEGAEVTDYRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFSN-TPTRTDCNHIFLNFVPTVIMDPYKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTTTGDVIPIRLFLTNESGYYLDISLYKEVNDPSSGQIMFQSYGDKQGPLNGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWG--------PGDSYPKDVLMCNELVLDSQGNLVQMNRLPGDNEVGMVAFRMRMKTPEYPEGRDIIVICNDITHMIGSFGPQEDQLFMRASELARAEGIPRIYISANSGARIGLAEEIRHMFQVAWIDPEDPYKGFKYLYLTPQDYTRISSS---NSVHCHHVEEGGESRYILTDIIGKEEGIGVENLRGSGTIAGETSQAYKEIITISMVTCRAIGIGAYLVRLGQRVIQVENSHIILTGAGALNKVLGREVYTSNNQLGGVQIMHNNGVTHSTVPDDFEGVLTILQWLSYMPKSNQSPVPIKPATDPVDREIDFVPTK-APYDPRWLLCGRPHPTVKGAWQSGFFDHGSFLEIMATWAQTVVVGRARLGGIPLGVIAVETRTVELAIPADPANLDSEAKLLQQAGQVWFPDSAYKTAQAIEDFNR-EKLPLMVFANWRGFSGGMKDMYDQVLKFGSYIVDALREFSQPVLVYIPPNAELRGGSWVVIDPTINLQHMELYADRESRGGVLEAEGTVEIKFRKKDLLKTMRRIDPVYSRLAEQLGKPDLPSQ--ERKDLEAKLKSREEFLLPIYHQVAVQFVDLHDTPGRMQEKGVITDILDWKTARSFFYWRLRRLLLEEVVKKEIMQANQDLSNGHIQSMLRRWFVETEGAVKAYLWDNNKVVVEWLENNLSQQDGTRSVIRENIKCIKRDYALKHIRSLVQANPEVTMDCIIHMAQNITPSQRAKVCHLLATMDNSTTS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5SWU9-1", "uniprot_id": "ACACA_MOUSE", "id": "Q5SWU9-1", "name": "Acetyl-CoA carboxylase 1", "aln": "----------------------------------------------------------------------------------MDEPSPLAKTLELN-----------------------------------------------------------------QHSRFIIGSVSEDNSEDEISNLVKLDLEE-KEGSLSPA-SVSSDTLSDLGISGLQDGLAFHMRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNG--IAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSK-RILNVPQDLYEKGYVKDVDDGLKAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQ-DGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLFRIKDIRMMYGVSPWGDAPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQLNRIDTGWLDRLIAEKVQAE-RPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQVLPAHTLLNTVDVELIYEGIKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAVESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPQIQSTALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPLNVEKSIKKEMAQYASNITSVLCQFPSQ---------------------QIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNG--HYDKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLVTMLIDQ---LCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQ--------FCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNR--------------GNIPTLNRMSFASNLNHYGMTHVASVSDVLLDNAFTPPCQRMGGMVSFRTFEDFVRIFDEIMGCFCDSPPQSPTFPESGHTSLYDED-------------------------KVPRDEPIHILNVAIKTDGDIEDDRLAAMFREFTQQNKATLVEHGIRRLTFLVAQKDFRKQVNCEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNN-TNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTTTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDILTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMSLKSPEYPDGRDIIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVDPEDPYKGYKYLYLTPQDYKRVSAL---NSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGSGMIAGESSLAYDEVITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHSTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPIDRIIEFVPTK-APYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNR-EGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECSQPVMVYIPPQAELRGGSWVVIDPTINPRHMEMYADRESRGSVLEPEGTVEIKFRKKDLVKTMRRVDPVYIRLAERLGTPELSPT--ERKELESKLKEREEFLIPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLRRLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTEEDGVRSVIEENIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILSTMDSPST-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11497-1", "uniprot_id": "ACACA_RAT", "id": "P11497-1", "name": "Acetyl-CoA carboxylase 1", "aln": "----------------------------------------------------------------------------------MDEPSPLAKTLELN-----------------------------------------------------------------QHSRFIIGSVSEDNSEDEISNLVKLDLEE-KEGSLSPA-SVSSDTLSDLGISALQDGLAFHMRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGANNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNG--IAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSK-RILNVPQDLYEKGYVKDVDDGLKAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQ-DGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLFRIKDIRMMYGVSPWGDAPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQLNRIDTGWLDRLIAEKVQAE-RPDTMLGVVCGALHVADVNLRNSISNFLHSLERGQVLPAHTLLNTVDVELIYEGIKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAVESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPQIQSTALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSKVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPLNVEKSIKKEMAQYASNITSVLCQFPSQ---------------------QIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNG--HYDKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLVTMLIDQ---LCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYDVRHNQVESIFLSAIDMYGHQ--------FCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNR--------------GNIPTLNRMSFASNLNHYGMTHVASVSDVLLDNAFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSPPQSPTFPESGHTSLYDED-------------------------KVPRDEPIHILNVAIKTDGDIEDDRLAAMFREFTQQNKATLVEHGIRRLTFLVAQKDFRKQVNCEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNN-TNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTTTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDILTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMSLKSPEYPDGRDVIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVDSEDPYKGYKYLYLTPQDYKRVSAL---NSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGSGMIAGESSLAYDEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHCTVCDDFEGVFTVLHWLSYMPKNVHSSVPLLNSKDPIDRIIEFVPTK-APYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSVPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNR-EGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECSQPVMVYIPPQAELRGGSWVVIDPTINPRHMEMYADRESRGSVLEPEGTVEIKFRKKDLVKTMRRVDPVYIRLAERLGTPELSPT--ERKELESKLKEREEFLIPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLRRLLLEDLVKKKIHSANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTEEDGVRSVIEENIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILSTMDSPST-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13085-1", "uniprot_id": "ACACA_HUMAN", "id": "Q13085-1", "name": "Acetyl-CoA carboxylase 1", "aln": "----------------------------------------------------------------------------------MDEPSPLAQPLELN-----------------------------------------------------------------QHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPA-SVGSDTLSDLGISSLQDGLALHIRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNG--IAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSK-RILNVPQELYEKGYVKDVDDGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQ-DGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGVSPWGDSPIDFEDSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQMNRIDTGWLDRLIAEKVQAE-RPDTMLGVVCGALHVADVSLRNSVSNFLHSLERGQVLPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAVESGCIHYVKRPGAALDPGCVLAKMQLDNPSKVQQAELHTGSLPRIQSTALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSKVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQ---------------------QIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNG--HYDKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLVTMLIDQ---LCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQ--------FCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNR--------------GNIPTLNRMSFSSNLNHYGMTHVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFSDSPPQSPTFPEAGHTSLYDED-------------------------KVPRDEPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATLVDHGIRRLTFLVAQKDFRKQVNYEVDRRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNN-TNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDMLTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTFKSPEYPEGRDIIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVSANSGARIGLAEEIRHMFHVAWVDPEDPYKGYRYLYLTPQDYKRVSAL---NSVHCEHVEDEGESRYKITDIIGKEEGIGPENLRGSGMIAGESSLAYNEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHCTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPIDRIIEFVPTK-TPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNR-EGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECCQPVLVYIPPQAELRGGSWVVIDSSINPRHMEMYADRESRGSVLEPEGTVEIKFRRKDLVKTMRRVDPVYIHLAERLGTPELSTA--ERKELENKLKEREEFLIPIYHQVAVQFADLHDTPGRMQEKGVISDILDWKTSRTFFYWRLRRLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLAEWLEKQLTEEDGVHSVIEENIKCISRDYVLKQIRSLVQANPEVAMDSIIHMTQHISPTQRAEVIRILSTMDSPST-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YZ52-1", "uniprot_id": "A0A8M6YZ52_DANRE", "id": "A0A8M6YZ52-1", "name": "acetyl-CoA carboxylase", "aln": "----------------------------------------------------------------------------------MAEQDSTEKKLPAVAA---------------------------------------------------------------LHSHFIVGSVSEENSEDETAGKLDLQLED-NPRSLSPS-SVSSDSTYEMGFDSLDG-PLHNMRPSMSGLHLVKQGRDRRRIDLQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGTNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLHKNG--IAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGTGLTVEWTENDQKK-GIINVPTELYEQGCVHDVEAGLKAAEQVGFPVMVKASEGGGGKGIRKVNCAEDFPNLYRQVQAEVPGSPIFVMQLAKHARHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATSDVFEDMEKCAVKLAKMVGYVSAGTVEYLYSQ-DSSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLHRIKDIRVLYGMQPWGDSPIDFDGLSTTPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQHNSIDTGWLDRLISEKMQAE-RPDTMLGVVSGALHVADVNFRNSVSNFLHSLERGQVLPAHTLLNTVDVELIYEGTKYVLKVTRQSPNSYVVIMNCSSVEVDVHRLSDGGMLLSYDGSSYTTYMKEEVDRYRIIIGNKTCVFEKENDPSVLRSPSAGKLIQYTVEDGGHVFAGQCYAEIEVMKMVMTLTASESGCIHYVKRAGAVLEPGCIIGKLQLDDPSRVQQAELYTGTLPSIQSVALRGEKLHRVFHSTLGHLVHIMNGYCLPEPFFSAKLKEWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPAVEKAIKKEMAQYASNITSVLCQFPSQ---------------------QIANILDSHAATLNRKSEREVFFMNTQSIVQLVQKYRSGIRGHMKAVVMDLLRQYLRVEVQFQHG--HYDKCVFALREENKVDMANVLNYIFSHAQVTKKNCLVTMLIDQ---LCGRDPTLTDELMAILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQ--------FCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCIVEFQFMLPTSHPNR--------------GNIPTLNRMSFSSNLNHYGMVHVASVSDVLLDTSFTPPCQRMGAMVSFRSFQEFTRNIKDVLSCFSDSPPSTPTFPEGGNPVLYREEDS-----------------------KSIQDEPIHILNVAIKTDSDIDDDGLAAMFREFTQSKKSLLFDHGIRRLTFLVAQKDFRKQINCEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFALTAIPCANHKMHLYLGAARVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLHNEAERLLLEAMDELEVAFNN-TTVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTPTGKQIPIRLFLTNESGYYLDISLYKEVTDSRTGQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYVYDFPEMFRQALRKLWQSMDAHANLPKCPLPSELLTFTELVLDSQGQLVQMNRLPGGNEIGMVAWRMTLRTPEYPAGREIIVISNDITHKIGSFGPQEDVLFQQASEMARESGIPRIYIAANSGARIGLAEEIRHMFHVAWQDPVDPYKGFKYLYLTPQDYKKVSAL---NSVHCEHVEDEGESRYKITDIIGKEEGLGVENLRGSGMIAGESSLAYEDIITMNLVTCRAIGIGAYLVRLGQRTIQVENSHIILTGAGALNKVLGREVYTSNNQLGGVQIMHNNGVTHTNVCDDFEGVYTLLHWLSYMPKNMSSPVPILSAKDPIDRAIEFVPTK-APYDPRWMLAGRPNQNIKGAWVSGFFDQGSFLEIMQPWAQSVVVGRARLGGIPTGVVAVETRSVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTAQAIKDFNR-EGLPLIVFANWRGFSGGMKDMYDQVLKFGAYIVDGLREYRQPVLVYIPPQAELRGGSWVVIDPTINPRHMEMYADKDSRGGVLEPEGTVEIKFRKKDLVKTMRRVDPVYMGLAERLGTPELSVS--ERKELESKLKEREEFLLPIYHQVAVQFADLHDTPGRMQEKGVITDILEWSTSRQFFYWRLRRLLLEETVKRKIQCANSELTDGQVQAMLRRWFVEAEGAVKAYLWDSNEDVVEWLERQLAEEEGARSVIDENIKYIRRDHILKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILSTMDTPASS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z784-1", "uniprot_id": "A1Z784_DROME", "id": "A1Z784-1", "name": "", "aln": "-MLITILGTLAAFLAFLLTLIFGRGQKRSKPVQSSAATSATTATTGDSDNGNTNHNSSVIAATATATTTSSKPPIAPAAPPSAVKASDKRFPKACIKKVQFSSESLRSDVDELCDQLKDSALSNLSNDNIRIACHQNNNNSSINKNQNNNSIDISISISKMSETNESNDTAAQSAEGERPSFLVGDEIDERAAEAGEACDEFPLKMQNDVRQNGDISERRKRLRPSMSRGTGLGQDRHQ-----DRDFHIATTEEFVKRFGGTRVINKVLIANNGIAAVKCMRSIRRWAYEMFKNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGSNNNNYANVELIVDIALRTQVQAVWAGWGHASENPKLPELLHKEG--LVFLGPPERAMWALGDKVASSIVAQTAEIPTLPWSGSDLKAQYSG------KKIKISSELFARGCVTNVEQGLAAVNKIGFPVMIKASEGGGGKGIRRVDTTEEFPGLFRQVQAEVPGSPIFVMKLARGARHLEVQLLADQYGNAISLFGRDCSIQRRHQKIIEEAPAIVAQPEVFEDMEKAAVRLAKMVGYVSAGTVEYLYDP-EGRYFFLELNPRLQVEHPCTEMVADVNLPAAQLQIGMGIPLYRLKDIRLLYGESPWGSSVIDFENPPNKPRPSGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVAASGGLHEFADSQFGHCFSWGENRQQARENLVIALKELSIRGDFRTTVEYLITLLETNRFLDNSIDTAWLDALIAERVQSE-KPDILLGVMCGSLHIADRQITESFSSFQTSLEKGQIQAANTLTNVVDVELINDGIRYKVQAAKSGANSYFLLMNSSFKEIEVHRLSDGGLLISLEGASYTTYMKEEVDRYRIVIGNQTCVFEKENDPSLLRSPSAGKLINMIVEDGAHVSKGQAYAEIEVMKMVMTLTSQEAGTVTFVRRPGAVLDAGSLLGHLELDDPSLVTKAQPFKGQFLQPENAPVP-EKLNRVHNTYKSILENTLAGYCLPEPFNAQRLRDIIEKFMQSLRDPSLPLLELQEVIASISGRIPISVEKKIRKLMTLYERNITSVLAQFPSQ---------------------QIASVIDSHAATLQKRADRDVFFLTTQSIVQLVQRYRNGIRGRMKAAVHELLRQYYDVESQFQYG--HYDKCVGLVREHNKDDMQTVVNTIFSHSQVAKKNLLVTLLIDH---LWANEPGLTDELANTLSELTSLNRAEHSRVALRSRQVLIAAHQPAYELRHNQMESIFLSAVDMYGHD--------FHPENLQRLILSETSIFDILHDFFYHSNRAVCNAALEVYVRRAYTSYELTCLQHLELSGGLPLVHFQFLLPTAHPNR------------------LFSRMSSPDGLDQAAAESLGNS------------FVRTGAIAAFDSFEHFEMYSDEILDLLEDFVSPAMVNAKVLEAVEAADSISDSRHSTSINVSLSDPVTRANAAEEAKSTEPIHIVSVAVRETGELDDLQMAQIFGNYCQEHNEELFQRRIRRITFAALKK---------------RQFPKFFTFRARDKFTEDRIYRHLEPASAFHLELNRMKTYDLEALPTANQKMHLYLGKAKVSKGQEVTDYRFFIRSIIRHSDLITKEASFEYLQNEGERVLLEAMDELEVAFSHPHAKRTDCNHIFLNFVPTVIMDPAKIEESVTKMIMRYGPRLWKLRVLQAELKMVIRQSPQSPTQAVRLCIANDSGYFLDISMYTEQTEPETGIIKFKAYGEKQGSLHGHPISTPYMTKDFLQQKRFQAQSNGTTYVYDVPDMFRQMTERHWREFSKARPTVDIRTPDKILIECKELVLEGDNLVEMQRLPGENNCGMVAWRIVLATPEYPNGREIIVIANDLTYLIGSFGIKEDVLFAKASQLARQLKVPRIYISVNSGARIGLAEEVKAMFKIAWEDPEEPDKGFKYLYLSTEDYAQVANL---NSVRAILIEDEGEQRYKITDIIGKDDGLGVENLRYAGLIAGETSQAYEEIVTIAMVTCRTIGIGSYVVRLGQRVIQIDNSHIILTGYAALNKLLGRKVYASNNQLGGTQIMFNNGVTHKTEAIDLDGVYTILDWLSYIPAYIGCDLPIVLPNDRIERPVDFMPTK-SPYDPRWMLGGRVNPVNANDWENGFFDRDSWSEIMASWAKTVVTGRARLGGVPVGVIAVETRTVEVEMPADPANLDSEAKTLQQAGQVWYPDSSYKTAQAIKDFGR-EELPLIVFANWRGFSGGMKDMYEQIVKFGAYIVDGLREYKKPVLIYLPPNAELRGGAWAVLDSLINPRYMETYADPEARGGVLEPEGIVEIKYKEKDLVKTIHRLDPTTIALKKELDEANASGDKVRAAQVDEKIKARIAVLMHVYHTVAVHFADLHDTPERMLEKECISEIVPWRDSRRWLYWRLRRLLLEDAYIKKILRAQDNLSVGQAKQMLRRWLVEEKGATEAYLWDKNEEMVSWYEEQIN----AESIVSRNVNSVRRDAIISTISKMLEDCPDVALDAVVGLCQGLTPVNRGVVVRTLAQMQLNEETSNSNQG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32874-1", "uniprot_id": "HFA1_YEAST", "id": "P32874-1", "name": "Acetyl-CoA carboxylase, mitochondrial", "aln": "---------------------------KGKTIT---------------------------------------HGQSWGARRIHSHFYITIFTITCIR-----------------------------------------------------------------IGQYKLALYLDPYRFYNITGSQIVRLKGQRPEYRKRIFAHSYRHSSRIGLNFPSRRRYSNYVDRGNIHKHTRLPPQFIGLNTVESAQPSILRDFVDLRGGHTVISKILIANNGIAAVKEMRSIRKWAYETFNDEKIIQFVVMATPDDLHANSEYIRMADQYVQVPGGTNNNNYANIDLILDVAEQTDVDAVWAGWGHASENPCLPELLASSQRKILFIGPPGRAMRSLGDKISSTIVAQSAKIPCIPWSGSHIDTIHIDN---KTNFVSVPDDVYVRGCCSSPEDALEKAKLIGFPVMIKASEGGGGKGIRRVDNEDDFIALYRQAVNETPGSPMFVMKVVTDARHLEVQLLADQYGTNITLFGRDCSIQRRHQKIIEEAPVTITKPETFQRMERAAIRLGELVGYVSAGTVEYLYSPKDDKFYFLELNPRLQVEHPTTEMISGVNLPATQLQIAMGIPMHMISDIRKLYGLDPTGTSYIDFKN-LKRPSPKGHCISCRITSEDPNEGFKPSTGKIHELNFRSSSNVWGYFSVGNNGAIHSFSDSQFGHIFAVGNDRQDAKQNMVLALKDFSIRGEFKTPIEYLIELLETRDFESNNISTGWLDDLILKNLSSDSKLDPTLAIICGAAMKAYVFTEKVRNKYLELLRRGQVPPKDFLKTKFPVDFIFDNNRYLFNVAQSSEEQFILSINKSQCEVNVQKLSSDCLLISVDGKCHTVYWKDDIRGTRLSIDSNTIFLEAELNPTQVISPTPGKLVKYLVRSGDHVFAGQQYAEIEIMKMQMPLVAKSDGVIELLRQPGSIIEAGDVIAKLTLDSPSKANESSLYRGELPVLGPPLIEGSRPNHKLRVLINRLENILNGYHE-----NSGIETTLKELIKILRDGRLPYSEWDSQISTVRNRLPRQLNEGLGNLVKKSVSFPAKELHKLMKR--------------------------------YLEENTNDHVVYVALQPLLKISERYSEGLANHECEIFLKLIKKYYAVEKIFENHDIHEERNLLNLRRKDLTNLKKILCISLSHANVVAKNKLVTAILHEYEPLCQDSSKMSLKFRAVIHDLASLESKWAKEVAVKARSVLLRGIFPPIKKRKEHIKTLLQLHIKDTGAENIHSRNIYSCMRDFGNLIHSNLIQLQDLFFFFGHQDTALSSIASEIYARYAYGNYQLKSIKIHKGAP-DLLMSWQFSSLRNYLVN-------------------------SDGESDEFTKLSKPPS-----TSGKSSANSFGLLVNMRALESLEKTLDEVYEQIHIPEER------------------------------------------LSSGENSLIVNILSPIRYRSEND-LIKTLKIKLHENERGLSKLKVNRITFAFIAAN--------------APAVKFYSFDG-TTYDEISQIRNMDPSYEAPLELGKMSNYKIRSLPTYDSSIRIFEGISKFTP----LDKRFFVRKIINSFMYNDQKTTEENLKAEINAQVVYMLEHLGAVDIS----NSDLNHIFLSFNTVLNIPVHRLEEIVSTILKTHETRLFQERITDVEICISVECLETKKPAPLRLLISNKSGYVVKIETYYEKIG-KNGNLILEPCSE-QSHYSQKSLSLPYSVKDWLQPKRYKAQFMGTTYVYDFPGLFHQAAIQQWKR-----YFPKHKLNDSFFSWVELIEQN-GNLIKVNREPGLNNIGMVAFEIMVQTPEYPEGRNMIVISNDITYNIGSFGPREDLFFDRVTNYARERGIPRIYLAANSGAKLGIAEELIPLFRVAWNDPSDPTKGFQYLYLAPKDMQLLKDSGKGNSVVVEHKMVYGEERYIIKAIVGFEEGLGVECLQGSGLIAGATSKAYRDIFTITAVTCRSVGIGSYLVRLGQRTIQVEDKPIILTGASAINKVLGTDIYTSNLQIGGTQIMYKNGIAHLTASNDMKAIEKIMTWLSYVPAKRDMSPPLLETMDRWDRDVDFKPAKQVPYEARWLIEGKWDS--NNNFQSGLFDKDSFFETLSGWAKGVIVGRARLGGIPVGVIAVETKTIEEIIPADPANLDSSEFSVKEAGQVWYPNSAFKTAQTINDFNYGEQLPLIILANWRGFSGGQRDMYNEVLKYGSFIVDALVDYKQPILIYIPPFGELRGGSWVVIDPTINPEQMEMYADVESRGGVLEPDGVVSIKYRKEKMIETMIRLDSTYGHLRRTLTEKKLSLE--KQNDLTKRLKIRERQLIPIYNQISIQFADLHDRSTRMLVKGVIRNELEWKKSRRFLYWRLRRRLNEGQVIKRLQKKT---CDNKTKMKYDDLLKIVQSWYNDLDVNDDRAVVEFIERNSK-------KIDKNIEEFEISLLIDELKKKFEDR---RGNIVLEELTRLVDSKRKR--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . .. : :** ** :*..:*********** *****:*:** *.:*: *:****.**:**:**:***:***:** ****.*******:::*:*:* : *:************* ***** . : *:**. .** :****::*::***: :* :****: : . :.:. ::: :* . : .* .: :*:*:::************:.: ::* *:**. * ****:*:*::. :******:******. ::*******:*******:****. :: *: **: *: *.: ************:. :. :.************* ***::.*****:****.**:*:. :.*** ::* * * : : *. * . ** *:.*****:*:******:*.::******..********. *.:*.*:****** *: *::*::* .*:*:*:*::****:*:*.:***: ****. * * *.*.*** ** ..:.:: : * *.::.*: * ..: *.:**: . * . . *::* . :* .:.::.. :.: :* . *::.::*... :*:* * .:*.* *::: *: :..:* .:* * :*: : **:.*** : * .* ** .. ***:*:*** *.* * : :::.* ::.* ::. : **.** . : : .: :: . * : : *: :. :. :: **. ** * :. :::: .*:* ::: : . : :. * :: .: *:.. : . .:: *.:::: ::* .* . . .*:::* ** *: * :: : :*.. :: :: :**::* ** ** ::.. * .. :: :: : :*:.*. .**:::*.:*: . *. . *:::::::: :. * : .:: .** *: :: * ** * : .: : *:*.* .* *:*..:: : : :** : . . * :. : :: : .:: : : *:.: :: : : :.:: * . :.*:** *:::* . : * *:::*: ***.:* .: : ::* . :::: * ::. * ***:* **. :::: * *: * : :: ::.* .. .:* *****.* ..: : ::** * :: : .**:: *: :.*: : :. .:** ::*.*** :.*. * * .. : :.. .: *. :. ** .** ** **::** ****:**.* :*:* : * ...: : : . .:*:.::* ** *: ***.:.: . : *** **: :** **:*. ***** ** :: :.:: ** :*:**::.****::*::**: :*::** *. :* **::****:.:* : *** **.** : ::* : .:* * *: :* *** :* ** . .*: ****::***:*:******.**:::. :**** .*:**:** .:*:** *:** ***. **::* . *:..: .:: ***::* *: . * :* ::* *:: **:.**:: *: . . : .*:** .*: * : **: *:.*******:* **:****:::* :*********. :::*****:*:*::** *.:.**. * ***:::********* :***::::*:*::***.* :*:::*:** .*****:*.*:*. ** :* *** ::**.***.:* *.**::.:.::::: *:*.. * * . . :: ::* * *: :*: ::::*.*:** . :* * * : : * :* ::****** * * :.: : : : :. : :.:. :..: *.: : .*: . . :. : .: : : : :: ", "identical_positions": 690, "similar_positions": 716, "identity": "26.67%" }, { "cls_id": "homologset.agr.SGD:S000004821", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17256-1", "uniprot_id": "KIME_RAT", "id": "P17256-1", "name": "Mevalonate kinase", "aln": "MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALN-LRTFLVLRPQSN-GKVSLNLPNVGIKQVWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNE-----GLSLLAFLYLYLAICRKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQ----GKMSS-----LKRLPALQILLTNTKVPRSTKALVAGVRSRLIK-FPEIMAPLLTSIDAISLECERVLGEMAAAP---------VPEQYLVLEELMDMNQHHLNALGVGHASLDQLCQVTAAHGLHS-KLTGAGGGGCGITLLKPGLERAKVEAAKQALTG-CGFDCWETSIGAPGVSMHSATSIEDPVRQALG-L----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R008-1", "uniprot_id": "KIME_MOUSE", "id": "Q9R008-1", "name": "Mevalonate kinase", "aln": "MLSEALLVSAPGKVILHGEHAVVHGKVALAAALN-LRTFLLLRPQSN-GKVSVNLPNIGIKQVWDVGMLQRLDTSFLEQGDVSVPTLEQLEKLKKMGDLPRDRAGNE-----GMALLAFLYLYLAICRKQRTLPSLDMVVWSELPPGAGLGSSAAYSVCLAAALLTACEEVSNPLKDGVSVSRWPEEDLKSINKWAFEGERVIHGNPSGVDNAVSTWGGALRFQQ----GTMSS-----LKSLPSLQILLTNTKVPRSTKALVAAVRSRLTK-FPEIVAPLLTSIDAISLECERVLGEMVAAP---------VPEQYLVLEELIDMNQHHLNALGVGHNSLDQLCQVTAAHGLHS-KLTGAGGGGCGITLLKPGLEQATVEAAKQALTS-CGFDCWETSIGAPGVSTHSAAAVGDPVRQALG-L----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03426-1", "uniprot_id": "KIME_HUMAN", "id": "Q03426-1", "name": "Mevalonate kinase", "aln": "MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLN-LRTFLRLQPHSN-GKVDLSLPNIGIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTE-----RLAVLAFLYLYLSICRKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQ----GKISS-----LKRSPALQILLTNTKVPRNTRALVAGVRNRLLK-FPEIVAPLLTSIDAISLECERVLGEMGEAP---------APEQYLVLEELIDMNQHHLNALGVGHASLDQLCQVTRARGLHS-KLTGAGGGGCGITLLKPGLEQPEVEATKQALTS-CGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07277-1", "uniprot_id": "ERG12_YEAST", "id": "P07277-1", "name": "Mevalonate kinase", "aln": "-MSLPFLTSAPGKVIIFGEHSAVYNKPAVAASVSALRTYLLISESSAPDTIELDFPDISFNHKWSINDFNAITEDQVNSQKLAKAQQATDGLSQELVSLLDPLLAQLSESFHYHAAFCFLYMFVCLCP---HAKNIKFSLKSTLPIGAGLGSSASISVSLALAMAYLGGLIG-----SNDLEKLSENDKHIVNQWAFIGEKCIHGTPSGIDNAVATYGNALLFEKDSHNGTINTNNFKFLDDFPAIPMILTYTRIPRSTKDLVARVRVLVTEKFPEVMKPILDAMGECALQGLEIMTKLSKCKGTDDEAVETNNELYEQLLELIRINHGLLVSIGVSHPGLELIKNLSDDLRIGSTKLTGAGGGGCSLTLLRRDITQEQIDSFKKKLQDDFSYETFETDLGGTGCCLLSAKNLNKDLKIKSLVFQLFENKTTTKQQIDDLLLPGNTNLPWTS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :*.*******:.***:.*:.* *:*.::. ***:* : * ..:.:.:*::.::: *.: :: : . ::. .:. . ::: .* : :.***:::.:* .:.: : * ** ********: **.:* *: : : .::* . :*:**: **: ***.***:**:*:*:*.** :.: *.:.: *. *:: ::** *::**.*: *** ** : : ***:: *:* ::. :*: .:: :: . * * * **: :*: * ::**.* .*: : ::: : * **********.:***: .: : ::: *: * . .:: **.:*..* . ** : . :: : ", "identical_positions": 115, "similar_positions": 148, "identity": "25.44%" }, { "cls_id": "homologset.agr.SGD:S000004822", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80UY1-1", "uniprot_id": "CARME_MOUSE", "id": "Q80UY1-1", "name": "Protein-L-histidine N-pros-methyltransferase CARNMT1", "aln": "-----------------MQRRQRAPPASQPAQD-----GGRSEDVEVQFSAGRLGSAAP----AGPPARGTAEDEERLEREHFWK-----------VINAFRYYGTSMHERVNRTERQFRSLPENQQKLLPQFPLHLDKIRKCIDHNQEILLTIVNDCIHMFENKEYGEDAN-GKIMPASTF-DMD-------------------------KLKSTLKQFVRDWSETGKAERDACYKPIIKEIIKNFPKERWDPSKVNILVPGAGLGRLAWEVAMLG--YACQGNEWSFFMLFSSNFVLNRCSEINKYKLYPWIHQFSNNRRSADQIRPILFPDVDPHSLPPGSNFSMTAGDFQEIYSECNAWDCIATC--FFIDTAHNVIDYIDTIWRILK--PGGIWINLGPLLYHFENLANELSIELSYEDIKNVVLQYGFQLEVEKESVLSTYTVNDLSMMKYYYECVLFVVRKPQ------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N4J0-1", "uniprot_id": "CARME_HUMAN", "id": "Q8N4J0-1", "name": "Protein-L-histidine N-pros-methyltransferase CARNMT1", "aln": "-----------------MQRRRRPPPPTSRLPEGCGGGGGGSEEVEVQFSAGRWGSAAAVSAAAAAATRSTEEEEERLEREHFWK-----------IINAFRYYGTSMHERVNRTERQFRSLPANQQKLLPQFLLHLDKIRKCIDHNQEILLTIVNDCIHMFENKEYGEDGN-GKIMPASTF-DMD-------------------------KLKSTLKQFVRDWSETGKAERDACYQPIIKEILKNFPKERWDPSKVNILVPGAGLGRLAWEIAMLG--YACQGNEWSFFMLFSSNFVLNRCSEINKYKLYPWIHQFSNNRRSADQIRPIFFPDVDPHSLPPGSNFSMTAGDFQEIYSECNTWDCIATC--FFIDTAHNVIDYIDTIWKILK--PGGIWINLGPLLYHFENLANELSIELSYEDIKNVVLQYGFKVEVEKESVLSTYTVNDLSMMKYYYECVLFVVRKPQ------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BJ21-1", "uniprot_id": "A0A8M2BJ21_DANRE", "id": "A0A8M2BJ21-1", "name": "Carnosine N-methyltransferase", "aln": "-----------------MANSSSETVAAS------------KPEVFHNYRD---------------RNRCSPEEETRLEKQHFWN-----------VINAFKYYRTHVHERVNRAERQFRCLPDHHQQLLTNFLPHLNKLRYCIDQNQEVLQAVVHNCLHMFENMEYGQDVDPRKVRPSSTF-DMD-------------------------KLKSTIKQFVRDWSEAGKAERDSCYKPIIDEIQRLFPPDQCDVSQVRVLVPGAGLGRLAWEIAHLG--YSCQGNEWSFFMLFSSNFVLNRCDKENALTLYPWIHQFSNNKASSDQTRPVSFPDVNPQSLPEDSDFSMVAGDFQEVYNDPEMWDCVATC--FFIDTAHNVLDYIETIWNILK--PGGVWLNLGPLLYHYENMANELSIELSYEDIKAVAMKYGFVLELERESVPSTYTENDRSMLKYLYDSVFFIVRKPAKQLINGDKALKDSQTEDSLHTKNST-----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7X6-2", "uniprot_id": "CARME_DROME", "id": "Q9I7X6-2", "name": "Carnosine N-methyltransferase unmet", "aln": "-----------------MSSMDCATFPMH-------------PKMDEQLAR----------------TFVINEEE---EEKHIQK-----------VQNAFLYYGPYACQRLKRSMDYLNSLSGEDQIMLAKYRGHLECVRTCIDRNQAVIREILRGRVLYPTDEATGDPSEFDEPPPNVRHGDMDQIDIPFDEA--------DVEPLKILKAQSTLKLIARDWSTEGALEREQSYKPIIDSIVAYFKHSDFELKDIKILVPGAGLGRLTYELACLG--YSCEGNEFSYFMLIASNFVLNLCDNENKYVLYPWVHQYVNNLRREDQVAPVRFPDVCPLKNPPKGHFEIAAGDFLEVYKTPNAYNCVATC--FFIDCANNVIDFIRTIYKILV--PGGIWVNLGPLLYHFSDVSGQNSIEPAFEDLCIIMESVGFVIEKSRTGIRTKYAQNPSSMKQSEYQSLFWVCRKPDLFEEQRGKRKASREPHDLIVREDSEEEGEQQPERNETEEKQQLKPLATANCETEIKEQPS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03648-1", "uniprot_id": "YM59_YEAST", "id": "Q03648-1", "name": "Uncharacterized protein YMR209C", "aln": "MVSSLASNIILALVVVLMTLLRQNKPLQRWFVSYVEKLLSRKSNLAQKVSVLSPSLKLVD------VEKSISADQSNLSKINYQIPTLPDLTGNLIRLHEYRARGEGYNGLLFRRARQLNGISEDQLQKLG-YFTKLMKNNEGIRENARVIDKIIEFTLGKLIHSNEHDEEFTEEIEKICAEHGYKIKDGHLIQLNPDFVFPIVSSRGSQSVVHEALAHLCRDFSSYYSVERDPLQNFIISRINHHVISAGDMKEKILIVTPGAGVGGLSHTLATTFPKIQVDSIELSALMYICNLFALEYKHDVK---IRPFVQQYSCQTVFDNQLRSLS---ADLSKVGHRSNLDPLWGDFTRYSPISKDYDKIIICSAYFIDTAENMFEYLSSIEALKKYCKELHWVNVGPLKYGTKPLVQFTGDELSRLRKIRGWKDLVEEYEVDSSKGLNGYLTDYESMYQGYYGLLKFHSVFES------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: : :: .. : : : : * :. :. .. * : :* . * .* :: ::. : . : : . . :.:: : **:* **: : **. * . ..: ::.****:* *: :* :. * * :* :.. *.*: . : : *:::*: : :* .: . . ..:. *** . : :: : * :*** *.*::::: :* : *:*:*** * . : . * : . * . . * : ** : * : : ", "identical_positions": 51, "similar_positions": 103, "identity": "9.62%" }, { "cls_id": "homologset.agr.SGD:S000004823", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZC8-1", "uniprot_id": "ABHD1_MOUSE", "id": "Q9QZC8-1", "name": "Protein ABHD1", "aln": "-------------------------------------------------------------MEYPYTTK-MLSSSLSPQN------------GTWSDTISLLLALGVAL--YLGYYWACVPQRPRLVAG-PQFLAFLEQHCPVTVETFYP-TLWCFEGRLQTIFRVLLQSQ--PVVPYRSEVLQTPD-----GGQFLLDWAEQPNST--HYPDPTTQPIVLLLPGISGSSQEPYILHLVNQAL-KDGYRAVVFNNRGCR-GEELLTHRAYCASNTEDLETVVKHIKRRYSQ-APLLAVGISFGGILVLNYLAQTGKAGG--LVAGLTMSACWDSFETVDS-LETPLNSLLFNQPLTAGLCRLVARNRKPIEKV----------LDVDFAIKARTIRQLDERYTSVAFGYKD-CAAYYQAASPRTKVDAIHTPVLCLNAADDPFSP--VHAFPLQAAQKSPYVALLITARGGHIGFLEG--LMP-WQHCYMN--RVLHQ-YARAIFQ-------------------HSVGLPDLGVLTP-EDGKS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5RK23-1", "uniprot_id": "ABHD1_RAT", "id": "Q5RK23-1", "name": "Protein ABHD1", "aln": "-------------------------------------------------------------MEYLHITK-MLSSSLSPQN------------GTWSDAISLLLALGIAL--YLGYYWACVPQRPRLVAG-PQFLAFLEQHCPVTVETFYP-TLWCFEGRLQTIFRVLLQSQ--PVIPYRSEVLQTPD-----GGQFLLDWAEQPYSS--HCPDPTTQPIVLLLPGISGSSQEPYILHLVDQAL-KDGYRAVVFNNRGCR-GEELLTHRAYCASNTEDLETVVKHIKHRYSR-APLLAVGISFGGILVLNYLARTGKAGG--LVAGLTMSACWDSFETVDS-LETPLNSLLFNQPLTAGLCRLVARNRKSIEKV----------LDVDFAIKARTIRQLDERYTSVAFGYKD-CAAYYHASSPRTKVDAICTPVLCLNAADDPFSP--VQALPLQAAQKSPYVALLITARGGHIGFLEG--LLP-WQHCYMN--RVLHQ-YARAVFQ-------------------HSVGLPGLGALTP-EDGKS----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96SE0-1", "uniprot_id": "ABHD1_HUMAN", "id": "Q96SE0-1", "name": "Protein ABHD1", "aln": "----------------------------------------------------------------------MLSSFLSPQN------------GTWADTFSLLLALAVAL--YLGYYWACVLQRPRLVAG-PQFLAFLEPHCSITTETFYP-TLWCFEGRLQSIFQVLLQSQ--PLVLYQSDILQTPD-----GGQLLLDWAKQPDSS--QDPDPTTQPIVLLLPGITGSSQETYVLHLVNQAL-RDGYQAVVFNNRGCR-GEELRTHRAFCASNTEDLETVVNHIKHRYPQ-APLLAVGISFGGILVLNHLAQARQAAG--LVAALTLSACWDSFETTRS-LETPLNSLLFNQPLTAGLCQLVERNRKVIEKV----------VDIDFVLQARTIRQFDERYTSVAFGYQD-CVTYYKAASPRTKIDAIRIPVLYLSAADDPFSP--VCALPIQAAQHSPYVALLITARGGHIGFLEG--LLP-WQHWYMS--RLLHQ-YAKAIFQ-------------------DPEGLPDLRALLPSEDRNS----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91ZH7-1", "uniprot_id": "ABHD3_MOUSE", "id": "Q91ZH7-1", "name": "Phospholipase ABHD3", "aln": "--------------------------------------------------------MQRLAMDLRVLSR-ELALYLEHQVRV----------GFFGSGVGLSLILGFSVA-YACYYLSSIAKKPQLVIGGESFSRFLQDHCPVVTETYYP-TVWCWESRGQTLLRPFITSK--PPVQYRNELIKTAD-----GGQISLDWFDNNNSA--YYVDASTRPTILLLPGLTGTSKESYILHMIHLSE-ELGYRCVVFNNRGVA-GESLLTPRTYCCANTEDLEAVVHHVHSLYPG-APFLAAGVSMGGMLLLNYLGKIGSKTP--LMAAATFSVGWNTFACSES-LERPLNWLLFNYYLTTCLQSSVKKHRHMFVEQ----------IDMDQVMKAKSIREFDKRFTAVMFGYRT-LDDYYTDASPNRRLKSVGIPVLCLNATDDVFSP--SHAIPIETAKQNPNVALVLTAYGGHIGFLEG--IWP-RQCTYMD--RVFKQ-FVQAMVE-------------------HGHELSNM---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1Z7Q7-1", "uniprot_id": "A1Z7Q7_DROME", "id": "A1Z7Q7-1", "name": "", "aln": "MLCALVRGPTTGHKLVLYRSVAELLGPVHDIRCLSAGRGVYQRQSRSQSQSQSQLQNPAHRPDLLSLSRPALSSKLSVRSLHSENDAMFYSMYAYLSNLPRLHVLGMAVVAYVVYYLIQVVKRPIIACSDGPFKQYLIRKVPTLENKYWP-TFWCVESRAQTVLASLLRSKSLPRVNYRREILSLKD-----GGEVALDWMEEG--------CDQSAPCILILPGLTGESQAEYIKCLVFAAQ-QAGMRVVVFNNRGLG-GIELKTPRLYCAANCEDLCEVVQHVRRTLPEKCKLGATGISMGGLILGNYLARKSDEARSFLSAAKIISVPWDVHKGSAS-IEKPVINSLLGRHLAGSLCRTLRNHLDIYRDIYQD-----SDIDIQRILRCKTIKEFDALFTAKQFGYAH-VNDYYSDATLHNKLDHISVPLLCLSAADDPFQP--LDAIPIKAANQCTHVAIVITARGGHIGFLEG--WWPSTKDQYMG--RLFTEYFTKALFDEDGEFQHTANKMHERFLAKQTVALASSSPVLFAKKIDADQLDHKVKLM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9QXM0-1", "uniprot_id": "ABHD2_MOUSE", "id": "Q9QXM0-1", "name": "Monoacylglycerol lipase ABHD2", "aln": "-----------------------------------------------------------------------MNAMLETPELP-----------AVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPDLYFQDSGLSRFLLKSCPLLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITMSD-----GATSTFDLFEPLA-----EHCVGDDITMVICPGIANHSEKQYIRTFVDYAQ-KNGYRCAVLNHLGALPNIELTSPRMFTYGCTWEFGAMVNYIKRTYPQ-TQLVVVGFSLGGNIVCKYLGETQ-ANQEKVLCCVSVCQGYSALRAQETFMQWDQCRRFYNFLMADNMKKIILSHRQALFGDHVKKPQSLEDTDLSRLYTATSLMQIDDNVMRKFHGYNS-LKEYYEEESCMRYLHRIYVPLMLVNAADDPLVHESLLTIPKSLSEKRENVMFVLPLHGGHLGFFEGSVLFP-EPLTWMD--KLVVE-YANAICQWE----------------RNKSQCSDTEQMEAELE-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A7W1-1", "uniprot_id": "D4A7W1_RAT", "id": "D4A7W1-1", "name": "Monoacylglycerol lipase ABHD2", "aln": "-----------------------------------------------------------------------MNAMLETPELP-----------AVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPDLYFQDSGLSRFLLKSCPLLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITMSD-----GATSTFDLFEPLA-----EHCVGDDVTMVICPGIANHSEKQYIRTFVDYAQ-KNGYRCAVLNHLGALPNIELTSPRMFTYGCTWEFGAMVNYIKKTYPQ-TQLVVVGFSLGGNIVCKYLGETQ-ANQEKVLCCVSVCQGYSALRAQETFMQWDQCRRFYNFLMADNMKKIILSHRQALFGDHVKKPQSLEDTDLSRLYTATSLMQIDDNVMRKFHGYNS-LKEYYEEESCMRYLHRIYVPLMLVNAADDPLVHESLLTIPKSLSEKRENVMFVLPLHGGHLGFFEGSVLFP-EPLTWMD--KLVVE-YANAICQWE----------------RNKSQCSDTEQMEAELE-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08910-1", "uniprot_id": "ABHD2_HUMAN", "id": "P08910-1", "name": "Monoacylglycerol lipase ABHD2", "aln": "-----------------------------------------------------------------------MNAMLETPELP-----------AVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPDLYFQDSGLSRFLLKSCPLLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITMSD-----GATSTFDLFEPLA-----EHCVGDDITMVICPGIANHSEKQYIRTFVDYAQ-KNGYRCAVLNHLGALPNIELTSPRMFTYGCTWEFGAMVNYIKKTYPL-TQLVVVGFSLGGNIVCKYLGETQ-ANQEKVLCCVSVCQGYSALRAQETFMQWDQCRRFYNFLMADNMKKIILSHRQALFGDHVKKPQSLEDTDLSRLYTATSLMQIDDNVMRKFHGYNS-LKEYYEEESCMRYLHRIYVPLMLVNAADDPLVHESLLTIPKSLSEKRENVMFVLPLHGGHLGFFEGSVLFP-EPLTWMD--KLVVE-YANAICQWE----------------RNKLQCSDTEQVEADLE-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q802V6-1", "uniprot_id": "ABH2A_DANRE", "id": "Q802V6-1", "name": "Monoacylglycerol lipase ABHD2", "aln": "------------------------------------------------------------------MNTHESEVYTVAPEMP-----------AMFDGMKLAAVATVLYVIVRCLNLKSPTAPPDLTFQDTTLNHFLLKSCPILTKEYIPPLLWGKSGHLQTALYGKLGRVSSPHPFGLRKYLPMQD-----GATATFDLFEPLA-----DHQSGEDVTMVICPGIGNHSEKHYIRTFVDHSQ-KQGYRCAVLNHLGALPNIELTSPRMFTYGCTWEFAAMVGFIKKTYPQ-SKLIVVGFSLGGNIVCKFLGENR-TNQERVLCCVSVCQGYSALRAQETFLQWDQCRRFYNFLMADNMKKIILSHRGVLFGVG----SKMVDSELSRLYTATSLMQIDDNIMRKFHGHNS-LKEYYEKESCVHYIHNINVPLLLVNSVDDPLVHNSLLTIPRTLAEKKENVVFALTLHGGHLGFFEGAVLFP-QPLTWMD--KVIVD-YATAMCQWE----------------KQKPPCQSKDAQSNQTTCQENTS-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05AK6-1", "uniprot_id": "ABH2B_DANRE", "id": "Q05AK6-1", "name": "Monoacylglycerol lipase ABHD2", "aln": "-----------------------------------------------------------------MSAQLEADVRTMSPEMP-----------AMFDGMKLAAVAAVLYVIVRSLNLKCPTAAADITCQDTLLNHYLLKSCPVLTKEYIPPLLWGKSGHLQTALYGKIGRVKSPKPCGLRKFLPMQD-----GATATFDLFEPQG-----VHSTGDDITMVICPGIGNHSEKHYIRTFVDYSQ-KQGYRCAVLNHLGALPNIELTSPRMFTYGCTWEFSAMVGFIKRTFPQ-TQLIVVGFSLGGNIACKYLGENP-ANQERVLCCVSVCQGYSALRAQETFLQWDQCRRLYNFLMADNMKKIILSHRGSLFGMNS---SRMEFADLSRLYTATSLMQIDDNIMRKFHGHNS-LKEYYEKESCVHYIHNISVPLLLVNSSDDPLVHQSLLTIPRTLAEKKQNVIFALTLHGGHLGFFEGAVLFP-QPLSWMD--KVIVS-YANAVCQWE----------------KHKPQCHQQKE-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24093-1", "uniprot_id": "ABHD2_DROME", "id": "Q24093-1", "name": "Abhydrolase domain-containing protein 2", "aln": "--------------------------------------------------------------------------------MS-----------TAF----LTLIAVIVCILFRILNVHSQPLKPSVWCLDAHFLDCLYKIAPVLREPYIPPRLWGFSGHVQTVLHSIVGRVRCPWPLGERVYMSLKD-----GSTLTYDLYQPLN-----EQE--DDITVAICPGIANSSESVYIRTFVHLAQ-CNGYRCAVLNHIGALRSVQVTSTRIFTYGHTEDFAAMVEHLHQKYRQ-SRIVAVGFSLGGNLVTKYMGEDQKTKPDKVIGGISICQGYNAVEGTKWLLNWQNFRRFYLYIMTENVKSIILRHRHILLSDEVKARHNLNERE---IIAAATLPELDEAYTRRVYNFPS-TQELYKWSSSLFYFDTIKKPMIFINAKDDPLIPEDLLHPIKEYATTRQNTAYVEVAHGGHLGFYEGGFLYP-NPVTWLD--RTLVA-MVGSLVMMH----------------EVGKVAP-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q5F2F2-1", "uniprot_id": "ABH15_MOUSE", "id": "Q5F2F2-1", "name": "Protein ABHD15", "aln": "-------------------------------------------MPPWAAALALLLAALALLLLR------PWKRAVGARTS-------------VRDHEE-QEVASGGPADQFSDRREALPGGCSLICKPSALAQCLLRALRRSAALEPSPRSWLSGPHLQTFCHFILPVG--PGPELAREYLQLAD-----DGLVALDWVIGPCARGRRVTNPGSLPPVLLVIPNAWGRLTRNVLGLCLLAL-ERGYYPVIFHRRGHH-GCPLVSPRLQPFGDPSDLKEAVTYIRFRHPA-APLFAVSEGSGSALLLSYLGECG--SSSYVTGAACISPVLRCREWFEAGLPWPYERGFLLHQKIS-----LSRYASALEDT----------VDTGKLFRSGSLREFEETLFCHTKSCPISWDTYWDLNDPLRDVDEAAVPVLCICSADDPVCGPPEHTLPAELFHSNPYFFLLLSHHGGHCGFLRPEPLPAWSHEVILESFRALTEFFRMEERMKG-----LSRRRTSFLGGRRRWGGLQKREVSPSSNLEEIFNWKRSYTR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z8B6-1", "uniprot_id": "D3Z8B6_RAT", "id": "D3Z8B6-1", "name": "Protein ABHD15", "aln": "-------------------------------------------MPPWPAALALLLAALALLLLR------PWKRAVGARTS-------------VRDHEE-QEVVSGGPADHFSDRREPLPGGCSLICKPSALAQCLLRALRRSAALEPSPRSWLSGPHLQTFCHFILPVG--PDPELAREYLQLAD-----DGLVALDWVIGPCARGRRVTNPGSLPPVLLVIPNAWGRLTRNVLGLCLLAL-EHGYYPVIFHRRGHH-GCPLVSPRLQPFGDPSDLKEAVTYIRFRHPA-APLFAVSEGSGSALLLSYLGECG--SSSYVTGAACISPVLRCREWFEAGLPWPYERGFLLYQKIA-----LSRYASALEDT----------VDTGKLFKSSSLREFEETLFCHTKSLPISWDTYWDLNDPLRDVDEAAVPVLCICSADDPVCGPPDRTLPAELFHTNPYFFLLLSSHGGHCGFLRPEPLPAWSHEIILESFRALTEFFRMEERMKG-----LSRRRTSFLGGRRRWGGLQKREVSPSSNLEEIFDWKRSYTR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UXT9-1", "uniprot_id": "ABH15_HUMAN", "id": "Q6UXT9-1", "name": "Protein ABHD15", "aln": "-------------------------------------------MPPWGAALALILAVLALLGLLGPRLRGPWGRAVGERTLP-----------GAQDRDDGEEADGGGPADQFSDGREPLPGGCSLVCKPSALAQCLLRALRRSEALEAGPRSWFSGPHLQTLCHFVLPVA--PGPELAREYLQLAD-----DGLVALDWVVGPCVRGRRITSAGGLPAVLLVIPNAWGRLTRNVLGLCLLAL-ERGYYPVIFHRRGHH-GCPLVSPRLQPFGDPSDLKEAVTYIRFRHPA-APLFAVSEGSGSALLLSYLGECG--SSSYVTGAACISPVLRCREWFEAGLPWPYERGFLLHQKIA-----LSRYATALEDT----------VDTSRLFRSRSLREFEEALFCHTKSFPISWDTYWDRNDPLRDVDEAAVPVLCICSADDPVCGPPDHTLTTELFHSNPYFFLLLSRHGGHCGFLRQEPLPAWSHEVILESFRALTEFFRTEERIKG-----LSRHRASFLGGRRRGGALQRREVSSSSNLEEIFNWKRSYTR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03649-1", "uniprot_id": "MGL2_YEAST", "id": "Q03649-1", "name": "Monoacylglycerol lipase", "aln": "------------------------------------------------------MRLKELLPNFLIVHQEVPEDPIAFKSTD----------KRENENKEITIPELIDTKVPELADGATDTLYGLLVNGHLQTAYGSFRHFDNIYKVQYKRMIIKYPHGGEGTVDFAVNGRSTKRRKVEKEYVPTSQPVFNGNLKRRYSYYSPDDPK---LNSDDAKPMLIILHGLTGGSRESYVRAIVHEITTKYDFEACVFNARGCC-YSAITTPLLYNGGWTNDIRYCVNDLRKRFPN-RKFYMMGFSLGASIMTNYLGEES--DRTKIECAISVSNPFDLYNSAYFINSTPMGSRFYSPALGHNLLRMVRNHLSTLEENPD-----FKDVIEKHLKKIRTVRQFDNLLTGPMFGYKN-AEEYYKNASSYKRIPGIRTPFIALHAQDDPIVG---GDLPIDQIKSNPYTLLLETSTGGHVGWFKDRSGRRWYAEPLCRFLKIFHDEITVKGLKPD----------------LENVQLPDPNCEPIATTFRAN---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : : . . : : : : . ::: * : : . :: * :: : . . *. : ..:.. : .. : : :: ::: . : . *.: : : ** . *** *: . : . ", "identical_positions": 10, "similar_positions": 54, "identity": "1.81%" }, { "cls_id": "homologset.agr.SGD:S000004824", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2YDW2-1", "uniprot_id": "MSTO1_MOUSE", "id": "Q2YDW2-1", "name": "Protein misato homolog 1", "aln": "--------------MAGGAREVLTLQLGHFAGFVGAHWWNQQDAALGRMAEDEESPGELCP--DVLYRTG-RTLHGQETYTPRLILMDLKGSLNTLKEEGNLYR--DRQLEAAVAWQGKLSTHREDAHPKNPNLQGL--LSAEGVRSSDGAWRAKLIQNIQNGKENS----------------------IKVWSDFLRVHLHPRSICVIHKYHHDGETGRLEAFGQGESVLKEPRYLEELEDRLHFYVEECDYLQGFQLLCDLHDGFSGVGAKTAELLQDEYAGRGVLTWGLLP--GPYSLGEP-QKNIYRLLNTAFGLVHLTGYSSFVCPLSLGGNLGLRPKP-PVNFPSLHYDATLPFHCSAILATALDTVTVPYRLRSSMVTMAHLADVLSFSGKKVVTAEAIIPFPLVRGQSLPDILTQLGEATPWTSLSACGDSAGHR-CFAQSVVLRGIDRASHTS-KLNPGTPLPSALHACASGEEVLAQYLQQQHPRVLSSSHLLLTPCKVAPPYP-HFFS-SFSQKGLAMDS----TPKGAAVQSIPVFGALRSTSSLHRTLGDLAEELSRLDLRRWA-SFMDAGVEQDDMEEMLHELHRLAQCYQ----------------EGDSLSN-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AIT8-1", "uniprot_id": "A0A8I6AIT8_RAT", "id": "A0A8I6AIT8-1", "name": "", "aln": "RGPRLPWSAQELRRHGGRGPRGAHAAVGTFRGFRRGALVEPAGCCVGTHDRGRRVARRAVP--GRLVSKWPDTAWPGNLYTS--THPHGPQSLNTLKEEGSLYR--DRQLEAAIAWQGKLTTHREEANSKNPNLQDL--LSAEGVLSSDGALRAKLIQ---NGKENS----------------------IKVWSDFLRVHLHPRSICVIQKYNHDGETGRLEAFGQGESVLKEPRYLEELEDRLHFYVEECDYLQGFQILCDLHDGFSGVGAKTAELLQDEYSGRGVLTWGLLP--GPYSLGEP-QKNIYRLLNTAFGLVHLAGYSSFVCPLSLGGNLGLRPKP-PVNFPYLHYDATLPFHCSAILATALDTVTVPYRLRSSTVSMAHLADVLSFSGKKVVTAEAIIPFPLVRGQSLPDILMQLGEATPWTSLSACGDSAGHR-CFAQSVVLRGIDRASHTS-KLNPGTPLPSTLHACASGEEVLAQYLEQQHPRVLSSSYLLLTPCKMAPPYP-HFFS-SFSQKGLAMDG----APKGAAVQSIPVFGALRSTSSLQRTLRDLGDELARLDLRRWA-SFMDAGVEQDDMEELLQELHSLAHLDSGPPSWQGQEPSLAASGHSDSYNRQQLD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BUK6-1", "uniprot_id": "MSTO1_HUMAN", "id": "Q9BUK6-1", "name": "Protein misato homolog 1", "aln": "--------------MAGGAREVLTLQLGHFAGFVGAHWWNQQDAALGRATDSKEPPGELCP--DVLYRTG-RTLHGQETYTPRLILMDLKGSLSSLKEEGGLYR--DKQLDAAIAWQGKLTTHKEELYPKNPYLQDF--LSAEGVLSSDGVWRVKSIP---NGKGSSPLPTAT-----TPKPLIPTEASIRVWSDFLRVHLHPRSICMIQKYNHDGEAGRLEAFGQGESVLKEPKYQEELEDRLHFYVEECDYLQGFQILCDLHDGFSGVGAKAAELLQDEYSGRGIITWGLLP--GPYHRGEA-QRNIYRLLNTAFGLVHLTAHSSLVCPLSLGGSLGLRPEP-PVSFPYLHYDATLPFHCSAILATALDTVTVPYRLCSSPVSMVHLADMLSFCGKKVVTAGAIIPFPLAPGQSLPDSLMQFGGATPWTPLSACGEPSGTR-CFAQSVVLRGIDRACHTS-QLTPGTPPPSALHACTTGEEILAQYLQQQQPGVMSSSHLLLTPCRVAPPYP-HLFS-SCSPPGMVLDG----SPKGAAVESIPVFGALCSSSSLHQTLEALARDLTKLDLRRWA-SFMDAGVEHDDVAELLQELQSLAQCYQ----------------GGDSLVD-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1L908-1", "uniprot_id": "MSTO1_DANRE", "id": "Q1L908-1", "name": "Protein misato homolog 1", "aln": "--------------MSGACREVVTLQLGHYSNFIGTHWWNLQDAGL--VYDADVPAGELQS--DVLFREG-LTLAGHVTYTPRLIAIDLKGSLQTLRKEGSLYD--TENENSAFTWDGQIMTHQESPPSKNSFLQELDNLDTGGVLAESDFNHLTSSVDNCSVPGASVAVETINSSLERIQKSYRLEGSVRVWSDFLRLHLHPRTISVINQYNHDGESERLEVFGQGEALLQG-QVLEDLEDRLHFFIEECDYLQGFQVLCDLTDGFSGLGSKVTEYLQDSYGGRGILTWGVAP--VNHPDTSS-MKDLYHMMNCALGTLQMANHSSLFCPLTLRGGLCRRPPP-PTAFPLLNCDPLLWYHSSSVLALALDALTVSYRMRHCSATMWQLSDALTTSGRKVVSAYGSVPFPMMLGGCLPDALDAFSNAVPWRSLSACPEISDRRFCFSQSVTLKGVDEQSLVS-RLLPGMEAPSPLHYERSGEDVLSAYVRSHYPSSPLAVQLVSSGSKVTPPFP-QIFSPSLSAQGFLQSHSTPASPSCPPVSCLPVLTSLQSSPAVGLQLSELQRACASLDLRRVAPSFLTHGPEHAEISEYLEQLRNLAHCYR--------------QSHSRSSSEEDDDD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O01939-1", "uniprot_id": "MST_DROME", "id": "O01939-1", "name": "Protein misato", "aln": "---------------MDYTREILTFQFGTYANYVGTHFWNQQEANFRYGDESEQVAEEQLPNNDILYREG-RNDLNRTTYTPRLLSVDLSGTLGHLPVTGELYGNFVQRDEELLPLSTGEELEQVRKRAEESGVCSPEQLEVQEQSKASISEYQRDLLKNAVVPEKN----------------YQLAATANSWVDFLYARYHPRTLNVLPGLIRDPTAQALGTYSAGTEMWQEVSFNEEFCDRIRLYVEECDGLQGFHVLFDIDDGFGGLAGKCLEHLNDEYSRASFALPLHYPRITSYPQADTRLSHSIRVVNNVLGYHQLSEQALMFTPLSTLETIWRNNNLKSRSLPGLQWETDNLYQTSALLAAFFDTATLSYRLRQTPESLLRFCECVTPAGRKMTAAGLALPFGLREGQDLIEFLDQSGDHALLTQLTPGCEPGTSY--VVQSVTARGIPAERLKRPRELAGDQLRMAAYSCDSISHMLQLYYQCTYHGSVTNAAATPLPLKTQLPFPYEMFAAGISRDGYRLPEG-AERETGSRVDSAPMLAAVQNSTKLGEHLDNVHAQSHRVQLAKLQ-AYSNSGLERDEYDTALDQLLEFRDLYA----------------DSQYL-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03652-1", "uniprot_id": "DML1_YEAST", "id": "Q03652-1", "name": "Protein DML1", "aln": "------------------MHEVVTISVSQRANHLTTQFFNIQEGYLQLSKEQQVNDS------KIFLNSVVDKVSKTISYAPRALLWDARTGNGSLGTYQYSESQ-DYHFGNEDKFKEQTVIKTHPRIPKSEYQSSLDAGAPLPCLNRENTMYWSDYSKLIYGPSSFN---------------------------ILRNWYHDTENPNQPDFQNLGE-RKFDRYSIGYDEFTENYLQEFFDGNLHRELEKCDTLQGFNLVSDMESGWGGFSSALLVELRNELPKKAVFSWGHNE---DDP------------FTDDFPMKRLSKKWLPIISNKLRSTINMMQES-DLYFPLYAAPGLTNWETAGKSCRIFDSINAT--ISQSNLEQRKTMDYLTTAITLGYSSRNMVTG-MVIGD------TDYSFCSRVLPFKNSHKPNSTH-IFSKSFIDRGNQTHKHHS--------------EPDSRSKMIEMYTHRYFP-----SDTIPTEFSNDREFVLELESSEKNRDIFKHWN-------------EFVVRYFKNDSDREELKNELSDYASAYESGWYE----DEDSGDDDM-------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. .. : . : . *:. . * . . . .:. . :* * . : :. * * : ..:: :*:** ****::: *: .*:.*... *.:. .. .. : ::: . . . : :* :. :. . :*: . . : : : :: . :: :. : * . :. . . :*. :* : ..:: * . : .: : . :. . . . : : . : ", "identical_positions": 23, "similar_positions": 105, "identity": "3.63%" }, { "cls_id": "homologset.agr.SGD:S000004825", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADS9-1", "uniprot_id": "D4ADS9_RAT", "id": "D4ADS9-1", "name": "Protein EFR3 homolog A", "aln": "-------------------------MPTRVCCCCSALRPRYKRLVDNIFPE--DPKDGLVKADMEKLTFYAVSAPEKLDRIGAYLAERLSRDVVRHRSGYVLIAMEALDQLLMACHSQS-IKPFVESFLHMVAKLLESGEPK----LQVLGTNSFVKFANIEEDTPS---------YHRRYDFFVSRFSAMCHSCHSDPEIRTEIRIAGIRGIQGVVRKTVNDELRATIWEPQHMDKIVPSLLFNMQ---KIEEVDSRLGPPSSPSAADKE--ENPAVLAESCFRELLGRATFGNMNNAVRPVFAHLDHHKLWDPNEFAVHCFKIIMYSIQAQYSHHVIQEILGHLDARKKDSPRVRAGIIQVLLEAVAIAAKGSIGPTVLEVFNTLLK-HLRLSVELEASDSQKGSVGSVSL--SSKDNDEKIVQNAVIQTIGFFGSNLPDYQRSEIMMFIMGKVPVFGTSTHTLDISQLGDLGTRRIQIMLLRSLLMVTSGYKAKTIVTALPGSFLDPLLSPSLMEDYELRQLVLEVMHNLMDRHDNRAKLRGIRIIPDVADLKIKREKICRQDTSFMKKNGQQLYRHIYLGCKEEDNVQKNYELLYTSLALITIELANEEVVIDLIRLAIALQDSAIINEDNLPMFHRCGIMALVAAYLNFVSQMIAVPAFCQHVSKVIETRTMEAPYFLPEHIFRDKCMLPKSLEKHDKNLYFLTNKIAESLGGSGYSVERLS--VPYVPQVTDE------------DRLSRRKSIVDTVSIQVDILSNSV-PSDDVVSNTEEITFEALKKAI-DTNGMEEQE-KEKRRLVIEKFQKAPFEEIAAQCESKANLLHDRLAQILELTIRPPPSPSGTLTVTSGHAQYQSVPVYEMKFPDLCVY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG67-1", "uniprot_id": "EFR3A_MOUSE", "id": "Q8BG67-1", "name": "Protein EFR3 homolog A", "aln": "-------------------------MPTRVCCCCSALRPRYKRLVDNIFPE--DPKDGLVKADMEKLTFYAVSAPEKLDRIGAYLAERLSRDVVRHRSGYVLIAMEALDQLLMACHSQS-IKPFVESFLHMVAKLLESGEPK----LQVLGTNSFVKFANIEEDTPS---------YHRRYDFFVSRFSAMCHSCHSDPEIRTEIRIAGIRGIQGVVRKTVNDELRATIWEPQHMDKIVPSLLFNMQ---KIEEVDSRLGPPSSPSAADKE--ENPAVLAESCFRELLGRATFGNMNNAVRPVFAHLDHHKLWDPNEFAVHCFKIIMYSIQAQYSHHVIQEILGHLDARRKDSPRVRAGIIQVLLEAVAIAAKGSIGPTVLEVFNTLLK-HLRLSVELEANDSQKGSVGSVTV--SSKDNDEKIVQNAVIQTIGFFGSNLPDYQRSEIMMFIMGKVPVFGTSTHTLDISQLGDLGTRRIQIMLLRSLLMVTSGYKAKTIVTALPGSFLDPLLSPSLMEDYELRQLVLEVMHNLMDRHDNRAKLRGIRIIPDVADLKIKREKICRQDTSFMKKNGQQLYRHIYLGCKEEDNVQKNYELLYTSLALITIELANEEVVIDLIRLAIALQDSAIINEDNLSMFHRCGIMALVAAYLNFVSQMIAVPAFCQHVSKVIETRTMEAPYFLPEHIFRDKCMLPKSLEKHDKNLYFLTNKIAESLGGSGYSVERLT--VPYVPQVTDE------------DRLSRRKSIVDTVSIQVDILSNSV-PSDDVVSNTEEITFEALKKAI-DTNGMEEQE-KEKRRLVIEKFQKAPFEEIAAQCESKANLLHDRLAQILELTIRPPPSPSGTLTVTSGHTQYQSVPVYEMKFPDLCVY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14156-1", "uniprot_id": "EFR3A_HUMAN", "id": "Q14156-1", "name": "Protein EFR3 homolog A", "aln": "-------------------------MPTRVCCCCSALRPRYKRLVDNIFPE--DPKDGLVKTDMEKLTFYAVSAPEKLDRIGSYLAERLSRDVVRHRSGYVLIAMEALDQLLMACHSQS-IKPFVESFLHMVAKLLESGEPK----LQVLGTNSFVKFANIEEDTPS---------YHRRYDFFVSRFSAMCHSCHSDPEIRTEIRIAGIRGIQGVVRKTVNDELRATIWEPQHMDKIVPSLLFNMQ---KIEEVDSRIGPPSSPSATDKE--ENPAVLAENCFRELLGRATFGNMNNAVRPVFAHLDHHKLWDPNEFAVHCFKIIMYSIQAQYSHHVIQEILGHLDARKKDAPRVRAGIIQVLLEAVAIAAKGSIGPTVLEVFNTLLK-HLRLSVEFEANDLQGGSVGSVNLNTSSKDNDEKIVQNAIIQTIGFFGSNLPDYQRSEIMMFIMGKVPVFGTSTHTLDISQLGDLGTRRIQIMLLRSLLMVTSGYKAKTIVTALPGSFLDPLLSPSLMEDYELRQLVLEVMHNLMDRHDNRAKLRGIRIIPDVADLKIKREKICRQDTSFMKKNGQQLYRHIYLGCKEEDNVQKNYELLYTSLALITIELANEEVVIDLIRLAIALQDSAIINEDNLPMFHRCGIMALVAAYLNFVSQMIAVPAFCQHVSKVIEIRTMEAPYFLPEHIFRDKCMLPKSLEKHEKDLYFLTNKIAESLGGSGYSVERLS--VPYVPQVTDE------------DRLSRRKSIVDTVSIQVDILSNNV-PSDDVVSNTEEITFEALKKAI-DTSGMEEQE-KEKRRLVIEKFQKAPFEEIAAQCESKANLLHDRLAQILELTIRPPPSPSGTLTITSGHAQYQSVPVYEMKFPDLCVY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZQ18-1", "uniprot_id": "EFR3B_MOUSE", "id": "Q6ZQ18-1", "name": "Protein EFR3 homolog B", "aln": "--------------------------MYGVCGCCGALRPRYKRLVDNIFPE--DPEDGLVKTNMEKLTFYALSAPEKLDRIGAYLSERLIRDVGRHRYGYVCIAMEALDQLLMACHCQS-INLFVESFLKMVAKLLESEKPN----LQILGTNSFVKFANIEEDTPS---------YHRSYDFFVSRFSEMCHSSHDDLEIKTKIRMSGIKGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQ---HVEEAESRS--PSPLQAPEKEK-ENPAELAERCLRELLGRAAFGNIKNAIKPVLIHLDNHSLWEPKVFATRCFKIIMYSIQPQHSHLVIQQLLSHLDANSRSAATVRAGIVEVLSEAAIIAATGSVGPTVLEMFNTLLR-QLRLSIDYALTGSYDGAVSLGSK--IIKEHEECMFQEAVIKTIGSFASTLPTYQRSEVILFIMSKVPLP-SVHHPVETGRTGENRNRLTQIMLLKSLLQVSTGFQCNNMMSALPSNFLDRLLSTALMEDAEIRLFVLEILISFIDRHGNRHKFSTISTLGDISVLKLKVDKCSRQDTVFMKKHSQQLYRHIYLSCKEETNIQKHYEALYGLLALISIELANEEVVVDLIRLVLAVQDVAQVNEENLPTYNRCALYALGAAYLNLISQLTTVPAFCQHIHEVIETRKKEAPYMLPEDVFVEKPRLSQNLDGVVIEFLFRQSKISEVLGGSGYNSDRLC--LPYIPQLTDE------------DRLSKRKSIGETISLQVEVESRNS-PEKEERVPAEEITYETLKKAIVDSVAVEEQE-RERQRQVVEKFQKAPFEEIAAHCGARASLLQSKLNQIFEITIRPPPSPSGTISAAYGQPQNHSIPVYEMKFPDLCVY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IGJ0-2", "uniprot_id": "EFR3_DROME", "id": "Q8IGJ0-2", "name": "Protein EFR3 homolog cmp44E", "aln": "MALIRCCFEPPELPEFFDSFVQKCTDPSCCCGCCSALRPRYKRLVDNIFPV--NPEDGLVKSNMEKLTFYSLSSPDKLDRIGEYLYQKATKDINRKRYKLAEIAMEAMDLLLQACHAQTTLNLFVESFLRMVQKLLEDSNPN----LKIMATNSFVKFANINEDTPS---------YHRRYDFFISKFSSMCHS--DAASMRDSLRLAGIKGLQGVIRKTVSDDLVENIWEAEHMEKIVPSLLFNMQFCVNVMFVKKNLLASGDLTPVEDATNVTPPALAEEVLRELVGRASFGHIRSVLKPLLTHLDRHELWVPNTFAIHTFRIVMISIQPQYSYTVVETLMQHLDNNFKSSPKTRTSLAVVLSKIIAIAAGESVGPSALDIINNLLT-HLRTSVSTTSEITP----------------EESQYQEALINALGEFANHHPDYQKIEIMLFIMNTVPDLSKKSK----------GDQMLQNILLKSLLKVGTQYSTVSFEKAFPASFLQPLLKMARAPHNPTRMVVMQILQALLDRHQNEQVLSSVSVKP---YPALSQEPPSRSDIIFTHKYGANIMQALIDSMALSDRVDA-LTSSFNTAALLIVEMSCNETVQEFLLFILGIQQVACT-VDTLGNVHKCSLHAISIGLLVLISRVSGINNLLEYAQKIVDARREEASHFLPP-LLEPKKLAGKTFNLQLPHLAIDKLALGECLQNAGMDAQRLNTGAPYSLNQTDHPGHRHSWVESVSNQLTQRNSSADLTVYNGDVDSVSSSPGVCKKLLAPEFNFDAMKRALAEPTEAAKREQRERQMQIVRTFREGEFDDLMRRTEPKHDLIQNRLNELFN-SLAVERQITQSDTKSSQLQASNEKPIYETNFPELFYY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03653-1", "uniprot_id": "EFR3_YEAST", "id": "Q03653-1", "name": "Protein EFR3", "aln": "----------------------------MQLSMRMMFTPKHQKLVNQCYPTGRTTDKKPKSSETSYLLYYVNSRRSKLEKVSTYLIKRSTSDLNHRRIGNIAVTLDLMNKIVLHCKENL--NVFVKDFLYIMNKVLSNNNFNNDVSVVELIELAFSSICQNLDDVLCNGDMEFVQLYQNFVDLFFKIVTERIHNDDMLLKCCIDISNTNSVSSNPQLNHFVSKSVAYTISKFQERNPKFKTLSLEAA---LESNLGKRLSRTQTRTIGLDKAAEDNHDLSVKALQSYFNTTETDKLNLSIRTLLRCLQSTPNKE-------LLEFVCNGIPVQLRYIVILLLVRQLSDKDKN---VNPIVSLKLMSSLLVSDVSIVGLSVLDIMRKLLNFQLKNATNKEVVAQSCITMTDLNHKTYYAEQTSDMLYELLLKLKSDTVKDVEKNAVVEDIDFLVEHITQP---------------SISLELFIDLAHYMKNHIICLFNIVETEVPSSILFSKLYS-LLRELDSHGVQKEMMEEIFDKYGKMALLS---------GLNYFLENVSEPEYTYYSYHLQAANFLKLNDYKSQTEYKMQTRTLFTKEDLLSYYSDTGSNKYSKKGAQILLSRDNQISTSDL--LSDSQVRTTPLEYKNVPNAIFSNGKAVYDNNDFAAKQNK------------FDNSIDDNIEEANDTVISDANAKGSIYRFVAEDARSWKTMRATAPKVSDL------------KKTMNEKNIPNNMKRDGSFRGSQS---VKSRVTNITFLLNELKTFSDDANKIKDPD--EENIVGLDKIDVARSNSLRLAPISSLSDRSS-IGNRKSFLQKTATGENQNDDFKDANEDLHSLSSRGKIFSST---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *::::**:: :* ... .:: . * :* * .**:::. ** :: *: ::* :::: :: :: *: : : **:.** :: *:*.. : : : : :* .:.: :*. . *:. *:*.. .: *. . .: :. . : :.: *...: .* . :. : . :* :: .. . . *: ::. .. : .::. ::.:: *: :.:: .* * : *: :: :*. . :. ... : * . :: :* :.*:::..** :*: : . . : ::: . . * : *:: :. : * : . . .*..:* * . : . ::: ::*:: : : : .. : : . . . . : *: . . : :. . * . : : . . : .. : . ..:: . .. . . . : :* .: ..:. : : .. . . : : :* :. . : *.. : .: . :.: . . . : : . . . :. . *.. ", "identical_positions": 54, "similar_positions": 253, "identity": "6.1%" }, { "cls_id": "homologset.agr.SGD:S000004826", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08837-1", "uniprot_id": "CDC5L_RAT", "id": "O08837-1", "name": "Cell division cycle 5-like protein", "aln": "MP--RIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKKKRG---VDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAS-QDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNG----AEGLTPRSGTTPKPVTNATPGR----TP--LRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGLLGLPAPKNDFEIVLPENAEKELEEREMDDTYIEDAADVDARKQAIRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPLNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNNSEHITYLEHSPYEKFSKEDLKKAQDVLVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLLKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQQRYADLLMEKETLQAKF-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6A068-1", "uniprot_id": "CDC5L_MOUSE", "id": "Q6A068-1", "name": "Cell division cycle 5-like protein", "aln": "MP--RIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKKKRG---VDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAS-QDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNG----AEGLTPRSGTTPKPVTNATPGR----TP--LRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGLLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPLNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNNSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQQRYADLLMEKETLQAKF-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99459-1", "uniprot_id": "CDC5L_HUMAN", "id": "Q99459-1", "name": "Cell division cycle 5-like protein", "aln": "MP--RIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKAAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRG---VDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEIARQTAEESGITNSASSTLLSEYNVTNNSVALRTPRTPAS-QDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNG----AEGLTPRSGTTPKPVINSTPGR----TP--LRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGLLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPLNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKTVGFGTNNSEHITYLEHNPYEKFSKEELKKAQDVLVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPGQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQHRYADLLLEKETLKSKF-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1W2P855-1", "uniprot_id": "A0A1W2P855_MOUSE", "id": "A0A1W2P855-1", "name": "Cell division cycle 5-like protein", "aln": "MP--RIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRG---VDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAP-QDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNG----AEGLTPRSGTTPKPVTNATPGR----TP--LRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1W2P7H4-1", "uniprot_id": "A0A1W2P7H4_MOUSE", "id": "A0A1W2P7H4-1", "name": "Cell division cycle 5-like protein", "aln": "MP--RIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRG---VDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAP-QDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNG----AEGLTPRSGTTPKPVTNATPGR----TP--LRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1W2P7Z8-1", "uniprot_id": "A0A1W2P7Z8_MOUSE", "id": "A0A1W2P7Z8-1", "name": "Cell division cycle 5-like protein", "aln": "MP--RIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRG---VDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAP-QDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNG----AEGLTPRSGTTPKPVTNATPGR----TP--LRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1W2P6Q8-1", "uniprot_id": "A0A1W2P6Q8_MOUSE", "id": "A0A1W2P6Q8-1", "name": "Cell division cycle 5-like protein", "aln": "MP--RIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRG---VDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAP-QDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNG----AEGLTPRSGTTPKPVTNATPGR----TP--LRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1W2P7S8-1", "uniprot_id": "A0A1W2P7S8_MOUSE", "id": "A0A1W2P7S8-1", "name": "Cell division cycle 5-like protein", "aln": "MP--RIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRG---VDYNAEIPFEKKPALGFYDTSEENYQALDADFRKMRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAP-QDRILQEAQNLMALTNVDTPLIGGLNTPLHESDFSGVTPQQQVVQTPNTVLSTPLRTPSNG----AEGLTPRSGTTPKPVTNATPGR----TP--LRDKLHINPEDGMADHSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQATRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPFDVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNDSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSCYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLEEDVQRQQEREKELQQRYADLLMEKETLQAKF-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9W0R0-1", "uniprot_id": "Q9W0R0_DROME", "id": "Q9W0R0-1", "name": "", "aln": "MP--RIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEDEKLLHLAKLMPTQWRTIAPIIGRTAAQCLERYEYLLDQAQRKEDGEDTMDDPRKLKPGEIDPNPETKPARPDPKDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLATLQKRRELRAAGIGSGN-RKRIKG---IDYNAEIPFEKRPAHGFYDTSEEHLQKNEPDFNKMRQQDLDGELRSEKEERERKRDKQKLKQRKENEVPTAMLQN---MEPERKRSKLVLPTPQISDMELQQVVKLGRASEMAKEIAGESGIET--TDALLADYSIT--PQVAATPRTPAPYTDRIMQEAQNMMALTHTETPLKGGLNTPLHESDFSGVLPKAASIATPNTVIATPFRTQREGGAATPGGFQTPSSGALVPVKGAGGATGVVNTPAYVRDKLSINPEESMGVTETPAHYKNYQKQLKSTLRDGLSTLPAPRNDYEIVVPEQEESERIET-NSEPAVEDQADVDARLLAEQEARRKRELEKRSQVIQRSLPRPTEVNTKILRPQSEKQNLTEQQQAEELIKHEMITMQLYDSVKDPVP--GQSQHKLEQLQS-------YFKANPYEDISQQELAKAKQMLTEEMEVVKERMAHGELPLDVYAQVWQECLGQVLYLPSQHRYTRANLASKKDRLESAEKRLETNRRHMAKEAKRCGKIEKKLKILTGGYQARAQVLIKQLQDTYGQIEQNSVSLSTFRFLGEQEAIAVPRRLESLQEDVRRQMDREKELQQKYASLVEERDSLYSQIEHITGVRPTAQQLLPDQEA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03654-1", "uniprot_id": "CEF1_YEAST", "id": "Q03654-1", "name": "Pre-mRNA-splicing factor CEF1", "aln": "MPPVPIYVKGGVWTNVEDQILKAAVQKYGTHQWSKVASLLQKKTARQSELRWNEYLNPKLNFTEFSKEEDAQLLDLARELPNQWRTIADMMARPAQVCVERYNRLLESED--SGGAALSTGVTDLKAGDINPNAETQMARPDNGDLEDEEKEMLAEARARLLNTQGKKATRKIRERMLEESKRIAELQKRRELKQAGINVAIKKPKKKYGTDIDYNEDIVYEQAPMPGIYDTSTEDRQ-IKKKFEQFERKVNRKGLDGNKDKPSKKNKDKKRKHDENEHVEKAALGESTTLTDEYKKPKLILSAPGTKQGKVTYKKKLESKRQKLIEAQATG--------------------------------------------------------------------------TVLTPKELLPHDSGQEDNE-------------------------------------------------RSNIKSGKQLKSRIRKFLVQMFASLPSPKNDFEIVLSEDEKEE------------DAEIAEYEKEFENERAMNEEDNFIEPPSQNDAPRVSLVAVPLAYSTLPIPEFKNNPQS--------------------------------------------AIDNKYNLLVANAINKEPHMVPEDTVDFLKEVES------------------------RMQHITQGRTSMKIQFKTAMPPTEVLLESIQSKVESIEQLQRKLQHVQP--------LEQQNNEMCSTLCHHSLPALIEGQRKYYADYYAYR------QEIRSLEGRRKRLQAMLNSSSSI---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * :***** *.**:*****: ** .:***::****::*:*:*.: ** *:*:*.:: **:*:**: :**.**: :*.****** ::.*.* *:*:*: **: .. . .**.*:*:**.**: **** *::::* ***:****** *******.** **: ***::*:* *******: *** : : : :*** :* :*: * *:**** *. * . .*.::.:: * .:*: .:* ..:: *: ::..: .* * *:.**:*.:* .: :: *: : : . : **: ::. : . *: : . :. * : **:*:**:***:.*: :.* * .: . .: .* : *.. ** : * : . :.: :: . *: : : : * : :: . : : : : . :* * :::: * : .:.: ::::*:: : * :* :: . : : : * :::: *.*.** . ", "identical_positions": 164, "similar_positions": 184, "identity": "19.59%" }, { "cls_id": "homologset.agr.SGD:S000004827", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UBS4-1", "uniprot_id": "DJB11_HUMAN", "id": "Q9UBS4-1", "name": "DnaJ homolog subfamily B member 11", "aln": "MAPQNLSTFCLLLLYLIGAVIAGRDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPDDPQAQEKFQDLGAAYEVLSDSEKRKQYDTYGEEGLKDGH----QSSHG-DIFSHFFGDFGFMFGG-----TPRQQDRNIPRGSDIIVDLEVTLEEVYAGNFVEVVRNK-----------PVARQAPGKRKCNCR-------------QEMRTTQLGPGRFQMTQEVVCDECPNVKLVNEERTLEVEIEPGVRDGMEYPFIGEGEPHVDGEPGDLRFRIKVVKHP--IFERRGDDLYTNVTISLVESLVG-FEMDITHLDG-HKVHISR--DKITRPGAKLWKKGEGLPNFDNNNIKGSLIITFDVDFPKEQLTEEAREGIKQLLKQGSVQKVYNGLQGY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPQ2-1", "uniprot_id": "DJSHV_DROME", "id": "Q9VPQ2-1", "name": "DnaJ homolog shv", "aln": "MQLIKCLVIIQLSLLLVEESFAGRDFYKILNVKKNANTNEVKKAYRRLAKELHPDKNKDDPDASTKFQDLGAAYEVLSNPDKRKTYDRCGEECLKKEG----MMDHGGDPFSSFFGDFGFHFGG-----DGQQQD--APRGADIVMDLYVSLEELYSGNFVEIVRNK-----------PVTKPASGTRKCNCR-------------QEMVTRNLGPGRFQMIQQTVCDECPNVKLVNEERTLEIEVEQGMVDGQETRFVAEGEPHIDGEPGDLIVRVQQMPHP--RFLRKNDDLYTNVTISLQDALVG-FSMEIKHLDG-HLVPVTR--EKVTWPGARIRKKGEGMPNFENNNLTGNLYITFDVEFPKKDLTEEDKEALKKILDQSSINRIYNGL---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25303-1", "uniprot_id": "SCJ1_YEAST", "id": "P25303-1", "name": "DnaJ-related protein SCJ1", "aln": "-MIPKLYIHLILSLLLLPLILA-QDYYAILEIDKDATEKEIKSAYRQLSKKYHPDKNAGSEEAHQKFIEVGEAYDVLSDPEKKKIYDQFGADAVKNGGGGGGPGGPGAGGFHDPFDIFERMFQGGHGGPGGGFGQRQRQRGPMIKVQEKLSLKQFYSGSSIEFTLNLNDECDACHGSGSADGKLAQCPDCQGRGVIIQVLRMGIMTQQIQQMCGRCGGTGQIIKNECKTCHGKKVTKKNKFFHVDVPPGAPRNYMDTRVGEAEKGPDFDAGDLVIEFKEKDTENMGYRRRGDNLYRTEVLSAAEALYGGWQRTIEFLDENKPVKLSRPAHVVVSNGEVEVVKGFGMP--KGSKGYGDLYIDYVVVMPKT--FKSGQNMLKDEL---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * *: :* :*:* ** : :.*. :::*.***:*: : ***:* .. :* ** ::* **:***:.:*:* ** * : :*. . * . * *. * * * : **. * :: ::*::.*:*. :*.. * .. . .*: * *:: * : *. * . *:.:::: :.::: * . :.*.* * :.*** ...: : *:.*:** . .:* ::* * :. * .** : * ::* . :. * ** *:* ...: *.* * : * :** :. :: :*. * ", "identical_positions": 86, "similar_positions": 110, "identity": "21.61%" }, { "cls_id": "homologset.agr.SGD:S000004829", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0G2-1", "uniprot_id": "SRPK3_MOUSE", "id": "Q9Z0G2-1", "name": "SRSF protein kinase 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------MSANAGGSG-SVDCGG----------------------------------------------------SSSSSQTS-----------------------------------------------------CGPESSGSELTPATPAPRLLQG-------------------------------LLGSDDEEQEDPKDYCKGGYYPVKIGDLFN-GRYHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETAVDEIKLLKCVRDSDPSDPK---RETIVQLIDDFRISGVNGVH--VCMVLEVLGHQLLKWIIKSNYQGLPVPCVKSIVRQVLHGLDYLHTKCKIIHTDIKPENILLCVG--DAYIRRLAAEATEWQQSGAQPPSRSTVSTAPQEVL----IGKLSKNKRKKMRRKRKQQKRLLEERLRDLQRLEA------------------------------------------------------------------------------------------------------------------------------------MEAAVQAEDSS------------------------SRLERG-------SGSTSSSGCHPEGTRAGPSPASSSPVP-GGERSLSPSS--------------------------------------QTSGFSGSLFSTASCSILSGSSN-------------------------------QRETGGLLSPSTPFGASNLLVNPLEPQNADKIK-----------IKIADLGNACWVHKHFTEDIQTRQYRAVEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGE-DYSRDEDHIAHIVELLGDIPPAFALSGRYSREFFNRRGELRHIPNLKHWGLYEVLMEKYEWPLEQATQFSAFLLPMMEYIPEKRASAADCLQHPWLNP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2KAH6-1", "uniprot_id": "A0A0G2KAH6_RAT", "id": "A0A0G2KAH6-1", "name": "SRSF protein kinase 3", "aln": "------------------------------------------------------------------------------------------------------------------------MHWPRLGPTGTVVQCTRALGCDT-----------RMSASAGGSG-GMDCGG----------------------------------------------------SSSSSQTS-----------------------------------------------------CGPESSSSELAPATPAPRLLQG-------------------------------LLGSDDEEQEDPKDYCKGGYYPVKIGDLFN-GRYHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETAVDEIKLLKCVRDSDPSDPK---RETIVQLIDDFRISGVNGVRPDVCMVLEVLGHQLLKWIIKSNYQGLPVPCVKSIVRQVLHGLDYLHTKCKIIHTDIKPENILLCVG--DAYIRRLAAEATEWQQSGAQPPSRSTVSTAPQEVL----TGKLSKNKRKKMRRKRKQQKRLLEERLRDLQRLEA------------------------------------------------------------------------------------------------------------------------------------MEAAVQTEDSS------------------------SRLEQG-------SGSTSSSGCHPEGTRAGPSPASSSPVPTGGERSLSPSS--------------------------------------QTSGFSGSLFSTASCSVLSGSSN-------------------------------QRETGGLLSPSTPFGASNLLVNPLEPQNADKIK-----------IKIADLGNACWVHKHFTEDIQTRQYRAVEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGE-DYSRDEDHIAHIVELLGDIPPAFALSGRYSREFFNRRGELRHIHNLKHWGLYEVLMEKYEWPLEQATQFSAFLLPMMEYIPEKRASAADCLQHPWLNP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UPE1-1", "uniprot_id": "SRPK3_HUMAN", "id": "Q9UPE1-1", "name": "SRSF protein kinase 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------MSASTGGGGDSGGSGG----------------------------------------------------SSSSSQAS-----------------------------------------------------CGPESSGSELALATPVPQMLQG-------------------------------LLGSDDEEQEDPKDYCKGGYHPVKIGDVFN-GRYHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETAVDEIKLLKCVRDSDPSDPK---RETIVQLIDDFRISGVNGVH--VCMVLEVLGHQLLKWIIKSNYQGLPVPCVKSIVRQVLHGLDYLHTKCKIIHTDIKPENILLCVG--DAYIRRLAAEATEWQQAGAPPPSRSIVSTAPQEVLQ---TGKLSKNKRKKMRRKRKQQKRLLEERLRDLQRLEA------------------------------------------------------------------------------------------------------------------------------------MEAATQAEDSG------------------------LRLDGG-------SGSTSSSGCHPGGARAGPSPASSSPAP-GGGRSLSAGS--------------------------------------QTSGFSGSLFSPASCSILSGSSN-------------------------------QRETGGLLSPSTPFGASNLLVNPLEPQNADKIK-----------IKIADLGNACWVHKHFTEDIQTRQYRAVEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGE-DYSRDEDHIAHIVELLGDIPPAFALSGRYSREFFNRRGELRHIHNLKHWGLYEVLMEKYEWPLEQATQFSAFLLPMMEYIPEKRASAADCLQHPWLNP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TFD0-1", "uniprot_id": "A0A8N7TFD0_DANRE", "id": "A0A8N7TFD0-1", "name": "non-specific serine/threonine protein kinase", "aln": "----------------------------------------------------------------------------------------------------------------MSSCSRSHFNRTSCCQYSAEPQCACSEPTEANVREVTAVPMISMNVSSSDNNLPQNSHGKKQKKKNKKHRKAAVAAAVEISS--------LELGPQIPSSDELCHILTIHRSATPPESSPTPPLNLSQSPPDLQPPAP------------------IPHSIPITVVPSPVVVSSPETPSTPIAPSLGLPSILSSTPPTPQAPSNQPTPPQALSPPPPDFSPPPAELLGSDDEEQENPSDYCKGGYYPVKIGDLFN-GRYHVVRKLGWGHFSTVWLCWDLQRKRFVALKVVKSAQHYTETALDEIKLLKCVRDSDPTDSK---RERLVQLIDDFKISGVNGVH--VCMVLEVLGHQLLKWIIKSNYMGLPLICVKSILRQVLEGLDYLHTKCKIIHTDIKPENILLEVN--EVYVRRLAAEATIWQKAGAPPPSGSSVSTAPREKQ----MGKMSKNKKKKLKRKAKRQQQLLDERLIDLQRMEE------------------------------------------------------------------------------------------------------------------------------------LDGVLPSDASGNTRAL-------------------WRLSEDEEDNVKHAQTNGNGALNKQSPESGSSWLEESCNGYGPLRFSSPGS--------------------------------------GLSGLSGSILSATSESALSTLSG-------------------------------YSTERSLLSPNS-YSAADFLVNPLESQNADKIS-----------IKIADLGNACWVHKHFTEDIQTRQYRALEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGE-DYTRDEDHIAHIIELLGAIPPHFALSGRYSREYFNRRGELRHIANLKPWGLFEVLLEKYEWPLDQAAQFSDFLLTMLEFIPEKRATAAQCLQHPWINS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6YZP6-1", "uniprot_id": "A0A8M6YZP6_DANRE", "id": "A0A8M6YZP6-1", "name": "non-specific serine/threonine protein kinase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MERKVLALQARKKR-------------------------------------------------AKAK--KSTKK-----------------------------------------------------PAHPPRGASQQQPPPTETQIQEPDEE-------------------------ILGSDDEEQEDPNDYCKGGYHHVKIGDLLN-SKYHVIRKLGWGHFSTVWLAWDIQGKRFVAMKVVKSAEHYTETALDEIKLLRSVRNTDPDDPN---REMVVQLLDDFKISGVNGTH--VCMVFEVLGHHLLKWIIKSNYQGLPLPCVKSIIRQVLQGLDYLHTKCQIIHTDIKPENILMSVE--ELYVRRLAAEATEWQKAGAPPPSGSAVSTAPAPKQ----APKMSKNKKKKLKKKQKRQAELLEKCIMDLEEMEI--GPEGR------------EEE-EDDPESPKS-----PSCAPLR----------------------------------------------------------------------------------------QASLQEIATEDIIMDTRERLTSDASVELNCNGCLHSSKTQPEEDEQGDLQYGQLLQEDHHNANAGPEDTAQSMYEY--CNGAESPE-----------------------LDQACYSNG------TSGQEQ-----LEDGELATEEQH-----------------------QQKTRTRAREQNKDKIKD-DKLSAGSLLVNPLDPLNADKIK-----------VKIADLGNACWVHKHFTEDIQTRQYRSLEVLLGSGYNTPADIWSTACMAFELATGDYLFEPHSGE-DYSRDEDHLALIIELLGHIPRHYALSGKFSQEYFCRKGDLKHITKLKPWGLLDVLMDKYEWPQEEAQTFSDFLLPMLELLPEKRATASDCLRHPWLAL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7UYM5-1", "uniprot_id": "A0A8N7UYM5_DANRE", "id": "A0A8N7UYM5-1", "name": "non-specific serine/threonine protein kinase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MERKVLALQARKKR-------------------------------------------------TKTK--KPGKK-----------------------------------------------------PDPHPRGAAQQP-----DALQEQDEE-------------------------ILGSDDEEQEDPNDYCKGGYHHVKIGDLFN-GRYHVIRKLGWGHFSTVWLAWDTQGKRFVAMKVVKSAEHYTETALDEIKLLKAVRNTDQNDPS---REKVVQLLDDFKISGVNGTH--VCMVFEVLGHHLLKWIIKSNYQGLPLPCVKSIIRQVLQGLDYLHTKCKIIHTDIKPENILMDVN--EAYVKRLAAEATEWQKSGAPPPSGSAVSTAPAPKQ----ATKMSKNKKKKMKKKQKRQAELLEKRILEIEGLEK--GLDGG------------EEEDEDETETPDS-----TPSVPS-----------------------------------------------------------------------------------------SHTLQDISTETTLDGTSEAWS---QVTGSVNGHIPS----PEDEQSLDVQQ-QMKDETPVNPYDSGNETSEPTNPYPACNGTEETE-----------------------PSPACLSAADGNGALISGMVESQGCRVQDGESLTAELKD-----------------PRAEMEAEPGTQAVPEEEESLKD-AKTAAGNLLVNPLEPLNAEKIQ-----------VKIADLGNACWVHKHFTDDIQTRQYRSLEVLIGTGYGTPADIWSTACMAFELATGDYLFEPHSGE-DYSRDEDHIALIIELLGKIPRKLVMNGKYSKEFFTKKGDLRHITKLKPWGLQDVLVEKYEWHREEAQNFSDFLLPMLDLIPEKRATAAECLRHSWINS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O70551-1", "uniprot_id": "SRPK1_MOUSE", "id": "O70551-1", "name": "SRSF protein kinase 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MERKVLALQARKKR-------------------------------------------------TKAKKDKAQRK-----------------------------------------------------PETQHRGSAPHS----ESDIPEQEEE-------------------------ILGSDDDEQEDPNDYCKGGYHLVKIGDLFN-GRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPN---GEMVVQLLDDFKISGVNGTH--ICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVN--EQYIRRLAAEATEWQRSGAPPPSGSAVSTAPQPKP----ADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQK------------RPNKQEESESPVDRPLTENPPNKMT----------------------------------------------------------------------------------------QEKLEESNSIGQDQTLTERGGEGGAPEINCNGVIGVVNYPENSNNETLRHKEDLHNANDCDVHTLKQEPSFLNSSNGDSSPSQDTD-----------------------SCTPTAS---ETMVCQSSAEQS--LTRQDITQLEESIR----------------------ADTPSGDEQEP--NGALDSKGKFSAGNFLINPLEPKNAEKLQ-----------VKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGE-DYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHITKLKPWGLLEVLVEKYEWPQEEAAGFTDFLLPMLELMPEKRATAAECLRHPWLNS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KLN3-1", "uniprot_id": "Q4KLN3_RAT", "id": "Q4KLN3-1", "name": "SRSF protein kinase 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MERKVLALQARKKR-------------------------------------------------TKAKKDKAQRK-----------------------------------------------------PETQHRGSAPHS----ESDIPEQEEE-------------------------ILGSDDDEQEDPNDYCKGGYHLVKIGDLFN-GRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPN---GEMVVQLLDDFKISGVNGTH--ICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVN--EQYIRRLAAEATEWQRSGAPPPSGSAVSTAPQPKP----ADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQK------------RPNKQEESESPVERPLTENPPNKMT----------------------------------------------------------------------------------------QEKLEESSSIGQDQTLTEHGGEGGAPEINCNGVIGIVNYTANSNNETLRLKEDLHNANDCDGRTLKQEPSFLSSPNGDSSPSPETD-----------------------SCTPSGSEVPETMACQASVERSLTLTQQDITHLQERIR----------------------AHTPSGDEQEREHNGALDSKGKFSAGNFLINPLEPKNAEKLK-----------VKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGE-DYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHITKLKPWGLLEVLVEKYEWPQEEAAGFTDFLLPMLELMPEKRATAAECLRHPWLNS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96SB4-2", "uniprot_id": "SRPK1_HUMAN", "id": "Q96SB4-2", "name": "SRSF protein kinase 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MERKVLALQARKKR-------------------------------------------------TKAKKDKAQRK-----------------------------------------------------SETQHRGSAPHS----ESDLPEQEEE-------------------------ILGSDDDEQEDPNDYCKGGYHLVKIGDLFN-GRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPN---REMVVQLLDDFKISGVNGTH--ICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVN--EQYIRRLAAEATEWQRSGAPPPSGSAVSTAPQPKP----ADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQK------------RPNKQEESESPVERPLKENPPNKMT----------------------------------------------------------------------------------------QEKLEESSTIGQDQTLMERDTEGGAAEINCNGVIEVINYTQNSNNETLRHKEDLHNANDCDVQNLNQESSFLSSQNGDSSTSQETD-----------------------SCTPITSEVSDTMVCQSSSTVGQSFSEQHISQLQESIR----------------------AEIPCEDEQEQEHNGPLDNKGKSTAGNFLVNPLEPKNAEKLK-----------VKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGE-EYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHITKLKPWGLFEVLVEKYEWSQEEAAGFTDFLLPMLELIPEKRATAAECLRHPWLNS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O54781-1", "uniprot_id": "SRPK2_MOUSE", "id": "O54781-1", "name": "SRSF protein kinase 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVNSEK--------------------------------------------------SSSSERPEPQQKAP-------------------------------------------------LVPPPPPPPPPPP--LPDPAPP-EPEEE-------------------------ILGSDDEEQEDPADYCKGGYHPVKIGDLFN-GRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPSDPN---KDMVVQLIDDFKISGMNGIH--VCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVD--DAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKP----IGKISKNKKKKLKKKQKRQAELLEKRLQEIEELEREAER-------------KILEENITSAEASGEQDGEYQPEVTLK--------AADLEDTTEEETAKDN--------------------------------------------------------------GEVEDQEEKEDAEKENAEKDEDDVEQELANLDPTWVESPKANGHIENGPFSLEQQLEDEEDDEDDCANPEEYNLDEPNAESDYTYSSS---------------YEQFNGELPNGQHKTSE-----FPTPLFSGPLEPVACGSVISEGSP--------------LTEQEESSPSH-DRSRTVSASSTGDLPKTKTRAADLLVNPLDPRNADKIR-----------VKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSGE-DYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GM61-1", "uniprot_id": "A0A8I6GM61_RAT", "id": "A0A8I6GM61-1", "name": "SRSF protein kinase 2", "aln": "---MERRAARPAGVRSGGGGWEEEGSAAGPSARELVACGGRRSKEAEAGCGRPWAREAVGARRSSRTGGSRGGRPGRGPGPGPQCSGDAEGGARRGRGRGAGPRGRVPLAPAGAAAAAQARFPPPRPASEWRLHPGAADCRVAAASAAEPPARLPRVGMSSRKVLAIQARKRRPK---------------------------------------------REKHPKKPEPQQKAP-------------------------------------------------LVPPPPPPPPPPP--LPDPVPP-EPEEE-------------------------ILGSDDEEQEDPADYCKGGYHPVKIGDLFN-GRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPSDPN---KDMVVQLIDDFKISGMNGIH--VCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVD--GAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKP----IGKISKNKKKKLKKKQKRQAELLEKRLQEIEELEREAER-------------KILEENTTSAEASSEQDGECQPEVKLK--------EAELEDTTEEETAKDN--------------------------------------------------------------GEVEDQEEKEDTEKENTEKDEDDVEQELENIDPTWMESPKANGHIENGLFLLEQQLEDEEDEEDDCANPEEYNLDEPNAESDYTYSSS---------------YEQFNGELPNGQPKSPE-----FPTPLFSGPLEPVASDSVLSEGSP--------------LTEPEESSPSR-DRSRTVSASSTGDLPKTKTRAADLLVNPLDPQNADKIR-----------VKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSGE-DYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P78362-1", "uniprot_id": "SRPK2_HUMAN", "id": "P78362-1", "name": "SRSF protein kinase 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVNSEK--------------------------------------------------SSSSERPEPQQKAP-------------------------------------------------LVPPPPPPPPPPPPPLPDPTPP-EPEEE-------------------------ILGSDDEEQEDPADYCKGGYHPVKIGDLFN-GRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPSDPN---KDMVVQLIDDFKISGMNGIH--VCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVD--DAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKP----IGKISKNKKKKLKKKQKRQAELLEKRLQEIEELEREAER-------------KIIEENITSAAPSNDQDGEYCPEVKLK--------TTGLEEAAEAETAKDN--------------------------------------------------------------GEAEDQEEKEDAEKENIEKDEDDVDQELANIDPTWIESPKTNGHIENGPFSLEQQLDDEDDDEEDCPNPEEYNLDEPNAESDYTYSSS---------------YEQFNGELPNGRHKIPESQFPEFSTSLFSGSLEPVACGSVLSEGSP--------------LTEQEESSPSH-DRSRTVSASSTGDLPKAKTRAADLLVNPLDPRNADKIR-----------VKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSGE-DYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PYJ9-1", "uniprot_id": "A0A8M9PYJ9_DANRE", "id": "A0A8M9PYJ9-1", "name": "non-specific serine/threonine protein kinase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------MSSRKVLAIQARKRRPRGKKE-----------------------------------------KTVPHRRPDTQKAPS-------------------------------------------------DPPPPPPPPPPPPPPPPEPVAPLEPEEE-------------------------ILGSDDEEQEDPADYCKGGYHPVKIGDLFN-SHYHVIRKLGWGHFSTVWLCWDIQGKRFVAMKVVKSAQHYTETALDEIKLLRCVRETDPEDPN---KDMVVQLIDDFKISGVNGIH--VCMVFEVLGHHLLKWIIKSNYQGLPLPCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVD--DAFVRRMAVEATEWQKAGAPPPSGSAVSTAPQLKQ----VGKISKNKKKKMKKKQKRQAELLERRMLEIEALEREAEKQRADGETNAEHGPTLADSEEDEEEEEDEEEEEKQRPVRLTNHTCAEPEQPEVEDSDDGEESRTHTHTPTHTPTHTATHTPTHTPTETPTQTPTHTPTHAHTPTHTPLGRTDTPQEPERSGGAEELDGSRDGRQEEEEKAEEVEKAEEVEEETAAAPSESTEEETRQCVKEDEQTKHTRDTQDEEEEEEEEDDEEDEEDEEEEEEEEEQSTAAKTNGHVCVCVQECVSPAAPTLLCPLVESEISTTDRDASDASYELFNGDTSSLSNGARHRGTTPRFPELPLDPDPTHTLQDQAQGPDRHSDRSRTVSSSSTGDNPKARIRAADLLVNPLDPRNAEALR-----------VKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSGE-DYSRDEDHIAHIIELLGCIPRHFALSGKYSREFFNRRGELRHITKLKPWSLFDVLVEKYGWAAEEAGHFTHFLLPMLEMVPEKRASASECLHHPWLSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A6M3Q7C8-1", "uniprot_id": "A0A6M3Q7C8_DROME", "id": "A0A6M3Q7C8-1", "name": "non-specific serine/threonine protein kinase", "aln": "---------------------------------------------------------------------------------------------------------MNKADVNRRVLAIQAKKKRHKNRKRGKQNGTNPQEQSNSSQNQNPKPSSNPIPEPNRSSENLQAPDNANNSHLN-----------------------------------------APSSAAFSKATATATASTSSGGSAG----------------------------------TPDQYQPPKKTQAKAKPNTQKEHQQQPPRSSSNES--------------------YESETFSDNEDQELMEDYCKGGYHPVNIGDLFH-DRYHVIRKLGWGHFSTVWLCWDLQAMGYVAIKIVKSAPHFAETARDEIKILKTVRETDPSNPR---RHKTVQMLDDFKITGVNGTH--ICMVFEVLGDNLLKLIRKSNYRGIPLANVKTITRQVLEGLDYLHTCCKIIHTDIKPENVLLCVD--EPHVRSLATEATQLYCMNSKMYP-SLVSRAPKEYREPPITGKMSKNRKKKLKKKAKKRMELFKQQRDYLEQADGQGAINPN------------EVQNGDAGISDADEYFDANSVEDN--------------------------------------------------------------------------------------VHVAAGQPSRKQREERKAPPEQSEEAQEQDPLTEGTDKAKKKKKKKNKNKSNQSKGQQPPQLENSTSSAESSSALKSQQANGSNSTTNN----------------------KSNTNSSGTLKGQSNGKKMPLRPKQEKQGSNHQLNNNNS-------------------KPNSNSDSKISSGSVENTSSATNGPHSNSTLPTPPPPPQAKHKAKKDPALDECNVHVKIADLGNACWVDRHFTEDIQTRQYRSLEVIIGAGYNTSADIWSTACMVFELATGDYLFEPHSGE-SYTRDEDHLAHIIELLGPIPREILLNGTYAAKSFTRSCELRNISGLKPWGLMDVLLEKYEWSQKDAASFASFLTPMLEFDPNKRATAAECLQHPWLRXDTMQPGCWLRATQPATADGDGGALAGTGTGKGTRARATALKGGSPAVPADGEVGRGYIESSASVATLASISSIASTSAAAMAALKARPYLVAPFVTTASAPPTPHPHASISTSTARTAPATPTRRRIAPEDDLNLVEDLDVALAQIEDTQTHTKNKSQRFFWRKALRRVFQRRKXRRRRQDLPRWHRPARRCRRRNLAERVRRICACCAYGQILLRAARVALLSCIRWRTRGNIRNNNFYFSNH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M9P5C7-1", "uniprot_id": "A0A8M9P5C7_DANRE", "id": "A0A8M9P5C7-1", "name": "non-specific serine/threonine protein kinase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSKLKSLRHYEHLEPDLA-------------------------------EEFEDPRDYCYGGYHPVQVGDIFN-KRYKVLSKLGWGYFSTVWLCVDLRSGRHVAVKVLKSGAGFTQAGQDELTLLRCASGPTARNPL---KGRIVQLLDEFKLAGVNGIH--ICLVLELLGPDLRCWQMCFGNPGLSLSCVKHVITQVLEGLEYLHSHCKIIHTDIKPENILLCFT----------------------------------------------PHPPGG--------------------------------------------------------------------------------------------------------------------------------------------------------------------DIHTYSSSAIRN--------------------------------------TVLKAPG------ESGKLG-------------------------------------------------------------------------------------------------------------------TWGNLED---------------------ITVKIADLGSSCWVYKHFCQEIQTRQYRSLEVLLGSEYGPAADIWSVACLAFELATGDSLFEPKAGP-NFSLEEDHLAHIIELLGKIPVSVAQCGKYYYEYFNRKGDLRRIAVLRPWGLYEVLVEKYHFLLREASLFSDFLLQMLNYLPERRATAAQCLKHPWLKL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9MS50-1", "uniprot_id": "SRPK7_DROME", "id": "M9MS50-1", "name": "Serine-arginine protein kinase at 79D", "aln": "MAGLIGAANGKHHHPHLISPTHTSLPAGICSSDSGISTLSAISPPLSTSTTTASGAGGGVGGSPQLRTSPALSMLGSATATASGVTASSGCGLTAGILGPAASIDLGSSPLSHRNYSNSLKGFSFRRSFDDKIINTPYLSRAPAYTHGIPYPHFHGTQPAATTPHHLHLHHHGNGTAAGSGSGVGSGPGSGSGAGGLYQQPLSLASMTAALPLAPLYGSPLSLPLTSSQSTTKLSYRDDFLQQIGYLPTTRIYSTPTSIVDEDKAQQDFLSLSLSPPLNRRRDMPALRGPFVSLSEPRGTLSTTDEIYPDSSDS-----------------------SLYVSDEEQEDASQYCRGGYHPVVIGDIFD-NRFRVVRKLGWGHFSTVWLCRDLKDEKYVALKVVKSAPHYIETAADEIRLLEAIRDADPMDVK---RERIVRLMNHFTVRGVNGMH--TCLVFEALGCSLYKLIVKNNYQGLAIAQVRNIIRQVLEGLDYLHSKCSIIHTDIKPENILLVIDNAAAMNQQIDDEINSLRVKGVDFPDSYISSIEKQTKS----RAKWPLIEPNGSTNTNTNTSNSTATNSNSSTPLAAV-----------------------------------------------------------------------------------------------------------------------------------IMSTLDKEDTTTTTSSTLNSNTTSSLASKYSSLLGDSECNGGLGGSANINNRYRTEKKITAKSSGDCDEDAESDTLGEQSTLASTM-------------------------------------DSPTDLDPEPELDSKPNTVPEPSE-----------------------------GPIPENQSQSSQNNTYTIQSLIDNSN------------------VRVKIADLGNACYDYHHFTEDIQTRQYRSIEVLLGAPYNYTADIWSTACLAFELATGDYLFDPHAGE-SYSRDEDHLAHIVELLGSIPQSVIFRGKHGLKYFTSYGSLRNITKLKPWSLMNVLVEKYDWDPVEAKKFSDFLLPMLEYNPVIRASAAECLQHPWLEQEEFV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03656-1", "uniprot_id": "SKY1_YEAST", "id": "Q03656-1", "name": "Serine/threonine-protein kinase SKY1", "aln": "-------------------------------------------------------------------------------------------------------MGSSINYPGFVTKSAHLADTSTDASISCEEATSSQEAKKNFFQRDYNMMKKAPAPTKSKLSLALQTSKSSSSANG---------------------------------------TVQEDTSSKTEDFSTKSIK------------------------------------------------KKPDSGVESHVSIQSDSGPQSDSDLDSDSS-----------------------ISSCDERNEESLKDYRPGGYHPAFKGEPYKDARYILVRKLGWGHFSTVWLAKDMVNNTHVAMKIVRGDKVYTEAAEDEIKLLQRVNDADNTKEDSMGANHILKLLDHFNHKGPNGVH--VVMVFEVLGENLLALIKKYEHRGIPLIYVKQISKQLLLGLDYMHRRCGIIHTDIKPENVLMEIGDVEGIVQMVEALDKQKREAKRLQRHVSRSSDITANDSSDEKWAECQTSMPCGSSSNSKSRSIEKDLSKRCFRRPRRHTIITGS---------------------------------------------------------------------------------------------------------------------------QPLPSPISSSNFFEMRAHFCGSSHNSFSSVSGNRNIPSSINNNSINNGIGIKNSNNSFLNSVPHSVTRMFINEDSNDNNNNDNSKNKN--------------------------------NNNNNSNNNNNEDIMNTPLHEEQLADSLS----------------------------TFDISNISQSSDTNGPYISNTMDSNSNVSTDINSPEN-------LIQIKIADLGNACWYDEHYTNSIQTREYRSPEVLLGAPWGCGADIWSTACLIFELITGDFLFEPDEGH-SYTKDDDHIAQIIELLGELPSYLLRNGKYTRTFFNSRGLLRNISKLKFWPLEDVLTEKYKFSKDEAKEISDFLSPMLQLDPRKRADAGGLVNHPWLKDTLGMEEIRVPDRELYGSGSDIPGWFEEVRDHKRH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VXN5-1", "uniprot_id": "Q9VXN5_DROME", "id": "Q9VXN5-1", "name": "non-specific serine/threonine protein kinase", "aln": "----------------------------------------------------------MFKMKRTRVIRRKAAIIRASKRAFQEKIRKQMESCGVTQMGNASTQQSNVPMDVDADMGRKMSEDGMTDTSNTVKQPSCSKDQKQLSRKQKPSPSYNHQEQIEQRAKRPKICKKRCKQKRR-----------------------------------------MPSSLSDDGIAGRKPAKIN---------------------------------------------KYSELSYGSESSMPFEMKQQSNDNQNNNDN-----------------------AEGSGFDRQESANEYVIGGYHPVAIGDVFV-NRYHVFKKLGWGHFSTVWLCYDTQMDRYCAVKVSKSAQVYKETGIDEIMLFSQMSLHDQHKYR----SHVVGFYDFFEITGPHGRH--ICLVLEVLGDNLLKVIERCFYKGMPISNIKQIAQQVLTGLKFLHEECGIIHTDLKPENVLLASN--EVSVRTEIKTAIEVYLKANEGKLSPSSKMTKTAKR------RMQAKSKKVISFFKNHRRMLRRQGIEDLLYLAERG----------------------------------------------------------------------------------------------------------------------------------LIEPITAAMAVSDNLPFIPFGFDGFMMMSDADCRTVQNSKLPEMEGMEYKCDRINLCLKSPELFLRYVLDIIKNLDEKELSTQDKR------------------------------------RRFTQASGRGQTKKNARSRLRLASN--------------------------------AAYTTGTGWRSNRKINLNDIYPIDPANNECDVR----------VKIADLGNACYFHHHFTDDIQTKEYRALEVILGAGYCETADIWSVACLLWELATGTYLFDTHSKRGKYNLDEVHIAKIVETCGRIPWYLIRKGKHSRNFINSAGKLCNIETLKPLKLANILIRWYGWRTRQSTEFVNFLMPMLQTNPLSRISASKALESHYLCNIALPGIDIDSYYYYSVREIKDCTHTKSERNSDEDSSSCSSIDSSEFSSDEVCYEDDVNEEDIKKLY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :* ***: . *: :: :. *****:******. * . *:*: :. : ::. **: :: . : : : * * :* : :*:* ** * *:.: :: : *:* **.::* * *****:****:*: :******.:*: .*: :.***::**: **::*: : *****.**: :** ** **:.. .:. :: *:* *:* * :* * . : * .* *: * ::* * : :: : ** *:: * * *. :. :: ", "identical_positions": 95, "similar_positions": 89, "identity": "7.0%" }, { "cls_id": "homologset.agr.SGD:S000004830", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3THK7-1", "uniprot_id": "GUAA_MOUSE", "id": "Q3THK7-1", "name": "GMP synthase [glutamine-hydrolyzing]", "aln": "MALCNGDSKPENAGGDLKDGSHHYEGAVVILDAGAQYGKVIDRRVRELFVQSEIFPLETPAFAIKEQGFRAIIISGGPNSVYAEDAPWFDPAIFTIGKPILGICYGMQMMNKVFGGTVHKKSVREDGVFNIS-MDNTCSLFRGLQKEEIVLLTHGDSVDKVADGFKVVARSGN-IVAGIANESKKLYGVQFHPEVGLTENGKVILKNFLYDIAGCSGNFTVQNRELECIREIKEKVG-TSKVLVLLSGGVDSTVCTALLNRALNQDQVIAVHIDNGFMRKRESQSVEEALKK-LGIQVKVINAAHSFYNGTTTLPISDEDRTPRKRISKTLNMTTSPEEKRKIIGDTFVKIANEVIGEMSLK--PEEVFLAQGTLRPDLIESASLVASGKAELIKTHHNDTELIRKLREEGKVIEPLKDFHKDEVRILGRELDLPEELVSRHPFPGPGLAIRVICAEEPYICKDFPETNNILKIVADFSASVKKPHTLLQRVKACTTEEDQEKLMQITSLHSLNAFLLPIKTVGVQGDCRSYSYVCGISSKDEPDWESLIFLARLIPRMCHNINRVVYIFGPPVKEPPTDVTPTFLTTGVLSTLRQADFEAHNILRESGFAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGVPATPG-NEIPVEVVLKMVTEIKKIPGISRIMYDLTSKPPGTTEWE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V7C6-1", "uniprot_id": "GUAA_RAT", "id": "Q4V7C6-1", "name": "GMP synthase [glutamine-hydrolyzing]", "aln": "MALCNGDSKPENAGGDLKDGCHHYEGAVVILDAGAQYGKVIDRRVRELFVQSEIFPLETPAFAIKEQGFRAIIISGGPNSVYAEDAPWFDPAIFTIGKPVLGICYGMQMMNKVFGGTVHKKSVREDGVFNIS-MDNTCSLFRGLQKEEIVLLTHGDSVDKVADGFKVVARSGN-IVAGIANESKKLYGVQFHPEVGLTENGKVILKNFLYDIAGCSGNFTVQNRELECIREIKEKVG-TSKVLVLLSGGVDSTVCTALLNRALNQDQVIAVHIDNGFMRKRESQSVEEALKK-LGIQVKVINAAHSFYNGTTTLPISDEDRTPRKRISKTLNMTTSPEEKRKIIGDTFVKIANEVIGEMSLK--PEEVFLAQGTLRPDLIESASLVASGKAELIKTHHNDTELIRKLREEGKVIEPLKDFHKDEVRILGRELDLPEELVSRHPFPGPGLAIRVICAEEPYICKDFPETNNILKIVADFSASVKKPHTLLQRVKACTTEEDQEKLMEITSQHSLNAFLLPIKTVGVQGDCRSYSYVCGISSKDEPDWESLIFLARLIPRMCHNINRVVYIFGPPVKEPPTDVTPTFLTTGVLSTLRQADFEAHNILRESGYAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGVPATPG-NEIPVEVVLKMVTEIKKIPGISRIMYDLTSKPPGTTEWE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49915-1", "uniprot_id": "GUAA_HUMAN", "id": "P49915-1", "name": "GMP synthase [glutamine-hydrolyzing]", "aln": "MALCNGDSKLENAGGDLKDGHHHYEGAVVILDAGAQYGKVIDRRVRELFVQSEIFPLETPAFAIKEQGFRAIIISGGPNSVYAEDAPWFDPAIFTIGKPVLGICYGMQMMNKVFGGTVHKKSVREDGVFNIS-VDNTCSLFRGLQKEEVVLLTHGDSVDKVADGFKVVARSGN-IVAGIANESKKLYGAQFHPEVGLTENGKVILKNFLYDIAGCSGTFTVQNRELECIREIKERVG-TSKVLVLLSGGVDSTVCTALLNRALNQEQVIAVHIDNGFMRKRESQSVEEALKK-LGIQVKVINAAHSFYNGTTTLPISDEDRTPRKRISKTLNMTTSPEEKRKIIGDTFVKIANEVIGEMNLK--PEEVFLAQGTLRPDLIESASLVASGKAELIKTHHNDTELIRKLREEGKVIEPLKDFHKDEVRILGRELGLPEELVSRHPFPGPGLAIRVICAEEPYICKDFPETNNILKIVADFSASVKKPHTLLQRVKACTTEEDQEKLMQITSLHSLNAFLLPIKTVGVQGDCRSYSYVCGISSKDEPDWESLIFLARLIPRMCHNVNRVVYIFGPPVKEPPTDVTPTFLTTGVLSTLRQADFEAHNILRESGYAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGIPATPG-NEIPVEVVLKMVTEIKKIPGISRIMYDLTSKPPGTTEWE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIE7-1", "uniprot_id": "Q9VIE7_DROME", "id": "Q9VIE7-1", "name": "GMP synthase (glutamine-hydrolyzing)", "aln": "---MNSNIFLGTAENGLR------HDKIVILDAGAQYGKVIDRKVRELFVETDILPLDTPAATIRNNGYRGIIISGGPNSVYAEDAPSYDPDLFKLKIPMLGICYGMQLINKEFGGTVLKKDVREDGQQNIE-IETSCPLFSRLSRTQSVLLTHGDSVERVGENLKIGGWSTNRIVTAIYNEVLRIYGVQFHPEVDLTINGKQMLSNFLYEICELTPNFTMGSRKEECIRYIREKVG-NNKVLLLVSGGVDSSVCAALLRRALYPHQIIAVHVDNGFMRKKESEKVERSLRD-IGIDLIVRKEGYTFLKGTTQVKRPGQYSVVET---PMLCQTYNPEEKRKIIGDIFVKVTNDVVAELKLK--PEEVMLAQGTLRPDLIESASSMVSTNAETIKTHHNDTDLIRELRNAGRVVEPLCDFHKDEVRDLGNDLGLPQELVERQPFPGPGLAIRVLCAEEAYMEKDYSETQVIIRVIVDYKNKLQKNHALINRVTAATSEAEQKDLMRISSNSQIQATLLPIRSVGVQGDKRSYSYVVGLSTSQEPNWQDLLFLAKIIPRILHNVNRVCYIFGEPVQYLVTDITHTTLNTVVLSQLRQADDIANEIIMQAGLYRKISQMPVVLIPVHFDRDPINRTPSCRRSVVLRPFITNDFMTGVPAEPGSVQMPLQVLNQIVRDISKLDGISRVLYDLTAKPPGTTEWE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38625-1", "uniprot_id": "GUAA_YEAST", "id": "P38625-1", "name": "GMP synthase [glutamine-hydrolyzing]", "aln": "---MAAGEQVSNMF-----------DTILVLDFGSQYSHLITRRLREFNIYAEMLPCTQKISELG-WTPKGVILSGGPYSVYAEDAPHVDHAIFDLNVPILGICYGMQELAWINGKQVGRGDKREYGPATLKVIDDSNSLFKGMN-DSTVWMSHGDKLHGLPTGYKTIATSDNSPYCGIVHETKPIYGIQFHPEVTHSTQGKTLLKNFAVDLCHAKQNWTMENFIDTEINRIRKLVGPTAEVIGAVSGGVDSTVASKLMTEAIG-DRFHAILVDNGVLRLNEAANVKKTLVEGLGINLMVVDASEEFLS--------------------KLKGVTDPEKKRKIIGNTFIHVFEREAEKIKPKDGKEIQFLLQGTLYPDVIESISFKGP--SQTIKTHHNVGGLLENMK--LKLIEPLRELFKDEVRHLGELLGIPHDLVWRHPFPGPGIAIRVLG-------------------------EVTKEQVEIARKADNIYIEEIKKAGLYNQISQAFACLLPVKSVGVMGDQRTYDQVIALRAIETTDFMTADWFP------------------------------------------------------------------------FEHSFLKKVAS-------------------------------------RIVNEVDGVARVTYDITSKPPATVEWE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . . :::** *:**.::* *::**: : ::::* : :.:*:**** ******** * :* : *:******** : * * : . ** * .:. :: : .** :. . * ::***.:. : . * . * * .* :* :** ****** : :** :*.** ::. . .:*: . *. *:: ** . :*: :******:*.: *: .*: .:. *: :***.:* .*: .*:.:* . :**:: * . . * . * . .**:******: *::: : ::. * * :* **** **:*** * . :: ****** *:.::: :::*** ::.***** **. *.:*.:** *:******:****: .: * :. : * : :. .. . * ***:::*** ** *:*. * .: : : .:: ::. *::. ::: .* :.:: *::*: **:*:***.*.***", "identical_positions": 173, "similar_positions": 175, "identity": "24.71%" }, { "cls_id": "homologset.agr.SGD:S000004831", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAQ4-1", "uniprot_id": "F1MAQ4_RAT", "id": "F1MAQ4-1", "name": "", "aln": "MDAPEEPQPPVVYTMENKPIVTCAGDQNLFTSIYPTLSQQLPREPMEWRRSYGRAPKMIHLESNFVQFKEELLP--KEGNKALLTFPFLHIYWTECCDTEVYKATVKDDLTKWQNVLKAHSSVD-----WLIVVVENDAKKKNKTNILPRTSIVDKIRNDFCNKQSDRCVVLSDPLKDSSRTQESWNAFLTKLRTLLLMSFTKNLGKFEDDMRTLREKRTEPGWSFCEYFMVQEELAFVFEMLQQFEDALVQYDELDALFSQYVVNFGAGDGANWLTFFCQPVKSWNGLVLRKPIDMEKRELIQKQEATLLDLRSYLFSRQCTLLLFLQRPWEVAQRALELLHSCVQELKLLEVSVPPGALDCWVFLSCLEVLQRIEGCCDRAQIDSNIAHMVGLWSYAMEKLKSLGYLCGLVSEKGPNSEDLNRTVDLLAGLGAE----------------RPETANTAQSPYKKLQEALSSVEAFEKHYLDLSHATIEMYTSIG--RIRSAKLVGKDLAEFYMRKRSPQKAEMYLQGALKNYMAEGWALPVTHTRKQLAECQKHLGQMENYLQTSSLLASDHHLTEEERKHFCQEILSFASQQEDKAGHKVVLPMHSFARLKDLHFDPPNAVVHAGGVLTVEITVCSQMPVPVHVDQIAVNVHFSIEKNNYRKTAEWLTKHKTSNGVITFPAEASLFPAPQNSLPALELSEMLERSPSDNSLNTTGIICRNVHMLLRRQESGSSLEPPSGLALEDGAHVLRCTSVTLQPGANKIVFKTQAKEPGTYTLRQLRASVGP-------VWFVLAHIHPIVQYDVYSQEPQLHVEPLADSLLAGIPQKVKFTVTTGHYTVKDGDSLQLSNVEAMLILCQAENRAVVYSNTREECSSALLRIQSSDKVTSIGLPTAPAYHVIEFELEVLSLPSAPAAVEDSSILGTPELHRKQKDSQRADHCMVTTDHKVSIDCPWSIYSTVIALTFSVPFRTAHSLLSAGTRKYVQVCVQNLSELDFELSDSNLEDKGHATDLRLVPLNTQSQQLIHSKQSVFFVWELTWTQEPP------PPLHCRFSVGFSPASAERLTVSLKPYTYEFQVESFFTLYSVRAEILPASGAEFCKTGSLCSLEVCITRLADLLDVDKDEALVESEDYFSTKLMYEVVDNSSNWAVCGKSCGVIAMPLAAQATHRVHMEVMPLFAGYLPLPDVRLFKYLPHHSAHASQLDADSWIENDSLSVDKHLDDQLDCSSLRSRGSAHSTSSGEHKGLPMPRLQALPAGQVFNSSTGMQILVIPSQDDHVLEVSVT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TLI0-1", "uniprot_id": "TPC10_MOUSE", "id": "Q3TLI0-1", "name": "Trafficking protein particle complex subunit 10", "aln": "MDAPEEPQPPVVYTMENKPIVTCAGDQNLFTSIYPTLSQQLPREPMEWRRSYGRAPKMIHLESNFVQFKEELLP--KEGNKALLTFPFLHIYWTECCDTEVYKATVKDDLTKWQNVLKAHSSVD-----WLIVVVENDAKKKNKTNILPRTSIVDKIRNDFCNKQSDRCVVLSDPLKDSSRTQESWNAFLTKLRTLLLMSFTKNLGKFEDDMRTLREKRTEPGWSFCEYFMVQEELAFVFEMLQQFEDALVQYDELDALFSQYVVNFGAGDGANWLTFFCQPVKSWNGLVLRKPIDMEKRELIQKQEATLLDLRSYLFSRQCTLLLFLQRPWEVAQRALELLHSCVQELKLLEVSVPPGALDCWVFLSCLEVLQRIEGCCDRAQIDSNIAHMVGLWSYAMEKLKSLGYLCGLVSEKGPNSEDLNRTVDLLAGLGAE----------------RPETANTAQSPYKKLQEALSSVEAFEKHYLDLSHATIEMYTSIG--RIRSAKLVGKDLAEFYMRKRSPQKAEMYLQGALKNYLAEGWALPVTHTRKQLAECQKHLGQMENYLQTSSLLASDHHLTEEERKYFCQEILSFASQQEDNPGHKVVLPMQ-FARLKDLHFDPPNAVVHAGGVLTVEITVCSQMPIPVHVDQIAVNVHFSIEKNNYRKTAEWLTKHKTSNGIITFPAEASLFPASQNSLPALELSEMLERSPSDNSLNTTGIICRNVHMLLRRQESGSSLEPPSGLALEDGAHVLRCSSVTLQPGANKIAFKTQAKEPGTYTLRQLRASVGP-------VWFVLAHIHPIVQYDVYSQEPQLHVEPLADSLLAGIPQKVKFTVTTGHYTVKNGDSLQLSNVEAMLILCQAENRAVVYSNSREECSTALLRIQSSDKVTSIGLPTAPAYHVIEFELEVLSLPSAPASGGDTSVPGTPELHRKQKDSQRAGHCMVTTDHKVSIDCPWSIYSTVIALTFSVPFRTEHSLLSAGTRKYVQVCVQNLSELDFELSDSNLEDKGHATDLRLAPLNTQSQQLIHSKQSVFFVWELTWTQEPP------PPLHCQFSVGFSPASEEQLTVSLKPYTYEFQVENFFTLYSVRAEILPASGAEYCKTGSLCSLEVSITRLADLLDVDKDEALVESEDYFSTKLMYEVVDNSSNWAVCGKSCGVIAMPLAAQATHRVHMEVMPLFAGYLPLPDVRLFKYLPHHSAHASQLDADSWIENDSLSVDKHLDDQLDCSSLRSRGSTHSTSSSEHKGLPMPRLQALPAGQVFNSSTGMQVLVIPSQDDHVLEVSVT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48553-1", "uniprot_id": "TPC10_HUMAN", "id": "P48553-1", "name": "Trafficking protein particle complex subunit 10", "aln": "MDASEEPLPPVIYTMENKPIVTCAGDQNLFTSVYPTLSQQLPREPMEWRRSYGRAPKMIHLESNFVQFKEELLP--KEGNKALLTFPFLHIYWTECCDTEVYKATVKDDLTKWQNVLKAHSSVD-----WLIVIVENDAKKKNKTNILPRTSIVDKIRNDFCNKQSDRCVVLSDPLKDSSRTQESWNAFLTKLRTLLLMSFTKNLGKFEDDMRTLREKRTEPGWSFCEYFMVQEELAFVFEMLQQFEDALVQYDELDALFSQYVVNFGAGDGANWLTFFCQPVKSWNGLILRKPIDMEKRESIQRREATLLDLRSYLFSRQCTLLLFLQRPWEVAQRALELLHNCVQELKLLEVSVPPGALDCWVFLSCLEVLQRIEGCCDRAQIDSNIAHTVGLWSYATEKLKSLGYLCGLVSEKGPNSEDLNRTVDLLAGLGAE----------------RPETANTAQSPYKKLKEALSSVEAFEKHYLDLSHATIEMYTSIG--RIRSAKFVGKDLAEFYMRKKAPQKAEIYLQGALKNYLAEGWALPITHTRKQLAECQKHLGQIENYLQTSSLLASDHHLTEEERKHFCQEILDFASQPSDSPGHKIVLPMHSFAQLRDLHFDPSNAVVHVGGVLCVEITMYSQMPVPVHVEQIVVNVHFSIEKNSYRKTAEWLTKHKTSNGIINFPPETAPFPVSQNSLPALELYEMFERSPSDNSLNTTGIICRNVHMLLRRQESSSSLEMPSGVALEEGAHVLRCSHVTLEPGANQITFRTQAKEPGTYTLRQLCASVGS-------VWFVLPHIYPIVQYDVYSQEPQLHVEPLADSLLAGIPQRVKFTVTTGHYTIKNGDSLQLSNAEAMLILCQAESRAVVYSNTREQSSEAALRIQSSDKVTSISLPVAPAYHVIEFELEVLSLPSAPALGGESDMLGMAEPHRKHKDKQRTGRCMVTTDHKVSIDCPWSIYSTVIALTFSVPFRTTHSLLSSGTRKYVQVCVQNLSELDFQLSDSYLVDTGDSTDLQLVPLNTQSQQPIYSKQSVFFVWELKWTEEPP------PSLHCRFSVGFSPASEEQLSISLKPYTYEFKVENFFTLYNVKAEIFPPSGMEYCRTGSLCSLEVLITRLSDLLEVDKDEALTESDEHFSTKLMYEVVDNSSNWAVCGKSCGVISMPVAARATHRVHMEVMPLFAGYLPLPDVRLFKYLPHHSAHSSQLDADSWIENDSLSVDKHGDDQPDSSSLKSRGSVHSACSSEHKGLPMPRLQALPAGQVFNSSSGTQVLVIPSQDDHVLEVSVT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFB7-1", "uniprot_id": "TPC10_DROME", "id": "Q9VFB7-1", "name": "Trafficking protein particle complex subunit 10", "aln": "--------------MQIKPIITYSGSCPLFRSLESQILNAIPLDTCEWRRTFQRPTKHVRLEAQAQQFNVAALEKYKQGDWSILEHPILHIFVTECNDVDTYKATIREAIDIWLKTLTSYGVSD-----WMILLVETLDMRKTKN-FMPRTTVLDKIRLDFGTKNDDRCISVLNPAKFEQKSTESFRCLVQRIRFLMLTSYNRNIVKYEELIRSKREKRNIEGWDFRQYFFMQEDLALIFEKLELPTEALIQYDELDAMFSQFITHTGLNEKQQWLNHFRKPLDAFHGICLTRADKFEMRNKIRDEGVSLLEFRNYLFERQAYLLLTCNDIPEIAKRLLNFLFSTLREVELIKLECQEGALCCWEFVCALEVLQLCEQAMEPNELTC-FQHCAPIWNLAKDKLYELGKLCGLLPGCTPTSEQLHIVVQLSSGIGDAPSEQHQFLQATPQLRDRSPNRKPKKSGAEQLKEALGSNQAFQKLYLELAELAISTYKHVT--RLRSARLVGLDLGNFYCALNEPHKAVGFFTDLLRELKAENWHMLSSQTLLELANCYRKMGDSLAYTKTCSSISCCAELETLVRTFYFDEFLKSLKTLKTTLSAQPSIENANYCVLEDHFRILDIEVVNQKPIIQDDYILVQLKVESLYPRGVVAEN----VKLCYELEASSLELAMENVSLTASPSTVKAKDTSSRLKVSLQLVYKQ-----DNRLHSAAVACDLPKSKQPVRRTSSTKRKLSPSVQADFTNFVQAENIALQPGVNLIEMKAKATRVGCWQFKQLCISMSS-------LEFLSEQLPFMPATFEISTKP-ASATLEFKTLIAGIVQPISLNVSGGSFIFPPDAKITLRCSKNLRIRQARNTDDEAAYNDD----------QSFESTLQVPLVQFKSFEERRIPLEVLTDMPG-------------------------RKVSKHHEHHIALNCPWSRTELPIAVDFQPAMEATCRLHTCGTQKFLQVIMK---GMEAHLLLQHAQVKCDVPGVQLLDLNPESQQPIEIYKSLTVTYLYEIQVEPLKTEHELPVVKVHFVIKYASLSQ---PDVWRTYGCAFDLVDYTTLFKLQAQLEPN---ELCRLRTVCNMNLKITKVHENPYTD---------------LMYEVLNDQNLWAVCGRSAGVVSMKDVD--SHSISLDVMPLSTGFLPMPSIRLSKYT---------------------------------------------AGGKSKTDGHSKVHPFPPGQVYNSTKSMQIHVIASVAGDQ------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03660-1", "uniprot_id": "TR130_YEAST", "id": "Q03660-1", "name": "Trafficking protein particle complex II-specific subunit 130", "aln": "---------MDKEIYCGSVPVSYFDPFDLFESLRPEFQQILPLDNIHWKAFDGTVRTVNRLPIELIPEGRGEAD------KSNDEQPFIRFLIVNCISIDQYRAKVRPLVRQWLPNLESVSSSTGEKMIYKPIILLYANSEVVDSNLFKSVSLMEKFGKDFPHVQT---LEVRSVYRSPKERQEFWNQFSQKIKASVLSIFQKRLTHLQHSLANLQK-----GNNFEEQLLTREKLYELYVVFNILEDASLELQKIKKEILRRNMNMPDGKLQVPFESSSKSDESLGSIIIEGTLDK-------------FQLHKYFFIRRLRLLKLEDQTLTAFVGAFQLIKNFIESISIEYRKSVRLLEFKHYFITSMLSYFEFENVSNPLLCEIKAELLMLKRDNWVQGVMATSGYR-LMDKNYPNSD--------------------------------------VKYKFDLLKETFVDETVFQENFLTLTKEILSLFNKCEGKRQRIVDILSIEIGLLYYQGKKYEEAVSLFLSCYEYYTQTNWNSIGLKILQVFIDSLSHCPKLDVLQIDGESVSASAVLTN-----AFLNILKLCKDNDSK--------EIWWKKFMDLQMKNNIHLMYPLDGLFEVTLNSKVHLARANVSAIEVNLKSYGFPEDISTKTMRLSLKNMGGDVIVFGASDFLLKKGENKLILECRDIMYG----EFSLLSFEIIVEGITFVKEFPENQDEFIVVPEIYCKESTKVLVKQAHNLNLGEYALELKSVQSDALESLQVEVEVQKNIGNMKNLPVSFSMDEIQARKRYNTPFENVRLEYYLLDQITAFDLIIKTSFTKKNDQGTFGETKKVRIQCYLQLSVSVEDIFKKDIFFFKFLLNSSVR---EEPVILYSSELSAPDTRNDYNIRGDYIATTPALITFDG--------------NESFINCYEITANNNFDSKDIFNLKVRYNTLKEQLDCFITDAVLIEGDVEWFILFEKWKTFWELEILKKLKYDYDAFKENRIIRLLKTSIDLNKTKSKIRNLCIEKAVLDKILICLN--KVSRGIAVCNTDMDEYVRNLVPKQLTVPVQLPGFEQFFHVQFEQMETSHDALHDTIATIGNSLSYTVIVENLSGQWGQDVIDDGG-----YIFEILS-SNEWLIHGQKRCAIKEKRKE-----FEVHLIPLKKGYLNFPRVEITNIN-------------------------------------------------GKSCRVDHSNAFESILIF------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: . ** *: . : : :* : .*: . :* : : *:::: .:* . : *:*.:: : * * : . : ::: . .. :: .::::*: ** : : : . : .. * :. : ::: :* : :.: : :. : . :: * .* : :: :*.* :: :: :* :: :::. : : : .. : :. .: .: : . . ::::.*:* *: ** : :::: . :..:.: . *: .: * : . : : . *: *.*: : . *:*:: . .*:: :* *:. :. :. * * . ::. ::. :* . .:* : . . .* : : :. : . . ::. * ::*. . . . : : * :: : . : .: : * . .: . .. : * : : .. . . : ::.: *: * : ::: . :: . . : * .: : . .: .:. . . . .: : : : :. . * : . .: : :: .. :::. . :. :: . : * ::. : : : .: . :: * * : ..: : : : : : . : ..: .: :: :: : : . .: * : : : ::*::. .. * : *:. .: . :.::** *:* :* :.: : * : :.: . :: ", "identical_positions": 64, "similar_positions": 329, "identity": "4.93%" }, { "cls_id": "homologset.agr.SGD:S000004834", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZDC2-1", "uniprot_id": "D3ZDC2_RAT", "id": "D3ZDC2-1", "name": "Large neutral amino acids transporter small subunit 4", "aln": "-------------------------------------------------------MAPTLATAHRRRWWMACTAVLENLLFSAVLLGWGSLLIMLKSEGFYSYLCTKPENVTNGTVESTAEPEHEEVSLVNGWLSCKAQDEILNLAFTVGSFLLSAITLPLGIIMDKYGPRKLRLLGSACFAVSCLLIAYGASNPDSLSVLIFIALALNGFGGMCMTFTSLTLPNMFGDLRSTFIALMIGSYASSAVTFPGIKLIYDAGASFIVILVVWAGCSGLVFLNCFFNWPLEPFPGPEDMDYSVKIKFSWLGFDHKITGKQFYKQVTTVGRRLSVGSSMRTAKEQAALQEGHKLCLSTVDLEVKCQPDAA------AAPSFMHSVFSPILLLSLVTMCVTQLRLIFYMGAMNSILEFLVSGDQK------------TVALYTSIFGALQLLCLLTAPVIGYIMDWRLKECEDTSEEPEE------KDGAQG--EKKQK-RDRQIQKITNAMRAFAFTNVLLVGFGVTCLIP-NLPLQIFSFVLHTIVRGFIHSAVGGLYAAVYPSTQFGSLTGLQSLVSALFALLQQPLFLAMMGPLGGDPLWVNVGLLVVSMLGFCLPLYLICYRRQLERQLQQRREDSKLFLKINGSSNREAFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CGA3-1", "uniprot_id": "LAT4_MOUSE", "id": "Q8CGA3-1", "name": "Large neutral amino acids transporter small subunit 4", "aln": "-------------------------------------------------------MAPTLATAHRRRWWMACTAVLENLLFSAVLLGWGSLLIMLKSEGFYSYLCTKPENVTNSTVGGSAEPEPEELSLVNGWLSCKAQDEILNLAFTVGSFLLSAITLPLGIIMDKYGPRKLRLLGSACFAVSCLLIAYGASNPDSLSVLIFIALALNGFGGMCMTFTSLTLPNMFGDLRSTFIALMIGSYASSAVTFPGIKLIYDAGASFIGILVVWAGCSGLVFFNCFFNWPLEPFPGPEDMDYSVKIKFSWLGFDHKITGKQFYKQVTTVGRRLSVGSSMRTAKEQAALQEGHKLCLSTVDLEVKCQPDAA------AAPSFMHSVFSPLLVLSLVTMCVTQLRLIFYMGAMNSILEFLVRGDQK------------TVALYTSIFGALQLLCLLTAPVIGYIMDWKLKECEDTSEEPEE------KEGTQG--EKKQK-RDRQIQKVTNAMRAFAFTNVLLVGFGVTCLIP-NLPLQIFSFVLHTIVRGFIHSAVGGLYAAVYPSTQFGSLTGLQSLVSALFALLQQPLYLAMMGPLGGDPLWVNVGLLAMSMLGFCLPLYLICYRRQLERQLQQKREDSKLFLKINGSSNREAFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N370-1", "uniprot_id": "LAT4_HUMAN", "id": "Q8N370-1", "name": "Large neutral amino acids transporter small subunit 4", "aln": "-------------------------------------------------------MAPTLATAHRRRWWMACTAVLENLLFSAVLLGWGSLLIMLKSEGFYSYLCTEPENVTNGTVGGTAEPGHEEVSWMNGWLSCQAQDEMLNLAFTVGSFLLSAITLPLGIVMDKYGPRKLRLLGSACFAVSCLLIAYGASKPNALSVLIFIALALNGFGGMCMTFTSLTLPNMFGDLRSTFIALMIGSYASSAVTFPGIKLIYDAGVSFIVVLVVWAGCSGLVFLNCFFNWPLEPFPGPEDMDYSVKIKFSWLGFDHKITGKQFYKQVTTVGRRLSVGSSMRSAKEQVALQEGHKLCLSTVDLEVKCQPDAA------VAPSFMHSVFSPILLLSLVTMCVTQLRLIFYMGAMNNILKFLVSGDQK------------TVGLYTSIFGVLQLLCLLTAPVIGYIMDWRLKECEDASEEPEE------KDANQG--EKKKKKRDRQIQKITNAMRAFAFTNLLLVGFGVTCLIP-NLPLQILSFILHTIVRGFIHSAVGGLYAAVYPSTQFGSLTGLQSLISALFALLQQPLFLAMMGPLQGDPLWVNVGLLLLSLLGFCLPLYLICYRRQLERQLQQRQEDDKLFLKINGSSNQEAFV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BSM7-1", "uniprot_id": "LAT3_MOUSE", "id": "Q8BSM7-1", "name": "Large neutral amino acids transporter small subunit 3", "aln": "-------------------------------------------------------MAPTLKQAYRRRWWMACTAVVENLFFSAVLLGWASLLIMLKKEGFYSSLCP-AENRTNTTQDEQH-----------QWTSCDQQEKMLNLGFTIGSFLLSATTLPLGILMDRFGPRPLRLVGSACFAASCTLMALASRDTEVLSPLIFLALSLNGFAGICLTFTSLTLPNMFGNLRSTFMALMIGSYASSAITFPGIKLIYDAGVPFTVIMFTWSGLACLIFLNCALNWPAEAFPAPEEVDYTKKIKLIGLALDHKVTGDRFYTHVTIVGQRLSQ--------KSPSLEEGADAFISSPDIPGTSEETPE------KSVPFRKSLCSPIFLWSLVTMGMTQLRVIFYMGAMNKILEFIVTGGKERETNEQRQKVEETVEFYSSIFGVMQLLCLLTCPLIGYIMDWRIKDCVDAPTEGTLNENASFGDARDGASTKFTRPRYRKVQKLTNAINAFTLTNILLVGFGIACLIK-NLHLQLLAFVLHTIVRGFFHSACGGLYAAVFPSNHFGTLTGLQSLISAVFALLQQLLFMAMVGPLHGDPFWVNLGLLLLSFLGFLLPSYLYYYRSRLQREYATNLVDP---QKVLNTSKVAT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AC62-1", "uniprot_id": "A0A8I6AC62_RAT", "id": "A0A8I6AC62-1", "name": "", "aln": "-------------------------------------------------------MAPTLKQAYRRRWWMACTAVVENLFFSAVLLGWASLLIMLKKEGFYSSLCP-AENRTNTTQDEQ------------QWISCDQQEEMLNLGFTIGSFLLSATTLPLGILMDRFGPRPLRLVGSACFAASCTLMALASRDTEVLSPLIFLALSLNGFAGICLTFTSLTLPNMFGNLRSTFMALMIGSYASSAITFPGIKLIYDAGVSFMVIMFTWSGLACLIFLNCALNWPAEAFPAPEEVDYTKKIKLIGLALDHKVTGDRFYTHVTIVGQRLSQ--------KTPSLEEGTDGFISSSDIPGTSEKTPE------KSVPFRKSLCSPIFLWSLVTMGMTQLRVIFYMGAMNKILEFLVTGGKECETNEQRQKVEETVEFYSSIFGVMQLLCLLTCPLIGYIMDWRIKDCVDDPTEGTLNESASFGDARDGTITKFTKPRYRKIQKLTNAINAFTLTNILLVGFGITCLIK-NLHLQLVAFVLHTVVRGFFHSACGGLYAAVFPSNHFGTLTGLQSLISAVFALLQQLLFMAMVGPLHGDPFWVNLGLLILSLLGFLLPSYLYYYRSRLEREYATNLLDP---QKVLNTSKVAT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75387-1", "uniprot_id": "LAT3_HUMAN", "id": "O75387-1", "name": "Large neutral amino acids transporter small subunit 3", "aln": "-------------------------------------------------------MAPTLQQAYRRRWWMACTAVLENLFFSAVLLGWGSLLIILKNEGFYSSTCP-AESSTNTTQDEQR-----------RWPGCDQQDEMLNLGFTIGSFVLSATTLPLGILMDRFGPRPVRLVGSACFTASCTLMALASRDVEALSPLIFLALSLNGFGGICLTFTSLTLPNMFGNLRSTLMALMIGSYASSAITFPGIKLIYDAGVAFVVIMFTWSGLACLIFLNCTLNWPIEAFPAPEEVNYTKKIKLSGLALDHKVTGDLFYTHVTTMGQRLSQ--------KAPSLEDGSDAFMSPQDVRGTSENLPE------RSVPLRKSLCSPTFLWSLLTMGMTQLRIIFYMAAVNKMLEYLVTGGQEHETNEQQQKVAETVGFYSSVFGAMQLLCLLTCPLIGYIMDWRIKDCVDAPTQGTV-----LGDARDGVATKSIRPRYCKIQKLTNAISAFTLTNLLLVGFGITCLIN-NLHLQFVTFVLHTIVRGFFHSACGSLYAAVFPSNHFGTLTGLQSLISAVFALLQQPLFMAMVGPLKGEPFWVNLGLLLFSLLGFLLPSYLFYYRARLQQEYAANGMGP---LKVLSGSEVTA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2AVZ9-1", "uniprot_id": "S43A3_MOUSE", "id": "A2AVZ9-1", "name": "Equilibrative nucleobase transporter 1", "aln": "----------------------------------------------------------MASKGLPLYLATLLTGLLECIGFAGVLFGWTSLLFVFKAENYFSEPCEQDCLLQSNVTGPSD---------------LKAQDEKFSLIFTLASFMNNFMTFPTGYIFDRFKTTVARLIAIFFYTCATIIIAFTS---ANTAMLLFLAMPMLAVGGILFLITNLQIGNLFGKHRSTIITLYNGAFDSSSAVFLVIKLLYEQGISLRSSFIFMSVCSVWHIARTFLLMPKGHIPYPLPPNYSYGLCSRFGASKKENKAAEHETKELRSKECLPP--------KEENSGPEQQQQQEQQQQQQQQQEQHE-------QHSFRRCALSRRFILHVVWLSIIQLWHYLFIGTLNSLLTKLSGGDKV------------EVSAYTNAFAITQFFGVLCAPWNGLLMDRLKQKYQKAAKRTGS---------------------SSEAVALCSMVPSLALTSLLSLGFALCASIP-VMQLQYATFILQVVSRSFLYGCNAAFLTLAFPSEHFGKLFGLVMALSAIVSLLQFPLFKVSPESN-----AVYVSMGLAIFLTLVHPFLVYRECRAEKTKSSVDA-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LPJ3-1", "uniprot_id": "A0ABK0LPJ3_RAT", "id": "A0ABK0LPJ3-1", "name": "", "aln": "MAQGSRQTDPRHFLLNPETVGTRGLIEVECLPKEISYTPLPVVSEVQDRICGPTSPQTMASQ-LPLYLATFLTGLLECIGFAGVLFGWTSLLFVFKAENYFLKPCEQDCVLGGNTTGLPD---------------LKAQDEKFSLIFTLASFMNNFMTFPTGYIFDRFKTAVARLLAIFFYTCATLIIAFTS---ADTAMLLFLAMPMLAVGGILFLITNLQIGNLFGKHRSTIITFYNGAFDSSSAVFLIIKLLYEQGISLRHSFIFLSVCSAWHVGRTFLLMPRGHIPYPLPPNYSYGLCSRFCTRKEENEAAEHETKELQSRECQSP--------KEENSGPEQQQQQQQQQQQQQQQQQ---------QHSFRRCVFSHRFILHVVWLSIIQLWHYLFIGTLNSLLTKLAGEDSV------------KVSAYTNAFAITQFFGVLCAPWNGLLMDCLKQKYQKEAKRTGL---------------------SSEAVALCSMVPSLALTSLLSLGFTLCASIP-VIELQYATFILQVVSRSFLYGCNAAFLTLAFPSEHFGKLFGLVMALSAIVSLLQFPLFKVSPESK-----AVYVSMGLAIFLTLVHPFLVYRECRVEKTKPSVDA-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NBI5-1", "uniprot_id": "S43A3_HUMAN", "id": "Q8NBI5-1", "name": "Equilibrative nucleobase transporter 1", "aln": "----------------------------------------------------------MAGQGLPLHVATLLTGLLECLGFAGVLFGWPSLVFVFKNEDYFKDLCGPDAGPIGNATGQAD---------------CKAQDERFSLIFTLGSFMNNFMTFPTGYIFDRFKTTVARLIAIFFYTTATLIIAFTS---AGSAVLLFLAMPMLTIGGILFLITNLQIGNLFGQHRSTIITLYNGAFDSSSAVFLIIKLLYEKGISLRASFIFISVCSTWHVARTFLLMPRGHIPYPLPPNYSYGLCPGNGTTKEEKETAEHENRELQSKEFLSA--------KEETPGAGQKQELR----------------------SFWSYAFSRRFAWHLVWLSVIQLWHYLFIGTLNSLLTNMAGGDMA------------RVSTYTNAFAFTQ-FGVLCAPWNGLLMDRLKQKYQKEARKTGS---------------------STLAVALCSTVPSLALTSLLCLGFALCASVP-ILPLQYLTFILQVISRSFLYGSNAAFLTLAFPSEHFGKLFGLVMALSAVVSLLQFPIFTLIKGSLQNDPFYVNVMFMLAILLTFFHPFLVYRECRTWKESPSAIA-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6L3-1", "uniprot_id": "A0ACD6B6L3_DANRE", "id": "A0ACD6B6L3-1", "name": "", "aln": "-----------------------------------------------------MFGCQGD-GLRVRSWFTLISGLVECLGFAGAVFGWASLVFVLKNEGYFSSLCVNTTING---TAVED---------------CSRQDEQFSLIFTIASFMNNFLTLPNGFLFDRFGTTVARLLGISVYSTGMLLIAFST---TASSILLFPALSFISVGGILFLMTNIQVGNLFGTHRSTIITLYNGAFDSSSAVFLIIKLLFEDGVSLRGCFLFMACCSVIHLFRTFVLMPRTHIPYPLPENYTYGIN---CGGTQDYTIAKVEEKNIQTSQAE----------EEEAFTETSPQGQNTSKMER----------------SFKSCFLSWFFLWHLLWLSVMQLRHYLFIGTLNPMLNHLTAGDPS------------LVSRYTNAFAFTQLCGILCAPWNGLLMDRHKGK----QREPGQ---------------------SEQEADLKAAILSLSLTALQCVLFSVCAATP-ILPLQYLTFILQVLNRSFLYGGNAAFISVAFPSVHFGKLYGTVMALSAVVSLLQYPCFALIKGTLGGDPLYVNIGLTVLSLLAFVNPLYVYLHCRRQATQRRAAKKTSSS--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F4C3-1", "uniprot_id": "E7F4C3_DANRE", "id": "E7F4C3-1", "name": "", "aln": "-----------------------------------------------------MMAYKGSSGKVVRYKLTLATGLLECLCFAGVVFGWASLVFVLKTDGYFGDLCSNATDAGG--EFSSD---------------CGLQDEHFSLVFTVASFMNNFLTLPNGFLYDHFGTMATRLLAIFLYTTGTLIVAFSN---KALSVLLFPALSFIAVGGILFLMTNMQVGNLFGSHRSTIITVYNGAFDSSSVIFLIIKVLYEKGVSLRSSFLFLSACNLIHLIRTLFLMPKSHIPYPIPQDYQYGIS---CAKSNSYNVEEYEAKREASSDRSRR--------AEEELLETDSIKLTDNPEKD----------------SFRSCVLSWFFLWHLVWLSVMQLRHYFFIGTLNPMLNRLANQNPV------------TVSEYTNAFAFTQFCGVLCAPWNGLLMDRHKRK----PLDPDV---------------------SEREADLRSSILSLLLTSLQCFLFSICASIP-FLPLQYLTFILQVLNRSFLYGGNAAFISIAFPARHFGKLYGLVMSLSAVVSLLQYPCFALNK-ALGGDPLYVNILLTILTLLAFIHPVYVFLHCRELAKHRENSRTLEASIQETSMY-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04991-1", "uniprot_id": "FMP42_YEAST", "id": "Q04991-1", "name": "Protein FMP42", "aln": "-----------------------------------------------------------MTSTRTLRYAQVACACIWCLFSAGIIFGFAALKPILISEGVYHELCDPKDGDR---------------------LLCTAQDLKLNFIFALSATVTNIMALPVGKILDMYGPRVCGIIGSCLLFLASGNFISAK-HLVSLWDPYLVGYTLLAVAGPFVFISCFQLANSFPQRSGTVLALLTGSFDSSSALFLLYRLLYQNWFPTLNVSRFFTLYLIVPVFILACQLTIMPHSSYKTVNHIAKIAVEGLDENGRLIEGDTGSGIIPDEQERQSLIAIEREEDSIPSRPQRRKSVLETYVEDKLQKKSGGIFGVLHGKSAYEQIKSPWFYLMLLFALVAMLRINYFIATVRTQEEYLLNDPDL------------ALKLNSIFDMLLPLGGAVSIPFIGLLLDH------------------------------------------TDTLSTLTILFTTSTAIGVFGLIPNSFTWNLIGIVLLVVYRPFYYTVVSDYSSKVFGFDTFGTVYGLLSCICGIFNMSQNLLDKWTHTTFNMNPFPINLTLVILTVV-FSLTLTFYIRSQILPKPVNERGLSSNYQTI-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : :. ::*: :* :: :. : * *: :.: *::.: : . ::* * : * : . ::. . . : . .: ..* . :: : : * * .*.::. *:: **: * ::::: . : . . . :: : . * : :: : * ::.::. : : : : * * ::* : :: : : : : : ::* .: * * : . : .: **.: * :..:. : * . : : : .: : . . ", "identical_positions": 28, "similar_positions": 117, "identity": "4.3%" }, { "cls_id": "homologset.agr.SGD:S000004835", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8WZ82-1", "uniprot_id": "OVCA2_HUMAN", "id": "Q8WZ82-1", "name": "Esterase OVCA2", "aln": "------------------------MAAQRPLRVLCLAGFRQSERGFREKTGALRKALRGR-AELVCLSGPHPVPDPPGPE-GARSDFGSCPP-EEQPRGWWFSEQEADVFSALEEPAVCRGLEESLGMVAQALNRLGPFDGLLGFSQGAALAALVCALG----QAGDPRFPLPRFILLVSGFCPRGIGFKESILQRPLSLPSLHVFGDTDKVIPSQESVQLASQFPG--AITLTHSGGHFIPAAAPQRQAYLKFLD-QFAE---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D7E3-1", "uniprot_id": "OVCA2_MOUSE", "id": "Q9D7E3-1", "name": "Esterase OVCA2", "aln": "------------------------MAARQTLRVLCLAGFRQSERGFREKTGALRKTLRGR-AELVCLSGPHPVPEAAAPE-GSCPDSGPCSP-EEQPRGWWFSEEEADVFSALEESTVCRGLQEALETVARALDTLGPFDGLLGFSQGAALAAYVCALG----QAGDPRFPLPRFIILVSGFCPR--GLKEPILQSPMSLPSLHVFGDTDRVIPSQESMQLASRFLG--AVTLTHSGGHFIPAAASQRQAYLKFLD-QFAE---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q503Y4-1", "uniprot_id": "OVCA2_DANRE", "id": "Q503Y4-1", "name": "Esterase OVCA2", "aln": "------------------------MSA-VPLRILCIHGYRQNGNSFREKTGALRKLLKKQ-VELVFISAPHQVPAIQEENCGTNQQSQTVSVGDEDQRGWWFSDVQARSFNAKQDCESSLGLEESIEAVKAALKDLGPFSGILGFSQGAALVAMLCALQE---QKLEPDFNF-RFAILVAGFRSACLEHQRFYEGPVITIPSLHVFGQDDRVIPEEMSRDLLPAFDG--AQVLLHPGGHFVPAASSHRQTYQDFLK-RFQ----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDL1-1", "uniprot_id": "LOVG_DROME", "id": "Q9VDL1-1", "name": "Esterase CG5412", "aln": "MTNNDAAVEAAGSSRASSSKQQLKLEITEKVRVLCLHGYRQNGEAFKNKLGSFRKFANKY-AEFVFITAPHVAKALESAA-------EPVPE----QRSWWANK-DDGSFKGTNKGGPAFGFQESLRCVEEAWRTQGPFQGLLGFSQGACFVGLICGLAK---KKLTS--IRPEFAVLASGFLSGSLVHMSAYEE-AISIPTLHIYGQTDEIIPKEMSESLAARFKN--AEVLEHSGGHYFPATAQQKQTFINFFQDRLQEYLEHEELQQSGNASFVDSGAEDDNDAEVAAMTAELDESD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05015-1", "uniprot_id": "FSH2_YEAST", "id": "Q05015-1", "name": "Family of serine hydrolases 2", "aln": "----------------------------MTKNVLMLHGLAQSGDYFASKTKGFRAEMEKLGYKLYYPTAPNEFPPADVPD--------FLGEVIADAPGDGENTGVLAWLENDPSTGGYFIPQTTIDYLHNYVLENGPFAGIVGFSQGAGVAGYLATDFNGLLGLTTEEQPPLEFFMAVSGFRFQPQQYQEQYDLHPISVPSLHVQGELDTITEPAKVQGLYNSCTEDSRTLLMHSGGHFVPNSRGFVRKVAQWLQ-QLT----------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:* : * *. * .* .:* . :: :.*: . . :. . : :: : *** *::****** ... :. .* : .:** :::*:**: *: * : * * *.***:.* : : .::. :: ", "identical_positions": 32, "similar_positions": 51, "identity": "10.67%" }, { "cls_id": "homologset.agr.SGD:S000004836", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1AY15-1", "uniprot_id": "UBP51_MOUSE", "id": "B1AY15-1", "name": "Ubiquitin carboxyl-terminal hydrolase 51", "aln": "----------------------------------------MRGT------QGAQEMKPELWPEPKPTS-ENLTSRGSGSYEKVLPSIPAACHTSSSSVCPRRKPRPRPQPRSRSRGGRGLKAPPPPPAKPPPPPPAPPPPPLPKQRSVAWRNSRRRSRPGPRPQTRKSYSSDHGSSRDSDGSENSLLEVGSNKGPTGCCHVESFKVAKNWQRNLRMIYQRFIWSGTPETRKRKAKSCICQICSTHKNRLHSCLSCVFFGCFTDKHIHIHAETTQHNLAVDLCHGVIYCFMCRDYVYDKDIEKIAKE-TKEKILGLLSSPTGDASYQQLMASEVEENQLTCESKDQETSLVKPKKKRRKKTMYYTVGFRGLINLGNTCFMNCIVQVLTHIPLLKEFFLSNKHK---------------CMMTSPSLCLVCEMSLLFQAMYSGNQSPHIPYK------------LLHLIWIHAEHLAGYRQQDAQEFLIAILDVLHRHSRDDGIDQEGN--------------------SNCCNCIIDHIFTGSLQSDLTCQVCHGVS-TTIDPCWDISLDLPGPYT------PGRASSSTSSRDGQKPRVISLTDCLKWFTRPEDLGSSAKIKCSQCQSYQESTKQLTMKKLPIVACFHLKRFEHLGK-QRRKINSFISFPLE-LDMTPFLASTKESIMK--GQPLTECVPSENKYSLFAVINHHGT-LESGHYTSFVRQEKDQWFSCDDAVVTKATMEELLNSEGYLLFYHRQDIEKE------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZUR6-1", "uniprot_id": "D3ZUR6_RAT", "id": "D3ZUR6-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "MAHVREASRSSRSVACWSSGGGRGACLEQAAENASRMEQTMRGT------QGAQEMKPELWPEPKPTS-ENLTSRGSGSDEKVLPSIPAACHTSSSSVCPRRKPRPRPQPRSRSRGGRGLKAPPPPPAKPPPPPPAPPPPPLPKPRPVAWRNSRRRPRPAPRPQTRKSYPSDPGCSGDSDGTENRLLEVGFDKGPTGCSHVEIFKVAKNWRRNLRMIYQRFIWSGTPETRKRKAKTCICRVCSTHKNRLHSCLSCVFFGCFTEKHIHIHAETKQHNLAVDLYHGVIYCFMCKDYVYDKDIEKIAKE-TKEKILGLLMSTAGDMSYQQLMASEVEENQSICESKEQETSLVKPKKKRRKKTVYYTVGLRGLINLGNTCFMNCIVQALTRIPLLKEFFLSDKHK---------------CMMTSPSLCLVCEMSSLFQAMYSGNQSPHIPYK------------LLHLIWIHAEHLAGYRQQDAHEFLIAILDVLHRHSRDDGIEQEGN--------------------LNHCNCIIDYIFTGGLQSDVTCQVCHGVS-TTIDPCWDISLDLPVSYT------PGRAGST-----GQKPRVISLTDCLKWFTRPEDLGSSAKIKCSRCQSYQQSTKQLTMKKLPIVACFHLKRFEHLGK-QRRKINTFISFPLE-LDMTPFLASTKESIMK--GQPLTECVPIENKYSLFAVINHHGT-LESGHYTSFVRQEKDQWFSCDDAVVTKATMEELLYSEGYLLFYHRQDIEKE------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q70EK9-1", "uniprot_id": "UBP51_HUMAN", "id": "Q70EK9-1", "name": "Ubiquitin carboxyl-terminal hydrolase 51", "aln": "MAQVRETSLPSGSGVRWISGGGGGASPEEAVEKAGKMEEAAAGATKASSRREAEEMKLEPLQEREPAPEENLTWSSSGGDEKVLPSIPLRCHSSSSPVCPRRKPRPRPQPRARSRSQPGLSAPPPPPARPPPPPP-PPPPPAPRPR--AWRGSRRRSRPGSRPQTRRSCSGDLDGSGDPGGLGDWLLEVEFGQGPTGCSHVESFKVGKNWQKNLRLIYQRFVWSGTPETRKRKAKSCICHVCSTHMNRLHSCLSCVFFGCFTEKHIHKHAETKQHHLAVDLYHGVIYCFMCKDYVYDKDIEQIAKE-TKEKILRLLTSTSTDVSHQQFMTSGFEDKQSTCETKEQEPKLVKPKKKRRKKSVY-TVGLRGLINLGNTCFMNCIVQALTHIPLLKDFFLSDKHK---------------CIMTSPSLCLVCEMSSLFHAMYSGSRTPHIPYK------------LLHLIWIHAEHLAGYRQQDAHEFLIAILDVLHRHSKDDSGGQEANN-------------------PNCCNCIIDQIFTGGLQSDVTCQACHSVS-TTIDPCWDISLDLPGSCATFDSQNPERADSTVS-RDDHIPGIPSLTDCLQWFTRPEHLGSSAKIKCNSCQSYQESTKQLTMKKLPIVACFHLKRFEHVGK-QRRKINTFISFPLE-LDMTPFLASTKESRMKE-GQPPTDCVPNENKYSLFAVINHHGT-LESGHYTSFIRQQKDQWFSCDDAIITKATIEDLLYSEGYLLFYHKQGLEKD------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5DU02-1", "uniprot_id": "UBP22_MOUSE", "id": "Q5DU02-1", "name": "Ubiquitin carboxyl-terminal hydrolase 22", "aln": "-----------------------------------------------------------------------------------------------------------------------MVARPEPEVEA--------------------------------------------------------MDAELAVPPPGCSHLGSFKVDN-WKQNLRAIYQCFVWSGTAEARKRKAKSCVCHVCGIHLNRLHSCLYCVFFGCFTKKHIHDHAKSKRHNLAIDLMYGGIYCFLCQDYIYDKDIEIIAKE-EQRKAWKMQG---------------VGEKFSTWEPTKRELELLKHNPKRRKITSNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHR---------------CEMQSPSSCLVCEMSSLFQEFYSGHRSPHIPYK------------LLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDNGKKANN-------------------PNHCNCIIDQIFTGGLQSDVTCQVCHGVS-TTIDPFWDISLDLPGSSTPFWPLSPGSEGSVVNG-ESHASGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAK-LRRKITTYVSFPLE-LDMTPFMASSKESRMNGQYQQPLDSLNNDNKYSLFAVVNHQGT-LESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLDSEGYLLFYHKQFLEYE------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZTX7-1", "uniprot_id": "D3ZTX7_RAT", "id": "D3ZTX7-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "---------------------------------------------------------------------MSICKRRCVDRGMYCGTLCDTLQLACFVLAALASSSPPSPPAPRARALPTMVARPEPEVEA--------------------------------------------------------MDAELAVAPPGCSHLGSFKVDN-WKQNLRAIYQCFVWSGTAEARKRKAKSCVCHVCGIHLNRLHSCLYCVFFGCFTKKHIHDHAKSKRHNLAIDLMYGGIYCFLCQDYIYDKDIEIIAKE-EQRKAWKMQG---------------VGEKFSTWEPTKRELELLKHNPKRRKITSNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHR---------------CEMQSPSSCLVCEMSSLFQEFYSGHRSPHIPYK------------LLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDNGKKANN-------------------PNHCNCIIDQIFTGGLQSDVTCQVCHGVS-TTIDPFWDISLDLPGSSTPFWPLSPGSEGSVVNG-ESHASGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAK-LRRKITTYVSFPLE-LDMTPFMASSKESRMNGQYQQPLDSLNNDNKYSLFAVVNHQGT-LESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLDSEGYLLFYHKQFLEYE------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UPT9-1", "uniprot_id": "UBP22_HUMAN", "id": "Q9UPT9-1", "name": "Ubiquitin carboxyl-terminal hydrolase 22", "aln": "-----------------------------------------------------------------------------------------------------------------------MVSRPEPEGEA--------------------------------------------------------MDAELAVAPPGCSHLGSFKVDN-WKQNLRAIYQCFVWSGTAEARKRKAKSCICHVCGVHLNRLHSCLYCVFFGCFTKKHIHEHAKAKRHNLAIDLMYGGIYCFLCQDYIYDKDMEIIAKE-EQRKAWKMQG---------------VGEKFSTWEPTKRELELLKHNPKRRKITSNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHR---------------CEMQSPSSCLVCEMSSLFQEFYSGHRSPHIPYK------------LLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDNGKKANN-------------------PNHCNCIIDQIFTGGLQSDVTCQVCHGVS-TTIDPFWDISLDLPGSSTPFWPLSPGSEGNVVNG-ESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAK-LRRKITTYVSFPLE-LDMTPFMASSKESRMNGQYQQPTDSLNNDNKYSLFAVVNHQGT-LESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLDSEGYLLFYHKQFLEYE------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6H8I0-1", "uniprot_id": "UBP22_DANRE", "id": "A6H8I0-1", "name": "Ubiquitin carboxyl-terminal hydrolase 22", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPAGCSHVNGFKVDN-WKQNLRVIYQCFVWSGSAETRKRKAKSCICHMCGAHLNRLHSCLHCVFFGCFSKKHIHEHAKNKRHNLAIDLLYGGIYCFVCQDYIYDKDMEQIAKE-EQRKAWKLQG---------------IGEKYSMWEPTKRELELLRHNPKRRKITANCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHK---------------CEMQS-NSCLVCEMSQLFQEFYSGHRSPHIPFR------------LLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCK-DDNGKKANN-------------------PNHCNCIIDQIFTGGLQSDVTCQVCHGVS-TTIDPFWDISLDLPGSSTPFWPLSPGSDGSVVNG-DSHPSGATTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKRLPIVACFHLKRFEHSAK-LRRKITTYVSFPLE-LDMTPFMASSKESRMNGQYQQPVDSLNNDNKYSLFAVVNHQGT-LESGHYTTFIRQHKDQWFKCDDAIITKASIKDVLDSEGYLLFYHKQFLEYE------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8CEG8-1", "uniprot_id": "UBP27_MOUSE", "id": "Q8CEG8-1", "name": "Ubiquitin carboxyl-terminal hydrolase 27", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCKDYVYDIDIEQIAKE-EQGEALKLQASTSTEVSQQQCSVPGLGEKYPTWETTKPELELLGHNPRRRRIASSFTIGLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHR---------------CEMPSPELCLVCEMSSLFRELYSGNPSPHVPYK------------LLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHCKGDDVGKVASN-------------------PNHCNCIIDQIFTGGLQSDVTCQACHGVS-TTIDPCWDISLDLPGSCTSFWPMSPGRE-SSLNG-ESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMKKLPVVACFHFKRFEHSAK-QRRKITTYISFPLE-LDMTPFMASSKETRVNGQLQLPTNSANNENKYSLFAVVNHQGT-LESGHYTSFIRHHRDQWFKCDDAVITKASIKDVLDSEGYLLFYHKQVLEPEPEKVKEMTPQAY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZGB0-1", "uniprot_id": "D3ZGB0_RAT", "id": "D3ZGB0-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCKDYVYDIDIEQIAKE-EQGEALKLQASTSTEFSQQQCSVPSLGEKYPTWETTKPELELLGHNPRRRRIASSFTIGLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHR---------------CEMPSPELCLVCEMSSLFRELYSGNPSPHVPYK------------LLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHCKGDDVGKVASN-------------------PNHCNCIIDQIFTGGLQSDVTCQACHGVS-TTIDPCWDISLDLPGSCTSFWPMSPGRE-SSLNG-ESHIPGVTTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMKKLPVVACFHFKRFEHSAK-QRRKITTYISFPLE-LDMTPFMASSKETRMNGQLQLPTNSGNNENKYSLFAVVNHQGT-LESGHYTSFIRHHRDQWFKCDDAVITKASIKDVLDSEGYLLFYHKQVLEHEPEKVKEMTTQAY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NNY8-1", "uniprot_id": "UBP27_HUMAN", "id": "A6NNY8-1", "name": "Ubiquitin carboxyl-terminal hydrolase 27", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCKDYVYDKDIEQIAKE-EQGEALKLQASTSTEVSHQQCSVPGLGEKFPTWETTKPELELLGHNPRRRRITSSFTIGLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHR---------------CEMPSPELCLVCEMSSLFRELYSGNPSPHVPYK------------LLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHCKGDDVGKAANN-------------------PNHCNCIIDQIFTGGLQSDVTCQACHGVS-TTIDPCWDISLDLPGSCTSFWPMSPGRE-SSVNG-ESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFEHSAK-QRRKITTYISFPLE-LDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQGT-LESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFYHKQVLEHESEKVKEMNTQAY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VVR1-1", "uniprot_id": "NOT_DROME", "id": "Q9VVR1-1", "name": "Ubiquitin carboxyl-terminal hydrolase nonstop", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSETGCRHYQSY-VKEHSYDTFRVIDAYFAACVNRDARERKAIHCNCFECGSYGIQLYACLHCIYFGCR-GAHITSHLRSKKHNVALELSHGTLYCYACRDFIYDARSREYALINRKLEAKDLQKS----------------IGWVPWVPTTKETNLLLANARRRLVRPNQTIGLRGLLNLGATCFMNCIVQALVHTPLLSDYFMSDRHD---------------CGSKSSHKCLVCEVSRLFQEFYSGSRSPLSLHR------------LLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVKAKAEHESKSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVVCQACNGVS-TTYDPFWDISLDLG--------------ETTTHG--GVTP--KTLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHSAL-IDRKISSFIQFPVE-FDMTPFMSEKKN-------------AYGDFRFSLYAVVNHVGT-IDTGHYTAYVRHQKDTWVKCDDHVITMASLKQVLDSEGYLLFYHKNVLEYE------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50102-1", "uniprot_id": "UBP8_YEAST", "id": "P50102-1", "name": "Ubiquitin carboxyl-terminal hydrolase 8", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSICPHIQQVFQNEKSKDGVLKTCNAARYILNHSVPKEKFLNTMKCGTCHEINSGAT--FMCLQCGFCGCWNHSHFLSHSKQIGHIFGINSNNGLLFCFKCEDYIGNIDLINDAIL-------------------------------AKYWDDVCTKTMVPSMERRD--------GLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNN-------------CKVRSPDKCFSCALDKIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSYVLDLPNAKEVSRAN----------------NKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLSLDIKDK--------------------------KKLYECLDSFHKKEQLKDFN-YHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLNGSNRKLDDFIEFPTY-LNMKNYCSTKEKDKHSE------NGKVPDIIYELIGIVSHKGT-VNEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLKEQAYLLFYTIRQVN--------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q91W36-1", "uniprot_id": "UBP3_MOUSE", "id": "Q91W36-1", "name": "Ubiquitin carboxyl-terminal hydrolase 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSP--WVCLTCSSVHCGRYVNGHAKKHYEDAQIPLLNHKRSEKQEKAQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQK-VREHLQNLENS---------------AFTADRHRKRKLLENSSLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDSNVSLVEEFRKTLCALWQGSQTAFSPES------------LFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASN----KCCINGASTVVTAIFGGILQNEVNCLICGTES-RKFDPFLDLSLDIPSQFR------------SKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKALCLHLKRFHWTAY-LRNKVDTYVQFPLRGLDMKCYLLEPENS------------GPDSCLYDLAAVVVHHGSGVGSGHYTAYAVHEG-RWFHFNDSTVTVTDEETVGKAKAYILFYVERQARAGAEKL--------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:: : . ** *:* ****..*:* * . : . . . .: . . :: . : *: * :: ** ****:** :: :* .. :: :* * *:..: * * * . ** *:***: .* :** : *.* . * *:. *.: *:: :. ** . :::***. .*: ::.** ::*. : :: . :.* .:: * *: : *** :: *. :* :: : : :.*:*** . . ", "identical_positions": 66, "similar_positions": 90, "identity": "8.46%" }, { "cls_id": "homologset.agr.SGD:S000004837", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIM0-1", "uniprot_id": "MRE11_RAT", "id": "Q9JIM0-1", "name": "Double-strand break repair protein MRE11", "aln": "--MSPTDPLDDEDTFKILVATDIHLGFMEKDAVRGNDTFVTFDEILRLALENEVDFILLGGDLFHENKPSRKTLHSCLELLRKYCMGDRPVQFEIISDQSVNFGFSKFPWVNYRDGNLNISIPVFSIHGNHDDPTGADALCALDVLSCAGFVNHFGRSMSVEKVDISPVLLQKGSTKLALYGLGSIPDERLYRMFVNKKVTMLRPK-----------EDENSWFNLFVIHQNRSKHGSTNFIPEQFLDDFIDLVIWGHEHECKIGPTRNEQQLFYVSQPGSSVVTALSPGETVKKHVGLLRVK-GRKMNMQKLPLRTVRQFFMEDVVLANHPSLFNPDNPKVTQAIQSFCLEKIEEMLDSAERERLGNPQ-----QPEKPLIRLRVDYSG--------GFEPFNVLRFSQKFVDRVANPKDVIHFFRHREQKGKTG-EEINFGKLIIKPASEGTTL-RVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFVDKEEKDAIEELVKYQLEKTQRFLKERHIDALEDKIDEEVRRFRESRQRNTNEEDDEVREAMSRARALRSQSENAASAFSADDLS-FDITEQTADDSDDSQSAVPSRGRGRGRGRRGGRGQSTAPRGGSQRGR-DTGLGISTRGRSSKATASTSRNMSIIDAFRSTRQQPSRNVATKNYSETIEVDESD-DDDS-FPTSSRADQRWSGTAPSKRMSQSQTAKGVDFESDEDDDDDPFMSGSCPRRNRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61216-1", "uniprot_id": "MRE11_MOUSE", "id": "Q61216-1", "name": "Double-strand break repair protein MRE11", "aln": "--MSPTDPLDDEDTFKILVATDIHLGFMEKDAVRGNDTFVTFDEILRLALENEVDFILLGGDLFHENKPSRKTLHSCLELLRKYCMGDRPVQFEVISDQSVNFGFSKFPWVNYQDGNLNISIPVFSIHGNHDDPTGADALCALDVLSCAGFVNHFGRSMSVEKVDISPVLLQKGSTKLALYGLGSIPDERLYRMFVNKKVTMLRPK-----------EDENSWFNLFVIHQNRSKHGNTNFIPEQFLDDFIDLVIWGHEHECKIGPIKNEQQLFYVSQPGSSVVTSLSPGEAVKKHVGLLRIK-GRKMNMQKLPLRTVRRFFIEDVVLANHPNLFNPDNPKVTQAIQSFCLEKIEEMLDSAERERLGNPQ-----QPGKPLIRLRVDYSG--------GFEPFNVLRFSQKFVDRVANPKDVIHFFRHREQKGKTG-EEINFGMLITKPASEGATL-RVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFVDKEEKDAIEELVKYQLEKTQRFLKERHIDALEDKIDEEVRRFRESRQRNTNEEDDEVREAMSRARALRSQSETSTSAFSAEDLS-FDTSEQTANDSDDSLSAVPSRGRGRGRGRRGARGQSSAPRGGSQRGR-DTGLEITTRGRSSKATSSTSRNMSIIDAFRSTRQQPSRNVAPKNYSETIEVDDSD-EDDI-FPTNSRADQRWSGTTSSKRMSQSQTAKGVDFESDEDDDDDPFMSSSCPRRNRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49959-1", "uniprot_id": "MRE11_HUMAN", "id": "P49959-1", "name": "Double-strand break repair protein MRE11", "aln": "--MSTADALDDENTFKILVATDIHLGFMEKDAVRGNDTFVTLDEILRLAQENEVDFILLGGDLFHENKPSRKTLHTCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDGNLNISIPVFSIHGNHDDPTGADALCALDILSCAGFVNHFGRSMSVEKIDISPVLLQKGSTKIALYGLGSIPDERLYRMFVNKKVTMLRPK-----------EDENSWFNLFVIHQNRSKHGSTNFIPEQFLDDFIDLVIWGHEHECKIAPTKNEQQLFYISQPGSSVVTSLSPGEAVKKHVGLLRIK-GRKMNMHKIPLHTVRQFFMEDIVLANHPDIFNPDNPKVTQAIQSFCLEKIEEMLENAERERLGNSH-----QPEKPLVRLRVDYSG--------GFEPFSVLRFSQKFVDRVANPKDIIHFFRHREQKEKTG-EEINFGKLITKPS-EGTTL-RVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFVDKEEKDAIEELVKYQLEKTQRFLKERHIDALEDKIDEEVRRFRETRQKNTNEEDDEVREAMTRARALRSQSEESASAFSADDLMSIDLAEQMANDSDDSISAATNKGRGRGRGRRGGRGQNSASRGGSQRGRADTGLETSTRSRNSKTAVSASRNMSIIDAFKSTRQQPSRNVTTKNYSEVIEVDESDVEEDI-FPTTSKTDQRWSSTSSSKIMSQSQVSKGVDFESSEDDDDDPFMNTSSLRRNRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QPT3-1", "uniprot_id": "A0A8M9QPT3_DANRE", "id": "A0A8M9QPT3-1", "name": "Double-strand break repair protein", "aln": "-MASAGSTVDDEDTFKILIATDIHLGYLEKDAIRGNDTFVTFDEIMKQAMQNEVDFVLLGGDLFHDNKPSRKTMHSCMEVMRKYCMGDRPIIFEIISDQAVNFSHSRFPWVNYLDDNLNISIPIFSVHGNHDDPTGSDGLCAVDLLSCAGLVNHFGRSRSVEKVEISPVLLQKGDTRIALYGLGSIPDERLYRMFVNNQVTMLRPR-----------EDEDGWFNLFVIHQNRSKHGATNYIPEQFLDDFLDLVVWGHEHECKIAPVRNEQQLFYVTQPGSSVITSLSPGEAVKKHIGLLRVK-GKKMNLQKIPLQTVRQFFIQDVVLSDYPELFSPEQPNTMLKVQAFCQEKVEEMLEEAERERLGNPQ-----IPEKPLIRLRVDYSG--------GFEVFNTMRFSQKFVDKVANPKDILHFVRHRETKGNIKDEDVDFEALFSRPTSEVLQL-RVEDLVKEYFQTAEKNVQLSLLTEQGMGKAVQEFVDKEERDAIEELINYQLEKTQRYLRERRVDATEEKIDEEIRQFRDSK-RNTAEEDEEVQEAIIRAKAHRDRGETAR----DDDLGLSDDPADIAMESDEEPSSAPP-VRGRGRGSRGGRDPCASKRG---RAR-GAASRSGRGGRGRGSLSSPVKTKSIMDVFQDVSQRSTRGKTPKSYAEEITIEDSDSDEDVSFLKSSRTKQKLPSLSDSKRASQSQSLKGVCID--EDSGEDEFDPFKGSRKQRR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XYZ4-1", "uniprot_id": "Q9XYZ4_DROME", "id": "Q9XYZ4-1", "name": "Double-strand break repair protein", "aln": "MNGTTTAEQDADNVIRILVATDNHLGYGEKDAVRGEDSFTAFEEILELAVSEDVDMILLGGDLFHDAVPSQNALHKCIELLRRYTFGDRPVSLEILSDQGQCFHNAVNQSVNYEDPNLNIAIPVFSIHGNHDDPSGFGRLSSLDLLSTSGLVNYFGRWTDLTQVEISPVLMRKGESQLALYGLSHIHDGRLARLIKDFKVKFNCPENVANGEDGNESKEEEDWFHLLVVHQNRADRGPKNYLPEDLLPSFLHLVIWGHEHDCRIEPEENAKKRFYVSQPGSSVPTSLSEGEAKKKHVGLLEIY-KGKFKLKPLPLETVRPFVYESVVLADHADELGLVEGDASTKVFKFAQERVEAMIERAVAQHTGHPK-----QPTLPLIRLRLLYTD--------ESCMFNAIRFGEMLSTRVANVQDVVQFSKVVKR---TKTEAVNLDKEALRRALEADNATRVEELVDRYFEEAKSNKPLKLFHSKALAEMTYRLLEQRDADAAENIVKFYKEKAVDHLMEAMPN--DENIDEELERFRALHKHGDLLK-------MLDTQGLKVKKEEKS---------------MSVLGSEVNVSTAPATGRGAARGRGTARTR--------------AGATAATRGKGQ----------------LDVTVSSTR-------------------------TSGRQQTLLSSLMGSRNTASYVIS---------DDSD--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32829-1", "uniprot_id": "MRE11_YEAST", "id": "P32829-1", "name": "Double-strand break repair protein MRE11", "aln": "------MDYPDPDTIRILITTDNHVGYNENDPITGDDSWKTFHEVMMLAKNNNVDMVVQSGDLFHVNKPSKKSLYQVLKTLRLCCMGDKPCELELLSDPSQVFHYDEFTNVNYEDPNFNISIPVFGISGNHDDASGDSLLCPMDILHATGLINHFGKVIESDKIKVVPLLFQKGSTKLALYGLAAVRDERLFRTFKDGGVTFEVPT-----------MREGEWFNLMCVHQNHTGHTNTAFLPEQFLPDFLDMVIWGHEHECIPNLVHNPIKNFDVLQPGSSVATSLCEAEAQPKYVFILDIKYGEAPKMTPIPLETIRTFKMKSISLQDVPHLRPHDKDATSKYLIEQVEEMIRDANEETKQKLADDGEGDMVAELPKPLIRLRVDYSAPSNTQSPIDYQVENPRRFSNRFVGRVANGNNVVQFYKKRSPVTRSKKSGINGTSISDRDVEKLFSESGGELEVQTLVNDLLNKMQLSLLPEVGLNEAVKKFVDKDEKTALKEFISHEISNEVGILSTNEEFLRTDDAEEMKALIKQVKRANSVRPTPPKENDETNFAFNGNGLDSFR----------SSNREVRTGSPDITQSHVDNESRITHISQAESSKP--------------TSKPKRVRTATKKKIPAFSDSTVISDAENELGDNNDAQDDVDIDENDIIMVSTDEEDASYGLLNGRKTKTKTRPAASTKTASRRGKGRASRTPKTDILGSLLAKKRK------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.::**::** *:*: *:*.: *:*:: ::.*:: * .::**::: .***** **::::: :: :* :**:* :*::** . * *** * *:**:**:*.: *****.:* . *..:*:* :*::*:**: . ::.: *:*::**.:::*****. : * ** * : : *.: * * **:*: :***:: : . ::**::* .*:.:*:*****:* .* : * : ****** *:*. .*: *:: :* : :: :**.*:* * :.: * : . : . : * :. : : : .. . **:***: *: . **.: : :*** :::::* : . . :: : : * *. .: .: *.*: . .: : . .:::: : * ::::.. .: * :. :* :: : . : . .: * . * . . :. . ..: . * :. * ", "identical_positions": 128, "similar_positions": 193, "identity": "17.32%" }, { "cls_id": "homologset.agr.SGD:S000004839", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3U0B3-1", "uniprot_id": "DHR11_MOUSE", "id": "Q3U0B3-1", "name": "Dehydrogenase/reductase SDR family member 11", "aln": "----------------------------------------------------------------------MTRAGMERWRDRLALVTGASGGIGAAVARALVQQG---LKVVGCARTVGNIEELAAECKSAGYP--GTLIPYRCDLSNEEDILSMFSAVRSQHSGVDICINNAGMAR-PDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNIDDGHIININSMCGHRVPPQSVIHFYSATKYAVTALTEGLRQELLEAQTHIRATCISPGLVETQFAFKLHDKDPGEAAATYEHIKC-LRPEDVAEAVIYVLSTP-PHVQVGDIQMRPTEQVT--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V978-1", "uniprot_id": "G3V978_RAT", "id": "G3V978-1", "name": "Dehydrogenase/reductase SDR family member 11", "aln": "MWPSVEVPRAEPRPEAGPQGVGSRRSSNISKLPAPAPAVTRELPSFSNSRLNSAIPVPSSPNEVGRRLGTMTRAGMERWRDRLALVTGASGGIGAAVARALVQQG---LKVVGCARTVGNIEELAAECKSAGYP--GTLIPYRCDLSNEEDILSMFSAVRSQHSGVDICINNAGMAR-PDSLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININSMCGHRVPPQSVIHFYSATKYAVTALTEGLRQELLEAQTHIRATCISPGLVETQFAFKLYDKDPREAAATYEHIKC-LRPEDVAEAVIYVLSTP-PHVQVGDIQMRPTEQVT--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UWP2-1", "uniprot_id": "DHR11_HUMAN", "id": "Q6UWP2-1", "name": "Dehydrogenase/reductase SDR family member 11", "aln": "----------------------------------------------------------------------MARPGMERWRDRLALVTGASGGIGAAVARALVQQG---LKVVGCARTVGNIEELAAECKSAGYP--GTLIPYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLAR-PDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFAFKLHDKDPEKAAATYEQMKC-LKPEDVAEAVIYVLSTP-AHIQIGDIQMRPTEQVT--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q05016-1", "uniprot_id": "YM71_YEAST", "id": "Q05016-1", "name": "NADP-dependent 3-hydroxy acid dehydrogenase", "aln": "--------------------------------------------------------------------MSQGRKAAERLAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPN--AKVHVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIATEDIQDVFDTNVTALINITQAVLPIFQAKNSGD--IVNLGSIAGRDAYP--TGSIYCASKFAVGAFTDSLRKELIN--TKIRVILIAPGLVETEFSLVRYRGNEEQAKNVYKDTTP-LMADDVADLIVYATSRK-QNTVIADTLIFPTNQASPHHIFRG-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9Y140-1", "uniprot_id": "DHRS7_DROME", "id": "Q9Y140-1", "name": "Dehydrogenase/reductase SDR family protein 7-like", "aln": "----------------------------MKVQDMDKCAPSSDWNVLYWVLGTVLMPVALPLAIINIWQRFQAQKFRNQLPGKVVLITGASSGLGESLAHVFYRAG---CRVILAARRTQELERVKKDLLALDVDPAYPPTVLPLDLAELNSIPEFVTRVLAVYNQVDILINNGGISVRADVASTAVDVDLK-VMVVNYFGSVALTKALLPSMVKR--GSGHICFISSVQGKFAIP--QRAAYSASKHAMQAFADSLRAEVAN--KNINVSCVSPGYIRTQLSLNALTGSGSSYGKVDETTAKGMSPDKLAERILQCILRKEPDIIVSDVQAKIAYYLRHLCPSLYFWIMAKRAVKLENAEKKST", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: : .*:****.*:* : * . . ::: .** ::*.: *::: :.* :. : .. :** :**.* : .* . : :: .* . *: : : .. * :.*: *: . * *.*:*.*: *:::.** *: : .:*.. ::** :.*:::: . . . : : .:.:*: :: . :.* : ", "identical_positions": 39, "similar_positions": 88, "identity": "10.71%" }, { "cls_id": "homologset.agr.SGD:S000004840", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D3R9-1", "uniprot_id": "TAF7L_MOUSE", "id": "Q9D3R9-1", "name": "Transcription initiation factor TFIID subunit 7-like", "aln": "-MERGEEAPTEGAP---------------PEGALVEAKAPVIPEAPATDVSTTEEAGSKEPQVPSGPRPEGAGDTCDTRGARGP--PTPGRAKSQKTPRQGTARCQTLESAMRSMSVR-LECHDVEEQFILRLPPEQAYAVRKIIHSRNAAWKDKLKIDFSPDGHHAVVQVDNVSLPAKLVNLP-CVIGSLKTIDRKTFYKTADVSQMLVCS---------------------------PEGEPHSPPEEPVVSTG----PTVIGISEGKAERKKYNWKHGITPPLKNVRKKRFRKTTKKLPDVKQVDEINFSEYTQSPSVEKEVKRLLYSDAEAVSVRWEVVDDDDAKEIESQGSMP----------------------TTPGISQMGGASLSD--YDVFREMMGDSGSNSNDVEEKSN--EGDDDDDEDE----DDEDYGNEKEEEETDN------------SEEE------------------------------------------------------LEKELQAKFNEFS-LHEADQ-DYSSITMAIQKLIFIKEKRLQMIYKKAQRQKELLRKVENLTLKRHFQNVLGKLNIMEKEKCEQIYHLQEQLKCFLKE----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZWV0-1", "uniprot_id": "A0A8I5ZWV0_RAT", "id": "A0A8I5ZWV0-1", "name": "", "aln": "-MERGEEAPVEGAPTERAPAEGALAEAALPKAALAEAGAPDISEAPSTHAPTSEETGPKEPQVPISLGAESACDTSDTGGARGLVIPVPSRAEPHGT-RPSTARGRALQKAMRAMSLRHEESHEIEEQFILRLPPEQAYAVRKIIHSRNAATKDKLKIGFSPDGHHAVVQVENVSLPAKLVNLP-CVIGSLKTVDRKTFYQTADISQMLVCS---------------------------PEGEPHSSPEEPVISTG----PTVTGHIEGKAEKKKYNWKHGITPPLKNVRKKRFRKTTKKLPDVKQMDEINFSEYTQSPSVEKEVKRLLCSDAEAVSVRWEVVADDDTKEIESQGCIS----------------------TTSGTPQMGGAGSSE--YDVLREMMGETGSNSNDVEDKNSKIEDEDEDDQED----EDEDDGNEEKEEETDN------------SEEE------------------------------------------------------LEKELQAKFIQSS-LHEKEQ-DYTSIIMEIQKLIHIKEQKLQQIYKKAQRQKDLLRNVENLTLKRHFQNVLEKLNILEKEKCEQIYHLQEQLKCFLKE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1LV83-1", "uniprot_id": "F1LV83_RAT", "id": "F1LV83-1", "name": "", "aln": "-------------------------------------------------------MSKSQDELP----------------------------------------------------------HELENQFILRLPPEHASTVRKIIRSGNAAMRDKLKIDLSPDSRHAIVQVDDVSLSAKVVDLP-CVIGSLKTHDRKTFYKTADVSQMLLCS---------------------------AEGDLHSSPEEPATSAG----ATVMEN-EREAEEK-YIWKHGITPPLKNVRKKRFRKPTKKPPDMKQNGES-SSGYIDSKDVEKEVKRLLRSDAEAISCRWEIIVDDETKAVQSQTCTP----------------------HLPLPSEVGGHTSSA--CDMPQSTFSDSSSCKDDQENKEEEEEEEKEEDEEEGEAEEEEEEEEEEEEEEEDD------------SEED------------------------------------------------------LERELQAKFIEFS-LCEAKE-SSSSIILGIQKLIHSKERKLQEIQGKAQRQKDLLRKLENLTLKSHFQSVLEQLKLQEKQKAEQILFLQQQLKYFLKK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5H9L4-1", "uniprot_id": "TAF7L_HUMAN", "id": "Q5H9L4-1", "name": "Transcription initiation factor TFIID subunit 7-like", "aln": "-MECPEGQLPISSENDSTP-----TVSTSEVTSQQEPQILVDRGSETTYESSADIAGDEGTQIPADEDTQTDADSSAQAAAQAP---------------------ENFQEGKDMSESQDEVPDEVENQFILRLPLEHACTVRNLARSQSVKMKDKLKIDLLPDGRHAVVEVEDVPLAAKLVDLP-CVIESLRTLDKKTFYKTADISQMLVCT---------------------------ADGDIHLSPEEPAASTD----PNIVRKKERGREEK-CVWKHGITPPLKNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQGSIPGFL------------------ISSGMSSHKQGHTSSE--YDMLREMFSDSRSNNDDDE------DEDDEDEDED----EDEDEDEDKEEEEEDC------------SEEY------------------------------------------------------LERQLQAEFIESG-QYRANE-GTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDLIMKVENLTLKNHFQSVLEQLELQEKQKNEKLISLQEQLQRFLKK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R1C0-1", "uniprot_id": "TAF7_MOUSE", "id": "Q9R1C0-1", "name": "Transcription initiation factor TFIID subunit 7", "aln": "-------------------------------------------------------MSKNKDDAP----------------------------------------------------------HELESQFILRLPPEYAATVRRAVQSGHVNLKDKLSIELHPDGRHGIVRVDRVPLAAKLVDLP-CVTESLKTIDKKTFYKTADISQMLVAT---------------------------VDGDLYPPVEEAAATAD----PKANKKKDKDKEKK-FVWNHGITLPLKNVRKRRFRKTAKK-------------KYIESPDVEKEVKRLLSTDAEAVSTRWEIIAEDETKETENQGLDIS---------------------SPGMSGHRQGHDSLE--HDELREIFNDLSSSS------------EDE------------------EDVNILD------------TEED------------------------------------------------------LERQLQDKLNESDEQHQENE-GTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSSLQEELESLLEK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15545-1", "uniprot_id": "TAF7_HUMAN", "id": "Q15545-1", "name": "Transcription initiation factor TFIID subunit 7", "aln": "-------------------------------------------------------MSKSKDDAP----------------------------------------------------------HELESQFILRLPPEYASTVRRAVQSGHVNLKDRLTIELHPDGRHGIVRVDRVPLASKLVDLP-CVMESLKTIDKKTFYKTADICQMLVST---------------------------VDGDLYPPVEEPVASTD----PKASKKKDKDKEKK-FIWNHGITLPLKNVRKRRFRKTAKK-------------KYIESPDVEKEVKRLLSTDAEAVSTRWEIIAEDETKEAENQGLDIS---------------------SPGMSGHRQGHDSLE--HDELREIFNDLSSSS------------EDEDETQH----------QDEEDINIID------------TEED------------------------------------------------------LERQLQDKLNESDEQHQENE-GTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSSLQEELESLLEK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHY5-1", "uniprot_id": "TAF7_DROME", "id": "Q9VHY5-1", "name": "Transcription initiation factor TFIID subunit 7", "aln": "----------------------MPSLAVPHLTPISNEHLVSSKEVVFFWKNRIEMFEKKSDKVKQAEHKARD------------------------------------------------DGVELESQFIMRVPKELADTVHEAINAG--TIKDRLTIQLDPDLRYGEVRIDDQILYTKLVDLP-TVVESYKTIDNKSFYKSADICQILICK---------------------------EER------EDETEKES----PNKNKKKDPNKVDKKYLFPHGITPPCKNVRKRRFRKTLKK-------------KNVEAPEIEKEVKHLLRIDNEAVRVDYEIINEEDKPMDELEQSDIKPYNDADDDLQDESTMHASEKTIMEMSSQRHLQVESD--DDEASNFPSHRAPNMGVAVHDIFGEEVSSTDDEDEPDRGNNTMQRRVMEESSRLS------------ADDSRMSDFFGASGSNTGAGVVKMEQNVFSKSMFGHEASSPKLSAAGSSSNLAAPSGFYDSQMLAKREEFENMEFIDEPQPQYTQQQVQQKINQLTRQIRELKAQQVQKSTEIASIQNATLKQRMQETLDNLYTQVIERELELKDFENMLES--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05021-1", "uniprot_id": "TAF7_YEAST", "id": "Q05021-1", "name": "Transcription initiation factor TFIID subunit 7", "aln": "MAVIRIKKPRGPGEKDQPLEGEPKLKRIRIKTKVTDEDIKPKPKLKINLKKKKESADGKEKKNSLKLKLNLKKNEEPVKKIHKAP-------------KLRLKPIRIPGEAYDSEASDIEDDPLIESGVILRILPD--IQLEFVKNSLESGDYSGISIKWKNE-RHAVVTINDVMYGAILVDLP-TVIEVNKSVDRKNLLKTFDVSQMLLCIRPIQEEEEVYALEAPDTEDLVVKHFEGIEDEIWENKETFLKGYNGAPLSDMEAKHLKEIALKGYDYKHGISPPLYNVRNRRFRRKMDP---------------NEIDYVEKVVDMLLKQDKQAEEVSYDLVDKSELQARQERVSSWENFKEEPGEPLSRPALKKEEIHTIASAVGKQGAEEEG--EEGMEEEEEEDLDLGAAFESEEEGSGAEGDKEQQQEEVGDEVDQDTGGEDDDDDDDGDIEAAGGESESDDEKDENRQHTELLADELNELETTLAHTKHKLSKATNPLLKSRFIDSIKKLEKEAELKRKQLQQTEDSVQKQHQHRSDAETANNVEEEEEEEEEEEEEDEVDEDEEDDEENDEDEDNVHEREHIQENKVVRELDEAPAEETLDQNDLDMMMLFGAEGDE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "B0BN78-1", "uniprot_id": "B0BN78_RAT", "id": "B0BN78-1", "name": "Mitochondrial ornithine transporter 1", "aln": "-------------------------------------------------------MGAYR---------------------------------------------------------------DLASGDTLGSVEEHEIHPAIQAAIDLTAGAAGAAACVLTGQPFDTVKVKMQTFPYMYKGLADCFLKTYNQVGVHGLYRGTSPALLAYVA----------------------------QGSVLFLCYGFCQQFVR-----KVARVEQSAELN--DFETATAGSLASAFAALVLCPTEL---------------VKCRLQTMHEMRVAGKTKHSHNTIWSMVKSIFMKDGPLGFYRG---------------------LSTTLAQEIPGYFFYFGGYEISRSFFASGG-----------------------------------------------------------------------------------------------------------------SKDELGPVPLMLSGSFAGVCLWLIIFPVDCIKSRIQVLSMFGKPAGLIKTFINVVRNEGILALYSGLKATLIRAIPSNAALFVVYEYSRKMMMNVVEEY---", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : . * :. .*. . . . : : : . . : : : : . : . .. . . . : .: :.:: . : . :: : . :: : ", "identical_positions": 2, "similar_positions": 46, "identity": "0.32%" }, { "cls_id": "homologset.agr.SGD:S000004841", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2T7-1", "uniprot_id": "TFB2M_RAT", "id": "Q5U2T7-1", "name": "Dimethyladenosine transferase 2, mitochondrial", "aln": "MRGLAMRLPPRLALSVLAGRGPSCILGSGAATRKDWQERNRRSFSDLYTQPLPDCDFEESSSWTHKSRSEPTRHIACKKSARNLVRDLLEHQNPS-HQLILECNPGPGILTGALLKAG---ARVVAFESEKMFIPHLESLRKNADGELQVVHCDFFKIDPRYQELVR-PDVNSHTIFQNLGIKAVPWSAGVPIKVFGILPNKHERRLLWKILFDLYSCESIYRYGRVELNMFISEKEFRKLIATPKR--PDLYQVLGVLWQVACEIKFLHMEPWSSFS-VHAENGHLEKSKHSESLNLLKQNLYLVRMTPRRTLFTENLSPLNYDMFFHLVKHCFGKRN--------------APIIHHLR---SLSTVDPINILRQIRKRPGDTAAK-----------------MYPHDFKRLFETIERS---EDSVFKWIYDYCSDDSEL---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TL26-1", "uniprot_id": "TFB2M_MOUSE", "id": "Q3TL26-1", "name": "Dimethyladenosine transferase 2, mitochondrial", "aln": "MRGPAMRLPPRIALSALA-RGPSCILGSGAATRKDWQTRNRRGFSDFNIEPLPDSDLEESSPWTSRNRSEPTRHIACKKAARNLVRDLLEHQNPS-RQIILECNPGPGILTGALLKAG---ARVVAFESEKTFIPHLEPLQRNMDGELQVVHCDFFKMDPRYQEVVR-PDVSSQAIFQNLGIKAVPWSAGVPIKVFGILPYKHERRILWKILFDLYSCESIYRYGRVELNMFVSEKEFRKLIATPKR--PDLYQVMAVLWQVACDVKFLHMEPWSSFS-VHTENGHLEKSKHGESVNLLKQNLYLVRMTPRRTLFTENLSPLNYDIFFHLVKHCFGKRN--------------APIIRHLR---SLSTVDPINILRQIRKNPGDTAAR-----------------MYPHDFKKLFETIEQS---EDSVFKWIYDYCPEDMEF---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H5Q4-1", "uniprot_id": "TFB2M_HUMAN", "id": "Q9H5Q4-1", "name": "Dimethyladenosine transferase 2, mitochondrial", "aln": "MWIPVVGLPRRLRLSALAGAGRFCILGSEAATRKHLPARNHCGLSDSSPQLWPEPDFRNPPRKASKASLDFKRYVTDRRLAETLAQIYLGKPSRP-PHLLLECNPGPGILTQALLEAG---AKVVALESDKTFIPHLESLGKNLDGKLRVIHCDFFKLDPRSGGVIKPPAMSSRGLFKNLGIEAVPWTADIPLKVVGMFPSRGEKRALWKLAYDLYSCTSIYKFGRIEVNMFIGEKEFQKLMADPGN--PDLYHVLSVIWQLACEIKVLHMEPWSSFD-IYTRKGPLENPKRRELLDQLQQKLYLIQMIPRQNLFTKNLTPMNYNIFFHLLKHCFGRRS--------------ATVIDHLR---SLTPLDARDILMQIGKQEDEKVVN-----------------MHPQDFKTLFETIERS---KDCAYKWLYDETLEDR-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VH38-1", "uniprot_id": "TFB2M_DROME", "id": "Q9VH38-1", "name": "Dimethyladenosine transferase 2, mitochondrial", "aln": "---------------MLPLRCSWSFARANYSTKKELVTRYSGDFPEKLLN--------------RKQKVPTHMYIANSEAAARINQYLEPHFQSSGCDTVMELNSGAGYFTRHLLDRESQFRRIILLESMDHFMPKIQELHTLYPERVKVRQGDFVNLWKLVYMDKMDGGSRVADLLS--DVPQKAFTDDINMLVFGAVG---SYPFFKHLINSLIFQTSLFNLGRCEMILAMPPPIYIHLTCNNEIG-YLIYRSTSVLFQILFEHKFIAKVPREDFLPQQMAYSPTKSSKLGKVQSINPEYLYLVKFTPRRNLHELCQSQDLPALWFFIKQNYVSRRNRIIPNLEKWVPGCGPRLIINPKSSESVTPIYPDELPKKLPQYSCQSTTMSTRNYYPGINIYTQFGDLLPSQILTLFSQFRQWPEYGESSFLASLENALLKLETANDEPNLEDGVTLPEEDDAEADEIIEEESPVPATTPVKRRRKASS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14908-1", "uniprot_id": "MTF1_YEAST", "id": "P14908-1", "name": "Mitochondrial transcription factor 1", "aln": "--------------------MSVPIPGIKDISKLKFFYGFKYLWNP----------------------------TVYNKIFDKLD--LTKTYKHPEELKVLDLYPGVGIQSAIFYNKY--------CPRQYSLLEKRSSLYKFLNAKFEGSPLQILKRDPYDWSTYS--NLIDEERIFVPEVQSSDHINDKFLTVANVTG-EGSEGLIMQWLSCIGNKNWLYRFGKVKMLLWMPSTTARKLLARPGMHSRSKCSVVREAFTDTKLIAISDANELKGFDSQCIEEWDPILFSAAEIWPTKGKPIALVEMDPIDFDFDVDN-------WDYVTRHLMILKR--------------TPLNTVMD---SLGHGGQQYFNSRITDKDLLKKCP---------------IDLTNDEFIYLTKLFMEWPFKPDILMDFVDMYQTEHSG----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: . . . : . . ::: .* * : : . :: : . * ... ::.: : : . : * . . : : : ::. *: :: : : :* . : . ..* . : : : *:.: * . : .: :: . : . : *: : :: . . : :: * . : . : . ", "identical_positions": 11, "similar_positions": 81, "identity": "2.26%" }, { "cls_id": "homologset.agr.SGD:S000004842", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NS46-1", "uniprot_id": "RRP5_MOUSE", "id": "Q6NS46-1", "name": "Protein RRP5 homolog", "aln": "------------------------------MANLEESFPRGGTRKLHKSEKSSQQVVEQDNLFDVS-----TEEGPIKRKKS-QKGPAKTKKLKIEKRKSIKSIKEKFEILSLESLCEGMRILGCVKEVSELELVVSLPNGLQGFVQVTEVCDAYTQKLN-----------------------------EQVAQEEPLEDLLRLPELFSPGMLVRCVVSS-----LDVTESGKKSVKLSVNPKRVNKVLSADALRPGMLLTGTVSSLEDHGYLVDIGVGGTRAFLSLKKAQEYIRQKNKGAKFKVGQYLTCVVEEVKSNGGVVSLSVEHSEVSSAFATEEQSWNLNNLLPGLLVKAQVQKVTQFGLQLNFL-TFFKGLVDFMHLE--PKKMGSYSSNQTVKACILCVHPRTRVVRLSLRPIFLHPGRPLTRISYQQ-------LGAVLDDVPVQGFFKNAGAIFR--LKDGVLAYARVS-HLSDSKKAFN-AEAFKPGSTHKCRIIDYSQMDELALLSLRKSIIAAPFLRYHDIKIGTVVKG-TVLAIK-PFGILVKVG-EQIKGLVPSMHLADIMMKNPEKKYSPGDEVKCRVLLCDPEAKKLIMTLK--KTLVTSKLSLITCYEGAK----PGLQTHGVIIRVKDYGCIVKFYNDVQGLVPKHELSTQHIPDPETVFYTGQVVKVAVLSCEPSKERMLLSFRLLSDSRPKDPGVESSQKKTGAVRIG-QLVDVKVLEKTKTGLEVAILPHNTPAFLPTPHLSD-HAANGPLLHHWLQTGDTLHRVLCLSQSERH-ILLCRKPALVSTVEGGQDPKSLSEIQPG---MLLIGFVKCIKEYGVFVQFPSGLSGLSPKTIMSDKFVTTPSEHFVEGQTVVAKVTNVDESKQRMLLSLRLSDCSLGDSASTSFLLLCQCLEELQGIRSLMSNQ-DSVLIQTLADMTPGMVLDAVVHEVLEDGSVVFSSDPVPDLVLRASRYHRAGQEVEPGQKKKVVVLHVDMLKLEVHVSLHQDLVNRKTRKLRKSSRHQGIVQHLEESFAVASLVETGHLVAFSLISHLNDTFHFDSEKLRVGQGVCLTLKTTEPGVTGLILAVEGPASKRTRMPVQRDSETVDDKGEEKEEEEEEEEKEEENLTVKSKKRHSLAIGDKVTGTIKAVKATHVVVTLADGFVGCIHASRILDDVPVGTSPTTTLKAGKKVTARVIGGRDVKTSKFLPISHPRFVLTILELSVRPSELKGSYSALNTHSESPVEKIRQYQAGQTVTCFFKKYNVMKKWLEVDIGPDIRGRIPLLLTSLSFKVLKHPDKKFQVGQAIEATVVDPDVPR-AFLCLSLIGPYRLEEGEVAMGRVMKVVPNRGLTVSFPFGKIGKVSMFHLSDSYSEAPLEDFCPQKIVRCYILSTAHR-VLALSLRSSRTNRETKNRIEDPEINSIEDVKEGQLLRGYVKCVLPSSVIIGLGPSVLGLAKYSHVSECVPPEKELYNGCLPEGKLVTAKVLRVNPMKNLIELSLLPSDTGRPDVFSPAPEP---KQEERSGGAEE-GQK--------RKEKNQKRREE-------KEEPQKSQRGGRGKRERQESESEQELVNKRPKKSGAAEEDDSGVEVYYREGEDEVGEPKLPPRGKQTKSTEVPRLHLSSGFLWDVGLDSLTPALPLREESSDSE-DEQPHQAKKKKGKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKYKEAGELYNRMLKRFR-QEKAVWIKYGAFVLGRSQAGASHRVLQRALECLPAKEHVDVIVKFAQLEFQLGDVERAKAIFENTLSTYPKRTDVWSVYIDMTIKHGSQTAVRDIFERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAKALEYVEAKSSALED-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZNI3-1", "uniprot_id": "D3ZNI3_RAT", "id": "D3ZNI3-1", "name": "Protein RRP5 homolog", "aln": "------------------------------MANLEESFPRGGTRKPHKSEKSSQPVVEQDNLFDIS-----TEEGSVKRKKS-QKGPAKTKKLKIEKRKSNKSMKEKFEILSLESLCEGMRILGCVKEVNELELVVSLPNGLQGFVQVTEICDAYTQKLN-----------------------------EQVAQEEPLEDLLRLPELFSPGMLVRCVVSS-----LDVTESGKKSVKLSVNPKRVNKVLSAEALRPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLSLQKAQEYIRQKNKGAKFKVGQYLTCVVEELKSNGGVVSLSVEHSQVSSAFATEEQSWNLNNLLPGLVVRAQVQKVTQFGLQLNFL-TFFTGLVDFMHLE--PKKMGSYSSKQTVKACILCVHPRTRVVRLSLRPIFLHPGRPLTRISYQQ-------LGTVLDDASVEGFFEKAGAIFR--LRDGVLAYARLS-HLSDSKKAFS-AEAFKLGSTHRCRIIDYSQMDELALLSLRKSIIAAPFLRYQDIKTGTIVKG-KVLALK-PFGMLVKVG-EQMRGLVPSMHLADIMMKNPEKKFNTGDEVKCRVLLCDPEAKKLIMTLK--KTLVTSKLPAITCYEDAK----PGLQTHGVIIRVKDYGCLVKFYNDVQGLVPKHELSAQHIPDPERVFYTGQVVKVAVLNCEPSKERMLLSFKLLSGSEPKDESVKNSKKKGSTVNTGQQLVDVKVLEKTKNGLEVAILPHNIPAFLPTPHLSD-HVANGPLLHHWLQTGDTLHRVLCLSQSEKH-ILLCRKPALVSTVEGGQDPKSLSEIQPG---MLLIGFVKSIKDYGVFVQFPSGLSGLSPKTIMSDKFVTTPSEHFVEGQTVVAKVTNVDESKQRMLLSLRLSDCSLGDSASTSFLLLCQCLEELQGIRSLMSNQ-DSVLIQTLADMTPGMVLDAMVQEVLENGSVVFGGGPVPDLILRASRYHRAGQELEPGQKKKVVVLHVDALKLEVHVSLHQDLVNRKARKLRKNSRHQGIVQHLEESFAVASLVETGHLVAFSLISHLNDTFHFDSEKLRVGQGVCLTLKTTEPGVTGLILAVEGPASKRIRMPAQRDSETVDDKGEEEEEEEEED------LTVRSKKSHSLAIGDKVTGTIKSVKATHAVVTLDDGFIGCIHVSRILDDVPEGVSPTTTLKAGKKVTARVIGGRDVKTSKFLPISHPRFVLTILELSVRPSELKGDYRALNTHSVSPMEKIRQYQAGQTVTCFLKKYNVMKKWLEVDIEPDIRGRIPLLLTSLSFKVLKHPDKKFQIGQAIKATVVGPDIPR-AFLCLSLIGPYKLEEGDVAMGRVLKVLPNKGLTVSFPFGRIGKVSVFHLSDSYSEEPLTDFCPQKIVRCYILSTAHR-MLALSLRSSRTNKETKSKIEDPEVNSIEDIQAGQLLRGYVKSILPSSVVIGLGPSVMGLVKHSHVSQCVSREKELYDKCLPEGKLVTARVLCVNPKKNLIELSLLPSDTGKPDVFSASPEPPLPKQEGREGGTEK-GLKGESKRSQRRREKNQKMREESGLYSQEKKEPRKSQRGGQSKRERQESESEQELVNKRPKKSGAPEDDDSGVEVYYREGEDEVEEPKVPPGGKQSKPTEVPRLQLSKGFIWDVGLDSLTPALPLRGESSDSEEDEQPHQAKKKKGKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLAKVFERAVQYNEPLKVFLHLADIYTKSEKFKEAGELYNRMLKRFR-QEKAVWIKYGAFVLGRSQAGASHRVLQRALECLPTKEHVDVIVKFAQLEFQLGDVERAKAIFENTLTTYPKRTDVWSVYIDMTIKHGSQKEVRDIFERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAKALEYVEAKSSALEDQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14690-1", "uniprot_id": "RRP5_HUMAN", "id": "Q14690-1", "name": "Protein RRP5 homolog", "aln": "------------------------------MANLEESFPRGGTRKIHKPEKAFQQSVEQDNLFDIS-----TEEGSTKRKKS-QKGPAKTKKLKIEKRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGFVQVTEICDAYTKKLN-----------------------------EQVTQEQPLKDLLHLPELFSPGMLVRCVVSS-----LGITDRGKKSVKLSLNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNKGAKLKVGQYLNCIVEKVKGNGGVVSLSVGHSEVSTAIATEQQSWNLNNLLPGLVVKAQVQKVTPFGLTLNFL-TFFTGVVDFMHLD--PKKAGTYFSNQAVRACILCVHPRTRVVHLSLRPIFLQPGRPLTRLSCQN-------LGAVLDDVPVQGFFKKAGATFR--LKDGVLAYARLS-HLSDSKNVFN-PEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDIEPGAVVKG-TVLTIK-SYGMLVKVG-EQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLK--KTLIESKLPVITCYADAK----PGLQTHGFIIRVKDYGCIVKFYNNVQGLVPKHELSTEYIPDPERVFYTGQVVKVVVLNCEPSKERMLLSFKLSSDPEPKKEPAGHSQKKGKAINIG-QLVDVKVLEKTKDGLEVAVLPHNIRAFLPTSHLSD-HVANGPLLHHWLQAGDILHRVLCLSQSEGR-VLLCRKPALVSTVEGGQDPKNFSEIHPG---MLLIGFVKSIKDYGVFIQFPSGLSGLAPKAIMSDKFVTSTSDHFVEGQTVAAKVTNVDEEKQRMLLSLRLSDCGLGDLAITSLLLLNQCLEELQGVRSLMSNR-DSVLIQTLAEMTPGMFLDLVVQEVLEDGSVVFSGGPVPDLVLKASRYHRAGQEVESGQKKKVVILNVDLLKLEVHVSLHQDLVNRKARKLRKGSEHQAIVQHLEKSFAIASLVETGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVTGLLLAVEGPAAKRTMRPTQKDSETVD------EDEEVDP-----ALTVGTIKKHTLSIGDMVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGTSPTTKLKVGKTVTARVIGGRDMKTFKYLPISHPRFVRTIPELSVRPSELEDGHTALNTHSVSPMEKIKQYQAGQTVTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDKKFRVGQALRATVVGPDSSK-TLLCLSLTGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSIFHMSDSYSETPLEDFVPQKVVRCYILSTADN-VLTLSLRSSRTNPETKSKVEDPEINSIQDIKEGQLLRGYVGSIQPHGVFFRLGPSVVGLARYSHVSQHSPSKKALYNKHLPEGKLLTARVLRLNHQKNLVELSFLPGDTGKPDVLSASLEGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFR-QEKAVWIKYGAFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTDVWSVYIDMTIKHGSQKDVRDIFERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAKALEYVEAKSSVLED-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NCQ8-1", "uniprot_id": "A0A8M1NCQ8_DANRE", "id": "A0A8M1NCQ8-1", "name": "Protein RRP5 homolog", "aln": "------------------------------MASMEEDFPRGGTERKKPTDLIPH---EVDNLFDTP-----AKVVKKKKKSVKQDEAPKSKKQKVDEENIKLNTTTTVQILHLRDLTVGTLMLGCVKEVSDFEVVVGLPSGLVGYLPICNICDAYTNILN-----------------------------DKLDTDDGLEEVVPLSKLFTPGMLIRCVVSS-----LDSAKEGHISLKLSINPKDVNKALNSVALKPAMTLSGCVESVEDHGYLVDIGIGGTKAFLPKK-------STSSKQDLYVGQYVLVLIEDVKDSGRVVRLSQNPQALVKACAETKQGWTLDNLLPGLLIHGCVKRVTPHGLIVTFL-SSFTGVVDFLHLD--EDKESTYSKGQEILARILYVQPSTRQVGLSLRSHLLPPGGAVLDLHFSER------VGEVVQGCQMTSLHHYSGALMK--MLDGSRAFVHRN-LLKEPKEELD-TNHLMSQTQHILRIINYSPIEQIYQATLRWSSIETPFFSCQDIKVGQIVEG-TVTDLQ-KHGVYVRIG-EHIRGMIPRIHLADVTLKNPEKKFYPGLKVKCRVLSVEAQKKLLILTRK--KALVESTLPIFQSYSDAR----PGRISHGFVVCIKEFGCIVRFYEDVKGLVPMQELTTETVTNPEELFFVGQVVKVKVLKCDEEKKMLRLSFKSVTEEDVREE-----QIAKFDFIVG-KMVDARVCRKVLNGLEVSIIPEEVQAFLPTTHLSD-HVTNCLPLWMALEEGDTICNLMCLTNYKKKGIVLTKKPHLKAYIEDGAVPKNFSELQVG---MQMVGWVKNIMPYGVFISFPYGVFGLAPIANMGDQFIKETSGIFDIDQTVVAKVTNLDEEKQGFLVSLKLSELSLSENEFHTRLIQG--LKERRNISEMRAGRGDSDVLWKLSALTVGDQMKMIVGDTTEDGSVMLTSDQLSGVTVLASKYHKEGVNLTPGCKLNAVILHIDFVKSQVHVSLRPKLNIKKE-ELEKDARFTAKVQFADKDFAVVSLATTSDLTFFPTRPHLNS--IFDSKKFSVGS--CLDVKVDDP-------NCEDLAGFPLISYQSSN------------------------AKHEQHKPNEERLGELMKVTVKKLKALCVLVNLPSGNTGRVHVSQILEFPDIGSCPTSVLKVGMEMEARVIGGRAVRAHNFLAISHPDYNISIPELSFLESKLK---------VSDMVNKLEKYKPGDDIICFPSKYIKKEQLLEVHVKPDIMGAVPLLAMCNKLGLSKHPQRLFKPGQALSAKVVSVDPKKPIQFSLSLTGTHKLEPGMNTLAMVQKIQPHKGLMLALPYENTGLAHLTDLSDSYTEKPLESYKEGQIIRCHVIEQKIK-EFNVSLRPSRLNKDKHDIVEDPEIQSIADIKEGQSIRGYVSSVNDQGIFLRLSRTITGRVLFQNATKYYMNDPKVLIKHVGQNALVAAKVLSVDSENLHVNLSLLSKDTGKPDLLPESLELPLRLTGEEK---EKHDKKAAVKRKRTLSESQQQDNEN------TEQKTKRIKVDEECRLVEEPREQKETLKEKKKKKKSKKEDSDSGVEVFFRETDETVSDKKSGKVKVKCKEQEPNRLQVTSSFPWESTLGSLTPFAPADDNQNSSEDEEEVKSKPAKKSRKELKQEQQNTEQKPSKLEAELMDTSVRPDNSTAFERLLLSSPDSSLLWLQYMAFHLQATQIEQARAVAERALKTISFREEQEKLNIWVAMLNLENMYGTPDSLQKVFERAIQYCEPLLVYQQLADIYAKSEKIKEAESLYKSMVKRFR-QDKAVYLSYGTFLLRQRQSDAANALLQRALQSLSSKEHVDLIARFARLEFQFGNSEKAKSMFDKVLTTYPKRTDLWSVFIDLMVKHGSQKEVRELFDRVIHLSVSVKKIKFFFKRYLEYEKKNGTPETIQVVKQKALEYVESKGAEATS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05022-1", "uniprot_id": "RRP5_YEAST", "id": "Q05022-1", "name": "rRNA biogenesis protein RRP5", "aln": "MVASTKRKRDEDFPLSREDSTKQPSTSSLVRNTEEVSFPRGGASALTPLELKQVANEAASDVLFGNESVKASEPASRPLKKKKTTKKSTSKDSEASSANSDEARAGLIEHVNFKTLKNGSSLLGQISAITKQDLCITFTDGISGYVNLTHISEEFTSILEDLDEDMDSDTDAADEKKSKVEDAEYESSDDEDEKLDKSNELPNLRRYFHIGQWLRCSVIKNTSLEPSTKKSKKKRIELTIEPSSVN-IYADEDLVKSTSIQCAVKSIEDHGATLDVGLPGFTGFIAKK-------DFGNFEKLLPGAVFLGNITKKSDRSIVVNT-----DFSDKKNKITQISSIDAIIPGQIVDLLCESITKNGIAGKVF-GLVSGVVNVSHLR--TFSEEDLKHKFVIGSSIRCRIIACLENKSGDKVLILSNLPHILKLEDALR------STEGLDAFPIG--YTFESCSIK--GRDSEYLYLALD-DDRLGKVHSSRVGEIENSENLSSRVLGYSPVDDIYQLSTDPKYLKLKYLRTNDIPIGELLPSCEITSVS-SSGIELKIFNGQFKASVPPLHISDTRLVYPERKFKIGSKVKGRVISVNSRGNVHVTLKKSLVNIEDNELPLVSTYENAKNIKEKNEKTLATIQVFKPNGCIISFFGGLSGFLPNSEISEVFVKRPEEHLRLGQTVIVKLLDVDADRRRIIATCKVSNEQAAQQK------DTIENIVPGRTIITVHVIEKTKDSVIVEIPDVGLRGVIYVGHLSDSRIEQNRAQLKKLRIGTELTGLVIDKDTRTRVFNMSLKSSLIKDAKKETLPLTYDDVKDLNKDVPMHAYIKSISDKGLFVAFNGKFIGLVLPSYAVDSRDIDISKAFYINQSVTVYLLRTDDKNQKFLLSLKAPKVKE----------------EKKKVESNIEDP-VDSSIKSWDDLSIGSIVKAKIKSVKKNQLNVILAANLHGRVDIAEVFDTYEEITDK----------------------KQPLSNYKKDDVIKVKIIGNHDVKSHKFLPITHKISKASVLELSMKPSELKS-----------------------------------------------------------------------KEVHTKSLEEINIGQELTGFVNNSSGNHLWLTISPVLKARISLLDLADNDSNFSENIESVFPLGSALQVKVASIDREHGFVNAIGKSHVDINMSTIKVGDELPG--------RVLKIAEKYVLLDLGNKVTGISFITDALN-DFSLTLKEAFEDKINNVIPTTVLSVDEQNKKIELSLRPATAKTR------------SIKSHEDLKQGEIVDGIVKNVN-DKGIFVYLSRKVEAFVPVSKLSDSYLKEWKKFYKPMQYVLGKVVTCDEDSRISLTLRESEINGDLK------VLKTYSDIKAGDVFEGTIKSVTDFGVFVKLDNTVN-VTGLAHITEIADKKPEDLSALFGVGDRVKAIVLKTNPEKKQISLSLKASHFSKEAELAS-------------------------------------------------------TTTTTTTVDQLEKEDEDEVMADAGFNDSDSESD-------IGDQNTEVADRK--------PETSSDGLSLSAGFDWTA---SILDQAQEEEESDQDQEDFTENKKHKHKRRKENVVQDKTIDIN-----------TRAPESVADFERLLIGNPNSSVVWMNYMAFQLQLSEIEKARELAERALKTINFREEAEKLNIWIAMLNLENTFGTEETLEEVFSRACQYMDSYTIHTKLLGIYEISEKFDKAAELFKATAKKFGGEKVSIWVSWGDFLISHNEEQEARTILGNALKALPKRNHIEVVRKFAQLEFAKGDPERGRSLFEGLVADAPKRIDLWNVYVDQEVKAKDKKKVEDLFERIITKKITRKQAKFFFNKWLQFEESEGDEKTIEYVKAKATEYVASHESQKADE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VC94-1", "uniprot_id": "RRP5_DROME", "id": "Q9VC94-1", "name": "rRNA biogenesis protein RRP5", "aln": "------------------------------MVPNEKSFPRGGTIHS----EVKTDDVSLNIVFGAS-----------QKKVKKAPKVKENLLSYETEEQNGQLEAFSAETLNMDTLQEDMLVMGVVKELTATALQIALPGRMFARTLVADISDAYTRVAK-------------------------------AAMSGDTSEYHDLTELFQLGRIVYGKAIK-----TEKLDTGRVSLLLSLKPADVHGNLHHKSIKKGFIFSGAVAEALEHGYVIESGVQGLQAFVPCEK---------PAQKLHVGQLAFLKVKTVHHDTHQSTCTCVQVEQDQLRIKSQNETNLDYILPGSIVKFKVAKHLKDGLKGSIMNESFSAYVNEHHLANALDTLDAYELNEDYNARVLYVMPLTKLVYLTLNLDIKTGAAVAKDQDEEEQEVEPIKVGSVVEKAKVLRLGSGGVVLLLNKKLKGIISYGSIRGNFKGNYDKDEVLSKYGRKTKHKVRILGYDVIESLYYCSDDPNVVNEKLFCLEDINAGDLVTAKIFKKDDKIKGWSVRIG--KVNGILEQFYLA------PNVRYDVGQSLKCRVLEVNAERKICYVSNR--AEYLGKGIKILTDYASAH----VGNVYMGTVVRCEDTYVLVKFGNGIKGVLHRQNLKENSS------FFEGQTTKFRILTRNKDQITLTLPEDK--------------------FQLG-EICPVEITNALDAGLEVKIT------FAAEDDEEDEDGNPKLEEFVGLIPLRLLSDHLELLHAQMR--------------------------------------VHPAGSYTDAACIMQNIFSLRDVPYFSG-QLTKDWQSVQVGDIIRSYVKHATDQVVDLMVCVRN------------------------------------------YNKPVKVHVKMLRLNAVKNAPVELVPEQLLWVKVLSKEVETK------------------------------TLTVSAKLTDVWSGDLSDTAKLVEGYLNEVAQIKAG-------------------------------------------------------------------------------------LEEASAPISKYSVGEKINVVFKGIDATTNDWVYTVEGNGKVSALLLSSLVG-------------TAKAPEMGSKHEAVILWIEYSSDVLLISNKKLDIAHISPS-----------GELSTNLIGKAG-------MKAKVLLKLESVAVCSLKKGTNPLVICPIRLHPNDIEN----------------------------SGSAELRQGDFCN----------IAFIHDKLHIAVPETVWRLWRGVKRTAGTEVAPVKAKKAKVEESPKQ----------------------------------------------------KKTTIEETSAQKKVKAKAKVETKTEAKAIPTKRKAEVVEKITNGQKKTQPLTNGIVKE---------------------------------------------------------------KPKQNGKLFFEDKTPAKNAKSETPKSNG----------------------------------AEGKSRLPGVSSFWEDDVNQSKEGSSDEDEELNVAETQKNAAKKKRLSAKEKAKAEIKEEQRLREIEERNADPKARLETIDQYERLVIAQPNNSISWLKYIAFLLSNTEIEKARALARRAISTISFRETQELRNMWSALLNMELVYSN--NFDDVLKEALNCNDPLEIYISVVDILKKNKRKDRLSSVLTTVLNKFK-TELRVWPVAAEAYFWLGKSDQVHNLLQRALRALPNQEHIPCIVSFAKLYAKHDNNDMAQTLLDDVVTSYPKRIDIWSVYVDMLIKAGLIDSARNVLERAVVQKLKPNKMQVIYKKYLQLEENHGTDATVAKVKQQAEQWVKNYAKTVK--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .*****: . :: * . . : : : . * . ::* :. :. : : :.. : . : .:.: :* : .: * . * * : . . . : : *:::* *: : . : * . :** :: *: * .*:. .: * : : .:: ::** :: *: ..: ... *: ** . : : . : :: : : .. : . *::.*. ::.: : . : : .** * :: . . . * ::: :... : :::: *: :: * .:* **: :.. : : . : . * .*: . . : : :: * .:.*.: ::. : **.. . :* : .: : . . * : ..: . .: * : . . .* * : : . . : :: : . .* . . . .: : : . :. :::.:: . :. .. :: : : :. . * . : . . :*: :. .: . . : : . :.. . . :.. .. . * .: : . : : . . . *. * : : : . . : : :: : . . . . : : *: . . . . . . . * . :. . : ** . . : . :. ::**::..*:.*: *::*:** *. ::**:** :*.**:.**.*** * *:* *:**:* :.. .: .*:..* : :. :. : .* .:: .. .: . ::* . :: . : : . :* .**..*. ::*: : **:* .: : .::::: :: *** *:*.*::* :* ..::::* : .: :: :.:::::*: *:..* : ** :* ::* ", "identical_positions": 117, "similar_positions": 388, "identity": "5.89%" }, { "cls_id": "homologset.agr.SGD:S000004843", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63326-1", "uniprot_id": "RS10_RAT", "id": "P63326-1", "name": "Small ribosomal subunit protein eS10", "aln": "MLMPKKNRIAIYELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQSLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLHLP-----------PEIVPATLRR-SRPETGRPRPK-GPEGERPARFTRGEADRDTYRRSAVPPGADKKAEAGAGSATEFQFRGGFGRGRGQPPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63325-1", "uniprot_id": "RS10_MOUSE", "id": "P63325-1", "name": "Small ribosomal subunit protein eS10", "aln": "MLMPKKNRIAIYELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQSLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLHLP-----------PEIVPATLRR-SRPETGRPRPK-GPEGERPARFTRGEADRDTYRRSAVPPGADKKAEAGAGSATEFQFRGGFGRGRGQPPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46783-1", "uniprot_id": "RS10_HUMAN", "id": "P46783-1", "name": "Small ribosomal subunit protein eS10", "aln": "MLMPKKNRIAIYELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQSLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLHLP-----------PEIVPATLRR-SRPETGRPRPK-GLEGERPARLTRGEADRDTYRRSAVPPGADKKAEAGAGSATEFQFRGGFGRGRGQPPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NQ39-1", "uniprot_id": "RS10L_HUMAN", "id": "Q9NQ39-1", "name": "Putative ribosomal protein eS10-like", "aln": "MLMPKKNRIAIHELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQSLKSRGCVKEQFAWRHFYWYLTNEGSQYLRDYLHLPPEIVPATLHLPPEIVPATLHR-SRPETGRPRPK-GLEGKRPARLTRREADRDTYRRCSVPPGADKKAEAGAGSATEFQFRGRCGRGRGQPPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A5N7-1", "uniprot_id": "D4A5N7_RAT", "id": "D4A5N7-1", "name": "Small ribosomal subunit protein eS10", "aln": "MLMPKKNQIAIYELLFKEGVMDAQKDIHVPKHPELADKNVPNLHVTKAMQSLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLYLP-----------PEIVPATLSR-SRPETGRPRPK-GAEGERPARFTRGETD--TYRGELCPPGADKKAEAGAGSATEFLFREGFGHRCGQPPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VB14-1", "uniprot_id": "RS10A_DROME", "id": "Q9VB14-1", "name": "Small ribosomal subunit protein eS10A", "aln": "MFIPKANRVAIYEYLFKEGVLVAKKDSPIQKHSELDK--IPNLQVIKVMQSLNSRGWVKEQFAWRHFYWLLTNEGIEELRRYLHLP-----------PEIVPSTLTQTTRSNAVRPRGGPGGPGGGFGGASKTDDDRSNYRRGPGAYGMDKKGDVGAGTG-RVEYRGGFGRASRYDN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWG3-1", "uniprot_id": "RS10B_DROME", "id": "Q9VWG3-1", "name": "Small ribosomal subunit protein eS10B", "aln": "MFMPKAHRVAIYEYLFKEGVIVAKKDFHAQKHPELES--IPNLHVIKAMQSLHSRGLVKEQFAWRHYYWYLTNEGIEELRSYLHLP-----------PEIVPSTLKRPARSETVRPRPAVGGPRG-PGDASKTGEDRSAYRRAPGGSGVDKKGDVGPGAG-EVEFRGGFGRGSRN---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46784-1", "uniprot_id": "RS10B_YEAST", "id": "P46784-1", "name": "Small ribosomal subunit protein eS10B", "aln": "MLMPKQERNKIHQYLFQEGVVVAKKDFNQAKHEEIDT---KNLYVIKALQSLTSKGYVKTQFSWQYYYYTLTEEGVEYLREYLNLP-----------EHIVPGTYIQ-ERNPSQRPQRR--------------------Y--------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::** .: *:: **:***: *:** ** *: ** * *.:*** *:* ** **:*:::*: **:** : ** ** ** .***.* : * : **: * ", "identical_positions": 48, "similar_positions": 25, "identity": "26.97%" }, { "cls_id": "homologset.agr.SGD:S000004844", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTB4-1", "uniprot_id": "D3ZTB4_RAT", "id": "D3ZTB4-1", "name": "Vacuolar protein sorting-associated protein 11 homolog", "aln": "-MAAYLQWRRFVFFEKELVKEPLGNDGATPGAAPTSGPTASKFLCLPPGITVCDSGRGSLVFGDMEGQIWFLPRSLQLTGFQAYKLRVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEKRDGGNPLCTRILPAI-PGTEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQILHKGSYPVTGLAFRQAGK----TTHLFVVTTENVQSYIVSGKDYPR---VELDTHG----CGLRCSALSDPSQDLQFIVAGDECVYLYQPDERGPCFAFEG--HKLIAHWFRGYLVIVSRDRKVSPKSEFTSRDSQNSDKQILNIYDLCNKFIAYSAVFEDVVDVLAEWGS----LYVLTRDGRVHALQEKDTQTKLEMLFKKNLFEMAINLAKSQHLDSD-GLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEPSYVIRKF-----LDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKTKSESEVH---------------------FDVETAIKVLRQAGYYSHALYLAENHAHH----EWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQLLKGLCT-DYRPS--------------------------------LEGRGDREFPS----CRANSEE----------FIPIFANNPRELKAFLEHMSEVQPDSP------QGIYDTLLELRLQNWAHEKDPQAKEKLHAEAISLLKSGR----------FCDVFDKALVLCQMHDFQDG----------VLYLYEQGKLFQQIMHYHMQ--HEQYRQVIAVCERHGEQEPSLWEQALSYFARKEEDCKEY------VAAVLRHIENKSLMPPLLVVQTLAHNSTATLSIIRDYLVQKLQKQSQQIAQDELRVRRYR----EETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESD------ADCPTCLPENRKVMDMIRAQEQKRDLHDQFQHQLKCSN---DSFSVIADYFGRGVFNKLTLLTDPPTARLTP-SLEAGLQRDLLMHSRRGT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91W86-1", "uniprot_id": "VPS11_MOUSE", "id": "Q91W86-1", "name": "Vacuolar protein sorting-associated protein 11 homolog", "aln": "-MAAYLQWRRFVFFEKELVKEPLGNDGAAPGAAPVSGSAASKFLCLPPGITVCDSGRGSLVFGDMEGQIWFLPRSLQLTGFQAYKLRVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEKRDGGNPLCTRIFPAI-PGTEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQILHKGNYPVTGLAFRQAGK----TTHLFVVTTENVQSYIVSGKDYPR---VELDTHG----CGLRCSALSDPSQDLQFIVAGDECVYLYQPDERGPCFAFEG--HKLIVHWFRGYLVIVSRDRKVSPKSEFTSRDSQNSDKQILNIYDLCNKFIAYSAGFEDIVDVLAEWGS----LYVLTRDGRVHALQEKDTQTKLEMLFKKNLFEMAINLAKSQHLDSD-GLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEPSYVIRKF-----LDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKTKSESEVH---------------------FDVETAIKVLRQAGYYSHALYLAENHAHH----EWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKTLMHHIPEQTTQLLKGLCT-DYRPS--------------------------------LEGRGDREALS----CRASSEE----------FIPIFANNPRELKAFLEHMSEVQPDSP------QGIYDTLLELRLQNWAHEKDPQAKEKLHAEAISLLKSGR----------FCDVFDKALVLCQMHDFQDG----------VLYLYEQGKLFQQIMHYHMQ--HEQYRQVIAVCERHGEQEPSLWEQALSYFARKEEDCKEY------VAAVLRHIENKSLMPPLLVVQTLAHNSTATLSIIRDYLVQKLQKQSQQIAQDELRVRRYR----EETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESD------ADCPTCLPENRKVMDMIRAQEQKRDLHDQFQHQLKCSN---DSFSVIADYFGRGVFNKLTLLTDPPTARLTP-SLEAGLQRDLLMHSRRGT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H270-1", "uniprot_id": "VPS11_HUMAN", "id": "Q9H270-1", "name": "Vacuolar protein sorting-associated protein 11 homolog", "aln": "-MAAYLQWRRFVFFDKELVKEPLSNDGAAPGATPASGSAASKFLCLPPGITVCDSGRGSLVFGDMEGQIWFLPRSLQLTGFQAYKLRVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEKRDGGNPLCTRIFPAI-PGTEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQILHKGNYPVTGLAFRQAGK----TTHLFVVTTENVQSYIVSGKDYPR---VELDTHG----CGLRCSALSDPSQDLQFIVAGDECVYLYQPDERGPCFAFEG--HKLIAHWFRGYLIIVSRDRKVSPKSEFTSRDSQSSDKQILNIYDLCNKFIAYSTVFEDVVDVLAEWGS----LYVLTRDGRVHALQEKDTQTKLEMLFKKNLFEMAINLAKSQHLDSD-GLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEPSYVIRKF-----LDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSESEVH---------------------FDVETAIKVLRQAGYYSHALYLAENHAHH----EWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQLLKGLCT-DYRPS--------------------------------LEGRSDREAPG----CRANSEE----------FIPIFANNPRELKAFLEHMSEVQPDSP------QGIYDTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGR----------FCDVFDKALVLCQMHDFQDG----------VLYLYEQGKLFQQIMHYHMQ--HEQYRQVISVCERHGEQDPSLWEQALSYFARKEEDCKEY------VAAVLKHIENKNLMPPLLVVQTLAHNSTATLSVIRDYLVQKLQKQSQQIAQDELRVRRYR----EETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESD------ADCPTCLPENRKVMDMIRAQEQKRDLHDQFQHQLKCSN---DSFSVIADYFGRGVFNKLTLLTDPPTARLTS-SLEAGLQRDLLMHSRRGT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TWK3-1", "uniprot_id": "A0AB32TWK3_DANRE", "id": "A0AB32TWK3-1", "name": "Vacuolar protein sorting-associated protein 11 homolog", "aln": "-MAAFLQWRRFVFFDKETVKDPSEN---------------GKNFQLPMGISACDSGRGHIVLGDMDGQIWFLTRSLQLSSFQAYKLRVTHLYQLKQHNILVSVGQDEPGINPLVKVWNLDKRDSGSPLCTRIFPAI-PGNKPTEVSCLSVHENLNFMAIGFTDGSVVLTKGDITRDRHSKTLSLHEGNCPITGLAFRQAGK----ITHLFVATLEKVQCYTLSVKEYPR---VELDTHG----CALRCSALTDPSQDSQFIVAGDDCVYLYQPDERGPCFAFDG--HKLLTHWHRGYLLLLTHSNKSPSKSDYGSRQTSPTEKHILTIYDLDNKFIAYSAVFDDVIDVLAEWGS----FYVLTSDRTVYMLQEKDTQTKLEMLFKKNLFVMAINLAKSQHLDND-GLSEIFRQYGDHLYVKGDHDGAIQQYIRTIGKLEPSYVIRKF-----LDAQRIHNLTAYLQALHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKS-NESEVH---------------------FDVEIAIKVLRQAGYHSHAVFLAERHMHH----EWYLKIQLEDLKNYQEALRYIGRLPFDQAESNMKRYGKTLMHHVPESSTILLKRLCT-DYHPS--------------------------------KDS-TDRDSLDRPVENKANPEE----------FIPVFANNPRELRLFLEHMIEVDPFSP------EGVYDTLLELRLQDWAHEQDPGKKKVLQEAALSLLRSD------------NTVFDKALVLCQMHNFKEG----------VLYLYEKGKLYQQIMHYHMQ--NEEYGKVVEACKRYGDSEVCLWEQALGYFARKEENCKSY------ISEVLKHIDDNNLMPPLLVVQTLAHNSTASLSVIKDYLINKLERETQQIEEDERKIRQYR----EETAHLRSEIQELKTCAKIFQKTKCSMCNSPLELPSVHFLCGHSFHQHCLESFAESE------AECPTCTPENRKVMDMLRAQDQKRDLHDHFHRQLRCSN---DGFSVIADYFGRGVFNKLTLITDPPGGKGGAGNLEAEFNRDLLINTKRNV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P12868-1", "uniprot_id": "PEP5_YEAST", "id": "P12868-1", "name": "E3 ubiquitin-protein ligase PEP5", "aln": "--MSLSSWRQFQLFENIPIRDPNFG-----------GDSLLYSDPTLCAATIVDPQTLIIAVNSNIIKVVKLNQSQVIHEFQSFPHDFQITFLKVINGEFLVALAESIGKPSLIRVYKLEKLPNREQLYHSQVELK-NGNNTYPISVVSISNDLSCIVVGFINGKIILIRGDISRDRGSQQRIIYEDPSKEPITALFLNND----ATACFAATTSRILLFNTTGRNRGRPSLVLNSKNG----LDLNCGSFNPATN--EFICCLSNFIEFFSSSGKKHQFAFDLSLRKRIFCVDKDHILIVTEETGVPTTSISVNELSPTIINRIFIIDAKNKIISLNFVVSSAIIDIFSTSQSGKNITYLLTSEGVMHRITPKSLENQINIIIQKELYPFALQLAKQHSLSPL-DVQEIHKKYGDYLFKKGLRKEATDQYIQCLDVVETSEIISKFGVKEVPDPESMRNLADYLWSLIKNSISQRDHVTLLLIVLIKLKDVEGIDTFIQHFDRKGIWNEGVVMDDMDDVTFFYSDNDFFDLDLILELMKESDFKRLSYRLAKKYSKDS---LIIVDILLNLLHNPVKAIKYIKSLPIDETLRCLVTYSKKLLEESPNETNALLIEVFTGKFKPSTFEVDLDRRDTTGDFSENIRTVFYSYKTFFNYMNSNGTSDAMSESSEASHEHEEPTYHPPKPSIVFSSFVTKPFEFVVFLEACLACYQQYEGFDEDRQVILTTLYDLYLN-LAQNDVPERIDDWRSRATGVLRESNKLVYSAASNNTSKRVDNSIMLLISHMDQSSASAKDKTKIDIASFANDNPEMDLLSTFRAMTLNEEPSTCLKFLEKYGTEEPKLLQVALSYFVSNKLIFKEMGGNEVLKEKVLRPIIEGERMPLLDIIKALSRTNVAHFGLIQDIIIDHVKTEDTEIKRNEKLIESYDKELKEKNKKLKNTINSDQPLHVPLKNQTCFMCRLTLDIPVVFFKCGHIYHQHCLNEEEDTLESERKLFKCPKCLVDLETSNKLFEAQHEVVEKNDLLNFALNSEEGSRDRFKVITEFLGRGAISYSDITI----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8SX81-1", "uniprot_id": "VPS11_DROME", "id": "Q8SX81-1", "name": "Vacuolar protein sorting-associated protein 11 homolog", "aln": "MDISVFEWKKVDLFNIIVVPFVKIP-----------NTAEISCYCFPESKSSTEERNIKLVICDKNRNILIYLSNWECITFKSPSTRKAIALCSLTSNNSLATVTPDINNGIHIDIFDLNRLTKKQAAPIIASAYTQPSSTPLCLNADVIDDKLFALAIGLGNGDILLHYGKITKNFSANIRQHTVSGNAVNGIHFDFKTQPLDTTQIMFVTCVQGVYCFMLKEKCIMDTKFVLDNDKGNLNYRSIMCKAGGGEINDSMLVVGRADAVYCYTPEGRGPCFAIEG--AKECLAWVGHYLIVGVKNSNLKQN---ATTLIVLDTENKIIVFQRQFQELFYVISENNFCYIVTNSGD--------TDACNMLMLEKNSIDVNIRLLVEKHMYNIALRLLHREGYTSSPETALVRFQYGNHLLQKGDFSRATQEFIKTIGFIKPYAVISKL-----LYSRYNTYLLNYLTEWKKKNESSSCHTRLIECCIKRDQ--------------------------------------------IEHEMQQDDFKHYKSPAKIKHLATLSKMYFACTPSNQVPVEEEHLLHQLLEYGPASLAVDLTTYLNNITFENVKESKNILS--------------------------------------------------------------------------FCSILADHNDYCAKMLAKIIEAFPVCD------EKLLFYLLVFYFKLWRLDKVTS------SFVSDFIKTHS------------LRMDKTIIVSRLYTFFNVT-----------------------------------QRIHGHQKNTGTLHNETIDKCIENLIKNNPDVALN--------------ENLSKRSFLMMLKSSCSTEEIKAIKIKPIFKDRLLRSIVDSANELKLVENFN----EKIKRSRSMLSLYTNNPIEFRNDKCDICREMLSMQSIYFLCQHSFHEECLNYKSTKRQ-----EKFLCIICKTRNLLSPKHSSNFSCDSSDTIAVLAKIVS---IGNKLETKLMIRGRQKSDGVTCNPFN------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .*::. :*: : . : : :.. . :: . *:: . . . . : ::.*:: . .. . :. : :.* :.:*: :*.: * *.*::: :: . : . *.. . : : . : * . :* : * : : :: : : : .. : **:: * :::: .. . . :. : : . . :.: . * : : :. : ::.::.:*.:: :*:.* : . : :**::* ** . * :::*: :. ::. :* *: .. * ** ::. :. *. *: : : . ::: .: .: : : . :: : . : * : : . :.:. :* . . :. : :* : : * : :: :. . . ..:: .*::::: : . :. * . : .: : :: : . . * :::: . .. *: : ::: . : .: :. : *: : :. :. ::: .* :*. *.: :.* * * :*:.*:: . . . .. . .:.. : * : . . .: :. : ** . : ", "identical_positions": 55, "similar_positions": 266, "identity": "5.06%" }, { "cls_id": "homologset.agr.SGD:S000004846", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VZY0-1", "uniprot_id": "Q9VZY0_DROME", "id": "Q9VZY0-1", "name": "", "aln": "MSDISSEDLRREIQAVLKDADLATISAKRVREQVEGKLNCSLLSRKKEFDKIVMEVINEQQDEEDEDDDEGKDPDADPDDESEPSEEEDPSSSEEEAAKKKKQSPKKRPQPTKHKAPKKKRKTLNADDSGTESDAGSDSDYEVVKKPAAKKKAKAAGGTGSGRKSTGFTRAYNLSPELSALMGESSLPRHEVVKKVWAIIKERDLYDPKNKQFAICDDELMKVMKIRRFRTFGMLKHLKPHFLD-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05024-1", "uniprot_id": "TRI1_YEAST", "id": "Q05024-1", "name": "Protein TRI1", "aln": "MADIN--KYIPMVDAILSVSNPDEISPKRVRKALQILYSVNLDSQRKLINELILERFGDIQE----------NPRVLIPKNDLISRDQELSLRLQKEEERPLRSTRKRKGKSESKSKRKKKKNDSPDSNSIS------------------------------------VRKVLLSAPLQKFLGSEELPRTQVVKMIWQYIKEHDLQNPKDRREILCDEKMEPIFG-KKMTMFSMNKLLTKHLFNPDEIVKHEEEQKQTPEKEIKLENESLPNLSG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:**. . ::*:*. :: **.****: :: . .* *::* ::::::* :.: *: :* . .:. *.::: * :: :: :*.:** :: *: :**:*. ..*... . .* **. *. ::*...*** :*** :* ***:** :**::: :**::: :: ::: *.* * *. *::: ", "identical_positions": 53, "similar_positions": 84, "identity": "19.27%" }, { "cls_id": "homologset.agr.SGD:S000004847", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BK46-1", "uniprot_id": "RNH1_RAT", "id": "Q5BK46-1", "name": "Ribonuclease H1", "aln": "MRWLLPLFRTVTLAVVRVRRGVCGLG-MFYAVRRGRRTGVFLSWSECKAQVDRFPAARFKKFATEDEAWAFVRSSSSPDGSKGQESAHVQKLQVK------------------------------------------------------------TSKRPREPL-GEEEEPPEPGAKHTRQDTEPAALVSKDAFS---------YMGESVVVYTDGCCSSNGRKRARAGIGVYWGPGHPLNVGIRLP-GRQTNQRAEIHAACKAITQAKAQNIS-----KLVLYTDSMFTINGITNWVQGWKKNGWRTSTGKDVIN----------KEDFMELDELTQGMDIQWMHIPGHSGFVGNEEADRLAREGAKQSEG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70338-1", "uniprot_id": "RNH1_MOUSE", "id": "O70338-1", "name": "Ribonuclease H1", "aln": "MRWLLPLSRTVTLAVVRLRRGICGLG-MFYAVRRGRRTGVFLSWSECKAQVDRFPAARFKKFATEDEAWAFVRSSSSPDGSKGQESAHEQKSQAK------------------------------------------------------------TSKRPREPL-GEGEELPEPGPKHTRQDTEPAAVVSKDTFS---------YMGESVIVYTDGCCSSNGRKRARAGIGVYWGPGHPLNVGIRLP-GRQTNQRAEIHAACKAIMQAKAQNIS-----KLVLYTDSMFTINGITNWVQGWKKNGWRTSTGKDVIN----------KEDFMELDELTQGMDIQWMHIPGHSGFVGNEEADRLAREGAKQSED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60930-1", "uniprot_id": "RNH1_HUMAN", "id": "O60930-1", "name": "Ribonuclease H1", "aln": "MSWLLFLAHRVALAALPCRRGSRGFG-MFYAVRRGRKTGVFLTWNECRAQVDRFPAARFKKFATEDEAWAFVRKSASPEVSEGHENQHGQESEAK------------------------------------------------------------ASKRLREPLDGDGHESAEPYAKHMKPSVEPAPPVSRDTFS---------YMGDFVVVYTDGCCSSNGRRRPRAGIGVYWGPGHPLNVGIRLP-GRQTNQRAEIHAACKAIEQAKTQNIN-----KLVLYTDSMFTINGITNWVQGWKKNGWKTSAGKEVIN----------KEDFVALERLTQGMDIQWMHVPGHSGFIGNEEADRLAREGAKQSED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N0V4-1", "uniprot_id": "A0A8M1N0V4_DANRE", "id": "A0A8M1N0V4-1", "name": "Ribonuclease H1", "aln": "MLRLPGFLNVVRRTLCNAAEEMGKKGNFFYAVRKGFKPGVYQTWEECKHQVDKFPSASFKKFASEQDALDFVRSHSDASSSAGANGCELEVLPPRNVPCSSM-------------------------------------------------AVSFGSKRTHDETEDEGPSCPKR-VKLIEVPQPKTGTTSSDGFT---------YMGDAVVVYTDGCCSGNGKHGARAGIGVYWGRDHPRNVAERLP-GRQTNQRAELQAACKALEQAKEMNFK-----KVVLYTDSKFTINGVTSWVKTWKSNGWRLKSGGVIIN----------KDDFQQLDKLNAELDVVWMHIPGHAGYTGNEEADRLSREGAAKPTC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04740-1", "uniprot_id": "RNH1_YEAST", "id": "Q04740-1", "name": "Ribonuclease H", "aln": "---------------------MARQG-NFYAVRKGRETGIYNTWNECKNQVDGYGGAIYKKFNSYEQAKSFLGQPNTTSNYGSSTHAGGQVSKPHTTQKRVHRRNRPLHYSSLTSSSACSSLSSANTNTFYSVKSNVPNIESKIFNNWKDCQAYVKHKRGITFKKFEDQLAAENFISGMSAHDYKLMNISKESFESKYKLSSNTMYNKSMNVYCDGSSFGNGTSSSRAGYGAYFEGAPEENISEPLLSGAQTNNRAEIEAVSEALKKIWEKLTNEKEKVNYQIKTDSEYVTKLLNDRYMTYDNKKLEGLPNSDLIVPLVQRFVKVKKYYELNKECFKNNGKFQIEWVKGHDGDPGNEMADFLAKKGASRR--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *****:* ..*:: :*.**: *** : .* :*** : ::* *: . .. . : : ** : .: . * : * .. : ** **.. .** .*** *.*: *:. * * ***:***:.*..:*: : . : : *** :. : :.. :..: . .. :* * : :. .. : ** * *** ** *:::** : ", "identical_positions": 62, "similar_positions": 72, "identity": "16.67%" }, { "cls_id": "homologset.agr.SGD:S000004848", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAA5-1", "uniprot_id": "F1MAA5_RAT", "id": "F1MAA5-1", "name": "Ran GTPase-activating protein 1", "aln": "MASEDIAKLAETLAKTQVAGGQLSFKGKGLKLNTAEDAKDVIKEIEEFDGLEALRLEGNTVGVEAARVIAKALEKKSKLKR----CHWSDMFTGRLRSEIPPALISLGEGLITAGAQLVELDLSDNAFGPDGVRGFEALLKSPACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPLTLKVFVAGRNRLENDGATALAEAFGIIGT-LEEVHMPQNGINHPGVTALAQA-FAINPLLRVINLNDNTFTEKGGVAMAETLKTLR-QVEVINFGDCLVRSKGAVAIADAVRGG-LPKLKELNLSFCEIKRD---AALVVAEAVADKAELEKLDLNGNALGEEGCEQLQEVLDSFNMAKVLASLSDDEGEDEDEDEEGE-DDEDEEDEE-------EEEE--EEEEEEEEEEEPQQRGSGEEPATPSRKILDPNSGEPAPVLSSPPPTDLSTFLSFPSPE----KLLRLGPKVSVLIVQQTDTSDPEKVVSAFLKVASVFRDEASVKTAVLDAIDALMKKAFSSSSFN-SNTFLTRLLIHMGLLKSEDK-IKAIPSLHGPLMVLNHVVQQDYFPKTLAPLLLAFVTKPNGALESCSFARHSLLQTLYSI---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P46061-1", "uniprot_id": "RAGP1_MOUSE", "id": "P46061-1", "name": "Ran GTPase-activating protein 1", "aln": "MASEDIAKLAETLAKTQVAGGQLSFKGKGLKLNTAEDAKDVIKEIEEFDGLEALRLEGNTVGVEAARVIAKALEKKSELKR----CHWSDMFTGRLRSEIPPALISLGEGLITAGAQLVELDLSDNAFGPDGVRGFEALLKSPACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPLALKVFVAGRNRLENDGATALAEAFGIIGT-LEEVHMPQNGINHPGVTALAQA-FAINPLLRVINLNDNTFTEKGGVAMAETLKTLR-QVEVINFGDCLVRSKGAVAIADAVRGG-LPKLKELNLSFCEIKRD---AALVVAEAVADKAELEKLDLNGNALGEEGCEQLQEVMDSFNMAKVLASLSDDEGEDEDEEEEGEEDDEEEEDEE-------DEEDDDEEEEEQEEEEEPPQRGSGEEPATPSRKILDPNSGEPAPVLSSPTPTDLSTFLSFPSPE----KLLRLGPKVSVLIVQQTDTSDPEKVVSAFLKVASVFRDDASVKTAVLDAIDALMKKAFSCSSFN-SNTFLTRLLIHMGLLKSEDK-IKAIPSLHGPLMVLNHVVRQDYFPKALAPLLLAFVTKPNGALETCSFARHNLLQTLYNI---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46060-1", "uniprot_id": "RAGP1_HUMAN", "id": "P46060-1", "name": "Ran GTPase-activating protein 1", "aln": "MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNTVGVEAARVIAKALEKKSELKR----CHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLSDNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPLALKVFVAGRNRLENDGATALAEAFRVIGT-LEEVHMPQNGINHPGITALAQA-FAVNPLLRVINLNDNTFTEKGAVAMAETLKTLR-QVEVINFGDCLVRSKGAVAIADAIRGG-LPKLKELNLSFCEIKRD---AALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDD--EDEEEEEEGEEEEEEAEEEE-------EEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTGEPAPVLSSPPPADVSTFLAFPSPE----KLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVFKDEATVRMAVQDAVDALMQKAFNSSSFN-SNTFLTRLLVHMGLLKSEDK-VKAIANLYGPLMALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5B1-1", "uniprot_id": "A0ACD6B5B1_DANRE", "id": "A0ACD6B5B1-1", "name": "Ran GTPase-activating protein 1", "aln": "MALGDIAQITEALAKTHVGEVELSYKGRGLKLDNAESVKEIVEDIERCQGLQSLRLEGNTLGVEAADAIAKSLEAKRELEQ----CHWSDMFTGRLRSEIPPALKSLGNALMTSGARLTQLDLSDNAFGPDGVKGIENLLKSSACYTLQELRLNNCGMGSGGGVVLASALTECHKQSSAAASPLRLKVFIAGRNRLENDGATALAKAFKLLGS-LEEVHMPQNGINHPGITALAAA-LKHNPNLQVLNLNDNTFTTKGSKAMAEAIRHLQ-CLKAINFGDCLVRSEGAIAIAGALREG-LHLLRELNLSFGEICEA---AAMVVAKAVQGKADLEKLDLNGNCFGEDGCEALKEAMEKMNMEDLLCSLSDDEGEPDEEDNDDDDDDDDEEEDE-------DDDDDAEEKEGNDAEENGLNG---------TKDVIEEKE-------EPPHSSELMSFLVSPSAE----KLISLGAKRVQLIEQQVDVTDANKVSEVFLKISSVYKDEPEVKQAVFETTDALLRKAFSNSPHSQSYSFISSLMVNLGLLKSEDKKVKKVSVLPGHLLTLEHAVSQEFFPADQAGVLESFVSRNGAVLESCCSARDALKITLVKRTTA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIW3-1", "uniprot_id": "RAGP1_DROME", "id": "Q9VIW3-1", "name": "Ran GTPase-activating protein", "aln": "MSTFNFASMAAQLGQEQG----ISFENKVLSWNTAADVQDVVDALNKQTTVHYLNLDGNTLGVEAAKAIGEGLKRHPEFRK----ALWKNMFTGRLISEIPEALKHLGAALIVAGAKLTVLDLSDNALGPNGMRGLEELLRSPVCYSLQELLLCNCGLGPEGGSMLSRALIDLHANANKAGFPLQLRVFIGSRNRLEDAGATEMATAFQTLKT-FEEIVLEQNSIYIEGVEALAES-FKHNPHLRVLNMNDNTLKSEGAEKIAEALPFLP-LLREMSFGDCLIKTNGAYHFGEALERG-NERLEVIDLGFNEINSD---GGLVLVNAMGNKPKLRILNLDGNSFGEEGSEKIISEMSKLPTAAALQPFQHQEEEDLEDEYQADKQDADYEEEEEVHEHANDTTEEADEDSEGDEDDEEDEGDEEYSNVAEETAYVTTNAYTTKLFNDTTNSMASETFAVANKTISQKCTPEKFCLSQKPCSQEDFDSLDMDNKLEALQSIVNQFTGDNHLLLLVFTTLKCAHLSQSSKAALDLAVSLYQATFDYAIKTKQETR-VLNYVLMQLRLLPCKEVFHSDYDVKNCRFALREALKQPTFANDNIKNSFKTFLEGAES----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P11745-1", "uniprot_id": "RNA1_YEAST", "id": "P11745-1", "name": "Ran GTPase-activating protein 1", "aln": "MATLHFVPQHEEEQ-------VYSISGKALKLTTSDDIKPYLEELAALKTCTKLDLSGNTIGTEASEALAKCIAENTQVRESLVEVNFADLYTSRLVDEVVDSLKFLLPVLLKC-PHLEIVNLSDNAFGLRTIELLEDYIAHAVN--IKHLILSNNGMGPFAGERIGKALFHLAQNKKAASKPF-LETFICGRNRLENGSAVYLALGLKSHSEGLKVVKLYQNGIRPKGVATLIHYGLQYLKNLEILDLQDNTFTKHASLILAKALPTWKDSLFELNLNDCLLKTAGSDEVFKVFTEVKFPNLHVLKFEYNEMAQETIEVSFLPAMEKGNLPELEKLEINGNRLDEDS-----------DALDLLQSKFDDLEVDDFEEVDSEDEEGEDEEDE-------------DEDEKLEEIETER-------------------------------------------------------------LEKELLEVQVDDLAERLAETEIK-----------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .:. * ..: *. .: . : :. : * *.***:*.**: .:.: : : :... : :::*.** *: :* * *: . .:* ::*****:* :. :* : .. ::.* * * *:* .* :. ** . : . . *: *..*: .*****: .*. :* .: :: : : **.* *: :* : *.:::::***:. ... :*::: : :.:.***::: *: . .. *. :.: : *: .: . . ..*. *:::** :.*:. * . .: :: : : :: : *::* :*.. : : :: : :. . : . ", "identical_positions": 69, "similar_positions": 151, "identity": "11.2%" }, { "cls_id": "homologset.agr.SGD:S000004849", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BKE0-1", "uniprot_id": "TAF9_RAT", "id": "Q5BKE0-1", "name": "Transcription initiation factor TFIID subunit 9", "aln": "-----------MESGK------MASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKPT-----VDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRYCLTAPNYRLKSLQK----KAPTPAGRITVPRLSVGSVSSRPSTPTLGTPTPQAMSVSTKVGTPMSLTGQRFTVQMPASQS---PAVKASIPATPAVQNVLINPSLIGSKNILITTNMVS-QNTANESANALKRKREEEDDDDDDDDDD-YDNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VI33-1", "uniprot_id": "TAF9_MOUSE", "id": "Q8VI33-1", "name": "Transcription initiation factor TFIID subunit 9", "aln": "-----------MESGK------MASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKAT-----VDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRYCLTAPNYRLKSLQK----KAPAPAGRITVPRLSVGSVSSRPSTPTLGTPTPQTMSVSTKVGTPMSLTGQRFTVQMPASQS---PAVKASIPATSTVQNVLINPSLIGSKNILITTNMVS-QNTA-ESANALKRKREDDDDDDDDDDDDDYDNM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16594-1", "uniprot_id": "TAF9_HUMAN", "id": "Q16594-1", "name": "Transcription initiation factor TFIID subunit 9", "aln": "-----------MESGK------TASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKAT-----VDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRYCLTAPNYRLKSLQK----KASTSAGRITVPRLSVGSVTSRPSTPTLGTPTPQTMSVSTKVGTPMSLTGQRFTVQMPTSQS---PAVKASIPATSAVQNVLINPSLIGSKNILITTNMMSSQNTANESSNALKRKRE--DDDDDDDDDDDYDNL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NZA9-1", "uniprot_id": "TAF9B_MOUSE", "id": "Q6NZA9-1", "name": "Transcription initiation factor TFIID subunit 9B", "aln": "-----------MEPAK------MAPIKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKPT-----VDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRYCLTAPNYRLKSLVK----KGPN-QGRL-VPRLS--AVSSRPTTPPVAP--PQAVSGPNKAATPVSVTSQRFAVQIPPSQS---TPAKP-APAATAVQNVLINPSMIGPKNILITTSMVSSQNTATDS-NPLKRKHD--DDDD-------NDTM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62880-1", "uniprot_id": "TAF9B_RAT", "id": "Q62880-1", "name": "Transcription initiation factor TFIID subunit 9B", "aln": "-----------MEPSK------MAPLKNAPRDALVMAQILKDMGITDYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKPT-----VDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRYCLTAPNYRLKSLVK----KGPN-QGRL-VPRLSVGAVSSRPTTPTVAP--PQAVSVPNKVATPVSVTSQRFAVQIPTSQS---TPAKP-APAATSVQNVLINPSMIGSKNILITTNMVSSQSTATDS-NPLKRKHD--DDDDDDDDDDDNDTM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HBM6-1", "uniprot_id": "TAF9B_HUMAN", "id": "Q9HBM6-1", "name": "Transcription initiation factor TFIID subunit 9B", "aln": "-----------MESGK------MAPPKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKPN-----VDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRYCLTAPNYRLKSLIK----KGPN-QGRL-VPRLSVGAVSSKPTTPTIAT--PQTVSVPNKVATPMSVTSQRFTVQIPPSQS---TPVKP-VPATTAVQNVLINPSMIGPKNILITTNMVSSQNTANEA-NPLKRKHE--DDDD-------NDIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27272-1", "uniprot_id": "TAF9_DROME", "id": "Q27272-1", "name": "Transcription initiation factor TFIID subunit 9", "aln": "-----------MSAEKSDKAKISAQIKHVPKDAQVIMSILKELNVQEYEPRVVNQLLEFTFRYVTCILDDAKVYANHARKKT-----IDLDDVRLATEVTLDKSFTGPLERHVLAKVADVRNSMPLPPIKPHCGLRLPPDRYCLTGVNYKLRATNQPKKMTKSAVEGRPLKTVVKPVSSANGPKRPHSVVAKQQVVTIPKPVIKFTTTTTTKTVGSSGGSGGGGGQEVKSESTGAGGDLKMEVDSDAAAVGSIAGASGSGAGSASGGGGGGGSSGVGVAVKREREEEEFEFVTN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05027-1", "uniprot_id": "TAF9_YEAST", "id": "Q05027-1", "name": "SAGA complex/transcription factor TFIID complex subunit TAF9", "aln": "MNGGGKNVLNKNSVGSVSEVGPDSTQEETPRDVRLLHLLLASQSIHQYEDQVPLQLMDFAHRYTQGVLKDALVYNDYAGSGNSAGSGLGVEDIRLAIAARTQYQFKPTAPKELMLQLAAERNKKALPQVMGTWGVRLPPEKYCLTAKEWDLEDPKSM------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : *:*. :: :* . .: :** :* *:::*:.**. :*.** :* .:* . . :. :*:*** : .*. . :..: .:* :*. .** : * ****::****. :: *. . ", "identical_positions": 34, "similar_positions": 52, "identity": "11.53%" }, { "cls_id": "homologset.agr.SGD:S000004852", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5HZJ0-1", "uniprot_id": "RNC_MOUSE", "id": "Q5HZJ0-1", "name": "Ribonuclease 3", "aln": "-MQGNTCHRMSYHPGRGCPRGRGGHGARPSAPAFRPQNLRLLHPQQPPAQYQYEPPSAPSSSYSNSQAPSFMPPRPDFVPYPPPAAPSAQGPLPPCPVRPPYPNHQMRHPFPVPPCFPPMPPPMPCPNNPPASGAPPGQGTFPFMVPPPSMPHPPPPPVMPQQVNYQYPPGYSHS-FPPPGFNSYQNNSSSFPPSANSSSTPHFRHLPPYSLPKAQNERRSPERLKHYDDHRHRDHSHGRGERHRSLERRERGRSPERRRPESRYRSDYDRGRTPPPRHRSYERSRERDRERHRHREARRSPSLERSYKKEYKRSGRSYALPVAPEPAGCTPELPGEMIKTTESWAPPPENVNHRSPSREKKRARWEEEKDRWSDSQGSGKEKNYTSIKEKEAEEVPPEKTEEEEEELLKPVWIRCTHSESYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGNRQEKAKAARPPWEPPKTKLDEDLESSSESECETDDDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPEVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPEEAEDIKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PTR3-1", "uniprot_id": "E9PTR3_RAT", "id": "E9PTR3-1", "name": "Ribonuclease 3", "aln": "-MQGNTCHRMSYHPGRGCPRGRGGHGARPSAPTYRPQNLRLLHPQQPPAQYQYEPPSAPSSSFSNSQAPNFMPPRPDFVPYPPPVAPSAQGPLPPCPVRPPYPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVSGAPPGQGTFPFMVPPPSMPHPPPPPVMPQQVNYQYPPGYSHS-FPPPNFNSFQNNSSSFPPSANNSSTPHFRHLPPYSLPKAQSERRSPERLKHYDDHRHRDHSHGRGERHRSLERRERGRSPERRRPESRYRSEYDRGRTPPPRHRSYERSRERERERHRHRENRRSPSLERAYKKEYKRSGRSYGLPVTPEPAGCTAELPGEIIKNTDSWAPPQENVNHRSPSREKKRARWEEEKDRWSDSQSSGKEKSYTSIKEKEPEEAPPEKTEEEDEELLKPVWIRCTHSESYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGNRQEKAKAARPPWEPPKTKLDEDLESSSESECETDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPEVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGTLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDEAEDIKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NRR4-1", "uniprot_id": "RNC_HUMAN", "id": "Q9NRR4-1", "name": "Ribonuclease 3", "aln": "MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTP-SRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGRSYGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESSSESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02555-1", "uniprot_id": "RNT1_YEAST", "id": "Q02555-1", "name": "Ribonuclease 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSKVAGKKKTQNDNKLDNENGSQQRENINTKTLLKG-------NLKISNYKYLEVIQLEHAVTK----------LVESYNKIIELSPNLVAYN------EAVNNQDRVPVQILPSLSRYQLKLAAELKTLHDLKKDAILTE---------ITDYENEFDTEQKQPILQEIS---------------------------------------------KADMEKLEKLEQVKREKREKIDVNVYENLNEKEDEEEDEGEDSYDP------------------TKAGDIVKATKWP------------PKLPEIQDLAIRAR-----VFIHKSTIKDKVYLSGS-------------------------------------------------------------------------------------------------------EMIN------------AHNERLEFLGDSILNSVMTLIIYNKFPDYSEGQLSTLRMNLVSNEQIKQWS--------IMYNFHEKLKTNFDLKDENSN---------FQNGKLKLYADVFEAYIGG---------------LMEDDPRNN-------------------LPKIRKWLRKLAKPVIEEAT-------------------------------------RNQVALEKTDKLDMNAKRQLYSLIGYASLRLHYVTVKKPTAVDPNSIVECRVG---------------------------------------------------------------------------------DGTVLGTGVGRNIKIAGIRAAENALRDKKMLDFYAKQRAAIPRSESVLKDP--SQKNKKRKFSDTS----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . *:*. : ::*.:* :: ::* .* * .:: * * *.*: :.:*: *.. .::: *.:: *: *... :.*: :* . :::: :: :.:: : : .: : * : :* : * *:::: . *:* : *:** * :. * : . . : .. . :: ..:.::* : *** . * **: : :. : * : :*.*:: :* :. * :::. **********:::: : :: :* **. .** *:* * :*.*::: : ::* . .* : **:. :* : :*.*: ::* : . * ::*..: : * . :* **:.. .:. ..:::* ::. :: .:: :: . :* . : ..*:*.*: .:::.: . .* :* * * .*: * : ** :**.. :: :: ::* : .. **: .:::::*: .::. ", "identical_positions": 94, "similar_positions": 211, "identity": "6.84%" }, { "cls_id": "homologset.agr.SGD:S000004853", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZMS1-1", "uniprot_id": "D3ZMS1_RAT", "id": "D3ZMS1-1", "name": "", "aln": "MAAEHPEPPKGELQLPPPPPPGHYGAWAAQELQAKLAEIGAPIQGSREELVERLQTYTRQTGIVLNRPVLRGEDGDKAAPPPMSAQLSGIPMPPPPLGLPPLQPPPPPPPPPPGLGLGFPMAHPPNLGPPPPLRVGEPVALSEEERLKLAQQQAALLMQQEERAKQ-----------------AAVLMEQERQQEIAKMGTAVPRPPQDMGQLGVRTPLGPRVAAPVGPVVPTPTVLPMGAPVPRPRGPPPPPGDENREMDDPSVGPKIPQALEKILQLKESRQEEMNSQQEEEEMETDTRSSLGQSASETEEDTVSTSKKEKNRKRRNRKKKKKPQRVRAASSESSGDREKDSARSRGSDSPAADVEIEYVTEEPEIYEPN--FIFFKRIFEAFKLTDDVKKEKEKEPEKLDKMENSAVPKKKGFEEEHKDSDDDSSDDEQEKKPEAPKLSKKKLRRMNRFTVAELKQLVARPDVVEMHDVTAQDPKLLVHLKATRNSVPVPRHWCFKRKYLQGKRGIEKPPFELPDFIKRTGIQEMREALQEK----EEQKTMKSKMREKVRPKMGKIDIDYQKLHDAFFKWQT---KPKLTIHGDLYYEGK------EFETRLKEKKPGDLSDELRISLGMPVGPNAHKVPPPWLIAMQRYGPPPSYPNLKIPGLNSPIPESCSFGYHAGGWGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRTPWGELEPSDEESSEEEEEEESDE-DKPDETGFITPADSGLITPGGFSSVPAGMETPELIELRKKKIEEAMDGSETPQLFTVLPEKRTATVGGAMMGSTHIYDMSTVMSRKGPAPELQG-----VEVALAPEELELDPMAMTQKYEEHVREQQAQVEKEDFSDMVAEHAAKQKQKKRKAQPQDSRGGSKKYKEFKF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UJB0-1", "uniprot_id": "SF3B2_MOUSE", "id": "Q3UJB0-1", "name": "Splicing factor 3B subunit 2", "aln": "MAAEHPEPPKGELQLPPPPPPGHYGAWAAQELQARLAEIGAPIQGSREELVERLQTYTRQTGIVLNRPVLRGEDGDKAAPPPMSAQLSGIPMPPPPMGLPPLQPPPPPPPPPPGLGLGFPMAHPPNLGPPPPLRVGEPVALSEEERLKLAQQQAALLMQQEERAKQ-----------------AAVLMEQERQQEIAKMGTAVPRPPQDMGQLGVRTPLGPRVAAPVGPVVPTPTVLPMGAPVPRPRGPPPPPGDENREMDDPSVGPKIPQALEKILQLKESRQEEMNSQQEEEEMETDTRSSLGQSASETEEDTVSISKKEKNRKRRNRKKKKKPQRVRAASSESSGDREKDSGRSRGSDPPAADVEIEYVTEEPEIYEPN--FIFFKRIFEAFKLTDDVKKEKEKEPEKLDKMESSAVPKKKGFEEEHKDSDDDSSDDEQEKKPEAPKLSKKKLRRMNRFTVAELKQLVARPDVVEMHDVTAQDPKLLVHLKATRNSVPVPRHWCFKRKYLQGKRGIEKPPFELPDFIKRTGIQEMREALQEK----EEQKTMKSKMREKVRPKMGKIDIDYQKLHDAFFKWQT---KPKLTIHGDLYYEGK------EFETRLKEKKPGDLSDELRISLGMPVGPNAHKVPPPWLIAMQRYGPPPSYPNLKIPGLNSPIPESCSFGYHAGGWGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRTPWGELEPSDEESSEEEEEEESDE-DKPDETGFITPADSGLITPGGFSSVPAGMETPELIELRKKKIEEAMDGSETPQLFTVLPEKRTATVGGAMMGSTHIYDMSTVMSRKGPAPELQG-----VEVALAPEELELDPMAMTQKYEEHVREQQAQVEKEDFSDMVAEHAAKQKQKKRKAQPQDSRGGSKKYKEFKF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13435-1", "uniprot_id": "SF3B2_HUMAN", "id": "Q13435-1", "name": "Splicing factor 3B subunit 2", "aln": "MATEHPEPPKAELQLPPPPPPGHYGAWAAQELQAKLAEIGAPIQGNREELVERLQSYTRQTGIVLNRPVLRGEDGDKAAPPPMSAQLPGIPMPPPPLGLPPLQPPPPPPPPPPGLGLGFPMAHPPNLGPPPPLRVGEPVALSEEERLKLAQQQAALLMQQEERAKQQGDHSLKEHELLEQQKRAAVLLEQERQQEIAKMGTPVPRPPQDMGQIGVRTPLGPRVAAPVGPVGPTPTVLPMGAPVPRPRGPPPPPGDENREMDDPSVGPKIPQALEKILQLKESRQEEMNSQQEEEEMETDARSSLGQSASETEEDTVSVSKKEKNRKRRNRKKKKKPQRVRGVSSESSGDREKDSTRSRGSDSPAADVEIEYVTEEPEIYEPN--FIFFKRIFEAFKLTDDVKKEKEKEPEKLDKLENSAAPKKKGFEEEHKDSDDDSSDDEQEKKPEAPKLSKKKLRRMNRFTVAELKQLVARPDVVEMHDVTAQDPKLLVHLKATRNSVPVPRHWCFKRKYLQGKRGIEKPPFELPDFIKRTGIQEMREALQEK----EEQKTMKSKMREKVRPKMGKIDIDYQKLHDAFFKWQT---KPKLTIHGDLYYEGK------EFETRLKEKKPGDLSDELRISLGMPVGPNAHKVPPPWLIAMQRYGPPPSYPNLKIPGLNSPIPESCSFGYHAGGWGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRTPWGELEPSDEESSEEEEEEESDE-DKPDETGFITPADSGLITPGGFSSVPAGMETPELIELRKKKIEEAMDGSETPQLFTVLPEKRTATVGGAMMGSTHIYDMSTVMSRKGPAPELQG-----VEVALAPEELELDPMAMTQKYEEHVREQQAQVEKEDFSDMVAEHAAKQKQKKRKAQPQDSRGGSKKYKEFKF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQK7-1", "uniprot_id": "Q9VQK7_DROME", "id": "Q9VQK7-1", "name": "", "aln": "MADQLNNEPG-------QPTPLMSIRFDQQQHESAAANGNENGNGNAN------------------------GDGDASEDAVDAEKTPGELVLPKAL----------------------------------------------EDVLALKDQRAAEFTVDAD----------------------------------------------SQGGSGGATQDGD--EADVGEDSEEDADNQVNGSASQKTGKQSKAERNKKKKKRKKQNRKIRHQIEFARQQQLAQAEEN--EPEAKDSETKAHGSEDEQVAEKE-------KKDKRKESRSKRRKDRSD-------------EKDTDKKAG-EANDENVTIEYVPEKITIADLAPMYRQFYRVFEIFKLEN---KPKPVEKDKSSHDSESHPRDKKATDKQLEDEDDDGDDDE-ERKEDKEKLSKRKLKKLTRLSVAELKQLVSRPDVVEMHDVTARDPKLLVQLKAYRNTVQVPRHWCFKRKYLQGKRGIEKPPFDLPAFIKKTGIMEMRESLQER----EDAKTLKAKMRERVRPKMGKIDIDYQKLHDAFFKWQT---KPRMTIHGDLYYEGK------EFETRLKEKKPGDLSEELRIALGMPVGPNSHKIPPPWLIAQQRYGPPPSYPNLKIPGLNAPIPDGTSFGYHAGGWGKPPVDENGKPLYGDVFGTNILDLDNGVDEADIERNQWGELESESEESSEEEEEDGEDLGDQQDETGLVTPVEG-LVTPSGLTSVPAGMETPENIELRKKKIEAEMEDNETPVLYQVLPEKRTDRIGASMMGSTHVYDVSGSGANKQPPVRSTTDREGIVELALDPSELDLDNDAMAQRYEQQMREQQNHLQKEDLSDMLAEHVARQKSK-RKRQQTDPAKTTKKYKEFKF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02554-1", "uniprot_id": "CUS1_YEAST", "id": "Q02554-1", "name": "Cold sensitive U2 snRNA suppressor 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARTKSRKRSGNNQNKNASVVNNKAEIAAMIDARRLEQ---------------------------------------------------------------------------KKKGGVTNSKGKTNKVVDAKLEK--------EFKDVLQRFQVQE---NDTPKEITKDEKNNHVVIVEKNPVMNRKHTAEDELEDTPSDGIEEH--LSARKRRKTEKPSLSQLKSQVPYPQIIEWYDCDARYPGLLASIKCTKNVIPVPSHWQSKKEYLSGRSLLGKRPFELPDIIKKTNIEQMRSTLPQSGLDGQDEKSLKEASRARVQPKMGALDLDYKKLHDVFFKIGANWKPDHLLCFGDVYYENRNLFEETNWKRMVDHKRPGRISQELRAIMNLPEGQ-----LPPWCMKMKDIGLPTGYPDLKIAGLNWDITN----------------------LKGDVYGKIIPNHHSRSKKQ--GRNYFGALISFETPEFENSKEDTQAN------------------------------------------------------------------------------------------------------------------------AENGRQDDKIDDEVEHKLDHFQEDISEVTSAEEKLERNEEESEKQLYTVLK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . :::: . . :* :: : :. * . . : * : * ::: *:: : : . * * .: . .*: :. . :*: .* : : ** :* :: : ::::**. *. *:::* :* *: * **. :*. :* : ** ** *::**.*: : * **:** :**:*.* :**.:* : :: *::* * :*:**** :*:**:****.*** : :: .**:***.: ::: :..*:** :*:*** :.:* * *** : : * *..**:***.*** *.: * ***:*. : .. .: *. :* * . . . *:.:*: . *: :::: . : *. * . *. :. .. .* : : .: *. :* ", "identical_positions": 108, "similar_positions": 148, "identity": "11.79%" }, { "cls_id": "homologset.agr.SGD:S000004855", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62718-1", "uniprot_id": "RL18A_RAT", "id": "P62718-1", "name": "Large ribosomal subunit protein eL20", "aln": "MKASGTLREYKVVGRCLPTPKCHTPPLYRMRIFAPNHVVAKSRFWYFVSQLKKMKKSSGEIVYCGQVFEKSPLRVKNFGIWLRYDSRSGTHNMYREYRDLTTAGAVTQCYRDMGARHRARAHSIQIMKVEEIA-AGKCRRPAVKQFHDSKIKFPLPHRVLRRQHKPRFTTKRPNTFF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62717-1", "uniprot_id": "RL18A_MOUSE", "id": "P62717-1", "name": "Large ribosomal subunit protein eL20", "aln": "MKASGTLREYKVVGRCLPTPKCHTPPLYRMRIFAPNHVVAKSRFWYFVSQLKKMKKSSGEIVYCGQVFEKSPLRVKNFGIWLRYDSRSGTHNMYREYRDLTTAGAVTQCYRDMGARHRARAHSIQIMKVEEIA-AGKCRRPAVKQFHDSKIKFPLPHRVLRRQHKPRFTTKRPNTFF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02543-1", "uniprot_id": "RL18A_HUMAN", "id": "Q02543-1", "name": "Large ribosomal subunit protein eL20", "aln": "MKASGTLREYKVVGRCLPTPKCHTPPLYRMRIFAPNHVVAKSRFWYFVSQLKKMKKSSGEIVYCGQVFEKSPLRVKNFGIWLRYDSRSGTHNMYREYRDLTTAGAVTQCYRDMGARHRARAHSIQIMKVEEIA-ASKCRRPAVKQFHDSKIKFPLPHRVLRRQHKPRFTTKRPNTFF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZWJ4-1", "uniprot_id": "RL18A_DANRE", "id": "Q7ZWJ4-1", "name": "Large ribosomal subunit protein eL20", "aln": "MKASGTLREYKVVGRLLPSVKNPAPPLYRMRIFAPNHVVAKSRFWYFVSQLRKMKKASGEIVYCGLVFEKSPLKVKNFGIWLRYDSRSGTHNMYREYRDLTTSGAVTQCYRDMGARHRARAHAIQIMKVQVIA-ANKCRRPAIKQFHDSKIKFPLPHRVLRRQHKPRFTTKRPNTFF-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41093-1", "uniprot_id": "RL18A_DROME", "id": "P41093-1", "name": "Large ribosomal subunit protein eL20", "aln": "MRAKGLLKEYEVVGRKLPSEKEPQTPLYKMRIFAPDNIVAKSRFWYFLRQLKKFKKTTGEIVSIKQVYETSPVKIKNFGIWLRYDSRSGTHNMYREYRDLTVGGAVTQCYRDMGARHRARAHSIQIIKVDSIP-AAKTRRVHVKQFHDSKIKFPLVQRVHHKGNRKLFSFRKPRTYFQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX23-1", "uniprot_id": "RL20A_YEAST", "id": "P0CX23-1", "name": "Large ribosomal subunit protein eL20A", "aln": "---MAHFKEYQVIGRRLPTESVPEPKLFRMRIFASNEVIAKSRYWYFLQKLHKVKKASGEIVSINQINEAHPTKVKNFGVWVRYDSRSGTHNMYKEIRDVSRVAAVETLYQDMAARHRARFRSIHILKVAEIEKTADVKRQYVKQFLTKDLKFPLPHRVQKS--TKTFSYKRPSTFY-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::**:*:** **: . . *::*****.:.::****:***: :*:*.**::**** : * * ::****:*:************:* **:: .** *:**.****** ::*:*:** * : . :* :*** ..:**** :** : *: ::* *:: ", "identical_positions": 79, "similar_positions": 51, "identity": "44.38%" }, { "cls_id": "homologset.agr.SGD:S000004856", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62720-1", "uniprot_id": "ZNT1_RAT", "id": "Q62720-1", "name": "Proton-coupled zinc antiporter SLC30A1", "aln": "---MGCWGRNRGRLLCMLLLTFMFMVLEVVVSRVTASLAMLSDSFHMLSDVLALVVALVAERFARRTHATQ------------------------------------KNTFGWIRAEVMGALVNAIFLTGLCFAILLEAVERFIEP---HEMQQPLVVLSVGVAGLLVNVLGLCLFHHHSGEGQGAGHGHSHG-HGHGH-LAKGAR--KAGRAG-GEAGAPPG-RAPDQEPDQEETNTLVANTSNSNGLKADQAEP--EKLRSDDPVDVQVNGNLIQESDSLESEDNRAGQLNMRGVFLHVLGDALGSVIVVVNALVFYFSWKGCTEDDFCVNPCFPDPCKSSVELMNS--TQAPMHEAGPCWVLYLDPTLCIIMVCILLYTTYPLLKESALILLQTVPKQIDIKHLVKELRD-VEGVEEVHELHVWQLAGSRIIATAHIKCEDPA----SYMQVAKTIKDVFHNHGIHATTIQPEFAS---------------------------------------VGSKSSVVPCELACRTQCALKQCCGTRPQVHSGKEAEKAPTVSISCLELSENLEKK-------PRRTKAEGSVPAVVIEIKNVPNKQPESSL--------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60738-1", "uniprot_id": "ZNT1_MOUSE", "id": "Q60738-1", "name": "Proton-coupled zinc antiporter SLC30A1", "aln": "---MGCWGRNRGRLLCMLLLTFMFMVLEVVVSRVTASLAMLSDSFHMLSDVLALVVALVAERFARRTHATQ------------------------------------KNTFGWIRAEVMGALVNAIFLTGLCFAILLEAVERFIEP---HEMQQPLVVLSVGVAGLLVNVLGLCLFHHHSGEGQGAGHGHSHG-HGHGH-LAKGAR--KAGRAG-VEAGAPPG-RAPDQ----EETNTLVANTSNSNGLKADQAEP--EKLRSDDPVDVQVNGNLIQESDNLEAEDNRAGQLNMRGVFLHVLGDALGSVIVVVNALVFYFNWKGCTEDDFCTNPCFPDPCKSSVEIINS--TQAPMRDAGPCWVLYLDPTLCIIMVCILLYTTYPLLKESALILLQTVPKQIDIKHLVKELRD-VDGVEEVHELHVWQLAGSRIIATAHIKCEDPA----SYMQVAKTIKDVFHNHGIHATTIQPEFAS---------------------------------------VGSKSSVLPCELACRTQCALKQCCGTRPQVHSGKDAEKAPTVSISCLELSENLEKK-------ARRTKAEGSLPAVVIEIKNVPNKQPESSL--------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6M5-1", "uniprot_id": "ZNT1_HUMAN", "id": "Q9Y6M5-1", "name": "Proton-coupled zinc antiporter SLC30A1", "aln": "---MGCWGRNRGRLLCMLALTFMFMVLEVVVSRVTSSLAMLSDSFHMLSDVLALVVALVAERFARRTHATQ------------------------------------KNTFGWIRAEVMGALVNAIFLTGLCFAILLEAIERFIEP---HEMQQPLVVLGVGVAGLLVNVLGLCLFHHHSGFSQDSGHGHSHGGHGHGHGLPKGPRV-KSTRPGSSDINVAPGEQGPDQ----EETNTLVANTSNSNGLKLDPADP--ENPRSGDTVEVQVNGNLVREPDHMELEEDRAGQLNMRGVFLHVLGDALGSVIVVVNALVFYFSWKGCSEGDFCVNPCFPDPCKAFVEIINS--THASVYEAGPCWVLYLDPTLCVVMVCILLYTTYPLLKESALILLQTVPKQIDIRNLIKELRN-VEGVEEVHELHVWQLAGSRIIATAHIKCEDPT----SYMEVAKTIKDVFHNHGIHATTIQPEFAS---------------------------------------VGSKSSVVPCELACRTQCALKQCCGTLPQAPSGKDAEKTPAVSISCLELSNNLEKK-------PRRTKAEN-IPAVVIEIKNMPNKQPESSL--------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B789-1", "uniprot_id": "A0A8M2B789_DANRE", "id": "A0A8M2B789-1", "name": "", "aln": "---MACAP-NRVRLLCMLSLTFGFFIVEVVVSRITSSLAMLSDSFHMLSDVIALVVALVAVRFAEQTQSTN------------------------------------KNTFGWIRAEVMGALVNAVFLTALCFTIILEAIERFTEP---HEIEQPWVVIGVGALGLLVNLLGLCLFHGHAG---GGGHGHSHGGHGHSHGGAKKHKNGKVRRSETLEDSRSAG----------EETNNLVANHNSPNGVNAERKAAGKWDMCHSDSLDLQING--SAPYDELENGHDAASQLNMRGVFLHVLGDALGSVIVVINAIIFVFVWKPCEPGTICENPCSGQHCADHALNISSPLTNGTLIKAGPCWVLYLDPTLCIIMVCILLYTTYPLLKESALILLQTVPKQIDMHQLNARLRD-LEGVLAVHELHIWQLAGSRIIATAHIKCHDPT----SYMDVAKRIKDFFHDEGIHATTIQPEFVT---------------------------------------VNSESRASLCELSCRTQCAPKLCCG---AVDTAKPLEGSLESKKSCESKTPTLPSAS----VTSLEIISESVEDTSRPESVVIITREVESSL--------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3UVU3-1", "uniprot_id": "ZNT10_MOUSE", "id": "Q3UVU3-1", "name": "Calcium/manganese antiporter SLC30A10", "aln": "---MGRYSGKTCRLLFMLVLTAAFFVAELVSGYLGNSIALLSDSFNMLSDLISLCVGLGSGYIARRGPRGS------------------------------------SATYGYVRAEVVGALSNAVFLTALCFTIFVEAVLRLARP---ERIDDPELVLIVGALGLAVNVVGLLIFQ-------DCGACFSRCTRGR--RTRPSQQPSQGDPRGALGCP-------------QEAATATAPGSGTAVTLRGSSAGRKQQEGATVFSNVAGDSLNTENEPEETTKKEKKSEALNIRGVLLHVMGDALGSVVVVITAIIFYVQPLRRE------DPCN--------------------------WQCYIDPSLTVVMVIIILSSAFPLIKETAVILLQMVPKGVNMEELMSQLST-VPGISSVHEVHIWELISGKIIATLHIKHQKGT----EYQDASRKIREIFHHAGIHNVTIQFETLD---------------------------------------LKEALEQKDFLLTCSAPCITQSCAKKLCCPPGTLPLALVNGCAEHNGRSSRESYRS-----IEAPEVAIDV--DGCPREQGQTLSKTQERQHYENSTHF-------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZJB7-1", "uniprot_id": "D3ZJB7_RAT", "id": "D3ZJB7-1", "name": "", "aln": "---MGRYSGKTCRLLFMLVLTAAFFVAELVSGYLGNSIALLSDSFNMLSDLISLCVGLGSGYIARRGPRGS------------------------------------SATYGYVRAEVVGALSNAVFLTALCFTIFVEAVLRLARP---ERIDDPELVLIVGALGLAVNVVGLLIFQ-------DCGACFSRCTRGH--RTRPSQPPRQGDTGGALGCP-------------REAATATDPGSDSAVTLRGASAGRKQQEGATVFSNVAGDSLNTQNEPEETTKKEKKSEALNIRGVLLHVMGDALGSVIVVVTAIIFYVRPLRHE------DPCN--------------------------WQCYIDPSLTVVMVIIILSSAFPLIKETAVILLQMVPKGVNMEELMSQLSM-VPGVSSVHEVHIWELISGKVIATLHIKHQEGT----EYQDASRKVREIFHHAGIHNVTIQFETLD---------------------------------------LKEALEQKDFLPTCSAPCISQSCAKKLCCPPGTLPLALVNGCAEHNGGPNLESYRS-----IEAPEVVIDVALDGCPRKQGQVHSKTQERQHCENSTHF-------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6XR72-4", "uniprot_id": "ZNT10_HUMAN", "id": "Q6XR72-4", "name": "Calcium/manganese antiporter SLC30A10", "aln": "---MGRYSGKTCRLLFMLVLTVAFFVAELVSGYLGNSIALLSDSFNMLSDLISLCVGLSAGYIARRPTRGF------------------------------------SATYGYARAEVVGALSNAVFLTALCFTIFVEAVLRLARP---ERIDDPELVLIVGVLGLLVNVVGLLIFQ-------DCAAWFACCLRGRSRRLQQRQQLAEGCVPGAFGGPQGAE-------DPRRAADPTAPGSDSAVTLRGTSVERKREKGATVFANVAGDSFNTQNEPEDMMKKEKKSEALNIRGVLLHVMGDALGSVVVVITAIIFYVLPLKSE------DPCN--------------------------WQCYIDPSLTVLMVIIILSSAFPLIKETAAILLQMVPKGVNMEELMSKLSA-VPGISSVHEVHIWELVSGKIIATLHIKYPKDR----GYQDASTKIREIFHHAGIHNVTIQFENVD---------------------------------------LKEPLEQKDLLLLCNSPCISKGCAKQLCCPPGALPLAHVNGCAEHNGGPSLDTYGSDGLSRRDAREVAIEVSLDSCLSDHGQSLNKTQEDQCYVNRTHF-------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IEQ2-1", "uniprot_id": "A0A0R4IEQ2_DANRE", "id": "A0A0R4IEQ2-1", "name": "", "aln": "---MGRYSGKTCRLILMLVITVIFFVAEIVAGYMGNSVALVSDSFNMLSDILSLCVGLTAARVSRRAGSG-------------------------------------RFSFGLGRAEVVGALANAVFLIALCFSISMESLKRLAMP---QAIDDAPLVLIVGSLGLAVNLVGLVIFQ-------DCGRLCGR--RGK---EKKREEHRE----------------------------------DREQELEQVETGLQEE------------------------KTEKDGAPLNIRGVLLHVLNDALGSVVVVVASALFYVWPLEPD------QPCN--------------------------WQCYVDPSLTLVMVIIILSSAAPLLKETTTILLQMSPEDLPVSAILESVCR-LPGVSSVHEAHVWELAKGRNVASLHVKLQAPAGALWAQVSLQQQITQIFHRAGVHSLTLQLELAD---------------------------------------SDADS-------SCSAPCLSSSCQKLSCCPAG-----PVCVCAPPRDSS-----------------------------------TEKHTPQACTHSSKL-------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20107-1", "uniprot_id": "ZRC1_YEAST", "id": "P20107-1", "name": "Vacuolar zinc transporter ZRC1", "aln": "-----MITGKELRIISLLTLDTVFFLLEITIGYMSHSLALIADSFHMLNDIISLLVALWAVDVAKNRGPDA------------------------------------KYTYGWKRAEILGALINAVFLIALCFSIMIEALQRLIEP---QEIQNPRLVLYVGVAGLISNVVGLFLFHDHGS---DSLHSHSHGSVESGNNDLDIESNATHSHSHASLPN---------------DNLAIDEDAISSPGPSGQIGEVLPQSVVNRLSNESQPLLNHDDHDHSHESKKPGHRSLNMHGVFLHVLGDALGNIGVIAAALFIWKTEYSWR--------------------------------------YYSDPIVSLIITIIIFSSALPLSRRASRILLQATPSTISADQIQREILA-VPGVIAVHDFHVWNLTESIYIASIHVQIDCAP---DKFMSSAKLIRKIFHQHGIHSATVQPEFVSGD-------------------------------------VNEDIRRRFSIIAGGSPSSSQEAFDSHGNTEHGRKKRSPTAYGATTASSNCIVDDA---------------------------VNCNTSNCL--------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "M9PEG6-1", "uniprot_id": "M9PEG6_DROME", "id": "M9PEG6-1", "name": "", "aln": "---MAKYSGKKCRLLSMMWLTAFFFFVEIIVGYVTNSMALVADSFHMLGDIAALVISFLSVKMSPK--KWS------------------------------------KNTFGWARAEVLGALVNAVFLVALCFSITIEACKRFIEE---EPIHEPELLVIVGALGLLVNVIGLCLLYEHGG-----HHGHSHG------------------------------------------------GGLTRNHSRLTELANMDEGEDEQNDFAYEKQKEKAPVKKSSHGHSHDPGQMNMRGAFLHVLSDALGSIIVVISAVVVWKTEWKYR--------------------------------------YYMDPALSIVLVVLILHSVWPLLRESALILLQTVPTHIQVDAIQKRLLEKVDGVLAVHEFHVWQLAGDRIIASAHIRCRNLS----EYMKIAEKVKEFFHNEGIHSTTIQPEFSEIEGCNMSDGTSSINISGSDCCALDCPTTEEGCVKATCCQNNNKLNQLPSPTNSPYLCRQRNAARQAGDVEAGSLLEATSSGNQGATGGASTGAPVAAIGATSTPKSDLVXRQPHQAQQHVHFATTKTETATATTKAATTAAATSIRDIMYEPRANNLVVSSAQVDVNLGLTVTAQRRRELQLQAEQQYQEQVSPLSTRNGDEVAL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPE3-1", "uniprot_id": "Q9VPE3_DROME", "id": "Q9VPE3-1", "name": "", "aln": "MVKDILQRCKPIPLYTVLVLSICYFVLQLILSHLTHGLTLLMASHHMLCNIFALGGCIITIKHSKQAPEARNPSPALTKINGSGVAISLADTDAQTRAKRECREQKLRNTFGWARIDILTMLIVFIILASLSFSLVVEALQTLVHIDHQDTMHLPIPVMMLGFIGLILNGLTYLLIG---------GYTLHQG--------------------------------------------SFLHLTPGGNVVLERPMSSNLDLSLTPMQRHLSKSRNDRQLREELETEVGSVYFATKRQGAVEMLRDVSSTIFVIVCAAIVYVAEDEQHT------------------------------------AKFIDPVLSIFSCVLLVTLSYPYMKESCLILLQTIPGSIDLEIFERTLVTKFPEIISYHDLHIWQLAAHRYVATIHIQFQNPK----LYLKIIEQVRSYFHDQGIGAVTIQPEFYP-----------------------------------------STNKNASASLECLMQCQAVECIEKVCCRDSRTDLREVCDAPSGRKSSSPVKCAG-------NSHEHSRAKSKSCAELSAVVVEKPEELSAGQLLKGQDQQVAKSMPKLEETCVDATKEDTAELSGSPPGPTSSD------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: : ::. :: . : .:::: *.:** :: :* : : : . ::* * ::: * ::* .*.*:: :*: : . :. . :: :* ** * : :: . : :.:: *. ..: *: : .. : ** : :. ::. * :.: **** * : : : . : *: *:*:* :*: *:: . : . ** *: *:* * . . ", "identical_positions": 37, "similar_positions": 93, "identity": "5.41%" }, { "cls_id": "homologset.agr.SGD:S000004857", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LE58-1", "uniprot_id": "A0ABK0LE58_RAT", "id": "A0ABK0LE58-1", "name": "Cytochrome c oxidase assembly factor 6 homolog", "aln": "MAERKVQGASCMANLSFTVTQSQRSLESDLLLNTQRREHGAGSVSSAHSESLLSQSGPPQLRTVFPHGAEGGTNQTLVSVHGPRLRGRKLPAREKDANGSPALPFADGGQDQSIRGGHFRSELPCTVGGPAGRQCSTHSPHRAPTWADPRVARHVAPRVTPAGMAAPSMKERQACWGARDLYWRCLDDN--AEDAAR---------CQKLRSSFEASCPQQWIKYFDKRRDYLKFKEKFEAGEFQSSPSTENS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGD8-1", "uniprot_id": "COA6_MOUSE", "id": "Q8BGD8-1", "name": "Cytochrome c oxidase assembly factor 6 homolog", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAPSMKERQACWGARDLYWRCLDDN--AEDAAR---------CQKLRSSFEASCPQQWIKYFDKRRDYLKFKEKFEAGGFQSSQSTENS-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JTJ3-1", "uniprot_id": "COA6_HUMAN", "id": "Q5JTJ3-1", "name": "Cytochrome c oxidase assembly factor 6 homolog", "aln": "--------------------------------------------------------------------------------MGP---------------GGPLLSPS-------------RGFLLCKTGWHSNRLLGDCGPHTP-------VS--TALSFIAVGMAAPSMKERQVCWGARDEYWKCLDEN--LEDASQ---------CKKLRSSFESSCPQQWIKYFDKRRDYLKFKEKFEAGQFEPSETTAKS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A5J2-1", "uniprot_id": "B8A5J2_DANRE", "id": "B8A5J2-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAPNASQRKACWDARDELWKCLDVN--KDLTSA---------CEKHQREFEANCPAQWVKYFSKRRDFLKYKEKIEKEGYEPTEGASKL-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7Z107-1", "uniprot_id": "B7Z107_DROME", "id": "B7Z107-1", "name": "Cytochrome c oxidase assembly factor 6 homolog", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFPDKAERKKCWNNRDEYWKCLEEH--APKHSSTSGEKVPTPCQSLRKSFEQSCPGQWVKHFDRKRTYDQFKEKMAQG-YDPLEDRTKAEKQAN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3E846-1", "uniprot_id": "COA6_YEAST", "id": "Q3E846-1", "name": "Cytochrome c oxidase assembly factor 6", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MGLFSFDGGKKESQPPNTRSQRKLCWESRDAFFQCLDKADILDAMDPKNSKSIKSHCKVENEKFEENCAHSWIKYFKEKRVIDFKREQTIKRIEQEAKQRERNQ----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*: ** ** ::**: *: . .** .*. .*:*:*..:* :*: : . ", "identical_positions": 16, "similar_positions": 21, "identity": "6.2%" }, { "cls_id": "homologset.agr.SGD:S000004860", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CZW4-1", "uniprot_id": "ACSL3_MOUSE", "id": "Q9CZW4-1", "name": "Fatty acid CoA ligase Acsl3", "aln": "MNNHVSSTPSTMKLKQTINPILLYFIHFIISLYTILTYIPFYFLC----ESKQEKPNQIKAKPV----------------------SSKPDSAYRSIN-SVDGLASVLYPGCDTLDKVFMYAKNKFKNKRLLGTREILNEEDEIQPNGKIFKKVILGHYNWLSYEDVFIRALDFGNGLQMLGQKP--KANIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHGLNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVD----------------GKP--PTWSEFPKGVIVHTMAAVQALGVKANVEKKAHSKPLPSDIAVIMYTSGSTGIPKGVMISHSNIIASITGMAR-RIPRLGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSVLKPTLMAAVPEIMDRIYKNVMNKVNEMSAFQRNLFILAYNYKMEQISKGCSTPLCDRFVFRNVRRLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESTGAGTITEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKTDFFEDENGQRWLCTGDIGEFDPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLIDNICAYANSYHSYVIGFVVPNQKELTELARTKGFKG---TWEELCNSSEMENEVLKVLSEAAISASLEKFEIPLKIRLSPDPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63151-1", "uniprot_id": "ACSL3_RAT", "id": "Q63151-1", "name": "Fatty acid CoA ligase Acsl3", "aln": "MNNHVSSTPSTMKLKQTIHPILLYFIHFIISLYTILTYIPFYFLC----ESKQEKPNHIKAKPV----------------------SSKPDSAYRSVN-SMDGLASVLYPGCDTLDKVFMYAKNKFKDKRLLGTREILNEEDEIQPNGKVFKKVILGHYNWLSYEDVFIRALDFGNGLQMLGQKP--KANIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHGLNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVD----------------GKP--PTWSEFPKGVIVHTMAAVQALGVKADVDKKAHSKPLPSDIAVIMYTSGSTGIPKGVMISHSNIIASITGMAR-RIPRLGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSVLKPTLMAAVPEIMDRIYKNVMNKVNEMSAFQRNLFILAYNYKMEQISKGCSTPLCDRFVFRNVRRLLGGNIRVLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESTGAGTITEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFDPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLIDNICAYANSYHSYVIGFVVPNQKELTELARTKGFNG---TWEELCNSSEMENEVLKVLSEAAISASLEKFEIPLKIRLSPDPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95573-1", "uniprot_id": "ACSL3_HUMAN", "id": "O95573-1", "name": "Fatty acid CoA ligase Acsl3", "aln": "MNNHVSSKPSTMKLKHTINPILLYFIHFLISLYTILTYIPFYFFS----ESRQEKSNRIKAKPV----------------------NSKPDSAYRSVN-SLDGLASVLYPGCDTLDKVFTYAKNKFKNKRLLGTREVLNEEDEVQPNGKIFKKVILGQYNWLSYEDVFVRAFNFGNGLQMLGQKP--KTNIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVD----------------GKP--PTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNIIAGITGMAE-RIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQISKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKG---TWEELCNSCEMENEVLKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TXZ5-1", "uniprot_id": "A0AB32TXZ5_DANRE", "id": "A0AB32TXZ5-1", "name": "long-chain-fatty-acid--CoA ligase", "aln": "-----------MKLKEDMSPLLLQVFRSVVWVYSVITFLPWYLLSGASGN--QARAKRVKARAI----------------------NGNPAGPYRAVN-SQLKLASLLHEGVDTLDKVFEYAVVHFPERDCLGTRELLSEEDEIQPNGKVFKKVILGDYNWLSYQDTFHLAQRFGSGLAALGQKP--LCNIAIFCETRAEWVIAAQACFMYNFPLVTLYSTLGGSAIAHGLNETEVTHIVTSKDLLQSRLKAILLEVPRLKHIIVVD----------------TKP--TSWPDLPRGIMVHNMAAVQELGSKPENIMVSRRQPVPSDIAVIMYTSGSTGIPKGVMISHSNIIAGITGMAE-RIPNLDENDTYIGYLPLAHVLELSAELVCVSHGCRIGYSSPQTLADQSSKIKKGSKGDTSVLKPTLMAAVPEIMDRIYKNVMTKVEEMSSVQKTLFVLAYNYKMEQISKGYTTPLCDRLVFRKVRSLLGGNTRVLLSGGAPLSAATQRFMNICFCCPVGQGYGLTETCGAGTISEMSDYSTGRVGAPLVCSEIMLKDWEEGGYFGTDKPNPRGEILIGGPNVTMGYYKNEQKNREDFFEDKNGQRWFCTGDIGEFHPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAVLKNCPLIDNICAYANSDESYVIGFVVPNQKQLTALAGQKGIRG---SWEEICNHAEMEKEVLRIITDAAISGKLERFEIPKKICLSAEPWTPETGLVTDAFKLKRKELKTHYQDDIERMYGGK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1LVA8-1", "uniprot_id": "Q1LVA8_DANRE", "id": "Q1LVA8-1", "name": "long-chain-fatty-acid--CoA ligase", "aln": "-----------MRLTQDLSPAVVLVFRLVVWLYSLISYLPYLLLRSPESQSLSECSRRLKARSV----------------------SGDPAGPYRDVA-ALKGLEMCLHPGINTLDQVFQSSVSHFPNSDCLGTRELLSEEDETQEDGKVFKKVILGEYRWMSYEQVFKEVNAFGSGLAALGQKP--MKNIAIFCETRAEWIIAAQACFMYNFPLVTLYSTLGGPAIAHGLNEAEVSHIITSKDLLETKLKSIFIEVPRLCHVIVVD----------------DKL--STSSEYPRGISIHSMASVKELGARPENASKPKNPPCSSDVAVIMYTSGSTGVPKGVMISHSNIISGITGMTH-RIPKLVEDDTYIGYLPLAHVLELSAEMVCLAHGCRIGYSSPQTLSDQSTKIKKGSRGDISVLRPTLMAAVPEIMDRIYKNVMLRVEQMSGFQRTLFLLAYNYKMEQLAMGYSTPLCDKLVFRKVRALLGGRLRVLLSGGAPLSAATQRFMNICFCCPVGQGYGLTETCGAGTISHLWDYSTGRVGAPLVCCELQLKDWIEGGYHSTDLPCPRGEILVGGPSITMGYYKNTHKTSEDFFVDKKGQRWFCTGDIGEIHGDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLVDNICAYANSDESYVIGFVVPNQKQLLALAERKRVRG---LWEELCNNPVIEEAVLTVLTEAALTAQLERFEIPRKIRLSVEPWTPDTGLVTDSFKLKRKELKTHYQNDIERMYGAK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9QUJ7-1", "uniprot_id": "ACSL4_MOUSE", "id": "Q9QUJ7-1", "name": "Long-chain-fatty-acid--CoA ligase 4", "aln": "-----------MNLKLNVLTIILLPVHLLITIYSALIFIPWYFLTN--AKKKNAMAKRIKAKPT----------------------SDKPGSPYRSVT-HFDSLAVIDIPGADTLDKLFDHAVAKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWINYLEVNCRVNNFGSGLTALGLKP--KNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGREAVVHGLNESEASYLITSVELLESKLKAALVDINCVKHIIYVD----------------NKT--INRAEYPEGLEIHSMQSVEELGAKPENLSVPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCE-RIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYVQKTLFKIGYDYKLEQIKKGYDAPLCNLILFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTVHDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYCVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKKLTLLAQQKGVEG---SWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELKNHYLKDIERMYGGK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35547-1", "uniprot_id": "ACSL4_RAT", "id": "O35547-1", "name": "Long-chain-fatty-acid--CoA ligase 4", "aln": "-----------MKLKLNVLTIVLLPVHLLITIYSALIFIPWYFLTN--AKKKNAMAKRIKAKPT----------------------SDKPGSPYRSVT-HFDSLAVIDIPGADTLDKLFDHAVAKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWINYLEVNCRVNNFGSGLTALGLKP--KNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKAALLDINCVKHIIYVD----------------NKT--INRAEYPEGLEIHSMQSVEELGSKPENSSIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCE-RIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAPLCNLILFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTVHDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKKLTLLAQQKGVEG---SWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELKNHYLKDIERMYGGK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60488-1", "uniprot_id": "ACSL4_HUMAN", "id": "O60488-1", "name": "Long-chain-fatty-acid--CoA ligase 4", "aln": "-----------MKLKLNVLTIILLPVHLLITIYSALIFIPWYFLTN--AKKKNAMAKRIKAKPT----------------------SDKPGSPYRSVT-HFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKP--KNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVD----------------NKA--INKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCE-RIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEG---TWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKDIERMYGGK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KFE4-1", "uniprot_id": "A0A0B4KFE4_DROME", "id": "A0A0B4KFE4-1", "name": "long-chain-fatty-acid--CoA ligase", "aln": "-------------MDSFWVQSAIGAIKAIAFVYDIITLPVYLVLQKP--WKRRQDSRRVKAKPINQKMLVDESKYAPDDIEAKIVRNDDNELTYRTTDPPRDVHVKMLQENIDTLEKVFNYVAKTYTSKRCLGTRQILSEEDEVQQNGRVFKKYNLGDYKWKTFTEAERTAANFGRGLRELGQKP--RENIVIFAETRAEWMIAAHGCFKQAMPIVTVYATLGDDGVAHCITETEVTTVITSHDLLP-KFKTLLDKCPLVKTIIYIE----------------DQLQKTETTGFKEGVKILPFNQVVKTGQDSKFEHVP---PKGDDIAIIMYTSGSTGTPKGVLLSHKNCIATMKGFVD-MVP-IYPDDVLIGFLPLAHVFELVAESVCLMTGVPIGYSTPLTLIDTSSKIKRGCKGDATVLKPTCMTSVPLILDRISKGINDKVNSGSAFKKSLFKFLYQYKVKWVQRGYKTPLIDKLVFKKVAKLMGGKVRIIMSGGAPLSADTHEQIKTCLCLELIQGYGLTETTSGATVMDYRDMTYGRTGGPLTVCDIRLVNWEEGNYRVTNKPYPQGEVLIGGECVSQGYYKLPGKTNEDFFE-EDGQRWFKTGDIGEIQADGVLKIIDRKKDLVKLQAGEYVSLGKVESELKTCGIIENICVYGDPTKQYTVALVVPNQNHLEELAQKHGLGDK--SFEELCSSPIIEKAILKEIAEHARKCKLQKYEVPAAITLCKEVWSPDMGLVTAAFKLKRKDIQDRYQHDINRMYAS--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47912-1", "uniprot_id": "LCF4_YEAST", "id": "P47912-1", "name": "Long-chain-fatty-acid--CoA ligase 4", "aln": "-----------------------------------MTEQYSVAVGEAANEHETAPRRNIRVKDQ---------------------------PLIRPINSSASTLYEFALECFTKGGKRDGMAWRDIIDIHETKKTIVKRVDGKDKPIEKTWLYYELTPYITMTYEEMICVMHDIGRGLIKIGVKPNGENKFHIFASTSHKWMKTFLGCMSQGIPVVTAYDTLGESGLIHSMVETDSVAIFTDNQLLS-KLAVPLKTAKNVKFVIHNEPIDPSDKRQNGKLYKAAKDAVDKIKEVRPDIKIYSFDEIIEIG-KKAKDEVELHFPKPEDPACIMYTSGSTGTPKGVVLTHYNIVAGIGGVGHNVIGWIGPTDRIIAFLPLAHIFELTFEFEAFYWNGILGYANVKTLTPTSTRN---CQGDLMEFKPTVMVGVAAVWETVRKGILAKINELPGWSQTLFWTVYALKERNIP---CSGLLSGLIFKRIREATGGNLRFILNGGSAISIDAQKFLSN-LLCPMLIGYGLTEGVANACVLEPEHFDYGIAGDLVGTITAKLVDVEDLGYFAKNN---QGELLFKGAPICSEYYKNPEETAAAFTD----DGWFRTGDIAEWTPKGQVKIIDRKKNLVKTLNGEYIALEKLESIYRSNPYVQNICVYADENKVKPVGIVVPNLGHLSKLAIELGIMVPGEDVESYIHEKKLQDAVCKDMLSTAKSQGLNGIELLCGIVFFEEEWTPENGLVTSAQKLKRRDILAAVKPDVERVYKENT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ..::.: * . : . . : :.: : : : * * .: : :* ** :* ** .: **..* :*: : *: : :** * *** .: * : *:: :.*. :** :: . : :* : : .. : : : * * .* * :******** ****:: * * :: : * : : * *.:*****::** * .. . :**:. ** *:: .:** ::** *..*. : : : *.: ::.. .:.** * * . : : * . ::*:.: **. *.:: **:.:* ::. :. : : ****** . . : . . * .* : * : : .* : :**::. * : *:* :. : : *: ****.* .* ::******:*** ***::* *:*: :. ::***.:.. . :.:**** .* ** . . :: : : . * *: *: : : : *:*: **** : ****::: *::*:* ", "identical_positions": 142, "similar_positions": 183, "identity": "18.39%" }, { "cls_id": "homologset.agr.SGD:S000004861", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M9Q3-1", "uniprot_id": "F1M9Q3_RAT", "id": "F1M9Q3-1", "name": "E3 ubiquitin-protein ligase listerin", "aln": "MSPLPARGTGSCGPAVSTSPLQTETPAATATMGGKNKQ--RTKGNLRPSNSGRAAELLAKEQGTVPGFIGFGTSHSDLGYVP----AIQGAEDIDSLVDSDFRMVLRKLSKKDVTTKLKAMQEFGTMCTERDTEAVKG---VLPYWPRIFCKISLDHDRRVREATQQAFEKLILKVKKHLAPYLKSVMGYWLMAQCDTYPPAATAAKDAFEAAFP--PSKQPEAIVFCKEEITTVLQDHLLKETPDTLSDPQTVPEEEREAKFHRVVTCSLLALKRLLCFLPN-NELDSLEEKFRSLLSQNKFWKYGKHSVPQVRSAYFELVSALCQHVP-------QVMKEEAAKVSPSVLLSIDDSDPVVCPALWEAVLYTLTTVEDCWFH--VNAKKSVFPKLTAMIRDGGRGLAAVIYPYLLPFISKLPQS--ITEPKLDFFKNFLTSLVTGLSTERTRSSS-AECSAVIAAFFECLRFIMQQN-------LGEEEMVQMLIGEQLIPFIDIVLKDSGLQHGPLFNHLADTLSSWEAKADVEQDAETVYNLEKVLLSFWERLSEICIEKISEPEADVKSVLGVSNLVGILQKPESSLKSNRKRNGKVRFVIDTPEAPKGSEKCVSSEGENSEGSEGGGTGSSLSYKSSDVVSPLRKKPLEDLVCKLAEVSISFVNEQKSEQHLQFLSTLLDSFSSGQVFKILLGDKQKNIVKAKPLEITKLAEKNPAVQFLYHKLIGWLNDSQKEDGGFLVDILYSALRCCDSDVERKEVLDDLTQEDLKWSSLLRVIEKACSSSDKHALVTPWLKGSILGEKLVALADCLCGKDLESTISSECHSSEQWTLLRLALSQHLKNDYLIGEVYVARIIVKLHETLSKTKDFSEAADSDSSVSFVCDVIHSFFSSAGGGLLTPASEDLLLTLFQLCAQSKERTHLPDFLICKLKNTLLSGVNLLVHQTASTYEQSTFLRLSVLWLKDQVQSSVLD---NESLQVLLSAVGDLLSTLVESE--DTSLLGVYIGSVMPSDSEWEKMRQSLPVQWLHRPLLEGRLSLNYECFKTDFKDQDTKTLPNHLCTSSLLSKMILIAQKKE---------IVLENDVLEKICAELLYSLQWCEELDNPPSFLSGFCEMLQK-----MNITYSNLSVLGNTSSLLQLLFDRSRKNGTLWSLIIAKLILSRS-------ISSDEVKPYYKRKESFFPLTEGNLHTIQSLCPFLSKEEKKEFSAQCIPAFLGWTKEDLCSINGAFGHLAIFNSCLQTRSIDDKQLLHGILKIITSWR---KQHEDIFLFSCNLSEASPEVLGLNIEIMRFLSLFLKYCSY--PLAESEWDFIMCSMLAWLETASENQALYCVPLVQLFACVSFDLACDLSAFFDSITPDTVDNLPVNLISEWKEFFSKGIHGLLLPLLVNATGEDKDLSETSFQNAVLKPMCETLTYISKDQLLSHKLPKRLVASQKTNLPEHLQTLLNTLTPLLLFRARPVQIAAYHMLYKLMAELPQHDQDNLKSYGDEEEEPALSPPAALMS----LLSTQEELLENVLGCVPVGQIVPIKPLSEDFCYVLGYLLTWKLILTFFKAASSQLRALYSMYLRKTKSLNKLLYHLFRLMPENPTYGETAIEVSNKDPKTFFTEELQLSIRETATLPYHIPHLACSVYHMTLKDLPAMVRLWWNSSEKRVFNIVDRFTSKYVSSVLSFQEISSVQTSTQLFNG----MTVKARATTREVMATYTIEDIVIELIIQLPSNYPLGSITVESGKRVGVAVQQWRNWMLQLSTYLTHQNGSIMDGLALWKNNVDKRFEGVEDCMICFSVIHGFNYSLPKKACRTCKKKFHSACLYKWFTSSNKSTCPLCRETFF---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6A009-1", "uniprot_id": "LTN1_MOUSE", "id": "Q6A009-1", "name": "E3 ubiquitin-protein ligase listerin", "aln": "-------------------------------MGGKNKQ--RTKGNLRPSNSGRAAELLAKEQGTVPGFIGFGTSHSDLGYVP----AVQGAEDIDSLVDSDFRMVLRKLSKKDVTTKLKAMQEFGIMCTERDTEAVKG---VLPYWPRIFCKISLDHDRRVREATQQAFEKLILKVKKHLAPYLKSVMGYWLMAQCDTYPPAALAAKDAFEAAFP--PSKQPEAIAFCKEEITTVLQDHLLKETPDTLSDPQTVPEEEREAKFHRVVTCSLLALKRLLCFLPN-NELDSLEEKFKSLLSQNKFWKYGKHSVPQVRSAYFELVSALCQHVP-------QVMKEEAAKVSPSVLLSIDDSDPVVCPALWEAVLYTLTTIEDCWFH--VNAKKSVFPKLMAMIREGGRGLAAVMYPYLLPFISKLPQS--ITEPKLDFFKNFLTSLVTGLSTERTKSSS-SECSAVISAFFECLRFIMQQN-------LGEEEMVQMLINEQLIPFIDTVLKDSGLHHGPMFDHLADTLSSWEAKADAERDPGAVYNLENVLLSFWGRLSEICTEKIRQPEADVKSVLCVSSLVGVLQRPRSSLKLHRKKTAQVRFAINIPEAHKGDEKSMSSEGENSEGSDGG-AQSPLSNTSSDLVSPLRKKPLEDLVCKLAEVSISFVNERKSEQHLQFLSTLLDSFSSVQVFNILLSDKQKNVVKAKPLEITKLAEKNPAVKFLYHKLIGWLNDSQKEDGGFLVDILYSALRCCDSGVERKEVLDDLTKEDLKWSSLLQVIEKACSSSDKHALVTPWLKGSILGEKLVALADCLCDKDLEATTS-ESHSSEQWSLLRLALSQHVKNDYLIGEVYVGRIIVKLHETLSKTKDLSEAANSDSSVSFVCDVVHSFFSSAGGGLLMPPSEDLLLTLFQLCAQSKERTHLPDFLICKLKNTLLSGVNLLVHQTASTYEQSTFLRLSVLWLKDQVQSSALD---NTSLQVLLSAAGDLLGTLVESE--DTSLLGVYIGSVMPSDSEWEKMRQALPVQWLHRPLLEGRLSLNYECFKTDFKEQDTKTLPNHLCTSSLLSKMILVAQKKK---------LVLEDNVLEKIIAELLYSLQWCEELDNAPSFLSGFCGILQK-----MNITYSNLSVLSETSSLLQLLFDRSRKNGTLWSLIIAKLILSRS-------ISSDEVKPYYKRKESFFPLTEGSLHTIQSLCPFLSKEEKKEFSAQCIPAFLGWTKEDLCSINGAFGHLAIFNSCLQTRSIDDKQLLHGILKIITSWR---KQHEDIFLFSCNLSEASPEVLGLNIEIMRFLSLFLKHCAYPLPLADSEWDFIMCSMLAWLETTSENQALYSVPLVQLFACVSFDLACDLCAFFDSITPDIVDNLPVNLISEWKEFFSKGIHSLLLPLLVNAIGENKDLSETSFQNAMLKPMCETLTYISKDQLLSHKLPARLVASQKTNLPEHLQTLLNTLTPLLLFRARPVQIAAYHMLCKLMPELPQHDQDNLRSYGDEEEEPALSPPAALMS----LLSSQEELLENVLGCVPVGQIVTVKPLSEDFCYVLGYLLTWKLILTFFKAASSQLRALYSMYLRKTKSLNKLLYHLFRLMPENPTYGETAIEVSSKDPKTFFTEEVQLSIRETATLPYHIPHLACSVYHMTLKDLPAMVRLWWNSSEKRVFNIVDRFTSKYVSNVLSFQEISSVQTSTQLFNG----MTVKARATTREVMATYTIEDIVIELIIQLPSNYPLGSITVESGKRIGVAVQQWRNWMLQLSTYLTHQNGSIMEGLALWKNNVDKRFEGVEDCMICFSVIHGFNYSLPKKACRTCKKKFHSACLYKWFTSSNKSTCPLCRETFF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94822-1", "uniprot_id": "LTN1_HUMAN", "id": "O94822-1", "name": "E3 ubiquitin-protein ligase listerin", "aln": "-------------------------------MGGKNKQ--RTKGNLRPSNSGRAAELLAKEQGTVPGFIGFGTSQSDLGYVP----AIQGAEEIDSLVDSDFRMVLRKLSKKDVTTKLKAMQEFGTMCTERDTETVKG---VLPYWPRIFCKISLDHDRRVREATQQAFEKLILKVKKQLAPYLKSLMGYWLMAQCDTYTPAAFAAKDAFEAAFP--PSKQPEAIAFCKDEITSVLQDHLIKETPDTLSDPQTVPEEEREAKFYRVVTCSLLALKRLLCLLPD-NELDSLEEKFKSLLSQNKFWKYGKHSVPQIRSAYFELVSALCQRIP-------QLMKEEASKVSPSVLLSIDDSDPIVCPALWEAVLYTLTTIEDCWLH--VNAKKSVFPKLSTVIREGGRGLATVIYPYLLPFISKLPQS--ITNPKLDFFKNFLTSLVAGLSTERTKTSS-LESSAVISAFFECLRFIMQQN-------LGEEEIEQMLVNDQLIPFIDAVLKDPGLQHGQLFNHLAETLSSWEAKADTEKDEKTAHNLENVLIHFWERLSEICVAKISEPEADVESVLGVSNLLQVLQKPKSSLKSSKKKNGKVRFADEILESNKENEKCVSSEGEKIEGWELT-TEPSLTHNSSGLLSPLRKKPLEDLVCKLADISINYVNERKSEQHLRFLSTLLDSFSSSRVFKMLLGDEKQSIVQAKPLEIAKLVQKNPAVQFLYQKLIGWLNEDQRKDFGFLVDILYSALRCCDNDMERKKVLDDLTKVDLKWNSLLKIIEKACPSSDKHALVTPWLKGDILGEKLVNLADCLCNEDLESRVSSESHFSERWTLLSLVLSQHVKNDYLIGDVYVERIIVRLHETLFKTKKLSEAESSDSSVSFICDVAYNYFSSAKGCLLMPSSEDLLLTLFQLCAQSKEKTHLPDFLICKLKNTWLSGVNLLVHQTDSSYKESTFLHLSALWLKNQVQASSLD---INSLQVLLSAVDDLLNTLLESE--DSYLMGVYIGSVMPNDSEWEKMRQSLPMQWLHRPLLEGRLSLNYECFKTDFKEQDIKTLPSHLCTSALLSKMVLIALRKE---------TVLENNELEKIIAELLYSLQWCEELDNPPIFLIGFCEILQK-----MNITYDNLRVLGNTSGLLQLLFNRSREHGTLWSLIIAKLILSRS-------ISSDEVKPHYKRKESFFPLTEGNLHTIQSLCPFLSKEEKKEFSAQCIPALLGWTKKDLCSTNGGFGHLAIFNSCLQTKSIDDGELLHGILKIIISWK---KEHEDIFLFSCNLSEASPEVLGVNIEIIRFLSLFLKYCSS--PLAESEWDFIMCSMLAWLETTSENQALYSIPLVQLFACVSCDLACDLSAFFDSTTLDTIGNLPVNLISEWKEFFSQGIHSLLLPILVTVTGENKDVSETSFQNAMLKPMCETLTYISKEQLLSHKLPARLVADQKTNLPEYLQTLLNTLAPLLLFRARPVQIAVYHMLYKLMPELPQYDQDNLKSYGDEEEEPALSPPAALMS----LLSIQEDLLENVLGCIPVGQIVTIKPLSEDFCYVLGYLLTWKLILTFFKAASSQLRALYSMYLRKTKSLNKLLYHLFRLMPENPTYAETAVEVPNKDPKTFFTEELQLSIRETTMLPYHIPHLACSVYHMTLKDLPAMVRLWWNSSEKRVFNIVDRFTSKYVSSVLSFQEISSVQTSTQLFNG----MTVKARATTREVMATYTIEDIVIELIIQLPSNYPLGSIIVESGKRVGVAVQQWRNWMLQLSTYLTHQNGSIMEGLALWKNNVDKRFEGVEDCMICFSVIHGFNYSLPKKACRTCKKKFHSACLYKWFTSSNKSTCPLCRETFF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VW09-1", "uniprot_id": "LTN1_DROME", "id": "Q9VW09-1", "name": "E3 ubiquitin-protein ligase listerin", "aln": "-------------------------------MGGKTKQAPRTKNNAKPSSSSRTAELLGSSTPIFVGFSAQTDGGGLVPFAPGFASAEQMPDSFDAAISPQTQIILRKLSKKDPMTKKKALQELHELIEQSDVEVLKN---ILPLWPKYYLNLASDPEHTVREQTQTVLQLLMAKCKKAMAPYLKLLVPVWLGSRFDTYAPAASIASQSFRDTFAGNANRSREVCMHCQVEILEYATRNLTFHTAATLSIGKSLTPEDAEQKYQRVIISSLKLLSFFMGQTAQTEELSQVKEGFGTLVAHQKFWSFAKHKVPAIKAAWFECIYHILQSVAL-----LDVITPQKTQLTNLCFQFIDDADPVVAPHIWGCVLLLQSNYVDWFVP--LNIRKTLLPKLSSLLQNGFNRNAQAICPNLLPFLSKVTQASLQDLDIYDFYQRFFDDMKLAVTKKFDPPLSKSDCIVIHNAYFECLRFLMQQINNNKQREQKEEEFSFSLLDNNVLEPIAWLLKSDSTHVKIFFQHSSALVAFWDRQINNRLDNGDLY--AKLLNKFWIRIFELVTQDLSAEEVNEQLLGHVLLLVQDLHMANPSLESP-------------------SVKFVEGPNEKIEKSEPTTPVKKAQEAAAFIQKELKQLVIKLVRICLDKANKGSGSGTSSSRYIEQIRTLTKMFNDAAFYKSLTDDGD--------------------LASALNKFVSLLGQLSCQACESVVEIVFEILPLLETGKRFEYIENTLMKLPQHGVQNLLLHRLLSYPLCAEAAVRQMLSGPETCEMIARIAEEVVVD----------NDREKLNLLHKCFFQTDTGDILINAKTVDKILLSMCGPLEQPVVDDAVEVCGSFIAQIMPVICSNNNSS-----LHVRQHIFLKLFKFSLEHRPEDYLSEDTLWEITTCWQDGLSSKDIEIDDDMLKCCAGIVEELANSAELKADTLDGMAEAMAKFVICSTENIEDEYKRLERIDETLTALLETPLKTTDKVQQFENHCVLLEALHGSVTAGVPFENACLSRNEILPLLQRSTLNFSTIYKLVYQFPPPQDTNDPEDELTEDYCDPNADVLKKWNEPLIAELLQCIRVAGTAECWLEMSVLQSSTEELVLILSEKVQSFMGNSSDLVAIVKERLQQAAVQQSSVIDCRLLSYLRFCPQYAAFEESASILLHEDLSENLVTQGALKTYVIALQFLLP-KLSQKAITLSSAIMGTEPPEIWVKAAVFHALLLNNFEGDVNEQTDRNIIVSAVQFMTSIGERQASQKDLLHYNVEIQRQPYESVINTVEFIKLLTEVLKRFPY--ELSIKNWDAIRIGLSSWVLSVSKSIAQYQDPKTSLFIVAVYELFAALIDFIRSEKQKSSTELLKNMIDEWDSLFAKEVN---LVLFKSYYLLTHEVSVDPGFQACYEALLEQITPVIER--LDYSFVYSFCKSNSN---ITLDHLCNFLFKQLYSVQHSVRLSAVHSLRQLTPHFVADDIELNEKQSESLDASTTICKWHFLNRFEDYLTRYDALITKYLEEFTFKLSELDDLEPIDRHNALSYLFLWDCIINACAKSPVALRAVYTNWLNDNKYEENFLHFLFRAMPVDILKNHGAKVHSNG-----VYKELTWSQQKDRHLP--LERYACHLYTEVLRKLPAVVRRWWNATQSRQKNFIDNLTTNYVSSLICSEELKAIANRKEKHEN----MQVTVHSSTREVLAVYAIDEARMELVITLAPNYPLGAVKVECGKQIGGRASSR-NVGMQLTIFLTHQNGTIYDGLTMWKNNLDKKFEGVEECYVCYTVIHQETCQLPKLTCKTCKKKFHGPCLYKWFTTSSKSTCPICRNVF----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04781-1", "uniprot_id": "LTN1_YEAST", "id": "Q04781-1", "name": "E3 ubiquitin-protein ligase listerin", "aln": "------------------------------------------------MSFGGINTFQQYNTDLGLGHNGVRISLNYFDGLP-------DPSLLNSLYSNELKLIFKSLLKRDETTKEKALMDLSNLISDFNQNEYFFNDIFLLCWSQIYAKLIISDYKVIRLQSHQITIMLVKSLRKKISKFLKDFIPLILLGTCELDYSVSKPSLNELTECFNKDPAKINALWAVFQEQLLNLVKEIVVNENEDTISDERYSSKEESEFRYHRVIASAVLLLIKLFVHNKDVSERN--SSSLKVILSDESIWKLLNLKNGQNTNAYETVLRLIDVLYTRGYMPSHKNIMKLAVKKLLKSLTHITSKNILKVCPVLPSILNLLATLDDYEDGTIWSYDKSSKEKVLKFLSVSRTSPSPGFFNAVFALYSSTKRH-----SFLDYYLEWLPFWQKSVQRLNEKGFSARNSAEVLNEFWTNFLKFAEDS---------SEERVKKMVESEIFNSLSCGKSLSEYTKLNQTLSGVFPPDKWEREIEDYFTS--DEDIRKIKVSFEKNLFALLVTSPNNESAISRLFDFFVQLIETDPS---------------------------NVFNKYDGVYDALNYFLDSDMIFLNGKIGKFINEIPTLVQESTYQNFAGIMAQYSNSKFFKMNTDAITSLEDFFIVALSFNLPK------------------------------------------------TIILATMNELDNDIYQQLMKSDSLELELYIEDFMKNYKFDDSGEIFKGNNKFLNQRTITTLYRSAVAN---------------GQVEQFCAVLSKLDETFFSTLLLNTDFLSCALYEVSEDTNEKLFKLSLQLAKG-------------------------------------NSEIANKLAQVILQHAQVYFSPGAKEKYVTHAVELINGCNDTSQIFFPANAIEVFARYMPAIDYRSSLVSSLSTNTHLLLTDD------------KPINLKNMQKLIRYALFLDALLDALPER-VNNHIVAFITVVSELVTDYNCLSEEPNDLYYDFGHTFFKHG------------------KVNLNFSDIVGNVIQPANGGDAMLTFDIAESN-----------SVYFFYYSRVLYKVLLN---SIDTVSSTTLNGLLASVES-------FVTKTVRDQKSTDKDYLLCAILLLMFNRSN---SKDEITKLRTLLASQLIGIR--EVELVDQEFKSLALLNNLLDIPQADKQFVPIAPQRLNMIFR-------SILKWLDSDLAYEPSFSTVRLLLLDFFTKLMRFEGVR-DMGITAFELSERLLADSLSMCQIDDTLY-----------LLELRSSCLNLYETLSQG------VSKNGEEISEYGDEIQENLIELMFLNFNQERNNQVSTLFYQKLYKVISSMELKKLESQYKRIFEVVLNDKDIGSNINQSRLLTTLLGSLVVKTQQDIIIEYELRIQKQTGSDVDGSASDNDVNS--------------------KFKLPQKLLQKVTDEVPKEYLEYEN-----KNSFIKYLWYWHLILMYFKDTSYNMRQIFIEQLKEAGLINRMFDFITDQIDLR--DTEFWKQVDTKEISEYNIVGNNFSPYKEDIFEECKKLLGHTLYQLFNNVGCLTSIWWLNIKDRTLQNDIEKFVSEFISPILIKNEFDDINSKMDRLTSNDDALTIKLNNITNEVKASYLIDDQKLEISFKLPKNYPLTNIQVNGVSRVGISEQKWKQWIMSTQHVITGMNGSVLDSLELFTKNVHLQFSGFEECAICYSILHAVDRKLPSKTCPTCKNKFHGACLYKWFRSSGNNTCPLCRSEIPFRR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . *. . . . . * .. ::: . : :::::.* *:* ** **: :: : : : : .* *.: : :: . : :* :: *: . :* :: :** .: * . : ..: : : : * . : : :: : .. *:* : . *: * :: **: .:: * :: : .* . .. : :::.:.:*. : . *: : : . . : : : * . : : : .:* :. * . *: *: .: . : : ::.: *. : *:: .:: .: * :. : :: : : :: .** :: .::: : . *: : : :: * .: : . .. . . . *: . . . . . . : : : . . : :* . * :: *: : :.. : : . : . : . .. . :*: *: : : : . *:. : : : : . . : . *.: : . * . : . : :: . ::.: : .. : . .: :: * .: : . . * .: : * : : . . : .. .: : * :: : . . * : : * .. : . : * : .: . ::* :: * * : * : . . : . :: .:: : . . : :: ::: .:: :. . :: : : . . : * :* . : : . . .* . :.. :: : :: :: . . : . : . : : .: * . * : : : : : : . . . :. : *: : .. . : ** *. *: :. :* :: *.. :.:: .: : . . * : : . :* . * * .: * ::.:.::::* :: :*:. : . : . : :. . *.** * * *:: :*: : *. **** : *: .::* .. : :. :* **:: :.* ::.:*:. :*.*.*:* :*::::* .**. :* ***:***..****** :*.:.***:**. : ", "identical_positions": 125, "similar_positions": 450, "identity": "6.68%" }, { "cls_id": "homologset.agr.SGD:S000004866", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BY79-1", "uniprot_id": "S35G1_MOUSE", "id": "Q8BY79-1", "name": "Solute carrier family 35 member G1", "aln": "MGPPESAAELAAEAVELREPELQLADPASPG--EEHVDVEAEGAPGRGRCWPCGAWACGSRGEPEAKKKAPCPGLGLFYTVLSAFLFSVASLFVKKVQG----------VHAVEISAFRCVVQMLVIIPCLIYRK----TGFIGPKGQRLFLFLRGVFGSSAMILMYYAFQTTSLADATVIAFSCPVFTSIFAWIFLKEKYSLWDAFFTLFAIAGVILIVRPPFIFG------SDTSGMRES-YSEHIKGTFAAIGHAVLAAITLVILRKMGKSVDYFLSIWYYVILGLPEAIIILFVIG--EWSLPYCGLDRLFLILIGLLGLGGQIFITKAVQIEKAGLVAIMKTMDIVFAFIFQIAFFDNVPTWWTVGGALCVVVSTTGATIRRWLQGSK---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LVD2-1", "uniprot_id": "A0ABK0LVD2_RAT", "id": "A0ABK0LVD2-1", "name": "Solute carrier family 35 member G1", "aln": "MGPPESAAELSPEAVELREPELQLADPASPG--EEHVDVEAEGAPGRGRCWPCRAWACGSRGEPEAKKTAPCPGLGLFYTVLSAFLFSVVSLLVKKVQG----------VHAVEISAFRCVVQMLVIIPCLIYRK----TGFIGPKGQRLFLFLRGVFGSSAMILMYYAFQTTSLADATVIAFSCPVFTSIFAWIFLKEKYSLWDAFFTLFAIAGVILIVRPTFLFG------SNTSGMRES-YSEHIKGTFAAIGHAVLAAMTLVILRKMGKSVDYFLSIWYYVILGLPETIVVLFVIG--EWSLPYCGRDRLFLILIGLVGLGAQIFITKALQIEKAGLVAIMKTMDVVFAFIFQIAFFDNVPTWWTVGGALCVVVSTTGATIRRWLQSK----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2M3R5-1", "uniprot_id": "S35G1_HUMAN", "id": "Q2M3R5-1", "name": "Solute carrier family 35 member G1", "aln": "MRPQD-----STGVAELQEPGLPLTDDAPPGATEEPAAAEAAGAPDRGRCWLCLSSPCCSRTEPEAKKKAPCPGLGLFYTLLSAFLFSVGSLFVKKVQD----------VHAVEISAFRCVFQMLVVIPCLIYRK----TGFIGPKGQRIFLILRGVLGSTAMMLIYYAYQTMSLADATVITFSSPVFTSIFAWICLKEKYSPWDALFTVFTITGVILIVRPPFLFG------SDTSGMEES-YSGHLKGTFAAIGSAVFAASTLVILRKMGKSVDYFLSIWYYVVLGLVESVIILSVLG--EWSLPYCGLDRLFLIFIGLFGLGGQIFITKALQIEKAGPVAIMKTMDVVFAFIFQIIFFNNVPTWWTVGGALCVVASNVGAAIRKWYQSSK---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGN6-1", "uniprot_id": "Q9VGN6_DROME", "id": "Q9VGN6-1", "name": "EamA domain-containing protein", "aln": "----------MPENLELQQ------------------FQEGAPPPDPAPRWLER---------LQRRLGADCPYLGILLATLSSLFFSLCSVIVKGLVD----------VNPMELASFRFVGVLLPALPILIYTR----QPVF-PEGKRVILLLRCFMGTTGLMLSFYAFRHMPLADASVIIFSTPVFVAIFARAFLKEPCTLFNVLTINMTLLGVVLITRPPFVFG------DTAESEDVAGKTYDIWGPVAAISSTLFGANVYILLRAL-KNLHFSVIMTNFGTIALVYTLIVCASIG--AVCWPSCGRDRWLVVVLGVFSFLGQILLTLSLQIEQAGPVAIARCADIVFAFVWQMLFFGETPTAYSLVGAVMVMGSVVLTALKKWAGTLPRESSLR-----KRFRLILLE-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04835-1", "uniprot_id": "YM87_YEAST", "id": "Q04835-1", "name": "Uncharacterized membrane protein YMR253C", "aln": "------MNPSVPKVMKRENNTHLLVSKEMNDTSLQLPSTTRSLSPKESNSNEDFNVDGNETTLQRISKDYLKPNIGLVLLTVSYFFNSAMVVSTKVLENDPDDIANDRQIKPLQILLVRMVITYIGTLIYMYINKSTISDVPFGKPEVRKWLVLRGCTGFFGVFGMYYSLMYLTISDAVLITFLAPSLTIFLSWVILRERFTKVEALGSLISLLGVVLIVRPSFLFGTPELTDSSSQIVESSDPKSRLIATLVGLWGVLGMSCVYIIIRYIGKRAHAIMSVSYFSLITAIVSFIGINTIPSMKFQIPHSKKQWILFGNLGVSGFIFQLLLTMGIQRERAGRGSLMTYTQLLYAVFWDVALYKHWPNIWSWIGMIIIISATLWVIRIRAANNETTAKDLTPIIDDEENSIPLTEFDLSDSK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .: .* . . * :*:. :* :: * : .* : . ::.::: .* * : : : : : * *.** * .:: :*: .::** :* * * :. ::: *:* : :.: ::: **:**.**.*:** . :. : . : .....: .: : . :::* : * . : : : : :.: : * . : :. :*: .: *:::* .:* *:** :: ::::*..::: :: . *. :: * : :: : . : ", "identical_positions": 43, "similar_positions": 122, "identity": "10.24%" }, { "cls_id": "homologset.agr.SGD:S000004872", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L617-1", "uniprot_id": "A0ABK0L617_RAT", "id": "A0ABK0L617-1", "name": "tRNA (32-2'-O)-methyltransferase regulator THADA", "aln": "MGVKKKREMQFAALTVCHQDLETLRSFADVEGKNLASLLLHCVQLTDGVSQIHSVKQIVPLLEKVD--KNGVCDPIIQRCLDILASIYFSLTLKNPLKKVLASSLNGLPECFLNEAAHSFTFHLQEELDTADLHSYRKVMDNISSCMENFNLGRASVVNLLQNVLHFLQKSLIEVQEENRVLRHRKFAGNHIVQTQLMNDLLVGVRVAMTLVQKVQGPQSNLWNDSSSPIWQSMCGLLSIFTRFLNDDDLLQTIQSTSGLAVILFIKTMFRPSEK-LPGLISSLLLQSADCTSIPDWLMSSCRSLCCADVPASALLFLCQGTLAMLDWQDGSMGPSREALLLDTVHVLFTLSSQIKESTLEMFLSRILASWTNSAIQILESSSPSLKDHLNGDSSIPRRLLEYVYTHWEHPLDALRHQTKIIFRNLLQMHRLTIEGADLVTDPFFLELTKSLLQLEWHIKGKYACLGYLVESLGIEHILAIDKTIPSQILEVMGDQSLVPYASDLLETMFKN------HKSHLKSQTVTNTWMDKWHETWVFPVLSVLCGGNLDQRSYVIDYYLPRLLNYSPESLHYMVQILQTPIDTETG---------SCNHRGALGALMACLRTARAHGHLQSATHAWENLVCSARVKQGLIHQHCQVRIDTLGLLCESSRSTEVVSREEMQWVQFFLTYNLNSQSPGVRQQICSLLTKLFCRIQESSQVLYKLEQRNSTPDSEKRSTREQPSVSLQQYKNFMSSVCNILFEALFPGSSYSTRFSALTILGSIAEVFPASKGNIQTVYQLSHDIDAGRFQILMECFTSTFEEVKTLAFDLLMNLSSVTAGQLQGSEKLQDLFQAALELSTSTKPYDCVTASY-LLNLLIWQDALPASLSASSAQQPTCGAGEK-SAVVERNTLVVIKCLMENLEDEISQAENSLLQAASSFPMYGRVHCITRAFQKLPLHDLRLVSEWKPVLGKLLLLSYRLSTVVSPVIQ-SSSPEGLIPMDTDSESASRLQVILNEIQPRDTNDYFSQAKILKECDSFDLEDLSTSVSNIDSSAEIKGKEEKACDVTAQMVLTCCWRSMKEVALLLGTLCQLLPLQ------PVPESAAGLLTVQQVKEIGEYFKQHLLQSRHRGAFELAYTGFVKLTEILNRCSNVSLQKLPEQWLWSVLEEIKSSD----PSSKLCATRRSAGIPFYIQALLASEPKKGRMDLLRVTMRELISLALS-ADDSKGR---VPQVHALNILRALFRDTRLGENIIPYVAGGAKAAILG-FTSPVWAVRNSSTLLFSSLITRVFGVKRG---KDELSKTNRMTGREFFSRFPELYPFLLKQLETVANTVDSDLGDPDGHPG-------MFLLLLVLERLYPSPMDGTASTLSLAPFVPFIIRCGRSPFYRSREMAARALVPFITIDQIPSTLHALLDSLPSSTDQCFRQNHIHGTLLQVFHLLQAYITDSKHRINADFLQELSDITVCTKAKLWLAMRQNPCLVTRAVYIDILFLLTHCLDRPEEGKHTALESLDFWEDVRRIILGSELITGFPWTFKVPGLPQYLQSLTKLAIPEVWASLAEAEGQATAVPLSFSQLLKSSFPEVRLLALDALLER--AASSEQGQKGPPPLLYSMGEEFLLLAMKEDHPGCFCRVLKILYHLNPSEWLPQTECSVHLSPKEFLVWTMDIASNDRSEIQGVSLRLASKIIAYLVQSCEKNKDSVALELRRWVQLIVWSCGDHLPTASRLAVAEVLSGTAPLFLTSPQPILDLQDTLSLWRCVLTLLQSEEQPVREAATETVTTAMSQGNTCQSTEFAFCQVDASIALTLAFAVLCDLLQQWDQLGPGLPILLGWLLEEGGDLKDLMQSPHQGEEEHIFEKSEVNFWAETLTFVKYLCNQVFHLLCQSGCQSSHSQ-LSHLQRTASEQHRLISQLFRELPLS--------AEFLKTVEYTRLRIQEERTLAVLRLLACLEGKEV-----LRAEDCPREWRQEMAPRTEAAC---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8C756-1", "uniprot_id": "THADA_MOUSE", "id": "A8C756-1", "name": "tRNA (32-2'-O)-methyltransferase regulator THADA", "aln": "MGVKKKREMQVAALTVCHQDMETLRSFADMEGKNLASLLLHCVQLTDGVSQIHSIKQIVPLLEKVD--KNGVCDPAIQSCLDILAGIYFSLTLKNPLKKVLASSLNGLPEVFLTQATHSFTFHLQEELDTADLYSYRKVMDNISSCMENFNLGRASVVNLLKDVLHFLQKSLIEILEEN-----RKFAGNRIVQTQLMSDLLVGVRVAMTLVQKVQGPQGSLWNDSSSPIWQSMCGLLSIFTKFLNDDDLLQTVESTSGLAVILFIKTMFRPSEK-LPGLISSLLLRSAECTSIPEWLMNSCRSLCCTDVPASTLLFLCQGTLAMLDWQDGSMGPSGEALLLDIVHVLFTLSSQIKESTLDMFLSRILASWTSSAIQILESGSSGLKGHLNGDSCVPRRLLEYVYTHWEHPLDALRHQTKVMFRNLLQMHRLTMEGADLATDPFCLELTKSLLQLEWHIKGKYACLGCLVETLGIEHILAIDKTIPSQILEVMGDQSLVPYASDLLETMFKN------HKSHLKSQTVTNTWMDKWHETWVFPVLSVLCGGNLDQRSYVIDYYLPRILNYSPESLHYMVHILQASTDTGTG---------SCNHRGALGALMACLRTARAHGHLQSATQAWENLVCSARVKQGLIHQHCQVRIDTLGLLCESNRSTEVVSTEEMQWVQFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQRKSTPDSENGSIREQPSVTLQQYKNFMSSVCNILFEALFPGSSYSTRFSALTILGSVAEVFPDPEGNIQTVYQLSHDIDAGRYQILMECFTSTFEEVKTLAFDLLMKLSSVTAGQFQDSEKLQDLFQAALELSTSTKPYDCVTASY-LLNLLIRQDALPAVLSASSPQQLTRGAGET-SAVLERNTLVVIKCLMENLEDEISQAENSLLQAASSFPMYGRVHCITRAFQRLPLNDLRLASEWRPLLGRLLLLSYRLSTVVAPVIQ-SSSPEGLIPVDTDSASASRLQLILNEIQPRDTNDYFNHTKILKECDSFDLEDLSTSVSNIDSSAEVKGKEEKACDVTAQMVLACCWRSMKEVALLLGTLCQLLPVQ------PGPESSNVFLTVQQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEILNRCSNVSLQKLPEQWLRSVLEEIKGSD----PSSKLCATRRSAGIPFYIQALLASEPKKSRMDLLKITMRELISLALS-ADDSKGR---VPQVHALNILRALFRDTRLGENIIPYVAGGAKAAILG-FTSPVWAVRNSSTLLFSSLITRVFGVKRG---KDEVSKTNRMTGREFFSRFPELYPFLLKQLETVASTVDSELGEPDRHPG-------MFLLLLVLERLYPSPMDGTSSALSLAPFVPFIIRCGRSPIYRSREMAARALVPFIMIDQIPSTLCALLNSLPNSTDQCFRQNHIHGTLLQVFHLLQAYITDCRHRTNADFLQELSDVTACTKAKLWLAMRQNPCLVTRAVYIDILFLLTNCLDRPEEGKQTALESLGFWEDVRRIILESELIKGFPWTFKVPGLPQYLQSLTKLAIPEVWASLAEAKGQATAVPLSFSRLLKSSFPEVRLLALDTLLER--ARSSEQEQKEPLPLLCSMGEELLLLAMKEDHPGCFCRVLKILYHLNPSEWLPQTECYAHLSPKEFLMWSMDIASNDRSEIQGVALKLASKIIAYRVQSCEKNKDSLAPELRQWVQLVVWSCGDHLPTASRLAVAEVLTSTAPLFLTSPQPILELQGTLSLWRCVLTLLQSEEQTVREAATEIVTTAMSQGNTCQSTEFAFCQVDASIALTLALAVLCDLLQQWDQLEPGLPILLGWLLEEGDDLEGHVQSPHQGEEEHIFEKSEVNFWAETLTFVKSLCRQLFHLLCQSGWQSPHSQKLCHLQRIASEQSHLISQLFRELPLS--------AEFLKTVEYTRLRIQEERTLAVLRLLACLEGKEG-----LRAEDCPREWRQVMAPRTEAAC---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6YHU6-1", "uniprot_id": "THADA_HUMAN", "id": "Q6YHU6-1", "name": "tRNA (32-2'-O)-methyltransferase regulator THADA", "aln": "MGVKKKKEMQVAALTICHQDLETLKSFADVEGKNLASLLLHCVQLTDGVSQIHYIKQIVPLLEKAD--KNGMCDPTIQSCLDILAGIYLSLSLKNPLKKVLASSLNSLPDFFLPEAMHRFTSRLQEELNTTDLYSYRKVTDNISSCMENFNLGRASVNNLLKNVLHFLQKSLIEILEEN-----RKCAGNHIIQTQLMNDLLVGIRVSMMLVQKVQDFQGNLWKTSDSPIWQNMCGLLSIFTKVLSDDDLLQTVQSTSGLAIILFIKTMFHPSEK-IPHLISSVLLRSVDCTSVPEWFMSSCRSLCCGDISQSAVLFLCQGTLAMLDWQNGSMGRSGEALLLDTAHVLFTLSSQIKEPTLEMFLSRILASWTNSAIQVLESSSPSLTDSLNGNSSIVGRLLEYVYTHWEHPLDALRHQTKIMFKNLLQMHRLTVEGADFVPDPFFVELTESLLRLEWHIKGKYTCLGCLVECIGVEHILAIDKTIPSQILEVMGDQSLVPYASDLLETMFRN------HKSHLKSQTAESSWIDQWHETWVSPLLFILCEGNLDQKSYVIDYYLPKLLSYSPESLQYMVKILQTSIDAKTGQEQSFPSLGSCNSRGALGALMACLRIARAHGHLQSATDTWENLVSDARIKQGLIHQHCQVRIDTLGLLCESNRSTEIVSMEEMQWIQFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQSKSKREPENELTKQHPSVSLQQYKNFMSSICNSLFEALFPGSSYSTRFSALTILGSIAEVFHVPEGRIYTVYQLSHDIDVGRFQTLMECFTSTFEDVKILAFDLLMKLS-KTAVHFQDSGKLQGLFQAALELSTSTKPYDCVTASY-LLNFLIWQDALPSSLSAYLTQQVACDNGDRPAAVVERNTLMVIKCLMENLEEEVSQAENSLLQAAAAFPMYGRVHCITGALQKLSLNSLQLVSEWRPVVEKLLLMSYRLSTVVSPVIQ-SSSPEGLIPMDTDSESASRLQMILNEIQPRDTNDYFNQAKILKEHDSFDMKDLNASVVNIDTSTEIKGKEVKTCDVTAQMVLVCCWRSMKEVALLLGMLCQLLPMQ------PVPESSDGLLTVEQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEVLNRCPNVSLQKLPEQWLWSVLEEIKCSD----PSSKLCATRRSAGIPFYIQALLASEPKKGRMDLLKITMKELISLAGP-TDDIQST---VPQVHALNILRALFRDTRLGENIIPYVADGAKAAILG-FTSPVWAVRNSSTLLFSALITRIFGVKRA---KDEHSKTNRMTGREFFSRFPELYPFLLKQLETVANTVDSDMGEPNRHPS-------MFLLLLVLERLYASPMDGTSSALSMGPFVPFIMRCGHSPVYHSREMAARALVPFVMIDHIPNTIRTLLSTLPSCTDQCFRQNHIHGTLLQVFHLLQAYS-DSKHGTNSDFQHELTDITVCTKAKLWLAKRQNPCLVTRAVYIDILFLLTCCLNRSAKDNQPVLESLGFWEEVRGIISGSELITGFPWAFKVPGLPQYLQSLTRLAIAAVWAAAAKSGERETNVPISFSQLLESAFPEVRSLTLEALLEKFLAAASGLGEKGVPPLLCNMGEKFLLLAMKENHPECFCKILKILHCMDPGEWLPQTEHCVHLTPKEFLIWTMDIASNERSEIQSVALRLASKVISHHMQTCVENRELIAAELKQWVQLVILSCEDHLPTESRLAVVEVLTSTTPLFLTNPHPILELQDTLALWKCVLTLLQSEEQAVRDAATETVTTAMSQENTCQSTEFAFCQVDASIALALALAVLCDLLQQWDQLAPGLPILLGWLLGESDDLVACVESMHQVEEDYLFEKAEVNFWAETLIFVKYLCKHLFCLLSKSGWRPPSPEMLCHLQRMVSEQCHLLSQFFRELPPA--------AEFVKTVEFTRLRIQEERTLACLRLLAFLEGKEGEDTLVLSVWDSYAESRQLTLPRTEAAC---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWB9-1", "uniprot_id": "THADA_DROME", "id": "Q9VWB9-1", "name": "tRNA (32-2'-O)-methyltransferase regulator THADA", "aln": "---MNDLNLRVAALKVCAHPKR----FAELRDALVPLPNTWIAAPHDFVLQFAAAKSSAEQVQVVKDVFYGEQAQDHEDVAHFLADLLLASPLKHAVRNQLTKLFS--DNALAKQNASPHRRHSKEHLLEALQQSLGEMANSLAVITP--PVSHERTNDVFVSANACLQNFPFGREALG-----KQVHRFAPLLTTALERYWADICDPTLELSPTRRNELYLYVQNALRFLVSLLAEWSDKLRLFEDQRFPGTSN-----AVAQKVARYYDTPWD-VRSIAALLIGHLARFSGTFKAYVEDCS-----RPKAEQDVPIQMAALLVLRPVDYTENATLALAILKRIVAVSELKSTVTN--LLVFLSKHLFIYSKSLGEMHAHLPDDQKLLYQR---ILAQLQVFALQNISSDTDSVRHMSSALLHQVLQHAQAAGQ------EELFQVVYRQFEDRAAYLNASCMALEQLVAVAGVSKSIENCPSLFGVIFPRHLG------CEDCVDALFKA------MMVSAHKTEPFAEWQSRWFG------LLLAAIRVPEKRRQVIEELIAQAVQLEPTRLAQVLLPDDR-----------------LPLSCKLAAILGVRQLSARRQNLLRG--------MKEEVEQALIGLDDHTRLLALRFLVETPRPSELLNADQMGAIELYVRHNANNPSAHLRQLGYGLLQKALKRVHFG-----LVEYRKSRTPAS------------QEVLQFLIRLIRTLAQNLFPTANYGRRWLSLRLLRDCLELSEMVG---ITFSELGIELPT---EALMACLGDSYEHNKVLAAQLLERFQSHSLFKPDE----------MIELLLSLRPSDSATGAF-QLQVYCKASRVQSEMPTPTHG----------GTIHEPLTFRALQWCLQHLREGLRLAQLDLGEAAKLNPLYGLLFASRHLLQQLKLKELAKEPQWRQYIDELVTMCLAVSSVVLPVVS-SASPEGHLPETCDQETDQPLTNVLDRQLSR--------------------------------------EELLQVRTTPQMILLCAWRSSKEVCLILGELVQRAPLEEEEDEEQQQQQGDFLLSRAQLEAIGEHFLQLLAETKHRGAFEQAYVGFTMLCRRFWHSESVRLNQLPGQWVDEAMAMVSGQEEWAGKGARLCATRRSAGMPFMLQALVGTELKLGTHATLYRCMNRLLEVCERRTGGAAGI---TARSHALNIMRALFRSSELAELVTEFMARGIQCALDGLLLAEEWAERNSATLLLAALIVRVFGVERARLETGELHVRNRMTGRIFFTRYPQLFDYFHAALQRESEQMDAGGGGSENASGKRRQAVQLEAMLLMLSRLYPSSLEGAESTLNLSEFVPFLIRICHSHDLMTREMAALVVANFVTQEQALAEIRRIVVELKALQLRLKNTEAANTKLNTNVLHGQLLLLLHLHRLVRWTRPSLTRMQLHTLAELAAPLLQHDACAFSALVAVMVAAMEDAVEPG-------LLDFQLLEQIGVVYLLN--HKEVQSRCQQLGISNRFYQIFGLHLHRLRG---ISQGIVLHIVEDLAETIWALDELKVELWLYILLQR------------------SLSEQNSLVSEQDIEHFEFSRDIRRYFETLSREQREEVGQELYESPAVRSSVLHMMHMIKSSKNSCWSLQLAGRLAALQTLLRDP-----GLELNQLVQRCSEEHSTHQEAGLLLGLRRLIGESKMLERKHWLPMLNYAQRLVHPGQPVYLRHQAAELCDSLARNHLRDQLVAG-----------TTDVDIGLVGRFSGLVLLLLHDD---------AEWVRHRAVQLVCGAGLRTRSGAGQEQEQSAMAPLILPSALIPPFLDTMIGKLTFDDFN----------------MVQRLVDIIAEPFTT--------ADAMELFDKQENNHYCERNHVLTELWDARGRADP-------------RARTPTIPTGYQIFK--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M2BCI6-1", "uniprot_id": "A0A8M2BCI6_DANRE", "id": "A0A8M2BCI6-1", "name": "", "aln": "---MTIVNFSLEDADAVLKSVVLEDQFSSDVKDTLRSFLLKLTENGRITGKRSRDRSLEEASQILQKIPKEALHSLQPPALHRLIQLILALQLEAVTTSSACRKLDQMLQVFAVINHSVVFEEVKQCLLNILHQKQVFSLKDLQIICMFLEDSTIGREVLKSECTTLLGKVAELIPVVMS----DEASRNGPLCYQMVKGCLQVFQLLPGEVAQLVYSKDSVNITAR--------GILEFLMRIILGEVSSRDTRLLAGTAVAMLLSTATDSQCAGSAAWSLLQITKTEPWRLTVGELQVNCSSRCQDGVDRLAVCRGLLTCCKNDVLVSRHSNQKTCFLLHGLLPFISALCEEKLD--CHYFVFQVFTIWLKRLKECLSEVWEVTGAPLDS--DLQHRLTQIIWRNSESPLDGVAEVARSAFCLFMEIYEKDCQHFG-TEKSLYVELLKRISELPWESKAKYLPLTAVLPYTGTNKVLELYPALPYHLLKCLSTNHLSPCASEVYKSLLQEQKRELIIIASKEAPPTDQYLANQWAHQWQPVILEALTSEITLLQNNASSHLLPTTLRTFPGAFNTLLSALNPS---------------APGHLHAWACVMSAQRATSGRSLWGAESS-----HVHQTLHLALCSLDDSVRLAALNLLCCSPKTNEAPSQLEYSALRDFIPLNLNCESSPFRQHLQAALRKFLVRIRDSCMAIIKGRNSKKGLTEEEVA-------EIEQGVEFVEWLFQLSLVYLSPDSSYQRKKTVLLLLCAVLETCTDTWSPDRKKGQPPANMSTLINWAKDRGKWDFFSKSKLLVLIGCLEDSTNEIRELSA--------ELLFRFFPSSLPDDVTCVLFSRADQLLQSPRVQEAQMGALMVKLLLQKADGVFNQGEKQSVKLITFLLSKLEQHYLTARSDMLLAARTTPVHGIVSALQRGLLEVPG--VLLESITHSIAGELVLLLEKLTLVLLGVLYGNQDTEEKDVPPSFCDMGNAISSLIGQGGVDGVG------------------------------LDEDGEENVLLSEEHSLVLTCCWVSLKEIGIFLGSLVERILSL---------HCEELKLSVEELRTASKVFKDIILKCRHWGAVEGCCVGFTKFCRALLSSSDPDIRQIPSLMLQQGLSVLQSPS-------STSVTRRAAGLPMLILGVLAAEDSSKSRPLLAHTINTLLDTAKALLPSDWDQTLDLPQVCAVHTLQALVKGSSLGVAVLQFTP-AMAVLSLTLLSSACWAMRNAALQLYSSLCTRMLGQQKA----GEGSSNSGMSAASFFHLYPALQPFLQGALETAAN--DLHDATLLLHPA-------LYPVLTLLSKLQPG---AEKQTRALSEFLPPLLLLSASPVYGVRVMSSKALVAMIPTSEYMATVLQLVKDLPESPDVVSCHNRLHGKLLQTRAILTRALRSSVS------SLSLSEVVDVFESRLWLGSSKQRCPLVRQSYVDIVRLIRGHCSAG--------FLSQLSSQLLHEIQRTPDILEIGAASFHQSTVNFLCGDPEWACQAWRSLANGNAVVQLSLVKSVTDGHGWRGTDLQQVIEGELKAN---------------------LKAALMSQSVDYRAAYLTALVEVLTPE-EESLGLSRLCPSEFEQTGLQECVELLLNDLETDRGGPALISTALCAVSVLLSQS---ADVSFLQRWCKLLEKHRCPDAPEALRSACAQSLCLCGVSVVTRSLTSSLIPKHLNTSLISTGLFLLQDESSDVRAKAAIFASLLCCSRQPEAPQRCFHMQVNQALRSLLDLLLEEFWDTSG-----ALEALLCHLPSCDLNIILKQAKDTQCRSLYEPDEANVFAEPSVISECLLPYLLRLVKHYPQSSSLAENLERWARNSAATVKENLATCMQLQLSDVLNPDWLSLLIEPHFHGALAGLFTRAIVLLQMLNDCDSIRPLLDPLSLSSDLQDIHKRFVLNGVFLPQVFIDALRTD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03496-1", "uniprot_id": "THADA_YEAST", "id": "Q03496-1", "name": "tRNA (32-2'-O)-methyltransferase regulator TRM732", "aln": "-------------------------------------------------------------------------------------------MTTDVQFSSQEIELFRVKEFLIANNPAKINNENKDAVLTQIEHDFRYLIQYIKDGLPNLNESTR-----------------------------------------------------------------------------------------------------------LIFPDTFSICLLRSHQIIASKKIDSQEFLSAVKEQLLTEAN---------------------------------------------------------------------------------------------ANIIFEYVLDFWADGGAPLMNALRDLFSKLLNLLKITYPMS--TLKDVLFNWMNEILEVPSTLRVQYYLIDALSSDFDLYYIIEKKPHFIDNSFSLMNSDLLANSVGKCIVSLLLN--------IYEKHFKKNESFVQEWIQLWKSCALKYIHDKQYT-KSINLYIMIPLFKNMPNSAFTLFLECMSNK-----------------DPSLLLSLLKIGQELGIEEEPFCDN-------KYTTVDSVNKLIEQDEYKLQVFEILTFSTKKSKPIRPFVFKTIKQYLYVFFVDTELERRNYFCSSMKHFIFRTRDCAYSLARDARKLKKAEKFPDEQREK-LAQVEEARAFLVWLCNFIKYNLAPGTLYQANVTSLKLMHILIKSG-------VDKSTPQKFLDNQNKREYPFSIPILQDVTFLRLLIDLLVSNYADVRELSK------------EMLFIMISADESRGLFLDTLDANALKWTATSLLSDYEKGDAGATVYEFIFTVMGSQRSFIDQTIDILAQMVQNLQNDSIGCAENS-IGPHFAALSLILNKFNSEENHQDT--SKIISKLINLVLKSWEATRNVVC-HDSAHGILP-----------------------------------------------------------EKYANCGVPDQVIISHAFRAIKEASYLLETILKKYPLT-----------------RDQLDSIGDLFIVQLSTIRHSGAFQAVLPGLKAFCIRCQ----LEFPAILEELLSKSVKSLKSKT--------QHITRRSGGLPFLVTTVLSAEVTKGR-PLLQKTFENLLLVARLPIPPHQDEFD-LPQVNAINCINAIFVEPKLSVHCTSFVSEALELALLN-FDCDIWALRNCSIMLFTSLQNRIFG-----------KVGRSVSAKLFFTKYSGLRQLLLNILNSSIAQYSGSERKSYQIES-------IFLVLNVLLRLRPT-----AGYTGLKEFNVSVYECLSNENWKIRDMASRVLH--MLSENFEEEIRKLLDLAS-----IAKQNQLHGHLLALQQLVPQYLSGTRD----------MELIQRILEKKRMLLLENKCFITKKAYLKLTCCILETCDIP-------------------DSILKDYISTLRNTFIAENNEYVVDGSKQLYLAQILDMLLKYEDS-IYLDDICLLGLYSPFYEAQLSTLQYMNTN-----------------------FHWETTRNSEFLEQLQLLLRVPDLLPMAKALVVKILSRKKNTLSLTTCTDLLKTNNSED--------TKLAAVSSLSAKLS----SQTFHQVWNLLQGFFADSCSKDFRLASLECLTAYPESCKNSR---ILLQLYNFLWDDDSEIREKASFYLNKNFIQTADWEYNRNTSVTALIFTKKFVDVFTSSEVVEELCLQLFQYLN------EYDMFAAEESAKNCLFTIEKDNQFINELQKAMHILNMIKLTGRDISKCYKDQIHHLKS------------------ALLEHFNTEDFKDSPLG----------------WCSNAEIFSRITLLKELIQHYSPSDYEN-----FINVLTKHSVHPLIISYSQL---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : . :: : . . : . : .. : : . : .:: . . . . : . . : : . : : : . ::: . ..* * : :. : .: . . : . . . :: .: :* : : .: :. :: . *: . : : : * : . :: *: : . * * : * . * :: : : . . . . .: . * : : :. * : . . .* : . . : .. . .*: : . *: ... :: .::: .: : ** :* : : :: .. * : :* **.: *: : : : : . : :. ***:.*:*: : ::.:* . * :. *: . . .: *:: :.*:. . *. : . . : . ** **.: * ::* *::* ::. ** :. * : *: . . : :* :* :* . : * : . * *:: .: : .. : :: : : * : . :: . : : . . . . . : : . : : : . . : : :.: : . . : . : :. . : . . : . : : : : * .: ", "identical_positions": 54, "similar_positions": 255, "identity": "2.68%" }, { "cls_id": "homologset.agr.SGD:S000004873", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7EZM1-1", "uniprot_id": "F7EZM1_RAT", "id": "F7EZM1-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEAMCFDGVKRLCHIRGKLRKKVWINTSDIILVGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGP-GDDDE-IQF-----DDIG-DDDED-IDDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47813-1", "uniprot_id": "IF1AX_HUMAN", "id": "P47813-1", "name": "Eukaryotic translation initiation factor 1A, X-chromosomal", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEAMCFDGVKRLCHIRGKLRKKVWINTSDIILVGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGP-GDDDE-IQF-----DDIG-DDDED-IDDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BMJ3-1", "uniprot_id": "IF1AX_MOUSE", "id": "Q8BMJ3-1", "name": "Eukaryotic translation initiation factor 1A, X-chromosomal", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEAMCFDGVKRLCHIRGKLRKKVWINTSDIILVGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGP-GDDDE-IQF-----DDIG-DDDED-IDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14602-1", "uniprot_id": "IF1AY_HUMAN", "id": "O14602-1", "name": "Eukaryotic translation initiation factor 1A, Y-chromosomal", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEALCFDGVKRLCHIRGKLRKKVWINTSDIILVGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGP-GDDDE-IQF-----DDIG-DDDED-IDDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60872-1", "uniprot_id": "IF1A_MOUSE", "id": "Q60872-1", "name": "Eukaryotic translation initiation factor 1A", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGP-GDDDE-IQF-----DDIG-DDDED-IDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6VV72-1", "uniprot_id": "IF1A_RAT", "id": "Q6VV72-1", "name": "Eukaryotic translation initiation factor 1A", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGP-GDDDE-IQF-----DDIG-DDDED-IDDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "J3QMW5-1", "uniprot_id": "J3QMW5_MOUSE", "id": "J3QMW5-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGA-GDDDE-IMF-----DDIG-EDDED-IDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "J3QPI8-1", "uniprot_id": "J3QPI8_MOUSE", "id": "J3QPI8-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGA-GDDDQ-IVF-----DDIG-EDDED-IDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VLT7-1", "uniprot_id": "A0A1Y7VLT7_MOUSE", "id": "A0A1Y7VLT7-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGP-GDDDE-IVF-----DDIG-EDDED-IDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "J3QQ02-1", "uniprot_id": "J3QQ02_MOUSE", "id": "J3QQ02-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGP-GDDDE-IVF-----DDIG-DDDED-IDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VNG9-1", "uniprot_id": "A0A1Y7VNG9_MOUSE", "id": "A0A1Y7VNG9-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGP-GDDDE-IVF-----DDIG-DDDED-IDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VK80-1", "uniprot_id": "A0A1Y7VK80_MOUSE", "id": "A0A1Y7VK80-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARNLKAYGELPEHAKINETDTFGP-GDDDE-IVF-----DDIG-DEDED-IDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VJE9-1", "uniprot_id": "A0A1Y7VJE9_MOUSE", "id": "A0A1Y7VJE9-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPEEARNLKAYGELPEHAKINEMDTFGP-GDDDE-IVF-----DDIG-DEDED-TDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "J3QP87-1", "uniprot_id": "J3QP87_MOUSE", "id": "J3QP87-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGA-GDDDE-IVF-----DDIG-DEDED-IDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "J3QNT6-1", "uniprot_id": "J3QNT6_MOUSE", "id": "J3QNT6-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGA-ADDDE-IVF-----DDIG-DDDED-IDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F6YNI8-1", "uniprot_id": "F6YNI8_MOUSE", "id": "F6YNI8-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGP-GDDDE-IVF-----DDTG-DDDED-IDDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VEA1-1", "uniprot_id": "Q9VEA1_DROME", "id": "Q9VEA1-1", "name": "Eukaryotic translation initiation factor 4C", "aln": "MPKNKGKGGKNRRRGKNENEFEKRELIFKEDQQEYAQVTKMLGNGRLEAMCFDGVKRLCHIRGKLRKKVWINQGDIILVGLRDYQDSKADVILKYTPDEARNLKTYGEFPESVRINETVTFVEDGFDED-IEFG----DEISSEDDADSVDNI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38912-1", "uniprot_id": "IF1A_YEAST", "id": "P38912-1", "name": "Eukaryotic translation initiation factor 1A", "aln": "MGKKNTKGGKKGRRGKNDSDGPKRELIYKEEGQEYAQITKMLGNGRVEASCFDGNKRMAHIRGKLRKKVWMGQGDIILVSLRDFQDDQCDVVHKYNLDEARTLKNQGELPENAKINETDNFGFESDEDVNFEFGNADEDDEEGEDEELDIDDI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *:: ****: ****:.: ****::** *****: **** :*: **** :*:.:***** ****:. .****:.*:*:**.:.*:: **. :***.** **: * .:*** .* . :: : * *: ::: *:*", "identical_positions": 67, "similar_positions": 43, "identity": "43.79%" }, { "cls_id": "homologset.agr.SGD:S000004874", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y119-1", "uniprot_id": "Q9Y119_DROME", "id": "Q9Y119-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------MPDTEIIVTNAGE----PSTKASLIVVSN--------RLPFVLIRDP-----KTDELERRASAGGLVTAVCPVVIKGSGLWVGWSGIHLKDPNEAIPESNPNDQTPTAG------------------------LKSEQVVSVNIDSKIFDSY----YNGCCN-----------------KIFWPLFHSMPGRANFG-----------------------------------------GEHWHDYVTVNKHFAVR-----------------------------------TIEALEKCLAKNQGSEKSPPIVWIHDYHLMLAANWVREHAEEKNLPCRLAFFLHIPFPPWDIFRLLPWSDEILQGMLGCDLVGFHIQDYCLNFVDCCQRNLGCRVDRNNLLVEHGGRTVRVRPLPIGIPYERFVN-------LATTAPKVLKTSKMQIILGVDRLDYTKGLVHRLMAFEALLLKYPQHKEKVSLLQISVPSRTDVKEYRELKEEVDQLVGRINGRFTTANWAPIRYIYDYVSQDELAALYRDAAVCLVTPLRDGMNLVAKEFVACQINEVPGVLVISPFAGAGEMMHEALLCNPYEVNEAAEVIHRALTMPEDERVLRMARLRRREAECDVSHWMR-CFLKAVGALEMDDVGTTIMQPVSVDDFDDYLLKYIGYNHKLALLLDYDGTLAPIAPHPDLATLSPEIKNVLYKLSNHSDVYVAVISGRNVDNVKKMVGIEGITYAGNHGLEILHPDG---SKFVHPMPMEYEKKVSDLLKALQDSVCRDGAWVENKGALLTFHYRETPNHLRGAMVDKARSLIEKYGFKATEAHCALEARPPVQWNKGRASIYILRTSFGVDWNERIKIIYVGDDLTDEDAMVALKGMARTFRVTSSDIVKTAADHRLPSTDSVYTLLKWVERHFMGRKARANSLTYRPTKGDGVQMQMSLEVAASANNLEV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38426-1", "uniprot_id": "TPS3_YEAST", "id": "P38426-1", "name": "Trehalose synthase complex regulatory subunit TPS3", "aln": "MTIIVASLFLPYTPQFEADVTNSDTAKLVESSMIKVDCNNQELSNNKQERSSSVTSASSHYIGLPQEAQINGEPLQRANVGSPATGVNYHNEMEMLSSEQFLEELTANATHAANSGIPPANNPVSSGSTAQRPSVEEFFSAPSARVCSPSQEASASSISASRSSAHHNDLSSSLMKNPNLSFDSHPPRVRSSSKSAVITPVSKSVPDVDPAVVDVAKVREEFQQQASLPSMKRVSGSTAGDSSIASSSSNLRYSQQFQDNFIEDTDSEDDIDSDLETDATKKYNVPKFGGYSNNAKLRASLMRNSYELFKHLPWTIVDSDKGNGSLKNAVNIAVAEKTVKEPVSWVGTMGIPTDELPHEVCHKISKKLEQDFSSFPVVTDDITFKGAYKNYAKQILWPTLHYQIPDNPNSKAFEDHSWDYYQKVNQKFSDRIVSVYKPGDTIWIHDYHLMLVPQMVREKLP----KAKIGFFLHVSFPSSEVFRCLANRERILEGIIGANFVGFQTKEYKRHFLQTCNRLLAADVSND--EVKYHCNIVSVMYAPIGIDYYHLTSQLRNGSVLEWRQLIKERWRNKKLIVCRDQFDRIRGLQKKMLAYERFLIENPEYIEKVVLIQICIGKSSDPEYERQIMVVVDRIN-SLSSNISIS--QPVVFLHQDLDFAQYLALNCEADVFLVDALREGMNLTCHEFIVSSFEKNAPLLLSEFTGSSSVLKEGAILINPWDINHVAQSIKRSLEMSPEEKRRRWKKLFKSVIEHDSDNWITKCFEYINNAWESNQETSTVFNLAPEKFCADYKAS---KKHLFIFKISEPPTSRMLSLLSELSSNNIVYVLSSFTKNTFESLYNGVLNIGLIAENGAYVRVNGSWYNIVEELDWMKEVAKIFDEKVERLPGSYYKIADSMIRFHTENADDQDRVPTVIGEAITHINTLFDDRDIHAYVHKDIVFVQQTGLALAAAEFLMKFYNSGVSPTDNSRISLSRTSS------SMSVGNNKKHFQNQVDFVCVSGSTSPIIEPLFKLVKQEVEK---------NNLKFGYTILYG----SSRSTYAKEHINGVNELFTILHDLTAA----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *..* :.: .. ** :** :* *. *:::* . * :* ..::*.*. * . . *. : :: : ::* * . . .*** .**: :. ::::. ..* :.* .* :: *.:..* *...: :.: .: .*...::.: :. :* : . *. :*********..: ***: .::.****:.**. ::** *. :.**:*::*.::***: ::* :*:: *:* *.. *..: *:: . * * **** * ::.. * : : ::*: *::* :** ::::*:* :*:: *:: *** *:**.: . :* : *:: **:: :...:: : *: :::: :. : ** :* * ** .**:****..:**:...::: . :*: . ..:. : . *:* **:::*..*: *:*:* *. :*: * :* : * * .:*: ** .* * :: :*::: .. . ** . :* : : :. * :: .:*:: . :. .....:* .*:. : : * ::* * . *: :: . .: *. :* .* * ...::: :.. :. * :*. :: * *.* :::: *: : *. :: . ...: * : *** :.: ..: :: :*.:.* : .: . .:** .:: . **: : * :. ** : :**: ::: :* ", "identical_positions": 169, "similar_positions": 313, "identity": "15.52%" }, { "cls_id": "homologset.agr.SGD:S000004875", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3U1C6-1", "uniprot_id": "TATD3_MOUSE", "id": "Q3U1C6-1", "name": "Putative deoxyribonuclease TATDN3", "aln": "---------------------------------------------MGLGLVDCHCHLSASDFDNDLDDVLEKARKANVMALVAVAEHAGEFERIMQLSERYNGFVLPCLGVHPVQELSPEKPRSVTLKDLDVALPIIEKYKDRLL-AIGEVGLDFTPRYAG--------------TDEEKEEQRQVLIRQVQLAKRLNVPLNVHSRSAGRPTISLLREQGAEQVLLHAFDGRPSVAMEGVRAGYYFSIPP-----------SIVRSGQKQKLVKQLPLSSICLETDSPALGPEKLTRNEPCNISIAAEFIAQVKGISVEEVREVTTRNAFRLFPKLQSLLQKELQSHPLQAKSAQGSAGESKGLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R5U3-1", "uniprot_id": "M0R5U3_RAT", "id": "M0R5U3-1", "name": "", "aln": "MLPSLELSCTGPTGNLIDCSRKVPPRLPRPQSSALVPVEKPSGVAMGLGLVDCHCHLSAPDFDSDLDDVLEKARKANVMALVAVAEHAGEFEKIMQLSERYNGFILPCLGVHPVQELSPEKTRSVTLKDLDVALPIVENYKDRLL-AIGEVGLDFSPRYAG--------------THEEKEEQRQVLIRQVQLAKRLNVPLNVHSRSAGRPTISLLREQGAEKVLLHAFDGRPSVAMEGVRAGYYFSIPP-----------SIVRSGQKQKLVKQLPLSSLCLETDSPALGPEKLTRNEPCNISIAAEFIAQVKGISVEEVREVTTQNAFKLFPKLQYLLQK-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q17R31-1", "uniprot_id": "TATD3_HUMAN", "id": "Q17R31-1", "name": "Deoxyribonuclease TATDN3", "aln": "------------------------------------------MRAAGVGLVDCHCHLSAPDFDRDLDDVLEKAKKANVVALVAVAEHSGEFEKIMQLSERYNGFVLPCLGVHPVQGLPPEDQRSVTLKDLDVALPIIENYKDRLL-AIGEVGLDFSPRFAG--------------TGEQKEEQRQVLIRQIQLAKRLNLPVNVHSRSAGRPTINLLQEQGAEKVLLHAFDGRPSVAMEGVRAGYFFSIPP-----------SIIRSGQKQKLVKQLPLTSICLETDSPALGPEKQVRNEPWNISISAEYIAQVKGISVEEVIEVTTQNALKLFPKLRHLLQK-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q503T5-1", "uniprot_id": "TATD3_DANRE", "id": "Q503T5-1", "name": "Putative deoxyribonuclease tatdn3", "aln": "---------------------------------------------MARGFIDCHCHISASEFTTDTDDVLLRAKKAGVKALVAVTEGASEFEKVIQLSKTYPGFVFPCFGIHPLQG-SGQDLHSVRVQDLDPFLYLFQTYKDDIV-AIGEIGLDFTPWYSS--------------ITQERDEQMKVFIKQLEISKELDLPVNVHSRSSAKVTIATMKELGIRQALLHNFAGKPSVAMEGVQAGFCFSFPP-----------AVSKNEQRAKLIRQIPLEHVCLETDSPALGLDKHVRNEPSNVTISCEYIAKVKGISSDVVMEVTTQNALRLFSKLKI---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38430-1", "uniprot_id": "YM8C_YEAST", "id": "P38430-1", "name": "Uncharacterized deoxyribonuclease YMR262W", "aln": "-----------------------MNKLVDAHCHVITDPDNTFCGDDGGSQGTLRCVMSSNPYDWNNLKKLAGRSTSKNDICVGFGVHP-WYSHLFYVGSRRDKVSHYQDVLEYKNEEQFDSLVQVLPEPLDLEEYIKREFNDTLVSVIGEIGLDKLFRLPANGFYMQNEKARLTTVKVKLSHQETVFRRFCRLARHTSKPISIHDVKCHGKLNDICNEELLTYHSVKICLHSYTGSKETLLGQWLKKFPPDRIFVSLSKWINFKDPEEGDALVRSLPSTCILTETDYPIDNPDPSYQK---ALTEQLQYLNAQIARAWDETLDAS-QAALRVYENFQKFIK------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :* :*: : : . * .: *.. . :.::: :.. . :. : :. .* : ** : . ::* :: .***:*** .. : ..* *: : .:::. . *:.:*. .. .* :: : : * : . : .:** . : *::.:* : *** * . : :: :: ::: . : : . :.: : *:::: ::: ", "identical_positions": 29, "similar_positions": 97, "identity": "7.95%" }, { "cls_id": "homologset.agr.SGD:S000004879", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0AB32TIS3-1", "uniprot_id": "A0AB32TIS3_DANRE", "id": "A0AB32TIS3-1", "name": "", "aln": "--MSS-----WWGQLSESVNNST---VRLDNTSCFSSTQ-STVLKGVNFGGIPVVLLLDFTVFILLLSIFTLIRRKLWDYGRLALVAETDVFGDGRKRRYSRLT-----------------------SSMS-VEEPE-YEKGCCSWLTFIVNMDETLVQERCGVDAVHYLSFQKHLVTLLLIICVLSVSIILPVNLSG--DLLGTDPYNFGRTTIGNLQHDDKLLWLHTVFAVLYLMITVFLLRRYTSKMKGTKREIVRNTLFVRPLPRTSTD-DSIKTHFMEAYPSCHVTSVNLCYDVAKLIDVNKNRKRAEKNLRHYNRILQQLGRRELINPRPCSHLCCCCQRCQGCEEVDAIEFYSSQEAALHEEEVRLK-QGELHPLGMAFVTLQNEYMATYILKDFNALECGGGARGVVGEEMSRGIKCGCGREPQPSTRSAELGVPKWKVNYASHPHNIYWENLSVRGWRWLLRCVLLNTALFVLLFFLTTPSIIISTMDKFN----------VTMPIYYLNSPIISQFFPTLMLWTFSALLPTIVYYSTLGEAHWTRSSENMSMMYKLYTFLIFMVLILPSLGLTSLAVFFRWLFDKQS--EGQLRFECVFLADQGAFFVNYVIAAALVGSGMELLRLPGLLLYIVRLALASSAAERKYVKQNQAYEFQYGAMYGWTLCVFTVIMAYSIVCPLIVPFGLLYLLLKHLVDKHNLYFAYLPARLDRQVHL-GAVNQALAAPIICLIWLYFFSVLRTGFM----TGTSLFTLVVLCITVFICISYTCFGHFKYLSPHNYNVKEEDEDADIV-SENSSG---LVYLPKVLNP-------------DASFESSDECSPSHSYGTT-------DISPQFIGTEESSPDSDI--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q91YT8-1", "uniprot_id": "TM63A_MOUSE", "id": "Q91YT8-1", "name": "Mechanosensitive cation channel TMEM63A", "aln": "--MTSSPFLDPWPSKAVFVRERLGLGERPNDSYCYNSAKNSTVLQGVTFGGIPTVLLLDVSCFLFLILVFSIIRRRFWDYGRIALVSEA-----GSEARFQRLS-----------------------SSSSGQQDFE-NELGCCPWLTAIFRLHDDQILEWCGEDAIHYLSFQRHIIFLLVVISFLSLCVILPVNLSG--DLLGKDPYSFGRTTIANLQTDNDLLWLHTVFSVIYLFLTVGFMWHHTRSIRYKEESLVRQTLFITGLPREARK-ETVESHFRDAYPTCEVVDVQLCYSVAKLIYLCKERKKTEKSLTYYTNLQAKTGRRTLINPKPCGQFCCC--EVQGCEREDAISYYTRMNDSLLERITAEESRVQDQPLGMAFVTFREKSMATYILKDFNACKCQG---------------LRCKGEPQPSSYSRELCVSKWTVTFASYPEDICWKNLSIQGVRWWLQWLGINFSLFVVLFFLTTPSIIMSTMDKFN----------VTKPIHALNNPVISQFFPTLLLWSFSALLPSIVYYSTLLESHWTRSGENRIMVSKVYIFLIFMVLILPSLGLTSLDFFFRWLFDKTSS-ETSIRLECVFLPDQGAFFVNYVIASAFIGSGMELLRLPGLILYTFRMIMAKTAADRRNVKQNQAFEYEFGAMYAWMLCVFTVIMAYSITCPIIVPFGLIYILLKHMVDRHNLYFAYLPAKLEKRIHF-AAVNQALAAPILCLFWLFFFSFLRLGLT----APATLFTFLVVLLTILACLLYTCFGCFKHLSPWNYKTEESASDKGSE-AEAHVPPPFTPYVPRILNG-------------LASERTALSPQQQQTYGAIR------NISGTLPGQPVAQDPSGTAAYAYQES------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CBX0-1", "uniprot_id": "TM63C_MOUSE", "id": "Q8CBX0-1", "name": "Osmosensitive cation channel TMEM63C", "aln": "--MSAFP-----DSMDQKFHNMT-------VNECFQSRS--TVLQGQPFGGIPTVLVLNIILWVFVVLLYSFLRKAAWDYGRLALLIHNDSLTSLIYGEQSEKS-----------------------SPSEVSLEAERRDRGFSSWFFNSLTMRDRDLINKCGDDARIYITFQYHLIIFVLILCIPSLGIILPVNYIG--TVLDWN-SHFGRTTIVNVSTESKFLWLHSLFAFLYFLINLAFMGHHCLGFVPKKSLHFTRTLMITYVPTEIQDPEIISKHFHEAYPGCVVTRVHFCYDVRNLIDLDDQRRHAMRGRLYYTAKAKKTG-KVMIKTHPCSRLCFCK-CWTCFKEVDAEQYYSELEEQLTDEFNAELNRVQLKRLDLIFVTFQDARTVRRIYDDYKYIHCGR--------------------HPKQSSVTTIVKNYHWRVAHAPHPKDIIWKHLSIRRFSWWTRFIAINTFLFFLFFFLTTPAIIINTIDIYN----------VTRPIEKLQSPIVTQFFPSVLLWAFTVTMPLLVYLSAFLEAHWTRSSQNLIIVHKCYIFLVFMVVILPSMGLTSLHVFLRWLFDIYYLEHATIRFQCVFLPDNGAFFINYVITAALLGTGMELMRLGSLCTYCTRLFLSKSEPERVHIRKNQATDFQFGREYAWMLNVFSVVMAYSITCPIIVPFGLLYLCMKHITDRYNMYYSYAPTKLNAQIHM-AAVYQAIFAPLLGLFWMLFFSILRVGSL----HSITLFSMSSLIISVVIAFSGVFLGKLRIAQRYEQPEEETETVFDVEPSSTTSTPTSLLYVATVLQE-------------PELNLTPASSPARHTYGTINSQPEEGEEESGLRGFARELDSAQFQEGLEMEGQSH---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NP91-1", "uniprot_id": "TM63_DROME", "id": "Q6NP91-1", "name": "Mechanosensitive cation channel Tmem63", "aln": "MVMSENS-----------------------NISYCQAVANRTSFFTTAYNGIPETLILNTIFWVLLILLFTVLRHQAGDFGRLALVNSNGSKKRWTEIFYSRAASVVDPQPSTSTQVSPRPSTTSQGVPDSTPLSPIQPEEGLFGWIRVTLKLRKETILLHTGPDAVHYLSFQQHLMAVMALVTIVSLVIILPVNFLNGPKENPYDVNAFGRTTMANLSPDSPWLWVHTIITILYIPLVVLIMRRASGRNAFKK--AATRTIMISNISSSDRNKTVVRNYMQELFPDVTIENVSIAYNISRLYVRNAEFERVHEARLYCEHHRNRDT--LMVKPEMCS-----------CKKENAYEYYQREERKLSGDVARLRASTMNEPLDIAFITVSTVQEAQNIVTHFTPGTYRQ-----------------------------------WHLVFAPSPDDLFWENLNVNKSHWYLKFFCVNAVLFLVLFFLSTPAMVVSLLNSRP----------WVKETEGKISPLVADFLPTLMLWTLSALMPVIVAISDKWMRHYTRSKQNYSIMTKCFGYLLMMIMILPSLGLTSAQALLEWGFLNQTD-----RWQCIFLPDRGSFYVNYIITAAFIGTALELLRFPELIVYIWSLLKAKSKAETPYIRKAILIEFPFGTHYAWTTLVFTIAIVYSVACPLIMPFAMIYICLKHFVDRHNLYFAYGPSNMISRKGG-KIHSTAVTMTKFSVVILVLVMAMICFFR----GDNGMARFLLLIISLAITLTLFTFMSPIKRCAATRRPSIVEIAGPAP-----------IYVPDVLKD-------------NGIRTSSVRPSAAAFGGYGS------DSVSEYDSSQYSVNSVEA--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03516-1", "uniprot_id": "RSN1_YEAST", "id": "Q03516-1", "name": "Uncharacterized protein RSN1", "aln": "-----------------------------MNSTNSTNSTTTATSTNTSTQQVVTSLVSNGTIFGVFVIAFLILRIKLKRIY-------------EPKSSFN---------------------------LINEEKKPEPLPQGVWQWLKPLLKKSDNFVIQQAGLDGYFFLRYLFIIAIYCAVSMSYIFPILLSINASNGNHESGLNQLAYQNVKHRGRYFAHVFCGWIFFWGFLYIIYRELYFYTSMKQAVLASPRYAKKLSSRTVLFQTVPKQYLSEEEFSKLFDGVKRVWIARGSGSIEAMVKARDNMAIQLEGAETKYLKAALKKIKKLN-KKSPQLSVSDNIAEYVPDKKRPHHKINKVAKFFFGKKVDTISYIKEELPKLNQKVKALQEDHENSSPFNSVFVEFES--------------QYQAQVAAQITTYHAPLFMTPVYIGIEPSDVVWFNLRMFWWERLGREVSAVSAIVALVILWAFPVAFVGMISNITSLTNEVKWLKFIYKLPKQLLGLLTSLAPTVALAVLMSFLPKFIRGMAITQGAPSKQNVEYFTQQAYFAFQVIQVFLVTTLSSAATSTVTEIVKEPTKA----MDLLASNLPKASNFFMSYVILQGLSISSGALLQIVPLILFYVLGAFLDGTVRKKWNRFCGLSSMQWGTAFPVYTNLAVITFSYSIISPLILLFAAVAFFLLYIAYLYNLTYVYQESPDARGIYYPRALFQTIVGIYIGQICLLGLFAVGKGWGPIVLQVIGICVTVLIHLHLSAAFDHLSKVIPVDTMKPLDGVSDTPSFKNIYKGIESTKVKKNTFGANIDMDGIKELPEFPIKKYHKRSESVTEQQVENSIFSENTFEYQFNPANEANADGHAINAENLIEDVPLLADGDTMKIPPAPWWKRFLKPHIYYSYKAVKSRLPEIYGLVDPDERVNDFDISHAYDYPAVSAQCPELWIPRDPFGFSKLLISDVSGVVEMNDENATIDENLKFTLRDVPPPYNDVKDEANGEANGEFDTASKENNPFADPKYKEEESRSAV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *: : : ..: : .:* . . . * *: . . : * *. :: : : : . ::*.:* . : : ... . . .:*: : . . : . : . : : . . : :: . . . . : . * .. :. : . * :: * :* : : . :. :.:: : * .:. :. :::.: *:: * : :* :: ::. : : : :: :.::.::. :: . . . *.. . *::.*:* .: :. *::: * : . : . :* : : : : **: .*:*: *. : : : ::. :*: : * : :: : . : . : : : : : : . : . : : : . ", "identical_positions": 31, "similar_positions": 173, "identity": "2.98%" }, { "cls_id": "homologset.agr.SGD:S000004880", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q15181-1", "uniprot_id": "IPYR_HUMAN", "id": "Q15181-1", "name": "Inorganic pyrophosphatase", "aln": "------------------------------------------------MSGFSTEERAAPFSLEYRVFLKNEKGQYISPFHDIPIYADK----------------------DVFHMVVEVPRWSNAKMEIATKDPLNPIKQDVKKGKLRYVANLFPYKGYIWNYGAIPQTWEDPGHNDKHTGC----CGDNDPIDVCEIGSKVCARGEIIGVKVLGILAMIDEGETDWKVIAINVDDPDAANYNDINDVKRLKPGYLEATVDWFRRYKVPDGKPENEFAFNAEFKDKDFAIDIIKSTHDHWKALVTKKTNGKGISCMNTTLSESPFKCDPDAARAIVDALPPPCESACTVPTDVDKWFHHQKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D819-1", "uniprot_id": "IPYR_MOUSE", "id": "Q9D819-1", "name": "Inorganic pyrophosphatase", "aln": "------------------------------------------------MSGFSSEERAAPFTLEYRVFLKNEKGQYISPFHDVPIYADK----------------------DVFHMVVEVPRWSNAKMEIATKDPLNPIKQDVKKGKLRYVANLFPYKGYIWNYGAIPQTWEDPGHSDKHTGC----CGDNDPIDVCEIGSKVCARGEIIRVKVLGILAMIDEGETDWKVIAINVDDPDAANYKDISDVERLKPGYLEATVDWFRRYKVPDGKPENEFAFNAEFKNKDFAVDIIKSTHDYWKALVTKKTDGKGISCMNTTVSESPFKCDPDAAKAIVDALPPPCESACSLPTDVDKWFHQQKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AI23-1", "uniprot_id": "A0A8I6AI23_RAT", "id": "A0A8I6AI23-1", "name": "inorganic diphosphatase", "aln": "------------------------------------------------MSSFSSEERAAPFTLEYRVFIKNEKGQYISPFHDVPIYADKMTNAFSTLKDQQQVWQSQESLADVFHMVVEVPRWSNAKMEVR---------EVVRLG------ILVIFINYFYLICLCGSTWEDPGHSDEHTGC----CGDNDPIDVCEIGSKVCARGEIIRVKVLGILAMIDEGETDWKVIAINVDDPDAANYHDISDVERLKPGYLEATVDWFRRYKVPDGKPENEFAFNAEFKNKEFAVDIIKNTHDYWKALVTKKTDGKGISCMNTTVSESPFKCDPDAAKAIVDAVSNWCAS--VVCTCLHTWPLS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H2U2-1", "uniprot_id": "IPYR2_HUMAN", "id": "Q9H2U2-1", "name": "Inorganic pyrophosphatase 2, mitochondrial", "aln": "------------MSALLRLL-----RTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYISPFHDIPLKVNSKEENGIPMKKARN-----DEYENLFNMIVEIPRWTNAKMEIATKEPMNPIKQYVKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNC----FGDNDPIDVCEIGSKILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESVSS-SPNK-ESNEEEQVWHFLGK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91VM9-1", "uniprot_id": "IPYR2_MOUSE", "id": "Q91VM9-1", "name": "Inorganic pyrophosphatase 2, mitochondrial", "aln": "------------MRALLPLL-----SVGR----GWRVGAAARP-PRRVMSLYRTEELGHPRSQDYRLFFKHVAGHYISPFHDIPLKADCKEEHDIPRKKARN-----DEYENLFNMVVEIPRWTNAKMEIATEEPLNPIKQDIKNGKLRYTPNIFPHKGYIWNYGALPQTWEDPHLRDKSTDC----CGDNDPIDVCEIGSKVLSRGDVVHVKILGTLALIDQSETDWKIIAINVNDPEAEKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENKFAFNGEFKNKAFALDVINSAHERWKEMVMKKCDKGAISCVNVHICDSPFHCTMEEARSLVESVPTPSMNK-ESNVEEEVWHFLRN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O77460-1", "uniprot_id": "IPYR_DROME", "id": "O77460-1", "name": "Inorganic pyrophosphatase", "aln": "MLAKITRSSFYASRAVGRLSGSIPTSPAALASNCRYIQIERKRTKSHEMALYETVEKGAKNSPSYSLYFKNKCGNVISPMHDIPLYANEEK--------------------TIYNMVVEVPRWTNAKMEISLKTPMNPIKQDIKKGKLRFVANCFPHKGYIWNYGALPQTWENPDHIEPSTGC----KGDNDPIDVIEIGYRVAKRGDVLKVKVLGTIALIDEGETDWKIIAIDVNDPLASKVNDIADVDQYFPGLLRATVEWFKIYKIPDGKPENQFAFNGDAKNADFANTIIAETHKFWQNLVHQSPASGSISTTNITNRNSEHVIPKEEAEKILAEAPDGGQVE-EVSDTVDTWHFIHLK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28239-1", "uniprot_id": "IPYR2_YEAST", "id": "P28239-1", "name": "Inorganic pyrophosphatase, mitochondrial", "aln": "-------------MNLLRMN-----ALTSKARSIERLKQTLNILSIRNHRQFSTIQQGSKYTLGFKKYLTLLNGEVGSFFHDVPLDLNEHE--------------------KTVNMIVEVPRWTTGKFEISKELRFNPIVQDTKNGKLRFVNNIFPYHGYIHNYGAIPQTWEDPTIEHKLGKCDVALKGDNDPLDCCEIGSDVLEMGSIKKVKVLGSLALIDDGELDWKVIVIDVNDPLSSKIDDLEKIEEYFPGILDTTREWFRKYKVPAGKPLNSFAFHEQYQNSNKTIQTIKKCHNSWKNLISGSLQEKYDNLPNTERAGN--------GVTLEDSVKPPSQIP----PEVQKWYYV---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . : : ::. *. * :**:*: : :*:**:***:..*:*: : : * . . .*: .***:* . * *****:* *** : *.: **:** :*:**:.* ***:*.*:.:** : : .*: .:.. ** * :* :**: **:* *** *.***: : :: : * . *. *: :: . . * . . : . * ", "identical_positions": 67, "similar_positions": 74, "identity": "18.46%" }, { "cls_id": "homologset.agr.SGD:S000004882", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q566R3-1", "uniprot_id": "GPTC4_RAT", "id": "Q566R3-1", "name": "G patch domain-containing protein 4", "aln": "MSVTPEVKSRGMKFAEEQLLKHGWTQGKGLGRKENGITQALKVTLKQDTHGVGHDPAKEFTDHWWSDLFNKTAANLVVDSGKDGVQIRR--------LSKETTQRSHSKPSLLYQKFVKTATLTSGEEKPD------RDLESCSDVDNR--EPIPPKILTDEMLLKACEGRTAHKAARIGITMKAKLARLEAQEQAFLARLKGSKDVGTSQPLTDSEPSQKKKKRRKQKEEEEAATTEKS-LGEELLEHTDKSFRKSKKKKKKKK-----DEREGTAIGSEEEEAAGVCGPAELST-EQSDQSSRKKKKRRRRHHEEEEEMGVCDEGGR--DVTG--GPKAVNSGADTDPWRSSKKRQ-TCEEDLDTQDEEDKDDLTKKERKVR---------KKDKKKRQQYCEEV--LDVSNKDDGRTWEAED---------GGERSQPHPK---------ARAKKKKRKTD--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TFK5-1", "uniprot_id": "GPTC4_MOUSE", "id": "Q3TFK5-1", "name": "G patch domain-containing protein 4", "aln": "MSVTPEVKSRGMKFAEEQLLKHGWTQGKGLGRRENGITQALKVTLKQDNHGVGHDPAKEFTDHWWSDLFNKTAASLVVDSGKDGVQIRR--------LSKETTQRSHPKPSLLYQKFVKTATLTSGEEKPD------RDLGNCSDVDNH--EPTPPKILTDEMLLKACEGRTAHKAARIGITMKAKLARLEAQEQAFLAQLKGSKALGTSQPLTDSEPSQKKKKKRKQKEGEEAATTEKS-LGDELLGHTDRSFRDSRKKKKRQK-----AERQGTAIGSEEEEAAGESGPRELST-EQSDQPSRKKKKRRKQRHEEDGEMGVCDEGGR--DVTS--RPKAVNSGGDKDPRRSSKKRG-TCGEDLDTQEEEGKDDLTKGERKVR---------RKDKRKRQQCCEED--LDVSSKDDGGTWVAED---------AGERSRQYPK---------ERAKKKKRKRDRGSEVDLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T3I0-1", "uniprot_id": "GPTC4_HUMAN", "id": "Q5T3I0-1", "name": "G patch domain-containing protein 4", "aln": "MNVTPEVKSRGMKFAEEQLLKHGWTQGKGLGRKENGITQALRVTLKQDTHGVGHDPAKEFTNHWWNELFNKTAANLVVETGQDGVQIRS--------LSKETTRYNHPKPNLLYQKFVKMATLTSGGEKPN------KDLESCSDDDNQ--GSKSPKILTDEMLLQACEGRTAHKAARLGITMKAKLARLEAQEQAFLARLKG-QDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEE-KMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETVLGGGTREAESRACSDGRSRKSKKKRQQHQEEEDILDVRDEKDGGAREAESRAHTGSSSRGKRKRQQHPKKERAGVSTVQKAKKKQKKRD--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9NZA1-1", "uniprot_id": "A0A8M9NZA1_DANRE", "id": "A0A8M9NZA1-1", "name": "G patch domain-containing protein 4", "aln": "MAETVQEKSTGLKFAEEQLLRHGWEKGKGLGRAENGISEAIKVKVKCDKGGMGHKQGEQFSFHWWDHVFNKASSGLVVESGQNGVMVKKSDDSSDGLISNKKPRKAQQAKSMLYGCFVKSATLLSGEEQPEKISDAEDDSSSSSEDEDQKLDLSTTTKLSDADLLKACGGRTAHKGARHGLTMSAKLARLEQQEQEFINKYGKKKHTAETSTNNTEHLNTERHSEGKEKTKRKKSKKKEEVLEED---NSHDTVEDDKSKKSKVS----DAASVSDDMTENTKQKKKKRKHKEKAPQDCPNHCSEDVNEEAEPKSEESERFLPINESME--------KKKKKKKRSKVAPETADEASEDHIEAHGELPLEGSTEHQLASELPSKR--------KKKKRNFEQLEASENSVDVTEDTNNEALIMDTQEN---SRRKNKKKKRGKNKELENVEDVMEAVPKKKSKE--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V9Z8-1", "uniprot_id": "Q9V9Z8_DROME", "id": "Q9V9Z8-1", "name": "G patch domain-containing protein 4", "aln": "-----------MDFAKKILGKYGWKEGDGLGKNNTGIAVPLKAALKFDNAGLGVDRAQEFNDHWWERCFNEAASNVDVQIQQDGQVSTSRRKGEEAVEISTRGFSARKLKKAKEQHASDGKATYDNFLQTSLLTQSGGEVETSERIRVEDIEVTKVAVLTDAELFKACGGRTAHKGARHGLKLSGKIARLEQQEREMLEKLQRKLKTTPETEHRAVESVDDSVEQCDTKAKKKKKSIAEEFSEACEVSQLEEPIKSKKKKK-------------------DKAEKAGKESPAHQTPEDPVKIKRKKNKTRE---------------------------PGEEDGVEVEEPVKIKKKKDKRADRQAGLGATEGLPQDVETDEQVKS--------KKKRKTADSSEESETSTKLKKKRKNKENV--------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03525-1", "uniprot_id": "TMA23_YEAST", "id": "Q03525-1", "name": "Protein TMA23", "aln": "------------MDSKEYLISYGWKEGEAFR--EGGLKRPILVKHKRDKKGLGNAPGGNDGEAWWERLFDGHLKNLDVSTDSNNGSIKFT-------QNEAVATAVSKSSSPLYRWFVKGEGLKG--------------------------TITNLGKKEEASFVVSSASSSKGKKRRR---------RDEDDNKVKRKKLKKDKKTSNDSE-------SKKKKKKKSKKESKKGKKSKHSSDEGDKSKHKKSKKSKKHKK---------------------EESSARRDRKEHI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: * :** :*..: : *: .: . * *. *:* . : **. *: .: *. .:. . . . . : :. :. . : * * * * ::: : . .. * : . : . ...: ** : . ", "identical_positions": 20, "similar_positions": 53, "identity": "4.24%" }, { "cls_id": "homologset.agr.SGD:S000004885", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2LAM0-1", "uniprot_id": "FA2H_RAT", "id": "Q2LAM0-1", "name": "Fatty acid 2-hydroxylase", "aln": "MAPAPPPAAS---FTSAEVQRRLAAGACWVRRGAS-LYDLTGFVRHHPGGEQLLLARAGQDISADLDGP-PHKHSDNARRWLEQYYVG-------ELRADPQDPTENGAGAP--------------AETQKTDAAIEPQFKVVDWDKDLVDWQKPLLWQVG---HLGEKYDEWVHQP--VARPIRLFHSDLIEAFSKTVWYSVPIIWVPLVLYLSWSYYRTLTQDNIRLFASFTRDYSLVVPESVFIGLFVLGMLIWTLVEYLIHRFLFHMKPPS-NSHYLIMLHFVMHGQHHKAPFDGSRLVFPPVPASVVVAFFYVFLRLILPEAVAGILFAGGLLGYVLYDMTHYYLHFGSPHKGSYLYNMKAHHVKHHFEYQKSGFGISTKLWDYFFHTLIPEEADPKMQ---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5MPP0-1", "uniprot_id": "FA2H_MOUSE", "id": "Q5MPP0-1", "name": "Fatty acid 2-hydroxylase", "aln": "MAPAPPPAAS---FTPAEVQRRLAAGACWVRRGAS-LYDLTSFVRHHPGGEQLLLARAGQDISADLDGP-PHRHSDNARRWLEQYYVG-------ELRADPQDPTENGAVAS--------------AETQKTDPALEPQFKVVDWDKDLVDWQKPLLWQVG---HLGEKYDEWVHQP--VARPIRLFHSDLIEAFSKTVWYSVPIIWVPLVLYLSWSYYRTLTQDNIRLFASLTREYSMMMPESVFIGLFVLGMLFWTFVEYVIHRFLFHMKPPS-NSHYLIMLHFVMHGQHHKAPFDGSRLVFPPVPASLVIAFFYVFLRLILPETVGGIIFAGGLLGYVLYDMTHYYLHFGSPHKGSYLYNMKAHHVKHHFEYQKSGFGISTKLWDYFFHTLIPEEAHPKMQ---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L5A8-1", "uniprot_id": "FA2H_HUMAN", "id": "Q7L5A8-1", "name": "Fatty acid 2-hydroxylase", "aln": "MAPAPPPAAS---FSPSEVQRRLAAGACWVRRGAR-LYDLSSFVRHHPGGEQLLRARAGQDISADLDGP-PHRHSANARRWLEQYYVG-------ELRGEQQGSMENEPVAL--------------EETQKTDPAMEPRFKVVDWDKDLVDWRKPLLWQVG---HLGEKYDEWVHQP--VTRPIRLFHSDLIEGLSKTVWYSVPIIWVPLVLYLSWSYYRTFAQGNVRLFTSFTTEYTVAVPKSMFPGLFMLGTFLWSLIEYLIHRFLFHMKPPS-DSYYLIMLHFVMHGQHHKAPFDGSRLVFPPVPASLVIGVFYLCMQLILPEAVGGTVFAGGLLGYVLYDMTHYYLHFGSPHKGSYLYSLKAHHVKHHFAHQKSGFGISTKLWDYCFHTLTPEKPHLKTQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13ABP4-1", "uniprot_id": "A0AB13ABP4_DANRE", "id": "A0AB13ABP4-1", "name": "Fatty acid 2-hydroxylase", "aln": "MSTKMSPSLSPRFFSEKEVAKHCTKDSCWVLLGTR-VYDVTAFLRMHPGGEALILRRSGKDISLEIEGP-PHRHSENARRWMEQYYIG-------ELDRDSTDEDTEETLRQRKK-----IPESITEEEEETTSAIN-KCSKVDEETDLVDWRKPLAWQVG---HLGEKYDTWVHQP--VDRPIRLFGNDFFEANTKTSWYMVPIVWMPLVIYLSWYCYSLLAQETTRLVIS--SDYSILVHKYSFPFIFALGMFLWSFIEYCIHRFVFHMRPPA-HNYYLITLHFLLHGQHHKSPFDGSRLVFPPSLAAVVIGLFYLTLQQLLVEGLGTSLFVGGLCGYVVYDMIHYYLHYGSPSKGSYLYGLKAYHVKHHFEHQRAGFGITTTFWDHPFKTVIPEQTF-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03529-1", "uniprot_id": "SCS7_YEAST", "id": "Q03529-1", "name": "Ceramide very long chain fatty acid hydroxylase SCS7", "aln": "MSTNTSKTLEL--FSKKTVQEHNTANDCWVTYQNRKIYDVTRFLSEHPGGDESILDYAGKDITEIMKDSDVHEHSDSAYEILEDEYLIGYLATDEEAARLLTNKNHKVEVQLSADGTEFDSTTFVKELPAEEKLSIATDYSNDYKKHKFLDLNRPLLMQILRSDFKKDFYVDQIHRPRHYGKGSAPLFGNFLEPLTKTAWWVVPVAWLPVVVYHMGVALKNMN-------------------QLFACFLFCVGVFVWTLIEYGLHRFLFHFDDWLPESNIAFATHFLLHGCHHYLPMDKYRLVMPPTLFVILCAPFYKLVFALLPLYWAYAGFAGGLFGYVCYDECHFFLHHSKLP--PFMRKLKKYHLEHHYKNYQLGFGVTSWFWDEVFGTYLGPDAPLSKMKYE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:. . : . *: * .: : . *** :**:: *: ****: : :*:**: :... *.** .* . :*: *: * . : : :: . . .::* .:** *: . : * :*:* : : .:::* :** *: **: *:*:*:* : : :* :* :.*:::** :***:**: .. : **::** ** *:* ***:** :: . ** : :* . *.*** *** ** *::**... .:: :* :*::**: : ***::: :** * * .. ", "identical_positions": 89, "similar_positions": 104, "identity": "21.87%" }, { "cls_id": "homologset.agr.SGD:S000004887", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P57791-1", "uniprot_id": "FACE2_MOUSE", "id": "P57791-1", "name": "CAAX prenyl protease 2", "aln": "MAALGGDGLRLLSVSRPERQPESAALSGPGSGLCCWVSVFSCFSLACSYVGSLYVWKS--ELPRDHPAVIKRRSTSVLVVSSLSPLCVLLWRELTGIQPGTS--LLTLMGFRLEG----------IFPAALLPLLLTMILFLGPLMQLSMDCPCDLTDGLKVVLAPRSWARCLTDMRWLRNQVIAPLTEELVFRACMLP----MLAPCTGLGPAVFTCP-LFFGVAHFHHIIEQLRFRQSSVGSIFVSAAFQFSYTAVFGAYTAFLFIRT-GHLIGPVLCHSFCNYMGFPAVCAALEHP--QKWPLLAGYALGVGLFLLLLQPLTDPKLYGSLPLCMLLERTGASETLLCS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0BMW8-1", "uniprot_id": "FACE2_RAT", "id": "B0BMW8-1", "name": "CAAX prenyl protease 2", "aln": "MAALGGDGLRLLSVSRPERQPESAALSSPGPGLCCWVSVFSCFSLACSYVGSLYVWKS--ELPRDHPAVIKRRFTSVLVVSSLSPLCVLLWRELTGIQPGTS--LLTLMGFRLEG----------IFPAALLPLLLTMILFLGPLMQLCMDCPCDLTDGLKVVLAPRSWARRLTDMRWLRNQVIAPLTEELVFRACMLP----MLAPCTGLGPAVFTCP-LFFGVAHFHHIIEQLRFRQSSVGSIFLSA----------------------GHLIGPVLCHSFCNYMGFPAVCAALEHP--QKWPLLAGYALGVGLFLLLLQPLTDPKLYGSLPLCMLLERTGASETLLCS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y256-1", "uniprot_id": "FACE2_HUMAN", "id": "Q9Y256-1", "name": "CAAX prenyl protease 2", "aln": "MAALGGDGLRLLSVSRPERPPESAALGGLGPGLCCWVSVFSCLSLACSYVGSLYVWKS--ELPRDHPAVIKRRFTSVLVVSSLSPLCVLLWRELTGIQPGTS--LLTLMGFRLEG----------IFPAALLPLLLTMILFLGPLMQLSMDCPCDLADGLKVVLAPRSWARCLTDMRWLRNQVIAPLTEELVFRACMLP----MLAPCMGLGPAVFTCP-LFFGVAHFHHIIEQLRFRQSSVGNIFLSAAFQFSYTAVFGAYTAFLFIRT-GHLIGPVLCHSFCNYMGFPAVCAALEHP--QRRPLLAGYALGVGLFLLLLQPLTDPKLYGSLPLCVLLERAGDSEAPLCS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA70QJR3-1", "uniprot_id": "A0AA70QJR3_DANRE", "id": "A0AA70QJR3-1", "name": "CAAX prenyl protease 2", "aln": "----------MLSIKT-----LSDTFVG-----ECWISVSCCLLLACLYVGSLYVWKG--SLPRDHPNTIKRRFTSVLCVSAVAPLVVLAWTHSMKLRPSPP--LWALLGIRLEG----------FVPAAVLPLTLTMVLFLGPLTQLAVESPRGLFHDVKAGLNCQSWSKRVKDLKWLRNHVVAPLTEEFVFRACIIP----MLVPCTGPTSAIFISP-LFFGVAHFHHIIEQLRFGQDTVFDILICAAFQFTYTSVFGVYTAFIFIRT-GHLVGPVLCHSFCNRMGFPAIGSVLEHP--QKSLILLFYQLGVLLFFILLFPFTDPTFYGMSPVCSLLLTPRSACT----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9U1H8-1", "uniprot_id": "FACE2_DROME", "id": "Q9U1H8-1", "name": "CAAX prenyl protease 2", "aln": "--------MKNLSETEAEVTMQENVVHESLPQIPVATSVSCCFVLAVLYVGSLYIWST--KHNRDHPTTVKRRFASVSMVMLAAPFFVYFFSSPE-LLSRVP--FPKLLGLRLEG----------LWQAVVIPYSLTVLLFLGPIFVNMQN------ESVRSYFDLDYWRGSFGSIIWVRNHVIAPLSEEFVFRACMMP----LILQSFSPLVAVFITP-LFFGVAHLHHIAERLSLG-VELSTALLIGLFQFIYTTLFGFYSAFLFART-GHVMAPILVHAFCNHMGLPDLQDLWQQDLWRRVVAIILYLAGFVGWMFLVPLATDPSIYDNTLYWNA-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03530-1", "uniprot_id": "RCE1_YEAST", "id": "Q03530-1", "name": "CAAX prenyl protease 2", "aln": "--------------------------------MLQFSTFLVLLYISISYVLPLYATSQPEGSKRDNPRTIKSRMQKLTIMLISNLFLVPFLQSQLSSTTSHISFKDAFLGLGIIPGYYAALPNPWQFSQFVKDLTKCVAMLLTLYCGPVLDFVLYHLLNPKSSILEDFYHEFLN-IWSFRNFIFAPITEEIFYTSMLLTTYLNLIPHSQLSYQQLFWQPSLFFGLAHAHHAYEQLQEGSMTTVSILLTTCFQILYTTLFGGLTKFVFVRTGGNLWCCIILHALCNIMGFPGPSRLNLHFTVVDKKAGRISKLVSIWNKCYFALLVLGLISLKDTLQTLVGTPGYRITL---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : :: ** .** . **:* .:* * .: : : * . ::*: : : : ::* : . : : : . : .** :.**::**:.: : ::. :: . :* * ****:** ** *:* :: *:: :: *::** **:* : . . : ", "identical_positions": 37, "similar_positions": 61, "identity": "10.54%" }, { "cls_id": "homologset.agr.SGD:S000004889", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R317-1", "uniprot_id": "UBQL1_MOUSE", "id": "Q8R317-1", "name": "Ubiquilin-1", "aln": "-----------------------MAESAESGGPPG-AQDSAADGG---------PAEPKIMKVTVKTPKEKEEFAVPENSSVQQFKEEISKRFKSHIDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQNRPQDNS-AQQTNAPGSTVTS--------------SPAPDSNPTSGSAAN---------SSFG-----------VGGLGGLAGLSSLGLNTTNFSELQS---QMQRQLLSNPEMMVQIMENPFVQS----MLSNPDLMRQLIMANPQMQQLIQRNPEISHMLNNPDIMRQTLELARNPAMMQEMMRNQDRALSN-----------LESIPGGYNALRRMYTDIQEPMLNA--AQEQFGGNPFASLVSSSSSAEGTQPSR-TENRDPLPNPWAPQTSQSSPASGT--------------------------------------------------TGSTTNTMSTSGGTATSTPAGQSTSGPSLVPG-AGASMFNTPGMQSLLQQITENPQLMQNMLS-----------APYMRSMLQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQNPDT--------------------LSAMSNPRAMQALLQIQQGLQTLATEAPGLIPGF-TPGL----------------AAGNSG-----------GSSGTNAPSTAPSED---------------TNPQGGTAEPG-HQQFIQQMLQALAGVN---PQLQSPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIERLLGS-QPS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JJP9-1", "uniprot_id": "UBQL1_RAT", "id": "Q9JJP9-1", "name": "Ubiquilin-1", "aln": "-----------------------MAESAESGGPPG-AQDSAADSG---------PAEPKIMKVTVKTPKEKEEFAVPENSSVQQFKEEISKRFKSHIDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQNRPQDNS-AQQTNTTGNSVTS--------------SPAPDSNPTSGPAAN---------SSFG-----------LGGLGGLAGLSSLGLNTTNFSELQS---QMQRQLLSNPEMMVQIMENPFVQS----MLSNPDLMRQLIMANPQMQQLIQRNPEISHMLNNPNIMRQTLELARNPAMMQEMMRNQERDLSN-----------LESIPGGYNALRRMYTDIQEPMLNA--AQEQFGGNPFASLVSSPSSAEGTQPSR-TENRDPLPNPWAPQTPQSSPASGS--------------------------------------------------TGSTTNTVSTSAGNATSTPAGQGTSGPNLVPG-AGASMFNTPGMQSLLQQITENPQLMQNMLS-----------APYMRSMMQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQNPDT--------------------LSAMSNPRAMQALLQIQQGLQTLATEAPGLIPGF-TPGL----------------AAGNSG-----------GPAGTTAPSTAPGED---------------TNPQGGAAEPG-HQQFIQQMLQALAGVN---PQLQSPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIERLLGS-QPS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UMX0-1", "uniprot_id": "UBQL1_HUMAN", "id": "Q9UMX0-1", "name": "Ubiquilin-1", "aln": "-----------------------MAESGESGGPPG-SQDSAAGAEGAGAPAAAASAEPKIMKVTVKTPKEKEEFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQNRPQDHS-AQQTNTAGSNVTT--------------SSTPNSNSTSGSATS---------NPFG-----------LGGLGGLAGLSSLGLNTTNFSELQS---QMQRQLLSNPEMMVQIMENPFVQS----MLSNPDLMRQLIMANPQMQQLIQRNPEISHMLNNPDIMRQTLELARNPAMMQEMMRNQDRALSN-----------LESIPGGYNALRRMYTDIQEPMLSA--AQEQFGGNPFASLVSNTSSGEGSQPSR-TENRDPLPNPWAPQTSQSSSASSG--------------------------------------------------TASTVG--GTTGSTASGT-SGQSTTAPNLVPG-VGASMFNTPGMQSLLQQITENPQLMQNMLS-----------APYMRSMMQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQNPDT--------------------LSAMSNPRAMQALLQIQQGLQTLATEAPGLIPGF-TPGLG---------------ALGSTG-----------GSSGTNGSNATPSEN---------------TSPTAGTTEPG-HQQFIQQMLQALAGVN---PQLQNPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIERLLGS-QPS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QZM0-1", "uniprot_id": "UBQL2_MOUSE", "id": "Q9QZM0-1", "name": "Ubiquilin-2", "aln": "-----------------------MAENGESSGPPRPSRGPAAAPG-----AASPPAEPKIIKVTVKTPKEKEEFAVPENSTVQQFKEAISKRFKSQTDQLVLIFAGKILKDQDTLMQHGIHDGLTVHLVIKSQNRPQGQATTQPSTTAGTSTTTTTTTTAAAP-AATTSSAPRSSSTPTTTNS---------SSFG-----------LGSLSSLS---NLGLNSPNFTELQN---QMQQQLLASPEMMIQIMENPFVQS----MLSNPDLMRQLIMANPQMQQLIQRNPEISHLLNNPDIMRQTLEIARNPAMMQEMMRNQDLALSN-----------LESIPGGYNALRRMYTDIQEPMLNA--AQEQFGGNPFATVGSSSTSGEGTQPSR-TENRDPLPNPWAPPPTTQTAATTT--------------------------------------------------TTTTTSSGSGSGSSSSSTTAGNTMAAANYV-----ASIFSTPGMQSLLQQITENPQLIQNMLS-----------APYMRSMMQSLSQNPDMAAQMMLSSPLFTSNPQLQEQMRPQLPNFLQQMQNPET--------------------IAAMSNPRAMQALMQIQQGLQTLATEAPGLIPSF-APGVGMGVLGTAITPVGPVTPIGPIGPIVPFTPIGPIGPIGPTGPASSPGSTGTGIPPATTVSSSAPTETISPTSESGPNQQFIQQMVQALTGGSP--PQPPNPEVRFQQQLEQLNAMGFLNREANLQALIATGGDINAAIERLLGS-QPS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AA63-1", "uniprot_id": "D4AA63_RAT", "id": "D4AA63-1", "name": "", "aln": "-----------------------MAENGESSGPPRPSRGPAAAPG-----AANPPAEPKIIKVTVKTPKEKEEFAVPENSTVQQFKEAISKRFKSQTDQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIKSQNRPQGQATTQPSTTAGTSTTTTTTTTAAAPPAATTSSAPRCSTTATTTNS---------SNLG-----------LGSLASLG---NLGLNSSNFTELQN---QMQQQLLASPEMMIQIMENPFVQS----MLSNPDLMRQLIMANPQMQQLIQRNPEISHLLNNPDIMRQTLEIARNPAMMQEMMRNQDLALSN-----------LESIPGGYNALRRMYTDIQEPMLNA--AQEQFGGNPFATVGSSSSSGEGTQPSR-TENRDPLPNPWAPPPTTQTSATTT--------------------------------------------------TTTTSS-GTVAGSNTSSTTAGNTMAAANYV-----ASIFSTPGMQSLLQQITENPQLIQNMLS-----------APYMRSMMQSLSQNPDMAAQMMLSSPLFTANPQLQEQMRPQLPNFLQQMQSPET--------------------IAAMSNPRAMQALLQIQQGLQTLATEAPGLIPGF-TPGVGVGVLGTAITPVGPVTPIGPIGPIVPFTPIGPIGPIGPTGPASSPGSTGTGIPPATTVSSSAPTETISPTSESGPSQQFIQQMVQALTGGSP--PQPPNPEVRFQQQLEQLNAMGFLNREANLQALIATGGDINAAIERLLGS-QPS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UHD9-1", "uniprot_id": "UBQL2_HUMAN", "id": "Q9UHD9-1", "name": "Ubiquilin-2", "aln": "-----------------------MAENGESSGPPRPSRGPAAAQG-----SAAAPAEPKIIKVTVKTPKEKEEFAVPENSSVQQFKEAISKRFKSQTDQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIKSQNRPQGQS-TQPSNAAGTNTTS--------------ASTPRSNSTPISTNS---------NPFG-----------LGSLGGLAGLSSLGLSSTNFSELQS---QMQQQLMASPEMMIQIMENPFVQS----MLSNPDLMRQLIMANPQMQQLIQRNPEISHLLNNPDIMRQTLEIARNPAMMQEMMRNQDLALSN-----------LESIPGGYNALRRMYTDIQEPMLNA--AQEQFGGNPFASVGSSSSSGEGTQPSR-TENRDPLPNPWAPPPATQSSATTS--------------------------------------------------TTTSTG--SGSG-NSSSNATGNTVAAANYV-----ASIFSTPGMQSLLQQITENPQLIQNMLS-----------APYMRSMMQSLSQNPDLAAQMMLNSPLFTANPQLQEQMRPQLPAFLQQMQNPDT--------------------LSAMSNPRAMQALMQIQQGLQTLATEAPGLIPSF-TPGVGVGVLGTAIGPVGPVTPIGPIGPIVPFTPIGPIGPIGPTGPAAPPGSTGSGGPTGPTVSSAAPSETTSPTSESGPNQQFIQQMVQALAGANA--PQLPNPEVRFQQQLEQLNAMGFLNREANLQALIATGGDINAAIERLLGS-QPS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99NB8-1", "uniprot_id": "UBQL4_MOUSE", "id": "Q99NB8-1", "name": "Ubiquilin-4", "aln": "-----------------------MAEPSGAETRPQ-------------------------IRVTVKTPKDKEEIVICDQASVKEFKEEISRRFKAQQDQLVLIFAGKILKDGDTLSQHGIKDGLTVHLVIKTPQKAQDPVTAAASPPSTPDSASAPSTTPASPAAAPVQPCSSGNTTSDAGSG------GGPSPVAAEGPSSATASILSGFGGILGLGSLGLGSANFMELQQ---QMQRQLMSNPEMLSQIMENPLVQD----MMSNPDLMRHMIMANPQMQQLMERNPEISHMLNNPELMRQTMELARNPAMMQEMMRNQDRALSN-----------LESVPGGYNALRRMYTDIQEPMFTA--AREQFGNNPFSSLAGNSDNS-SSQPLR-TENREPLPNPWSPSPPTSQAPGSG--------------------------------------------------GEGTGG--SGTSQVHPTVSNPFGINAASLG-----SGMFNSPEMQALLQQISENPQLMQNVIS-----------APYMRTMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQLRLQLPVFLQQMQNPES--------------------LSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGTPR-------------TSVPLAG---------SNSGSSAEAPTSSPGVP----------------ATSPPSAGSNAQQQLMQQMIQLLSGSGN--SQVPMPEVRFQQQLEQLNSMGFINREANLQALIATGGDINAAIERLLGS-QLS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A3P1-1", "uniprot_id": "D4A3P1_RAT", "id": "D4A3P1-1", "name": "Ubiquilin-4", "aln": "-----------------------MAEPSGAETRPQ-------------------------IRVTVKTPKDKEEILICDQASVKEFKEEISRRFKAQQDQLVLIFAGKILKDGDTLNQHGIKDGLTVHLVIKTPQKAQDPVTTTASSPSTPDSASAPSTTPASP-AAPVQPCSSGNTTSDASSG------GGPSPVAAEGPSNATASILSGFGGILGLGSLGLGSANFMELQQ---QMQRQLMSNPEMLSQIMENPLVQD----MMSNPDLMRHMIMANPQMQQLMERNPEISHMLNNPELMRQTMELARNPAMMQEMMRNQDRALSN-----------LESVPGGYNALRRMYTDIQEPMFTA--AREQFGNNPFSSLAGNSDNS-SSQPLR-TENREPLPNPWSPSPPTSQAPGSG--------------------------------------------------GEGTGG--SGTSQVHPTVSNPFGINAASLG-----SGMFNSPEMQALLQQISENPQLMQNVIS-----------APYMRTMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQLRLQLPVFLQQMQNPES--------------------LSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGTPR-------------TSVPLAG---------SNSGSAAEAPTASPGTP----------------ATTPPSAGSNTQQQLMQQMIQLLSGSGN--SQVPVPEVRFQQQLEQLNSMGFVNREANLQALIATGGDINAAIERLLGS-QLS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NRR5-1", "uniprot_id": "UBQL4_HUMAN", "id": "Q9NRR5-1", "name": "Ubiquilin-4", "aln": "-----------------------MAEPSGAETRPP-------------------------IRVTVKTPKDKEEIVICDRASVKEFKEEISRRFKAQQDQLVLIFAGKILKDGDTLNQHGIKDGLTVHLVIKTPQKAQDPAAATASSPSTPDPASAPSTTPASP-ATPAQPSTSGSASSDAGSGSRRSSGGGPSPGAGEGSPSATASILSGFGGILGLGSLGLGSANFMELQQ---QMQRQLMSNPEMLSQIMENPLVQD----MMSNPDLMRHMIMANPQMQQLMERNPEISHMLNNPELMRQTMELARNPAMMQEMMRNQDRALSN-----------LESIPGGYNALRRMYTDIQEPMFSA--AREQFGNNPFSSLAGNSDSS-SSQPLR-TENREPLPNPWSPSPPTSQAPGSG--------------------------------------------------GEGTGG--SGTSQVHPTVSNPFGINAASLG-----SGMFNSPEMQALLQQISENPQLMQNVIS-----------APYMRSMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQLRLQLPVFLQQMQNPES--------------------LSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGISR-------------TPAPSAG---------SNAGSTPEAPTSSPATP----------------ATSSPTGASSAQQQLMQQMIQLLAGSGN--SQVQTPEVRFQQQLEQLNSMGFINREANLQALIATGGDINAAIERLLGS-QLS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWD9-1", "uniprot_id": "Q9VWD9_DROME", "id": "Q9VWD9-1", "name": "Ubiquilin-like protein", "aln": "-----------------------MAEGGSKR-----------------------------INVVVKTPKDKKTVEVDEDSGIKDFKILVAQKFEAEPEQLVLIFAGKIMKDTDTLQMHNIKDNLTVHLVIKAPTRNNEQPARQPADVRQT-------------------------------------------PFG-----------LNQFGGLAGMEALGAGSNTFMDLQA---RMQNELLNNGDMLRSLMDNPMVQQ----MMNNPDTMRQLITSNPQMHDLMQRNPEISHMLNNPDLLRQTMELARNPSMLQELMRSHDRAMSN-----------LESVPGGYSALQRIYRDIQEPMMNA--ATESFGRNPFAGLVDGGGSGAGNNPQQGTENRNPLPNPWG-------GANSG--------------------------------------------------TNGTVG---GSGAGNPTGDLPPNN-------------VLNTPAMRSLLQQMADNPAMMQNLLN-----------APYTRSMMESMSQDPDMAARLLSSSPLMSNNPALQEQVRQMMPQFMAQMQNPEV--------------------MNMLTNPDAMNAILQIQQGMEQLRSAAPGLVGTLGIPPPPPGAGTG-------TNPASGDG---------SGGNSGASTNNVSPSSGLN----------AGTGTPNLAPGGGPNAQLFNDFMMRMLNGMSNNADNTQPPEVRYQSQLEQLNAMGFVNRDANLQALIATFGDINAAVERLLSLNQLSLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8C5U9-1", "uniprot_id": "UBQL3_MOUSE", "id": "Q8C5U9-1", "name": "Ubiquilin-3", "aln": "-----------------------MAKSGEALPQGS----------------LAPAQDSQLIRVTVKTPKDKEDFSVVDTCTIRQLKEKISHRFKAHPNQLVLIFAGKILKDPDSLAQCGVRDGLTVHLVIKMQRRTIGTECPSPPVSIPGPNPG---------------EIPQSSSVYSVDGS---------PSFS--------------LGVLTGLSGLGLTSGSFSDQPG---SLMWQHISVPELVAQLVDDPFIQG----LLSNTGLVRQLVLDNPHMQHLIQQNPEIGHILNNPEIMRQTMEFLRNPSMMQEMMRSQDRALSN-----------LESIPGGYNVLRTMYTDIMDPMLNA--VQEQFGGNPFVTATTASTTTTSSQPSR-TENCDPLPNPWTSTYGVSGGRQGRGGRQSGDQDASENRNRLPSFLGNIGLFDYLQQLHETSQSLESYLQGTVPTSNPSQESPLSGNRVPPTLPSSPKSGSGQSLPK-ESVAIKGKSSCPAFLRHSTENSTGQGGSLHDAGKGST--GPSTSLPNLTSQIGDSANRSSFVSTPSSLMSATPGVPESPWLPPTGYSRSLRSAGTNQVPRIQNEIHQQLPLLLHLQTAMANPRVMQALLQIEQGLQILATEAPRLLLWFMPCLTGLN------------GVTGGTEA--------REGVVMSEDPRPTPTPQ---------------ISLAQGSTELGIHSSPFLQVLQALASTNP---QQLQLEAHFRVQLEQLRAMGFLNLEANLQALIATEGDVDAAVEKLRKS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7EYK8-1", "uniprot_id": "F7EYK8_RAT", "id": "F7EYK8-1", "name": "Ubiquilin-3", "aln": "MIFVSHPHPLSCVPTDLGLLLPIMAKSGEALPQGS----------------PAPVQDSQLIRVTVKTPKDKEDFSVVDTCTIRQLKEKISHRFKAHPNQLVLIFAGKILKDPDSLAQCGVRDGLTVHLVIKMQRRTTGTECPAPPVSTPGPNPL---------------ELPQPNSAYPVDGS---------PSFS--------------LGVLTGLSGLGLTSGSFSDQPG---SLMWQHMSVPELVAQLVDDPFIQG----LLSNTGLMRQLVLDNPHMQQLIQQNPEIGHILNNPEIMRQTMEFLRNPSMMQEMMRSQDRALSN-----------LESIPGGYNVLRTMYTDIMDPMLNA--VQEQFGGNPFATATTASTTTTSSQPSR-TENCDPLPNPWTSTCGVSGSRQGR---QPGDQDTSESRNRLPSFLGNIGLFDYLQQLHETSQALGSYLQGTVPTPSSSQETPLSGNRVPPNLPPSPKPGSGQPLPK-DSVAIKGKSSCPAFLRHSSENSTGQGGSLHDSGKSST--GPSTGLPNLTSQIGDNANRSPFVSTPSSLISPTPGAPESPWLPPTGYPRSLRSALTNQVPRMQNELHQQLPLLLHLQTAMTNPRVMQALLQIEQGLQILATEAPRLLLWFMPCLAGLS------------GVIGGTES--------REGVVMSEDPRPTPTSQ---------------ISLVQGSAELGFHSSPFLQVLQALASTNP---QQLQLEAHFRVQLEQLRAMGFLNLEANLQALIATGGDVDAAVEKLRKS------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H347-1", "uniprot_id": "UBQL3_HUMAN", "id": "Q9H347-1", "name": "Ubiquilin-3", "aln": "-----------------------MAKGGEALPQGS----------------PAPVQDPHLIKVTVKTPKDKEDFSVTDTCTIQQLKEEISQRFKAHPDQLVLIFAGKILKDPDSLAQCGVRDGLTVHLVIKRQHRAMGNECPAASVPTQGPSPG---------------SLPQPSSIYPADGP---------PAFS--------------LGLLTGLSRLGLAYRGFPDQPS---SLMRQHVSVPEFVTQLIDDPFIPG----LLSNTGLVRQLVLDNPHMQQLIQHNPEIGHILNNPEIMRQTLEFLRNPAMMQEMIRSQDRVLSN-----------LESIPGGYNVLCTMYTDIMDPMLNA--VQEQFGGNPFATATTDNATTTTSQPSR-MENCDPLPNPWTSTHGGSGSRQGR---QDGDQDAPDIRNRFPNFLGIIRLYDYLQQLHENPQSLGTYLQGTASALSQSQEPPPSVNRVPPSSPSSQEPGSGQPLPE-ESVAIKGRSSCPAFLRYPTENSTGQGGDQDGAGKSST--GHSTNLPDLVSGLGDSANRVPFAPLSFSPTAAIPGIPEPPWLPSPAYPRSLRPDGMNPAPQLQDEIQPQLPLLMHLQAAMANPRALQALRQIEQGLQVLATEAPRLLLWFMPCLAGTG------------SVAGGIES--------REDPLMSEDPLPNPPPE---------------VFPALDSAELGFLSPPFLHMLQDLVSTNP---QQLQPEAHFQVQLEQLRSMGFLNREANLQALIATGGDVDAAVEKLRQS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q14DL0-1", "uniprot_id": "UBQLN_MOUSE", "id": "Q14DL0-1", "name": "Ubiquilin-like protein", "aln": "-------------MPRIISRSPKMPQSRYTAGVPADGK-----------------ISPGVIRVIVKTPGNQIIFTVADDTLVRQFKEILSAHFKCQMEQLVLVFMGRLLKDHDTLSQRGITDGHIIHVVIKSKHGPRSLAHSFRNLVTNNPCHQ--------------DRNPKGNSS--------------------------------MVCQSAGMNETKVESSLLMEPEAPKVGTESPEVGSLEHIAQVLENLCVQS----LLSNMDFVHQMPPEQPYMEELIQQNPEVSHLLDNSEILCQTLELVRHLAIIQEIMQIQQPAQNPEYPPNSQPFLGLETVPNGNNHLGQSYVNNNDHMLNG--VPDLLEGNCFTALLDEQVLEQVQTPSLSQPLPQEQWDQLSSSQVIYANSCGLSSI---------------------------------------------TPTNATPNHTNNVSRENPAIVATQGQSNVCAVQQPAEIPVLPTISINQKP-QVDKDTTITLGISDQWLEEDLQQSDDQTSSQITGGMIQLLRNHPQMAAQMLLLMNTSQLNEQWRQETPTPLQSSQLHDL--------------------LLALANPKTSQALLQIEHGLQLLATEAPALLPYIEPYLWGLG----------------------------WLIPSICSYPDIVPWTWN------------VQDMAEPQCPESCHKSETVLQKVQPPSGDPS--HSLQAPEVRFSKEMECLQAMGFVNYNANLQALIATDGDTNAAIYKLKSSQGF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XIP4-1", "uniprot_id": "UBQLN_RAT", "id": "Q5XIP4-1", "name": "Ubiquilin-like protein", "aln": "-------------MPHIISRSPRMPQSRHPAGVPADGN-----------------IPPGVIRVIVKTPGNQNVFTVAEDTSVRQFKEQLSSHFKCQMEQLVLVSMGRLLKDHDTLSQRGITDGHTIHVVIKSKHGSRSLTHSFRNLLTNNPCHQ--------------DRNPKGNSS--------------------------------TVCQSAGMSETKVESSILMEPDASKVCTQDPEVGSPEQIEQMLETLCVQR----LLSNMFFMHQLPPEHPDMQDLIQQNPEVSHLLDNSEILCQTLELARHLAIIQEIMQIQQPAQNPEHTLNPQPYLGLETIPNGNIVLGQGYDNFNDHMLNGVHVHDLLEDDSFTALLAEQVLEQVQTPSLCQPPPQEQWGQLSSSQVIFANSCGFLT----------------------------------------------TPTEANLNTTNNASRENPAIAATQGQSNVCAVQQPTEIPSLCTIPVIQEPREGDKDTTIPQGSSAQWLEEDLQQSEEQSSSQITRSMIQLLRTHPHMAAEMLLLLNPPQLNEQWRQQTATPLQSSQLSDL--------------------LLALANPKTSQALLQIEHGLQLLATEAPALLPYIEPYLWGLG----------------------------WLIPSSCDYLDTVPWTWN------------VQDTVEPQCPESCHKSGTVLQREQPLSGDSS--HSLQAPEVRFSKEMECLQAMGFVNYNANLQALIATDGDTNAAIHKLKASQGF---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48510-1", "uniprot_id": "DSK2_YEAST", "id": "P48510-1", "name": "Ubiquitin domain-containing protein DSK2", "aln": "----------------------------------------------------------MSLNIHIKSGQDKWEVNVAPESTVLQFKEAINKANGIPVANQRLIYSGKILKDDQTVESYHIQDGHSVHLVKSQPKPQTASAAGANNATATGAAAG-------------TGATPNMSSGQSAG--------------------------FNPLADLTSARYAGYLNMPSADMFGPDGGALNNDSNNQDELLRMMENPIFQSQMNEMLSNPQMLDFMIQSNPQLQAMG---PQARQMLQSPMFR----QMLTNPDMIRQSMQFARMMDPN----------------AGMGSAGGAASAFPAPGGDAP----EEGSNTNTTSSSNTGNNAGTNAGT--------------------------------------------------------------------------------------------------------------------------------------------------------------NAGANTAANPFASLLNPALNPFANAGNAASTGMPAFD----------------------------------PALLASMFQPPVQASQAEDTRP--------------------------------------------------------------------------------------------------------------PEERYEHQLRQLNDMGFFDFDRNVAALRRSGGSVQGALDSLLNGDV----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: :*: :: . : : ::* : : *: *:::** ::: : *. :*:* . . : : : ::: . ::.* : : :* :. : *: ::*:.. : :: : :::: :: * . : . . . : . * :: * . * * :: ::. * ***.: : *: ** : *. :.*: * ", "identical_positions": 28, "similar_positions": 83, "identity": "3.49%" }, { "cls_id": "homologset.agr.SGD:S000004890", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K0J7-1", "uniprot_id": "A0A0G2K0J7_RAT", "id": "A0A0G2K0J7-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase", "aln": "MTQHAPRKWVRSERRVKPVSEREQQCRRRPRWAPRPERPVFSFLTSVVTVRAARWVTMEAPPLAGVPTECTPAVAGAEVRCPGPAPLRLLEWKVTAGATVRI-GSVLAVYEAAVSAQPAGPAPARAASGGCVRASRTERRLRSERAGVVRELCAQPGQVVAPG-ALLVRLEG-CSHPVVMKGLCAECGQDLTQLQSKNGKQQVPLSTATVSMVHSVPELMVSSEQAEKLGREDQQRLHRNRKLVLMVDLDQTLIHT-----------TEQHCPQMSNKGIFHFQLG---------------------RGEPMLHTRLRPHCKDFLEKIAKLYELHVFTFGSRLYAHTIAGFLDPEKKLFSHRILSRDECIDPFSKTGNLRNLFPCGDSMVCIIDDREDVWKFAPNLITVKKYVYFPGTGDVNAPPGARESQTRKKVNHSSKGADILEQALPVKDPEEGKP-PGVEQSNGLGKASRELNGGEAVP---GVFSSKTDEKETWSLTRASPASSSGGRELTEAPELPVSCEWDSRTAPGAHPTQGD-ATQGLDFDLSSDSESSESS-RSEGQKSFSSASDGENEERRRRKKSPATQDRTK-VPQHSGPHDTSGGRSAASPSGESGP-LHPHDKVSDPDTQEEGERDSLCGLGNGSVDRKEAETESQNSEQSGVTAGESLDQSVGEEEEEDTDDDDHLIHLEEILVRVHTDYYTKYDRYLNKELEEAPDIRKIVPELKSKVLADVAVIFSGLHPTNFPVEKTREHYHATALGAKVLTQLVLSPDAPDRATHLIAARAGTEKVRQAQEC-KHLHVVSPEWLWSCLERWDKVEEQLFPLMDEDTRTHRDNSPAVFPDRHSMLPTALFHPTPIHSKAHPGPEVRIYDSNTGKLIRMGTQGPAPALSSAPLIHGEPSSFRAVQPHQQQMFGEELPESQDGEQPGPARRKRQPSMSETMPLYTLCKEDLESMDKEVDDILGEGSDDSESEKKKAEDQDSEQERARKPRKPRAPGTRREQPAGLPSPGERSAAGTRAPRGHKRKLNEEDAASESSGESSNDDEEGSSSEADEMAAALEAELNDLM----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TSG2-1", "uniprot_id": "CTDP1_MOUSE", "id": "Q7TSG2-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase", "aln": "---------------------------------------------------------MEAPPAAGVPTECTPAVAGAEVRCPGPTPLRLLEWKVAAGATVRI-GSVLAVCETAASAQPAGPAPARAASGGCVRAARTERRLRSERAGVVRELCAQPGQVVAPG-ALLVRLEG-CSHPVVMKGLCAECGQDLTQLQSKNGRQQVPLSTATVSMVHSVPELMVSSEQAEKLGREDQQRLHRNRKLVLMVDLDQTLIHT-----------TEQHCPQMSNKGIFHFQLG---------------------RGEPMLHTRLRPHCKDFLEKIAKLYELHVFTFGSRLYAHTIAGFLDPEKKLFSHRILSRDECIDPFSKTGNLRNLFPCGDSMVCIIDDREDVWKFAPNLITVKKYVYFPGTGDVNAPPAARETQARRKVNHSSKGGDALEQALSVRDPEDGRPAPGVEHSNGLGKASRELNGGEAVP---GVFPSKADEKEAWPLTRASPASSSSGHEPTEAPELPVSCEWDGRTTPGVQPTQGDAATQDLDFDLSSDSESSESSSRSEGQR------------------APAPQERTKAAPEHSGPQDTSGGRAAASPLGESGPSIHPHDKGSDLDTQEEGERDSLCGLGNGSVDRKEAETESQNSEQSGVTAGESLDQSVGEEEEEDTDDDDHLIHLEEILVRVHTDYYTKYDRYLNKELEEAPDIRKIVPELKSKVLADVAVIFSGLHPTNFPVEKTREHYHATALGAKVLTQLVLSPDAPDRATHLIAARAGTEKVRQAQEC-KHLHVVSPDWLWSCLERWDKVEEQLFPLIDDDTRTHRDNSPAVFPDRHSVLPTALFHPTPIHSKAHPGPEVRIYDSNTGKLIRMGPQGSAPAPSSAPLNHGEPSSFRAVQPHQQQMFGEELPESQDGEQPGPARRKRQPSMSEAMPLYTLCKEDLESMDKEVDDILGEGSDDSDIEKKKPEDQDNEQERAPKPRKPRAPGIRREQPVGLPSSGERSTPGMRGPRGHKRKLNEEDAASESSGESSNDDEEGSSSEADEMAAALEAELNDLM----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5B0-1", "uniprot_id": "CTDP1_HUMAN", "id": "Q9Y5B0-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase", "aln": "---------------------------------------------------------MEVPAAGRVPAEGAPTAAVAEVRCPGPAPLRLLEWRVAAGAAVRI-GSVLAVFEAAASAQSSGASQSRVASGGCVRPARPERRLRSERAGVVRELCAQPGQVVAPG-AVLVRLEG-CSHPVVMKGLCAECGQDLTQLQSKNGKQQVPLSTATVSMVHSVPELMVSSEQAEQLGREDQQRLHRNRKLVLMVDLDQTLIHT-----------TEQHCQQMSNKGIFHFQLG---------------------RGEPMLHTRLRPHCKDFLEKIAKLYELHVFTFGSRLYAHTIAGFLDPEKKLFSHRILSRDECIDPFSKTGNLRNLFPCGDSMVCIIDDREDVWKFAPNLITVKKYVYFQGTGDMNAPPGSRESQTRKKVNHS-RGTEVSEPSPPVRDPEGVTQAPGVEPSNGLEKPARELNGSEAATPRDSPRPGKPDERDIWPPAQAPTSS----QELAGAPEPQGSCAQGGRVAPGQRPAQGA-TGTDLDFDLSSDSESSSES---EGTKSSSSASDGESEGKRGRQKPKAAPEGAGALAQGSSLE--PGRPAAPSLPGEAEPGAHAPDKEPELGGQEEGERDGLCGLGNGCADRKEAETESQNSELSGVTAGESLDQSMEEEEEEDTDEDDHLIYLEEILVRVHTDYYAKYDRYLNKEIEEAPDIRKIVPELKSKVLADVAIIFSGLHPTNFPIEKTREHYHATALGAKILTRLVLSPDAPDRATHLIAARAGTEKVLQAQEC-GHLHVVNPDWLWSCLERWDKVEEQLFPLRDDHTKAQRENSPAAFPDREGVPPTALFHPMPVLPKAQPGPEVRIYDSNTGKLIRTGARG-PPAPSSSLPIRQEPSSFRAVPPPQPQMFGEELPDAQDGEQPGPSRRKRQPSMSETMPLYTLCKEDLESMDKEVDDILGEGSDDSDSEKRRPEEQEEEPQ-------PRKPGTRRERTLGAPASSERSAAGGRGPRGHKRKLNEEDAASESSRESSNEDE-GSSSEADEMAKALEAELNDLM----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W147-1", "uniprot_id": "Q9W147_DROME", "id": "Q9W147-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase", "aln": "--------------------------MQNIPDEEGATPSRAPGGVAASGAAEGDDGGGGSGAKNSASGNSNNNTSGGGIIVLRAALGENEARAVINKWRVRE-GQFVSAAQILFLYQPVGVDAKDAKDAGKPGGDCAIQRYKSQRAGVVKKRLRKEGELLTKG-DAILELSE-CIHTTVIKDMCADCGADLRQNENGQ------TSEASVPMVHTMPDLKVTQKLAQKLGHDDTRRLLADRKLVLLVDLDQTVIHT-----------TNDTVPDN-IKGIYHFQLYG--------------------PHSPWYHTRLRPGTAEFLERMSQLYELHICTFGARNYAHMIAQLLDPEGKFFSHRILSRDECFNATSKTDNLKALFPNGDSMVCIIDDREDVWNMASNLIQVKPYHFFQHTGDINAPPG------LSKHELDGEGVDFKEITEKHGDKDKTESSSEVKPED-------TDKGDNTVT-----STSKDDDVNEESVDVFEIEG--------DAKDPEVSNASSATEAPKEPRDKLNGKTNAEDIVVIDDSSSGSPD------------------------AEKAASDGEDVVVIDDNSKESTKAEVPPTP----------------------AEKNEVVASSTTSPDEKRPSADADVATTSKTPSLRAPLEGQKQIEIEDPD--DYLLYLEVILRNIHKRFYSIYD-----ETTEIPDLKVIVPKIRSEVLRGKNLVFSGLVPTQMKLEQSRAYFIAKSLGAEVK------PNIDKEITHLVAVNAGTYKVNAAKKE-PAIKVVNANWLWTCAERWEHVEEKLFPLDRKVRNKGRQPPAHCHSPEHVVNYSERSEISPSSSKQQEEQSGNFRETLNPLLVFTNADIESMNKDYETFFESDSSSDEGPVNFENPPMDKKLLK----------RKREDDNSNRAHDFFTRSDDIMIGAPNLVEVDISSNEEADDNNEKEDDDDE-------------MPSAKFRRGEDLPS--------------------DLELGSESNSEKEPEDE--DDGEWNMMGAALEREFLGLEDFDM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03254-1", "uniprot_id": "FCP1_YEAST", "id": "Q03254-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase", "aln": "----------------------------------------------------------MTTQIRSPQGLPYPIQIDKLIPSVGSYLHEGDRLLVYKFWYLVERASDTGDDDNEHDVSPGGSAGSNGVSPPTKQLRESIEFFESPYEGDLISWNVDVGDEVATANQVICEIKRPCNHDIVYGGLCTQCGKEVSAD----------AFDGVPLDVVGDVDLQISETEAIRTGKALKEHLRRDKKLILVVDLDQTIIHCGVDPTIAEWKNDPNNPNFETLRDVKSFTLDEELVLPLMYMNDDGSMLRPPPVRKCWYYVKVRPGLKEFFAKVAPLFEMHIYTMATRAYALQIAKIVDPTGELFGDRILSRDENGSLTTKS--LAKLFPTDQSMVVVIDDRGDVWNWCPNLIKVVPYNFFVGVGDIN------------SNFLPKQSTGMLQLGRKTRQKS------------------------------------------------------------QESQELLTDIMDNEKKLQEKIDKEVKRQEEKLNHQLATAEEPPANE-------------------------------------------------------------------------------------SKEELTKKLEYSASLEVQQQNRPLAKLQKHLHDQKLLVDDD--DELYYLMGTLSNIHKTYYDMLS----QQNEPEPNLMEIIPSLKQKVFQNCYFVFSGLIPLGTDIQRSDIVIWTSTFGATST------PDIDYLTTHLITKNPSTYKARLAKKFNPQIKIVHPDWIFECLVNWKKVDEKPYTLIVDSPISDEE--------------------LQNFQTQLQKRQEYLEETQEQQHMLTSQENLNLFAAGTSWLNNDD-------------------------------------------------------DEDIPDTASDDDEDDDHDDESDDENN-------------SEGIDRKRSIEDNHDDT-----------------SQKKTKAEPSQDGPVQHKGEGDDNEDSDSQLEEELMDMLDD--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . * : .. . : .. * . . . .* * : . . *: :: . : .:. * * * .:*::** :: . * :* ::. * : *: .:* ::**:*:******:** : :.: * * . :.::** :*: ::: *:*:*: *:.:* ** ** ::** ::*..******* . :*: * *** .:*** :**** ***: ..*** * * :* .**:* . .. : : . : : . . : : : ... . .. .* : : . . . . : * * * * :* * .:*. :* . : *:: *:*.::.:*: . .:**** * :::: :.::** *: ***:: ...* *. *:: :::* .:*:: * .*.:*:*: :.* . .: . . : :: : . . : : : ....: .: :.. :::: . .: . . . . :. :. ...: : ** *: .: ", "identical_positions": 112, "similar_positions": 207, "identity": "10.39%" }, { "cls_id": "homologset.agr.SGD:S000004891", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FLB2-1", "uniprot_id": "F7FLB2_RAT", "id": "F7FLB2-1", "name": "", "aln": "MEDNGRLLERVTGPPPLGCGSDRMAAATPTQTP---APEASGLGMDARLDQETAQWLRWDRNPLTSESVKQLLAEGNKEELEKCFGARMEFGTAGLRAPMGAGISRMNDLTIIQTTQGFCRYLEKQFSDLKQ---RGVVISFDGRAHPASGGSSRRFARLAATAFISQGVPVHLFS---DITPTPFVPYTVSHLKLCAGIMITASHNPKQDNGYKVYWDNGAQIISPHDRGISQAIEENLEPWPQAWDESLIDSSSLLHN----PSTSISNDYFEDL-KKYC--FHRTVNRESQVKFVHTSVHGVGH----EFVQSAFKAFDLNPPEAVPQQKDPDPEFPTVKYPNPEEGKGVLTLSFELADKIKAKIVLANDPDADRLAVAEKQD-SGEWRVFSGNELGALLGWWLFTSWKEKNQGQSNLKDTYMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRAKQLIDQGKTVLFAFEEAIGYMCCPFVLDKDGVSAAVISAELVSFL-ATKNLSLSLQLKAIYLEYGYHITTASYFICHDQGTIQKLFENLRNYDG--KNKYPKTCG--KFEISAVRDLTTGYDSNQPDKKAVLPTSKSSQMITFTFV--NG-----GVATMRTSGTEPKIKYYAELCAPPGNSDPEQLKRELDELVGAIEEHFFQPQKYNLQPKAE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TSV4-1", "uniprot_id": "PGM2_MOUSE", "id": "Q7TSV4-1", "name": "Phosphopentomutase", "aln": "-----------------------MAAATPTETP---APEGSGLGMDARLDQETAQWLRWDQNPLTSESVKQLIAGGNKEELRKCFGARMEFGTAGLRAPMGAGISRMNDLTIIQTTQGFCRYLEKQFSDLKQ---RGVVISFDARAHPASGGSSRRFARLAATAFITQGVPVYLFS---DITPTPFVPYTVSHLKLCAGIMITASHNPKQDNGYKVYWDNGAQIISPHDRGISQAIEENLEPWPQAWEESLVDSSPLLHN----PSASIGNDYFEDL-KKYC--FHRTVNKESKVKFVHTSVHGVGH----EFVQLAFKAFDLAPPEAVPQQKDPDPEFPTVKYPNPEEGKGVLTLSFALADKIKAKIVLANDPDADRLAVAEKQD-SGEWRVFSGNELGALLGWWLFTSWKEKNQDQSNLKDTYMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRAQQLGDQGKTVLFAFEEAIGYMCCPFVLDKDGVSAAVICAELASFL-ATKNLSLSQQLNAIYVEYGYHITTASYFICHDQGTIQNLFGNLRNYDG--KNNYPKMCG--KFEISAIRDLTTGYDDSQPDKKAVLPTSKSSQMITFTFA--NG-----GVATMRTSGTEPKIKYYAELCAPPGNSDPEHLKKELDELVGAIEEHFFQPQKYNLQPKAE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96G03-1", "uniprot_id": "PGM2_HUMAN", "id": "Q96G03-1", "name": "Phosphopentomutase", "aln": "-------------------------------MA---APEGSGLGEDARLDQETAQWLRWDKNSLTLEAVKRLIAEGNKEELRKCFGARMEFGTAGLRAAMGPGISRMNDLTIIQTTQGFCRYLEKQFSDLKQ---KGIVISFDARAHPSSGGSSRRFARLAATTFISQGIPVYLFS---DITPTPFVPFTVSHLKLCAGIMITASHNPKQDNGYKVYWDNGAQIISPHDKGISQAIEENLEPWPQAWDDSLIDSSPLLHN----PSASINNDYFEDL-KKYC--FHRSVNRETKVKFVHTSVHGVGH----SFVQSAFKAFDLVPPEAVPEQKDPDPEFPTVKYPNPEEGKGVLTLSFALADKTKARIVLANDPDADRLAVAEKQD-SGEWRVFSGNELGALLGWWLFTSWKEKNQDRSALKDTYMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRAKQLIDQGKTVLFAFEEAIGYMCCPFVLDKDGVSAAVISAELASFL-ATKNLSLSQQLKAIYVEYGYHITKASYFICHDQETIKKLFENLRNYDG--KNNYPKACG--KFEISAIRDLTTGYDDSQPDKKAVLPTSKSSQMITFTFA--NG-----GVATMRTSGTEPKIKYYAELCAPPGNSDPEQLKKELNELVSAIEEHFFQPQKYNLQPKAD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CAA7-1", "uniprot_id": "PGM2L_MOUSE", "id": "Q8CAA7-1", "name": "Glucose 1,6-bisphosphate synthase", "aln": "---------------------MAENADDDLNSN---LLHAPYLTGDPQLDTAIGQWLRWDKNPKTKEQIENLLRNGMNKELRDRLCCRMTFGTAGLRSAMGAGFCYINDLTVIQSTQGMYKYLERCFSDFKQ---RGFVVGYDTRGQVTSSCSSQRLAKLTAAVLLAKDIPVYLFS---RYVPTPFVPYAVQELKAVAGVMITASHNRKEDNGYKVYWETGAQITSPHDKEILKCIEECVEPWNDSWNDNLVDTSPLKKD----PLQDICKKYMEDL-KKIC--FYRDLNSKTTLKFVHTSFHGVGH----DYVQLAFQVFGFKPPIPVPEQKDPDPDFSTVKCPNPEEGESVLELSLRLAEKENARIVLATDPDADRLAVAELQE-NGRWKVFTGNELAALFGWWMFDCWKKNKP-NADVKNVYMLATTVSSKILKAIALKEGFHFEETLPGFKWIGSRIKDLLGNGKEVLFAFEESIGFLCGTSVLDKDGVSAAAVVAEMASFL-DTRKVTLMEQLTKVYEIYGYHMSKTSYFLCYDPPTIKTIFERIRNFES--PKEYPKFCG--AFAILHVRDITTGYDSSQPNKKSVLPVSKNSQMITFTFQ--NG-----CVATLRTSGTEPKIKYYAEMCASPGQSDTTFLEEELKKLIDALIENFLEPSKNALVWRSV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z955-1", "uniprot_id": "D3Z955_RAT", "id": "D3Z955-1", "name": "", "aln": "---------------------MAENANDDLNSN---LLHAPYLTGDPQLDTAIGQWLRWDKNPKTKEQIENLLRNGMNKELRDRLCCRMTFGTAGLRSAMGAGFCYINDLTVIQSTQGMYKYLERCFSDFKQ---RGFVVGYDTRGQVTSSCSSQRLAKLTAAVLLAKDVPVYLFS---RYVPTPFVPYAVQELKAVAGVMITASHNRKEDNGYKVYWETGAQITSPHDKEILKCIEECVEPWDDSWNDNLVDTSPLKKD----PLQDICRRYMEDL-KKIC--FYRDLNSKTTLKFVHTSFHGVGH----DYVQLAFQVFGFKPPIPVPEQKDPDPDFSTVKCPNPEEGESVLELSLRLAEKENARIVLATDPDADRLAVAELQE-NGHWKVFTGNELAALFGWWMFDCWKKSKP-NADVKNVYMLATTVSSKILKAIALKEGFHFEETLPGFKWIGSRIKDLLGHGKEVLFAFEESIGFLCGTSVLDKDGVSAAVVVAEMAAFL-DARKVTLMEQLMKVYETYGYHMSKTSYFLCYDPPTIKTIFERIRNFES--PKEYPKFCG--AFAILHVRDITTGYDSSQPNKKSVLPVSKNSQMITFTFQ--NG-----CVATLRTSGTEPKIKYYAEMCASPGQSDTALLEEELKKLIDALIENFLEPSKNGLIWRSV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PCE3-1", "uniprot_id": "PGM2L_HUMAN", "id": "Q6PCE3-1", "name": "Glucose 1,6-bisphosphate synthase", "aln": "---------------------MAENTEGDLNSN---LLHAPYHTGDPQLDTAIGQWLRWDKNPKTKEQIENLLRNGMNKELRDRLCCRMTFGTAGLRSAMGAGFCYINDLTVIQSTQGMYKYLERCFSDFKQ---RGFVVGYDTRGQVTSSCSSQRLAKLTAAVLLAKDVPVYLFS---RYVPTPFVPYAVQKLKAVAGVMITASHNRKEDNGYKVYWETGAQITSPHDKEILKCIEECVEPWNGSWNDNLVDTSPLKRD----PLQDICRRYMEDL-KKIC--FYRELNSKTTLKFVHTSFHGVGH----DYVQLAFKVFGFKPPIPVPEQKDPDPDFSTVKCPNPEEGESVLELSLRLAEKENARVVLATDPDADRLAAAELQE-NGCWKVFTGNELAALFGWWMFDCWKKNKSRNADVKNVYMLATTVSSKILKAIALKEGFHFEETLPGFKWIGSRIIDLLENGKEVLFAFEESIGFLCGTSVLDKDGVSAAVVVAEMASYL-ETMNITLKQQLVKVYEKYGYHISKTSYFLCYEPPTIKSIFERLRNFDS--PKEYPKFCG--TFAILHVRDVTTGYDSSQPNKKSVLPVSKNSQMITFTFQ--NG-----CVATLRTSGTEPKIKYYAEMCASPDQSDTALLEEELKKLIDALIENFLQPSKNGLIWRSV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z7P1-1", "uniprot_id": "A1Z7P1_DROME", "id": "A1Z7P1-1", "name": "", "aln": "---------------------MCQSGGQMLCE-----IKNMALSGDPELDGEIRKWIRWDKCASTACQIMDAVRAKDWDTLRKRLCTRISFGTAGLRACMRAGFDSMNELVVIQTAQGLCEYIKEQYPDPADWSGRGIVFGYDGRYN------SHRFAELSAIVFLNNDFKVWLFK---RYVATPMVPFAILRLQCLAGVMVTASHNPKEDNGYKVYWTNGAQIIPPHDEGIQESILNNLEPKGSSWDDSAMCSNTMLED----PYDIVVPPYFDIL-KKQLPCTSLEANGRCSLSFTYTAMHGVGY----AFVKQAFARINLKPFISVCEQQEPDPEFPTTPMPNPEEGKTSLDLSIKTAKANSSQIILANDPDADRLAVAEVRE-DGSYKLFSGNEVGALLGWWSLELHKMREP-DCDVSNCVMIASTVSSKILRAMAEREGFQFFETLTGFKWMGNKAIELQQAGKTVLFAFEEAIGFMVGTTVLDKDGVSAAGHLATMACYLRCKLCMTLQEKLRDIYETYGFHTTVSSYVICRCPPVIEQIFERLRTWDEGKADTYPTSILNGEYEIENVRDLTTGFDSSTGDKKATLPTSSSSQMITFTFK--NG-----LVVTLRTSGTEPKMKYYAEMCGKPDEKNWAKLTNTMNTMVEAIVEEFYEPSKNGLQRRKE--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z9V3-1", "uniprot_id": "A1Z9V3_DROME", "id": "A1Z9V3-1", "name": "", "aln": "---------------------MSISVKRKTVISPQELLKTLELSGEEDLDLQIKNWVMWDRNEATLQQVTEAVRDQDWKALRVRLCHRITYLTTGLRGVMRAGFDSLNDVVIIEVAQGICAYLVDAYPSIQKRQTQGVVVGYDGRYN------SKRFAQLIATVFLNNDFKVFLFT---RMIPTPFIPFTVVTLQCLAGIVVTASHNVKEDNGIKVYWSNGAQAMAPHDQRIHDYMMNNLEPKPSSWETSLVLDHPLVED----PYRQIYPLFYEAL-KTLIPPIYLETNECSQLRFIYTALHGVGY----PFMREAFYQARLKPVIPVVEQKEADPEFPTLVKPNPEEGKEALKLAIKKADAEHCTLVLANDPDVDRLAVAELDP-RGRWKLFNGNELGALLGWWALENYKTRTP-KPAVTNCIMIATLVSSRILAAMARVEGFIFVEGMPSFPWMAHRALELEKSGRTVLFAFEECFGYMFGMSLPDKDGIGAAMQLASMACYLRSTRNVTLIEKLREIYDTYGYHSSISSVYMADSPETITSVFDHLRNFTD--EEGYPKFILDEEFEVVHIRDLTIGLDTSFSDGKARMPVTPDAQLITFTFT--NG-----YVVTLRSAPNDIKIKLNAEICGLPEEKQWEELHDKLNRMTNAVVEEFLQPEENGLTDASTIQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03262-1", "uniprot_id": "PGM3_YEAST", "id": "Q03262-1", "name": "Phosphoribomutase", "aln": "------------------------------------MLQGILETVPSDLKDPISLWFKQDRNPKTIEEVTALCKKSDWNELHKRFDSRIQFGTAGLRSQMQAGFSRMNTLVVIQASQGLATYVRQQFPDNLV-----AVVGHDHRFH------SKEFARATAAAFLLKGFKVHYLNPDHEFVHTPLVPFAVDKLKASVGVMITASHNPKMDNGYKVYYSNGCQIIPPHDHAISDSIDANLEPWANVWDFDDVLNKALKQGKLMYSREEMLKLYLEEVSKNLVEINPLKLEVKAKPWFVYTPMHGVGFDIFSTIVKKTLCLVEGKDYLCVPEQQNPDPSFPTVGFPNPEE-KGALDIGINLAEKHDIDLLVANDPDADRFSVAVKDMQSGEWRQLTGNEIGFLFAFYEYQKYKSMDKEFQHVHPLAMLNSTVSSQMIKKMAEIEGFHYEDTLTGFKWIGNRAILLEKKGYYVPFGFEEAIGYMFPAMEHDKDGISASIVFLQAYCKWKIDHNLDPLNVLENGFKKYGVFKEYNGYYVVPNPTVTKDIFDYIRNVYTPEGASYPSSIG-EEIEVLYYRDLTTGYQSDTINHKPTLPVDPTSQMITVSARPSNGSENEHIRFTIRGSGTEPKLKVYIEACANEEQRASFLAKLTWNVLR----REWFRPDEMNIVTKF---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *. *. *: * : . *. : *: : *:***. * .*: :* :.:*: :**: *: :.. *...* * : *:.:*. * .:: :.. * :. **::*::: *: .*:::***** * *** ***: .*.* .***. * . : :** *: . : .: .. . : : : : *. : * :*..****. :: :: * :*::.**.*.* ***** : * :.: *. :::*.***.**::.* * :: :.***:. *:.:: * : *: : ***::: :* *** : : :..* *:. : * * * *.***.:*:: ****:.*: . : * : ** . . : . :* :*. **. : **:* * : . : *. :*. :*:**.: ** *:* : .: *:* * *. : . : ..: .*.: : ", "identical_positions": 131, "similar_positions": 172, "identity": "19.32%" }, { "cls_id": "homologset.agr.SGD:S000004892", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VPE0-1", "uniprot_id": "Q9VPE0_DROME", "id": "Q9VPE0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "MAQLKFLRPLVKVLVNRSGIGKASVWHAVIVTFMHYFSWGLLTVPFIEKLSGSFGNRVLLVDGLVYGVRGILGFVTTPVMGAISDFHGRKVVMLLAVATTYAPIPFMMLKSWWFFAILTVSSICGSTYSSSLAYVADTTTVENRSKGYGIVAASFGAGIAFSPSLGNYLMKS--YGSASVILIAAITGLINIMFIIFAVPESLVLKEKNNMLDEESDN-----KMEDINPKERKEILNREEKLNNHVSANKSNHGTSQNLVTNKELGQQFNKEENLQNDLTEKEKIDNGSLNSSDLWEVLRKSRKDK----NLLVIYLITFLSIWPFAGVDSTAPVYLKTNMGFEYEEVSMMLGLL--SVLAITSNLLLGYIINIVGAKWSIRLGLLLLLLQLFFFGFGTHHWMYWLSSILAALATIIPAANNAVASIYASPDNRGAVLGIISGIECLSEGVGPAFFGVLFFIFQDDSKN--KVNSPIS------MPFVISAIGVFVAIVLTGFIKKETVEKAPLIYKIIDDASEDEVEPLAKTTFKYEKNNGYVKLEIDDNYDSDCKEHSFK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPD9-1", "uniprot_id": "Q9VPD9_DROME", "id": "Q9VPD9-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "MAQLKFLRPLVKVLVNRSGIGKASVWHAVIVTFMHYFSWGLLTVPFIEKLSGSFGNRVLLVDGLVYGVRGILGFVTTPVMGAISDFHGRKVVMLLAVATTYAPIPFMMLKSWWFFAILTVSSICGSTYSSSLAYVADTTTVENRSKGYGFVAASFGAGIAFSPSLGNYLMKS--YGSASVILIATITGMINILFIIFAVPESLVLKEKKVILNENNDNKVEDTKVDDISPKEKKENLNGEGKVN--VEVNKP---TSQNIVTNKELDQQFSKEENLQNDLTEKEKIDNGSLNSSDLWEVLRKSRKDK----NLLVIYLITFLSIWPFAGVDSTAPVYLKTNMGFEYEEVSMMLGLL--SVLAITSNILLGYIMNIVGAKWSIRLGLLLLFLQMLFFGFGTHHWMYWLSSILAALATIIPAANNAVASIYASPDNRGAVLGIISGIECLSEGVGPAFFGLLFFIFQDDSETDLKVNSPIS------MPFVISAISVFVAIVLSSFIKKDTLGNE-------ETRVANENIP---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPD8-1", "uniprot_id": "Q9VPD8_DROME", "id": "Q9VPD8-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "MSKFG-LKKLLVSLASTSGIGKPSVGHILVVVFLEYFAWGLLTMPMIATLKETFPDHTFLMNGLVMGVKGILSFLSSPLIGALSDIYGRKVLLLITVIFTSLPIPMMTMDNWWFFVISSISGVLGVSFSVAFAYVADVTTKEERSRSYELVSATFAASLVIAPAMGNLIMDR--YGINTVVLVATLVSTTNVMFVLLAVPETLQQNVRSTGL-----------------------------------------------------------------------------SWKQADPFLSLRRVGSDP----NVLLLCVVMFTFLLPEAGEYSSVPAYLKLTMGFDFTELSTLVAFM--AILGISINVTLGSIVKTLGAKNAIILGLLLELLQLILFAIGYEKWQMWLAGNVAALSSITFPAVSAYVSLYTDVETQGAVQGMITGMSGLCSGLGPALFGIVFYLSDMDLDKNRILIGSVSGDRTVTNPFMIGAISVFIGILLASYIPDEKVSRG----RREEFSALKYIIEMEEATTI--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03263-1", "uniprot_id": "YM8M_YEAST", "id": "Q03263-1", "name": "Uncharacterized transporter YMR279C", "aln": "--MFSIFKKKTSVQGTDSEIDEKITVKAKDKVVVSTEDEEVTTIVSSTKSTQVTNDSPWQDPTYFSSFGKELMFIATCMLAQLLNQAGQTHALCIMNVLSKS-FNSEANNQAWLMASFPLAAGSFILISGRLGDIYGLKKMLIVGYVIVIVWSIISGLSKYSNSDAFFITSRAFQGVGIAFILPNIMGLVGHVYKVGSFRKNIVISFIGACAPTGGMFG---------GLFGGLIVTEDPNQWPWVFYAFGIATFLSLLMAWYSIPNNVPTNIHGLSMDWTGSALAIIGLILFNFVWNQAPIVGWDKPYIIVLLIISVIFLVAFFVYESKYAEVPLLPRAMTKNRHMIMILLAVFLGWGSFGIWTFYYVSFQLNLRHYSPVWTGGTYFVFVIFGSMAAFFVAFSIKRLGPALLLCFSLMAFDAGSIMFSVLPVEQSYWKLNFAMQAILCFGMDLSFPASSIILSDGLPMQYQGMAGSLVNTVINYSASLCLGMGGTVEHQINKSGNDLLKGYRAAVYLGVGLASLGVVISVTYMLENLWNRHRKSEDRSLEA-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: . * *.: . : ..: : *: . . : . .. * *::: ::. : : *:. : : : : .. *::. .::. * :. : . .. . :* : :.. : : . : . * ..::. : . . :: : :. :.: . : * :*:: :: : : . : .* : . : : :: . :.* :. :: . * : :: : :. : . *. . . : . :. :: *. *:. :: . : : : : ..: . : .:. : : . ", "identical_positions": 18, "similar_positions": 139, "identity": "3.2%" }, { "cls_id": "homologset.agr.SGD:S000004894", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35790-1", "uniprot_id": "PIGL_RAT", "id": "O35790-1", "name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase", "aln": "------------------------------------------------MEVVGLLCVAVAVLT-----WGFLRVWNSAERMRSP--------------EQAGLPGAGS--------------------------------RALVVIAHPDDEAMFFAPTILGLARLK---QQVSLLCFSSGNYYNQGEIRKKELLQSCAVLGIPPSRVMIIDKREFPDDPEVQWDTEHVASTILQHIHANATDL---VVTFDAEGVSGHSNHIALYKAVRALHSGGKLPEG--------CSVLTLQSVN--VLRKY----VFLLDLPWTLLSPQGVLFVLTSKEVAQAK-----------------KAMSCHRSQLLWFRHLYTVFSRYMSVNSLQLL--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SX19-1", "uniprot_id": "PIGL_MOUSE", "id": "Q5SX19-1", "name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase", "aln": "------------------------------------------------MELVGFLCVAVAVLT-----WGFLRVWNSAERMRSP--------------EQAGLPGAGS--------------------------------RALVVIAHPDDEAMFFAPTMLGLARLE---QQVSLLCFSSGNYYNQGEIRKKELLQSCAVLGIPPSRVMIIDKRDFPDDPEVQWDTELVASTLLQHIHANGTDL---VVTFDAEGVSGHSNHIALYKAVRALHSGGKLPKG--------CSVLTLQSVN--ALRKY----AFLLDLPWTLLSPQDVLFVLTSKEVAQAK-----------------KAMSCHRSQLLWFRYLYVLFSRYMRINSLRFL--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2B2-1", "uniprot_id": "PIGL_HUMAN", "id": "Q9Y2B2-1", "name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase", "aln": "------------------------------------------------MEAMWLLCVALAVLA-----WGFLWVWDSSERMKSR--------------EQGGRLGAES--------------------------------RTLLVIAHPDDEAMFFAPTVLGLARLR---HWVYLLCFSAGNYYNQGETRKKELLQSCDVLGIPLSSVMIIDNRDFPDDPGMQWDTEHVARVLLQHIEVNGINL---VVTFDAGGVSGHSNHIALYAAVRALHSEGKLPKG--------CSVLTLQSVN--VLRKY----ISLLDLPLSLLHTQDVLFVLNSKEVAQAK-----------------KAMSCHRSQLLWFRRLYIIFSRYMRINSLSFL--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P3K2-1", "uniprot_id": "A0A8M1P3K2_DANRE", "id": "A0A8M1P3K2-1", "name": "N-acetylglucosaminylphosphatidylinositol deacetylase", "aln": "---------------------------------------------MFVFFTISFVLVAYAVFIKFVY-YRHSQLWPHALNKISTPLYTVGNSRFCPAQERSGALFPNSEDENPRE------------------------TRALIVTAHPDDECMFFAPTVLRLVESR---AAVCLLCLSTGNYNNQGLQRKKELLDSCAVLGIPANHVSIIDDKELPDDPAVQWSTALISSLILKHIQNYAISL---VLTFDGRGVSGHANHIAIYKTLSHLASAGRIHEG--------CQIFSLHSIS--IIRKY----LSILELPVSWLLPSDFCCIIGREDYKRAK-----------------KAMLCHRSQLLWFRRLYILFSRYMFVNTFQAITAETKNVKIY----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K6Q5-1", "uniprot_id": "A0A0B4K6Q5_DROME", "id": "A0A0B4K6Q5-1", "name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase", "aln": "MRFNWLSEYVASISSSIASTSPWRQLQQQVQQLVPNPQAIYCRIRSSSAEALEHVLIACAVYLLVCLGLYKLTFWLSGAGSGSGLDAHHNGNDTSNAGSGEGAELNPSSDGNRSPGGLKQALQSGIRLRSVRLPKTACMERVLLITAHPDDECMFFGPLIYSLTQRQG--CQVYILCLSNGNFEHKAKVRRQELWRSCSKLGIPESNIVLMNATNLPDDPYVDWRPDAVASLILHTIESLDIQA---IFTFDRDGVSSHPNHCAVYYAAASLCLANLLPKD--------CKFYTLDSIN--VVRKY----LSILDLLCTCFMST-HRCILNWKEAAIVR-----------------SAMMEHQSQMRWFRWLYIYFSRYMFINSMRQINLSDVELEMQIHDN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23797-1", "uniprot_id": "GPI12_YEAST", "id": "P23797-1", "name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase", "aln": "-------------------------------------------MKMLRRTKVNFSKLLYKITKLAIVLTILYIYFTPKIVSRNN--------------ASLQHIFPHKYG----------------------------DYEINLVIAHPDDEVMFFSPIISQLNSYFPRTVPFNIICLSKGNAEGLGETRVRELNESAALL-LHNERAVSVQVMDFQDGMDEIWDIDSITSSLSQKIDIKNHNLNQIIVTFDSYGVSNHINHKSCYAAVKKLVDDYAQPKTKRNEQPPHVTALYLRSYKNNIVLKYNSFIWEILKILYDLISPFRRIIQALPPNTAAEKDKLSLMNTHAQYVLAFATMLNAHESQVVWFRYGWWIFSRFVFVNEFDVYTY------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . . . :: ****** ***.* : * . ::*:* ** . * :** *. * : . :: :: *. * :: : : *. . :.*** ***.* ** : * : * : * * . : ** :*.: : . : : . : *.**: *** : ***:: :* : ", "identical_positions": 49, "similar_positions": 55, "identity": "12.19%" }, { "cls_id": "homologset.agr.SGD:S000004897", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PT85-1", "uniprot_id": "E9PT85_RAT", "id": "E9PT85-1", "name": "DNA repair protein Ku70", "aln": "MSEWESYYKTEGEE--EEEEEQSPDTNGEYKYSGRDSLIFLVDASRAMFESQGEDELT-PFDMSIQCIQSVYTSKIISSDRDLLAVVFYGTEKDKNSVN---------FKSIYVLQDLDNPGAKRVLELDRFKGQQGKKHFRDT----IGHGSDYSLSEVLWVCANLFSDVQ---FKMSHKRIMLFTNEDDP-HGNDSAKASRARTKASDLRDTGIFLDLMHLKKRGGFDVSLFYRDIISI---AEDE-DLGVHFE---ESSKLEDLLR-KVRAKETKKRVLSRLKFKLGKDVALMVGVYNLVQKANKPFPVRLYRE-TNEPVKTK---TRTFNVNTGSLLLPSDTKRSLT-------FGTRQIVLEKEE---TEELKRFDEPGLILMGFKP-MVMLKNHHYLRPSLFLYPEESLVNGSSTLFSALLTKCVEKEVIAVCRYTARKNVSPYFVALVPQEE----ELDDQNIQVTPAGFQLVFLPYADDKRKVPFTEK----VMANPEQIDKMKAIVQ------KLRFTYRSDSFENPVLQQHFRNLEALALDMMESEQVVDLTLPKVEAIKKRLGSLADEFKELVYPPGYNPEGK-IAKRKADNEG--SASKKPKVELSEEELKDLFAKG-TLGKLTVPALRDICK-AYGLKS-GPKKQELLEALSRHLEKN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23475-1", "uniprot_id": "XRCC6_MOUSE", "id": "P23475-1", "name": "DNA repair protein Ku70", "aln": "MSEWESYYKTEGEE--EEEEEESPDTGGEYKYSGRDSLIFLVDASRAMFESQGEDELT-PFDMSIQCIQSVYTSKIISSDRDLLAVVFYGTEKDKNSVN---------FKNIYVLQDLDNPGAKRVLELDQFKGQQGKKHFRDT----VGHGSDYSLSEVLWVCANLFSDVQ---LKMSHKRIMLFTNEDDP-HGRDSAKASRARTKASDLRDTGIFLDLMHLKKPGGFDVSVFYRDIITT---AEDE-DLGVHFE---ESSKLEDLLR-KVRAKETKKRVLSRLKFKLGEDVVLMVGIYNLVQKANKPFPVRLYRE-TNEPVKTK---TRTFNVNTGSLLLPSDTKRSLT-------YGTRQIVLEKEE---TEELKRFDEPGLILMGFKP-TVMLKKQHYLRPSLFVYPEESLVSGSSTLFSALLTKCVEKKVIAVCRYTPRKNVSPYFVALVPQEE----ELDDQNIQVTPGGFQLVFLPYADDKRKVPFTEK----VTANQEQIDKMKAIVQ------KLRFTYRSDSFENPVLQQHFRNLEALALDMMESEQVVDLTLPKVEAIKKRLGSLADEFKELVYPPGYNPEGK-VAKRKQDDEG--STSKKPKVELSEEELKAHFRKG-TLGKLTVPTLKDICK-AHGLKS-GPKKQELLDALIRHLEKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12956-1", "uniprot_id": "XRCC6_HUMAN", "id": "P12956-1", "name": "DNA repair protein Ku70", "aln": "MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELT-PFDMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVN---------FKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDM----MGHGSDYSLSEVLWVCANLFSDVQ---FKMSHKRIMLFTNEDNP-HGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISI---AEDE-DLRVHFE---ESSKLEDLLR-KVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRE-TNEPVKTK---TRTFNTSTGGLLLPSDTKRSQI-------YGSRQIILEKEE---TEELKRFDDPGLMLMGFKP-LVLLKKHHYLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEE----ELDDQKIQVTPPGFQLVFLPFADDKRKMPFTEK----IMATPEQVGKMKAIVE------KLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGK-VTKRKHDNEG--SGSKRPKVEYSEEELKTHISKG-TLGKFTVPMLKEACR-AYGLKS-GLKKQELLEALTKHFQD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QZ60-1", "uniprot_id": "F1QZ60_DANRE", "id": "F1QZ60-1", "name": "", "aln": "MANWGNYFPNEDDVD-EQDEEES---GGDYKSSGRDSLVFLVDASKEMFIKGENGEPS-NFDMTMQCVRSVYTSKIISSDRDLVALVFYGTEQSKNPRNS--------FKHVYVYHDLESPGAKRVQDIDKLKGDKGGQFAEKT----MGSG-ETSLGEALWCCSNLYSDIK---LRLSHKRLMIFTCRDEP-HGGDSAKDRQARTKAADLKETGVAIDLMHLSKPGGFDVSLFFCDIVSP---PEDESDLGLQIE---PCRKLEDLQK-RVRAKELKKRAQCRLTFSLGEGVDLAVGVYVLARTAMKPSAVKLYRD-NNEPVRTK---SRLFHTQTGGILLPNDTKRAQV-------YGQKQIVMEKDE---VDEIKKFDDPGLVLIGFKP-IDRLKLHHHLRPALFIYPEEEQISGSSCMFTALLLKCCEKNVFALCKYIPRRNTPPRFVALVPQRE----ELDQSQTQATPPGFHVIYLPFADDIRTVDPHVG----PTASDEQVDKMKEIVH------KLRFKYRSDAFENPVLQQHYSNLEALALDMLSPEPIEDLTMPKVKMMDDRLGPLVQEFKDLVYPPDYNPEGKPAAKRKPAESGGGAAEKKAKVEISEEELKIHVAKG-TLGKLTVPVLKDACK-QFNIRTTGTKKQELIDALTMQLSK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q23976-1", "uniprot_id": "KU70_DROME", "id": "Q23976-1", "name": "ATP-dependent DNA helicase 2 subunit 1", "aln": "MSTWN----PENDVDLLSGSEDEEDVSMKRDYHGREAILFVVDAN------LQTAGVE-RLLEALNIIRTAFISGLLVNDKDLIGLIFANTKHSPPPLEASALDNIVMPDNCAVFLPLRQLTKPIVEHYLEFMGGVETQFADVYGL--AEPDGRGRFDLMIRLCIEMLEKCG---KKLNNAKIAYVTDVREP-HPSNSNHFQAALQKASDLEGK--EFEFHVIPMVDDFDYEPFYKEFITL---SRAIELDAFQVP---DAQMLREILSDRKLKQDFLRRCLGHFSFYLGPNLSMSVQYYNYFQRRAYPRKVQILRR-DNSVVRTKRVITVQKQKDDGSQDIEHEYQIKVTGGWYTCNVGERDLRISMDQ---LNRVRNLHKPQMMLLGFKH-RSSLPEVSYIKPANFMYPDDQSIIGSKRLFRALWERCLVRDKIAICLFMCKRKSIPRYVALVPVEAPDNGEDKNYRSLLCGDGFKIVYLPEAKHIRHLDLQDWNNTENTADEQKVEFFQKIIK------KLRVDYQPNLINDPSLDALQANLLALSLDFSTDTKGLDN-LLDTSQQDKRIEKLLPDY--EMFAPEAEPHKKRAAKSTTAGASGPKMAKIDDDQLKEFEFVKSLNKDEALTSCTAAQLHFILQHHFDVTMPKSSKKAKLVAKIEELHK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32807-1", "uniprot_id": "KU70_YEAST", "id": "P32807-1", "name": "ATP-dependent DNA helicase II subunit 1", "aln": "MRSVTNAFGNSGELN------DQVDETGYRKFDIHEGILFCIELSETMFKESSDLEYKSPLLEILESLDELMSQLVITRPGTAIGCYFYYCNREDAKEG---------IYELFPLRDINATFMKKLNDLLEDLSSGRISLYDYFMFQQTGSEKQVRLSVLFTFMLDTFLEEIPGQKQLSNKRVFLFTDIDKPQEAQDIDERARLRRLTIDLFDNKVNFATFFIGYADKPFDNEFYSDILQLGSHTNENTGLDSEFDGPSTKPIDAKYIKSRILRKKEVKRIMFQCPLILDEKTNFIVGVKGYTMYTHEKAGVRYKLVYEHEDIRQEAYSKRKFLNPITGEDVTGKTVKVYP-------YGDLDINLSDSQDQIVMEAYTQKDAFLKIIGFRSSSKSIHYFNNIDKSSFIVPDEAKYEGSIRTLASLLKILRKKDKIAILWGKLKSNSHPSLYTLSPSSV-----------KDYNEGFYLYRVPFLDEIRKFPSLLSYD-DGSEHKLDYDNMKKVTQSIMGYFNLRDGYNPSDFKNPLLQKHYKVLHDYLLQIETTFDENETPNTKKDRMMREDDSLRKLYY--------------------------IRNKILESEKSEDPIIQRLNKY--------VKIWNMFYKKFNDDNISIKEEKKPFDKKPKFNI-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ..: :. . ::.::* :: . : :: : . :: :. * ::. : : . . . . :. : : . ::.: :: .* .* . : . : ** . : : . . *: ::: .. .. . : :. :* : : *. : * :: :. :: : . . : . * :: :. .: . ... : ::**: : : : *: *:: ** : :* :. *: : : * :* * ** : :* .. * . . :: : . :** *... :::* *: * *:: : . . . * : * . : .* : . * : .. .:: .: ", "identical_positions": 38, "similar_positions": 148, "identity": "5.66%" }, { "cls_id": "homologset.agr.SGD:S000004898", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RGT6-1", "uniprot_id": "ANGE2_DANRE", "id": "Q5RGT6-1", "name": "RNA 2',3'-cyclic phosphatase angel2", "aln": "---------------MRKGRHMPRHTNANYAR--------------------------PGVSPNHPMFGRYLSTVGFPPAQNVYNHWRHWYQPGHLWWTQPPQLQHP-------SSSFSTVRHPFN-RPPRPPDP---YQWSSWRQTGVLPHTRGLHLSAGLMESTDRPPPQK-------------------------RRKSAEGEISQRSPQHSPPKGSRSPKGSPEWLRNVSSIEVANRTSAVPELKRHWEDLSHLCKAAPSVNRGKQ-----------------------------------KWPFDFSVMSYNILSQDLLC---DNTYLYRHCNPPVLDWRNRFPNIIKELEQYSADIMCLQEVQEDHYKQQIKPSLESLGYHC------EFKRRTGLKPDGCAVIFKRERFSLVSCHPVEYFRRG----VPLMDRDNVGLIVLLRPIDPH-----------------VSLSNICVANTHLLYNP--RRGDIKLAQLAMLLAEISRVSQL---------PDSSVCPVLLCGDFNSVPWSPLYRFIKDRRLDYDGMPIGKVSGQEETPR---GQRILTVPIWPRSLGISQQCQYENQTR-----------DSELRDLEQTERESFTEAS-----------------------------------------IEHCLRLTSAYSHHLKESGQPEITTCHSRTAITVDYIFYSAALGDVMAQAEYSAP----PERGLQLLGRLALVGEKELQKVNGLPNQHNSSDHLPLLTRFRLHPQADS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1LT13-1", "uniprot_id": "F1LT13_RAT", "id": "F1LT13-1", "name": "", "aln": "---------------METWRCVRRGYGRCVAG--------------------------RGRYSMLPYPLKSLGRDWTTPWEDLQKYCWRRHISSCLRWPG-HYSRAP-------YPYFSSRHFSLNCRPPFLFESGTQFQYYNWRPD-QLSNTSLFHLSRYVMNS-DRDEPSS-------------------------KRRKHQGTIKR----------------SWEYLCSHN-----------KEKTKDLEDRNGDSTCEDCEDK-----------------------------------------FDFSVMSYNILSQELLE---DNSHLYRHCRRPVLHWSFRFPNILKEIKHFDADVLCLQEVQEDHYGTEIRPSLESLGYHC------EYKMKTGRKPDGCAICFKHSKFSLLSVNPVEFCRRD----IPLLDRDNIGLVLLLQPKIPR-----------------AASPSICIANTHLLYNP--RRGDIKLTQLAMLLAEISNVAHQ---------KDGSFCPIVMCGDFNSVPGSPLYSFIKEGKLNYEGLAIGKVSGQEQSSR---GQRILSIPIWPPNLGISQNCVYEAQQVP-----KVEKTDSDVTQAQQEKAEVPVPADKVSSH------------------------------------LQHGFSLSSVYSHYVPDTGVPEVTTCHSRSAITVDYIFYSAEKDDTARGPGAEVA----LVGGLKLLARLSLLTEQDLWTVNGLPNEHNSSDHLPLLAKFRLEL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9Q6S3-1", "uniprot_id": "A0A8M9Q6S3_DANRE", "id": "A0A8M9Q6S3-1", "name": "RNA 2',3'-cyclic phosphatase ANGEL1", "aln": "-----MIVSAMFYALYPLSRLLDRVSAAWQKPPPVHVNGREVWDGGGQQQQQTEDSLQRNSTERSAQLPQDKHTHTHHPQGTLVETLERARAEEELQKTLCDVSQ---MEGVLSETPLAGLEDTHNPQPVKNQAESDYVFSS---VAGKHSEISPHLTADAPSEADRCDGVSASSGGAALLFASRSPVFDLSALLSDTQQLQMDAEPIGWHFPVG-HGLAEMCYCPYVQFPDVSYYPAFQDQDNIEVMWRVWEDLSEPQSSDSADAS---------------------------------------PVFDFSVMSYNILAQDLLE---ANPHLYTHCAEDALRWENRLQAVLKELQIWQPDIVCLQEVQEDHFQEQMHPVLINMGYTC------IYKRRTGSKTDGCAVLYRGERFTQLSVSLLEFRRSE----CELLDRDNVGIVLLLQPTAGP----------------HHQFTPVCVANTHLLFNP--RRGDVKLAQLAIMFAEIHSVMQKC-------RSEGKSCELILCGDFNAVPRSPLWTLITTGELYYHGLPTWMVSGQTDLSYK-AHHNRLFSPLWPSSLGITDRCQYNTDTHTTASDGKQQYSHEFMCQLRFCEAACVRPADLELIPGVTDKTPD----------------LRDMFSLRFSPSLRHRLSLTSAYSHIHPETLTDLVTTLNSEGAAMVDYIFYSQRQKSGFNGGGE-------SAGGLKLLARLSLLSEAHLWSLRGLPNESFPSDHLSLLVKLQLSSADI-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B2RYM0-1", "uniprot_id": "ANGE1_RAT", "id": "B2RYM0-1", "name": "RNA 2',3'-cyclic phosphatase ANGEL1", "aln": "-----MIASCLYYLLLPAARLFRFLSDAFFT--------------------CRKNALLAKS--SSPQVEGNFAMAPRGPDQEECEGLLQQWREEGWNQTLSTASEGPLADKGLAESSLALLMDNSGEQDTASEDKWSSRQLSDLRAADNLDQPFPEVLGEEPLAEDEGPLWAAVPVQTGPQYAD-CAVLPMGAMA--AEQWEEDPAMVAWSIAPEPMPQEETSMWPFEGLEQLQ--PPPMEIPYHEILWREWEDFSTQPDAQGLEAGD-------------------------------------GPQFQFTLMSYNILAQDLMQ---QSSELYLHCHPDILNWNYRFANLMQEFQHWDPDILCLQEVQEDHYWEQLEPSLRMMGFTC------FYKRRTGCKTDGCAVCYKPTRFRLLCASPVEYFRPG----LELLNRDNVGLVLLLQPLVPEGLG-------------QVSVAPLCVANTHVLYNP--RRGDVKLAQMAILLAEVDKVAR---------LSDGSHCPIILCGDLNSVPDSPLYNFIRDGELQYNGMPAWKVSGQEDFSHQ-LYQRKLQAPLWPSSLGITDCCQYVTSCHPKRSE-RLKYGRDFLLRFRFCDLACQRPVGLVLMEGVTDTKPDRPAGWAECIFEEEISELEPVFPRTIG-TIQHCLHLTSVYTHFLPQHGRPEVTTMPLGLGMTVDYIFFSAESCENENRSDHRLD----RDGTLKLLGRLSLLSEEILWAANGLPNPFYSSDHLCLLASFGMEVTAP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6L8Q7-1", "uniprot_id": "PDE12_HUMAN", "id": "Q6L8Q7-1", "name": "2',5'-phosphodiesterase 12", "aln": "-MWRLPGARAALRVIRTAVEKLSRAEAGSQTAAG--------AMERAVVRCVPSEPKLSLSFALADGSHKNMQRDQSEPLGRVLSRIATNALKGHAKAAAAKKSRKS-----RPNASGGAACSGPGPEPAVFCEPVVKLYYREEAVAEDVLNVDAWQDGAVLQIGDVKYKVERNPPAFTELQLPRYIMAGFPVCPKLSLEFGDPASSLFRWYKEAKPGAAEPEVGVPSSLSPSSPSSSWTETDVEERVYTPSNADIGLRLKLHCTPGDGQRFGH--SRELESVCVVEAGPGTCTFDHRHLYTKKVTEDALIRTVSYNILADTYAQTEFSRTVLYPYCAPYALELDYRQNLIQKELTGYNADVICLQEVDRAVFSDSLVPALEAFGLEG------VFRIK---QHEGLATFYRKSKFSLLSQHDISFYEALE---SDPLHKELLEKLVLYPSAQEKVLQRSSVLQVSVLQSTKDSSKRICVANTHLYWHP--KGGYIRLIQMAVALAHIRHVSCD----------LYPGIPVIFCGDFNSTPSTGMYHFVINGSIPED-HEDWASNGEEERCNMS---------------------------------------------------------------------------------------------------LTHFFKLKSACG-------EPAYTNYVGGFHGCLDYIFIDLN--------------------ALEVEQVIPLPSHEEVTTHQALPSVSHPSDHIALVCDLKWK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03264-1", "uniprot_id": "NGL2_YEAST", "id": "Q03264-1", "name": "RNA exonuclease NGL2", "aln": "----------------------------------------------------------MTQDKEVKVVAPDVAPDQEVEINKSVKDAKHQTNDDSLLQHKKKGKKGK------KSKPIVTPEHIAKVRAEREVMRKAKRDAMLAQGVDPDCPPELHFIRRPFLSLHEAEPVTG---------------------------------------------------------------------------------------------------------------------------------------FRFKLMTYNCLAQALIR-----RKLFPDSG-DALKWYRRSKVLLNEFKYYNSDVICLQEIDHIQFQSFWKDEFSKLGYDG------QYYRN-ATKNHGVAIMWRRELFHQVDKMLIDYDKESSESISTRTTTNNVGLVLALKFSEKVLSN---------LGKKSSKKCGILIGTTHLFWHP--FGTYERTRQCYIVLKKMKEFMHRVNVLQNENDGDLSHWFPFFCGDFNSQPFDTPYLSMTSKPVHYRNRAKTVIGCSTSYKFS--KVRDGEEGADDEEGGNIEKYGKDQPESPVPEKFHANEEQSELVDKMAQLHNSLDMRAISLYS-------------------------------------VGYKNVHPENAGLDNDRGEPEISNWANTWRGLLDYLFYVKKWDPQSNCQEVETLGDFEKENKVKCRGFLRMPPGNEMTKHGQPHVGEYASDHLSMVCDLELQL----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A8JQX3-1", "uniprot_id": "NOCT_DROME", "id": "A8JQX3-1", "name": "Nocturnin", "aln": "MDQKTTGLRENYGHRRQPALGKAMPVTALLLNLESNPLDYSRNDIGAELLEDDDKPPQLFSVTDEPPSPNEEDYKPPNHHEDDGKLAGERHREIPCSNCLKTAPGHLIDRQSAINEMCQRLCGPECRRPQGLTLDGVRQDFLRQYEIAEAVAKTSAMTSTVQMKQRLAARKLEFEKEMEMDEQLGVASPRNDINLGQSSTVAATGMGEFEFEPPRDLLLYLVRMGSFNSAPKINNVDSQDDGLVLPSGLSTPALLQHVQQLRGGGIEQPSLLTRGFLKPLLADEDVADGLRCLKLNSVSRVCSAPVEGDDIRLLQWNILSQTLGQ----HNDGFVRCPEEALTWEHRKYLIVQEILQNQPDVICLQEVDHFKFLQTVLGSQNYAGIFFPKPDSPCLYIEQNNGPDGCAIFYKRDKLQLQGYDTRILEVWR-------VQSNQVAIAARLRMRSSG--------------------REFCVATTHLKARHGALLAKLRNEQGRDLIRFVKQFAGD--------------TPLLLCGDFNAEPVEPIYATILGCDLLRLGSAYADVKLDREEILH-------------PNADVGEFVAKSMKREP--------------------------------------------------------------------------PYTTWKIREEGEECHTIDYVFYTPDRLKIKNCLDFPAGEQIGKNRTPSFQY----PSDHFSLVCDFELLPPTENGKESGSGSGSDGENETEVEGSKHGSIQ---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : :* *:: : . * * : :*: ..*::****::. : * . .* * :: : : : . :..**: . : * : : . .:***:*: * : : : . . : : .. : : .:. : ", "identical_positions": 21, "similar_positions": 56, "identity": "2.69%" }, { "cls_id": "homologset.agr.SGD:S000004901", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7T6-1", "uniprot_id": "G3V7T6_RAT", "id": "G3V7T6-1", "name": "Splicing factor 3B subunit 1", "aln": "MAKIAKTHEDIEAQIREIQGKKAALD----EAQGVG-LDSTGYYDQEIYGGSDS----RFAGYVTSIAATELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYKKHRRTMIISPERLDPFADGGKTPDPKMNARTYMDVMREQHLTKEEREIRQQLAEKAKAG-ELKVVNGAAASQ---PPSK---RKR-RWDQTADQTPGATPKKLSSWDQAETP---GHTP-SLRWDETPGRAKGSETPGATP--GSKIWDPTPSHTPAGAATPGRGDTPGHATPGHGGATSSARKNRWDETPKTERDTPGHGSGWAETPRTDR-----GGDSIGETPTPGASKRKSRWDETP-----------ASQMGG--------------STPVLTPG-KTPIGTPAMNMATPTPGHIMSMTPEQLQAWRWEREIDERNRPLSDEELDAMFPEGYKVLPPPAGYVPIRTPARKLTATPTPLGG-MTGFHMQTEDRTMKSVNDQPSG-NLPFLKPDDIQYFDKLLVDVDESTLSPEEQKERKIMKLLLKIKNGTPPMRKAALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPYVHKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARAFAVVASALGIPSLLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGCAILPHLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAATPYGIESFDSVLKPLWKGIRQHRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFQSPDEEMKKIVLKVVKQCCGTDGVEANYIKTEILPPFFKHFWQHRMALDRRNYRQLVDTTVELANKVGAAEIISRIVDDLKDEAEQYRKMVMETIEKIMGNLGAADIDHKLEEQLIDGILYAFQEQTTEDSVMLNGFGTVVNALGKRVKPYLPQICGTVLWRLNNKSAKVRQQAADLISRTAVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMHKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEYVSAREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPALMNEYRVPELNVQNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGVYGFGCEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMLQYCLQGLFHPARKVRDVYWKIYNSIYIGSQDALIAHYPRIYNDDKNTYIRYELDYIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75533-1", "uniprot_id": "SF3B1_HUMAN", "id": "O75533-1", "name": "Splicing factor 3B subunit 1", "aln": "MAKIAKTHEDIEAQIREIQGKKAALD----EAQGVG-LDSTGYYDQEIYGGSDS----RFAGYVTSIAATELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYKKHRRTMIISPERLDPFADGGKTPDPKMNARTYMDVMREQHLTKEEREIRQQLAEKAKAG-ELKVVNGAAASQ---PPSK---RKR-RWDQTADQTPGATPKKLSSWDQAETP---GHTP-SLRWDETPGRAKGSETPGATP--GSKIWDPTPSHTPAGAATPGRGDTPGHATPGHGGATSSARKNRWDETPKTERDTPGHGSGWAETPRTDR-----GGDSIGETPTPGASKRKSRWDETP-----------ASQMGG--------------STPVLTPG-KTPIGTPAMNMATPTPGHIMSMTPEQLQAWRWEREIDERNRPLSDEELDAMFPEGYKVLPPPAGYVPIRTPARKLTATPTPLGG-MTGFHMQTEDRTMKSVNDQPSG-NLPFLKPDDIQYFDKLLVDVDESTLSPEEQKERKIMKLLLKIKNGTPPMRKAALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPYVHKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARAFAVVASALGIPSLLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGCAILPHLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAATPYGIESFDSVLKPLWKGIRQHRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFQSPDEEMKKIVLKVVKQCCGTDGVEANYIKTEILPPFFKHFWQHRMALDRRNYRQLVDTTVELANKVGAAEIISRIVDDLKDEAEQYRKMVMETIEKIMGNLGAADIDHKLEEQLIDGILYAFQEQTTEDSVMLNGFGTVVNALGKRVKPYLPQICGTVLWRLNNKSAKVRQQAADLISRTAVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMHKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEYVSAREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPALMNEYRVPELNVQNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGVYGFGCEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMLQYCLQGLFHPARKVRDVYWKIYNSIYIGSQDALIAHYPRIYNDDKNTYIRYELDYIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99NB9-1", "uniprot_id": "SF3B1_MOUSE", "id": "Q99NB9-1", "name": "Splicing factor 3B subunit 1", "aln": "MAKIAKTHEDIEAQIREIQGKKAALD----EAQGVG-LDSTGYYDQEIYGGSDS----RFAGYVTSIAATELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYKKHRRTMIISPERLDPFADGGKTPDPKMNARTYMDVMREQHLTKEEREIRQQLAEKAKAG-ELKVVNGAAASQ---PPSK---RKR-RWDQTADQTPGATPKKLSSWDQAETP---GHTP-SLRWDETPGRAKGSETPGATP--GSKIWDPTPSHTPAGAATPGRGDTPGHATPGHGGATSSARKNRWDETPKTERDTPGHGSGWAETPRTDR-----GGDSIGETPTPGASKRKSRWDETP-----------ASQMGG--------------STPVLTPG-KTPIGTPAMNMATPTPGHIMSMTPEQLQAWRWEREIDERNRPLSDEELDAMFPEGYKVLPPPAGYVPIRTPARKLTATPTPLGG-MTGFHMQTEDRTMKSVNDQPSG-NLPFLKPDDIQYFDKLLVDVDESTLSPEEQKERKIMKLLLKIKNGTPPMRKAALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPYVHKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARAFAVVASALGIPSLLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGCAILPHLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAATPYGIESFDSVLKPLWKGIRQHRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFQSPDEEMKKIVLKVVKQCCGTDGVEANYIKTEILPPFFKHFWQHRMALDRRNYRQLVDTTVELANKVGAAEIISRIVDDLKDEAEQYRKMVMETIEKIMGNLGAADIDHKLEEQLIDGILYAFQEQTTEDSVMLNGFGTVVNALGKRVKPYLPQICGTVLWRLNNKSAKVRQQAADLISRTAVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMHKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEYVSAREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPALMNEYRVPELNVQNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGVYGFGCEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMLQYCLQGLFHPARKVRDVYWKIYNSIYIGSQDALIAHYPRIYNDDKNTYIRYDLDYIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VPR5-1", "uniprot_id": "Q9VPR5_DROME", "id": "Q9VPR5-1", "name": "Splicing factor 3B subunit 1", "aln": "MENIPRTHEDIEAQISVIQEKKTELAKTTAAAAGVGLLDSGGFFDSDLYDDDAAKGKGRYEGYNTSIAANDAEEVDEDEDDGFPVP-QKRTTYTAPASVLKDVTQGKEDVDPMADRRRPTIADREDEYRQKRRHIIISPERADPFADGGKTPD--VGSRTYTDIMREQMLKGEESELRRRILEKTKEGTLVKTVTSSSTSNGDLPAPKDGGRKRGRWDQTVSDS--FIPAKMATPSSAATPTWEDKTPGDHRWDETPG-HKGSETPGATPGLGTRIWDATPAHAVT----------PGHETPGH---EKSARRNRWDETPKTERETPGH-SGWAETPKPDRTGSGGGAESISIESTPGASKRRSRWDETPSNATPAITPTNASAMTPNMTPSMTPHVTPGHATPMLTPGGSTPIGVKAMAMATPSAGALAAMTPEQLQAYRWEKEIDERNRPYTDEELDQIFPPGYKILPPPAGYVPLRTPGRKLMATPTPIAGTPAGFFIQVEDKNAKFMDNQPKGQNLPFMKPEDAQYFDKLLVDVNEDSLSPEELKERKIMKLLLTIKNGSPPMRKSALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRVLYKLDDLVRPYVHKILVVIEPLLIDEDHYARIEGREIISNLAKAAGLATMISTMRPDIDNIDEYVRNTTARAFAVVASALGIPSLLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGCAILPHLKALVEIIEHGLVDEQQKVRTITALAIAALAEAATPYGIESFDSVLKPLWKGIRTHRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFQSPDEEMKKIVLKVVKQCCATDGVEPQYIKEEILPHFFKFFWNHRMALDRRNYRQLVDTTVEIANKVGASEIINRVVDDLKDENEQYRKMVMETVEKIMGNLGAADIDSRLEEQLIDGILYAFQEQTTEDVVMLNGFGTIVNQLGKRVKPYLPQICGTILWRLNNKSAKVRQQAADLISRIAVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGPEYVSAREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAESCRPFTVLPALMNEYRVPELNVQNGVLKSLSFLFEYIGEMGKDYIYAVCPLLEDALMDRDLVHRQTACSAIKHMSLGVYGFGCEDALTHLLNYVWPNIFETSPHLVQAFMDSVDGLRVSLGPIKILQYTLQGLFHPARKVRDVYWKIYNSLYIGGQDALIAGYPRITNDPKNQYERYELDYTL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P49955-1", "uniprot_id": "SF3B1_YEAST", "id": "P49955-1", "name": "U2 snRNP component HSH155", "aln": "------------------------------------------------------------MSHPIQFVNANNSDKSHQLGGQYSIPQDLRENLQKEAARIGENE--KDVLQEKMETR--TVQNREDSYHKRRFDMKFEPD-----SD------------------------------TQTVTSSENTQ------------------------------------------------DAVVP----------------------------------------------------------------------------------------------------------------------RKRKSRWDVKG-----------------------------------------------------------------------------------------------YE--PPDESSTAVK------------------------ENSDSALVNVEGIH-DLMFFKPSDHKYFADVISKKPIDELNKDEKKERTLSMLLLKIKNGNTASRRTSMRILTDKAVTFGPEMIFNRLLPILLDRSLEDQERHLMIKTIDRVLYQLGDLTKPYVHKILVVAAPLLIDEDPMVRSTGQEIITNLSTVAGLKTILTVMRPDIENEDEYVRNVTSRAAAVVAKALGVNQLLPFINAACHSRKSWKARHTGIKIVQQIGILLGIGVLNHLTGLMSCIKDCLMDDHVPVRIVTAHTLSTLAENSYPYGIEVFNVVLEPLWKGIRSHRGKVLSSFLKAVGSMIPLMDPEYAGYYTTEAMRIIRREFDSPDDEMKKTILLVLQKCSAVESITPKFLREEIAPEFFQKFWVRRVALDRPLNKVVTYTTVTLAKKLGCSYTIDKLLTPLRDEAEPFRTMAVHAVTRTVNLLGTADLDERLETRLIDALLIAFQEQTNSDSIIFKGFGAVTVSLDIRMKPFLAPIVSTILNHLKHKTPLVRQHAADLCAILIPVIKNCHEFEMLNKLNIILYESLGEVYPEVLGSIINAMYCITSVMDLDKLQPPINQILPTLTPILRNKHRKVEVNTIKFVGLIGKLAPTYAPPKEWMRICFELLELLKSTNKEIRRSANATFGFIAEAIGPHDVLVALLNNLKVQERQLRVCTAVAIGIVAKVCGPYNVLPVIMNEYTTPETNVQNGVLKAMSFMFEYIGNMSKDYIYFITPLLEDALTDRDLVHRQTASNVITHLALNCSGTGHEDAFIHLMNLLIPNIFETSPHAIMRILEGLEALSQALGPGLFMNYIWAGLFHPAKNVRKAFWRVYNNMYVMYQDAMVPFYP-VTPDNNEEYI-EELDLVL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .:. : .: ..: .. .: : : .: : : .: : : * .: :***.*:::* : :.*: :* : : .. : .* .* **:**** . *: ** . ..:: *: :: : :* *:**.* :** .:: . . *. :* ***.: ***.****... *::::* :**** **. :**::**:*:. :********::*.***:**:*.**.:********* ******* .* *:***:**:..*** *:::.*****:* ******.*:** ****.***: .****::*.*:*:***:************.**:* .:* ** .*:. *:. *:*:: ** ::* ::::*** : ***** *: **:******* **** *::****:* :*****.***.*** *.* *: ***:***:**** :* *:::*...:.: .:::: ** * **: ** :*:**** : :. *** :*:*:*.: *.::: *:** * :*.*.:.:: : :. **:**:* :** :***.:* ******..* ::::***::. *. *:**:*. * .*:* :*::*:. ***:**** : *:*.*:* :::.:*.::*** *** ********:.*: .*..*:.: *: ***:::** *****:*:*.**: * *.:** *.. .. *...:**************: :* ***:: ***:**:********.:*********** ****:***.***: * *:.***.:**** .** ********::**:*****:*.***** : ******* **********. .: *::*. * * **:: **:* : **:****** : .: .::.* ::** :::* ******::**..:*::**.:*: ***::. ** : * :: * :** *", "identical_positions": 458, "similar_positions": 316, "identity": "33.68%" }, { "cls_id": "homologset.agr.SGD:S000004903", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NVP1-1", "uniprot_id": "DDX18_HUMAN", "id": "Q9NVP1-1", "name": "ATP-dependent RNA helicase DDX18", "aln": "MSHLPMKLLRKKIEKRNLKLRQRNLKFQGASNLTLSETQNGDVSEETMGSRKVKKSKQKPMNVGLSETQNGGMSQEAVGNIKVTKSPQKSTVLTNGEAAMQSS-NSESKKKKKKKRKMVNDAEPDTKKAKTENKGKSEEESAETTK------------ETENNVEKPDNDEDESEVPSLPLGLTG-AFEDTSFASLCNLVNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINIIVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTR-RQTMLFSATQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFLKKNRKKKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGFLRYLKQSKVPLSEFDFSWSKISDIQSQLEKLIEKNYFLHKSAQEAYKSYIRAYDSHSLKQIFNVNNLNLPQVALSFGFKVPPFVDLNVNSNEG-KQKKRGGGGGFGYQKTKKVEKSKIFKHISKKSSD-SRQFSH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K363-1", "uniprot_id": "DDX18_MOUSE", "id": "Q8K363-1", "name": "ATP-dependent RNA helicase DDX18", "aln": "MSQLQMKLLRRKIEKRNAKLRQRNLKLQETSDTSLSQPQNGDVPKETGKGGKVKKALKRSVPVDSAEAQSGGMPEETLENGKVKKSPQKLTTLANGEAAPTPPPDSEVKKKKKKKRKMANDAGPDTKKAKT-------EESAEACE------------EPEDDVKKAD----DSEVPSLPLGLTG-AFEDTSFASLSNLVNENTLKAIEEMGFKRMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPVIELIVKLKFMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEVQKLLNGINIIVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPAR-RQTMLFSATQTRKVEDLARISLKKEPLYVGVDDDKEVATVDGLEQGYVVCPSEKRFLLLFTFLKKNRKKKVMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGILLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGFLRYLKQSKVPLNQFDFSWSKVSDIQSQLEKLIEKNYFLHKSAQEAYKSYIRAYDSHSLKQIFNVNNLNLPQVALSFGFKVPPFVDLNVSSHDG-KLKKRGGGGGFGYQKTKKVEKSKIFKHISKKPAD-RRQFSH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VD51-1", "uniprot_id": "DDX18_DROME", "id": "Q9VD51-1", "name": "Probable ATP-dependent RNA helicase pitchoune", "aln": "MS-IREKLLMKKIVKR-EKMKKELSQKKGNKNAQKQEPPKQNGNKPS---KKPEKLSKKHVAKDEDDDLEEDFQEAPLPKKKQQKQPPKKQQIQVANSDSESD-DDEQEDEADEDSDLDEVAEVDEEDVDSGSEDDDQQEDEDEEEPVPAKKTKLLPNKSKAQNGKPAKDDEPFTVESSLAALDYRDSDDRSFASLKGAVSEATLRAIKEMGFTEMTEIQSKSLTPLLKGRDLVGAAQTGSGKTLAFLIPAVELINKLRFMPRNGTGVIIISPTRELSMQTFGVLKELMAHHHHTYGLVMGGSNRQVESEKLGKGINILVATPGRLLDHLQNSPDFLYKNLQCLIIDEVDRILEIGFEEELKQIINLLPKR-RQTMLFSATQTARIEALSKLALKSEPIYVGVHDNQDTATVDGLEQGYIVCPSEKRLLVLFTFLKKNRKKKVMVFFSSCMSVKYHHELFNYIDLPVTSIHGKQKQTKRTTTFFQFCNAESGILLCTDVAARGLDIPQVDWIVQYDPPDDPREYIHRVGRTARGSGTSGHALLLMRPEELGFLRYLKAAKVPLNEFEFSWQKIADIQLQLEKLIAKNYFLNQSAKEAFKSYVRAYDSHQLKQIFNVNTLDLQAVAKSFGFLVPPVVDLKVGAAKRERPEKRVGGGGFGFYKKMNEGSASKQRHFKQVNRDQAKKFMR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03532-1", "uniprot_id": "HAS1_YEAST", "id": "Q03532-1", "name": "ATP-dependent RNA helicase HAS1", "aln": "-------------------------------------------------------------------------------------------------MATPSN-------KRSRDSESTEEPVVDEKSTSK-------QNNAAPEG------------EQTTCVEK--------------------------FEELK--LSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYLKASKVPLNEYEFPENKIANVQSQLEKLIKSNYYLHQTAKDGYRSYLQAYASHSLKTVYQIDKLDLAKVAKSYGFPVPPKVNITIGASGKTPNTKR--------RKTHK-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ... . : . * :.... ::. : * * .* :.: **:**::***. **.:* ::: *** ***::.**:************.:**: .*:* ******:::::*****::* *** :*** .* :*:*:::**:** * :** :*:*:::*********:**: .*::***:.*:***.****::***:*::***::** . **:******** ::* *::::*: *:::.* : :*.*******:** *:**:*:**:***:*:***::**:*** ****: **:******* :****** ***.***:****: * *:************ ****:*:******::*********** *::*::: *:********* :****.:::*. .*::::* ****** .**:*:::*::.::**::** **.** :::::.*:* ** *:** *** *::.:.: ** *. : ", "identical_positions": 259, "similar_positions": 159, "identity": "37.7%" }, { "cls_id": "homologset.agr.SGD:S000004905", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UIK4-1", "uniprot_id": "DAPK2_HUMAN", "id": "Q9UIK4-1", "name": "Death-associated protein kinase 2", "aln": "-------MFQASMRSPNMEPFKQQK---------VEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSRE--------------EIEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEE-EATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPH------------------IKLIDFGLAHEIEDG--VEFKNIFGTPEFVAPEIVN--------------YEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQ-TSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNL---ENFRKQYVRRRWKLSFSIVSLCNHLTRSLMKK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VHLRPDE-------------------------DLRNCESD-----------------------------------------------------------------------------------------------------TEEDIAR--------------RKALHP----------------------------------------------RRR---SSTS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53355-1", "uniprot_id": "DAPK1_HUMAN", "id": "P53355-1", "name": "Death-associated protein kinase 1", "aln": "-----------------MTVFRQEN---------VDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSRE--------------DIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEE-EATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPR------------------IKIIDFGLAHKIDFG--NEFKNIFGTPEFVAPEIVN--------------YEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSN-TSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNM---EKFKKFAARKKWKQSVRLISLCQRLSRSFLSRSNMSVARSDDTLDEEDSFVMKAIIHAINDDNVPGLQHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGLLARLRKDTHRGLFIQQLRPTQNLQPRIKLKLFGHSGSGKTTLVESLKCGLLRSFFRRRRPRLSSTNSSRFPPSPLASKPTVSVSINNLYPGCENVSVRSRSMMFEPGLTKGMLEVFVAPTHHPHCSADDQSTKAIDIQNAYLNGVGDFSVWEFSGNPVYFCCYDYFAANDPTSIHVVVFSLEEPYEIQLNQVIFWLSFLKSLVPVEEPIAFGGKLKNPLQVVLVATHADIMNVPRPAGGEFGYDKDTSLLKEIRNRFGNDLHISNKLFVLDAGASGSKDMKVLRNHLQEIRSQIVSVCPPMTHLCEKIISTLPSWRKLNGPNQLMSLQQFVYDVQDQLNPLASEEDLRRIAQQLHSTGEINIMQSETVQDVLLLDPRWLCTNVLGKLLSVETPRALHHYRGRYTVEDIQRLVPDSDVEELLQILDAMDICARDLSSGTMVDVPALIKTDNLHRSWADEEDEVMVYGGVRIVPVEHLTPFPCGIFHKVQVNLCRWIHQQSTEGDADIRLWVNGCKLANRGAELLVLLVNHGQGIEVQVRGLETEKIKCCLLLDSVCSTIENVMATTLPGLLTVKHYLSPQQLREHHEPVMIYQPRDFFRAQTLKETSLTNTMGGYKESFSSIMCFGCHDVYSQASLGMDIHASDLNLLTRRKLSRLLDPPDPLGKDWCLLAMNLGLPDLVAKYNTSNGAPKDFLPSPLHALLREWTTYPESTVGTLMSKLRELGRRDAADFLLKASSVFKINLDGNGQEAYASSCNSGTSYNSISSVVSR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O43293-1", "uniprot_id": "DAPK3_HUMAN", "id": "O43293-1", "name": "Death-associated protein kinase 3", "aln": "-----------------MSTFRQED---------VEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSRE--------------EIEREVNILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTED-EATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPR------------------IKLIDFGIAHKIEAG--NEFKNIFGTPEFVAPEIVN--------------YEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSN-TSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKAIR-RRNVRGEDSGRKP---ERRRLKTTRLKEYTIKSHSSLPPNNSYADFER----------------------------------------------------------------------------------------------------------------------------------------------------------------------------FSKVLEEAAAAEEG------------------LRELQRSRRLCHED------------------------------------------------------------------------------------------------------VEALAAIYEEKE-----AWYREESDS----------------------------------------LGQDLRRLRQELLKTEALKRQAQEEAKG----------------------------------------------------------------------------------------ALLGTSGLKRRFSRLENRYEALAKQVASEMRFVQDLVRALE--------QEKLQGVECGLR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03533-1", "uniprot_id": "TDA1_YEAST", "id": "Q03533-1", "name": "Serine/threonine-protein kinase TDA1", "aln": "MTTASSSASQLQQRLPEEKPWPQLSGSNADAQTFKCKYVTNHNSLGDGNFSVVKECMNIHTKDLYAMKLIKKQTVKNKIQLIQREFDLLRSISEKIRDMEKKNEHSLDIFEGHHHILQLFDYFETADNIVLITQLCQKGDLYEKIVENQCLDLETQVTSYCACLVSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEYNTSKVNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFMAFGYTPFDCTTDDETLECISKCDYYVDEQMMHDPKYEQFWNFVQCCFTIDPAVRRSAKNLKQHPFIKDYFATSNSLNTKDTPNFSFHPTIRRVSSTASMHTLRSPSKSRKTTTLAYLNMDG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSSETSTAFSSKMD------------------LPDLYVDRTINSRERSLN------------------------------------------------------------------------------------------------RIRDTLKKTLSMTSLKPAGTFDYLHANK----------------------------------------NGTSLSSSKSGLVKKNSTFVLDPKPPKNS--------------------------------------------------------------------------------------LMNGCFSTTPESRSNFNTPKTLSRQGSSTSVKKYVNEVDLLLTPRTASMSSNDTTAINDYDTTNDKNPARKHAASFQVNVDDSDGDETMQI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . .. :.**.*:*::*::* : * ** *:***: . : :.** : :.* .: * ::: *.: :*. :::** :* *:*:: :.:::.* : :.*.: ::. : :**: *.* ***.**::: : : : : ***:* : : . .:*::.** .::*****: : * .*:*::**:**:: * :** *.:*** :: .* .::: : : . :*:: :. :. * : : .*.:*. . : : . : : :. . : : : . : ... ", "identical_positions": 67, "similar_positions": 128, "identity": "4.44%" }, { "cls_id": "homologset.agr.SGD:S000004906", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CR60-1", "uniprot_id": "GOT1B_MOUSE", "id": "Q9CR60-1", "name": "Vesicle transport protein GOT1B", "aln": "MISLTDTQKIGMGLTGFGVFFLFFGMILFFDKALLAIGNVLFVAGLAFVIGLERTFRFFFQRHKVKATGFFLGGVFVVLIGWPLIGMIFEIYGFFLLFRGFFPVVVGFIRRVPVLGSLLNLPGIRSFVDKVGESNNMV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3E0-1", "uniprot_id": "GOT1B_HUMAN", "id": "Q9Y3E0-1", "name": "Vesicle transport protein GOT1B", "aln": "MISLTDTQKIGMGLTGFGVFFLFFGMILFFDKALLAIGNVLFVAGLAFVIGLERTFRFFFQKHKMKATGFFLGGVFVVLIGWPLIGMIFEIYGFFLLFRGFFPVVVGFIRRVPVLGSLLNLPGIRSFVDKVGESNNMV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q59E43-1", "uniprot_id": "Q59E43_DROME", "id": "Q59E43-1", "name": "Vesicle transport protein GOT1B", "aln": "MIEISDLQKIGIGLAGFGIFFLFLGMLLLFDKGLLAIGNILFISGLACVIGVERTMRFFFQRHKVKGTTAFLGGIVIVLLGFPIFGMIIESYGFFALFSGFFPVAINFLGRVPVLGSLFNLPFIQKIVQKLGGDGNRTTV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9DCQ3-1", "uniprot_id": "GOT1A_MOUSE", "id": "Q9DCQ3-1", "name": "Vesicle transport protein GOT1A", "aln": "MISITEWQKIGVGITGFGVFFILFGILLYFDSVLLAFGNLLFLTGLSLIIGLRRTFAFFFQRHKLKGTSFFLGGVAIVLLRWPLLGMLLEAYGFISLFKGFFPVVFGFLG------SAFNIPFLSTLFQKLQGSSSSMV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZFB0-1", "uniprot_id": "D3ZFB0_RAT", "id": "D3ZFB0-1", "name": "", "aln": "-------MEIGVGITGFGVFFILFGILLYFDSVLLAFGNLLFLTGLSLIIGLRRTFSFFFQRHKLKGTSFFLGGVAIVLLRWPLLGMLLEAYGFVSLFKGFFPVVFGFLG------NAFNIPFLSALFQRLQGSSSSMV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZVE7-1", "uniprot_id": "GOT1A_HUMAN", "id": "Q6ZVE7-1", "name": "Vesicle transport protein GOT1A", "aln": "MISITEWQKIGVGITGFGIFFILFGTLLYFDSVLLAFGNLLFLTGLSLIIGLRKTFWFFFQRHKLKGTSFLLGGVVIVLLRWPLLGMFLETYGFFSLFKGFFPVAFGFLG------NVCNIPFLGALFRRLQG-TSSMV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03554-1", "uniprot_id": "GOT1_YEAST", "id": "Q03554-1", "name": "Protein transport protein GOT1", "aln": "-MWLTEAQKFGVAFTFGGFLFFLFGIFTFFDRALLALGNILFLIGVFLIIGSQKTYIFFTRPNKRRGSLFFLVGAFLILLKWTFLGFIIESLGIIGLFGDFFGVIVQFLRSMPIIGPILSHPAIAPIVDKLAGVRVLPV-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*:.:: *.:*:::* : ** ***:**:**: *: :** .:* ** : :* :.: :* * ::*: :.::*:::* *:. ** .** * . *: . * : :. :: ", "identical_positions": 33, "similar_positions": 46, "identity": "23.57%" }, { "cls_id": "homologset.agr.SGD:S000004907", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FWT5-1", "uniprot_id": "GATA_RAT", "id": "Q5FWT5-1", "name": "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "aln": "-------------MLGRTLREVSSALKQGHITPTELCKKCLSLIKKTKYLNAYITVSEEVALKQAEESEKRYKQGQSLGDLDGIPVAVKDNFSTSGIETTCASNMLKGYLPPYNATVVQRLLDQGALLMGKTNLDEFAMGSGSTDGVFGPVKNPWTYSKQYRERSRQD---AQEDSHWLITGGSSGGSAAAVAAFTCFAALGSDTGGSTRNPAAHCGTVGFKPSYGLVSRHGLIPLVNSMDVPGIFTRCVDDTAIVLGVLAGHDPKDSTTVNDPV-KPTTLPSV--PDVSGLCIGIPKEYLVPELSSEIRSLWSQAADLFEAEGARVIEVCLPHTCYSIVCYHVLCTSEVASNMARFDGLQYGHRSAVDMSSTEALYAATRQEGFNDVVKGRILSGNFFLLKENYENYFVKAQKVRRLIVNDFVNVFGS------------GVDVLLTPTTLTQAVPYLEFIKEDNRT--RSAQDDIFTQAVNMAGLPAVNVPVALSSQGLPIGLQLIGRAFCDQQLLTVAKWFEKQVQFPVIQLQDLMDDGSLVPENGKLTSGSLTQ--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CZN8-1", "uniprot_id": "GATA_MOUSE", "id": "Q9CZN8-1", "name": "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "aln": "-------------MLGRTLREVSAALKQGQVTPTELCKNCLSLIKKTKYLNAYITVSEEVALKQAEESEKRYKQGQSLGDLDGIPVAVKDNFSTTGIETTCASNMLKGYVPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGVFGPVRNPWTYSKQYRERSRQD---AGDDSHWLITGGSSGGSAAAVAAFTCFAALGSDTGGSTRNPAAHCGIVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDTAIVLGTLAGHDPKDSTTVRNPA-QPASVPGG--MDVSRLCIGIPKEYLVPELSSEVRSLWSQAADLFESEGAKVIEVSLPHTCYSIVCYHVLCTSEVASNMARFDGLQYGHRSGVDVS-TEAMYAATRQEGFNDVVRGRILSGNFFLLKENYENYFVKAQKVRRLIVKDFVDVFES------------GVDVLLTPTTLTEAVPYLEFIKEDNRT--RSAQDDIFTQAVNMAGLPAVSVPVALSNQGLPIGLQLIGRAFCDQQLLTVAKWFEKQVQFPVIQLQGLMDDGSLVLENGKLTSASLTQR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0R6-1", "uniprot_id": "GATA_HUMAN", "id": "Q9H0R6-1", "name": "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "aln": "-------------MLGRSLREVSAALKQGQITPTELCQKCLSLIKKTKFLNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPIAVKDNFSTSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGVFGPVKNPWSYSKQYREKRKQNPHSENEDSDWLITGGSSGGSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDAAIVLGALAGPDPRDSTTVHEPINKPFMLPSL--ADVSKLCIGIPKEYLVPELSSEVQSLWSKAADLFESEGAKVIEVSLPHTSYSIVCYHVLCTSEVASNMARFDGLQYGHRCDIDVS-TEAMYAATRREGFNDVVRGRILSGNFFLLKENYENYFVKAQKVRRLIANDFVNAFNS------------GVDVLLTPTTLSEAVPYLEFIKEDNRT--RSAQDDIFTQAVNMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQQLLTVAKWFEKQVQFPVIQLQELMDDCSAVLENEKLASVSLKQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QAJ4-1", "uniprot_id": "GATA_DANRE", "id": "F1QAJ4-1", "name": "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "aln": "MSASSAARRPVEAMLGLSIREVSQALRDGKVSATELCRKCINQIQRTRYLNAYITIAEETAMEQAERADKRLRTGKTLGPLDGIPFSVKDNFCTENIKTTCASNMLKGYVPPFSATVVQKLLDQGAVLVGKTNLDEFAMGAGSTDGAFGPVRNPWSYAAPYREQSAED-----PDSDWTITGGSSGGSAAAVASLSSFLALGSDTGGSTRNPGSLCGVVALKPSYGLLSRHGLIPLVNSMDVPGIMTRSVHDAATVLRILQGRDERDSTTVQAPN-TPPSLPEH--FDMRKICVGIPKEYHAPGLSEDTLAQWSRVADIFENAGARVKEVSLPHTPYSIVCYHVLCCCEVASNMARFDGLEYGHRSAVDSS-TDAMYATTRHEGFNNVVRRRILSGNYFLLKSNYERYFVKAQQMRRLIAEDFKKVFSS------------GIDVLLTPTTLSDAARYADFITEDNRT--RSAQEDVFTQPVNMAGLPAVTVPTALSQRGLPIGLQLIGQTLQDWKLLTIAHWMEKQLHFPMIRFHRDLNENERE-QNRSIRERTHTVGS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VE09-1", "uniprot_id": "GATA_DROME", "id": "Q9VE09-1", "name": "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "aln": "----------MRRHLQWSIKQLTASYSDGQLSPRRVTEDALQDALRWKTLNAFVRLTPEQAGQQAQDAEQRYKLRQPISDLDGVTIAIKDNFCTKDVHTTCASRMLQDFVPPYDATVCSRLKQAGAVILGKTNMDQFAMGAGTVDSLYGPTKNIWS------EDLNKD--------HWRIAGGSSGGSASAVAAGLCYAAIGSDTGGSTRNPASYCGVVGLKPTYGLVSRHGLIPLVNSMDVPGIFARSVSDCVAVLNTVAGPDKLDSTTIRQPF-TRLHLPEVGQIDLSTVRIGIPKEYHCHGLSAEVLETWSKVADLLECSGASVRQVSLPNTAASIFVYTILNQCEVASNMARYDGIEYGHRATDERS-TEQLYALSRAEGFNDVVKTRILTGNFLLLKKNYDHYFEKALRVRRLIAEDFARVFDSS-------AKEERVDILLTPTTLTEAPLYKDFASLTNRD--QCAVQDFCTQPANMAGIPAVSIPIRLSQAGLPLSLQLMSNSLNEQLLLTVARWIEAQVEFDSLEHSQQYKASL-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03557-1", "uniprot_id": "GATA_YEAST", "id": "Q03557-1", "name": "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "aln": "------------MPLKRSLKESIERLSSFQS-----------------KYNIFTSINPSPYSITNKKGTKET--------LTGCVASIKDNIVTKDFPTTCASHILENFKSPFDATVVKLLKQAGVHILGKTNLDEFGMGSGGVHSIRGPVINPLYPHE-----------------DKKIMGGSSSGAAASVACDLVDFALGTDTGGSVRLPACYGSVLGFKPSYGRLSRFGVIAYSQSLDTVGILSKKINVLRKVFHTLDKYDMKDPTSLSVELRELIEGNKK---VRRPLKVGIVKEFSHESMPIGFHRLYLSLLEKLINLGLEIYPVSIPSVKNCLPIYYTLSPAEAASNLSRYDGIRYGYRDSELDIKDGILFAPTR-SKFGTEVKNRIILGNYNLCSDAFKNNFIKAEKLRVNLIDEFDGIFRFPNVLTNSKGNPDGLDLLIVPTSSKLPGSIRDFEEEEAKSPANSYINDVFTVPMSLAGLPSLSMPLKEKT---PIGLQVVGQYGDDSTVLDFVESIS-----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :::: . : * : : . : . :. * * ::***: * .. *****.:*:.: .*:.*** . * : *. ::****:*:*.**:* ... **. * . * ****.*:*::*:. *:*:*****.* *.. . :.:**:** :**.*:*. :*:*. **::: : *: : * *.*:: : :** **: :. : : : * : *.:* . .: * * .*.***::*:**:.**:* ::* :* . *. *: **: **: * .. :.. * ** ::* : .:* * :*:*:.**: . . :* : .. :*. * . .:**:*::.:* . *:.**.:.. : :* ... :. ", "identical_positions": 114, "similar_positions": 147, "identity": "20.36%" }, { "cls_id": "homologset.agr.SGD:S000004908", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYH5-1", "uniprot_id": "DCTN2_RAT", "id": "Q6AYH5-1", "name": "Dynactin subunit 2", "aln": "-----MADP----KYADLPGIARNEPDVYETSDLPEDDQAEFD--AEELSSTSVEHIIVNPNAAYDKFKDKRVGTKGLDFSDRIGKTKRTGYES---GDYEMLGEGLGVKETPQQKYQRLLHEVQELTTEVEKIKTTVKESATEEKLTPVVLAKQLAALKQQLVASHLEKLLGPDAAINLADPDGALAKRLLLQLEATKSSKGSSG--GKSTGGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELEATVRCDQDAQNPLSAGLQGACLMETVELLQAKVNALDLAVLDQVEARLQSVLGKVNEIA---KHKASVEDADTQNKVHQLYETIQRWSPVASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMMASSLKDNTALLTQVQTTMRENLATVEGNFASIDARMKKLGK--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99KJ8-1", "uniprot_id": "DCTN2_MOUSE", "id": "Q99KJ8-1", "name": "Dynactin subunit 2", "aln": "-----MADP----KYADLPGIARNEPDVYETSDLPEDDQAEFD--AEELSSTSVEHIIVNPNAAYDKFKDKRVGTKGLDFSDRIGKTKRTGYES---GDYEMLGEGLGVKETPQQKYQRLLHEVQELTTEVEKIKTTVKESATEEKLTPVVLAKQLAALKQQLVASHLEKLLGPDAAINLADPDGALAKRLLLQLEATKSSKGSSG--GKATAGAPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELEATVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEARLQSVLGKVNEIA---KHKASVEDADTQNKVHQLYETIQRWSPVASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMMASSLKDNTALLTQVQTTMRENLATVEGNFASIDARMKRLGK--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13561-1", "uniprot_id": "DCTN2_HUMAN", "id": "Q13561-1", "name": "Dynactin subunit 2", "aln": "-----MADP----KYADLPGIARNEPDVYETSDLPEDDQAEFD--AEELTSTSVEHIIVNPNAAYDKFKDKRVGTKGLDFSDRIGKTKRTGYES---GEYEMLGEGLGVKETPQQKYQRLLHEVQELTTEVEKIKTTVKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGALAKRLLLQLEATKNSKGGSG--GKTTG-TPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEARLQSVLGKVNEIA---KHKASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMKKLGK--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T3H1-1", "uniprot_id": "DCTN2_DANRE", "id": "Q7T3H1-1", "name": "Dynactin subunit 2", "aln": "-----MADP----KYANLPGIASNEPDVYETSDLPEDDQAQFESELEELCSDSVERIVVNPNAAYDKFKDKHVSAKSLDFSDRISKNRRVGYES---GDYELLAEGCGVKETPQQKYQRLVNEIHELCQDVEKIQTSTKESGAEERLTPVALAQQAAQLKQQLVSAHLDSLLGPDAHINLTDPDGALAKRLLTQLEVARGVRSGAGADGKTAAPKGPDG-VILYELHSRPEQEKFTESAKVAELERRLAELETAVGSGSDKRGPLSSGVQGSSLTETLELLQARVSALDAATLDQVEARLQSVLGKMNEIA---KHKATMEDAETQSKVSQLYDVVQKWDAMATSLPQVVRRLTAVRELHEQAMQFGQLLTHLDTTQQMINNSLKDNSTLLTQVQQTMKENLLAVEENFSALDQRMKKLNK--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7K2D2-1", "uniprot_id": "DCTN2_DROME", "id": "Q7K2D2-1", "name": "Dynactin subunit 2", "aln": "-----MADP----KFQNLPGIAYDQPDVYETPDDPELDTSDYYE--EEPENEAIERLHISPSVAHKRFSGATVEGS-VDFTDRIGRRMCRGYDTRGSSDYELVGQ--GEKETPVQKCQRLQIEMNELLNEVAALQVDRK-VADEEKQSYDAVATVISTARKVLESLKLEQVLG-----KEQTPGSKQVKALISQVEEFKQS-------GVLTAIPTPGT--------------DLAATARVASLEQRISQLEKVLGAQPDKLSRLTAATNTTNVLEAVRHLSTKAALIQPDKLDTIEQRLTSLAGKMDAIAE--KSSGSAQDAKRDQKITELYDIAKRTEPVVEILPHVIERMQALEALHKYANNFAKIIAEIEQKQGTITTSLVNNKELLHSVQETFAQNLETINSKVAKVEQRVAAISSAK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36224-1", "uniprot_id": "JNM1_YEAST", "id": "P36224-1", "name": "Nuclear migration protein JNM1", "aln": "MNVIDLSDPAINVDYDSLIGIDNEESQEIFENEVKEDGQQEEQ----EEASSRKDGLIVEP--------GRDVESLRRAIRDQLLFKIHRQNQSDCADARKLSND--EEDESRQQKLERIREELEELK--IENLTSEMQTEIKELCEIQSKLATESSSRLTNLRKKLLETYEG---------QDTVILPNIILDTSNIKRLQ-------------------------------KLDQKISLMERFVGIPEALEAEEDRKSVHSKVNELYRSIQLLQGDDKAEGKLQKFRDRLVELNEEFENSLLGKKIQQDLRLKDDTVSKLVMPENKVKEINSMYSMFKQYQDSLPLLAERMKSLNKMNNRVIEVYETTKGLDSQITSIQEQGKVWLKALNELDKKFDEQEVKIRENMEQIRRKIDTLEDEALQRNSK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::** .: .* ** ::.: : * . : * . : : :.* . * : *:: :: . :: : .*: ** :*: *:.** : : : * :* : * *: * . :: : . : .: : . :.: . . . :. . : : . : : :: * *: ** * . : . :.*: :: . . . ** : .*: ::. ::: . :. : :: : . * .:: .: :: :. :. : :: : . ", "identical_positions": 32, "similar_positions": 110, "identity": "7.46%" }, { "cls_id": "homologset.agr.SGD:S000004911", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A2H2-1", "uniprot_id": "SPTC1_RAT", "id": "D4A2H2-1", "name": "Serine palmitoyltransferase 1", "aln": "--------------------------------MATVAEQWVLVEMVQALYEAPAYHLILEGILILWIIRLVFSKTYKLQ----ERSDLTAKEKEELIEEWQPEPLVPPVSRNHP----ALNYNIVSGPPTHNIVVNGK-------ECVNFASFNFLGLLANPRVKAAAFASLKKYGVGTCGPRGFYGTFDVHLDLEERLAKFMKTEEAIIYSYGFSTIASAIPAYSKRGDIVFVDSAACFAIQKGLQASRSDIKLFKHNDVADLERLLKEQEIEDQKNPRKARVTRRFIVAEGLYMNTGTICPLPELVRLKYKYKARIFLEESLSFGVLGEHGRGVTEHYGIS-IDDIDLISANMENALASVGGFCCGRSFVVDHQRLSGQGYCFSASLPPLLAAAAIEALNIMEENPGIFAVLKKKCQTIHKSLQGVSGLK----VVGESLCPALHLQLEESTGSR-----------------------------ERDMKLLQEIVEQCMN-KGIALTQARYLDKEEKCLPPPSIRVVVTVEQTDEELQRAAATIREAAQAVLL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35704-1", "uniprot_id": "SPTC1_MOUSE", "id": "O35704-1", "name": "Serine palmitoyltransferase 1", "aln": "--------------------------------MATVAEQWVLVEMVQALYEAPAYHLILEGILILWIIRLVFSKTYKLQ----ERSDLTAKEKEELIEEWQPEPLVPPVSKNHP----ALNYNIVSGPPTHNIVVNGK-------ECVNFASFNFLGLLANPRVKATAFSSLKKYGVGTCGPRGFYGTFDVHLDLEERLAKFMKTEEAIIYSYGFSTIASAIPAYSKRGDIIFVDSAACFAIQKGLQASRSDIKLFKHNDVADLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTICPLPELVKLKYKYKARIFLEESLSFGVLGEHGRGVTEHYGIS-IDDIDLISANMENALASVGGFCCGRSFVVDHQRLSGQGYCFSASLPPLLAAAAIEALNIMEENPDIFAVLKKKCQNIHKSLQGVSGLK----VVGESLSPALHLQLEESTGSR-----------------------------EKDVKLLQAIVDQCMD-KGIALTQARYLDKEEKCLPPPSIRVVVTVEQTEEELQRAASTIREAAQAVLL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15269-1", "uniprot_id": "SPTC1_HUMAN", "id": "O15269-1", "name": "Serine palmitoyltransferase 1", "aln": "--------------------------------MATATEQWVLVEMVQALYEAPAYHLILEGILILWIIRLLFSKTYKLQ----ERSDLTVKEKEELIEEWQPEPLVPPVPKDHP----ALNYNIVSGPPSHKTVVNGK-------ECINFASFNFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEDRLAKFMKTEEAIIYSYGFATIASAIPAYSKRGDIVFVDRAACFAIQKGLQASRSDIKLFKHNDMADLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTICPLPELVKLKYKYKARIFLEESLSFGVLGEHGRGVTEHYGIN-IDDIDLISANMENALASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPLLAAAAIEALNIMEENPGIFAVLKEKCGQIHKALQGISGLK----VVGESLSPAFHLQLEESTGSR-----------------------------EQDVRLLQEIVDQCMN-RSIALTQARYLEKEEKCLPPPSIRVVVTVEQTEEELERAASTIKEVAQAVLL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25045-1", "uniprot_id": "SPTC1_YEAST", "id": "P25045-1", "name": "Serine palmitoyltransferase 1", "aln": "MAHIPEVLPKSIPIPAFIVTTSSYLWYYFNLVLTQIPGGQFIVSYIKKSHHDDPYRTTVEIGLILYGIIYYLSKPQQKKSLQAQKPNLSPQEIDALIEDWEPEPLVDPSATDEQSWRVAKTPVTMEMPIQNHITITRNNLQEKYTNVFNLASNNFLQLSATEPVKEVVKTTIKNYGVGACGPAGFYGNQDVHYTLEYDLAQFFGTQGSVLYGQDFCAAPSVLPAFTKRGDVIVADDQVSLPVQNALQLSRSTVYYFNHNDMNSLECLLN-ELTEQEKLEKLPAIPRKFIVTEGIFHNSGDLAPLPELTKLKNKYKFRLFVDETFSIGVLGATGRGLSEHFNMDRATAIDITVGSMATALGSTGGFVLGDSVMCLHQRIGSNAYCFSACLPAYTVTSVSKVLKLMDSNNDAVQTLQKLSKSLHDSFASDDSLRSYVIVTSSPVSAVLHLQLTPAYRSRKFGYTCEQLFETMSALQKKSQTNKFIEPYEEEEKFLQSIVDHALINYNVLITRNTIVLKQETLPIVPSLKICCNAAMSPEELKNACESVKQSILACCQESNK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . .:*. :: :. .*: :* ***: * :**. : : ::.:*: :* : ***:*:***** * . :. * . :. * :: .:. : : .*:** *** * . ** .. :::*:****:*** ****. *** ** **:*: *: :::*. .*.: .*.:**::****::..* ..:.:*:.** *** : *:***: .** **: : *::* : . :.*:***.**:: *:* :.*****.:** *** *:*::*::*:**** ***::**:.:. **: ..* .**.* *** * *.: ***:..:.*****.**. .::. :.*::*:.* . . .*:: . :*.:: . ..*: *....:...:**** : ** *.: ::** **::.: .: :*: : *:*. **::: .. : ***:.*. :::: * ", "identical_positions": 159, "similar_positions": 186, "identity": "28.44%" }, { "cls_id": "homologset.agr.SGD:S000004912", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P16675-1", "uniprot_id": "PPGB_MOUSE", "id": "P16675-1", "name": "Lysosomal protective protein", "aln": "----------------------------------------------------------------MPGTALSPLLLLLLLSWASRNEAAPDQDEIDCLPG-------------------LAKQPSFRQYSGYLRASD--SKHFHYWFVESQNDPKNSPVVLWLNGGPGCSSLDGLLTEHGPFLIQPDGVTLEYNPYAWNLIANVLYIESPAGVGFSY-SDDKMYVTNDTEVAENNYEALKDFFRLFPEYKDN--KLFLTGESYAGIYIPTLA--VLVMQDPSMN-----LQGLAVGNGLASYEQNDNSLVYFAYYHGLLGNRLWTSLQTHCCAQNKCNFYDNKDPECVNNLLEVSRIVGKSGLNIYNLYAPCAGGVPGRHRYE-DTLVVQDFGNIFTRLPLKRRFPEALMR-SGDKVRLDPPCTNTTAPSNYLNNPYVRKALHIPESLPRWDMCNFLVNLQYRRLYQSMNSQYLKLLSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVDYGES--GEQVAGFVKECSHITFLTIKGAGHMVPTDKPRAAFTMFSRFLNKEPY-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ARV9-1", "uniprot_id": "A0A8I6ARV9_RAT", "id": "A0A8I6ARV9-1", "name": "Carboxypeptidase", "aln": "----------------------------------------------MPGLVGSDRVSVAGSWTGMPRAALSPLLLLLLLSWASRDEAAPDQDEIDCLPG-------------------LAKQPSFRQYSGYLKASD--SKHFHYWFVESQNDPKNSPVVLWLNGGPGCSSLDGLLTEHGPFLIQPDGVTLEYNPYSWNLIANMLYIESPAGVGFSY-SDDKMYVTNDTEVAENNYQALKDFYHLFPEYKDN--KLFLTGESYAGIYIPTLA--VLVMQDPSMN-----LQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWTSLQTHCCSQNKCNFYDNKDPDCVNNLQEVSRIVGKSGLNIYNLYAPCAGGVPGRDRSE-DTLVVQDFGNIFTRLPLKRRFPEALLLRSGDKVRLDPPCTNTTAPSTYLNNPYVRKALHIPESLPRWDMCNLMVNLQYRRLYESMNSQYLKLLSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVDYGES--GEQVAGFVKECSHITFLTIKGAGHMVPTDKPRAAFTMFSRFLNKEPY-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10619-1", "uniprot_id": "PPGB_HUMAN", "id": "P10619-1", "name": "Lysosomal protective protein", "aln": "-----------------------------------------------------------MIRAAPPPLFLLLLLLLLLVSWASRGEAAPDQDEIQRLPG-------------------LAKQPSFRQYSGYLKGSG--SKHLHYWFVESQKDPENSPVVLWLNGGPGCSSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSY-SDDKFYATNDTEVAQSNFEALQDFFRLFPEYKNN--KLFLTGESYAGIYIPTLA--VLVMQDPSMN-----LQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLR-SGDKVRMDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDS--GEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00729-1", "uniprot_id": "CBPY_YEAST", "id": "P00729-1", "name": "Carboxypeptidase Y", "aln": "MKAFTSLLCGLGLSTTLAKAISLQRPLGLDKDVLLQAAEKFGLDLDLDHLLKELDSNVLDAWAQIEHLYPNQVMSLETSTKPKFPEAIKTKKDWDFVVKNDAIENYQLRVNKIKDPKILGIDPNVTQYTGYLDVEDE-DKHFFFWTFESRNDPAKDPVILWLNGGPGCSSLTGLFFELGPSSIGPDLKPIG-NPYSWNSNATVIFLDQPVNVGFSY-SGS-SGVSNTVAAGKDVYNFLELFFDQFPEYVNKGQDFHIAGESYAGHYIPVFASEILSHKDRNFN-----LTSVLIGNGLT------DPLTQYNYYEPMACG---EGGEPSVLPSEECSAMEDSLERCLGLIESCYDSQSVWSCVPATIYCNNAQLAP------------------------YQRTGRNVYDIRKDCEGGNLCYPTLQDIDDYLNQDYVKEAVGAEVDHYESCNFDINRNFLFAGDWMKPYHTAVTDLLNQDLPILVYAGDKDFICNWLGNKAWTDVLPWKYDEEFASQKVRNWTASITDEVAGEVKSYKHFTYLRVFNGGHMVPFDVPENALSMVNEWIHGGFSL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VDT5-1", "uniprot_id": "Q9VDT5_DROME", "id": "Q9VDT5-1", "name": "Carboxypeptidase", "aln": "--MKTATHCAFLIIATIVAISGAKG-------------------VEGERPYRRSFINPYPRYQFFDDGVDPGEPLFLTPLINNASMSKQEVQKLARVVG--------------------SQFHGVESYSGYLTVDPGFKSNMFFWYFPAEQEPEYAPVVLWLQGGPGASSLFGLFTENGPLELDGHG-KLQKRNYTWSKTHNLIYIDNPVGTGFSFTENDAGYATNEKDVGRNLHEAVMQLYELFEWSNSS--GFWVTGESYAGKYVPALAYHIHKVQNAIETRVYVPLKGVAIGNGLS------DPLHQLKYGDYLYQLGLIDEHGLQSFHDAEAKGAECIKSHDMECAFDVFDSLINGDLTNGSLFSNLTG---------------------------YNWYYNYLKTHDDDGAN----------LGEFLQAGATRRAIHVGNKTFHDLDKENKVELHLKKDIMDSVAPWIAELLAH-YTVCIYSGQLDIIVAYPLTRNYLNQLKFPGSDKYKVAPREVWRVG--KEVAGYVKHAGHLVEIMVRNAGHMAPHDQPKWLYMMIDHLTHYKH--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : .. : . .. .*:*** . ..::.:* . :.::* **:***:****.*** **: * ** : . : . *:*. .:::::.*...***: ... .:* .... .: : :: * .. : ::****** *:*.:* : :: . * .: :****: :.* * . : . :.. : : . . .::. : . . : * . :*: .:.*: . . : :: . : * : : :* *: *: : . : : * . : .::** ** *:. : : ..***.* * * *... : ", "identical_positions": 67, "similar_positions": 133, "identity": "11.67%" }, { "cls_id": "homologset.agr.SGD:S000004915", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35433-1", "uniprot_id": "PUR1_RAT", "id": "P35433-1", "name": "Amidophosphoribosyltransferase", "aln": "-----------------------------------MELEES-------GIREECGVFGCIASGDWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPKFRVHKGMGLVNHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVAHNGELVNAARLRKKLLRHGIG-LSTSSDSEMITQLLAYTPPQEQD---DTPDWVARIKNLMKEAPAAYSLVIMHR-DVIYAVRDPYGNRPLCIGRLMPVSDINDKEKKSSETEGWVVSSESCSFLSIGARYCHEVKPGEIVEISRHGVR-TLDIIPRSNGDPVAFCIFEYVYFARPDSMFEDQMVYTVRYRCG-----QQLAVEAPVEADLVSTVPESATPAALGYATKCGLPYVEVLCKNRYVGRTFIQPNMRLRQLGVAKKFGVLSDNFKGKRIVLIDDSIVRGNTISPIIKLLKESGAKEVHIRVASPPIKHPCFMGINIPTKEELIANKPEFEYLAEYLGANSVVYLSVEGLVSSVQQEIKFKKQK-VKKRDITIQENGNGLEYFEKTGHCTACLTGQYP----VDLEW----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CIH9-1", "uniprot_id": "PUR1_MOUSE", "id": "Q8CIH9-1", "name": "Amidophosphoribosyltransferase", "aln": "-----------------------------------MELEEL-------GIREECGVFGCIASGDWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSAVPKFRVHKGMGLVNHVFTEDNLKKLYDSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVAHNGELVNAARLRKKLLRQGIG-LSTSSDSEMITQLLAYTPPQEKD---DAPDWVARIKNLMKEAPAAYSLVIMHR-DFIYAVRDPYGNRPLCIGRLMPVSDVNDKEKKSSETEGWVVSSESCSFLSIGARYCHEVKPGEIVEISRHGIR-TLDIIPRSNGDPVAFCIFEYVYFARPDSMFEDQMVYTVRYRCG-----QQLAIEAPVEADLVSTVPESATPAALGYATKCGLPYVEVLCKNRYVGRTFIQPNMRLRQLGVAKKFGVLSDNFKGKRIVLIDDSIVRGNTISPIIKLLKESGAKEVHIRVASPPIKYPCFMGINIPTKEELIANKPEFDCLAEYLGANSVVYLSVEGLVSSVQQEIKFKKQK-VKKHDIAIQENGNGLEYFEKTGHCTACLTGQYP----VELEW----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06203-1", "uniprot_id": "PUR1_HUMAN", "id": "Q06203-1", "name": "Amidophosphoribosyltransferase", "aln": "-----------------------------------MELEEL-------GIREECGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPTFKSHKGMGLVNHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVAHNGELVNAARLRKKLLRHGIG-LSTSSDSEMITQLLAYTPPQEQD---DTPDWVARIKNLMKEAPTAYSLLIMHR-DVIYAVRDPYGNRPLCIGRLIPVSDINDKEKKTSETEGWVVSSESCSFLSIGARYYREVLPGEIVEISRHNVQ-TLDIISRSEGNPVAFCIFEYVYFARPDSMFEDQMVYTVRYRCG-----QQLAIEAPVDADLVSTVPESATPAALAYAGKCGLPYVEVLCKNRYVGRTFIQPNMRLRQLGVAKKFGVLSDNFKGKRIVLVDDSIVRGNTISPIIKLLKESGAKEVHIRVASPPIKYPCFMGINIPTKEELIANKPEFDHLAEYLGANSVVYLSVEGLVSSVQEGIKFKKQK-EKKHDIMIQENGNGLECFEKSGHCTACLTGKYP----VELEW----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27601-1", "uniprot_id": "PUR1_DROME", "id": "Q27601-1", "name": "Amidophosphoribosyltransferase", "aln": "MSAPQQQQQSQQKQQQHVRVVEQQQVEPAEAVTSSMESESISASKELTGLTHECGVFGAIACGDWPTQMDIAHVICLGLVALQHRGQESAGIATSEGKCSKNFNVHKGMGMISTLFNDDSMKKLRG-NLGIGHTRYSTAGGSGVVNCQPFEVHTTHGALALAHNGELVNNESLRREVLARGVG-LSTHSDSELIAQSLCCAPEDVSEL--DGPNWPARIRHFMMLAPLSYSLVIMLK-DKIYAVRDTYGNRPLCIGKIVPINAGHGNNLDTP-ADGWVVSSESCGFLSIGARYVREVEPGEIVELSRSGYR-TVDIVERPDFKRMAFCIFEYVYFARGDSIFEGQMVYTVRLQCG-----RQLWREAPVEADIVSSVPESGTAAAHGYARESGIEFAEVLCRNRYVGRTFIQPSTRLRQLGVAKKFGALSENVAGKRLVLIDDSIVRGNTIGPIIKLLRDAGAREVHIRIASPPLQYPCYMGINIPTREELIANKLNPDQLARHVGADSLAYLSVEGLVEAVQLKHRDAGDS-KSKG----------------TGHCTACLTGEYPGGLPDELSW----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04046-1", "uniprot_id": "PUR1_YEAST", "id": "P04046-1", "name": "Amidophosphoribosyltransferase", "aln": "----------------------------------------------------MCGILGIVLAN---QTTPVAPELCDGCIFLQHRGQDAAGIATCGSR--GRIYQCKGNGMARDVFTQQRVSGLAG-SMGIAHLRYPTAGSSANSEAQPFYVNSPYG-INLAHNGNLVNTASLKRYMDEDVHRHINTDSDSELLLNIFAAELEKHNKYRVNNEDVFHALEGVYRLCRGGYACVGLLAGFALFGFRDPNGIRPLLFG----------ERENPDGTKDYMLASESVVFKAHNFTKYRDLKPGEAVIIPKNCSKGEPEFKQVVPINSYRPDLFEYVYFARPDSVLDGISVYHTRLAMGSKLAENILKQLKPEDIDVVIPVPDTARTCALECANVLGKPYREGFVKNRYVGRTFIMPNQRERVSSVRRKLNPMESEFKGKKVLIVDDSIVRGTTSKEIVNMAKESGATKVYFASAAPAIRYNHIYGIDLTDTKNLIAYNRTDEEVAEVIGCERVIYQSLEDLIDCCKTDKITKFEDGVFTGNYVTGVEDGYIQELEEKRESIANNSSDMKAEVDIGLYNCADY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **::* : .. :. : * : ******::***.*. . : ** *: :*.:: :. * .:**.* **.*:* . :.*** *.: :* : :****:*** *:: : :.* ****:: : :. . .. : : :. . . .*: : : ::..**. * *** :* :. .. :..::::*** * : . ::: *** * :.: : :: . :******** **:::. ** .* * . * * : *:* .**::. ..* * * : * : :********* *. * * .* :*:. :..:. **:::::*******.* *::: :::** :*:: *:*.::: **::. ::*** : : :*. :*.: : * *:*.*:.. : :. . . .. * :.. * ", "identical_positions": 127, "similar_positions": 164, "identity": "21.93%" }, { "cls_id": "homologset.agr.SGD:S000004916", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q704E8-1", "uniprot_id": "ABCB7_RAT", "id": "Q704E8-1", "name": "Iron-sulfur clusters transporter ABCB7, mitochondrial", "aln": "---------MALLAIHSWRWAAAAVAFEKHKHSAVLTRSLVSICGSGLRWSSYQSGASGSARLSQTTESLRNSTQQRWEKNNSRQLLDASKVLQA------WPLIEKRTCWHGHAGGGLHTDP---KEGLKDVDTRKIIKAMLSYVWPKDRPDLRARVAISLGFLGGAKAMNIVVPFMFKYAVDSLNQMSGNMLNLSDAPNTVATMATAVLIGYGVSRAGAAFFNEVRNAVFGKVAQNSIRRIAKNVFLHLHNLDLGFHLSRQTGALSKAIDRGTRGISFVLSALVFNLLPIVFEMTLVSSVLYYKCGAQFALVTLGTLGAYTAFTVAVTRWRTRFRIEMNKADNDAGNAAIDSLLNYETVKYFNNEKYEAQRYDGFLKTYETASLKSTSTLAMLNFGQSAIFSVGLTAIMVLASQGIVAGALTVGDLVMVNGLLFQLSLPLNFLGTVYRETRQALIDMNTLFTLLKVDTRIKDKAMASPLQITPQTATVAFDNVHFEYIEGQKVLSGVSFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRRAVGVVPQDAVLFHNTIYYNLLYGNINASPEEVYAVAKLAGLHDAILRMPHGYDTQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLDSITEETILGAMRD--VVKHRTSIFIAHRLSTVVDADEIIVLSQGKVAERGTHYGLLANSSSIYSEMWHTQSTRIQNHDNLGWDAKKESLSKEEERKKLQEEIVNSVKGCGNCSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61102-1", "uniprot_id": "ABCB7_MOUSE", "id": "Q61102-1", "name": "Iron-sulfur clusters transporter ABCB7, mitochondrial", "aln": "---------MALLAIHSWRWAAAAVAFEKHKHSAVLTRALVSMCGSGPRWSSSQRGASGSARLSQTTESLRNTTQQRWGKDNSRQLLDATKALQT------WPLIEKRTCWHGHAGGGLHTDP---KEGLKDVDTRKIIKAMLSYVWPEDRPDLRARVAISLGFLGGAKAMNIVVPFMFKYAVDSLNQMSGNMLNLSDAPNTVATMATAVLIGYGVSRAGAAFFNEVRNAVFGKVAQNSIRRIAKNVFLHLHNLDLGFHLSRQTGALSKAIDRGTRGISFVLSALVFNLLPIVFEMMLVSSVLYYKCGAQFALVTLGTLGAYTAFTVAVTRWRTRFRIEMNKADNDAGNAAIDSLLNYETVKYFNNEKYEAQRYDGFLKTYETASLKSTSTLAMLNFGQNAIFSVGLTAIMVLASQGIVAGALTVGDLVMVNGLLFQLSLPLNFLGTVYRETRQALIDMNTLFTLLKVDTRIKDKVMAPPLQITPQTATVAFDNVHFEYIEGQKVLNGVSFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNLQDVSLESLRRAVGVVPQDAVLFHNTIYYNLLYGNINASPEEVYAVAKLAGLHDAILRMPHGYDTQVGERGLKLSGGEKQRVAIARAILKNPPVILYDEATSSLDSITEETILGAMRD--VVKHRTSIFIAHRLSTVVDADEIIVLSQGKVAERGTHYGLLANSSSIYSEMWHTQSNRVQNQDSLGWDAKKESLSKEEERKKLQEEIVNSVKGCGNCSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75027-1", "uniprot_id": "ABCB7_HUMAN", "id": "O75027-1", "name": "Iron-sulfur clusters transporter ABCB7, mitochondrial", "aln": "---------MALLAMHSWRWAAAAAAFEKRRHSAILIRPLVSVSGSGPQWRPHQLGALGTARAYQIPESLKSITWQRLGKGNSGQFLDAAKALQV------WPLIEKRTCWHGHAGGGLHTDP---KEGLKDVDTRKIIKAMLSYVWPKDRPDLRARVAISLGFLGGAKAMNIVVPFMFKYAVDSLNQMSGNMLNLSDAPNTVATMATAVLIGYGVSRAGAAFFNEVRNAVFGKVAQNSIRRIAKNVFLHLHNLDLGFHLSRQTGALSKAIDRGTRGISFVLSALVFNLLPIMFEVMLVSGVLYYKCGAQFALVTLGTLGTYTAFTVAVTRWRTRFRIEMNKADNDAGNAAIDSLLNYETVKYFNNERYEAQRYDGFLKTYETASLKSTSTLAMLNFGQSAIFSVGLTAIMVLASQGIVAGTLTVGDLVMVNGLLFQLSLPLNFLGTVYRETRQALIDMNTLFTLLKVDTQIKDKVMASPLQITPQTATVAFDNVHFEYIEGQKVLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRRAVGVVPQDAVLFHNTIYYNLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLDSITEETILGAMKD--VVKHRTSIFIAHRLSTVVDADEIIVLDQGKVAERGTHHGLLANPHSIYSEMWHTQSSRVQNHDNPKWEAKKENISKEEERKKLQEEIVNSVKGCGNCSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F6F7-1", "uniprot_id": "ABCB7_DANRE", "id": "E7F6F7-1", "name": "Iron-sulfur clusters transporter ABCB7, mitochondrial", "aln": "---------MAPLLVP----LKCGFHMQRRKLSLLLQRSSAVQAWTFHDHRAANKRKERNTYLLSD-PSRESSTWANNRGQNSQQILEAVKHLH----------LQERQCWHGNAGGGLSADP---KNVLKEVNSSKILGAMFTYVWPKDRPDLRARVVISLSLLAGAKITNVMVPFMFKYAVDSLNQMSGHMLNLSDAPNTVVTMATAVLIGYGVSRTGSALFNELRNAVFGKVAQSSIRRIAKNVFLHLHNLDLGFHLSRQTGALSKAIDRGTRGISFVLSALVFNLGPTLFEMMLVSGILYYKCGGHFALVTLGTLSAYTAFTVAVTQWRTQFRIEMNKADNEAGNAAIDSLLNYETVKYFNNEKYEAERYDGFLKVYESSSLKTTSTLAMLNFGQSAIFSVGLTAIMVLASKGIMSGTMTVGDLVMVNGLLFQLSLPLNFLGTVYRETRQALIDMNTLFTLLSVDTKIKEKEMAPPLIVTPQEATIRFEDVYFEYLEGQKVLNGVSFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQQGNIYIAGQNIRDVGLESLRKAVGVVPQDAVLFHNTIFYNLMYGNINATAEDVYRVARLAGIHDAILKMPHKYDTQVGERGLKLSGGEKQRVAIARAILKNPPILLYDEATSSLDSVTEENILTSMKE--MVKDRTSVFIAHRLSTIVDADEIIVLNQGKVAERGNHQTLLDTPGSLYANLWNTQNSRILSNGSKPEPVPERVSQKEEERKKLQEEIMNSVKGCGNCSC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0C5-1", "uniprot_id": "Q9W0C5_DROME", "id": "Q9W0C5-1", "name": "Iron-sulfur clusters transporter ABCB7, mitochondrial", "aln": "MAGLLHLTKQCSIHLPAHLGRAKCYTLAKGPGTHVQARVLYSSLTKVDDKNSSDAKRKKITPFTPTPGSKLLGGVFGKKAKGGAPAAAAAKTTTLQRQRPYRPQQQQSRLCHVHIGGGSDGGSGLGKLDAPEVTSKDMLRAMMAYIWPKEDPLVRKRVGISLGLLAGSKLLTVCVPFLFKGAVDTMTTLN-----MDTAPDAVLSAATALMLGYGIARASAAGFNELRNAVFAKVAHHSIRKIASNVFLHLHNLDLAFHLNKQTGALSKTIDRGSRGINFVLSAMVFNIVPTIFELALVSSILGVKCGLAFAGVSMGCVGIYAAYTLSVTQWRTQFRVFMNQAENEAGNKAVDSLINYETVKYFNNEKYEAGCYNEVLKKYEAASLKTSSSLALLNFGQNAIFSSALSLIMVLAAKEIAQGNMTVGDLVMVNALLFQLSIPLGFLGSVYREVRQALLDMRAMFTLMNVDSSIQTAANAQPLFVDTTNSSIEFRNVSFEYEPGKPIFRDLSFTIPAGKNVAIVGGSGSGKSSMVRLLFRFFEPNSGKVLIGGQDISAVDLESLRKVIAVVPQDSVLFHNTIEHNIHYGNLSKSHAEVQNAARMADLHDSIMSWPGQYSTQVGERGLKLSGGEKQRVAIARAILKNTPILIFDEATSSLDSITEHNILQALTR--ATSGRTSICIAHRLSTVKDADEILVLENGRVGERGTHSELLRQNG-LYARLWETQTQQFD---------PSREINEEVAAKKTRGVA------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40416-1", "uniprot_id": "ATM1_YEAST", "id": "P40416-1", "name": "Iron-sulfur clusters transporter ATM1, mitochondrial", "aln": "-----------MLLLPR---CPVIGRIVRSKFRSGLIRNHSPVIFTVSKLSTQR------PLLFNSAVNLWNQAQKDITHKKSVEQFSSAPKVKT---------QVKKT------------------SKAPTLSELKILKDLFRYIWPKGNNKVRIRVLIALGLLISAKILNVQVPFFFKQTIDSMNIAW------DDPTVALPAAIGLTILCYGVARFGSVLFGELRNAVFAKVAQNAIRTVSLQTFQHLMKLDLGWHLSRQTGGLTRAMDRGTKGISQVLTAMVFHIIPISFEISVVCGILTYQFGASFAAITFSTMLLYSIFTIKTTAWRTHFRRDANKADNKAASVALDSLINFEAVKYFNNEKYLADKYNGSLMNYRDSQIKVSQSLAFLNSGQNLIFTTALTAMMYMGCTGVIGGNLTVGDLVLINQLVFQLSVPLNFLGSVYRDLKQSLIDMETLFKLRKNEVKIKN-AERPLMLPENVPYDITFENVTFGYHPDRKILKNASFTIPAGWKTAIVGSSGSGKSTILKLVFRFYDPESGRILINGRDIKEYDIDALRKVIGVVPQDTPLFNDTIWENVKFGRIDATDEEVITVVEKAQLAPLIKKLPQGFDTIVGERGLMISGGEKQRLAIARVLLKNARIMFFDEATSALDTHTEQALLRTIRDNFTSGSRTSVYIAHRLRTIADADKIIVLDNGRVREEGKHLELLAMPGSLYRELWTIQ----------------EDLDHLENELKDQQEL------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : * . . . . . : : : .:: :: *:**: :* ** *:*.:* .:* .: ***:** ::*::. . .. :: : :: **::* .:. *.*:*****.***: :** :: :.* ** :***.:**.:***.*::::***::**. **:*:**:: * **: :*..:* : * ** :::. : *: :*: .* ***:** *:*:*.*.. *:***:*:*:*******:* * *: * *. :.:* :.:**:** **. **: .*: :* :.. : * :******::* *:****:**.***:***: :*:*:**.::*.* . : *: : : * :* * * .: :: . ** :*** :.****.******::::*:***::*:.* : : *::: .:::**:.:.*****: **::** *: :*.:. : :* ... * : * * :.* ****** :*******:****.:**:. ::::*****:**: **. :* :: ***: ***** *: ***:*:**.:*:* *.*.* ** :* .:* * . .. * : ", "identical_positions": 230, "similar_positions": 216, "identity": "29.79%" }, { "cls_id": "homologset.agr.SGD:S000004920", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6A4J8-1", "uniprot_id": "UBP7_MOUSE", "id": "Q6A4J8-1", "name": "Ubiquitin C-terminal hydrolase 7", "aln": "-----------MNHQQQQQQQQKAGEQQLSE---------PEDMEMEAGDTDDPPRITQNPVING------------NVTLSDGHSNAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVR-NLPWKIMVMPRFYPDRPHQKSVGFFLQCNAES-----------DSTSWSCHAQAVLKIINYRDDDKSFSR-RISHLFFHEENDWGFSNFMAWSEVTDPEKG----FIDDDKVTFEVFV-QADAPHGVAWD------SKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKDVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPAN----------YILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGG---HDDDLSVR-----------HCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEE------------KVRYTVFKVLKNSSLAEFVQSLSQTMGFPQDQ-IRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASG--------------------------------------------------ATLPKFDK----------DHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSE--LPTAKEYFRDLYHRVDVIFCDKTIPND---------PGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQG-YRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREE-EITLYPDKHGCVRDLLEECKKAVELGDKASGRLRLLEIVSYKIIGVHQEDELLECLS---------PATSRTFRIEEIPLDQVDIDKENEML------------------------------ITVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4VSI4-1", "uniprot_id": "UBP7_RAT", "id": "Q4VSI4-1", "name": "Ubiquitin C-terminal hydrolase 7", "aln": "-----------MNHQQQQQQQQKAGEQQLSE---------PEDMEMEAGDTDDPPRITQNPVING------------NVALSDGHSNAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVR-NLPWKIMVMPRFYPDRPHQKSVGFFLQCNAES-----------DSTSWSCHAQAVLKIINYRDDDKSFSR-RISHLFFHKENDWGFSNFMAWSEVTDPEKG----FIDDDKVTFEVFV-QADAPHGVAWD------SKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPAN----------YILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGG---HDDDLSVR-----------HCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEE------------KVRYTVFKVLKNSSLAEFVQSLSQTMGFPQDQ-IRLWPMQARSNGTKRPAMLDNEADGSKTMIELSDNENPWTIFLETVDPELAASG--------------------------------------------------ATLPKFDK----------DHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSE--LPTAKEYFRDLYHRVDVIFCDKTIPND---------PGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQG-YRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREE-EITLYPDKHGCVRDLLEECKKAVELGDEASGRLRLLEIVSYKIIGVHQEDELLECLS---------PATSRTFRIEEIPLDQVNIDKENEML------------------------------ITVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q93009-1", "uniprot_id": "UBP7_HUMAN", "id": "Q93009-1", "name": "Ubiquitin C-terminal hydrolase 7", "aln": "-----------MNHQQQQQQQ-KAGEQQLSE---------PEDMEMEAGDTDDPPRITQNPVING------------NVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVR-NLPWKIMVMPRFYPDRPHQKSVGFFLQCNAES-----------DSTSWSCHAQAVLKIINYRDDEKSFSR-RISHLFFHKENDWGFSNFMAWSEVTDPEKG----FIDDDKVTFEVFV-QADAPHGVAWD------SKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPAN----------YILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGG---HDDDLSVR-----------HCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEE------------KVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQ-IRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASG--------------------------------------------------ATLPKFDK----------DHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSE--LPTAKEYFRDLYHRVDVIFCDKTIPND---------PGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQG-YRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREE-EITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLS---------PATSRTFRIEEIPLDQVDIDKENEML------------------------------VTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I3ISS5-1", "uniprot_id": "I3ISS5_DANRE", "id": "I3ISS5-1", "name": "Ubiquitin carboxyl-terminal hydrolase 7", "aln": "-----------MNHHHTQQQQQKAGEQQLSE---------PEDMEMEAGDPDDPPRIPQNPVING------------NVAMADGHNNTEEDMEDDTSWRSEATFPFVVERFSRLSESVLSPPCFVR-NLPWKIMVMPRFYPDRPHQKSVGFFLQCNAES-----------DSTSWSCHAQAMLKIINYKDDEKSFSR-RISHLFFHKENDWGFSNFMSWSDVTDPERG----FVEDDKVTFEVYV-QADAPHGVAWD------SKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRRAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKHVDYRSERIEDYYDIQLSIKGKKNIFESFKDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTFPPILHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKPDVKDPAN----------YILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEATEHNYGG---HDDDLSVR-----------HCTNAYMLVYIRESKLSEVLQPVTDMDIPQQLVERLQEEKRVEAQKRKERQEAHLYMQVQMVTEDQFCGHQGNDMYDEE------------KVKYTVFKVLKSSTLAEFVQNLSQTMGFPQDQ-MRLWPMQARSNGTKRPAMLDYEADCNKSMIDLSDNENPWTIFLETVDPEMAASG--------------------------------------------------ATLPKFDK----------DHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCERAGFQQGTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDTSE--LPTAKDYFRDLYHRVDVIFCDKTIHND---------PGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQG-YRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKAIWLNSMFREE-EITLYPDKHGCVRDLLEECKKAVELSDKGSEKLRLLEIVSYKIIGVHQEDELLECLS---------PAASRTFRIEEIPLDQVDLDKENEML------------------------------IPVAHFHKEVFGTFGIPFLLKIRQGEPFREVMKRIQSMLDIQEKEFEKFKFAIVMMGRHQYINEEDYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRGRYTYLEKAIKIHN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYQ8-1", "uniprot_id": "UBP7_DROME", "id": "Q9VYQ8-1", "name": "Ubiquitin carboxyl-terminal hydrolase 7", "aln": "MEIETDQSIEAMDTQDTQEVEILTSDLQQTQQQRNSPPQLPKFKNLIQPQLHAVGAVTQLPSENGNMPPQQLLADSSSTSFGDGEAMGIDDESKEDQFRSETTFSFTVENVVQLKSQRLSPPVYVR-MLPWRIMVIP-------NDRALGFFLQCNGEN-----------DSPTWSCNAIAELRLKCHKPDAQPFTRARIKHLFYSKENDYGYSNFITWQELKDSEKS----YVHNNSITLEVHV-VADAPHGVLWD------SKKHTGYVGLKNQGATCYMNSLLQTLYFTNSLRLSVYRIPTEADDSSKSVGLSLQRVFHELQFGDRPVGTKKLTKSFGWETLDSFMQHDVQEFLRVLLDKLESKMKGTILEGTIPGLFEGKMSSYIKCKNVDYNSTRYETFYDIQLNIKDKKNIYESFQDYVAPETLEGDNKYDAGVHGLQEASKGVIFTSFPPVLHLHLMRFQYDPVTDSSIKYNDRFEFYEHINLDRYLAESE-NTLAD----------YVLHAVLVHSGDNHGGHYVVFINPKADGRWFKFDDDVVSSCRKQEAIEQNYGG---MDDEISFHA----------KCSNAYMLVYIRQSELDRVLGDITESEISSDLVERLDLEKRIEMARRKERGEANTYVSVHVILEENFEEQHKRRLFDLE------------KVHPRVFRIKQNQTVDELVDLFVRGFGVSRQR-MRMWNLCT--AQTQKFSHFDFVAEGSRTIEQISTSQKPWVIWLQLAWTDVPGP-----------------------------------------------------LPPFNP----------KTESLLFLKYYDPRNKRLNYIGCTQQPHTRRLIDLVPDVNSKLGFEPDTELTIYDEYADKKLVNLNEPIESALFIPQDHLQGHILIFEREN-VDAKLD--LPTVGDYFLDLVYRIEIIFSDKCNPNE---------PDFTLELSNRYNYDQLANAVAERLNTDPQKLQFFMCINNYKETAGNAVPYTFKGTIKDLVSYTKQSSTKRIFYQRLSLSIHELDNKKQFKCVWVSSDLKDEKELVLYPNKNDTVKGLLEEAAKKISFAENSRRKLRLLKISNHKIVAVCKDDIPLDTLLKSNESITTAQGAQKTFRIEEVPAEDMQLA-ENEFL------------------------------IPVAHFSKELYNSFGIPFLTKARQGEPYGALKQRIQRRLNVQDKEWENYKFCVISMGHNADVNDN----TPVDLEVYRSWTSGQLPFFGLDHINKSRKRSSLNFSEKAIKIYN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50101-1", "uniprot_id": "UBP15_YEAST", "id": "P50101-1", "name": "Ubiquitin carboxyl-terminal hydrolase 15", "aln": "--------------------------------------------MSSEDELGSIGTVFPG------------------SPIDKSIGSILPQFDEEVETLLEDSFTWNIPDWNELTNPKYNSPRFRIGDFEWDILLFPQ----GNHNKGVAVYLEPHPEEKLDETTGEMVPVDPDWYCCAQFAIGISRPGNGDTINLINKSHHRFNALDTDWGFANLIDLNNLKHPSKGRPLSFLNEGTLNITAYVRILKDPTGVLWHNFLNYDSKKVTGYVGFRNQGATCYLNSLLQSYFFTKYFRKLVYEIPTEHESPNNSVPLALQRAFYQLQVSDIPLDTLELTRSFGWDTAESFTQHDVQELNRILMDRLENNMKGTPVEGKLNEIFVGKMKSYIKCINVDYESARVEDFWDLQLNVKNFKNLQESFDNYIEMELMNGENQYAAQDYGLQDAQKGVIFESFPPVLHLQLKRFEYDFNYDQMVKVNDKYEFPETIDLSPFVDKDVLKKTLDSENKDKNPYVYNLHGVLVHSGDISTGHYYTLIKPGVEDQWYRFDDERVWRVTKKQVFQENFGCDRLPDEKVRTMTRGEYQNYIIQRHTSAYMLVYIRQEQEEDLLRPVLESDVPKHVITRVREEIKERETKEKEIREAHLYVTLRLHSIKEFIHYEGFDYFAHDGFRLFAEELNDSGLQQINLKVLRTTKLSDIFASIKETMNIPQERDVKYWKMDYRRNSTLRLTQPINFESVNITLQEALKKEKKRTMQTQYGEEGVASTEEDDKALLETVSFLDLFIEEPYLELQFLNKLKEASLISKAQLDDELISTIRTNLPELTKGGIEPVFATDNKSNLLFVKSYDPHTQKLLGFGHFAVNQLQQLSDISAIIED--SISSNEKLTFYEEVQP---GTINEIYMKETIYDADIDTGDIVSFEVPGAVLPDTFPVYATIKDFYSYLRYRVKLKFSKFDGSSEEYGVSNEIPESFEFWISAYAPYDDLARMVSKYAHVKPEYLKIIALYS-----NGRFVLKSTSLLNDYLLKDFNCDQIPPFAFEVLSVPLKELERLRPIKLYWLKNSYIHYQCFEFEVANDYTESQFLEKVQHKIGFTDEEKENILLWTNTNFQFQGLLSDQNTFKDVSKHSLLFGRILPEESKLFKELNRLENVQTSSLEDFMDDENATDRPMDDEQDLGMAIEHSEDMKGRIVVVQQYFKDLENRHGISFLFNLIPDETFPKTKDRLHAKFGLGQKEFSKIKLSIGYSTEEGTVFRS--LQGFSDEELDKVILYDIMSNLDYIYMDHPDRLRSHSSYDRPMIIKN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: .. : ..: . * :* : : .*.. ..* : : * *:::* :::.:..:*: : *. .. * * * : : . : * * :.*:*::*:: .::....:. ::.:..:.: ..* . * ** *. *** *****::*******:*****: :**: :* ** :*** :...:** *:***.*::** .* *:.* :**:****:* :** ******: *:*:*.:*.:**** :**.: :* *** ***:* .***.* * * ::*:**.:*. **: *** :*: * ::*:*:* * :***:*.*** * ::**:***:* ** ** *. :* **::** * : *. :: : : : * **.******* *** . ::* :.:* :***: * *::. :.*:* *:.: : :.********:.: . :* : : ::...:: *: * : . :.** **: *: ::: .:* . : : :: ::: :. .: ::. : . :...::: :: * : * : : . . :: : .:: .: : :... ** : . . :**:* ***:.: * * :: *: . : . .: . .* :*:* ::: . : *.*: *: . .* ::: * :*:.: *.. .: .* . :* * ::*. *:: :..* *::: . *. : . . *:. : . : :: *.: : :::. : :* *:.. . : : :. :**: : : : :: .: * ..:: .: .:: :. : . .: * :::: :::: : * :: *:: . .**.** . .* : .*:: :.: :**:.: *:.: .. : . * * . :. ::::. : . ::.: * *", "identical_positions": 236, "similar_positions": 388, "identity": "18.04%" }, { "cls_id": "homologset.agr.SGD:S000004925", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LAL4-1", "uniprot_id": "A0ABK0LAL4_RAT", "id": "A0ABK0LAL4-1", "name": "Importin-5", "aln": "MCSVLPGLSLYIQVYFPCVIQFYSSEPAAERRADSDSREGRSQLHSSVSMVTSLSCEVRTVGLVPSYDRSKHRAENSLDYCGSGEKPCQGPCVSTATFLDRDLCVTSRERKFLSKEHRSESVVPCLQIPENQVEKLGATENTVRAMAAAAAEQQQFYLLLGNLLSPDNVVRKQAEETYENIPGRSK----ITFLLQAIRNTTAAEEARQMAAVLLRRLLSSAFDEVYPALPSDVQTAIKSELLMIIQMETQSSMRKKICDIAAELARNLIDEDGNN---QWPEGLKFLFDSVSSQNMGLREAALHIFWNFPGIFGNQQQHYLDVIKRMLVQCMQDQEHPSIRTLSARATAAFILAN--EHNVALFKHFADLLPGFLQAVNDSCYQNDD-SVLKSLVEIADTVPKYLRPHLEATLQLSLKLCGDTNLNNMQRQLALEVIVTLSETAAAMLRKHTN----IIAQTIPQMLAMMVDLEEDEDWANADELEDDDFDSNAVAGESALDRMACGLGGKLVLPMIKEHIMQMLQNADWKYRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTEDCPKSLLIPYLDNLVKHLHSIMVLKLQELIQKGTKLVLEQVVTSIASVADTAEEKFVPYYDLFMPSLKHIVENAVQKELRLLRGKTIECISLIGLAVGKEKFMQDASDVMQLLLKTQTDFNDMEDDDPQISYMISAWARMCKILGKEFQQYLPVVMGPLMKTASIKPEVALLDTQDMENMSDDDGWEFVNLGDQQSFGIKTAGLEEKSTACQMLVCYAKELKEGFVEYTEQVVKLMVP-LLKFYFHDGVRVAAAESMPLLLECARVRG---PEYLTQMWHFMCDALIKAIGTEPDSDVLSEIMHSFAKCIEVMGDGCLNNEHFEELGGILKAKLEEHFKNQELRQVKRQDEDYDEQVEESLQDEDDNDVYILTKVSDILHSIFSSYKEKVLPWFEQLLPLIVNLICPHRPWPDRQWGLCIFDDIIEHCSPASFKYAEYFLRPMLQYVCDNSPEVRQAAAYGLGVMAQYGGDNYRPFCTEALPLLVRVIQSADSKTKENVNATENCISAVGKIMKFKPDCVN-VEEVLPHWLSWLPLHEDKEEAVQTFSYLCDLIESNHPIVLGPN--NTNLPKIFSIIAEGEMHEAIKHEDPCAKRLANVVRQVQTSGGLWTECIAQLSPEQQAAIQ----ELLNSA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00410-1", "uniprot_id": "IPO5_HUMAN", "id": "O00410-1", "name": "Importin-5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MAAAAAEQQQFYLLLGNLLSPDNVVRKQAEETYENIPGQSK----ITFLLQAIRNTTAAEEARQMAAVLLRRLLSSAFDEVYPALPSDVQTAIKSELLMIIQMETQSSMRKKVCDIAAELARNLIDEDGNN---QWPEGLKFLFDSVSSQNVGLREAALHIFWNFPGIFGNQQQHYLDVIKRMLVQCMQDQEHPSIRTLSARATAAFILAN--EHNVALFKHFADLLPGFLQAVNDSCYQNDD-SVLKSLVEIADTVPKYLRPHLEATLQLSLKLCGDTSLNNMQRQLALEVIVTLSETAAAMLRKHTN----IVAQTIPQMLAMMVDLEEDEDWANADELEDDDFDSNAVAGESALDRMACGLGGKLVLPMIKEHIMQMLQNPDWKYRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTEDCPKSLLIPYLDNLVKHLHSIMVLKLQELIQKGTKLVLEQVVTSIASVADTAEEKFVPYYDLFMPSLKHIVENAVQKELRLLRGKTIECISLIGLAVGKEKFMQDASDVMQLLLKTQTDFNDMEDDDPQISYMISAWARMCKILGKEFQQYLPVVMGPLMKTASIKPEVALLDTQDMENMSDDDGWEFVNLGDQQSFGIKTAGLEEKSTACQMLVCYAKELKEGFVEYTEQVVKLMVP-LLKFYFHDGVRVAAAESMPLLLECARVRG---PEYLTQMWHFMCDALIKAIGTEPDSDVLSEIMHSFAKCIEVMGDGCLNNEHFEELGGILKAKLEEHFKNQELRQVKRQDEDYDEQVEESLQDEDDNDVYILTKVSDILHSIFSSYKEKVLPWFEQLLPLIVNLICPHRPWPDRQWGLCIFDDVIEHCSPASFKYAEYFLRPMLQYVCDNSPEVRQAAAYGLGVMAQYGGDNYRPFCTEALPLLVRVIQSADSKTKENVNATENCISAVGKIMKFKPDCVN-VEEVLPHWLSWLPLHEDKEEAVQTFNYLCDLIESNHPIVLGPN--NTNLPKIFSIIAEGEMHEAIKHEDPCAKRLANVVRQVQTSGGLWTECIAQLSPEQQAAIQ----ELLNSA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BKC5-1", "uniprot_id": "IPO5_MOUSE", "id": "Q8BKC5-1", "name": "Importin-5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MAAAAAEQQQFYLLLGNLLSPDNVVRKQAEETYENIPGRSK----ITFLLQAIRNTTAAEEARQMAAVLLRRLLSSAFDEVYPALPSDVQTAIKSELLMIIQMETQSSMRKKICDIAAELARNLIDEDGNN---QWPEGLKFLFDSVSSQNMGLREAALHIFWNFPGIFGNQQQHYLDVIKRMLVQCMQDQEHPSIRTLSARATAAFILAN--EHNVALFKHFADLLPGFLQAVNDSCYQNDD-SVLKSLVEIADTVPKYLRPHLEATLQLSLKLCGDTNLNNMQRQLALEVIVTLSETAAAMLRKHTS----LIAQTIPQMLAMMVDLEEDEDWANADELEDDDFDSNAVAGESALDRMACGLGGKLVLPMIKEHIMQMLQNPDWKYRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTEDCPKSLLIPYLDNLVKHLHSIMVLKLQELIQKGTKLVLEQVVTSIASVADTAEEKFVPYYDLFMPSLKHIVENAVQKELRLLRGKTIECISLIGLAVGKEKFMQDASDVMQLLLKTQTDFNDMEDDDPQISYMISAWARMCKILGKEFQQYLPVVMGPLMKTASIKPEVALLDTQDMENMSDDDGWEFVNLGDQQSFGIKTAGLEEKSTACQMLVCYAKELKEGFVEYTEQVVKLMVP-LLKFYFHDGVRVAAAESMPLLLECARVRG---PEYLTQMWHFMCDALIKAIGTEPDSDVLSEIMHSFAKCIEVMGDGCLNNEHFEELGGILKAKLEEHFKNQELRQVKRQDEDYDEQVEESLQDEDDNDVYILTKVSDILHSIFSSYKEKVLPWFEQLLPLIVNLICPQRPWPDRQWGLCIFDDIVEHCSPASFKYAEYFISPMLQYVCDNSPEVRQAAAYGLGVMAQFGGDNYRPFCTDALPLLVRVIQAPEAKTKENVNATENCISAVGKIMKFKPDCVN-VEEVLPHWLSWLPLHEDKEEAVQTFSYLCDLIESNHPIVLGPN--NTNLPKIFSIIAEGEMHEAIKHEDPCAKRLANVVRQVQTSGGLWTECIAQLSPEQQAAIQ----ELLNSA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8BIV3-1", "uniprot_id": "RNBP6_MOUSE", "id": "Q8BIV3-1", "name": "Ran-binding protein 6", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MAAAGSAGLPATVSEKQEFYQLLKNLINPSCMVRRQAEEVYENIPGLCK----TTFLLDAVRNRRAGYEVRQMAAALLRRLLSSGFEEVYPNLPPEVQRDVKIELILAVKLETHASMRKKLCDIFAVLARNLIDESGTN---HWPEGLKFLIDSIHSKNVVLWEVALHVFWHFPGIFGNQDRHDLDIIKRLLDQCIQDQEHPAIRTLSARAAATFVLAN--ENNIALFKDFADLLPGILQAVNDSCYQDDD-SVLESLVEIADTVPKYLGPYLEDTLQLSLKLCGDSRLSNLQRQLALEVIVTLSETATPMLKKHTN----IIAQAVPHILAMMVDLQDDDDWVNADEMEEDDFDSNAVAAESALDRLACGLGGKVVLPMTKEHIMQMLQSPDWKCRHAGLMALSAIGEGCHQQMEPILDETVNSVLLFLQDPHPRVRAAACTTLGQMATDFAPSFQKKFHEIVITALLRTMENQGNQRVQSHAASALVIFIEDCPKSLLILYLENMVKSLHSILVIKLQELIRNGTKLALEQLVTTIASVADAIEESFIPYYDIFMPSLKHVVELAVQKELKLLRGKTIECISHVGLAVGKEKFMQDASNVMQLLLKTQSDLNNMEDDDPQTSYMVSAWARMCKILGKDFEQYLPLVIEPLIKTASAKPDVALLDTQDVENMSDDDGWQFVNLGDQQSFGIKTSGLEAKATACQMLVYYAKELREGFVEYTEQVVKMMVP-LLKFYFHDNVRVAAAEAMPFLLECARIRG---SEYLSQMWQFICDPLIKAIGTEPDTDVLSEIMNSFAKSIEVMGDGCLNDEHLEELGGILKAKLEGHFKNQELRQVKRQEENYDQQVEMSLQDEDECDVYILTKVSDILHSLFSTYKEKILPWFEQLLPLIVNLICSSRPWPDRQWGLCIFDDIIEHCSPTSFKYVEYFRWPMLLNMRDNNPEVRQAAAYGLGVMAQFGGDDYRSLCSEAVPLLVKVIKCANSKTKKNVIATENCISAIGKILKFKPNCVN-VDEVLPHWLSWLPLHEDKEEAIQTLNFLCDLIESNHPVVIGPN--NSNLPKIISIIAEGKINETISHEDPCAKRLANVVRQIQTSEELWLECTSQLDDEQQEALH----ELLSFA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A634-1", "uniprot_id": "D4A634_RAT", "id": "D4A634-1", "name": "Ran-binding protein 6", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MAAAGSAGLPATISDKQEFYQLLKNLINPSCMVRRQAEEVYENIPGLCK----TTFLLDAVRNRRAGYEVRQMAAALLRRLLSSGFEEVYPNLPSEVQRDVKIELILAVKLETHASMRKKLCDIFAVLARNLIDENGTN---HWPEGLKFLIDSIHSKNVVLWEVALHVFWHFPGIFGNQDRHDLDIIKRLLDQCIQDQEHPAIRTLSARAAAAFVLAN--ENNIALFKDFADLLPGILQAVNDSCYQDDD-SVLESLVEIADTVPKYLGPYLEDTLQLSLKLCGDSRLSNLQRQLALEVIVTLSETATPMLKKHTN----IIAQAVPHILAMMVDLQDDDDWVNADEMEEDDFDSNAVAAESALDRLACGLGGKVVLPMTKEHIMQMLQSHDWKCRHAGLMALSAIGEGCHQQMEPILDETVNSVLLFLQDPHPRVRAAACTTLGQMATDFAPSFQKKFHEIVITALLRTMENQGNQRVQSQAASALVIFIEDCPKSLLILYLENMVKSLQSILVIKLQELIRNGTKLALEQLVTTIASVADVIEENFIPYYDIFMPSLKHVVELAVQKELKLLRGKTIECISHVGLAVGKEKFMQDASNVMQILLKTQSDLNNMEEDDPQTSYMVSAWARMCKILGKDFEQYLPLVIEPLIKTASAKPDVALLDTQDVENMSDDEGWQFVNLGDQQSFGIKTSGLEAKATACQMLVYYAKELREGFVEYTEQVVKMMVP-LLKFYFHDNVRMAAAEAMPFLLECARIRG---SEYLSQMWQFICDPLIKAIGTEPDTDVLSEIMNSFAKSIEVMGDGCLNDEHLEELGGILKAKLEGHFKNQELRQVKRQEENYDQQVEMSLQDEDECDVYILTKVSDILHSLFSTYKEKILPWFEQLLPLIVNLICSSRPWPDRQWGLCIFDDIIEHCSPTSFKYVEYFRWPMLLNMRDNNPEVRQAAAYGLGVMAQFGGDDYRSLCSEAVPLLVKVIKCANSKTKKNVIATENCISAIGKIMKFKPNCVN-VDEVLPHWLSWLPLHEDKEEAIQTLNFLCDLIESNHPVVIGPN--NSNLPKIISIIAEGKINETISLEDPCAKRLANVVRQIQTSEELWLECTSQLDDEQQEALQ----ELLSSA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60518-1", "uniprot_id": "RNBP6_HUMAN", "id": "O60518-1", "name": "Ran-binding protein 6", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MAATASAGVPATVSEKQEFYQLLKNLINPSCMVRRQAEEIYENIPGLCK----TTFLLDAVRNRRAGYEVRQMAAALLRRLLSSGFEEVYPNLPADVQRDVKIELILAVKLETHASMRKKLCDIFAVLARNLIDEDGTN---HWPEGLKFLIDSIYSKNVVLWEVALHVFWHFPGIFGTQERHDLDIIKRLLDQCIQDQEHPAIRTLSARAAAAFVLAN--ENNIALFKDFADLLPGILQAVNDSCYQDDD-SVLESLVEIADTVPKYLGPYLEDTLQLSLKLCGDSRLSNLQRQLALEVIVTLSETATPMLKKHTN----IIAQAVPHILAMMVDLQDDEDWVNADEMEEDDFDSNAVAAESALDRLACGLGGKVVLPMTKEHIMQMLQSPDWKYRHAGLMALSAIGEGCHQQMESILDETVNSVLLFLQDPHPRVRAAACTTLGQMATDFAPNFQKKFHETVIAALLRTMENQGNQRVQSHAASALIIFIEDCPKSLLVLYVDSMVKNLHSVLVIKLQELIRNGTKLALEQLVTTIASVADTIEEKFVPYYDIFMPSLKHIVELAVQKELKLLRGKTIECISHIGLAVGKEKFMQDASNVMQLLLKTQSDLNNMEDDDPQTSYMVSAWARMCKILGKDFQQYLPLVIEPLIKTASAKPDVALLDTQDVENMSDDDGWQFVNLGDQQSFGIKTSGLEAKATACQMLVYYAKELREGFVEYTEQVVKLMVP-LLKFYFHDNVRVAAAESMPFLLECARIRG---PEYLAQMWQFICDPLIKAIGTEPDTDVLSEIMNSFAKSIEVMGDGCLNDEHLEELGGILKAKLEGHFKNQELRQVKRQEENYDQQVEMSLQDEDECDVYILTKVSDILHSLFSTYKEKILPWFEQLLPLIVNLICSSRPWPDRQWGLCIFDDIIEHCSPTSFKYVEYFRWPMLLNMRDNNPEVRQAAAYGLGVMAQFGGDDYRSLCSEAVPLLVKVIKCANSKTKKNVIATENCISAIGKILKFKPNCVN-VDEVLPHWLSWLPLHEDKEEAIQTLSFLCDLIESNHPVVIGPN--NSNLPKIISIIAEGKINETINYEDPCAKRLANVVRQVQTSEDLWLECVSQLDDEQQEALQ----ELLNFA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VN44-1", "uniprot_id": "Q9VN44_DROME", "id": "Q9VN44-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MAADQAHFQQLLASLLSTDNDVRQQAEEAYNNLSRELK----VTHLLGNIQNGQQSEEARQMAAVLLRRLFTTEFFDFYKGLPAESQNQLLQQILLAVQQEVTPQLRRKICEVVAEVARNLIDEDCNN---QWPDILQFLFQCANSPTPQLQESALRIFSSVPSIFGNQEAQYIDLIKQMLAKSMDAGSDPEVRVQAVRAVGAFILYHDKENETAIHKHFADMLPRMIHITGETIEAQDDQSLLKLLIEMTENCPKFLRPQLEFIFEVCMKVFSSQDFEDSWRHLVLEVMVSLAENAPSMIRKRADK---YIVALIPLILHMMTDLDDDENWSTADVVDDDDHSDNNVIAESSLDRLACGLGGKIVLPLVMNALPVMLGHADWKHRFAALMAISAIGEGCHKQMEAILDEVMSGVLNFLSDPHPRVRYAACNAIGQMSTDFAQTFEKKFHSQVIPGLLSLLDDVENPRVQAHAGAALVNFSEDCPKNILTRYLDGIMAKLETILNSKFKELVEKGNKLVLEQVVTTIASVADTCESEFVAYYDRLMPCLKFIIQNANSDDLRMLRGKTIECVSLIGLAVGREKFIGDAGEVMDMLLVNHTEGGELADDDPQTSYLITAWARMCKILGKQFEQYLPLVMGPVMRTATMKPEVAMLDNDEVEDIDGDVDWSFINLGEQQNFAIRTAGMDDKASACEMLVCYARELKEGFAEYAEDVVRQMLP-MLKFYFHDGVRTAAAESLPYLLDCAKIKG---PQYLEGMWMFICPELLKVIVTEPEPDVQSELLNSLAKCIETLGPNCLNEDAMKQVLEIINKYVLEHFERADKRLAARNEEDYDDGVEEELAEQDDTDVYILSKIVDITHALFQTNKAQFLPAFEQVAPHFVKLLEPSRPVADRQWGLCVFDDLIEFCGPACAPYQQIFTPALVQYVCDKAPEVRQAAAYGCGVLGQFAGEQFAHTCAQIIPLLVQVINDPKAREIENISPTENAISAFAKILKYNNSALSNVDELIGVWFSWLPVSEDSEEAAHIYGYLCDLIEGNHPVILGAN--NGNLPRIVSIIAESFCTKVVEAQSATGTRMLTIVKQVESNPEVMAACASTLSPEQQQALQDAYRELANVAPA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32337-1", "uniprot_id": "IMB3_YEAST", "id": "P32337-1", "name": "Importin subunit beta-3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MSALPEEVNRTLLQIVQAFASPDNQIRSVAEKALSEEWITENNIEYLLTFLAEQAAFSQDTTVAALSAVLFRKLALKAPPSSKLMIMSKNITHIRKEVLAQIRSSLLKGFLSERADSIRHKLSDAIAECVQDDLPAWPELLQALIESLKSGNPNFRESSFRILTTVPYLITAVD---INSILPIFQSGFTDASDNVKIAAVTAFVGYFKQLP--KSEWSKLGILLPSLLNSLPRFLDDGKDDALASVFESLIELVELAPKLFKDMFDQIIQFTDMVIKNKDLEPPARTTALELLTVFSENAPQMCKSNQNYGQTLVMVTLIMMTEVSIDDDDAAEWIESDDTDDEEE-VTYDHARQALDRVALKLGGEYLAAPLFQYLQQMITSTEWRERFAAMMALSSAAEGCADVLIGEIPKILDMVIPLINDPHPRVQYGCCNVLGQISTDFSPFIQRTAHDRILPALISKLTSECTSRVQTHAAAALVNFSEFASKDILEPYLDSLLT--------NLLVLLQSNKLYVQEQALTTIAFIAEAAKNKFIKYYDTLMPLLLNVLKVN-NKDNSVLKGKCMECATLIGFAVGKEKFHEHSQELISILVALQN--SDIDEDDALRSYLEQSWSRICRILGDDFVPLLPIVIPPLLITAKATQDVGLIEEEEAANFQQYPDWDVVQVQG-KHIAIHTSVLDDKVSAMELLQSYATLLRGQFAVYVKEVMEEIALPSLDFYLHDGVRAAGATLIPILLSCLLAATGTQNEELVLLWHKASSKLIGGLMSEPMPEITQVYHNSLVNGIKVMGDNCLSEDQLAAFTKGVSANLTDTYERMQDRHG--DGDEYNENIDE---EEDFTDEDLLDEINKSIAAVLKTTNGHYLKNLENIWPMINTFLLDNEPIL-VIFALVVIGDLIQYGGEQTASMKNAFIPKVTECLISPDARIRQAASYIIGVCAQYAPSTYADVCIPTLDTLVQIVDFPGSKLEENRSSTENASAAIAKILYAYNSNIPNVDTYTANWFKTLPTITDKEAASFNYQFLSQLIENNSPIVCAQSNISAVVDSVIQALNERSLTEREGQTVISSVKKLLGFLPSSDAMAIFNRYPADIMEKVHKWFA------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: : ... :* **: .: : :* . ::*.*:*:* . . : .. : ::: :: . : : .: : * * : **: *: *::. * . : * ::::: .* :: : :: * :: . : .. . . .. * : : : : * : : : *::: *:*:.: ** : :: ::. : . :. * .**::. ::*.*. * :.. . : : : : * :: :* :* :::: . ...:***:* ***: : . : : *: :*: *.*.:**:*: .*** . : : : :. *: ::.******: ..*..:**::***: :::. *. ::..*: : . . ***::*.:**: * * ..*.:* *::.:: :: *:.... . ** :*:** :*:. :..*: *** :** * ::: ..: :*:** :** : :*:***:*** .: :::.:*: :. .:: :**. **: :*:*:*:***.:* **:*: *:: **. . :*.::: :: ::. .*..::: : :.*:*: :: * :* ::* ** *: *. *.::*:. : *.**:**.** *.* :* **.* : * :* . *: : :** .:: . :*:.: *:.:* .**.:: : . :. : ::. : * : ::*:: :: ::* * :* :: . :::.: : : * :*:: * : .:: .* :.* ::.*:::. . : * : : . ..:****:* ** .*:. . : * : **:::. . :: :* .***. :*..**: . : *: *:. ** *.* * :*.:***.* *:: . . . : :.. : * : . : . . : : : : : : ", "identical_positions": 201, "similar_positions": 406, "identity": "15.84%" }, { "cls_id": "homologset.agr.SGD:S000004926", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DFC8-1", "uniprot_id": "EIF3C_RAT", "id": "B5DFC8-1", "name": "Eukaryotic translation initiation factor 3 subunit C", "aln": "MSRFFTTGSDSESESSLSGEELVTKPVSGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEG---VPRFYVRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITNYKQNPEQSADEDAEKNEEDSEGSSDEDEDDDGVSGTAFLKKK---PDS-SGESRKFHKKMEDDDEDSEDSEDEE-WDTSSTSSDSDSEEEEGKQTVLASKFLKKAPTTEEDKKAAEKKREDKAKKKHDRKSKRMDEEEE-DNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQVRGKKGTDRATQIELLQLLVQIASENNLGVGVIVKIKFNIIASLYDYNPNLATYMKPEMWQMCLDCINELMDTLVAHSNIFVGENILE-----ESENLHNFDQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEE-----ICQIYLRRILHTYYKFD-----YKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQ-VPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMIS---KQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQG---------------------TYGGYF----RDQKDGYRKNEGYMR---RGGYRQQQ----------SQTAY--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1B4-1", "uniprot_id": "EIF3C_MOUSE", "id": "Q8R1B4-1", "name": "Eukaryotic translation initiation factor 3 subunit C", "aln": "MSRFFTTGSDSESESSLSGEELVTKPVSGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEG---VPRFYIRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITNYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVGNTTFLKKK---QES-SGESRKFHKKMEDDDEDSEDSEDEE-WDTSSTSSDSDSEEEEGKQTVLASKFLKKAPTTEEDKKAAEKKREDKAKKKHDRKSKRLDEEEE-DNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQVRGKKGTDRATQIELLQLLVQIAAENNLGVGVIVKIKFNIIASLYDYNPNLATYMKPEMWQMCLDCINELMDTLVAHSNIFVGENILE-----ESENLHNFDQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEE-----ICQIYLRRILHTYYKFD-----YKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQ-VPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMIS---KQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQG---------------------TYGGYF----RDQKDGYRKNEGYMR---RGGYRQQQ----------SQTAY--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99613-1", "uniprot_id": "EIF3C_HUMAN", "id": "Q99613-1", "name": "Eukaryotic translation initiation factor 3 subunit C", "aln": "MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEG---VPRFYIRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKK---SEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEE-DNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQIAAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFVGENILE-----ESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEE-----VCRIYLLRILHTYYKFD-----YKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQ-VPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMIS---KQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQG---------------------TYGGYF----RDQKDGYRKNEGYMR---RGGYRQQQ----------SQTAY--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B5ME19-1", "uniprot_id": "EIFCL_HUMAN", "id": "B5ME19-1", "name": "Eukaryotic translation initiation factor 3 subunit C-like protein", "aln": "MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEG---VPRFYIRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKK---SEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEEDNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQIAAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFVGENILE-----ESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEE-----VCRIYLLRILHTYYKFD-----YKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQ-VPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMIS---KQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQG---------------------TYGGYF----RDQKDGYRKNEGYMR---RGGYRQQQ----------SQTAY--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PFQ2-1", "uniprot_id": "EIF3C_DANRE", "id": "Q6PFQ2-1", "name": "Eukaryotic translation initiation factor 3 subunit C", "aln": "MSRFFATGSDSESEESSSADEITPKAAGTTLRQQALLLSDDEEDTKRVVRSAKDKRFEELTNLIKTIRNAIKIRGISKCLEEFEQLCRAFVKSKTIVDKEG---VPKFYIRLLADLEDYLNQLWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFETEIASYKENPEQSADEEEEKDDIGSGSSESDDDDDDDITAKSFMKKKPQEEEKKAPEASKFLKGAADEESESDDDEDSEDWASDSVGSDSESEDNDGTAASLAVVFLKK----DVGEKASDRKKDDRRRRHKKKERIEEEAEEEGEAEEGGWEKVKGGVPLVKEKPKMFAKGTEINTGVVVKKLSEILQARGKKGTDRAAQIELLHALAGIAAENNLGEGILVKIKFNIIASLYDYNPNLAAFMKADMWKKCLDCIDELLDILFNNNNIFIGENIAE-----DSENLAISDQPFRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVDNLKDEGRVCGIIDRLLQYLETKGSTEE-----VCRVYLRRIMHTYYKFD-----YKAHRRSLG-LQGETKSEQDQEESEGDDSAIIMDRLCKFIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGMIKDAHNALLDIQSSGRAKELLGQGLLMRNMQERNAEQEKIEKRRQ-VPFHMHINLELLECVYLVSAMLLEIPYMAAHEFDARRRMIS---KQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWRTCHSFIINEKMNSKVWDLFPEAKCVREMLVRKIQEESLRTYLFTYSSVYDSISMETLSEMFELELPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTSLQNMALQLAEKLGGLVENNERVFDLKQG---------------------VYGGYFN---RDQKGGYQQKQGYQRGDQKGGYQQKQNYQRGGYRNQNQSSY--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZAX1-1", "uniprot_id": "EIF3C_DROME", "id": "A1ZAX1-1", "name": "Eukaryotic translation initiation factor 3 subunit C", "aln": "MSRFFANGSESESES--SEEEIQATNFN---KASAFQFSDDEEEVKRVVRSTKEKRYENLTSIIKTIRNHKKIKDIPNTLSSFEDLTRAYQKALPVISKEENGITPRFYIRCLAELEDFINEVWEDREGRKNLSKNNSKSLGTLRQKVRKYIKDFEDDLSRFREAPDQESEAEDEVVALESDGGDAGDDSDAGVKPTEAVPKA---------VKSAPAKAAPADDDDSDDS---IDWDSDSE-SETESSDDENQYQNMRERFLKR---TTEKEEKDDDKRKDKRKEQKTKIRKRAEDDED-----GEWETVVKGH--VVEKPKMFEKDAEIDVPLVLAKLLEIMSARGKKRTDRRLQIDLLFELRDISDQHNLGTAVSVKIHFNIISAIYDYNQKISEPMKLEHWALLLEVMQSMMKLLLANADIIMSESVAE-----EHEEYATS--PFYVRGCPLAAVERLDDEFVKLLKECDPHSNDYVSRLKDEVNVVKTIELVLQYFERSGTNNE-----RCRIYLRKIEHLYYKFD-----PEVLKKKRGELPATTSTSVD-----------VMDKLCKFIYAKDDTDRIRTRAILAHIYHHAMHDNWFQARDLVLMSHLQDNIDAADPATRILYNRMMANLGLCAFRQGNVKDAHHCLVDLMVTGKPKELLAQGLLPQRQHERSAEQEKIEKQRQ-MPFHMHINLELLECVYLVSAMLLEIPYIAAHEFDARRRMIS---KTFYQQLRSSERQSLVGPPESMREHVVAAAKAMRCGNWQACANFIVNKKMNTKVWDLFYESDRVREMLTKFIKEESLRTYLFTYSNVYTSISIPSLAQMYELPVPKVHSIISKMIINEELMASLDDPSETVGMHRSEPSRLQALAMQFVDKVTNLVDVNEKVFDMKQGNFFQRGNMGNRGDRGYNRNQNNQGGNWLGQRRDRNNRNRNQRGHHKNNQDRQQQQQQ---------QVQTIDEE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32497-1", "uniprot_id": "EIF3C_YEAST", "id": "P32497-1", "name": "Eukaryotic translation initiation factor 3 subunit C", "aln": "MSRFFSSNYEYDVASSSSEEDLLSSSEEDLLSSSSSESELDQESDDSFFNESESE----------------SEADVDSDDSDAKPYGPDWFKKSEFRKQGG-------------GSNKFLKSSNYDSSDEESDEEDGKKVVKSAKEKLLDEMQDVYNKIS----QAENSDDWLTISNEFDLISRLLVRAQQQNWGTPNIFIKV---------------------------------------VAQVEDAVNNTQQADLKNKAVARAYNTTKQRVKKVSRENEDSMAKFRNDPESFDKEPT-----ADLDISANGFTISSSQ-----GNDQAVQEDFFTRLQTIIDSRGKKTVNQQSLISTLEELLTVAEKP----YEFIMAYLTLIPSRFDASANLS-YQPIDQWKSSFNDISKLLSILDQTIDTYQVNEFADPIDFIEDEPKEDSDGVKRILGSIFSFVERLDDEFMKSLLNIDPHSSDYLIRLRDEQSIYNLILRTQLYFEATLKDEHDLERALTRPFVKRLDHIYYKSENLIKIMETAAWNIIPAQFKSKFTSKDQLDSADYVDNLIDGLS-TILSKQNNIAVQKRAILYNIYYTALNKDFQTAKDMLLTSQVQTNINQFDSSLQILFNRVVVQLGLSAFKLCLIEECHQILNDLLSSSHLREILGQQSLHRISLNSSNNASADERARQCLPYHQHINLDLIDVVFLTCSLLIEIPRMTAFYSGIKVKRIPYSPKSIRRSLEHYDKLSFQGPPETLRDYVLFAAKSMQKGNWRDSVKYLR----EIKSWALLPNMETVLNSLTERVQVESLKTYFFSFKRFYSSFSVAKLAELFDLPENKVVEVLQSVIAELEIPAKLNDEKTIFVVEKGDEITKLEEAMVKLNKEYKIAKERLNPPSNRR---------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:.. : : . * ::: .. .. . *:*. . ....::.: . .: . .. : : * . .: :.:::. * ...:. .::. * : : ::*: . :*. .:: .::. : . .: . . * :: :. :: : : : . :..: : . : : . : * .: . : .. :* *:. **** .:: *. * * :: : : :.:*.: :* . ::: : * :: :..::. * : :.. : : * : *. :: ***:*:** * : : ****.:*: .*:** : * *:* . . :. : :: :: * *** : :. . :. . ::: *. * :*: . ::. *** :**: *::. : *:*::* *::* **: *.. :**:** :.:**:.**: ::.*: * *: :.: :*:*.* * : : . : . *: ** :*:* ****:*:: *:*..::*:*** ::*. . : : *. * : :.*. :: .: ****::*::*: *:*:*: *:*: . .:: : * * *: : . * *.. :: ***:**:*::. .* *:*: .*:::::* .* .::..:* : *: *.*:: . . :.: : *: :* :.. . . . :: ", "identical_positions": 138, "similar_positions": 304, "identity": "14.1%" }, { "cls_id": "homologset.agr.SGD:S000004927", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2QC59-1", "uniprot_id": "A0A0G2QC59_RAT", "id": "A0A0G2QC59-1", "name": "28S rRNA (uridine-N(3))-methyltransferase", "aln": "---MAERPGKRPCGPG-----EHGQRVEWRKWKQQKKEEKKKWKDLKIMKKLERQRAQEKQAKRQEEEEEAAAQRSNQGRPYTLSVALPGSILDNAQSPELRTYLAGQIARACAIFCVDEIVVFDEEGQDTK-------SVEGEFRGVGKKGQACVQLARILQYLECPQYLRKAFFPKHQD--LQFAGILNPLDSPHHMRQDEE--SEFREGVVVDRPTKAGHGSLVNCGMKKEVKIDKKLDPGLRVTVRLNQQQLPE-CKTYKGTVVSSQDPR---TKAGLYWGYTVRLASCLSAVFAEAPFQDGYDLTIGTSERGSSVASTQLP------NFRHALVVFGGLQGLEAGVDADPN--LEVADPSVLFDFYVNTCPSQGSRTIRTEEAILISLAALQPGLTQGGARPT-------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UHX9-1", "uniprot_id": "SPOUT_MOUSE", "id": "Q3UHX9-1", "name": "28S rRNA (uridine-N(3))-methyltransferase", "aln": "---MAERPRKRPCGPG-----EHGQRVEWRKWKQQKKEEKKKWKDLKIMKKLERQRAQEEEAKRQEEEEEAAAQRSNQGRPYTLSVALPGSILDNAQSPELRTYLAGQIARACTIFCVDEIVVFDEEGQDTK-------SVEGEFRGVGKKGQACVQLARILQYLECPQYLRKAFFPKHQD--LQFAGILNPLDSPHHMRQDEE--SEFREGVVVDRPTKAGHGSLVNCGMKKEVKIDKKLDPGLRVTVRLNQQQLPE-CKTYKGTVVSSQDPR---TKAGLYWGYTVRLASCLSAVFAEAPFQDGYDLTIGTSERGSDVASAQLP------SFRHALVVFGGLQGLEAAVDADPN--LEVADPSVLFDFYVNTCLSQGSRTIRTEEAILISLAALQPGLTQVGSRPASPLSGPRM-----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T280-1", "uniprot_id": "SPOUT_HUMAN", "id": "Q5T280-1", "name": "28S rRNA (uridine-N(3))-methyltransferase", "aln": "---MAERGRKRPCGPG-----EHGQRIEWRKWKQQKKEEKKKWKDLKLMKKLERQRAQEEQAKRLEEEE-AAAEKEDRGRPYTLSVALPGSILDNAQSPELRTYLAGQIARACAIFCVDEIVVFDEEGQDAK-------TVEGEFTGVGKKGQACVQLARILQYLECPQYLRKAFFPKHQD--LQFAGLLNPLDSPHHMRQDEE--SEFREGIVVDRPTRPGHGSFVNCGMKKEVKIDKNLEPGLRVTVRLNQQQHPD-CKTYHGKVVSSQDPR---TKAGLYWGYTVRLASCLSAVFAEAPFQDGYDLTIGTSERGSDVASAQLP------NFRHALVVFGGLQGLEAGADADPN--LEVAEPSVLFDLYVNTCPGQGSRTIRTEEAILISLAALQPGLIQAGARHT-------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66ID3-1", "uniprot_id": "SPOUT_DANRE", "id": "Q66ID3-1", "name": "28S rRNA (uridine-N(3))-methyltransferase", "aln": "---MADEPSEKKNKPNTLSNKEGEERKNWKKWKEQKKEEKRRRKETKLIQQLEKQKLKKEEENQQQVKQ---EEKESKGRLYTVSVALPGSVMDNAQSPELRTYLAGQIARACAVFCVDEVVIFDELGEDAK-------SVEGEFKGVGKKGQSCVQLARILQYLECPQYLRKFFFPKHQD--LQFAGLLNPLDSPHHMRIDEE--AEFREGVVLDRPVKAGKGSFVNCGMRKEVQIDKQLKTGLRVTVQLNESQNKD-GRVYKGVVVAPHIPR---TEAGLYWGYSVRLASCLSAVFSECPYKEGYDLTIGTSEKGQNTDHVTLP------AFRHMLVVFGGLQGLEASVDADEN--LTISDPSVLFDLYLNTCPAQGSRTIRTEEALLISLSGLRQKIASTFPDPPTG-----------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z830-1", "uniprot_id": "SPOUT_DROME", "id": "A1Z830-1", "name": "28S rRNA (uridine-N(3))-methyltransferase", "aln": "MKTMLAAPTASSNGRP------IGPHKSWKKVNEERKALKRQRKQDKLLKELQQAKEAESQAGKAANEV----QAKDKPNPSTLSIAVPGSILENAQSNELRAYVAGQIARAACIFRVNEVIVFDDVGIATARETKRSYEADGEGSSTGTVRSSSLQLARILQYLECPQYLRKYFFPLHKD--LKYSGLLNPLDTPHHLRQQSK--FRYREGVICDKKAKEGH-SYANVGLLNDVLVDKAIEPGVRVTVKME-PQSES-CRKQRGTLVSPDEPR---RETGVYWGYQVRIAHSMSEIFTKSPYATGYDVTVGTSDRGTNVHEVPNRSY----NFNHMLIVFGGLQGLESALANDEK--LTVDDPELLFDHYVNVLPRQGSRTIRTEEALLIALAALQEKLQPQVADVEIDLTDLLPKSEDSGIAVRRDVLVSKKQKKRKQVEDTPDETVVDEPSFSKPLPKVARLTANPFADSSEELAKNTPAQDDFEVVSSTTVSGTSHSCADDDLSRFD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04867-1", "uniprot_id": "YM91_YEAST", "id": "Q04867-1", "name": "Putative methyltransferase YMR310C", "aln": "--------------------------------------MSSTRKFKKVEKPLSQTR--------------------------HYSLCIPTTLVSDCRNLSQITHKVYQVAKFASLFNVSEVVILED---------------NSQVDATKKKISTAKLILALLQYFVTPPYLRNTVFNEKFRPYLTAASKLPRLSTLPFTRYQKQDHGRYREGLTIKMQKPTLARKKIGKVFKQTKYINIGKSKALALQSQLVPINARVTIDTITRKIVSPQEAYGDFTGLDSQYGYYTRIASSFTDLFMKGPLKEGYTQSVYVPLTTRDTSIPELSSLPTAETNPHILLVFSTWDTLARAFKLDQDQFVDCQGPQEFFDAQLP-CPVSNS---DVADAIPMTLTTLSTVF---------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * *: : *.: : *:.:* :::.:.:. . :: . *:*: . :* *.*:::::: :.: .. . .:. : :***: * ***: .* : * :. * *.: . * :.: .:***: . . . : : :: . .: : :: : :*:.. . . :** .*:* .:: :* : * ** :: .. .. * *:**. : * . * . : *. :** : ..* . :*: ::*: * : ", "identical_positions": 47, "similar_positions": 110, "identity": "9.2%" }, { "cls_id": "homologset.agr.SGD:S000004928", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DCL8-1", "uniprot_id": "IPP2_MOUSE", "id": "Q9DCL8-1", "name": "Protein phosphatase inhibitor 2", "aln": "----------MAASTASHRPIKGILKNKTSAASPPVVPSAEQPRPIVEEELSKKSQKWDEMNILATYHPAD------KDYGLMKIDEPNTPYHNMIGDDEDAYSDSEGNEVMTPDILAKKLAAAEGSEPKYRTREQESSGEEDNDLSPEEREKKRQFEMKR-----KLHYNEGLNIKLARQLISKDLHDDDEDEEMAETADGDSMNVEESSQGSTTSDHLQHKSQSS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50411-1", "uniprot_id": "IPP2_RAT", "id": "P50411-1", "name": "Protein phosphatase inhibitor 2", "aln": "----------MAASTASHRPIKGILKNKTSTTSS-VVASAEQPRRTVEEELSKKSQKWDEMNILATYHPAD------KDYGLMKIDEPDTPYHNMIGDDEDVCSDSEGNEVMTPEILAKKLAAAEGSEPKFRTREQESSGEEDNDLSPEEREKKRQFEMKR-----KLHYNEGLNIKLARQLISKDLHDDDEDEEMSETADADSMNIEESNQGSTAGDHLQHKSQSS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41236-1", "uniprot_id": "IPP2_HUMAN", "id": "P41236-1", "name": "Protein phosphatase inhibitor 2", "aln": "----------MAASTASHRPIKGILKNKTSTTSS-MVASAEQPRGNVDEELSKKSQKWDEMNILATYHPAD------KDYGLMKIDEPSTPYHSMMGDDEDACSDTEATEAMAPDILARKLAAAEGLEPKYRIQEQESSGEEDSDLSPEEREKKRQFEMKR-----KLHYNEGLNIKLARQLISKDLHDDDEDEEMLETADGESMNTEESNQGSTPSDQQQNKLRSS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96PQ5-1", "uniprot_id": "IPP2L_HUMAN", "id": "Q96PQ5-1", "name": "Putative protein phosphatase inhibitor 2-like protein 1", "aln": "----------MAASTASQRPLKGILKDNTSTTSS-MVASAEHPRGSVHEQLSKKSQKWDEMNILATYRPAD------KDYGLMKIDEPSTPYHSTMGDDEDACSDTETTEAMATDSLAKNLAAAEGLEPKYQVQEQESSGEEDSDLSPEEREKKRQFEMRR-----TLHYNEGLNIKLARQLISKDLHDDDKVEEMLETAHGESMNTEESNQGSTASDQQQNKSRSS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41818-1", "uniprot_id": "GLC8_YEAST", "id": "P41818-1", "name": "Protein GLC8", "aln": "MGGILKNPLALSPEQLAQQDPETLEEFRRQVYENTQKNAKLTSHKRNIPGLDNTKEEGEIIGTSSTFLPKDTLSLKHEQDMLAKMTPEERVQWNQRNLAENEITKKQFQDIHIDEPKTPYQGAVDPHGEYYRVDDDEDEDNSDKKPCQVANDDIDDLSLGEPEFEIKENKQPDFETNDENDEDSPEARHKKFEEMRKKHYDVRAIFNKKSREALKDEDEDEDDSTTKEP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.. ::: : : : . .. . : .: *.:..:: : :. :*: * * :: * *: . . . *: :..: : : : .*.: :: ::*...:.*.. . .:. ::.: . . : : .:: : .: * : :... * : . :: ::* :. . *. :.. :. ", "identical_positions": 14, "similar_positions": 94, "identity": "6.11%" }, { "cls_id": "homologset.agr.SGD:S000004931", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18420-1", "uniprot_id": "PSA1_RAT", "id": "P18420-1", "name": "Proteasome subunit alpha type-1", "aln": "MFRNQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQKKILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVGLLIAGYDDMGPHVFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMQCN--LDELVKHGLRALRETLPAEQD---LTTKNVSIGIVGKDLEFTIYDDDDVSPFLDGLE-------------------------ERPQRKAQPSQAADEPAEKADEPMEH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R1P4-1", "uniprot_id": "PSA1_MOUSE", "id": "Q9R1P4-1", "name": "Proteasome subunit alpha type-1", "aln": "MFRNQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQKKILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECN--LDELVKHGLRALRETLPAEQD---LTTKNVSIGIVGKDLEFTIYDDDDVSPFLDGLE-------------------------ERPQRKAQPSQAAEEPAEKADEPMEH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25786-1", "uniprot_id": "PSA1_HUMAN", "id": "P25786-1", "name": "Proteasome subunit alpha type-1", "aln": "MFRNQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQKKILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECN--LNELVKHGLRALRETLPAEQD---LTTKNVSIGIVGKDLEFTIYDDDDVSPFLEGLE-------------------------ERPQRKAQPAQPADEPAEKADEPMEH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40302-1", "uniprot_id": "PSA6_YEAST", "id": "P40302-1", "name": "Proteasome subunit alpha type-6", "aln": "MFRNNYDGDTVTFSPTGRLFQVEYALEAIKQGSVTVGLRSNTHAVLVALKRNADELSSYQKKIIKCDEHMGLSLAGLAPDARVLSNYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNTQSYGGRPYGVGLLIIGYDKSGAHLLEFQPSGNVTELYGTAIGARSQGAKTYLERTLDTFIKIDGNPDELIKAGVEAISQSLRDES----LTVDNLSIAIVGKDTPFTIYDGEAVAKYI---------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VK14-1", "uniprot_id": "Q9VK14_DROME", "id": "Q9VK14-1", "name": "Proteasome subunit alpha type", "aln": "MFRNQYDNDTTTWSPQGRLFQVEYAMEAVKQGAATVGLKGTDYAVLAALCRTSKDTNTLQRKIMPVDDHVGMSIAGLTADARVVCQYMRTECMAYRHSYNAEFPVRRLVSNLGNKLQTTTQRYDRRPYGVGLLVAGYDEQGPHIYQVMPTANVLNCKAMAIGSRSQSARTYLERNMESFEDCD--MDELICHAIQAIRGSLGSD----DVENLTINVAIVGKDVPFKMFTEAENQKYVKLVKAMDPPLEADHDPLSEEGMSDDDMTDHGPSSSGVPPNDTSDMETTASTGGSDAH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12881-1", "uniprot_id": "PSA1_DROME", "id": "P12881-1", "name": "Proteasome subunit alpha type-1", "aln": "MFRNQYDSDVTVWSPQGRLHQVEYAMEAVKLGTATVGLKNKDYAVLVALCKPTSELSDTQRKIIPIDDHLGISIAGLTADARVLSRYLRSECLNYKHSYDTTYPVSRLITNLGNKMQTTTQRYDRRPYGVGLLVAGYDERGPHIYQVTPSATFFNCKANSIGSRSQSARTYLEKNLNKFLDSS--KDEIIRHGIRAILGTLPTDEQGKDAGQYDITVAIVGKDQPFTILSNKDSAKHVAIAK------ENDNDTPRND---DD---DDRPSPPEEPAAGPRDPEVLVATEQRP--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:**.*...:** **:.*:***:**:* *:.****:.. :***.** : .: *:**: *:*:*:*:***:.***::..::* :* :: .* * : .* * ** *. ********: ***. *.*: : *:.. : . :**:***.*:****: :. * . . :*:: .:.*: :* : :.:.***** *.: .: ", "identical_positions": 84, "similar_positions": 78, "identity": "28.47%" }, { "cls_id": "homologset.agr.SGD:S000004932", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A903-1", "uniprot_id": "D4A903_RAT", "id": "D4A903-1", "name": "Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase", "aln": "-MALRWGIVSAGLIASDFTTVLSSLPPSEHQVVAVAARDLNRAEEFAQKYNIP--KAYGSYEELP---NVEVAYIATQHPQHKPAVLLCLAAGKAVLCEKPMGVNTAEVREMVAKARSQGIFLMEAIWSRFFPAMEALQEVLVQG----TIGDLRVARAEFGRDLSSVPRATDWNQAGGGLLDLGIYCVQFFSMVFGAQKPEKISAVGRIHETGVDDTVSVLLQYPG-GLHGSFTCSISSDLPNT---AYVNGTKGMAQIDK--LWCPTELVVNG----ESKEFPPPVLGKEYNFLNGSCMLYEANHIRECLRKGLKESPVVPLAESELLAEILEEVRKAIGVTFPQDKC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBB8-1", "uniprot_id": "DHDH_MOUSE", "id": "Q9DBB8-1", "name": "Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase", "aln": "-MALRWGIVSAGLIANDFTTVLSSLPSSEHQVVAVAARDLNRAEEFAQKFNIP--KAYGSYEELAKDPNVEVAYIATQHPQHKPAVLLCLAAGKAVLCEKPMGVNAAEVREMVAKARSQGVFLMEAIWSRFFPAMEALREVLVQG----TIGDLRVARAEFGFDLSHIPRATDWNQAGGGLLDLGIYCVQFLSMIFGAQKPEKISAVGRIHETGVDDTVSVLLQYPG-GVHGSFTCSISSNLPNT---AYVSGTKGMAQIQK--LWAPTELVVNG----ERKEFPPPVLGKDYNFVNGSCMLYEANHVRECLRKGLKESPVVPLAESELLAEILEEARKAIGVTFPQDKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQ10-1", "uniprot_id": "DHDH_HUMAN", "id": "Q9UQ10-1", "name": "Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase", "aln": "-MALRWGIVSVGLISSDFTAVLQTLPRSEHQVVAVAARDLSRAKEFAQKHDIP--KAYGSYEELAKDPSVEVAYIGTQHPQHKAAVMLCLAAGKAVLCEKPTGVNAAEVREMVAEARSRALFLMEAIWTRFFPASEALRSVLAQG----TLGDLRVARAEFGKNLIHVPRAVDRAQAGGALLDIGIYCVQFTSMVFGGQKPEKISVVGRRHETGVDDTVTVLLQYPG-EVHGSFTCSITVQLSNT---ASVSGTKGMVQLLNP-CWCPTELVVKG----EHKEFPLPPVPKDCNFDNGAGMSYEAKHVWECLRKGMKESPVIPLSESELLADILEEVRKAIGVTFPQDKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04869-1", "uniprot_id": "YM94_YEAST", "id": "Q04869-1", "name": "Uncharacterized protein YMR315W", "aln": "MSPLNVGIVGTGIFARDRHLPSYQEFPDKFKVIAAFNRHKAKALDFAKVADIPENKVYDNLDEILNDPHVDYIDALLPAQFNADIVEKAVKAGKPVILEKPIAANLDQAKEIVKIAESTPLPVGVAENWLYLPCIKIAKEQIEKIGPVVAFTHNSTGPFVTQNKYLTTTWRQKPEHIGGFLSDGGVHQLALVISLLGEFGSVSALTRQVRERSGADDIVFATVQLKNKEVIGSFTYGSAFGATEKSVFLKVYGKNGTVTVDLSDKKDPVVKVKLGGSAEDNGDEQIFKVDNDESFGVNAEFLNFHEAVSKKDKSLYLGTPRTAFHHLACVDAFLKSSAKNGDYVKIEQP-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*. ***..*::: * .:.:*:*. *. :* :**: :** *.*.. :*: *: : * .: ***.*: *** ..* :.:*:* *.* : : * ::*. : :. : : :: . .. . . . : ** * * *:: : : ::* . . . ..:*.** * . :* . : **** . : .:. * *.:* . : *. * * : : : :: .* .: : : : : :. :* .: . : :*:. * . . :: ", "identical_positions": 58, "similar_positions": 108, "identity": "16.57%" }, { "cls_id": "homologset.agr.SGD:S000004940", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VJ32-1", "uniprot_id": "Q9VJ32_DROME", "id": "Q9VJ32-1", "name": "Hcy-binding domain-containing protein", "aln": "MGLTR--------VLVKDGGFGTQMTVHVGDSVDGDPLWSARFNATNPAAIISTHLDFLQNGADIILTNTYQSSVDGYMEYLELDEEQSIELIKNTVRLAHIAKERYLTECYQAQLSVQEGYPLIIASIGPFGAHLHDGSEYTGSYADFVPAKEITDWHRVRIEACLEAGVDALAIETIPCQMEAEALVEMLCDDYPDVKFWVAFQCKDENTLAHGETFADAANAIWDLLAERNAQDKCLAIGVNCVHPKFVTPLFKSLNGDREVGEQIPLVVYPNSGEVYDVVNG-WQGR-EHCVPLANYVPEWAQLGAKVIGGCCRTYARDIRHIGEAIRDWNKLKKLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJ31-1", "uniprot_id": "BHMT_DROME", "id": "Q9VJ31-1", "name": "Betaine-homocysteine S-methyltransferase", "aln": "MEVNQKWNWDTKPILVKCGGFSSQLAKNVTEKVDGDPLWGSRFDATNPEAVIQTHLDFLRNGADIILTNTYQSSVEGFVKYLGVTRERGVELIQKSVQLAKQAKEQYLSEIGS---EAESALPLIMGSIGPYGAYLHDGSEYTGNYADKMSKEELRAWHKTRIEICLAAGVDGLALETLPCLMEAEAVTELVLDNFPDAKFWVSLQCMDEKHMASGENFAEAALSLWRLVQSRKAENRLLGIGLNCVNPLFVTPLLSSLT-KVAGSDRIPLVVYSNRGEIYDVEQGDWTG---TGEEVVKFVPEWIQLGVRIVGGCCRVYPTDVLAIRKYVDGLN-IKP--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04898-1", "uniprot_id": "YM99_YEAST", "id": "Q04898-1", "name": "Putative uncharacterized protein YMR321C", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMDLG----------------DKINPNLSFLGINCVSFNQSPDILESLHQALPN---MALLAYPNSGEVYDTEKKIWLPNSDKLNSWDTVVKQYISSGARIIGGCCRTSPKDIQEISAAVKKYT------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : : . :*:*** . ::.** :.*:.*.* **:**. : * . * :: . *.:::*****. . *: * : . ", "identical_positions": 24, "similar_positions": 31, "identity": "7.04%" }, { "cls_id": "homologset.agr.SGD:S000004942", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15429-1", "uniprot_id": "ENOB_RAT", "id": "P15429-1", "name": "Beta-enolase", "aln": "-------------------------------------------------------------------MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPD--LVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSP-DDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKAVFAGRKFRNPKAK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21550-1", "uniprot_id": "ENOB_MOUSE", "id": "P21550-1", "name": "Beta-enolase", "aln": "-------------------------------------------------------------------MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKARYLGKGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPD--LVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSP-DDPARHISGEKLGELYKNFIQNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKAVFAGRKFRNPKAK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13929-1", "uniprot_id": "ENOB_HUMAN", "id": "P13929-1", "name": "Beta-enolase", "aln": "-------------------------------------------------------------------MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGKGVLKAVENINNTLGPALLQKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPD--LILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSP-DDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKAIFAGRKFRNPKAK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17183-1", "uniprot_id": "ENOG_MOUSE", "id": "P17183-1", "name": "Gamma-enolase", "aln": "-------------------------------------------------------------------MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSRIAPALISSGISVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERDLPLYRHIAQLAGNSD--LILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKMVIGMDVAASEFYRDGKYDLDFKSP-ADPSRYITGDQLGALYQDFVRNYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09104-1", "uniprot_id": "ENOG_HUMAN", "id": "P09104-1", "name": "Gamma-enolase", "aln": "-------------------------------------------------------------------MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAGNSD--LILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSP-TDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04764-1", "uniprot_id": "ENOA_RAT", "id": "P04764-1", "name": "Alpha-enolase", "aln": "-------------------------------------------------------------------MSILKIHAREIFDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDNDKTRFMGKGVSKAVEHINKTIAPALVSKKLNVVEQEKIDQLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNPE--VILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKSAIAKAGYTDQVVIGMDVAASEFYRAGKYDLDFKSP-DDASRYITPDQLADLYKSFIKDYPVVSIEDPFDQDDWDAWQKFTATAGIQVVGDDLTVTNPKRIAKAAGEKSCNCLLLKVNQIGSVTESLQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGSKAKFAGRSFRNPLAK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5YC61-1", "uniprot_id": "A0A8I5YC61_RAT", "id": "A0A8I5YC61-1", "name": "phosphopyruvate hydratase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MLFPVGESKKLNVVEQEKIDQLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNPE--VILPVPAFNVINGGSHAGHKLAMQEFMILPVGASSFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNNLENKDALELLKSAIAKAGSTDQVVIGMDVAASEFYRAGKYDLDFKSP-DDASWYITPDQLADLYKSFIKDYPVVSIEDPFDQDDWD------------VVGDDLTVTSPKRIAKAAGEKSCNCLLLKVNQIGSVTESLQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGSKAKFAGRSFRNPLAK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06733-1", "uniprot_id": "ENOA_HUMAN", "id": "P06733-1", "name": "Alpha-enolase", "aln": "-------------------------------------------------------------------MSILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKGVSKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNSE--VILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYTDKVVIGMDVAASEFFRSGKYDLDFKSP-DDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDDWGAWQKFTASAGIQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACKLAQANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKAKFAGRNFRNPLAK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q1X2-1", "uniprot_id": "A0A2R8Q1X2_DANRE", "id": "A0A2R8Q1X2-1", "name": "phosphopyruvate hydratase", "aln": "-------------------------------------------------------------------MSILKIHAREIFDSRGNPTVEVDLYTKKGLFRAAVPSGASTGIYEALELRDNDKTRYLGKGVKRAVKYVNEFLAPALCNQNVSVLEQEKIDKLMLDMDGTDNKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPE--VILPVPAFNVINGGSHAGNKLAMQEFMILPVGASNFKEAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKNAISKAGYTDKIVIGMDVAASEFYKGGKYDLDFKSP-DDPSRYISPDKLADLYKSFVKDYPVVSIEDPFDQDDWEAWTNFTATTNIQVVGDDLTVTNPKRIAKAVSDKACNCLLLKVNQIGSVTESLQACKMAQTNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGDKARFAGKNFRKPI--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15007-1", "uniprot_id": "ENO_DROME", "id": "P15007-1", "name": "Enolase", "aln": "MSWTASVFLRTSTTSMKFLRLRWPLPRIPQNKSANVAPRFRSKSAVSQLSSGFKFVQIRKSTCDSNEMTIKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDNDKANYHGKSVLKAVGHVNDTLGPELIKANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAKAGAAKKGVPLYKHIADLAGNKE--IILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAMKMGSEVYHHLKNVIKAKFGLDATAVGDEGGFAPNIQSNKEALNLISDAIAKAGYTGKIEIGMDVAASEFYKDGQYDLDFKNEKSDKSQWLPADKLANLYQEFIKDFPIVSIEDPFDQDHWEAWSNLTGCTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGTVTESIAAHLLAKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEIGAGVKFAGKSFRKPQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42222-1", "uniprot_id": "ERR3_YEAST", "id": "P42222-1", "name": "Enolase-related protein 3", "aln": "-------------------------------------------------------------------MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . : * :* :*::*:.:***.***::**********.*.:*.*.:: :.**::**:**. : .::*** ***:***:*** .****** * *.** .* :**::*:**** ** : * ::* .* ******.**: .:.*::: ** .* :: :*:* *.* *:: *:***:**. * : :. :*. *:.:::.:*::*:***: :*.* ::.**** *. .** * .*..* ****:****::**:: * * ***.*:*********.**.****** ****:** .*********:::**** :* :**: *:. ", "identical_positions": 164, "similar_positions": 107, "identity": "32.54%" }, { "cls_id": "homologset.agr.SGD:S000004946", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIP1-1", "uniprot_id": "PELO_RAT", "id": "Q5XIP1-1", "name": "Protein pelota homolog", "aln": "MKLVRKDIEKDNAG--QVTLVPEEPEDMWHTYNLVQVGDSLRASTIRKVQTESSTGSVGSNRVRTTLTLCVEAIDFDSQACQLR---VKGTNIQENEYVKMGAYHTIELEPNRQFTLAKKQWDSVVLERIEQACDPAWSADVAAVVMQEGLAHVCLVTPSMTLTRAKVEVNIPRK-RKGNCSQHDRALERFYEQVVQAIQRHINFEVVKCILVASPGFVREQFCDYMFQQAVKTDNKVLLENRSKFLQVHASSGHKYSLKEVLCDPTVASRLSDTKAAGEVKALDDFYKMLQHEPDRAFYGLKQVERANEALAIDTLLISDELFRHQDVATRSRYVRLVDSVKENAGTVRIFSSLHVSGEQLGQLTGVAAILRFPVPELSDQEDD----------SSSEED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80X73-1", "uniprot_id": "PELO_MOUSE", "id": "Q80X73-1", "name": "Protein pelota homolog", "aln": "MKLVRKDIEKDNAG--QVTLVPEEPEDMWHTFNLVQVGDSLRASTIRKVQTESSTGSVGSNRVRTTLTLCVEAIDFDSQACQLR---VKGTNIQENEYVKMGAYHTIELEPNRQFTLAKKQWDSVVLERIEQACDPAWSADVAAVVMQEGLAHVCLVTPSMTLTRAKVEVNIPRK-RKGNCSQHDRALERFYEQVVQAIQRHINFEVVKCVLVASPGFVREQFCDYMFQQAVKTDNKVLLENRSKFLQVHASSGHKYSLKEALCDPTVASRLSDTKAAGEVKALDDFYKMLQHEPDRAFYGLKQVERANEALAIDTLLISDELFRHQDVATRSRYVRLVDSVKENAGTVRIFSSLHVSGEQLGQLTGVAAILRFPVPELSDQEDD----------SSSEED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BRX2-1", "uniprot_id": "PELO_HUMAN", "id": "Q9BRX2-1", "name": "Protein pelota homolog", "aln": "MKLVRKNIEKDNAG--QVTLVPEEPEDMWHTYNLVQVGDSLRASTIRKVQTESSTGSVGSNRVRTTLTLCVEAIDFDSQACQLR---VKGTNIQENEYVKMGAYHTIELEPNRQFTLAKKQWDSVVLERIEQACDPAWSADVAAVVMQEGLAHICLVTPSMTLTRAKVEVNIPRK-RKGNCSQHDRALERFYEQVVQAIQRHIHFDVVKCILVASPGFVREQFCDYLFQQAVKTDNKLLLENRSKFLQVHASSGHKYSLKEALCDPTVASRLSDTKAAGEVKALDDFYKMLQHEPDRAFYGLKQVEKANEAMAIDTLLISDELFRHQDVATRSRYVRLVDSVKENAGTVRIFSSLHVSGEQLSQLTGVAAILRFPVPELSDQEGD----------SSSEED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZWC4-1", "uniprot_id": "PELO_DANRE", "id": "Q7ZWC4-1", "name": "Protein pelota homolog", "aln": "MKLVHKDIEKDNAG--QVTLIPDEAEDMWHTYNLLQVGDSLRASTIRKVQTESSTGSVGSSRVRTTLTLCVETIDFDSQACQLR---VKGTNIQENQYVKMGAYHTIELELNRKFTLAKKVWDSVVLDRIEQACDPAQKADVAAVVMQEGLANLVLVTPAMTLLRAKVEVTIPRK-RKGSCTQHDKALERFYEAVMQGILRHFNFDVVKCILVASPGFVKDQFISYLFKEAVRQDCKLLLENRSKFMVVHSSSGHKYSLKEVLCDPAVTARLSDTKAAGEVKALEDFYKMLQQEPDRAFYGLAHVERASEALAIDILLISDTLFRHQDVATRGRYVRLVDNVKENGGTVRIFSSLHVSGEQLNQLSGVAAILRFPIADVSEPEEN----------SSSDED", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48612-1", "uniprot_id": "PELO_DROME", "id": "P48612-1", "name": "Protein pelota", "aln": "MKLLGKYVDKGMQG--NVTLVPEESEDMWHAYNLIAKGDSVRSTTIRKVQNETATGSSTSSRVRTTLTIAVESIDFDTQACVLR---LKGRNIEENQYVKMGAYHTLDLELNRKFELRKPEWDTIALERIEMACDPTQSADVAAVVMQEGLAHVCLITASMTLVRSKIEVSIPRK-RKGSVQQHEKGLAKFYEQVMQSILRHVNFDVVKCVLIASPGFVRDQFYDYMFQQAVKMDYKLLLDNKSKFMLVHASSGFKHSLREILQDPAVLAKMSDTKAAGEVKALEQFYMMLQCEPAKAFYGKKHVLQAAESQAIETLLISDNLFRCQDVSLRKEYVNLVESIRDAGGEVKIFSSMHISGEQLAQLTGIAALLRFPMPELEDSDDDDDEDGAAGGVADSDSD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33309-1", "uniprot_id": "DOM34_YEAST", "id": "P33309-1", "name": "Protein DOM34", "aln": "MKVISLKKDSFNKGGAVITLLPEDKEDLFTVYQIVDKDDELIFKKKFTSKLDEAGKKKSTDLVKLKIKVISEDFDMKDEYLKYKGVTVTDESGASNVDIPVGKYLSFTLDYVYPFTIIKQNFNKFMQKLLNEACNIEYKSDTAAVVLQEGIAHVCLVTSSSTILKQKIEYSMPKKKRTTDVLKFDEKTEKFYKAIYSAMKKDLNFDKLKTIILCSPGFYAKILMDKIFQYAEEEHNKKILDNKGMFFIAHCSTGYLQGINEVLKNPLYASKLQDTKYSKEIMVMDEFLLHLNKDDDKAWYGEKEVVKAAEYGAISYLLLTDKVLHSDNIAQREEYLKLMDSVESNGGKALVLSTLHSLGEELDQLTGIACILKYPLPDLDEDDGEE---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:: :. * :**:*:: **:: .:::: .*.: .. . : : : . :. *: .:.: * :*:. : : :.. . .* : :* * :: *: * : * ::.. . :: **: .:*.****:***:*:: *:*.: *: : *:* .:*:* *. . :.:. :**: : ..: :..:*: :* :::.**** . : . :*: * . . * :*:*:. *: .*.*:*. .:.* * :* :::.*** : *: .:::* *: : :*:** .* :* * **. **::* ::: :::: * .*:.*::.:.. .* . ::*::* **:* **:*:*.:*::*:.::.: : : ", "identical_positions": 89, "similar_positions": 170, "identity": "22.19%" }, { "cls_id": "homologset.agr.SGD:S000004947", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D8M4-1", "uniprot_id": "RL7L_MOUSE", "id": "Q9D8M4-1", "name": "Large ribosomal subunit protein uL30-like 1", "aln": "---------MAEEGERKKIPLVPENLLKKRKAYQALKATQAKQALLAKRE-RKGKQFRFRRLESFVHDSWRQQRDKVRVQRLEVKPR------------------------------------------------ALEVPDKHPLAFVIRMER--IEGVSLLVKSTIMKLGLKKLFSGVFVKVTPQSVRMLRTVEPYVTWGFPNLKSVRELILKRGQAKINNK------TVPLTDNTVIEEHLGRFGVICLEDLIHEIAFPGKHFQEVSSFLCPFLLSVARHATRNRVGFRKEMGSPGYRGDR--------------INQLIRQLN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A1K2-1", "uniprot_id": "D4A1K2_RAT", "id": "D4A1K2-1", "name": "", "aln": "MSSSWSTGKMAEEGERKKIPLVPENLLKKRKAYQALKATQAKQALLAKRE-RKGKEFRFRRLESFVHDSWRQQRDKVRVRRLEVKPR------------------------------------------------ALEVPDKHSLAFVIRMER--IQGVSLLVKSTIMKLGLKKLFSGVFVKVTPQSMRMLRTVEPYVTWGFPNLKSVRELILKRGQAKINNK------TVPLTDNTVIEEHLGQFGVICLEDLIHEIAFPGKHFQQISSFLCPFHLSVARHATKNRVGFLKEMGSPGYRGDR--------------INQLIRQLN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DKI1-1", "uniprot_id": "RL7L_HUMAN", "id": "Q6DKI1-1", "name": "Ribosomal protein uL30-like", "aln": "MISSCTTRKMAEQ-EQRKIPLVPENLLKKRKAYQALKATQAKQALLAKKEQKKGKGLRFKRLESFLHDSWRQKRDKVRLRRLEVKPH------------------------------------------------ALELPDKHSLAFVVRIER--IDGVSLLVQRTIARLRLKKIFSGVFVKVTPQNLKMLRIVEPYVTWGFPNLKSVRELILKRGQAKVKNK------TIPLTDNTVIEEHLGKFGVICLEDLIHEIAFPGKHFQEISWFLCPFHLSVARHATKNRVGFLKEMGTPGYRGER--------------INQLIRQLN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40693-1", "uniprot_id": "RLP7_YEAST", "id": "P40693-1", "name": "Ribosome biogenesis protein RLP7", "aln": "--MSSTQDSKAQTLNSNPEILLRKRRNADRTRIERQELAKKKREEQIKKKRSNK--NKFVRAESIVAKTLATSREKERIKRVSILEDKKAKNETQHIASGKDFILKITEKANGAEENSVDLEETEEEEDDGLIREKTTYDGKPALLFIVRVRGPLAVNIPNKAFKILSLLRLVETNTGVFVKLTKNVYPLLKVIAPYVVIGKPSLSSIRSLIQKRGRIIYKGENEAEPHEIVLNDNNIVEEQLGDHGIICVEDIIHEIATMGESFSVCNFFLQPFKLNREVSGFGSLNRLRKIKQREAESRTRQFSNAATAPVIEVDIDSLLAKLN", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VKC1-1", "uniprot_id": "Q9VKC1_DROME", "id": "Q9VKC1-1", "name": "", "aln": "---MSDKYAVPNKLPGKTVSVLKHRK---RRILQDESVVTQKRNDRIKKRTATKNHHKFRRAESFVMGYLKAERTSKRIKQTILRTN-------------------VTEQSAKAAD-----------------------DSNPKLLFVMRHAG--KKIFDKTTADIFRTLRMGSRHNAVFMENTKENQLLLRVIEPFVVYGNPSLSSIRELVFKKGFARIDGK------KTAIQSNTMVEQQLGDKGVICLEDIIHEICTVGPNFAAVNEFLCAFTLSSPSNGWQKKVSVSYKRGGEYGDRG-------------TAINELIARCL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . :: .. * : . . *: *:. . :* * **:: .* . *::: : .: * *::* . . : * : . ..**:: * : :*: : *:*. * *.*.*:*.*: *:* ..: : .*.::*::** *:**:**:****. * * . ** .* *. . . . *:.*: : ", "identical_positions": 48, "similar_positions": 72, "identity": "14.72%" }, { "cls_id": "homologset.agr.SGD:S000004948", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AAR8-1", "uniprot_id": "A0A8I6AAR8_RAT", "id": "A0A8I6AAR8-1", "name": "Mitochondrial S-adenosylmethionine carrier protein", "aln": "---------------------MDAPGFTASLVAGGVAGAAVDLILFPLDTIKTRLQSPQGFNQAGGFRGIYAGVPSAAIGSFPNAAAFFLTYEYVKS--------LLHTDSTSHFRPMKHMLAASTGEVVACLIRVPSEVVKQRAQVSASSKT---LQIFSTILSEEGIQ-GLYRGYKSTVLREIPFSLVQFPLWESLKALWSWRRGR-VVESWQSAVCGAFAGGFAAAVTTPLDVAKTRIMLAKAGSSTAVGNVLSAMHGVWRSQGLAGLFAGVFPRMAAISMGGFIFLGAYDQTRSLLLEVGRKSP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5U680-1", "uniprot_id": "SAMC_MOUSE", "id": "Q5U680-1", "name": "Mitochondrial S-adenosylmethionine carrier protein", "aln": "---------------------MDAPGFTASLVAGGVAGVSVDLILFPLDTIKTRLQSPQGFNKAGGFRGIYAGVPSAAVGSFPNAAAFFLTYEYVKS--------LLHTDSTSHFKPVKHMLAASTGEVVACLIRVPSEVVKQRAQVSASSKT---LQIFLTILSEEGIQ-GLYRGYKSTVLREIPFSLVQFPLWESLKALWAWRRGH-VVDSWQSAVCGAFAGGFAAAVTTPLDVAKTRIMLAKAGSSTAVGNVLSAMHGVWRSQGLAGLFAGVLPRMAAISMGGFIFLGAYDQARSLLLEVGRKSP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q70HW3-1", "uniprot_id": "SAMC_HUMAN", "id": "Q70HW3-1", "name": "Mitochondrial S-adenosylmethionine carrier protein", "aln": "---------------------MDRPGFVAALVAGGVAGVSVDLILFPLDTIKTRLQSPQGFSKAGGFHGIYAGVPSAAIGSFPNAAAFFITYEYVKW--------FLHADSSSYLTPMKHMLAASAGEVVACLIRVPSEVVKQRAQVSASTRT---FQIFSNILYEEGIQ-GLYRGYKSTVLREIPFSLVQFPLWESLKALWSWRQDH-VVDSWQSAVCGAFAGGFAAAVTTPLDVAKTRITLAKAGSSTADGNVLSVLHGVWRSQGLAGLFAGVFPRMAAISLGGFIFLGAYDRTHSLLLEVGRKSP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4V9P0-1", "uniprot_id": "SAMC_DANRE", "id": "Q4V9P0-1", "name": "Mitochondrial S-adenosylmethionine carrier protein", "aln": "---------------------MDRREFTASLVAGGCAGMCVDLTLFPLDTIKTRLQSQQGFYKAGGFRGIYAGVPSAAIGSFPNAAAFFVTYESTKS--------VFSGYTTTNLAPITHMLAASLGEIVACLIRVPTEVVKQRTQANPSIST---YRVLLNSLQEEGFR-GLYRGYGSTVLREIPFSLVQFPLWEYLKAVWWRRQGG-RLDSWQAAVCGALAGGVAAFVTTPLDVAKTWIMLAKAGTSTASGNIPMVLCEVWRSRGIPGLFAGSIPRVMFISMGGFIFLGAYEKVRRTLL-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBN7-2", "uniprot_id": "SAMC_DROME", "id": "Q9VBN7-2", "name": "S-adenosylmethionine mitochondrial carrier protein homolog", "aln": "MAAELGLESAAGSVAIKMQEPVNKLKFFHALVAGGVAGMVVDIALFPIDTVKTRLQSELGFWRAGGFRGIYKGLAPAAAGSAPTAALFFCTYECGKQ--------FLSSVTQTKDSPYVHMAAASAAEVLACLIRVPVEIAKQRSQTLQGNKQSG-LQILLRAYRTEGLKRGLYRGFGSTIMREIPFSLIQFPLWEYFKLQWTPLTGF-DSTPFSVALCGAVAGGISAGLTTPLDVVKTRIMLAERESLNRRRSARRILHGIYLERGFSGLFAGFVPRVLWITLGGAFFFGFYDLTTRILGATSTDH-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38921-1", "uniprot_id": "PET8_YEAST", "id": "P38921-1", "name": "Mitochondrial S-adenosylmethionine carrier protein", "aln": "---------------------MN--TFFLSLLSGAAAGTSTDLVFFPIDTIKTRLQAKGGFFANGGYKGIYRGLGSAVVASAPGASLFFISYDYMKVKSRPYISKLYSQGSEQLIDTTTHMLSSSIGEICACLVRVPAEVVKQRTQVHSTNSSWQTLQSILRNDNKEGLRKNLYRGWSTTIMREIPFTCIQFPLYEYLKKTWAKANGQSQVEPWKGAICGSIAGGIAAATTTPLDFLKTRLMLNKTTASLG-----SVIIRIYREEGPAVFFSGVGPRTMWISAGGAIFLGMYETVHSLLSKSFPTAGEMRA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * :*::*. ** .*: :**:**:*****: ** **::*** *: .*. .* * *: ** :*: * . : . ** ::* .*: ***:*** *:.***:*. : : **:: .****: :*::*****: :****:* :* * . .:. *:**:.***.:* *****. ** : * : : : :: ..* . :*:* ** *: ** :*:* *: . * ", "identical_positions": 92, "similar_positions": 72, "identity": "29.49%" }, { "cls_id": "homologset.agr.SGD:S000004949", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K402-1", "uniprot_id": "A0A0G2K402_RAT", "id": "A0A0G2K402-1", "name": "Myelin expression factor 2", "aln": "MADADKPEA--AAGDDGPQQQPAEP----RRDPHPGEPEKPP---RSSANGVKMENDESVKEEKSDLKEKSTGNKKANRFHPYSKDKNSGTGEKKGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQR----------------------TGTSFQGSHASD-------------VGSGLVNLPPSIVNNPN------IPPEVINNLQAG-RLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEDYRSHDSKTSQLPRGLGGIGMGLGPGGQPISASQLNITGVMGNLGPSG-MGMDGPGFGGVNRIGG-GVGFG---GLEAMNSMAGFGG----VGRMGELY-----RG-------------------AMTSSMERDFGRGDIGLSRGFGDSFGRLGSAMI--GGFAGRIGASN---------------------------------------------------------------------MGP-----VG---------TGISGSMSGMSTVTGGMGMGLDRMSSS------FDRMGPG----------------------------------------IGAILERSIDVDRGF------LSGPMGS-GMRDR----LGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIK-MENGKSKGCGTVRFESPESAEKACRIMNGIKISGREIDVRLDRNA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C854-4", "uniprot_id": "MYEF2_MOUSE", "id": "Q8C854-4", "name": "Myelin expression factor 2", "aln": "MADADKSEA--AAGDDGSQQQPAEP----RRDTHPGEPEKPP---RSSANGVKMENDESVKEEKSDLKEKSTGNKKANRFHPYSKDKNSGTGEKKGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQR----------------------TGTSFQGSHASD-------------VGSGLVNLPPSILNNPN------IPPEVISNLQAG-RLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEDYRSHDSKTSQLPRGLGGIGMGLGPGGQPISASQLNITGVMGNLGPSG-MGMDGPGFGGVNRIGG-GVGFG---GLEAMNSMAGFGG----VGRMGELY-----RG-------------------AMTSSMERDFGRGDIGLSRGFGDSFGRLGSAMI--GGFAGRIGASN---------------------------------------------------------------------MGP-----VG---------TGISGSMSGMSTVTGGMGMGLDRMSSS------FDRMGPG----------------------------------------IGAILERSIDVDRGF------LSGPMGS-GMRDR----LGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIK-MENGKSKGCGTVRFESAESAEKACRIMNGIKISGREIDVRLDRNA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2K5-1", "uniprot_id": "MYEF2_HUMAN", "id": "Q9P2K5-1", "name": "Myelin expression factor 2", "aln": "MADANKAEVPGATGGDSPHLQPAEPPGEPRREPHPAEAEKQQPQHSSSSNGVKMENDESAKEEKSDLKEKSTGSKKANRFHPYSKDKNSGAGEKKGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQR----------------------TGGSFPGGHVPD-------------MGSGLMNLPPSILNNPN------IPPEVISNLQAG-RLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEEYRSHDGKTPQLPRGLGGIGMGLGPGGQPISASQLNIGGVMGNLGPGG-MGMDGPGFGGMNRIGG-GIGFG---GLEAMNSMGGFGG----VGRMGELY-----RG-------------------AMTSSMERDFGRGDIGINQGFGDSFGRLGSAMI--GGFAGRIGSSN---------------------------------------------------------------------MGP-----VG---------SGISGGMGSMNSVTGGMGMGLDRMSSS------FDRMGPG----------------------------------------IGAILERSIDMDRGF------LSGPMGS-GMRER----IGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIK-MENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRLDRNA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N7L0-1", "uniprot_id": "A0A8M1N7L0_DANRE", "id": "A0A8M1N7L0-1", "name": "", "aln": "MADTEQVADLTEIKDEETGDSPADE--------CEQEPEQNQ----DDTNGDKTDT-----EDKSESKEKNSGGRKSHRYHPYK--ERSGGADKKTTHRNRVFISNIPYDKKWQAIKDLMREKVGEVTYVELFKDGEGKSRGCGVVEFKDEEFVKKAIEVMSKHDLNGRPLNIKEDPDGEHARRVLQR----------------------SGRMYGGGRGQD-------------SSG--INIPPSIANNPN------IPHEIISALQAG-RLGATIFVANLDFKVGWKKLKEVFGMAGTVRRADVKEDKDGKSRGMGTVTFEQPLEAVQAISMFNGQMLFDRQMHVKMDDKSLPPDDFRPVE-KSPQLPRGLGGIGMGLGPGGQPINANCLSGS----SMGPG---GMDG-GCSNMNRMSGMGGGFS---GIDCMAGMGGFSGRDMSMGRMGDMY-----RS-------------------GMGG-MDRDFGRNDLGMSRSFGDSFSSLG------GGFGG-MGNSG---------------------------------------------------------------------MGP-----MG---------SGLG--MG---------NMGMDRMNSG------FDRMSS------------------------------------------------SMDMSRGFG--QFGGSGYMG--GMSDR----SKG-GCQIFVRNLSYDLSWQKLKEKFSHCGQVMYAEIK-MENGKSKGCGTVRFDSPESAEKACRLMNGTKINGREVDVRLDRNA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9D0E1-1", "uniprot_id": "HNRPM_MOUSE", "id": "Q9D0E1-1", "name": "Heterogeneous nuclear ribonucleoprotein M", "aln": "MAAGVEAAAEVAATEPKMEEESGAP----------CVPSGNG------APGPKGEERPTQNEKRKEKNIKRGGN----RFEPYS----------NPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQK---------------------VMATTGGMGMGP--------------GGPGMINIPPSILNNPN------IPNEIIHALQAG-RLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGIVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPE-RPQQLPHGLGGIGMGLGPGGQPIDANHLSKGIGMGNLGPAG-MGMEGIGFG-INKIGGME-----GPFGGGMENMGRFGSG-MNMGRINEILSNALKRGEIIAKQGGGGAGGSVPGIERMGPGIDRISGAGMERMGAGLGHGMDRVGSEIERMGLVMDRMGSVERMGSSIERMGPLGLDHMASSIERMGQTMERIGSGVERMGAGMGFGLERMAAPIDRVGQTIERMGSGVERMGP-AIERMG-LSMDRMVPTGMGASLERMGPVMDRMATGLERMGANNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPALGAGIERMGLAMGGAGGASFDRAIEMERGNFGGSFAGS-FGGAGGHAPG----VARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIK-MENGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRIDRNA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1NZJ3-1", "uniprot_id": "A0A8M1NZJ3_DANRE", "id": "A0A8M1NZJ3-1", "name": "", "aln": "-----------------MSTEASPE----------KTGQGNA------VNGK------SNHESRKERPPKRGGGG---RFEPYS----------NPNKRYSVFVSNIPYDVKWQTLKDLMKEKVGEVTYVEHLMDGEGKSRGCAVVEFRTEELMKKAVEKVNKHVMNGRPLKVKEDPDGVISQREANRGHGGGGGGGGPPGMGGGMGGGMGGGMGGMGMGPGP------------GSSSMVNIPPSLMNNPN------IPNEVIHGLQAG-KIGSTIFVANLDYKVGWKKLKEVFGMAGMVVRADILEDKDGKSRGMGTVTFDMPIEAVQAVSMFNGQLLFNRVMHVKLDEKSLPKGDFAPPE-RAPALPRGLSGVGLGLGPGGQPIDATQLNRG-GMGNMGPG---GMDGMGYGGMGRMGGMDNFGGGGGGGGGMNNMDRFGP--SGMGRMNDMD-----RG------MGGGFDRDFSGRNDMG--MSRSNFGDSFDRGMGNSMGMDRMNSGMDRLSGGIDRMGGGG-GGGGMDRMGGGGG---GGGMDRMSD-LDRMGSSFDRMGS----GLDRLGPSMDRMGSGLDRMSTSVDRMGPGGFDRLGSSSMDRMS-GGMDFASP-MG--MDRMNTGLDRMGSN------FDRMGSGGMDRF------SSGLDRMG--------SSMDRMG--SGGIGG-QFDRPGDMDRGNFGSPFGGSGQGGGPGSGGA----NARKGCQIFVRNLPFDFTWKMLKDTFNSCGMVQYADIK-MENGKSKGCGVVRFDNPETAERACRTMNGYRLNGREIDVRIDRNA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHC7-1", "uniprot_id": "Q9VHC7_DROME", "id": "Q9VHC7-1", "name": "", "aln": "---------------MSMDASNSVE---------SREKERDR-------RGRGARGSRFTDADGNGNGAGSQGGGVAARDRSRE------------RRNCRVYISNIPYDYRWQDLKDLFRRIVGSIEYVQLFFDESGKARGCGIVEFKDPENVQKALEKMNRYEVNGRELVVKEDHGEQRDQYGRIVRDGGGGGGGGGGVQGGNGGNNGGGGGGGRDHMDDRDRGFSRRDDDRLSGRNNFNMMSNDYNNSSNYNLYGLSASFLESLGISGPLHNKVFVANLDYKVDNKKLKQVFKLAGKVQSVDLSLDKEGNSRGFAVIEYDHPVEAVQAISMLDRQMLFDRRMTVRLDR--------IPDKNEGIKLPEGLGGVGIGLGPNGEPLRDVAHNLPNGGQSQGQLLGNAQQGSQLGSVGSQPNSSAVSN--ATTNLLNNLTGVMFGNHAAVQPSPVAP-------------------------VQKPSLGNNTGSGGLNLNNLNPSILAAVVGNLGNQGGNLSNPLLSSSLSNLGLNLGNSGND----------------------------------------------------DNLPPSNVGLSNNYSSGGTGGGNSYSSGNNYSGGGGSSNLGYNAYSSS-------GGMGGG----------------------------------------NGGVGVDGNDYNTGNPLDVYGGGSNVGNSNVGSANAVGASRKSDTIIIKNVPITCTWQTLRDKFREIGDVKFAEIR-GND-----VGVVRFFKERDAELAIALMDGSRLDGRNIKVTYF---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38922-1", "uniprot_id": "HRB1_YEAST", "id": "P38922-1", "name": "Serine/arginine (SR)-type shuttling mRNA binding protein HRB1", "aln": "MSDQERGSE---------------------------------------------------NNNRSRSRSRSPVRRRMSDDHGYE--------------RDNHLSRRSGNYNGRRKFADTYRGSRDRGEYRGGRERSDYRERER-FNNRDNPRSRDRYDDRRRGRDVTGRYGNRRDDYPRSFRSRHNTR-----------------------DDSRRGGFGSS---------------GARGDYGPLLARELD--------STYEEKVNRN--YSNSIFVGNLTYDSTPEDLTEFFSQIGKVVRADIITSR-GHHRGMGTVEFTNSDDVDRAIRQYDGAFFMDRKIFVRQDN---------PPPSNNIKERKALDRGELRHNRKTHEVIVKNLPAS-------------VNWQALKDIFKECGNVAHADVELDGDGVSTGSGTVS----FYDIKDLHR-----------------------------AIEKYNG---YSIEGNVLDVKSKESVHNHSDGDDVDIPMDDS-------------------------------------------------------------------------------------------------------PVNEEARKFTEN--------VVGGG--------------------------------------------------------------------------------ERNRLIYCSNLPFSTAKSDLYDLFETIGKVNNAELRYDSKGAPTGIAVVEYDNVDDADVCIERLNNYNYGGCDLDISYAKRL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . . : : * : . * . : * . : . .: : :.** ::* . : . .: . : . .:**.** :. :.*.:.* * * .*: .: *: **:. : : . :. :*: : ::::* : *: * . . ..*. : . . : : : . : : : . . . . :. * *:. : . * : * * * *::: .. ..*.: . *: . ::. . .* ::.: ", "identical_positions": 33, "similar_positions": 108, "identity": "4.03%" }, { "cls_id": "homologset.agr.SGD:S000004950", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTW8-1", "uniprot_id": "D3ZTW8_RAT", "id": "D3ZTW8-1", "name": "Large ribosomal subunit protein bL27m", "aln": "---SLNSVSAFSALTALLSPTAPTALAVRSASKKTGGSSKNLGGKSRGKHYGIKKMEGHYVHAGNILGTQRQFRWHPGAHVGLGKNKCLYALEEGIVRYTKEVYVPNP--------------------------------KNSEAVNLVTSLPKGAVLYKTFVHVVPAKPEGTFKLVDML---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N92-1", "uniprot_id": "RM27_MOUSE", "id": "Q99N92-1", "name": "Large ribosomal subunit protein bL27m", "aln": "MAAAALTLRTRAAVTALLSPTAPTALAVRHASKKTGGSSKNLGGKSRGKHYGIKKMEGHYVHAGNILGTQRQFRWHPGAHVGLGRNKCLYALEEGIVRYTKDVYVPNP--------------------------------KNTEAVDLVTSLPKGAVLYKTFVHVVPAKPEGTFKLVDML---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P0M9-1", "uniprot_id": "RM27_HUMAN", "id": "Q9P0M9-1", "name": "Large ribosomal subunit protein bL27m", "aln": "MASVVLALRTRTAVTSLLSPTPATALAVRYASKKSGGSSKNLGGKSSGRRQGIKKMEGHYVHAGNIIATQRHFRWHPGAHVGVGKNKCLYALEEGIVRYTKEVYVPHP--------------------------------RNTEAVDLITRLPKGAVLYKTFVHVVPAKPEGTFKLVAML---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86BM8-1", "uniprot_id": "Q86BM8_DROME", "id": "Q86BM8-1", "name": "Large ribosomal subunit protein bL27m", "aln": "--MQKLTMQCLKADQPLMT-------TVRNASKKTGGSTRNKKGHARPKHRGWRVQDGHHVSEGTILATQLTTRFHPGLNVGFGRNGTLFAMEHGKVYVTCEAIDPN---------------------------------WDHTWIQRNYAGRQGQNIYKKFFNVVPENQHQRFRLVEEI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12687-1", "uniprot_id": "RM02_YEAST", "id": "P12687-1", "name": "Large ribosomal subunit protein bL27m", "aln": "---MWNPILLDTSSFSFQKHVSGVFLQVRNATKRAAGSRTSMK-DSAGRRLGPKKYEGQDVSTGEIIMRQRGTKFYPGENVGIGKDHSIFALEPGVVRYYLDPFHPKRKFIGVALRRDLKLPSPHFEPTVRRFGRFELTNKRAAYKEENSISRKDYLAKPNILKQLEVRESKRKELQDKLSKVLRDELKLDIKDIELATSYLIRVRASLKNGYPIEDARFNSRYYLKEEERLKARRESWTNEKLSESLSKIDECSDLLNSSTSFNNKLELHQYISEQEKQALKAKLLEDLEKSQHLETKKDKNYIKALFKDACNFLTLSEEVHLRRKYLKSVFPETDSTVETKSGKKSIVSRRFDYTKNKVEVIARSRRAFLSKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : .: . ** *:*::.** . .: :: * : :*: * * *: * :::** :**.*:: ::*:* * * : *: : :. .:.: : . .* : ", "identical_positions": 23, "similar_positions": 42, "identity": "6.13%" }, { "cls_id": "homologset.agr.SGD:S000004951", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2K5-1", "uniprot_id": "LST8_RAT", "id": "Q9Z2K5-1", "name": "Target of rapamycin complex subunit LST8", "aln": "MNTTPGTVGSDPVILATAGYDHTVRFWQAHSGICTRTVQHQD-SQVNALEITPDRSMIAATGYQHIRMYDLNSNNPNPIISYDGVSKNIASVGFHEDGRWMYTGGEDCTARIWDLRSRNLQCQRIFQVNAPINCVCLHPNQAELIVGDQSGTSHIWDLK-TDHNEQLIPEPEFSITSAHIDPDASYMAAVNSAGNCFVWNLTGGIGDEVTQLIPKTKIPAHTRYALQCRFSPDSTLLATCSADQTCKIWRTSN-FSLMTELSIKSSNPGESSRGWMWGCAFSGDSQYIVTASSDNLARLWCVETGEIKREYGGHQKAVVCLAFNDSVLG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCJ1-1", "uniprot_id": "LST8_MOUSE", "id": "Q9DCJ1-1", "name": "Target of rapamycin complex subunit LST8", "aln": "MNTTPGTVGSDPVILATAGYDHTVRFWQAHSGICTRTVQHQD-SQVNALEITPDRSMIAAAGYQHIRMYDLNSNNPNPIISYDGVSKNIASVGFHEDGRWMYTGGEDCTARIWDLRSRNLQCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWDLK-TDHNEQLIPEPESSITSAHIDPDASYMAAVNSAGNCYVWNLTGGIGDDVTQLIPKTKIPAHTRYALQCRFSPDSTLLATCSADQTCKIWRTSN-FSLMTELSIKSSNPGESSRGWMWGCAFSGDSQYIVTASSDNLARLWCVETGEIKREYGGHQKAVVCLAFNDSVLG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BVC4-1", "uniprot_id": "LST8_HUMAN", "id": "Q9BVC4-1", "name": "Target of rapamycin complex subunit LST8", "aln": "MNTSPGTVGSDPVILATAGYDHTVRFWQAHSGICTRTVQHQD-SQVNALEVTPDRSMIAAAGYQHIRMYDLNSNNPNPIISYDGVNKNIASVGFHEDGRWMYTGGEDCTARIWDLRSRNLQCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWDLK-TDHNEQLIPEPEVSITSAHIDPDASYMAAVNSTGNCYVWNLTGGIGDEVTQLIPKTKIPAHTRYALQCRFSPDSTLLATCSADQTCKIWRTSN-FSLMTELSIKSGNPGESSRGWMWGCAFSGDSQYIVTASSDNLARLWCVETGEIKREYGGHQKAVVCLAFNDSVLG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803V5-1", "uniprot_id": "LST8_DANRE", "id": "Q803V5-1", "name": "Target of rapamycin complex subunit lst8", "aln": "MNVNQGTVGSDPVILATAGYDHTVRFWQAHSGICTRTVQHQD-SQVNSLEVTPDRSMIAAAGYQHIRMYDLNSNNPNPVINYDGVSKNITSVGFHEDGRWMYTGGEDCMARIWDLRSRNLQCQRIFQVNAPINCVCLHPNQAELIVGDQSGVIHIWDLK-TDHNEQLIPEPDVSVNSVHIDPDASYMAAVNSSGNCYVWNLAGGMGDEVTQLIPKTKIPAHKRYSLRCKFSPDSTLLATCSADQTCKIWRTSN-FSLMTELSIKSNNPGETSRGWMWDCAFSGDSQYIVTASSDNLARLWCVETGEIKREYSGHQKAVVCLAFNDSVLG-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W328-1", "uniprot_id": "LST8_DROME", "id": "Q9W328-1", "name": "Protein LST8 homolog", "aln": "MGDQQ------QLILATGGYDHTIKVWQAHTGNCIKTMRFVETSQVNALDRTPDKTRLAACGYQCIRLYDLESNCTAPVINFDGVQKNVTRLGFQEDGNWMFTAGEDHHVRIWDMIAAPPHCSRIFDCEAPVNAACLHPNQVEIAMGSQNGSVFLWDVK-SERHERIVPEVDASIQDVAISPDGRYLAAANNKGNCYIWSLTS-QDQKMSTLRPNRKIPAHSRYILRCKFSPDSRLLLTTSGDGTVCIWKTDD-FSKWRELCIEN--------YWVWDAAFSADSKWLFTASSDGIARLWKLQTKSSIRDYTGHTKAITALSFKDEIVGK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41318-1", "uniprot_id": "LST8_YEAST", "id": "P41318-1", "name": "Target of rapamycin complex subunit LST8", "aln": "----------MSVILVSAGYDHTIRFWEALTGVCSRTIQHSD-SQVNRLEITNDKKLLATAGHQNVRLYDIRTTNPNPVASFEGHRGNVTSVSFQQDNRWMVTSSEDGTIKVWDVRS--PSIPRNYKHNAPVNEVVIHPNQGELISCDRDGNIRIWDLGENQCTHQLTPEDDTSLQSLSMASDGSMLAAANTKGNCYVWEMPN--HTDASHLKPVTKFRAHSTYITRILLSSDVKHLATCSADHTARVWSIDDDFKLETTLDGHQR--------WVWDCAFSADSAYLVTASSDHYVRLWDLSTREIVRQYGGHHKGAVCVALNDV----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**.:.*****::.*:* :* * :*::. : **** *: * *:. :*: *:* :*:**:.:. . *: .::* *:: :.*::*..** *..** ::**: : * :. :**:* . :**** *: .:.* :**: .: .:: ** : *: . : .*. :**.*. ***::*.:.. . : * * *: **. * : :*.* * * *.* * :* .: *. * .. *:*..***.** ::.***** .*** :.* . *:* ** *. ..::::* ", "identical_positions": 98, "similar_positions": 110, "identity": "29.7%" }, { "cls_id": "homologset.agr.SGD:S000004952", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K9H9-1", "uniprot_id": "A0A0G2K9H9_RAT", "id": "A0A0G2K9H9-1", "name": "", "aln": "MFKRTVLSCPPPAAPPLQARGAFRSFPHFWGEDFLASLMFKIQLEPLKLRAWTLNGFVKFRNKEPSTGPVAVMG----------------KDYYKILG----IPSGANED-EIKKAYR--------------------------------------------KMALKYHPD-------------------KNKEPNAEEKFKEIAEAYDVLSD-------------PKKRSLYDQY---------GEEGLK--------------TGG---GTSGGS-GGSFHYTFHG-DPHATFASFFGGSNPFDIFFASSR---STRPFSGFDPDDMDVDED--EDPFGAFGRFGFNGLS------------RGPRRAPEPLYP-RRKVQDPPVVHELRVSLEEIYHGSTKRMKITRRRLNPDGRTVRTEDKILHIVIKRGWKEGTKITFPKEGDATPDN-IPADIVFVLKDKPHAHFRRDGTNVLYSALISLKEALCGCTVNIPTIDGRVIPLPCND--VIKPGTVKRLRGEGLPFPKVPTQRGDLIVEFKVRFPDRLTPQTRQILKQHLPCS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89114-1", "uniprot_id": "DNJB5_MOUSE", "id": "O89114-1", "name": "DnaJ homolog subfamily B member 5", "aln": "------------------------------------------------------------------------MG----------------KDYYKILG----IPSGANED-EIKKAYR--------------------------------------------KMALKYHPD-------------------KNKEPNAEEKFKEIAEAYDVLSD-------------PKKRSLYDQY---------GEEGLK--------------TGG---GSSGGS-GGSFHYTFHG-DPHATFASFFGGSNPFDIFFASSR---STRPFSGFDPDDMDVDED--EDPFGAFGRFGFNGLS------------RGPRRAPEPLYP-RRKVQDPPVVHELRVSLEEIYHGSTKRMKITRRRLNPDGRTVRTEDKILHIVIKRGWKEGTKITFPKEGDATPDN-IPADIVFVLKDKPHAHFRRDGTNVLYSALISLKEALCGCTVNIPTIDGRVIPLPCND--VIKPGTVKRLRGEGLPFPKVPTQRGDLIVEFKVRFPDRLTPQTRQILKQHLPCS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75953-3", "uniprot_id": "DNJB5_HUMAN", "id": "O75953-3", "name": "DnaJ homolog subfamily B member 5", "aln": "------------------------------------------------------------------------MG----------------KDYYKILG----IPSGANED-EIKKAYR--------------------------------------------KMALKYHPD-------------------KNKEPNAEEKFKEIAEAYDVLSD-------------PKKRGLYDQY---------GEEGLK--------------TGG---GTSGGS-SGSFHYTFHG-DPHATFASFFGGSNPFDIFFASSR---STRPFSGFDPDDMDVDED--EDPFGAFGRFGFNGLS------------RGPRRAPEPLYP-RRKVQDPPVVHELRVSLEEIYHGSTKRMKITRRRLNPDGRTVRTEDKILHIVIKRGWKEGTKITFPKEGDATPDN-IPADIVFVLKDKPHAHFRRDGTNVLYSALISLKEALCGCTVNIPTIDGRVIPLPCND--VIKPGTVKRLRGEGLPFPKVPTQRGDLIVEFKVRFPDRLTPQTRQILKQHLPCS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5WUU0-1", "uniprot_id": "A5WUU0_DANRE", "id": "A5WUU0-1", "name": "", "aln": "------------------------------------------------------------------------MG----------------KDYYKILG----IPSGSNED-EIKKAYR--------------------------------------------KMALKFHPD-------------------KNKDPNAEEKFKEIAEAYEVLSD-------------PKKRVIYDQY---------GEDGLK--------------TGGT--GSSSGQ-GTTYHYTFHG-DPHATFASFFGGSNPFDIFFGSSRQRGNTNGFPDHGDHDMDIDMDGEDDPFSSFSHFGFNGVNGFHH-------GGGRRHRNEPLHGGRKKLQDPPVVHELKVSLEEIFHGCTKRMRITRRRLNPDRKTMRTEDKILNIVIKRGWKEGTKITFPKEGDETPEN-IPADIAFVLKDKGHPLFRRDGSNIIYTTKIGLKEALCGCTVNIPTIDNRAITLPCND--IIKPGTIKRLRGEGLPFPKNPSQRGDLIVEFQVRFPDRIPPQSREIIKQHLPQS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9D832-1", "uniprot_id": "DNJB4_MOUSE", "id": "Q9D832-1", "name": "DnaJ homolog subfamily B member 4", "aln": "------------------------------------------------------------------------MG----------------KDYYHILG----IDKGATDE-DVKKAYR--------------------------------------------KQALKFHPD-------------------KNKSPQAEEKFKEVAEAYEVLSD-------------PKKREIYDQF---------GEEGLK--------------GGA---GGTDGQ-GGTFRYTFHG-DPHATFAAFFGGSNPFEIFFGRRMG-------GGRDSEEMEIDGD----PFSAFG-FSMNGYP----------------RDRNSVGP-SRLKQDPPIIHELKVSLEEIYSGCTKRMKISRKRLNPDGRSYRSEDKILTIEIKKGWKEGTKITFPREGDETPNS-IPADIVFVIKDKEHPKFKRDGSNIVYTAKISLREALCGCSLNVPTMDGRNLPMSVTD--IVKPGMRRRVIGYGLPFPKNPDQRGDLLIEFDVSFPDVISAASKEILRKHLPAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XIP0-1", "uniprot_id": "Q5XIP0_RAT", "id": "Q5XIP0-1", "name": "", "aln": "------------------------------------------------------------------------MG----------------KDYYHILG----IEKGATDE-DIKKAYR--------------------------------------------KQALKFHPD-------------------KNKSPQAEEKFKEVAEAYEVLSD-------------PKKREIYDQF---------GEEGLK--------------GGA---GGTDGQ-GGTFRYTFHG-DPHATFAAFFGGANPFEIFFGRRMG-------GGRDSEEMEIDGD----PFSAFG-FSMNGYP----------------RDRNSVGP-SRLKQDPPIIHELKVSLEEIYSGCTKRMKISRKRLNPDGRSYRSEDKILTIEIKKGWKEGTKITFPREGDETPNS-IPADIVFIIKDKEHPKFKRDGSNIVYTAKISLREALCGCSINVPTMDGRNIPMSVTD--IVKPGMRRRIIGYGLPFPKNPDQRGDLLIEFDVSFPDVISAASKEILRKHLPAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UDY4-1", "uniprot_id": "DNJB4_HUMAN", "id": "Q9UDY4-1", "name": "DnaJ homolog subfamily B member 4", "aln": "------------------------------------------------------------------------MG----------------KDYYCILG----IEKGASDE-DIKKAYR--------------------------------------------KQALKFHPD-------------------KNKSPQAEEKFKEVAEAYEVLSD-------------PKKREIYDQF---------GEEGLK--------------GGA---GGTDGQ-GGTFRYTFHG-DPHATFAAFFGGSNPFEIFFGRRMG-------GGRDSEEMEIDGD----PFSAFG-FSMNGYP----------------RDRNSVGP-SRLKQDPPVIHELRVSLEEIYSGCTKRMKISRKRLNADGRSYRSEDKILTIEIKKGWKEGTKITFPREGDETPNS-IPADIVFIIKDKDHPKFKRDGSNIIYTAKISLREALCGCSINVPTLDGRNIPMSVND--IVKPGMRRRIIGYGLPFPKNPDQRGDLLIEFEVSFPDTISSSSKEVLRKHLPAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QYJ3-1", "uniprot_id": "DNJB1_MOUSE", "id": "Q9QYJ3-1", "name": "DnaJ homolog subfamily B member 1", "aln": "------------------------------------------------------------------------MG----------------KDYYQTLG----LARGASDD-EIKRAYR--------------------------------------------RQALRYHPD-------------------KNKEPGAEEKFKEIAEAYDVLSD-------------PRKREIFDRY---------GEEGLK--------------GGSPSGGSSGGANGTSFSYTFHG-DPHAMFAEFFGGRNPFDTFFGQRNG-----------EEGMDIDDT-----FSSFPMG-MGGFT------------NMNFGRSRPSQEPTRKKQDPPVTHDLRVSLEEIYSGCTKKMKISHKRLNPDGKSIRNEDKILTIEVKRGWKEGTKITFPKEGDQTSNN-IPADIVFVLKDKPHNIFKRDGSDVIYPARISLREALCGCTVNVPTLDGRTIPVVFKD--VIRPGMRRKVPGEGLPLPKTPEKRGDLVIEFEVIFPERIPVSSRTILEQVLPI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25685-1", "uniprot_id": "DNJB1_HUMAN", "id": "P25685-1", "name": "DnaJ homolog subfamily B member 1", "aln": "------------------------------------------------------------------------MG----------------KDYYQTLG----LARGASDE-EIKRAYR--------------------------------------------RQALRYHPD-------------------KNKEPGAEEKFKEIAEAYDVLSD-------------PRKREIFDRY---------GEEGLK--------------GSGPSGGSGGGANGTSFSYTFHG-DPHAMFAEFFGGRNPFDTFFGQRNG-----------EEGMDIDDP-----FSGFPMG-MGGFT------------NVNFGRSRSAQEPARKKQDPPVTHDLRVSLEEIYSGCTKKMKISHKRLNPDGKSIRNEDKILTIEVKKGWKEGTKITFPKEGDQTSNN-IPADIVFVLKDKPHNIFKRDGSDVIYPARISLREALCGCTVNVPTLDGRTIPVVFKD--VIRPGMRRKVPGEGLPLPKTPEKRGDLIIEFEVIFPERIPQTSRTVLEQVLPI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZUU5-1", "uniprot_id": "D3ZUU5_RAT", "id": "D3ZUU5-1", "name": "", "aln": "--------------------------------------------------------------MSCVTQRAAAIGRCGATHREGRKVLEGWRDLEASAGRVYRVRDGAAAEPEAATAGRRWPWARTTTRRWAWPAARPTTRSSGPTAARRCATTRTRTRSPAPRRSSRRSPRPTTCSATRASARFSTAMERKVRVRAARVTRRLTGEETEALGASLRLRRGTDGPGIPRRRCLLHLLSNRRPQTGGGALGLK--------------GGGPSGGSSGGANGTSFSYTFHG-DPHAMFAEFFGGRNPFDTFFGQRNG-----------EEGMDIDDP-----FSSFPMG-MGGFT------------NMNFGRSRPTQEPTRKKQDPPVTHDLRVSLEEIYSGCTKKMKISHKRLNPDGKSIRNEDKILTIEVKRGWKEGTKITFPKEGDQTSNN-IPADIVFVLKDKPHNIFKRDGSDVIYPARISLREALCGCTVNVPTLDGRTIPVVFKD--VIRPGMRRKVPGEGLPLPKTPEKRGDLVIEFEVIFPDRIPISSRTILEQVLPI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1PA47-1", "uniprot_id": "A0A8M1PA47_DANRE", "id": "A0A8M1PA47-1", "name": "", "aln": "---------------------------------------------------------------------MVKMG----------------KDYYSVLG----IQKGASDD-EIKKAYR--------------------------------------------KQALKYHPD-------------------KNKSAGAEEKFKEIAEAYDVLSD-------------PKKKDIYDRF---------GEEGLK--------------GGAPGGGGGGGN----YTYTFQG-DPHAMFSEFFGGRNPFEHIFGHNGGM----------DENMETDDP-----FASFGMGGIGGFP------------RSFTTHSHGGR--MERKQDPAVIHDLRVSLDEVFTGCTKKMKISRKRLNPDGRTTRSEDKILTVEVKKGWKEGTKITFPREGDETPSN-IPADVVFVLKDKPHPVYKRDGSDIIYPAKITLKEALCGCVINVPTLDGRTVKVTSQD--IVRPGMKRRLTGEGLPLPKAPDRRGDLVVEYEVRFPEKLSQNAKDTIANVLPAS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q80Y75-1", "uniprot_id": "DJB13_MOUSE", "id": "Q80Y75-1", "name": "DnaJ homolog subfamily B member 13", "aln": "------------------------------------------------------------------------MG----------------LDYYAVLQ----VTRNSEDA-QIKKAYR--------------------------------------------KLALKNHPL-------------------KSSEPGAPEIFKQIAEAYDVLSD-------------PVKRGIYDKF---------GEEGLK--------------GGIP--LEFGSQTPWTTGYVFHG-NPDKVFHEFFGGDNPFSEFFDAEGN-------------DIDLN---------------FGGLW-----------------------GRGVQKQDPPIERDLYLSLEDLFFGCTKKIKISRRVLNEDRYSSTIKDKILTIDVRPGWRQGTRITFEKEGDQGPNI-IPADIIFIVKEKLHPRFRREHDNLFFVYPIPLGKALTCCTVEVKTLDDRLLNIPIND--IVHPKYFKIVPGEGMPLPENPSKKGDLFIFFDIQFPTRLTPQKKQMLRQALLT-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P59910-1", "uniprot_id": "DJB13_HUMAN", "id": "P59910-1", "name": "DnaJ homolog subfamily B member 13", "aln": "------------------------------------------------------------------------MG----------------QDYYSVLG----ITRNSEDA-QIKQAYR--------------------------------------------RLALKHHPL-------------------KSNEPSSAEIFRQIAEAYDVLSD-------------PMKRGIYDKF---------GEEGLK--------------GGIP--LEFGSQTPWTTGYVFHG-KPEKVFHEFFGGNNPFSEFFDAEGS-------------EVDLN---------------FGGLQ-----------------------GRGVKKQDPQVERDLYLSLEDLFFGCTKKIKISRRVLNEDGYSSTIKDKILTIDVKPGWRQGTRITFEKEGDQGPNI-IPADIIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVEVRTLDDRLLNIPIND--IIHPKYFKKVPGEGMPLPEDPTKKGDLFIFFDIQFPTRLTPQKKQMLRQALLT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPY9-1", "uniprot_id": "Q9VPY9_DROME", "id": "Q9VPY9-1", "name": "J domain-containing protein", "aln": "------------------------------------------------------------------------MG----------------KDYYKILG----LPKTATDD-EIKKAYR--------------------------------------------KLALRYHPD-------------------KNKAANAEDKFKEVAEAYEVLSD-------------KSKREVYDKY---------GEDGLK----------------SGGTR-NGGPSSNSFTYQFHG-DPRATFAQFFGNSNPFASFFDMGDN-------------LFDKKVF-DLDTEPDFFSSPFGGIGSRHGLGSGFRPSFRSHSFNVHTPFKKEQKQDPPVEHDLYVTLEEIYHGCVKKMKISR-RIVQADGSSRKEEKFLAISIKPGWKSGTKVTFQKEGDQAPGK-IPADIVFIIRDKPHAMFKREGSDLRYTARLTLKQALCGVVFQVPTMSGDKLRISTMQ-EIIKPNTVKRIQGYGLPFPKDTTRKGDLLVAFDIQFPEKLTAAQKEVLKDML---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q24133-1", "uniprot_id": "DNAJ1_DROME", "id": "Q24133-1", "name": "DnaJ protein homolog 1", "aln": "------------------------------------------------------------------------MG----------------KDFYKILG----LERKASDD-EIKKAYR--------------------------------------------KLALKYHPD-------------------KNKSPQAEERFKEIAEAYEVLSD-------------KKKRDIFDNY---------GEDGLK----------------GGQPGPDGGGQPGAYTYQFHG-DPRATFAQFFGSSDPFGAFFTGGDN-------------MFS-------GGQGGNTNEIFWNIGGDD-----------MFAFNAQAPSRKRQ-QDPPIEHDLFVSLEEVDKGCIKKMKISR-MATGSNGP-YKEEKVLRITVKPGWKAGTKITFPQEGDSAPNK-TPADIVFIIRDKPHSLFKREGIDLKYTAQISLKQALCGALVSVPTLQGSRIQVNPNH-EIIKPTTTRRINGLGLPVPKEPSRRGDLIVSFDIKFPDTLAPSLQNQLSELLPN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2U5-1", "uniprot_id": "Q9W2U5_DROME", "id": "Q9W2U5-1", "name": "J domain-containing protein", "aln": "------------------------------------------------------------------------MP----------------KDYYKILG----IQRTANDG-EIRKAYH--------------------------------------------KQALRYHPD-------------------KNKSPQAEEIFKQVAKAYEVLSD-------------KKKRGSYDSR---------NDKGTRRNTANQGSGFGDGTAFGSCGGGSGSGSGGGSGGGRQN-NPRANFGRFFDNSESYSTFFEDIEN-------------DFD-----------SDDDVLLGGGAG------------------APKRRCEQQSPQSSIEHVIYVALEDIANGCNRRMKISR-ASGRNGVDGVQYDRILTVKIPPGCKAGTKICFPNEGIQLPNL-EPANVVFIIRDKPHPIFRRDGNNLLYTAEISLKDALCGLHVMVPTLLGRPMELKTDVGEVISPKSVRRILGYGLPDSINNSRRGSIVVRFSIQFPDAISKELASSLDRLLQN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25294-1", "uniprot_id": "SIS1_YEAST", "id": "P25294-1", "name": "Protein SIS1", "aln": "------------------------------------------------------------------------MVK--------------ETKLYDLLG----VSPSANEQ-ELKKGYR--------------------------------------------KAALKYHPD---------------------KPTGDTEKFKEISEAFEILND-------------PQKREIYDQY---------GLEAARSGGPSFGP--GGPGGAGGAGGFPGGAGGFSGGHAFSNEDAFNIFSQFFGGSSPFGGADDSGFS-----------FSSYPSGGGAGMGGMPGGMGGMHGGMG-------------GMPGGFRSASSSPTYPEEETVQVNLPVSLEDLFVGKKKSFKIGR-----KGPHGASEKTQIDIQLKPGWKAGTKITYKNQGDYNPQTGRRKTLQFVIQEKSHPNFKRDGDDLIYTLPLSFKESLLGFSKTIQTIDGRTLPLSRVQ--PVQPSQTSTYPGQGMPTPKNPSQRGNLIVKYKVDYPISLNDAQKRAIDENF---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : : . : : : : * : .: : *. :: . . . : .. . .. * **.. ..: . : : : ::*::: * : ::* : . : : : * : **:: : .:* . : *::::* * ::*: :: : : : .:* : *: . : : : * * *:* . ::*.:.: :.: :* : : : ", "identical_positions": 24, "similar_positions": 91, "identity": "4.24%" }, { "cls_id": "homologset.agr.SGD:S000004954", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88844-1", "uniprot_id": "IDHC_MOUSE", "id": "O88844-1", "name": "Isocitrate dehydrogenase [NADP] cytoplasmic", "aln": "---------------------------------------------------------------MSRKIQGG-SVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFEAQKICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALEDVCIETIEAG-FMTKDLAACIKG-LPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75874-1", "uniprot_id": "IDHC_HUMAN", "id": "O75874-1", "name": "Isocitrate dehydrogenase [NADP] cytoplasmic", "aln": "---------------------------------------------------------------MSKKISGG-SVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAG-FMTKDLAACIKG-LPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7Z0E0-1", "uniprot_id": "B7Z0E0_DROME", "id": "B7Z0E0-1", "name": "Isocitrate dehydrogenase [NADP]", "aln": "MFALRRTAAMMTSVHRQPHLSQAVFRANFAISAADPKTHKISMDNERMSAVSEHSSVVCSPEQMAQKIKAG-PVVDVLGDEMTRIIWDSIKSQLILPFLDIELHTYDLGIENRDKTEDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFNLKKMWKSPNGTIRNILGGTVFREAIICKNVPRLVTGWQKPIVIGRHAHADQYKAVDYVVPGPGKLTLTWKGTDG-QVIDEVINDFK-GPGIALGMFNTDDSIVDFAHASFKYALDRKLPLYMSTKNTILKKYDGRFKDIFEDLYNKQYKKEYEAAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLLCPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNEPLKQFADTLEQVCIDTIESG-AMTKDLAICIKGNINAVTRRDYQETFEFINTLAKNLEGALAKNAVAAK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54071-1", "uniprot_id": "IDHP_MOUSE", "id": "P54071-1", "name": "Isocitrate dehydrogenase [NADP], mitochondrial", "aln": "------MAGYLRAVS-------SLCRASGSARTWAPAALTVPSWPEQP-----------RRHYAEKRIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVVDRAGTFKLVFTPKDGSSAKEWEVYNFP-AGGVGMGMYNTDESISGFAHSCFQYSIQKKWPLYLSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVQTVESG-AMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGKQ----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56574-1", "uniprot_id": "IDHP_RAT", "id": "P56574-1", "name": "Isocitrate dehydrogenase [NADP], mitochondrial", "aln": "------MAGYLRAVS-------SLCRASGSTRTWAPAALNVPSWPEQP-----------RRHYAEKRIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVVDRAGMFKLVFTPKDGSGAKEWEVYNFP-AGGVGMGMYNTDESISGFAHSCFQYSIQKKWPLYLSTKNTIMKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVQTVESG-AMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGKQ----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48735-1", "uniprot_id": "IDHP_HUMAN", "id": "P48735-1", "name": "Isocitrate dehydrogenase [NADP], mitochondrial", "aln": "------MAGYLRVVR-------SLCRASGSRPAWAPAALTAPTSQEQP-----------RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP-AGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESG-AMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGRQ----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53982-1", "uniprot_id": "IDHH_YEAST", "id": "P53982-1", "name": "Isocitrate dehydrogenase [NADP]", "aln": "----------------------------------------------------------------MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKATLDTVQVGGKMTKDLALMLGK----TNRSSYVTTEEFIDEVAKRLQNMMLSSNEDKKGMCKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. .:*:: *** **:**. **.:**:*.::::*: :**.: :** *:**** *.: * *:.*.:********* *::**:**:********************.** ::****. * *** *****..***:*.* .* . : :. ** : :* . *:.:.*:* :.** .**::.*: ::.: **:::*****:* **.:**:**:::::*.** .:: * *********** :**.***: * ********** :***:****:***:*: *****.*:**********:* :*:*. ****.*******:*.: :*.***.. : *.. **.. ::*:: * ****** : . : * :*:: : ..*. : ", "identical_positions": 199, "similar_positions": 122, "identity": "40.78%" }, { "cls_id": "homologset.agr.SGD:S000004957", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q50L42-1", "uniprot_id": "PA24E_MOUSE", "id": "Q50L42-1", "name": "Cytosolic phospholipase A2 epsilon", "aln": "MQSIPHSDEADVAGMTHASEGHHGLGTSMLVPKNPQG-EEDSKLGRNCSGFEDAQDPQTAVPSSPLLSMASCSSQEGSSPCHLLTVRIIGMKNVRQ---ADILSQTDCFVTLWLPTASQKKLKTRTISNCLHPEWDESFTFQIQTQVKNVLELSVCDEDTLTQNDHLLTVLYDLSKLCLRNKTHVKFPLNPE---GMEELEVEFLLEENFSSSETLITNGVLVSRQVSCLEVHAESRRPR---KRKKNKDLLVMVTDSFENTQRVPPCQEPCYPN------SACFHYPKYSQPQLYAEAPKSHCNFRL-----CCCGTHRNDPVCQPLNCLSDGQVTTLPVGEN----YELHMKSSPCSD-TLDVRLGFSLCQEEVEFVQKRKMVVAKTLSQMLQLEEGL---HEDEVPIIAIMATGGGTRSMVSLYGHLLGLQKLNFLDASTYITGLSGATWTMATLYSDPEWSSKNLETVVFEARRHVVKDKMPALFPDQLYKWREDLQKHSQEGYKTTFTDFWGKLIEYSLGDKKNE--------CKLSDQRAALCRGQNPLPIYLTIN--VKDD-VSNQDFREWFEFSPYEVG--MQKYGAFIPSELFGSEFFMGRLMKRIP-EPEMCYMLGLWSSIFSLNLLDAWNLSHT-----------------------SEEFFYRWTRERLHDIEDDPILPEIPRCDDNPLETTVVIPTTWLSNTFREILTRRPFV--------------SEFHNFLYGMQLHT--------DYLQNR--QFSMWKDT-------VLDTFPNQLTQFAKHLNLLDTA-FFVNSSYAPLLRPERKVDLIIHLNYCAG-----SQTKPLKQTCEYCTEQKIPFPSFSIL-EDDNSLKECYVMENPQ---EPDAPIVAYFPLISDTFQKYKAPGVER-SPDELELG--QLNIYGPKSPYATKELTYTEAAFDKLVKLSEYN-----ILNNRDKLIQALRLAMEKK-RMRSQCPS------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ANS2-1", "uniprot_id": "A0A8I6ANS2_RAT", "id": "A0A8I6ANS2-1", "name": "Phospholipase A2", "aln": "----------------------------MLQRQMPAW-VSHS-LSDTCQ----AED-------------GRCS-EEGSSPCHLLTVRIISMKNVRQ---ADILSQTDCFVTLWLPTASQKKLRTRTISNCPHPEWNESFTFQIQTRVKNVLEFSICDEDTLTQSDHLLTVLYDLSKLCLRNKTHVKFPLNPE---GMEELEVEFLLEENVSSSETLITNGVLVSRQVSCLEVHAESRRPR---KRKKNKNLLVMVTDSFENTQCVQPCLEPCCPN------PACFHYPKYSQPQLYAEAPKSHWSYRL-----CCCEAQRNDTVCQPLDCLSDGQPMTLPLGEN----YELHMKSSPCSN-TLDVRLGFSLCQEEVEFLQKRKVAVTKALNQVLQLEEGL---HEHEVPMIAIMATGGGTRSMVSLYGHLLGLQKLNLLDCSVYLTGLSGATWTMATLYSDPEWSSKDLEPVVFEARRHVVKDKMPALYPDQLCKWQEELRQHSQEGYKTTFTDFWGKLVEYSLGDKKNE--------CKLSEQRAALCRGQNPLPIYLTIN--VKDD-VSNQDFREWFEFSPYEVG--MQKYGAFIPTELFGSEFFMGRLMKRIP-EPEMCYMLGLWSSIFSLNLLDAWNLSHT-----------------------SEEFFYRWTREKLHDIEDDPLLPEIPRCDANPLETTVVIPATWLSNTFREILTHRPLV--------------SEFHNFLYGLQLHT--------DYLQNK--QFCMWKDT-------VLDTFPNQLTQFTKHLNLLDTA-FFVNSSYAPLLRPERKVDLIIHLNYCAG-----SQTKPLKQTCEYCTEQNIPFPNYSIQ-EDDKSLKECYVMENPQ---EPDAPIVVYFPLINDTFQKYKAPGVER-SPEELELG--QLNIYGPKSPYATKELTYTEAAFDKLVKLSEYN-----ILNNKDKLIQAVRLAMEKK-RMKSQCPS------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3MJ16-3", "uniprot_id": "PA24E_HUMAN", "id": "Q3MJ16-3", "name": "Cytosolic phospholipase A2 epsilon", "aln": "-------------MSLQASEGCPGLGTNVFVPQSPQTDEEGSRSGRSFSEFEDTQDLDTPG-LPPFCPMAPWGSEEGLSPCHLLTVRVIRMKNVRQ---ADMLSQTDCFVSLWLPTASQKKLRTRTISNCPNPEWNESFNFQIQSRVKNVLELSVCDEDTVTPDDHLLTVLYDLTKLCFRKKTHVKFPLNPQ---GMEELEVEFLLEESPSPPETLVTNGVLVSRQVSCLEVHAQSRRRR---KREKMKDLLVMVNESFENTQRVRPCLEPCCPTSACFQTAACFHYPKYFQSQVHVEVPKSHWSCGL-----CCR-SRKKGPISQPLDCLSDGQVMTLPVGES----YELHMKSTPCPE-TLDVRLGFSLCPAELEFLQKRKVVVAKALKQVLQLEEDL---QEDEVPLIAIMATGGGTRSMTSMYGHLLGLQKLNLLDCASYITGLSGATWTMATLYRDPDWSSKNLEPAIFEARRHVVKDKLPSLFPDQLRKFQEELRQRSQEGYRVTFTDFWGLLIETCLGDERNE--------CKLSDQRAALSCGQNPLPIYLTIN--VKDD-VSNQDFREWFEFSPYEVG--LQKYGAFIPSELFGSEFFMGRLVKRIP-ESRICYMLGLWSSIFSLNLLDAWNLSHT-----------------------SEEFFHRWTREKVQDIEDEPILPEIPKCDANILETTVVIPGSWLSNSFREILTHRSFV--------------SEFHNFLSGLQLHT--------NYLQNG--QFSRWKDT-------VLDGFPNQLTESANHLCLLDTA-FFVNSSYPPLLRPERKADLIIHLNYCAG-----SQTKPLKQTCEYCTVQNIPFPKYELP-DENENLKECYLMENPQ---EPDAPIVTFFPLINDTFRKYKAPGVER-SPEELEQG--QVDIYGPKTPYATKELTYTEATFDKLVKLSEYN-----ILNNKDTLLQALRLAVEKKKRLKGQCPS------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0C871-1", "uniprot_id": "PA24B_MOUSE", "id": "P0C871-1", "name": "Cytosolic phospholipase A2 beta", "aln": "-------------------------------------------------------------------------MQAKVPETCLLTVRVLRASGLPS---KDLVTSSDCYVTLNLPTASSHTLQTRTVKNSRNPVWNQNFHFRIHRQLKNVMELKVFDHDLVTRDDPVLSVLFDVGTLQIGTQR-QSFSLGTQ---EKGCLEVEFRLQTLTDCEEQLISNGIVVARELSCLHVELKRTGD----PKRSERKVQLVVAGACEGPQDASAGTG-----------SFHFHYPACWEQELNVHLQ-----------------DDPHEQLKVPLRTLPSSQLVRLVFPTSQEPLMRLELKKEEGPK-ELAVRLGCGPCPEEQAFLSKRKQVVAAALKKALQLDQDL---HEDEIPVIAVMATGGGIRAMTSLYGQLAGLQELGLLDCISYITGASGSTWALANLYEDPEWSQKDLAGPTEVLKTQVTKSKLGALAPSQLWRYRQELAERARLGHPTCFTNLWALINEALLHDKPHE--------HKLSDQREALSRGQNPLPIYCALN--SKEQGLSTFDFGEWCEFSPYEVG--FPKYGAFISSELFGSEFFMGRLVKQLP-ESRICFLEGIWSNLFAASLQDSLYWSSE-----------------------PSQ-FWDRWAQDQANLDKEQVP-------HLKIAEPPTMAG-RIAELFTDLLTKRPLA--------------HATHNFTRGLHFHK--------DYFQNS--HFSAWKAS-------KLDRLPNQLTPTEPHLCLLDVG-YLINTSCPPLLQPTRDVDLILSLDYNLY-----GAFQQLQLLSRFCQEQGIPFPSISPSPEEQRQPQECHLFCDPA---QPEAPAVLHFPLVNDSFQDYSAPGVPR-TSEEKAAG--EVNLSSSDSPYHYTKVTYSQEDVDKLLRLTHYN-----ICNNQDRLREAMHQAVQRRR-KRKQFRPE-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A1I6-1", "uniprot_id": "D4A1I6_RAT", "id": "D4A1I6-1", "name": "Phospholipase A2", "aln": "---------------------------------MALQ-------------------------------TCPVYMQAKVPETHLLTVRVLQASGLPS---KDLVTSSDCYVTLNLPTASSGTLQTRTVKNSRNPVWNQNFHFRIHRQLKNVMELKVFDQDLMTKDDPVLSVLFDVGTLQVGTQR-QSFSLSAQ---EDGRLEVEFRLQTLTDCEEQLISNGILVAQELSCLHVELKRTGD----PKRSERKVQLVVAAACEGPQEAPVGTG-----------SFRFHYPACWEQELSVHLQ-----------------DDPHEQLKVPLRTLPSSQLVRLVFPTSQEPLMRLELKKEDGPK-ELAVRLGCGPCPEEQAFLSKRKQVVAAALKKALQLDQDL---QEDEIPVIAVMATGGGIRAMTSLYGQLAGLKELGLLDCISYITGASGSTWALANLYEDPEWSQKDLAGPTEMLKTQVTKSKLGALAPSQLWRYRQELAERARLGYPTCFTNLWALINEALLHDKPHE--------HKLSDQREALSRGQNPLPIYCALN--SKEKGLSTFEFGEWCEFSPYEVG--FPKYGAFIPSELFGSEFFMGRLVKQLP-ESRICFLEGIWSNLFAASLQDSFYWSSE-----------------------PSQ-FWDRWAQDQANLDKEQVS-------HLKIAEPPTAAG-KIAELFTDLLTKRPLA--------------QATHNFMRGLHFHK--------DYFHHP--HFSTWKAS-------KLDKFPNQLTPAEPHLCLLDVG-YFINTSCPPLLQPTRDVDLILSLDYNLS-----GAFQQLQLVSRFCQEQGIPFPSISPSPEEQRQPQECHMFCDPA---QPEAPAVLHFPLVNDSFRDHSAPGVPR-TSEEKTAG--EVNLSSSNSPYDYTKVTYSQEDVDKLLRLTHYN-----ICNNQDRLREAMHQAVQRRR-NRRQFRRE-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C869-1", "uniprot_id": "PA24B_HUMAN", "id": "P0C869-1", "name": "Cytosolic phospholipase A2 beta", "aln": "------------------------------------------------------------------------MAVAEVSRTCLLTVRVLQAHRLPS---KDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQ---GEGRLEVEFRLQSLADRGEWLVSNGVLVARELSCLHVQLEETGD----QKSSEHRVQLVVPGSCEGPQEASVGTG-----------TFRFHCPACWEQELSIRLQ-----------------DAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMRVELKKEAGLR-ELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDL---QEDEIPVVAIMATGGGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTELLKTQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHD--------HKLSDQREALSHGQNPLPIYCALN--TKGQSLTTFEFGEWCEFSPYEVG--FPKYGAFIPSELFGSEFFMGQLMKRLP-ESRICFLEGIWSNLYAANLQDSLYWASE-----------------------PSQ-FWDRWVRNQANLDKEQVP-------LLKIEEPPSTAG-RIAEFFTDLLTWRPLA--------------QATHNFLRGLHFHK--------DYFQHP--HFSTWKAT-------TLDGLPNQLTPSEPHLCLLDVG-YLINTSCLPLLQPTRDVDLILSLDYNLH-----GAFQQLQLLGRFCQEQGIPFPPISPSPEEQLQPRECHTFSDPT---CPGAPAVLHFPLVSDSFREYSAPGVRR-TPEEAAAG--EVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYN-----VCNNQEQLLEALRQAVQRRR-QRRPH--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q50L43-1", "uniprot_id": "PA24D_MOUSE", "id": "Q50L43-1", "name": "Cytosolic phospholipase A2 delta", "aln": "--------------------MWSGDRRVGMESLSPER-------------------------------LHGHPYQEEASVFCRLTVKILEARSLPR---ADLLSQADPYVTVQLPTASGMKFKTQTVTNSSHPVWNETFSFLIQSQVKNILELTIYDEDVITKDDICFKVSYDVSEILPGQLLQKTFSLNPQ---GPEELDVELLMERTWDPPENLITNNVLVARELSHLDVSLDRAGNTAMAAGQDKLELELMLKGSYEDTQTFFPDTAF----------TFSFHYMRGQDTELNGYLRGPRNSG--------WNSDTSVTPFNVPLMSLAAGKEMTIDIPAMKAPEGKLQLKTDCCPK-ELSVRLSYGLCPEEQAFLSRRKKVVAAALKQALQLDEDL---NEDEVPVVGINAEGGGMRAMISLYGHLLALQKLGLLDCVTYFSGISGSTWTMAHLYRDPEWSQRDLEGPISHAREHVAKTLLKEFLPEHLASYRQTLKLREEQGYTVTVADLWGLVLESKLHGQVTD--------QKLSGQRAALERGQNPLPLYLSLN--VKENHLETLHFKEWVEFSPYEVG--FLKYGGFVPSELFGSEFFMGRLMKRLP-ESQICFLEGIWSNLFSVNLMDIWYDITY-----------------------GKD--SNNFPVDVRNSEKEFSGSAG---TSSGVEAPWLESGTALAQALKGFLTGRPFH--------------QRSANFLHGLQLHR--------DYCNQR--HFSTWADC-------NLDDTPNQLTPQDPQLCLIDAG-CFMNSSCPSLFRPGRQVDLIISFNYNQS-----LPFKGLQQSEKYSRARGLPFPRVEPSPEDHSQPQECYLFSDPT---CPEAPVVLHFPLVNDSFRDHSAPGVRR-SPDELKAG--QVNLTGAASPYFMYNMTYKNEDFDRLLQLSDYN-----VQNNQGTILQALRTVLKRRASETRPLGVKT----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZQH6-1", "uniprot_id": "D3ZQH6_RAT", "id": "D3ZQH6-1", "name": "Phospholipase A2", "aln": "--------------------MWSGDRRVVMESLSPER-------------------------------LPVYPRQEEASVFCQLTVKILEARSLPR---ADLLSKADPYVTLRLPTASGRKFKTQTVTNSSNPVWNETFSFLIQSQVKNILELTVYDEDLITKDDICFKISYDISEILPGQLVQKTFSLNPQ---GPEELDVEFLVERTCDPPENLITNNVLVARELSHLDVSLDRAGSTTMAAGQDKLELELMLKGSYEDTQTFLPDTAF----------TLSFHYMRSQDTELNGYLRSSRNSD--------WNSDTSATPFNVPLTLLAAGKEVTVDIPATKDPERKLQLKTDSCPK-ELSVRLSYGLCPEEQAFLGRRKKLVAAALKQALQLDEDL---KEDEVPVVGINAEGGGMRAMISLYGHLLALQKLGLLDCVTYFSGISGATWTMAHLYRDPEWSQKDLEGPISHAREHVAKSLLKEFLPEHLASYRQTLKLREEQGYTVTIADLWGLVLESKLHGQVTD--------QKLSEQRAALERGQNPLPLYLSLN--VKENHLETLHFKEWVEFSPYEVG--FLKYGGFVPSELFGSEFFMGRLMKRLP-ESQICFLEGIWSNLFSVNLMDIWYDITS-----------------------GRD--SNDFPVDVQNSEKEPSSSAG---VSSGVEAPWLQPGTALAQAFKGFLTGRPFN--------------QRSANFLHGLQLHR--------DYCNQR--DFSTWADC-------NLDDTPNQLTPQDPQLCLIDAG-CFMNSSCPSLFRSGRQVDLILSFNYNQS-----FPFKGLQQSGKYCSAQGLPFPRVEPSPEDHLQPQECYLFSDPT---CPEAPAVLHFPLVNDSFQDHSAPGVRR-SPDELKAG--QVDLTGVASPYFLYNMTYKNEDFDRLLRLSEYN-----IQNNQGTILQALKTVLKRRASETRPLGVKT----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86XP0-1", "uniprot_id": "PA24D_HUMAN", "id": "Q86XP0-1", "name": "Cytosolic phospholipase A2 delta", "aln": "-----------------------------MESLSPGG-------------------------------PPGHPYQGEASTCWQLTVRVLEARNLRW---ADLLSEADPYVILQLSTAPGMKFKTKTLTDTSHPVWNEAFRFLIQSQVKNVLELSIYDEDSVTEDDICFKVLYDISEVLPGKLLRKTFSQSPQ---GEEELDVEFLMEETSDRPENLITNKVIVARELSCLDVHLDSTGSTAVVADQDKLELELVLKGSYEDTQTSFLGTAS----------AFRFHYMAALETELSGRLRSSRSNG--------WNGDNSAGYLTVPLRPLTIGKEVTMDVPAPNAPGVRLQLKAEGCPE-ELAVHLGFNLCAEEQAFLSRRKQVVAKALKQALQLDRDL---QEDEVPVVGIMATGGGARAMTSLYGHLLALQKLGLLDCVTYFSGISGSTWTMAHLYGDPEWSQRDLEGPIRYAREHLAKSKLEVFSPERLASYRRELELRAEQGHPTTFVDLWALVLESMLHGQVMD--------QKLSGQRAALERGQNPLPLYLSLN--VKENNLETLDFKEWVEFSPYEVG--FLKYGAFVPPELFGSEFFMGRLMRRIP-EPRICFLEAIWSNIFSLNLLDAWYDLTS-----------------------SGESWKQHIKDKTRSLEKEPLTTSG---TSSRLEASWLQPGTALAQAFKGFLTGRPLH--------------QRSPNFLQGLQLHQ--------DYCSHK--DFSTWADY-------QLDSMPSQLTPKEPRLCLVDAA-YFINTSSPSMFRPGRRLDLILSFDYSLS-----APFEALQQTELYCRARGLPFPRVEPSPQDQHQPRECHLFSDPA---CPEAPILLHFPLVNASFKDHSAPGVQR-SPAELQGG--QVDLTGATCPYTLSNMTYKEEDFERLLRLSDYN-----VQTSQGAILQALRTALKHRTLEARPPRAQT----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q50L41-1", "uniprot_id": "PA24F_MOUSE", "id": "Q50L41-1", "name": "Cytosolic phospholipase A2 zeta", "aln": "-------MPWTLQPKWLAGKGLPLLGAILLRKTEKSE-------------------------------PQWKHRRQETHPYYDLQVKVLRARNIQH---TDKLSKADCYVRLWLPTASVSPSQTRTVVNSSDPEWNETFPYQIHGAVKNVLELALYDEDVLD-SDNVFSILFDTSTLQLGQPCTKNFTRQQ----DPKELEVEFTLEKSQTPASEVVTNGVLVAHPCLRIQGTVTGDKTASL-GELGSRQIQLAVPGAYEKPQ--PLQPTS-EPGLP---VNFTFHVNPVLSPKLHIKLQEQLQVFHSGPSDELEAQTSKMDKASILLSSLPLNEELTKLVDLEEGQQVSLRMKADMSSSGDLDLRLGFDLCDGEQEFLDKRKQVASKALQRVMGLSEAL---HCDQVPVVAVLGSGGGTRAMTSLYGSLAGLQELGLLDAVTYLSGVSGSSWCISTLYRDPSWSQKALQGPIKYASERVCSSKIGMLSPKQFEYYSREKRAWESRGHSMSFTDLWGLIIEYFLNQEENP--------AKLSDQQETVSQGQNPYPIYASIN--VHKN-ISGDDFAEWCEFTPYEVG--FPKYGAYVPTELFGSEFFMGRLLHFWP-EPRICYLQGMWGSAFAASLYEIFLKLGG-----------------------LSLSFLDWHRGSVSVTDDWPKLRKQ---DPTRLPTRLFTPMSSFSQAVLDIFTSRITC--------------AQTFNFTRGLCMYK--------DYTARK--DFVVSEDAWHSHNYGYPDACPNQLTPMKDFLSLVDGG-FAINSPFPLVLQPQRAVDLIVSFDYSLE-----GPFEVLQVTEKYCRDRGIPFPRIEVDPKDSEDPRECYLFAEAE---DPCSPIVLHFPLVNRTFRTHLAPGVERQTAEEKAFG--DFIINGPDTAYGMMDFTYEPKEFDRLVTLSRYN-----VLNNKETIRHALQLALDRRRQAGGRVGG------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z9B7-1", "uniprot_id": "D3Z9B7_RAT", "id": "D3Z9B7-1", "name": "Phospholipase A2", "aln": "-------MPWTLQPKWLASKGLPLLGAILLRETEKRE-------------------------------TQWKHWRQETHPYYDLQVKVLRARNIQH---TDKLSKADCYVQLWLPTASFSPTQTRTVVNCSDPEWNETFHYRIHSAVKNVLELALYDKDVLD-SDKIFSVLFDLSTLQLGQPYTKTFTQKQPGLTDPKELQVEFTLEKSQMPACEVITNGVLVAHPCLRIQGTVTGDKTASL-GEFGSREIQLAVPGAYEKPQSVPLQPTTVEPGLP---ATFIFHMNPVLSPRLNIALQEKLLVSHSGPSDELESQTSKMEEASILLSSLPLNQESTRLMNLEEGQQVTLRMKADMRSE-DLDLRLGFELCSGELEFLDKRKQVVSKALQQVMRLSEAP---HCDQVPVIAVLGSGGGTRAMTSLYGSLAGLQELGLLDAVTYLSGVSGSSWCISTLYKDPSWSQKTLQGPIRHASARVCSSKVGMLSPERFEYYTREKKTWESRGHSMSFTDLWGLIIEYFLNQEENP--------AKLSDQQEMVSQGQNPYPIYASIN--VHNN-ISGEDFAEWCEFTPYEVG--FPKYGAYVPTELFGSEFFMGRLLQHWP-EPRICYLQGMWGSAFAASLYEIFLKMRG-----------------------PRLGFLDWHRGTVSVTDDWPKLRKQ---DPTRLPTRLFTSKSFFSKAVLDIFTSRFTC--------------AQTFNFTRGLCLYK--------DYTARK--DFVVSEDAWHSDNYKHLDACPNQLTPMKDFLSLVDGG-FAINSPFPLILQPQRAVDLIVSFDYSLE-----APFEVLQVTEKYCRDRGIPFPRIEIDPKDSKDPRECYLFTEAE---DPCSPIVLHFPLVNRTFRKHLAPGVERQTAEEKAFG--DFIINGPDTAYGMMDFTYEPIEFDRLVTLSRYN-----VLNNIETIRRALQLALDRR-QAGGRAGA------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q68DD2-1", "uniprot_id": "PA24F_HUMAN", "id": "Q68DD2-1", "name": "Cytosolic phospholipase A2 zeta", "aln": "-------MLWALWPRWLADKMLPLLGAVLLQKREKRG-------------------------------PLWRHWRRETYPYYDLQVKVLRATNIRG---TDLLSKADCYVQLWLPTASPSPAQTRIVANCSDPEWNETFHYQIHGAVKNVLELTLYDKDILG-SDQLSLLLFDLRSLKCGQPHKHTFPLNHQ---DSQELQVEFVLEKSQVPASEVITNGVLVAHPCLRIQGTLRGDGTAPR-EEYGSRQLQLAVPGAYEKPQLLPLQPPT-EPGLP---PTFTFHVNPVLSSRLHVELMELLAAVQSGPSAELEAQTSKLGEGGILLSSLPLGQEEQCSVALGEGQEVALSMKVEMSSG-DLDLRLGFDLSDGEQEFLDRRKQVVSKALQQVLGLSEAL---DSGQVPVVAVLGSGGGTRAMSSLYGSLAGLQELGLLDTVTYLSGVSGSTWCISTLYRDPAWSQVALQGPIERAQVHVCSSKMGALSTERLQYYTQELGVRERSGHSVSLIDLWGLLVEYLLYQEENP--------AKLSDQQEAVRQGQNPYPIYTSVN--VRTN-LSGEDFAEWCEFTPYEVG--FPKYGAYVPTELFGSELFMGRLLQLQP-EPRICYLQGMWGSAFATSLDEIFLKTAG-----------------------SGLSFLEWYRGSVNITDDCQKPQLH---NPSRLRTRLLTPQGPFSQAVLDIFTSRFTS--------------AQSFNFTRGLCLHK--------DYVAGR--EFVAWKDT-------HPDAFPNQLTPMRDCLYLVDGG-FAINSPFPLALLPQRAVDLILSFDYSLE-----APFEVLKMTEKYCLDRGIPFPSIEVGPEDMEEARECYLFAKAE---DPRSPIVLHFPLVNRTFRTHLAPGVERQTAEEKAFG--DFVINRPDTPYGMMNFTYEPQDFYRLVALSRYN-----VLNNVETLKCALQLALDRH-QARERAGA------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q6G1-1", "uniprot_id": "A0A8M9Q6G1_DANRE", "id": "A0A8M9Q6G1-1", "name": "Phospholipase A2", "aln": "-------MFFSSFLESSVPTGLSCRNFRHMHDIMNKTTYVSCTVLRLHCR----------------PAEEKTMLKIELMPYWNLSVTVLRGTFSQS---YDVLSKNDCYVTLKLPTASACCHRTKTVKNSNEPKWNETFHFRVHSGIKNILEFHMFDADKLTKDDHLSTILFDISNLTPGQKQTKCFMSDDE---RRGALWVEFEMTVSSEKPIPYFSNGVLMAGPFCALDVKLQKHLKTN-----AENKMMLRLRGAYKEDCMILSSDENSSCLQN-----TCFYINRDLETEFSLLPPKAGAEMDEK------YANTADILSSVPMKPLSAKQQMKLSMPIAQG-EVHLELNTEDCLDEEMDVRLEFDIPVEEKNFLLKRRKVVSQALQKALNLGSAP---DPSKVPLVAVVCSGGGTRAMTATFGGLRALQTLQLLDAVSYITGVSGSTWTMASLYSDANWSNSDLNVAMESVKKEISKSVFSVFSPEQLQHYKEKMEEREKQGHLVSLIDMWGLAIEYLIHGKKKL--------GTLSDQQMALCNGQNPLPIYTALN--MKNGKTGCIIETEWCEFTPYEVG--FTKYGAFIPAQNYGSEYYLGHMVKKLP-EAGIYSLLGIWSSVFSLSLTQLWTVVTG-----------------------VIPSWASKVGEEVNHTDTDNKPSTS--------NTLHVNPMTELAKKLSNFLTSRPII--------------SQVFNFLRGFQLHR--------NYTENC--DFTAWKDT-------HPDAFPNSLTPADATLGLVDSA-FVLKSGFPPVLRSNRLADVILSLNYAWDS----DHFKILKETQEYCREHKTLFPKIDFKKLETEPIREVYVFEDEE---NPEVPIVLHFPLINVSFKQFKAPGKRREGKVEMKEGDFDVDFTRMFCPFSTLNLTYEPENFQKLSSLTAYN-----ILNNKDVILNALKKALKRNKEKNPITTNVSKF--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P47713-1", "uniprot_id": "PA24A_MOUSE", "id": "P47713-1", "name": "Cytosolic phospholipase A2", "aln": "----------------------------------------------------------------MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGTFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMD-ANYVMDETLGTATFPVSSMKVGEKKEVPFIFNQVT-----EMILEMSLEVCSCP-------------------------------------------------------------------------------------------------------------------------------------------------------DLRFSMALCDQEKTFRQQRKENIKENMKKLLGPKKSEGLYSTRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYIAGLSGSTWYMSTLYSHPDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIQNRMS--------MTLSSLKEKVNAARCPLPLFTCLH--VKPD-VSELMFADWVEFSPYEIG--MAKYGTFMAPDLFGSKFFMGTVVKKYE-ENPLHFLMGVWGSAFSILFNRVLGVSGSQNK------------GSTMEEELENITAKHIVSNDSSDSDDEAQGPKGTENEEAEKEYQSDNQASWVHRMLMALVSDSALFNTR-------EGRAGKVHNFMLGLNLNTSYPLSPLRDFSSQD--SFDD-ELDAAVADPDEFERIYEPLDVKSKKIHVVDSG-LTFNLPYPLILRPQRGVDLIISFDFSARPSDTSPPFKELLLAEKWAKMNKLPFPKIDPYVFDREGLKECYVFKPKNPDVEKDCPTIIHFVLANINFRKYKAPGVLRETKEEKEIAD-FDIFDDPESPFSTFNFQYPNQAFKRLHDLMYFN-----TLNNIDVIKDAIVESIEYRRQNPSRCSVSLSNVEARKFFNKEFLSKPTV---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50393-1", "uniprot_id": "PA24A_RAT", "id": "P50393-1", "name": "Cytosolic phospholipase A2", "aln": "----------------------------------------------------------------MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGTFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMD-ANYVMDETLGTATFPVSSMKVGEKKEVPFIFNQVT-----EMILEMSLEVCSCP-------------------------------------------------------------------------------------------------------------------------------------------------------DLRFSMALCDQEKTFRRQRKENIKENMKKLLGPKKSEGLYSTRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYVAGLSGSTWYMSTLYSHPDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIQNRMS--------TTLSSLKEKVSAARCPLPLFTCLH--VKPD-VSELMFADWVEFSPYEIG--MAKYGTFMTPDLFGSKFFMGTVVKKYE-ENPLHFLMGVWGSAFSILFNRVLGVSGSQNK------------GSTMEEELENITAKHIVSNDSSDSDDEAQGPKGTENEDAEREYQNDNQASWVHRMLMALVSDSALFNTR-------EGRAGKEHNFMLGLNLNTSYPLSPLRDFSPQD--SFDDDELDAAVADPDEFERIYEPLDVKSKKIHVVDSG-LTFNLPYPLILRPQRGVDLIISFDFSARPSDTSPPFKELLLAEKWAKMNKLPFPKIDPYVFDREGLKECYVFKPKNPDVEKDCPTIIHFVLANINFRKYKAPGVLRETKEEKEIAD-FDIFDDPESPFSTFNFQYPNQAFKRLHDLMYFN-----TLNNIDVIKDAIVESIEYRRQNPSRCSVSLSNVEARKFFNKEFLSKPTAESI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47712-1", "uniprot_id": "PA24A_HUMAN", "id": "P47712-1", "name": "Cytosolic phospholipase A2", "aln": "----------------------------------------------------------------MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMD-ANYVMDETLGTATFTVSSMKVGEKKEVPFIFNQVT-----EMVLEMSLEVCSCP-------------------------------------------------------------------------------------------------------------------------------------------------------DLRFSMALCDQEKTFRQQRKEHIRESMKKLLGPKNSEGLHSARDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYVAGLSGSTWYMSTLYSHPDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIHNRMN--------TTLSSLKEKVNTAQCPLPLFTCLH--VKPD-VSELMFADWVEFSPYEIG--MAKYGTFMAPDLFGSKFFMGTVVKKYE-ENPLHFLMGVWGSAFSILFNRVLGVSGSQSR------------GSTMEEELENITTKHIVSNDSSDSDDESHEPKGTENEDAGSDYQSDNQASWIHRMIMALVSDSALFNTR-------EGRAGKVHNFMLGLNLNTSYPLSPLSDFATQD--SFDDDELDAAVADPDEFERIYEPLDVKSKKIHVVDSG-LTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMNKLPFPKIDPYVFDREGLKECYVFKPKNPDMEKDCPTIIHFVLANINFRKYRAPGVPRETEEEKEIAD-FDIFDDPESPFSTFNFQYPNQAFKRLHDLMHFN-----TLNNIDVIKEAMVESIEYRRQNPSRCSVSLSNVEARRFFNKEFLSKPKA---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64GA5-1", "uniprot_id": "PA24C_MOUSE", "id": "Q64GA5-1", "name": "Cytosolic phospholipase A2 gamma", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELSSGVCPATRLQEAEKAAVHKRSPKVLEALRKLN--------IQADQAPVIAVLGSGGGLRAHIACLGVLSELKELGLLDAVTYLAGVSGSTWALSSLYTK----NGNMEGIEEELKHRYEKNEWDFHES-------LEKAIQASKRENYSLTDFWAYLIVSRQIRELQD--------SNLSSLKKQVEEGVLPYPIFAAIDEDLLADWRERKTQNSWFEFTPHHAG--YPALGAYVPITEFGSRFENGKLVKSEP-ERDLTFLRGLWGSAFADIKEIKNYILNYFRNPFGKLKFIEGPVTYSEAPRMNVDAMLLDLVMAYFTDMNDPSIKDKLCALQQALGTETDEFGIEMAEIIQNWNETSAEKKEQFLDHLLDRFKKTQEDTTTYSLMNWNTGLVWDRCVFVNETRKCVSKWQWGTVYNFLYKHGKIADETMCSRELLHLVDAG-FAINTPYPLVLPPVRETHLILSFDFSAG-----DPLETIRATADYCQRHEIPFPEVSEDQLKEWAKAPASCYVLRG----ETGPVVMHFTLFNKDNCGDDIETWRKKYGTVKLSDSYTPDLVRDLLRVSKENVKKNKINILSEMRKVAGNPGNIPRVNKEACLGDRVKDPQGSQTVEFKKSHNISKD--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UP65-1", "uniprot_id": "PA24C_HUMAN", "id": "Q9UP65-1", "name": "Cytosolic phospholipase A2 gamma", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSSEVSIIPGLQKEEKAAVERRRLHVLKALKKLR--------IEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQGLLDAVTYLAGVSGSTWAISSLYTN----DGDMEALEADLKHRFTRQEWDLAKS-------LQKTIQAARSENYSLTDFWAYMVISKQTRELPE--------SHLSNMKKPVEEGTLPYPIFAAIDNDLQPSWQEARAPETWFEFTPHHAG--FSALGAFVSITHFGSKFKKGRLVRTHP-ERDLTFLRGLWGSALGNTEVIREYIFDQLRN-LTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPPP----------EDEGGEPEHT--WLTEMLENWTRTSLEKQE-----------QPHEDPE-------RKGSLSNLMDFVKKTGICASKWEWGTTHNFLYKHGGIRDKIMSSRKHLHLVDAG-LAINTPFPLVLPPTREVHLILSFDFSAG-----DPFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKG----ETGPVVMHFPLFNIDACGGDIEAWSDTYDTFKLADTYTLDVVVLLLALAKKNVRENKKKILRELMNVAG-----------------LYYPKDS-----ARSCCLA----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53541-1", "uniprot_id": "SPO1_YEAST", "id": "P53541-1", "name": "Putative meiotic phospholipase SPO1", "aln": "-------------------------------------------------------------------------MQKLLFVFSVLLTVVLATAPFQVQCPSSPLIREAKHELCPEETLYLKKKKIKTKNKLIQFLKSLTEAKFSSKFYKRVLKDPPKIGIAISGGGYRSMLVGTGFISQMNDYGLFEYSDYIAGLSGGSWILMDLVVQN----------------------------------------------------------------------------------------------------------------------------------------------------------FEVKSLLQEWDLEEDLLLGIPEFDISEEEIVTNAKKEY----NDNDLKMKKRQGGSLITSSSNFYEQIEEIMN-----SIEEIP----EDYMITKRNLNPLARLKKIFFPNNTFTGTDAKIETFKKVLDFYKSLHLKIKPKKMEGFQISFTDYWGKAIVQRLKKNFDDDPNHSFSFSKLVNSSKKFKECSVPIPIFVANC-------KNGLLSNVIFEFTPFEFGSWENILRLFVKLPYLGSKIVSGKAEKCINNFDDLGFITATSSSIFNNVLIFIWNLASQ--------------------------------------------------------SSREAMKALNMVMGIFGLGKEEIFS------------------ISKDSSRLET--------DYAVYQPNPFYLYPEK-------------DNVLTNKNHLYLVDGGEDGENIPLRTLVIPERELDVIFVLDSSSD-----------IDNYPNGSKLKRIFEKLDEENVHYQFPNNVKTFTHPIVIGCNATKRTGHDSFLPIIIYHANANHGNASNTSTFKITYNQSEVSSMLPTGRGVFSNDYDLYYKNCLGCILTK-------RTMDRLPRKKKFSPFCLQCFKDYCYS------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . : *. : : : .. : :: . . : :. : * . * *:: **:*.. * :: **. * : : : . .. . . : . : ::* . : . . * .:*. :: * . . . : . ", "identical_positions": 16, "similar_positions": 54, "identity": "1.58%" }, { "cls_id": "homologset.agr.SGD:S000004961", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AQH6-1", "uniprot_id": "A0A8I6AQH6_RAT", "id": "A0A8I6AQH6-1", "name": "Cytotoxic granule associated RNA binding protein TIA1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDE-MPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDQ------------------TAGNDPYCFVEFHEHRHAAAALAAMNGR--------------------KIMGKEVKVNWATTPSSQ--------KKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYE------------------SNTKQLSYDEVVSQSSPGNCTVYCG---GVTS-GLTEQLMRQTFSPFGQIMEIRVFPDKGYSFIRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKETL-DMINP------------------------------------------------------VQQQNQIGYPPAYGQWGQWYG---------------------NAQQIGQYVP--NGWQVPAY--------GMYGQPWSQQGFNQTQS-SAPWMGPNYSVP------PPQGQNGG--MLPNQPAGYRVAGYETQ-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52912-1", "uniprot_id": "TIA1_MOUSE", "id": "P52912-1", "name": "Cytotoxic granule associated RNA binding protein TIA1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDE-MPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD-------------------TAGNDPYCFVEFHEHRHAAAALAAMNGR--------------------KIMGKEVKVNWATTPSSQ--------KKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYE------------------SNTKQLSYDEVVSQSSPNNCTVYCG---GVTS-GLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKETL-DMINP------------------------------------------------------VQQQNQIGYPPTYGQWGQWYG---------------------NAQQIGQYVP--NGWQVPAY--------GVYGQPWSQQGFNQTQS-SAPWMGPNYSVP------PPQGQNGS--MLPSQPAGYRVAGYETQ-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31483-1", "uniprot_id": "TIA1_HUMAN", "id": "P31483-1", "name": "Cytotoxic granule associated RNA binding protein TIA1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDE-MPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD-------------------TAGNDPYCFVEFHEHRHAAAALAAMNGR--------------------KIMGKEVKVNWATTPSSQ--------KKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYE------------------SNTKQLSYDEVVNQSSPSNCTVYCG---GVTS-GLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETL-DMINP------------------------------------------------------VQQQNQIGYPQPYGQWGQWYG---------------------NAQQIGQYMP--NGWQVPAY--------GMYGQAWNQQGFNQTQS-SAPWMGPNYGVQ------PPQGQNGS--MLPNQPSGYRVAGYETQ-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70318-1", "uniprot_id": "TIAR_MOUSE", "id": "P70318-1", "name": "Nucleolysin TIAR", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRR--VNSSVGFSVLQHTSNDPYCFVEFYEHRDAAAALAAMNGR--------------------KILGKEVKVNWATTPSSQ--------KKDTSN-----------HFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQE------------------TNTKQLRFEDVVNQSSPKNCTVYCG---GIAS-GLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESP-DMTKN------------------------------------------------------FQQ---VDYS-QWGQWSQVYG---------------------NPQQYGQYMA--NGWQVPPY--------GVYGQPWNQQGFGVDQSPSAAWMG-GFGAQ------PPQGQAPPPVIPPPNQAGYGMASFPTQ-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5BJN3-1", "uniprot_id": "Q5BJN3_RAT", "id": "Q5BJN3-1", "name": "Nucleolysin TIAR", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRR--VNSSVGFSVLQHTSNDPYCFVEFYEHRDAAAALAAMNGR--------------------KILGKEVKVNWATTPSSQ--------KKDTSN-----------HFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQE------------------TNTKQLRFEDVVNQSSPKNCTVYCG---GIAS-GLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESP-DMTKN------------------------------------------------------FQQ---VDYS-QWGQWSQVYG---------------------NPQQYGQYMA--NGWQVPPY--------GVYGQPWNQQGFGVDQSPSAAWMG-GFGAQ------PPQGQAPPPVIPPPNQAGYGMASFPTQ-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01085-1", "uniprot_id": "TIAR_HUMAN", "id": "Q01085-1", "name": "Nucleolysin TIAR", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMIT-------------------EHTSNDPYCFVEFYEHRDAAAALAAMNGR--------------------KILGKEVKVNWATTPSSQ--------KKDTSN-----------HFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQE------------------NNTKQLRFEDVVNQSSPKNCTVYCG---GIAS-GLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESP-DMTKN------------------------------------------------------FQQ---VDYS-QWGQWSQVYG---------------------NPQQYGQYMA--NGWQVPPY--------GVYGQPWNQQGFGVDQSPSAAWMG-GFGAQ------PPQGQAPPPVIPPPNQAGYGMASYQTQ-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QJJ0-1", "uniprot_id": "E9QJJ0_DANRE", "id": "E9QJJ0-1", "name": "Nucleolysin TIAR", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDESHPKTLYVGNLSRDVTENLILQLFTQIGPCKSCKMITEQSDSSRKMNSSSIGFSVLQHTSNDPYCFVEFFEHRDAAAALAAMNGR--------------------KILGKEVKVNWATTPSSQ--------KKDTSN-----------HFHVFVGDLSPEITTDDIRAAFAPFGKISDARVVKDMTTGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSVQD------------------NSAKQLRFDEVVNQSSPQNCTVYCG---GIQS-GLTEHLMRQTFSPFGQIMEIRVFPEKGYSFIRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKESP-DMAKN------------------------------------------------------VQP---MEYG-QWGQWNQMYG---------------------NPQQYGQYMT--NGWQVPSY--------GMYGQTWNQQGFGVEQSQSPAWVG-GFGTQ------PSQAQPG----AVMNQANFGMAGYQTQ-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IMX4-1", "uniprot_id": "Q8IMX4_DROME", "id": "Q8IMX4-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MDESQPKTLYVGNLDSSVSEDLLIALFSTMGPVKSCKIIRE--------------------PGNDPYAFIEYSNYQAATTALTAMNKR--------------------LFLEKEIKVNWATSPGNQP-------KTDISS-----------HHHIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPHTMKSKGYAFVSFVKKAEAENAIQAMNGQWIGSRSIRTNWSTRKLPPPREPSKGGGQGGGMGGGPGNGSGVKGSQRHTFEEVYNQSSPTNTTVYCG---GFPPNVISDDLMHKHFVQFGPIQDVRVFKDKGFSFIKFVTKEAAAHAIEHTHNSEVHGNLVKCFWGKENGGDNSANNLNAAAAAAAASANVAAVAAANAAVAAGAGMPGQMMTQQQIAAATGAAIPGQMMTPQQIAAQYPYAYQQMGYWYPPA----------------TYPTTQMQTQYMQ--QGYYPYAYPTSAQQAGGVPCIQFSAAGYRMVPP-NVAWGVPGTVVPGVTAAAASAAAAANGSLAPQMMYSAAMPQYQTQ-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JPX0-1", "uniprot_id": "A8JPX0_DROME", "id": "A8JPX0-1", "name": "RRM domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLTMSTLMMPAP---------TIAMG----APQITMGPHKPPET---KLLAIHPAAAAAAAAQQQQ-------------------QSVTAAHLQHNGQQQHSQQQQQQQMSQQQQQQQQQLVGNNSKPEQFHIFVGDLSAEIETQQLKDAFTPFGEISDCRVVRDPQTLKSKGYGFVSFVKKSEAETAITAMNGQWLGSRSIRTNWATRKPPATKADMN--------------------AKPLTFDEVYNQSSPTNCTVYCGGINGALSGFLNEEILQKTFSPYGTIQEIRVFKDKGYAFVRFSTKEAATHAIVAVNNTEINQQPVKCAWGKESGDPNHMSAIAGGAL--------------------------------------AQGFPFGSAAAAAAAAAYGQQVAG--YWYPPAPTYPA----------AAPASALQPGQFLQGMQGFTYGQFAGYQQAGYMGMGVQLPGTWQSVPPQPQLASAAAATAPQITQSVGSALPQAAGVVAYPMQQFQVSPQLAEDEWLAPSLLVXLPXGMAMYPTQQHQQQQQQQQQQQMLQQQHEQQTSGEYVKEPPYQTQQLQQLQHHQLQQQHSHNQHQQQQHYIHQLYYPSHWVQQQQQQQQQVANNEQQPQQQQQQPPVAQVYGMSEV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E1JIZ9-1", "uniprot_id": "E1JIZ9_DROME", "id": "E1JIZ9-1", "name": "", "aln": "MPASGNGCCSTRTAGCCQDCSGYQQGYEHLPVPRLQHQQPPPPLYQNQQQKQDHQQGSCTSTLQQTTTTTSNCSYGNCLMPAPATTSTYVSNIGTEPPLLSMQYCRSHCNMQHCNSTGGSNKAPAIYNNIPAQSMIFVPVMLPMQQQHPQQQQHDLHMQHPLTPSEDCKPLLHAKSVPPPPQPPPMLTHFQAMMQPPPLPPSPMMPPQSFG----CPLPSRTPATPPLPGTYRVQSLKSAAAAAVSAYQRNGKLPRNLPALRAMEMALRTNSFATPPAPHSLPLPPPHAARTEGGGQDMEDSDEEMEYMPPLHKQFHIFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEAESAITAMNGQWLGSRSIRTNWATRKPPASKE--N--------------------IKPLTFDEVYNQSSPSNCTVYVGGVNSALT-ALSEEVLQKTFAPYGAIQEIRVFKDKGYAFVRFSTKEAATHAIVGVHNTEINAQPVKCSWGKESGDPNNAQTIATQALNSAAAA--------------------------------AAGFPYG-VGAAAAAAAYGQQLAATGCWYSPTPTYPASSATAAAVTPAAASAAAVQNQFLQGIQGYHFGQYGGYQQG-YMGMGVQIPATWQGVTQAQISPAQQLATG-----VAGTAIPQAAGVVAYPIQQFQVSPQVYP----------------------------------LLLQAQ-----------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32588-1", "uniprot_id": "PUB1_YEAST", "id": "P32588-1", "name": "Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1", "aln": "-----------------------------------------------------------------------------------------------MSENNEEQHQQQQQQQPVAVETPSAVEAPASADPSSEQSVAVEGNSEQAEDNQGENDPSVVPANAITGGRETSDRVLYVGNLDKAITEDILKQYFQVGGPIANIKIMIDK------------------NNKNVNYAFVEYHQSHDANIALQTLNGK--------------------QIENNIVKINWAFQSQQS----------SSDD-----------TFNLFVGDLNVNVDDETLRNAFKDFPSYLSGHVMWDMQTGSSRGYGFVSFTSQDDAQNAMDSMQGQDLNGRPLRINWAAKRDNNNNNNYQQR----------------RNYGNNNRGGFRQYNSNNNNNMNMG--MNMNMNMNMNNSRGMPPSSMGMPIGAMPLPSQGQ------PQQSQTIGLPPQVNPQAVDHIIRSAPPRVTTAYIGNIP------------------------------------------------------HFATEADLIPLFQNFGFILDFK-------------------HYPEKGCCFIKYDTHEQAAVCIVALANFPFQGRNLR-TGWGKERSNFMPQQQQQGGQP------LIMNDQQQPVMSEQQQQQQQQQQQQ---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * : : . . . . .. .::*****. :: : :: ** * . ::: * * .*:**.**** .: :*:.*: * ** :..* :* **:::: . . . . .* * .: * . :. * : .:* .::: : .: .. : ::. : . . : . ", "identical_positions": 33, "similar_positions": 70, "identity": "3.93%" }, { "cls_id": "homologset.agr.SGD:S000004965", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GK59-1", "uniprot_id": "A0A8I6GK59_RAT", "id": "A0A8I6GK59-1", "name": "non-specific serine/threonine protein kinase", "aln": "MKKFS---RMPKSEG-SGGGAAAGGAAGSGLGGGFGS--SSMGVRVFAVGRYQVTLEESLAEGGFSTVFLVRTHSG------IRCALKRMYVNNTPDLNICKREITIMKELSGHKNIVGYLDC-AVNSIS-DNVWEVLILMEYCRAGQVVNQMNKKLQTGFTESEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLNDAGNYVLCDFGSATNKFLNPQ-KDGVNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFALPFGES-QVAICDGSFTIPDNSRYSHNVHCLIRFMLEPDPEHRPDIFQVSYFAFKFAKKDCPVSNINNSILPSTLPEPMTATEAAARK-----SQMKARITDTIGPTETSIAPRQRPKAN--STAAISSVLTIQSSATPVKVPAPGEFSNHKPKGALRPGNGSDILMVQGPTQQPPQQHRVLQQLQQGDWRLQQLHL-HRHP------QQQQQQQQQQQQ--------------QQQQQQQQQQ---------------------------LLQNAYLQQYQHAMHQQQILQQQFLMHSVYQPQPLASQYPTMMQQYQQALLQQQMLAHHQQPAQQVSPEYLTSP---------------QEFSPALAPYGSSLPAQVGTIVDSSYGATSRSVAEKEAVANFTNQKTISHPPDMSGWNPFGEDN--FSKLTEEELLDREFDLLRSNRLGESTPSDKNVDPPPAPHSRPPEEPFASVPFISHSGSPEKK-TEHSPNQKNITAHPTKNGSS------SPICK-----AGQKTSENPVVRGHAQ----------------------------------------------------------------KGNDESESEFESDPPSPKSSEEEQEDED--AQGEHGDFNDEDTEPENLGHRPLLMDSEDEEEDD---------------KHSSDSECEQAKAKGGESSSLRRNKPGGAP-----------EPASSP--ALTPSQEFDVFGAVPFFAVPAP-ELQHRGSGKSVSQQMFP-------EQEEYDVFTKAPFSKKVTVQDWPAVRPDTRPLPARP----------------------------RSVDIFGSTPFQPF------------STAASKSESKEDVFGLVPFEEITGSQQQQQKVKQRSLQKLSSRQRRTKQDVSKSNGK-----RHHGTPTSAKKPLKPPYRTPERARRHKRVGRRDSQSSNEFLTISDSKENISVALTDGKDRASVLPPDESLLDPFGAKPFHP---------------------------------------------------------------------------------------------PDL-WHQTHQGLSDICVDHTAILPGRPRQNSVHGSFHSADALRMDDFGAVPFTELVVQSVSP---QQSQPVELDPFGAAPFPSKQ--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91Z96-1", "uniprot_id": "BMP2K_MOUSE", "id": "Q91Z96-1", "name": "BMP-2-inducible protein kinase", "aln": "MKKFS---RMPKSEG-SGGGAAAGGAAGGGLGGGFAS--SSMGVRVFAVGRYQVTLEESLAEGGFSTVFLVRTHSG------IRCALKRMYVNNTPDLNICKREITIMKELSGHKNIVGYLDC-AVNSIS-DNVWEVLILMEYCRAGQVVNQMNKKLQTGFTESEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLNDAGNYVLCDFGSATNKFLNPQ-KDGVNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLPFGES-QVAICDGSFTIPDNSRYSHNVHCLIRFMLEPDPECRPDIFQVSYFAFKFAKKDCPVSNINNSFLPSTLPEPMTATEAAARK-----SQMKARITDTIGPTETSIAPRQRPKAN--STAATSSVLTIQSSATPVKVPAPGEFSNHKPKGALRPGNGSEVLMVQGPPQQPPQQHRVLQQLQQGDWRLQQLHL-HRHPHHHHQQQQQQQQQQQQQQ--------------LQQQQQQQQQ---------------------------LLQNAYLQQYQHAMHQQHILQQQFLMHSVYQPQPPASQYPAMMQQYQQAFLQQQMLARHQQPAQQVSPEYLTSP---------------QEFSPALVSYASSLPAQVGTIVDSSYGAN-RSVAEKEAVANFTNQKTISHPPDMSGWNPFGEDN--FSKLTEEELLDREFDLLRSNRLGASTPSDKTVDLPPAPHSRPPEEPFASVPFISHSGSPEKKTTEHSPNQKSITANLTKNGGS------SPLCKDQ--RAGKKTSENPVIRGQVQ----------------------------------------------------------------KGHDDSESDFESDPPSPKSSEEEQEDED--AQGEHGDFNDDDTEPENLGHRPLLMDSEDEEEDD---------------KHSSDSECEQAKTKRGDTSSLRRDKPGVAPDTAL------LTPARSPADALTPSQEFDVFGAVPFFAAPAPQSLQHRGDGKNLSQHAFP-------EQEDFDVFTKAPFNKKVSVQDWPAVGPDARPLPARP----------------------------RSVDIFGSTPFQPF------------SVSASKSESKEDVFGLVPFEEITGSQQQQ-KVKQRSLQKLSSRQRRTKQDVSKSNGK-----RHHGTPTSAKKTLKPPYRTPERARRHKKVGRRDSQSSNEFLTISDSKENISVALTDGKDRASVLPSDESLLDPFGAKPFHP---------------------------------------------------------------------------------------------PDL-WHQPHQGLSDICVDHTTILPGRPRQNSVHGSFHSAETLRMDDFGAVPFTELVVQSVTP---QQSQPVELDPFGAAPFPSKQ--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NSY1-1", "uniprot_id": "BMP2K_HUMAN", "id": "Q9NSY1-1", "name": "BMP-2-inducible protein kinase", "aln": "MKKFS---RMPKSEGGSGGGAAGGGAGGAGAGAGCGSGGSSVGVRVFAVGRHQVTLEESLAEGGFSTVFLVRTHGG------IRCALKRMYVNNMPDLNVCKREITIMKELSGHKNIVGYLDC-AVNSIS-DNVWEVLILMEYCRAGQVVNQMNKKLQTGFTEPEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQ-KDGVNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLPFGES-QVAICDGNFTIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAKKDCPVSNINNSSIPSALPEPMTASEAAARK-----SQIKARITDTIGPTETSIAPRQRPKANS-ATTATPSVLTIQSSATPVKVLAPGEFGNHRPKGALRPGNGPEILLGQGPPQQPPQQHRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQQQQQQQQQQQQ--------------QQQQQQQQQQHHHH-------------------HHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQMLAQHQPSQQQASPEYLTSP---------------QEFSPALVSYTSSLPAQVGTIMDSSYSAN-RSVADKEAIANFTNQKNISNPPDMSGWNPFGEDN--FSKLTEEELLDREFDLLRSNRLEERASSDKNVDSLSAPHNHPPEDPFGSVPFISHSGSPEKKAEHSSINQENGTANPIKNGKT------SPASKDQ--RTGKKTS----VQGQVQ----------------------------------------------------------------KGNDESESDFESDPPSPKSSEEEEQDDEEVLQGEQGDFNDDDTEPENLGHRPLLMDSEDEEEEE---------------KHSSDSDYEQAKAKYSDMSSVYRDRSGSGPTQDLNTILLTSAQLSSDVAVETPKQEFDVFGAVPFFAVRAQQPQQEKNE-KNLPQHRFPAAG---LEQEEFDVFTKAPFSKKVNVQECHAVGPEAHTIPGYP----------------------------KSVDVFGSTPFQPF------------LTSTSKSESNEDLFGLVPFDEITGSQQQK--VKQRSLQKLSSRQRRTKQDMSKSNGK-----RHHGTPTSTKKTLKPTYRTPERARRHKKVGRRDSQSSNEFLTISDSKENISVALTDGKDRGNVLQPEESLLDPFGAKPFHS---------------------------------------------------------------------------------------------PDLSWHPPHQGLSDIRADHNTVLPGRPRQNSLHGSFHSADVLKMDDFGAVPFTELVVQSITPHQSQQSQPVELDPFGAAPFPSKQ--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UHJ0-1", "uniprot_id": "AAK1_MOUSE", "id": "Q3UHJ0-1", "name": "AP2-associated protein kinase 1", "aln": "MKKFFDSRREQGSSGLGSGS-SGGGGSSSGLGSGYIG-------RVFGIGRQQVTVDEVLAEGGFALVFLVRTSNG------VKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDS-SINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQ-AEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPFGES-QVAICDGSFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPVPNVQNSPIPAKLPEPVKASEAAVKK-----TQPKARLTDPIPTTETSIAPRQRPKAG--QTQPNPGILPIQP-ALTPRKRATVQPLPQAAGPSNQPGLLPSVSQPKAQATPSQPLQSSQPKQPQAPPTPQQTPATQTQGLPTQAQATPQHQQQHLLKQQQQQQQQ-----PQQPTAPPQPAGTFY-------------------QQQQQQQQQQAQTQQFQAVHPAAQQPVTAQFPVGSQGGAQQQLMQNFYHQQQQQQQQQQQLMAQQAALQQKTAVVVPQ---------------SQAQPATAPQAAAAQEPGQIQAPVRQQPKVQTTPPPTIQGQ---KVGSLTPPSSPKT-QRAGHRRILSDVTHSAVFG--VPASKSTQLLQAAAAEASLNKSKSATTTPSGSPRTSQQ----------------------NVSNASEGST------WNPFDDD--NFSKLTAEELLNKDFAK----------------------------------------------------------------LGEGKLPEKLGGSAESLIPGFQPTQGDAFTTPSFSAGTAEKRKGGQAVDSGIPLLSVSDPFIPL-------------QVPDAPEKLIEG--LKSPDTS-LLLPDLLPMTDP----------FGSTSDAVIDK-ADVAVESLIPGLEPPVAQRLPSQTESVTSNRTDSLTG-----EDSLLDCSLLSNPTAGLLEEFAPIALSAPTHKAAE-----------------------------------DSNLISGF------------GVAEGSEKVAEDEFDPIPVLITKNTQG--------GHSRNSSGSSE------------------SSLPNLARSLLLVDQLIDL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C1X8-1", "uniprot_id": "AAK1_RAT", "id": "P0C1X8-1", "name": "AP2-associated protein kinase 1", "aln": "MKKFFDSRREQGSSGLGSGS-SGGGGSSSGLGSGYIG-------RVFGIGRQQVTVDEVLAEGGFALVFLVRTSNG------VKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDS-SINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQ-AEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPFGES-QVAICDGSFTIPDNSRYSQDMHCLI-YMLEPDPDKRPDIYQVSYFSFKLLKKECPVPNVQNSPIPTKLPEPVKASEAAVKK-----TQPKARLTDPIPTTETSIAPRQRPKAG--QTQPNPGILPIQP-ALTPRKRATVQPLPQATGPSNQPSLLASVSQPKAQATPSQPLQSSQPKQPQAPPTPQQTPAPQTQGLPTQAQATPQHQQQLLLKQQQQQQQQQQQQQPQQPTAPPQPSGTFY-------------------QQQQPQQQQAQTQQQFQAVHPAAQQSVTAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQLMAQQAALQQKTAVVVPQ---------------PQAQPATAPQAAAAQEP-QIQAPARQQPKVQTTPPPTIQGQ---KVGSLTPPSSPKT-QRAGHRRILSDVTHSAVFG--VPASKSTQLLHAAAAEASLSKSKSATTTPSGSPRTSQQ----------------------NVSNASEGST------WNPFDDD--NFSKLTAEELLNKDFAK----------------------------------------------------------------LGEGKLPEKLGGSAESLIPGFQATQGDAFATSSFSAGTAEKRKGGQAVDSGIPLLSVSDPFIPL-------------QVPDAPEKLIEG--LKSPDTS-LLLPDLLPMTDP----------FGSTSDAVIEK-ADAAVESLIPGLEPPVAQRLPSHTESVTSNRTDSLTG-----EDSLLDCSLLSNPTADLLDEFAPIALSASTHKAAE-----------------------------------DSNLISGF------------GVAEGSEKVAEDEFDPIPVLITKNTQG--------GHSRNSSGSSE------------------SSLPNLARSLLLVDQLIDL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3B6K5-1", "uniprot_id": "A0A8M3B6K5_DANRE", "id": "A0A8M3B6K5-1", "name": "non-specific serine/threonine protein kinase", "aln": "MKKFFDSRRELVGSGPGSGGGAGGSGSGSGAGGNFIG-------RNFTVGRHQVTVEETLAEGGFAIVFLVRTNQG------VRCALKRMYVNNEHDLQVCKREIQIMRDLNGHKNIVGFLDS-SITAVGGGDVWEVFILMDFCRGGQVVNLMNQRLQTGFSEQEALQIFCDTCEAVARLHQYKTPIIHRDLKVENILLHDRGHYVLCDFGSATMKFQNPQ-SEGVTAVEDEIKKYTTLSYRAPEMVNLYNGKIITTKADIWAMGCLLYKLCFFTLPFGES-QVAICDGNFTIPDNSRYSQDMHRLIRYMLEPDPDKRPDIYQVSFFAFKLARRDCPVQNVKNSPIPAKLPEPIRASEAAAKKS---QTQTKARLTDPIPTTETSITPRQRPKAAQSQSQALGGILPIQPAALTPRKRANLP-----AG-AAQP-IAVSVN----FAQPAAALQS---QKAQASPAPQQ----KTQPIPVTVTATAG----------------------GIPAASPTP--------------------------------------QKAVATPPPSSPAPPTAPARSAR------------RKQASVAQQQSVVAPPTATQP--AVAQPP---------------AQAEPTAAP--PTVQQP----APQSQISPEDAEERPAAPG------LSQTPPSSPRTAQKAGHRRIQSDVTHSAMFG--VPVSQSTQQLQAATAEASLNKSKSASATPSNSPQSSQQSVYQPAQQQASVSVPQAPASAANLTSPPTQPT------WNPFDDD--NFSKLTAEDLLNKDFTK----------------------------------------------------------------LAD-EPVEPLIVTSDSLIPGLEAAE-------SAPPSSAERPADILGLEPGAGLLAV-------------------------PEKLIEG--LKSPDTS-LMLPDLLSMADP----------FGSSIEETRDVNTDVCLDSLIPGLEPPQAQLQPVEAESASLVLTDPLIG-----DDSLLGG-PLSSSSASCLDDFAVLSGGPSQNIPAA-----------------------------------EPCLISGF------------EPS-SAETANEDEFDPIPVLVSKNSQDDL--PSVNGYESASCIQSSDVPAEEEEEEEVLHMCSGSKLPLLDSKLLNTTSLKLSPSSSPDVFSSAPFPG------CGPDSRDIFTSAPFPQIQPSHPQPDVFLQAPFYKRSESH---------------------------------------------------------------------------------------------VAQISNGDDPVLPHPPVHSQIRFPYCAEA-PMPQQPIAAHRVVSSVGQQAAISSVPVGPLHS--WTVGVRAVMDPFLAAPFQPRGPLGKP---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BFD5-1", "uniprot_id": "A0A8M2BFD5_DANRE", "id": "A0A8M2BFD5-1", "name": "non-specific serine/threonine protein kinase", "aln": "MKKFFDARREMVSSGPASGAGAGGGAGS----GAFIG-------RVFSIGRYQVTVEETVAEGGFAIVFLVRTHQG------VRCALKRMYVNNEHDLQVCKMEIQIMRDLVGNKNIVGFLDS-SITAVGSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFSESEVLQIFCDTCEAVARLHQCKPPIIHRDLKVENILLHDRGHYVLCDFGSAINRSQNPQ-TEGVAVVEEEIKKYTTLSYRAPEMVNLYGGMVITTKADIWALGCLLYKLCYFTLPFGES-QVAICDGSFTIPDNSRYSHDMHCLIRYMLEPDPDMRPDIFQVSYFAFKLSRRDCPVQNVHNSPIPTKLPEPIRASEAVAKK-----SQNKARLTDPVPTTETSIAPRQRPKAG--QAQPITGILPIQP-ALTPRKRPSAP---------PGPSQPISVN---MASQPPVAQQQATPSPPQTTPQHAQLFVQQQNTAFFTAQQQQNHSTQT-----------------QMPAASPSTQ----------------------------------SKPKNRAPPPPMHHPQPDRLTTLSATT----------QTKPKAMAPAPPAESSHSVDGEASVSAQPKTK-------------AMAPPPPASHASTTLPPPNSTSAASTYSGGEPEQRSAAGSRGVHKVGSLTPPSSPKAAPKGGHRRILSDVTHSTIFG--VPVSKSTQLLQAAAAEASLNKSKSASTTPSGSPCSSQQSVYQP----------------ADASGHSAGATGS----WNPFGDD--NFSKLTAEELLNKDFAK----------------------------------------------------------------LDAKTAER---SCPENLISGLQSVS--------SNKGFLQGGAGMDSLIPGLDPLQTDLKSAALP------------ECLVGRDSLLDGSLLSHPSAGGLLLSSPSSLPVP----------SVDQFTALSSGPSHQASDQNHP-LSGFQSSETGDQSSDNQFDPIPVLNS-----KSSSQEAEGKSD-GYGIADDDENPTEEDFPHSSDE-----------------------------------DDAEKGGR------------SQVSGDETPSLDCSGSRPLLQDSDDED--------EQSPASSRNLR----------------MSSASEVASENQSEIQAQRSGADPSVDVFSKAPFRIGQNLDDNNSNEGDVFTNAPFLRPP---AQPDIFLQAPFGRKKEAS---------------------------------------------------------------------------------------------GKVYTN---PVIHPMFLQGSSIDQSILGP-VAPLQFQPQELSKYSRHYEEPVNSDPEHNMAS--DMSSG----DPFVSAPFHLKGRHEKR---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJ30-1", "uniprot_id": "Q9VJ30_DROME", "id": "Q9VJ30-1", "name": "non-specific serine/threonine protein kinase", "aln": "MKKILS-KFERNENSRLENPPNSSSSSSSNEKNSFVG-------KVFTVGRVTVTVEDVLAEGGFAMVFLARGNGGG-SSSATKYALKRMYVNNEHDLNVAKREIQIASNLSGHKNIIGYVDS-SITPTG-NGVCEVLLLMPYCK-HHMLAMMNARLHVGFTEPEVLNIFCDIAEAVSRLHYCQTPIIHRDLKVENILQTDAGNFVLCDFGSATAKTLNPQ-QHGVTVVQEEIQKYTTLSYRAPEMIDLYGGKSITTKADIWALGCMLYKLCFFSLPFGES-TLAIQNGQFSIPDSSKYSKGMHQLIKYMLEPDMEKRPNIWQVCEVAFRLAGKDNPVQNLHKTPIPNFDLLVVPPFESEAKRISAAASKAAKAQNVSVVEAGTSVAPRSRPKGSSSVHGGNPLGLGLPPSPSPRQNITSPQPQPQPVVEQFQANFPAMPPAVPPPPQAVTPAAPAASKLFESSGYPDPFNEPAAAVIPTEFLPAAEEPNKEEVPQDLNVIAGTPTKSMLTPPKPSGGGGHRRNVSDTSAFNKTFANETSQFLAPFNNNLAAMGDGQQTLASAASNPGIYASSTANSAAVSISELMKPGQTAVEKRVEAWNPFEEEQPFSQMTEDHIFEAEFDKIRQRGSQGSITAKSASTTSTLTPTEQIPSAVVAPVTAAPGAVPPPPIAAAVSPYPSQVSEDPFGSAPFSLPPGLREKASSLRKTGAKFIGVSSGGTGGGVATPIGLVAGGANTATSSNSSKWMLSPTLEVSSEEKTSLISKLKTDSECGIPGAVGGAGEGVSGYVKLPVEDRN--KYEKLRSKDQPTSDDSDSEASEFFQQDSDEGGGGIFRQMQMVTSNLPETIHKIQQVAYHKVDKTAHLPIVKKLRDKTKKPTTAAHQAAQQLNLMAAAVAAQAEEAAKAAESDGDSIGSASDLRAEDDDLFDENPRQTQAKQRRPLPTEMDGISESVKTCSSSAYHAECESVTTHEDDVRSRVVVKVRMRKKDRALVTATGDPSAPSEELSPTSSDLLHKFGDRPLLLDDELDYGSGESKSSTESPVAPILPTNPDVQESEEDVFALAPFKLPVGVPLKRKTKPKAKPKPSEPEMWTSTPVKSAAVGDPSTNFASFPAQLTPTNNVGNSAQLDEFNEPIFNPFQENAQNTQSGETNQCDLFGLEPFPQVIRTIEQNPQHHQIHQFPSHNNNNNVIKVPASVSVALPASVPVSVSVNSSAPQLVTINHSIIINKTPEPPMNYNNNNNNQTAKSSGTSSVYVNVPSFSSMSTSSCSINQPQSSPAAVIPVQAPLPVPVPAPVSVPAVPVPIPAVVTHLRPLLPIADNAYVQISQDRCSDFTPDDEEEPVVLRDADVVADGIGIPTPAKPKKEKSNLAVRVLPGKLTQKVKGHSYKKVSAAALGSTSSLSSGSKQKHQRLQYQSHDDDDDEQDQDENRGAGGGRNFQSNTIQNSAKTGFSNMSFEDFPSDQEMDRLSRTIPFEVVRNEKMLLEAEKKFGSLKRRNNLFS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53974-1", "uniprot_id": "ARK1_YEAST", "id": "P53974-1", "name": "Actin-regulating kinase 1", "aln": "-------------------------MNQPQIGTYNVG-------TQLTVGSHQVEIIKYLTSGGFAQVYSALINPPDPHSNSSVACLKRVIVPDKPSLNTLRAEVDAMRLLKNNRYVVSYIDSHAAKAMLHNGSYEVFVLMEYCERGGLIDFMNTRLQNRLHEFEILQIMSQVTQGVAAMHALQPPLIHRDIKIENVLISANNEYKLCDFGSVCGIIRPPRNSQELSYVQQDILKNTTAQYRSPEMIDTFRGLPIDEKSDIWALGIFLYKLCYYTTPFEKGGDLAILSGKFEFPLYPNYSEQLKGLIRDILVQDPRHRPNVYQLLKRISIMQNVPCPINDIQVVQAPSSHLNLTELHQLSATQN---------ILSLNSPTTMENTMPNATFQIS---MADNTTTAQMHPNRKPSQIAYDAS-----------------------FSNSAKGSQPLFDKSQN----------------------------------------------------------------------------------------------MYHALDPPLVEPLASSVSN-----------------NDNELKANSATKLKQAIVSEAHTFRQNN---------------------------SIDFPLQNIIPQYEDSSSSSDES----------------------------------------YSGDVDELKKTRSLGSYSTRGNIKKNQSVKESLTSSSLPGTS-----------------------FTPTSTKVN--------LKHENSP---------------------------------------------------------------------------------------------FKSTFVNTIDNSKDD-----LNKPSYEDLDVSKQNLKN---------------------------------------------SIQQRMIDKLNSSEES-----------FNARKMSKVKLHEKGEIDKPTMLKSSGPISKDKKTKPTPPPKPSHLKP---------------KPPPKPLLLAGRKLSLDK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :* * : . ::.***: *: . .***: * : .*: : *: * .:: ::.::*. : . .. **::** :*. :: ** :*: : * * *:*:.: :.*: :* :.*:****:*:**:* ..: ******. *: . : *:::* * ** .**:***:: : * * *:****:* :*****::: ** :. :** .*.* :* ..**. :: ** :* * **:::*: : *: ::: * : . : . : . *. : : . . : . . : . . : . . . . : . : . : : . . : . . ", "identical_positions": 86, "similar_positions": 129, "identity": "5.72%" }, { "cls_id": "homologset.agr.SGD:S000004966", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q569C4-1", "uniprot_id": "HDA10_RAT", "id": "Q569C4-1", "name": "Polyamine deacetylase HDAC10", "aln": "---------------------------------------------------------------------------------------------------------MGTALVYHEDMTATRLLWDDPECEIECPERLTAALDGLRQRGLEER------------CQCLSVCEASEEELGLVHSPEYIALVQKTQTLDKEE------------------LHTLSKQYDA----VYFHPDTFHCARLAAGAALRLVDAVLTGAVHNG-------------VALVRPPGHHSQRAAANG--------FCVFNNVAIAARHAKQKY--GLQRILIVDWDVHHGQGIQYIFEDDPSVLYFSWHRYEHG-----------------------NFWPFLPESDADTVGRGRGQGFTVNLPWNQV----------------------------------------------GMGNADYLAAFLHVLLPLAFEFDPELVLVSAGFDSAIG----------------DPEGQMQATPECFAHLTQLLQVLAGGRICAVLE-------------------------------------------------------------------------------------------------------------------------------------CPGVYPECSDSPDP-SLDKPPTNSTCTVAEDSLSPCLDRPCHRPTPPICIAVALAVSGAALDLPPG--VLHQ---EGSALREETEAWARLHKS-------------QFQDDDLAALGKSLCLLDGILDG-QIRSAIATTTALATAATLGVLIQRCVAH--------------RGQR----------------------RILWLSIRGKE-----------------ADIWSMFHFSTPLP------QTTGGFLSFILGLVLPLAYGFQPDMVLMALGPAHGLQN--AQAAL---------LAAMLRSPVGGRILALVEE----ESILQLARTLAQVLHGETPP--------SLGPFSMASP------EEIQALMFLKAQLEPRWKLLQVAAPPP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P3E7-1", "uniprot_id": "HDA10_MOUSE", "id": "Q6P3E7-1", "name": "Polyamine deacetylase HDAC10", "aln": "---------------------------------------------------------------------------------------------------------MGTALVYHEDMTATRLLWDDPECEIECPERLTAALDGLRQRGLEER------------CLCLSACEASEEELGLVHSPEYIALVQKTQTLDKEE------------------LHALSKQYNA----VYFHPDTFHCARLAAGAALQLVDAVLTGAVHNG-------------LALVRPPGHHSQRAAANG--------FCVFNNVALAAKHAKQKY--GLQRILIVDWDVHHGQGIQYIFNDDPSVLYFSWHRYEHG-----------------------SFWPFLPESDADAVGQGQGQGFTVNLPWNQV----------------------------------------------GMGNADYLAAFLHVLLPLAFEFDPELVLVSAGFDSAIG----------------DPEGQMQATPECFAHLTQLLQVLAGGRICAVLEGGYHLESLAQSVCMMVQTLLGDPTP-PLLGLMVPCQSALESIQSVQTAQTPYWTSLQQN--------------------------------------------------------------------------VAPVLSSSTHSPEERSLRLLGESPTCAVAEDSLSPLLDQLCLRPAPPICTAVASTVPGAALCLPPG--VLHQ---EGSVLREETEAWARLHKS-------------RFQDEDLATLGKILCLLDGIMDG-QIRNAIATTTALATAATLDVLIQRCLAR--------------RAQRVLCVALGQLD---RPLDLADDGRILWLNIRGKD-----------------AAIQSMFHFSTPLP------QTTGGFLSLILGLVLPLAYGFQPDMVLMALGPAHGLQN--AQAAL---------LAAMLRSPVGGRILAVVEE----ESIRLLARSLAQALHGETPP--------SLGPFSKATP------EEIQALMFLKARLEARWKLLQVAAPPP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969S8-1", "uniprot_id": "HDA10_HUMAN", "id": "Q969S8-1", "name": "Polyamine deacetylase HDAC10", "aln": "---------------------------------------------------------------------------------------------------------MGTALVYHEDMTATRLLWDDPECEIERPERLTAALDRLRQRGLEQR------------CLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEE------------------LQALSGQFDA----IYFHPSTFHCARLAAGAGLQLVDAVLTGAVQNG-------------LALVRPPGHHGQRAAANG--------FCVFNNVAIAAAHAKQKH--GLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHG-----------------------RFWPFLRESDADAVGRGQGLGFTVNLPWNQV----------------------------------------------GMGNADYVAAFLHLLLPLAFEFDPELVLVSAGFDSAIG----------------DPEGQMQATPECFAHLTQLLQVLAGGRVCAVLEGGYHLESLAESVCMTVQTLLGDPAP-PLSGPMAPCQSALESIQSARAAQAPHWKSLQQQDV------------------------------------------------------------------------TAVPMSPSSHSPEGRPPPLLPGGPVCKAAASAPSSLLDQPCLCPAPSVRTAVALTTPDITLVLPPD--VIQQ---EASALREETEAWARPHES-------------LAREEALTALGKLLYLLDGMLDG-QVNSGIAATPASAAAATLDVAVRRGLSH--------------GAQRLLCVALGQLD---RPPDLAHDGRSLWLNIRGKE-----------------AAALSMFHVSTPLP------VMTGGFLSCILGLVLPLAYGFQPDLVLVALGPGHGLQG--PHAAL---------LAAMLRGLAGGRVLALLEE----NSTPQLAGILARVLNGEAPP--------SLGPSSVASP------EDVQALMYLRGQLEPQWKMLQCHPHLVA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QCV2-1", "uniprot_id": "HDA10_DANRE", "id": "F1QCV2-1", "name": "Polyamine deacetylase HDAC10", "aln": "-------------------------------------------------------------------------------------------------------MASGSALIFDEEMSRYKLLWTDPACEIEVPERLTVSYEALRTHGLAQR------------CKAVPVRQATEQEILLAHSEEYLEAVKQTPGMNVEE------------------LMAFSKKYND----VYFHQNIYHCAKLAAGATLQLVDSVMKREVRNG-------------MALVRPPGHHSQRSAANG--------FCVFNNVAIAALYAKKNY--NLNRILIVDWDVHHGQGIQYCFEEDPSVLYFSWHRYEHQ-----------------------SFWPNLPESDYSSVGKGKGSGFNINLPWNKV----------------------------------------------GMTNSDYLAAFFHVLLPVAYEFDPELVIVSAGFDSAIG----------------DPEGEMCALPEIFAHLTHLLMPLAAGKMCVVLEGGYNLTSLGQSVCQTVHSLLGDPTP-RISGLGTACDSALESIQNVRNVQSSYWSSFKHLAQS-----------------------------------------------------------------------ETNPKRPRLDATNGGPKESSEPASESNPKKTAQDIVWPEPLKRMPASVRTVVVP-PPGVELTLPKN--CQHSGDISESTAKEVQRIRDKHFHD-------------LTDQNILRSLGNIISVLDRMMRSDEVCNGCVVVSDLS--VSVQCALQHALTE--------------PAERVLVVYVGDGE---LPVKTN-DGKVFLVQICTKE-----------------TEDKCVNRLSLCLRE---GESLTAGFMQALLGLILPVAYEFNPALVLGIVGETAAKTG--LMTVWGH-------MTCLIQGLARGRTLTLLQG----YDKDLLELTVS-ALSGASIS--------PLGPLRALKP------EDVEMMEKQRQRLQERWGLLRCTVSES------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Z2V5-1", "uniprot_id": "HDAC6_MOUSE", "id": "Q9Z2V5-1", "name": "Protein deacetylase HDAC6", "aln": "---------MTSTGQDSS-TRQRKSRHNPQSP-------LQESSATLKRGGKKCAVPHSSPN----LAEVKKKGK--MKKLSQPAEEDLVVGLQGLDLNPETRVPVGTGLVFDEQLNDFHCLWDDS--FPESPERLHAIREQLILEGLLGR------------CVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGE------------------LRVLAETYDS----VYLHPNSYSCACLATGSVLRLVDALMGAEIRNG-------------MAVIRPPGHHAQHNLMDG--------YCMFNHLAVAARYAQKKH--RIQRVLIVDWDVHHGQGTQFIFDQDPSVLYFSIHRYEHG-----------------------RFWPHLKASNWSTIGFGQGQGYTINVPWNQT----------------------------------------------GMRDADYIAAFLHILLPVASEFQPQLVLVAAGFDALHG----------------DPKGEMAATPAGFAHLTHLLMGLAGGKLILSLEGGYNLRALAKGVSASLHTLLGDPCP-MLESCVVPCASAQTSIYCTLEALEPFWEVLERSVETQEEDEVEEAVLEEEEEEG-GWEATALPMDTWP---------------------LLQNRTGL---------VYDEKMMSHCNLWDNHHPETPQRILRIMCHLEEVGLAARCLILPARPALDSELLTCHSAEYVEHLRT--TEKMK--TRDLHREGANFDSIYICP-------------STFACAKLATGAACRLVEAVLSG-EVLNGIAVVRPPGHHAEPNAACGFCFFNSVAVAARHAQIIAGRALRILIVDWDVHHGNGTQHIFEDDPSVLYVSLHRYDRGTFFPMGDEGASSQVGRDAGIGFTVNVPWNG---PRMGDADYLAAWHRLVLPIAYEFNPELVLISAGFDAAQGD--PLGGCQVTPEGYAHLTHLLMGLAGGRIILILEGGYNLASISESMAACTHSLLGDPPPQLTLLRPPQSGALVSISEVIQVHRKYWRSLRLMKMEDKEECSSSRLVIKKLPPTASPVSAKEMTTPKGKVPEESVRKTIAALPGKESTLGQAKSKMAKAVLAQGQ--------------------------------------------------------SSEQAAKGTTLDLATSKETVGGATTDLWASAAAPENFPNQTTS-VEALGETEP--TPPASHTNKQTTGASPLQGVTAQQSLQ--LGVLSTLELSREAEEAHDS----EEGLLGEAAGGQDMNSLMLTQGFGDFNTQDVFYAVTPLSWCPHLMAVCPIPAAGLDVSQPCKTCGTVQENWVCLTCYQVYCSRYVNAHMVCHHEASEHPLVLSCVDLSTWCYVCQAYVHHEDLQDVKNAAHQNKFGEDMPHSH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GM68-1", "uniprot_id": "HDAC6_RAT", "id": "A0A8I6GM68-1", "name": "Protein deacetylase HDAC6", "aln": "---------MTSTGQDSS-TRQRKSRHNPQSP-------LQDSSATLKRGGKKGAVPHSSPN----LAEVKKKGK--MKKLSQPAEEDLIVGLQGLDLNSETRVPVGTGLVFDEQLNDFHCLWDDS--FPENPERLHAIKEQLILEGLLGR------------CVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGE------------------LRVLAGTYDS----VYLHPNSYSCACLATGSVLRLVDAVMGAEIRNG-------------MAVIRPPGHHAQRSLMDG--------YCMFNHLAVAARYAQKKH--RIQRILIVDWDVHHGQGTQFIFDQDPSVLYFSIHRYEHG-----------------------RFWPHLKASNWSTTGFGQGQGYTINVPWNQVSFCSHKLSLACFPRGSREMTDYYIAFLC---------------LQVGMRDADYIAAFLHILLPVAFEFQPQLVLVAAGFDALHG----------------DPKGEMSATPAGFAHLTHFLMGLAGGKLILSLEGGYNLHALAKGVSGSLHTLLGDPCP-MLESPVAPCASAQTSISCTLEALEPFWEVLERSVEPQDEDEVEGDMLEDEEEEG-HWEATALPMDTWP---------------------LLQNRTGL---------VYDERMMSHCNLWDNHHPETPQRILRIMCHLEEVGLAARCLILPARPALDSELLTCHSAEYVERLRA--TEKMK--TRDLHREGANFESIYICP-------------STFACAQLATGAACRLVEAVLSG-EVLNGIAIVRPPGHHAEPDAACGFCFFNSVAVAARHAQVIAGRALRILIVDWDVHHGNGTQHIFEEDPSVLYVSLHRYDRGTFFPMGDEGASSQVGRAAGTGFTVNVPWNG---PRMGDADYLATWHRLVLPIAYEFNPELVLISAGFDAAQGD--PLGGCQVTPEGYAHLTHLLMGLAGGRIILILEGGYNLTSISESMAACTHSLLGDPPPQLTSLRPPQSGALASISEVIQVHRKYWRSLRLMKMEDKEERSSSRLVIKKLPQSASPVSAKGMTTPKGKVLEAGMRKPTAALPTKESTLGQAKAKTAKALLAQGQ--------------------------------------------------------SSEQAAKGTTLDLATSKDTVGGATTDQCASVAATENSANQTTSGEEASGETESFGTSPSSNASKQTTGASPLHGAAAQQSPE--LGLSSTLELSSEAQEVQES----EEGLLGEAAGGQDMNSLMLTQGFGDFNTQDVFYAVTPLSWCPHLMAVCPIPAAGLDVSQPCKTCGSVQENWVCLTCYQVYCSRYVNAHMVCHHEASEHPLVLSCVDLSTWCYLCQAYVHHEDLQDVKNAAHQNKFGEGMPHLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBN7-1", "uniprot_id": "HDAC6_HUMAN", "id": "Q9UBN7-1", "name": "Protein deacetylase HDAC6", "aln": "---------MTSTGQDSTTTRQRRSRQNPQSP-------PQDSSVTSKRNIKKGAVPRSIPN----LAEVKKKGK--MKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDS--FPEGPERLHAIKEQLIQEGLLDR------------CVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGE------------------LRVLADTYDS----VYLHPNSYSCACLASGSVLRLVDAVLGAEIRNG-------------MAIIRPPGHHAQHSLMDG--------YCMFNHVAVAARYAQQKH--RIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQG-----------------------RFWPHLKASNWSTTGFGQGQGYTINVPWNQV----------------------------------------------GMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQG----------------DPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCP-MLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEG-PWEPPVLPILTWP---------------------VLQSRTGL---------VYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRA--TEKMK--TRELHRESSNFDSIYICP-------------STFACAQLATGAACRLVEAVLSG-EVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNG---PRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGD--PLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PJN5-1", "uniprot_id": "M9PJN5_DROME", "id": "M9PJN5-1", "name": "Protein deacetylase HDAC6", "aln": "--MSPPIVTRRSAQQAKIQTRAMASKSKTGTTGAATAAGGTGSSSGSISGGFNAADPRKSNKPNAALLEAKRRARNNMLKNQGCGSQESVTDIFQNAVNSKSLVRKPTALIYDESMSQHCCLWDKE--HYECPERFTRVLERCRELNLTER------------CLELPSRSATKDEILRLHTEEHFERLKETSGIRDDER-----------------MEELSSRYDS----IYIHPSTFELSLLASGSTIELVDHLVAGKAQNG-------------MAIIRPPGHHAMKAEYNG--------YCFFNNVALATQHALDVH--KLQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHG-----------------------SFWPHLHESDYHAIGSGAGTGYNFNVPLNAT----------------------------------------------GMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALG----------------CPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQTYDCVELQDRDKEEDLHTVLRHWIGGPPPMDRYPTRDTAIPLPPEKLTSNAARLQVLRAETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRR--LLGRE--PKELHDAAGIYNSVYLHP-------------RTFDCATLAAGLVLQAVDSVLRG-ESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDFG-LERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNK---KGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGD--PLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVP------TPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEFVGRRLPR--DPVVGE---NNNEDFLTASLRHLNISNDDATAAAGGLAGDRPDCGDERPS--------------------------------------------------------GSKPKVKVKTLSDYLAENKEALEQSEMFAVYPLKTCPHLRLLRPEEAPRSLDSGAECSVCGSTGENWVCLSCRHVACGRYVNAHMEQHSVEEQHPLAMSTADLS-------VWCYACSAYVDHPRLYAYLNPLHEDKFQEPMAWTHGCAWREDGC--YATGPDGRDEDDDDDNGAGSSICLRLERNNX-----PLAIRVLDALTDYLCALCPPLR-----HLIHFLAEHLWPLLERIYLNLLHYFLAH--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53973-1", "uniprot_id": "HDA1_YEAST", "id": "P53973-1", "name": "Histone deacetylase HDA1", "aln": "----------------------------------------------MDSVMVKKEVLENPDHDLKRKLEENKEEENSLSTTSKSKRQVIVPVCMPKIHYSPLKTGLCYDVRMRYHAKIFTSYFEYIDPHPEDPRRIYRIYKILAENGLINDPTLSGVDDLGDLMLKIPVRAATSEEILEVHTKEHLEFIESTEKMSREE------------------LLKETEKGDS----VYFNNDSYASARLPCGGAIEACKAVVEGRVKNS-------------LAVVRPPGHHAEPQAAGG--------FCLFSNVAVAAKNILKNYPESVRRIMILDWDIHHGNGTQKSFYQDDQVLYVSLHRFEMG-----------------------KYYPGTIQGQYDQTGEGKGEGFNCNITWPVG----------------------------------------------GVGDAEYMWAFEQVVMPMGREFKPDLVIISSGFDAADG----------------DTIGQCHVTPSCYGHMTHMLKSLARGNLCVVLEGGYNLDAIARSALSVAKVLIGEPPDELPDPLSDPKPEVIEMIDKVIRLQSKYWNCFRRR-----------------------------------------------------------------------------HANSGCNFNEPINDSIISKNFPLQKAIRQQ--QQHYLSDEFNFVTLPLVSMDLPDNTVLCTPN--ISESNTIIIVVHDTSDIWAKRNVIS-------------GTID--LSSSVIIDNSLDFIKWGLDRKYGIIDVNIPLTLFEPDNYSGMITSQ-----------------------------------------EVLIYLWDN-------------------------YIKYFPSV---AKIAFIGIGDSYSGIVHLLGHRDTRAVTKTVINFLGDKQ-----------------LKPLVPLVDETLSEWYFKN---SLIFSNNSHQCWKENESRKPR-------KKFGRVLRCDT------DGLNNIIEERFEEATDFILDSFEEWSDEE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P56524-1", "uniprot_id": "HDAC4_HUMAN", "id": "P56524-1", "name": "Histone deacetylase 4", "aln": "MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLPVAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLAMKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVLNKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFPLRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGPSSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPATGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLLEQPPAQAPLVTGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQALLDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQALLLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQ-----------------------EPPTKPRFTTGLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAVGCVVELVFKVATG-ELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQR-LSVSKILIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFP--GSGAPDEVGTGPGVGFNVNMAFTGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGYLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDP-------LPEKVLQQRP-------NANAVRSMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDEEPMEEEPPL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . : :. : . . . : : : :* . : . :. . : .. *: : * . .. . :: . : :.*.. : . : .: :* . * : . * :. : : : : : . : .: : . .. . * .: * . : . : : : . : . . . . : : .. :: :. :. . : : .: . . : ", "identical_positions": 9, "similar_positions": 95, "identity": "0.63%" }, { "cls_id": "homologset.agr.SGD:S000004967", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V660-1", "uniprot_id": "G3V660_RAT", "id": "G3V660-1", "name": "28S rRNA (cytosine-C(5))-methyltransferase", "aln": "-----------MGLYATAAAVLAGVESRQGSLKGLVYSSNFQNLKQLYALVCETQRYSAVLDAVIASAGLLRAEKKLR------PHLAKVLVYELLLGK--GFRGGGGRWKALLGRHQARLKAELARLKVHRGVSRNEDLLQE--RPGQAHQVPRFVRVNTLKTCPEDAIDYFKRQGFSYQGR------ASSLEDLRTLKGQHFLLDPLLPELLVFPAQTD--LHEHPLYRAGHLILQDKASCLPAMLLSPPPGSHVIDACAAPGNKTSYIAALLK------NQGKIFAFDQDAKRLAAMATLLARAGVSCCEVAEKDFLTVSPSDQRYGQVQYILLDPSCSGSGMLSRQLEEHGEGTPSK-----------------------ERLQALAGFQQRALCHAL-RFPSLQRLVYSTCSLCQEENEDVVQEALQ---QNSGTFRLAP---VLPTWPHRG-LSTFPGS-------------EHCLRASPETTLTGGFFIAVFERAEVVPSPAPQTSAVVPEPLSKAPKRKRRR----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K4F6-1", "uniprot_id": "NSUN5_MOUSE", "id": "Q8K4F6-1", "name": "28S rRNA (cytosine-C(5))-methyltransferase", "aln": "-----------MGLYAAAAAVLAGVESRQGSLKGLVYSSNFQNLKQLYALVCETQRYSAVLDAVIASAGLLRAEKKLR------PHLAKVLVYELLLGK--GFRGGGGRWKALLGRHQARLKAELARLKVHRGVSRNEDLLQESSRPGQAYQVPRFVRVNTLKTRPEDAIDYFKRQGFSYQGR------ASSLEDLRALKGQHFLLDPLLPELLVFPAQTD--LHEHPLYRAGHLILQDKASCLPAMLLSPPPGSHVIDACAAPGNKTSYIAALLK------NQGKIFAFDQDAKRLAAMATLVARAGVSCCELAEKDFLTVSPSDQRYSQVQYILLDPSCSGSGMLSRQLEEHGEGTPSK-----------------------ERLQALAGFQQRALCHAL-RFPSLQRLVYSTCSLCQEENEDVVQEALQ---HNSGTFRLAP---VLPTWPHRG-LSTFPGS-------------EHCLRASPETTLTGGFFIAVFERAEVVPTPAPQTDAMDPEPLSQVPKRKRRRKAAVGASMQPST----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96P11-1", "uniprot_id": "NSUN5_HUMAN", "id": "Q96P11-1", "name": "28S rRNA (cytosine-C(5))-methyltransferase", "aln": "-----------MGLYAAAAGVLAGVESRQGSIKGLVYSSNFQNVKQLYALVCETQRYSAVLDAVIASAGLLRAEKKLR------PHLAKVLVYELLLGK--GFRGGGGRWKALLGRHQARLKAELARLKVHRGVSRNEDLLEVGSRPGPASQLPRFVRVNTLKTCSDDVVDYFKRQGFSYQGR------ASSLDDLRALKGKHFLLDPLMPELLVFPAQTD--LHEHPLYRAGHLILQDRASCLPAMLLDPPPGSHVIDACAAPGNKTSHLAALLK------NQGKIFAFDLDAKRLASMATLLARAGVSCCELAEEDFLAVSPSDPRYHEVHYILLDPSCSGSGMPSRQLEEPGAGTPSP-----------------------VRLHALAGFQQRALCHAL-TFPSLQRLVYSTCSLCQEENEDVVRDALQ---QNPGAFRLAP---ALPAWPHRG-LSTFPGA-------------EHCLRASPETTLSSGFFVAVIERVEVPR----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63ZY6-1", "uniprot_id": "NSN5C_HUMAN", "id": "Q63ZY6-1", "name": "Putative methyltransferase NSUN5C", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPELLVFPAQTD--LHEHPLYRAGHLILQDRASCLPAMLLDPRQAPMSWMPVPPQAIKTSHLAALLK------NQGKIFAFDLDARRLASMATLLAWAGVSCCELAEEDFLAVSPLDPRYREVHYVLLDPSCSGSGMPSRQLEEPGAGTPSP-----------------------VRLHALAGFQQRALCHAL-TFPSLQRLVYSMCSLCQEENEDMVQDALQ---QNPGAFRLAP---ALPARPHRG-LSTFPGA-------------EHCLRASPKTTLSGGFFVAVIERVEMPTSASQAKASAPERTPSPAPKRKKRAKSCSRCLHTALHIAEAPGSLLPGGKGRCLSSPWKTLGPHRRQQFAF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3KNT7-1", "uniprot_id": "NSN5B_HUMAN", "id": "Q3KNT7-1", "name": "Putative NOL1/NOP2/Sun domain family member 5B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATLLAWVGVSCCELAEEDFLAVSPLDPRYREVHYVLLDPSCSGSGMPSRQLEDPGAGTPSP-----------------------VRLHALAGFQQRALCHAL-TFPSLQRLVYSMCSLCQEENEDMVPDALQ---QNPGAFRLAP---ALPARPHRG-LSTFPGA-------------EHCLRASPKTTLSGGFFVAVIERVEMPT----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BD27-1", "uniprot_id": "A0A8M3BD27_DANRE", "id": "A0A8M3BD27-1", "name": "", "aln": "-----------MALYLKAAEILEKVEQKRGAVKTLVYDSKFPNIKQLFALVCETQKYSSVLQEIINSTKLLK-ETKLR------IHLAKVLVYDLLIGH--GVKCGG-AWKTTMLKHRARLQAALARIKIKRKVSRNQDLLPSSIQQTQNDVIPRYVRVNTLKTSLEDVIDYLKREGFSYQGT------PGRLEDLDRLSGKMFLCDLHLKDLLVFSGKTD--FHDHFLYKAGHIILQGKASCLPAFLLNPPVGSHVIDACAAPGNKTSHLAAIMK------NKGKLFAFDLDAKRLSTMSTLLLRAGVTCHKLANQDFLKVDPQNSEYKEVKYILLDPSCSGSGMVCLRDELP--ETQED-----------------------GRLQALAAFQLHCLNHAL-QFPQLERIVYSTCSIHSQENEEVVTACLQ---RNPG-FRLVH---LLPDWPERG-HEPLT----------------QCLRASTAKTRTHGFFVAMLERRPAQSDKETPPLNTPLSSASQEKQDKPQSNPSDEEQENMETSNEQPANPSSKKKRK------RNRKKHKKQES--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDZ4-1", "uniprot_id": "NSUN5_DROME", "id": "Q9VDZ4-1", "name": "28S rRNA (cytosine-C(5))-methyltransferase", "aln": "-MSKKPHSIKVPTQYRATAKILKAALEQQKCIKTLIFAEKHARTRSLHTVLKKFSENRVALEKAIEETGLLRDNPSFD------PSLAKILVTELLFGR--KELNGESKPVQTVRSYKDRLLNSIRDFGVQR-----------------KEPNPRYVRINTNLYSLAEALDYLHKSDWRRKELPADASYADFLTAIKSLAENEFMTDLHVEGVLIFPAKWSNYWVRHPLVHSKRFILQNKATCLAAELLAPPSGATVLDMCAAPGMKTVHICNVMQ------NKGCIYSVEQDHVRYNTLCEITKDAGCDIVKPILGDALNLTP--ERFPDVEYILVDPSCSGSGMQNR--MTVCDEPKED-----------------------KRLQKLQGLQIKILSHAMGAFPNVKRIAYCTCSLWKEENEQVVQRCLQ---LNPSFKLLSCKKALRNKWHNVG-DKDYPNIG------------KNVLYCQPDSDLTDGIFLALFEKRREGEKD--------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53972-1", "uniprot_id": "RCM1_YEAST", "id": "P53972-1", "name": "25S rRNA (cytosine(2278)-C(5))-methyltransferase", "aln": "MNFYRDATWVLEDIEKEAAKERISGSMQTLVLKSCKRYKLKSNPKHIYAVLDSCWKYKPYLEKVMKKAHILEDIPKKKGKPLFSRLTLLLLCHDLLLSKQKRIQMGKHPIKDYVLKFKSPLHSEMVKLKLKLKVRELSELVLS-EDISNDLPPVRWIRINPLKCHPNGETEPVLAELRKKFTLK--------VDKWSELVPGSIYYDEFIPNLFGIHPSDK--ITAHELYKHGKIIIQDRASCFPAHILNPGPSDIVIDSCSAPGNKTTHTASYIYPEPPKDNNTRIYAFEKDPERAKVLQKMIKIAGCSPNISVNVGDFTKLATPEKYKDVTCFIVDPSCSGSGIFGRKFFDSFNRRKIDDKDDDGGIVPDEQEEFIAKEELQTRLAKLSSFQFQMVKHAM-SFPAAKKIVYSTCSIHAEENERVVIDLLLDKSVREWGWKVAPKREVIPSWPRRGKVEEFEEVFRDGVTYDPQQLAEGCIRALPKSDGGIGFFAVCFERD--------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .* . : . .: :* .::********: ** * .:* : : **: ** :::.*. **: :*** :* * . : . * . : . . . *:* . :*: ", "identical_positions": 30, "similar_positions": 38, "identity": "5.21%" }, { "cls_id": "homologset.agr.SGD:S000004968", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AE50-1", "uniprot_id": "D4AE50_RAT", "id": "D4AE50-1", "name": "Transcriptional repressor NF-X1", "aln": "----MAEAPPVSGTFKFNTDAAEFIPQERKNSGLNCGTQRRLDSNR--------IGRRNYSSSPPCHLPRHIPYDDVSAVHQHGYA-SGSKP---KSPQGFFQSS--NKSLKNHGLQNQPWQKLRNEKHQNRIKKAQGLTEQTSDTSSLESVARSESGTNPREHSPSESEK---------------EVVIADPRGAKPKKATQLTYNYGRGPKAKGRLRSEWGNRMSPKSED---ENARPVAISHS---DSSEASCRKPVVDPCVCRRSEQRRYPQKRPPWEVEGARPRPGRNPPKQESQRHINAGPKNNMPPLPKDNLRERPTKSACDTGNLAVVTKSSRRVDQEKNAGRRQDPQVLSPFPRGKQNHMLKNVETHTGSLIEQLTTEKYECMVCCELVQVTAPVWSCQSCFHVFHLNCIKKWARSPASHADGQSGWRCPACQNVSAHVPSTYTCFCGKVKNPEWSRNEIPHSCGEVCRKKQPGQDCPHSCNLLCHPGPCP-PCPAFTTKTCECGRTRHTVRCGQPVSVHCSNVCENILNCGQHRCAELCHAGQCQPCRIILNQVCYCGSTSRDVLCGTDVGKSDGFGDFSCLKICGKDLKCGSHTCSQVCHPQPCQPCPRLPHLVRYCPCGQTPLSQLLEHGSNGRKTCMDPVPSCGKVCGKPLS----CGSSDFIHTCEKLCHEGDCGPCSRTSVISCRCSFRTKELPCTSLKSEDATFMCDKRCNKKRLCGRHKCNEICCVD--KEHKCPLICGRKLRCGLHRCEEPCH-RGNCQTCWQASFDELTCHCGASVIYPPVPCGTRPPECTQTCARIHECDHPVYHSCHSEEKCPPCTFLTQKWCMGK---HELRSNIPCHLVDISCGLPCSAMLPCGMHKCQRLCHKGECLVD-EACKQPCTTPRADCGHPCMAPCHPSLPCPVTACKAKVELQCECGRRKEMVICSEASGTYQRIAAISMASKITDMQLGDSVEISKFITKKEVQQARLQCDEECAALERKKRLAEAFDITDDSDPFNVRSSASKFSDSLKDDARKDFKFVSDIEKEMEALVEAVNKGKSNKKSYCFPPMNRDHRRIIHDLAQVYGLESVSYDSEPKRNVVVTAIRGKSICPPTTLTSVIERETQTRPPPPIPHHRHQADKNPGSSNLQKIVKEPVIDYFDVQD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AY10-1", "uniprot_id": "NFX1_MOUSE", "id": "B1AY10-1", "name": "Transcriptional repressor NF-X1", "aln": "----MAEAPPVSGTFKFNTDAAEFIPQERKTSGLNCGTQRRLDSSR--------IGRRNYSSSPPCHLPRHIPYEDISAVHQHSYA-SGSKP---KSPQGFFQSS--NKSLKNHGLQNQPWQKARNEKHQNRNKKAQGLSEQTSDTSSLESVARSESGTNPREHSPSESEK---------------EVVIADPRGAKPKKAAQLTYNYGRGPKAKGRLRSEWGNRMSPKSED---ENTRPVAISHT---DSSDASCRKPVVDPCVCRRNEQRRYPQKRPPWEVEGARPRPGRNPPKQESQRHINAGPKTNMSPIPKDNLRERPTKSACDTGNLAVVSKSSRRVNQEKTAVRRQDPQVLSPFPRGKQNHMLKNVETHTGSLIEQLTTEKYECMVCCELVQVTAPVWSCQSCFHVFHLNCIKKWARSPASHADGQSGWRCPACQNVSAHVPNTYTCFCGKVKNPEWSRNEIPHSCGEVCRKKQPGQDCPHSCNLLCHPGPCP-PCPAFTTKTCECGRTRHTVRCGQPVSVHCSNACENILNCGQHHCAELCHGGQCQPCRIILNQVCYCGSTSRDVLCGTDVGKSDGFGDFSCLKICGKDLKCGSHTCSQVCHPQPCQPCPRLPHLVRYCPCGQTPLSQLLEHGSNARKTCMDPVPSCGKVCGKPLA----CGSSDFIHTCEKLCHEGDCGPCSRTSVISCRCSFRTKELPCTSLKSEDATFMCDKRCNKKRLCGRHKCNEICCVD--KEHKCPLICGRKLRCGLHRCEEPCH-RGNCQTCWQASFDELTCHCGASVIYPPVPCGTRPPECTQTCARIHECDHPVYHSCHSEEKCPPCTFLTQKWCMGK---HELRSNIPCHLVDISCGLPCSAMLPCGMHKCQRLCHKGECLVD-EACKQPCTTPRGDCGHPCMAPCHPSLPCPVTACKAKVELQCECGRRKEMVICSEASGTYQRIVAISMASKITDMQLGDSVEISKLITKKEVQQARLQCDEECAALERRKRLAEAFDITDDSDPFNVRSSASKFSDSLKDDARKDLKFVSDVEKEMETLVEAVNKGKNNKKSHCFPPMNRDHRRIIHDLAQVYGLESISYDSEPKRNVVVTAVRGKSVCPPTTLTSVIERETQTRPPPPIPHHRHQADKAPGSSTLQKIVKEAVIDYFDVQD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12986-1", "uniprot_id": "NFX1_HUMAN", "id": "Q12986-1", "name": "Transcriptional repressor NF-X1", "aln": "----MAEAPPVSGTFKFNTDAAEFIPQEKKNSGLNCGTQRRLDSNR--------IGRRNYSSPPPCHLSRQVPYDEISAVHQHSYHPSGSKP---KSQQTSFQSSPCNKSPKSHGLQNQPWQKLRNEKHHIRVKKAQSLAEQTSDTAGLESSTRSESGTDLREHSPSESEK---------------EVVGADPRGAKPKKATQFVYSYGRGPKVKGKLKCEWSNRTTPKPEDAGPESTKPVGVFHP---DSSEASSRKGVLDGYGARRNEQRRYPQKRPPWEVEGARPRPGRNPPKQEGHRHTNAGHRNNMGPIPKDDLNERPAKSTCDSENLAVINKSSRRVDQEKCTVRRQDPQVVSPFSRGKQNHVLKNVETHTGSLIEQLTTEKYECMVCCELVRVTAPVWSCQSCYHVFHLNCIKKWARSPASQADGQSGWRCPACQNVSAHVPNTYTCFCGKVKNPEWSRNEIPHSCGEVCRKKQPGQDCPHSCNLLCHPGPCP-PCPAFMTKTCECGRTRHTVRCGQAVSVHCSNPCENILNCGQHQCAELCHGGQCQPCQIILNQVCYCGSTSRDVLCGTDVGKSDGFGDFSCLKICGKDLKCGNHTCSQVCHPQPCQQCPRLPQLVRCCPCGQTPLSQLLELGSSSRKTCMDPVPSCGKVCGKPLP----CGSLDFIHTCEKLCHEGDCGPCSRTSVISCRCSFRTKELPCTSLKSEDATFMCDKRCNKKRLCGRHKCNEICCVD--KEHKCPLICGRKLRCGLHRCEEPCH-RGNCQTCWQASFDELTCHCGASVIYPPVPCGTRPPECTQTCARVHECDHPVYHSCHSEEKCPPCTFLTQKWCMGK---HEFRSNIPCHLVDISCGLPCSATLPCGMHKCQRLCHKGECLVD-EPCKQPCTTPRADCGHPCMAPCHTSSPCPVTACKAKVELQCECGRRKEMVICSEASSTYQRIAAISMASKITDMQLGGSVEISKLITKKEVHQARLECDEECSALERKKRLAEAFHISEDSDPFNIRSSGSKFSDSLKEDARKDLKFVSDVEKEMETLVEAVNKGKNSKKSHSFPPMNRDHRRIIHDLAQVYGLESVSYDSEPKRNVVVTAIRGKSVCPPTTLTGVLEREMQARPPPPIPHHRHQSDKNPGSSNLQKITKEPIIDYFDVQD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40798-1", "uniprot_id": "STC_DROME", "id": "P40798-1", "name": "Protein shuttle craft", "aln": "MAEYWQQLTNGAGEAGPGNESSAMADCNGGHESAAVGGSCNRHSNNNYVNFNQFIMQHNLGGGAPSNATSTMQHPVGSSYTNFSLGGGGGAFGLNPPVASASTSHFANVSHQSPNFYSQAMIPTYQNGDGIARVTVTSSYGSVNPSNSNFSSFYTPFGNNPFDFSASKLQASAPEFVPNFAKLSLEETPAAATTNGNSTASLETAINETRPRTLRAQEPAERGANNQCSNHNYERERERERDRDRDRERDRDRDRDRDRDRDRDRDRDSRPGNTRQQRRSDYRDDREDRYERSDRRRPQKQQRYDNHRSNKRRDDWNRNRDRINGFPRAVDDLDTSNESAHPSPEKQSQLQQISPRRGPPLPPADNEKLSQ-----REKLVRDIEQRRLECLVCVEAIKSHQPTWSCRNCYHMLHLKCTITWASS----SKSEVGWRCPACQNVLQDLPRDYLCFCGKLKNPPVSRTELAHSCGEVCCRIEG---CSHACTLLCHPGPCP-PCQANVVRSCGCGRSTKTMQCAMKEEVLCGEICDKLLNCGEHRCQAECHSGKCAACSEQVVQQCHCGKQERKVPCTRESQDKR---TYSCKDSCGQPLPCGHHKCKDSCHAGSCRPCKLSPEQITSCPCGKMPVP------AGQRSSCLDPIPTCEGICSRTLR----CGKPAHPHQCGSKCHLGQCPPCPKQTGVKCRCGHMDQMIKCRQLCNRADDARCKRRCTKKRSCGKHKCNVECCID--IDHDCPLPCNRTLSCGKHKCDQPCH-RGNCPPCYRSSFEELYCECGAEVIYPPVPCGTKKPICKLPCSRIHPCDHPPQHNCHSGPTCPPCMIFTTKLCHGN---HELRKTIPCSQPNFSCGMACGKPLPCGGHKCIKPCHEGPCQSAGEICRQSCTKPRPTCGHKCAAACHEG-ACPETPCKELVEVQCECGNRKQNRSCQELAREHSRIATIQLASSMAEMSRGNYMELSEILAPAKKSNKTLDCNDECRLLERNRRLAAALSSGNSD---TKQKCLTKYSEFVRGFAKKNPALTKSVYETLTDLVKLAKESKQRSRSHSFPTMNREKRQLVHELCEVFGIESVSYDKEPNRNVVATAHKDRCWFPATSIMEVLARESGQRRVPVPSNNAWGLKK-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53971-1", "uniprot_id": "FAP1_YEAST", "id": "P53971-1", "name": "FKBP12-associated protein 1", "aln": "-----------------------------MTEHESLGLEQNQDGGD------------------------TYRHHNLSDGCISSVEDANEQP-----------SSYEEESDDDMQYYERAIQEISSGDSYVCMICTVEMDYTCQMFACKRCYRVFDYG-CIREWALKSTEK-----------------------TVDRIWKCPNCYYVSKRVPVKNRPTCWCGKVVNPDPNP----------LDPN----SCGQTCNASTCMHGCSKICHLGPHPECTRMVEIMCHCGKHSKSIFCYQSKVMKKNFNCQEVCGLPLS-CSIHTCKKKCHPGLCGPCPEMIISKDSPKKQIKCYCGNHTRANIKCSETKFPK-----SGKSSKDENGNRWIGVFACADNRVVD--YSCR--KHSFIESCISPPTIN--------GEKACPFLPSSLKTCPCGRTALEELTK-PRKHCDDPIPTCDSRCG--KPLKCGKHSCPFTCHDKACMEPCLQIDSVKCACEQSTFSVPCGFQGRPRCNIKCESLMSCRRHRCTDRCCSGRPSAIRRKKNLFRTQDLLDESLVEAK----------HICLKPCNLTLSCGIHKCQRKCHPGKCPPCLESDSNDLVCPCGNTVVP--------APVRCGTKLPTCNHPCIKVVRGESTCGHKPMPHTCHSLDVS--CPPCTETVFKPCKCGKKTKVR----TVCFQTDVSCGIKCGIPLSYCYHTCQKTCHLPGNCQKVCKQTCGQKRLNCNHECPKPCHGKTECPDLPCATLVKIYCKCGR--IKKSVTCGAKSDRVSVTESSVLDCNEECEALKRLKELKEAFGIKEETNNFTSNELDALKKLVSVATTFEELQLPFTEAALSVYSKQERWCSQIEAILN-------KLMDDKTRSSLHFKPMRPPQRHFIRELAKAYGLYSESQDREPMRSVFIKKEDNG-------ASNKPVLSLAEAYPLYESFKQLQKERKAQEFQARTTAKLIN---------------FEVQDTEPKVEVAKKNGFLVQNLVAGNTAEDLRRFFEPHLKHTLVVN-PQYLILDDGKTALVYPENYETASVNTERDMELLVGHFDFMAKEAFLADSISLCSTEEELERRLDTPVIQEDSPVMDNNT---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . . ... : * . .. * : * .. .:. . . . . * : : .. : . : : : . . . . . : . : : :. : : . : : . : : . . .: :. : . .: .: :.. : :**: * : .* : . ** . * .: * * : :*.. * : *:* : ** .* ** .* * :: :: *. *. *:.::.* .*:* * .*: . . ...: . * . *. * ** *.*. **. * * ****: :. * :*:* * : : ** * * . * **.. *:*. : * :* *.*: * : :: * *.:. *.* :*** : :* ::: :: *.** * .*.**:: . . : : *:. : . : . . . ::. :. . :. . * : * : . . . : : .*. *: **. . :. . : : : : . : : . . :. .* . : : .. . : : :.: : . . : :: : ::: . . . * * . . : . :: . . * .. .: ", "identical_positions": 92, "similar_positions": 229, "identity": "7.9%" }, { "cls_id": "homologset.agr.SGD:S000004969", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M2F8-1", "uniprot_id": "A0ABK0M2F8_RAT", "id": "A0ABK0M2F8-1", "name": "", "aln": "------------------------------------MTKKTATYCYSLIQH-----LMDLTKVTNSITHKETHKETRDNDDDKQVVAEIMARSFIPTLITTVSWEGFHFAG--------HEIQITEGKD-----SYGAFVWPSALVLCYFLET----HAKQYNMVD----KNVIEIGAGTGLVSIVASLL-------GARVIATDLPE--LLGNLQYNISKNTKTKCKHLPQVKELSWGVALDRNFPRSS-----NNFDYILAADVVYAHPFLEELLMTFDHLCRET------TIILWAMRFRLEK-----ENKFVDKFKELFDLEEI------SSFPSLNIKLYKAMKKNWRRA------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CDZ2-1", "uniprot_id": "MT21E_MOUSE", "id": "Q8CDZ2-1", "name": "Protein-lysine methyltransferase METTL21E", "aln": "---------------------------------------------------------MDLT-VT-HITHKETYKEPRDDDDDKQVVAEIMARSFIPTLITTIPWEGFHFAG--------HEIQITEGKD-----CYGAFVWPSALVLCYFLET----HAKQYNMVD----KNVIEIGAGTGLVSIVASLL-------GARVIATDLPE--LLGNLQYNISRNTKMKCKHLPQVKELSWGVALDRNFPRSS-----NNFDYILAADVVYAHPFLEELLMTFDHLCKET------TIILWAMRFRLEK-----ENKFVDKFKELFDLEEI------SSFPSLNIKLYKAMKKNRRSA------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NDL7-1", "uniprot_id": "MT21E_HUMAN", "id": "A6NDL7-1", "name": "Methyltransferase-like protein 21E", "aln": "-----------------------------------------------------------------------------------------MARCFIPTLITTTSWESFHFIG--------HEIRITEAMD-----CYGAVVWPSALVLCYFLET----NAKQYNMVD----KNVIEIGAGTGLVSIVASLL-------GAHVTATDLPE--LLGNLQYNISRNTKMKSKHLPQVKELSWGVALDTNFPRSS-----NNFDYILAADVVYAHPFLEELLITFDHLCKET------TIILWAMKFRLEK-----ENKFVDRFKELFDLEEI------SSFPSLNIKLYKAVKKNRRSV------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N076-1", "uniprot_id": "A0A8M1N076_DANRE", "id": "A0A8M1N076-1", "name": "", "aln": "---------------------------------------------------------------------MDQDQHDEDVSADAELAAAIMKRHFRPSLIKTEAWEGYEFAD--------KEIKITESTD-----CYGAVLWPSAMVLCHFLDS----HRDQYNLLD----KKIIELGAGTGLVTIVTSLL-------GAQVTSTDLPD--VLANLRHNVNRNTRGRCRHEPQVTELIWGQQLEERFPRYT-----CQYDYILAADVVYGHPYLQELLETFIHLCSDH------TVILWAMRFRLDP-----ENRFVHTFQEHFHLEEL------YDLPSLSIKLYRAHKR-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZJG1-1", "uniprot_id": "D3ZJG1_RAT", "id": "D3ZJG1-1", "name": "Protein-lysine methyltransferase METTL21C", "aln": "------------------------------------MDQHLHTAQQPLRLG----------------TPQEDVFAGPSVESDMIESSLHSIQKFVPTDYASYTQEHYHFAG--------KKIIIQESIE-----NYGTVVWPGATALCQYLED----HTEELNLED----AKILEIGAGPGLVSIVSSLL-------GAQVTATDLPD--VLGNLQYNISKNTLECTAHLPEVKELVWGEDLDQKFPKSS-----FYYDYVLASDVVYHHYFLDKLLATMVYLSQPG------TVVLWANKFRFST-----DYEFLDKFKQAFDTTLL------AEHSESSVKLFKGILKWD---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLU2-1", "uniprot_id": "MT21C_MOUSE", "id": "Q8BLU2-1", "name": "Protein-lysine methyltransferase METTL21C", "aln": "------------------------------------MDQHLHIAQQPLLSG----------------TPQEDGFAGPSVEFDRIESSLRSIQKFVPTDYASYTQEHYQFAG--------KKIIIQESIE-----NYGTVVWPGATALCQYLED----HTEELNLQD----AKILEIGAGAGLVSIVSSLL-------GAQVTATDLPD--VLGNLQYNILKNTLECTAHLPEVRELVWGEDLEQSFPKST-----CCYDYVLASDVVYHHYFLDKLLATMVYLSQPG------TVVLWANKFRFSA-----DYEFLGKFKQAFDTTLL------AEYSESSVKLFKGILKWE---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VZV1-1", "uniprot_id": "MT21C_HUMAN", "id": "Q5VZV1-1", "name": "Protein-lysine methyltransferase METTL21C", "aln": "------------------------------------MDVCLSSAQQPGRRGEGLSSPGGWLEAEKKGAPQKDSTGGVLEESNKIEPSLHSLQKFVPTDYASYTQEHYRFAG--------KEIVIQESIE-----SYGAVVWPGAMALCQYLEE----HAEELNFQD----AKILEIGAGPGLVSIVASIL-------GAQVTATDLPD--VLGNLQYNLLKNTLQCTAHLPEVKELVWGEDLDKNFPKSA-----FYYDYVLASDVVYHHYFLDKLLTTMVYLSQPG------TVLLWANKFRFST-----DYEFLDKFKQVFDTTLL------AEYPESSVKLFKGILKWD---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A8Z5-1", "uniprot_id": "D4A8Z5_RAT", "id": "D4A8Z5-1", "name": "Protein N-lysine methyltransferase METTL21A", "aln": "--------------------------------------------------------------------------MALVPYEESMSIG---------LQKLHKPLATFSFAN--------HTIQIRQDWG---RLGVAAVVWDAAIVLSTYLE------MGAVELRG----CSAVELGAGTGLVGIVAALL-------GAHVTITDRKV--ALEFLKSNVEANLPPHIQPKVVVKELTWGQNLDSFSP--------GEFDLILGADIIYLEDTFTDLLQTLGHLCSNN------SVILLACRIRYER-----DNNFLTMLERQFTVSKV------HYDPEKDVHIYKAQKRKQREDL-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQL0-1", "uniprot_id": "MT21A_MOUSE", "id": "Q9CQL0-1", "name": "Protein N-lysine methyltransferase METTL21A", "aln": "--------------------------------------------------------------------------MALVPYEESAAIG---------LQKFHKPLATFSFAN--------HTIQIRQDWR---QLGVAAVVWDAAVVLSMYLE------MGAVELRG----CSAVELGAGTGLVGIVAALL-------GAQVTITDRKV--ALEFLKSNVEANLPPHIQPKAVVKELTWGQNLESFSP--------GEFDLILGADVIYLEDTFTDLLQTLGHLCSNN------SVILLACRIRYER-----DSNFLTMLERQFTVSKV------HYDPEKDVHIYKAQKRNQREDL-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WXB1-1", "uniprot_id": "MT21A_HUMAN", "id": "Q8WXB1-1", "name": "Protein N-lysine methyltransferase METTL21A", "aln": "--------------------------------------------------------------------------MALVPYEETTEFG---------LQKFHKPLATFSFAN--------HTIQIRQDWR---HLGVAAVVWDAAIVLSTYLE------MGAVELRG----RSAVELGAGTGLVGIVAALL-------GAHVTITDRKV--ALEFLKSNVQANLPPHIQTKTVVKELTWGQNLGSFSP--------GEFDLILGADIIYLEETFTDLLQTLEHLCSNH------SVILLACRIRYER-----DNNFLAMLERQFTVRKV------HYDPEKDVHIYEAQKRNQKEDL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5BLD8-1", "uniprot_id": "MT21A_DANRE", "id": "Q5BLD8-1", "name": "Protein N-lysine methyltransferase METTL21A", "aln": "--------------------------------------------------------------------------MALVPYDENVLPA---------LSKLHQSSAEFTLAN--------HRIRLSQDWK---RLGVAAVVWDAAVVLCMFLE------MGKVDLKG----KRVIELGAGTGLVGIVAALL-------GANVTITDREP--ALEFLTANVHENIPQGRQKAVQVSELTWGENLDLYPQ--------GGYDLILGADIVYLEETFPALLQTLEHLSSGD------TVVLLSCRIRYER-----DERFLTELRQRFSVQEV------HYDSQRDIHVYRAVKNKSNTEL-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3YWP0-1", "uniprot_id": "EFMT3_MOUSE", "id": "D3YWP0-1", "name": "EEF1A lysine methyltransferase 3", "aln": "--------------------------------------------------------------------------MASSRTDPETEPESVFPREIRLFTDSYSESSRFCFCG--------HELSITQNFGS--RLGVAARVWDAALSLCDYFE------SQNVDFRG----KKVIELGAGTGIVGILAALQ-------GGDVTITDLPV--ALEQIQDNVHANVPPG--GRARVCALSWGIDQHVFP---------GNYDLVLGADIVYLEPTFPLLLGTLRHLCGPH------GTIYLASKMRAEHGA---ETFFRRLLPQHFHLELA------QRDEDVNVNIYRARHREVAPAGQHPFC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R8E0-1", "uniprot_id": "M0R8E0_RAT", "id": "M0R8E0-1", "name": "EEF1A lysine methyltransferase 3", "aln": "MVLCGSCSVCTRDPGSGVIPIHLQEIQLEEGGRTGEAGPDVWEQPIWLAVPSLNPAQIEGIRALAGVHGLSICRMASSHSDPESEPESVFPREVGLFTDSYSESSRFCFCG--------HELSITQNFGS--RLGVAARVWDAALSLCNYFE------SQNVDFRD----KKVIELGAGTGIVGILAAL--------GGDVTITDLPL--ALEQIQDNVHANVPPG--GRAQVCALSWGIDQHVFP---------GNYDLVLGADIVYLEPTFPMLLGTLRHLCGPH------GTIYLASKMRAEHGA---ETFFQHLLPQHFHLELA------QRDEDVNVNIYRARHR---PAGQHPFC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96AZ1-1", "uniprot_id": "EFMT3_HUMAN", "id": "Q96AZ1-1", "name": "EEF1A lysine methyltransferase 3", "aln": "--------------------------------------------------------------------------MADPGPDPESESESVFPREVGLFADSYSEKSQFCFCG--------HVLTITQNFGS--RLGVAARVWDAALSLCNYFE------SQNVDFRG----KKVIELGAGTGIVGILAALQ-------GGDVTITDLPL--ALEQIQGNVQANVPAG--GQAQVRALSWGIDHHVFP---------ANYDLVLGADIVYLEPTFPLLLGTLQHLCRPH------GTIYLASKMRKEHGT---ESFFQHLLPQHFQLELA------QRDEDENVNIYRARHREPRPA------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C436-1", "uniprot_id": "MT21D_MOUSE", "id": "Q8C436-1", "name": "Protein N-lysine methyltransferase METTL21D", "aln": "---------------------------------------------------------------------------MAAAVEPEVEDP-----------LWSFVRVLEKRDG--------TVLRLQQYGS----GGVGCVVWDAAIVLSKYLETPGFSGDGAHALSR----RSVLELGSGTGAVGLMAATL-------GADVIVTDLEE--LQDLLKMNIDMN-KHLVTGSVQAKVLKWGEDIEDLMSP----------DYILMADCIYYEESLEPLLKTLKDLSGSE------TCIICCYEQRTMGKNPEIEKKYFELLQLDFDFEEIPLDKHDEEYRSEDIHIVYIRKKKPKPPS-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZQ50-1", "uniprot_id": "A0A8I5ZQ50_RAT", "id": "A0A8I5ZQ50-1", "name": "", "aln": "---------------------------------------------------------------------------ISSAVEPEVEDP-----------LWSFVRVLEKRDG--------TALRLQQYGS----GGVGCVVWDAAIVLAKYLETPGFSGDGAHALSR----RSVLELGSGTGAVGLMAATL-------GADVIVTDLEE--LQDLLKMNINMN-KHLVTGSVQAKVLKWGDDIEDLMSP----------DYILMADCIYYEESLEPLLKTLKDLSGSE------TSIICCYEQRTMGKNPEIEKKYFELLQLDFDFEKIPLDKHDEEYRSEDIHILHIRKKNPKPPS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H867-4", "uniprot_id": "MT21D_HUMAN", "id": "Q9H867-4", "name": "Protein N-lysine methyltransferase METTL21D", "aln": "---------------------------------------------------------------------------MADTLESSLEDP-----------LRSFVRVLEKRDG--------TVLRLQQYSS----GGVGCVVWDAAIVLSKYLETPEFSGDGAHALSR----RSVLELGSGTGAVGLMAATL-------GADVVVTDLEE--LQDLLKMNINMN-KHLVTGSVQAKVLKWGEEIEGFPSPP---------DFILMADCIYYEESLEPLLKTLKDISGFE------TCIICCYEQRTMGKNPEIEKKYFELLQLDFDFEKIPLEKHDEEYRSEDIHIIYIRKKKSKFPS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53970-1", "uniprot_id": "EFM6_YEAST", "id": "P53970-1", "name": "Protein-lysine N-methyltransferase EFM6", "aln": "------------------------------------------------------------------------MESIFGGFGDLVVPR----------PKEHLGQTDLSFGG--------KLLPALKICEDGGESGCGGKVWIAGELLCEYILEKSVDHLLSKTVNGTKQFKKVLELGSGTGLVGLCVGLLEKNTFHDGTKVYVTDIDK--LIPLLKRNIELD---EVQYEVLARELWWGEPLSADFSPQEGAMQANNVDLVLAADCVYLEEAFPLLEKTLLDLTHCIN----PPVILMAYKKRRKA-----DKHFFNKIKRNFDVLEITDFSKFEHYLKERTHLFQLIRK-----------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VP86-1", "uniprot_id": "Q9VP86_DROME", "id": "Q9VP86-1", "name": "Methyltransferase-like protein 22", "aln": "------------------------------------------------------------------MFTVTSEIYGENNYQTTRDGGKVLSKFRFVYPEEKLAGIRTDKDGDLEVPRPKRGVIELEHSEATELRLVGLQVWRGALLLADYLFS------KKDEFSQ----KTLMELGAGVGLTSIAAGIHN------NGRIYCTDVDLGCILKLIRGNVQRN-SKLLRATISVLEFDFLASKEDHSQDLLEAID--NSDIILAADVIYCDTLTDAFICVLDNLLDRGRQTGRPKTIYMALEKRYVFT--LEDCDSVAPMYEYLIRQTVNKPWIMEHLPLDFPQYFEYDRCKQLVLMKIISR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . :* .. *. :: . :*:*:* * . : . . : ** : *: : . : : * :* :* :* . : .: : : . . * : : : : ", "identical_positions": 14, "similar_positions": 40, "identity": "3.88%" }, { "cls_id": "homologset.agr.SGD:S000004970", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62447-1", "uniprot_id": "CCNC_MOUSE", "id": "Q62447-1", "name": "Cyclin-C", "aln": "MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSE----------------------------------EEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAATTSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDVLLPLA-------WRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---------------------------RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P39947-1", "uniprot_id": "CCNC_RAT", "id": "P39947-1", "name": "Cyclin-C", "aln": "MAGNFWQSSHYLQWILDK-----ERQKDLKFLSE----------------------------------EEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTSLIAATTSVLKTRFSYASPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDVLLPLA-------WRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---------------------------RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24863-1", "uniprot_id": "CCNC_HUMAN", "id": "P24863-1", "name": "Cyclin-C", "aln": "MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSE----------------------------------EEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLA-------WRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---------------------------RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25008-1", "uniprot_id": "CCNC_DROME", "id": "P25008-1", "name": "Cyclin-C", "aln": "MAGNFWQSSHSQQWILDKPDLLRERQHDLLALNE----------------------------------DEYQKVFIFFANVIQVLGEQLKLRQQVIATATVYFKRFYARNSLKNIDPLLLAPTCILLASKVEEFGVISNSRLISICQSAIKTKFSYAYAQEFPYRTNHILECEFYLLENLDCCLIVYQPYRPLLQLVQDMGQEDQLLTLS-------WRIVNDSLRTDVCLLYPPYQIAIACLQIACVILQKDAT--------------------------KQWFAELNVDLDKVQEIVRAIVNLYELWKDWKEKDEIQMLLSKIPKPKPPPQR-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47821-1", "uniprot_id": "SSN8_YEAST", "id": "P47821-1", "name": "RNA polymerase II holoenzyme cyclin-like subunit", "aln": "MSGSFWTSTQRHHWQYTKASLAKERQKLWLLECQLFPQGLNIVMDSKQNGIEQSITKNIPITHRDLHYDKDYNLRIYCYFLIMKLGRRLNIRQYALATAHIYLSRFLIKASVREINLYMLVTTCVYLACKVEECPQYIRTLVSEART---------LWPEFIPPDPTKVTEFEFYLLEELESYLIVHHPYQSLKQIVQVLKQPPFQITLSSDDLQNCWSLINDSYINDVHLLYPPHIIAVACLFITISIHGKPTKGSSLASAASEAIRDPKNSSSPVQIAFNRFMAESLVDLEEVMDTIQEQITLYDHWDKYHEQWIKFLLHTLYLRPASAI-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*.** *:: :* * ***: : :: :: *: :* **.:*::** .:*** :*:.** : *::.*: ::..**: **.**** .: : .: :* .:: * ****** ::. ***::**:.* * ** : * :.*: * ::**: .*: *****. **:*** :: : * : .:::** **:::: : :: :.**: *..:.*: : : :* .. ", "identical_positions": 76, "similar_positions": 88, "identity": "21.65%" }, { "cls_id": "homologset.agr.SGD:S000004971", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AXV4-1", "uniprot_id": "SAM50_RAT", "id": "Q6AXV4-1", "name": "Sorting and assembly machinery component 50 homolog", "aln": "MGTVHARSLEPLPSSGTDFGALGEEAEFVEVEPEAKQEILENKDVVVQHVHFDGLERTKDDIIIC--EIGEVFKAKNLIEVMRRSHEAREKLLRLGIFRQVDVLIDTCHGEDALPNGLDVT-FEVTELRRLTGSYNTMVGNNEGSMVLGLKLPNLLGRAEKVTFQFSYG-TKETSYGLSFFKPQPGN-FEKN---FSVNLYKVTGQFPWSSLRETDRG---------------VSAEYSFPLCK---TSHTVKWEGVWRELGCLAR--TASFAVR----KESGHSLKSSLSHAMVIDSRNSSILPRRGALLKVNQELAGYTGGDVSFIKEDFELQLNKPLVLDSVFSTSLWGGMLVPIG-DKLSSIADRFYLGGPTSVRGFSMHSIGPQSEGDYLGGEAYWAGGLHLYTPLPFRPGQGGFGELFRTHFFLNAGNLCNLNYGEGPRAHIRKLAECIRWSYGAGIVLRLGNIARLELNYCIPMGVQRGDRICDGVQFGAGIRFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGH2-1", "uniprot_id": "SAM50_MOUSE", "id": "Q8BGH2-1", "name": "Sorting and assembly machinery component 50 homolog", "aln": "MGTVHARSLEPLPSSGTDFGALGEEAEFVEVEPEAKQEILENKDVVVQHVHFDGLGRTKDDIIIC--EIGEVFKAKNLIEVMRRSHEAREKLLRLGIFRQVDVLIDTCHGEDALPNGLDVT-FEVTELRRLTGSYNTMVGNNEGSMVLGLKLPNLLGRAEKVTFQFSYG-TKETSYGLSFFKPQPGN-FERN---FSVNLYKVTGQFPWSSLRETDRG---------------VSAEYSFPLWK---TSHTVKWEGVWRELGCLSR--TASFAVR----KESGHSLKSSLSHAMVIDSRNSSILPRRGALFKVNQELAGYTGGDVSFIKEDFELQLNKPLALDSVFSTSLWGGMLVPIG-DKPSSIADRFYLGGPTSVRGFSMHSIGPQSEGDYLGGEAYWAGGLHLYTPLPFRPGQGGFGELFRTHFFLNAGNLCNLNYGEGPKAHIRKLAECIRWSYGAGVVLRLGNIARLELNYCIPMGVQGGDRICDGVQFGAGIRFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y512-1", "uniprot_id": "SAM50_HUMAN", "id": "Q9Y512-1", "name": "Sorting and assembly machinery component 50 homolog", "aln": "MGTVHARSLEPLPSSGPDFGGLGEEAEFVEVEPEAKQEILENKDVVVQHVHFDGLGRTKDDIIIC--EIGDVFKAKNLIEVMRKSHEAREKLLRLGIFRQVDVLIDTCQGDDALPNGLDVT-FEVTELRRLTGSYNTMVGNNEGSMVLGLKLPNLLGRAEKVTFQFSYG-TKETSYGLSFFKPRPGN-FERN---FSVNLYKVTGQFPWSSLRETDRG---------------MSAEYSFPIWK---TSHTVKWEGVWRELGCLSR--TASFAVR----KESGHSLKSSLSHAMVIDSRNSSILPRRGALLKVNQELAGYTGGDVSFIKEDFELQLNKQLIFDSVFSASFWGGMLVPIG-DKPSSIADRFYLGGPTSIRGFSMHSIGPQSEGDYLGGEAYWAGGLHLYTPLPFRPGQGGFGELFRTHFFLNAGNLCNLNYGEGPKAHIRKLAECIRWSYGAGIVLRLGNIARLELNYCVPMGVQTGDRICDGVQFGAGIRFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803G5-1", "uniprot_id": "SAM5A_DANRE", "id": "Q803G5-1", "name": "Sorting and assembly machinery component 50 homolog A", "aln": "MGTVHARSLDPLPMQGPELGVQADDMDLGEPEREEKQEVLENKDVVVQHVHIDGLGRTKEDILTY--EIADVFHAKNLIDVMKKSHEARQKLLRLGIFRHVEVVIDTAEGADALPNGLDVT-FEVRELRRMTGSYNTMVGNNEGSMVLGIKLPNVLGRAEKLTFQFSYG-TKETSYGLSFFKPQPGH-FERN---FSLNLYKVTGQFPWSSLRETDRG---------------VSAEISFPIWR---TSHTLKWEGVWRELGCLAR--TASFAVR----EESGHSLKSSLAHAMVIDTRNSTILPRKGALLKINQELAGYTGGDVSFLKEDFEIQLNKTLFWDSVLSTSLWGGMLLPLG-EKASSIADRFYLGGPTSVRGFSMYSIGPQSEGDYLGGEAYWAGGVHLYTPLPFRPGRGGFGDLFRTHFFLNAGNLCNLNYGEGPRAHLSKLAECIRWSYGAGIVLRLGNIARLELNYCIPMGVQSGDRICDGVQFGAGIRFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5U3I0-1", "uniprot_id": "SAM5B_DANRE", "id": "Q5U3I0-1", "name": "Sorting and assembly machinery component 50 homolog B", "aln": "MGTVHARSMDSYPMYGRDLGVNTDDMEVMEAVQETKQEVLENKDVVVQHVNIEGLGRTKEDYLGY--EISDVFTARNLVEVMRKSHEARQRLLRLGIFRDVEVVIDISEGADALPNGLDVT-FEVTELKRLTGSYNTMVGNNEGSMVLGIKLPNMLGRGEKLTFQFSYG-TKETSYGLSFFKPQSGY-FERN---FTVNLYKVTGQFPWSSLKETDRG---------------VSTELSLPLWM---TDHTLKWEGVWRELGCLAR--SASFAVR----EESGHTLKSALSHTMVVDTRNSAILPRKGALLRINQELAGYTGGDANFLKEDVELQLNKQFIWGSVLSASLWGGMIYPLG-AQPTSIADRFYLGGPTSVRGFGMYSIGPQSEGDYLGGEAYWAGGLHLYTPLPFRSNKGGLADLFRTHFFLNAGNICNLNYGEGPRAHLQKLAECIRWSYGAGIILRLGNIARLELNYCFPMGVQSGDRICDGVQFGAGIRFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V784-1", "uniprot_id": "SAM50_DROME", "id": "Q9V784-1", "name": "SAM50-like protein CG7639", "aln": "-----------MPKSGRDGGAS-----------KDSKYDLSKISARVDRVNVSGLLRTHNDYVMR--AADGLFKASNFQDLMLEAMSTKSYLHELGIFKDVSVHIDVSRGADASPQGYEVT-FKGNEMSRMMGSAGTEIGQNEGSLRTELTIPNILGRGENISLQGSYSSTRANDLQLKFWKPFFHTRFKENRPEMSFSIFRQTDRFDISSFQTTNIG---------------YLVDFSAHTMVGVDLTHSLQYENAIRDVGLLNK--SVPFAIR----DHCGPKLASLLRYSVVYDNRDGNVFPTRGIYLKSVNEYCG-LGGNVAYTSSTAHGELNVPLFAGLVAQFCARVGVVKETKNTTQLPISSLFYCGGPLTLRGFKFGGAGPVVESTPIGAQSFWCTGAHLWAPLPFAGVFKNLASHFRMHFFYNIGNNNSFS------------TENMRSAFGMGLAVKLAERARIELNYCVPVRHQDTDRILNGFQFGIGYEFV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53969-1", "uniprot_id": "SAM50_YEAST", "id": "P53969-1", "name": "Sorting assembly machinery 50 kDa subunit", "aln": "--------MTSSSGVDNEISLDSPMPIFNESSTLKPIRVAGVVTTGTDHIDPSVLQAYLDDTIMKSITLGQLVKNADVLNKRLCQHHIALNAKQSFHFQGNTYISDEKETHDVVPLMEVVSQLDILPPKTFTAKTGTNFGNDNDAEAYLQFEKLIDKKYLKLPTRVNLEILRGTKIHSSFLFNSYSSLSPQS----ILNLKVFSQFYNWNTNKGLDIGQRGARLSLRYEPLFLHKLLHNPHSNESPTLFHEWFLETCWRSTKICSQGTSAPYMYSGTMLSQAGDQLRTILGHTFVLDKRDHIMCPTKGSMLKWSNELSPGKHLKTQLELNSVKSWMNDDFITFSTTIKTGYLKNLSSQQ-SLPVHICDKFQSGGPSDIRGFQTFGLGPRDLYDAVGGDAFVSYGLSVFSRLPWKKVEK---SNFRLHWFFNGGKLVNHDN-TSLGNCIGQLSKEHSTSTGIGLVLRHP-MARFELNFTLPITAHENDLIRKGFQFGLGLAFL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . . .:::. . * :* : :. :. : . *: * . *. * *: :. : .. .* .*:::.: : : ::. : . : .. .* .. ..: : : .: : : * . * * *. : :..: ...* * : * ::.* *.*: : * :* :: :* . .. . . :* : . : *.. * *** :*** . ** :*.::: . * ::: **: . ** *:* * *: . . :: : * *: :: **:***: .*: : * * .*.*** * *:", "identical_positions": 60, "similar_positions": 120, "identity": "11.95%" }, { "cls_id": "homologset.agr.SGD:S000004972", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NQX0-3", "uniprot_id": "PRDM6_HUMAN", "id": "Q9NQX0-3", "name": "Putative histone-lysine N-methyltransferase PRDM6", "aln": "-------------------------------------MLKPGDPGGSAFLKVDPAYLQHWQQLFPHGGAGPLKGSGAAGLLSAPQP-LQPPPPPP-PPERAEPPPDSLRPRPASLSSASSTPASSSTSASSASSCAAAAAAAALAGLSALPVSQLPVFAPLAAAA---VAAEPLPPKELCLGATSGPGPVKCGGGGGGGGEGRGAPRFRCSAEELDYYLYGQQRMEIIPLNQHTSDPNNRCDMCADNRNGECPMHGPLHSLRRLVGTSSAAAAAPPPELPEWLRDLPREVCLCTSTVPGLAYGICAAQRIQQGTWIGPFQGV---LLPPEKVQAGAVRNTQHLWEIYDQDGTLQHFIDGGEPSKSSWMRYIRCARHCGEQNLTVVQYR---SNIFYRACIDIPRGT-ELLVWYNDSYTSFFGIPLQCIAQDENLNVPSTVMEAMCRQDALQPFNKSSKLAPTTQQRSVVFPQTPCSRNFS-------LLDKSGPIESGFNQINVKNQRVLASP------------TSTSQLHSEFSDWHLWKCGQCFKTFTQRILLQMHVCTQNPDRPYQCGHCSQSFSQPSELRNHVVTHSSDRPFKCGYCGRAFAGATTLNNHIRTHTGEKPFKCER---------CERSFTQATQLSRHQRMPNECKPITESPESIEVD------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDZ3-1", "uniprot_id": "SQZ_DROME", "id": "Q9VDZ3-1", "name": "Zinc finger protein squeeze", "aln": "------------------------------------MAELPTAPNG----VPSGDYLHRSIDQLRS-----LGHLTTAQLVHDYKP-FNISEFRQNVAERLDYSLKNGLVQHQQQMVMEQQPHPDQQQQQHLHHPQQQQHPPQLK-VSYSAPNSPPTPHEQQEQK---YDPNRSPPRQQMSSASGSGSNGSSPEEESRRGDGDQAKPYKCGSCSKS---FANSSYLSQHTRIHLGIKPYRCEICQRKFTQLSHLQQHIR-----THTGDKPYKCRHAGCPKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEMT---------LLEHIPKHKDSKHLKTHICNLCGKSYTQETYLQ------KHLQKHAEKAEKQQHRHTAQVAAH---QQHVPASGIGLNLQR-QAMNDVNAAYWAKMGADSAAAS-------LAEAIQQQLPQAGGQPYGNFASLQQQHQQQ-----QQELLHHQR-------LADTPGHSHSPHEEAAG-EDLVLRQS------------TPQHHLQQQQ--------QQQQQQQAQQQQQAQHQPSPGPGN-SAFTPLSATVAPPPHLQQHRGPPGSAAAYLYQQN--AAAAAAAFPTQLISLHQIRNYAHQP---------GAAGLIAGDHLALGLSAVNAAKEKAQ--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53968-1", "uniprot_id": "CRZ1_YEAST", "id": "P53968-1", "name": "Transcriptional regulator CRZ1", "aln": "MSFSNGNMASYMTSSNGEEQSINNKNDIDDNSAYRRNNFRNSSNSGSHTFQLSDLDLDVDMRMDSANSSEKISKNLSSGIPDSFDSNVNSLLSPSSGSYSADLNYQSLYKPDLPQQQLQQQQLQQQQQQQQQQQQQQQKQTPTLKVEQSDTFQWDDILTPADNQHRPSLTNQFLSPRSNYDGTTRSSGIDSNYSDTESNYHTPYLYPQDLVSSPAMSHLTANNDDFDDLLSVASMNSNYLLPVNSHGYKHISNLDELDDLLSLTYSDNNLLSASNNSDFNNSNNGIINTADTQNSTIAINKSKVGTNQKMLLTIPTSSTPSPSTHAAPVTPIISIQEFNEGHFPVKNEDDGTLQLKVRDNESYSATNNNNLLRPDDNDYNNEALSDIDRSFEDIINGRKLKLKKSRRRSSQTSNNSFTSRRSSRSRSISPDEKAKSISANREKLLEMADLLPSSENDNNRERYDNDSKTSYNTINSSNFNEDNNNNNLLTSKPKIESGIVNIKNELDDTSKDLGILLDIDSLGQFEQKVGFKNDDNHENNDNGTFSVKKNDNLEKLDSVTNNRKNPANFACDVCGKKFTRPYNLKSHLRTHTNERPFICSICGKAFARQHDRKRHEDLHTGKKRYVCGGKLKDGKPWGCGKKFARSDALGRHFKTESGRRCITPLYEEARQEKSGQES", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* . *. : :: : .. .: . : .. .. .. . . .. * . . . : .*:. .:: . . . . : .:. : . . :. .. . . : : . . . : : *: .. * : : . . . .: : .: . : : . * :: : . . : : : * .: . :: : : * . .* : : . . ::.: : : . . ..: * .*:.* . . .: * * : : : : . *. . : : ", "identical_positions": 16, "similar_positions": 122, "identity": "2.36%" }, { "cls_id": "homologset.agr.SGD:S000004975", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62805-1", "uniprot_id": "H4_HUMAN", "id": "P62805-1", "name": "Histone H4", "aln": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62804-1", "uniprot_id": "H4_RAT", "id": "P62804-1", "name": "Histone H4", "aln": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P84040-1", "uniprot_id": "H4_DROME", "id": "P84040-1", "name": "Histone H4", "aln": "MTGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P62806-1", "uniprot_id": "H4_MOUSE", "id": "P62806-1", "name": "Histone H4", "aln": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02309-1", "uniprot_id": "H4_YEAST", "id": "P02309-1", "name": "Histone H4", "aln": "MSGRGKGGKGLGKGGAKRHRKILRDNIQGITKPAIRRLARRGGVKRISGLIYEEVRAVLKSFLESVIRDSVTYTEHAKRKTVTSLDVVYALKRQGRTLYGFGG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*******************:********************************.*.*** ***.****:*************::******************", "identical_positions": 94, "similar_positions": 8, "identity": "91.26%" }, { "cls_id": "homologset.agr.SGD:S000004976", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P02301-1", "uniprot_id": "H3C_MOUSE", "id": "P02301-1", "name": "Histone H3.3C", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALTKQTARKSTGGKAPRKQLATKATRKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIR--------------------------------KLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZK97-1", "uniprot_id": "D3ZK97_RAT", "id": "D3ZK97-1", "name": "Histone H3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARTKQTARKSTGGKAPRKQLATKATRKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIR--------------------------------KLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6A289-1", "uniprot_id": "A0A8I6A289_RAT", "id": "A0A8I6A289-1", "name": "Histone H3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARTKQTARKSTGGKAPRKQLATKASHKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIR--------------------------------KLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRILGERA-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P84243-1", "uniprot_id": "H33_HUMAN", "id": "P84243-1", "name": "Histone H3.3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIR--------------------------------KLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P84245-1", "uniprot_id": "H33_RAT", "id": "P84245-1", "name": "Histone H3.3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIR--------------------------------KLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PI20-1", "uniprot_id": "H33_DANRE", "id": "Q6PI20-1", "name": "Histone H3.3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIR--------------------------------KLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "C0HL66-1", "uniprot_id": "H33A_DROME", "id": "C0HL66-1", "name": "Histone H3.3A", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIR--------------------------------KLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "C0HL67-1", "uniprot_id": "H33B_DROME", "id": "C0HL67-1", "name": "Histone H3.3B", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIR--------------------------------KLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P84244-1", "uniprot_id": "H33_MOUSE", "id": "P84244-1", "name": "Histone H3.3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIR--------------------------------KLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NXT2-1", "uniprot_id": "H3C_HUMAN", "id": "Q6NXT2-1", "name": "Histone H3.3C", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVK-PHRYRPGTVALREIRRYQKSTELLIR--------------------------------KLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P84228-1", "uniprot_id": "H32_MOUSE", "id": "P84228-1", "name": "Histone H3.2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIR--------------------------------KLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02299-1", "uniprot_id": "H3_DROME", "id": "P02299-1", "name": "Histone H3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIR--------------------------------KLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q71DI3-1", "uniprot_id": "H32_HUMAN", "id": "Q71DI3-1", "name": "Histone H3.2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIR--------------------------------KLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P68433-1", "uniprot_id": "H31_MOUSE", "id": "P68433-1", "name": "Histone H3.1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIR--------------------------------KLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P68431-1", "uniprot_id": "H31_HUMAN", "id": "P68431-1", "name": "Histone H3.1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIR--------------------------------KLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I4SYN6-1", "uniprot_id": "A0A8I4SYN6_MOUSE", "id": "A0A8I4SYN6-1", "name": "Histone H3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARTKQTARKSTGGKAPRKQLATKVARKSAPATGGVKKPHRYHPGTVALREIRRYQKSTELLIR--------------------------------KLPFQRLVREIAQDFKTDLRFQSSAVMALQEACESYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16695-1", "uniprot_id": "H31T_HUMAN", "id": "Q16695-1", "name": "Histone H3.1t", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARTKQTARKSTGGKAPRKQLATKVARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIR--------------------------------KLPFQRLMREIAQDFKTDLRFQSSAVMALQEACESYLVGLFEDTNLCVIHAKRVTIMPKDIQLARRIRGERA-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5TEC6-1", "uniprot_id": "H37_HUMAN", "id": "Q5TEC6-1", "name": "Histone H3-7", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIR--------------------------------KLPFQRLVREIAQEFKTDLRFQSSAVMALQEAREAYLVGLFEDTNLCAIHAKRVTIMPKDIQLVSRIRGERA-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61830-1", "uniprot_id": "H3_YEAST", "id": "P61830-1", "name": "Histone H3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARTKQTARKSTGGKAPRKQLASKAARKSAPSTGGVKKPHRYKPGTVALREIRRFQKSTELLIR--------------------------------KLPFQRLVREIAQDFKTDLRFQSSAIGALQESVEAYLVSLFEDTNLAAIHAKRVTIQKKDIKLARRLRGERS-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0DPK2-1", "uniprot_id": "H3Y1_HUMAN", "id": "P0DPK2-1", "name": "Histone H3.Y", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARTKQTARKATAWQAPRKPLATKAAGKRAPPTGGIKKPHRYKPGTLALREIRKYQKSTQLLLR--------------------------------KLPFQRLVREIAQAISPDLRFQSAAIGALQEASEAYLVQLFEDTNLCAIHARRVTIMPRDMQLARRLRREGP-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DPK5-1", "uniprot_id": "H3Y2_HUMAN", "id": "P0DPK5-1", "name": "Histone H3.X", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARTKQTARKATAWQAPRKPLATKAARKRASPTGGIKKPHRYKPGTLALREIRKYQKSTQLLLR--------------------------------KLPFQRLVREIAQAISPDLRFQSAAIGALQEASEAYLVQLFEDTNLCAIHARRVTIMPRDMQLARRLRGEGAGEPTLLGNLAL--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q00729-1", "uniprot_id": "H2B1A_RAT", "id": "Q00729-1", "name": "Histone H2B type 1-A", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPEVSAKGTTISKKGFKKAVTKTQKKEGRKR---KRCRKESYSIYIYKVLKQVHPDTGISSK--------------------------------AMS---IMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1NED1-1", "uniprot_id": "A0A8M1NED1_DANRE", "id": "A0A8M1NED1-1", "name": "", "aln": "MLRNKHDETPQVDADREEEYHFSSEEEQEDDIEDDEYEEETADSSDDCDNDSEQIPVAKRAKTVSWRTERDADKLPKNLRFQPAREPGPQLSPADPLNPLSLFKLFFSKSVVSNLCKNTNAQAARAMAKQCKYPWTDVSVEELYHYIGLIFYMDVVRMYSVADYWRQDPFFSVPFPSTVMSMDRYHAILCNLHLSDPNADENDGDTLFKVKSLMDSIRQACSAHYQPRRNVVVSERFVLRKVKPVIKAKLGFRFFVLIDSSNGYTADVSVYKTSFPPRPGFSYDTVMSLLDAKALGSGYHVYMDDFYTTPKLMKDLFALKFGACGMYRDQRKDFPRNKSNPLTEKSARGSYRWIRDGPVVFVKWMDRPEVSICSTIHQAYTGEHVERKVRRQGSRKTKSIPCPAPVSAYSQHIVEVDPFDQLLQYYIMHYNSLKWYKKVFLQFLDIAAANAFILHKEQGGKLTHKKFMDQLIEELCS-VSEEVPEQSSIQVEHLPVSGALLESHTATTGRQACSQCKKQDIRQLTPWKCQACHVFLCVEVDRNRFLDWHKNIACSGL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : : : *. : : . :. :: .: : : : . : : .. : . ", "identical_positions": 1, "similar_positions": 25, "identity": "0.18%" }, { "cls_id": "homologset.agr.SGD:S000004980", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVP5-1", "uniprot_id": "WDR89_RAT", "id": "Q5FVP5-1", "name": "WD repeat-containing protein 89", "aln": "MEKIKDQFANLHILRRSSEPKEPTYLLGIDTSKTVPAEKGGLVAVLCSNGSIRIYDKETLNLLREFSGSPGLLNGVRFAN---SCDNVYSASTDGTVKCWDARLASEKPAQLFKGYPSNIFISFDVNCKDHIICAGAEKVEDDALLVFWDARFTSQDLS-TRDPLGAYSETHSDDITQVRFHPSNPNMVVSGSTDGLVNVFDLSVDNEEDALVATCNSVSSVSCIGWCGRDYKQIYCMTHDEGFCWWDLN----HLDTDEPITCLNIQDVRDVTDVKEGHLDYLIGGLYHENMDRLFVIGGTNL-----GKIHLLSCTKTGLSHVTSLQGGHAATVRSFC-------WTVSEDSLLTGG----EDAQLLLWKPGAVEKTFTKKDSLKIAS-SVQQRVRVHSSDSYKKRKQQ------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0R9-1", "uniprot_id": "WDR89_MOUSE", "id": "Q9D0R9-1", "name": "WD repeat-containing protein 89", "aln": "MEKIEDQFASLHIVRRSSEPKEPTYLLGIDTSKTVQADKGGLVAVLCSNGSIRIYDKETLHLLREFGGSPGLLSGVSFAN---SCDSVYSASTDGTVKCWDARGASEKPVQLFKGYPSCSFISFDVNCKDHVICAGAEKVDEDALLVFWDARFTSQDLS-TRDPLGAYSETHSDDITQVRFHPSNPNLVVSGSTDGLVNVFDLSADKEEDALVATCNSVSSVSCIGWCGKDYKQIYCMTHDEGFCWWDLN----HLDTDEPITCLNIQDVREITDVKDGHLDYLIGGLYHEKMDRLFVIGGTNT-----GKIHLLSCTSAGLTHVTSLHGGHAATVRSFC-------WNVSEDSLLTGG----EDAQLLLWKPGAMEKTFTKKDSLKIAS-SVQQRVRVHSSDSYKKRKQQ------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96FK6-1", "uniprot_id": "WDR89_HUMAN", "id": "Q96FK6-1", "name": "WD repeat-containing protein 89", "aln": "MEKIEEQFANLHIVKCSLGTKEPTYLLGIDTSKTVQAGKENLVAVLCSNGSIRIYDKERLNVLREFSGYPGLLNGVRFAN---SCDSVYSACTDGTVKCWDARVAREKPVQLFKGYPSNIFISFDINCNDHIICAGTEKVDDDALLVFWDARMNSQNLSTTKDSLGAYSETHSDDVTQVRFHPSNPNMVVSGSSDGLVNVFDINIDNEEDALVTTCNSISSVSCIGWSGKGYKQIYCMTHDEGFYWWDLN----HLDTDEPVTRLNIQDVREVVNMKEDALDYLIGGLYHEKTDTLHVIGGTNK-----GRIHLMNCSMSGLTHVTSLQGGHAATVRSFC-------WNVQDDSLLTGG----EDAQLLLWKPGAIEKTFTKKESMKIAS-SVHQRVRVHSNDSYKRRKKQ------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53962-1", "uniprot_id": "YND5_YEAST", "id": "P53962-1", "name": "Uncharacterized WD repeat-containing protein YNL035C", "aln": "-------MASYSLVESNSFGSE-NWCLKLQP-----SYKHGLLTGLS-NGEIRLLDWSTGKSVQKIKASETAINDMKVIGSDFSAGHLVSSASIDAVKVFDIRTN--DRIAQIQNEANSPFISLDS--RHGLLACGTELQGIDAAVYIYDIRKWD-------TPLRSLIDSHHDDVTCIKFHPSDVNILLSGSTDGYTNIYDLKQDEEEDALHQVIN-YASIHSCGWLSP--KRIFTLSHMETFAIHELNDKSDELKEPQPLDFGDVREIWNCDYVVDIYPGLIATGKTQENCGELCLLPFKDEKVDTENGIVIPHAHGDEVVRDIFIPAQHSNMLYSCGEDGCVKIWENKQGPLDIPENFWDYSKKMNVLGDDDREGSINLDEPLIIQKESVSTRPRKEKHKKAKKHSMKSRFKPY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. ::. . .* .: * ::. : * .*:: *. **.**: * . : :::: . :..: . . *.. : *:.: .:** :* * . ::. .. ***:* .. ::..*:* ** : ::* * . .* : ::* **:* ::****: *:::***:** .*::*:. *:***** . * :*: . ** . *:*: ::* * * :** .*. :*: ::::: : : : . : * :*: . * :: .: . * : . : : : . *: : * * .:..* . :: : . * ::. .:.: * . ** * * .. .. *::. : ", "identical_positions": 78, "similar_positions": 142, "identity": "18.71%" }, { "cls_id": "homologset.agr.SGD:S000004981", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VHJ5-1", "uniprot_id": "Q9VHJ5_DROME", "id": "Q9VHJ5-1", "name": "Carbonic anhydrase", "aln": "-----------------MERILRGIMRYRNTTREQMVKEFQKVRDNPE-PKAVFFTCMDSRMIPTRYTDTHVGDMFVVRNAGNLIPHAQHFQDEYFSCEPAALELGCVVNDIRHIIVCGHSDCKAMNLLYQLRDPDFASKLNRRLSPLRSWLCTHANTSLERFQEWRDAGMKDPLIFSSETPLRRFVAYIDEEQKFALEDKLSQINTLQQMSNIASYGFLKARLESHDLHIHALWFDIYTGDIYYFSRGAKRFLPVDEDTVDRLSEEVRRFYS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53615-1", "uniprot_id": "CAN_YEAST", "id": "P53615-1", "name": "Carbonic anhydrase", "aln": "MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNEN-CLGVLPGEVFTWKNVAN-ICHSEDLT------LKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALP-KVN----------CSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKR---------------QFNRIIENPTVQTAVQNGELQVYGLLYNVEDG------------LLQTVSTYTKVTPK------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ** . :: . .: . * . . : : *:::*: * *** . .. *::*. :*..* * *::.: *:**:. : .:.::*:***:** .:: : :. *:* *:* . *: :: . :: : :.:: ::::: : :: *:..* . ::: ::. :*:::.* ::: * * .* ::: : ", "identical_positions": 36, "similar_positions": 92, "identity": "13.19%" }, { "cls_id": "homologset.agr.SGD:S000004982", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4QQT5-1", "uniprot_id": "IDHG2_RAT", "id": "Q4QQT5-1", "name": "Probable isocitrate dehydrogenase [NAD] gamma 2, mitochondrial", "aln": "----MLAAGSCSVRTILQPALLLGHSREVVCELVTSFRN--FCSKYSVPPSPKYGGKHTVTMIPGD-GIGPELMVHVKRIFRSNCVPVEFEEVWATST---SSEEEINNALMAIRRNRITLKGNIATN-HHLPAKYKSHNTKFRTALDLYASVVHFKTFPGVETRHKDIDILVVRENTEGEYTNLEHESVRGVVESLKIVTKTKSVRIADYAFRLAQKMGRKKVTVVHKANIMKLGDGLFLQCCKDVAAH-YPQITLESMIIDNTAMQLVSKPQQFDVMLMPNLYGNIINSVCTGLVGGSGIVPGANYGDSYAIFETGSKEIGQDLAHRNIANPVAMLLTSCIMLDYLDLQLYAAHIRSAVMASLQNKSICTPDIGGQGTTAGVVEYILDHMKDQNSGCQPRFFLST-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BPC6-1", "uniprot_id": "IDHG2_MOUSE", "id": "Q8BPC6-1", "name": "Probable isocitrate dehydrogenase [NAD] gamma 2, mitochondrial", "aln": "----MLAVTSCSMKTVLQYAVFLGHSREVVCELVTSFRS--FCSHCAVPPSPKYGGRHTVAMIPGD-GIGPELMVHVKKIFRSNCVPVDFEEVWVTST---SNEEEINNALMAIRRNRVALKGNIATN-HNLPARYKSHNTKFRTILDLYASVVHFKTFPGVMTRHKDIDILVVRENTEGEYTNLEHESVKGVVESLKIVTKTKSVRIADYAFKLAQKMGRKKVTVVHKANIMKLGDGLFLQCCKDVAAH-YPQITLESMIIDNTTMQLVSKPQQFDVMVMPNLYGNIINSICTGLVGGSGIVPGANYGDSYAIFEMGSKEIGKDLAHRNIANPVAMLLTSCIMLDYLDLQPYATHIRSAVMASLQNKAVCTPDIGGQGNTASTVEYILHHMKEQTSGCHPNFFLQFT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P70404-1", "uniprot_id": "IDHG1_MOUSE", "id": "P70404-1", "name": "Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial", "aln": "MALKVAIAAGGAAKAMLKP-TLLCRPWEVLAAHVAPRRS--ISSQQTIPPSAKYGGRHTVTMIPGD-GIGPELMLHVKSVFRHACVPVDFEEVHVSSN---ADEEDIRNAIMAIRRNRVALKGNIETN-HNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAAH-YPQITFDSMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSQAIQDIIRHIRIINGRAVEA------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41565-1", "uniprot_id": "IDHG1_RAT", "id": "P41565-1", "name": "Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial", "aln": "MALKVAIAAGSAAKAIFKP-ALLCRPWEVLAAHEAPRRS--ISSQQTIPPSAKYGGRHTVTMIPGD-GIGPELMLHVKSVFRHACVPVDFEEVHVSSN---ADEEDIRNAIMAIRRNRVALKGNIETN-HDLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAAR-YPQITFDSMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSQAIQDIIRHIRIINGRAVEA------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51553-1", "uniprot_id": "IDH3G_HUMAN", "id": "P51553-1", "name": "Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial", "aln": "MALKVATVAGSAAKAVLGP-ALLCRPWEVLGAHEVPSRN--IFSEQTIPPSAKYGGRHTVTMIPGD-GIGPELMLHVKSVFRHACVPVDFEEVHVSSN---ADEEDIRNAIMAIRRNRVALKGNIETN-HNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAAR-YPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVINGRAVEA------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QZA4-1", "uniprot_id": "F1QZA4_DANRE", "id": "F1QZA4-1", "name": "Isocitrate dehydrogenase [NAD] subunit, mitochondrial", "aln": "----MMATLTKALKPILG--RQLGNTAKVFGAGVVSQRGKPTYSGRIIPPPAKYGGRHTVTLIPGD-GIGPELLNHVRELFRFSCVPVDFEVVHVNSSS--TSEDDISNAIMAIRRNGVALKGNIETN-HTMPPNHKSRNNLLRTSLDLYANVMHCQSLPGVQTRHKNIDIIIIRENTEGEYSSLEHESASGVVECLKIITRNNSLRIADYAFKLAREKGRRRVTAVHKANIMKLGDGLFLQCCKEVASG-YPDIEFENMIVDNTTMQLVSKPYQFDVMVMPNLYGNVVSNVCAGLVGGPGLVPGANYGRDYAVFETATRNTGKSIANRNIANPTAMLLASCLMLDHLKLHDYANMIRSAILTTMNETRLHTVDIGGQGTTSEVVQSIMRIIQSGGPLTKEI------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O43837-1", "uniprot_id": "IDH3B_HUMAN", "id": "O43837-1", "name": "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "aln": "------MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAH---AASRSQAEDVRVEGSFPVTMLPGD-GVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTP-MEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAEL-YPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSVIGHLQTKGS-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q68FX0-1", "uniprot_id": "IDH3B_RAT", "id": "Q68FX0-1", "name": "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "aln": "------MAALSNVRWLTRAVLGARNSGAWRGLRTAASAQ---AASQSQAQDVRVEGAFPVTMLPGD-GVGPELMHAVKEVFKAAAVPVEFKEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIYTP-MEYKGELASYDMQLRRKLDLFANVVHVKSLPGYKTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRTKSQRIAKFAFDYATKKGRSKVTAVHKANIMKLGDGLFLQCCEEVAEL-YPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSVIGHLHPHGG-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VD58-1", "uniprot_id": "Q9VD58_DROME", "id": "Q9VD58-1", "name": "Isocitric dehydrogenase subunit beta", "aln": "------MSMLA--RTVGRTFMQA---AAARSLHTTSTLR---ATDNYGANRT------TCTLIPGD-GVGPELVYSLQEVFKAASVPVDFECYFLSEINPVLS-AKLEDVVASIQKNKVCIKGVLATPDYSNVGDLQTLNMKLRNDLDLYANVVHVRSLPGVKTRHTNIDTVIIREQTEGEYSALEHESVPGIVECLKIITAKKSMRIAKFAFDYATKNQRKKVTAVHKANIMKLGDGLFLRSCEEVSRL-YPRIQFEKMIVDNTTMQMVSNPNQFDVMVTPNLYGAIVDNLASGLVGGAGVVAGASYSSESVVFEPGARHTFAEAVGKNVANPTAMLLCGVKLLRHINLPTYGEIIQNAINKVLNDGKVRTKDLGGQSTTQDFTRAIILNMS---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28834-1", "uniprot_id": "IDH1_YEAST", "id": "P28834-1", "name": "Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial", "aln": "---------------------MLNRTIAKRTLATAAQAER--------TLPKKYGGRFTVTLIPGD-GVGKEITDSVRTIFEAENIPIDWETINIKQT---DHKEGVYEAVESLKRNKIGLKGLWHTP--ADQTGHGSLNVALRKQLDIYANVALFKSLKGVKTRIPDIDLIVIRENTEGEFSGLEHESVPGVVESLKVMTRPKTERIARFAFDFAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIGQKEYPDIDVSSIIVDNASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRDYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLNHLGLNEYATRISKAVHETIAEGKHTTRDIGGSSSTTDFTNEIINKLSTM-------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A1ZAD2-1", "uniprot_id": "A1ZAD2_DROME", "id": "A1ZAD2-1", "name": "Isopropylmalate dehydrogenase-like domain-containing protein", "aln": "----MLRCPKVTQSMLARISVRHFADEIHGSVRAAYAKGDARADPVNVLPKSKYGGINTVSLVTGTTIIGQQGAQFVSSLLSSSRVPVEVQVIEAGQD---------DEYFHSVLRNRTAVHVDNQAD-----AEAKQKALKICNDLDLYVFKTRTRSFPGFKCRFPGVDIQLIGQNNMGIFNELEYSPVEGVVEALSVVSQKGNDKYLRYAFKAAAKAGRKRVTLINKAKEWPISDGSLVEAAQRLHCHYKDCLELELMEVEEAISRLMTEPTYFDCLFASERYATFLSAICSGVCGGANLFSAVEIGDHHAVFKP--LQTKLSLTNYANLSAYGIVSTIVDLFQHLGHDKCADALWCELKRTMDEG-IRTKEFGGQDTGEYVICNIINQLRCRALGK---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :::.* :* : : :: :*:: : . : . :: .* : : : **::. ::: * * .:* :: ::. * :. **:... *::*.*.::: . : :** * : * ** ::**: :.** : . : : .. : ::: : : .* ** :. .. *. .:. : :.: **..:... . . .:*: . . .. . : :: :: . : : : * ::** .. :: : ", "identical_positions": 35, "similar_positions": 115, "identity": "8.58%" }, { "cls_id": "homologset.agr.SGD:S000004983", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14442-1", "uniprot_id": "PIGH_HUMAN", "id": "Q14442-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit H", "aln": "-------MEDERSFS---------------------DICGGRLALQRRYYSPSCREFCLSCPRLSLRSLTAVTCTVWLAAYG--LFTLCENSMILSAAIFITLLGLLGYLHFVKIDQETLLIIDSLGIQMTSSYASGKES----------------TTFIEMGKVKDIVINEAIYM-QKVIYYLCILLKDPVEPHGISQVVPVFQSAKPRLDCLIEVYRSCQEILAHQKATSTSP------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A0Z0-1", "uniprot_id": "D4A0Z0_RAT", "id": "D4A0Z0-1", "name": "", "aln": "-------MEDEKSFS---------------------DICGGRLALRRRYYSPYCREFGLSSARLSLWSLTAVTCTVWLAAYG--LFTLCENSMILSAAIFITILGLLGYLHFVKIDQETLLIIDSLGIQMTSSYASGKES----------------TTFIEMNKVKDIIINEAIYM-QKVIYYLCILLKDPGKPHEISQVVPVFQSAKPRLDCLIEIYRSCQEILAHQKATPTSL------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5M9N4-1", "uniprot_id": "PIGH_MOUSE", "id": "Q5M9N4-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit H", "aln": "-------MEDEKSFS---------------------DICGGRLALRCRYYSPYCREFGLSSARLSLCSLTAVTCAVWLAAYG--LFTLCENSMVLSATIFITILGLLGYLHFVKIDQETLLIIDSLGIQMTSSYASGKES----------------TTFIEMDKVKDIIINEAIYM-QKVIYYLCILLKEPGKPHEISRVVPVFQSAKPRLDCLIEVYRSCQEVLAHQKATATSL------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VHX6-1", "uniprot_id": "Q9VHX6_DROME", "id": "Q9VHX6-1", "name": "", "aln": "-------MEPKVTIHRYYSRQAKYEGAVEADLELCIKHCGGDVVRIELVNRLHGIQLQRKLRRLLLLMFLSIAYFVGTCGFDNRTISFLQPRILYPLITCASVAILLIRSTLNLVQAERLFYSWDMALQMETVRSFGRES----------------VLCVQRGHIEDIVLNEVIED-LDVKYMLILRTK--GSQFKKRPIIPLFNSQSPSIECLQHTYHVLHKYWLNSTKDRSEESYSKDKQSLVNS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53961-1", "uniprot_id": "GPI15_YEAST", "id": "P53961-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI15", "aln": "MISKEYEFGKTSILNRKKYTLVIDEDKNGNFIRFTVLPVSNRKFKKVKQNGRVEINMGIQYHQIVLILLLNILFYVICLRSR--FLEHINRTFEVTIARSFQILIIMGLFALGTIILVRGPSVETVTIFKESGLQLSRVKGMVIFPQQWNRKFFEQVEFISNERIIDVVINEGFCRGFRVIFYLAAIVR------KSSTLKLLFPSNLPSIDDQRLIYNISRKYLSKQEKPLSRPKD----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .. :: . :: * : : * : : : . : :: : : : : : .: . . :. :: *:::** : * : * : : :* * * :: *. :: :. : ", "identical_positions": 11, "similar_positions": 47, "identity": "4.45%" }, { "cls_id": "homologset.agr.SGD:S000004984", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LUC8-1", "uniprot_id": "A0ABK0LUC8_RAT", "id": "A0ABK0LUC8-1", "name": "", "aln": "MKRRRWRESGGGGGGAKLRARLSVKPNVRPGVGTRGSAAPNPQRGPEAPRPPEPATGSAPKPAEPTDVPAVDSGGAEPQEQAPGSSNNEKTGDGSNVEESSTLPSAASQRRKRVSGTSSLGQPPVSAPSQSRPLSTVNHDAPQPNPTPAKEKQPCSDRYRIYKARKLREMLKEELRKEKKQWKNKFATNESQRPPDRSKMTMRDFIYYLPDSNPMTSSVEQEKKCEKSLAPTPTRE-QENQSTQDANDNEDVEEEVDDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGSTTTYSSFRKNYYSKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKAFQEKRPFDFDFFAHLLQKVLAEEEKRKQKSTKCQNVKEKAP-KPRKNAKAKTVNREEVNDDPDESVNSDTADPERPQKDARTVREEQLPSSSAQHLHLAVLEQEQEQEQSQDKRRRNQGKANKREATTVLESVLDHSSPPAAEIHKSTCPSEE---NENECNKEQTPSFTQNTEDIAGLASCEETLMRMDPSPSTCNHQDIMPLASESSEPCAADLPVSEPGGAVSGDVNNAESGCAGAGSADLKTKSPETEQTDSVKPKSRSRLQRPKPNLSRPVGKKSVVSQDRQDGSNKDSPSETAATKNHMEKERVTESENFVTENTERESPSAGTVSDLSEKSSAQEDSQTKVLRPTRLMRSRMQRPKPNVVKAAERKQILTSQEKVGSHVEKIEDDSCVV--VPPQMGNESHKNLQCEGAASEPEQKDPVESLQSEQPRALSECPSIQEDNKGNKLKQAPIVRTRFQKPKPNTGR-RRRRRRSSKEGIPVDMPVSGDLTATREEIPRPDTSPREEVPSVP----------------LAP----LTATASTMELESGVKDSSRNDTASNVKMPEMADVTMEIDTGLETTG-RDTCPGEMEAEMIDIPMETEASLKASLNETPPMEKMPELIDNTGEICTNLGETARKEIFLQENGSKEVSPVSEPETGLQETG----------------------------------------------------------------------------------------------------------KKLAVKESTSDMMDGTEEREADSEETERQE-ISAPVKEAEEAKARGEVDSPLEEIGGETSQQA-----IAAGAPVEQSASEEDLGDS--------------------------AGVEEVEVESTVG-GKELKLKDAGEGHVSLMVVVSGEKTAIEETIGHLKEKERESSVPWERRSGEIDVGEEMVADLEKTEKVDVSPRDSEPEEQ-TSGQPEAEVIPSRS-DGSTGPPQDRENIS-NKISVIPTLLEEKETTDKEVSSHG---ESSSQNS-GHHVADQGTQLLDVQEQFSDTNLSKPLPQEQKPLQVKPAPFLRSRFKKPKPNLSRAALKRATLEAEHCVPGKKPEAYKMETVVLQQDRDQAASFSSPHNVPSLMASRENEKSGHEEEEEAVVLPCTQIEKDPSPPNSCEPKEDSQLTQNQEDSLVSPIGTPTVNMVPQETKPNVVQTTLPVRGRLQRPRPNVQKARQRQTVEKGKAEGITKNEGPELQKDEAKTCLTVANSSGVESEVAVEVSSRVSEFKVNESQGHVVPVENLSINKTSVLREQIRHENKPYVPSPALLIRRRFQKAKPNLGGARHKDEQPGVEKGPTSENTALTTEDHLLQKGDCDTQLSVQAREKTEMPLEVSMRKDCVHSEESGSDRNDAQLK-AGPSGGAREEIAQEPTFSSSLEEQSLSKQISR--PQLLKESSYSKTVPPRRTTVPSASECEIDHSGKRAHRKMKASVTKARGSKRIRGKTAKKEPRASKSVLVTLRASQKDDEDDAEDFESDYEEETCHLAPEELNKAPVFVPVGLRSPEPVSAQIEETMEELEITMDGADLGCLTVVDHQLSHVDIAARDEQPEKAVYPSSFEVVIGEQPQEEPGPGDGSTEAAITLLTMGDIVLQSEIIPGQGDVGVCVFPDDHSKDKNHVPFIPDNVNQKTVHDYQEVCSPVISMSHVSFEDNKIVLEEQSIRE-AAVLGEAMEEPLSTRDTACTMSTPLRMESMLVTPKAGSERILEISEPDGHQEVASLCMTKGTEVEIQRETEENDSTAVELDDKSLEPVPAAETKEQEQLLCVHGVEGARVSQEAILPARTEEHEDDLQGLQTLGAA-VASSEIGQHTLESGQSLGDSVAEEALRESPEGSVVPMLHVPESVPSNIPEAQHENIS-PQDDTVNLFANVQQDGEDEQAFILTLVEIPTNTTEGFTDASMHLMPSSLLPAPILVRSGNAVERVDLSGSLQASSVVQDVTCSSPSRSGDSEKPPAIVELTSRKRFCCSPDESIHVPPAKKSSIAPGIDYQNCTSGVCSEELN-VFEKTEESCMGQGIFPTSESTHATSKPQKEHSEQTSQNTGSSGSLGEIKDACVENTMTELPQSE-VVSDKEEKTDPASNSKQRDSVTSSSKPPLTRPGRRPLGFLSLICPKNSLESDEVTQTHSKKRLKPHIPVSRRNLKKPNPLHASQKKNQESSDPLPPPSVTETVSDNTGSSESSAAEVSSDQPLVEEEKCKNGPKGASEEEVTTVSEFVFSDIFIEVDETE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q571C7-1", "uniprot_id": "BDP1_MOUSE", "id": "Q571C7-1", "name": "Transcription factor TFIIIB component B'' homolog", "aln": "MFRR---------------ARLSVKPNVRPGVGTRGSAAPNPQRGPEAPRPPEPATESAPKPAEPTDVPAVDSGGAEPQEQAPGSSD-EKTGDKNNAAESSTLSSASSQRRKRVSSTSSLVQPSGSAPSQSRPLSTVDHDAPQPNPTPAKEKQPCSDRYRIYKARKLREMLKEELRKEKKQWKNKFSTNESQRPPDRSKMTMRDFIYYLPDNNPMTSSVEQEKKPEKSLAPTPTRDRQENQSTQDANDNEDVEEEVDDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGSTTTYSSFRKNYYSKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKAFQEKRPFDFDFFAHLLQKVLAEEEKRKQKSTKCQSLKEKAS-KPRKNLKAKTVTSEEVNDDPDESVNSNISDPERSQNDAETVNEEESPSSSGQHLEQAMLEQDQNQEK---KRRRNQGEANKQEATNLLERVLVHSSPPAAEIHKNTCPSEE---NESECNKEQIPSLTQNIDDIAGLAPSEETEMRMDPIPSTCNQQDIMPLARESSESCAVALPVWEPGNTASADMAHAESSCSEGRGADLKTAAPETEQTENVKPKSRSRLQRPKPNLARAVGKKSAVSQDRQDERNKNSPSETAAEKNHMEKETMNESETSVAKNTDGESPGAKTVSDLSEKSCVQQDSQAKVLRPTRLMRSRMQRPKPNVVKAAERKEILTSQEKFGAHVEKSEDESCVV--IPPQTENESHKNLQCEDTVSEPGRKDPFENIQPDQPQVLSDCPSIHEGNKENKRKQVPVLRTRFQKPKPNTGR-RRRR-ISSKEGIPEETPISGEIPATWEEIPSLDTSLREEVLSVP----------------LAP----LTATASTKDSESDVKDSGRNDTASNAEMSEMTDVTMEMETGLETIG-RDTCPGEMGAEMIDIPMETEAGLKASLNETSCMEKVPELIDTTGEICTNLGETGRKEVFLQENGPKEVGPVSEPETGLQETG----------------------------------------------------------------------------------------------------------KDLAMKESTPDTTDSTEEREAYSEETERQEKISALIKDAEEAKARGEMETPLEEIGGGTSQRG-----KAAGAPVEQSASEEEPQGS--------------------------ACREEVAVESSTAEGKELNLRETGEDDVSSMVVVLGEKTDIEETNGDPKETERESSVSWERGSGEIQVGEEMVEDLGKPEKIDVAPREREPEEH-SSGQPEADVILSSS-DGSTGSPQDKVNIS-SKISVMPTLVEEKETTDKDISSHLGHVESCSQNL-GRHETDQGMPLPDALERFSDTNLSKPLPQEQQPLQVKPAPFLRSRFKKPKPNLSRAALKRATIEAEHCVPGKKSEACKVEAAMLQQDSDQAA-LSPQHNVPSLMASRENDKSGHEEEEEAAILPCTQTEKDASPPNSSEPKEGSQLTPNQENGLLVPIGTPMMNTVTQETRQNVVQTTLPVRGRLQRPRPNVQKARQRQIVEKGEARDIAKNEGPELQKDETRTCLTVANSSHIESGVAVDMSSRVSECQVSESQGHADPVENLSVNKASVVHEQMRHENKPYVPSPALLIRRRFQKAKPNLGGARRKDEQPGVEKGRTDESTALTAEDHLLQKEDCDTQLSLQAREKADMPLEVSVRKECIHSEESGSDRNDAQPN-AGPSEGSRDETAKEQPTSLGLEEQSLSKQIRSSCPQLWKESSYPKTVSSRRTPLSSASECEIEHSWKRTQRKTKPNLTKGRGSKRIRGKTAKKEPRASKSVLVTLRASQKEDEDDAEDFDSDYEEETYHLAPEELSKAPVFVPVGLRSPEPVSAQIEETMEELEITMDVADM---TVVEHQLSHMDTTAQAVQAEKAVYPPSFEMDVGEQTQEEPGPSDGSTEAAITLLTMGDIVLQSEIIPGQGDVGVCVFPDVHSEDKSHAPFSPDNVNQKVVHDYPEVCSPVISTSHASFEENRIVSKEQSNRD-AAVEEEAVEETLPTRNTTSTMSTHLRMESMVVTPELNSEKTLEISESHGHQEVASFCITKETEVEIQRETEGDDSKAVELEDKSHAPVTAAETKEEEQSQCVGDVEGASVSQEAILPARIEDHEETLQEVQESGTA-VASSEIGQQTLDSGQSFGESAAKEALKETPKGSDVPVLHGPESVPSHIPEAQQENTG-PQAVTVNPFADGQQDGEDEQAFILTLVEIPTHATEGFTDAAMQLMPSSLLPAPILVRSGNAAERGDLSGSLQTSLVVQDAPSLSPSRSGSSEKPPANLDLTSRKRFCCSPDESIHVPPAKKSSLVPGIDYQECTSEVCSEELN-VFEKTAESCMGQGIFPTSESTHATSKPQKEHSEPT--DTGSSGSLDEIKDACVEN-MAQLPQSE-IVSDKEEKTEPASNSEQRDIVTSSSKPPLTRPGRRPLGFLSLLCPKNSLESDEVTQTHSKKRLKPQIPVSRRNLRKPNLHNTSQKKNQDSSAPPPSPSVTAPLSGTAGSPESSAAQVSSDQPLLKEE-CKNGPKGAPEEEVTPVSEFVFSDIFIEVDETL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6H8Y1-1", "uniprot_id": "BDP1_HUMAN", "id": "A6H8Y1-1", "name": "Transcription factor TFIIIB component B'' homolog", "aln": "MFRR---------------ARLSVKPNVRPGVGARGSTASNPQRGRESPRPPDPATDSASKPAEPTDVPTVDFGGAEPQEKAPRSST-EKTGGDNDVEESSRSSSTVSQRRKRISSTSSLVKSSVSVPSESHPLSTINQEAPQPTATSTKEKQPCSDRYRIYKAQKLREMLKEELRKEKKQWKNKYAINESQRPPDRSKMTMRDFIYYLPDNNPMTSSLEQEKKTEKPSTPVQTRE-QEGKSTPNAEDNE-MEEETDDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGSTTTYSSFRKNYYSKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKAFQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNHSLKEKKSTKPRKNVKVKKVACEGVNNDPDESMSSRISDTERSQKDAQTVEEESLTLSR-EDAEQVALEVDLNQKK---RRRKKQDGANELGVNNLLENATVQAGPSKGEKHKNKCQAIRPELKEGECSKEQMLSCTQNIDGIVGFASTEKVEKRTDPILSLSNQQDATSVATESSESSTSDLPSFEVGIRALCEVNNAEGSCIEERNVDLKNNSLEIDQTENVKPMLRGRFQRPKPNLSR-AGKKSVLSQGKTESESKNSHSKTSVEKNHVEKDKMNTLDILRMETTERENPEAETVSVLGEKNCLQEGSQLKALRP-VQVRGRLQKPKPNAGKAAERKEILISQEEIGANVEKNENESCADRDTPQHMEDQSRKDFEEEDVILQPEKNDSFQNVQPDEPKVLNECLSVQENNKANKLNQVPILRTRFQKPKPNIGRGTGRREISSKEEVLEKILVSGEMAAALRETVRLDTSPKEMVPAEINTKEMQSDLKETGRRAISPREKILDVIDDTIEMETGLKAMGR-EICLREKTPEVIDATEEIDKDLEEAGRREISPQKNGPEEVKPLGEVETDLKATGNESSPREKTPEVTDATEEIDKNLEETGRRKISPRENGPEEVKPVDEMETDLNATGRESSPREKTPEVIDATEEIDLEETEREVSPQENGLEEVKPLGEMETDLKATGRDSFPRGKTPEVIDAIEEIEIDLEETEREISPQENGLEEVKPLGEMQTDLKATGREISPREKTPEVIDATEEIDKDLEETGRRE-ISPEENGPEEVKPVDEMETDLKTTGREGSSREKTREVIDAAEVIETDLEETEREISPQENGPEEVKPVGKMETDLKEIREEISQREKVLAEFSAIREKEIDLKETGKRDIPIMEKVSGKMAVVEEMEADLKETGKEN--FRERGSEEICVTEEKVAELKQTGKTDISPRENELEETSTSRQTDTHLMQSGSNDFSAVPSLDIQNISSEVLSMMHTPVEEKRNSEKEVSSHFSHFKISSQTHESDKTEVQGIQSPDVPEQFSDINLSKSLPQEQKPLEIKPAPFVRSRFKRPKPNLARAALKRETTESEKYIYEKKSETKKMETIVMQENNEQTDTLPSQHDEASLMISREKDTLGHRNEE-AVILPCTQTERNLSPSNSCEPKEESQSAPVQKNDSVVSVGTNNVNTFQQEMKESVIQTARQVRGRLQRPRPNIRKTGQRQIVDKGEAKGIIKEGRTILPKDETEKKVLTVSNSQIETEIEVP-SSAVPEHRMYENQSQVVLVENLHVNKT---NETIRHENKPYVPSSAQMTRRKFQKAKPNLGRAHSKKEEPVLEKVTTDQSKEGKPEDHLLQKGASNTQLLLKEKAELLTSLEVSARKDCVGSKESALAKIDAELEEVGPSRRVGEETVGDNSPSSVVEEQYLNKLTSC--PQPLNETSYSKIALDGKTTISSTSEYERNRGERRSHKKFKPNVTRGRGSKRVRGKTSKKEPRASKAMLVTLRASQEED-DDADDFESDYEEESYHLAPEEVNKAPVFVPVGLRSPEPVSAQIEETMEELEITVNVPDVGCIAVVEHELPNTDVTTEEMKQEENLSVP-FEMTTSEHIQDEPGTNDGSTEAAITLLTMGDLVLQSEISSEQGDVGVCIIPHVHSKDKSHIPSSLDNVNHKIVHECQELSSPVITTSPASFEENKIVLEEQSSREEISLMEKVKENATPTRNTISKVTSNLRIRSRLAKPKPNLEKTLGTNRLDDYQEVSSLCVTKGAEMETQRETEKNASKATELENKNLGPVTTAENKDQSKLACVHGIKGTSISSEVNLTERNENQEESSQEVHMLSVAPVASSETGPCTLGLDRGLGENSVEEPQIKDSKGDSVLTLPVPEYTPTSIPEVQQENIINPQDLTVNLVANVPQDGEDEQAFILTLVEIPANAVEEFTDATAQFMPNPLLPAPILVKSVNTEERGDMSICLPATSVGQDAMGLSISGRDNSKKPPDNLDLVSRKRFQCRLDKNDHIPPAKKRSLTLRDDCQEYTTEVHSKELTNVFEETGESHKGQDIFLTSGSTLTTPEPQRQQVEAAFQSRGSRS-----PDACMDKNVPQLPQDEMIVSDKEERTDAAPKSQQMDSRTSSSKASLSRPGRRPLGFLSLICSKNSLESDEPMQVHSKKRLKPLIPGLRKKLKRSNPFNESQEKNRESSDLLPSPSVITTQSENIS---SSATQVSCDQPLLKEG-YKSAQKRAPQGEATTVSEYFFNDIFIEVDETE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YV30-1", "uniprot_id": "A0A8M6YV30_DANRE", "id": "A0A8M6YV30-1", "name": "", "aln": "MMRR---------------SRISVRPNVKP-----TGRAPTASREASAENAQAFQSPADSAPSEGSEVTAEKLN-TDPSIAAPEQTN----------EDASQSSSPSDQLEDTRRGEDASSKSSNALDSVSTSVTSGPQRRKRFTALPNLAKPRASQVSAKTPKSPIKSPVKPVTPIE----------------PEKS-----------TTNADIPAPVHNPRVPARRRPSGGSRP-AKSQLIPPESLQKDGESQKNGGLLEVVVPLTVQEGGVGTISPPDTVSDVNENRPTPPTVEEMVVQQESDS----------GAPPDQSQTDLLKEKLKKLKSTSKIIKSLTAVNDPADMIRLAQARKLR---------------------ELLKKEMVKDKEDKRK--LKMGLKERKAPKDHTKMTMRDLIYYLPVSNPMKSFT------EEEQKASETVLDDSPTPIS----------------------------SNTPDPPAVEEPVVEDADPEEDEERTEEAQEED---------KEPLLVPRVKVAEDGSLIIDEESLT-------------VQVLRANGPNPAEDRDPIFERG---------------------STTTYSSFRKGTYTKPWSNGETEMFFLAISMVGTDFSMIG-------QLFPHRGRLEIKNKFKKEEKNNAWRIDKAFKEKRRLDLDFFKKLMEQILNDEEE-------------KKNKSKEHFKLAKAKRKVRVAKRKGMDSSEDSDSDVVAG-----EKENEDLSNDGESDVTPKRRRGRAAKNTDRDIKRIYEEVDNPEDCENVTSDTQSPDDRLKDSESSKNINK--------------------------------------------------------------------------------------------------------------------------------------SPSIKPALLKGRPQKLIPNISRRWGERRP------KNNIQENRTSAKDEDPLKVP-------------------------------------------------------------------------------------------------------------------------------------SASKEEKDKKQ--ASVIIDLIDLDEEPDLS----------------------------------------------------------------------------AVQEQIFNKPTRSGRIPKLSQHVIQAAAEEEEDE-------------EEPSDPPTSSKVCVPSPGCRAKIKPGPRLKQGMQRRGKSR---------------------------LVTLLASGAEEDDDEER----------------------EEAEGCILSQEDFPSN--SEEENQAFVPMSLRPQDHFDSEVVETMEELDISANVPDILSASHNALCPES--------ACEQAVFPAGPVSYEHQLDLLVDVIEFLDPEHMEVCKEINNEAAQTLLTIGNSAQMIQTSEMPCLSGHDIDVHEEIANEEVFTETAIMSDPSISCYSEMR--------------------------------------------SDVELSNSETQIPEPPTSIEEPIKSQNSMSHPGPVQQVSQDLAS-----------TFVPS---STRGRFAKPKPNIG---------------------------------------LKSRRAPQQQISSELPADSVENSKSLTSAEQDEKQ-----KASMQEIADELSDSSNIHP----------------EVQQPGTVSDRREDAPERLTGGDSGSAVSLKRKDEDEIT--------EEKIKEHEEAKSDPVLINSESE---------------SQSTLDEAPKPVRRN--------RGPKPK------------------------------PNLTQASRKKHTQTQLNTPSLTTGITFTKSPEEGAVITTEPDVSQRATQQEVTLRLESTQAVKDISPVVSEDNSRPN-----------TLVRLDEEQNITAPDEAFEDSSVKHSRCESKDASEES---------MFILSLTEIPPALQQGACLRTEPLPPTIEPGLHSHGQSVNESKEVSHLLLTDALVLVSEEEEKEGEEEDKSRRGQLKRKTPASTSQESTKSESQAEDCVVEVSESPVAEETDEHLEK----------------------------------KRKPPERTRRAKLQVKPIP-------------------------VMRKNTRGVKEDTAALTLKETPSLPISTAETKPEQTDPTVISTS----------------------------------------------------------ASSDNIPSSEES----------------------VQEESSQGTVG--------------------------------------------------QVDITVKETDELASGSDSQTATQITPVATSGPLTRPGRKPKGFLSFISTKSTQG-----APTRHRGSKPGVNTARPDRKQ----VASASANLGVKRALPTPASTTEQR--------------------------------SEEEPTSVSKYFFSDIFTEVDELEDMD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJZ3-1", "uniprot_id": "Q9VJZ3_DROME", "id": "Q9VJZ3-1", "name": "", "aln": "---------------------MSMRR---------QRIKAPANLSLIKRKPRREELPTAKKEDEEEEAVVVEAEAESPPVAS---------------TPAAELELEADAIAFKMPASSAGQLEEVFHSDLEDNVIQMDLQKTTNGFPMSPSKAQARQRVRPTPVFGQRR------------------------------------------NSFVGSPMASDYEGDYQSPATPTRR---ERYLSGSSSGTPLQQQVHSPMPPSPYKYLP--------PASPGMGRIRTESTCSTYSEGGSKQRKGDD------------------------------RSQSQIGQRLNARRDFETR------------------------------------------------------FNKGVPDKSTFKMMDMIFYNPENNP-----------MVPKQSVTTIKDES---------------------------------------------GGDDSKPAVSQLLEPKGESTS-----------AMLVPQLKLDANGEMIIDEKTLE-------------IETTAEVEARKVLANSSLILMD--------------------ETTGDNGFYKRHKRTPYWTSDETVRFYRSLQIIGTDFSLMC-------QMFPTRSRRDLKLKYKKEERTNGQLINKALLYPKAFNIQELKDQLEEEDR-------------------------------------------------------------EREENDRKWREIARALPGNPKKRSRVQQQSKASRALNDGDVVYENEHVTSTKLGKHAWAKR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RKELETDENDG----------------------------------------------------------------------------------------------------------------------------------------------SAPAKRKPKAK-------------------------------------------------------------------------------------------------------RRSPKVSVPAATESLSDVAAIK--------------------------QEKTIKTEQTSSHLPTG---------------------------------------------------------------------------------------------------GELQAELNGLLMDDPVEYDVDVNKPRD--------KTIINMDDGTLSYVS------------DVEPAPETPNRKAETYLINFIE--DQDHELITPDDPIPPSTTEPDIEQILAELAEGSLALVSSLDPEHEDRVLNEIYMLDKKTG-----------------------------------------------------------ELCETPLKIPEHIVQCIMNVMQPED---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46678-1", "uniprot_id": "TFC5_YEAST", "id": "P46678-1", "name": "Transcription factor TFIIIB component B''", "aln": "------------------MSSIVNKSGTRFAPKVRQRRAATGGTPTPKPRTPQLFIPESKEIEEDNSDNDKGVDENETAIVE-----------------KPSLVGERSLEGFTLTGTNGHDNEIGDEGPIDASTQNPKADVIEDNVTLKPAPLQTHRDQKVPRSSRLASLSK---------------------------------------DNESRPSFKPSFLDSSSNSNGTARRLSTISNKLPKKIRLGSITENDMNLKTFKRHRVLGKPSSAKKPAGAHRISIVSKISPPTAMTDSLDRNEFSS-----------------ETSTSREADENENYVISKVKDIPKKVRDGESAKYFIDEE--------------------------------------------NFTMAELCKPNFPIGQISENFEKSKMAKKAKLEKRRHLRELRMRARQEFKPLHSLTKE------------------------------------EQEEEEEKRKEERDKLLNADIPESD---------RKAHTAIQLKLNPDGTMAIDEETMVVDR---------HKNASIENEYKEKVDENPFANLY------------------------NYGSYGRGSYTDPWTVEEMIKFYKALSMWGTDFNLIS-------QLYPYRSRKQVKAKFVNEEKKRPILIELALRSKLPPNFDEYCCEIKKNIG------------------------------------------------------------------TVADFNEKLIELQNEHKHHMKEIEEAKNTAKEEDQTAQRLNDANLNKKGS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGIMTN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DLKVYRKTEVVLGTIDDLKRKKLKERN-----------------------NDDNEDNEGSEEEPEIDQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . .. * . .. . . . .. . . ... . :* . : . : : . .. . : . : . . . . : : : *: . . : . . : . . : . . * : :: . :: : . : .: :. . . : : . : . : . . ", "identical_positions": 4, "similar_positions": 74, "identity": "0.15%" }, { "cls_id": "homologset.agr.SGD:S000004985", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI97-1", "uniprot_id": "AASD1_RAT", "id": "Q5XI97-1", "name": "Alanyl-tRNA editing protein Aarsd1", "aln": "----------MAFLCQRDSYARE-FTTTVVSCCPAELQTDGNGSKKEVLSGFQVVLEDTLLFPEGGGQPDDR------------GTINDISVLRVTRRGAQADHFTQTP--LSPGSQVQVRVDWERRFDHMQQHSGQHLITAVADLLFGLKTTSWELGKLRC-----------VIELDSPSVTA-EQVAAIEQSVNQKIRDRLPVSVRELSLD-DPEVEQVRG-RGLPDDH---AGPIRVVTIEGVDSNMCCGTHVNNLSDLQVIKILGTE-KGKKNKSNLIFLAGNRVLKWMERSHGSEKALTSLLKCGAEDHVEAVKKLQNATKLLQKNNLNLLRDLAVHTAHTLRSSP--AWGGVVTLHRKEG-DSEFMNIIANEIGS---EETLLFLTVGD-----EKGAGLFLLAGPTEAVETLGPRVAEVLE---GKGAGKKGRFQGKATKMSRRAEVQALLQDYV-------------STQSAEE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3THG9-1", "uniprot_id": "AASD1_MOUSE", "id": "Q3THG9-1", "name": "Alanyl-tRNA editing protein Aarsd1", "aln": "----------MAFLCQRDSYARE-FTTTVVSCSPAELQTDASGGKKEVLSGFHVVLEDTLLFPEGGGQPDDR------------GTINDISVLRVTRRGAQADHFTESP--LSPGSQVQVRVDWERRFDHMQQHSGQHLITAVADLLFGLKTTSWELGRLRS-----------VIELDSPSVTA-EQVAAIEQSVNQKIRDRLPVSVRELSLD-DPEVEQVRG-RGLPDDH---AGPIRVVTIEGVDSNMCCGTHVSNLSDLQVIKILGTE-KGKKNKSNLIFLAGNRVLKWMERSHGSEKALTSLLKCGVEDHVEAVKKLQNATKLLQKNNLNLLRDLAVHTAHSLRSSP--AWGGVVTLHRKEG-DSEFMNIIANEIGS---EETLLFLTVGD-----EKGAGLFLLAGPAEAVETLGPRVAEVLE---GKGAGKKGRFQGKATKMSRRAEAQALLQDYV-------------STQSAEE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BTE6-1", "uniprot_id": "AASD1_HUMAN", "id": "Q9BTE6-1", "name": "Alanyl-tRNA editing protein Aarsd1", "aln": "----------MAFWCQRDSYARE-FTTTVVSCCPAELQTEGSNGKKEVLSGFQVVLEDTVLFPEGGGQPDDR------------GTINDISVLRVTRRGEQADHFTQTP--LDPGSQVLVRVDWERRFDHMQQHSGQHLITAVADHLFKLKTTSWELGRFRS-----------AIELDTPSMTA-EQVAAIEQSVNEKIRDRLPVNVRELSLD-DPEVEQVSG-RGLPDDH---AGPIRVVNIEGVDSNMCCGTHVSNLSDLQVIKILGTE-KGKKNRTNLIFLSGNRVLKWMERSHGTEKALTALLKCGAEDHVEAVKKLQNSTKILQKNNLNLLRDLAVHIAHSLRNSP--DWGGVVILHRKEG-DSEFMNIIANEIGS---EETLLFLTVGD-----EKGGGLFLLAGPPASVETLGPRVAEVLE---GKGAGKKGRFQGKATKMSRRMEAQALLQDYI-------------STQSAKE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DEJ5-1", "uniprot_id": "AASD1_DANRE", "id": "Q6DEJ5-1", "name": "Alanyl-tRNA editing protein Aarsd1", "aln": "----------MAFQCQRDCYMQE-FDSCVVSCVPAELKLE-NNGRKEKLTGFNVKLKDTILFPEGGGQPDDH------------GTIGGVPVLRVLRQGPDAVHFVSSA--LEEGQEVHIKLDWERRFDHMQQHSGQHLITALADTMFGYKTTSWDLGRQRS-----------SIELDTATVKP-GEMEALETAVNEKIRAHVPVTVNLLSID-DPAVEKVRS-RGLPDDH---AGPIRIIDIEGVDANMCCGTHVSNLSHLQVIKILGTE-KGKKNKTNLIFIAGNRVLKYAEKSYNIEKSLTVLLKTGADEHVDAVDKLQKTVKRLQKSNLTILREMAVLIAQNFKSKP--DRGHFFSLHNKDG-DNEFMNIVANEIGF---QDTLIFMTVGD-----EKGAGLFLIAGPENIVTEVGPRVSELLQ---GKGAGKAGRYQGKANSLVKRAEVEALLKERS-------------YKCTAGDE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4R9-1", "uniprot_id": "Q9W4R9_DROME", "id": "Q9W4R9-1", "name": "Alanyl-transfer RNA synthetases family profile domain-containing protein", "aln": "----------MVFKCQEDSFLKE-FKTKIVSSEFATLDWTDPSGKVEKLKGFNVICEDTILFPEGGGQPCDY------------GTLGGFPVKNVQRKGSTAVHFVESPTSFEQDAEVLLTLDYQRRLDHMQQHSGQHLITALFDREFKYDTTSWSLGSTVS-----------YIQLSTPHLISRESLDLIERQANDLIREGREVTVLLVDPEVAQEFQDARAPRGLPKDH---EGLARVVRIEGIESNMCCGTHVTNLSQLQCIKLLYAE-KVKAN-VLVHFVVGERVLVKLGEVFQREQQLTQALKGGPGQHLELVQKLQQNVKGSRKYFQQLLKRYATAEAERLCDLPKKDRPKYFSLHRRDGIEVDFINTFLRAAP----EGIFYFLTVSESVFAGSSAKGHLVLRGDPEIVGKLGPQFMEILE---GKGNGKEDNFQGKINNLARLQECQELLEAEFKPKRIIEAAPANGAQLEAEE-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53960-1", "uniprot_id": "YNE0_YEAST", "id": "P53960-1", "name": "Putative alanyl-tRNA editing protein alaX", "aln": "MPTPMTPVKVGALACQRNSFLFDGFKTLVVSCEPTK-------NKKGEIEGYEIELQDTILFPEGGGQPSDSGFLKIVEGNRNSSKIEKILVSHVSRFGLHAKHHVNDY--IEPGTTVEVAVDEQKRMDYMQQHTGQHLLSAILERNYKVDTVSWSMGGIITKKKPVLEPSDYFNYIELNRKLTLDEITNVSDEINQLIINFPQEIIVEERIG-EETVDEVST-SKIPDDYDLSKGVLRTIHIGDIDSNPCCGTHLKCTSQIGSILILSNQSAVRGSNSRLYFMCGKRVSLYAKSVNKILLDSKNLLSCSETQISEKITRQTKQIQQLNKREQYWIKRLARTASEELMNTLKASGKKRAYFMEEEYGTLELLLQIHKEVSNFLKDDTEGYEIILCGYERQTNTGSLLILSESGEKIANLAANLGSILQNLKGGGGKKGGKWQGKITSISN-AEFAALSDYLS-------------HDFASC--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: **.:.: : * : :**. : .: : *:.: :**:********* * ..: . * .* * * * *... :. . * : :* ::*:*:****:****::*: : : .*.**.:* :. . .: :. *: * : .:.. :*.*: * * : * .:::* *****:. *.: * :* : : . : *: *:** . *. . : : : : : : .* :: * :. : . : ..: ::: . . : : : . . ::: : :.... .:*: * * * ..:*** ..: . * * . : ", "identical_positions": 73, "similar_positions": 129, "identity": "15.11%" }, { "cls_id": "homologset.agr.SGD:S000004986", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68FP9-1", "uniprot_id": "COG6_RAT", "id": "Q68FP9-1", "name": "Conserved oligomeric Golgi complex subunit 6", "aln": "-----------------------------------------------------------------------------------------------------------MADTSGEVAAVPASGAANGLSNGAGATPAQPNNPLSRKLHKILETRLENDKEMLEALKALSAFFVENSLRT-----------------RRNLRGDIERRSLAINEEFVSIFKDVKEELESINEDVQAMSSCCQDMTSRLQAAKEQTQDLIVKTTKLQAENQRLEIRAQVADAFLSKFQLTSDEMTLLRG-TRGGPVTEDFFKALGRVKQIHNDVKVLLRTNQQTAGLEIMEQMALLQETAYERLYRWAQSECRALTQES----------CDVSAVLTQAMEALQDRPVLYKYTLDEFGTARRSTVVRGFIDALTRGGPGGTPRPIEMHSHDPLRYVGDMLAWLHQATASEKEHLEALLKHVT--------------AQGVKENIQEVVGHITEGVCRPLKVRIEQVILAEPGAVLLYKISNLLKFYHHTISGIVGNSAATLLTTIEEMHLLSKKIFFSSLSLHANKLMDK--------IELPPPDLGPSSALSQTLTLLRDVLASHDSSVVPLDARQAD--------FVQVLSCVLDPLLQMCTVSASNLG------TADMATFMVNSLYMMKTTLALFE---------------FTDRRLEMLQFQIEAHLDTLINEQASYVLTRVG-----LSYIYNTIQQHRPDQGSLASMPNLDSVALKAAMAQFDRYLSAPDHLLMPQLNSLLSATVKEQIIKQSTELVCRAYGEVHAAVMNPV-NAYKDPESILHRSPEQVKTLLS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R3I3-1", "uniprot_id": "COG6_MOUSE", "id": "Q8R3I3-1", "name": "Conserved oligomeric Golgi complex subunit 6", "aln": "-----------------------------------------------------------------------------------------------------------MADASGEVAAVPASGAANGFSNGAGATPAQPNNPLSRKLHKILETRLENDKEMLEALKALSAFFVENSLRT-----------------RRNLRGDIERRSLAINEEFVNIFKDVKEELESINEDVQAMSSCCQDMTSRLQAAKEQTQDLIVKTTKLQAENQRLEIRAQVVDAFLAKFQLTSDEMSLLRG-TRGGPVTEDFFKALGRVKQIHNDVKVLLRTNQQTAGLEIMEQMALLQETAYERLYRWAQSECRALTQES----------CDVSAVLSQAMEALQDRPVLYKYTLDEFGTARRSTVVRGFIDALTRGGPGGTPRPIEMHSHDPLRYVGDMLAWLHQATASEKEHLEALLKHVT--------------AQGVKENIQEVVGHITEGVCRPLKVRIEQVILAEPGAVLLYKISNLLKFYHHTISGIVGNSAATLLTTIEEMHLLSKKIFFTSLSLHANKLMDK--------VELPPPDLGPSSALSQTLTLLRDILASHDSSVVPLDARQAD--------FVQVLSCALDPLLQMCTVSASNLG------TADMATFMVNSLYMMKTTLALFE---------------FTDRRLEMLQFQIEAHLDTLINEQASYVLTRVG-----LSYIYNTIQQHRPDQGSLANMPNLDAVALKAAMAQFDRYLSAPDHLLMPQLNSLLSATVKEQIIKQSTELICRAYAEVHAAVMNPD-NAYKDPENILHRSPEQVKTLLS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2V7-1", "uniprot_id": "COG6_HUMAN", "id": "Q9Y2V7-1", "name": "Conserved oligomeric Golgi complex subunit 6", "aln": "-----------------------------------------------------------------------------------------------------------MAEGSGEVVAVSATGAANGLNNGAGGTSATTCNPLSRKLHKILETRLDNDKEMLEALKALSTFFVENSLRT-----------------RRNLRGDIERKSLAINEEFVSIFKEVKEELESISEDVQAMSNCCQDMTSRLQAAKEQTQDLIVKTTKLQSESQKLEIRAQVADAFLSKFQLTSDEMSLLRG-TREGPITEDFFKALGRVKQIHNDVKVLLRTNQQTAGLEIMEQMALLQETAYERLYRWAQSECRTLTQES----------CDVSPVLTQAMEALQDRPVLYKYTLDEFGTARRSTVVRGFIDALTRGGPGGTPRPIEMHSHDPLRYVGDMLAWLHQATASEKEHLEALLKHVT--------------TQGVEENIQEVVGHITEGVCRPLKVRIEQVIVAEPGAVLLYKISNLLKFYHHTISGIVGNSATALLTTIEEMHLLSKKIFFNSLSLHASKLMDK--------VELPPPDLGPSSALNQTLMLLREVLASHDSSVVPLDARQAD--------FVQVLSCVLDPLLQMCTVSASNLG------TADMATFMVNSLYMMKTTLALFE---------------FTDRRLEMLQFQIEAHLDTLINEQASYVLTRVG-----LSYIYNTVQQHKPEQGSLANMPNLDSVTLKAAMVQFDRYLSAPDNLLIPQLNFLLSATVKEQIVKQSTELVCRAYGEVYAAVMNPI-NEYKDPENILHRSPQQVQTLLS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V564-1", "uniprot_id": "COG6_DROME", "id": "Q9V564-1", "name": "Conserved oligomeric Golgi complex subunit 6", "aln": "-----------------------------------------------------------------------------------------------------------MSSTQ---------------------EKPEELDRIQKRVNKILEARLESDKDTLDALSGLSTFFTENTLQN-----------------RRNLRSQIEHRSVGINENFLKAFRQVKLSLDAVCEDLDTMATSVETMKSDLETSKALTKDLIKQTNTMQRERDRLEVHKQIAQAFLARFQLSGAEHQLLYGAAKDAPIVADFFRVLDRVQSIHADCRLLMQCGYQTAAIDIMEEMTLHQEGALERLYRWTQNHCRSLENN------------EIGPLIVEAMSRLQDRPVLFKYVIDEYAIARRAVLVRQFIEALTEGGPGGNPKPIELHAHDPKRYIGDMFAWLHQSIPTEKENLSLLFKKCD--------------KQDISDQLQNALGYIADGVCHPLKVRVETILQAEKDTIVLFTISNLLRFYQQIMRQVVQ--GGSLEECLVELQKSSEQIYLGALAAQVRSVLQRPSGGSGLALEPPQRDLVPPPSVARLLNMLKEILS----VATMVDGRQAD--------ITKIVSCVIDPLLQSVQESAAHLP------TVDMGVYLLNCLHHMQSSLAVYE---------------YMDERVERLQAQSDAQLDTLTSEQASSLVANLN-----LGPIYAILQSNQS---------KIETNLLKIFMSKMDAFLELPDVLLLPQVQLIMSSSHRAAVQKRSFNVIVAIYKQIYERVHDPA-NGFEQPEQLLHRTPEQVAHILTST-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53959-1", "uniprot_id": "COG6_YEAST", "id": "P53959-1", "name": "Conserved oligomeric Golgi complex subunit 6", "aln": "MDFVVDYQTYAMADTATPELPEPEPRLNLTSDAQSQPTGKLDLQFKLPDLQRYSNNNATLPVDNDGAGSKDLHKKMTHYAMSSIDKIQLSNPSKQLGQNSQDEKLSQQESQNFTNYEPKNLDLSKLVSPSSGSNKNTTNLVLSNKLSKILNNYTLINYQATVQLRKSLKVLEENKERLSLDEQKLMNPEYVGTLARRALRTDLESQLLKEHITVLEEFKPIIRRIKRLSSSVEKIQRTSEKLLSNETNEVPTNNVVLQEIDQYRLKAEQLKLKKKILLSIRDRFTLNQVEDDVITN----GTIDNIFFEVVKKVINIKDESSFLLTLPNLNAGNALIMGVNEILEKTNKKIFNYLIDFLYSFESSSNLLNDHGTTEQESLNIFRKSLVFLSSDLELFNELLKRVTTLRSKSILDEFLSQFDMN--STTSKPIILSAHDPIRYIGDVLASVHSIIANEADFVKSLFDFQDEDLKDTPISILQQNKTFLKGIDNKLLNDIIQSLSNSCRIRIEQIVRFEENPIINFEIVRLLKLYRVMFERKGIQDDSSIINNLKSLEDISKNRIIGYYEDYMKQTVMA-------ETKNSSDDLLPPEWLSEYMNKLVELFEIYEKTHAAEDEESEDNKLLSSKNLQTIVEQPIKDVLLKQLQTSFPLAKKNEKEKASLLTIEINCFDLIKSRLQPFEGLFAQDDDSRKITIWVCDKLKEYTKQMLTLQIKFLFENTGLDLYSNLVNMIFPVDSVKDELDYDMYLALRDNSLMELDMVRKNVHDKLNYYLPQALTDVQGNLLFKLTSPMIADEICDECFKKLSLFYNIFRKLLIHLYPNKKDQVFEILNFSTDEFDMLIGIDH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :..:: ***: : : * .: **. : ** ** ::* : : : .:. *: : :. : ..:: : : : * .: :: : : : ::*::: :: :: :* *. * :: . ..: **..: :* .*: : .*: .*. :: : * : ::::.: . :: .. : :: ::: *.. *:: :.. * :: *:. : . . ..:** : :*** **:**::* :*. ..* : :. *:. :. :: :. * :.:... ::*:* :: * ..:: : * .**::*: : :: : .:. *:: : . : : . ** *. : . : * ::: . * .. * : ::. :. :* :: * ...: . :*.: ::: * :* *. * : ::. * .: . : :.: :. : :: . ::: : . : : : *. : ... : : * . : . * .: .:*: :.::. :: ", "identical_positions": 68, "similar_positions": 240, "identity": "7.98%" }, { "cls_id": "homologset.agr.SGD:S000004989", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0S9-1", "uniprot_id": "PRAF1_MOUSE", "id": "Q9Z0S9-1", "name": "Prenylated Rab acceptor protein 1", "aln": "-------MAAQKDQQKDAEGEGLSATTLLPKLIPSGAGREWLERRRATIRPWGTFVDQQRFSRPRNVGELCQRLVRNVEYYQSNYVFVFLGLILYCVVTSPMLLVALAVFFGACYILYLRTLQSKLVLFGREVSPAHQYALAGGVSFPFFWLAGAGSAVFWVLGATLVLIGSHAAFHQMEPADGEE---LQMEPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35394-1", "uniprot_id": "PRAF1_RAT", "id": "O35394-1", "name": "Prenylated Rab acceptor protein 1", "aln": "-------MAAQKDQQKDAEVEGLSATTLLPKLIPSGAGREWLERRRATIRPWGTFVDQQRFSRPRNVGELCQRLVRNVEYYQSNYVFVFLGLILYCVVTSPMLLVALAVFFGACYILYLRTLQSKLVLFGREVSPAHQYALAGGVSFPFFWLAGAGSAVFWVLGATLVLIGSHAAFHQIEPADGEE---LQMEPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UI14-1", "uniprot_id": "PRAF1_HUMAN", "id": "Q9UI14-1", "name": "Prenylated Rab acceptor protein 1", "aln": "-------MAAQKDQQKDAEAEGLSGTTLLPKLIPSGAGREWLERRRATIRPWSTFVDQQRFSRPRNLGELCQRLVRNVEYYQSNYVFVFLGLILYCVVTSPMLLVALAVFFGACYILYLRTLESKLVLFGREVSPAHQYALAGGISFPFFWLAGAGSAVFWVLGATLVVIGSHAAFHQIEAVDGEE---LQMEPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z823-1", "uniprot_id": "A1Z823_DROME", "id": "A1Z823-1", "name": "PRA1 family protein", "aln": "MAHTGGNLSGNMQPPPPSGGRFSVDMQSLPSLSNLPSPLQIFQMVRNSLRPWVVFFNINNFKTAISMQRLNSRVIRNLSYFQANYVFIFFVLMIYCLITAPCILLVILASAFGCHKLRVR--NSNITIVGQQLTPSQQIIALNLATAPVLFLVGAGAVLFWTLGASCFVIAMHAIFYNIDAIVTEENEGFLAQVV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53633-1", "uniprot_id": "PRA1_YEAST", "id": "P53633-1", "name": "Prenylated Rab acceptor 1", "aln": "-------------MNQLGALAQVSRFTQNFSMENIKSEFQSLQSKLATLRTPQEFFNFKKISKPQNFGEVQSRVAYNLKYFSSNYGLIIGCLSIYTLLTNLLLLFVIVLVVAGIVGINKLKGEELVTPFG-SFKTNQLYTGLVCVAVPIGFLASPISTLLWLIGASAVSVFGHASLMEKPIETVFD-----EETV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: : : :: ::*. *.: :.:. . .. .: .*: *:.*:.:** ::: * :* ::* :*..: . : :. :. .* .... : : *. :*... :.::* :**: . : ** : : : : *", "identical_positions": 20, "similar_positions": 68, "identity": "10.26%" }, { "cls_id": "homologset.agr.SGD:S000004990", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P30349-1", "uniprot_id": "LKHA4_RAT", "id": "P30349-1", "name": "Leukotriene A-4 hydrolase", "aln": "------------------------------------------------MPEVADTCS-------------------LASPASVCR-----TQHLHLRCSVDFARRALTGTAALTVQSQED---NLRSLTLDTKDLTIEKVVING----QEVKYTLGESQGYKGSPMEISLPIALSKNQEVVIEISFETSPKSSALQWLTPEQTSGKQHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGEAPDPEDPSRKIYRFNQRVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFS-ETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFHALGGWGELQNTIKT-FGESHPFTKLVVDLKD-VDPDVAYSSIPYEKGFALLFYLEQLLGGPEVFLGFLKAYVEKFSYQSVTTDDWKSFLYAHFKD--KVDLLNQVDWNAWLYAPGLPPVKPNYDVTLTNACIALSQRWVTA------KEEDLNSFSIEDLKDLSSHQLNEFLAQVLQK------------APLPLGHIKRMQEVYN-FNAINNSEIRFRWLRLCIQSKWEEAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKACMHPVTAMLVGKDLKVD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24527-1", "uniprot_id": "LKHA4_MOUSE", "id": "P24527-1", "name": "Leukotriene A-4 hydrolase", "aln": "------------------------------------------------MPEVADTCS-------------------LASPASVCR-----TQHLHLRCSVDFARRTLTGTAALTVQSQEE---NLRSLTLDTKDLTIEKVVING----QEVKYTLGESQGYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKQHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGEAPDPEDPSRKIYRFNQRVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSANEFS-ETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFHALGGWGELQNTIKT-FGESHPFTKLVVDLKD-VDPDVAYSSIPYEKGFALLFYLEQLLGGPEVFLGFLKAYVKKFSYQSVTTDDWKSFLYSHFKD--KVDLLNQVDWNTWLYAPGLPPVKPNYDVTLTNACIALSQRWVTA------KEEDLSSFSIADLKDLSSHQLNEFLAQVLQK------------APLPLGHIKRMQEVYN-FNAINNSEIRFRWLRLCIQSKWEEAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVHTYQEHKASMHPVTAMLVGRDLKVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09960-1", "uniprot_id": "LKHA4_HUMAN", "id": "P09960-1", "name": "Leukotriene A-4 hydrolase", "aln": "------------------------------------------------MPEIVDTCS-------------------LASPASVCR-----TKHLHLRCSVDFTRRTLTGTAALTVQSQED---NLRSLVLDTKDLTIEKVVING----QEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFS-ETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKT-FGETHPFTKLVVDLTD-IDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKD--KVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITA------KEDDLNSFNATDLKDLSSHQLNEFLAQTLQR------------APLPLGHIKRMQEVYN-FNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVTAMLVGKDLKVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJ39-1", "uniprot_id": "Q9VJ39_DROME", "id": "Q9VJ39-1", "name": "Leukotriene A(4) hydrolase", "aln": "MSIAKRVQQWATFARTWHIYDCTWQNPFESAKLVKTHLLGLQKPIYHPMISTRGLCTSHKLLPIYQVQKRNMGRLGVVDPSSYSQPDLITTEHSALNWKIDFAATKIQGSVLHRFKVLTA---NLDKILLDVRDINVTNATLLAGGSELPINFFISDAVDDIGQKLTLELPSGTAKG-SLNVRIDYETSSSASGLQWLNPTQTLGKEHPYMFSQCQAIHARSVIPCQDTPAVKFTYDATVEHPSELTALMSALIDKKEPGK-------TLFKQEVPIPAYLVAIAIGKLVSRPLGENSSVWAEEAIVDACAEEFS-ETATMLKTATELCGPYVWKQYDLLVMPPSFPFGGMENPCLTFVTPTLLAGDKSLADVVAHEIAHSWTGNLVTNKNFEHFWLNEGFTVFVESKIVGRMQGAKELDFKMLSNLTDLQECIRTQLNKTPELTKLVVDLSN-CGPDDAFSSVPYIKGSTFLRYLEDLFGGPTVFEPFLRDYLKKYAYKSIETKDFQSALYDYFIDTDKKDKLSAVDWDLWLKSEGMPPVIPNFDESLANVTKELASLWSSK------SVAELAD-SAEIKTTISIHQLIDFLGKLIESKDI---------VDLNEGKINLLESTYN-LKSSKNAEVRFRLNRLIIRARLIKRLDEILEFANSNFRMKFCRPIYRDLAGWPEAKPAAIRNFVNVKDQMMAVCSHTIEKDLGLK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q10740-1", "uniprot_id": "LKHA4_YEAST", "id": "Q10740-1", "name": "Leucine aminopeptidase 2", "aln": "MFLLPFVIRHSS---SIYLPTLRFRG-LLTVISRNIHISTPHKMLPLSIEQRRPSRSP------------------EYDQSTLSNYKDFAVLHTDLNLSVSFEKSAISGSVTFQLKKLHEGKNKSDELHLDTSYLDVQEVHIDG----SKADFQIEQRKEPLGSRLVINN---ASCNDNFTLNIQFRTTDKCTALQWLNSKQTKG-GKPYVFSQLEAIHARSLFPCFDTPSVKSTFTASIESP--LPVVFSGIRIEDTSKDTN----IYRFEQKVPIPAYLIGIASGDLSSAPIGPRSTVYTEPFRLKDCQWEFENDVEKFIQTAEKIIFEYEWGTYDILVNVDSYPYGGMESPNMTFATPTLIAHDRSNIDVIAHELAHSWSGNLVTNCSWNHFWLNEGWTVYLERRIIGAIHGEPTRHFSALIGWSDLQNSIDS-MKDPERFSTLVQNLNDNTDPDDAFSTVPYEKGFNLLFHLETILGGKAEFDPFIRHYFKKFAKKSLDTFQFLDTLYEFYPE--KKEILDSVDWETWLYKPGMPP-RPHFITALADNVYQLADKWVEMAQHLKTTEDFRSEFNAIDIKDFNSNQLVLFLETLTQNGHSNKKPKDFDWAKFPVASRALLDIYQDNIVKSQNAEVVFKMFKFQIFAKLQEEYKHLADWLGTVGRMKFVRPGYRLLNSVDR--RLALATFDKFKDTYHPICKALVKQDLGL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . :: .. . * *. .:.* : *:. .: : .: **. : : :. : . .: : : *. : :. : . .. :.*.:.*: ..:.****.. ** * :**:*** :***.*:::** ***:** *: * :. * * .::*.: . . * *.****.**:.:. * * * :* .: *::* :. . **. :. .::: * .: * * **:** *:*:****.* :**.****:* *:* :*:***::***:****** .::******* **::* :* * : * .* * . :**: : : : .. ::.** :*.: .** *:*::** ** :* :** ::** * *:: *.:*:: :*: * :: . ** .: : * : *. ***: ** *:** *:: :*:: *:. * . . . . :. :** ** : . : . :: : : :*:*: *: :: * :: . . **** ** :: * . . *: .: : * .: : :** : ", "identical_positions": 163, "similar_positions": 199, "identity": "22.83%" }, { "cls_id": "homologset.agr.SGD:S000004993", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCQ2-1", "uniprot_id": "D3ZCQ2_RAT", "id": "D3ZCQ2-1", "name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "aln": "------MAADTGSWCVYAVLRFFYSLFFPGLIICGVLCVYLVIGLWVIRRHLQRKK---KSASTSKNGKDQMVVAFFHPYCNAGGGGERVLWCALRALQKKYPDAVYVVYTGDIH----VSGQQILEGAFRRFNIKLVHP-VQFVFLRKRYLVEDSRYPHFTLLGQSLGSILLGWEALMQRVPDVYIDSMGYAFTLPLFK-YVGGCRVGSYVHYPTISTDMLSVVKNQNPGFNNAAFISRNALLSKAKLIYYYLFAFVYGLVGSCSDIVMVNSSWTLNHILSLWKVGHCTNIVYPPCDVQTFLDIPLH----EKKVTPGHLLVSIGQFRPEKNHALQIKAFAKLLNEKAAESR--HSLKLVLIGGCRNKDDEFRVNQLRRLSENLG--VQENVEFKINISFDELKNYLSEATIGLHTMWNEHFGIGVVECMAAGTIILAHNSGGPKLDIVIPHEGQ-------------------------ITGFLAESEEG--------------YAETMAHILSLSPEKRLRIRETAR-ASLSRFSDQEFEVAFLCSVGKLLT---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TZM9-1", "uniprot_id": "ALG11_MOUSE", "id": "Q3TZM9-1", "name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "aln": "------MAADTGSWCVYAVLRFFYSLFFPGLMICGVLCVYLVIGLWVIRWHLQRKK---KSVSTSKNGKEQTVVAFFHPYCNAGGGGERVLWCALRALQKKYPEAVYVVYTGDIN----VSGQQILDGAFRRFNIKLAHP-VQFVFLRKRYLVEDSRYPHFTLLGQSLGSILLGWEALMQRVPDVYIDSMGYAFTLPLFK-YVGGCRVGSYVHYPTISTDMLSVVKNQNPGFNNAAFISRNALLSKAKLIYYYLFAFVYGLVGSCSDIVMVNSSWTLNHILSLWKVGHCTNIVYPPCDVQTFLDIPLH----EKKVTPGHLLVSIGQFRPEKNHALQIKAFAKLLNEKAAELG--HSLKLVLIGGCRNKDDEFRVNQLRSLSENLG--VQENVEFKINISFDELKNYLSEATIGLHTMWNEHFGIGVVECMAAGTVILAHNSGGPKLDIVIPHEGQ-------------------------ITGFLAESEEG--------------YADSMAHILSLSAEERLQIRKNAR-ASISRFSDQEFEVAFLCSMEKLLT---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2TAA5-1", "uniprot_id": "ALG11_HUMAN", "id": "Q2TAA5-1", "name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "aln": "------MAAGERSWCLCKLLRFFYSLFFPGLIVCGTLCVCLVIVLWGIRLLLQRKK---KLVSTSKNGKNQMVIAFFHPYCNAGGGGERVLWCALRALQKKYPEAVYVVYTGDVN----VNGQQILEGAFRRFNIRLIHP-VQFVFLRKRYLVEDSLYPHFTLLGQSLGSIFLGWEALMQCVPDVYIDSMGYAFTLPLFK-YIGGCQVGSYVHYPTISTDMLSVVKNQNIGFNNAAFITRNPFLSKVKLIYYYLFAFIYGLVGSCSDVVMVNSSWTLNHILSLWKVGNCTNIVYPPCDVQTFLDIPLH----EKKMTPGHLLVSVGQFRPEKNHPLQIRAFAKLLNKKMVESP--PSLKLVLIGGCRNKDDELRVNQLRRLSEDLG--VQEYVEFKINIPFDELKNYLSEATIGLHTMWNEHFGIGVVECMAAGTIILAHNSGGPKLDIVVPHEGD-------------------------ITGFLAESEED--------------YAETIAHILSMSAEKRLQIRKSAR-ASVSRFSDQEFEVTFLSSVEKLFK---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZW24-1", "uniprot_id": "ALG11_DANRE", "id": "Q7ZW24-1", "name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "aln": "-----MSAHDHFSLCLCDLIRLLWSLMLPCFYLSFLLTTILFLFIMGVRSWLQMKR---KTRRVQ-DGRP--AVAFFHPYCNAGGGGERVLWCALRALQNRYQDVSFVVYTGDQG----VTAEEILDGARRRFNIRLPRP-VKFVFLKHRLLVEAKLYPHFTLLGQSVGSIFLGWEALTEFVPDLYIDSMGFAFTLPVFR-YLGGCQVGSYVHYPTISTDMLSVVRERNPRFNNADYISSNPVLSAIKVIYYCVFALLYGLAGSCSDVIMVNSTWTLGHILALWRTPNRTSVVYPPCDVQAFLDVPIGEDNEEKEQKKCHSLVSVGQFRPEKDHQLQIRAFKKLLDRKEAEPAGREAVKLVLIGGCRNQEDEDRVLMLRGLCQELG--IADRVEFKLNIPFQELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKLDIVVPYDGG-------------------------PTGFLADDEDN--------------YADAMERILSMSPATRLEMRRRAR-LSVSRFSDQEFEGSFLSAMEPLMSTLRA-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VP06-1", "uniprot_id": "Q9VP06_DROME", "id": "Q9VP06-1", "name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "aln": "---------------------MFLFLFLLWLLLSLVLVAVLS-FLFLRQWLLGRKN---KLHTSSENGIN---VGIFHPYCNAGGGGERVLWCAVRALQEKYQNARMVIYTGDID----ASPNSILQKAKNVFNIAVDSDNVKFVFLKQRHWIEAKNYPHFTLLGQSIGSMVVGLEALCRFPPDIYIDTMGYAFTYPLFR-YLAQSKVGCYVHYPVISTDMLKRVQQRQMSHNNKKYVARNPFLTWTKLAYYRLFSRMYKWVGCCAETIMVNSSWTENHILQLWDVPFKTHRVYPPCEVSHLKSLQHT----EKGDE--FIILSVGQFRPEKDHPLQLQAIYELRTLLAQDEALWNQIKLVIVGSCRNEDDYERLKNMQDLTKHLS--LENNVQFSVNVPYEDLLKLYQTAHIGIHTMWNEHFGIGIVESMAAGLIMVAHKSGGPLLDIVETSAGS-------------------------QNGFLATDAVE--------------YAENILNIIVNNSE-MNGIRNAAR-ASVERFSEQEFEKNFLRAVSTLFTNN-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53954-1", "uniprot_id": "ALG11_YEAST", "id": "P53954-1", "name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "aln": "MGSAWTNYNFEEVKSHFGFKKYVVSSLVLVYGLIKVLTWIFRQWVYSSLNPFSKKSSLLNRAVASCGEKNVKVFGFFHPYCNAGGGGEKVLWKAVDITLRKDAKNVIVIYSGDFVNGENVTPENILNNVKAKFDYDLDSDRIFFISLKLRYLVDSSTWKHFTLIGQAIGSMILAFESIIQCPPDIWIDTMGYPFSYPIIARFLRRIPIVTYTHYPIMSKDMLNKLFK----------MPKKGIKVYGKILYWKVFMLIYQSIGSKIDIVITNSTWTNNHIKQIWQS-NTCKIIYPPCSTEKLVDWKQKFG--TAKGERLNQAIVLAQFRPEKRHKLIIESFATFLKNLPDSVS---PIKLIMAGSTRSKQDENYVKSLQDWSENVLKIPKHLISFEKNLPFDKIEILLNKSTFGVNAMWNEHFGIAVVEYMASGLIPIVHASAGPLLDIVTPWDANGNIGKAPPQWELQKKYFAKLEDDGETTGFFFKEPSDPDYNTTKDPLRYPNLSDLFLQITKLDYDCLRVMGARNQQYSLYKFSDLKFDKDWENFVLNPICKLLEEEERG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : * : : : * : . . ..:************:*** *: .: . *:*:** .. :.**: . *: : : *: *: * :: . : ****:**::**:.:. *:: . **::**:**:.*: *:: :: : *.*** :*.***. : : :. : . *: *: :* :* *. : ::.**:** .** :* :****... : . : :.****** * * :.:: : . :**:: *. *.::* : :: :.: . :.*. *:.::.: : :*:::********.:** **:* : :.* *.** **** . . .**: . :: : .* . : : *: :**: :*: : : : ", "identical_positions": 113, "similar_positions": 148, "identity": "20.04%" }, { "cls_id": "homologset.agr.SGD:S000004994", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZA8-1", "uniprot_id": "D3ZZA8_RAT", "id": "D3ZZA8-1", "name": "", "aln": "MAQPRIPAARGAAAGLQAQNGAASA------------SGSPYTNGPVQHTLMSSQVSLSQGYDSQLPG-----------------------SYPHPMPAKTLNPFSAQSNYGGSQGSG----------------QALNSPLVTSSPVPPSLHSGPVPRMALPTSQNPAATPMP---------------SGSFPPGTNPAPPLNWQYNHPSTGPQTNHFP-HVAQPTIPGNTDFTADH-------------------------------PYVSSGDPALQTS---FKKPG-SALPLQN--------------------PPLPPTFQP----GAPP----GPPPAGGPP--PSRGPVPQK---------------------------------------------------------TPPRAAFPPSLNSAVNQEG---------ITSNANTG-SAAHSTYDEIEGG---------------------GFLATPQLVNQ-------NPKTSRSVGYAYP--SLPPGYQNTAPP-VAGMPPSSLN--YPSGPQAFTQAPLGANHLTASMSGLSLH----PEGLRVVNLLQERNMLPSTPLQPPVPNLLEDVQK-LNCNPELFRCTLTSVPQTQALLNKAKLPLGLLLHPFKDLV----QLPVVTSSTIVRCRSCRTYINPFVNFLDQ-RRWKCNLCYRVNDVPEEFMYNPLTRVYGEPHKRPEVQNATIEFMAPSEYMLRPPQPPVYLFVFDVSHNAIETGYLNSVCQSLLDNLDLLP-GNTRTKIGFITFDSTIHFYSLQEG-----------------------------LSQPQMLIVSDIDDVFIPMP-ENLLVNLNESKELVQDLLKTLPQMFTKTLETQSALGPALQAAFKLISPTGGRMSVFQTQLPTLGVGALKPREEPNQRSSAKEI-HLTPSTD-FYKKLALDCSGQQAAVDLFLLSGQYSDLASLGCISRYSAGSVYYYPSYHHQHNPVQVQKFQKELHRYLTRKIGFEAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLPNVNPDAGYAVQMSVEESLTDTQLVSFQSALLYTSSKGERRIRVHTLCLPVVSTLNEVFLGADVQAISGLLANMAVDRSVTASLSDARDALVNAVIDSLSAYRSS--VLSSQ-QPGLMVPFSLRLFPLFVLALLKQKSFQTGTNVRLDERIFAMCQVKNQPLVHLMLTTHPSLYRVDNLSDEG-ALNIN---------DRTIPQPPILQLSVEKLSRDGAFLMDAGSVLMLWVGRNCAQNFLSQVLGVQNYASIPQTMTDLPELDT-PESARMTAFISWLREQR--PFFPILYVIR--------------EESLMKAAFLQNLVEDRTESALSYYEFLLHIQQQVNK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U2P1-1", "uniprot_id": "SC24A_MOUSE", "id": "Q3U2P1-1", "name": "Protein transport protein Sec24A", "aln": "MAQPRIPAARGAAASLQAQNGAASA------------SGSPYTNGPVHNTLMSPQVSSSQGYDSQPPG-----------------------SYPRPMPAKTLNPFSAQSNYGGSQGSG----------------QTLNSPLVTSGPVLPSLHSGPVPRMPLPTSQNPAATPMP---------------SGSFLPGANPPPPLNWQYNYPSTGPQTNHFP-HVAPPTLPGNPNLTADH-------------------------------QYVSSGDPALQTS---FKKPG-SALPLQN--------------------PPLPPTFQP----GAPP----GPPPAGGPP--PSRGPAPQK---------------------------------------------------------TPPRAAPPPSFNSAVNQEG---------ITSNANNGSTAAHNTYDEIEGG---------------------GFLATPQLVNQ-------NPKTSRSVGSAYP--SLPPGYQNSAPP-VAGMPPPSLS--YPSGPQAFTQTPLGANHLTASMSGLSLH----PEGLRVVNLLQERNMLPSTPLQPPVPNLLEDIQK-LNCNPELFRCTLTSVPQTQALLNKAKLPLGLLLHPFKDLV----QLPVVTSSTIVRCRSCRTYINPFVNFLDQ-RRWKCNLCYRVNDVPEEFMYNPLTRVYGEPHKRPEVQNATIEFMAPSEYMLRPPQPPVYLFVFDVSHNAIETGYLNSVCQSLLDNLDLLP-GNTRTKIGFITFDSTIHFYSLQEG-----------------------------LSQPQMLIVSDIDDVFIPMP-ENLLVNLNESKELVQDLLKTLPQMFTKTLETQSALGPALQAAFKLISPTGGRMSVFQTQLPTLGVGALKPREEPNQRSSAKEI-HLTPSTD-FYKKLALDCSGQQAAVDLFLLSGQYSDLASLGCISRYSAGSVYYYPSYHHQHNPVQVQKLQKELHRYLTRKIGFEAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLPNVNPDAGYAVQMSVEESLTDTQLVSFQSALLYTSSKGERRIRVHTLCLPVVSTLNEVFLGADVQAISGLLANMAVDRSVTASLSDARDALVNAVIDSLSAYRSS--VLSGQ-QPGLMVPFSLRLFPLFVLALLKQKSFQTGTSIRLDERIFAMCQVKSQPLVHLMLTTHPSLYRVDNLSDEG-ALNIN---------DRTIPQPPILQLSVEKLSRDGAFLMDAGSLLMLWVGRNCSQNFLSQVLGVQNYASIPQTMTDLPELDT-PESARIAAFISWLREQR--PFFPVLYVIR--------------EESLMKAAFLQSLVEDRTESALSYYEFLLHIQQQVNK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95486-1", "uniprot_id": "SC24A_HUMAN", "id": "O95486-1", "name": "Protein transport protein Sec24A", "aln": "MSQPGIPASGGAPASLQAQNGAALA------------SGSPYTNGPVQNALLSSQESVSQGYNFQLPG-----------------------SYPHPIPAKTLNPVSGQSNYGGSQGSG----------------QTLNRPPVASNPVTPSLHSGPAPRMPLPASQNPATTPMP---------------SSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNH-------------------------------QYVSSGYPSLQNS---FIKSGPSVPPLVN--------------------PPLPTTFQP----GAPH----GPPPAGGPP--PVRALTPLT---------------------------------------------------------SSYRDVPQPLFNSAVNQEG---------ITSNTNNGSMVVHSSYDEIEGG---------------------GLLATPQLTNK-------NPKMSRSVGYSYP--SLPPGYQNTTPPGATGVPPSSLN--YPSGPQAFTQTPLGANHLTTSMSGLSLQ----PEGLRVVNLLQERNMLPSTPLKPPVPNLHEDIQK-LNCNPELFRCTLTSIPQTQALLNKAKLPLGLLLHPFKDLV----QLPVVTSSTIVRCRSCRTYINPFVSFLDQ-RRWKCNLCYRVNDVPEEFLYNPLTRVYGEPHRRPEVQNATIEFMAPSEYMLRPPQPPVYLFVFDVSHNAVETGYLNSVCQSLLDNLDLLP-GNTRTKIGFITFDSTIHFYGLQES-----------------------------LSQPQMLIVSDIEDVFIPMP-ENLLVNLNESKELVQDLLKTLPQMFTKTLETQSALGPALQAAFKLMSPTGGRMSVFQTQLPTLGVGALKPREEPNHRSSAKDI-HMTPSTD-FYKKLALDCSGQQVAVDLFLLSGQYSDLASLGCISRYSAGSVYYYPSYHHQHNPVQVQKLQKELQRYLTRKIGFEAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLPNVNPDAGYAVQMSVEESLTDTQLVSFQSALLYTSSKGERRIRVHTLCLPVVSTLNDVFLGADVQAISGLLANMAVDRSMTASLSDARDALVNAVIDSLSAYRSS--VLSNQ-QPGLMVPFSLRLFPLFVLALLKQKSFQTGTNARLDERIFAMCQVKNQPLVYLMLTTHPSLYRVDNLSDEG-ALNIS---------DRTIPQPPILQLSVEKLSRDGAFLMDAGSVLMLWVGKNCTQNFLSQVLGVQNYASIPQPMTDLPELDT-PESARIIAFISWLREQR--PFFPILYVIR--------------DESPMKANFLQNMIEDRTESALSYYEFLLHIQQQVNK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PSG8-1", "uniprot_id": "A0A8M1PSG8_DANRE", "id": "A0A8M1PSG8-1", "name": "", "aln": "MSSGQFAPQNGAGDSFA--NGPSQN------------AVYPLNPGFMAPPLQPGYISSVPAKGLPAGP-----------------------QSCYNTHRHQPSPVGTHSPLPASPNHR----------------PVLPGPPQAS-PTPPPHANSHYQHTQQPSSWSSTAAVFQ---------------STAAPPALNVMAPH--QTFGPPPAAMRGTPPLTVPPPTVAP-PPFAAAP-------------------------------PPSTIAPPPFAAA---PPPSTIAPPPFAA--------------------APPPSTIAPPPFVAAPPPSTIAPPPFAGAP--PTSTVLPP-----------------------------------------------------------PRAGVPPPSASAAVPPPP---------TGAHSDAGPYHLGQMSRPVGSG---------------------YPSLQPGYSTA-------QGYTPPVGQIQHPPGQIQPSSMGQIHP-TAQIPPPSAGQFHPAGQIPPSAQQAGLSPSLAALSLQSHT----PEALRVLNLLQERNLLPHTAVTPPLPCLPQDLQR-MNCSPEVFRCTLTSIPQTQALLNKAKLPLGLLLHPFKDLS----QLPVVTSSNIVRCRSCRTYINPFVTFVGP-TRWKCNLCHRINEVPEEFMYNPVSKSYGAPHKRPEVQNATIEFIAPSEYMLRPPQPAVYLFVLDVSHNAVETGYLDAVCRSLLDNLSSLP-GDARTKIGFITFDSTIHFYSLQEG-----------------------------LSRPQMLIVSDIDDVFLPTQ-DGLLVNLNECKELVQDLLSSLPQMWRQTMETHSALGPALQAAFKLLSATGGRISLFQTQLPTLGIGALKPREQPSTKTQAKDIQHLSPATD-FYKKLALDCSGQHVAVDLFLLSAQYCDLSSLGCISRYSAGSVFYYPSYHTLHNPAQAERFQKDLKRYLTRKIGFEAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLANVNPDAGFAVQMNIEENLLDLQTVSFQAALLYTSSKGERRIRVHTLCLPVVNSLSDIFAGADVQAITALLASMAVDRSVTASVSDARDALVNAAVDMLSSYRSS--VLTVP-QPGLLAPACLRLFPLYILALLKHKAFGTSSATRLDERMFCMCQLKQQPLAYAMLSIHPSLYRVDDLTDEG-ALNVN---------DCTIPQPRVQQLSVEKLSRDAAFLMDCGSVLYLWIGRNCNPAFLTQVLGVDGYANIPLNMTQLPELDT-AESCRMRAFVDWLRERR--PFHPLLHVIR--------------DESPLKAEFLQLMIEDRSESALSYYEFLLHLQQQSSK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O95487-1", "uniprot_id": "SC24B_HUMAN", "id": "O95487-1", "name": "Protein transport protein Sec24B", "aln": "MSAPAGSSHPAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLHHQNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPS--------QQHHQQQSLSGYSTLTWSSPGLPSTQDN---LIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQ------------------------------------------QKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYP--TLQPGYQNATAPLISGVQPSNPV---YSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVWAPVPNLNADLKK-LNCSPDSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLT----QLPVITSNTIVRCRSCRTYINPFVSFIDQ-RRWKCNLCYRVNDVPEEFMYNPLTRSYGEPHKRPEVQNSTVEFIASSDYMLRPPQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLP-GDSRTRIGFMTFDSTIHFYNLQEG-----------------------------LSQPQMLIVSDIDDVFLPTP-DSLLVNLYESKELIKDLLNALPNMFTNTRETHSALGPALQAAFKLMSPTGGRVSVFQTQLPSLGAGLLQSREDPNQRSSTKVVQHLGPATD-FYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIYYYPSFHYTHNPSQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLLSLANINPDAGFAVQLSIEESLTDTSLVCFQTALLYTSSKGERRIRVHTLCLPVVSSLADVYAGVDVQAAICLLANMAVDRSVSSSLSDARDALVNAVVDSLSAYGST--VSNLQ-HSALMAPSSLKLFPLYVLALLKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLYRIDRLTDEG-AVHVN---------DRIVPQPPLQKLSAEKLTREGAFLMDCGSVFYIWVGKGCDNNFIEDVLGYTNFASIPQKMTHLPELDT-LSSERARSFITWLRDSR--PLSPILHIVK--------------DESPAKAEFFQHLIEDRTEAAFSYYEFLLHVQQQICK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LR69-1", "uniprot_id": "A0ABK0LR69_RAT", "id": "A0ABK0LR69-1", "name": "", "aln": "MSAPAGSPHPAAGARMPPKLGGAVS-----------GLAPPQQNGPAQSQMQVPSGYGLPHQNYMAPSGHYSQGPGKMTSLPLDNQCENYYSRPYTAPTQNVGTPSSANQPGAQLMYGRGPSAPHMGASMPGPFQGAPASASHSYPSASQPYSSLGNRYSSPATYSATASVASQGYPSTCSHYPISTVSNVVYPNVSYPSLPASEPYGQMFTSQSAPPPARPLKESYSGPSTAVAYPSRPPPPPSQHQQQQQQQQQQQQQSHSGYSSLPWSGPGLPPAQDS---LIRNQMGSLAIPNSHPAIN----------ENVQPPKPSSVVATVLPGPS---STRMPPAPSHPVGPVPSAPPPPEQMQTKVRFPVPSHAGCGKWRPVNRDPGLWGTYIGRMRERPPEKFANKGMQYGDYVNNQASSTPTPLSSASDDEEEEDEDEEAGVDSSSTTSSASPLPNSYDALEGGSYPDMHSSSASSPVPDRAPEPNSTLVPTPTAA------QPAKVAKPFGYGYP--TLQPAYQNAAAPPTT-AHPSGPA---YSG---YPQQYPGVHQLSSGLGGLSLQSSPQPESLRPVNLTQEKNILPATPIWAPVPNLSAELSK-LNCSPDSFRCTLTSIPQTQALLNKAKLPLGLLLHPFRDLT----QLPVITSNTIVRCRSCRTYINPFVSFIDQ-RRWKCNLCYRVNDVPEEFLYNPLTRSYGEPHKRPEVQNSTVEFIASSDYMLRPPQPAVYLFVLDVSHNAVEAGYLTVLCQSLLENLDKLP-GDSRTRIGFMTFDSTIHFYNLQEG-----------------------------LSQPQMLIVSDIDDVFLPTP-DSLLVNLYESKELIKDLLNALPNMFINTRETHSALGPALQAAFKLMSPTGGRVSVFQTQLPSLGAGLLQSREDPNQRSSTKVVHHLGPATD-FYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIFYYPSFHSTHNPSQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLLSLANINPDAGFAVQLSIEESLADTSLVCFQTALLYTSSKGERRIRVHTLCLPVVSSLADVYAGVDVQAAICLLANMAVDRSVSSSLSDARDALVNAVVDPLSAYSSA--VSSVP-RSTLTAPSSLKLLPLYVLALLKQKAFRTGTSTRLDDRVYAMCQMKSQPLVHLMKMIHPNLYRIDRLTDEG-AIHVN---------DRVVPQPPLQKLSAEKLTREGAFLMDCGSVFYIWIGKGCDSNFIENVLGYPDFGSIPQKMTHLPELDT-LPSERTRSFVTWLRDSR--PLSPVLHVVK--------------DESPARTDFFQHLVEDRTEAALSYYEFLIHVQQQVCK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A1Z813-1", "uniprot_id": "A1Z813_DROME", "id": "A1Z813-1", "name": "", "aln": "MSTYNPNFVPPAHAPMPLNGNNFVNG---------VQGSVQQQPGPPPGQQYIPQKQPQQFQQPPPAAAFPGAG----------------APGNVPPPQQFNSGITNQFLPPTSGAATPLQQLPPSTLPPHLRPPAANGPPLTNGSNGASSANSSRTASPRPVGAAPQYAQGP------------IAAALNNPPLASGLRPSPQPTHQSLANLTSNLENLNLNTTRANGGTSILPQPQTQQQYAP-------------TVTQKDGRGVASAQTGPPQFNDANSLLAASGVAAALVPNAMATPFS-----------GQKPPNLAPNPAKMFGSASMAGRPTPAGQRIPYGVPPPTNPEQQSQQ----------------------------------------------------NNNLQNAPPPPRVGAVWPPS---------LPNVAAPGAQPMMPPAQQTPQTYP------------------YSQVYQPGPQQQ--------PPPPQSAVQPPPPGMFGTQPTGAPLQYQAQAPPQAYG----QHPQQAPQTAPGGPYGTTAPLNVAQQGFSRLWGQDTIDLMQNRHILTPATLPPPKVVLHNQFHESINCSPSIMRCTLTKIPESNSLLQKSRLPLGIVIHPFRDVN----SLPVIQCINIVRCRLCRTYINPFVYFVDS-KMWKCNLCYRVNELPDDFQFDPATKTYGDVTRRPEVRSSTIEFIAPSEYMLRPPQPAMYLFLFDVSIIAQQSGYLEAACAVLNRHLDEMP-GDARTQVGFICFDSFVHFYSMAEG-----------------------------LNQPHEMTLLDIEDPFLPRP-DSLLVNLKECKELVRDLLKQLPKRFAHTHDPGSALGAALQVAFKLMQASGGRITVFQSCLPNKGPGALEPREDPNNRS-AKDVAHLNPATD-FYKRFALECSGYQIACDLFLMNQQYSDMATISGISKHSGGCVHHFPLYQKTK-PHMVESFRSCFKRYLTRKIGFEAVMRIRCTRGLQVHTFHGNFFVRSTDLLSLPNVNPDAGYGMQISYEESLTDAKTICFQAALLYTNSEGERRIRVHTVCLPVTASLPEVMHSADTEAIIGLLSKMAVDRSVASNLSDARDAFINATIDVYNAFKIAQNLPSGQ-SGQLIAPRSLALLPLYILALLKHPAFRVGTSTRLDDRVYAMDCMKTLPLDQLMKYVYPELYKIDALIYHARNSNISSNQDDDEDEDEPLPELPRLQLSAEHLDSRSIFLMDCGTLIMIYVGLNVPPDVLEAVLGISSTAELGDYVYGLPNVVS-NENDVLKRFILRLNYDK--PYSALVQIIR--------------DTSTAKGQFTERLTDDRSESSLSYYEFLQHIRAQVK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53953-1", "uniprot_id": "SFB2_YEAST", "id": "P53953-1", "name": "SED5-binding protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MSHHKKRVYPQAQVPYIASMP--------------IVAEQQQSQQQIDQTAYAMGNLQLNNRANSFTQLAQNQQFPGSGKVVNQLYP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDLFTELPPPIRDLSLPPLP----------------------------------------------------------------------------------------------------------------------------------------------------ITISQDNIVTPSEYS---------------NVPYQYVRSTLKAVPKTNSLLKKTKLPFAIVIRPYLHLQDSDNQVPLNTDGVIVRCRRCRSYMNPFVVFINQGRKWQCNICRFKNDVPFGFDQN-LQGAPINRYERNEIKNSVVDYLAPVEYSVREPPPSVYVFLLDVSQNAVKNGLLATSARTILENIEFLPNHDGRTRIAIICVDHSLHYFYVPLDDDYEVSDEDDEESDGEEEDEDEEEEDVDNSETIQMFDIGDLDEPFLPMPSDELVVPLKYCKNNLETLLKKIPEIFQDTHSSKFALGPALKAASNLIKSTGGKVEVISSTLPNTGIGKLKKRSEQGILNTPKESSQLLSCKDSFYKTFTIECNKLQITVDMFLASEDYMDVATLSHLGRFSGGQTHFYPGFNATS-LNDVTKFTRELSRHLSMDISMEAVMRVRCSTGLRATSFFGHFFNRSSDLCAFSTMPRDQSYLFGISIEDSLMA-EYCYLQVSTLLTLNTGERRIRVMTLALPTSESAREVFASADQLAITDFMTQNAVTKALNSSMYSARDFITKSLEDILNAYKKEISMSNINSVTSLNLCANLRMLPLLMNGLSKHIALRPGVVP-SDYRASALNRLETEPLHYLIKSIYPTVYSLHDMPDEVGLPDFEG--------KTVLPEP--INATISLFERYGLYLIDNSAELFLWVGGDAVPELLIDVFNTDTISQIPVGKSELPLLNDSPFNERLRRIIGRIRENNDTITFQSLYIIRGPSINEPANLNSEKDMASLRLWVLSTLVEDKVLNCASYREYLQSMKTSINR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . : . * : : : *:. : . * . .*.**. :*::::**:*::**:.::::*: .: .:*: ***** **:*:**** *:. *:**:* *::* * : .* *::.:.::::*. :* :* * *.:*:*::*** * : * * . : ::. :* : **::.:: .* :*:: : . . : : : *::: *:* : *:* * .*: :. **. :*: : .* .. ***.**:.* :*:..:**:: ::.: **. * * *: *.: . . .* :: ...* *** ::::*. : : *:** . :* *::::. :.:.*.* ..:* :: . : : *:*: .*.:*****:**: ** :*.*:** **:** ::..: * .: . :. *:.* . :* : * * . ******* *:.**. : :: ..* * :::. ** ::: :.: .*** : :: * .:: : . * * ::** : .* *: :: . * * .: :: ** : :* :* :. : . ... . :*: : : . : . :*:* .: : :::* . .: *:. ..: ** : . :: :. . : ::: : : : . . : :*: . ** *:* :: . ", "identical_positions": 163, "similar_positions": 280, "identity": "11.69%" }, { "cls_id": "homologset.agr.SGD:S000004996", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L5P4-1", "uniprot_id": "A0ABK0L5P4_RAT", "id": "A0ABK0L5P4-1", "name": "Conserved oligomeric Golgi complex subunit 5", "aln": "-------------------------------MEGGDSTVSVAGRGASGSAAVAATVQELLQDDCYSEFLSEDFDVKTYTSQSIHQAVIAEQLAKLAQGISQLDKELHLQVVARHEDLLAQATGIESLEGVLQMMQTRIGALQGAVDRMKSKIVEPYNKIVARTAQLARLQVACDLLRRIIRILYLSKRLQGQLQGGSREITKAAQSLNELDYLSQGIDLSGIEVIENDLLFIARARLEVENQAKRLLEQGVETQNPTQVGTALQVFHNLGTLKDTVTNVVDGYCAALEDSINNALDVKVLTQPSQSAARGGPGRATMPTPGNTAAFRASLWTNMEKLMDHICAACGQVQHLQKVLTKKRDPVSHICFIEEIVKDGQPEILYMFWNAVTLALSSHFHAATDSSMFLKQAFEGEYPKLLRLYNDLWKRLQQYSQNSQGAFGTRGTADLYADLPDVDDDAQDMSTLKRPDYDPEKALKDSLQPYEAAYLSKSLSRLFDPINLVFPPGGRNPPSSDELDGIIKTIASELNVAAVDANLTLAVSKNVAKTIQLYAVKSEQLLSTQGDASQVIGPLTEGQKRNVGVVNSLFKLHQSVTKVVASQ----SSFSAAAEQTIMSALKTIHDLMGNAIQPLLTSVADAIEAIIITVHQEDFSGSLTSSGKPDVPCSLYMKELQGFIARVMNDYFKHFECLDFVFDNTEAIAQRAIELFIRNASLIRPLGEGGKLRLAADFAQMELAVGPLCRRVSDLGKSYRMLRSFRPLLFQTSEHVADSPAVG-DIIPFSIIIQFLFTRAPAELKSPFQRAEWSHARFSQWLDDHPSEKDRLLLLRGALEAYVQSVRGREGKEFAPVYPILVQLLQKAMSALQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C0L8-1", "uniprot_id": "COG5_MOUSE", "id": "Q8C0L8-1", "name": "Conserved oligomeric Golgi complex subunit 5", "aln": "-------------------------------MEGGDSTISVAGRGASGSAVVAATVQAILQDDCYSEFLNEDFDVKTYTSQSIHQAVIAEQLAKLAQGISQLDKELHLQVVARHEDLLAQATGIESLEGVLQMMQTRIGALQGAVDRMKSKIVEPYNKIVARTAQLARLQVACDLLRRIIRILYLSKRLQGQLQGGSREITKAAQSLNELDYLSQGIDLSGIEVIENDLLFIARARLEVENQAKRLLEQGVETQNPTQVGTALQVFHNLGTLKETVTSVVDGYCAALEDSINNALDVKVLTQPSQSAVRGGPGRAAMPTPGSTAGFRASLWTNMEKLMDHICAACGQVQHLQKVLTKKRDPVSHICFIEEIIKDGQPEILYMFWNAVTLALSSHFHSATNSSMFLKQAFEGEYPKLLRLYNDLWKRLQQSSQNTQGTFSPSGTPDLCVDLPHMEDDTQDMFRLKRPDYDPEKALKDSLQPYEAAYLSKSLSRLFDPINLVFPPGGRNPPSSDELDGITKTITSELNVAAVDANLTLAVSKNVAKTIQLYAVKSEQLLSTQGDASQVIGPLTEGQKRNVGVVNSLFKLHQSVTKVVASQ----SSFSATAEQTIMSALKTIHDLMGNAIQPLLTSVADAIEAIIITMHQEDFSGASSSSGKPDVPCSLYMKELQGFIARVMNDYFKHFECLDFVFDNTEAIAQRAIELFIRNASLIRPLGEGGKLRLAADFAQMELAVGPLCRRVSDLGKSYRMLRSFRPLLFQTSEHVADSPAVG-DIIPFSIIIQFLFTRAPAELKSPFQRAEWSHARFSQWLDDHPSEKDRLLLLRGALEAYVQSVRSRDGKEFAPVYPIMVQLLQKAMSALQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UP83-2", "uniprot_id": "COG5_HUMAN", "id": "Q9UP83-2", "name": "Conserved oligomeric Golgi complex subunit 5", "aln": "MGWVGGRRRDSASPPGRSRSAADDINPAPANMEGGGGSVAVAGLGARGSGAAAATVRELLQDGCYSDFLNEDFDVKTYTSQSIHQAVIAEQLAKLAQGISQLDRELHLQVVARHEDLLAQATGIESLEGVLQMMQTRIGALQGAVDRIKAKIVEPYNKIVARTAQLARLQVACDLLRRIIRILNLSKRLQGQLQGGSREITKAAQSLNELDYLSQGIDLSGIEVIENDLLFIARARLEVENQAKRLLEQGLETQNPTQVGTALQVFYNLGTLKDTITSVVDGYCATLEENINSALDIKVLTQPSQSAVRGGPGRSTMPTPGNTAALRASFWTNMEKLMDHIYAVCGQVQHLQKVLAKKRDPVSHICFIEEIVKDGQPEIFYTFWNSVTQALSSQFHMATNSSMFLKQAFEGEYPKLLRLYNDLWKRLQQYSQHIQGNFNASGTTDLYVDLQHMEDDAQDIFIPKKPDYDPEKALKDSLQPYEAAYLSKSLSRLFDPINLVFPPGGRNPPSSDELDGIIKTIASELNVAAVDTNLTLAVSKNVAKTIQLYSVKSEQLLSTQGDASQVIGPLTEGQRRNVAVVNSLYKLHQSVTKVVSSQ----SSFPLAAEQTIISALKAIHALMENAVQPLLTSVGDAIEAIIITMHQEDFSGSLSSSGKPDVPCSLYMKELQGFIARVMSDYFKHFECLDFVFDNTEAIAQRAVELFIRHASLIRPLGEGGKMRLAADFAQMELAVGPFCRRVSDLGKSYRMLRSFRPLLFQASEHVASSPALG-DVIPFSIIIQFLFTRAPAELKSPFQRAEWSHTRFSQWLDDHPSEKDRLLLIRGALEAYVQSVRSREGKEFAPVYPIMVQLLQKAMSALQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJD3-1", "uniprot_id": "COG5_DROME", "id": "Q9VJD3-1", "name": "Conserved oligomeric Golgi complex subunit 5", "aln": "-------------------------------MVTGDPVATKTPNAADSD--------------------------DNDFTASMSHLTIGQQIQELSKQLQNTKEELHQQVRDKHGALLQQATHAGRFDAALNALAEDVQRVRETGHRLKNQVDTQYQQVENQTQVLGRLHDVSHLLRSAGTLLSLTAKLK-----ATKDVLRLAEIHFELGQLIEDKELKDIDFIQQERAYVISSAQKIRNLTQMQLVTGLQERNENQVVNALKIFMNFNTLEKSLDNLLATFIADMEQSLKECFAGNDISVLNKSPTHNVSKPAPSRGPGKTPQLTTTQNFRAKFWKSLHWLLYDELFETCTQIKLLKTALEQINQFGYTSESSDQCIPQRFWQQVQQLLRKSFDECP---QHVTQTLQEGLSKLLTSARGLEQRLHGEFQFDN----------------------------------------ELFAPLEVGYVSKCAANFKACLAGVDLPG------NETVDNFIRVASTELSAALIDSRLTNAIANVFAACGKELCTKLEAQIKLGADSKQVVDLPNLQQQQNTQLANVLFYYKDSVRRMLSDLHVHFEKTPGTAREIISRSLEQADLLIGTILQQIMESIITTISIIVLSMHRE---PGLNSERMSTTGPSMYMKELQEFVNRSWSHHIALFDDKQMTKKCGHELAKRCIELFLHNVCILRPLSSCGRQRLKQDCQHMEQALKPLCPNLAELGKPSRLLRAMSLLIVQTAEELVKQTIGEDSLVPSYIVLLLLFGHAGADLQSPHTTANWSNERLIEWLDGHTAEREKLELISGALQRYRDNARRKNIQQYDEVYPMMVDYFEQALKALP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53951-1", "uniprot_id": "COG5_YEAST", "id": "P53951-1", "name": "Conserved oligomeric Golgi complex subunit 5", "aln": "----------------------------------------------------------------------------MTIAPMANDLEDFESLLEPDFDAKQFGNDLLKATNNNDTTILDLNTPLKKLNYDLHEIDSRIDQLMNSNP--LEIIELIYKNEHVNSTIVGELKPSLGYMN------------------------------------MSYDRLKNQVLDPYERARKVQLALSKVYQTSFLLRGALLYIHLS---NKLNALSKTAQLSTSTAINLASLHYQLEITLEENKNLKSLRKIKQLDQDIVSP-------------------NKRELITFLSLQMCKECLNSIKIKSNKEIISQLAYSLYLLSS------QEFESAINKIVLSN------------------------------------------------------------------------------------VTMSSQILSKILNSIRMFP-----------------DAFNEVVEKGYNIYILETLLQNIKTDNVTNSSRSIAANKSRLGNLLSEYTSMKSKAGSGTPRDLFWS------------------------------KVSSAFKKDFDISVNRGGPVGKSLLKNKDFIINTMKQSMKKSSDNSDYQS------YLDVMLNSVSISLNK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :.: : .: .:* . .. :* * :: *: : : : : : *:: .: :..*: :. . *.. . : . :. * .: : . . *: : : *. : : :* .::. : : .: . . . : : : :.:: .. * . : : . . . :** : * : .. . . ::: * :. .: : ..: . . .: ..: . :: : ::: : . : *: . *: ::::. . .*. . *:. : : .. ", "identical_positions": 20, "similar_positions": 131, "identity": "2.31%" }, { "cls_id": "homologset.agr.SGD:S000004997", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10888-1", "uniprot_id": "COX41_RAT", "id": "P10888-1", "name": "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial", "aln": "---------MLATRALSLIGKRAISTSVC-----LRAHGSVVKSEDYALPSYVD---RRDYPLPDVAHVKLLSASQKALKEKEKADWSSLSRDEKVQLYRIQFNES---FAEMNKGTNEWKT--VVGLAMFFIGFTALVLIWEKSYVYGPIPHTFDRDWVAMQTKRMLDMKVNPIQGFSAKWDYNKNEWKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19783-1", "uniprot_id": "COX41_MOUSE", "id": "P19783-1", "name": "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial", "aln": "---------MLASRALSLIGKRAISTSVC-----LRAHGSVVKSEDYAFPTYAD---RRDYPLPDVAHVTMLSASQKALKEKEKADWSSLSRDEKVQLYRIQFNES---FAEMNRGTNEWKT--VVGMAMFFIGFTALVLIWEKSYVYGPIPHTFDRDWVAMQTKRMLDMKANPIQGFSAKWDYDKNEWKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13073-1", "uniprot_id": "COX41_HUMAN", "id": "P13073-1", "name": "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial", "aln": "---------MLATRVFSLVGKRAISTSVC-----VRAHESVVKSEDFSLPAYMD---RRDHPLPEVAHVKHLSASQKALKEKEKASWSSLSMDEKVELYRIKFKES---FAEMNRGSNEWKT--VVGGAMFFIGFTALVIMWQKHYVYGPLPQSFDKEWVAKQTKRMLDMKVNPIQGLASKWDYEKNEWKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91W29-1", "uniprot_id": "COX42_MOUSE", "id": "Q91W29-1", "name": "Cytochrome c oxidase subunit 4 isoform 2, mitochondrial", "aln": "---------MFSRAARSLVMRTG-LRTRGTG---THSPGDAAGS-QRRMTPYVDCYAQRSYPMPDEPFCTELSEEQRALKEKEKGSWTQLSQAEKVALYRLQFHET---FAEMNHRSNEWKT--VMGCVFFFIGFTALVIWWQRVYVFPKKVVTLTEERKAQQLQRLLDMKSNPIQGLAAHWDYEKKEWKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91Y94-1", "uniprot_id": "COX42_RAT", "id": "Q91Y94-1", "name": "Cytochrome c oxidase subunit 4 isoform 2, mitochondrial", "aln": "---------MFSRATRSLVMKTGGLRTQG-----THSPGSAASSSQRRMTPYVDCYAQRSYPMPDEPYCTELSEEQRALKEKEKGSWAQLSQAEKVALYRLQFHET---FAEMNHRSNEWKT--VMGCVFFFIGFTALVIWWQRVYVFPKKVVTLTEERKAQQLQRLLDMKSNPIQGLSAHWDYEKKEWKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96KJ9-1", "uniprot_id": "COX42_HUMAN", "id": "Q96KJ9-1", "name": "Cytochrome c oxidase subunit 4 isoform 2, mitochondrial", "aln": "---------MLPRAAWSLVLRKGGGGRRG-----MHSSEGTTRG-GGKMSPYTNCYAQRYYPMPEEPFCTELNAEEQALKEKEKGSWTQLTHAEKVALYRLQFNET---FAEMNRRSNEWKT--VMGCVFFFIGFAALVIWWQRVYVFPPKPITLTDERKAQQLQRMLDMKVNPVQGLASRWDYEKKQWKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R6I1-1", "uniprot_id": "F1R6I1_DANRE", "id": "F1R6I1-1", "name": "Cytochrome c oxidase subunit 4", "aln": "---------MLSSRALVRGLQSGFWRRLSTSSGIWAAHTHDVDVTDCSVPQYNN---RLDTPLPDVPFVRNLSAEQKKLKEKEKGPWTQLSKEEKLAIYRLTHELS---FPEMRKGSKEWMT--VLAGVFFFLGFTGLLVWWQRVFVYGDVPHTLSQEWIEKQTQRMLDMKVNPITGFAHKWDYEKKQWK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIQ8-1", "uniprot_id": "Q9VIQ8_DROME", "id": "Q9VIQ8-1", "name": "Cytochrome c oxidase subunit 4", "aln": "MALRLLNSAVLRQLASQLPKSAQVGSVAAVHTLDKIGKREIVGYGWNGTACYAD---RVDYPLPAVRFREPTN-EINALRAKEQGDWKKLSTQEIKALYRASFCQT---IAEVQAGSGEWKL--HLGVSLLFCAAAIWVAVLMNIFVYDELPVTFDEEHQKAQLQRIIDLEINPVTGLTSKWDYENKKWKN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00424-1", "uniprot_id": "COX5A_YEAST", "id": "P00424-1", "name": "Cytochrome c oxidase subunit 5A, mitochondrial", "aln": "----------MLRNTFTRAGGLSRITSVR----FAQTHALSNAAVMDLQSRWEN--------MPS----TEQQDIVSKLSERQKLPWAQLTEPEKQAVWYISYGEWGPRRPVLNKGDSSFIAKGVAAGLLFSVGLFAVVRMAG-----GQDAKTMNKEWQLKSDEYLKSKNANPWGGYSQVQSK-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : : :* . * ::: * .*: * :: . . :. .: . :: . : :: : . : : . : ** * : . ", "identical_positions": 8, "similar_positions": 35, "identity": "4.19%" }, { "cls_id": "homologset.agr.SGD:S000004998", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BFV3-1", "uniprot_id": "DUS4_MOUSE", "id": "Q8BFV3-1", "name": "Dual specificity protein phosphatase 4", "aln": "-----------------MVTMEELREMDCSVLKRLMNRDENGGGGSAGGNGSGSHGALGLLSGGKCLLLDCRPFLAHSAGYIRGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGLYSAVIV---YDERSPRAESLREDSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSKTKALAAIPPPVPP-STNESLDLGCSSCGTPLHDQGGPVEILP---------FLYLGSAYHAARRDMLDALGITALLNVSSDCPN-----HFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLTTS-CAAEAASPSGPLRERG---------------------------------------------------------KATPTPTSQFVFSFPVSVGVHAAPSNLPYLHSPITTSPSC----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62767-1", "uniprot_id": "DUS4_RAT", "id": "Q62767-1", "name": "Dual specificity protein phosphatase 4", "aln": "-----------------MVTMEELREMDCSVLKRLMNRDENG--GTAGSSG-GSHGALGLLSGGKCLLLDCRPFLAHSAGYIRGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGLYSAVIV---YDERSPRAESLREDSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSKTKALAAIPPPVPP-STNESLDLGCSSCGTPLHDQGGPVEILP---------FLYLGSAYHAARRDMLDALGITALLNVSSDCPN-----HFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLTTS-CAAEAASPSGPLRERG---------------------------------------------------------KATPTPTSQFVFSFPVSVGVHAAPSNLPYLHSPITTSPSC----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13115-1", "uniprot_id": "DUS4_HUMAN", "id": "Q13115-1", "name": "Dual specificity protein phosphatase 4", "aln": "-----------------MVTMEELREMDCSVLKRLMNRDENG--GGAGGSG--SHGTLGLPSGGKCLLLDCRPFLAHSAGYILGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGLYSAVIV---YDERSPRAESLREDSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSKTKALAAIPPPVPP-SATEPLDLGCSSCGTPLHDQGGPVEILP---------FLYLGSAYHAARRDMLDALGITALLNVSSDCPN-----HFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATS-CAAEAASPSGPLRERG---------------------------------------------------------KTPATPTSQFVFSFPVSVGVHSAPSSLPYLHSPITTSPSC----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PEI8-1", "uniprot_id": "A0A8M1PEI8_DANRE", "id": "A0A8M1PEI8-1", "name": "Dual specificity protein phosphatase", "aln": "--------------MYLELSFCTMVIMEVPTIDSASLRDMLE-----GDDP-------------DCLVLDCRSFFSFSVSHISGSSNVRFSTIVRRRARGGLGLEHIVP-NEDTRNRLLSGEYQSVVF---LDDHSLEMGEVKKDGTLMLAVNALCRKQCGASVYLLKGGFDTFSAEFPEKCTKTVPPQGLSLPLSSNCHSNTADSSCNTCTTPLYDQGGPVEILP---------FLYLGSAYHASRKDMLDMLGITALINVSSNCPN-----HFEDHYQYKSIPVEDNHKANISSWFNEAIEFIDSVRNKGGRVFVHCQAGISRSATICLAYLMRTNRVKLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLASSTCSSEAGSP--------------------------------------------------------------------AIGKNSTVFNFP----VHTAASPLSFLQSPITTSPSC----------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAB0-1", "uniprot_id": "Q9VAB0_DROME", "id": "Q9VAB0-1", "name": "Protein-tyrosine-phosphatase", "aln": "---------------------------------------------------------------------------------------------MQELIVGGIAISGVPFANETVEKESRQNQLSASTL---EDHTP-----------------------------------------FP----------------------------------------GLSRITP---------SLILCGAAAVVP-AYMDKLGVSCVINVAPELPDTP--LPSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQLRGSS----------------------------------------------------------------------------SVAMVYFASLDKEIPDILEPEYRAMEDFYQRYRSSLKRR---------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VHV8-1", "uniprot_id": "Q9VHV8_DROME", "id": "Q9VHV8-1", "name": "protein-tyrosine-phosphatase", "aln": "--------------------MCVNRETQSSSNNNSNNTTTATS---------------------TARNNNSHNGRCECDGDGDSVSHIQSEMKMRIKREAPCLLLFMPIQNTNNNNRIGANQKDYPNK---RSRENLACDEVTSTTSSSTAMNGGGR-------------------------------------------TPALTRSCSSPAVYDIETHPASPVFP---------HLLLGNGRDADD---PSSVGANCVLNVTCQSPNE----SHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNLRKSGVLAPATPHLNSPSNPSSSSVGLSTQSSQLVEQPEEEEKREQRERGKSKSDSEAMDEDGFDYDDVDSGSGSLAGSNCSSRLTSPPITPDDEAPSTSAAASSVSELDSPSSTSSSSGICSLLQSTSSSVSPRAISKPNLLSPTRQLALFKRNSPAKLRLDLESSYAPASPIPNTMPWLSVPSTPVCEEAPDSRINHVASNLTRD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38590-1", "uniprot_id": "MSG5_YEAST", "id": "P38590-1", "name": "Tyrosine-protein phosphatase MSG5", "aln": "MQFHSDKQHLDSKTDIDFKPNSPRSLQNRNTKNLSLDIAALHPLMEFSSPSQDVPGSVKFPSPTPLNLFMKPKPIVLEKCPPKVSPRPTPPSLSMRRSEASIYTLPTSLKNRTVSPSVYTKSSTVSSISKLSSSSPLSSFSEKPHLNRVHSLSVKTKDLKLKGIRGRSQTISGLETSTPISSTREGTLDSTDVNRFSNQKNMQTTLIFPEEDSDLNIDMVHAEIYQRTVYLDGPLLVLPPNLYLYSEPKLEDILSFDLVINVAKEIPNLEFLIPPEMAHKIKYYHIEWTHTSKIVKDLSRLTRIIHTAHSQGKKILVHCQCGVSRSASLIVAYIMRYYGLSLNDAYNKLKGVAKDISPNMGLIFQLMEWGTMLSKNSPGEEGETVHMPEEDDIGNN----------------------------------------------------EVSSTTKSYSSASFRSFPMVTNLSSSPNDSSVNSSEVTPRTPATLTGARTALATERGEDDEHCKSLSQPADSLEASVDNESISTAPEQMMFLP--------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : : . . :. ::**: : *: . .: . : . *. .: ::** .*:****:: :**:* : * :*:: :: : ** .:: ** . : .. . . . ", "identical_positions": 20, "similar_positions": 48, "identity": "3.45%" }, { "cls_id": "homologset.agr.SGD:S000005000", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60931-1", "uniprot_id": "VDAC3_MOUSE", "id": "Q60931-1", "name": "Non-selective voltage-gated ion channel VDAC3", "aln": "------------------------------------------------------------------------------MCNTPTYCDLGKAAKDVFNKGYGFG-MVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLETKYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFV--PNTGKKSGKLKASYRRDCFSLGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTEFGGSIYQKVNERIETSINLAWTAGSNNTRFG----------IAAKYKLDCRTSLSAKVNNASLIGLGYTQTLRPGVKLTLSALIDGKNFNAGGHKVGLGFELEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y277-1", "uniprot_id": "VDAC3_HUMAN", "id": "Q9Y277-1", "name": "Non-selective voltage-gated ion channel VDAC3", "aln": "------------------------------------------------------------------------------MCNTPTYCDLGKAAKDVFNKGYGFG-MVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLETKYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFV--PNTGKKSGKLKASYKRDCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFG----------IAAKYMLDCRTSLSAKVNNASLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGFELEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R1Z0-1", "uniprot_id": "VDAC3_RAT", "id": "Q9R1Z0-1", "name": "Non-selective voltage-gated ion channel VDAC3", "aln": "------------------------------------------------------------------------------MCSTPTYCDLGKAAKDVFNKGYGFG-MVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLETKYKVCNYGLIFTQKWNTDNTLGTEISWENKLAEGLKLTVDTIFV--PNTGKKSGKLKASYRRDCFSVGSKVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLCQNNFALGYKAEDFQLHTHVNDGTEFGGSIYQRVNEKIETSINLAWTAGSNNTRFG----------IAAKYRLDCRTSLSAKVNNASLIGLGYTQSLRPGVKLTLSALVDGKNFNAGGHKVGLGFELEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2BEA1-1", "uniprot_id": "A0A8M2BEA1_DANRE", "id": "A0A8M2BEA1-1", "name": "Non-selective voltage-gated ion channel VDAC3", "aln": "-----------------------------------------------------MSEKGHKQKGSSETCHHCKPKTCANMAVPPAYADLGKSAKDIFSKGYGFG-TVKLDLKTKSQSGVEFTTGGSSNTDTGKAAGNLETKYKVKELGLSLNQKWNTDNVLTTEVTLEDQLTKGLKLGLDTSFV--PNTGKKSAKLKTGYKREYMNVGCDLDFDLAGPTVHAAAVLGYEGWLAGYQMAFDTAKSKLAQNNFALGYKAGDFQLHTNVNDGTEFGGSIYQKVNGQLETAVNLAWTAGSNNTRFG----------IAAKYQLDKDSSVSAKVNNASLVGVGYTQSLRPGVKLTLSALIDAKNFNAGGHKVGMGFELEV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P45880-3", "uniprot_id": "VDAC2_HUMAN", "id": "P45880-3", "name": "Non-selective voltage-gated ion channel VDAC2", "aln": "------------------------------------------------------------------MATHG-QTCARPMCIPPSYADLGKAARDIFNKGFGFG-LVKLDVKTKSCSGVEFSTSGSSNTDTGKVTGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFS--PNTGKKSGKIKSSYKRECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQLHTNVNDGTEFGGSIYQKVCEDLDTSVNLAWTSGTNCTRFG----------IAAKYQLDPTASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSINAGGHKVGLALELEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60930-1", "uniprot_id": "VDAC2_MOUSE", "id": "Q60930-1", "name": "Non-selective voltage-gated ion channel VDAC2", "aln": "------------------------------------------------------------------MAECCVPVCPRPMCIPPPYADLGKAARDIFNKGFGFG-LVKLDVKTKSCSGVEFSTSGSSNTDTGKVSGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFS--PNTGKKSGKIKSAYKRECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRSNFAVGYRTGDFQLHTNVNNGTEFGGSIYQKVCEDFDTSVNLAWTSGTNCTRFG----------IAAKYQLDPTASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSFNAGGHKLGLALELEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21796-1", "uniprot_id": "VDAC1_HUMAN", "id": "P21796-1", "name": "Non-selective voltage-gated ion channel VDAC1", "aln": "------------------------------------------------------------------------------MAVPPTYADLGKSARDVFTKGYGFG-LIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFS--PNTGKKNAKIKTGYKREHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFG----------IAAKYQIDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z2L0-1", "uniprot_id": "VDAC1_RAT", "id": "Q9Z2L0-1", "name": "Non-selective voltage-gated ion channel VDAC1", "aln": "------------------------------------------------------------------------------MAVPPTYADLGKSARDVFTKGYGFG-LIKLDLKTKSENGLEFTSSGSANTETTKVNGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFS--PNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGYEGWLAGYQMNFETSKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFG----------IAAKYQVDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q94920-1", "uniprot_id": "VDAC_DROME", "id": "Q94920-1", "name": "Voltage-dependent anion-selective channel", "aln": "-------------------------------------------------------------------------------MAPPSYSDLGKQARDIFSKGYNFG-LWKLDLKTKTSSGIEFNTAGHSNQESGKVFGSLETKYKVKDYGLTLTEKWNTDNTLFTEVAVQDQLLEGLKLSLEGNFA--PQSGNKNGKFKVAYGHENVKADSDVNIDLKGPLINASAVLGYQGWLAGYQTAFDTQQSKLTTNNFALGYTTKDFVLHTAVNDGQEFSGSIFQRTSDKLDVGVQLSWASGTSNTKFA----------IGAKYQLDDDASVRAKVNNASQVGLGYQQKLRDGVTLTLSTLVDGKNFNAGGHKIGVGLELEA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKP2-1", "uniprot_id": "Q9VKP2_DROME", "id": "Q9VKP2-1", "name": "", "aln": "-----------------------------------------------------------------------------MAAKTPTYPDLGKLARDLFKRGYHPG-IWQIDCKTLTNSGIEFFTTGFASQDNSKVTGSLQSKYKIEDQGLTLTERWNTENWLFGEIMHRDKLAQGLMLAVEAKFQ--PGSNEADGKFKMGYAQDNFNFLADIGLNSE-PILNCSLVVGHKEFLGGVGTEFDVGNTELKGWKVALGWTNETATLHGELKNGDTWLASLFYKASEKIDAGIEVTKGAGGGEAAEGEQQGGDVVVNLGMIYHLEEDALVRAKVNNLVELGLGYEQKLRDGITASISAVLDCNNFKDGNHRFGVGIALQC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04840-1", "uniprot_id": "VDAC1_YEAST", "id": "P04840-1", "name": "Non-selective voltage-gated ion channel 1", "aln": "-------------------------------------------------------------------------------MSPPVYSDISRNINDLLNKDFYHATPAAFDVQTTTANGIKFSLKAKQPVKDGPLSTNVEAKLNDKQTGLGLTQGWSNTNNLQTKLEFAN-LTPGLKNELITSLT--PG-VAKSAVLNTTFTQPFFTARGAFDLCLKSPTFVGDLTMAHEGIVGGAEFGYDISAGSISRYAMALSYFAKDYSLGATLNNEQITTVDFFQNVNAFLQVGAKATMNCKLPNSNVN--------IEFATRYLPDASSQVKAKVSDSGIVTLAYKQLLRPGVTLGVGSSFDALKLSEPVHKLGWSLSFDA", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VKP4-1", "uniprot_id": "Q9VKP4_DROME", "id": "Q9VKP4-1", "name": "Voltage-dependent anion-selective channel", "aln": "MTNMKQRLRNLFRRNKMRARPTTVASDANKEQPEPPKQEPSKQKKTKQDASKQEPPKQEEPEKPPKEVEVEIIPSPTSEGEMPTYFHVGALAKDCLINGFKIG-AWQMHCSTRTDNDFYLNTFGEGYPTMKNVFGGMEVFKEVGN--YSTSLGWFTNNDLLSEIAVRGMNFGSRLYGLLKSTIGTKDEVSFQTKLKCGLERDPVKVELVVPLYNEPLFLGYVLVAPVENWVLGYRTEYNFDEKGFDKHALCLGYNNGRTEVGLKLENFEDLRGSIFQRIGEAWAFAIKTNLYSSENVKQFA----------IGVQYDFQNGTMVKAKLREDSRMGFVYQSKIGENIDVGYHLAFDGVDPIGGAHRIGVSWGFHC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKP3-1", "uniprot_id": "Q9VKP3_DROME", "id": "Q9VKP3-1", "name": "Voltage-dependent anion-selective channel", "aln": "MP-MRERIRNLFRRNKRKR----AASDYLEPHDE--------GGGNVQDNRSAEEDKEEN--------KVEMLPPPPMEGEMPSYFHVGLLAKMCLIHGYTIG-RWKLQCTSKTEKDFYLSSFGEGYPTWNTVYGGLEAYKESGN--FHASLAWLSDGDLLSDLGVHGDGLGGTWSTVLKSMVSYPEGRKFQCKLKCGFDRNPGKVEMYIPIYKEPLLMGYIMMQPVKNYLLGYRTVFNVEDRDFNMHAFCGGYSNDVTEVGLKFENFKALRGSIFQRIGEKWAVALKANLYGNVSAKSVS----------IGGQYEWEPGSMLKAKVRGDSRIGLIFQKKLREDIEVLFHVGFEGSDPINGKHKFGSSWYFNM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * .:. . : ..: . :. : : ... : . :: . : . * . . * .: . . . . :: : . . : . : : * :: . .. .: : .:: .:: . . : :. * : : . **: : . : . : .: .: . *:.* . :. ", "identical_positions": 10, "similar_positions": 78, "identity": "2.67%" }, { "cls_id": "homologset.agr.SGD:S000005004", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAQ1-1", "uniprot_id": "D3ZAQ1_RAT", "id": "D3ZAQ1-1", "name": "Actin-related protein 5", "aln": "--MEANVFRFRDARSAPDPVLEAGPVAFGSQ-----PVPLVLDNGSFQARAGWACPGP------DPGPEPRLQFRAVCARGRGGARG-----GLGPQVGNALGSLEPLRWMLRSPFDRNVPVNLELQELLLDYSFQHLGVSSQGCVDHPIVLTEAVCNPLYSRQMMSELLFECYRIPKVAYGIDSLFSFYHNMPK-NALSSGLVISSGYQCTHILPVLEGRLDAKNCKRINLGGSQAAGYLQRLLQLKYPGHLAAITLSRMEEILQEHSYIAEDYAAELQKWRCPDYYENNVHKMQLPFSSKLLG--STLTAEEKQERRQQQLRRLQELNARRREEKLQLDQERLERLLYVQELLEDGQMDQFHKALIELNMDSPEELQSYIQKLTLAVEQAKQKILQ------------------------------------------------AEANLEVDVVDSKPETPD--------------LEPLEPSLEDVENINDFEPLFSEETPEVEKPQVTTTVQPVFNLAAY-------------------------------------------------------------------------------------------------------HQLFVGTERIRAPEIIFQPSLIGEEQAGIAETLHYVLDRYPKAVQD-------TLVQNVFLTGGNVMYPGMKARVEKELLEMRPFQSSFQVQLASNPVLDAWYGARDWALDHLEDSGAWVTRKDYEEKGGEYLKEHCASNTYVPIRLPKQASRASETQTSGRGSGASGSGAGDQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80US4-1", "uniprot_id": "ARP5_MOUSE", "id": "Q80US4-1", "name": "Actin-related protein 5", "aln": "--MEANVFRFRDARSAPDPVLEAGPVAFGSQ-----PVPLVLDNGSFQARAGWACPGP------DPGPEPRLQFRAVCARGRGGARG-----GPGPQVGNALGSLEPLRWMLRSPFDRNVPVNLELQELLLDYSFQHLGVSSQGCVDHPIVLTEAVCNPLYSRQMMSELLFECYRIPKVAYGIDSLFSFYHNVPK-NALSSGLIISSGYQCTHILPVLEGRLDAKNCKRINLGGSQAAGYLQRLLQLKYPGHLAAITLSRMEEILQEHSYIAEDYGAELQKWQCPDYYENNVHKMQLPFSSKLLG--STLTAEEKQERRQQQLRRLQELNARRREEKLQLDQERLERLLYVQELLEEGQMDQFHKALIELNMDSPEELQSYIQKLTLAVEQAKQKILQ------------------------------------------------AEASLEVDVVDSKPETPD--------------LEPLEPTMEDVENISDFEPLFSEETPEVEKPQVTT-VQPVFNLAAY-------------------------------------------------------------------------------------------------------HQLSVGTERIRAPEIIFQPSLIGEEQAGIAETLHFVLDRYPKAIQD-------TLVQNVFLTGGNVMYPGMKARVEKELLEMRPFQSSFQVQLASNPVLDAWYGARDWALDHLEDSGAWVTRKDYEEKGGEYLKEHCASNTYVPIRLPKQASRASETQTSGRGSSASGSGAG---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H9F9-1", "uniprot_id": "ARP5_HUMAN", "id": "Q9H9F9-1", "name": "Actin-related protein 5", "aln": "--MAANVFPFRDARAAPDPVLEAGPVAHGPL-----PVPLVLDNGSFQVRAGWACPGQ------DPGPEPRLQFRAVCARGRGGARG-----ASGPQVGNALGSLEPLRWMLRSPFDRNVPVNLELQELLLDYSFQHLGVSSQGCVDHPIVLTEAVCNPLYSRQMMSELLFECYGIPKVAYGIDSLFSFYHNKPK-NSMCSGLIISSGYQCTHVLPILEGRLDAKNCKRINLGGSQAAGYLQRLLQLKYPGHLAAITLSRMEEILHEHSYIAEDYVEELHKWRCPDYYENNVHKMQLPFSSKLLG--STLTSEEKQERRQQQLRRLQELNARRREEKLQLDQERLDRLLYVQELLEDGQMDQFHKALIELNMDSPEELQSYIQKLSIAVEQAKQKILQ------------------------------------------------AEVNLEVDVVDSKPETPD--------------LEQLEPSLEDVESMNDFDPLFSEETPGVEKP-VTT-VQPVFNLAAY-------------------------------------------------------------------------------------------------------HQLFVGTERIRAPEIIFQPSLIGEEQAGIAETLQYILDRYPKDIQE-------MLVQNVFLTGGNTMYPGMKARMEKELLEMRPFRSSFQVQLASNPVLDAWYGARDWALNHLDDNEVWITRKEYEEKGGEYLKEHCASNIYVPIRLPKQASRSSDAQASSKGSAAGGGGAGEQA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VEC3-1", "uniprot_id": "ARP5_DROME", "id": "Q9VEC3-1", "name": "Actin-related protein 5", "aln": "---------------------MAG------------KRVLVIDNGSYECRVGWSDSKEPDLRFRNVLTKPRKDRKKEAAASEGSASQTTVEQSAEIQVGNDITNIEAVRAHLKSPFERNVITNWNHQEQIFDYIFTKMGFDGQDKIDHPIILTEALANPNFCRQQMNELLFECYGIPSVSYGIDALYSWKHHQQKQKNISDALIISFGYSTTHVIPVLDGKLQLEHVRRLNVGGYHIITYLFRLMQMKYPVHLNAITISRMEKLVHEHCHIAVDYKEELVQWAQMDYYDEHIMKIQLPYNAVTATN-AMLTAEQKQEKRRELAHRLLDIKKNREQEKLREDEQQLFVYNKLRQLYEQKKLDKFERALQQQQIGTLEDLDSLIATINSRIKRAQERAQSG-----------------------------------------------PRPSKQQERLNKMPKPPEGMSQ-------ADWLAELQGKREKILGRKQARQQQRSEQAKRHTHAAQERMRIISSLAKNEKRRKANGEEEDDGFGMNDNDWD-------------------------------VYKRINRYNDDSDSDADNEKLMQFDKILNHYDANTDGNSNVPPQSAAENYQLHFGVENIRVPEVLFQPSMIGCSEAGLAELIAFVLKLFPAAEQQ-------RLVEHVYLTGGCAQFKGLKERLIKELMEMRPFQSKFAIYESDEPTLSAWLGACVHAGEPTFG-QTLTTRQDHQEHGREFFREHTASNIFYPT--PKD-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53946-1", "uniprot_id": "ARP5_YEAST", "id": "P53946-1", "name": "Actin-related protein 5", "aln": "MSSRDASLTPLKAVVIDDPPLRQTPEPFDEQSAYNPQSPIAIDFGSSKLRAGFVNHAT-----------PTHIFPNALTKFRDRKLN-----KNFTFVGNDTLLDQAVRSQSRSPFDGPFVTNWNLTEEILDYTFHHLGVVPDNGIPNPILLTERLATVQSQRTNWYQILFETYNVPGVTFGIDSLFSFYNYNPS--GNKTGLVISCGHEDTNVIPVVDGAGILTDAKRINWGGHQAVDYLNDLMALKYPYFPTKMSYLQYETMYKDYCYVSRNYDEDIEKILTLENLDTNDVVVEAPFTEVLQPQKTEEELRIQAEKRKETGKRLQEQARLKRMEKLVQKQEEFEYFSKVRDQLIDEPKKKVLSVLQNAGFDDERDFKKYLHSLEQSLKKAQMVEAEDDSHLDEMNEDKTAQKFDLLDIADEDLNEDQIKEKRKQRFLKASQDARQKAKEEKERVAKEEEEKKLKEQQWRETDLNGWIKDKRLKLNKLIKRRKEKLKLRDEMKDRKSQVSQNRMKNLASLAEDNVKQGAKRNRHQATIDNDPNDTFGANDEDWLIYTDITQNPEAFEEALEYEYKDIVELERLLLEHDPNFTEEDTLEAQYDWRNSILHLFLRGPRPHDSENIHEQHQMHLNVERIRVPEVIFQPTMGGQDQAGICELSETILLKKFGSQPGKLSQTSIDMVNNVLITGGNAKVPGLKERIVKEFTGFLPTGTNITVNMSSDPSLDAWKGMAALARNEEQYRKTVISKKEYEEYGPEYIKEHKLGNTKYFED-----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:* ** : *.*: * : .. *** :.:* :***: . .* : * ::** * ::*. :. : :**:*** :.. * ::*** * :* *::***:*:*: : . .*:** *:. *:::*:::* . :*:* ** : ** *: :*** . :: : * : :::.::: :* :: : : : : :: *:. : . : *:*:: :** : :. *** .::.: ::: : .:. .* : :. .::.. : .: :::*: . . . : : : . : . : . . :.: . .* .. :: : .** :*: ...*.**.**::***:: * .:**:.* :* :*::* :*** . *:* *: **: : * :.: : :.:* *.** * * : . ::::::* * *:::** .* ", "identical_positions": 105, "similar_positions": 185, "identity": "13.09%" }, { "cls_id": "homologset.agr.SGD:S000005005", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACW1-1", "uniprot_id": "D4ACW1_RAT", "id": "D4ACW1-1", "name": "Nucleolar protein 1", "aln": "MG--RKLDPTKKEKRGPGRKARKQKGAETELIRFLPAAGDENFKRLSSRARKRAAKRRS-------------GSVEVPKPNK--------------SPGIKTLPGELPK----GAVQVRGKKRPAPIQNS----------------DGDEEEDSEEEDVVTQGELWGSEDSSEDMVDDYGADS--EDEEE--KLLPIER------------AALKQKARDPADG-TQWSEEDTDEDE---GVTPESHPRKDDK--------AEGDLQINVEEEEAFVLPPPRGNISLTGPHAQTPDLQRVHKRIQDIVGVLRDFGAQREEGRSRTEYLSQLQKDLATYYSYGDFLLSKLMELFPLSELIEFLEANEVPRPITLRTNTLKTRRRDLAQALINRGVNLDPLGKWSKSGLVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYIAQLMKNTGVILANDANAERLKSVVGNLHRLGVTNTIVSHYDGRQFPKVVGGFDRVLLDAPCSGTGVISKDPAVKTNKDEKDIQRCAHLQKELLLSAIDSVNAASKTGGYLVYCTCSITVEENEWVVDYALKKR-NVRLVPTGLDFGQEGFTRFRERRFHPTLRATRRFYPHTHNMDGFFIAKFKKFSNSIPQPHSGNSAAGTPTEPDLKGQVTPKSENSSQPTKKAHGAAKAKQQLVGQQHSKKP-FQKMNGISKGPG--------------LPTEPSVPNVQVSARPQESS-LSDVK-----RKRAGKLKQRGPKQ----------SAPPPKVGDLGTPAMQTPSEISATPRPK----SPGKAKKREEVKQELPEQPAKGTASLKEDAAP----------KRLSSPTTAHHSSTRPPPAKRRKSMTKGSSQPLLS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q922K7-1", "uniprot_id": "NOP2_MOUSE", "id": "Q922K7-1", "name": "28S rRNA (cytosine-C(5))-methyltransferase", "aln": "MG--RKLDPTKKEKRGPGRKARKQKGAETELVRFLPAAGDENSKRLSSRARKRAAKRRA-------------GSVDVPKPNK--------------SPGIKTLPGELSK----GAVQARGKKRPAPIQNS----------------DGDEEEDSGEDDVVTQGDLWGSEDSDEDMVDDYGAASNSEDEEE--KLLPIER------------AALKQKAQDATAG-VLWNEEDTDEDEDDDGVSPESHPRKDDK--------AEGDLQINVEDEEAFVLPPAG----ETDQDGQAPDLQRVHKRIQDIVGVLRDFGAQREEGRSRAEYLSRLQKDLATYYSYGDFLLSKLMELFPLSELIEFLEANEVPRPITLRTNTLKTRRRDLAQLLINRGVNLDPLGKWSKSGLVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYIAQLMKNTGVILANDANADRLKSVVGNLHRLGVTNTIISHYDGRQFPKVVGGFDRVLLDAPCSGTGVISKDPAVKTNKDEKDIQRCAHLQKELLLSAIDSVNAASKTGGYLVYCTCSITVEENEWVVDYALKKR-NVRLVPTGLDFGQEGFTRFQARRFHPTLRSTRRFYPHTHNMDGFFIAKFKKFSNSIPQPHAGNSAAATPTEPDLKDQVTPKSENGSQPTKKARGAVKAKQQLLRQPHSKKP-FQKLNGIAKGPG--------------LSTEPSVPDAQVSTRPSQSAGNADVNS---KRKRSEKLKQRGPKWKPSKEAAVPKPSAPSRVEDSGTP-VPTPSEIRAAPRPKDCAPSLGKAKKKQKGKQQLAQQPANGAAPLKEDAVS----------KGPSAPFVSPHSSTRPPPAKRRKSMTKGNSQPLLS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46087-1", "uniprot_id": "NOP2_HUMAN", "id": "P46087-1", "name": "28S rRNA (cytosine(4447)-C(5))-methyltransferase", "aln": "MG--RKLDPTK-EKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRRL-------------GSVEAPKTNK--------------SPEAKPLPGKLPKGISAGAVQTAGKKGPQSLFNAPRGKKRPAPG----SDEEEEEEDSEEDGMVNHGDLWGSED-DADTVDDYGADSNSEDEEEGEALLPIER------------AARKQKAREAAAG-IQWSEEETEDEEEEKEVTPESGPPKVEE--------ADGGLQINVD-EEPFVLPPAG----EMEQDAQAPDLQRVHKRIQDIVGILRDFGAQREEGRSRSEYLNRLKKDLAIYYSYGDFLLGKLMDLFPLSELVEFLEANEVPRPVTLRTNTLKTRRRDLAQALINRGVNLDPLGKWSKTGLVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYMAQLMKNTGVILANDANAERLKSVVGNLHRLGVTNTIISHYDGRQFPKVVGGFDRVLLDAPCSGTGVISKDPAVKTNKDEKDILRCAHLQKELLLSAIDSVNATSKTGGYLVYCTCSITVEENEWVVDYALKKR-NVRLVPTGLDFGQEGFTRFRERRFHPSLRSTRRFYPHTHNMDGFFIAKFKKFSNSIPQSQTGNSETATPTNVDLP-QVIPKSENSSQPAKKAKGAAKTKQQLQKQQHPKKASFQKLNGISKGADSE------------LSTVPSVTKTQASSSFQDSSQPAGKAEGIREPKVTGKLKQRSPKLQSSKKVAFLRQNAPPKGTDTQTPAVLSPSKTQATLKPKDHHQPLGRAKGVE--KQQLPEQPFEKAAFQKQNDTP----------KGPQPPTVSPIRSSRPPPAKRKKSQSRGNSQLLLS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P6F7-1", "uniprot_id": "A0A8M1P6F7_DANRE", "id": "A0A8M1P6F7-1", "name": "", "aln": "MG--RKLDPTIKVKRGPGRKARKQKGAETELSKFL--ADDEGPKKLSSRARKRAAKRAQ-------------VTNQLKEPKQ--------------EEKPKKGFSDENKEWLKPAQRKRKIEQSEEDEDSDSQWE---------DDDDDDDDDVDNEQTFDHKDIKNEDDDDKDMVDDYGADEGDEKDSDGEELLPIEK------------AARKQKKQTSMKPESDDDDDEEEEEEDDDDYKEEEKDDSEEE--------EEDTVQANIDTTEKFKLPGAAD---RAKEGLLPMDLKTIHQRIKDNVDVLSNFNEKREEGKERSEYLSLLRADLCTYYSYNQFLISKLMDLFSLSELIDFLEANEVHRPVTIRTNTLKTRRRDLAQALINRGVNLDPLGKWSKVGLVIYDSSVPIGATPEYLAGHYMLQGASSFLPVMALSPQEGESVLDMSAAPGGKTTYMAQLMRNTGMIVANDANVDRLKSVVGNIHRLGVTNAVICNYDGRQFPKVMGGFDRVLLDAPCSGTGVISKDPAVKTGKDEADILRSAHLQKELILSAIDSVNADSQTGGYLVYCTCSIMVEENEWVVDYALKKR-NVKLVPTGLDFGKEGFTRFKEKRFHPSLKLSRRFYPHSHNMDGFFVAKLKKLSNTIPTAP-------------------KETENQEESLVMETAASSEMKEQKPASTPEKSSFEKKQKLNPQTS-----------------KPLIVKKKAEN------------------------KKTGPKK-----------AKIAKLDSEAAKKFEKPSKKQK-----------GKQMNGNPTTEGIKEK-KEGSPFKKKENKT----------KKKNLLKKKKNRMGKNKFKKLKSMLGQQESGQ------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z909-1", "uniprot_id": "A1Z909_DROME", "id": "A1Z909-1", "name": "SAM-dependent MTase RsmB/NOP-type domain-containing protein", "aln": "MG--RKAEYSEKPKKGPGRKARKQGPPVFRKQSFAPMEEED--KKLSHRQKQRFVKREQKKVVQKAKLQEKRAKGKLPQPAKRKTAYNSDSDPEDNEEEPQVASSDEEVPQLVPAPKGQKATAPKGFTDDNDAWLKPKKQQKQPETESEEEEEEDEESEEDSEDELGEECEEEEEGDDEEGLESDDDTAQVGKLADLSDDDDANSDDDFDISGEEDGAQADSDEEEDEDDDDDDDDDDDDKLPIERANKKLKKREAEEAQLADDEMLETVDKQDVFQLPVEG------EETEKDLTLQEVQQRIKDVSLVLSDFKRYRQADRSRGEYIDLLRRDLCLYYSYNEFLMEKLMDMLPLTELMEYLEASEIARPLTIRTNTLKTRRRDLAGALINRGVNLDPLGKWTKVGLVVFNSQVPLGATPEYLAGHYMIQGASSLLPVMALAPQENERILDMCSAPGGKGSHIASIMKNTGVLFANDSNRDRIKAIVANFHRLGIVNAVVSCEDGTKFRNIMTGFDRVLLDAPCTGTGVVSKDPSVKTTKSEVDVQRCYNLQRKLLLTAIDCTDAKSSTGGYIVYSTCSVLPEENEWVIDYALKKR-NVKLVPTGLDFGVEGFTKFRQHRFHPSLNLTKRYYPHTHNMDGFYVAKLKKFSNTIPITKEQQEEDEKQLDEAIEADATTEAAAESEEVEEEVASKEKGPRKLLGKRAGKPSFTEIEQELKKKKREESKTKYVAKVFEQPVKKPKPEKPAEKKNEKSQAPDKQTNSSESPSKSAPKQKQTNGKTTVSNSDAKSFNKKNKGSQPKENGAGSPAKPDDNKPTTNGTNSPSKSAIKETKTKPQPKGKQSPKGNAKLAKAPRVDIDDVPILEGKPIKKQNKLKQKSKQIGQLKKSTAGANAGKKQKFKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40991-1", "uniprot_id": "NOP2_YEAST", "id": "P40991-1", "name": "25S rRNA (cytosine(2870)-C(5))-methyltransferase", "aln": "MGSRRHKNKQAAPPTLEEFQARKEKKANRKL---------EKGKRPSTTQGDEVSDRKK----------------KKSKPFKK-------------SRKEEEEVVEEDKDLPEVDLEELSKARKSLFDDE----------------EDDDEAGLVDEELKDEFDLEQEYDYDEDEDNDAHPIFSDDDDEADLEELNAQN----------------------MEALSKKLDEEEAEEAEEAEMELVEAENMQPR----------ADILPTEEQEEMMAQ--------------ETPNLTSTRTRMIEIVKVLENFKTLGAEGRSRGEYVDRLLKDICEYFGYTPFLAEKLFNLFSPAEAMEFFEANEIARPITIRTNTLKTRRRDLAQTLVNRGVNLQPIGSWTKVGLQIFDSQVPIGATPEYLAGHYILQAASSFLPVIALDPHENERILDMAAAPGGKTTYISAMMKNTGCVFANDANKSRTKSLIANIHRLGCTNTIVCNYDAREFPKVIGGFDRILLDAPCSGTGVIGKDQSVKVSRTEKDFIQIPHLQKQLLLSAIDSVDCNSKHGGVIVYSTCSVAVEEDEAVIDYALRKRPNVKLVDTGLAIGKEAFTSYRGKKFHPSVKLARRYYPHTYNVDGFFVAKFQKIGPSS------------------------FDDNQASAKEKETAARKEALEEG-IIHSDFATFEDEE-------------------DDKYIEKSVKN-----------------------------------------------NLLKKGVN---PKAKRPSNEK------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *: : :***: . . : *: * .. .* . :. : . : . . : : ::: :: : . . : :* :. . ::: :: . : . : : : * : *: : :* :* .:.* **:. * *:. *:.* ** **::::. :* ::::**.*: **:*:************* *:******:*:*.*:* ** :::*.**:***********::*.***:***:** *:* * :***..***** :::: :*:*** :.***:* .* *:::.*:**** .*:::. *. :* ::: ****:******:****:.** :**. : * *. : :**::*:*:***..:. *. ** :**.***: **:* *:****:** **:** *** :* *.** :: ::***::. ::*:***::*:***::**::*:. : . .: . . . . * . : . : . *:: ", "identical_positions": 182, "similar_positions": 179, "identity": "20.18%" }, { "cls_id": "homologset.agr.SGD:S000005006", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZVK3-1", "uniprot_id": "D3ZVK3_RAT", "id": "D3ZVK3-1", "name": "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "aln": "------------MELSAAEQPSPQPPHLGDHCIHDGDFVVLKREDVF-------------------KAVQVQRRKKVTFEKQWFYLDNAIGHSYGSTFEVSSGGSLQLR-KKLEEPTSETKEAGTDNRNIVDDG-KSQKLTQDDIKALKDKGIKGEEIVQQLIENSTTFRDKTEFAQDKYIKKKKKKYEAIITILKP-STRILSIMYYAREPGKINHMRYDTLAQMLTLGNIRAGNKMIVMETCSGLVLGAMMERMGGFGSIIQLYPGDGPVRAATACFGFPKSFLSGLHEFPLNKVKSLLNGTFSAEMLSSEPKDSTPVKESNGEL-EKEIAEQADKDSIADGPESN--AEQNPVDIVPGDPESKEPKEKGSKRDY-IQEKQRRQEEQRKRHMEAAALLGERNADGLIVASRFHPTPLLLSLLDFVAPSRPFVVYCQYKEPLLECYTKLRERGGVINLRLSETWLRNYQVLPDRSHPKLLMSGGGGYLLSGFTVVSDSHRVDPSLKSCASALDSPKTEEPAAKKQKCMESAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CE96-1", "uniprot_id": "TRM6_MOUSE", "id": "Q8CE96-1", "name": "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "aln": "------------MEASAAEQPSSPPPPLGDHCIHDGDFVVLKREDVF-------------------KAVQVQRRKKVTFEKQWFYLDNAIGHSYGSAFDVSSGGSLQLR-KKLEEPASETKEAGTDNRNIVDDG-KSQKLTQDDIKALKDKGIKGEEIVQQLIENSTTFRDKTEFAQDKYIKKKKKKYEAIVTILKP-STRILSIMYYAREPGKINHMRYDTLAQMLTLGNIRAGNKMIVMETCSGLVLGAMMERMGGFGSIIQLYPGDGPVRAATACFGFPKSFLSGLYEFPLNKVNSLLNGTFSAEMLSSEPKDSTPVEESNGELEEKEIAEQADEDNIVDAAENNS-GEQRPMEIVPGDPENKEPKEKRSKRDY-IQEKQRRQEEQRKRHLEAAALLGERNADGLIVASRFHPTPLLLSLLDFVAPSRPFVVYCQYKEPLLECYTKLRERGGVINLRLSETWLRNYQVLPDRSHPKLLMSGGGGYLLSGFTVVSDSLRADPSLKSCTGALDPHKAEEPAAKKQKCMESAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJA5-1", "uniprot_id": "TRM6_HUMAN", "id": "Q9UJA5-1", "name": "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "aln": "------------MEGSG-EQPGPQPQHPGDHRIRDGDFVVLKREDVF-------------------KAVQVQRRKKVTFEKQWFYLDNVIGHSYGTAFEVTSGGSLQPK-KKREEPTAETKEAGTDNRNIVDDG-KSQKLTQDDIKALKDKGIKGEEIVQQLIENSTTFRDKTEFAQDKYIKKKKKKYEAIITVVKP-STRILSIMYYAREPGKINHMRYDTLAQMLTLGNIRAGNKMIVMETCAGLVLGAMMERMGGFGSIIQLYPGGGPVRAATACFGFPKSFLSGLYEFPLNKVDSLLHGTFSAKMLSSEPKDSALVEESNGTLEEKQASEQENEDSMAEAPESNHPEDQETMETISQDPEHKGPKERGSKKDY-IQEKQRRQEEQRKRHLEAAALLSERNADGLIVASRFHPTPLLLSLLDFVAPSRPFVVYCQYKEPLLECYTKLRERGGVINLRLSETWLRNYQVLPDRSHPKLLMSGGGGYLLSGFTVAMDNLKADTSLKSNASTLESHETEEPAAKKRKCPESDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N890-1", "uniprot_id": "A0A8M1N890_DANRE", "id": "A0A8M1N890-1", "name": "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "aln": "------------MAECVNDSDE-------DSRIAYGDYVVLKRGEVF-------------------KSVQVENKKKVIFEKQWFFMDNAVGQLYGTMFEIVAGGSLKHKPVKRAGDSLDSKEAGQDNRHIVDDG-RSQKLTRDDIETLKEQGLKGQEIVQQLIDNSTTFKDKTEFAQEKYIKKKKKKYESDITVLKP-STRLLAMMYHGREPGKICHLRYDTLAQMLTLGNIHAGSKIIVFETCAGLVLGSVMERMGGFGSVIQMFPGGGPTRAGMESFGFPSHFHQTLHEFPLCKVNAVLAGKL--------------------DLSEKDTENSRSEE---TAAEKNS--EAQSMEISLDPQEQMRIAERDRLRELRAQEKKVKMEEKRKKLASAAALLQDRNADGLVIASRFHPCPVLMGLLKFVAPSRPFVVYCQYREPLIECYNKLREQGGVINLRLTDSWLRHYQVLPNRTHPVLLMSGGGGYLLSGTTVDAGTAKTKNPHKSEEPDAKRLKLEEKASS---CDSSV-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41814-1", "uniprot_id": "TRM6_YEAST", "id": "P41814-1", "name": "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "aln": "MNALTTIDFNQHVIVRLPSKNYKIVELKPNTSVSLGKFGAFEVNDIIGYPFGLTFEIYYDGEEVSSDENRDSKPKNKIPIGKVRLLSQEIKDVNNDKDDGQSEPPLSIK-EKSVSLELSSIDSSATNQNLVNMGSKAQELTVEEIEKMKQESLSSKEIIDKIIKSHKSFHNKTVYSQEKYVNRKKQKFAKYFTVEYLSSSNLLQFLIDKGDIQRVLDMSQESMGMLLNLANIQSEGNYLCMDETGGLLVYFLLERM---------FGGDNESKSKGKVIVIHENEHANLDLLKFANYS------------------------------EKFIKEHVHTISLLDFFEPPT-LQEIQSRFTPLPKEEARALKGGKKNSY------YRKLRWYNTQWQILELTGEFLYDGLVMATTLHLPTLVPKLAEKIHGSRPIVCYGQFKETLLELAHTLYSDLRFLAPSILETRCRPYQSIRGKLHPLMTMKGGGGYLMWCHRVIPAPEPVSENATAADS---SEKLAEHGAKKQKI-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. : : *.: .:: ::: . : .. *: : :.: : . . : : .*. : * .: ::. *:::*: * ::*:** ::*: :*::.:..:**::::*.. .:*::** ::*:**:::**:*: .*: *:.:* :: : :: .: :::. :*.*.**:: .: : :: .**:: ::*** : *.. :: : : . * : : : . ** : * : * : .. : . : . * : ***::*: :* .:: * . : ***:* * *::*.*:* .* . .: : :: * ** : .: ** : *.******: * .. .: : * .:. ", "identical_positions": 73, "similar_positions": 159, "identity": "13.7%" }, { "cls_id": "homologset.agr.SGD:S000005007", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q921L7-1", "uniprot_id": "HEMK1_MOUSE", "id": "Q921L7-1", "name": "MTRF1L release factor glutamine methyltransferase", "aln": "MKLWGQILWTLLSVPRGRRGVLQGWAFNSWKTYSSLTGPLSATGMVNHWTRVFEERGIPEARESSEYIVAHVLGAKTFQSLKPALWTKPLTPQQLECIQELCGRRLQRMPVQYILGEWDFQGLSLKMVPPVFIPRPETEELVEWVLEEVAQRPHAVRAQDGPLILEVGCGSGAITLSLLSQLPKSRVVAVDKEEAAVSLTHENAQRLQLQDRIRIIHLDITSEGCCTHLLPWSPLDLVVSNPPYIFRKDM-EQLAPEICSYEDLVALDGGDEGMDIITHILTLAPQLLNASGSIFLEVDPRHPELVSSWLQSHPDLHLS---LVGVREDFCGRPRFLHVQKSAP------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5R4-1", "uniprot_id": "HEMK1_HUMAN", "id": "Q9Y5R4-1", "name": "MTRF1L release factor glutamine methyltransferase", "aln": "MELWGRMLWALLSGP-GRRGSTRGWAFSSWQPQPPLAGLSSAIELVSHWTGVFEKRGIPEARESSEYIVAHVLGAKTFQSLRPALWTQPLTSQQLQCIRELSSRRLQRMPVQYILGEWDFQGLSLRMVPPVFIPRPETEELVEWVLEEVAQRSHAVGSPGSPLILEVGCGSGAISLSLLSQLPQSRVIAVDKREAAISLTHENAQRLRLQDRIWIIHLDMTSERSWTH-LPWGPMDLIVSNPPYVFHQDM-EQLAPEIRSYEDPAALDGGEEGMDIITHILALAPRLLKDSGSIFLEVDPRHPELVSSWLQSRPDLYLN---LVAVRRDFCGRPRFLHIRRSGP------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VMD3-1", "uniprot_id": "Q9VMD3_DROME", "id": "Q9VMD3-1", "name": "peptide chain release factor N(5)-glutamine methyltransferase", "aln": "------MLRQLTRSMGPTSRLLKQVNYGTNAPAGTHIPVTKALEIG-QWEEKLKAAGVEDRKFNVKCIVSHVLKQK-FSSVPDSFDQLQLNPGQLADFERFLEARCARMPLQHIIGEWDFMDITLKTSPSVFIPRPETEEFMRLVIDDHKNAKHVD-------LLEVGCGSGAMSLSMLHSLPQVVATAIERSKAATVLAAENAKMLGLLNRFEVHNHTMEEDKYLPEALKDKKYDLIISNPPYVKTEEF-QFLHPEVVVYENLNALDGGSDGLRVARLVFDLACRHLRPGGKLWLELGNDHPPMVKTIMNLKYEGRLK---FIAGYSDQYQRERFVQIEKV--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53944-1", "uniprot_id": "MTQ1_YEAST", "id": "P53944-1", "name": "Mitochondrial MRF1 N(5)-glutamine methyltransferase MTQ1", "aln": "-----------------MPRISTSLIRKASRIRPGLHLLLP------------ECRTLEQAKLEYKWLTEELPPDK--------------------SIRWACLQRYKHVPLQYILRSQPFGALDIVCKPGVLIPRWETEEWVMAIIRALNN-SMLSRHTIPLHICDTFTGTGCIALALSHGIANCTFTAIDVSTRAIKLVKENMLKNKVSGGKLVQHNILSSKASDEY---PSHIDILTGNPPYIRKRDFNRDVKTSVKLFEPRLALVG------ELECYINLVNYWLPKTDSFFYEIG-DVEQFNYVERRIKEDSYLSRIWSIGLKYDSNGKARVVYGFKATPKGRILHQIFASFGTIRHLATALSGHKANCN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : : . : :. .: * :. * ::*:*:*: . * : : * *:*** **** : :: : : :. *:*.::*:: :.: *:: * *. ** : . : : : .. *:: .****: .:: . : ..: :* ** * : *. * ..:: *:. : . : : *. :. * : *.: : ", "identical_positions": 38, "similar_positions": 80, "identity": "10.16%" }, { "cls_id": "homologset.agr.SGD:S000005008", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63036-1", "uniprot_id": "DNJA1_RAT", "id": "P63036-1", "name": "DnaJ homolog subfamily A member 1", "aln": "--MVKETTYYDVLGVKPNATQEELKKAYRKLALKYHPDKNPNE--GEKFKQISQAYEVLADSKKRELYDKGGEQAIK-EGGAGG----GFGSPMDIFDMFFGG-----GGRMQRER----RGKNVVHQLSVTLEDLYNG-ATRKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQSVCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGDQEPGLEPGDIIIVLDQKDHAVFTRRGEDLFMC-MDIQLVEALCGFQKPISTLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYEKGRLIIEFKVNFPENGFLSPDKLSLLEKLLPERKEVE--ETDEMDQVELVDFDPNQERRRHYNGEAYED---DEHHPR--GGVQCQTS----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63037-1", "uniprot_id": "DNJA1_MOUSE", "id": "P63037-1", "name": "DnaJ homolog subfamily A member 1", "aln": "--MVKETTYYDVLGVKPNATQEELKKAYRKLALKYHPDKNPNE--GEKFKQISQAYEVLADSKKRELYDKGGEQAIK-EGGAGG----GFGSPMDIFDMFFGG-----GGRMQRER----RGKNVVHQLSVTLEDLYNG-ATRKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQSVCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGDQEPGLEPGDIIIVLDQKDHAVFTRRGEDLFMC-MDIQLVEALCGFQKPISTLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYEKGRLIIEFKVNFPENGFLSPDKLSLLEKLLPERKEVE--ETDEMDQVELVDFDPNQERRRHYNGEAYED---DEHHPR--GGVQCQTS----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31689-1", "uniprot_id": "DNJA1_HUMAN", "id": "P31689-1", "name": "DnaJ homolog subfamily A member 1", "aln": "--MVKETTYYDVLGVKPNATQEELKKAYRKLALKYHPDKNPNE--GEKFKQISQAYEVLSDAKKRELYDKGGEQAIK-EGGAGG----GFGSPMDIFDMFFGG-----GGRMQRER----RGKNVVHQLSVTLEDLYNG-ATRKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQSVCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGDQEPGLEPGDIIIVLDQKDHAVFTRRGEDLFMC-MDIQLVEALCGFQKPISTLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYEKGRLIIEFKVNFPENGFLSPDKLSLLEKLLPERKEVE--ETDEMDQVELVDFDPNQERRRHYNGEAYED---DEHHPR--GGVQCQTS----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JMC3-1", "uniprot_id": "DNJA4_MOUSE", "id": "Q9JMC3-1", "name": "DnaJ homolog subfamily A member 4", "aln": "--MVKETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDE--GEKFKLISQAYEVLSDPKKRDIYDQGGEQAIK-EGGSGSP---SFSSPMDIFDMFFGG-----GGRMTRER----RGKNVVHQLSVTLEDLYNG-ITKKLALQKNVICEKCEGIGGKKGSVEKCPLCKGRGMQVHIQQIGPGMVQQIQTVCIECKGQGERINPKDRCENCSGAKVTREKKIIEVHVEKGMKDGQKILFHGEGDQEPELDPGDVIIVLDQKDHSVFQRRGQDLIMK-MKIQLSEALCGFKKTIKTLDDRVLVISSKSGEVIKHGDLKCIRNEGMPIYKAPLEKGVMIIQFLVVFPEKQWLSQEKLPQLEALLPPRQKVR--ITDDMDQVELKEFNPNEQSWRQHR-EAYEE---DDEEPR--AGVQCQTA----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WW22-1", "uniprot_id": "DNJA4_HUMAN", "id": "Q8WW22-1", "name": "DnaJ homolog subfamily A member 4", "aln": "--MVKETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDE--GEKFKLISQAYEVLSDPKKRDVYDQGGEQAIK-EGGSGSP---SFSSPMDIFDMFFGG-----GGRMARER----RGKNVVHQLSVTLEDLYNG-VTKKLALQKNVICEKCEGVGGKKGSVEKCPLCKGRGMQIHIQQIGPGMVQQIQTVCIECKGQGERINPKDRCESCSGAKVIREKKIIEVHVEKGMKDGQKILFHGEGDQEPELEPGDVIIVLDQKDHSVFQRRGHDLIMK-MKIQLSEALCGFKKTIKTLDNRILVITSKAGEVIKHGDLRCVRDEGMPIYKAPLEKGILIIQFLVIFPEKHWLSLEKLPQLEALLPPRQKVR--ITDDMDQVELKEFCPNEQNWRQHR-EAYEE---DEDGPQ--AGVQCQTA----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PNG1-1", "uniprot_id": "A0A8M9PNG1_DANRE", "id": "A0A8M9PNG1-1", "name": "", "aln": "--MVRETGYYDQLGVKPDASLDEIKKAYRKLALKYHPDKNPNE--GEKFKLISQAYDVLSDAKKRELYDQGGEQAIK-EGGMAG-----GDSPMDIFNMFFGG-----GGRMQRER----KGKNLVHQLGVTLEELYNG-STRKLALQKNVICQKCDGYGGKKGTVEKCSSCKGSGVQVRVQQIGPGMIQQTQSMCSDCSGQGERFSAKDRCKTCNGRKVERKKKILEVHIDKGMKDGQKITFNGEGDQEPGLEPGDVTIILDLKEHPVFQRKDNNLLMK-MKIRLVEALCGFKKTISTLDNRSLLIHSPPGQVIKPNDLKCVHNEGMPVYREPFEKGLLIIRFEIEFPDDHWLPEHMLPDLERLLPVREHIM--LTDDMEEVDLCQVDFESQQRRNHSAEAYHE---DDEEERRQTGVQCQTQ----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFV9-1", "uniprot_id": "Q9VFV9_DROME", "id": "Q9VFV9-1", "name": "", "aln": "--MVKETGYYDILGVKPNATPDELKKAYRKLALKYHPDKNPNE--GEKFKAISQAYEVLSDADKRQVYDEGGEAAIK-KGGADSG---DFRNPMDFFEKFFGAGFGGSGGGRRRER----RGKDVVHQMSVQLEELYNG-ATRKLQLQKNVICDKCEGRGGKKGSIEKCLQCRGNGVETRVQQIAPGIMQHIEQVCRKCSGTGETIQEKDRCKNCSGRKTVRERKVLEVHIEKGMRDGQKIVFTGEGDHEPESQPGDIIILLDEKEHSTFAHAGQDLMMK-MPLQLVEALCGFQRIVKTLDDRDLIVSTQPGEVIRHEMTKCIAEEGMPIFKNPMEKGTLIIQFEVIFP--EVINPSVVPTLKQCLPPAPEVD--IPIDAEQTVLEDFDP-KQRRQQHQRMAYDE---DDGGYQDGPRVQQCTSS---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9QYJ0-1", "uniprot_id": "DNJA2_MOUSE", "id": "Q9QYJ0-1", "name": "DnaJ homolog subfamily A member 2", "aln": "MANVADTKLYDILGVPPGASENELKKAYRKLAKEYHPDKNPNA--GDKFKEISFAYEVLSNPEKRELYDRYGEQGLR-EGSGGG------GGMDDIFSHIFGGGLFGFMGNQSRSRNGRRRGEDMMHPLKVSLEDLYNG-KTTKLQLSKNVLCSACSGQGGKSGAVQKCSACRGRGVRIMIRQLAPGMVQQMQSVCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILEVHVDKGMKHGQRITFTGEADQAPGVEPGDIVLLLQEKEHEVFQRDGNDLHMT-YKIGLVEALCGFQFTFKHLDARQIVVKYPPGKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELEDLLPSRPEVPN-VIGETEEVELQEFDSTRGSGGGQRREAYNDSSDEESSSHHGPGVQCAHQ----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35824-1", "uniprot_id": "DNJA2_RAT", "id": "O35824-1", "name": "DnaJ homolog subfamily A member 2", "aln": "MANVADTKLYDILGVPPGASENELKKAYRKLAKEYHPDKNPNA--GDKFKEISFAYEVLSNPEKRELYDRYGEQGLR-EGSGGG------GGMDDIFSHIFGGGLFGFMGNQSRSRNGRRRGEDMMHPLKVSLEDLYNG-KTTKLQLSKNVLCSACSGQGGKSGAVQKCSACRGRGVRIMIRQLAPGMVQQMQSVCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILEVHVDKGMKHGQRITFTGEADQAPGVEPGDIVLFVQEKEHEVFQRDGNDLHMT-YKIGLVEALCGFQFTFKHLDARQIVVKYPPGKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELEDLLPSRPEVPN-VIGETEEVELQEFDSTRGSGGGQRREAYNDSSDEESSSHHGPGVQCAHQ----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60884-1", "uniprot_id": "DNJA2_HUMAN", "id": "O60884-1", "name": "DnaJ homolog subfamily A member 2", "aln": "MANVADTKLYDILGVPPGASENELKKAYRKLAKEYHPDKNPNA--GDKFKEISFAYEVLSNPEKRELYDRYGEQGLR-EGSGGG------GGMDDIFSHIFGGGLFGFMGNQSRSRNGRRRGEDMMHPLKVSLEDLYNG-KTTKLQLSKNVLCSACSGQGGKSGAVQKCSACRGRGVRIMIRQLAPGMVQQMQSVCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILEVHVDKGMKHGQRITFTGEADQAPGVEPGDIVLLLQEKEHEVFQRDGNDLHMT-YKIGLVEALCGFQFTFKHLDGRQIVVKYPPGKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELEDLLPSRPEVPN-IIGETEEVELQEFDSTRGSGGGQRREAYNDSSDEESSSHHGPGVQCAHQ----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25491-1", "uniprot_id": "MAS5_YEAST", "id": "P25491-1", "name": "Mitochondrial protein import protein MAS5", "aln": "--MVKETKFYDILGVPVTATDVEIKKAYRKCALKYHPDKNPSEEAAEKFKEASAAYEILSDPEKRDIYDQFGEDGLSGAGGAGGFPGGGFGFGDDIFSQFFGA------GGAQRPR-GPQRGKDIKHEISASLEELYKG-RTAKLALNKQILCKECEGRGGKKGAVKKCTSCNGQGIKFVTRQMGP-MIQRFQTECDVCHGTGDIIDPKDRCKSCNGKKVENERKILEVHVEPGMKDGQRIVFKGEADQAPDVIPGDVVFIVSERPHKSFKRDGDDLVYE-AEIDLLTAIAGGEFALEHVSGDWLKVGIVPGEVIAPGMRKVIEGKGMPIPKYGG-YGNLIIKFTIKFPENHFTSEENLKKLEEILPPRIVPAIPKKATVDECVLADFDPAKYNRTRASRGGANYD--SDEEEQGGEGVQCASQ----------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "M9PD23-1", "uniprot_id": "M9PD23_DROME", "id": "M9PD23-1", "name": "", "aln": "---MDNLNLYDVLKVAPDATDEEIKKNYRKLAKEFHPDKNPDA--GDKFKEISFAYEVLSDPEKRRIYDRYGLKGLQ--EGAEG-----FSDASEFFAQWFPFDR---VSSEGRGR----RNGKVVVKVELTLEEIYVGGMKKKVEYNRQKLCSKCNGDGGPKEAHESCETCGGAGRAAAFTFMG---LSPFDTTCPTCDGRGFTIRDDKKCSPCQGSGFVEQKMKRDLVVERGAPHMLKVPFANEGHQMRGGEFGDLIVVISQMEHPIFQRRHANLYMRDLEINITEALCGYSHCFKHLDGRNVCLRTYPGEVLQHNQIKMVRGSGMPVFNKATDSGDLYMKFKVKFPDNDFATAPQLAMLEDLLPPRQPIV--IPKNAEEVQMTDYKPQPRQQEDEDGQSSHFEGVQCQTAXCMWLWLLQARYLCLDLWLILGTFSVDEVCFLVPLFVLICIVLFFIQECLL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ** * * *: *:** *** * ::******. .:*** * **::*::..** :**. * .: . . ::* * . * * :. .: : **::* * . *: .:: :*. *.* ** . : : * * * * :. :. : * * * * : ..:*. *.* .: :: :: * . :: * .*..: **: ..:. * * : :* : : *:.* . .. :. : : .*::: : : .*** . * : :.* : ** : *: ** :: : : . . . ", "identical_positions": 76, "similar_positions": 105, "identity": "16.38%" }, { "cls_id": "homologset.agr.SGD:S000005009", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14728-1", "uniprot_id": "S75A1_HUMAN", "id": "Q14728-1", "name": "Solute carrier family 75 member 1", "aln": "------------MGWGGGGGCTPRPPIHQQPPERRVVTVVFLGLLLDLLAFT---LLLPLLPGLLESHGRAHDP----------------LYGSWQGGVDW----------FATAIG--------MPVEKRYNS--VLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGISKG-NVSLSTAIVADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAP----WFALLFAASDLLFIFCFLPETLP------------LEKRAPSIALG-------FRDAADLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYT-LSFLTHQRFQFSS----LQQGKMFFLIGLTMATIQGAYARR-------------IHPGGEVAAVKRALLLLVP-------AFLLIGW----GRSLPVLGLGLLLYSFAAAV-VVPCLSSVVAGYG--SPGQKGTVMGTLRS------LGALARAAGPLVAAS--------VYWLAGAQACFTTWSGLFLLPF--------FLLQKLSYPAQTLKAE---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53943-1", "uniprot_id": "AQR1_YEAST", "id": "P53943-1", "name": "Probable transporter AQR1", "aln": "MSRSNSIYTEDIEMYPTHNEQHLTREYTKPDGQTKSEKLNFEGAYINSHGTLSK-TTTREIEGDLDSETSSHSSDDKVDPTQQITAETKAPYTLLSYGQKWGMVAILTMCGFWSSLGSPIYYPALRQLEKQFNVD-ENMVNVTVVVYLLFQGISPTVSGGLADCFGRRPIILAGMLIYVIASIGLACAPSYGVIIFLRCIQSIGISPTIAISSGVVGDFTLKHERGTFVGATSGFVLLGQCFGSLIGAVLTARWDWRAIFWFLTIGCGSCFLIAFLILPETKRTIAGNLSIKPKRFINRAPIFLLGPVRRRFKYDNPDYETLDPTIPKLDLSSAGKILVLPEIILSLFPSGLLFAMWTLMLSSISSG-LSVAPYNYHLVIIGVCYLPGGIGGLMGSFFTGRIIDMYFKRKIKKFEQDKANGLIPQDAEINMFKVRLVCLLPQNFLAVVAYLLFGWSIDKGWRIESILITSFVCSYCAMS-TLSTSTTLLVDLYPTKSSTASSCFNFVRCSLSTIFMGCFAKMKAAMTVGG--------TFTFLCALVFFFNFLMFIPMKYGMKWREDRLLKQQRQSWLNTLAVKAKKGTKRDQNDNHN-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W3W7-1", "uniprot_id": "Q9W3W7_DROME", "id": "Q9W3W7-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "--------------------MIPILEKLSGFYNTYVLAVLTIGYILGELGHYLIGVTSKQTAIELDYGDHACQQN-------------TSMFNRHELPTQCSAVMNETSCYALDFNG-------TGYCEWNYNGLGIDYQILAGPTFILIFTIAGVFMGFAADKYNRVNMLTVCTVIFGIAMILQGTVKEYWQLVILRMIMAAGESGCNPLATGIMSDIFPEDKRALVMAIFNWGIYGGYGIAFPVGRYITKLNFWNLGWRVCYLGAGVLTVIMAALTGTTLR-------------EPERKAIGEG--------DRQTSSGKPVSLWQVIKNPAMIMLMIAASIRHCGGMTFAYNADLYYNTYFPDVDLGWWLFGVTIGIGSVGVVVGGIVSDKIVAKMGIRSRAFVLAVSQLIATLPAFGSVYFDPLWAMITLGLSYFFAEMWFGIVFAIVVEIVP---LRVRSSTIGVFLFVMNNIGGNLPILVDPVAKILGYRGSIMIFYAGFYGISSILFFITCFLLEGKPDEVGQPESPKSHPDAVLNARHMHGHDNSVFSVDETLPSNGRPAQLPQHLQMSSNGYDKSQISPPRQNGAESSRL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : * :. . *: : . : . . * * .:* : .: :: :. . * :* .* :: : : . .: :: * * . . . .:::.::.*: *. :. . . * :. :* :. . : .. :: : * . : * :: :. . : : : : : *. . : * . : : . .. * :.. ::. : : :: :. :. . . : .: . .. : : * *: . : . ", "identical_positions": 21, "similar_positions": 111, "identity": "3.51%" }, { "cls_id": "homologset.agr.SGD:S000005011", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17077-1", "uniprot_id": "RL9_RAT", "id": "P17077-1", "name": "Large ribosomal subunit protein uL6", "aln": "MKT-ILSNQTVDIPENVDITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENG--SLVEIRNFLGEKYIRRVRMRTGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQPDE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LYU5-1", "uniprot_id": "A0ABK0LYU5_RAT", "id": "A0ABK0LYU5-1", "name": "Large ribosomal subunit protein uL6", "aln": "MKT-ILSNQTVDIPENVDITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENG--SLVEIRNFLGEKYIRRVRMRT--------AQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQPDE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32969-1", "uniprot_id": "RL9_HUMAN", "id": "P32969-1", "name": "Large ribosomal subunit protein uL6", "aln": "MKT-ILSNQTVDIPENVDITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENG--SLVEIRNFLGEKYIRRVRMRPGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQADE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P51410-1", "uniprot_id": "RL9_MOUSE", "id": "P51410-1", "name": "Large ribosomal subunit protein uL6", "aln": "MKT-ILSNQTVDIPENVEITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENG--SLVEIRNFLGEKYIRRVRMRTGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQADE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A140T8T4-1", "uniprot_id": "A0A140T8T4_MOUSE", "id": "A0A140T8T4-1", "name": "Large ribosomal subunit protein uL6", "aln": "MKT-ILSNQTVDIPENVEITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFQYKMRSVYAHFPINVVIQENG--SLVEIRNFLGEKYIRRVRMRTGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQADE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AHN0-1", "uniprot_id": "A0A8I6AHN0_RAT", "id": "A0A8I6AHN0-1", "name": "Large ribosomal subunit protein uL6", "aln": "MKTTILSNETVDIPENVDITLKGCTVIVRDPRGTLRRDFNHINVELSLLGKKKKRLCVDKWWGNSKELATVRTICSHVQNMIKGVTLGFCYEMRSVDAHFPINVIIQENG--SLVEIRNFLGEKYIRRVRMRTGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQPDE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZUM9-1", "uniprot_id": "A0A8I5ZUM9_RAT", "id": "A0A8I5ZUM9-1", "name": "Large ribosomal subunit protein uL6", "aln": "--------------------------------------------------------------------------------MIKGVALGFRYKMRSVDAHFPINVVIQENG--SLVEIQNFLGEKYIHGVRMRTGVVCSVSQAQKDELILEGNETELVSNSAALIQQATTVKNKDIRKVLDGIHVSERGTVQQADE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50882-1", "uniprot_id": "RL9_DROME", "id": "P50882-1", "name": "Large ribosomal subunit protein uL6", "aln": "MRT-INSNQCVKIPKDIKASVKARVVTITGTRGTLKRSFKHLALDMYMP--DKRTLKVEKWFGTKKELAAVRTVCSHIENMIKGVTFGFQYKMRAVYAHFPINCVTSENN--TVIEIRNFLGEKYIRRVEMAPGVTVVNSTAQKDELIVEGNDIESVSGSAALIQQSTTVKNKDIRKFLDGLYVSEKTTVVKLES", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P51401-1", "uniprot_id": "RL9B_YEAST", "id": "P51401-1", "name": "Large ribosomal subunit protein uL6B", "aln": "MKY-IQTEQQIEIPEGVTVSIKSRIVKVVGPRGTLTKNLKHIDVTFTKVN--NQLIKVAVHNGDRKHVAALRTVKSLVDNMITGVTKGYKYKMRYVYAHFPINVNIVEKDGAKFIEVRNFLGDKKIRNVPVRDGVTIEFSTNVKDEIVLSGNSVEDVSQNAADLQQICRVRNKDIRKFLDGIYVSHKGFIVEDM-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.**: *: *:** * ****** *:. ..:*::****:* *: * : ***:::.**. * ** .** :** *:******.***::**.: : : ", "identical_positions": 48, "similar_positions": 29, "identity": "24.62%" }, { "cls_id": "homologset.agr.SGD:S000005012", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q02360-1", "uniprot_id": "FOXL1_DROME", "id": "Q02360-1", "name": "Fork head domain-containing protein L1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLPSCYANGSMLP---------------DNE--ELVNSM-LANPDYLRTQVSPN----------------------PLAPSAVGGAG------MEGLM------------CGSFSP------------------------------------------------------------------------------------------------------------AFYYQGIDS--------FLALHN-----------------------------------NIWGLPISFLHNS--------------------------------------HRPEKPPFSYIALIAMAISSAPNQRLTLSGIYKFIMDKFPYYR-ENKQGWQNSIRHNLSLNDCFVKIPRDKNTIEDNDSAGKGSYWMLDSSASDMFEQGNYRRRR---TRRQRHCG-HPNRYERESGK------------------------------------------------------------------------------------------------DSNDGNSSAAEI-RSPSEPLSDFDIFCNERPNYSDRITDLHRQYLSVSLGFNSLFNN-EARGLRPLPEIRECPDDVDASSSSSKAMQSSMELHEELHSPSAFTPPLNRRETSSSGAP---------------VLAEAFNGIKDVVDAPGSSPVASSNRSKTTLFTIDNIIGKP-----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q63248-1", "uniprot_id": "FOXI2_RAT", "id": "Q63248-1", "name": "Forkhead box protein I2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVRPPYSYSALIAMAIQSAPRRRLTLSQIYQYVAGNFPFYK-RTKAGWQNSIRHNLSLNDCFKKVPRD-----END-PGKGNYWMLDPNCEKMFDNGNFRRKR---RRRGE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32031-1", "uniprot_id": "SLP2_DROME", "id": "P32031-1", "name": "Fork head domain transcription factor slp2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MVKIEEGLPSSEISAHSLHFQHHHHPLPPTTHHSALQSP---------------HPVGLNLTNLMKMARTPHLKSSFSIN----------------------SILPETVEHHDEDEEEDVEKKS------------PAKFPP------------------------------------------------------------------------------------------------------------NHNNNNLNTTNWGSPEDHEAESDP---------------------------ESDLDVTSMSPAPVANPNESDPDEVDEEFVEEDIECDGETTDGDAENKSNDGKPVKDKKGNEKPPYSYNALIMMAIRQSSEKRLTLNGIYEYIMTNHPYYR-DNKQGWQNSIRHNLSLNKCFVKVPRH------YDDPGKGNYWMLDPSAEDVFIGGSTGKLR---RRTTAASRSRLAAFKRSLIG------------------------------------------------------------------------------------------------PMFPGLAAYPQFGQFLTYPPTAPSLLASMYQRYNPFAPKGGPGHPGLPPGLPGLPGPPGPQGPPGPPPPPFVAPPTSSELYQRLQYQQLLHQHAAAAALAAHQRQLSVAAASAASQP---------------PPTHHHP-HLAVGQAPLSPGGDSPGPSPQPLHKPVTVVSRNS----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "F1R8Z9-1", "uniprot_id": "FXJ1B_DANRE", "id": "F1R8Z9-1", "name": "Forkhead box protein J1-B", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MPVLMS----PEIANKFKEKWLMLHPEDQ----------------------------------DNVSGSVHFDDSLTS--------------------------LHWLQNFSILSANPERTPS----------------SGCHPQHLF-----------------------------------------------------------------------------------------------------YYKNQLGGTDSPSSPPAGDTAATG-------------------------MPQTPGNPTTSCSSLANPYALQQAGHYITGQT------------------NPAEEIDYKTNRHVKPPYSYATLICMAMQASNKTKITLSAIYSWITENFCYYR-YAEPSWQNSIRHNLSLNKCFMKVPRQ------KDEPGKGGFWQIDPQYADMFVNGVFKRRR----MPATNFNTQRQSKMLSSPS------------------------------------------------------SSYTSQCNQQMGM--GHFQGNKR-KQVFPKRGNKLARISKSPLLTSDIKTSDVLRGDFDLASVFDDVLSGNDSTFEDLDINTALSSLG----------CEMEPSSQIHNQSGYSNEDEQACAYLEANGIIGCNMEDFHHQQHHQQAQVHPQYYEGMFSD----------------QQNQQHPWEIKEEAQPVPLSLDHGYAFCEGFFSEMQ--LWERGESYM----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QDF8-1", "uniprot_id": "FXJ1A_DANRE", "id": "F1QDF8-1", "name": "Forkhead box protein J1-A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MLSMSSMDPWPEGSVGLEEEVVTAAAQAERLDTSTPLQ------------------------CNTSLDSDNLDDSLTS--------------------------LQWLQEFSILNASTGQHTS----------------PSSH-------------------------------------------------------------------------------------------------------------SHLMGSDAPSSPLAGDPASIG-------------------------MPLTPGKPTAASFCRVPMFSALPS---LVAHG------------------HCPDEVDYKSNPHIKPPYSYATLICMAMQASKKTKITLSCIYKWITDNFCYFR-HADPTWQNSIRHNLSLNKCFIKVPRQ------KDEPGKGGFWKIDPQYAERLLNGAYKKRR----LPPVQINPALQHRLRMNAQ------------------------------------------------------ATGVISRNLSVSP--ESQQLLKDFEEATSADQNWDPRLAEATMLSCWISGKGTNKRKQPYNHRTGKTPRRSSSPLLVMDEQEDLSSLRGNFDWDALLDSALNGELSLNEGSPLSPTPQDEELMIRGTHISPQEAPVENHVLMETQRSGDEDFDEETFLA----------------TAFLQSPWSEVDESNRSDFLGSSTVSIDQLFDLSFGGDLSSKIETLL----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3UCQ1-1", "uniprot_id": "FOXK2_MOUSE", "id": "Q3UCQ1-1", "name": "Forkhead box protein K2", "aln": "----------------------------------------------------------------------------------MAAAAALSGAGAPPAGG------------------------------------------------GAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSS---------------QGSVDVSMGHSSFISRRHLEIFTPPGGG-HSAAAPEP--AQPRPDAGGDFYLRCLGKNGVFVDGVFQRRG--APPLQLPRVCTFRFPSTNIKITFTALSSEKREKQEAPESP-----------------------------------------------------------------------------------VKPVQPHISPLTINIPDT-MAHLIS------------------------PLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLSLMAD---NSQPENEKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYR-TADKGWQNSIRHNLSLNRYFIKVPRS------QEEPGKGSFWRIDPASESKLVEQAFRKRR---PRGVPCFRTPLGPLSSRSAP------------ASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGASQPKLAVIQEARFAQSAP--GSPLSSQPVLITVQ-RQLPPAIKPVTYTVATPVTTPTSQPPVVQTVHVVHQIPAVSVTSVAGLAPANTYTVAGQAVVTQAAVLAPPNPEPQENGDHREVRVKVEPVPAISPATLGAASRIIQT-----SQGTPVQTVTIVQQAP---LGQHQLPIKTVTQNGAHVVPMPTAVHSQVNNAAASPLHMLATHASASASLPTKRQNGDQAEQ----------------------------PELKRVKAEDGESIVIALSVDAPPAAVREKAIQN------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A5H3-1", "uniprot_id": "A0A8I6A5H3_RAT", "id": "A0A8I6A5H3-1", "name": "Forkhead box protein K2", "aln": "----------------------------------------------------------------------------------MAAAAALSGAGAPPAGG------------------------------------------------GAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSS---------------QGSVDVSMGHSSFISRRHLEIFTPPGGG-HSAAAPEP--AQPRPDAGGDFYLRCLGKNGVFVDGVFQRRG--APPLQLPRVCTFRFPSTNIKITFTALSSEKREKQEAPESP-----------------------------------------------------------------------------------VKPVQPHISPLTINIPDT-MAHLIS------------------------PLPSPTGTISAANSCPSSPRGAGSSGYKMGRVIPSDLNLMAD---NSQPENEKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYR-TADKGWQNSIRHNLSLNRYFIKVPRS------QEEPGKGSFWRIDPASESKLVEQAFRKRR---PRGVPCFRTPLGPLSSRSAP------------ASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGASQPKLAVIQEARFAQSAP--GSPLSSQPVLITVQ-RQLPPAIKPVTYTVATPVTTPTSQPPVVQTVHVVHQIPAVAVTSVAGLAPANTYTVAGQAVVTQAAVLAP-KTEPQENGDHREVRVKVEPVPAISPATLGAASRIIQT-----SQGTPVQTVTIVQQAP---LGQHQLPIKTVTQNGTHVVPMPTAVHSQVNNAVASPLHMLATHASASASLPTKRQNGDQAEQ----------------------------PELKRVKAEDGESIVIALSVDAPPAAVREKAIQN------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01167-1", "uniprot_id": "FOXK2_HUMAN", "id": "Q01167-1", "name": "Forkhead box protein K2", "aln": "---------------------------------------------------------------------------------MAAAAAALSGAGTPPAGGGA-------------------------------------------GGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSS---------------QGSVDVSMGHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRG--APPLQLPRVCTFRFPSTNIKITFTALSSEKREKQEASESP-----------------------------------------------------------------------------------VKAVQPHISPLTINIPDT-MAHLIS------------------------PLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLNLMAD---NSQPENEKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYR-TADKGWQNSIRHNLSLNRYFIKVPRS------QEEPGKGSFWRIDPASESKLIEQAFRKRR---PRGVPCFRTPLGPLSSRSAP------------ASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGAAQPKLAVIQEARFAQSAP--GSPLSSQPVLITVQ-RQLPQAIKPVTYTVATPVTTSTSQPPVVQTVHVVHQIPAVSVTSVAGLAPANTYTVSGQAVVTPAAVLAPPKAEAQENGDHREVKVKVEPIPAIGHATLGTASRIIQT-----AQTTPVQTVTIVQQAP---LGQHQLPIKTVTQNGTHVASVPTAVHGQVNNAAASPLHMLATHASASASLPTKRHNGDQPEQ----------------------------PELKRIKTEDGEGIVIALSVDTPPAAVREKGVQN------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P42128-1", "uniprot_id": "FOXK1_MOUSE", "id": "P42128-1", "name": "Forkhead box protein K1", "aln": "-------------------------------------------------------MAEVGEDSGARALLALRSAPCSPVLCAAAAAAAFPATTSPPPPAQP--PPGPPALPAEPGP-GPVP-----------STVATATTTAPALVAAAAASVRQSPGPALARLEGREFEFLMRQPSVTIGRNSS---------------QGSVDLSMGLSSFISRRHLQLSFQEP----------------------HFYLRCLGKNGVFVDGAFQRRG--APALQLPQQCTFRFPSTAIKIQFTSLY----HKEEAPASP-----------------------------------------------------------------------------------LRPLYPQISPLKIHIPEPDLRSLVS------------------------PIPSPTGTISVPNSCPASPRGAGSSSYRFVQNVTSDLQLAAEFAAKAASEQQADASGGDSPKDESKPPYSYAQLIVQAISSAQDRQLTLSGIYAHITKHYPYYR-TADKGWQNSIRHNLSLNRYFIKVPRS------QEEPGKGSFWRIDPASEAKLVEQAFRKRR---QRGVSCFRTPFGPLSSRSAP------------ASPTHPGLMSPRSSGLQTPECLSREGSPIPHDPDLGS---KLASVPEYRYSQSAP--GSPVSAQPVIMAVPPRPSNLVAKPVAYMPASIVTS---QQPSGHAIHVVQQAPTVTMVRVVTTSAN---SANGYILASQGSTGTSHDTAGTAVLDLGNEARGLEEKPTIAFATIPAASRVIQTVASQMAPGVPGHTVTILQPATPVTIGQHHLPVRAVTQNGKHAVPTNSLTGNAY--ALSSPLQLLAAQASSSTPVVITRVCEVGPEEPAAAVSVAANAAPTPAASTTTSASSSGEPEVKRSRVEEPGGTATTQPTAMAATGPQGPGTGE------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZU55-1", "uniprot_id": "D3ZU55_RAT", "id": "D3ZU55-1", "name": "Forkhead box protein K1", "aln": "-------------------------------------------------------MAEVGEDSGARALLALRSAPCSPVLCAAAAAAAFPATASPPPPAQP--PPGPPALPAVPGP-EPVP-----------STAATATATAPALVAAAAASVRQSPGPALARLEGREFEFLMRQPSVTIGRNSS---------------QGSVDLNMGLSSFISRRHLQLSFQEP----------------------HFYLRCLGKNGVFVDGAFQRRG--APALQLPQQCTFRFPSTAIKIQFTSLY----HKEEAPASP-----------------------------------------------------------------------------------LRPLYPQISPLKIHIPEPDLRSLVS------------------------PIPSPTGTISVPNSCPASPRGAGSSSYRFVQNVTSDLQLAAEFAAKAASEQQADTSGGDSPKDESKPPYSYAQLIVQAISSAQDRQLTLSGIYAHITKHYPYYR-TADKGWQNSIRHNLSLNRYFIKVPRS------QEEPGKGSFWRIDPASEAKLVEQAFRKRR---QRGVSCFRTPFGPLSSRSAP------------ASPTHPGLMSPRSSGLQTPECLSREGSPIPHDPDLGS---KLASVPEYRYSQSAP--GSPVSAQPVIMAVPPRPSNLVAKPVAYMPASIVTS---QQPSGHAIHVVQQAPTVTMVRVVTTSAN---SANGYILASQGSTATSHDTAGTAVLDLGNEARGLEEKPTIAFATIPAASRVIQTVASQMAPGVPGHTVTILQPATPVTIGQHHLPVRAVTQNGKHAVPTNNLTGNAY--ALTSPLQLLAAQASSSTPVVITRVCEVGPEEPTAAVSVAASAAPTPAISTTTSASSSGEPELKRSRVEEPSGTATTQPTAMAATGPQGPGTGE------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P85037-1", "uniprot_id": "FOXK1_HUMAN", "id": "P85037-1", "name": "Forkhead box protein K1", "aln": "-------------------------------------------------------MAEVGEDSGARALLALRSAPCSPVLCAAAAAAAFPAAAPPPAPAQPQPPPGPPPPPPPPLPPGAIAGAGSSGGSSGVSGDSAVAGAAPALVAAAAASVRQSPGPALARLEGREFEFLMRQPSVTIGRNSS---------------QGSVDLSMGLSSFISRRHLQLSFQEP----------------------HFYLRCLGKNGVFVDGAFQRRG--APALQLPKQCTFRFPSTAIKIQFTSLY----HKEEAPASP-----------------------------------------------------------------------------------LRPLYPQISPLKIHIPEPDLRSMVS------------------------PVPSPTGTISVPNSCPASPRGAGSSSYRFVQNVTSDLQLAAEFAAKAASEQQADTSGGDSPKDESKPPFSYAQLIVQAISSAQDRQLTLSGIYAHITKHYPYYR-TADKGWQNSIRHNLSLNRYFIKVPRS------QEEPGKGSFWRIDPASEAKLVEQAFRKRR---QRGVSCFRTPFGPLSSRSAP------------ASPTHPGLMSPRSGGLQTPECLSREGSPIPHDPEFGS---KLASVPEYRYSQSAP--GSPVSAQPVIMAVPPRPSSLVAKPVAYMPASIVTS---QQPAGHAIHVVQQAPTVTMVRVVTTSAN---SANGYILTSQGAAGGSHDAAGAAVLDLGSEARGLEEKPTIAFATIPAAGGVIQTVASQMAPGVPGHTVTILQPATPVTLGQHHLPVRAVTQNGKHAVPTNSLAGNAY--ALTSPLQLLATQASSSAPVVVTRVCEVGPKEPAAAVAATATTTPATATTASASASSTGEPEVKRSRVEEPSGAVTTPAGVIAAAGPQGPGTGE------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PF47-1", "uniprot_id": "M9PF47_DROME", "id": "M9PF47-1", "name": "", "aln": "MAATTTTTTTTLATTTGNSSSTNNSSSNNNNSIASSHNNNNNIVTVHTVLNNPPTNTAGGGVADAATVAIAKDMLQLHHGAAAAATAALNNYNNSSNNNNNSADQLTGNSNNSANHPPATSSTTN-------SSSSSTTSANTNNPSANAASTLTSSSPPYGELRFNQEVLPITDAVTVIGRNSS---------------TSLVHFNVAENNLVSRKHFQVLYDVELR--------------------AFFVQCLSKNGIFVDDFLQRRN--VDPLRLPQRCYFRFPSTEIRIEFESYVPATSSDAIDGHSPSLVVGGGGGVAGGGAHVIITPLPRDELHQQQLHHHQQQPHLQQQQHPHHPPAHHLPLQQQQQQQQPAHHPLPHTPHHPLHHTALHQQQQRSGSIVVAPPAGAAAHLIAG---DGPGIYSPLKISIPKKEQKSPYLSPTGTISAANSCPASPRQG------FIQNQPNNYNNYGN----NNTQDLFQTPSTASYNHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSLNRYFIKVARS------QDEPGKGSFWRIDPDSGAKLIDHSYKKRR---QRSSQGFRPPYG--MPRSAP------------VSPSHMDNS--------------RESSP-----------------LQDIVLQSAP--GSPGMS------------------LEQRAADPEIIYNSQNAHQQQQQQQQQQQQQTLSNNSNQYSS---GSPYYVTNQSSGVATPQTHVEGSAASGGGGGGGVGALLALKRNHVMGGGASQHTLHQQQAVAQQQHSEIIYEELP--------------TDYSGHIEASEEECVTTATDATVAKRPKYVSEVLXCVRIQKHRQNKGK-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41813-1", "uniprot_id": "FKH2_YEAST", "id": "P41813-1", "name": "Fork head protein homolog 2", "aln": "--------------------------------------------------------MSSSNFNEMNELNMTQTNYGSTKYTAQHHQGVINAIISSLTAPDQ---------------------------------------PTTVSLQYSNDKNMATEIQAYAKLSGPNWTYYVKDLEVSIGRNTDPLNSALQENSDGVKNSYRVNIDLGPAKVVSRKHAIIKYNMNIG--------------------GWELHILGRNGAKVNFQRTHNGPNNPPIRLSSGTLLDIGGTQMMFILPDSDPVVAPICIEHLMPNLINMFG------------------------------------------------------LEGNNNPLLRDIIKQSNYAKQRQLTSNQQIKGFKLYGSGGNAPFGSGANLGPSEQGIFNNNNNSKNKNGYFTSINPNYTASTTTSNTINPQAASPQGPPNTIIAANFVDSYKSSNAYPQALDFTSDLSHDE-NRNVKPPHSYATMITQAILSSPEGVISLADIYKYISSNYAYYR-FAKSGWQNSIRHNLSLNKAFEKVPRR------PNEPGKGMKWRISESYQQEFLNKWNTGKVGKIRRGSSVARQLQLHMAKFNSLPMEMDYRLSLNMAQPPKRQLQSHNVLEPSNNNIIEGFVQHVPSKGNLPASQQSQPPVSHQNQSQQPPPQEQRQEIQFTFADTQNRNIALARPIKTPQLQAPNSNANLNQNNMKEYKESLHPPAISISQMNRQSPNNALVSFTNACANSKIINNISDSADKSTNNNGGTKMNLPAISTSSLDENGNLEPTTTTSSGNSNSVPQTGTTTSSLAANSLRLSQPYDTLLRSPTKAFHITAMEAYTPERGSANRARSPLHSNSNNTNNNGANNSNLQTSGMENKQTGLVLDSNVLKSMESNNDNRRLTPSTSKSQNVKSSPGVWNLLQFSSTNNTPAADSGGNKRGFSINPDIKAKENENATSEKDSDSNSNDLETKDINSSPLKNQGGSTANAKELILDTDGAKISIINN", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A8I6AQ64-1", "uniprot_id": "A0A8I6AQ64_RAT", "id": "A0A8I6AQ64-1", "name": "", "aln": "-----------------------------------------------------------MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKS----------------------------------------------DATQNAHGTGISKKNALLDPNTTLDQEEVQQHKDGKPP-------------------YSYASLITFAINSSPKKKMTLS-----------------------EIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDTLPT------------------------------------------------------------------------------------RPKKRARSVERASTPYSIDSDSLG----------------------MECIISGSASPTLAINTVTNKVTLYNTDQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTNHPEPVSQSLTPQQQ--PQYNLPERDKQLLFTEYNFEDLSASFRSLYKSVFEQSLSQ-QGLMSIPSE-----SSQQSHTSCSYQHSPSSTVTSHPHSNQSSLP-NNH-SGLSATGSNSVAQVSLS---------------------------------------------------------HPQMHTQPSP--HTPHRPHGLPQHPQRPQHPASHPQQHSQLQPPHSQHPPPHQHIQHHPNHQHQTLAHQPPPPPQQVSCNSGVSSDWYATLDMLKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNAQQNVCHGAMHPAKPSQHIGAGNLYIDSRQSGIPPSVMPPPGYPHIPQALNTPGTTMAGHHGAMN----------------------------QQHMMPSQAFQMRRSLPPDDIQDDFDWDSIV-------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BUR3-1", "uniprot_id": "FOXJ3_MOUSE", "id": "Q8BUR3-1", "name": "Forkhead box protein J3", "aln": "-----------------------------------------------------------MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKS----------------------------------------------DATQNAHGTGISKKNALLDPNTTLDQEEVQQHKDGKPP-------------------YSYASLITFAINSSPKKKMTLS-----------------------EIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDTLPT------------------------------------------------------------------------------------RPKKRARSVERASTPYSIDSDSLG----------------------MECIISGSASPTLAINTVTNKVTLYNADQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTNHPEPVSQPLTPQQQQQPQYNLPEREKQLLFTEYNFEDLSASFRSLYKSVFEQSLSQ-QGLMSIPSE-----SSQQSHTSCSYQHSPSSTVTSHPHSNQSSLP-NNH-SGLSATGSNSVAQVSLS---------------------------------------------------------HPQMHPQPSP--HTPHRPHGLPQHPQRPQHPAPHPQQHSQLQPPHSQHPPPHQHIQHHPNHQHQTLAHQPPPPPQQVSCNSGVSSDWYATLDMLKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVPQNVCHGAMHPAKPSQHIGAGNLYIDSRQS-LPPSVMPPPGYPHIPQALNTPGTTMAGHHGAMN----------------------------QQHMMPSQAFPMRRPLPPDDIQDDFDWDSIV-------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPW0-1", "uniprot_id": "FOXJ3_HUMAN", "id": "Q9UPW0-1", "name": "Forkhead box protein J3", "aln": "-----------------------------------------------------------MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKS----------------------------------------------DATQNAHGTGISKKNALLDPNTTLDQEEVQQHKDGKPP-------------------YSYASLITFAINSSPKKKMTLS-----------------------EIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDVLPT------------------------------------------------------------------------------------RPKKRARSVERASTPYSIDSDSLG----------------------MECIISGSASPTLAINTVTNKVTLYNTDQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTSHPESVSQSLTPQQQ--PQYNLPERDKQLLFSEYNFEDLSASFRSLYKSVFEQSLSQ-QGLMNIPSE-----SSQQSHTSCTYQHSPSSTVSTHPHSNQSSLS-NSHGSGLNTTGSNSVAQVSLS---------------------------------------------------------HPQMHTQPSP--HPPHRPHGLPQHPQRSPHPAPHPQQHSQLQSPHPQHPSPHQHIQHHPNHQHQTLTHQAPPPPQQVSCNSGVSNDWYATLDMLKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPTKPSQHIGTGNLYIDSRQN-LPPSVMPPPGYPHIPQALSTPGTTMAGHHRAMN----------------------------QQHMMPSQAFQMRRSLPPDDIQDDFDWDSIV-------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : . :. ::. :.:.** : .:. : . .. : . ", "identical_positions": 3, "similar_positions": 22, "identity": "0.29%" }, { "cls_id": "homologset.agr.SGD:S000005013", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P19253-1", "uniprot_id": "RL13A_MOUSE", "id": "P19253-1", "name": "Large ribosomal subunit protein uL13", "aln": "MA--EGQVLVLDGRGHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLKYLAFLRKRMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALERLKVLDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKRKEKAKMHYRKKKQILRLRKQAEKNVEKKICKFTEVLKTNGLLV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35427-1", "uniprot_id": "RL13A_RAT", "id": "P35427-1", "name": "Large ribosomal subunit protein uL13", "aln": "MA--EGQVLVLDGRSHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLKYLAFLRKRMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALERLKVLDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKRKEKAKIHYRKKKQLLRLRKQAEKNVEKKICKFTEVLKTNGLLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40429-1", "uniprot_id": "RL13A_HUMAN", "id": "P40429-1", "name": "Large ribosomal subunit protein uL13", "aln": "MA--EVQVLVLDGRGHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLKYLAFLRKRMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALDRLKVFDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKRKEKAKIHYRKKKQLMRLRKQAEKNVEKKIDKYTEVLKTHGLLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VNE9-1", "uniprot_id": "RL13A_DROME", "id": "Q9VNE9-1", "name": "Large ribosomal subunit protein uL13", "aln": "MTGLTNRTVVIDGRGHLLGRLASVVAKYLLQGGKVAVVRCEELNLSGHFYRNKIKFLAYLRKRCNVNPARGPFHFRAPSRIFYKAVRGMIPHKTKRGQAALARLRVFDGIPSPYDKRRRVVVPIAMRVLTLRSDRKYCQVGRLSHEVGWHYQDVIKSLERKRKAKLRVTLKHNRELKKLTVKARENIAKAAEPFNKIIKSYGYEV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P26785-1", "uniprot_id": "RL16B_YEAST", "id": "P26785-1", "name": "Large ribosomal subunit protein uL13B", "aln": "MS---QPVVVIDAKDHLLGRLASTIAKQVLNGQKIVVVRAEALNISGEFFRNKLKYHDFLRKATAFNKTRGPFHFRAPSRILYKAIRGMVSHKTARGKAALERLKIFEGIPPPYDKKKRVVVPQALRVLRLKPGRKYTTLGKLSTSVGWKYEDVVAKLEDKRKVRSAEYYAKKRAFTKKVSSASAAASE--SDVAKQLASFGY--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .:*:*.:.*******: :** :* * *:.***.* :*:**.*:***:*: :*** * :***:********:::::***:.*** **:*** **::::***.****::*:*** *::*: *:. **: :*:*: .***:*: * .** *** : ::: : : .* : : : : * ", "identical_positions": 85, "similar_positions": 62, "identity": "41.46%" }, { "cls_id": "homologset.agr.SGD:S000005014", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZMR1-1", "uniprot_id": "D3ZMR1_RAT", "id": "D3ZMR1-1", "name": "Mitochondrial import receptor subunit TOM7 homolog", "aln": "--MVK---LSKEAKQRLQQLFKGGQFAIRWGFIPLVIYLGFTRGAD-PGMPEPSVLSLLWG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D173-1", "uniprot_id": "TOM7_MOUSE", "id": "Q9D173-1", "name": "Mitochondrial import receptor subunit TOM7 homolog", "aln": "--MVK---LSKEAKQRLQQLFKGGQFAIRWGFIPLVIYLGFTRGAD-PGMPEPSVLSLLWG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P0U1-1", "uniprot_id": "TOM7_HUMAN", "id": "Q9P0U1-1", "name": "Mitochondrial import receptor subunit TOM7 homolog", "aln": "--MVK---LSKEAKQRLQQLFKGSQFAIRWGFIPLVIYLGFKRGAD-PGMPEPTVLSLLWG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53507-1", "uniprot_id": "TOM7_YEAST", "id": "P53507-1", "name": "Mitochondrial import receptor subunit TOM7", "aln": "MSFLPSFILSDESKERISKILTLTHNVAHYGWIPFVLYLGWAHTSNRPNFLN--LLSPLPSV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: **.*:*:*:.:::. : . ::*:**:*:***: : :: *.: : :** * . ", "identical_positions": 16, "similar_positions": 27, "identity": "25.81%" }, { "cls_id": "homologset.agr.SGD:S000005015", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BMF4-1", "uniprot_id": "ODP2_MOUSE", "id": "Q8BMF4-1", "name": "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial", "aln": "MWRVCARRARSAVPRDGFRARWAALKEGPGAPCGSPRIGPAAVRCGSGIPRYG-VRSLCGWSSGSGTVPRNRLLRQLLGSPSRRSYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGEKISEGDLIAEVETDKATVGFESLEECYMAKILVPEGTRDVPVGSIICITVEKPQDIEAFKNYTLDLAAAAAPQAAPAAAPAPAAAPAAPSASAPGSSYPTHMQIVLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGAPLCIIVEKQEDIAAFADYRPTEVTSLKPQAAPPAPPPVAAVPPTPQPVAPTPSA----APAGPKGRVFVSPLAKKLAAEKGIDLTQVKGTGPEGRIIKKDIDSFV----------PSKAAPAAAAAMAPPGPRVAPAPA--GVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSVDVNMGEVLLVRKELNKMLEGK-GKISVNDFIIKASALACLKVPEANSSWM--DTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGLETIASDVVSLASKAREGKLQPHEFQGGTFTISNLGMFG-IKNFSAIINPPQACILAIGASEDKLIP-ADNEKGFDVASVMSVTLSCDHRVVDGAVGAQWLAEFKKYLEKPITMLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08461-1", "uniprot_id": "ODP2_RAT", "id": "P08461-1", "name": "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial", "aln": "MWRVCARRVQSAVPRAGFRARWATLK--------GPRTGPAAVRCGSGIPSYG-VRSLCGWSYGSATVPRNRILQQLLGSPSRRSYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGEKISEGDLIAEVETDKATVGFESLEECYMAKILVPEGTRDVPVGSIICITVEKPQDIEAFKNYTLDSATAAT-QAAPAPAAAPAAAPAAPSASAPGSSYPVHMQIVLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKQEDIAAFADYRPTEVTSLKPQAPPPVPPPVAAVPPIPQPLAPTPSA----APAGPKGRVFVSPLAKKLAAEKGIDLTQVKGTGPEGRIIKKDIDSFV----------PTKAAPAAAAA-APPGPRVAPTPA--GVFIDIPISNIRRVIAQRLMQSKQTIPHYYLSVDVNMGEVLLVRKELNKMLEGK-GKISVNDFIIKASALACLKVPEANSSWM--DTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGLETIASDVVSLASKAREGKLQPHEFQGGTFTISNLGMFG-IKNFSAIINPPQACILAIGASEDKLIP-ADNEKGFDVASVMSVTLSCDHRVVDGAVGAQWLAEFKKYLEKPVTMLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10515-1", "uniprot_id": "ODP2_HUMAN", "id": "P10515-1", "name": "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial", "aln": "MWRVCARRAQNVAPWAGLEARWTALQEVPGTPRVTSRSGPAPARRNSVTTGYGGVRALCGWTPSSGATPRNRLLLQLLGSPGRRYYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGDKINEGDLIAEVETDKATVGFESLEECYMAKILVAEGTRDVPIGAIICITVGKPEDIEAFKNYTLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFV----------PSKVAPAPAAVVPPTGPGMAPVPT--GVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGR-SKISVNDFIIKASALACLKVPEANSSWM--DTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFG-IKNFSAIINPPQACILAIGASEDKLVP-ADNEKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITMLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VM14-1", "uniprot_id": "Q9VM14_DROME", "id": "Q9VM14-1", "name": "dihydrolipoyllysine-residue acetyltransferase", "aln": "MLRSLAT------TRNELGALRSVLLRSNNATYVRRSTGNVVVRALSSQLINS--RKLQSIRSKLNTSQSP---VTWSYNFARAYANLPEHIRVPLPALSPTMERGSIVSWEKKEGDKLNEGDLLCEIETDKATMGFETPEEGFLAKILIQGGTKDVPVGQLLCIIVPDQGSVAAFANFKDDGAAAAPAAPAAAPAPAPAAAAAPP---------PP-----------------------------------------------------------------------------------------------------PPPAAAPAAAAPPPAPAAAPAAAG---------TGRVYASPMAKRLAEAQQLRL-QGKGSGVHGSIKSGDLAG-------------QKAAAKPAAAAPAKAPRAAGAR-----YEDIPVTNMRAVIAKRLLESKTQLPHYYVTVQCQVDKLLKFRAKVNKKYEKQGARVSVNDFIIKAVAIASLKVPEANSAWM--DTVIRKYDDVDVSVAVSTDKGLITPIVFNADRKGVLEISKDVKALAAKARDNKLQPHEFQGGTISVSNLGMFG-VNQFAAVINPPQSCILAIGTTTKQLVADPDSLKGFKEVNMLTVTLSADHRVVDGAVAARWLQHFRDYMEDPSNMVL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12695-1", "uniprot_id": "ODP2_YEAST", "id": "P12695-1", "name": "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial", "aln": "--------------------------------------MSAFVRVVPRISRSS-------------------VLTRSLRLQLRCYASYPEHTIIGMPALSPTMTQGNLAAWTKKEGDQLSPGEVIAEIETDKAQMDFEFQEDGYLAKILVPEGTKDIPVNKPIAVYVEDKADVPAFKDFKLEDSGSDSKTSTKAQPAEPQAEKKQE-----------------------------------------------------------------------------------------------------------------APAEETKTSAPEAKKSDVAAPQG-----------RIFASPLAKTIALEKGISLKDVHGTGPRGRITKADIESYLEKSSKQSSQTSGAAAATPAAATSSTTAGSAPSPSSTASYEDVPISTMRSIIGERLLQSTQGIPSYIVSSKISISKLLKLRQSLNATANDK-YKLSINDLLVKAITVAAKRVPDANAYWLPNENVIRKFKNVDVSVAVATPTGLLTPIVKNCEAKGLSQISNEIKELVKRARINKLAPEEFQGGTICISNMGMNNAVNMFTSIINPPQSTILAIATVERVAVEDAAAENGFSFDNQVTITGTFDHRTIDGAKGAEFMKELKTVIENPLEMLL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .* . . * . * * : :*:***** *.:. * ****:::. *:::.*:***** :.** *: ::****: **:*:*:. :.: * . .: ** ::. : : : . .: * .. . * .*. . ::.* . ..:. . *::.**:** :* : : * : :*:* * * . *: . .*. .**. .. . * : *:*::.:* :*.:**::*. :* * :: . .:.::* .* .:* : : ::*:**:::** ::*. :**:**: *: :.***: . *******:* **:**** *.. **: *:.:: *. :** .** *.******: :**:** . :: *:::*****: ****.: : . :**. . :::* : ***.:*** .*.:: .:: :*.* *:*", "identical_positions": 141, "similar_positions": 169, "identity": "21.23%" }, { "cls_id": "homologset.agr.SGD:S000005016", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U209-1", "uniprot_id": "RNH2A_RAT", "id": "Q5U209-1", "name": "Ribonuclease H2 subunit A", "aln": "------------------MDLSELE------------------------RDNTGRCRLSSPVPAVCLKE---PCVLGVDEAGRGPVLGPMVYAICYCPLSRLAD--LEALKVADSKTLTENERERLFAKM---EEDGDFVGWALDILSPNLISTSMLGRV---KYNLNSMSHDTAAGLIQHAMDQNVKVTQVFVDTVGMPETYQARLQQRFPGIEVTVKAKADSLFPVVSAASIIAKVARDQAVKNWQFVESLQGLDSDYGSGYPNDPKTKAWLRKHVDPVFGFPQ-FVRFSWSTAQAILEKEAES---VTWEDSAAEEDPEGPGRITSYFS-QGPQACRPQVSHKYFQERGLETATSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWY8-1", "uniprot_id": "RNH2A_MOUSE", "id": "Q9CWY8-1", "name": "Ribonuclease H2 subunit A", "aln": "------------------MDLSELE------------------------RDNTGRCRLSSPVPAVCLKE---PCVLGVDEAGRGPVLGPMVYAICYCPLSRLAD--LEALKVADSKTLTENERERLFAKM---EEDGDFVGWALDVLSPNLISTSMLGRV---KYNLNSLSHDTAAGLIQYALDQNVNVTQVFVDTVGMPETYQARLQQHFPGIEVTVKAKADSLFPVVSAASIFAKVARDKAVKNWQFVENLQDLDSDYGSGYPNDPKTKAWLRKHVDPVFGFPQ-FVRFSWSTAQAILEKEAED---VIWEDSEAEEDPERPGKITSYFS-QGPQTCRPQAPHRYFQERGLEAASSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75792-1", "uniprot_id": "RNH2A_HUMAN", "id": "O75792-1", "name": "Ribonuclease H2 subunit A", "aln": "------------------MDLSELE------------------------RDNTGRCRLSSPVPAVCRKE---PCVLGVDEAGRGPVLGPMVYAICYCPLPRLAD--LEALKVADSKTLLESERERLFAKM---EDT-DFVGWALDVLSPNLISTSMLGRV---KYNLNSLSHDTATGLIQYALDQGVNVTQVFVDTVGMPETYQARLQQSFPGIEVTVKAKADALYPVVSAASICAKVARDQAVKKWQFVEKLQDLDTDYGSGYPNDPKTKAWLKEHVEPVFGFPQ-FVRFSWRTAQTILEKEAED---VIWEDS-ASENQEGLRKITSYFL-NEGSQARPRSSHRYFLERGLESATSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPP5-1", "uniprot_id": "RNH2A_DROME", "id": "Q9VPP5-1", "name": "Ribonuclease H2 subunit A", "aln": "MSDQEDVVVKKEKKCIENIDENDEEPDDVDFKDSGKISSLKALGPFIAGKENSRNTVYLSDVPDICKDK---PCMLGVDEAGRGPVLGPMVYGISYCPLESNKA--LEDLGCADSKQLTEGKRDIIFNDINTKEYATSCVGWAVEIISPNTISTSMYRRS---KCSLNEVSMDSAMGLIQQAIDAGVNIAEVYVDTVGPPEKYQEKLLKRFPSFKITVAKKADSTYPIVSAASICAKVTRDHALKVWSFPEGLVIKDNEFGSGYPGDPVTRRFLTEYIDLVFGFPR-LVRFSWSTAENALADKAYD---MEFDEPDSEKPKYAGTKLTKFFKGTTKSGEIIREECRFFKQRHLESVMEF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53942-1", "uniprot_id": "RNH2A_YEAST", "id": "P53942-1", "name": "Ribonuclease H2 subunit A", "aln": "------------------MVPPTVEAS----------------------LESPYTKSYFSPVPSALLEQNDSPIIMGIDEAGRGPVLGPMVYAVAYSTQKYQDETIIPNYEFDDSKKLTDPIRRMLFSKIYQDNEELTQIGYATTCITPLDISRGMSKFPPTRNYNLNEQAHDVTMALIDGVIKQNVKLSHVYVDTVGPPASYQKKLEQRFPGVKFTVAKKADSLYCMVSVASVVAKVTRDILVESLKRDP-----DEILGSGYPSDPKTVAWLKRNQTSLMGWPANMVRFSWQTCQTLLDDASKNSIPIKWEEQYMDSRKNAAQKTKQLQL------QMVAKPVRRKRLRTLDNWYR-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :.. * ** .: * ::*:**************.:.*.. : *** * : * :* .: : :*:* ::* ** .* : .**. : * : .**: .:. .*:::.*:***** * .** :* : **..:.** ***: : :**.**: ***:** :: . * *****.** * :* . ::*:* :***** *.: * . : . : ::: .. : .. : * *: ", "identical_positions": 86, "similar_positions": 80, "identity": "23.96%" }, { "cls_id": "homologset.agr.SGD:S000005019", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VHZ7-1", "uniprot_id": "IMP4_MOUSE", "id": "Q8VHZ7-1", "name": "U3 small nucleolar ribonucleoprotein protein IMP4", "aln": "MLRREARLRREYLYRKAREEAQRSVQEKKERVKRALEENQLIPTELRREALALQGSLEFDD---AGGEGVTSHVDDEYR-WAGVEDPKVMITTSRDPSSRLKMFAKELKLVFPGAQRMNRGRHEVGALVRACKANGVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHDIPDLGTMSEAKPHLITHGFSSRLGKRVSDILRYLFPV-PKDDSHRVITFANQDDYISFRHHVYKKTDHRNVELTEVGPRFELKLYMIRLGTLEQEATADVEWRWHPYTNTARKRVFLSAE----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5PQR5-1", "uniprot_id": "IMP4_RAT", "id": "Q5PQR5-1", "name": "U3 small nucleolar ribonucleoprotein protein IMP4", "aln": "MLRREARLRREYLYRKAREEAQRSVQEKKERVKRALEENQLIPTELRREALALQGSLEFDD---AGGEGVTSHVDDEYR-WAGVEDPKVMITTSRDPSSRLKMFAKELKLVFPGAQRMNRGRHEVGALVRACKANGVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHDIPDLGTMSEAKPHLITHGFSSRLGKRVSDILRYLFPV-PKDDSHRVITFANQDDYISFRHHVYKKTDHRNVELTEVGPRFELKLYMIRLGTLEQEATADVEWRWHPYTNTARKRVFLSAE----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96G21-1", "uniprot_id": "IMP4_HUMAN", "id": "Q96G21-1", "name": "U3 small nucleolar ribonucleoprotein protein IMP4", "aln": "MLRREARLRREYLYRKAREEAQRSAQERKERLRRALEENRLIPTELRREALALQGSLEFDD---AGGEGVTSHVDDEYR-WAGVEDPKVMITTSRDPSSRLKMFAKELKLVFPGAQRMNRGRHEVGALVRACKANGVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHDIPDLGTMSEAKPHLITHGFSSRLGKRVSDILRYLFPV-PKDDSHRVITFANQDDYISFRHHVYKKTDHRNVELTEVGPRFELKLYMIRLGTLEQEATADVEWRWHPYTNTARKRVFLSTE----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VBY2-1", "uniprot_id": "Q9VBY2_DROME", "id": "Q9VBY2-1", "name": "Brix domain-containing protein", "aln": "MLRKQARQRREYLYNKALTERLKSKQKIQETVVKSINENKAIGSKNVKKSLTAYKSLKYAD---EGVDDRT--VNDEYH-YAGCEDPKIMLTTSHNPSSRLKMFMKELRLIIPNAQQMNRGNYQLTTLMHACRANNVTDFLIVHEHRGIPDSLVVCHLPYGPTAFFNISDVVMRHDIPDIGHMSEQKPHLIFNNFKTPIGLRTVKILKHLFPV-PKENSQRVMSFLNHNDSIIFRHHQYKYVN-KELELTEVGPRFSLKLYQIKLGTLENIKAADTEWINRPYMNTSQKRLIFSNDPGIINKDTEA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53941-1", "uniprot_id": "IMP4_YEAST", "id": "P53941-1", "name": "U3 small nucleolar ribonucleoprotein protein IMP4", "aln": "MLRRQARERREYLYRKAQELQDSQLQQKRQIIKQALAQGKPLPKELAEDE-SLQKDFRYDQSLKESEEADDLQVDDEYAATSGIMDPRIIVTTSRDPSTRLSQFAKEIKLLFPNAVRLNRGNYVMPNLVDACKKSGTTDLVVLHEHRGVPTSLTISHFPHGPTAQFSLHNVVMRHDIINAGNQSEVNPHLIFDNFTTALGKRVVCILKHLFNAGPKKDSERVITFANRGDFISVRQHVYVRTR-EGVEIAEVGPRFEMRLFELRLGTLEN-KDADVEWQLRRFIRTANKKDYL-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***::** ******.** . *: :: : ::: :.: : .: .. : .:.: : . : *:*** :* **::::***::**:**. * **::*::*.* ::***.: : *: **: ...**::::***** * .* :.*:*.**** *.: :******* : * ** :**** ..*.: :* *. **::** . **.:*.**::* *:.* * .*:* * . . :*::******.::*: ::*****: **.** : : .*:.*: : ", "identical_positions": 108, "similar_positions": 104, "identity": "35.29%" }, { "cls_id": "homologset.agr.SGD:S000005021", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63036-1", "uniprot_id": "DNJA1_RAT", "id": "P63036-1", "name": "DnaJ homolog subfamily A member 1", "aln": "MVKETTYYDVLGVKPNATQEELKKAYRKLALKYHPDKNPNEGE---KFKQISQAYEVLADSKKRELYDKGG---EQAIKEGGAGG---------------------GFGSPMDIFDMFFGG---------------------------------------------GGRMQRERRGKNVVHQLSVTLEDLYNGATRKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQSVCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGDQEPGLE--------PGDIIIVLDQKDHAVFTRRGED--LFMCMDIQLVEALCG-FQKPISTLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYEKGRLIIEFKVNFPENGFLSPDKLSLLEKLLPERKEVEET-------------------DEMDQVELVDFDPN-----------------QERRRHYNGEAYEDDEHHPR--GGVQCQTS-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63037-1", "uniprot_id": "DNJA1_MOUSE", "id": "P63037-1", "name": "DnaJ homolog subfamily A member 1", "aln": "MVKETTYYDVLGVKPNATQEELKKAYRKLALKYHPDKNPNEGE---KFKQISQAYEVLADSKKRELYDKGG---EQAIKEGGAGG---------------------GFGSPMDIFDMFFGG---------------------------------------------GGRMQRERRGKNVVHQLSVTLEDLYNGATRKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQSVCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGDQEPGLE--------PGDIIIVLDQKDHAVFTRRGED--LFMCMDIQLVEALCG-FQKPISTLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYEKGRLIIEFKVNFPENGFLSPDKLSLLEKLLPERKEVEET-------------------DEMDQVELVDFDPN-----------------QERRRHYNGEAYEDDEHHPR--GGVQCQTS-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31689-1", "uniprot_id": "DNJA1_HUMAN", "id": "P31689-1", "name": "DnaJ homolog subfamily A member 1", "aln": "MVKETTYYDVLGVKPNATQEELKKAYRKLALKYHPDKNPNEGE---KFKQISQAYEVLSDAKKRELYDKGG---EQAIKEGGAGG---------------------GFGSPMDIFDMFFGG---------------------------------------------GGRMQRERRGKNVVHQLSVTLEDLYNGATRKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQSVCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGDQEPGLE--------PGDIIIVLDQKDHAVFTRRGED--LFMCMDIQLVEALCG-FQKPISTLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYEKGRLIIEFKVNFPENGFLSPDKLSLLEKLLPERKEVEET-------------------DEMDQVELVDFDPN-----------------QERRRHYNGEAYEDDEHHPR--GGVQCQTS-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JMC3-1", "uniprot_id": "DNJA4_MOUSE", "id": "Q9JMC3-1", "name": "DnaJ homolog subfamily A member 4", "aln": "MVKETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEGE---KFKLISQAYEVLSDPKKRDIYDQGG---EQAIKEGGSGSP--------------------SFSSPMDIFDMFFGG---------------------------------------------GGRMTRERRGKNVVHQLSVTLEDLYNGITKKLALQKNVICEKCEGIGGKKGSVEKCPLCKGRGMQVHIQQIGPGMVQQIQTVCIECKGQGERINPKDRCENCSGAKVTREKKIIEVHVEKGMKDGQKILFHGEGDQEPELD--------PGDVIIVLDQKDHSVFQRRGQD--LIMKMKIQLSEALCG-FKKTIKTLDDRVLVISSKSGEVIKHGDLKCIRNEGMPIYKAPLEKGVMIIQFLVVFPEKQWLSQEKLPQLEALLPPRQKVRIT-------------------DDMDQVELKEFNPN-----------------EQSWRQHR-EAYEEDDEEPR--AGVQCQTA-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WW22-1", "uniprot_id": "DNJA4_HUMAN", "id": "Q8WW22-1", "name": "DnaJ homolog subfamily A member 4", "aln": "MVKETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEGE---KFKLISQAYEVLSDPKKRDVYDQGG---EQAIKEGGSGSP--------------------SFSSPMDIFDMFFGG---------------------------------------------GGRMARERRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKGSVEKCPLCKGRGMQIHIQQIGPGMVQQIQTVCIECKGQGERINPKDRCESCSGAKVIREKKIIEVHVEKGMKDGQKILFHGEGDQEPELE--------PGDVIIVLDQKDHSVFQRRGHD--LIMKMKIQLSEALCG-FKKTIKTLDNRILVITSKAGEVIKHGDLRCVRDEGMPIYKAPLEKGILIIQFLVIFPEKHWLSLEKLPQLEALLPPRQKVRIT-------------------DDMDQVELKEFCPN-----------------EQNWRQHR-EAYEEDEDGPQ--AGVQCQTA-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PNG1-1", "uniprot_id": "A0A8M9PNG1_DANRE", "id": "A0A8M9PNG1-1", "name": "", "aln": "MVRETGYYDQLGVKPDASLDEIKKAYRKLALKYHPDKNPNEGE---KFKLISQAYDVLSDAKKRELYDQGG---EQAIKEGGMAG----------------------GDSPMDIFNMFFGG---------------------------------------------GGRMQRERKGKNLVHQLGVTLEELYNGSTRKLALQKNVICQKCDGYGGKKGTVEKCSSCKGSGVQVRVQQIGPGMIQQTQSMCSDCSGQGERFSAKDRCKTCNGRKVERKKKILEVHIDKGMKDGQKITFNGEGDQEPGLE--------PGDVTIILDLKEHPVFQRKDNN--LLMKMKIRLVEALCG-FKKTISTLDNRSLLIHSPPGQVIKPNDLKCVHNEGMPVYREPFEKGLLIIRFEIEFPDDHWLPEHMLPDLERLLPVREHIMLT-------------------DDMEEVDLCQVDFE-----------------SQQRRNHSAEAYHEDDEEERRQTGVQCQTQ-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFV9-1", "uniprot_id": "Q9VFV9_DROME", "id": "Q9VFV9-1", "name": "", "aln": "MVKETGYYDILGVKPNATPDELKKAYRKLALKYHPDKNPNEGE---KFKAISQAYEVLSDADKRQVYDEGG---EAAIKKGGADSG--------------------DFRNPMDFFEKFFGAGFG----------------------------------------GSGGGRRRERRGKDVVHQMSVQLEELYNGATRKLQLQKNVICDKCEGRGGKKGSIEKCLQCRGNGVETRVQQIAPGIMQHIEQVCRKCSGTGETIQEKDRCKNCSGRKTVRERKVLEVHIEKGMRDGQKIVFTGEGDHEPESQ--------PGDIIILLDEKEHSTFAHAGQD--LMMKMPLQLVEALCG-FQRIVKTLDDRDLIVSTQPGEVIRHEMTKCIAEEGMPIFKNPMEKGTLIIQFEVIFP--EVINPSVVPTLKQCLPPAPEVDIP-------------------IDAEQTVLEDFDP------------------KQRRQQHQRMAYDEDDGGYQDGPRVQQCTSS------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53940-1", "uniprot_id": "APJ1_YEAST", "id": "P53940-1", "name": "J domain-containing protein APJ1", "aln": "MQQNTSLYDSLNVTAAASTSEIKKAYRNAALKYHPDKNNHTEESKRKFQEICQAYEILKDNRLRALYDQYGTTDEVLIQEQQAQAQRQQAGPFSSSSNFDTEAMSFPDLSPGDLFAQFFNSSATPSSNGSKSSFNFSFNNSSTPSFSFVNGSGVNNLYSSSAKYNSNDEDHHLDRGPDIKHNLKCTLKELYMGKTAKLGLNRTRICSVCDGHGGLKK--CTCKTCKGQGIQTQTRRMGP-LVQSWSQTCADCGGAGVFVKNKDICQQCQGLGFIKERKILQVTVQPGSCHNQLIVLTGEGDEVISTKGGGHEKVIPGDVVITILRLKDPNFQVINYSNLICKKCKIDFMTSLCGGVVYIEGHPSGKLIKLDIIPGEILKPGCFKTVEDMGMPKFINGVRSGFGHLYVKFDVTYPERLEPENAKKIQNILANDKYIKAERSTMETADSDCYCDLEKSYDSVEEHVLSSFEAPNLNNEVIEDDDLGDLINERDSRKRNNRRFDESNINNNNETKRNKYSSPVSGFYDHDINGY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::* ** *.*.. *: .*:*****: ********* . * **: *.***::* * * :**: * * *:: . .* *:* **.. .. : :* :: *:: *::** * * ** *::. **. *:* ** * * *:* *:: : :::.* ::* . * .* * * .. ** *: *.* :::*:::* :: * ..* * : ****. . ***: * : ... * . . : : : :*** . ..: : : .*:::: : : : *** : ..* : . . .. : :: *. : . :: * .. .. :: :.:.: . : : ", "identical_positions": 98, "similar_positions": 122, "identity": "18.46%" }, { "cls_id": "homologset.agr.SGD:S000005023", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63610-1", "uniprot_id": "TPM3_RAT", "id": "Q63610-1", "name": "Tropomyosin alpha-3 chain", "aln": "MAGSTTIEAVKRKIQVLQQQADDAEERAER---------------------------------------------------------------LQREVEGERRAREQ---------------------AEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNEM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z2H9-1", "uniprot_id": "D3Z2H9_MOUSE", "id": "D3Z2H9-1", "name": "", "aln": "MAGTTTIEAVKRKIQVLQQQADDAEERAER---------------------------------------------------------------LQQEVEGERRARKQ---------------------AEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNEM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IRU2-1", "uniprot_id": "TPM4_MOUSE", "id": "Q6IRU2-1", "name": "Tropomyosin alpha-4 chain", "aln": "MAGLNSLEAVKRKIQALQQQADDAEDRAQG---------------------------------------------------------------LQRELDGERERREK---------------------AEGDAAALNRRIQLLEEELDRAQEQLATALQNLEEAEKAADESERGMKVIENRAMKDEEKMEILEMQLKEAKHITDEADRKYEEVARKLVILEGELKRAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVSKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09495-1", "uniprot_id": "TPM4_RAT", "id": "P09495-1", "name": "Tropomyosin alpha-4 chain", "aln": "MAGLNSLEAVKRKIQALQQQADDAEDRAQG---------------------------------------------------------------LQRELDGERERREK---------------------AEGDAAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKSSDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVSKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13104-1", "uniprot_id": "TPM1_DANRE", "id": "P13104-1", "name": "Tropomyosin alpha-1 chain", "aln": "------MDAIKKKMQMLKLDKENALDRAEQAETDKKAAEERSK------------------------------------------QLEDDLVALQKKLKATEDELDKYSEALKDAQEKLELAEKKATDAEGDVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELNEGKCSELEEELKTVTNNMKSLEAQAEKYSAKEDKYEEEIKVLTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TFB7-1", "uniprot_id": "A0AB32TFB7_DANRE", "id": "A0AB32TFB7-1", "name": "", "aln": "------MDAIKKKMQMLKLDKENALDRAEQAEGDKKAAEDRSKQLEDELIQLEKRLRVTEDERDKVLEEYQSVEEKLLTAEEVATKLEDDLLALQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEGDVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMEIQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELNERCNRRLQDELRVLDQTYKSLKASEEQYSQKEDKYEEEIKVLTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYSQKLKYKAISEELDHALNDMTSM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P58771-1", "uniprot_id": "TPM1_MOUSE", "id": "P58771-1", "name": "Tropomyosin alpha-1 chain", "aln": "------MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSK------------------------------------------QLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04692-1", "uniprot_id": "TPM1_RAT", "id": "P04692-1", "name": "Tropomyosin alpha-1 chain", "aln": "------MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSK------------------------------------------QLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09493-1", "uniprot_id": "TPM1_HUMAN", "id": "P09493-1", "name": "Tropomyosin alpha-1 chain", "aln": "------MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSK------------------------------------------QLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06753-1", "uniprot_id": "TPM3_HUMAN", "id": "P06753-1", "name": "Tropomyosin alpha-3 chain", "aln": "-----MMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSK------------------------------------------QLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P21107-1", "uniprot_id": "TPM3_MOUSE", "id": "P21107-1", "name": "Tropomyosin alpha-3 chain", "aln": "-----MMEAIKKKMQMLKLDKENVLDRAEQAEAEQKQAEERSK------------------------------------------QLEDELATMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISDELDHALNDMTSI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58774-1", "uniprot_id": "TPM2_MOUSE", "id": "P58774-1", "name": "Tropomyosin beta chain", "aln": "------MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCK------------------------------------------QLEEEQQALQKKLKGTEDEVEKYSESVKDAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58775-1", "uniprot_id": "TPM2_RAT", "id": "P58775-1", "name": "Tropomyosin beta chain", "aln": "------MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCK------------------------------------------QLEEEQQALQKKLKGTEDEVEKYSESVKDAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07951-1", "uniprot_id": "TPM2_HUMAN", "id": "P07951-1", "name": "Tropomyosin beta chain", "aln": "------MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCK------------------------------------------QLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R412-1", "uniprot_id": "F1R412_DANRE", "id": "F1R412-1", "name": "", "aln": "------MEAIKKKMQMLKLDKENAIDRAEQAETEQKAAEDKCK------------------------------------------QLDDELVGLQKKLKQTEDELDKYSEALKDAQEKLELSEKKAADAEGDVAALNRRIQLVEEELDRAQERLGTALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVAECKASDLEEELKNVTNNLKSLEAQAEKYSEKEDKYEEEIKVLSDKLKEAETRAEFAERTVAKLEKSIDDLEEKLSSAKEENLGMHQVLDQTLQELNSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A2R8Q650-1", "uniprot_id": "A0A2R8Q650_DANRE", "id": "A0A2R8Q650-1", "name": "", "aln": "------MEAVKKKMMMLKLDKENALDQAEQAETDRKAAEERSK------------------------------------------QHEDELIQMQKKLKGTEDELDKYSEALKDAQEKLEISEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELAESHVKQMEEELRALDQTLKTLQASEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEEKLRDAKEENIKIHATLDQTLSELNSF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P17536-1", "uniprot_id": "TPM1_YEAST", "id": "P17536-1", "name": "Tropomyosin-1", "aln": "------MDKIREKLSNLKLEAESWQEKYEELK--------------------------------------------------------------EKNKDLEQENVEK----------------------ENQIKSLTVKNQQLEDEIEKLEAGLSDSKQ----TEQDNVEKENQIKSLTVKNHQLEEEIEKLEAELAESKQLSEDS---------------------------------------HHLQSNNDNFSKKNQQLEEDLEESDTKLKETTEKLRESDLKADQLERRVAALEEQREEWERKNEELTVKYEDAKKELDEIAASLENL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ::.*: *: : :. :: : ::: . . .: * : :*. : * :*:*::: : *. : * :*: *.*. :* : : : **::* * :* *:*:::::: : : .. . :. :: . . :. : ::* :**:*:: :*: ** *: **: :: * : . : **. .: :", "identical_positions": 33, "similar_positions": 83, "identity": "9.94%" }, { "cls_id": "homologset.agr.SGD:S000005026", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54279-1", "uniprot_id": "PMS2_MOUSE", "id": "P54279-1", "name": "Mismatch repair endonuclease PMS2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEQTEGVSTECAKAIKPIDGKSVHQICSGQVVLSLSTAVKELIENSVDAGATTIDLRLKDYGVDLIEVSDNGCGVEEENFEGLAL---KHHTSKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCHGSASVGTRLVFDHNGKITQKTPYPRPKGTTVSVQHLFYTLPVRYKEFQRNIKKEYAKMVQVLQAYCIISAGVRVSCTNQLGQGKRQPVVCTSGSSGMKENIGSVFGQKQLQSLIPFVQ-------------------LPPSDAVCEEYGLSTSR-TPQNLFYVSGFISQCTHGAGRSATDRQFFFINQRPCDPAKVSKLVNEVYHMYNRHQYPFVVLNVSVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLIGMFDSDANKLNVNQQ--PLLDVEGNLVKLHTAELEKPVPGKQDNSPSLKSTADEKRVASISRLREAFSLHPTKEIKSRGPETAELTRSFPSEKRGVLSSYPSDVISYRGLRGSQDKLVSPTDSPGDCMDREKIEKDSGLSSTSAGSEEGFSTPEVASSFSSDYNVSSPEDRPSQETINCG----DLDCRPPGTGQSLKPEDHGYQCKA-LPLARLSPTNAKRFKTEERPSNVNISQRLPGPQSTSAAEVDVAIKMNKRIVLLEFSLSSLAKRMKQLQHLKAQN-KHELSYRKFRAKICPGENQAAEDELRKEISKSMFAEMEILGQFNLGFIVTKLKED----LFLVDQHAADEKYNFEMLQQHTVLQAQRLITPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDEDAPVTERAKLISLPTSKNWTFGPQDIDELIFMLSDSPG---VMCRPSRVRQMFASRACRKSVMIGTALN-ASEMKKLITHMGEMDHPWNCPHGRPTMRHVANLDVISQN----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JW47-1", "uniprot_id": "A0A0G2JW47_RAT", "id": "A0A0G2JW47-1", "name": "Mismatch repair endonuclease PMS2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQVGSSTRRECAKAIKPIDGKSVHQICSGQVVLSLSTAVKELIENSVDAGATSIDLRLKDYGVDLIEVSDNGCGVEEENFEGLAL---KHHTSKIREFADLTQVETFGFRGEALSSLCALSDVTISTCHVSASIGTRLVLDHNGKIIQKTPCPRPKGTTVSVQNLFYTLPVRHKEFQRNIKKEYAKMVQVLQAYCIISAGIRVSCTNQLGQGKRQPVVCTSGSSGMKENIGSVFGQKQLQSLVPFVQ-------------------LPPSDSVCEEYCLSACG-TPQSPFRISGFISQCTHGAGRSSTDRQFFFINQRPCDPAKVSRLVNEVYHMYNRHQYPFVVLNVSVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLMGMFDSDANKLSVNQQ--PLLNVEGNLVKLHTAEVGE-----QENSPSLRITAEEKRVASVSRLREAYSLHRTTETKSWGPETPELKQSFPSQKRGVSSSCPSDIISYRGLCGSQDKLVSPTDSPGDCMDREKGEKDSGLSSTSAGSEEGFSTPEVASSFSSDCNVSSPEDRPSQENTNCGEQFLEVDDHLSGTGHHLKPEDNGYKCRASLPPTRLSPSNAKRFRTEDRPSNVGV------PQNTSAAEVDVAVKINKKIVLLDFSLSSLAKQMKQLQHLKQQS-KSEHNYRKFRAKICPGENQAAEDELRREIRKSMFAEMEILGQFNLGFIVTKLKED----LFLVDQHAADEKYNFEMLQQHTVLQAQRLITPQTLNLTAVNEAVLIENLEIFRKNGFDFIIDEDAPVTERAKLISLPTSKNWTFGPQDIDELIFMLSDSPG---VMCRPSRVRQMFASRACRKSVMIGTALS-ASEMKKLISHMGEMDHPWNCPHGRPTMRHIANLDVISQN----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54278-1", "uniprot_id": "PMS2_HUMAN", "id": "P54278-1", "name": "Mismatch repair endonuclease PMS2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERAESSSTEPAKAIKPIDRKSVHQICSGQVVLSLSTAVKELVENSLDAGATNIDLKLKDYGVDLIEVSDNGCGVEEENFEGLTL---KHHTSKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCHASAKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLIPFVQ-------------------LPPSDSVCEEYGLSCSD-ALHNLFYISGFISQCTHGVGRSSTDRQFFFINRRPCDPAKVCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLIGMFDSDVNKLNVSQQ--PLLDVEGNLIKMHAADLEKPMVEKQDQSPSLR-TGEEKKDVSISRLREAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDKGVLRPQKEAVSSSHGPSDPTDRAEVEKDSGHGSTSVDSE-GFSIPDTGSHCSSEYAASSPGDRGSQEHVDSQEKAPKTDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEILSSSDICQKLVNTQDMSASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQS-EGEQNYRKFRAKICPGENQAAEDELRKEISKTMFAEMEIIGQFNLGFIITKLNED----IFIVDQHATDEKYNFEMLQQHTVLQGQRLIAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDENAPVTERAKLISLPTSKNWTFGPQDVDELIFMLSDSPG---VMCRPSRVKQMFASRACRKSVMIGTALN-TSEMKKLITHMGEMDHPWNCPHGRPTMRHIANLGVISQN----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GXJ5-1", "uniprot_id": "A0AC58GXJ5_DANRE", "id": "A0AC58GXJ5-1", "name": "Mismatch repair endonuclease PMS2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEQQLSN-IESAGAIKAIDKQSVHQICSGQVVLSLATAVKELVENSIDAGATNVDVKLKDNGIELVEVSDNGKGVEEQNYEGLTL---KHHTSKLKEFSDLIHVETFGFRGEALSSLCALSDLSVVTCHESAQIGARLVYDHDGRLTQCVPHPRQHGTTVTLQKLFSTLPVRHKEFQRNIKKEYSKMIFVLQSYCIISTGVRITCSNQMGQGKRSTVLCTSGSNSMRDNIGAVFGPKQLQSLIPFRQ-------------------ISPNDSVKEDYGLGGVD-VPKDLFNIDGFVSQGDHGVGRSATDRQFFFINKRPCDPVKVSKLVNEVYHMYNRHQYPFVALNIAVASDCVDVNVTPDKRQILLQEEKLLLAILKSSLIAMFETGVNKISLNHIS-PAFTSMSRPTGTSACSDDQ---EMGSVSETLTYDGPPKTSINLAGLKEAFSNHQAPGIGSK-QSSHKAACAGPSQKK-MLSFVSCSKKVTDFVRPPLKSPTSFTAVSSIKLSTVCSVKYKSAFDSDADGS-GAASPKSAED-DPEIKQENHSESVLHHVINKTDVKAEIVDEP--MDENLWSYETLPETKSEQHQNRIFSPEAKRARREDEPPAQNCLVDFK--SRNASLKFDAPVNIKKKTVVLPFSQQELSKRMQRLQAQRTKSNEQEPKYRRFRAKINPGENQTAEDELKKEISKDMFKEMEIIGQFNLGFIITKIKSD----LFIIDQHATDEKYNFEMLQQNTVLKGQRLIVPQSLHLPAISETVLMENLEIFRKNGFDFLIDEDAQVMDRVKLVSLPTSKNWTFGPNDIEELIFMLSDSPG---IMCRPSRVRQMFASRACRKSVMVGTALN-TSEMKKLVLHMGEIEQPWNCPHGRPTMRHLANLDMISQD----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O95744-1", "uniprot_id": "PM2P2_HUMAN", "id": "O95744-1", "name": "Putative postmeiotic segregation increased 2-like protein 2", "aln": "-----------------------------------------------------------------------------------MGESSRKPPTPTPEGPTVSVKQLFS---------------------------TLPVRHKEFQRNIKKKR---ACFPFAFCRDCQFLEGS-------------------------PAMLPVQPAKLTEPAKAIKPIDRKSVHQICSGPVVLSLSTAVKKIVGNSLDAGATNIDLKLKDYGMDLIEVSGNGCGVEEENFEGLSLSALKHHTSKIREFADLTRVETFGFQGKALSSLCALSDVTISTCHVSAKVGTRLVFDHDGKIIKKTPYPHPRGTTVSVKQLFSTLPVRHKEFQRNIKKKRACFPFAFCRDCQFLE----------------------GSPAMLP--------------------------------------VQPAKLTVTG-ELRACR-SWKT---REGITEAVG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4D2B8-1", "uniprot_id": "PM2P1_HUMAN", "id": "A4D2B8-1", "name": "Putative postmeiotic segregation increased 2-like protein 1", "aln": "MVTMCGGHRPENFLHQVLTEFGEELAGEGKSEVGGGAPRSYLQVASAECWAAAPAVHVGEPVHAGGLHTERGADPVIGLYLVHRGGACQTPTVGNRQTPTLGIHARPRRRATTSLLTLLLAFGKNAVRCALIGPGSLTSRTRPLTEPLGEKERREVFFPPRPERVEHNVESSRWEPRRRGACGSRGGNFPSPRGGSGVASLERAESSSTEPAKAIKPIDRKSVHQICSGPVVPSLSTAVKELVENSLDAGATNIDLKLKDYGVDLIEVSGNGCGVEEENFEGLTL---KHHTSKIQEFADLPQVETFGFRGEALSSLCALSDVTISTCHVSAKVGTRLVFDHYGKIIQKTPYPHPRGMTVSVKQLFSTLPVHHKEFQRNIKKKRACFPFAFCRDCQFPE----------------------ASPAMLP--------------------------------------VQPAELTPRSTPPHPCS-LEDN---VITVFSSVKNGPGSSR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1ZA03-1", "uniprot_id": "A1ZA03_DROME", "id": "A1ZA03-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MLETNYNADTE-----------------------------------------------------EEPDVPPPTTALSGQIKAIGKDTVHKICSGQVVLSLAVAVKELVENSIDAGATLVEIKLKDQGLQSVEVSDNGSGVEEMNLEGMTA---KYHTSKIREFVDLLGVETFGFRGEALSSLCALSDMVIQTRHKSTDVGVKVELDHEGRIKKRSPCARGVGTTVLLANLFSTLPVRRRDFTRNIKKEFTKMCQILQAYCLVTKGVRILCSNHTPKGAKTIVLQTHGDQEVMANISAIFGARQAADLVPLKSPFGQGQLTEAELRADLESGADLADTTSPQISTEDVERLNQADFQLEGFISSCRHGAGRSSRDRQFFFVNSRPCDPKNIAKVMNEVYHRYNVQQQPFIYLNIITARSDVDVNLTPDKRQLLINNERILLLALKKSLLDTFGQTPATFQMQNT-----TIVSMLEPKTNSGKTKFPKESSKDDQHEEVSEEDVPTTSTQRFMDVLTQWRRTGDTKGTAPSVPVKRRCSESEELVTRTLKMQKIHTFLSQESPNEQSSKCEAESDAASDVDMAK-KDKTQVSLDNSFLNLKELAKESEAYDLLTKPQNTPRIDCKVLTPIKSRRSIFEFKTDAMALDKQESPAELNSQPPSFTQLSEETDIASDEDDHIELPTRIEFDEEMEEGLPSNFSSGEITTSLEEIASSLKAHE------QQQRDRRTRTKLQRLRFKTEINPNQNTSAEAELQREIDKEDFARMEIIGQFNLGFIIVKLEDD----LFIVDQHATDEKYNFETLQRTTQLEYQRLAVPQNLELTAVNEMVLLNHIDVFEKNGFKFEVDHEAPATKKVRLLGKPHSKRWEFGKEDIDELIFMLQDAPEG--TICRPSRVRAMFASRACRKSVMIGTALSRNTTMRRLITQMGEIEQPWNCPHGRPTMRHLINIAMLINSDENDEQEPPA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14242-1", "uniprot_id": "PMS1_YEAST", "id": "P14242-1", "name": "DNA mismatch repair protein PMS1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQIHQINDIDVHRITSGQVITDLTTAVKELVDNSIDANANQIEIIFKDYGLESIECSDNGDGIDPSNYEFLAL---KHYTSKIAKFQDVAKVQTLGFRGEALSSLCGIAKLSVITTTSPPKA-DKLEYDMVGHITSKTTTSRNKGTTVLVSQLFHNLPVRQKEFSKTFKRQFTKCLTVIQGYAIINAAIKFSVWNITPKGKKNLILSTMRNSSMRKNISSVFGAGGMRGLEEVDLVLDLN---------------PFKNRMLGKYTDDPDFLDLDYKIRVKGYISQNSFGCGRNSKDRQFIYVNKRPVEYSTLLKCCNEVYKTFNNVQFPAVFLNLELPMSLIDVNVTPDKRVILLHNERAVIDIFKTTLSDYYNRQELALPKRMCSQSEQQAQKRLKTEVFDDRSTTHESDNENYHTARSESNQSNHAHFNSTTGVIDKSNGTELTSVMDGNYTNVTDVIGSECEVSVDSSVVLDEGNSSTPTKKLPSIKTDSQNLSDLNLNNFSNPEFQNITSPDKARSLEKVVEEPVYFDIDGEKFQEKAVLSQADGLVFVDNECHEHTNDCCHQERRGSTDTEQDDEADSIYAEIEPVEINVRTPLKNSRKSISKDNYRSLSDGLTHRKFEDEILEYNLSTKNFKEISKNGKQMSSIISKRKSEAQENIIKNKDELEDFEQGEKYLTLTVSKNDFKKMEVVGQFNLGFIIVTRKVDNKYDLFIVDQHASDEKYNFETLQAVTVFKSQKLIIPQPVELSVIDELVVLDNLPVFEKNGFKLKIDEEEEFGSRVKLLSLPTSKQTLFDLGDFNELIHLIKEDGGLRRDNIRCSKIRSMFAMRACRSSIMIGKPLN-KKTMTRVVHNLSELDKPWNCPHGRPTMRHLMELRDWSSFSKDYEI----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: *. **:* ** *: .*:.***::: **:**.*. ::: :** *:: :* *.** *:: * * :: *::***: :* *: *:*:**:*:******.::.: : * ... :: * *:: . . .: * ** : :** .***: ::* :.:*:: : : . . . : . . . ", "identical_positions": 57, "similar_positions": 71, "identity": "5.14%" }, { "cls_id": "homologset.agr.SGD:S000005027", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6GQS1-1", "uniprot_id": "SCMC3_MOUSE", "id": "Q6GQS1-1", "name": "Mitochondrial adenyl nucleotide antiporter SLC25A23", "aln": "---------------------------------------------------------------------------------------------------MRGGSSDAERRQR----WGRLFEELDSNKDGRVDVHELRQGLARLGRGDPD--RAQQGVSSDWDADPDGGLSLEEFTRYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRAL----------------------------------------GISISLEQAEKILHSMDRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSQEEKLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKSNRLNILG---------------------GLRNMIQEGGVLSLWRGNGINVLKIAPESAIKFMAYEQIKRAIRGQQE-----TLHVQERFVAGSLAGATAQTIIYPMEVLKTRLTLRRTG-QYKG---LLDCAKRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNRWLQQYSHESANPGILVLLG-CGTISSTCGQIASYPLALVRTRMQAQASIEGG-----------------PQVSMVGLLRHILSQEGVWGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JVD2-1", "uniprot_id": "A0A0G2JVD2_RAT", "id": "A0A0G2JVD2-1", "name": "Mitochondrial adenyl nucleotide antiporter SLC25A23", "aln": "---------------------------------------------------------------------------------------------------MRGGSGDAERRQR----WGRLFEELDSNKDGRVDVHELRQGLARLGRGDPD--RAQQGISSDWDSDADGGLSLEEFTQYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRAL----------------------------------------GFSISMEQAEKILHSMDRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSKQEKLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKSNRLNILG---------------------GLRNMVQEGGLLSLWRGNGINVLKIAPESAIKFMAYEQIKRAICGQQE-----TLHVQERFVAGSLAGATAQTIIYPMEVLKTRLTLRRTG-QYKG---LLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNRWLQQYSHESANPGILVLLA-CGTISSTCGQIASYPLALVRTRMQAQASIEGG-----------------PQVSMVGLLRHILSQEGVWGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BV35-1", "uniprot_id": "SCMC3_HUMAN", "id": "Q9BV35-1", "name": "Mitochondrial adenyl nucleotide antiporter SLC25A23", "aln": "---------------------------------------------------------------------------------------------------MRGSPGDAERRQR----WGRLFEELDSNKDGRVDVHELRQGLARLGGGNPDP-GAQQGISSEGDADPDGGLDLEEFSRYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRAL----------------------------------------GISISLEQAEKILHSMDRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSKQEKLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILG---------------------GLRSMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQE-----TLHVQERFVAGSLAGATAQTIIYPMEVLKTRLTLRRTG-QYKG---LLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLLA-CGTISSTCGQIASYPLALVRTRMQAQASIEGG-----------------PQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TVL2-1", "uniprot_id": "A0AB32TVL2_DANRE", "id": "A0AB32TVL2-1", "name": "", "aln": "-----------------------------------------------------------------------------------------MWPRGWTQARCQDSGVDQDREQL----WAELFQQLDLNKDGRVDVNELRIGLAARGLSWSS---VEEQIVRAGDINHDGQLDFEEFTEYLRSHEKRLRLMFRSLDRNNDGEVDVGEIQQSLHNL----------------------------------------GVDITLEQAAKILQSMDKDHSMTIDWIEWRDHFLFNPLHNMEEIAQFWKHSVMLDIGEHLTVPDEFSEKEKRSGFVWRQLMAGAVAGSVSRTGTAPLDRLKVFLQVHGQSSDKGNVWS---------------------GLRAMVKEGGLTALWRGNGINVLKIAPETAIKFLAYEQIKRLMRGSNEG---GTLKVHERFVAGSLAGATAQTIIYPMEVLKTRLTLRKTG-QYSS---VADCAKQILQKEGVRAFYKGYLPNMLGIIPYAGIDLAVYETLKNAWLQRHTEGSADPGVLVLVG-CGTVSSTCGQLASYPLALIRTRMQAQASIKGA-----------------PQLSMLTLFRSIVAQEGVVGLYRGIAPNFLKVIPAVSISYVVYEHMRALIFRFTGYVPVDAVK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BMD8-1", "uniprot_id": "SCMC1_MOUSE", "id": "Q8BMD8-1", "name": "Mitochondrial adenyl nucleotide antiporter SLC25A24", "aln": "-----------------------------------------------------------------------------------------MLRWLRAFVLPTAACHDAEPPTR----YETLFRALDRNGDGVVDIGELQQGLQSLGIPLGQ--DAEEKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEPSEIVQSLQML----------------------------------------GLHISEKQAELILQSIDSDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGVAGAVSRTSTAPLDRLKVMMQVHGSKS--MNIFG---------------------GFRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQ-----KLGTFERFISGSMAGATAQTFIYPMEVLKTRLAVAKTG-QYSG---IYGCAKKILKHEGFGAFYKGYIPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLS-CGALSSTCGQLASYPLALVRTRMQAQATVEGA-----------------PQLSMVGLFQRIVSKEGVSGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVAQK--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7EXY7-1", "uniprot_id": "F7EXY7_RAT", "id": "F7EXY7-1", "name": "Mitochondrial adenyl nucleotide antiporter SLC25A24", "aln": "-----------------------------------------------------------------------------------------MLRWLRAFVLPTAVCQDAEPPTR----YETLFRALDRNGDGVVDIGELQQGLQSLGIPLGQ--AAEEKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEPFEIVQSLQML----------------------------------------GLNISEKQAELILQSIDSDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGVAGAVSRTSTAPLDRLKVMMQVHGSKS--MNIFG---------------------GFRQMVKEGGIRSLWRGNGINVIKIAPETAVKFWAYEQYKKLLTEEGQ-----KLGTSERFISGSMAGATAQTFIYPMEVLKTRLAVAKTG-QYSG---IYGCAKKILKHEGFRAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVVVLLG-CGALSSTCGQLASYPLALVRTRMQAQATTEGA-----------------PQLSMVGLFQRIVSKEGVSGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVAQK--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NUK1-1", "uniprot_id": "SCMC1_HUMAN", "id": "Q6NUK1-1", "name": "Mitochondrial adenyl nucleotide antiporter SLC25A24", "aln": "-----------------------------------------------------------------------------------------MLRWLRDFVLPTAACQDAEQPTR----YETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQ--DAEEKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTL----------------------------------------GLTISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFG---------------------GFRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQ-----KIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTG-QYSG---IYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLG-CGALSSTCGQLASYPLALVRTRMQAQAMLEGS-----------------PQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B1AUS6-1", "uniprot_id": "B1AUS6_MOUSE", "id": "B1AUS6-1", "name": "Mitochondrial adenyl nucleotide antiporter SLC25A24", "aln": "-----------------------------------------------------------------------------------------MLRRLQDFLLPSEACQNDYNRLA----YEVLFEDLDHNGDGVVDITELRDGLKHWNSSFSE--DTEKEIFMDADSNADSGLDFEEFVQYLQDHEKKMKLAFKSLDKNDDGVIDASEIVAAVRSL----------------------------------------GIHISLSQAKDILKSMDFDGSMTVDWDEWRDFFFFHPAKNITDIVRFWKHSTIIDIGESISIPDEFTEQEKMSGEWWKRLVAAGIASAITRTCTAPLERLKVTMQVQSLKVNKMGLVH---------------------MFKQMVKEGGFFSLWRGNGVNILKIAPETAIKIGAYEQYKKLLSFDGD-----HLGVLQRFTAGCMAGATSQTCVYPMEVIKTRLNLSKTG-EYSG---LVDCVRKLLKREGIQAFSKGYVPNLLSIIPYAGLDLTIFELLKNHWLEHYAGNSVNPGIAIVLG-CSTVSHTCGQLASFPLILVRTRMQAVMLEK-------------------ETVRMMQLIQEIYTKEGKKGFFRGFTPNVLKLLPAVGIGSVAHELVKRLFGLI----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZTW5-1", "uniprot_id": "D3ZTW5_RAT", "id": "D3ZTW5-1", "name": "Mitochondrial adenyl nucleotide antiporter SLC25A24", "aln": "-----------------------------------------------------------------------------------------MLSWLQDVLWPSKAPKSDYDDLA----FEILFEDLDRNGDGVVDITELRDGLEHWNSSFGI--DPEKKILKSADSNADSGLDFGEFVKYLQDHEKKMKLAFKSLDKNADGVIDASEVVAAMKSL----------------------------------------GIHISLAQANDILKSMDADGSMTVDWDEWRDYFFFHPAKNVTDIIRFWKHSTIIDIGESVSIPDEFTEQEKKSGEWWKRLVAAGIASAITRTCTAPLDRLKVMIQVQSSKMSKLRLVH---------------------VFKQMVKEGGLFSLWRGNGVNIFKITPETAIKIGAYEQYKKLLSFEDA-----NLGFLQRFTAGSMAGITSQTCVYPLEVIKTRLILGRTG-EFSG---IIDCGRKLLRREGIQAFSRGYVPNLLSIVPYAGLDLTIFELLKNYWLEHYAESSVNPGLAIVLG-CSTLSHTFGQLASFPLNLVRTRMQAAMLEN-------------------ETIPMMQLIQEIYTKEGKKGFFRGLTPNVLKLLPAVGIGCVAHELVNLLFGLT----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q66L49-1", "uniprot_id": "SCMC1_DANRE", "id": "Q66L49-1", "name": "Mitochondrial adenyl nucleotide antiporter SLC25A24", "aln": "-----------------------------------------------------------------------------------------MHQLIRKFVFTESHCLEEEDNTKS---FAELFEKLDVNKDGKVDVSELKTGLAAMGFSMGK--GEAQKIVTSGDTDKDEGLDFEEFSKYLKEHEKKLRLTFKSLDKNEDGRVDAKEIQQSLKDL----------------------------------------GINLSDKDAEKILHSIDVDGTMTLDWNEWREHFLFNPAEDLQQIIRYWKKSTVLDIGDSLTIPDEFTEEEKTTGMWWKQLAAGGVAGAVSRTGTAPLDRMKVFMQVHSSKTNKISLVN---------------------GFKQMIKEGGVASLWRGNGVNVIKIAPETAIKFMAYEQYKKLLSKDGG-----KVQSHERFMAGSLAGATAQTAIYPMEVMKTRLTLRKTG-QYSG---MFDCAKKILRKEGVKAFYKGYVPNILGIIPYAGIDLAVYETLKNTWLSHYAKDTANPGVLVLLG-CGTISSTCGQLASYPLALIRTRMQAMASMEGS-----------------EQVSMSKLVKKIMQKEGFFGLYRGILPNFMKVIPAVSISYVVYEYMRSGLGISK---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2ASZ8-1", "uniprot_id": "SCMC2_MOUSE", "id": "A2ASZ8-1", "name": "Mitochondrial adenyl nucleotide antiporter SLC25A25", "aln": "-----------------------------------------------------------------------------------------MLCLCLYVPIAGAAQTEFQYFES-----KGLPAELKS-------IFKLSVFIPSQEFSTYR--QWKQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDL----------------------------------------GVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMCIVG---------------------GFTQMIREGGAKSLWRGNGINVLKIAPESAIKFMAYEQMKRLVGSDQE-----TLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTG-QYSG---MLDCARRILAKEGVAAFYKGYIPNMLGIIPYAGIDLAVYETLKNTWLQRYAVNSADPGVFVLLA-CGTISSTCGQLASYPLALVRTRMQAQASIEGA-----------------PEVTMSSLFKQILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K3P6-1", "uniprot_id": "SCMC2_RAT", "id": "Q8K3P6-1", "name": "Mitochondrial adenyl nucleotide antiporter SLC25A25", "aln": "-----------------------------------------------------------------------------------------MLCLCLYVPIAGEAQTEFQYFES-----KGLPTELKS-------IFKLSVFIPSQEFSTYR--QWKQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDL----------------------------------------GVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMCIIG---------------------GFTQMIREGGAKSLWRGNGINVLKIAPESAIKFMAYEQMKRLVGSDQE-----TLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTG-QYSG---MLDCAKRILAKEGVAAFYKGYIPNMLGIIPYAGIDLAVYETLKNTWLQRYAVNSADPGVFVLLA-CGTISSTCGQLASYPLALVRTRMQAQASIEGA-----------------PEVTMSSLFKQILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6KCM7-1", "uniprot_id": "SCMC2_HUMAN", "id": "Q6KCM7-1", "name": "Mitochondrial adenyl nucleotide antiporter SLC25A25", "aln": "-----------------------------------------------------------------------------------------MLCLCLYVPVIGEAQTEFQYFES-----KGLPAELKS-------IFKLSVFIPSQEFSTYR--QWKQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDL----------------------------------------GVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVG---------------------GFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQE-----TLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTG-QYSG---MLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLA-CGTMSSTCGQLASYPLALVRTRMQAQASIEGA-----------------PEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2CEQ0-1", "uniprot_id": "SCM2B_DANRE", "id": "A2CEQ0-1", "name": "Mitochondrial adenyl nucleotide antiporter SLC25A25-B", "aln": "-----------------------------------------------------------------------------------------MLCLCLYVPVHISERTEFEYFES-----ESLPVQLKS-------LFKLSLFLPSQEFDSYR--KWRKKVVKAGDKDLDGQLDFEEFVHYLRDHEKKLRLVFKSLDKKNDGHIDSQEIMQSLRDL----------------------------------------GVHISEEQAEKILKSMDKNGTMTIDWNEWRDYHLLHPAENIPEIILYWKHSTIFDVGESMLVPDEFTAEEKNTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHATRSNSMGIAG---------------------GFTQMIREGGLRSLWRGNGINVLKIAPESAIKFMAYEQIKRLIGSNQE-----TLGILERLVSGSLAGAIAQSSIYPMEVLKTRLALGRTG-QYSG---IADCAKHIFKKEGMTAFYKGYIPNMLGIIPYAGIDLAVYETLKNSWLQRFATDSADPGVFVLLA-CGTMSSTCGQLASYPLALVRTRMQAQASQEGS-----------------PQMTMSGLFRHIVRTEGAIGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6NYZ6-1", "uniprot_id": "SCM2A_DANRE", "id": "Q6NYZ6-1", "name": "Mitochondrial adenyl nucleotide antiporter SLC25A25-A", "aln": "-----------------------------------------------------------------------------------------MLCLCLYVPVHNSDQIEVEYFES-----NGLPSELKS-------LKSLSVLLPSQEFSTYR--RWRKKSLKTEEKEHDGQLDFEEFVHYLQDHEKDLKLVFKSMDRKIAGQVNANDIVNSLRDL----------------------------------------GVHISLKQAEKVLKSMDKNGTMTIDWNEWKKYPTLQPAENIPEIILYWKHSTIFDVGESLMVPDEFTVEEHLTGMWWRHLVSGGGAGAVSRTCTAPLDRLKVLMQVHGCQGKSMCLMS---------------------GLTQMIKEGGVRSLWRGNGINVIKIAPETALKFMAYEQIKRVMGSSQE-----TLGISERFVAGSLAGVIAQSTIYPMEVLKTRLALRKTG-QYKG---ISDCAKHILKTEGMSAFYKGYVPNMLGIIPYAGIDLAVYETLKNTWLQRYGTENADPGVFVLLA-CGTVSSTCGQLASYPLALIRTRMQAQASVEGS-----------------SQVSMTGLFKQIMKTEGPTGLYRGLTPNFLKVIPAVSISYVVYEHIKSTLGVRSR--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BVN7-1", "uniprot_id": "S2541_MOUSE", "id": "Q8BVN7-1", "name": "Calcium-independent mitochondrial carrier protein SCaMC-3L", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGVH-----------------------------------------------------------------------------------------------------------LEVLDTGEQLMVPVDVLEEENK-GTLWKFLLSGAMAGAVSRTGTAPLDRARVYMQVYSSKSNFRNLLS---------------------GLRSLVQEGGVRSLWRGNGINVLKIAPEYAIKFSVCEQSKNFFYGVHS-----SQLFQERVVAGSLAVAVSQTLINPMEVLKTRLTLRFTG-QYKG---LLDCARQILERDGTRALYRGYLPNMLGIIPYACTDLAVYELLQCLWQK-LGRDMKDPSGLVSLS-SVTLSTTCGQMASYPLTLVRTRMQAQDTVEG------------------SNPTMQGVFKRILSQQGWPGLYRGMTPTLLKVLPAGGISYLVYEAMKKTLGVQVLSR------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B8ZHC9-1", "uniprot_id": "S2541_RAT", "id": "B8ZHC9-1", "name": "Calcium-independent mitochondrial carrier protein SCaMC-3L", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGVH-----------------------------------------------------------------------------------------------------------LEVLDTGEQLMVPGDVLEEENK-GTLWKFLLSGAMAGAVSRTGTAPLDRARVYMQVYSSKSNFRHLLS---------------------GLRSLVQEGGIRSLWRGNGINVLKIAPEYAIKFSVFEQSRNFFYGVHT-----SPSFQERVVAGSLAVAISQTLINPMEVLKTRLTLRFTG-QYKG---LLDCARQILERDGTRALYRGYLPNMLGIIPYACTDLAVYELLRCLWQK-SGRDMKDPSGLVSLS-SVTLSTTCGQMASYPLTLVRTRMQAQDTVEG------------------SNPTMLGVFKRILNQQGWPGLYRGMTPTLLKVLPAGGISYLVYEAMKKTLGVQVLSR------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N5S1-1", "uniprot_id": "S2541_HUMAN", "id": "Q8N5S1-1", "name": "Mitochondrial carrier protein SCaMC-3L", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGAQPGEPQNTCSRIQTLFRR-----------------------------------------VKTLLIKAPPPPQPPPPPPSWNPGCTHVYGYAFGHMHD---NNLEHLPSQQVLDTGEQLMVPVEVLEVDNK-EALWKFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNFTNLLG---------------------GLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQG-----SPPFQERLLAGSLAVAISQTLINPMEVLKTRLTLRRTG-QYKG---LLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEMLQCFWVK-SGRDMGDPSGLVSLS-SVTLSTTCGQMASYPLTLVRTRMQAQDTVEG------------------SNPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKKTLGI-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0E8F2-1", "uniprot_id": "SCMC_DROME", "id": "Q0E8F2-1", "name": "Mitochondrial adenyl nucleotide antiporter SCaMC", "aln": "MVRKQVGIENSASLAVSKQQDQKEQDYKPEDQKQQHIDIDLTPDPASNFNFAQQAQANYSARTLAASYEHGQNLGLQHAHLATSSTTNTPLAYDLHEVASSGSILPTEIPIEDEERLERIFNKLDRDGDGRIDIHDLSAALHEFGLSSVY----AEKFLQQSDKDQSGNVGFAEFLHYVREHEKNLVLQFSHLDKNRDGKVDLEELISAFKDL----------------------------------------GLDIDMDEARNLLTRMDKDGSLNISFNEWRDFMLLAPSTDIHDLIKFWRHSTYLDIGEDMNVPDDFTQKEMQTGLWWRHLVAGGIAGAVSRTCTAPLDRIKVYLQVQ---TQRMGISE---------------------CMHIMLNEGGSRSMWRGNGINVLKIAPETAFKFAAYEQMKRLIRGDDGS---RQMSIVERFYAGAAAGGISQTIIYPMEVLKTRLALRRTG-QYAG---IADAAVKIYKQEGVRSFYRGYVPNILGILPYAGIDLAVYETLKRRYIANHDNNE-QPSFLVLLA-CGSTSSTLGQLCSYPLALVRTRLQAQAAETIANQKRKTQIPLKSSDAHSGEETMTGLFRKIVRQEGLTGLYRGITPNFLKVLPAVSISYVVYEYTSRALGIKMS--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D6W196-1", "uniprot_id": "CMC1_YEAST", "id": "D6W196-1", "name": "Truncated non-functional calcium-binding mitochondrial carrier SAL1-1", "aln": "-------------------------------------------------------------------------------------------------MLLKNCETDKQRDIR----YACLFKELDVKGNGQVTLDNLISAFEKNDHPLKGNDEAIKMLFTAMDVNKDSVVDLSDFKKYASNAESQIWNGFQRIDLDHDGKIGINEINRYLSDLDNQSICNNELNHELSNEKVNKFSRFFEWAFPKRKANIALRGQASHKKNTDNDRSKKTTDSDLYVTYDQWRDFLLLVPRKQGSRLHTAYSYFYLFNEDVDLSSEGDVTLINDFIRGFG-FFIAGGISGVISRTCTAPFDRLKVFLIARTDLSSILLNSKTDLLAKNPNADINKISSPLAKAVKSLYRQGGIKAFYVGNGLNVIKVFPESSIKFGSFEVTKKIMTKLEGCRDTKDLSKFSTYIAGGLAGMAAQFSVYPIDTLKFRVQCAPLDTKLKGNNLLFQTAKDMFREGGGQIILQRCHSRYSGHISLCCIRFGDFFCLKKMVYCQTGKDPEPTTRSGHSKQPGCTSNGCIQWNCRSFCCLSNQ-----------------------------------------------SFKNKTTSPRNICTSLCV-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . :: . : :. : : :.. :. ::** ***::* :: : . . : :** ::: *** *::*: ** :.*: * :. . . :* * :* : *::.:* *: . : . : : * : : .. . :. . : : *: . * * . .: : .: ::. .. :: .: : ", "identical_positions": 27, "similar_positions": 81, "identity": "4.04%" }, { "cls_id": "homologset.agr.SGD:S000005028", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P42566-1", "uniprot_id": "EPS15_HUMAN", "id": "P42566-1", "name": "Epidermal growth factor receptor substrate 15", "aln": "-------MAAAAQLSLTQLSSGNPVYEKYYRQVDTGNTGRVL-----------------ASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALRLVACAQNGLEVSLSS--------------------------------------------------LNLAVPPPRFHDTSSPLLISGTSAAELP------------------------------------------------------------------WAVKPEDKAKYDAIFDSLSPVN-GFLSGDKVKPVLLNSKLPVDILGRVWELSDIDHDGMLDRDEFAVAMFLVYCALEKEPVPMSLPPALVPPSKRK--------------------------------------------------------TWVVSPAEKAKYDEIFLKTDK------------------DMDGFVSGLEVREIFLKTGLPSTLLAHIWSLCDTKDCGKLSKDQFALAFHLISQKLIKGIDPPH--VLTPEMIPPSDRASLQKNIIGSSPVADFSAIKELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELS-------------------------------RLQQETAELEESVESGKAQLEPLQQHLQD------------------------------------------------------------SQQEISSMQMKLMEMKDLENHN--------------SQLNWCSSPHSILVNGATDYCSLSTSSSETANLNEHVEGQS------NLESEPIHQESPARSSPELLPSGVTDENEVTT----------------------------------AVTEKVCSELDNNRHS--------------------------------------------------------------------------------KEEDPFNVDSSSLTGPVADTNLDFFQSDPFVGSDPFKDDPFGKIDPFGGDPFK-----GSDPF-----------ASDCFFRQST--DPFATSSTDPFSAA-------------NNSSITSVETLKHNDPFAPGGTVVAASDSATDPFASV--FGNESFG-------------------------GGFADFSTLSKVNNEDPFRSATSSSVSNVVITKNVFEETSVKSEDEP------PALPPKIGTPT----RPCPL----------PPGKRSINKLDSPDPFKLNDPFQPFPGNDSPKEKDPEIFCDPFTSATTTTNKEADPSNFANFSAYPSEEDMIEWAKRESEREEEQRLARLNQQEQEDLELAIALSKSEISEA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UBC2-1", "uniprot_id": "EP15R_HUMAN", "id": "Q9UBC2-1", "name": "Epidermal growth factor receptor substrate 15-like 1", "aln": "-------MAAPLIPLSQQIPTGNSLYESYYKQVDPAYTGRVG-----------------ASEAALFLKKSGLSDIILGKIWDLADPEGKGFLDKQGFYVALRLVACAQSGHEVTLSN--------------------------------------------------LNLSMPPPKFHDTSSPLMVT-PPSAEAH------------------------------------------------------------------WAVRVEEKAKFDGIFESLLPIN-GLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHLDRDEFAVAMHLVYRALEKEPVPSALPPSLIPPSKRKKTVFPGAVPVLPA----SPPPKDSLRSTPSHGSVSSLNSTGSLSPKHSLKQTQPTVNWVVPVADKMRFDEIFLKTDL------------------DLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQTGKLSKDQFALAMYFIQQKVSKGIDPPQ--VLSPDMVPPSERGTPGPDSSGSLGSGEFTGVKELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSELN-------------------------------RLQQEETQLEQSIQAGRVQLETIIKSLKS------------------------------------------------------------TQDEINQARSKLSQLHESR-----------------QEAHRSLEQYDQVLDGAHG-----ASLTDLANLSEGVS-------------------LAERGS-----FGAMDDP----------------------------------------FKNKALLFSNNTQE--------------------------------------------------------------------------------LHPDPFQTEDPFKSDPFKG--ADPFKGDPFQ-NDPFAEQQTTSTDPFGGDPFK-----ESDPFRGS--------ATDDFFKKQTKNDPFTS---DPFTK--------------NPSLPSKLDPFESSDPFSSS----SVSSKGSDPFGTLDPFGSGSFNSA-----------------------EGFADFSQMSKPPPSGPFTSSLGGAG---------FSDDPFKSKQDT------PALPPKKPAPP----RPKPP----------SGKSTPVSQLGSADFPEAPDPFQPLGADSGDPFQSKKGFGDPFSGKDPFVPSSAAKPSKASASGFADFTSVS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BIP7-1", "uniprot_id": "A0A8M2BIP7_DANRE", "id": "A0A8M2BIP7-1", "name": "Intersectin-1", "aln": "-MAQFPTPFGGGSDTWVISVDERAKHDQQFHSLTPTPAGFIT-----------------GDQARNFFLQSGLPAPILAQIWALADMNNDGKMDMHEFSIAMKLIKLKLQGHPLPPSLPPSMKQQPISIPPPTP-FGIPSMGAMP---GLPAVPPMPLPPL----PPGVPGMGVSPPLGASVTPP-VPSLANGAPAMIQPLSGFSHPGAVLNKTPSFNRS------SIKLQKGQ------SVEAPSAPAAPP-------PADWAVSQSSRLKYRQLFNSHDKMMSGYLTGPQARTILMQSSLPQAQLATIWNLSDIDQDGKLTAEEFILAMHLIDMAMSGLPLPPLLPPDLIPPTFRRMRSGSGVSVTSMH------STDLRSQEEPE-EEEKEAEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQER-----------LAALEKEEQERKERERLEQERRRQQELDKQLERQRELERQREEERRKEIERREAAKRELERQRQLEWERTRRQELLTQRNREQENIVLLKARKKTLEFELEALNDKKSQLEGKLQDIRSRLSIQRHEIETTNKTRELRIAEITSLQQQLQESQQWLSRLIPDKQCLNDQLKQVQQNSLHRDS-LNSLQRAIEMKESTKQQLKEQLDAVEKETRSKLLEIDAFNTQLK---------------------------ELREIHNKQQRQKQKELEAD-ITQPSHDRKSIDSQDSRLSG--TDDGVSPAWRDDGLG---KAPTPPVSQ------AWMSRVS-----EEENHSRAEIQDNLSKLFTQHPQAGKIQAQSPWSMADK---IPVSGFNQEKVKVVYYRAMYPFEARSHDEITIHPGDIVMVKGEWVDESQTGEPGWLGGEIKGKTGWFPANYAEKIPESEVPLSLRASAASSSAPKLGSHMSSASSSTTATPILPVSTEPASIAPPSSAPPPTGPASSSSSASSNWADFSTTWPSNSAVEKQDSDGWDAWPTQPTQPSLSVPSGGQIRQRSAFTPATLSGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQRGWFPK-----SYVKLISGPVRKSMSIESGSSDSPPSVKRPSPSLNKPTELGEGQNSNSNSMYPSKEYVAMYTYESNEQGDLTFQQGDVITVTKKEGDWWTGTVSGKIGVFPSNYVKPKE-SEGLGSAGKTGSLGKKPEIAQVIAPYTATGAEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLSPS--TSKTTPTDPNPPKLPTPNAVCQVIGMYDYTAQNDDELPFGKGQIINVLSREDPDWWKGELNGSVGLFPSNYVKLTTDTDPSQQWCADLHLLDMLTPVERKRQGYIHELIVTEENYVNDLQLVTETFQKPLLESDLLTEKEVAMIFVNWKELTMCNIKLLKALRVRKKMSGERMPVKMIGDILTAQLPHMQPYIRFCSCQLNGATLIQQKTDEVPEFKDFVKRLAMDPRCKGMPLSSFLLKPMQRVTRYPLIIKNILENTPESHPDHSHLRLALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQIIKPLGSSG-TDKVFSAKSHLQYRMYKTPIFLNEVLVKLPTDPSGDEPIFHISHIDRVYTIRAESINERTAWVQKIKAASELFIETEKRKREKAYLVRSQRATGIGRLMVNIVEGIELKPCRSNGKSNPYCEVTMGSQCHVTKTLQDTLNPKWNSNCQFFIKDLEQDVLCVTVFERDQFSPDDFLGRTEIRLADIKKDQGSKGPITKRLLLHEVPTGEIVVRLDLQLFDEP---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9WVE9-3", "uniprot_id": "ITSN1_RAT", "id": "Q9WVE9-3", "name": "Intersectin-1", "aln": "-MAQFPTPFGGSLDIWAITVEERAKHDQQFQSLKP-ISGFIT-----------------GDQARNFFFQSGLPQPVLAQIWALADMNKDGRMDQVEFSIAMKLIKLKLQGYQLPPALPPVMKQQPAAISSAPA-FGIGGMAGMP---PLTAVAPVPMG--------SIPVVGMSPPLVSSVPQAAVPPLANGAPPVIQPLPAFAHPAATLPKSSSFSRSGPGSQLNTKLQKAQ------SFDVASAPAA----------AEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGMSVISSS------SADQRLPEEPSSEDEQQVEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQER-----------LAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLTQRNKDQEGIVVLKARRKTLEFELEALNDKKHQLEGKLQDIRCRLATQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILSDQLKQVQQNSLHRDS-LLTLKRALEAKELARQQLREQLDEVEKETRSKLQEIDVFNNQLK---------------------------ELREIHSKQQLQKQRSIEAERLKQKEQERKSLELEKQKEEGQRRVQERDKQWQEHVQQEEQQRPRKPHEE------DKLKREDSVKKKEAEERAKPEVQDKQSRLFHPHQEPAKP-AQAPWPTTEK---GPLTISAQESAKVVYYRALYPFESRSHDEITIQPGDIVMVD-----ESQTGEPGWLGGELKGKTGWFPANYAEKIPENEIPTPAKPVTDLTSAP---------------APKLALRETPAPLPVTSSEP---------STTPNNWADFSSTWPS-STNEKPETDNWDTWAAQP---SLTVPSAGQLRQRSAFTPATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKSDVITVLEQQDMWWFGEVQGQKGWFPK-----SYVKLISGPVRKSTSIDTGPTEAPSSLKRVASPAAKPAIPGE-------------EFVAMYTYESSEHGDLTFQQGDVIVVTKKDGDWWTGTVGETSGVFPSNYVRLKD-SEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLSPG--TSKITPT--ELPKTAVQPAVCQVIGMYDYTAQNDDELAFSKGQIINVLSKEDPDWWKGEVSGQVGLFPSNYVKLTTDMDPSQQWCSDLHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLTESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILSAQLPHMQPYIRFCSCQLNGAALIQQKTDEAPDFKEFVKRLAMDPRCKGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQITKPLGSSS-TDKVFSPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDEPIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNVVEGIELKPCRSHGKSNPYCEVTMGSQCHITKTIQDTLNPKWNSNCQFFIRDLEQEVLCITVFERDQFSPDDFLGRTEIRVADIKKDQGSKGPVTKCLLLHEVPTGEIVVRLDLQLFDEP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AMD2-1", "uniprot_id": "A0A8I6AMD2_RAT", "id": "A0A8I6AMD2-1", "name": "", "aln": "MMAQFPTAMNGGPNMWAITSEERTKHDKQFDNLKP-SGGYIT-----------------GDQARTFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFSPLISARFGMGSMPNLSIHQPLPPVAPITAPLSSATSGTSIPPLMMPAPLVPSVSTS---SLPNGTASLIQPLS-IPYSSSTLPHASSYSLMMGGFG-GASIQKAQSLIDLGSSSSTSSTASLSGNSPKTGTSEWAVPQPSRLKYRQKFNSLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADIDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELVPPSFR-----GGKQIDSIN------GTLPSYQKTQE----EEPQKKLPVTFEDKRKANYERGNMELEKRRQVLMEQQQREAER-----------KAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKEIERREAAKQELERQRRLEWERIRRQELLNQKNREQEEIVRLNSKKKSLHLELEAVNGKHQQISGRLQDVRIRKQTQKTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQLSNTPDSG-ISLLHKKSSEKEELCQRLKEQLDALEKETASKLSEMDSFNNQLK---------------------------ELRESYNTQQLALEQLHKIKRDKLKELERKRLEQIQK------------KKLEDEAAR------KAKQGK------ENLWKES----------IRKEEEEKQKRLQEEKSQDRTQ-------EEER---KTEAKQSETARALVNYRALYPFEARNHDEMSFNSGDIIQVD-----EKTVGEPGWLYGSFQGKFGWFPCNYVEKMLSSDKTP---------------------------SPKKALLPPAVSLSATSAAP---------QPLCSNQPAPVTDYQNVSFSNLNVNTTWQ--------------------QKSAFTRTVSPGS-VSPIHGQGQAVENLKAQALCSWTAKKENHLNFSKHDVITVLEQQENWWFGEVHGGRGWFPK-----SYVKIIPG-----SEVKRGEPEALYAAVN-KKPTSTAYPVGE-------------EYIALYSYSSVEPGDLTFTEGEELLVTQKDGEWWTGSIGERTGIFPSNYVRPKD-QENVGNASKSGASNKKPEIAQVTSAYAASGAEQLSLAPGQLILILKKNSSGWWQGELQARGKKRQKGWFPASHVKLLGPS--AERTTPA---------FHAVCQVIAMYDYIANNEDELNFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYVKMTTDSDPSQQWCADLQALDTMQPMERKRQGYIHELIETEERYMDDLQLVIEVFQKRMAESGFLTEAEMALIFVNWKELIMSNTKLLKALRVRKKTGGEKMPVEMMGDILAAELSHMQAYIRFCSCQLNGAALLQQKTDEDADFKEFLKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPQNHVDHSSLKLALERAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLAEQLIFNSLTNCLGPRKLLYSGKLYKTKSNKELHGFLFNDFLLLTYLVRQFAASSGFEKLFSSKSSAQFKMYKTPIFLNEVLVKLPTDPSSDEPVFHISHIDRVYTLRTDNINERTAWVQKIKAASEQYIDTEKKKREKAYQARSQKTSGIGRLMVHVIEATELKACKPNGKSNPYCEISMGSQSYTTRTLQDTLNPKWNFNCQFFIKDLYQDVLCLTMFDRDQFSPDDFLGRTEVPVAKIRTEQESKGPTTRRLLLHEVPTGEVWVRFDLQLFEQKTLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9PBV5-1", "uniprot_id": "A0A8M9PBV5_DANRE", "id": "A0A8M9PBV5-1", "name": "", "aln": "--------MNGGFSIWAITPEERGKHDKQFDSLAP-TLGYLS-----------------GDQARKFFLQSGLPTSVLADIWALADIGKDGKMDRLEFSIAMKLIKLQLQGQPLPSSLPIIMKQTPTPVMTSSSRFGMGSMPNLSAMSVMPILTPIPTCPVMAP--LVPVPTLISGPLPQMPNSISVPALPNGNATLLTPTPAFPVSSGLTKSHSLLDLG------SSSSNSSS------TTSLASNSPKTS-------SSDWAVPQSSRLKYRQLFNSLDKLMSGYLSGPQVRNALTASNLTQTQLATIWFLADVDRDGQLRAEEFILAMHLVEMAKTGRPLPLTLPPDLVPPSLR-----TTKSCDLLN------GPVP-LISTELIEPELPQKNKSNVSYEDKLRENFQRGNAELEKRRLALQEQQRREEERRREEERREEEKRQQKEREERERREREAREMEIRRQREEERRMERQRELERQREEERLKELERRE----EAERQRRREWEKSKRVELQTQKEKEQNDIQRLKDRKRSLEIELEAVGNKHKQISSQLRDAKSKRQGQWAELELINQRRDVCITDINSLQLQFDEMQRQLNQLGPEKQRLADRLVHFTQN-ISSPL-INDVKQSVCEKDRSCRKLKEQLDVLERETTAKLSQMEQYNKEIKFVEMDDCVLQGLLSLLGCLTNLFLLIKELRQKQSQQQDVLEQLRRVRSDKLKELQRHRKEEEERKRKKEEEAARQAQLEQERLEQEEAERQRKLAQEREAKLREEQQRQALARLLEAQEQARAKEEKRRAEEKERNELDVHTQSSLPFNSTENNILQPVVIPEVTCSSLTTYRALYPFTARNSDELTLEADCFIQVD-----ESTVRETGWLYGSYSGNRGWFPESYAERCSKD------------------------------------SQTQPTAAETESTAP-------------------SANYPGIPRVDIEGP-----------------------------TPTHTPVS---------TNTQHSQAVALCEWSAKTDSHLGFCKDDIITVLEKQENWWYGELKEKRGWFPC-----SHVSVVTT--------NNTQSEPLYSSVEEIEVSDSGLLD---------------EYVALYTYESPESGDLTFSAEDVVLVTEKEGEWWRGCIGDQTGLFPSNYVKPKE-PDTASSAVPS----KKPEIAQVTTVSPATTPEQLSLTPGQLIVVLHKNSNSWWLGELQARGKKRKKGWFQSSNVRLLEAN--SGKITPA---------PQPLCQVIAMYDYKAANKDEMSFQKGQLITVLNKDNPDWWKGEVAGVTGLFPTNYVKMTTECDPSQQWCADLLSLDSMCTEERKRQGYIHELIQTEESYLEDLELAVEVFYKPMAESGRLTEAEISMIFVNWRELIMCSTKLLKALRVRKKTAGERMPVQVVGDILSSELSHMQAYIRFCSCQLNAAALLQQKTDKSLDFKLFLKKIASNYRCKGMPLSSFLLKPMQRITRYPLLIKNILENTPPAHADHSNLQAALEQAEELCSQVNEAVREKENSDRLEWIQNHVLCDGVIEHLVFNSLTNCLGPRKLLHSGKLHKTKSSKELWALLFNDFLLLTYTSKQFSSSP--DKLFNPNSNTQYKMYKTPVFLNEVLVKMPSDPSSDDPVFHISHIDRVYTLKTDTINERTTWVQKIKAASDHFIETEKLKREKAYQARSQKNSGIGRLLVTVLEATELKPCKPNGKSNPYCELTMGAQCYTSRHQPDTLNPKWSFNCQFFIKDLYQDVLCLTVFERDQFSPDDFLGRTEVPVATIKKDQDGKGPLVRRLLLHEVPTGEVKVRLDLQLYEQTPHV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9ND00-1", "uniprot_id": "M9ND00_DROME", "id": "M9ND00-1", "name": "", "aln": "--------MNSAVDAWAVTPRERLKYQEQFRALQP-QAGFVT-----------------GAQAKGFFLQSQLPPLILGQIWALADTDSDGKMNINEFSIACKLINLKLRGMDVPKVLPPSLLSS--LTGDVPSMTPRGSTSSLSPLDPLKGIVPAVAP--------VVPVVAPPVAVATVISPPGVSVPSGPTPPTSNPPSRHTSISERAPSIESVNQG-----------------------------------------EWAVQAAQKRKYTQVFNANDRTRSGYLTGSQARGVLVQSKLPQVTLAQIWTLSDIDGDGRLNCDEFILAMFLCEKAMAGEKIPVTLPQEWVPPNLRKIKSRPGSVSGVVSRPGSQPASRHASVSSQSGVGVVDADPTAGLPGQNKRKENYVKGQAELDRRRKIMEDQQRKEREE-----------RERKEREEADKREKARLEAERKQQEELERQLQRQREIEMEKEEQRKRELEAKEAARKELEKQRQQEWEQARIAEMNAQKEREQERVLKQKAHNTQLNVELSTLNEKIKELSQRICDTRAGVTNVKTVIDGMRTQRDTSMSEMSQLKARIKEQNAKLLQLTQERAKWEAKSKASGAALGGENAQQEQLNAAFAHKQLIINQIKDKVENISKEIESKKEDINTNDVQMS---------------------------ELKAELSALITKCEDLYKEYDVQRTSVLELKYNRKNE------------------------------------------------------TSVSSAWDTGSSSAWEETGTTVTDPYAVASNDISALAAPAVDLGGPAPEGFVKYQAVYEFNARNAEEITFVPGDIILVP-----LEQNAEPGWLAGEINGHTGWFPESYVEKLEVGEVAP------------------------------VAAVEAPVDAQVATVAD-------------------------------------------------------------TYNDNINTSSIPAASADLTAAGDVEYYIAAYPYESAEEGDLSFSAGEMVMVIKKEGEWWTGTIGSRTGMFPS-----NYVQKADVGTASTAAAEPVESLDQETTLNGNAAYTAAPVEAQ-------------EQVYQPLPVQEPSEQPISSPGVGAEEAHEDLDTEVSQINTQSKTQSSEPAESYSRPMSRTSSMTPGMRAKRSEIAQVIAPYEATSTEQLSLTRGQLIMIRKKTDSGWWEGELQAKGRRRQIGWFPATYVKVLQGGRNSGRNTPVS-GSRIEMTEQILDKVIALYPYKAQNDDELSFDKDDIISVLGRDEPEWWRGELNGLSGLFPSNYVGPFVTSEIKP----------DPGACSRRSKGIQRLWQQWRGCDIDQAAQHGDASNNKLRG-------------------------IIQAVHITKRRDGQLMG---------------CAYVRFECNELLAKSMLQENGNQLVGKAVVVDWQPELPKKRFRQWRCW---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O54916-1", "uniprot_id": "REPS1_MOUSE", "id": "O54916-1", "name": "RalBP1-associated Eps domain-containing protein 1", "aln": "-MEG-----------LTLSDAEQKYYSDLFSYCDIESTKKV----------------VVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSG-------------------------------------------------------------------------------------------------------------------------------------------------------FPLRVESINTVKDLPLPRFVASKNEQESRLAASYSSDSENQGSYSGVIPPPPGRGQVKKGPGSHDAVQP-RPSAEQQ-EPVSPVVSPQQSPPTSP-------------------------------------------------------------HTWRKHSRHPSGGNSERP-----------------LTGPGPFWSPFGDAQAGSSAGDAVWSGQSPPPPQDNWVSFADTPPTSALLTMHPASVQDQTTVRTVASAATANEIRRQSSSYEDPWKITDEQRQYYVNQFKTIQPDLNGFIPG--SAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGEQPGEVGYSGSPAEAPPSKSPSMPSLNQTWP-------------------------------ELNQSSEQWETFSERSSSSQTLTQFDSN------------------------------------------------------------------------------------------------IAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTSSDHTNPT----------------------------------------------------------------------------SPLLVKPSDLSE------------------------------------------------------------------------------------ENKINSSVKFPSGNTV-DGYSSSDSFPSDPEQIGSSVTRQRSHSGTSPD---NTAPP--------------PPPPRPQPSHSRSSSLDMNRTFAVT-------------TGQQQAGVVAHPPAVPPRPQPSQAPGPSVHRPVDADGLITHTSTSPQQIPEQPN----------------FADFSQFEVFAASNVSEEQDSEAEKHPEVLPAEKASDPSSSLRA----------AQADSKAEEKTATNVPANVSKGTTPLAPPPKPVRRRLKSEDE-LRPDVDEHTQKTGVLAAVLTSQPSIPRSVGKDKKAIQASIRRNKETN--------------TVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LDV5-1", "uniprot_id": "A0ABK0LDV5_RAT", "id": "A0ABK0LDV5-1", "name": "", "aln": "-MEG-----------LTLSDAEQKYYSDLFSYCDIESTKKV----------------VVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSG-------------------------------------------------------------------------------------------------------------------------------------------------------FPLRVESINTVKDLPLPRFVASKNEQESRHAASYSSDAENQSAYAGVIPPPPGRGQVKKAPGSHDAAQP-RPSADQQ-EPASPVVSPQQSPPTSP-------------------------------------------------------------HTWRKHNRHPSGGNSERP-----------------LAGPGPFWSPFGDAQSGSSAGDAVWSGHSPPPPQENWVSFADTPPTSALLTMHPASVQDQTTVRTVASATTANEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPG--SAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYPGSPAEAPPSKSPSMPSLNQTWP-------------------------------ELNQSSEQWETFSERSSSSQTLTQFDSN------------------------------------------------------------------------------------------------IAPADPDTAIVHPVPIRMTPSKIHMQEMELKRSSGDHTNPT----------------------------------------------------------------------------SPLLVKPSDLSE------------------------------------------------------------------------------------ENKINSSVKFPSGNTVADGYSSSDSFPSDPEQIGSNGARQRSHSGASPD---NTAPP--------------PPPPRPQPSHSRSSSLDMNRTFAVA-------------TGQQQAGVVTHPPAVPPRPQPSQAPGPSVHRPVDADGLITHTSTSPQQIPEQPN----------------FADFSQFEVFAASNVSEEQDSEAEKHPEVLPAEKASDPSSSLRV----------AQADSKIEEKTAAGVPANVSKGTTPLAPPPKPVRRRLKSEDE-LRPDVDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETN--------------TVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2B7S1-1", "uniprot_id": "A0A8M2B7S1_DANRE", "id": "A0A8M2B7S1-1", "name": "", "aln": "-MES-----------LTLSDVEQKYYSELFLSCDVDNAKKV----------------ASNGKVLELFRAAQLSNEVVLQITELCGATRLGHFGRSQFYIALKLIALAQSG-------------------------------------------------------------------------------------------------------------------------------------------------------LPLRLESLNTVRDLPLPRFVMGKNEQETRHMVMFT-DAENQG---PFLPRPPGRVQAKKVS-AHEMIQPCVPTADPQPDTTSPVVSPHQSPPTSP-------------------------------------------------------------LAWRKHKRQASGGNVDRQ-----------------PSVPGVVWPHFREAQPGPVPGDGMWSAHSPPPVQESWVSFTDTPPSSTLPMHPPSAQTESSTVRTVPSAMTTNEIQRQTSGYDDPWKITDEQRQYYINQFKTIQADLTGLIPG--SAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLDDSAGVPEPAPEVGFSASPVEVTPNKSPSMPSLNQNWP-------------------------------ELNQSNEQWETFSERSSSSQTLTQFDSN------------------------------------------------------------------------------------------------IAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTHPT----------------------------------------------------------------------------SPLMTKPPELSD------------------------------------------------------------------------------------ETKLAAAIKFP-GTAVGDGYSSSDSFTSDQEPISSAVNRQRSHSGTSPEGLKVVAPP--------------PPPPRPHASHSRSSSLDMNRNFAAVPA-----------AGSQQAGVVAFPPAVPPRPLPTQTSVPHGHRSVEGDGLPAHTSTSPQQMPEQPN----------------FADFSQFKAFAVDQPADDGENPSDGG----QAERLPEAAGTMRT----------AKNDVQAEERNATTVNS--AKVSTPLAPPPKPVRRRLKSEDE-LRPDVDDLPQKSNVIATVLATQPSIPRSLGKDKKAIQASIRRNKETN--------------TVLARLNSELQQQLKDLLEERISLEVQLEQLRPFSHL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q80XA6-1", "uniprot_id": "REPS2_MOUSE", "id": "Q80XA6-1", "name": "RalBP1-associated Eps domain-containing protein 2", "aln": "-MEVAAGGGCGAGPPLLLSDSEQQCYSELFARCAGAASGGPGPGPPEATRVAPGTATAAAGPVADLFRASQLPPETLHQITELCGAKRVGYFGPTQFYVALKLIAAAQAG-------------------------------------------------------------------------------------------------------------------------------------------------------LPVRTESIK--CELPLPRFVMSKNDGEIRFGN--------PAELHGPKVQIP------YLTTEKNSFKRMDN-EDKQ-ETQSPTMSPLASPPSSP-------------------------------------------------------------PHYQRVSLSHGYSKLRS-----------------------------GTEQMHPAPYE-RQPIGQPEGPS------SEGPGAKPFRR-------QASLIRSFSVEREPQENNSNYP--DEPWRITEEQREYYVNQFRSLQPDPSSFISG--SVAKNFFTKSKLSIPELSYIWELSDADCDGALTLSEFCAAFHLIVARKNGYPLPEGLPPTLQP----EYLQAAFPK-------SKWECAIFDSYSESMP-ANQ---------------------------------------------------QSCDLNRMEKT------------------------------------------------------------------------------------------------SVKDVADFPVPT---------------QDVTTADDKQALKS----------------------------------------------------------------------------TVNESLPKDVSE------------------------------------------------------------------------------------DTATSKDYNSLKARPRSRSYSSTS--------IEEAMKR-------------GEDPP--------------TPPPRPQKTHSRASSLDLNKVFLPS-------------APAANSGLLPPPPALPPRPCPTQ----------------------SEPVSEADL----------------HSQLN----------------------------RAPSQAAESSP----------TKMDAPHAQP------------------PSKPIRRKFRPENQTTESQEPAAAVGGAVSAAMVKPHPTVQKQSSKQKKAIQTAIRKNKEAN--------------AVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AED1-1", "uniprot_id": "A0A8I6AED1_RAT", "id": "A0A8I6AED1-1", "name": "", "aln": "-MEVAAGGGGGAGPPLLLSDSEQQCYSELFARCAGAASGGPGPGPLEATRVAPGILTAAAGPVADLFRASQLPPETLHQITELCGAKRVGYFGPTQFYVALKLIAAAQAG-------------------------------------------------------------------------------------------------------------------------------------------------------LPVRTESIK--CELPLPRFVMSKNDAEMRVGN--------PAELHGTKVQIP------YLTSEKNSFKRLDD-EEKQQETPSPRMSPLASPPSSP-------------------------------------------------------------PHYQRVPLSHGYSKLRS-----------------------------GTEQMHPAPYESRQPIGQPEGPS------SEGPGTKPFRR-------QASLIRSFSVERELQENNSNYP--DEPWRITEEQREYYVNQFRSLQPDPSSFISG--SVAKNFFTKSKLSIAELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQP----EYLQAAFPK-------SKWECVIFDSYSESMP-ANQ---------------------------------------------------QSCDLNRMEKT------------------------------------------------------------------------------------------------SVKDMADFPVST---------------QDVTTGDDKQALKS----------------------------------------------------------------------------TVNESLPKDVSE------------------------------------------------------------------------------------DTATSKDCNSLKARPRSRSYSSTS--------IEEAMKR-------------GEDPP--------------TPPPRPQKTHSRASSLDLNKVFQPS-------------VSAANSGLLPPPPALPPRPCPTQ----------------------AEPASEADL----------------YPQMN----------------------------RAPSQAAESSP----------TKKDVPHAQP------------------PSKPIRRKFRPENQTTEGQESAAVVGGAAPAAMVKPHPTVQKQSSKQKKAIQTAIRKNKEAN--------------AVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2B9B6-1", "uniprot_id": "A0A8M2B9B6_DANRE", "id": "A0A8M2B9B6-1", "name": "", "aln": "-MDPGSAGG----TFMSLSDTEQRCYSGLYALCQPDSSGIP-----------------AAGKVAELFRASQLPAETLHQVMEVCGAKRLGFFGCGQFYAALKLLAAAQAG-------------------------------------------------------------------------------------------------------------------------------------------------------LPVRLESIA--GELPLPVFVGITNELDTRYANHLSTSESQPHTLGSVPASAP------RPPTDRAVLRHPDTSMDKQEAWSPPRSPPSISPPRSP-------------------------------------------------------------SAYR----SLTYSAQRN-----------------------------GTDTLL--AYDGKMPGRPSVPQE------NASPGHYSFKLQP----EQPSITRVASVERLVERVEVDYS--DDPWRITEEQREYYTNQFRSLQPDLNALIMG--AVAKNFFTKSKLPIPELSHIWELSDVDKDGALTFPEFCTAFHLIVARKNGYLLPETLPASLRPGFQEPVVTAAPSE-------ATQPLIVFDDN--MMPGANQLE------------------------------------------------IGSVDLQVTSRP------------------------------------------------------------------------------------------------GVTTKQDTRDES---------------RKPEISPKRVPEPH----------------------------------------------------------------------------EKPMQRVSALKP------------------------------------------------------------------------------------DSPQELDAN-MKSRTRPRSYSSTS--------IDDAMKK-------------VEEPP--------------TPPPRPQKSHSRASSLDLNKLLQQG-------------TPGAKSGWLPPPPALPPRPPATQIF-----------SFLPGLEKSSQKAVQQPN----------------FADFSRFREEQESGV------------------RAGLSTEDLLP----------PKSDCSLVHQGHA---------------PQKPMRRKLHPESQSATPPLTTPYS----AATLTKPT---QRPPPKQKREIQMAIRKNRETN--------------AVLTRLNSELQQQLKVVHGERLTLETQLESMRPVAST----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P39013-1", "uniprot_id": "END3_YEAST", "id": "P39013-1", "name": "Actin cytoskeleton-regulatory complex protein END3", "aln": "--------------MPKLEQFEIKKYWQIFSGLKPIENKVNH------------------DQVLPILYNSKLDSSVLNKIWFLADIDDDDNLDFEEFVICMRLIFDMVNK-------------------------------------------------------------------------------------------------------------------------------------------------------------------NISSVPDELPDWLIPGSKVNLIKERKKRKQIENADLPPKKEIKVDWYMSPDDLNQYEKIYNSCAKLTDGTITFNELSTKLSTK------------------------------------------------------------FFNISKTDLNKVWSLINP-------------------------------QNLPSIDRDPTFYFIHCLRQRNDLG-------------------AEIPASLPNSLAEVCNKKQLSYDLRSSQPPTKRKEEANEVDNLRDNGQNSSSDSSGSNVLSNEDSIKQKYASLTDDQVANMREQLEG----LLNYKKSEKTQGGSKLSKRINIRSITDDLDNIEQQVEVLENYLNNKRHELQALQAEIN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . :: : * : .: :.. . :. * . :*: . : : : : ", "identical_positions": 3, "similar_positions": 23, "identity": "0.16%" }, { "cls_id": "homologset.agr.SGD:S000005031", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3U7R1-1", "uniprot_id": "ESYT1_MOUSE", "id": "Q3U7R1-1", "name": "Extended synaptotagmin-1", "aln": "------------------------------------------------MEHSPEEGASP--------------------EPSGQPPATDSTRDGGSGVPPAGPGAASEALAVLTSFG----RRLLVLVPVYLAGAAGLSVGFVLFG----LALYLGWRRVRDGKERSLRAARQLLDDEERITAETLYMSHRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYMEKLLAETVAP---AVRGANPHLQTFTFTRVELGEKPLRIIGVKVHP-SQRKDQILLDLNVSYVGDVQIDVEVKKYF--------CKAGVKGMQLHGVLRVILEPLTG--------DLPIVGAVSMFFIKRPTLDINWTGMTN------LLDIPGLSSLSDTMIMDSIAAFLVLPNRLLVPLVPDLQDVAQLRSPLPRGIIRIHLLAARGLSSKDKYVKGLIEGKSDPYALVRVG-TQTFCSRVIDEELNPHWGETYEVIVHEVPGQEIEVEVFDKDPDK-----DDFLGRMKLDVGKVLQ---AGVLDNWYPLQGGQ-GQVHLRLEWLSLLPDAEKLD------------------QVLQ-WNRGITS---RPEPPSAAILVVYLD---RAQDLP--------------------------------------------------------LKKGNKEPNPMVQLSVQDVTRESKATYSTNSPVWEEAFRFFLQDPRSQELDVQVKDDSRALTLGALTLPLARLLTASELTLDQW------FQLSSSGPNSRLYMKLVMRILYLDYSEIRFPTVP---GAQDWDRESLETGSSVDAPP-RPYHTTPNSHFGTENVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKVAGKSFRTHVVREDLNPRWNEVFEVIVTSIPGQELEIEVFDKDLDKDDFLGRYKVSLTTVLNSGFLDEWLTLEDVPSGRLHLRLERLTPRPTAAELEEVLQVNSLIQTQKSSELAAALLSVFLERAEDLPLRKGTKPPSPYATITVGETSHKTKTVSQSSAPVWEESASFLIRKPHAESLELQVRGEGTGTLGSVSLPLSELLQEDQLCLDHWFALS---GQGQVLMRAQLGILVSQHSGVEAHSHSYSHSHSSSSLNDEPEALGGPTHPASPVLEVRHRLTHGDSPSEAPVGPLGQVKLTVWYH-------------SDEQKLISIIHSCRALRQNG-RDLPDPYVSVLLLPDKNRSTKRKTPQKKRTLNPEFNERFEWDLP----------------------------------------------------------------------------LDGTLRRKLDVSVKSNSSFMSRERELLGKVQLDLAEIDLS--QGAAQWYDLMDDRDKGGS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BSJ8-1", "uniprot_id": "ESYT1_HUMAN", "id": "Q9BSJ8-1", "name": "Extended synaptotagmin-1", "aln": "------------------------------------------------MERSPGEGPSPS----------PMDQPSAPSDPTDQPPAAHAKPDPGSGGQPAGPGAAGEALAVLTSFG----RRLLVLIPVYLAGAVGLSVGFVLFG----LALYLGWRRVRDEKERSLRAARQLLDDEEQLTAKTLYMSHRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYMEKLLAETVAP---AVRGSNPHLQTFTFTRVELGEKPLRIIGVKVHP-GQRKEQILLDLNISYVGDVQIDVEVKKYF--------CKAGVKGMQLHGVLRVILEPLIG--------DLPFVGAVSMFFIRRPTLDINWTGMTN------LLDIPGLSSLSDTMIMDSIAAFLVLPNRLLVPLVPDLQDVAQLRSPLPRGIIRIHLLAARGLSSKDKYVKGLIEGKSDPYALVRLG-TQTFCSRVIDEELNPQWGETYEVMVHEVPGQEIEVEVFDKDPDK-----DDFLGRMKLDVGKVLQ---ASVLDDWFPLQGGQ-GQVHLRLEWLSLLSDAEKLE------------------QVLQ-WNWGVSS---RPDPPSAAILVVYLD---RAQDLP--------------------------------------------------------LKKGNKEPNPMVQLSIQDVTQESKAVYSTNCPVWEEAFRFFLQDPQSQELDVQVKDDSRALTLGALTLPLARLLTAPELILDQW------FQLSSSGPNSRLYMKLVMRILYLDSSEICFPTVPGCPGAWDVDSENPQRGSSVDAPP-RPCHTTPDSQFGTEHVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKLAGRSFRSHVVREDLNPRWNEVFEVIVTSVPGQELEVEVFDKDLDKDDFLGRCKVRLTTVLNSGFLDEWLTLEDVPSGRLHLRLERLTPRPTAAELEEVLQVNSLIQTQKSAELAAALLSIYMERAEDLPLRKGTKHLSPYATLTVGDSSHKTKTISQTSAPVWDESASFLIRKPHTESLELQVRGEGTGVLGSLSLPLSELLVADQLCLDRWFTLSS--GQGQVLLRAQLGILVSQHSGVEAHSHSYSHS--SSSLSEEPELSGGPPHITSSAPELRQRLTHVDSPLEAPAGPLGQVKLTLWYY-------------SEERKLVSIVHGCRSLRQNG-RDPPDPYVSLLLLPDKNRGTKRRTSQKKRTLSPEFNERFEWELP----------------------------------------------------------------------------LDEAQRRKLDVSVKSNSSFMSRERELLGKVQLDLAETDLS--QGVARWYDLMDNKDKGSS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T801-1", "uniprot_id": "A0A8N7T801_DANRE", "id": "A0A8N7T801-1", "name": "", "aln": "------------------------------------------------MQKSPMS-------------------------VDDAGPNAGAAPEAADAAPTTDS-AGKHAVSVLWSFG----KCVGAFLPVYLAGYFGFSISVVLLG----LLVYIGWKHSRDGKKARLQSAMYFLENEQDVTTTRVFRSKRDLPAWVNFPDVEKVEWINKILQQAWPFVGQYLEKLLVETIAP---SIRATSAHLQTLSFTKVDLGDRAMKVVGVKAYT-EFDRRQVILDLYISYAGDVEINVEVKKYF--------CKAGVKGIQLHGKLRVILEPLIG--------DVPLVGAITMFFIRRPKLDINWTGMTN------LLDIPGLNAMSDTMIMDAIASFLVLPNRLTVPLVANLH-VAQLRSPLPRGIVRIHLLEAENLPAKDNYMKGVISGKSDPYAVLRVG-TQIFTSHHVDNNLNPQWREMYEVIVHEVPGQELELEVFDKDPDQ-----DDFLGRMKLDLGIVKK---AVLLDEWYTLKDAASGQVHLRLEWLSLLPSAERLS------------------EVLE-RNQNITVPSKTADPPSAAVLTVYLD---RAQDLP--------------------------------------------------------FKKGNKDPSPMVQISVQDTTKESRTVYGTNNPAWEDAFTFFIQDPRKQDIDIQVKDDDRALTLGSLYIPMSRLLSSPELTMDQW------FQLEKSGPASRIYITAMLRVLWLNEDAILTSPVSPIPGEGYGETEVSSGATKVTATPKRPEHTSPDSNFASEGVLRIHLVEAQSLVAKDNLMGGMMKGKSDPYVKIRVGGLAFKSQVIKENLNPVWNELYEVILTQLPGQEVEFDLFDKDIDQDDFLGRVKVSLRDLISAQFTDQWYTLNDVKTGRIHLVLEWVPKISDPIRLEQILQYNYRQSYLNKIVPSAALLFVYIERAHGLPLKKSGKEPKAGAEVSLKNVSYRTKVVNRSTSPQWDEALHFLIHNPTEDTLIVKVSHSWGQALGSLVLPVRELLEEKDLTIDRWFSLNGAMPESQILLRAELKLLDSKLAQCSDE-------------EDASHVIPSAEPTVAANSELRHRNVPVQGGEDASSTGKAQIKLSISYS-------------SEEHRLIIKVHACRNLPSSS-KEPPDSYISFILLPDKNRNTKKKTSVKKKSLKPEFNEIFEFDMS----------------------------------------------------------------------------LEEAKQKHLEVSVKNSVSFMSREKELLGKLQIDFSPLDLK--TGVSQWYDLSHETN------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0FGR9-1", "uniprot_id": "ESYT3_HUMAN", "id": "A0FGR9-1", "name": "Extended synaptotagmin-3", "aln": "------------------------------------------------MRAEE--------------------------PCAPGAPS----ALGAQRTPGPELRLSSQLLPELCTFVV---RVLFYLGPVYLAGYLGLSITWLLLG----ALLWMWWRRNRRGKLGRLAAAFEFLDNEREFISRELRG--QHLPAWIHFPDVERVEWANKIISQTWPYLSMIMESKFREKLEP---KIREKSIHLRTFTFTKLYFGQKCPRVNGVKAHTNTCNRRRVTVDLQICYIGDCEISVELQK----------IQAGVNGIQLQGTLRVILEPLLV--------DKPFVGAVTVFFLQKPHLQINWTGLTN------LLDAPGINDVSDSLLEDLIATHLVLPNRVTVPVKKGLD-LTNLRFPLPCGVIRVHLLEAEQLAQKDNFLG--LRGKSDPYAKVSIG-LQHFRSRTIYRNLNPTWNEVFEFMVYEVPGQDLEVDLYDEDTDR-----DDFLGSLQICLGDVMT---NRVVDEWFVLNDTTSGRLHLRLEWLSLLTDQEVLT------------------EDHGGLSTAILVVFLESACNLPRNPFDYLNGEYRAKKLSRF-----------------------------------------------------ARNKVSKDPSSYVKLSVGKKTHTSKTCPHNKDPVWSQVFSFFVHNVATERLHLKVLDDDQECALGMLEVPLCQILPYADLTLEQR------FQLDHSGLDSLISMRLVLRFLQVE------------------ERELGSPYTGPEALK-----------------------------------------KGPLLIKKVATNQGPKAQPQEEGP---------------------------------------TDLPCPPDP------------------------------------------ASDTKDVSRSTTTTTSATTVAT-EPTSQETGPEPKGKDSAKR--------FCEPIGEKKSPATIFLTVPGPHSPGPIKSPRPMKCPASPFAWPPKRLAPS----------------------------------------------------------MSSLNSLASSCFDLADISLNIEGG-DLRRRQLGEIQLTVRYV-------------CLRRCLSVLINGCRNLTPCT-SSGADPYVRVYLLPERKWACRKKTSVKRKTLEPLFDETFEFFVP----------------------------------------------------------------------------MEEVKKRSLDVAVKNSRPLGSHRRKELGKVLIDLSKEDLI--KGFSQWYELTPNGQPRS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZC04-1", "uniprot_id": "D3ZC04_RAT", "id": "D3ZC04-1", "name": "Extended synaptotagmin-3", "aln": "------------------------------------------------MQPEE--------------------------SCAGSAPPGPDVPERRQRSPDPEPRLSGQLLPELYSFVA---RVLFYLAPVYLAGYLGLSVTWLLLG----ALLWMWWRRNRRGKLGRLEAAFEFLEHEREFISRELRG--QHLPAWIHFPDVERVEWANKIITQIWPYLSMIMENKIREKLEP---KIREKSIHLRTFTFTKLYFGQKCPKVNGVKAHTDKCNRRKVTLDLQICYIGDCEISVELQK----------IRAGVNGVQLQGTLRVILEPLLV--------DKPFIGAVTVFFLQKPHLQINWTGLTN------LLDMPGINELSDSLLEDLIAAHLVLPNRVTVPVKKGLD-ITSLRVPLPCGVIRVHLLEAKKLAQKDNFLG--LGGKSDPYAKVSIG-LQQCRSRTVYKNLNPTWNEVFEFMVYEVPGQDLEVDLYDEDADR-----DDFLGSLQISLGDVMK---NRVVDEWFVLNDTTSGRLHLRLEWLSLLTDPEALE------------------NDSG-LSTAILVVFLENACNLPRNPFDYLNGEYRAKKLSRF-----------------------------------------------------VKNKASRDPSSYVKLSVGKKTFTSKTCPHSKDPVWSQVFSFFVHSVAAEQLCLKVLDDELECALGVLEFPLCQILSCADLTLEQC------FQLDHSGLDSLISMRLVLRFLRVG------------------ERELGSPYTGPDALK-----------------------------------------KGPLFVKKVDTNQGCKAPTLKEDL---------------------------------------TDVTSILNP------------------------------------------ASYIKGASKSTDNISVATKAPEPKPEPQETGLEPKGKDGATG--------LCESLGRKKNPATTFLTVPGPHSPGPIKSPRPMSRPAFPFAWPLTRVAPS----------------------------------------------------------MSSLNSLASSCFDLTDVSFNTESG-DCRLRRLGEIQLTVRYV-------------CLRHCLRVLVNGCRNLTPCT-SSGADPYVRIYLLPERRWASRKKTSVKQKTLEPLFDETFEFFVP----------------------------------------------------------------------------MGEVQKRSLDVAVKNSRPLGSHRRKELGKVLIDLSKQDLI--KGFSQWYELTPDGQPRS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2BIQ8-1", "uniprot_id": "A0A8M2BIQ8_DANRE", "id": "A0A8M2BIQ8-1", "name": "", "aln": "-----------------------------------------------MSASVNGVE---------PKPAPAVSQ--NGPGSPPQTPKDVTPPELELPDEEPQSS-VTEATQMGIKFA----KTFLLIFPIYLLGYLEFSFSWVLIG----LGLVFWLKRNQGSRFARVNQAMAFLEQEERAVRQTIRS--SELPPWVHFPDVERVEWLNKTVQQMWPYICQFVEKIFKETIEP---AVQGANTHLSTFTFSKIDMGDKPLRVDGVKVYTENVDKRQIIMDLQINFVGNTEIDVDIKKYY--------CRAGIKSIQLNGVLRVIMEPLLG--------DMPLVGALSVFFLKKPFLDINWTGLTN------MLDIPGVNSLCDNVIQDIINGCLVNPNKITIPLADDAL-ISKLRFPMPRGILRVHFLEGQDLLSKDTYMGGLIKGKSDPYGVIQIN-NQLFRSKIIKDSLNPRWNEVYEAIVYDGQGQVVFIELFDEDTDH-----DDFLGSLTMEIDEIQK---QQKVDEWFDLIGVPNGKLHVKAEWLSLHPTPDKLD------------------EVLSSIKADKGQ---ANDGLSSALLLVHLD---SAKNLPGVFEGQVGSGCLRERRSAGLVFCENTSALYRTMFRNPLEFNSAGLKKGAVNKAVKSGKKVTSVPNPFVQFTVGHRSFESKTRFKTIEPVWEETFTFLIHNPKCQDLEVEVKDEKHECSLGTITLPLSQLLKEKQMTMSQR------FPLKNSGPGSTLKMKMALRILSLD-------------------KLAAS-DKPSSAQ-----------------------------------------------VHRAGSVRKTSN--------------------------------------------------------------------------------------------------ATPQRPAVSEPAKTSKTQQPAPAPRTQPTPTPSPRVE--------------PVTDRKPLEESPPHLAKSGKSMSNLAISGSNLHLNSKEQTPS----------------------------------------------------------------IASDISNLAATQELQKTIQQLHNGASPGFAPLGEIELTIRHS-------------PQRNKLIVVVHKCRNLISAS-QNGSDPYVRLYLLPDKRRSGRRKTSTAKKTVNPIFDQTFEFTVS----------------------------------------------------------------------------IMELPRRTLDVAVKNGGGILAKHRGLLGKVIVEFNLEDPS--KNSTQWYELSVDGFKRPSP-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9QCZ0-1", "uniprot_id": "A0A8M9QCZ0_DANRE", "id": "A0A8M9QCZ0-1", "name": "", "aln": "----------------------------------------MLNMTEDVMTAVRGNL---------SQTAVASGQKDNGQAEPTNGAIPCSSSPVELS-EEPLSC-SSELTRTWLQFA----KTFVVIFPIYVLGYFEFSFSWLLIA----LTIFFFWKRNTNSKNTRLSRAMSIFDPDD-AVKQELDA--TELPSWVHYPDVERVEWLNKTVNQMWPYVCQFVDKLFKETIEP---AIKESNAHLSTFSFTKIDLGDKPLRINGVKVYSENVDKRQIIMDLQISYVGNTEIDVDVKRYY--------CRAGIKSIQLHGVLRVILEPLLG--------NMPLVGAFSLFFLKKPLLDINWTGLTN------ILDIPGLNGFSDQMIQDIISAYMVLPNRITVPLIGEVE-LAQLRFPMPKGVLRIYFIEAQNLEVKDTYLGGLIKGKSDPYGMLLVS-NQLFRSKTIKECLHPKWNEVYEALVYEPSGQHLEIELFDEDPDK-----DDFLGSLMIDLTELHK---EQKVDEWFDLEEVTTGKLHLRLEWLSLYSSAEKLD------------------QVQKSIRT--------NDNLSSALLIVNLD---SASNLPSVFEGSFGCGNLKERRASGLVFCENADSLCRELFS---------------------GKKVSIDPNPFVKLTVGQKTCTSKVRYKTSEPLWEETFPFLINNPQTQELEIEVKDSKHKCSLGSLQVSLASLLNEVDMTLNQQ------FPLQSSGPNSTLKLKMALRILSLE-------------------KEVTS-SHPSSVR-----------------------------------------------VRITS--QSNTC--------------------------------------------------------------------------------------------------VPPKPQATSSPTDIQPSQNP---PCTPPPDTPQ---------------------GKRGSDGSPVRLADAGRSLSSLGIGSSHKRQSHRDSTPS----------------------------------------------------------------LASDISLPCATLELQQRLQQLQNGSGLNLYPLGEVQLTVRHS-------------SQRNKLIVVVHACRNLIALN-KDGSDPYIRLYLLPDKSRSGRRKTSTLKKTLNPIYDQSFEFSVS----------------------------------------------------------------------------MVELHRRTLDIAVKNGGGLLSKNKLLLGKTLVDLGSEDIS--KGWTHWYHLTEDGAKKLMQT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0FGR8-1", "uniprot_id": "ESYT2_HUMAN", "id": "A0FGR8-1", "name": "Extended synaptotagmin-2", "aln": "MTANRDAALSSHRHPGCAQRPRTPTFASSSQRRSAFGFDDGNFPGLGERSHAPGSRLGARRRAKTARGLRGHRQRGAGAGLSRPGSARAPSPPRPGGPENPGGVLSVELPGLLAQLA----RSFALLLPVYALGYLGLSFSWVLLA----LALLAWCRRSRGLKALRLCRALALLEDEERVVRLGVRA--CDLPAWVHFPDTERAEWLNKTVKHMWPFICQFIEKLFRETIEP---AVRGANTHLSTFSFTKVDVGQQPLRINGVKVYTENVDKRQIILDLQISFVGNCEIDLEIKRYF--------CRAGVKSIQIHGTMRVILEPLIG--------DMPLVGALSIFFLRKPLLEINWTGLTN------LLDVPGLNGLSDTIILDIISNYLVLPNRITVPLVSEVQ-IAQLRFPVPKGVLRIHFIEAQDLQGKDTYLKGLVKGKSDPYGIIRVG-NQIFQSRVIKENLSPKWNEVYEALVYEHPGQELEIELFDEDPDK-----DDFLGSLMIDLIEVEK---ERLLDEWFTLDEVPKGKLHLRLEWLTLMPNASNLD------------------KVLTDIKADKDQ---ANDGLSSALLILYLD---SARNLP-------------------------------------------------------SGKKISSNPNPVVQMSVGHKAQESKIRYKTNEPVWEENFTFFIHNPKRQDLEVEVRDEQHQCSLGNLKVPLSQLLTSEDMTVSQR------FQLSNSGPNSTIKMKIALRVLHLE-------------------KRERPPDHQHSAQ-----------------------------------------------VKRPSVSKEGRK--------------------------------------------------------------------------------------------------TSIKSHMSGSPGPGGSNTAPS-TPVIGGSDKPGME------------------EKAQPPEAGPQGLHDLGRSSSSLLASPG--HISVKEPTPS----------------------------------------------------------------IASDISLPIATQELRQRLRQLENGTTLGQSPLGQIQLTIRHS-------------SQRNKLIVVVHACRNLIAFS-EDGSDPYVRMYLLPDKRRSGRRKTHVSKKTLNPVFDQSFDFSVS----------------------------------------------------------------------------LPEVQRRTLDVAVKNSGGFLSKDKGLLGKVLVALASEELA--KGWTQWYDLTEDGTRPQAMT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZJ32-1", "uniprot_id": "D3ZJ32_RAT", "id": "D3ZJ32-1", "name": "Extended synaptotagmin-2", "aln": "------------------------------------------------MSSAGGE--------------------GPEAGTGRAGGRSEP--------EAPGSALSVDLPGLLGQLA----RSFALLLPVYALGYLGLSFSWVLLA----LGLLAWCRRSRGLKASRLCRALALLEDEEQAVRLGVRA--CDLPAWVHFPDTERAEWLNKTVKHMWPFICQFIEKLFRETIEP---AVRGANAHLSTFSFTKVDVGHQPLRVNGVKVYTENVDKRQIILDLQISFVGNCEIDLEIKRYF--------CRAGVKSIQIHGTMRVILEPLIG--------DMPLVGALSIFFLRKPLLEINWTGLTN------LLDIPGLNGLSDTIILDIISNYLVLPNRITVPLVSEVQ-IAQLRFPIPKGVLRIHFIEAQDLQGKDTYLKGLVKGKSDPYGIIRVG-NQIFQSKVVKENLSPKWNEVYEALVYEHPGQELEIELFDEDPDK-----DDFLGSLMIDLIEVEK---ERLLDEWFTLDEVPKGKLHLKLEWLTLMPDAANLD------------------KVLADIRADKDQ---ANDGLSSALLILYLD---SARNLP-------------------------------------------------------SGKKINSNPNPLVQMSVGHKAQESKIRYKTSEPVWEENFTFFIHNPKRQDLEVEVKDEQHQCSLGSLRIPLSQLLASDNMTINQR------FQLSNSGPNSTLKMKIALRVLHLE-------------------KQERPPDYQHSAQ-----------------------------------------------VKRPSVSKEGRK--------------------------------------------------------------------------------------------------MPIKSQMSASPGTGGTNTAPS-TPVMGVDDKPAME------------------EKPQPPEASPLGQRDLGRSSSSLLASPS--HIAAKEPTPS----------------------------------------------------------------IASDISLPIATQELRQRLRQLENGTTLGQSPLGQIQLTIRHS-------------SQRNKLIVVVHSCRNLIAFS-EDGSDPYVRMYLLPDKRRSGRRKTHVSKKTLNPVFDQSFDFSVS----------------------------------------------------------------------------LPEVQRRTLDVAVKNSGGFLSKDKGLLGKVLVALASEELA--KGWTQWYDLTEDGTRPQVIT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0B4K6F9-1", "uniprot_id": "A0A0B4K6F9_DROME", "id": "A0A0B4K6F9-1", "name": "", "aln": "------------------------------------MSDNSPSVPLAEFTIPPDPTETEPFVPLVEVKKMNESPVVTPTTPTGNGTPPTQTTNGNSIVATKSVSDDNSIFSVFYTLG----KKVAIVGSIYLVGYMGWSVAWLIAP----VILSVARDQLAKTSEKKRDIAKASALASEKDVILARID---ELPAWVYFPDVERCEWLNKILKQVWPNANHFARTLVKETIEPNV-ALALANYKMHGFRFDRIILGTIPPRIGGVKIYDKNVDRNEIIMDLDLFYASDCDINFYLGG----------MKGGIKDFQIHGWVRVVMKPLIR--------SMPLVGGLQIFFLNNPNIDFNLVGVID------FMDMPGLSDLLRRIIVEQIGNVMVLPNKLPISLSEEVS-AVALKMPEPEGILRIHVVEAKDLMKKDISVLG--KGKSDPYAIINVG-AQEFKTQIIDNNVNPKWDYWCEACIFTTIGHYIGFSLWDYDQTMPGVQSDDVLGRASIDIASVIK---KGVVDSWLTLEDAKHGLLHVRLQWYKLTADPNDLQ------------------QILLETQLLRVT------SMSSAVLSVFID---SARHLK--------------------------------------------------------QARSSSKPDPYLVCSVNKQKQQTAMIMRDDSPVWEQGFTFLVSNPDNESLNIKIYDQKTGNDIGQYTYTLSTLLKQFNMEVIQQP-----FQLQKSGPESKLYMSLSLRILKPG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EIDKDSDALEQVAALTRSSSVKTPDVAAVSPPAFK----------------------ESQASSKRLSAESPISEEDPVAATKISPAMSAS--------------------------------------------------------------------TSSEKPISELATSVLTHRFPDSTSSPGEHGLGRMQLSIRYS-------------AQRQKLDVTIHKIQKIPLRDPSNIPDPYVKLYLLPGRTKESKRKTSVIKDNCNPVYDASFEYLIS----------------------------------------------------------------------------IAELRQTELEVTVCTQKGFLSGGSPIIGMLKIPLDDAEITTQTGLNSWFDLQPEIRHE----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48231-1", "uniprot_id": "TCB2_YEAST", "id": "P48231-1", "name": "Tricalbin-2", "aln": "------------------------------------MSPNSSKTRTDQISSMPGINEATKVESK-NVVKDAVPIKSEVETNGTSIVREKQDPSYVGWKQVGGWEEKDELTSEDLLVDVNKDTFLGNLLPDKFYGDWYHEVAILIIAGLCSFVLGYFKFSLASVLIVMLTTGMLYRTSSKKYRESLRDLAQKEQTVEKITSDYESVEWLNTFLDKYWPIIEPSVSQQIVDGTNTALSENVAIPKFIKAIWLDQFTLGVKPPRIDAIKTFQ-NTKSDVVVMDVCLSFTPHDMSDLDAKQCRNYVNSNVVLKAKIFGMDIPVSVADIFFQVFVRFRFQLMTTLPLVETINIQLLEVPEVDFISRLLGNSVFNWEILAIPGLMRLIQKMAFKYLSPVLLPPFSLQLNIPQLLS-----KTGLPIGVLEIKVKNAHGLR----KLVGMIKKTVDPYLTFELSGKIVGKTKVFKNSANPVWNESIYILLQSFTDP-LTIAVYDKRETLS----DKKMGTVIFNLNKLHANHYHKNEKVHFLRNSKPVGELTFDLRFFPTIEPKKLLNGDEEPLPDMNTGITKITIRELKGLDELSDKKFVFAELYVNAELVMTTKKEKRTAHLKWN-----------------------------------------------SDYYSVVTDRRKTICRFVLKDQSGKVISSSVQPLNHLIDRTEVNKEWIPLRNGKGELKVTTYWRPVDIDLGLKSVGYTTPIGMLRVFINKAENLRNPDSLGKISPYAKVSVNGVARGRTNERIETLNPIWN-----QSIYVSVTSPLQKVSIDCFGIDTNGDDHN------------------------------LGSLNIQTQNIYHKDNDDKYTIFIDNAPRTGNLIGKKGVKGTVTYYLSFYPVVPVLSLEEAKEVDEINEKKDKLEKQ-------------------------------------KSTLDDKNISKEEKERIKKEEFRLTEKYDMYSYKMKLDLDELLQYNAGVLGVTVLGGELPQPGLYVQTFFDSCGYAAITSAKNAIRTIKTGWSGDFMIKELEWSVTTFRVTKT---------------------------------------KDANKAENFICEVNIPTIELVRNCYYKPSVLNLIGKKSAKLLVQVSWFPVTATELPQSDLITNSGDLKITAKSAENLIGVNKNGYSDPYVEFFLN-EKSTSPFFKTAVQKKTLNPTWNESKTIEVSNRVNDYLTINVKDYESTNSNRSIGKAVVPLSTIDPESDTTFNIPLVGPKGEDGGVLHLEFEFEPRYTTNVVKREAGLGNFATKGLGTGIKAGSTVFALGTNVVSTGLGTIDKVKAGVFGGKKSTTTGDKKSEEKQ---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . * .. :: : . . . . .* * ** *. : : ** . : . : : : :. .* :: .:* . : :*: : : . .. :. : ..:: : :: : *:: . : ::. * ::: : : :: **: . : . : :: * : : : : * *::.: . .. * : . *** . :. :: . * * : . : . ::* *. :* : : : . * : . .: * . . : .* : . : . : . :: : : :* : : : : * . : : : * . . . ..: : : * : . : .*.*: . * : :* : . .* :: :. : * : . : :. : . . . ", "identical_positions": 40, "similar_positions": 163, "identity": "2.87%" }, { "cls_id": "homologset.agr.SGD:S000005032", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y7L4-1", "uniprot_id": "A0A8I5Y7L4_RAT", "id": "A0A8I5Y7L4-1", "name": "DNA topoisomerase 2", "aln": "MAKSS-------LAGVDGALTWV-----NNAAKKEELETANKNDSSKKLSVERVYQKKTQLEHILLRPDTYIGSVEPLTQLMWVYDEDVG-MNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFD-GEDYTCITFQPDLAKFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLD-------ETGVA----LKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHG-FLEEFITPIVKASKNK---QELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPAVDDNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLEGLDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTPALISDYKEYHTDTTVKFVVKMT--EEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKKDLIQMLVQRGYE--SDPVKAWK-----EAQEKAAEEEDAQNPHD---DSSSDSGTPS-GPD-----------FNYILNMSLWSLTKEKVEELIKQRDTKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQEREDILAGMSGKAVKGKVGKAKVKKLQLEETMPSPYGRRIVPEIT-AMKADASRKLLKKKKGDPDTTVVKVEFDEEFSGTPAEGTGEETLTPSAPVNKGPKPKREKKEPGTRVRKTPASTGKPNTKKVKKRNPWSDDESKSESDLEEAEPVVIPRDSLLRRAAAERPKYTFDFSEEEEDDADDDDD-NNDLEELKVKASPITNDGEDEFVPSDGIDKDEYAFSPGKSKATPEKSSHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDTTSVFAPSFGLKQTDKVPSQTVAAKKGKAPSDAAAPKAKRAPRQRKVVEPANSDSDSELGNIPKKTAAPKGKGRGAKKRKASGSENEGDYNPGRKPSKTASKKPKKTSFDQDSDVDIFPSDFTSEPPALPRTGRARKEVKYFAESDEEED-VDFAMFN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64511-1", "uniprot_id": "TOP2B_MOUSE", "id": "Q64511-1", "name": "DNA topoisomerase 2-beta", "aln": "MAKSS-------LAGSDGALTWV-----NNATKKEELETANKNDSTKKLSVERVYQKKTQLEHILLRPDTYIGSVEPLTQLMWVYDEDVG-MNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFD-GEDYTCITFQPDLSKFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLD-------ETGVA----LKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVSKLIEVVKKKNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHG-FLEEFITPIVKASKNK---QELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPAVDDNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLEGLDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTPALISDYKEYHTDTTVKFVVKMT--EEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKKDLIQMLVQRGYE--SDPVKAWK-----EAQEKAAEEEDSQNQHD---DSSSDSGTPS-GPD-----------FNYILNMSLWSLTKEKVEELIKQRDTKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQEREDILAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIVPEIT-AMKADASRKLLKKKKGDPDTTVVKVEFDEEFSGTPAEGTGEETLTPSAPVNKGPKPKREKKEPGTRVRKTPTSTGKTNAKKVKKRNPWSDDESKSESDLEEAEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDAAAADD-SNDLEELKVKASPITNDGEDEFVPSDGLDKDEYAFSSGKSKATPEKSSNDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDTASVFAPSFGLKQTDKLPSKTVAAKKGKPPSD-TAPKAKRAPKQKKIVETINSDSDSEFG-IPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKPSKTASKKPKKTSFDQDSDVDIFPSDFTSEPPALPRTGRARKEVKYFAESDEEED-VDFAMFN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02880-1", "uniprot_id": "TOP2B_HUMAN", "id": "Q02880-1", "name": "DNA topoisomerase 2-beta", "aln": "MAKSGGCGAGAGVGGGNGALTWVTLFDQNNAAKKEESETANKNDSSKKLSVERVYQKKTQLEHILLRPDTYIGSVEPLTQFMWVYDEDVG-MNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFD-GEDYTCITFQPDLSKFKMEKLDKDIVALMTRRAYDLAGSCRGVKVMFNGKKLPVNGFRSYVDLYVKDKLD-------ETGVA----LKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHG-FLEEFITPIVKASKNK---QELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSTLARLLFPAVDDNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTPALISDYKEYHTDTTVKFVVKMT--EEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKKDLIQMLVQRGYE--SDPVKAWK-----EAQEKAAEEDETQNQHD---DSSSDSGTPS-GPD-----------FNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQEREDVLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEIT-AMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSD-TVPKPKRAPKQKKVVEAVNSDSDSEFG-IPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAESDEEEDDVDFAMFN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q01320-1", "uniprot_id": "TOP2A_MOUSE", "id": "Q01320-1", "name": "DNA topoisomerase 2-alpha", "aln": "MELSPLQPVN---------------------ENMLMNK-KKNEDGKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQMWVYDEDVG-INYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNVISIWNNGKGIPVVEHKVEKIYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQTWMDNMGRAGDMELKPFS-GEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNSLPVKGFRSYVDLYLKDKVD-------ETGNS----LKVIHEQVNPRWEVCLTMSERGFQQISFVNSIATSKGGRHVDYVADQIVSKLVDVVKKKNKGGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQIQLNKKCSAVKHTKIKGIPKLDDANDAGSRNSTECTLILTEGDSAKTLAVSGLGVVGRDKYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLRHR-FLEEFITPIVKVSKNK---QEIAFYSLPEFEEWKSSTPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQVDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQSTSYLTYNDFINKELILFSNSDNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLRFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLLDGEEPLPMLPSYKNFKGTIEELASNQYVINGEVAILDSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPSLITDYREYHTDTTVKFVIKMT--EEKLAEAERVGLHKVFKLQSSLTCNSMVLFDHVGCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESSKLNNQARFILEKIDGKIVIENKPKKELIKVLIQRGYD--SDPVKAWK-----EAQQKVPDEEENEESD--TETSTSDSAAEA-GPT-----------FNYLLDMPLWYLTKEKKDELCKQRNEKEQELNTLKQKSPSDLWKEDLAVFIEELEVVEAKEKQDEQVGLPGKAGKAKGKKAQMCA----DVLPSPRGKRVIPQVTVEMKAEAEKKIRKKIK------------SENVEGTPAE-DGAEPGSLRQRIE-----KKQKKEPG--AKKQTTLPFKP-VKKGRKKNPWSDSESDVSS--NESNVDVPPRQKEQRSAAA-KAKFTVDLDSDEDFSGLDEKD------------------EDEDFLPLDAT--------PPKAKIPPKNTKKALKTQ--GSSMSVVDLESD-VKDSVPASPGVPAADFPAETEQSKPS-KKTVGVKKTATKSQSSVSTAGTKKRAAPKGTKSDSALSAR-------VSEKPAPAKAKNS--RKRKPSSSDSSDSDFERAISKGATSKKAKGEEQD-------FPVDLEDTIAPRAKSDRARKPIKYLEESDDDDD-----LF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41516-1", "uniprot_id": "TOP2A_RAT", "id": "P41516-1", "name": "DNA topoisomerase 2-alpha", "aln": "MELSPLQPVN---------------------ENMLLNK-KKNEDGKKRLSVERIYQKKTQLEHILLRPDTYIGSVELVTQQMWVYDEDVG-INYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTMMR-NNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQTWMDNMGRAGDMELKPFS-GEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNRLPVKGFRSYVDMYLKDKVD-------ETGNA----LKVVHEQVNPRWEVCLTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVSKLVDVVKKKNKGGVAVKADQVKNHMWIFGNAVIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQIQLNKKCSAVKHNRIKGIPKLDDANDAGSRNSAECTLILTEGDSAKTLAVSGLGVVGRDKYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLRHR-FLEEFITPIVKVSKNK---QEIAFYSLPEFEEWKSTNPNHKKWKVKYYKGLGTSTSKEAKEYFANMKRHRIQFKYSGPEDDAAISLAFSKKQVDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTMYLTYNDFINKELILFSNSDNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPSKDDHTLRFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLLDGEEPLPMLPSYKNYKGTIEELASNQYVINGEVAILNSTTIEITELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREYHTDTTVKFVIKMT--EEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESSKLNNQARFILEKIDGKIVIENKPKKELIKVLIQRGYD--SDPVKAWK-----EAQQKVPEEEENEENEE-SESESTSPAAES-GPT-----------FNYLLDMPLWYLTKEKKDELCKQRDEKEQELNTLKKKTPSDLWKEDLAAFVEELEVVEAKEKQDEQVGLPGKGVKAKGKKAQIS-----EVLPSPVGKRVIPQVTMEMRAEAEKKIRRKIK------------SENVEGTPAE-DGAEPG-LRQRLE-----KRQKREPGTRAKKQTTLPFKP-IKKAQKQNPWSDSESDMSS--NESNFDVPPREKEPRIAAT-KAKFTADLDSDDDFSGLDEKD------------------EDEDFFPLDDT--------PPKTKMPPKNTKKALKPQ--KSSTS-VDLESD-GKDSVPASPGASAADVPAETEPSKPSSKQTVGVKRTITKGQSLTSTAGTKKRAVPKETKSDSALNAH-------VSKKPAPAKAKNS--RKRMPSSSDSSDSEFEKAISKGATSKKLKGEERD-------FHVDLDDTVAPRAKSGRARKPIKYLEESDDD-------LF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11388-1", "uniprot_id": "TOP2A_HUMAN", "id": "P11388-1", "name": "DNA topoisomerase 2-alpha", "aln": "MEVSPLQPVN---------------------ENMQVNKIKKNEDAKKRLSVERIYQKKTQLEHILLRPDTYIGSVELVTQQMWVYDEDVG-INYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQTWMDNMGRAGEMELKPFN-GEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKLD-------ETGNS----LKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTLQPKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQVQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDKYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLRHR-FLEEFITPIVKVSKNK---QEMAFYSLPEFEEWKSSTPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPLPMLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGTEKTPPLITDYREYHTDTTVKFVVKMT--EEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQRGYD--SDPVKAWK-----EAQQKVPDEEENEESDNEKETEKSDSVTDS-GPT-----------FNYLLDMPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKEDLATFIEELEAVEAKEKQDEQVGLPGKGGKAKGKKTQMA-----EVLPSPRGQRVIPRITIEMKAEAEKKNKKKIK------------NENTEGSPQE-DGVELEGLKQRLE-----KKQKREPGTKTKKQTTLAFKP-IKKGKKRNPWSDSESDRSS--DESNFDVPPRETEPRRAAT-KTKFTMDLDSDEDFSDFDEKT------------------DDEDFVPSDAS--------PPKTKTSPKLSNKELKPQ--KSVVS--DLEADDVKGSVPLSSSPPATHFPDETEITNPVPKKNVTVKKTAAKSQSSTSTTGAKKRAAPKGTKRDPALNSG-------VSQKPDPAKTKNR--RKRKPSTSDDSDSNFEKIVSKAVTSKKSKGESDD-------FHMDFDSAVAPRAKSVRAKKPIKYLEESDEDD------LF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P15348-1", "uniprot_id": "TOP2_DROME", "id": "P15348-1", "name": "DNA topoisomerase 2", "aln": "-----------------------------------------MENGNKALSIEQMYQKKSQLEHILLRPDSYIGSVEFTKELMWVYDNSQNRMVQKEISFVPGLYKIFDEILVNAADNKQRDKSMNTIKIDIDPERNMVSVWNNGQGIPVTMHKEQKMYVPTMIFGHLLTSSNYNDDEKKVTGGRNGYGAKLCNIFSTSFTVETATREYKKSFKQTWGNNMGKASDVQIKDFN-GTDYTRITFSPDLAKFKMDRLDEDIVALMSRRAYDVAASSKGVSVFLNGNKLGVRNFKDYIDLHIKNTDD-------DSGPP----IKIVHEVANERWEVACCPSDRGFQQVSFVNSIATYKGGRHVDHVVDNLIKQLLEVLKKKNKGGINIKPFQVRNHLWVFVNCLIENPTFDSQTKENMTLQQKGFGSKCTLSEKFINNMSKSGIVESVLAWAKFKAQNDIAKTG-GRKSSKIKGIPKLEDANEAGGKNSIKCTLILTEGDSAKSLAVSGLGVIGRDLYGVFPLRGKLLNVREANFKQLSENAEINNLCKIIGLQYKKKYLTEDDLKTLRYGKVMIMTDQDQDGSHIKGLLINFIHTNWPELLRLP-FLEEFITPIVKATKKN---EELSFYSLPEFEEWKNDTANHHTYNIKYYKGLGTSTSKEAKEYFQDMDRHRILFKYDGSVDDESIVMAFSKKHIESRKVWLTNHMDEVKRRKELGLPERYLYTKGTKSITYADFINLELVLFSNADNERSIPSLVDGLKPGQRKVMFTCFKRNDKREVKVAQLSGSVAEMSAYHHGEVSLQMTIVNLAQNFVGANNINLLEPRGQFGTRLSGGKDCASARYIFTIMSPLTRLIYHPLDDPLLDYQVDDGQKIEPLWYLPIIPMVLVNGAEGIGTGWSTKISNYNPREIMKNLRKMINGQEPSVMHPWYKNFLGRMEYVSDGRYIQTGNIQILSGNRLEISELPVGVWTQNYKENVLEPLSNGTEKVKGIISEYREYHTDTTVRFVISFAPGEFERIHAEEGGFYRVFKLTTTLSTNQMHAFDQNNCLRRFPTAIDILKEYYKLRREYYARRRDFLVGQLTAQADRLSDQARFILEKCEKKLVVENKQRKAMCDELLKRGYR--PDPVKEWQRRIKMEDAEQADEEDEEEEEAAPSVSSKAKKEKEV-DPEKAFKKLTDVKKFDYLLGMSMWMLTEEKKNELLKQRDTKLSELESLRKKTPEMLWLDDLDALESKLNEVEEKERAEE-QGINLKTAKALKGQ----------KSASAKGRKVKSMGGGAGAGDVFP---------------------DPDGEPVEFKITEEIIKKMAAA-------AKVAQAAKEPKKPKEPKEPKVKKEPKGKQIKAEPDASGDEVDEFDAMVEGGSK-----TSPKAKKAVVKKEPGEKKPRQKKE------------------NGGGLKQSKID----------FSKAKAKKSDDDVEEVTPRAERPGRRQASKKIDYSSLFSDEEEDGGNVGSDDDGNASDDDSP--KRPAKRGREDESSGGAKKKAPPK---------------------------------KRRAVIESDDDD--------------------------------------------------IEIDEDDDDDSD------FNC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06786-1", "uniprot_id": "TOP2_YEAST", "id": "P06786-1", "name": "DNA topoisomerase 2", "aln": "-------------------------------------------MSTEPVSASDKYQKISQLEHILKRPDTYIGSVETQEQLQWIYDEETDCMIEKNVTIVPGLFKIFDEILVNAADNKVRDPSMKRIDVNIHAEEHTIEVKNDGKGIPIEIHNKENIYIPEMIFGHLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTEFILETADLNVGQKYVQKWENNMSICHPPKITSYKKGPSYTKVTFKPDLTRFGMKELDNDILGVMRRRVYDINGSVRDINVYLNGKSLKIRNFKNYVELYLKSLEKKRQLDNGEDGAAKSDIPTILYERINNRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYITDQIVKKISEILKKKKKK--SVKSFQIKNNMFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIMKTDLATRMFEIADANEENAL-KKSDGTRKSRITNYPKLEDANKAGTKEGYKCTLVLTEGDSALSLAVAGLAVVGRDYYGCYPLRGKMLNVREASADQILKNAEIQAIKKIMGLQHRKKYEDT---KSLRYGHLMIMTDQDHDGSHIKGLIINFLESSFPGLLDIQGFLLEFITPIIKVSITKPTKNTIAFYNMPDYEKWREEESHKFTWKQKYYKGLGTSLAQEVREYFSNLDRHLKIFHSLQGNDKDYIDLAFSKKKADDRKEWLRQYEPG------------TVLDPTLKEIPISDFINKELILFSLADNIRSIPNVLDGFKPGQRKVLYGCFKKNLKSELKVAQLAPYVSECTAYHHGEQSLAQTIIGLAQNFVGSNNIYLLLPNGAFGTRATGGKDAAAARYIYTELNKLTRKIFHPADDPLYKYIQEDEKTVEPEWYLPILPMILVNGAEGIGTGWSTYIPPFNPLEIIKNIRHLMNDEELEQMHPWFRGWTGTIEEIEPLRYRMYGRIEQIGDNVLEITELPARTWTSTIKEYLLLGLS-GNDKIKPWIKDMEEQHDDN-IKFIITLS--PEEMAKTRKIGFYERFKLISPISLMNMVAFDPHGKIKKYNSVNEILSEFYYVRLEYYQKRKDHMSERLQWEVEKYSFQVKFIKMIIEKELTVTNKPRNAIIQELENLGFPRFNKEGKPYYGSPNDEIAEQINDVKGATSDEEDEESSHEDTENVINGPEELYG------TYEYLLGMRIWSLTKERYQKLLKQKQEKETELENLLKLSAKDIWNTDLKAFEVGYQEFLQRDAEARGGNVPNKGSKTKGKG----------------KRKLVDDEDYDPSKKNKKSTARKGK-----------------KIKLEDKNFERILLEQKLV-------TKSKAPTKIKKEKTPSVSETKTEEEENAPSSTSSSSIFDIKKEDK-----DEGELSKISNKFKKISTIFDKMGSTSATSKEN----------------TPEQDDVATKKNQ------TTAKKTAVKPKLAKKPVRKQQKVVELSGESDLEILDSYTDREDSNKDEDDAIPQRSRRQRSSRAASVPKKSYVETLELSDDSFIEDD--------------------------------------EEENQGSD-----------------------------------------------------VSFNEED--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: :* . *** :****** ***:****** : *:**:. . : :::::****:************** ** .*. * : : : :.: *:*:***: *: :::*:* :***:*******:***********************.* :*** : : : *.* :** ::. :. * .** :**.***::* *. **:**:.:* **.**: .* :.:.* :**: * :..*:.*:::::*. . : * . .:::* * **:*. *: .***:******** ** **:::.*::: :: :::***:* :*. *::*::::* *.:****:* *****::* : *.*** * :. :::: .:. :: .. : : : *. . : .:*.. ***:***.** :.. :***:******* :***:**.*:*** ** :*****:******. .*: :****: : **:***::*.* *:****::*******:********:***:. .:* ** ** ******:*.: .: : ::**.:*::::*:. :: :: ********* ::*.:*** ::.** *: *. * :*****: :.** ** :. : :. **** **:*** :** ****.::**:*******:: ***:* * *:*****: *:* ::***** :* **:.*******:**: ** * * **** ****.*:.***:* :. *:* :: . ** : :* : :** **:**:**:*:**********: :. :: *:::*:*::::. : * * ::.: * :: : :* *.: :. . :**:*** .**. ** :* : *.:* *.: .* * *. ::*::.:: : .:. *::. *** :.:: .* ** . :::: :. :** ::: :* .** *:: : * : : . *.:** : :: : *: :: : . * : *: . * : * :: : . . . . .* ::*:*.* :* **:*: ::* : :: * *:: * : :.. :* ** .: : . :: .: * * ::: . * * * * . . .: : . . . . .* . . : * : .. . . . . . : .: : . . . . : . . . . . . : .. *: :. :. ", "identical_positions": 454, "similar_positions": 426, "identity": "27.17%" }, { "cls_id": "homologset.agr.SGD:S000005034", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62159-1", "uniprot_id": "RHOC_MOUSE", "id": "Q62159-1", "name": "Rho-related GTP-binding protein RhoC", "aln": "--------MAAIR------KKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEG-VREVFEMATRAGLQVR--------------------------KNKRR----RGCPIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QUI0-1", "uniprot_id": "RHOA_MOUSE", "id": "Q9QUI0-1", "name": "Transforming protein RhoA", "aln": "--------MAAIR------KKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDG-VREVFEMATRAALQAR--------------------------RGKKK----SGCLIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62746-1", "uniprot_id": "RHOB_MOUSE", "id": "P62746-1", "name": "Rho-related GTP-binding protein RhoB", "aln": "--------MAAIR------KKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEG-VREVFETATRAALQKR--------------------------YGSQNGCI-NCCKVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06781-1", "uniprot_id": "RHO2_YEAST", "id": "P06781-1", "name": "GTP-binding protein RHO2", "aln": "------MSEKAVR------RKLVIIGDGACGKTSLLYVFTLGKFPEQYHPTVFENYVTDCRVDGIKVSLTLWDTAGQEEYERLRPFSYSKADIILIGFAVDNFESLINARTKWADEALRYCPDAPIVLVGLKKDLRQEAHFK---ENATDEMVPIEDAKQVARAIGAKKYMECSALTGEG-VDDVFEVATRTSLLMK--------------------------KEPGA----NCCIIL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9HBH0-1", "uniprot_id": "RHOF_HUMAN", "id": "Q9HBH0-1", "name": "Rho-related GTP-binding protein RhoF", "aln": "MDAPGALAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFREN-VEDVFREAAKVALSAL--------------------------KKAQRQKKRRLCLLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0L6G2-1", "uniprot_id": "A0ABK0L6G2_RAT", "id": "A0ABK0L6G2-1", "name": "", "aln": "----MRGRSGTARGSCGGEESRPLWREYSSSPASLLRPLLSACRNSEAAAGRLRRRIIDVLEDGGDSNCRACPRWGSPYYDNVRPLCYSDSDAVLLCFDISRPETMDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSETSIHSIFRTASMVCLNKPSPVPPKSPVRSLSKRLLHLPSRSELITSTFKKEKAKSCSIM", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : ... :.** . . :.. . .. . *. *:.:**:.* .:. :*: : : : . ** * :* . ::*:. *.*** : : :. . : * *:* ** : : .:*. *: . * * ::", "identical_positions": 26, "similar_positions": 56, "identity": "10.92%" }, { "cls_id": "homologset.agr.SGD:S000005036", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80UY1-1", "uniprot_id": "CARME_MOUSE", "id": "Q80UY1-1", "name": "Protein-L-histidine N-pros-methyltransferase CARNMT1", "aln": "MQRRQRAPPASQPAQD-----GGRSEDVEVQFSAGRLGSAAP----AGPPARGTAEDEERLEREHFWKVINAFRYYGTSMHERVN-RTERQFRSLPENQQKLLPQFPLHLDKIRKCIDHNQEILLTIVNDCIHMFENKEYGEDAN-GKIMPASTF-DMD-----------------KLKSTLKQFVRDWSETGKAERDACYKPIIKEIIKNFPKERWDPSKVNILVPGAGLGRLAWEVAMLGYACQGNEWSFFMLFSSNFVLNRCSEINKYKLYPWIHQFSNNRRSADQIRPILFPDVDPHSLPPGS-NFSMTAGDFQEIYS-----------------------ECNAWDCIATCFFIDTAHNVIDYIDTIWRILKPGGIWINLGPLLYHFENLANELSIELSYEDIKNVVLQYGFQLEVEKESVLSTYTVNDLSMMKYYYECVLFVVRKPQ------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N4J0-1", "uniprot_id": "CARME_HUMAN", "id": "Q8N4J0-1", "name": "Protein-L-histidine N-pros-methyltransferase CARNMT1", "aln": "MQRRRRPPPPTSRLPEGCGGGGGGSEEVEVQFSAGRWGSAAAVSAAAAAATRSTEEEEERLEREHFWKIINAFRYYGTSMHERVN-RTERQFRSLPANQQKLLPQFLLHLDKIRKCIDHNQEILLTIVNDCIHMFENKEYGEDGN-GKIMPASTF-DMD-----------------KLKSTLKQFVRDWSETGKAERDACYQPIIKEILKNFPKERWDPSKVNILVPGAGLGRLAWEIAMLGYACQGNEWSFFMLFSSNFVLNRCSEINKYKLYPWIHQFSNNRRSADQIRPIFFPDVDPHSLPPGS-NFSMTAGDFQEIYS-----------------------ECNTWDCIATCFFIDTAHNVIDYIDTIWKILKPGGIWINLGPLLYHFENLANELSIELSYEDIKNVVLQYGFKVEVEKESVLSTYTVNDLSMMKYYYECVLFVVRKPQ------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BJ21-1", "uniprot_id": "A0A8M2BJ21_DANRE", "id": "A0A8M2BJ21-1", "name": "Carnosine N-methyltransferase", "aln": "MANSSSETVAAS------------KPEVFHNYRD---------------RNRCSPEEETRLEKQHFWNVINAFKYYRTHVHERVN-RAERQFRCLPDHHQQLLTNFLPHLNKLRYCIDQNQEVLQAVVHNCLHMFENMEYGQDVDPRKVRPSSTF-DMD-----------------KLKSTIKQFVRDWSEAGKAERDSCYKPIIDEIQRLFPPDQCDVSQVRVLVPGAGLGRLAWEIAHLGYSCQGNEWSFFMLFSSNFVLNRCDKENALTLYPWIHQFSNNKASSDQTRPVSFPDVNPQSLPEDS-DFSMVAGDFQEVYN-----------------------DPEMWDCVATCFFIDTAHNVLDYIETIWNILKPGGVWLNLGPLLYHYENMANELSIELSYEDIKAVAMKYGFVLELERESVPSTYTENDRSMLKYLYDSVFFIVRKPAKQLINGDKALKDSQTEDSLHTKNST-----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7X6-2", "uniprot_id": "CARME_DROME", "id": "Q9I7X6-2", "name": "Carnosine N-methyltransferase unmet", "aln": "MSSMDCATFPMH-------------PKMDEQLAR----------------TFVINEEE---EEKHIQKVQNAFLYYGPYACQRLK-RSMDYLNSLSGEDQIMLAKYRGHLECVRTCIDRNQAVIREILRGRVLYPTDEATGDPSEFDEPPPNVRHGDMDQIDIPFDEADVEPLKILKAQSTLKLIARDWSTEGALEREQSYKPIIDSIVAYFKHSDFELKDIKILVPGAGLGRLTYELACLGYSCEGNEFSYFMLIASNFVLNLCDNENKYVLYPWVHQYVNNLRREDQVAPVRFPDVCPLKNPPKG-HFEIAAGDFLEVYK-----------------------TPNAYNCVATCFFIDCANNVIDFIRTIYKILVPGGIWVNLGPLLYHFSDVSGQNSIEPAFEDLCIIMESVGFVIEKSRTGIRTKYAQNPSSMKQSEYQSLFWVCRKPDLFEEQRGKRKASREPHDLIVREDSEEEGEQQPERNETEEKQQLKPLATANCETEIKEQPS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53934-1", "uniprot_id": "CARME_YEAST", "id": "P53934-1", "name": "Carnosine N-methyltransferase", "aln": "---------------------------------------------------MDENEFDNQRENKAVARVIISFLKYEEYALKEIYNLRVKKWASISDRQKDMVPNYTKYLANLKAAIIENGKFFRSVAEYALQSIS-FEPGEIVQPNDLDMSKTC------------------------SLLTQVYREWSAEAISERNCLNSRLVPFLKTLSPP------KADILIPGCGTGRLLVDLSRMGYNCEGNEFSYHMLLVSQYMLNAGLLQNQIIIYPFIHCFSHWKKIEDQLSPIKVPDIEAWSSNKGMGSMSICAGSFVDCYGRNQGTKISSHYTFSRRMQLSRAKAENSKDVVVTNFFIDTGSNILDYLDTIGHVLKPGGIWCNFGPLLYHFENDHG-------VETTYEVNPYSGFQDKINDYTPLMGLELSSDDIISIATNHLDFELIRRESGILCGYGRYAGPESCAMPGYMCHYWILKSNPTNES------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : *.: . .: :* * :.: .:. ..: ::.:: :* :: .* .* .: : . : *: : . * :. . *:** . **: . :: : . :*:**.* *** ::: :** *:***:*:.**: *:::** * :**::* : : ** *: .**: . . :.: **.* : * : : :.* **** . *::*:: ** .:* ***:* *:******:.: . * : ** : . . .: . : : : : ", "identical_positions": 70, "similar_positions": 103, "identity": "13.65%" }, { "cls_id": "homologset.agr.SGD:S000005037", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61020-1", "uniprot_id": "RAB5B_HUMAN", "id": "P61020-1", "name": "Ras-related protein Rab-5B", "aln": "---------MTSRS-TARPNGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLAN------KRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLPKSEPQNLGGAAGRSR------GVDLHEQSQQNKSQCCSN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61021-1", "uniprot_id": "RAB5B_MOUSE", "id": "P61021-1", "name": "Ras-related protein Rab-5B", "aln": "---------MTSRS-TARPNGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLAN------KRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLPKSEPQNLGGAAGRSR------GVDLHEQSQQNKSQCCSN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1L1J8-1", "uniprot_id": "A1L1J8_RAT", "id": "A1L1J8-1", "name": "small monomeric GTPase", "aln": "---------MTSRS-TARPNGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLAN------KRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLPKSEPQNPGGAAGRSR------GVDLHEQAQQNKSQCCSN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQD1-1", "uniprot_id": "RAB5A_MOUSE", "id": "Q9CQD1-1", "name": "Ras-related protein Rab-5A", "aln": "---------MANRG-ATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKADLAN------KRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPKNEPQNPGANSARGR------GVDLTEPAQPARSQCCSN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RC99-1", "uniprot_id": "RAB5A_RAT", "id": "M0RC99-1", "name": "Ras-related protein Rab-5A", "aln": "---------MANRG-ATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFSRAKNWVKELQRQASPNIVIALSGNKADLAN------KRAVDFQEAQSYADDNSLLFMETSAKTPMNVNEIFMAIAKKLPKNEPQNPGANSARGR------GVDLTEPAQPARSQCCSN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20339-1", "uniprot_id": "RAB5A_HUMAN", "id": "P20339-1", "name": "Ras-related protein Rab-5A", "aln": "---------MASRG-ATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKADLAN------KRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPKNEPQNPGANSARGR------GVDLTEPTQPTRNQCCSN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35278-1", "uniprot_id": "RAB5C_MOUSE", "id": "P35278-1", "name": "Ras-related protein Rab-5C", "aln": "---------MAGRGGAARPNGPAAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLAS------KRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLPKNEPQNAAGAPGRTR------GVDLQESNPASRSQCCSN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0BNK1-1", "uniprot_id": "B0BNK1_RAT", "id": "B0BNK1-1", "name": "small monomeric GTPase", "aln": "---------MAGRGGAARPNGPAAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLAS------KRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLPKNEPQNAAGAPGRNR------GVDLQESNPASRSQCCSN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51148-1", "uniprot_id": "RAB5C_HUMAN", "id": "P51148-1", "name": "Ras-related protein Rab-5C", "aln": "---------MAGRGGAARPNGPAAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLAS------KRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLPKNEPQNATGAPGRNR------GVDLQENNPASRSQCCSN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TXV7-1", "uniprot_id": "A0AB32TXV7_DANRE", "id": "A0AB32TXV7-1", "name": "small monomeric GTPase", "aln": "---------MSTRG-TGRANGNLPQTKICQFKLVLLGDMAVGKSSLVLRFVKGQFDEFQETTIGAAFLAQSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVFDITKPETFERAKAWVKELQRQASPNIVIALAGNKADLAD------KRLVEYEEAQTYAEDTGLLFMETSAKTAMNVNELFLAIAKKMPKTDTQNP-MHAVRHR------GVNLQDPDAQSTRSCCGN--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3I2-1", "uniprot_id": "RAB5_DROME", "id": "Q9V3I2-1", "name": "Ras-related protein Rab5", "aln": "MATTPRSGGASGTGTAQRPNG-TSQNKSCQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTICIEDTVVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDIQNQDSFQRAKTWVKELHKQASPNIVIALAGNKADLSN------IRVVEFDEAKQYAEENGLLFMETSAKTGMNVNDIFLAIAKKLPKNDGANNQGTSIRPT------GTETNRP----TNNCCK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36019-1", "uniprot_id": "YPT53_YEAST", "id": "P36019-1", "name": "GTP-binding protein YPT53", "aln": "------------------MDKHTAAIPTLTIKVVLLGESAVGKSSIVLRFVSDDFKESKEPTIGAAFLTKRITRDGKVIKFEIWDTAGQERFAPLAPMYYRNAQAALVVFDVTNEGSFYKAQNWVEELHEKVGHDIVIALVGNKMDLLNNDDENENRAMKAPAVQNLCERENLLYFEASAKTGENIYQIFQTLGEKVPCPE-QNTRQSSTHDRTITDNQRIDLESTTVESTRETGGCNC", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*:****: ******:*****..:*.* :*.*******:: : :...:************: .*******.****:**:*: : :* :*: **:**:.:.. .***** *** ** . * :. .: .: .**::*:**** *: ::* ::.:*:* : * . : : . ", "identical_positions": 81, "similar_positions": 60, "identity": "33.89%" }, { "cls_id": "homologset.agr.SGD:S000005040", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62081-1", "uniprot_id": "RS7_HUMAN", "id": "P62081-1", "name": "Small ribosomal subunit protein eS7", "aln": "MFSSSAKIVKPNGEKPDEFESGISQALLELEMNS-DLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDVNFEFPEFQL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62082-1", "uniprot_id": "RS7_MOUSE", "id": "P62082-1", "name": "Small ribosomal subunit protein eS7", "aln": "MFSSSAKIVKPNGEKPDEFESGISQALLELEMNS-DLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDVNFEFPEFQL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62083-1", "uniprot_id": "RS7_RAT", "id": "P62083-1", "name": "Small ribosomal subunit protein eS7", "aln": "MFSSSAKIVKPNGEKPDEFESGISQALLELEMNS-DLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDVNFEFPEFQL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62084-1", "uniprot_id": "RS7_DANRE", "id": "P62084-1", "name": "Small ribosomal subunit protein eS7", "aln": "MFSTSAKIVKPNGEKPDEFESGISQALLELEMNS-DLKAQLRELHITAAKEIEVGGSRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTNVHDAILEDLVFPSEIVGKRIRVKLDSSRLIKVHLDKAQQNNVEHKVETFAGVYKKLTGKDVIFEFPEFQL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VA91-1", "uniprot_id": "RS7_DROME", "id": "Q9VA91-1", "name": "Small ribosomal subunit protein eS7", "aln": "-MAIGSKIIKPGGSDPDDFEKSIAQALVELEANS-DLKPYLRDLHITRAREIEFG-SKKAVIIYVPIPQQKVFQKIQIILVRELEKKFSGKHVVVIAERKILPKPTRKARNPLKQKRPRSRTLTAVYDAILEDLVFPAEIVGKRIRVKLDGSQLVKVHLDKNQQTTIEHKVDTFTSVYKKLTGRDVTFEFPDNYLNV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48164-1", "uniprot_id": "RS7B_YEAST", "id": "P48164-1", "name": "Small ribosomal subunit protein eS7B", "aln": "MSSVQSKILS---QAPSELELQVAKTFIDLESSSPELKADLRPLQIKSIREIDVTGGKKALVLFVPVPALSAYHKVQTKLTRELEKKFPDRHVIFLAERRILPKPSRTSR--QVQKRPRSRTLTAVHDKVLEDMVFPTEIVGKRVRYLVGGNKIQKVLLDSKDVQQIDYKLESFQAVYNKLTGKQIVFEIPSQTN--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :**:. . *.::* :::::::** .* :**. ** *:*. :**:. .:**::::**:* . ::*:* *.*******..:**:.:*:*:*****:*.:* ********** *:* :***:***:******:* :...:: ** **. : :::*:::* .**:****::: **:*. ", "identical_positions": 81, "similar_positions": 72, "identity": "41.12%" }, { "cls_id": "homologset.agr.SGD:S000005041", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VEK6-1", "uniprot_id": "ING3_MOUSE", "id": "Q8VEK6-1", "name": "Inhibitor of growth protein 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQ--VQNAMDQLEQRVSEFFMNAKKN----KPEWREEQMASIKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDAPSQP------------------------VNNHHAHS------------------------------------HTPVEKRK-----------------------YNPTSHHAAADHIPEKKFKSEALLSTLTSDASKENTLG---------------CRNNNSTASC---------------NNAYNVNSSQ-----------------------------------PLASYNIGSLSSGAGAG-AITMAAAQAVQATAQMKEGRRTSSLKASYEAFKNND------FQLGKEFSIPRETAGYSSSSALMTTLTQNASSSATDSRSGRKSKNNT----------------------------KSSSQQ----------------------SSSSSSSSSSSSLSLCS-------------SSSTVVQEVS----------------------------------QQATVVPES-----------DSNSQVDWTYDPNEPRYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAP-----KGKWFCPQCTAAMKRRGSRHK-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q498T3-1", "uniprot_id": "ING3_RAT", "id": "Q498T3-1", "name": "Inhibitor of growth protein 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQ--VQNAMDQLEQRVSEFFMNAKKN----KPEWREEQMASIKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDAPSQP------------------------VNNHHAHS------------------------------------HTPVEKRK-----------------------YNPTSHHTATDHIPEKKFKSEALLSTLTSDASKENTLG---------------CRNNNSTASC---------------NNAYNVNSSQ-----------------------------------PLASYNIGSLSSGAGAG-AITMAAAQAVQATAQMKEGRRTSSLKASYEAFKNND------FQLGKEFSMPRETAGYSSSSALMTTLTQNASSSAADSRSGRKSKNNT----------------------------KSSSQQ----------------------SSSSSSSSSSSSLSLCS-------------SSSTVVQEVS----------------------------------QQTTVVPES-----------DSNSQVDWTYDPNEPRYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAP-----KGKWFCPQCTAAMKRRGSRHK-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NXR8-1", "uniprot_id": "ING3_HUMAN", "id": "Q9NXR8-1", "name": "Inhibitor of growth protein 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQ--VQNAMDQLEQRVSEFFMNAKKN----KPEWREEQMASIKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDTPSQP------------------------VNNHHAHS------------------------------------HTPVEKRK-----------------------YNPTSHHTTTDHIPEKKFKSEALLSTLTSDASKENTLG---------------CRNNNSTASS---------------NNAYNVNSSQ-----------------------------------PLGSYNIGSLSSGTGAG-AITMAAAQAVQATAQMKEGRRTSSLKASYEAFKNND------FQLGKEFSMARETVGYSSSSALMTTLTQNASSSAADSRSGRKSKNNN----------------------------KSSSQQ----------------------SSSSSSSSS---LSSCS-------------SSSTVVQEIS----------------------------------QQTTVVPES-----------DSNSQVDWTYDPNEPRYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAP-----KGKWYCPQCTAAMKRRGSRHK-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWS0-1", "uniprot_id": "ING3_DROME", "id": "Q9VWS0-1", "name": "Inhibitor of growth protein 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLYLEDYLEMIEHLPQELRDRFTEMRELDLA--VQNNMDSLDKKAHMFFKQCKRDE--LQHESMDTEFHSLRGEYFKVMEDADEKVAIATQIHELVERYLRRLDSELFKFKCELEADNNGITEILERRSLELDGNSTAATALLLSMNQKENRYYGASSANTMVNSSTGHATGAATGSSGIALVSGAAGTGGALSSISTAQLGSSQRHRKLEKRRETICTVPVQEKRANLNHSLPVVGSGSTTAAAASSSSATTAAAAASLASATTAQTHVSNHIGSIAATHLTLPVAMGVAGGSSSLASSSLATGTGSLVRQLPTNLTHTVLSTSGGATAAAAAGGNSTSVVAAGTAHGHAHVSGHSAAGATVTYNLQQLGGGAAASSAIAAAASQAIVATQQMQQGRRTASLKASYEAIHGTAGTTTDFWTQAGQGGLQQSTAGSVTVAAGTALATGAAGGSSTGSHHSHHSQSHHGGHGHGHGHGHGHGHGHGHHSSSGHGGGHSSHHQEKKQKKKLTTALTLPTVQPTAGSSSGNSIGSSSSISLESVNKLTTSAALAAASATTTYMSVGGQALLAMTPGGGGGGNLAESSAEGVPAGMIAMNLPTTTVTPGSSLTIGENGLVVEQTNEGEWSYDPNEPRYCTCNQVSYGDMVACDNDACPYEWFHYPCVGITQPP-----KGKWYCPKCTASMRRRGNRKN-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8J8YN55-1", "uniprot_id": "A0A8J8YN55_RAT", "id": "A0A8J8YN55-1", "name": "Inhibitor of growth protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQR--TEDLKAEIDKLATEYMSSAR----SLSSEEKLALLRQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKRKGRTQ-----------------------------------------------------------------------------------------------------------------KEKKAARARSKGKNSDEEAP-----------------------------------------------------------------------------------------------------------------KAAQKKLKLVRTSPEYGMPSVTFGS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKP-----RGKWFCPRCSQERKKK----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C0D7-1", "uniprot_id": "ING4_MOUSE", "id": "Q8C0D7-1", "name": "Inhibitor of growth protein 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQR--TEDLKAEIDKLATEYMSSAR----SLSSEEKLALLRQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQ-----------------------------------------------------------------------------------------------------------------KEKKAARARSKGKNSDEEAP-----------------------------------------------------------------------------------------------------------------KAAQKKLKLVRTSPEYGMPSVTFGS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKP-----RGKWFCPRCSQERKKK----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UNL4-1", "uniprot_id": "ING4_HUMAN", "id": "Q9UNL4-1", "name": "Inhibitor of growth protein 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQR--TEDLKAEIDKLATEYMSSAR----SLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQ-----------------------------------------------------------------------------------------------------------------KEKKAARARSKGKNSDEEAP-----------------------------------------------------------------------------------------------------------------KTAQKKLKLVRTSPEYGMPSVTFGS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKP-----RGKWFCPRCSQERKKK----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8WYH8-1", "uniprot_id": "ING5_HUMAN", "id": "Q8WYH8-1", "name": "Inhibitor of growth protein 5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATAMYLEHYLDSIENLPCELQRNFQLMRELDQR--TEDKKAEIDILAAEYISTVK----TLSPDQRVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDK-MEGSDFESSGGRGLKKGRGQ-----------------------------------------------------------------------------------------------------------------KEKRGSRGRGR-RTSEEDTP-----------------------------------------------------------------------------------------------------------------KKKKHK-----GGSEF---TDTILS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKP-----KGKWFCPRCVQEKRKKK---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D8Y8-1", "uniprot_id": "ING5_MOUSE", "id": "Q9D8Y8-1", "name": "Inhibitor of growth protein 5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATAMYLEHYLDSIENLPCELQRNFQLMRELDQR--TEDKKAEIDILAAEYISTVK----TLSSAQRVEHLQKIQSAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDR-MDGSDFESTGARSLKKGRSQ-----------------------------------------------------------------------------------------------------------------KEKRSSRGRGR-RTSEEDTP-----------------------------------------------------------------------------------------------------------------KKKKHK-----SGSEF---TDSILS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKP-----KGKWFCPRCVQEKRKKK---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GKJ6-1", "uniprot_id": "A0A8I6GKJ6_RAT", "id": "A0A8I6GKJ6-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATAMYLEHYLDSIENLPCELQRNFQLMRELDQR--TEDKKAEIDILAAEYISTVK----TLSSAQRVEHLQKIQSAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDR-MDGSDFESTGSRSLKKGRSQ-----------------------------------------------------------------------------------------------------------------KEKRSSRGRGR-RTSEEDTP-----------------------------------------------------------------------------------------------------------------KKKKHK-----SGSEF---NDSILS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDVLSPMCSGEEEEEVAKRPLSGLKSELIYSSLMLQYYLSF---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VJY8-1", "uniprot_id": "ING5_DROME", "id": "Q9VJY8-1", "name": "Inhibitor of growth protein 5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSAIYLENYLDGLESLPTELERNFKLMRKLDDR--AQTAMKSIDSHAKDFMRKLGEN-GAMSEDERRERQEDIKALFGKAKEYSDDKVQLAIQTYELVDKQIRRLDNDLARFEGEIQEK--ASSTRAKSEEVVAKKGRKKT----------------------------------------------------------------------------------------------------------------KDSKTTGKKKKSASSDEETGRGNN-------------------------------------------------------------------------------------------QSNANSSVNSSSNAGQGSKKKKSKVNQEKETRKGGAQKKTVEVDDSEKESC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HTAATHPSDVMDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVGLTTKP-----KGKWFCPKCTQDRKKK----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0ABZ3NNN7-1", "uniprot_id": "A0ABZ3NNN7_RAT", "id": "A0ABZ3NNN7-1", "name": "Inhibitor of growth protein", "aln": "MRGGNRHLKTEGRGRTAYLRGRPRYSGSLAATGAQPWPRGARREVAAHARSRARCTLGRFSSLRPHSASSAQGPLAAVLEAREGGAGSARWRQVEIGGLGGALSSGGRVPAAPGCRAEERRSWLLHVWLLDAEAAAAAAARSSSGGRMLGQQQQ--LYSSAALLTGERSRLLTCYVQDYLECVESLPHDMQRNVSVLRELDN--KYQETLKEIDDVYEKYKKEDD-------SNQKKRLQQHLQRALINSQELGDEKIQIVTQMLELVENRARQMELHSQCFQDPAES--------ERASDKSKMDSS-QPER---------------------------------------------------------------------------------------------------------SSRRPRRQRTSESRDLCHMTNGIDDC----------------------------------------------------------------------------------------------------------------DDQPPKEKKSKSAKKKKRSKAKQER-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EASPVEFAIDPNEPTYCLCNQVSYGEMIGCDNEQCPIEWFHFSCVSLTYKP-----KGKWYCPKCRGDSEKTMDKSTEKTRKERRAR-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ESK4-1", "uniprot_id": "ING2_MOUSE", "id": "Q9ESK4-1", "name": "Inhibitor of growth protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MLGQQQQQQLYSSAALLTGERSRLLSCYVQDYLECVESLPHDMQRNVSVLRELDN--KYQETLKEIDDVYEKYKKEDD-------SNQKKRLQQHLQRALINSQELGDEKIQIVTQMLELVENRARQMELHSQCFQDPAES--------ERASDKSKMDSS-QPER---------------------------------------------------------------------------------------------------------SSRRPRRQRTSESRDLCHMTNGIDDC----------------------------------------------------------------------------------------------------------------DDQPPKEKRSKSAKKKKRSKAKQER-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EASPVEFAIDPNEPTYCLCNQVSYGEMIGCDNEQCPIEWFHFSCVSLTYKP-----KGKWYCPKCRGDNEKTMDKSTEKTKKERRAR-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H160-1", "uniprot_id": "ING2_HUMAN", "id": "Q9H160-1", "name": "Inhibitor of growth protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MLGQQQQQ-LYSSAALLTGERSRLLTCYVQDYLECVESLPHDMQRNVSVLRELDN--KYQETLKEIDDVYEKYKKEDD-------LNQKKRLQQLLQRALINSQELGDEKIQIVTQMLELVENRARQMELHSQCFQDPAES--------ERASDKAKMDSS-QPER---------------------------------------------------------------------------------------------------------SSRRPRRQRTSESRDLCHMANGIEDC----------------------------------------------------------------------------------------------------------------DDQPPKEKKSKSAKKKKRSKAKQER-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EASPVEFAIDPNEPTYCLCNQVSYGEMIGCDNEQCPIEWFHFSCVSLTYKP-----KGKWYCPKCRGDNEKTMDKSTEKTKKDRRSR-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QXV3-1", "uniprot_id": "ING1_MOUSE", "id": "Q9QXV3-1", "name": "Inhibitor of growth protein 1", "aln": "-----------MLSPAN--------------------------------------------------GEQIHLVNY----VEDYLDS-----------------------------------------------------IESLPFDLQRNVSLMR--------------------------------EIDAK------------YQEILKELDDYYEKFKRETD-------GTQKRRVLHCIQRALIRSQELGDEKIQIVSQMVELVENRSRQVDSHVELFEAHQDISDGTGGSGKAGQDKSKSEAITQADKP--------------------------------------------------------------------------------------------------------NNKRSRRQRNNENRENASNNHDHDDI----------------------------------------------------------------------------------------------------------------TSGTPKEKKAKTSKKKKRSKAKAER-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKP-----KGKWYCPKCRGESEKTMDKALEKSKKERAYNR------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UK53-1", "uniprot_id": "ING1_HUMAN", "id": "Q9UK53-1", "name": "Inhibitor of growth protein 1", "aln": "----MSFVECPYHSPAERLVAEADEGGPSAITGMGLCFR---------------CLLFSFSGRSGVEGGRVDLNVFGSLGLQPWIGSSRCWGGPCSSALRCGWFSSWPPPSKSAIPIGGGSRGAGRVSRWPPPHWLEAWRVSPLPLSPLSPATFGRGFIAVAVIPGLWARGRGCSSDRLPRPAGPARRQFQAASLLTRGWGRAWPWKQILKELDECYERFSRETD-------GAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKP--------------------------------------------------------------------------------------------------------NSKRSRRQRNNENRENASSNHDHDDG----------------------------------------------------------------------------------------------------------------ASGTPKEKKAKTSKKKKRSKAKAER-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKP-----KGKWYCPKCRGENEKTMDKALEKSKKERAYNR------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VEF5-1", "uniprot_id": "Q9VEF5_DROME", "id": "Q9VEF5-1", "name": "Inhibitor of growth protein", "aln": "-MINPIASESEAINSATYVDNYIDSVENLPDDVQRQLSR---------IRDIDVQYRGLIRDVDHYYDLYLSLQNSADAGRRSRSISRMHQSLIQAQELGDEKMQIVNHMQEIIDGKLRQLDTDQQNLDLKEDRDRYALLDDGTPSKLQRLQSPMREQGNQAGTGNGGLNGNGLLSAKDLYALGGYAGGVVPGSNAMTSGNGG-GSTPNSERSSHVSNGGNSGSN-------GNASGGGGGELQRTGSKRSRRRNESVVNNGSSLEMGGNESNSANEASGSGGGSGERKSSLG---GASGAGQGRKASLQSASG--------------------------------------------------------------------------------------------------------SLASGSAATSSGAAGGGGASGAGVVG----------------------------------------------------------------------------------------------------------------GNNSGKKKKRKVRGSGASNANASTR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EETPPPETIDPDEPTYCVCNQISFGEMILCDNDLCPIEWFHFSCVSLVLKP-----KGKWFCPNCRGERPNVMKPKAQFLKELERYNKEKEEKT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50947-1", "uniprot_id": "PHO23_YEAST", "id": "P50947-1", "name": "Transcriptional regulatory protein PHO23", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSPANLFPGLNDITDVLEEFPLATSRYLTLLHEIDAK--CVHSMPNLNERIDKFLKKDFN----KDHQTQVRLLNNINKIYEELMPSLEEKMHVSSIMLDNLDRLTSRLELAYEVAIKNTEIPRGLRLGVDNHPAMHLHHELMEKIES-------------------------------------------------------------------------------------------------------KSNSKSSQALKSESRREAMAANRRQGEHYS------------------------------------------------------------------------------------------ASTHQQDDSKNDANYGGSRHESQDHTGNNTNSRKRANAANTNNADPETKKRKRRVATTAVSPSTISTATAVNNGRIGTSTASRGVSSVGNS----------------------------------------------------------------------------------------------------------------------------------------------------------------NNSRISRPKTNDYGEPLYCYCNQVAYGEMVGCDGADCELEWFHLPCIGLETLP-----KGKWYCDDCKKKL-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. . ::.: : . : . . * .** ** *:*:::*:*: **. :.: ", "identical_positions": 11, "similar_positions": 24, "identity": "1.24%" }, { "cls_id": "homologset.agr.SGD:S000005042", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62070-1", "uniprot_id": "RRAS2_HUMAN", "id": "P62070-1", "name": "Ras-related protein R-Ras2", "aln": "MAA---------------AGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQ----------------------------------EQECPPSPEPTRKEKDKKGCHCVIF----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5BJU0-1", "uniprot_id": "Q5BJU0_RAT", "id": "Q5BJU0-1", "name": "", "aln": "MAA---------------AGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQ----------------------------------EQECPPSPEPTRKEKDKKGCHCVIF----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62071-1", "uniprot_id": "RRAS2_MOUSE", "id": "P62071-1", "name": "Ras-related protein R-Ras2", "aln": "MAA---------------AGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQ----------------------------------EQECPPSPEPTRKEKDKKGCHCVIF----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10833-1", "uniprot_id": "RRAS_MOUSE", "id": "P10833-1", "name": "Ras-related protein R-Ras", "aln": "MSSGAASGTGRGRPRGGGPGPRDPPPGETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICTVDGIPARLDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNKADLENQRQVLRSEASSFSASHHMTYFEASAKLRLNVDEAFEQLVRAVRKYQ----------------------------------EQELPPSPPSAPRKKDG-GCPCVLL----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z8L7-1", "uniprot_id": "RRAS_RAT", "id": "D3Z8L7-1", "name": "Ras-related protein R-Ras", "aln": "MSSGAASGTGRGRPRGGGPGPRDPPPGETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICTVDGIPARLDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFIEVSKLFTQILRVKDRDDFPIVLVGNKADLETQRQVLRSEASSFSASHHMTYFEASAKLRLNVDEAFEQLVRTVRKYQ----------------------------------EQELPPSPPSAPRKKDG-RCPCVLL----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04388-1", "uniprot_id": "RAS2_DROME", "id": "P04388-1", "name": "Ras-like protein 2", "aln": "------------------------MQMQTYKLVVVGGGGVGKSAITIQFIQSYFVTDYDPTIEDSYTKQCNIDDVPAKLDILDTAGQEEFSAMREQYMRSGEGFLLVFALNDHSSFDEIPKFQRQILRVKDRDEFPMLMVGNKCDLKHQQQVSLEEAQNTSRNLMIPYIECSAKLRVNVDQAFHELVRIVRKFQ----------------------------------IAERPFIEQDYKKKGKR---KCCLM----------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08646-1", "uniprot_id": "RAS1_DROME", "id": "P08646-1", "name": "Ras-like protein 1", "aln": "--------------------------MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAVNSAKSFEDIGTYREQIKRVKDAEEVPMVLVGNKCDLASW-NVNNEQAREVAKQYGIPYIETSAKTRMGVDDAFYTLVREIR-------------------------------------KDKDNKGRRGRKMNKPNRRFKCKML----------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P79737-1", "uniprot_id": "RASN_DANRE", "id": "P79737-1", "name": "GTPase NRas", "aln": "--------------------------MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADVHLYREQIKRVKDSDDVPMVLVGNICDLAR--TVDTKQAQELARSYGIEFVETSAKTRQGVEDAFYTLVREIR-------------------------------------HYRMKKLNSREDRKQGCLGVSCEVM----------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P01120-1", "uniprot_id": "RAS2_YEAST", "id": "P01120-1", "name": "Ras-like protein 2", "aln": "-------------------MPLNKSNIREYKLVVVGGGGVGKSALTIQLTQSHFVDEYDPTIEDSYRKQVVIDDEVSILDILDTAGQEEYSAMREQYMRNGEGFLLVYSITSKSSLDELMTYYQQILRVKDTDYVPIVVVGNKSDLENEKQVSYQDGLNMAKQMNAPFLETSAKQAINVEEAFYTLARLVRDEGGKYNKTLTENDNSKQTSQDTKGSGANSVPRNSGGHRKMSNAANGKNVNSSTTVVNARNASIESKTGLAGNQATNGKTQTDRTNIDNSTGQAGQANAQSANTVNNRVNNNSKAGQVSNAKQARKQQAAPGGNTSEASKSGSGGCCIIS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*****.*******:***: *.:** :********* * :*. . ***********:.***:**** *:*** *:::.. *: :: ** **** : .*::::** .** * .:. . : . :.* *** .*::** *.* :* . : . ", "identical_positions": 75, "similar_positions": 46, "identity": "21.99%" }, { "cls_id": "homologset.agr.SGD:S000005045", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BHK3-1", "uniprot_id": "S36A2_MOUSE", "id": "Q8BHK3-1", "name": "Proton-coupled amino acid transporter 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVTKSARSPQVATPLNLDL---PESAKKLQSQDPS-----------------------------------------------------------PANGSSSESS--KKTKGITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHILVRCAQRFCHRLN-KPFMDYGDTVMHGLAFSPNAWLQNHAHWGRRVVSFFLIVTQLGFCCVYIVFLADNLKQVVEA-------VNSTTISCHKNETVVLTPTMDSRLYMLSFLPVLGLLVFVRNLRVLTIFSLLANISMLVSLVIIAQY----IIQEIPDASQLP--LVASWKTYPLFFGTAIFSFESIGVVLPLENKMKDARGFP---TILSLGMSIITTLYIAIGALGYLRFGDDIKASITLNLP-NCWLYQSVKLLYVVGILCTYALQFYVPAEIIIPLAV-----------------------SQVSKRWALPVDLSIRLALVCLTCMLAILIPRLDLVLSLVGSVSSSALALIIPPLLEVVTYYGE-----GISPLTVTKDALISILGFMGFVVGTYQALDELIKSGNSPALSNSTMFIQ-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K415-1", "uniprot_id": "S36A2_RAT", "id": "Q8K415-1", "name": "Proton-coupled amino acid transporter 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVTKSAGSPQVAATVKLDLVSFPESAKKVQSQDPN-----------------------------------------------------------PVNGSSSESS--EKTKGITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHILVRCAQRFCHRLN-KPFMDYGDTVMHGLASSPNTWLQSHAHWGRHAVSFFLIVTQLGFCCVYIVFLADNLKQVVEA-------VNSTTISCHKNETVVLTPTIDSRLYMLAFLPVLGLLVFIRNLRVLTIFSLLANVSMLVSLVIIGQY----IIQGIPDPSQLP--LVASWKTYPLFFGTAIFSFESIGVVLPLENKMKDARRFP---TILSLGMSIITTLYIAIGALGYLRFGDDIKASITLNLP-NCWLYQSVKLLYVVGILCTHALQFYVPAEIIIPLAV-----------------------SQVSKRWALPVDLSIRLALVCVTCMLAILIPRLDLVLSLVGSVSSSALALIIPPLLEVTTYYGE-----GMSPLTITKDALISILGFMGFVVGTYQALDELIRSGNSLPLSNSTMFIQ-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q495M3-1", "uniprot_id": "S36A2_HUMAN", "id": "Q495M3-1", "name": "Proton-coupled amino acid transporter 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVTKSTEGPQGAVAIKLDLMSPPESAKKLENKDST-----------------------------------------------------------FLDESPSESAGLKKTKGITVFQALIHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMHILVKCAQRFCKRLN-KPFMDYGDTVMHGLEANPNAWLQNHAHWGRHIVSFFLIITQLGFCCVYIVFLADNLKQVVEA-------VNSTTNNCYSNETVILTPTMDSRLYMLSFLPFLVLLVLIRNLRILTIFSMLANISMLVSLVIIIQY----ITQEIPDPSRLP--LVASWKTYPLFFGTAIFSFESIGVVLPLENKMKNARHFP---AILSLGMSIVTSLYIGMAALGYLRFGDDIKASISLNLP-NCWLYQSVKLLYIAGILCTYALQFYVPAEIIIPFAI-----------------------SRVSTRWALPLDLSIRLVMVCLTCLLAILIPRLDLVISLVGSVSGTALALIIPPLLEVTTFYSE-----GMSPLTIFKDALISILGFVGFVVGTYQALDELLKSEDSHPFSNSTTFVR-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K4D3-1", "uniprot_id": "S36A1_MOUSE", "id": "Q8K4D3-1", "name": "Proton-coupled amino acid transporter 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTQRLRNED------YHDYSSTDVSPEESPSEGLG-----------------------------------------------------------SFS-PGSYQR-LGENSSMTWFQTLIHLLKGNIGTGLLGLPLAVKNAGLLLGPLSLLVIGIVAVHCMGILVKCAHHLCRRLN-KPFLDYGDTVMYGLECSPSTWVRNHSHWGRRIVDFFLIVTQLGFCCVYFVFLADNFKQVIEA-------ANGTTTNCNNNVTVIPTPTMDSRLYMLSFLPFLVLLSFIRNLRVLSIFSLLANISMFVSLIMIYQF----IVQRIPDPSHLP--LVAPWKTYPLFFGTAIFAFEGIGVVLPLENKMKDSQKFP---LILYLGMAIITVLYISLGSLGYLQFGANIKGSITLNLP-NCWLYQSVKLLYSIGIFFTYALQFYVAAEIIIPAIV-----------------------SRVPEHFELMVDLCVRTAMVCVTCVLAILIPRLDLVISLVGSVSSSALALIIPPLLEVVTYYGE-----GISPLTVTKDALISILGFVGFVVGTYESLCELIQPSHSDSSTNSTSAFI-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q924A5-1", "uniprot_id": "S36A1_RAT", "id": "Q924A5-1", "name": "Proton-coupled amino acid transporter 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTQRLRNED------YHDYSSTDVSPEESPSEGLG-----------------------------------------------------------SFS-PGSYQR-LGENSSMTWFQTLIHLLKGNIGTGLLGLPLAVKNAGLLLGPLSLLVIGIVAVHCMGILVKCAHHLCRRLN-KPFLDYGDTVMYGLECSPSTWIRNHSHWGRRIVDFFLVVTQLGFCCVYFVFLADNFKQVIEA-------ANGTTTNCNNNETVILTPTMDSRLYMLTFLPFLVLLSFIRNLRILSIFSLLANISMFVSLIMIYQF----IVQRIPDPSHLP--LVAPWKTYPLFFGTAIFAFEGIGVVLPLENKMKDSQKFP---LILYLGMAIITVLYISLGSLGYLQFGADIKGSITLNLP-NCWLYQSVKLLYSIGIFFTYALQFYVAAEIIIPAIV-----------------------SRVPERFELVVDLSARTAMVCVTCVLAVLIPRLDLVISLVGSVSSSALALIIPPLLEVTTYYGE-----GISPLTITKDALISILGFVGFVVGTYESLWELIQPSHSDSSTNSTSAFI-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z2H8-1", "uniprot_id": "S36A1_HUMAN", "id": "Q7Z2H8-1", "name": "Proton-coupled amino acid transporter 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTQRLRNED------YHDYSSTDVSPEESPSEGLN-----------------------------------------------------------NLSSPGSYQR-FGQSNSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLN-KSFVDYGDTVMYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEA-------ANGTTNNCHNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQF----IVQRIPDPSHLP--LVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFP---LILYLGMVIVTILYISLGCLGYLQFGANIQGSITLNLP-NCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFV-----------------------SRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTTFYSE-----GMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q811P0-1", "uniprot_id": "S36A3_MOUSE", "id": "Q811P0-1", "name": "Proton-coupled amino acid transporter 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNVPLLREV--GKCQRNMFGRSTASSKGSSNSRSS-----------------------------------------------------------SSTSPKKGPR--READALMFIQIFIHLLKSNIGTGFLGLPLAVKNAGLLVGPVSLLAIGALTVHCMDILLNCACHLTQRLQ-RSFVNYEETTMYSLETCPSPWLRTHSVWGRYVVSFLLIVTQLGFCSVYFMFLADNLQQIMEE-------AHFTSNVCQPRQSLVMTSILDTRFYMLTILPFLILLVLIQNPQVLSIFSTLATITTLSSLALIFEY----LIQ-TPHHSNLP--LVANWKTFLLFFGTAIFTFEGVGMVLPLKSQMKSPQQFP---AVLYLGMSFVIFLYICLGTLGYMKFGTDTQASITLNLP-ICWLYQSVKLMYSVGIFFTYALQFHVPAEIIVPYVV-----------------------SRVSENWALFVDLTVRTALVCLTCFSAVLIPRLDLVISLVGSVSSSALAIIIPPLLEIATFYSE-----NISCATIVKDIMISILGLLGCVLGTYQALYEMTQQT-HFYMANSTRVHI-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V8B1-1", "uniprot_id": "S36A3_RAT", "id": "Q4V8B1-1", "name": "Proton-coupled amino acid transporter 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKTPLLRED--GRCQRNTFGGSKASSKGSSSSSSN-----------------------------------------------------------NTVSSKKKPR--RKADALMFIQIFIHLLKSNIGTGFLGLPLAVKNAGLLVGPVSLLAIGALTVHCMDILLNCACHLTSRLQ-RSFVNYEETTMYSLETCPSPWLRTHSVWGRYVVSFLLIVTQLGFCSVYFMFMADNLQQIVEE-------AHFTSNVCQPRQSLVMTSILDTRFYMLTILPFLILLVLVQNPQVLSIFSTLATITTLSSLALIFEY----LIQ-IPHHSHLP--LVASWKTFLLFFGTAIFTFEGVGMVLPLKSQMKSPQQFP---AVLYLGMSFVIFLYICLGTLGYMKFGADTQASITLNLP-NCWLYQSVKLMYSVGIFFTYALQFHVPAEIIVPYVV-----------------------SRASENWALFIDLTVRAALVCLTCFSAVLIPRLDLVISLVGSVSSSALALIIPPLLEIATFYSE-----NISCTTIAKDIMISILGLLGCVLGTYQALYEMTQQS-RFPMLNSTNVHT-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q495N2-1", "uniprot_id": "S36A3_HUMAN", "id": "Q495N2-1", "name": "Proton-coupled amino acid transporter 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLLGRD--YNSELNSLDNGPQSPSESSSSITS-----------------------------------------------------------ENVHPAG-------EAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQHLSQRLQ-KTFVNYGEATMYGLETCPNTWLRAHAVWGRYTVSFLLVITQLGFCSVYFMFMADNLQQMVEK-------AHVTSNICQPREILTLTPILDIRFYMLIILPFLILLVFIQNLKVLSVFSTLANITTLGSMALIFEY----IMEGIPYPSNLP--LMANWKTFLLFFGTAIFTFEGVGMVLPLKNQMKHPQQFS---FVLYLGMSIVIILYILLGTLGYMKFGSDTQASITLNLP-NCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAI-----------------------SQVSESWALFVDLSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLEIVIFYSE-----DMSCVTIAKDIMISIVGLLGCIFGTYQALYELPQPI-SHSMANSTGVHA-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CH36-1", "uniprot_id": "S36A4_MOUSE", "id": "Q8CH36-1", "name": "Neutral amino acid uniporter 4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAPAPAETAGCEELDMDVMRPLINEQNFDGSSDEEQE-----------------------------------------------------------QTLVPIQKHYQLDGQHGISFLQTLVHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCQRFK-KSTLGYSDTVSFAMEASPWSCLQRQAAWGRQVVDFFLVITQLGFCSVYIVFLAENVKQVHEG----FLGSTPIVSNGSDLSHACERRSVDLRVYMLCFLPLIILLVFIRELKNLFVLSFLANISMAASLVIIYQY----VVRNMPDPHNLP--IVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMRESKRFP---QALNIGMAIVTVLYISLATLGYMCFRDEIKGSITLNLPQDMWLYQSVKILYSFGIFVTYSIQFYVPAEIIIPGVT-----------------------ARLHAKWKRICEFGIRSLLVSITRAGAILIPRLDIVISFVGAVSSSTLALILPPLVEILTFSKD-----HYNIWMILKNISIAFTGVVGFLLGTYVTVEEIIYPTTAVVAGTSQSPFLNVNSTCITSGL------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L655-1", "uniprot_id": "A0ABK0L655_RAT", "id": "A0ABK0L655-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCQPFMVVFNKGIYNKDMDVMRPLINEQNFDGSSDEEQE-----------------------------------------------------------QTLLPMQKHYQLDGQHGISFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCQRFK-KSTLGYSDTVSFAMEASPWSCLQRQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQVHEG----LLETTVVVSNSSDLSQVCERRSVDLRVYMLCFLPLLILLVFIRELKSLFVLSFLANISMAASLVIIYQY----VVRSMPDPHNLP--IVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMRESKRFP---QALNIGMAIVTVLYISLATLGYMCFRDEIKGSITLNLPQDMWLYQSVKILYSFGIFVTYSIQFYVPAEIIIPAVT-----------------------ARLHAKWKCICDFGIRSLLVSITCAGAVLIPRLDIVISFVGAVSSSTLALILPPLVEILTFSKD-----HYNVWMVLKNISIAFTGFVGFLLGTYVTVEEIIYPTTAVADGASQSLSLNVNSTCVSSGL------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6YBV0-1", "uniprot_id": "S36A4_HUMAN", "id": "Q6YBV0-1", "name": "Neutral amino acid uniporter 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAAATPAAAGAARREELDMDVMRPLINEQNFDGTSDEEHE-----------------------------------------------------------QELLPVQKHYQLDDQEGISFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCLRFK-KSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQVHEG----FLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFIILLVFIRELKNLFVLSFLANVSMAVSLVIIYQY----VVRNMPDPHNLP--IVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKESKRFP---QALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIFVTYSIQFYVPAEIIIPGIT-----------------------SKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVGAVSSSTLALILPPLVEILTFSKE-----HYNIWMVLKNISIAFTGVVGFLLGTYITVEEIIYPTPKVVAGTPQSPFLNLNSTCLTSGLK-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B732-1", "uniprot_id": "A0ACD6B732_DANRE", "id": "A0ACD6B732-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASADQLDMEVMTPLMEKAEGD---EEEED-----------------------------------------------------------ENVDGDEDSKHLP--QGITFTQTLLHLLKGNIGTGLLGLPLAVKNAGIVLGPVSLVLMGVVCVHCMHILVNCSHQLSERLK-RSPLGYSETVAAAMELSSSQCLRRGAHFGRHLVNFFLVLTQLGFCSVYFVFLAENIKQVMEGTHMNSTAETVLLSSNSSEASAVSSVAIDLRLYMVFLLPFIIVLTFIRDLRNMAALSAIANLCMAISLIFIFSY----ILNDLSDPRRLP--YASTWRKFPFFFGTAIFAFEGIGVVLPLENQMREPKRFP---QALNIGMGFIIVLYVTLATLGYLRFRDDIKGSITLNLPHDSWSNQLVKVLYSFGVFVSFAVQFFVPAEILLPPMC-----------------------ERVRKSWRRVADLSLRALLVCLTCVTAVLIPRLDLVISLVGAVSSSALALVFPPLVELIAFPSQ-----PPPPMLLLKDISIAALGFIGFLTGTYVTVEEIIYPDVQGQIRLHDDGNWTTPTTSTP---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q4V5R4-1", "uniprot_id": "POLYP_DROME", "id": "Q4V5R4-1", "name": "Glutamate transporter polyphemus", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPKSQDQAPNRDDPDLQTEPLTIAQSI-------------------------------------------------------------TSFYMYNPYEKRSVEVPLTNCDAFISLLKCVIGTGILAMPLAFRCSGFVMGTVMSILLMILLTYSIHLLIADMTECCRRRR-VPQVSMPEAVRIAYEEGP-KWINCFGRAAGFMTTCVLVFGQFLLCTVYLVFVSKNFKEIGDH---------------------YIER-YNERYYVLVACLLLLPLFMIRRLKYLVPLNLISNFLLYAGFALIMYY----LFNGLPNINDRE-MVTPPVEWI-EFIAIAAFSLTAVGSMLVVEAHMAHPQSYLGLFGVLNLAVLFILLSNMFFGIIGYWRFGDNVHASITLNIPQDEILSQFIKVFIASGIFLSYPLNGFVVITVMFSDYE----------------------NSEPRGRYRTLIEYVVRLLFLFLTGAVAIGVPNLAALTELEGAFSLSNLNLLCPALIDVFLNYN---VGYGRLMWKLIRDILLILIGLIFGIVGCTVALMQLIRDF---------------------QLTLNSM--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQF3-1", "uniprot_id": "Q8IQF3_DROME", "id": "Q8IQF3-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDKGG----------------------------------------------------------------------------------------FDPYENRNVAHPISDIGAFFSLLKCVVGTGVMAIPLSFNYAGIVTGIILLVSVCFMLIHGMQMLIICMIECSRRMQ-IGYATYPVAMVYSFDQGP-RFFKYISKAGRYIVDGVLAFSQFGVCVVYNVFVAATLKQLVDF---------------------YWVV-ADLRIYIAVIALCLIPPFQIRKLKYLVPFNILASILIYTGFSLMMYY----LFVDLPPITERN-ILFGRIDKIPLFFGIALFSITSVGVMLAVEATMAKPRHYLGWFGILDRAILLVIISYVTFGLMGYWRYGDETAGSISLNIPTDEVLSQVAKGFIAAAIFLTYPLAGFVIIDIIMNHFW----------------------NKNGDLPNAALKESILRACTVVLICITAIIAPNLGPLLSLVGALTISLLNLVFPALIEICLYYPP-EYNYGKLKWVLVKDIFYVIVGILILVQGTVFSIKDMISEWGGGDTTTGGPETTAEETTANMSATLTTALTAAPPDALRFRFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W056-1", "uniprot_id": "S36A_DROME", "id": "Q9W056-1", "name": "Proton-coupled amino acid transporter-like protein acs", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNDDIKT--VTVYPTTLELTTPTKSAN-------------------------------------------------------------GSNDDYDPHQHRELKNPTTNFQTFAHFLKASVGTGVLAMPSAFAHAGYVNGTLLTLIIGSLALYCLHILIKCMYILCKRQR-VPYVSFSQAMNLGLKQGP-PWLRCLAPIAVPFVDGFLAFYHFGICCVYVVFIAESIKQLVDE---------------------YLVV-WDVRIHMCIIIVPLLLIYSIKNLKLLAPFSSAANLLLLVGFGIILYY----IFEELPPLSERD-PFVA-AGKLPTFFGTVLFALEAVGVILAIEENMATPKSFVGPCGILNSGMSIVLGLYVLLGFFGYWKYGNESEGSITLNIPQSEIPAQVVKVFFAITTWISYALQGYVTAHILWDKYL----------------------AKRFKETRQTFYELIFRAIIVLLTFGCAVAIPDLSVFLSLVGSFCLSILGLIFPVLLQICVQYT---EGYGPFRIKLIINLLLLCFGIFGGVVGTYVSILDIIAVYK-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTD5-1", "uniprot_id": "Q9VTD5_DROME", "id": "Q9VTD5-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRNTRRRRLDQKLPFHQRLLGGVQNSF-------------------------------------------------------------GSPLANEARLSSKKDNGMSDLEAFINVLKCGFGTGCLAMPYAFLNSGWLVGLICTFALGFFVLYAMHILLHHINNLGVQHN-MPMISYRKAVELSIRKGP-SIFHFLSKPFGYLVDILLCAYHFGVDCVYVVFIAKSLKHLGDM---------------------YLWV-WDERLYMALIASPLILTFLIRNLKSLVPFSIISNILLLTGYCVILNY----LFRDLPEFEHLH-AIQP-LRNFPIFFGTVLFSIESVGVILSLGRSMRKPESLMGTCGVLNQGMIVVISFYAVFGFFGYWRYGENTSNSILQNMPQNDILPKLATGIFALAIFFSYALQGYVTVDIIWRNYL----------------------EPELEDRYLRTVECLLRIALVIASVLVAIQYPDFGLLLSLVGSFCLAQLGLILPGIVDICLRYE---EDYGPGKIFLIRSMLFICMGLAGGVAGTVVTLQTLYARYPVVRG-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VT04-1", "uniprot_id": "PATH_DROME", "id": "Q9VT04-1", "name": "Proton-coupled amino acid transporter-like protein pathetic", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MVNIVDSGSK-------HAPQEMEQFLP----------GEGKVMYKIQPRKSDTEQALAGN----------------------------------------------------------------------DFDPFALRDNPHPTTDNETLTHLLKASLGTGILGMPFAFMCSGLIMGIFSTIFTAFICTHCSYVLVKCGHKLYYRTR-RTKMTFAEIAEAAFQKGP-KWCRGFAPVAKFSILFGLFLTYFGTCSVYTVIVASNFEQLISY---------------------WTGTAVSLRMLICIMLVPLILIAWVPNLKYLAPVSMVANVFMGLGLGITFYY----LVQDLP-PVEER-ESVV-WSTLPQFFSITIFAMEAIGVVMPLENNMKTPQSFLGICGVLSQGMSGVTLIYMLLGFLGYLRYGSATGESITLNLPIEEWPAQTVKVLISLAVYCTFGLQFFVCLEIIWDGIK----------------------EKCK--KRPTLVNYVLRTVLVTAAVVLAVAVPTIGPFMGLIGAFCFSILGLIFPVVIELIVHWES---GFGKYNWILWKNAIITLCGIGALVFGTQAAIKDIVKAYSNNENVGE----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PEU1-1", "uniprot_id": "M9PEU1_DROME", "id": "M9PEU1-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------MSTPENLNAPAGKPPLPPRREQLTEKGQSLSLSSFGGSAGNISGSGRKQHLSGAALARHKLKMSLKRGGPPPVATSGSGVMTTSLDQQKIPTVTAGYGENEKPKGGKGGQSKFIRSDMADVPVQQAAGSTLPLVIS-----------------------RKKGDDSEDGNYNPFEHRKVEHPTSDLETFVHLLKGSLGSGILAMPMAFSHAGLWFGLVATFAVGTLCTYCVHILVKCAHILCRRRK-IPMMGFADVAEQAFLDGP-PALNRWSRFIRFMVNTFLVIDLLGCCCIYLVFVATNVEQVVRV---------------------YMETELSIRVWIMIVTAPLIFMCLVRNLKFLTPFSMIANILMFVGIVITFIY----MFSDIPAPVERP-GIVS-VTEWPLFFGTVIFALEGIGVVMSLENDMKNPSHFIGCPSVLNFGMGLVIALYTLVGFFGFLKYGPETQASITLNLPLEDKLAQSVKLMIAIAIFFTFTLQFYVPVTILWKGLE----------------------HKIRP-EKQNISEYGLRVFLVLLCGGIAVALPNLGPFISLIGAVCLSTLGMIVPATIELAVYHEDP--GYGRFNWRLWKNSGLILFGVVGFVAGTYVSIIEFHAEFSSGH--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLM3-1", "uniprot_id": "Q9VLM3_DROME", "id": "Q9VLM3-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------MEDLTPLTNLQQIPEGAPRKKKMTERQPLLLQS----DASDYEGSRGS--------AARPVRSSPP-----------DNTLVNVHSEDSLAASGSGDDEIG----------------------------------------------------------------STDKSYNPTHHRDLEHPTSNFDTLVHLLKGNIGTGILAMPDAFKNAGLYVGLFGTMIMGAICTHCMHMLVNCSHELCRRFQ-QPSLDFSEVAYCSFESGP-LGLRRYSMLARRIVTTFLFITQIGFCCVYFLFVALNIKDVMDH---------------------YYK--MPVQIYLLIMLGPMILLNLVRNLKYLTPVSLVAALLTVAGLAITFSY----MLVDLPDVHTVK-PVAT-WATLPLYFGTAIYAFEGIGVVLPLENNMRTPEDFGGTTGVLNTGMVIVACLYTAVGFFGYLKYGEHVEGSITLNLPQGDTLSQLVRISMAVAIFLSYTLQFYVPVNIVEPFVR----------------------SHFDTTRAKDLSATVLRVVLVTFTFLLATCIPNLGSIISLVGAVSSSALALIAPPIIEVITFYNV---GYGRFNWMLWKDVLILIFGLCGFVFGTWASLAQILNDRTH----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PHT8-1", "uniprot_id": "M9PHT8_DROME", "id": "M9PHT8-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MPKRDLTVLHRYFSGRLFPARTQQQQSDQKAIEAAGEMGRTLEITGRQNDKSLEKNPERFTKNVTEKG--------------------------------------------------------------ADPENGDPVRRRGHETSELEAATHLFKGSVGAGLFAMGDCFKNGGLAGATILLPIIAVMCVHCERMLIRGSVLAVERTPGVDFLDYPETVEKCFEHGP-RPLRKMSRVMKLIVEMFLCVTQFGFCAIYFVFITENLHQVLQQ---------------------NGIV-ISMSMVMLITLLPAMIPSLMTNLKYISPVSLFANVALLFGLIATLTI----AFSDGPMPSVGDRHLFTGGAQLALFFGTALFSYEGIALILPLRNSMRRPEKFSTRFGVLNSTMFFTTALFIFTGFVSYVRWGEEVAGSITLNLVVEEVFSQVVKVIAALGVFLGYPIQFFVMIKILWPPLKR---------------------SNNCTQKYPITSQVCLRFFMVMMTFGVALVVPKLNLFISLIGALCSTCLAFVIPVLIDFVTRAQVP---KALGVWSYIKNILILTVAVLGIVTGTYQSIVEIVKEFK-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50944-1", "uniprot_id": "AVT4_YEAST", "id": "P50944-1", "name": "Vacuolar amino acid transporter 4", "aln": "MVTNNGDGEHLGIRRNGNLRHPSNNMKIPRRAQSTVLNSNPFYSRKYSMSTLTPRDICRSVDSRVFVDMSSPNFQTLEDPHRDEIINSVRLNYLNSSKRSSVSHGNEAIPRVNPTKNSSASTIAAANVDSDDDETNLSSAGGDITHDIYKLVKAEDPKRLRRPRSMENVTPKIEHHTKLSSASGLNVPGGFRREFIVNKKRQEHQLNDSASSDFTSHESDSINQSSPSSNQDIDKVPFLTRNFLEFLYVFGHFAGESFEDDFIPDSSNMMIRGEDERSALLSRPDHMKVLPSAKGTTSTKKVFLILLKSFIGTGVLFLPNAFHNGGLFFSVSMLAFFGIYSYWCYYILVQAKSSCG-------VSSFGDIG-----------LKLYGPWMRIIILFSLVITQVGFSGAYMIFTAKNLQAFLDN--------------------VFHVGVLPLSYLMVFQTIIFIPLSFIRNISKLSLPSLLANFFIMAGLVIVIIFTAKRLFFDLMGTPAMGVVYGLNADRWTLFIGTAIFAFEGIGLIIPVQDSMRNPEKFP---LVLALVILTATILFISIATLGYLAYGSNVQTVILLNLPQSNIFVNLIQLFYSIAIMLSTPLQLFPAIKIIENKFFPKFTKIYVKHDDLTTRVELRPNSGKLNWKIKWLKNFIRSIIVIIVVSIAYFGSDNLDKFVSVIGSLACIPLVYIYPSMLHLRGNSLP-ETKGEFWRFKPMLDTILIFFGIASMLYTSYQSIFGV----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..* .*:* : : .. .* . :*: . . * . * :: : ... . : : : . : . . ::. . :: .:. :: : * . * : . ..: : * *: : : . :: : : . . *:. * : * :.. . .. : :: . ", "identical_positions": 14, "similar_positions": 71, "identity": "1.75%" }, { "cls_id": "homologset.agr.SGD:S000005046", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O89042-1", "uniprot_id": "DPOLA_RAT", "id": "O89042-1", "name": "DNA polymerase alpha catalytic subunit", "aln": "MAPVHGDDCKLETSAVSDSGSFVASRARREKKSKKGRQEALERLKKAKAGEKYKYEVEDLTS-VYEEVDEEQY-SKLVQARQDDDWIVDDDGIGYVE-----DGREIFDDDLEDDALDTCGEGSDGK----AHRKDRKDVKKPSVTKPNNIKAMFIASAGKKTTDKTVDLSKDDLLGDILQDLNTETPQ--------IAPPPVLIPKKKRSTGAS---PNPFSVHTATAVPSGKIASPVS------RKEPPLTPVP-----------LKRAEFAGDLAQPECPEDEQESGVIEFEDGDFDEP-MDTEEVDEEEPVTAKIWDQESEPVEGVKHEADPETGTTSFLDSFLPDVSCWDIDQKDENSFLLQEVQVDSNHLPLVKGADDEQVFQFYWLDAYEDPYNQPGVVFLFGKVWVESAKTHVSCCVMVKNIERTLYFLPREMKIDLNTGKETATPITMKDVYEEFDSKISAKYKIMKFKSKIVEKNYAFEIP--DVPEKSEYLEVRYS-----AEVPQLPQNLKGETFSHVFGTNTSSLELFLMNRKIKGPCWLEVKNPQLLNQP-ISWCKFEAMALKPDLVNVIKDVS----PPPLVVMSFSMKTMQNVQNHQHEIIAMAALVHHNFPLDKAPPKPPFQTHFCVVSKP-KDCIFPCAFKEVIKK-KNMEVEVAATERTLLGFFLAKVHKLDPDILVGHNICGFELEVLLQRINECKVPFWSKIG-RLRRSNMPKLGSRSG----FGERNATCGRMICDVEISVKELIH--CKSYHLSELVQQILKT---ERIVIPTENIRNMYS-EPSHLLYLLEHIWKDARFILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLLLHAFYENNYIVPDKQIFRKPQQKPGDEDEEIDGDTNKYKKGRKKAAYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQRVASETLKATEDEEQEQIPELPDPNLDMGILPREIRKLVERRKQVKQLMKQQDLNPDLVLQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTYKGREILMHTKEMVQKMNLEVIYGDTDSIMINTNSTNLEEVFKLGNKVKNEVNKLYKLLEIDIDGVFKSLLLLKKKKYAALVVEPTSDGNYITKQELKGLDIVRRDWCDLAKDTGNFVIGQILSDQSRDTIVENIQKRLIEIGENVLNGSVPVSQFEINKALTKDPQDYPDKKSLPHVHVALWINSQGGRKVKAGDTVSYVICQ--------DGSNLPATQRAYAPEQLQKQDN--LAIDTQYYLAQQIHPVVARICEPIDGIDAVLIALWLGLDS-TQFRVHQYHKDEENDALLGGPAQLTD-EEKYKDCEKFKCLCPSCGTENIYDNVFE-GSGMDMEPSLNRCSNIDCKASPATFMVQLSNKLIMDIRRCIKKYYDGWLICEEPTCRNRIRRLPLHFSRNGPLCPACMKAVLRPEYSDKSLYTQLCFYRYIFDADCALEKLP-EHEKDKLKKQFFTPRVLQDYRKVKNIAEHFLSWSG---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P33609-1", "uniprot_id": "DPOLA_MOUSE", "id": "P33609-1", "name": "DNA polymerase alpha catalytic subunit", "aln": "MAPMHEEDCKLEASAVSDSGSFAASRARREKKSKKGRQEALERLKKAKAGEKYKYEVEDLTS-VYEEVDEEQY-SKLVQARQDDDWIVDDDGIGYVE-----DGREIFDDDLEDDALDTCGKGSDGK----AHRKDRKDVKKPSVTKPNNIKAMFIASAGKKTTDKAVDLSKDDLLGDILQDLNTETAQ--------ITPPPVLIPKKKRSTGAL---LNPFSVHTPKAIPSGKPASPVL------RNEPLLTPIP-----------LKRAELAGELAQPECPEDEQELGVMEFEDGDFDES-MDTEKVDEK-PVTAKTWDQETEPVERVEHEADPERGTTSYLENFLPDVSCWDIDQDDES--IPQEVQVDSSNLPLVKGADDEQVFQFYWLDAYEDPYNQPGVVFLFGKVWIESVKTHVSCCVMVKNIERTLYFLPREMKFDLNTGKETAIPVTMKDVYEEFDSKISAKYKIMKFKSKIVEKNYAFEIP--DVPEKSEYLEVRYS-----AEVPQLPQNLKGETFSHVFGTNTSSLELFLMNRKIKGPCWLEVKNPQLLNQP-ISWCKFEVMALKPDLVNVIKDVS----PPPLVVMSFSMKTMQNVQNHQHEIIAMAALVHHSFALDKAPPEPPFQTHFCVVSKP-KDCIFPCDFKEVISK-KNMKVEIAATERTLIGFFLAKVHKIDPDILVGHNICSFELEVLLQRINECKVPYWSKIG-RLRRSNMPKLGSRSG----FGERNATCGRMICDVEISAKELIH--CKSYHLSELVQQILKT---ERIVIPTENIRNMYS-ESSYLLYLLEHIWKDARFILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLLLHAFYENNYIVPDKQIFRKPQQKLGDEDEEIDGDTNKYKKGRKKATYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQRVTSEVQKATEDEEQEQIPELPDPNLEMGILPREIRKLVERRKQVKQLMKQQDLNPDLVLQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTYKGREILMHTKDMVQKMNLEVIYGDTDSIMINTNSTNLEEVFKLGNKVKSEVNKLYKLLEIDIDAVFKSLLLLKKKKYAALVVEPTSDGNYITKQELKGLDIVRRDWCDLAKDTGNFVIGQILSDQSRDTIVENIQKRLIEIGENVLNGSVPVSQFEINKALTKDPQDYPDRKSLPHVHVALWINSQGGRKVKAGDTVSYVICQ--------DGSNLTATQRAYAPEQLQKLDN--LAIDTQYYLAQQIHPVVARICEPIDGIDAVLIALWLGLDS-TQFRVHQYHKDEENDALLGGPAQLTD-EEKYKDCEKFKCLCPSCGTENIYDNVFE-GSGLDMEPSLYRCSNVDCKVSPLTFMVQLSNKLIMDIRRCIKKYYDGWLICEEPTCCSRLRRLPLHFSRNGPLCPVCMKAVLRPEYSDKSLYTQLCFYRYIFDADCALEKLT-EHEKDKLKKQFFPLRVLQDYRKVKNIAEQFLSWSGYSEVNLSKLFANYAGKS----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09884-1", "uniprot_id": "DPOLA_HUMAN", "id": "P09884-1", "name": "DNA polymerase alpha catalytic subunit", "aln": "MAPVHGDDS------LSDSGSFVSSRARREKKSKKGRQEALERLKKAKAGEKYKYEVEDFTG-VYEEVDEEQY-SKLVQARQDDDWIVDDDGIGYVE-----DGREIFDDDLEDDALDADEKGKDGK----ARNKDKRNVKKLAVTKPNNIKSMFIACAGKKTADKAVDLSKDGLLGDILQDLNTETPQ--------ITPPPVMILKKKRSIGAS---PNPFSVHTATAVPSGKIASPVS------RKEPPLTPVP-----------LKRAEFAGDDVQVESTEEEQESGAMEFEDGDFDEP-MEVEEVDLE-PMAAKAWDKESEPAEEVKQEADSGKGTVSYLGSFLPDVSCWDIDQEGDSSFSVQEVQVDSSHLPLVKGADEEQVFHFYWLDAYEDQYNQPGVVFLFGKVWIESAETHVSCCVMVKNIERTLYFLPREMKIDLNTGKETGTPISMKDVYEEFDEKIATKYKIMKFKSKPVEKNYAFEIP--DVPEKSEYLEVKYS-----AEMPQLPQDLKGETFSHVFGTNTSSLELFLMNRKIKGPCWLEVKSPQLLNQP-VSWCKVEAMALKPDLVNVIKDVS----PPPLVVMAFSMKTMQNAKNHQNEIIAMAALVHHSFALDKAAPKPPFQSHFCVVSKP-KDCIFPYAFKEVIEK-KNVKVEVAATERTLLGFFLAKVHKIDPDIIVGHNIYGFELEVLLQRINVCKAPHWSKIG-RLKRSNMPKLGGRSG----FGERNATCGRMICDVEISAKELIR--CKSYHLSELVQQILKT---ERVVIPMENIQNMYS-ESSQLLYLLEHTWKDAKFILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLLLHAFYENNYIVPDKQIFRKPQQKLGDEDEEIDGDTNKYKKGRKKAAYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQRVASEAQKVTEDGEQEQIPELPDPSLEMGILPREIRKLVERRKQVKQLMKQQDLNPDLILQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTYKGREILMHTKEMVQKMNLEVIYGDTDSIMINTNSTNLEEVFKLGNKVKSEVNKLYKLLEIDIDGVFKSLLLLKKKKYAALVVEPTSDGNYVTKQELKGLDIVRRDWCDLAKDTGNFVIGQILSDQSRDTIVENIQKRLIEIGENVLNGSVPVSQFEINKALTKDPQDYPDKKSLPHVHVALWINSQGGRKVKAGDTVSYVICQ--------DGSNLTASQRAYAPEQLQKQDN--LTIDTQYYLAQQIHPVVARICEPIDGIDAVLIATWLGLDP-TQFRVHHYHKDEENDALLGGPAQLTD-EEKYRDCERFKCPCPTCGTENIYDNVFD-GSGTDMEPSLYRCSNIDCKASPLTFTVQLSNKLIMDIRRFIKKYYDGWLICEEPTCRNRTRHLPLQFSRTGPLCPACMKATLQPEYSDKSLYTQLCFYRYIFDAECALEKLTTDHEKDKLKKQFFTPKVLQDYRKLKNTAEQFLSRSGYSEVNLSKLFAGCAVKS----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P26019-1", "uniprot_id": "DPOLA_DROME", "id": "P26019-1", "name": "DNA polymerase alpha catalytic subunit", "aln": "---------------MSESPS--EPRAKRQRVDKNGRFAAMERLRQLKG-TKNKCKVEDQVDDVYDVVDEREY-AKRAQEKYGDDWIEED-GTGYAE-----DLRDFFEDEDEYSDGEEDRKDSKKKKGVAPNSKKRPRENEKPVTGKASIKNLFSNAVPKK-MDVKTSVKDDDILADILGEIKEEPAATSEKAEKVIAPAKISVTSRKFDAAAAKEYMNSFLNNIKVQEQERKKAEASSDNEMLERILKPKAAVPNTKVAFFSSPTIKKEPMPEKTPAKKATEDPFSDNEMDFSCLDDDENQFDVEKTQQTEKVSQTKTAAEKTSQSKVAEKSAPKKETTGSPKESESEDISRLLNNWESICQMDDDFEKSVLTTEQDSTISSDQQLRFWYWEAYEDPVKMPGEVFLFG-----RTADGKSVCLRVQNINRVLYLLPRQFLLDPISKEPTKQKVTVADIYKEFDSEVANQLKLEFFRSRKVTKSFAHHAIGIEVPQSCDYLEVHYDGK---KPLPNLSADKKYNSIAHIFGATTNALERFLLDRKIKGPCWLQVTGFKVSPTP-MSWCNTEVTLTEPKNVELVQDKGKPAPPPPLTLLSLNVRTSMNPKTSRNEICMISMLTHNRFHIDRPAPQPAFNRHMCALTRP-AVVSWPLDLNFEMAKYKSTTVHKHDSERALLSWFLAQYQKIDADLIVTFDSMDCQLNVITDQIVALKIPQWSRMG-RLRLS--QSFGKR--------LLEHFVGRMVCDVKRSAEECIR--ARSYDLQTLCKQVLKLKESERMEVNADDLLEMYE-KGESITKLISLTMQDNSYLLRLMCELNIMPLALQITNICGNTMTRTLQGGRSERNEFLLLHAFHEKNYIVPDKKPVSK-RSGAGDTDATLSGADATMQT-KKKAAYAGGLVLEPMRGLYEKYVLLMDFNSLYPSIIQEYNICFTTVQ----------QPVDADELPTLPDSKTEPGILPLQLKRLVESRKEVKKLMAAPDLSPELQMQYHIRQMALKLTANSMYGCLGFAHSRFFAQHLAALVTHKGREILTNTQQLVQKMNYDVVYGDTDSLMINTNITDYDQVYKIGHNIKQSVNKLYKQLELDIDGVFGCLLLLKKKKYAAIKLSKDSKGNLRREQEHKGLDIVRRDWSQLAVMVGKAVLDEVLSEKPLEEKLDAVHAQLEKIKTQIAEGVVPLPLFVITKQLTRTPQEYANSASLPHVQVALRMNRERNRRYKKGDMVDYVICL--------DGTTNAAMQRAYHLDELKTSEDKKLQLDTNYYLGHQIHPVVTRMVEVLEGTDASRIAECLGMDP-TKFRQNAQRTQRENTEQSEGESLLKTTLQLYRLCEPFRFQCVTCKTEQLMASAYRPGPSNSHIAVLQQCAKSECQTAPIQYLASVRNQLQLSMRQYVQRFYKNWLVCDHPDCNFNTRTHSLRKKSHRPLCQKCRSGSLLRQYTERDLYNQLCYLRFMFDLG----------KQTLQQKPTLTPELEQAYQLLYETVDQQLQSSSYVIISLSKLFARSLAQMSLQPSVAQPQIEAIPSALADVV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13382-1", "uniprot_id": "DPOLA_YEAST", "id": "P13382-1", "name": "DNA polymerase alpha catalytic subunit A", "aln": "---------------------------MSSKSEKLEKLRKLQAARNGTSIDDYEGDESDGDR-IYDEIDEKEYRARKRQELLHDDFVVDDDGVGYVDRGVEEDWREVDNSSSDEDTGNLASKDSKRK----KNIKREKDHQITDMLRTQHSKSTLLAHAKKSQKKSIPIDNFDDILGEFESGEVEKPNILLP---SKLRENLNSSPTSEFKSSIKRVNGNDESSHDAGISKKVKIDPDSSTDKYLEIESSPLKLQSR-KLRYANDVQDLLDDVENSPVVATKRQNVLQDTLLANPPSAQSLADEEDDEDSDEDIILKRRTMRSVTTTRRVNIDSRSNPSTSPFVTAPGTPIGIKGLTPSKSLQSNTDVATLAVNVKKEDVVDPETDTFQMFWLDYCEVNN----TLILFG-KVKLKDDNCVSAMVQINGLCRELFFLPREG-------------KTPTDIHEEIIPLLMDKYGLDNIRAKPQKMKYSFELP--DIPSESDYLKVLLPYQTPKSSRDTIPSDLSSDTFYHVFGGNSNIFESFVIQNRIMGPCWLDIKGADFNSIRNASHCAVEVSVDKPQNITPTTTKT----MPNLRCLSLSIQTLMNPKENKQEIVSITLSAYRNISLDSPIPENIKPDDLCTLVRPPQSTSFPLGLAALAKQKLPGRVRLFNNEKAMLSCFCAMLKVEDPDVIIGHRLQNVYLDVLAHRMHDLNIPTFSSIGRRLRRTWPEKFGRGNSNMNHFFISDICSGRLICDIANEMGQSLTPKCQSWDLSEMYQVTCEK---EHKPLDIDYQNPQYQNDVNSMTMALQENITNCMISAEVSYRIQLLTLTKQLTNLAGNAWAQTLGGTRAGRNEYILLHEFSRNGFIVPDKEGNRSRAQKQRQNEENADAPVN-----SKKAKYQGGLVFEPEKGLHKNYVLVMDFNSLYPSIIQEFNICFTTVDR---------NKEDIDELPSVPPSEVDQGVLPRLLANLVDRRREVKKVMKT-ETDPHKRVQCDIRQQALKLTANSMYGCLGYVNSRFYAKPLAMLVTNKGREILMNTRQLAESMNLLVVYGDTDSVMIDTGCDNYADAIKIGLGFKRLVNERYRLLEIDIDNVFKKLLLHAKKKYAALTVNLDKNGNGTTVLEVKGLDMKRREFCPLSRDVSIHVLNTILSDKDPEEALQEVYDYLEDIRIKVETNNIRIDKYKINMKLSKDPKAYPGGKNMPAVQVALRMRKAG-RVVKAGSVITFVITKQDEIDNAADTPALSVAERAHALNEVMIKSNN-LIPDPQYYLEKQIFAPVERLLERIDSFNVVRLSEALGLDSKKYFRREGGNNNGEDINNLQPLETTITDVERFKDTVTLELSCPSCDKRFPFG-----GIVSSNYYRVSYNGLQCKHCEQLFTPLQLTSQIEHSIRAHISLYYAGWLQCDDSTCGIVTRQVSVFGKR---CLNDGCTGVMRYKYSDKQLYNQLLYFDSLFDCE--------KNKKQELKPIYLPDDLDYPKEQLTESSIKALTEQNRELMETGRSVVQKYLNDCGRRYVDMTSIFDFMLN-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .* : :: :: .. . : . .* :*: :**.:* :: * **:: :* * **.: * *:. :.. : . : :... * . * . : : * : . *. . . *.:*.:: :. : . : . . * : . * . . . :: . : . : :: . : . . * .: . * . : . : . : ::::: : * ::*** * : ::.: * *::***: : *:::*: : : : :::: .::.. ::*...:**:* :. : . ::: *:** .:. :* *:::.:* *****::.. .. * * *. :*. : * * :::.::* * : ::** :: .:. : :* . *: .:*.: :* :* : : *. .*::::. * * : *.*::: . . *:*: .:: : * :* :* **: : .:* : **::**: . : : .:*:.*. : : : *: : : *. . . : :. : .: .::::.*: *:**:.** ::** * *: ***::*** * .:.:*****: . . : : .. *** * ****::* *::.:::*::************:*******: : : :::* :* .. : *:** : .**: *::**::* : .*. :* .*** **************: ***:*: ** *** ****** :*:::.:.** *:******:**:*. : :. *:* .* **: *: **:*** ** *** ******: :. ..** * ****: **::. *: .. *:. :**:: : :: : * .* :: . : : : *. *:: *: *.. .:* *:*** :. * * *. : :** * . .. :**: ::: .: * *.:*** :**.. * *: * ::. :. :: **:*. . ** . ..: *: : :: :. * :* .. * . : . : .: .:: .:* :. :* .** *:.. * * .: . .. : :*:::.**.** : :** :: : :. : . : : : * .. ", "identical_positions": 287, "similar_positions": 438, "identity": "18.29%" }, { "cls_id": "homologset.agr.SGD:S000005050", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CHC4-1", "uniprot_id": "SYNJ1_MOUSE", "id": "Q8CHC4-1", "name": "Polyphosphatidylinositol phosphatase SYNJ1", "aln": "MAFSKGFRIYHKLDPP-PFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYAKVLDAYGLLGVLRLNLGDTMLHYLVLVTGCMSVGK-IQESEVFRVTSTEFISLRV--------------------------------------------------DASDEDRISEVRKVLNSGNFYFAWSASGVSLDLSLNAHRSMQEHTTD-NRFFWNQSLHLHLKHYG----------VNCDDWLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVIYLDDCVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKDLYGKQIVVNLLGSKEGEHMLSKAFQSHLKAS---EHASDIHMVSFDYHQMVKGGKAEKLHSILKPQVQKFLDYG-FFYFDGSE-VQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR--FQEVFRSMWSVNGDSISKIYAGTGALEG-------KAK---LKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGSLRVSEQTLQS---------ASSKVLKNMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVNASTTNQKLWAVELQKTISR-DNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFVEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQN---WDSLIAGDQLINQKNAGQIFRGFLEGKVTFAPTYKYDLFSEDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQKIYKEVIAVQGPPDGTVLVSIKS-SAQESTFFDDALIDELLRQFAHFGEVILIRFVEDKMWVTFLEGSSALNALSLNGKELLNRTITITLKSPDWIKHLEEEMSLEKISVTLPSSASSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQP-SSSSGLGTSPSSSPRTSPCQSPTVPEYSAPSLPIRPSRAPSRTPGPPSS-----------QGSPVDTQPAA---QKDSSQTLEPKRPPPPRPVAPPARPAPPQRPPPPSGARSPAPARKEFGGVGAPPSPGVARREIEAPKSPGTARKDNIGRNQPS------------PQAGLAG-------PGPAGYGAARPTIPARAGVISAPQSQARVCAGRPTPDSQSKPSETLKGP-AVLPEPLKPQAAFPQQPSLPTPAQKLQDPLVP--------------IAAPTMPPSGPQPNLETP---------PQPPPRSRSSQSLPSDSSPQLQQEQPTG-QVKINGISGVKQEPTLKSDPFEDLS----LSVLAVSKAQPSVQISPVLTPDPKM-LIQLPSASQSQVNPLSSVSCMPTRPPGPEESKSQESMGSSANPFPS-LPCRNPFTDRTAAPGNPFRVQSQESEATSWLSKEEPVPNSPFPPLMPLSHDTSKASSSLGGFEDNFDLQSQSTVKTS--NPKGWVTFDEDDNFPTT--GKSKSVCPDLVGNAPASFD-------DDWSKGASVSFCVLPARRPPPPPPPVPLLPPGTTSSAGPSTTLPSKAPSTLDFTER", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62910-1", "uniprot_id": "SYNJ1_RAT", "id": "Q62910-1", "name": "Polyphosphatidylinositol phosphatase SYNJ1", "aln": "MAFSKGFRIYHKLDPP-PFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYAKVLDAYGLLGVLRLNLGDTMLHYLVLVTGCMSVGK-IQESEVFRVTSTEFISLRV--------------------------------------------------DASDEDRISEVRKVLNSGNFYFAWSASGVSLDLSLNAHRSMQEHTTD-NRFFWNQSLHLHLKHYG----------VNCDDWLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVIYLDDCVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKDLYGKQIVVNLLGSKEGEHMLSKAFQSHLKAS---EHASDIHMVSFDYHQMVKGGKAEKLHSVLKPQVQKFLDYG-FFYFDGSA-VQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR--FQEVFRSMWSVNGDSISKIYAGTGALEG-------KAK---LKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGSLRVSEQTLQS---------ASSKVLKNMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVNASTTNQKLWAVELQKTISR-DNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFVEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQN---WDSLIAGDQLINQKNAGQIFRGFLEGKVTFAPTYKYDLFSEDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQKIYKEVIAVQGPPDGTVLVSIKS-SAQENTFFDDALIDELLQQFAHFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITITLKSPDWIKTLEEEMSLEKISVTLPSSTSSTLLGEDAEVSADFDMEGDVDDYSAEVEELLPQHLQP-SSSSGLGTSPSSSPRTSPCQSPTAPEYSAPSLPIRPSRAPSRTPGPLSS-----------QGAPVDTQPAA---QKESSQTIEPKRPPPPRPVAPPARPAPPQRPPPPSGARSPAPARKEFGGVGAPPSPGVTRREMEAPKSPGTARKDNIGRNQPS------------PQAGLAG-------PGPSGYGAARPTIPARAGVISAPQSQARVSAGRLTPESQSKPLETSKGP-AVLPEPLKPQAAFPPQPSLPTPAQKLQDPLVP--------------IAAP-MPPSIPQSNLETP---------PLPPPRSRSSQSLPSDSSPQLQQEQPTGQQVKINGACGVKQEPTLKSDPFEDLS----LSVLAVSKAQPSAQISPVLTPDPKM-LIQLPSASQSKVNSLSSVSCMLTMPPVPEQSKSQESVGSSANPFPS-LPTRNPFTDRTAAPGNPFRVQSQESEATSWLSKEEPVSNSPFPPLMPLSHDMSKPSSSLDGFEDNFDLQSQSTVKTS--NPKGWVTFDEDEDFPTK--GKSRSVYPDSLGNTAASFD-------DDWSKGTNVSFCVLPARRPPPPPPPVPLLPPGTTSSAGPSTTLSSKASPTLDFTER", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43426-1", "uniprot_id": "SYNJ1_HUMAN", "id": "O43426-1", "name": "Polyphosphatidylinositol phosphatase SYNJ1", "aln": "MAFSKGFRIYHKLDPP-PFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAYGLLGVLRLNLGDTMLHYLVLVTGCMSVGK-IQESEVFRVTSTEFISLRI--------------------------------------------------DSSDEDRISEVRKVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTD-NRFFWNQSLHLHLKHYG----------VNCDDWLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKAS---EHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLDYG-FFYFNGSE-VQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR--FQEVFRSMWSVNGDSISKIYAGTGALEG-------KAK---LKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGSLRVSEQTLQS---------ASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISR-DNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQN---WDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKS-SLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQP-SSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSA-----------QSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPS------------PQAGLAG-------PGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGS-TFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVP--------------VAAP-MPQSGPQPNLETP---------PQPPPRSRSSHSLPSEASSQPQ--------VKTNGISDGKRESPLKIDPFEDLS----FNLLAVSKAQLSVQTSPVPTPDPKR-LIQLPSATQS--NVLSSVSCMPTMPPIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKIS--NPKGWVTFEEEEDFGVK--GKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPP--PVPLLPPGTSPPVDPFTTLASKASPTLDFTER", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B1N6-1", "uniprot_id": "A0A8M2B1N6_DANRE", "id": "A0A8M2B1N6-1", "name": "Synaptojanin-1", "aln": "MAFSKGYRIYHKLDPP-PYSVIVETRNREECLMFESGAVAVLSAAEKETIKASYTKMLDAYGILGVLRLNLGDSMLHSLVVVTGCSSVGK-VQDSEVFRVTGTDFVSLKN--------------------------------------------------DPTDEDRIADVRKVLNSGNFYFAWSSTGVSLDLSLNAHRRIREDTSD-NRFFWNQSLHLHLKHYG----------VNCDDWLLRLMCGGVEIRTIYAGHKQAKACVISRLSSERAGTRFNVRGTNDDGQVANFVETEQIIFLDDKVSSFIQIRGSIPLFWEQPGIQVGSHRVKLSRGFEANAPAFERHFSALKRLYGKQLIINLLGMKEGEHMLSKAFQSHLKAS---EHSNAVKMLNFDYHQMVKGGKTEKLQTVLKPQISKFVEDCDFFYYSGETGIQRCQSGTIRSNCLDCLDRTNSVQAFIALEMLPKQLEAMGLTEKPQLVAR--FQEVFRSMWSTNGDSISKIYAGTGALDG-------KAKGGKLKDGARSVTRTIQNNFFDSSKQEAIDILRLGSTLNSDLADKARALLTTSSLYVSEPILQS---------ASPRVLLGMCQNHFKYTRPKKIRVCVGTWNVNGGKQFRSIAFRNHTLNDWLLDAPKKAGHPEFQDVKNNPVDIFAIGFEEMVELNAGNIVSASTTNQKLWAAELQKNISR-DQRYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGGVAIRMLFHTTSICFVCSHFAAGQSQVKERNDDYNEIARKLSFPMGRLLYSHDYVFWCGDFNYRINIPNEEVKELIRQQN---WDALIGGDQLVEQKNAGQVFRGFIEGKLDFAPTYKYDLFSEDYDTSEKCRTPAWTDRVLWKRRKWNFDKTAEELELNVVGAPVNEEEQYPWSPGDLKYYGRAELKTSDHRPVVAIIDVDILEVDPEARHQVYKEVIALQGPPDGTILVSLCS-SGPDD-YFDDALIDDLLDKFANFGEVILIRFVEEKMWVTFLEGYSALAALSLSGSTVNGKTIDIRLRSPGWIKSLEEEMSVERICGSIPTSTSSTLLAENSDLGEEYDMEGDVD---EEVEDILPQHLQP-GAGMDLSASPATSPRTSPCPSPTHG---EPAPPIRPSRAPPRTAGPPQGGLSPASIRRELAGSPVDGQPAG----APFSQGLEPKRPPPPRPNAPPARPAPPQRPPPPSGGRSPTPVRKDSAGFAEPLNLEFDLTDNEGQKSPALARADAAGRGQATGPAPGGIPRPIPPRAGVISVTPQARPPPPAHPGAPRPTAEVHPGAP-RPSPDNHPGAPRPTAEPQSKPSELPLGPPPTLPGPVRPQMTSPMQPQSVSPVQPPVQPQLPPPIQSQLPPPMQPTLPAPLMPQQAPQTSAGAAAAPQPGLASPKPPPRSRSSHALPPESAPAPT--------TQAKNMNGVQREAQWNLDPFDMLNPQSLFQNTPFTASLPRSSSSSTSTPSPSSSSSTLPSNLSLFSAPDTSSASCLLAPPAPSRSKSQETLRCSPNPFLTDIQPR-PNSTNPFTSGLQFSPRRS---LTPDFYTQMQASKPDFNRAMSAVGHSSTLPPTFS--RQQSLVTATAPAPNK--QTQKWVTFDDDLDFLSKRVGTGPLASPLPFPQTQSSFP--------SSGFGMDNNWASLPTSAFPAIPPPVPTR----TNTSIKNAQLPSRN----DFTER", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9D2G5-1", "uniprot_id": "SYNJ2_MOUSE", "id": "Q9D2G5-1", "name": "Polyphosphatidylinositol phosphatase SYNJ2", "aln": "MALSKGLRLLARLDPTGPSSVLLEARGRGDCLLFEAGAVATLAPEEKEVIKGLYSKLTDAYGCLGELRLQSGGVPLSFLVLVTGCMSVGR-IPDAEIYKITATELYPLQE--------------------------------------------------EAKEEDRLPTLKKILSSGVFYFAWPNDGACFDLTIRAQKQGDDGSEWGTSFFWNQLLHVPLRQHQ----------VNCHNWLLKVICGVVTIRTVYASHKQAKACLISRISCERAGARFLTRGVNDDGHVSNFVETEQTIYMDDGVSSFVQIRGSVPLFWEQPGLQVGSHHLRLHRGLEANAPAFERHMVLLKEQYGKQVVVNLLGSRGGEEVLNRAFKKLLWAS---CHAGDTPMINFDFHQFAKGRKLEKLENLLRPQLQLHWEDFGVFAK-GENVSPRFQKGTLRMNCLDCLDRTNTVQCFIALEVLHLQLESLGLNSKP-IIDR--FVESFKAMWSLNGHSLSKVFTGSRALEG-------KAKVGKLKDGARSMSRTIQSNFFDGVKQEAIKLLLVGDVYNEESTDKGRMLLDNTALL-----------------ATPRILKAMTERQSEFTNFKRIQIAVGTWNVNGGKQFRSNLLGTAELTDWLLDAPQLSGAVDSQD-DGSPADVFAIGFEEMVELSAGNIVNASTTNRKMWGEQLQKAISR-SHRYILLTSAQLVGVCLYIFVRPYHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQLHSTSFCFVCSHLTAGQSQVKERNEDYREITHKLSFPSGRNIFSHDYVFWCGDFNYRIDLTYEEVFYFVKRQD---WKKLMEFDQLQLQKSSGKIFKDFHEGAVNFGPTYKYDVGSAAYDTSDKCRTPAWTDRVLWWRKKHPYDKTAGELNLLDSDLDGDPQIRHTWSPGTLKYYGRAELQASDHRPVLAIVEVEVQEVDVGARERVFQEVSSVQGPLDATVVVNLQSPTLEEKNEFPEDLRTELMQTLGNYGTIILVRINQGQMLVTFADSHSALSVLDVDGMKVKGRAVKIRPKTKDWLEGLREELLRKRDSMAPVSPTANSCLLEENFDFSSLDYESEGDVLEEDEDYLVDGFGQPVVSDSELGGDNSSDT--MSSLTPASK---SPALAKKKQHPTYK------------------------------------------------------------------AGLMVKKSASDASISSGTHGQYSILQTAKLLPGAPQQPPKARTGISKPY-----------------------------------------NVKQIKTTNAQEAEAAIRCLLEASGGVPESAPGA--IPLR----------NQGSSKPEATLGPPALP----------------------RRPAPRVPTM----------KKPTLRRTGKPMLPEENFEPQ------------------------PVHFTMAS-------QEMNLETPPPITATPIPPVPKP--RTLQPGKGVEGRPSSGKPEPDEAPSVTGTVESPPPEAQEAPSLAPKVPPRRKKSAPAAFHLQVLQNNSQVLQGLTCSSS-SPPSLKPDTHPLCLQ-VALGTSSARSPETHGPRVTEPEAASFHGNYPDPFWSLLHHPKLLNN-TWLSKSSEPLDVGSRNPERT----------HTEPAQVNASLAERGLPPDHGGKDLSHWVTASNKDKRTTLGV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O55207-1", "uniprot_id": "SYNJ2_RAT", "id": "O55207-1", "name": "Polyphosphatidylinositol phosphatase SYNJ2", "aln": "MALSKGLRLLARLDPTGPSSVLLEARGRGDCLLFEAGAVATLAPEEKEVIKGLYGKPTDAYGCLGELSLKSGGVPLSFLVLVTGCTSVGR-IPDAEIYKITGTEFYPLQE--------------------------------------------------EAKEEDRLPALKKILSSGVFYFAWPNDGACFDLTIRAQKQGDDCSEWGTSFFWNQLLHVPLRQHQ----------VNCHDWLLKVICGVVTIRTVYASHKQAKACLISRISCERAGARFLTRGVNDDGHVSNFVETEQAIYMDDGVSSFVQIRGSVPLFWEQPGLQVGSHHLRLHRGLEANAPAFERHMVLLKEQYGQQVVVNLLGSRGGEEVLNRAFKKLLWAS---CHAGDTPMINFDFHQFAKGRKLEKLENLLRPQLKLHWDDFGVFAK-GENVSPRFQKGTLRMNCLDCLDRTNTVQCFIALEVLHLQLESLGLNSKP-ITDR--FVESFKAMWSLNGHGLSKVFTGSRALEG-------KAKVGKLKDGARSMSRTIQSNFFDGVKQEAIKLLLVGDVYNEESTDKGRMLLDNTALLGLGSNKQNSLSGMLDGKATPRILKAMTERQSEFTNFKRIQIAMGTWNVNGGKQFRSNLLGTTELTDWLLDAPQLSGAVDSQD-DGGPADIFAVGFEEMVELSAGNIVNASTTNRKMWGEQLQKAISR-SHRYILLTSAQLVGVCLYIFVRPYHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQFHSTSFCFICSHLTAGQSQVKERNEDYREITHKLSFPSGRNIFSHDYVFWCGDFNYRIDLTYEEVFYFVKRQD---WKKLMEFDQLQLQKSSGKIFKDFHEGTINFGPTYKYDVGSAAYDTSDKCRTPAWTDRVLWWRKKHPYDKTAGELNLLDSDLDGDANIRHTWSPGTLKYYGRAELQASDHRPVLAIVEVEVQEVDVGARERVFQEVSSVQGPLDATVIVNLQSPTLEERNEFPEDLRTELMQTLGNYGTIILVRINQGQMLVTFADSHSALSVLDVDGMKVKGRAVKIRPKTKDWLEGLREELIRKRDSMAPVSPTANSCLLEENFDFTSLDYESEGDVLEDDEDYLADEFGQPVVSDSELGGDDSSDT--MSASTPASK---SPALAKKKQHPTYKDDADLMT-------------LKLELEVAGNFRHRSPSRSLSVPNRPRP--------PHPPQRPPPPTGLMVKKSASDASISSGTHGQYSILQTAKLLPGAPQQPPKARTGISKPY-----------------------------------------NVKQIKTTNAQEAEAAIRCLLEAGGGVPESAPGA--TPLR----------NQGSSKPEASLGPPVLP----------------------RRPVPRVPTM----------KKPTLRRTGKPMLPEEQCEQQ------------------------PVHFTMAS-------QEMNLETPPPITA-PIPPVPKP--RTFQPGRGVERRPSGGKPEPDDAPPVTGAVELSSPEAPEAPSLAPKVPPRRKKSAPAAFHLQVLQSNSQLLQGLTCSSS-SPSPPKPDTPLLYPQ-MALGTSSAISPETDGPRVTEPEAASFHGDYPDPFWSLLHHPKLLNNNTWLSKSSEPLDLGSRTPERT----------HTDSAQVNASVVERGLPPDHGGKDFSHWMAASNKDKRTTLGV-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15056-1", "uniprot_id": "SYNJ2_HUMAN", "id": "O15056-1", "name": "Polyphosphatidylinositol phosphatase SYNJ2", "aln": "MALSKGLRLLGRLGAEGDCSVLLEARGRDDCLLFEAGTVATLAPEEKEVIKGQYGKLTDAYGCLGELRLKSGGTSLSFLVLVTGCTSVGR-IPDAEIYKITATDFYPLQE--------------------------------------------------EAKEEERLIALKKILSSGVFYFSWPNDGSRFDLTVRTQKQGDDSSEWGNSFFWNQLLHVPLRQHQ----------VSCCDWLLKIICGVVTIRTVYASHKQAKACLVSRVSCERTGTRFHTRGVNDDGHVSNFVETEQMIYMDDGVSSFVQIRGSVPLFWEQPGLQVGSHHLRLHRGLEANAPAFDRHMVLLKEQYGQQVVVNLLGSRGGEEVLNRAFKKLLWAS---CHAGDTPMINFDFHQFAKGGKLEKLETLLRPQLKLHWEDFDVFTK-GENVSPRFQKGTLRMNCLDCLDRTNTVQSFIALEVLHLQLKTLGLSSKP-IVDR--FVESFKAMWSLNGHSLSKVFTGSRALEG-------KAKVGKLKDGARSMSRTIQSNFFDGVKQEAIKLLLVGDVYGEEVADKGGMLLDSTALL-----------------VTPRILKAMTERQSEFTNFKRIRIAMGTWNVNGGKQFRSNVLRTAELTDWLLDSPQLSGATDSQD-DSSPADIFAVGFEEMVELSAGNIVNASTTNKKMWGEQLQKAISR-SHRYILLTSAQLVGVCLYIFVRPYHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQFHSTSFCFICSHLTAGQSQVKERNEDYKEITQKLCFPMGRNVFSHDYVFWCGDFNYRIDLTYEEVFYFVKRQD---WKKLLEFDQLQLQKSSGKIFKDFHEGAINFGPTYKYDVGSAAYDTSDKCRTPAWTDRVLWWRKKHPFDKTAGELNLLDSDLDVDTKVRHTWSPGALQYYGRAELQASDHRPVLAIVEVEVQEVDVGARERVFQEVSSFQGPLDATVVVNLQSPTLEEKNEFPEDLRTELMQTLGSYGTIVLVRINQGQMLVTFADSHSALSVLDVDGMKVKGRAVKIRPKTKDWLKGLREEIIRKRDSMAPVSPTANSCLLEENFDFTSLDYESEGDILEDDEDYLVDEFNQPGVSDSELGGDDLSDVPGPTALAPPSK---SPALTKKKQHPTYKDDADLVE-------------LKRELEAVGEFRHRSPSRSLSVPNRPRP--------PQPPQRPPPPTGLMVKKSASDASISSGTHGQYSILQTARLLPGAPQQPPKARTGISKPY-----------------------------------------NVKQIKTTNAQEAEAAIRCLLEARGGASEEALSA--VAPRDLEASSEPEPTPGAAKPETPQAPPLLP----------------------RRPPPRVPAI----------KKPTLRRTGKPLSPEEQFEQQ------------------------TVHFTIGP-------PETSVEAPPVVTAPRVPPVPKP--RTFQPGKAAE-RPSHRKPASDEAPPGAGASVPPP---LEAPPLVPKVPPRRKKSAPAAFHLQVLQSNSQLLQGLTYNSSDSPSGHPPAAGTVFPQGDFLSTSSATSPDSDGTKAMKPEAAPLLGDYQDPFWNLLHHPKLLNN-TWLSKSSDPLDSGTRSPKRD----------PIDPVSAGASAAKAELPPDHEHKTLGHWVTISDQEKRTALQVFDPLAKT----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P50942-1", "uniprot_id": "INP52_YEAST", "id": "P50942-1", "name": "Polyphosphatidylinositol phosphatase INP52", "aln": "MKILLSKQQTRKIAIVSETHGLVFRPINSKNSRRSTCAVELVPKAELNGNGFRRLSNHEIYGFIGLIEIEG----LMFIATITGKSKVAQPIPNKTVNKIYAVDFFCLNNSKWDFMDIDSSGYPIVTNDGDFAISSPPSISTHSSRSSLRSSSSRSLNAQEQAPKHPCHELRKLLSNGSFYYSTDFDLTCTLQKRGFTEHSLSFDDFDREFMWNSFLMDEIITYRDRLDVTAKELLDQRGFLTTVIRGFAETIFSYINRLKVGLTIISRQSWKRAGTRFNARGIDDDGHVANFVETEMIMYSSQYCYAFTQIRGSLPIFWEQDTSLIS-PKIQITRSVEATQPTFDEHFIRLFKKYGPVHIINLLSTKSSEIQLSRRYKEQLKNSEKMKIGRDVFLTSFDFHRETSQDGFAAASRIIPKIRNTILDAGYFSYDVKEGRLISEQDGVFRTNCLDCLDRTNLIQQTISLAVFKLFLEDFRLVKPSSFIDDNEFVQKVNALWADNGDQISQIYTGTNALKSSYSRKGKMSFSGALSDATKSVSRMYINNFVDKGKQQNIDTLLG------KLPHQQVVELYDP--------------------ICEYVNERLLESEEKFTTHSNINLFVGTFNVNGNS-------RRADLSKWLFPIG-----------DKFKPDVVVLGLQEVIELTAGSILNADYTKSSFWETMVTDCLNQYEEKYLLLRVEQMSSLLILFFARSDRAYNIKEVGGSTKKTGFGGITGNKGAVAIRFDYGATSFCFVNTHLSAGASNIDERRNDYNNIYRNITFPRSKTIPHHDSLFWLGDLNYRITLTNDEVRRELRAQKDGYIDRLLQYDQLTQEINEGVVFQGFKEPTLQFRPTYKYDYGTDNYDTSEKARTPSWTDRIIYKGE-----------------------------NLHPLAYSDAPLKISDHKPVYAAYRANVKFVDEKEK-----------------------------------------------------------------------LNLVEKLYAEYKNTHPEALTTGPDELSHARMEKQKESIPLDATVQSAGIKLIDLDDT--------------------------------SSCVSPLLS---------------------------------------------------------------------------------------------------------------GPSPQPSVVGPGGLSNVSPDKSKLNVLPPPPPT----------------------------------------------SRHNKEPSSKLLSPTKEISIVSVSPRKGE-----------------SNLPALERHSTPKPLP------------------------PVPALSLS----------KPVSLQKSSSELQHAKETIDN-----------------------------------------------GKIVPRPCPPIRRK--SSTAPDEISTSTKNSGVSTTEDPEPAKASTKPEKPPVVKKPHYLSVAANKLNTSQEHSIKVSPSNSKSEEELPCKKKSKPKVPAKNPELEKLSVHPLKPCDPN---------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . : :: :: . . .: :* :. * : . : ** :* : :: * :. :** .*.: : : : :: ..:: *. : :. ::*:*..* **:: . . . *:**. * : : :. .:* :: * . * : :. ::** * :*:*:** .** :***:*:****** :: .: :* *****:*:**** :. :::: *..**. *:*:.*: * ** ::***. : .* *.: ::. * * . : .**:*: .. :: . : . . *.*..* ********** :* :.* :: *: : * . . : * : ..::*: **. :*::::*: **.. : *.*.::*::* .**.* **: *. * . ..: * : : : ::: ..*.: :**:****.. *..**: *:..:*::*::**.**.*:.*. *: .:* : . :.: ..:*:** *: .: : .* *. :. *::*. .* ***:** :****.*.**: :**:**: :*::** *::.**.:*: :* ::: ** .: : ** :** **:**** :. :** :: *. . *: *** : . * :*:.* * : * ****** : ****:*.***:****::: . *. * *: ***:** * :: *: : * :. . . :. . * : ::. * : . . . . . :* . . . . : . . :* * . . ::. : . .* . . . . . : . . . . ", "identical_positions": 222, "similar_positions": 312, "identity": "12.73%" }, { "cls_id": "homologset.agr.SGD:S000005051", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CR11-1", "uniprot_id": "YETS4_MOUSE", "id": "Q9CR11-1", "name": "YEATS domain-containing protein 4", "aln": "MFKRMAEFGPDSGGRVKGVTIVKPIVYGNVARYFGKKREEDG---HTHQWTVYVKPYRNEDMSAYVKKIQFKLHESYGNPLRVVTKPPYEITETGWGEFEIIIKIFFIDPN-ERPVTLYHLLKLFQS--------------DTNAMLGKKTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQTKDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95619-1", "uniprot_id": "YETS4_HUMAN", "id": "O95619-1", "name": "YEATS domain-containing protein 4", "aln": "MFKRMAEFGPDSGGRVKGVTIVKPIVYGNVARYFGKKREEDG---HTHQWTVYVKPYRNEDMSAYVKKIQFKLHESYGNPLRVVTKPPYEITETGWGEFEIIIKIFFIDPN-ERPVTLYHLLKLFQS--------------DTNAMLGKKTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQAKDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VM63-1", "uniprot_id": "Q9VM63_DROME", "id": "Q9VM63-1", "name": "YEATS domain-containing protein 4", "aln": "----MTDFGGDSGGRLKGVTIVKPIVYGNIARSFGKKREEDG---HTHQWKVYLKPYFNEDMSIYVKKVHFKLHESYANPNRIVVKPPYEITETGWGEFEVIIKIYFNDQS-ERPVTCYHILKLFQSP------VVDGELSSSTTMDTKKGLVSESYEEIVFQEPTQILQHYLLLSEQSANGLLTHDTDFEEKKTKTLDNIVNVKQKVKGEIVTLKDKLKLARETISKFKAELAKVQKQPA----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53930-1", "uniprot_id": "AF9_YEAST", "id": "P53930-1", "name": "Protein AF-9 homolog", "aln": "-------MAPTISKRIKTLSVSRPIIYGNTAKKMGSVKPPNAPAEHTHLWTIFVRGPQNEDISYFIKKVVFKLHDTYPNPVRSIEAPPFELTETGWGEFDINIKVYFVEEANEKVLNFYHRLRLHPYANPVPNSDNGNEQNTTDHNSKDAEVSSVYFDEIVFNEPNEEFFKILMSRPG------------NLLPSNKTDDCVYSKQLEQEEIDRIEIGIEKVDKEIDELKQKLENLVKQEAINGS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . *:* ::: :**:*** *: :*. : :. *** *.:::: ***:* ::**: ****::* ** * : **:*:********:: **::* : *: :. ** *:*. : . : * ::*::*::*. : : * :. :. *: . ** :: :: : *. :* :: :: :: ", "identical_positions": 56, "similar_positions": 70, "identity": "22.86%" }, { "cls_id": "homologset.agr.SGD:S000005052", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3V3E1-1", "uniprot_id": "UBS3A_MOUSE", "id": "Q3V3E1-1", "name": "Ubiquitin-associated and SH3 domain-containing protein A", "aln": "---------------------MAAGETQLYAKVSNKLKGRSTP------SLLDPLLAMGFPTHTALKALAATGRKTAEAAADWLHGHCNDPSLDDPIPQEYALFLCPTGPLLEKLQEFWRESRRQCAKNRAHEVFPHVTLCDFFTCEDQKVECLYEALRRAGDRILGSFPTLVPLVLHSSISYLGFFINDSPADAIREFAMAFATEAA--VLAD--------------------------------------CTIKPCTKQLHLTLAHKFYPHHQRTLEQLAKAIQPSHSCQWTAALYSRDMRFVHYQTLKALFQYKPQNADELMLSAGDYIFVDPTQQEEASEGWAIGISHRTGCRGFLPENYTERANEADTWVKHRTYTFNLAMDLNSR----------------------------KDFE-----ASCRGNGEPHTPSMSKSVSSIQALQATIS-------------------------------------------------------------------RRGILVVRHGERVDQVFGKSWLQQCTTADGKYYRPDLNFPRSLPRRSNGIKDFENDPPLSSCGIFQARLAGEALLDSGVRVTAVFASPALRCVQTAKHILEELKLEKKLKIRVEPGIFEWMKWEASKATLTFLTLEELKEANFNVDLDYRPALPRCSLMP--AESYDQYVERCAVSMGQIINTCPQDMGITLIVSHSSALDSCTRPLLGLPPRECGDFAQLVRKIPSLGMCFCEENREDGKWDLVNPPVKTLTHGANSVFNWRNWISSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L9L6-1", "uniprot_id": "A0ABK0L9L6_RAT", "id": "A0ABK0L9L6-1", "name": "Ubiquitin-associated and SH3 domain-containing protein A", "aln": "MSALASSPPVSRRLVYGKQEGMAAGETQLYAKVSNKLKGRSTS------SLLDPLLALGFPTHTALKALAATGMKTAEEAADWLHGHCSDPSLDDPIPQEYALFLCPTGPLLEKLQEFWRESRRQCAKNKAHEVFPHVTLCDFFTCEDQKVECLYEALRRAGDRILGSFPALVPLVLHSSISYLGFFINDSPADVIRDFAMAFATEAS--ALAD--------------------------------------CTIKPCTKQLHLTLAHKFYPHHQRTLEQLARAIQPSHTCQWTAALYSRDMRFVHYQTLKALFQYKPQNADELMLSPGDYIFVDPTQQEEASEGWAIGISHRTGCRGFLPENYTERANEADTWVKHRTYTFSLAMDLNSR----------------------------KEFE-----ASSRRNGDSHTPSVSRSISDIQALQATIA-------------------------------------------------------------------RRGVLVIRHGERVDQVFGKSWLHQCTTTDGKYYRPDLNFPRSLPRRSNGIKDFENDPPLSSCGIFQARLAGEALLDSGVRVTAVFASPALRCVQTAKHILEELKLERRLKIKVEPGIFEWMKWEAGKATLTFLTLEELKEADFNVDLDYRPAFPCCSLLP--AESYDQYVERCAVSMGQIINTCPQDMGITLIVSHSSALDSCTRPLLGLPPRECGDFAQLVRKIPSLGMCFCEENKEDGKWDLVNPPVKTLTHGANSVFNWRNWISSN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57075-1", "uniprot_id": "UBS3A_HUMAN", "id": "P57075-1", "name": "Ubiquitin-associated and SH3 domain-containing protein A", "aln": "---------------------MAAGETQLYAKVSNKLKSRSSP------SLLEPLLAMGFPVHTALKALAATGRKTAEEALAWLHDHCNDPSLDDPIPQEYALFLCPTGPLLEKLQEFWRESKRQCAKNRAHEVFPHVTLCDFFTCEDQKVECLYEALKRAGDRLLGSFPTAVPLALHSSISYLGFFVSGSPADVIREFAMTFATEAS--LLAGTSVSRFWIFSQVPGHGPNLRLSNLTRASFVSHYILQKYCSVKPCTKQLHLTLAHKFYPHHQRTLEQLARAIPLGHSCQWTAALYSRDMRFVHYQTLRALFQYKPQNVDELTLSPGDYIFVDPTQQDEASEGWVIGISQRTGCRGFLPENYTDRASESDTWVKHRMYTFSLATDLNSR----------------------------KDGE-----ASSRCSG-EFLPQTARSLSSLQALQATVA-------------------------------------------------------------------RKSVLVVRHGERVDQIFGKAWLQQCSTPDGKYYRPDLNFPCSLPRRSRGIKDFENDPPLSSCGIFQSRIAGDALLDSGIRISSVFASPALRCVQTAKLILEELKLEKKIKIRVEPGIFEWTKWEAGKTTPTLMSLEELKEANFNIDTDYRPAFPLSALMP--AESYQEYMDRCTASMVQIVNTCPQDTGVILIVSHGSTLDSCTRPLLGLPPRECGDFAQLVRKIPSLGMCFCEENKEEGKWELVNPPVKTLTHGANAAFNWRNWISGN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BGG7-1", "uniprot_id": "UBS3B_MOUSE", "id": "Q8BGG7-1", "name": "Ubiquitin-associated and SH3 domain-containing protein B", "aln": "----------------------MAAREELYSKVTPRRDRLQRPGTVKHGSALDVLLSMGFPRARAQKALASTGGRSVQAACDWLFSHVGDPFLDDPLPREYVLYLRPTGPLAQKLSDFWQQSKQICGKNKAHNIFPHITLCQFFMCEDSKVDALGEALQTTVSRWKCKFSAPLPLELYTSSNFIGLFVKEDSAEVLKKFAADFAAEAA--SKTE--------------------------------------VHVEPHKKQLHVTLAYHFQASHLPTLEKLAQNIDVKLGCDWVATIFSRDIRFANHETLQVIYPYSPQNDDELELVPGDFIFMSPMEQTSTSEGWIYGTSLTTGCSGLLPENYITKADECSTWIFHGSYSILNTVSSSSL----------------------------AFGDGALERRQYEDQGLGETTPLTIICQPMQPLRVNSQPGPQ---------------------------------------------------------------KRCLFVCRHGERMDVVFGKYWLSQCFDAKGRYIRTNLNMPHSLPQRSGGFRDYEKDAPITVFGCMQARLVGEALLESNTVIDHVYCSPSLRCVQTAHNILKGLQQDNHLKIRVEPGLFEWTKWVAGSTLPAWIPPSELAAANLSVDTTYRPHIPVSKLAI--SESYDTYINRSFQVTKEIISECKSKGNNILIVAHASSLEACTCQLQGLSPQNSKDFVQMVRKIPYLGFCSCEELGETGIWQLTDPPILPLTHGPTGGFNWRETLLQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TF42-1", "uniprot_id": "UBS3B_HUMAN", "id": "Q8TF42-1", "name": "Ubiquitin-associated and SH3 domain-containing protein B", "aln": "-----------MAQYGHPSPLGMAAREELYSKVTPRRNRQQRPGTIKHGSALDVLLSMGFPRARAQKALASTGGRSVQAACDWLFSHVGDPFLDDPLPREYVLYLRPTGPLAQKLSDFWQQSKQICGKNKAHNIFPHITLCQFFMCEDSKVDALGEALQTTVSRWKCKFSAPLPLELYTSSNFIGLFVKEDSAEVLKKFAADFAAEAA--SKTE--------------------------------------VHVEPHKKQLHVTLAYHFQASHLPTLEKLAQNIDVKLGCDWVATIFSRDIRFANHETLQVIYPYTPQNDDELELVPGDFIFMSPMEQTSTSEGWIYGTSLTTGCSGLLPENYITKADECSTWIFHGSYSILNTSSSNSL----------------------------TFGDGVLERRPYEDQGLGETTPLTIICQPMQPLRVNSQPGPQ---------------------------------------------------------------KRCLFVCRHGERMDVVFGKYWLSQCFDAKGRYIRTNLNMPHSLPQRSGGFRDYEKDAPITVFGCMQARLVGEALLESNTIIDHVYCSPSLRCVQTAHNILKGLQQENHLKIRVEPGLFEWTKWVAGSTLPAWIPPSELAAANLSVDTTYRPHIPISKLVV--SESYDTYISRSFQVTKEIISECKSKGNNILIVAHASSLEACTCQLQGLSPQNSKDFVQMVRKIPYLGFCSCEELGETGIWQLTDPPILPLTHGPTGGFNWRETLLQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5YC04-1", "uniprot_id": "A0A8I5YC04_RAT", "id": "A0A8I5YC04-1", "name": "", "aln": "------------------------MGFSLPSKFTPLFQR--------------------------QKALASTGGRSVQAACDWLFSHVGDPFLDDPLPREYVLYLRPTGPLAQKLSDFWQQSKQICGKNKAHNIFPHITLCQFFMCEDSKVDALGEALQTTVSRWRCKFSAPLPLELYTSSNFIGLFVKEDSAEVLKKFAADFAAEAA--SKTE--------------------------------------VHVEPHKKQLHVTLAYHFQASHLPTLEKLAQNIDVKLGCDWVATIFSRDIRFANHETLQVIYPYSPQNDDELELVPGDFIFMSPMEQTSTSEGWIYGTSLTTGCSGLLPENYITKADECSTWIFHGSCSILNTVSSSAL----------------------------AFGDGALERRQYEDQGLGETTPLTIICQPMQPLRVNSQPGPQ---------------------------------------------------------------KRCLFVCRHGERMDVVFGKYWLSQCFDAKGRYIRTNLNMPHSLPQRSGSFRDYEKDAPITVFGCMQARLVGEALLESNTVIDHVYCSPSLRCVQTAHNILKGLQQDNHLKIRVEPGLFEWTKWVAGSTLPAWMPPSELAAANLSVDTTYRPHIPVSKLVI--SESYDTYINRSFQVTKEIISECKSKGNNILIVAHASSLEACTCQLQGLSPQNSKDFVQMVRKIPYLGFCSCEELGETGIWQLTDPPILPLTHGPTGGFNWRETLLQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VCE9-1", "uniprot_id": "EPP_DROME", "id": "Q9VCE9-1", "name": "Ecdysteroid-phosphate phosphatase", "aln": "------------------MATLPPRKSQTPTRICISKQHLTP---------LQTLLQMGFPRHRAEKALASTGNRGVQIASDWLLAHVNDGTLDECAPREYIIYACPTGPFLQQLEEFWAKSRQMCGWNGAHNYVPHITLVSFFKAPDECSLQLSKALKQVVDMTGALLDRPLKLEPYMSQNFMGFFVAEEDANYLKRLALQYVKEVSNSIISDTYEQLDAIVACFPWCG-------AVSSGTRCIPRSSRSISLEPHVKSLHLTLAYQFPQAQFNALKALVETLDASCASNWELRLYSRDPRLATKQVQKVVYPHNPHETDELELRIGDYIYLNTEVVDSSSDGWAEGISWLTGSTGHLPVNYTERTAESDAWTLHRVVQLSKSVASSLTSAEDLDIVDGRSISTEPDDRQNTAHPDIIEGSSFEESEQSVEKYLRQTLKPCLELPSVQLLNSHNLTHQHNPNTPTIEITTNMSSSSTSMSKQPVDEILVEPPAAQPPRPDDTLSVHSDHSLHPGSLDASHAKNRKIYIMRHGERVDFTFG-TWIPYCFDEFGNYMRKDLNMPKTLPRRKNSPEGWQNDSPLTNVGVYQANLIGQALLEAQVQIDHVYCSPSYRCIQTCTSALEGLKLTGKQKIKLEPGLFEWMAWYP-SGVPDWLTKNELTEAKFDVDLDYEPVQPASELTARLKESTEQFYERNHDVILQLL---EQTTGNILVVAHATTLDTCSRQLTGGVPRSTNELRQVIHKIPYCSLATVEQ--VDGVWKLVEPECLPVTHSKNPRFEWNALSAT-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53929-1", "uniprot_id": "YNK8_YEAST", "id": "P53929-1", "name": "Uncharacterized protein YNL108C", "aln": "------------------------------------------------------------------MAIENIYIARHGYRSNWLP---KGPYPPPPTGIDNDVPLSEHG---------VEQAHELANYISKLDVKPEMIFSSPFYRCLETSKPTVEALK------------------------IPLYVDRGVGEWYKPDRPIIPEPAT---------------------------------------------------------------------HEVMSKFFPSMISPDWEPSIIPSNKGETEEDIFERCHKFWPVFIDRVERKFPNVKTIMIVTHAATKSALGMNLLKFSSAK--------EPIDNKGTFIRNGSCAIDK------------------------------------------------------------------------------------------------------------------------------------------------FELVKGENESIPFEEREWKLTMNGNTSFLTNGEEMNWTFMN------------------AFEAG---------------------------SDADIKARRAAESGKLKME-----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: ** . : : * :::. . : *.: : . * . :**: : ::: .: : .: : : . : :* : . : . : . . . * *.: : : :... . :.. : .:: : : :**. . * : . :: :: . :: . :: : *:::* ", "identical_positions": 16, "similar_positions": 76, "identity": "2.02%" }, { "cls_id": "homologset.agr.SGD:S000005054", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91VE6-1", "uniprot_id": "MK67I_MOUSE", "id": "Q91VE6-1", "name": "MKI67 FHA domain-interacting nucleolar phosphoprotein", "aln": "-MAGLAG---PAKPSLALNPQEDSQFEKALT--QIQGRTKKPQQKKKEKLN--------------------------------------RGVVYLGHLPSTLSESHIYNYCAQFGDISRFRLSRSKRTGNSKGYAFVEFESEDVAKIVAETMDNYLFGERLLSCKFMPRKKVHKDLFSQ-------------RNALFHRPSFPAVKRYNRKRGHLQMLKMEYRFKKKEKLLRKKLAAKGIDYS--FPSLVLPKPKNIAVAHRDSEGNQVLPDQKEGLSGEPRRKEKMMKEDISNNIPKKRKRSRRKKSSVDSQGPTPVCTPTFLERRKSQVMEVGGD-KDDEIILKLPVPPVKEDTQKTPTSASPGGKRPRKRKSKQ--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5RJM0-1", "uniprot_id": "MK67I_RAT", "id": "Q5RJM0-1", "name": "MKI67 FHA domain-interacting nucleolar phosphoprotein", "aln": "-MAEYSG---PAKPTLALNPREDSQFEKDLT--QIQRRAKK---KKEEKLN--------------------------------------SGVVYLGHLPSTLSESHIYDYCAQFGDIRRFRLSRSKRTGNSRGFAFVEFESEDVAKIVAETMDNYLFGERLLSCKFMPREKVHKDLFNQ-------------CNVPFHPPSFPAVKRYNQKRGHLQMLKMEYRFKKKEKLLRKKLAKKGIDYS--FPSLVLPKPKKEISSIANTHGD-----------------------------------------SEANQDPTPVCTPTFLERRKSQLMEIN---DDDEIILKLPVSPVKEDTQKTPAPESSGKKRLRKRKSKQ--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BYG3-1", "uniprot_id": "MK67I_HUMAN", "id": "Q9BYG3-1", "name": "MKI67 FHA domain-interacting nucleolar phosphoprotein", "aln": "-MATFSG---PAGPILSLNPQEDVEFQKEVA--QVRKRITQ--RKKQEQLT--------------------------------------PGVVYVRHLPNLLDETQIFSYFSQFGTVTRFRLSRSKRTGNSKGYAFVEFESEDVAKIVAETMNNYLFGERLLECHFMPPEKVHKELFKD-------------WNIPFKQPSYPSVKRYNRNRTLTQKLRMEERFKKKERLLRKKLAKKGIDYD--FPSLILQKTESISKTNRQTSTKGQVLRKKK---------------------KKVSGTLDTPEKTVDSQGPTPVCTPTFLERRKSQVAELNDDDKDDEIVFKQPISCVKEEIQETQTPTHSRKKR--RRSSNQ--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JIY8-1", "uniprot_id": "MK67I_DANRE", "id": "Q8JIY8-1", "name": "MKI67 FHA domain-interacting nucleolar phosphoprotein", "aln": "-MTEGKSSDKPAKRLLALNPKEDAEFQKKVQ--QVKKRPQT-----GQTLS--------------------------------------PGVLYVGHLPRGLFEPQLKSYFEQFGKVLRLRVSRSKKTGGSKGYGFVEFECDEVAKIVAETMNNYLMGERIIKCHVIPPEKVHEKLFVG-------------SIAGFKKPKYPAVTRYNKTHTEDDVKKVGTKLLSKESKLRKRLAAKGIDYD--FPGFAAQIPAKKAPSEAN--------------------------------------------VSVCSEDVTPVCTPSLLERRKS--LRVEDDDVDDEIVIKVKPLPENSDDVEESEEESAEEDEGEEEEAA---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCY1-1", "uniprot_id": "Q9VCY1_DROME", "id": "Q9VCY1-1", "name": "RRM domain-containing protein", "aln": "-MPPVKKP-KAQKIEKQSTPKKPIDAAKNVVSGQLKKKVTKARPQKPKGPE--------------------------------------RGVVIVKHLPHGFFEQQLRQYFRQFGRVLRVRLARSLRTGNSKGYAFVEFEYPEVAKVAADTMDNYLMFQKVVKATYIPPEKQTLNFFRTSLKKVVNKAGKEIYVSDLTKATQRSVKKQN-NWDESACQKRTVANLNKIKKLQEKYKDLGIDFSNLLVEPVKKAAGSAEASTSQAAAKKAGKKQKTAAKKEPTLEDLLGNTINEDSDDEDYVDASDDESDLEAEEEQADSEQTSDDSDEEEDLSPPPKQKKTKLADKLKRKPGTGGVQKKKIAPPAKSNKNAATQKLQLAAAKSLAKPLPKGKAKKSK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53927-1", "uniprot_id": "NOP15_YEAST", "id": "P53927-1", "name": "Ribosome biogenesis protein 15", "aln": "MVKSTSKTSTKETVTKQPTEEKPIQEKEELALETSSSSSDEEDEKDEDEIEGLAASDDEQSGTHKIKRLNPKKQANEKKSKDKKTLEEYSGIIYVSRLPHGFHEKELSKYFAQFGDLKEVRLARNKKTGNSRHYGFLEFVNKEDAMIAQESMNNYLLMGHLLQVRVLPKGAKIEKLYKY------------------------KKRVLVEKGITKPVKQLKDNMKQKHEERIKKLAKSGIEFKW---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .: : : : . *:: : :** : * .: .* *** : ..*::*. :**.*: :.*:** : * :. ::*:***: :::. :* .:: . : .* :: **::. ", "identical_positions": 25, "similar_positions": 51, "identity": "6.3%" }, { "cls_id": "homologset.agr.SGD:S000005055", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04166-1", "uniprot_id": "CYB5B_RAT", "id": "P04166-1", "name": "Cytochrome b5 type B", "aln": "----MATPEASGSGRNGQGSDPAVTYYRLEEVAKRN--TAEETWMVIHGRVYDITRFLSEHPGGEEVLLEQAGADATESFEDVGHSPDAREMLKQYYIGDVHPNDLKPKDGDKD---PSKNNSCQSSWAYWIVPIVGAILIGFLYRHFWADSKSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQX2-1", "uniprot_id": "CYB5B_MOUSE", "id": "Q9CQX2-1", "name": "Cytochrome b5 type B", "aln": "----MATPEASGSGEKVEGSEPSVTYYRLEEVAKRN--SAEETWMVIHGRVYDITRFLSEHPGGEEVLLEQAGADATESFEDVGHSPDAREMLKQYYIGDVHPSDLKPKGDDKD---PSKNNSCQSSWAYWFVPIVGAILIGFLYRHFWADSKSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43169-1", "uniprot_id": "CYB5B_HUMAN", "id": "O43169-1", "name": "Cytochrome b5 type B", "aln": "MSGSMATAEASGSDGKGQEVETSVTYYRLEEVAKRN--SLKELWLVIHGRVYDVTRFLNEHPGGEEVLLEQAGVDASESFEDVGHSSDAREMLKQYYIGDIHPSDLKPESGSKD---PSKNDTCKSCWAYWILPIIGAVLLGFLYRYYTSESKSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56395-1", "uniprot_id": "CYB5_MOUSE", "id": "P56395-1", "name": "Cytochrome b5", "aln": "---------------MAGQSDKDVKYYTLEEIQKHK--DSKSTWVILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDARELSKTYIIGELHPDDRSKIAKPSD-TLITTVESNSSWWTNWVIPAISALAVALMYRLYMAED---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00173-1", "uniprot_id": "CYB5_RAT", "id": "P00173-1", "name": "Cytochrome b5", "aln": "---------------MAEQSDKDVKYYTLEEIQKHK--DSKSTWVILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDARELSKTYIIGELHPDDRSKIAKPSE-TLITTVESNSSWWTNWVIPAISALVVALMYRLYMAED---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00167-1", "uniprot_id": "CYB5_HUMAN", "id": "P00167-1", "name": "Cytochrome b5", "aln": "---------------MAEQSDEAVKYYTLEEIQKHN--HSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPE-TLITTIDSSSSWWTNWVIPAISAVAVALMYRLYMAED---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V4N3-1", "uniprot_id": "CYB5_DROME", "id": "Q9V4N3-1", "name": "Cytochrome b5", "aln": "------------------MSSEETKTFTRAEVAKHN--TNKDTWLLIHNNIYDVTAFLNEHPGGEEVLIEQAGKDATENFEDVGHSNDARDMMKKYKIGELVESERTSVAQKSEPTWSTEQQTEESSVKSWLVPLVLCLVATLFYKFFFGGAKQ-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40312-1", "uniprot_id": "CYB5_YEAST", "id": "P40312-1", "name": "Cytochrome b5", "aln": "----------------------MPKVYSYQEVAEHN--GPENFWIIIDDKVYDVSQFKDEHPGGDEIIMDLGGQDATESFVDIGHSDEALRLLKGLYIGDVDKTSERVSVEKVS-----TSENQSKGSGTL-VVILAILMLGVAYYLLNE-----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8IRR0-1", "uniprot_id": "Q8IRR0_DROME", "id": "Q8IRR0-1", "name": "Cytochrome b5", "aln": "----------------------MSKEIRLATVNEHN--KATDLWVVIDNKVYDVTKFRLEHPGGEESLVDEAGRDATKAFNDVGHSSEAREMLKKYYIGDLAAADIKKKSPISC-----RHVALALGAAFIGISLVYVIRRGVARN---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VUZ3-1", "uniprot_id": "Q9VUZ3_DROME", "id": "Q9VUZ3-1", "name": "Cytochrome b5 heme-binding domain-containing protein", "aln": "----------------------MSQLYELSEVAQQNGKNGKPCWLIIKGNVYDVTKFLGEHPGGSEALLEYGGKDATKAFKQAGHSSDAEKDLKNYKIGEINSAAPIQVQPTSN-----GAAKPTANTISEDPEPAKNSSSGFCCC---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::: *:::. .:**:: * *****.* : : .* **:: * : *** :* * **:: . ", "identical_positions": 21, "similar_positions": 23, "identity": "13.55%" }, { "cls_id": "homologset.agr.SGD:S000005056", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17844-1", "uniprot_id": "DDX5_HUMAN", "id": "P17844-1", "name": "Probable ATP-dependent RNA helicase DDX5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MSGYSSD-RDRGRDRGFGAPR---FGGSRAGP------------------------------------------------------LSGKKFGNPGEKLVKKKWNLDE--LPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRG-HNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACR--LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKE-----NKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVE--------------------DRGSG---------------------RSRGRGG--------MKDDRRDRYSAGKRGG----------------------FNTFRDRENYDRG-YSS-------------------LLKRDFGAKTQNGVYSAANYTNGSFGSNFVSAG-------IQTS--FRTGNPTGTYQNGYDSTQQYGSNVPNMHNGMNQQAYAYPAT-AAAPMIGYPMPTGYSQ--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61656-1", "uniprot_id": "DDX5_MOUSE", "id": "Q61656-1", "name": "Probable ATP-dependent RNA helicase DDX5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MSSYSSD-RDRGRDRGFGAPR---FGGSRTGP------------------------------------------------------LSGKKFGNPGEKLVKKKWNLDE--LPKFEKNFYQEHPDLARRTAQEVDTYRRSKEITVRG-HNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACR--LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKE-----NKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVE--------------------DRGSG---------------------RSRGRGG--------MKDDRRDRYSAGKRGG----------------------FNTFRDRENYDRG-YSN-------------------LLKRDFGAKTQNGVYSAANYTNGSFGSNFVSAG-------IQTS--FRTGNPTGTYQNGYDSTQQYGSNVANMHNGMNQQAYAYPLP-QAAPMIGYPMPTGYSQ--------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G4Y3-1", "uniprot_id": "A0A8I6G4Y3_RAT", "id": "A0A8I6G4Y3-1", "name": "Probable ATP-dependent RNA helicase DDX5", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------GAPGVPREYKGRFRGRLFGAPR---FGGSRTGP------------------------------------------------------LSGKKFGNPGEKLVKKKWNLDE--LPKFEKNFYQEHPDLARRTAQEVDTYRRSKEITVRG-HNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACR--LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKE-----NKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVE--------------------DRGSG---------------------RSRGRGG--------MKDDRRDRYSAGKRGG----------------------FNTFRDRENYDRG-YSS-------------------LLKRDFGAKTQNGVYSAANYTNGSFGSNFVSAG-------IQTS--FRTGNPTGTYQNGYDSTQQYGSNVANMHNGMNQQAYAYPATAAAAPMIGYPMPTGYSQ--------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q501J6-1", "uniprot_id": "DDX17_MOUSE", "id": "Q501J6-1", "name": "Probable ATP-dependent RNA helicase DDX17", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MRGGGFGDRDRDRDRGG-------FGARGGSG------------------------------------------------------LPPKKFGNPGERLRKKKWDLSE--LPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSR--LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKE-----NKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVD--------------------HRGGGGGGG----------------GRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGR------------------RDSTSYRDRSETDRASYANGSGY--------------GSPNSAFGAQAGQYTYAQGTYGAAAYGTSGYTAQ-------EYAAGTYGASSTASAGRSSQSSSQQFSGIGRSGQQPQPLMSQQFAQPPGATNMIGYMGQTAYQYPPPPPPPPPSRK--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92841-4", "uniprot_id": "DDX17_HUMAN", "id": "Q92841-4", "name": "Probable ATP-dependent RNA helicase DDX17", "aln": "--------------------------------------------------------MPTGFVAPILCVLLPSP-----TREAATVASATGDSASERESAAPAAAPTAEAPPPSVVTRPEPQALP--------------SPAIRAPLPDLYPFG---TMRGGGFGDRDRDRDRGG-------FGARGGGG------------------------------------------------------LPPKKFGNPGERLRKKKWDLSE--LPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSR--LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKE-----NKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVD--------------------HRGGGGGGG----------------GRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGR------------------RDSASYRDRSETDRAGYANGSGY--------------GSPNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQ-------EYGAGTYGASSTTSTGRSSQSSSQQFSGIGRSGQQPQPLMSQQFAQPPGATNMIGYMGQTAYQYPPPPPPPPPSRK--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9PT29-1", "uniprot_id": "E9PT29_RAT", "id": "E9PT29-1", "name": "RNA helicase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MRGGGFGDRDRDRDRGG-------FGARGGSG------------------------------------------------------LPPKKFGNPGERLRKKKWDLSE--LPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSR--LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKE-----NKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVD--------------------HRGGGGGGGKG--------------GRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGR------------------RDSTSYRDRSETDRASYANGSGY--------------GSPNSAFGAQAGQYTYAQGTYGAAAYGTSGYTAQ-------EYAAGTYGASSTTSTGRSSQSSSQQFSGIGRSGQQPQPLMSQQFAQPPGATNMIGYMGQTAYQYPPPPPPPPPSRK--------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W3M7-1", "uniprot_id": "Q9W3M7_DROME", "id": "Q9W3M7-1", "name": "RNA helicase", "aln": "--------------------------------------------------------MFAGAYAPNAGGVQQHTGGGYYGNGAAAGAGGSGNGAPRHERQYYPRGNFGGAAGGAGINGAATAAGS--------------MHFGQPYGVMTYGIQNGLGMGAAGSGGGNPYRQQNGVAFAGNGLGGGAGGGSGGSGGYGGQRGKNPTYAQRYQKPNNGAGVAGGYQSNNYNAAALGMLSKEERAEIQREKAKNPGRNLVKPKWEN----LEPFLKDFYNIHPNTLAKSEQQVAEIRRELEITVSG-NELPHPVVSFEESSLPAHVIEEMKRQGFTKPTAIQSQGWPIALSGRDLVGIAQTGSGKTLAYMLPAIVHIGNQPPIIRGEGPIALVLAPTRELAQQIQSVVRDYGHLCKPEIRHTCIFGGSSKVPQARDLDRGVEVIIATPGRLIDFLENRNTNLQRCTYLVLDEADRMLDMGFEPQIRKIIEQIRPDRQVVMWSATWPKEVQALAGDFLNDYIQINIGSMNLSANHNIRQIVEICTEIEKPQRLVCLLNEISPIKNSGNNGNKIIVFVETKIKVEDILQIIRAEGYNATSIHGDKTQNERDSVLKDFRNGKSNILIATDVASRGLDVEDLQYVINYDYPNSSENYVHRIGRTGRCQQLGTAYTFFTPDNAKQARELISVLEEAGQTPSQALLDLARSMPSSGGYRGNKRWNNNSGGDRNTGGNNGIYQQRNNNPLNYQAGNNYNNNRSGPPTGSSYQQYAAGGNTYLQNGAGGGVNWNRMNQMGQDGGAGQQQRNGNTYRPRAPFNNGGPRAIMGHQGGGVGAGGAAGVGGGPQQLMAPQQGGQYMPQAYRGRSQFVPQGAGAGGMPPRFQQYPKREYQQQGVTHYGQQALQHQQQQQQAGQQTKPPKDESNKYVPSAAVTSSLVQYTPANSPTIAAVAAAAAAAAGRAAAAAVAPAPGAAYMYDAAGVLTTAAAPGTNPYANQFSMPATYYAAQHHQFAQAVAGPGPAPGQAIE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24783-1", "uniprot_id": "DBP2_YEAST", "id": "P24783-1", "name": "ATP-dependent RNA helicase DBP2", "aln": "--------------------------------------------------------------------------------------MTYGGRDQQYNKTNYKS------------------------------------------------------------RGGDFRGGRNSDRNS---YNDRPQGGNYR-------------------------------------------------GGFGGRSNYNQPQELIKPNWDEELPKLPTFEKNFYVEHESVRDRSDSEIAQFRKENEMTISG-HDIPKPITTFDEAGFPDYVLNEVKAEGFDKPTGIQCQGWPMALSGRDMVGIAATGSGKTLSYCLPGIVHINAQPLLAPGDGPIVLVLAPTRELAVQIQTECSKFGHSSR--IRNTCVYGGVPKSQQIRDLSRGSEIVIATPGRLIDMLEIGKTNLKRVTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVKQLAADYLNDPIQVQVGSLELSASHNITQIVEVVSDFEKRDRLNKYLETASQDNE-----YKTLIFASTKRMCDDITKYLREDGWPALAIHGDKDQRERDWVLQEFRNGRSPIMVATDVAARGIDVKGINYVINYDMPGNIEDYVHRIGRTGRAGATGTAISFFTEQNKGLGAKLISIMREANQNIPPELLKYDR-----------------------------------------------------------------------------------------------------------------------------------------RS---YGGGHPRYGGGRGGRGGYGRRGGYGG-----------------GRGGYGG-NRQRDGGWGNRGRSNY--------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P19109-1", "uniprot_id": "DDX17_DROME", "id": "P19109-1", "name": "ATP-dependent RNA helicase p62", "aln": "MLKLVQYIAPRVGGATPRPTACGWGNLLLISPRSGASSEKCITQRRHFLFSSASSSGTFASSSSLCTEQRQQFHGSRRNRETILFPSTYSSLQAQSQRAFRDSSKPDSDDYVDSIPKAEQRTRTRKSLFNDPDERTEEIKIEGVMAPHDRDFGHSGRGGRGGDRGGDDRRGGGGGGNR---FGGGGGGGDYHGIRNGRVEKRRDDRGGGNRFGGG--------------------------GGFGDRRGGGGGGSQDLPMRPVDFSNLAPFKKNFYQEHPNVANRSPYEVQRYREEQEITVRG--QVPNPIQDFSEVHLPDYVMKEIRRQGYKAPTAIQAQGWPIAMSGSNFVGIAKTGSGKTLGYILPAIVHINNQQPLQRGDGPIALVLAPTRELAQQIQQVATEFGSSSY--VRNTCVFGGAPKGGQMRDLQRGCEIVIATPGRLIDFLSAGSTNLKRCTYLVLDEADRMLDMGFEPQIRKIVSQIRPDRQTLMWSATWPKEVKQLAEDFLGNYIQINIGSLELSANHNIRQVVDVCDEFSKEEKLKTLLSDIYDTSESP---GKIIIFVETKRRVDNLVRFIRSFGVRCGAIHGDKSQSERDFVLREFRSGKSNILVATDVAARGLDVDGIKYVINFDYPQNSEDYIHRIGRTGRSNTKGTSFAFFTKNNAKQAKALVDVLREANQEINPALENLAR-----------------------------------------------------------------------------------------------------------------------------------------NSRYDGGGGRSRYGGGGGG-GRFGG-GGFKK-----------------GSLSNGR-GFGGGGGGGGEGRHSRFD------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : . . * * *:** * . : :: *.. *:*: * *:*: * . :* *:. : : : ** **.**:*:*:** ::**:* *******.* **.****. * : *:*** ********** *:* .: . :: **::** .* * ***.** *: *********:*. .***:* ***********************:.*******.:**********: ** *:* : ::::* ::***.*** *:*:: : .* .:* :. .: * ::*..** ::: : :* * . ***** * *** **.:*: *:: *::*****:**:**..:::***:* * . *:*:******.*. **: :*** * *:.::.**.* * . . . . : . ", "identical_positions": 194, "similar_positions": 120, "identity": "19.02%" }, { "cls_id": "homologset.agr.SGD:S000005057", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AK96-1", "uniprot_id": "A0A8I6AK96_RAT", "id": "A0A8I6AK96-1", "name": "DNA-directed RNA polymerases I and III subunit RPAC2", "aln": "---------------------MEDDQELERKISGLKTSMAEGERKTALEMVQAAGTDRQCVTFVLHEEDHTLGNCLRYIIMKNPEVEFCGYTTTHPSESKINLRIQTRGALPAVEPFQKGLNELLNVCQHVLVKFEASVKDYKDKKASKNEPTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97304-1", "uniprot_id": "RPAC2_MOUSE", "id": "P97304-1", "name": "DNA-directed RNA polymerases I and III subunit RPAC2", "aln": "---------------------MEDDQELERKISGLKTSMAEGERKTALEMVQAAGTDRQCVTFVLHEEDHTLGNCLRYIIMKNPEVEFCGYTTTHPSESKINLRIQTRGALPAVEPFQKGLNELLNVCQHVLVKFEASIKDYKAKKASKKEPTF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DPB6-1", "uniprot_id": "RPAC2_HUMAN", "id": "P0DPB6-1", "name": "DNA-directed RNA polymerases I and III subunit RPAC2", "aln": "---------------------MEEDQELERKISGLKTSMAEGERKTALEMVQAAGTDRHCVTFVLHEEDHTLGNSLRYMIMKNPEVEFCGYTTTHPSESKINLRIQTRGTLPAVEPFQRGLNELMNVCQHVLDKFEASIKDYKDQKASRNESTF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DRI4-1", "uniprot_id": "RPAC2_DANRE", "id": "Q6DRI4-1", "name": "DNA-directed RNA polymerases I and III subunit RPAC2", "aln": "--------------------------------------MAELGQKHALEMVRTDGADEGCVTFVLNEEDHTLGNSLRYMIMKSQDVEFCGYSITHPSESKINFRIQTRDGVPASEPLRNGLNNLTDVCKHVLQTFEARMKEFKEQEESMT----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P28000-1", "uniprot_id": "RPAC2_YEAST", "id": "P28000-1", "name": "DNA-directed RNA polymerases I and III subunit RPAC2", "aln": "MTEDIEQKKTATEVTPQEPKHIQEEEEQDVDMTGDEEQEEEPDREKIKLLTQATSEDGTSASFQIVEEDHTLGNALRYVIMKNPDVEFCGYSIPHPSENLLNIRIQTYGETTAVDALQKGLKDLMDLCDVVESKFTEKIKSM------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VIZ0-1", "uniprot_id": "RPAC2_DROME", "id": "Q9VIZ0-1", "name": "DNA-directed RNA polymerases I and III subunit RPAC2", "aln": "-------------------------------------------MGALAELAGDEKNGEGSRTFVFTNEGHTLGNALKTIIARYPEVDFCGYTIPHPTEQKLHFRIQSRRDR-AIDILKRGLEDLEGLCDHTIVTFEKEMAEFNAMKVEN-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . . :* : :*.*****.*: :* : :*:****: .**:*. :::***: * : ::.**::* .:*. . .* : . ", "identical_positions": 26, "similar_positions": 35, "identity": "16.88%" }, { "cls_id": "homologset.agr.SGD:S000005062", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MK19-1", "uniprot_id": "A0A096MK19_RAT", "id": "A0A096MK19-1", "name": "m7GpppN-mRNA hydrolase", "aln": "------METKRLEIPGSVLDDLCSRFILHIPSEERDNAIRVCFQIELAHWFYLDFYMQNTPGLPQCGIRDFAKAVFSHCPFLLPQGEDVEKILDEWKEYKMGVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGVPKDTKFNPKTRREIRNIEWFSIEKLP------------------------CHRNDMTPKSKLGLAPNKFFMAIP------FIRPLRDWLSRRFGDSSD-SDNGFSSAGSTPARPTVEKLSRTKFRHSQQLFPEGSPSDQWVKHRQPLQQK-HSNHTEVSDLCKAKN------------------------------------------------------------------------------------------------QNMRGNGRKQYQDSPNQKKRVNGIHGQPTKQQNP---------------------------------------------------------------------------LMKCEKKLHPRKLQDNFETDAACDLPCSGEDPLVEHAEGHSVACNG--------------------------------------------------------------------------------------------------HCKFPFSSRTFLSFKFDQNAIMKILDL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CYC6-1", "uniprot_id": "DCP2_MOUSE", "id": "Q9CYC6-1", "name": "m7GpppN-mRNA hydrolase", "aln": "------MEPKRLEIPGSVLDDLCSRFILHIPSEERDNAIRVCFQIELAHWFYLDFYMQNTPGLPQCGIRDFAKAVFSHCPFLLPQGEDVEKILDEWKEYKMGVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGVPKDTKFNPKTRREIRNIEWFSIEKLP------------------------CHRNDMTPKSKLGLAPNKFFMAIP------FIRPLRDWLSRRFGDSSD-SDNGFSSAGSTPARPTVEKLSRTKFRHSQQLFPEGSPSDQWVKHRQPLQQKSHSNHGEVSDLLKAKN------------------------------------------------------------------------------------------------QNMRGNGRKQYQDSPNQKKRANGVHGQPAKQQNP---------------------------------------------------------------------------LVKCEKKLHPRKLQDNFETDATCDLPCSGEEPSVEHAEGHSVACNG--------------------------------------------------------------------------------------------------HCKFPFSSRAFLSFKFDQNAIMKILDL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IU60-1", "uniprot_id": "DCP2_HUMAN", "id": "Q8IU60-1", "name": "m7GpppN-mRNA hydrolase", "aln": "------METKRVEIPGSVLDDLCSRFILHIPSEERDNAIRVCFQIELAHWFYLDFYMQNTPGLPQCGIRDFAKAVFSHCPFLLPQGEDVEKVLDEWKEYKMGVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLP------------------------CHRNDMTPKSKLGLAPNKFFMAIP------FIRPLRDWLSRRFGDSSD-SDNGFSSTGSTPAKPTVEKLSRTKFRHSQQLFPDGSPGDQWVKHRQPLQQKPYNNHSEMSDLLKGKN------------------------------------------------------------------------------------------------QSMRGNGRKQYQDSPNQKKRTNGLQ--PAKQQNS---------------------------------------------------------------------------LMKCEKKLHPRKLQDNFETDAVYDLPSSSEDQLLEHAEGQPVACNG--------------------------------------------------------------------------------------------------HCKFPFSSRAFLSFKFDHNAIMKILDL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53550-1", "uniprot_id": "DCP2_YEAST", "id": "P53550-1", "name": "m7GpppN-mRNA hydrolase", "aln": "MSLPLRHALENVTSVDRILEDLLVRFIINCPNEDLSSVERELFHFEEASWFYTDFIKLMNPTLPSLKIKSFAQLIIKLCPLVWKWDIRVDEALQQFSKYKKSIPVRGAAIFNENLSKILLVQGTESDS-WSFPRGKISKDENDIDCCIREVKEEIGFDLTDYIDDNQFIERNIQGKNYKIFLISGVSEVFNFKPQVRNEIDKIEWFDFKKISKTMYKSNIKYYLINSMMRPLSMWLRHQRQIKNEDQLKSYAEEQLKLLLGITKEEQIDPGRELLNMLHTAVQANSNNNAVSNGQVPSSQELQHLKEQSGEHNQQKDQQSSFSSQQQPSIFPSLSEPFANNKNVIPPTMPMANVFMSNPQLFATMNGQPFAPFPFMLPLTNNSNSANPIPTPVPPNFNAPPNPMAFGVPNMHNLSGPAVSQPFSLPPAPLPRDSGYSSSSPGQLLDILNSKKPDSNVQSSKKPKLKILQRGTDLNSIKQNNNDETAHSNSQALLDLLKKPTSSQKIHASKPDTSFLPNDSVSGIQDAEYEDFESSSDEEVETARDERNSLNVDIGVNVMPSEKDSRRSQKEKPRNDASKTNLNASAESNSVEWGPGKSSPSTQSKQNSSVGMQNKYRQEIHIGDSDAYEVFESSSDEEDGKKLEELEQTQDNSKLISQDILKENNFQDGEVPHRDMPTESNKSINETVGLSSTTNTVKKVPKVKILKRGETFASLANDKKAFDSSSNVSSSKDLLQMLRNPISSTVSSNQQSPKSQHLSGDEEIMMMLKRNSVSKPQNSEENASTSSINDANASELLGMLKQKEKDITAPKQPYNVDSYSQKNSAKGLLNILKKNDSTGYPRTEGGPSSEMSTSMKRNDATNNQELDKNSTELLNYLKPKPLNDGYENISNKDSSHELLNILHGNKNSSAFNNNVYATDGYSLASDNNENSSNKLLNMLQNRSSAINEPNFDVRSNGTSGSNELLSILHRK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: . :*:** ***:: *.*: ... * *::* * *** ** .* **. *:.**: ::. **:: . *:: *:::.:** .:*. ** *::*.*.::***** :.* *.**:**:.*:* **. *** ** ***:.*** .:::** .*:.: ::::*.*:.: :*:*:.*.** :****.::*:. *:.::. :.:* .:: : : * * *: *. . . *:*. * *..*: :::*.. . .*.** :.* ..* * .: . *: :: :. : :.. * ...*: * .* . . **:* :: .**. : : :. : : :* .*.*. :* . *:. ... : *: ..:* *: *::*: . :: ", "identical_positions": 114, "similar_positions": 166, "identity": "11.74%" }, { "cls_id": "homologset.agr.SGD:S000005063", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3B7U4-1", "uniprot_id": "CTU2_RAT", "id": "Q3B7U4-1", "name": "Cytoplasmic tRNA 2-thiolation protein 2", "aln": "MCQAGEDYAGPAQREPPPVPRPS------REQKCVKCAEGLP-VVVIR--AGDAFCRDCFKAFYVHKFRAMLGKNRVIFPGEKVLLSWSGGPSSSSMVWQVLEGLSQDSAKRLRFVPGVIYVDEGAACGQSLEDRVKTLAEVKRILGNTG--FPFHVVALEEVFSLPPSVLRRASQEPAGTEEAYKAAVDSFLQQQH-----VLGTEACASPAQGQGQLRPSHSQEPSGTVGHPKDAQTEALSRLFKSIKT-LTAKEELLQTLRTHLTVHVARSHGYRKVMTGESCTRLAIKLMTNLAMGRGA--FLAWDTGFSDERHG---DVVLVRPMRDHTLKEVAFYNRLFGVPSVFTP--AIDTKA-----------------PEKASIHRLMEAFILKLQTLFPSTVSTVYRTSEKL--VKAPREGCATGPSGPNCLLCMCALDVDNADSATAFGAQ-SSSHLSQMLT----AEAGTPTRPCCGAGEGQTQSCHRAVGRREDAWACIIEQLCYSCRVNMKDLPSLDPLPPYVLTEAQLRSQRGSVSEEIQEYLIEEEEEEDRAEPCEAMKQEAEDKGIGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U308-1", "uniprot_id": "CTU2_MOUSE", "id": "Q3U308-1", "name": "Cytoplasmic tRNA 2-thiolation protein 2", "aln": "MCQAGEDYAGPARREPPPVPRPS------REQKCVKCAEGLP-VVVIR--AGDAFCRVCFKAFYVHKFRAMLGKNRVIFPGEKVLLSWSGGPSSSSMVWQVLEGLSQDSAKRLRFVPGVIYVDEGAACGQSLEDRQKTVAEVKRILENTG--FPWHVVALEEVFSLPPSVLCCTSQESAGTEEAYKAAVDRFLQQQQQQQQRVLGAEAGASPAQGEARLHPSHGREPSGTAGYPTAAQTEALSRLFSSIKT-LTAKEELLQTLRTHLIVHIARVHGYCKVMTGETCTRLAIKLMTNLALGRGA--FLAWDTGFSDERHG---DVVLVRPMRDHTLKEVAFYNHLFRVPSVFTP--AIDTKA-----------------PEKASIHRLMEAFILRLQTLFPSTVSTVYRTSEKL--VKAPREGCAAGPSGPSCLLCMCALDIDTADSATAFGAQ-SSSHLSQMPS----AEAGMPTQPCCAAGEGQAQSCHREVGKRGDARACITEQLCYSCRVNMKDLPSLDPLPPYVLAEAQLRSQRGSVSEEIQEYLITDEEEDS-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2VPK5-1", "uniprot_id": "CTU2_HUMAN", "id": "Q2VPK5-1", "name": "Cytoplasmic tRNA 2-thiolation protein 2", "aln": "MCQVGEDYGEPAPEEPPPAPRPS------REQKCVKCKEAQP-VVVIR--AGDAFCRDCFKAFYVHKFRAMLGKNRLIFPGEKVLLAWSGGPSSSSMVWQVLEGLSQDSAKRLRFVAGVIFVDEGAACGQSLEERSKTLAEVKPILQATG--FPWHVVALEEVFSLPPSVLWCSAQELVGSEGAYKAAVDSFLQQQH-----VLGAGGGPGPTQGEEQP-PQPPLDPQNLARPPAPAQTEALSQLFCSVRT-LTAKEELLQTLRTHLILHMARAHGYSKVMTGDSCTRLAIKLMTNLALGRGA--FLAWDTGFSDERHG---DVVVVRPMRDHTLKEVAFYNRLFSVPSVFTP--AVDTKA-----------------PEKASIHRLMEAFILRLQTQFPSTVSTVYRTSEKL--VKGPRDGPAAGDSGPRCLLCMCALDVDAADSATAFGAQ-TSSRLSQMQSPIPLTETRTPPGPCCSPGVGWAQRCGQGACRREDPQACIEEQLCYSCRVNMKDLPSLDPLPPYILAEAQLRTQRAWGLQEIRDCLIEDSDDEAGQS----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DC53-1", "uniprot_id": "CTU2_DANRE", "id": "Q6DC53-1", "name": "Cytoplasmic tRNA 2-thiolation protein 2", "aln": "MCQVEEDYNGLECNQEK-IPVSG------LNRKCMKCKEGTA-VLIIR--VSDAFCRSCFKEYFIHKFRAMLGKNRVIFPQEKVLLAVSGGAASCTMLSQVQEGLSRDAPKKLRFMPGIVYIDDGGACGRSEDERQTSISQLKNIFTQTG--FPYFIVPLEKVFSLPTSVLVPGTSDPDPSNPCYKQAVDKYLKEKQ--------------KLREEEAVCAVAQLNLEDSAYLP--EHKLALQRLFSSLKT-LSAKQEMLQTLRQHLILHVARENSYSKVMMGESCSRLAVKLLSNIALGRGA--ALASDTGFSDPRFG---DVVIVRPMRDYSSKEITFYNRMFHVPSVFIP--GLDTKS-----------------HDKASIQRLTESFVTNLQADFPSTVSTIYRTSEKLHTVRPPQSQSTEPEPASKCLLCLCALDT-TADKASAFHATLISEQLSQLRLQEGSVDLVAGSSDQCCVEDQTCGTSGCCSSKRTPVQQDLKTLLCYSCRLTVKDMAAVNTLPPYILTEAEKRQRRSQMKVEISEYLLEEDQD---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIV3-1", "uniprot_id": "CTU2_DROME", "id": "Q9VIV3-1", "name": "Cytoplasmic tRNA 2-thiolation protein 2", "aln": "MCSIGEDDFGDEGAAHAMVVESLPLGIVLSPGNCSKCDVNSGELYKLN--FRTAECRECFLAYARHKFRAALGAAKILPRNAEVLLVLDGSAESLVLLDMLHFAQTQNTFKRLHCNARVVYVEEQQVQGR---DPVDLEALQRLSTQYAP--FDFYVIELG---ALPSSLQRIKDYSP------FLNANN--------------------------------------------------ELIHKLQKLRS-LTARQDYLQQQRKNLICSVAQCLQCTHVFESNISVDLATQLLTAIALGRGG--SAALDVALLDDRLSG--DVKLLRPLKDLTEQEIQFYIHAQRLKPHFQKGSRYGMEH-----------------GETASLQNLTSAFVANLQQNFASTVSTVFRTGDKIAVNSNPEQ--------SSCVHCRSTLDSELSDTLLAIEYS-----------------------RSVSEAGVSLYKSGQDLEGLAKKRLENKDGLCHACRAIQTELDSGNLL----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53923-1", "uniprot_id": "CTU2_YEAST", "id": "P53923-1", "name": "Cytoplasmic tRNA 2-thiolation protein 2", "aln": "----MECQRCPASARNPATVESR------KEKFCDECFIKFVSTKQRKQMMKDEYFRNLFKVIYPFEKEGSVS--KILLP---LSHSDSGSLVMLDIVHDLLLEQTKQHNNRTGFTVDVLTVFTEENVSVIKERMESLINEKMSQLNKISNIFNVHFIDVNEFFNNASEVSTFIIDNENFEIFSKSKSVDD---------------------------------------------SNILTLKEILGKYCLNNSSRSDLISIIKTQLIKHFAYENGYNAIMWGHSMTKLSEVIISLVVKGKGSQIATFLDSESFDTLNNKPCKYKNLYPMKDLLSVEIESFLQIRNLAQFLINVEETNVKPNCLIARKSLPSLGQQKLVKNMTINEITNKYFQDIQNDYSNIISTVLRTADKLTQPKSSMAKP------SQCQICQSKIYTNPSNWLNRITVTSPYPVETTEEKYLFKQWQDSKLGQSHTHYVELLNEIKQGASNSLDVEDG-DVKLCYGCLILLNTSIKDKNLVWPKVDTMDITANATNKNKELSQILDQFEINSDGEE----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * :* . * * .: .. :. ::: : .*. :: : ::: :: :: : . * ..: : ...: . : : * . : . :::.: :. : :* .* :: .. *: ::: :. *:*. * * . . : *::* *: : : : : . : .. :::.: . :. :* :.. :**: **.:*: . . * * . : :: : **:.* . . * ", "identical_positions": 30, "similar_positions": 105, "identity": "5.21%" }, { "cls_id": "homologset.agr.SGD:S000005065", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CZW5-1", "uniprot_id": "TOM70_MOUSE", "id": "Q9CZW5-1", "name": "Mitochondrial import receptor subunit TOM70", "aln": "MAASKPIEAAMAAAAAPGSGNGVGGGGGTAGPGSGAGTLPRWHVALAIGAPLLLGAGAMYLWSRRRRRREAGGRGDASGLKRNSERKTPEGRASPALGSGHHDGSGDSLEMSSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNEQSMLLADKVLKLLGKENAKEKY---------------------KNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEEN--YDKIISECSKEID---AQGKYMAEALLLRATFYLLIGSANAAKPDLDKVISLKEANVKLRANALIKRGTMCMQQQQPMLSTQDFNMAAEIDPMNSDVYHHRGQLKILLDLVEEAVADFDACIRLRPKFALAQAQKCFALYRQAYTANNSSQVQAAMKGFEEIIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKG--------LLQLQWKQDLDKGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGLKPPTL--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q75Q39-1", "uniprot_id": "TOM70_RAT", "id": "Q75Q39-1", "name": "Mitochondrial import receptor subunit TOM70", "aln": "MAASKPVEAAMAAAAAPASGNGVGSSGGTAAPGSGAGTLPRWHVALAIGAPLLLGAGAMYLWSRRRRRREAGGRGDASGLKRNSERKTPEGRASPALGSGP-DGSGDSLEMSSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNADLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNEQSMLLADKVLKLLGKENAKEKY---------------------KNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEEN--YDKIISECSKEID---AQGKYMAEALLLRATFYLLIGSANAAKPDLDKVISLKEANVKLRANALIKRGTMCMQQQQPMLSTQDFNMAAEIDPMNSDVYHHRGQLKILLDLVEEAVADFDACIRLRPKFALAQAQKCFALYRQAYTANNSSQVQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKG--------LLQLQWKQDLDKGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGLKPPTL--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O94826-1", "uniprot_id": "TOM70_HUMAN", "id": "O94826-1", "name": "Mitochondrial import receptor subunit TOM70", "aln": "MAASKPVEAAVVAAAVPSSGSGVGG-GGTAGPGTGG--LPRWQLALAVGAPLLLGAGAIYLWSRQQRRREARGRGDASGLKRNSERKTPEGRASPAPGSGHPEGPGAHLDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNQQSMLLADKVLKLLGKEKAKEKY---------------------KNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEEN--YDKIISECSKEID---AEGKYMAEALLLRATFYLLIGNANAAKPDLDKVISLKEANVKLRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEAVADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKG--------LLQLQWKQDLDRGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGLKPPTL--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKC8-1", "uniprot_id": "Q9VKC8_DROME", "id": "Q9VKC8-1", "name": "", "aln": "----------MAMTLNIGSMK-----------------LTKWQLALILGTPLAIGLGTYAVKSWTAASKELDGEKKRPKAKIEKQAISLDGTAPDQELERNQKSAELGEKLSPLKEANNYKTEGNNCYRNGKYDEAIKFYDKAIDKCPKEHRTDMAIFYQNRAASYEMLKKWSNVKEDCTASLEFNPRYAKAYYRRARAHEATKDMNECLDDVTATCILEMFQNNQTIMFADRVLKETGRLDAEKGM---------------------RNRVPVVPSACFVNTYTRSFIADPLQTMKVPAPKSDAPP------------KGFLRAHLAFLEEK--YEEIIPACTEEIESSEAEAQYKVEALLMRGTFHLLCGSYVESQQDFDAIIANDYADPNLRAYAYIKRAALYIQLDQREKGIADFAEAERLNPENPDVYHQRAQILLLLEQIEPALAEFEKAVSIAPNHAIAFVQKCYAEYRLSLLAGDQRRLESVMHTFQNAIERFPSCVECYSLTAQVLADQQQFTQAEEYYKKAMVLAPTNPALIVHQA--------IMVLQWRGDINLAVQLLNKAIEVDPKCELAYETLGTVEVQRAQLTRAVELFEKALLYAKSQAELVHVYSLRNAAVAQINVTKKLGIDMNSVSAMAQSGLMAQGVA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07213-1", "uniprot_id": "TOM70_YEAST", "id": "P07213-1", "name": "Mitochondrial import receptor subunit TOM70", "aln": "MKSFITRNKTAILATVAATGTAIG------------------AYYYYNQLQQQQQRGKKNTINKDEKKDTKDSQKETEGAKKSTAPSNPPIYPVSSNGEPDFSNKANFTAEEKDKYALALKDKGNQFFRNKKYDDAIKYYNWALELK------EDPVFYSNLSACYVSVGDLKKVVEMSTKALELKPDYSKVLLRRASANEGLGKFADAMFDLSVLSLNGDFNDASIEPMLERNLNKQAMSKLKEKFGDIDTATATPTELSTQPAKERKDKQENLPSVTSMASFFGIFKPELTFANYDESNEADKELMNGLSNLYKRSPESYDKADESFTKAARLFEEQLDKNNEDEK----LKEKLAISLEHTGIFKFLKNDPLGAHEDIKKAIELFP-----RVNSYIYMALIMADRNDSTEYYNYFDKALKLDSNNSSVYYHRGQMNFILQNYDQAGKDFDKAKELDPENIFPYIQLACLAYR-------ENKFDDCETLFSEAKRKFPEAPEVPNFFAEILTDKNDFDKALKQYDLAIELENKLDGIYVGIAPLVGKATLLTRNPTVENFIEATNLLEKASKLDPRSEQAKIGLAQMKLQQEDIDEAITLFEESADLARTMEEKLQAITFAEAAKVQQRIRSDPVLAKKIQETLAKLREQGLM--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: . * . .. . * .. . . . .. . . * * :**: :: **::**: * *:. : . **.* :*.: : . .:* : .* ::*::* * *. *** *:* . :.: *::. .: *:: . : :: *: . . :: ::: :** : :: * : . ::* ..: :*. : : ::: : .:: . : . :* . * :* .. :: *:. * *. : * . : : :: * * ::. *..**::*.*: ::*: : * :*: . : *: :. * . ** . :.: *.: .:** . * : *: *:*:::* :* : *. .: * * . : :: . :*:.** ::* :.: * :. :::*: :: .*: :*::: *:: * : :: :** .* .: .. : ", "identical_positions": 81, "similar_positions": 188, "identity": "12.29%" }, { "cls_id": "homologset.agr.SGD:S000005067", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R118-1", "uniprot_id": "HTRA1_MOUSE", "id": "Q9R118-1", "name": "Serine protease HTRA1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQSLRTTLLSLLLLLLAAPSLALPSGT-GRSAPAATVCPEHCDPTRCAPPPTDCEGGR-VRDACGCCEVCGALEGAACG----LQEGPCGEGLQCVVPFGVPAS---------ATVRRRAQAGLCVCASSE----------------------------------PVCGSDAKTYTNLCQLRAASR------------------------------------------RSEKLRQPPVIVLQRGACGQGQED-PNSLRHKYNFIADVVEK--IAPAVVHIELYRK--------------------------------------------------------------------------------------LPFSKREVPVASGSGFIVSEDGLIVTNAH---VVTN------KNRVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRP--GEFVVAIGSP----FSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIG-----------------------------------------------INTLKVTAGISFAIPSDKIKKFLTESHDRQ----AKGKAVTKKKY---IGIRMMSLTSSKAKELKDRHRDFP---------------------------------------------------------DVLSGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVTANDVSDVIK-KENTLNMVVRRGNEDIVITVIPEEIDP------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QZK5-1", "uniprot_id": "HTRA1_RAT", "id": "Q9QZK5-1", "name": "Serine protease HTRA1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQFLRTALLSLLLLLLAAPSLALPSGI-SRSAPAATVCPEHCDPTRCAPPPTDCEGGR-VRDACGCCEVCGALEGAVCG----LQEGPCGEGLQCVVPFGVPAS---------ATVRRRAQAGLCVCASSE----------------------------------PVCGSDAKTYTNLCQLRAASR------------------------------------------RSEKLRQPPVIVLQRGACGQGQED-PNSLRHKYNFIADVVEK--IAPAVVHIELYRK--------------------------------------------------------------------------------------LPFSKREVPVASGSGFIVSEDGLIVTNAH---VVTN------KNRVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRP--GEFVVAIGSP----FSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIG-----------------------------------------------INTLKVTAGISFAIPSDKIKKFLTESHDRQ----AKGKTVTKKKY---IGIRMMSLTSSKAKELKDRHRDFP---------------------------------------------------------DVISGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVTANDVSDVIK-KENTLNMVVRRGNEDIVITVVPEEIDP------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92743-1", "uniprot_id": "HTRA1_HUMAN", "id": "Q92743-1", "name": "Serine protease HTRA1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQIPRAALLPLLLLLLAAPASAQLSRA-GRSAPLAAGCPDRCEPARCPPQPEHCEGGR-ARDACGCCEVCGAPEGAACG----LQEGPCGEGLQCVVPFGVPAS---------ATVRRRAQAGLCVCASSE----------------------------------PVCGSDANTYANLCQLRAASR------------------------------------------RSERLHRPPVIVLQRGACGQGQED-PNSLRHKYNFIADVVEK--IAPAVVHIELFRK--------------------------------------------------------------------------------------LPFSKREVPVASGSGFIVSEDGLIVTNAH---VVTN------KHRVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRP--GEFVVAIGSP----FSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIG-----------------------------------------------INTLKVTAGISFAIPSDKIKKFLTESHDRQ----AKGKAITKKKY---IGIRMMSLTSSKAKELKDRHRDFP---------------------------------------------------------DVISGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVSANDVSDVIK-RESTLNMVVRRGNEDIMITVIPEEIDP------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6GMI0-1", "uniprot_id": "HTR1A_DANRE", "id": "Q6GMI0-1", "name": "Serine protease HTRA1A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MILVTLFCICALVTSLQADARLS-----KRYVIGGCPSHCDKSMCPTMPKDCSTGQ-VMDHCNCCLVCASGEGEACGGVGKLGDPVCGESLECSVTGGVSYS---------ATVRRRGKQGVCVCKSSD----------------------------------PVCGSDGVSYRDICELKRVSN------------------------------------------RAQSLQQPPVLFIQRGACGTSLHDNPNSLRYKYNFIADVVEK--IAPAVVHIELYRK--------------------------------------------------------------------------------------MVYSKREMAVASGSGFVVSDDGLIVTNAH---VVAN------KNRVKVELKNGASYDAKIKDVDEKADIALIKIDLPNKLPVLLLGRSADLRP--GEFVVAIGSP----FSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIG-----------------------------------------------INTLKVTAGISFAIPSDKIRQFLAESYDRL----ARGRGTTKKRY---IGVRMMTLTPSLSKELKGRLRDFP---------------------------------------------------------DITSGAYVIEVISKTPAAAGGLKEHDVIISINGQRISTATDVSAIIK-KESSLRVVVRRGNEDIILTIIPMEIDP------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P83110-1", "uniprot_id": "HTRA3_HUMAN", "id": "P83110-1", "name": "Serine protease HTRA3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQARALLLAALAALALAR------EPPAAPCPARCDVSRCPSP--RCPGGY-VPDLCNCCLVCAASEGEPCGG---PLDSPCGESLECVR-------------------------GLCRCRWSH----------------------------------AVCGTDGHTYANVCALQAASR------------------------------------------RALQLSGTPVRQLQKGACPLGLHQ-LSSPRYKFNFIADVVEK--IAPAVVHIELFLR--------------------------------------------------------------------------------------HPLFGRNVPLSSGSGFIMSEAGLIITNAH---VVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATIKIHPKKKLPVLLLGHSADLRP--GEFVVAIGSP----FALQNTVTTGIVSTAQREGRELGLRDSDMDYIQTDAIINYGNSGGPLVNLDGEVIG-----------------------------------------------INTLKVTAGISFAIPSDRITRFLTEFQDKQ----IKD---WKKRF---IGIRMRTITPSLVDELKASNPDFP---------------------------------------------------------EVSSGIYVQEVAPNSPSQRGGIQDGDIIVKVNGRPLVDSSELQEAVL-TESPLLLEVRRGNDDLLFSIAPEVVM-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P83105-1", "uniprot_id": "HTRA4_HUMAN", "id": "P83105-1", "name": "Serine protease HTRA4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIRPQLRTAGLGRCLLPGLLLLLVPVLWAGAEKLHTQPSCPAVCQPTRCPALPTCALGTTPVFDLCRCCRVCPAAEREVCGG---AQGQPCAPGLQCLQP------------------LRPGFPSTCGCPTLGG---------------------------------AVCGSDRRTYPSMCALRAENR------------------------------------------AARRLGKVPAVPVQWGNCGDTGTRSAGPLRRNYNFIAAVVEK--VAPSVVHVQLWGR--------------------------------------------------------------------------------------LLHGSRLVPVYSGSGFIVSEDGLIITNAH---VVRN------QQWIEVVLQNGARYEAVVKDIDLKLDLAVIKIESNAELPVLMLGRSSDLRA--GEFVVALGSP----FSLQNTATAGIVSTKQRGGKELGMKDSDMDYVQIDATINYGNSGGPLVNLDGDVIG-----------------------------------------------VNSLRVTDGISFAIPSDRVRQFLAEYHEHQ----MKGKAFSNKKY---LGLQMLSLTVPLSEELKMHYPDFP---------------------------------------------------------DVSSGVYVCKVVEGTAAQSSGLRDHDVIVNINGKPITTTTDVVKALD-SDS-LSMAVLRGKDNLLLTVIPETIN-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O43464-1", "uniprot_id": "HTRA2_HUMAN", "id": "O43464-1", "name": "Serine protease HTRA2, mitochondrial", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAPRAGRGAGWSLRAWRALGGIRWG---RRPRLTPDLRALLTSGTSDPRARVTYGT---PSLWARLSVGVTEPRACLT---SGTPGPRAQLTAVTP------------------------DTRTREASE-----------------------------------NSGTRSRAWLAVALGAGGAV------------------------------------------LLLLWGGGRGPPAVLAAVP---SPPPASPRSQYNFIADVVEK--TAPAVVYIEILDR--------------------------------------------------------------------------------------HPFLGREVPISNGSGFVVAADGLIVTNAH---VVAD------RRRVRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPLPTLPLGRSADVRQ--GEFVVAMGSP----FALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAAIDFGNSGGPLVNLDGEVIG-----------------------------------------------VNTMKVTAGISFAIPSDRLREFLHRGEKKNS---SSGISGSQRRY---IGVMMLTLSPSILAELQLREPSFP---------------------------------------------------------DVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEQMVQNAEDVYEAVR-TQSQLAVQIRRGRETLTLYVTPEVTE-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFJ3-1", "uniprot_id": "HTRA2_DROME", "id": "Q9VFJ3-1", "name": "Serine protease HTRA2, mitochondrial", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALRG-----------SHRLEVIFKRCIAS--PVLHSHAANRR------SSQLAIKEGDPNSNGN-------------------------------------------SGQYQQNG-------------------------------------EQKEKGWRRLVRFFVPFS------------------------------------------LGAVVS--AAIIQREDLTPTIAASKMTGRRRDFNFIADVVAG--CADSVVYIEIKDTRH-----------------------------------------------------------------------------------FDYFSGQPITASNGSGFIIEQNGLILTNAH---VVIN----KPHTMVQVRLSDGRTFPATIEDVDQTSDLATLRIQVNN-LSVMRLGKSSTLRS--GEWVVALGSP----LALSNTVTAGVISSTQRASQELGLRNRDINYLQTDAAITFGNSGGPLVNLDGEAIG-----------------------------------------------VNSMKVTAGISFAIPIDYVKVFLERAAEKRKKGSAYKTGYPVKRY---MGITMLTLTPDILFELKSRSQNMPS--------------------------------------------------------NLTHGVLVWKVIVGSPAHSGGLQPGDIVTHINKKEIKNSSDVYDALADNSKTLDIVILRGVKQMHVTITPEDP--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53920-1", "uniprot_id": "NM111_YEAST", "id": "P53920-1", "name": "Pro-apoptotic serine protease NMA111", "aln": "MTISLSNIKKRDHSKISDGTSGESSLVKRKQLESATGDQEEEYTDHEIIIEPLHFANNNNTVLTDSENYLRWQNTISNVVKSVVSIHFSQVAPFDCDSALVSEATGFVVDAKLGIILTNRHVVGPGPFVGYVVFDNHEECDVIPIYRDPVHDFGFLKFDPKNIKYSKIKALTLKPSLAKVGSEIRVVGNDAGEKLSILAGFISRIDRNAPEYGELTYNDFNTEYIQAAASASGGSSGSPVVNIDGYAVALQAGGSTEASTDFFLPLDRILRALICIQTNKPITRGTIQVQWLLKPYDECRRLGLTSERESEARAKFPENIGLLVAETVLREGPGYDKIKEGDTLISINGETISSFMQVDKIQDENVGKEIQLVIQRGGVECTVTCTVGDLHAITPHRYVEVCGATFHELSYQMARFYALPVRGVFLSSASGSFNFDSKERVGWIVDSIDNKETPDLDTFIEIMKTIPDRKRVTVRYHHLTDQHSPLVTSIYIDRHWCNEFRVYTRNDTTGIWDYKNVADPLPADALKPRSAKIIPIPVNNEKVAKLSSSLCTVATMAAVPLDSLSADILKTSGLIIDAEKGYVLVSRRVVPHDCLDTFVTIADSLVVPATVEFLHPTHNFAIVKYDPELVKAPLITPKLSTTRMKRGDKLQFIGFTQNDRIVTSETTVTDISSVSIPSNLIPRYRATNLEAISIDCNVSTRCNSGILTDNDGTVRGLWLPFLGERLENKEKVYLMGLDIMDCREVIDILKNGGKPRVSIVDAGFGSISVLQARIRGVPEEWIMRMEHESNNRLQFITVSRVSYTEDKIHLETGDVILSVNGKLVTEMNDLNGVVSSADGILPSAMLDFKVVRDGNIVDLKIKTVEVQETDRFVIFAGSILQKPHHAVLQAMVDVPKGVYCTFRGESSPALQYGISATNFITHVNEIETPDLDTFLKVVKTIPDNSYCKMRLMTFDNVPFAISLKTNYHYFPTAELKRDNITHKWIEKEFTGNSQSEK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : .:*. : . ..::: :. . *. :: ***: : :* * : .. * : :. ::* :: . . : : : * *: : :* . : .:* .:.: * ::: :. *. : ..* *.: ** . * ..:: * . .:* : : : . .: : * : ::. *:: .. :: * :.: *: :.: :. . : . : . ", "identical_positions": 26, "similar_positions": 99, "identity": "2.61%" }, { "cls_id": "homologset.agr.SGD:S000005068", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q52KK4-1", "uniprot_id": "NAF1_RAT", "id": "Q52KK4-1", "name": "H/ACA ribonucleoprotein complex non-core subunit NAF1", "aln": "---------------------------------------------------------------------------------MEVVEAAA-QLQTLKFGGSGPGSAASPPPEER-----PDAEQAEQAPPAGEQPPP--APSSDA--GENPPPPSGP-----------------------CATAPDAAEPL--PELQDSDSSDSDSDSETDSDSSSSSSSSSSSSSS-------CGSLPPVLSDGEEDVQVEKENK-NFPLKTKDELLLNELPSVEELTVTLPEDIALKPLGKVSSIIEQ-LVIIESMTNIPPVNEDTVIFK-SDRQAAGKIFEIFGPVAHPFYVLRFNSSEHIESKGIKIKDTMYFAPSMKDFTQYIFTEKLKQDRGSDASWKNDQEPPPEALDFSDDEKEKEAKQRKKSQIQGRKKLKSELNESGEDFGEVHQNWNAN------------SSS-EHSKG-YHNREFTRGFPRGRYSRGSHGRPPPQQY-----YNSDPMASQESLGFPPQRQDNPVMPHYP--------FPPPMFDMHNFPLPPPPPPPP--TVSMGWAAPSMTS------HPVLNLPYSLPPP-----PLPPPPPPP--SPGESNSSHFGSYY-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UMQ8-1", "uniprot_id": "NAF1_MOUSE", "id": "Q3UMQ8-1", "name": "H/ACA ribonucleoprotein complex non-core subunit NAF1", "aln": "---------------------------------------------------------------------------------MEVVEAAA-QLQTLKFGGSGQGSAAPQPPEDRREAPPPGVQPPPPAPSGRPPPPP--APSSDP--GGRPPPPPAPNWDAGGRPPPPPAPNSDPPPGGAWVTGRNAAEPP--PVLQASDSSDSDSDSETDSDSSSSSSSSSSSSSS-------CVSFPPVLSDGDEDFQLEKENK-NFPLKTKDELLLNELPSVEELTVILPEDIALKPLGKVSSIIEQ-LVIIESVTNIPPVNEDTVIFK-SDRQAAGKIFEIFGPVAHPFYVLRFNSSDHIESKGIKINDTMYFAPSMKDFTQYIFTEKLKQDRGSDASWKNDQEPPPEVLDFSDDEKEKEAKQRKKSQIQGRKKLKSELNESGEDFGEVHENWNAY------------SSS-EHSKG-YHHREFSRGFARGRYSRRSHGRPPPQQY-----YNSDHMASQESLGFTPQRQDNPVMPHYP--------FPPPMFDMHNFPLPPPPPPPPPPPPSMGWAAPSMAS------HPVLNLPYSMPPP-----PLPPPPPPPPPSPGENNSSHFGPYF-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96HR8-1", "uniprot_id": "NAF1_HUMAN", "id": "Q96HR8-1", "name": "H/ACA ribonucleoprotein complex non-core subunit NAF1", "aln": "---------------------------------------------------------------------------------MEVVEAAAAQLETLKFNGTDFGVGEGPAAPSPGSAPVPGTQPPLQSFEGSPDAGQ--TVEVKP--AGEQPLQPVLNAVAAGTPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSS---CISLPPVLSDGDDDLQIEKENK-NFPLKTKDELLLNELPSVEELTIILPEDIELKPLGMVSSIIEQ-LVIIESMTNLPPVNEETVIFK-SDRQAAGKIFEIFGPVAHPFYVLRFNSSDHIESKGIKIKETMYFAPSMKDFTQYIFTEKLKQDKGSDASWKNDQEPPPEALDFSDDEKEKEAKQRKKSQIQGRKKLKSEFNEPGEDFTEVHQNWNAH------------SSASEHAKG-YRNREFTRGFSRARYPRSCHGRPPPQHF-----YNSEHMVSQETSGFPSQRQNNPIMPQYP--------FPLPVFDMHNFPLRPPPPPPPP-PVNMGWATPNMAA------HPLLNLPYSLPPP-----PPPPPLPPPP-SSGDSNS-HFGPYY-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QXL6-1", "uniprot_id": "F1QXL6_DANRE", "id": "F1QXL6-1", "name": "H/ACA ribonucleoprotein complex non-core subunit NAF1", "aln": "-----------------------------MLFTHGELNMENSSTENATYSQDQDETKSKKDEMELDIKTENTDVLIGPTDEPCTSEQRDDQISSIQPEQSSKENSEHQLVKEEDFTSDHAGLTGEDQSSGGQPALIRDALTSDQ--SGRADQSSNIKSEPIDEQICSVQSGPAEMQYGTVVSPQSGTGSLALLSMQYRGNSSDDNCSDSDSDSSSSTSSSSSSSSSSSSEPFEVVIMPNKAEDDDDDEGFAGGNKKSAPVKTQDELLIDDLPAVENLIISLPEDTEMEPIGTISSIVDQ-LVIVESYKNLPPLNEESVLFS-KNRNSVGKVFEIFGPVCQPFYVLRFNSHDDIEQKDLKVRDPVYFAPKLKDFTDYIFTDKLKTLKGSDASWKNDQEPPPEALDFSDDEQERLAKQKLKEQKRRQQNDSDSEDESDAQKMPQKAARRKP------------RQNRNHPRGQYHNR-------GGGFHSNFHAHPR---------FPPEYMLPHPDPQMFPYQG--PMVPHFP--------RPSP-YHMGMAPWPPGP-----------------------------NQGFMFQPP-----PPPPPPPYQ---------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJ62-1", "uniprot_id": "NAF1_DROME", "id": "Q9VJ62-1", "name": "H/ACA ribonucleoprotein complex non-core subunit NAF1", "aln": "MESEQPAAVKASAPIEEPQSTETAVELGKHSTLKADLSIDKLETATTEATNAVVEPVEMEQQVENELVNESTQAMTSTTTQEKVVGSVNNLVEEQQCVEMEFETSSDLVVQGSPSEESKKVASDASATVTAPQVQPAPHVDSSPQASGLSLLAAYSSDDSDDEKVTPVQNGDNDVIEVPVTDPASSTTAYRPVVAVSSDDESSKSSSSSSDSDSDSEGEYLTVLRKKIDKRINTVDCDEDDEDFDEDGATGDRSRRRQPPKVRGEMLLDDLPPIHQLEITVPED-ECVELGKVQSIVDQ-LVLVSVLPNSMLFDLDTVLFLEKGRKVLGEVFDVLGQVSDPLYCVRFNSNKQILDRGIKIGDVVYCAP-KTEHTQFVILSKLMQVRGSDASWEHDVEPPARYVDHSDDEEEREARAEQRKRRQRDRTNSTDSVDTVTSVATTATKASSV------------APP-PRQRGRRGQRESFRQSQRPSINQHNQNQPQDEQYNFHPSYNPGSWHSNYYQNYHQAAANFNMAQQHPG-----MPFPVPNYGYGMPYAMPP------------------------------MYPHMYPPP-----PPFAPPPPNNQSHQGQPPPS----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53919-1", "uniprot_id": "NAF1_YEAST", "id": "P53919-1", "name": "H/ACA ribonucleoprotein complex non-core subunit NAF1", "aln": "---------------------------------------------------------------------------------------MSDDLFSKALENPDQDLNVELPKDDVDLGLLGDGGNERKTDEPVADAERSTGLGSGS------------------------------------------------------SESESDSGSDSDSDSGSSGSEDDSADQD--------VEGEDEGGDAIENEDEDEDPSPSGPILSKNEILEETVPELP-EDYEISEKTIITPIGVLKSAFENNIIIHATMSGEKRVLKEGSIFCLEDRTLIGMLTEVFGPLQNPFYRIKLPDSKKNLFDELKVR-LGEKAFIVTPDAHWIDTFELKRNKGTDASNGYDEELPEEEQEFSDDEKEALFKKMKKQQRQRKKRDNRKLANDSDNVKVKRARQPKANSLPKLVPPLGMSSNAPMQHG-YKSRNARENIKRESSATSNRNGSSPVPIT----QHHQQQFSANNYPFPQQPNGMPYPPYSPFPQPTNFQYPPPPFGQATPAQFSNTVPYGSLPPAYNNMSPPTQQSFMPMTQSQPPLPYGVPPMNQMQNPMYIQPPPQAPPQGNGNFQQVMELHQILLQQQQQQHQYQHQHQQDPRT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ....... *.:......* .. : . * :: * :.*:* : :* : :.*. :* :.* .:: ::: . . : :* ..* * : :::* : .*:* ::: . .. :*: * . :.:: :* :*:*** * * * . :.****:* : :.: : : . . : . :* * : . . * * * : . . * * * ", "identical_positions": 39, "similar_positions": 90, "identity": "6.02%" }, { "cls_id": "homologset.agr.SGD:S000005069", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70324-1", "uniprot_id": "MOT8_MOUSE", "id": "O70324-1", "name": "Monocarboxylate transporter 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALPSPASEEAEGPCQEANQEYQEPVCSPVPEPEPEPEPEPEPDPEPVPVPPPEPQPEPEPQPLPDPAPLPELGFEAEPVQEPEPTPTVETRGTARGFQPPEGGFGWIVVFAATWCNGSIFGIHNSVGILYSMLLEE-EKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATTGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCG---CSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIKMLGDKIKLAQTFQVLSTFMFVLTLLSLTYRPLLPS----------------------------------------------------------------------------------------------------------------------------------------------------------------------SQDTPSKRGAH------------------------------------TLRQRFLVQFRKYFNMRVFRQ------RTYRIWAFGIAAAALGYFVPYVHLMKYVEDKFK---EIKETWVLLVCIGATSGLGRLVSGHISDSIP-----GLKKIY----LQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFE--LVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVA---FYFAGVPPIIGAVILFFVPLMHQRMFK---KEQR----------------------------------------------------------------DSSKDKMLSHDPDPNGELLPGSPTPEEPI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K1P8-1", "uniprot_id": "MOT8_RAT", "id": "Q8K1P8-1", "name": "Monocarboxylate transporter 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALPSPASEEAEGPCQEANQEYQEPVCSPVPEPEPEPEPEPEPEPEPVPVPPPEPQPEPEPQPLPDPAPLPVLGFEAEPVQEPEPTPTVETRGTARGFQPPEGGFGWIVVFAATWCNGSIFGIHNSVGILYSMLLEE-EKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATTGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCG---CSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIKMLGDRIKLAQTFQVLSTFMFVLTLLSLTYRPLLPS----------------------------------------------------------------------------------------------------------------------------------------------------------------------SQDTPSKRGAH------------------------------------TLRQRFLVQFRKYFNMRVFRQ------RTYRIWAFGIAAAALGYFVPYVHLMKYVEDKFK---EIKETWVLLVCIGATSGLGRLVSGHISDSIP-----GLKKIY----LQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFE--LVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGNYHVA---FYFAGVPPIIGAVILFFVPLMHQRMFK---KEQR----------------------------------------------------------------ESSKDKMLSHDPDPNGELLPGSPTPEEPI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36021-1", "uniprot_id": "MOT8_HUMAN", "id": "P36021-1", "name": "Monocarboxylate transporter 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALQSQASEEAKGPWQEADQEQQEPVGS----PEPESEPEPEPEPEPVPVPPPEPQPEP--QPLPDPAPLPELEFESERVHEPEPTPTVETRGTARGFQPPEGGFGWVVVFAATWCNGSIFGIHNSVGILYSMLLEE-EKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCG---CSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIRMLGDKIKLAQTFQVLSTFMFVLMLLSLTYRPLLPS----------------------------------------------------------------------------------------------------------------------------------------------------------------------SQDTPSKRGVR------------------------------------TLHQRFLAQLRKYFNMRVFRQ------RTYRIWAFGIAAAALGYFVPYVHLMKYVEEEFS---EIKETWVLLVCIGATSGLGRLVSGHISDSIP-----GLKKIY----LQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFE--LVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVA---FYFAGVPPIIGAVILFFVPLMHQRMFK---KEQR----------------------------------------------------------------DSSKDKMLAPDPDPNGELLPGSPNPEEPI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G8XYX6-1", "uniprot_id": "MOT8_DANRE", "id": "G8XYX6-1", "name": "Monocarboxylate transporter 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHSESDDNTAGGTPGSEDPQ------------AEESSSPAEEFEEQERKLAPEDS-----------TVQLIHTGCTD---KRPATPPGAHP---GQGFVPPEGGFGWVVVFAATWCNGSIFGIQNSFGILHMMLVKHHEKQPDQASQFKVAWVGALAMGMIFFCSPVVSMFTDHFGCRKTAVCGAFVAFIGLLTSSFATTLGLWYFTYGILFGCG---SSFAFQPSLVILGHYFRQRLGLANGVVTAGSSLFSMGLPVLLKKVVEPLGLPRTFQILSIFMLVQALLALAFKPLLPSGMCPMPGM-------------------------------------------------------------------------------------------------------------------------------------------------------------ALDGGPSTPESA------------------------------------SRWQKGLAKIRRYFNVRVFSI------LTYRIWAFGVATAVLGYFVPYVHLLNFVKEQFG---DTQREWLLLVCIGASSGVGRLLFGKIGDLIP-----GVKKIY----MQVASFILLGVMSMMIPQCAVFEGLVVVFVLMGLCDGCFITIMAPIAFE--LVGPMQASQAIGYLLGLMAIPMTAGPPIAGLLHDHFGNYHVA---FYLAGVPPIVGGIVMFFVPLVHQRMQKR-RKETD----------------------------------------------------------------DPSMDKMLKN--CSNGDMLPGYTDMETHI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3U9N9-1", "uniprot_id": "MOT10_MOUSE", "id": "Q3U9N9-1", "name": "Monocarboxylate transporter 10", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVPSQEEP-AAERETNEAQPPGP---------APSDDAPLPGPGPSDVSDVAAEK---------------VEVELT--RSAGS------------EPPVPPEGGWGWLVMLAAMWCNGSVFGIQNAYGVLFVSMLDTFKAKDDDNMAFKTAWVGSLSMGMIFFCCPIVSVFTDMFGCRRTAVVGAAVGFIGLMSSSFVSSIEPLYLTYGIIFACG---CSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLGNLISSVKLFNTLRILCIFMFVLFLAGFTYRPLVPS---------------------------------------------------------------------------------------------------------------------------------------------------------------------TKEKESGGSRSS------------------------------------FFSRRKLSPPKKVFNFALFKE------TTYAVWAAGIPLALFGYFVPYVHLMNHVKERFQ---DVNNKEVLFMCIGITSGVGRLLFGRIADYLP-----GVKKVY----LQVLSFFFIGLMSMMIPLCSAFGALIAVCLAMGLFDGCFISIMAPIAFE--LVGPQDASQAIGFLLGFMSIPMTVGPPIAGLLHDKLGTYDVA---FYLAGIPPFVGGVVLCLIPWIHSKKQRKISKNAG----------------------------------------------------------------GEKMEKMLENQSSLLSGSSGIFKKDSASII---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91Y77-1", "uniprot_id": "MOT10_RAT", "id": "Q91Y77-1", "name": "Monocarboxylate transporter 10", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVPSQEEPAAAERETNEAQPPGP---------APSDDAPLPVPGPSDVSDGSVEK---------------VEVELT--RSTGNQ-----------EPPEPPEGGWGWLVMLAAMWCNGSVFGIQNAYGVLFVSMLETFGAKDDDNMAFKAAWVGSLSMGMIFFCCPIVSVFTDMFGCRRTAVLGAAVGFVGLMSSSFVSSIEPLYFTYGVVFACG---CSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLGNLTSTVGLCYTLRILCIFMFVLFLAGFTYRPLVPS---------------------------------------------------------------------------------------------------------------------------------------------------------------------SKEKESEDSRSS------------------------------------FFSRRKLSPPKKIFNFALFKE------TAYAVWAAGIPLALFGYFVPYVHLMNHVKERFK---DVNNKEVLFMCIGVTSGVGRLLFGRIADYLP-----GVKKVY----LQVLSFFFIGLTSMMIPLCSVFGALIALCLIMGLFDGCFISIMAPIAFE--LVGPQDASQAIGFLLGFMSIPMTVGPPVAGLLHDKLGSYDLA---FYLAGIPPFIGGAVLCLIPWIHSKKQREISKNTG----------------------------------------------------------------GEKMEKMLANQSSLLSSSSGIFKKESDSII---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TF71-1", "uniprot_id": "MOT10_HUMAN", "id": "Q8TF71-1", "name": "Monocarboxylate transporter 10", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLSQEEP-DSARGTSEAQPLGP---------APTGAAPPPGPGPSDSPEAAVEK---------------VEVELAGPATAEPH-----------EPPEPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACG---CSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCIFMFVLFLAGFTYRPLATS---------------------------------------------------------------------------------------------------------------------------------------------------------------------TKDKESGGSGSS------------------------------------LFSRKKFSPPKKIFNFAIFKV------TAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQ---DEKNKEVVLMCIGVTSGVGRLLFGRIADYVP-----GVKKVY----LQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPIAFE--LVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVA---FYLAGVPPLIGGAVLCFIPWIHSKKQREISKTTG----------------------------------------------------------------KEKMEKMLENQNSLLSSSSGMFKKESDSII---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L1W9-1", "uniprot_id": "MOT10_DANRE", "id": "A1L1W9-1", "name": "Monocarboxylate transporter 10", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTEPEPTLEQEPTPEPEPTQE---------PTPEPTPEPEPTQEPESEPELELK--------------QENGCTKASEQKSP-----------EEFEPPEGGWGWVVMLASMWCNGSVFGIQNAFGIMFVYLLNEFGSEHDADLRFKTAWVGSLSMGMIFFCSPIVSVFTDLLGCRITAVGGAAVGCVGLLASSFVTSLGPMYFTYGIVFACG---CSFAYQPSLVILGHYFKRRLGLVNGIVTAGSSVFTITLPYMLSGLLKSVGLYHTLRVLAIFMFILMLAGLTYKPLLPK---------------------------------------------------------------------------------------------------------------------------------------------------------------------PVSSSKPGSRCP------------------------------------PLSR--------IFNVNIWKS------LGYRIWAFGIPAALYGYFVPYVHLMTHVEERFG---PEANKEVLLACIGITSGVGRLIFGRVADYVP-----GVNKVF----LQVSSFMVIGVMSMMIPLCHVFGGLIAVCLLMGLFDGCFICIMAPIAFE--LVGSQNVSQAIGFLLGMMSIPMTVGPPIAGFLRDRLGSYDVA---FYLAGIPPLIGGAVLCAIPWVEARRKRREAANT-----------------------------------------------------------------AENTEKMLESRSPPLEDTVCRTE-EPESVI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B1AT66-1", "uniprot_id": "MOT7_MOUSE", "id": "B1AT66-1", "name": "Monocarboxylate transporter 7", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRASGQGPQRRRRGWATRDDSAVTFRDPQPRQPAGGARALRGPDPRGPARAHQAGPLLAGARRSQHMVGGAPPRPAETGCSRSRMTQKNSKLCARANVYTQVPDGGWGWAVAVSFFFVEVFTYGIIKSFGVFFNDLMDSFDESNS-----KISWIISICVFVLTFTAPLSTVLSNRFGHRLVVMAGGLLISLGMITASFSQRVYHMYISIGVISGLG---YCFSFLPTVTILSQYFDKRRSVVTAVASTGECFAVFAFAPAITALKEHIGWRYSLLFVGLLQLNIMVCGALLRPIIIQGPGQSPKAVTL------------------------------------------------------------------------------------------------------------------EPRRE-----------------VQYMLENEKTRTSIDSIDSGVELTTSPKNVPSE-----------------AKMEQETRAEQQQTLVTA-PKHSQMKAPLLDFSVLKE------KSFICYALFGLFATLGFFAPSLYIIPLGISLGI---DPDRAAFLLSTMAIAEVFGRIGAG-FVLNR-----EPIRKIY----IELICVILLTASLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPMLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRA---FYSCAAGMCLAAVCLALVRPCKKGLCQNSHS--------------GENQTDRQRGKALQDIPEDFL----------------------------------EMDLGKCEHRAHMKMDPV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TMR7-1", "uniprot_id": "MOT7_RAT", "id": "Q7TMR7-1", "name": "Monocarboxylate transporter 7", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNS-----KISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLG---YCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPG-SPKAIPL------------------------------------------------------------------------------------------------------------------EPRRE-----------------VQYMLENEKTRTSIDSIDSGVELTTSPKNVPSE-----------------AKREQEVRVEQQQTLVVG-PKHSQKRAPLLDFSILKD------RSFICYTLFGLFATLGFFAPSLYIIPLGISLGI---HPDRAAFLLSTMAIAEVFGRIGMG-LVLNR-----EPIRKIY----IELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRA---FYSCAAGMALAAVCLALVRPCKKGLCQNPHS--------------GENQTDGHRGKALQDIPEDFL----------------------------------EMDLGKCEPRAHMKMDPV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15403-1", "uniprot_id": "MOT7_HUMAN", "id": "O15403-1", "name": "Monocarboxylate transporter 7", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQNKLKLCSKANVYTEVPDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNS-----RISWIISICVFVLTFSAPLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLG---YCFSFLPTVTILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGALLRPIFIRGPA-SPKIVIQ------------------------------------------------------------------------------------------------------------------ENRKE-----------------AQYMLENEKTRTSIDSIDSGVELTTSPKNVPTH-----------------TNLELEPKADMQQVLVKTSPRPSEKKAPLLDFSILKE------KSFICYALFGLFATLGFFAPSLYIIPLGISLGI---DQDRAAFLLSTMAIAEVFGRIGAG-FVLNR-----EPIRKIY----IELICVILLTVSLFAFTFATEFWGLMSCSIFFGFMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQSIAGLAGPPLAGLLVDQSKIYSRA---FYSCAAGMALAAVCLALVRPCKMGLCQHHHS--------------GETKVVSHRGKTLQDIPEDFL----------------------------------EMDLAKNEHRVHVQMEPV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PFG6-1", "uniprot_id": "A0A8M9PFG6_DANRE", "id": "A0A8M9PFG6-1", "name": "Monocarboxylate transporter 13", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERKR----GTAGPAGPPLDGGYGWFIVLSTFLVFGLTFGVIKSFGVFFVEIHHYFSTTAT-----ASSWITSISVATVHIGAPVGSALSTYFGHRPVVMAGGLLSSVGMVLGSFAQDLLQLYITVGFLTGFG---YALTWTPTVTMLGWYFDKRRPVANALSSTGECLLTFILTPSFQLMVDQFSWRGAMLILGALQLNLCVCGALLRPLSR----------------------------------------------------------------------------------------------------------------------------------------------------------HDYFKDSIE--ENEHELSKCSNNRADS-----------------DPMKVKVIR-------------------YVDYTLIAN------SRFMVYSMFGIFAALGFFAPSLFLVPYARSQGV---EEYQAASLMSISAVLDLLGRVFFG-WVANL-----RLVETVH----QLIGTVVLLGAVLLLCPLATTFTQLAVFSAGYGLVFGATVAIHITVLAE--VVGVERLGSALGFFMLIRSSGGLLGPPLAGIFIDKMSDYGAG---FLMAGVALLVSALFLIVLHFMNK----------------------KETEHKKDICSENEEEHEDLK----------------------------------NRNFVFGKS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O70451-1", "uniprot_id": "MOT2_MOUSE", "id": "O70451-1", "name": "Monocarboxylate transporter 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSEP-----SAPLPQPLPPDGGWGWVVVCASFISIGFSYAFPKAVTVFFKDIQEIFNTTSS-----QIAWISSIMLAVMYAGGPISSVLVNNYGSRPVVIVGGLLCCIGMILASYSNSVIELYLTVGFIGGLG---LAFNLQPALTIIGKYFYRRRPLANGCAMAGSPVFLSTLAPFNQYLFNNYGWKGSFLILGGIFLHSCVAGCLMRPVGPSPNTK-----------------------------------------------------------------------------------------------------------------------------------------------------------------KSKSKVGSRHD--------------------------------STLKKASKVSTAQKVNRFLDFSLFMH------RGFLIYLSGNVILFLGIFAPIIFLAQYAKHIGV---DDYNSAFLLSVMAFIDMFARPSVG-LIANT-----SLIRPRI--QYLFSSAIIFTGICHLLCPLATTYSALVVYVVFFGLGFGSISSLLFECLMD--IVGATRFSSAVGLTTIVECCPVLFGPPLAGKLLDITGEYKYL---YIASGTVVLVSGTYLLIGNAINYRLLDKERK--------------REKAKKKKSASHASREMEALNRSKQ-----------------------------DEVTVKASNAHNPPSDRDK------------ESNI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63344-1", "uniprot_id": "MOT2_RAT", "id": "Q63344-1", "name": "Monocarboxylate transporter 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSESSVKATAAPPPFPLPPDGGWGWVVVCASFISIGFSYAFPKAVTVFFNDIKDIFKTTSS-----QIAWISSIMLAVMYAGGPISSVLVNNYGSRPVVIVGGLLCCTGMILASFSSSVIELYLTVGFIGGLG---LAFNLQPALTIIGKYFYRKRPLANGFAMAGSPVFLSTLAPFNQFLFNSYGWKGSFLILGAIFLHSCVAGCLMRPVGPSPRAA-----------------------------------------------------------------------------------------------------------------------------------------------------------------KSKSKVGSRQD--------------------------------SSTKRLSKVSTAEKINRFLDFGLFTH------RGFLIYLSGNVVLFLGMFAPIIFLAPYAKDKGV---DDYNSAFLLSVMAFTDMFARPSVG-LIANT-----SLIRPRI--QYLFSVAIMFTGICHLLCPLAHSYTALVVYVIFFGIGFGSISSLLFECLMD--QVGASRFSSAVGLVTIVECCPVLFGPPLAGKLLDITGQYKYL---YIASGIVVLSSGIYLLICNAINYRLLEKERK--------------REKARRKKSASQASKEMEALSRSKQ-----------------------------DDVTVKVSNTHNPPSDRDK------------ESSI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60669-1", "uniprot_id": "MOT2_HUMAN", "id": "O60669-1", "name": "Monocarboxylate transporter 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPMP-----SAPPVHP-PPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYS-----EIAWISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLG---LAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGSLMRPLGPNQTTS-----------------------------------------------------------------------------------------------------------------------------------------------------------------KSKNKTGKTEDD------------------------------SSPKKIKTKKSTWEKVNKYLDFSLFKH------RGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGI---DEYSAAFLLSVMAFVDMFARPSVG-LIANS-----KYIRPRI--QYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMD--LVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYM---YMSCGAIVVAASVWLLIGNAINYRLLAKERK--------------EENARQK------TRESEPLSKSKHS----------------------------EDVNVKVSNAQSVTSER--------------ETNI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N837-1", "uniprot_id": "A0A8M1N837_DANRE", "id": "A0A8M1N837-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPSA-----STNLGYT-PPDGGWGWAVVFGSFISIGFSYAFPKSLTIYFKEIQEYFSISYS-----QIAWVSSIMLATMYAGGPVSSILVNRYGSRPVVIAGGLMVGVAMVTASFGTSILHLYLCVGVIGGFG---LAFNLQPALTIIGKYFLVKRPMANGIAMAGSPVFLSTLAPVNQFLFDQFGWRGSFFILGGVLFNCCVAGSLMRPIKIPVSKT-----------------------------------------------------------------------------------------------------------------------------------------------------------------TEDNISPQTAG----------------------------------QDESKPSGCSSKLNQFIDISLFKH------RGFLIYLVGNVLMFFGFFAPVVFLAPYAKHQGV---DEYSAAFLLSIFALVDMFARPGTG-LVANT-----KWIRPKI--QYFFSFAVTYNGLCHLMCPLLPGYIDLVVYAVLFGLAFGMVCALLFEVLMD--LVGAQRFSSAVGLATIIECGPVLLGPPISGLLVDIFMDYKYM---YFACGMMMLAGGVFLFIMNYYNYRWLKKEEK--------------QRNAEELQIFS--TKELAAI-----------------------------------DEEIKLSIEEKLKD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53986-1", "uniprot_id": "MOT1_MOUSE", "id": "P53986-1", "name": "Monocarboxylate transporter 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPAIG-----GPVGYT-PPDGGWGWAVLVGAFISIGFSYAFPKSITVFFKEIEVIFSATTS-----EVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYLCIGVIGGLG---LAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFDIFDWRGSFLILGGLLLNCCVAGSLMRPIGPEQVKLEKL--------------------------------------------------------------------------------------------------------------------------------------------------------------KSKESLQEAGKS------------------------DANTDLIGGSPKGEKLSVFQTINKFLDLSLFTH------RGFLLYLSGNVVMFFGLFTPLVFLSSYGKSKDF---SSEKSAFLLSILAFVDMVARPSMG-LAANT-----KWIRPRI--QYFFAASVVANGVCHLLAPLSTTYVGFCVYAGVFGFAFGWLSSVLFETLMD--LIGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYT---YWACGVILIIAGIYLFIGMGINYRLLAKEQK--------------AEEKQKREGKEDEASTDVDEKPKETM----------------------------KAAQSPQ--QHSSGDPTEE------------ESPV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53987-1", "uniprot_id": "MOT1_RAT", "id": "P53987-1", "name": "Monocarboxylate transporter 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPAIG-----GPVGYT-PPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTS-----EVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLG---LAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKL--------------------------------------------------------------------------------------------------------------------------------------------------------------KSKESLQEAGKS------------------------DANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTH------RGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHF---SSEKSAFLLSILAFVDMVARPSMG-LAANT-----RWIRPRV--QYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMD--LVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYT---YWACGVILIIAGLYLFIGMGINYRLVAKEQK--------------AEEK-KRDGKEDETSTDVDEKPKKTM----------------------------KETQSPAPLQNSSGDPAEE------------ESPV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53985-1", "uniprot_id": "MOT1_HUMAN", "id": "P53985-1", "name": "Monocarboxylate transporter 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPAVG-----GPVGYT-PPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTS-----EVSWISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLG---LAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGALMRPIGPKPTKAGKD--------------------------------------------------------------------------------------------------------------------------------------------------------------KSKASLEKAGKSGVK-----------------KDLHDANTDLIGRHPKQEKRSVFQTINQFLDLTLFTH------RGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHY---SSEKSAFLLSILAFVDMVARPSMG-LVANT-----KPIRPRI--QYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFAFGWLSSVLFETLMD--LVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYT---YWACGVVLIISGIYLFIGMGINYRLLAKEQK--------------ANEQ-KKESKEEETSIDVAGKPNEVT----------------------------KAAESPDQ-KDTDGGPKEE------------ESPV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F7B3-1", "uniprot_id": "E7F7B3_DANRE", "id": "E7F7B3-1", "name": "Monocarboxylate transporter 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPAVG-----GPVGYT-PPEGGWGWAVVLGAFISIGFSYAFPKSITVFFKEIEVIFNATSS-----QVSWISSIMLAVMYGGGPVSSILVNKYGSRPIMILGGCLSGAGLIAASFCNTVEGLYFCVGVVGGLG---LAFNLNPALTMIGKYFYKKRPIANGIAMAGSPVFLSTLAPLNTWFFDQFGWRGSFLILGGLLLNCCVAGSLMRPIGPKP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------QPAVKADNS--------------------------------NSRAKERKTVVEVINGFIDLTLFKH------RGFLLYLLGNVVMFFGLFSPLVFLSNYAKSKQI---PREKAAFLLSILAFVDMVARPSMG-IVANT-----KWVRPRV--QHFFAASILLNGVCHLLAPLSTDYTGFVIYAIFFGFAFGWLSSVLFETLMD--LVGAQRFSSAVGLVTIVECGPVLLGPPLLGKFNDIYHDYKYT---YMGCGIVLLIGSLFLFVGMGINYKLLEREAK--------------EESK--KANQQDDPGKEVVEALK------------------------------------------AAEDNAAE------------EAV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O35308-1", "uniprot_id": "MOT3_MOUSE", "id": "O35308-1", "name": "Monocarboxylate transporter 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MG-------AGGPRRGAGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRELKRDFGAGYS-----DTAWVSSIMLAMLYGTGPLSSILVTRFGCRPVMLAGGLLASAGMILASFASRLVELYLTAGVLTGLG---LALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSMLSPLGQLLGERFGWRGGFLLFGGLLLHCCACGAVMRPPPGPPPRRD------------------------------------------------------------------------------------------------------------------------------------------------------------------PSPHGGPAR----------------------------------------------RRRLLDVAVCTD------RAFVVYVVTKFLMALGLFVPAILLVNYAKDAGV---PDAEAAFLLSIVGFVDIVARPACG-ALAGL-----GRLRPHV--PYLFSLALLANGLTDLISARARSYGTLVAFCIAFGLSYGMVGALQFEVLMA--TVGAPRFPSALGLVLLVEAVAVLIGPPSAGRLVDALKNYEII---FYLAGSEVALAGVFMAVTTYCCLRCSKNISS--------------GRSAEGGASDPEDVEAERDSEPMPASTE--------------------------EPGSLEALEVLSPRAGSPEQEPEEEAVPELDHESIGGHEARGQKA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70461-1", "uniprot_id": "MOT3_RAT", "id": "O70461-1", "name": "Monocarboxylate transporter 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MG-------AGGPRRGAGPPDGGWGWVVLGACFVITGFAYGFPKAVSVFFRELKRDFGAGYS-----DTAWVSSIMLAMLYGTGPLSSILVTRFGCRPVMLAGGLLASAGMILASFASRLLELYLTAGVLTGLG---LALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSTLSPLGQLLGERFGWRGGFLLFGGLLLHCCACGAVMRPPPGPQPRPD------------------------------------------------------------------------------------------------------------------------------------------------------------------PAPPGGRAR----------------------------------------------HRQLLDLAVCTD------RTFMVYMVTKFLMALGLFVPAILLVNYAKDAGV---PDAEAAFLLSIVGFVDIVARPACG-ALAGL-----GRLRPHV--PYLFSLALLANGLTDLISARARSYGTLVAFCIAFGLSYGMVGALQFEVLMA--TVGAPRFPSALGLVLLVEAVAVLIGPPSAGRLVDALKNYEII---FYLAGSEVVLAGVFMAVTTYCCQRCSKDIPP--------------GPSAEGGTSDTEDVEAERDSEPMPASTE--------------------------EPGSLEALEVLSPRAGSPE--PEEEAVPDLSHESVGGHEAHGQNA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95907-1", "uniprot_id": "MOT3_HUMAN", "id": "O95907-1", "name": "Monocarboxylate transporter 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MG-------AGGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYS-----DTAWVSSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLG---LALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCACGAVMRPPPGPGPRPR------------------------------------------------------------------------------------------------------------------------------------------------------------------RDSAGDRAGDAP----------------------GEAEADGAGLQLREASPRVRPRRRLLDLAVCTD------RAFAVYAVTKFLMALGLFVPAILLVNYAKDAGV---PDTDAAFLLSIVGFVDIVARPACG-ALAGL-----ARLRPHV--PYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMVGALQFEVLMA--AVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEII---FYLAGSEVALAGVFMAVATNCCLRCAKAAPS--------------GPGTEGGASDTEDAEAEGDSEPLPVVAE--------------------------EPGNLEALEVLSARGEPTE--PEIEARPRLAAESV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P57787-1", "uniprot_id": "MOT4_MOUSE", "id": "P57787-1", "name": "Monocarboxylate transporter 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGAV----VDEGPTGIKAPDGGWGWAVLFGCFIITGFSYAFPKAVSVFFKELMHEFGIGYS-----DTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLG---LALNFQPSLIMLNRYFNKRRPIANGLAAAGSPVFLCALSPLGQLLQDHYGWRGGFLILGGLLLNCCVCAALMRPLVAPQVGGG------------------------------------------------------------------------------------------------------------------------------------------------------------------TEPRGPQ---------------------------------------------RPPQR-LLDLSVFRD------RGFLIYAVAASIMVLGLFVPPVFVVSYAKDMGV---PDTKAAFLLTILGFIDIFARPTAG-FITGL-----KKVRPYS--VYLFSFAMFFNGFTDLTGSTATDYGGLVVFCIFFGISYGMVGALQFEVLMA--IVGTQKFSSAIGLVLLLEAVAVLIGPPSGGKLLDATKVYKYV---FILAGAEVLTSSLVLLLGNFFCIG-KRKRPE--------------VTEPEEVASEE-KLHKPPVDVGVDS------------------------------REVEHFLKAEPEKNGE---------VVHTPETSV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35910-1", "uniprot_id": "MOT4_RAT", "id": "O35910-1", "name": "Monocarboxylate transporter 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGAV----VDEGPTGIKAPDGGWGWAVLFGCFIITGFSYAFPKAVSVFFKELMHEFGIGYS-----DTAWISSILLAMLYGTGPLCSMCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLG---LALNFQPSLIMLNRYFNKRRPMANGLAAAGSPVFLCALSPLGQLLQDHYGWRGGFLILGGLLLNCCVCAALMRPLVAPQASGG------------------------------------------------------------------------------------------------------------------------------------------------------------------AEPHGPQ---------------------------------------------RPSPR-LLDLSVFRD------RGFLIYAVAASIMVLGLFVPPVFVVSYAKDMGV---PDTKAAFLLTILGFIDIFARPTAG-FITGL-----KKVRPYS--VYLFSFAMFFNGFTDLTGSTASDYGGLVVFCIFFGISYGMVGALQFEVLMA--IVGTQKFSSAIGLVLLLEAVAVLIGPPSGGKLLDATKVYKYV---FILAGAEVLTSSLVLLLGNFFCIG-KRKRPE--------------VTKPEEVASEEEKLHKPPVDVRVDS------------------------------REVEHFLKAEPEKNGE---------VVHTPETSV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15427-1", "uniprot_id": "MOT4_HUMAN", "id": "O15427-1", "name": "Monocarboxylate transporter 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGAV----VDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYS-----DTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLG---LALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAALMRPLVVTAQPG----------------------------------------------------------------------------------------------------------------------------------------------------------------------SGPP---------------------------------------------RPSRR-LLDLSVFRD------RGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGV---PDTKAAFLLTILGFIDIFARPAAG-FVAGL-----GKVRPYS--VYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMA--IVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYV---FILAGAEVLTSSLILLLGNFFCI---RKKPK--------------EPQPEVAAAEEEKLHKPPADSGVDL------------------------------REVEHFLKAEPEKNGE---------VVHTPETSV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q7T3-1", "uniprot_id": "F1Q7T3_DANRE", "id": "F1Q7T3-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGAV----VDTGDSGVKAPDGGWGWAVLFGCFIITGFSYAFPKAVSVFFKELIREFGVGYS-----DTAWISSILLAMLYGTGPLCSILVNRFGCRPVMMVGGLFASLGMVLASFATNIIHIYLCTGVITGLG---LALNFQPSLIMLNRYFSEKRPLANGLAAAGSPVALCCLSPLGQVLQYKYGWRGGFLILGGLLLNCCACGALMRPLLAPKKT--------------------------------------------------------------------------------------------------------------------------------------------------------------------SEVEEKP------------------------------------------KETKPKPK-LLDFTVFKD------RGFLIYTIAASIMVLGLFVPPVFVVSYAKELGN---EDTKSALLLTILGFIDIFARPTSG-IIAGL-----KWVRPRC--VYLFSFAMIFNGIADILGSFAKDYASLVVFCIFFGISYGMVGALQFEVLMA--IVGTEKFSSAIGLVLLVEAIAVLVGPPGAGRLLDATKNYMYV---FMLAGCEVVLSALVLAICNLLFIKRKPQQPD--------------PPAKMEMAITETEMEELNKAPKDDQDNGGGAENEKKQAIEPETKTTSKDEVKELESIEVDSIEVENASKKVSG----PNGVAVEPESSL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BBA0-1", "uniprot_id": "A0A8M2BBA0_DANRE", "id": "A0A8M2BBA0-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGVA----LDDGGCKVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIREFGVGYS-----DTAWISSILLAMLYGTGPLCSILVNRFGCRPVMLVGGLFASLGMILASFATSIIHIYLCTGVITGLG---MALNFQPSLIMLNRYFSEKRPLANGLAAAGSPVALCCLSPLGQVLQYEYGWRGGFLILGGILLNCCACGALMRPLVPPKSSEA------------------------------------------------------------------------------------------------------------------------------------------------------------------PGIENAPDDGD--------------------------------------KTVKPKPK-LLDFSVFRD------RGFLIYTIAASIMVLGLFVPPVFVVSYAKELGN---EDTKSALLLSILGFIDIFARPTCG-IIAGL-----QWVRPRC--VYLFSFALIFNGITDLVGSLSKDYTSLVVFCIFFGISYGMVGALQFEVLMA--VVGTEKFSSAIGLVLMLEAIAVLVGPPSAGRLLDHTKKYMFV---FLLAGIEVVLSALVLAICNFLCIKKKPEAPD--------------AAAVESGEPVEEKNHSSPPATEEPHTPNGNSE-KPKTDLRPE-------NVTEEPTEEETFLKEEDEKEKT---------ITCSAESDL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B5K3-1", "uniprot_id": "A0ACD6B5K3_DANRE", "id": "A0ACD6B5K3-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGIV----EDRETAG--APDGGWGWVVLLGGFVITGFSYAFPKAISVYFKELMHDFGCGYK-----DTAWISSIILAMLYGSGPISSIMVNKFGCRPVMLVGGLLASLGMISASFATSIIHLYITAGVITGLG---LALNFQPSLIMLGAYFDKRRPLANGLAAAGSPVFLSALSPLGQLLLDQYGWRGGFLITGGLLLNCCTCGAVMRPLKLKERKACNQE-------------------------------------------------------------------------------------------------------------------------------------------------------LKEMLPPEAGQENIVCENN--------------------------------------NDKKPSKKKLLDFSVLRD------KGLIIYIIAKFIVVLGLFVPTILLVNYAKDQGV---PDKEAAFLLSIIGFIDIFARPTCG-VVAGL-----KWVRPKM--SYFFSLALLFNGLTDVCSATSTDYKGLIIFCVFFGLSYGMVGALQFEVLMG--IVGTSKFSSALGLVLLFEAVAVLIGPPSAGYLVDKYKNYELI---FYMAGGELITAGIFLALASFCCIS-QKKRKD--------------SPQ-----------------------------------------------------TQQTYVEVNPER------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "G5E8K6-1", "uniprot_id": "MOT6_MOUSE", "id": "G5E8K6-1", "name": "Monocarboxylate transporter 6", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARALEQADGRWAWVVLLSSLVTQALTLGFPTCIGVFFTDLQRDFQASNS-----ETSWFPSILGAMVHGGGPLCSILVKHFGCRVTMMLGGVLASLGMVVSTFSGSLTHLFLTAGVITGLG---MCFSFQSSITVVGLYFVRRRPLANALASMGLSMGVTLWPLLARYLLETLGWRGAFLIFGGILLHCCVCGALLRPVA--TNEVPEP----------------------------------------------------------------------------------------------------------------------------------------------------------------KEDPLLPPKIP---------------------------------TRSCLATCVSTIRYHLAFDILRHN-----MGFCIYVTGVTWMNLGFALPHIFLVPYAMHHGV---DDYWAAMLMSIVGFCNIFLRPMAGLLLAGR-----KSLAAYR--KYLFAVAILINGLTNLICTVSADFRVLLGYCLVYSLSMCGVGILVFQVLMD--IVPMDRFPSALGLFTILCGVTSLISPPLAGLLLDKTNNFSYV---FYMSSGFLVSGSLILGVGFYAAEKKKLKQ-----------------DGQAKMEN----ATSEMTP-------------------------------MHDLTSEDKDSAKKQPYPESIY-----------MTNV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15375-1", "uniprot_id": "MOT6_HUMAN", "id": "O15375-1", "name": "Monocarboxylate transporter 6", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQALERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNS-----ETSWFPSILTAVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLG---MCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVA--TSVAPET----------------------------------------------------------------------------------------------------------------------------------------------------------------KECPPPPPETP---------------------------------ALGCLAACGRTIQRHLAFDILRHN-----TGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSV---DEQQAALLISIIGFSNIFLRPLAG-LMAGR-----PAFASHR--KYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMD--IVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYV---FYMSSFFLISAALFMGGSFYALQKKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKH-----------------------LWGCPASSRTSHEWLLWPKAVL-----------QAKQTALGWNSPT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QAK1-1", "uniprot_id": "A0A8M9QAK1_DANRE", "id": "A0A8M9QAK1-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTEGVEVHQPQPNTTVTRSRASSLQAFENADTASCKSEEPDQEEEEEQSSSTLPEERHCSTGGQANAQLAPDGGWGWVVVAATILVLAMTLAFPSCIGIFYTELQSDFQASNT-----ETSWVPAIMMAVLHACGPICSVLVERCGCRATIIIGGILSGLGMAASSFAQTMVELYITAGIITGMG---FSLCFQPSITMVGHYFVRRRAFANALSSTGTALGLSILPLLANYLLRNFGWRGSFLVLGGVLLNCCVCGAVMRPLAAKPKMETRT----------------------------------------------------------------------------------------------------------------------------------------------------------------KETDNHHLKTNC----------------------LSVHQGLKGRLRATLSTIMTFLRRHMAFDLLCSN-----PYFCAYALGVSWMMLGFVVPLVYLVPYATAYGM---EQDQAALLMAILGLINIIVRPATA-LVFGL-----PRFRGSHNFAYLFAIAVVINGLSNCVCGIGTSFLVLLVYVILFGFSMSLVGSLLFTVLMD--TVEMSRFPSALGLISIMESIMLLLGPPLAGILVDSTGQYIYV---FFACSVTGSTAGLFIMLSFYWLDRRRDREQ--------------VKSSSAHQDP------HSLKP-------------------------------SLKMTIDCEYSPVPLHSKNTRD-----------TETDV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7FB53-1", "uniprot_id": "E7FB53_DANRE", "id": "E7FB53-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPQQPS--------------SMEEQSGELC---EPESEELEKQGPGPP------SNANAPDSYDAPDGGWGWVVLLATIIVLALTLAFPSCIIIFYLDLQKEFEATNS-----QTSWVPSIMTAVLHAGGPLCSVLVDRFGCRATVMFGGVLSGFGMAVSSFSHSIVDLYITAGVITGLG---FCFSFQPAVTILGHYFVRRRPFANAMSSTGTALGLSTLPFLCDFLKIELGWRGSFLVLGAVLLNCCVCGAVMRPIR--PRKPRKT----------------------------------------------------------------------------------------------------------------------------------------------------------------NEINNSPKTS-----------------------------DKKGCMLGICQSLASSLRQQMAFDLFCSN-----TRFRVFSLGITWMMLGFVVPLIYLVPYASADDM---DPSRAALLLSILGFVNIFVRPPVG-VLFSL-----PWFKGRH--IYVFSAALLINGLSNSICCISASFPVLLVYVLTYGLSMSVVGSLMFTVLMD--TVEMSRFPSALGLLSIMESVTLLIGPPLAGFLVDRTQLYTYV---FMACTIIVVLSALFLMFTFYWLDSR----------------------DAAKKD-------SPAKP-------------------------------AINISTDCQYSSVPIDGDKTNK-----------PSSETENTTCV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8CE94-1", "uniprot_id": "MOT13_MOUSE", "id": "Q8CE94-1", "name": "Monocarboxylate transporter 13", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVRRAEPPDGGWGWMVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAA-----RVSWIASIGIAVQQFGSPIGSALSTKLGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSG---WALTFTPTMACLSRYFSQRRSLAMGLALTGVGISSFAFAPLFQWLINNYAWRGALLLVSALSLHLMACGALLRPLSLTEDAAVG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPGAQITS-LLRH------GPFLRYTAALTLINTGFFIPYVHLVAHLQDLGW---DPLPAAFLLSVAAVSDLVGRVASGWLGDAVPG---PVARLLMLWTTLTGV---SLALFPVAQAS----STLVVLAVAYGFTSGALTPVAFSVLPE--LVGTGRIYCGMGLVQMIESIGGLLGAPLSGYLRDVTGNYTAS---FVVAGAFLLAGSGVLLTLP-HFFSCISVS----------------------TSRPQDLVIEASDT-----------------------------------KIPLPKEEGLGEN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66HE2-1", "uniprot_id": "MOT13_RAT", "id": "Q66HE2-1", "name": "Monocarboxylate transporter 13", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVHRTEPPDGGWGWMVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAA-----RVSWIASIGIAVQQFGSPIGSALSTKLGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSG---WALTFTPTLACLSRYFSQRRSLAMGLALTGVGISSFAFAPLFQWLLNNYAWRGALLLVSALSLHLVACGALLRPLSLTEDTAVG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPWAQITS-LLCH------GPFLRYTVALTLINTGYFIPYVHLVAHLQDLGW---DPLPAAFLLSVAAISDLVGRVASGWLGDAVPG---PVARLLMLWTTLTGV---SLALFPVAQAS----TTLVVLAVAYGFTSGALTPVAFSVIPE--LVGTGRIYCGLGLVQMIESVGGLLGAPLSGYLRDVTGNYTAS---FVVAGAFLLAGSGVLITLP-HFFSCISLS----------------------TSRPQDLVIEAPDT-----------------------------------KIPLPKEEGLGEN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7RTY0-1", "uniprot_id": "MOT13_HUMAN", "id": "Q7RTY0-1", "name": "Monocarboxylate transporter 13", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARRTEPPDGGWGWVVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAA-----RVSWIASIGIAVQQFGSPVGSALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSG---WALTFAPTLACLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLHLVACGALLRPPSLAEDPAVG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPRAQLTS-LLHH------GPFLRYTVALTLINTGYFIPYLHLVAHLQDLDW---DPLPAAFLLSVVAISDLVGRVVSGWLGDAVPG---PVTRLLMLWTTLTGV---SLALFPVAQAP----TALVALAVAYGFTSGALAPLAFSVLPE--LIGTRRIYCGLGLLQMIESIGGLLGPPLSGYLRDVTGNYTAS---FVVAGAFLLSGSGILLTLP-HFF-CFSTT----------------------TSGPQDLVTEALDT-----------------------------------KVPLPKE-GLEED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5NC32-1", "uniprot_id": "MOT11_MOUSE", "id": "Q5NC32-1", "name": "Monocarboxylate transporter 11", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTPKPAGPPDGGWGWVVAAAAFAVNGLSYGLLRSLGLALPDLAEHFERSAQ-----DTAWVSALALAVQQAASPVGSALSTRWGARPVVMVGGVLTSLGLVFSAFARSLLHLYLGLGLLAGSG---WALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQFLLDTFGWRGALLLLGAVTLHLTPCGALLRPLALSGDPLAPP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RTPLAALGLGLFKR------RAFSVFALGTALIGGGYFVPYVHLGPHALDQGM---GGYGAALVVAVAAVGDACARLASGWLADQGWV---PLPRLLVVFGSLTGLGVLAMGLVPTVGTEEGWGAPLLAAAGAYGLSAGSYAPLVFGVLPG--LVGIGGVVQATGLVMMLMSLGGLLGPPLSGFLRDKTGDFSAS---FLVCSSFILSGSFIYMGLPRALPSCRPASPP--------------------ATPPPERGELLPVP-----------------------------------QVSLLSAGGTGSIRDTTC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ARJ5-1", "uniprot_id": "A0A8I6ARJ5_RAT", "id": "A0A8I6ARJ5-1", "name": "Monocarboxylate transporter 11", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRGQRAGQGLQPGSSCVRSRRQVRGREPRGAERRGERRGAATRHPHSPQFPIQGWGLCVDNSIPVGLGVRSRPGLGGLAVSRSPALGTHPHPHPVSQVARAPVVISVYRRERSKLGSISALASCSAEPCLPGKRGENSAEPTLALSLPPTPGEVGPGSRAHAPGDVPTLGEQPEAGSQGRQLPSRGPGVETSFTGVSPPQQTAMTPKPAGPPDGGWGWVVAAAAFAVNGLSYGLLRSLGLALPDLAEHFERSAQ-----DTAWVSALALAVQQAASPVGSALSTRWGARPVVMVGGVLTSLGLVFSAFARSLLHLYLGLGLLAGSG---WALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQFLLDTFGWRGALLLLGAVTLHLTPCGALLRPLALSGDPLAPP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RTPLAALGLGLFRR------PAFSVFALGTALIGGGYFVPYVHLGPHALDQGM---GGYGAALVVAVAAVGDASARLVSGWLADQGWV---PLPRLLVVFGSLTGLGVLAVGLVPTVGTEEGWGAPLLAAAGAYGLSAGSYAPLVFGVLPG--LVGIGGVVQATGLVMMLMSLGGLLGPPLSGFLRDKTGDFSAS---FLVCSSFILSGSFIYMGLPRALPSCRPASPP--------------------ATPPPERGELLPVP-----------------------------------QVSLLSTGGSSSIRDTTC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NCK7-1", "uniprot_id": "MOT11_HUMAN", "id": "Q8NCK7-1", "name": "Monocarboxylate transporter 11", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTPQPAGPPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQ-----DTAWISALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFG---WALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGALLLPLVLPGDPPAPP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSPLAALGLSLFTR------RAFSIFALGTALVGGGYFVPYVHLAPHALDRGL---GGYGAALVVAVAAMGDAGARLVCGWLADQGWV---PLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPG--LVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTAS---FLLSGSLILSGSFIYIGLPRALPSCGPASPP--------------------ATPPPETGELLPAP-----------------------------------QAVLLSPGGPGSTLDTTC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BGC3-1", "uniprot_id": "MOT12_MOUSE", "id": "Q8BGC3-1", "name": "Monocarboxylate transporter 12", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTKITRVSLASPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDYS-----QTAWIHSIVDCMTMLCAPLGSVVSNQLSCQAGIMLGGLLASTGFILGSFATSLKHLYLSLGVLTGLG---FALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDRSVPE--------------------------------------------------------------------------------------------------------------------------------------------------------------KNHNRESQRED--------------------------------CKQASPYSPLTKECTETRLCCSLQQEYGFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGV---SHHQAAFLMSILGVIDIVGNITFGWLTDRRCL---KNYRYVC-----YLFAVALDGLCYLCLPMLQTFPLLVPFSCTFGYFDGAYVTLIPVVTAE--IVGTTSLSSALGVVYFLHAVPYLVSPPIAGWLVDTTGSYTAA---FLLCGFAMIFSSILLGFVRIVKRMKRTQVPFPVK------------DSDPKLQLWTNGSVAYSVARELDQ------------------------------KDEEPLPKARSGCNLT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A734-1", "uniprot_id": "MOT12_RAT", "id": "D4A734-1", "name": "Monocarboxylate transporter 12", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTKITRVGSASPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDYS-----QTAWIHSIVDCMTMLCAPLGSVVSNQLSCQAGIMLGGLLASTGLILGSFATSLKHLYLSLGVLTGLG---FALCYSPAIAMVGKYFSRRKAFAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDPSGPE--------------------------------------------------------------------------------------------------------------------------------------------------------------KSHDRDAQRED--------------------------------CKQASPYSPLTKEWTETRLCCSLQQGYGFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGV---SHHQAAFLMSILGVIDIVGNITFGWLTDRRCL---KNYRYVC-----YLFAVALDGLCYLCLPMLQSFPLLVPFSCTFGYFDGAYVTLIPVVTAE--IVGTTSLSSALGVVYFLHAVPYLVSPPIAGWLVDTTGSYTAA---FLLCGFAMIFSSILLGFAKIAKRMKRTQVPFLVK------------DSDPKLHLWTNGSVAYSIAKELDQ------------------------------KDEESLAKARTGCNLT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZSM3-1", "uniprot_id": "MOT12_HUMAN", "id": "Q6ZSM3-1", "name": "Monocarboxylate transporter 12", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSGSHWTANSSKIITWLLEQPGKEEKRKTMAKVNRARSTSPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYA-----QTAWIHSIVDCVTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTGLG---FALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDHTTPE--------------------------------------------------------------------------------------------------------------------------------------------------------------QNHVCRTQKED--------------------------------IKRVSPYSSLTKEWAQTCLCCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGV---SHQQAAFLMSILGVIDIIGNITFGWLTDRRCL---KNYQYVC-----YLFAVGMDGLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTTE--IVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAA---FLLCGFSMIFSSVLLGFARLIKRMRKTQLQFIAK------------ESDPKLQLWTNGSVAYSVARELDQ------------------------------KHGEPVATAVPGYSLT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R0M8-1", "uniprot_id": "MOT5_MOUSE", "id": "Q8R0M8-1", "name": "Probable monocarboxylate transporter 5", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVKKEKTPSPYTKPLDGGWGWMVVLHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSE-----QIGWIGSIMSSLRFSAGPLAAIICDVLGEKATSILGTFLVSGGYVISSWATGIPFLCVTMGLLPGLG---SAFLYQVAAVVITKYFKKRLGLSTAIARSG-MGLTFLLAPFTKFLIDLYDWTGALILFGAIILNLVPSSMLLRPIHSQS----NNNSDI------------------------------------------------------------------------------------------------------------------ENKG-----SILSATEPEAS--YKTETSKCKETQEPFIKDSTMKKSEQPTTTLT------VLGNQSEEFSNRPHRN-RPLLMSNGKSHKKKFVSWNCKQKLLDISLFRN------PFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGI---DVMDASYLVSVAGITETVSQLISGWIADQN------WIKKYQ----YHKSYLILCGVTNLLAPLATTFPLLMAYTILFAIFAGGYLALILPVLVD--LSKNSRVHKFLGYASFFAGIAVLSGPPIAGWIYDYTQTYTGS---FYFSGTCYILSSVSLFFVPLAERWKRKQSDLLR------------------------------------------------------------------TTIK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LFB5-1", "uniprot_id": "A0ABK0LFB5_RAT", "id": "A0ABK0LFB5-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKKREEKPSPYTKPLDGGWGWMVVLHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSE-----QIGWIGSIMSSLRFSAGPLAAIICDIFGEKTTSILGTFLVSGGYLISSWATGIPFLCVTMGLLPGLG---SAFLYQVAAVVITKYFKKRLGLSTAIARSG-MGLTFLLAPFTKLLIDLYDWTGALILFGAIALNLVPSSMLLRPVHIQS----DSNSDI------------------------------------------------------------------------------------------------------------------KNKG-----SILSATGPELS--HKTETPNRNKAQESLIKDSAVKKSGQPTTTLT------VLENQIEEISTRPHRN-RPLLMSNDKTYKKKFVSWNCKEKLLDISLFRN------PFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGI---DIMDASYLVSVAGITETVSQLISGWIADQN------WIKKYQ----YHKAYLILCGVTNLLAPLATTFPLLMAYTIFFAIFAGGYLALILPVLVD--LSKNSRVHRFLGYASFFAGMAVLSGPPIAGSHVTYAGLKLTT---LEDAG---FELLILLCLSPKCWNYRHVPPFLAS------------------------------------------------------------------ISFPIFFNEKE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15374-1", "uniprot_id": "MOT5_HUMAN", "id": "O15374-1", "name": "Probable monocarboxylate transporter 5", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKREGKVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSE-----QIGWIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLG---SAFLYQVAAVVTTKYFKKRLALSTAIARSG-MGLTFLLAPFTKFLIDLYDWTGALILFGAIALNLVPSSMLLRPIHIKS----ENNSGI------------------------------------------------------------------------------------------------------------------KDKG-----SSLSAHGPEA---HATET-HCHETEESTIKDSTTQKAGLPSKNLT------VSQNQSEEFYNGPNRN-RLLLKSDEES--DKVISWSCKQ-LFDISLFRN------PFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGI---DIMDASYLVSVAGILETVSQIISGWVADQN------WIKKYH----YHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPVLVD--LCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGS---FYFSGICYLLSSVSFFFVPLAERWKNSLT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QW16-1", "uniprot_id": "F1QW16_DANRE", "id": "F1QW16-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLPKEQHSDGKTAKTPCSELKAKVMKKEKKKVVYREPPDGGWGWMVVLHCFLVNVLVMGTLKTFGIFFVALQDEFGGSSE-----SISWIGSIMSSLRLSGGPLASVACAKLGNRVTSIVGALFVSAGFLFSIFATSVTYLYISMGLVVGLG---FALLYQATSVVIVTYFRKRLATAYSIGRSG-MGLTFALAPFTQLLLDQYAWQGALLILGGLMLNLVASGMLLRPINIRHPASPISNSTI------------------------------------------------------------------------------------------------------------------HKTEKDPLKNNMNGNTPVANGTSKSDSSPPIHKDTLIIKNPVHEQNSLPHLDLKKPTQNGVNGTDSSQTKTSPEMNGVSPVDSLLENGRTENVPENSPK-VLDFSLLKN------PFFCIYTWSLVFSQLAYFIPYFHLSARARNLGI---DPMDASFIISVAGITETVAQLASGWVTDRN------LVHKYH----YHKAYLILCGVVNLLSPLATSYILLMVYAVFFAIFCGGYMALLLPVLVD--LVGADKLNNSMGFSMFFVGLGCLTGPPLAGFLYDYTQTYDCS---FYLAGVCYLLSSISLFLEPLARRWQARKERLET------------------------------------------------------------------LNQELMWSNGCFCPAPQRNGVV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8K1C7-1", "uniprot_id": "MOT14_MOUSE", "id": "Q8K1C7-1", "name": "Monocarboxylate transporter 14", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYTSHEDIGYDLEDDRKAKNKKTLKPHPDIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRG-----LTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVQSLFITFGVAAGLG---SGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMFIQGALSLNLCVCGALMRPLSPEKLENCPEAEEP------------------------------------------------------------------------------------------------------------------CALPAYSTESVKSGGPLGMAEEQDRR----------PGNEEMVCDLQTQECQGQTHPRKNV----------CAFR--VLKTVSQLTVQVRRGFRDWHSGYFGTASLFTN------RMFVAFIFWALFAYSSFVIPFIHLPEIVSLYNLS--EQNDTFPLTSIIAILHIFGKVILGAVADLP------CISVWN----VFLIANFTLVLSIFLLPLMHTYASLAVICALIGFSSGYFSLMPVVTEDL---VGTEHLANAYGIIICANGISALLGPPFAGWIFDITQKYDFS---FYICGLLYMVG--ILFLLIQPCIQ--------------------------------------------------------------------------MIDQSRRKCIEGAHV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A0E5-1", "uniprot_id": "D4A0E5_RAT", "id": "D4A0E5-1", "name": "Monocarboxylate transporter 14", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYTSHEDIGYDLEDDRKAKNKKTLKPHPDIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRG-----LTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVQSLFITFGVAAGLG---SGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMFIQGALSLNLCVCGALMRPLSPEKVENCSGAEEP------------------------------------------------------------------------------------------------------------------CALPAYSTESVKSGGPLDMTEEQDRR----------PGNEETVCDLQTQELQGQTHPRKNV----------CAFR--VLKTVGQLTVRVQRGFRDWHSGYFGTASLFTN------RMFVAFIFWALFAYSSFVIPFIHLPEIVSLYNLS--EQNDAFPLTSIIAILHIFGKVILGAVADLP------CISVWN----VFLIANFTLVLSIFLLPLMHTYASLAVICALIGFSSGYFSLMPVVTEDL---VGTEHLANAYGIIICANGISALLGPPFAGWIFDITQKYDFS---FYICGLLYMVG--ILFLLIQPCIQ--------------------------------------------------------------------------MTEQSGRKCMDSAHV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7RTX9-1", "uniprot_id": "MOT14_HUMAN", "id": "Q7RTX9-1", "name": "Monocarboxylate transporter 14", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYTSHEDIGYDFEDG--PKDKKTLKPHPNIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRG-----LTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGVAAGLG---SGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMLIQGAVSLNLCVCGALMRPLSPGKNPNDPGEKDV------------------------------------------------------------------------------------------------------------------RGLPAHSTESVKSTGQQGRTEEKDGG----------LGNEETLCDLQAQECPDQAGHRKNM----------CALR--ILKTVSWLTMRVRKGFEDWYSGYFGTASLFTN------RMFVAFIFWALFAYSSFVIPFIHLPEIVNLYNLS--EQNDVFPLTSIIAIVHIFGKVILGVIADLP------CISVWN----VFLLANFTLVLSIFILPLMHTYAGLAVICALIGFSSGYFSLMPVVTEDL---VGIEHLANAYGIIICANGISALLGPPFAGWIYDITQKYDFS---FYICGLLYMIG--ILFLLIQPCIR--------------------------------------------------------------------------IIEQSRRKYMDGAHV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TM99-1", "uniprot_id": "MOT9_MOUSE", "id": "Q7TM99-1", "name": "Monocarboxylate transporter 9", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEFQKSP---DGGWGWVIVVVSFFTQFLSYGSPLAVGVLYVEWLDAFGEGKG-----KTAWVGSLASGVGLLASPVCSLFVSSFGARPVTIFSGFLVAGGLMLSSLAPNIYFLFFSYGIVVGLG---CGLLYTATVTITCQYFDSRRGLALGLISTGSSVGLFIYAALQRMLIEFYGLDGCLLIVGALALNILACGSLMRPLQTSDCPFPEKTAPE------------------------------------------------------------------------------------------------------------------NVPDRYSMYNEKEKNPEETMNFQDKGYSSEDKC---LPNGDWGRETSLPKSLAIAAHTKEP----------ETYKKKVVEQTNFCKQLAKRKWQLYRNYCGETASLFKN------KVFSALFIAILLFDIGGFPPSLLMEDVARSYHVR--EEDLTMPLISIFGIMTAVGKLLLGILADFK------WINTLY----LYVATLIITGLALCAIPFAKSYVTLAILSGILGFLTGNWSIFPYVTTKT---VGIDKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIA---FYFSGFCVLLGGFILLLAILPCWD--------------------------------------------------------------------------MCNKKLPKPAVPTTFFYKVASNV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RCI4-1", "uniprot_id": "MOT9_RAT", "id": "M0RCI4-1", "name": "Monocarboxylate transporter 9", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGFQKSP---DGGWGWVIVVVSFFTQFLCYGSPLAVGVLYVEWLDAFGEGKG-----KTAWVGSLASGVGLLASPVCSLFVSSFGARPVTIFSGFLVAGGLMLSSLAPNIYFLFFSYGIVVGLG---CGLLYTATVTITCQYFDSRRGLALGLISTGSSVGLFIYAALQRMLIEFYGLDGCLLIVGALALNILACGSLMRPLQTSDCPFPEKIAPE------------------------------------------------------------------------------------------------------------------NVPDRYSIYNEKEKNQEETMTFQDKGYSNEDKC---LPNGDWGRETSLPKNPTGAAHTKEP----------EPYKKKVVEQTNFCKQLAKRKWQVYRNYCGETASLFKN------KVFSALFVAILLFDIGGFPPSLLMEDVARSYHVR--EEDLTIPLISIFGIMTAVGKLLLGILADFK------WVNTLY----LYVATLIITGLALCAIPLAKSYVTLAILSGILGFLTGNWSIFPYVTTKT---VGIDKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIA---FYFSGFCVLLGGFILLLAILPCWG--------------------------------------------------------------------------MCNQRLPKPAAPTTFFYKVASNV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7RTY1-1", "uniprot_id": "MOT9_HUMAN", "id": "Q7RTY1-1", "name": "Monocarboxylate transporter 9", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELKKSP---DGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKG-----KTAWVGSLASGVGLLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLG---CGLLYTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGSLMRPLQSSDCPLPKKIAPE------------------------------------------------------------------------------------------------------------------DLPDKYSIYNEKGKNLEENINILDKSYSSEEKCRITLANGDWKQDSLLHKNPT-VTHTKEP----------ETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVALFKN------KVFSALFIAILLFDIGGFPPSLLMEDVARSSNVK--EEEFIMPLISIIGIMTAVGKLLLGILADFK------WINTLY----LYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIFPYVTTKT---VGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIA---FYFSGFCVLLGGFILLLAALPSWD--------------------------------------------------------------------------TCNKQLPKP-APTTFLYKVASNV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P097-1", "uniprot_id": "A0A8M9P097_DANRE", "id": "A0A8M9P097-1", "name": "Monocarboxylate transporter 9", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAVKSESTLDGGWGWMIVVASFMAQFLSFGSPQSVGVLYPEWLSAFQEGKG-----MTAWVGSMVSGVALITSPVCSACVDNFGARPVTIFSGVMVAGGLMLSAFAPNISFLIFSYGIVVGMG---CGLVYAATLTITCQYFDKRRGLALGIVTTGTSVGGFIYATLQNELIELFGLEGCLLIIGALALNLMACAGPMRPLNLPGYYLKQRAALQ------------------------------------------------------------------------------------------------------------------RTEDPEPLYSKP------TAIIIESGSDLKTKPG--LAENTTTVKLLINKDPT---ELQDS----------EGERKVHILSSSIIARAIKKWMRPYGQYFCETVELLQD------RVFMAFCIAMFLFSLGAFPPVLFMEDVAQSEGLI--DGIALIPLVSIVAMTTGIGKLILGVLADMR------WVNSLY----LYALTLIGSGTALLLIPVSKSYLGLQILSAAVGFFSGNWSLTSYITTKI---VGIERLGQAHGILMCFGGFGIALGPPVVGWFFDWTQSYDLA---FYLSGTCVLVSGVFLFLAALPCWNRTAQEGNS------------------------------------------------------------------QAEEDVNTSQQHHSFDCDKVASVA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWK0-1", "uniprot_id": "Q9VWK0_DROME", "id": "Q9VWK0-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKKVYQDTTRPLPRVSRARYYN---------------KHDKSDLGDDFVAPDAGWAWIVCVAAGVSNLSIYPCLQQFGFLFRERLSDLGMSSS-----QITAIINANPAVSACTGLLNGPMFRRFTFRQVAMAGSLLISGSLILTAFCETFLSYMVAYALLFGFG---MGISVSASSLAINTYFQKKRRRAAGFSWTITGLGPIFLPHLVTFLLTIYGVQGTTLLFAAISLHSFVCALIYQPVRYHVKPPVEQ--------------------------------------------------LADQEQQAEALCAHCSWQQKREPGGIFSSQYLCQDDDAQRPGYEICEPGTPMLSRANDGWYGSRLSLTSGRLRFRTISSSKDLEQTQRLHCPISEEQNHESDEFLRPNNFRRERVESNLEAKLCCQCSAKREEHNNNRKEKEAEAEEAGMESAPLHDPQMSFLAKVVTFFDLDLLRD------FTFVNLVAGLTIINFGELNFSILTP-FILVDFGF--DTPQITLAMSLLAGLDITMRFMVPFLTEKIPWDNRV----------FFLIGVVGIALGRTVVACTRSYSLILCSFVWIGLCKGVRTIFWPLIIPG--YVPLNRLPGASGLQLLISGLFTLIGGPFVGLVRDRYD-YSVT---LHCLNMMSFVAATSWSLEALIRRHRRKQRLVNS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWJ0-1", "uniprot_id": "Q9VWJ0_DROME", "id": "Q9VWJ0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDNGNNHNNNNNNNNDEALRLRLPEEQAEQLLPKNGSAGQTKIAPPTHTHSIAAASVPQKVPAKKKRDKSDLGEDFVAPDGGWGWLVSVASGVNILVTFALAQQFGILFRDRMAGLGISSS-----ELTTIINTQIAVSAFTGLLNGPLFRRYTYRVVALVGSVLTFLGLFWMVFADTFAVYIMSFSILYGFG---RGLTVSASSLAVNTYFKVKRRTATAFQFGVAGLGPIVCPYFATYMLYEFGVQGTTLLFAGASLHTIACSLIYQPVKWHVVK---------------------------------------------------------RDRDAEALQQVQPLAERED-----------QDEDIIKN---VVEPETPVLPRANDGWFGSRASLNSVGTRNRLNTWEK---SDSNGHVELKRLSSKDSN---PGRQLRSISVSHSIKEEEATGYNSDHEVQHTELTEKEKQELED--EKERQRRKKLPFYMKVVIFFDMDLLRD------ITYVNLAVGITLINFVEINFAILTP-FILSDLGF--NKDQIALAMSTLGFFDLVVRFLIPLITAKINLSNRT----------FFVVGILGMCIGRMFLSMTSNFYVMMAIFLWLGLNKAFRTVFWSLIIPS--YVPLKRLPAAAGLQLLMSGTFSMIFGPLIGLIRDHTS-YAVT---LNLLNALCVMAFAGWYLEDFIRARSRKSPPVKSIN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWJ1-1", "uniprot_id": "Q9VWJ1_DROME", "id": "Q9VWJ1-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASKQPRKVAPDGGWGWVACFGVSLVNLATRSIEPSFGLLFGDTLKELNVGTT-----GAAVIISALDVCMNFSGLFVGPLLKEFSYRKVAIAGSLLCGLGLALTSPATSMAHILSTYSVINGIG---VGLSTSAAFVALNHYFKHKRGQAVGLSMAGTAMGMLIMPQLVRILLEAYDFRGAVLLLAGVALNATVGSVLLQPVKWHMKEEFDDEELMCISALPTPQPQLTVGGAGGAASAGAPVFKVIKEDGNEEDALPEMNTLLFHKPHPHQHSMRKNYSEMAMNTMNGSRLGIPKRPTFPRIMSLAGVQSAAHGAGGDSGGYTSQAEVNATQLRCRKASVTSNL-SYMDFTGSILQVHLNTGDDEFEQNDRELRRVGTATGSIVLGGHRDSFIKMKPTELDKQAEAAAALDEEAKKKAKKPGFWRRFADLLDIDMLKD------KMFLNLLFGLSIFYVAEMNFKMVTP-FFFANLGY--QKTDVAFCLSITAITDIAARIVLPPIFDRTTIKKRT----------IFLVSIIFVALTRSIMAEQTEWTQLMIWLSICGFFRGSALSNFTLTVSE--YCSLEKLPSAFGWHLVGKALFVITFGPLIGLIRDVTDSYPIC---IHTQSVCIMICATAWGIEYLVEYIQSRRRTADAAQ---------------------------------------------------------------LPTQDVGATTTATSDQNDVKL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E960-1", "uniprot_id": "Q0E960_DROME", "id": "Q0E960-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDVQSSRVVPDGGYGWIVVAAVALINMTNQSILSVFGQLFVGELQKMQEDTF-----TAALITNLNSLALNFSGLFIGPAIKSFKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFG---LGLISPSTFMAINSYFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFGAAFLKPLN-----------------------------------------------------------------PPAKHNNRK----------------------HIRLLTEADGEK----------------------------------------TSPLQVVIVPTNQSKIERSPPNVDTLCSRMG-------------------------------------------QRLVQAMDLELLKD------LVFWSIIVGMALVYTATINFTMIFPGFLGQTAQL--NSQMVAFCMSLVAGADIVFRLLLPIVTDHLRIPYRV----------VFLIGIVGLFVARCVLAENQTLPVIITMSVLTGMMKSATVINNNLTISA--HCRSEKLAGGLGLSMMSKGVIVITVGQLLGWVRDYADSYLIC---LYAQGVILLVVVLVWTPEILYRHR--RQRCATNKS---------------------------------------------------------------METQSIDAAEVAKLNS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JUR0-1", "uniprot_id": "A8JUR0_DROME", "id": "A8JUR0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQTGIVWLTIEHRLQSRPAYQMKKSKSYTLEAPDGGWGILVCIGMALPFTSALAALPSFGLVFGEFLKSIGAETS-----AMAIITSAFFSSMSFAGLFSGSLFQRFGMRQVGVTGGILYFLGTGMQLFATSTLHLIMAFSVVQGFA---FGLMVPTCYTTFNHYFVKNRVMWMSFAQTLIGLGSMLYPIVMQKLMSWYGFRGCLLILTGLNAHAVFGMLVMHPVEWHMRRVPIQPEEQ------------------------------------------------------------------------------------------------------EELKELSPTVVIRVQPETPLKATREEPNFHTADPGARKLSHAEEQMLKVLSSRASSITSLGNWSGPVVVSDASPQMMHSLQTSRRPSTIAGASGAVAPAHATKKSWVRTIVDFLDLTLLKK------PIFVNIVLGITFALYSDITFFTMQPVYLFELGY---SRPDTATIIAIGAAADLASRIFLAITAVCIQ------VPSRY----IYLAGAVFTVFARFAFNGITQFVGMACITAVIGFLRTWLHVPLPLVFAD--YLPKERFATGYGLFMFIQGNAMFLIGPIVGFIRDKTRDYIFV---FHILNGFMILCAAPWVLEVLIVKFRRRNKIE---------------------------------------------------------------------RNNVDHEDVDNQGRSAMVQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4LFF4-1", "uniprot_id": "A0A0B4LFF4_DROME", "id": "A0A0B4LFF4-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------MSRNRRRSFPSSQYEDKTAAAQPSGSSLRSQSLSRLDISVQNSSIYYNDTRNTRPQMVSVAVGTVSTDILNGRTSFLSLSQSHGSEVDLPSFYESFNPTFLPKLPIRRFPHMLVGASNEPEISKNQPAIPPSRPIEPISEVPFVEPAFEKKYSRTRGFSKELSTHRDNENEYIESTDEVSQMLSFTSYTDEYDRAEPLITKTQKFYKKRSPLIPKYDSEDSYVVPKETDQQESGLSFNVTTVQLADTASPESFSEYDGNRTRKQSFDMESKNSKESFDFSRGGRRLGSGMVFIYMVIPPDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSIS-----SVSFVASVQIGCYFTSGAFSAVLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGITLSMIWASSQLIVGYYFERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAYVEVAPTQVGMYHLPGSSDTSSDEYYG-----------------------------------------------------------------NFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCPSCSNCCWRRRKKSQNADEQNLLIRPAPLEREDLFYTGPAEYEKPHSKENVDGKEFLLMGSDKNTQQVNYGIKNIRVDDEPDRISRVHRERRWSNENQKKQNSCRNSRFMLTVLKLFDYRLLKQFEFKILVASAFLFPMGFNIPFVYSSARTTIPVEYARMIGPIIGISNLVMRNILGILAYKRR----SWTLG------LCGCGLIFGGVSVLISAFYGENLIWFQFLYGFSYAVAPAVYSTLRGLIYVKYLGLSKLTNAFGITSLAMGMGAFIGTTIAGKLIGITGNYSAA---FCFAGLCLIVSGFLKLLLPLLIKCRNRMAQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQU7-1", "uniprot_id": "Q9VQU7_DROME", "id": "Q9VQU7-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "MVIQCTCDCNCSDSRDNRSVISCLLPGRSQPYKLGSSFGGDDMEQRIPYYRRLSNTSSALYGSCPQLLPSSSSTNNRHSWLRIPKNPQENPSENPSENPRQYSSLVRPKQRSPVLCNKCALXRRYNLSCEHPKQTAGHPGSGNTDQTAQTKPDKDSTNQRYLCYECRFNNQPLAWWVSCPRLSYLPAEQTKMQSTTTPTRHCHGGVGTQTTLPQTTSTPPTLPRFPSKRHCDNFGSYATLPTIEHQMTMPMMPHCSRHGGGGGGGVVGVGGLGGAVGSGMPSVMPAPPPPRYANPNINGCCYMYNPMPPAHQSHHQHDHHHAQQHHPVAQHQHHPHQYGPQYCLCDNWYHQPPPTQQQQHHHQQRAKNLMANGGCYFGYEANHHPSLHATTPHPSHITDEEDSAFPGLADREFHLLHRNIPALRRTGVDTTRIRQYFYPDGGWGWIICGVSFLVHILTTGLQLSYGLLWFYAVQYLHNTSG------IELLGALSWSVSMVATSFVVSLCRKRSIRLLSIVGGLVMPLGILFTSFATEFGQVVFSYGIVFGVG---VAMVREASTVMLGNYFKRRRQFVEMVAMSGEGVGIALFSVILKEGVGKAGWRLGLQIVAALTALSFFMGLMYRPASLYHPQRRAIQHLK-----------------------------------------------------------------------------------------------------------------------------------------------------------NQRKKMREKKP-----------------------------------ILSQDVESTPKYFFLDISSLKS------VTVKILLMTSSVASFGIYTPMFLMALNAAEQGS---DVQELVLLQTFLGISMALGVVIAGALLRRCFVIRHFVINTKI----VTQLFLSIVALAILFLSFVMGYTGLCILSWLYGIGLGGFQYSLKILALER--IKLKHFSKAWGFIRGVESVPVLISVPLTSFLNDYSLKYGRAG--YYICSAAAAISGIIIFFISEPQQQHQQQQQQLHHHYQQRNGHLATPTLMRHASARQHRPHLPMDYGYGEYPAPDLLSRSCISLNQMEPYLQANFCQRHMLQQQQQQQQQQQHSHLQQLACHNLDLQPHQGREAYQLGQGSIGAKMGKRLQRSLSFIQQHSNCCDGQMYCSWHSTYELGCHKSNKNPGSADRQPLICTCSSPNRNPVTYGTHGPTGPPGPTGPPGPPSSTRSRSVPEGLSTMSQQCNCRQGPATFAAPTREFIYVPHAYASLQRTPHRHSQGAGSGPGPGNSALRNNPQCRLKRSQSLCRPNAVQFVEQITTSV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53918-1", "uniprot_id": "ESBP6_YEAST", "id": "P53918-1", "name": "Uncharacterized transporter ESBP6", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTHSNDYFSASSGMVSETSSEVSSINSSQPVSFSKASIAAPVPCSDLHSTKSNDASRKLSISRTLTNRLNDIKKAVDDDNLQTEENSADVNKILESRFDVADAIRLQHNESVQSKLNIPVTHTTTAGASLSAPSSSAFSASSIQNDTTEHKASMDSKLMRNRLYPASTKHSGKDLEAQGITEFEPDEPTVKKVFTNKSTGQLELPPDGGYGWVVTFCVFLTMFSTWGCNASFGVDLAYYLNHDTYPGAS--KYDYALIAGLTVFLGQLLSPLVMALMRIIGLRTTMLFGDAVMLAAYLLASFTTKLWQLYVTQGFMVGCS---ISLIFVPATTVLPGWFLKKRAVAMGVSLLGTGAGGVVYGLATNKMLSDFGNTRWCLRIIGISCSISVLVAIALLKERNPTPAIG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKSPRAMFEQLKAMFSLKVITK------PFVVLIALWFMFALFAYNMMVFTLSSYAISKGLS---SHDASTLTAILNGSQSIGRPLMGLAGDKFG--------RAN---VTIVLTTLLTIYMFAFWIPAHTFVQLIFFSILVGSCVGVANVMNTVLIAD--MVKPEEFLPAWAFVNYCGAPFLLVCEVIAQALTVEKDKSNPYLHAQIFCGCCFIAALILISILREYSIRMKLTERQAMTN----------EKLKEWKASEYDTDSADEDWGKLKER---------------------------KTKYDLLLGPGIKKYFLRMVYPMKV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :. . . : . . .. . : :* . . ", "identical_positions": 1, "similar_positions": 16, "identity": "0.07%" }, { "cls_id": "homologset.agr.SGD:S000005070", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JUU7-1", "uniprot_id": "A0A0G2JUU7_RAT", "id": "A0A0G2JUU7-1", "name": "", "aln": "MATPDQKSPNVLLQNLCCRILGRSEADVAQQFQFAVRVIGSNFAPTVERDEFL-VAEKIKKELIRQRREADAALFSELHRKLHSQGVLKNKWSILYLLLNLSEDPRKQASKVTSYASLFAQALPRDAHSTPYYCARPQTLPLNYQDRSTQS---SGSLGSSGISSIGMCGLSGPTPV-QPFLPGQSHQAPGVGDGLRQQLGPRLAWTLTGNQPS-QTPTSKAFPNALSRNLTRSRREGDPGGTSEVTEAALVRDILYVFQGIDGKNIKMSSTENCYKVEAKAN--LSKSLRDTAVRLAELGWLHNKIRKYADQRSLDRSFGLVGQSFCAALHQELKEYYRLLSVLHSQLQLEDDQGVN-----------VGLESSLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMKSLVQHILSLVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVK---TDRLWHDKYTLRKSMIPSFITMDQSRKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPRDAADLFTDLENAFQGKIDAAYFETSKYLLDVLNRKYSLLEHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGILETAVRATNAQFDS-----PEILKRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTREC---MSHYLRVFNFLWRAKRMEYIL-TDIRKG-----HMCNAKLLRNMP-EFSGVLHQCHILASEMVHFIHQMQYYITFEVLECSWDELWNRVQQAQDLDHIIAAHEAFLDTITSRCLLDSNSRVLLNQLRAVFDQIIELQNAQDTMYRAALEELQRRLQFEEKKKQRETEGQWGVTAAEEEEENKRIREFQDSIPKMCSQLRILTHFYQGVVQQFLVLLTTSSDESLQFLSFRLDFNEHYKAREPRLRVSLGSRGRRSSHT----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58854-1", "uniprot_id": "GCP3_MOUSE", "id": "P58854-1", "name": "Gamma-tubulin complex component 3", "aln": "MATPDQKSPNVLLQNLCCRILGRSEADVAQQFQFAVRVIGSNFAPTVERDEFL-VAEKIKKELIRQRREADAALFSELHRKLHSQGVLKNKWSILYLLLNLSEDPRKQASKVTSYASLFAQALPRDAHSTPYYYARPQTLPLNYQDRSTQAQ-SSGSLGSSGISSIGMCGLSGPTPV-QPFLPGQSHQAPGVGDGLRQQLGPRLAWTLTGNQPSSQTPTSKGFPNALSRNLTRSRREGDPGGTLEVTEAALVRDILYVFQGIDGKNIKMSSTENCYKVEAKAN--LNKSLRDTAVRLAELGWLHNKIRKYADQRSLDRSFGLVGQSFCAALHQELKEYYRLLSVLHSQLQLEDDQGVN-----------LGLESSLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMKSLVQHILSLVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVK---TDRLWHDKYTLRKSMIPSFITMDQSRKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPRDAADLFTDLENAFQGKIDAAYFETSKYLLDVLNKKYSLLEHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGILETAVRATNAQFDS-----PEILKRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTREC---MSHYLRVFNFLWRAKRMEYIL-TDIRKG-----HMCNAKLLRNMP-EFSGVLHQCHILASEMVHFIHQMQYYITFEVLECSWDELWNRVQQAQDLDHIIAAHEAFLNTITSRCLLDSNSRVLLNQLRAVFDQIIELQNAQDVMYRAALEELQRRLQFEEKKKQREIEGQWGVTAAEEEEENKRIREFQDSIPKMCSQLRILTHFYQGVVQQFLVLLTTSSDESLQFLSFRLDFNEHYKAREPRLRVSLGSRGRRSSHT----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96CW5-1", "uniprot_id": "GCP3_HUMAN", "id": "Q96CW5-1", "name": "Gamma-tubulin complex component 3", "aln": "MATPDQKSPNVLLQNLCCRILGRSEADVAQQFQYAVRVIGSNFAPTVERDEFL-VAEKIKKELIRQRREADAALFSELHRKLHSQGVLKNKWSILYLLLSLSEDPRRQPSKVSSYATLFAQALPRDAHSTPYYYARPQTLPLSYQDRSAQSAQSSGSVGSSGISSIGLCALSGPAPAPQSLLPGQSNQAPGVGDCLRQQLGSRLAWTLTANQPSSQATTSKGVPSAVSRNMTRSRREGDTGGTMEITEAALVRDILYVFQGIDGKNIKMNNTENCYKVEGKAN--LSRSLRDTAVRLSELGWLHNKIRRYTDQRSLDRSFGLVGQSFCAALHQELREYYRLLSVLHSQLQLEDDQGVN-----------LGLESSLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMRSLVQHILSLVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVK---TDRLWHDKYTLRKSMIPSFMTMDQSRKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPQDAADLFTDLENAFQGKIDAAYFETSKYLLDVLNKKYSLLDHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGILETAVRATNAQFDS-----PEILRRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTREC---MSHYLRVFNFLWRAKRMEYIL-TDIRKG-----HMCNAKLLRNMP-EFSGVLHQCHILASEMVHFIHQMQYYITFEVLECSWDELWNKVQQAQDLDHIIAAHEVFLDTIISRCLLDSDSRALLNQLRAVFDQIIELQNAQDAIYRAALEELQRRLQFEEKKKQREIEGQWGVTAAEEEEENKRIGEFKESIPKMCSQLRILTHFYQGIVQQFLVLLTTSSDESLRFLSFRLDFNEHYKAREPRLRVSLGTRGRRSSHT----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9XYP8-1", "uniprot_id": "GCP3_DROME", "id": "Q9XYP8-1", "name": "Gamma-tubulin complex component 3", "aln": "----------MSQDRIAGIDVATNSTDISNIINEMIICIKGKQMPEVHEKAMD-HLSKMIAANSRVIRDSNMLTERECVQKIMKLLSARNKKEEGKTVSDHFNELYRKLTLTKCDPHMRHSLMTHLLTMTDNSDAEKAVASEDPRTQCDNLTQILVSRLNSISSSIASLNEMG--------VVNGNGVGAAAVTGAAAVTGAAAVTGAAAVTGAAASHSYDATQSSIGLRKQSLPNYLDATKMLPESRHDIVMSAIYSFTGVQGKYLKKDVVTGRFKLDQQNIKFLTTGQAGMLLRLSELGYYHDRVVKFSDVSTGFNAIGSMGQALISKLKEELANFHGQVAMLHDEMQRFRQASVNGIANKGKKDSGPDAGDEMTLFKLLAWYIKPLHRMQWLTKIADACQVKKGGDLASTVYDFLDNGNDMVNKLVEDLLTAICGPLVRMISKWILEGGISDMHREFFVKSIKDVG---VDRLWHDKFRLRLPMLPKFVPMDMANKILMTGKSINFLREICEEQGMMKERDELMKVMESSASQIFSYT-PDTSWHAAVETCYQQTSKHVLDIMVGPHKLLDHLHGMRRYLLLGQGDFISILIENMKNELERPGLDIYANDLTSMLDSALRCTNAQYDD-----PDILNHLDVIVQRPFNGDIGWNIISLQYIVHGPLAAMLEST----MPTYKVLFKPLWRMKHMEFVLSMKIWKE-----QMGNAKALRTMKSEIGKASHRLNLFTSEIMHFIHQMQYYVLFEVIECNWVELQKKMQKATTLDEILEAHEKFLQTILVGCFVS-NKASVEHSLEVVYENIIELEKWQSSFYKDCFKELNARKELSKIVEKSEKKGVYGLTNKMILQRDQEAKIFAEKMDIACRGLEVIATDYEKAVSTFLMSLNSSDDPNLQLFGTRLDFNEYYKKRDTNLSKPLTFEHMRMSNVFAVNSRFVICTPSTQE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53540-1", "uniprot_id": "SPC98_YEAST", "id": "P53540-1", "name": "Spindle pole body component SPC98", "aln": "-------------------------MELEPTLFGIIEALAPQLLSQSHLQTFVSDVVNLLRSSTKSATQLGPLIDFYKLQSLDSPETTIMWHKIEKFLDALFG-------------------IQNTDDMVKYLSVFQSLLPSNYRAKIVQKS-----------SGLNMENLAN------------HEHLLSPVRAPSIYTEASFENMDRFSERRSMVSSPNRYVPSSTYSSVTLRQLSNPYYVNTIPEEDILKYVSYTLLATTSALFPFDHEQIQIPSK------IPNFESGLLHLIFEAGLLYQSLG-YKVEKFRMLNISPMKKALIIEISEELQNYTAFVNNLVS------------------------SGTVVSLKSLYREIYENIIRLRIYCRFTEHLEELSGDTFLIELNIFKSHGDLTIRKIATNLFNSMISLYYEYLMNWLTKGLLRATYGEFFIAENTDTNGTDDDFIYHIPIEFNQERVPAFIPKELAYKIFMIGKSYIFLEKYCKEVQWTNEFSKKYHVLYQSN----SYRGISTNFFEIINDQYSEIVNHTNQILNQKFHYRDVVFALKNILLMGKSDFMDALIEKANDILATPSDSLPNYKLTRVLQEAVQLSSLRHLMNSPRNSSVINGLDARVLDLGHGSVGWDVFTLDYILYPPLSLVLNVNRPFGRKEYLRIFNFLWRFKKNNYFYQKEMLKSNDIIRSFKKIRGYNPLIRDIINKLSRISILRTQFQQFNSKMESYYLNCIIEENFKEMTRKLQRTENKSQNQFDLIRLNNGTIELNGILTPKAEVLTKSSSSKPQKHAIEKTLNIDELESVHNTFLTNILSHKLFATNTSEISVGDYSGQPYPTSLVLLLNSVYEFVKVYCNLNDIGYEIFIKMNLNDHEASNGLLGKFNTNLKEIVSQYKNFKDRLYIFRADLKNDGDEELFLLSKSLR-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : : : : . . . : :: : : . :.: . . : : . . . . . : : : *.: . . . : . : . :. .. :: * : . . : . . : . : * * :: : : :. : ::: : :** :: : * . ::* * . *:: :.: : .*. : : : . *: :..:. .::. : : .*: .* : : ***: . . * ::* :. :* *:. : : *::: *** **.: *.: .: : .. : .. : :: * : :: ::: . : : .::. **:*:.**: *:: : * *. : .** :*: *:: :. :. ..::. **. : *. **::::*:* : *:: :: * :*: *** *: ::. .: * : : : . : :: : :: ::: :* :*: * ::* .: *: .::*:: .. : : : . : . : ::: . ...: :.. : . . : . .: *: :. * :*.. :: :: . ** . .* .. ", "identical_positions": 68, "similar_positions": 257, "identity": "7.12%" }, { "cls_id": "homologset.agr.SGD:S000005071", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V8E2-1", "uniprot_id": "G3V8E2_RAT", "id": "G3V8E2-1", "name": "Striatin-interacting protein 1", "aln": "MTKKGKTSGGDWQLRLSTHAATLNMAIGEISWRKSRESCLTEAIRELSRGCGAAKMEPAAAGPGPLIVNNKQPQPPPPPPPATAQPPPGAPRAAGGLLPAGKAREFNRNQRKDSEGYSESPDLEFEYADTD---KWAAELAELYSYTEGPEFLMNRKCFEEDFRIHVTD-KKWTELDTNQHRTHAMRLLDGLEVT--------------AREKRLKVARAILYVAQG----------------TFGECSSEAEVQFWMRYNIFLLLEVGTFNALVELLNMEIDNSA-ACSSAVRKPAISLADSTDLRVLLNIMYLIVETVHQDCDGDKAEWRTMRQTFRAELGSPLYNNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRTLLGLPPLPEDSIKVIRN-----MRAASPPASASDLIEQQQ------KRGRR-----------------EHKALIKQDNLDAFN-----ERDPYKADD--SREEEEENDD-DNSLEG----EAFPLERDEVM-----PPPLQHPP-TDRLTCPKGLPWAPKVREK----------DIEMFLESSRSKFIGYTLGSDTDTVVGLPRPIHESIKTLKQHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVN---------------RHKEVIVKAISAVLLLLLKHFKLNHIYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVNELPELTAESLEAG---DNNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNARRYDRTHS-----NPDFLPVDNCLQS---------------------------------------VLG-----------------------QRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C079-1", "uniprot_id": "STRP1_MOUSE", "id": "Q8C079-1", "name": "Striatin-interacting protein 1", "aln": "-------------------------------------------------------MEPAAAGPGPLIVNNKQPQPPPPPPPATAQPPPGAPRAAGGLLPGGKAREFNRNQRKDSEGYSESPDLEFEYADTD---KWAAELAELYSYTEGPEFLMNRKCFEEDFRIHVSD-KKWTELDTNQHRTHAMRLLDGLEVT--------------AREKRLKVARAILYVAQG----------------TFGECSSEAEVQFWMRYNIFLLLEVGTFNALVELLNMEIDNSA-ACSSAVRKPAISLADSTDLRVLLNIMYLIVETVHQDCDGDKAEWRTMRQTFRAELGSPLYNNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRTLLGLPPLPEDSIKVIRN-----MRAASPPASASDLIEQQQ------KRGRR-----------------EHKALIKQDNLDAFN-----ERDPYKADD--SREEEEENDD-DSSLEG----EAFPLERDEVM-----PPPLQHPQ-TDRLTCPKGLPWAPKVREK----------DIEMFLESSRSKFIGYTLGSDTNTVVGLPRPIHESIKTLKQHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVN---------------RHKEVIVKAISAVLLLLLKHFKLNHIYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVNELPELTAESLEAG---DNNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNARRYDRTHS-----NPDFLPVDNCLQS---------------------------------------VLG-----------------------QRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VSL9-1", "uniprot_id": "STRP1_HUMAN", "id": "Q5VSL9-1", "name": "Striatin-interacting protein 1", "aln": "-------------------------------------------------------MEPAVGGPGPLIVNNKQPQPPPPPPPAAAQPPPGAPRAAAGLLPGGKAREFNRNQRKDSEGYSESPDLEFEYADTD---KWAAELSELYSYTEGPEFLMNRKCFEEDFRIHVTD-KKWTELDTNQHRTHAMRLLDGLEVT--------------AREKRLKVARAILYVAQG----------------TFGECSSEAEVQSWMRYNIFLLLEVGTFNALVELLNMEIDNSA-ACSSAVRKPAISLADSTDLRVLLNIMYLIVETVHQECEGDKAEWRTMRQTFRAELGSPLYNNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRSILGLPPLPEDSIKVIRN-----MRAASPPASASDLIEQQQ------KRGRR-----------------EHKALIKQDNLDAFN-----ERDPYKADD--SREEEEENDD-DNSLEG----ETFPLERDEVM-----PPPLQHPQ-TDRLTCPKGLPWAPKVREK----------DIEMFLESSRSKFIGYTLGSDTNTVVGLPRPIHESIKTLKQHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVN---------------RHKEVIVKAISAVLLLLLKHFKLNHVYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVHELPELTAESLEAG---DSNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNARRYDRAHS-----NPDFLPVDNCLQS---------------------------------------VLG-----------------------QRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803T2-1", "uniprot_id": "STRP1_DANRE", "id": "Q803T2-1", "name": "Striatin-interacting protein 1 homolog", "aln": "-----------------------------------------------------------MDGVG-LCANNKQKQ--------------------NQMLPNKMRGEFTRNQRKDSEGLSEAPDLEFEYSDAD---KWTAELSELYSYTEGPEFLLNRKCFEEDFHTHLPD-QKWTELDSVQRRAHAMRLLDGLEVI--------------GRERRLKVARAILYMAQG----------------TFGECSSELEVQHWMRYNVFLLLDVGAFTALVELLNMEIDNSA-ACSSAVRKPAISLADSTDLRVLLNIMYLMVETIQREEPTDSPEWRTIRETFKSELGSPLYNHEPVSVMLFGMVTKFCSGHAPHFPMKKVLLLLWKTILFTLGGFEQLQSCKISRRAALGLPPLPEDSIRVVRS-----MRAASPPASASDLIEQQQ------RRARR-----------------EHKALIKQDNLDTFN-----EKDPYKADD--SHEDEEENDDNDNSLEA----EPFPLERDEVM-----PPPIPHPP-TERMCFPKGLPWAPKVREK----------DIESFLESSRSKFIGYTLGNDTDTVVGLPRPIHESIKTLKQHKYVSIAEVQIAKEEAFQKTPLSGGEEELELCATELLYQGILPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVN---------------RHKEIIVKAISAILLLLLKHFKLNHVYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISALDFPHCVIHELPELTAESLEAG---DNNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKGNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNSRRYDKNQS-----NPEFLPVDNCLQS---------------------------------------VLG-----------------------QRIDLPEDFQMNYDLWLEREVFSKPISWEELLQ--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PI62-1", "uniprot_id": "A0A8M9PI62_DANRE", "id": "A0A8M9PI62-1", "name": "", "aln": "-------------------------------------------------------MQQTDDMEVPLIHDSNSNT--------------------HTCLPQERD---GFHQQKDSEGSMESPNLEFEYGDTD---SFTAELSELYSYTEEPEFSLNRDYFEEDFKNHVKG-RRWMELSVEEQRAYVMRLLDALEVT--------------DRDKRLKVARAILYLAQG----------------VFDECDTETDVLYWSRHNVFLLYDMGIFTALLELLSMEIDNNQ-ACSSAVRKPAISLADSTELRVLLSIMYLMVETIRVEMESDSPERKAAREAFKMELGSPLYNGEPFALLLFTMVTKFCSMNAPHFPMKKVLLLLWKTILFTLGGFEELQEMKVRMRDHLNLPPLPEDSIKVVRN-----MRAASPPASAMELIEQQQQ----QKRGRRSRRSAFVDSLEGDSPYAKKQPLVKQDSLDTYN-----ERDPFKNDD--ARDEEDDPEDVDSGIEG----EVDPLDRDVIIQP-PPPPPPLRPP-TERMSFPKGLPWAPKVREK----------DIEHFLETSRNKFIGFTLGNDIDTLVGLPRPIHESVKTLKLHKYVSIAEVQIKREDELQQCPMTMGEEEVEETPTEILYLGMLPSLSQYVIALLKLLLAAAPTSKAKTDSINILADVLPEEMPITVLQSMKLGIDVN---------------RHKEIIVKAISALLLLLLKHFKLNHIYQFEYVAQHLVFANCIPLILKFFNQNIMSYISAKNSICALDFPHCAVHEMPELTAESLEAG---DSNQFCWRNLFSCINLLRILNKITKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDIDARPWDFQAEECALRESIEKFNTRRYDKNQ------NSEFAPVDNCLQS---------------------------------------VLG-----------------------QRVDLPEDFHYSYEMWLEREVFSQPIQWEGLLQAQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8C9H6-1", "uniprot_id": "STRP2_MOUSE", "id": "Q8C9H6-1", "name": "Striatin-interacting proteins 2", "aln": "------------------------------------------------------MDDPAAPGPAGSPANDNGNGN---------GNGNGNGNGGKGKPAVPKGRETFRNQRRESEGSVDCPTLEFEYGDSD---GHAAELSELYSYTENLEFTTNRKCFEEDFRTQVQDTKEWLELEEDAQKTYVMGLLDRLEVV--------------SREKRLKVARAVLYLAQG----------------TFGECDSEVDVLHWSRYNCFLLYQMGTFSAFLELLHMEIDNSQ-ASSSALRKPAVSIADSTELRVLLSVMYLMVENIRLEREIDPCGWRTARETFRTELSFSTHNEEPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQALKIQKRAELGLPPLAEDSIQVVKS-----MRAASPPSYTLDLGESQLAPPPSKLRGRRG---------------SRRQLLTKQDSLDIYN-----ERDLFKTEEPATEEEEESAADGERTLDG----ELDLLEQDPLVP----PPPSQTPLSTDRVAFPKGLPWAPKVRQK----------DIEHFLEMSRNKFIGFTLGQDTDTLVGLPRPIHESVKTLKQHKYISIADIQIKNEEELEKCPLSLGEEVVPETPSEILYQGMLYSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPVTVLQSMKLGIDVN---------------RHKEIIVKSISALLLLLLKHFKLNHIYQFEYVSQHLVFANCIPLILKFFNQNILSYITAKNSISVLDYPCCTIQDLPELTTESLEAG---DNSQFCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFNSRRYDKPQ------DSEFSPVDNCLQS---------------------------------------VLG-----------------------QRLDLPEDFHYSYELWLEREVFSQPICWEELLQNH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G7M4-1", "uniprot_id": "A0A8I6G7M4_RAT", "id": "A0A8I6G7M4-1", "name": "", "aln": "------------------------------------------------------MDDPAAPGPSGSPANDNGNGN---------GNGNGNGNGGKGKPAVPKGREAFRNQRRESEGSVDCPTLEFEYGDAD---GHAAELSELYSYTESLEFTTNRKCFEEDFKTQVQDTKEWLELEEDAQKTYVMGLLDRLEVV--------------SREQRLKVARAVLYLAQG----------------TFGECDSEVDVLHWSRYNCFLLYRMGTFSAFLELLHMEIDNSQ-ASSSALRKPAVSIADSTELRVLLSVMYLMVENIRLEREIDPCGWRTARETFRTELSFSTHNEEPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQALKIQKRAELGLPPLAEDSIQVVKS-----MRAASPPSYTLDLGESQLAPPPSKLRGRRG---------------SRRQLLTKQDSLDIYN-----ERDLFKTEEPATEEEEESASDGERTLDG----ELDLLEQDPLVP----PPPSQTPLSADRVSFPKGLPWAPKVRQK----------DIEHFLEMSRNKFIGFTLGQDTDTLVGLPRPIHESVKTLKQHKYISIADVQIKNEEELEKCPMSLGEEVIPETPSEILYQGMLYSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPATVLQSMKLGIDVN---------------RHKEIIVKSISALLLLLLKHFKLNHIYQFEYVAQHLVFANCIPLILKFFNQNILSYITAKNSISVLDYPCCTIQDLPELTTESLEAG---DNSQFCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFNSRRYDKPQ------DSEFSPVDNCLQS---------------------------------------VLG-----------------------QRLDLPEDFHYSYELWLEREVFSQPICWEELLQNH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ULQ0-1", "uniprot_id": "STRP2_HUMAN", "id": "Q9ULQ0-1", "name": "Striatin-interacting protein 2", "aln": "------------------------------------------------------MEDPAAPGTGGPPANGNGNG------------------GGKGKQAAPKGREAFRSQRRESEGSVDCPTLEFEYGDAD---GHAAELSELYSYTENLEFTNNRRCFEEDFKTQVQG-KEWLELEEDAQKAYIMGLLDRLEVV--------------SRERRLKVARAVLYLAQG----------------TFGECDSEVDVLHWSRYNCFLLYQMGTFSTFLELLHMEIDNSQ-ACSSALRKPAVSIADSTELRVLLSVMYLMVENIRLERETDPCGWRTARETFRTELSFSMHNEEPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQTLKVQKRAELGLPPLAEDSIQVVKS-----MRAASPPSYTLDLGESQLAPPPSKLRGRRG---------------SRRQLLTKQDSLDIYN-----ERDLFKTEEPATEEEEESAGDGERTLDG----ELDLLEQDPLVP----PPPSQAPLSAERVAFPKGLPWAPKVRQK----------DIEHFLEMSRNKFIGFTLGQDTDTLVGLPRPIHESVKTLKQHKYISIADVQIKNEEELEKCPMSLGEEVVPETPCEILYQGMLYSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPITVLQSMKLGIDVN---------------RHKEIIVKSISTLLLLLLKHFKLNHIYQFEYVSQHLVFANCIPLILKFFNQNILSYITAKNSISVLDYPCCTIQDLPELTTESLEAG---DNSQFCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKLQTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFNSRRYDRPQ------DSEFSPVDNCLQS---------------------------------------VLG-----------------------QRLDLPEDFHYSYELWLEREVFSQPICWEELLQNH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IRD5-1", "uniprot_id": "Q8IRD5_DROME", "id": "Q8IRD5-1", "name": "", "aln": "---------------------------------------------MAWKQKNKLLFDTCKNQLSCGAVNARSSMMQS-------IQSRINVLNTIAASSKRIERASVDTDTHDADANCDGPDLDFVYADVD---GYQNEIAELYSYTEFSEFQMNVKAFEDQMELYDLP-PNWQKQDSASQRGIVMKLVDQLEVS--------------DRSFRMQAARCILYLAQG----------------CWAEVQSDEEQHQITRDNVLVLYQLGVFASFIDLLNMEIESACSPDIVAVKITNVTLVDSTDIRVILSVLYIITETIRDEKEKGSEDYRELADSFVQEINSPLPDGELLAVKLLGMITRFCSGAAPQFPMKKVVLLLWKVSLLGLGGMDVLKNLKNEYRLKVGLEPITEDTLEVTKC-----MRASSPPATATDILENQYP----KRNFKRS--------------LMKQRFLDEPEQIDMEMGGNEGQNNANNGSGNGGNGEEELSQYYRPYDDP----SSSASTTSTANPN-NQPSLTQPPAAVPPVQITARLPWTPKVRQK----------DIDQFLDISRNKFIGYSLIGDHESLAGLPQPIHEGFKTLQRHMYMSLADVQIKKEEDIARNPISTHEDEIKLTPAEVLYQAILPNLPQYMIALLKVLLAASPTSKSKTESINIMADVLPRKMPLTATQSTKLTVDIG---------------RHKEIIVKAVSAIILLYLKHFKINHVYQFEFMSQHLVFANCIPLVLKFFNQTITEYVNTKNSIPLLDFPSCVIGEQPDLSGDSFVYGGEMSDKSYSWRNVFSCINLLRILNKLIKWKHSRVMMLVVFKSAPILKKTLKVRHAMMQLYVLKLLKMQTKYLGRQWRKSNMKTMSAIYAKVRHRLNDDWAFGNDLESRPWDFQAEECTLRACVDRFNLRRYPEATQKCGNNGTAAQNAENAQQSNMMAGNNGCGNNGDANGYGNNGGGGNGGHNQQQQLNDYGVEGGFPSDEILTHSDFAFFGHSGWWDRKVELTDYFKANYAVWLEEEVYNSQTDWDAL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53917-1", "uniprot_id": "FAR11_YEAST", "id": "P53917-1", "name": "Factor arrest protein 11", "aln": "------------------MNASGRSHSKGPIIRSVSLEDLKRNSSFKGNLKYKDEVTSHKEPQVGTLSNEELLKDLDNMLRGKLNMGRNSFHADKRNKSDGNISALTFKARSGLEGDIRTIDIQQDSSDENDNFKFSDDGVNKDRNNEKDNNTDNAVEFQDDAEEAEEENEDESFANVDELDGFDLNKVSDGKHVPINEKGEVDYNMPVDKEFQKSLDQCAASLEERSSAPYALQRAVDWELKMFYSLEDELSEWFCSSDYMHFGQTQTLFKQKITQPQLFFDDENYAASVVECLIEDIPNSLASNLLALSYISMGCFAFTNSKSEHTKIIRRNNLMLVPHIQEIVHAFKKIAISCRDDNRNLKKQTILLFHSSTILYFICSICIEGRGENPEAVNVVIDAFEKTDLLEFLTKYIENWRWNSRLAMRIRNMISLLFKLIVLQFGDSSVYKQTKSSIYNLHG---LTYPSKHPEKLSISPLHYQAFREDITSRFPDYNMPSSGLPKDVDKSESLSQFLEIPRPKSKNPLNMALIVPEKHIATPAPSPPSSPQLMHLGEGPRPRKSFQTNMAYPCLYPSDNEGSEDDTLEDRIDLNIERKPDNDIVIPFSTEEAARILSESLEIKLSTKQLWYERDLFMITERGWKQQLENEPYDYAALNHDANSSKEEKSAICIMQRIDKYYKSCLSSFNSLVFVLLQTMESSLTNNFHRKSEVSDKNLLNMLTPQLEIVRAKELSLKSAAGILHALLKWFKLSHILKFEHLAVVIHDSRYINTCASILSKYSEVYP-ERVFNKYVQTPNSFWKECSLSNESYRESYSVDDSGEVDTEIMPSFAYLLRILRKVTGNKTQR-LKELPLSIGILFKRYYRLFNLDMYHPILKITRELTPFKNKRWKSEHMELISGVYLYEKLELTDNWVTGKDISGELSDACGQEIALRALLQFYNFQHYEISM------------------------------------------------------------------------------------------EDLGYGHRNSSSQDLLNKESEYLNI----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . :. :: .* : : : .* : * *::: . . : :. : :. : . :. : : : . . : . . * : : ::. . . . :. : *. : : . . : : .: : .:: .: . * ..:: :: . : * .* : . :. : ** . : .: * . : .: . : . : : : : . .. * : * . * :. * : : : .. *. .: . :. :* . .*. : *. .:: * * . :: : . : . .: : : :: *: .*:* :. ** . * : :. : ::. * **: :*: : :: ** **:.*: :**.:: : :. * .::.: * : :: * . : . . . .. . . : * ***:*.*: * .* : : :. . ::*: :: : : :**: : * : .::*:. :*: :*.:* : .:.*:*. *:*:... * .:* :** :: :* ::* : : .: ..:: .. : : ", "identical_positions": 68, "similar_positions": 240, "identity": "6.36%" }, { "cls_id": "homologset.agr.SGD:S000005072", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60484-1", "uniprot_id": "PTEN_HUMAN", "id": "P60484-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDK-----KGVTIPSQRRYVYYYSYLLKNHLDYRP--VALLFHKMMFETIPMFSGGTCN-----------------------PQFVVCQLKVKIYSSNSGP-----TRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICS---------------------------IERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O08586-1", "uniprot_id": "PTEN_MOUSE", "id": "O08586-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDK-----KGVTIPSQRRYVYYYSYLLKNHLDYRP--VALLFHKMMFETIPMFSGGTCN-----------------------PQFVVCQLKVKIYSSNSGP-----TRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICS---------------------------IERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHSQITKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O54857-1", "uniprot_id": "PTEN_RAT", "id": "O54857-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDK-----KGVTIPSQRRYVYYYSYLLKNHLDYRP--VALLFHKMMFETIPMFSGGTCN-----------------------PQFVVCQLKVKIYSSNSGP-----TRREDKLMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICS---------------------------IERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHSQITKV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1PHN1-1", "uniprot_id": "A0A8M1PHN1_DANRE", "id": "A0A8M1PHN1-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAMTAKLKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDASKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDENHVAAIHCKAGKGRTGVMICAYLLHRKKFAEAQEALDFYGEVRTRDK-----KGVTIPSQRRYVYYYSYLLKNKLDYKP--VALLFHKMVFQTLPMFSGGTCRDSTVKNRSEVNPQGFKKGSWHWDPQFVVYQLKVKIHTSNPAH-----TRREEKHMIFEFPQPLPVCGDIKVEFFHKQSKMMKKDKMFHFWINTFFIPGPEEAGDKVENGSVVN-DVDSLSCQSQSSPAERDREKERAVAAAALDRERGGERADGEKDYLILTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNSEASTSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEEQHAQITKV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "G5E8H5-1", "uniprot_id": "G5E8H5_MOUSE", "id": "G5E8H5-1", "name": "", "aln": "MYGEKKSHLYLWMEHYGYDMPANIYKMYSQPSRKTDDANKKVSVSASRTIKLNGSTGYDTNEQITLITNGS---SLSYPDEIKSASYADPISTKAYTNDSSVYDPGGASSS-TTLYELNSLSEVSKEIITQGESALLRDKEATSEL-KIPSTLQTQTSMSTNTLSLSDLS-SDYQEEQMNKCKLNQMSKLYDDDERTDIQKSYWNVVKKFVRILVSSVAFRIFGIFLVILDVFLVVVDLNVSEKKIYIPLDYRSISLAIALFFLVDVLLRVSVEGRRRYFSDVLNTLDAVVIGVTVVVAVIYALYDKHFLRDIPRLAVLLRPLRLLILIRILQLAHQKRQLERLTRKLVSGNKRRYKKDGFDLDLTYVTERIIAMSFPSSGRESFYRNPIKEVVRFLDTKHPNHYQVYNLCSERAYDPKHFHYRVRRIMIDDHNVPTLEEMLLFSKEVNNWMAQDPENVVAIHCKGGKGRTGTMVCACLIASEIVLNAKESLYFFGERRTDKSNSSKFQGIETPSQNRYVKYFEKLKINYQLTLPPKKVLVIKRLVVYSIHGVGKGDGSD----------------------LEVQIIMWQETVFSFCNSRNCMIFHDPETDRAIINVFHCPALYDDVKVKFLSPNLPKYYDDCPFFFWFHTSFIKNNR------------------------------------------------------------LYLPRNELDNTHKPKTWKIYGEKFAVEVDFGEN-----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ADC8-1", "uniprot_id": "D4ADC8_RAT", "id": "D4ADC8-1", "name": "", "aln": "MQGVKKSHLYLWMEHYGYDGPASS-RVYSQLSRRRRNANKKVLSSTSKSTKLNGSIGYDGNEETTTFTNGSSIDSMSYQDDMKSSNCMDPTSEKRYGNDSSLYTIDGTLNNGTTLYEMNSLSELSKEVYLN-DSALLRGKEAASELSQVSSTMKTQSSVSTSILSTSDLISEEIQEEQINKCKLNQISKLYDEDEHVDIRESYWSTVKKFVHFLVSSVAFRIFGILLIFLDVFLVAIDLHATEKNIYIPLEYRAISLAIALFFLVDVLLRVYVEGRQRYFSDVLNTLDAVVIGVTVLVAVIYTLYDKQFLRNIPRLAVLLRPLRLLILVRILQLAHQKRQLEKLTRQLVSGNKRRYKKDGFDLDLTYVTERIIAMSFPSSGRESFYRNPIKEVVRFLDTKHPNHYQVYNLCSERSYDPKRFHYRVRRIMIDDHNVPTLEEMLLFSKEVNDWMAQDPENVVAIHCKGGKGRTGTMVCACLIASEIVLNAKASLYFFGERRTDKSNSSKFQGVETPSQNRYVKYFEKLKTSYQLTLPPKKVLVIKRFTVYSIHGVGKGNGSD----------------------LEIQIMMWQETIFSCFNSKNCMIFHDVETDKVIINVFNCPALYDDVKVKFLCPNLPKYYDDCPFFFWFHTSFIRNNR------------------------------------------------------------LYLPRSELDNTHKQKTWKIYGPKFAVEVYFEEISSTVMY-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56180-1", "uniprot_id": "TPTE_HUMAN", "id": "P56180-1", "name": "Putative tyrosine-protein phosphatase TPTE", "aln": "-----------------------------------------------------------MNESPDPTDLAGVIIELGPNDSPQTSEFKGAT------------------------------------------------EEAPAKESPHTSEFKGAARVSP-----------------ISESVLARLSKFEVED--AENVASYDSKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKLYIPLEYRSISLAIALFFLMDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVKTPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIYSIP----RYVRD----------------------LKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNR------------------------------------------------------------LYLPKNELDNLHKQKARRIYPSDFAVEILFGEKMTSSDVVAGSD------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6XPS3-1", "uniprot_id": "TPTE2_HUMAN", "id": "Q6XPS3-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2", "aln": "-----------------------------------------------------------MNESP------------------QTNEFKGTT------------------------------------------------EEAPAKESPHTSEFKGAALVSP-----------------ISKSMLERLSKFEVED--AENVASYDSKIKKIVHSIVSSFAFGIFGVFLVLLDVTLLLADLIFTDSKLYIPLEYRSISLAIGLFFLMDVLLRVFVEGRQQYFSDLFNILDTAIIVIPLLVDVIYIFFDIKLLRNIPRWTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIR----GDVCD----------------------LKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNR------------------------------------------------------------LCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK-----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53916-1", "uniprot_id": "TEP1_YEAST", "id": "P53916-1", "name": "Probable phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TEP1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MREEGSELEMEKGFLKWKPVNLMKKILSLPMKKTKNDIGLRLDISYILVNLIVCSYPVNTYP------------------KLLYRNSLDDLILFLTVYHGKGNFRIFNFRGEKEDSDYKDNDLIGIAAKFESKD----FEIQELRSTLINDGKIPISPIDLETRTLVEEETNNVICERIGWLDHFPPPFELLEEIVDGIENYLSVSKNRVAVLHCRMGKGRSGMITVAYLMKYLQCPLGEARLIFMQARFKYGMT----NGVTIPSQLRYLRYHEFFITHEKAAQEGISNEAVKFKFKFRLAKMTFLRPSS---------------------LITSESAIVTTKIQHYNDDR-----NALLTRKVVYSDIMAHECGGNMTFIFGR-DYLTLENDCRIEFTLGTSKSKAAS--------------------------------------------------------SIISWTSCASCWLNIYLETLMHIIKDDSSPDYFQVERLKRDEMLGTTISWQELDGFGELSTHGLKLFQALKLEWEII-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * * : * . * * :*.:. . : *.:: * .. :* :. : : : ** * :. : : . :::::: . :.:..:**: *..*:* : * *: .: * : . :*: *** **: *. . .: : : . .::.. * : .: : * . * . : . : . . : ", "identical_positions": 30, "similar_positions": 76, "identity": "3.73%" }, { "cls_id": "homologset.agr.SGD:S000005073", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D7C9-1", "uniprot_id": "NRK2_MOUSE", "id": "Q9D7C9-1", "name": "Nicotinamide riboside kinase 2", "aln": "----------------------------------MK-LIIGIGGVTNGGKTTLTNSLLKALP---------------NCCVIHQDDFFKPQDQIAVGED---GFKQWDVLESLDMETMLSTVQAWVKDPHKF-------------------------------------------------------------------ARAHGVSLQSGA----SDTHVLLLEGFLLYSYRPLVDLYSQRYFLTVPYEECKRRRRSR-TYMVPD-----PPGLFDGHVWPMYQKYRREMEQDGVEVVYLDGMKSPEGLFHQVLEDIQNRLLNTS--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZBU8-1", "uniprot_id": "D3ZBU8_RAT", "id": "D3ZBU8-1", "name": "", "aln": "MKLGLAGRRSSTLQIPSSWAVWPPQDQSTLPVPKMK-LIIGIGGVTNGGKTTLTNGLLKALP---------------NCCVIHQDDFFKPQDQIAVGED---GFKQWDVLESLDMEAMLSTVQAWVKDPHKF-------------------------------------------------------------------ARAHGVSLQPGA----SDTHILLLEGFLLYSYKPLVDLYNQRYFLTVPYEECKRRRRSR-TYMVPD-----PPGLFDGHVWPMYQKYKREMERDRVEVVYLDGTKSREGLVHQVLEDVQNRLLNTS--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NPI5-1", "uniprot_id": "NRK2_HUMAN", "id": "Q9NPI5-1", "name": "Nicotinamide riboside kinase 2", "aln": "----------------------------------MK-LIVGIGGMTNGGKTTLTNSLLRALP---------------NCCVIHQDDFFKPQDQIAVGED---GFKQWDVLESLDMEAMLDTVQAWLSSPQKF-------------------------------------------------------------------ARAHGVSVQPEA----SDTHILLLEGFLLYSYKPLVDLYSRRYFLTVPYEECKWRRSTR-NYTVPD-----PPGLFDGHVWPMYQKYRQEMEANGVEVVYLDGMKSREELFREVLEDIQNSLLNRSQESAPSPARPARTQGPGRGCGHRTARPAASQQDSM---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QSN9-1", "uniprot_id": "F1QSN9_DANRE", "id": "F1QSN9-1", "name": "", "aln": "----------------------------------MK-FIIGIGGVTNGGKTTLTGRLIKNLP---------------NCCVVHQDDFFKPQDQIELGED---GFRQWDVITALDMDAMVNTVKGWMENPVKF-------------------------------------------------------------------ARSHGVSVSTTSDP-DSDIHILIVEGFLLYNYKPLIDVYNKCFYVTIPYEECKRRRSTR-TYTVPD-----PPGLFDGHVWPMYLKHRTEMENSSLDIQYLDGMSSKDELYNQLYEDIQNSLLNIL--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q91W63-1", "uniprot_id": "NRK1_MOUSE", "id": "Q91W63-1", "name": "Nicotinamide riboside kinase 1", "aln": "----------------------------------MKRFVIGIGGVTNGGKTTLAKSLQKHLP---------------NCSVISQDDFFKPESEIDIDEN---GFLQYDVLEALNMEKMMSAVSCWMENP----------------------------------------------------------------------GSSAGPAALESA----QGVPILIIEGFLLFNYKPLDTIWNRSYFLTVPYEECKRRRSTR-VYEPPD-----PPGYFDGHVWPMYLKHRQEMSSITWDIVYLDGTRSEEDLFSQVYEDVKQELEKQNGL------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AY91-1", "uniprot_id": "NRK1_RAT", "id": "Q6AY91-1", "name": "Nicotinamide riboside kinase 1", "aln": "----------------------------------MKTFVIGIGGVTNGGKTTLAKNLQKRLP---------------NCSVISQDDFFKPESEIDIDEN---GFLQYDVLEALNMEKMMSAVSCWMENP----------------------------------------------------------------------GSSAGPAALESA----QGVPILIIEGFLLFNYKPLDTIWNRSYFLTVPYEECKRRRSTR-VYEPPD-----PPGYFDGHVWPMYLKHRQEMNSITWDIVYLDGTRSEEDLFSQVYEDVKQELEKQNGL------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NWW6-1", "uniprot_id": "NRK1_HUMAN", "id": "Q9NWW6-1", "name": "Nicotinamide riboside kinase 1", "aln": "----------------------------------MKTFIIGISGVTNSGKTTLAKNLQKHLP---------------NCSVISQDDFFKPESEIETDKN---GFLQYDVLEALNMEKMMSAISCWMESA----------------------------------------------------------------------RHSVVSTDQESA----EEIPILIIEGFLLFNYKPLDTIWNRSYFLTIPYEECKRRRSTR-VYQPPD-----SPGYFDGHVWPMYLKYRQEMQDITWEVVYLDGTKSEEDLFLQVYEDLIQELAKQKCLQVTA--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZR0-1", "uniprot_id": "Q9VZR0_DROME", "id": "Q9VZR0-1", "name": "", "aln": "---------------------------------MPQWLVIGISGVTCGGKTTLAHSLHDYFKGLRGAPLWNSPYTIGEVRLISQDDYFLPVEDKRHQRNEALNAINFELITSLDMAKMLNDIAHIIKGRHVAPEPQEHLVTYANFEHYAQQFQQQYQYNANYYKQANGGVYQYPPQQHPRHHPHHQQHHHQHHQIQQQQQHIMSINAQIAAQLRDKKVNFLLVEGFMIFNQPELLALCNIKYHFHLPYEKCFERRSKR-TYDPPD-----VTGYFELCVWPHYEKNFSEYR-DCKDITFLNGEIAKEKILAFVLHRIVHYFKERCEVPAPAPVVCPPQQKRFGMLYMGPSNNNVMPSACPMEQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53915-1", "uniprot_id": "NRK1_YEAST", "id": "P53915-1", "name": "Nicotinamide riboside kinase", "aln": "-------------------------------MTSKKVILVALSGCSSSGKTTIAKLTASLFT---------------KATLIHEDDFYKHDNEVPVDAK--YNIQNWDSPEALDFKLFGKELDVIKQTGKIATKLIHN------------------------------------------------NNVDDPFTKFHIDRQVWDELKAKYDSINDDKYEVVIVDGFMIFNNTGISKKFDLKILVRAPYEVLKKRRASRKGYQTLDSFWVDPPYYFDEFVYESYRANHAQLFVNGDVEGLLDPRKSKN--IKEFINDDDTPIAKPLSWVCQEILKLCKD-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::.:.* : .****:: : : :: :**:: .: . . ::: :*:: : . : . . .::::**:::. : . . *** ** .* * * . *: *: * : *: : : . . : : ", "identical_positions": 22, "similar_positions": 57, "identity": "6.06%" }, { "cls_id": "homologset.agr.SGD:S000005074", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGS7-1", "uniprot_id": "CEPT1_MOUSE", "id": "Q8BGS7-1", "name": "Choline/ethanolaminephosphotransferase 1", "aln": "----------------------------------------------------------------MSGHRSTRKRCGDSHPESPVGFGHMSTTGCVLNKLFQLPTPPLSRHQLKRLEEHRYQSAGRS-LLEPLMQGYWEWLVGRVPSWIAPNLITIIGLSINICTTILLVFYCP--------TATEQAPLWAYIACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTCIAVQLG----TNPDWMFFCCFAGTFMFYCAHWQTYVSGTLRFGIID-VTEVQIFIIIMHLLAVIGGPP-FWQSMIPVLN---IQMKLLPALCTVAGTIFSCTNYFRVIFTGGV------GKNGSTIAGTSVLSPFLHIGSVITLAVMIYKKSAVQLFEKHP----CLYILTFGFVSAKITNKLVVAHMTKSEMHLHDTAFIGPALLFLDQYFNSFI-------DEYIVLWIALIFSFFDLIRYCVSVCNQIASHLHIHVFRIKAS------TAHSNHH--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AXM5-1", "uniprot_id": "CEPT1_RAT", "id": "Q6AXM5-1", "name": "Choline/ethanolaminephosphotransferase 1", "aln": "----------------------------------------------------------------MSGHRSTRKRCGDSHPESPVGFGHMSTTGCILNKLFQLPTPPLSRHQLKRLEEHRYQSAGRS-LLEPLMQGYWEWLVGRVPSWIAPNLITIIGLSINICTTILLVFYCP--------TATEQAPLWAYIACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTCIAVQLG----TNPDWMFFCCFAGTFMFYCAHWQTYVSGTLRFGIID-VTEVQIFIIIMHLLAVIGGPP-FWQSMIPVLN---IQMKLFPALCTVAGTIFSCTNYFRVIFTGGV------GKNGSTIAGTSVLSPFLHIGSVITLAVMIYKKSAVQLFEKHP----CLYILTFGFVSAKITNKLVVAHMTKSEMHLHDTAFIGPALLFLDQYFNSFI-------DEYIVLWIALVFSFFDLIRYCVSVCNQIASHLHIHVFRIKTS------TAHSNHH--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6K0-1", "uniprot_id": "CEPT1_HUMAN", "id": "Q9Y6K0-1", "name": "Choline/ethanolaminephosphotransferase 1", "aln": "----------------------------------------------------------------MSGHRSTRKRCGDSHPESPVGFGHMSTTGCVLNKLFQLPTPPLSRHQLKRLEEHRYQSAGRS-LLEPLMQGYWEWLVRRVPSWIAPNLITIIGLSINICTTILLVFYCP--------TATEQAPLWAYIACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTCIAVQLG----TNPDWMFFCCFAGTFMFYCAHWQTYVSGTLRFGIID-VTEVQIFIIIMHLLAVIGGPP-FWQSMIPVLN---IQMKIFPALCTVAGTIFSCTNYFRVIFTGGV------GKNGSTIAGTSVLSPFLHIGSVITLAAMIYKKSAVQLFEKHP----CLYILTFGFVSAKITNKLVVAHMTKSEMHLHDTAFIGPALLFLDQYFNSFI-------DEYIVLWIALVFSFFDLIRYCVSVCNQIASHLHIHVFRIKVS------TAHSNHH--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PRW3-1", "uniprot_id": "A0A8M9PRW3_DANRE", "id": "A0A8M9PRW3-1", "name": "Choline/ethanolaminephosphotransferase 1", "aln": "----------------------------------------------------------------MSGLAVAHGRRGGARERGRGVDSSCWFAPGVLRRLFELPAPVLSRHQLKRLEEHRYSSSGRS-LLEPIMQQYWEWLVNRMPPWIAPNLITIVGLVTNIFTTLVLVYYCP--------TATEQAPLWAYLLCAVGLFVYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTSIAVQLG----THPDWMFFCCFAGMFMFYCAHWQTYVSGTLRFGIFD-VTESQICLALLQMFTAAVGPT-IWNVTIPVIN---IQMKIIPALCTFIGVVFSCTNYFRVIFTGGV------GKNGSTIAGTSVLSPVLHIGSVIILAMMIYKKSAVQLFQKHP----CLYILAFGFVSAKITNKLVVAHMTKSEMHLHDVAFLGPGLLFLDQYFNSFI-------DEYLVLWISLILSLFDLVRYCVSVCNEIASHLHICVFKIKPQ------SAAGIQ---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8C025-1", "uniprot_id": "CHPT1_MOUSE", "id": "Q8C025-1", "name": "Cholinephosphotransferase 1", "aln": "----------------------------------------------------------------MAAGAGARP----------------------APRWVKALGEPLSAAQLRRLEEHRYTAVGES-LFEPPLQLYWTWLLQWIPLWMAPNTITLIGLAINLVTTLVLIFYCP--------TVTEEAPYWTYLLCALGLFIYQSLDAIDGKQARRTNSCSPLGELFDHGCDSLSTVFMAIGASIAVRLG----THPDWLFFCSFVGMFMFYCAHWQTYVSGVLRFGRVD-VTEIQVALVIVFMLSTFGGAT-MWDYTIPILE---IKLKIVPVLGVVGGLIFSCSNYFHVILHGGV------GKNGSTIAGTSVLSPGLHIGLIIILAIMIYKKSATNMFEKHP----CLYTLMFGCVFAKVAQKLVIAHMTKSELYLQDTVFIGPGLLFLDQYFNNFI-------DEYVVLWIAMVISSFDMMIYFTSLCLQISRHLHLNIFKTSCQ------QAPEQVYKHID----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66H21-1", "uniprot_id": "CHPT1_RAT", "id": "Q66H21-1", "name": "Cholinephosphotransferase 1", "aln": "----------------------------------------------------------------MAAGAGARP----------------------APRWVKALGEPLSAAQLRRLEDHRYSAAGES-LFEPPLQLFWTWLLQWIPLWIAPNTITLFGLAINLFTTLVLIFYCP--------TVTEEAPYWTYLLCALGLFIYQSLDAIDGKQARRTNSCSPLGELFDHGCDSLSTVFMAIGASIAVRLG----THPDWLFFCSFVGMFMFYCAHWQTYVSGVLRFGRVD-VTEIQVALVIVFLLSTFGGAM-MWDYTIPILE---IKLKILPVLGVVGGLIFSCSNYFHVILHGGV------GKNGSTIAGTSVLSPGLHIGLIIILAIMIYKKSATNVFEKHP----CLYTLMFGCVFAKVAQKLVIAHMTKSELYLQDTVFIGPGLLFLDQYFNNFI-------DEYVVLWIAMVITSFDMMIYFSSLCLQISRHLHLSIFKTSYQ------QAPEQVHKHID----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WUD6-1", "uniprot_id": "CHPT1_HUMAN", "id": "Q8WUD6-1", "name": "Cholinephosphotransferase 1", "aln": "----------------------------------------------------------------MAAGAGAGS----------------------APRWLRALSEPLSAAQLRRLEEHRYSAAGVS-LLEPPLQLYWTWLLQWIPLWMAPNSITLLGLAVNVVTTLVLISYCP--------TATEEAPYWTYLLCALGLFIYQSLDAIDGKQARRTNSCSPLGELFDHGCDSLSTVFMAVGASIAARLG----TYPDWFFFCSFIGMFVFYCAHWQTYVSGMLRFGKVD-VTEIQIALVIVFVLSAFGGAT-MWDYTIPILE---IKLKILPVLGFLGGVIFSCSNYFHVILHGGV------GKNGSTIAGTSVLSPGLHIGLIIILAIMIYKKSATDVFEKHP----CLYILMFGCVFAKVSQKLVVAHMTKSELYLQDTVFLGPGLLFLDQYFNNFI-------DEYVVLWMAMVISSFDMVIYFSALCLQISRHLHLNIFKTACH------QAPEQVQVLSSKSHQNNMD--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZW02-1", "uniprot_id": "CHPT1_DANRE", "id": "Q7ZW02-1", "name": "Cholinephosphotransferase 1", "aln": "------------------------------------------------------------------------------------------------MPQCECP-EPLSAVQLKRLEEHKYSAAGRS-LFEPPCQIYWNWLVQQIPTWVAPNTLTTIGLVINVITTVILVYYSP--------TATEEVPGWAFFLSALGLFIYQSLDAIDGKQARRTNSSSALGELFDHGCDAVSTVFVAVGTCICCGIG----AYPNWMFFCGFVGMFMFFCAHWQTYVSGTLRFGLVD-VTEVQIAIIIMYLLTAFTGVS-FWEMRVPVLG---VNLQTFPILGIIGGFLYSTYNYFFVIMNGGV------GKNGSTVADTSVLTPGLHIGLILTLAFIIFKKSSSHLFEHHP----CLYVLTFGMVIAKISNKLVVAHMTKSELHLQDTAFIGPGLLFLNQYFNSYI-------DEHIVLWIAMVLSLVDLVRYCTAVCLQIASHLRIRVFSISPQ------GHAHKD---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K7Y4-1", "uniprot_id": "A0A0B4K7Y4_DROME", "id": "A0A0B4K7Y4-1", "name": "diacylglycerol cholinephosphotransferase", "aln": "-----------------------------------------------------------------------------------------------MALLAYRDKHILSAQQLRKLSEHKYSCFSVS-LLDPLLQPWWNWLVAQTPLWLAPNLITIVGLILNVVTTLILICYSP--------NGVEAPPRWTCLLCALGLFIYQSLDSIDGKQARRTNTSSPLGELFDHGCDSISTVFVALSACISCQLG----HYPNWLFFQCFCAIALFYCAHWQTYVSGTMRFGRID-VTEAQFSIIAIHLVSAALGPE-IWLTKLPHFN---CESRFLPIYVACGVDLILALRYTKCILTEGC------GKNGSSVAGTSVLSPSIPLTLVVLPALMIAQKSPQNLFTEHA----SVYIMAFGMVAAKVTNKLVIAHMTKAEMEYLDWSLLGPSLLFLNQYFNCIV-------PEIWLLWFTLIWGTQDLLRYCAQVCLEICQHLRIDLFRIPYT------PKGATPHPATASVSSQSNFGSSADKNGGSAHRKSKSKPH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B4F7D7-1", "uniprot_id": "B4F7D7_RAT", "id": "B4F7D7-1", "name": "Ethanolaminephosphotransferase 1", "aln": "MKRRRQWGGGTWRWLSCSDWVKAVLGADRVRGGVPTRGSLEGCACALGGLRVRGGRSAPLPSLPAQAFLTLHIAVRCSCFLTLSSSVAAAAEWAFSFRVIMAGYEYVSPEQLAGFDKYKYSALDTNPLSLYVMHPFWNTIVKVFPTWLAPNLITFSGFMLLVFNFLLLTYFDPDFYASA--PGHKHVPDWVWIVVGILNFVAYTLDGVDGKQARRTNSSTPLGELFDHGLDSWACVYFVVTVYSIFGRG-PTGVSVFVLYLLLWVVLFSFILSHWEKYNTGVL-FLPWG-YDISQVTISFVYIVTAVVGVE-AWYEPFLFN---FLYRDLFTAMIIGCALCVTLPMSLLNFYRSYK------SNSLKHNSIYEAMVPFFSPCLLFTLSTVWILRSPSDILEMHP----RIFYFMVGTAFANITCQLIVCQMSSTRCPTLNWLLLPLFLVVATVIVGTTTS-----RLESVLLYTLTAAFTLAHIHYGVQVVKQLSRHFQIYPFSLRK-------PNSD-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TA1-1", "uniprot_id": "EPT1_MOUSE", "id": "Q80TA1-1", "name": "Ethanolaminephosphotransferase 1", "aln": "----------------------------------------------------------------------------------------------------MAGYEYVSPEQLSGFDKYKYSALDTNPLSLYIMHPFWNTIVKVFPTWLAPNLITFSGFMLLVFNFLLLTYFDPDFYASA--PGHKHVPDWVWIVVGILNFAAYTLDGVDGKQARRTNSSTPLGELFDHGLDSWSCVYFVVTVYSIFGRG-PTGVSVFVLYLLLWVVLFSFILSHWEKYNTGVL-FLPWG-YDISQVTISFVYIVTAVVGVE-AWYEPFLFN---FLYRDLFTAMIIGCALCVTLPMSLLNFFRSYK------SNTLKHKSVYEAMVPFFSPCLLFTLCTVWILWSPSDILEIHP----RIFYFMVGTAFANITCQLIVCQMSSTRCPTLNWLLLPLLLVVAAVIVGAATS-----RLESALLYTLTAAFTLAHIHYGVQVVKQLSRHFQIYPFSLRK-------PNSDULGMEEQNIGL------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0D9-1", "uniprot_id": "EPT1_HUMAN", "id": "Q9C0D9-1", "name": "Ethanolaminephosphotransferase 1", "aln": "----------------------------------------------------------------------------------------------------MAGYEYVSPEQLAGFDKYKYSAVDTNPLSLYVMHPFWNTIVKVFPTWLAPNLITFSGFLLVVFNFLLMAYFDPDFYASA--PGHKHVPDWVWIVVGILNFVAYTLDGVDGKQARRTNSSTPLGELFDHGLDSWSCVYFVVTVYSIFGRG-STGVSVFVLYLLLWVVLFSFILSHWEKYNTGIL-FLPWG-YDISQVTISFVYIVTAVVGVE-AWYEPFLFN---FLYRDLFTAMIIGCALCVTLPMSLLNFFRSYK------NNTLKLNSVYEAMVPLFSPCLLFILSTAWILWSPSDILELHP----RVFYFMVGTAFANSTCQLIVCQMSSTRCPTLNWLLVPLFLVVLVVNLGVAS------YVESILLYTLTTAFTLAHIHYGVRVVKQLSSHFQIYPFSLRK-------PNSDULGMEEKNIGL------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PAB3-1", "uniprot_id": "A0A8M1PAB3_DANRE", "id": "A0A8M1PAB3-1", "name": "Ethanolaminephosphotransferase 1", "aln": "----------------------------------------------------------------------------------------------------MALYHYVTQEQLSGFDKYKYSAVDSNPLSIYVMHPFWNSVVKVLPTWLAPNLITFTGFMFLVLTFTMLSFFDFDFYASG--EGHTHVPSWVWIAAGLFNFLAYTLDGVDGKQARRTNSSTPLGELFDHGLDSWACVFFVATVYSVFGRG-ETGVSVVTLYYLLWVVLFSFILSHWEKYNTGIL-FLPWG-YDISQVTISIVYIITAVVGVE-TWYKPVFLN---IHYRDLFTVMIIGCLFVVTLPMSLYNVFKAYR------NNTLKHSSLYEALLPFFSPVLLFVLSTLWISFSPTNIVQKQP----RIFYLMVGTAFSNVTCKLIVCQMSNTRCKPLSLLLLPMSIVVLLVISGTVQ------GGESLVLFIWTAVVLLTHIHYGVSVVKQLSDHFNIFAFSLKK-------PNSD--UQDEEKIGLKAAEV-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIU4-1", "uniprot_id": "Q9VIU4_DROME", "id": "Q9VIU4-1", "name": "Ethanolaminephosphotransferase 1", "aln": "---------------------------------------------------------------------------------------------MRQLFRRLMNHQYLTQDQINGFDNYKYSAIDTSPLSQYVMHPFWDWLVKFFPRWFAPNLMTFLGFLFSAMNLVLLSYYDWNFDASSGEEGTTPIPSWVWLCTAINIFLAYTLDGIDGKQARRIGLSGPLGELFDHGLDSYTAMLIPTCLYSIFGRSRVYSVRPMRMYYVCLTVYFNFFISHWEKYNTGIL-YLPWG-YDLSMWGSTAMYLVTWWMGFE-RWKFELPLGSYGTLPLGNVMEAVLHVSAMANLPLVIINVYNSYA------HRTGRLLSFWEAVRPMWPFITYFVILLAWPYVSPNDIMEKDP----RAIFMLSGTIFSNVSCRLIVSQMSVTRCEAWHWQTP---MFILSFLTSLWIP-----LLERPLLYLLLIVTTLSHWQYGASVVNQMCEHFNRVCFTVHKRVPQEELPKKKTLLAEEISQADKPQAEEPLKKDI------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17898-1", "uniprot_id": "CPT1_YEAST", "id": "P17898-1", "name": "Cholinephosphotransferase 1", "aln": "------------------------------------------------------------------------------------------------------MGFFIPQSSLGNLKLYKYQSDDRSFLSNHVLRPFWRKFATIFPLWMAPNLVTLLGFCFIIFNVLTTLYYDP--------YFDQESPRWTYFSYAIGLFLYQTFDACDGMHARRTGQQGPLGELFDHCIDSINTTLSMIPVCSMTGMG-----YTYMTIFSQFAILCSFYLSTWEEYHTHKLYLAEFCGPVEGIIVLCISFIAVGIYGPQTIWHTKVAQFS---WQDFVFDVETVHLMYAFCTGALIFNIVTAHTNVVRYYESQSTKSATPSKTAENISKAVNGLLPFFAYFSSIFTLVLIQPSFISLALILSIGFSVAFVVGRMIIAHLTMQPFPMVNFPFLIPTIQLVLYAFMVYVLDYQKGSIVSALVWMGLGLTLAIHGMFINDIIYDITTFLDIYALSIKHP--------KEI----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .: :. ::* . . . * : :* . * *.*** :* *: . : * *. : . * ::*. ** :*** . .******* *: . * : *: * : : : * * . . . : . * :. .. : * : ::::.::: : . ::: : : :: .: : ", "identical_positions": 34, "similar_positions": 66, "identity": "6.15%" }, { "cls_id": "homologset.agr.SGD:S000005075", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q75Q41-1", "uniprot_id": "TOM22_RAT", "id": "Q75Q41-1", "name": "Mitochondrial import receptor subunit TOM22 homolog", "aln": "-----------MAAAVAAAGAGEPLSPEELVPKAEAEKAEEDLEEDDD------DELDE--TLSERLWGLTEMFPERVRSAAGATFDLSLFVAQKMYRFSRAALWIGTTSFMILVLPVVFETEKLQMEQQQQLQQRQILLGPNTGLSGGMPGALPPLPGKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CPQ3-1", "uniprot_id": "TOM22_MOUSE", "id": "Q9CPQ3-1", "name": "Mitochondrial import receptor subunit TOM22 homolog", "aln": "-----------MAAAVAAAGAGEPLSPEELLPKAEAEKAEEELEEDDD------DELDE--TLSERLWGLTEMFPERVRSAAGATFDLSLFVAQKMYRFSRAALWIGTTSFMILVLPVVFETEKLQMEQQQQLQQRQILLGPNTGLSGGMPGALPPLPGKM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NS69-1", "uniprot_id": "TOM22_HUMAN", "id": "Q9NS69-1", "name": "Mitochondrial import receptor subunit TOM22 homolog", "aln": "-----------MAAAVAAAGAGEPQSPDELLPKGDAEKPEEELEEDDD------EELDE--TLSERLWGLTEMFPERVRSAAGATFDLSLFVAQKMYRFSRAALWIGTTSFMILVLPVVFETEKLQMEQQQQLQQRQILLGPNTGLSGGMPGALPSLPGKI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZL1-1", "uniprot_id": "Q9VZL1_DROME", "id": "Q9VZL1-1", "name": "Mitochondrial import receptor subunit TOM22 homolog", "aln": "MDSDPEIEFIEKDSGMSSLGGSKDETPE---RRAVAATSNDPQRENYD------DEPDE--TASERFWGLTEMFPEPVRNAVGAVSSATVKSVKGFYSFSCNASWIFFTSAVILFAPVIFETERAQMEELHKSQQKQVLLGPGSAMGPGGP--SPSLPLIR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P49334-1", "uniprot_id": "TOM22_YEAST", "id": "P49334-1", "name": "Mitochondrial import receptor subunit TOM22", "aln": "-----MVELTEIKDDVVQLDEPQFSRNQAIVEEKASATNNDVVDDEDDSDSDFEDEFDENETLLDRIVALKDIVPPGKRQTISNFFGFTSSFVRNAFTKSGNLAWTLTTTALLLGVPLSLS-ILAEQQLIEMEKTFDLQSDANNILAQGEKDAAATAN---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : . : . :: :: * :* ** * :*: .*.::.* *.: . . : .: : * * *: ::* *: :. : : . : :: .... :. * .. ", "identical_positions": 15, "similar_positions": 47, "identity": "9.32%" }, { "cls_id": "homologset.agr.SGD:S000005076", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V752-1", "uniprot_id": "G3V752_RAT", "id": "G3V752-1", "name": "RNA cytidine acetyltransferase", "aln": "MHRKKVDNRIRILIENGVSERQRSLFVVVGDRGKDQVVILHHMLSKATVKARPSVLWCYKKELG-FSSHRKKRMRQLQKKIKSGTLNIKQDDPFELFVAATNIRYCYYNETHKILGNTFGMCVLQDFEALTPNLLARTVETVEGGGLVVILLRTMNSLKQLYTMTMDVHSRYRTEAHQDVVGRFNERFILSLASCKKCLVIDDQLNILPISSHVASIEALPPQAPDENLSPAALELQELKESLQDTQPVGVLVDCCKTLDQAKAVLKFIEGISEKTLRSTVALTAARGRGKSAALGLAIAGAVAFGYSNIFVTSPSPDNLHTLFEFVFKGFDALQYQEHLDYEIVQSLNPEFNKAVIRVNVFREHRQTIQYIHPADAVKLGQAELVVIDEAAAIPLPLVKSLLGPYLVFMASTINGYEGTGRSLSLKLIQQLRQQSAQS------QVSTTAENKTTTTARLASARTLHEVSLQESIRYAPGDAVEKWLNDLLCLDCLNITR---IVSGCPLPEACELYYVNRDTLFCYHKASEVFLQRLMALYVASHYKNSPNDLQMLSDAPAHHLFCLLPPVPPTQN-ALPEVLAVVQVCLEGELSRQSILNSLSRGKKASGDLLPWTVSEQFQDPDFGGLSGGRVVRIAVHPDYQGMGYGSRALQLLQMYYEGRFPCLEEK---VLETPQEIHTVSSEAVS---LLEEVITPR--KDLPPLLLKLNERPAERLDYLGVSYGLTPRLLKFWKRAGFVPVYLRQTPNDLTGEHSCIMLKTLADEDEAERGAWLAAFWTDFRRRFLALLSYQFSTFSPALSLNIIQNRNIAKSAPP-------VLGREHLEALFLPYDLKRLEMYSRNMVDYHLIMDLIPAISRLYFLNQLGD-LALSAAQSALLLGMGLQHKSVDQLEKEIELPSGQLMGLFNRIIRKVVKLFNDVQEKAIEEQMVAVKDVVMEPT-------------IKTLSDDLDEA-AKEFQEKHKKDVGKLKDMDLSQYIIRGDDEEWN---EVLSKAGQN--ASIVSLKSDKKRK---LETKQEP-KQSKKLKKSGN-NRKDTKLKRKK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K224-1", "uniprot_id": "NAT10_MOUSE", "id": "Q8K224-1", "name": "RNA cytidine acetyltransferase", "aln": "MNRKKVDNRIRILIENGVAERQRSLFVVVGDRGKDQVVILHHMLSKATVKARPSVLWCYKKELG-FSSHRKKRMRQLQKKIKSGTLNLKQDDPFELFVAATNIRYCYYNETHKILGNTFGMCVLQDFEALTPNLLARTVETVEGGGLVVILLRTMNSLKQLYTMTMDVHSRYRTEAHQDVVGRFNERFILSLASCKKCLVIDDQLDILPISSHVASIEALPPQAPDENLSPAALELLELKESLQDTQPVGVLVDCCKTLDQAKAVLKFIEGISEKTLRSTVALTAARGRGKSAALGLAIAGAVAFGYSNIFVTSPSPDNLHTLFEFVFKGFDALQYQEHLDYEIVQSLNPEFNKAVIRVNVFREHRQTIQYIHPADAVKLGQAELVVIDEAAAIPLPLVKSLLGPYLVFMASTINGYEGTGRSLSLKLIQQLRQQSAQS------QVSTTAENKTTTTARLASARTLHEVSLQESIRYAPGDAVEKWLNDLLCLDCLNITR---IVSGCPLPEACELYYVNRDTLFCYHKASEVFLQRLMALYVASHYKNSPNDLQMLSDAPAHHLFCLLPPVPPTQN-ALPEVLAVVQVCLEGEISRQSILNSLSRGKKASGDLIPWTVSEQFQDPDFGGLSGGRVVRIAVHPDYQGMGYGSRALQLLQMYYEGKFPCLEEK---VLETPQEIRTVSSEAVS---LLEEVITPR--KDLPPLLLKLNERPAERLDYLGVSYGLTPRLLKFWKRAGFVPVYLRQTPNDLTGEHSCIMLKTLADEDEAEQGAWLAAFWKDFRRRFLALLSYQFSTFSPALSLNIIQNRNVAKSALP-------ALGREHLEALFLPYDLKRLEMYSRNMVDYHLIMDLIPAISRLYFLNQLGD-LSLSAAQSALLLGIGLQHKSVDQLEKEIELPSGQLMGLFNRIIRKVVKLFNDVQEKAIEEQMVAVKDVVMEPT-------------MKTLSDDLDEA-AKEFQEKHKKEVGKLKDMDLSQYVIRGDDEEWN---EVLSKAGQN--ASIVSLKSDKKRK---LETKQEP-KQSKKLKKRDN-NRKDMKLKRKK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0A0-1", "uniprot_id": "NAT10_HUMAN", "id": "Q9H0A0-1", "name": "RNA cytidine acetyltransferase", "aln": "MHRKKVDNRIRILIENGVAERQRSLFVVVGDRGKDQVVILHHMLSKATVKARPSVLWCYKKELG-FSSHRKKRMRQLQKKIKNGTLNIKQDDPFELFIAATNIRYCYYNETHKILGNTFGMCVLQDFEALTPNLLARTVETVEGGGLVVILLRTMNSLKQLYTVTMDVHSRYRTEAHQDVVGRFNERFILSLASCKKCLVIDDQLNILPISSHVATMEALPPQTPDESLGPSDLELRELKESLQDTQPVGVLVDCCKTLDQAKAVLKFIEGISEKTLRSTVALTAARGRGKSAALGLAIAGAVAFGYSNIFVTSPSPDNLHTLFEFVFKGFDALQYQEHLDYEIIQSLNPEFNKAVIRVNVFREHRQTIQYIHPADAVKLGQAELVVIDEAAAIPLPLVKSLLGPYLVFMASTINGYEGTGRSLSLKLIQQLRQQSAQS------QVSTTAENKTTTTARLASARTLYEVSLQESIRYAPGDAVEKWLNDLLCLDCLNITR---IVSGCPLPEACELYYVNRDTLFCYHKASEVFLQRLMALYVASHYKNSPNDLQMLSDAPAHHLFCLLPPVPPTQN-ALPEVLAVIQVCLEGEISRQSILNSLSRGKKASGDLIPWTVSEQFQDPDFGGLSGGRVVRIAVHPDYQGMGYGSRALQLLQMYYEGRFPCLEEK---VLETPQEIHTVSSEAVS---LLEEVITPR--KDLPPLLLKLNERPAERLDYLGVSYGLTPRLLKFWKRAGFVPVYLRQTPNDLTGEHSCIMLKTLTDEDEADQGGWLAAFWKDFRRRFLALLSYQFSTFSPSLALNIIQNRNMGKPAQP-------ALSREELEALFLPYDLKRLEMYSRNMVDYHLIMDMIPAISRIYFLNQLGD-LALSAAQSALLLGIGLQHKSVDQLEKEIELPSGQLMGLFNRIIRKVVKLFNEVQEKAIEEQMVAAKDVVMEPT-------------MKTLSDDLDEA-AKEFQEKHKKEVGKLKSMDLSEYIIRGDDEEWN---EVLNKAGPN--ASIISLKSDKKRK---LEAKQEP-KQSKKLKNRETKNKKDMKLKRKK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53914-1", "uniprot_id": "NAT10_YEAST", "id": "P53914-1", "name": "RNA cytidine acetyltransferase", "aln": "MAKKAIDSRIPSLIRNGVQTKQRSIFVIVGDRARNQLPNLHYLMMSADLKMNKSVLWAYKKKLLGFTSHRKKRENKIKKEIKRGTREVNEMDPFESFISNQNIRYVYYKESEKILGNTYGMCILQDFEALTPNLLARTIETVEGGGIVVILLKSMSSLKQLYTMTMDVHARYRTEAHGDVVARFNERFILSLGSNPNCLVVDDELNVLPLSG-AKNVKPLPPKEDDE-LPPKQLELQELKESLEDVQPAGSLVSLSKTVNQAHAILSFIDAISEKTLNFTVALTAGRGRGKSAALGISIAAAVSHGYSNIFVTSPSPENLKTLFEFIFKGFDALGYQEHIDYDIIQSTNPDFNKAIVRVDIKRDHRQTIQYIVPQDHQVLGQAELVVIDEAAAIPLPIVKNLLGPYLVFMASTINGYEGTGRSLSLKLIQQLRNQNNTSGRESTQTAVVSRDNKEKDSHLHSQSRQLREISLDEPIRYAPGDPIEKWLNKLLCLDVTLIKNPRFATRGTPHPSQCNLFVVNRDTLFSYHPVSENFLEKMMALYVSSHYKNSPNDLQLMSDAPAHKLFVLLPPIDPKDGGRIPDPLCVIQIALEGEISKESVRNSLSRGQRAGGDLIPWLISQQFQDEEFASLSGARIVRIATNPEYASMGYGSRAIELLRDYFEGKFTDMSED---VRPKDYSIKRVSDKELAKTNLLKDDVKLRDAKTLPPLLLKLSEQPPHYLHYLGVSYGLTQSLHKFWKNNSFVPVYLRQTANDLTGEHTCVMLNVLEGRE----SNWLVEFAKDFRKRFLSLLSYDFHKFTAVQALSVIESSKKAQDLSDDEKHDNKELTRTHLDDIFSPFDLKRLDSYSNNLLDYHVIGDMIPMLALLYFGDKMGDSVKLSSVQSAILLAIGLQRKNIDTIAKELNLPSNQTIAMFAKIMRKMSQYFRQLLSQSIEETLPNIKDDAIAEMDGEEIKNYNAAEALDQMEEDLEEAGSEAVQAMREKQKELINSLNLDKYAINDNSEEWAESQKSLEIAAKA--KGVVSLKTGKKRT---TEKAEDIYRQEMKAMKKPRKSKKAAN-------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W3C1-1", "uniprot_id": "NAT10_DROME", "id": "Q9W3C1-1", "name": "RNA cytidine acetyltransferase", "aln": "MVKKKIDNRIRVMIENGVKLGHRTMFIVIGDKARDQVPILYDILTKSTVKARPTVLWCYKNKDEAISNHGKKR----AKKIAVGKVDVNEADLFDSFRVATTIHGRYYSETHAVLGRTYGVCVLQDFEALTPNLLARTVETVEGGGLIILLLKTLQSLKQLYTMSMDVHKRFRTEAHQTVTCRFNERLILSLADCKRCLVVNDDLTVLPLSSKTINVEPVNPAGAGR--SPNEASLKELKESLLTVQPAGALVNLCKTYDQANAVAQFIEALVDKQLKPPMSLTAARGRGKSAALGLSIAAAVAFGYVNIYVTSPHPENLITLFEFVLKGFDALEYQEHADYTIIRSTNADYKKAIIRINITRSSRQTIQYIAPSDTHLLNAADLLLIDEAAAIPLPLVKKMIGPYLVFMASTINGYEGTGRSLSLKLISQLQKDNNAR----------------------------PPLKLEESIRYQENDDIEKWLINLLCLDASTVPS---ISSGCPTPDACELYYVDRDALFSYHKAAEAFLHRLVSIYVSSHYKNTPNDLQMMSDAPAHHLFCLLGPVQRMDA--LPEILVVIQVALEGQISAQSISDSLGRGKKAAGDLIPWNVAEQYGDRDFPKLCGVRIVRVATHPNYQRMGYGKRAIQLLKDYYARKHTNLEDGPVASKDAGKGIEEVEEEELS---LLKEQIRPR--SRIPTLLQRLHERVPEHVDYIGTSYGLTTELLKFWKNAGFVPVYLSQKSNELTAEHSCIMLHTPNATP------WLGLYYQDFRRRVLKLMGKTFREFETKLCLALLKNKSVDTEGSALK-----VLDKPMLDVYFLPHDLQRLESYARQQSEFRLIIDLLTDIAQLYFQGRIDG-LQLDLVQQGILLALGVQGKTVDALGLELNMPGNQLLAKFFDAMKRCNQCFRSVLEEHIEGGMLREADLSKGEE---------LQPLTLSLDKELDQT-AQKLSKQQRKELKRLKAEQLDEFQIKGTEEDWS---KALETNGTGGGSGLLSVKSGVKRLDGPIETREDGDLAAPLSKKKKKNNPKQRRSQGKSLI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :* :*.** :*.*** :*::*:::**:.::*: *: :: .: :* . :***.**:: ::.* *** *:* *. :::: * *: * .*: **.*:. :**.*:*:*:***************:*******::::**:::.*******::**** *:***** *. *****:****.. .***::*:* :**:*. . .::.: * .. * .* ****** .**.* **. .** :**:*: .**:.: :* *. .::***.**********::**.**:.** **:**** *:** *****::****** **** ** *::* *.:::**::*::: *. ******* * * *. *:*::**********:**.::**************************.**:::. :.*:*.*** .* :**** .***** : * * *. *:*: *:**:**.** .:* **.:::::**:*****:*****::******:** ** *: : :*: * *:*:.***::* :*: :**.**::*.***:** :::*: * :* *.* *:**:*.:*:* ****.**::**: *: :.. :.: *. *..: :: **:: : * . :*.** :* *: .. :.*:*.***** * ****. .****** *..*:**.**:*:**:. ** : ***:*.* *:. * * . .* :::. . * : *: * *.**:**: *:.: ::::* *::. :: :** .::.. : *. .*..:**.:*:* *.:* : *:::*..* :. * ::: : *..: .: ** : * :..:*::: :: .. :.*: :: :*.:: *.. .*:* : *. . .::*:*:. ** * :: : . * . ", "identical_positions": 408, "similar_positions": 328, "identity": "37.88%" }, { "cls_id": "homologset.agr.SGD:S000005079", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P26883-1", "uniprot_id": "FKB1A_MOUSE", "id": "P26883-1", "name": "Peptidyl-prolyl cis-trans isomerase FKBP1A", "aln": "-----MG-VQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFTLGKQEVIRGWEEGVAQMSVGQRAKLIISSDYAYGATGHPGIIPPHATLVFDVELLKLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62658-1", "uniprot_id": "FKB1A_RAT", "id": "Q62658-1", "name": "Peptidyl-prolyl cis-trans isomerase FKBP1A", "aln": "-----MG-VQVETISSGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFTLGKQEVIRGWEEGVAQMSVGQRAKLIISPDYAYGATGHPGIIPPHATLVFDVELLKLE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62942-1", "uniprot_id": "FKB1A_HUMAN", "id": "P62942-1", "name": "Peptidyl-prolyl cis-trans isomerase FKBP1A", "aln": "-----MG-VQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5VVH2-1", "uniprot_id": "FKB1C_HUMAN", "id": "Q5VVH2-1", "name": "Peptidyl-prolyl cis-trans isomerase FKBP1C", "aln": "-----MG-VHVETISPGDWRTFPKRSQTCVMHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVVQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P68106-1", "uniprot_id": "FKB1B_HUMAN", "id": "P68106-1", "name": "Peptidyl-prolyl cis-trans isomerase FKBP1B", "aln": "-----MG-VEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97534-1", "uniprot_id": "FKB1B_RAT", "id": "P97534-1", "name": "Peptidyl-prolyl cis-trans isomerase FKBP1B", "aln": "-----MG-VEIETISPGDGRTFPKKGQICVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2I2-1", "uniprot_id": "FKB1B_MOUSE", "id": "Q9Z2I2-1", "name": "Peptidyl-prolyl cis-trans isomerase FKBP1B", "aln": "-----MG-VEIETISPGDGRTFPKKGQICVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGTAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLSLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48375-1", "uniprot_id": "FKB12_DROME", "id": "P48375-1", "name": "Peptidyl-prolyl cis-trans isomerase Fkbp12", "aln": "-----MG-VQVVPIAPGDGSTYPKNGQKVTVHYTGTLDDGTKFDSSRDRNKPFKFTIGKGEVIRGWDEGVAQLSVGQRAKLICSPDYAYGSRGHPGVIPPNSTLTFDVELLKVE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20081-1", "uniprot_id": "FKBP_YEAST", "id": "P20081-1", "name": "FK506-binding protein 1", "aln": "MSEVIEGNVKIDRISPGDGATFPKTGDLVTIHYTGTLENGQKFDSSVDRGSPFQCNIGVGQVIKGWDVGIPKLSVGEKARLTIPGPYAYGPRGFPGLIPPNSTLVFDVELLKVN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *.: *:.** *:** .: .:**** *::* ***** **..**: :* :**:*:: * ::*:*::*:* . ***. *.**:***::** ******.::", "identical_positions": 49, "similar_positions": 34, "identity": "42.98%" }, { "cls_id": "homologset.agr.SGD:S000005080", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V751-1", "uniprot_id": "G3V751_RAT", "id": "G3V751-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MGEAEVGGTGAPGDKGPGEAAPSPAEETVVWSPEVEVCLFHAMLGHKPVGVNRHFHMICIRDKFSQN----IGRQVPSKVIWDHLSTMYDMQALHESEILPFPNPERNFVLPDEIIQEVREGKVVIEEEMKEEMKEDVDPHSGADD---------------------------------------------VFSSSGSLGKALEKSSKDKEKN---SSDLGCKEGADKRKRSRVTD--------------KVLTANSNPSSPSAAKRRRT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAT2-1", "uniprot_id": "MRGBP_MOUSE", "id": "Q9DAT2-1", "name": "MRG/MORF4L-binding protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MGEAEVGGTGAPGDKGPGEAAPSPAEETVVWSPEVEVCLFHAMLGHKPVGVNRHFHMICIRDKFSQN----IGRQVPSKVIWDHLSTMYDMQALHESEILPFPNPERNFVLPDEIIQEVREGKVVIEEEMKEEMKEDVDPHSGADD---------------------------------------------VFSSSGSLGKALEKSSKDKEKN---SSDLGCKEGADKRKRSRVTD--------------KVLTANSNPSSPSAAKRRRT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NV56-1", "uniprot_id": "MRGBP_HUMAN", "id": "Q9NV56-1", "name": "MRG/MORF4L-binding protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MGEAEVGGGGAAGDKGPGEAATSPAEETVVWSPEVEVCLFHAMLGHKPVGVNRHFHMICIRDKFSQN----IGRQVPSKVIWDHLSTMYDMQALHESEILPFPNPERNFVLPEEIIQEVREGKVMIEEEMKEEMKEDVDPHNGADD---------------------------------------------VFSSSGSLGKASEKSSKDKEKN---SSDLGCKEGADKRKRSRVTD--------------KVLTANSNPSSPSAAKRRRT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7K003-1", "uniprot_id": "MRGBP_DROME", "id": "Q7K003-1", "name": "MRG/MORF4L-binding protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MMAKDKGLAVAG-----TAAPLPAALDHEWSAEEELQLFHAMEGLRPVGINKHFYMSCIVQRLSKS----LNREMPSELIWRHLGTMYKLKELDDLESLPFPNEEREFSLPEQDYGTLQTKKTVEVHANEEAAEAQSAPPTAETN---------------------------------------------GKAPPATKTPVPTNSTKDGDKKPVAKPQEQLPKRPAKRTRGSMSN--------------ESISPSTTPPPVQSNKRRRI--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53911-1", "uniprot_id": "EAF7_YEAST", "id": "P53911-1", "name": "Chromatin modification-related protein EAF7", "aln": "MVVHWTIVDEIRLLRWASEFKPAGIHKHFHMFCIVERMNSPDKYPVTLLQKETMKLGKVFTAKDIWDKLSQSYNLEKIDEMENTYSLEATTESSRNGNGNGDDAEIHEETLLELNNRIRVRKQDFTLPWEEYGELILENARKSPNSNEEYPRVEDMNEKDSTIPKESPSTDLKNDNNKQEKNATIKVKELPEYHTEENDSPIDVQKEPIKEVQSDEKELQREHMSEEEQKMKSTNKTAAPVRKSQRLKRSKEVKFEDEEKEEIEEDNTKDEEQKEKKEEIQEPKITHNEEVDKEKNENEEGDDEREKSTSYENTNGSESEGVDEGVDEELGYESEREAEGKGKQIESEGGNLKKKTENKKGDDQQDDTKKDSKDKNEPLAKRTRHSSSTGNTSNETSPKRKRRKAGSRKNSPPATRVSSRLRNKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *: :*: . *:.:::. :. . . .: : ..: . : *. : : * : *:: :: : * . : : : . : : .. :.. * ::. . . : **.* : : : ...*.. .* * ", "identical_positions": 14, "similar_positions": 61, "identity": "3.29%" }, { "cls_id": "homologset.agr.SGD:S000005082", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08163-1", "uniprot_id": "CAP1_RAT", "id": "Q08163-1", "name": "Adenylyl cyclase-associated protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADMQNLVERLERAVGRLEAVS---HTSDM------------------HCGYGDSPSK-GAVPY----VQAFDSLLANPVAEYLKMSKEIGGDVQKHAEMVHTGLKLERALLVTASQCQQP--AGNKLSDLLAPISEQIQEVITFREKNRGSKFFNHLSAVSESIQALGWVALAAKPGPFVKEMNDAAMFYTNRVLKEYRDVDKKHVDWVRAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSG------------LPSGPSVGSGPPPPPPGPPPPPVPTSSGSDD-SASRS-----ALFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSPKPATKKEPALLELEGKKWRVENQENVSNLVIDDTELKQVAYIYKCVNTTLQIKGKINSITVDNCKKLGLVFDDVVGIVEIINSRDVKVQVMGKVPTISINKTDGCHAYLSKNSLDCEIVSAKSSEMNVLIPT-EGGDFNEFPVPEQFKTLWNGQKLVTTVTEIAG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40124-1", "uniprot_id": "CAP1_MOUSE", "id": "P40124-1", "name": "Adenylyl cyclase-associated protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADMQNLVERLERAVGRLEAVS---HTSDM------------------HCGYGDSPSK-GAVPY----VQAFDSLLANPVAEYLKMSKEIGGDVQKHAEMVHTGLKLERALLATASQCQQP--AGNKLSDLLAPISEQIQEVITFREKNRGSKFFNHLSAVSESIQALGWVALAAKPGPFVKEMNDAAMFYTNRVLKEYRDVDKKHVDWVRAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSG------------LPSGPSVGSGPPPPPPGPPPPPISTSSGSDD-SASRS-----ALFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSPKPATKKEPALLELEGKKWRVENQENVSNLVIDDTELKQVAYIYKCVNTTLQIKGKINSITVDNCKKLGLVFDDVVGIVEIINSRDVKVQVMGKVPTISINKTDGCHAYLSKNSLDCEIVSAKSSEMNVLIPT-EGGDFNEFPVPEQFKTLWNGQKLVTTVTEIAG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01518-1", "uniprot_id": "CAP1_HUMAN", "id": "Q01518-1", "name": "Adenylyl cyclase-associated protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADMQNLVERLERAVGRLEAVS---HTSDM------------------HRGYADSPSKAGAAPY----VQAFDSLLAGPVAEYLKISKEIGGDVQKHAEMVHTGLKLERALLVTASQCQQP--AENKLSDLLAPISEQIKEVITFREKNRGSKLFNHLSAVSESIQALGWVAMAPKPGPYVKEMNDAAMFYTNRVLKEYKDVDKKHVDWVKAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSG------------LPSGPSAGSCPPPPPPCPPPPPVSTISCSYE-SASRS-----SLFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIYKCVNTTLQIKGKINSITVDNCKKLGLVFDDVVGIVEIINSKDVKVQVMGKVPTISINKTDGCHAYLSKNSLDCEIVSAKSSEMNVLIPT-EGGDFNEFPVPEQFKTLWNGQKLVTTVTEIAG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CYT6-1", "uniprot_id": "CAP2_MOUSE", "id": "Q9CYT6-1", "name": "Adenylyl cyclase-associated protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDMAGLMERLERAVIRLEQLSAGLDGPPR------------------GCGEVNGVN-GGVAPS----VEAFDKLINSMVAEFLKNSRVLAGDVETHAEMVHGAFQAQRAFLLMVSQYQQP--QENEVAVLLKPISEKIQEIQTFRERNRGSNMFNHLSAVSESIAALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLRHVDWVRSYLNIWSELQAYIREHHTTGLTWSKTGPVASTASAF---------SILSSGPGLPPPPPPPPPPGPPPPFENEDKKEEPSPSRS-----ALFAQLNQGEAITKGLRHVTDDKKTYKNPSLRAQG-QIRSPTKTH-TPSPTSPKS--NSPQKHTPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCDKSTLQIKGKVNSITVDNCKKFGLVFDHVVGIVEVINSKDIQIQVMGRVPTISINKTEGCHLYLSEDALDCEIVSAKSSEMNVLVP--QDDDYREFPIPEQFKTIWDGSKLVTEPAEIMA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52481-1", "uniprot_id": "CAP2_RAT", "id": "P52481-1", "name": "Adenylyl cyclase-associated protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADMLGLMQRLEFAVSRLERLSSGLHEPPG------------------GCGEVNSLSRGIVAPS----VEAFDKLINSMVAEFLKNSRVLAGDVETHAEMVHGAFQAQRAFLLMVSQHQQP--QENEVAVLLKPISEKIQEIQTFRERNRGSDMFNHLSAVSESIAALGWIAVSPKPGPYVKEMNDAATFYTNRVLRDYKHSDLRHVDWVRSYLKIWSELQAYIKEHHTTGLTWSKTGPVASTASAF---------SILSSGPGLPPPPPPPPPPGPPPPFENEGGKEEPSPSRS-----ALFAQLNQGEAITKGLRHVTDDKKIYKNPSLRAQG-QIRSPTKTR-TPSPTSSKS--NSPQKHAPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCDKSTLQIKGKVNSITVDNCKKFGLVFDHVVGIVEVINSKDIQIQVMGRVPTISINKTEGCHLYLSKDALDCEIVSAKSSEMNVLVP--QGDDYREFPIPEQFKTIWDGSKLITEPAEIMA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40123-1", "uniprot_id": "CAP2_HUMAN", "id": "P40123-1", "name": "Adenylyl cyclase-associated protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANMQGLVERLERAVSRLESLSAESHRPPG------------------NCGEVNGVI-AGVAPS----VEAFDKLMDSMVAEFLKNSRILAGDVETHAEMVHSAFQAQRAFLLMASQYQQP--HENDVAALLKPISEKIQEIQTFRERNRGSNMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLRHVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASTVSAF---------SVLSSGPGLPPPPPPLPPPGPPPLFENEGKKEESSPSRS-----ALFAQLNQGEAITKGLRHVTDDQKTYKNPSLRAQGGQTQSPTKSH-TPSPTSPKS--YPSQKHAPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCEKSTIQIKGKVNSIIIDNCKKLGLVFDNVVGIVEVINSQDIQIQVMGRVPTISINKTEGCHIYLSEDALDCEIVSAKSSEMNILIP--QDGDYREFPIPEQFKTAWDGSKLITEPAEIMA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IXA9-1", "uniprot_id": "A0A0R4IXA9_DANRE", "id": "A0A0R4IXA9-1", "name": "Adenylyl cyclase-associated protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEALVGRLERAVVRLEAVAVKLQSCPGGL----------------INGDISAVINGGESQS----MEAFDRLLSGSVSEYVQSSAAIGGDVAKHAEMVNNALQVQRTLLKMAMTHQEP--AKTELADLLRPLSDQIQAVQNFREKNRGSSLFNHLSAVSESIPALGWVAVCQKPGPYVKEMNDAAMFYTNRVLKDFKDTDARHVEWVRSYLSIWTDLQTFIREHHCTGLIWSKTGPKAP-----------------PSLLSAPLLPPPPPPPPPMMIDSCSSPADASSVQHA-----ALFAQLNQGEEITKGLKHVCDEQKTHKNPNLRSQSGKTHHD-----SPSKTQSSSSSNPARKHPPVLELEGKKWRVEYQDQCAELLIEDTELRQVVYVFSCSGSTLQVKGKVNSIIVDNCKKLGLVFDNVVGIVEIINSRDIQLQVMGKVPTISINKTEGCHVYLSKDSLDCEIVSAKSSEMNILVPE-GEDDYREFPVPEQFKTVWDGSSLVTEPTKIAG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPX6-1", "uniprot_id": "Q9VPX6_DROME", "id": "Q9VPX6-1", "name": "Adenylyl cyclase-associated protein", "aln": "MFSCCRSNPKAGKKEKEKRNAEEENGGQVTEKEEPQLNGKPGTPKEEPEPVKPEKELLEAHNPEDVPTSTQPNTAQPTQAEAASKSSPANPALAPKEPEPLARSTHSSTSTAPPASMTSGDAEEADEVVVVATVTPTTPPPQPPPTKSCLSRHNSTHQSIKKKVNISNRAEIIEPDPLPLLLLASQNQGSLLDDDEVFSDSLPPPKRESMCAPYIEGDVVSETLFFAHGLPSWFDDERLNDIGCIEPPVTPVGRDELELKRQRLYTELLRAAHAAVEHSVAVRDNEPEAKPSAAVDHLESICERLETLVDRLERTLTAPQPIELPTPTLPPP-PAEEEEALPVFEKAETPPPPPSPPSSNMSVAGFEDIVAGPLSQYLTLSAKIGGDVAQHAELVKSAFGSQLQYVTLATQIAQP--AQPKQAELLKPTSTQISAIQDFREKHRSSPFFNHLSAISESIPALGWVCVEKTPGPYVKEMNDAGQFYTNRVLKEWKEKDVTHVEWARAWVQTLTELQAYIRQYHTTGLVWSGKG-------------------AAPAGGAPPPPPPGGLPPPPPMLDLSALKLDSAGDDRS-----ALFAQINQGADITKGLKKVTGDMQTHKNPSLRTGPAPFKSPAQSG-GSKAVAAPS---AAQAKAPVFERDGKKWIIEYQKNNTGLLVENAEMNNVVYVFKCEGSTLTVKGKVNNIVFDSCKKCSLLFDSVVASVEFVNCQSVQMQVLGSVPTVSIDKTDGCQMYLSKDSLGVEIVNSKSSEMNILLPD-DSGDYTELALPEQYKTTIAGKTLKTVCVDSLG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17555-1", "uniprot_id": "CAP_YEAST", "id": "P17555-1", "name": "Adenylyl cyclase-associated protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPDSKYTMQGYNLVKLLKRLEEATARLEDVTIYQEGYIQNKLEASKNNKPSDSGADANTTNEPSAENAPEVEQDPKCITAFQSYIGENIDPLVELSGKIDTVVLDALQLLKGGFQSQLTFLRAAVRSRKPDYSSQTFADSLRPINENIIKLGQLKESNRQSKYFAYLSALSEGAPLFSWVAVD-TPVSMVTDFKDAAQFWTNRILKEYRESDPNAVEWVKKFLASFDNLKAYIKEYHTTGVSWKKDGMDFADAMAQSTKNTGATSSPSPASATAAPAPPPPPPAPPASVFEISNDTPATSSDANKGGIGAVFAELNQGENITKGLKKVDKSQQTHKNPELRQSSTVSSTGSKSGPPPRPKKPST---LKTKRPPRKELVGNKWFIENYENETESLVIDANKDESIFIGKCSQVLVQIKGKVNAISLSETESCSVVLDSSISGMDVIKSNKFGIQVNHSLPQISIDKSDGGNIYLSKESLNTEIYTSCSTAINVNLPIGEDDDYVEFPIPEQMKHSFADGKFKSAVFEHAG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *** . *** . : .*: : : : * : * :::: .: : : . :* : * * . :* : ::* :* * * :***:**. :.*:.: .* . *.:::**. *:***:*::::. * *:*.: :: :*:::*::.* **: *. * .: ** * * . . ::**::*** **:.*::* . : :*** *: . . : ... * *:** :* .: :: ::: : :: .* : :***:* * ... :. .:::* :. ::.::.... :** :* :**:*::* : ***:::*. ** .: *: :*: :* .*: *:.:*** * . .: : . .", "identical_positions": 93, "similar_positions": 150, "identity": "11.41%" }, { "cls_id": "homologset.agr.SGD:S000005083", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LZ00-1", "uniprot_id": "F1LZ00_RAT", "id": "F1LZ00-1", "name": "THO complex subunit 2", "aln": "---------------------------------------------MASTT-------VVVPAEWIKTWEKSGRGEFLRLCRILSESKS------RDTLACRDFQQALYELSYHVIKGTLKPEQASSVLNDISEFREDIPFILADIFCILDIETNCLEE--KSKRDHFTQLILACLYLVSDTVLKERLDPETLESLGLIKQSQQFNQKSVKIKTKLFYKQQKFNLLREENEGYAKLIVELGQDLSGS---ITSDLILEILKSLIGCFNLDPNRVLDIILEVFECRPEH-HDFFISLLQA----------------YMSMCEPQTLCHILGFKFKFYQEPNGETPSSLYR-AAAVLLQFNLLDLDDLYVHLLPADSCIMNEYKREIVEAKQIVKK------LTMVVLPSEKSDEREKEK--KKDD-KVEKAPDNQ--------------------KLGLLEALLIIGDWQHAQSIMDRMPPYYATSHKVIALAICNLIHITIEPIYRR----------------VGVPKGAKGSPVSALQNKK--APKQAESFEDLRRDVFSMFCY-LGPHLSHDPILFAKVVRIGKS------------FMKEFQSDG-KQENKE-KMETILSCLLSVTDQVLLPSLSLMDCNACMSEELWAMFKTFPYQHRYRLYGQWKNETYNSHPLLVKVKAHTIDRAKYIMKRLTKENVKPSGRQIGKLSHSNPTILFDYILSQIQKYDNLITPVVDSLKYLTALNYDVLAYCIIEALANPEKERMKHDDTTISNWLQSLASFCGAVFRKYP-IDLAGLLQYVANQLKAGKSFDLLILKEVVQKMAGIEVTEEMTMEQLEAMTGGEQLKAEGG--YFGQIRNTKKSSQRLKDALLDHDLALPLCLLMAQQRNGVIFQE-GGEKHLKLVGKLYDQCHDTLVQFGGFLASNLSTDDYIKRVPSIDVLCNEFHTPHDAAFFLSRPMYAHHISSKYDELKKSEKGSKQQ---HKVHKYITSCEMVMAPVHEAVVSLHISKVWEDISPQFYTTFWSLTMYDLAVPHTSYEREVNKLKIQMKAVDDNQEMPLNKKKKEKERCTALQDKLLEEEKKQMEHVQRVLHRLKLEKDNWLLAKS---TKNETITKFLQLCIFPRCIFSAIDSVYCAHFVELVHQQKTPNFSTLLCYDRVFSDIIYMVASFTENEASRYGRFLCCMLETVTRWHSDRSTYEKECGNYPGFLTILRAT-GFDGGNKADQLDYENFRHVVHKWHYKLTKASVHCLETGEYTHIRNILIVLTKILPWYPKVLNLGQALERRVHKICQEEKEKKPDLYALAMVYSGQLKSRKSYMIPENEFHHKDPPPRNAATSVQPNGPCSG-LPSSIGSTSKL-DESSAEEADKSRERSQCAVKAVNKASSVIPKGNL--SNGNSGSNT-KAVKENDKEKGKEKEKEKKEKAPAVTPEARVLGKDSKEKPKEEQPNKDEKIREAKERMPKSDKDKEKLKKEEKAKDEKFRIIVPNVESKSTQEREKEKEPSRERDLAKEMK-SKENVKGGEKAPLSGSLKSPVSRTDIIE-PERE-KRRKVDSHPSPSHASTIK---------------------------DSLVKLKESSAKLYINHIPPPLCKSKEREADKKDLDKSRERSREREKKEEKDRKERKRD-YSNNDREAPLDLIK-RRKDENGILGVSKHKSESPCESLYPNEKDKEKIKSKSSGKEKSD--SFKPEKIDKISSG-KKESGHDKEKIEKKEKWDSSGDKEEKKHHKSSDKHR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q5E2-1", "uniprot_id": "E9Q5E2_MOUSE", "id": "E9Q5E2-1", "name": "THO complex subunit 2", "aln": "-------------------------------------------MAMTSTT-------VVVPAEWIKTWEKSGRGEFLRLCRILSESKS------RDTFAWRDFQQALYELSYHVIKGTLKPEQASNVLNDISEFREDIPFILADIFCILDIETNCLEE--KSKRDHFTQLILACLYLVSDTVLKERLDPETLGSLGLIKQSQQFNQKSVKIKTKLFYKQQKFNLLREENEGYAKLIVELGQDLSGN---ITSDLILEILKSLIGCFNLDPNRVLDIILEVFECRPEH-HDFFISLLEA----------------YMSMCEPHTLCHILGFKFKFYQEPNGETPSSLYR-AAAVLLQFNLIDLDDLYVHLLPADSCIVSEYKREIVEAKQIVKK------LTMVVLPSEKSDEREKEK--KKDD-KVEKAPDNQ--------------------KLGLLEALLIIGDWKHAQSIMDHMPPYYATSHKVIALAICNLIHITIEPIYRR----------------VGVPKGAKGSPVNALQNKK--APKQAESFEDLRRDVFSMFYY-LGPHLSHDPILFAKVVRIGKS------------FMKEFQSDG-KQENKE-KMEAILSCLLSVTDQVLLPSLSLMDCNACMSEELWGMFKTFPYQHRYRLYGQWKNETYNSHPLLVKVKAYTIDRAKYIMKRLTKENVKPSGRQIGKLSHSNPTILFDYILSQIQKYDNLITPVVDSLKYLTALNYDVLAYCIIEALANPEKERMKHDDTTISNWLQSLASFCGAVFRKYP-IDLAGLLQYVANQLKAGKSFDLLILKEVVQKMAGIEVTEEMTMEQLEAMTGGEQLKAEGG--YFGQIRNTKKSSQRLKDALLDHDLALPLCLLMAQQRNGVIFQE-GGEKHLKLVGKLYDQCHDTLVQFGGFLASNLSTDDYIKRVPSIDVLCNEFHTPHDAAFFLSRPMYAHHISSKYDELKKSEKGSKQQ---HKVHKYIMSCEMVMAPVHEAVVSLHISKVWDDISPQFYTTFWSLTMYDLAVPHTSYEREVNKLKIQMKAVDDSQEMPLNKKKKEKERCTALQDKLLEEEKKQTEHVQRVLHRLKLEKDNWLLAKS---TKNETITKFLQLCIFPRCIFSAIDSVYCAHFVELVHQQKTPNFSTLLCYDRVFSDIIYMVASFTENEASRYGRFLCCMLETVTRWHSDRSTYEKECGNYPGFLTILRAT-GFDGGNKADQLDYENFRHVVHKWHYKLTKASVHCLETGEYTHIRNILIVLTKILPWYPKVLNLGQALERRVHKICQEEKEKKPDLYALAMVYSGQLKSRKSYMIPENEFHHKDPPPRNTATNLQPSGPCSG-LPSSIGSMCKL-DESSAEEADKSRERAQCAVKAANKASSVTPKGNL--SNGNSGSNS-KAVKENDKEKGKEKEKEKKEKTPAVTPEARVLGKDSKEKPKEEQPNKDEKIREAKERMPKSDKDKEKLKKEEKAKDEKFRIIVANVESKSTQEREKEKEPSKERDLAKEMK-SKENVKGGEKAPVSGSLKSPISRTDITE-PERE-KRRKVDSHPSPSHSSTIK---------------------------DSLVKLKESSAKLYINHIPPLLCKSKEREADKKDLDKSRERSREREKKEEKDRKERKRD-YSNNDREAPLDLIK-RRKDENGILGVSKHKSESPCESLYPNEKDKEKMKSKSSGKEKGD--SFKPEKIDKISSG-KKESGHDKEKIEKKEKWDGSGDKEEKKHHKTSDKHR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B1AZI6-1", "uniprot_id": "THOC2_MOUSE", "id": "B1AZI6-1", "name": "THO complex subunit 2", "aln": "---------------------------------------------MAAAA-------VVVPAEWIKNWEKSGRGEFLHLCRILSENKS------HDSSTYRDFQQALYELSYHVIKGNLKHEQASSVLNDISEFREDMPSILADVFCILDIETNCLEE--KSKRDYFTQLVLACLYLVSDTVLKERLDPETLESLGLIKQSQQFNQKSVKIKTKLFYKQQKFNLLREENEGYAKLIAELGQDLSGN---ITSDLILENIKSLIGCFNLDPNRVLDVILEVFECRPEH-DDFFISLLES----------------YMSMCEPQTLCHILGFKFKFYQEPSGETPSSLYR-VAAVLLQFNLIDLDDLYVHLLPADNCIMDEYKREIVEAKQIVRK------LTMVVLSSEKLDERDKEK--DKDDEKVEKPPDNQ--------------------KLGLLEALLKVGDWQHAQNIMDQMPPYYAASHKLIALAICKLIHITVEPLYRR----------------VGVPKGAKGSPVSALQNKR--APKQVESFEDLRRDVFNMFCY-LGPHLSHDPILFAKVVRIGKS------------FMKEFQSDGSKQEDKE-KTEVILSCLLSITDQVLLPSLSLMDCNACMSEELWGMFKTFPYQHRYRLYGQWKNETYNGHPLLVKVKAQTIDRAKYIMKRLTKENVKPSGRQIGKLSHSNPTILFDYILSQIQKYDNLITPVVDSLKYLTSLNYDVLAYCIIEALANPEKERMKHDDTTISSWLQSLASFCGAVFRKYP-IDLAGLLQYVANQLKAGKSFDLLILKEVVQKMAGIEITEEMTMEQLEAMTGGEQLKAEGG--YFGQIRNTKKSSQRLKDALLDHDLALPLCLLMAQQRNGVIFQE-GGEKHLKLVGKLYDQCHDTLVQFGGFLASNLSTEDYIKRVPSIDVLCNEFHTPHDAAFFLSRPMYAHHISSKYDELKKSEKGSKQQ---HKVHKYITSCEMVMAPVHEAVVSLHVSKVWDDISPQFYATFWSLTMYDLAVPHTSYEREVNKLKVQMKAIDDNQEMPPNKKKKEKERCTALQDKLLEEEKKQMEHVQRVLQRLKLEKDNWLLAKS---TKNETITKFLQLCIFPRCIFSAIDAVYCARFVELVHQQKTPNFSTLLCYDRVFSDIIYTVASCTENEASRYGRFLCCMLETVTRWHSDRATYEKECGNYPGFLTILRAT-GFDGGNKADQLDYENFRHVVHKWHYKLTKASVHCLETGEYTHIRNILIVLTKILPWYPKVLNLGQALERRVNKICQEEKEKRPDLYALAMGYSGQLKSRKSHMIPENEFHHKDPPPRNAVASVQ-NGPGGGTSSSSIGNASKS-DESGAEETDKSRERSQCGTKAVNKASSTTPKGNS--SNGNSGSNSNKAVKENDKEKVKEKEKEKKEKTPATTPEARALGKDSKEKPKEERPNKEDKARETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPIVESKSTQEREREKEPSRERDVAKEMK-SKENVKGGEKTPVSGSLKSPVPRSDISE-PDREQKRRKIDSHPSPSHSSTVK---------------------------DSLIDLKDSSAKLYINHNPPPLSKSKEREMDKKDLDKSRERSREREKKDEKDRKERKRD-HSNNDREVPPDITK-RRKEENGTMGVSKHKSESPCESQYPNEKDKEKNKSKSSGKEKSSSDSFKSEKMDKISSGGKKESRHDKEKIEKKEKRDSSGGKEEKKHHKSSDKHR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K8V3-1", "uniprot_id": "A0A0G2K8V3_RAT", "id": "A0A0G2K8V3-1", "name": "THO complex subunit 2", "aln": "---------------------------------------------MAAAT-------VVVPAEWIKNWEKSGRGDFLHLCRILSENKS------HDSSTYRDFQQALYELSYHVIKGNLKHEQASSVLNDISEFREDMPSILADVFCILDIETNCLEE--KSKRDYFTQLVLACLYLVSDTVLKERLDPETLESLGLIKQSQQFNQKSVKIKTKLFYKQQKFNLLREENEGYAKLIAELGQDLSGT---ITSDLILENIKSLIGCFNLDPNRVLDVILEVFECRPEH-DDFFISLLES----------------YMSMCEPQTLCHILGFKFKFYQEPSGETPSSLYR-VAAVLLQFNLIDLDDLYVHLLPADNCIMDEYKREIVEAKQIVRK------LTMVVLSSEKLDERDKEK--DKDDEKVEKPPDNQ--------------------KLGLLEALLKIGDWQHAQNIMDQMPPYYAASHKLIALAICKLIHITVEPLYRR----------------VGVPKGAKGSPVSALQNKR--APKQVESFEDLRRDVFNMFCY-LGPHLSHDPILFAKVVRIGKS------------FMKEFQSDGSKQEDKE-KTEVILSCLLSITDQVLLPSLSLMDCNACMSEELWGMFKTFPYQHRYRLYGQWKNETYNGHPLLVKVKAQTIDRAKYIMKRLTKENVKPSGRQIGKLSHSNPTILFDYILSQIQKYDNLITPVVDSLKYLTSLNYDVLAYCIIEALANPEKERMKHDDTTISSWLQSLASFCGAVFRKYP-IDLAGLLQYVANQLKAGKSFDLLILKEVVQKMAGIEITEEMTMEQLEAMTGGEQLKAEGG--YFGQIRNTKKSSQRLKDALLDHDLALPLCLLMAQQRNGVIFQE-GGEKHLKLVGKLYDQCHDTLVQFGGFLASNLSTEDYIKRVPSIDVLCNEFHTPHDAAFFLSRPMYAHHISSKYDELKKSEKGSKQQ---HKVHKYITSCEMVMAPVHEAVVSLHVAKVWDDISPQFYATFWSLTMYDLAVPHTSYEREVNKLKVQMKAIDDNQEMPPNKKKKEKERCTALQDKLLEEEKKQMEHVQRVLQRLKLEKDNWLLAKS---TKNETITKFLQLCIFPRCIFSAIDAVYCARFVELVHQQKTPNFSTLLCYDRVFSDIIYTVASCTENEASRYGRFLCCMLETVTRWHSDRATYEKECGNYPGFLTILRAT-GFDGGNKADQLDYENFRHVVHKWHYKLTKASVHCLETGEYTHIRNILIVLTKILPWYPKVLNLGQALERRVNKICQEEKEKRPDLYALAMGYSGQLKSRKSHMIPENEFHHKDPPPRNAVASVQ-NGPGGGTSSSSIGSASKS-DESGAEETDKSRERSQCGTKAVNKASSTTPKGNS--SNGNSGSNSNKAVKENDKEKVKEKEKEKKEKTPATTPEARVLGKESKEKPKEERPNKDDKARETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPSVESKSTQEREREKEPSRERDVAKEMK-SKENVKGGEKPPVSGSLKSPVPRSDISE-PDREQKRRKIDTHPSPSHSSTVKVTDILPKVPLGSENYASSPVISIHFLQDSLIDLKDSSAKLYINHNPPPLSKSKEREMDKKDLDKSRERSREREKKDEKDRKERKRD-HSNNDREVPPDITK-RRKEENGTMGVSKHKSESPCESQYPNEKDKEKNKSKSSGKEKGSSDSFKSEKMDKISSGGKKESRHDKEKIEKKEKRDSSGGKEEKKHHKSSDKHR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NI27-1", "uniprot_id": "THOC2_HUMAN", "id": "Q8NI27-1", "name": "THO complex subunit 2", "aln": "---------------------------------------------MAAAA-------VVVPAEWIKNWEKSGRGEFLHLCRILSENKS------HDSSTYRDFQQALYELSYHVIKGNLKHEQASNVLSDISEFREDMPSILADVFCILDIETNCLEE--KSKRDYFTQLVLACLYLVSDTVLKERLDPETLESLGLIKQSQQFNQKSVKIKTKLFYKQQKFNLLREENEGYAKLIAELGQDLSGS---ITSDLILENIKSLIGCFNLDPNRVLDVILEVFECRPEH-DDFFISLLES----------------YMSMCEPQTLCHILGFKFKFYQEPNGETPSSLYR-VAAVLLQFNLIDLDDLYVHLLPADNCIMDEHKREIAEAKQIVRK------LTMVVLSSEKMDEREKEK--EKEEEKVEKPPDNQ--------------------KLGLLEALLKIGDWQHAQNIMDQMPPYYAASHKLIALAICKLIHITIEPLYRR----------------VGVPKGAKGSPVNALQNKR--APKQAESFEDLRRDVFNMFCY-LGPHLSHDPILFAKVVRIGKS------------FMKEFQSDGSKQEDKE-KTEVILSCLLSITDQVLLPSLSLMDCNACMSEELWGMFKTFPYQHRYRLYGQWKNETYNSHPLLVKVKAQTIDRAKYIMKRLTKENVKPSGRQIGKLSHSNPTILFDYILSQIQKYDNLITPVVDSLKYLTSLNYDVLAYCIIEALANPEKERMKHDDTTISSWLQSLASFCGAVFRKYP-IDLAGLLQYVANQLKAGKSFDLLILKEVVQKMAGIEITEEMTMEQLEAMTGGEQLKAEGG--YFGQIRNTKKSSQRLKDALLDHDLALPLCLLMAQQRNGVIFQE-GGEKHLKLVGKLYDQCHDTLVQFGGFLASNLSTEDYIKRVPSIDVLCNEFHTPHDAAFFLSRPMYAHHISSKYDELKKSEKGSKQQ---HKVHKYITSCEMVMAPVHEAVVSLHVSKVWDDISPQFYATFWSLTMYDLAVPHTSYEREVNKLKVQMKAIDDNQEMPPNKKKKEKERCTALQDKLLEEEKKQMEHVQRVLQRLKLEKDNWLLAKS---TKNETITKFLQLCIFPRCIFSAIDAVYCARFVELVHQQKTPNFSTLLCYDRVFSDIIYTVASCTENEASRYGRFLCCMLETVTRWHSDRATYEKECGNYPGFLTILRAT-GFDGGNKADQLDYENFRHVVHKWHYKLTKASVHCLETGEYTHIRNILIVLTKILPWYPKVLNLGQALERRVHKICQEEKEKRPDLYALAMGYSGQLKSRKSYMIPENEFHHKDPPPRNAVASVQ-NGPGGGPSSSSIGSASKS-DESSTEETDKSRERSQCGVKAVNKASSTTPKGNS--SNGNSGSNSNKAVKENDKEKGKEKEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKDEKARETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQEREREKEPSRERDIAKEMK-SKENVKGGEKTPVSGSLKSPVPRSDIPE-PEREQKRRKIDTHPSPSHSSTVK---------------------------DSLIELKESSAKLYINHTPPPLSKSKEREMDKKDLDKSRERSREREKKDEKDRKERKRD-HSNNDREVPPDLTK-RRKEENGTMGVSKHKSESPCESPYPNEKDKEKNKSKSSGKEKGS-DSFKSEKMDKISSGGKKESRHDKEKIEKKEKRDSSGGKEEKKHHKSSDKHR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E2QCS8-1", "uniprot_id": "E2QCS8_DROME", "id": "E2QCS8-1", "name": "THO complex subunit 2", "aln": "MQRSTDRLRRLKKLKSVTGAQDGVGGGDAAATADNRTSASSDTNGAAASSGAGGNQPGTLNPEVFKHLDKSGRSEFLKYLKHQLQDAADTPVYDKNGVFKQGISNAIYQLLWQTLRFTHKKDIVLHLLLEVVALHADFPSLIVDVVNILDSETSLITDGLQEERHAFVQLVKDLDRVIPESLLKERLEIDTLQEAGIVK-NKSFYSKFIKVKTKLYYKQRRFNLFREESEGFAKLITELNQEFDEN---TTPESIMDIIKSLIGCFNLDPNRVLDIIIESFETRPDR-WNLFIPLLRS----------------YMPTGA--IICEVLGYKFCHFKDS--RTPRSLYH-VCALLLKHGVIALNDVYVWLTPNDGSIKADWEEDLADAREMVRK------LNLIQTN-KKEDEKDPPPPPSVKKFNEEKYNANQ--------------------KFGLCEALLKVGDWENAYKIIQKLPEQAVVLQEPIARAIADLIHLSVENIYYKKC--------------FKAPAGRRPSRNRLYEDSKLVAKMQAKEFGDLRKYTWPMANV-LGPAMHYDTVLMYKLIRIMRK------------LVVDMGVDSLNGPPPNSEAEQHYYDIMSSLDACILPSLLYLDNNCSMSEEIWAVLKYFPYHFRYSLYARWKNDSYQLHPNLIRRCGLAQRDIKALMKRVSKENVKQLGRLVGKYSHCAPGLLFDYILLQIQIYDNLIGPVCDLLKYLTALSFDCLGYCIIESLTLTGRLRFKDDGTSLSLWLQSLASFCGTIYKKYS-IELSGLLQYVANQLKSQKSLDLLILREIVHKMAGVESCEEMTNDQLQAMCGGEQLRGEAG--YFSQVRNTKKSSNRLKEALANNDLAVAICLLMAQQKHCVIYRETAAHSHLKLVGNLYDQCQDTLVQFGTFLGSTYSVDEYVERLPSIITMLREYHINTDVAFFLARPMFTHQINQKYDQLRKDDPNAKKLTTTQKLQKYLEATQLIMNPIVESVRPLHSSKVWEDISPQFLVTFWSLSMYDLHVPNESYQREVAKLKQLAQQAAEGKDSNQSKNKKEQERYIALMEKLNDERKKQHEHVDKISQRLQEQKDSWFLLRSGKSAKNDTITQFLQLCLFPRCTFTALDALYCAKFVHTIHNLKTSNFSTLLCYDRIFCDITYSVTSCTEGEATRYGRFLCAMLETVMRWHADQAVFNKECANYPGFVTKFRVSNQFSEAN--DHVGYENYRHVCHKWHYKITKAIVFCLDSKDFMQIRNALIILMRILPHYPVLSKLAQIIERKVDKVREEEKTKRPDLYAIASSYIGQLKLKTPHMLKESVFHQIAERP-NKESPTSVGAPAAATRSDKLSPTSPSGNTQGTRAPGGAAPFYNSEQKSVIKEPDAKAASTTRESKSQRGEGNNVTLVSTATSTASNNERESKQRDLPAPRESQSRSKDDQQEQANNGSNGSRQSESRNRDVERDRHDQQDQRSISSHRSSRDIVRVKERTEAELHQRSRERSQRLEELEAQQRKREKTSRRGGEERIRHGDGVETVDLVGSTDNRHYEEFEGRMRDLSSVSNESNGS-----------------------------LHHRQRSHETIEFEKVD---SKRRKLESSTSSSKKVEELVDSVKKARALKTKERNKDKLSDEERDARKDRKLGRKRDRVDESNSNEHKRRREGQNGEEELRDRERHREKSP-RERSH------EKFDRERGGASGSRAEERQYISKSAR--------------SSRVNY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53552-1", "uniprot_id": "THO2_YEAST", "id": "P53552-1", "name": "THO complex subunit 2", "aln": "--------------------------MAEQTLLSKLNALSQKVIPPASPS-----QASILTEEVIRNWPERSKTLCSDFTALESNDEK------------EDWLRTLFIELFDFIN--KNDENSPLKLSDVASFTNELVNHERQVSQASIVGKMFIAVS--STVPNINDLTTISLCKLIPSLHEELFKFSWISSKLLNKEQTTLLRHLLKKSK---YELKKYNLLVENSVGYGQLVALLILAYYDPDNFSKVSAYLKEIYHIMGKYSLDSIRTLDVILNVSSQFITEGYKFFIALLRKSDSWPSSHVANNSNYSSLNEGGNMIAANIISFNLSQYNEEVDKENYERYMDMCCILLKNGFVNFYSIWDNVKPEMEFLQEYIQNLETELEEESTKGVENPLAMAAALSTENETDEDNALVVNDDVNMKDKISEETNADIESKGKQKTQQDILLFGKIKLLERLLIHGCVIPVIHVLKQYP-KVLYVSESLSRYLGRVFEYLLNPLYTSMTSSGESKDMATALMITRIDNGILAHKPRLIHKYKTHEPFESLELNSSYVFYYSEWNSNLTPFASVNDLFENSHIYLSIIGPYLGRIPTLLSKISRIGVADIQKNHGSESLHVTIDKWIDYVRKFIFPATSLLQNNPIATSEVYELMKFFPFEKRYFIYNEMMTKLSQDILPLKVSFNKAEREAKSILKALSIDTIAKESRRFAKLISTNPLASLVPAVKQIENYDKVSELVVYTTKYFNDFAYDVLQFVLLLRLTYN-RPAVQFDGVNQAMWVQRLSIFIAGLAKNCPNMDISNIITYILKTLHNGNIIAVSILKELIITVGGIRDLNEVNMKQLLMLNSGSPLKQYARHLIYDFRDDNSVISSRLTSFFTDQSAISEIILLLYTLNLKANTQN----SHYKILSTRCDEMNTLLWSFIELIKHCLKGKAFEENVLPFVELNNRFHLSTPWTFHIWRDYLDNQLNS---------------------NENFSIDELIEGAEFSDVD-------LTKISKDLFTTFWRLSLYDIHFDKSLYDERKNALSGENTGHMSNRKKHLIQN---------QIKDILVTGISHQRAFKKTSEFISEKSNVWNKDCG-----EDQIKIFLQNCVVPRVLFSPSDALFSSFFIFMAFR--TENLMSILNTCITSNILKTLLFCCTSSEAGNLGLFFTDVLKKLEKMRLNGDFN-------------------------------DQASRKLYEWHSVITEQVIDLLSEKNYMSIRNGIEFMKHVTSVFPVVKAHIQLVYTTLEENLINEE--REDIKLPSSALIGHLKARLKDALELDEFCTLTEEEAEQKRIREMELEEIKNYETACQNEQKQVALRKQLELNKSQRLQNDPPKSVASGSAGLNSKDRYTYSRNEPVIPTKPSSSQWSYSKVTRHVDDINHYLATNHLQKAISLVENDDETRN-LRKLSKQNMPIFDFRNSTLEIFERYFRTLIQNPQNPDFAEKIDSLKRYIKNISREPYPDTTSSYSEAAAPEYTKRSSRYSGNAGGKDGYGSSNYRGPSNDRSAPKNIKPISSYAHKRSELP-----------------------------TRPSKSKTYNDRSRALRPTGPDRGDGFDQRDNRLREEYKKNSSQRSQLRFPEKPFQEGKDSSKANPYQASS-YKRDSPSENEEKPNKRFKKDETIRNKFQTQDYRNTRDSGAAHRANENQRYNGNRKSNTQALPQGPKGGNYVSRYQR--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.: : * :: : .: :. .. .::: :. :. : : * :: : :: :: . : . : :* : :: :* :. . : . : * . : : :* .. *: :::**: *:. *:.:*:. * . . :. : ::* :.**. *.**:*:: . . .:**.**. : ..::.::: ::: . . * ..:**: ..: : .:: : * : :. .: .: * :: :.: . . :* : *: * * ** * . ::.: * : :: : ::. :: :* * .. : : .: . : * * : :: . : : : : . : . . . :. ::*: :: * :.*:: ::* **:. ** :* . .. : * : * ::* :: :.: .* ..* * : : **: **:: * **:. : :* * : :: *: : .: *... : *:* *: * . : :: . ::::.:: *: : *: : : : **:*:: .:.*:. :*:. .** : .*. *: . :. :.. *.**.. : ::. : **: . . :: .* *::.. *: : * .* :: . . : :.: .: : ..:* :*.: * :::.. :: : ::: . . * .** :: .*** *::**: . : *:.. *. ..:. :: ..: .: . ..: . :. :.: * . :: *. *** *:.** *:. *:::.: *: .. * *: ::* : : . *..** . * *: :*:.: : : : :: : ::** :*: : *. :: *** : .: :: . :* : * : :.: :*: : *: : *:** : : . * : . . : : *:. . . . : . . . . .. :. :: .. : . ::. .: . : . .. : . :. : . . . :. .:. : : . : ... .. . . . . .: .* :: . . * .: : . . .* . .: *: : .:..: : ::: . . :* :. : : :: . :.. : : : . . : :.: : ", "identical_positions": 147, "similar_positions": 517, "identity": "8.25%" }, { "cls_id": "homologset.agr.SGD:S000005085", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920P6-1", "uniprot_id": "ADA_RAT", "id": "Q920P6-1", "name": "Adenosine deaminase", "aln": "-MAQTPAFNKPKVELHVHLDGAIKPETILYYGKKRGIDLPADTVEGLRNIIGMDKPLSLPDFLAKFDYYMPAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVDPIPWNQAEGDLTPDEVVDLVNQGLQEGEQAF-GIKVRSILCCMRHQ-PSWSPEVLELCKKYHQKTVVAMDLAGDETIEGSSLFPGHVEAYEGAVKDGIHRTVHAGEVGSAEVVREAVDILKTERVGHGYHTIEDEALYNRLLKENMHFEVCPWSSYLTGAWNPK-TTHAVVRFKDDQANYSLNSDDPLIFKSTVDTDYQMVKKDMG-FTEEEFKRLNINAAKSSFLPEDEKKELLERLYKEYQ-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P03958-1", "uniprot_id": "ADA_MOUSE", "id": "P03958-1", "name": "Adenosine deaminase", "aln": "-MAQTPAFNKPKVELHVHLDGAIKPETILYFGKKRGIALPADTVEELRNIIGMDKPLSLPGFLAKFDYYMPVIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVDPMPWNQTEGDVTPDDVVDLVNQGLQEGEQAF-GIKVRSILCCMRHQ-PSWSLEVLELCKKYNQKTVVAMDLAGDETIEGSSLFPGHVEAYEGAVKNGIHRTVHAGEVGSPEVVREAVDILKTERVGHGYHTIEDEALYNRLLKENMHFEVCPWSSYLTGAWDPK-TTHAVVRFKNDKANYSLNTDDPLIFKSTLDTDYQMTKKDMG-FTEEEFKRLNINAAKSSFLPEEEKKELLERLYREYQ-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00813-1", "uniprot_id": "ADA_HUMAN", "id": "P00813-1", "name": "Adenosine deaminase", "aln": "-MAQTPAFDKPKVELHVHLDGSIKPETILYYGRRRGIALPANTAEGLLNVIGMDKPLTLPDFLAKFDYYMPAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEVVALVGQGLQEGERDF-GVKARSILCCMRHQ-PNWSPKVVELCKKYQQQTVVAIDLAGDETIPGSSLLPGHVQAYQEAVKSGIHRTVHAGEVGSAEVVKEAVDILKTERLGHGYHTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPD-TEHAVIRLKNDQANYSLNTDDPLIFKSTLDTDYQMTKRDMG-FTEEEFKRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAGQNL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DG22-1", "uniprot_id": "ADA_DANRE", "id": "Q6DG22-1", "name": "Adenosine deaminase", "aln": "-MNGKPAFDKPKVELHVHLDGAIRLKTVLDVAKRRGISLPVSMEEELKELCTVNEPATLTEFLGKFSHFMHVIAGDREAIKRIAYEFVETKAKEGVIYVEARYSPHFLANKGVEPLPWDQKPGDITPDDVVDLVNQGFKEGEQAF-KTKARSILCCMRHM-PNWSMEVVELCKKFHKDGVVAIDLAGDESMN-CESYPGHKKAFEEAVRSNVHRTVHAGEVGPASVVREAVEVLKAERIGHGYHTLEDQNLYKQLLHQNMHFEMCPVSSRLTGACEPDFTKHPLITFKKDKANYSLNTDDPTIFNSTLNSDYEVVQKYMD-FTEEEFKRLNINAAKSCFLPEKEKEKLLNQLYEAYGMRKSTSF----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53909-1", "uniprot_id": "ADE_YEAST", "id": "P53909-1", "name": "Adenine deaminase", "aln": "MVSVEFLQELPKCEHHLHLEGTLEPDLLFPLAKRNDIILPEGFPKSVEELNEKYKKFRDLQDFLDYYYIGTNVLISEQDFFDLAWAYFKKVHKQGLVHAEVFYD------------PQSHTSRGISIETVTKGFQRACDKAFSEF-GITSKLIMCLLRHIEPEECLKTIEEATPFIKDGTISALGLDSAEKPFPPHLFVECYGKAASLNKDLKLTAHAGEEGPAQFVSDALDLLQVTRIDHGINSQYDEELLDRLSRDQTMLTICPLSNVKLQVVQSV-SELPLQKFLDRDVPFSLNSDDPAYFGGYILDVYTQVSKDFPHWDHETWGRIAKNAIKGSWCDDKRKNGLLSRVDEVVTKYSH-------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VHH7-1", "uniprot_id": "ADAL_DROME", "id": "Q9VHH7-1", "name": "Adenosine deaminase-like protein", "aln": "--MEQFLKGLPKVELHAHLNGSLGIKSLCDLGER---LYGTSCKDFLKLCAHFSRFEKDMDACFEKFAFVHELTSTREGLRFATELAIRDFAEDNVQYVEMRTTP--------------KANENYSRRDYLQIVIDAIKAASETYPEITVKLLPSINRAEPVDVAEETVSLAVELARAHPNLILGIDLSGNPGKGRFSDFAPILAQARDKGLKLAIHCAEIENPSEVKEMLHFG-MSRCGHGTFLTPED--IGQLKQRNIAIECCLTSNVKSGTVPSL-EEHHLKRIMEADAPKVICTDDSGVFDTTLTKEFLIAAETFG-LTREQCIDLTLEAVHHSFASEQEQIQMADRVGNYADILVK-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** * * **:*:: . : ..: . . : . . : .: : : .. ::.: :.* : . : . . . . : . : : . * . . :.:. . : . : ..:: : *..* .. * : :.. * .** :: :* : : : * *. . . : : . .. : :**. * : : . . : .* : :* : .: :..: : . : . ", "identical_positions": 23, "similar_positions": 98, "identity": "6.25%" }, { "cls_id": "homologset.agr.SGD:S000005086", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18577-1", "uniprot_id": "RHCE_HUMAN", "id": "P18577-1", "name": "Blood group Rh(CE) polypeptide", "aln": "------------------------------MSSKYPRSVRRCLPLC-----ALTLEAALILLFYFFTHYDASLED---------------------QKGLVASYQVGQDLTVMAALGLG-FLTSNFRRHSWSSVAFNLFMLALGVQWAILLDGFLSQFP--PGKVVITLFSIRLATMSAMSVLISAGAVLGKVNLAQLVVMVLVEVTALGTLRMVISNIFNTDYHMNLRHFYVFAAYFGLTVAWCLPKPLPKGTEDNDQ-----RATIPSLSAMLGALFLWMFWPSVNSALLRSPIQRKNAMFNTYYALAVSVVT----AISGSSLAHPQRKISMTYVHSAVLAGGVAVGTSCHLIPSPWLAMVLGLVAGLISIGGAKCLPVCCNRVLGIHHISVMHSIFSLLGLLGEITYIVLLVLHTVW----------------NGNGMIGFQVLLSIGELSLAIVIALTSGLLTGLLLNLK------------------------------------------IWKAPHVAKYFDDQVFWKFPHLAVGF-----------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02161-1", "uniprot_id": "RHD_HUMAN", "id": "Q02161-1", "name": "Blood group Rh(D) polypeptide", "aln": "------------------------------MSSKYPRSVRRCLPLW-----ALTLEAALILLFYFFTHYDASLED---------------------QKGLVASYQVGQDLTVMAAIGLG-FLTSSFRRHSWSSVAFNLFMLALGVQWAILLDGFLSQFP--SGKVVITLFSIRLATMSALSVLISVDAVLGKVNLAQLVVMVLVEVTALGNLRMVISNIFNTDYHMNMMHIYVFAAYFGLSVAWCLPKPLPEGTEDKDQ-----TATIPSLSAMLGALFLWMFWPSFNSALLRSPIERKNAVFNTYYAVAVSVVT----AISGSSLAHPQGKISKTYVHSAVLAGGVAVGTSCHLIPSPWLAMVLGLVAGLISVGGAKYLPGCCNRVLGIPHSSIMGYNFSLLGLLGEIIYIVLLVLDTVG----------------AGNGMIGFQVLLSIGELSLAIVIALMSGLLTGLLLNLK------------------------------------------IWKAPHEAKYFDDQVFWKFPHLAVGF-----------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CF94-1", "uniprot_id": "RHD_MOUSE", "id": "Q8CF94-1", "name": "Blood group Rh(D) polypeptide", "aln": "------------------------------MGSKYPRSLRCCLPLW-----ALELQTAFSLLFCFFIPHDTAQVD---------------------HR-FMASYQVLRNLTLMAALGFG-FLSSSFRRHSWSSVAFNLFMLALGVQGTILLDHFLGQVL--QWNKINNLSSIQIATMSTLPVLISAGAVLGKVNLVQLTVMVLMEAMAFGAIRFADEKVFKMTEHIIMMHGHVFGAYFGLTVAWWLSRSLPRRVGENAQTEKVQMATSSSLFAMLGTLFLWIFWPAINSALLEG-TKKRNAVFNTYYALAVSAVT----ATSMSALSHPQGKINMVHIHNAVLAGGVAVGAPGCLISSPWISMVLGLIAGLISIWGAKCPRACLNHML--QNSSGIHYTFGLPGLLGALTYYCLQIVTEPK----------------SSDLWIITQTVTHIGALSFAVAMGMVTGLLTGCLLSVR------------------------------------------VWRAPHAAKYFDDQTFWEFPHLAVGF-----------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QUT0-1", "uniprot_id": "RHAG_MOUSE", "id": "Q9QUT0-1", "name": "Ammonium transporter Rh type A", "aln": "--------------------------------------MRFKFPLM-----AISLEVAMIVLFGLFVEYETPQNASQKNASHQNASQQGNTSSSAKKDQFFQLYPLFQDVHVMIFVGFG-FLMTFLKKYGFSGVGFNLFLAALGLQWGTIMQGLLHSHG---KEFHFGIYNMINADFSTATVLISFGAVLGKTSPIQMLIMTILEIAVFAGNEYLVTELFEASDTGASMTIHAFGAYFGLAVAGVLYRPGLRCEHPNDE-----SVYHSDLFAMIGTLFLWIFWPSFNSAIADPGDHQYRAIVNTYMSLAACVIT----AYALSSLVERRGRLDMVHIQNATLAGGVAVGTCADMEIPLYAAMTIGSIAGIISVLGYKFFSPLLANKLMIHDTCGVHNLHGLPGVFGGLASIVAISWG-----------------------MSTASMAMQAAALGSSIGSAIVGGLLTGLILKLP------------------------------------------IWNQPPDEYCYDDSVSWKVPKFRELDNRFFQHANHNHVEHEV-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02094-1", "uniprot_id": "RHAG_HUMAN", "id": "Q02094-1", "name": "Ammonium transporter Rh type A", "aln": "--------------------------------------MRFTFPLM-----AIVLEIAMIVLFGLFVEYET----------DQTVLEQLNITKPTDMGIFFELYPLFQDVHVMIFVGFG-FLMTFLKKYGFSSVGINLLVAALGLQWGTIVQGILQSQG---QKFNIGIKNMINADFSAATVLISFGAVLGKTSPTQMLIMTILEIVFFAHNEYLVSEIFKASDIGASMTIHAFGAYFGLAVAGILYRSGLRKGHENEE-----SAYYSDLFAMIGTLFLWMFWPSFNSAIAEPGDKQCRAIVNTYFSLAACVLT----AFAFSSLVEHRGKLNMVHIQNATLAGGVAVGTCADMAIHPFGSMIIGSIAGMVSVLGYKFLTPLFTTKLRIHDTCGVHNLHGLPGVVGGLAGIVAVAMG-----------------------ASNTSMAMQAAALGSSIGTAVVGGLMTGLILKLP------------------------------------------LWGQPSDQNCYDDSVYWKVPKTR--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BUX5-1", "uniprot_id": "RHBG_MOUSE", "id": "Q8BUX5-1", "name": "Ammonium transporter Rh type B", "aln": "----------------------------MARVPR---HRRLVLPLL-----CLLFQGATALLFAIFVRYNHETDA------ALWHWGN----HSNVDNEFYFRYPSFQDVHVMVFVGFG-FLMVFLQRYGFSSVGFTFLVASLTLQWATLLQGFLHSFH--GGHIHVGVESLINADFCAGAVLISFGAVLGKTGPAQLLLMALLEAVLFSVNEFILLSLLGVRDAGGSMTIHTFGAYFGLFLSWVLYRSQLEKSRHRQS-----SVYNSDLFAMIGTIFLWVFWPSFNSAPTALGDGQHRTVVNTYYSLTASTLS----TFALSALVSGDGRLDMVHVQNAALAGGVVVGTSSEMMLTPFGALAAGFLAGTVSTLGYKFFTPILESRFKLQDTCGVHNLHGMPGVLGAILGVVVAALATHEAYG-DGLQSVFPLIA-KGQRSATSQAVYQLFGMFVTLVFASVGGSLGGLLLRLP------------------------------------------FLDSPPDSQCFEDQVYWEVPGEQETETQRPLRGGESDTRA---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H310-1", "uniprot_id": "RHBG_HUMAN", "id": "Q9H310-1", "name": "Ammonium transporter Rh type B", "aln": "----------------------------MAGSPSRAAGRRLQLPLL-----CLFLQGATAVLFAVFVRYNHKTDA------ALWHRSN----HSNADNEFYFRYPSFQDVHAMVFVGFG-FLMVFLQRYGFSSVGFTFLLAAFALQWSTLVQGFLHSFH--GGHIHVGVESMINADFCAGAVLISFGAVLGKTGPTQLLLMALLEVVLFGINEFVLLHLLGVRDAGGSMTIHTFGAYFGLVLSRVLYRPQLEKSKHRQG-----SVYHSDLFAMIGTIFLWIFWPSFNAALTALGAGQHRTALNTYYSLAASTLG----TFALSALVGEDGRLDMVHIQNAALAGGVVVGTSSEMMLTPFGALAAGFLAGTVSTLGYKFFTPILESKFKVQDTCGVHNLHGMPGVLGALLGVLVAGLATHEAYG-DGLESVFPLIA-EGQRSATSQAMHQLFGLFVTLMFASVGGGLGGLLLKLP------------------------------------------FLDSPPDSQHYEDQVHWQVPGEHEDKAQRPLRVEEADTQA---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QXP0-1", "uniprot_id": "RHCG_MOUSE", "id": "Q9QXP0-1", "name": "Ammonium transporter Rh type C", "aln": "--------------------------------MAWNTNLRGRLPIT-----CLILQVTMVVLFGVFVRYDIQADA------HWWLEKKRKNISSDVENEFYYRYPSFQDVHAMVFVGFG-FLMTFLQRYGFSAVGFNFLLAAFGIQWALLMQGWFHYFE--EGHIVLSVENIIQADFCVASSCVAFGAVLGKVSPMQLLIMTFFQVTLFTVNEFILLNLIEAKDAGGSMTIHTFGAYFGLTVTWILYRKNLDQSKQRQS-----SVYHSDLFAMIGTLFLWIYWPSFNSASSFHGDAQHRAALNTYLSLAASVLT----TVTVSSIVHKKGKLDMVHIQNATLAGGVGVGTAAEMMLTPYGALIVGFFCGIFSTLGFAYLTPFLESRHRIQDTCGIHNLHGIPGIIGGIVGAVTAAYSSPDVYGEPGIVHSFGFGSYKMDWNKRMQGRSQIFGLLLSLAMALVGGIIVGFILKLP------------------------------------------FWGQAADENCFEDSIYWEVHEEVNTVYIPEDLAHKHSTSLVPAMPLVLPTTSASIVPPVPPTPPVSLATSAPSAALVH-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TNN9-1", "uniprot_id": "RHCG_RAT", "id": "Q7TNN9-1", "name": "Ammonium transporter Rh type C", "aln": "--------------------------------MAWNTNLRGRLPIT-----CLILQVTMVVLFGVFVRYDIQADA------HWWLEKKRKNISSDVENEFYYRYPSFEDVHAMVFVGFG-FLMTYLQRYGFSAVGFNFLLAAFGIQWALLMQGWFHFFE--EGHILLSVENLIQADFCVASTCVAFGAVLGKISPMQLLIMTFFQVTLFTVNEFILLNLIEAKDAGGSMTIHTFGAYFGLTVTWILYRKNLEQSKQRQS-----SVYHSDLFAMIGTLFLWIYWPSFNSASSFHGDTQHRAALNTYLSLAASVLT----TVAVSSVIHKKGKLDMVHIQNATLAGGVGVGTAAEMMLTPYGALIVGFFCGILSTLGFAYLSPFLESRLRIQDTCGIHNLHGIPGIIGGIVGAVTAAYSSPDVYGEPGIVHSFGFGGYKADWTKRMQGRSQIFGLLLSLAMALVGGIIVGFILKLP------------------------------------------FWGQASDENCFEDAIYWEVPEEVNTVYIPEDLAHKHSTSLVPAIPLVLSTPSASIVPPVPPTPPASLAT-VTSSSLVH-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBD6-1", "uniprot_id": "RHCG_HUMAN", "id": "Q9UBD6-1", "name": "Ammonium transporter Rh type C", "aln": "--------------------------------MAWNTNLRWRLPLT-----CLLLQVIMVILFGVFVRYDFEADA------HWWSERTHKNLS-DMENEFYYRYPSFQDVHVMVFVGFG-FLMTFLQRYGFSAVGFNFLLAAFGIQWALLMQGWFHFLQ--DRYIVVGVENLINADFCVASVCVAFGAVLGKVSPIQLLIMTFFQVTLFAVNEFILLNLLKVKDAGGSMTIHTFGAYFGLTVTRILYRRNLEQSKERQN-----SVYQSDLFAMIGTLFLWMYWPSFNSAISYHGDSQHRAAINTYCSLAACVLT----SVAISSALHKKGKLDMVHIQNATLAGGVAVGTAAEMMLMPYGALIIGFVCGIISTLGFVYLTPFLESRLHIQDTCGINNLHGIPGIIGGIVGAVTAASASLEVYGKEGLVHSFDFQGFNGDWTARTQGKFQIYGLLVTLAMALMGGIIVGLILRLP------------------------------------------FWGQPSDENCFEDAVYWEMPEGNSTVYIPEDPTFKPSGPSVPSVPMVSPLPMASSVPLVP-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JI14-1", "uniprot_id": "RHCL2_DANRE", "id": "Q8JI14-1", "name": "Ammonium transporter Rh type C-like 2", "aln": "-----MGNCFGSRG-ICDRPK--------------NTNIRLSLPAV-----CFVWQVSMIILFGVFVRYNEEADT------NWVYTKKEKNITSDIENDFYFRYPSFQDVHVMIFVGFG-FLMTFLKRYSFGAVGFNFLIAAFGLQWALLMQGWFSPLG-DDGKIKIGIENLINADFCVASCLIAYGAVLGKVSPVQLLVMTLFGITLYAVEEFIILRVLNAKDAGGSMVIHTFGAYYGLSISRVLYRPNLNKSKHMNG-----SVYHSDVFAMIGTLFLWMFWPSFNSAICNHGDGQHRAAINTYLALASTVLT----TVAISSMFEKTGKLDMVHIQNSTLAGGVAVGTAAEFMLMPYGSLIVGFFCGIISTLGYIYLTPFLEERLKIQDTCGIHNLHAMPGVIGGIVGAISAAAASKEVYGDLGLKNIFSIEGSNVTRLPTVQGGYQAAALCVALCFGIGGGTFVGLVLKLP------------------------------------------IWGDPADEHCFNDEMYWEVPEDEESIIPPVLSYNNHMIPNNKHEEMRETNFAEQS------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TTF1-1", "uniprot_id": "A0AB32TTF1_DANRE", "id": "A0AB32TTF1-1", "name": "", "aln": "MLRMTFLAPFASRSRDCATRKRDATETQRDEQTQTQTDTQRNLPCAPD-RSAGGVKIAMIILFGVFIRYDEESDS------HWIETRKKNNISTDLENDFYYRYPSFQDVHVMIFVGFG-FLMTFLKRYSFGSVGFNFLIAAFGIQWALLMQGWFHSFDKEDLKIKIGVENLINADFCVAGCLIAYGACLGKVSPVQLMVLTLFGVTLYAVEEYIILYVLHVRDAGGSMVIHTFGAYYGLTISWVLYRPFLSQSNHLQR-----SVYHSDVFAMIGTLFLWMFWPSFNSAIADHGDGQHRAAINTYLSLAASVLT----TFALSSLSKKYGKLDMVHIQNATLAGGVAMGTASEFMITPYGSLIVGFCSGIVSTLGYVFLTPLMEKTLKIQDTCGVHNLHAMPGVIGGIVGAVTAACASESVYGHEGLINMFGFEG-KVNRTASVQGGYQAAGIFVAIAFGLVGGALVGGILKLP------------------------------------------IWGDPTDSNCFDDDIYWEVPEEEDENIPAFGHQNMHHVERTPDAHHRSHV-----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41948-1", "uniprot_id": "MEP2_YEAST", "id": "P41948-1", "name": "Ammonium transporter MEP2", "aln": "----------------MSYNFTGTPTGEGTGGNSLTTDLNTQFDLANMGWIGVASAGVWIMVPGIGLLYSGLSRK---------------------KHALSLLWASMMASAVCIFQWFF-WGYSLAFSHNTRGNGFIGTLEFFGFRNVLGAPSSVSSLPDILFAVYQGMFAAVTGALMLGGACERARLFPMMVFLFLWMTIVYCPIACWVWNAEGWLVKLGSLDYAGGLCVHLTSGHGGLVYALILGKRNDPVTRKGMP----KYKPHSVTSVVLGTVFLWFGWMFFNGGSAGNATIRAWYSIMSTNLAAACGGL----TWMVIDYFRCGRKWTTVGLCSGIIAGLVGITPAAGFVP-IWSAVVIGVVTGAG-----CNLAVDLKSLLRIDDGLDCYSIHGVGGCIGSVLTGIFAADYVNATAG-----SYISPIDGGWINHHYKQVGYQLAGICAALAWTVTVTSILLLTMNAIPFLK-------------------------------------LRLSADEEELGTDAAQIGEFTYEESTAYIPEPIRSKTSAQMPPPHENIDDKIVGNTDAEKNSTPSDASSTKNTDHIV---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VFA9-1", "uniprot_id": "Q9VFA9_DROME", "id": "Q9VFA9-1", "name": "Ammonium transporter", "aln": "------------------------------MNNGTVGAPRNHSNYVIPGLYDLSVEDTNWVLTSSFIIFTMQTGFG--------------MLESGCVSIKNEVNIMMKNVIDIVLGGFTYWLFGYGMSFGRGPLSNPFIAIGDFLLDPPVGDALMGQIF---AAFLFQLSFATTATTIVSGAMAERCNFKAYCLFSFLNTAVYCIPAGWVWGEHGFLNKLGAVDIAGSGPVHLIGGASAFASAAMLGPRLGRYSEGYDP-----LPLGNPVNACMGLFVLWWGWLAFNSGSTYGVSGAKWQYAARAAVMTMMGSFGGGFTSSIYSFWRHGGGMDIMDLINGVLGSLVSI-TAGCFLYRAWEALVIGAIGSLF-----CVLAMPLFDRMGVDDPVGASAVHGVCGIWGVIAVGLFADNPIPLDTTNGRSGLFKGGGWYLLGIQTLSALCLACWGVCSTFLLLYVINKIIPIRMDPHEELLGADLTEHRIRHSQIGLSRAISALAPIKVDLKDIAGIQPIGINPGHERSIDQLRAAEDKLQQWQSYLEQVSGSRANVKMDAGQSHADINFKPRTAGNVFNRRIPARKSISGGLYRSNNSELPVIGSVMGQKPEKDPNFAWVD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: . : : .. . . . : . . : : .. .: : * . :* ..** * .*.. : : : .. :.. * : . : : :: * . . ..: * * : : :. : : : : ", "identical_positions": 10, "similar_positions": 55, "identity": "1.61%" }, { "cls_id": "homologset.agr.SGD:S000005091", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZMR4-1", "uniprot_id": "A0A8I5ZMR4_RAT", "id": "A0A8I5ZMR4-1", "name": "U6 snRNA-associated Sm-like protein LSm7", "aln": "MRMHTELWAVEVERSPGVPGPGNRDVGRLNLSPQRPTFQQDKEKK-----KKESILDLSKYIDKTIRVKFQGGREASGILKGFDPLLNLVLDGTIEYMRDPDDQ--YKLTED-TRQLGLVVCRGTSVVLICPQDGMEAIPNPFVQQQDT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQQ8-1", "uniprot_id": "LSM7_MOUSE", "id": "Q9CQQ8-1", "name": "U6 snRNA-associated Sm-like protein LSm7", "aln": "--------------------------------------MADKEKK-----KKESILDLSKYIDKTIRVKFQGGREASGILKGFDPLLNLVLDGTMEYMRDPDDQ--YKLTED-TRQLGLVVCRGTSVVLICPQDGMEAIPNPFVQQQDT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UK45-1", "uniprot_id": "LSM7_HUMAN", "id": "Q9UK45-1", "name": "U6 snRNA-associated Sm-like protein LSm7", "aln": "--------------------------------------MADKEKK-----KKESILDLSKYIDKTIRVKFQGGREASGILKGFDPLLNLVLDGTIEYMRDPDDQ--YKLTED-TRQLGLVVCRGTSVVLICPQDGMEAIPNPFIQQQDA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4FVI7-1", "uniprot_id": "LSM7_DANRE", "id": "A4FVI7-1", "name": "U6 snRNA-associated Sm-like protein LSm7", "aln": "--------------------------------------MADKDKK-----KKESIFDLSKYIDKHIRVKFQGGREASGVLKGFDPLLNLVLDGTIEYMRDPDDQ--YKLTED-TRQLGLVVCRGTSVVLICPQDGMEAIPNPFIQQQDG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJI7-1", "uniprot_id": "Q9VJI7_DROME", "id": "Q9VJI7-1", "name": "U6 snRNA-associated Sm-like protein LSm7", "aln": "--------------------MADKKVGGN---------NDGKEKR-----RKESILDLSKYLEKQIRVKFAGGREASGILKGYDALLNLVLDNTVEYLRDSDEP--YKLTEEQTRSLGLVVCRGTALVLICPQDGVESIANPFITQ---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53905-1", "uniprot_id": "LSM7_YEAST", "id": "P53905-1", "name": "LSM complex subunit LSM7", "aln": "--------------------MHQQHSKSEN--------KPQQQRKKFEGPKREAILDLAKYKDSKIRVKLMGGKLVIGVLKGYDQLMNLVLDDTVEYMSNPDDENNTELISKNARKLGLTVIRGTILVSLSSAEGSDVL---YMQK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::: ::*:*:**:** :. ****: **: . *:***:* *:*****.*:**: :.*: :* .. :*.***.* *** :* :.. :* : : :: : ", "identical_positions": 38, "similar_positions": 39, "identity": "25.5%" }, { "cls_id": "homologset.agr.SGD:S000005092", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D1E6-1", "uniprot_id": "TBCB_MOUSE", "id": "Q9D1E6-1", "name": "Tubulin-folding cofactor B", "aln": "---MEVTGISAPTVMVFISSSLN-SFRSEKRYSRSLTIAEFKCKLELVVGSPASCMELELYGADDKFYSKLDQEDALLG------SYPVDDGCRIHVIDHSGVRLGEYEDVSKVEKY----EISPEAYERRQNTVRSFMKRSKLGPYNEELRAQQEAEAAQRLSEEKAQASAISVGSRCEVRAPDHSLRRGTVMYVGLTDF-KPGYWVGVRYDEPLGKNDGSVNGKRYF-ECQAKYGAFVKPSAVTVGDFPEEDYGLDEM----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99426-1", "uniprot_id": "TBCB_HUMAN", "id": "Q99426-1", "name": "Tubulin-folding cofactor B", "aln": "---MEVTGVSAPTVTVFISSSLN-TFRSEKRYSRSLTIAEFKCKLELLVGSPASCMELELYGVDDKFYSKLDQEDALLG------SYPVDDGCRIHVIDHSGARLGEYEDVSRVEKY----TISQEAYDQRQDTVRSFLKRSKLGRYNEEERAQQEAEAAQRLAEEKAQASSIPVGSRCEVRAAGQSPRRGTVMYVGLTDF-KPGYWIGVRYDEPLGKNDGSVNGKRYF-ECQAKYGAFVKPAVVTVGDFPEEDYGLDEI----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1ZBM2-1", "uniprot_id": "A1ZBM2_DROME", "id": "A1ZBM2-1", "name": "", "aln": "MSTIIETGKSD-FIKVNVSNSHNDAVAFEVKLAKDLTVAQLKTKLEILTGGCAGTMKVQVFKG-DTCVSTMDNNDAQLG------YYANSDGLRLHVVDSFATFS---FDSAPVEKF----ELSKDQYEQRTDSVRNYLKINRMGKYNDEEMQQAEEKKRLQAEEIQKRAELCVLGGRCEVTVPGNPTRRGTIRYNGPLEG-KSGHFIGVEYDEPLGKNNGSFGGKAYF-TCAPNYGGFVSPLSVTVGDFPPEDFNMDDEL---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53904-1", "uniprot_id": "TBCB_YEAST", "id": "P53904-1", "name": "Tubulin-specific chaperone B", "aln": "------------MVRVVIESELV---RTEKELPNSLKLRQFKDRLYHVTGVEPEDMEIVVKRQYDNKEIYSTKKGGAYSNEDEDANFLKGEEELIVVVTDSNAQSISNQLATQAEGIPSMEVISEEDYLRRDQSVLRWKMAHGYGRFNAAQQSQR-AALAKQDEAYAREQLTAAIGRHCRVTVDGSAPREAILRYVGPLPLDVMGTWCGVEFPEAAGKNDGRINGVTLFGPVAPGHGSFVRPRAVEILSKDEESAEVEDVHDDVESDDEI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :... * . ...*.: ::* :* :.* . *:: : *. ::.. . : .: : *: . : .* :* : * :* ::* : * :* * : . :* :*.* . . . *.. : * * * : **.: *. ***:* ..* * . :*.** * * : . *. ::: ", "identical_positions": 39, "similar_positions": 68, "identity": "14.44%" }, { "cls_id": "homologset.agr.SGD:S000005095", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LKL7-1", "uniprot_id": "A0ABK0LKL7_RAT", "id": "A0ABK0LKL7-1", "name": "", "aln": "MASRGGGRGRGRGQLTFNMEAVGIGKGDALPPPTLQ----PSPLFPPLEFHPVPLPAG--------------EEGEYVLALKQELRGAMRQLPYFIRPAVPKRD-VERYSDKYQMSGPIDNAIDWNP-DWRRLPSELK----IRVRKVQKERT-TIILPKRPPKSTEDKEETIQKLETLEKKEE----EVTSEEDE-EKEEE------EEKEEGEEEEYDEEEHEEPSRVDTLRNACA-VLSEGIAEESTGSPTDYPSPRPPAA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0C0-1", "uniprot_id": "RPC7L_MOUSE", "id": "Q8R0C0-1", "name": "DNA-directed RNA polymerase III subunit RPC7-like", "aln": "MASRGGGRGRGRGQLTFNMEAVGIGKGDALPPPTLQ----PSPLFPPLEFHPVPLPAG--------------EEGEYVLALKQELRGAMRQLPYFIRPAVPKRD-VERYSDKYQMSGPIDNAIDWNP-DWRRLPSELK----IRVRKVQKERT-TIILPKRPPKSTDDKEETIQKLETLEKKEE----EVTSEEDE-EKEEE------EEKEEGEEEEYDEEEHEEET-----DYIMS-YFDNG---EDFGGDSDDNMDEAIY-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BT43-1", "uniprot_id": "RPC7L_HUMAN", "id": "Q9BT43-1", "name": "DNA-directed RNA polymerase III subunit RPC7-like", "aln": "MASRGGGRGRGRGQLTFNVEAVGIGKGDALPPPTLQ----PSPLFPPLEFRPVPLPSG--------------EEGEYVLALKQELRGAMRQLPYFIRPAVPKRD-VERYSDKYQMSGPIDNAIDWNP-DWRRLPRELK----IRVRKLQKERI-TILLPKRPPKTTEDKEETIQKLETLEKKEE----EVTSEEDE-EKEEE------EEKEEEEEEEYDEEEHEEET-----DYIMS-YFDNG---EDFGGDSDDNMDEAIY-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N282-1", "uniprot_id": "A0A8M1N282_DANRE", "id": "A0A8M1N282-1", "name": "", "aln": "MA------GRGRGQLTFSVEIVGIGKGENLPPSCIQ----PTPLFPPLDQKPVPLQAG--------------EEAEYMLALKQEFRGAMKTLPFYIRPAAPKKD-VERYSDKYQKNESFDNSLEWKP-DWRRLPKELR----VREKRPQRDK--SQAVPKRAKQARVDKEEIIRKLETLEQKEK----EGSSDEEEGEKKKP------EEEEAEAENEYDEEEFEDET-----DYIMS-YFENG---EEFGGDSDENMDEAIY-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N2F0-1", "uniprot_id": "A0A8M1N2F0_DANRE", "id": "A0A8M1N2F0-1", "name": "DNA-directed RNA polymerase III subunit", "aln": "MAGMS--RGRGRNQFTFNVDALGFGRGDSLPTTTHT----PSPLFPPMQFQPVPLHTG--------------EEVEYMLALKQELRASSKNLPFHIRAARTKRD-VSRYSDKYQTGEPKNNTIEWSP-DWSRLPKELC----IKVRKPQKTITGTKQQLKQRPKVAASKEDILQKLETLEKEEV----HSEEEEDEGKKKKQND---DEEEEPEVEEDYDEEELEDET-----DYIAS-YFDNG---EDFGGDSDDNMDEAVY-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6NXY9-1", "uniprot_id": "RPC7_MOUSE", "id": "Q6NXY9-1", "name": "DNA-directed RNA polymerase III subunit RPC7", "aln": "MAGN---KGRGRAAYTFNIEAVGFSRGEKLPDVVLK----PPPLFPDTDYKPVPLKTG--------------EDEDYMLALKQELRETVKRLPYFIEPPEEKQDDIERYSKRYMKVYK----EEWVP-DWRRLPREMM----PRKKCKKGDPKSKPSKAAAKATSLINSADVLKTIEELEKRGEGERSDEENEEKEGSKEKDKD-DEEDGEEDAEQEDYDEEEQEEEN-----DYINS-YFDNG---DDFGVDSDDNMDEATY-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A1K1-1", "uniprot_id": "D4A1K1_RAT", "id": "D4A1K1-1", "name": "", "aln": "MAGN---KGRGRAAYTFNIEAVGFSRGEKLPDVVLK----PPPLFPDTDYKPVPLKTG--------------EDEDYMLALKQELRETVKRLPYFIETPEEKQDDIERYSKRYMKVYK----EEWEP-DWRRLPREMM----PRKKCKKADPKSKAAKATSKGTTLMNSTDVLKKIEELERRGEGERSDEENDEKEGSKEKEKD-EEEDGEEDAEQEEYDEEEQEEEN-----DYINS-YFDNG---DDFVVDSDDNMDEATY-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15318-1", "uniprot_id": "RPC7_HUMAN", "id": "O15318-1", "name": "DNA-directed RNA polymerase III subunit RPC7", "aln": "MAGN---KGRGRAAYTFNIEAVGFSKGEKLPDVVLK----PPPLFPDTDYKPVPLKTG--------------EGEEYMLALKQELRETMKRMPYFIETPEERQD-IERYSKRYMKVYK----EEWIP-DWRRLPREMM----PRNKCKKAGPKPKKAKDAGKGTPLTNTEDVLKKMEELEKRGDGEKSDEENEEKEGSKEKSKEGDDDDDDDAAEQEEYDEEEQEEEN-----DYINS-YFEDG---DDFGADSDDNMDEATY-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TV05-1", "uniprot_id": "A0AB32TV05_DANRE", "id": "A0AB32TV05-1", "name": "", "aln": "MAG----KGRGVAAFSFNIESLGLTRG-SMPETQRG----PAPLFPQIEYKPGPLKAG--------------EDEDYMRALKQEMRGRMKDLPFNIKHHAGKGD-VERYKEKYTREIKKLEDEDWTP-DWNRLPKELK----PQKSIKK---KKRDLKKSVK-ISTKDKEEVLNKLDELEKKGD-VKSDEEDEVK---KEKKED--DEEGEEAEIEGDYD-EEFEEDN-----DYIAS-YFEDG---DDFGGGSDDNMDEATY-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86BI8-1", "uniprot_id": "Q86BI8_DROME", "id": "Q86BI8-1", "name": "DNA-directed RNA polymerase III subunit", "aln": "MAG----RGRGGKTGTLTAEQMAMLGCTKDMPVQTA----PPPTFPPVLNRPTTLETT--------------ATQNYQLLWKEDFLNRMRDSPYYMISASRDAKNLDHKDWREKAMERMKLTAQPDF-NYKAMPQELN----ISSRKRRG--------ADARPNLLTKKTNIEDRLKVLEQKELK---SGGGEQDENKQESDS-----EQEEEEDPEAALDDEMDEDN-----DYGAT-YFDNG---EAFNDEDDNLDDGPVY-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17890-1", "uniprot_id": "RPC7_YEAST", "id": "P17890-1", "name": "DNA-directed RNA polymerase III subunit RPC7", "aln": "MSSYRG-GSRGGGSNYMSNLPFGLGYGDVGKNHITEFPSIPLPINGPITNKERSLAVKYINFGKTVKDGPFYTGSMSLIIDQQENSKSGKRKPNIILDEDDTNDGIERYSDKYLKKRKIGISIDDHPYNLNLFPNELYNVMGINKKKLLAISKFNNADDVFTGTGLQDENIGLSMLAKLKELAEDVDDASTGDGAAKGSKTGEG-----EDDDLADDDFEEDEDEEDDD----DYNAEKYFNNG-DDDDYGDEEDPNEEAAF--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .** :. ..: * * : .* ::: : * : . :.: . : : : :* *: . : *:. : .: .: :* :: :.:* : * . ", "identical_positions": 13, "similar_positions": 41, "identity": "4.92%" }, { "cls_id": "homologset.agr.SGD:S000005097", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R5N4-1", "uniprot_id": "M0R5N4_RAT", "id": "M0R5N4-1", "name": "Prefoldin subunit 4", "aln": "MFFQVAPHTPGSLAQQGSRGTSWGDARLDGLPPRPMVQSKMAATMKKAAA--EDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKHLQNLEDACDDVMLADDDCLMIPYQIGDVFISHSQEETQEMLEDAKKTLQEEINALESRVASIQRVLADLKVQLYAKFGSNINLEADDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQP4-1", "uniprot_id": "PFD4_HUMAN", "id": "Q9NQP4-1", "name": "Prefoldin subunit 4", "aln": "----------------------------------------MAATMKKAAA--EDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFISHSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQLYAKFGSNINLEADES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRL3-1", "uniprot_id": "PFD4_DROME", "id": "Q9VRL3-1", "name": "Probable prefoldin subunit 4", "aln": "------------------------------------MAAKVASGTNKVFQNHDDVHISFEDQQRINRFAKHNARMDDFKAELETKRNELKSLEEALEEIELFDED-EDIPFLVGEVFLSHKLEKTQDMLKETKEQVLKEIAGVEAKAKVIKAEMDELKAHLYQRFGSNISLEAED-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53900-1", "uniprot_id": "PFD4_YEAST", "id": "P53900-1", "name": "Prefoldin subunit 4", "aln": "-------------------------------------MELLPQGQR------NNTQVTFEDQQKINEFSKLIMRKDAIAQELSLQREEKEYLDDVSLEIELIDED-EPVQYKVGDLFIFMKQSKVTAQLEKDAERLDNKIETLEDKQRDIDSRLDALKAILYAKFGDNINLER---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . ::.:::*****:**.*:: * : *:. :::. : *::. :: * *:* : : :*::*: . .:. *:. : : ::* :* : *. : **. ** :**.**.** ", "identical_positions": 30, "similar_positions": 51, "identity": "17.05%" }, { "cls_id": "homologset.agr.SGD:S000005098", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9HCP0-1", "uniprot_id": "KC1G1_HUMAN", "id": "Q9HCP0-1", "name": "Casein kinase I isoform gamma-1", "aln": "MDHPSREK---------------DERQRTTKPMAQRSA-------------------HCSRPSGSSSSSGVL------MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAG----EGLPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDWV------GRPIPTPVGSVHVDSGASAIT-RESHTHRDRPSQQQPLRN-------------------------------------QVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEA--------KCCCFFKRKRKKTAQRHK--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BTH8-1", "uniprot_id": "KC1G1_MOUSE", "id": "Q8BTH8-1", "name": "Casein kinase I isoform gamma-1", "aln": "MDHSNREK---------------DDRQRTTKTMAQRNT-------------------HCSRPSGTSTSSGVL------MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAG----EGLPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYVDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFERKGYTFDYAYDWV------GRPIPTPVGSVHVDSGASAIT-RESHTHRDRPSQQQPLRNQTTSSERRGEWEIQPSRQTNTSYLTSHLAADRHGGSVQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEA--------KCCCFFKRKRKKTAQRHK--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62761-1", "uniprot_id": "KC1G1_RAT", "id": "Q62761-1", "name": "Casein kinase I isoform gamma-1", "aln": "MDHSNREK---------------DDRQRTTKTMAQRNT-------------------HCSRPSGTSTSSGVL------MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAG----EGLPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRSTPIEALCENFPEEMMTYLRYVRRLDFFEKPDYEYLRNLFTDLFERKGYTFDYAYDWV------GRPIPTPVGSVHVDSGASAIT-RESHTHRDRPSQQQPLRN--------------------------------------QPRSLTAEWFVLAPL-SHPPAPT----------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5PRD4-1", "uniprot_id": "KC1G1_DANRE", "id": "Q5PRD4-1", "name": "Casein kinase I isoform gamma-1", "aln": "MDHPREKE---------------ADRPVRSSKVPQGRS-------------------GHSRPSSSSASSGVL------MVGPNFRVGKKIGCGNFGELKLGKNLYTNEYVAIKLEPVKSRAPQLHLEYRFYKTLGSA-----DGLPQVFYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHIIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLRNLFTELFDRKGYAFDYSYDWV------GRQIPTPVGTVHVDSGASAIT-RESHAHRDRPSQHQPLRN-------------------------------------QVVSSTNGELNADDPLAAHSNAPITAQAEVEVVDEA--------KCCCFFKRKRKKNTPRHK--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y6M4-1", "uniprot_id": "KC1G3_HUMAN", "id": "Q9Y6M4-1", "name": "Casein kinase I isoform gamma-3", "aln": "MENKKKDK---------------DKSDDRMARPSGRSG-------------------HNTRGTGSS-SSGVL------MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSG-----DGIPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWI------GKQLPTPVGAVQQDP-ALSSN-REAHQHRDKMQQSKNQSADHRAA--------WDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDET--------KCCCFFKRRKRKTIQRHK--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62763-1", "uniprot_id": "KC1G3_RAT", "id": "Q62763-1", "name": "Casein kinase I isoform gamma-3", "aln": "MDNKKKDK---------------DKSDDRMARPSGRSG-------------------HSTRGTGSS-SSGVL------MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSG-----DGIPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWI------GKQLPTPVGAVQQDP-ALSSN-REAHQHRDKIQQSKNQSADHRAA--------WDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDET--------KCCCFFKRRKRKTIQRHK--------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C4X2-1", "uniprot_id": "KC1G3_MOUSE", "id": "Q8C4X2-1", "name": "Casein kinase I isoform gamma-3", "aln": "MDNKKKDK---------------DKSDDRMARPSGRSG-------------------HSTRGTGSS-SSGVL------MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSG-----DGIPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWI------GKQLPTPVGAVQQDP-ALSSN-REAHQHRDKIQQSKNQ----------------------------------------VVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDETNCQKVLNMWCCCFFKRRKRKTIQRHK--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8BVP5-1", "uniprot_id": "KC1G2_MOUSE", "id": "Q8BVP5-1", "name": "Casein kinase I isoform gamma-2", "aln": "MDFDKKGG------------KGELEEGRRMSKTGTSRS-------------------NHG-VRSSGTSSGVL------MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSTT-----EGVPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCESFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGYVFDYEYDWA------GKPLPTPIGTVHPDVPSQPPH-RDKAQLHTKNQ---------------------------------------------ALNSTNGELNTDDPTAGHSNAPIAAPAEVEVADET--------KCCCFFKRRKRKSLQRHK--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62762-1", "uniprot_id": "KC1G2_RAT", "id": "Q62762-1", "name": "Casein kinase I isoform gamma-2", "aln": "MDFDKKGG------------KGELEEGRRMSKTGTNRS-------------------NHG-VRNSGTSSGVL------MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSTT-----EGVPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCESFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGYVFDYEYDWA------GKPLPTPIGTVHPDVPSQPPH-RDKAQLHTKNQ---------------------------------------------ALNSTNGELNTDDPTAGHSNAPIAAPAEVEVADET--------KCCCFFKRRKRKSLQRHK--------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P78368-1", "uniprot_id": "KC1G2_HUMAN", "id": "P78368-1", "name": "Casein kinase I isoform gamma-2", "aln": "MDFDKKGG------------KGETEEGRRMSKAGGGRS-------------------SHG-IRSSGTSSGVL------MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSAT-----EGVPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDWA------GKPLPTPIGTVHTDLPSQPQL-RDKTQPHSKNQ---------------------------------------------ALNSTNGELNADDPTAGHSNAPITAPAEVEVADET--------KCCCFFKRRKRKSLQRHK--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BIW9-1", "uniprot_id": "A0A8M2BIW9_DANRE", "id": "A0A8M2BIW9-1", "name": "non-specific serine/threonine protein kinase", "aln": "MDFDKRGGGGG---------KGEAEDGKRMSKTGGSRT-------------------GHGGSRGSGNNTGVL------MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGNA-----EGVPQVYYFGPCG-KYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLITRMEFVHTRSLIYRDVKPENFLVGRPGTKRQHTIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCESFP-EMATYLRYVRRLDFFERPDYEYLRKLFTDLFDRNGYVFDYEYDWV------GKPLPTPIGPMPSDTPLQPSN-RDKAQPQTKNQSPEPKGSESQPT-----------PVTNRELLGSHLTADRLGGSVQVMSSTNGEVNTDDPTAGHSNAPITAPAEVEVADDT--------KCCCFFKRRKRKALQRHK--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHL4-1", "uniprot_id": "A0A0B4KHL4_DROME", "id": "A0A0B4KHL4-1", "name": "non-specific serine/threonine protein kinase", "aln": "MQRRERQASGGGPQTTTAGPSAGNVANATTALAGGKSSSN----------------NMYSTRQSVSTTTGVL------MVGPNFRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHADNAPDGIPRIYHLGTCGGRYNAMVLELLGLSLEDLFNICARKFSLKTVLMIAKQLLHRIEYVHSRHLIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGREQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYLRYVRRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDWT------GKTMSTPVGSLQTGHEVIISPNKDRHNVTAKTNAKGGVAAWPDVP--------------KPGATLGNLTPADRHGSVQVVSSTNGELNPDDPTAGHSNTPITQQPEVEVVDET--------KCCCFFKRKKKKSTRQKXLDGVQCSPEREAVTLLRATSHSNSRDSVLNNPSQDYIQQATSQHTLRYPPSASMLTPTPTTNTPTLPL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23292-1", "uniprot_id": "KC12_YEAST", "id": "P23292-1", "name": "Casein kinase I homolog 2", "aln": "MSQVQSPLTATN--------SGLAVNNNTMNSQMPNRSNVRLVNGTLPPSLHVSSNLNHNTGNSSASYSGSQSRDDSTIVGLHYKIGKKIGEGSFGVLFEGTNMINGLPVAIKFEPRKTEAPQLKDEYRTYKILAGT-----PGIPQEYYFGQEG-LHNILVIDLLGPSLEDLFDWCGRRFSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANKVHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEAMGHVFFYFLRGQLPWQGLKAPNNKQKYEKIGEKKRLTNVYDLAQGLPIQFGRYLEIVRNLSFEETPDYEGYRMLLLSVLDDLGETADGQYDWMKLNGGRGWDLSINKKPNLHGYGHPNPPNEKSKRHRSKNHQYSSPDHHHHYN----------QQQQQQQAQAQAQAQAQAKVQQQQLQQAQAQQQANRYQLQPDDSHYDEEREASKLDPT--------SYEAYQQQTQQKYAQQQQKQMQQKSKQFANTGANGQTNKYPYNAQPTANDEQNAKNAAQDRNSNK--SSKGFFSKLGCC-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . . :* :** ::::***** *.** * *.*: .. ****:** *:.****: *** ** *. *:*: :::* * :* :*::*** ******: * * *::***: :* *:: :* :*:: *****:**:***:** . : :*:****:**:* * .*::******:***:***********:*:*******:**:**:*:*****.******** . *::*:***:.** * : *.:. * :: **. **.*.* * ***: * *: .::: * : :** * :. . . .. : . .: : ", "identical_positions": 151, "similar_positions": 94, "identity": "25.72%" }, { "cls_id": "homologset.agr.SGD:S000005099", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BFR6-1", "uniprot_id": "ZFAN1_MOUSE", "id": "Q8BFR6-1", "name": "AN1-type zinc finger protein 1", "aln": "--------MAELDIGQHCQVQHCRQRDFLPFVCDGCSGIFCLEHRSKDSHGCSEVNVVKERPKTDEHKSYSCSFKGCTDVELVAVICPYCEKNFCLRHRHQSD--HDCEKLEVAKPRMAATQKLVRDIVDAKTGGAASKGRKGAKSSGTAAKVALMKLKMHADGDKSLPQTERTYFQVYLPKGSKE------KSKAMFFCLRWSIGKVVDFAASLANLRNENNKLTAK--KLRLCHVPSGEALPLDHTLERWITKEECPLYNGGNVILEYLNDEEQFLKNVDSYLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TCF1-1", "uniprot_id": "ZFAN1_HUMAN", "id": "Q8TCF1-1", "name": "AN1-type zinc finger protein 1", "aln": "--------MAELDIGQHCQVEHCRQRDFLPFVCDDCSGIFCLEHRSRESHGCPEVTVINERLKTDQHTSYPCSFKDCAERELVAVICPYCEKNFCLRHRHQSD--HECEKLEIPKPRMAATQKLVKDIIDSKTGETASKRWKGAKNSETAAKVALMKLKMHADGDKSLPQTERIYFQVFLPKGSKE------KSKPMFFCHRWSIGKAIDFAASLARLKNDNNKFTAK--KLRLCHITSGEALPLDHTLETWIAKEDCPLYNGGNIILEYLNDEEQFCKNVESYLE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZQI4-1", "uniprot_id": "D3ZQI4_RAT", "id": "D3ZQI4-1", "name": "AN1-type zinc finger protein 1", "aln": "--------MAELDIGQHCQVQHCRQRDFLPFVCDGCSGIFCLEHRSKDSHGCPEANVIKERLKTDEHKSYPCSFKGCAEVELVAVICPYCEKNFCLRHRHQSD--HECEKLEIPKPRMAATQKLVRDIVDAKAGGAASKGRKGAKSSRTAAKVALMKLKMHADGDKSLPQKERTSRYTYQ-RGAKR------KAKPCSSAYGGASGR----LWTLQRLLVSGMKTTS-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53899-1", "uniprot_id": "CUZ1_YEAST", "id": "P53899-1", "name": "CDC48-associated ubiquitin-like/zinc finger protein 1", "aln": "MSAAIEKETGMLDVGKHC--AYCRQLDFLPFHCSFCNEDFCSNHRLKEDHHCRWLLEHEEVHKTEKSPSKSRDGSSSNDEAYFKSLLPERASVRIQRVSETREPLRGSNTAKVSSTLNSKTLDKIFKFFQRNEKRKSNNKSKKNFGSSSNKIIQLANLKKIAKGDPKIPMQNRIYIWCYLVDGDETDIAKEDTRMPLYINKMWPVGRAMDYLSIQLNVKSSTLTNSSSNDKFQLCKLKEGKQVSFYNIGASLRVTNEIKDLDTLYLVHNNADEKSN----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **:*:** :*** ***** *. *. ** :** ::.* * :* **:: * . . ... : . : * . * . : : .:. ::... : * . : .:.: : :.: * .* : : * :** *.** .:* :* : * : . . . *: .: . . :: ", "identical_positions": 40, "similar_positions": 64, "identity": "13.99%" }, { "cls_id": "homologset.agr.SGD:S000005100", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A242-1", "uniprot_id": "D4A242_RAT", "id": "D4A242-1", "name": "Insulin-induced gene protein", "aln": "-----MPRLHDHVWSYPSAGAARPYSLPRGMIAAALCPQ------------------GP------GAPEPEPAPQGQREGTAA---FSTRPGSWHHDLVQRS-----LVLFSFGVVLALVLN-LLQIQRNVTLFPDEVIATIFSS---------AWWVP-------PCCGTAAAVVGLLYPCIDSHLG----EPHKFKREWASVMRCIGVFVGINHASAKLDFANNVQLSLTLAALSLGLWWTFDRSLSGLGLGITIAFLATLITQFLVYNGVYQYTSPDFLYIRSWLLCIFFSGGVTVGNIGRQLA-----------HSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08755-1", "uniprot_id": "INSI1_RAT", "id": "Q08755-1", "name": "Insulin-induced gene 1 protein", "aln": "-----MPRLHDHVWSYPSAGAARPYSLPRGMIAAALCPQ------------------GP------GAPEPEPAPRGQREGTAG---FSARPGSWHHDLVQRS-----LVLFSFGVVLALVLN-LLQIQRNVTLFPDEVIATIFSS---------AWWVP-------PCCGTAAAVVGLLYPCIDSHLG----EPHKFKREWASVMRCIAVFVGINHASAKLDFANNVQLSLTLAALSLGLWWTFDRSRSGLGLGITIAFLATLITQFLVYNGVYQYTSPDFLYIRSWLPCIFFSGGVTVGNIGRQLAM----GVPEKPHSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGI3-1", "uniprot_id": "INSI1_MOUSE", "id": "Q8BGI3-1", "name": "Insulin-induced gene 1 protein", "aln": "-----MPRLHDHVWNYPSAGAARPYSLPRGMIAAAACPQ------------------GP------GVPEPEHAPRGQRAGTTG---CSARPGSWHHDLVQRS-----LVLFSFGVVLALVLN-LLQIQRNVTLFPDEVIATIFSS---------AWWVP-------PCCGTAAAVVGLLYPCIDSHLG----EPHKFKREWASVMRCIAVFVGINHASAKLDFANNVQLSLTLAALSLGLWWTFDRSRSGLGLGITIAFLATLITQFLVYNGVYQYTSPDFLYIRSWLPCIFFSGGVTVGNIGRQLAM----GVPEKPHSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15503-1", "uniprot_id": "INSI1_HUMAN", "id": "O15503-1", "name": "Insulin-induced gene 1 protein", "aln": "-----MPRLHDHFWSCSCAHSARRRGPPRASAAGLAAKVGEMINV---------SVSGPSLLAAHGAPDADPAPRGRSAAMSGPEPGSPYPNTWHHRLLQRS-----LVLFSVGVVLALVLN-LLQIQRNVTLFPEEVIATIFSS---------AWWVP-------PCCGTAAAVVGLLYPCIDSHLG----EPHKFKREWASVMRCIAVFVGINHASAKLDFANNVQLSLTLAALSLGLWWTFDRSRSGLGLGITIAFLATLITQFLVYNGVYQYTSPDFLYIRSWLPCIFFSGGVTVGNIGRQLAM----GVPEKPHSD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AV61-1", "uniprot_id": "INSI1_DANRE", "id": "Q8AV61-1", "name": "Insulin-induced gene 1 protein", "aln": "-----MPRLEEHCWSCSCSTSVKTKDLS--SAGWIVCKT----------------------------GEMMSIITSVLSHAYG-----SLHSLQSANLIRRG-----LVLFIVGVVLALVLN-LLQIQRNVTLFPEEVLDTLFSS---------AWWIP-------LCCGTAAAVVGLLYPCLDHHLG----EPHKFKREWASVMRCIAVFVGINHASAKLDFANNVQLSLTLAALSLGLWWTFDRSRSGFGLGLTTALLATLIAQLLVYNGIYQYTSPDFLYVRSWLPCIFFSGGVTVGNIGRQLAM----GSTEKIHND", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q91WG1-1", "uniprot_id": "INSI2_MOUSE", "id": "Q91WG1-1", "name": "Insulin-induced gene 2 protein", "aln": "-------------------------------MAEGETES--------------------------------PRPKKCGPYISS-------VTSQSVNVVIRG-----VVLFFIGVFLALVLN-LLQIQRNVTLFPPDVITSIFSS---------AWWVP-------PCCGTASAVIGLLYPCIDRHLG----EPHKFKREWSSVMRCVAVFVGINHASAKVDFDNNFQFSLTLAALSVGLWWTFDRSRSGFGLGVGIAFLATVVTQLLVYNGVYQYTSPDFLYVRSWLPCIFFAGGITMGNIGRQLAMYECKVIAEKSHQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q80UA9-1", "uniprot_id": "INSI2_RAT", "id": "Q80UA9-1", "name": "Insulin-induced gene 2 protein", "aln": "-------------------------------MAEGETES--------------------------------PRPKKRGPYISS-------VTSQSVNVVIRG-----VVLFFIGVFLALVLN-LLQIQRNVTLFPPDVITSIFSS---------AWWVP-------PCCGTASAVIGLLYPCIDRHLG----EPHKFKREWSSVMRCVAVFVGINHASAKVDFDNNFQFSLTLAALSVGLWWTFDRSRSGFGLGVGIAFLATVVTQLLVYNGVYQYTSPDFLYVRSWLPCIFFAGGITMGNIGRQLAMYECKVIAEKSHQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5U4-1", "uniprot_id": "INSI2_HUMAN", "id": "Q9Y5U4-1", "name": "Insulin-induced gene 2 protein", "aln": "-------------------------------MAEGETES--------------------------------PGPKKCGPYISS-------VTSQSVNLMIRG-----VVLFFIGVFLALVLN-LLQIQRNVTLFPPDVIASIFSS---------AWWVP-------PCCGTASAVIGLLYPCIDRHLG----EPHKFKREWSSVMRCVAVFVGINHASAKVDFDNNIQLSLTLAALSIGLWWTFDRSRSGFGLGVGIAFLATVVTQLLVYNGVYQYTSPDFLYVRSWLPCIFFAGGITMGNIGRQLAMYECKVIAEKSHQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53898-1", "uniprot_id": "NSG2_YEAST", "id": "P53898-1", "name": "Protein NSG2", "aln": "MANRGEPDPKKSTESICSLTKPQLYSLYDDDVVRSEDNEIYEELKRSVSIDSTKYSRDQTIDSTFYLAHKVGGSLPRNTVSSNNLERILSASSIHENFPSRTRQTRQNILHYLQAVLILSLSGFAYHELSRNLHDNHLLHPDFASRPLLLGVKLCNWLSNGVLPNWLGYGVEGLLFGSVVPILDNIFQTEVVKSSVHHDSLTSVIRSINAMLGVTFGIRKIQWNSSLQAAGAWGLLNIILWLFFDGSISMLMSCICIGVGCCISCYKDIIDGS------QFLYFMDFY----FLGSLMFGKLGRYLYS----------H--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * :*. . ..* * *. : : . .*. .:: . *:* . *:. *. . :.* : * :* : :. .: . :**:*.: .::*:... *::: ...* : : . *.: ** ** * * : : .. . : : :* :***. .: * *.: .*::** * * ", "identical_positions": 37, "similar_positions": 71, "identity": "11.53%" }, { "cls_id": "homologset.agr.SGD:S000005101", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60841-1", "uniprot_id": "ENSA_RAT", "id": "P60841-1", "name": "Alpha-endosulfine", "aln": "MSQKQE--EENPAEETGEEKQ------DTQEKEGILPEKAEEAKLKAKYPSLGQKPGG-SDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLPSAG-ADKNLVTGDHIPTPQDLPQRKSSLVT--SKLAGGQVE-------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60840-1", "uniprot_id": "ENSA_MOUSE", "id": "P60840-1", "name": "Alpha-endosulfine", "aln": "MSQKQE--EENPAEETGEEKQ------DTQEKEGILPEKAEEAKLKAKYPSLGQKPGG-SDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLPSAG-ADKNLVTGDHIPTPQDLPQRKSSLVT--SKLAGGQVE-------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43768-1", "uniprot_id": "ENSA_HUMAN", "id": "O43768-1", "name": "Alpha-endosulfine", "aln": "MSQKQE--EENPAEETGEEKQ------DTQEKEGILPERAEEAKLKAKYPSLGQKPGG-SDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLPSAG-PDKNLVTGDHIPTPQDLPQRKSSLVT--SKLAGGQVE-------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56212-1", "uniprot_id": "ARP19_MOUSE", "id": "P56212-1", "name": "cAMP-regulated phosphoprotein 19", "aln": "MSAEVP--EAAS----AEEQK------EMEDKV-TSPEKAEEAKLKARYPHLGQKPGG-SDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQLPAAA-PDKTEVTGDHIPTPQDLPQRKPSLVA--SKLAG-----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q712U5-1", "uniprot_id": "ARP19_RAT", "id": "Q712U5-1", "name": "cAMP-regulated phosphoprotein 19", "aln": "MSAEVP--EAAS----AEEQK------EMEDKV-TSPEKAEEAKLKARYPHLGQKPGG-SDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQLPAAA-PDKTEVTGDHIPTPQDLPQRKPSLVA--SKLAG-----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56211-1", "uniprot_id": "ARP19_HUMAN", "id": "P56211-1", "name": "cAMP-regulated phosphoprotein 19", "aln": "MSAEVP--EAAS----AEEQK------EMEDKV-TSPEKAEEAKLKARYPHLGQKPGG-SDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQLPTAA-PDKTEVTGDHIPTPQDLPQRKPSLVA--SKLAG-----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BF67-1", "uniprot_id": "A2BF67_DANRE", "id": "A2BF67-1", "name": "Alpha-endosulfine", "aln": "MSSDNQ--DTETHPEQVDETQ------ESQDTN-SNPVRTEEAKLKAKYPNLGQKPGG-SDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLPAAAGPDKNIVTGDHIPTPQDLPQRKSSLVT--SKLAG-----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1L8X2-1", "uniprot_id": "ENSA_DANRE", "id": "Q1L8X2-1", "name": "Alpha-endosulfine", "aln": "MSENPDDLELESEEKQCELKSGCVYLQDSPEKT-CNPILSEEAKLKAKYPSLGHKPGG-SDFLMKRLQKGQKYFDSGDYNMAKAKMKSKHVVQSA-AEKSLVTGDHIPTPQDLPQRKNTILT--SKLAG-----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUB8-1", "uniprot_id": "Q9VUB8_DROME", "id": "Q9VUB8-1", "name": "", "aln": "MSSAEE--NSNSPATTPQDTE------TTEQANLTDLEKIEEEKLKSKYPSGMRVPGGHSAFLQKRLQKGQKFFDSGDYQMAKQKGGGVKQVFAN----KVTTGEAIPTPETVPARKTSIIQPCNKFPATS---------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53897-1", "uniprot_id": "IGO1_YEAST", "id": "P53897-1", "name": "mRNA stability protein IGO1", "aln": "MSNENLS-PNSSNPDLTKLNN------GESGTIDTSKFSPNEMKLYKMY---GKLPSK-KDIFKHTMQK-RKYFDSGDYALQKAGIQNNDPINYG--KNNLPLTNPSKLREDIIKRRISTCPSTASTAGVVDNATLIQKEGSISSGPPSSNNGTIGGGSTSSTPVGNHSSSSSSLYTESPIR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . . . :* ** * : *. . :: : :** :*:****** : * . . . : : : *: : . .. ", "identical_positions": 18, "similar_positions": 25, "identity": "9.89%" }, { "cls_id": "homologset.agr.SGD:S000005105", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91VJ4-1", "uniprot_id": "STK38_MOUSE", "id": "Q91VJ4-1", "name": "Serine/threonine-protein kinase 38", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAMTG-STPCSSMSN------------------HTKERVTMTKVTLENFYSNLIAQHEEREMRQKKLEKVMEEEGLKDEEKRLRRSAHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHS--------LPSDFT------------------FQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPVSEKAKGLILRFCCEWEHRIGAP-GVEEIKNNLFFEGVDWEHIRERPAAISIEIKSIDDT-----SNFDEFPES-DILKPT---VTTSSHPETDYKNKDWVFINYTYKRFEGLTARGAIPSYMKAAK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GKQ3-1", "uniprot_id": "A0A8I6GKQ3_RAT", "id": "A0A8I6GKQ3-1", "name": "non-specific serine/threonine protein kinase", "aln": "-----------------------------------------------------------------------------MWAGRRRARAVPLPGKRRRRVAHAQCRPQRPLSPQSEGVTGEPWPLRAAVFSGSWGSSCCPLPSRLGSRAPSASPARRGRSRAARSSRLCRLCRRRPRASLPPGSVFSGSFSLCSPG---------------------------------CPGCPGTPPPGLVELFAMAMTG-STPCSSMSN------------------HTKERVTMTKVTLENFYSNLIAQHEEREMRQKKLEKVMEEEGLKDEEKRLRRSAHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLWVVRMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHS--------LPSDFT------------------FQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPVSEKAKGLILRFCCEWEHRIGAP-GVEEIKSNPFFEGVDWEHIRERPAAISIEIKSIDDT-----SNFDEFPES-DILKPT---VTTSNHPETDYKSKDWVFINYTYKRFEGLTARGAIPSYMKAAK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15208-1", "uniprot_id": "STK38_HUMAN", "id": "Q15208-1", "name": "Serine/threonine-protein kinase 38", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAMTG-STPCSSMSN------------------HTKERVTMTKVTLENFYSNLIAQHEEREMRQKKLEKVMEEEGLKDEEKRLRRSAHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHS--------LPSDFT------------------FQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDLILRFCCEWEHRIGAP-GVEEIKSNSFFEGVDWEHIRERPAAISIEIKSIDDT-----SNFDEFPES-DILKPT---VATSNHPETDYKNKDWVFINYTYKRFEGLTARGAIPSYMKAAK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TGE2-1", "uniprot_id": "A0AB32TGE2_DANRE", "id": "A0AB32TGE2-1", "name": "non-specific serine/threonine protein kinase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATRG-HASSSLMSN------------------HTKERVTMAKVTLENFYSNLITQHEEREMRQQKLEKVMDEEGLPDEEKRVRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLQKEQVAHIRAERDILVQADSLWVVKMFYSFQDKLNLYLLMEFLPGGDMMTLLMKKDTLTEEETQFYVAETVLAIDFIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHS--------QSNDLT------------------FQHMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMGWKETLVFPPEVPISERAKELILRFCCEADHRIGAG-GVDDIKRNAFFEGVDYDHIRERPAAITIEIKSIDDT-----SNFDEFPDS-DILQPTSPVVVSNHHPESDYKNKDWVFINYTYKRFEGLTARGAIPSYMKSGKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7TSE6-1", "uniprot_id": "ST38L_MOUSE", "id": "Q7TSE6-1", "name": "Serine/threonine-protein kinase 38-like", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAMTAGATTTFPMSN------------------HTRERVTVAKLTLENFYSNLILQHEERETRQKKLEVAMEEEGLADEEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKADMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYISETVLAIDAIHQLGFIHRDVKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHN--------PPSDFS------------------FQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGFPPFCSETPQETYRKVMSWKETLAFPPEVPVSEKAKDLILRFCTDSENRIGNG-GVEEIKGHPFFEGVDWGHIRERPAAIPIEIRSIDDT-----SNFDDFPES-DILQPV------PNTTEPDYKSKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2H1-1", "uniprot_id": "ST38L_HUMAN", "id": "Q9Y2H1-1", "name": "Serine/threonine-protein kinase 38-like", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAMTAGTTTTFPMSN------------------HTRERVTVAKLTLENFYSNLILQHEERETRQKKLEVAMEEEGLADEEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKSDMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHN--------PPSDFS------------------FQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILRFCIDSENRIGNS-GVEEIKGHPFFEGVDWEHIRERPAAIPIEIKSIDDT-----SNFDDFPES-DILQPV------PNTTEPDYKSKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NBK5-1", "uniprot_id": "TRC_DROME", "id": "Q9NBK5-1", "name": "Serine/threonine-protein kinase tricornered", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMSSRTQDADGASIRFSD------------------HTLDKATKAKVTLENYYSNLVTQYGERKQRLAKLEAQLKDESLSEAQRQEKRLQHAQKETEYLRLKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLVEADHQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFYISETALAIDSIHKLGFIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQA--------KPSDFIG-----------TCASLSCSPMDSKRRAESWKRNRRALAYSTVGTPDYIAPEVFLQTGYGPACDWWSLGVIMYEMLMGYPPFCSDNPQDTYRKVMNWRETLIFPPEIPISEEAKETIINFCCEADRRLGSQRGLEDLKSVPFFRGVDWEHIRERPAAIPVEVRSIDDT-----SNFDEFPDV-SLEIPS------APIPQGGEIAKDWVFINYTYKRFEVRNLE------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53894-1", "uniprot_id": "CBK1_YEAST", "id": "P53894-1", "name": "Serine/threonine-protein kinase CBK1", "aln": "MYNSSTNHHEGAPTSGHGYYMSQQQDQQHQQQQQYANEMNPYQQIPRPPAAGFSSNYMKEQGSHQSLQEHLQRETGNLGSGFTDVPALNYPATPPPHNNYAASNQMINTPPPSMGGLYRHNNNSQSMVQNGNGSGNAQLPQLSPGQYSIESEYNQNLNGSSSSSPFHQPQTLRSNGSYSSGLRSVKSFQRLQQEQENVQVQQQLSQAQQQNSRQQQQQLQYQQQQQQQQQQQHMQIQQQQQQQQQQQQSQSPVQSGFNNGTISNYMYFERRPDLLTKGTQDKAAAVKLKIENFYQSSVKYAIERNERRVELETELTSHNWSEERKSRQLSSLGKKESQFLRLRRTRLSLEDFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSNYYKKLLQQDEATNGISKPGTYNANTTDTANKRQTMVVDSISLTMSNRQQIQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHADQRLGRHGGADEIKSHPFFRGVDWNTIRQVEAPYIPKLSSITDTRFFPTDELENVPDSPAMAQAAKQREQMTKQGGSAPVKEDLPFIGYTYSRFDYLTRKNAL---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: * ::.: .*:.:**:*.. : **: * :** : ... : .: : .:**:::***:* **.::**.::****:***************::**** * *::* :*:*:.*::****:*. :* *** ::***** ***:********:**:*:: : ::*: *:**::* ***: **:*******:****:*:* :**:*******.**::*:* :::*:.* : .. *..::: ::*::.** :*:************:*: **. *******.**** *:*:*****:.**:**:*:*.:.:** ** :: :* .*: * .: . :.*:* * :::* **.***: **: *. :: ** ** .::::.*: : . :* *:.***.**: . . ", "identical_positions": 190, "similar_positions": 147, "identity": "24.84%" }, { "cls_id": "homologset.agr.SGD:S000005106", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P83883-1", "uniprot_id": "RL36A_RAT", "id": "P83883-1", "name": "Large ribosomal subunit protein eL42", "aln": "--------------MVNVPKTRRTFCK--KCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P83882-1", "uniprot_id": "RL36A_MOUSE", "id": "P83882-1", "name": "Large ribosomal subunit protein eL42", "aln": "--------------MVNVPKTRRTFCK--KCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P83881-1", "uniprot_id": "RL36A_HUMAN", "id": "P83881-1", "name": "Large ribosomal subunit protein eL42", "aln": "--------------MVNVPKTRRTFCK--KCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q969Q0-1", "uniprot_id": "RL36L_HUMAN", "id": "Q969Q0-1", "name": "Ribosomal protein eL42-like", "aln": "--------------MVNVPKTRRTFCK--KCGKHQPHKVTQYKKGKDSLYAQGRRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0R7E5-1", "uniprot_id": "M0R7E5_RAT", "id": "M0R7E5-1", "name": "", "aln": "MWRSLVAHVTATPYVVNVPKTRQTFCK--KCGKHQPHKVTQYKMGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKSTKKNVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKCQVIQF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0A6YW33-1", "uniprot_id": "A0A0A6YW33_MOUSE", "id": "A0A0A6YW33-1", "name": "", "aln": "--------------MVNVPKTRQTFCK--KCGKHQSHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLESVEPNCRSKRMLARKRCEHFELGGDKKRKGQVIQF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61485-1", "uniprot_id": "RL36A_DANRE", "id": "P61485-1", "name": "Large ribosomal subunit protein eL42", "aln": "--------------MVNVPKTRRTYCK--KCKKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLT7-1", "uniprot_id": "Q9VLT7_DROME", "id": "Q9VLT7-1", "name": "", "aln": "--------------MVNVPKQRRTFCK--KCKVHKLHKVTQYKKSKERKGAQGRRRYDRKQQGFGGQTKPIFRKKAKTTKKIVLRMECTE--CKYRKQTPLKRCKHFELGGDKKRKGQMIQF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX27-1", "uniprot_id": "RL44A_YEAST", "id": "P0CX27-1", "name": "Large ribosomal subunit protein eL42A", "aln": "--------------MVNVPKTRKTYCKGKTCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKVVLRLECVK--CKTRAQLTLKRCKHFELGGEKKQKGQALQF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :***** *:*:** .* * ******* .* ***:*******.*:******:*:****:*** ***:*..: *: : . ***:******:**:* * :**", "identical_positions": 64, "similar_positions": 22, "identity": "52.46%" }, { "cls_id": "homologset.agr.SGD:S000005107", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C0D5-1", "uniprot_id": "EFL1_MOUSE", "id": "Q8C0D5-1", "name": "Elongation factor-like GTPase 1", "aln": "MVLSGVDKMIRLQKNTANIRNICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYMDSREDEQVRGITMKSSAISLHYAE-----GHEE-----YLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLRQAWLENIRPVLVINKIDRLIVELKFTPQEAYSHLKNILEQINALTGTLFTSKVLEERAERETESQAKPHSEQGEQVYDWSAGLEDVDDSQLYFSPEQGNVVFTSAIDGWGFGIEHFARIYSQKIGIKKEVLLKTLWGDYYINMKAKKIMKVDQAKGK--KPLFVQLILENIWSLYDAVLK-KDKEKIDKIVTSLGLKIGAREARHSDPKVQINAICSQWLPISHAVLAMVCHKLPSPLDMTSERVEKLLCTGSQTFESLPPETQALKAAFMKCGSEDTAPVIIFVSKMFAVDVKALPQNKPRPLTQEEMAQRRERARQRHAEKLAAA---QGQTSQGPTQDG-----------GALETSPHEDEPRG------------DEPDVASVSRQPVSQEESS-------------------------------------------------------QEAFIAFARVFSGIARRGKKIFVLGPKYSPVDFLQRVPLGFSAPLEDLPPVPHMACCTLENLYLLMGRELEDLEEVPPGNVLGIGGLQDFVLKSATLCSL-PSCPPFIPLNFEATPIVRVAVEPKHPSEMPQLVKGMKLLNQADPCVQVLIQETGEHVLVTAGEVHLQRCLDDLRERFAKIHISVSEPIIPFRETITKPPKVDMVNEEIGRQQKVAVIHQTKEEQSKIPEGIHVDSDGLITIPTPNKLATLSVRAIPLPEEVTRILEENSDLIRSMELLTSS-LNEGRN-TQAIHQKTQEKIWEFKGKLEKHLTGRKWRN-TVDQIWSFGPRKCGPNILVSRSEDFQNSVWSGPAGRESKEASR---FRDFGNSIVSGFQLATLSGPMCEEPLMGVCFVLEKWELNKCAEQGASDKQHQGQCDLAGEGQGGGKTCHVGDENQEQQDVCSEPFEE-TSQKGDSPVIDCYGPFSGQLIATMKEACRYALQVKPQRLMAAMYTCDIMATSDVLGRVYAVLSKREGRVLQEEMKEGTDMFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEVIPSDPFWVPTTEEEYLHFGEKADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSKNK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZXJ5-1", "uniprot_id": "D3ZXJ5_RAT", "id": "D3ZXJ5-1", "name": "Elongation factor-like GTPase 1", "aln": "MVLSGLDKMIQLQKNTANIRNICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYMDSREDEQVRGITMKSSAISLHYAE-----GSEE-----YLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLRQAWLENIRPVLVINKIDRLIVELKFTPQEAYSHLKNILGQINALTGTLFTSKVLEERAERETESQAKSHSEQGDQVYDWSTGLEDVDDSQLYFSPEQGNVVFTSAIDGWGFGIEHFARIYSQKIGIKKEVLLKTLWGDYYINMKAKKIMKVDQAKGK--KPLFVQLILENIWSLYDAVLK-KDKEKVDKIVTSLGLKIGAREARHSDPKVQINAICSQWLPISHAVLAMVCQKLPSPLDMTSERVEKLMCTGSQTFESLPLETQALKAAFMKCGSEDTAPVIIFVSKMFAVDVKALPQNKPRPLTQEEMAQRRERARQRHAEKLAAA---QGQAPQGPTQDG-----------GALETSPQEDEPRG------------EEPDMTSVSRQPAPQEESS-------------------------------------------------------QEAFIAFARVFSGVARRGKKIFVLGPKYSPVDFLQRVPQGFSAPLEDLPPVPHMACCTLENLYLLMGRELEDLEEVPPGNVLGIGGLQDSVLKSATLCSL-PSCPPFIPLNFEATPIVRVAVEPKHPSEMPQLVKGMKLLNQADPCVQILIQETGEHVLVTAGEVHLQRCLDDLRERFAKIHISVSEPIIPFRETITKPPKVDMVNEEIGRQQKVAVIHQTKEEQSKIPEGILVDSDGLITIPTPNKLATLSVRAIPLPEEVTRILEENSDLIRSMELLTSS-LNEGRN-TQAIHQKTQEKIWEFKGKLEKHLTGRKWRN-TVDQIWSFGPRKCGPNILVSRSEDFQSSVWSGPAGRESKEASR---FRDFGNSIVSGFQLATLSGPMCEEPLMGVCFVLEKWELNKCAEPGASDKQSQGQCDLTGEGQEKSKTCPVGDENQEQQDGYSEPFEE-TSQKGDSPVIDCYGPFSGQLIATMKEACRYALQVKPQRLMAAMYTCDIMATSDVLGRVYAVLSKREGRVLQEEMKEGTDMFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEVIPSDPFWVPTTEEEYLHFGEKADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSKNK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z2Z2-1", "uniprot_id": "EFL1_HUMAN", "id": "Q7Z2Z2-1", "name": "Elongation factor-like GTPase 1", "aln": "MVLNSLDKMIQLQKNTANIRNICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYMDSREDEQIRGITMKSSAISLHYAT-----GNEE-----YLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLRQAWLENIRPVLVINKIDRLIVELKFTPQEAYSHLKNILEQINALTGTLFTSKVLEERAERETESQVNPNSEQGEQVYDWSTGLEDTDDSHLYFSPEQGNVVFTSAIDGWGFGIEHFARIYSQKIGIKKEVLMKTLWGDYYINMKAKKIMKGDQAKGK--KPLFVQLILENIWSLYDAVLK-KDKDKIDKIVTSLGLKIGAREARHSDPKVQINAICSQWLPISHAVLAMVCQKLPSPLDITAERVERLMCTGSQTFDSFPPETQALKAAFMKCGSEDTAPVIIFVSKMFAVDAKALPQNKPRPLTQEEIAQRRERARQRHAEKLAAA---QGQAPLEPTQDG-----------SAIETCPKGEEPRG------------DEQQVESMTPKPVLQEENN-------------------------------------------------------QESFIAFARVFSGVARRGKKIFVLGPKYSPLEFLRRVPLGFSAPPDGLPQVPHMAYCALENLYLLMGRELEYLEEVPPGNVLGIGGLQDFVLKSATLCSL-PSCPPFIPLNFEATPIVRVAVEPKHPSEMPQLVKGMKLLNQADPCVQILIQETGEHVLVTAGEVHLQRCLDDLKERFAKIHISVSEPIIPFRETITKPPKVDMVNEEIGKQQKVAVIHQMKEDQSKIPEGIQVDSDGLITITTPNKLATLSVRAMPLPEEVTQILEENSDLIRSMEQLTSS-LNEGEN-THMIHQKTQEKIWEFKGKLEQHLTGRRWRN-IVDQIWSFGPRKCGPNILVNKSEDFQNSVWTGPADKASKEASR---YRDLGNSIVSGFQLATLSGPMCEEPLMGVCFVLEKWDLSKFEEQGAS--------DLAKEGQEENETCSGGNENQELQDGCSEAFEKRTSQKGESPLTDCYGPFSGQLIATMKEACRYALQVKPQRLMAAMYTCDIMATGDVLGRVYAVLSKREGRVLQEEMKEGTDMFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEIIPSDPFWVPTTEEEYLHFGEKADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSKNK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VV61-1", "uniprot_id": "Q9VV61_DROME", "id": "Q9VV61-1", "name": "Ribosome assembly protein 1", "aln": "MPVVEGSDLVLLQRRRQQVRNICILAHVDHGKTTLADSLVASNGIISQRMAGKLRYLDNRSDEQERGITMKSSSISLYYQEAEEMAGNPD-----YLINLIDSPGHVDFSSEVSTAVRLCDGAIVVVDVVEGVGPQTRACLRQIYEEQLKPVLVLNKLDRLILEKQMDPLDAYFHLCQVLEQVNAVLGSIFASDILAKEDITKKD--------------NYESALEEVDDSELYFSPSSGNVIFCSAYDGWAFSVRDFAAMYAKRLEMSRKDLENVLWGDFYYNSKKKEALPGAQEKAK--KPMFVQFVLENIWSLYDIIAIRKDKDKLPGIAEKLGLKLATRDLRLTDPKLQIKAVLGQWLPIDKSVLHMVIQHVPPPHKISDERAQRLLYPANVDLSSLPPETLELKESFTSCDAN-SSNVIAFVSKMTPVHITHLPQNRPKRLTDQEVQQRRDEVRRRIEERKQQS---EQAELEKISQGV-----------EQLSTQVVGPEKEE------------SKPE----------EADQN-------------------------------------------------------EFVFIAFARVFSGTLKRGMELFNLSPKHDPRQPTHRKEG----------EAPYASRVTIGDLYMFMGGELQLLDEVPAGNIVGIGGLESHIVKTATLSSS-LDCTSFSELSVMATPILRVAIEPVQPQDMPKLVKGLKLLNQADACVQVSVAPTGEHVITTLGEVHVEKCVHDLEQSYAKIKVNVSKPIVSFRETIVPAATVDMVNEAIVKT----------AEDKDVSKKIAVQQ-------TLNKLGTLKVIAVPLPAEAVELLETHSEFFKELAAIPRNQLLSEKW-TALLASIKVKLIAALKDLQLFGLSTLSPEE-LVNRIWALGPRNCGTNILLNLSDYEQPDFWSSHAKSDTDIRSKTDPRKDFNSSLVNGFQITSVAGPLCEEPMQGVCFAVLEWSIQ-------------------SEGED----------------------------------LNSRGPFSGQVLTAAKEVCRQAFQNQPQRLVTPMYSCNIVVNAEMLGKMYAVIGRRHGKILSGDLTQGSGNFAVTCLLPVIESFNFAQEMRKQTSGLACPQLMFSHWEVIDIDPFWLPTTEEELMHFGEKADSANRAKVYMDSVRRRKGLFVDEQVVEHAEKQRTLSKNK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53893-1", "uniprot_id": "RIA1_YEAST", "id": "P53893-1", "name": "Ribosome assembly protein 1", "aln": "MPRVESETYKRLQNDPSCIRNICIVAHVDHGKTSLSDSLLASNGIISQRLAGKIRFLDARPDEQLRGITMESSAISLYFRVLRKQEGSDEPLVSEHLVNLIDSPGHIDFSSEVSAASRLCDGAVVLVDVVEGVCSQTVTVLRQCWTEKLKPILVLNKIDRLITELQLTPQEAYIHLSKVIEQVNSVIGSFFANERQLDDLFWREQLEK-----------NENAEYIEKDDSGIYFNPTDNNVIFASAIDGWGFNIGQLAKFYEQKLGAKRENLQKVLWGDFYMDPKTKKIINNKGLKGRSLKPLFTSLILENIWKIYQNIITSRDSEMVEKIAKTLNIKLLARDLRSKDDKQLLRTIMGQWLPVSTAVLLTVIEKLPSPLESQTDRLNTILVSESDTAAMDP----RLLKAMKTCDKE--GPVSAYVSKMLSIPREELPVESKRIASSDELMERSRKAREEALNAAKHAGMVENMAMMDLNDNSKNTSDLYKRAKDTVMTPEVGEQTKPKPSRNNDVFCVVSEPSSALDLEFEYEGEDDSDSQDNFGLDFVPTDIDPNDPLSSMFEYEEEDPLLESIKQISEDVNDEVDDIFDEKEECLVAFARIYSGTLRVGQEISVLGPKYDPK-----------------CPEEHIETAIITHLYLFMGKELVPLDVCPSGNIVGIRGLAGKVLKSGTLIEKGVQGVNLAGVNFHFTPIVRVAVEPANPVEMSKLVRGLKLLDQADPCVHTYVENTGEHILCTAGELHLERCLKDLTERFAGIEITHSEPAIPYRETFLSASDMNPP------------------QNSQLGRGVHELL---------LSQYKITFRTFPLSGKVTDFLSQHQNSIKNILKTSTSSMDPVIESTGSSFLDKKSLLVAFEEVINQEEKSRELLSGFKVKLAGFGPSRVGCNILLSQ-DNLLGSLFEGTPAA-----------FEYSDSIKNGFQLAVSEGPLANEPVQGMCVLVESVHKMSQDE---------------IESIE------------------------------DPRYQQHIVDLSGRLITSTRDAIHEAFLDWSPRIMWAIYSCDIQTSVDVLGKVYAVILQRHGKIISEEMKEGTPFFQIEAHVPVVEAFGLSEDIRKRTSGAAQPQLVFSGFECIDLDPFWVPTTEEELEELGDTADRENIARKHMNAIRRRKGLFIEEKVVENAEKQRTLKKN-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 318, "similar_positions": 359, "identity": "25.87%" }, { "cls_id": "homologset.agr.SGD:S000005111", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZZM2-1", "uniprot_id": "A0A8I5ZZM2_RAT", "id": "A0A8I5ZZM2-1", "name": "Cyclic AMP-dependent transcription factor ATF-7", "aln": "------------------MGDDRPFVCSAPGCGQRFTNEDHLAVHK----HKHEMTLKFGP-ARTDSVIIADQTPTPTRFLKNCEEVGLFNELASS--FEHEFKKASDDDEKKASSAAGPLDMSLPSTPDIKVKEEEPVEVDSSPPDSPASCPCSPPLKDKEVATKPVVISTPTPTIVRPGSLPLH----LGYDP---LHPTLPSPTS--VITQAPPSNRQIGSPTGSLPLVMHLANGQTMPMLP-----GPPVQMP-----------SVISLARPVSMVPNIPGIPGPPVNNSGS----ISPSGHPMPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQN--------------------------------QILIQHPD--------------------------------APSPAQPQVSPAQPTPSTG---GRRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSLEKKAEELTSQNIQLSNEVTLLR---------------------------NEVAQLKQLLLAHKDCPVTALQK--------------------------KTQGYLESPKESSE----PTGSPAPVIQHS--SATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIMTPQSQSAGR--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P17544-6", "uniprot_id": "ATF7_HUMAN", "id": "P17544-6", "name": "Cyclic AMP-dependent transcription factor ATF-7", "aln": "------------------MGDDRPFVCNAPGCGQRFTNEDHLAVHK----HKHEMTLKFGP-ARTDSVIIADQTPTPTRFLKNCEEVGLFNELASS--FEHEFKKAADEDEKKA--AAGPLDMSLPSTPDIKIKEEEPVEVDSSPPDSPASSPCSPPLKEKEVTPKPVLISTPTPTIVRPGSLPLH----LGYDP---LHPTLPSPTS--VITQAPPSNRQMGSPTGSLPLVMHLANGQTMPVLP-----GPPVQMP-----------SVISLARPVSMVPNIPGIPGPPVNSSGS----ISPSGHPIPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQS--------------------------------QILIQHPD--------------------------------APSPAQPQVSPAQPTPSTG---GRRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSLEKKAEELTSQNIQLSNEVTLLR---------------------------NEVAQLKQLLLAHKDCPVTALQK--------------------------KTQGYLESPKESSE----PTGSPAPVIQHS--SATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIMTPQSQSAGR--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R0S1-1", "uniprot_id": "ATF7_MOUSE", "id": "Q8R0S1-1", "name": "Cyclic AMP-dependent transcription factor ATF-7", "aln": "------------------MGDDRPFVCSAPGCGQRFTNEDHLAVHK----HKHEMTLKFGP-ARTDSVIIADQTPTPTRFLKNCEEVGLFNELASS--FEHEFKKASDDDEKKG--AAGPLDMSLPSTPDIKIKEEEPVEVDSSPPDSPASSPCSPPLKEKEVTTKPVVISTPTPTIVRPGSLPLH----LGYDP---LHPTLPSPTS--VITQAPPSNRQIGSPTGSLPLVMHLANGQTMPMLP-----GPPVQMP-----------SVISLARPVSMVPNIPGIPGPPVNNSGS----ISPSGHPMPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQN--------------------------------QILIQHPD--------------------------------APSPAQPQVSPAQPTPSTG---GRRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSLEKKAEELTSQNIQLSNEVTLLR---------------------------NEVAQLKQLLLAHKDCPVTALQK--------------------------KTQGYLGK------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16951-1", "uniprot_id": "ATF2_MOUSE", "id": "P16951-1", "name": "Cyclic AMP-dependent transcription factor ATF-2", "aln": "------------------MSDDKPFLCTAPGCGQRFTNEDHLAVHK----HKHEMTLKFGP-ARNDSVIVADQTPTPTRFLKNCEEVGLFNELASP--FENEFKKASEDDIKKM-----PLDLSPLATPIIRSKIEEPSVVETTHQDSPLPHPESTTSDEKEVP--LAQTAQPTSAIVRPASLQVPNVLLTSSDSSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPASITSSNVHVP-----------AAVPLVRPVTMVPSVPGIPGP-------------SSPQPVQSEAKMRLKAALTQQHPPVTNG-DTVKGHGSGLVRTQSEES--------------------------------RPQSLQQP--------------------------------ATSTTETPASPAHTTPQTQNTSGRRRRAANEDPDEKRRKFLERNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLR---------------------------NEVAQLKQLLLAHKDCPVTAMQK--------------------------KSGYHTADKDDSSEDLSVPSSPHTEAIQHS--SVST-SNGVSSTSKAEAVATSVLTQMADQSTEPAL---SQIVMAPPSQAQPSGS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15336-1", "uniprot_id": "ATF2_HUMAN", "id": "P15336-1", "name": "Cyclic AMP-dependent transcription factor ATF-2", "aln": "MKFKLHVNSARQYKDLWNMSDDKPFLCTAPGCGQRFTNEDHLAVHK----HKHEMTLKFGP-ARNDSVIVADQTPTPTRFLKNCEEVGLFNELASP--FENEFKKASEDDIKKM-----PLDLSPLATPIIRSKIEEPSVVETTHQDSPLPHPESTTSDEKEVP--LAQTAQPTSAIVRPASLQVPNVLLTSSDSSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPASITSSNVHVP-----------AAVPLVRPVTMVPSVPGIPGP-------------SSPQPVQSEAKMRLKAALTQQHPPVTNG-DTVKGHGSGLVRTQSEES--------------------------------RPQSLQQP--------------------------------ATSTTETPASPAHTTPQTQSTSGRRRRAANEDPDEKRRKFLERNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLR---------------------------NEVAQLKQLLLAHKDCPVTAMQK--------------------------KSGYHTADKDDSSEDISVPSSPHTEAIQHS--SVST-SNGVSSTSKAEAVATSVLTQMADQSTEPAL---SQIVMAPSSQSQPSGS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q00969-1", "uniprot_id": "ATF2_RAT", "id": "Q00969-1", "name": "Cyclic AMP-dependent transcription factor ATF-2", "aln": "------------------MSDDKPFLCTAPGCGQRFTNEDHLAVHK----HKHEMTLKFGP-ARNDSVIVADQTPTPTRFLKNCEEVGLFNELASP--FENEFKKASEDDIKKM-----PLDLSPLATPIIRSKIEEPSVVETTHQDSPLPHPESTTNDEKEIP--LAQTAQPTSAIVRPASLQVPNVLLTSSDSSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPASITSSNVHVP-----------AAVPLVRPVTMVPSVPGIPGP-------------SSPQPVQSEAKMRLKAALTQQHPPVTNG-DTVKGHGSGLVRAQSEES--------------------------------RPQSLQQP--------------------------------ATSTTETPASPAHTTPQTQNTSGRRRRAANEDPDEKRRKFLERNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLR---------------------------NEVAQLKQLLLAHKDCPVTAMQK--------------------------KSGYHTADKDDSSEDLSVPSSPHTEAIQHS--SVST-SNGVSSTSKTEAGATSVLTQMADQSTEPAL---SQIVMAPSSQAQPSGS------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02930-1", "uniprot_id": "CREB5_HUMAN", "id": "Q02930-1", "name": "Cyclic AMP-responsive element-binding protein 5", "aln": "---------MIYEESKMNLEQERPFVCSAPGCSQRFPTEDHLMIHR----HKHEMTLKFPS-IKTDN-MLSDQTPTPTRFLKNCEEVGLFSELDCS--LEHEFRKAQEEESSKR-------NISMHNA-----------------VGGAMTGPGTHQLSSARLP---------------------------NHDTNVVIQQAMPSPQSSSVITQAPSTNRQIGPVPGSLSSLLHLHNRQRQPMPASMPGTLPNPTMPGS-------SAVLMPMERQMSVNSSIMGMQGPNLSN-PC----ASPQVQPMHSEAKMRLKAALTHHPAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLHTGNQAQVSPATQQMQPTQTIQPPQPTGGRRRRVVDEDPDERRRKFLERNRAAATRCRQKRKVWVMSLEKKAEELTQTNMQLQNEVSMLK---------------------------NEVAQLKQLLLTHKDCPITAMQK--------------------------ESQGYLS-PESSPPASPVPACSQQQVIQHN--TITT------SSSVSEVVGSSTLSQLTTHRTDLNP------IL-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LPZ0-1", "uniprot_id": "A0ABK0LPZ0_RAT", "id": "A0ABK0LPZ0-1", "name": "Cyclic AMP-responsive element-binding protein 5", "aln": "---------MIYEESKMNLEQERPFVCSAPGCSQRFPTEDHLMIHR----HKHEMTLKFPS-IKTDN-MLSDQTPTPTRFLKNCEEVGLFSELDCS--FEHEFRKAQEEESSKR-------NISMHNT-----------------VGGTMTGPGAHQLGSSRMP---------------------------NHDTSVVIQQAMPSPQSSSVITQAPSTNRQIGPVPGSLSSLLHLHNRQRQPMPASMPGTLPNPTMPGS-------SAVLMPMERQMSVNSSIMGMQGPNLSN-PC----ASPQVQPMHSEAKMRLKAALTHHPAAMSNGNMSTIGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLHTGNQAQVSPATQQMQPTQTIQPPQPTGGRRRRVVDEDPDERRRKFLERNRAAATRCRQKRKVWVMSLEKKAEELTQTNMQLQNEVSMLK---------------------------NEVAQLKQLLLTHKDCPITAMQK--------------------------ESQGYLS-PESSPPASPVPACSQQQVIQHN--TITT------SSSVSEVVGSSTLSQLTSHRTDLNP------IL-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2PE13-1", "uniprot_id": "Q2PE13_DROME", "id": "Q2PE13-1", "name": "", "aln": "---------------MDTAGDMDHLASVSFGDFETKSPEGDVSCYQNFRAQTEHVSLDISLGQKSDTLFAADQTPTPTRLIKNCDEVGLFEDLQHVNPFDIGFQQAAERN-----------------------------------VSGTPSRPEARPNDGESLH-----------------------------------TPQVYPVEAPTVVSVPSENQVPQSVSCGDMDVDQLLATTVTSPSKAS-----QDGPPP-------------LQLIQPQVLTWVLPAQSVP--------------ISIATVDCNRNRVKPTGAIHPFILPKPTAKELNKTSKRPEPILVSC--------------------------------NPPNNEPS--------------------------------SASLTPTSQLPIKERLKAIIHSNNNRRSFSTPPKAAKAKDRSRDEDCMERRRAAASRYRNKMRNEHKDLIKQNAQLQQENQELH---------------------------ERISRLEKELQQHRSHSSLAGVV--------------------------ADQLRIP-----------PSSIHLLINVPN--VLVP-------SSASNASAAKK--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02100-1", "uniprot_id": "SKO1_YEAST", "id": "Q02100-1", "name": "CRE-binding bZIP protein SKO1", "aln": "---------MSSEERSRQPSTVSTFDLEPNPFEQSFASSKKALSLPG---TISHPSLPKELSRNNSTSTITQHSQRSTHSLNSIPEENGNSTVTDNS-NHNDVKKDSPSFLPGQ-------QRPTIISPPILTPGGSKRLPPLLLSPSILYQANSTTNPSQNSHSVSVSNSNPSAIGVSSTSGSLYPNSSSPSGTSLIRQPRNSNVTTSNSGNGFPTNDSQMPGFLLNLSKSGLTPNESNIRTGLTPGILTQSYNYPVLPSINKNTITGSKNVNKSVTVNGSIENHPHVNIMHPTVNGTPLTPGLSSLLNLPSTGVLANPVFKSTPTTNTTDGTVNNSISNSNFSPNTSTKAAVKMDN------PAEFNAIEHSAHNHKENENLTTQIENNDQFNNKTRKRKRRMSSTSSTSKASRKNSISRKNSAVTTAPAQKDDVENNKISNNVTLDENEEQERKRKEFLERNRVAASKFRKRKKEYIKKIENDLQFYESEYDDLTQVIGKLCGIIPSSSSNSQFNVNVSTPSSSSPPSTSLIALLESSISRSDYSSAMSVLSNMKQLICETNFYRRGGKNPRDDMDGQEDSFNKDTNVVKSENAGYPSVNSRPIILDKKYSLNSGANISKSNTTTNNVGNSAQNIINSCYSVTNPLVINANSDTHDTNKHDVLSTLPHNN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . . . . :* .... :::: .*: ::. * . . : . .:: . . : : . . .: : . * : : : : . . : . . : . . . . : . : .. . . : . .*:. . : * . : .:.:. : . :* . * . :: *:. : . : ", "identical_positions": 9, "similar_positions": 85, "identity": "1.34%" }, { "cls_id": "homologset.agr.SGD:S000005112", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYQ8-1", "uniprot_id": "FAHD1_RAT", "id": "Q6AYQ8-1", "name": "Oxaloacetate tautomerase FAHD1, mitochondrial", "aln": "MASTKP-LSRFWEWGKNIVCVGRNYADHVKEMRSTVLSEPVLFLKPSTAYAP----------------------EGS---PVLMPAYCRNLHHEVELGVLLGRRGEAVPEA---AAMDYVAGYALCLDMTARDVQDECKKKGLPWTLAKSFTSSCPVSAFVPKEKIPDPHA-----LRLWLKVNGELRQEGKTSSMIFSIPYIISYVSKIITLEEGDLILTGTPKGVGAVKENDEIEAGIDG----VVSMRFKVERSKY-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0F8-1", "uniprot_id": "FAHD1_MOUSE", "id": "Q8R0F8-1", "name": "Oxaloacetate tautomerase FAHD1, mitochondrial", "aln": "MASTKP-LSRFWEWGKNIVCVGRNYADHVKEMRSTVLSEPVLFLKPSTAYAP----------------------EGS---PVLMPAYCRNLHHEVELGVLLGKRGEAIPEA---AAMDYVAGYALCLDMTARDVQEECKKKGLPWTLAKSFTSSCPVSAFVPKEKIPDPHA-----LRLWLKVNGELRQEGKTSSMIFSIPYIISYVSKIITLEEGDLILTGTPKGVGPIKENDEIEAGIDG----VVSMRFKVKRSEY-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P587-4", "uniprot_id": "FAHD1_HUMAN", "id": "Q6P587-4", "name": "Oxaloacetate tautomerase FAHD1, mitochondrial", "aln": "MAASRP-LSRFWEWGKNIVCVGRNYADHVREMRSAVLSEPVLFLKPSTAYAP----------------------EGS---PILMPAYTRNLHHELELGVVMGKRCRAVPEA---AAMDYVGGYALCLDMTARDVQDECKKKGLPWTLAKSFTASCPVSAFVPKEKIPDPHK-----LKLWLKVNGELRQEGETSSMIFSIPYIISYVSKIITLEEGDIILTGTPKGVGPVKENDEIEAGIHG----LVSMTFKVEKPEY-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDE2-1", "uniprot_id": "Q9VDE2_DROME", "id": "Q9VDE2-1", "name": "oxaloacetate tautomerase", "aln": "MACQNQNAANFLSNGKKIVGVALNYMDVVLARNVPVPKEPLVFLKPTSSYLQ----------------------EGQ---PIVLPKVFTKVAYEVELGVVIGKPCKNVSKA---DAMSYVAGYCLALDLTAQCNLGPARAAGHPWTLGKGFDTSTPVSQFIPIEKVTDPHN-----LPLWLTVNGDLKQNGCTADLIFKVPDIISYVSKYMTLEANDLILTGTPNGADAFKAGDVIQCGMAD----LAKLTFQVEAE---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53889-1", "uniprot_id": "FMP41_YEAST", "id": "P53889-1", "name": "Oxaloacetate tautomerase FMP41, mitochondrial", "aln": "MS------YNYLKAARKIICIGRNYAAHIKELNNSTPKQPFFFLKPTSSIVTPLSSSLVKTTRPANSTFNGLNEDGTNPGPIFIPRG-VKVHHEIELALIVSKHLSNVTKMKPEEVYDSISGVALALDLTARNVQDEAKKKGLPWTISKGFDTFMPISAIVSREKFSSYKSNLQDIFRVKCSVNGQLRQDGGTNLMLHPLHKILQHISTMISLEPGDIILTGTPAGVGELKPGDRVHCELLQNNDNIVDMNFECENRPGPYEFRET", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .: . .::*: :. ** : . .. .:*..****::: :* *:.:* :: :*:**.:::.: :.: . . :.* .*.**:**: .: * ***:.*.* : *:* ::. **... : : : .***:*:*:* * ::. : *:.::*. ::** .*:****** *.. .* .* :.. : :..: *: : ", "identical_positions": 53, "similar_positions": 93, "identity": "19.92%" }, { "cls_id": "homologset.agr.SGD:S000005113", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAW2-1", "uniprot_id": "PISD_RAT", "id": "D3ZAW2-1", "name": "Phosphatidylserine decarboxylase proenzyme, mitochondrial", "aln": "MAVAGGRGCVRSLREG-----VLWRSSPCHCDYT--------ATRHFLGALQKLP--------LQAW---VRKVHTAPLR----TLFL-------------------------LRPVPILLAAG----GGYAGYRQYEKYRERQLEKLGLEIP--PKLASHWEVSLYKSVPTRLLSRACGRLNQVELPSWLRRPVYSLYIWTFGVNMTEAAVEDLQHYRNLSEFFRRKLKPQARPVCGLHSVIS-PSDGKILTFGQVK--NSEVEQVKGVTYSLESFLGPRACTEDLPFPP-ASSCDS---------------------------------------------------------FRNQLVTRE--GNELYHCVIYLAPGDYHCFHSPTDWTVSHRRHFPGSLMSVNPGMARWIKELFCHNERVVLTGDWKHGFFSLTAVGATNVGSIRIHFDQDLHTN--------SPSYSKGSYNDLSFVTHANKEGIPMRKGEPLGEFNLGSTIVLIFEAPKDFNFRLKAGQKILFGEALGSL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BSF4-1", "uniprot_id": "PISD_MOUSE", "id": "Q8BSF4-1", "name": "Phosphatidylserine decarboxylase proenzyme, mitochondrial", "aln": "MAASGGRACVRSLRGG-----VLWRSSPCHYEST--------ATRHFLGTLQKLP--------LQAG---VRNFHTAPVR----SLFL-------------------------LRPVPILLATG----GGYAGYRQYEKYRERKLEKLGLEIP--PKLASHWEVSLYKSVPTRLLSRACGRLNQVELPYWLRRPVYSLYIWTFGVNMTEAAVEDLHHYRNLSEFFRRKLKPQARPVCGLHCVTS-PSDGKILTFGQVK--NSEVEQVKGVTYSLESFLGPRANTEDLPFPP-ASSSDS---------------------------------------------------------FRNQLVTRE--GNELYHCVIYLAPGDYHCFHSPTDWTISHRRHFPGSLMSVNPGMARWIKELFCHNERVVLTGDWKHGFFSLTAVGATNVGSIRIHFDRDLHTN--------SPRYSKGSYNDLSFVTHANKEGIPMRKGEPLGEFNLGSTIVLIFEAPKDFNFRLKAGQKIRFGEALGSL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UG56-3", "uniprot_id": "PISD_HUMAN", "id": "Q9UG56-3", "name": "Phosphatidylserine decarboxylase proenzyme, mitochondrial", "aln": "MATSVGHRCLGLLHGV-----APWRSSLHPCEIT--------ALSQSLQPLRKLP--------FRAFRTDARKIHTAPAR----TMFL-------------------------LRPLPILLVTG----GGYAGYRQYEKYRERELEKLGLEIP--PKLAGHWEVALYKSVPTRLLSRAWGRLNQVELPHWLRRPVYSLYIWTFGVNMKEAAVEDLHHYRNLSEFFRRKLKPQARPVCGLHSVIS-PSDGRILNFGQVK--NCEVEQVKGVTYSLESFLGPRMCTEDLPFPP-AASCDS---------------------------------------------------------FKNQLVTRE--GNELYHCVIYLAPGDYHCFHSPTDWTVSHRRHFPGSLMSVNPGMARWIKELFCHNERVVLTGDWKHGFFSLTAVGATNVGSIRIYFDRDLHTN--------SPRHSKGSYNDFSFVTHTNREGVPMRKGEHLGEFNLGSTIVLIFEAPKDFNFQLKTGQKIRFGEALGSL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JJ26-1", "uniprot_id": "A0AC58JJ26_DANRE", "id": "A0AC58JJ26-1", "name": "Phosphatidylserine decarboxylase proenzyme, mitochondrial", "aln": "MKSIRKKQREHLLDHGK----DGWKKQICGCDQESSLPLGGVSVSVRTRTQKKLLPHISN---MAALVRRVLIAHLAATRN---TSFLQNGGCGIRWSQRRFFSKGFPGLQARVRPLTLLIATG----GGYVGYDQYGRYKDRQLEKLGIEVP--PHIANEVQVTIYKTIPTRLLSRAWGRLNRVDLPNWLRKPIYNLYIWTFGVNMKEAAVEDLQHYRNLGEFFRRKLKPQVRPVCDSHCVIS-PADGKILHFGRVK--NCEVEQVKGVTYSLETFLGPRTWSESLTANRNEDDPGT---------------------------------------------------------FQDALVTKE--GNELFHCVIYLAPGDYHCFHSPTDWRVAHRRHFPGALMSVNPGVARWIKELFCHNERVVLSGEWTHGFFSLTAVGATNVGSIRIYFDKELRTN--------NPRYNKGTYNDFSYVTNNNQEGISMRKGEHLGEFNLGSTIVLLFEAPRDFTFNLQAGQKIRFGEALGTM------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCE0-1", "uniprot_id": "Q9VCE0_DROME", "id": "Q9VCE0-1", "name": "Phosphatidylserine decarboxylase proenzyme, mitochondrial", "aln": "MVSYFVPRGRFLLKAGNLRQVVQQQHQPAQLQLQPIKGPQPQAQNASLPVARHLRQFSSNPASKEAPLHHRRPQHKQQPNP---SQELAQ-----------------------IRRNILSRWTGFLLRWAPMGICVFG-AIEWQLQKNRCEKEGKPRTASELQSRIYCSLPLRIISRCWGWLAACYLPPSLRPYVYGWYSNTFDVNLSEAMYPEYEHYNSLAEFFTRPLKEGVRVIDQQAPLVS-PADGKVLHFGSAS--DSLIEQVKGVSYSIEDFLGP------LETVEQANSGAS---------------------------------------------------------YAQALKKKSDGSTELYQCVIYLAPGDYHRFHSPTAWKPTIRRHFSGELLSVSPKVAGWLPGLFCLNERVLYMGQWKHGFFSYTAVGATNVGSVEIYMDADLKTNRWTGFNVGKHPPSTYEYDELVLNKELTEAPKEFGKGDLVGQFNMGSTIVLLFEAPKNFKFDIIAGQKIRVGESLGHIVGSK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39006-1", "uniprot_id": "PSD1_YEAST", "id": "P39006-1", "name": "Phosphatidylserine decarboxylase proenzyme 1, mitochondrial", "aln": "MSIMPVKNALAQGRTLLMGRMPAVKFSTRMQLRNRTAVLWNRKFSTRLFVQQRRS--------SGEIVDRAKAAAANSGRKQVSMK--------------------------WVVLTSFTIVLG----TILLVSRNDSTEEDATEGKKGRRTRKIKIFNNNWLFFCYSTLPLNAMSRLWGQVNSLTLPIWVRPWGYRLYSFLFGVNLDEMEDPDLTHYANLSEFFYRNIKPGTRPVAQGEDVIASPSDGKILQVGIINSETGEIEQVKGMTYSIKEFLGTHSHPLMSKSASSLDLTSDEEKHREFARVNRIQLAGSEDTEQPLLNFKNEGDQSVREFKPSVSKNIHLLSQLSLNYFSNGFSCSEPHDTELFFAVIYLAPGDYHHFHSPVDWVCKVRRHFPGDLFSVAPYFQRNFPNLFVLNERVALLGSWKYGFFSMTPVGATNVGSIKLNFDQEFVTNS----KSDKHLEPHTCYQAVYENASKILGGMPLVKGEEMGGFELGSTVVLCFEAPTEFKFDVRVGDKVKMGQKLGIIGKNDLK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . :: . : : * : * . .. * ::* . :** * : ** :* * * *.**: * : ** .*.*** * :* .* : : : *:**::* .* . :*****::**:: ***. : : : . ..**: .********** ****. * ****.* *:** * . : ** **** *.*.:**** *.********:.: :* :: ** . *: . : **: :* *::***:** **** :*.* : .*:*: .*: ** : ", "identical_positions": 112, "similar_positions": 79, "identity": "20.66%" }, { "cls_id": "homologset.agr.SGD:S000005116", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M801-1", "uniprot_id": "F1M801_RAT", "id": "F1M801-1", "name": "Anaphase-promoting complex subunit 1", "aln": "MSNFSEERATMIAAG---DLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVG---------------------------------SLQEVTIHEKQKESWQLRKGVSEIGDAADYDEELYVAGNMVIWSKGSKSQ-----ALAVYKAFTVDSTVQQALWCDFIISQ----DKSEKIYKSHELEKCICILQSSCMNMHSI-DGKDYIASLPFQVANVWATKYGLLFERSSSSHEVPPSLPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDPAVKIVFLNIDPSIVMTYDAVQNVHSVWTLRRVKPEEETAVLKFPEQAGTLQNAATSSSLTAHLRSLSKGESPVASPFQNYSSIHSQSRSASSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFNLSSHNQSPKRHSISHSPSGSFNDSFLAPETEPIVPELCIDHLWTETLP-NMREKNSQASKVFITTDLCGQKFLCFLVEAQLQLRCVKFQESNDKTQLIFGSVTNIHAKDAAPVEKIDTMLVLEGNGNLVLYTGVVRVGKVFIP------GLPAPSLTMSNMMPRPSTPLDGVSTPKPLSKLLGSMDEVVLLSPVPELRDSSKLNDSLYNEDCTFQQLGTYIH-------------------SVRDPVHNRVTLELSNGSMVRITIPEVATSELVQTCLQAIKFILPKEVAVQVLVKWYNVHSAPGGP--SCHSEWSLFVICLLNMMGYNTDRLAWTRSFDFEGSLSPVIAPKKARPSDTGSDDDWEYLLNSEYHHNVES----------HLLNKSLCLNALEVTKTKDEDFPQNLSLDSSTLLFAHIPAIFFVLHLVYEELKLNTLMGEGICSLIDLLVQLARDLKLEPYLDHYYRDYPTLVKTTGQVCTIDQGQMGFMHHPSFFTSEPPSIYQWVSSCLKGEG-TPPYPYLPGICERSRLVVLSIALYTLGDESCVSDETSQYLSKVTLTPQKPQAEQEENRFTFRQSASVSVLAERLVVWMASVGFTLRDLETLPFGIALPIRDAIYHCREQPDSDWSEAVCLLIGRQDLSKQACEGNLPR-----------------GKSVLSSDVASGAEAEEEDDGMNDLNHEVMS-LIWSEDLRVQDVRRLLQSAQPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMASWASFHNGVAAGLKIAP-ASQIDSAWIVYNKPK-HAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHVPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSD-------LNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLD--FVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRE---NSIS--LSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMNYLSAPNASVTGP----YNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTG---GEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALIEVTYKGTQWYEQTKEELMAPTLLPELHLLKQMKVKGPRYWELLIDLSKGEQHLRSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISSFTSDPALLSFAEYFCKPTVSMGQKQEILD--LFSSILYECVAQETPEMLPAYIAMDQALRSLKKRDMSNTSDLWQIKLILEFFSSRSHQERQQTYPKRGLFINSEFLPVVKCTVDSTLDQWLQAGGDVCVHAYLSGQPVEKSQLNMLACFLVYHSVPAPRHLPPLGLEGSTSFAELLFRFRHLKMPVRALLRLAPVLLGNPQPMVM--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53995-1", "uniprot_id": "APC1_MOUSE", "id": "P53995-1", "name": "Anaphase-promoting complex subunit 1", "aln": "MSNFSEERATMIAAG---DLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVG---------------------------------SLQEVTIHEKQKESWQLRKGVSEIGDAADYDEELYVAGNMVIWSKGSKSQ-----ALAVYKAFTVDSTVQQALWCDFIISQ----DKSEKIYKSHELEKCICILQSSCMNMHSI-DGKDYIASLPFQVANVWATKYGLLFERCSSSHEVPPSLPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDPAVKIVFLNIDPSIVMTYDAVQNVHSVWTLRRVKPEEENAVLKFPEQAGTLQNATTSSSLTAHLRSLSKGESPVASPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGAQRFNLSSHSQSPKRHSISHSPSGSFNDSFLAPETEPIVPELCIDHLWTETLP-NIREKNSQASKVFITTDLCGQKFLCFLVEAQLQLRCVKFQESNDKTQLIFGSVTNIHAKDAAPVEKIHTMLVLEGNGNLVLYTGVVRVGKVFIP------GLPAPSLTMSNMMPRPSTPLDGVGTPKPLSKLLGSMDEVVLLSPVPELRDSSKLNDSLYNEDCTFQQLGTYIH-------------------SVRDPVHNRVTLELSNGSMVRITIPEVATSELVQTCLQAIKFILPKEVAIQVLVKWYNVHSAPGGP--SCHSEWSLFVICLLNMMGYNTDRLAWTRSFDFEGSLSPVIAPKKARPSDTGSDEDWEYLLNSEYHRNVES----------HLLNKSLCLTALEVSNAKDEDFSQNLSLDSSTLLFAHIPAIFFVLHLVYEELKLNTLMGEGICSLIDLLVQLARDLKLDSYLDHYYRDSPTLVKTTGQVCTIDQGQMGFMHHPPFFTSEPPSIYQWVSSCLKGEG-MPPYPYLPGICERSRLVVLSIALYTLGDESCVSDETCQYLSKVTSTPQKPQAEQEENRFTFRHSASVSVLAERLVVWMASVGFTLRDLETLPFGIALPIRDAIYHCREQPDSDWSEAVCLLIGRQDLSKQACEGNLPR-----------------GKSVLSSEVSSGTEAEEEDDGMNDLNHEVMS-LIWSEDLRVQDVRRLLQSAQPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPVPKLNLTGRAPPRNTTVDLNSGNIDVPPNMASWASFHNGVAAGLKIAP-ASQIDSAWIVYNKPK-HAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHVPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSD-------LNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLD--FVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRE---NSIS--LSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFSCLHKFAKDFMNYLSAPNASVTGP----YNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTG---GEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALIEVTYKGTQWYEQTKEELMAPTLLPELHLLKQMKVKGPRYWELLIDLSKGEQHLRSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISSFTSDPALLSFAEYFCKPTVSMGPKQEILD--LFSSILYECVAQETPEMLPAYIAMDQALRSLKKRDMSDTSDLWQIKLILEFFSSRSHQDRQHTYPKRGLFINSEFLPVVKCTVDATLDQWLQAGGDVCVHAYLSGQPVEKSQLNMLACFLVYHSVPAPRHLPPMGLEGSTSFAELLYRFRHLKMPVRALLRLAPVLLGNPQPMVM--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1A4-1", "uniprot_id": "APC1_HUMAN", "id": "Q9H1A4-1", "name": "Anaphase-promoting complex subunit 1", "aln": "MSNFYEERTTMIAAR---DLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVG---------------------------------SLQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQ-----ALAVYKAFTVDSPVQQALWCDFIISQ----DKSEKAYSSNEVEKCICILQSSCINMHSI-EGKDYIASLPFQVANVWPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSSLTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETIT-NIREKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAAPVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIP------GLPAPSLTMSNTMPRPSTPLDGVSTPKPLSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIH-------------------SIRDPVHNRVTLELSNGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGP--SYHSEWNLFVTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVES----------HLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSEPPSIYQWVSSCLKGEG-MPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRITIAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPASDWPEAVCLLIGRQDLSKQACEGNLPK-----------------GKSVLSSDVPSGTETEEEDDGMNDMNHEVMS-LIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIAP-ASQIDSAWIVYNKPK-HAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSD-------LNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLD--FVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRE---NSIS--LSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASVTGP----HNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTG---GEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPALLSFAEYFCKPTVNMGQKQEILD--LFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMPVRALLRLAPLLLGNPQPMVM--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXV3-1", "uniprot_id": "Q9VXV3_DROME", "id": "Q9VXV3-1", "name": "", "aln": "MIAVAEPPLEFVPRGRQTSAEHPGPHDQPMARHQLPTTEHLLLQRLQNVNISSAGEDCPSGGQESWTVRELYDDYEASEERAALRRKLTERTKRCGLQATSLPNRLLNPPLVRRVEPMCDYMVNNEEELYVNRNTVVWTQGVNDDDDTDNGVYRRMCFTTDTPVRFACFLNRSFVRGRLAQLKAAVHPDDDHLTAICVMDQDALRVYCS-NGEDFLANLDFPVSQLWQTKYGLLLEKDSSNALISHMS--IPMPRLFSMSHPLHEACPVVLKT----ATGSTGYMTEPEYTVVFTTEESDLVMLYDAKFFKHFVARLRKVTPEEINYVSQQMELGQTLMGPRSMAGNSFSSTKQTGATPKATN--LSFAARNINTTTTGMGNQFGLSQSQSFSGVLGQSNRASLGTPLSQLQSSISQQSMSVKDMRKLTHVKP------------AKPIEPELCMEHIWTENIYGTQREFCEMATRAFIHTDLVGQTFLCYLLARSCRLQLVRLTGYGRGEVQLSTHASTLAAKDAVGLKRMHMIAVLDPSGSLLLYTGTVLISKVHITPFLAPTSIPTPLVTPMTAAPSPSASPAPSHVKTPMAAAGPASGIPSGSSSFVEVRRSSLLPTKAPGDVAAFEEELHMLSPIQPQPVSYTQRQAHNVCKSLRDPAGNRLTLVYATGRMLRIALPFLNDTRLLTRCVATLRQVLSPTQFLDFVIRWYSDRNPPGSRNYSIEQEWLLFRSTLLALMGLTAAPDVDAGENYARCATPPLHTQFGGGATATESSDGSSCSSNSTLGGQDEPKKRRIYNDCDDFTDDDWEFLLLQTTLAPCGADGHSYSVNIGALLFRMIPAIFFSLHLLYEDLKLDADFYGALPYLATFLHQLAIDMQLESYVLHYILDFPELSNRTGKLSLLGAEHGAMMLHQELLRVPAPSVFAQLEHIIVGEEEVMPYTFLECVNERSRILLQLVSLVTHG------HERLNYWWQLLEIPGAVQAN--FTRRSKRNITADAPRSHQMLQLLLAMRLTRRDIERFPAAVHLIVAEALEEARLSPPMGCSMATYELILRPELAAHAQLPFLETSTGQPHCGRVYKEDSLSARCPPTGGSETDSPAQLRRDDMDNMDTKLLR-LRFPDDMRVDEVRRLLNSSEPVVIEVQQAPGTSDHEFIEEQEKQLFALCSRTMTLPVGRGMFTLRTMLPRPSESLTMPKLCLLGKEPLKGTTIEMQ--QIEFPANMQMWPSFHNGVATGLKISPQAQDIDSNWIVYNKPKTHSHNALEHAGFLMALGLNGHLKTLSFMSVYKYLVKCDEMTNVGLLLGISAAHRGTMDTKTTKLLSVHLEALLPATAMELDIPQSTQVAAIMGVGLLYQGSAKRHIAEVLLQEIGRPPGPEMENSIERESYAMTAGLSLGLVTLGQGESPAGLRD-------LQLPDTLHYYMVGGVKRPIGGSQKEKYRLASFQVREGDTVNIDVTAPGATLALGLMFFNSGNAAIAEWMQPPDSRYLLD--MVRPDFLLLRTISRGLILWQDVRPDNAWFQAQFPRALRA---HLKLPFYENEYAPEDYDVDYEAISQAYCNIMAGAAFCIGLKYAGTENLVAFATLRSVIKDFLRFPSRPMGECAGR----TTVESCLMVLLISISLVFAGSGNCEILRIIRFLRSRVGPQYPHITYGSHMAIHMSLGLLFLGAGRFTISQTPESIAALVCAFFPKFPIHSNDNRYHLQALRHLYVLAVEPRLFLPRDIDTNKLCLANISVLEVG---ATELRRLPIAPCILPVLSTLQQVVVDDENYWPVCFERSRNWDQLEKALEMSAPIDIKKRTGCLSHLEDPDRLKSMLAQTLTMEQSICWQIDMNDLQQFASERMVKQFLSRCLDTKGTDLSPPELMKRHQVMLLFYNAVVKDRMHFLPVYLTLYDHVT----KSMPNNIDVWQMKLIDAYLS-RSQESEHPLISVELIQMMQELFKQEMEDSTRELCLPLREFLSRRRLDPSYVTTVSGPDLQRAFCVINYYNLLPNMLNGVDLSTGTVNYMRLLYEFRRLNLGAHTIFGLMKILQSLATEVVTLDEAALLAYTMGDQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53886-1", "uniprot_id": "APC1_YEAST", "id": "P53886-1", "name": "Anaphase-promoting complex subunit 1", "aln": "------------------------------MTSKPSTRNDYLPRETHNGEYTGDS----------------------------------------------------PEWQLQINITNKIGGINGDIWLSRDGRSVKWCIEDQCLR----------QFTYNQKIIKAGYIDFEKTP-----------------DCFVVVLSDIAHVYMLKNGGSTTVCFPFQIGNAFWYANGVILERETSASFMDGGY--DLKPIEFDLKHKYITLTDPMAPFGLISITNTFKGGINSASGNKTDILQDFQLVLFPSDKDKCIAVFLDRNSKVLRFYYSRILSSDQSRKGELTISSTKKTGLDAAGNSQKSGGISKDLRKFSHLTRRSTSINSNSHDFNAAERVLSGNVGNASGRTDIFALPSSCSRRSLSATLDRMGNNIAP------------TNRAAPSGFFDSSSANTAT------HSNITPVSQPMQQQQQEYLNQTATSSKDIVLTEISSLKLPDDIIFTSRR----LSSILSKLKFLSLRFERREGLLIFHEPTHFCKIWLIDLLP-DVLDSIPFKIYGNSPQNMIRLENLKLKEPSRIQAMYIHELLESCLILVSEG----QNKEEYKACLYDPFVKITS--------------------PSKNISEELTKQNSLPSLQKLFP--YPETSFTKLCFEAVKYITSPAFNISFIFLWQSAYS------------------ILLSRANDDVVGGLKMEHDAFSLVLSLLILPIPSSSAQEYQEYKEIYERDLFQHLKQDS-----------------------------------------EITSSVLPRIVIGLHLIREEYSLNVLCRNEHALLGQFLRFATAAMGWPDLWQSYY--VPKMDSESKTFLHPREQNSTFFHPLDEPPSITKSLYSITENSSIPLCPFISFSRLVATDTQVELRITPRSFKILGLYELVHSPNFLPDYVLGILSSFKVDKDELQTYPLGILVPLQNILKILEDKLSEVRDNLELLDRADLQRCSAIINSIRSDSKEVLKRGQRDSYMLCKVPLAKNRSSLSKKPSD----IYSILSEIVKSASQVPLDGSAMRMSNIQDDEDIDEGRSLKLNAGLIFSEDKRFTHVVSLLAYYRPTKTQFFTT-KTEYAQILAQKKYFAKIMALRTCTNGVGWGAVAYATEKPISTQKWVIQPLNLISVFP--DDTKITVKAPEDIAHDIVEWGQFHAGVSSGLRISKKATGITGSWIAFNKPK---ELDAYHGGFLLGLGLNGHLKNLEEWHIYNYLSPRNTHISIGLLLGMSSSMKGSMDSKLIKVISVHLVAFLPSGSSDLNIDLKLQTAGIIGMGMLYLNSRHKRMSDSIFAQLVSLLNVNDEMVAD-EEYRLAAGISLGLINLGAGQTKLRKWDSSLLGLGDDLPEDVYDSSDVEQNVMYEDLTTKLLEIVTSTYDVENDWIPENSQIGAVIAIMFLFLKSNNFGISNMLKVDLKEILKANINTRPELLMYREWASNMILWEFIGDDLSFIMKDVDIGVKFSELN--------------------TDLLPIYYTMAGRILAMGIRFASTGNLKIRNILLSLVDKFLPLYQYPGKQNLDFRLTISVINVLTNVIVVSLSMVMCASGDLEVLRRVKYLHEVASGPYSDLFQEIPSSKSDVSGVTQVTSNTNTPGNSDRERVDETAASLDDERSSNGSD-------------ISDPTAYLEDKKDIDDHYGKFISTNLALGFLFLGSGQYALNTSTLESIAFLSMSVLP---TYTTPHPLQELKHFWSMAVEPRCLVIKDISTGDAVNN---VPIELVVEEDVEKEEVIREISTPCLLPDFSKIKSIRVKMHGYFPLEVNFTKDYSASDFFSGGTIIYIQRKSESVFENKASFRNVEDIHVALKRKAAESKNYSRLNLKNEQGNTTSSQLVESLGIQDLTMVELDTLLSAGNNTALTDSESYNLG--------LLCSDKNSGDILDCQLELWYKSFGPHDE-----------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * : : . . :: . : : * . * * : ** : : * : : .: :: .. .:: :* . . : * :.: : *:::*: :* : * *.: * : :. : : :: : : . * : . : . : . : :. . . : . . : : . . . . : .. .: . . . * . . * * :: *. :: ::. . : . : * :* . : ..: : .: : :: .*::: . . *: : : : .. * * . . . . . . :: . :.:* : : :: : : *. ::: : . :..:. * . . *: . . . : . .: .. : : :. : :* *.: ***: *: .*:. * :* : : * * : : . : :: . *:: . .:. * : .: : :: * : . : . .. . : : : . . :: : ::: . * :: .: . : : * :. . :: * :.:* *. .* ** .*. :. . ::: ::: :. ** : ** * .: : * .:: : * * . * . * :.. :: * .** **::**:*: * * . **.:**** . :.***:.*******..* ::.** . .:*****:*:: *:** . :::*:*: *:**. : :*:: . *.*.::*:*::* .: ::: :: :: :: . : * : *.* ::**::**:: ** *.. * ::*: :: . . : . : : : : **.:*: ::::::.* .*:: :: . * .:*::*: * : :***: : : :. :. :: : : . :** :.:*:::*.: ** * .. ..*: . * . . :: *:::*:::*:..**: ::*: ::*: .. .: : *: : .. : . : . . .* . . .: :* : . * : :.. . : . * : *. : : .. . :. : . :* : :: : : .: : *:. : . . . ::* .: . : : : :. .:. : :::* . * : : : : . . :: : * .. . ", "identical_positions": 164, "similar_positions": 495, "identity": "7.86%" }, { "cls_id": "homologset.agr.SGD:S000005119", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6URK4-1", "uniprot_id": "ROA3_RAT", "id": "Q6URK4-1", "name": "Heterogeneous nuclear ribonucleoprotein A3", "aln": "-----------------------------------------------------------------------------------------------------------------MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLR-------------------KLFIGGLSFETTDDSLREHFEKWG-----------------TLTDCVVMRDPQTKRSRGFGFVTYSCVEE--VDAAMCARPHKVDGRVVEPKRAVSR---EDSVKP---------GAHLTVKKIFVGGIKEDTE-EYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHD-TVDKIVVQKYHTINGHNCEVKKALSKQEMQSAGS-QRGRGGG---------SGNFMG-RGGNFG--------GGGGNFGRGGNFG-GRGGYGGGGGGS--------------RGSYGGG---DGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDGYNEGGNFG-----GGNYGGG----GNYNDFGNYSGQQQSNYGPMKGGSFGG--------RSSGSPYGGG------------YGSGGGSGGYGS-RRF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG05-1", "uniprot_id": "ROA3_MOUSE", "id": "Q8BG05-1", "name": "Heterogeneous nuclear ribonucleoprotein A3", "aln": "-----------------------------------------------------------------------------------------------------------------MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLR-------------------KLFIGGLSFETTDDSLREHFEKWG-----------------TLTDCVVMRDPQTKRSRGFGFVTYSCVEE--VDAAMCARPHKVDGRVVEPKRAVSR---EDSVKP---------GAHLTVKKIFVGGIKEDTE-EYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHD-TVDKIVVQKYHTINGHNCEVKKALSKQEMQSAGS-QRGRGGG---------SGNFMG-RGGNFG--------GGGGNFGRGGNFG-GRGGYGGGGGGS--------------RGSYGGG---DGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDGYNEGGNFG-----GGNYGGG----GNYNDFGNYSGQQQSNYGPMKGGSFGG--------RSSGSPYGGG------------YGSGGGSGGYGS-RRF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51991-1", "uniprot_id": "ROA3_HUMAN", "id": "P51991-1", "name": "Heterogeneous nuclear ribonucleoprotein A3", "aln": "-----------------------------------------------------------------------------------------------------------------MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLR-------------------KLFIGGLSFETTDDSLREHFEKWG-----------------TLTDCVVMRDPQTKRSRGFGFVTYSCVEE--VDAAMCARPHKVDGRVVEPKRAVSR---EDSVKP---------GAHLTVKKIFVGGIKEDTE-EYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHD-TVDKIVVQKYHTINGHNCEVKKALSKQEMQSAGS-QRGRGGG---------SGNFMG-RGGNFG--------GGGGNFGRGGNFG-GRGGYGGGGGGS--------------RGSYGGG---DGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGG-YDGYNEGGNFG-----GGNYGGG----GNYNDFGNYSGQQQSNYGPMKGGSFGG--------RSSGSPYGGG------------YGSGGGSGGYGS-RRF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49312-1", "uniprot_id": "ROA1_MOUSE", "id": "P49312-1", "name": "Heterogeneous nuclear ribonucleoprotein A1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------MSKSESPKEPEQLR-------------------KLFIGGLSFETTDESLRSHFEQWG-----------------TLTDCVVMRDPNTKRSRGFGFVTYATVEE--VDAAMNARPHKVDGRVVEPKRAVSR---EDSQRP---------GAHLTVKKIFVGGIKEDTE-EHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHD-SVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSG----------SGNFGGGRGGGFG--------GND-NFGRGGNFS-GRGGFGGSRGG----------------GGYGGS---GDGYNGFGNDG----------------------------------------------------SNFGGG----GSYNDFGNYN-NQSSNFGPMKGGNFGG--------RSSG-PYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09651-1", "uniprot_id": "ROA1_HUMAN", "id": "P09651-1", "name": "Heterogeneous nuclear ribonucleoprotein A1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------MSKSESPKEPEQLR-------------------KLFIGGLSFETTDESLRSHFEQWG-----------------TLTDCVVMRDPNTKRSRGFGFVTYATVEE--VDAAMNARPHKVDGRVVEPKRAVSR---EDSQRP---------GAHLTVKKIFVGGIKEDTE-EHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHD-SVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSG----------SGNFGGGRGGGFG--------GND-NFGRGGNFS-GRGGFGGSRGG----------------GGYGGS---GDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGGGSGSNFGGG----GSYNDFGNYN-NQSSNFGPMKGGNFGG--------RSSG-PYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04256-1", "uniprot_id": "ROA1_RAT", "id": "P04256-1", "name": "Heterogeneous nuclear ribonucleoprotein A1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------MSKSESPKEPEQLR-------------------KLFIGGLSFETTDESLRSHFEQWG-----------------TLTDCVVMRDPNTKRSRGFGFVTYATVEE--VDAAMNARPHKVDGRVVEPKRAVSR---EDSQRP---------GAHLTVKKIFVGGIKEDTE-EHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHD-SVDKIVIQKYHTVNGHNCEVRKALCKQEMASASSSQRGRSG----------SGNFGGGRGGGFG--------GND-NFGRGGNFS-GRGGFGGSRGG----------------GGYGGS---GDGYNGFGNDG----------------------------------------------------SNFGGG----GSYNDFGNYN-NQSSNFGPMKGGNFGG--------RSSG-PYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q32P51-1", "uniprot_id": "RA1L2_HUMAN", "id": "Q32P51-1", "name": "Heterogeneous nuclear ribonucleoprotein A1-like 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------MSKSASPKEPEQLR-------------------KLFIGGLSFETTDESLRSHFEQWG-----------------TLTDCVVMRDPNTKRSRGFGFVTYATVEE--VDAAMNTTPHKVDGRVVEPKRAVSR---EDSQRP---------GAHLTVKKIFVGGIKEDTE-EHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHD-SVDKIVIQKYHTVKGHNCEVRKALPKQEMASASSSQRGRRG----------SGNFGGGRGDGFG--------GND-NFGRGGNFS-GRGGFGGSCGG----------------GGYGGS---GDGYNGFGNDG----------------------------------------------------SNFGGG----GSYNDFGNYN-NQSSNFGPMKGGNFGG--------RSSG-PYGGGGQYFAKPQNQGGYGVSSSSSSYGSGRRF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GJN1-1", "uniprot_id": "A0A8I6GJN1_RAT", "id": "A0A8I6GJN1-1", "name": "Heterogeneous nuclear ribonucleoprotein A1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------LSQSPPRNRTEQLW-------------------KLFIDGLSFETTDESLRSHFERWG-----------------TLTDCVVMRDPNTKRPRGFGFVTYTTVEE--VDAAMNARPHKVDGRVVEPKRAVSR---EDSQRP---------GAHLTVKKIFVGSIKEDTE-EHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHD-SVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRNG----------SGNFGG-RGGGFG--------GND-NFGRGGNFS-GRGGFGGSRGG----------------GGYGGS---GDGYNGFGNDG----------------------------------------------------SNFGGG----GSYNDFGNYN-NQSSNFGPMKGGNFGS--------RSSG-SYGGGGQYFANPRNQGGYGGSSSSSSYGSGRRF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A7VJC2-1", "uniprot_id": "ROA2_RAT", "id": "A7VJC2-1", "name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "aln": "-------------------------------------------------------------------------------------------------------------------------------MEKTLETVPLERKKREKEQFR-------------------KLFIGGLSFETTEESLRNYYEQWG-----------------KLTDCVVMRDPASKRSRGFGFVTFSSMAE--VDAAMAARPHSIDGRVVEPKRAVAR---EESGKP---------GAHVTVKKLFVGGIKEDTE-EHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHD-PVDKIFLQKYHTINGHNAEVRKALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFR--------GGSDGYGSGRGFGDGYNGYGGGPGG----------------GNFGGSPGYGGGRGGYGGGG-------------------PGYGNQGGGYGGG-------------------YDNYGGGNYGSGNYNDFGNYN-QQPSNYGPMKSGNFGGS-------RNMGGPYGGG---------NYGPGGSGGSGGYGGRSRY-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22626-1", "uniprot_id": "ROA2_HUMAN", "id": "P22626-1", "name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "aln": "-------------------------------------------------------------------------------------------------------------------------------MEKTLETVPLERKKREKEQFR-------------------KLFIGGLSFETTEESLRNYYEQWG-----------------KLTDCVVMRDPASKRSRGFGFVTFSSMAE--VDAAMAARPHSIDGRVVEPKRAVAR---EESGKP---------GAHVTVKKLFVGGIKEDTE-EHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHD-PVDKIVLQKYHTINGHNAEVRKALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFR--------GGSDGYGSGRGFGDGYNGYGGGPGG----------------GNFGGSPGYGGGRGGYGGGG-------------------PGYGNQGGGYGGG-------------------YDNYGGGNYGSGNYNDFGNYN-QQPSNYGPMKSGNFGGS-------RNMGGPYGGG---------NYGPGGSGGSGGYGGRSRY-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88569-1", "uniprot_id": "ROA2_MOUSE", "id": "O88569-1", "name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "aln": "-------------------------------------------------------------------------------------------------------------------------------MEKTLETVPLERKKREKEQFR-------------------KLFIGGLSFETTEESLRNYYEQWG-----------------KLTDCVVMRDPASKRSRGFGFVTFSSMAE--VDAAMAARPHSIDGRVVEPKRAVAR---EESGKP---------GAHVTVKKLFVGGIKEDTE-EHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHD-PVDKIVLQKYHTINGHNAEVRKALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFR--------GGSDGYGSGRGFGDGYNGYGGGPGG----------------GNFGGSPGYGGGRGGYGGGG-------------------PGYGNQGGGYGGG-------------------YDNYGGGNYGSGSYNDFGNYN-QQPSNYGPMKSGNFGGS-------RNMGGPYGGG---------NYGPGGSGGSGGYGGRSRY-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13151-1", "uniprot_id": "ROA0_HUMAN", "id": "Q13151-1", "name": "Heterogeneous nuclear ribonucleoprotein A0", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MENSQLC-------------------KLFIGGLNVQTSESGLRGHFEAFG-----------------TLTDCVVVVNPQTKRSRCFGFVTYSNVEE--ADAAMAASPHAVDGNTVELKRAVSR---EDSARP---------GAHAKVKKLFVGGLKGDVA-EGDLIEHFSQFGTVEKAEIIADKQSGKKRGFGFVYFQNHD-AADKAAVVKFHPIQGHRVEVKKAVPKEDIYSGGGGGGSRSS----------RGGRGG-RGRGGG------RDQNGLSKGGGGGYN-SYGGYGGGGGGG--------------YNAYGGG----GGGSSYGGSD------------------------------------------------------YGNG------FGGFGSYS-QHQSSYGPMKSGGGGGGGGSSWGGRSNSGPYRGG------------YGGGGG---YGGSSF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LU98-1", "uniprot_id": "A0ABK0LU98_RAT", "id": "A0ABK0LU98-1", "name": "Heterogeneous nuclear ribonucleoprotein A0", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MENSQLC-------------------KLFIGGLNVQTSESGLRGHFEAFG-----------------TLTDCVVVVNPQTKRSRCFGFVTYSNVEE--ADAAMAASPHAVDGNTVELKRAVSR---EDSARP---------GAHAKVKKLFVGGLKGDVA-EGDLIEHFSQFGAVEKAEIIADKQSGKKRGFGFVYFQSHD-AADKAAVVKFHPIQGHRVEVKKAVPKEDIHAGGG--GARAA----------RGGRGGGRGRGGGGGGGGGRDQNGLAKGGGGGYN-SYGGYGG-------------------YGAYGGG----GGGGSYGGSD------------------------------------------------------YGNG------FGGFGSYS-QHQSSYGPMKSGGGGGGGGGSWGGRSNSGPYRGG------------YGGGGGGG-YGGGSF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JII5-1", "uniprot_id": "DAZP1_MOUSE", "id": "Q9JII5-1", "name": "DAZ-associated protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MNSAGADEIG-------------------KLFVGGLDWSTTQETLRSYFSQYG-----------------EVVDCVIMKDKTTNQSRGFGFVKFKDPNC--VGTVLASRPHTLDGRNIDPKPCTPRGMQPERTRPKEGWQKGPRSDSSKSNKIFVGGIPHNCG-ETELREYFKKFGVVTEVVMIYDAEKQRPRGFGFITFEDEQ-SVDQAVNMHFHDIMGKKVEVKRAEPRDSKNQAPGQPGASQWG----------SRVAPSAANGWAGQPPPTWQQGYGPQGMWVPAGQAIGGYGPPPAGRGAPPPPPPFTSYIVSTPPGGFPPPQGFPQGYGAPPQFSFGYGPPPPPPDQFAPPGVPPPPATPGAAPLAFP---------------PPPSQAAPDMSKPPTAQPDFPYGQYG-YGQDLSGFGQGFSDPSQQPPSYGGPSVPGSGGPPAGGSGFGRGQNHNVQGFHPYRR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EP5-1", "uniprot_id": "DAZP1_HUMAN", "id": "Q96EP5-1", "name": "DAZ-associated protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MNNSGADEIG-------------------KLFVGGLDWSTTQETLRSYFSQYG-----------------EVVDCVIMKDKTTNQSRGFGFVKFKDPNC--VGTVLASRPHTLDGRNIDPKPCTPRGMQPERTRPKEGWQKGPRSDNSKSNKIFVGGIPHNCG-ETELREYFKKFGVVTEVVMIYDAEKQRPRGFGFITFEDEQ-SVDQAVNMHFHDIMGKKVEVKRAEPRDSKSQAPGQPGASQWG----------SRVVPNAANGWAGQPPPTWQQGYGPQGMWVPAGQAIGGYGPPPAGRGAPPPPPPFTSYIVSTPPGGFPPPQGFPQGYGAPPQFSFGYGPPPPPPDQFAPPGVPPPPATPGAAPLAFP---------------PPPSQAAPDMSKPPTAQPDFPYGQYAGYGQDLSGFGQGFSDPSQQPPSYGGPSVPGSGGPPAGGSGFGRGQNHNVQGFHPYRR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JJ54-1", "uniprot_id": "HNRPD_RAT", "id": "Q9JJ54-1", "name": "Heterogeneous nuclear ribonucleoprotein D0", "aln": "---------------------------------------------------MSEEQFGGDGAAAAATAAVG------------------GSAGEQEGAMVAAA-QGAAAAAGSGSGGG--SAPGGTEGGSTEAEGAKIDASKNEEDEGHSNSSPRHTEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKFG-----------------DVVDCTLKLDPITGRSRGFGFVLFKESES--VDKVMDQKEHKLNGKVIDPKRAKAMKT------------------KEPVKKIFVGGLSPDTP-EEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEE-PVKKIMEKKYHNVGLSKCEIKVAMSKEQY--QQQQQWGSRGGF--------AGR---ARGR---------------GGGPSQNWNQGYSNYWNQGYGS----------------YG---YNSQGYG-GYGGYD------------------------------------------------------YTGYNS-YYGYG----DYSNQQSGYGKVS------------------------------------RRGG-HQNSYKPY----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60668-1", "uniprot_id": "HNRPD_MOUSE", "id": "Q60668-1", "name": "Heterogeneous nuclear ribonucleoprotein D0", "aln": "---------------------------------------------------MSEEQFGGDGAAAAATAAVG------------------GSAGEQEGAMVAAAAQGPAAAAGSGSGGGG-SAAGGTEGGSAEAEGAKIDASKNEEDEGHSNSSPRHTEAAAAQREEWKMFIGGLSWDTTKKDLKDYFSKFG-----------------EVVDCTLKLDPITGRSRGFGFVLFKESES--VDKVMDQKEHKLNGKVIDPKRAKAMKT------------------KEPVKKIFVGGLSPDTP-EEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEE-PVKKIMEKKYHNVGLSKCEIKVAMSKEQY--QQQQQWGSRGGF--------AGR---ARGR---------------GGGPSQNWNQGYSNYWNQGYGN----------------YG---YNSQGYG-GYGGYD------------------------------------------------------YTGYNN-YYGYG----DYSNQQSGYGKVS------------------------------------RRGG-HQNSYKPY----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14103-1", "uniprot_id": "HNRPD_HUMAN", "id": "Q14103-1", "name": "Heterogeneous nuclear ribonucleoprotein D0", "aln": "---------------------------------------------------MSEEQFGGDGAAAAATAAVG------------------GSAGEQEGAMVAAT-QGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKFG-----------------EVVDCTLKLDPITGRSRGFGFVLFKESES--VDKVMDQKEHKLNGKVIDPKRAKAMKT------------------KEPVKKIFVGGLSPDTP-EEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEE-PVKKIMEKKYHNVGLSKCEIKVAMSKEQY--QQQQQWGSRGGF--------AGR---ARGR---------------GGGPSQNWNQGYSNYWNQGYGN----------------YG---YNSQGYG-GYGGYD------------------------------------------------------YTGYNN-YYGYG----DYSNQQSGYGKVS------------------------------------RRGG-HQNSYKPY----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99729-1", "uniprot_id": "ROAA_HUMAN", "id": "Q99729-1", "name": "Heterogeneous nuclear ribonucleoprotein A/B", "aln": "---------------------------------------------------MS------EAGEEQPMETTG------------------ATENGHEAVPEASRGRGWTGAA-AGAGGATAAPPSGNQNG---AEGDQINASKNEEDAG-------------------KMFVGGLSWDTSKKDLKDYFTKFG-----------------EVVDCTIKMDPNTGRSRGFGFILFKDAAS--VEKVLDQKEHRLDGRVIDPKKAMAMK-------------------KDPVKKIFVGGLNPESPTEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEE-PVKKVLEKKFHTVSGSKCEIKVAQPKEVY--QQQQ-YGS-GGR--------GNR---NRGNRGSG-------GGGGGGGQSQSWNQGYGNYWNQGYG-----------------------YQQGYGPGYGGYD------------------------------------------------------YSPYG--YYGYGP-GYDYSQGSTNYGKSQ------------------------------------RRGG-HQNNYKPY----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O14979-1", "uniprot_id": "HNRDL_HUMAN", "id": "O14979-1", "name": "Heterogeneous nuclear ribonucleoprotein D-like", "aln": "MEVPPRLSHVPPPLFPSAPATLASRSLSHWRPRPPRQLAPLLPSLAPSSARQGARRAQRHVTAQQPSRLAGGAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRTARQHPPADSSVTMEDMNEYSNIEEFAEGSKINASKNQQDDG-------------------KMFIGGLSWDTSKKDLTEYLSRFG-----------------EVVDCTIKTDPVTGRSRGFGFVLFKDAAS--VDKVLELKEHKLDGKLIDPKRAKALKG------------------KEPPKKVFVGGLSPDTS-EEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEE-PVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAA--------AGGRGGTRGR---------------GRGQGQNWNQGFNNYYDQGYGN----------------YNSAYGGDQNYS-GYGGYD------------------------------------------------------YTGYNYGNYGYGQGYADYSGQQSTYGKAS------------------------------------RGGGNHQNNYQPY----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z130-1", "uniprot_id": "HNRDL_MOUSE", "id": "Q9Z130-1", "name": "Heterogeneous nuclear ribonucleoprotein D-like", "aln": "-----------------------------------------------------------------------------------------------------------------------MEDMNEYSNIEEFAEGSKINASKNQQDDG-------------------KMFIGGLSWDTSKKDLTEYLSRFG-----------------EVVDCTIKTDPVTGRSRGFGFVLFKDAAS--VDKVLELKEHKLDGKLIDPKRAKALKG------------------KEPPKKVFVGGLSPDTS-EEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEE-PVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAA--------AGGRGGARGR---------------GRGQGQNWNQGFNNYYDQGYGN----------------YNSAYGGDQNYS-GYGGYD------------------------------------------------------YTGYNYGNYGYGQGYADYSGQQSTYGKAS------------------------------------RGGGNHQNNYQPY----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3SWU3-1", "uniprot_id": "HNRDL_RAT", "id": "Q3SWU3-1", "name": "Heterogeneous nuclear ribonucleoprotein D-like", "aln": "-------------------------------------------------------------------------------------------MTGTARSALPLPQS-PARALRPSGAARAAPSLSPSR----FS-ACPLDPSSFPTSGN-------------------KMFIGGLSWDTSKKDLTEYLSRFG-----------------EVVDCTIKTDPVTGRSRGFGFVLFKDAAS--VDKVLELKEHKLDGKLIDPKRAKALKG------------------KEPPKKVFVGGLSPDTS-EEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEE-PVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAA--------AGGRGGARGR---------------GRGQGQNWNQGFNNYYDQGYGN----------------YNSAYG-DESYS-GYGGYD------------------------------------------------------YTGYNYGSYGYGQGYTDYSGQQSTYGKAS------------------------------------RGGGNHQNNYQPY----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53883-1", "uniprot_id": "NOP13_YEAST", "id": "P53883-1", "name": "Nucleolar protein 13", "aln": "------------------------MSETELSKEDAVTKKDNEEQVKKALLDPTKKRKAEDEIEIDLKSSIPLSKKQKRLLRRGKVTLEELNAKYNIDPKSIEEYKEDAEKKKSGASEKDAQGEESTINTPTGDESGEVVKKKKKDENK------------------YGVWIGNLSFDTTKDDLVRFFIAKTKDNEDEKSRVTEQDITRLSMPRVAAKNSNAMKNKGFCYMFFKNVEQ--MKAVLELSESHLNGRNMLIKDSENYSGRPDKDDLVAMS------KNPPSRILFVGNLSFDVT-DDLLRKHFQHCGDIVKIRMATFEDSGKCKGFAFIDFKNEEGSTNALKDKSCRKIAGRPLRMEYGEDRSKRQVRKKVENVSRNN----------------------------------SSSFDISNNKGYDRAGQDNGSK------------------------PEYKRSNANRR----------------------------------------------------------------PPVDSNNRTKSSVALATAQ------------------------------------RGSAAIVPSQGKKVKFD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W108-1", "uniprot_id": "Q9W108_DROME", "id": "Q9W108-1", "name": "RRM domain-containing protein", "aln": "----------------------------------------------------------------------------------------------------------------------MASDSGSDYEVEAFFNPKRVQRTVNDDSAD---------------------LLGNFDDQKRREIFEGTYVDKE--------------------DGRNPSDPEDSKSEDEAKSDDEAAAEGSAASGAEEEESAENGQITSDQLSSLLRG----------------ASKTNRHVLYVTNLNFETT-KDDLELHFSAAGTVKSIRIP----KKRRGGFAFVEMADLS-SFQNAFQLHNTELQGRNIKVQISEAGKKKSANKKNIIKQKNR----------------------------------KLAEMRNEQKTFTKSGK------------------------------FYDKDLKKEK---------------------------------------------------------------AKEMLARKRWRKKPAPRPT------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q86U06-1", "uniprot_id": "RBM23_HUMAN", "id": "Q86U06-1", "name": "Probable RNA-binding protein 23", "aln": "-MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSKKKRSRSHNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVG-----------------KVRDVRIISDRNSRRSKGIAYVEFCEIQS--VPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANN------LQKGNGGPMRLYVGSLHFNIT-EDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDLG------------------------------SAGGRFQLMAKLAEGAGIQLPST-----------------AAAAAAAAAQAAALQLNG----------------------------------------------------------------AVPLGALNPAALTALSPALN---------------------------------LASQCFQLSSLFTPQTM--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . * : . ::* .: : . : * * : : . *: *: . . . : .: . ", "identical_positions": 6, "similar_positions": 26, "identity": "0.98%" }, { "cls_id": "homologset.agr.SGD:S000005121", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C2C0-1", "uniprot_id": "RM22_RAT", "id": "P0C2C0-1", "name": "Large ribosomal subunit protein uL22m", "aln": "-------------MAAALLRELGALWVPN--------------------------------------------------------LRIWTTQMLR----------VLPQSCIHTSTSLDIS-----------RRWEKKNKIVYPPQLPG----------EPRRPAEIYHCRRQIKYSKDKMWYLAKLIRGMSIDQALAQLEFNDKKGAQIIKEVLLEAQDMAVRDHNVEFRSNLHIAESTSGR-GQCLKRIRYHGRGRFGIMEKVYCHYFVKLVEGPPPRP--EAPRTAVDHAKEYIQQLRSRTIIHTL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BU88-1", "uniprot_id": "RM22_MOUSE", "id": "Q8BU88-1", "name": "Large ribosomal subunit protein uL22m", "aln": "-------------MAAALLRELGALRVPN--------------------------------------------------------LRIWATQTLR----------VLPPSCIHTSASLDIS-----------RKWEKKNKIVYPPQLPG----------EPRRPAEIYHCRRQIKYSKDKMWYLAKMIRGMSIDQALAQLEFNDKKGAQIIKEVLLEAQDMAVRDHNVEFRSNLHIAESTSGR-GQCLKRIRYHGRGRFGIMEKVYCHYFVKLVEGPPPPP--EVPKTAVDHAKDYIQQLRSRTIIHTL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NWU5-1", "uniprot_id": "RM22_HUMAN", "id": "Q9NWU5-1", "name": "Large ribosomal subunit protein uL22m", "aln": "-------------MAAAVLGQLGALWIHN--------------------------------------------------------LRSRGKLALG----------VLPQSYIHTSASLDIS-----------RKWEKKNKIVYPPQLPG----------EPRRPAEIYHCRRQIKYSKDKMWYLAKLIRGMSIDQALAQLEFNDKKGAKIIKEVLLEAQDMAVRDHNVEFRSNLYIAESTSGR-GQCLKRIRYHGRGRFGIMEKVYCHYFVKLVEGPPPPP--EPPKTAVAHAKEYIQQLRSRTIVHTL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXB5-1", "uniprot_id": "RM22_DROME", "id": "Q9VXB5-1", "name": "Large ribosomal subunit protein uL22m", "aln": "--------------MHKVIRQMSQLRLQAPQGAA--------------------------------------------------LLRSADSSSISPAISPVSPP-ALQSKSLHTAASAGMLCAKWNKYNYGPRKWLEYNKTVHPPQETD----------EEPRNAYVCHMRSNIKYSPDKMWYIAAFVRGMSVDEALKQLNFVLKKGATDVKETILEAQQIAVERHNVEYKSNLWIAESFVGK-GRVFKGVRRHARGRFGKVEYKHCHYFVRLEEGEPPQHYYQEPQTPEQQYESWMEQMRSRKIINSL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53881-1", "uniprot_id": "RM22_YEAST", "id": "P53881-1", "name": "Large ribosomal subunit protein uL22m", "aln": "MNFHTARISQVGVISRALLSSVSRRWIHVTPISLNNSGGSLFGSITENKPKEGKNRGDEDAGSFSNRLAIASDSSGEAPEVNRDSITIENDKLLQQHIISLQQPEQLASQSLLSPLKREIYEANCKIN----GGFYKKDTIVKLPNSSERYKLKLTKREIEVLEPSVYAQSYRIKSSMKKATLLLRLLGGLDVMKAISQCHFSNKKIAREVAELLQKGVKDGQKLG--LKPEDLYISQIWTGSDGFWRKRVEFKARTRIGIISHPYIHVRCILRTKSVTKRRLAYEAHLKEQKRAPWVQLGDKPIRGVTGGVYKW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .:. : : : * . : :. . : : : :. * *: . . : .** * .* : :: *:.: :*: * .* ** * : * : :. . . . .:* *:: * * * :. :.* *:* :. : * * . : . *: .: * ", "identical_positions": 27, "similar_positions": 58, "identity": "8.57%" }, { "cls_id": "homologset.agr.SGD:S000005122", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62909-1", "uniprot_id": "RS3_RAT", "id": "P62909-1", "name": "Small ribosomal subunit protein uS3", "aln": "--MAVQISKKRKFVADGIFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVLGEKGRRIRELTAVVQKRFGFPEGSVELYAEKVATRGLCAIAQAESLRYKLLGGLAVRRACYGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPVNYYVDTAVRHVLLRQGVLGIKVKIMLPWDP-SGKIGPKKPLPDHVSIVEPKDEILPTTPISEQKGGKPEPPAMPQPVPTA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62908-1", "uniprot_id": "RS3_MOUSE", "id": "P62908-1", "name": "Small ribosomal subunit protein uS3", "aln": "--MAVQISKKRKFVADGIFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVLGEKGRRIRELTAVVQKRFGFPEGSVELYAEKVATRGLCAIAQAESLRYKLLGGLAVRRACYGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPVNYYVDTAVRHVLLRQGVLGIKVKIMLPWDP-SGKIGPKKPLPDHVSIVEPKDEILPTTPISEQKGGKPEPPAMPQPVPTA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23396-1", "uniprot_id": "RS3_HUMAN", "id": "P23396-1", "name": "Small ribosomal subunit protein uS3", "aln": "--MAVQISKKRKFVADGIFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVLGEKGRRIRELTAVVQKRFGFPEGSVELYAEKVATRGLCAIAQAESLRYKLLGGLAVRRACYGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPVNYYVDTAVRHVLLRQGVLGIKVKIMLPWDP-TGKIGPKKPLPDHVSIVEPKDEILPTTPISEQKGGKPEPPAMPQPVPTA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q06559-1", "uniprot_id": "RS3_DROME", "id": "Q06559-1", "name": "Small ribosomal subunit protein uS3", "aln": "MNANLPISKKRKFVSDGIFKAELNEFLTRELAEDGYSGVEVRVTPSRTEIIIMATKTQQVLGEKGRRIRELTAMVQKRFNFETGRIELYAEKVAARGLCAIAQAESLRYKLTGGLAVRRACYGVLRYIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPCNDYVETATRHVLLRQGVLGIKVKVMLPYDP-KNKIGPKKPLPDNVSVVEPKEEKIYETPETEYKIPPPSKPLDDLSEAKVL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05750-1", "uniprot_id": "RS3_YEAST", "id": "P05750-1", "name": "Small ribosomal subunit protein uS3", "aln": "--MVALISKKRKLVADGVFYAELNEFFTRELAEEGYSGVEVRVTPTKTEVIIRATRTQDVLGENGRRINELTLLVQKRFKYAPGTIVLYAERVQDRGLSAVAQAESMKFKLLNGLAIRRAAYGVVRYVMESGAKGCEVVVSGKLRAARAKAMKFADGFLIHSGQPVNDFIDTATRHVLMRQGVLGIKVKIMR--DPAKSRTGP-KALPDAVTIIEPKEEEPILAPSVKDYRPAEETEAQAEPVEA--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******:*:**:* ******:******:***********::**:** **:**:****:****.*** :***** : * : ****:* ***.*:*****:::** .***:***.***:*::*****************. ***:***.**::****:* * :::**.****:**********:* ** ..: ** *.*** *:::***:* :* : . . ", "identical_positions": 146, "similar_positions": 51, "identity": "59.11%" }, { "cls_id": "homologset.agr.SGD:S000005124", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7L0Q8-1", "uniprot_id": "RHOU_HUMAN", "id": "Q7L0Q8-1", "name": "Rho-related GTP-binding protein RhoU", "aln": "MPPQQGDPAFPDRCEAPPVPPRRERGGRGGRGPGEPGGRGRAGGAEGRGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSV------------------------------DGRPVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHC-----------PKAPIILVGTQSDLREDVKVLIELDK-CKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQYSDTQQQP------------------------------------------------------KKSKSRTPDKMKNLSKS-----------------------WWKKYCCFV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96L33-1", "uniprot_id": "RHOV_HUMAN", "id": "Q96L33-1", "name": "Rho-related GTP-binding protein RhoV", "aln": "MPPRELSEAEPPPLRAPTPPPRRRS------APPELG------------IKCVLVGDGAVGKSSLIVSYTCNGYPARYRPTALDTFSVQVLV------------------------------DGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIRTHN-----------PQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRACCYLECSALTQKNLKEVFDSAILSAIEHKARLEKK------------------------------------------------------LNAKG-----VRTLSRC-----------------------RWKKFFCFV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53879-1", "uniprot_id": "RHO5_YEAST", "id": "P53879-1", "name": "GTP-binding protein RHO5", "aln": "MRS----------------------------------------------IKCVIIGDGAVGKTSLLISYTTNSFPTDYVPTVFDNYSTTIAIPNGTASSPLELDNGNDKRGSLSSASSSPSTDRKLYKINLWDTAGQEDYDRLRPLCYPQTDIFLICFSVSEHASFANVTEKWLPELKQTSNIEGTSLYTKLGKYPILLVGTKSDLRDDPATQKKLQE-ANSDYVSQEEIDELVQRCGFMGYTECSAATQAGVREVFEQAVRYAIYEPESPNQKSANHTLTDELTTATTNTNGDKNIREQKQQPHHNNSTDSTLPKGSLQQEKEALNIKPTKKGQKDKIHEQSKSKGSKIASNNHHNKQAKPKTRNDKKKKKSKCVIL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . :***::*******:**::*** *.:*: * **.:*.:*. : : * :::* *****:::*:**.***.:**:** **** . :** *::***:**:: : *::****::***:* . :*:: .. *.: . .:. * **** ** .::***: *: .* :: :* :: *:. ** *.: ", "identical_positions": 80, "similar_positions": 68, "identity": "21.16%" }, { "cls_id": "homologset.agr.SGD:S000005125", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ERI6-1", "uniprot_id": "RDH14_MOUSE", "id": "Q9ERI6-1", "name": "Retinol dehydrogenase 14", "aln": "-------MAVASVAAALLAALGGALWLAARRFSGPRNQRQ-------QGGG--DPGLMHGKTVLITGAN-SGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRQELCQAGGAGPD---GTDGQLVVKELDLASLRSVRAFCQELLQEEP--RLDVLINNAG--------VFHCPYTKT-EDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSR---IVVVSSKLYKYGEINFED-LNSEQSYNKSFCYSRS-----KLANILFTRELARRLEG----------TNVTVNVLHPGIVRTNLGR-------HIHIPLLARPLFNLVSWAFFKTPLEGAQTSIYLACSPDVEGVSG-----RYFGDCKEEELLPKAMD-ESVARKLWDISEVMVGILK-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZUY0-1", "uniprot_id": "D3ZUY0_RAT", "id": "D3ZUY0-1", "name": "Retinol dehydrogenase 14", "aln": "-------MAVASVAAALLAALGGALWLAARRFSGSSGQRR-------QGGG--DPGLMHGKTVLITGAN-SGLGRATAGELLRLGARVIMGCRDRARAEEAAGQLRQELGQAGGLGPD---ATDGQLVVKELDLASLRSVRAFCQELLQEEP--RLDVLINNAG--------VFQCPYTKT-EDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSR---IVVVSSKLYKYGDINFED-LNSEQSYNKSFCYSRS-----KLANILFTRELAHRLEG----------TNVTVNVLHPGIVRTNLGR-------HIHIPLLARPLFNLVSWAFFKTPLEGAQTSIYLASSPDVEGVSG-----RYFGDCKEEELLPKAMD-ESVARKLWDISEVMVGILK-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HBH5-1", "uniprot_id": "RDH14_HUMAN", "id": "Q9HBH5-1", "name": "Retinol dehydrogenase 14", "aln": "-------MAVA-TAAAVLAALGGALWLAARRFVGPRVQRL-------RRGG--DPGLMHGKTVLITGAN-SGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPGVSGVGELIVRELDLASLRSVRAFCQEMLQEEP--RLDVLINNAG--------IFQCPYMKT-EDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSR---IVVVSSKLYKYGDINFDD-LNSEQSYNKSFCYSRS-----KLANILFTRELARRLEG----------TNVTVNVLHPGIVRTNLGR-------HIHIPLLVKPLFNLVSWAFFKTPVEGAQTSIYLASSPEVEGVSG-----RYFGDCKEEELLPKAMD-ESVARKLWDISEVMVGLLK-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VE80-1", "uniprot_id": "Q9VE80_DROME", "id": "Q9VE80-1", "name": "", "aln": "MGFIFGWLSTEHYVRDIFLMTS-VAAIVATLMSIRFYLRI-------TAGRCFTETKMEGKTVIITGAN-SGIGKETAKDLAGRGARIIMACRNLETANAVKDEIVKETKNN-------------KILVKKLDLGSQKSVREFAADIVKTEP--KIDVLIHNAG--------MALAFRGQTSEDGVELTMATNHYGPFLLTHLLIDVLKKSAPAR---IVIVASELYRLSSVNLAK-LNPIGTFPAAYLYYVS-----KFANIYFARELAKRLEG----------TKVTVNFLHPGMIDSGIWR-------NVPFPLNLP--MMAITKGFFKTTKAGAQTTIYLATSNEVANVSG-----KYFMDCKEATLNAAALD-EEKGLKIWEESVKIVKLTPQDPKI------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53878-1", "uniprot_id": "PBR1_YEAST", "id": "P53878-1", "name": "Uncharacterized oxidoreductase YNL181W", "aln": "-------MPLNIIGTALLDGTDKIPYYQTIKKVAPYVLATGAIKYWSRGPSNTWERKLHGKVYLVTGATSQGMGTSVAYKMAELGAQLIILTREVDEWVTEWCEELREKTKN------------ELIFVEKCDLSNLWEIRKFATSWLDNSPPRRLDGVIVMSGDMEPWGIPKISLPQRRSSKDGLELQIATNYVAIFHLLNLLQPSFKAQPPDRDVRIILATCWLQVVGDINIEDPLWQNAKYKSALKFFASSKLQLGLSMMELQRRLTEDIKNQKTNGAERTGKNVTITMVQPGTMRSNSLRRVISNGSVVLLIILYCILLYPILWLFTKSGRRGDQSFLYALMTPELEEVNLKDTKVKYISDCSIVKFARKEFDDEELQKKLFDNTERDILQLEKKVAAKRNANKTGNQNSKKKSQNKSRKDD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :: . : :.**. ::***. .*:* .* .: **::*: *: : :* : :.*.: **.. .:* *. . :. .* ::* :* :* :: :**.*: :..*: . * * :** :* ..* * *::.:. * ..:*: . * .: : : * :: : : *.*:. ::. .:**:..::** : :. * : : : : : * *: * *: :* : :: *. :*: **. : :* *. *::: : : ", "identical_positions": 57, "similar_positions": 112, "identity": "13.38%" }, { "cls_id": "homologset.agr.SGD:S000005126", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q499N3-1", "uniprot_id": "WDR18_RAT", "id": "Q499N3-1", "name": "WD repeat-containing protein 18", "aln": "MAAPMEVVVCTDSAAPLWSCMVWELHSGANLLTYRGG-QAGPRGLALLNGEYLLAAQQGKNYICAWELQR--KDQLQ-QKIMCPGPVTCLTTAPNG-------------------LYVLAGIAES--IYLWEVSTGNLLVILSR-HYQDVSCLKFTGDGSHFVSAGKDCLVLAWSLCSVLQADPS----RILAPRHVWSQHTLPITDLHCG------FGGPMARVATASLDQTMKLWAIS-------------------SGDLLLSVLFDMGITSVTMDLAEHYIFCGGSDGSIFQVDLCSRPGPREQSFQPEQNTGKVFKG---------------------------------HRNQVTCLSVSTDGSILLSGSHDESVRLWDVKSKQCVRTVPLKGP-----------VTNAAITLAPPSMLNPEFRPSLPLPHFNKHLLG--------AEHGDEAQGGGLRLQLGLHLQGKEPSYLERLEQLQAALSGYLEKN--------------------------------------------MLGSQ-MLPVRVFELEEEVRSLRKINRDLFDFSTRIITRPSK-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4VBE8-1", "uniprot_id": "WDR18_MOUSE", "id": "Q4VBE8-1", "name": "WD repeat-containing protein 18", "aln": "MAAPMEVVVCTDAAAQLWSCVVWELHSGANLLTYRGG-QAGPRGLALLNGEYLLAAQQGKNYICAWELQR--KDQLQ-QKIMCPGPVTCLTTAPNG-------------------LYVLAGIAES--IYLWEVCTGNLLVILSR-HYQDVSCLKFTGDGSHFVSAGKDCLALAWSLCSVLQADPS----RILAPRHVWSQHTLPITDLHCG------FGGPMARVATASLDQTVKLWAIS-------------------SGDLLLSVLFDMGITSVTMDLAEHHIFCGGSDGSIFQVDLCSWPGLREHSFQPEQNTGKVFKG---------------------------------HRNQVTCLSVSTDGSVLLSGSHDESVRLWDVKSKQCLRTVTLKGP-----------VTNAAIILAPPSMLNPEFRPSLPLPHFNKHLLG--------AEHGDEAQGGGLRLQLGLHLQGKEPSYLERLEQLQAVLSSYLEKN--------------------------------------------MLGSQ-MLPARVFDLEDEVRSLRKINRDLFDFSTRIITRPSK-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BV38-1", "uniprot_id": "WDR18_HUMAN", "id": "Q9BV38-1", "name": "WD repeat-containing protein 18", "aln": "MAAPMEVAVCTDSAAPMWSCIVWELHSGANLLTYRGG-QAGPRGLALLNGEYLLAAQLGKNYISAWELQR--KDQLQ-QKIMCPGPVTCLTASPNG-------------------LYVLAGVAES--IHLWEVSTGNLLVILSR-HYQDVSCLQFTGDSSHFISGGKDCLVLVWSLCSVLQADPS----RIPAPRHVWSHHALPITDLHCG------FGGPLARVATSSLDQTVKLWEVS-------------------SGELLLSVLFDVSIMAVTMDLAEHHMFCGGSEGSIFQVDLFTWPGQRERSFHPEQDAGKVFKG---------------------------------HRNQVTCLSVSTDGSVLLSGSHDETVRLWDVQSKQCIRTVALKGP-----------VTNAAILLAPVSMLSSDFRPSLPLPHFNKHLLG--------AEHGDEPRHGGLTLRLGLHQQGSEPSYLDRTEQLQAVLCSTMEKS--------------------------------------------VLGGQDQLRVRVTELEDEVRNLRKINRDLFDFSTRFITRPAK-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q68EI0-1", "uniprot_id": "WDR18_DANRE", "id": "Q68EI0-1", "name": "WD repeat-containing protein 18", "aln": "MSAPVEVVLSADSAGQLFNCAVYDPHTGSEFLSYRGG-NTSSRSLTILNGEYILGAQLGKNYINVWEIQR--KDQLQ-QKIVCPGIVTCLCASPDG-------------------LYVLAGIAEA--IYLWEVSTGNLLAILSR-HFQDLSCIKFTDDSSHFVSGGKDNLAFIWNLSSVVQLDSS----RTPEPRHILSRHSLPITDIHCG------LMGPQARVATASLDQTVKVWEIS-------------------SGEMLLSVLFDVGIMSVTFDPCEYFLFCGGSDGNIFQVSLCSTSLSRDKTFQSDSEGNQVFKG---------------------------------HRNLVTCLSVSMDGTVLLSGSNDETVRMWDVQSKQCIWTINHRGP-----------VTNAAIIPAPANMFLSDSHPAVPLPRFSRHLNP--------SEQGDGTGTGGMSLRLGANTQEPEGTYLEKAEELYSLMCAVTDKS--------------------------------------------VFGDGENTKVRVSELEEEVRTLKKINKDLYEFSTQLLTKPN------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W550-1", "uniprot_id": "Q9W550_DROME", "id": "Q9W550-1", "name": "WD repeat-containing protein 18", "aln": "MEDAVEALFISTSSEDNTTCSVQDLRTGTDLMRYKGGGCAQHHSLNMIHLNYVMAANSAKPLLHVWPINK--QEQMAGLRFVVPGKVNALALTPDG-------------------NFLVAGIQEN--IYLWHMSSGRMLNTLSK-HYQAITCLRFTDNGEHFISGGKDGAVLVWDLTFSAAPLDTGGGKDSTEPLYSFNDHGLAVTDLYSG------IGGIRSYLYTVSLDRCCKVYDLC-------------------GGVLLLSVVFPVALHSVIVSKMETRVYVGSSDGKVFVFNMENAPRMKEYHLEGEEIQAFVGHT---------------------------------YGKAITCLALNISATTLVSGGEDNQVCVWDVGSRQLIKSLSQKGS-----------VTNLHIRLLSPAIFLPEHKQPQMFADSLKRMISPW-DENDCIELFDPDYSGGRKTPELDYTQSHPGTDEEIILKLIASMSSGKNEDDEGIEAETKATDVEDSEVEEEEPESEPMETASKEAESEKSYAEYQPDSAQTSDERVQELQAENARLKAQSMRLFQIAFKYITSDTNGQAEITEKTKRKKARKT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53877-1", "uniprot_id": "IPI3_YEAST", "id": "P53877-1", "name": "Pre-rRNA-processing protein IPI3", "aln": "--MDEQVIFTTNTSGTIASVHSFEQIN------LRQCSTQSRNSCVQVGNKYLFIAQAQKALINVYNLSGSFKRESVEQRLPLPEILKCLEVVENDGVQYDRIQGVNHNLPDFNLPYLLLGSTESGKLYIWELNSGILLNVKPMAHYQSITKIKSILNGKYIITSGNDSRVIIWQTVDLVSASND-----DPKPLCILHDHTLPVTDFQVSSSQGKFLSCTDTKLFTVSQDATIRCYDLSLIGSKKKQKANENDVSIGKTPVLLATFTTPYSIKSIVLDPADRACYIGTAEGCFSLNLFYKLKGNAIVNLLQSAGVNTVQKGRVFSLVQRNSLTGGENEDLDALYAMGQLVCENVLNSNVSCLEISMDGTLLLIGDTEGKVSIAEIYSKQIIRTIQTLTTSQDSVGEVTNLLTNPYRLERGNLLFEGESKGKQPSNNNGHNFMKIPNLQRVIFDGKNKGHLHDIWYQIGEPEAETDPNLALPLNDFNAYLEQVKTQESIFSHIGKVSSNVKVIDN--------------------KIDATSSLDSNAAKDEEITELKTNIEALTHAYKELRDMHEKLYEEHQQMLDKQ------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . : :: . : . : .. : :*:: *: * : .: :. : : :: * :..* :. ::: * * :::*.: :* :* . *:* :: :: :..::::.*:* .: *. * * *.:**: . : : : * * * : : :. :* :. .: :: .. : : * ::* . : . : . * : . ::** :. ..: *: *. : * : :: *:* : :: . :** :: : : :.: : : . . .: : : :. .. .: :*: : * * :: : ", "identical_positions": 39, "similar_positions": 136, "identity": "6.5%" }, { "cls_id": "homologset.agr.SGD:S000005129", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIE3-1", "uniprot_id": "RM11_RAT", "id": "Q5XIE3-1", "name": "Large ribosomal subunit protein uL11m", "aln": "----MSKLSRVTRTLKKPEAGGVIRSIVRAGQAIPGPPLGPILGQRGVSINQFCKEFNEKTKDIKEGIPLPTKIFIKPDRTFELKIGQPTISYFLKAAAGIEKG------------ARQTG-KEVAGLVSLKHVYEIARVKAKDEAFAMQDVPLSSIVRSIIGSARSLGIRVVKDLSVDELAAFQKERAVFLAAQKRRIWQLRQKLPKSDPNLLHSEVRD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQF0-1", "uniprot_id": "RM11_MOUSE", "id": "Q9CQF0-1", "name": "Large ribosomal subunit protein uL11m", "aln": "----MSKLSRATRTLKKPEAGGVIRSIVRAGQAIPGPPLGPILGQRGVSINQFCKEFNEKTKDIKEGIPLPTKIFIKPDRTFELKIGQPTVSYFLKAAAGIEKG------------ARHTG-KEVAGLVSLKHVYEIACVKAKDDAFAMQDVPLSSVVRSIIGSARSLGIRVVKDLSAEELEAFQKERAVFLAAQKEADLAAQAEAAKK-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3B7-1", "uniprot_id": "RM11_HUMAN", "id": "Q9Y3B7-1", "name": "Large ribosomal subunit protein uL11m", "aln": "----MSKLGRAARGLRKPEVGGVIRAIVRAGLAMPGPPLGPVLGQRGVSINQFCKEFNERTKDIKEGIPLPTKILVKPDRTFEIKIGQPTVSYFLKAAAGIEKG------------ARQTG-KEVAGLVTLKHVYEIARIKAQDEAFALQDVPLSSVVRSIIGSARSLGIRVVKDLSSEELAAFQKERAIFLAAQKEADLAAQEEAAKK-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53875-1", "uniprot_id": "RM19_YEAST", "id": "P53875-1", "name": "Large ribosomal subunit protein uL11m", "aln": "-------MSQAAKNV-------IVKLIVGAGQAAPSPPVGPALGSKGIKAIDFCKEFNARSANYQPGVPVPVLITIKPDRTFTFEMKSPPTGYLLLKALKMDKGHGQPNVGTMLGSAPAKGPTRALGELSLKHVYEIAKIKKSDERHSLLEM--EGIVKSIVGVAKSMGIKVVP----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VFJ2-1", "uniprot_id": "RM11_DROME", "id": "Q9VFJ2-1", "name": "Large ribosomal subunit protein uL11m", "aln": "MSKAAGKLKSLKKTVERVTHTSKLKTNIPAGMAAAGPPLGPMLGQRAINIAAFCKDFNAKTAEMKEGVPLPCRISVNSDRSYDLAIHHPPATFFLKQAAGIQRG------------TMTPG-KEVAGMITLKHLYEIAAIKIQDPPNVLLTM--QQMCEMLISIARTCGIKVVREIDPAAYGEFLEERKLIVEQQRRELQEKREAKMLRTG---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :: : ** * ..**:** **.:.:. ***:** :: : : *:*:* * ::.**:: : : *. ::* * :::* : * ... * ::***:**** :* .* : : . : . ::. *:: **:** ", "identical_positions": 40, "similar_positions": 54, "identity": "18.18%" }, { "cls_id": "homologset.agr.SGD:S000005130", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZLQ8-1", "uniprot_id": "D3ZLQ8_RAT", "id": "D3ZLQ8-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "----------MGDARDICPHLDSIGEVTKEDLLLKSKGTCQSCGVAGPNLWACLQVTCPYVGCGESFADHSSIHAQVKRHNLTVNLTTLRVWCYACEREVFLEQRLAVHLPSSS---------------ARLSEQD--SPPPCHPLKAVPIAVADEGESESEDDDLKPRGLTGMKNLGNSCYMNAALQALSNCPPLTQFFLECGGLVRTD------------KKPALCKSYQKLISEVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLMDQLHEELKEPMVAAVAALTDARDSDSSDTDERRDGDRSPSEDEFLSCDSSSDRGEGDGQGRGGGSSKAEMELLISDEAGRAISEKERMKDRKFSWGQQRTNSEQVDEDADVDTAMAS-LDEQSREAQPPSP----RPTSPCQTPEPDNEVHIRS-----SSRPCSPVHHH-EGHTKLSSSPPRASPVRMGPS----YVLKKAQVPSTGGRRRKEQSYRSVISDVFNGSVLS-------LVQCLTCDRVSTTVETFQDLSLPIP----GKEDLAKLHSAIYQNVPAKPGACGDSYSSQGWLAFIVEYIRRFVVSCTPSWFWG----PVVTLEDCLAAFFAADELKGDNMYS------------------------CERCKKLRNGVKYCKVLCLP--------------------------------EILCVHLKRFRHEVMYSFKVSSHVSFPLEGLDLRPFLAKECTSQVTTYDLLSVICHHGTAGSGHYIAYCQNVIN-----------------------------------------------------------------------------------------------------GQWYEFDDQYVTEVHETVVQNVEAYVLFYRK------------------------------------------------------------------------------SSEEAMRERQQVVSLAAMQEPSLLRFYVSREWLNKFNTFAEPGPITNHTFLCPHGGIPPNKYHYIDDLVVILPQSVWEHLYSRFGGGPAVNHLYVCSICQVEIEA--------------------------------------------------------------------------------------------------------------------------------------------------------------------LAKRRRVEIDTFIKLNKAFQAEESPGVIYCISMHWFREWEAFVKGKDSEPPGPIDNSRIAQVKGSGHIQLKQGADYGQISEETWTYLNSLYGGGPEIAIRQSVAQLPDPESLHGEQKIEAETRAL--------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C6M1-1", "uniprot_id": "UBP20_MOUSE", "id": "Q8C6M1-1", "name": "Ubiquitin carboxyl-terminal hydrolase 20", "aln": "----------MGDARDLCPHLDCIGEVTKEDLLLKSKGTCQSCGVAGPNLWACLQVTCPYVGCGESFADHSSIHAQVKKHNLTVNLTTFRVWCYACEREVFLEQRLAVHLASSS---------------ARLSEQD--SPPPSHPLKAVPIAVADEGESESEDDDLKPRGLTGMKNLGNSCYMNAALQALSNCPPLTQFFLECGGLVRTD------------KKPALCKSYQKLISEVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLMDQLHEELKEPMVAAVAALTDARDSDSSDTDERRDGDRSPSEDEFLSCDSSSDRGEGDGQGRGGGSSKAEMELLISDEAGRAISEKERMKDRKFSWGQQRTNSEQVDEDADVDTAMAS-LDEQSREAQPPSP----RSTSPCQTPEPDNEAHIRS-----SSRPCSPVHHHHEGHSKLSSSPPRASPVRMGPS----YVLKKAQVPSTGGRRRKEQSYRSVISDVFNGSVLS-------LVQCLTCDRVSTTVETFQDLSLPIP----GKEDLAKLHSAIYQNVPAKPGACGDSYSSQGWLAFIVEYIRRFVVSCTPSWFWG----PVVTLEDCLAAFFAADELKGDNMYS------------------------CERCKKLRNGVKYCKVLCLP--------------------------------EILCVHLKRFRHEVMYSFKVSSHVSFPLEGLDLRPFLAKECTSQVTTYDLLSVICHHGTAGSGHYIAYCQNVIN-----------------------------------------------------------------------------------------------------GQWYEFDDQYVTEVHETVVQNVEAYVLFYRK------------------------------------------------------------------------------SSEEAMRERQQVVSLAAMREPSLLRFYVSREWLNKFNTFAEPGPITNHTFLCSHGGIPPNKYHYIDDLVVILPQSVWEHLYSRFGGGPAVNHLYVCSICQVEIEA--------------------------------------------------------------------------------------------------------------------------------------------------------------------LAKRRRVEIDTFIKLNKAFQAEESPAVIYCISMHWFREWEAFVKGKDSEPPGPIDNSRIAQVKGSGHIQLKQGADCGQISEETWTYLSSLYGGGPEIAIRQSVAQLPDPESLHGEQKIEAETRAL--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2K6-1", "uniprot_id": "UBP20_HUMAN", "id": "Q9Y2K6-1", "name": "Ubiquitin carboxyl-terminal hydrolase 20", "aln": "----------MGDSRDLCPHLDSIGEVTKEDLLLKSKGTCQSCGVTGPNLWACLQVACPYVGCGESFADHSTIHAQAKKHNLTVNLTTFRLWCYACEKEVFLEQRLAAPLLGSS---------------SKFSEQD--SPPPSHPLKAVPIAVADEGESESEDDDLKPRGLTGMKNLGNSCYMNAALQALSNCPPLTQFFLECGGLVRTD------------KKPALCKSYQKLVSEVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLMDQLHEELKEPVVATVA-LTEARDSDSSDTDEKREGDRSPSEDEFLSCDSSSDRGEGDGQGRGGGSSQAETELLIPDEAGRAISEKERMKDRKFSWGQQRTNSEQVDEDADVDTAMAA-LDDQPAEAQPPSP----RSSSPCRTPEPDNDAHLRS-----SSRPCSPVHHH-EGHAKLSSSPPRASPVRMAPS----YVLKKAQVLSAGSRRRKEQRYRSVISDIFDGSILS-------LVQCLTCDRVSTTVETFQDLSLPIP----GKEDLAKLHSAIYQNVPAKPGACGDSYAAQGWLAFIVEYIRRFVVSCTPSWFWG----PVVTLEDCLAAFFAADELKGDNMYS------------------------CERCKKLRNGVKYCKVLRLP--------------------------------EILCIHLKRFRHEVMYSFKINSHVSFPLEGLDLRPFLAKECTSQITTYDLLSVICHHGTAGSGHYIAYCQNVIN-----------------------------------------------------------------------------------------------------GQWYEFDDQYVTEVHETVVQNAEGYVLFYRK------------------------------------------------------------------------------SSEEAMRERQQVVSLAAMREPSLLRFYVSREWLNKFNTFAEPGPITNQTFLCSHGGIPPHKYHYIDDLVVILPQNVWEHLYNRFGGGPAVNHLYVCSICQVEIEA--------------------------------------------------------------------------------------------------------------------------------------------------------------------LAKRRRIEIDTFIKLNKAFQAEESPGVIYCISMQWFREWEAFVKGKDNEPPGPIDNSRIAQVKGSGHVQLKQGADYGQISEETWTYLNSLYGGGPEIAIRQSVAQPLGPENLHGEQKIEAETRAV--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PN09-1", "uniprot_id": "UBP20_DANRE", "id": "A5PN09-1", "name": "Ubiquitin carboxyl-terminal hydrolase 20", "aln": "----------MTDSGDLCPHLDSIGEVTKEELIQKSKGTCQSCGVGGPNLWACLQCDCPYVGCGESYSDHSTIHAQAKKHNLTVNLTTFRVWCYVCEREVFLEPKPVTPVSSAHR--------------CKPHDQDPVSQTTCYPLKAVPIAVADEEGSESEEDELKPRGLTGMKNIGNSCYMNAALQALSNCPPLTQFFQDCSGLVRTD------------KKPALCKSYQKLISELWHKKRPSYVVPTTLFHGIKLVNPMFRGYAQQDTQEFLRCLMDQLHEELKEPLFDCSGGISEVEPDLSLDSCNLVDGDRSPSEDEFLSCDSGSGSERGDGERAGGEAELLIQDECVAVRGTGGISEKERLKER---RGEERTR--EMDEDADVDTAAQDGQAERETETATPAT----AVPAPGNT-EPDNEASMHCP----SSRPCSPAHSVQELHSRLSSNPPRSSPLRTGPT----YTFKKAQMLLS-TKKKKQSRFRSVISDIFDGSILS-------LVQCLTCDRVSTTVETFQDLSLPIP----GKEDLAKLHSSIHQSAPVKAGVCTDGYAAQGWISYIMDSIRRFVVSCIPSWFWG----PMVTLEDCLAAFFAADELKGDNMYS------------------------CERCKKLRNGVKYCKVLRLP--------------------------------EILCIHLKRFRHEVMYSFKINSHVSFPLEGLDLKPFLAKESPSQITTYDLLSVICHHGTAGSGHYIAYCQNVIN-----------------------------------------------------------------------------------------------------GQWYEFDDQYVTEVHETVVQNAEAYVLFYRK------------------------------------------------------------------------------SSEESVRERQRVVALANLKEPSLLQFYISREWLNKFNTFTEPGPITNHTFLCQHGGIPPTKYHYVDDLVVILPQNVWEYLYNRFGGGPAVNHLYVCAICQVEIET--------------------------------------------------------------------------------------------------------------------------------------------------------------------LAKRRKLEIDTFIKLNKEFQAEEAPTVILCISMQWFREWENFVKGKDNEPPGPIDNSKIAVMKG-GHIQLKQGADYGQISEETWQYLLSIYGGGPEIAVRQTISPP--DTDTHGERKIEAETRAL--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "C9JVI0-1", "uniprot_id": "U17LB_HUMAN", "id": "C9JVI0-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 11", "aln": "------------------------------------------------------------MEDDSLYLGGEWQFNHFS---KLTSSRPDAAFAEIQRTSLPEKSPLSC--------------------------ETRVDLCDDLAPVARQLAPREKLPLSSRRPAA---VGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCH----------RHKGCMLCTMQAHITRALHN--PGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH------KQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGIS-----DTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGN----KIAKNVQYPECLDMQPYMSQ---TNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQE-GQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWER--------HSESVSRGREPRALGAEDTDRRAT--QGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLP-----PDVLVIHQS--KYKCGMKNHHPEQQ-----------------------SSLLNLSSTTPTHQESMNTGT---------------------------------LASLRGRARRSKGKNK---HSKRALLVCQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "C9J2P7-1", "uniprot_id": "U17LF_HUMAN", "id": "C9J2P7-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 15", "aln": "------------------------------------------------------------MEDDSLYLGGEWQFNHFS---KLTSSRPDAAFAEIQRTSLPEKSPLSC--------------------------ETRVDLCDDLAPVARQLAPREKLPLSSRRPAA---VGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCH----------RHKGCMLCTMQAHITRALHN--PGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH------KQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGIS-----DTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGN----KIDKNVQYPECLDMKLYMSQ---TNSGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQE-GQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWER--------HSESVSRGREPRALGAEDTDRRAT--QGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLP-----PDVLVIHQS--KYKCGMKNHHPEQQ-----------------------SSLLNLSSTTPTHQESMNTGT---------------------------------LASLRGRARRSKGKNK---HSKRALLVCQWSQWKYRPTRRGAHTHAHTQTHT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D6R9N7-1", "uniprot_id": "U17LI_HUMAN", "id": "D6R9N7-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 18", "aln": "------------------------------------------------------------MEDDSLYLGGEWQFNHFS---KLTSSRPDAAFAEIQRTSLPEKSPLSC--------------------------ETRVDLCDDLAPVARQLAPREKLPLSSRRPAA---VGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCH----------RHKGCMLCTMQAHITRALHN--PGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH------KQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGIS-----DTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGN----KIAKNVQYPECLDMQPYMSQ---TNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQE-GQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWER--------HSESVSRGREPRALGAEDTDRRAK--QGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLP-----PDVLVIHQS--KYKCGMKNHHPEQQ-----------------------SSLLNLSSTTPTHQESMNTGT---------------------------------LASLRGRARRSKGKNK---HSKRALLVCQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D6RJB6-1", "uniprot_id": "U17LK_HUMAN", "id": "D6RJB6-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 20", "aln": "------------------------------------------------------------MEDDSLYLGGEWQFNHFS---KLTSSRPDAAFAEIQRTSLPEKSPLSC--------------------------ETRVDLCDDLAPVARQLAPREKLPLSSRRPAA---VGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCH----------RHKGCMLCTMQAHITRALHN--PGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH------KQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGIS-----DTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGN----KIAKNVQYPECLDMQPYMSQ---PNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQE-GQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWER--------HSESVSRGREPRALGAEDTDRRAT--QGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLP-----PDVLVIHQS--KYKCGMKNHHPEQQ-----------------------SSLLNLSSTTPTHQESMNTGT---------------------------------LASLRGRARRSKGKNK---HSKRALLVCQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "C9JPN9-1", "uniprot_id": "UL17C_HUMAN", "id": "C9JPN9-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12", "aln": "------------------------------------------------------------MEEDSLYLGGEWQFNHFS---KLTSSRPDAAFAEIQRTSLPEKSPLSC--------------------------ETRVDLCDDLAPVARQLAPREKLPLSNRRPAA---VGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCH----------RHKGCMLCTMQAHITRALHN--PGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH------KQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGIS-----DTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGN----KIAKNVQYPECLDMQPYMSQ---PNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQE-GQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWER--------HSESVSRGREPRALGAEDTDRRAT--QGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLP-----PDVLVIHQS--KYKCGMKNHHPEQQ-----------------------SSLLKLSSTTPTHQESMNTGT---------------------------------LASLRGRARRSKGKNK---HSKRALLVCQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D6R901-1", "uniprot_id": "U17LL_HUMAN", "id": "D6R901-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21", "aln": "------------------------------------------------------------MEEDSLYLGGEWQFNHFS---KLTSSRPDAAFAEIQRTSLPEKSPLSC--------------------------ETRVDLCDDLAPVARQLAPREKLPLSNRRPAA---VGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCH----------RHKGCMLCTMQAHITRALHN--PGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH------KQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGIS-----DTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGN----KIAKNVQYPECLDMQPYMSQ---PNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQE-GQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWER--------HSESVSRGREPRALGAEDTDRRAT--QGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLP-----PDVLVIHQS--KYKCGMKNHHPEQQ-----------------------SSLLNLSSSTPTHQESMNTGT---------------------------------LASLRGRARRSKGKNK---HSKRALLVCQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D6RCP7-1", "uniprot_id": "U17LJ_HUMAN", "id": "D6RCP7-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 19", "aln": "------------------------------------------------------------MEEDSLYLGGEWQFNHFS---KLTSSRPDAAFAEIQRTSLPEKSPLSC--------------------------ETRVDLCDDLAPVARQLAPREKLPLSSRRPAA---VGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCH----------RHKGCMLCTMQAHITRALHN--PGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH------KQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGIS-----DTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGN----KIAKNVQYPECLDMQPYMSQ---TNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQE-GQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWER--------HSESVSRGREPRALGAEDTDRRAT--QGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLP-----PDVLVIHQS--KYKCGMKNHHPEQQ-----------------------SSLLKLSSTTPTHQESMNTGT---------------------------------LASLRGRARRSKGKNK---HSKRALLVCQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D6RA61-1", "uniprot_id": "U17LM_HUMAN", "id": "D6RA61-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 22", "aln": "------------------------------------------------------------MEDDSLYLGGEWQFNHFS---KLTSSRPDAAFAEIQRTSLPEKSPLSC--------------------------ETRVDLCDDLAPVARQLAPREKLPLSSRRPAA---VGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCH----------RHKGCMLCTMQAHITRALHN--PGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH------KQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGIS-----DTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGN----KIAKNVQYPECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQE-GQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWER--------HSESVSRGREPRALGAEDTDRRAT--QGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLP-----PDVLVIHQS--KYKCGMKNHHPEQQ-----------------------SSLLKLSSTTPTHQESMNTGT---------------------------------LASLRGRARRSKGKNK---HSKRALLVCQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "C9JLJ4-1", "uniprot_id": "U17LD_HUMAN", "id": "C9JLJ4-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 13", "aln": "------------------------------------------------------------MEEDSLYLGGEWQFNHFS---KLTSSRLDAAFAEIQRTSLPEKSPLSC--------------------------ETRVDLCDDLVPEARQLAPREKLPLSSRRPAA---VGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCH----------RHKGCMLCTMQAHITRALHN--PGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH------KQVDHPSKDTTLIHQIFGGYWRSQIKCLHCHGIS-----DTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGN----KIAKNVQYPECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQE-GQWYKMDDAEVTAASITSVLSQQAYVLFYIQKSEWER--------HSESVSRGREPRALGAEDTDRRAT--QGELKRDHPCLQAPELDEHLVERATQESTLDRWKFLQEQNKTKPEFNVRKVEGTLP-----PDVLVIHQS--KYKCGMKNHHPEQQ-----------------------SSLLNLSSSTPTHQESMNTGT---------------------------------LASLRGRARRSKGKNK---HSKRALLVCQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D6RBQ6-1", "uniprot_id": "U17LH_HUMAN", "id": "D6RBQ6-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 17", "aln": "------------------------------------------------------------MEDDSLYLGGEWQFNHFS---KLTSSRPDAAFAEIQRTSLPEKSPLSC--------------------------ETRVDLCDDLAPVARQLAPREKLPLSSRRPAA---VGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCH----------RHKGCMLCTMQAHITRALHN--PGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH------KQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGIS-----DTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGN----KIAKNVQYPECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQE-GQWYKMDDAEVTAASITSVLSQQAYVLFYIQKSEWER--------HSESVSRGREPRALGAEDTDRRAT--QGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLP-----PDVLVIHQS--KYKCGMKNHHPEQQ-----------------------SSLLNLSSSTPTHQESMNTGT---------------------------------LASLRGRARRSKGKNK---HSKRALLVCQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0WX57-1", "uniprot_id": "U17LO_HUMAN", "id": "Q0WX57-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24", "aln": "------------------------------------------------------------MEDDSLYLRGEWQFNHFS---KLTSSRPDAAFAEIQRTSLPEKSPLSC--------------------------ETRVDLCDDLAPVARQLAPREKLPLSSRRPAA---VGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCH----------RHKGCMLCTMQAHITRALHN--PGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH------KQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGIS-----DTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGN----KIAKNVQYPECLDMQPYMSQ---PNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQE-GQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWER--------HSESVSRGREPRALGAEDTDRRAT--QGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLP-----PDVLVIHQS--KYKCGMKNHHPEQQ-----------------------SSLLNLSSSTPTHQESMNTGT---------------------------------LASLRGRARRSKGKNK---HSKRALLVCQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8MUK1-1", "uniprot_id": "U17L5_HUMAN", "id": "A8MUK1-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 5", "aln": "------------------------------------------------------------MEDDSLYLRGEWQFNHFS---KLTSSRPDAAFAEIQRTSLPEKSPLSC--------------------------ETRVDLCDDLAPVARQLAPREKLPLSSRRPAA---VGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCH----------RHKGCMLCTMQAHITRALHN--PGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH------KQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGIS-----DTFDPYLDIALDIQAAQSVQQALEQLAKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGN----KIAKNVQYPECLDMQPYMSQ---PNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQE-GQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWER--------HSESVSRGREPRALGAEDTDRRAT--QGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLP-----PDVLVIHQS--KYKCGMKNHHPEQQ-----------------------SSLLNLSSSTPTHQESMNTGT---------------------------------LASLRGRARRSKGKNK---HSKRALLVCQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "C9JJH3-1", "uniprot_id": "U17LA_HUMAN", "id": "C9JJH3-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 10", "aln": "------------------------------------------------------------MEDDSLYLGGEWQFNHFS---KLTSSRPDAAFAEIQRTSLPEKSPLSC--------------------------ETRVDLCDDLAPVARQLAPREKPPLSSRRPAA---VGAGLQNMGNTCYVNASLQCLTYKPPLANYMLFREHSQTCH----------RHKGCMLCTMQAHITRALHI--PGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMRKACLPGH------KQVDRHSKDTTLIHQIFGGYWRSQIKCLHCHGIS-----DTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHNSAKVLILVLKRFPDVTGN----KIAKNVQYPECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCHNGHYSSYVKAQE-GQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWER--------HSESVSRGREPRALGVEDTDRRAT--QGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRRVEGTVP-----PDVLVIHQS--KYKCRMKNHHPEQQ-----------------------SSLLNLSSTTPTDQESMNTGT---------------------------------LASLRGRTRRSKGKNK---HSKRALLVCQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7RTZ2-1", "uniprot_id": "U17L1_HUMAN", "id": "Q7RTZ2-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1", "aln": "------------------------------------------------------------MGDDSLYLGGEWQFNHFS---KLTSSRPDAAFAEIQRTSLPEKSPLSS--------------------------ETRVDLCDDLAPVARQLAPREKLPLSSRRPAA---VGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQ----------RPKCCMLCTMQAHITWALHS--PGHVIQPS------QALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGH------KQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGIS-----DTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGN----KLAKNVQYPECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQE-VQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWER--------HSESVSRGREPRALGAEDTDRRAK--QGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLP-----PNALVIHQS--KYKCGMKNHHPEQQ-----------------------SSLLNLSSTTRTDQESMNTGT---------------------------------LASLQGRTRRAKGKNK---HSKRALLVCQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NCW0-1", "uniprot_id": "U17L3_HUMAN", "id": "A6NCW0-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3", "aln": "------------------------------------------------------------MGDDSLYLGGEWQFNHFS---KLTSSRPDAAFAEIQRTSLPEKSPLSS--------------------------ETRVDLCDDLAPVARQLAPREKLPLSSRRPAA---VGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQ----------RPKCCMLCTMQAHITWALHS--PGHVIQPS------QALASGFHRGKQEDVHEFLMFTVDAMKKACLPGH------KQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGIS-----DTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGN----KLAKNVQYPECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQE-GQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWER--------HSESVSRGREPRALGAEDTDRRAK--QGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLP-----PNALVIHQS--KYKCGMKNHHPEQQ-----------------------SSLLNLSSTTRTDQESMNTGT---------------------------------LASLQGRTRRAKGKNK---HSKRALLVCQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NCW7-1", "uniprot_id": "U17L4_HUMAN", "id": "A6NCW7-1", "name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4", "aln": "------------------------------------------------------------MGDDSLYLGGEWQFNHFS---KLTSSRPDAAFAEIQRTSLPEKSPLSS--------------------------ETRVDLCDDLAPVARQLAPREKLPLSSRRPAA---VGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQ----------RPKCCMLCTMQAHITWALHS--PGHVIQPS------QALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGH------KQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGIS-----DTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGN----KLAKNVQYPECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCHDGYYFSYVKAQE-GQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWER--------HSESVSRGREPRALGAEDTDRPAT--QGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLP-----PNVLVIHQS--KYKCGMKNHHPEQQ-----------------------SSLLNLSSMNSTDQESMNTGT---------------------------------LASLQGRTRRSKGKNK---HSKRSLLVCQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0C7I0-1", "uniprot_id": "U17L8_HUMAN", "id": "P0C7I0-1", "name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8", "aln": "------------------------------------------------------------MEDDSLYLGGEWQFNHFS---KLTSPRPDAAFAEIQRTSLPEKSPLSS--------------------------ETRVDLCDDLAPVARQLAPREKLPLSSRRPAA---VGAGLQNMGNTCYLNASLQCLTYTPPLANYMLSREHSQTCQ----------RPKCCMLCTMQAHITWALHS--PGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH------KQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGIS-----DTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYPCGLCLQRAPASNTLTLHTSAKVLILVLKRFCDVTGN----KLAKNVQYPECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCHNGYYFSYVKAQE-GQWYKMDDAEVTACSITSVLSQQAYVLFYIQKSEWER--------HSESVSRGREPRALGAEDTDRPAT--QGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLP-----PNVLVIHQS--KYKCGMKNHHPEQQ-----------------------SSLLNLSSMNSTDQESMNTGT---------------------------------LASLQGRTRRSKGKNK---HSKRSLLVCQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6R6M4-1", "uniprot_id": "U17L2_HUMAN", "id": "Q6R6M4-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17", "aln": "------------------------------------------------------------MEDDSLYLGGEWQFNHFS---KLTSSRPDAAFAEIQRTSLPEKSPLSS--------------------------EARVDLCDDLAPVARQLAPRKKLPLSSRRPAA---VGAGLQNMGNTCYENASLQCLTYTPPLANYMLSREHSQTCQ----------RPKCCMLCTMQAHITWALHS--PGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH------KQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGIS-----DTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGN----KLAKNVQYPECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQE-GQWYKMDDAKVTACSITSVLSQQAYVLFYIQKSEWER--------HSESVSRGREPRALGAEDTDRRAT--QGELKRDHPCLQAPELDERLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLP-----PNVLVIHQS--KYKCGMKNHHPEQQ-----------------------SSLLNLSSTTRTDQESVNTGT---------------------------------LASLQGRTRRSKGKNK---HSKRALLVCQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0C7H9-1", "uniprot_id": "U17L7_HUMAN", "id": "P0C7H9-1", "name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7", "aln": "------------------------------------------------------------MEDDSLYLGGDWQFNHFS---KLTSSRLDAAFAEIQRTSLSEKSPLSS--------------------------ETRFDLCDDLAPVARQLAPREKLPLSSRRPAA---VGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCH----------LHKCCMFCTMQAHITWALHS--PGHVIQPS------QVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGH------KQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVS-----DTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGN----KLAKNVQYPKCRDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQE-GQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWER--------HSESVSRGREPRALGAEDTDRPAT--QGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLP-----PNVLVIHQS--KYKCGMKNHHPEQQ-----------------------SSLLNLSSTKPTDQESMNTGT---------------------------------LASLQGSTRRSKGNNK---HSKRSLLVCQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6QN14-1", "uniprot_id": "U17L6_HUMAN", "id": "Q6QN14-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 6", "aln": "------------------------------------------------------------MEDDSLYLRGEWQFNHFS---KLTSSRPDAAFAEIQRTSLPEKSPLSC--------------------------ETRVDLCDDLAPVARQLAPREKLPLSSRRPAA---VGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCH----------RHKGCMLCTMQAHITRALHN--PGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH------KQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGIS-----DTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGN----KIAKNVQYPECLDMQPYMSQ---QNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQE-GQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWER--------HSESVSRGREPRALGSED----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B2RQC2-1", "uniprot_id": "UBP42_MOUSE", "id": "B2RQC2-1", "name": "Ubiquitin carboxyl-terminal hydrolase 42", "aln": "---------------------MTIVDKT-EPSDPST--------CQNQPGSCE-AVSPEDMDTGSASWGAVSSISDVS-SHTLPLGPVPGAVVY-SNSSVPEKSKPSP--------------------------PKDQVLGDGIAPPQKVLFPSEKICLKWQQSHR---VGAGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKTCH----------AEGFCMMCTMQTHITQALSN--PGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGS------NKLDRHTQATTLVCQIFGGYLRSRVKCLNCKGVS-----DTFDPYLDITLEIKAAQSVTKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTISLKRFANFTGG----KIAKDVKYPEYLDIRPYMSQ---PNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASN-GLWYQMNDSIVSTSDIRAVLNQQAYVLFYIRSHDVKNGGESAHPAHSPGQSSPRPGVSQRVVNNKQVAPGFIGPQLPSHVMKNTPHLNGTTPVKDTPSSSVSSPNGNTSVNRASPATASTSVQNWS---VTRPSVIPDHPKKQKITISIHNKLPARQGQAPLNNSLHGPCLEAPSKAAPSSTITNPSAIQSTSNVPTTSTS--------PSEACPKPMVNGKAKVGASVLVPYGAESSEESDEESKGLAK---ENGVDMMAGTHSDRPEAAADDGAEASSHELQEPVLLNGANSADSDS--QENSLAFDSASCQVQPELHTENLFSKLNGLPGKVTPAPLQSVPEDRILETFKLTNQAKGPAGEESWTTTGGSSPKDPVSQLEPISDEPSPLEIPEAVTNGSTQTPSTTSPLEPTISCTKEDSS-VVVSAEPVEGLPSVPALCNSTGTILGDTPVPELCDPGDLTANPSQPTEAVKGDTAEKAQDSAMAEVVERLSPAPSVLTGDGCEQKLLLYLSAEGSEETEDSSRSS-AVSADTMPPK--PDRTTTSSCEGAAEQAAGDRGDGGHVGPKAQEPSPAKEKMSSLRKVDRGHYRSRRERSSSGEHVRDSRPRPEDHHHKKRHCYSRERPKQDRHPTNSYCNGGQHLGHGDRASP-ERRSLSRYSHHHSRIRSGLEQDWSRYHHLENEHAWVRERFYQDKLRWDKCRYYHDRYTP-LYTARD-AREWRPLHG-REHDRLVQSGRPYKDSYWGRKGWELQSRGKERPHFNSPREAP--SLAVPLERHLQEKAALSVQDSSHSLPERFHEHKSVKSRKRRYETLENNDGRLEKKVHKSLEKDTLEEPRVKKHKKSKKKKKSKDKHRDRESRHQQESDFSGAYSDADLHRHRKKKKKKKRHSRKSEDFIKDVEMRLPKLSSYEAGGHFRRTEGSFLLADGLPVEDSGPFREKTKHLRMESRPDRCRLSEYGQGD--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZU96-1", "uniprot_id": "UBP42_RAT", "id": "D3ZU96-1", "name": "Ubiquitin carboxyl-terminal hydrolase 42", "aln": "---------------------MTIVDKT-EPSDPST--------CQNQPGSSE-AVSPEDMDTGSASWGAVSSISDVS-NHTLSLGPVPGAVVY-NNSSVPEKSKPSP--------------------------PKDQVLGDGIAPPQKVLFPSEKICLKWQQSHR---VGAGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKTCH----------AEGFCMMCTMQTHITQALSN--PGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGS------NKLDRHTQATTLVCQIFGGYLRSRVKCLNCKGVS-----DTFDPYLDITLEIKAAQSVTKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTISLKRFANFTGG----KIAKDVKYPEYLDIRPYMSQ---PNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASN-GLWYQMNDSIVSTSDIRSVLNQQAYVLFYIRSHDVKNGGETTHPAHSPGQSSPRPGISQRVVNSKQAAPGFIGPQLPPHVMKNTPHLNGTTPVKDTPSSSVSSPNGNTSVNRASPATASTSVQNWS---VNRPSVIPEHPKKQKITISIHNKLPVRQGQAQLNNNLHGPCLEAPSKAAPSSTITNPSAIQSTSNAPTTSVS--------PSESCPKPMVNGKAKVGSSVLVPYGAESSEESDEESKGLAK---ENGVDMMTSTQSSRPETADEDG-EASPHELQESVMLNGANSADSDS--RESSLAFDSASCQVQPDLHTENLFNKLNGLPGKVTPAPLQSVPEDKILETFKLTNQAKGPAVEESWTTTGGSSPRASVSQPEPITDETSPLEIPEAVTNGSMKTPSTTSPLEPTISCTKEDSSVVVVSAEPMEVLPSVPALCNSTGTTLGDAPVPESCDPGDLTANPSQPSQAVKGDPAENSENSTLAEVVERLSPAPSVLTGDGCEQKLFLYLSTEGSEEAEDSSRSS-AVSADTVPPQ--PDR-TTSSCAGAAEQAAGDRGDGGSVGPKAQEPSPAKEKMNSLRKVDRGHYRSRRDRSSSGEHVRDSRARPEDHHHKKRRCYSRERPKQERHPANTYCNGGQHLGHGDRASP-ERRSLSRYSHHHSRVRSGLEQDWSRYHHSENEPAWARERFYPDKMRWDKCRYYHDRYTTTLYTAREAAREWRPLHG-REHERLVQSGRPHKDSYWGRKGWDLQSRGKERPHFHSPREAP--GLAVPLERHLQEKAALSVQDSSHSLPERFHEHESVKLRKRRYETLDNNDDHPEKKVHKSLEKDALEEPRAKKHKKSKKKKKSKDKHRARDSRHQQESDFSGAYSDADLHRHRKKKKKKKRHSRKSEDFIKDVEMHLPKLSSYEAVGHFRRTEGTFLLADGLPVEDSGPFREKTKHLRMESRPDRCHLSEYGQGN--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H9J4-1", "uniprot_id": "UBP42_HUMAN", "id": "Q9H9J4-1", "name": "Ubiquitin carboxyl-terminal hydrolase 42", "aln": "---------------------MTIVDKASESSDPSA--------YQNQPGSSE-AVSPGDMDAGSASWGAVSSLNDVS-NHTLSLGPVPGAVVY-SSSSVPDKSKPSP--------------------------QKDQALGDGIAPPQKVLFPSEKICLKWQQTHR---VGAGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKTCH----------AEGFCMMCTMQAHITQALSN--PGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGS------NKLDRHTQATTLVCQIFGGYLRSRVKCLNCKGVS-----DTFDPYLDITLEIKAAQSVNKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGG----KIAKDVKYPEYLDIRPYMSQ---PNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASN-GLWYQMNDSIVSTSDIRSVLSQQAYVLFYIRSHDVKNGGELTHPTHSPGQSSPRPVISQRVVTNKQAAPGFIGPQLPSHMIKNPPHLNGTGPLKDTPSSSMSSPNGNSSVNRASPVNASASVQNWS---VNRSSVIPEHPKKQKITISIHNKLPVRQCQSQPN--LHSNSLENPTKPVPSSTITN-SAVQSTSNASTMSVSSKVTKPIPRSESCSQPVMNGKSKLNSSVLVPYGAESSEDSDEESKGLGK---ENGIGTIVSSHS--PGQDAEDE-EATPHELQEPMTLNGANSADSDSDPKENGLAPDGASCQGQPALHSENPFAKANGLPGKLMPAPLLSLPEDKILETFRLSNKLKGSTDEMSAPGAERGPPEDRDAEPQPGSPAAESLEEPDAAA-GLSSTKKAPPPRDPGTPATKEGAW------EAMAVAPEEPPPS-AGEDIVGDTAPPDLCDPGSLTGDASPLSQDAKGMIAEGPRDSALAEAPEGLSPAPPARSEEPCEQPLLVHPSGDHARDAQDPSQSLGAPEAAERPPAPVLDMAPAGHPEGDAEPSPGERVED-AAAPKAPGPSPAKEKIGSLRKVDRGHYRSRRERSSSGEPARESRSKTEGHRHRRRRTCPRERDRQDRHAP------EHHPGHGDRLSPGERRSLGRCSHHHSRHRSGVELDWVRHHYTEGERGWGREKFYPDRPRWDRCRYYHDRYAL--YAARD----WKPFHGGREHERAGLHERPHKDHNRGRRGCEP-ARERERHRPSSPRAGAPHALAPHPDRFSHDRTALVAGDNCN-LSDRFHEHENGKSRKRRHDSVENSDSHVEKKARRSEQKDPLEEPKAKKHKKSKKKKKSKDKHRDRDSRHQQDSDLSAACSDADLHRHKKKKKKKKRHSRKSEDFVKDSELHLPRVTSLETVAQFRRAQGGFPLSGGPPLEGVGPFREKTKHLRMESRDDRCRLFEYGQGKRRYLELGR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QY38-1", "uniprot_id": "F1QY38_DANRE", "id": "F1QY38-1", "name": "ubiquitinyl hydrolase 1", "aln": "---------------------MTIVDKPPEKPDLES--------VRCKHSSSITPFSSRDMESSSSSWSVGPSATELSRAKTVCMAPAIGATVNGSNNTALQVERPRE--------------------------QVGMTSGDGIALPQKVLFSPERLCLKWNQGHR---IGAGLHNLGNTCFLNSTLQCLTYTAPLANYMLTREHSKTCH----------EPGFCMMCTMQNHIIQVFAN--SGNVIKPISVLNELKRIGKHFRFGSQEDAHEFLRYTVDAMQKSCLPG-------NKLDRQTQATTFVHQIFGGYLRSRVKCLNCKAVS-----DTFDPYLDISLEIKTAQTLSKAFEQFVKPEQLDGDNAYKCSKCKKMVTASKRFTVHRSSNVLTISLKRFTNFNGG----KITKDVRYAEHLDLRPFMSQ---SHGEPQIYALYAVLVHSGFSCHAGHYYCYIKASN-GQWYQMNDSSVSLSDIRTVLNQQAYLLFYIRSPDVKNGGDFSQMNHTPGQSSPRPSIPLKMNGPQYTTTSFIGPQLPPHMLKNSSYVNGNGSSKEYHGGSKPNRN-FGGVTKIGPSHTSSSASASSSSLPVRSMGIPDSSKRPKLTFLIGQGKPVRPAQTQSS---------------PNCSLSSASHSQSTSSSTSTSTS-----------GFPQVKQVNGTHTGASFLVPYGQESSEESDQEAGVLEN---GSTKTYLAPKITNGNGVKDDAQSHDSSSLPHHTSKTNGSNGFHVCENGSDSHVCENGS----GPDHTSQNGLSKANGFN-----------HNDKVMIDPHTSSQIS----DLSCCSEMELNLKPAHNESRSSNPASS-------------DDHPCSSPSNKRLNLPSESSS------QSVAQIQSSPKES----LVLKTTDT----DLHTETASKVELTQRHATHTATGTSDLQVNNNVS-----------------LHVSHGHTSPHKLKEVYRCSEGESKEAKPSH------SDKFGSGDGWRSGEDRNRGSDRPHFSSTPK------------DRERYRHYRDHSDR------SRSRYGHSYQDSRRSTSRERYYRDRDLER----------HWDRFSH------HRREHHYFQRRHRDERDWNR------DRRFGSDSYRPSG--------YHNRNGYSNHSHRG----MEEAHGRATHTVNGSKGRP-----------------------SSPHSVS------PLPRHHKRKRSPSVD-----ARESSDECKAKKSKKKKRN--KDKHRHSDRELSEGNEDSSSKRHKKKKKKKKKRREDEERAHTGRDDALRWE-ERDCRASNSQHHSSEALHGVHRDHMEDQRQFNGHKANGLSCYSGSERDLCHTRMEKDVKCKDIDHVTTVNNTKTLSNGNGDVDGACHRTLSDSGEVTHPH-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "G5E8G2-1", "uniprot_id": "U17PD_MOUSE", "id": "G5E8G2-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein D", "aln": "--------------------------------------------------------------------------------------------MVVSLSFPEADPALSS--------------------------PGAQQLHQDEAQVVVELTANDKPSLSWECPQG---PGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEYSQTCC----------SPEGCKMCAMEAHVTQSLLHSHSGDVMKPS------QILTSAFHKHQQEDAHEFLMFTLETMHESCLQVH------RQSEPTSEDSSPIHDIFGGLWRSQIKCLHCQGTS-----DTYDRFLDVPLDISSAQSVNQALWDTEKSEELRGENAYYCGRCRQKMPASKTLHIHSAPKVLLLVLKRFSAFMGN----KLDRKVSYPEFLDLKPYLSQ---PTGGPLPYALYAVLVHEGATCHSGHYFSYVKAGH-GKWYKMDDTKVTSCDVTSVLNENAYVLFYVQQTDLKE--------VSIDMPEGRIHEVLDPEYQLKKSRR-KKHKKKSPCTEDVGEPSKNREKKATKETSLGEGKVLQEKNHKKAGQKHENTKLVPQEQN--HQKLGQKHRNNEILPQEQNHQKTGQ------------------------SLRNTEGELDLPADAIVIHL---------------------------------PRSIANWGRDTPDKVNQPWHNADRLLTSQDLVNTGQLCRQEGRRRSKKGKNKNKQGQKLLLVR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G5E8I7-1", "uniprot_id": "U17LC_MOUSE", "id": "G5E8I7-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein C", "aln": "--------------------------------------------------------------------------------------------MVVSLSFPEADPALSS--------------------------PGAQQLHQDEAQVVVELTANDKPSLSWECPQG---PGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEYSQTCC----------SPEGCKMCAMEAHVTQSLLHSHSGDVMKPS------QILTSAFHKHQQEDAHEFLMFTLETMHESCLQVH------RQSEPTSEDSSPIHDIFGGLWRSQIKCLHCQGTS-----DTYDRFLDVPLDISSAQSVNQALWDTEKSEELRGENAYYCGRCRQKMPASKTLHIHSAPKVLLLVLKRFSAFMGN----KLDRKVSYPEFLDLKPYLSQ---PTGGPLPYALYAVLVHEGATCHSGHYFSYVKARH-GAWYKMDDTKVTSCDVTSVLNENAYVLFYVQQTDLKQ--------VSIDMPEGRVHEVLDPEYQLKKSRR-KKHKKKSPCTEDAGEPCKNREKRATKETSLGEGKVLQEKNHKKAGQKHENTKLVPQEQN--HQKLGQKHRINEILPQEQNHQKAGQ------------------------SLRNTEGELDLPADAIVIHL---------------------------------LRSTENWGRDAPDKENQPWHNADRLLTSQDPVNTGQLCRQEGRRRSKKGKNKNKQGQRLLLVC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q61068-1", "uniprot_id": "U17PA_MOUSE", "id": "Q61068-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein A", "aln": "--------------------------------------------------------------------------------------------MVVALSFPEADPALSS--------------------------PDAPELHQDEAQVVEELTVNGKHSLSWESPQG---PGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEHSQTCC----------SPEGCKLCAMEALVTQSLLHSHSGDVMKPS------HILTSAFHKHQQEDAHEFLMFTLETMHESCLQVH------RQSKPTSEDSSPIHDIFGGWWRSQIKCLLCQGTS-----DTYDRFLDIPLDISSAQSVKQALWDTEKSEELCGDNAYYCGKCRQKMPASKTLHVHIAPKVLMVVLNRFSAFTGN----KLDRKVSYPEFLDLKPYLSE---PTGGPLPYALYAVLVHDGATSHSGHYFCCVKAGH-GKWYKMDDTKVTRCDVTSVLNENAYVLFYVQQANLKQ--------VSIDMPEGRINEVLDPEYQLKKSRR-KKHKKKSPFTEDLGEPCENRDKRAIKETSLGKGKVLQEVNHKKAGQKHGNTKLMPQKQ---------------------NHQKAGQ------------------------NLRNTEVELDLPADAIVIHQ---------------------------------PRSTANWGRDSPDKENQPLHNADRLLTSQGPVNTWQLCRQEGRRRSKKGQNKNKQGQRLLLVC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7M764-1", "uniprot_id": "U17PE_MOUSE", "id": "Q7M764-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein E", "aln": "----------------------------------------------------------MVVSLSFPEETGGENLPSAPLEDSSKFFEEVFGDMVFARSFPEADPALSS--------------------------PDAPELHQDEAQVVEELTTNGKHSLSWESPQG---PGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEHSQTCC----------SPEGCKMCAMEAHVTQSLLHSHSGDVMKPS------QILTSAFHKHQQEDAHEFLMFTLETMHESCLQVH------RQSDPTPQDTSPIHDIFGGWWRSQIKCLHCQGTS-----HTFDPFLDVPLDISSAQSVNQALWDTGKSEELLGENAYYCGRCRQKMPASKTLHVHIAPKVLLLVLKRFSAFTGN----KLDRKVSYPEFLDLKPYLSE---PTGGPLPYALYAVLVHDGATSNSGHYFCCVKAGH-GKWYKMDDTKVTRCDVTSVLNENAYVLFYVQQTDLKQ--------VSIDMPEGRVHEVLDPKYQLKKSRR-KKRKKQCHCTDDAGEACENREKRAKKETSLGEGKVPQEVNHEKAGQKHGNTKLVPQEQ---------------------NHQRAGQ------------------------NLRNTEVELDLPVDAIVIHQ---------------------------------PRSTANWGTDAPDKENQPWHNGDRLLTSQGLMSPGQLCSQGGR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9Q9U0-1", "uniprot_id": "U17PB_MOUSE", "id": "E9Q9U0-1", "name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein B", "aln": "--------------------------------------------------------------------------------------------MVVALSFPEADPAMSP--------------------------PSAPELHQDEAQVVEELAANGKHSLSWESPQG---PGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEHSQTCC----------SPEGCKMCAMEAHVTQSLLHTHSGDVMKPS------QNLTSAFHKRKQEDAHEFLMFTLETMHESCLQVH------RQSEPTSEDSSPIHDIFGGWWRSQIKCHHCQGTS-----YSYDPFLDIPLDISSVQSVKQALQDTEKAEELCGENSYYCGRCRQKKPASKTLKLYSAPKVLMLVLKRFSGSMGK----KLDRKVSYPEFLDLKPYLSQ---PTGGPLPYALYAVLVHEGATCHSGHYFCCVKAGH-GKWYKMDDTKVTSCDVTSVLNENAYVLFYVQQNDLKK--------GSINMPEGRIHEVLDAKYQLKKSGE-KKHNK-SPCTEDAGEPCENREKRSSKETSLGEGKVLQEQDHQKAGQKQENTKLTPQEQ---------------------NHEKGGQ------------------------NLRNTEGELDRLSGAIVVYQ---------------------------------PICTAN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B1AQJ2-1", "uniprot_id": "UBP36_MOUSE", "id": "B1AQJ2-1", "name": "Ubiquitin carboxyl-terminal hydrolase 36", "aln": "---------------------MPIVDKLKEALKPGRKDSAEDGDLGRLLAASAKKVLLQRIEFEPASKSFSYQLESLKSKYVLLSARAEGASRHRSGDELQARKPGTE--------------------------RVSGSGGDGVPAPQKVLFPVERLSLRWERVFR---VGAGLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEHARSCH----------QGGFCMLCLMQNHMVQAFAN--SGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYTIDAMQKACLNGY------AKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVS-----DTYDPYLDIALEIRQAANIVRALELFVKSDVLSGENAYMCAKCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGG----KITKDVGYPEFLNIRPYMSQ---SSGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASN-GQWYQMNDSLVHSSNVKVVLNQQAYVLFYLRIPGSKK---------SPEGPVSRVG-ATLPSRPK---------VVPEHSKKSPGNGVVPSPLMAKRQDSVMMRKLPAPEEVGVPVSRNGSLPGLKLQNGCAPAKTPAGSPSPRLTPTPTHMPTILDE--------------------PGKKVKKSAPLQSLTTSPTTSQG--------------------------------SPGTGESRS-----QRPGSWASRDTIFSTSPKLLARAITNGHRLKGEGSGVDLEKGDSSSSSPEHSASSDPAKAPQTAESRAAHACDSQGTNCPTAG--------------HPKALLNGVDAKMVKLKSPALSSTTTEPTS--------------------------------LMSPPPAKKLALSAKKASTLRRATGNDIGSPSPSAFCDLTSPMKATHPVVASTGPVSKTR-TAAPAPRPS-----THPHSAS------------------------LSSSSAKPLGTSEPQSCRPSAWTPLPQVNGHFTSHLHQLPEASEALHSPSKKRKKTPNGDPQRLGIDTLLPQCLRGAPAAARRKR--KKRCSEGEGATAPKQEGQFQDQSWSSGSQKE-------------------------------EGTQPQVNGHQVSHILDSYHVSSRKRRKRKRSEGLSQEA---------------------------TPSQDLIQHS-------------------------------CSPVDHSEPEARTELQKKKKKKRRKRKPEPQ-QDEESKHPGDQRSPRPSVTPVP-----ALSVNGHLPSDCLGLGQAPLVTWNRDQEPDVVQALLQDSSDKAYGKKVLTWDGEPSAISQDAIKDSRLARTQTVVDDWDEEFDR------GKEKKIKKFKREKKRNFNAFQKLQSRRNFWSVTHPAKVASLSYRR-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K033-1", "uniprot_id": "A0A0G2K033_RAT", "id": "A0A0G2K033-1", "name": "ubiquitinyl hydrolase 1", "aln": "---------------------MPIVDKLKEALKPGRKDSAEDGDLGKLLAASAKKVLLQRIEFEPASKSFSYQLESLKSKYVLLNPKAEGAGRHRSGDEPQARKPGTE--------------------------RMSGSGGDGVPAPQKVLFPVERLSLRWERVFR---VGAGLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEHARSCH----------QGSFCMLCVMQNHMVQAFAN--SGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYTIDAMQKACLNGY------AKLDRQTQATTLVHQIFGGYLRSRVKCSVCRSVS-----DTYDPYLDIALEIRQAANIVRALELFVKSDVLSGENAYMCAKCKKKVPASKRFSIHRTSNVLTLSLKRFANFSGG----KITKDVGYPEFLNIRPYMSQ---SSGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASN-GQWYQMNDSLVHSSNVKVVLSQQAYVLFYLRIPGSKK---------SPEGPVSRVG-ATLPSRPK---------VIPEHPKKSPGNGVVSSPLMAKRQDSLMMRKLQSPEEVGMPVSRNGSISGLKLQNGCAPAKSPAGSPSPRLAPTPTHMPTILDE--------------------PGEKVKKSAPPQSRTTSPTASQG--------------------------------FPGTGESRS-----QRPGSWASRDSIFSTSPK-LAKAITNGHRLKGEGNGVDLEKGDSSSSSPEHSASSDAAKAPQTSEGRAAHVCDSQGTNCPATG--------------HSKVLSNGVDAKMGKLKSPALSSTTTEPTS--------------------------------LMSPPPAKKLALSAKKASTLRRATGNDIGSPSPSAFCDLTSPMKATHPVVASPGPVSKTRAAAAPAPQPS-----PHPHSAS------------------------LSSSSAKPLGTSEPQSCCSSAWTPLPQVNGHFTSHLHQLPEANEALHSPSRKRKKTPSGDPQRLGRDTHLPQCLEGAPATARRKKRKKKKDLEGVGDTATQQESQSQDQPWSPRGRKE-------------------------------EGTQLQVNGHQVSHILDSYHASSRKRRKRKRSEGLSQEA---------------------------TVCQDLLQHG-------------------------------CSPADHCEPEARTELQKKK--KRRKRKPEPQ-QEEESEHPGYQRSPRPSVTPVP-----ELCVNDHLPSDRLGLGRAPLVTWNRDQEPDVVQELLQDSSDTAYGKKVLTWDGEPSAISQDAMKDSRLARTQTVVDDWDEEFDR------GKEKKIKKFKREKKRNFNAFQKLQSRRNFWSVTHPAKVASLSYRR-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P275-1", "uniprot_id": "UBP36_HUMAN", "id": "Q9P275-1", "name": "Ubiquitin carboxyl-terminal hydrolase 36", "aln": "---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQKIEFEPASKSFSYQLEALKSKYVLLNPKTEGASRHKSGDDPPARRQGSE--------------------------HTYESCGDGVPAPQKVLFPTERLSLRWERVFR---VGAGLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHARSCH----------QGSFCMLCVMQNHIVQAFAN--SGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYTIDAMQKACLNGC------AKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVS-----DTYDPYLDVALEIRQAANIVRALELFVKADVLSGENAYMCAKCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGG----KITKDVGYPEFLNIRPYMSQ---NNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASN-GQWYQMNDSLVHSSNVKVVLNQQAYVLFYLRIPGSKK---------SPEGLISRTGSSSLPGRPS---------VIPDHSKKNIGNGIISSPLTGKRQDSGTMKKPHTTEEIGVPISRNGSTLGLKSQNGCIPPKLPSGSPSPKLSQTPTHMPTILDD--------------------PGKKVKKPAPPQH--FSPRTAQG--------------------------------LPGTSNSNSSRSGSQRQGSWDSRDVVLSTSPKLLATATANGHGLKGNDESAGLDRRGSSSSSPEHSASSDSTKAPQTPRSGAAHLCDSQETNCSTAG--------------HSKTPPSGADSKTVKLKSPVLSNTTTEPAS--------------------------------TMSPPPAKKLALSAKKASTLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVASTWPVHRAR-AVSPAPQSSSRLQPPFSPHPT------------------------LLSSTPKPPGTSEPRSCS-SISTALPQVNEDLVSLPHQLPEASEPPQSPSEKRKKTFVGEPQRLGSETRLPQHIREATAAPHGKRKRKKKKRPEDTAASALQEGQTQRQPGSPMYRREGQAQL-------------------PAVRRQEDGTQPQVNGQQVGCVTDGHHASSRKRR-RKGAEGLGEEG---------------------------GLHQDPLRHS-------------------------------CSPMGDGDPEAMEESPRKK--KKKKRKQETQRAVEEDGHLKCPRSAKPQDAVVPESSSCAPSANGWCPGDRMGLSQAPPVSWNGERESDVVQELLKYSSDKAYGRKVLTWDGKMSAVSQDAIEDSRQARTETVVDDWDEEFDR------GKEKKIKKFKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRP5-3", "uniprot_id": "UBP36_DROME", "id": "Q9VRP5-3", "name": "Ubiquitin carboxyl-terminal hydrolase 36", "aln": "MPVSMAVCETANVVNAALRESLGGNSSAGSSTDQAKSGEDTNGSLQNHIVANAKRILMAKIEYEEVPNYHESVLENLKSKYIVIKPGNPGAINGFSGKNNTGKLVGANGHDNNGARKQAEHPNNQSHHINHHNHQHPTSNPNELPKPKRVLYPRENIRIGWKQSERKWQVGTGMINVGNTCYLNSTLQALLHIPALANWLVSEQAHLADCNVAE------PGSGCIICAMTKTLLATQSN---QSAVRPFLIYSKLKQICKHMVVGRQEDAHEFLRFLVEAMERAYLMRFR---NYKELDQLVKETTPLGQIFGGYLRSEVRCLSCNHVS-----ITFQHFQDLLLDIRKADSLEDAFEGHFSRERLEDMG-YKCEGCKKKVSATKQFSLERAPITLCIQLKRFS-MIGN----KLTKQISFKSRIDLSKYAARSQAAQAQPLTYRLVSMVTHLGASQHCGHYTAIGSTDT-GSFYNFDDSYVRPIAMHSVCNTNAYIMFFELDLSQAA-----------SPAANRPNGVRLTNGHSTTPVPAATVSSPSPTRFIGPQLPAGGANGYTNGNAQKTAIQFKQQNQQSPQNGLQLGTGKFQDTAKPPLVGAHAKG------EATSAPTANG-----------------------NKSSSPSSNSSSNHKSINQQQ-------------------------------YLPISSDDEDIEDEMKPR----PTTAQLPSMPNMTENHTEPKAKSPVKIQVKTPVKTPLKSLVPYESASEEEEAPLPNPRKRPSGEDSSESD-------------------------------------------------------------------------------------QESGQTNGHSKTNGSHTNGSASSSVHVNNSKQKTDAIDEIFKSLKKSADSDEDDDE------------------------------------------------EEPSIQLTNGWHPQKQSQSQSKAPPSPKTPPSPAVIKSKTGIWKVTRNDEVDAIEDDVDVVVVEGSPVKIPTPNKNHRNPFSSSKPSTDSPATPGAKRQKLLNGSALKSHQQP-----------------------------------------------------------------------------------------------------------------------------------------------------------RVGNGYQSNATSNGSTINELLKQSYRGYGSPVLSWNGKPAELEKELLVDAREQRQRDIDDDEENEMDRGRQRKVKSGSAKGNNASNSTPGYNPFQEYEGQKRWNKNGGGGGFPRFYNQNYRQNFQQRNKFKFNRFGGPGSAKFQQQRALQRHLSAGGGFSRRQPSAQQQQQT--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3V0C5-1", "uniprot_id": "UBP48_MOUSE", "id": "Q3V0C5-1", "name": "Ubiquitin carboxyl-terminal hydrolase 48", "aln": "-------------------------------------------------MAPRLQLEKAAWRWAETVRPEEVSQEHIETAYRIWLEPCIRGVCRRNCRGNPNCLVGIG---------------------------EHIWLG---EIDENSFHSIDDPNCERRKKNS----FVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYTKGDGIHGGKDYEPQTICEHLQYLFALLQNS-NRRYIDPSG-----FVKALGLDTGQQQDAQEFSKLFMSLLEDTLSKQK-----------NPDVRNVVQQQFCGEYAYVTVCNQCGRES-----KLVSKFYELELNIQGHKQLTDCISEFLKEERLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNAYIGFSESLDMEPYVEH----KGGSFVYELSAVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIEKMEGKKLQLGIEEDLE-PSKSQTRK-----------PKCGKGTHCSRNAYMLVYRLQAQEKNHTMVQVPAFLQELVDRDNSKFEEWCVEMAEMRKQSVDKGKAKHEEVKELYQRLPAGAEPYEFVSLEWLQKWLDESTPTKPIDN----------------------NACLCSHDKLHPDKISIMKRIS-------------------------------EYAANIFYSRYGGGPRLTVKALCKDCVVERCRVLRLKNQLNEDYKAVNNLLKSTMKG-DGFWVGKSSLRSWRQLALEQLDEQDGEAEQSNGKIN----------------------------------------------------------------------------------GSTFNKDESKEEKKEEEEELNFNEDILCPHGELSISENERRLVSQEAWS------------------------------------------------------KLQQYFPKAPEFPSYRECCSQCKILEREGEENEALHKMIANEQKTSLPNLFQDKNRPCLSNWPEDTDALYIVSHFFLDEWRKFVRKPARSAPVSSIGNAALLCPHGGLMFTFPSLTKEDSKLCQPLERREGGWPTAAHNNIALIWPSEWQMIQKLFVVDKVIKITRIEVGDVNPSQTQYISEPSLCPDCR-------------------------------------------------------------------EGLLCQQQRDLREYTQATIYVHKVVDNKKVMKDSAPELNVSSSETEEDKEEAKPDGEKDPDFNQSNGSTKRQKTSQQGYVAYQKQVIRRSTRHRKVRGEKALLVSANQTLKELKIQIMHAFSVAPFDQNLSIDGKILNDDCATLGTLGVIPESVILLKADEPIADYAAMDDVMQVCMPEEGFKGTGLLGH---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q76LT8-1", "uniprot_id": "UBP48_RAT", "id": "Q76LT8-1", "name": "Ubiquitin carboxyl-terminal hydrolase 48", "aln": "-------------------------------------------------MAPRLQLEKAAWRWAETVRPEEVSQEHIETAYRIWLEPCIRGVCRRNCRGNPNCLVGIG---------------------------EHIWLG---EIDENSFHNIDDPNCERRKKNS----FVGLTNLGASCYVNTFLQVWFLNLELRQALYLCPSTCSDYTKGDGIRGGKDYEPQTICEHLQYLFALLQNS-NRRYIDPSG-----FVKALGLDTGQQQDAQESSKLFMSLLEDTLSKQK-----------NPDVRNVVQQQFCGEYAYVTVCSQCGRES-----KLVSKFYELELNIQGHKQLTDCISEFLKEERLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNAYIGFSESLDMEPYVEH----KGGSFVYELSAVLIHRGVSAYSGHYIAHVKDPQSGDWYKFNDEDIEKMEGKKLQLGIEEDLTEPSKSQTRK-----------PKCGKGTHCSRNAYMLVYRLQTQEKNHTMVQVPAFLQELVDRDNSKFEEWCVEMAEMRRQSVDKGRAKHEEVKELYQRLPAGAEPYEFVSLEWLQKWLDESTPTKPIDN----------------------NACLCSHDKLHPDKISIMKRIS-------------------------------EYAADIFYSRYGGGPRLTVKALCKDCVVERCRILRLKNQLNEDYKTVNNLLKATMKGSDGFWVGKSSLRSWRQLALEQLDEQDGEAEQSNGKIN----------------------------------------------------------------------------------GSPFSKDESKEEKKEEEEELNFNEDILCPHGELSISENERRLVSQEAWS------------------------------------------------------KLQQYFPKAPEFPSYKECCSQCKILEREGEENEALHKMIAKEQKTSLPNLFQDKNRPCLSNWPEDTDALYIVSHFFLDEWRKFVRKPARSTPVSSVGNAALLCPHGGLMFTFPSLTKEDSKL------------------IALIWPSEWQMIQKLFVVDKVIKITRIEVGDVNPSQTQYISEPNLCPDCR-------------------------------------------------------------------EGLLCQQQKDLREYTQATIYVHKVVDNKKVMKDSAPELNVSSSETEEDKEEAKPDGEKDPDFNQSNGGTKRQKTSQQGYVAYQKQVIRRSTRHRKVRGEKALLVSANQTLKELKIQIMHAFSVAPFDQNLSIDGKILNDDCATLGTLGVIPESVILLKADEPIADYAAMDDVMQVCMPEEGFKGTGLLGH---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86UV5-1", "uniprot_id": "UBP48_HUMAN", "id": "Q86UV5-1", "name": "Ubiquitin carboxyl-terminal hydrolase 48", "aln": "-------------------------------------------------MAPRLQLEKAAWRWAETVRPEEVSQEHIETAYRIWLEPCIRGVCRRNCKGNPNCLVGIG---------------------------EHIWLG---EIDENSFHNIDDPNCERRKKNS----FVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEKDYEPQTICEHLQYLFALLQNS-NRRYIDPSG-----FVKALGLDTGQQQDAQEFSKLFMSLLEDTLSKQK-----------NPDVRNIVQQQFCGEYAYVTVCNQCGRES-----KLLSKFYELELNIQGHKQLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSEILDMEPYVEH----KGGSYVYELSAVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIEKMEGKKLQLGIEEDLAEPSKSQTRK-----------PKCGKGTHCSRNAYMLVYRLQTQEKPNTTVQVPAFLQELVDRDNSKFEEWCIEMAEMRKQSVDKGKAKHEEVKELYQRLPAGAEPYEFVSLEWLQKWLDESTPTKPIDN----------------------HACLCSHDKLHPDKISIMKRIS-------------------------------EYAADIFYSRYGGGPRLTVKALCKECVVERCRILRLKNQLNEDYKTVNNLLKAAVKGSDGFWVGKSSLRSWRQLALEQLDEQDGDAEQSNGKMN----------------------------------------------------------------------------------GSTLNKDESKEERKEEEE-LNFNEDILCPHGELCISENERRLVSKEAWS------------------------------------------------------KLQQYFPKAPEFPSYKECCSQCKILEREGEENEALHKMIANEQKTSLPNLFQDKNRPCLSNWPEDTDVLYIVSQFFVEEWRKFVRKPTRCSPVSSVGNSALLCPHGGLMFTFASMTKEDSKL------------------IALIWPSEWQMIQKLFVVDHVIKITRIEVGDVNPSETQYISEPKLCPECR-------------------------------------------------------------------EGLLCQQQRDLREYTQATIYVHKVVDNKKVMKDSAPELNVSSSETEEDKEEAKPDGEKDPDFNQSNGGTKRQKISHQNYIAYQKQVIRRSMRHRKVRGEKALLVSANQTLKELKIQIMHAFSVAPFDQNLSIDGKILSDDCATLGTLGVIPESVILLKADEPIADYAAMDDVMQVCMPEEGFKGTGLLGH---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53874-1", "uniprot_id": "UBP10_YEAST", "id": "P53874-1", "name": "Ubiquitin carboxyl-terminal hydrolase 10", "aln": "-----------------------------------MTTQESIKPLVDRILSNPLQFNAAMISNKSNNNDTSAAPENSS--YIVIGKQHNNNSNSTAIAATAESKQIKE--------------------------NNLIDRPNGKKTNTVPKSMAEALLLYTSKNDK---DAADATGAKKSAELSTELSTEPPSSSSEDDKVGKEEEEEGE---------IFHEARDYVEPRKASLKERDNADKGDGEDIGEDIG--EDIGEDIGEDIGEDIGENLGSPLATIDDSSNENEK-----EKRKELSTSISSDDEIEDDEDEDDMDYDSSAMEKELPEEEENDSSSKISEGEKKSLYQDLMENSTVEVNRYEPVNNTKENGNRNPKGEEEEEEEEELKHKSRSITPPVTISNLSN-FYQFNENINDRGSLNSTRIVKN----WGDKFTNLKPRGLLNHGVTCYTNAAVQAMLHIP-SIQHYLFDILMGKYDSTISKNSVSYTLAETSKKMWLP---------VSKNPRKNVSASYINPKHLISRLDDINCMMSEWQQEDSHEYFMSLMSRLQEDSVPKGHKLIESIIYDIFGGLLKQIVTCKSCG----SISKTEQPFYDLSLHLKGKKKLDP-----------------------NSDLSSDSINGTSATTSTTTS----------------------------------NAATKPSLSSSSSVN---LNNGSPFAAASDLSSANRRFSIEKSIKDFFNPELIKVDKEQKGYVCEKCHKTTN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AVKHSSILRAPETLLVHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCESKELPVKYQLLSVVVHEGRSLSSGHYIAHCKQPDGSWATYDDEYINIISE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------RDVLKEPNAYYLLYTRLTPKSVPLPLAKSAMATGNVTSKSKQEQAVNEPNNRPLKINSKKNNRKKWKKNKKRKFTK-----------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . :. : : :* * : : . . . . . : : . : : . : : ", "identical_positions": 2, "similar_positions": 23, "identity": "0.14%" }, { "cls_id": "homologset.agr.SGD:S000005131", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XII5-1", "uniprot_id": "TCAB1_RAT", "id": "Q5XII5-1", "name": "Telomerase Cajal body protein 1", "aln": "--------MKTSEELRLAPDSLPSDLVPAPVL---QASPADKNTDSEPVPPPCGGDDQLQVATDAVASSVVSQELQQGD----SAPLEVEFNISSELSPRIE--EQEVPENASLPVEETN---------RPELESGEAMEGVSEEPAAVDEGDIFWSYSFSQVPQYLSGSWSEF-------STRSENFLKGCKWAPDGSCILTNSADNVLRIYNLPPELYSE---SEQVDYAEMVPVLRMVEGDTIYDYCWYSLMSSTQPDTSYVASS-----SRENPIHIWDAFTGELRASFRAYNHLD-ELTAAHSLCFSPDGSQLFCGFNRTVRVFSTSRPGRDCEVRTTFAKKQGQSGIISCLAFSPA------QPLYACGSYG-RTLGLYAWDDGSPLALLGG-HQGGITHLCFHPDGN---LFFSGARKDAELLCWDLRQPGHLLWSLSR--EVTTNQRIYFDLDPSGQFLVSGNTSGVVSVWDISGAFSDC--KQLEPVMTFLPQDDCTNGVSLHPTLPLLATASGQRMFPEPTNSGD----EGEPELDLPLLSLRHAHP-----ECQLQLWWCGGGPDPSNPDEDQDEKGQGRTEA-VGMS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VC51-1", "uniprot_id": "TCAB1_MOUSE", "id": "Q8VC51-1", "name": "Telomerase Cajal body protein 1", "aln": "--------MKTSEERLLAPDSLPPDLAPAPVP---QGSPAEKNTDFEPVPPPCGGDDQPQLATDPVASLVVSQELQQGD----SVPLEVEFNTSSELSPGIE--EQDVSEHASLPGEETN---------LPELESGEATEGVSEERAEVDEGDTFWTYSFSQVPRYLSGSWSEF-------STRSENFLKGCKWAPDGSCILTNSADNVLRIYNLPPELYSE---QEQVDYAEMVPVLRMVEGDTIYDYCWYSLMSSTQPDTSYVASS-----SRENPIHIWDAFTGELRASFRAYNHLD-ELTAAHSLCFSPDGSQLFCGFNRTVRVFSTSRPGRDCEVRATFAKKQGQSGIISCIAFSPS------QPLYACGSYG-RTIGLYAWDDGSPLALLGG-HQGGITHLCFHPDGN---LFFSGARKDAELLCWDLRQPGHLLWSLSR--EVTTNQRIYFDLDPSGQFLVSGNTSGVVSVWDISGALSDD--SKLEPVVTFLPQKDCTNGVSLHPTLPLLATASGQRVFPEPTNSGD----EGELELELPLLSLCHAHP-----ECQLQLWWCGGGPDPSSPVDDQDEKGQRRTEA-VGMS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BUR4-1", "uniprot_id": "TCAB1_HUMAN", "id": "Q9BUR4-1", "name": "Telomerase Cajal body protein 1", "aln": "--------MKTLETQPLAPDCCPSDQDPAPAHPSPHASPMNKNADSELMPPPPERGDPPRLSPDPVAGSAVSQELREGDPVSLSTPLETEFGSPSELSPRIE--EQELSENTSLPAEEANGSLSEEEANGPELGSGKAMEDTSGEPAAEDEGDTAWNYSFSQLPRFLSGSWSEF-------STQPENFLKGCKWAPDGSCILTNSADNILRIYNLPPELYHE---GEQVEYAEMVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASS-----SRENPIHIWDAFTGELRASFRAYNHLD-ELTAAHSLCFSPDGSQLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPA------QPLYACGSYG-RSLGLYAWDDGSPLALLGG-HQGGITHLCFHPDGN---RFFSGARKDAELLCWDLRQSGYPLWSLGR--EVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGND---GKPEPVLSFLPQKDCTNGVSLHPSLPLLATASGQRVFPEPTESGD----EGE-ELGLPLLSTRHVHL-----ECRLQLWWCGGAPDSSIPDDHQGEKGQGGTEGGVGELI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P3C1-1", "uniprot_id": "A0A8M1P3C1_DANRE", "id": "A0A8M1P3C1-1", "name": "Telomerase Cajal body protein 1", "aln": "--------MSGVAQSGEGAAGQEAEADGEPPHEALVQGALEEEEEPAAKQPRLQQEDVALDFPMIEIAHEPSEEKSKSQD-AAGVEEEVSYHQTDEPVHVAE--HAEMERDNEWHQNGAE--------SREMLEQTEENTADEPEKNSPEAEQHYQGLDFRQNPQMLTGSWAEY-------THSAENYLRGCKWAPDGSCIVSNSADNVLRVYNLPAELYS----SQWDLLSEMSPVLKMAEGDTIYDYCWFPKMTSTDPDTCFIASS-----SRDNPVHIWDAFYGDLRASFRPYNHLD-ELTAAHSLCFSPDGSQLYCGFDKIVRVFHTDRPGRDCEQRPTMVKKRGQTGIISCIAFSQC------HSMYACGSYS-RSVGLYSCDDGSLLALLPTRHHGGLTHLLFSPNGY---HLYTGGRKDSEILCWDLRDPGQVLFSMQR--NVNTNQRIYFDLDQSGRYLLSGDTDGVVSVWDTLTALPDGNEEILKPLLQFQAHTDCTNGISVHPFMPLMASSSGQRKFFWPSDSED----STSDSEEGNVMPTNGDRP-----DNALVLWWAG-------PVASTNEIRQEEEPAVIDS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6NL34-1", "uniprot_id": "TCAB1_DROME", "id": "Q6NL34-1", "name": "Telomerase Cajal body protein 1 homolog", "aln": "MIENSFKMEMHFKNRWQAASLFLRYPRTVTLCLSGKSGDMDESVNLSTSMGDVEASMLNHNVSFSSTMVTSNGDLSLPKLSVTLSAEEILKLRSGRPKNAVESPHAGVPMETSLAAEEEANG----DEEEESVRVVDIEDTLELTSNGNEAKPEDQELAIAPVLQYFQGALVELGRRCWTSSTEAQHYTKGCYWSPDGTCLLVPVHLDGMHVIEMPSDLYSADTVQPARSLTKLQSEVHVPEGGTVYDCVWYPHMNSLQPETCLWLAT-----RQHEPIHMWDAFDGSLRCSYSGYDAVD-EVMAAISLAFSHDGEQIYAGYKRCIKIFDTSRPGRFCD---DYPVKFAISCIAQTTAHPHT------LTCGNWHGYI-QHFDLRCSHKQGPLFTLGG-HKGGITQLRYGEFGNGEWHLFSGARKCDKILQWDMRNYKQPLVELQR--HVDTNQRIQFDLASDSNWLASGDTRGFVNVWDLKKYGDPS---------VLPLHSDCCNGVALNPAMPILATSSGQFHFTDQSAQGDNVTLNGTETTELPAPADVNQNQKEVLYENAVVMWWCGQTG-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53873-1", "uniprot_id": "SWT21_YEAST", "id": "P53873-1", "name": "Protein SWT21", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKKVICQDIFWSCDGTSFVSVHNDFGIRQYLVPEESNTD-----KLNRNLLLPFTRFFRNQSIVSCAIDPFYTLYNENSDRLAGDRIVVGGKNFPLQLYSLMDGQCILSYDTMNKINGEYETVYSVKIDVESRVYTGSCRNKVAIYDKSRRDAVWMNQSTKKASKGRQSIISCFEEQPMGGQALSRGSLLCGSYANEMFQVDCRHQRLERLNYTRTVAGGIVQILTSDNGR---YVYVVRRNSDAISIYDRRNLQHELNVLRLPFRIHHNSAKLKAYIDTAYGLSMGTPQGTILNWGRDLVEFGG-----------VPSHNSVEDPLITSIPPESEWRTNLDSTIPATVVKN-----CPGDPELFALSHG----------GTISLCRFGG---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. *: **:.:: :: :* : : . :. .. :: . . . : :: . :. *::::. : *. *: : :: * :. *: :. :. . . : :: . * . . . * . .* . . : . .. **:.:: * .: *: : :* *: * : .: *. . * * . * : *. :. :. : . * :. : : . : : * ", "identical_positions": 26, "similar_positions": 95, "identity": "4.33%" }, { "cls_id": "homologset.agr.SGD:S000005133", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35344-1", "uniprot_id": "IMA4_MOUSE", "id": "O35344-1", "name": "Importin subunit alpha-4", "aln": "----------------------------------------------------------------------------------------------------MAENPGLENHRIKSFKNKG-RDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQE----------------------ESLEDSDVDADFK-------AQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKS-GILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFINP----SIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGR--KDQVEYLVQQN-VIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGD-------EASTIAEIIEECGGLEKIEVLQQHENEDIYKLAFEIIDQYFSGDDIDEDPSLIPEATQGGTYNFDPTAN-LQTKEFNF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZWC6-1", "uniprot_id": "A0A8I5ZWC6_RAT", "id": "A0A8I5ZWC6-1", "name": "Importin subunit alpha", "aln": "----------------------------------------------------------------------------------------------------MAENPGLENHRIKSFKNKG-RDLKTMRRHRNEVTVELRKNKRDEHLLKKRNVPQE----------------------ESLEDSDVDADFK-------AQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKS-GILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFINP----SIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGR--KDQVEYLVQQN-VIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGD-------EASTIAEIIEECGGLEKIEVLQQHENEDIYKLAFEIIDQYFSGDDIDEDPSLIPEATQGGTYNFDPTAN-LQTKEFNF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00505-1", "uniprot_id": "IMA4_HUMAN", "id": "O00505-1", "name": "Importin subunit alpha-4", "aln": "----------------------------------------------------------------------------------------------------MAENPSLENHRIKSFKNKG-RDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQE----------------------ESLEDSDVDADFK-------AQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKS-GILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISP----SIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGR--KDQVEYLVQQN-VIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGD-------EASTIAEIIEECGGLEKIEVLQQHENEDIYKLAFEIIDQYFSGDDIDEDPCLIPEATQGGTYNFDPTAN-LQTKEFNF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35343-1", "uniprot_id": "IMA3_MOUSE", "id": "O35343-1", "name": "Importin subunit alpha-3", "aln": "----------------------------------------------------------------------------------------------------MADNEKLDNQRLKNFKNKG-RDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPQE----------------------DICEDSDIDGDYR-------VQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKS-GILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISP----SIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGR--KDQVAYLIQQN-VIPPFCNLLTVKDAQVVQVVLDGLSNILKMAED-------QAETIANLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFFSSDDIDEDPSLVPESVQGGTFGFNSSTN-VPTEGFQF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FQB8-1", "uniprot_id": "F7FQB8_RAT", "id": "F7FQB8-1", "name": "", "aln": "MGVAAKPGPQIEAASPSQPAAHSAAVAAAGPAVVFARAAVVPGLRAGEGSQGAEAGRARGRERTGGRRRRRPASWERRCGAVVGADPAGPGRGGRVAGPAMADNEKLDNQRLKNFKNKG-RDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPQE----------------------DICEDSDIDGDYR-------VQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKS-GILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISP----SIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGR--KDQVAYLIQQN-VIPPFCNLLTVKDAQVVQVVLDGLSNILKMAED-------QAETIANLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFFSSDDIDEDPSLVPESVQGGTFGFNSSTN-VPTEGFQF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00629-1", "uniprot_id": "IMA3_HUMAN", "id": "O00629-1", "name": "Importin subunit alpha-3", "aln": "----------------------------------------------------------------------------------------------------MADNEKLDNQRLKNFKNKG-RDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHE----------------------DICEDSDIDGDYR-------VQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKS-GILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISP----SIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGR--KDQVAYLIQQN-VIPPFCNLLTVKDAQVVQVVLDGLSNILKMAED-------EAETIGNLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFFSSDDIDEDPSLVPEAIQGGTFGFNSSAN-VPTEGFQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V455-1", "uniprot_id": "Q9V455_DROME", "id": "Q9V455-1", "name": "Importin subunit alpha", "aln": "-------------------------------------------------------------------------------------------------------MTSMEQNRLQNFKNKG-KDQDEMRRRRNEVTVELRKNKREETILKRRNVPNL----------------------DSNTDEEEQLSSS-------IDLKKLAKAAADATKPEQ--QLAAVQAARKLLSSDKNPPINDLIQS-DILPILVECLKQHNHTMLQFEAAWALTNIASGTSAQTNEVVAAGAVPLFLQLLNSPAPNVCEQAVWALGNIIGDGPLLRDFVIKHGVVQPLLSFIKP----DIPITFLRNVTWVIVNLCRNKDPAPPTATIHEILPALNVLIHHTDTNILVDTVWAISYLTDGGNDQIQMVIESGVVPKLIPLLGNSEVKVQTAALRAVGNIVTGSDEQTQVVLNYDALSYFPGLLSHPKEKIRKEAVWFLSNITAGNQSQVQAVINVGLLPKIIENLSKGEFQTQKEAAWAISNLTISGN--REQVFTLIKEG-VIPPFCDLLSCQDTQVINVVLDGLNNMLKVADS-------HVEAVANCIEECEGLAKIERLQSHENVEIYKLAYEIIDQYFTDE--GEQTNMAPTS-DGAQYNFDPHADRLTMNSFNF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q56R16-1", "uniprot_id": "IMA6_RAT", "id": "Q56R16-1", "name": "Importin subunit alpha-6", "aln": "--------------------------------------------------------------------------------------------------MDSMASPGKDNYRMKSYKNKA-LNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLP--------------RND-----DCMLESPIQDPDVSSTVPIPEEDMITADMIQMIFSNNAEQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIRLLTSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTN----SNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQVVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLGSPKESVRKEACWTISNITAGNRMQIQAVIDGSIFPVLIEVLQKAEFRTRKEAAWAITNATSGGA--PEQIRYLVTLG-CIKPLCDLLTVMDSKIVQVALNGLENILRLGERESKQNGVGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIERYFGVEE-DDPSLVPQVDEQQRQFLFQQCEA--PGEGFQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15131-1", "uniprot_id": "IMA6_HUMAN", "id": "O15131-1", "name": "Importin subunit alpha-6", "aln": "--------------------------------------------------------------------------------------------------MDAMASPGKDNYRMKSYKNKA-LNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLP--------------RND-----ESMLESPIQDPDISSTVPIPEEEVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTN----SNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGT--PEQIRYLVALG-CIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVEE-DDPSIVPQVDENQQQFIFQQQEA--PMDGFQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q503E9-1", "uniprot_id": "IMA6_DANRE", "id": "Q503E9-1", "name": "Importin subunit alpha-6", "aln": "--------------------------------------------------------------------------------------------------MDAMASPGKDNYRMKSYKNKA-LNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLP--------------PGD-----ESMLECPIQDPDVSSTVPVSGEGVITQDVIQMIFSEDPDQQLIATQKFRKLLSKEPNPPIDEVIGTPGVVNRFVEFLRRSDNCTLQFEAAWALTNIASGTFQHTKVVIETGAVPIFIELLNSEYEDVQEQAVWALGNIAGDNAECRDYVLNCGILPSLQQLLAK----SNRLTTTRNAVWALSNLCRGKNPPPDFAKVSPCLSVLSRLLFSSDPDVLADACWALSYLSDGPNDKIQTVIDSGVCRRLVELLMHSDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIKKEACWTVSNITAGNRAQIQAVIDSNVFPVLIEILQKAEFRTRKEAAWAITNATSGGT--PEQIRYLVSLN-TIKPMCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGTGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVEE-EDASIVPQVDQNQGQYIFQQSEG--PMEGFQL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O60684-1", "uniprot_id": "IMA7_HUMAN", "id": "O60684-1", "name": "Importin subunit alpha-7", "aln": "--------------------------------------------------------------------------------------------------METMASPGKDNYRMKSYKNNA-LNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELI--------------NEE-----AAMFDSLLMDSYVSSTT---GESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTK----STRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGT--PEQIRYLVSLG-CIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVED-DDSSLAPQVDETQQQFIFQQPEA--PMEGFQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JZS1-1", "uniprot_id": "A0A0G2JZS1_RAT", "id": "A0A0G2JZS1-1", "name": "Importin subunit alpha", "aln": "--------------------------------------------------------------------------------------------------METMASPGKDNYRMKSYKNNA-LNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELI--------------NEE-----AAMFDSLLMDSYVSSTT---GESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPGVVDRFVEFLKRSENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTK----STRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSSKESIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGT--PEQIRYLVSLG-CIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVED-DDSSLAPQVDETQQQFIFQQPEA--PMEGFQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35345-1", "uniprot_id": "IMA7_MOUSE", "id": "O35345-1", "name": "Importin subunit alpha-7", "aln": "--------------------------------------------------------------------------------------------------METMASPGKDNYRMKSYKNNA-LNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELI--------------NEE-----AAMFDSLLMDSYVSSTT---GESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPGVVDRFVEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSLCRDYVLNCSILNPLLTLLTK----STRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSSKESIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGT--PEQIRYLVSLG-CIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKRSGSGVNPYCGLIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVED-DDSSLAPQVDETQQQFIFQQPEA--PMEGFQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q60960-1", "uniprot_id": "IMA5_MOUSE", "id": "Q60960-1", "name": "Importin subunit alpha-5", "aln": "-----------------------------------------------------------------------------------------------------MSTPGKENFRLKSYKNKS-LNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATA--------------EEE--TEEEVMSDGGFHEAQINNMEMA-PGGVITSDMTDMIFSNSPEQQLSATQKFRKLLSKEPNPPIDEVINTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRNVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLNCNILPPLLQLFSK----QNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANMFPALISILQTAEFRTRKEAAWAITNATSGGS--AEQIKYLVELG-CIKPLCDLLTVMDAKIVQVALNGLENILRLGEQEAKRNGSGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGTED-EDSSIAPQVDLSQQQYIFQQCEA--PMEGFQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P83953-1", "uniprot_id": "IMA5_RAT", "id": "P83953-1", "name": "Importin subunit alpha-5", "aln": "-----------------------------------------------------------------------------------------------------MSTPGKENFRLKSYKNKS-LNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATA--------------EEE--TEEEVMSDGGFHEAQINNMEMA-PGGVITSDMTEMIFSNSPEQQLSATQKFRKLLSKEPNPPIDEVINTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSK----QNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANMFPALISILQTAEFRTRKEAAWAITNATSGGS--AEQIKYLVELG-CIKPLCDLLTVMDAKIVQVALNGLENILRLGEQEAKRNGSGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGTED-EDSSIAPQVDLSQQQYIFQQCEA--PMEGSQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52294-1", "uniprot_id": "IMA5_HUMAN", "id": "P52294-1", "name": "Importin subunit alpha-5", "aln": "-----------------------------------------------------------------------------------------------------MTTPGKENFRLKSYKNKS-LNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATA--------------EEE--TEEEVMSDGGFHEAQISNMEMA-PGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSK----QNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGS--AEQIKYLVELG-CIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGTED-EDSSIAPQVDLNQQQYIFQQCEA--PMEGFQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TBY9-1", "uniprot_id": "A0A8N7TBY9_DANRE", "id": "A0A8N7TBY9-1", "name": "Importin subunit alpha", "aln": "--------------------------------------------MATLFVTQNWQHREADMRFAHDVLSQCACAVSLYRRRLNGCSLNDAGINEAVLTADNIMSQGKDNARLKSYKNKS-LNTDEMRRRREEEGLQLRKQKKDEQLFKRRNVATV--------------EEDGALEDDGMSDSGYLESQANNMDQI-TGSVISEDMIQMIFSSSPEQQLIGTQRFRKLLSKEPNPPIDEVIATPGVVERFVEFLKRRENCTLQFEAAWVLTNIASGTSHQTRVVIQAGAVPIFIEMLSSDFEDVQEQAVWALGNIAGDSTECRDYVLDCNILPSLVQLLAK----QNRLTMMRNAVWALSNLCRGKNPPPDFAKVSPCLSVLSWLLFVNDTDILADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLLHAEYKVVSPALRAVGNIVTGDDLQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQMVIDADLFPPLISILQVAEFRTRKEAAWAITNATSGGS--AEQIRHLVELG-CIKPLCDLLTLMDSKIVQVALNGLENILRLGELEAKRGG-GINPYCALIEEAYGLDKLEFLQGHENQEIYQKAFDLIERYFSTDD-EDPSLAPAVDLQQQQFLFQQCEA--PMEGFQL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O76521-1", "uniprot_id": "O76521_DROME", "id": "O76521-1", "name": "Importin subunit alpha", "aln": "-----------------------------------------------------------------------------------------------------MSASHK-----QRYKNAA-LDSTEMRRRREEVGIQLRKNKREQQLFKRRNVVLEPATSSTSAGVESNTDNEQQAADMHMADSSTGGQNEEAAGSGAQPSVINEEMIQMLFSGRENEQLEATQKFRKLLSRDPNPPIEEVIQK-GIVPQFVTFLRNSANATLQFEAAWTLTNIASGTSQQTKVVIEAGAVPIFIDLLSSPHDDVQEQAVWALGNIAGDSPMCRDHLLGSGILEPLLHVLSN----SDRITMIRNAVWTLSNLCRGKSPPADFAKISHGLPILARLLKYTDADVLSDTCWAIGYLSDGPNDKIQAVIDAGVCRRLVELLLHPQQNVSTAALRAVGNIVTGDDQQTQVILGYNALTCISHLLHSTAETIKKESCWTISNIAAGNREQIQALINANIFPQLMVIMQTAEFKTRKEAAWAITNATSSGT--HEQIHYLVQVG-CVPPMCDFLTVVDSDIVQVALNALENILKAGEK----FQTRPNPYAITIEECGGLDKIEYLQAHENRDIYHKSFYIIEQYFGNEE-EDSRVAPVAG--TQQFEFDPDNM--PSTGFNF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02821-1", "uniprot_id": "IMA1_YEAST", "id": "Q02821-1", "name": "Importin subunit alpha", "aln": "----------------------------------------------------------------------------------------------MDNGTDSSTSKFVPEYRRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIPP--------------TDG------ADSDEEDESSVSADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQA-GVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFN-----SNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQG-CIKPLCDLLEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIETYFGEEE-DAVDETMAPQNAGNTFGFGSNVN--QQFNFN-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P52295-1", "uniprot_id": "IMA_DROME", "id": "P52295-1", "name": "Importin subunit alpha", "aln": "------------------------------------------------------------------------------------------------------MSKADSNSRQGSYKANS-INTQDSRMRRHEVTIELRKSKKEDQMFKRRNINDE----------------------DLTSPLKELNGQS-------PVQLSVDEIVAAMNSEDQERQFLGMQSARKMLSRERNPPIDLMIGH-GIVPICIRFLQNTNNSMLQFEAAWALTNIASGTSDQTRCVIEHNAVPHFVALLQSKSMNLAEQAVWALGNIAGDGAAARDIVIHHNVIDGILPLINN----ETPLSFLRNIVWLMSNLCRNKNPSPPFDQVKRLLPVLSQLLLSQDIQVLADACWALSYVTDDDNTKIQAVVDSDAVPRLVKLLQMDEPSIIVPALRSVGNIVTGTDQQTDVVIASGGLPRLGLLLQHNKSNIVKEAAWTVSNITAGNQKQIQAVIQAGIFQQLRTVLEKGDFKAQKEAAWAVTNTTTSGT--PEQIVDLIEKYKILKPFIDLLDTKDPRTIKVVQTGLSNLFALAEKLG-----GTENLCLMVEEMGGLDKLETLQQHENEEVYKKAYAIIDTYFSNGD-DEAEQELAPQEVNGALEFNATQPKAPEGGYTF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A9QM74-1", "uniprot_id": "IMA8_HUMAN", "id": "A9QM74-1", "name": "Importin subunit alpha-8", "aln": "--------------------------------------------------------------------------------------------------MPT---LDAPEERRRKFKYRG-KDVSLRRQQRMAVSLELRKAKKDEQTLKRRNITSFCP--------------------DTPS---EKTAKGV------AVSLTLGEIIKGVNSSDPVLCFQATQTARKMLSQEKNPPLKLVIEA-GLIPRMVEFLKSSLYPCLQFEAAWALTNIASGTSEQTRAVVEGGAIQPLIELLSSSNVAVCEQAVWALGNIAGDGPEFRDNVITSNAIPHLLALISP----TLPITFLRNITWTLSNLCRNKNPYPCDTAVKQILPALLHLLQHQDSEVLSDACWALSYLTDGSNKRIGQVVNTGVLPRLVVLMTSSELNVLTPSLRTVGNIVTGTDEQTQMAIDAGMLNVLPQLLQHNKPSIQKEAAWALSNVAAGPCHHIQQLLAYDVLPPLVALLKNGEFKVQKEAVWMVANFATGAT--MDQLIQLVHSG-VLEPLVNLLTAPDVKIVLIILDVISCILQAAEKRS-----EKENLCLLIEELGGIDRIEALQLHENRQIGQSALNIIEKHFGEEE--DESQTLLSQVIDQDYEFIDYEC--LAKK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52292-1", "uniprot_id": "IMA1_HUMAN", "id": "P52292-1", "name": "Importin subunit alpha-1", "aln": "--------------------------------------------------------------------------------------------------MSTNENANTPAARLHRFKNKG-KDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPD--------------------DATSPLQENRNNQG------TVNWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRA-GLIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGT--VEQIVYLVHCG-IIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLG-----ETEKLSIMIEECGGLDKIEALQNHENESVYKASLSLIEKYFSVEE--EEDQNVVPETTSEGYTFQVQDG--APGTFNF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . . * :* ::*** *::: *:**. . : *::** : **:. :* :: : : :*:*:**.*******. :*. *: .*: :: :* : : ***:*****: **.. ** :: : : .: *. .* : **** *.* . : * * *: * : * *. **:.*::* : * *:. *: *: . : .:**::****** * **:: : . * : ** .: **: * :**::** ::* :: .:. : : .:: .:*** * ::* : .. : : *: : *: ::* * : : :. :: . . :*: *: :: * :** .: . : :*: .* * ", "identical_positions": 104, "similar_positions": 130, "identity": "15.59%" }, { "cls_id": "homologset.agr.SGD:S000005136", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M6YW55-1", "uniprot_id": "A0A8M6YW55_DANRE", "id": "A0A8M6YW55-1", "name": "chitin synthase", "aln": "MEPS---PDLKLWDVEKEENKQNEKEQQQKFWDTCREVPIIQDDQIPRNRTHCLKWFACTVVGMIVFILALLSKTSFLLLITFGNNQTVIIHSDQKPTALLAIGFVLVGPSFLLLLKGTWK-FIFKNSTMPSKKTCLWVLCVEILVALGAAVLTIVAMPHFDIVTNVMILNSVSILSAIFQVIADCRAKERKRFILLPLLSIVFIVLGYVLFVVNYLAFESSLLIPILLAIFGTICVSVNWWENYSALFTILSLNEIPKDIAKSSNAVNIISSLTRILITSAVIGVYVALIGDGWKSVKIVFETVVIALVVIQTLSSALCRWFVVVACKMHALRRSFVMPMYLASIVVLAVFLSPLVITFPVSNNTISYLVGNPVPLSSTEWVELLLIDTIETLLTRDIVVNMKIVGLVCLGCSALCWWLGLVLSTVYIWFLKIHRIERTKDLFVQRMYEGAFLEQSLMLNTR---FEIRKKIKEK--KHEKETIRVFLCATMWHETYDEMMKIIISMFRMDKYRPKTEQKSDVEFEFHIYVDDAFKDVKEER--HTNEYVEILVDVIKEVYLNFSEEDSSVFKNQQPLPSQKIISTPFGGRLEYTLPKGNVMI--VNLKDKKLIRHKKRWSQIMYLYYILGWRLHKKYYEKFEAGEDLDCLKVAGEQTESLKEKLKRERENTYILALDGDTDFQPSAVMLLIDRLKLYPDVGAACGRIHPTG-------TGPMVWYQKFEYAVGHWLQKTAEHVLGCVLCSPGCFSLFRGAALMDDNVMKRYTTRASEASHYVQYDQ----GEDRWLCTLLLQQG---WRVEYNAASDAYTNAPQDFKEFYNQRRRWGPSTMANTIDLLGSGQLTAERNSSISKLYILYQVLSMGASILGPATVCLMISGGFVFVFKMSENDALILAIVPPAIYLILCFKLKSDTQLTIAAIMSIMYAFLMTGSILSIIGDLVLQDTFLTPSGLFLIGMVVLYLITAGLHPKEFSLIIYGLLYFICIPSGYLLLAIYSIVNMNNVSWGTRESGGQAKTSAVNSLKKKFLNATCCKCPCLEYEDETRREVTQVEDKPEGENIS---EILSENTQIIPQNR----KPWIHSLQPKFGFSLRSESACELSEEELIFWKEMQKKYLHPLEEKPEQLAIIANDLRELRNKVTFVYFFCNALWLVATFFLQAIGGAVTIKIPKIYPNGTRSPTETLSLDPIALMFLLGFAALLIIQFIAMLYHRIYTFIHFVAYADTEIKAHRKQSQQVVKFMDHHETFEGDTPISTKRKSFISDGFFT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9P1A8-1", "uniprot_id": "A0A8M9P1A8_DANRE", "id": "A0A8M9P1A8-1", "name": "chitin synthase", "aln": "MKQT---PEFR------------------KFWDVGKEVPFIQDEQMPKKLTHCLKWFSCTLVGMLVFVLALLSKTSFLLLITFGNNQTEIVPLDQKPTALLAIGFVLVGPSVLLLLKSTWK-FIFKNGNMPSKKTVFWVLCVEILVALGAAVLTIVAMPHFDIVTNVMILNSISILSAFFQVDAEFLGRKRKHLLIPPFFSIFFIVLGYVLFAVNYLVFESSLRVSVGLAMFGTICVSVNWWENYSPLFTILSLKKISKDMVKSSNAVNIISSLTRILITSAVIGAYVALTGDGWKSVKIIFETVVIALVVIQTLSSALCRWFVVVACKMHALRRSFVMPMYFASIIVLAVFLSPLIYSLPLSNNTSITLEK---SESSTEWVEVLLTDAIQTLLTRDIVVNMKTEGLVCLGCSALCWWLGLVLSTIYIWFLKIHRIERTQDLFVQRMYEGAFLEQSLMLNTR---FEIGKKIKENEVAEPTKKIKVFLCATMWHETYDEMMKIIISMFRLDKYRPKHGKHSDVEFEFHIYFDDAFKDVNNGRGRLTNEYAEILVDVIKEIYIIFSEEDPCVFKEMPSLPSQKIIHTPYGGRLEYTLPNGNVMM--VHLKDKQLIRHKKRWSQIMYLYYILGWRLNKQYYENLKAGE----------EPELIKKKLKSDRENTYILALDGDTDFQPSAVMLLIDRLKIYPEVGAACGRIHPTG-------TGPVVWYQKFEYAVGHWLQKTAEHVFGCVLCSPGCFSLFRGAALMDDNVMKRYTTKASEASHYIQYDQ----GEDRWLCTLLLQQG---WRVEYNAASDAYTNAPQDFKEFYNQRRRWGPSTMANTIDLLGSGQLTAQRNSSISKLYILYQVISMAASILGPATICLMISGSFVFIFNMEENSALALAIVPPTVYLILCFKLKSDVQITIAAIMSLLYAFLMAGTVLSIIGDLVKQNTFMTPSGLFLIGMVILYLTTAALHPKEFSMVIYGLLYFICVPSGYLLLAIYSIVNMNNVSWGTRESGVQVKTSALDNIKKKFMKATCCRCPCFESEDEMNKEVLQAENTNKTEMLQMTLKIQSANDFAINTHKSVDKQTWIEHLLPKFGFCLTPES--ELSMDEIDFWIDLQKKYLEPLKENKEQQEKIANDLRELRNKATLVYFFCNALWLVATFFLQAIGEAVYIKIPKIYPNGTYAAKELLSLDPIELMFLLGFAGLLLMQFFAMLYHRIYTLIHFVAYAETEEKAPRKKVAQIVD--DNHETSEDDTICFENPYVMTRHITYV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08004-1", "uniprot_id": "CHS1_YEAST", "id": "P08004-1", "name": "Chitin synthase 1", "aln": "MSDQNNRS-------------------RNEYHSNRKNEPSYELQNAHSGLFHSSNEELTNRNQRYTNQNASMG--------SFTPVQSLQFPEQSQQTNMLYNGDDGNNNTINDNERDIYGGFVNHHRQRPPPATAEYNDVFNTNSQQLPSEHQYNNVPSYPLPSINVIQTTPELIHNGSQTMATPIERP-------------------FFNENDYYYNNRNSRTSPSIASSSDGYADQEARPILEQPNNNMNSGNIPQYHDQPFGYNNGYHGLQAKDYYDDPEGGYIDQRGDDYQIN--SYLGRNGEMVDPYDYENSLR---HMTPMERREYLHDDSRPVNDGKEELDSVKSGYSHRDLGEYDKDDFSRDD---EYDDLNTIDKLQFQANGVPASSSVSSIGSKESDIIVSNDNLTANRALKRSGTEIRKFKLWNGNFVFDSPISKTLLDQYATTTENANTLPNEFKFMRYQAVTCEPNQLAEKNFTVRQLKYLTPRETELMLVVTMYNEDHILLGRTLKGIMDNVKYMVKK------KNSSTWGPDAWKKIVVCIISDGRSKINERSLALLSSLGCYQDGFAKDEINEKKVAMHVYEHTTMINITNISESEVSLECNQGTVPIQLLFCLKEQNQKKINSHRWAFEG-------------FAELLRPN-----IVTLLDAGTMPGKDSIYQLWREFRNPNVGGACGEIRTDLGKRFVKLLNPLVASQNFEYKMSNILDKTTESNFGFITVLPGAFSAYRFEAVRGQPLQKYFYGEIMENEGFHFFSSNMYLAEDRILCFEVVTKKNCNWILKYCRSSYASTDVPERVPEFILQRRRW----------------LNGSFFASVYSFCHFYRVWSSGHNIG----RKLLLTVEFFYLFFN----TLISWFSLSSFFLVFR-------ILTVSIALAYHSAFNVLSVIFLWLYGICTLSTFILSLGNKPKSTEKFYVLTCVIFAVMMIYMIFCSIFMSVKS-------FQNILKNDTISFEGLITTEAFRDIVIS-LGSTYCLYLISSIIYLQPWHMLTSFIQYILLSPSYINVLNIYAFCNVHDLSWGTKG---------AMANPLGKINTTEDG-TFKMEVLVSSSEIQANYDKYLKVLNDFDPKSESRPTEPSYDEKKTGYYANVRSLVIIFWVITN----FIIVAVVLETG--GIADYIAMKSISTDDTLETAKKAEIPLMTSKASIYFNVILWLVALSALIRFIGCSIYMIVR--------------------FFKKVTFR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . :: . :: * : :: *. : . . * :. :* *: . :.: * :* * . :. :. : *: :: *. * : .: .: :* : : : :* .: .:: *. * : .: :* : . . :* . .. : . . :. :*.: :. . * .* . * *: **.:: : :* ..:* :.. : : :. *: .. : :* . : :: .. : :: * :: . : .: . . : :. . * .* * * :*: . : . * :.: . : : ** *:: : . . .. : : . : : ::::*:. *: :. :: :: . :: .: : :*:* :*.: :.*.. .::.. . :: : : ..*: .::.:.:: . :: : : * : * : :*: .: * * : : *: : *::* . : . : : * *:**.***.*:. .*:* *:*** :.: *:**:* :* : **.** :* *: .: : * : . * . : :.. .*** ** :: : * ::* :* * *:.*: . ** ***** *... :*: .: :*:* * . .* *::: *.::* :* : .:.:*:: :*:: :: ** : . :: : .: .**: . * . :*: *. :.. : :*: ::: . : .*:: :.:*: : : .:. : ..: . :: . : . . : : . : : : :* .*. :. : : ::* :* . *: : . * . . . ::.*. ** *:: : * :. : .* . : :::..* * * : ::: :..* ::. .: : . :* : . : ", "identical_positions": 138, "similar_positions": 386, "identity": "10.75%" }, { "cls_id": "homologset.agr.SGD:S000005141", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q01617-4", "uniprot_id": "CPO_DROME", "id": "Q01617-4", "name": "Protein couch potato", "aln": "----------------------------MLGSHHQLLIAATAAAAAAAAAEPQLQLQHLLPAAPTTPAVISNPIN--SIGPINQISSSSHPSNNN---------------QQAVFEKAITISSIAIKRRPTLPQTPASAPQVLSPSPKRQCAAAVSVLPVTVPVPVPVSVPLPVSVPVP-VSVKGHPISHTHQIAHTHQISHSHPISHPHHHQLSFAHPTQFAAAVAAHHQQQQQQQAQQQQQAVQQQQQQAVQQQQVAYAVAASPQLQQQQQQQQHRLAQFNQAAAAALLNQHLQQQHQAQQQQHQAQQQSLAHYGGYQLHRYAPQQQQQHILLSSGSSSSKHNSNNNSNTSAGAASAAVPIATSVAAVPTTGGSLPDSPAHESHSHESNSATASAPTTPSPAGSVTSAAPTATATAAAAGSAAATAAATGTPATSAVSDSNNNLNSSSSSNSNSNAIMENQMALAPLGLSQSMDSVNTASNEEEVRTLFVSGLPMDAKPRELYLLFRAYEG---YEGSLLKVTSKNGKTASPVG-----FVTFHTRAGAEAAKQDLQGVRFDPDMPQTIRLEFAKSNTKVSKPKPQPNTATTASHPALMHPLTGHLGGPFFP-------GGPELWHHPLAYSAAAAAELPGAAALQHATLVHPALHPQVPVRSYL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34761-1", "uniprot_id": "WHI3_YEAST", "id": "P34761-1", "name": "Protein WHI3", "aln": "MQSSVYFDQTGSFASSSDNVVSSTTNTHNISPSHRSSLNLNTTSHPHEASGRGSASGELYLNDTNSPLAISSMLNTLALGSMPQDIASSNISNHDNNIKGSYSLKLSNVAKDITLRECYAIFALAEGVKSIELQKKNSSSSITSASLEDENDIFIIARFELLNLAINYAVILNSKNELFGPSFPNKTTVEIIDDTTKNLVSFPSSAIFNDTSRLNKSNSGMKRPSLLSQRSRFSFSDPFSNDSPLSQQQSQQQQQQPQQPQQHSTQKHSPQQCNQQQVNSSIPLSSQGQVIGLHSNHSHQDLSVESTIQTSDIGKS--FLLRDNTEINEKIWGTSGIPSSINGYMSTPQPSTPTLEWGNTSASQHGSSFFLPSAASTAIAPTNSNTSANANASSNNGASNNGANQALSASSQQPMMQIGNTINTSLTSSNSLPPYGLMSSQSQHISNMVNTSDMNITPQKQNRFMQQPQ--PEHMYPVNQSNTPQKVPPARLSSSRNSHKNNSTTSLSSNITGSASISQADLSLLARIPPPANPADQNPPCNTLYVGNLPSDATEQELR--QLFSGQEGFRRLSFRNKNTTSNGHSHGPMCFVEFDDVSFATRALAELYGRQLPRSTVSSKGGIRLSFSKNPLGVRGPNSRRGGSGNPNPNVNMLSSYNSNVGHIKN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. *: : .::: . *: .* ..:* .**. :* ::*.: * :**: **:: :: .:.:. :* ::* :. *. *:..: *.* : : : . : :.: :* * . : *. .:. . : : .: :*.. . . . :*. ::. .:: :::.: . .:. .::..:.***.* *** :: : . ** :**: :.: :: . ::. * ::.** . : * ..:.: : *: : ::: . ** . : *. :..*.: . : . . : . .:..* . :*::.. * ::*::: ...:. .. :::::: . . : .:: *:: : .* *:*:: * .:*: * .. :*:: * .: * .** :.. ::* . :*. . * .. * * . : *.: :: .*.*.. . : . ::*::*:*: :: .. **.* :.**. . . * . .. :: ..* * :* ** .* . . .. .. . *.:. :..: : : . : ", "identical_positions": 84, "similar_positions": 260, "identity": "12.59%" }, { "cls_id": "homologset.agr.SGD:S000005144", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F6W8I0-1", "uniprot_id": "YJEN3_MOUSE", "id": "F6W8I0-1", "name": "YjeF N-terminal domain-containing protein 3", "aln": "MSSSVHNNTGPVQLPEERRFL--------------------------------------------------SASEAAALERELLE-EYRFGRQQLVELCGHASAVAVTKAFPLPSLSRKQR--TVLVVCGPEQNGAVGLACARHLRVFEYQPSIFCPARSA-DALHRDLTTQCEKMDIPFLS--FLPAEVRLIDDAYGLVVDAVLGPGVRLAEAGGHCARALATLKRLS--IPLVSLDVPSGWDAEAGGDAKDAVQPDVLVSLAAPKSCAGRFSGR--LHFVAGRFVPDDVRRKFGLHLPKYTGTDCVASL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6XGL0-1", "uniprot_id": "YJEN3_HUMAN", "id": "A6XGL0-1", "name": "YjeF N-terminal domain-containing protein 3", "aln": "MSSAAG--PDPSEAPEERHFLRALELQPPLADMGRAELSSNATTSLVQRRKQAWGRQSWLEQIWNAGPVCQSTAEAAALERELLE-DYRFGRQQLVELCGHASAVAVTKAFPLPALSRKQR--TVLVVCGPEQNGAVGLVCARHLRVFEYEPTIFYPTRSL-DLLHRDLTTQCEKMDIPFLS--YLPTEVQLINEAYGLVVDAVLGPGVEPGEVGGPCTRALATLKLLS--IPLVSLDIPSGWDAETGSDSEDGLRPDVLVSLAAPKRCAGRFSGR--HHFVAGRFVPDDVRRKFALRLPGYTGTDCVAAL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LVI2-1", "uniprot_id": "YJEN3_DANRE", "id": "Q1LVI2-1", "name": "YjeF N-terminal domain-containing 3", "aln": "MNHSSN--EKEPETIEPLRYL--------------------------------------------------SKTEVATVETELLR-DYRFGQQQLIEIWGHACAIAITKAFPLSSLSKKQP--TLLVVCGPEQNGSIGLVCARHLRMFEYEPTIFYPKRST-LGLHQDFTVQCEKMDIPFLS--YLPTEVQLLNDAYNLVIDAILGPETDHKDVKEPYAGMLVTLKQVK--IPIVSVDVPSGWDADEP--AKDGINPEVLISLTAPKKCATGFSG---KHFLAGRFLPYDIQKKYELNLPEFPGTECIIEL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8K4Z3-1", "uniprot_id": "NNRE_MOUSE", "id": "Q8K4Z3-1", "name": "NAD(P)H-hydrate epimerase", "aln": "MSGLRTLLGLGLLVAGSRLPR-----------VISQQSVCRARPIWWGTQ------RRGSETMAGAAVKYLSQEEAQAVDQELFN-EYQFSVDQLMELAGLSCATAIAKAYPPTSMSKSPP--TVLVICGPGNNGGDGLVCARHLKLFGYQPTIYYPKRPN-KPLFTGLVTQCQKMDIPFLG--EMPPEPMMVDELYELVVDAIFGFSFKG-DVREPFHSILSVLSGLT--VPIASIDIPSGWDVEKG--NPSGIQPDLLISLTAPKKSATHFTGR--YHYLGGRFVPPALEKKYQLNLPSYPDTECVYRLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0BNM1-1", "uniprot_id": "NNRE_RAT", "id": "B0BNM1-1", "name": "NAD(P)H-hydrate epimerase", "aln": "MSGLRTLLGLGLLVAGSRLPR-----------IASRQSVCRAGPIWWGTQ------HRSSETMASAAVKYLSQEEAQAVDEELFN-EYQFSVDQLMELAGLSCATAIAKAYPPTSMSKSPP--TVLVICGPGNNGGDGLVCARHLKLFGYQPTIYYPKRPN-KPLFTGLVTQCQKMDIPFLG--EMPPEPMMVDELYELVVDAIFGFSFKG-DVREPFHSILSVLSGLT--VPIASIDIPSGWDVEKG--NPSGIQPDLLISLTAPKKSATQFTGR--YHYLGGRFVPPALEKKYQLNLPAYPDTECVYRLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NCW5-1", "uniprot_id": "NNRE_HUMAN", "id": "Q8NCW5-1", "name": "NAD(P)H-hydrate epimerase", "aln": "MSRLRALLGLGLLVAGSRVPR-----------IKSQTIACRSGPTWWGPQRLNSGGRWDSEVMASTVVKYLSQEEAQAVDQELFN-EYQFSVDQLMELAGLSCATAIAKAYPPTSMSRSPP--TVLVICGPGNNGGDGLVCARHLKLFGYEPTIYYPKRPN-KPLFTALVTQCQKMDIPFLG--EMPAEPMTIDELYELVVDAIFGFSFKG-DVREPFHSILSVLKGLT--VPIASIDIPSGWDVEKG--NAGGIQPDLLISLTAPKKSATQFTGR--YHYLGGRFVPPALEKKYQLNLPPYPDTECVYRLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DHK1-1", "uniprot_id": "NNRE_DANRE", "id": "Q6DHK1-1", "name": "NAD(P)H-hydrate epimerase", "aln": "MLGVRALFGIGLLVT-SRGGF-----------VLTHTRACSSAASNIYSKHLT---HRPTCTMANTGVKYLGQEEAQQIDEELFS-DFSFSVDQLMELAGLSCATAVAKGYPVTSLLKSPA--RVLVICGPGNNGGDGLVCARHLKLFGYEPSVLYPKRPN-KQLFQNLSIQCQKMEIPFLT--EMP-EADLIDEAYSLVVDAIFGFSFKG-AVREPFGEILSQLKKIT--VPIASVDIPSGWDVEKG--CPDGIQPDMLISLTAPKKSAALFKGR--FHFLGGRFVPPVLEQKYQLNLPQYPGTECVFQLN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2Y3-1", "uniprot_id": "NNRE_DROME", "id": "Q9W2Y3-1", "name": "NAD(P)H-hydrate epimerase", "aln": "-----------------------------------------------------------------MDLKYLNQKEAIAVDQELFN-DYKFSVDQLMELAGLSCAHAVAKCFP----AEKHP--RILVCCGPGNNGGDGLVAARHLALMGYTPTIYYPKPTA-KPLFENLSHQCQQMDICDVK--ECP-SVESAARDYDLILDALFGFSFKP-PVRADFVAVVELMQQTK--LPIASVDIPSGWDVEKGKLTECDVEPALLISLTAPKLCARQFRGE--HHYLGGRFVPPALQRKYELNLPVYPGNELCVKL-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40165-1", "uniprot_id": "NNRE_YEAST", "id": "P40165-1", "name": "NAD(P)H-hydrate epimerase", "aln": "MS----------------------------------------------------------------TLKVVSSKLAAEIDKELMGPQIGFTLQQLMELAGFSVAQAVCRQFPLRGKTETEKGKHVFVIAGPGNNGGDGLVCARHLKLFGYNPVVFYPKRSERTEFYKQLVHQLNFFKVPVLSQDEGNWLEYLKPEKTLCIVDAIFGFSFKP-PMREPFKGIVEELCKVQNIIPIVSVDVPTGWDVDKGPISQPSINPAVLVSLTVPKPCSSHIRENQTTHYVGGRFIPRDFANKFGFEPFGYESTDQILKL-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "D3ZE15-1", "uniprot_id": "D3ZE15_RAT", "id": "D3ZE15-1", "name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "aln": "-------------------------------------------------------------------------MAASKVKQDMPP----------------------PGGYGPIDYKRNLP--------RRGLSGYSMFALGIGALIFGYWRIMRWNRERR-RLLIEDLEARIALMPLLQAE------------------------------KDRRTLQILRENLEEEA----IIMKDVPN--------------WKDALPGVPSTRMKVMQYSMS--QQCLLGSVHPTPPVHTWKGSEEGC----------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. :: : .. .* :. . :: * : : : : : : : : *:*. * .:. .: : : * . * ..: ", "identical_positions": 7, "similar_positions": 35, "identity": "2.24%" }, { "cls_id": "homologset.agr.SGD:S000005145", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZY13-1", "uniprot_id": "A0A8I5ZY13_RAT", "id": "A0A8I5ZY13-1", "name": "", "aln": "-----------------------MDDKLHSVKVFVLVEDEQWKIIGTGQISSKYIERLQGVCLLVHSESD-----GSQIMECKIYPNVPYHKQRGEIIVWSEAKNHGMAIYFQEPSGCQEIWEDICQVQGKDPSVEITQEVTDDLET--FADLLPIGNLFEMPNCELN----TLEHIADLFTFVDKTPNH-RERMAMVLEKGSYIKKLLQLFNTCEKLKNMEALHFLNNIIKGILFLDDTRLLNIMFSDEFFMDVVGCLEYDPALDQPKQ-YREFLLQNA-KFREIMPITNSQLRQKIQETYRMQYVYDIVLPAPSIFDSN-LLSDLNAMIIFNKSEIITMLQDDENFLLEALSQLKDNTVGY---------ERWYELLLFFKEFCIFAKALENQEKDELLKTLIKLGIMSALKVLVHMH-DYQIQKAALDIFPYLVEYNPCLVREYLLEEAQDSEDN------------DELLINVMIKQMIYDPDPEFSKDIILPAVLRALLDPENMHVTANGCEKAKFLNFFYARCMGNLIAPILSTTVENDTDDN---------------------------------------MVNICPN-YQNAQLLGVILEILTFCVQYHSTYMKNYILNNNLLSRILMLMSSKHTFLILCAVRFMRKIISLKDEIYNLYIIKKNLFEPIVNAFMHNGTRYNMLNSAIIELFEFIRQENIKSLIANIVENFFIAFESIEYVQTFKGLKTKYEE------EKKRESGIRRNLYNVIYQKIYCR-HIKVMELKVK-------------ADICCR--EITEEEG----------------------------------------AILPMGKE---FPS----------------HYDIIMKIKETN------------------------------ENENVIEHP--KSNETSKCSSSCGDASSNKMSMVHCS------------------------------------------------------------------------------------------------SLVPLVDYPYDTDGESDDDPYGND--ENDDEDKDNEPLSKRPNLSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2ADI4-1", "uniprot_id": "A2ADI4_MOUSE", "id": "A2ADI4-1", "name": "", "aln": "-----------------------MDDKLHSVKIYVMVEDEQWKGIGAGQISSKYIERLQGVCLIVQSESD-----GSLIMECKIHPNVPYHKQRGEIIIWSETKNHGMAIHFQEPNGCQEIWEDICQVQGKDPNVEITEELTDNLKT--FEELLPIWNLVEMQNCELH----TLENIADLFTFVHETPSH-KERLVLVLEKGVYIKKLLQHFNTCEKLKNMESLYYLNNIIKGILFLDNTHLFNIMFSDEFFMDMVGCLEYDPALDHPKQ-YREFLTQNA-KFKEILPITHFQLRQTIQQTYRMQYVHDIVLPIPSICESN-LLYGLNTMIIYNKIEIITMLQDDENFLLEVLARLKDNTVGN---------DRRHELLLFFKEFCTFAKTLENLEKHELLKTLINLGVMSALKAVVHMH-DYQIQIAALDIFPYLVEYNPCLVREYLLDEAHDTDD-------------DDLFLNIMIKQMICNSDPRFSQGIILPAILCALLDPENMHVTANGCEEKEFLNFFYTRCINNLIAPILSATVEKENANN---------------------------------------RANICPDNYQNAQLLGVVIEILTFCVQYHSTYIKSYILDNNLLSRILVLMTSKHTFLILCAVRFMRKLIGLKDEIYNLYIIKENLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVENFFISFESIEYVQTFKGLKIKYEE------EKN-ECQVRRNLLNVVCQKIYCI-CTNDMGLKVK-------------SDICHR--RITETKE----------------------------------------AILPNRRD---FPS----------------HYGIIMKIEETN------------------------------ESESAIEGQKIKSSEAFERCPSHGDASATRMSRSHCS------------------------------------------------------------------------------------------------SLVPLVNYPYDTDDENGDDPYGND--NDEDE----EPPQKRPNLSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3V0Y1-1", "uniprot_id": "P4R3C_MOUSE", "id": "Q3V0Y1-1", "name": "Protein PPP4R3C1", "aln": "-----------MTWPSEARPNINMEYRLHTVKVYVMMEDKQWKNVGTGQISSKYSEQLQGVCLLVHSLSD-----GSPIMECKIHPNVPYQKQQGKIIIWSEAKNHGMAIHFQEPNDCQEIWEDICQIQGKDPHVEITQELTDDLET--FEHMPLIWNWVEMSNCEIH----TLKNIAELFPFVFEMPSQ-KERLALFLENEGYIKKLLQLFHTCEKLKNMEGLYYLHNIIKGILFLNNTRLFNIMFSDEFFMDIVGCLEYDPALDQPKQ-YREFLTQNS-KFKEVIPIIHSQLRQKIQQTYRMQYVHDIMLPTPSIFQTN-LLSDITTMIFFNKINIITMIQEDENFLLEVFSQLKDNSIGD---------ERRIELLLFLKEFCEFAKTLQSQKKNELLKTLIKLGIMSVLKVVVHMN-DYQIQVGALDIFAYLVEYSPCLVRAYAMEEAQDSEDN------------DDLLINIMIKQMICDFDPEFSQGIIMTAVLHELLNPENMRTTAKGCERKVFLNFFYKRYMRKLIAPILSIRVKYDSNDN---------------------------------------RVYICPDNYQNAQLLGAVLEILTFCVQYHSMYIKHYIFSNNLLRSILVLMSSKHTFLILCAVRFMRKIIGLKDKMYNHYIIKKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRKENITSLIVNIVENFFRAFKSIEYVQTFKGLKTKYEE------EKKRKSQRRKNLHSIMHPKMYYR-HIEDMEVKVK-------------ADICCR--GIIEEEERQGGG--------------------------------EEGAILPMGSD---FTN----------------NYDIFMKNKDTN------------------------------ESESAIEGQKIKSSEASECCPSHGDASATRMSRSHCS------------------------------------------------------------------------------------------------SLVPLVDYLYDTDDENDDDPYGNDKHEDEHEDEDEEPPPKRPNLST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZMV5-1", "uniprot_id": "P4R3C_HUMAN", "id": "Q6ZMV5-1", "name": "Protein PPP4R3C", "aln": "-----------------------MAGLRYSVKVYVLNEDEEWNNLGTGQVSSTYDEQFQGMSLLVRSDSD-----GSVILRSQIPPDRPYGKYQETLIVWYEAENQGLVLKFQDPAGCQDIWKEICQAQGKDPSIQTTVNISDEPEED-FNEMSVISNMVVLPDCELN----TLDQIADIVTSVFSSPVTDRERLAEILKNEAYIPKLLQLFHTCENLENTEGLHHLYEIIKGILFLNEACLFEIMFSDECIMDVVGCLEYDPALDQPKR-HRDFLTNDA-KFKEVIPITNSELRQKIHQTYRLQYIYDILLPVPSIFEDN-FLSTLTTFIFSNKAEIVSMLQKDHKFLYEVFAQLKDETTHD---------DRRCELLFFFKELCSFSQALQPQSKDALFETLIQLGVLPALKIVMIRD-DLQVRSAAAVICAYLVEYSPSRIREFIISEAHVCKD-------------SDLFINVIIKQMICDTDPELGGAVHLMVVLHTLLDPRNMLTTPEKSERSEFLHFFYKHCMHKFTAPLLAATSEHNCEEDD---------------------------------IAGYDKSKNCPNDNQTAQLLALILELLTFCIQHHTFYIRSYILNKDLLRKALILMNSKHTHLILCVLRFMRRMICLNDEAYNNYIIKGNLFEPVVNALLDNGTRYNMLNSAILELFEYIRVENIKPLVSHIVEKFYNTLESIEYVQTFKGLKIKYEK------ERDRQSQIQKNLHSVLQNIVVFRGTIEEIGLEEEICF------MEDAGEVVMP--PLEDDDEFMETKRT-----------------------------QEGEAVMPPLEDDDKFTETKRTHQEGEAVMPPLEDDDEFMETKRNQ------------------------------EHEGKVDSPKRTSSGDFKFSSSYSACAAIGTGSPSGS------------------------------------------------------------------------------------------------SVVRLVDHPDDEEEKEEDEEEKEE--DKEDE----TSPKKKPHLSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q922R5-1", "uniprot_id": "P4R3B_MOUSE", "id": "Q922R5-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3B", "aln": "-----------------------MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESD-----GSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEERFEEMPETSHLIDLPACELS----KLEEIADLVTSVLSSPIR-REKLALALENEGYIKKLLQLFQACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKR-HREFLTKTA-KFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEEN-FLSTLTSFIFFNKVEIVSMLQEDEKFLSEVFAQLTDEATDD---------DKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMD-DLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDD-------------DVLLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLTNTSEDKCEK--------------------------------DNMLGSNTTNTICPDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGLKDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQ------EKDRQ-NQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDDD--EEGKAVITPVEKSKTEDDFPDSYEK-----------------------------FMETKKAKESEDKENLPKRASSGG-----FKFTFSHSPSATNGTNS------------------------------TNSKSVVSQTTPASSNVASS----KTTSLATSVTATKG-----------------------------------------------------------------------------------------------NLVGLVDYPDDEEEDEEEES----------------SPRKRPRLGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZCR4-1", "uniprot_id": "D3ZCR4_RAT", "id": "D3ZCR4-1", "name": "", "aln": "-----------------------MSEE---------------------SVEDHIVEDQIGISP-MRSDTDPRPALGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEERFEEMPETSHLIDLPTCELS----KLEEIADLVTSVLSSPIR-REKLALALENEGYIKKLLQLFQACENLENTEGLHQLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKR-HREFLTKTA-KFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEEN-FLSTLTSFIFFNKVEIVSMLQEDEKFLSEVFAQLTDEATDD---------DKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMD-DLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDD-------------DILLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLTNTSEDKCEK--------------------------------DNMLGSNKTNTICPDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGLKDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQ------EKDRQ-NQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDDD--EEGKSVVTPVEKTKTEDDFPDSYEK-----------------------------FMETKKAKESEDKENLPKRTSSGG-----FKFTFSHSPSAANGTNS------------------------------TNSKSVVAQTTPASSNGSSS----KTTNLATSVTATKG-----------------------------------------------------------------------------------------------SLVGLVDYPDDEEEDEEEES----------------SPRKRPRLGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5MIZ7-1", "uniprot_id": "P4R3B_HUMAN", "id": "Q5MIZ7-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3B", "aln": "-----------------------MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESD-----GSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEERFEEMPETSHLIDLPTCELN----KLEEIADLVTSVLSSPIR-REKLALALENEGYIKKLLQLFQACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKR-HREFLTKTA-KFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEEN-FLSTLTSFIFFNKVEIVSMLQEDEKFLSEVFAQLTDEATDD---------DKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMD-DLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDD-------------DILLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLTNTSEDKCEKDFFLKHYRYSWSFICTPSHSHSHSTPSSSISQDNIVGSNKNNTICPDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGLKDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQ------EKDRQ-NQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDEE--EEGKAVVAPVEKPKPEDDFPDNYEK-----------------------------FMETKKAKESEDKENLPKRTSPGG-----FKFTFSHSASAANGTN---------------------------------SKSVVAQIPPATSNGSSS----KTTNLPTSVTATKG-----------------------------------------------------------------------------------------------SLVGLVDYPDDEEEDEEEES----------------SPRKRPRLGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P2K6-1", "uniprot_id": "P4R3A_MOUSE", "id": "Q6P2K6-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3A", "aln": "-----------------------MTDTRRRVKVYTLNEDRQWDDRGTGHVSSGYVERLKGMSLLVRAESD-----GSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVDITQDLVDESEEERFDDMSSPG--LELPSCELS----RLEEIAELVASSLPSPLR-REKLALALENEGYIKKLLELFHVCEDLENIEGLHHLYEIIKGIFLLNRTALFEVMFSEECIMDVIGCLEYDPTLSQPRK-HREFLTKTA-KFKEVIPISDPELKQKIHQTYRVQYIQDMVLPTPSVFEEN-MLSTLHSFIFFNKVEIVGMLQEDEKFLTDLFAQLTDEATDE---------EKRQELVNFLKEFCAFSQTLQPQNRDAFFKTLSNMGILPALEVILGMD-DTQVRSAATDIFSYLVEYNPSMVREFVMQEAQQNDD-------------DILLINLIIEHMICDTDPELGGAVQLMGLLRTLVDPENMLATANKTEKTEFLGFFYKHCMHVLTAPLLANTTEDKPSK----------------------------------------------DDFQTAQLLALVLELLTFCVEHHTYHIKNYIINKDILRRVLVLMASKHAFLALCALRFKRKIIGLKDEFYNRYIMKSFLFEPVVKAFLNNGSRYNLMNSAIIEMFEFIRVEDIKSLTAHVIENYWKALEDVDYVQTFKGLKLRFEQ------QRERQDNPKLDSMRSILRNHRYRRDARTLEDEEEMWFNTDEDDMEDGEAVVSPSDKTKNDDDIMDPISK-----------------------------FMERKKLKESEEKEVLL-KTNLSGRQSPSFKLSLSSGTKTNLTSQS------------------------------SATSLPGSPGSPGSPGSPGSPGSVPKSTSQTAAITTKG-----------------------------------------------------------------------------------------------GLVGLVDYPDDDEDDDEDED---K--------EDTLPVSKKAKFES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AS21-1", "uniprot_id": "A0A8I6AS21_RAT", "id": "A0A8I6AS21-1", "name": "SMEK homolog 1", "aln": "-----------------------MTDTRRRVKVYTLNEDRQWDDRGTGHVSSGYVERLKGMSLLVRAESD-----GSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVDITQDLVDESEEERFDDMSSPG--LELPSCELS----RLEEVAELVASSLPSPLR-REKLALALENEGYIKKLLELFHVCEDLENIEGLHHLYEIIKGIFLLNRTALFEVMFSEECIMDVIGCLEYDPTLSQPRK-HREFLTKTA-KFKEVIPISDPELKQKIHQTYRVQYIQDMVLPTPSVFEEN-MLSTLHSFIFFNKVEIVGMLQEDEKFLTDLFAQLTDEATDE---------EKRQELVNFLKEFCAFSQTLQPQNRDAFFKTLSNMGILPALEVILGMD-DTQVRSAATDIFSYLVEYNPSMVREFVMQEAQQNDDVSKKLTEQKITSKDILLINLIIEHMICDTDPELGGAVQLMGLLRTLVDPENMLATANKTEKTEFLGFFYKHCMHVLTAPLLANTTEDKPSK----------------------------------------------DDFQTAQLLALVLELLTFCVEHHTYHIKNYIINKDILRRVLVLMASKHAFLALCALRFKRKIIGLKDEFYNRYIMKSFLFEPVVKAFLNNGSRYNLMNSAIIEMFEFIRVEDIKSLTAHVIENYWKALEDVDYVQTFKGLKLRFEQ------QRERQDNPKLDSMRSILRNHRYRRDARTLEDEEEMWFNTDEDDMEDGEAVVSPSDKTKNDDDIMDPISK-----------------------------FMERKKLKESEEKEVLL-KTNLSGRQSPSFKLSLSSGTKTNLTSQS------------------------------SATSLPGSPGSPGSPGSPGSPGSVPKSTSQPAAITTKG-----------------------------------------------------------------------------------------------GLVGLVDYPDDDEDDDEDED---K--------EDTLPVSKKAKFES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6IN85-1", "uniprot_id": "P4R3A_HUMAN", "id": "Q6IN85-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3A", "aln": "-----------------------MTDTRRRVKVYTLNEDRQWDDRGTGHVSSGYVERLKGMSLLVRAESD-----GSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVDITQDLVDESEEERFDDMSSPG--LELPSCELS----RLEEIAELVASSLPSPLR-REKLALALENEGYIKKLLELFHVCEDLENIEGLHHLYEIIKGIFLLNRTALFEVMFSEECIMDVIGCLEYDPALSQPRK-HREFLTKTA-KFKEVIPISDPELKQKIHQTYRVQYIQDMVLPTPSVFEEN-MLSTLHSFIFFNKVEIVGMLQEDEKFLTDLFAQLTDEATDE---------EKRQELVNFLKEFCAFSQTLQPQNRDAFFKTLSNMGILPALEVILGMD-DTQVRSAATDIFSYLVEYNPSMVREFVMQEAQQNDDVSKKLTEQKITSKDILLINLIIEHMICDTDPELGGAVQLMGLLRTLVDPENMLATANKTEKTEFLGFFYKHCMHVLTAPLLANTTEDKPSK----------------------------------------------DDFQTAQLLALVLELLTFCVEHHTYHIKNYIINKDILRRVLVLMASKHAFLALCALRFKRKIIGLKDEFYNRYIMKSFLFEPVVKAFLNNGSRYNLMNSAIIEMFEFIRVEDIKSLTAHVIENYWKALEDVDYVQTFKGLKLRFEQ------QRERQDNPKLDSMRSILRNHRYRRDARTLEDEEEMWFNTDEDDMEDGEAVVSPSDKTKNDDDIMDPISK-----------------------------FMERKKLKESEEKEVLL-KTNLSGRQSPSFKLSLSSGTKTNLTSQS------------------------------STTNLPGSPGSPGSPGSPGSPGSVPKNTSQTAAITTKG-----------------------------------------------------------------------------------------------GLVGLVDYPDDDEDDDEDED---K--------EDTLPLSKKAKFDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SP90-1", "uniprot_id": "PP4R3_DANRE", "id": "Q5SP90-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3", "aln": "-----------------------MTDTRRRVKVYTLNEDRQWDDRGTGHVSSAYVERLKGMSLLVRAESD-----GSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVDITQELIDESEEERFDDMSSPG--LELPPCELS----RLEEVAELVASSLPSPLR-REKLALALENEGYIRKLLELFRVCEDLENREGLHHLYDIIKGIFLLNRTALFEVMFSEECIMDVIGCLEFDPSLPQPRR-HREFLTTTA-RFKEVIPISDPELRQKIHQTYRVQYIQDMVLPTPSVFEEN-MLSTLHSFIFFNKVEIVGMLQDDEKFLTELFAQLTDEATDD---------DKRHELVNFLKEFCAFSQTLQPQNRDAFFKTLSNMGILQALEVILGMD-DVQVRGAATDIFSYLVEYNPSMVREFVMQESQQNDD-------------DILLINLIIEHMICDTDPELGGAVQLMGLLRTLVDPENMLATANKTEKTEFLSFFYKHCMHVLSAPLLANTTEEKPSK----------------------------------------------DDFQTCQLLALIVELLTFCVEHHTYHIKNYIINKDILRRVLVLTASQHAFLALCALRFMRKIIGLKDEFYNRYIMRNFLFEPVVKAFLNNGSRYNLINSAIIEMFEYVRVEDVKSLTAHIIENYWKGLEDVDYVQTFKGLKLRYEQ------QRERQDNPKLDSMRSILRNHRFRRDARTLEDEEEMWFNTDEEDLEDGEAVVPPSDKMKNDEDLMDPISK-----------------------------FMERKKLKDSEEKEVLTGKASLSGRQSPSFKLSFSSSPKASLSSPP------------------------------TASLHPGSPGSPSSPGTG------ARSSPPSAAVTTKG-----------------------------------------------------------------------------------------------GLVGLVDYPDDDEEDEDEEDADSK--------EESPPLSKKSKLSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFS5-1", "uniprot_id": "PP4R3_DROME", "id": "Q9VFS5-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3", "aln": "----------------------MTTDTRRRVKLYALNAERQWDDRGTGHVSSTYVERLKGISLLVRAESD-----GSLLLESKIQPDTAYQKQQDTLIVWSEGDNFDLALSFQEKAGCDEIWEKICQVQGKDPSVEITQDIVEESEDERFEDMSDTAPPIELPPCELS----RLEDISETIQSCLSTPLR-KEKLSMALESESYIKKLLNLFHVCEDLDNTEGLHHLFEIFKNIFLLNKNALFEIMFADDTIFDVVGCLEYDPSVSQPKK-HRQYLKQLA-KFREAVPIKNLDLLAKIHQTFRVQYIQDIILPTPSVFVEDNMLNTLSSFIFFNKVEIVTMIQDDERYLLDVFAVLTDPTTGD---------AKRRDTVLFLKEFCNYAQNLQPQGKDSFYKTLTCLGILQALELTLVMN-DKKTKSASIDILTAIVEFSPLVVRNYTLNQANRPEV-------------ERMLLNIAIEQMLNDSEPELGIAVQLMGIVKILLEPENMLT-----EKGDFLNFFYKYSVQTLVAPVILNTIGDRPQN----------------------------------------------EDYQTAQLLGIVLDILSFCVEHHSYHIKNFLLQKDLLKRILVLMKSTHTFLVLGALRLLRKIIALKDEFYNRHIVKCNLFAPVVDAFIRNNGRYNLLESAILELFEFIKLEDIRTLCVYFVENFSKIFDEIEYVQTFKYLKNRYDQYQDRLKDRDKMENRTDGGLPIIRSGGRFRRDQRQMEEEEEMWFNEEDDFTEEIDTYNNVMKSVSEKNGPQTQNQQKSSPPHSTSPHSGLLGSLSTTASSTATSATSGAPVASGSSSPEAISADEQTQAAVHLAAAALQHHQQQQQQQQQNPFQQQTQPEIAELQQQLSSVEAPQSQELELSQSAAASASPTSSSSSLEASTSSSSASSSSSSSSSSSPPGSSAAASLCDSATVAAVAASQFLSTIATAMAASVTAAAATNSSPSISPAPAVSSPDIENADAQLPPSDDASSPASGEQDANSTEGTSSEADKTTAKKGLVDYESDSGEDDYEEDEYSE----------GPQAQKRARQA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40164-1", "uniprot_id": "PP4R3_YEAST", "id": "P40164-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3", "aln": "MSLPGTPTTSPTPMDEDTEQAVSVNTEPKRVKVYILENN-EWKDTGTGFCIGEVDEGKFAYLVVSDEDSP-----TETLLKSKLEGNIEYQRQEETLIVWKDLGGKDIALSFEESMGCDTLCEFIVHVQR-NIESNISLVTVKSSDNGLGSVHDIITGPVTLPSNDQQQNSQTLLEALKILNENTSFDFLKNETIEFILQSN-YIDTLISHFHKAEEEKIPKDLFLLSNIIKTLILYNKRDILESMVEDDRIMGIVGILEYDTEYPTSKANHRKYLGSKGPNFKEVIPLENEDLKIIMKKCFRLQFLKDVVLVR---FLDDHNFNLISEIVMDLETCIIDFLQVG-TFLDRLIELYDTKTLPESSSEKEKFVQKRKDGIRLLQQCVQMSINLDAVDRSKFYKTLVRKGLFKVLDYAFHMETDSNVRILATDTIITIIEHDILLIHNVQNEDSFKRQH--------------KSAPDDKSSHRKYPQDYSSSTDSKLLLILSTILLS----------DRSPGLREQVVQALNTLLHPEGCVGNGEGSYDLMG-------------------------------------------RSNYEAKNTSEDFPSFSYGLNSDSINLNNYHYSSDEMNNLEPESESEFQVMEYFANFYNKIAPILFGPLIKKDITT---EMAEIDGQIEKVTKDDLLLIHLVKLVSFVCTEHDRVLSRRFILENGILDSVSKLIGGNHMMQLRLTAVR---CIKNLMCLDDKYYHRYMISKNLYAPVFKLFQENIDKNNLANSCIQDFFRIIITECRAYQSDGHNRKEKTN--------------------------------GSYDGNGNDVKTNVNNNRTNFTILNKYLVQTYGDVLRKATDIP----------------------------FIQDMLETGEENQPDHSSFENSIEGGNDISVNMSTDGFASN-----------------------------------------------------------------------------------------HLEDIDIKNVKRLHSEIEHFENDPHYSGD-------QLAFKKSVDQMNAST", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . : . ::..:: : * : . :*:* : . .:.: *:: .*: : : * : * : : : .. . . : : * . . . .* : *:. ** .*:. *. .*. . : *. * :*:: ::: : ::: *. :: ::.::* **:*. .: :*.:* . .*:* :*: . :* ::: :*:*:: *::* : : : ::: : *: ::* . :* : : : : : :::: : *: : : :** *:: .*. . . * : : : ::*.. :: .:: . : .: : . : :: :: . :. * : : * . .: . . ::: :: .: :. : ..: : * . : . : * . : * . :.. : : : ::: ::::..:: *. * .: : . . : : :: : :. : . : . . . . : : . : .: . ", "identical_positions": 51, "similar_positions": 224, "identity": "4.64%" }, { "cls_id": "homologset.agr.SGD:S000005146", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2M4-1", "uniprot_id": "DECR2_RAT", "id": "Q9Z2M4-1", "name": "Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]", "aln": "--------MTQQP---------PDVEEDDCLSEYHHLFCPDLLQ--------------------------DKVAFITGGGSGIGFRIAEIFMRHGCHTVIVSRSLPRVSEAAKKLVAATGKR--CLPLS-MDVRVPPAVMAAVDQALKEFGKIDILINCAAGN-FLCPASALSFNAFKTVVDIDTLGTFNVSRVLYEKFFRDHGGVIVNITATLSMRGQVLQLHAGAAKAAVDAMTRHLAVEWGPQNIRVNSLAPGAISGTEGLRRLGGPKASSKFKYLSSPIPRLGTKTEIAHSVLYLASPLASYVSGIVLVVDGGSWMTLPNDIGRLL--EFESS-SAKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV68-1", "uniprot_id": "DECR2_MOUSE", "id": "Q9WV68-1", "name": "Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]", "aln": "--------MAQPP---------PDVEGDDCLPEYHHLFCPDLLQ--------------------------DKVAFITGGGSGIGFRIAEIFMRHGCHTVIVGRSLQKVTTAAKKLVAATGKR--CLPLS-MDVRVPPEVMTAVDQALQEFGKINILINCAAGN-FLCPASALSFNAFKTVVDIDTIGTFNVSSVLYKKFFRDHGGVIVNITATLSMRGQVLQLHAGAAKAAVDAMTRHLAVEWGPQNIRVNSLAPGAISGTEGLRRLRGSNASSKLKHFSNPIPRLGTKTEIAHSVLYLASPLASYVSGIVLVVDGGSWMTFPNGIKQLL--EFESF-SAKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NUI1-1", "uniprot_id": "DECR2_HUMAN", "id": "Q9NUI1-1", "name": "Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]", "aln": "--------MAQPP---------PDVEGDDCLPAYRHLFCPDLLR--------------------------DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRR--CLPLS-MDVRAPPAVMAAVDQALKEFGRIDILINCAAGN-FLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGGAWLTFPNGVKGLP--DFASF-SAKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NV34-1", "uniprot_id": "DECR2_DANRE", "id": "Q6NV34-1", "name": "Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]", "aln": "--------MAEKPQLVN--NLPEDVETDECMNKYTHIYSPDLLS--------------------------DQVAFITGGGSGIGFRIAEVLMRHGCDTVIASRNLEKISQAAKKLTSTTGRR--CLPIA-MDVRQPETILAAVDETLKTFGRVDILINNAAGN-FLCPATSLSFNAFKTVMEIDTMGTFNTSKVIYDKWFKDHGGSIVNISATLGYRGQALQVHAGSAKAANDAMTRHLAVEWGPSGVRVNTVAPGPISGTEGYRRLGGSHAETAGAFHSIPLQRAGNKTEMAHAVLFLASRASSYVTGSVLVADGGAWLTSANDVERLL--GIVSSRSAKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32573-1", "uniprot_id": "SPS19_YEAST", "id": "P32573-1", "name": "Peroxisomal 2,4-dienoyl-CoA reductase SPS19 [(3E)-enoyl-CoA-producing]", "aln": "--------MNTAN----------TLDG-KFVTEGS--WRPDLFK--------------------------GKVAFVTGGAGTICRVQTEALVLLGCKAAIVGRDQERTEQAAKGISQLAKDKDAVLAIANVDVRNFEQVENAVKKTVEKFGKIDFVIAGAAGN-FVCDFANLSPNAFKSVVDIDLLGSFNTAKACLKELKKSKG-SILFVSATFHYYGVPFQGHVGAAKAGIDALAKNLAVELGPLGIRSNCIAPGAIDNTEGLKRLAG-KKYKEKALAKIPLQRLGSTRDIAESTVYIFSPAASYVTGTVLVVDGGMWHLGTYFGHELYPEALIKSMTSKL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VRJ4-1", "uniprot_id": "Q9VRJ4_DROME", "id": "Q9VRJ4-1", "name": "", "aln": "MLHLSKQLVVRAPKIRLNASAVSGSGQSSSFDQNSNNYSRKLVGPNLNQCHKRLSSSSQSSTAGTMKRLAGKVAVVTASTDGIGFAIAKRLAEDGAAVVISSRKQKNVDSALAELRKLNLNV---HGLK-CHVSEPEDRKQLFEETISKFGKLNILVSNAATNPAVGGVLECDEKVWDKIFDVNVKSSYLLAKEALPLLRQQKNSSIVFVSSIAGYDAFELLGAYSVSKTALIGLTKAAAKDLAPEGIRVNCLAPGVIR-TKFSKALYENESANEAALSKIPMGRLGTSEEMAGVVSFLVSEDAGYITGESIVAGGG--------------------MTARL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : .*. .:**.:*.. . * :: : *. ..* .*. . * : : .* ..:::. **:::::: ** * : . :.:..:.::: .:: : :.:. *: ::: . : . :*:. .::: * : .* .:* * :*** * *: : * . *: * *.. ::* . :: * :.*::* :*..** :::*", "identical_positions": 38, "similar_positions": 97, "identity": "11.11%" }, { "cls_id": "homologset.agr.SGD:S000005148", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62848-1", "uniprot_id": "ARFG1_RAT", "id": "Q62848-1", "name": "ADP-ribosylation factor GTPase-activating protein 1", "aln": "------MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNAKFREFLEAQDDYEPSWSLQDKYSSRAAALFRDKVATLAEGKEWSLESSPAQNWTPPQPKTLQFTAHRPAGQPQNVTTSGDKAFEDWLNDDLGSYQG------------------------------AQENRYVGFGNT--VPPQKREDDFLNSAMSSLYSGWSSFTTGASKFASAAKEGATKFGSQASQKASE--LGHSLNENVLKPAQEKVKEG-RIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFS------------GKAEDTSDRPLEGHSYQNSSGDNSQNSTIDQSFWETFGSAEPPKAK-SPSSDSWTCADASTGRRSSDSWDIWGSGSASNNKNSN--------SDGWESWEGASGEGRAKATKKAAPSTAADEGWDNQNW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPJ9-1", "uniprot_id": "ARFG1_MOUSE", "id": "Q9EPJ9-1", "name": "ADP-ribosylation factor GTPase-activating protein 1", "aln": "------MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNAKFREFLETQDDYEPSWSLQDKYSSRAAALFRDKVATLAEGKEWSLESSPAQNWTPPQPKTLQFTAHRASGQPQSAAASGDKAFEDWLNDDLGSYQG------------------------------AQENRYVGFGNT--VPPQKREDDFLNNAMSSLYSGWSSFTTGASKFASAAKEGATKFGSQASQKASE--LGHSLNENVLKPAQEKVKEG-RIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFS------------GKAEDSSDRPLEGHSYQNSSGDNSQNSNIDQSFWETFGSAEPPKAK-SPSSDSWTCADASTGRRSSDSWDVWGSGSASNNKNSN--------SDGWESWEGASGEGRAKATKKAAPST-ADEGWDNQNW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N6T3-1", "uniprot_id": "ARFG1_HUMAN", "id": "Q8N6T3-1", "name": "ADP-ribosylation factor GTPase-activating protein 1", "aln": "------MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQG------------------------------AQGNRYVGFGNT--PPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKASE--LGHSLNENVLKPAQEKVKEG-KIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFS------------GKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWTCADTSTERRSSDSWEVWG--SASTNRNSN--------SDGGE-----GGEGTKKAVPPAVPTD---DGWDNQNW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VTX5-1", "uniprot_id": "Q9VTX5_DROME", "id": "Q9VTX5-1", "name": "ADP-ribosylation factor GTPase-activating protein 1", "aln": "------MASPRTRRVLQELKPQDENSKCFECGTHNPQWVSVTYGIWICLECSGKHRSLGVHLSFVRSVTMDKWKDIELEKMKAGGNRNAREFLEDQEDWNERAPITQRYNSKAAALYRDKIATLAQGKSWDLKEAQGRVGSNNSFSSGGSSNSSYQSRPSATGYGGNGGYQNGGGAEPGGYQQYQTQEFKDQKEEFFSRRQVENASRPENLPPSQGGKYAGFGFTREPPPKTQSQELFDSTLSTLASGWSLFSTNASKLASTAKEKAVTTVNLASTKIKEGTLLDSVQCGVTDVASKVTDMGKRGWNNLAG--SNISSPQGGYNDPNFEDSSAYQRSNSVGGNLAGGLGQQSGVSDSDWGGWQDNGNSKSHMTSSSSYHNQLSSSSGGGTASAGLTRDAD-WSGFEATNYQSSETSYQNASSGGSTARRNMKLQDTSQKLSEGFESLDVKSVKPKTATASSANKGTAEDDAWNLLMN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32572-1", "uniprot_id": "SPS18_YEAST", "id": "P32572-1", "name": "Sporulation protein SPS18", "aln": "MRLFENSKDMENRKRLLRAKKAAGNNNCFECKSVNPQFVSCSFGIFICVNCANLLRGMGTNIFCVKSITMDNFEEKDVRRVEKSGNNRFGSFLSKNGILQNGIPLREKYDNLFAKSYKRRLANEVRSNDINRN-----------------------------MYLGFNNFQQYTNG---------------------------------------------------ATSQIRDRTLREISNNSNASEGAEFVLPEKVLGSDNFQDCERFPACLSSERNLD--ENNVTSATSTLTIEKFQND---------PIGTISRSWQLLSDALYKSYEDFKG----------------SVVQPTIENIQQRNLPNDIKRSFVHFNEKLHETP---------HLPSPVFSCFTGGDILPPEFN-------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ..*: * . : *. **** : ***:** ::**:**::*:. *.:*.:: *:*:***:::: ::.::: .** . .**. : : .: ::*.. * :: ::. ..... . : . ::: . ..: :. : : : .: * : * . :.* : . * : . ..: . : : . . . :: .. :.. : . : . . .. . . :. : :: .. . ", "identical_positions": 34, "similar_positions": 113, "identity": "7.13%" }, { "cls_id": "homologset.agr.SGD:S000005151", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQS5-1", "uniprot_id": "RIOK2_MOUSE", "id": "Q9CQS5-1", "name": "Serine/threonine-protein kinase RIO2", "aln": "MGKVNVAKLRYMSRDDFRVLTAVEMGMKNHEIVPCSLIASIASLKH-GGCNKILRELVKHKLIAWERTKTVQGYRLTNAGYDYLALKTLSSRQVVESVGNQMGVGKESDIYIVANEAGQQLALKLHRLGRTSFRNLKNKRDYHKHRHN-VSWLYLSRLSAMKEFAYMKALYERKFPVPKPIDYNRHAVIMELINGYPLCQIHHVEDPASVYDEAMELIVKLGNHGLIHGDFNEFNLMLDK------DDHITMIDFPQMVSTSHPNAEWYFDRDVKCIREFFMKRFSYESELYPTFSDIRKEDSLDVEVSASGYTKEMQADDELLHPVGPDDKITETEEDSDFTFSDE--EMLEKAKVWRSELEKEAD-PADESGGSWCCSSTDSKQIKDGGLPEESAHVSS-FEVTALSQAVEEMERQVLPHRSVTEFSEESRRTEN-DGQPGQRS----PAGSEDCDDEPPHLIALSSVNREFRPFRDEESMSSVTRHRTRTLSVTSAGSALSCSTIPPELVKQKVKRQLTRQQKAAARRR-LQKGEANVFTKQRRENMQNIKSSLEAASFWGD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BVS4-1", "uniprot_id": "RIOK2_HUMAN", "id": "Q9BVS4-1", "name": "Serine/threonine-protein kinase RIO2", "aln": "MGKVNVAKLRYMSRDDFRVLTAVEMGMKNHEIVPGSLIASIASLKH-GGCNKVLRELVKHKLIAWERTKTVQGYRLTNAGYDYLALKTLSSRQVVESVGNQMGVGKESDIYIVANEEGQQFALKLHRLGRTSFRNLKNKRDYHKHRHN-VSWLYLSRLSAMKEFAYMKALYERKFPVPKPIDYNRHAVVMELINGYPLCQIHHVEDPASVYDEAMELIVKLANHGLIHGDFNEFNLILDE------SDHITMIDFPQMVSTSHPNAEWYFDRDVKCIKDFFMKRFSYESELFPTFKDIRREDTLDVEVSASGYTKEMQADDELLHPLGPDDKNIETKEGSEFSFSDG--EVAEKAEVYGSENESERN-CLEESEGCYCRSSGDPEQIKEDSLSEESADARS-FEMTEFNQALEEIKGQVVENNSVTEFSEEKNRTENYNRQDGQRVQGGVPAGSDEYEDECPHLIALSSLNREFRPFRDEENVGAMNQYRTRTLSITSSGSAVSCSTIPPELVKQKVKRQLTKQQKSAVRRR-LQKGEANIFTKQRRENMQNIKSSLEAASFWGE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VBU2-1", "uniprot_id": "Q9VBU2_DROME", "id": "Q9VBU2-1", "name": "Serine/threonine-protein kinase RIO2", "aln": "MGKLNVTVLRYLTKEDFRVLTAIEMGMKNHELVPGPLAAAIANLKS-GGVHKLLKELCKHKLLAYERGKKYDGYRLTNTGYDYLALKSLTLRGSVSSFGNQIGIGKESNIYVVADEEGTPICLKLHRLGRTCFRNVKAKRDYHGRRHK-ASWLYLSRISATREFAYMSALYDRGFPVPKPIDFNRHCVLMDLVKGWPMTQVHELLDAPQVYDDLMNLIVRLGNSGVIHGDFNEFNLMVTD------AGKPILIDFPQMMSTSHENAEFFFERDVNCVREMFRRKFGYESEDYPKFSDLVREDDLDAEVHCTGYGFTKEMEQDLLEEYGMVDQADEEDEGEDLEEEEEPPTLVTAASVEIDECRRQVENEVIYSEAKPTQKSDDAVRRYIESCTQYLGNLSVGPEVPDQTMPKKLDISLPAETPDVIPFEAETSATNTVEEDVKSIS------SNDLDTDEVPELVGLDPNSRMYRLKMVEQMLNDARSQRS---------YSTTTSTIAPSVITDRIRRNMDIKEKREQRKKCVAKGEASAVHRHRKENKDVVK-EYAGWDF---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40160-1", "uniprot_id": "RIO2_YEAST", "id": "P40160-1", "name": "Serine/threonine-protein kinase RIO2", "aln": "-MKLDTSHMRYLTTDDFRVLQAVEQGSRSHEVVPTPLIHQISGMRSQSGTNRAISDLAKLSLISKMRNVKYDGYRLTYNGIDYLALKTMLNRDTVYSVGNTIGVGKESDIYKVSDKNGNPRVMKIHRLGRTSFHSVRNNRDYLKKSNQGANWMHLSRLAANKEYQFMSMLYSKGFKVPEPFDNSRHIVVMELIEGYPMRRLRKHKNIPKLYSDLMCFIVDLANSGLIHCDFNEFNIMIKDKLEDENDCGFVVIDFPQCISIQHQDADYYFQRDVDCIRRFFKKKLKYEPK--------PDSSMLDTEGFGDGY---KYAYPDFKRDVKRTDNLDELVQASGFSKKHP--------------GDRGLETAVESMRNAVYNSDDD------------------------------MSNDEAEEENGEGDYSEED---EYYDSELDNES------SEDDSED-------------------------------------------------AQEEENERIIEALS-----------------SGVENLKMDKLGNYILE---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::.: :**:: :***** *:* * :.**:** .* *:.:: .* :: : :* * .*:: * . :***** * ******:: * * *.** :*:****:** *::: * :*:******.*:.:: :*** : :: ..*::***::* :*: :*. **.: * **:*:* .** *:*:*::*:*: :::. : ..:*.: * :** *.* *:** ******::: . :***** :* .* :*:::*:***.*:: :* ::: **.: .. **.* ** :: . *: * : . : .. : .. * . :. * : : : . ..: * . . .::: . : . . . : :: . ", "identical_positions": 121, "similar_positions": 142, "identity": "21.42%" }, { "cls_id": "homologset.agr.SGD:S000005153", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P11146-1", "uniprot_id": "HSP7B_DROME", "id": "P11146-1", "name": "Heat shock 70 kDa protein cognate 2", "aln": "--MGKIP-AIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTVFDAKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVYLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKN-LKGERNVLIFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRRLRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAKMDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSS-QIQDLLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNNLLGTFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLSEAEKYKVEDDRQRERVQSKNNLEAYIYACRQAVDD-APSGVLSETERSKVRDKCSSEASWLDKNSLAEKEEFESHLKECQRICTPIMSKIHGGKKGKSSMGKGSHPTVEEVDG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40150-1", "uniprot_id": "SSB2_YEAST", "id": "P40150-1", "name": "Ribosome-associated molecular chaperone SSB2", "aln": "MAEGVFQGAIGIDLGTTYSCVATYESS-VEIIANEQGNRVTPSFVAFTPQERLIGDAAKNQAALNPRNTVFDAKRLIGRRFDDESVQKDMKTWPFKVIDVDGNPVIEVQYLEETKTFSPQEISAMVLTKMKEIAEAKIGKKVEKAVITVPAYFNDAQRQATKDAGAISGLNVLRIINEPTAAAIAYGLGAGKSEKERHVLIFDLGGGTFDVSLLHIAGG-VYTVKSTSGNTHLGGQDFDTNLLEHFKAEFKKKTGLDISDDARALRRLRTAAERAKRTLSSVTQTTVEVDSLFDGEDFESSLTRARFEDLNAALFKSTLEPVEQVLKDAKISKSQIDEVVLVGGSTRIPKVQKLLSDFFDGKQLEKSINPDEAVAYGAAVQGAILTGQSTSDETKDLLLLDVAPLSLGVGMQGDIFGIVVPRNTTVPTIKRRTFTTVSDNQTTVQFPVYQGERVNCKENTLLGEFDLKNIPMMPAGEPVLEAIFEVDANGILKVTAVEKSTGKSSNITISNAVGRLSSEEIEKMVNQAEEFKAADEAFAKKHEARQRLESYVASIEQTVTDPVLSSKLKRGSKSKIEAALSDALAALQIEDPS-ADELRKAEVGLKRVVTKAMSSR-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : *************..::.* ******:****.***:***. ******.****.*:*.:************:***:.:*:*:* ******: .*:* ***:: * * *:*:***:******:****. :* **:.**:********:*********:*:***************:****. . : **:**************:* * * :: **:*:*:*****:***..*::** ***:* **..:**********.********* *::::*:*:*.:* ** *.::*****:** **:**::***:.*.***:.*. *.:************:****.*:*.****: ***************.***** .:* : :****:********: *.:: :* **: :* ::: *** ****.:* : **:***. *:*.*** *:*..** * * * :*. *:::*:***:*.* ::*****.:***** ****. **::*:.:**::*. *: :: ::::.**:*: : .*:* * . *. *.. .:**:. *. : *: :. : :*:.. :*: * **. ", "identical_positions": 349, "similar_positions": 168, "identity": "54.62%" }, { "cls_id": "homologset.agr.SGD:S000005157", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3T1H2-1", "uniprot_id": "NGRN_RAT", "id": "Q3T1H2-1", "name": "Neugrin", "aln": "--------MALSLSLFLGGRVRAAVAR-CGFASQGVAGPGSISREP-----DPDSDWEPEERELQEVESALKRQKKAMRFQKIRRQMEAPGAPPRTLTWEAMEQIRYLHKEFAESWSVPRLAEGFDVSTDVIRRVLKSKFIPTLEQKLKQDQKVLKK--------------------------AGITRVVWQLPVSEDTLKPLSAGHPMSGPLLMPGDEVSSNSQTHSRALKVKSNAP-SAEAQK---------KREEKNKRIRVLAESLVPTTTALGHQRELQKYTTH---DSEADRRANNHILPSVEKLEELEAGEPGDQNFSSKVVQKG-------REFFDSNGNFLYRI----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99KS2-1", "uniprot_id": "NGRN_MOUSE", "id": "Q99KS2-1", "name": "Neugrin", "aln": "--------MALSLSLFLGGRVRTSLAR-CGFASQVMAGPGSVSCEP-----DPDSDWEPEERELQEVESALKRQKKAMRFQKIRRQMEAPGAPPRTLTWEAMEQIRYLHKEFAESWSVPRLAEGFDVSTDVIRRVLKSKFVPTLEQKLRQDQKVLKK--------------------------AGFTREIGQLPVSEDTLKALSAGRSVSG-LLMAGDEVSSKSQNHSTALKVAKSHPHSTDAQK---------KREGRDKRIQVLEESLVPATTALGHQRELQKSATS---DSEATGRAGSDTLPSAVLLEELKPGEPGDQSFSSKVVQRG-------HDFFDSNGNFLYRI----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPE2-2", "uniprot_id": "NGRN_HUMAN", "id": "Q9NPE2-2", "name": "Neugrin", "aln": "--------MAVTLSLLLGGRVCAAVTR-CGFATRGVAGPGPIGREP-----DPDSDWEPEERELQEVESTLKRQKQAIRFQKIRRQMEAPGAPPRTLTWEAMEQIRYLHEEFPESWSVPRLAEGFDVSTDVIRRVLKSKFLPTLEQKLKQDQKVLKK--------------------------AGLAHSLQHLRGSGNTSKLLPAGHSVSGSLLMPGHEASSKDPNHSTALKVIESDTHRTNTPR---------RRKGRNKEIQDLEESFVPVAAPLGHPRELQKYSS----DSESPRGTGSGALPSGQKLEELKAEEP--DNFSSKVVQRG-------REFFDSNGNFLYRI----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40156-1", "uniprot_id": "RRG9_YEAST", "id": "P40156-1", "name": "Required for respiratory growth protein 9, mitochondrial", "aln": "-----MNILRIACRSFHCLRCGPLLNENRGWSSKKIIK--LVNKSS-----LSNKEFTEKVRDGTKDIPEWKKQKMAVR----KKLQGQRWNPPKKISQEQMEALRLLKFNFPE-LTASDLADRFKISPEAVRRILKSNWKRTDEENNNTYERWKRR--------------------------GERIKEMYQRKEDAD----FVSNQIVTSRKIILGSNSNSPELIARNVRTFKPFKPNNSTPEK---------KNTNKLYILKHLGSKQ---------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VBR0-1", "uniprot_id": "Q9VBR0_DROME", "id": "Q9VBR0-1", "name": "", "aln": "MTARMIQRGLHTARSCLLARAPRRANPGLGYQLEQLQEHPEKSSEASEDYADLESDFMDVQKTHRQYEREQQQHRDRIRQFMIKHKYFRDAKLPNLLLHAEKEQMRLLHERDPEEWSVERLAESFPATPDIVQKILRAKWRPRSVQRIRSHDETVIKNWQLLGTGKGDFSIPPSLLQHLQKFAERRWQDLRELKIQDWPTKSQLPTPQGNEFRKLLGSSSKTTEEMPTPQIPSGYEAPPSAAEDETYLLDKIRNKKKMRLQELKELQLVESAPAVPEEMKRPIENPSGTGFLPSFVPKFASSEIVISAADQRKYEITQVKTRIVIPRKLHRQGATYRVEDAYYDDDGELLYRVPGMTRASGDK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * *: . : . .. :.:: : : :::: :* :: *. : * :* *: . .* :. **: * :.: ::::*:::: :. . :. : : : . . . . : * . .: . . : . :. : :: * ", "identical_positions": 14, "similar_positions": 65, "identity": "3.86%" }, { "cls_id": "homologset.agr.SGD:S000005160", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5EAN7-1", "uniprot_id": "TE2IP_RAT", "id": "Q5EAN7-1", "name": "Telomeric repeat-binding factor 2-interacting protein 1", "aln": "----------------------------------------------------------------------------------------------------MAEVMDLGKDPNGPTHSSTLFVREDGSAMSFYVRPSSAKRR-------LSTLILHGGGILCRV---QKPGAVLLAQPG---------------------------------------------------------------------EALAEAS---GDFISTQYILDCVERNEKLELEAYRLG---LTEQASDPKPGASAEGSTEPEPQPLTGRIAYTDADDVAILTYVKE-NARSPSSVTGNALWKAMEKSSLTQHSWQSLKDRYLKHLQGQEHKYLLGNAPVS-------------------------------------------------------PSSQKLKRKAEQDPEAAD------------------------------------------------------------------------------------------------------SGEPQNKRTPD-------LPEEECVKGETKENGEADN---------------------------------------------------KLFEEATPELG-----EAVVDESP-DFEIHITMCDGDPPTPEED------------------SETQPDEEEEEP----------------------------KVSTQEVGTAIKIIRQLMEKFNLDLSTVTQALLKNSGELEATSSFLESGRRPDGF------PIWCRQDDLDLQKDDDDTRNALVKKYGAQNVARRIEFRKK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VL8-1", "uniprot_id": "TE2IP_MOUSE", "id": "Q91VL8-1", "name": "Telomeric repeat-binding factor 2-interacting protein 1", "aln": "----------------------------------------------------------------------------------------------------MAEAMDLGKDPNGPTHSSTLFVREDGSAMSFYVRPSSAKRR-------LSTLILHGGGTVCRV---QEPGAVLLAQPG---------------------------------------------------------------------EALAEAS---GDFISTQYILDCVDRNEKLDLEAYRLG---LTEQASDPKPGASTEGSTEPEPQPLTGRIAYTDAEDVAILTYVKE-NARSPSSVTGNALWKAMEKSSLTQHSWQSLKDRYLKHLRGQEHKYLLGNAPVS-------------------------------------------------------PSSQKLKRKAEQDPEAAD------------------------------------------------------------------------------------------------------SGEPQNKRAPD-------LPEEECVKGEIKENGEADN---------------------------------------------------KLFEEAAPEFG-----EAVVDESP-DFEIHITMCDGDPPTPEED------------------SETQPDEEEEEP----------------------------KVSTQEVGTAIKVIRQLMEKFNLDLSTVTQALLKNSGELEATSSFLESGRRPDGY------PIWCRQDDLDLQKDDDDTKNALVKKFGAQNVARRIEFRKK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYB0-1", "uniprot_id": "TE2IP_HUMAN", "id": "Q9NYB0-1", "name": "Telomeric repeat-binding factor 2-interacting protein 1", "aln": "----------------------------------------------------------------------------------------------------MAEAMDLGKDPNGPTHSSTLFVRDDGSSMSFYVRPSPAKRR-------LSTLILHGGGTVCRV---QEPGAVLLAQPG---------------------------------------------------------------------EALAEAS---GDFISTQYILDCVERNERLELEAYRLGPASAADTGSEAKPGALAEGAAEPEPQRHAGRIAFTDADDVAILTYVKE-NARSPSSVTGNALWKAMEKSSLTQHSWQSLKDRYLKHLRGQEHKYLLGDAPVS-------------------------------------------------------PSSQKLKRKAEEDPEAAD------------------------------------------------------------------------------------------------------SGEPQNKRTPD-------LPEEEYVKEEIQENEEAVK---------------------------------------------------KMLVEATREFE-----EVVVDESPPDFEIHITMCDDDPPTPEED------------------SETQPDEEEEEEE--------------------------EKVSQPEVGAAIKIIRQLMEKFNLDLSTVTQAFLKNSGELEATSAFLASGQRADGY------PIWSRQDDIDLQKDDEDTREALVKKFGAQNVARRIEFRKK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYJ3-1", "uniprot_id": "TE2IP_DANRE", "id": "Q6NYJ3-1", "name": "Telomeric repeat-binding factor 2-interacting protein 1", "aln": "----------------------------------------------------------------------------------------------------------MSKKKEASKISPVLFLDPGGQSMRFYVRPGPTKMQ-------LHPLITSGGGNLCRN---QEPGAILLIDPT---------------------------------------------------------------------DATNVTQNTGQKYISTKYILDCVEQNQQLDPNDYAIIIG-------------PSVQTRMALRNQGSGRLGYSSEEDAAILKFIEK-RQQD---AKGNLVWKEMEKRHVTEHSWQSMKDRFLKHLQQKLADKPTKKSPIKRKPLSFTQSPLRKKKVVEISEDESVQK-----------GDCPEAPMATETGSINPPASPERASSPPEEPQAAGQPSQASSNDSQDETCVLVIETPESENPRLDEDAPDASNEHSSLKKKRRKTCKTSTTDSRSSRLEEDPVGQDIPDESNAQSSPKKKRQKACKTS---------TTDSRSSRLEE-------NPDRRDIPDESTEQSSPNKSQMTSKISTSDSGNPIGDQGCDNPHGCNANSSPSKTRQTNSEASTPDSKKLGILAKAAKEFE-----DSDVMDDSEECENPCEVPIAEPSDAQESSATPATLVREPESQAEHHEETQPDSPMSEEERPGPSSAVVPPSLNSSTSCSHIRETPEETLSRDLLEVKEQVINLMRETKKDLVEVTKALLKASGDLKRAQVFLLNGYDHETHG-----PLWTRLDDETLLAADPYELEQLQSKFGEEEVTRRKSFLATDVK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P11938-1", "uniprot_id": "RAP1_YEAST", "id": "P11938-1", "name": "DNA-binding protein RAP1", "aln": "MSSPDDFETAPAEYVDALDPSMVVVDSGSAAVTAPSDSAAEVKANQNEENTGATAAETSEKVDQTEVEKKDDDDTTEVGVTTTTPSIADTAATANIASTSGASVTEPTTDDTAADEKKEQVSGPPLSNMKFYLNRDADAHDSLNDIDQLARLIRANGGEVLDSKPRESKENVFIVSPYNHTNLPTVTPTYIKACCQSNSLLNMENYLVPYDNFREVVDSRLQEESHSNGVDNSNSNSDNKDSIRPKTEIISTNTNGATEDSTSEKVMVDAEQQARLQEQAQLLRQHVSSTASITSGGHNDLVQIEQPQKDTSNNNNSNVNDEDNDLLTQDNNPQTADEGNASFQAQRSMISRGALPSHNKASFTDEEDEFILDVVRKNPTRRTTHTLYDEISHYVPNHTGNSIRHRFRVYLSKRLEYVYEVDKFGKLVRDDDGNLIKTKVLPPSIKRKFSADEDYTLAIAVKKQFYRDLFQIDPDTGRSLITDEDTPTAIARRNMTMDPNHVPGSEPNFAAYRTQSRRGPIAREFFKHFAEEHAAHTENAWRDRFRKFLLAYGIDDYISYYEAEKAQNREPEPMKNLTNRPKRPGVPTPGNYNSAAKRARNYSSQRNVQPTAN-------------AASANAAAAAAAAASNSYAIPENELLDEDTMNFISSLKNDLSNISNSLPFEYPHEIAEAIRSDFSNE---------------DIYDNIDPDTISFPPKIATTDLFLPLFFHFGSTRQFMDKLHEVISGDYEPSQAEKLVQDLCDETGIRKNFSTSILTCLSGDLMVFPRYFLNMFKDNVNPPPNVPGIWTHDDDESLKSNDQEQIRKLVKKHGTGRMEMRKRFFEKDLL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .. . . . * **:. .. * ** .** : :. ::: .* : . ::: :: .::: :*: : : . : .. . . :* :*. :: . . .. : . :.: :..*. *:.*. :.: . :. . *.* : .. :: * : ..* : *.. : : . . :: : : :: : ... * : . .:. .: :** : . : : :* : *. : **:* :: . : :* : ** * * . * .*.* .: * * . ", "identical_positions": 38, "similar_positions": 123, "identity": "4.44%" }, { "cls_id": "homologset.agr.SGD:S000005162", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CG07-1", "uniprot_id": "WRIP1_RAT", "id": "Q8CG07-1", "name": "ATPase WRNIP1", "aln": "MEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHPAGHAEPAAGPHRAGERAKGPSPPGAKRRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPARKGLGKRPAAAAAAGSASPRSWDETEAQEEEEAG--VDGDGDADVDGEDDPGHWDADAADAS--FGVSAG-RAHPRALPAEEIRQMLEGKPLADKMRPDTLQDYIGQSRAVGQET-LLRSLLETNEIPSLILWGPPGCGKTTLAHIIANNSKKHSIR--------FVTLSATNAKTNDVRDVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQDTFLPHVECGTITLIGATTENPSFQVNTALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSSRPTDPLSHSSNCSSEPSVFIEDKAVDTLAYLSDGDARTGLNGLQLAVLARLSSRKMFCKKSGQTYSPSRVLITENDVKEGLQRSHILYDRAGEEHYNCISALHKAMRGSDQNASLYWLARMLEGGEDPLYVARRLVRFASEDIGLADPSALAQAVAAYQGCHFIGMPECEVLLAQCVVYFARAPKSIEVYSAYNNVKACLRSHQGPLPP--VPLHLRNAPTRLMKDLGYGKGYKYNPMYSEP-VDQDYLPEELRG-------VDFFKQRRC--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XU0-1", "uniprot_id": "WRIP1_MOUSE", "id": "Q91XU0-1", "name": "ATPase WRNIP1", "aln": "MEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHPAGHAEPAAGSHRAGERAKGPSPPGAKRRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPARKGMGKRPAAAAAAGSASPRSWDEAEAQEEEEAG--VDGDGDADVDGEDDPGHWDADAADAS--FGVSAG-RAHPRALAAEEIRQMLEGKPLADKMRPDTLQDYIGQSRAVGQET-LLRSLLEANEIPSLILWGPPGCGKTTLAHIIANNSKKHSIR--------FVTLSATNAKTNDVRDVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQDTFLPHVECGTITLIGATTENPSFQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSSRPTDPLSHSSNCSSEPSVFIEDKAVDTLAYLSDGDARTGLNGLQLAVLARLSSRKVFCKKSGQTYSPSRVLITENDVKEGLQRSHILYDRAGEEHYNCISALHKAMRGSDQNASLYWLARMLEGGEDPLYVARRLVRFASEDIGLADPSALAQAVAAYQGCHFIGMPECEVLLAQCVVYFARAPKSIEVYSAYNNVKACLRSHQGPLPP--VPLHLRNAPTRLMKDLGYGKGYKYNPMYSEP-VDQDYLPEELRG-------VDFFKQRRC--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96S55-1", "uniprot_id": "WRIP1_HUMAN", "id": "Q96S55-1", "name": "ATPase WRNIP1", "aln": "MEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHPAGHAEPAAGSHRAGERAKGPSPPGAKRRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPGRKGSGKRPAAAAAAGSASPRSWDEAEAQEEEEAVGDGDGDGDADADGEDDPGHWDADAAEAATAFGASGGGRPHPRALAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAVGQDT-LLRSLLETNEIPSLILWGPPGCGKTTLAHIIASNSKKHSIR--------FVTLSATNAKTNDVRDVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQDTFLPHVECGTITLIGATTENPSFQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSSRPTDPLSHSSNSSSEPAMFIEDKAVDTLAYLSDGDARAGLNGLQLAVLARLSSRKMFCKKSGQSYSPSRVLITENDVKEGLQRSHILYDRAGEEHYNCISALHKSMRGSDQNASLYWLARMLEGGEDPLYVARRLVRFASEDIGLADPSALTQAVAAYQGCHFIGMPECEVLLAQCVVYFARAPKSIEVYSAYNNVKACLRNHQGPLPP--VPLHLRNAPTRLMKDLGYGKGYKYNPMYSEP-VDQEYLPEELRG-------VDFFKQRRC--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40151-1", "uniprot_id": "WRIP1_YEAST", "id": "P40151-1", "name": "DNA-dependent ATPase MGS1", "aln": "------MSNKRTSVEQLISCPICSRKVFFSLINSHLDICGKEK----SKPSSRPQTVSSLLAGP-----KKRKQANSEKFID---------LENKDHEIKPGLKSES----------------DDIEIVENESKRFKAAPSTDFAKSIVEPASSR----DQLHNDYESR------------------------------------------------WLQKISHLPLSEKLRPKELRDYVGQQHILSQDNGTLFKYIKQGTIPSMILWGPPGVGKTSLARLLTKTATTSSNESNVGSRYFMIETSATKANTQELRGIFEKSKKEYQLTKRRTVLFIDEIHRFNKVQQDLLLPHVENGDIILIGATTENPSFQLNNALISRCLIFVLEKLNVNELCIVLSRGIALLNKCRKQVWNIENPLKLSRS--------ILEYVVD----LSVGDTRRALN---MLEMIEVSTRERKADEEELSIDDVRDIIKNNSS-NGLN---TYYDPKGDNHYDTISAFHKSIRGGDENASLYYLARMLQGGEDPLYVARRMIRIASEDIGLRDSSLLPLAVAAHDAVMKVGLPEADLALAQCCVALARAPKSVELYRAWKKLRAMMSENMYSLASSEIPMHIRNAPTKLMEELGYHKGYKYNPDYIEGKVQQDYFPKEVLEKCPNKTDLKFLDGKHLGDKEDPDLRQSYQG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: * : :.**:*.: : : ****** * : ::*:: .: ... ** *:*: ::*. : : *.:..* . * ::** *: :....* *. . * : . .**.* : ::: *: * :. **::.:**. *:**.**.: :.*:. * . :: . ***:******* ***:**::::..:.. * . :: ***:*:*:::*.:::::::* .: **:*:*********** *** :***** * * ************:* **:*** ::***** *: : :* *.* *. : . :**. * . * : .** ** **:* .** : : .:*:*: ..:. : . * :*.:*. :**: ** *::**: ***:**::**.*:*****:*****:***********::*:******* *.* *. ****::. :*:**.:: **** * :******:*:* *:::::* : .: .*.. :*:*:*****:**::*** ******* * * *:*:*:*:*: :.*:. :: ", "identical_positions": 232, "similar_positions": 192, "identity": "33.24%" }, { "cls_id": "homologset.agr.SGD:S000005163", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LJG1-1", "uniprot_id": "A0ABK0LJG1_RAT", "id": "A0ABK0LJG1-1", "name": "Mannosyltransferase", "aln": "MCALEIAVREPEEAMVPRRLLLVGEGNFSFAASLIDGLDPDVSVTATGFQHRADLEGDPVALENLRRLRERGVEVRFGVDCTQLADEREFDRIYFNFPHCGRKAGVAKNRELLAKFFQSCADVLAKEGEVHVALCRGQGGTPADKPQREWHNSWQVVAMAALGGLILSDVCPFSCEAVPGYKCTGYRSQDRPFHIEGALTYIFTQSLPFESSRPRTFRVRLEDRWFYFTEPEALLGKLNRRFLEAPSCHPIRTINEKLIAELGKTFPLKRLRCPLPLLSQGGPSVLPPVACDLLPTFWICLHEDSSCSELLNGEITEDMEEIPDSGSECTLPKSPARDGCKAAQEGVCEQVKLRLRPSLLVHAEPVIHSPEFLPGSLYVLSGPVFRKCHILPFTMPAFHETLFILGFNRNTKESCLLPLLDHLKDTLGMASRRARQRLKGGGGG----GGGSGGGSGSGGDAGPAAEKLRELLGSREAG------------VEPRPE-SGNKAGQVWAPEGSTAFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGKGFQTWEYSPVYAIRSYAYLLLHAWPAAFHARILQTNKILVFYFLRCLLAFVSCVCELYFYKAVCKKFGLHVSRMMLAFLVLSTGMFCSSSAFLPSSFCMYTTLVAMTG-------WYMDKTPIAVLGVAAGAILGWPFSAALGLPIAFDLLAMKHRWKSF--FLWSLAALVLFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTS---HGPDLYGTEPWYFYLINGFLNFNVAFALALLVLPLTFLMEYLLQRFHVQN-LGHPYWLTLAPMYIWFMIFFIQPHKEERFLFPVYPLICLCGAVALSALQKCYH----FVFQRYRLEHYTVTSSWLALGTVFLFGLLSFSRSVALFRGYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWYRFPSSFLLP-DNWQLQFIPSEFRGQLPKPFAEGP---LATRIVPAHMNDQNREEPSRYIDISKCHYLVDVDTMRETPREPNYSSNREE-WVSLAHRPFLDASRSSKLLRAFYIP---------FLSDQYTVYVNYTILKPRKAKQSRKKSGG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDI9-1", "uniprot_id": "ALG9_MOUSE", "id": "Q8VDI9-1", "name": "Alpha-1,2-mannosyltransferase ALG9", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASRRARQRLKGGGGG----GGG-------GGDAGPAAEKL-EQLGSREAG------------AEPRPE-SGNKAGQVWAPEGSTAFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGKGFQTWEYSPVYAIRSYAYLLLHAWPAAFHARILQTNKILVFYFLRCLLAFVSCVCELYFYKAVCKKFGLHVSRMMLAFLVLSTGMFCSSSAFLPSSFCMYTTLIAMTG-------WYMDKTPIAVLGVAAGAILGWPFSAALGLPIAFDLLARKHRWKSF--LLWSLVALALFLVPVVVIDSYYYGKLVVAPLNIVLYNVFTS---HGPDLYGTEPWYFYLINGFLNFNVAFALALLVLPLTFLMEYLLQRFHVQN-LGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLICLCGAVALSALQKCYH----FVFQRYRLEHYTVTSNWLALGTVFLFGLLSFSRSVALFRGYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWYRFPSSFLLP-DNWQLQFIPSEFRGQLPKPFAEGP---LATRTVPTHMNDQNREEPSRYIDISKCHYLVDLDTMRETPREPNYSSHREE-WVSLAHRPFLDASRSSKLLRAFYVP---------FLSDQYTVYVNYTILKPRKAKPSRKKSGG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H6U8-1", "uniprot_id": "ALG9_HUMAN", "id": "Q9H6U8-1", "name": "Alpha-1,2-mannosyltransferase ALG9", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASRGARQRLKGSGAS----SGD----------TAPAADKLRELLGSREAGG-----------AEHRTELSGNKAGQVWAPEGSTAFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLSTGMFCSSSAFLPSSFCMYTTLIAMTG-------WYMDKTSIAVLGVAAGAILGWPFSAALGLPIAFDLLVMKHRWKSF--FHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTP---HGPDLYGTEPWYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQN-LGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLICLCGAVALSALQKCYH----FVFQRYRLEHYTVTSNWLALGTVFLFGLLSFSRSVALFRGYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWYRFPSSFLLP-DNWQLQFIPSEFRGQLPKPFAEGP---LATRIVPTDMNDQNLEEPSRYIDISKCHYLVDLDTMRETPREPKYSSNKEE-WISLAYRPFLDASRSSKLLRAFYVP---------FLSDQYTVYVNYTILKPRKAKQIRKKSGG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AZY9-1", "uniprot_id": "A0A8M3AZY9_DANRE", "id": "A0A8M3AZY9-1", "name": "Mannosyltransferase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATKSLRQRSRRGSKQ----DANNVNNTPTPENRATKDDKCAEDNKSSDPRNDLLPDKHISSCIPPLSYRSSGKAGQVWAPEGSTAFKCLVSARFCAALLSNLSDCDETFNYWEPTHYLLYGTGMQTWEYSPSYAIRSYAYLWLHALPACFHAKILQTNKVLVFYFLRCMLAFGCCVCELYFYKAVCKKFGLHVGRLLLAFLVLSAGMFCSSAAFLPSTFCMYSTVVAMTG-------WFQGRPSLAVLGVAAGAIVGWPFSALLGIPIAFDLLWLKKKWKSF--IMWTLVALLLFLVPVVIVDSYYYGKLVIAPLNIILYNVFTP---HGPDLYGTEPWHYYFVNGFLNFNIVFVLALFSLPLTALMEALLQRFNVQN-LGRPYWLTLSPMYLWMLVFFTRPHKEERFLFPIYPLICLCGAVALSSLQKCYH----FIFQRYRLEHYTISSNWLALGSVLLFGVLSLSRSVALFRGYHAPLDLYPEFHRIAKDPAIHTVPEGRLVNVCVGKEWYRFPSSFFLP-NNWHLQFIQSEFRGQLPKPYAMGP---DATWIIPPDMNDQNLEETSRYVDLKQCHYLVDLATETEAPREPRYATNKEE-WSVIADKPFLDSTRSSRILRAFFIP---------FLSEQYNTYSRYVILKPRRPKHTRKRPQA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBV8-1", "uniprot_id": "ALG9_DROME", "id": "Q9VBV8-1", "name": "Alpha-1,2-mannosyltransferase Alg9", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPPAARARYIANKADNQILSKKPPKRPGLNGNNKTKEATPAGKKKDKDAKKR----------NQPTSGGQEKGLPNPIMPSVQTAFKTFVSARLCSAIWAYIADCDETFNYWEPLHYIINGHGLQTWEYSPQFGLRSYTYLLLQGVPGYFYQKLFNPSPILIFYMVRCMLGFGCAVMERYMYKSICQEFGIHIGRLWLIFQLFSVGMFVSSTALLPSSFSMYFGCAALAA-------WWQQNYCFAIFLTAISALLGWPFAALIGIPLVLEMLLRQRDWKTF--VQWTLISGATVAIPMIAIDTSYFGKLTFAPLNIVWYNVFTS---HGPNIFGTEPLSYYIINGFLNFNIIWLLALQ-LPIMLVIDYLIVPAKSKSTLNFPHYISLAPLYLWLLVFFAQPHKEERFLFPIYPLISLCGAITVDVYQRIFFRMKSVVFKIKAGVHYLDHSMFIAILVMVTSTLLGLSRVFALYRNYHAPMDLMLELNQFKATP---QYDPDVIYNVCIGKDWHRYPGSFFFPAKNFRLRFLKSEFRGMLPAYYDEGQ---NATKVVQPYFNDLNQENEHMYFDYDRCDFLVDFDEGKYTALEPNYSKRSKD-WSVMKSLPFLIPEKSHKVLRAFYVP---------FLTDNHIQYGDFNLLKRKTKRNGR-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53868-1", "uniprot_id": "ALG9_YEAST", "id": "P53868-1", "name": "Alpha-1,2-mannosyltransferase ALG9", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNCKAVTISLLLLLFLTRVYIQPTFSLISDCDETFNYWEPLNLLVRGFGKQTWEYSPEYSIRSWAFLLPFYCILYPVNKFTDLESHWNFFITRACLGFFSFIMEFKLHREIAGSLALQIANIWIIFQLFNPGWFHASVELLPSAVAMLLYVGATRHSLRYLSTGSTSNFTKSLAYNFLASILGWPFVLILSLPLCLHYLFNHRIISTIRTAFDCCLIFSLTAFAVIVTDSIFYGKLAPVSWNILFYNVINASEESGPNIFGVEPWYYYPLNLLLNF-----------PLPVLVLAILGIFHLRL------WPLWASLFTWIAVFTQQPHKEERFLYPIYGLITLSASIAFYKVLNLFN-------------RKPILKKGIKLSVLLIVAGQAMSRIVALVNNYTAPIAVYEQFSSLNQGG-----VKAPVVNVCTGREWYHFPSSFLLP-DNHRLKFVKSGFDGLLPGDFPESGSIFKKIRTLPKGMNNKNIYDTGKEWPITRCDYFIDIVAPINLTKDVFNPLHLMDNWNKLACAAFIDGENSKILGRAFYVPEPINRIMQIVLPKQWNQVYGVRYIDYCLFEKPTETTN-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : ::: . : ::*********** : :: * * ******* :.:**:::* :: : . *:: *. *.* . : * ::: :. .:.:::..: : * ::. * * :* :***:..* * . :: .:::**** :.:*: :. * :: .:: ..:: *: ::***. .. **: ***:.. **:::*.** :* :* :*** *: :: :: : : : :.:: *: :* :********:*:* ** *..:::. . : : . : : :. .:** .** ..* .*: : :: : *** *::*:::*.**::* .* :*:*: * * * ** : . : :*: * : :*.:::*. . : . . : * : .*: .* : ***::* .*..: :. . ", "identical_positions": 113, "similar_positions": 176, "identity": "10.32%" }, { "cls_id": "homologset.agr.SGD:S000005164", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AEP0-1", "uniprot_id": "D4AEP0_RAT", "id": "D4AEP0-1", "name": "Adenylosuccinate synthetase isozyme 2", "aln": "MS---ISESSPAATSLPNGDCGRPRA---------RPGGNRVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGLDGWEKRLIISDRAHIVFDFHQAADGIQEQQRQ--EQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSD----FDGFSERFKVLANQYKSIYPTLEIDIEGELQQLKGYMERIKPMVRDGVYFLYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVLLKYAHMINGFTALALTKLDILDMFTEIKVGVAYK-LDGETIPHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKELPVNAQNYVRFIEDELQIPVKWIGVGKSRESMIQLF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P46664-1", "uniprot_id": "PURA2_MOUSE", "id": "P46664-1", "name": "Adenylosuccinate synthetase isozyme 2", "aln": "MS---ISESSPAATSLPNGDCGRPRA---------RSGGNRVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGLDGWEKRLIISDRAHIVFDFHQAADGIQEQQRQ--EQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSD----FDGFSERFKVLANQYKSIYPTLEIDIEGELQQLKGYMERIKPMVKDGVYFLYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVSLKYAHMINGFTALALTKLDILDMFTEIKVGVAYK-LDGETIPHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKELPVNAQNYVRFIEDELQIPVKWIGVGKSRESMIQLF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30520-1", "uniprot_id": "PURA2_HUMAN", "id": "P30520-1", "name": "Adenylosuccinate synthetase isozyme 2", "aln": "MA---FAETYPAASSLPNGDCGRPRA---------RPGGNRVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGLEGWEKRLIISDRAHIVFDFHQAADGIQEQQRQ--EQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSD----FDGFSERFKVLANQYKSIYPTLEIDIEGELQKLKGYMEKIKPMVRDGVYFLYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVLLKYAHMINGFTALALTKLDILDMFTEIKVGVAYK-LDGEIIPHIPANQEVLNKVEVQYKTLPGWNTDISNARAFKELPVNAQNYVRFIEDELQIPVKWIGVGKSRESMIQLF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q568F6-1", "uniprot_id": "PURA2_DANRE", "id": "Q568F6-1", "name": "Adenylosuccinate synthetase isozyme 2", "aln": "MS---DSGDAQPQDGG-NSSSSRGKS---------PSVGNRVTVVLGAQWGDEGKGKVVDLLAQDADMVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPKVTAFIGNGVVIHLPGLFEEAEKNVRKGKGLEGWESRLIISDRAHIVFDFHQAVDGVQEQERQ--QQAGKNLGTTKKGIGPVYSAKAARSGLRICDLLAD----FQEFSERFKHLASQYKSMYPSLEIDVDGELEKLKSYVDRIKPMVRDGVFFMYEALHGDPKRILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQSNETGELLQTRGKEVGVTTGRKRRCGWLDLVLIKYAHMINGFTALALTKLDILDVLPEIKVGVAYK-VNGETIPHFPANQEVLQKVEVEYETLPGWSTDTSAVRTFEELPENAKKYVCFIEDRLGVPVKWIGVGKSRESMIQLF--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P28650-1", "uniprot_id": "PURA1_MOUSE", "id": "P28650-1", "name": "Adenylosuccinate synthetase isozyme 1", "aln": "MSGTRASNDRPPGTGGVKRGRLQQEA---------AATGSRVTVVLGAQWGDEGKGKVVDLLATDADIVSRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKG--LKDWEKRLIISDRAHLVFDFHQAVDGLQEVQRQ--AQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSD----FDEFSARFKNLAHQHQSMFPTLEIDVEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPPKKVLVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGDLLQNRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTKLDILDVLSEIKVGISYK-LNGKRIPYFPANQEILQKVEVEYETLPGWKADTTGARKWEDLPPQAQSYVRFVENHMGVAVKWVGVGKSRESMIQLF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R629-1", "uniprot_id": "M0R629_RAT", "id": "M0R629-1", "name": "Adenylosuccinate synthetase isozyme 1", "aln": "MSGTRASNDRPPGTGGVKRGRLQQEA---------AATGSRVTVVLGAQWGDEGKGKVVDLLATDADIVSRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKG--LKDWEKRLIISDRAHLVFDFHQAVDGLQEVQRQ--AQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSD----FDEFSARFKNLAHQHQSMFPTLEIDVEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGDLLQNRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTKLDILDVLSEIKVGISYK-LNGKRIPYFPANQEILQKVEVEYETLPGWKADTTGARKWEDLPPQAQSYVRFVENHLGVAVKWVGVGKSRESMIQLF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N142-1", "uniprot_id": "PURA1_HUMAN", "id": "Q8N142-1", "name": "Adenylosuccinate synthetase isozyme 1", "aln": "MSGTRASNDRPPGAGGVKRGRLQQEA---------AATGSRVTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKG--LKDWEKRLIISDRAHLVFDFHQAVDGLQEVQRQ--AQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSD----FDEFSSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTKLDILDVLGEVKVGVSYK-LNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQNYIRFVENHVGVAVKWVGVGKSRESMIQLF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NSN5-1", "uniprot_id": "PURA1_DANRE", "id": "Q6NSN5-1", "name": "Adenylosuccinate synthetase isozyme 1", "aln": "MSSGWSQNDHRSYSNPPPVS-GKRPR---------NDSGNKVTVVLGAQWGDEGKGKVVDLLATESDIVGRCQGGNNAGHTVVVEEKEYDFHLLPSGIINTKCTSFIGNGVVIHLPGLFEEIDKNEKKG--LKGWEKRLVISDRAHIVFDFHQAVDGLQETQRQ--AQEGKNIGTTKKGIGPTYACKASRTGLRICDLMAD----FNEFSTRVKNLVQQYQSMYPTLKVDVESELKKLKEYAERIRPLVRDGVYFMYDAIHGPQKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPANIGDVYGVSKAYTTRVGIGAFPTEQLNAVGELLQTRGHEVGVTTGRKRRCGWLDLVILKYAHMINGFTAIALTKLDILDVLDEIKVGVAYK-INGKRIPHFPANLEVLQKVEVEYETFPGWKSDTSAARKWGDLPAKAQNYIRFVENHIGVPIKWVGVGKSRECMIQMF--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1P7Y0-1", "uniprot_id": "A0A8M1P7Y0_DANRE", "id": "A0A8M1P7Y0-1", "name": "Adenylosuccinate synthetase", "aln": "MAADSTMSNGQETACLNGEPALKRSRDSLDSLRVPREPQNKVTVVLGAQWGDEGKGKVVDLLAMDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGVLNKKATSFIGNGVVIHLPGLFDEAEKNLQKGNGLQGWEERLKISDRAHIVFNFHQAVDGIQEQLRQ--QQAGKNLGTTKKGIGPAYSSKAARNGLRVCDLVSD----FSVFEEKFRVLAGHYQTTYPNLNIDIDAELQQLKNFAERLRPLVTDGVYFMHKALTGPSKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGVPPSHVGRVYGVVKAYTTRVGVGAFPTEQNNEIGDLLQSRGREFGVTTGRRRRCGWLDLVLVRYAHMVNGFSAIALTKLDILDTLPEIKIGTAYT-VDGKPLPSFPANMDVLTKVQVTYETFPGWSCSTEGVRSFDELPTQAQSYIKFIEDFLQVPVKWVGVGKSRESMIKLF--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y0Y2-1", "uniprot_id": "PURA_DROME", "id": "Q9Y0Y2-1", "name": "Adenylosuccinate synthetase", "aln": "MS--------ASATNGTHYEQLHQGR--------TKMYKSKVDVVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCVSVIGNGVVIHLPSLFDEVLKNEAKG--LQHLENRLIISDRAHLVFDFHQHVDGMQEAEK-----GGKSLGTTKKGIGPAYSSKATRNGIRVGELLGD----FNLFSEKFKSIVATHVRLFPSINVDVEAELARYKDYADKVRPYVKDTICFLHTALRN-GKTILVEGANAAMLDIDFGTYPYVTSSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSLVNGYTCICLTKLDILDTLPEIKVAVAYKKPNGEKLDHFPGTIAELGNIEVEYAVLPGWQTSTEEVRNFKELPENAQSYVRLLESELSVPVRWVGVGKGRESIINVH--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P80210-1", "uniprot_id": "PURA_YEAST", "id": "P80210-1", "name": "Adenylosuccinate synthetase", "aln": "----------------------------------------MVNVVLGSQWGDEGKGKLVDLLVGKYDIVARCAGGNNAGHTIVVDGVKYDFHMLPSGLVNPNCQNLLGNGVVIHVPSFFKELETLEAKG--LKNARSRLFVSSRAHLVFDFHQVTDKLRELELSGRSKDGKNIGTTGKGIGPTYSTKASRSGLRVHHLVNDQPGAWEEFVARYKRLLETRRQRYGDFEYDFEAKLAEYKKLREQLKPFVVDSVVFMHNAIEA-KKKILVEGANALMLDIDFGTYPYVTSSNTGIGGVLTGLGIPPRTIDEIYGVVKAYTTRVGEGPFPTEQLNENGEKLQTIGAEFGVTTGRKRRCGWLDLVVLKYSTLINGYTSLNITKLDVLDTFKEIPVGISYS-IQGKKLDLFPEDLNILGKVEVEYKVLPGWDQDITKITKYEDLPENAKKYLKYIEDFVGVPVEWVGTGPARESMLHKEIK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ****:*********:**:*. . *:: ** ********:*.: ::***:****::* : .:*******:*.:*.* . ** *. ..** :*.***:**:*** .* ::* **.:*** *****.*: **:*.*:*: .*: * :. * : : : : :: *.:.:* . * ::::* * * : *:: *: * :******* :*********:***** :*** ****:** :. : ** ******** *.***** * * **. * * **** *:*******: ::*: ::**::.: :****:** : *: :. :*. :*: : :* * :::* * .:***. . : :** :*:.*: :*. : :.:.*:*.* .**.::: ", "identical_positions": 184, "similar_positions": 124, "identity": "38.57%" }, { "cls_id": "homologset.agr.SGD:S000005165", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AE75-1", "uniprot_id": "D4AE75_RAT", "id": "D4AE75-1", "name": "", "aln": "MSNAKERKHAKKMRSQPSNVTLSSGFVTERDGKRHFGG-KPSQSQKQELHSGTSRQWQIKMSPHLLPESDANEQTSSKTMFKKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQKS--SNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEMAKKEAEKAAHQKKEHSKNKCHKARRCHINRTLEFNRRQQKNIWLETHIWHAKRFHMVKRWGYCLGERPTAKSHRACYRAMTDL-----CLLQDLSYYCCLELKGKEEEILKALSQMCSIDTGLTFAAVHCLSGKRQGSLMLYRANKYPRDMLGPVTFIWKSRETPGDASEE-RQLWIWLHPTLKLAVLEEIKTTCQCSEPVKPSVCVPAPLLTPAQEDIQAGLADDKIGKKRKRRDDGENARRAKKTIGDGTGDPCQPRSWLSPTTGIVVSDLTMEMNRFRLVGPLSHCILTSALRAAPVHRGEEDAEETPHGWWTDTCRSPHGLSLHQRQEAVFQLLGGISSPAEIPAGTILGLTVRDPRVNLPPQRCRALPDPERYHVSEFICEEGMCTSSWSCAHWKPLSDHTDDPDNEQVKQLLLEGVPVECAHSFIWNQDICQSVTENKIVDQDLNRMRS-ELLVPGSQLVLGARESKIPILLIQQPG-KVTGEDRLGWGSGWDILLPKGWGMAFWIPFIYRG-ARVGGLKEAAVHSQYKRSPNVPGDFPDCRAG-VLFAEDQAKDLLEKYQRRPPAKRPNYVKLGTLAPFCCP-WEQLTRDWESRIQTQEAAVIDSVPGAQETDPRRLGVPCV--PKETCQLSNEASIAENQPRKPEVT---GCQAQAGTEVALEQNASEDHAAATGSQLCVVRSRKLLKQLSSWCGPSSE----VRRAPCRGQQELTRKACLSILADFPRALVWVSLSLLKKGSPEPHTMICVPSKEDLFQLSQDQCYHGPCESRHSDPFKSLILKEKEKKKKEKRQDGEQGASKGQAAGAPTAGQEARIQGLWSGPLP-----GLTSHCSRPLLGFVTHGDFSMAVGCGEALGFVSVTGLLEMLSSQSAAMRG------LVLLRPPTSLQYRFARVTIEV-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99575-1", "uniprot_id": "POP1_HUMAN", "id": "Q99575-1", "name": "Ribonucleases P/MRP protein subunit POP1", "aln": "MSNAKERKHAKKMRNQPTNVTLSSGFVADRGVKHHSGGEKPFQAQKQEPHPGTSRQRQTRVNPHSLPDPEVNEQSSSKGMFRKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQKS--SNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEIAQKEAEKAVHQKKEHSKNKCHKARRCHMNRTLEFNRRQKKNIWLETHIWHAKRFHMVKKWGYCLGERPTVKSHRACYRAMTNR-----CLLQDLSYYCCLELKGKEEEILKALSGMCNIDTGLTFAAVHCLSGKRQGSLVLYRVNKYPREMLGPVTFIWKSQRTPGDPSES-RQLWIWLHPTLKQDILEEIKAACQCVEPIKSAVCIADPLPTPSQEKSQTELPDEKIGKKRKRKDDGENAKPIKKIIGDGTRDPCLPYSWISPTTGIIISDLTMEMNRFRLIGPLSHSILTEAIKAASVHTVGEDTEETPHRWWIETCKKPDSVSLHCRQEAIFELLGGITSPAEIPAGTILGLTVGDPRINLPQKKSKALPNPEKCQD------------------------------NEKVRQLLLEGVPVECTHSFIWNQDICKSVTENKISDQDLNRMRS-ELLVPGSQLILGPHESKIPILLIQQPG-KVTGEDRLGWGSGWDVLLPKGWGMAFWIPFIYRG-VRVGGLKESAVHSQYKRSPNVPGDFPDCPAG-MLFAEEQAKNLLEKYKRRPPAKRPNYVKLGTLAPFCCP-WEQLTQDWESRVQAYEEPSVASSPNGKESDLRRSEVPCAPMPKKTHQPSDEVGTSIEHPREAEEVMDAGCQESAGPERITDQEASENHVAATGSHLCVLRSRKLLKQLSAWCGPSSEDSRGGRRAPGRGQQGLTREACLSILGHFPRALVWVSLSLLSKGSPEPHTMICVPAKEDFLQLHEDWHYCGPQESKHSDPFRSKILKQKEKKKREKRQKPGRASSDGPAGEEPVAGQEALTLGLWSGPLP-----RVTLHCSRTLLGFVTQGDFSMAVGCGEALGFVSLTGLLDMLSSQPAAQRG------LVLLRPPASLQYRFARIAIEV-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KVW2-1", "uniprot_id": "Q7KVW2_DROME", "id": "Q7KVW2-1", "name": "", "aln": "-------------------------------------------------------------------------------MSTQKVEYDAALGGR-VTLPSHVTTYHYAAEALQEIRNLVADCQETTQRSSKLIFQTLPKHMRRRAMSHHPKRLPRKYRQAHKSQMGKSGNQP-VNGKRPSRKYRRRPKNLMREYVRRQRRHVWLETHIWHAKRFHMVDRWGHRLPYASCDKTYRACYRASAEH-----CLLQDISFYGCVELRGPLDMLREGFARLTSPQCGLGITARTFLSGRREGSVELFEDGRYPYGALQRASFMWRPRREEEDEKQTNHTLWLWLHPSGAQAVLNQLISVFQLKSTRQQKLPLNEAVTEEKMDVDKIEPVELSKETSPGKKNSKKKPEQRPLRFWTKTKAFDPQPSYFNSDGTLHLVLLQREFNRFRLTGPRAQKVLFASLR-------------------------PHREEELQDKANYCQAALQLSSPAELLSNLVMAHLVVDPRLQRPKKRTKAVGKMEQPPLS---------------------------------AGDLLMNQPKSLPESPLWSKKARERLAKGIMSAHKYDQLREQHAVVPGAPCAFEQQMQALPVILIQRPGSQDPRYKRLGYGCGWDVIAPAGYGMTLWLTLTMWG-ARPGGLRELDS---VAREAGAEIHLPDTLAG-VQRAAASADELRARYFRMPPNKRTNYRKLAVVSPFTAP-WRHLVRDWRASFSSASE---------------------------------------------------------------------------GSSFYVLRHRQQLEEIVESIRHRSP---LPQTLPDDAIIQIQLQLLSRGHVKDNALICLPTAADHKKRWRQLKHNDQAPVHVEPTQPDLNEQLRKELRQSHKLKLKRLRSRRVREKRRLQETATKRVHIRPANTAHLVRGQLQEMCRLWLPTDPAELRDSVRRQCSRQVFGYVSTAGFSFTEALVCAVGYVTPAGLQQLIEELPASKGNRKQPPLMCLVRDADSRDYRWASFQVNLNVASPTF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41812-1", "uniprot_id": "POP1_YEAST", "id": "P41812-1", "name": "Ribonucleases P/MRP protein subunit POP1", "aln": "---------------------------------------------MSGSLSRGNGGKKVLNKNQLLKRNRIRNARSIRAEAVAASSTKTGTPSDLSESGSKLNVDQFISSRQFEVKQLQLAMHNSKAASSTRIFQALPRKLRRRTASHNVRRIPKRMRNRALREMRKSDQQDVLKGSSASSRKAHGLNAKQLYKARMSIKLLRLASKSTSMKLSMPPEVTSSNCHVRQKIKTLKRMIKESSTANPNIKLLNNRMGSYDCTGVN-ELAPIPKGRVKYTKRQKHFAWLPTHIWNAKRSHMMKRWG---YQMVWAPTQKCFKLTHRLGGDTCSSDGALCMDSSYIGTIIVKDKSNDSEGDFLKSIIGKLTAERANLRKYREGQVLFQGLIYSFNEENGEDSTKPLGPCDVFWVQKDTAIIR---LHPSIYTQVFNILLQHKEKLTVQDCRYSLASVTLKG---------------AKALESLASCLRSTEYSKSFEQFKMVSMITDHNALPQRCTFAFEAIDPRHLAAPKKLNDSQRKTVNSDD---------------------------------ILSLHENYPQDEINAVFNELCDPESRTQSYNNQNTLKEISARRYKLLTATPNSIN-KTTVPFKESDDPSIPLVIIRRLKT-RDWIVVLPWFWLLPLWHLLNRIPRMYHIGLRQFQQIQYENKQLYFPDDYPFTQLGYIENSFYKKEASKTKWDRKPMGKRINFEKIKDIHNTKLPAYSGEIGDFFSSDWRFLQILR------------------------------------------------------------------------NGIDYLQRNDKTLELMDSKKTGQFN----AQGVRDINCVNDVLEFCKDYEAKTKAMSLSIEENIPVALCKNRKCQFRTPDSISVNSSSFSLTFFPRCIIAVSCTLLERGHPKDNARIYQVPEKDLEHWLQLAKGVYRPNGRKDHDLKIPLPEVH-------------DLIGFITSGTYHLNCGNGMGIGFIDHHAAIRQPTR-------------YVLIRNVGTNTYRLGEWSKISV------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:. . . :.. : *: : :.. *.. :**:**:::***: **: :*:*:: :: : *: :* :.. . : : * . : : * :: * . . *: : : : * : :. * * :. : :. . : : . ..:*. : : * . : .:. * . * : : :: : . . :. :. : . : . : : : :. : ::: . : ::. : :. . *** . :: . * . * . .: : . : ::. : ..: . : : :*. : *. ** .* :: * : :.:* : **:: :. . * * : : . . :: * * ** *: *: : * : *: : .. : * : *: : : : . : : .* . . . . : . . : . *: : ::*::: . : : . .:*:: . *:* : ** . ", "identical_positions": 60, "similar_positions": 196, "identity": "5.53%" }, { "cls_id": "homologset.agr.SGD:S000005166", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KLK9-1", "uniprot_id": "SSU72_RAT", "id": "Q4KLK9-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "aln": "MP---SSPLRVAVVCSSNQNRSMEAHNILSKRGFSVRSFGTGTHVKLPGPAPDKPNVYDFKTTYDQMYNDLLRKDKELYTQNGILHMLDRNKRIKPRPERFQNCKDLFDLILTCEERVYDQVVEDLNSREQETCQPVHVVNVDIQDNHEEATLGAFLICELCQCIQ------HTEDM--ENEIDELLQEFEE-KSGRAFLHTVCFY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NP77-1", "uniprot_id": "SSU72_HUMAN", "id": "Q9NP77-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "aln": "MP---SSPLRVAVVCSSNQNRSMEAHNILSKRGFSVRSFGTGTHVKLPGPAPDKPNVYDFKTTYDQMYNDLLRKDKELYTQNGILHMLDRNKRIKPRPERFQNCKDLFDLILTCEERVYDQVVEDLNSREQETCQPVHVVNVDIQDNHEEATLGAFLICELCQCIQ------HTEDM--ENEIDELLQEFEE-KSGRTFLHTVCFY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CY97-1", "uniprot_id": "SSU72_MOUSE", "id": "Q9CY97-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "aln": "MP---SSPLRVAVVCSSNQNRSMEAHNILSKRGFSVRSFGTGTHVKLPGPAPDKPNVYDFKTTYDQMYNDLLRKDKELYTQNGILHMLDRNKRIKPRPERFQNCTDLFDLILTCEERVYDQVVEDLNSREQETCQPVHVVNVDIQDNHEEATLGAFLICELCQCIQ------HTEDM--ENEIDELLQEFEE-KSGRAFLHTVCFY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PC19-1", "uniprot_id": "SSU72_DANRE", "id": "Q6PC19-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "aln": "MP---PHPLRVAVVCSSNQNRSMEAHNILSKRGFDVRSFGTGTHVKLPGPAPDKPNIYDFKTTYEQMYNDLVRKDKELYTQNGILHMLDRNKRIKSRPERFQSCRDQFDLVITCEERVYDQVLEDLNSREQESFQPVHVINVDIQDNHEEATLGAFLICELCQCIQ------HTDDM--ENEMDELLQEFEE-KSHRPFLHSVCFY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A1W2PQ27-1", "uniprot_id": "S72L1_HUMAN", "id": "A0A1W2PQ27-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72 like protein 1", "aln": "ML---SSTLRVAVVCVSNVNRSMEAHSILRRKGLSVRSFGTESHVRLPGPRPNRPVVYDFATTYKEMYNDLLRKDRERYTRNGILHILGRNERIKPGPERFQECTDFFDVIFTCEESVYDTVVEDLCSREQQTFQPVHVINMEIQDTLEDATLGAFLICEICQCLQ------QSDDM--EDNLEELLLQMEE-KAGKSFLHTVCFY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1W2PQD8-1", "uniprot_id": "S72L2_HUMAN", "id": "A0A1W2PQD8-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72 like protein 2", "aln": "ML---SSTLRVAVVCVSNVNRSMEAHSILRKKGLSVRSFGTESHVRLPGPRPNRPVVYDFATTYKEMYNDLLRKDRECYTRNGILHILGRNERIKPGPERFQECTDFFDVIFTCEESVYDTVVEDLCSREQQTFQPVHVINMEIQDTLEDATLGAFLICEICQCLQ------QSDDM--EDNLEELLLQMEE-KAGKSFLHTVCFY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1W2PQ64-1", "uniprot_id": "S72L5_HUMAN", "id": "A0A1W2PQ64-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72 like protein 5", "aln": "ML---SSTLRVAVVCVSNVNRSMEAHSILRRKGLSVRSFGTESHVRLPGPRPNRPVVYDFATTYKEMYNDLLRKDRERYTRNGILHILGRNERIKPGPERFQECTDSFDVIFTCEESVYDTVVEDLCSREQQTFQPVHVINMEIQDTLEDATLGAFLICEICQCLQ------QSDDM--EDNLEELLLQMEE-KAGKSFLHTVCFY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1W2PQC6-1", "uniprot_id": "S72L4_HUMAN", "id": "A0A1W2PQC6-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72 like protein 4", "aln": "ML---SSTLRVAVVCVSNVNRSMEAHSILRRKGLSVRSFGTESHVRLPGPRPNRPVVYDFATTYKEMYNDLLRKDRERYTRNGILHILGRNERIKPGPERFQECTDFFDVIFTCEESVYDTVVEDLCSREQQTFQPVHVINMDIQDTLEDATLGAFLICEICQCLQ------QSDDM--EDNLEELLLQMEE-KAGKSFLHTVCFY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1W2PQJ5-1", "uniprot_id": "S72L3_HUMAN", "id": "A0A1W2PQJ5-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72 like protein 3", "aln": "ML---SSPLRVAVVCVSNVNRSMEAHSILRRKGLSVRSFGTESHVRLPGPRPNRPVVYDFATTYKQMYNDLLRKDRERYTRNGILHILGRNERIKPGPERFQECTDSFDVIFTCEESVYDTVVEDLCSREQQTFQPVHVINMDIQDTLEDATLGAFLICEICQCLQ------QSDDI--EDNLEELLLQMEE-KAGKSFLHTVCFY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1W2PR75-1", "uniprot_id": "S72L6_HUMAN", "id": "A0A1W2PR75-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72 like protein 6", "aln": "ML---SSPLRVAVVCVSNINRSMEAHSILRRKGLSVRSFGTESHVRLPGRRPNHPVVYDFATTYKEMYNDLLRKDRECYTHNGILHILGRNERIKPGPERFQECTEFFDVIFTCEERVYDTVVEDLCSREQQTFQPVHVINMDIKDTLEGAILGAFLICEICQCLQ------QSDDM--EDSLEELLLQMEE-KAGKSFLHTVCFY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWE4-1", "uniprot_id": "Q9VWE4_DROME", "id": "Q9VWE4-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "aln": "MTD--PSKLAVAVVCSSNMNRSMEAHNFLAKKGFNVRSYGTGERVKLPGMAFDKPNVYEFGTKYEDIYRDLESKDKEFYTQNGLLHMLDRNRRIKKCPERFQDTKEQFDIIVTVEERVYDLVVMHMESMESVDNRPVHVLNVDVVDNAEDALMGAFVITDMINMMA------KSTDL--DNDIDELIQEFEE-RRKRVILHSVLFY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53538-1", "uniprot_id": "SSU72_YEAST", "id": "P53538-1", "name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "aln": "MPSHRNSNLKFCTVCASNNNRSMESHKVLQEAGYNVSSYGTGSAVRLPGLSIDKPNVYSFGTPYNDIYNDLLSQSADRYKSNGLLQMLDRNRRLKKAPEKWQESTKVFDFVFTCEERCFDAVCEDLMNRGGKLNKIVHVINVDIKDDDENAKIGSKAILELADMLNDKIEQCEKDDIPFEDCIMDILTEWQSSHSQLPSLYAPSYY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * ...** ** *****:*..* . * .* *:** *:*** ::* :*.* * *.::*.** :. : *. **:*::*.**.*:* **::*. . **.:.* ** :* * .: . : ***:*::: * * * :*: * :: : : .. *: :: : ::: : :. : *:: :*", "identical_positions": 61, "similar_positions": 66, "identity": "29.61%" }, { "cls_id": "homologset.agr.SGD:S000005167", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C9S8-1", "uniprot_id": "ATG4A_MOUSE", "id": "Q8C9S8-1", "name": "Cysteine protease ATG4A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MESVMSKYENQ---------ILIFPDYLEEFPDTDELVWILGKQHP--------------------------------------------------------------------------LKTEKSKLLSDISARLWFTYRRKFSPIGGT-----------------------------GPSSDAGWGCMLRCGQMMLAQALICRHLGRDWNWERQK--------------------------------------------------------------------EQPKEYQRILQCFLDRK--DCCYSIHQMAQMGVGEG-KSIGEWFGPNTVAQVIKKLALFD-----EWNSLAVYVSMDNTVVIEDIKKMCCVLPVGAADPAG----DFLTASNQSR---DTSVPCSAWKPLLLIVPLRLGINQINPVYVEAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDIEESGLVDDQTF---HCLQSPQRMSILNLDPSVALGFFCKEEKDFDNWCSLVQK-EILKEN-----------------------------LRMFELVQKHPSHWPPFVPP------AKPEVTTTGAEF------IESTEQLEDFELE-EDFEILSVG----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JFS9-1", "uniprot_id": "A0A0G2JFS9_MOUSE", "id": "A0A0G2JFS9-1", "name": "Cysteine protease", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MESVMSKYENQ---------ILIFPDYLEEFPDTDELVWILGKQHP--------------------------------------------------------------------------FKTEKSKLLSDISARLWFTYRRKFSPIGGT-----------------------------GPSSDAGWGCMLRCGQMMLAQALICRHLGRDWNWERQK--------------------------------------------------------------------EQPKEYQRILQCFLDRK--DCCYSIHQMAQMGVGEG-KSIGEWFGPNTVAQVIKKLTLFD-----EWNSLAVYVSMDNTVVIEDIKKMCCVLPVGAADPAG----DFLTVSNQSR---DTSVPCSAWKPLLLIVPLRLGINQINPVYVEAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDIEESGLVDDQTF---HCLQSPQRMSILNLDPSVALGFFCKEEKDFDNWCSLVQK-EILKEN-----------------------------LRMFELVQKHPSHWPPFVPP------AKPEVTTTGAEF------IESTEQLEDFELE-EDFEILSVG----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A6C4-1", "uniprot_id": "A0A8I6A6C4_RAT", "id": "A0A8I6A6C4-1", "name": "Cysteine protease", "aln": "--------------------------------------------------------------------------------------------------------------------------------MTAGEWSQGV-------ERSTVMSKYENQ---------IIIFTEYLEEFPDTDELVWILGKPHL--------------------------------------------------------------------------LKTEKSKLLSDISARLWFTYRRKFSPIGGT-----------------------------GPSSDAGWGCMLRCGQMMLAQALICRHLGRDWNWERQK--------------------------------------------------------------------EQPKEYQRILQCFLDRK--DCCYSIHQMAQMGVGEG-KSIGEWFGPNTVAQVIKKLALFD-----EWNSLAVYVSMDNTVVIEDIKKMCCVLPVGAADTAGESPPDSLIASSQSK---GTSAPCLAWKPLLLIVPLRLGINQINPVYIEAFKECFKMPQSLGALGGKPNNAYYFIGSLGDELIFLDPHTTQTFVDTEESGLVDDHTF---HCLQSPQRMSILNLDPSVALGFFCKEEKDFDNWCSLVQK-EILKEN-----------------------------LRMFELVQKHPSHWPPFVPP------AKPEVTTTGAEF------IDSTEQLEDFDLE-EDFEILSV-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WYN0-1", "uniprot_id": "ATG4A_HUMAN", "id": "Q8WYN0-1", "name": "Cysteine protease ATG4A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MESVLSKYEDQ---------ITIFTDYLEEYPDTDELVWILGKQHL--------------------------------------------------------------------------LKTEKSKLLSDISARLWFTYRRKFSPIGGT-----------------------------GPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEKQK--------------------------------------------------------------------EQPKEYQRILQCFLDRK--DCCYSIHQMAQMGVGEG-KSIGEWFGPNTVAQVLKKLALFD-----EWNSLAVYVSMDNTVVIEDIKKMCRVLPL-SADTAGDRPPDSLTASNQSK---GTSAYCSAWKPLLLIVPLRLGINQINPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDTEENGTVNDQTF---HCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQK-EILKEN-----------------------------LRMFELVQKHPSHWPPFVPP------AKPEVTTTGAEF------IDSTEQLEEFDLE-EDFEILSV-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BGE6-1", "uniprot_id": "ATG4B_MOUSE", "id": "Q8BGE6-1", "name": "Cysteine protease ATG4B", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MDAATLTYD------------TLRFAEFEDFPETSEPVWILGRKYS--------------------------------------------------------------------------IFTEKDEILSDVASRLWFTYRRNFPAIGGT-----------------------------GPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRK--------------------------------------------------------------------RQPDSYFNVLNAFLDRK--DSYYSIHQIAQMGVGEG-KSIGQWYGPNTVAQVLKKLAVFD-----TWSSLAVHIAMDNTVVMEEIRRLCRANLPCAGAAALPTDSERHCNGFPAG--AEVTNRPSAWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVELTDSCFIPDESF---HCQHPPSRMGIGELDPSIAVGFFCKTEEDFNDWCQQVKKLSQLGGA-----------------------------LPMFELVEQQPSHL------------ACQDVLNLSLDS------SDVERLERFFDSEDEDFEILSL-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2QC33-1", "uniprot_id": "ATG4B_RAT", "id": "A0A0G2QC33-1", "name": "Cysteine protease ATG4B", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MDAATLTYD------------TLRFAEFEDFPETSEPVWILGRKYS--------------------------------------------------------------------------IFTEKDEILSDVASRLWFTYRRNFPAIGGT-----------------------------GPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRK--------------------------------------------------------------------RQPDSYFSVLNAFLDRK--DSYYSIHQIAQMGVGEG-KSIGQWYGPNTVAQVLKKLAVFD-----TWSSLAVHIAMDNTVVMEEIRRLCRASLPCAGAAALSMESERHCNGLPAG--AEVTNRPLAWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVELTDSCFIPDESF---HCQHPPCRMGIGELDPSIAVGFFCKTEEDFNDWCQQVKKLSQLGGA-----------------------------LPMFELVEQQPSHL------------ACQDVLNLSLDS------SDVERLERFFDSEDEDFEILSL-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y4P1-1", "uniprot_id": "ATG4B_HUMAN", "id": "Q9Y4P1-1", "name": "Cysteine protease ATG4B", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MDAATLTYD------------TLRFAEFEDFPETSEPVWILGRKYS--------------------------------------------------------------------------IFTEKDEILSDVASRLWFTYRKNFPAIGGT-----------------------------GPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRK--------------------------------------------------------------------RQPDSYFSVLNAFIDRK--DSYYSIHQIAQMGVGEG-KSIGQWYGPNTVAQVLKKLAVFD-----TWSSLAVHIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAG--AEVTNRPSPWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESF---HCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGA-----------------------------LPMFELVELQPSHL------------ACPDVLNLSLDS------SDVERLERFFDSEDEDFEILSL-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DG88-1", "uniprot_id": "ATG4B_DANRE", "id": "Q6DG88-1", "name": "Cysteine protease ATG4B", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MDAATLTYD------------SLRFGEIEDFPETSDPVWILGKQFS--------------------------------------------------------------------------ALTEKDDILADVTSRLWFTYRKNFQPIGGT-----------------------------GPTSDTGWGCMLRCGQMILGEALICRHLGRDWKWSPGQ--------------------------------------------------------------------RQRPEYVSILNAFIDKK--DSYYSIHQIAQMGVGEG-KSIGQWYGPNTVAQVLKKLAVFD-----SWSRLAVHVAMDNTVVIEEIKRLCMPWLDFDRGACAVSEEPREMNGDLEGACALAEEETALWKPLVLLIPLRLGLSDINEAYIEPLKQCFMMPQSLGVIGGKPNSAHYFIGFVGDELIYLDPHTTQPAVDPSEDGHFPDDSY---HCQHPPCRMHICELDPSIAAGFFCQTEDDFDDWCAQIRKVSNCRG------------------------------LPMFELVDSQPSHL------------ITADVLNLTPDF------SDSDRLERFFDSEDEEFEILSL-----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPW2-1", "uniprot_id": "Q9VPW2_DROME", "id": "Q9VPW2-1", "name": "Cysteine protease", "aln": "-------------------------------------------------------------------------------------------------------------------------------MLVGLSDQLAR-------IMESVFEAYLGPDSVLASAVGQAVGSGEPEDIPRRNTDVWVLGKKYN--------------------------------------------------------------------------AIQELELIRRDIQSRLWCTYRHGFSPLGEV-----------------------------QLTTDKGWGCMLRCGQMVLAQALIDLHLGRDWFWTPDC--------------------------------------------------------------------RDAT-YLKIVNRFEDVR--NSFYSIHQIAQMGESQN-KAVGEWLGPNTVAQILKKLVRFD-----DWSSLAIHVAMDSTVVLDDVYASCR-----------------------EG---------GSWKPLLLIIPLRLGITDINPLYVPALKRCLELDSSCGMIGGRPNQALYFLGYVDDEVLYLDPHTTQRTGAVAQKTAAAEQDYDETYHQKHAARLNFSAMDPSLAVCFLCKTSDSFESLLTKLKEEVLSLCS-----------------------------PALFEISQTRAVDWDTTEDI------DWPTMPDIDWPAGT----SDSDSFAIVEESGRDSDAGCSGAIGSGKKPSERAVI---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q811C2-1", "uniprot_id": "ATG4C_MOUSE", "id": "Q811C2-1", "name": "Cysteine protease ATG4C", "aln": "------------------------------------MEASG-------------------------------------------------------------------------------------------TDEVDK-------LKTKFISAWNN--------MKYSWVLKT-KTYFSRNSPVLLLGKCYH------FKYEDESKMLPARSGCAIE----------------------------------------------DHVIAGNVEEFRKDFISRIWLTYREEFPQIEAS-----------------------------ALTTDCGWGCTLRTGQMLLAQGLILHFLGRAWTWPDALHIENADSDSWTSNTVKKFTASFEASLSG----------------DRELRTPAVSLKETSGKCPDDHAVRNEAYHRKIISWFGDSP--VAVFGLHRLIEFGKKSG-KKAGDWYGPAVVAHILRKAVEEAR--HPDLQGLTIYVAQDCTVYNSDVIDKQ---------------------------TDSVTAGDARDKAVIILVPVRLGGERTNTDYLEFVKGVLSLEYCVGIIGGKPKQSYYFAGFQDDSLIYMDPHYCQSFVDVSIKDFPLETFH-----CPSPKKMSFRKMDPSCTIGFYCRNVQDFERASEEITKML--------------------------KISS-KEKYPLFTFVNGHSKDFDFT------------STAASEEDL------FSEDERKNFKRFSTEEFVLL-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M3M0-1", "uniprot_id": "F1M3M0_RAT", "id": "F1M3M0-1", "name": "Cysteine protease", "aln": "------------------------------------MEASG-------------------------------------------------------------------------------------------TDEVDK-------LKTKFISAWNN--------MKYSWVLKT-KTYFSRNSPVLLLGKCYH------FKYEDESKVLPARSGCAIE----------------------------------------------DHVIAGNVEEFRKDFISRIWLTYREEFPQIEAS-----------------------------ALTTDCGWGCTLRTGQMLLAQGLILHFLGRAWTWPDALHIESSDSDSWTSNTIHKFTASFEASLSG----------------ERELRTPAVSLKETSGKHPDDHAVQSEIYHRQIISWFGDSP--VAVFGLHRLIEFGKKSG-KKAGDWYGPAVVAHILRKAVEEAR--HPDLQGLTIYVAQDCTVYNSDVIDKQ---------------------------TDSVTAGDARDKAVIILVPVRLGGERTNIDYLEFVKGVLSLEYCVGIIGGKPKQSYYFAGFQDDSLIYMDPHYCQSFVDVSIKDFPLETFH-----CPSPKKMSFRKMDPSCTIGFYCRNVQDFERASEEITKML--------------------------KISS-KEKYPLFTFVNGHSRDFDFT------------STAASEEDL------FLEDEKKNFKRFSTEEFVLL-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96DT6-1", "uniprot_id": "ATG4C_HUMAN", "id": "Q96DT6-1", "name": "Cysteine protease ATG4C", "aln": "------------------------------------MEATG-------------------------------------------------------------------------------------------TDEVDK-------LKTKFISAWNN--------MKYSWVLKT-KTYFSRNSPVLLLGKCYH------FKYEDEDKTLPAESGCTIE----------------------------------------------DHVIAGNVEEFRKDFISRIWLTYREEFPQIEGS-----------------------------ALTTDCGWGCTLRTGQMLLAQGLILHFLGRAWTWPDALNIENSDSESWTSHTVKKFTASFEASLSG----------------EREFKTPTISLKETIGKYSDDHEMRNEVYHRKIISWFGDSP--LALFGLHQLIEYGKKSG-KKAGDWYGPAVVAHILRKAVEEAR--HPDLQGITIYVAQDCTVYNSDVIDKQ---------------------------SASMTSDNADDKAVIILVPVRLGGERTNTDYLEFVKGILSLEYCVGIIGGKPKQSYYFAGFQDDSLIYMDPHYCQSFVDVSIKDFPLETFH-----CPSPKKMSFRKMDPSCTIGFYCRNVQDFKRASEEITKML--------------------------KFSS-KEKYPLFTFVNGHSRDYDFT------------STTTNEEDL------FSEDEKKQLKRFSTEEFVLL-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BGV9-1", "uniprot_id": "ATG4D_MOUSE", "id": "Q8BGV9-1", "name": "Cysteine protease ATG4D", "aln": "------------------------------------MNSVSPAAAQYRSGS-SEDARR-ADCRRPRGQTRIPDPSNLGPSGS------------------------------------GVAALGSSGTDPAEPDEVDK-------FKAKFLTAWNN--------VKYGWAVKS-RTSFSKISTVHLCGRCYH------FEGEGD------------------------------------------------------------------IQRFQRDFVSRLWLTYRRDFPPLAGG-----------------------------SLTSDCGWGCMLRSGQMMLAQGLLLHFLPRDWRWVEGTGLASS--EMPGPASPSRCRGP-------------------------GRRGPPRWTQGAL-------EMEQDRWHRRIVSWFADHP--RAPFGLHRLVELGRSSG-KKAGDWYGPSVVAHILRKAVESC----SEVSRLVVYVSQDCTVYKADVAR-----------------------------LLSWPDPTAEWKSVVILVPVRLGGETLNPVYVPCVKELLRSELCLGIMGGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDVSQPSFPLESFH-----CTSPRKMAFAKMDPSCTVGFYAGNRKEFETLCSELMRIL--------------------------SSSSVTERYPMFTVAEGHAQDHSLDALCT--------QLSQPTLRL------PCTGRLLKAKRPSSEDFVFL-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R5T6-1", "uniprot_id": "M0R5T6_RAT", "id": "M0R5T6-1", "name": "Cysteine protease", "aln": "------------------------------------MNSVSPAAAQYRSGS-PEDARR-PDCRRPRGQTRIPDPSNLGPSGS------------------------------------GVAALGSTGTDPAEPDEVDK-------FKTKFLTAWNN--------VKYGWAVKS-RTSFSKISSVHLCGRCYH------FEGEGD------------------------------------------------------------------IQRFQRDFVSRLWLTYRRDFPPLAG------------------------------SLTSDCGWGCMLRSGQMMLAQGLLLHFLPRDWRWVEGTGLASS--EMPGPASPSRYRGP-------------------------GRRGPLRCAQGAL-------EMEPDRWHRRIVSWFADHP--QAPFGLHRLVELGQSSG-KKAGDWYGPSVVAHILRKAVESC----SEVTRLVVYVSQDCTVYKADVAR-----------------------------LVSWPDPTAEWKSVVILVPVRLGGETLNPVYVPCVKELLRSELCLGIMGGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDVNQANFPLESFH-----CTSPRKMAFAKMDPSCTVGFYAGNRKEFETLCSELMRIL--------------------------SSSSVTERYPMFTVAEGHAQDHSLDALCT--------QLSQPTLRL------PCTGRLLKAKRPSSEDFVFL-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86TL0-1", "uniprot_id": "ATG4D_HUMAN", "id": "Q86TL0-1", "name": "Cysteine protease ATG4D", "aln": "------------------------------------MNSVSPAAAQYRSSS-PEDARRRPEARRPRG-PRGPDPNGLGPSGA------------------------------------SGPALGSPGAGPSEPDEVDK-------FKAKFLTAWNN--------VKYGWVVKS-RTSFSKISSIHLCGRRYR------FEGEGD------------------------------------------------------------------IQRFQRDFVSRLWLTYRRDFPPLPGG-----------------------------CLTSDCGWGCMLRSGQMMLAQGLLLHFLPRDWTWAEGMGLGPP--ELSGSASPSRYHGP-------------------------ARWMPPRWAQGAP-------ELEQERRHRQIVSWFADHP--RAPFGLHRLVELGQSSG-KKAGDWYGPSLVAHILRKAVESC----SDVTRLVVYVSQDCTVYKADVAR-----------------------------LVARPDPTAEWKSVVILVPVRLGGETLNPVYVPCVKELLRCELCLGIMGGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDVSQADFPLESFH-----CTSPRKMAFAKMDPSCTVGFYAGDRKEFETLCSELTRVL--------------------------SSSSATERYPMFTLAEGHAQDHSLDDLCS--------QLAQPTLRL------PRTGRLLRAKRPSSEDFVFL-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "R4GER2-1", "uniprot_id": "ATG4D_DANRE", "id": "R4GER2-1", "name": "Cysteine protease atg4da", "aln": "------------------------------------MNSVSPSAVQYIVGGGAHEDKASASSKRHLGHGAVPDGIREG-SG--------------------------------------------------EPDEVDR-------LKAKFMSAWNN--------VKYGWTVKS-KTSFNKSSPLILLGQSFL------FNNEDE------------------------------------------------------------------VERFRQTFVSCVWLTYRREFPQLDGS-----------------------------SLTTDCGWGCMLRSGQMMLAQGLLLHLMPTDWRWSDCHALTDVDFEVLKPRSPSRPAGMSMPSFSSSWSSSIPQINPSPGITEAHRRAPARCPSASP-------DPQVDALHRKVVSCFGDHP--SAPFGVHQLVELGKESG-KRAGDWYGPSVVAHMLRKAVARA----AEFEDLAVYVAQDCTVYKEDVMS-----------------------------LCE--SSGVGWKSVVILVPVRLGGESLNPSYIECVKNILKLKCCIGIIGGKPKHSLFFVGFQDEQLLYLDPHYCQPVVDVTQANFSLESFH-----CNSPRKMNFSRMDPSCTIGLYARSKTDFESLCTAVSEAL--------------------------SSS--KEKYPIFTFVEGRGQIYGMEGPSG-------GSVDAPAHIF------TCSRLSRNNKRGSTDEFVLL-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VF80-1", "uniprot_id": "Q9VF80_DROME", "id": "Q9VF80-1", "name": "Cysteine protease", "aln": "MNYDGLLSKLTDEKLMLFEAAGEGTIVEGSRICGQDADPLSLPLVEDGAIEEEQAAPIQTIHRTVFAVPRVPSPSPVSTSGANLNLKTENAATATPQRKISTSSRFMNAFSQLYGGGNSGPSCGHVEQHNEEPGDLSANRTPTKGMESKLVAMWHN--------VKYGWSGKMRQTSFSKEQPVWLLGRCYHRRFTPPVSMESSITELPSGADTTPDNATSAFDSIQATSTSTSLYPALNPQQIDEIVVPQELGMDAVENQVGEQPWEEGIEGFRRDFYSRIWMTYRREFPIMNGS-----------------------------NYTSDCGWGCMLRSGQMLFAQGLICHFLGRSWRYDSESQLHST---------------------------------------------------------------YEDNMHKKIVKWFGDSSSKSSPFSIHALVRLGEHLG-KKPGDWYGPASVSYLLKHALEHAAQENADFDNISVYVAKDCTIYLQDIEDQCSIPEPAPKPHVP------WQQAKRPQAETTKTEQQQHWKSLIVLIPLRLGSDKLNPVYAHCLKLLLSTEHCLGILGGKPKHSLYFVGFQEDRLIHLDPHYCQEMVDVNQENFSLHSFH-----CKSPRKLKASKMDPSCCIGFYCATKSDFDNFMESVQLYLHPMRCASGATVDKAAGSHHTTPQSSHQTEQTEMNYPLFSFSRGRCMDHERDEMSDSLYKPLIKQVASLAQELGAQLAPPQHGDEHDQDDSESEEFVLL-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53867-1", "uniprot_id": "ATG4_YEAST", "id": "P53867-1", "name": "Cysteine protease ATG4", "aln": "------------------------------------MQRWLQLWKMDLVQKVSHG------------------------------------------------------------------------VFEGSSEEPAALMNHDYIVLGEVYPERDEE----SGAEQCEQDCRYRGEAVSDGFLSSLFGREIS----------------------------------------------------------------------------SYTKEFLLDVQSRVNFTYRTRFVPIARAPDGPSPLSLNLLVRTNPISTIEDYIANPDCFNTDIGWGCMIRTGQSLLGNALQILHLGRDFRVNGNE---------------------------------------------------------------------SLERESKFVNWFNDTP--EAPFSLHNFVSAGTELSDKRPGEWFGPAATARSIQSLIYGFP--ECGIDDCIVSVSSG-DIYENEVEKVFAE---------------------------------NPNSRILFLLGVKLGINAVNESYRESICGILSSTQSVGIAGGRPSSSLYFFGYQGNEFLHFDPHIPQPAVEDSFVESCHTSKFG---------KLQLSEMDPSMLIGILIKGEKDWQQWKLEVAESAIINVLAKR-------------------MDDFDVSCSMDDVESVSSNSMKKDASNNENLGVLEGDYVDIGAIFPHTTNTEDVDEYDCFQDIHCKKQKIVVMGNTHTVNANLTDYEVEGVLVEKETVGIHSPIDEKC", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: . : . : : *** * : .:* **** :* ** ::.:.* : : .:. * * . :.:* : * . * *:* ** .: :: : :: . : :: ::.:: ::** * * . : . * **:* : :* * : .:.:*** * . :: :*** : .:. : : . .. ", "identical_positions": 40, "similar_positions": 70, "identity": "4.9%" }, { "cls_id": "homologset.agr.SGD:S000005168", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TQC7-1", "uniprot_id": "GPTC2_MOUSE", "id": "Q7TQC7-1", "name": "G patch domain-containing protein 2", "aln": "-------MFGADGRPAIGTAAG----------------------KSWHFS----------------------RTMEELVHDLVSALEESSEQARGGFAETGEHSRNLSCPLKRQARKRR----GRKRRSYN----------VHHPWETGHCLSEGSDSSLEEPSKDYREKHSNNKKDRSDSDD--QMLVAKRRPSSNLSSSVRGKRLLWHESDFAVDS----LGNRTLRRRRKVKRMAVDLPQDVSSKRTMTQLPEGCRDQ----DMDNDRASQYPEFT------------------------RKKVKKRKLKGIRPGPKTQEEGGVLESEERSQPNKDRMEYEEQKASDELRSESDT-----------------------------------------------------------------------------------------------------SSLSSTDAGLFTNDEGRQGDDEQSDWFYEKE--------SGGACGIAGVVPWWEKDEPAELDTNLPDPVFESILSGSFPLMSHPGRGGFQARLSRLHGTPSKNIKKSSG---APPSMLSAPGPGSNKRMVHFSPDAHRHDHWFSPGARTEHGQHQLLRDNRAERGHKKSCSLKTASRQTSMHLG-----SLCTGDIKRRRKAAP-----------------------------------LPG--PTAAG-IVGENAQPILESNIGNRMLQSMGWTPGSGLGRDG-RGIAEPVQAVQRPKGLGLGFPLPKSSPTSPAPTSGNPA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GC35-1", "uniprot_id": "A0A8I6GC35_RAT", "id": "A0A8I6GC35-1", "name": "", "aln": "-------MFGADGRPAIGAAAAAR--------------------KSWHFS----------------------RTMEELVHDLVSALEESSEQARGGFAETGDHSRNLSCPLKRQARKRR----GRKRRSYN----------VHHPWETGHCLSEGSDSSLEEPSKDYREKHSNNKKDRSDSDD--QMLVAKRRPSSTLNNSVRGKRLLWHESDFAVDN----LGNRTLRRRRKVKRMAVDLPQDISTKRTMTQPPDGCRDQ----DMDSDGASQYPEFI------------------------RSKVKKRRLKVIR--PKAPEEGAVLESEEVSQADKDKMEYVEPKASDELRSESDS-----------------------------------------------------------------------------------------------------SSLSSTDAGLFTNDEGRQGDDEQSDWFYEKE--------SGGACGIAGVAPWWEEEGPVELDTNLPDPVFESILSGSFPLMSHPGRRGFQARLSCLHGVPSKNIKKSAG---APPSMMSAPGPISNKRMVHFSPDAHHHDHWFSPGARTEHGQHQLLRDNRAERGHKKSCSVKTASRQTSMHLG-----SLCTGDIKRRRKAAP-----------------------------------LPGPGPTTTG-IVGENAQPILESNIGNRMLQSMGWTPGAGLGRDG-RGISEPVQAIQRPKGLGLGFPLPKSTPTSPVPASGKPA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NW75-1", "uniprot_id": "GPTC2_HUMAN", "id": "Q9NW75-1", "name": "G patch domain-containing protein 2", "aln": "-------MFGAAGRQPIGAPAAG---------------------NSWHFS----------------------RTMEELVHDLVSALEESSEQARGGFAETGDHSRSISCPLKRQARKRR----GRKRRSYN----------VHHPWETGHCLSEGSDSSLEEPSKDYRENHNNNKKDHSDSDD--QMLVAKRRPSSNLNNNVRGKRPLWHESDFAVDN----VGNRTLRRRRKVKRMAVDLPQDISNKRTMTQPPEGCRDQ----DMDSDRAYQYQEFT------------------------KNKVKKRKLKIIRQGPKIQDEGVVLESEETNQTNKDKMECEEQKVSDELMSESDS-----------------------------------------------------------------------------------------------------SSLSSTDAGLFTNDEGRQGDDEQSDWFYEKE--------SGGACGITGVVPWWEKEDPTELDKNVPDPVFESILTGSFPLMSHPSRRGFQARLSRLHGMSSKNIKKSGG---TPTSMVPIPGPVGNKRMVHFSPDSHHHDHWFSPGARTEHDQHQLLRDNRAERGHKKNCSVRTASRQTSMHLG-----SLCTGDIKRRRKAAP-----------------------------------LPG--PTTAG-FVGENAQPILENNIGNRMLQNMGWTPGSGLGRDG-KGISEPIQAMQRPKGLGLGFPLPKSTSATTTPNAGKSA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53866-1", "uniprot_id": "SQS1_YEAST", "id": "P53866-1", "name": "Protein SQS1", "aln": "MAKRHSHYQGSRRRHARGSNSKKAGRGNAKGIQGRKIKKKPTPTNSWHNSSIPLGEGDLDDVGADFNPGRAFISPKTIEDYYFGRDAKSRSMKMGGLRPGNRYDSSTDLQAGRAAFRKRPMQFVKAKEVYDPSHNMIQKLRAKNETKNSEEIVEREADVFEEPGKMTSDVEYINNEDSENEDDDSQNSPSTDHSLSSNESKVEDGDLFFVDEEAQQSPDLTKIKRVCIEEIARPREVAIEFDPILTIGKVELSVSEGNESKEISVDVPNKGNKTYHPFAGYISNVLHGMHTSDSDNDELDYEIETENNSEPLYESSASSEVDQGFNYVGQRHNSRADNNLLPSPSPQLTEDIKCLSINGTKTFEGNNDNLPSPASEELEFGFKEEDFVINTNDIVVSNIRMGGVDNSYYLRCYRLLGDYDFHWIDQDLLTDFVVDELGLPEDRLPAYLNFIKNSLIPKIEPAEPTYSDIPISDSSDEGDSYEGDSYEDDEDMASSVVHSDIEEGLDDLIAYTLKHDTERFKTFETKSLETKGKGKKKKLLIDDALALDTETLETLQSKFSKRIETKAKKRKAKEDFIDQENRNSNDMLKKYPYGLHIQNIKDEFESFLSRNNDRLTFPPLDPHGNKTVMKIAKHYNMKSSKIGKANHTSVVVEKIKKTKWSSPNYSLIDQLMRQRPVFMRIDIRRPREEQAAFERTKTIRGKFHVKEGEIVGQNAPEIGNENIGRRMLEKLGWKSGEGLGIQGNKGISEPIFAKIKKNRSGLRHSES---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: * . *: : :*** * : : : . .. :* . **: . :. . . * * ::* : :. *: .:: :... : * . . :***.* : . *::* .:.** * :. :. *. ...*.. :: :.: . : . :.. : :.:*::: :: :. . .:* ..: *: .. * * ..: :.. * .: : : ... .:.::: : . : :::: . * . .. ..* :.: .*.. :**. :.* : :.* *. *: .: .: :. . .:.. ...: . . *: . . *. *:. **.*:... : .:: . .*. : ::. . * :: . : .:.:.:* :*:*. .: . . .* ::* *: . .**: : ::* : * . * :**:** * :.***.***:.:**..* *** :* :**:**: * : : ** .. . ", "identical_positions": 85, "similar_positions": 220, "identity": "10.87%" }, { "cls_id": "homologset.agr.SGD:S000005171", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9Q8D0-1", "uniprot_id": "DJC21_MOUSE", "id": "E9Q8D0-1", "name": "DnaJ homolog subfamily C member 21", "aln": "--------------------------------------------------------------------------------MKCHYEALGVRRDASEEELKKAYRKLALRWHPDKNLDNAAEAAEQFKLIQAAYDVLSDPQERAWYDNHREALLKGGLDGEYQD------------DSLDLLHYFTVTCYSGYGDDERGFYAVYRVVFELIAKEELECMS-------------------------------EGDVEDFPTFGDSQSDYDTVVHPFYAHWQSFCTQKNFSWKEEYDTRQASNRWEKRAMEKENKKIRDRARKEKNELVRQLVAFIRKRDKRVQAHRKLVEEQNAEKARKAEEMRRQQKLKQAKLAEQYREQSWMTMANLEKELQEMEARYEKEFGDGSD-ENEVEDQEPR-----NGLDGKDSE-EAEEAELYQDLYCPACDKSFKTEKAMKNHEKSKKHREMVALLKQQLEEEEEQFSG-------------------------------VQMDENVLNANSEEEMEDTPKQKLSKKQKKKK--QKSAQNFDDNFNENGTEEGGKIAPEKTKSNEDNAKELENRPQENTCITETTEACEDPKSEAKSVPKSKGKK----TKDVKKSVKAP-----AEAQPVSDVLISCATCHSEFPSRNKLFDHLKATGHARAPSATASLNSVT--RNKKEKRRSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2QC19-1", "uniprot_id": "A0A0G2QC19_RAT", "id": "A0A0G2QC19-1", "name": "DnaJ homolog subfamily C member 21", "aln": "MRSRRRRPLRASACRSPRCPPPRASSVPRRCRRRRRARWLAGCWRRAPTGGEDSQRRRCRFCPGPGVGPAPGPGPVSSPAMKCHYEALGVRRDASEEELKKAYRKLALRWHPDKNLDNAAEAAEQFKLIQAAYDVLSDPQERAWYDNHREALLKGGLDGEYQD------------DSLDLLHYFTVTCYSGYGDDEKGFYAVYRDVFALIAKEELECMS-------------------------------EGGAEDFPTFGDSQSDYDTVVHPFYAYWQSFCTQKNFAWKEEYDTRQASNRWEKRAMEKENKKIRDKARKEKNELVRQLVAFIRKRDKRVQAHRKLVEEQNAEKARKAEEMRRQQKLKQAKLAEQYREQSWMTMANLEKELREMEARYEKEFGDGSD-ENEVEEQEAK-----DAVDGKDSE-EAEETELYGDLYCPACDKSFKTEKAMKNHEKSKKHREMVALLKQQLEEEEEQFSG-------------------------------AQMDENLLNANSEEETEDIPRQKRSKKQKKRK--QKSVQNFDDNFNENGTEEGGKIDPKETKSNEDNAKELENRPQENICITETTEACEDPKSEAKSVPKSKGKK----TKDVKKSVKVP-----AEPQPVSDVLISCATCHSEFPSRNKLFDHLKATGHARAPSAAASLDSVSSSRNKKEKRRNR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5F1R6-1", "uniprot_id": "DJC21_HUMAN", "id": "Q5F1R6-1", "name": "DnaJ homolog subfamily C member 21", "aln": "--------------------------------------------------------------------------------MKCHYEALGVRRDASEEELKKAYRKLALKWHPDKNLDNAAEAAEQFKLIQAAYDVLSDPQERAWYDNHREALLKGGFDGEYQD------------DSLDLLRYFTVTCYSGYGDDEKGFYTVYRNVFEMIAKEELESVL-------------------------------EEEVDDFPTFGDSQSDYDTVVHPFYAYWQSFCTQKNFAWKEEYDTRQASNRWEKRAMEKENKKIRDKARKEKNELVRQLVAFIRKRDKRVQAHRKLVEEQNAEKARKAEEMRRQQKLKQAKLVEQYREQSWMTMANLEKELQEMEARYEKEFGDGSD-ENEMEEHELK-----DEEDGKDSD-EAEDAELYDDLYCPACDKSFKTEKAMKNHEKSKKHREMVALLKQQLEEEEENFSR-------------------------------PQIDENPLDDNSEEEMEDAPKQKLSKKQKKKK--QKPAQNYDDNFNVNGPGEGVKVDPEDTNLNQDSAKELEDSPQENVSVTEIIKPCDDPKSEAKSVPKPKGKK----TKDMKKPVRVP-----AEPQTMS-VLISCTTCHSEFPSRNKLFDHLKATGHARAPSS-SSLNSATSSQSKKEKRKNR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PGY5-1", "uniprot_id": "DJC21_DANRE", "id": "Q6PGY5-1", "name": "DnaJ homolog subfamily C member 21", "aln": "--------------------------------------------------------------------------------MKCHYEVLGVKRDASDDDLKKAYRKLALKWHPDKNLDNAEDAAEQFKLIQAAYDVLSDPQERAWYDNHREALLKGGVSGEYQD------------DSIDLVQFFTVTCYSGYGDDEKGFYAVYRNVFESIVKEEKEHSKDE-----------------------------EDEEDEFPSFGESESDYDTVVHLFYGYWQSFCTRKNFAWKEEYDTRQASNRWEKRAMEKENKKTRDKARKEHNELVRQLVAFVRKRDKRVQAHKKLVEEQNAEKAKKVEELRRKQKLSQAKLAEDYQEQSWTAMSELEKELQQMEAEYGQEFGDASDSEENEEELESRDIANVDGVDAVMADGAAEMDDYYDDLYCPACDKSFKSDKAMKNHSKSKKHREMVALLRQQLEEEDESLSQN---------------------------CAEREEDDEEEDDDDDDEQNDTSKQKLSKRQKKKKRLQKPVNNLPEAPETVSP---VPQSTEEHLSPAPDSGNTEDTPVPSEDPDDGVKPDGQENTNQKSTAKTKGKKG---GKDSKKSSKAHG---GVEAAPEKEVNLRCVTCQYEFTTRNKLFDHLKSTGHATALSS---SNTSQTSKKKKDSRKNR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0X8-1", "uniprot_id": "Q9W0X8_DROME", "id": "Q9W0X8-1", "name": "DnaJ homolog subfamily C member 21", "aln": "--------------------------------------------------------------------------------MRCYYEELELQRNANDGDIKSAYRKMALRWHPDKNPDRLAEAKERFQLIQQAYEVLSDPQERSWYDNHREQILRG-KNSDYAE------------NCLDVFQFFTSSCYKGYGDNEHGFYRVYTDVFVQIASEDLEFMD-K-----------------------------DDRLGMAPDFGHSNSSYEDVVGPFYAFWQAYSTRKTYDWLCPYDVREIKERFILRKVEKEMKKIVQAARKERNEEVRNLVNFVRKRDPRVQAYRRMLEERVEANRLKQEEKRKEQLRKRQEELAAVRKNNVFNEG-YEEQLKQLEQQYDSKSEDYTDEDENDDDGEDF-----DHEGGQEAE--EYEVEYVDDLYCVACNKTFKNAKARANHEESKKHNENVDRLCQEMEEEEDAFHN-------------------------------EPHEDSLMGVQESLEELQVSEDQISFDGVPSEEESSLAKRTKKNKKARKSAVKQAQAEGSDEPDEPIEKKAIKSESEDEDWSKGKKASKKSKSKKTTTRKVKLLEQTVSEPNTKEATVAPKS--GDEDLDPTKSQHTCVTCRLVFDSKNKLFAHLKKTNHGVYIPK-AKPNVEGKPPGKAKGKRNK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53863-1", "uniprot_id": "JJJ1_YEAST", "id": "P53863-1", "name": "J protein JJJ1", "aln": "-------------------------------------------------------------------------------MKTCYYELLGVETHASDLELKKAYRKKALQYHPDKNPDNVEEATQKFAVIRAAYEVLSDPQERAWYDSHKEQILNDTPPSTDDYYDYEVDATVTGVTTDELLLFFNSALYTKIDNSAAGIYQIAGKIFAKLAKDEILSGKRLGKFSEYQDDVFEQDINSIGYLKACDNFINKTDKLLYPLFGYSPTDYEYLKH-FYKTWSAFNTLKSFSWKDEYMYSKNYDRRTKREVNRRNEKARQQARNEYNKTVKRFVVFIKKLDKRMKEGAKIAEEQ----RKLKEQQRKNELNNRRKFGNDNNDEEKFHLQSWQTVKEENWDELEKVYDNFGEFENSKNDKEGE----------------------VLIYECFICNKTFKSEKQLKNHINTKLHKKNMEEIRKEMEEENITLGLDNLSDLEKFDSADESVKEKEDIDLQALQAELAEIERKLAESSSEDESEDDNLNIEMDIEVEDVSSDENVHVNTKNKKKRKKKKKAKVDTETEESESFDDTKDKRSNELDDLLASLGDKGLQTDDDEDWSTKAKKKKGKQPKKNSKSTKSTPSLSTLPSSMSPTSAIEVCTTCGESFDSRNKLFNHVKIAGHAAVKNV--------VKRKKVKTKRI-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:** * :. .*.: ::*.**** **::***** *. :* ::* :*: **:********:***.*:* :*.. . ::. :*. : *. .:. *:* : :* :..:: . * ** * :.*: : ** *.:: * *.: * * : :* * :::. :* : **:* *: *:.:* *::* * *:: :: **: *: *::: .: : ..:. : .: . . : : ::. :: * * *:*:**. * ** ::* *.: : : :::***: : : . ... * : : .. .: . : : . . . . . . * * : : *.. . . . *.** * ::**** *:* :.*. * . :: ", "identical_positions": 101, "similar_positions": 147, "identity": "14.33%" }, { "cls_id": "homologset.agr.SGD:S000005173", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VGA1-1", "uniprot_id": "Q9VGA1_DROME", "id": "Q9VGA1-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------MDLYYRPGSAPCRSVLMTAKALGVEFDKKTIINTRAREQFTPEYLKINPQHTIPTLHDH---GFALWESRAIMVYLVEKYGKDDK---LFPKDVQKQALINQRLYFDMGTLYKSFSEYYYPQIFL----KKPAN--EENYKKIEVAFEF-----LNTFLEGQTYSAGGDYSLADIAFLATVS-TFDVAGFDFKRYANVARWYENAKKLTP---GWEENWAGCQEFRKYFDN------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20432-1", "uniprot_id": "GSTD1_DROME", "id": "P20432-1", "name": "Glutathione S-transferase D1", "aln": "----------------------------------------------------------------------------------------------------------------MVDFYYLPGSSPCRSVIMTAKAVGVELNKK-LLNLQAGEHLKPEFLKINPQHTIPTLVDN---GFALWESRAIQVYLVEKYGKTDS---LYPKCPKKRAVINQRLYFDMGTLYQSFANYYYPQVFA----KAPAD--PEAFKKIEAAFEF-----LNTFLEGQDYAAGDSLTVADIALVATVS-TFEVAKFEISKYANVNRWYENAKKVTP---GWEENWAGCLEFKKYFE-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGA0-1", "uniprot_id": "Q9VGA0_DROME", "id": "Q9VGA0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------MLDFYYMLYSAPCRSILMTARALGLELNKK-QVDLDAGEHLKPEFVKINPQHTIPTLVDD---GFAIWESRAILIYLAEKYDKDGS---LYPKDPQQRAVINQRLFFDLSTLYQSYVYYYYPQLFEDV--KKPAD--PDNLKKIDDAFAM-----FNTLLKGQQYAALNKLTLADFALLATVS-TFEISEYDFGKYPEVVRWYDNAKKVIP---GWEENWEGCEYYKKLYLGAILNKQ------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG92-1", "uniprot_id": "Q9VG92_DROME", "id": "Q9VG92-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------MDFYYHPCSAPCRSVIMTAKALGVDLNMK-LLKVMDGEQLKPEFVKLNPQHCIPTLVDD---GFSIWESRAILIYLVEKYGADDS---LYPSDPQKKAVVNQRLYFDMGTLFQSFVEAIYPQIRN----NHPAD--PEAMQKVDSAFGH-----LDTFLEDQEYVAGDCLTIADIALLASVS-TFEVVDFDIAQYPNVARWYENAKEVTP---GWEENWDGVQLIKKLVQERNE---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG98-1", "uniprot_id": "GSTD2_DROME", "id": "Q9VG98-1", "name": "Glutathione S-transferase D2", "aln": "-----------------------------------------------------------------------------------------------------------------MDFYYMPGGGGCRTVIMVAKALGLELNKK-LLNTMEGEQLKPEFVKLNPQHTIPTLVDN---GFSIWESRAIAVYLVEKYGKDDY---LLPNDPKKRAVINQRLYFDMGTLYESFAKYYYPLFRT----GKPGS--DEDLKRIETAFGF-----LDTFLEGQEYVAGDQLTVADIAILSTVS-TFEVSEFDFSKYSNVSRWYDNAKKVTP---GWDENWEGLMAMKALFDARKLAAK------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG95-1", "uniprot_id": "GSTD5_DROME", "id": "Q9VG95-1", "name": "Glutathione S-transferase D5", "aln": "-----------------------------------------------------------------------------------------------------------------MDFYYSPRGSGCRTVIMVAKALGVKLNMK-LLNTLEKDQLKPEFVKLNPQHTIPTLVDN---GFSIWESRAIAVYLVEKYGKDDT---LFPKDPKKQALVNQRLYFDMGTLYDSFAKYYYPLFHT----GKPGS--DEDFKKIESSFEY-----LNIFLEGQNYVAGDHLTVADIAILSTVS-TFEIFDFDLNKYPNVARWYANAKKVTP---GWEENWKGAVELKGVFDARQAAAKQ-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG96-1", "uniprot_id": "GSTD4_DROME", "id": "Q9VG96-1", "name": "Glutathione S-transferase D4", "aln": "-----------------------------------------------------------------------------------------------------------------MDFYYSPRSSGSRTIIMVAKALGLELNKK-QLRITEGEHLKPEFLKLNPQHTIPTLVDN---GFAIWESRAIAVYLVEKYGKDDS---LFPNDPQKRALINQRLYFDMGTLHDSFMKYYYPFIRT----GQLGN--AENYKKVEAAFEF-----LDIFLEGQDYVAGSQLTVADIAILSSVS-TFEVVEFDISKYPNVARWYANAKKITP---GWDENWKGLLQMKTMYEAQKASLK------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG97-1", "uniprot_id": "GSTD3_DROME", "id": "Q9VG97-1", "name": "Inactive glutathione S-transferase D3", "aln": "---------------------------------------------------------------------------------------------------------------------------------MVGKALGLEFNKK-IINTLKGEQMNPDFIKINPQHSIPTLVDN---GFTIWESRAILVYLVEKYGKDDA---LYPKDIQKQAVINQRLYFDMALMYPTLANYYYKAFTT----GQFGS--EEDYKKVQETFDF-----LNTFLEGQDYVAGDQYTVADIAILANVS-NFDVVGFDISKYPNVARWYDHVKKITP---GWEENWAGALDVKKRIEEKQNAAK------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG94-1", "uniprot_id": "GSTD6_DROME", "id": "Q9VG94-1", "name": "Glutathione S-transferase D6", "aln": "-----------------------------------------------------------------------------------------------------------------MDLYNMSGSPSTRAVMMTAKAVGVEFNSI-QVNTFVGEQLEPWFVKINPQHTIPTLVDN---LFVIWETRAIVVYLVEQYGKDDS---LYPKDPQKQALINQRLYFDMGTLYDGIAKYFFPLLRT----GKPGT--QENLEKLNAAFDL-----LNNFLDGQDYVAGNQLSVADIVILATVS-TTEMVDFDLKKFPNVDRWYKNAQKVTP---GWDENLARIQSAKKFLAENLIEKL------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG93-1", "uniprot_id": "GSTD7_DROME", "id": "Q9VG93-1", "name": "Glutathione S-transferase D7", "aln": "--------------------------------------------------------------------------------------------------------------MPNLDLYNFPMAPASRAIQMVAKALGLELNSK-LINTMEGDQLKPEFVRINPQHTIPTLVDN---GFVIWESRAIAVYLVEKYGKPDSP--LYPNDPQKRALINQRLYFDMGTLYDALTKYFFLIFRT----GKFGD--QEALDKVNSAFGF-----LNTFLEGQDFVAGSQLTVADIVILATVS-TVEWFSFDLSKFPNVERWLKNAPKVTP---GWEQNLESLQQGKKFLQDLQAAKEKEVKA-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B7Z0S9-1", "uniprot_id": "B7Z0S9_DROME", "id": "B7Z0S9-1", "name": "", "aln": "-----------------------------------------------------------------------------------------MSDTKRIVTEFVYCLLLRGGKMSPPVLYYLPPSPPCRSILLLAKMLDIDFELK-IVNILEGEQLKPDFVAMNPQHCVPTMNDE---GLVLWESRAILSYLVAAYGKSDQ---LYPTDIRVRALVDQRLQFDLGTLYMRLTDYYFPTMFI----GAPLD--EGKRAKLAEAVGW-----LNTILEGRQFSAADHFTIADLTLLVTVS-QLEAFEFELRPYKHIRQWLDRCKDHMA---PFDYEELNANKANMLADMFKAKMNQSAG--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1ZB72-1", "uniprot_id": "A1ZB72_DROME", "id": "A1ZB72-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------MPKLILYGLEASPPVRAVKLTLAALEVPYEFV-EVNTRAKENFSEEFLKKNPQHTVPTLEDD---GHYIWDSHAIIAYLVSKYGKTDS---LYPKDLLQRAVVDQRLHFESGVIFANALRSITKPLFAGK--QTMIP--KERYDAIIEVYDF-----LEKFLAGNDYVAGNQLTIADFSIISTVSSLEVFVKVDTTKYPRIAAWFKRLQKLPY---YEEANGNGARTFESFIREYNFTFASN----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1ZB70-1", "uniprot_id": "A1ZB70_DROME", "id": "A1ZB70-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------MVKLTLYGVNPSPPVRAVKLTLAALQLPYEFV-NVNISGQEQLSEEYLKKNPEHTVPTLEDD---GNYIWDSHAIIAYLVSKYADSDA---LYPRDLLQRAVVDQRLHFETGVVFANGIKAITKPLFFNG--LNRIP--KERYDAIVEIYDF-----VETFLAGHDYIAGDQLTIADFSLISSITSLVAFVEIDRLKYPRIIEWVRRLEKLPY---YEEANAKGARELETILKSTNFTFAT-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1ZB69-1", "uniprot_id": "A1ZB69_DROME", "id": "A1ZB69-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------MGKISLYGLDASPPTRACLLTLKALDLPFEFV-FVNLFEKENFSEDFSKKNPQHTVPLLQDD---DACIWDSHAIMAYLVEKYAPSDE---LYPKDLLQRAKVDQLMHFESGVIFESALRRLTRPVLFFG--EPTLP--RNQVDHILQVYDF-----VETFLDDHDFVAGDQLTIADFSIVSTITSIGVFLELDPAKYPKIAAWLERLKELPY---YEEANGKGAAQFVELLRSKNFTIVS-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1ZB68-1", "uniprot_id": "A1ZB68_DROME", "id": "A1ZB68-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------MGKLTLYGIDGSPPVRSVLLTLRALNLDFDYK-IVNLMEKEHLKPEFLKINPLHTVPALDDN---GFYLADSHAINSYLVSKYGRNDS---LYPKDLKKRAIVDQRLHYDSSVVTSTG-RAITFPLFWEN--KTEIP--QARIDALEGVYKS-----LNLFLENGNYLAGDNLTIADFHVIAGLTGFFVFLPVDATKYPELAAWIKRIKELPY---YEEANGSRAAQIIEFIKSKKFTIV------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9XYZ9-1", "uniprot_id": "Q9XYZ9_DROME", "id": "Q9XYZ9-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------MSKPALYYATLSPPSRAVLLTAKAIGLDLELR-PINLLKGEHLTPEFLKLNPQHTIPTLIDG---EATIIDSHAICAYLVEKYGQKEQQ--LYPKELVQRANVDARLHLDSGHLFARL-RFLYEPILYYG--STDCS--IDKIAYIQKCWEI-----LEGFLKDQPYLCGSDLTIADFCAVATVTSVNDTAPIDEFKFPKMHAWLKRLAELPY---YQEVNGDGADELKSIFKAKLAENRGK----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7JYX0-1", "uniprot_id": "GSTEE_DROME", "id": "Q7JYX0-1", "name": "Glutathione S-transferase E14", "aln": "------------------------------------------------------------------------------------------------------------MSQPKPILYYDERSPPVRSCLMLIKLLDIDVELR-FVNLFKGEQFQKDFLALNPQHSVPTLVHG---DLVLTDSHAILIHLAEKFDEGGS---LWPQEHAERMKVLNLLLFECSFLFRRDSDFMSATVRQGF--ANVDV--AHHERKLTEAYII-----MERYLENSDFMAGPQLTLADLSIVTTLS--TVNLMFPLSQFPRLRRWFTAMQQLD----AYEANCSGLEKLRQTMESVGSFQFPSSSAVVTEKVE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q64471-1", "uniprot_id": "GSTT1_MOUSE", "id": "Q64471-1", "name": "Glutathione S-transferase theta-1", "aln": "---------------------------------------------------------------------------------------------------------------MVLELYLDLLSQPCRAIYIFAKKNNIPFQMH-TVELRKGEHLSDAFARVNPMKRVPAMMDG---GFTLCESVAILLYLAHKYKVPDH---WYPQDLQARARVDEYLAWQHTGLRRSCLRALWHKVMFPVFLGEQIP--PETLAATLAELDVNLQVLEDKFLQDKDFLVGPHISLADLVAITELMHPVGGGCPVFEGHPRLAAWYQRVEAAVGK-DLFREAHEVILKVKDCPPADLIIKQKLMPRVLAMIQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23202-1", "uniprot_id": "URE2_YEAST", "id": "P23202-1", "name": "Transcriptional regulator URE2", "aln": "MMNNNGNQVSNLSNALRQVNIGNRNSNTTTDQSNINFEFSTGVNNNNNNNSSSNNNNVQNNNSGRNGSQNNDNENNIKNTLEQHRQQQQAFSDMSHVEYSRITKFFQEQPLEGYTLFSHRSAPNGFKVAIVLSELGFHYNTI-FLDFNLGEHRAPEFVSVNPNARVPALIDHGMDNLSIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQTSGHAPMIGQALHFRYFHSQKIASAVERYTDEVRRVYGVVEMALAERREALVMELDTENAAAYSAGTTPMSQSRFFDYPVWLVGDKLTIADLAFVPWNNVVDRIGINIKIEFPEVYKWTKHMMRRPAVIKALRGE-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : :: : ** :* : . : :: ** :*. : . : : : : : : : . : ", "identical_positions": 6, "similar_positions": 26, "identity": "1.66%" }, { "cls_id": "homologset.agr.SGD:S000005174", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CB77-1", "uniprot_id": "ELOA1_MOUSE", "id": "Q8CB77-1", "name": "Elongin-A", "aln": "-MAAESALQVVEKLQARLAAN-PDPKKLLKYLKKLSILPITVDILVETGVGKTVNSFRKH-EQVGNFARDLVAQWKKLVPVERNSEAEDQDFEKNNSRKRPRDALQREEELEGNYQESWKPSGSRSYSPEHRQKKHKKLSEPERPHKVAHSHEKRDERKRCHKVSPPYSSDPESSDYGHVQSPPPS-SPHQMYTDLSRSPEEDQEPIISHQKPGKVHSNTFQDRLGVS---HLGE-QGKGAVSHHKQHRSSHKEKHPADAREDEKISAVSREKSHKASSKEESRRLLSGDSAKEKLPSSVVKKDKDREGSSLKKKFSPALDVASDNHFKKPKHKDSEKAKSDKNKQSVDGVDSGRGTGDPLPKAKEKVPNHLKAQEGKVRTNADGKSAGPLHPKAEETDVDDEFERPTMSFESYLSYDQPRKKKKKVVKTSSTALGEKGLKKKDSKSTSKNLNSAQKLPKVNENKSEKLQPAGAEPTRPRKVPTDVLPALPDIPLPAIHANYRPLPS----LELIPSFQPKRKAFSSPQEEEEAGFTG--RRMNSKMQVYSGSKCAYLPKMMTLHQQCIRVLKNNIDSIFEVGGVPYSVLEPVLERCTPDQLYRIEECNHVLIEETDQLWKVHCHRDFKEERPEEYESWREMYLRLQDAREQRLRLLTNNIRSAHAN-KPKGRQAKMAFVNSVAKPPRDVRRRQEKFGTGGAAVPEKVRIKPAPYTTGSSHVPASNSSSNFHSSPEELAYDGPSTSSAHLAPVASSSVSYDPRKPAVKKIAPMMAKTIKAFKNRFSRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63187-1", "uniprot_id": "ELOA1_RAT", "id": "Q63187-1", "name": "Elongin-A", "aln": "-MAAESALQVVEKLQARLAAN-PDPKKLLKYLKKLSVLPITVDILVETGVGKTVNSFRKH-EQVGNFARDLVAQWKKLVPVERNNEAEDQDFEKSNSRKRPRDVPQQEEEAEGNYQESWQASGSQPYSPEHRQKKHRKLPELERPHKVAHGHERRDERKRCHKVSPPYSSDPESSDYGHVQSPPPS-SPHQMYTDLSRSPEMDQEPIVSHPKPGKVHSNTFQDRLGVS---HLGEHQGKGAVSQNKPHKSSHKEKRPVDARGDEKSSVMGREKSHKASSKEESRRLLSEDSAKEKLPSSVVKKEKDREGNSLKKKLSPALDVASDNHFKKPKHKDSEKIKSDKNKQSVDSVDSGRGTGDPLPRAKDKVPNNLKAQEGKVRTNSDRKSPGSL-PKVEEMDMDDEFEQPTMSFESYLSYDQPRKKKKKVVKTSGTALGEKGLKKKDSKSTSKNLNSAQKLPKANENKSDKLQPAGAEPTRPRKVPTDVLPALPDIPLPAIQTNYRPLPS----LELISSFQPKRKAFSSPQEEEEAGFTG--RRMNSKMQVYSGSKCAYLPKMMTLHQQCIRVLKNNIDSIFEVGGVPYSVLEPVLERCTPDQLYRIEECNHVLIEETDQLWKVHCHRDFKEERPEEYESWREMYLRLQDAREQRLRLLTNNIRSAHAN-KPKGRQAKMAFVNSVAKPPRDVRRRQEKFGTGGAAVPEKVRIKPAPYTTGSSHVPASNSSSSFHSSPEELAYEGPSTSSAHLAPVASSSVSYDPRKPAVKKIAPMMAKTIKAFKNRFSRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14241-2", "uniprot_id": "ELOA1_HUMAN", "id": "Q14241-2", "name": "Elongin-A", "aln": "-MAAESALQVVEKLQARLAAN-PDPKKLLKYLKKLSTLPITVDILAETGVGKTVNSLRKH-EHVGSFARDLVAQWKKLVPVERNAEPDEQDFEKSNSRKRPRDALQKEEEMEGDYQETWKATGSRSYSPDHRQKKHRKLSELERPHKVSHGHERRDERKRCHRMSPTYSSDPESSDYGHVQSPPSCTSPHQMYVDHYRSLEEDQEPIVSHQKPGKGHSNAFQDRLGASQERHLGEPHGKGVVSQNKEHKSSHKDKRPVDAKSDEKASVVSREKSHKALSKEENRRPPSGDNAREKPPSSGVKKEKDREGSSLKKKCLPPSEAASDNHLKKPKHRDPEKAKLDKSKQGLDSFDTGKGAGDLLPKVKEKGSNNLKTPEGKVKTNLDRKSLGSL-PKVEETDMEDEFEQPTMSFESYLSYDQPRKKKKKIVKTSATALGDKGLKKNDSKSTGKNLDSVQKLPKVNKTKSE--KPAGADLAKLRKVP-DVLPVLPDLPLPAIQANYRPLPS----LELISSFQPKRKAFSSPQEEEEAGFTG--RRMNSKMQVYSGSKCAYLPKMMTLHQQCIRVLKNNIDSIFEVGGVPYSVLEPVLERCTPDQLYRIEEYNHVLIEETDQLWKVHCHRDFKEERPEEYESWREMYLRLQDAREQRLRVLTKNIQFAHAN-KPKGRQAKMAFVNSVAKPPRDVRRRQEKFGTGGAAVPEKIKIKPAPYPMGSSHASAS--SISFNPSPEEPAYDGPSTSSAHLAPVVSSTVSYDPRKPTVKKIAPMMAKTIKAFKNRFSRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VCP0-1", "uniprot_id": "ELOA1_DROME", "id": "Q9VCP0-1", "name": "Transcription elongation factor B polypeptide 3", "aln": "MASTSNLLDVVRHYQRSIEKHGEDEQRLLHCITKLFNLPIKFEHLQETGIGKTVNALRKISGEVGVAAKTLVTKWKAMVAKEDPSIASTPTAIHNEEDSGKTKSSDEDPDQE---NKGGNSSSGEDLNTSKHKSKHAKSTKHERSSSSRSHSKSRSDSDKKHKSSRHDKSKDRDKDR---------------------------------------------------------EGQKEAKEHKEKKSNGEHKSKDSSKSSSSHKSSKSESHKSEHTKSKHEKDKTSHSELKEVKDKSS---KHKSSSSKSSKRSHSPPRHEEESQKAKIP------KVKSKSEEDSADGFDSSMGAN------FDDVLGLLNIPISSKKSSSNSKS--------------------------------------KFVAKPTAAPSSSALSAPTTAGSSKEALSTSSRPTSKK-----------PELLASTAKLEPLDPNIALELPTISNNYKPMPLNQTVMDVVFNQGGSHKAQASRYFNESEALAQGISSKTMRTKIYSGVRTGQILQVPSLFDLCTRVLQKNIDALEYTGGVPFEVLRPVLERATPQQLLNFEEYNPYLMDDSDVLWQQHVQRHCRSQRREEMETWREMFLRCQEEKDRKLSILAESIKASQKISEAPVRKTQLAFVDSMVKPPRSVQRKQEQYGTKGKLIATPAARVAALSSVTPNAAKVGDARLRVLAAARDTAQVG--------------------AGPARSKKAPLMAKTLQFMRGRLKR-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53861-1", "uniprot_id": "ELOA1_YEAST", "id": "P53861-1", "name": "Elongin-A", "aln": "---MKSLQTLCEISLMRNHSNIQSVSNVPYHLLKRILQKVKIPQLLKLEKSNVLLIFDDD------------ELWLEFLRQDFPTNVHEQFVSK-------------------------------------RDIICKYYFDFVKENDIELYHSNQDLLKSCVR-------------------------------------------------------------------------QSVVKDIRNNKYRIPYRMLYSKYQQEVEKKQEESAERLRLEMQKLQQER--EKKQTIVVDHTVYFKKRNTKKTTRLHNEPHSQLYMKS-----------------------------------------------LKDHESRLKHFKDG--------------------------------------GFNIAKRHAQRVAFGGQAGGQSSSPKKGPLSIKPEP--------------------------------------------------------------------------------------------------------------VKVNRQMDNVTAEK-------KDVTQPITPVKKRRSESPSIFLNRKKPALFRPTPKTNAAGSRP-------------------HTTAITNDHRTTSHP---YPHKDVVTSISSVTANPVTKGHKKKKSGIFVRNAGSDGDSFPHVTATGPTTRPYIYEPRK----------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : . : . ..: : * :.. * : .:.: : . * :: : : :. . : . . :. . : : :.: . :: . .* . .: . .* :. : . : * : . . :.. . . *: . : : :.. . . : .. * * . * ::.::* : . * : ** : . *. . * .. *:: : . .* : :::. : : :: :: :.*:. * ::::: * . . .. ", "identical_positions": 21, "similar_positions": 117, "identity": "2.66%" }, { "cls_id": "homologset.agr.SGD:S000005175", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6JFQ6-1", "uniprot_id": "CLVS1_RAT", "id": "A6JFQ6-1", "name": "Clavesin-1", "aln": "--MGPVSVLPKPQSISTWEGDLAKMTHLQAG--------LSPDTIEKARLELNENPD--VLHQDIQQVRDMIITRPDIG----------FLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFKNFKADDPGIKRALIDGFPG---VLENRDHYGRKILLLFAAN-WDQSRNSFTDILRAILLSLEVLIEDPEL----------------QINGFILIIDWSNFS-----FKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNN-LNSLHQLIHPEFLPSEFGGTLP-PYDMGTWARTLLGPDYSDENDYTHTSYNAMYVKHTCSNLERECSPKPMKRSQSVVEAGTLKHEE--KGENENTQPLLALD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D4C9-1", "uniprot_id": "CLVS1_MOUSE", "id": "Q9D4C9-1", "name": "Clavesin-1", "aln": "--MGPVSVLPSPQSLSTWEGDLAKMTHLQAG--------LSPDTIEKARLELNENPD--ILHQDIQQVRDMIITRPDIG----------FLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFKNFKADDPGIKRALIDGFPG---VLENRDHYGRKILLLFAAN-WDQSRNSFTDILRAILLSLEVLIEDPEL----------------QINGFILIIDWSNFS-----FKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNN-LNSLHQLIHPEFLPSEFGGTLP-PYDMGTWARTLLGPDYSDENDYTHTSYNAMHVKHTCSNLERECSPKPMKRSQSVVEAGTLKHEE--KGENENTQPLLALD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IUQ0-1", "uniprot_id": "CLVS1_HUMAN", "id": "Q8IUQ0-1", "name": "Clavesin-1", "aln": "--MGPVSLLPKYQKLNTWNGDLAKMTHLQAG--------LSPETIEKARLELNENPD--VLHQDIQQVRDMIITRPDIG----------FLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFKNFKADDPGIKRALIDGFPG---VLENRDHYGRKILLLFAAN-WDQSRNSFTDILRAILLSLEVLIEDPEL----------------QINGFILIIDWSNFS-----FKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNN-LNSLHQLIHPEFLPSEFGGTLP-PYDMGTWARTLLGPDYSDENDYTHTSYNAMHVKHTSSNLERECSPKLMKRSQSVVEAGTLKHEE--KGENENTQPLLALD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SYC1-1", "uniprot_id": "CLVS2_HUMAN", "id": "Q5SYC1-1", "name": "Clavesin-2", "aln": "------------------------MTHLQAG--------LSPETLEKARLELNENPD--TLHQDIQEVRDMVITRPDIG----------FLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPG---GLANLDHYGRKILVLFAAN-WDQSRYTLVDILRAILLSLEAMIEDPEL----------------QVNGFVLIIDWSNFT-----FKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNN-LNSLHQLIHPEILPSEFGGMLP-PYDMGTWARTLLDHEYDDDSEYNVDSY-SMPVK----EVEKELSPKSMKRSQSVVDPTVLKRMD--KNEEENMQPLLSLD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6JUQ6-1", "uniprot_id": "CLVS2_RAT", "id": "A6JUQ6-1", "name": "Clavesin-2", "aln": "------------------------MTHLQAG--------LSPETLEKARLELNENPD--TLHQDIQEVRDMVITRPDIG----------FLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPG---GLANLDHYGRKILVLFAAN-WDQSRYTLVDILRAILLSLEAMIEDPEL----------------QVNGFVLIIDWSNFT-----FKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNN-LNSLHQLIHPEILPSEFGGMLP-PYDMGTWARTLLDHEYDDDSEYNVDSY-SMPVN----EVDKELSPKSMKRSQSVVDPTALKRMD--KSEEENMQPLLSLD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG92-1", "uniprot_id": "CLVS2_MOUSE", "id": "Q8BG92-1", "name": "Clavesin-2", "aln": "------------------------MTHLQAG--------LSPETLEKARLELNENPD--TLHQDIQEVRDMVITRPDIG----------FLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPG---GLANLDHYGRKILVLFAAN-WDQSRYTLVDILRAILLSLEAMIEDPEL----------------QVNGFVLIIDWSNFT-----FKQASKLTPNMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNN-LNSLHQLIHPEILPSEFGGMLP-PYDMGTWARTLLDHEYDDDSEYNVDSY-NMPVK----DVDKELSPKSMKRSQSVVDPTALKRMD--KSEEENMQPLLALD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SPP0-1", "uniprot_id": "CLVS2_DANRE", "id": "Q5SPP0-1", "name": "Clavesin-2", "aln": "------------------------MTHLQAG--------LSPETLEKAKVELKENPD--TLHQDIQEVRDMIITRPDIG----------FLRTDDAFILRFLRARKFNHFEAFRLLAQYFEYRQQNLDMFKNLKATDPGIKQALKDGFPG---VLSNLDRYGRKILVLFAAN-WDQSRYTFVDILRAILLSLEAMIEDPEL----------------QVNGFVLIIDWSNFT-----FKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKDKTRKRIFMHGNN-LNSLHQLILPEILPSELGGMLP-PYDMGTWARTLLDHAYDEETDYCPESY-TLSVK----DLEKDLSPKTMKRSQSVVEPGVLKRPEKVKSEEENMQPLLSLD--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Z275-1", "uniprot_id": "RLBP1_MOUSE", "id": "Q9Z275-1", "name": "Retinaldehyde-binding protein 1", "aln": "MSDGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEKEE--TREEAVRELQELVQAQAASGEELALAVAERVQARDSAFLLRFIRARKFDVGRAYELLKGYVNFRLQYPELFDSLSMEA--LRCTIEAGYPG---VLSSRDKYGRVVMLFNIEN-WHCEEVTFDEILQAYCFILEKLLENEET----------------QINGFCIVENFKGFT-----MQQAAGLRPSDLKKMVDMLQDSFPARFKAIHFIHQPWYFTTTYNVVKPFLKNKLLQRVFVHGDD-LDGFFQEIDENILPADFGGTLP-KYDGKVVAEQLFGPRAEVENTAL-----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z956-1", "uniprot_id": "D3Z956_RAT", "id": "D3Z956-1", "name": "Retinaldehyde-binding protein 1", "aln": "MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREE--TRDEAVRELQELVQAQAASGEELAVAVAERVQARDSAFLLRFIRARKFDVGRAYELLKGYVNFRLQYPELFDSLSMEA--LRCTIEAGYPG---VLSSRDKYGRVVMLFNIEN-WHCEEVTFDEILQAYCFILEKLLENEET----------------QINGFCIVENFKGFT-----MQQAAGLRPSDLKKMVDMLQDSFPARFKAIHFIHQPWYFTTTYNVVKPFLKNKLLQRVFVHGDD-LDGFFQEIDENILPADFGGTLP-KYDGKVVAEQLFGPRVEVENTAL-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12271-1", "uniprot_id": "RLBP1_HUMAN", "id": "P12271-1", "name": "Retinaldehyde-binding protein 1", "aln": "MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREE--TREEAVRELQEMVQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNFRLQYPELFDSLSPEA--VRCTIEAGYPG---VLSSRDKYGRVVMLFNIEN-WQSQEITFDEILQAYCFILEKLLENEET----------------QINGFCIIENFKGFT-----MQQAASLRTSDLRKMVDMLQDSFPARFKAIHFIHQPWYFTTTYNVVKPFLKSKLLERVFVHGDD-LSGFYQEIDENILPSDFGGTLP-KYDGKAVAEQLFGPQAQAENTAF-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRP8-1", "uniprot_id": "Q9VRP8_DROME", "id": "Q9VRP8-1", "name": "", "aln": "-------------MVQDQGETTG----------------LPEALLKIAKRELREDRC--TREQSLEQLRNWVAKNEDLQ----------NVRCDDTFLLRFLRAKKFSVPMAEQTLLKYLNIRRTFPHMSTQLDYLEPRLGDLIDQGYIF---AVPQRDKHGRRVVVINAKG-LNPKIHTSCDQAKAHFLTYECLMEDQET----------------QITGLTHVGDFAGVT-----TAHVTNWNPTEFARIFKWGEQSLPMRHKEIHLINVPSTLKWLIDFVKNRVSSKMKNRLIIYGS--EKELMKSVDQGCLPLEMGGKVP-MREMIELWKQELATKRDLILGLD--------------KSILRSDRGIQRRSSFNAGKASTGGPNFVSQIESIEGSFRKLEFD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTY1-1", "uniprot_id": "Q9VTY1_DROME", "id": "Q9VTY1-1", "name": "CRAL-TRIO domain-containing protein", "aln": "---------MLETEVLQQPKLSGPAASSGGDYDYPYVCGLSPAMKLVAKEELHEDEN--IRRQALAQFREWIEKHPHIR----------KCRTDTVFLLRFLRTKKFSVPSACEMLERYLTIRQLFPQWFKQLDINDPAINEIFENGYLV---PLPQRDSTGRQVIFSVAAK-FDPYKFTSVQMARVHSLVCEALLDDEDS----------------QVAGYVYINDESGMN-----MGFVSLWSLTDLRSIVKCIQNSTPMRHKETHFVNIPHYANRIIELGVSMLSDKLKKRIIVHKN--VDILKTKIDPAILPKEYGGTVP-IADMIAQFKQKLQQRRAAILALD--------------DMQIEVTKDAANFAGNDIGDIDAG----------VVGSFRKLEVD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W503-1", "uniprot_id": "Q9W503_DROME", "id": "Q9W503-1", "name": "CRAL-TRIO domain-containing protein", "aln": "-------------------------------------MDKDTGDKDSAPETSASPAT--GWSDKLTDLVAWFEANPNLP-----------EKIEPIVMLRFLKCTAFDVERTKALAELNYCMRNKSPHLFMDRNMEDEMTAEGLRVSDLL---ILPGVTPQGNKLIFFRMAD-LDPRTRNSVEETKIFVMMSDARFTKPDVERETGSGADYVLDEADIAEGDVQIVDIGGYT-----LRHLAYVSIFVLRVYMKFLQEAYPSRLQAMHVINCPTYLDKLISMMSPFLREEVRNMIRYHTEG-MDSLYKEVPRDMLPNEYGGKAGTVAELKAKGIQSIRDNAAYLSDER--------------YWKV-----AAQSKSRWSWF-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W408-1", "uniprot_id": "Q9W408_DROME", "id": "Q9W408-1", "name": "CRAL-TRIO domain-containing protein", "aln": "----------------------------------------------MVHLNEKAEDQ--LMTTRISDLQDWLQAQPQLP-----------QNISRLLLRRFLHTTRGDLSAAQRLLELNYGLRNKHAHIFIDRDPLDASSQQLLQVADLV---PLPGLTPENNKLLFYRLID-FDADKFNFTAAIKVFFMVADCRFATENEERLS--------------DGEIPVFDMAGYT-----LRHLTKTALGALRVYMKFVQEAHPVRLKEIHVLNCPSYVDKVMAVVKPFIKGEVFKLIHFHLPN-ADTPYRHFPRSMLPEEYGGEAGKMSDLKLQWMQLLKEQRDYLMDTE--------------NWQINKIKKNGQRKSSDSGVTEGLRSLEID---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8I099-1", "uniprot_id": "Q8I099_DROME", "id": "Q8I099-1", "name": "CRAL-TRIO domain-containing protein", "aln": "----------------------------------MMMLHPTPDQRVSIREELREPEDPADIERDIKLIREWLETQPHLP-----------KDMDDMRLTTFLRGCKFSLEKVKKKLDMYYTMRNAVPEFFSNRDINREELNIVLDYVHCP---TLPGITPNGRRITFIRGID-CDFQPHHILDAMKVALMIGDVRLAEESVG----------------IAGDIFILDASVAS-----AAHFAKFSPTVVKKFLIAVQEAYPVKVKEVHVINISPLVDTIFNFVKPFVKEKIRSRITFHND--VESLYKVVPRDLLPNEYGGKAGGVVELNQWWKQKLVDNTQWFKDQEDK------------KANESLRPGAPKTSDDLFGMEGTFRQLNID---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9V4-1", "uniprot_id": "Q9V9V4_DROME", "id": "Q9V9V4-1", "name": "CRAL-TRIO domain-containing protein", "aln": "--------------------------------------------MKEANLEDQYASFPEIRRPEVLKFLDWIHAQPHIS-----------DRFSEGEALHFFHACRYSMEVAKQVLDTNLTARTHLEEFFVNLDCERPEIRRAMRTVSIV---PLPGATPEGYRVILAKLDD-LNTSNYNFADVMKLYCMVFDFWMYEDGIQ-----------------PGHVIVIDLKNTS-----LGHVARIGLLQMKKFLYYLQEAAAIRLIGFHFINIVPFMDKILALMTPFMKKELTTVLHMHSD--LKEFYKFVPQEMLPKEYGGQLEEANVAKEIYYKKLLDNRKEMIEFETR-----------HQVNEKLRPGKAKNASDLFGIEGNFKKLDID---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VM12-1", "uniprot_id": "Q9VM12_DROME", "id": "Q9VM12-1", "name": "CRAL-TRIO domain-containing protein", "aln": "---------------MAATDIAEEAFHLRLG-------YLKPETVEIARVELRETEE--VKAEAIIKLRELLKATPELN-----------YKDDDAFLTVFLRACHFYPEGALEKMKTTASFRKEYASLVRG-LLVEQVKEKFVKGSVIN---VLKNCDQKGRRVLIVNCGKLWDPSDITSDEMFRMLYMVHLAAQLEEET----------------QVRGVVCIMDFEGLS-----MKQVKALSPSFSKRLLTFIQEAMPLRMKEVHFVKQPFIFNMVWSLFKPFVKQKLNNRMHFHGSD-MKSLQKFLDPSVLPANYKGTLPAIDYGGVEWFPALEQQAQYVEEWS--------------------QLGPAQW--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VM11-1", "uniprot_id": "Q9VM11_DROME", "id": "Q9VM11-1", "name": "CRAL-TRIO domain-containing protein", "aln": "---------MGKAECISYDEHKLPYIDLGSAQIRMEKEQAPEWALKKAQDELREVPG--VKEQAIKELRELIQNEKYLN-----------LPLDDEYMMMFLRPTHYYPESALKRLKNFYHMKLKYGAACEN--IIPSKLRNVFEANILN---LLPQRDQHGRRLLVLEAGKKWKPSQVPLVDLFRGIQLTVLGSMVEPYS----------------QICGSVVIIDMEGLP-----LSHITQFTPSFAAMLLDYIQECICMRLKAVHIVNNSYIFNMLFAVFKPFIREKLRKRIFFHGKD-YKSLISHIEAKALPPKYGGSATWELPHGKVLGEFFECYSKDYELAD----------------SYGYTEGYKMKK-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VD09-1", "uniprot_id": "PINTA_DROME", "id": "Q9VD09-1", "name": "Retinol-binding protein pinta", "aln": "---------------------------------------MWSRSSSSKRQVATTDGDPERVLAQVQDLSDWLVANPQIN-----------GCNTFENLHFFLRTSKFDVERAKKKLKTFYQMRAERTEWFDNRDPQLPEIQDLLKLGVFL---PIGPDAEQRMVVVIRTAAH--DPKLHSQNNVFKTSKMILDLLLKLDPET---------------CARGMVAILDMQGVQ-----LGHALQMNPKLIKRSVES-WTAYPCQPKLLEFTNAPRHVNFFLNTFRIFMTPKIRSRLFVRRE------GTSVSCDQLPKELGGQGLSYMELSVKWKQLVEENADFYVEQD-------------------------KYKSKLK---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJN4-1", "uniprot_id": "Q9VJN4_DROME", "id": "Q9VJN4-1", "name": "CRAL-TRIO domain-containing protein", "aln": "------------------------------------------MLFLTARVDHTAEQI-----FKIEQLRQLVEKCEDLR-----------VGTEDTLLTKFLHYTRWDTIKAYQAIHDYYEFKRRHPTWVAR-HPIEHYRQLFYGTHCRY---VMPQADRSGRVLVVFKTVDGFQDYPDYLQSLVEMDDLIFESLLLLPRVQ----------------QNGITVICDLQGTN-----RNFLRQFSP-AFMKVVNEKNGVLPFSQRIVHIIQRGFLMHVTSTLFMPFMNKEFKEKIFTHDGRHLSKLREMVGYESLPAEYGGPATNVLDTNLIFN-HLSQNAEYLEKLQT----------------------YGKA--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53860-1", "uniprot_id": "PDR16_YEAST", "id": "P53860-1", "name": "Phosphatidylinositol transfer protein PDR16", "aln": "--------MFKRFSKKKEAPEDPKNLINIDKPIKELPASIAIPKEKPLTGEQQKMYDEVLKHFSNPDLKVYTSEKNKSEDDLKPLEEEEKAWLTRECFLRYLRATKWVLKDCIDRITMTLAWRREFGISHLGEEHGDKITADLVAVENESGKQVILGYENDARPILYLKPGR---QNTKTSHRQVQHLVFMLERVIDFMPAG----------------QDSLALLIDFKDYPDVPKVPGNSKIPPIGVGKEVLHILQTHYPERLGKALLTNIPWLAWTFLKLIHPFIDPLTREKLVFDEP-----FVKYVPKNELDSLYGGDLKFKYNHDVYWPALVETAREKRDHYFKR--------------FQSFGGIVGLSEVDLRGTHEKLLYPVKSESSTV----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::: : : : . : . : : . . : : : . * * . ", "identical_positions": 2, "similar_positions": 19, "identity": "0.49%" }, { "cls_id": "homologset.agr.SGD:S000005176", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RDC9-1", "uniprot_id": "M0RDC9_RAT", "id": "M0RDC9-1", "name": "Exosome complex component CSL4", "aln": "MAPP---VRYCIPGERLCNLEEG------------SPGSGT----YTRHG----YIFSSLAGCLTKTSENGALP--------------------------------VVSVMR-------------ETESQLLPDVGAVVTCKVSSINSRFAKVHILYVG----------------------------------STPLKNAFRGTIRKEDIRATEKDKVEIYKSFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHS----ESGVQMVPISWCEMQCPKTHTKEFRKVARVQPEFLQT---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAA6-1", "uniprot_id": "EXOS1_MOUSE", "id": "Q9DAA6-1", "name": "Exosome complex component CSL4", "aln": "MAPP---VRYCIPGERLCNLEEG------------SPGSGT----YTRHG----YIFSSLAGCLMKTSENGAVP--------------------------------VVSVMR-------------ETESQLLPDVGAVVTCKVSSINSRFAKVHILYVG----------------------------------STPLKNAFRGTIRKEDIRATEKDKVEIYKSFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHS----ESGVQMVPISWCEMQCPKTHTKEFRKVARVQPEFLQT---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3B2-1", "uniprot_id": "EXOS1_HUMAN", "id": "Q9Y3B2-1", "name": "Exosome complex component CSL4", "aln": "MAPP---VRYCIPGERLCNLEEG------------SPGSGT----YTRHG----YIFSSLAGCLMKSSENGALP--------------------------------VVSVVR-------------ETESQLLPDVGAIVTCKVSSINSRFAKVHILYVG----------------------------------SMPLKNSFRGTIRKEDVRATEKDKVEIYKSFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHS----ESGIQMVPISWCEMQCPKTHTKEFRKVARVQPEFLQT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKJ4-1", "uniprot_id": "Q9VKJ4_DROME", "id": "Q9VKJ4-1", "name": "", "aln": "MSEQQDETVVCLPGERLCRTEDSI-----------VLGIGT----YEQNG----YIYASKSGIVNIEDSGDKCQ--------------------------------VVSVHK-------------PGFHLTIPATGDVVTARVLVTTPKFAKCAIFCVR----------------------------------NVLLESSYRGLLRKEDVRETEKDRVDIYKSFRPGDVILARVIN--QLEQSFLLTTAENELGVVIAYASDYRKTRVPMVPVGWSEMQCPQTTIKEPRKVAKVLPESSINAVK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53859-1", "uniprot_id": "CSL4_YEAST", "id": "P53859-1", "name": "Exosome complex component CSL4", "aln": "MACNFQFPEIAYPGKLICPQYGTENKDGEDIIFNYVPGPGTKLIQYEHNGRTLEAITATLVGTVRCEEEKKTDQEEEREGTDQSTEEEKSVDASPNDVTRRTVKNILVSVLPGTEKGRKTNKYANNDFANNLPKEGDIVLTRVTRLSLQRANVEILAVEDKPSPIDSGIGSNGSGIVAAGGGSGAATFSVSQASSDLGETFRGIIRSQDVRSTDRDRVKVIECFKPGDIVRAQVLSLGDGTN-YYLTTARNDLGVVFARAAN--GAGGLMYATDWQMMTSPVTGATEKRKCAKPF---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . **: :* * ** * ::* * :: * : .. :*** :* * :* :* . : *: *: * . * .::** :*.:*:* *::*:*.: :.*:***:: *:*:. : . : ****.*:****.* : : * . .* * .* * .* ** *: ", "identical_positions": 55, "similar_positions": 53, "identity": "18.09%" }, { "cls_id": "homologset.agr.SGD:S000005177", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6RFY2-1", "uniprot_id": "PHAR3_RAT", "id": "Q6RFY2-1", "name": "Phosphatase and actin regulator 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDQTPPARSEPLVSGIRTPPVRRNSKLATLGRIFKPWKWR-KKKNEKLKQTTSALEKKMAGRQGREELIKQGLLEMMEQDSESKACSPKEGSQPAQSEPSAGEQETLTSEGVQPGSPSASGTDQASQDE-LLSSDAHPDDTAKMSSASSGEEADAGNLLPTTDEPSQE--------------------------------------------------------------------ALSG--SLDSPPRT----LERSASQLP----------------SPPLLPTPPPK----ASSKATKNVTGQAALFQGSSMKNNEPVLRGQLPTPTGSPHLTTVHRPLPPS--------------------------------------------------------------------------------------------------------------------------------------------------------------------RVIEELHRALATKHRQDSFQGRECRGSPKKRMDVRLSRTSSMERGKERDEAWS------------------------------------------FDGASENKWTAAKDSEENKENLILSSELKDD-----------------------------------------------LLLYQDEEA-------LNDSIISGTLP-RKCKKELLAVKLRNRPSKQE--------------LEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERR-------NILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVARAQ---DYDRRADKP-WTRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BYK5-1", "uniprot_id": "PHAR3_MOUSE", "id": "Q8BYK5-1", "name": "Phosphatase and actin regulator 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MAASEDGSSCLVSRGRSQSDPSFLSDSSATS-TDAGENPDE-------------------------------------------------------------------------------------MDQTPPARSEPLVSGIRTPPVRRNSKLATLGRIFKPWKWR-KKKNEKLKQTTSALEKKMAGRQGREELIKQGLLEMMEQDSENKACSPKEGSQPVQSEPPAGEQETLTSEGAQPGSPSASGTDQVSQDE-LLSSDAHLDDTANIPSASTAEEADAGSLLPTTDEPSQ---------------------------------------------------------------------ALAGSDSLDSPPRS----LERSVSQLP----------------SPPLLPTPPPK----ASSKATKNVTGQAALFQGPSMKNNEPALRGQLATPTGSPHVTTVHRPLPPS--------------------------------------------------------------------------------------------------------------------------------------------------------------------RVMEELHRALATKHRQDSFQGRECRGSPKKRMDVRLSRTSSMERGKERDEAWS------------------------------------------FDGASENKWTATKDSEENKENLMLSSELKDD-----------------------------------------------MLLYQDEEA-------LNDSIISGTLP-RKCKKELLAVKLRNRPSKQE--------------LEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERR-------NILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVARAQ---DYDRRADKP-WTRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96KR7-1", "uniprot_id": "PHAR3_HUMAN", "id": "Q96KR7-1", "name": "Phosphatase and actin regulator 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MAASEDGSGCLVSRGRSQSDPSVLTDSSATSSADAGENPDE-------------------------------------------------------------------------------------MDQTPPARPEYLVSGIRTPPVRRNSKLATLGRIFKPWKWR-KKKNEKLKQTTSALEKKMAGRQGREELIKKGLLEMMEQDAESKTCNPDGGPRSVQSEPPTPKSETLTSEDAQPGSPLATGTDQVSLDK-PLSSAAHLDDAAKMPSASSGEEADAGSLLPTTNELSQ---------------------------------------------------------------------ALAGADSLDSPPRP----LERSVGQLP----------------SPPLLPTPPPK----ASSKTTKNVTGQATLFQASSMKSADPSLRGQLSTPTGSPHLTTVHRPLPPS--------------------------------------------------------------------------------------------------------------------------------------------------------------------RVIEELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWS------------------------------------------FDGALENKRTAAKESEENKENLIINSELKDD-----------------------------------------------LLLYQDEEA-------LNDSIISGTLP-RKCKKELLAVKLRNRPSKQE--------------LEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERR-------NILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQ---DYDRRADKP-WTRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QHN5-1", "uniprot_id": "A0A8M9QHN5_DANRE", "id": "A0A8M9QHN5-1", "name": "Phosphatase and actin regulator", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MAASDGPEDCVVQRGRSQSDPSILTET--------RVVPDV-------------------------------------------------------------------------------------MDQHRALHSGCLVSGVRTPPIRRNSKLASLGRIFKPWKWR-KKKNEKLRQGSTALERKVSSRQNHEDPVRKGLAEAGMVCSDSAVACG--GSADELGNPVMEDSDGDEPEDE-PMAPLASTTEDLGSDEDNLSTVRDAAEMTETEADLGHSEDEDGSAVDAVGPLEAP--------------------------------------------------------------------ESPEEKHEEPAPRE----THTPPAKLP----------------VKLLTRLGSLDGQCQVITRTHSHQSRPAPATLPRNFTLPKDALRGRISTPTGSPHLGLLHPQLPPS--------------------------------------------------------------------------------------------------------------------------------------------------------------------CIIEELHRALATKHRQDSFHSKEIRSSPKRRSDGRLPRVASTENEQ--------------------------------------------------SGEAENK----KEAEENKENMRLD------------------------------------------------------EIYSDQDS-------WNESVISGTLP-RRIRKELLAVKLRNRPSKQE--------------LEDRNIFPVRSDQERQEIRQQIEMKLAKRLSQRPAVEELESR-------NILKQRNDQTEQEERREIKQRLNRKLNQRPTVDELRDRKILIRFSDYVEVAKAQ---DYDRRADKP-WTRLSASDKAAIRKELNEFKSNEMEVHASSKHLTRFHRP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2M3X8-1", "uniprot_id": "PHAR1_MOUSE", "id": "Q2M3X8-1", "name": "Phosphatase and actin regulator 1", "aln": "-----------------------------------------------------------------------------------------------------------------------MDYP---KMDYFLDVESAHRLLDVESAQRFFYSQGAQARRATLLLPPTLMAASSEDD-IDRRPIRRVRSKS-------DTPYLAEARISFNLG-------------------------------------------------------AAEEVERLAAMRSDSLVPGTHTPPIRRRSKFANLGRIFKPWKWR-KKKSEKFKHTSAALERKISMRQSREELIKRGVLKEIYDKDGELS----------------ISNEDDSLENGQS-------LSSSQLSLPALSEMEPVPMPRDPCSYEVLQASDIMDGPDPGAPVKLP--------------------------------------------------------------------CLP---------------VKLSPPLPP----------------KKVLICMPVGGPELTLASYAAQKSSQQAVAQHHHTVLPSQMQHQLQYGSHGQHLPSSTGTLPMHPSG------------------------------------------------------------------------------------------------------------------------------------------------------------------CRMIDELNKTLAMTMQRLESSEQRVPCSTSYHSSGLHSSDGITKAGPMG------------------------------------------------LPEIRQVPTVVIECDDNKENVPHEPDYEDS-----------------------------------------------PCLYGREEEEEEEDEDDDASLYTSSLAMKVCRKDSLAIKLSNRPSKRE--------------LEEKNILPRQTDEERLELRQQIGTKLTRRLSQRPTAEELEQR-------NILKPRNEQEEQEEKREIKRRLTRKLSQRPTVEELRERKILIRFSDYVEVADAQ---DYDRRADKP-WTRLTAADKAAIRKELNEFKSTEMEVHELSRHLTRFHRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62024-1", "uniprot_id": "PHAR1_RAT", "id": "P62024-1", "name": "Phosphatase and actin regulator 1", "aln": "-----------------------------------------------------------------------------------------------------------------------MDYP---KMDYFLDVESAHRLLDVESAQRFFYSQGAQARRATLLLPPTLMAASSEDD-IDRRPIRRVRSKS-------DTPYLAEARISFNLG-------------------------------------------------------AAEEVERLAAMRSDSLVPGTHTPPIRRRSKFANLGRIFKPWKWR-KKKSEKFKHTSAALERKISMRQSREELIKRGVLKEIYDKDGELS----------------ISNEDDSLTNGQS-------LSSSQLSLPALSEMEPVPMPRDPCSYEVLQASDIMDGPDPGAPVKLP--------------------------------------------------------------------CLP---------------VKLSPPLPP----------------KKVLICMPVGGPELSLASYAAQKSSQQAVAQHHHTVLPSQMQHQLQYGSHGQHLPSSTGTLPMHPSG------------------------------------------------------------------------------------------------------------------------------------------------------------------CRMIDELNKTLAMTMQRLESSEQRVPCSTSYHSSGLHSSDGVTKAGPLG------------------------------------------------LPEIRQVPTVVIECDDNKENVPHEPDYEDS-----------------------------------------------SCLYAREEEEEEEDEDDDASLYTSSLAMKVCRKDSLAIKLSNRPSKRE--------------LEEKNILPRQTDEERLELRQQIGTKLTRRLSQRPTAEELEQR-------NILKPRNEQEEQEEKREIKRRLTRKLSQRPTVEELRERKILIRFSDYVEVADAQ---DYDRRADKP-WTRLTAADKAAIRKELNEFKSTEMEVHELSRHLTRFHRP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9C0D0-1", "uniprot_id": "PHAR1_HUMAN", "id": "Q9C0D0-1", "name": "Phosphatase and actin regulator 1", "aln": "-----------------------------------------------------------------------------------------------------------------------MDYP---KMDYFLDVESAHRLLDVESAQRFFYSQGAQARRATLLLPPTLMAASSEDD-IDRRPIRRVRSKS-------DTPYLAEARISFNLG-------------------------------------------------------AAEEVERLAAMRSDSLVPGTHTPPIRRRSKFANLGRIFKPWKWR-KKKSEKFKHTSAALERKISMRQSREELIKRGVLKEIYDKDGELS----------------ISNEEDSLENGQS-------LSSSQLSLPALSEMEPVPMPRDPCSYEVLQPSDIMDGPDPGAPVKLP--------------------------------------------------------------------CLP---------------VKLSPPLPP----------------KKVMICMPVGGPDLSLVSYTAQKSGQQGVAQHHHTVLPSQIQHQLQYGSHGQHLPSTTGSLPMHPSG------------------------------------------------------------------------------------------------------------------------------------------------------------------CRMIDELNKTLAMTMQRLESSEQRVPCSTSYHSSGLHSGDGVTKAGPMG------------------------------------------------LPEIRQVPTVVIECDDNKENVPHESDYEDS-----------------------------------------------SCLYTREEEEEEEDEDDDSSLYTSSLAMKVCRKDSLAIKLSNRPSKRE--------------LEEKNILPRQTDEERLELRQQIGTKLTRRLSQRPTAEELEQR-------NILKPRNEQEEQEEKREIKRRLTRKLSQRPTVEELRERKILIRFSDYVEVADAQ---DYDRRADKP-WTRLTAADKAAIRKELNEFKSTEMEVHELSRHLTRFHRP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58I1V4-1", "uniprot_id": "A0AC58I1V4_DANRE", "id": "A0AC58I1V4-1", "name": "Phosphatase and actin regulator", "aln": "----------------------------------------------------------------------------------------------------------------MHALIRSISAPSRGVTDRHGSAAAAPMAGPAFTGAHGTWITPRLTLREDASSSSSLSSSSSAEKPRKRRAFNLVKLRQPTAPGNNNTPFVISGHIKHICSNCSRGNDIR----------------------------------------------DAEGAERLAAMRSDSLVPGTHTPPIRRRSKLASLGRLFKPWKWR-KKKSDKFKQTSAVLERKMSMRQSREELIKRGVLKEVYEKADEVSGDSARVCVSDLERQTVLSPVSESAESSVTATVSFSEVQSSAEGLPCLSDLVPKPSQAPPPVKPLQSDSADISHVRPPSLKQPP--------------------------------------------------------------------ALPPKPYSRIPNHLTETLARLSPPLPP----------------KKVMICEPP--ATFPLKCLPSQGS------HVHTHTLTHTHSHSQQY---------ATLPLSLHPP-------------------------------------------------------------------------------------------------------------------------------------------------------------------SRIIEELNKTLALTMQRLESSVLQAVPSVLMETE----EEKENRESLHQ------------------------------------------------TPAVTHTHTLVTHT-----------------------------------------------------------------FSTREEEDEEEEEDDDESLFTSTLALRILRKDSLAIKLSNRPSKRE--------------LEDKNILPMMSDQERLESRQQIGTKLTRRLSQRPSAEELEQR-------NILKPRNEQEELEEKRELKKRLSRKLSQRPTVEELREAKILIRFSDYVEVAEAQ---DYDRRADKP-WTRLTAADKAAIRKELNEFKSSEMEVHESSRHLTRFHRP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZN0-1", "uniprot_id": "Q9VZN0_DROME", "id": "Q9VZN0-1", "name": "Phosphatase and actin regulator 4", "aln": "MSLRSNKLHSQQSTASSNSNGSNSSGNSGSNSNVQQQHPPMAYQQQQQQLLQQLQQQQKFQAQQRGNTSRNNLATLVAAINGHDGGQNSPGNSGYQLSPAAASRVAHAPPHSPLGPPSYSAATAQSAFSYYGQHQQHQMQLNHNYQQQQQQQFQLQQQQQQLQLPPPDLTDGIDHPSAQAATPPDSPNAQSTGPSDLEQQLCVVAKMQKSVTITVTPQRSNSMDFLNFEEKRQLIASSLSLSDILHSSNAQQQQQQAAKDGLAINGGQCAKKQNGAAIRTNSLGSGTRTPPLERKSKLSALGRFFKPWKWRRKKKSEKFEAASKSLERKISVRANRDELVQKGILMPESPLGNIPEPGEESYYNNSNSGATANGSLLNSAVHNNSMSQANN-SINATTGNPLISAAQQQLNQGLPNSISVQQFNGQNQNPQNSMANGLV--------------------------------------------------------------------GGGGGGGDGSSDTSSLSGGVPHSQSAP----------------QQLGVGQPPPPLTPLAQHHQALAQQLQQRFAISNNNEPRKDKTDAQQQQHGGNGTISTPNIEQPTCQGSMLPPPGGGGHHQVDGSGKMERPNTLAGANKLTRRGVNICYHNEHMYGEDGKMVGGPPGSTPPPYPGGKLPPGVMLSELPEPPIPLSEIGPIPPPPMFSTPSPTLIAGRPHGPGAVNDQDYQQDYDYDDNDPDQDELDSDDEYAPYGGNHVRMMDTQRVEEIPAKEPKPNAVPLKSALKKKGGMQPASASTPVTPTQEHGAGSAATAAAMANSNG------------------------------------------GIGSMAAAAAAAAQQSANQRPLVVRQDAAGNNYSLKPILRPRIRLCRQQMFNIQLPCTVENKENARPF---------VIRESSSDSDDSDGHIVYRDEDNDNTRLAKLARKESLSLKLQLRPDKQD--------------LINRNILHQVNDNELKESKEAIGARLIRRLSMRPTAEELVER-------NILKTQSPAEEKKQKEEKKSYLLRKLSFRPTVEELKE-KKIIRFNDYIEVTQAH---DYDRRADKP-WTRLTPKDKAAIRKELNEFKSSEMAVHEGSRHLTRFHRP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q501J7-1", "uniprot_id": "PHAR4_MOUSE", "id": "Q501J7-1", "name": "Phosphatase and actin regulator 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MEDPS--------------------------------------EEAEQP--------------------------------------------------------------------------------------SGDPGMGMDSVEAGDTTPPTKRKSKFSALGKIFKPWKWRKKKSSDKFKETSEVLERKISMRKPREELVKRGVLLEDPEQDGEDSGKLSHAALKNGHTTPIGSARSSSPVLVEE--EPE--RSLRNLTPEEESKKRLGSTGSQPNSE--AEPGPEHAPKQPLLPPKRPLSSS-----CEAKEVP-AGSTARSVSSTSGSTTVTSAATTAATDMTKTV-KSFVGPTPAPAPAPRTLPAAPASANTAAT----TTAPAKQPPIPP-------PKPAQRNS--NPIIAELSQAMNSGTVLSKPSPPLPPKRGIPSTSIPSLEPAASFTTKTANDQREK-TVSLCLEPPLIIPP-------------------------------------------------------------------------------------------------------------------------------SSPSPPLPTHIPPE-----PPR-SPLVPAKTFQIVPEVEFSSSSDLFQDIS--QQEDQKTEVPKKIQDQSFG-ESHIPSRLPPLP------------LHIRIQQALTSPLPVTPPLEG--THRAHSLLFENSDSFS-EDTGTLGRTRSLPITIEMLKVPDDEEEE-QTCP--FVEDVTSTSATPSLPLCLREEE-----KESDSDSEGPIKYRDEEED-DDDDESHQ-SALANRVKRKDTLAMKLSSRPSEPE---------------TNLNSWPRKSKEEWNEIRHQIGNTLIRRLSQRPTAEELEQR-------NILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKILR-FNEYVEVTDAH---DYDRRADKP-WTKLTPADKAAIRKELNEFKSSEMEVHVDSKHFTRYHRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AQY6-1", "uniprot_id": "A0A8I6AQY6_RAT", "id": "A0A8I6AQY6-1", "name": "Phosphatase and actin regulator 4", "aln": "---------------------------------------------------------------------------------------------------------------------MEAIPPLSTLAN------SGMEDPFDTAPPTPTCWLYSGMTPVSESTKRKALFWCHHSTRHMIEEAERP--------------------------------------------------------------------------------------SGDPGLVMDSVEAGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETSE---------------------------GGEDSGKLSHAALKNGHTTPIGSVRSSSPILSEE--EAE--GSLRNLTPEEDPKKRLGSTGSQPSSE--AEPGPEQASKQPLLPPKRPLSSSDEGNEGQAKEVP-AGSAARPVSSTSGSGIETPAATTAATDMTKTLTKSFVASTPAPTPAPRTLPAAPASTNTTAT----HPAPAKQPPIPP-------PKPAQRNS--NPIIAELSQAMNSGTLLSKPSPPLPPKRGIPSTSVSSSEPAASATAKTANDQREK-TVSLCLEPPLTIPP-------------------------------------------------------------------------------------------------------------------------------SSPSPPLPTHIPPE-----PPR-SPLVPAKTFQMVPEVEFSPSLDRFQDIS--QQEDQKKEVPKKIQDQSFG-ESHIPSRLPPVP------------LHIRIQQALTSPLPVTPPLEG--THRAHSLLFESSDSFS-EDTGTLGRTRSLPITIEMLKVPDDDEEE-QICP--FVEDMTSTSATPKLPPCLQEEE-----KESDSDSEGPIQYRDEEED-DDDDESYQ-SALANRVKRKDTLAMKLSSRPSEPE---------------TSLSSWPCKSKEEWNEIRHQIGNTLIRRLSQRPTAEELEQR-------NILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKILR-FNEYVEVTDAQ---DYDRRADKP-WTKLTPADKAAIRKELNEFKSSEMEVHVDSKHFTRYHRP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IZ21-1", "uniprot_id": "PHAR4_HUMAN", "id": "Q8IZ21-1", "name": "Phosphatase and actin regulator 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MEDPF--------------------------------------EEADQP--------------------------------------------------------------------------------------TTEPGMVLDSVEAGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETSEVLERKISMRKPREELVKRGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQVEE--EPVRLASLRKAIPEEDLKKRLGSTGSQPNSE--AESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTS--ITTAPAATTAATSLAKTVNLSVT-----PSPAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPP-------PKPAHRNS--NPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESAAAITTKTPSDEREKSTCSMGSELLPMISP-------------------------------------------------------------------------------------------------------------------------------RSPSPPLPTHIPPE-----PPR-TPPFPAKTFQVVPEIEFPPSLDLHQEIP--QQEDQKKEVPKRILDQNFG-EPHIPSRLPPLP------------LHIRIQQALTSPLPMTPILEG--SHRAHSLLFENSDSFS-EDSSTLGRTRSLPITIEMLKVPDDEEEEEQTCPSTFSEEMTPTSVIPKLPQCLREEEE----KESDSDSEGPIQYRDEE----DEDESYQ-SALANKVKRKDTLAMKLNHRPSEPE---------------LNLNSWPCKSKEEWNEIRHQIGNTLIRRLSQRPTPEELEQR-------NILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKILR-FNEYVEVTDAQ---DYDRRADKP-WTKLTPADKAAIRKELNEFKSSEMEVHEESKHFTRYHRP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PEI3-1", "uniprot_id": "PHR4B_DANRE", "id": "Q6PEI3-1", "name": "Phosphatase and actin regulator 4B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MENRD--------------------------------------DEVEHQ--------------------------------------------------------------------------------------HST--MGSEGGTAGDGTPPPKRKGKFSTLGKIFKPWKWRKKKSSEKFKETSEVLERKMSMRRPRQELIEQGVLKELPDNESGEAHGHKAPYVKNGHTLPVGVGGSLALEQVHSPSESEFRINPVWLPQPEDRRARAPSDGDHRGALGPRASNQDDGRRGGWSVGTEDWKNNLAWHGEDIRRGGRAHAEMDKRPGLMKAPSEDGRRTRPEPDWKPTLPRHSSVEEGRGRRESDSSQYLPNSEMMRDTLR--EPLPPKQSIMPPKWLMTSTPEPGSDSLPRTPVHNPAAPSFCS-SNSSSSSSAGKPLRNVSSAGANTAPPGGAPLTTSSAPCSMGTIPNHPSKQPPMPPPKPI---------------------------------------------------------------------------------------------------------------------------NRSNNPAIMAELTQGGMNLVPAKPSPPMPPKRTTPVTKRNPEDSPLTIASLPSILSEDMRANIPGGYQLPPPPPSPPLPTHIPPSPPR-------AHTHHLLHQHSYPYPLPQPLPVHFDPPSPPEDPPARDEDDYSDEEEEEEDDEDDEEPPPDHLPSPQSQPELEPRSRRCLVGELS-VSVIPEGNNSSEEEEDEEDQHPEESDSDGPVLYKDDESDEDEEDDSPP-SALASRVKRKDTLALKLSSRPSAPDRQAP------ERQAKSEHSGLSWQSKEQWEAIRTQIGTALTRRLSQRPTAEELEQR-------NILQPKNEADRQAEVREIKRRLTRKLSQRPTVAELQARKILR-FHEYVEVTSAQ---DYDRRADKP-WTKLTPADKAAIRKELNEFKSSEMEVHEESRIYTRFHRP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B1AVP0-1", "uniprot_id": "B1AVP0_MOUSE", "id": "B1AVP0-1", "name": "Phosphatase and actin regulator", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDKAVDGL--------------------------------------------------------------------------------------DKASIANSDGPPAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKISTRQSREELIRRGLLKELPDQDGDVTVNFE---NSNGHMIHIGEEATQEENVGKP--EEGSDSVCEKTPPREEQAEEKTENTEIHSEPTAAPTLPPTAPPKPKPKPK-------------------PKKSPGPPKGATAAASHKGDEVPPNRKNVKAPSKQAPTPPPKPTSRNTSREAAGSSHPKKAT--------GSKASASP-------STSSTSSRPRAPKESLAGKAGLVGTTRGKKKISKQP--VASRLSPSTTTSDTPSLKGEL---SDTGIESLTPEETVAGAEE------------------------------------------------------------------------------------------------------------------------------QATSKSK-AAIAL-----------PPSTAPPSPPALLLPPEDQCTIALDTP-MVLVSDGPTLPVSALDTSQLLWTEEPS-------------------------SRTS------------PYSSTGLGGSREQAKCFTTKDELG---PQLLTPGQMGDSSE-------------------SFSAPEDEAPREYQ------ANDSDSDGPILYTDDDDEEDDDDDSSGESALASKIRRRDTLAIKLGNRPSKKE--------------LEDKNILQRTSEEERQELRQQIGTKLVRRLSQRPTTEELEQR-------NILKQKNEEEEQEAKMELKRRLSRKLSLRPTVAELQARRILR-FNEYVEVTDSP---DYDRRADKP-WARLTPADKAAIRKELNEFKSTEMEVHEESRQFTRFHRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62025-1", "uniprot_id": "PHAR2_RAT", "id": "P62025-1", "name": "Phosphatase and actin regulator 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MGQTSVSALSPQPGSVDGL--------------------------------------------------------------------------------------DKASIANSDGPPAGSQTPPFKRKGKLSTIGKIFKPWKWRKEKTSDKFRETSAVLERKISTRQSREELIRRGLLKELPDQDGDVTVNFE---NSNGHMIHIGEEATQEENVGKP--EEGNVSVCEKGPPREEQAEEKT---------------------------------------------------------------------------------------------------AGSSHPKKTT--------GSKASSSP-------SASSTSSHPRGPKESLTGKAGAVGTTRGKKKISKQPAAAASRLSPNTVTSETSSLKGEL---SDTGVESLKPEETVAGAEE------------------------------------------------------------------------------------------------------------------------------EATGKPKAVVVAL-----------PPVTVPPSSPALPLPPEDPCTIALDTP-MVLVSDGPTLPISALETSPLPGTEEPA-------------------------NRTT------------PYSSTGLGGSREQAKCFTTKDGLGKAGPQLLTPGQMGDSLE-------------------SFSAPEDEAPREYQ------ANDSDSDGPILYTDDDDEEDDDDDSTGESALASKIRRRDTLAIKLGNRPSKKE--------------LEDKNILQRTSEEERQELRQQIGTKLVRRLSQRPTTEELEQR-------SILKQKNEEEEQEAKMELKRRLSRKLSLRPTVPELQARRILR-FNEYVEVTDSP---DYDRRADKP-WARLTPADKAAIRKELNEFKSTEMEVHEESRQFTRFHRP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75167-1", "uniprot_id": "PHAR2_HUMAN", "id": "O75167-1", "name": "Phosphatase and actin regulator 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDNAVDGL--------------------------------------------------------------------------------------DKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKISTRQSREELIRRGVLKELPDQDGDVTVNFE---NSNGHMIPIGEESTREENVVKS--EEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPK-------------------PKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTT--------GSKASASP-------STSSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQP--ITSHLSSDTTTSGTSDLKGEP---AETRVESFKLEQTVPGAEE------------------------------------------------------------------------------------------------------------------------------QNTGKFK-SMVPP-----------PPVAPAPSPLAPPLPLEDQCITASDTP-VVLVSVGADLPVSALDPSQLLWAEEPT-------------------------NRTT------------LYSGTGLSVNRENAKCFTTKEELGKTVPQLLTPGLMGESSE-------------------SFSASEDEGHREYQ------ANDSDSDGPILYTDDEDE-DEDEDGSGESALASKIRRRDTLAIKLGNRPSKKE--------------LEDKNILQRTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQR-------NILKQKNEEEEQEAKMELKRRLSRKLSLRPTVAELQARRILR-FNEYVEVTDSP---DYDRRADKP-WARLTPADKAAIRKELNEFKSTEMEVHEESRQFTRFHRP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T3V4-1", "uniprot_id": "A0AB32T3V4_DANRE", "id": "A0AB32T3V4-1", "name": "Phosphatase and actin regulator", "aln": "-----------------------------------------------------------------------------------------------------------MAEADSFSYLKTFPQVFPVFRVRSLSDTS-------------------------------AFRSRILTRLRSACSVEGL--------------------------------------------------------------------------------------EKSSLANCDVVGS-SQSPQLKGKGKLSSLGKIFKPWKWRKKRTSDKFQDLSKVLERKISTRQTREELIKKGVL--IPDQDD--PLNTE---TLNGHAVPSGGTEKVKVDIETP--EPVPEEKSDLAAVAEEPEERNDSKHIPQASESAALKPPAKKPPTTLPKPS-------------------AEATSTGVK---------------------------------------KGGQAGAKKVTKAT--------NKQVSAPP-------PKQTSRTATRGNAKTSNAKK-TTGTSKGSSQASGQS---SSQTSSKTSKNSNSEHTGQAK--TGKKTEPSRSQRPLSKTQE------------------------------------------------------------------------------------------------------------------------------TVESSSK-KDQKK-----------KELTTSVNEKAEEKSQNGKGDSHLSKC-AETDKRQSHVNQATEETSFIGSSNELS-------------------------SDAS------------AEP-VNVETETQKEKADQTQRDAGKEEGERQQT-VNVESAE-------------------VTIIP--DSIRENQ------ANDSDSDGPILYKDDDEEEDEDDEYTS-SSLASKIRRRDTLAIKLGNRPSKRE--------------LEEKNILPRTSEMERQELRQQIGCKLVRRLSQRPTTEELEQR-------NILKQKNEEEEHEAKQEIKRRLSRKLSVRPTVAELVARRILR-FNEYVEVTEAK---DYDRRADKP-WTRLTPADKAAIRKELNEFKSKEMEVHEESKQFTRFHRP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53858-1", "uniprot_id": "BNI4_YEAST", "id": "P53858-1", "name": "Protein BNI4", "aln": "------------------------------------------------------------------------------------------------------MSDSISDSKSSELLNSTFYSSTSINTLDHARTFRNSLILKEISDQSLNSSIKPCESVLDRDVESSVLQRSFGESNARDSEVQTVN-----------------------------------------------------------------------------------MTTSPSLSALADILNERSKYADQKTRKAQNIESSIIEEEEEAEEQNNSINYHEDITGSRLSVREEANENLAMTSPNLIDIDGSNSIQVAPLSLPSFEEPDFLSTPRVKPDSQGPRSKVSTRRTILERDNNLPVKREENTIINSETESTTHSAPFLKEDPKPSPPSSKLYNPKVRLNKAEARKYTDSSAQRTTSAGSVLEDTSMHKKKKSIFSFLKKKEPKPVIGNNSVTNEKNKMSSSSTFSMNIQTSLKTPEKLKKKSHSSSS-----IFNSFLKGKIETSDSPRKEPMRQKKRTPKSKDKKQDTEQIIDAASVLSTESPLLRKNHDDTPVKIDHVTRSIDQRKPTPLNMDLILGGDKQINTPLQEHVREDDDAKN-----------------------------------------------------------------------------------DLQLPTKDNFLSLDYEAPSPAFSKHDTGEVLFPKFLDNHEVDSIVSLERTRSTKSNKRSSMNSQRRSLTDTLSIKAQSEGMFITEASSVVLSTPDLTKSPASSILKNGRFEYSDNFSREHSYEGTTNEDFLDIKDDSGPLKKDDIFLESIEQKFDQLVMASDEEKTEVERDVPKPREEPLKKDSERQSVFADDDNELISDIMEFASFINFGDDDLN--LDLDLGDTTASYATETPEPVGNDEVNRSGTFDTRNNKEDSYKERETQSYSAAGATTYGDERQGQLHTFEQDGSEINDNEFENEDFNKHIEQPIEVTPRNNAYLPEFEPNRPVSMSFKGLKAPRMNTSFIDSMTPDSPVKSDLTSLGEVYVNSNNDQGVRFSSQIILYDTYGEFEYDRHPEISTCNQLTPQLAQMIKLELNELKS-AMEVHDDSRCYTHFY--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * : : : . :. .:.:. . .: : :.: : . . . .. : . * : .. *: . . *: . : .*. * * . : : : :***:.: . :*:. *: **** ** * ** *: *::: ", "identical_positions": 23, "similar_positions": 56, "identity": "1.97%" }, { "cls_id": "homologset.agr.SGD:S000005180", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2K5-1", "uniprot_id": "A0A0G2K2K5_RAT", "id": "A0A0G2K2K5-1", "name": "Mediator of RNA polymerase II transcription subunit 16", "aln": "----------------------------MMDLAYVCEWEKWAKSTYCPSLPLACAWSCRNLIAFTTDLRNDDQD--------------------LTHMIHILDTEHPWEVHSVSSGHSEAITCLEWDQSGSRLLSADADGQIKCWSMADHLANSWESSVGSQVE----------------------GDPIVALSWLHNGVKLALHVEKSGASSFGEKFSRVKFS-PSLTLFGGKPMEGWIAVTVSGLVTVSLLKPSGQ---------------VLTSTESLCRLRGRVALADIAFTGGGNIVVAAADGSSASPVKFYKVCVSVVSEKCRIDTEILPSLFMRCTTDPNRK-----DRFPAITHLKFLARDMSE-------QVLLCASSQTSSLVECWSLRKEGLPVNNIFQQISPVVGDKQPMILKWRILSATNDLDRVSAVALPKLPISLTNTDLKVASDTQFYPGLGLALAFQDGSVHMVHRLSLQTMAVFYS---SAPRSLDEPALKRPRTTGPAVHFKAMQLSWTSLALVGIDNHGKLSMLRISPSLGHALEPKLALQHLLFLLEYCMVTGYDWWDILLHVQPGMVQSLVERLHEEYTRQKPALQQVLSTRILAMKASLCKLSPCTMAR--------VCDYHTKLFLMAITSTLKSLLRPHFLNTPDKSPGDRLAEICAKITDVDIDKVMINLKTEEFVLDMNTLQALQQLLQWVGDFVLYLLVSLPNQGSA-----LRPGHSFLRDGAS----LGMLRELMVVIRIWGLLKPSCLPVYTATS-----------DTQDSMSLLFRLLTKLWICCRDEGPASEPDEGLVDECCLLPSQLLVPSLDWLPASDGLVSRLQPKQPLRLRFGRAPTLPSSTSILQLDGLTRAPGQPKIDHLRRLHLG-----------------------AYPTEECKACTRCGCVTMLKS--------PNKTTAVKQWEQRWIKNCLCGG----------------------------LWRRVPLSCS--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PGF3-1", "uniprot_id": "MED16_MOUSE", "id": "Q6PGF3-1", "name": "Mediator of RNA polymerase II transcription subunit 16", "aln": "-----------------------------MDLAYVCEWEKWAKSTYCPSLPLACAWSCRNLIAFTTDLRNDDQD--------------------LTHMIHILDTEHPWEVHSVSSGHSEAITCLEWDQSGSRLLSADADGQIKCWSMADHLANSWESSVGSQVE----------------------GDPIVALSWLHNGVKLALHVEKSGASSFGEKFSRVKFS-PSLTLFGGKPMEGWIAVTVSGLVTVSLLKPSGQ---------------VLTSTESLCRLRGRVALADIAFTGGGNIVVAAADGSSASPVKFYKVCVSVVSEKCRIDTEILPSLFMRCTTDPNRK-----DRFPAITHLKFLARDMSE-------QVLLCASSQTSSLVECWSLRKEGLPVNNIFQQISPVVGDKQPMILKWRILSATNDLDRVSAVALPKLPISLTNTDLKVASDTQFYPGLGLALAFQDGSVHMVHRLSLQTMAVFYS---SAPRSLDEPALKRPRTTCPAVHFKAMQLSWTSLALVGIDNHGKLSMLRISPSLGHPLEPKLALQHLLFLLEYCMVTGYDWWDILLHVQPGMVQSLVERLHEEYTRQKPALQQVLSTRILAMKASLCKLSPCTVAR--------VCDYHTKLFLMAITSTLKSLLRPHFLNTPDKSPGDRLAEICAKITDVDIDKVMINLKTEEFVLDMNTLQALQQLLQWVGDFVLYLLVSLPNQGSP-----LRPGHSFLRDGTS----LGMLRELMVVIRIWGLLKPSCLPVYTATS-----------DTQDSMSLLFRLLTKLWICCRDEGAASEPDEGLVDECCLLPSQLLVPNLDWLPASDGLVSRLQPKQPLRLRFGRAPTLPSSTSTLQLDGLTRAPGQPKIDHLRRLHLG-----------------------AYPTEECKACTRCGCVTMLKS--------PNKTTAVTQWEQRWIKNCLCGG----------------------------LWRRVPLSCS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2X0-1", "uniprot_id": "MED16_HUMAN", "id": "Q9Y2X0-1", "name": "Mediator of RNA polymerase II transcription subunit 16", "aln": "-----------------MCDLRRPAAGGMMDLAYVCEWEKWSKSTHCPSVPLACAWSCRNLIAFTMDLRSDDQD--------------------LTRMIHILDTEHPWDLHSIPSEHHEAITCLEWDQSGSRLLSADADGQIKCWSMADHLANSWESSVGSLVE----------------------GDPIVALSWLHNGVKLALHVEKSGASSFGEKFSRVKFS-PSLTLFGGKPMEGWIAVTVSGLVTVSLLKPSGQ---------------VLTSTESLCRLRGRVALADIAFTGGGNIVVATADGSSASPVQFYKVCVSVVSEKCRIDTEILPSLFMRCTTDLNRK-----DKFPAITHLKFLARDMSE-------QVLLCASSQTSSIVECWSLRKEGLPVNNIFQQISPVVGDKQPTILKWRILSATNDLDRVSAVALPKLPISLTNTDLKVASDTQFYPGLGLALAFHDGSVHIVHRLSLQTMAVFYSS--AAPRPVDEPAMKRPRTAGPAVHLKAMQLSWTSLALVGIDSHGKLSVLRLSPSMGHPLEVGLALRHLLFLLEYCMVTGYDWWDILLHVQPSMVQSLVEKLHEEYTRQTAALQQVLSTRILAMKASLCKLSPCTVTR--------VCDYHTKLFLIAISSTLKSLLRPHFLNTPDKSPGDRLTEICTKITDVDIDKVMINLKTEEFVLDMNTLQALQQLLQWVGDFVLYLLASLPNQGSL-----LRPGHSFLRDGTS----LGMLRELMVVIRIWGLLKPSCLPVYTATS-----------DTQDSMSLLFRLLTKLWICCRDEGPASEPDEALVDECCLLPSQLLIPSLDWLPASDGLVSRLQPKQPLRLQFGRAPTLPGSAATLQLDGLARAPGQPKIDHLRRLHLG-----------------------ACPTEECKACTRCGCVTMLKS--------PNRTTAVKQWEQRWIKNCLAVEGRGPDACVTSRASEEAPAFVQLGPQSTHHSPRTPRSLDHLHPEDRP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F602-1", "uniprot_id": "E7F602_DANRE", "id": "E7F602-1", "name": "Mediator of RNA polymerase II transcription subunit 16", "aln": "----------------------------MMDIAYVCEWEKRPKSNHCPSIPLVCAWSCRNLIAFTTDLKNEEDDKGLDNAFITNIT----TPVDLSHMIHIIDTDHPWDVYSINSGHNEIISCLEWDQSGSRLLSADGDGQIKCWGMTEHLVNSWECAQSSSVD----------------------GDPIVALSWLHNGVKLALHVEKSGSTNFGEKFSRVKFS-PSLTLFGGKPMEGWLAVTVSGLVTVSLLKPNGT---------------LLTASESLCRLRGRVALADIAFTGGGNIVVAATDGSSSSPVQFYKVCVSVVNEKCRIDTELLPSLFMRCTTDPLRR-----DKYPAVTHLKFLTRENSE-------QVLLCASSQMGSIVECWSLRKEGLPVNNIFQHRSPVVGEKQPMTLKWRILSTTNDLDRVSAVALPKLPISISNTDLKVASDTKFFPGLGLALAFHDGSIQILHRLSLQTVGMFYGSSGSSQRVGEEPAIKRQRAGGPMLHFKALQFSWTSLALVGIDNHGKLHMFRVSPSMGQMLDMNTLLRHLLFLLEYCMVTGYDWWDVLLHAQPGMVHNLLEKLHEEYMRQNQALQQVLSTRIVAVKASLCKLSSATAAR--------ACDFHAKLLLIAISSTLKSLLRPHVLNTPDKSPGDRLSEICAKNTDTDIDKVMINLKTEEFVLDGPPLQSLQQLIQWVGDFVLYLLANLPNQGSI-----VRPGFGFLRDGAS----LGMLREMLVMIRIWGLLKPGCLPIYTATS-----------DNQDSMFLLFRLLTKLWLCSRDESHPQDPDETLIDECCLLPSQLLVPSMDWLPINDGVITKIQGKHQLRLQFGKPYTLPGVNPNAQVE-IFRSPASQRVDHLRCLHLG-----------------------ISPTEDSKACTRCGCVTMLRS--------PNKTNATRQWEQRWIKNCLCGG----------------------------LWRRIPSTLS--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W278-1", "uniprot_id": "MED16_DROME", "id": "Q9W278-1", "name": "Mediator of RNA polymerase II transcription subunit 16", "aln": "-----------------------------MTILYKVEGKEFSKDSVFPHKKVLCSVSARNIVAFSALQSAIFPASHGGDAGDGSLPGAGLAVGASNSHVYVCDIVTPWEYYKVCSSK-SLISVLQWSPNGEQLLLGYVGGRVEIWQPRNQSINLWVLQYYATVP----------------------SEDIIEAQFFQNGKGVIFNALKKDHTYYAEKFERVEQQRPTLSGFGGVASEGCVLLTSSGLLAAFSLPAIQKTSAAGADGPAHEVVELTPALHSIGISRSFIEHCSMTPSPSGALNIAFSCGWQQQLVQCFKVSLSLEGELGLEQHLAIKSESQTSIFLGPLD-----GRRISHLKWTRIANEDVI-------FIAYACPDGAGSQLEQWTLTRRHQSVHALLQGGGGANNKPN-------EFVQSESWEQVGKVQLNASLADISVTRLSVSTP----DSCQVYAILQDNSVQVLE--------------PNSMKQLNHTQFDRLSDASGAVKFVSGDLTPSSQILLIFDSHAQLYAMQAPLPK--------QGGSGLLLLEYCIVTGCDASDVLLLNLG-NLEALVEKLTDNFTRQPSFVRHFYYANFLALKSNICRMQ--------------QQEFDNLIILHAISTTFKSLLRPSDLGFQDKGPADNLAIKLAESIP-DVDTVMLNLDAKDFTVEPVMLQSLQQLIQWVTDLALNMLHRLPEEVMKTKLSGKRPSYDISRDIVA----ISSLRELLVMIRIWGLLNTQCLPVYTKTM-----------DNIDVLVILFRLLTRLAQN------PAEPDEMLLDECSLLSKQLLIPQPTKFNPTT--LLSAQGFAAVKSGQLQFTSMEEPTCLQDMETEEVVFASSVKDGVSNLQLG-----------------------ARPS-HIRRCARCGFVFVNNASK------VAKTSALKAWFSKWLH-CHCGG----------------------------FWKQVH------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32259-1", "uniprot_id": "MED16_YEAST", "id": "P32259-1", "name": "Mediator of RNA polymerase II transcription subunit 16", "aln": "MMLGEHLMSWSKTGIIAYSDSQSSNANICLTFLESINGINWRFHTPQKYVLHPQLHEVQYQESSSTLSTHSTTTSVNGSTTAGVGSTPNFGGNSNKSPPQFFYNISSIHWNNWFSLPGDMLAVCDELGNMTMLITGQRPDRATTYEKLTMVFQDNVYKIYNHVMPLKPVDKLKPMNIERKQTRKEYNTSILEFRWLTSSKSVIVSQFCAFDSSSNTYRSRAQQVPPYGVYHPPFIKYACLAIRKNGQIDFWYQFSNSKD-------HKKITLQLLDTSNQRFKDLQWLEFARITPMNDDQCMLITTYSKLSKNISFYKLHVNWNLNATKPNVLNDPSLKIQFILSTTLDPTDDEGHVLKLENLHVVSKSSIEKDPSPEILVLYNVCDTSKSLVKRYRLAPTQLSAEYLVILKPDLNIDRNNSTNQIFQSRRYN-LRRHSDIVLDKKVTLITSEMFDAFVSFYFEDGTIESYNQNDWKLETERLISQSQLGKFKN---IIASPLSAGFNYGKLPLPPSVEWMKVSPSMCGVIVKQYNKKWPQFYAAVQKNYADPEKDSINATALAFGYVKSLHKQISAEDLTIAAKTHILRISFLDRKRAKEFITTLLKSLYSFFNISPDAPKEIMDKIITSRPLQKIMLLQLELGSCFSQENIEEMARVILYLKNVLFAFNGVARNFHFAIEQISNNSNQQQNPKLFQTIFSKQ-DLIHSLIPVAKWFVKFITYLTQEILILINDPTNKEYTLVHGIFGAKMSRTLILSILNEIKKVTQIVAKFPETSYPILNESSTFLKLVLSESPVDFEKFETFLVDVNNKFIALCEQQPSQEREFSLLVKAEIPPEYAKVGDFLLQYANNAVISHANAAAVYFADTSGLKISNSEFFNPEIFHLLQPLEEGLIIDTDKLPIKNRTSKSFSKLLYDDVTCDKLSVSEISDGKLKRCSRCGSVTRAGNIISSDKTIVPTSIQTKRWPTMYTRLCICSG----------------------------MLFEMDG-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . . : : : . . . . . * . :: : . *: . .: : : * . *: :: .. : . : .*.: * . . : : .* : . : : .. : . :: .. : : . . :. :*: :. : : * .: : ::.. : . * :: : * ... :. . : : : . : * :: :.. . :* .:. . . :. . : . : :.: : .: . . *: : :. . :: . :: .: :. : : * : :* : :. . .: : . : :* * : :::* : :*. .: : : ..: : :. *.*: : :* . : . *: . : : : :: :.. . : : *: :. : .. : . . : : :: . * : . . : *:*** * : * : : * . . ", "identical_positions": 33, "similar_positions": 204, "identity": "3.22%" }, { "cls_id": "homologset.agr.SGD:S000005182", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63415-1", "uniprot_id": "PCSK6_RAT", "id": "Q63415-1", "name": "Proprotein convertase subtilisin/kexin type 6", "aln": "-------------------------------------------------------------------------------------MPPRAPPAPGPRPPPR------------------AAGRHGLSPLAPRPWRWLLLLALPAVCSALPPP---------------------------------------------------------------------------------------------------------------------RPVYTNHWAVQVLGGPGA--ADRVAAAHGYLNLG-QIGNLDDYYHFYHSKTFKRSTLS---SRGPHTFLRMDPQVKWLQQQEVKRRVKR-QARSD-----------------------------------------------SLYFNDPIWSNMWYMHCADKNSR-CRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDG-DVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDHCSCDGYTNSIYTISVSSTTENGHKPWYLEECASTLATTYSSGAF-YERKIVTTDLR------QRCTDGHTGTSVSAPMVAGIIALALEANNQLTWRDVQHLLVKTSRPAHLKASD----WKVNGAGHKVSHLYGFGLVDAEALVLEA--RKWTAVPSQHMCVATA-DKRPRSIPVV--QVLRTTALTNACAD-HSDQRVVYLEHVVVRISISHPRRGDLQIHLISPSGTKSQLLAKRLLDFSN-EGFTNWEFMTVHCWGEKAEGEWTLEVQDIPSQVRNPEKQGKLKEWSLILYGTAEHP-------------------------------------------------------YRTFSSHQSRSRMLELSVPEQEPLKAEGPPPQAETPEEEEEYTG-------------VCHPECGDKGCDGPSADQCLNCVHFSLGNSKTNRKCVSECPLGYFGDTAARRCRRCHKGCETCTGRSPTQCLSCRRGFYHHQETNTCVTLCPAGLYADESQRLCLRC-HPSCQKCVDEPEKSTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCRTCVGPSREECIHCAKSFHFQDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCEG-SSRNCSRCKAGFTQLGTSCITN--HTCSN----ADETFCEMVKS------------------NRLCERKL-----FIQFC-----------------CRTCLLAG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F6XJP7-1", "uniprot_id": "F6XJP7_MOUSE", "id": "F6XJP7-1", "name": "Proprotein convertase subtilisin/kexin type 6", "aln": "-------------------------------------------------------------------------------------MPPRAPPAPGPRPPPRAADV---------ARGAGAAGRHGLPPLALRPWRWLLLLALPAACSALPPP---------------------------------------------------------------------------------------------------------------------RPVYTNHWAVQVLGGPGA--ADRVAAAHGYLNLG-QIGNLDDYYHFYHSKTFKRSTLS---SRGPHTFLRMDPQVKWLQQQEVKRRVKR-QARSD-----------------------------------------------SLYFNDPIWSNMWYMHCTDKNSR-CRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDG-DVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDHCSCDGYTNSIYTISVSSTTENGHKPWYLEECASTLATTYSSGAF-YERKIVTTDLR------QRCTDGHTGTSVSAPMVAGIIALALEANNQLTWRDVQHLLVKTSRPAHLKASD----WKVNGAGHKVSHLYGFGLVDAEALVLEA--RKWTAVPSQHVCVATA-DKRPRSIPIV--QVLRTTALTNACAD-HSDQRVVYLEHVVVRISISHPRRGDLQIHLISPSGTKSQLLAKRLLDFSN-EGFTNWEFMTVHCWGEKAEGEWTLEVQDIPSQVRNPEKQGKLKEWSLILYGTAEHP-------------------------------------------------------YRTFSSHQSRSRMLELSVPEQEPPKAAGQPPQAETPEDEEEYTAPSIQGSPNTLQTSVCHPECGDKGCDGPNADQCLNCVHFSLGNSKTNRKCVSECPLGYFGDAAARRCRRCHKGCETCTGRSPAQCLSCRRGFYHHQETNTCVTLCPAGLYADESQRLCLRC-HPSCQKCVDEPEKCTVCKEGFSLARGSCIPDCEPGTYFDSELVKCGECHHTCRTCVGPSREECIHCAKSFHFQDWKCVPACGEGFYPEEMPGLPHKVCRRCEENCLSCEG-SSRNCSRCKAGFTQLGTSCITN--HTCSN----ADETFCEMVKS------------------NRLCERKL-----FIQFC-----------------CRTCLLAG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29122-1", "uniprot_id": "PCSK6_HUMAN", "id": "P29122-1", "name": "Proprotein convertase subtilisin/kexin type 6", "aln": "-------------------------------------------------------------------------------------MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAACSAPPP----------------------------------------------------------------------------------------------------------------------RPVYTNHWAVQVLGGPAE--ADRVAAAHGYLNLG-QIGNLEDYYHFYHSKTFKRSTLS---SRGPHTFLRMDPQVKWLQQQEVKRRVKR-QVRSDP---------------------------------------------QALYFNDPIWSNMWYLHCGDKNSR-CRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDG-DVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAF-YERKIVTTDLR------QRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASD----WKVNGAGHKVSHFYGFGLVDAEALVVEA--KKWTAVPSQHMCVAAS-DKRPRSIPLV--QVLRTTALTSACAE-HSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSN-EGFTNWEFMTVHCWGEKAEGQWTLEIQDLPSQVRNPEKQGKLKEWSLILYGTAEHP-------------------------------------------------------YHTFSAHQSRSRMLELSAPELEPPKAALSPSQVEVPEDEEDYTAQSTPGSANILQTSVCHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCETCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKC-HPSCKKCVDEPEKCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFHFHDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCAG-SSRNCSRCKTGFTQLGTSCITN--HTCSN----ADETFCEMVKS------------------NRLCERKL-----FIQFC-----------------CRTCLLAG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04592-1", "uniprot_id": "PCSK5_MOUSE", "id": "Q04592-1", "name": "Proprotein convertase subtilisin/kexin type 5", "aln": "-----------------------------------------------------------------------------------------------------------------------MDWDWGNRCSRPGRRDLLCVLALLAGCLLPVCR---------------------------------------------------------------------------------------------------------------------TRVYTNHWAVKIAGGFAE--ADRIASKYGFINVG-QIGALKDYYHFYHSRTIKRSVLS---SRGTHSFISMEPKVEWIQQQVVKKRTKRDYDLSHA---------------------------------------------QSTYFNDPKWPSMWYMHCSDNTHP-CQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAATANNSHCTVGIAFNAKIGGVRMLDG-DVTDMVEAKSVSYNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGES-YDKKIITTDLR------QRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLNAND----WKTNAAGFKVSHLYGFGLMDAEAMVMEA--EKWTTVPQQHVCVEST-DRQIKTIRPN--SAVRSIYKASGCSD-NPNHHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSM-EGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQP-------------------------------------------------------YSPTNEFPKVERFRYSRVEDPTDDYG------------AEDYAG-------------PCDPECSEVGCDGPGPDHCSDCLHYYYKLKNNTRICVSSCPPGHYHADKKR-CRKCAPNCESCFGSHGNQCLSCKYGYFLNEETSSCVTQCPDGSYEDIKKNVCGKC-SENCKACIG-FHNCTECKGGLSLQGSRCSVTCEDGQFFNGHD--CQPCHRFCATCSGAGADGCINCTEGYVMEEGRCVQSCSVSYYLDHSSEGGYKSCKRCDNSCLTCNGPGFKNCSSCPSGYLLDLGTCQMG--AICKDGEYIDDQGHCQTCEASCAKCWGPTQEDCISCPVTRVLDDGR-----CVMNCPSWKFEFKKQCHPCHYTCQGCQGSGPSNCTSCRADKHGQERFLYHGECLENCPVGHYPAKGHACLPCPDNCELCYNPHVCSRCMSGYVIIPPNHTCQKLECRQGEFQDSEYEECMPCEEGCLGCTEDDPGACTSCATGYYMFERHCYKACPEKTF--GVKWECRACGTNCGSCDQHECYWCEEGFFLSGGSCVQDCGPGFHGDQELGECKPCHRACENCTGSGYNQCSSCQEGLQLWHGTCLWSTWPQVEGKDWNEAVPTEKPSLVRSLLQDRRKWKVQIKRDATSQNQPCHSSCKTCNG---SLCASCPTGMYLWLQACVPSCPQGTWPSVTSGSCEKCSEDCVSCSGADLCQQCLSQPDNTLLLHEGRCYHSCPEGFYAKDGVCEHCSSPCKTCEGNATSCNSCEGDFVLDHGVCWKTCPEKHVAVEGVCKHCPERCQDCIHEKTCKECMPDFFLYNDMCHRSCPKSFYPDMRQ--CVPCHKNCLECNGPKEDDCKVCADTSKALHNGLCLDECPEGTYKEEENDECRDCPESCLICS--SAWTCLACREGFTV-VHDVCTAPKECAAVEYWDEGSHRCQPCHKKCSRCSGPSEDQCYTCPRETFLLNTTCVKECPEGYHTDKDSQQCVLCHSSCRTCEGPHSMQCLSCRPGWFQLGKECLLQCRDGYYGESTSGRCEKCDKSCKSCRGPRPTDCQSCDTFFFLLRSKGQCHRACPEHYYADQHAQTCERCHPTCDKCSGKEAWSCLSCVWSYHLLKGICIPECIVGEYREGKGENFNCKKCHESCMECKGPGSKNCTGCSAGLLLDMDDNRCLHCCN----ASHSRRSQDCCDCQSSTDECILPAR-EAEFYEHT----KTALLVTSGAMLLLLLGAAAVVWRKSRS------RPVAKGRYEKLAE-------------PTVSYSSYRSSY-----LDEDQVIEYRDR-----DYDEDDED-DIVYMGQDGTVYRKFKYGLLDETEDDELEYDDESYSYQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41413-1", "uniprot_id": "PCSK5_RAT", "id": "P41413-1", "name": "Proprotein convertase subtilisin/kexin type 5", "aln": "-----------------------------------------------------------------------------------------------------------------------MDWGWGSRCCRPGRRDLLCVLALLAGCLLPVCR---------------------------------------------------------------------------------------------------------------------TRVYTNHWAVKIAGGFAE--ADRIASKYGFINVG-QIGALKDYYHFYHSRTIKRSVLS---SRGTHSFISMEPKVEWIQQQVVKKRTKRDYDLSRA---------------------------------------------QSTYFNDPKWPSMWYMHCSDNTHP-CQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAATANNSHCTVGIAFNAKIGGVRMLDG-DVTDMVEAKSVSYNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGES-YDKKIITTDLR------QRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLNAND----WKTNAAGFKVSHLYGFGLMDAEAMVMEA--EKWTTVPQQHVCVEST-DRQIKTIRPN--SAVRSIYKASGCSD-NPNHHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSM-EGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQP-------------------------------------------------------YSPTNEFPKVERFRYSRVEDPTDDYG------------AEDYAG-------------PCDPECSEVGCDGPGPDHCTDCLHYHYKLKNNTRICVSSCPPGHFHADKKR-CRKCAPNCESCFGSHADQCLSCKYGYFLNEETSSCVAQCPEGSYQDIKKNICGKC-SENCKTCTG-FHNCTECKGGLSLQGSRCSVTCEDGQFFSGHD--CQPCHRFCATCAGAGADGCINCTEGYVMEEGRCVQSCSVSYYLDHSLEGGYKSCKRCDNSCLTCNGPGFKNCSSCPSGYLLDLGMCQMG--AICKDGEYIDEQGHCQICDASCAKCWGPTQDDCISCPITRVFDDGR-----CVMNCPSWKFELKKQCHPCHHTCQGCQGSGPSNCTSCKA---------------------------------------------------------------------GEFQDSEYGECMPCEEGCVGCTVDDPGACTSCATGYYMFERHCYKACPEKTF--GEKWECKACGTNCGSCDQHECYWCEEGFFLSSGSCVQDCDPGFYGDQELGECKPCHRACETCTGLGYNQCSSCPEGLQLWHGTCIWPTWPHVEGKVWNEAVPTEKPSLVRSLPQDRRKWKVQIKRDATRQYQPCHSSCKTCNG---SLCTSCPAGTYLWLQACVPSCPQGTWLSVRSSSCEKCAEGCASCSGDDLCQRCLSQPSNTLLLHEGRCYHSCPEGFYAKDGVCEHCSSPCKTCKGNATSCHSCEGDFVLDHGVCWETCPEKHVAVEGVCKHCPERCQDCIHEKTCKECMPDFFLYNDMCHHSCPKNFYPDMRQ--CVPCHKNCLGCNGPKEDDCKACADTSKVLHNGLCLDECPKGTYKDEVNDECRDCPESCLICS--SAWTCLTCREGFTV-VQDVCTAPKECAAIEYWDVGSHRCQPCHRKCSRCSGPSENQCYTCPRETFLLNTTCVKECPEGYHTDKDSHQCVPCHSSCRTCEGPHSMQCLSCRPGWFQLGKECLLQCRDGYYGESTSGRCEKCDKSCKTCRGPQPTDCQSCDTFFFLLRSKGQCHLACPEHYYADQHAQTCERCHPTCDKCSGKEAWNCLSCVWSYHLLKGICTPECIVGEYRDGKGENFNCKKCHESCMECKGPGSKNCTGCSAGLLLQMDDSRCLRCCN----ASHPHRSQDCCDCQSSTDECILPASDDTVFHEHT----KTALLVTSGAMLLLLLGAAVVVWRKSRS------QPVAKGRYEKLAE-------------PTVSYSSYRSSY-----LDEDQVIEYRDR-----DYDEDDED-DIVYMGQDGTVYRKFKYGLLDEAEDDELEYDDESYSYQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92824-1", "uniprot_id": "PCSK5_HUMAN", "id": "Q92824-1", "name": "Proprotein convertase subtilisin/kexin type 5", "aln": "-------------------------------------------------------------------------------------------------------------------------MGWGSRCCCPGRLDLLCVLALLGGCLLPVCR---------------------------------------------------------------------------------------------------------------------TRVYTNHWAVKIAGGFPE--ANRIASKYGFINIG-QIGALKDYYHFYHSRTIKRSVIS---SRGTHSFISMEPKVEWIQQQVVKKRTKRDYDFSRA---------------------------------------------QSTYFNDPKWPSMWYMHCSDNTHP-CQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAAAANNSHCTVGIAFNAKIGGVRMLDG-DVTDMVEAKSVSFNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGES-YDKKIITTDLR------QRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLNAND----WKTNAAGFKVSHLYGFGLMDAEAMVMEA--EKWTTVPRQHVCVEST-DRQIKTIRPN--SAVRSIYKASGCSD-NPNRHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSM-EGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQP-------------------------------------------------------YSPTNEFPKVERFRYSRVEDPTDDYG------------TEDYAG-------------PCDPECSEVGCDGPGPDHCNDCLHYYYKLKNNTRICVSSCPPGHYHADKKR-CRKCAPNCESCFGSHGDQCMSCKYGYFLNEETNSCVTHCPDGSYQDTKKNLCRKC-SENCKTCTE-FHNCTECRDGLSLQGSRCSVSCEDGRYFNGQD--CQPCHRFCATCAGAGADGCINCTEGYFMEDGRCVQSCSISYYFDHSSENGYKSCKKCDISCLTCNGPGFKNCTSCPSGYLLDLGMCQMG--AICKDGEYVDEHGHCQTCEASCAKCQGPTQEDCTTCPMTRIFDDGR-----CVSNCPSWKFEFENQCHPCHHTCQRCQGSGPTHCTSCGADNYGREHFLYQGECGDSCPEGHYATEGNTCLPCPDNCELCHSVHVCTRCMKGYFIAPTNHTCQKLECGQGEVQDPDYEECVPCEEGCLGCSLDDPGTCTSCAMGYYRFDHHCYKTCPEKTY--SEEVECKACDSNCGSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWN---------------------------DILRKLQPCHSSCKTCNGSA-TLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGVCQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADSRH--CVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHKSCLTCS--SSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCPANLVLHMDDSHCLHCCN----TSDPPSAQECCDCQDTTDECILRTSKVRPATEHF----KTALFITSSMMLVLLLGAAVVVWKKSRGR----VQPAAKAGYEKLAD-------------PNKSYSSYKSSYRESTSFEEDQVIEYRDR-----DYDEDDDD-DIVYMGQDGTVYRKFKYGLLDDDDIDELEYDDESYSYYQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q4U3-1", "uniprot_id": "A0A8M9Q4U3_DANRE", "id": "A0A8M9Q4U3-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------MTSTIFFPYALFFGIGLQCVQ---------------------------------------------------------------------------------------------------------------------MRLYTNRWAVKITGGPEA--ADLIAEKYGFVNMG-QIGGLVDHYQFQHSGIIKRSTIK---SKGNHSLITMETKVEWIQQQMVQKRVKRTETMDQT---------------------------------------------HDGSFNDPKWDSMWYIHCDHN----CLTDMNIQAAWRRGYTGKGVVVSILDDGIERQHPDLKQNYDARASYDVNGNDPDPTPRYDVTNENKHGTRCAGVVAASANNSLCIVGIAYNAKIGGVRMLDG-DMTDMVEAQSLNLRQQYIDIYSSSWGPDDDGRTVDGPGPLARLALENGIRKGRKGRGSIFVWASGNGGQSQDHCSCDGYTNSIYTISVGSTTQSGRKPWYLEECSSTLATTYSSGDS-HSPGVVTTDLR------QRCTDEHSGTSASAPMAAGIIALTLEANPALTWRDIQHIIVKTSSRGHLSASD----WQSNGAGYDVSHLYGFGLLNAEAMVKNA--ETWKQVPSQHICEENI-GQNARIISPE--RVLRSVLKSSGCSA-QRLQRVVYLEHVIVRVTITHPHRGDLSITLTSPSGTTSQLLANRPNDHSS-EGFIKWEFMTTHCWGERLAGDWILDIRDTPSPQRNNRLQGKLVEWSLVLYGTSTHP-------------------------------------------------------YIR-HEQPRSAQL-------PSEDEI------------TEEYNG-------------SCDPECSEDGCEGPGPHQCVSCLNLFLKFKNNTRTCVSECPSG-YWGDKKR-CKKCYSSCKSCLGSRSDQCTACKSGYHLNEEKNNCVTSCEDGYFLYHEENLCRKCNIENCMKCTS-ASICTECSEGTSLVGNRCQKSCEVGSYYSEPEDSCEACHPACATCAAAGLESCNRCAEGYLMENWRCVSSCSQGFYAEQQNSDNQSTCKRCDASCLACVGPTKTNCSECVDGHSLQDGVCVLS--HNCGDGEYQDESGECQSCHVSCQKCKGPQSEDCLSCFITHLLDYGQ-----CVVSCSNGKYPSGGQCHLCDHTCAQCVDAGPSNCTSCDTDKFGVDRYLYHGECVDACPKAHFHTVLKACEPCPSYCKLCSSATHCIKCEDSFYVN--NGVCNKLECGEGEVEDPEYDDCMPCEEGCHKCVLYNPKHCLSCINGYYRFEESCYKNCPSKTYPVEETMSCVSCEHDCVNCDEDECSWCEADFFISNGKCVRECPDGFYNDDESQECEECHSDCKTCSGPEDSDCESCSEGLTLDNGACVSEQDVCPAQMYLTD----------------------------DGECEACHPLCESCWGKMKNQCNTCVKGRYLNADQCVARCPVGSFGSKDSGHCETCPQGCAQCQDEQLCTRCQSTRKNPLYLQAGQCVRKCTRG-YPVGQVCKSCASACTSCEKNATHCMSCEGTLLLYKHECVSSCPSAHTVSNGECVQCQENCAICS-EDGCTGCKEDYFLHVGQCIAVCPDGFFEDMNQGICKRCHVDCSLCDGPESNNCDACSDSDSTLHYGACLTPCSSHTYRESRSGECIDCDSSCLTCSGPHDTSCTSCSEGLKMDAHGRCATPTTCPSHHYSNQDGE-CHLCHKYCHECSGPHQDQCLSCNQKHYLLNGSCVNNCPDEYFSG-ETQRCEPCHPNCLTCMGRHSHECLSCRDHLYRDVKECVDTCRSGYYASAVSSTCERCDESCGECLQAGAEGCVSCRQGMLFIRKQGRCVSSCPESYYHDTHHKTCEACHPSCRTCIGKSVEDCDTCYPGFTLTGGVCESPCITGEYAKSEEQDYNCESCDESCLECKGPGPHNCTICPAQFILASE-GRCLPCCTNTELEDAATVQQECCNCTENRGECVLSTNFAFRNHEEEDYTGNLPLFITTSILLVFVLIAVIMLIKRSLSKRALPDTPVPRG-YEKLGHDGGRDSFYRGTSSATSAYSGQASSS--SGHFRESKLVDLGDQKGSRDDDDEDDEDEDIVYMGQDGTVYRKFKYGQLGDEQEDELEYDDESYNYR-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P29121-1", "uniprot_id": "PCSK4_MOUSE", "id": "P29121-1", "name": "Proprotein convertase subtilisin/kexin type 4", "aln": "---------------------------------------------------------------------------------------------------------------------------MRPSQTELWLGLTLTLALL---AVRWASA--------------------------------------------------------------------------------------------------------------------QAPIYVSSWAVRVTKGYQE--AERLARKFGFVNLG-QIFPDDQYFHLRHRGVAQQSLTP---HWGHRLRLKKDPKVRWFEQQTLRRRVKRSL----------------------------------------------------VVPTDPWFSKQWYMNKEIQQ------DLNILKAWNQGLTGRGVVISILDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPNDENRHGTRCAGEVSATANNGFCGAGVAFNARIGGVRMLDG-AITDIVEAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGLLTQEAFRRGVTKGRQGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTRQGRVPWYSEACASTFTTTFSSGVV-TDPQIVTTDLH------HQCTDKHTGTSASAPLAAGMIALALEANPLLTWRDLQHLVVRASRPAQLQAED----WRINGVGRQVSHHYGYGLLDAGLLVDLA--RVWLPTKPQKKCAIRV-VHTPTPIL----PRMLVPKNVTACSDGSRRRLIRSLEHVQVQLSLSYSRRGDLEIFLTSPMGTRSTLVAIRPLDISG-QGYNNWIFMSTHYWDEDPQGLWTLGLENKG----YYFNTGTLYYYTLLLYGT-------------------------------------------------------------------------------------------------AEDMTARPQAPQVTS-----------------------------------------------------------------------------------------------------------------------------------------------------------------RARACVQRDTEGLCQESHSPLSILAGLCLISSQQWWWLYS------------HPQQPVTE---------------------------------------GQASCHP--------------PVTPAAAA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q78EH2-1", "uniprot_id": "PCSK4_RAT", "id": "Q78EH2-1", "name": "Proprotein convertase subtilisin/kexin type 4", "aln": "---------------------------------------------------------------------------------------------------------------------------MRPSQTALWLGLVLSLALL---AVGWASA--------------------------------------------------------------------------------------------------------------------RPPIYVSSWAVRVTKGYQE--AERLARKFGFVNLG-QIFPDDQYFHLRHRGVAQQSLTP---HWGHRLRLKKEPKVRWFEQQTLRRRVKRSL----------------------------------------------------VVPTDPWFSKQWYMNKEIEQ------DLNILKVWNQGLTGRGVVVSILDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPNDENRHGTRCAGEVSATANNGFCGAGVAFNARIGGVRMLDG-AITDIVEAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGLLTQEAFRRGVTKGRQGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTRQGRVPWYSEACASTFTTTFSSGVV-TDPQIVTTDLH------HQCTDKHTGTSASAPLAAGMIALALEANPLLTWRDLQHLVVRASRPAQLQAED----WRINGVGRQVSHHYGYGLLDAGLLVDLA--RVWLPTKPQKKCTIRV-VHTPTPIL----PRMLVPKNVTVCCDGSRRRLIRSLEHVQVQLSLSYSRRGDLEIFLTSPMGTRSTLVAIRPLDISG-QGYNNWIFMSTHYWDEDPQGLWTLGLENKG----YYYNTGTLYYCTLLLYGT-------------------------------------------------------------------------------------------------AEDMTARPQTP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QESHCPLSIVAELCLISSKQWWWLYS------------HTQQPVTK---------------------------------------GQDSCHP--------------PTTPARQLDQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLHCLFPAPHAGSASEPLQG-------LSP-------------------------------LAAILAISLG-PWCCPC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UW60-1", "uniprot_id": "PCSK4_HUMAN", "id": "Q6UW60-1", "name": "Proprotein convertase subtilisin/kexin type 4", "aln": "---------------------------------------------------------------------------------------------------------------------------MRPAPIALWLRLVLALALVRPRAVGWAPV--------------------------------------------------------------------------------------------------------------------RAPIYVSSWAVQVSQGNRE--VERLARKFGFVNLG-PIFPDGQYFHLRHRGVVQQSLTP---HWGHRLHLKKNPKVQWFQQQTLQRRVKRSV----------------------------------------------------VVPTDPWFSKQWYMNSEAQP------DLSILQAWSQGLSGQGIVVSVLDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPSKENRHGTRCAGEVAAMANNGFCGVGVAFNARIGGVRMLDG-TITDVIEAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGILTREAFRRGVTKGRGGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTQQGRVPWYSEACASTLTTTYSSGVA-TDPQIVTTDLH------HGCTDQHTGTSASAPLAAGMIALALEANPFLTWRDMQHLVVRASKPAHLQAED----WRTNGVGRQVSHHYGYGLLDAGLLVDTA--RTWLPTQPQRKCAVRV-QSRPTPIL----PLIYIRENVSACAG--LHNSIRSLEHVQAQLTLSYSRRGDLEISLTSPMGTRSTLVAIRPLDVST-EGYNNWVFMSTHFWDENPQGVWTLGLENKG----YYFNTGTLYRYTLLLYGT-------------------------------------------------------------------------------------------------AEDMTARPTGPQVTS-----------------------------------------------------------------------------------------------------------------------------------------------------------------S--ACVQRDTEGLCQACDGPAYILGQLCLAYCPPRFFNHTR----LVTAGPGHTAAPALR---------------------------------------VCSSCHASCYTCRGGSPRDCTSCPPSSTLDQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QQGSCMGPTTPDSRPRLRAA-------ACPHHRCPASA----------------------MVLSLLAVTLGGPVLCGMSMDLPLYAWLSRAR----ATPTK------------------PQVWLPAGT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23188-1", "uniprot_id": "FURIN_MOUSE", "id": "P23188-1", "name": "Furin", "aln": "---------------------------------------------------------------------------------------------------------------------------MELRSWLLWVVAAAGAVVL----LAADAQ--------------------------------------------------------------------------------------------------------------------GQKIFTNTWAVHIPGGPAV--ADRVAQKHGFHNLG-QIFGD--YYHFWHRAVTKRSLSP---HRPRHSRLQREPQVKWLEQQVAKRRAKRDVY---------------------------------------------------QEPTDPKFPQQWYLSGVTQR------DLNVKEAWAQGFTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDG-EVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ-NEKQIVTTDLR------QKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNADD----WATNGVGRKVSHSYGYGLLDAGAMVALA--QNWTTVAPQRKCIVEI-LVEPKDIG----KRLEVRKAVTACLG--EPNHITRLEHVQARLTLSYNRRGDLAIHLISPMGTRSTLLAARPHDYSA-DGFNDWAFMTTHSWDEDPAGEWVLEIENTS----EANNYGTLTKFTLVLYGT-------------------------------------------------------------------------------------------------APEGLSTPPESS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------GCKTLTSSQACVVCEEGYSLHQKSCVQHCPPGFIPQVL----DTHYSTENDVEIIRAS--------------------------------------VCTPCHASCATCQGPAPTDCLSCPSHASLDP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VEQTCSRQSQSSRESRPQQQPPALRPEVEMEPRLQAG-----------------------LASHLPEVLAGLSCLIIVLIFGIVFLFLHRCS----GFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEGRGERTAFIKDQSAL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23377-1", "uniprot_id": "FURIN_RAT", "id": "P23377-1", "name": "Furin", "aln": "---------------------------------------------------------------------------------------------------------------------------MELRPWLLWVVAAAGALVL----LAAEAR--------------------------------------------------------------------------------------------------------------------GQKIFTNTWAVHISGGPAV--ADSVARKHGFHNLG-QIFGD--YYHFWHRAVTKRSLSP---HRPRHSRLQRVPQVKWLEQQVAKQRAKRDVY---------------------------------------------------QEPTDPKFPQQWYLSGVTQR------DLNVKEAWAQGFTGRGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDG-EVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ-NEKQIVTTDLR------QKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNAND----WATNGVGRKVSHSYGYGLLDAGAMVALA--QNWTTVAPQRKCIIEI-LAEPKDIG----KRLEVRKTVTACLG--EPNHISRLEHVQARLTLSYNRRGDLAIHLISPMGTRSTLLAARPHDYSA-DGFNDWAFMTTHSWDEDPSGEWVLEIENTS----EANNYGTLTKFTLVLYGT-------------------------------------------------------------------------------------------------ASEGLSAPPESS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------GCKTLTSSQACVVCEEGFSLHQKSCVQRCPPGFTPQVL----DTHYSTENDVEIIRAS--------------------------------------VCTPCHASCATCQGPAPTDCLSCPSHASLDP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VEQTCSRQSQSSRESRPQQPPPALRPEVEVEPRLRAG-----------------------LASHLPEVLAGLSCLIIALIFGIVFLFLHRCS----GFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEGRGERTAFIKDQSAL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09958-1", "uniprot_id": "FURIN_HUMAN", "id": "P09958-1", "name": "Furin", "aln": "---------------------------------------------------------------------------------------------------------------------------MELRPWLLWVVAATGTLVL----LAADAQ--------------------------------------------------------------------------------------------------------------------GQKVFTNTWAVRIPGGPAV--ANSVARKHGFLNLG-QIFGD--YYHFWHRGVTKRSLSP---HRPRHSRLQREPQVQWLEQQVAKRRTKRDVY---------------------------------------------------QEPTDPKFPQQWYLSGVTQR------DLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDG-EVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ-NEKQIVTTDLR------QKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNAND----WATNGVGRKVSHSYGYGLLDAGAMVALA--QNWTTVAPQRKCIIDI-LTEPKDIG----KRLEVRKTVTACLG--EPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSA-DGFNDWAFMTTHSWDEDPSGEWVLEIENTS----EANNYGTLTKFTLVLYGT-------------------------------------------------------------------------------------------------APEGLPVPPESS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------GCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVL----DTHYSTENDVETIRAS--------------------------------------VCAPCHASCATCQGPALTDCLSCPSHASLDP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VEQTCSRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGL----------------------LPSHLPEVVAGLSCAFIVLVFVTVFLVLQLRS----GFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEGRGERTAFIKDQSAL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P30432-1", "uniprot_id": "FUR2_DROME", "id": "P30432-1", "name": "Furin-like protease 2", "aln": "----------------------------------MSNTTRSSRVTIGRIGTTPQITDPWSSGLEKQRPSRCGGPKSLAEPTYRKIGRRKMMLHMRVHDPGTTVTQRAKETATAKLNRIYLCTFNRMAQSCIYFVLFLVILSPNTSCALRSSAGETQNYVGILSNDSATTTYDVSSLHSSRRTNPPSSSSSSSSNVDVDYRNDRELHKVDLVGLGGERAGQAETISGGKYDYNYENTHTNASAKDEIVERQSNSLDFDGVDMFGAFSIPEEAIYTNEFAVNIPAGKQM--ADVIATKHGFINRG-QIGSLDNYYLFQHHHVSKRSLRS---SRKHQGALKSENEVKWMQQQHEKVRRKRDGPYQDLPTYSPYNLLRQHGGYVVDPNPHLSFSPESISLASHSQRMEYRDVSSHFIFPDPLFKEQWYLNGGAKDG----LDMNVGPAWQKGYTGKGVVVSILDDGIQTNHPDLAQNYDPEASFDINGNDSDPTP--QDNGDNKHGTRCAGEVAAVAFNNFCGVGVAYNASIGGVRMLDG-KVNDVVEAQALSLNPSHIDIYSASWGPEDDGSTVDGPGPLARRAFIYGVTSGRQGKGSIFVWASGNGGRYTDSCNCDGYTNSIFTLSISSATQAGFKPWYLEECSSTLATTYSSGTPGHDKSVATVDMDGSLRPDHICTVEHTGTSASAPLAAGICALALEANPELTWRDMQYLVVYTSRPAPLEKENG---WTLNGVKRKYSHKFGYGLMDAGAMVSLA--EQWTSVPPQHICKSRE-NNEDRKIDGAYGSTLSTHMDVNGCAG--TINEVRYLEHVQCRITLRFFPRGNLRILLTSPMGTTSTLLFERPRDIVK-SNFDDWPFLSVHFWGEKAEGRWTLQVINGGR--RRVNQPGILSKWQLIFYGTSTQPMRLKSELLNSSPQLRSPSSSNPFLFPSASNIGQPANEGGNFNTDSFASYLNYQNIFSSAGSDPEPATATLDGQNVTAAIAGGSSAESLGFTASAAQLVAAPETRDGDKKILHSCDAECDSSGCYGRGPTQCVACSHYRL-----DNTCVSRCPPRSFPNQVGI-CWPCHDTCETCAGAGPDSCLTCAPAHLHVIDLAVCLQFCPDGYFENSRNRTCVPC-EPNCASCQDHPEYCTSCDHHLVMHEHKCYSACPLDTYETEDN-KCAFCHSTCATCNGPTDQDCITCRSSRYAWQNKCLISCPDGFYADKK----RLECMPCQEGCKTCTSNGVCSECLQNWTLNKRDKCIVSGSEGCSESEFYSQVEGQCRPCHASCGSCNGPADTSCTSCPPNRLLEQSRCVSGC-----------------------------------------------------------------------------------------------------------------------------------------------------------REGFFVEAGSLCSPCLHTCSQCVSRTNCSNCSKGLELQNGECRTTCADGYYSDR--GICAKCYLSCHTCSGPRRNQCVQCPAGWQLAAGECHPECPEGFYK--------------------------------SDFGCQKCHHYCKTCNDAGPLACTSCPPHSMLDGGLCME-CLSSQYYDTTSATCKTCHDSCRSCFGPGQFSCKGCVPPLHLDQLNSQCVSCCQNQTLAEKTSSAACCNCDGETGECKATSTGGKRRTVVGSGSAYKSSESKHGSFENDGNAREF------------VLRLDSPLTAITAIAVAICLLIITIFSIIFAVLQRNSNHVSRNSVRYRKIANTSSGRRKNLSAKPTSDARFIFNIGEDDDTDGDNSDDELDGNVGTDINNRIV-----------------YDRKGNDHGHEFYIESTNDIDAIEFHCNGAGAQKAETQLQRCNANGDDDDILHYDRHTNAERKNHPSSTTSRTNIRS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBC7-1", "uniprot_id": "NEC2_DROME", "id": "Q9VBC7-1", "name": "Neuroendocrine convertase 2", "aln": "-----------------------------------------------------------------------------------------------------------------------MAAATWSWLLAPFLLLHWASAGAGGGAGGSGAG------------------------------------------------------------------------------------------------------------------LSGPAVFTSSFLVRFRRGVDNSFAHDVADKYGFDNLGPLVGADGHEYHFKHRTLPHARSRR---SLTHTRALKSHPAVHTAVQQPGFKRVKRGLRPAVPAIHG-----------------------------MKFDLKVGEGNRIDEEPTDPYFPMQWYLKNTGQNGGKVRLDLNVQAAWAQGITGKNVTTAIMDDGVDYMHPDLKFNYNAEASYDFSSNDPFPYPRYTDDWFNSHGTRCAGEVAAARDNGICGVGVAYDSKIAGIRMLDQPYMTDLIEANSMGHEPHKIHIYSASWGPTDDGKTVDGPRNATMRAIVQGVNEGRNGLGNIYVWASGDGG-EEDDCNCDGYAASMWTISINSAINDGQNAHYDESCSSTLASTFSNGAKDPNTGVATTDLYG------KCTTTHSGTSAAAPEAAGVFALALEANPQLTWRDIQHLTVLTSKRNSLFDAKNRFHWTMNGVGLEFNHLFGFGVLDAGAMVTLS--KQWHSVPPRYHCEAGE-LTQPQAIVMG--RSLFWEIKTDACKG--TDTEVNYLEHVQAVISANASRRGDLELFLTSPMGTKSMILSRRANDDDHRDGFTKWPFMTTHSWGEYPQGTWKLEARFNS----PQTRHGNLLEWSLVLHGT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KEAPYRTLHPSSPHSKLAIVKKAHEDKKMK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P63239-1", "uniprot_id": "NEC1_MOUSE", "id": "P63239-1", "name": "Neuroendocrine convertase 1", "aln": "---------------------------------------------------------------------------------------------MEQRG-----------------------WTLQCTAFAFFC----------VWCALNSVKAKR--------------------------------------------------------------------------------------------------------------------QFVNEWAAEIPGGQE--AASAIAEELGYDLLG-QIGSLENHYLFKHKSHPRRSRRS---ALHITKRLSDDDRVTWAEQQYEKERSKRSVQ-----KDSALDL-----------------------------------------FNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWEKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDLTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDG-IVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDY-TDQRITSADLH------NDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLASNPG---WKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECVVKDNNFEPRALKAN--GEVIVEIPTRACEG--QENAIKSLEHVQFEATIEYSRRGDLHVTLTSAVGTSTVLLAERERDTSP-NGFKNWDFMSVHTWGENPVGTWTLKITDMS---GRMQNEGRIVNWKLILHGTSS-----------------------------------------------------------------------------------------------QPEHMKQP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVYTSYNTVQN---DRRGVEKMVNVV--------------EKRPTQKSLNGNL---------------------------------LVPKNSSSSNVEGRRDEQVQG------TPSKAMLRLLQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SAFSKNALSKQSPKKSPSAKLSIPYESFYEALEKLN----------------------------KPSKLEGSEDS-----------LYSDYVDVFYNTKPYKHRDDR--------LLQALMDILNEEN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28840-1", "uniprot_id": "NEC1_RAT", "id": "P28840-1", "name": "Neuroendocrine convertase 1", "aln": "---------------------------------------------------------------------------------------------MKQRG-----------------------WTLQCTAFTLFC----------VWCALNSVKAKR--------------------------------------------------------------------------------------------------------------------QFVNEWAAEIHGGPE--AASAIAEELGYDLLG-QIGSLENHYLFKHKNHPRRSRRS---ALHITKRLSDDDRVIWAEQQYEKERRKRSVP-----RDSALNL-----------------------------------------FNDPMWNQQWYLQDTRMTASLPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDG-IVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDY-TDQRITSADLH------NDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPG---WKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECIIKDNNFEPRALKAN--GEVIVEIPTRACEG--QENAINSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSP-NGFKNWDFMSVHTWGENPVGTWTLKVTDMS---GRMQNEGRIVNWKLILHGTSS-----------------------------------------------------------------------------------------------QPEHMKQP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVYTSYNTVQN---DRRGVEKMVNVV--------------EEKPTQNSLNGNL---------------------------------LVPKNSSSSSVEDRRDEQVQG------APSKAMLRLLQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SAFSKNTPSKQSSK-IPSAKLSVPYEGLYEALEKLN----------------------------KPSQLEDSEDS-----------LYSDYVDVFYNTKPYKHRDDR--------LLQALMDILNEKN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29120-1", "uniprot_id": "NEC1_HUMAN", "id": "P29120-1", "name": "Neuroendocrine convertase 1", "aln": "---------------------------------------------------------------------------------------------MERRA-----------------------WSLQCTAFVLFC----------AWCALNSAKAKR--------------------------------------------------------------------------------------------------------------------QFVNEWAAEIPGGPE--AASAIAEELGYDLLG-QIGSLENHYLFKHKNHPRRSRRS---AFHITKRLSDDDRVIWAEQQYEKERSKRSAL-----RDSALNL-----------------------------------------FNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDG-IVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDY-TDQRITSADLH------NDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPG---WKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRALKAN--GEVIIEIPTRACEG--QENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSP-NGFKNWDFMSVHTWGENPIGTWTLRITDMS---GRIQNEGRIVNWKLILHGTSS-----------------------------------------------------------------------------------------------QPEHMKQP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVYTSYNTVQN---DRRGVEKMVDPG--------------EEQPTQENPKENT---------------------------------LVSKSPSSSSVGGRRDELEEG------APSQAMLRLLQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SAFSKNSPPKQSPKKSPSAKLNIPYENFYEALEKLN----------------------------KPSQLKDSEDS-----------LYNDYVDVFYNTKPYKHRDDR--------LLQALVDILNEEN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P26016-1", "uniprot_id": "FUR11_DROME", "id": "P26016-1", "name": "Furin-like protease 1, isoforms 1/1-X/2", "aln": "MKNDVVRWSRQPTSNTTNSSSSSRSDSNSTHKHRSKSNKLNARQLGSNAARSCQQRSSVATTLEDEQQTIIECDIGNFNFDCNLFKTSFLTQHKQKRSGKSSSKSKSNRSRPLAKTKAVFLLALQFSAVVFLCNINVGFVAGSVATAASSAGGSSPAAPSSAPSSPPTVAVPPPPPPSSALKVDPNGQSPVLPPYVLDYETGGK------------------------------------------AKLTPNNGKFGQSGSSGSNNNHIVGHYTHTWAVHIPNGDNG-MADAVAKDHGFVNLG-KI--FDDHYHFAHHKVSKRSLSP---ATHHQTRLDDDDRVHWAKQQRAKSRSKRDFIRMRPSRTSSRAMS----------------------------------MVDAMSFNDSKWPQMWYLNRG------GGLDMNVIPAWKMGITGKGVVVTILDDGLESDHPDIQDNYDPKASYDVNSHDDDPMPHYDMTDSNRHGTRCAGEVAATANNSFCAVGIAYGASVGGVRMLDG-DVTDAVEARSLSLNPQHIDIYSASWGPDDDGKTVDGPGELASRAFIEGTTKGRGGKGSIFIWASGNGGREQDNCNCDGYTNSIWTLSISSATEEGHVPWYSEKCSSTLATTYSSGGQ-GEKQVVTTDLH------HSCTVSHTGTSASAPLAAGIAALVLQSNQNLTWRDLQHIVVRTAKPANLK-DPS---WSRNGVGRRVSHSFGYGLMDAAEMVRVA--RNWKAVPEQQRCEINAPHVD-KVIPPR--THITLQLTVNHCR------SVNYLEHVQAKITLTSQRRGDIQLFLRSPANTSVTLLTPRIHDNSR-SGFNQWPFMSVHTWGESPQGNWQLEIHNE----GRYMGHALLREWSLIFYGTTQSI-------------------------------------------------------------GPNDPISVPKPSGSEATTPNSSSTTSNLHQAYSPQYPRIPPNNFGSS--------------------------------------------------------------------------------------------------------------------------------------------------------PSGGSKLPLGKVPPPNKSSYVTNNPLLNSAPPKQGYQQISATYGVILGKANGKSNNNSKEKTNNKGNKSN---------------------------------NGNKGKSGGSSGNRKEQTTQSTIIQTSTSKNKYYRISQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QQQQKNNKQDRNGVQTQRPKANSGEKSYDEKSRKVVGEITTNSGN---------------GSIKAAKQVKESTTTSSNSRIPKLFERYEKIQAIFPELEPYENSSPKGKPKQAKQGKQFEVDLFKPTNGGNSRQGNTKKSPSVPPPSQTMATLSILPILPAGGSSFLPDQKILKKQQLLMAAAGVMAPAQVEVEMEEVHATPDYEARKDQRKEVNGPNAQITQWDMIFYGTETPAQPDDVANPSQSNQFNLYGNDMAHNDVEYDSTGQWRNMQQVGEVGMTRD------HSNTAACLKWSDRKCLGLSLLFFMIMQVFFLNFKHANDNNNKNKNNIIKCIR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q61139-1", "uniprot_id": "PCSK7_MOUSE", "id": "Q61139-1", "name": "Proprotein convertase subtilisin/kexin type 7", "aln": "-----------------------------------------------------------------------------------------------------MPKGRQKVPHLDAHLGLPICLWLELA-IFFLVPQVMGLSEAGGLDILGTGGL-------------------------------------------------------------------------------------------------------------------SWAVHLDSLEGERKEESLTQQADAVAQAAGLVNAG-RIGELQGHYLFVQPTGHRQAMEVEAMRQQAEAVLARHEAVRWHSEQTLLKRAKRSIH-----------------------------------------------------FNDPKYPQQWHLNNRRSPGR----DINVTGVWERNVTGRGVTVVVVDDGVEHTVQDIAPNYSPEGSYDLNSNDPDPMPHPDEENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIAGIRVLDG-PLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVMAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFSGGDK-MLRSIVTTDWDLQKG--TGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTAIQYEDHHAD----WLTNEAGFSHSHQHGFGLLNAWRLVNAA--KIWTSVPYLASYVSPMLKENKAVPRSPHSLEVLWNVSRTDLEM----SGLKTLEHVAVTVSITHPRRGSLELKLFCPSGMMSLIGAPRSMDSDP-NGFNAWTFSTVRCWGERARGVYRLVIRDVG---DEPLQMGILQQWQLTLYGSMWSP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDIKDRQSLLESAMSGKYLHDGFTLPCPPGLKIPEEDGYTITPNTLKTLVLVGCFS-------------------------------------VFWTIYYMLEVCLSQRNKASTHGCRKGCCPWAPR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RQNSKDAGTALESMPLCSSKDLDGVDSEHGDCTTAS-----------------------SFLAP----------------ELDCPPHQPPDLLQGKSGQIC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62849-1", "uniprot_id": "PCSK7_RAT", "id": "Q62849-1", "name": "Proprotein convertase subtilisin/kexin type 7", "aln": "-----------------------------------------------------------------------------------------------------MPKGRQKVPRLDARLGLPICLCLELA-IFFLVPQVMGLTEAGGLDTLGAGGL-------------------------------------------------------------------------------------------------------------------SWAVHLDSLEGERKEESLIQQANAVAQAAGLVNAG-RIGELQGHYLFVQPAGHGQAMEAEAMRQQAEAVLAKHEAVRWHSEQRLLKRAKRSIH-----------------------------------------------------FNDPKYPQQWHLNNRRSPGR----DINVTGVWERNVTGRGVTVVVVDDGVEHTVQDIAPNYSPEGSYDLNSNDPDPMPHPDEENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIAGIRVLDG-PLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVMAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFSGGDK-MLRSIVTTDWDLQKG--TGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTATQYEDHRAD----WLTNEAGFSHSHQHGFGLLNAWRLVNAA--KIWTSVPYLASYVSPMLKENKAVPRSPHSLEVLWNVSRTDLEM----SGLKTLEHVAVTVSITHPRRGSLELKLFCPSGMMSLIGAPRSMDSDP-NGFNDWTFSTVRCWGERARGVYRLVIRDVG---DEPLQVGILQQWQLTLYGSTWSP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDIKDRQSLLESAMSGKYLHDDFTLPCPPGLKIPEEDGYSITPNTLKTLVLVGCFS-------------------------------------VFWTIYYMLEVCLSQRSKASTHGCRRGCCPWPPQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SQNSKEVGTALESMPLCSSKDLDGVDSEHGDCTTAS-----------------------SLLAPELLGEADWSLSQNSKSDLDCPPHQPPDLKD---GQIC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16549-1", "uniprot_id": "PCSK7_HUMAN", "id": "Q16549-1", "name": "Proprotein convertase subtilisin/kexin type 7", "aln": "-----------------------------------------------------------------------------------------------------MPKGRQKVPHLDAPLGLPTCLWLELAGLFLLVPWVMGLAGTGGPDGQGTGGP-------------------------------------------------------------------------------------------------------------------SWAVHLESLEGDGEEETLEQQADALAQAAGLVNAG-RIGELQGHYLFVQPAGHRPALEVEAIRQQVEAVLAGHEAVRWHSEQRLLRRAKRSVH-----------------------------------------------------FNDPKYPQQWHLNNRRSPGR----DINVTGVWERNVTGRGVTVVVVDDGVEHTIQDIAPNYSPEGSYDLNSNDPDPMPHPDVENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIAGIRVLDG-PLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVIAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFSGGDK-MLRSIVTTDWDLQKG--TGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTATRYEDRRAE----WVTNEAGFSHSHQHGFGLLNAWRLVNAA--KIWTSVPYLASYVSPVLKENKAIPQSPRSLEVLWNVSRMDLEM----SGLKTLEHVAVTVSITHPRRGSLELKLFCPSGMMSLIGAPRSMDSDP-NGFNDWTFSTVRCWGERARGTYRLVIRDVG---DESFQVGILRQWQLTLYGSVWSA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDIRDRQRLLESAMSGKYLHDDFALPCPPGLKIPEEDGYTITPNTLKTLVLVGCFT-------------------------------------VFWTVYYMLEVYLSQRNVASNQVCRSGPCHWPHR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SRKAKEEGTELESVPLCSSKDPDEVETESRGPPTTS-----------------------DLLAPDLLEQGDWSLSQN-KSALDCP-HQHLDVPHGKEEQIC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P8P5-1", "uniprot_id": "A0A8M1P8P5_DANRE", "id": "A0A8M1P8P5-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------MASCSSRVCLG--------LYPLLLLFSSS---SSSCAPGR-------------------------------------------------------------------------------------------------------------------SWAVQLQ-PDSLSSAGSPDLLAQAVAQDVGLRSHG-QIGQLEGHYLLCQDPAQGED------WRWMEAALDRHPHVAWHSQENVLRRSKRSVH-----------------------------------------------------FNDPKFPSQWHLHNDMKRGM----DINVTGVWERNITGAGVTVVVVDDGIQHNLADIQPNYSPEGSYDLNSNDPDPMPHPDGPSDNHHGTRCAGEIAAVSNNSFCAVGVAYGSRVAGIRVLDG-PLTDSMEAIAFNKHYQVNDIYSCSWGPDDDGRTVDGPHPLGKAALQHGVIAGRKGFGSIFIVASGNGGQNQDNCNYDGYANSIYTVTIGAVDESGRKPTYAEECASMLAVTFSSGNT-PLRSIVTSDWSLQSG--TGCTSGHTGTSAAAPLAAGMVALMLQVRPCLSWRDVQHIITYTATQH-DLQAD----WVTNGAGFHHSHKYGFGLLNAWRLVNAA--KVWESVPFLVSYQSPVLRVNEVITTSTN-LTQTWNVSESDLQR----SGMQTLEHVSVTLSIQHPRRGNLQILLLCPSGISSLIGARRALDVDS-AGLTDWTFSTVRCWGEQAEGQYSLLIMD-----DAPLSSGILKSWKLTLYGSSLSH----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QQVTDRQRVVEEAMSGHYLSSSFSLPCPPGIDVPAEIVNPFTSSSLKSLLLLGCFT-------------------------------------LFWSLYYTLEVVLTHWDWRG--GCVRGRDGDAGY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SRLSRDE----------AQTDPQQVEVLLETHSQDK-----------------------VLLIADT--------------------HT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13134-1", "uniprot_id": "KEX2_YEAST", "id": "P13134-1", "name": "Kexin", "aln": "---------------------------------------------------------------------------------------------------------------MKVRKYITLCFWWAFSTSALVSSQQIPLKDHTSRQYFAVES----------------------------------------------------------------------------------------------------------------------NETLSRLEEMHPNWKYEHDVRGLPNHYVFSKELLKLGKRSSLEELQGDNNDHILSVHDLFPRNDLFKRLPVPAPPMDSSLLPVKEAEDKLS-----------------------------------------------------INDPLFERQWHLVNPSFPGS----DINVLDLWYNNITGAGVVAAIVDDGLDYENEDLKDNFCAEGSWDFNDNTNLPKPR---LSDDYHGTRCAGEIAAKKGNNFCGVGVGYNAKISGIRILSG-DITTEDEAASLIYGLDVNDIYSCSWGPADDGRHLQGPSDLVKKALVKGVTEGRDSKGAIYVFASGNGGTRGDNCNYDGYTNSIYSITIGAIDHKDLHPPYSEGCSAVMAVTYSSGSG---EYIHSSDIN------GRCSNSHGGTSAAAPLAAGVYTLLLEANPNLTWRDVQYLSILSAVGLEKNADG---DWRDSAMGKKYSHRYGFGKIDAHKLIEMS--KTWENVNAQTWFYLPTLYVSQSTNSTEETLESVITISEKSLQD----ANFKRIEHVTVTVDIDTEIRGTTTVDLISPAGIISNLGVVRPRDVSS-EGFKDWTFMSVAHWGENGVGDWKIKVKTTEN-----GHRIDFHSWRLKLFGESIDS-------------------------------------------------------------------------------------------SKTETFVFGNDKEE------------------------------------------------------------------------------------------------------------------------------------------------------------------------VEPAATESTVSQYSASSTSISISATSTSSISIGVETSAIPQTTTASTDPDSDPNTPK-------------------------------------KLSSPRQAMHYFLTIFLIGATFLVLYFMFFMKSR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RRIRRSRAETYEFDIIDTDSEYDSTLDNGTSGITEPEE---------------VEDFDFDLSDEDHLASLSSSENGDAEHTIDSVLTNENPFSDPIKQKFPNDANAESASNKLQELQPDVPPSSGRS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : : . . : *. : *:: :: : * . :* .:. ::***:: *: *: . .* *... * * : ******* :: * * .*:.:.: :.*:*:*. :. ** :. .***.**** *** ::** *: * ** . * ::: ***:** * *. ***: *: ::::.: . . . * * *:: :: ::*.* : : * *: * ***.:** .**: :* *: . *:***:*:: :: * . . .*:* ::* :: : . * . . :**. ** : * .. . : * * . * * : *.* * : : : * :.* ", "identical_positions": 97, "similar_positions": 121, "identity": "4.17%" }, { "cls_id": "homologset.agr.SGD:S000005183", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70645-1", "uniprot_id": "BLMH_RAT", "id": "P70645-1", "name": "Bleomycin hydrolase", "aln": "-------------------------------------------------------------------------------------MNNAGLNSEK--------VAALIQKLN----SDPQFVLAQNVGTTHDLLDICLKRATVQG-AQHVFQHVVPQEGKPVTNQKSSGRCWIFSCLNVMRLPFMKKFNI-EEFEFSQSYLFFWDKVERCYFFLNAFVDTAQKKEPEDGRLVQYLLMNPTNDGGQWDMLVNIVEKYGVVPKKCFPES-HTTEATRRMNDILNHKMREFCIRLRNLVHSGATKGEISSTQDAMME-EIFRVVCICLGNP----PETFTWEYRDKDKNYHKVGPITPLQFYKEHVKPLFNMEDKICFVNDPRPQHKYNKLYTVDYLSNMVGGRKTLYNNQPIDFLKKMVAASIRDGEAVWFGCDVGKHFNGKLGLSDMNVYDHELVFGVSLKN-MNKAERLAFGESLMTHAMTFTAVSEKDDQEGAFVKWRVENSWGEDHGHKGY----------------------LCMTDEWFSEYVYEVVVDKKHVPEEVLAVLE---QEPIVLPAWDPMGALA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R016-1", "uniprot_id": "BLMH_MOUSE", "id": "Q8R016-1", "name": "Bleomycin hydrolase", "aln": "-------------------------------------------------------------------------------------MNNAGLNSEK--------VSALIQKLN----SDPQFVLAQNVGTTHDLLDICLRRATVQG-AQHVFQHVVPQEGKPVTNQKSSGRCWIFSCLNVMRLPFMKKFNI-EEFEFSQSYLFFWDKVERCYFFLNAFVDTAQKKEPEDGRLVQYLLMNPTNDGGQWDMLVNIVEKYGVVPKKCFPES-HTTEATRRMNDILNHKMREFCIRLRNLVHSGATKGEISSTQDAMME-EIFRVVCICLGNP----PETFTWEYRDKDKNYHKIGPITPLQFYKEHVKPLFNMEDKICFVNDPRPQHKYNKLYTVDYLSNMVGGRKTLYNNQPIDFLKKMVAASIKDGEAVWFGCDVGKHFNGKLGLSDMNVYDHELVFGVSLKN-MNKAERLAFGESLMTHAMTFTAVSEKDNQEGTFVKWRVENSWGEDHGHKGY----------------------LCMTDEWFSEYVYEVVVDKKHVPEEVLAVLE---QEPIVLPAWDPMGALAE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13867-1", "uniprot_id": "BLMH_HUMAN", "id": "Q13867-1", "name": "Bleomycin hydrolase", "aln": "-------------------------------------------------------------------------------------MSSSGLNSEK--------VAALIQKLN----SDPQFVLAQNVGTTHDLLDICLKRATVQR-AQHVFQHAVPQEGKPITNQKSSGRCWIFSCLNVMRLPFMKKLNI-EEFEFSQSYLFFWDKVERCYFFLSAFVDTAQRKEPEDGRLVQFLLMNPANDGGQWDMLVNIVEKYGVIPKKCFPES-YTTEATRRMNDILNHKMREFCIRLRNLVHSGATKGEISATQDVMME-EIFRVVCICLGNP----PETFTWEYRDKDKNYQKIGPITPLEFYREHVKPLFNMEDKICLVNDPRPQHKYNKLYTVEYLSNMVGGRKTLYNNQPIDFLKKMVAASIKDGEAVWFGCDVGKHFNSKLGLSDMNLYDHELVFGVSLKN-MNKAERLTFGESLMTHAMTFTAVSEKDDQDGAFTKWRVENSWGEDHGHKGY----------------------LCMTDEWFSEYVYEVVVDRKHVPEEVLAVLE---QEPIILPAWDPMGALAE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X2JEJ0-1", "uniprot_id": "X2JEJ0_DROME", "id": "X2JEJ0-1", "name": "Bleomycin hydrolase", "aln": "MFWAVRRSVTQIKINSPKLSQNPNTYRNRIPYPQQQQEPAMYYSKESVQTHTISGERCQSHLLAADNNSGSGGGGSGGGGAGNNNSANSGKNSTHRFAETSVITNQLLEKWRKNFYSEPKNLLAQNVCSRVDPFDVCLSRKALET-TNHVFNYKVETEGKPVTNQRSSGRCWLFAALNCIRLPFMKNYNL-DEFEFSQAFLFYWDKIERCNYFLNNVVKTAQRGEKVDGRLVSFLLLDPTSDGGQWDMLVNLITKHGLMPKKCFPES-FSCESSLRMNAILKSKLREYARNLRVLMEKNPTDEEIACKIQEQMA-EIYKVVGICLGIP----SETFTWEYYDKSKNYQSIGPVSSLEFYERYVKPHFNVEDKVCLVTDPRPTSSYDQAYTVDCLGNVVGGRPVLYNNQSVELLLAVVTKSLKAGEAVWFGCEVSKRFASKQGIEDVDVHDFKLVFDIDIQTTFSKADRLIYGESAMTHAMVFTAVS--VDKSGVAQKLRVENSWGEDRGEKGY----------------------LVMNADWFREFGFEVVVDKKYVPEDVLRVFD---MDPIVLPAWDPMGTLAQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q01532-1", "uniprot_id": "BLH1_YEAST", "id": "Q01532-1", "name": "Cysteine proteinase 1, mitochondrial", "aln": "-------------------------------------------MLPTSVSRSLYLKTFRSHLLR--------------APQIVLKRMSSSIDISK--------INSWNKEFQ----SDLTHQLATTVLKNYNADDALLNKTRLQKQDNRVFNTVVSTDSTPVTNQKSSGRCWLFAATNQLRLNVLSELNL-KEFELSQAYLFFYDKLEKANYFLDQIVSSAD--QDIDSRLVQYLLAAPTEDGGQYSMFLNLVKKYGLIPKDLYGDLPYSTTASRKWNSLLTTKLREFAETLRTALKERSADDSIIVTLREQMQREIFRLMSLFMDIPPVQPNEQFTWEYVDKDKKIHTIK-STPLEFASKYAK--LDPSTPVSLINDPR--HPYGKLIKIDRLGNVLGGDAVIYLNVDNETLSKLVVKRLQNNKAVFFGSHTPKFMDKKTGVMDIELWNYP-AIGYNLPQ--QKASRIRYHESLMTHAMLITGCH-VDETSKLPLRYRVENSWGKDSGKDGL----------------------YVMTQKYFEEYCFQIVVDINELPKELASKFTSGKEEPIVLPIWDPMGALAK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A1ZBU9-1", "uniprot_id": "A1ZBU9_DROME", "id": "A1ZBU9-1", "name": "Bleomycin hydrolase", "aln": "--------------------------------------------------------------------------------------MSFLLTEPQ--------WSAWYSAFY----ASSMNRLAQNVCTAQDPITVCLRSEADLCSVPSGVKTWIELSRQ--GKATTGGPGWICTGLDLLCQEMDRKLPLPLDFELSAAHLFFWHKLERCNYFLWTVADLLMRCEPLDGRCFRNLIKNPVPDGGNWQMFVNLVKKYGVMPKKCYLHS---TQRTTKMNLILKSKLREYASMLHAQFTFNGNGCRLPDLIQEMIP-HLFKVICICLGEP----PKVFTWSFYDHKKRYQCLNDMTAVHFYEVMVGCTVNLDAFVCLGHDPRISSSYHSNYQVANSSNMMGGKPHRYNNQSMDIIMQIMVTSLEGDKPVWMACDIRRAISLKSGPLSLRSHQFDLLFGFKVGESLTKAERLDYRASRRDAALLLTSVGLDTLKQPVQFRFINASTIGESPATGGLNEHDVDEKVTKALRKKSVKPPDNKLDAEWLREYAFEIVVHEKFVPSGVLHAAR--IHKWKELPAWDPMGALLN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . :. ** .* . : * .: : . : :.* *: : : : . : : :**:* :.**::.*:*:. :** ... : *.* . *: *. ***::.*::*:: *:*::**. : . : : * :*. *:**:. *: . : : .::::: : :. * : ***.: *:.*. : : :.:.* . .: . :.: *** * . : .*::** * * : : ::. :. .:.*::... : : * * .: :. :. .: **.*: : * *: :*. . : .: *:. . * : .:: *: :::**. : :*. : . ** *****:* ", "identical_positions": 73, "similar_positions": 151, "identity": "12.46%" }, { "cls_id": "homologset.agr.SGD:S000005184", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2YDU6-1", "uniprot_id": "NARF_RAT", "id": "Q2YDU6-1", "name": "Nuclear prelamin A recognition factor", "aln": "MKCEHCTRK-------------ECSKKSKTDDQENVSVDVP------SPAQENEEKGEFHKLADAK-IFLSDCLACDSCVTVEEGVQLSQQSAKDFFHVLNLNKRCDTSK----HKVLVVSVCPQSLPYFAAKFNLSVTDASRRLCGFLKS-LGVHYVFDTTIAADFSILESQKEFVRRYHQHSEE-QRELPMLTSACPGWVRYAERVLGRPIIPYLCTAKSPQQVMGSLVKDYFARQQSLAPEKIFHIVVAPCYDKKLEALREGLSPTLNGARGTDCVLTSGEIAQIMEQSDLSVKDIA---VDTLFGDVK-EMAVRRHDGVSSDGHLAHVFRHAAKELFGEHVE-EITYRALRNKDFHEVTLEKNGEVLLRFAAAYGFRNIQNMIMKLKKGKFP-----------------------------------YHFVEVLACPRGCLNGRGQAQTEDGHTDRALLQQMEGIYSGIPVWPPESSTHVQELYQEWLEGTESPKVQEVLHTSYQS---LEPCTDSLDIKW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CYQ7-1", "uniprot_id": "NARF_MOUSE", "id": "Q9CYQ7-1", "name": "Nuclear prelamin A recognition factor", "aln": "MKCEHCTRK-------------ECSKKSKTDDQENVSSDGAQPSDGASPAKESEEKGEFHKLADAK-IFLSDCLACDSCVTVEEGVQLSQQSAKDFLHVLNLNKRCDTSK----HRVLVVSVCPQSLPYFAAKFNLSVTDASRRLCGFLKS-LGVHYVFDTTIAADFSILESQKEFVRRYHQHSEE-QRELPMLTSACPGWVRYAERVLGRPIIPYLCTAKSPQQVMGSLVKDYFARQQNLSPEKIFHVVVAPCYDKKLEALREGLSTTLNGARGTDCVLTSGEIAQIMEQSDLSVKDIA---VDTLFGDMK-EVAVQRHDGVSSDGHLAHVFRHAAKELFGEHVE-EITYRALRNKDFHEVTLEKNGEVLLRFAAAYGFRNIQNMIQKLKKGKLP-----------------------------------YHFVEVLACPRGCLNGRGQAQTEDGHTDRALLQQMEGIYSGIPVRPPESSTHVQELYQEWLEGTESPKVQEVLHTSYQS---LEPCTDGLDIKW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHQ1-1", "uniprot_id": "NARF_HUMAN", "id": "Q9UHQ1-1", "name": "Nuclear prelamin A recognition factor", "aln": "MKCEHCTRK-------------ECSKKTKTDDQENVSADAP------SPAQENGEKGEFHKLADAK-IFLSDCLACDSCMTAEEGVQLSQQNAKDFFRVLNLNKKCDTSK----HKVLVVSVCPQSLPYFAAKFNLSVTDASRRLCGFLKS-LGVHYVFDTTIAADFSILESQKEFVRRYRQHSEE-ERTLPMLTSACPGWVRYAERVLGRPITAHLCTAKSPQQVMGSLVKDYFARQQNLSPEKIFHVIVAPCYDKKLEALQESLPPALHGSRGADCVLTSGEIAQIMEQGDLSVRDAA---VDTLFGDLK-EDKVTRHDGASSDGHLAHIFRHAAKELFNEDVE-EVTYRALRNKDFQEVTLEKNGEVVLRFAAAYGFRNIQNMILKLKKGKFP-----------------------------------FHFVEVLACAGGCLNGRGQAQTPDGHADKALLRQMEGIYADIPVRRPESSAHVQELYQEWLEGINSPKAREVLHTTYQS---QERGTHSLDIKW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DHP6-1", "uniprot_id": "NARF_DANRE", "id": "Q6DHP6-1", "name": "Nuclear prelamin A recognition factor", "aln": "MSEVKIGRKK-----------EKCENCTKQCNKKQSDESIN------SLQEKGVASGEVRESTSVQQVLLSACLSCDGCISEDEGKRISQQNLDEINHVLALNKKCDTSK----HKILVVSVCPQSVPFFAVKFQLDVSAAAQKLCGFLKS-VGVHYVFDTTIAASFSILESQREFVQRYRRKHHD-ANAMPMFTSSCPGWIRYAERVLGSVVTPHICTARSPQQIMGSLVKNFFARQQKLTPEQVFHVVVAPCFDKKLEAVRDEFYNSILESRDVDCVLTSGEILHLMEQSKVTVEEVDSAPLDHVIGEIS-DSGLTRHDGRGSEGFLEHIFKHAAKEIFGLDVQ-DIVYKTLRNRDFQEVALERDGETLLQFAAVYGFRNIQTLVHRMRKGKVP-----------------------------------YQLIEVLSCPGGCLSGRGQAEGEGGRPDRTLVQQMEEHYSSLPVRLPETNPEVQRLYQDWLDGHDSPHAQQSLHTQYKDHTHLPAHITNPDIQW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7TMW6-1", "uniprot_id": "CIAO3_MOUSE", "id": "Q7TMW6-1", "name": "Cytosolic iron-sulfur assembly component 3", "aln": "MASPFSGALQLTDLDDFIGPSQNCIKPVKVAKKPGSGIAKIHIEDDGSYFQVNQD-GRTQKLEKAK-VSLNDCLACSGCVTSAETVLITQQSHEELRKVLDANKEAAPGQ----QRLVVVSISPQSRASLAARFRLDPTDTARKLTSFFKK-IGVHFVFDTAFARNFSLLESQKEFVQRFREQANS-REALPVLASACPGWICYAEKTHGNFILPYISTARSPQQVMGSLVKDFFAQQQLLTPDKIYHVTVMPCYDKKLEASRPDFFNQEYQTRDVDCVLTTGEVFRLLEEEGVSLTELEPAPLDGLTSSVS-AEEPSSHRGGGSGGYLEHVFRHAAQELFGIHVA-EVTYQPLRNKDFQEVTLEREGQVLLRFAVAYGFRNIQNLVQKLKRGRCP-----------------------------------YHYVEVMACPSGCLNGGGQLK-APDTEGSELLQQLERLYSMVRTEAPEDAPGVQELYQHWLQGEDSERASRLLHTQYHA---VEKPSSGLSIRW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5BK18-1", "uniprot_id": "CIAO3_RAT", "id": "Q5BK18-1", "name": "Cytosolic iron-sulfur assembly component 3", "aln": "MASPFSGALQLTDLDDFIGPSQSCIKPVTVAKKPGSGIAKIHIEDDGSYFQVNPD-GRSQKLEKAK-VSLNDCLACSGCVTSAETILITQQSHEELRKVLDANKVAAPGQ----QRLVVVSVSPQSRASLAARFQLDSTDTARKLTSFFKK-IGVHFVFDTAFARNFSLLESQKEFVQRFREQANS-REALPMLASACPGWICYAEKTHGNFILPYISTARSPQQVMGSLIKDFFAQQQLLTPDKIYHVTVMPCYDKKLEASRPDFFNQEYQTRDVDCVLTTGEVFRLLEEEGVSLSELEPVPLDGLTRSVS-AEEPTSHRGGGSGGYLEHVFRHAAQELFGIHVA-DVTYQPMRNKDFQEVTLEREGQVLLRFAVAYGFRNIQNLVQKLKRGRCP-----------------------------------YHYVEVMACPSGCLNGGGQLK-APDTEGRELLQQVERLYSMVRTEAPEDAPGVQELYQHWLQGEDSERASHLLHTQYHA---VEKINSGLSIRW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H6Q4-1", "uniprot_id": "CIAO3_HUMAN", "id": "Q9H6Q4-1", "name": "Cytosolic iron-sulfur assembly component 3", "aln": "MASPFSGALQLTDLDDFIGPSQECIKPVKVEKRAGSGVAKIRIEDDGSYFQINQD-GGTRRLEKAK-VSLNDCLACSGCITSAETVLITQQSHEELKKVLDANKMAAPSQ----QRLVVVSVSPQSRASLAARFQLNPTDTARKLTSFFKK-IGVHFVFDTAFSRHFSLLESQREFVRRFRGQADC-RQALPLLASACPGWICYAEKTHGSFILPHISTARSPQQVMGSLVKDFFAQQQHLTPDKIYHVTVMPCYDKKLEASRPDFFNQEHQTRDVDCVLTTGEVFRLLEEEGVSLPDLEPAPLDSLCSGAS-AEEPTSHRGGGSGGYLEHVFRHAARELFGIHVA-EVTYKPLRNKDFQEVTLEKEGQVLLHFAMAYGFRNIQNLVQRLKRGRCP-----------------------------------YHYVEVMACPSGCLNGGGQLQ-APDRPSRELLQHVERLYGMVRAEAPEDAPGVQELYTHWLQGTDSECAGRLLHTQYHA---VEKASTGLGIRW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2RRV9-1", "uniprot_id": "NARFL_DANRE", "id": "A2RRV9-1", "name": "Cytosolic Fe-S cluster assembly factor narfl", "aln": "MAVIFR--------------------------------------------------------------------SISGCITSAESVLITQQSHEELYRVLRHNKQVSSTE----QKVVVVSVSPQSRASLAAHYGIGSSEVARKLTSFLKH-LGVHHVFDTAFSRSFSLIESQREFLQRFSQREAD-KKALPMLASACPGWICYAEKTHGEFILPYISTTRSPQQIMGSLVKGYFASQKGVSPQMIYHVTVMPCYDKKLEASRPDFYLSEHETREVDCVITSGEVLKMLEEEKVSLRDVQPAPLDTMFSNVC-GEELLGHAGSGSGGYLHHIYKHAAKQLFGVDVD-ELTYKTMKNKDFQEVTLEKDGQVLLKFAAVYGFRNIQNLVQKLKRGKSP-----------------------------------YHFVEVMACPSGCLNGGGQLKPSADQSNKELLQQVEEVYRSEHPSVPEDDSQVAELYQSWLESVGEEKARQLLHTQYHA---VEKTANGLSIKW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8SYS7-1", "uniprot_id": "NARF_DROME", "id": "Q8SYS7-1", "name": "Probable cytosolic Fe-S cluster assembly factor CG17683", "aln": "-MSRLSRALQLTDIDDFITPSQICIKPVQIDKARSKTGAKIKIKGDGCFEESESG---NLKLNKVD-ISLQDCLACSGCITSAEEVLITQQSREELLKVLQENSKNKASEDWDNVRTIVFTLATQPILSLAYRYQIGVEDAARHLNGYFRS-LGADYVLSTKVADDIALLECRQEFVDRYRENEN-----LTMLSSSCPGWVCYAEKTHGNFLLPYVSTTRSPQQIMGVLVKQILADKMNVPASRIYHVTVMPCYDKKLEASREDFFSKANNSRDVDCVITSVEVEQLLSEAQQPLSQYDLLDLDWPWSNVRPEFMVWAHEKTLSGGYAEHIFKYAAKHIFNEDLKTELEFKQLKNRDFREIILKQNGKTVLKFAIANGFRNIQNLVQKLKREKVSN----------------------------------YHFVEVMACPSGCINGGAQIRPTTGQHVRELTRKLEELYQNLPRSEPENS-LTKHIYNDFLDGFQSDKSYDVLHTRYHD--VVSELSISLNINW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23503-1", "uniprot_id": "NAR1_YEAST", "id": "P23503-1", "name": "Cytosolic Fe-S cluster assembly factor NAR1", "aln": "MSALLSESDLN----DFISPALACVKPTQVSGGKKDNVNMN---------GEYEVSTEPDQLEKVS-ITLSDCLACSGCITSSEEILLSSQSHSVFLKNWG--KLSQQQD-----KFLVVSVSPQCRLSLAQYYGLTLEAADLCLMNFFQKHFQCKYMVGTEMGRIISISKTVEKIIAHKKQKENTGADRKPLLSAVCPGFLIYTEKTK-PQLVPMLLNVKSPQQITGSLIRATFES-LAIARESFYHLSLMPCFDKKLEASRPESLDDG-----IDCVITPREIVTMLQELNLDFKSFLTEDTSLYGRLSPPGWDPRVHWASNLGGTCGGYAYQYVTAVQRLHPGSQMIVLEGRNSDIVEYRLLHDDRIIAAASELSGFRNIQNLVRKLTSGSGSERKRNITALRKRRTGPKANSREMAAATAATADPYHSDYIEVNACPGACMNGGGLLNGEQNSLKR------KQLVQTLNKRHGEELAMVDPLTLGPKLEEAAARPLSLEYVFAPVKQAVEKDLVSVGSTW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ..*:: * ::.*. . : : . . : :*.::..* :* : : . * .::: . ..:..* .. ::: : .::: : . .:::: ***:: *:*:. : . : ..:****: * *:: : :. . .:*: : **:****** : ***:*. *: ::.: . . . * * . : . :: :* *: * * ::.. : : ******.:: :: . . :** :*. .*:.* . . . : * . : :. . . *", "identical_positions": 52, "similar_positions": 122, "identity": "9.9%" }, { "cls_id": "homologset.agr.SGD:S000005185", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q00612-1", "uniprot_id": "G6PD1_MOUSE", "id": "Q00612-1", "name": "Glucose-6-phosphate 1-dehydrogenase X", "aln": "-------------------MAEQVALSRTQVCGILREELYQGDAFHQADTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPEDTFIVGYARSRLTVDD-IRKQSEPFFKATPEER--PKLEEFFARNSYVAGQYDDAASYKHLNSHMNALHQGM---QANRLFYLALPPTVYEAVTKNIQETCMSQTGWNRIIVEKPFGRDLQSSNQLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEG-RGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPATTGSDDVRDEKVKVLKCISEVETDNVVLGQYVGNPNGE-GEAANGYLDDPTVPHGSTTATFAAAVLYVENERWDGVPFILRCGKALNERKAEVRLQFRDVAGDIFH--QQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHKIDR-EKPQPIPYVYGSRGPTEADELMKRVGFQY--EGTYKWVNPHKL-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05370-1", "uniprot_id": "G6PD_RAT", "id": "P05370-1", "name": "Glucose-6-phosphate 1-dehydrogenase", "aln": "-------------------MAEQVALSRTQVCGILREELYQGDAFHQADTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPEDTFIVGYARSRLTVDD-IRKQSEPFFKVTPEER--PKLEEFFARNSYVAGQYDDPASYKHLNSHMNALHQGM---QANRLFYLALPPTVYEAVTKNIQEICMSQTGWNRIIVEKPFGRDLQSSNQLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEG-RGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTDSDDVRDEKVKVLKCISEVETDNVVLGQYVGNPSGE-GEATNGYLDDPTVPHGSTTATFAAAVLYVENERWDGVPFILRCGKALNERKAEVRLQFRDVAGDIFH--QQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHKIDR-EKPQPIPYVYGSRGPTEADELMKRVGFQY--EGTYKWVNPHKL-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97324-1", "uniprot_id": "G6PD2_MOUSE", "id": "P97324-1", "name": "Glucose-6-phosphate 1-dehydrogenase 2", "aln": "-------------------MAEQVTLSRTQVCGILREELYQNDAFHQADTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPKETFIVGYARSQLTVDD-IQKQSEPFFKATPEER--PKLEEFFTRNSYVVGQYDDPASYKHLNSYINALHQGM---QANHLFYLALPPTVYEAVTKNIQETCMSQTGFNRIIVEKPFGRDLQSSNQLSNHISSLFREDQIYRIDHYLDKEMVQNLMVLRFANRIFGPIWNGDNIVCVILTFKEPFGTEG-RGGYFDEFGIIRDVMQSHLLQMLCLVAMEKPATTDSDDVRNEKVKVLKCISEVETDNVILGQYVGNPNGE-GEAANGYLDDPTVPRGSTTATFAAAVLYVKNERWDGVPFILRCGKALNERKAEVRLQFRDIPGDIFH--QKCKRNELVIRMQPNEAVYTTMMTKKPGMFFNPEESELDLTYGNKYKNVKLPGAYERLILDVFCGCQMHFVRTDELREGWRIFTPLLHKIER-EKPQPFPYVYGSRGPTEADELMRRVGFQY--KGTYKGTHKH---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11413-1", "uniprot_id": "G6PD_HUMAN", "id": "P11413-1", "name": "Glucose-6-phosphate 1-dehydrogenase", "aln": "-------------------MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPENTFIVGYARSRLTVAD-IRKQSEPFFKATPEEK--LKLEDFFARNSYVAGQYDDAASYQRLNSHMNALHLGS---QANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEG-RGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQANNVVLGQYVGNPDGE-GEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGKALNERKAEVRLQFHDVAGDIFH--QQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIEL-EKPKPIPYIYGSRGPTEADELMKRVGFQY--EGTYKWVNPHKL-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B959-1", "uniprot_id": "A0A8M2B959_DANRE", "id": "A0A8M2B959-1", "name": "Glucose-6-phosphate 1-dehydrogenase", "aln": "MMGSRASAERAHTTVPTHSDKMSLPLSRSEVFGQLRKELHDDTAFHQSDVHIFIIMGASGDLAKKKIYPTLWWLFRDGLLPEQTYFVGFARSDLTVDA-IRIACMPYMKVVDNEA--ERLAAFFSRNSYISGKYVEESSFSDLNTHLLSLPGGA---EANRLFYLALPPSVYHDVTKNIKHQCMSTKGWNRVIVEKPFGRDLQSSEELSSHLSSLFTEEQIYRIDHYLGKEMVQNLMVLRFGNRIFGPIWNRDSVACVVLTFKEPFGTQG-RGGYFDDFGIIRDVMQNHLLQMLSLVAMEKPASTSSDDVRDEKVKVLKCIEPVTLSDVVLGQYVGDPDGE-GEAKLGYLDDKTVPKGSTQATFATAVLYVKNERWDGVPFILRCGKALNERKAEVRLQFTDVPGDIFS--SQCRRNELVVRVQPNEAIYAKMMSKKPGVYFSPEETELDLTYHSRYRDVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIES-EKTPPIKYKYGSRGPAEADELVQKVGFRY--EGTYKWVNPHKL-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P12646-1", "uniprot_id": "G6PD_DROME", "id": "P12646-1", "name": "Glucose-6-phosphate 1-dehydrogenase", "aln": "---------------MATQKEDHTALDLIIKSLKSPTMVCEGTHFDGKIPHTFVIFGASGDLAKKKIYPTLWWLYRDDLLPKPTKFCGYARSMLTVDS-IKEQCLPYMKVQPHEQ--KKYEEFWALNEYVSGRYDGRTGFELLNQQLEIMENKN---KANRIFYLALPPSVFEEVTVNIKQICMSVCGWNRVIIEKPFGRDDASSQALSDHLAGLFQEDQLYRIDHYLGKEMVQNLMTIRFGNKILSSTWNRENIASVLITFKEPFGTQG-RGGYFDEFGIIRDVMQNHLLQILSLVAMEKPVSCHPDDIRDEKVKVLKSIEALTLDDMVLGQYLGNPQGTNDDARTGYVEDPTVSNDSNTPTYALGVLKINNERWQGVPFILRCGKALNERKAEVRIQYQDVPGDIFE--GNTKRNELVIRVQPGEALYFKMMTKSPGITFDIEETELDLTYEHRYKDSYLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPILHQIEK-EHIRPITYQYGSRGPKEADRKCEENNFKY--SGSYKWHGGKAATSNH---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P11412-1", "uniprot_id": "G6PD_YEAST", "id": "P11412-1", "name": "Glucose-6-phosphate 1-dehydrogenase", "aln": "--------------------------------------MSEGPVKFEKN-TVISVFGASGDLAKKKTFPALFGLFREGYLDPSTKIFGYARSKLSMEEDLKSRVLPHLKKPHGEADDSKVEQFFKMVSYISGNYDTDEGFDELRTQIEKFEKSANVDVPHRLFYLALPPSVFLTVAKQIKSRVYAENGITRVIVEKPFGHDLASARELQKNLGPLFKEEELYRIDHYLGKELVKNLLVLRFGNQFLNASWNRDNIQSVQISFKERFGTEG-RGGYFDSIGIIRDVMQNHLLQIMTLLTMERPVSFDPESIRDEKVKVLKAVAPIDTDDVLLGQYGKSEDGS----KPAYVDDDTVDKDSKCVTFAAMTFNIENERWEGVPIMMRAGKALNESKVEIRLQYKAVASGVFK--DIPN-NELVIRVQPDAAVYLKFNAKTPGLSNATQVTDLNLTYASRYQDFWIPEAYEVLIRDALLGDHSNFVRDDELDISWGIFTPLLKHIERPDGPTPEIYPYGSRGPKGLKEYMQKHKYVMPEKHPYAWPVTKPEDTKDN--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VNW4-1", "uniprot_id": "Q9VNW4_DROME", "id": "Q9VNW4-1", "name": "Glucose-6-phosphate 1-dehydrogenase", "aln": "---------------------------------------MISMDPHNEEAYSIVVFGASGGLAKKKVFPALWALFRENRLPQGTKIFTFTRSPLQTKT-YRLQILPYMELDKHRDP-KKYNLFWTTVHCVQGEYDKPENYVALTEAMVHQETKHNQVRANRIFYLALPPIVFDQVTLNVSRKCSSTTGWNRIIVEKPFARDDISYKAFQTSLCNCFRESQIYLMDHLLSRQVMQNFFALRYSNHLWAETLNHRHVAAVMISIKCELPVSVNRADYFNQFGIIRDLMTNHMIQMLAMLAMDQPYANTADDLRAERLKVLRQVLTPNIGDVVLAQYRNNRRET-DPAKCGYTEHTYIPKDSFTPTFALVVLHINNRRWTGVPFILRAGKALNDTKSEVRIQYKPVDCDTFHSDSTDIRNELVLRSFPTEEVFMRMRLKRQGEDICLRESEINLRVDDR--GPKGLQGLPGYLLNVFQGDQTLFMRSDEQCEIWRIFSPVLATIDS-DRPRPLHYDFGSRGPLLAYRKAERAGFVFFATDEWHQSEETLEYTVKNSKQLIGPHTALKPVRDPRSKRSNSNP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ::****.***** :*::: *:*:. * * : ::** * : *.:: . : *: : *.* .: * : .:::******* *: *: :: : * .*:*:****.:* * :. : * *.::* :** *.:::::*::.:*:.*:: * : .* :::* : .. *..**:.:*****:* .*::*:: :::*::* : .:.:* *::***: : .:::*.** . .* :. : ..* *:* .: ::*.** ***:::*.*****: * *:*:*: : . * ****:* * :: : * * . ::::* : . . : :.: * : *:* ** * **:*:* *: : * * :***** . .. : : ", "identical_positions": 121, "similar_positions": 151, "identity": "20.93%" }, { "cls_id": "homologset.agr.SGD:S000005186", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAF8-1", "uniprot_id": "F1MAF8_RAT", "id": "F1MAF8-1", "name": "", "aln": "---MPWPFSESIKKRACRYLLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAP-LEVTEGFIQSISLSVPWGSLLQDNCALEVRGLEMVFRPRPRGATGSEP-MYWSSFMTSSMQLAKECLSQKLTDEQGEASQ-PFEGLEKFAETIETVLRRVKVTFIDTVLRIEHVPENSKTGAALEIRVDRTVYCDEAADESS---GVDVQQ---PTAFAHKLLQLSGVALFWDEFSASAKSSPVCPTAPVETEPKLSPSWNPKIVYEPHPQLTRTLPEIAPSDPVQIGRLLGRLGLSLTLKQNEVLPGAKLDVDGQIDSFHLFLSPRQVHLLLDMLAAIAGPESSSKIGLANKDRK-NRPMQQEDEYRIQMELNRYYLRKDSLSLGVSSEKSFYETETTRTPSSREEEVFFSMADMDMSHSLSSLPPLGDPPHMDLELSLTSTYTNTPAGSPLSATVLQPTWGEFADHK-EQPVRGPAFQSDLVHPASLQKAALPSRSASVDESRPEFICRLALGIFSVSVLHIDPLSPAETSLTVNPLTRMAIDFFSCIEKMDPAIFSMGDFKAFRAVFAEACSHDHLRFIGTGIKVSYEQRQRS-ASRHFSTDMSIGQMEFLECLFPTDFHSVPPHYTELLTFHSK--EGTDAHLPVCLQLHYKHSETRGPQGNQARLSSVPQKAELQIKLNPVRCELDISIVDRLNSLLQPQKLTTVEMMASHMYASYNKHISLHKAFTEVFLDDSHSPANRRLSVQVATPALHLSVRFPIPDLRSDQE--RGPWFKKSLQKETLHLDFTDLECKTEFVG---------GATPEQTKLELTFRELSGSFQEEKGGPSVKFFHVCGGVDGDTASSDDFDWPRMVLKINPPAMHSILERIAAEEEEENDGHYQEEEEGGAHSLKDVCDLRRPAPSPFSSRRVMFENEQMVMPGDPVEMMEFQDKAISSSHYVLELLLPNVHLTLPNKSFYEKLYNRIFNDLLLWEPTAPSPVETLENVSYGIGLSVASQLINTFSKDSFSPFKSAAPYDE------DSGSEEETLQYFSAVDPNYRSRRKKKLDSQNKNSQSFLSVLLSINHGLMAVFTDVKQDNGDLMENKHGEFWLEFHTGSFFCVTKYEGFDDKHYICLHSSSLRLYHKGIVDGAILPTETRLPCSTRPHWLEPTIYSSEEDGLSRAASDGVGGDN--LNMLSVAVKILSDKSESNTKEFLVAVGLKGATLQHRVLPAGLSWHEQILNFLNIADEPVLGYNPPTSFTTFHVHLWSCALDYRPLHLPIRSLLTVETFSISSSVALDKSSSTLRIIMDEAALHLSDKCNTVAINLNRDYVRVMDMGL---LELTITAVKSDSDGEQTEPRFELHCSSDVVHIRTCSDSCAALMNLIQYVASYGDLHAPHKAEMKPAVPQRKPKVDPSTRSPSRGP---------------VLPEAEQQLLRDLMRDAMEEADLQQASAPVGPQANGVLDEKSHTQEPCCSDLFLFPDESGNASQESSPAYPP-----------LTPHLIGDTVTGATAENDDFCILFAPKAAVQEKEEEPVIKIMVDDAIVIRDDYFSLPITRTDSSKAPLHFPVPAIRYVVKEVSLVWHLYGGKDFATAP-------PTSPAKSYISPHSSPSQT--PTR-HGRHTVCG----------GKGRNHDFLMEIQLSKVKFQHEVYPPCKPECES------SLLEHPVSRQAFIVQDLEIRDRLATSQMNKFLYLYCSKDMPRKAHSNMLTVKALHVRPESGRS-PQECCLRVSLMPLRLNIDQDALFFLKDFFTSLSSEVELLLTPDPEVTKSPGADVTCSLPRHLSTSKEPNLVVSFPGPKQPSPNHSANSAEGSNGLEE-DRSVEETS-FSDQPVFFREFRFTAEVPIRLDYHGKHVSMDQG--TLAGILIGLAQLNCSELKLKRLFYRHGLLGIDKLFSYAITEWLSDIKKNQLPGILGGVGPMHSLVQLVQGLKDLVWLPIEQYRKDGRIVRGFQRGAASFGTSTAMAALELTNRMVQTIQAAAETAYDMVSPST-------------------------------------------------------LSIEPKKAKRFPHHRLAHQPVDLREGVAKAYSVVKEGITDTAQTIYETAAREHESR--GVTGAVGEVLRQIPPAVVKPLIVATEATSNVLGGMRNQIRPDVRQDESQKWRHGED--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80XK6-2", "uniprot_id": "ATG2B_MOUSE", "id": "Q80XK6-2", "name": "Autophagy-related protein 2 homolog B", "aln": "---MPWPFSESIKKRACRYLLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAP-LEVTEGFIQSISLSVPWGSLLQDNCALEVRGLEMVFRPRPRVATGSEP-MYWSSFMTSSMQLAKECLSQKLTDEQGEASQ-PFEGLEKFAETIETVLRRVKVTFIDTVLRIEHVPENSKTGAALEIRVDRTVYCDETADESS---GVNVHQ---PTAFAHKLLQLSGVSLFWDEFSASAKSSPVCSTAPVETEPKLSPSWNPKIVYEPHPQLTRTLPEIAPSDPVQIGRLLGRLELSLTLKQNEVLPGAKLDVDGQIDSFHLFLSPRQVHLLLDMLAAIAGPENSSKIGLANKDRK-NRPMQQEDEYRIQMELNRYYLRKDSLSMGVSSEKSFYETETARTPSSREEEVFFSMADMDMSHSLSSLPPLGDPPHMDLELSLTSTYTNTPAGSPLSATVLQPTWGEFADHK-EQPVRGPAFQSDVVHPASLQKAALSSRSASVDESRPEFICRLALGIFSVSVLHIDPLSPAETSLNVNPLTRMATDFFSCVEKMDPAIFSTGDFKSFRAVFAEACSHDHLRFIGTGIKVSYEQRQRS-ASRHFSTDMSVGQMEFLECLFPTDCHSVPSHYTELLTFHSK--EGTDAHLPVCLQLHYKHSETRGPQGNQARLSSVPQKAELQIKLNPVCCELDISIVDRLNSLLQPQKLTTVEMMASHMYASYNKHISLHKAFTEVFLDDSHSPANRRVSVQVATPALHLSVRFPIPDLRSDQE--RGPWFKKSLQKETLHLEFTDLESKTEFVG---------GSTPEQTKLELTFRELSGSFQEEKGGPSVKFFHVSGGVDGDTASSDDFDWPRMVLKINPPAMHSILERIAAEEEEENDGHYQEEEDGGAHSLKDVCDLRRPAPSPFSSRRVMFENEQMVMPGDPVEMTEFQDKAISNSHYVLELLLPNIHLTLPNKGFYEKLYNRIFNDLLLWEPTAPSPVETLENVSYGIGLSVASQLINTFSKDSFSPFKSAVHYDE------DSGSEEETLQYFSAVDPNYRSRRKKKLDSQNKNSQSFLSVLLSINHGLMAVFTDVKQENGDPMESKHGEFWLEFNSGSFFCVTKYEGFEDKHYICLHSSSLRLYHKGIVDGAILPTETRLPCSTRPHWLEPTIYSSEEDGLSRTASDGVGGDN--LNMLSVAVKILSDKSESNTKEFLVAVGLKGATLQHRVLPAGLSWHEQILNFLNIADEPVLGYNPPTSFTTFHVHLWSCALDYRPLHLPLRSLLTVETFSISSSVALDKSSSTLRIIMDEAALHLSDKCNTVTVNLNRDYVRVMDMGL---LELTITAVKSDSDGEQTAPRFELHCSSDVVHIRTCSDSCAALMNLIQYVASYGDLHGPHKAEMKPGVPQRKPKVDSSARSSSHGP---------------VLPEADQQILRDLMSDAMEEIDLQQASAPVGPQANGVLDEKSHTQEPCCSDLFLFPDESGNVSQESSPAYPS-----------LTHHLISDAVTGVTAENDDFCILFAPKTVVQEKEEEPVIKIMVDDAIVIKDDYFSLPITRTDSSKAPLHFPIPAVRYVVKEVSLVWHLYGGKDFATAP-------PTSPAKSYI-PHSSPSQT--PTR-HGRHTVCG----------GKGRNHDFLMEIQLSKVKFQHEVYPPCKPECES------SLLEHPVSRQVFIVQDLEIRDRLATSQMNKFLYLYCSKDMPRKAHSNMLTIKALHVRPESGRS-PQECCLRVSLMPLRLNIDQDALFFLKDFFTSLSTEVELLLTPDPEVTKSPGADVTCSLPRHLSTSKEPNLVVSFPGPKQASPNHRANSAEGGNGLEE-DVSAEETS-FSDQPVFFREFRFTAEVPIRLDYHGKHVSMDQG--TLAGILIGLAQLNCSELKLKRLFYRHGLLGIDKLFSYAISEWLSDIKKNQLPGILGGVGPMHSLVQLVQGLKDLVWLPIEQYRKDGRIVRGFQRGAASFGTSTAMAALELTNRMVQTIQAAAETAYDMVSPST-------------------------------------------------------LSIEPKKAKRFPHHRLAHQPVDLREGVAKAYSVVKEGITDTAQTIYETAAREHESR--GVTGAVGEVLRQIPPAVVRPLIVATEATSNVLGGMRNQIRPDVRQDESQKWRHGED--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96BY7-1", "uniprot_id": "ATG2B_HUMAN", "id": "Q96BY7-1", "name": "Autophagy-related protein 2 homolog B", "aln": "---MPWPFSESIKKRACRYLLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAP-LEVTEGFIQSISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGSEP-MYWSSFMTSSMQLAKECLSQKLTDEQGEGSQ-PFEGLEKFAETIETVLRRVKVTFIDTVLRIEHVPENSKTGTALEIRIERTVYCDETADESS---GINVHQ---PTAFAHKLLQLSGVSLFWDEFSASAKSSPVCSTAPVETEPKLSPSWNPKIIYEPHPQLTRNLPEIAPSDPVQIGRLIGRLELSLTLKQNEVLPGAKLDVDGQIDSIHLLLSPRQVHLLLDMLAAIAGPENSSKIGLANKDRK-NRPMQQEDEYRIQMELNRYYLRKDSLSVGVSSEQSFYETETARTPSSREEEVFFSMADMDMSHSLSSLPPLGDPPNMDLELSLTSTYTNTPAGSPLSATVLQPTWGEFLDHHKEQPVRGSTFPSNLVHPTPLQKTSLPSRSVSVDESRPELIFRLAVGTFSISVLHIDPLSPPETSQNLNPLTPMAVAFFTCIEKIDPARFSTEDFKSFRAVFAEACSHDHLRFIGTGIKVSYEQRQRS-ASRYFSTDMSIGQMEFLECLFPTDFHSVPPHYTELLTFHSK--EETGSHSPVCLQLHYKHSENRGPQGNQARLSSVPHKAELQIKLNPVCCELDISIVDRLNSLLQPQKLATVEMMASHMYTSYNKHISLHKAFTEVFLDDSHSPANCRISVQVATPALNLSVRFPIPDLRSDQE--RGPWFKKSLQKEILYLAFTDLEFKTEFIG---------GSTPEQIKLELTFRELIGSFQEEKGDPSIKFFHVSSGVDGDTTSSDDFDWPRIVLKINPPAMHSILERIAAEEEEENDGHYQEEEEGGAHSLKDVCDLRRPAPSPFSSRRVMFENEQMVMPGDPVEMTEFQDKAISNSHYVLELTLPNIYVTLPNKSFYEKLYNRIFNDLLLWEPTAPSPVETFENISYGIGLSVASQLINTFNKDSFSAFKSAVHYDE------ESGSEEETLQYFSTVDPNYRSRRKKKLDSQNKNSQSFLSVLLNINHGLIAVFTDVKQDNGDLLENKHGEFWLEFNSGSLFCVTKYEGFDDKHYICLHSSSFSLYHKGIVNGVILPTETRLPSSTRPHWLEPTIYSSEEDGLSKTSSDGVGGDS--LNMLSVAVKILSDKSESNTKEFLIAVGLKGATLQHRMLPSGLSWHEQILYFLNIADEPVLGYNPPTSFTTFHVHLWSCALDYRPLYLPIRSLLTVETFSVSSSVALDKSSSTLRIILDEAALHLSDKCNTVTINLSRDYVRVMDMGL---LELTITAVKSDSDGEQTEPRFELHCSSDVVHIRTCSDSCAALMNLIQYIASYGDLQTPNKADMKPGAFQRRSKVDSSGRSSSRGP---------------VLPEADQQMLRDLMSDAMEEIDMQQGTSSVKPQANGVLDEKSQIQEPCCSDLFLFPDESGNVSQESGPTYAS-----------FSHHFISDAMTGVPTENDDFCILFAPKAAMQEKEEEPVIKIMVDDAIVIRDNYFSLPVNKTDTSKAPLHFPIPVIRYVVKEVSLVWHLYGGKDFGIVP-------PTSPAKSYISPHSSPSHT--PTR-HGRNTVCG----------GKGRNHDFLMEIQLSKVKFQHEVYPPCKPDCDS------SLSEHPVSRQVFIVQDLEIRDRLATSQMNKFLYLYCSKEMPRKAHSNMLTVKALHVCPESGRS-PQECCLRVSLMPLRLNIDQDALFFLKDFFTSLSAEVELQMTPDPEVKKSPGADVTCSLPRHLSTSKEPNLVISFSGPKQPSQNDSANSVEVVNGMEEKNFSAEEAS-FRDQPVFFREFRFTSEVPIRLDYHGKHVSMDQG--TLAGILIGLAQLNCSELKLKRLSYRHGLLGVDKLFSYAITEWLNDIKKNQLPGILGGVGPMHSLVQLVQGLKDLVWLPIEQYRKDGRIVRGFQRGAASFGTSTAMAALELTNRMVQTIQAAAETAYDMVSPGT-------------------------------------------------------LSIEPKKTKRFPHHRLAHQPVDLREGVAKAYSVVKEGITDTAQTIYETAAREHESR--GVTGAVGEVLRQIPPAVVKPLIVATEATSNVLGGMRNQIRPDVRQDESQKWRHGDD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P4T0-1", "uniprot_id": "ATG2A_MOUSE", "id": "Q6P4T0-1", "name": "Autophagy-related protein 2 homolog A", "aln": "MSRWLWPWSNCVKERVCRYLLQHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLETWSVNEFLRSMESP-LELVEGFVSSIEVAVPWAALLTDHCTVCVSGLQLTLQPRQGSGPGAADSQSWASCMTTSLQLAQECLREGLP-EPSEPPQ-PLEGLEMFAQTIETVLRRIKVTFLNTVVRVEHSLGDEDRSVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQ---PPAFLHKLLQLSGVCLYFEELPSQA---------------------------DPPQ------------PPLQIGSCTGYVELMVRLKQNEAFPGPKLEVSGQLGSLHLLLTPRQLQQLQRLLSAVNLADPAGLADKLNK----SRPLGAEDLWLIEQDLN------QQLQAGAVAESLSLYPITNP-LNLDSTDLFFSMAG--LTSSVTSAVSELSVYSVDLGSSVHS---NMAFHRPSTP---------------------------------PHSGGKMAPTPLLDTTRPDSLVKMTLGGVSLTLLQTASPS--------SGPSDLPTHFFAEFDAAKDGPFGSRDFSHLRPRFQRACPCSHVRLTGTAVQLSWELRTGSHSRRTSSTEVHFGQLEVLECLWP--RAATEPEYTEILSFPSH--SGSEASARPCAHLRHTQTIRRVLKSRSRRSTACHCHSELSLDLADFQSDVELGSLDRLAALFRQVTTPSEPPAG--------------------LLTEPPQATELQTVFRLSAPRATLRLRFPIPDLRPD----RDPWAGQAVRAEQLRLELSEPQFRSELNS--------GPGPPAPTRLELTCSDLQGIYEDGEK-PPVPCLRVSKALN-PRSTEAKYFLPQVVVTLNPQSSGTQWETAYEKGRDL------------ELSTESPCELQQPEPSPFSSKRTMYETEEMVIPGDPEEMRTFQSRTLALSRCTLDVIMPSAHIFLPSKEVYESIYNRINNDLLMWEPADLLPTSSAAARPPGSSG--------------FKMCKSAFKLD--------SDSDEEDAQFFSM-ASGVP--QTPAPEPSRRQSQSTFSTLVTVLKGRITALCEAKDETGKRLDVTHGELVLDVEQGTIFSVAQYRGQPGLGYFCLEAEKAKLYHRAAIEDYLLPTHLEVPSFAPPAQLAPTIYPSEE-GVTERGTLGRKGQG--PPMLSAAVRIHLDP-HKNVKEFLVTVRLHKATLRHYMAPPEQSWHSQLLDFLDVLDDPVLGYLPPTVITVLHTHLFSCAVDYRPLYLPVRVLVTAETFTLSSNIVMDTSTFLLRFILDDSALYLSDKCEVESLDLRRDYVCVLDIDL---LELVIKTWKGSTEGRLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYLTSSGDLHPPPRPPSPTEIAG--QKL--SESPASLPS---------------CLPVETALINQRDLTDALLDTERRGLQELAQSSGGP-LPQAS------PVSVYLFPGERSGAQAPLPPPGAS--SHTLG--SKAKEHENEEEGDGDTLDSDEFCILDAPGLGIAPRDGEPIVTQLHPGPIIVHDGHFSQPLGSTDLLRAPAHFPVPSSRVVLREVSFIWHLYGGRDFGLHP-------TYRARVGLTGPRVSPSRSSGPNRPQNSWRTQG----------GIGRQHQVLMEIQLSKVSFQHEVYPEE--SAIAGGLG-QELDERPLSRQVLIVQELEIRDRLATSKINKFLHLHTSERLPRRTHSNMLTIKALHVAPTSSVG-GPECCLRVSMMPLRLNVDQDALFFLKDFFTSLAASINPMVPGDT-----------SEAPR-ETHSRP-------GSPQE----GQSEDTETASNPPEAPGSSHSSS--DQQPIYFREFRFTSEVPICLDYHGKHVTVDQVG-TFMGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLCYALNEWLQDIRKNQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLIRGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPASP------------------------------------------------------VSRSLQDKRSSRKLRRGQQPADLREGMAKAYDAVREGILDTAQTICDVASRGHEQK--GLTGAVGGVIRQLPPTVVKPIIVATEATSNVLGGMRNQILPDAHKDHALKWRLEEAQD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZT64-1", "uniprot_id": "D3ZT64_RAT", "id": "D3ZT64-1", "name": "", "aln": "MSRWLWPWSNCVKERVCRYLLQHYLGHFFQEHLSLDQLSLDLYKGSVVLRDIHLETWSVNEVLRSMESP-LELVEGFVSSIEVAVPWAALLTDHCTVCVSGLQLILQPRQGSGPEAADSQTWASCMTTSLQLAQECLREGLP-EPSEPPQ-PLEGLEMFAQTIETVLRRIKVTFLNTVVRVEHSLGDEERSVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQ---PPAFLHKLLQLTGVCLYFEELPSQV---------------------------DPPK------------PPLQIGSCTGYMELMVKLKQNEAFPGPKLEVSGQLGSLHLLLTPRQLQQLQKLLSAINLADPGGLADKLNK----SRPLGAEDLWLIEQDLN------QQLQAGAVAESLSLHPITSP-LNLDSADLFFSMAG--LTSSVTSGVSELSVYSVDLGSSVHS---NMALHRPSTP---------------------------------THSGGKTAPTPLLDTMRPDSLVKMTLGGLSLTLLQTASPS--------SGSPDLTTHFFAEFDAAKDGPFGSRDFYHLRPRFQRACPCSHVRLTGTAVQLSWELRTGGHSRRTSSTEVHFGQLEVLECLWP--RAASEPEYTEILSFPSY--SGSEASARPCAHLRHTQTFRRVLKSRSRRSTACHCHSELSLDLADFQADVELGSLDRLAVLLRQITTPSEPPAG--------------------LLTEPPQATEQQTVFRLSAPRATLRLRFPIPDLRPE----RDPWAGQAVRTEQLRLELSEPQFRSELNS--------GPGPPAPTRLELTCLDLQGIYEDGEK-PPVPCLRVSKALD-PRSTEAKYFLPQVVVTLNPQSSGTQWETASEKGRDL------------ELSTESPCELQQPEPSPFSSKRTMYETEEMVIPGDPEEMRAFQNRTLALSRCTLDVIMPSAHIFLPSKEVYESIYNRINNDLLMWEPADLLPTSTTAARPPGSSG--------------FKMCKSAFKLD--------SDSDEEDTQFFSM-ASGAP--QTPAPEPSHRQSQSTFSTLVTVLKGRITALCEAKDETGKRLDATHGELVLDVEQGTIFSVAQYRGQPGLGYFCLEAEKATLYHRAAIEDYLLPTHLEVPSFAPPAQLAPTIYPSEE-GVTERGTLGRKSQG--PPMLSAAVRIHLDP-HKNVKEFLVTIRLHKATLRHYMAPPEQSWHSQLLDFLDVLDDPVLGYLPPTVITILHTHLFSCAVDYRPLYLPVRVLITAETFTLSSNIVMDTSTFLLRFILDDSALYLSDKCEVENLDLRRDYVCVLDIDL---LELVIKTWKGSTEGRLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVTSSGDLHPPPQPPSPTEIAG--QKL--SESPASLPS---------------CLPVETALINQRDLTDALLDTERRSLRELAQSSGGP-LPQAS------PVSVYLFPGERSGAQAPLPPPGGP--SHTLGSCSEAKEHDKEEEGDGDTLDSDEFCILDAPGLGIAPRDGEPIVTQLHPGPIVVHDGHFSQPLGSTDLLRAPAHFPVPSSRVVLREVSFIWHLYGGRDFGLHP-------TYRARVGLAGPRVSPSRSSGPNRPQNSWRTQG----------GIGRQHQVLMEIQLSKVSFQHEVYPEE--SAIAGGLD-QELDERPLSRQVLIVQELEIRDRLATSKINKFLHLHTSERLPRRTHSNMLTIKALHVAPTGSVG-GPECCLRVSMMPLRLNVDQDALFFLKDFFTSLAASINPMVPGDT-----------FEAHR-ETHSRP-------SSPQE----GQSEGTETASSPQEAPGSSHSSS--DQQPIYFREFRFTSEVPICLDYHGKHVTVDQVG-TFMGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRKNQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLIRGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPASP------------------------------------------------------ISRSLQDKRSSRKLRRGQQPADLREGMAKAYDAVREGILDTAQTICDVASRGHEQK--GLTGAVGGVIRQLPPTVVKPIIVATEATSNVLGGMRNQILPDAHKDHALKWRLEETQD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2TAZ0-1", "uniprot_id": "ATG2A_HUMAN", "id": "Q2TAZ0-1", "name": "Autophagy-related protein 2 homolog A", "aln": "MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVNEVLESMESP-LELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQSWASCMTTSLQLAQECLRDGLP-EPSEPPQ-PLEGLEMFAQTIETVLRRIKVTFLDTVVRVEHSPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQ---PPAFLHKLLQLAGVRLHYEELPAQE---------------------------EPPE------------PPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQELLSAVSLTDHEGLADKLNK----SRPLGAEDLWLIEQDLN------QQLQAGAVAEPLSPDPLTNPLLNLDNTDLFFSMAG--LTSSVASALSELSLSDVDLASSVRS---DMASRRLSAQ---------------------------------AHPAGKMAPNPLLDTMRPDSLLKMTLGGVTLTLLQTSAPS--------SGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQRACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWP--RGTSEPEYTEILTFPGT--LGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGALDRLAALLRLATVPAEPPAG--------------------LLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPE----PDPWAGQAVRAEQLRLELSEPQFRSELSS--------GPGPPVPTHLELTCSDLHGIYEDGGK-PPVPCLRVSKALD-PKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEEL------------ELSVESPCELREPEPSPFSSKRTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINNDLLMWEPADLLPTPDPAAQPSGFPGPS------GFWHDSFKMCKSAFKLANCFDLTPDSDSDDEDAHFFSVGASGGP--QAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVLDMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPTIYPSEE-GVTERGASGRKGQGRGPHMLSTAVRIHLDP-HKNVKEFLVTLRLHKATLRHYMALPEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFTLSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDL---LELVIKTWKGSTEGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAG--QKL--SESPASLPS---------------CPPVETALINQRDLADALLDTER-SLRELAQPSGGH-LPQAS------PISVYLFPGERSGAPPPSPPVGGP--AGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGEPVVTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGPHP-------GHRARTGLSGPRSSPSRCSGPNRPQNSWRTQG----------GSGRQHHVLMEIQLSKVSFQHEVYPAE--PATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNMLTIKALHVAPTTNLG-GPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGET-----------SAEARPETRAQP-------SSPLE----GQAEGVETTGS-QEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLDYHGKHVTMDQVG-TFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRKNQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPAAP------------------------------------------------------VSRSLQDKRSARRLRRGQQPADLREGVAKAYDTVREGILDTAQTICDVASRGHEQK--GLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQIVPDAHKDHALKWRSDSAQD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IKT5-1", "uniprot_id": "A0A0R4IKT5_DANRE", "id": "A0A0R4IKT5-1", "name": "", "aln": "MSRWLFPWSGSIKKRACRYLLQHYLGHFLEERLSLDQLSLDLYNGSGVIREINLDVWAVNELLDSLGAP-LEIVEGFVNSIAVTIPWAALVTEHCTLEITGLQITCRPKYRTN-GSWDSQGWSSCMTSSMQLAQECLKDPPE-ASEEPPA-PLEGLEMFAQTIETVLRRIKVTFLDTIVRVEHHSLDHETGVALEMRIKRVDYCDEAVRDSSQTVPVDIHQ---PPAFLHKILQLNSVKLLYETLGGSQG---VIHPDDMTSSRETNKSDEDEEVDDAPKSLH---PTQKTPEPLLIGQCSGFIETTVKVKQNEMLPGPKFELDGKVGCLHLLLSPSQITHLTDLLSSLCIETSEGSAGGVVSGGGVSRPLGTDDLRLIEEDLS------KQLNSELYDRDLELDAEPYV-QTLENGEMFYSMGPGCMTSSVLSTRSGSELSDSDMESSIHSQS-SLAQTNPLSPQGMLNCPRRYPVPG-----------SFSSLPQCSRPSKRSSRGSQSEPMKPDSFIRLSLGGVTLTLLEEDPPPGP---DGLSSLAEVSQLFFSELAFFKDSMFSERDFQNLRGSFAKACPHSHIRVTGAAVQLACEMRSAGRHSRATTTDLSFSRLELLECLWD--AGG--PQYTELLQFQSAGVFTMGTTARPCAQFHHSLSEKHMRKSGSRR-RVVRRDSSLRVELGELSSELDLDILGRLEDILQALSHCPSSPQRN------------------KAHNAESHLLEFQSSLLLQSPFAVLKVRFPIPDLRPPGL--RRPQSQRAVRNETLSLQISNLELKSQQGPDVQQDGPRSPGAKLTKLLEACFSDLHGVYEGWDG-EAFPCIRVQKSTD-PQNPDG---IPRIQVQVNEGAGSDSMGVCEGLNRDLG-----------SMSLENPCELREKNSSPFSSNRTMFETEEMVIPADPEEMEEFQSQCICQCQYVVDITFPVAYILLPSKEAFLSIYNRINNDLLMWEPPPPPPSPPPAPPSSFQSSRSPSHHH-RHEEDEFYLCKSAFRLE--------SDSEEEESQFYSASQSKRR--KQLEPQSS--HALSLLCLTVLIGKGRLQAMTDSKNEAGRKVELCHGELILDLEGGKIFSVTQHQNNPNLNFLTIESKRVELYHKAEVPDSPIPVKLEMPRFTSPAHLDPTIYPTEV-GVSSVG--GRETDV---QMLSTAIKVTLDL-ERNVKEFLVALRLHGATLRHHMALTNHSWHEQIVDFLDVIDDDILGYTPPAVITVLHTHLATCAVDYRPLYLPLRVLFTAESFSLSSNIIVDTATFHLRFILDDSALYLSDKCESDTVDLRRDYVCVLDIDL---LELAITTWKGSDSSKLTQPLFELRCSNNVVHVHTCADSCAALVNMLQYLVSLGDLHPPPRHTSPTEIAG--QKLPLSESPASLPS---------------CPPAETAEINQYDLTDALIDTER-ILQEDTQDSGSPSIRRAS------PVSVYLFPDEAPKLRPSVLEGEESDIDGLVSTAMEAHADMMSDEGSECSTDNDDFCILEAPGMGIPPRDGEPVVTVLSQGPIKVRDGYYSWPRGSSDLLRAPTRFPVPQNRVVLREVSVVWHLYGGKDFGGKPSSAHTPHSHKVRTAAPGARGSPSRSAGPSRPQNSWRWVG----------GSGRQHTLLMEIQLTKVSFQHEMYPVVTPSAAGPDTEPAGLVEQPISRQVFIVQELEVRDRLASSQINKFLYLYTSESMPRRAHSNMLTVKALQVMPESGLG-GPECCLRISLLPLRLNIDQDALFFLKDFFSNMAAGVTPYLPVDP-----------AAEVRTDASQKAPDDTDPASALGH----DLAASVETTYSEQSSSSAGSSSS--SDQPIYFREFRFTSEVPIWLDYHGKRVVIEQA--TFAGILIGLAQLNCSELKLKRLCCRHGLLGVDKVIQYAVNEWLTDIRKNQLPGILGGVGPMHSVVQLFHGVRDLFWMPIEQYRKDGRIIRGLQRGAASFGTSTASAALELSNRLVQAIQATAETVYDILSPTPP------------------------------------------------------LTRYITEGRPAPRPRRTPQPADLREGVAKAYDTVREGVIDTAQTLCDVASRGHEQK--GLPGAVGGVLRQIPPTVVRPLIVASEATSNLLGGMRNQIKPDARKEDFLKWRTEDGQE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZX7-1", "uniprot_id": "Q9VZX7_DROME", "id": "Q9VZX7-1", "name": "Autophagy-related protein 2", "aln": "-MSWFNPWDG-LKTKMCRYLLQRYLGQFFENNLNLEQLKVDLYNGKAVVEDIFLKVNAFNDLFEDQGWA-FEVVSGHIGRLTVVVPWNALMTNDSSLEIHNLTITLRPVTRYQSGTTMLESMWSSVSSSMQMAEECMKQVDDDVPFLNHNNALIGLEKFAETIDNVLNRIRAKLTNTTLNIEYILPRSDRKLVLSFQASHVEYKNKTGYEMPMSTSQDTETEEDPNSSFNALPMIAKHNLVIEGLSLHTS--------------------------EVLDVMDHQFGPTPYEQLCKIVELKGAQNIQINIKQTENIVGPKVSLELSLDDIYFMLTPRQIHLLIEFSKGFNCGGQQERPKKGRS--------------------------LKSAPPSEYQMHSLQQPTRMTGILGQNADWCTGMSEADPSEYSVYGNPPRSGYARSRKMSESTNSMVTSCTN-----------------------------------------TLQQELGYTEKSGEILKFKVQISKIYGIALHQDILIQN------TANIDSCSTVFDHASYLRYSDTASGFFLGTLLENHIPLQNQQYLLLRAAPIIVSGSQQRYFQELTSRTTLSATAVDLIEVLDN--------SKEHLLQFDRQRNCPDGYHIRPEIVLTQSSSFMFKQN-------HNRCSNKIECSLDECTAELDISIYDRLGALFGSSPFSGDSASS-----------------------TPYPDDPNQTEFVVKSENLRLHLRFPVVDGRAANDPLKIPWWKKNVRRDFLAVEFRSLVVSS------------------RSQISIVSDELDVFYCDADKQSAVHLLKCQQKMQ-----------PNKKIQIDVLQLKDTSDGQKKARKSP---------------FSSKCTFG--YTSHVEGLDGSVDKTDSLLPGETEEINEFCDSCTQSSKLKIFAFIPHVKVVLESKSMYELIYNRLNGDLFMWEPRSPHYDISPDNEVPESKD--------LYAEPQLEEFRRNLLLST---------SAMESSIYFSMAEPTAS------APPAPPVRNEAFSFELFVEQGTLILFSHLLDPETNQRSKECGKFQVNLKELRLFTVNGLDNDSTRSFFSIQLGEIDALHCGNTLQDLELAWSDLADEK----LLPTIYNFAS--------VHQQQDRKRMEVLSLVAEIKKQP-EQRIKRMKMSFGICGAILQHHSCHSEHSWLNQLIDFMDVADFPIEEYEPFALVSELQLHVWNAGIDYRPKFFPQRAFLDLGYCTLSSNIISSMSGCTLRLLAEDCVLQLG----LVKEESNDSLIPVLNLGL---LNISFRLNAEGSG----QPRVDLRSSIHDMHLKTCYDSAAALAQLIAYVANDRDLCPPEEPILNEDTKPAEPKPNEEHEMSDHTQNHVSKLMADAVIDVESSPNLRAMKSPGGREEGIEIFYFPDEPKEKRKSTSAKLQTKSLMVESPSVIGDILDFESNVILQSYYHQSQVQPQTSLG----SQVQQELGSLGNASLEERDFDIIHDEEISRMDKFGVKQIYIS-EDPLQIVDNHFELPHEKVDLLRPPSNFPVAESTYTLCEMTFTWHLYGGRDFPDEPLK----KSSSSATSGFGMSDTYKYGVSQAQEQDKQDKKGSKKGLLKQPKGSQRNLEVLVEMQLSKIRFSYETYPLT---------------SMYSSRQVLLVSEIEIRDRLRSSDINKFLYHPTGNNLSHKPDENMVIVKALNVRPNPQKSSAEECSLRVSILPIKLNIDQDTLLFLEDFFSGMFRNSASAAGGTKTEGSS------SSATDMPVMSVSKMPEELSDKLPDSEVKEMVERNLNVLIEENSLDVELEEDPATAPPVFFREVIFSPALPICFDYHGRRIELSRG--PVTGLIMGLAQLQGSGINLREIVNRRGILGWNKLCEFLAKEWLKDIKRNQLPNILSGIGPTNAVLQLFQGIYDLFRLPIEQYNKDGRIIRGFQLGAQSFTARTALAALEITSRIIHLLQFTAETTFDMLSAGP--------------------------------------------------------SMKKRKGGRQGKRRRQGRPKDLREGVANAYTIVREGINESANTLIEAAITEHDQK--GYSGAVGAVVRQIPQLVVCPAVLATQATTNILGGAKSSLIPEAKLEARDKWKQEIH--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53855-1", "uniprot_id": "ATG2_YEAST", "id": "P53855-1", "name": "Autophagy-related protein 2", "aln": "---MAFWLPQNIQKRLLLYVLQQIS---LFSNIDLSNLDVSIGSKS------HFSFHDVNLSLDDLNIPNVQINEGIVDELVLKLTVSGGVEIDG----SGLRFIMTP---------------LYSSGSQELHSDFLVKSIQDLTNSMLQ--------FSDPLTTYNR-----YKEDDISSSDSSSDLNSNIEASKPAANGSYTLQNMRNKALNVALAKLK-------------------------------------------------------------------------------IALKDVTIRFIVNDRDP-SDNIVEVHLESIQLITTDANLRHINIENITISSIQKQAVPD-------------------------------------------------SPVHPFNNDDLSQSVYLSKMEATSLYMSAMEEQSNED-----------------------------------------------------------PSEPQVTQEEQENDKCKESLMEINNLNIAFKGLS-----------SVNDLRMSNIVIDIQDVHLAIHKIVEIKNSTLKNIIDIIVTHLDANESFSCQDSQSPSPDKQEPSALSSVDIKCIYLNLG------QDITVILKSFKLEQKENNSLAFSLGSFYSNSSPLTISHKTKPLLTGEQTPQSIALNMGDELDIIISHDGIAHFFKIFQFVSKCMSFYQNK------------------SKGMMPQIASDTKRTVQLTSKAVKLSLKFPY---------------------------------------------------------FLLCFQVSPFIYDSNRELYIELVDVFKKLP-----------------------------------------------------SRCTKILTMSSITISNLQSPLQLG--SYDDTLKEALIYSSVHAIIKEVIFNEEYSGIVQLVEDISAFGKLFTDSKNSECTGKSKS--------------------------------------------------------------------------------KRGSFLQRSVRVLNSSRFVYKQSLSAN---FSLKIDSMKLKVSEIIGPQFGSVEALLSNNFFAITDDSQIVYFTKNLKVERKTPSLLEPQEIMSVVLNKAVN---------------------EPVLYVHRRANGKLKVIFNNIRIHYYARWLEILKKNIGPDNASSKDEPVSQKLSKKQPTSGFP-------WELKCLDCSLILHPFRLKSVMVIVLDNLTTGGSSFIP----QAKLLSKANTLFLIDDYQNFKIQKDKNWPSLINFYAGQGFSAIGKIDTLNFLINKSDGALLLDCKIEQVGLSLCADSFQTFCQLCIDLKYPQTFPDEEKFRTQLKNPIDVFKDIDCDLFN--------------------SAFIRENNHQNDYDSVHLVDSFLDKTHEFNNGARSKLSSQG---------SYEMDSSSGTATGGILLPHES-------------YLDSAQPKEEDTPPIASKEQERDVDIRGSIDVEKVVIKLFDGYDWKYTRKFIANTVEKLDKELSKAEASSSKSNVPQSEANIFDSIYISANKNNVT---------DLRRNLDGEIQGVQNSFSDVSKVNLR-----------------PSKHYKALIQLNKVHVNLKNYRVDEPDESN-----SDNSTDVLNRCVVSIYEFEIIDNVPTSTWNKFVTLLKHEPWPHS--SPMFLLDLEFIRPIDFLQ-AVELVMQLNVAPLRLHVDQDTLEFLIRFLGFKDKRFELID--------------------------------------------------------------------EYPDIVFIQKFSTNSIKLRLDYKPKKVDYAGLRSGQTSELMNFFTLDGSKIILKSVVLY-GLNGFDELNNKLKAIWTPDITKKQLPGVLEGLAPVRSFMAIGSGVKTLVTVLMSEYRQEGHLGRSLKKGGNVFLKTTTGDFVKLGVKLTSGTQAILENTEELFGGVGSNGRVYDASKFGSADGADSDTAAVLDLDTLFEEDQLVGSKYSRIRDHEPTAVVIDMSSPGDHNEPTIVSLYADQPLDLPTGLKEAYSSLEKHMHIAYDAVWRAKGQMKDDKRGGPSAAAVYVARAAPVAIIRPLIGATEAVSKTLQGIANQVDKTHNEQINDKYKSNRTDS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : *:*:: : ..:.*.:*.:.: . . :. .* : . . .:: .* : : : :. . : . .* : * : * :: .: : . *::.: . . : : . . . . * : : . . : . .: .. : : : :: : :: : . . : .: . . . : : : . : . . : : . : :. : : * . : :. . :: :: : . : : * ::** :: . . . : . ... : * : . . . . : . : ::. .. :. . : : : :. . . . ..: :.. . :: : . . * :: :* . . : *:: * .: : . : . : ..: :* : .. : ... ::: . .* * : . :::. :. . . * .. . : : * ** : :: : : . * . . : . : . . . : . . * . . . . * .. :* . : . . . . :**.*: .. : * .* .. : ::*: *.: :* ***: : .: . *. :. : * * :::.: *::*::***:* ** *: : * : : : : :**: ::: . ::.: *: * : *: : *: * ::: * ** ::***.:* *:.* .:.: : *. *. : :.:*.::*:: *.:: *. * *: ::: :: * *.. ::.. : . :* ** *: :** :.: : : ::: . ::.: * ..*. * * * :: * : *::*.:. * * ..: . : *:: ", "identical_positions": 98, "similar_positions": 371, "identity": "4.39%" }, { "cls_id": "homologset.agr.SGD:S000005187", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LML7-1", "uniprot_id": "F1LML7_RAT", "id": "F1LML7-1", "name": "Huntingtin-interacting protein 1-related protein", "aln": "----MNSIKNVP---ARVLSRR-PGHSLEAE-REQFDKTQAISISKAINSQEAPVKEKHARRIILGTHHEKGAFTFWSYAIGLPLPSSSILSWKFCHVLHKVLRDGHPNVLHDCQRYRSNIREIGDLWGHLRDQYGHLVNIYTKLLLTKISFHLKHPQFPAGLEVTDEVLEKAAGTDVNNIFQLTVEMFDYMDCELKLSESVFRQLNTAIAVSQMSSGQCRLAPLIQVIQDCSHLYHYTVKLMFKLHSCLPADT----LQGHRDRFHEQFHSLRNFFRRASDMLYFKRLIQIPRLPEGPPNFLRASALAEHIKPVVVIPEEAPEEEEPENLIEISSGPPAGEPVQVVADLFDQTFGP-----------PNGSMKDDRDLQIENLKREVETLRAELEKIKMEAQRYISQLKGQVNSLEAELEEQRKQKQKALVDNEQLRHELAQLKALQLEGARNQGLREEAERKASATEARYSKLKEKHNELINTHAELLRKNADTAKQLTVTQQSQEEVARVKEQLAFQMEQVKRESEMKMEEQSDQLEKLKRELVAKAGELAHAQEALSRTEQSGSELSSRLDTLNAEKEALSGAIRQREAELLAAQSLVREKEEALSQEQQRSAQEKGELQGRLAEKESQEQGLQQKLLDEQFAVLRGAAAEAEAILQDAVSKLDDP-LHLRCTSSPDYLVSRAQAALDSVSGLEKGHTQYLAS---SEDASALVAALTRFSHLAADTIVNGGATSHLAPT-DPADRLIDTCRECGARALELMGQLQDQTKLPRAQPSLMRAPLQGILQLGQDLKPKSLDVRQEELGAMVDKEMAATSAAIEDAVRRIEDMMNQARHESSGVKLEVNERILNSCTDLMKAIRLLVMTSTSLQKEIVESGRGAATQQEFYAKNSRWTEGLISASKAVGWGATQLVESADKVVLHMGK----YEELIVCSHEIAASTAQLVAASKVKANKNSPHLSRLQECSRTVNERAANVVASTKSGQEQIEDRGELSDTMDFSGLSLIKLKKQEMETQVRVLELEKTLEAERVRLGELRKQHYVLAGGMGTPGEEEPSRPSPAPRSGATKKPPLAQKPSIAPRPDNQLDKKDGVYPAQLVNY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKY5-1", "uniprot_id": "HIP1R_MOUSE", "id": "Q9JKY5-1", "name": "Huntingtin-interacting protein 1-related protein", "aln": "----MNSIKNVP---ARVLSRR-PGHSLEAE-REQFDKTQAISISKAINSQEAPVKEKHARRIILGTHHEKGAFTFWSYAIGLPLSSSSILSWKFCHVLHKVLRDGHPNVLHDYQRYRSNIREIGDLWGHLRDQYGHLVNIYTKLLLTKISFHLKHPQFPAGLEVTDEVLEKAAGTDVNNIFQLTVEMFDYMDCELKLSESVFRQLNTAIAVSQMSSGQCRLAPLIQVIQDCSHLYHYTVKLMFKLHSCLPADT----LQGHRDRFHEQFHSLKNFFRRASDMLYFKRLIQIPRLPEGPPNFLRASALAEHIKPVVVIPEEAPEEEEPENLIEISSAPPAGEPV-VVADLFDQTFGP-----------PNGSMKDDRDLQIENLKREVETLRAELEKIKMEAQRYISQLKGQVNGLEAELEEQRKQKQKALVDNEQLRHELAQLKALQLEGARNQGLREEAERKASATEARYSKLKEKHSELINTHAELLRKNADTAKQLTVTQQSQEEVARVKEQLAFQMEQAKRESEMKMEEQSDQLEKLKRELAARAGELARAQEALSRTEQSGSELSSRLDTLNAEKEALSGVVRQREAELLAAQSLVREKEEALSQEQQRSSQEKGELRGQLAEKESQEQGLRQKLLDEQLAVLRSAAAEAEAILQDAVSKLDDP-LHLRCTSSPDYLVSRAQAALDSVSGLEQGHTQYLAS---SEDASALVAALTRFSHLAADTIVNGAATSHLAPT-DPADRLMDTCRECGARALELVGQLQDQTVLPRAQPSLMRAPLQGILQLGQDLKPKSLDVRQEELGAMVDKEMAATSAAIEDAVRRIEDMMSQARHESSGVKLEVNERILNSCTDLMKAIRLLVMTSTSLQKEIVESGRGAATQQEFYAKNSRWTEGLISASKAVGWGATQLVESADKVVLHMGK----YEELIVCSHEIAASTAQLVAASKVKANKNSPHLSRLQECSRTVNERAANVVASTKSGQEQIEDR----DTMDFSGLSLIKLKKQEMETQVRVLELEKTLEAERVRLGELRKQHYVLAGGMGTPSEEEPSRPSPAPRSGATKKPPLAQKPSIAPRTDNQLDKKDGVYPAQLVNY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75146-1", "uniprot_id": "HIP1R_HUMAN", "id": "O75146-1", "name": "Huntingtin-interacting protein 1-related protein", "aln": "----MNSIKNVP---ARVLSRR-PGHSLEAE-REQFDKTQAISISKAINTQEAPVKEKHARRIILGTHHEKGAFTFWSYAIGLPLPSSSILSWKFCHVLHKVLRDGHPNVLHDCQRYRSNIREIGDLWGHLHDRYGQLVNVYTKLLLTKISFHLKHPQFPAGLEVTDEVLEKAAGTDVNNIFQLTVEMFDYMDCELKLSESVFRQLNTAIAVSQMSSGQCRLAPLIQVIQDCSHLYHYTVKLLFKLHSCLPADT----LQGHRDRFHEQFHSLRNFFRRASDMLYFKRLIQIPRLPEGPPNFLRASALAEHIKPVVVIPEEAPEDEEPENLIEISTGPPAGEPV-VVADLFDQTFGP-----------PNGSVKDDRDLQIESLKREVEMLRSELEKIKLEAQRYIAQLKSQVNALEGELEEQRKQKQKALVDNEQLRHELAQLRAAQLEGERSQGLREEAERKASATEARYNKLKEKHSELVHVHAELLRKNADTAKQLTVTQQSQEEVARVKEQLAFQVEQVKRESELKLEEKSDQLEKLKRELEAKAGELARAQEALSHTEQSKSELSSRLDTLSAEKDALSGAVRQREADLLAAQSLVRETEAALSREQQRSSQEQGELQGRLAERESQEQGLRQRLLDEQFAVLRGAAAEAAGILQDAVSKLDDP-LHLRCTSSPDYLVSRAQEALDAVSTLEEGHAQYLTS---LADASALVAALTRFSHLAADTIINGGATSHLAPT-DPADRLIDTCRECGARALELMGQLQDQQALRHMQASLVRTPLQGILQLGQELKPKSLDVRQEELGAVVDKEMAATSAAIEDAVRRIEDMMNQARHASSGVKLEVNERILNSCTDLMKAIRLLVTTSTSLQKEIVESGRGAATQQEFYAKNSRWTEGLISASKAVGWGATQLVEAADKVVLHTGK----YEELIVCSHEIAASTAQLVAASKVKANKHSPHLSRLQECSRTVNERAANVVASTKSGQEQIEDR----DTMDFSGLSLIKLKKQEMETQVRVLELEKTLEAERMRLGELRKQHYVLAGASGSPGEEVAIRPSTAPRSVTTKKPPLAQKPSVAPRQDHQLDKKDGIYPAQLVNY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VD75-1", "uniprot_id": "HIP1_MOUSE", "id": "Q8VD75-1", "name": "Huntingtin-interacting protein 1", "aln": "MDRMASSMKQVSNPLPKVLSRRGVGAGMEAAERESFERTQTVSVNKAINTQEVAVKEKHARTCILGTHHEKGAQTFWSVVNRLPLSSNAMLCWKFCHVFHKLLRDGHPNVLKDSLRYKNELSDMSRMWGHLSEGYGQLCSIYLKLLRTRMEYHTKNPRFPGNLQMSDRQLDEAGESDVNNFFQLTVEMFDYLECELNLFQTVFNSLDMSRSVSVTTAGQCRLAPLIQVILDCSHLYDYTVKLLFKLHSCLPADT----LQGHRDRFMEQFTKLKDLFQRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHISPVVVIPAEVSSPDSEPVLEKDDLMDMDASQQTLFDNKFDDVFGSSLSSDPFNFNNQNGVNKDEKDHLIERLYREISGLTGQLDNMKIESQRAMLQLKGRVSELEAELAEQQHLGRQAMDDCEFLRTELDELKRQREDTEKAQRSLTEIERKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQVSVARQAQVDLEREKKELADSFAR--------TQEQQDVLENLKHELATSRQELQVLHSNLETSAQSEAKWLTQIAELEKEQGSLATVAAQREEELSALRDQLESTQIKLAG---------------------AQESMCQQVKDQRKTLLAGIRKAAEREIQEALSQLEEP-TLISCAGSTDHLLSKVSSVSSCLEQLEKNGSQYLAC---PEDISELLHSITLLAHLTGDTIIQGSATSLRAPP-EPADSLTEACRQYGRETLAYLSSLEEEGTMENADVTALRNCLSRVKTLGEELLPRGLDIKQEELGDLVDKEMAATSAAIEAATTRIEEILSKSRAGDTGVKLEVNERILGSCTSLMQAIKVLVVASKDLQKEIVESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATIMVDAADLVVQGKGK----FEELMVCSREIAASTAQLVAASKVKANKGSLNLTQLQQASRGVNQATAAVVASTISGKSQIEET----DSMDFSSMTLTQIKRQEMDSQVRVLELENDLQKERQKLGELRKKHYELAGVAEGWEEGTEASPSTVQEAIPDKE-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GA90-1", "uniprot_id": "A0A8I6GA90_RAT", "id": "A0A8I6GA90-1", "name": "Huntingtin-interacting protein 1", "aln": "MDRMASSMKQVPNPLPKVLSRRGVGAGMEAAERESFERTQTVSVNKAINTQEVAVKEKHARTCILGTHHEKGAQTFWSVVNRLPLSSNAMLCWKFCHVFHKLLRDGHPNVLKDSLRYKNELSDMSRMWGHLSEGYGQLCSIYLKLLRTRMEYHTKNPRFPGNLQMSDRQLDEAGESDVNNFFQLTVEMFDYLECELNLFQTVFNSLDMSRSVSVTTAGQCRLAPLIQVILDCSHLYDYTVKLLFKLHSCLPADT----LQGHRDRFMEQFTKLKDLFQRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHISPVVVIPAEVSSPDSEPVLEKDDLMDMDASQQSLFDNKFDDIFGSSLSSDPFNFNNQNGVNKDEKDHLIERLYREISGLTGQLDNVKIESQRAMLQLKGRVSELEAELAEQQHLGRQATDDCEFLRTELDELKRQREDTEKAQRSLTEIEKKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQVSVARQAQVDLEREKKELADSFARVSEQTQRKTQEQQDVLETLKHELATSRQELQVLHGNLETSAQSEAKWLTQIAELEKEQGSLATAAAQREEEFSALRDQLESTQLKLAG---------------------AQDSMCQQIKDQRRILLAGARKAAELEIQEALGQLEEPALLISCAGATDHLLSKVNSVSSCLEQLEKSRSQYLAC---PEEISELLHSITLLGHLTSDTIIQGTATSLRAPP-ESADSLTEACRQYGRETLAYLSSLEEEGAMEKADTTAIANCLGKIKTIGEELLPRGLDIKQEELGDLVDKEMAATSAAIEAATTRIEEILSKSRAGDTGVKLEVNERILGSCTSLMQAIKVLVVASKDLQKEIVESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATIMVDAADLVVQGKGK----FEELMVCSHEIAASTAQLVAASKVKANKGSLNLTQLQQASRGVNQATAAVVASTISGKSQIEET----DSMDFSSMTLTQIKRQEMDSQVRVLELENDLQKERQKLGELRKKHYELAGVAEGWEEGTEASPSAVQEAVPDKE-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00291-1", "uniprot_id": "HIP1_HUMAN", "id": "O00291-1", "name": "Huntingtin-interacting protein 1", "aln": "MDRMASSMKQVPNPLPKVLSRRGVGAGLEAAERESFERTQTVSINKAINTQEVAVKEKHARTCILGTHHEKGAQTFWSVVNRLPLSSNAVLCWKFCHVFHKLLRDGHPNVLKDSLRYRNELSDMSRMWGHLSEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDVNNFFQLTVEMFDYLECELNLFQTVFNSLDMSRSVSVTAAGQCRLAPLIQVILDCSHLYDYTVKLLFKLHSCLPADT----LQGHRDRFMEQFTKLKDLFYRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHISPVVVIPAEASSPDSEPVLEKDDLMDMDASQQNLFDNKFDDIFGSSFSSDPFNFNSQNGVNKDEKDHLIERLYREISGLKAQLENMKTESQRVVLQLKGHVSELEADLAEQQHLRQQAADDCEFLRAELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQLEVLESLKQELATSQRELQVLQGSLETSAQSEANWAAEFAELEKERDSLVSGAAHREEELSALRKELQDTQLKLAS---------------------TEESMCQLAKDQRKMLLVGSRKAAEQVIQDALNQLEEP-PLISCAGSADHLLSTVTSISSCIEQLEKSWSQYLAC---PEDISGLLHSITLLAHLTSDAIAHGATTCLRAPP-EPADSLTEACKQYGRETLAYLASLEEEGSLENADSTAMRNCLSKIKAIGEELLPRGLDIKQEELGDLVDKEMAATSAAIETATARIEEMLSKSRAGDTGVKLEVNERILGCCTSLMQAIQVLIVASKDLQREIVESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATVMVDAADLVVQGRGK----FEELMVCSHEIAASTAQLVAASKVKADKDSPNLAQLQQASRGVNQATAGVVASTISGKSQIEET----DNMDFSSMTLTQIKRQEMDSQVRVLELENELQKERQKLGELRKKHYELAGVAEGWEEGTEASPPTLQEVVTEKE-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33338-1", "uniprot_id": "SLA2_YEAST", "id": "P33338-1", "name": "Protein SLA2", "aln": "--------------------------------MSRIDSDLQKALKKACSVEETAPKRKHVRACIVYTWDHQSSKAVFTTLKTLPLANDEVQLFKMLIVLHKIIQEGHPSALAEAIRDRDWIRSLGRVHSGGSS-YSKLIREYVRYLVLKLDFHAHHRGFNNGTFEYEEYVSLVSVSDPDEGYETILDLMSLQDSLDEFSQIIFASIQSER-----RNTECKISALIPLIAESYGIYKFITSMLRAMHRQLNDAEGDAALQPLKERYELQHARLFEFYADCSSVKYLTTLVTIPKLPVDAPDVFLINDVDESKEIKFKKREPSVTPARTPARTPTPTPPVVAEPAISPRPVSQRTTST-----------PTGYLQTMPTGATTGMMIPTATGAANAIFPQATAQMQPDFWANQQAQFANEQNRLEQERVQQLQQ-QQAQQELFQQQLQKAQQDMMNMQLQQQNQHQNDLIALTNQYEKDQALLQQYDQRVQQLESEITTMDSTASKQLANKDEQLTALQDQLDVWER----KYESLAKLYSQLRQEHLNLLPRFKKLQLKVNSAQESIQKKEQLEHKLKQKDLQMAELVKDRDRARLELERSINNAEADSAA---------------------ATAAAETMTQDKMNPILDAILESGINTIQESVYNLDSPLSWSGPLTPPTFLLSLLESTSENATEFATSFNNLIVDGLAHGDQTEVIHCVSDFSTSMATLVTNSKAYAVTTLPQEQSDQILTLVKRCAREAQYFFEDLMSENLNQVGDEEKTDIVINANVDMQEKLQELSLAIEP------LLNIQSVKSNKETNPHSELVATADKIVKSSEHLRVDVPKPLLSLALMIIDAVVALVKAAIQCQNEIATT--TSIPLNQFYLKNSRWTEGLISAAKAVAGATNVLITTASKLITSEDNENTSPEQFIVASKEVAASTIQLVAASRVKTSIHSKAQDKLEHCSKDVTDACRSLGNHVMGMIEDDHSTSQQQQPLDFT--SEHTLKTAEMEQQVEILKLEQSLSNARKRLGEIRRHAYYNQDDD-----------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: ::.** . :*.. *.**.* *: * ..:.: :.:: ***... : :*: *:**::::***..* : * :. : .:. : . . *.:* * : * ::.:* :: * . :. :. .. :* :: :: ::::. :. :: : :* .:: :*:::.** :* :. :*.: ..:: :* * ** ::*: *. * ::: .*.: *:. *: **:** ..*:.: . : * . . .. : .. .* : : .: : :* .: : : . .: : : : : ** : : : : : : ::: . .: ::. * : . : : ::: :. : : : : . * .. :. . . *::* .: : :. : :* : *. : : .*: . :.. : : . *: :* . . :*::: :*:.* .. .*:* . : . : :. : : :: .:: :. . : :. : . : . : :* : :. . .: . .* .: : : : :.* .* :. : : :..* . .: .: . ::::* : :*. . ::.*: *: :: . *.**. : : . ::** ************:***. .:. :: :*. :: .: *:::*.*:*:**** ******:**:. * :*:..*: *.: : . . .: .. : :**: : :* **: **.:*:**: *. * :***:*:: * . ", "identical_positions": 135, "similar_positions": 343, "identity": "12.21%" }, { "cls_id": "homologset.agr.SGD:S000005188", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48024-1", "uniprot_id": "EIF1_MOUSE", "id": "P48024-1", "name": "Eukaryotic translation initiation factor 1", "aln": "-------------------------------------------------------------------------------MSAIQNLHSFDPFADASKG-DDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLI-EIGLAKDDQLKVHGF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41567-1", "uniprot_id": "EIF1_HUMAN", "id": "P41567-1", "name": "Eukaryotic translation initiation factor 1", "aln": "-------------------------------------------------------------------------------MSAIQNLHSFDPFADASKG-DDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLV-EIGLAKDDQLKVHGF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0KVZ2-1", "uniprot_id": "A0ABK0KVZ2_RAT", "id": "A0ABK0KVZ2-1", "name": "", "aln": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKG-DDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLI-EIGLAKDDQLKVHGF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CXU9-1", "uniprot_id": "EIF1B_MOUSE", "id": "Q9CXU9-1", "name": "Eukaryotic translation initiation factor 1b", "aln": "-------------------------------------------------------------------------------MSTIQNLQSFDPFADATKG-DDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLL-EVGIVKEEQLKVHGF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60739-1", "uniprot_id": "EIF1B_HUMAN", "id": "O60739-1", "name": "Eukaryotic translation initiation factor 1b", "aln": "-------------------------------------------------------------------------------MSTIQNLQSFDPFADATKG-DDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLL-EVGIVKEEQLKVHGF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZS3-1", "uniprot_id": "ETIF1_DROME", "id": "Q9VZS3-1", "name": "Eukaryotic translation initiation factor eIF1", "aln": "-------------------------------------------------------------------------------MS-IQNLNTRDPFADAIKGNDDDIQDG---LVHIRIQQRNGRKTLTTVQGLSAEYDLKKIVRSCKKEFACNGTVIEHPEYGEVLQLQGDQRENICQWLT-KVGLAKPDQLKVHGF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32911-1", "uniprot_id": "SUI1_YEAST", "id": "P32911-1", "name": "Eukaryotic translation initiation factor eIF-1", "aln": "-------------------------------------------------------------------------------MS-IENLKSFDPFADTGDD-----ETATSNYIHIRIQQRNGRKTLTTVQGVPEEYDLKRILKVLKKDFACNGNIVKDPEMGEIIQLQGDQRAKVCEFMISQLGLQKKN-IKIHGF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* *****: .. . :******************:. :** *:::: **.*****.:::.** **::******* ::*::: ::*: * : :*:***", "identical_positions": 52, "similar_positions": 33, "identity": "26.8%" }, { "cls_id": "homologset.agr.SGD:S000005189", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V6I3-1", "uniprot_id": "G3V6I3_RAT", "id": "G3V6I3-1", "name": "", "aln": "MGGGDLNLKKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQR-YAEDVGAVKKK-----EEKLDWMYQGPGGMVSRDEYLLG-RPIDKYVFEKMEEREAGCSSETGLLPGS-------------IFAPSGANSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKMRKIKELLQMSLE-------KKEKKKKKEKKKKHRKHKHRSSSSDRSSSEDEQSHGRSQKKMANSFPVLSKVPG-----------------------YGLQVRDSDRNQGLQGSLGEQR----AVKNHSRS-----------------------SSSPARHASRKSTKEERSRDRRSRSPG------RKSLSPRPSKQ-HTSKANRKER---DSPSPKKEVYQRRHASGYTR--------------------KLSAEELERKRQEMMENAKWREEERLNTLKRHAKEDEQEHRLERLDSRSGKFIHR-MKLESASTSSLEDRVKRNIHSLQRTSMALEKNFMRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBF7-1", "uniprot_id": "CWC25_MOUSE", "id": "Q9DBF7-1", "name": "Pre-mRNA-splicing factor CWC25 homolog", "aln": "MGGGDLNLKKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQR-YAEDVGAVKKK-----EEKLDWMYQGPGGMVNRDEYLLG-RPIDKYVFEKMEEREAGCSSETGLLPGS-------------IFAPSGANSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLE-------KKEKKKKKEKKKKHRKHKHRSSSSGGSSSEDEQSQARSQKKMANSFPVLSKVPG-----------------------YGLQVRDSDRNRGLQGSLGEQR----AIKNNSRSR----------------------SSSPPRHASKKSTKEERPRDRRSRSPS------RRSRSPRPSKP-HTSKVNRKER---DSPSPKKEAYQRRHASGYTR--------------------KLSAEELERKRQEMMENAKWREEERLNTLKRHAREDEREHRLERLDSRSGKFLHR-MKLESASTSSLEDRVKRNIHSLQRTSVALEKNFMRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NXE8-1", "uniprot_id": "CWC25_HUMAN", "id": "Q9NXE8-1", "name": "Pre-mRNA-splicing factor CWC25 homolog", "aln": "MGGGDLNLKKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQR-YAEDVGAVKKK-----EEKLDWMYQGPGGMVNRDEYLLG-RPIDKYVFEKMEEKEAGCSSETGLLPGS-------------IFAPSGANSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLE-------KKEKKKKKEKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPG-----------------------YGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSS--------------------SHSPPRHASKKSTREAGSRDRRSRSLG------RRSRSPRPSKL-HNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTR--------------------KLSAEELERKRQEMMENAKWREEERLNILKRHAKDEEREQRLEKLDSRDGKFIHR-MKLESASTSSLEDRVKRNIYSLQRTSVALEKNFMKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQF5-1", "uniprot_id": "Q9VQF5_DROME", "id": "Q9VQF5-1", "name": "", "aln": "MGGGDLNLKKSWHPHTMKNQERVWKAEEQAKMEERKLQDLRKEINEERDREELRR-LGESSGVLSNNGGAAGEAKLEWMYKNSTELINREEYLLG-RKIDKSFETLQAEESRQEQNTVGLKQTINHVEHDCVPFSIRTYRNVQSNEQVDIQRKTLEDPLMLIKQREMESRRKLLENPVKLKEIHRILKTEQEQKAAEGKKKNKKNKKSKKSKKKKKNRRSSNEESSDSESNDSDDDLDRKLARQVSKLKGDQGDLKLDKLLDAKYRTISNQLDMATKKKKSKKSKKKKSSDSSDESSDEEEEPRRKHKRSHSSEDRNQRERRRSRSPRDRKKRQSRSPEQRQRQRSPEERRERRRSRSRSPLARRQRRTRSPEDRKARRQSKDTSKQREKRRSRTPEERSRSKRSRSRSSKGDDKRRIAERPPPSRPTGKPKLSEADREARLREMMDNATWREADRSQVVRKHREAYAREEAQNRERDFDKEFINKEVKKAIANHNSIGDRIRANLNNIQRTASSMDSNFARK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53854-1", "uniprot_id": "CWC25_YEAST", "id": "P53854-1", "name": "Pre-mRNA-splicing factor CWC25", "aln": "MGSGDLNLLKSWNPKLMKNRKKVWETEQDLITEQQKLNTRLKEIEKERELNELLNESSKDKPETLKNDLALKKSGLEWMYQDAKLSDEKEDYLLGKKKLDSSILNQPATPPVRAATTISASGAA--------------------------------------------------------TSIS---------------SQKKKSKLLKDDPMSKFKVTKQQRRTPDSTKKRAMSQRGKPLSKPAPDLDY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.***** ***:*: ::* ::**::*:. *.:*:: :*:.:** :*: . .:. :: : *:***:.. .:::**** : :*. . . . .* .::**.* *.. * : ... ..* .: : : ::. . *. ", "identical_positions": 38, "similar_positions": 64, "identity": "7.27%" }, { "cls_id": "homologset.agr.SGD:S000005190", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TQI8-1", "uniprot_id": "TSYL2_MOUSE", "id": "Q7TQI8-1", "name": "Testis-specific Y-encoded-like protein 2", "aln": "MDRPDEGPPAKTPRLSSSEPRQRDLPPPPPPPLQRLPLPPPQQRPRPQEETEAAQVLADMRGVGPTLPPPLPYVILEEGGIRAYFTLSAESPGWDHAMESGFGEAPSTGIMETLPSSEISGGSLAIDFQVAE------------PSSLGEKALETCSLGGWGPQMLVGPKRKEEAIIIVEDEDEDDKESVR-----RRQRRRRRR------------------------RKQRKAKESRERSAQRMESILQALESIQMDLEAVNIKAGKAFLRLKRKFIQMRRPFLERRDLIIQHIPGFWVKAFLNHPRISILINQRDRDIFRYLTNLQVQDLRHI-----SMGYKMKLYFQ-TNPYFTNMVIVKEFQRN------RSGRLVSHSTPIRWHRGQ---------EPQAYNRRSHD--TRESFFNWF------SNHSLPEADRIAEIIKNDLWVNPVRYYMRRGGYRSSRKKQHGKE-RAKNQYEMVIMEDAHDHYAIEDILSDISEIDEITDNETIHDIKISDFMETTDYFETTDNEVTDANENLCDSENPDHSEGYNTKITDNKGSVAANPDDNSDDPEEKNTYDSEDSNSEKADGDNTTLR-DNQQVTNIQDSSDSDNGDEGSDDEDDDGNEGDNEGSDDDDDDNEGSDDDDRDIRYYKNGPEVFDKALDNRTNQNDYEEEVELISEDSVEEEEE-TSEEASQLSEDSYEDERIYGEERSEVNSEDSDIQEVLPVPKAWASLGKKGKIG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A096MJ32-1", "uniprot_id": "A0A096MJ32_RAT", "id": "A0A096MJ32-1", "name": "Testis-specific Y-encoded-like protein 2", "aln": "MDRPDEGPPAKTPRLSSSESRQRDLPPPPPPPLLRLPLPPPQQRPRPQEETEAAQVLADMRGVGPTLPPPLPYVILEEGGIRAYFTLGAESPGWDPAIESGFGEVPSTEIIETLPSSEASRGSLEIDFQVAE------------HSSLGEKALETCSFGGWGPQMLVGPKRKEEAIIIVEDEDEDEKESMRRLQQRRRRRRRRRR------------------------RKQRKAKESRERSAQRMESILQALESIQMDLEAVNIKAGKAFLRLKRKFIQMRRPFLERRDLIIQHIPGFWVKAFLNHPRISILINQRDEDIFRYLTNLQVQDLRHI-----SMGYKMKLYFQ-TNPYFTNMVIVKEFQRN------RSGRLVSHSTPIRWHRGQ---------EPQVYNRRSHD--TRESFFNWF------SNHSLPEADRIAEIIKNDLWVNPVRYYMRGGGYRTSRKKQLGKESRAKNQYEMVIMEDAHDHYAVEDILSEISEIDEITDNETIHDIKISDFMETTDYFETTDNEVTDANENLCDSENPDHSEGS-HKITDNKGSIATGPDDNGDKPEEKNTYDSEDSNSEKADGDNKTLEGDNQQVTNIQDSSDSDNGDEGSDDEDDDGNEGDNEGSDDDD----------RDIKYYKNGFEVFDKALDNRTIQDVYEEEVEIISEDSVEEEEEETSEEASELSEDSYEDERVYEEEGSEVNSEDSDIQEVLPVPNAWASLGKKGKIG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A494C1R9-1", "uniprot_id": "TSPY9_HUMAN", "id": "A0A494C1R9-1", "name": "Testis-specific Y-encoded protein 9", "aln": "-------------------------------------------MRPEGSLTYRVPERLRQGFCG-------------VGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEV-------------------VAEVEVVAEEEGLVERREEAQR---------AQQAVP-----GPGPMT----------------------------------------------PESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKPQLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVEEEKHP-----VHLCKIMLFFR-SNPYFQNKVITKEYLVN------ITEYRASHSTPIEWYPDY---------EVEAYRRRHHN--SSLNFFNWF------SDHNFAGSNKIAEILCKDLWRNPLQYYKRM---------------KPPEEGTETSGDSQLLS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CV99-1", "uniprot_id": "TSPY4_HUMAN", "id": "P0CV99-1", "name": "Testis-specific Y-encoded protein 4", "aln": "-------------------------------------------MRPEGSLTYRVPERLRQGFCG-------------VGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEV-------------------VAEVEVVAEEEGLVERREEAQR---------AQQAVP-----GPGPMT----------------------------------------------PESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVEEEKHP-----VHLCKIMLFFR-SNPYFQNKVITKEYLVN------ITEYRASHSTPIEWYPDY---------EVEAYRRRHHN--SSLNFFNWF------SDHNFAGSNKIAEILCKDLWRNPLQYYKRM---------------KPPEEGTETSGDSQLLS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CV98-1", "uniprot_id": "TSPY3_HUMAN", "id": "P0CV98-1", "name": "Testis-specific Y-encoded protein 3", "aln": "-------------------------------------------MRPEGSLTYRVPERLRQGFCG-------------VGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEV-------------------VAE------EEGLVERREEAQR---------AQQAVP-----GPGPMT----------------------------------------------PESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVEEEKHP-----VHLCKIMLFFR-SNPYFQNKVITKEYLVN------ITEYRASHSTPIEWYPDY---------EVEAYRRRHHN--SSLNFFNWF------SDHNFAGSNKIAEILCKDLWRNPLQYYKRM---------------KPPEEGTETSGDSQLLS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CW01-1", "uniprot_id": "TSPYA_HUMAN", "id": "P0CW01-1", "name": "Testis-specific Y-encoded protein 10", "aln": "-------------------------------------------MRPEGSLTYRVPERLRQGFCG-------------VGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEV-------------------VAE------EEGLVERREEAQR---------AQQAVP-----GPGPMT----------------------------------------------PESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVEEEKHP-----VHLCKIMLFFR-SNPYFQNKVITKEYLVN------ITEYRASHSTPIEWYPDY---------EVEAYRRRHHN--SSLNFFNWF------SDHNFAGSNKIAEILCKDLWRNPLQYYKRM---------------KPPEEGTETSGDSQLLS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CW00-1", "uniprot_id": "TSPY8_HUMAN", "id": "P0CW00-1", "name": "Testis-specific Y-encoded protein 8", "aln": "-------------------------------------------MRPEGSLTYWVPERLRQGFCG-------------VGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEV-------------------VAE------EEGLVERREEAQR---------AQQAVP-----GPGPMT----------------------------------------------PESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVEEEKHP-----VHLCKIMLFFR-SNPYFQNKVITKEYLVN------ITEYRASHSTPIEWYLDY---------EVEAYRRRHHN--SSLNFFNWF------SDHNFAGSNKIAEILCKDLWRNPLQYYKRM---------------KPPEEGTETSGDSQLLS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q01534-1", "uniprot_id": "TSPY1_HUMAN", "id": "Q01534-1", "name": "Testis-specific Y-encoded protein 1", "aln": "-------------------------------------------MRPEGSLTYRVPERLRQGFCG-------------VGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEV-------------------VAE------EEGLVERREEAQR---------AQQAVP-----GPGPMT----------------------------------------------PESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHP-----VHLCKIMLFFR-SNPYFQNKVITKEYLVN------ITEYRASHSTPIEWYPDY---------EVEAYRRRHHN--SSLNFFNWF------SDHNFAGSNKIAEILCKDLWRNPLQYYKRM---------------KPPEEGTETSGDSQLLS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NKD2-1", "uniprot_id": "TSPY2_HUMAN", "id": "A6NKD2-1", "name": "Testis-specific Y-encoded protein 2", "aln": "-------------------------------------------MRPEGSLTYRVPERLRQGSCG-------------VGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEV-------------------VAE------EEGLVERREEAQR---------AQQAVP-----GPGPMT----------------------------------------------PESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVEEEKHR-----VHLCKIMLFFR-SNPYFQNKVITKEYLVN------ITEYRASHSTPIEWYPDY---------EVEAYRRRHHN--SSLNFFNWF------SDHNFAGSNKIAEILCKDLWRNPLQYYKRM---------------KPPEEGTETSGDSQLLS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R1M3-1", "uniprot_id": "TSPY1_RAT", "id": "Q9R1M3-1", "name": "Testis-specific Y-encoded protein 1", "aln": "-------------------MENSEEESVGVAPQEFRELVLLESSLLEGEPSVQAPEQSPGAPAG-------------DNQMVKPLVICGPVEDWVPLAEVLHHPDTCEEGDEATMAELKVTEVVDVKNEGEE-------------------VKD----QKQEGEQDQQPELEKNPEQACDSKDQQGIQRLPLSGGGPAE----------------------------------------------RRSKMEELELLQLELSFVNARCSGAFARIKAKVAKMRRPHFDRRKTIIQGIPGFWAKAMMNHPQMSSIISNQDEDLLSYMLSLEVEEYNPG-----LRMCRMMFFFS-ENPYFRNDIVTKDYQLS------IIGYKESDSSTIEWIGQA---------EHGYANCMQDT--TRLTFFNWL------CAHKFPGSNRIAEIIMDDLWPNPLYYY-------------------PKEDHS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q69ZB3-1", "uniprot_id": "TSYL5_MOUSE", "id": "Q69ZB3-1", "name": "Testis-specific Y-encoded-like protein 5", "aln": "---MSGRSRGRKSSRAKGRGKGRARARVRAAAEDAWHDEKPPQSPRLGEDSAAAQVQAGAAQGGAEPAE------LREEAACRLPLDCGLALRARAADERGLAAPDPDLERARSLAERLTSDTSFVGTVGALAKLRRGSRIGNRRVP-GRKAPDTRSATGRGPQATVSGKPKMASAGLCAAAPVGEEKKMTEKHAGAGS--------------------------------------------PATVGSMDTLETVQLKLETMNAQADRAYLRLSRKFGQLRLHHLERRNLLIQSIPGFWGQAFQNHPQLSAFLNTKDKEVLSYLNRLEVEELGLA-----RLGYKIKFYFG-RNPYFQNKVLIKEYGCG------PSGQVVSRSAPIQWLPGH---------DLQSLSKENPE--NNGSFFGWF------SNHSSIESDKIVEIINEDLWPNPLQYYLISEEARGEKGKE-ERP-GPAKL---SPAPAVRQPN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZLU5-1", "uniprot_id": "D3ZLU5_RAT", "id": "D3ZLU5-1", "name": "Testis-specific Y-encoded-like protein 5", "aln": "---MSGRSRGRRSSRAKGRGKGRARARVPAAADDIWRDEKPAQSPRLGEDAAAAQVQDGTAHGGTEPAE------PGEAEACRLPLDCGLALRARAAGECGLAAPDPGLERATALAERLTSDISFVGTVGALAKLRQGSRIGNRRVP-GRKAPGPRSATGRGPQATVSGKPKMGSARPCAAAPVGEEKKVTEKHAGSGS--------------------------------------------PAAVGSMDTLETVQLKLETMNAQADRAYLRLSRKFGQLRLHHLERRNLLIQSIPGFWGQAFQNHPQLSSFLNTKDKEVLSYLNRLEVEELGLA-----RLGYKIKFYFG-RNPYFQNKVLIKEYGCG------PSGQVVSRSAPIQWLPGH---------DLQSLSKENPE--NNGSFFGWF------SNHSSIESDKIVEIINEDLWPNPLQYYLISEEAHGEKGKE-ERPPGPAKQPVESPKPAVRQPN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86VY4-1", "uniprot_id": "TSYL5_HUMAN", "id": "Q86VY4-1", "name": "Testis-specific Y-encoded-like protein 5", "aln": "---MSGRSRGRKSSRAKNRGKGRAKARVRPAPDDAPRDPDPSQYQSLGEDTQAAQVQAGAGWGGLEAAASAQLLRLGEEAACRLPLDCGLALRARAAGDHGQAAARPGPGKAASLSERLAADTVFVGTAGTVGRPKNAPRVGNRRGPAGKKAPETCSTAGRGPQVIAGGRQKKGAAGENTSVSAGEEKKE-ERDAGSGP--------------------------------------------PATEGSMDTLENVQLKLENMNAQADRAYLRLSRKFGQLRLQHLERRNHLIQNIPGFWGQAFQNHPQLASFLNSQEKEVLSYLNSLEVEELGLA-----RLGYKIKFYFD-RNPYFQNKVLIKEYGCG------PSGQVVSRSTPIQWLPGH---------DLQSLSQGNPE--NNRSFFGWF------SNHSSIESDKIVEIINEELWPNPLQFYLLSEGARVEKGKEKEGRQGPGKQPMETTQPGVSQSN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VD63-1", "uniprot_id": "TSYL4_MOUSE", "id": "Q8VD63-1", "name": "Testis-specific Y-encoded-like protein 4", "aln": "--------------MNGVEGNNELSLANTTTPSHASEDLDLKQDQGLQEETDTVREMEAAGEAG------------ADGGASPDSEHCGPELCFRVAEN-SCAAAARGLEDAPSPSKGGDAPSAPVAADDSS---KNGCQLEGPHSPAKPKALEACGAVGLGSQQMPGPK-KTKEMTTTKCAISVATGKEGEAGAAMQE--------KKGLQKEKKVAGG--------------GKEETRPR-APKINCMDSLEAIDQELSNVNAQADRAFLQLERKFGRMRRLHMQRRSFIIQNIPGFWVTAFRNHPQLSPMISGQDEDMMRYMINLEVEELKQP-----RVGCKFKFIFQ-SNPYFRNEGLVKEYERR------SSGRVVSLSTPIRWHRGQ---------EPQAHIHRNREGNTIPSFFNWF------SDHSLLEFDRIAEIIKGELWSNPLQYYLMGDGPR-------RGVRVPPRQPVESPRSFRFQSG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0U9-1", "uniprot_id": "TSYL1_HUMAN", "id": "Q9H0U9-1", "name": "Testis-specific Y-encoded-like protein 1", "aln": "-----------MSGLDGVKRTTPLQTHSIIISDQVPSDQDAHQYLRLRDQSEATQVMAEPGEGGSETVALPPPPPSEEGGVPQDAAGRGGTPQIRVVGGRGHVAIKAGQEEGQPPAEGLAAASVVMAADRSL---KKGVQGG-------EKALEICGAQRSASELTAGAEAEAEEVKTGKCATVSAAVAERESAEVVKEGLAEKEVMEEQMEVEEQPPEGEEIEVAEEDRLEEEAREEEGPWPLHEALRMDPLEAIQLELDTVNAQADRAFQQLEHKFGRMRRHYLERRNYIIQNIPGFWMTAFRNHPQLSAMIRGQDAEMLRYITNLEVKELRHP-----RTGCKFKFFFR-RNPYFRNKLIVKEYEVR------SSGRVVSLSTPIIWRRGH---------EPQSFIRRNQD--LICSFFTWF------SDHSLPESDKIAEIIKEDLWPNPLQYYLLREGVR-------RARRRPLREPVEIPRPFGFQSG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9EQU5-1", "uniprot_id": "SET_MOUSE", "id": "Q9EQU5-1", "name": "Protein SET", "aln": "---------------------------------------------------------------------------------------------MAPKRQSAILPQPKKPRPAAAPKLEDKSASPGLPK-GEK----------------------------------------------------------------------------------------------------------------EQQEAIEHIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPFFQKRSELIAKIPNFWVTTFVNHPQVSALLGEEDEEALHYLTRVEVTEFEDI-----KSGYRIDFYFD-ENPYFENKVLSKEFHLN-----ESGD-PSSKSTEIKWKSGKDLT--KRSSQTQNKASRKRQHEEPESFFTWF------TDHSDAGADELGEVIKDDIWPNPLQYYLVPDMDD-----------EEGEAEDDDDDDEEEEG---LEDIDEEGDEDEGEEDDDEDEGEEGEEDEGEDD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63945-1", "uniprot_id": "SET_RAT", "id": "Q63945-1", "name": "Protein SET", "aln": "---------------------------------------------------------------------------------------------MAPKRQSAILPQPKKPRPVAAPKLEDKSASPGLPK-GEK----------------------------------------------------------------------------------------------------------------EQQEAIEHIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPFFQKRSELIAKIPNFWVTTFVNHPQVSALLGEEDEEALHYLTRVEVTEFEDI-----KSGYRIDFYFD-ENPYFENKVLSKEFHLN-----ESGD-PSSKSTEIKWKSGKDLT--KRSSQTQNKASRKRQHEEPESFFTWF------TDHSDAGADELGEVIKDDIWPNPLQYYLVPDMDD-----------EEGEAEDDDDDDEEEEG---LEDIDEEGDEDEGEEDDDEDEGEEGEEDEGEDD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01105-1", "uniprot_id": "SET_HUMAN", "id": "Q01105-1", "name": "Protein SET", "aln": "---------------------------------------------------------------------------------------------MAPKRQSPLPPQKKKPRPPPALGPEETSASAGLPKKGEK----------------------------------------------------------------------------------------------------------------EQQEAIEHIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPFFQKRSELIAKIPNFWVTTFVNHPQVSALLGEEDEEALHYLTRVEVTEFEDI-----KSGYRIDFYFD-ENPYFENKVLSKEFHLN-----ESGD-PSSKSTEIKWKSGKDLT--KRSSQTQNKASRKRQHEEPESFFTWF------TDHSDAGADELGEVIKDDIWPNPLQYYLVPDMDD-----------EEGEGEEDDDDDEEEEG---LEDIDEEGDEDEGEEDEDDDEGEEGEEDEGEDD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DME0-2", "uniprot_id": "SETLP_HUMAN", "id": "P0DME0-2", "name": "Protein SETSIP", "aln": "---------------------------------------------------------------------------------------------MAPKRQSPLPLQKKKPRPPPALGLEETSASAGLPKKGEK----------------------------------------------------------------------------------------------------------------EQQEAIEHIDEVQNEIDRLNEQDSEEILKVEQKYNKLRQPFFQKRSELIAKIPNFGVTTFVNHPQVSSLLGEEDEEALHYLTKVEVTEFEDI-----KSGYRIDFYFD-ENPYFENKVFSKEFHLN-----ESGD-PSSKSTKIKWKSGKDVT--KRSSQTQNKASRKRQHEEPESFFTWF------TDHSDAGADELEEVIKDDIWPNPLQYYLVPDMDD-----------EEGGEDDDDDDDDGDEGEEELEDIDE-GDEDEGEEDEDDDEGEEGEEDEGEDD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53997-1", "uniprot_id": "SET_DROME", "id": "P53997-1", "name": "Protein SET", "aln": "-----------------------------------------------------------------------------------------------------MSSVPKRAKLDGAPADGNTSAAAGNNE--------------------------------------------------------------------------------------------------------------------EESEALEQIDACQNEIDALNEKASEEILKVEQKYNKLRKPCYEKRSELVKRIPNFWVTSFINHPQVSGILDEEEEECLHALNKLEVEEFEDI-----KSGYRINFHFD-ENPYFENKVLTKEFHLNSAAASENGDWPASTSTPIKWKEGKNLL--K-LLLTKPYGNKKKRNSEYKTFFDWF------SDNTDPVNDEIAELIKDDLWPNPLQYYLVPDIEV-----------EPEDEEDNEDNDE--------EAFDD--------EDGEDGEGEEEEEDEDDK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53853-1", "uniprot_id": "VPS75_YEAST", "id": "P53853-1", "name": "Vacuolar protein sorting-associated protein 75", "aln": "--------------------------------------------------------------------------------------------------------------MMSDQENENEHAKAFLG----------------------------------------------------------------------------------------------------------------------LAKCEEEVDAIEREVELYRLN--------------KMKPVYEKRDAYIDEIAEFWKIVLSQHVSFANYIRASDFKYIDTIDKIKVEWLALESEMYDTRDFSITFHFHGIEGDFKEQQVTKVFQIKKGKDDQEDGILTSEPVPIEWPQSYDSINPDLIKDKRSPEGKKKYRQGMKTIFGWFRWTGLKPGKEFPHGDSLASLFSEEIYPFCVKYYAEAQRDLED---------EEGESGLSADGDSEDDDGSLGEVDLPLSDEEPSSKKRKV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : .:. . . ::* : :. * : :* .: : : . : : ::* : : * : * : . * : * . * * .:* *: : : : .:: ::: : :* ", "identical_positions": 13, "similar_positions": 45, "identity": "1.73%" }, { "cls_id": "homologset.agr.SGD:S000005191", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ER72-1", "uniprot_id": "SYCC_MOUSE", "id": "Q9ER72-1", "name": "Cysteine--tRNA ligase, cytoplasmic", "aln": "MAGSSAEQAADYRSILSISDEAARVQALDQHLSTRSYIQGYSLSQADVDVFRQLSAPPADSRLFHVARWFRHIEALLGGPQGRDEPCRLQASKGRRVQPQWSPP-AGTEPCRLRLYNSLTRNKDVFIPQDGKK-VTWYCCGPTVYDASHMGHARSYISFDILRRVLRDYFQYDVFYCMNITDIDDKIIRRARQNYLFEQYR--EQKPPATQLLKDVRDAMKPFSVKLSETTDPDKRQMLERIQNSVKLATEPLEQ----------AVRSSLSGEEVDS--KVQVLLEEAKDLLSDWLDSTGGSEVTDNSIFSKLPKFWEEEFHKDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYAS-NGSVYFDTAKFAASEKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFMNEFFLNVKDILRAPVDITG--QFEKWEAEEVELNKNFYGKKTAVHEALCDNIDTRTVMEEMRALVSQCNLYMAARKAERRRPNRALLENIAMYLTHMLKIFGAIE-EESPLGFPVGG----PGTNLNLESTVMPYLQVLSEFREGVRKIAREKK-VLEVLQLSDALRDDILPELGVRFEDHEGLPTVVKLVDRDT---LLKEKEGKKRAEEEKRRKKEEAARKKQEQEAAKLAKMKIPPSEMFLSEVNKYSKFDENGLPTHDTEGKELSKGQAKKLKKLFEAQEKLYKEYLQMLQNGSLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5Y9V4-1", "uniprot_id": "A0A8I5Y9V4_RAT", "id": "A0A8I5Y9V4-1", "name": "Cysteine--tRNA ligase, cytoplasmic", "aln": "MAGSSAEQAADYRSILSISDEAARVQALDQHLSTRSYIQGYSLSQADVDVFRQFSAPPADSRLFHVARWFRHIEALLGGPQGRGEPCRLQASKGRRVQPQWSPP-AGTEPCRLRLYNSLTRNKDVFIPQDGKK-VTWYCCGPTVYDASHMGHARSYISFDILRRVLRDYFQYDVFYCMNITDIDDKIIRRARQNYLFEQYR--EQKPSAAQLLKDVGDAMKPFSVKLSETTDPDKRQMLERIQNSVKLATEPLEQ----------AVHSNPSGEEVDS--RVQVLLEEAKDLLSDWLDSTGGSEVTDNSIFSKLPKFWEEEFHKDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYAS-NGSVYFDTAKFAASEKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGSLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFMNEFFLNVKDILRAPVDITG--QFEKWEAEEVELNKNFYDKKTAVHEALCDNIDTRTVMEEMRALVSQCNLYMAARKAARRRPNRALLENIAMYLTHMLKIFGAIE-EENPLGFPVGG----PGTNLNLESTVMPYLQVLSEFREGVRKIAREKK-VLEVLQLSDALRDDILPELGVRFEDHEGLPTVVKLVDRDT---LLKEKEEKKRAEEEKRRKKEEAARKKQEQEAAKLAKMKTPPSEMFRSETDKYSKFDENGLPTHDTEGKELSKGQTKKLKKLFEAQEKVYKEYLQQLQNSSLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49589-1", "uniprot_id": "SYCC_HUMAN", "id": "P49589-1", "name": "Cysteine--tRNA ligase, cytoplasmic", "aln": "---------------------------------------------------------MADS----------------SGQQG----------KGRRVQPQWSPP-AGTQPCRLHLYNSLTRNKEVFIPQDGKK-VTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFDVFYCMNITDIDDKIIKRARQNHLFEQYR--EKRPEAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQHAVQLATEPLEK----------AVQSRLTGEEVNS--CVEVLLEEAKDLLSDWLDSTLGCDVTDNSIFSKLPKFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVS-NGSVYFDTAKFASSEKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFLNEFFLNVKDILRAPVDITG--QFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEMRALVSQCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVE-EDSSLGFPVGG----PGTSLSLEATVMPYLQVLSEFREGVRKIAREQK-VPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLVDRNT---LLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQNGSFQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KN90-1", "uniprot_id": "SYCC_DROME", "id": "Q7KN90-1", "name": "Cysteine--tRNA ligase, cytoplasmic", "aln": "--------------------------------------------------------------------------------------------MSKRGQPAWQAP-EAVDRPKLKLFNSLTRQKEDFVPLDGNN-VTWYSCGPTVYDASHMGHARSYISFDILRRILSDYFGYNIHYVMNITDIDDKIIRRARQNHLFDEYAAEAQKLPLDELLGQQKEVLQRFQDTCAKNTDPDKKIMLDKTLQRMNDAVEALTK----------AVGKG-DEREISE--KRLLYLNEAKDPISDWLDSLKGAQINDNAVFEALPRYWEDQFHNDMKSLNILPPDVLTRVSEYVPQIVTFIQKIIDNGLAYAA-NNSVYFDVNGFDKREKHHYAKLVPEAYGDTKSLQEGEGDLSIAEDRLSEKRSANDFALWKASKAGEPWWDSPWGKGRPGWHIECSAMASDIFGPTFDIHTGGVDLKFPHHDNELAQSEAAFNESEWVKYFLHTGHLTIAGCKMSKSLKNFVTIQEALKKHSATQLRLAFLLHSWKDTLDYSENTMEMATQYEKFLNEFFLNVKDLTRHVLSEEPRRQFDAWTEVEAALQKKFSNAQVQVHASLCDNIDTRSALDAIRELVSVSNVYIRDNKT---RLNSLLLRNVATYITDLLHVFGAISGPRGGIGFPVSGGSGAQAAGADLETTVLPYVQSLAEFRYLVREQAKTLK-AFDILKLCDDLRDNVLPNLGVRLEDKDIGKYAVKLVDRDS---LLREREAKLAAEAEKAAEKERKKQAAAEAAAAKEAQRRVNPKEMFLAETEKYSAFDENGLPTHDKEGKEVSKGQIKKLQKLQQQQEQRYNEYLASIEKA---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53852-1", "uniprot_id": "SYC_YEAST", "id": "P53852-1", "name": "Cysteine--tRNA ligase", "aln": "-----------------------------------------------------------------------------MNIFIKALRRYTIMSTPKIVQPKWKVPTPQAKETVLKLYNSLTRSKVEFIPQSGNRGVTWYSCGPTVYDASHMGHARNYVSIDINRRIIQDYFGYDVQFVQNVTDIDDKIILRARQNYLFDNFVKENDTKFNATVVDKVKTALFQYINKNFTIQGSEIKTIEEFETWLSNADTETLKLENPKFPMHVTAVQNAIESITKGDSMDAEVAFEKVKDVTVPLLDKELGSTISNPEIFRQLPAYWEQKFNDDMLSLNVLPPTVTTRVSEYVPEIIDFVQKIIDNGYAYATSDGSVYFDTLKFDKSPNHDYAKCQPWNKGQLDLINDGEGSLSNFAD--NGKKSNNDFALWKASKAGEPEWESPWGKGRPGWHIECSVMASDILGSNIDIHSGGIDLAFPHHDNELAQSEARFDNQQWINYFLHTGHLHIEGQKMSKSLKNFITIQEALKKFSPRQLRLAFASVQWNNQLDFKESLIHEVKSFENSMNNFFKTIRALKNDAASAGH--ISKKFSPLEKELLADFVESESKVHSAFCDNLSTPVALKTLSELVTKSNTYITTAGA---ALKIEPLIAICSYITKILRIIGFPS-RPDNLGWAAQAGSN-DGSLGSLEDTVMPYVKCLSTFRDDVRSLAIKKAEPKEFLQLTDKIRNEDLLNLNVALDDRNGQSALIKFLTNDEKLEIVKLNEEKHANELAKKQKKLEQQKLREQKENERKQKAQIKPQDMFK-DVTLYSAWDEQGLPTKDKDGNDITKSMTKKLKKQWEQQKKLHEEYFGEDK-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** *. * .. *:*:*****.* *:* .*:. ****.***************.*:*:** **:: *** ::: : *:******** *****:**::: . :: . .: : . ..: : : : : .*.* ** . .. : :::.** **. *. :.: :* ** :** .*: ** :**:*** * ********:*: *:***:*** .*.: :.*****. * :* *.* * *: . :::***.** * . *:* **********.*** * .**************.**. ::*..:*** **.** ************* *::. *:.******** * * *********:**::****.*. ****** .*:: **:... :. . .:*: :*:** .:: : . . . : * * .* : :* ::***:.* .:. : **: .* *: : : * :. *:*.:*:::* . . :*:.. . .: .** **:**:: *: ** **. * :.*:* * :*:: * :*.* ::*:: :*:: .: ::: .* * * * :* . : : : : : *.:** :. ** :**:****:* :*::::*. ***:* : *:: ::**: : ", "identical_positions": 275, "similar_positions": 213, "identity": "32.01%" }, { "cls_id": "homologset.agr.SGD:S000005192", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7ESP7-1", "uniprot_id": "F7ESP7_RAT", "id": "F7ESP7-1", "name": "", "aln": "MATPDSPGMDGQTGDTETEVLQSARWQYCGEPDDRQKAVLVQFSNGKLQNPGNMRFTLYNSTDLVNPRQKCHRILAAETDRLSYVGNNFGTGALKCNTLCRHFVGILNKTSGQMEVYDAEVFNMQPLFA------------------------------------------------EDSIEHGPPLENQNKTFRDKLDSCI-EAFGSTKQKRSLNSRRMNKVGSESLNFTVAKAAES-IIDTKGVSALVSDAMQDDLQNDSLYLPPCHADATKPEDVYRFEDILSPAEYDALESPSEAFRKVMSEDILKMVEENRSVVTGCWEWPRGVVENKLEFSARAAILYHCSFIIEMLKSLPADEVQRNRQARSIWFLDALLRFRAQKVIKGKSALGP---GIPHIINTKLLKQFTCLTYN-NGSLRN---LISSSMKAKITAYAIILALHINNFQIDLTVLQRDLKLSEKRMIEIARAMRLKISKRKVSLADGR------EEDHRLGTLSVPLPPAQTSDRQSKRKKMS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K202-1", "uniprot_id": "RPA49_MOUSE", "id": "Q8K202-1", "name": "DNA-directed RNA polymerase I subunit RPA49", "aln": "MATLESPGMDDQAGDTETEALQSARWLYCGEPDDRQKAVLVQFSNGKLQNPGDMRFTLYNSTDLVNPRQRSHRIVAAETDRLSYVGNNFGTGALKCNALCRHFVGILNKTSGQMEVYDAELFNMQPLFAGMGTEVIKLGGQHLYLLAFCQPSKNLAEAGDLLLSRHRQGHCIAVLLDDDAIEREPPLENQNKTFRDKLDSCI-EAFGSTKQKRSLNSRRMNKVGSESLNLSVAKAAES-IIDTKGVNALVSDAMQDDLQDGVLYLPPCYADAAKPEDVYRFEDILSPAEYDALESPSEAFRKVTSEDILKMIEENS----------------------------HCSYVIEMLKSLPIDEVHRNRQARSIWFLDALIRFRAQKVIKGKRALGP---GIPHIINTKLLKQFTCLTYN-NGRLQN---LISSSMRAKITSYAIILALHINNFQVDLTALQKDLKLSEKRMIEIAKAMRLKISKQKVSLADGR------EESHRLGTLSVPLPPAQNSDRQSKRRKMN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZS1-2", "uniprot_id": "RPA49_HUMAN", "id": "Q9GZS1-2", "name": "DNA-directed RNA polymerase I subunit RPA49", "aln": "---------------MAAEVLPSARWQYCGAPDGSQRAVLVQFSNGKLQSPGNMRFTLYENKDSTNPRKRNQRILAAETDRLSYVGNNFGTGALKCNTLCRHFVGILNKTSGQMEVYDAELFNMQPLFS------------------------------------------------DVSVESELALESQTKTYREKMDSCI-EAFGTTKQKRALNTRRMNRVGNESLNRAVAKAAET-IIDTKGVTALVSDAIHNDLQDDSLYLPPCYDDAAKPEDVYKFEDLLSPAEYEALQSPSEAFRNVTSEEILKMIEENS----------------------------HCTFVIEALKSLPSDVESRDRQARCIWFLDTLIKFRAHRVVKRKSALGP---GVPHIINTKLLKHFTCLTYN-NGRLRN---LISDSMKAKITAYVIILALHIHDFQIDLTVLQRDLKLSEKRMMEIAKAMRLKISKRRVSVAAGS------EEDHKLGTLSLPLPPAQTSDRLAKRRKIT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q01080-1", "uniprot_id": "RPA49_YEAST", "id": "Q01080-1", "name": "DNA-directed RNA polymerase I subunit RPA49", "aln": "-----------------MSVKRSVSEIEIESVQDQPSVAVGSFFKG-FRAPSDTTFDLYKKKK----SEKDEFVLHGENERLEYEGYTDSS----SQASNQYVVGLFNPEKKSIQLYKAPVLVSKVVSK------------------------------------------------SSKNLRGPKIKSKSDTRPSALRNALGEAFGTKKAKKAIADLERNRIDSDKLTDSAIDIVDS-VRTAS--KDLPTRAQLDEITSNDRPTPLANIDATDVEQIYPIESIIPKKELQFIRVSS-ILKEADKEKKLELFPYQN----------------------------NSKYVAKKLDSLTQPS--QMTKLQLLYYLSLLLGVYENRRVNNKTKLLERLNSPPEILVDGILSRFTVIKPGQFGRSKDRSYFIDPQNEDKILCYILAIIMHLDNFIVEITPLAHELNLKPSKVVSLFRVLGAIVKGATVAQAEAFGIPKSTAASYKIATMKVPFKLPEMTRRGRGPRR--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VE94-1", "uniprot_id": "Q9VE94_DROME", "id": "Q9VE94-1", "name": "", "aln": "------------------MEDKIIIESVCDHKRDENIPTILKFQNG--SLLGDADFSMVES------------TVDGKKHALVYAGDQVYTGEVKDSEEVDTYIFIRNKLTNKVKVVPVQEALMYNHVY---------------------------------------------------KKLERQKRTGPTMSREHANKKLLKEFGGRKASRFVDNREQMMVNVEVMRQDLDETVNSSMLNEDEEDGTLGDVSINNEEYLASIVPEFNKEATKVDEVYAVESLIPSSLLERLEEEAKVVFSTPVQTLPIKSEYLK-------------------------------SCLAKIQENPVSSKRDFLHIKLIIYMDALQSLISLRSRQMQKAELS---GITEKIENDIRHRFADPNVAKKGTRTN------FSSEKALTHFIVMALLLSEKFEVDINVLSRALATTKARIKQYAHIVNALPK-----------------SNSDILSLRLPSKVPALKSGRRFQRKK-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: .* :* .: * : :. : .:.. * * * : . : : * . .::: . .. . . : : ** * .: : . :. : : . .:: : . . :: * :*:. :::* .*.::. : :. : . .. : :.. . : : : ::. * . : : : . .. : : :*: . * : . . : : : : ..* :::. * : * . :: . : : . . : :: :* . . :: ", "identical_positions": 21, "similar_positions": 119, "identity": "4.0%" }, { "cls_id": "homologset.agr.SGD:S000005193", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AJL3-1", "uniprot_id": "FGGY_MOUSE", "id": "A2AJL3-1", "name": "FGGY carbohydrate kinase domain-containing protein", "aln": "MMSGRDQEPSRYYVGIDVGTGSVRAALVDQR-GLLLAFAEQPIKKWEPQFN---HHEQSSEDIWAACCLVTKEVVQGIDAHRIRGLGFDATCSLVVLDKEFHPLPVNHEGDSSRNVIMWLDHRAVSQVHRIN-ETKHRVLQYVGGVMSVEMQAPKLLWLKENLREICWDKAGHFFDLPDFLSWKATGVTARSLCSLVCKWTYSAEKG-WDDSFWKMIGLEDLIDDNYSKIGNLVLLPGAALGIGLTPEAARELGLPSGIAVAASLIDAHAGGLGVIGADVRGHGLTCEGQPVTSRLAVICGTSSCHMG-ISKDPVFVPGVWGPYYSAMVPG--FWLNEGGQSVTGKLIDHMVQGHPAFPELQAKATARCQSIYAYLNSHLDLIKKAQ---PVGFLTVDLHVWPDFHGNRSPLADLTLKGMVTGLTLSQDLDDLAILYLATVQAIAFGTRFIIETMEAAGHS--LSTLFLCGGLSKNPLFVQMHADITGMPVVLS--QEVESVLVGAAILGACASGDFTSVQEAMARMSKVG-----------KVVFPEHADKKYYDKKYQVFLRMVEHQKEYSAIMNGS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96C11-1", "uniprot_id": "FGGY_HUMAN", "id": "Q96C11-1", "name": "FGGY carbohydrate kinase domain-containing protein", "aln": "-MSGGEQKPERYYVGVDVGTGSVRAALVDQS-GVLLAFADQPIKNWEPQFN---HHEQSSEDIWAACCVVTKKVVQGIDLNQIRGLGFDATCSLVVLDKQFHPLPVNQEGDSHRNVIMWLDHRAVSQVNRIN-ETKHSVLQYVGGVMSVEMQAPKLLWLKENLREICWDKAGHFFDLPDFLSWKATGVTARSLCSLVCKWTYSAEKG-WDDSFWKMIGLEDFVADNYSKIGNQVLPPGASLGNGLTPEAARDLGLLPGIAVAASLIDAHAGGLGVIGADVRGHGLICEGQPVTSRLAVICGTSSCHMG-ISKDPIFVPGVWGPYFSAMVPG--FWLNEGGQSVTGKLIDHMVQGHAAFPELQVKATARCQSIYAYLNSHLDLIKKAQ---PVGFLTVDLHVWPDFHGNRSPLADLTLKGMVTGLKLSQDLDDLAILYLATVQAIALGTRFIIEAMEAAGHS--ISTLFLCGGLSKNPLFVQMHADITGMPVVLS--QEVESVLVGAAVLGACASGDFASVQEAMAKMSKVG-----------KVVFPRLQDKKYYDKKYQVFLKLVEHQKEYLAIMNDD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZJ8-1", "uniprot_id": "Q9VZJ8_DROME", "id": "Q9VZJ8-1", "name": "FGGY carbohydrate kinase domain-containing protein", "aln": "-MSSGP-----FFVGVDVGTGSARAALVACD-GRVLEQAVQTIQTWNPEPG---YYNQSSDNIWQSICQVVKKVIGGVDKSKVKGIGFDATCSLVVLGPQGSPLTVSKSGEAEQNIILWMDHRAEQETQEIN-AFKHSLLKYVGGQVSLEMEVPKLLWLKRNLSQT-FGNIWRVFDLPDFLTWRATGVDTRSLCSVVCKWNYDAANGSWNKEFLKQADLEELTQNNFEKLGSDVQPPGRTVGKGLTAKAAGELGLSAGTVVSTSLIDAHAGALGMFGCRSKES---KGADDVQGKMALIAGTSTCHMS-ITRKACFAQGVWGPYQDAIIPG--YFLNEGGQSIAGHLLDHVLKSHESYAELKSQLGE-DKFIYQHLNKLLPELAAARGLSQVGCLTQDVHVWPDLHGNRSPIADPTLRGVITGLDMTRGTESLAIKYLAFVQALAYGTRHIIENLYQYGRAP-FQTLLFCGGLAKNPLYVQCHADICNLPALIP--DEQEMVLVGAAALGAAASGHFDSLESASKSMGGTG-----------QLVKPNAETLEFHNRKYKVFLQLLENQRQYRRIMQADTK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53583-1", "uniprot_id": "MPA43_YEAST", "id": "P53583-1", "name": "Protein MPA43", "aln": "-MNSSLQVG----IGIDVGSSSARIGVYNYYNDALLEMAQEPVPYYQDSSKKSWKFWQKSTEIIKALQKCLQKLN--IREYEVKSCGVSATCSLAIFERDRTSNMLIPYPN-EDNVIFWMDSSAVNECQWLNMQCPQQLLDYLGGKFVPEMGVPKLKYFLDEYSHL-RDKHFHIFDLHQYIAYELS---------RLYEWNIEGLLG---RENLNGIGNDGEVSGWSSSFYKNIINLPSNVSIGTTSLVANKH---ISTTVVRSCIDSYASWFAVASP------------HLETSLFMIAGTSSCYMYGTTISDTRIPGVWGPFDTILDNRGDFSVYAAGQSCTGKLIEHLFESHPCARKILKDGAD----IYQVLEQTIRDIEKNNG-LSIHILTKDMFFYGDYEGNRTPFADPRIKGSFIGESTDTSMLNLTYKYICILEFLSFQTKLIIDTFQNENSNIHIKELRISGSQAKNERLLSLISLVNNGVAIIKPKENVDMMGIKGAYVLAKSAKEKKQLADVITERDISNDSEKFESLAEYRLGNDSILLRKLLCVKYHIHLDMAKQQKRYHKLVDEVFQHL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. :*:***:.*.* .: . :* * :.: :: . . *.* :* : ::: : .::. *..*****.:: : . : : *:*:*:* * .: : :* : :*.*:** . ** .*** :: : . .: :.*** :::::. : : :*. .. * . : . : . ..: . : :. * *. .* . . .* * **::*. :.: . : : :*.***:*:* : . *****: : : : .*** :*:*::*:.:.* . :: . ** *:. : : . : ** *:..: * .***:*:** ::* . * . .*: *:. :: :: *: **: : . :. * :.*. :** :. : : . .:: :: : : : .* : * :: . .: .. . . :: : **::.* : ::*:.* ::: ", "identical_positions": 95, "similar_positions": 193, "identity": "16.3%" }, { "cls_id": "homologset.agr.SGD:S000005194", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIL8-1", "uniprot_id": "RAD50_RAT", "id": "Q9JIL8-1", "name": "DNA repair protein RAD50", "aln": "MSRIEKMSTLGVRSFGIEDKDKQIISFFSPLTILVGPNGAGKTTIIECLKYICTGDFPPGT-KGNTFVHDPKVAQETDVRAQIRLQFRDVNGEMVLVQRSMLCSQKSKKTEFKTLEGVITRIKHG------EKVSLSSKCAEIDREMISCLGVSKSVLNNVIFCHQEDSNWPLSEGKALKQKFDEIFSATRYIKALDTLRQVRQTQGQKVKECQTELKYLRQNKEKACEIRDQITSKEAQLASSREIVKAYENELEPLKNRLKEIEHNLSKIMRLDNEIKALDSRKKQMEKDNSELEQKMEKVFQGTDEQLNDLYHNHQRTVREKERRLVDCQRELEKLSK----EARLLNQERAELLVEQGRLQLQADRHQEHIRARDSLIQSLAAHLELDGFERGPFSERQIKNFHELVRERQEREAKTASQLLSDLTDKEALKQRQMDEMRDKKSGLGRMIELKTEILTKKQTELRNVRNELQQLE--GSSDRILELDQELTKAERELSKAEKNSSIETLKAEILNLQSEKADLDRNLRKLDQEMEQLNHHTTTRTQMEMLTKDKTDKDEQIRKIKSRHS-----DELTSLLGY---FPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASAEQNKNHINNELK----KKEEQLSSYEDKLFDVCGSQDFESDLDRLKEDIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPGCQRVFQTEAELQEVISDLQSKLRLAPDKLKSTESELKKKERRRDEMLGLVPMRQSIIDLKEKEIPELRNRLQSVNRDIQRLKNDIEEQETLLGTVMPEEESAK----VCLTDVTIMERFQMELKDVERKIAQQAAKLQG-VDLDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIATNLQRRQQMEEQTVELSTEVQSLNREIKDAKEQINPLEIALEKLQQEKEELIHRKNTSNKMAQDKINDIKEKVKNIHGYMKDIENYIQDGKDDYKKQKETELNEVVIQLNECDKHKEKINKEMGTMRQDIDTKKIQERWLQDNLTLRKRREELKEVEEERKQHLKEMGQMQVLQMKNEHQKLEENIDTIKRNHSLALGRQKGYEEEILHFKKELREPQFRDAEEKYREMMIVMRTTELVNKDLDIYYKTLDHAIMKFHSMKMEEINKIIRDLWRSTYRGQDIEYIEIRSDADENVSASDKRRNYNYRVVMLKGDTALDMRGRCSAGQKVLASLIIRLALAETFCLNCGILALDEPTTNLDRENIESLAHALVEIIKSRSQQRNFQLLVITHDEDFVELLGRSEYVEKFYRVKKNIDQCSEIVKSSINSLGSYVH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70388-1", "uniprot_id": "RAD50_MOUSE", "id": "P70388-1", "name": "DNA repair protein RAD50", "aln": "MSRIEKMSILGVRSFGIEDKDKQIISFFSPLTILVGPNGAGKTTIIECLKYICTGDFPPGT-KGNTFVHDPKVAQETDVRAQIRLQFRDVNGEMVAVHRSMLCSQKNKKTEFKTLEGVITRMKHG------EKVSLSSKCAEIDREMISCLGVSKSVLNNVIFCHQEDSNWPLSEGKALKQKFDEIFSATRYIKALDTLRQVRQTQGQKVKECQTELKYLKQNKEKACEIRDQITSKEAQLASSQEIVRSYEDELEPLKNRLKEIEHNLSKIMKLDNEIKALESRKKQMEKDNSELEQKMEKVFQGTDEQLNDLYHNHQRTVREKERRLVDCQRELEKLNK----EARLLNQEKAELLVEQGRLQLQADRHQEHIRARDSLIQSLATHLELDGFERGPFSERQIKNFHELVKERQEREAKTASQLLSDLTDKEALKQRQLDELRDRKSGLGRTIELKTEILTKKQSELRHVRSELQQLE--GSSDRILELDQELTKAERELSKAEKNSSIETLKAEVMSLQNEKADLDRSLRKLDQEMEQLNHHTTTRTQMEMLTKDKTDKDEQIRKIKSRHS-----DELTSLLGY---FPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASAEQNKNHINNELK----KKEEQLSSYEDKLFDVCGSQDLESDLGRLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEVISDLQSKLRLAPDKLKSTESELKKKERRRDEMLGLVPVRQSIIDLKEKEIPELRNRLQSVNRDIQRLKNDIEEQETLLGTIMPEEESAK----VCLTDVTIMERFQMELKDVERKIAQQAAKLQG-VDLDRTVQQVNQEKQEKQHRLDTVTSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIATNLQRRQQMEEQSVELSTEVQSLNREIKDAKEQISPLETALEKLQQEKEELIHRKHTSNKMAQDKINDIKEKVKNIHGYMKDIENYIQDGKDDYKKQKETELNGVAVQLNECEKHREKINKDMGTMRQDIDTQKIQERWLQDNLTLRKRRDELKEVEEEPKQHLKEMGQMQVLQMKNEHQKLEENIDTIKRNHSLALGRQKGYEDEILHFKKELREPQFRDAEEKYREMMIVMRTTELVNKDLDIYYKTLDQAIMKFHSMKMEEINKIIRDLWRSTYRGQDIEYIEIRSDADENVSASDKRRNYNYRVVMLKGDTALDMRGRCSAGQKVLASLIIRLALAETFCLNCGILALDEPTTNLDRENIESLAHALVEIIKSRSQQRNFQLLVITHDEDFVELLGRSEYVEKFYRVKKNMDQCSEIVKCSISSLGSYVH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92878-1", "uniprot_id": "RAD50_HUMAN", "id": "Q92878-1", "name": "DNA repair protein RAD50", "aln": "MSRIEKMSILGVRSFGIEDKDKQIITFFSPLTILVGPNGAGKTTIIECLKYICTGDFPPGT-KGNTFVHDPKVAQETDVRAQIRLQFRDVNGELIAVQRSMVCTQKSKKTEFKTLEGVITRTKHG------EKVSLSSKCAEIDREMISSLGVSKAVLNNVIFCHQEDSNWPLSEGKALKQKFDEIFSATRYIKALETLRQVRQTQGQKVKEYQMELKYLKQYKEKACEIRDQITSKEAQLTSSKEIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNK----ESRLLNQEKSELLVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNFHKLVRERQEGEAKTANQLMNDFAEKETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNELKNVKYELQQLE--GSSDRILELDQELIKAERELSKAEKNSNVETLKMEVISLQNEKADLDRTLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSRHS-----DELTSLLGY---FPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASSEQNKNHINNELK----RKEEQLSSYEDKLFDVCGSQDFESDLDRLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEVISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLVPMRQSIIDLKEKEIPELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESAK----VCLTDVTIMERFQMELKDVERKIAQQAAKLQG-IDLDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKLNDIKEKVKNIHGYMKDIENYIQDGKDDYKKQKETELNKVIAQLSECEKHKEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRNEELKEVEEERKQHLKEMGQMQVLQMKSEHQKLEENIDNIKRNHNLALGRQKGYEEEIIHFKKELREPQFRDAEEKYREMMIVMRTTELVNKDLDIYYKTLDQAIMKFHSMKMEEINKIIRDLWRSTYRGQDIEYIEIRSDADENVSASDKRRNYNYRVVMLKGDTALDMRGRCSAGQKVLASLIIRLALAETFCLNCGIIALDEPTTNLDRENIESLAHALVEIIKSRSQQRNFQLLVITHDEDFVELLGRSEYVEKFYRIKKNIDQCSEIVKCSVSSLGFNVH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UW22-1", "uniprot_id": "A0A8N7UW22_DANRE", "id": "A0A8N7UW22-1", "name": "", "aln": "MSKIEKMSILGVRSFGVEDKDKQVISFFSPLTVLVGPNGAGKTTIIECLKYITSGDFPPGS-KGNTFVHDPKDAHETDVRAQIRLQFRDVNGDAVAVQRSMQCTQKGKKTEFKTLEGVITRIKHG------EKVSLSSKCAEIDREMISSLGVSRAVLNHVIFCHQEESNWPLSEGKALKQKFDEIFSATRYIKVLETLRTLRQKQTNTVKSCQMELKYLKQNKDKAQEIRELLSTKETQLASSKESVNRIEGQIDPLERRLNDIESSLGKVMKLDNDIKALDSRKKQMEDDNRELEEKMEQVFQGSDDQLQDMYQNHQRTVKEKEKRLVECQRELERAGR----ECQRMNRIKSELLVEQGRLQLEADRHTQNIKKRDTQVKTLASFLELEGYDRTPLSERQLQSFYRQIKERLDQDSEALNQTMHDMQQKETQKQHNIDDLRDKKTGLERTIELKKDLQAKKQQELKNIKSDLQKLE--GSSNRLQELDTELQKAERELDNAVQACTVDSLKVEVTELLKEKAQLDQAQRKLDQEMEMLNTHTTARAQMDMMKKTKMDKEEQVRKIKSRHN-----EELVSLLGH---FPNKKELEDWIYSKSREIKSTREQITKMNKELASGEQKKSHYTAEIK----RKEEQLAKYEERLFNVCGSQDFQSDLSKLEDELEKCSKQRAMLAGATAVYSQFISQLTEEGDPCCPVCQRVFPSEAELQDVINDMQSKLRLVPDKLKNTEHDLKRKERRRDEMMTLKPIRQSLVELQEKELPELRNQLQRVNRDIEKLKGDIEEQETLLCTLVSEEETAK----ACLQDISLMDRFQLDLKDVERKIAQHAAKLQG-VDLSRTMQQVSQEKQETQHRLDTTSSKIELKRKLIQDQQEQIQALRSSVNEIRGEKLQISSNMQKRQQLEEQCVEFSTEIQTLHRDIRDAKEQASPLAATLEKLQQEKQDLVERRRKKQEEGQEKINAIKEKMKNITLFEKEITKYIEEGKDSYKEQKETELQEMDKQLHEAEKQREKTNKDMGNIRQDIDTQKVQERWLQDNLTLRKRVEELKEVSRKREALIKEMGNMQVLQLRNERREVERKLEDLKKNRSVALGRQKGYEDEILRFRKELNEDQYCRAEDLYRDKMIVMRTTELANKDLDIYYKALDQTIMRFHSMKMEEINKIIRDLWRSTYRGQDIEYVEIRSDVDENASAGVKRRTYNYRVVMVKGDAALDMRGRCSAGQKVLASLIIRLALAETFCLNCGILALDEPTTNLDRENIESLAHALVEIIKSRSRQRNFQLLVITHDEDFVELLGRSNYVEHFYRIRKNQDQCSEISKCSINSLNSYLH--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W252-1", "uniprot_id": "RAD50_DROME", "id": "Q9W252-1", "name": "DNA repair protein RAD50", "aln": "MSSIESLSIQGIRSFGTYADDLQSIKFSSPVTLILGENGCGKTTVVECLKYALTGECPPGSDRGKSFVHDPKIFGLNEVLAQIKMQVRDRRGAQVSICRTMKVSKKRNKMSFETMDSTINFLTGAGQSKREKQDSLSGRSVDIDVAISDFMGVSKAIINNVLFCHQEDSSWPLDESKKLKEKFDAIFGITEYNKALDKIIKLRKEAMEELKIKEANIKHVAYLKQEMEVKTLNLQKAQRKCDAIKAQCSECEEEMKPIEARLVEIRNVEFEIGKYQAQKVEMDTKHKNCKDQISTLTLKIKKPFRGTLDELDQEISNFDQRMLEMRQKRTEVEGDLSQIKRSSVAEQEKLGTQDRKHCLAKQRHQSELACRAQLLKRVKEFCRELHIPIDCDLVEQPEKMGEVLRDIEAMIITKHCEITEIVEQNE----KADRSRQVKIDELRIELTKSEQSVTAQEKQRESSKRESETLGVEIKKIE--TSMQDLKKLEKEINEVNELYESATKNIDQQAIKDAIARKKASIAENQIQFKKLDEQLTFLGSMAKLVAECSLKQKELDKKNQEVHRVRSRHS-----DHFGKLFKEPITCNYRRSMQVVYEKLRREIQELNEKANTQKLKEQSYEIKRKNLISDIS----RMEKELKDSEELIYQKCRSTPYDDLLERSKTTISKLQFDHGALKSSEALYKKYIQKMDEE--PSCPLCHHNMTSD-EACDLTSELTDEIQKLPDNITRAEKALKAEQIKYENLLQLKPTILKVKELKDS-LPQKKEELKKVEELLGDSVSEYETLIALIGEPTHNMELAN----SMMGDMSLLDEALKDSARLTKDLDLQKGQLPASYDSSVSMDDLQAEKSKVSKELETERKELESAQNAVQQQMDALNRLREKKNSLKDRQIHLREGLQSLPQLKERLEKLNSFLTTVASEISELKAKIQPLKLNLRAAIEEKERLKKSESEKLAQLNSKYNSYKSTDHDIQRLNKEAEDYAKLDLRNEIKKLDEIIMASKDKLRKLEAEISLKTDELETIKTECSNQQTVERDLKDNRELKQLEDKEAKLRESCQVLDKQLGNLDFHSVSKEKVNLTKQRDKATVRKGELLGQLGEIHSQVNKLQREIDEPRFKESLKNFRKANYEIEVTRLCIEDLGQYRLALEWALIQFHSEKMEMINRLIREYWRKIYRGNDIDYIQVKTDEVSSDASADRRKTYNYRVVQSKNYSEIEMRGRCSAGQRVLASLIIRLALAETFSSNCGVLALDEPTTNLDRANINSLCEALNCIVEERQSQSNFMLIIITHDENFVSSLG---KITSYHRVFRNEECKSVIRRVEAGPSKKALIDQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12753-1", "uniprot_id": "RAD50_YEAST", "id": "P12753-1", "name": "DNA repair protein RAD50", "aln": "MSAIYKLSIQGIRSFDS--NDRETIEFGKPLTLIVGMNGSGKTTIIECLKYATTGDLPPNS-KGGVFIHDPKITGEKDIRAQVKLAFTSANGLNMIVTRNIQLLMKKTTTTFKTLEGQLVAINNSG-----DRSTLSTRSLELDAQVPLYLGVPKAILEYVIFCHQEDSLWPLSEPSNLKKKFDEIFQAMKFTKALDNLKSIKKDMSVDIKLLKQSVEHLKLDKDRSKAMKLNIHQLQTKIDQYNEEVSEIESQLNEITEKSDKLFKSNQDFQKILSKVENLKNTKLSISDQVKRLSNSIDILDLSKPD-LQNLLANFSKVLMDKNNQLRDLETDISSLKD--------RQSSLQSLSNSLIRRQGELEAGKETYEKNRNHLSSLKEAFQHKFQGLSNIENSDMAQVNHEMSQFKAFISQDLTDTIDQFAKDIQLKETNLSDLIKSITVDSQNLEYNKKDRSKLIHDSEELAEKLKSFKSLSTQDSLNHELENLKTYKEKLQSWESENIIPKLNQKIEEKNNEMIILENQIEKFQDRIMKTNQQADLYAKLGLIKKSINTKLDELQKITEKLQNDSRIRQVFPLTQEFQRADLEMDFQKLFINMQKNIAINNKKMHELDRRYTNALYNLNTIEKDLQDNQKSKEKVIQLLSENLPEDCTIDEYNDVLEETELSYKTALENLKMHQTTLEFNRKALEIAERD--SCCYLCSRKFENESFKSKLLQELKTKTDAN---FEKTLKDTVQNEKEYLHSLRLLEKHIITLNSINEKIDNSQKCLEKAKEETKTSKSKLDELEVDSTKLKDEKELAESEIRPLIEKFTYLEKELKDLENSSKTISEELSIYNTSEDGIQTVDELRDQQRKMNDSLRELRKTISDLQMEKDEKVRENSRMINLIKEKELTVSEIESSLTQKQNIDDSIRSKRENINDIDSRVKELEARIISLKNKKDEAQSVLDKVKNERDIQVRNKQKTVADINRLIDRFQTIYNEVVDFEAKG-FDELQTTIKELELNKAQMLELKEQLDLKSNEVNEEKRKLADSNNEEKNLKQNLELIELKSQLQHIESEISRLDVQNAEAERDKYQEESLRLRTRFEKLSSENAGKLGEMKQLQNQIDSLTHQLR-TDYKDIEKNYHKEWVELQTRSFVTDDIDVYSKALDSAIMKYHGLKMQDINRIIDELWKRTYSGTDIDTIKIRSDEVS---STVKGKSYNYRVVMYKQDVELDMRGRCSAGQKVLASIIIRLALSETFGANCGVIALDEPTTNLDEENIESLAKSLHNIINMRRHQKNFQLIVITHDEKFLGHMNAAAFTDHFFKVKRDDRQKSQIEWVDINRVTY-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * .:* *:***. .* : * * .*:*:::* **.****::***** :*: **.: :* *:**** .:: **::: . . .* : : *.: * .. *:*::. : . . .: :** :. ::* : :**.::::: *:*****:* ***.* . **:*** ** .: *.*:.: ::: :* : .:::: *:. : : : . * ::. : : .: .. : . :.. : . ..: * .:. .. : *:: *..: : : ..: : . ::. . * * : : . * :: . : .. : :: : . :: ::.:: : : : : . . : . : .::.:: : : : . :: :. .. . :: : . : .*:::.: . : :: : * * :::::: .: . .. * . .:: . ::* ..: . . . : . ::. *: : .: : : * :. * . : .. : : . : : : ..* * : : .: .: .:: : : : :: . . : * : :. : : :: *: .:. .. : . : * *: : ..: ::. : : : . . * ::::: :: : .. * . :. : ::: . : . :. . .: .: ::.: . : : : : : : .* . : : . . . :.. : . : :: .: . . : : :: : . . . ..:: : . .: *: *::* * : .: .: . . : .: : . .* .: . : . .. **. ..:: : ::: : . ::. :.. : .*:. * :*: :::::*. **: **::* : *: * * **: :::::* . : : :.****** * ::*********:****:******:*** ***::**********. **:**..:* *:: * * ** *::*****.*: :. :.:: :: * * . . ", "identical_positions": 175, "similar_positions": 452, "identity": "13.02%" }, { "cls_id": "homologset.agr.SGD:S000005195", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TSH6-1", "uniprot_id": "SCAF4_MOUSE", "id": "Q7TSH6-1", "name": "SR-related and CTD-associated factor 4", "aln": "---MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIKLYKHVVQIVEKFIKKCKPEYKVPGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKNGVFKIEIIQPLLDMAAGTSNAAPVAENVTNNEGSPPPPVKISSELA-QAPTNSMPTVAQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPQPQSPALDSAVMAQVQAITAQLKTAPTQP---------PEQKTAFDKKLLDRFDYDDEPEAVEDSKKEDAAAISTAALATAAPPAPTAATPAVATAVPVPSATSPPPPQTPFGYPGDGVQQPAYTQHQSMDQFQPRMMPIQQDTMHHQVPLPPNGQMPGFGLLSAPPPFPPMPQPGMPQP-----GMAQPGLAQPGMAQPTMPQPGMPQPGMPQPGMAQPGLAQPGMAQPGMPQPAMPQPAMPQPGMAQPGVSPAPPVQPTFQSTFQPQNEPHSQKPHQQEMEVEQPCVTEVKRHVPESRKSRSR----SPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKERERRQKGLPQIKSETASVCSTTLWVGQLDKRTTQQDVASLLEEFGPIESINMIPPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIKADYKQYWDVELGVTYIPWDKVKAEELESFCEGGMLDSDTLNPDWKGIPKKPDNEVAQNGGAETSHTEPVSPIPKPVPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGMPPPGFGPGVPPPPPPPP-FLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPN----------------------LVSGARGNAESGDSAKMYGSAGPPAAPTSLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPMMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGASEDRDGRQQQPQQQPPPQQQQQQQQPQQQ---PPQQS-------PSQQPAPAQQQPPQFRNDSRQQFNSGRDQERFGRRSFGSRVENDRERYGSRNDDRDNSNRERREWGRRSPDRDRHRDLEERSRRSSGHRDRDRDSRDRESRREKEENR-KEKHEVADRAGGNKAVEPPLSQVGTIDTVSELNKGEAMATVVKP-EESPAEVTSPVGPEKDPGSAAEPPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63627-1", "uniprot_id": "SCAF4_RAT", "id": "Q63627-1", "name": "SR-related and CTD-associated factor 4", "aln": "---MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIKLYKHVVQIVEKFIKKCKPEYKVPGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKNGVFKIEIIQPLLDMAAGTSNAAPGAENVTNNEGSPPPPVKVSSELP-QAPTNSMPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPKPQSPALDSAVMAQVQAITAQLKTAPTQP---------PEQKTAFDKKLLDRFDYDDEPEAVEDSKKEDAVAVATTALATAAPPVPAAATPAVAPAVPASSATSPPPPQAPFGYPGDGMQQPAYTQHQNVDQFQPRMMALQQDSMQHQVPLPPNGQMPGFGLLSAPPPFPPMPQPGMPQPGMPQPGMPQPGLSQPGLPQPGMPQPGMPQPGMPQPGMPQPGLPQPGLPQPGMPQPGMPQPGMPQPGMPQPGMPPTPPVQPTFQPTFQPQNEPHSQKPHQQEMEVEQPCVTEVKRHVPESRKSRSR----SPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKERERRQKGLPQIKSETASVCSTTLWVGQLDKRTTQQDVASLLEEFGPIESINMIPPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIKADFKQYWDVELGVTYIPWDKVKAEELESFCEGGMLDSDTLNPDWKGIPKKPENEVAQNGGAEASHTEPVSPIPKPVPVPVPALPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPN----------------------LVSGARGNAESADSAKMYGSAGPPAAPTSLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPMMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGSEDRDGRQQQPQQQQQQQQQQQQQQQQQQQQPPPQQSQTQQQPAPSQQPAPAQQQPQQFRNDNRQQFNSGRDQERFGRRSFGSRVENDRERYGSRSDERDNSNRERREWGRRSPERDRHRDLEERSRRSSGHRDRDRDSRDRESRREKEESRGKEKHEVADRAGGNKAVEAPLSQVGNTDTVSELNKGEAMATVVKP-EESPAEATSSVEPEKDSGSAAEAPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95104-1", "uniprot_id": "SCAF4_HUMAN", "id": "O95104-1", "name": "SR-related and CTD-associated factor 4", "aln": "---MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIKLYKHVVQIVEKFIKKCKPEYKVPGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKNGVFKIEIIQPLLDMAAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAA----APAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPP-FPPMAQP---------------------------------------------------------------------------VIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVASLLEEFGPIESINMIPPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIKADYKQYWDVELGVTYIPWDKVKPEELESFCEGGMLDSDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPP-FLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQ---QQQQP------PPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEKPEVTDRAGGNKTVEPPISQVGNVDTASELEKGVSEAAVLKPSEELPAEATSSVEPEKDSGSAAEAPR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53617-1", "uniprot_id": "NRD1_YEAST", "id": "P53617-1", "name": "Protein NRD1", "aln": "MQQDDDFQNFVATLESFKDLKSGISGSRIKKLTTYALDHIDIESKIISLIIDYSRLCPDSHKLGSLYIIDSIGRAYLDETRSNSNSS-------------------SNKPGTCAHAINTLG-------EVIQELLSDAIAKSNQD------------------------------------------------------HKEKIRMLLDIWDRSGLFQKSYLN-AIRSKCFAMDISNNTANTAS-----------QQLSLDPKQRSKQILSN--------------------------------------------LKKSPPLNLNISLPTD-------LTSTDPAKQQAALFQVIAALQKHFKTLPSHTSVG---------------------------------------------------------------------------------------------------------TVAPPQAHTITEYGSRRERERERERYNSRRNRSRSPPAPFSQ----PSTGRKDRYPSVAQDQYSIGAPNTTFGTNNHHLYPDELNVSNNPHYRPKPVSYDSTLPPDHIKVYSRTLFIGGVPLNMKEWDLANVLKPFAEVQSVILNNSRKHAFVKVYSRHEAENVLQNFNKD----GALPLRTRWGVGFGP----RDCCDYQHGYSIIPMHRLT-DADKKWSVSAQWGGTSGQPLVTGIVFEEPDIIVGEG--------------------VSSKAISQKMPTDSGRNGPRSGKPNKSGSISS--------ISPVPYGN-APLASPPPQQYVQP---MMQQPYGYAPNQPLPSQGPAAAAPPVPQ-------------------------------------------------------QQFDPTAQLNSLMNMLNQQQQQQQQS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: * * *: *:*. ** ::: :*. *:. *.: .:::.:: .: : * .:*: .**:**** * .: ::.: *:. .. .:.:* *:** **. * ..** : :::: :*: :::. *.. *: *: :: *: . :*: * . *: ::* * .: .: ..** : :. * * . : *. :: : :* .**.: .: . .* .. :: ::* * *: . :.: . . *: ... *:.* * :: . : . : . ..* . . : :. : * : . . : .: .* * **::* : . .: *:*.:*: *. ::*: : .* *:: : *::* ..**::.:. . .:: *.:. * :: * : * : ** .::. : :.:. .. .. : :* .** : : :. :* *.. .:. :.. . : *:. * *::.. :.* :* .* ..*** :::* *: * *: * * *. *..: ** **. :.. :.:*. * ", "identical_positions": 108, "similar_positions": 235, "identity": "8.71%" }, { "cls_id": "homologset.agr.SGD:S000005196", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RK00-1", "uniprot_id": "RM46_RAT", "id": "Q5RK00-1", "name": "Large ribosomal subunit protein mL46", "aln": "MAAPIGRTLLGVAKGWRQLDRLWAG--SSRGLSLEAAPSSSRSPWRLSGALCLQRPPLITKPLTPLQEEMAGLLQQVE------------VERSLYSDHELRALDE------------------AQRLAKKKADLYDEEQDQDVTLAQDLEDMWEQEFLQ-FRPGARETEADKKNDRTSLHRKLDRNLILLVREKLGDQDLWMLPQVEW-QPGETLRGTAERILATLSENNMEAKFLGNAPCGHYKFKFPKAIRTESDLGVKVFFFKALLLTGDFVQTGKKGRHVWASKEELGDYLQ-PKYLAQVRRFLLDL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQI8-1", "uniprot_id": "RM46_MOUSE", "id": "Q9EQI8-1", "name": "Large ribosomal subunit protein mL46", "aln": "MAAPVGRTLLGLARGWRQLDRFWAG--SSRGLSLEAASSSSRSPWRLSGALCLQRPPLITKALTPLQEEMAGLLQQIE------------VERSLYSDHELRALDE------------------AQRLAKKKADLYDEEQEQGITLAQDLEDMWEQAFLQ-FRPGARETEADKKNDRTSLHRKLDRNLVLLVREKLGDQDVWMLPQVEW-QPGETLRGTAERILATLSENNMEAKFLGNAPCGHYKFKFPKAIQTESDLGVKVFFFKALLLTGDFVQAGKKSRHVWASKEELGDYLQ-PKYLAQVRRFLLDSDGLSCL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2W6-1", "uniprot_id": "RM46_HUMAN", "id": "Q9H2W6-1", "name": "Large ribosomal subunit protein mL46", "aln": "MAAPVRRTLLGVAGGWRRFERLWAGSLSSRSLALAAAPSSNGSPWRLLGALCLQRPPVVSKPLTPLQEEMASLLQQIE------------IERSLYSDHELRALDE------------------NQRLAKKKADLHDEEDEQDILLAQDLEDMWEQKFLQ-FKLGARITEADEKNDRTSLNRKLDRNLVLLVREKFGDQDVWILPQAEW-QPGETLRGTAERTLATLSENNMEAKFLGNAPCGHYTFKFPQAMRTESNLGAKVFFFKALLLTGDFSQAGNKGHHVWVTKDELGDYLK-PKYLAQVRRFVSDL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W086-1", "uniprot_id": "Q9W086_DROME", "id": "Q9W086-1", "name": "Large ribosomal subunit protein mL46", "aln": "----MLRRIVQVG---------------ARELSRAQSSTASAEKWDLYAGVLVERLPVVSKSLNPLEKQFQDLLWRVE------------YENSLKSDHELKHEREI----------------VQAELIKQGKIQVDLEDAGSKQTAQDLKDAYVEELKK-FQLGSRTTPDDQANRTTSTDRCLDDTLYLLVQQKLGQQEHLILPQGKR-EEGESMRQTAERVLRESCGQELQVLFYGNAPVGFHKYKYPRNQRTET-VGAKVFFYRASLRSGQVPEN--LTKFEWLPKEALNEKLTNTAYAQSVKKFLL--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36528-1", "uniprot_id": "RM17_YEAST", "id": "P36528-1", "name": "Large ribosomal subunit protein mL46", "aln": "----MKVNLMLK-----------------RGLATATATASS-APPKIKVGVLLSRIPIIKSELNELEKKYYEYQSELEKRLMWTFPAYFYFKKGTVAEHKFLSLQKGPISKKNGIWFPRGIPDIKHGRERSTKQEVKLSDDSTVAFSNNQKEQSKDDVNRPVIPNDRITEADRSNDMKSLERQLSRTLYLLVKDKSG---TWKFPNFDLSDESKPLHVHAENELKLLSGDQIYTWSVSATPIG--VLQDERNRTAEFIVKSHILAGKFDLVAS---KNDAFEDFAWLTKGEISEYVP-KDYFNKTEFLLADN------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: * *: :.::. : .: :.* *::.. *. *::: .:* :.. ::*:: : :. . .: ::: :: : . : . . * * *. * .* .* *. .* ***::* * :*: . : .:.:: **. * . ::: . . :* * : : :* : ::: : * :. : . * .* :.: : * ... :: ", "identical_positions": 32, "similar_positions": 93, "identity": "10.06%" }, { "cls_id": "homologset.agr.SGD:S000005197", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABZ3NNN9-1", "uniprot_id": "A0ABZ3NNN9_RAT", "id": "A0ABZ3NNN9-1", "name": "THO complex subunit 3", "aln": "MPGFVVRGGREAPARSDKALLSAHARGDGARLRVSSFRRAILAERAMAVPAAVLGPSALSQSGPGSMAPWCSVSSGPSRYVLGMQELFRGHSKTREFPAHSAKVHSVAWSCDGRRLASGSFDKTASVFLLEKDRLVK-----ENNYRGHGDSVDQLCWHPSNPDLFVTASGDKTIRIWDVRTTKCIATVN------TKGENINICWSPDGQTIAVGNKDDVVTFIDAKTHRSKAEEQFKFEVN--------EISWNNDNNMFFLTNGNGCINILSYPE--LKPVQSINAHPSNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASASEDHFIDIAEVETG-------------DKLWEVQCESPTFTVAWHPKRPLLAFACDD-----------------------KDGKYDSSREAGTVKLFGLPNDS------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VE80-1", "uniprot_id": "THOC3_MOUSE", "id": "Q8VE80-1", "name": "THO complex subunit 3", "aln": "----------------------------------------------MAAPAAVLGPSALGQSGPGSMAPWCSVSSGPSRYVLGMQELFRGHSKTREFPAHSAKVHSVAWSCDGRRLASGSFDKTASVFLLEKDRLVK-----ENNYRGHGDSVDQLCWHPSNPDLFVTASGDKTIRIWDVRTTKCIATVN------TKGENINICWSPDGQTIAVGNKDDVVTFIDAKTHRSKAEEQFKFEVN--------EISWNNDNNMFFLTNGNGCINILSYPE--LKPVQSINAHPSNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASASEDHFIDIAEVETG-------------DKLWEVQCESPTFTVAWHPKRPLLAFACDD-----------------------KDGKYDSSREAGTVKLFGLPNDS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96J01-1", "uniprot_id": "THOC3_HUMAN", "id": "Q96J01-1", "name": "THO complex subunit 3", "aln": "----------------------------------------------MAVPAAAMGPSALGQSGPGSMAPWCSVSSGPSRYVLGMQELFRGHSKTREFLAHSAKVHSVAWSCDGRRLASGSFDKTASVFLLEKDRLVK-----ENNYRGHGDSVDQLCWHPSNPDLFVTASGDKTIRIWDVRTTKCIATVN------TKGENINICWSPDGQTIAVGNKDDVVTFIDAKTHRSKAEEQFKFEVN--------EISWNNDNNMFFLTNGNGCINILSYPE--LKPVQSINAHPSNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASASEDHFIDIAEVETG-------------DKLWEVQCESPTFTVAWHPKRPLLAFACDD-----------------------KDGKYDSSREAGTVKLFGLPNDS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHT2-1", "uniprot_id": "Q9VHT2_DROME", "id": "Q9VHT2-1", "name": "", "aln": "-------------------------------------------------------------------------MSRTEQTLEDLKSYLRSHSKIREQRSHMSKVHSVCWNADGRYLASGSFDKTVVVYSLERDRFLK-----GNTYRGHTASVDQLCWHRTNPDQFATASGDKTVRIWDIRVGKCVSVTN------TKGENINIAWSPDGKTIAVGNKEDLITFIDTRTNKIRVEEPFSFEVN--------EISWNNTNDLFFLTNGLGCMHILSYPS--LEHQMTLKAHPANCICIEFGPTGKYFATGSADAQVSLWDANELACLRMISRLEWPVRTISFSHDERMIALASEDLIIDIAFTETG-------------ERVTDIHVDASTFTVAWHPKQYLLAYACDE-----------------------KDN--DRRRDAGNVKIYGFSE--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53851-1", "uniprot_id": "TEX1_YEAST", "id": "P53851-1", "name": "Protein TEX1", "aln": "--------------------------------------MSTIGAVDILNQKTITSEVAASVTSKYLQSTFSKGNTSHIEDKRFIHVSSRSHSRFTSTPITPNEILSLKFHVSGSSMAYSRMDGSLTVWFIKDASFDKSVEVYIPDCCGSDKLATDLSWNPTSLNQIAVVSNSSEISLLLINEKSLTASKLRTLSLGSKTKVNTCLYDPLGNWLLAATKSEKIYLFDVKKDHSSVCSLNISDISQEDNDVVYSLAWSNGGSHIFIGFKSGYLAILKAKHGILEVCTKIKAHTGPITEIKMDPWGRNFITGSIDGNCYVWNMKSLCCELIINDLNSAVTTLDVCHLGKILGICTEDEMVYFYDLNSGNLLHSKSLANYKTDPVLKFYPDKSWYIMSGKNDTLSNHFVKNEKNLITYWKDMFDNTMIEKRRKNNGGGNNHNKRTSKNTDRIGKDRPSRFNSKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :: *.**: . :: *: : .* :* . :* : *: :: : * * . :*.*: :. : :...*... : : :. . : :* : . :.* *: : ...*.: : ::*.:..: . . ::. .::*.* .. :*: * : **. *: .::**.. *::.* *: * *** *. :*: ..* * :. *: .* *:...* :::. .:** :: : ::* : : .. : . : :: : . :. :: .. . * : ... * . ", "identical_positions": 47, "similar_positions": 132, "identity": "10.22%" }, { "cls_id": "homologset.agr.SGD:S000005199", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62633-1", "uniprot_id": "CNBP_HUMAN", "id": "P62633-1", "name": "CCHC-type zinc finger nucleic acid binding protein", "aln": "--MS-SNECFKCGRSGHWARECPTGGGRGRGMRSRGRGGFTSDRGFQFVSSSLPDICYRCGESGHLAKDCDLQED----ACYNCGRGGHIAKDCKEPKREREQCCYNCGKPGHLARDCDHADEQK------CYSCGEFGHIQKDC---------TKVKCYRCGETGHVAINCSKTSEVNCYRCGESGHLARECTIEATA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53996-1", "uniprot_id": "CNBP_MOUSE", "id": "P53996-1", "name": "CCHC-type zinc finger nucleic acid binding protein", "aln": "--MS-SNECFKCGRSGHWARECPTGGGRGRGMRSRGRGGFTSDRGFQFVSSSLPDICYRCGESGHLAKDCDLQEDE---ACYNCGRGGHIAKDCKEPKREREQCCYNCGKPGHLARDCDHADEQK------CYSCGEFGHIQKDC---------TKVKCYRCGETGHVAINCSKTSEVNCYRCGESGHLARECTIEATA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62634-1", "uniprot_id": "CNBP_RAT", "id": "P62634-1", "name": "CCHC-type zinc finger nucleic acid binding protein", "aln": "--MS-SNECFKCGRSGHWARECPTGGGRGRGMRSRGRGGFTSDRGFQFVSSSLPDICYRCGESGHLAKDCDLQED----ACYNCGRGGHIAKDCKEPKREREQCCYNCGKPGHLARDCDHADEQK------CYSCGEFGHIQKDC---------TKVKCYRCGETGHVAINCSKTSEVNCYRCGESGHLARECTIEATA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1Q6Z5-1", "uniprot_id": "F1Q6Z5_DANRE", "id": "F1Q6Z5-1", "name": "", "aln": "MDMS-TSECFGCGRSGHWIKNCPN-AGRGRG-RGRGRG---KD-----------LFCYRCGEQGHIARDCEQTED----ACYNCHRSGHISRDCKEPKKEREQCCYNCGKAGHVARDCDHANEQK------CYSCGGFGHIQKLC---------DKVKCYRCGEIGHVAVQCSKATEVNCYNCGKTGHLARDCSIEASA-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7FCQ0-1", "uniprot_id": "E7FCQ0_DANRE", "id": "E7FCQ0-1", "name": "", "aln": "--MS-SNECFGCGRTGHWIKNCPN-AGRGRG-KGRGRG---KD-----------LFCYRCGEPGHVARDCERTED----ACYNCGRGGHISRDCKEPKKEREQVCYNCGKAGHMARDCDHANEQK------CYSCGGFGHIQKGC---------EKVKCYRCGEIGHVAVQCSKASEVNCYNCGKSGHVAKECTIEATA-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M0R729-1", "uniprot_id": "M0R729_RAT", "id": "M0R729-1", "name": "", "aln": "--MS-GKSCFKCGRSGHWARECPKGGTRGRTTRGRTRGPQCSS-------ASQSDVCYRCGETGHYAKDCDLLQD----TCYNCGRRGHIAKDCTQAKREREQCCYICSRPGHLARDCDRQEEQK------CYTCGEFGHIQKDC---------TQIKCYRCGENGHMAVNCSKASEVSCYRCGESGHLARECPIEATA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WW36-1", "uniprot_id": "ZCH13_HUMAN", "id": "Q8WW36-1", "name": "Zinc finger CCHC domain-containing protein 13", "aln": "--MS-SKDFFACGHSGHWARGCPRGGAGGRRGGGHGRGSQCGS-------TTLSYTCYCCGESGRNAKNCVLLGN----ICYNCGRSGHIAKDCKDPKRERRQHCYTCGRLGHLARDCDRQKEQK------CYSCGKLGHIQKDC---------AQVKCYRCGEIGHVAINCSKARPGQLLPLRQIPTSSQGMSQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8T8R1-1", "uniprot_id": "CNBP_DROME", "id": "Q8T8R1-1", "name": "CCHC-type zinc finger nucleic acid binding protein", "aln": "--MSMSATCYKCNRPGHFARDCSLGGGGGPGGVGGGGGGGGGG--------------MRGNDGGGMRRNRE--------KCYKCNQFGHFARACP----EEAERCYRCNGIGHISKDCTQADNPT------CYRCNKTGHWVRNCPEAVNERGPTNVSCYKCNRTGHISKNCPETSK-TCYGCGKSGHLRRECDEKGGRN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53849-1", "uniprot_id": "GIS2_YEAST", "id": "P53849-1", "name": "Zinc finger protein GIS2", "aln": "--MS-QKACYVCGKIGHLAEDCDS-----------------------------ERLCYNCNKPGHVQTDCTMPRTVEFKQCYNCGETGHVRSECT------VQRCFNCNQTGHISRECPEPKKTSRFSKVSCYKCGGPNHMAKDCMK---EDGISGLKCYTCGQAGHMSRDCQ--NDRLCYNCNETGHISKDCPKA----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : *.: ** . * .. * : **:* . **. * : *: *. **::::* . .: . ** *. .* : * :.** *.. **:: :* : : ", "identical_positions": 29, "similar_positions": 33, "identity": "14.5%" }, { "cls_id": "homologset.agr.SGD:S000005201", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZU57-1", "uniprot_id": "A0A8I5ZU57_RAT", "id": "A0A8I5ZU57-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNTTSCCVSSS--PKLRRN---------------------AHSRLESYR---PDTDLSREDTGCN------------------LQHISDRENIDDLNMEFNPSDHPRASTIFLSKSQTD---VREKRKSLFINH-HPPGQTS-----------------------------------------------------------------RKYSSCSTIFLDDSTVSQPNLKYTIKCVALAIYYH------------------IKNRDPDGRMLLDIFDENLHPLSKSEVP------------------------PDYDKHNPEQKQIYRFVRTLFSAAQLTAECAIVT-------------LVYLERLLTYAEIDICPANWKR--------------------------------IVLGAILLAS-----------KVWDDQAVWN-------VDYCQILKDITVEDMNELERQFLELLQFNINVPSSVYAKYYFDLRSLAEA-----------------NSLSFPLEPLSR-------ERAHKLEAISRLCEDKY-KDLRKPMR-----KRSASADNLI--------LPRWSPAIIS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGU5-1", "uniprot_id": "CCNY_MOUSE", "id": "Q8BGU5-1", "name": "Cyclin-Y", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNTTSCCVSSS--PKLRRN---------------------AHSRLESYR---PDTDLSREDTGCN------------------LQHISDRENIDDLNMEFNPSDHPRASTIFLSKSQTD---VREKRKSLFINH-HPPGQTS-----------------------------------------------------------------RKYSSCSTIFLDDSTVSQPNLKYTIKCVALAIYYH------------------IKNRDPDGRMLLDIFDENLHPLSKSEVP------------------------PDYDKHNPEQKQIYRFVRTLFSAAQLTAECAIVT-------------LVYLERLLTYAEIDICPANWKR--------------------------------IVLGAILLAS-----------KVWDDQAVWN-------VDYCQILKDITVEDMNELERQFLELLQFNINVPSSVYAKYYFDLRSLAEA-----------------NNLSFPLEPLSR-------ERAHKLEAISRLCEDKY-KDLRKPMR-----KRSASADNLI--------LPRWSPAIIS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8ND76-1", "uniprot_id": "CCNY_HUMAN", "id": "Q8ND76-1", "name": "Cyclin-Y", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNTTSCCVSSS--PKLRRN---------------------AHSRLESYR---PDTDLSREDTGCN------------------LQHISDRENIDDLNMEFNPSDHPRASTIFLSKSQTD---VREKRKSLFINH-HPPGQIA-----------------------------------------------------------------RKYSSCSTIFLDDSTVSQPNLKYTIKCVALAIYYH------------------IKNRDPDGRMLLDIFDENLHPLSKSEVP------------------------PDYDKHNPEQKQIYRFVRTLFSAAQLTAECAIVT-------------LVYLERLLTYAEIDICPANWKR--------------------------------IVLGAILLAS-----------KVWDDQAVWN-------VDYCQILKDITVEDMNELERQFLELLQFNINVPSSVYAKYYFDLRSLAEA-----------------NNLSFPLEPLSR-------ERAHKLEAISRLCEDKY-KDLRRSAR-----KRSASADNLT--------LPRWSPAIIS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A286Y7Z8-1", "uniprot_id": "A0A286Y7Z8_DANRE", "id": "A0A286Y7Z8-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNSTSCCVSSS--PKLRRN---------------------AHSRLEPYR---PEPELSREDTGCN------------------LQHISDRENIDELNMEYNPSDHPRASTIFLSKSQTD---VREKRKSLYVNHQHPSGPMR-----------------------------------------------------------------RKYSSCSTIFLDDSTVSQPNLKYTIKCVALAIYYH------------------IKNRNVDGRMLLDIFDEKLHPLSKSEVP------------------------SDYDKHDPEQKQIYRFVRTLFSAAQLTAECAIVT-------------LVYLERLLTYAEIDICPANWKR--------------------------------IVLGAILLAS-----------KVWDDQAVWN-------VDYCQILKDITVEDMNELERQFLELLQFNINVPSSVYAKYYFDLRSLSEA-----------------NNLSFPLEPLSR-------DKAQKLEAISRLCDDKY-KDLRKAAK-----KRSVSADNLS--------VVRWSPAIIS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08CI4-1", "uniprot_id": "CCYL1_DANRE", "id": "Q08CI4-1", "name": "Cyclin-Y-like protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNTVSCCVSPSGSPKLPR----------------------QVERLEDYQ---NNTDIS-DDTGPY------------------LQHISDREVPDDLALESNPSDHARASTIFLSKSQTD---VRDRRKSNHINH-VSPGLLS-----------------------------------------------------------------KKYSSCSTIFIDDSTVSQPNLKSTIKCVTLAIYYH------------------IKNRDSDR--SLDIFDEKMHPLSREQVP------------------------DDYSRTDPEHKLIYRFVRTLFSAAQLTAECAIVT-------------LVYLERLLTYAELDICPSNWKR--------------------------------IVLGAILLAS-----------KVWDDQAVWN-------VDYCQILKDITVEDMNEMERHFLELLQFNINVPASVYAKYYFDLRSLADD-----------------NNLSFPLEPLSN-------ERAQKLEAISRLCEDKY-KDLSRVAM-----RRSFSADNLV--------GIRRSNAVLS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKF0-1", "uniprot_id": "Q9VKF0_DROME", "id": "Q9VKF0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNKNSCCAYSS--PQSDRKSKDMPPVFEERIIQLGHPPHTSQHQLDGHHGSASAVHLHHHHHGHNQQQNQQGGGGDNYENQQNLQHISERE---ALEGEEDPSVDPTAATMFLERSKVENGGMTRKRSQQQIAQQAGSGGGGGGGGGGGSTPGGN--------------------------------------------SCGGGGGMKKSSSCSTIYLDDSTVSQPNLKNTVKCVSLAIYYH------------------IKNRQSDRR--LDIFDEKLHPLTHDQVP------------------------DNYDTHNPEHRQIYKFVRTLFNAAQLTAECAIIT-------------LVYLERLLTYAELDVGPCNWKR--------------------------------MVLGAILLAS-----------KVWDDQAVWN-------VDYCQILKDITVEDMNELERQFLELLQFNINVPSSVYAKYYFDLRTLAEA-----------------NELNFPTEPLSK-------ERAQKLEAMSRVMQDKVTAEALKNGI-----KKWSSMDNISQG------GPRRSVAILS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38717-1", "uniprot_id": "SIP3_YEAST", "id": "P38717-1", "name": "Membrane-anchored lipid-binding protein SIP3", "aln": "MSVHGRDPKKRQLRLISVAFKEASIDSPSFRASVNFFQTRVDALEDWIEKTVDFFDQKYKVSFEDFRRAKETLLSQLLPPPALLSNGFVSNQSFTPRLIDSFNKDYYDFSMKLLQIVKGDDSSHSTALLELMTTAIEPYRNVRKNFDFYQGKYDSMLASYQAIRISKTSLEPSSIKSDALQLFEVQKNYLKASLDLISAISAVKLSLDKFILESMKVLKSRSIFITKDSGRKIDLSPCINEYLDNYAIWVENSIEGSKVLDSDISNAKKQAYRYTLKRITPSSDTSDYNIRSIHSSKLLSKDTQVPPKSPEKSGWLYMKTQVGKPTREIWVRRWCFLKNAVFGMFLLSPSKTYVEETDKFGVFLTNVRYDPEEDRKFCFEVKIFGNKVTEAHDNMSKDITLVFQTSNYLDLKSWLIAFEATKKYVMSIQHDSLEYELAFKRFSPKFFEFASSTTTSIDQLITTFDKETESLYETLNCSISEYDILTLGEEKVFQFQMPTTPISTKMTQLAILSNFLTKGSWFPNAVLANIWGTTDWSEYTILPGKGKKPSSLLTIDGKRLPIRNSTIYPQYYSNELKVLDLQFKSLVFSPDQRLEKLPEELLLFKFEALWCPNKKQKFSATCFCTKDYIYCYMNSMEFICLTKISLSEIVSVEADRSSKKTLKLYDASGLQMKAIVLFSDYKLIASKLQYLLENKAIKNPNSNEEILVKFEQMEKESQEKKQEELYKIEQENSFDRKATSVSKIIKSRVTFWEMSDDASTLLNRLKKLQTEYSITYNHEYEISSKGLAHILFGDKSNAFPKCLFLARKDGEEHGKRFWYKNKDINGKSQLVRKIPFRLDMTGNFLNTGKYHRDKESKMIFATQRIVKIVDNKYYEVDLDPFFVKVPFCHLLKLSIKFVITESYDVDNHLEIKLNMTASSSSLHVLYKLEYIDSRTGKTIEKLSLAEIICQTWALKFAHSEFLLIRRVLRYYLEKIGKHGKVIKAIKLCGILGVLSNKSEEPATEKNGNSKESESMQYDIRYSCTILFLVFIKLMVYRVTNLTFVFFRILIGILLLCAEKFSRINRMMVVGLLASIMINILLSEKASVPYWSIKRAEKLFHDRLGSDKFTMQRAIYISDSDLLSSQLSVPSNNPIFEKFSEDNFNKDYQYSETRKQLAMRRNELLIELRILQDMEKQLVHDDYEKFLLEEVNKCSMVSIEMTDLWFNDTQLQNYCSICNEELEKLRPPIT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ... .. *: : : .. * : *. : : . . : . : *... : :.. : : :* . .*: :. * :: *:. :. * : * *:: . : :. *. ::. :: . .. :*. .. :::* . : :: **:: *. : ::* : * : *: : : :::::. ::. :*:* * ** **.:* * :.:. *. .. . *: ..*.: * : : *:* :.: ::* : : :: * .:: : :::. ", "identical_positions": 37, "similar_positions": 125, "identity": "3.01%" }, { "cls_id": "homologset.agr.SGD:S000005202", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V8C2-1", "uniprot_id": "ZW10_RAT", "id": "Q4V8C2-1", "name": "Centromere/kinetochore protein zw10 homolog", "aln": "------MASFVTEVLAHSG--SLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPTMQSAQALVTQVDTLSNDIDQLKSRIETEVCRDLHISTVEFTNLKQRLERDSVVLNLLKQLQE-FSSAIEEYNSALAEKKYIPAAR-LLEEAQECLKLLKSKKCFDLKMLKSLSMELTVQKQNILYHLGEDWQKLVVWKFPPSKDTSSLESCLQTELHLCTEQPEKE-MTPLPSISSVLLAFSILGELPTKLKS---FGQMLLKYILKPLVTCP--SLHAVIERQPNSVSICFQSLATDSEHPPPPEAFAKIQLVLEVLQKQLLDLPLDADLEIGKVPEIVLAEMLGEVIWEDLSDCLIRNCLVYSIPTNSSKLQQYEEIIQSTEEFEKSLKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVAARHLMTSEIHNTVKIGPDCEETLPDLPSPDADHRLQVQ-VCKVQFTDAGNLEPETSLDPRSFSLPTCRISEAVKKLMELAYQTLLEATTSS-DQCAVQLFYSVRNIFHLFHDVVPTYHKENLQKLPQLAAIHHNNCMYIAHHLLTLGHQFRSRLTPI--LCDGTTTFVDLVPGFRRLGTECFLAQMRTQKGELLERLSSARSFANMDDEENYSAASKAVRQVLHQLKRLGIVWQDVLPVNIYCKAMGTLLNTVIAEMIGRITALEDISTEDGDRLYSLCKTVMDEGPQVFAPLSDENKNKKYQEEVPVYVSKWMPFKELMIMLQASLQEIGDRWADGKGPLATAFPSSEVKALIRALFQNTERRAAALAKIK---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54692-1", "uniprot_id": "ZW10_MOUSE", "id": "O54692-1", "name": "Centromere/kinetochore protein zw10 homolog", "aln": "------MASFVTEVLAHSG--SLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPTMQSAQALVTQVDTLSNDIDQLKSRIETEVCRDLHISTVEFTNLKQQLERDSVVLTLLKQLQE-FSSAIEEYNSALAEKKYIPAAR-HLEEAQECLKLLKSRKCFDLKMLKSLSMELTVQKQNILYHLGEDWQKLVVWKFPPAKDTSSLESCLQTELHLCTEQPEKEDMTPLPSISSVLLAFSILGELPTKLKS---FGQMLLKYILKPLVTCP--SLHAVIERQPSSVSICFESLTTDLEHPSPPEAFAKIRLVLEVLQKQLLDLPLDADLEIGKVPGIVLAEMLGEGIWEDLSECLIRNCLVYSIPTNSSKLQEYEEIIQSTEEFEKFLKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVAARNLMTSEIHNTVKIGPDCKEALPDLPSPDADHKLQVQTVCKAQFTDAGNLEPETSLDPQSFSLPTCRISEAVKKLMELAYQTLLEATTSS-DQCAVQLFYSVRNIFHLFHDVVPTYHKENLRKLPQLAAIHHNNCMYIAHHLLTLGHQFRLRLAPI--LCDGTTTFVDLVPGFRRLGTECFLAQMQAQKGELLERLSSARSFANMDDEENYSAASKAVRQVLHQLRRLGIVWQDVLPVNIYCKAMGTLLNTAIAEMMSRITALEDISTEDGDRLYSLCKTVMDEGPQVFAPLSDENKNKKYQEEVPVYVSKWMPFKELMIMLQASLQEIGDRWADGKGPLATAFPSSEVKALIRALFQNTERRAAALAKIK---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43264-1", "uniprot_id": "ZW10_HUMAN", "id": "O43264-1", "name": "Centromere/kinetochore protein zw10 homolog", "aln": "------MASFVTEVLAHSG--RLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDIDLLKSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQE-FSTAIEEYNCALTEKKYVTGAQ-RLEEAQKCLKLLKSRKCFDLKILKSLSMELTIQKQNILYHLGEEWQKLIVWKFPPSKDTSSLESYLQTELHLYTEQSHKEEKTPMPPISSVLLAFSVLGELHSKLKS---FGQMLLKYILRPLASCP--SLHAVIESQPNIVIIRFESIMTNLEYPSPSEVFTKIRLVLEVLQKQLLDLPLDTDLENEKTSTVPLAEMLGDMIWEDLSECLIKNCLVYSIPTNSSKLQQYEEIIQSTEEFENALKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVAARNLMTSEIHNTVKIIPDSKINVPELPTPDEDNKLEVQKVSNTQYHEVMNLEPENTLDQHSFSLPTCRISESVKKLMELAYQTLLEATTSS-DQCAVQLFYSVRNIFHLFHDVVPTYHKENLQKLPQLAAIHHNNCMYIAHHLLTLGHQFRLRLAPI--LCDGTATFVDLVPGFRRLGTECFLAQMRAQKGELLERLSSARNFSNMDDEENYSAASKAVRQVLHQLKRLGIVWQDVLPVNIYCKAMGTLLNTAISEVIGKITALEDISTEDGDRLYSLCKTVMDEGPQVFAPLSEESKNKKYQEEVPVYVPKWMPFKELMMMLQASLQEIGDRWADGKGPLAAAFSSSEVKALIRALFQNTERRAAALAKIK---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4X9-1", "uniprot_id": "ZW10_DROME", "id": "Q9W4X9-1", "name": "Centromere/kinetochore protein zw10", "aln": "MEEEAPRFNVLEEAFNGNGNGCANVEATQSAILKVLTRVNRFQMRVRKHIEDNYTEFLPNNTSPDIFLEESGSLNREIHDMLENLGSEGLDALDEANVKMAGNGRQLREILLGLGVSEHVLR-IDELFQCVEEAKATKDYLVLLD-LVGRLRAFIYGDDS--------VDGDAQVATPEVRRIFKALECYETIKVKYHVQAYMLQQSLQERFDRLVQLQCKSFPTSRCVTLQVSRDQTQLQDIVQALFQEPYNPARLCEFLLDNCIEPVIMRP--VMADYSEEADGGTYVRLS-LSYATKEPSSAHVRPNYKQVLENLRLLLHTL---AGINCSVSRDQHVFGIIGDHVKDKMLKLLVDECLIPAVPESTEEYQTSTLCEDVAQLEQLLVDSFIINPEQDRALGQFVEKYETYYRNRMYRRVLETAREIIQRDLQDMVLVAPN-------------------------------NHSAEVANDP--FLFPRCMISKSAQDFVKLMDRILRQPTDKLGDQEADPIAGVISIMLHTYINEVPKVHRKLLESIPQQAVLFHNNCMFFTHWVAQHAN-------------KGIESLAALAKTLQATGQQHFRVQVDYQSSILMG---IMQEFEFESTHTLGSGPLKLVRQCLRQLELLKNVWANVLPETVYNATFCELINTFVAELIRRVFTLRDISAQMACELSDLIDVVLQRAPTLFREPNE-----------VVQVLSWLKLQQLKAMLNASLMEITELWGDGVGPLTASYKSDEIKHLIRALFQDTDWRAKAITQIV---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53847-1", "uniprot_id": "DSL1_YEAST", "id": "P53847-1", "name": "Protein transport protein DSL1", "aln": "----------MESLFPNKG------EIIRELLKDPLILKNDSKRSNGSELELDSSDLLQREAILANELNILDNLKTFLNLIKEVKTNLNILELENCYYSLQSLRKKMRNNAAYLKQSFNFQQSISTYVDTLHLELVSTLYKILTNGFWKITENSIQFTPTVEWGKDKVHIEYDTFMDFVAQQYFPKGSLDNQAWFILDMTSADSQEQVRAKLNTIMKEYMNLSRIVSMIKNSIFISGKEISYENEKNILVFSKSSSHGQHCVSTVLTSFEAVCDFMLDGLAFRDRKTLSYELGPLFNTEFTKFVKNNASIILESLDSPLKNLVSVINNKLTRLVAKSEVTNWTHSGKEIQDLLMNKQLYYNLLLDKVLES-HISEIRSIFEDPKKSWQNLEVVELTTSNTNTMSEKIGKNDSDVQNEKELHNAVSKDDDWNWEVEDDDADAWGDEIDVN---------------IDDEEEKTNQEKEKEPEEEENAWDEAWAIDENIDDASLENGKEHLKAHDVGSLDKDHIEVTQLPKLFLAISQNFKSSFADSHVDEQYFAYKYNLLQTSYMAMCTANFSHNWCQLYVDMRYLIERDEKLYRIKELTRNLLETKLNMKYRIVCQLIRHQLTEFRENE--RNPSWDATIEKLLPYILKEIVRPLQKIRGEEGSRYLLSFLNFLYNDCVTKEILKWQIISEVNSENLGELVSLLVNNTDIQLLAKE---------------PSYKKMREKFATMGKFLPLHLKEIMEMFYNG---DFYLFATDELIQWIELLFADTPLRRNAIDDIYEIRGTALDD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : .* * : : : . :. . :::* : ..*. :. : . . *. . .: . :::.. * :. . :. .: . . . * . : : :. : . .. . ..:. :: :: : . . : :. : .. : : : . . *: * : . *. : : : . : *: .: . . : .: :. . : : : : : :: *. : . ::.: . : . * : : . . .: . :: . * *: : :: : .. . : . : ::: .: . .: : : : : : :. : * : *::: . : * * ::: : : : ::.:: .* .* : : : :* * ** : : :* : :.*: *. ** :* * *: .* ", "identical_positions": 34, "similar_positions": 183, "identity": "4.22%" }, { "cls_id": "homologset.agr.SGD:S000005203", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUC4-1", "uniprot_id": "ATOX1_RAT", "id": "Q9WUC4-1", "name": "Copper transport protein ATOX1", "aln": "---MPKHEFSVDMTCGGCAEAVSRVLNKLGG--VEFNIDLPNKKVCIESEHSSDILLATLNKTGKAVSYLGPK-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08997-1", "uniprot_id": "ATOX1_MOUSE", "id": "O08997-1", "name": "Copper transport protein ATOX1", "aln": "---MPKHEFSVDMTCEGCAEAVSRVLNKLGG--VEFNIDLPNKKVCIDSEHSSDTLLATLNKTGKAVSYLGPK-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00244-1", "uniprot_id": "ATOX1_HUMAN", "id": "O00244-1", "name": "Copper transport protein ATOX1", "aln": "---MPKHEFSVDMTCGGCAEAVSRVLNKLGG--VKYDIDLPNKKVCIESEHSMDTLLATLKKTGKTVSYLGLE-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PD88-1", "uniprot_id": "M9PD88_DROME", "id": "M9PD88-1", "name": "Copper transport protein ATOX1", "aln": "---MTVHEFKVEMTCGGCASAVERVLGKLGDKVEKVNINLEDRTVSVTSNLSSDELMEQLRKTGKSTTYVGVKKXDEFLSKFQKYGRLKLEV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38636-1", "uniprot_id": "ATX1_YEAST", "id": "P38636-1", "name": "Copper chaperone ATX1", "aln": "MAEIKHYQFNVVMTCSGCSGAVNKVLTKLEPDVSKIDISLEKQLVDVYTTLPYDFILEKIKKTGKEVR-SGKQL------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::*.* *** **: **.:** ** : :*.* .: * : : . * :: :.**** . * : ", "identical_positions": 22, "similar_positions": 21, "identity": "23.91%" }, { "cls_id": "homologset.agr.SGD:S000005205", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K6D6-1", "uniprot_id": "A0A0G2K6D6_RAT", "id": "A0A0G2K6D6-1", "name": "Origin recognition complex subunit 5", "aln": "----MSHLESMVLCREAQVSTLQSLFGEREHFSFPSIFIYGHTASGKTYVTQTLLKTL----ELPHAFVNCVECFTSRLLLEQILNKLSH-----LSSSEAECSTETTCETFNDFVRLFKQVTSAEH--LKDQTVYIVLDKADYLRDMEANLLPGFLRLQELTDRN--VTVIFLSEIIWEKFRPNTGCFEPFVLHFPDYSIGNLQKILSHDHP---------------------PGYSADFYSAYINILLGVFYTVCRDLKELRHLAVLNFPKYCEPVVKGEAGERDTRKLWRNIEPHLKKAMQTVYLREVSSSQWETLQKDATDLGQLKGLSAYTHVELPYYSKFILIAAYLASYNPARTDRRFFLKHHGKIKK----TNFLKKHEKTSNHLLGPKPFPLDRLLAILYSIVDSRVAPTANIFSQVFVSVCFTSNTALDKDNLRGPDCVCSFLLFCGDVCNYSENRTALKNIARTCSESEYWVSLKITSLVTLQLLTVV--GHEDQLNG-PKYKCTVSLDFIRSIARTVNFDIIKYLYDFL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUV0-1", "uniprot_id": "ORC5_MOUSE", "id": "Q9WUV0-1", "name": "Origin recognition complex subunit 5", "aln": "----MSHLESMVLCREAQVSTLQSLFGERHHFSFPSIFIYGHTASGKTYVTQTLLKTL----ELPHAFVNCVECFTSRLLLEQILNKLSH-----LNSSDAGCSTEMTCETFNDFVQLFKQVTSAEH--LKDQTVYIVLDKAEYLRDMEANLLPGLLRLQELTDRN--VTVIFLSEIIWEKFRPNTGCFEPFVLYFPDYSIGNLQKILSHDHP---------------------PEYSADFYAAYINILLGVFYTVCRDLKELRHLAVLNFPKYCEPVVKGEAGERDTRKLWRNIEPHLKKAMQTVYLREISSSQWEKLQKDNTDPGQLKGLSAYTHMELPYYSKFILIAAYLASYNPARTDKRFFLKHHGKIKK----TNFLKKHEKTSNHLLGPKPFPLDRLLAILYSIVDSRVAPTANIFS-------------------------------------------------------------QITSLVTLQLLTIV--GHEDQLNG-PKYKCTVSLDFIRAIARMVNFDIIKYLYDFL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43913-1", "uniprot_id": "ORC5_HUMAN", "id": "O43913-1", "name": "Origin recognition complex subunit 5", "aln": "----MPHLENVVLCRESQVSILQSLFGERHHFSFPSIFIYGHTASGKTYVTQTLLKTL----ELPHVFVNCVECFTLRLLLEQILNKLNH-----LSSSEDGCSTEITCETFNDFVRLFKQVTTAEN--LKDQTVYIVLDKAEYLRDMEANLLPGFLRLQELADRN--VTVLFLSEIVWEKFRPNTGCFEPFVLYFPDYSIGNLQKILSHDHP---------------------PEYSADFYAAYINILLGVFYTVCRDLKELRHLAVLNFPKYCEPVVKGEASERDTRKLWRNIEPHLKKAMQTVYLREISSSQWEKLQKDDTDPGQLKGLSAHTHVELPYYSKFILIAAYLASYNPARTDKRFFLKHHGKIKK----TNFLKKHEKTSNHLLGPKPFPLDRLLAILYSIVDSRVAPTANIFS-------------------------------------------------------------QITSLVTLQLLTLV--GHDDQLDG-PKYKCTVSLDFIRAIARTVNFDIIKYLYDFL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24169-1", "uniprot_id": "ORC5_DROME", "id": "Q24169-1", "name": "Origin recognition complex subunit 5", "aln": "MEAICSSLEPLFPCREAAIETLGELIGDSSETYPSAIYLFGHSGTGKTALTRAFLKECGKRQNVRTAHLNAIECYTTKIMLEILLDSLAP-----DQGD------ALKVDNMLDFVEQLRR-QAATR--VEDQGFLIAVDNAERLRDMDANVLPVLLRLQELTNLN--LCVILLSQLPFEKFYNKTGLSEIVCLHLAQYNKAETQRILGSDFQQVRNQLLEQFAQDKKRLEICQEAVTEDFYNNYLNLFLSVFYKACRDVPELQLTARKCLSTYLEPVLDGTVDATDISRLWRHIAGPLRSALTQIYMR-IEKPAEEVEDFTAIEDQSVRKLAQS--LELPYYAKFLLIAAFLASHNAAKQDKRLFVKHHGKQRKRMQTVNARAKTTEKMSTTLGPKSFSIDRLLAIFYAILEEKVGLTCNLLS-------------------------------------------------------------QISTLVHLNLLSFVS-GEQNIMEGSARLQCTIGLEFVLQIGKVVGFNVRQYLCDFM-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50874-1", "uniprot_id": "ORC5_YEAST", "id": "P50874-1", "name": "Origin recognition complex subunit 5", "aln": "----MNVTTPEVAFREYQTNCLASYISADPDITPSNLILQGYSGTGKTYTLKKYFNAN---PNLHAVWLEPVELVSWKPLLQAIARTVQYKLKTLYPNIPTTDYDPLQVEEPFLLVKTLHNIFVQYESLQEKTCLFLILDGFDSLQDLDAALFNKYIKLNELLPKDSKINIKFIYTMLETSFLQRYSTHCIPTVMFPRYNVDEVSTILVMSRCG------ELMEDSCLRKRIIEEQITDCTDDQFQNVAANFIHLIVQAFHSYTGNDIFALNDLIDFKWPKYVSRITKENIFEPLA--LYKSAIKLFLSTDDNLSENGQGESAITTN-RDDLENSQTYDLSIISKYLLIASYICSYLEPRYDASIFSRKTRIIQG--RAAYGRRKKKEVNPRYLQPSLFAIERLLAIFQAIFPIQGKAESGSLSALREESLMKAN---------------------------------------------IEVFQNLSELHTLKLIATTMNKNIDYLSPKVRWKVNVPWEIIKEISESVHFNISDYFSDIHE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ** . * . :. . . : : *::.:*** : :: :: . :: :* : : :*: : .: . : :*. ::. . :. . : :* : *:*::* :: ::*:** : : : :: : .* . . : :. *. : . ** . : : *: ..:: : . . : : .. .::. : * .: ::: .. : * :*. :*::***:::.*: .: * :* :: : . * : * *. *.::*****: :*. : .. :* ::: * *:*:: . . : :. : : .: ::: *.. * *:: .*: *: ", "identical_positions": 51, "similar_positions": 148, "identity": "9.41%" }, { "cls_id": "homologset.agr.SGD:S000005206", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8X4-1", "uniprot_id": "D3Z8X4_RAT", "id": "D3Z8X4-1", "name": "DNA polymerase epsilon catalytic subunit", "aln": "-MVLRNSGRRHPEPGADSEGSRDDGPSS-SVSALKRLERSQWTDKMDLRFGFERLKEPGE--------------RTGWLINMHPTEILDE-------------------DKRLVSAVDYYFIQDDGSRFKVALPYKPYFYIAARKGCDR-EVSSFLSKKFQGKIAKLENVPKEDLDLPNHLVGLKRSYIKLSFHTVEDLVKVRKEISPAVKKNREQDHASDEYTTMLSSILQGGSLITDEEETSKKIADQLDNIVDMREYDVPYHIRLSIDLRIHVAHWYNVRFRGNAFPVEIARRDDLVERPDPVVLAFDIETTKLPLKFPDAETDQIMMISYMIDGQGYLITNREIVSEDIEDFEFTPKPEYEGPFCVFNEPDEVHLIQRWFEHIQETKPTIMVTYNGDFFDWPFVEARAAIHGLSMYQEIGFQKDSQGEYKAPQCIHMDCLRWVKRDSYLPVGSHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDAVATYYLYMKYVHPFIFALCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQEFNKLTDDGHVLDAETYVGGHVEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTMRHAIEEEEKVPVEQATNFQEVCEQIKTKLTSLKDVPNRIECPLIYHLDVGAMYPNIILTNRLQPSAIVDEATCAACDFNKPGATCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPP--LFPEGPARAFHELSREEQAKYEKRRLADYCRKAYKKIHMTKVEERLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLSAAVEVGDASEVKRCKNMEILYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGANIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVIKTTNVKKPKLTISYPGAMLNIMVKEGFTNHQYQELTEPSS---LTYVTRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFNEDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVYASVAKVADYWLDVLYSKAANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYIISRKPEGSPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQDFDIRTILDWDYYIERLGSAIQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDIYKQKKISELFVLEGKRQIVMAQASENSLSLCTPDMEDFGLTKPYHSTV--PVATKRKR-VWESQKESQDITLTVPWQEVLGQPPSLGTTQEEWLVWLQFHKKKWQLQAQQRLARRKKQRLESAEDMPRLGAIREGPATGLGSFLRRTARSIMDLPWQIIQISETRQAGLFRLWAIIGSDLHCIKLSIPRVFYVNQR-VAKAEDGPS---YRKVNRALPRSNIVYN-----LYEYSVPEDMYQEHINEINTELSAPDIEGVYETQVPLLFRALVQLGCVCVVNKQLAR---QLSGWEAETFALEHLEMRSLAQFSYLEPGS--IRHIYLYHH--TQGHKALFGVFIPSQRRASVFVLDTVRSNQMP---GLSALYSAEHSLLLDKVGP---NLLPPPKHTFEVRAETNLKTICRAIQRFLLAYKEERRGPTLIAIQSSWELCRLTSEIPVLEEFPLVPVRVADKIS-YAVLDWQRHGARRMIRHYLNLDICLSQAFEMSRYFHIPVGNLPEDISTFGSDLFFARHLQRHNHLLWLSPTS-RPDLGGKEAD-DNRLVMEFDDRATVEINNSGCYSTVCVELDIQNLAVNTILQSHHVNDMEGAGSMGISFDVIQQASLEDMVTGNQAASALASYDETALCSSTFRILKSMVVGWVKEITQYHNIYADNQVMHFYRWLQSPCSLLHDPALHRTLHNMMKKLFLQLIAEFKRLGSSVIYANFNRIILCTKKRRIEDALAYVEYITNSIHSKEIFHSLTISFSRCWEFLLWMDPSNYGGIKGKVP-------SSIHCGQVREQDSQTREETEDEEDNEK--DEEEEEDMGQSEVEDL-LENNWNILQFLPQAASCQSYFLMIVSAYIVAVYQSMKDELRHSAPGSTPVKRKGASQFSQEAEGAAGALPGMITFSQDYVANELTQTFFTITQKIQKKVT--GSRNTAEPSEMFPVLPGSHLLLNNPALEFIKYVCKVLSLDTNITNQVNKLNRDLLRLVDVGEFSEEAQFRDPCHSYVLPEVICHSCNFCRDLDLCKDSSFSQDGAILPQWLCSNCQAPYDSSAIESALVEALQRKLMAFTLQDLVCLKCRGMKETHMPVYCGCAGDFVLTIHTEVFMEQIRIFQNIAKYYNMSYLQEAIEWLLQTSPVSNF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVF7-1", "uniprot_id": "DPOE1_MOUSE", "id": "Q9WVF7-1", "name": "DNA polymerase epsilon catalytic subunit A", "aln": "-MVLRNSGRRHPEPGADGEGSRDDGPSS-SVSALKRLERSQWTDKMDLRFGFERLKEPGE--------------RTGWLINMHPTEILDE-------------------DKRLVSAVDYYFIQDDGSRFKVALPYMPYFYIAARKGCDR-EVSSFLSKKFQGKIAKLENVPKEDLDLPNHLVGLKRSYIKLSFHTVEDLVKVRKEISPAVKKNREQDHASDEYTTMLSSILQGGSVITDEDETSKKIADQLDNIVDMREYDVPYHIRLSIDLRIHVAHWYNVRFRGNAFPVEITRRDDLVERPDPVVLAFDIETTKLPLKFPDAETDQIMMISYMIDGQGYLITNREIVSEDIEDFEFTPKPEYEGPFCVFNEPDEVHLIQRWFEHIQETKPTIMVTYNGDFFDWPFVEARAAIHGLSMYQEIGFQKDSQGEYKAPQCIHMDCLRWVKRDSYLPVGSHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDAVATYYLYMKYVHPFIFALCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQEFNKLTDDGHMLDAETYVGGHVEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTMRHAIEEEEKVPVEQATNFQEVCEQIKTKLTSLKDVPNRIECPLIYHLDVGAMYPNIILTNRLQPSAIVDEATCAACDFNKPGASCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPP--LFPEGPARAFHELSREEQAKYEKRRLADYCRKAYKKIHVTKVEERLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLSAAVEVGDASEVKRCKNMEILYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGANIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVIKTTNAKKPKLTISYPGAMLNIMVKEGFTNHQYQELTEPSS---LTYVTHSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFNEDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDVLYSKAANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYIISRKPEGSPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQDFDIRTILDWDYYIERLGSAIQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDIYKQKKISELFVLEGKRQIVMAQASENSLSLCTPDMEDIGLTKPHHSTV--PVATKRKR-VWETQKESQDIALTVPWQEVLGQPPSLGTTQEEWLVWLQFHKKKWQLQAQQRLALRKKQRLESAEDMPRLGPIREGPSTGLGSFLRRTARSIMDLPWQIIQISETRQAGLFRLWAIIGNDLHCIKLSIPRVFYVNQR-VAKAEDGPA---YRKVNRALPRSNIVYN-----LYEYSVPEDMYQEHINEINTELSVPDIEGVYETQVPLLFRALVQLGCVCVVNKQLTR---HLSGWEAETFALEHLEMRSLAQFSYLEPGS--IRHIYLYHH--TQGHKALFGVFIPSQRRASVFVLDTVRSNQMP---GLSALYSSEHSLLLDKVDP---KLLPPPKHTFEVRAETNLKTICRAIQRFLLAYKEERRGPTLIAVQSSWELCRLTSEIPVLEEFPLVPIRVADKIS-YAVLDWQRHGARRMIRHYLNLDLCLSQAFEMSRYFHIPVGNLPEDISTFGSDLFFARHLQHHNHLLWLSPTS-RPDLGGKEAD-DNRLVMEFDDRATVEINSSGCYSTVCVELDIQNLAVNTILQSHHVNDMEGAGSMGISFDVIQQASLEDMVTGNQAASALANYDETALCSSTFRILKSMVVGWVKEITQYHNIYADNQVMHFYRWLQSPCSLLHDPALHRTLHNMMKKLFLQLIAEFKRLGSSVVYANFNRIILCTKKRRIEDALAYVEYITNSIHSKEIFHSLTISFSRCWEFLLWMDPSNYGGIKGKVP-------SSIHCGQVKEQDSQAREETDEEEEDKE--KDEEEEGMGESEVEDL-LENNWNILQFLPQAASCQSYFLMIVSAYIVAVYQSMKEELRHSAPGSTPVKRKGASQFSQESEGATGSLPGMITFSQDYVANELTQSFFTITQKIQKKVT--GSRNTTEPSEMFPVLPGSHLLLNNPALEFIKYVCKVLSLDTNITNQVNKLNRDLLRLVDVGEFSEEAQFRDPCHSYVLPEVICHSCNFCRDLDLCKDSSFSQDGAILPQWLCSNCQAPYDSSAIESALVEALQRKLMAFTLQDLVCLKCRGMKETHMPVYCSCAGDFTLTIRTEVFMEQIRIFQNIAKYYSMSYLQETIEWLLQTSPVSNC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07864-1", "uniprot_id": "DPOE1_HUMAN", "id": "Q07864-1", "name": "DNA polymerase epsilon catalytic subunit A", "aln": "-MSLRSGGRRRADPGADGEASRDDGATS-SVSALKRLERSQWTDKMDLRFGFERLKEPGE--------------KTGWLINMHPTEILDE-------------------DKRLGSAVDYYFIQDDGSRFKVALPYKPYFYIATRKGCER-EVSSFLSKKFQGKIAKVETVPKEDLDLPNHLVGLKRNYIRLSFHTVEDLVKVRKEISPAVKKNREQDHASDAYTALLSSVLQRGGVITDEEETSKKIADQLDNIVDMREYDVPYHIRLSIDLKIHVAHWYNVRYRGNAFPVEITRRDDLVERPDPVVLAFDIETTKLPLKFPDAETDQIMMISYMIDGQGYLITNREIVSEDIEDFEFTPKPEYEGPFCVFNEPDEAHLIQRWFEHVQETKPTIMVTYNGDFFDWPFVEARAAVHGLSMQQEIGFQKDSQGEYKAPQCIHMDCLRWVKRDSYLPVGSHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDAVATYYLYMKYVHPFIFALCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQEFNKLTDDGHVLDSETYVGGHVEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTLRHALEEEEKVPVEQVTNFEEVCDEIKSKLASLKDVPSRIECPLIYHLDVGAMYPNIILTNRLQPSAMVDEATCAACDFNKPGANCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPP--LFPEGPARAFHELSREEQAKYEKRRLADYCRKAYKKIHITKVEERLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLSAAVEVGDAAEVKRCKNMEVLYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGANIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVFKTTNVKKPKVTISYPGAMLNIMVKEGFTNDQYQELAEPSS---LTYVTRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFNEDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDVLYSKAANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYIISRKPEGSPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQDFDIRAILDWDYYIERLGSAIQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDVYKQKKISELFTLEGRRQVTMAEASEDSPRPSAPDMEDFGLVKLPHPAA--PVTVKRKRVLWESQEESQDLTPTVPWQEILGQPPALGTSQEEWLVWLRFHKKKWQLQARQRLARRKRQRLESAEGVLRPGAIRDGPATGLGSFLRRTARSILDLPWQIVQISETSQAGLFRLWALVGSDLHCIRLSIPRVFYVNQR-VAKAEEGAS---YRKVNRVLPRSNMVYN-----LYEYSVPEDMYQEHINEINAELSAPDIEGVYETQVPLLFRALVHLGCVCVVNKQLVR---HLSGWEAETFALEHLEMRSLAQFSYLEPGS--IRHIYLYHH--AQAHKALFGIFIPSQRRASVFVLDTVRSNQMP---SLGALYSAEHGLLLEKVGP---ELLPPPKHTFEVRAETDLKTICRAIQRFLLAYKEERRGPTLIAVQSSWELKRLASEIPVLEEFPLVPICVADKIN-YGVLDWQRHGARRMIRHYLNLDTCLSQAFEMSRYFHIPIGNLPEDISTFGSDLFFARHLQRHNHLLWLSPTA-RPDLGGKEAD-DNCLVMEFDDQATVEINSSGCYSTVCVELDLQNLAVNTILQSHHVNDMEGADSMGISFDVIQQASLEDMITGGQAASAPASYDETALCSNTFRILKSMVVGWVKEITQYHNIYADNQVMHFYRWLRSPSSLLHDPALHRTLHNMMKKLFLQLIAEFKRLGSSVIYANFNRIILCTKKRRVEDAIAYVEYITSSIHSKETFHSLTISFSRCWEFLLWMDPSNYGGIKGKVS-------SRIHCGLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVEDL-LENNWNILQFLPQAASCQNYFLMIVSAYIVAVYHCMKDGLRRSAPGSTPVRRRGASQLSQEAEGAVGALPGMITFSQDYVANELTQSFFTITQKIQKKVT--GSRNSTELSEMFPVLPGSHLLLNNPALEFIKYVCKVLSLDTNITNQVNKLNRDLLRLVDVGEFSEEAQFRDPCRSYVLPEVICRSCNFCRDLDLCKDSSFSEDGAVLPQWLCSNCQAPYDSSAIEMTLVEVLQKKLMAFTLQDLVCLKCRGVKETSMPVYCSCAGDFALTIHTQVFMEQIGIFRNIAQHYGMSYLLETLEWLLQKNPQLGH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VCN1-1", "uniprot_id": "DPOE1_DROME", "id": "Q9VCN1-1", "name": "DNA polymerase epsilon catalytic subunit 1", "aln": "-MSDSSKGKVLQNTGKFVSENRTEGDDF-FNEAGYRQSRE--NDKIDSKYGFDRVKDSQE--------------RTGYLINMHSNEVLDE-------------------DRRLIAALDLFFIQMDGSRFKCTVAYQPYLLIRPEDNMHL-EVARFLGRKYSGQISGLEHITKEDLDLPNHLSGLQQQYIKLSFLNQTAMTKVRRELMSAVKRNQERQKSNTYYMQMLATSLAQSSAGSEDATLGKRQQDYMDCIVDIREHDVPYHVRVSIDLRIFCGQWYNIRCRSGVELPTITCRPDILDRPEPVVLAFDIETTKLPLKFPDAQTDQVMMISYMIDGQGYLITNREIISSNVDDFEYTPKPEFEGNFIVFNEENEMQLLQRFFDHIMEVRPHIIVTYNGDFFDWPFVETRAAVYDLDMKQEIGFSKLRDGNYLSRPAIHMDCLCWVKRDSYLPVGSQGLKAVAKAKLRYDPVELDPEDMCRMAVEQPQVLANYSVSDAVATYYLYMKYVHPFIFALNTIIPMEPDEILRKGSGTLCETLLMVEAYHAQIVYPNKHQSELNKLSNEGHVLDSETYVGGHVEALESGVFRADIPCRFRLDPAMVKQLQEQVDAVLRHAIEVEEGIPLEKVLNLDEVRQEIVQGLQGLHDIPNRLEQPVIYHLDVGAMYPNIILTNRLQPSAMVSDLDCAACDFNKPGVRCKRSMDWLWRGEMLPASRNEFQRIQQQLETEKFPP--LFPGGPQRAFHELSKEDQAAYEKKRLTDYCRKAYKKTKLTKLETRTSTICQKENSFYVDTVRAFRDRRYEYKGLTKVAKASVNAAVASGDAAEIKAAKGREVLYDSLQLAHKCILNSFYGYVMRRGARWHSMPMAGIVCLTGSNIITKAREIIERVGRPLELDTDGIWCILPGSFPQEFTIHTSHEKKKKINISYPNAVLNTMVKDHFTNDQYHELRKDKENNLPKYDIRDENSIFFEVDGPYLAMVLPAAKEEGKKLKKRYAVFNFDGTLAELKGFEVKRRGELQLIKNFQSSVFEAFLAGSTLEECYASVAKVADYWLDVLYSRGSNLPDSELFELISENKSMSKKLEEYGAQKSTSISTAKRLAEFLGEQMVKDAGLACKYIISKKPEGAPVTERAIPLAIFQSEPSVRRHHLRRWLKDNTMGDADIRDVLDWNYYIERLGGTIQKIITIPAALQGLANPVPRVQHPDWLHKKMLEKNDVLKQRRINEMFTSRPKPKPLATEEDK------LADMEDLAGKDGGEGAAGCPIVTKRKRIQLEEHDDEEAQPQATTWRQALGAPPPIGETRKTIVEWVRFQKKKWKWQQDQRQRNRQASKRTRGEDPPVVRAT--GSTATLGGFLRRAQRTLLDQPWQIVQLVPVDDLGHFTVWALIGEELHKIKLTVPRIFYVNQRSAAPPEEGQL---WRKVNRVLPRSRPVFN-----LYRYSVPEQLFRDNSLGMLADLATPDIEGIYETQMTLEFRALMDMGCICGVQREEARRLAQLATKDLETFSIEQLEQRPQTQVKYLASANNRLRKIYLYQHNTPTAKKEIWSLILMPSKKAFVFALDTVRANQMP---NMRQLYTAERLALLKNLTAEEQDKIPVEDYTFEVLIEVDVKQIYRHIQRALTTYKQEHQGPTILCLQTALSARKLSLAMPILLEFPQAEIHISDDASLLSGLDWQRQGSRAVIRHFLNLNNVLDLMLDQCRYFHVPIGNMPPDTVLFGADLFFARLLQRHNFVLWWSAST-RPDLGGREAD-DSRLLAEFEESISVVQNKAGFYPDVCVELALDSLAVSALLQSTRIQEMEGASSA-ITFDVMPQVSLEEMIG-TVPAATLPSYDETALCSAAFRVMRSMVNGWLREVSINRNIFSDFQIVHFYRWVRSSNALLYDPALRRSLNNLMRKMFLRIIAEFKRLGATIIYADFNRIILSSGKKTVSDALGYVDYIVQSLRNKEMFHSIQLSFEQCWNFMLWMDQANFSGIRGKLPKGIDETVSSIVSTTMIRDSERNQDDDEDEEEDSENRDPVESNEAEQDQEDELSLELNWTIGEHLPDENECREKFESLLTLFMQSLAEKKTTEQ---------------------------------------AIKDISHCAFDFILKLHKNYG--KGKP-------------------SPGLELIRTLIKALSVDKTLAEQINELRRNMLRLVGIGEFSDLAEWEDPCDSHIINEVICKACNHCRDLDLCKDKHRAMKDG-VPVWLCAQCYVAYDNEEIEMRMLDALQRKMMSYVLQDLRCSRCSEIKRENLAEFCTCAGNFVPLISGKDIQTLLGTFNKVAANHKMQLLQQTVHQALTTPR----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21951-1", "uniprot_id": "DPOE_YEAST", "id": "P21951-1", "name": "DNA polymerase epsilon catalytic subunit A", "aln": "MMFGKKKNNGGSSTARYSAGNKYNTLSNNYALSAQQLLNASKIDDIDSMMGFERYVPPQYNGRFDAKDIDQIPGRVGWLTNMHATLVSQETLSSGSNGGGNSNDGERVTTNQGISGVDFYFLDEEGGSFKSTVVYDPYFFIACNDESRVNDVEELVKKYLESCLKSLQIIRKEDLTMDNHLLGLQKTLIKLSFVNSNQLFEARKLLRPILQDNANNNVQRNIYNVAAN---------------GSEKVDAKHLIEDIREYDVPYHVRVSIDKDIRVGKWYKVTQQG------FIEDTRKIAFADPVVMAFDIETTKPPLKFPDSAVDQIMMISYMIDGEGFLITNREIISEDIEDFEYTPKPEYPGFFTIFNENDEVALLQRFFEHIRDVRPTVISTFNGDFFDWPFIHNRSKIHGLDMFDEIGFAPDAEGEYKSSYCSHMDCFRWVKRDSYLPQGSQGLKAVTQSKLGYNPIELDPELMTPYAFEKPQHLSEYSVSDAVATYYLYMKYVHPFIFSLCTIIPLNPDETLRKGTGTLCEMLLMVQAYQHNILLPNKHTDPIERFYD-GHLLESETYVGGHVESLEAGVFRSDLKNEFKIDPSAIDELLQELPEALKFSVEVENKSSVDKVTNFEEIKNQITQKLLELKENNIRNELPLIYHVDVASMYPNIMTTNRLQPDSIKAERDCASCDFNRPGKTCARKLKWAWRGEFFPSKMDEYNMIKRALQNETFPNKNKFSKKKVLTFDELSYADQVIHIKKRLTEYSRKVYHRVKVSEIVEREAIVCQRENPFYVDTVKSFRDRRYEFKGLAKTWKGNLS-KIDPSDKHARDEAKKMIVLYDSLQLAHKVILNSFYGYVMRKGSRWYSMEMAGITCLTGATIIQMARALVERVGRPLELDTDGIWCILPKSFPETYFFTLENGK--KLYLSYPCSMLNYRVHQKFTNHQYQELKDPLN---YIYETHSENTIFFEVDGPYKAMILPSSKEEGKGIKKRYAVFNEDGSLAELKGFELKRRGELQLIKNFQSDIFKVFLEGDTLEGCYSAVASVCNRWLDVLDSHGLMLEDEDLVSLICENRSMSKTLKEYEGQKSTSITTARRLGDFLGEDMVKDKGLQCKYIISSKPFNAPVTERAIPVAIFSADIPIKRSFLRRWTLDPSLEDLDIRTIIDWGYYRERLGSAIQKIITIPAALQGVSNPVPRVEHPDWLKRKIATKEDKFKQTSLTKFFS-KTKNVPTMG---------KIKDIEDLFEPTVEEDNAKIKIARTTKKKAVSKRKRNQ----LTNEEDPLVLPSEIPSMDEDYVGWLNYQKIKWKIQARDRKRRDQLFGNTNSS----------RERSALGSMIRKQAESYANSTWEVLQYKDSGEPGVLEVFVTINGKVQNITFHIPKTIYMKFKSQTMPLQKIKNCLIEKSSASLPNNPKTSNPAGGQLFKITLPESVFLEEKENCTSIFNDENVLGVFEGTITPHQRAIMDLGASVTFRSKAMG---ALGKGIQQGFEMKDLSMAE--NERYLSGFS--MDIGYLLHFP-TSIGYEFFSLFKSWGDTITILVLKPSNQAQEINASSLGQIYKQMFEKKKGKIETYSYLVDIKEDINFEFVYFTDISKLYRRLSQETTKLKEERGLQFLLLLQSPFITKLLG-TIRLLNQMPIVKLSLNEVLL--PQLNWQPTLLKKLVNHVLSSGSWISHLIKLSQYSNIPICNLRLDSMDYIIDVLYARKLKKENIVLWWNEKAPLPDHGGIQNDFDLNTSWIMNDSEFPKINNSGVYDNVVLDVGVDNLTVNTILTSALINDAEGSDLVNNNMGIDDKD---------AVINSPSEFVHDAFSNDALNVLRGMLKEWWDEALK-ENSTADLLVNSLASWVQNPNAKLFDGLLRYHVHNLTKKALLQLVNEFSALGSTIVYADRNQILIKTNKYSPENCYAYSQYMMKAVRTNPMFSYLDLNIKRYWDLLIWMDKFNFSGLA------------------CIEIEEKENQDYTAVSQWQLKKFLSPIYQPEFEDWMMIILDSMLKTKQSYLKLNSGTQRPTQIVNVKKQDKEDSVENSLNG-------------------------------------FSHLFSKPLMKRVKKLFKNQQEFILDPQYEADYVIPVLPGSHLNVKNPLLELVKSLCHVMLLSKSTILEIRTLRKELLKIFELREFAKVAEFKDPSLSLVVPDFLCEYCFFISDIDFCKAAPES-------IFSCVRCHKAFNQVLLQEHLIQKLRSDIESYLIQDLRCSRCHKVKRDYMSAHCPCAGAWEGTLPRESIVQKLNVFKQVAKYYGFDILLSCIADLTI-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .. ... .: : : : . *.:* **:* . :.*:* ***.. : :* .: :.:* :*:: :*. ** :: * **: * .. :* :: : .. : :: : **** : *** **:: *:*** . : :.*: : . :: * :.: * ... * . * *:**:*****:*:*** * .:**:: :. : : .:***:******** ******: .**:*********:*:*******:*.:::***:*****: * * :*** :* *:**:*:*: :.:* :: *:*********:. *: ::.*.* :**** :*:* : . ****: ********* **:.***.:::** *:*:***** * * *:** *: **********************:* ****::*** ****:***** ****:*:: :*: ***: . :::: : **:*::*********:**:****:*: .*:::*: .. * :.: .::.::* *: .:::. *::*: ::* * *:: * * *:***:**.:*****: ******.:: : **:****:** * *.: * ****::*:. .*:: *:: *:.*.** *. :*.*** :*. : *:**::*.**.*:: ::::: * : :**:**.******::*******:*** *. * .:. : .* . .* :********** ***********:*:**:** ****.*:**:.** ** ::*::*************:** ***: : : : * *: :*** ::** *:: ***.**:** . . * :.**:********* **:**::***** :******** **:********:********** ***.:*:.** *.*** *.:**.*.: ***** *:. : *.:*..**.**:***:.*::* ******:**:**.:***::**** ** *:**** ** .:********:***.:: .::: .**:* . :: * *** ::**.** ****.:************ : ******:*****::*: *:* ** :.::* . : *:**: . . :. . *: . :. .: . .: * *. : : : *:.::* **: * :* : .. : **.::*: .: : .*:::* : * : ::. :. .:: * : :*: :*:: : : . : .* . **.. . * *:. ::**.:: :. : : :: *::* :. **::.:*. .. : *. : * ::.*. : ** . : ** :. . ::.:: ::.*.. . * .: :*. :: . . .**. .::. : * :.: *:*: :: :*:. * : :* ::* . : : : *:** : ::.* *. . :. :. .:* ::*: *: * : *:::** *::.* :** . .: ** ** : * * ::: *.:* * * ::: ::.*:*.::* * ::: **:. .:.: : : ..: . *:.. ::.:::.*: * * .* :* : : *::.. : *.* *: ::*: :* :*::: **. **::::**: *:*:: : * .:. .* :*: .:::.: * : :.:.: *::::*** *:.*: . :: .: . .: : *: . : . . . ::. . : ::: : *: *: .* **::: : :.: :... ::. *.:::*::. : **:. *::.**. * :: :.:*. * . *:*:** : : * .* .::. :: ::: *: .: :: :*** * :* :*. :. .* *** : : : : : *.::* : :. * . : ", "identical_positions": 703, "similar_positions": 710, "identity": "29.74%" }, { "cls_id": "homologset.agr.SGD:S000005207", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BMV4-1", "uniprot_id": "B0BMV4_RAT", "id": "B0BMV4-1", "name": "Protein YIF1", "aln": "-----MAYHSGYGVHG-----------SKHRTRAAPNP---------------------PPLFDDTSGG---------YSSQLGGYPAP-------------------------------------GADVAF-NVNNLLGDPVAN-MAMAYGSSIASQGKDIVHKELHRFVSINKLKYFFAVDTAYVAKKLGLLVFPYTH--QNWKVQYSHDVPLPPRKDLNAPDLYIPTMAFITYVLLAGMALGIQQRFSPEVLGLCASTALVWVLMEVLALLLGLYLATVR--SELGTFHLLAYSGYKYVGMILSVLTG-LLFGSDGYYVALAWTSSALMYFTVRSLRT---AASGPDSMG--------------GPTPRQHLQLYLTLGAAAFQPLIIYWLTFHLVR------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XB7-1", "uniprot_id": "YIF1A_MOUSE", "id": "Q91XB7-1", "name": "Protein YIF1A", "aln": "-----MAYHSAYGVHG-----------SKHRTRAAPDP---------------------PPLFDDTSGG---------YSSQLGGYPAP-------------------------------------GADVAF-SVNNLLGDPVAN-MAMAYGTSIASQGKDIVHKELHRFVSVNKLKYFFAVDTAYVAKKLGLLVFPYTH--QNWKMQYSHDVPLPPRKDLNAPDLYIPTMAFITYVLLAGMALGIQQRFSPEVLGLCASTALVWVFMEVLALLLGLYLATVR--SELSTFHLLAYSGYKYVGMILSVLTG-LLFGSDGYYVALAWTSSALMYFIVRSLRT---AASGPDSMG--------------GPAPRQRLQLYLTLGAAAFQPLIIYWLTFHLVR------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95070-1", "uniprot_id": "YIF1A_HUMAN", "id": "O95070-1", "name": "Protein YIF1A", "aln": "-----MAYHSGYGAHG-----------SKHRARAAPDP---------------------PPLFDDTSGG---------YSSQPGGYPAT-------------------------------------GADVAF-SVNHLLGDPMAN-VAMAYGSSIASHGKDMVHKELHRFVSVSKLKYFFAVDTAYVAKKLGLLVFPYTH--QNWEVQYSRDAPLPPRQDLNAPDLYIPTMAFITYVLLAGMALGIQKRFSPEVLGLCASTALVWVVMEVLALLLGLYLATVR--SDLSTFHLLAYSGYKYVGMILSVLTG-LLFGSDGYYVALAWTSSALMYFIVRSLRT---AALGPDSMG--------------GPVPRQRLQLYLTLGAAAFQPLIIYWLTFHLVR------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PC24-1", "uniprot_id": "YIF1A_DANRE", "id": "Q6PC24-1", "name": "Protein YIF1A", "aln": "-----MNFQQ-QGYRA-----------TKPRARASPPTGG-------------------PMLFDDTSSGPPPMNNQNYYSSGYNMAEMP-------------------------------------AGGQEP-GVGNIFADPMAN-AAMMYGSTLANQGKDIVNKEINRFMSVNKLKYFFAVDTKYVMKKLLLLMFPYTH--QDWEVRYHRDTPLTPRHDVNAPDLYIPTMAFITYILLAGMALGIQKRFSPEVLGLCASTALVWMIIEVLVMLLSLYLLTVH--TDLSTFDLVAYSGYKYVGMILTVFCG-LLFGSDGYYVALAWSSCALMFFIVRSLKMKILSSISADSMGA-------------GASAKPRFRLYITVASAAFQPFIIYWLTAHLVR------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9CX30-1", "uniprot_id": "YIF1B_MOUSE", "id": "Q9CX30-1", "name": "Protein YIF1B", "aln": "MHATGLAAP-AGTPRLRKWP-------SKRRVPVSQPGMADP-----------------HQFFDDTSSAPSRG-----YGGQPSPGGLG-------------------------------------YPPSS--SDAAFLAAPMSN-MAMVYGSSLAAQGKELVDKNIDRFIPVSKLKYYFAVDTVYVGKKLGLLVFPYLH--QDWEVQYQQDTPVAPRFDINAPDLYIPAMAFITYILVAGLALGTQDRFSPDLLGLQASSALAWLTLEVVAILLSLYLVTVN--TDLTTIDLVAFLGYKYVGMIGGVLTG-LLFGKIGYYLVLAWCCVSIFVFMIRTLRLKILAQAAAEGVP--------------VRGARNQLRMYLTMAVAAAQPVLMYWLTFHLVR------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PEC3-1", "uniprot_id": "YIF1B_RAT", "id": "Q6PEC3-1", "name": "Protein YIF1B", "aln": "MHATGLAAP-AGTPRLRKWP-------SKRRVPVSQPGMADP-----------------HQFFDDTSSAPSRG-----YGGQPSPGSLG-------------------------------------YPTSS--SEAAFLAAPMSN-MAMAYGSSLAAQGKELVDKNIDRFIPVSKLKYYFAVDTVYVGKKLGLLVFPYLH--QDWEVQYQQDTPVAPRFDINAPDLYIPAMAFITYILVAGLALGTQDR------------------------------------------------------MIGGVLTG-LLFGKIGYYLVLAWCCVSIFVFMIRTLRLKILAQAAAEGVP--------------VRGARNQLRMYLTMAVAAAQPVLMYWLTFHLVR------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5BJH7-1", "uniprot_id": "YIF1B_HUMAN", "id": "Q5BJH7-1", "name": "Protein YIF1B", "aln": "MHPAGLAAAAAGTPRLRKWP-------SKRRIPVSQPGMADP-----------------HQLFDDTSSAQSRG-----YGAQRAPGGLS-------------------------------------YPAASPTPHAAFLADPVSN-MAMAYGSSLAAQGKELVDKNIDRFIPITKLKYYFAVDTMYVGRKLGLLFFPYLH--QDWEVQYQQDTPVAPRFDVNAPDLYIPAMAFITYVLVAGLALGTQDRFSPDLLGLQASSALAWLTLEVLAILLSLYLVTVN--TDLTTIDLVAFLGYKYVGMIGGVLMG-LLFGKIGYYLVLGWCCVAIFVFMIRTLRLKILADAAAEGVP--------------VRGARNQLRMYLTMAVAAAQPMLMYWLTFHLVR------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5U3G6-1", "uniprot_id": "YIF1B_DANRE", "id": "Q5U3G6-1", "name": "Protein YIF1B", "aln": "----MMEYPNQSGFRQRKLL-------PQVRMRGSAMEPSDP-----------------TQLFDDTSSGVN----------KHEPGRVG-------------------------------------KSPDVF-SGQNLLSDPMSN-LAMAYGSSLASHGKEMMDKNLDRFIPISKLKYYFAVDTVYVGKKLGLLVFPYMH--DNWEVNYQQDTPVAPRFDINAPDLYIPVMGFITYVLVAGLALGTQNRFSPEILGIQASSALVWLIIEVLAVLLSLYLVTVN--TDLTTIDLVAFSGYKYVGMIVGVVAG-LLFGRTGYYLALLWFCASIFVFTIRTLRLKILSEAAAEGRL--------------VRGTKNQLRMYLTMAIAAAQPVFMYWLTFHLVR------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IMR4-1", "uniprot_id": "Q8IMR4_DROME", "id": "Q8IMR4-1", "name": "", "aln": "-----MNYNPNPGMRNRKWENSSAAGRPRPPKRVSDVNAMGPSAPMMGGGATFMAPPTGPGILDPNMYGAPAPAPVNSYGFDPNLGQPSQHIQQPPQQQPGYGYGAPPPQQAAGPPTYGIGAPQPVAPPTGQYPQFAMFQQPIVQDMAMQYGQKLADQGKQIMENQFEKWVPVAKLKYYFAVDNAYVGRKLRLLFFPYMH--KDWSLRYDQEHPVQPRYDVNAPDLYLPTMGYITYVIVAGLLLGMQKRFSPEQLGIQASSAMAYSIFELVIYSLALYVMNVK--TSLKTLDLLAFTGYKYVNIVVCLMVS-TLFFKSGYYIALAYTSFSFGFFMLRTLRTKLLQDNSPAAPSGAINYDPYGNPQQFDYSGGKKRKLYFLFMIVAGQALFAFLLSKHLYLPEAEVLTVPKTF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53845-1", "uniprot_id": "YIF1_YEAST", "id": "P53845-1", "name": "Protein transport protein YIF1", "aln": "-----MSYNPYAYATSEQNG-------VNDRFSHTPQQQR-------------------PMQIPRNTPVNGQGN----ANMNANVNGSG-------------------------------------GGFPFQDPRGSMAFQLGQSAFSNFIGQDNFNQFQETVNKATANAAGSQQISTYFQVSTRYVINKLKLILVPFLNGTKNWQRIMDSGNFLPPRDDVNSPDMYMPIMGLVTYILIWNTQQGLKGSFNPEDLYYKLSSTLAFVCLDLLILKLGLYLLIDSKIPSFSLVELLCYVGYKFVPLILAQLLTNVTMPFNLNILIKFYLFIAFGVFLLRSVKFNLLSRSGAEDDDIHVS---------ISKSTVKKCNYFLFVYGFIWQNVLMWLMG-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : . : . : * : :: :.: . ::. :* *.. ** .** *:..*: : .:*. : ** *:*:**:*:* *. :**::: . * : :: . : : : :: * :*::: .. : . :: . * .: : : ", "identical_positions": 25, "similar_positions": 65, "identity": "6.07%" }, { "cls_id": "homologset.agr.SGD:S000005208", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6JFQ6-1", "uniprot_id": "CLVS1_RAT", "id": "A6JFQ6-1", "name": "Clavesin-1", "aln": "----MGPVSVLPKPQSISTWEGDLAKMTHLQAG--------LSPDTIEKARLELNENPD---VLHQDIQQVRDMIITRPDIG----------FLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLN--LDMFKNFKADDPGIKRALIDGFPGVLENRDHYGRKILLLFAAN-WDQSRNSFTDILRAILLSLEVLIEDPEL----------------QINGFILIIDWSNFS---FKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNN-LNSLHQLIHPEFLPSEFGGTLP-PYDMGTWARTLLGPDYSDENDYTHTSYNAMYVKHTCSNLERECSPKPMKRSQSVVEAGTLKHEE--KGENENTQPLLALD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D4C9-1", "uniprot_id": "CLVS1_MOUSE", "id": "Q9D4C9-1", "name": "Clavesin-1", "aln": "----MGPVSVLPSPQSLSTWEGDLAKMTHLQAG--------LSPDTIEKARLELNENPD---ILHQDIQQVRDMIITRPDIG----------FLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLN--LDMFKNFKADDPGIKRALIDGFPGVLENRDHYGRKILLLFAAN-WDQSRNSFTDILRAILLSLEVLIEDPEL----------------QINGFILIIDWSNFS---FKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNN-LNSLHQLIHPEFLPSEFGGTLP-PYDMGTWARTLLGPDYSDENDYTHTSYNAMHVKHTCSNLERECSPKPMKRSQSVVEAGTLKHEE--KGENENTQPLLALD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IUQ0-1", "uniprot_id": "CLVS1_HUMAN", "id": "Q8IUQ0-1", "name": "Clavesin-1", "aln": "----MGPVSLLPKYQKLNTWNGDLAKMTHLQAG--------LSPETIEKARLELNENPD---VLHQDIQQVRDMIITRPDIG----------FLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLN--LDMFKNFKADDPGIKRALIDGFPGVLENRDHYGRKILLLFAAN-WDQSRNSFTDILRAILLSLEVLIEDPEL----------------QINGFILIIDWSNFS---FKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNN-LNSLHQLIHPEFLPSEFGGTLP-PYDMGTWARTLLGPDYSDENDYTHTSYNAMHVKHTSSNLERECSPKLMKRSQSVVEAGTLKHEE--KGENENTQPLLALD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SYC1-1", "uniprot_id": "CLVS2_HUMAN", "id": "Q5SYC1-1", "name": "Clavesin-2", "aln": "--------------------------MTHLQAG--------LSPETLEKARLELNENPD---TLHQDIQEVRDMVITRPDIG----------FLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQN--LDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAAN-WDQSRYTLVDILRAILLSLEAMIEDPEL----------------QVNGFVLIIDWSNFT---FKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNN-LNSLHQLIHPEILPSEFGGMLP-PYDMGTWARTLLDHEYDDDSEYNVDSY-SMPVK----EVEKELSPKSMKRSQSVVDPTVLKRMD--KNEEENMQPLLSLD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6JUQ6-1", "uniprot_id": "CLVS2_RAT", "id": "A6JUQ6-1", "name": "Clavesin-2", "aln": "--------------------------MTHLQAG--------LSPETLEKARLELNENPD---TLHQDIQEVRDMVITRPDIG----------FLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQN--LDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAAN-WDQSRYTLVDILRAILLSLEAMIEDPEL----------------QVNGFVLIIDWSNFT---FKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNN-LNSLHQLIHPEILPSEFGGMLP-PYDMGTWARTLLDHEYDDDSEYNVDSY-SMPVN----EVDKELSPKSMKRSQSVVDPTALKRMD--KSEEENMQPLLSLD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG92-1", "uniprot_id": "CLVS2_MOUSE", "id": "Q8BG92-1", "name": "Clavesin-2", "aln": "--------------------------MTHLQAG--------LSPETLEKARLELNENPD---TLHQDIQEVRDMVITRPDIG----------FLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQN--LDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAAN-WDQSRYTLVDILRAILLSLEAMIEDPEL----------------QVNGFVLIIDWSNFT---FKQASKLTPNMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNN-LNSLHQLIHPEILPSEFGGMLP-PYDMGTWARTLLDHEYDDDSEYNVDSY-NMPVK----DVDKELSPKSMKRSQSVVDPTALKRMD--KSEEENMQPLLALD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SPP0-1", "uniprot_id": "CLVS2_DANRE", "id": "Q5SPP0-1", "name": "Clavesin-2", "aln": "--------------------------MTHLQAG--------LSPETLEKAKVELKENPD---TLHQDIQEVRDMIITRPDIG----------FLRTDDAFILRFLRARKFNHFEAFRLLAQYFEYRQQN--LDMFKNLKATDPGIKQALKDGFPGVLSNLDRYGRKILVLFAAN-WDQSRYTFVDILRAILLSLEAMIEDPEL----------------QVNGFVLIIDWSNFT---FKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKDKTRKRIFMHGNN-LNSLHQLILPEILPSELGGMLP-PYDMGTWARTLLDHAYDEETDYCPESY-TLSVK----DLEKDLSPKTMKRSQSVVEPGVLKRPEKVKSEEENMQPLLSLD--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Z275-1", "uniprot_id": "RLBP1_MOUSE", "id": "Q9Z275-1", "name": "Retinaldehyde-binding protein 1", "aln": "--MSDGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEKEE---TREEAVRELQELVQAQAASGEELALAVAERVQARDSAFLLRFIRARKFDVGRAYELLKGYVNFRLQY--PELFDSLSMEA--LRCTIEAGYPGVLSSRDKYGRVVMLFNIEN-WHCEEVTFDEILQAYCFILEKLLENEET----------------QINGFCIVENFKGFT---MQQAAGLRPSDLKKMVDMLQDSFPARFKAIHFIHQPWYFTTTYNVVKPFLKNKLLQRVFVHGDD-LDGFFQEIDENILPADFGGTLP-KYDGKVVAEQLFGPRAEVENTAL-----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z956-1", "uniprot_id": "D3Z956_RAT", "id": "D3Z956-1", "name": "Retinaldehyde-binding protein 1", "aln": "--MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREE---TRDEAVRELQELVQAQAASGEELAVAVAERVQARDSAFLLRFIRARKFDVGRAYELLKGYVNFRLQY--PELFDSLSMEA--LRCTIEAGYPGVLSSRDKYGRVVMLFNIEN-WHCEEVTFDEILQAYCFILEKLLENEET----------------QINGFCIVENFKGFT---MQQAAGLRPSDLKKMVDMLQDSFPARFKAIHFIHQPWYFTTTYNVVKPFLKNKLLQRVFVHGDD-LDGFFQEIDENILPADFGGTLP-KYDGKVVAEQLFGPRVEVENTAL-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12271-1", "uniprot_id": "RLBP1_HUMAN", "id": "P12271-1", "name": "Retinaldehyde-binding protein 1", "aln": "--MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREE---TREEAVRELQEMVQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNFRLQY--PELFDSLSPEA--VRCTIEAGYPGVLSSRDKYGRVVMLFNIEN-WQSQEITFDEILQAYCFILEKLLENEET----------------QINGFCIIENFKGFT---MQQAASLRTSDLRKMVDMLQDSFPARFKAIHFIHQPWYFTTTYNVVKPFLKSKLLERVFVHGDD-LSGFYQEIDENILPSDFGGTLP-KYDGKAVAEQLFGPQAQAENTAF-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRP8-1", "uniprot_id": "Q9VRP8_DROME", "id": "Q9VRP8-1", "name": "", "aln": "---------------MVQDQGETTG----------------LPEALLKIAKRELREDRC---TREQSLEQLRNWVAKNEDLQ----------NVRCDDTFLLRFLRAKKFSVPMAEQTLLKYLNIRRTF--PHMSTQLDYLEPRLGDLIDQGYIFAVPQRDKHGRRVVVINAKG-LNPKIHTSCDQAKAHFLTYECLMEDQET----------------QITGLTHVGDFAGVT---TAHVTNWNPTEFARIFKWGEQSLPMRHKEIHLINVPSTLKWLIDFVKNRVSSKMKNRLIIYGS--EKELMKSVDQGCLPLEMGGKVP-MREMIELWKQELATKRDLILGLD--------------KSILRSDRGIQRRSSFNAGKASTGGPNFVSQIESIEGSFRKLEFD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTY1-1", "uniprot_id": "Q9VTY1_DROME", "id": "Q9VTY1-1", "name": "CRAL-TRIO domain-containing protein", "aln": "-----------MLETEVLQQPKLSGPAASSGGDYDYPYVCGLSPAMKLVAKEELHEDEN---IRRQALAQFREWIEKHPHIR----------KCRTDTVFLLRFLRTKKFSVPSACEMLERYLTIRQLF--PQWFKQLDINDPAINEIFENGYLVPLPQRDSTGRQVIFSVAAK-FDPYKFTSVQMARVHSLVCEALLDDEDS----------------QVAGYVYINDESGMN---MGFVSLWSLTDLRSIVKCIQNSTPMRHKETHFVNIPHYANRIIELGVSMLSDKLKKRIIVHKN--VDILKTKIDPAILPKEYGGTVP-IADMIAQFKQKLQQRRAAILALD--------------DMQIEVTKDAANFAGNDIGDIDAG----------VVGSFRKLEVD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W503-1", "uniprot_id": "Q9W503_DROME", "id": "Q9W503-1", "name": "CRAL-TRIO domain-containing protein", "aln": "---------------------------------------MDKDTGDKDSAPETSASPAT---GWSDKLTDLVAWFEANPNLP-----------EKIEPIVMLRFLKCTAFDVERTKALAELNYCMRNKS--PHLFMDRNMEDEMTAEGLRVSDLLILPGVTPQGNKLIFFRMAD-LDPRTRNSVEETKIFVMMSDARFTKPDVERETGSGADYVLDEADIAEGDVQIVDIGGYT---LRHLAYVSIFVLRVYMKFLQEAYPSRLQAMHVINCPTYLDKLISMMSPFLREEVRNMIRYHTEG-MDSLYKEVPRDMLPNEYGGKAGTVAELKAKGIQSIRDNAAYLSDER--------------YWKV-----AAQSKSRWSWF-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W408-1", "uniprot_id": "Q9W408_DROME", "id": "Q9W408-1", "name": "CRAL-TRIO domain-containing protein", "aln": "------------------------------------------------MVHLNEKAEDQ---LMTTRISDLQDWLQAQPQLP-----------QNISRLLLRRFLHTTRGDLSAAQRLLELNYGLRNKH--AHIFIDRDPLDASSQQLLQVADLVPLPGLTPENNKLLFYRLID-FDADKFNFTAAIKVFFMVADCRFATENEERLS--------------DGEIPVFDMAGYT---LRHLTKTALGALRVYMKFVQEAHPVRLKEIHVLNCPSYVDKVMAVVKPFIKGEVFKLIHFHLPN-ADTPYRHFPRSMLPEEYGGEAGKMSDLKLQWMQLLKEQRDYLMDTE--------------NWQINKIKKNGQRKSSDSGVTEGLRSLEID---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8I099-1", "uniprot_id": "Q8I099_DROME", "id": "Q8I099-1", "name": "CRAL-TRIO domain-containing protein", "aln": "------------------------------------MMMLHPTPDQRVSIREELREPEDP-ADIERDIKLIREWLETQPHLP-----------KDMDDMRLTTFLRGCKFSLEKVKKKLDMYYTMRNAV--PEFFSNRDINREELNIVLDYVHCPTLPGITPNGRRITFIRGID-CDFQPHHILDAMKVALMIGDVRLAEESVG----------------IAGDIFILDASVAS---AAHFAKFSPTVVKKFLIAVQEAYPVKVKEVHVINISPLVDTIFNFVKPFVKEKIRSRITFHND--VESLYKVVPRDLLPNEYGGKAGGVVELNQWWKQKLVDNTQWFKDQEDK------------KANESLRPGAPKTSDDLFGMEGTFRQLNID---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9V4-1", "uniprot_id": "Q9V9V4_DROME", "id": "Q9V9V4-1", "name": "CRAL-TRIO domain-containing protein", "aln": "----------------------------------------------MKEANLEDQYASFP-EIRRPEVLKFLDWIHAQPHIS-----------DRFSEGEALHFFHACRYSMEVAKQVLDTNLTARTHL--EEFFVNLDCERPEIRRAMRTVSIVPLPGATPEGYRVILAKLDD-LNTSNYNFADVMKLYCMVFDFWMYEDGIQ-----------------PGHVIVIDLKNTS---LGHVARIGLLQMKKFLYYLQEAAAIRLIGFHFINIVPFMDKILALMTPFMKKELTTVLHMHSD--LKEFYKFVPQEMLPKEYGGQLEEANVAKEIYYKKLLDNRKEMIEFETR-----------HQVNEKLRPGKAKNASDLFGIEGNFKKLDID---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VD09-1", "uniprot_id": "PINTA_DROME", "id": "Q9VD09-1", "name": "Retinol-binding protein pinta", "aln": "-----------------------------------------MWSRSSSSKRQVATTDGDP-ERVLAQVQDLSDWLVANPQIN-----------GCNTFENLHFFLRTSKFDVERAKKKLKTFYQMRAER--TEWFDNRDPQLPEIQDLLKLGVFLPIG-PDAEQRMVVVIRTAA-HDPKLHSQNNVFKTSKMILDLLLKLDPET---------------CARGMVAILDMQGVQ---LGHALQMNPKLIKRSVES-WTAYPCQPKLLEFTNAPRHVNFFLNTFRIFMTPKIRSRLFVRRE------GTSVSCDQLPKELGGQGLSYMELSVKWKQLVEENADFYVEQD-------------------------KYKSKLK---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VM12-1", "uniprot_id": "Q9VM12_DROME", "id": "Q9VM12-1", "name": "CRAL-TRIO domain-containing protein", "aln": "-----------------MAATDIAEEAFHLRLG-------YLKPETVEIARVELRETEE---VKAEAIIKLRELLKATPELN-----------YKDDDAFLTVFLRACHFYPEGALEKMKTTASFRKEY--ASLVRG-LLVEQVKEKFVKGSVINVLKNCDQKGRRVLIVNCGKLWDPSDITSDEMFRMLYMVHLAAQLEEET----------------QVRGVVCIMDFEGLS---MKQVKALSPSFSKRLLTFIQEAMPLRMKEVHFVKQPFIFNMVWSLFKPFVKQKLNNRMHFHGSD-MKSLQKFLDPSVLPANYKGTLPAIDYGGVEWFPALEQQAQYVEEWS-------------------------QLGPAQW---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VM11-1", "uniprot_id": "Q9VM11_DROME", "id": "Q9VM11-1", "name": "CRAL-TRIO domain-containing protein", "aln": "-----------MGKAECISYDEHKLPYIDLGSAQIRMEKEQAPEWALKKAQDELREVPG---VKEQAIKELRELIQNEKYLN-----------LPLDDEYMMMFLRPTHYYPESALKRLKNFYHMKLKY--GAACEN--IIPSKLRNVFEANILNLLPQRDQHGRRLLVLEAGKKWKPSQVPLVDLFRGIQLTVLGSMVEPYS----------------QICGSVVIIDMEGLP---LSHITQFTPSFAAMLLDYIQECICMRLKAVHIVNNSYIFNMLFAVFKPFIREKLRKRIFFHGKD-YKSLISHIEAKALPPKYGGSATWELPHGKVLGEFFECYSKDYELADS----------------------YGYTEGYKMKK-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJN4-1", "uniprot_id": "Q9VJN4_DROME", "id": "Q9VJN4-1", "name": "CRAL-TRIO domain-containing protein", "aln": "--------------------------------------------MLFLTARVDHTAEQI------FKIEQLRQLVEKCEDLR-----------VGTEDTLLTKFLHYTRWDTIKAYQAIHDYYEFKRRH--PTWVAR-HPIEHYRQLFYGTHCRYVMPQADRSGRVLVVFKTVDGFQDYPDYLQSLVEMDDLIFESLLLLPRVQ----------------QNGITVICDLQGTN---RNFLRQFSP-AFMKVVNEKNGVLPFSQRIVHIIQRGFLMHVTSTLFMPFMNKEFKEKIFTHDGRHLSKLREMVGYESLPAEYGGPATNVLDTNLIFN-HLSQNAEYLEKLQ-------------------------TYGKA-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53844-1", "uniprot_id": "PDR17_YEAST", "id": "P53844-1", "name": "Phosphatidylinositol transfer protein PDR17", "aln": "MGLFSRKRDHTPAVPKEKLIPCDKIFLDPPAKYGNAPLLEPISEDQNEKYRAVLRHFQDDDLKLPENLNDLDNGTHANDRPLS------DWEKFWLSRECFLRYLRANKWNTANAIKGLTKTLVWRREIGLTHGKEDKDPLTADKVAVENETGKQVILGFDNAKRPLYYMKNGR--QNTESSFRQVQELVYMMETATTVAPQG-----------------VEKITVLVDFKSYKEPGIITDKAPPISIARMCLNVMQDHYPERLAKCVLINIPWFAWAFLKMMYPFLDPATKAKAIFDEP-----FENHIEPSQLDALYNGLLDFKYKHEVYWPDMVKKVDDLRLKRFDR------------FLKFGGIVGLSEYDTKGQHDELKYPVDMVI---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ::: . : : : . . : : : . . : : . * * . ", "identical_positions": 2, "similar_positions": 20, "identity": "0.49%" }, { "cls_id": "homologset.agr.SGD:S000005209", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q568Z6-1", "uniprot_id": "IST1_RAT", "id": "Q568Z6-1", "name": "IST1 homolog", "aln": "-MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEILELYCDLLLARFGLIQSMK--------ELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKEYGKLCRTN-QIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPDSVVMAEAPVGVETDLIDVGFTDDVKKGGPGRGGGGGFTAPVGAP-----DGTMPMPMPMPMPMPSPSPNAPFAYPLPKGPSDFSG--LPVGTY------QAFP----NIHPPQIP---ATPPSYESVDDINA---DKNVSSAQIVGP------KPEAPAKPPSR-----PVDNYNT------------------------FVLPELPSVPDTLPTAS-AGASTSASED-IDFDDLSRRFEELKKKT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CX00-1", "uniprot_id": "IST1_MOUSE", "id": "Q9CX00-1", "name": "IST1 homolog", "aln": "-MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEILELYCDLLLARFGLIQSMK--------ELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKEYGKLCRTN-QIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPDSVVMAEAPVGVETDLIDVGFTDDVKKGGPGRGGGGGFTAPVGGP-----DGIVPMPMPMPMP----SPNAPFAYPLPKGPSDFSG--LPVGTY------QAFP----NIHPPQIP---ATPPSYESVDDING---DKTVSSAQIVGP------KPEAPAKPPSR-----PVDNYNT------------------------FVLPELPSVPDTLPTAS-AGASTSASED-IDFDDLSRRFEELKKKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53990-1", "uniprot_id": "IST1_HUMAN", "id": "P53990-1", "name": "IST1 homolog", "aln": "-MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEILELYCDLLLARFGLIQSMK--------ELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKEYGKLCRTN-QIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPDSVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGP-----DGTVPMPMPMPMP----SANTPFSYPLPKGPSDFNG--LPMGTY------QAFP----NIHPPQIP---ATPPSYESVDDINA---DKNISSAQIVGPGP----KPEASAKLPSR-----PADNYDN------------------------FVLPELPSVPDTLPTAS-AGASTSASED-IDFDDLSRRFEELKKKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRY6-1", "uniprot_id": "Q9VRY6_DROME", "id": "Q9VRY6-1", "name": "IST1 homolog", "aln": "-MFSSGPNYNKLKTNLRLALNRLKLLEKKKAELTQKSRKEIADYLATGKTERARIRVEHIIREDYLVEAMEMVEMYCDLLLARFGLITQMK--------ELDTGIAEPVASLVWVCPRLQSDIAELKIISDIFVTKYGPQFAEQSRTATGEHYVSEKLMHKLTLQAPPKLLVENYLIAIAKNYNIEYEPDPQVMQEDQP-QQPHLIDLSDRNNLSGGG-GAGGGGAAPPQMGFIG----YPAMPALPDMPMP----PSAKPFNYPPFGGGGGGGGGGAPAGAYALPHPVQAPPPFAYNIPPNQPPTHAVLPAKCAEEKDLNTNFIDREANNTDGSGSPDENILRPKPENDPPPRYTSINPVNLQNANKPKPQPRSKLPPGNPTLPSAPPALDFPSLPNVPNDLPDIPGAGAEKKNDEDEIDFDDLSRRFENLKKRK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53843-1", "uniprot_id": "IST1_YEAST", "id": "P53843-1", "name": "Vacuolar protein sorting-associated protein IST1", "aln": "MAPSMIPFTIKLKTCLKMCIQRLRYAQEKQQAIAKQSRRQVAQLLLTNKEQKAHYRVETLIHDDIHIELLEILELYCELLLARVQVINDISTEEQLVKEHMDDGINEAIRSLIYAILFVD-EVKELSQLKDLMAWKINVEFVNGVIAD--HIDVPEKIIKKCSPSVPKEELVDLYLKEIAKTYDVPYSKLENSLSSSSSNISSDFSDPS-------GDIEDNDEEKPILALDNDDNDNADAKHPITVK--------------------------------------------------------------KPRQNSENIKNELKIPKDIKKEVIEKK--------QSEKKTTKR---------------------------------------------------------KTKKEQENDELDELKKRFDALRRK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*:. *:: ::**: ::*: :::::*:::*: * :.* ::*: *** :*::* :* :*::*:**:*****. :* .:. .:* *: *.: :*::. :: :: **. : * : * . :: : : * :::::* : ..* : **: ** ***.*:: *. : . ...: * . *. .. :. * . . . * : .. :. . . * ... .:: ::*:*.:**: *::: ", "identical_positions": 56, "similar_positions": 112, "identity": "12.84%" }, { "cls_id": "homologset.agr.SGD:S000005211", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08561-1", "uniprot_id": "PI4KB_RAT", "id": "O08561-1", "name": "Phosphatidylinositol 4-kinase beta", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDMVVEP------------------------ATLKPTSEPTPS----------PSGNNGGS-------------------LLSVITEGVGELS-VIDPEV-AQKACQEVLEKVKLLHGGVAISSKGSPL---------------------------------------ELVNGDGVDNEIRCLDDP-------------------------PTEIREEEDEMEPGVVSGTAKGTRRRRQNNSAK------------------------------------------------------------------------------------------QSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRKLILSDELKP--AHR--KRELPTLSP-----------APDTGLSPSKRTHQR---SKSDATASIS------------------------------------LSSNLKRTASNPKVENEDEELSSSTESIDNSFSSPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPT------AGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECEN-FDTTNVPARIPENRIRSTRSVENLPECGITHEQ-----RAGSFSTVPN---------YDND---------DEAWSVDDIGELQVEL-------------------PEVHTN----------------SCDNISQFSVDS----------------------------------ITSQESKEPVFIAAGDIRRRLSEQLAHT-PTAFKRDPEDPS------------------AVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQL---------------SLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLNGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHG--SSTIRNLKERFHMSMTEEQLQLLVEQMVDG-SMRSITTKLYDGFQYLTNGIM--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BKC8-1", "uniprot_id": "PI4KB_MOUSE", "id": "Q8BKC8-1", "name": "Phosphatidylinositol 4-kinase beta", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDMVVEP------------------------ATLKPTSEPTPS----------PSGNNGGS-------------------LLSVITEGVGELS-VIDPEV-AQKACQEVLEKVKLLHGGVAISSKGTPL---------------------------------------ELVNGDGVDNEIRCLDDP-------------------------PAQIREEEDEMGAGVASGTAKGARRRRQNNSAK------------------------------------------------------------------------------------------QSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFYFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRKLILSDELKP--AHR--KRELPTLSP-----------APDTGLSPSKRTHQR---SKSDATASIS------------------------------------LSSNLKRTASNPKVENEDEELSSSTESIDNSFSSPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPT------AGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECEN-FDTTSVPARIPENRIRSTRSVENLPECGITHEQ-----RAGSFSTVPN---------YDND---------DEAWSVDDIGELQVEL-------------------PEVHTN----------------SCDNISQFSVDS----------------------------------ITSQESKEPVFIAAGDIRRRLSEQLAHT-PTAFKRDPEDPS------------------AVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQL---------------SLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLNGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHG--SSTIRNLKERFHMSMTEEQLQLLVEQMVDG-SMRSITTKLYDGFQYLTNGIM--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBF8-1", "uniprot_id": "PI4KB_HUMAN", "id": "Q9UBF8-1", "name": "Phosphatidylinositol 4-kinase beta", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDTVVEP------------------------APLKPTSEPTSG----------PPGNNGGS-------------------LLSVITEGVGELS-VIDPEV-AQKACQEVLEKVKLLHGGVAVSSRGTPL---------------------------------------ELVNGDGVDSEIRCLDDP-------------------------PAQIREEEDEMGAAVASGTAKGARRRRQNNSAK------------------------------------------------------------------------------------------QSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRKLILSDELKP--AHR--KRELPSLSP-----------APDTGLSPSKRTHQR---SKSDATASIS------------------------------------LSSNLKRTASNPKVENEDEELSSSTESIDNSFSSPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPT------AGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECEN-FDTTSVPARIPENRIRSTRSVENLPECGITHEQ-----RAGSFSTVPN---------YDND---------DEAWSVDDIGELQVEL-------------------PEVHTN----------------SCDNISQFSVDS----------------------------------ITSQESKEPVFIAAGDIRRRLSEQLAHT-PTAFKRDPEDPS------------------AVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQL---------------SLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHG--SSTIRNLKERFHMSMTEEQLQLLVEQMVDG-SMRSITTKLYDGFQYLTNGIM--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q49GP3-1", "uniprot_id": "PI4KB_DANRE", "id": "Q49GP3-1", "name": "Phosphatidylinositol 4-kinase beta", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDTELELSP-------THLEELQKSPSTSTTSSLSLPSSPSSG----------PHPLTSSSPSTSEG-------LPTSSPPLDVISEGLGELSLVIDTEV-AKKACQEVLQKVKFLKGDGEVSSASSEP---------------------------------------ILANG--TAHPEANDGGQ-------------------------PPKISEEE--------VEPIKSVRRRQKNNSSK------------------------------------------------------------------------------------------QSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFSFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYVVYRCRQSINFSLQCAWLLGAYSSDMHISTQRHSRGTKLRKLILSDELKP--SSQRIRREVPQPPPPYPPPLHHGPGMSEHSLSPSKRTHQR---SKSDATVSIS------------------------------------LSSNLKRTASNPKVETSQDE--------------PVRLTPQREFIKSLMGIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPT------AAFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECEN-FETSSVPVRIPETQIRSTRSVENLPDCGITPDQ-----RASSFSTVPN---------YDND---------DEAWSVDDIGELQVEL-------------------PEIHTN----------------SCDNISQFSVDS----------------------------------ITSQESKEPIFIAAGDIRRRLSEQLAHT-PTTFRKDPEDPS------------------AVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAYQVLKQLQIIWEQERVPLWIKPYKILVISSDSGMIEPVVNAVSIHQVKKQSQL---------------LLLDYFRQEHGNFNTEEFLTAQRNFVQSCAGYCLICYLLQVKDRHNGNILLDSEGHIIHIDFGFILSSSPRNLGFETSAFKLTSEFVDVMGGLDGDMFNYYKMLMLQGLIAARKHMEKVIQIVEIMQQGSQLPCFHG--SSTIRNLKERFHMNLTEEQLQVLVEQMVDG-SMRSITTKLYDGFQYLTNGIM--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A4D6K881-1", "uniprot_id": "A0A4D6K881_DROME", "id": "A0A4D6K881-1", "name": "Phosphatidylinositol 4-kinase beta", "aln": "MNSVISAFKGKKNSNPSCNSPMGSANGTAPVEAKPNNCYQYLRHIREIDTNNKLLSPVVVVAEERPVSKAGSPSTVATMATGVDVVDHCLPTTVRLSVTEALSDLNMNGKAVEPPVTPCTSVGDNANLEVAETWACPPPQATDDEDISEHSTAACTSTSSSSEHSNSTVVHSPTVGESTCDSVSVSVSHPSPSVSQNNTSSATGRMSSPHSQSSLSIACEPHSASTTTLSSLGSDLGNGNGSTVPAFLMAAPVTLPIGGQMPTIKCLPGASSAASTPKHSRYSKPRLSLSRVFNHSMPSVHGRPNLSLAPAGVPGSVNPPKRISTHQRNLSLDFRSMGILLPPVSQVTNNHINHTQHHRNRSLDSALQRIPEVEVSSPNAESENTFCSPSILGATMCSKIATTAATVTSALSPPGTPTPALMSTACTPTIGAVKGNVQHPVPKHEQSISLAAACRSSAVVESCPTLRMRPKSSESVAANGQEMIGVIVSSTGNGSSSSNNSCSSAGSTKKREDLTSLGSDDSGIICGSESDQISLNRICHSHESLDSGEMDADADAEEECVDLMDTTSIDEEYNIMQPDHLCLYPPQAASTELDCRTLRPSRKQKRQQQQVLERKNLPSQNQIESEDSVDAGVDARTRYRVMNMSQAAINVELGTASNEIDPDVNYRESHQDPIADAPSLSTPSVASTASATPSVTPTPIATPTPTESTKNDQVLFKNFFGATKNAIFRTAQSIIENHEKKNAAKQKEQPDHSGTVSLVGSPNGGSSVPQDLVKSPTDISKKKEFFSLLTSSSSIKAAAAAAANSAASTPPATPTEALAANSNSKLQPLSDPSADLKVKERTLNLRLPGDSEGSEGALTKCSSINSIHKLKLPVPGVVKYFISEKAPVSDVLQKPEKGQSGLLRFFESPVFNIHFAVHYLFYSKEPGVLSFIGNKIFSFPDQEVDLYIPQLVVMYIQMDELA-EVLDPYLTIRCRKSVDFSLKCLWLLEAYNYQVDSLGNSHNSSRKSKLALMKEIFSKR-EHKQTQNDLKSAGTG-----GLHVGEPRSVVALAKKTHHR---SQSDATVLLADFRSPHTLSISHRMYQQPPYTTQTLPTTPAKLCLGDLTSGHAFDNGCTCFETVRGQVNGLLGQRTLCSCGAPKTSPQKEFMKALMNVGKNLTSWPSKAEKTSALRMSLNLINKNLPARVWLPLY-----SDIPHHVVRITEEKTAVLNSKDKTPYIIYVEVVEIPD-IYTSPLIPKMMPS-LRHTKSEEHLDGSCLNSHQHLSCSRTSSCSSSQQGTSCRRKKGADVDGGCGDAGPHNSCSNVHSLGGLQFQE-------------------DDVWSQEEDEITAQYLNMRKVSERDTISQISLDS----------------------------------CDSRDQGPPVVFNIGDVRLRHCSNLSCENTKSFSNDPEDPS------------------AAALKEPWHEKEKLIRESSPYGHLSNWRLLSAIVKCGDDLRQELMATQLLQMFKIIWQEEQVDLWVRPYKIVCLSNDSGLIEPILNTVSLHQIKKNSNK---------------SLKEYFIDEYGSPSGESFRRAQKNFVQSCAAYCLISYLLQVKDRHNGNILFHSDGHIIHIDFGFILSISPKNLGFEQSPFKLTPEFVEVMGGTSSEHWREFNKLLLVGMMSARKHMDRIINFVEIMRSNAHLPCFKNGCSGTVQNLRKRFHMNLTEQEMERKVEQLVQD-SLKSLSTKLYDGYQYYTNGILXERFFMKI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39104-1", "uniprot_id": "PIK1_YEAST", "id": "P39104-1", "name": "Phosphatidylinositol 4-kinase PIK1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHKASSSKKSFDDTIELKKNEQLLKLINSSEFTLHNCVELLCKHSENIGIHYYLCQKLATFPHSELQFYIPQLVQVLVTMETESMALED-----------------------LLLRLRAENPHFALLTFWQLQALLTDLSTDPASYG-------FQVARRVLNNLQTNLFNTSSGSDKNVKIHENVAPALVLSSMIMSAIAFPQLSEVT--------------------------------------KPLVESQGRRQKAFVFKLAR-------------------------SAMKDFTKNMTLKNTLLNKKTSRSKRVSSNRS------------------------------------------------------------------------------------------------STPTSPIDLIDPIKTKEDASFRKSRHSEVKLDFDIVDDIGNQVFEERISSSIKLPKRKPKYLDNSYVHRTYDGKNINRDGSISNTAKALDGNKGDYISPKGRNDENNEIGNNEDETGGETEEDADALNSDHFTSSMPDLHNIQPRTSSASSASLEGTPKLNRTNSQP--------------------------------------LSRQAFKNSKKANSSLSQEIDLSQLSTTSKIKMLKANYFRCETQFAIALETISQRLARVPTEAR-LSALRAELFLLNRDLPAEVDIPTLLPPNKKGKLHKLVTITANEAQVLNSAEKVPYLLLIEYLRDEFDFDPTSETNERLLKKISGNQGGLIFDLNYMNRKENNENRNESTLTSNNTRSSVYDSNSFNNGASRNEGLSSTSRSDSASTAHVRTEVNKEEDLGDMSMVKVRNRTDDEAYRNALVIQSAANVPILPDDSQDRSPELNFGSNLDEVLIENGINSKNIHSQTDALADQMRVSAVMLAQLDKSPQQLSESTKQIRAQIISSMKEVQDKFGYHDLEALHGMAGERKLENDLMTGGIDTSYLGEDWATKKERIRKTSEYGHFENWDLCSVIAKTGDDLRQEAFAYQMIQAMANIWVKEKVDVWVKRMKILITSANTGLVETITNAMSVHSIKKALTKKMIEDAELDDKGGIASLNDHFLRAFGNPNGFKYRRAQDNFASSLAAYSVICYLLQVKDRHNGNIMIDNEGHVSHIDFGFMLSNSPGSVGFEAAPFKLTYEYIELLGGVEGEAFKKFVELTKSSFKALRKYADQIVSMCEIMQKDNMQPCFDAG-EQTSVQLRQRFQLDLSEKEVDDFVENFLIGKSLGSIYTRIYDQFQLITQGIYS-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * . . : : : * * :* :: : : . . : :. . : . * .. . : ::: .: :. : * : :: : : : : *:: : . :. . * .. ::. . * : . . : . : : . : . : : . .:::: . . : . : :* :* :.:.*: *:: . . * .* *:*:.***.* :* *::* :. :: **** :*.**:: :* :. : .: . . : .:. : :. .: . .: :: : . . . . . :: : : : . * .::...* .. : ::* : ..: . .* * : * * * * . **: * ***: ** * *.*.* ******* :* *::: : ** :*:* :*:: **: * ::*::*.: *::*:*.:** * ::* .*. . : ** **..* *.*.::.*************::. :**: ******:** ** .:*** :.**** *:::::** ..: :. : * .: : **: ::::.: ***:.. ***. . * :*::**::.::*:::: **::: . *: *: *::** :* *:** ", "identical_positions": 148, "similar_positions": 251, "identity": "8.29%" }, { "cls_id": "homologset.agr.SGD:S000005214", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TBB6-1", "uniprot_id": "S7A14_HUMAN", "id": "Q8TBB6-1", "name": "Solute carrier family 7 member 14", "aln": "------------MSGFFTSLDPRRVQW----GAAWYAMHSRILRTKPVESMLEGTGTTTAHGTK-LAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTG---SAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAVWVFIMIAGLFFINGKYWAEGQ--FLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVKFLSEEHTKKKEGILADCEKEACSPVSEGDEFSGPATNTCGAKNLPSLGD-------NEMLIGKSDKSTYNVNHPN--YGTVDMTTGIEADESENIYLIKLKKLIGPHYYTMRIRLGLPGKMD--RPTAATGHTVTICVLLLFILMFIFCSFIIFGSDYISEQSWWAILLVVLMVLLISTLVFVILQQPENPKKLPYMAPCLPFVPAFAMLVN--IYLMLKLSTITWIRFAVWCFVGLLIYFGYGIWNSTLEIS---------------------------------AREEALHQSTYQRYDVDDPFS---VEEGFSYATEGESQEDWGGPTED---KGFYYQQMSDAKANGRTSSKAKSKSKHKQNSEALIANDELDYSPE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZSU3-1", "uniprot_id": "D3ZSU3_RAT", "id": "D3ZSU3-1", "name": "", "aln": "------------MSGFLSSLDPRRVQW----GAAWYAMHSRILRTKPVESMLEGTGATSAHGTK-LAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTG---SAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMVDTVGTLNGLGKGEESYPDLLALVIAVIVTIIVALGVKNSVGFNNVLNVLNLAVWVFIMIAGLFFVNGKYWAEGQ--FLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSMILTLMVPYYAIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLSLLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVKFLSEEHTKKKEGILADCEKETCSPVSEGEEFSSPATNTCGAKNLPSLGD-------NEMLIGKSDKSAYNVNHPN--YGTVDMTTGIEADESENIYLIKLKKLIGPRYYTMRIRLGLPGKMD--RPTAATGHTVTICVLLLFILMFIFCSFVIFGSEYISGQSWWAILLVVLMLLLITVLVFVILQQPENPKKLPYMAPCLPFVPAFAMLVN--IYLMLKLSTITWIRFAVWCFVGMLIYFGYGIWNSTLEIS---------------------------------AREQALHQSTYQRYDVDDPFS---VEEGFSYATEGESQEDWGGPAED---KGFYYQQMSDAKANSRTSSKAKSKSKHKQNSEALIENDELDCSPE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VWD3-1", "uniprot_id": "Q9VWD3_DROME", "id": "Q9VWD3-1", "name": "Cationic amino acid transporter C-terminal domain-containing protein", "aln": "----------MKPSDLLLVLEKVKFRVPLPPGVSSTTLLPKLIRTKDVKQLQDGN--AQPQKPK-LTKCLNTLDLTSLGIGSCCGTGMYLVAGMVAQKIAGPGVIISFIIAAIASIFSGACYAEFGVRVPHTSG---SAYMYSYVAVGEFVAFIIGWNMILEYLIGTSACACALSSSFDSLTGNAIARTISESIGTIFGKP------PDFIAFGITLLMTCVLAMGASKSVIFNHSLNAVNLATWVFVMAAGLFYVDTKTWSEHQG-FLPYGWSGVFSGAATCFYAFIGFDIIATTGEEAHNPQKSIPKAIVGSLVVVLIAYVSVSLVLTLVVPYDHINTGAALVQMWSYVNAPKCRAVVAIGATAGLSVAMFGSMFPMPRVIYAMAQDGLIFRQLSQLWHRTNVPGLATIGSGLAAALVALTVRLEILVEMMSIGTLLAYTLVSTCVLVLRYQPHS--TSLVELLPAQLRTPVAHGTASDSRSHVTPA-EVLEVPGKLTIKRVTRGMSDSDDSFIDDSPEGFLGGRDDQFLVSDRSENKFYGSVHGAPTGPTGQATAFDAMGLNFVTRKIHDYAYLCPGFFPWINPGQATAESGMYVTKLVGIMFGLIFFLDLFAAIG---WSGG--LAAFIYFILFIGIFVILLIISRQPQNRYALAFLTPGLPFIPAIAITVN--IYLIFKLSILTLVRFTVWMSLGFIMYFYYGITHSSLEQASDDLELHVDYSKNVEEKAVWDQQSYNQTHEPVWASKEVKQPSTEQRYNYGKTTSSSSSAQGSSRSGQGSAPEKPAGRSTAGLNRPVPPPPIAGQAKGSGSGSGPPMERQYTGQFSMFVDEGQFPTWDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B5DFJ0-1", "uniprot_id": "B5DFJ0_RAT", "id": "B5DFJ0-1", "name": "", "aln": "---------------MARGLPS---------TARLARFCQKLNRLKPLE--------ESSTETS-LRRCLSTLDLTLLGVGGMVGSGLYVLTGTVAKDMAGPAVLLSFLVAAVASLLAALCYAEFGARVPRTG----SAYLFTYVSMGEIWAFLIGWNVLLEYLIGGAAVARAWSGYLDAIFNHSIRNFTESHMGVWQMPFLA--HYPDFLAAGILLVASAFVSCGARVSSWLNHTFSAISLIVILFIIVLGFILARPHNWSAEEGGFAPFGFSGILAGTATCFYAFVGFDVIAASSEEAKNPRWAVPMAIAISLGLAAGAYILVSTVLTLMVPWHSLDPDSALADAFYRRGYGWAGFIVAVGSICAMNTVLLSNLFSLPRIVYAMAADGLFFQVFARVHPRTQVPVVGILVFGVLMALLALLMDLEALVQFLSIGTLLAYTFVATSIIVLRFQKAS-----------------------------PPSSPCPASPGPTVKKY---------------------------------------------------DSFSDHIQLVDAVQASMSEPGQLRPALKPFLG-FLDGLSPGTAVTWALGILIASAISLACVLVFGNSALHLPRWGYVLLLVVSGAVFLSSLLVLGAHQQQKKQDTFQIPLVPLTPALSILLN--LCLMLKLSYLTWLRFIFWLLVGLVVYFGYGIWHSKENQR----------------------------------EPLELTTAHYVVFPSGS---------------------------------------LEETVQAVQPDSQTPVQGPGCTE---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLQ7-1", "uniprot_id": "CTR4_MOUSE", "id": "Q8BLQ7-1", "name": "Cationic amino acid transporter 4", "aln": "---------------MARGLPS---------TACLARFCQKLNRLKPLE--------ESSMETS-LRRCLSTLDLTLLGVGGMVGSGLYVLTGTVAKDMAGPAVLLSFLVAAVASLLAALCYAEFGARVPRTG----SAYLFTYVSMGEIWAFLIGWNVLLEYLIGGAAVARAWSGYLDAIFNHSIRNFTESHLGVWQVPFLA--HYPDFLAAGILLVASAFVSCGARVSSWLNHTFSAISLIVILFIIVLGFILARPHNWSAEEGGFAPFGFSGILAGTATCFYAFVGFDVIAASSEEAKNPRWAVPMAIAISLSLAAGAYILVSTVLTLMVPWHSLDPDSALADAFYRRGYSWAGFIVAVGSICAMNTVLLSNLFSLPRIVYAMAADGLFFQVFARVHPRTQVPVVGILVFGVLMALLALLLDLEALVQFLSIGTLLAYTFVATSIIVLRFQKAS-----------------------------PPSSPCLASPGPTAKKY---------------------------------------------------DSFSDHIQLVGAEQTSMSEPGQLRPALKPFLG-FLDGCSPGTAVAWALGILVASAISLACVLVFGNSDLHLPQWGYVLLLVISGAVFLSSLLVLGAHQQQKKQDTFQIPLVPLTPALSILLN--TCLMLKLSYLTWLRFIFWLLVGLVVYFGYGIWHSKENQR----------------------------------EPLELTTAHYVVFPSGS---------------------------------------LEETVQAVQPSSQSPVRESGCTE---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43246-1", "uniprot_id": "CTR4_HUMAN", "id": "O43246-1", "name": "Cationic amino acid transporter 4", "aln": "---------------MARGLPT---------IASLARLCQKLNRLKPLE--------DSTMETS-LRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAVLLSFGVAAVASLLAALCYAEFGARVPRTG----SAYLFTYVSMGELWAFLIGWNVLLEYIIGGAAVARAWSGYLDSMFSHSIRNFTETHVGSWQVPLLG--HYPDFLAAGIILLASAFVSCGARVSSWLNHTFSAISLLVILFIVILGFILAQPHNWSADEGGFAPFGFSGVMAGTASCFYAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKSS-----------------------------PPSSPGPASPGPLTKQQ---------------------------------------------------SSFSDHLQLVGTVHASVPEPGELKPALRPYLG-FLDGYSPGAVVTWALGVMLASAITIGCVLVFGNSTLHLPHWGYILLLLLTSVMFLLSLLVLGAHQQQYREDLFQIPMVPLIPALSIVLN--ICLMLKLSYLTWVRFSIWLLMGLAVYFGYGIRHSKENQR----------------------------------ELPGLNSTHYVVFPRGS---------------------------------------LEETVQAMQPPSQAPAQDPGHME---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38971-1", "uniprot_id": "ALP1_YEAST", "id": "P38971-1", "name": "Basic amino-acid permease", "aln": "MDETVNIQMSKEGQYEINSSSIIKEEEFVDEQYSGENVTKAITTERKVEDDAAKETESSPQERREVKRKLKQRHIGMIALGGTIGTGLIIGIGPPLAHAGPVGALISYLFMGTVIYSVTQSLGEMVTFIPVTSSFSVFAQRFLSPALGATNGYMYWLSWCFTFALELSVLGKVIQYWTEAVPLAAWIVIFWCLLTSMNMFPVK--YYGEFEFCIASIKVIALLGFIIFSFCVVCGAGQSDGPIGFRYWRNPGAWGPGIISSDKNEG-----RFLGWVSSLINAAFTYQGTELVGITAGEAANPRKALPRAIKKVVVRILVFYILSLFFIGLLVPYNDPK----------------------------------------------LDSDGIFVSSSPFMISIENS---GTKVLPDIFNAVVLITILSAGNSNVYIGSRVLYSLSKNSLAPR--------------------------------------------------------------------------------------------------------------FLSNVTRGGVPYFSVLSTSVFGFLAFLEVSAGSGKAFNWLLNITGVAGFFAWLLISFS--------------HIRFMQAIRKRGISRDDLPYKAQMMPFLAYYASFFIALIVLIQGFTAFAPTFQPIDFVAAYISIFLFLAIWLSFQVWFKCRLLW----------------------------------KLQDIDIDSDRRQ--------------------------------------------IEELVWIEPECKTRWQRVWDVLS--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : :: . : : *. .: :.:*. *:*: : * . . ..::*: . . . . .*: . :* * * : ::* .:: . : : : :. . . . ::: : : :: : .:. . . . : * : : * . . .. ::: * :::. :. ** **. ::* ** : *: .: *:**: . : **::. . : : . : * * . : :*: : *:: .: : .. : .* . : : : . :. . : : : : .: *: : :: : .:. : : . : : ::: : : . . . . . ", "identical_positions": 33, "similar_positions": 148, "identity": "3.91%" }, { "cls_id": "homologset.agr.SGD:S000005215", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z207-1", "uniprot_id": "DIAP3_MOUSE", "id": "Q9Z207-1", "name": "Protein diaphanous homolog 3", "aln": "-----------------------------MERHRARALG--------------------RDSKSSRRKGLQSAPP-AGPYEPGEKRPKLHLNIRTLTDDMLDKFASIRIP-GSKKERPPLPHLKTVSGISDSSSLSSETMENNPKALPESEVL------------------------------KLFEKMMEDMNLN----EDKKAPLREKDFGIKKEMVMQYINTASKT--------------------------------------GSLRSSR---QISPQEFLHELKMG-YTDER----LFTYLES-------------------------------------------------LRVSLTSHPVS--WVQSFG-HEGLGLLLDILEKLINGQIQEK----VVKKTQHKVIQCLRALMNTQYGLERIMSD-----------------KRS--LSLLAKAMDPRQPAMMADVVKLLSAVCIVGE-------------------ESILEEVLEALTSAGEE--RKIDRFFSIVEGLRHN------SVNLQVACMQLINALVTS---PDDLDFRLHLRNEFMRCGLKEILPNL----KGIKNDGLDIQLKVFDEHKEEDL-SEFFHRLEDIRAELDEASDVYSMLWDTVKETRAEGHFLSILQHLLLIRNDR-FIREQ------YFKLIDECVSQIVLHRD-------------------------------------------------------------GTDPDFTYRKRLDLDLSQFVD------VCIDQAKLDEWEEKASEHCKKFEKECTDHQETQAQLQ------------------------------------------------------------------------------------------------------KRE----AKINELQAELQAFKSQFG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALPPGTKIPLQPS-----------VEGEAGPSALP--------------------------------------------PAPPALSGGVPPPPPPP--------PPPPPPLPG----------------------------MPMPFGGP------------VPPPPP--------LGFLGGQSSIPLN---------------LPFGLKPKKEFKPEISMRRLNWLKIGPNEMSEN-CFWIKVNENKYENRDLLCKLENTFCCQEKE----------------------------------------------KRNTNDFDEKKV--IKKRMKELKFLDPKIAQNLSIFLS--SFRVPYEKIRTMILEVDE-TQLSESMIQNLIKHLPDEEQLKSLSQFRSD---YNSLCEPEQFAVVMSN--VKRLRPRLSAILFKLQFEEQVNNIKPDIMAVSTACEEIKKSKGFSKLLELVLLMGNYMNAGSRNAQTFGFDLSSLCKLKDTKS-ADQKTTLLHFLVDVCEEKHADILHFVDDLAHLDKASRVSVEMLEKNVKQMGRQLQQLEKNLETF-PPPED---LHDKFVIKMSSFVISANEQYEKLSTLLGSMTQLYQSIMGYYAVDMK-KVSVEEFFNDLNNFRTSFMLALKE-NIKKREAAEKEKRARIAKERAEKERLERQQEKKRLLEMKTEGDET------GVMDSLLEALQSGAAFRDRRKRTPKLKDIRQSLSPMSQRPVLKVCNHENQKMQLTEGSRPHHSINCNSTRTPVAKELNYNLDTHASTGRIKAVEK-EACNAESNKKKEMELLGSVAKSESVPEVEALLARLRAL---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LVW7-1", "uniprot_id": "DIAP3_RAT", "id": "F1LVW7-1", "name": "Protein diaphanous homolog 3", "aln": "-----------------------------MEKHRARALG--------------------RDSKASRRKGLPSAPP-AGPYELGEKRPKLHLNIRTLTDDMLDKFASIRIPKGSKKERPPLPQLKTVSGSSDYSSVSSETMENNPKSLSENEVL------------------------------KLFEKMMEDMNLN----EDKKAPLREKDFSIKKEMVMQYINTASKT--------------------------------------GSLRSSR---QISPQEFIHELKMG-YTGER----LFTYLES-------------------------------------------------LRVSLTSNPVS--WVQNFG-HEGLGLLLDILEKLINGQIQEK----VVKKTQHKVIQCLRALMNTQYGLERIMSD-----------------ERS--LSLLAKAMDPKQPSMMADVVKLLSAVCIVGE-------------------ESILEEVLEALTSAGEE--RKIDRFFSIVEGLRHN------SVQLQVACMQLINALVTS---PDDLDFRLHLRNEFMRCGLKEILPNL----KGIKNDGLDIQLKVFDEHKEEDL-SEFSHRFEDIRAEFDEASDVYSVVWDTVKETRAEGHFVSILQHLLLIRNDR-FIRQQ------YFKLIDECVSQIVLHRD-------------------------------------------------------------GIDPDFTYRKRLDLDLSQFVD------VCIDQAKLEEWEEKASEHCKKFEKECTDHQETQAQLQ------------------------------------------------------------------------------------------------------KKE----AKINELQAELQAFKSQFG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALPPGTKIPLQTS-----------AKGEPGPSAFP--------------------------------------------PAPPALGAGVPPPPPPP--------PPPPPPLPG----------------------------MAMPFGGP------------VPPPPP--------LGFLGGQNFIPLN---------------LPFGLKPKKEFKPEISMRRLNWLKIGPNEMSEN-CFWIKVNENKYENKDLLCKLENTFCCLEKE----------------------------------------------KRDTNDFDEKKV--IKKRMKELKFLDPKIAQNLSIFLS--SFRVPYEKIRTMILEVDE-AQLSESMIQNLMKHLPDEEQLKSLSQFRSD---YNSLCEPEQFAVVMSN--VKRLRPRLTAILFKLQFEEQVNNINPDIMAVSTACEEIKKSKSFSKLLELVLLMGNYMNAGSRNAQTFGFDLSSLCKLKDTKS-ADQKTTLLHFLVDVCEEKHPDILPFVDDLAHLDKASRVSVEMLEKSLKQMGRQLLQLEKNLETF-PPPED---LHDKFVIKMSSFIITAKEHYGKLSTLLDNMTQLYQSVMSYYAVDTK-KVSVEEFFNDLNNFRTSFMQALKE-NIRKREAAEKEKRARIAKERAEKERLERQQEKKRLLEMKTEGDET------GVMDSLLEALQSGAAFRDRRKRTPKLKDIRQSLSPMSQRPVLKVCNHENQKMQLSEGSRPHHSINCTSTRTPVAKELNCNLDTHTSTGRIKAVEK-EACNAESNRKKEMELLGSVSKSESVPEVEALLARLRAL---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NSV4-3", "uniprot_id": "DIAP3_HUMAN", "id": "Q9NSV4-3", "name": "Protein diaphanous homolog 3", "aln": "-----------------------------MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIP-GSKKERPPLPNLKTAFASSDCSAAPLEMMENFPKPLSENELL------------------------------ELFEKMMEDMNLN----EDKKAPLREKDFSIKKEMVMQYINTASKT--------------------------------------GSLKRSR---QISPQEFIHELKMG-SADER----LVTCLES-------------------------------------------------LRVSLTSNPVS--WVESFG-HEGLGLLLDILEKLISGKIQEK----VVKKNQHKVIQCLKALMNTQYGLERIMSE-----------------ERS--LSLLAKAVDPRHPNMMTDVVKLLSAVCIVGE-------------------ESILEEVLEALTSAGEE--KKIDRFFCIVEGLRHN------SVQLQVACMQLINALVTS---PDDLDFRLHIRNEFMRCGLKEILPNL----KCIKNDGLDIQLKVFDEHKEEDL-FELSHRLEDIRAELDEAYDVYNMVWSTVKETRAEGYFISILQHLLLIRNDY-FIRQQ------YFKLIDECVSQIVLHRD-------------------------------------------------------------GMDPDFTYRKRLDLDLTQFVD------ICIDQAKLEEFEEKASELYKKFEKEFTDHQETQAELQ------------------------------------------------------------------------------------------------------KKE----AKINELQAELQAFKSQFG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALPADCNIPLPPS-----------KEGGTGHSALP--------------------------------------------PPPPLPSGGG-VPPPPP--------PPPPPPLPG----------------------------MRMPFSGP------------VPPPPP--------LGFLGGQNSPPLPI--------------LPFGLKPKKEFKPEISMRRLNWLKIRPHEMTEN-CFWIKVNENKYENVDLLCKLENTFCCQQKE----------------------------------------------RREEEDIEEKKS--IKKKIKELKFLDSKIAQNLSIFLS--SFRVPYEEIRMMILEVDE-TRLAESMIQNLIKHLPDQEQLNSLSQFKSE---YSNLCEPEQFVVVMSN--VKRLRPRLSAILFKLQFEEQVNNIKPDIMAVSTACEEIKKSKSFSKLLELVLLMGNYMNAGSRNAQTFGFNLSSLCKLKDTKS-ADQKTTLLHFLVEICEEKYPDILNFVDDLEPLDKASKVSVETLEKNLRQMGRQLQQLEKELETF-PPPED---LHDKFVTKMSRFVISAKEQYETLSKLHENMEKLYQSIIGYYAIDVK-KVSVEDFLTDLNNFRTTFMQAIKE-NIKKREAEEKEKRVRIAKELAERERLERQQKKKRLLEMKTEGDET------GVMDNLLEALQSGAAFRDRRKRTPMPKDVRQSLSPMSQRPVLKVCNHENQKVQLTEGSRSHYNINCNSTRTPVAKELNYNLDTHTSTGRIKAAEKKEACNVESNRKKETELLGSFSKNESVPEVEALLARLRAL---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O70566-1", "uniprot_id": "DIAP2_MOUSE", "id": "O70566-1", "name": "Protein diaphanous homolog 2", "aln": "-----------------------------MEELGAAASGAGGGG-------------GGGEEHGGGRSNKRGAGNRAANEEETRNKPKL-----------RDRITSFRKS-ATKREKPVIQHSIDYQTAVVEIPPALIVHDDRSLILSEKEVL------------------------------DLFEKMMEDMNLN----EEKKAPLRKKDFSIKREMVVQYISATSKSIVG-------------------------------SKVLGGLKNSKHEFTLSSQEYVHELRSG-ISDEK----LLNCLES-------------------------------------------------LRVSLTSHPVS--WVNNFG-YEGLGVLLDVLEKLLDKKQQEN----IDKKNQYKVIQCLKAFMNNKFGLQRILGD-----------------ERS--LLLLARAIDPKQQNMMTEIVKILSAICIVGE-------------------ENILDKLLGGITAAAEL--NNRERFSPIVEGLENNE-----ALHLQVACMQFINALVTS---PYDLDFRIHLRNEFLRCGLKAMLPTL----KEIENEGLDIQLRVFEENKEDDL-SELSHRLNDIRAEMDDINEVYHLLYNMLKDTAAEPYLLSILQHFLLIRNDY-YIRPQ------YYKIIEECVSQIVLHCS-------------------------------------------------------------GMDPDFKYRQRIDFDFTHLLD------ACVNKAKVEENEQKAMEFSKKFDEEFTARQEAQAELQ------------------------------------------------------------------------------------------------------KRD----EKIKELETEIQQLRGQG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPSAIPGPPPPPP-----------LPG-AGPCPPP--------------------------------------------PPPPPPPPPLPGVVPPP--------PPPLPGMPG----------------------------IPPPPPPP-----------LSGVPPP--------PPPPGGVFPLLSGP------------IELPYGMKQKKLYKPDIPMKRINWSKIEPKELSEN-CVWLKLKEEKYENADLFAKLALTFPSQMKG----------------------------------------------QRNTEAAEENRSGPPKKKVKELRILDTKTAQNLSIFLG--SYRMPYEEIKNIILEVNE-EMLSEALIQNLVKYLPDQNALRELAQLKSE---YDDLCEPEQFGVVMST--VKMLRPRLTSILFKLTFEEHVNNIKPSIIAVTLACEELKKSESFKRLLELILLVGNYMNSGSRNAQSLGFKINFLCKIKDTKS-ADQKSTLLHFLAEICDEKYRDILKFPDELEHVESAGKVSAQILKSNLVAMEQSILHLEKNIKNF-PPAES---HHDKFVEKMMSFTQNAREQYDKLSTMHSNMLKLYESLGEYFIFDPN-TVNMEEFFGDLNTFRTLFLEALKE-NHKRKEMEEKSRRAKLAKEKAEQEKLERQKKKKQLIDINKEGDET------GVMDNLLEALQSGAAFRDRRKRIPRNPD-----------------NRRPPLERSR--SRHNGAMSSK----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZUN2-1", "uniprot_id": "A0A8I5ZUN2_RAT", "id": "A0A8I5ZUN2-1", "name": "Protein diaphanous homolog 2", "aln": "-----------------------------MEQPGAAASGAGGGG-------------GG-EEPGVGRSNKRGTGNRAANEEETKNKPKLNIQIKTLADDVRDRITSFRKS-AIKKEKPLIQHPTDSQAAMGEVPSAQILHDERSLILSEKEVL------------------------------DLFEKMMEDMNLN----EEKKAPLRDKDFTTKREMVVQYISATAKSIVG-------------------------------SKVMGGLKNNKHEFTLSSQEYVHELRSG-ISDEK----LLNCLES-------------------------------------------------LRVSLTSNPVS--WVNNFG-YEGLGVLLDVLEKLLDKKQQEN----IDKKNQYKIIQCLKAFMNNKFGLQRILGD-----------------ERS--LLLLARAIDPKQQNMMTEIVKILSAICIVGE-------------------ENILDKLLGGITAAAER--NNRERFSPIVEGLENNE-----ALHLQVACMQFINALVTS---PYDLDFRIHLRNEFLRCGLKAMLPSL----KEKENDELDIQLRVFEENKEDDL-TELSHRLNDIRAEMDDMNEVFHLLYNMLKDTAAEGYLLSILQHFLLIRNDY-YIRPQ------YYKIIEECVSQIVLHCS-------------------------------------------------------------GMDPDFKYRQRIDFDFTHLID------ACVNKAKVEESEQKAMEFSKKFDEEFTARQEAQAEIQ------------------------------------------------------------------------------------------------------KRD----EKIKELESEIQQLQAQG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PGSAFPGPPPPPP-----------LPG-AGPCPPP--------------------------------------------PPPPPP---LPGVGPPP--------PPPLPGT--------------------------------APPPPP-----------LFGAPLL--------PPPPGGITPSLPGP------------VELPYGMKQKKLYNPEVSMKRINWSKIEPRDLSEN-CVWLKLKEEKYENPDLFAKLALTFPSQMKG----------------------------------------------QRHGETSEENRIGPQKKKMKELRILDTKTAQNLSIFLG--SYRMPYEEIKNIILEVNE-ELLSEALIQNLVKYLPEQNVLRELAQLKNE---YDDLCEPEQFGVVMST--VNMLRPRLTSILFKLTFEEHVNNIKPSIIAVTLACEELKKSESFNRLLELILLVGNYMNSGSRNAQSLGFKINFLCKIKDTKS-ADQKTTLLHFLAEICDEQHRDILKFPEELEHVESASKVSAQILKSNLVAMEQSILHLESNIKNF-PKAES---LHDKFVEKMMSFTQNAREQYDKLSTMHSNMLKLYESLGEYFIFDPN-IVTIEEFFGDLNTFRTLFLEALKE-NHKRKEMEEKSRRAKLAKEKAEQEKLERQKKKKQLIDINKEGDET------GVMDNLLEALQSGAAFRDRRKRIPRNPD-----------------NRRPTLERSR--SRHNGAMPSK----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60879-1", "uniprot_id": "DIAP2_HUMAN", "id": "O60879-1", "name": "Protein diaphanous homolog 2", "aln": "-----------------------------MEQPGAAASGAGG----------------GSEEPGGGRSNKRSAGNRAANEEETKNKPKLNIQIKTLADDVRDRITSFRKS-TVKKEKPLIQHPIDSQVAMSEFPAAQPLYDERSLNLSEKEVL------------------------------DLFEKMMEDMNLN----EEKKAPLRNKDFTTKREMVVQYISATAKS--------------------------------------GGLKNSKHECTLSSQEYVHELRSG-ISDEK----LLNCLES-------------------------------------------------LRVSLTSNPVS--WVNNFG-HEGLGLLLDELEKLLDKKQQEN----IDKKNQYKLIQCLKAFMNNKFGLQRILGD-----------------ERS--LLLLARAIDPKQPNMMTEIVKILSAICIVGE-------------------ENILDKLLGAITTAAER--NNRERFSPIVEGLENQE-----ALQLQVACMQFINALVTS---PYELDFRIHLRNEFLRSGLKTMLPDL----KEKENDELDIQLKVFDENKEDDL-TELSHRLNDIRAEMDDMNEVYHLLYNMLKDTAAENYFLSILQHFLLIRNDY-YIRPQ------YYKIIEECVSQIVLHCS-------------------------------------------------------------GMDPDFKYRQRLDIDLTHLID------SCVNKAKVEESEQKAAEFSKKFDEEFTARQEAQAELQ------------------------------------------------------------------------------------------------------KRD----EKIKELEAEIQQLRTQAQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VLSSSSGIPGPPAAPP-----------LPG-VGPPPPP--------------------------------------------PAPPLPG---GAPLPPP--------PPPLPGMMG----------------------------IPPPPPPPL----------LFGGPPP--------PPPLGGVPPPPGIS------------LNLPYGMKQKKMYKPEVSMKRINWSKIEPTELSEN-CFWLRVKEDKFENPDLFAKLALNFATQIKV----------------------------------------------QKNAEALEEKKTGPTKKKVKELRILDPKTAQNLSIFLG--SYRMPYEDIRNVILEVNE-DMLSEALIQNLVKHLPEQKILNELAELKNE---YDDLCEPEQFGVVMSS--VKMLQPRLSSILFKLTFEEHINNIKPSIIAVTLACEELKKSESFNRLLELVLLVGNYMNSGSRNAQSLGFKINFLCKIRDTKS-ADQKTTLLHFIADICEEKYRDILKFPEELEHVESASKVSAQILKSNLASMEQQIVHLERDIKKF-PQAEN---QHDKFVEKMTSFTKTAREQYEKLSTMHNNMMKLYENLGEYFIFDSK-TVSIEEFFGDLNNFRTLFLEAVRE-NNKRREMEEKTRRAKLAKEKAEQEKLERQKKKKQLIDINKEGDET------GVMDNLLEALQSGAAFRDRRKRIPRNPD-----------------NRRVPLERSR--SRHNGAISSK----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PZW8-1", "uniprot_id": "A0A8M9PZW8_DANRE", "id": "A0A8M9PZW8-1", "name": "Protein diaphanous homolog 2", "aln": "-----------------------------MDQQAAGGE----------------------------DPNK--PSKKKSSEDESKN-KKLNIHIKTLADDMRDRITSFRKQ-GMKKEKPLIQHPTDPISTQTELPVPQPFFDERSMNLSEKEIV------------------------------DLFEKMMEDMNLN----EERKAPLRGKDLSTKREMVVQYISATAKSITG-------------------------------SKVAGGLRNSKHECTLSSQEYVHELRSG-ISEDK----LLNCLES-------------------------------------------------LRVSLTSNPVS--WVNNFG-HEGLGLLLDALERLLDKKQQEN----IDKKNQHKLIQCLKAFMNNKYGLQRILGD-----------------ERS--LLLLARAIDPKQTNMMTEIVKILSAVCIIGE-------------------ENILDKILAAMTIAAER--NNKERFAPIVEGLENHE-----AQQLQVACMQLINALVTS---PDDLDFRIHLRNEFLRCGLKKILPEL----KET--EELDIQLKVFNENKEEDS-IELSHRLDDIRAEMDDMGEVYHLLSNMVKDTGSEPYFLSILQHLLLIRNDY-YIRPQ------YYKVIEECVSQIVLHRS-------------------------------------------------------------GMDPDFAYRERLDVDFSHLID------QCVDKAKVDESEQRAAEFSKKFDEEFSARQEAQAELQ------------------------------------------------------------------------------------------------------KQE----EKIKAFESQINTLQAQLTSERDKLKEAEKSISERN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKIAAGPKAAGAGPPPPPP-----------PPGGIAPPPPP--------------------------------------------PPPPPPIG--GAPPPPP--------PPPFPASLG----------------------------PPPPPPPP-----------GCGPPPP--------PPPPGGGPPPPPGMPSAPP----PLVVQLPYGLAPKKTYKPDSIMKRVNWSKIVPQEMAEN-CFWLKVKEERFENTDMFSELSLSFSSKSRV----------------------------------------------KKDVEETDD-RMTQFKKKAKELRILDAKTAQNLSIFLG--SFRLPYEEIRDIVLQVDE-ERLSEALIQNLIKNLPEQKELSNLAELKNE---YEELCESEQFGIVMSS--VKMLRPRLNGILFKLTFEEQVNNIRPDIMNVTFACEEVKKSEGFHMLLEMVLLVGNYMNSGSRNAQTFGFNISFLCKLRDTKS-TDQNTTLLHFLAEKCEEKYPEMLKFPDELEHVESASKVAAQTLKASLDIMERHIQRLENDIQNF-PKTDD---KQDKFVEKMSGFSKHSREQYEKLSTMHKNMQKLYENLGSYFAFDPH-TVSIEDFFGDLANFRNLFMDAVRE-NHKKREMEEKIKRAKIAKEKAEREKIERQQKKKQLIDMNKEGDET------GVMDSLMEALQSGAAFRDRRKRTPRNGDQ----SPSCSAPRWPGANHDAASGKSRQPSHWFGKIPFAPQCKPYGPMIACRLRTFAKCQRPKSGDNTEEG--------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O08808-1", "uniprot_id": "DIAP1_MOUSE", "id": "O08808-1", "name": "Protein diaphanous homolog 1", "aln": "-----------------------------MEPSGGGLGP-----------------------GRGTRDKKKGRSPDELPATGGDGGKHKKF---------LERFTSMRIK--KEKEKPNSAHRNSS-ASYGDDPTAQSLQD-----ISDEQVL------------------------------VLFEQMLVDMNLN----EEKQQPLREKDIVIKREMVSQYLHTSKAG-------------------------------------MNQKESSR-----SAMMYIQELRSG-LRDMH----LLSCLES-------------------------------------------------LRVSLNNNPVS--WVQTFG-AEGLASLLDILKRLHDEKEETSGN--YDSRNQHEIIRCLKAFMNNKFGIKTMLET-----------------EEG--ILLLVRAMDPAVPNMMIDAAKLLSALCILPQP------------------EDMNERVLEAMTERAEM--DEVERFQPLLDGLKSGT-----SIALKVGCLQLINALITP---AEELDFRVHIRSELMRLGLHQVLQEL----REIENEDMKVQLCVFDEQGDEDF-FDLKGRLDDIRMEMDDFGEVFQIILNTVKDSKAEPHFLSILQHLLLVRNDY-EARPQ------YYKLIEECVSQIVLHKN-------------------------------------------------------------GTDPDFKCRH-LQIDIERLVD------QMIDKTKVEKSEAKATELEKKLDSELTARHELQVEMK------------------------------------------------------------------------------------------------------KMENDFEQKLQDLQGEKDALDSEKQQITAQKQDLEAEVSKLTGEVAKLSKELEDAKNEMASLS--AVVVAPSVSSSAAVPPAPPLPGDSGTVIPPPPPP-------------------------------------------------------------------------------------------------------------------PPLPGGVVPPSPPLPPGTCIPPPPP-----------LPGGACIPPPPQLPGSAAIPPPPPLPGVASIPP------------PPPLPGATAIPPPPPLPGATAIPPPPP-LPGGTGIPPPPPPLPG----------------------------SVGVPPPPP-LPGGP----GLPPPPPPFPGAPGIPPPPPGMGVPPPPPFGFGV----PAAPVLPFGLTPKKVYKPEVQLRRPNWSKFVAEDLSQD-CFWTKVKEDRFENNELFAKLTLAFSAQTKTSK-------------------------------------------AKKDQEGGEEKKS-VQKKKVKELKVLDSKTAQNLSIFLG--SFRMPYQEIKNVILEVNE-AVLTESMIQNLIKQMPEPEQLKMLSELKEE---YDDLAESEQFGVVMGT--VPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSENFSSLLELTLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKS-ADQKMTLLHFLAELCENDHPEVLKFPDELAHVEKASRVSAENLQKSLDQMKKQIADVERDVQNF-PAATD---EKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGDYFVFDPK-KLSVEEFFMDLHNFRNMFLQAVKE-NQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDET------GVMDSLLEALQSGAAFR--RKRGPRQVN--------------RKAGCAVTSLLASELTKDDAMAPGPVKVPKKSEGVPTILEEAKELVGRAS---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60610-1", "uniprot_id": "DIAP1_HUMAN", "id": "O60610-1", "name": "Protein diaphanous homolog 1", "aln": "-----------------------------MEPPGGSLGP-----------------------GRGTRDKKKGRSPDELPSAGGDGGKSKKFTLKRLMADELERFTSMRIK--KEKEKPNSAHRNSS-ASYGDDPTAQSLQD-----VSDEQVL------------------------------VLFEQMLLDMNLN----EEKQQPLREKDIIIKREMVSQYLYTSKAG-------------------------------------MSQKESSK-----SAMMYIQELRSG-LRDMP----LLSCLES-------------------------------------------------LRVSLNNNPVS--WVQTFG-AEGLASLLDILKRLHDEKEETAGS--YDSRNKHEIIRCLKAFMNNKFGIKTMLET-----------------EEG--ILLLVRAMDPAVPNMMIDAAKLLSALCILPQP------------------EDMNERVLEAMTERAEM--DEVERFQPLLDGLKSGT-----TIALKVGCLQLINALITP---AEELDFRVHIRSELMRLGLHQVLQDL----REIENEDMRVQLNVFDEQGEEDS-YDLKGRLDDIRMEMDDFNEVFQILLNTVKDSKAEPHFLSILQHLLLVRNDY-EARPQ------YYKLIEECISQIVLHKN-------------------------------------------------------------GADPDFKCRH-LQIEIEGLID------QMIDKTKVEKSEAKAAELEKKLDSELTARHELQVEMK------------------------------------------------------------------------------------------------------KMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTT--------------------------------------------------------------------------------------------------------------PPPPPPPPPPPPPLPGGVCISSPPS-----------LPGGTAISPPPPLSGDATIPPPPPLPEGVGIPS------------PSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPG----------------------------EAGMPPPPPPLPGGP----GIPPPPP-FPGGPGIPPPPPGMGMPPPPPFGFGV----PAAPVLPFGLTPKKLYKPEVQLRRPNWSKLVAEDLSQD-CFWTKVKEDRFENNELFAKLTLTFSAQTKTSK-------------------------------------------AKKDQEGGEEKKS-VQKKKVKELKVLDSKTAQNLSIFLG--SFRMPYQEIKNVILEVNE-AVLTESMIQNLIKQMPEPEQLKMLSELKDE---YDDLAESEQFGVVMGT--VPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKS-TDQKMTLLHFLAELCENDYPDVLKFPDELAHVEKASRVSAENLQKNLDQMKKQISDVERDVQNF-PAATD---EKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPK-KLSVEEFFMDLHNFRNMFLQAVKE-NQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDET------GVMDSLLEALQSGAAFR--RKRGPRQAN--------------RKAGCAVTSLLASELTKDDAMAAVPAKVSKNSETFPTILEEAKELVGRAS---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48608-1", "uniprot_id": "DIA_DROME", "id": "P48608-1", "name": "Protein diaphanous", "aln": "-----------------------------MSRHEKTKST-----------------------GGGLLDSLFGRPSKSKGGTISSG---------------------------------TLAHGGRPVSADNYVVPGVEDFEQYIQQLSVAELD------------------------------AKFLEIIEDMNIP----KDKREPLLAKSKEERQKMIMWHLKGKNSL--------------------------------------ERSANSR---FEKPIDYVEYLQNGEHSTHK----VYQCVES-------------------------------------------------LRVALTSNPIS--WIKEFG-VAGIGTIEKLLARSKNNASYEK--------IEFEAIRCLKAIMNNTWGLNVVLNP-----------------DQHSVVLLLAQSLDPRKPQTMCEALKLLASFCIVYE-------------------RNGYEKVLRAITTIAATSFKASERFRPIVDALFASDQQD-PKRDLACHSLIFINTLTNT---PTDLNFRLHLRCEIMRMGLYDRLDEFTKIVEASNNENLQQHFKIFNEIREDDF-EEFVQRFDNVTFNMDDATDCFDVLKNLVTDTTSEPYFLSILQHLLYIRDDF-YFRPA------YYQLIEECISQIVFHKG-------------------------------------------------------------YCDPNFENRN-FNIDTSLLLD------DIVEKAKAKESK-RSEEYEKKIEQLESAKQEAEAKAA------------------------------------------------------------------------------------------------------HLE----EKVKLMEANGVAAPSPNK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPKVNIPMPPP-----------PPGGGGAPPPP---------------------------------------------PPPMPGRAGGGPPPPP--------PPPMPGRAG----------------------------GPPPPPPPP----GM----GGPPPPP-----MPGMMRPGGGPPPPPMMMG-------PMVPVLPHGLKPKKKWDVKNPMKRANWKAIVPAKMSDK-AFWVKCQEDKLAQDDFLAELAVKFSSKPVK----------------------------------------------KEQKDAVDKPTT--LTKKNVDLRVLDSKTAQNLAIMLGGSLKHLSYEQIKICLLRCDT-DILSSNILQQLIQYLPPPEHLKRLQEIKAK---GEPLPPIEQFAATIGE--IKRLSPRLHNLNFKLTYADMVQDIKPDIVAGTAACEEIRNSKKFSKILELILLLGNYMNSGSKNEAAFGFEISYLTKLSNTKD-ADNKQTLLHYLADLVEKKFPDALNFYDDLSHVNKASRVNMDAIQKAMRQMNSAVKNLETDLQNN-KVPQC---DDDKFSEVMGKFAEECRQQVDVLGKMQLQMEKLYKDLSEYYAFDPS-KYTMEEFFADIKTFKDAFQAAHND-NVRVREELEKKRRLQEAREQSAREQQERQQRKKAVVDMDAPQTQE------GVMDSLLEALQTGSAFGQRNRQARRQRP----------------AGAERRAQLSRSRSRTRVTNGQLMTREMILNEVLGSA--------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8BPM0-1", "uniprot_id": "DAAM1_MOUSE", "id": "Q8BPM0-1", "name": "Disheveled-associated activator of morphogenesis 1", "aln": "--------------------------------------------------------------MAPRKRGGRGISFIFCCFRNN-------------------------------------DHPEITYRLRNDSNFALQTMEPALPMPPVEELD------------------------------VMFSELVDELDLT----DKHREAMFALPAEKKWQIYCSKKKDQEE---------------------------------------NKGATSWPEFYIDQLNSMAARKSLLALEKEEEEERSKTIES-------------------------------------------------LKTALRTKPMR--FVTRFIDLDGLSCILNFLKTMDYETSESR--------IHTSLIGCIKALMNNSQGRAHVLAH-----------------SES--INVIAQSLSTENIKTKVAVLEILGAVCLVPG---------------------GHKKVLQAMLHYQKY-ASERTRFQTLINDLDKSTGRYRDEVSLKTAIMSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKL----REHENSTLDRHLDFFEMLRNEDE-LEFAKRFELVHIDTKSATQMFELTRRRLTHSEAYPHFMSILHHCLQMPYKRSGNTVQ------YWLLLDRIIQQIVIQNDK------------------------------------------------------------GQDPDSTPLENFNIKNVVRM--------LVNENEVKQWKEQAEKMRKEHNELQQKLEKKERECD------------------------------------------------------------------------------------------------------AKTQEKEEMMQTLNKMKEKLEKETTE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HKQVKQQVADLTAQLHELN--------RRAVCAAVPGGPSP-------------------------------------------GAPGGPFPSSGLGSLLPP--------PPPPLLSGG----------------------------ALPPPPPPLPPGGP-------PPPPG-------PPP-LGGVLPPPGAP--------------VSLTLKKKNIPQPTNALKSFNWSKLPENKLDG--TVWTEIDDTKVFKILDLEDLERTFSAYQRQQE--------------------------------------FFVNN-SKQKEADAIDDTLSSKLKVKELSVIDGRRAQNCNILLS--RLKLSNDEIKRAILTMDEQEDLPKDMLEQLLKFVPEKSDIDLLEEHKHE---LDRMAKADRFLFEMSR--INHYQQRLQSLYFKKKFAERVAEVKPKVEAIRSGSEEVFRSRALKQLLEVVLAFGNYMNKGQRG-NAYGFKISSLNKIADTKSSIDKNITLLHYLITIVENKYPKVLNLSEELRDIPQAAKVNMTELDKEISTLRSGLKAVETELEYQKSQPPQ---PGDKFVSVVSQFITLASFSFSDVEDLLAEAKELFTKAVKHFGEEAG-KIQPDEFFGIFDQFLQAVAEAKQENENMRKRKEEEERRARLEAQLKEQRERERKVRKAKE-----SSEES------GEFDDLVSALRSGEVFDKDLSKLKRNRK-----------------RISNQVTDSS-RERPITKLNF-----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GM04-1", "uniprot_id": "A0A8I6GM04_RAT", "id": "A0A8I6GM04-1", "name": "Disheveled-associated activator of morphogenesis 1", "aln": "--------------------------------------------------------------MAPRKRGGRGISFIFCCFRNN-------------------------------------DHPEITYRLRNDSNFALQTMEPALPMPPVEELD------------------------------VMFSELVDELDLT----DKHREAMFALPAEKKWQIYCSKKKDQEE---------------------------------------NKGATSWPEFYIDQLNSMAARKSLLALEKEEEEERSKTIES-------------------------------------------------LKTALRTKPMR--FVTRFIDLDGLSCILNFLKTMDYETSESR--------IHTSLIGCIKALMNNSQGRAHVLAH-----------------SES--INVIAQSLSTENIKTKVAVLEILGAVCLVPG---------------------GHKKVLQAMLHYQKY-ASERTRFQTLINDLDKSTGRYRDEVSLKTAIMSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKL----REHENSTLDRHLDFFEMLRNEDE-LEFAKRFELVHIDTKSATQMFELTRRRLTHSEAYPHFMSILHHCLQMPYKRSGNTVQ------YWLLLDRIIQQIVIQNDK------------------------------------------------------------GQDPDSTPLENFNIKNVVRM--------LVNENEVKQWKEQAEKMRKEHNELQQKLEKKERECD------------------------------------------------------------------------------------------------------AKTQEKEEMMQTLNKMKEKLEKETTE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HKQVKQQVADLTAQLHELN--------RRAVCASVPGGPSP-------------------------------------------GAPGGPFPPSGLGSLLPP--------PPPPLLSGG----------------------------ALPPPPPPLPPGGP-------PPPPG-------PPP-LGGILPPPGAP--------------VSLTLKKKNIPQPTNALKSFNWSKLPENKLEG--TVWTEIDDTKVFKILDLEDLERTFSAYQRQQE--------------------------------------FFVNNNSKQKEADAIDDALSSKLKVKELSVIDGRRAQNCNILLS--RLKLSNDEIKRAILTMDEQEDLPKDMLEQLLKFVPEKSDIDLLEEHKHE---LDRMAKADRFLFEMSR--INHYQQRLQSLYFKKKFAERVAEVKPKVEAIRSSSEEVLRSSALKQLLEVVLAFGNYMNKGQRG-NAYGFKISSLNKIADTKSSIDKNITLLHYLITIVENKYPKVLNLSEELRDIPQAAKVNMTELDKEISTLRSGLKAVETELEYQKSQPPQ---PGDKFVSVVSQFITLASFSFSDVEDLLAEAKELFTKAVKHFGEEAG-KIQPDEFFGIFDQFLQAVTEAKQENENMRKRKEEEERRARLEAQLKEQRERERKMRKAKE-----SSEES------GEFDDLVSALRSGEVFDKDLSKLKRNRK-----------------RISNQVTDSS-RERPITKLNF-----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y4D1-1", "uniprot_id": "DAAM1_HUMAN", "id": "Q9Y4D1-1", "name": "Disheveled-associated activator of morphogenesis 1", "aln": "--------------------------------------------------------------MAPRKRGGRGISFIFCCFRNN-------------------------------------DHPEITYRLRNDSNFALQTMEPALPMPPVEELD------------------------------VMFSELVDELDLT----DKHREAMFALPAEKKWQIYCSKKKDQEE---------------------------------------NKGATSWPEFYIDQLNSMAARKSLLALEKEEEEERSKTIES-------------------------------------------------LKTALRTKPMR--FVTRFIDLDGLSCILNFLKTMDYETSESR--------IHTSLIGCIKALMNNSQGRAHVLAH-----------------SES--INVIAQSLSTENIKTKVAVLEILGAVCLVPG---------------------GHKKVLQAMLHYQKY-ASERTRFQTLINDLDKSTGRYRDEVSLKTAIMSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKL----REHENSTLDRHLDFFEMLRNEDE-LEFAKRFELVHIDTKSATQMFELTRKRLTHSEAYPHFMSILHHCLQMPYKRSGNTVQ------YWLLLDRIIQQIVIQNDK------------------------------------------------------------GQDPDSTPLENFNIKNVVRM--------LVNENEVKQWKEQAEKMRKEHNELQQKLEKKERECD------------------------------------------------------------------------------------------------------AKTQEKEEMMQTLNKMKEKLEKETTE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HKQVKQQVADLTAQLHELS--------RRAVCASIPGGPSP-------------------------------------------GAPGGPFPSSVPGSLLPP--------PPPPPLPGG----------------------------MLPPPPPPLPPGGP-------PPPPG-------PPP-LGAIMPPPGAP--------------MGLALKKKSIPQPTNALKSFNWSKLPENKLEG--TVWTEIDDTKVFKILDLEDLERTFSAYQRQQD--------------------------------------FFVNSNSKQKEADAIDDTLSSKLKVKELSVIDGRRAQNCNILLS--RLKLSNDEIKRAILTMDEQEDLPKDMLEQLLKFVPEKSDIDLLEEHKHE---LDRMAKADRFLFEMSR--INHYQQRLQSLYFKKKFAERVAEVKPKVEAIRSGSEEVFRSGALKQLLEVVLAFGNYMNKGQRG-NAYGFKISSLNKIADTKSSIDKNITLLHYLITIVENKYPSVLNLNEELRDIPQAAKVNMTELDKEISTLRSGLKAVETELEYQKSQPPQ---PGDKFVSVVSQFITVASFSFSDVEDLLAEAKDLFTKAVKHFGEEAG-KIQPDEFFGIFDQFLQAVSEAKQENENMRKKKEEEERRARMEAQLKEQRERERKMRKAKE-----NSEES------GEFDDLVSALRSGEVFDKDLSKLKRNRK-----------------RITNQMTDSS-RERPITKLNF-----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80U19-1", "uniprot_id": "DAAM2_MOUSE", "id": "Q80U19-1", "name": "Disheveled-associated activator of morphogenesis 2", "aln": "--------------------------------------------------------------MALRKRSPHGLG-FLCCFGGS-------------------------------------DLPEIDLR----DSHPLQYLEFSGPIPNPEELN------------------------------VRFAELVDELDLT----DKNREAVFALPPEKKWQIYCSKRKEQEDP--------------------------------------NKLATSWPEYYIDRINAMAAMQNLYETEDEETDKRNQVVED-------------------------------------------------LKTALRTQPMR--FVTRFIDLEGLTCLLNFLRGMDHTTCESR--------IHTSLIGCIKALMNNSQGRAHVLAQ-----------------PEA--ISIIAQSLRTENSKTKVAVLEILGAVCLVPG---------------------GHKKVLQAMLHYQAY-AAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDNLEFRLHLRYEFLMLGIQPVIDKL----RQHENAILDKHLDFFEMVRNEDD-LELARRFDMVHIDTKSASQMFELIHKKLKHTEAYPCLLSVLHHCLQMPYKRNGGYFQ------QWQLLDRILQQIVLQDER------------------------------------------------------------GVDPDLAPLENFNVKNIVNM--------LINENEVKQWRDQAEKFRKEHMELMSRLERKERECE------------------------------------------------------------------------------------------------------TKTLEKEEMMRTLNKMKDKLARESQE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LRQARGQVAELVARHNESS------------TGPVSSPPPP-------------------------------------------GGP-LTLSSSRTTNDLPP--------PPPPLPFDS----------------------------CPPPPAPPLPPGGP-------PIPPG-------APPCFSSGPPPSHDP--FS---------SNEAPLRKKRIPQPSHPLKSFNWVKLNEERVSG--TVWNEIDDSQVFRILDLEDFEKMFSAYQRHQACMQEGPQRERGNVRDGGAASRPLPAVEASAHRTEKASRSMVSATGAKKELGSTEDIYITSRKVKELSVIDGRRAQNCIILLS--KLKLSNDEIRQAILRMDEQEDLAKDMLEQLLKFIPEKSDIDLLEEHKHE---IERMARADRFLYEMSR--IDHYQQRLQALFFKKKFQERLAEAKPKVEAILLASRELTLSQRLKQMLEVVLAIGNFMNKGQRG-GAYGFRVASLNKIADTKSSIDRNISLLHYLIMILEKHFPDILNMPSELKHLSEAAKVNLAELEKEVSILRRGLRAVEVELEYQRHQARD---PNDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKALTHFGEQES-KMQPDEFFGIFDTFLQAFLEARQDLEAMRRRKEEDERRARMEFMLKEQREKERWQRQRKVLAGG-ALEES------GEFDDLVSALRSGEVFDKDLSKFKRNRK-----------------RPGSQVPEVT-RERAINRLNY-----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6B158-1", "uniprot_id": "A0A8I6B158_RAT", "id": "A0A8I6B158-1", "name": "", "aln": "--------------------------------------------------------------MALRKRSPHGLG-FLCCFGSS-------------------------------------DLPEIDLR----DSHPLQYLEFSSPIPNPEELN------------------------------VCFAELVDELDLT----DKNREAVFALPPEKKWQIYCSKKKEQEDP--------------------------------------NKLATSWPEFYIDRINAMATMQNLYDTEDEETDKRSQVVED-------------------------------------------------LKTALRTQPMR--FVTRFIELEGLSCLLNFLRGMDHATCESR--------IHTSLIGCIKALMNNSQGRAHVLAQ-----------------PEA--ISIIAQSLRTENSKTKVAVLEILGAVCLVPG---------------------GHKKVLQAMLHYQVY-AAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDNLEFRLHLRYEFLMLGIQPVIDKL----RQHENAILDKHLDFFEMVRNEDD-LELARRFDMVHIDTKSASQMFELIHKKLKHTEAYPCLLSVLHHCLQMPYKRNGGYFQ------QWQLLDRILQQIVLQDER------------------------------------------------------------GVDPDLAPLENFNVKNIVNM--------LINENEVKQWRDQAEKFRKEHMELLSRLERKERECE------------------------------------------------------------------------------------------------------TKTLEKEEMMRTLNKMKDKLARESQE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LRQARGQVAELTG--------------------PVSSPPPP-------------------------------------------GGP-LTLSSSTTTNDLPP--------PPPPLPLDN----------------------------CTPPPPPPLPPGGP-------PIPPG-------APPCFSSGSPPPHEP--LS---------SNEAPLRKKRIPQPSHPLKSFNWVKLNEERVSG--TVWNEIDDSQVFRILDLEDFEKMFSAYQRHQ------------------------------------------------KELGSTEDIYLASRKVKELSVIDGRRAQNCIILLS--KLKLSNEEIRRAILRMDEQEDLAKDMLEQLLKFIPEKSDVDLLEEHKHE---IERMARADRFLYEMSR--IDHYQQRLQALFFKKKFQERLAEAKPKVEAILLASQELTLSKRLKKMLEVVLAIGNFMNKGQRG-GAYGFRVASLNKIADTKSSIDRNISLLHYLIMILEKHFPDILNMPSELLHLSKAAKVNLAELEKEVGALRRGLRAVEVELEYQRQQARD---PNDKFVPVMSDFITVSSFSFSELEEQLNEARDKFAKALAHFGEQDS-KMQPDEFFGIFDTFLQAFLEARQDLEAMRRRKEEDERRARMESMLKEQREKERWQRQRKVLVGG-ALEES------GEFDDLVSALRSGEVFDKDLNKFKRNRK-----------------RPGNQVAEVT-RERAINRLNY-----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86T65-3", "uniprot_id": "DAAM2_HUMAN", "id": "Q86T65-3", "name": "Disheveled-associated activator of morphogenesis 2", "aln": "--------------------------------------------------------------MAPRKRSHHGLG-FLCCFGGS-------------------------------------DIPEINLR----DNHPLQFMEFSSPIPNAEELN------------------------------IRFAELVDELDLT----DKNREAMFALPPEKKWQIYCSKKKEQEDP--------------------------------------NKLATSWPDYYIDRINSMAAMQSLYAFDEEETEMRNQVVED-------------------------------------------------LKTALRTQPMR--FVTRFIELEGLTCLLNFLRSMDHATCESR--------IHTSLIGCIKALMNNSQGRAHVLAQ-----------------PEA--ISTIAQSLRTENSKTKVAVLEILGAVCLVPG---------------------GHKKVLQAMLHYQVY-AAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDNLEFRLHLRYEFLMLGIQPVIDKL----RQHENAILDKHLDFFEMVRNEDD-LELARRFDMVHIDTKSASQMFELIHKKLKYTEAYPCLLSVLHHCLQMPYKRNGGYFQ------QWQLLDRILQQIVLQDER------------------------------------------------------------GVDPDLAPLENFNVKNIVNM--------LINENEVKQWRDQAEKFRKEHMELVSRLERKERECE------------------------------------------------------------------------------------------------------TKTLEKEEMMRTLNKMKDKLARESQE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LRQARGQVAELVAQLSELS------------TGPVSSPPPP-------------------------------------------GGP-LTLSSSMTTNDLPP--------PPPPLPFAC----------------------------CPPPPPPPLPPGGP-------PTPPG-------APPCLGMGLPLPQDP--YP---------SSDVPLRKKRVPQPSHPLKSFNWVKLNEERVPG--TVWNEIDDMQVFRILDLEDFEKMFSAYQRHQ------------------------------------------------KELGSTEDIYLASRKVKELSVIDGRRAQNCIILLS--KLKLSNEEIRQAILKMDEQEDLAKDMLEQLLKFIPEKSDIDLLEEHKHE---IERMARADRFLYEMSR--IDHYQQRLQALFFKKKFQERLAEAKPKVEAILLASRELVRSKRLRQMLEVILAIGNFMNKGQRG-GAYGFRVASLNKIADTKSSIDRNISLLHYLIMILEKHFPDILNMPSELQHLPEAAKVNLAELEKEVGNLRRGLRAVEVELEYQRRQVRE---PSDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKALMHFGEHDS-KMQPDEFFGIFDTFLQAFSEARQDLEAMRRRKEEEERRARMEAMLKEQRERERWQRQRKVLAAGSSLEEG------GEFDDLVSALRSGEVFDKDLCKLKRSRK-----------------RSGSQALEVT-RERAINRLNY-----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HP70-1", "uniprot_id": "A0AC58HP70_DANRE", "id": "A0AC58HP70-1", "name": "", "aln": "--------------------------------------------------------------MPPRKRTQPTLG-ILCCFKSG-------------------------------------EPPEINLK----DSVPLQLLEFSAPMPPEEELH------------------------------ARFSELVDDLDLT----DKNREAMFALPAEKKWQIYCSKKKEQEDP--------------------------------------NKLATSWPDYYIDRINSMAAMQTLFAFDEAEIEMRNKVVED-------------------------------------------------LKTALRTQPMR--FVTRFIELDGLTCLLTFLRSMDYETSESR--------IHTSIIGCIKALMNNSQGRAHVLAH-----------------PQS--INTISQSLHQDNIKTKVAVLEILGAVCLVPD---------------------GHKKVLQAMAHYQKF-AAERTRFQSLLNGLDRSTGHYRDEVNLKTAIMSFINAMLNAGVGEESIEFRLHLRYEFLMLGIQPVIEKL----RAHDNATLDRHLDFFEMVRNEDE-LELAKRFDSMHVDTKSAGQMFELIKKKLSHTDAYPHLLSILQHCLKMPYKHDAGSIQ------QWQLLDRILQQIVLQDEN------------------------------------------------------------GENPDVSPLENFNVRNIIKIYGKRHMSRLVNENEVKQWRDQAEKFRKEHVELMTRLERKDRECE------------------------------------------------------------------------------------------------------TKTQEKEDMMKTLNKMKDKLQREGVE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LRSAKEQVLDMSSRISDISYVGVPLPFPHPLPGSPMPPPPP-------------------------------------------SPP-IMLGGSPLLFPPPP--------PPPPPPLLH----------------------------PPPPPPPPLLPPLPPSFAFSSPPPPP-------PPPSFGCPQPPPGAPPIFSGIPPGPASNSSTTSPQTKSIPQPSQPLKSFNWSKLGGNEITD--TIWYGIDDRRAFKVLDLKDIEKMFSAYQRQQ------------------------------------------------KETGSMDDLNLSARKVKELSVIDGRRAQNCVILLS--KLKMSNEELKRAVLEMDEREELAKDMLEQLLKFVPEKSDMDLLEEHKHE---LERMARADRFLFEMSR--IDHYQQRLQSLFFKKKFADRLAETKPKAEAILCASREVMRSKLLRQVLEVVLAFGNFMNKGQRG-NAYGFKVSSLNKIIDTKSSIDRNITMLHYLIMIFEKNYPDILSIQQDLCSVSEAAKVNLAELEKEVSSIRSGLKALEVELRYQQSRVCD---RGDKFVPVVSDFITVASFSFSELEELLNEAKDKFSMALKHFGEEEG-RMQPDEFFGIFDIFLQSFSEARHDLKNMQRCKEEEERKIRLEAMLKDQRERERRAKKG---TKGSVSEEV------GEFDDLVSALRSGEVFDKD-SKLKRNRK-----------------RSVNQLADAGGRERSVTKMNY-----------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6ZPF4-1", "uniprot_id": "FMNL3_MOUSE", "id": "Q6ZPF4-1", "name": "Formin-like protein 3", "aln": "-----------------------------MGNLESTDGGPG-------------------EPPSVPLLLPPGKTPMPEPCELEER------------------FALVLSSMNLPPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQ------------------------------SFLDPNVTRKKFRRRV-QESTKVLRELEISLRTNHIGWVREFLNDE-------------------------------------NKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRS-------------------------------------------------IEDLQPPNALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLV--SQKDDVHVCILCLRAIMNYQYGFNLVMSH-----------------PHA--VNEIALSLNNKNPRTKALVLELLAAVCLVRG---------------------GHEIILAAFDNFKEV-CKELHRFEKLMEYFRNED----SNIDFMVACMQFINIVVHS---VEDMNFRVHLQYEFTKLGLEEFLQKS----RHTESEKLQVQIQAY----------------------LDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENE------NMMRVAELEKQLLQREK-------------------------------------------------------------------------------------------ELESIKETYENTSNQVHTLRRLIKEKEEAFQRRC------------------------------------------------------------------------------------------------------HLEP----SARGLESMGG-EALARVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTELTEGIPPS------------DLDLLAPAPP-----------------------------------------------TEETLPLPPPPAPP-------LPPPPPPLPD----------------------------KCPPAPP-----------------------------LPGAAPSVVLTVG--------------LSAIRIKKPIKTKFRLPVFNWTALKPNQING--TVFSELDDEKILEDLDLDRFEELFKTKAQG------------------------------------------------PALDLICSKNKTAQKAASKVTLLEANRAKNLAITLR--KAGRSAEEICRAIHTFDL-QTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSK--VERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRG-AVYGFKLQSLDLLLDTKS-TDRKMTLLHFIALTVKEKYPELANFWQELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIH-------------DNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPK-TTPPSVFFPVFVRFIRSYKEAEQE-NEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQQQELIAELRR------RQAKEHRPVYEGKDGTIEDIITVLKSVP--------------FTARTAKRGSRFFCDAAHHDESNC-----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ART4-1", "uniprot_id": "A0A8I6ART4_RAT", "id": "A0A8I6ART4-1", "name": "", "aln": "-----------------------------MGNLESTDGGPG-------------------EPPSVPLLLPPGKTPMPEPCELEER------------------FALVLSSMNLPPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQ------------------------------SFLDPNVTRKKFRRRV-QESTKVLRELEISLRTNHIGWVREFLNDE-------------------------------------NKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRS-------------------------------------------------IEDLQPPNALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLV--SQKDDVHVCILCLRAIMNYQYGFNLVMSH-----------------PHA--VNEIALSLNNKNPRTKALVLELLAAVCLVRG---------------------GHEIILAAFDNFKEV-CKELHRFEKLMEYFRNED----SNIDFLVACMQFINIVVHS---VEDMNFRVHLQYEFTKLGLEEFLQKS----RHTESEKLQVQIQAY----------------------LDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENE------NMMRVAELEKQLLQREK-------------------------------------------------------------------------------------------ELESIKETYENTSNQVHTLRRLIKEKEEAFQRRC------------------------------------------------------------------------------------------------------HLEP----SARSLESMGGSEALARVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTELTEGSTPS------------DLDLLAPAPP-----------------------------------------------AEETLPLPPPPAPP-------LPPPPPPLPD----------------------------KCPPAPP-----------------------------LPGAAPSVVLTVG--------------LSAIRIKKPIKTKFRLPVFNWTALKPNQING--TVFSELDDEKILEDLDLDKFEELFKTKAQG------------------------------------------------PALDLICSKNKTAQKAASKVTLLEANRAKNLAITLR--KAGRTAEEICRAIHTFDL-QTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSK--VERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRG-AVYGFKLQSLDLLLDTKS-TDRKMTLLHFIALTVKEKYPELANFWQELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIH-------------DNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPK-TTPPSVFFPVFVRFIRSYKEAEQE-NEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQQQELIAELRR------RQAKEHRPVYEGKDGAIEDIITVLKSVP--------------FTARTAKRGSRFFCDAAHHDESNC-----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41832-1", "uniprot_id": "BNI1_YEAST", "id": "P41832-1", "name": "Protein BNI1", "aln": "MLKNSGSKHSNSKESHSNSSSGIFQNLKRLANSNATNSNTGSPTYASQQQHSPVGNEVSTSPASSSSFRKLNAPSRSTSTEARPLNKKSTLNTQNLSQYMNGKLSGDVPVSSQHARSHSMQSKYSYSKRNSSQASNKLTRQHTGQSHSASSLLSQGSLTNLSKFTTPDGKIYLEMPSDPYEVEVLFEDIMYKRNIFQSLSEDKQEALMGYSIEKKWLIVKQDLQNELKKMRANTTSSSTASRTSMASDHHPILTANSSLSSPKSVLMTSASSPTSTVYSNSLNHSTTLSSVGTSTSKGKKLVSGSLKKQPSLNNIYRGGAENNTSASTLPGDRTNRPPIHYVQRILADKLTSDEMKDLWVTLRTEQLD--WVDAFIDHQGHIAMANVLMNSIYKTAPRENLTKELLEKENSFFKCFRVLSMLSQGLYEFSTHRLMTDTVAEGLFSTKLATRKMATEIFVCMLEKKNKSRFEAVLTSLDKKFRIGQNLHMIQNFKKMPQYFSHLTLESHLKIIQAWLFAVEQTLDGRGKMGSLVGASDEFKNGG-GENAILEYCQWTMVFINHLCSCSDNINQRMLLRTKLENCGILRIMNKI----KLLDYDKVIDQIELYDNNKLDDFNVKLEANNKAFNVDLHDPLSLLKNLWDICKGTENEKLLVSLVQHLFLSSSKLIEENQNSSKLTKQLKLMDSLVTNVSVASTSDEETNMNMAIQRLYDAMQTDEVARRAILESRALTKKLEEIQAERDSLSEKLSKAEHGLVGQLEDELHERDRILAKNQRVMQQLEAELEELKKKHLLEKHQQEVELRKMLTILNSRPEESFNKNEGTRGMNSSLNSSEKANIQKVLQDGLSRAKKDYKDDSKKFGMTLQPNKRLKMLRMQMENIENEARQLEMTNFAEFEKDRLEPPIHIKKPKVKKMKNKDRKPLVKPQEADVNKLNDLRRALAEIQMESNDISKFNVEERVNELFNEKKSLALKRLKELETKYKGFGIDFNVDEIMDSPKKNTGDVETEEDANYASLDPKTYQKKLDEINRITDQLLDIQTQTEHEIQVEEDGESDLSSSSSDDESEEIYQDASPTQELRSEHSELSSGSGPGSFLDALSQKYGTGQNVTASAAFGENNNGSGIGPLHSKVEKTFMNRLRKSTVSSAPYLEELTQKVNKVEPYEQNEDEGLDKKSLPENSTASAASAFDKAEKDMRQHVENGKQGRVVNHEEDKTADFSAVSKLNNTDGAEDLSTQSSVLSSQPPPP--------PPPPPPVPAKLFGESLEKEKKSEDDTVKQETTGDSPAPPPPPPPPPPPPMALFGKPKGETPPPPPLPSVLSSSTDGVIPPAPPMMPASQIKSAVTSPLLPQSPSLFEKYPRPHKKLKQLHWEKLDCTDNSIWGTGKAEKFADDLYEKGVLADLEKAFAAREIKSLAS----------------------------------------KRKEDLQKITFLSRDISQQFGINLHMYSSLSVADLVKKILNCDRDFLQTPSVVEFLSKSEIIEVSVNLARNYAPYSTDWEGVRNLEDAKPPEKDPNDLQRADQIYLQLMVNLESYWGSRMRALTVVTSYEREYNELLAKLRKVDKAVSALQESDNLRNVFNVILAVGNFMN--DTSKQAQGFKLSTLQRLTFIKD-TTNSMTFLNYVEKIVRLNYPSFNDFLSELEPVLDVVKVSIEQLVNDCKDFSQSIVNVERSVEIGNLSDSSKFHPLDKVLIKTLPVLPEARKKGDLLEDEVKLTIMEFESLMHTYGEDSGDKFAKISFFKKFADFINEYKKAQAQNLAAEEEERLYIKHKKIVEEQQKRAQEKEKQKENSNSPSSEGNEEDEAEDRRAVMDKLLEQLKNAGPAKSDPSSARKRALVRKKYLSEKDNAPQLLNDLDTEEGSILYSPEAMDPTADTVIHAESPTPLATRGVMNTSEDLPSPSKTSALEDQEEISDRARMLLKELRGSDTPVKQNSILDEHLEKLRARKERSIGEASTGNRLSFK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : : .: .. : : .. : . : : : : : *::.: * . . : : * : :: . :: :: : : : .:: *: :: :: *: : . : :: : .. . . . . .: .* . : :: . : . : : .. . . :. . . ** *** : : :* : . : : * .: . . . : : . . :. : . . : * : . . : ::: : *: : . : .. . : * : :::: * .**:** . . ** : * : *. .. ::*::: .. . : .:* : .. * : : : :. . . : : : *: : * * : . :. : .. . .. . ", "identical_positions": 31, "similar_positions": 168, "identity": "1.54%" }, { "cls_id": "homologset.agr.SGD:S000005216", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62739-1", "uniprot_id": "RAB3I_RAT", "id": "Q62739-1", "name": "Rab-3A-interacting protein", "aln": "------------------------------------------------------------------------------------------------------------------MANDPLEGFHEVNLASPTSPDL---------------LGVCDPGTQEQTTSPSVIYRPHPSTLCSATIQANALNLSDLPTQPVYSSPRHLNCAEISNISIHVPEPASSV----------------------------------------------------------------------------ASEVAAGLTRFTSRKDSCNAEREFLQGATVTEASAGNDDIFGLSTDSLSRLRSPSVLEVREKGYERLKEELAKAQRELKLKDEECERLSKVRDQLG------------------QELEELTASLFEEAHKMVREANVKQATAEKQLKEAQGKIDVLQAEVAALKTLVLSSSPTSPTQEPLAAGKTP---FKRG----HTRNKSTSSAMSGSHQDFS-AIQPIVKDCREADLSLYNEFRSWKDEPTMDR-----------TCPFLDKIYQEDIFPCLTFAKSELASAVLEAVENNTLSIEPVGLQPIRFVKASAVECGGPK------KCALTGQSKPCKHRIKLGDSSSYYYISPVCRYRITSVCNFFTYIRYIQQGLVKQQDVDQMFWEVMQLRKEMSLAKLGYFKEEL---------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q68EF0-1", "uniprot_id": "RAB3I_MOUSE", "id": "Q68EF0-1", "name": "Rab-3A-interacting protein", "aln": "------------------------------------------------------------------------------------------------------------------MANDPLEGFHEVNLASPTSPDL---------------LGVCDPGTQEQTTSPSVIYRPHPSTLCAAPLQANALDLSDLPTQPVYSSPRHFNCAEVSNISAHAPDPASSV----------------------------------------------------------------------------PSAVASGLTKLTSRKDSCNAEREFLQGATITEASAGNDDIFGLSTDSLSRLRSPSVLEVREKGYERLKEELAKAQR--------------------------------------------------EAHKMVREANVKQATAEKQLKEAQGKIDVLQAEVAALKTLVLSSSPTSPTQEPLAAAKTP---FKRG----HTRNKSTSSAMGGSHQDLS-VIQPIVKDCKEADLSLYNEFRSWKDEPTMDR-----------TCPFLDKIYQEDIFPCLTFAKSELASAVLEAVENNTLSIEPVGLQPIRFVKASAVECGGPK------KCALTGQSKPCRHRIRLGDSSCCYYISPFCRYRITSVCNFFTYIRYIQQGLVKQQDVDQMFWEVMQLRKEMSLAKLGYFKEEL---------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96QF0-1", "uniprot_id": "RAB3I_HUMAN", "id": "Q96QF0-1", "name": "Rab-3A-interacting protein", "aln": "--------------------------------------------------------------------------------------------------MGLKKMKGLSYDEAFAMANDPLEGFHEVNLASPTSPDL---------------LGVYESGTQEQTTSPSVIYRPHPSALSSVPIQANALDVSELPTQPVYSSPRRLNCAEISSISFHVTDPAPCS----------------------------------------------------------------------------TSGVTAGLTKLTTRKDNYNAEREFLQGATITEACDGSDDIFGLSTDSLSRLRSPSVLEVREKGYERLKEELAKAQRELKLKDEECERLSKVRDQLG------------------QELEELTASLFEEAHKMVREANIKQATAEKQLKEAQGKIDVLQAEVAALKTLVLSSSPTSPTQEPLPGGKTP---FKKG----HTRNKSTSSAMSGSHQDLS-VIQPIVKDCKEADLSLYNEFRLWKDEPTMDR-----------TCPFLDKIYQEDIFPCLTFSKSELASAVLEAVENNTLSIEPVGLQPIRFVKASAVECGGPK------KCALTGQSKSCKHRIKLGDSSNYYYISPFCRYRITSVCNFFTYIRYIQQGLVKQQDVDQMFWEVMQLRKEMSLAKLGYFKEEL---------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58J6L5-1", "uniprot_id": "A0AC58J6L5_DANRE", "id": "A0AC58J6L5-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------MKIFWAMASEPLEGFHEVNLASPTTPDV---------------HGVIDPSPPKHNAPPSTLYRTHS--LSSSQNAASALRADQLPTQPVYSAPRHLGGDDTLNGSGNDP-------------------------------------------------------------------------------------------------------------AAVDAVDADGEDGLGLSTDGLSRLRSPSVMEVREKGYEKLKEELAKAQRELKLKDEECERLSKVRDQLG------------------QELEELTASLFEEAHKMVHEANLKQATAEKQLKEALGKIDVLQAEVAALKTLVLSTSPTSPCKEMPPGPKAP---FKKG----HVRNKSTSSAMLGSQQEVA-VTQPIVRECKEVDSLLFTEFKAWKEEPTLER-----------SCSFLERIYREDIYPCLTFSKSELGSAILEAVEQNTLSVEPVGFQPLPVVRASAVECGGPKMAETLVKCALCGQTKTCKHRIKFGDSSSYYYVSPFCRYRITSVCNFFTYIRYILQGLVKQQDAEQMFWEVLQLRKEMSNAKLGFYKDEL---------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8VDV3-1", "uniprot_id": "R3GEF_MOUSE", "id": "Q8VDV3-1", "name": "Guanine nucleotide exchange factor for Rab-3A", "aln": "------------------------------------------------------------------------------------------------------------------MWSGQPQ--QDEGLP----------------------VGLSAIPVPWKNLGPSKSNRESSGGLVEASTSWEEAQGEEHPAPAPLD---------------------------------------------------------------------------------------------------------------------------------------------------VSRLRS-SSMEIREKGSEFLKEELYKAQKELKLKDEECERLCKVRAQLE------------------QELEELTASLFEEAHKMVREANMKQATSEKQLKEAWGKIDMLQAEVTALKTLVITSTPASPNRELHPQLLSP---TKAGPRKGHSRQKSTSSSLCPVVCPTAGHIPTPDKEGKEVDTTLFAEFQAWRASPTLDK-----------SCPFLERVYREDVGPCLDFTVQELSALVRTAVEDNTLTIEPVASQTLPAVKVPTVECNNTN------TCALSGLARTCHHRIRLGDSDSHYYISPSSRARITAVCNFFTYIRYIQQGLVR-QDAEPMFWEIMRLRKGMSLAKLGFFPQEA---------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99NH3-1", "uniprot_id": "R3GEF_RAT", "id": "Q99NH3-1", "name": "Guanine nucleotide exchange factor for Rab-3A", "aln": "------------------------------------------------------------------------------------------------------------------MWSGPPQ--QDEGLP----------------------VGLSAISVPWKNLGPSKGNRKSPGGLVEASASWEEAGGEEHPAAAPLD---------------------------------------------------------------------------------------------------------------------------------------------------VSRLRS-SSMEIREKGSEFLKEELYKAQKELKLKDEECERLCKVRAQLE------------------QELEELTASLFEEAHKMVREANMKQAASEKQLKEAWGKIDMLQAEVTALKTLVITSTPASPNRELHPQLLSP---TKAGPRKGHSRQKSTSS-LCPVVCPTAGHIPTPDKEGKEVDTTLFAEFQAWRASPTLDK-----------NCPFLERVYREDVGPCLDFTVQELSALVRTAVEDNTLTIEPVASQTLP-----NVECNNTN------TCALSGLARTCHHRIRLGDSDGHYYISPSSRARITAVCNFFTYVRYIQQGLVR-QDAEPMFWEIMRLRKGMSLAKLGFFPQEA---------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TBN0-1", "uniprot_id": "R3GEF_HUMAN", "id": "Q8TBN0-1", "name": "Guanine nucleotide exchange factor for Rab-3A", "aln": "------------------------------------------------------------------------------------------------------------------MWSGPPQ--PDQGLP----------------------PPLAAVPVPWKSTDPCQGHRESPGALVETSAG-EEAQGQEGPAAAQLD---------------------------------------------------------------------------------------------------------------------------------------------------VLRLRS-SSMEIREKGSEFLKEELHRAQKELKLKDEECERLSKVREQLE------------------QELEELTASLFEEAHKMVREANMKQAASEKQLKEARGKIDMLQAEVTALKTLVITSTPASPNRELHPQLLSP---TKAGPRKGHSRHKSTSSTLCPAVCPAAGHTLTPDREGKEVDTILFAEFQAWRESPTLDK-----------TCPFLERVYREDVGPCLDFTMQELSVLVRAAVEDNTLTIEPVASQTLPTVKVAEVDCSSTN------TCALSGLTRTCRHRIRLGDSKSHYYISPSSRARITAVCNFFTYIRYIQQGLVR-QDAEPMFWEIMRLRKEMSLAKLGFFPQEA---------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PH17-1", "uniprot_id": "A0A8M9PH17_DANRE", "id": "A0A8M9PH17-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------MDAFEGLHQVQLSSSPPTAPGYE------------VLLTRHSGIAVYSSPVFFSRGEIAEHHHHHHHHHTAEEERCPVGRLVDLEPEPSPRLEGDDGGRRE-----------------------------------------------------------------------------------------------------------------KKPPDEAGADRREAYNMSRLRS-SSLEIKEKGTEFLREQLDAAQKELKLKDEECERLSHVRNQLE------------------QELEELTASLFEEAHKMVREANVKQAAAEKQLKEAQGKIDVLQAEVSALKTLVLTSTPSSPNRQLHPQLLSPGSSRASSRPFGHTRNKSASGALQTEPTNPE---KDTVHHDRELDSVLFAEFLSWKECPNLER-----------SSAFISRVYREDIGPCLSFTSAELSQSVQRCVENNSLTIEPVITSSLPTDKNIHQGGTNGCWTPIETKCALSGLTRPCRHRIKLGDKENYYYISLSSRARITAVCNFFTYIRYIQQGLVR-QDVQQMFWEVMRLRREMSVAKLGFFHTEHS--------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P17065-1", "uniprot_id": "SEC2_YEAST", "id": "P17065-1", "name": "Rab guanine nucleotide exchange factor SEC2", "aln": "MDASEEAKRVSIQVTSLSTQLIESVDKQSHLEEQLNKSLKTIASQKAAIENYNQLKEDYNTLKRELSDRDDEVKRLREDIAKENELRTKAEEEADKLNKEVEDLTASLFDEANNMVADARKEKYAIEILNKRLTEQLREKDTLLDTLTLQLKNLKKVMHSLDNESTVTNNSNRYSTILSDSATSSSTSLNKVPTSYSLASQDIYSGIVYSPSISSIRYDISLYNEFLKFVAALPRCENIKATSTESKLIRRLVNDEIQPILKIDNASGIGWLVKKTLLSLIIDGLVVVEPLSGVNATYQIGYNSSSPAKQATSNMPKMFKFPLDSPPVAVHAACSFCGESRDDIIEHARMYILKTLHKTDDGKEQVTNTYPLCHWCLLKLRQTCEIFAFLRSLKVGAWHLEKLTTQNITKEDLEKFSEVTKHTKRDGRVSSQDKKTKRLSFMAGLGINSSTKNKPKMEIFSSETNAKPGQPTTNIQRAWLQLCKLRCILHWTHIGIWAVDDSISSKIGPLVEDDSDEDQNDAISVRLQDKALWKQDAKRPFSSSSAEESQKSDAFDFESGDMENEITGESSSDESSSDGSSTDNSTADSSSEDESSLADSTTSSADSSSPESIDNGEGDDTVTKDDKSSIKSANNNEENSDCGDKKGRSIIKKKAPQRKIQKKKLLQDLDDLEEQFREESAIDQTEFENAESNVKQNISSKRASSGDENSKKDNNEKTLKTNLTIGDKTQEQIGENSPSSGLHASSSNDDNFDDAQEQQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . . *. *: . :. :.* * : : .: :.: :: : *: : * .. : : *: : :* . . *:: :. ..* *. : : * *: : .. . . : ..: *. . . .:: :: .. : :. ... **.. :. . * ::: : : : : . . : :* . . . :. : ", "identical_positions": 18, "similar_positions": 90, "identity": "2.37%" }, { "cls_id": "homologset.agr.SGD:S000005217", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2Y1-1", "uniprot_id": "TIM_RAT", "id": "Q9Z2Y1-1", "name": "Protein timeless homolog", "aln": "MDLYMMNCELLATCSALGYLEGGTYHKEPDCLESVKDLIRYLRHEDETR-DVRQQLGAAQILQSDLLPILTQHRQDKPLFDAVIRLMVNLTQPALLCFGS--VPKDPTVRHHFLQVLTYLQAYKEAFASEKAFGVLSETLYELLQLGWEDRQEEDNLLIERILLLVRNILHVPAN-----LEQEKRIDDDASIHDRLLWAIHLSGMDDLLLFLSSSSAEQQWSLHVLEIISLMFRDQKP---EQLAGVGQGRLAQERSTDLAELEVLRQRE--------VAEKRARALQRGNRHSRFGG---SYVVQGLKSIGERDVVFHKGLHNLQNYSSDLGK----------------QPRRVPKRRQAAQELSVHRRSVLNVRLFLRDFCSEFLENCYNPLMGAVKDHLLR-EKAQQHDETYYMWAMAFFMAFNRAAAFRPGFVSETLSIRTFHFVEQNLTNYYEMMLTDRKEAASWARRMHLALKA------YQELLATVNEMDMCPDD-AVRESSRIIKNN--------------IFYMMEYRELFLALFRKFDERYHPRSFLCDLVETTHLFLKMLERFCRSRGNLMVQNKRKKR-KKKKK----AQEQGVAFS---RSPEELQAMWSALAERLLQCAQEPELSVDS--IIPFDAASEVPVE----EQRVEAMVRIQDCLVAGQAPQALALLRSAREVWPEGNVFGSPVISPGEEMQLLKQILSAT---------LPRQQEPVEGDAEEEDEEEEEEEEEELQVVQVSEKE-------FKFLDYLKRFACSTIVRAYVLLLRSYRQNSAHTNHCIAKMLHRLAHDLGMEALLFQLSLFCLFNQLLSDPAAAAYKELVTFAKYILGKFFALAAVNQKAFVELLFWKNTSVVREMTQGYGSLDSGSCSHRAPVWSSEEEAQLQELYLAHKDVE--GQDVVETILAHLKAVPRTRKQVIHHLVRMG-------LADSVKDFQ-RKGTQ--IVLWTEDQELELQRLFEEFQDSDDVLGHIMKNITAKRSRARVVDKLLALGLVSERRQLHKKRR---KKLAPSCMQNGEESQRDAWQEDPEEEEEKEGLPESEGEENEEDLLAGQVQGSSSLSAENLRQSLCQDGLSAPLLWLQSSLIRAADDREEDG-----CSQAIPLVPLT-EENEEAMENKQFQHLLRKLGIRAPCSGQETFWRIPAKLSSTQLRRVAASLSERENKE------EREEEPEPNPGVPGEQSPSE----EHQVRAPRALLSARKRKAGLVFPKEE-ATGEEEWKSVPKKQ-------------------------------------------------------------------------------------QLLDSDEED----TDDERGGQAAVSGTLRIHKEKRFLVEDEDEDY--------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R1X4-1", "uniprot_id": "TIM_MOUSE", "id": "Q9R1X4-1", "name": "Protein timeless homolog", "aln": "MDLYMMNCELLATCSALGYLEGGTYHKEPDCLESVKDLIRYLRHEDETR-DVRQQLGAAQILQSDLLPILTQHRQDKPLFDAVIRLMVNLTQPALLCFGS--VPKDSSVRHHFLQVLTYLQAYKEAFASEKAFGVLSETLYELLQLGWEDRQEEDNLLIERILLLVRNILHVPAN-----LEQEKSIDDDASIHDRLLWAIHLSGMDDLLLFLSSSSAEQQWSLHVLEIISLMFRDQTP---EQLAGVGQGRLAQERSTDVAELEVLRQRE--------MAEKRARALQRGNRHSRFGG---SYIVQGLKSIGEKDVVFHKGLHNLQNYSSDLGK----------------QPRRVPKRRQAAQELSVHRRSVLNVRLFLRDFCSEFLENCYNPLMGAVKDHLLR-ERAQQHDETYYMWAMAFFMAFNRAATFRPGLVSETLSIRTFHFVEQNLTNYYEMMLTDRKEAASWARRMHLALKA------YQELLATVNEMDMCPDE-AVRESSRIIKNN--------------IFYMMEYRELFLALFRKFDERYHPRSFLRDLVETTHLFLKMLERFCRSRGNLMVQNKRKKR-KKKKK----VQDQGVAFS---QSPGELEAMWPALAEQLLQCAQDPELSVDP--VVPFDAASEVPVE----EQRVEAMVRIQDCLTAGQAPQALALLRSAREVWPEGNAFGSPVISPGEEMQLLKQILSTP---------LPRQQEPEEGDAEEE---EEEEEEEELQVVQVSEKE-------FNFLEYLKRFASSTIVRAYVLLLRSYRQNSAHTNHCIAKMLHRLAHGLGMEALLFQLSLFCLFNRLLSDPAAAAYKELVTFAKYIIGKFFALAAVNQKAFVELLFWKNTAVVREMTQGYGSLDSGSSSHRAPLWSPEEEAQLQELYLAHKDVE--GQDVVETILAHLKVVPRTRKQVIHHLVRMG-------LADSVKEFQKRKGTQ--IVLWTEDQELELQRLFEEFRDSDDVLGQIMKNITAKRSRARVVDKLLALGLVSERRQLYKKRR---KKLAPSCMQNGEKSPRDPWQEDPEEEDEHLPEDESEDEESEEGLPSGQGQGSSSLSAENLGESLRQEGLSAPLLWLQSSLIRAANDREEDG-----CSQAIPLVPLT-EENEEAMENEQFQHLLRKLGIRPPSSGQETFWRIPAKLSSTQLRRVAASLSQQENEE------EREEEPEP--GVPGEQGPSE----EHRTEALRALLSARKRKAGLGPTEEE-ATGEEEWNSAPKKR-------------------------------------------------------------------------------------QLLDSDEE------EDDEGRRQAVSGTPRVHRKKRFQIEDEDD----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UNS1-1", "uniprot_id": "TIM_HUMAN", "id": "Q9UNS1-1", "name": "Protein timeless homolog", "aln": "MDLHMMNCELLATCSALGYLEGDTYHKEPDCLESVKDLIRYLRHEDETR-DVRQQLGAAQILQSDLLPILTQHHQDKPLFDAVIRLMVNLTQPALLCFGN--LPKEPSFRHHFLQVLTYLQAYKEAFASEKAFGVLSETLYELLQLGWEERQEEDNLLIERILLLVRNILHVPAD-----LDQEKKIDDDASAHDQLLWAIHLSGLDDLLLFLASSSAEEQWSLHVLEIVSLMFRDQNP---EQLAGVGQGRLAQERSADFAELEVLRQRE--------MAEKKTRALQRGNRHSRFGG---SYIVQGLKSIGERDLIFHKGLHNLRNYSSDLGK----------------QPKKVPKRRQAARELSIQRRSALNVRLFLRDFCSEFLENCYNRLMGSVKDHLLR-EKAQQHDETYYMWALAFFMAFNRAASFRPGLVSETLSVRTFHFIEQNLTNYYEMMLTDRKEAASWARRMHLALKA------YQELLATVNEMDISPDE-AVRESSRIIKNN--------------IFYVMEYRELFLALFRKFDERCQPRSFLRDLVETTHLFLKMLERFCRSRGNLVVQNKQKKRRKKKKK----VLDQAIVSGNVPSSPEEVEAVWPALAEQLQCCAQNSELSMDS--VVPFDAASEVPVE----EQRAEAMVRIQDCLLAGQAPQALTLLRSAREVWPEGDVFGSQDISPEEEIQLLKQILSAP---------LPRQQGPEERGAEEE-EEEEEEEEEELQVVQVSEKE-------FNFLDYLKRFACSTVVRAYVLLLRSYQQNSAHTNHCIVKMLHRLAHDLKMEALLFQLSVFCLFNRLLSDPAAGAYKELVTFAKYILGKFFALAAVNQKAFVELLFWKNTAVVREMTEGYGSLDDRSSSRRAPTWSPEEEAHLRELYLANKDVE--GQDVVEAILAHLNTVPRTRKQIIHHLVQMG-------LADSVKDFQ-RKGTH--IVLWTGDQELELQRLFEEFRDSDDVLGHIMKNITAKRSRARIVDKLLALGLVAERRELYKKRQ---KKLASSILPNGAESLKDFCQEDLEEE-ENLPEEDSEEEE-EGGSEAEQVQGSLVLSNENLGQSLHQEGFSIPLLWLQNCLIRAADDREEDG-----CSQAVPLVPLT-EENEEAMENEQFQQLLRKLGVRPPASGQETFWRIPAKLSPTQLRRAAASLSQPEEEQ------KLQPELQP--KVPGEQGSDEEHCKEHRAQALRALLLAHKKKAGLASPEEEDAVGKEPLKAAPKKR-------------------------------------------------------------------------------------QLLDSDEEQ----EEDEGRNRAPELGAPGIQKKKRYQIEDDEDD---------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8INH7-1", "uniprot_id": "Q8INH7_DROME", "id": "Q8INH7-1", "name": "", "aln": "--MSILLADIDATCAALGYSDGQKYQAEPDAAEGLKHLIWILRRDLDNH-EYRRHLGRSKVLQTDLVYMLPDYVHHEELSDLLIRLLVILTNPTLLLYREG-APKDNHGRKVFMELIDILQGYKAAFAKDKVWSALFEKLKQALEIAFAIRSEEQNLLIERILVLVRNVLQVPAN-----PEAECRADNDASLHDQVIWALHQTGMLDLVLFVISSPDEEQFHLHGLEIVCLLFREQSA---ESLADASLQRSLSEKQRDQQELLAARRRE--------RARRQARPPP--GRHSRFGG---TYVIRNMKSVSDRDVICHQALERVSSIDFDREK----------------QQQKRS-HRHIQEEAQVTRRSAFTVRLCLREYCIEVLRSAYNTLVRQVRRVLERNAGSSSHDDSYLLWAIRFFMEFNRLSGLQLQLVSESLSVQCFHWVLTRMQHDMDMIVSDKKQARLWAKRLHVALLT------FRELLQSLLALQKLKDDNNARALFDMLLNN--------------VCYVLEYRETVLHLLMNYNEAHSTKVFLRDVVETANVFIKMMERFCQDSVVVQDKKRGRGASRKKKQ----AATKSKPPAAPQPTEEELSSKWAELATEVCSLLSTELEMPEDEQPLPFDAASEKSID----DQREDCMIRINKLLRSEKLDQAIALLRAAREVWPENEVFGAISAAPEDELLLLREIFMSN---------ITTVESEDKENEKDQKQDEYEDEDDDLDNEEYEEQDNGLTEKTFKFDDFARRLLNPKIVRACTLVLSDWADIPTRSLKAAVTILHRIAYGCKCAGMLFQAKLFRIFQQVFSVERDVHQEELRRLAIFVVRKFVEVAPTNPKIYAELLFYKGIREANELESGYCDAYEAGTKG---AWTEEQESELRFLFEENQRNPETDKDVIDWILDNLVDKTRNRRTVLKKLKELG-------LLFKAPTKRSTKSAQSGKNVWQPEEDDELRSLYDQHRIEPDCLERLVNEFAERRSKQQIIKRMLQIHLIADKSEILPAKKGRGKDKPKKDVEMEGEGDEFDFAEEPMFEDQGYKKPKSKPKKVQKRQMVRTPLDVGTIR--ALIGQVDSEKYQSAIEWLQECLQDASEDTEEAVE----DDDGVPLLPLM-ENQKNAMEDGDFQKVLVALGMQPPISGMEAYWRIPIYLNSADLILRSKILAGEEVDA------EPEDEAADDEDGEEAEESDEEEDFLEKHSRQRKENIATQQQRKLDSLMFNQSDDETEQRAPPKAKDKPKASEKKAKRKVKGKAKESKDCNDDGTDKAELEKPNTDDLFNQLRAKRATKIKLSDMALNESTNAAQEADDDAFNFNSEDYRARLLELEDEEQNSKDADENGGDKENITNKSLQRARRVNVIDSDSDNDDDGALPADKTNKRPRSDDDGDSGHMDANAEEDSDEEANFLARKKPAKVDGEPAKRRRLAIIDDDDEDDF----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P49021-4", "uniprot_id": "TIM_DROME", "id": "P49021-4", "name": "Protein timeless", "aln": "MDWLLATPQLYSAFSSLGCLEGDTYVVNPNALAILEEINYKLTYEDQTLRTFRRAIGFGQNVRSDLIPLLEN-AKDDAVLESVIRILVNLTVPVECLFSVDVMYRTDVGRHTIFELNKLLYTSKEAFTEARSTKSVVEYMKHILESDPKLSPHKCDQINN-CLLLLRNILHIPETHAHCVMPMMQSMPHGISMQNTILWNLFIQSIDKLLLYLMTCPQRAFWGVTMVQLIALIYKDQHVSTLQKLLSLWFEASLSESSEDNESNTSPPKQGSGDSSPMLTSDPTSDSSDNGSNGRGMGGGMREGTAATLQEVSRKGQEYQNAMARVPADKPDGSEEASDMTGNDSEQPGSPEQSQPAGESMDDGDYEDQRHRQLNEHGEEDEDEDEVEEEEYLQLGPASEPLNLTQQPADKVNNTTNPTSSAPQGCLGNEPFKPPPPLPVRASTSAHAQMQKFNESSYASHVSAVKLGQKSPHAGQLQLTKGKCCPQKRECPSSQSELSDCGYGTQVENQESISTSSNDDDGPQGKPQHQKPPCNTKPRNKPRTIMSPMDKKELRRKKLVKRSKSSLINMKGLVQHTPTDDDISNLLKEFTVDFLLKGYSYLVEELHMQLLSNAKVPIDTSHFFWLVTYFLKFAAQLELDMEHIDTILTYDVLSYLTYEGVSLCEQLELNARQEGSDLKPYLRRMHLVVTAIREFLQAIDTYNKVTHLNEDDKAHLRQLQLQISEMSDLRCLFVLLLRRFNPSIHSKQYLQDLVVTNHILLLILDSSAKLGGCQTIRLSEHITQFATLEVMHYYGILLEDFNNNGEFVNDCIFTMMHHIGGDLGQIGVLFQPIILKTYSRIWEADYELC-DDWSDLIEYVIHKFMNTPPKSPLTIPTTSLTEMTKEHNQEHTVCSWSQEEMDTLYWYYVQSKKNNDIVGKIVKLFSNNGNKLKTRISIIQQLLQQDIITLLEYDDLMKFEDAEYQRTLLTTPTSATTESGIEIKECAYGKPSDDVQILLDLIIKENKAQHLLWLQRILIECCFVKLTLRSGLKVPEGDHIMEPVAYHCICKQKSIPVVQWNNEQSTTMLYQPFVLLLHKLGIQLPADAGSIFARIPDYWTPETMYGLAKKLGPLDKLNLKFDASELEDATASSPSRYHHTGPRNSLSSVSSLDVDLG-DTEELALIPEVDAAVEKAHAMASTPSPSEIFAVPKTKHCNSIIRYTPDPTPPVPNWL------QLVMRSKCNHRTGPSGDPSDCIGSSSTTVDDEGFGKSISAATSQAASTSMSTVNPTTTLSLNMLN-------------------------------------------------------------------------------------TFMGSHNENS---SSSGCGGTVSSLSMVALMSTGAAGGGGNTSGLEMDVDASMKSSFERLEVNGSHFSRANNLDQEYSAMVASVYEKEKELNSDNVSLASDLTRMYVSDEDDRLERTEIRVPHYH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53840-1", "uniprot_id": "TOF1_YEAST", "id": "P53840-1", "name": "Topoisomerase 1-associated factor 1", "aln": "---------------MSADLQQGTTNAADFSLTVLRARIALLATAIGGPDYTSQIDPPPYKLGDDCLACLKDLKRWFKLVDDQQKRWDVAMAVAEYRILTD-------------DLLPILIDWENKCSLAAKLAKNNPDHEEFRN---KAYYDKIALNCLQLLVLMTWPLIVTEQ-----SSSNQITLYGELKKHQLVYKKTILSMESGKVLR----AAIRLALDVIKIDRLSRTPRDN----MVLKLVLNFFRNVIAIEPGEFTINTKKS--------MPKKGITSIDTLPPNVSMDDISLNTVISSFHKNKVFGFLLTLTSSLSKEFDQDFIN---------------IPLLEIMFYFTKDVNQELLFPRQFETGTHSKVVNKNESSSANNIVTSAGFELSKLLQKEHQMRKNVIKHTSARHSRFGGLLSIQTP-DKTRLTVSGSQALVDEKIALQKLDDSKKWNKRIIKKHQSVAAEG-----LPNSLLNSQTGKAIFFTE-SNGKHFKEFINN----------------FIDSGFNILLHSVTNYFTTEQDRMVTLEQVEY-LLFFAWFVKYQLLRSKIDNSADIKQVSEALKEVTFILVSSLLRSAYDLKNWTVTHAGMIAFNELLNLVSRTKAAQEEDSTDIEFIVSRLFSDE------RIQLLSNLPKIGSKYSLQFMKSCIELTHSVLKVLEQYSDDKTLVIEGKSRRQKKFNIS-----------------EGDITKLIEEENVDRDEALDILTSSLRS-----IEVNFQKVQANYMTEPVIETYINFLERFRELEDDSIKKVFSFFHRVFVQAKEQALLFRFDLIILLREMLSPDGLDRMSRSRKYVSQFSDYFLARLKKRLKKSPAWFVGLLFPPLHNSEVGFYQRYGEYNVLNNESMYAAPASQFKPIPDEEALPPSILLDMKYGVLVSTLLDDGKTELLDQLLKHIT------HTLDIFKSWLTVNVNAGKETVNPPNEYFTLTGVLNNDPIFKDKDYRALLLLIGYSIPRKINEPCFLPGTVEVSDLTVSCELVKKYLSTPFETPNGLPSSSYLLRVRSEKDSFSHNEQDGWEGDDDYDYNDPYIVPDDQILSKSDAAYFKDLDNNASDKLKGTKFSKGIARSKKKDKRKRRKGEAKTNLPMFGDQDDERPQTVRERHGVFSKEFISDSEDDEDLMNPIFFENETYMRWLLDKNNGQLTEDRYIQFAKFAAERMNNGGVVTGDYTSLFGGSIPSIESIRATESSSFAPDKSLISLASHVASEMSIFDVNNNNN------------------------------------------------------------------------------------NQLSDDDVNS--ESRNSLGSSQPSNSQNMFQSEVYSRKESTKRSLEASAADESDEDEEAIRLFGKKSRVVLSQGDSDD-----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . :. * : : * : * : : : : : . :: * : : . : .: *:*: * :. . :. ::: .: . : : ::: * : : . : . :: . . :.. ::. . . * : . : . : : . : . .. : :. : : : : : .. : .. . : . : . : : : : :. : * . : . : : . . : : : . : :.. : :. : :: : . . : : : . ..: . . ::. .* : : . .::*:: .:**: :: .: . . . *. . .: .: . :: . * .: . . : : : :: . . . . . .. . . : : : :. . . . * : : : . .. . : . . : .: . . . ", "identical_positions": 17, "similar_positions": 201, "identity": "1.14%" }, { "cls_id": "homologset.agr.SGD:S000005218", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8J8XIM5-1", "uniprot_id": "A0A8J8XIM5_RAT", "id": "A0A8J8XIM5-1", "name": "Glyoxylate reductase/hydroxypyruvate reductase", "aln": "-----------ARLVNVCSCGSCETRATHEGVRHW-PFAGPGQGCARPGHRVSARVGVGSAAEPLARCPVHPTSDTPAAALGRSCEVEQWNSDDPIPSKDLEQGVAGAYGLLCRLSDRVDKKLLDAAGANLRVISTLSVGVDHLALDEIKKRGIRVGYTPGVLTDATAELAVSLLLTTCRRLPEAIEEVKNGGWSSWSPLW--MCGYGLSESTVGIVGLGRIGQAIARRLKPFGVQRFLYTGRQPRP-QEAAEFQAEFVPIAQLAAESDFIVVSCSLTPATRGLCNKDFFQKMKNTAVFINISRGDVVNQEDLYQALASGQIAAAGLDVTTPEPLPPSHPLLTLKNCVILPHIGSATYKTRNTMSLLAAN------------NLLAGLRGEPMPSELKL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91Z53-1", "uniprot_id": "GRHPR_MOUSE", "id": "Q91Z53-1", "name": "Glyoxylate reductase/hydroxypyruvate reductase", "aln": "--------MKPARLMKVFVTG---------------PLPAEG------------RAALAQAAD---------------------CEVEQWNSDDPIPRKDLEQGVVGAHGLLCRLSDRVDKKLLDAAGANLRVISTLSVGVDHLALDEIKKRGIRVGYTPGVLTDATAELAVSLLLTTCRRLPEAIEEVKNGGWSSWSPLW--MCGYGLSQSTVGIVGLGRIGQAIARRLKPFGVQRFLYTGRQPRP-QEAAEFQAEFVPIAQLAAESDFIVVSCSLTPDTMGLCSKDFFQKMKNTAIFINISRGDVVNQEDLYQALASGQIAAAGLDVTTPEPLPPSHPLLTLKNCVILPHIGSATYKTRNTMSLLAAN------------NLLAGLRGEAMPSELKL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBQ7-1", "uniprot_id": "GRHPR_HUMAN", "id": "Q9UBQ7-1", "name": "Glyoxylate reductase/hydroxypyruvate reductase", "aln": "--------MRPVRLMKVFVTR---------------RIPAEG------------RVALARAAD---------------------CEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLW--LCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRP-EEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAAN------------NLLAGLRGEPMPSELKL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QCX2-1", "uniprot_id": "E9QCX2_DANRE", "id": "E9QCX2-1", "name": "Glyoxylate reductase/hydroxypyruvate reductase", "aln": "MWCSRTALGRLQRIAPCTVTGHHRAMSALPKVYVTRRIPPDG------------LDILRKSGQ---------------------VQFELWDSDDPVPRVELLNKVKGCDGILCVLTEKIDAQLLDVAGPNLKVLSTMSVGYDHLSLEELKKRGIRVGYTPEVLTDAVAELTVALLLATSRRLIEATHEAKTGGWGTWRTMW--LCGHELANSTVGILGLGRIGVAIAERLKPFKVKKFIYTDVEPRT-ELANMINAEYVSLDELAKQSDFLAICCALTPETHGICNWNLFSKMKKNAIFINTSRGGVVNQEDLYEALSTGLIAGAGLDVTTPEPLPTHHPLYTLKNCVILPHIASASYTTRNAMSALAAN------------NLLAGLRGEAMPKELKL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8I725-1", "uniprot_id": "Q8I725_DROME", "id": "Q8I725-1", "name": "Glyoxylate reductase/hydroxypyruvate reductase", "aln": "----MPPRLPFGQVRNLLIQGHIIRRMSSQHKVYVTRPDVDD----------SGLELLRKS-----------------------CQVSTWHETNPVPRSELIRVVAGKDALYCALTDKVDKEVLDAAGPQLKCVATISVGYDHIDVEECRKRGIRVGFTPDVLTDATAELTLALLLATNRRLFEANKQVYNGGWKSWAPMW--MCGQGLKGSRVGLLGFGRIGQEIAARIVPFKPTEITYTTRSLRP-KEAAAVNARHVDFDEMLRESDLIVVCCALTPETKEIFNATAFQKMKPNCILINTARGGVVDQKALYEALKTKRILAAGLDVTTPEPLPIDDPLLKLDNVVILPHIGSADIETRKEMSRITAR------------NILAALAGDKMVAEVEL--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VII9-1", "uniprot_id": "Q9VII9_DROME", "id": "Q9VII9-1", "name": "Glyoxylate reductase/hydroxypyruvate reductase", "aln": "-------MSRATRAFKVLISHP--------------NVPAPA------------LELLRSR-----------------------GAETIICQSVPPSRDEILQKVPGVDAIYWAHYQPLNAGILDAAGSQLRCVSTMSSGIDFVDIPEFQKRGIPLGHTPGVVKNAVADLAIGLMIAAGRHFHAGRTEIERSQWKIEQINW--MMGQEIRDSVIGFFGFGGISQAIAKRLQCWDVAKIIYHTRTRK--ENDGDFKAEHVSFEQLLQESDFLVVAAPLTNETREKFNGKAFNLMKRSSVFVNVARGGLVNQTDLHDALTNGTISAAGLDVTTPEPLPANSPLLNVPNCVILPHMGTQTMKTTIEMGLLAAN------------NILNAIEGKPMIRPAY---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8INU6-1", "uniprot_id": "Q8INU6_DROME", "id": "Q8INU6-1", "name": "Glyoxylate reductase/hydroxypyruvate reductase", "aln": "-------MS-TTKPFKVLIAHT--------------DVPPEG------------IEILKEQ-----------------------CEILQVINEPPKNRPEILEKIRGAHAVIWGGRDILNAEILDAAGPQLKAVSTMSSGINNVDVPELKKRGIPLGSTPAMLTVAVADLTVGLLIAAARRFQEGRRKIDSDKWDKDHLNW--MLGQDIRDSTVGFYGFGGIGQAVAKRLMGFDIKRMLYTTRNRVSQDIEERFNAKKVDFETLLAESDFLIIASPLTKETLGLFNATVFNKMKETAVLVNVGRGKIVNQDDLYEALKSNRIFAAGLDVMDPEPLPSNDKLLTLDNVVVTPHVGYATRRTRVDAANLASR------------NVLKGLAGEPMLSPAY---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53839-1", "uniprot_id": "GOR1_YEAST", "id": "P53839-1", "name": "Glyoxylate reductase 1", "aln": "-------MSKKPIVLKLGKDAFG--------------DQAWG-----------ELEKIADVITIP----------------ESTTREQFLREVKDPQNKLSQVQVITRTARSVKNTGRFDEELALALPSSVVAVCHTGAGYDQIDVEPFKKRHIQVANVPDLVSNATADTHVFLLLGALRNFGIGNRRLIEGNWPEAGPACGSPFGYDPEGKTVGILGLGRIGRCILERLKPFGFENFIYHNRHQLP--SEEEHGCEYVGFEEFLKRSDIVSVNVPLNHNTHHLINAETIEKMKDGVVIVNTARGAVIDEQAMTDALRSGKIRSAGLDVFEYEPKIS-KELLSMSQVLGLPHMGTHSVETRKKMEELVVENAKNVILTGKVLTIVPELQNEDWPNESKPLV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . .: : . ..: :. . * : : : :** * :. .* ::. :.*: : *:: : *.: . . . * * . :*: *:* *. : *: : .: * .. * : .**:: : .*. * . :. ** :::* .** :::: : :** . * .***** ** * .: : : **:. * :. . .:: : .. ", "identical_positions": 40, "similar_positions": 85, "identity": "9.98%" }, { "cls_id": "homologset.agr.SGD:S000005219", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23348-1", "uniprot_id": "B3A3_RAT", "id": "P23348-1", "name": "Anion exchange protein 3", "aln": "---MANGVIPPPGGPSPLPQVRVPLEEPPLGPDVEEEDDDLGKTLAVSRFGDLISKTPAWDPEKPSRSYSERDFEFHRHTSHHTHHPLSARLPPPHKLRRLPPTSARHARRKRKKEKTSAPPSEGTPPIQEEGGAGAEEEEEEEEEEEGESE-AEPVEPPPPGPPQ-------KAKFSIGSDEDDSPG--LSIKAPCAKALPSVGLPSDQSPQRSGSSPSP-------RARASRISTE---KSRPWS--------PSASYDLRERLCPGSALGNPG-PEQRVPTDEAEAQMLGSADLDDMKSHRLEDNPGVRRHLVKKPSRIQGGRGSPSGLAPILRRKKKKKKLDRRPHE-------------------VFVELNELMLD-RSQEPHWRETA------------------------RWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTIAQGAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDR--ASVLRTLLLKH--------------------------------SHPNDDKDSG-----------FFPRNPSSSSVNSVLGNHHPTPSHGPDGAVPTMADDLGE-------------------------------------------------------------------------------------------------------------------------------PAPLWPH-----DPDAKEKPLHMPGGDGHRG---------------------KSLKLLEKIPEDAEATVVLVGSVPFLEQPAAAFVRLSEAVLLESVLEVPVPVRFLFVMLGP--SHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLGAISEFLDGSIVIPPSEVEGRDLL-RSVAAFQRELLRKRREREQTKVEMTTRGGYVAPGKELSLEMGGSEAT-----------------------SEDDPLQRTGSVFGGLVRDVKRRYPHYPSDLRDALH------SQCVAAVLFIYFAALSPAITFGGLLGEKTEGLMGVSELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDLEYLTGRVWVGLWLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFHKLYKVFTEHPLLP-------FYPPEEALEP----------------------------------------GLELNSSALPPTEGPPGPRNQPNTALLSLILMLGTFLIAFFLRKFRNSRFLGG--------------------------------------KARRVIGDFGIPISILVMVLVDYS---ITDTYTQKLTVPTGLSVTSPHKRTWFIPPLGSARPFPPWMMVAAAVPALLVLILIFMETQITALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRTAIAPGDK-PQIQEVREQRVTGVLIASLVGLSIVMGAV-LRRIPLAVLFGIFLYMGVTSLSGIQ----------------LSQRLLLIFMPAKHHPEQPYVTKVKTWRMHLFTFIQLGCIALLWVVKSTVASLAFPFLLLLTVPLRRCLLPRLFQDRELQALDSEDAEPNFDE-DGQDE--------------------------------YNELHMPV---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16283-1", "uniprot_id": "B3A3_MOUSE", "id": "P16283-1", "name": "Anion exchange protein 3", "aln": "---MANGVIPPPGGASPLPQVRVPLEEPPLGPDVEEEDDDLGKTLAVSRFGDLISKTPAWDPEKPSRSYSERDFEFHRHTSHHTHHPLSARLPPPHKLRRPPPTSARHTRRKRKKEKTSAPPSEGTPPIQEEGGAGAEEEEEEEEEEEGESE-AEPVEPLPPGPPQ-------KAKFSIGSDEDDSPG--LPVKAPCAKALPSVGLQSDQSPQRSGSSPSP-------RARASRISTE---KSRPWS--------PSASYDLRERLCPGSALGNPG-PEQRVPTDEAEAQMLGSADLDDMKSHRLEDNPGVRRHLVKKPSRIQGGRGSPSGLAPILRRKKKKKKLDRRPHE-------------------VFVELNELMLD-RSQEPHWRETA------------------------RWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTIAQGAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDR--ASVLRTLLLKH--------------------------------SHPNDDKDSG-----------FFPRNPSSSSVNSVLGNHHPTPSHGPDGAVPTMADDQGE-------------------------------------------------------------------------------------------------------------------------------PAPLWPH-----DPDAKEKPLHMPGGDGHRG---------------------KSLKLLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLSEAVLLESVLEVPVPVRFLFVMLGP--SHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLGAISEFLDGSIVIPPSEVEGRDLL-RSVAAFQRELLRKRREREQTKVEMTTRGGYAAPGKELSLEMGGSEAT-----------------------SEDDPLQRTGSVFGGLVRDVKRRYPHYPSDLRDALH------SQCVAAVLFIYFAALSPAITFGGLLGEKTEGLMGVSELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDLEYLTGRVWVGLWLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFHKLYKVFTEHPLLP-------FYPPDEALET----------------------------------------GLELNSSALPPTEGPPGPRNQPNTALLSLILMLGTFLIAFFLRKFRNSRFLGG--------------------------------------KARRIIGDFGIPISILVMVLVDYS---ITDTYTQKLTVPTGLSVTSPHKRTWFIPPLGSARPFPPWMMVAAAVPALLVLILIFMETQITALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRTAIAPGDK-PQIQEVREQRVTGVLIASLVGLSIVMGAV-LRRIPLAVLFGIFLYMGVTSLSGIQ----------------LSQRLLLIFMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWVVKSTAASLAFPFLLLLTVPLRRCLLPRLFQDRELQALDSEDAEPNFDE-DGQDE--------------------------------YNELHMPV---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48751-1", "uniprot_id": "B3A3_HUMAN", "id": "P48751-1", "name": "Anion exchange protein 3", "aln": "---MANGVIPPPGGASPLPQVRVPLEEPPLSPDVEEEDDDLGKTLAVSRFGDLISKPPAWDPEKPSRSYSERDFEFHRHTSHHTHHPLSARLPPPHKLRRLPPTSARHTRRKRKKEKTSAPPSEGTPPIQEEGGAGVDEEEEEEEEEEGESE-AEPVEPPHSGTPQ-------KAKFSIGSDEDDSPG--LPGRAAVTKPLPSVGPHTDKSPQHSSSSPSP-------RARASRLAGE---KSRPWS--------PSASYDLRERLCPGSALGNPGGPEQQVPTDEAEAQMLGSADLDDMKSHRLEDNPGVRRHLVKKPSRTQGGRGSPSGLAPILRRKKKKKKLDRRPHE-------------------VFVELNELMLD-RSQEPHWRETA------------------------RWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTIAHGAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDR--ASVLRTLLLKH--------------------------------SHPNDDKDSG-----------FFPRNPSSSSMNSVLGNHHPTPSHGPDGAVPTMADDLGE-------------------------------------------------------------------------------------------------------------------------------PAPLWPH-----DPDAKEKPLHMPGGDGHRG---------------------KSLKLLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPVRFLFVMLGP--SHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSIVIPPSEVEGRDLL-RSVAAFQRELLRKRREREQTKVEMTTRGGYTAPGKELSLELGGSEAT-----------------------PEDDPLLRTGSVFGGLVRDVRRRYPHYPSDLRDALH------SQCVAAVLFIYFAALSPAITFGGLLGEKTEGLMGVSELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDLEYLTGRVWVGLWLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFYKLYKVFTEHPLLP-------FYPPEGALEGSLDA------------------------------------GLEPNGSALPPTEGPPSPRNQPNTALLSLILMLGTFFIAFFLRKFRNSRFLGG--------------------------------------KARRIIGDFGIPISILVMVLVDYS---ITDTYTQKLTVPTGLSVTSPDKRSWFIPPLGSARPFPPWMMVAAAVPALLVLILIFMETQITALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRTAIAPGDK-PQIQEVREQRVTGVLIASLVGLSIVMGAV-LRRIPLAVLFGIFLYMGVTSLSGIQ----------------LSQRLLLILMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWVVKSTAASLAFPFLLLLTVPLRHCLLPRLFQDRELQALDSEDAEPNFDE-DGQDE--------------------------------YNELHMPV---------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A096X8J7-1", "uniprot_id": "B3A3_DANRE", "id": "A0A096X8J7-1", "name": "Anion exchange protein 3", "aln": "----------------------------------------------------------------MGRSYNEKDFEYHRHTFHHTHHPLSTHLPP-QRFRKRVLSMDRRRKRKRKKKKTSMPPSDVTPTIHEVDEEEAESEIEGQCQAATPTEPSEELPQLSLGSEEDLAADLPLSSFHMESERPASSEETLPSPASMEEKEETQQPPDGGEHKDISNSFSP-------SPEAASMTTRGWFRRKPVHRLAGA---QRTSYDLRERICIGSMTAMETAVYQKVPTDEAEAQMLASADLDDMKSHRFEDNPGVRRHLVKKSSRCQLPRSSNG--SPPLSSLKRRKRMDKKTHE-------------------VFVELNELIVD-KNQEMRWKERA------------------------RWIKFEEDVEEETDRWGKPHVASLSFRSLLELRRTITHGAIMLDLDQSTLPGIAHLMVETMIISDQIRAEDR--ANVLRALLLKH--------------------------------SHPNDEKE-G-----------LFHRNHSVTSLGSFRHNHN----HVHDTSLPLVSQDHEE-------------------------------------------------------------------------------------------------------------------------------MHDSKAA-----EHD-KEKSLHPIPAEGHAAS--------------------RSLKLLAKIPKDAEATVVLVGCVEFLEKPAMAFVRLNESILLESILEVPVPIRFIFVLLGP--TQTNVDYHEIGRSFSTLMSDKNFHEVAYFADDRQDLLNGINEFLDCSIVIPPSDVEGKDLL-KTVASFQKQMLRKRKERELKKCASTVTGAELET-KDVNIEEQEEEDQ-----------------------FDVDPLKRSGIPFGGLIHDIRRRYPRYISDLKDALD------TQCIAAVIFIYFAALSPTITFGGLLGEKTQGMMGVSELIISTATVGVLFSLLAGQPLLIIGFSGPLLVFEEAFYKFCQAQGFEYLTGRVWIGFWLIFIVLVIVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFSKLIKVFQEHPLMM-------SYTSAAFKHS------------------------------------------DQRGSSVIGEP----ILNQPNTALLSMVLMMGTFFTAFFLRKLRNSRFLGG--------------------------------------KVRRVIGDFGIPISILISVLVDIL---IPDTYTQKLNVPSGFSVTSPDKRGWFISPFGDKQPFPVWMMGASVIPALLVFILIFMETQITTLIVSKKERRLMKGSGFHLDLLLIVTLGAICPLFGLPWLTAATVRSVTHVNALTVMSKATAPGEK-PMIQEVKEQRVTGMCVAILVGLSIVMTDV-LRHIPLAVLFGIFLYMGITSLTGIQ----------------LYERITLMVTPAKHHPDHVYVTKVKTWRMNMFTVIQLLCIVLLWVVKSTVASLAFPFILIMTVPLRRLILTRIFEERELAALDADEDSPNFDE-DGRDE--------------------------------YNEIHMLV---------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13808-1", "uniprot_id": "B3A2_MOUSE", "id": "P13808-1", "name": "Anion exchange protein 2", "aln": "MS---SAPRRPASGADSLHTPEPESLSPGTPGFPEQEE-DELRTLGVERFEEILQEAGSRGGEEPGRSYGEEDFEYHRQSSHHIHHPLSTHLPPDARRRK-----TPQGPGRKPRRRPGASPTGETPTIEE---GEEDEEEASEAEGFR----APPQQPSPATTPS-------AVQFFLQEDEGAERKPERTSPSPPTQTPHQEAAPRASKGAQTGTLVEE----MVAVASATAGGDDGGAAGRPLTKAQPG----HRSYNLQERRRIGSMTGVEQALLPRVPTDESEAQTLATADLDLMKSHRFEDVPGVRRHLVRKNAKGSTQAAREG--REPGPTPRARPRAPHKPHE-------------------VFVELNELLLD-KNQEPQWRETA------------------------RWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTLAHGAVLLDLDQQTLPGVAHQVVEQMVISDQIKAEDR--ANVLRALLLKH--------------------------------SHPSDEKEFS------------FPRNISAGSLGSLLGHHHA---QGTESDPHVTEPLIGG------------------------------------------------------------------------------------------------------------------------------VPETRLEV-----DRERELPPPAPPAGITRSKSK-------------------HELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLGP--SSANMDYHEIGRSISTLMSDKQFHEAAYLADERDDLLTAINAFLDCSVVLPPSEVQGEELL-RSVAHFQRQMLKKREEQG-RLLPPGAGLEPKSAQDKALLQMVEVAGA-----------------------AEDDPLRRTGRPFGGLIRDVRRRYPHYLSDFRDALD------PQCLAAVIFIYFAALSPAITFGGLLGEKTKDLIGVSELIMSTALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFFSFCSSNELEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYETFYKLIKIFQEHPLHG-------CSGSNDSEAG----SS------------------------SSSNMTWATTILVPDNSSASGQSGQEKPRGQPNTALLSLVLMAGTFFIAFFLRKFKNSRFFPG--------------------------------------RIRRVIGDFGVPIAILIMVLVDYS---IEDTYTQKLSVPSGFSVTAPDKRGWVINPLGEKTPFPVWMMVASLLPAVLVFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANALTVMSKAVAPGDK-PKIQEVKEQRVTGLLVALLVGLSMVIGDL-LRQIPLAVLFGIFLYMGVTSLNGIQ----------------FYERLHLLLMPPKHHPDVTYVKKVRTMRMHLFTALQLLCLALLWAVMSTAASLAFPFILILTVPLRMVVLTRIFTEREMKCLDANEAEPVFDECEGVDE--------------------------------YNEMPMPV---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23347-1", "uniprot_id": "B3A2_RAT", "id": "P23347-1", "name": "Anion exchange protein 2", "aln": "MS---SAPRRPASGADSLHTPEPESLSPGTPGFPEQEEEDELRTLGVERFEEILQEAGSRGGEEPGRSYGEEDFEYHRQSSHHIHHPLSTHLPPDARRRK-----TPQGPGRKPRRRPGASPTGETPTIEE---GEEDEDEVGEAEGFR----APPQQPSPASSPS-------AVQFFLQEDEGTDRKAERTSPSPPTQTPHQEAAPRASKGAQTGTLVEE----MVAVASGTAGGDDGGAAGRPLTKAQPG----HRSYNLQERRRIGSMTGVEQALLPRVPTDESEAQTLATADLDLMKSHRFEDVPGVRRHLVRKNAKGSTQAAREG--REPGPTPRARPRAPHKPHE-------------------VFVELNELQLD-KNQEPQWRETA------------------------RWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTLAHGAVLLDLDQQTLPGVAHQVVEQMVISDQIKAEDR--ANVLRALLLKH--------------------------------SHPSDEKEFS------------FPRNISAGSLGSLLGHHHA---QGTESDPHVTEPLIGG------------------------------------------------------------------------------------------------------------------------------VPETRLEV-----DRERELPPPAPPAGITRSKSK-------------------HELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLGP--SSANMDYHEIGRSISTLMSDKQFHEAAYLADERDDLLTAINAFLDCSVVLPPSEVQGEELL-RSVAHFQRQMLKKREEQG-RLLPPGAGLEPKSAQDKALLQMVEVAGA-----------------------AEDDPLRRTGRPFGGLIRDVRRRYPHYLSDFRDALD------PQCLAAVIFIYFAALSPAITFGGLLGEKTQDLIGVSELIMSTALQGVIFCLLGAQPLLVIGFSGPLLVFEEAFFSFCKSNQLEYLVGRVWIGFWLVLLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYETFYKLIKIFQEHPLHG-------CSVSNDSEAD----SS------------------------SN-NMTWAATTLAPDNSSASGQ---ERPRGQPNTALLSLVLMAGTFFIAFFLRKFKNSRFFPG--------------------------------------RIRRVIGDFGVPIAILIMVLVDYS---IEDTYTQKLSVPSGFSVTAPDKRGWVINPLGEKTPFPVWMMVASLLPAVLVFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANALTVMSKAVAPGDK-PKIQEVKEQRVTGLLVALLVGLSMVIGDL-LRQIPLAVLFGIFLYMGVTSLNGIQ----------------FYERLHLLLMPPKHHPDVTYVKKVRTMRMHLFTALQLLCLALLWAVMSTAASLAFPFILILTVPLRMVVLTRIFTEREMKCLDANEAEPVFDECEGVDE--------------------------------YNEMPMPV---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04920-1", "uniprot_id": "B3A2_HUMAN", "id": "P04920-1", "name": "Anion exchange protein 2", "aln": "MS---SAPRRPAKGADSFCTPEPESLGPGTPGFPEQEEDELHRTLGVERFEEILQEAGSRGGEEPGRSYGEEDFEYHRQSSHHIHHPLSTHLPPDARRRK-----TPQGPGRKPRRRPGASPTGETPTIEE---GEEDEDEASEAEGAR----ALTQ-PSPVSTPS-------SVQFFLQEDDSADRKAERTSPSSPAPLPHQEATPRASKGAQAGTQVEEAEAEAVAVASGTAGGDDGGASGRPLPKAQPG----HRSYNLQERRRIGSMTGAEQALLPRVPTDEIEAQTLATADLDLMKSHRFEDVPGVRRHLVRKNAKGSTQSGREG--REPGPTPRARPRAPHKPHE-------------------VFVELNELLLD-KNQEPQWRETA------------------------RWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTLAHGAVLLDLDQQTLPGVAHQVVEQMVISDQIKAEDR--ANVLRALLLKH--------------------------------SHPSDEKDFS------------FPRNISAGSLGSLLGHHHG---QGAESDPHVTEPLMGG------------------------------------------------------------------------------------------------------------------------------VPETRLEV-----ERERELPPPAPPAGITRSKSK-------------------HELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLGP--SSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQGEELL-RSVAHFQRQMLKKREEQG-RLLPTGAGLEPKSAQDKALLQMVEAAGA-----------------------AEDDPLRRTGRPFGGLIRDVRRRYPHYLSDFRDALD------PQCLAAVIFIYFAALSPAITFGGLLGEKTQDLIGVSELIMSTALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFFSFCSSNHLEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYETFYKLVKIFQEHPLHG-------CSASNSSEVD----GG------------------------ENMTWAGARPTLGPGNRSLAGQSGQGKPRGQPNTALLSLVLMAGTFFIAFFLRKFKNSRFFPG--------------------------------------RIRRVIGDFGVPIAILIMVLVDYS---IEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAILVFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANALTVMSKAVAPGDK-PKIQEVKEQRVTGLLVALLVGLSIVIGDL-LRQIPLAVLFGIFLYMGVTSLNGIQ----------------FYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALLWAVMSTAASLAFPFILILTVPLRMVVLTRIFTDREMKCLDANEAEPVFDEREGVDE--------------------------------YNEMPMPV---------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PZ09-1", "uniprot_id": "A0A8M9PZ09_DANRE", "id": "A0A8M9PZ09-1", "name": "Anion exchange protein", "aln": "MSDPQDASDVTSAAGLTRHLPIAVQPPP--QRCDDEDEGDLNKTLGVQRFQQILTPP-QRLPTEQHRTFNEEDFEYHRHTSLHIHHPLSKHLPDGRRKKP-----GRKRKDSG---RRRSSSMGAAPPIDE---DDEDEEADEDSCSQQDREGNVTTTPTPDTDTEDRE----RAQFFVSEDD-PKKNGEVSSHRKPSITSHSKLHTSISIPEDVTGASGR-----RWGRIPPNGRRVSAPCLFPSVSSPDGSCKTGRSYDLQERRRTGNMTGATLSHYQQMPTDESEAKTLATVDLDGIKSHRFEDVPGVRRHLVKKSAKGQVVHIGKD--YKE-FSSRIRTKLDRTPHERRSWPCYMDHRVHRAQQLKVFVELNELLMD-KNQEMHWKETA------------------------RWIKFEEDVEEETERWGKPHVASLSFRSLLELRKTISHGAVLLDLDQKTLPGIAHQVVEQMIISDQIRAHDR--ANVLRALLLKH--------------------------------SHPSDGKEHS-----------LFNRNISATSLGSLISHYHS-TNHIGAPELPATDPLIGGLR---------------------------------------------------------------------------------------------------------------------------NFESRSSVD-----YVEKNEKDSPQFFGLHKTKSK-------------------HELKLLEKIPEDAEATVVLVGCVDFLDQPTMAFVRLKEAVLLESVLEVPIPVRFLFVLLGP--PSANIDYHQIGRSISTLMSDKHFHEAAYLADGRQDLLTAINSFLDCSIVLPPSEVGGDELL-HSIARFQKEMLHKRHEQE-VKLQA---KEPKSPDD-IALQPPLKP--------------------------EDDPLRRTGRLFGGVIRDVRRRYPKYISDFKDALS------PQCMATVIFIYFAALSPAVTFGGLLGEKTDGLIGVSELIISTAVQGMLFCLLGAQPLLIVGFSGPLLVFEEAFYSFCKSNDLEYLTGRMWIGMWLIIIVLLTVAFEGSFLVRFVSRFTQEIFSILISLIFIYETFFKLGKIFMDHPLRS-------CSGPEENATS----LS------------------------TGS------------NDSRSTG--ASQTLNQPNTALLSLVLTSGTFFIAYYLRKFKNSAFFPG--------------------------------------RLRRAIGDFGVPIAISTMVLLDYS---IKDTYTQKLNVPDGFSVTSPDKRGWFIHPLGSDGQFPIWMMGACILPALLVYILIFMETQITTLIVSKKERMLVKGSGFHLDLLIIVVSGGIAALFGLPWLTGATVRSVTHANSLTVMSKAVAPGDK-PRIQEVKEQRVTGFLVALLVGLSIVIGDL-LRQVPIAVLFGIFLYMGVMSLNGIQ----------------LTERMMLLFMPPKYHPDHTYVRKVRTLRMHLFTCLQLVCLAVLWIVMSTAASLAFPFVLVLTVPFRRFLLSRIFSHREIQCLDADDAEPTLDDKDGQDE--------------------------------YTEMQMPV---------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58IQU2-1", "uniprot_id": "A0AC58IQU2_DANRE", "id": "A0AC58IQU2-1", "name": "Anion exchange protein", "aln": "MTDPVTSDQLTNAVDSVVHNPESSSLPVRVSQREEEEEDDLNKSLGVQRFQQILSPT-ARVPGDQHRSYNEKDFEYHRQSSHHIHHPLSKLPGDNRRKKS-----GRKRRRSSSKPHKVCSSPSGALAIEE---GEDEEEEEEEESAE-----NQSVTPAPTTDNDRKD----NVQFFVSDDD-PHVSTPETSDPVP--TRGILIVPTTAVCSEPQDSTST-----EASEAAPASPSTAEHGSIPRVSS--------RSYDLQERRRTGNMTGTEQAKYQRIPTDEYEARTLASADLDGIKSHRFEDVPGVRRHLVRKSTKGQMVHISKD--HKE-RSTRSR-KLDRTPHE-------------------VFVELNELIMD-KNQEMQWRETA------------------------RWIKFEEDVEEETDRWGKPHVASLSFRSLLELRKTIAHGAVLLDLDQKTLPGISHQVVEQMIISDQIKAEDR--ANVLRALLLKHRSTHDPS--------QSLLVSLTRFLPCSPSLSHPSDEKEHIT----------SFPRNISAASLGSLISHHQSSSNHLTIPETSVMEPLMGSSR---------------------------------------------------------------------------------------------------------------------------ASQDSTVHI-----DIDKNEKDSATPIGMHRSKSK-------------------HELKLLEKIPENAEATVVLVGSVDFLEQPTMAFVRLQEAVELDSVLEVPVPVRFLFVLLGP--PSTNMDYHQIGRSISTLMSDKQFHEAAYLADDRQDLLNAINGFLDCSIVLPPSELGGEDLL-RSVAHFQREMLRKREEQG-VALMA---KEPKSLQEKEALLAPFKP--------------------------EDDPLKRTGRLFGGLIRDAQRRYPKYISDFRDALN------PQCMAAVIFIYFAALSPAITFGGLLGEKTEGLLGVSELIVATCVQGVLFCLLGAQPLLIVGFSGPILVFEEAFFSFCKGNNMEYLTGRVWIGFWLIIIVVLMVAFEGSFMVRFVSRFTQEIFSFLISLIFIYETFSKLAKIFQEHPLQR-------CSAVLVDVRN----SS------------------------LNSSMDEVTESPLAVTNSSSQE--MLKVVGEPNTALLSLVLMSGTFLIAFYLRKFKNSAFFPG--------------------------------------RLRRVIGDFGVPIAILIMVLVDYS---VKDTYTQKLSVPRGFSVTSPDKRGWIVNPLGSDGQFPIWMMFASILPALLVFILIFMETQITTLIVSKKERMLVKGSGFHLDLLLIVTLGGTSALFGLPWMAAATVRSVTHANALTVMSKAVAPGDK-PRIQEVKEQRVTGLLVAILVGLSIVIGDL-LRQIPIAVLFGIFLYMGVMSLNGIQ----------------MTERILLLLMPPKYHPDHTYVRKVRTLRMHLFTAIQVVCLAVLWAVMSTVASLAFPFVLIMTVPVKMFLLPRIFSNREMQCLDADDAEPTFDEKEGQDE--------------------------------YTEMHMPV---------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P04919-1", "uniprot_id": "B3AT_MOUSE", "id": "P04919-1", "name": "Band 3 anion transport protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDMRDHEEVLEIPDRDSEEELENIIGQIAYRDLTIPVTEMQDPEALPTEQTATDYVPSSTSTPHP------------SSGQ------------------------------VYVELQELMMDQRNQELQWVEAA------------------------HWIGLEENLRED-GVWGRPHLSYLTFWSLLELQKVFSKGTFLLGLAETSLAGVANHLLDCFIYEDQIRPQDR--EELLRALLLKR--------------------------------SHAEDLGNLE--------------------------------------GVKPAVLTRSGG-------------------------------------------------------------------------------------------------------------------------------ASEPLLP-----HQPSLETQLYCGQAEGGSEGP-------------------STSGTLK-IPPDSETTLVLVGRANFLEKPVLGFVRLKEAVPLED-LVLPEPVGFLLVLLGP--EAPHVDYTQLGRAAATLMTERVFRITASMAHNREELLRSLESFLDCSLVLPPTDAPSEKAL-LNLVPVQKELLRRRYLPS-------PAKPDPNLYNTLDLNGGKGGPG-----------------------DEDDPLRRTGRIFGGLIRDIRRRYPYYLSDITDALS------PQVLAAVIFIYFAALSPAVTFGGLLGEKTRNLMGVSELLISTAVQGILFALLGAQPLLVLGFSGPLLVFEEAFFSFCESNNLEYIVGRAWIGFWLILLVMLVVAFEGSFLVQYISRYTQEIFSFLISLIFIYETFSKLIKIFQDYPLQQ-------TYAP-VVMKP-------------------------------------------------------KPQGPVPNTALFSLVLMAGTFLLAMTLRKFKNSTYFPG--------------------------------------KLRRVIGDFGVPISILIMVLVDSF---IKGTYTQKLSVPDGLKVSNSSARGWVIHPLGLYRLFPTWMMFASVLPALLVFILIFLESQITTLIVSKPERKMIKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKASGPGAA-AQIQEVKEQRISGLLVSVLVGLSILMEPI-LSRIPLAVLFGIFLYMGVTSLSGIQ----------------LFDRILLLFKPPKYHPDVPFVKRVKTWRMHLFTGIQIICLAVLWVVKSTPASLALPFVLILTVPLRRLILPLIFRELELQCLDGDDAKVTFDEENGLDE--------------------------------YDEVPMPV---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23562-1", "uniprot_id": "B3AT_RAT", "id": "P23562-1", "name": "Band 3 anion transport protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDMQDHEKVLEIPDRDSEEELEHVIEQIAYRDLDIPVTEMQESEALPTEQTATDYIPTSTSTSHP------------SSSQ------------------------------VYVELQELMMDQRNQELQWVEAA------------------------HWIGLEENLRED-GVWGRPHLSYLTFWSLLELQKVFSKGTFLLDLAETSLAGVANKLLDSFIYEDQIRPQDR--DELLRALLLKR--------------------------------SHAEDLKDLE--------------------------------------GVKPAVLTRSGA-------------------------------------------------------------------------------------------------------------------------------PSEPLLP-----HQPSLETKLYCAQAEGGSEEP-------------------SPSGILK-IPPNSETTLVLVGRASFLVKPVLGFVRLKEAVPLED-LVLPEPVSFLLVLLGP--EAPHIDYTQLGRAAATLMTERVFRVTASLAQSRGELLSSLDSFLDCSLVLPPTEAPSEKAL-LNLVPVQKELLRKRYLPR-------PAKPDPNLYEALD--GGKEGPG-----------------------DEDDPLRRTGRIFGGLIRDIRRRYPYYLSDITDALS------PQVLAAVIFIYFAALSPAVTFGGLLGEKTRNLMGVSELLISTAVQGILFALLGAQPLLVLGFSGPLLVFEEAFYSFCESNNLEYIVGRAWIGFWLILLVVLVVAFEGSFLVQYISRYTQEIFSFLISLIFIYETFSKLIKIFQDYPLQE-------SYAP-VVMKP-------------------------------------------------------KPQGPVPNTALLSLVLMVGTFLLAMMLRKFKNSTYFPG--------------------------------------KLRRVIGDFGVPISILIMVLVDTF---IKNTYTQKLSVPDGLKVSNSSARGWVIHPLGLYNHFPKWMMFASVLPALLVFILIFLESQITTLIVSKPERKMIKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKASGPGAA-AQIQEVKEQRISGLLVSVLVGLSILMEPI-LSRIPLAVLFGIFLYMGITSLSGIQ----------------LFDRILLLFKPPKYHPDVPFVKRVKTWRMHLFTGIQIICLAVLWVVKSTPASLALPFVLILTVPLRRLLLPLIFRELELQCLDGDDAKVTFDEAEGLDE--------------------------------YDEVPMPV---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P02730-1", "uniprot_id": "B3AT_HUMAN", "id": "P02730-1", "name": "Band 3 anion transport protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEELQD----------DYEDMMEENLEQEEYEDPDIPESQMEEPAAHDTEATATDYH----TTSHP------------GTHK------------------------------VYVELQELVMDEKNQELRWMEAA------------------------RWVQLEENLGEN-GAWGRPHLSHLTFWSLLELRRVFTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRPQDR--EELLRALLLKH--------------------------------SHAGELEALG--------------------------------------GVKPAVLTRSGD-------------------------------------------------------------------------------------------------------------------------------PSQPLLP-----QHSSLETQLFCEQGDGGTEGH-------------------SPSGILEKIPPDSEATLVLVGRADFLEQPVLGFVRLQEAAELEA-VELPVPIRFLFVLLGP--EAPHIDYTQLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTDAPSEQAL-LSLVPVQRELLRRRYQSS-------PAKPDSSFYKGLDLNGGPD-----------------------------DPLQQTGQLFGGLVRDIRRRYPYYLSDITDAFS------PQVLAAVIFIYFAALSPAITFGGLLGEKTRNQMGVSELLISTAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHPLQK-------TYNYNVLMVP-------------------------------------------------------KPQGPLPNTALLSLVLMAGTFFFAMMLRKFKNSSYFPG--------------------------------------KLRRVIGDFGVPISILIMVLVDFF---IQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASALPALLVFILIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKASTPGAA-AQIQEVKEQRISGLLVAVLVGLSILMEPI-LSRIPLAVLFGIFLYMGVTSLSGIQ----------------LFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPASLALPFVLILTVPLRRVLLPLIFRNVELQCLDADDAKATFDEEEGRDE--------------------------------YDEVAMPV---------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VT48-1", "uniprot_id": "Q9VT48_DROME", "id": "Q9VT48-1", "name": "Anion exchange protein", "aln": "-----------------------------MSFSSASGRENNVRKLSFLGFN--TKKKSGNEDPDEVLLDSEMDKVFAGNSARKDKFDVNTFQDNSQLPIG---------------SRKKNSIRTNDLNIEEDSEYESQTEPLNNAQNYDDIPEDFPLVSERAGHGD-------HSDNSVDEKHVQFGGKKKIPPSLSYDEQPTDQSHERKRRRSRHQYYRQ------------------------------------RKFSHQDSVEPKNKLEENGDAGARRISVQPEDTALEEADLNELRSHRSDDPRALRRHKIHHSSIKLRELPQIT----ISPFTNKKPEVDHSPHE-------------------IFVQLDELTGVGEDRE--WKETA------------------------RWIKYEEDVEEGSDRWGKPHVASLSFHSLLNLRRCLETGVVLLDLNEKDLPAVAYRVVEQMVIEDLIDINDK--PSVMRSLLLRHRHVNEHQGVLPFTKRKYNSYTSLQFLWMGADSAHQPYQQAQPPPRNLAKARRSICVTSSAPPTAAMLNVATATAAAAAIDHRRHSTMSYLGNLSGTDD--------------------------------------------------------------------------------------------------------------KKIKIMPAAEIGGSKRSN-----ELKIDMKDDMYSSSQEDLKKL-------------------QNDTILKRIPAGAEATTVLVGAVEFLEQPTIAFVRLSEGVLMPTLTEVPVPVRFMFVLLGP--RNFDLDYHEVGRSISTLMANEHFHSIAYKADDRKDLLSAINEFLDDSIVLPPGNWDRHDLLPFEELKAKKDWIRTRKIKALQVKRDSEMIKIGKDEEKALLEKQTLGAIGFTIGGGDGGGDGDSDDDNGRKKKKPSPLEKTGRLWGGLRNDLKRRMPMYKSDILDGLN------TETLAATIFMYFACLSTAITFGGLVSAKTNSWIGISETLISCSLVGIVFHCLSCQPLVIIGTTGPLLLFDEALMVFCTQHEFDFLSLRVYVGVWLIIIALTVSAFEGSVYVRLLTRFTQEIFSALITLIYIVETFMKLISIYRENPLLSDYNLPPPTLVAHEHATNESLLNA------------------------TASVTTNITQMVMNISTTAMPIGPPPLPKNQPNTALFCTILTLATFVVAYYLKLFRNSHFLGR--------------------------------------NARRALGDFGVPISIAIFVLVDYL---VPAVYTEKLVVPEGLSPSDPSKRGWYIG----FDTSSTWIPFACVIPALLVYILIFMESQISELIVDKPDRGLKKGSGLHWDIVLLCLLNCACGIFGMPWHCAATVRSVTHVSSVTIMSRTHAPGES-PRIVDVKEQRLSGFFVCLMIGLSVLMAPL-LRLIPMAVLFGVFLYMGVASMSGVQ----------------LFERIRLYFMPVKHYPPTSYVKRLRPWKLHLFTTIQVLCLVLLWSVKSSQFSLAFPFFLIMMVPIRQN-LTKLYKPEEMQALDGSEMKK--NDDDEPDF--------------------------------YEQTNIPA---------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8BTY2-1", "uniprot_id": "S4A7_MOUSE", "id": "Q8BTY2-1", "name": "Sodium bicarbonate cotransporter 3", "aln": "----------------------MEADGAGEQMRPLLT----------RGPDEEAVVDLGKTSSTVNTKFEKEELESHR--AVYVGVHVPFS-KESRRRHKHR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHKHHHRRR-KDKDSDKEDGRESPSYD-TPSQRVQFILGTEDDDEEHIPHD----------------------------------------LFTEMDELCYR-DGEEYEWKETA------------------------RWLKFEEDVEDGGDRWSKPYVATLSLHSLFELRSCILNGTVMLDMRASTLDEIADMVLDNMIASGQLDDSIR--ENVREALLKRH--------------------------------HHQNEKRFTSR-----------IPLVRSFADIG--------------------------------------------------------------------------------------------------------------------------------------------------ILASPQS-APGNLDNSKSGEMKGNGSGGSRENSTVDFSK---------------------VDMNFMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLSGLTEVPVPTRFLFLLLGP--AGKAPQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEPPKSVPSQEKRKIPVFPNGSAAMSVGPPKEDD-------------------------------------HHAGPELQRTGRLFGGLILDIKRKAPFFLSDFKDALS------LQCLASILFLYCACMSPVITFGGLLGEATEGRISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCRDYHLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFHLGEIYAFNMHNNLDELTSYTCVCAEPSNPSNE-----------TLELWKRKNITAYSVSWGNLTVSECKTFHGMFVGSACGPHGPYVPDVLFWCVVLFFTTFFLSSFLKQFKTKGYFPT--------------------------------------KVRSTISDFAVFLTIVIMVAIDYL---VG-IPSPKLHVPEKFEPTDPS-RGWIISPLGD---NPWWTLLIAAVPALLCTILIFMDQQITAVIINRKEHKLK--------------------------------------------------------------------------------------FIPMPVLYGVFLYMGVSSLKGIQ----------------FFDRIKLFGMPAKHQPDLIYLRYVPLWKVHVFTVVQLTCLVLLWVIK-ASAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPESKKKKEDDKK-----KKEKEEAERMLQD--------------DEDTVHLPFERGSLLQIPVKTLKYSIDPSVVNISDEMAKTAQWKALSMNTENAKVTRPNT----SPEKPVSVTINFEDEPSK-KYMDAETSL----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R1N3-1", "uniprot_id": "S4A7_RAT", "id": "Q9R1N3-1", "name": "Sodium bicarbonate cotransporter 3", "aln": "----------------------MEADGAGEQMRPLLT----------RGPDEEAVVDLGKTSSTVNTKFEKEELESHR--AVYVGVHVPFS-KESRRRHRHR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHKHHHRRR-KDKDSDKEDGRESPSYD-TPSQRVQFILGTEDDDEEHIPHD----------------------------------------LFTEMDELCYR-DGEEYEWKETA------------------------RWLKFEEDVEDGGDRWSKPYVATLSLHSLFELRSCILNGTVMLDMRASTLDEIADMVLDNMIASGQLDDSIR--ENVREALLKRH--------------------------------HHQNEKRFTSR-----------IPLVRSFADIGKKHSDPHLLERNGEGLSASRHSLRTGLSASNLSLRGESPLSLLLSHLLPSSRAGTPAGSRCTTPVPTPQNSPPSSPSLSRLTSRSSQQTQPQAPEVLVSPDRDDIPRVVIHPPEEDIEALK-GQEQKNEENTDFTP---------GILASPQS-APGNLDSSKSGEVKGNGSGGSRENSTVDFSK---------------------VDMNFMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLSGLTEVPVPTRFLFLLLGP--AGKAPQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEPPKSVPSQEKRKIPAFPNGSAPVSADPPKEAD-------------------------------------HHAGPELQRTGRLFGGLILDIKRKAPFFLSDFKDALS------LQCLASILFLYCACMSPVITFGGLLGEATEGRISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCRDYHLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFHLGEIYAFNMHNNLDALTSYTCVCAEPSNPSNE-----------TVELWERKNVTAASISWANLTVSECKTFHGMFVGSACGPHGPYVPDVLFWCVVLFFTTFFLSSFLKQFKTKRYFPT--------------------------------------KVRSTISDFAVFLTIVIMVAIDYL---VG-IPSPKLHVPEKFEPTDPS-RGWIISPLGD---NPWWTLLIAAVPALLCTILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSISHVNSLKVESECSAPGEQ-PKFLGIREQRVTGLMIFILMGLSVFMTSV-LKFIPMPVLYGVFLYMGVSSLKGIQ----------------FFDRIKLFGMPAKHQPDLIYLRYVPLWKVHVFTVVQLTCLVLLWVIK-ASAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPESKKKKEDDKK-----KKEKEEAERMLQG--------------DGDTVHLPFERGSLLQIPVKTLKY----------------------------------------SPEKPVSVTINFEDEPSK-KYMDAETSL----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6M7-1", "uniprot_id": "S4A7_HUMAN", "id": "Q9Y6M7-1", "name": "Sodium bicarbonate cotransporter 3", "aln": "----------------------MERFRLEKKLP---------------GPDEEAVVDLGKTSSTVNTKFEKEELESHR--AVYIGVHVPFS-KESRRRHRHR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHKHHHRRR-KDKESDKEDGRESPSYD-TPSQRVQFILGTEDDDEEHIPHD----------------------------------------LFTEMDELCYR-DGEEYEWKETA------------------------RWLKFEEDVEDGGDRWSKPYVATLSLHSLFELRSCILNGTVMLDMRASTLDEIADMVLDNMIASGQLDESIR--ENVREALLKRH--------------------------------HHQNEKRFTSR-----------IPLVRSFADIGKKHSDPHLLERNGEGLSASRHSLRTGLSASNLSLRGESPLSLLLGHLLPSSRAGTPAGSRCTTPVPTPQNSPPSSPSISRLTSRSSQESQRQAPELLVSPASDDIPTVVIHPPEEDLEAALKGEEQKNEENVDLTP---------GILASPQS-APGNLDNSKSGEIKGNGSGGSRENSTVDFSK---------------------VDMNFMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLTGLTEVPVPTRFLFLLLGP--AGKAPQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEPPKSVPSQEKRKIPVFHNGSTPTLGETPKEAA-------------------------------------HHAGPELQRTGRLFGGLILDIKRKAPFFLSDFKDALS------LQCLASILFLYCACMSPVITFGGLLGEATEGRISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLVFEKILYKFCRDYQLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFDLGETYAFNMHNNLDKLTSYSCVCTEPPNPSNE-----------TLAQWKKDNITAHNISWRNLTVSECKKLRGVFLGSACGHHGPYIPDVLFWCVILFFTTFFLSSFLKQFKTKRYFPT--------------------------------------KVRSTISDFAVFLTIVIMVTIDYL---VG-VPSPKLHVPEKFEPTHPE-RGWIISPLGD---NPWWTLLIAAIPALLCTILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVGVMLGVCSVMGLPWFVAATVLSISHVNSLKVESECSAPGEQ-PKFLGIREQRVTGLMIFILMGLSVFMTSV-LKFIPMPVLYGVFLYMGVSSLKGIQ----------------LFDRIKLFGMPAKHQPDLIYLRYVPLWKVHIFTVIQLTCLVLLWVIK-VSAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPESKKKKEDDKK-----KKEKEEAERMLQD--------------DDDTVHLPFEGGSLLQIPVKALKY----------------------------------------SPDKPVSVKISFEDEPRK-KYVDAETSL----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PN97-1", "uniprot_id": "A0A8M9PN97_DANRE", "id": "A0A8M9PN97-1", "name": "Anion exchange protein", "aln": "-----------------MQDFWGDVAHMRTTIGATAS----------SGNDDEAVVDQGKTSSNIHTNFEKEELESHR--AVYVGVHVPLG-RQSRRRHRHR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHKHHRKR--KDRCSEREDGRDSPTYD-TPSQRVQFILGTEDDDEEHIPHD----------------------------------------LFTELDELCFR-DGLTCEWKETA------------------------RWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVMLDMRANSIEEIADMVLDNMVASEQLDESVR--EKVRDAVLKRH--------------------------------HHQNEKKLSNR-----------IPLVRSFADIGKKHSDPHLLERNGEGLSTSRLSLLRRTSSTSTPPSSRRP-SRESRYSRSSIILNQLLSSANSTPSTTPQNSPPTAHRASP-SLRPPGPSQQGPELLVARGDRDDIPEVVVFPPEEDVGDPLPAFYAVQDEKVVHDPTRLLPLPQSGLLASPQS-APGILENSKSSESRINGTGGSRENSTVDFSRDSQSPFHCSCGSLGVGTKRPAVDMNFMKKIPPGAEASNVLVGEVDFLERPIIAFIRLSPAVLLTGLTEVPVPTRFLFLLLGP--FGKGAQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPTIRIEPPKSVPSQEKRKMPSMPNGSTPQS-DVIKQEA-------------------------------------HHAGPELQRTGRIFGGLVLDLKRKAPFYWSDVRDAFS------LQCLASILFLYCACMSPVITFGGLLGEATKNNISAIESLFGASLTGVAFSLFAGQPLTILGSTGPVLVFEKILFKFCSDYGLSYLPLRTSIGLWTAFLCLLLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFQLGKMYPFNMHDDLNNLTFYTCQCSPPSNTTQK-----------MEQSWNQSGFTYDTINWTELNVQDCRDLHGEFVGPACGHNGPYIPDVLFWSVILFFTTFFLSSFLKQFKTKRYFPT--------------------------------------KVRSSISDFAVFLTIMIMVLVDYL---VG-IPSPKLHVPDRFEPTSKN-RGWLISPLGD---NPTWTLFAAAIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLVVAVMLGVCSIMGLPWFVAATVLSISHVNSLKVESECSAPGEQ-PKFLGIREQRVTGLMIFVLMGLSVFMTSI-LKFIPMPVLYGVFLYMGVSSLRGIQ----------------FFDRIKLFGMPAKHQPDLIYLRYVPLWKVHIFTLVQLTCLVLLWVIK-VSAAAVVFPMMVLALVFVRKLLDFCFTKRELSWLDDLMPESKKKKEDDKK-----KKAKEEAQRMMEA---------------EEEIEIPFDGGDQLEIPEKTIQISTDPSVVNISDEMAKTAAWKG-GNSSESATLLKASA----SEEKTACIKIRVEDEDEEDKRVDTETSL----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8JZR6-1", "uniprot_id": "S4A8_MOUSE", "id": "Q8JZR6-1", "name": "Electroneutral sodium bicarbonate exchanger 1", "aln": "----------------------MP--AGSNEPDGVLS---------YQRPDEEAVVDQGGTSTILNIHYEKEELEGHR--TLYVGVRMPLG-RQSHRHHRTH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQKHRRRGGRGKGASQGEEGLEALAHD-TPSQRVQFILGTEED-EEHVPHE----------------------------------------LFTELDEICMK-EGEDAEWKETA------------------------RWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGSVLLDMRASSIEEISDLILDQQELLRDLSDSVR--VKVREALLKKH--------------------------------HHQNERRRNNL-----------IPIVRSFAEVGKKQSDPHSMDRD-------------------------------------------------------------------------------------------------------------------------------------GQTVSPQS--ATNLE---------VKNGVNCEHSPVDLSK---------------------VDLHFMKKIPTGAEASNVLVGEVDTLDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGP--VGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIEPEPHGG---------------------------------------HSGPELERTGRLFGGLVLDVKRKAPWYWSDYRDALS------LQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKDYALSYLSLRALIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCVLPENPNNH-----------TLQYWKDHNILAAEVNWANLTVSECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFATFIVSSTLKTFKTSRYFPT--------------------------------------RVRSMVSDFAVFLTIFTMVVLDFL---IG-VPSPKLQVPNVFKPTRDD-RGWFINPIGP---NPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQ-PKFLGIREQRVTGLMIFVLMGCSVFMTAV-LKFIPMPVLYGVFLYMGVSSLQGIQ----------------FFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLVQLTCLVLLWVIK-ASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAK-----KKE-EEE-AEKML--------------DIGGDKFPLESRKLLSSPGKSSSFRCDPSEINISDEMPKTTV------------------------WKALSINSGNTKEKSPFN------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6RVG2-2", "uniprot_id": "S4A8_RAT", "id": "Q6RVG2-2", "name": "Electroneutral sodium bicarbonate exchanger 1", "aln": "----------------------MP--AGSNEPDGVLS---------YQRPDEEAVVDQGGTSTILNIHYEKEELEGHR--TLYVGVRMPLG-RQSHRHHRTH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQKHRRRGGRGKGASQGEEGLEASAHD-TPSQRVQFILGTEED-EEHVPHE----------------------------------------LFTELDEICMK-EGEEAEWKETA------------------------RWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGSVLLDMRASSIEEISDLILDQQELLRDLSDSVR--VKVREALLKKH--------------------------------HHQNEKKRNNL-----------IPIVRSFAEVGKKQSDPHSMDRD-------------------------------------------------------------------------------------------------------------------------------------GQTVSPQSAPATNLE---------VKNGVNCEHSPVDLSK---------------------ADLHFMKKIPAGAEASNVLVGEVDTLDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGP--VGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNICHVEPEPHGG---------------------------------------HSGPELERTGRLFGGLVLDVKRKAPWYWSDYRDALS------LQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCALPENPNNH-----------TLQYWKEHSIPTADVNWANLTVSECQEMHGEFIGSACGHHGPYTPDVLFWSCILFFATFIVSSTLKTFKTSRYFPT--------------------------------------RVRSTVSDFAVFLTIFTMVILDFL---IG-VPSPKLQVPSVFKPTRDD-RGWFISPIGP---NPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLVVAIMLGVCSLMGLPWFVAATVLSITHVNSLKLESECSAPGEQ-PKFLGIREQRVTGLMIFVLMGCSVFMTAV-LKFIPMPVLYGVFLYMGVSSLQGIQ----------------FFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLVQLTCLVLLWVIK-ASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAK-----KKE-EEEEAEKML--------------DIGGDKFPLESRKLLSSPGKNNSFRCDPSEINISDEMPKTTV------------------------WKALSINSGNTKEKSPFN------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2Y0W8-1", "uniprot_id": "S4A8_HUMAN", "id": "Q2Y0W8-1", "name": "Electroneutral sodium bicarbonate exchanger 1", "aln": "----------------------MPA-AGSNEPDGVLS---------YQRPDEEAVVDQGGTSTILNIHYEKEELEGHR--TLYVGVRMPLG-RQSHRHHRTH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQKHRRRG-RGKGASQGEEGLEALAHD-TPSQRVQFILGTEED-EEHVPHE----------------------------------------LFTELDEICMK-EGEDAEWKETA------------------------RWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSDLNDSMR--VKVREALLKKH--------------------------------HHQNEKKRNNL-----------IPIVRSFAEVGKKQSDPHLMDKH-------------------------------------------------------------------------------------------------------------------------------------GQTVSPQSVPTTNLE---------VKNGVNCEHSPVDLSK---------------------VDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGP--VGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGG---------------------------------------HSGPELQRTGRLFGGLVLDIKRKAPWYWSDYRDALS------LQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCTLPENPNNH-----------TLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPT--------------------------------------RVRSMVSDFAVFLTIFTMVIIDFL---IG-VPSPKLQVPSVFKPTRDD-RGWIINPIGP---NPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQ-PKFLGIREQRVTGLMIFVLMGCSVFMTAI-LKFIPMPVLYGVFLYMGVSSLQGIQ----------------FFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIK-ASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAK-----KKAKEEEEAEKML--------------EIGGDKFPLESRKLLSSPGKNISCRCDPSEINISDEMPKTTV------------------------WKALSMNSGNAKEKSLFN------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5DTL9-1", "uniprot_id": "S4A10_MOUSE", "id": "Q5DTL9-1", "name": "Sodium-driven chloride bicarbonate exchanger", "aln": "----------------------MEIKDQGAQMEPLLP----------TRNDEEAVVDRGGTRSILKTHFEKEDLEGHR--TLFIGVHVPLGGRKSHRRHRHR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHKHRKRD--RERDSGLEDGRESPSFD-TPSQRVQFILGTEDDDEEHLPHD----------------------------------------LFTELDEICWR-EGEDAEWRETA------------------------RWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTIEEIADMVLDQQVSSGQLNEDVR--HRVHEALMKQH--------------------------------HHQNQKKLANR-----------IPIVRSFADIGKKQSEPNSMDKNAGQVVSPQSAPACAE-------------------------------------------NKNDVSRENSTVDFSKG---------------------------------------------------------LGGQQKGHT-SPCGMK---------QRLD--KGPPHQQERE---------------------VDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPSRFLFILLGP--LGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHGG---------------------------------------HSGPELQRTGRIFGGLILDIKRKAPFFWSDFRDAFS------LQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSETYPINMHNDLELLTQYSCNCMEPHSPSND-----------TLKEWRESNLSASDIIWGNLTVSECRSLHGEYVGRACGHGHPYVPDVLFWSVILFFSTVTMSATLKQFKTSRYFPT--------------------------------------KVRSIVSDFAVFLTILCMVLIDYA---IG-IPSPKLQVPSVFKPTRDD-RGWFVTPLGP---NPWWTIIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQ-PKFLGIREQRVTGLMIFILMGSSVFMTSI-LKFIPMPVLYGVFLYMGASSLKGIQ----------------LFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTVIQMSCLGLLWIIK-VSRAAIVFPMMVLALVFVRKLMDFLFTKRELSWLDDLMPESKKKKLEDAE-----KEE--EQSMLAME--------------DEGTVQLPLEG-----------HYRDDPSVINISDEMSKTAM------------------------WGNLLVTADNSKEKESRFPSKSSPS-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q80ZA5-1", "uniprot_id": "S4A10_RAT", "id": "Q80ZA5-1", "name": "Sodium-driven chloride bicarbonate exchanger", "aln": "----------------------MEIKDQGAQMEPLLP----------TRNDEEAVVDRGGTRSILKTHFEKEDLEGHR--TLFIGVHVPLGGRKSHRRHRHR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHKHRKRD--RERDSGLEDGGESPSFD-TPSQRVQFILGTEDDDEEHIPHD----------------------------------------LFTELDEICWR-EGEDAEWRETA------------------------RWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVR--HRVHEALMKQH--------------------------------HHQSQKKLTNR-----------IPIVRSFADIGKKQSEPNSMDKN-GQVVSPQSAPACAE-------------------------------------------NKNDVSRENSTVDFSKG---------------------------------------------------------LGGQQKGHT-SPCGMK---------QRLD--KGPPHQQERE---------------------VDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPSRFLFILLGP--LGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKTPSLPNGTAAHGGPEQHGG---------------------------------------HSGPELQRTGRIFGGLILDIKRKAPFFWSDFRDAFS------LQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSESYPINMHNDLELLTQYSCNCMEPHSPSND-----------TLKEWRESNISASDIIWGNLTVSECRSLHGEYVGRACGHGHPYVPDVLFWSVILFFSTVTMSATLKQFKTSRYFPT--------------------------------------KVRSIVSDFAVFLTILCMVLIDYA---IG-IPSPKLQVPSVFKPTRDD-RGWFVTPLGP---NPWWTIIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQ-PKFLGIREQRVTGLMIFILMGSSVFMTSI-LKFIPMPVLYGVFLYMGASSLKGIQ----------------LFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTVIQMSCLGLLWIIK-VSRAAIVFPMMVLALVFVRKLMDFLFTKRELSWLDDLMPESKKKKLEDAE-----KEE--EQSMLAME--------------DEGTVQLPLEG-----------HYRDDPSVINISDEMSKTAM------------------------WGNLLVTADNSKEKESRFPSKSSPS-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6U841-1", "uniprot_id": "S4A10_HUMAN", "id": "Q6U841-1", "name": "Sodium-driven chloride bicarbonate exchanger", "aln": "----------------------MEIKDQGAQMEPLLP----------TRNDEEAVVDRGGTRSILKTHFEKEDLEGHR--TLFIGVHVPLGGRKSHRRHRHR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHKHRKRD--RERDSGLEDGRESPSFD-TPSQRVQFILGTEDDDEEHIPHD----------------------------------------LFTELDEICWR-EGEDAEWRETA------------------------RWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVR--HRVHEALMKQH--------------------------------HHQNQKKLTNR-----------IPIVRSFADIGKKQSEPNSMDKNAGQVVSPQSAPACVE-------------------------------------------NKNDVSRENSTVDFSKG---------------------------------------------------------LGGQQKGHT-SPCGMK---------QRHE--KGPPHQQERE---------------------VDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGP--LGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHGG---------------------------------------HSGPELQRTGRIFGGLILDIKRKAPYFWSDFRDAFS------LQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHNPSNG-----------TLKEWRESNISASDIIWENLTVSECKSLHGEYVGRACGHDHPYVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPT--------------------------------------KVRSIVSDFAVFLTILCMVLIDYA---IG-IPSPKLQVPSVFKPTRDD-RGWFVTPLGP---NPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQ-PKFLGIREQRVTGLMIFILMGSSVFMTSI-LKFIPMPVLYGVFLYMGASSLKGIQ----------------FFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIK-VSRAAIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPESKKKKLEDAE-----KEE--EQSMLAME--------------DEGTVQLPLEG-----------HYRDDPSVINISDEMSKTAL------------------------WRNLLITADNSKDKESSFPSKSSPS-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GI31-1", "uniprot_id": "A0AC58GI31_DANRE", "id": "A0AC58GI31-1", "name": "Anion exchange protein", "aln": "----------------------MDAKDQSAQMEPLLPAVVTSPERQSVRNDDEAIVDRGGTRSMLKAGFEKEELEGHR--TLYIGVHVPLG-RRTRRRHRHH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHRHRKRS--RERDSGVEDGRESPSYN-TPSQRVQFLLGTEDDDEEHIPHD----------------------------------------LFTELDEICLR-EGEDAEWRETA------------------------RWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCIINGTVMLDMRAGSLEEIADMILDQQEVAGHLEDDVR--KKVKEALLKQH--------------------------------HHQNQKKLANR-----------IPIVRSFADIGKKQSESNCLDKNG-TSSHLFKSPVCG--------ADDIQGSCCS------PCCWSSVS----ITSPVHPPFSSSTLHQSQKNSFSQ--------------DRGSALD-------------------------------------AGQTISPQT-QPMNIE---------VKHDVSRENSTVDFSK---------------------IDLHFMKKIPPGAEASNVLVGELEFLDRPVVAFVRLSPAVLLNGLAEVPITTRFLFILLGP--LGKGAQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLIAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNG--ELAETEEHGG---------------------------------------HGGPELQRTGRLFGGLILDVKRKAPHLLSDFGDALS------LQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRVCIGLWTAFLCLLLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLGETYQFNKNNNLDKLTTYRCSCIEPENPSNA-----------TLQYWEQNNISAPEIFWEALEVEDCIEKKGVFVGSACGPHGPYVPDVLFWSIVLFFSTVAMSAFLKEFKTSRYFPT--------------------------------------KVRSIISDFAVFITIVTMVLVDYA---LG-VPSPKLQVPNEFKPTRDD-RGWLISPLGP---NPWWTCVITVIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLFMVGVMLGVCSIMGLPWFVAATVLSISHVNSLKLESECSAPGEQ-PKFLGIREQRVTGLMIFLLMGCSVFMTSV-LKFIPMPVLYGVFLYMGASSLRGIQ----------------FFDRLRLFGMPAKHQPDFIYLRHVPLRKVHLFTIIQLSCLVLLWVIK-TSRAAIVFPMMVLALVFIRKLLDFIFTKRELSWLDDLMPESKKKKLEDAE-----REE--EQSILAE---------------EEGIVQVPLEG-----------HYKDDPSTVNITDEMSKGSFGST---------------------WNTINSKNDPNTKSP------VP-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58GS41-1", "uniprot_id": "A0AC58GS41_DANRE", "id": "A0AC58GS41-1", "name": "Anion exchange protein", "aln": "----------------------MDVKDQGAQMEPLLPAVQS-PASDSERQDEEAVLDRGGTRSMLNTNFEKEELEGHR--TLYIGVHVPLG-RRSHRRHRHH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHRHRKRS--RERDSGTEDGRESPSYTDTPSQRVQFLLGMEDD-EEHIPHA----------------------------------------LFTELDEICLK-EGEDAEWKETA------------------------RWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVMLDMRASSLEEIADMVLDQHETSGPLGEEVR--KKIRNALLKQH--------------------------------HHQNQKKLANR-----------IPIVRSFADIGRKQSEPHSMDKNVTTTSHSSPSPCCSFWSRFSSSVRDRQVLLCPDWPLRCPKCVSSPQKLHPCPSATPAPNSSLIRHHKTHIPFSKRLSPPYGYHVIPTLNFEEESP-------------------------------------SGQMVSPQT-QPINTE---------GRGEGSRENSAVDFSK---------------------IDLHFMKKIPPGAEASNILVGELEFLEKPVVAFIRLSPAVLLNGLAEVPITTRFLFILLGP--MGKGPQYHEIGRSIATLMTDEVFHDVAYKAKERSDLVAGIDEFLDQVTVLPPGEWDPTIRIEPPKNVPSQEKRKVPPLANGGADLGEEEEHGG---------------------------------------HGGPELQRTGRIFGGLFLDIKRKAPHYLSDYTDALS------LQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRVCIGLWTAFFCLLLVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLIHLGETYPFNMHNDLNKLTQYSCVCTIPKEPSNA-----------TLKYWEEKNITASEIDWLGLDVKGCVENRGEFVGSACGHHGPYIPDVLFWSVVLFFSTVAMSSFLKEFKTSRYFPT--------------------------------------KVRQIISDFAVFITIMTMVLIDYG---LG-VPSPKLQVPNVFKPTRDD-RGWIISPLGP---NPWWTVIVTCIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLFVVGVMLGVCSVMGLPWFVAATVLSISHVNSLKLESECSAPGEQ-PKFLGIREQRFTGLMIFVLMGSSVFMTSV-LKHIPMPVLYGVFLYMGASSLRGIQ----------------FFDRLKLFGMPAKHQPDFIYLRHVPLRKVHMFTIIQLSCLVLLWVIK-TSRAAIVFPMMVLALVFIRKLLDFVFSKRDLSWLDDLMPESKKKKMEDAQ-----QEE--NQCVLIE---------------DEGIVQVPLEG-----------HYKDDPSTVNITDEMTKTSFGNV---------------------WKGLNPESANKEESSKRFGFNIPTEYVSLHMHDTSITTNLQMLH----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IPI3-1", "uniprot_id": "Q8IPI3_DROME", "id": "Q8IPI3-1", "name": "Anion exchange protein", "aln": "----------------------MAEKNEYIELPWTMN---------SSSGDDEAPKDPRTGGEDFTQQFTENDFEGHRAHTVYVGVHVPGGRRHSQRRRKHHHS----------------------------------------------------------------------------------------------------------------------------------------------------------GPGGG-----GGGGGGGGSIGGSGSVGGGAGKDNVSEKQQEVERPVTP--PAQRVQFILGEDVDDGTHVSHP----------------------------------------LFSEMGMLVK--EGDEIEWKETA------------------------RWIKFEEDVEEGGNRWSKPHVATLSLHSLFELRRLLVNGSVMLDMEAQNLEVMADLVCDHMVSAGTLPPGVK--DKVKDALLRRH--------------------------------RHQHEYAKKTR-----------LPIIRSLADMRNHSSSKKKKSNSKHSRPAQN----------------------------------------------------------------------------------------------------------------------------LSSITEDMVKSPSNQS--------MARPGSGTELSEQQHKG----------------------NTHFMRKIPPGAEASNILVGEVDFLERTLSCFIRLSQAVVLGDLTEVPVPTRFVFILLGP--PGSQSNFHEIGRAMATLMSDEIFHEVAYRARKRDHLLSGVDEFLDAVTVLPPGEWDPTIRIEPPAAIPSQEVRKRP--PELPKEEVDEEEEEAR-------------------------------------LREENGLSRTGRLFGGLINDIKRKAPWYISDYKDALS------MQCVASWIFLYFACLSPIITFGGLLAEATGKHMAAMESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEFCLKMGWDYMTFRFWIGMWVAGICIVLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVIGKNFPVNQG-------IYDCVCTPPIGSN------------------------ASVIDYAKYNWDSCESYNGTLVGGDCG--TPPTENVFLMSVVLCAGTFLISTVLKEFKNALFFPS--------------------------------------IVRQYISDFSVLIAIFAMSFFDYS---LG-VPTQKLEVPNELKPTLST-RGWLIPPFVEK--NPWWSAIIAVFPALLGTILIFMDQQITAVIVNRKENKLKKGCGYHLDLFILSILIAICSMMGLPWFVAATVLSINHVNSLKLESECSAPGEK-PQFLGVREQRVTHILIFLTIGVSVLLTPL-LGNIPMPVLFGVFLYMGVASLKGLQ----------------FFDRILIMFMPAKYQPDYMFLRQVPIKRVHLFTMIQLACLIILWLIKSFSQTSILFPLMLVVMIGIRKALDLVFTRRELKILDDIMPEMTKRAAADDL-----HKLDAEDNHHQHPPGSGAGANYNADKSGPTTIHIPLSGNKTGTKGPTVNIPQEAVNRTAVWQQINKDGNGISEQLIIPVTLKVRQINGNHAPSSATLSPRLSPMHEADEYSEAPTNSPAHPAGNQQQQQQQINNCKEAAKLDGSCSNNSQISPANITPV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E9Q3M5-1", "uniprot_id": "S4A5_MOUSE", "id": "E9Q3M5-1", "name": "Electrogenic sodium bicarbonate cotransporter 4", "aln": "---------------------------------------------------MKVDEEKAGVKKLDPTSYKRRQPEQ-DFPSIHIGFPVPSYSQRKSDSKGHLSG------------------------------------------------------------------------------------------------------------------------------------------------------------------LQKVQWSLKPGKPQQELAGP----GIRASSQGGAVDFTKRTRSPAAEQLQDILGEEDE-APNPT----------------------------------------LFTEMDTLQHD--GDQMEWKESA------------------------RWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSCSLPQIIDDVIEKQIEDGLLRPELR--ERVSYVLLRKH--------------------------------RHQTKK-----------------PIHRSLADIGKSVSTTNRSSARSSSA-------------------------------------------------------------------------------------------------------------------------GPTLHRSTEDLRIRQSTSYGHLCH--------AQSRSMNDISHTPNTDQ--------------------RKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLVQSAMLGGVTEVPVPTRFLFILLGP--SGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAEPGQMNGSVGGGGASAGGG-------GSGGGAGGSGAGGVGSGDEAEMPAMHEIGEELIWTGRFFGGLCLDVKRKLPWFPSDFYDGFH------LQSISAVLFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKANGLDYMEFRLWIGLHSAIQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINTDFKPDFITTYKCECVAPDTVNTT-TVNASAPLAPNTNTSLYTPLNLTALDWSLLSKKECLSYGGRLLGSSCQ----FVPDLALMSFILFFGTYSMTLTLKKFKFSRYFPT--------------------------------------KVRTLVADFSIVFSILLFCGIDAC---FG-LQTPKLHVPSVIKPTRPD-RGWFVAPFGK---NPWWVYPASILPALLVTILIFMDQQITAVIVNRKENKLRKAAGYHLDLFWVGILMALCSFTGLPWYVAATVISIAHIDSLKMETETSAPGEQ-PQFLGVREQRVTGVMVFILTGISVFLAPI-LKYIPMPVLYGVFLYMGVASLNGIQ----------------FWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLALLWILK-STMAAIIFPVMILGLIIVRRLLDLIFSQHDLAWIDNILPEKDKKETD--------KKKKRRKEVHETA--------------EKEVAMPQFLPPS----------------VVKIPMEGIPSDP-----------------------QNGIHCVARKRSSSWSYSL------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6RI88-1", "uniprot_id": "S4A5_RAT", "id": "Q6RI88-1", "name": "Electrogenic sodium bicarbonate cotransporter 4", "aln": "---------------------------------------------------MKV-EEKAGVKKLEPTSYRRRHPEQ-DFPSIHIGFPVPGYSQRKSDSKGHLSG------------------------------------------------------------------------------------------------------------------------------------------------------------------LQRVQWSLQPDKSQQDLAGPD---GIKASSLGGSVDFTKRIRSPAAEQLQDILGEEDE-APNPT----------------------------------------LFTEMDTLQHD--GDQMEWKESA------------------------RWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEGGLLRPELR--ERVSYVLLRKH--------------------------------RHQTKK-----------------PIHRSLADIGKSVSTTNRSSARSPSA-------------------------------------------------------------------------------------------------------------------------GPTLHHSTEDLRIRQSTSYGHLCH--------AQSRSMNDISHTPNTDQ--------------------RKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLAQSSMLGGVTEVPVPTRFLFILLGP--SGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAGVDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGRSGASAGGG-------GSGGGAGGSGAGGGGSGNEAEMPAMHEIGEELIWTGRFFGGLRLDVKRKLPWFPSDFYDGFH------IQSISAVLFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKANGLDYMEFRLWIGLHSAIQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINTDFKPDSITTYKCECVAPDTVNTT-TVNDSALLVPNTNMSVYTPLNLTALDWSLLSKKECLSYGGRLLGSSCQ----FVPDLALMSFILFFGTYSMTLTLKKFKFSRYFPT--------------------------------------KVRTLVADFSIVFSILLFCGIDAC---FG-LQTPKLHVPNVIKPTRPD-RGWFVAPFGK---NPWWVYPASILPALLVTILIFMDQQITAVIVNRKENKLRKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQ-PQFLGVREQRVTGVMVFILTGISVFLAPI-LKYIPMPVLYGVFLYMGVASLNGIQ----------------FWDRCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLALLWILK-STMAAIIFPVMILGLIIVRRLLDLIFSQHDLAWIDNILPEKEKKESD--------RKK-RRKEVHENT--------------DKE---PQFLPPS----------------VVKIPMEGIPSDP-----------------------QNGIHCVGRKRSSSWSHSL------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BY07-1", "uniprot_id": "S4A5_HUMAN", "id": "Q9BY07-1", "name": "Electrogenic sodium bicarbonate cotransporter 4", "aln": "---------------------------------------------------MKVKEEKAGVGKLDHTNHRRRFPDQKECPPIHIGLPVPTYPQRKTDQKGHLSG------------------------------------------------------------------------------------------------------------------------------------------------------------------LQKVHWGLRPDQPQQELTGP----GSGASSQDSSMDLISRTRSPAAEQLQDILGEEDE-APNPT----------------------------------------LFTEMDTLQHD--GDQMEWKESA------------------------RWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELR--ERVSYVLLRRH--------------------------------RHQTKK-----------------PIHRSLADIGKSVSTTNRSPARSPGA-------------------------------------------------------------------------------------------------------------------------GPSLHHSTEDLRMRQSANYGRLCH--------AQSRSMNDISLTPNTDQ--------------------RKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPTRFLFILLGP--SGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFH------IQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECVAPDTVNTT-VFNASAPLAPDTNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCK----FIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPT--------------------------------------KVRALVADFSIVFSILMFCGIDAC---FG-LETPKLHVPSVIKPTRPD-RGWFVAPFGK---NPWWVYPASILPALLVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQ-PQFLGVREQRVTGIIVFILTGISVFLAPI-LKCIPLPVLYGVFLYMGVASLNGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILK-STVAAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEKKETD--------KKRKRKKGAHEDC--------------DEE---PQFPPPS----------------VIKIPMESVQSDP-----------------------QNGIHCIARKRSSSWSYSL------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GNP0-1", "uniprot_id": "A0AC58GNP0_DANRE", "id": "A0AC58GNP0-1", "name": "Anion exchange protein", "aln": "-----------------------------------------------------MDHDWQGSRRSG----HRSKHNEDEEESVYIGVPVPRSYRRKRRHRKHAS---------------------------------------------------------------------------------------------------------------------------------------------------------------------RHSHDRDKHHSRHEHADPEENCDPEEAEQENELSDVNSTVSPAAERLRHILREDDE--PTPT----------------------------------------LFTEMDTLQHE--GGEMEWKESA------------------------RWVKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGCILLDLDGYSLPQIVDDMIEKQVQEGLIAPEIR--EKVSFVLLRKH--------------------------------RHQTKK-----------------PIHRSLADIGKP-SPSNRSPSPSPSAR-----------------------------------------------------------------------------------------------------------------------SGSGFHRSTEDLRARQSAGLGKLHP--------SQCRSMNDISVTPSSDQ--------------------LKNKFMKKIPRDAEASNVLIGEVDFLDKPFVAFVRLAQAATLGGLTEVPVPTRFLFVLLGP--SGKTKSYNEIGRAMATLMVDDLFSDVAYKARDREDLIAGIDEFLDEVIVLPPGEWDPKIRIEPPKKLPSAEMRKSVFSLNELGQPNGNAG---------------------------GGSASAEDEEMPAPHELGEELKFTGRFCGGLWLDIKRKAPWFFSDFYEGFH------IQSVSAVLFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTALAGAVFCMFGGQPLIILSSTGPILIFEKLLYEFSINNNIDYMEIRLWIGLHSCLQCLILVATDASYIIKYMTRFTEEGFSSLISFIFISDALKKMMSTFSYYPISPDFKPDLIISYRCDCQLPDQVSPL-NSTSPLAL---ENMSDYSMFNFSALDWTQISKKECLRLGGSLVGKSCK----YVPDLAMLSFILFFGTYSMTISLKKFKSSRYFPTKCRALIADFAIIISILVFCAVDYGMALDTPKLHVPTQIKLRKLISDFAIFTSIMTFVGLDMF---MG-LKTPKLIVPTEFKPTRPD-RGWIVMPMGR---NPWWMCLASFVPALLVTILIFMDQQITAVIVNRKENKLKKGCGYHLDLFWVGVLMAVCSFMGLPWYVAATVISIAHIDSLKMESESSAPGEQ-PQFLGVREQRLTGTLVFVLTGVSVFMAPI-LQFIPMPVLYGVFLYMGVASLHGIQ----------------FWERIKLYLMPAKHQPDFVFLRHVPLRRVHLFTLLQITCLAVLWILK-STVAAIVFPVMILGLMVVRKALDLIFSQHDLAWLDDILPDKDKKKKEDEKK-----KKKSKTDEHNNS--------------DEECVCAVDSSS-----------------SLKIPLELLNPSS--------------------------NPPPASHTPSEQNTHK------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58JP69-1", "uniprot_id": "A0AC58JP69_DANRE", "id": "A0AC58JP69-1", "name": "Anion exchange protein", "aln": "-----------------------------------------------------MDHDR-GMGNSR----YRYEEEED-HQSIYIGVPVPRGYRRKRRRRRSSMS----------------------------------------------------------------------------------------------------------------------------------------------------------SRDADVDRRLRHDHHRHEHYECDDRDRYDLEAGGLDQAEHNLPPDINRTMSPAAERLRYILGDDEETMPTPT----------------------------------------LFTEMDTLQHE--GDELEWRESA------------------------RWVKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLEGYSLPQIVDDIIDRQVEEGLIGPELR--DKISFVLLRKH--------------------------------RHQTKK-----------------PIHRSLADLGKSGSGGTRSPARTPAAQ-----------------------------------------------------------------------------------------------------------------------AAN-FNRSTEDLRTKQAANYGRLRH--------AQSRSMNDIADTPSTDQ--------------------LKNKFMKKIPRDAEASNVLVGEVDFLEKPFVAFVRLSQATTLGGLTEVPVPTRFLFVLLGP--PGKAKSYNEIGRAIATLMVDDLFSDVAYKARDREDLIAGIDEFLDEVIVLPPGEWDPKIRIEPPKKTPSADKRKSVFSLNELGQMNGTAG---------------------------GGGPIEEDEEMPVPHELGEELAYTGRFCGGLFLDMKRKLPWYPSDFYEGFH------IQSISAVLFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTALAGTVFCVFGGQPLIILSSTGPILIFEKLLYEFSKNNAIDYMELRLWIGIHSCIQCFILVATDASYIIKYMTRFTEEGFSSLISFIFISDAIKKMVGSFKYYPINTDFKPDYVTAYKCECVAPDPMATM-IFDVVVPVP--DNTSALFGFNITALDWTQLSKKECVKYGGSLVGQSCK----YVPDLALMSFILFCGTYTMTVTLKKFKFSRYFPT--------------------------------------KLRKLISDFSIFMSIMTFVGLDML---IG-LKTPKLIVPTEFKPTRPD-RGWFVMPFGK---NPWWVYLASFVPALLVTILIFMDQQISAVIVNRKENKLKKGCGYHLDLLWVGVLMAACSFMGLPWYVAATVISIAHIDSLKMESESSAPGEQ-PQFLGVREQRLTGILVFVLTGVSIFLAPI-LQFIPMPVLYGVFLYMGVASLSGIQ----------------FWDRIKLIMMPAKHQPDFSYLRHVPLRRVHLFTLVQIVCLAVLWILK-STFLAIIFPVMILGLMVVRKMLDMVFSQHDLAWLDDILPEKEKKKKDDEKKNIKKDKKKGKGGDDSED--------------DDKYHPYTNCTPGDS----------DLDRSITLHLKISCPSSPAM------------------PLARGMPCPVPQVKIEMESDYEDTDINPRGRHRDHRDMSSETTL-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O88343-1", "uniprot_id": "S4A4_MOUSE", "id": "O88343-1", "name": "Electrogenic sodium bicarbonate cotransporter 1", "aln": "-----------------------------------------------------MEDEAVLDRGASFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRRHKRKAG----------------------------------------------------------------------------------------------------------------------------------------------------------------------HKEKKEKERISENYSDK----SDVENADESSSSILKPLISPAAERIRFILGEEDDSPAPPQ----------------------------------------LFTELDELLAV-DGQEMEWKETA------------------------RWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIADHQIETGLLKPDLK--DKVTYTLLRKH--------------------------------RHQTKK-----------------SNLRSLADIGKTVSSASRMFSNPDNG-----------------------------------------------------------------------------------------------------------------------------------------SPAMTHRN--------LTSSSLNDISDKPEKDQ--------------------LKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGP--KGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPTIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHD-------------------------GGHGGGG-------HGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDALN------IQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDHNFDYLEFRLWIGLWSAFMCLVLVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSDFKVGYNTHFSCACLPPDPVNLSVSNDTTLAPEDLPTISSTDMYHNVTFDWAYLSKKECVKYGGKLVGNNCD----FVPDITLMSFILFLGTYTSSMAMKKFKTSRYFPT--------------------------------------TARKLISDFAIILSILIFCVIDAL---VG-VDTPKLIVPSEFKPTSPN-RGWFVPPFGG---NPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVVCSFMALPWYVAATVISIAHIDSLKMETETSAPGEQ-PKFLGVREQRVTGTLVFILTGLSVFMAPI-LKFIPMPVLYGVFLYMGVASLNGVQ----------------FMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILK-STVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDE------KKKKKKK-GSLDS--------------DNDDSDCPYSEKVPS----------IKIPMDIMEQQPFLSDNK-------------------------------PLDRERSSTFLERHTSC-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JI66-1", "uniprot_id": "S4A4_RAT", "id": "Q9JI66-1", "name": "Electrogenic sodium bicarbonate cotransporter 1", "aln": "-----------------------------------------------------MEDEAVLDRGASFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRRHKRKAG----------------------------------------------------------------------------------------------------------------------------------------------------------------------HKEKKEKERISENYSDK----SDVENADESSSSILKPLISPAAERIRFILGEEDDSPAPPQ----------------------------------------LFTELDELLAV-DGQEMEWKETA------------------------RWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIADHQIETGLLKPDLK--DKVTYTLLRKH--------------------------------RHQTKK-----------------SNLRSLADIGKTVSSASRMFSNPDNG-----------------------------------------------------------------------------------------------------------------------------------------SPAMTHRN--------LTSSSLNDISDKPEKDQ--------------------LKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGP--KGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHD-------------------------GGHGGGG-------HGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDALN------IQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDHSFDYLEFRLWIGLWSAFMCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSDFRVGYNTHFSCACLPPDPVNLSVSNDTTLAPEDLPTVSSTDMYHNATFDWAYLSKKECVKFGGKLVGNNCD----FVPDITLMSFILFLGTYTSSMAMKKFKTSRYFPT--------------------------------------TARKLISDFAIILSILIFCVIDAL---VG-VDTPKLIVPSEFKPTSPH-RGWFVPPFGG---NPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVVCSFMALPWYVAATVISIAHIDSLKMETETSAPGEQ-PKFLGVREQRVTGTLVFILTGLSVFMAPI-LKFIPMPVLYGVFLYMGVASLNGVQ----------------FMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTSLQVLCLALLWILK-STVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDE------KKKKKKK-GSLDS--------------DNDDSDCPYSEKVPS----------IKIPMDITEQQPFLSDNK-------------------------------PLDRERSSTFLERHTSC-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6R1-1", "uniprot_id": "S4A4_HUMAN", "id": "Q9Y6R1-1", "name": "Electrogenic sodium bicarbonate cotransporter 1", "aln": "-----------------------------------------------------MEDEAVLDRGASFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRRHKRKTG----------------------------------------------------------------------------------------------------------------------------------------------------------------------HKEKKEKERISENYSDK----SDIENADESSSSILKPLISPAAERIRFILGEEDDSPAPPQ----------------------------------------LFTELDELLAV-DGQEMEWKETA------------------------RWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELK--DKVTYTLLRKH--------------------------------RHQTKK-----------------SNLRSLADIGKTVSSASRMFTNPDNG-----------------------------------------------------------------------------------------------------------------------------------------SPAMTHRN--------LTSSSLNDISDKPEKDQ--------------------LKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGP--KGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHD-------------------------GGHGGGG-------HGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDALN------IQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCN----FVPDITLMSFILFLGTYTSSMALKKFKTSPYFPT--------------------------------------TARKLISDFAIILSILIFCVIDAL---VG-VDTPKLIVPSEFKPTSPN-RGWFVPPFGE---NPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQ-PKFLGVREQRVTGTLVFILTGLSVFMAPI-LKFIPMPVLYGVFLYMGVASLNGVQ----------------FMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILK-STVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDE------KKKKKKK-GSLDS--------------DNDDSDCPYSEKVPS----------IKIPMDIMEQQPFLSDSK-------------------------------PSDRERSPTFLERHTSC-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JKC2-1", "uniprot_id": "A0AC58JKC2_DANRE", "id": "A0AC58JKC2-1", "name": "Anion exchange protein", "aln": "---------------MASSSRNTLQVNEPRRYGSTLSLEEKCEQSFFLFYYYRVEDEAVLDRGASLLKPLCDQEEVEGHHTIYIGVHVPKSYRRRRRHRRRTS----------------------------------------------------------------------------------------------------------------------------------------------------------------------HKDRKE--KVSENTSDR----SDAENNEEASNSILKPLISPAAERIRFILGEDDDSPAPPQ----------------------------------------LFTELDELLSV-DGQEMEWKETA------------------------RWIKFEEKVEKGGERWSKPHVATLSLHSLFELRTCIEKGTIMLDLEASTLPGVVEMITDSQIESGLLKADLK--EKVMYTLLRKH--------------------------------RHQTKK-----------------SNLRSLADIGKTVSSASRLFSTPDNGNTARNPLESSVPCLTTR------------------------------------------------------------------------------------------------------TSEEVLRAPGSPSMGWPSSPTTAHRN--------LTSSSLNDISDKPEKDQ--------------------LKNKFMKKLPRDAEASNVLVGEVDFLDSPFVAFVRLQQAVMLGALTEVPVPTRFLFILLGP--KGKAKSYHEIGRAIATLMSDEVFHEIAYKAKDRQDLLAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYAGGDSTQMNGDTPHS-------------------------GGHGGGG-------HAVGDELKKTGKFCGGLILDVKRKVPFFFSDFYDSLH------IQSLSAILFIYLGTVTNAITFGGLLGDATENMQGVLESFLGTAVTGAVFCLLAGQPLIILSSTGPVLVFERLLFNFSRENDFDYLEFRLWIGLWSAFFCLVLVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMLKLAHYYPINSDFKIDYVTQYDCMCMAPTDANSSDVYTDPLDSTFVWTVNYTTDPR-MNATWSSLSKKECLKYGGELVGKACE----FVPDITLMSFILFFGTYTCSMCLKKFKTSPFFPT--------------------------------------TVRKLISDFAIILAILIFCGVDAL---VG-VETPKLIVPSEFKPTSPN-RGWFVPPFGG---NPWWVYLAASVPALLVTILLFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAVLLAVCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQ-PKFLGVREQRVTGVMVFILTGISVFMSPV-LKFIPMPVLYGVFLYMGVASLNGVQ----------------FMDRLKLLLMPAKHQPDLIYLRHVPLRKVHLFTFVQLLCLALLWVLK-STVAAIIFPVMILALVAVRKALDYIFSQHDLSFLDDVIPEKDKKKKEDE------KKKKKKKQGSIDS--------------DMEDEKSPLQSWTDI----------HRAEKRHYFQSSPMSSSERL------------------PLN--VPQIKIEMDPDDNNGFFWRSRGSETSI-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AL80-1", "uniprot_id": "A0A8M3AL80_DANRE", "id": "A0A8M3AL80-1", "name": "Anion exchange protein", "aln": "-------------------------------------MSDKN----------KMEDEAVVDRGASYIKNVCD-EEVEGHHTVYIGVNVPKSYRRRRRHRRRSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------HRERRE--RVTENVSDK----SDTENADDSSSSILKPLISPAAERIRFILGEDDSGPPPPQ----------------------------------------LFTELDELLAV-DGQELEWKETA------------------------RWIKFEEKVEKGGERWSKPHVATLSLHSLFQLKNCIEKGTIVLDMDANSLQQIVENITDSQIESGQLKADLR--ETVIYTLLRKH--------------------------------RHQTKK-----------------SNLRSLADIGKSVSSASRLFSSQEN---ARGPIDHTVPCFTTF------------------------------------------------------------------------------------------------------EPEEQMQMQRSNSMGLLCSPTTAHRN--------LTSTSLNDLSDKPEKDQ--------------------LNNKFMKKIPRDAEASNVLVGEVDFLDAPFVSFVRLQQSVMLGGLTEVPVPTRFLFILLGP--KGKAKSYREIGRAIATLMSDEVFHDIAYKARDRSDLLAGIDEFLDEVIVLPPGEWDPDIRIEPPKSVPSADKRKNNLAGGEGSQMNGGTPHD-------------------------GGSGGGGG------HAVGDELKMTGKFCGGLVLDIKRKLPFFASDFYDALN------IQSLSAILFIYLGTVTNAITFGGLLGDATENMQGVLESFVGTALTGAVFCLLAGQPLTILSSTGPVLVFERLLFNFSRENAFDYLEFRLWIGLWSGFMCLVLVATDASFLVQYFTRFTEEGFSALISFIFIYDAFKKMLKLAHHNPINSGYDLELVTQYGCHCTPP-EGNVSALYLEKMEA----LMNNTGQHH-LNATWASLSRSECQEWGGQLVGATCD----FVPDITLMSFILFFGTYACSMGLKKFKTSRFFPT--------------------------------------TVRKLISDFAIILAILIFCGVDAL---VG-VDTPKLIVPSEFKPTSPH-RGWFVAPFGG---NPWWVYLASFLPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVSILLVVCSFLGLPWYVAATVISIAHIDSLKMETETSAPGEQ-PKFLGVREQRVTGIMVFILTGLSVFMAPV-LKFIPMPVLYGVFLYMGVASLNGVQ----------------FLDRLELLLMPAKHQPDLIYLRHVPLRRVHLFTFIQVLCLALLWILK-STVAAIIFPVMILALVAVRKAMDYVFSQHDLSYLDDVMPEKDKKKKEDE------KKKKKKK-GSIDS--------------DMNDEISPCPSS-------------LPTDAKHFFPSRTVSSQDLN------------------PFKKMVPQIRIDLDPD-NNKFFWKTPSSETSL-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A494BA31-1", "uniprot_id": "B3A4_MOUSE", "id": "A0A494BA31-1", "name": "Anion exchange protein 4", "aln": "-----------------------------------------------------------------------------------MKLPGQGDFESSDAHENAHS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EEPDSGLGPGPG--LNGPSGIDIGESQVSKDPL----------------------------------------LFIQLNELLGW--PQALEWRETG------------------------RWLLFEEKLDMGAGRWSAPHVPTLELPSLQKLRSLLAEGIVLLDCQAQSLLELVEQVVSGES----LSPELR--GQLQALLLQRP--------------------------------QHHIQT-----------------MGIR------------------------------------------------------------------------------------------------------------------------------------------------------------------PCRES--------NAFRKASRDEDAPLKH----------------------QNPLRQKLPAGAEAAAVLAGELGFLEQPLGAFVRLRNPIVLEPLTEMILPSRFFCLLLGP--PTLGRSYHEMGRAAAVLLSDPQFQWSVRRASHLPDLLAALDAFLQEVTALPPGRWDRTARIPPPKYLPSQHKRFP-SKLQEVTSLSRQS------------------------------AALAEDKHHHGPHTPIPELQRTGRLFGGLIQDVRRKACWYTSDFLDALH------PQCFSAVFYIYLATVTNAITFGGLLGDATEGAQGVLESFLGTAVAGAAFCLMAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVTAFCLALVATEASLLVRYFTRFTEEGFCALISLIFIYDAMGKMLNLIRAYPIQ---RPG-SSAYGCFCQYPGTGGNTSEWTSAKLK----DTEDILSV-PGLVNASFLPPPECIRQGGHPLGPSCH----TVPDIAFFSLLLFFTSFLCAIALKHIKNSRFFPS--------------------------------------VVRKVLGDFSSVLAILLGCGLDTF---LG-LATPKLLVPTEFKPTLSG-RGWLVSPFGA---NPWWLSVAAALPALLLSILIFMDQQITAVILNRAEYRLQKGAGFHLDLFCVAVLMLFTSALGLPWYVSATVISLAHIDSLRRESKACIPGEA-PNFLGIREQRLTGLVVFVLTGVSIFLAPV-LKFIPMPVLYGIFLYMGVAALSSIQ----------------FVKRVQLLLMPRKHQPDMLLLRHVPLSRVHLFTAIQLACLGLLWVVK-STPAAIVFPLMLLGLVAIRKALEWVFSPQELLWLDELMPEEEETIPE---------NRSEPEHLFSGN--------------DSEDSELMYQPKAP---------------EINISVN------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K4V2-1", "uniprot_id": "B3A4_RAT", "id": "Q8K4V2-1", "name": "Anion exchange protein 4", "aln": "-----------------------------------------------------------------------------------MKLPGQEDFEGSDAHENVCS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EQLDGDLGPGSG--LDGPSDIDNGKAQGCKDPL----------------------------------------LFIQLNELLGW--PQALEWRETG------------------------RWLLFEEKLDIGAGRWSAPHVPTLALPSLQKLRGLLAEGIVLLDCPARSLLELVEQVVRVES----LSPELR--GQLQALLLQRP--------------------------------QHHIQT-----------------TGIR------------------------------------------------------------------------------------------------------------------------------------------------------------------PCRRS--------NAFRKASRDEDTLLKH----------------------QNPLRQKLPPGAEAAAVLAGELGFLEQPLAAFVRLQNPVVLEPLTEVVLPSRFFCLLLGP--STLGRSYHETGRAAAVLLSDPQFQWSVRRASNLHDLLAALDAFLQEVTALPPGRWDRTARIPPPKCLPSQHKRFP-SKLQEVTSLSRQS------------------------------AALAENKHHHGPHTPIPELQRTGRLFGGLVQDVRRKACWYPSDFLDALH------PQCFSAVLYIYLATVTNAITFGGLLGDATEGAQGVLESFLGTAVAGATFCLMAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVATFCLALVATEASLLVRYFTRFTEEGFCALISLIFIYDAVGKMLNLIRAYPIQ---RPG-SPAYSCFCQYPGTGGNASEFDSTMFK----DTEDVLNVHPGLVNASFLPPSECIRQGGYPRGPSCH----TVPDIAFFSLLLFFTSFLCAIALKHVKNSRLFPS--------------------------------------VVRKVFSDFSSVLAILLGCGLDAF---LG-LATPKLLVPTEFKPTLPG-RGWLVSPFGA---NPWWLSVAAALPALLLSILIFMDQQITAVILNRAEYRLQKGAGFHLDLFCVAVLMLFTSALGLPWYVSATVISLAHMDSLRRESKACVPGED-PNFLGIREQRLTGLVVFILTGVSIFLAPV-LKFIPMPVLYGIFLYMGVAALSSMQ----------------FMKRVQLLLMPRKHQPDVLLLRHVPLIRVHLFTAIQLACLGLLWVIK-STPAAIVFPLMLLGLVAVRKALEWIFSPQELLWLDELMPEEEKTIPE---------NRPEPEHLFSGN--------------DSENSELMYQPKAP---------------EINISVN------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96Q91-1", "uniprot_id": "B3A4_HUMAN", "id": "Q96Q91-1", "name": "Anion exchange protein 4", "aln": "---------------------------------------------------------------------------------MEMKLPGQEGFEASSAPRNIPS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GELDSNPDPGTGPSPDGPSDTESKELGVPKDPL----------------------------------------LFIQLNELLGW--PQALEWRETGSSSASLLLDMGEMPSITLSTHLHHRWVLFEEKLEVAAGRWSAPHVPTLALPSLQKLRSLLAEGLVLLDCPAQSLLELVEQVTRVES----LSPELR--GQLQALLLQRP--------------------------------QHYNQT-----------------TGTR------------------------------------------------------------------------------------------------------------------------------------------------------------------PCWGS--------THPRKASDNEEAPLREQ--------------------CQNPLRQKLPPGAEAGTVLAGELGFLAQPLGAFVRLRNPVVLGSLTEVSLPSRFFCLLLGP--CMLGKGYHEMGRAAAVLLSDPQFQWSVRRASNLHDLLAALDAFLEEVTVLPPGRWDPTARIPPPKCLPSQHKRLP-SQQREIRGPAVPR------------------------------LTSAEDRHRHGPHAHSPELQRTGRLFGGLIQDVRRKVPWYPSDFLDALH------LQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLESFLGTAVAGAAFCLMAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVATFCLVLVATEASVLVRYFTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQ---KPG-SSAYGCLCQYPGPGGNESQWIRTRPK----DRDDIVSMDLGLINASLLPPPECTRQGGHPRGPGCH----TVPDIAFFSLLLFLTSFFFAMALKCVKTSRFFPS--------------------------------------VVRKGLSDFSSVLAILLGCGLDAF---LG-LATPKLMVPREFKPTLPG-RGWLVSPFGA---NPWWWSVAAALPALLLSILIFMDQQITAVILNRMEYRLQKGAGFHLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESRACAPGER-PNFLGIREQRLTGLVVFILTGASIFLAPV-LKFIPMPVLYGIFLYMGVAALSSIQ----------------FTNRVKLLLMPAKHQPDLLLLRHVPLTRVHLFTAIQLACLGLLWIIK-STPAAIIFPLMLLGLVGVRKALERVFSPQELLWLDELMPEEERSIPE---------KGLEPEHSFSGS--------------DSEDSELMYQPKAP---------------EINISVN------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2AJN7-1", "uniprot_id": "S4A11_MOUSE", "id": "A2AJN7-1", "name": "Solute carrier family 4 member 11", "aln": "------------------------------------------------------------------MSQNE-----------HCQDSGEYFSAGTQGYFKN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NMEDNLEVREDSLGDEVFDTVNSSIVSGESIRFFVNVNLEVQPSKSDL---------------------------------------------------------EAATGG------------------------------CVLLHTSRKYLKLKNFEEEVRAHRDLDGFLAQASIILNETATSLDDVLRTMLNRFALDPNHAEPDCDLDLLMAKLFT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DAGAP-----------------MESKVHLLS---------------------DTIQGVTATVRGVQYEQSWLCIICTMKTLQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDITFRQKLLKTRTEEEFKEALVHQRQLLTMM-----MPRAAGHSMSSLHTHRHPQ------------------------------------------------------------PPKCKDFFPFGKGIWMDIMRRFPVYPMDFTDGIIGKSKSVGKYVTTTLFLYFACLLPTIAFGSLNDENTNGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLAIYTQVIRVICDDYNLDFNAFYAWTGLWNSFFLALYAFLNLSLLMNLFKRSTEEIIALFISITFVLDAVKGMVKIFGKYYYGH---HYHTKRTSSLVSLLGIGRSP------------------------NSSLHTALNASLLASPVEMATTSSPGSTHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHP--------------------------------------CVRETLSDCALPIAVLSFSLIG---------SYGFQEIEMSKFRYNPSESLFEVAQIHS---LSFKAIGSAMGLGFLLSLLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGHIYETIVDVKETRLTALGASVLVGLSLLLLPFPLQWIPKPVLYGLFLYIALTSLDGNQ----------------LFSRVALLLKEQTSYPPTHYIRRVPQRKIHYFTGLQILQLLLLCAFGMSSLPYMKMVFPLIMIAMIPIRYNLLPRIIEAKYLDVMDAEHRP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZVP9-1", "uniprot_id": "D3ZVP9_RAT", "id": "D3ZVP9-1", "name": "Solute carrier family 4 member 11", "aln": "------------------------------------------------------------------MSQNE-----------HCQDSGEYFSAATLGYFKN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DTDDNPDVREDSLGDEVFDTVNSSIVSGESIRFFVNVNLEVQPSKSDI---------------------------------------------------------EAATGG------------------------------CVLLHTSRKYLKLKNFEEEVRAHRDLDGFLAQASIILNETATSLDDVLRTMLNRFAQDPNHAEPDCDLDLLMAKLFT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DAGGP-----------------MESKVHLLS---------------------DTIQGVTATVRGLQYEQSWLCIVCTMKSLQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDITFRQKLLKTRTEEEFKEALVHQRQLLTMM-----MPRAAGHSMSSLHTHRHPR------------------------------------------------------------PPKCKDFFPFGKGIWVDIMRRFPVYPLDFTDGIIGKGKTVGKYVTTTLFLYFACLLPTIAFGSLNDENTNGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLAIYTQVIRVICDDYNLDFNAFYAWTGLWNSFFLALYAFLNLSLLMNLFKRSTEEIIALFISITFVLDAVKGMVKIFWKYYYGH---HYHTKRTSSLASLLGISRSP------------------------NTSLHTALNTSFLASPIEMTTASSPISTHSNQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHP--------------------------------------CVRETLSDCALPIAVLSFSLIS---------SYGFQEIEMSKFRYNPSESLFEVAQIHS---LSFKAISSAMGLGFLLSLLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGHIYETIVNVKETRLTALGASVLVGLSLLLLPFPLQWIPKPVLYGLFLYIALTSLDGNQ----------------LFSRVALLLKEQTSYPPTHYIRRVPQRKIHYFTGLQILQLLLLCAFGMSSLPYMKMVFPLIMIAMIPIRYNLLPRIIEAKYLDVMDAEHRP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NBS3-3", "uniprot_id": "S4A11_HUMAN", "id": "Q8NBS3-3", "name": "Solute carrier family 4 member 11", "aln": "------------------------------------------------------------------MAAATR-------RVFHLQPCENSPTMSQNGYFEDSSY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YKCDTDDTFEAREEILGDEAFDTANSSIVSGESIRFFVNVNLEMQATNTEN---------------------------------------------------------EATSGG------------------------------CVLLHTSRKYLKLKNFKEEIRAHRDLDGFLAQASIVLNETATSLDNVLRTMLRRFARDPDNNEPNCNLDLLMAMLFT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DAGAP-----------------MRGKVHLLS---------------------DTIQGVTATVTGVRYQQSWLCIICTMKALQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVHQRQLLTMVSHGPVAPRTKERSTVSLPAHRHPE------------------------------------------------------------PPKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASL------------------------NASLHTALNASFLASPTELPSA-----THSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHP--------------------------------------CVREILSDCALPIAVLAFSLIS---------SHGFREIEMSKFRYNPSESPFAMAQIQS---LSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQ----------------LVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILLPRIIEAKYLDVMDAEHRP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T691-1", "uniprot_id": "A0AB32T691_DANRE", "id": "A0AB32T691-1", "name": "", "aln": "------------------------------------------------------------------MKTDKDGKDMRGVTVNRFAEEAPSSGMAKNGYFYQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EMEQREREEHEEGSEEREEGQDSPIPSGDDIHLYG-----SQTHQGGP---------------------------------------------------------ETDVHG------------------------------CVLLNTSRRYVKLMNFEEEVRAHRDLDGFLERASILLHEDEASLDDVLKTMLRHVSQDPHTAEPGCNFEEIMSSLFT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DAGSQEV-------NDRSANFIFYDNVHLLS---------------------ETLQCVTATATGIQYQQSWLCILCNVKNLQRRHVCISRLDRPQNWGENCAEVRYVILILAPSKMKSTKTAMELGRTFASMFSDISFRQKLLESKTQEEFKEALVIQRYHLTAAKRKTTAVEGEETDPHSQKPLKSAESVFSHLVSLSLL----------------------------------------------CRGPCCRDFFRVGRGIYEDLCRRLPLYPSDFTDGLVGNNKALVKFMTTSIFLYIAVLLPAIAFGSLNDESTRGEIDVQKTIIGQSIGGIIYSLCAGSPLVIPLTTAPIAIFISVIRGICDDYELDFAAFYACIGLWNSLFLIMGGVFNLSLLVKLFKRSIEEVIALFISIAFVADAVKGTVKIFHDNYHAP------TLANGSAAELNRISG----------------------------SVHLGELNQTEAGPVSLPES----FILCTRARPLLCLLLMMGTLWVGYTLYQFRRSPFLHV--------------------------------------KMREILSDCALPISVLVFSYVG---------SYVFNDIALPVFNFHEG-PVFQVAPLDK---LTGASVLSAMGLGFLLFLLIFIDQNIVVSLTNAPENRLLKGTAYHWDLTLSGLINILMSVLGLPWMHAAFPHSTLHVRQLAIVEERVEGGHLYETIVSVKETRVTSLVANILIGVSVFLLPVPLQWIPKPVLYGLFLYIALTSIEGNQ----------------MCDRMALLLKEQTSYPPTHYIRKVPQRKIHYFTFLQMVQLLFLCAFGMYPLPYMKMIFPLLMFILIPIRNCLLPRIIEAKYLDIMDAQRM----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53838-1", "uniprot_id": "BOR1_YEAST", "id": "P53838-1", "name": "Boron transporter 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNESTRVTVSRGCTASDECAQALERTNDELDRESSVSESRSDEESHEKLSRR-------------------------------------------------------------------------RFPTLGIGIWLDLKDRIPYYKSDWVDAFN------YRVIPSIVDTYFNNLLPAIAFAQDMFDRTDNSYGVNEVLLSSAMAGIVFGVLGGQPLCIVGVTGPISIFNYTVYEIIKPLNTSYFGFMFWICMWSMIFHLVLAFTNAVCLLQYVTTFPCDIFGLFINVVYIQKGIQILTRQFSAKSGEK-----------------------------------------------------------------------------SVQDGFASVVVALVMTAFGLFFKLFHYYPLFSH--------------------------------------RIRTFISDYSTALSVLFWSSFTHFGGYLHDVKFKKLPITKAFFPTSKVNRPQNTWLAYEP--IPVKDVFIALPFGIFLTILFYFDHNVSSLMAQRHQYKLKKPSSFHYDFALLGLTTCISGVLGIPAPNGLIPQAPLHTETLLVRDSNQKVISC------VEQRFTNTFQGLMILGTMTRPLLVCLGEIPQAVLSGLFFIMGINGLMTNS----------------IIQRLVFLFSDPNRRDNTSPLMKVSKKSMLIFLSFSLTGFAGEFAIT-NTIAAIGFPLVLLLSVLVSFSFAYIFPTEELKILDTNVAQKFTIKNLLLEN--------------------------------IRDAKFCDKHED-----------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . *: * : * :.: . ..: . * : ::*. * : : . * : . ..* : :.*: :: . : .: . : : .. : : :* . :: . . . . :: : .: : * ..* . :: . : . ..: :*:::: :: : . : :* .** *:*: :. .: . : .* : . : : : * ..: : . . :: : :* . ", "identical_positions": 21, "similar_positions": 104, "identity": "1.17%" }, { "cls_id": "homologset.agr.SGD:S000005224", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O76062-1", "uniprot_id": "ERG24_HUMAN", "id": "O76062-1", "name": "Delta(14)-sterol reductase TM7SF2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPTQGPRAPLEFGGPLGAAALLLLLPATMFHLLLAAR---------SGPARLLGPPASLPGLEVLWSPRALLLWLAWLGLQAALYLLPARKVAEGQELKDKSRLRYPINGFQA----LVLTALLVGLGMSAGLPLGALPEMLLPLAFVATLTAFIFSLFLYMKAQVAPVSA----------LAPGGNSGNPIYDFFLGRELNP----RICFFDFKYFCELRPGLIGWVLINLALLMKEAELR-----------------GSPSLAMWLVNGFQLLYVGDALWHEEAVLTTMDITHDGFGFMLAFGDMAWVPFTYSLQAQFLLHHPQPLGLPMASVICLINATGYYIFRGANSQKNTFRKNPSDPRVAGLETISTATGRKLLVSGWWGMVRHPNYLGDLIMALAWSLPCGVSHLLP-YFYLLYFTALLVHREARDERQCLQKYGLAWQEYCRRVPYRIMPYIY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q71KT5-1", "uniprot_id": "ERG24_MOUSE", "id": "Q71KT5-1", "name": "Delta(14)-sterol reductase TM7SF2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSREASQAPLEFGGPLGVAALLILLPATMFHLLLAAR---------SGPARLLALPAYLPGLEELWSPWALLLLFIWLGLQVALYLLPARKVAEGLELKDKSRLRYPINGFQA----LVLTALLMGLGVSVGLPLGALPGMLLPLAFATTLTSFIFSLLLYAKALVAPASA----------LAPGGNSGNSMYDFFLGRELNP----RLGSFDFKYFCELRPGLIGWVFINLALLMQEAELR-----------------GSPSLAMWLVNGFQLLYVGDALWYEESVLTTMDIIHDGFGFMLVFGDLAWVPFTYSLQAQFLLYHPQPLGLPMALLICLLKVIGYYIFRGANSQKNTFRKNPSDPSVAGLETIPTATGRQLLVSGWWGMVRHPNYLGDLIMALAWSLPCGLSHLLP-YFYVLYFTALLVHREARDEQQCLQKYGRAWQEYCKRVPYRIIPYVY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08984-1", "uniprot_id": "LBR_RAT", "id": "O08984-1", "name": "Delta(14)-sterol reductase LBR", "aln": "---------------------------------MPGRKFADGEVVRGRWPGSSLYYEVEILSHDSTSQLYTVKYKDGTELELKESDIKPLKSFKQR-KSGSTSSSPSRRRSSRSRSRSRSRS--PGRAPKGSRRSVSASYQADAKEK---EMRREILQVKLTPLVLKPFANSVSVYNGEPEHMEKSATPPKNKQERVILSTEDSYIATQYSLRPRREEVKPKHRVRG-TNLVTRGPVPLG------------------------------------------------------TFQVTTPQRRDLEFGGVPGALLIMLGLPACVFLLLLQCA---------QKDPGLLQFPPPLPALRELWEARVCGVYLLWFFLQALFSLLPVGKVVEGTPLVDGRRLKYRLNGLYA----FILTSAAVGTAVFWDIELYYLYTHFLQFALAAIVFSVVLSVYLYARSLKVPRDE----------LSP-ASSGNAVYDFFIGRELNP----RIGAFDLKFFCELRPGLIGWVVINLVMLLAEMKVQE---------------RSAPSLAMTLVNSFQLLYVVDALWFEEALLTTMDIIHDGFGFMLAFGDLVWVPFTYSLQAFYLVNHPQDLSWPLTSVIIALKLCGYVIFRCANSQKNAFRKNPTDPKLAHLKTIPTSTWKSLLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHILP-YFYVIYFTALLIHREARDEHQCRRKYGLAWEKYCQRVPYRIFPYIY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U9G9-1", "uniprot_id": "LBR_MOUSE", "id": "Q3U9G9-1", "name": "Delta(14)-sterol reductase LBR", "aln": "---------------------------------MPSRKFVEGEVVRGRWPGSSLYYEVEILSHDNKSQLYTVKYKDGTELELKESDIKPLKSFKQR-KSGSISSSPSRRRGSRSRSRSRSRSRSPGRAPKGSRRSVSASHEGDVKEKKEKEMRREILQVKLTPLVLKPFGNSVSVYNGEPEHMEKNATPYKDKQERIILSTEDRYIVTQYSLRPRREEVKAKEIESEEQNLVTKGPAPLG------------------------------------------------------TFQVTTPQRKDLEFGGVPGAVLIMLGLPACVLLLLLQCR---------QKDPGLLHFPPPLPALHELWEPRVCGVYLLWFFVQALFHLLPVGKVAEGTPLVDGRRLQYRLNGLYA----FILTSAALGAAVFWGVELCYLYTHFLQLALAATGFSVLLSAYLYVRSLRAPREE----------LSP-ASSGNAVYDFFIGRELNP----RLGAFDLKFFCELRPGLIGWVVINLVMLLMEMKIQE---------------RAAPSLAMILVNSFQLLYVVDALWNEEALLTSMDIMHDGFGFMLAFGDLVWVPFTYSLQAFYLVSHPHDLSWPLASVIIALKLCGYVIFRCANSQKNAFRKNPTDPKLAHLKTIHTSTGKSLLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHLLP-YFYIIYFTALLIHREARDEHQCRRKYGLAWEKYCQRVPYRIFPYIY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14739-1", "uniprot_id": "LBR_HUMAN", "id": "Q14739-1", "name": "Delta(14)-sterol reductase LBR", "aln": "---------------------------------MPSRKFADGEVVRGRWPGSSLYYEVEILSHDSTSQLYTVKYKDGTELELKENDIKPLTSFRQR-KGGSTSSSPSRRRGSRSRSRS--RS--PGRPPKSARRSASASHQADIKEA------RREVEVKLTPLILKPFGNSISRYNGEPEHIERNDAPHKNTQEKFSLSQESSYIATQYSLRPRREEVKLKEIDSKEEKYVAK-ELAVR------------------------------------------------------TFEVTPIRAKDLEFGGVPGVFLIMFGLPVFLFLLLLMCK---------QKDPSLLNFPPPLPALYELWETRVFGVYLLWFLIQVLFYLLPIGKVVEGTPLIDGRRLKYRLNGFYA----FILTSAVIGTSLFQGVEFHYVYSHFLQFALAATVFCVVLSVYLYMRSLKAPRND----------LSP-ASSGNAVYDFFIGRELNP----RIGTFDLKYFCELRPGLIGWVVINLVMLLAEMKIQD---------------RAVPSLAMILVNSFQLLYVVDALWNEEALLTTMDIIHDGFGFMLAFGDLVWVPFIYSFQAFYLVSHPNEVSWPMASLIIVLKLCGYVIFRGANSQKNAFRKNPSDPKLAHLKTIHTSTGKNLLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHILP-YFYIIYFTMLLVHREARDEYHCKKKYGVAWEKYCQRVPYRIFPYIY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PP65-1", "uniprot_id": "A0A8M9PP65_DANRE", "id": "A0A8M9PP65-1", "name": "Delta(14)-sterol reductase LBR", "aln": "---------------------------------MPPARFQIGDTVMGRWPGSNLYYEVKVMSFDNKTRLYTVIYKDGTELELKESDITSVVIFQTAGRSRSRSRSPGRSPGRSSARSPGRPRRSRSRSPARTPRRASSRSTEVRKEK-----LKEVLEVRLTPVAMKHENNSSNSKSEKKEENNTAKAAPVVTEEKTETESENQ-TGGRYNLRRRKDQGDGK---AVELEKAVESEPLLQ------------------------------------------------------TKAPAAVKTADLEFGGRVGVLFLMFLLPVAVLVLLILCG---------QKDASLQSFPLELPALQSVWDCQVFGIVLLWLLFQAVLSLLPVGKLVEGMPLKNGKTLKYRINGFYA----LLLTAVAAGVAVYQEVDLSYIHAHFLQFYTSALLIATLLSIYLFIRSRWASKDE----------LAPGGNSGYIIYDFFMGRELNP----RIKSFDIKFFCEMRPGLMGWVLINFAMLLAEMKQQN---------------LENPSPAMLLVNIFQLLWVIDGLWHEEKLLTMMDIMYDGFGFMLTFGDLAFVPFTFTCQAYYLVNHPNELSVFWIITLIAMNGVGYYIFRKANSQKFAFRKNPSDPAVSHLKTIPTATGKSLIVSGLWGFVRHPNYLGDIIMALAWSLPCGFNNLVP-YFYLIYLVTLLVHRNARDERQCRKKYGSAWEEYCKAVPYRIFPRVY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32462-1", "uniprot_id": "ERG24_YEAST", "id": "P32462-1", "name": "Delta(14)-sterol reductase ERG24", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVSALNPRTTEFEFGGLIGALGISIGLPVFTIILNQMIRPDYFIKGFFQNFDIVELWNGIKPLRYYLGNRELWTVYCLWYGILAVLDVILPGRVMKGVQLRDGSKLSYKINGIAMSTTLVLVLAIRWKLTDGQLPELQYLYENHVSLCIISILFSFFLATYCYVASFIPLIFKKNGNGKREKILALGGNSGNIIYDWFIGRELNP----RLGPLDIKMFSELRPGMLLWLLINLSCLHHHYLKT-----------------GKINDALVLVNFLQGFYIFDGVLNEEGVLTMMDITTDGFGFMLAFGDLSLVPFTYSLQARYLSVSPVELGWVKVVGILAIMFLGFHIFHSANKQKSEFRQG----KLENLKSIQTKRGTKLLCDGWWAKSQHINYFGDWLISLSWCLATWFQTPLT-YYYSLYFATLLLHRQQRDEHKCRLKYGENWEEYERKVPYKIIPYVY", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8MLV1-1", "uniprot_id": "LBR_DROME", "id": "Q8MLV1-1", "name": "Lamin-B receptor", "aln": "MQHSPSTTTDHIHFAARFFDRNSYTMDRRLRRPRRTEDVSSGPLLAQSKQPSLLPVTRRTGSVTAAGATATATATAGPATRTRASPSRNKVVAPPSPDLGPRTRRSSRPRSSVGPLTGSGSGSSLPIKAAIKARTPIPEVSEVSSPIRLSTSNLPMTLTTNTSSGAPNKAFNTSSVNSGNSFSRTTTSSTTTTTERIEIRAEGDGEVDTDSIRKRITERLRRSVSKTISNLAGTPVTNTEEGSRYSRSVSRSVYDDEKSSKRSYSTGEEDIDEEDELEEDQFRSFNVTRKSATPAEISCRQLKAPREFGGWLGAFLFLLLLPTAVYYLTWSCT--------ARNACQFKHLNLGILLDVNYLTRQVFQPRVVGAFAAYQVVVFLLVALLPG-RRVHLTRETYKFNCLAVS---LTLLIASGVAEYLKYPVVTFVLRHYLRFCIFGLVGAFVAAAWSYWLVDTAKYNVLR-----QTLTNDYGRTGSFVVDFALGRQLNPKWLGRVDWKQFQYRLSLVTTLIYATCYIYQTLVWPQKPQLGEQEGYLYQAKYYWNNVNYDPATLFSASCLLFYVLDAIIFEHHLSSSFELQHEGYGCLLLLRYAATPYLLTAVTKYFYEQRVPISCWYAPLAVAALLSLGLLVKRFSCAYKYKYRLNSQSPIFANIETIHTYQGSRLLLSGMWGWVRQPNYLGDIVALLALAAPMALRPAWPPVLGLSLIILLLLHRATRANARNQARYHSSWQRYSTQVRSYILPRVY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **** *. : : **. * . . :: : * . * :* : . : . : : : . . : : . :* : *: :**:*** *: ::: .: . :: * . * : ::: *.: *. : : ::: :*:* :* : : : : : : * : : : * :* . . :::* * *: .* *. :: **:** : *: . . . . : **:** * : : :* *:.* * *:* :*", "identical_positions": 51, "similar_positions": 89, "identity": "6.73%" }, { "cls_id": "homologset.agr.SGD:S000005225", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BN63-1", "uniprot_id": "B0BN63_RAT", "id": "B0BN63-1", "name": "Activator of 90 kDa heat shock protein ATPase homolog 1", "aln": "MAKWGEGDPRWIVEERADATNVNNWHWTERDASNWSTEKLKTLFLAVRVENEEGKC--EVTEVNKLDGEASINNRKGKLIFFYEWTIKLNWTG--------TSK-SGVQYKGHVEIPNLSDENSVDEVEISVSL-AKDEPDTSLVALMKEDGVKLLREAVGIYISTLKTEFTQGMILPTVNGESVDPVGQPALKTE----------VCKAKCAPSKSQAKPVGVKIPTCKITLKETFLTSPEELYRVFTTQELVQAFTHAPAALEADRGGKFHMVDGNVTGEFTDLVPEKHIAMKWRFKSWPEGHFATITLTFIDKNGETELCMEGRGIPAPEEERTRQGWQRYYFEGIKQTFGYGARLF---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BK64-1", "uniprot_id": "AHSA1_MOUSE", "id": "Q8BK64-1", "name": "Activator of 90 kDa heat shock protein ATPase homolog 1", "aln": "MAKWGEGDPRWIVEERADATNVNNWHWTERDASNWSTEKLKTLFLAVRVENEEGKC--EVTEVNKLDGEASINNRKGKLIFFYEWTIKLNWTG--------TSK-SGVQYKGHVEIPNLSDENSVDEVEISVSL-AKDEPDTNLVALMKEDGVKLLREAVGIYISTLKTEFTQGMILPTVNGESVDPVGQPALKTE----------TCKAKSAPSKSQAKPVGVKIPTCKITLKETFLTSPEELYRVFTTQELVQAFTHAPAALEADRGGKFHMVDGNVTGEFTDLVPEKHIAMKWRFKSWPEGHFATITLTFIDKNGETELCMEGRGIPAPEEERTRQGWQRYYFEGIKQTFGYGARLF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95433-1", "uniprot_id": "AHSA1_HUMAN", "id": "O95433-1", "name": "Activator of 90 kDa heat shock protein ATPase homolog 1", "aln": "MAKWGEGDPRWIVEERADATNVNNWHWTERDASNWSTDKLKTLFLAVQVQNEEGKC--EVTEVSKLDGEASINNRKGKLIFFYEWSVKLNWTG--------TSK-SGVQYKGHVEIPNLSDENSVDEVEISVSL-AKDEPDTNLVALMKEEGVKLLREAMGIYISTLKTEFTQGMILPTMNGESVDPVGQPALKTE----------ERKAKPAPSKTQARPVGVKIPTCKITLKETFLTSPEELYRVFTTQELVQAFTHAPATLEADRGGKFHMVDGNVSGEFTDLVPEKHIVMKWRFKSWPEGHFATITLTFIDKNGETELCMEGRGIPAPEEERTRQGWQRYYFEGIKQTFGYGARLF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8N9S3-1", "uniprot_id": "AHSA2_MOUSE", "id": "Q8N9S3-1", "name": "Activator of 90 kDa heat shock protein ATPase homolog 2", "aln": "MAKWGQGDPRWIVEEREDGTNVNNWHWTERDATIWSKGKLRELLVGIAMENEAGRC--EISELKQVEGEASCNSRKGKLIFFYEWNIKLAWKG--------TVKESGAKHKGLIEIPSLSEENEINDTEVNVSK-KKGD-GEILKDLMRTTGTAKVREALGEYLKALKTEFTTGMILPTKAVATQELTLQRKLNEN----------KLQ-------ASPVALGVRIPTVALHLTELFDTTVEQLYSIFTVKELVQKFSKSPAVLEAERGGKFQMFDGNISGEYVELVTNRKIIMKWRCRNWPEEHYATVELNFVPAPGQTELQLDCKGVPVCKEENMKFCWQKQHFEEIKGLLELTAQNA---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K7W5-1", "uniprot_id": "A0A0G2K7W5_RAT", "id": "A0A0G2K7W5-1", "name": "", "aln": "MAKWGQGDPRWIVEEREDGTNVNNWHWTERDATVWSKGKLRELLVGLAMENEAGRC--EISELKQVEGEASCNSRKGKLIFFYEWNIKLAWKG--------TVKESGAKHKGLIEIPSLSEENEVNDTEVNVSK-KKGD-GEILKDLMRTTGTAKVREALGEYLKALKTEFTTGMILPTKAGATQALTLERKLTEN----------ALQ-------ASPVALGVRIPTVALHLTELFDTTVEQLYSIFTVKELVQGFSKSPAVLEAEKGGKFQMFDGNITGEYVELVTNRKIIMKWRCRNWPEEHYATVELNFVPAPGQTELQLDCKGVPVCKEEHMKFCWQKQHFEEIKGLLQLTTQNA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q719I0-1", "uniprot_id": "AHSA2_HUMAN", "id": "Q719I0-1", "name": "Putative activator of 90 kDa heat shock protein ATPase homolog 2", "aln": "MAKWGQGNPHWIVEEREDGTNVNNWRWTERDATSLSKGKFQELLVGIVVENDAGRG--EINELKQVEGEASCSSRKGKLIFFYEWNIKLGWKG--------IVKESGVKHKGLIEIPNLSEENEVDDTEVSLSK-KKGD-GVILKDLMKTAGTAKVREALGDYLKALKTEFTTGMILPTKAMATQELTVKRKLSGN----------TLQVQ----ASSPVALGVRIPTVALHMMELFDTTVEQLYSIFTVKEL----------------------------------TNKKIIMKWRCGNWPEEHYAMVALNFVPTLGQTELQLK-EFLSICKEENMKFCWQKQHFEEIKGSLQLTPLNG---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V9Q4-1", "uniprot_id": "Q9V9Q4_DROME", "id": "Q9V9Q4-1", "name": "Activator of Hsp90 ATPase AHSA1-like N-terminal domain-containing protein", "aln": "MAKWGEGDPRWIVEERPDATNVNNWHWTEKNATPWSKDRLHQLFQDFKIGQSDIEC--AVDSVDKCSGEATVNNRKGKLIFFYEWELVLKWSGK-------LLKNSKLIHKGKLTIPNLSEENELADVEITVTIDESNDESETLKQFMYNVGRDRVRQQLASYIRELKEEYSKNLILPKKGDEAGAGNTVANFKDANNTRNAAQNIALNSSVAAPRLKNSGIGCKLDVRTLSMTEEFHCSANDLYNALTKPEMVTAFTRAPAKVDAVRGGEFILYGGNVLGKFEELVPEKKIQQSWRLKNWTSGHYSNVVIELEETSSSTMMSLKQTGIPASEFDAMKTNWYRYYWHSIKQTFGFGTSISDAL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53834-1", "uniprot_id": "HCH1_YEAST", "id": "P53834-1", "name": "Hsp90 co-chaperone HCH1", "aln": "----------------MVVLNPNNWHWVDKNTLPWSKDYLNGKLTSLSTVSSDGKSKIELTQVSSITGDSNVSQRKGKPICYFDLQLSMNVKVTNLDTNKDDEDDDGILADGKLEIPEFMHD----ESDIPILS----QGFDAFDGLVRSEFVPKVVETLLKYQDDLIKEHSKDIQV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ***:*.:::: *. :. : . .. . : .:.. *::. ..**** * ::: : : . . . .* : **.: .: : :: : : : :: : : : * * *.: .: : ", "identical_positions": 18, "similar_positions": 54, "identity": "4.96%" }, { "cls_id": "homologset.agr.SGD:S000005228", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A254-1", "uniprot_id": "A0A8I6A254_RAT", "id": "A0A8I6A254-1", "name": "Large ribosomal subunit protein uL15m", "aln": "MAGMAFGRGT-SLDLLRS------------LPRVS-------------------------LANLKPSLNSRKRE-RRPRDRRR--GRKCGRGHKGERQRGTRPRLGFEGGQTPFYIRIPKYGFNEGHSFRHQYQPLSLRRLQYLIDLGRVDPTQPIDLTQLVNGRGVTIQPLKRDYGVQLVEEGADTFQAKVNIEVQMASELAIAAIEKNGGVVTTAFYDPRSLEILCKPVPFFLRGQPIPKRMLPPEA-LVPYYTDAKNRGYLADPAKFPEARLELAMKYG--YVLPDVTKDELFRMLSTRKDPRQIFFGLAPGWIVNMADKKILKPTDENLLKYYSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CPR5-1", "uniprot_id": "RM15_MOUSE", "id": "Q9CPR5-1", "name": "Large ribosomal subunit protein uL15m", "aln": "MAGTARGCGT-SLDLLRS------------LPRVS-------------------------LANLKPSPNSRKRE-RRPRDRRR--GRKCGRGHKGERQRGTRPRLGFEGGQTPFYIRIPKYGFNEGHSFRHQYQPLSLRRLQYLIDLGRVDPTQPIDLTQLVNGRGVTIQPLKRDYGVQLVEEGADTFQAKINIEVQLASELAIAAIEKNGGVVTTAFYDPRSLEILCKPIPFFLRGQPIPKRMLPPES-LVPYYTDAKNRGYLADPAKFPEARLELAMKFG--YVLPDITKDELFRMLSARKDPRQIFFGLAPGWVVNMADKKILKPTDENLLKYYSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P015-1", "uniprot_id": "RM15_HUMAN", "id": "Q9P015-1", "name": "Large ribosomal subunit protein uL15m", "aln": "MAGPLQGGGARALDLLRG------------LPRVS-------------------------LANLKPNPGSKKPE-RRPRGRRR--GRKCGRGHKGERQRGTRPRLGFEGGQTPFYIRIPKYGFNEGHSFRRQYKPLSLNRLQYLIDLGRVDPSQPIDLTQLVNGRGVTIQPLKRDYGVQLVEEGADTFTAKVNIEVQLASELAIAAIEKNGGVVTTAFYDPRSLDIVCKPVPFFLRGQPIPKRMLPPEE-LVPYYTDAKNRGYLADPAKFPEARLELARKYG--YILPDITKDELFKMLCTRKDPRQIFFGLAPGWVVNMADKKILKPTDENLLKYYTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DGM3-1", "uniprot_id": "RM15_DANRE", "id": "Q6DGM3-1", "name": "Large ribosomal subunit protein uL15m", "aln": "MSLIKKPGGK-TIEVVKN------------LPRIT-------------------------LANLRPNPGAKTLEKRRGRGMHG--GNRSGWGHKGERQRCNRPRLGFEGGQTPFYLVIPKYGYNANHSRQPQYPPLSLRRLQYLIDLGRIDPSQPIDLTQLVNGRGVEIQPQKRDYGVQLVDEGADIFCAKVNLEVQAASEKAIAAVERNGGVITTSYYDPRSLQILIKPVPFFMPGEPIPKRLFPGED-LLPYYTDANNRGYLADPDKIQTARMDLAKKYG--YSIPDISKDTLFEMLVQRKNPRHIFFGLSPGWVVNMADKKILKPTDDKVLQYYGS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPF6-1", "uniprot_id": "Q9VPF6_DROME", "id": "Q9VPF6-1", "name": "Large ribosomal subunit protein uL15m", "aln": "MAHLRETSDK-ALKLLRT------------LPRVQ-------------------------IGNLRPNPNSKQND-KRGRAQHG--GDKHGAGNKGSGQRQNFMRLGYETGNQPFYLRFPYEPYYKGHHLKRQYPPISLLQLQVLIDTNRIDISQPIDISTLCNSGLLKLKPAEMEYGFQLTDDGLDNFQAKINIEVQHASEAVIAAIEKNGGVIRTAYYDPRSLHMLANPKKWFEKGVPIPSRMLPPQD-AVDYYTDPKNRGYLANPEAISQDRLVLAQKYG--YQLPKIEEDSAYEMLTTAKDPRQVFYGLEPGWLINIVDKTIIKRKQ---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36520-1", "uniprot_id": "RM10_YEAST", "id": "P36520-1", "name": "Large ribosomal subunit protein uL15m", "aln": "MKAERQTGLRNSFTTVIGRKLINTFVPSMMLTSVAGNDIFFRGLFKSPVLAFQSYRYVSILGQLKPSDGSTKSFKRLGRGPSSGLGKTSGRGQKGQKARG-KVKSWFEGGQTPIYKLFPKIGFTN--VGAKPLKELNLKRIQWFHDKNRLHLQ-PGEVLDMNKMRKLGLVTGPIKYGVKILASGKFHYNLPIALEASRASAKAIAAIEKAGGKFTARYYTPLGLRAHLNPQWFLEKRGRVPLQARPTKRRDIDFYSKEEKRGYLVMEKDKLLQDIKEAQNKGSRHFLKQNVKKSSLEIELEELSP-------EKDWVPVVSNSKVMNIKALDH------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: : *. : :.:*:*. .: : * * * *:**. * : :* *: *:* :* : :.* ::* : * .*:. * :: : : : : . .**.:: .* : : :*.. ** .***:*: ** . : :* * .* :* :: :* : * : : :*:. ::****. : * : * : : . :. .: .* .*: : :..::: . ", "identical_positions": 48, "similar_positions": 86, "identity": "14.16%" }, { "cls_id": "homologset.agr.SGD:S000005230", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGC0-1", "uniprot_id": "HTSF1_MOUSE", "id": "Q8BGC0-1", "name": "17S U2 SnRNP complex component HTATSF1", "aln": "MSGNNLSGNDEFDEQLRMQELYGGDPKEGDTQNEPSGEAHSLGQPPDDTPYEWDLDKKAWFPKITEDFIATYQANYGFSSDGASSSTANVQDANTKAVEEPPQKEVPETPDSKRKGEKRKAESGWFHVEEDRNTNVYVSGLPPDITVDE-FIQLMSKFGIIMRDPQTEEFKVKLYKDDQGNLKGDGLCCYLKKESVELALKLLDEDEIRGYKLHVEVAKFQLKGEYDASKKKKKCKDYKKKLSLQQKQLDWRPERR-------AGPNRLRHERVVILKNMFHPMDFEDDPLVLNEIREDLRVECSKFGQIRKLLLFDRHPDGVASVSFREPEEADHCIQTLDGRWFGGRQITAQAWDGTTDYQVEETSREREERLRGWEAFLNAPEASRGLRRMDSIAGSERPGPSRMRHFSEHPSMSNMKAQEATTGMAFEETIDENKFEKAEE-GGESEGDASEKDAKEGGSDGDHPEREG------------------GEGCSKKENEEGCPERALE-------PEEGNPQTEAQENGPEREARKKS-KMDYEKNGFSKESEDNDLGKESEGEDSLKKESEDDDSEEESEEDSSEKQSQDGSDKEIEENGVKKDVDQDVSDKEFPEDVE-KESEENETDKSEFDE-GSERVLDEEGSEREFEEDSDEKEEEGDDDEE-EVVYERVFDDDSDDIEEEEEADEKECEDADDKEEDNDIDEKLFDDSDEKEDEEDTDGKKDDDASDKVFEDN-SNEKLFDEEEGPNEKLFDDSDERGTVG--NVKEDGSQSTDSSFALSSSDDDDDEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A997-1", "uniprot_id": "D4A997_RAT", "id": "D4A997-1", "name": "17S U2 SnRNP complex component HTATSF1", "aln": "MSGSNLSGNDEFDEQLRMQELYG-DPKEGDTQNEPSGETDSLGQPPDDTPYEWDLDKKAWFPKITEDFIASYQANYGFSGDGAPSSTGNVQDANTKTVEEPPQKEIPETTDSKKRGEKRKAESGWFHVEEDRNTNVYVSGLPPDITVDE-FIQLMSKFGIIMRDPQTEEFKVKLYKDDQGNLKGDGLCCYLKKESVELALKLLDEDEIRGYKLHVEVAQFQLKGEYDASKKKKKCKDYKKKLSLQQKQLDWRPERR-------AGPNRLRHERVVILKNMFHPMDFEDDPLVLNEIREDLRVECSKFGQIRKLLLFDRHPDGVASVSFREPEEADNCIQTLDGRWFGGRQITAQAWDGTTDYQVEETSREREERLRGWEAFLNAPEANRGLQRMDSICGSERPGPSRVRHFSEHPSMSNMGAQEATTGMAFEETIDENKFEKAEDDGGESEGDASEKDAKEGESDGDYPERESDEGCSKRQCEEGCPDRESGEGCSKRESGEGCPERELE-------LEEGNPKKESQENGPERESKKKG-KENYEKNGLAKESEDNDLNRESEGEDSPKKESEEDDSERESEEDSSEKQSENGSDKELEENGVKKDFDQDASDKEFPENVE-KESEENETDKSEFDE-GSERVLGEEGSEREFEEDSDEKEEEEDDDEEKEVVYERVFEDDSDDFEEEEEAYEKECEDADEKEEDDDVDEKVFDDSDEKEDEEDTDVRKDDDASDKVFEDN-SNEKLFNEEEGPNEKLFDDSDERGTVG--NVKEDGSQSTDSSFALSSSDDDGDEV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43719-1", "uniprot_id": "HTSF1_HUMAN", "id": "O43719-1", "name": "17S U2 SnRNP complex component HTATSF1", "aln": "MSGTNLDGNDEFDEQLRMQELYG-DGKDGDTQTDAGGEPDSLGQQPTDTPYEWDLDKKAWFPKITEDFIATYQANYGFSNDGASSSTANVEDVHARTAEEPPQEKAPEPTDARKKGEKRKAESGWFHVEEDRNTNVYVSGLPPDITVDE-FIQLMSKFGIIMRDPQTEEFKVKLYKDNQGNLKGDGLCCYLKRESVELALKLLDEDEIRGYKLHVEVAKFQLKGEYDASKKKKKCKDYKKKLSMQQKQLDWRPERR-------AGPSRMRHERVVIIKNMFHPMDFEDDPLVLNEIREDLRVECSKFGQIRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQVEETSREREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTED-GGEFEEGASENNAKESS-----PEKEA------------------EEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESED-DLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEED-------TYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDE-DADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGSVEEGPLSTGSSFILSSDDDDDDI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53830-1", "uniprot_id": "CUS2_YEAST", "id": "P53830-1", "name": "Cold sensitive U2 snRNA suppressor 2", "aln": "---------------------------------------------------------------------------------------MDADELELKGHLKKLKKEELLRRKQLKESNLQKRELEYNNAS--KNTSIYISGLPTDKTTKEGLTEQFCKYGMIRTN-RDGEPLCKLYVNDKGAFKGDALITYSKEESVTLAIEMMNESIFLGKQIRVERAQFQNKEGDNMHGKENDLKEFNGPEPPIKRLKKAKSEGEGEVIDYNDDESLAKADRTVIFANVFNIYKSYTN-DDINDIQEDLLEGCEEIGQVDSISVSPNK--GEATVVFKNNKVALQCCKIMTGRYFDGQKLLAFISG---DENTSSTSDKNED-----------SEVEDDLI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:: . : : ::: . :..: :* * : :.. :**.:*:****.* *..* : : :.*:*:* : : * *** :::* :***.* * *.*** **:::::*. : * :::** *:** * : *::. *::: . :: . :.* . . . : :*.**: *:*: . : :*:*:*** *.::**: .: : .: * *:* *:: : * * : : **:*.*::: * . * :...** :.*: .*.. .* ", "identical_positions": 72, "similar_positions": 111, "identity": "9.02%" }, { "cls_id": "homologset.agr.SGD:S000005231", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ABY2-1", "uniprot_id": "COPG2_RAT", "id": "D4ABY2-1", "name": "Coatomer subunit gamma-2", "aln": "-----MIKKFDKKDEESGSGSNPFQHLEKSAVLQEAR-IFNETPINPRRCLHILTKILYLLNQGEHFGTMEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKRWINEAQEAAS----------------SDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSG-LKSQFAYCMLIRIASRLLKES----EDGHESPLFDFIESCLRNKHEMVIYEAASAIIHLPNCTARELAP-----AVSVLQLFCSSPKPALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAIS-LCQKYPRKHSVMMTFLSNMLRD-DGGFEYKKAIVDCIISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPVPSKYIRFIFNRVVLENEAVRAAAVSALAKFGAQ--NESLLPSILVLLQRCMMDTDDEVRDRATFYLNVLQQRQMA---LNATYIFNGLTVSIPGMEKALHQYTLEPSE---KPFDMKSIP-------------------------------LAMAPVFEQKSEITLVTPK--PEKLAPSRQDIFQEQLAAIPEFVNLGPLFKSS-EPVQLTEAETEYFVRCVKHMFTDHIVFQFDCTNTLNDQLLEKVTVQMEPSD----SYEVLCCVPAPSLPYNQPGICYTLVRLPDEDPTA------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXK3-1", "uniprot_id": "COPG2_MOUSE", "id": "Q9QXK3-1", "name": "Coatomer subunit gamma-2", "aln": "-----MIKKFDKKDEESGSGSNPFQHLEKSAVLQEAR-IFNETPINPRRCLHILTKILYLLNQGEHFGTMEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAVERYMKQAIVDKVSSVASSALVSSLHMMKISYDVVKRWINEAQEAAS----------------SDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSG-LKSQFAYCMLIRIASRLLKES----EDGHESPLFDFIESCLRNKHEMVIYEAASAIIHLPNCTARELAP-----AVSVLQLFCSSPKPALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAISALCHKYPRKHSVMMTFLSNMLRD-DGGFEYKKAIVDCIISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPVPSKYIRFIFNRVVLENEAVRAAAVSALAKFGAQ--NESLLPSILVLLQRCMMDTDDEVRDRATFYLNVLQQRQMA---LNATYIFNGLTVSIPGMEKALHQYTLEPSE---KPFDMKSIP-------------------------------LAMAPVFEQKSEITLVTPK--PEKLAPSRQDIFQEQLAAIPEFMNLGPLFKSS-EPVQLTEAETEYFVRCVKHMFTDHIVFQFDCTNTLNDQLLEKVTVQMEPSD----SYEVLCCIPAPSLPYNQPGICYTLVRLPDEDPTAVAGTFSCTMKFTVRDCDPNTGVPD--EDGYDDEYVLEDLEVTVSDHIQKILKPNFAAAWEEVG--DAFEKEETFALSSTKTLEEAVNNIITFLGMQPCERSDKVPENKNSHSLYLAG--VYRGGYDLLVRSRLALADGVTMQVTVRSKERTPVDVILASVG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBF2-1", "uniprot_id": "COPG2_HUMAN", "id": "Q9UBF2-1", "name": "Coatomer subunit gamma-2", "aln": "-----MIKKFDKKDEESGSGSNPFQHLEKSAVLQEAR-IFNETPINPRRCLHILTKILYLLNQGEHFGTTEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKRWINEAQEAAS----------------SDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSG-LKSQFAYCMLIRIASRLLKET----EDGHESPLFDFIESCLRNKHEMVIYEAASAIIHLPNCTARELAP-----AVSVLQLFCSSPKPALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAISALCQKYPRKHSVMMTFLSNMLRD-DGGFEYKRAIVDCIISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPVPSKYIRFIFNRVVLENEAVRAAAVSALAKFGAQ--NESLLPSILVLLQRCMMDTDDEVRDRATFYLNVLQQRQMA---LNATYIFNGLTVSVPGMEKALHQYTLEPSE---KPFDMKSIP-------------------------------LAMAPVFEQKAEITLVATK--PEKLAPSRQDIFQEQLAAIPEFLNIGPLFKSS-EPVQLTEAETEYFVRCIKHMFTNHIVFQFDCTNTLNDQLLEKVTVQMEPSD----SYEVLSCIPAPSLPYNQPGICYTLVRLPDDDPTAVAGSFSCTMKFTVRDCDPNTGVPD--EDGYDDEYVLEDLEVTVSDHIQKVLKPNFAAAWEEVG--DTFEKEETFALSSTKTLEEAVNNIITFLGMQPCERSDKVPENKNSHSLYLAG--IFRGGYDLLVRSRLALADGVTMQVTVRSKERTPVDVILASVG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PUE4-1", "uniprot_id": "COPG2_DANRE", "id": "Q9PUE4-1", "name": "Coatomer subunit gamma-2", "aln": "-----MIKKFDKKDEESGSGSNPFQHLEKSAVLQEAR-IFNETPINPRRCLHILTKIIYLLNQGEHFGTTEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMANISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDTTMLQAIERYMKQAIVDKVPSVSSSALVSSLHMVKMSFDVVKRWVNEAQEAAS----------------SDNIMVQYHALGLLYHLRKNDRLAVTKMLNKFTKSG-LKSPFAYCMMIRIASKLLEET----EGGHDSPLFDFIESCLRNKHEMVVYEAASAIVHMPNCTARELAP-----AVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAISALCQKYPRKHSVMMNFLSNMLRD-DGGFEYKRAIVDCIISIIEENPESKETGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPTPSKYIRFIFNRVVLESEAVRAAAVSALAKFGAQ--NDDLLPSVLVLMQRCMMDSDDEVRDRATFYMNVLQQKQKA---LNAAYIFNGLSVSVLGLEKSLHQYTLEPSE---KPFDMKTVP-------------------------------LATAPITEHKTEIAPVATSKLPEKLAPSRQDIYQEQLSAIPEFQGLGPLFKSS-EPVQLTEAETEYVVRCIKHTFANHMIFQFDCTNTLNDQLLQKVLVQMEPSE----SYEVLHYVPAANLPYSQPGSCYSLVRLPEDDPTAVSCTFSCTMKYLVRDCDPNTGEPD--DDGYDDEYVLEDLEVTVADHIQKVLKPNFAAAWDEVG--DECEKEETFALATVRTLDEAVNNIVSFLGMQPCERSDKVPENKNSHVLFLAG--VFRGGHDVLVRARLALADGVTIQVTVRSTDDNVVDVILASVG-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9QZE5-1", "uniprot_id": "COPG1_MOUSE", "id": "Q9QZE5-1", "name": "Coatomer subunit gamma-1", "aln": "-----MLKKFDKKDEESGGGSNPLQHLEKSAVLQEAR-VFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQAVERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNEAQEAAS----------------SDNIMVQYHALGLLYHVRKNDRLAVSKMISKFTRHG-LKSPFAYCMMIRVASKQLEEE----DGSRDSPLFDFIESCLRNKHEMVVYEAASAIVNLPGCSAKELAP-----AVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRLMKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLRE-EGGFEYKRAIVDCIISIIEENSESKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPKTNNPSKYIRFIYNRVVLEHEEVRAGAVSALAKFGAQ--NEEMLPSILVLLKRCVMDDDNEVRDRATFYLNVLEQKQKA---LNAGYILNGLTVSIPGLEKALQQYTLEPSE---KPFDLKSVP-------------------------------LATTPMAEQRPESTATAAVKQPEKVAATRQEIFQEQLAAVPEFQGLGPLFKSSPEPVALTESETEYVIRCTKHTFSDHLVFQFDCTNTLNDQTLENVTVQMEPTE----AYEVLSYVPARSLPYNQPGTCYTLVALPTEDPTAVACTFSCVMKFTVKDCDPNTGEID--EEGYEDEYVLEDLEVTVADHIQKVMKVNFEAAWDEVG--DEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPENKNTHTLLLAG--VFRGGHDILVRSRLLLLDTVTMQVTARSSEELPVDIILASVG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4AEF8-1", "uniprot_id": "COPG1_RAT", "id": "Q4AEF8-1", "name": "Coatomer subunit gamma-1", "aln": "-----MLKKFDKKDEESGGGSNPLQHLEKSAVLQEAR-VFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQAVERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNEAQEAAS----------------SDNIMVQYHALGLLYHVRKNDRLAVSKMISKFTRHG-LKSPFAYCMMIRVASKQLEEE----DGSRDSPLFDFIESCLRNKHEMVVYEAASAIVNLPGCSAKELAP-----AVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRLMKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLRE-EGGFEYKRAIVDCIISIIEENSESKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPKTNNPSKYIRFIYNRVVLEHEEVRAGAVSALAKFGAQ--NEEMLPSILVLLKRCVMDDDNEVRDRATFYLNVLEQKQKA---LNAGYILNGLTVSIPGLEKALQQYTLEPSE---KPFDLKSVP-------------------------------LATTPMTEQRPESTSTAAVKQPEKVAATRQEIFQEQLAAVPEFQGLGPLFKSSPEPVALTESETEYVIRCTKHTFSDHLVFQFDCTNTLNDQTLENVTVQMEPTE----AYEVLSYVPVRSLPYNQPGTCYTLVALPKEDPTAVACTFSCVMKFTVKDCDPNTGEID--EEGYEDEYVLEDLEVTVADHIQKVMKVNFEAAWDEVG--DEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPENKNTHTLLLAG--VFRGGHDILVRSRLLLLDTVTMQVTARSSEELPVDIILASVG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y678-1", "uniprot_id": "COPG1_HUMAN", "id": "Q9Y678-1", "name": "Coatomer subunit gamma-1", "aln": "-----MLKKFDKKDEESGGGSNPFQHLEKSAVLQEAR-VFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNEAQEAAS----------------SDNIMVQYHALGLLYHVRKNDRLAVNKMISKVTRHG-LKSPFAYCMMIRVASKQLEEE----DGSRDSPLFDFIESCLRNKHEMVVYEAASAIVNLPGCSAKELAP-----AVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRLMKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLRE-EGGFEYKRAIVDCIISIIEENSESKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPKTTNPSKYIRFIYNRVVLEHEEVRAGAVSALAKFGAQ--NEEMLPSILVLLKRCVMDDDNEVRDRATFYLNVLEQKQKA---LNAGYILNGLTVSIPGLERALQQYTLEPSE---KPFDLKSVP-------------------------------LATAPMAEQRTESTPITAVKQPEKVAATRQEIFQEQLAAVPEFRGLGPLFKSSPEPVALTESETEYVIRCTKHTFTNHMVFQFDCTNTLNDQTLENVTVQMEPTE----AYEVLCYVPARSLPYNQPGTCYTLVALPKEDPTAVACTFSCMMKFTVKDCDPTTGETD--DEGYEDEYVLEDLEVTVADHIQKVMKLNFEAAWDEVG--DEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPDNKNTHTLLLAG--VFRGGHDILVRSRLLLLDTVTMQVTARSLEELPVDIILASVG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8I0G5-1", "uniprot_id": "COPG_DROME", "id": "Q8I0G5-1", "name": "Coatomer subunit gamma", "aln": "MNYFSLTSHKKHRGHPSAGPSNAYQNLEKTSVLQETR-TFNETPVNPRKCIHILTKILYLINQGEQLVAREATDCFFAMTKLFQSKDVVLRRMVYLGIKELSSIAEDVIIVTSSLTKDMTGKEDLYRAAAIRALCSITDNTMLQAVERYMKQCIVDKNAAVSCAALVSSLRLANTAGDVVKRWANEAQEALN----------------SDNIMVQYHALGLLYHIRKSDRLAVSKLVNKLTRGS-LKSPYAVCMLIRIACKLIEEEDIPSEELSDSPLFTFIESCLRHKSEMVIYEAAHAIVNLKNTNPRMLSP-----AFSILQLFCSSPKATLRFAAVRTLNKVAMTHPAAVTTCNLDLEGLITDSNRSVATLAITTLLKTGAESSVERLMKQISTFVAEISDEFKVVVVQAICALCTKYPRKHTVLMNFLSGMLRE-EGGLEYKTSIVDTIITIIEENADAKESGLSHLCEFIEDCEHVSLAVRILHLLGKEGPFAATPSKYIRFIYNRVILESPIVRAAAVTAMAQFGAS--CPALLSNILVLLGRCQMDPDDEVRDRATYYLSILNSERPE---LYKNYIIERENCSLALLEKSLVEHLNGDVD---TRFDISIVP-------------------------------KAAIVKPVIANDVMLVTSS-APRPPKITREEESAARLAQLPGIQVLGPIHRST-APIQLTESETEYTVQCIKHIFGQHVVFQFDCLNTLSDQILENVRVELTLPE----GFTTRAVIPCPKLPYNDLQTTFVIVEFPPDAANSIA-TFGATLRFVVKDCDPNTGEPES-EEGYDDEYMLEDLELTVADQIQKTRKNNFQVSWDAADSEEWLQAEDTFVLSAVTTLQDAVNTIVKILGLGAANLSENVPEGTHLHTLLCSG--TFRGGAEILVRAKLALSEGVTLNLTVRSTDQDVAELITAAIG-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32074-1", "uniprot_id": "COPG_YEAST", "id": "P32074-1", "name": "Coatomer subunit gamma", "aln": "-----MSAHTYKKFENSTSG----DLPDKMTIYQDCMNTFNESPVNSKRCRLLISRLLRLLAQGETFPQNEATALFFSISKLFQHQNDPLRQAVYLAIKELSGISEDVLMATSSIMKDVQNGSDLIKPDAIRSLTYVLDESTAFSAERLLKSAVVSRHPSISSAALCTSYHLLPISEVTIRRFTNETQEAVLDLKQFPNQHGNSEYYPNSTYISQYHALGLLYQLKKTDKMALLKLVRHFSENNSMKNQLAKVELVKIVNDLIYRD-----PQLFSQFRPLLSDWLSNKFESVQLETAKLITSFATRNSRLVAPELYAAAISALQSLLTVPRVSSRFAALRILNRISMVSPEKIVVCNPELESLINDSNRNISTYAITTLLKTGTSKNISSLISTITNFIHDVSDDFKIIIIDAVRTLSLNFPQEWKSILNFLIDVLKNSEGGFKFKNSIVEALIDIVSFVPQSKELALENLCDFIEDCEFNEILVRILHLLGKEGPSAPNPSLYVRHIYNRVVLENSIIRSAAVVALSKFALTKNDPTLYESIISLLKRIANDKDDEVRDRATIALEFIDSARNKDDVIAQNLIESKYFYDIPSLESKLSSYISSNTDSFATAFDVNQVRKFTEDEMKAINLKRKQEQIFNQKSETTLDTTPEAESVPEKRADANSFAGPNLDDHQEDLLATKYADELLSIEQIKPFGQLVNSS-RAISLTEPEAEFVVRGVKHLFKDNVVLQFNITNTLTDIALDNVSVVCTPEISDEAELEELFTLQVDRLLPSEEAACYVAFKKLD---EIVMEGFLNNLTFTTKEINPDTNEPFDGDEGFQDEYEIDSIFLNAGDYVKSSFTGNFSATFDELP----CEEVAVFNIQEDLSIQEVVDKIILNSSCLPVESTQFAPSDSNSHTLKLFGKSALTGSKVALQIKMIKSSKGLALKVHGKGEDSLLCSDLVNGLMQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: . * . : :* :: *: ***:*:*.::* :::::: *: *** : *** **::::*** :: **: ** ***:: *:***::.***: **: . .* : *:*:* : * : : ** :*..:*.: .:::.:** :* :: : .::*: **:*** ... : ******:**:::*.*::*: *:: :.:. . :*. * ::::. : . * : ::.. * :* * * *:* * : ..: ::* *.* ** : : *: : *:**:* **:::* * :..** :**.*:.****.::* *********:...:. *:. *:.*: ::**:**:::::*: *. ::*:: ::.** :*:: :**:::* :**: :* *:. .::** .* :**:******. : .:******:*** : ** *:*.*:***:** :*:.** *:::*. : .:: *: * * *:******* :..::. : : * . .: :* * .: : . **:. : : : .* : : :* : .*: .: ***.*:*: :: ** * :::::**: ***.* *::* * : * .: : . ", "identical_positions": 202, "similar_positions": 247, "identity": "21.11%" }, { "cls_id": "homologset.agr.SGD:S000005232", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PQL2-1", "uniprot_id": "CNOT9_RAT", "id": "Q5PQL2-1", "name": "CCR4-NOT transcription complex subunit 9", "aln": "-----------------------------MHSLATAAPVPTA-LAQVDR------------------------------------------------------EKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSK-EPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWLAQLVKNLQEGQVTDPRGIPLPPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKY0-1", "uniprot_id": "CNOT9_MOUSE", "id": "Q9JKY0-1", "name": "CCR4-NOT transcription complex subunit 9", "aln": "-----------------------------MHSLATAAPVPTA-LAQVDR------------------------------------------------------EKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSK-EPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWLAQLVKNLQEGQVTDPRGIPLPPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92600-1", "uniprot_id": "CNOT9_HUMAN", "id": "Q92600-1", "name": "CCR4-NOT transcription complex subunit 9", "aln": "-----------------------------MHSLATAAPVPTT-LAQVDR------------------------------------------------------EKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSK-EPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWLAQLVKNLQEGQVTDPRGIPLPPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NWL4-1", "uniprot_id": "CNOT9_DANRE", "id": "Q6NWL4-1", "name": "CCR4-NOT transcription complex subunit 9", "aln": "-------------------------------MLATGATVSTAGLAQVDR------------------------------------------------------EKIYQWINELSSPETRENALLELSKKRESVTDLAPMLWHSCGTIAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHVETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSK-EPSARLLKHVVRCYLRLSDNSRAREALRQCLPDQLKDTTFAQVLKDDSTTKRWLAQLVKNLQEGQVTDPRGIPLPTQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLF2-1", "uniprot_id": "Q9VLF2_DROME", "id": "Q9VLF2-1", "name": "CCR4-NOT transcription complex subunit 9", "aln": "-------------------------------MSAEPSPVMSP-QQQAER------------------------------------------------------EKVYQLIIELAYPATRETALLELSKN--TYADLAPMLWKSVGTTCTLLQEIVNIYPIITTPVLKANQSNRVCYALTLLQCVASHPETRPAFLRDQIPMYLYPFLSTTFKSRPFEQLRLTTLGVINALAETGDTEVLIFLIWSEVVPHCLTNMVRGSKLTKIAATSILEKILLDEMGLTYICENHDRFSQVAITLGKMVIHMLK-FPCLRVLKHVVRCYLLLTENARARSALRVCLPDLLRDGTFTSLVQHDTCTKQWLQMLLKNLQTNAVN-PMGSS----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53829-1", "uniprot_id": "CAF40_YEAST", "id": "P53829-1", "name": "Protein CAF40", "aln": "MFSAQKPIYGNGAGVNMGGGGPSTNNPGSMSMPGVPTSMGPGMNQQIPSGGPMLMGNTPNNNNSNENGENNGNNGNNGGNDANATRNNPNMVNNRGAVHALDDPNVYHWICQLTYGPQKEQALLELGRKREQFDDLAVVLWSSFGVMTSLLNEIISVYPMLQPQMLSNNLSNRVCNALVLLQCVASHPETKHLFLQAHIPLFLFPFLNTTSRQRTFEYLRLTSLGVIGALVKNDSQDVITFLLRTDIVPLCLRIMESSSELSKTVAIFILQKILLDDVGLQYICATLERFYAVTNVLKDMVEHLTVSTPPGRLLKHIIRCYLRLSDDLEARRLLKIVLPAKLRDNTFTEVLRDDVGSKRCLAQLLLTLNEETS-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.: . * ::*: * :*: :* *****.:: *** :** * *. :**:**:.:** : . *. : ***** **.******** **: ** :**::*:*** *. : *.** ****:****.**.:... :*: **: ::::* ** * .*:*:* .* **:*****: ** *** . :** *: * .** :: * *:***::**** *::: .** *: ** *:* **:.:::.* :*: * *: .*: ", "identical_positions": 116, "similar_positions": 80, "identity": "30.21%" }, { "cls_id": "homologset.agr.SGD:S000005233", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P7B2-1", "uniprot_id": "CNPD1_RAT", "id": "Q6P7B2-1", "name": "Protein CNPPD1", "aln": "MDLAGLLLDEEGTFSLSGFQDFTFLPGHQKLSARIRRRLYYGWDLETDCSLEELSSPVADITVELLQKAAPSPIRRLQKKYVAHVSREACISPCAMMLALVYIERLRHRNPDYLQHVSS--SDLFLISMMVASKYLYDEGEEEEVFNDEWG--AAGGVAVPTLNALERSFLSAMDWRLYTDPREIFEVLSWLESCVAEQQGRRRGWYTYTDLCVLLEQPMWQLSLGSLCQRLVKLSCLLAVAYVSSVALAVASMAVIHQSLGLSSSPSPSPPELTLVPKNLLQPCIPAPVPQCLT---NVSSCLEDSVELPSLWGSLLDPLTPPLMPPPDPPAPPTPFHKCPFCQKFQRNPPNCRACHQPNRTVSIGPIHPFYHTHGLAPPWLWSPVAPPFLQPQQCSLFSVMKLARLTSVIFPG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K158-1", "uniprot_id": "CNPD1_MOUSE", "id": "Q8K158-1", "name": "Protein CNPPD1", "aln": "MDLTGLLLDEEGAFSLTGFQDFMVLPGHQKLSARIRRRLYYGWDLETDCSLEELSSPVADITVELLQKAAPSPIRRLQKKYVAHVSREACISPCAMMLALVYIERLRHRNPDYLQHVSS--SDLFLISMMVASKYLYDEGEEEEVFNDEWG--AAGGVAVATLNALERSFLSAMDWRLYTDPREIFEVLSWLESCVAEQQGRRRGWYTYTDLCVLLEQPTWQLALGSLCQRLVKLSCLLAVAYVSSVALAVASVAVIHQSLGLSSSPSPGPPELTLVSKSLVQPCVPAPVSQCLT---NVSSCLEGSVDLPSLWGSLLAPLTPPLRPPPDPPAPPTPLHKCPLCQKFQRLPPNCRACHT-NQTVSIGPSRPLYHARGLAPPWLWSPVAPPFLQPQQCSLFSVMELAHLKSVISPG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BV87-1", "uniprot_id": "CNPD1_HUMAN", "id": "Q9BV87-1", "name": "Protein CNPPD1", "aln": "MDLTGLLLDEEGTFSLAGFQDFTFLPGHQKLSARIRRRLYYGWDWEADCSLEELSSPVADIAVELLQKAAPSPIRRLQKKYVAHVSREACISPCAMMLALVYIERLRHRNPDYLQHVSS--SDLFLISMMVASKYLYDEGEEEEVFNDEWG--AAGGVAVPTLNALERGFLSAMDWHLYTDPREIFEVLSWLESCVAEQQGRWRGWYTYTDLCVLLEQPTWQLALGSLCQRLVKLSCLLAVAYVSSVALAVASVAVIHQSLGLSCIPTPGPPDLGLTSRCLLEPCIPS-VPQCLPSLANVSSCLEGSMGLRSLWGSLLASLTPPPLPPPDPPAPPTLLHNCHLCQKLQRDSPTCHACLHPNRTVPTALSSPWYHTYGLAPPWPWSPVLLSLPQPQQCSLFSVMELARLKSFVFPG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P24867-1", "uniprot_id": "PCL1_YEAST", "id": "P24867-1", "name": "PHO85 cyclin-1", "aln": "---------------MCEYSKALHILLKSPVTDDIIK-------FLTDTTLRVVPSSNYPTPPGSPGEKHLTRLPSLMT-FITRLVRYTNVYTPTLLTAACYLNKLKRILPRDATGLPSTIHRIFLACLILSAKFHNDSSP----LNKHWARYTDGLFTLEDINLMERQLLQLLNWDLRVNTEDLILDLQPLLEPIKQDLARSSDQRKRINMMMSMNR---RTCAGTSPIRSNNRFKLYEKQRNVSIASDLSSATLVDS------------------------------------------------------------------------------------CNDLRR-----------LKDVTNIANNTVANTNYVRTVEKWN----DNVNRQSWDLEQIMSQHGF-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.. : :. :: * : :* :*. :.*. . : : : * . ::::: * : : . ::: * *:::*:: * :.* :** .:::::*: *.. :*..*. : * .:: :* :** :*. ::* * .:..::: *. * . : :: .* . . :: : ::: : . *: * : * *:* ::* :::.. *:.::* : *. . :: : . *. : *. .* .:*. : ", "identical_positions": 40, "similar_positions": 115, "identity": "9.64%" }, { "cls_id": "homologset.agr.SGD:S000005234", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DF29-1", "uniprot_id": "B5DF29_RAT", "id": "B5DF29-1", "name": "Activator 1 subunit 5", "aln": "MEIRLLVRCHCAPNARRATSYCIRDERPRVEKYRPQTLADLISHQDILSTIQKFISEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIVRGPILSFASTRTIFKRGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVQEENVDISEDGMKALVTLSSGDMRRALNILQSTNMAFG-----KVTEETVYTCTGHPLKTDIANILDWMLN-QDFTTAYKNIMELKTLKGLALHDILTEVHLFVHRVDFPSS-VRMHLLTKMADIEYRLSVGTSEKIQLSSLIAAFQVTRDLIVAEA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0F6-1", "uniprot_id": "RFC5_MOUSE", "id": "Q9D0F6-1", "name": "Replication factor C subunit 5", "aln": "-------MTAAAPSQQRPAAARARN-LPWVEKYRPQTLADLISHQDILSTIQKFISEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIVRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVQEENVDISEDGMKALVTLSSGDMRRALNILQSTNMAFG-----KVTEETVYTCTGHPLKTDIANILDWMLN-QDFTTAYKNIMELKTLKGLALHDILTEVHLFVHRVDFPSS-VRIHLLTKMADIEYRLSVGTSEKIQLSSLIAAFQVTRDLIVAEA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40937-1", "uniprot_id": "RFC5_HUMAN", "id": "P40937-1", "name": "Replication factor C subunit 5", "aln": "------METSALKQQEQPAATKIRN-LPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFG-----KVTEETVYTCTGHPLKSDIANILDWMLN-QDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSS-VRIHLLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKW3-1", "uniprot_id": "Q9VKW3_DROME", "id": "Q9VKW3-1", "name": "Activator 1 subunit 5", "aln": "------MSETSGPAVR----------MPWVEKYRPSGLDDLISHEEIISTITRFISRKQLPHLLFYGPPGTGKTSTILACARQLYSPQQFKSMVLELNASDDRGIGIVRGQILNFASTRTIFCDTFKLIILDEADAMTNDAQNALRRIIEKYTDNVRFCVICNYLSKIIPALQSRCTRFRFAPLSQDQMMPRLEKIIEAEAVQITEDGKRALLTLAKGDMRKVLNVLQSTVMAFD-----TVNEDNVYMCVGYPLRQDIEQILKALLSGSSLEDSFKTVESAKYARGLALEDIITELHLFVMRLELPMS-VMNKLIVKLAQIEERLAKGCTEVAQTAALVAAFFICRDMVSMEK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38629-1", "uniprot_id": "RFC3_YEAST", "id": "P38629-1", "name": "Replication factor C subunit 3", "aln": "------MSTSTEKRSKEN--------LPWVEKYRPETLDEVYGQNEVITTVRKFVDEGKLPHLLFYGPPGTGKTSTIVALAREIYG-KNYSNMVLELNASDDRGIDVVRNQIKDFASTRQIFSKGFKLIILDEADAMTNAAQNALRRVIERYTKNTRFCVLANYAHKLTPALLSRCTRFRFQPLPQEAIERRIANVLVHEKLKLSPNAEKALIELSNGDMRRVLNVLQSCKATLDNPDEDEISDDVIYECCGAPRPSDLKAVLKSILE-DDWGTAHYTLNKVRSAKGLALIDLIEGIVKILEDYELQNEETRVHLLTKLADIEYSISKGGNDQIQGSAVIGAIKASFENETVKANV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * ******. * :: .::::::*: :*:.. :*****:************:* *:::* ::: .*************.::*. * .***** ** ***:*********: *******:**::*.*.***::.** *: *** ******** **. : : *: ::: * :.:: :. :**: *:.****:.**:*** ::. :.:: :* * * * *: :*. :*. .. :. .: . : :**** *:: : :: :: . . :*:.*:*:** :: * .: * ::::.*: : : ", "identical_positions": 128, "similar_positions": 110, "identity": "35.96%" }, { "cls_id": "homologset.agr.SGD:S000005236", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M934-1", "uniprot_id": "TRUB1_RAT", "id": "Q5M934-1", "name": "Pseudouridylate synthase TRUB1", "aln": "MAAEEAEVVSP--LIVDTAP--DTSGTAAASLA-----AAVSAAAAAARTGSQAQVSKAALAAKLMSLSGVFAVHKPKGPTSAELLNRLKEKLLAEAGLPSPEWNKRQKQTLKVGHGGTLDSAAQGVLVVGIGRGTKMLTSMLSG-SKRYIATGELGKATDTLDSTGKVTEEKPYDKITQEDIEGILQKFTGNIMQVPPLYSALKKDGQRLSTLMKRGE-TVEARPARPVTVHSISLL--------------------------------------------------------------------------KYQPPFFTLDVECGGGFYIRSLVSDIGKELSSCATVLELTRTKQGPFTLAQHALPE--------------------DRWTINDIAQSLKRCTSLLPEELTFKKSKSEPSSDQALSCGYITLRETKREDDTVKTL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C0D0-1", "uniprot_id": "TRUB1_MOUSE", "id": "Q8C0D0-1", "name": "Pseudouridylate synthase TRUB1", "aln": "MAAAEAEVVSP--LIVDTAP--DTSGTAEASVA-----ASV---AEAARTESQAPASKAALAAKLMSLSGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSPEWNKRQKQTLKVGHGGTLDSAAQGVLVVGIGRGTKMLTSMLSG-SKRYITIGELGKATDTLDSTGKVTEEKPYDKITREDIEGILQKFTGNIMQVPPLYSALKKDGQRLSTLMKKGK-VVEARPARPVTVHSISLL--------------------------------------------------------------------------KFQPPFFTLDVECGGGFYIRSLVSDIGKELSSCASVLELTRTKQGPFTLAQHALPE--------------------DRWTIDDIEQSLERCTSLLPEELTFKKLKSDNSSDQVISCGYITLRDTKREDDAVKTL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWH5-1", "uniprot_id": "TRUB1_HUMAN", "id": "Q8WWH5-1", "name": "Pseudouridylate synthase TRUB1", "aln": "MAASEAAVVSSPSLKTDTSPVLETAGTVAAMAATPSARAAAAVVAAAARTGSEARVSKAALATKLLSLSGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSPEWTKRKKQTLKIGHGGTLDSAARGVLVVGIGSGTKMLTSMLSG-SKRYTAIGELGKATDTLDSTGRVTEEKPYDKITQEDIEGILQKFTGNIMQVPPLYSALKKDGQRLSTLMKRGE-VVEAKPARPVTVYSISLQ--------------------------------------------------------------------------KFQPPFFTLDVECGGGFYIRSLVSDIGKELSSCANVLELTRTKQGPFTLEEHALPE--------------------DKWTIDDIAQSLEHCSSLFPAELALKKSKPE-SNEQVLSCEYITLNEPKREDDVIKTC---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48567-1", "uniprot_id": "PUS4_YEAST", "id": "P48567-1", "name": "tRNA pseudouridine synthase 4", "aln": "----------------------------------------------MNGIFAIEKPSGITSNQFMLKLQHALTKSQVFSKEIQRATAERKQQYEKQTGKKASKRKLRKVSKVKMGHGGTLDPLASGVLVIGIGAGTKKLANYLSGTVKVYESEALFGVSTTSGDVEGEILSQNSVKHLNFDDLKTVEEKFVGQLKQTPPIYAALKMDGKPLHEYAREGKPLPRAIEPRQVTIYDLKVFSDSLKRDHDYPLLRPTTEEAVDTVKNLNANMLNDVLYFSKEYTEKHGLDSEVAKVEEPFPLSEQEEQEIQKEGDSYRAPKLHFKANVSSGTYIRSLVSDIGKSMRSSCYMVKLIRLQQQDWSLEKNNVFQLTDFTERDEKVWSKVLEKVLDEGATVDVIEELKKAEKEIPADVKECIVSSDQPGDEATAETIETANAEEHSNTLKRKIEQV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : ::.*. .:: : . . . *:: ::* :.: . *: ..:*:*******. * ****:*** *** *:. *** * * : . :* :* : * *.: .::. .::. :*:: : :**.*:: *.**:*:*** **: * :.*: .* .* **::.:.: .::.* : :..: ..* ***********.: *.. :::* * :* ::* :: : : *. : *: :.*::. . :* :: ..: ..::. : * . ::.: :. ", "identical_positions": 76, "similar_positions": 121, "identity": "16.93%" }, { "cls_id": "homologset.agr.SGD:S000005237", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D3N8-1", "uniprot_id": "GRTP1_MOUSE", "id": "Q9D3N8-1", "name": "Growth hormone-regulated TBC protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDPAERA-------------QAARARVPRIDPYGFER-PEDFDYAAYEEFFSTYLVILTKRAIKWSKLLKGNGGVRK----------SVTVKRYVRKGIPLEHRARVWMAVSGAQARMDQSPGYYHRLLEGE----------SSSSLDEAIRTDLNRTFPDNVMFRKTADPCL----QKTLYNVLLAYGLHNPDVGYCQCCAQKPGSSAGLRSSLTGMNFIAGYLILITKNEEESFWLLDALVGRILPDYYSPAMLGLKTDQEVLAELVRMKLPAVAALMDG------------------------------HGVLWTLLVSRWFICLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLIKQHQEFILEAS--------SIPDICDKFKQ-ITKGDFVTECHAFMQKIFSEPGSLSMTTITRLRKSCRAALQAQS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4QQU7-1", "uniprot_id": "GRTP1_RAT", "id": "Q4QQU7-1", "name": "Growth hormone-regulated TBC protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDPAERA-------------QAARARVPRIDPYGFER-PEDFDYAAYEEFFSTYLVILTKRAIKWSKLLKGSGGVRK----------SVT---------------------------------------------------------------DLNRTFPDNVMFRKTADPCL----QKTLYNVLLAYGLHNQDVGYCQ-----------------GMNFIAGYLILITKNEEESFWLLDALVGRILPDYYSPAMLGLKTDQEVLAELVRMKLPAVAALMDG------------------------------HGVLWTLLVSRWFICLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLIKQHQEFILEAS--------SVPDICDKFKQ-ITKGDFVTECHTFMQKIFSEPGSLSMATITRLRESCRAALQAQS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5TC63-1", "uniprot_id": "GRTP1_HUMAN", "id": "Q5TC63-1", "name": "Growth hormone-regulated TBC protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQPAE------------------RSRVPRIDPYGFER-PEDFDDAAYEKFFSSYLVTLTRRAIKWSRLLQG-GGVPR----------SRTVKRYVRKGVPLEHRARVWMVLSGAQAQMDQNPGYYHQLLQGE----------RNPRLEDAIRTDLNRTFPDNVKFRKTTDPCL----QRTLYNVLLAYGHHNQGVGYCQ-----------------GMNFIAGYLILITNNEEESFWLLDALVGRILPDYYSPAMLGLKTDQEVLGELVRAKLPAVGALMER------------------------------LGVLWTLLVSRWFICLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLIKQHQELILEAT--------SVPDICDKFKQ-ITKGSFVMECHTFMQKIFSEPGSLSMATVAKLRESCRARLLAQG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PBU5-1", "uniprot_id": "GRT1A_DANRE", "id": "Q6PBU5-1", "name": "Growth hormone-regulated TBC protein 1-A", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEERDRTGRTGQPQHRINQPSTARERANSVDAYGFQR-SDDFDYETHEQLMSEYLAVLTRRSIRWAKLLQGRRRVDR----------NLKVKRYVRKGVPNEHRPLVWMVCSGAQEQMDRNPGYYQSLLDTH----------HEPKLEESIRTDLHRTFPDNIYFRKSAEPCL----QQALYNVLVAYGHHNKAVGYCQ-----------------GMNFIAGYLILVSKDEETSFWLMEALLSRILPDYYTPAMLGLKTDQEVLGELVRLKAPAVWKLMQD------------------------------QGVMWTLVVSRWFICLFIDVLPVETVLRIWDCLFYEGSKILFRVALTLIRHHQQEIAEAQ--------NLPDVCERFKR-ITRGAFVEDCHTFMQKIFQEPGSLSMATVSKLRESCRARIIADES----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEY4-1", "uniprot_id": "Q9VEY4_DROME", "id": "Q9VEY4-1", "name": "Growth hormone-regulated TBC protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDATASS------------------KFSDVDEYGFKR-GDHFDYNNYSKFMDGYLKTLTRRRMKWEAILQQNTDLTQV---------DAKLKRYIRKGIPGPYRPDVWMKISGAAAAQRRSPDLFRNLLRTEP---------FDKEISDSISIDLPRTFPDNIHFDMK---------KQRLYNILIAYAHHNRDVGYCQ-----------------GLNYIAGLLLIVTDDEEKSFWLLKHIVENIVPQYHSHNMANLLRDLAVFRELVIRRIPAVNRHVDN------------------------------LGLPYPVIASKWFICIFAEVLPVETVLRIWDCVFAEGYKIVFRAALTMFVTHKNAILGCD--------DIAALANLFRDTMIQDNIVTDCHGFVEAMFSLR--LKRSELESLRK---VAVLNPA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P58802-1", "uniprot_id": "TB10A_MOUSE", "id": "P58802-1", "name": "TBC1 domain family member 10A", "aln": "---------------------------------------------------------------------------------------------------------------------------MAKSSRENGPREP-------------------------------AAGGS------------------------------------------------------------------LSGTR------------ESLAQGPDAATADELSSLGSDSEANG-FAERRIDKFGFIV-GSQGAEGALEEVP---LEVLRQRESKWLDMLNNWDKWMAKK--------HKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELDMSP----------GDPKWLDVIERDLHRQFPFHEMFVSRGGHG-----QQDLFRVLKAYTLYRPEEGYCQ------------------AQAPIAAVLLMHMPAEQAFWCLVQVCEKYLPGYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSR------------------------------QKIDPLLYMTEWFMCAFARTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLKHALGSPEKLK--------ACQGQYETIEQLRSLSPKIMQEAFLVQEVIELPVTERQIEREHLIQLRRWQETRGELECRSLPRMHGAKAILDAEPGPRPALQPSPSIR-LP----------------------------PDAALLSSKAKP---------------------HKQAQKEQK-RTKTSAQLDKSPGLSQATVVTAAGDACPPQGVSPKDPVPQDPTPQN------------LACHHSQESLTSQESEDTYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZSY8-1", "uniprot_id": "D3ZSY8_RAT", "id": "D3ZSY8-1", "name": "", "aln": "METGPAPLVAPPRRHGASAAPSPPPRGSRAGSVLVVAPGPPVTTATSAPVDLVVPGEARPAWVPGSLQTSASTPTTATGSTVELTLEASPEAAKTQEFPAPAAEAGAETSVALVLGTDTPKTEEARASPVPGPGTPTRTPSRTASGALTAKPPLAPKPGTTVASGVTARGGAGQVAGGHGAATSASAGPVPEDPSGPVTGPPGTCEASAPVARVTVTPAPETTENFQDLGSTSSLGPGISGPRGQAPDTLSYLDSVSLMSGTLESLTDDVSSVGSDSEING-LALRKTDKYGFLG-GSQYSGSLESSIP---VDVARQRELKWLEMFSNWDKWLSRR--------FQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEELERAP----------GDPKWLDVIEKDLHRQFPFHEMFAARGGHG-----QQDLYRILKAYTIYRPDEGYCQ------------------AQAPVAAVLLMHMPAEQAFWCLVQICDKYLPGYYSAGLEAIQLDGEIFFALLRRASPLAHRHLRR------------------------------QRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSVEKLR--------SCQGMYETMEQLRNLPQQCMQEDFLVHEVTTLPVTEALIERENAAQLKKWRETRGELQYRPSRRLHGSRAIHEERRRQQPPLGPSSSLLSLPSLKSRGSRAVGGAPSPPPPVRRASAGPVPGAVVIAEGLHPSLPSPTGNSTPLGTSKEIRRQEKERQKQEKEREKERQRQEKEREKQEKERQKWEKEQEKEQQKQEKERQKLEKKGQGRKLSLRRKADGPPAPQDGGDRSAAEARQDAYF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C9V1-1", "uniprot_id": "TB10C_MOUSE", "id": "Q8C9V1-1", "name": "Carabin", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQALGEDLLSELQDDSSSLGSDSELSGPSPYRQADRYGFIG-GNS-GELRLCQPS---ADLIRQREMKWVEMTLHWEKTMSRR--------YKKVKIQCRKGIPSALRARCWPLLCGARMCQKNNPGTYQELAAAP----------GDPQWMETIGRDLHRQFPLHEMFVSPQGHG-----QQGLLQVLKAYTLYRPEQGYCQ------------------AQGPVAAVLLMHLPPEEAFWCLVQICEVYLPGYYGPHMEAVQLDAEVFMALLRRQLPRVYKHLQQ------------------------------VGVGPLLYLPEWFLCLFTRSLPFPTVLRIWDAFLSEGAKVLFRVGLTLMRLALGTVEQRT--------ACPGLLETLGALRAIPPTQLQEEVFMSQVHSVTLSERVLQQEIRIQLAQLSKSLPGPAPLPQARLPGAQAIFESQQLAGVRESTKPEIP---------------------------------RIVVQPPEEP---------------------------------KPPRRKPQTRGKTFHGLLIRARGP-PIEGPSRSQR-------------------------------GSASFLDTRF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48566-1", "uniprot_id": "GYP3_YEAST", "id": "P48566-1", "name": "GTPase-activating protein GYP3", "aln": "-------------------------------------------------------------------------------------------MQNDQQRFSLQNRTVLAHPYKRLGGAFTVKSPSVPNFHDKMHSDHSSSDSALVNGSFRANDHRSVEPSCLGQASPSEHDGNLSVIDLYGDEVESQRAEGEDDDD------------------------------------------NNGDNGNEDLEEVHSDDLDLVPDDDNRQRVELEGAASATSANSNGINNTHFDRYGFKKQNNYISEAEYDKWWVEYSQYCVRRKHKWQLLLEKSGLPVTDDSPSRFPSKSERLKRYVRKGIPAEWRGNAWWHFARGQEKLNKNKGVYSQLLRKMKQIKKQNPNEKQVQDLDIIERDLNRTFPDNIHFQSSLHNKEGPPIIKSLRRVLVAFSLYNPKIGYCQS-----------------MNFLAGLLLLFLD-EERAFWMLVIITSRYLPGVHNINLEGVNIDQGVLMLCVKEYIPEVWSYIKPSIDHHQKNNKTFSPSNKKVLFNMQKNEFLYRLPPITLCTASWFMSCFVGVVPIETTLRIWDCLFYEESHFLFKVSLAVLKLSEHDLSKIKPRNNSLNYSWGSNLNQRGGSMGQEDSDMEIFQVIQTFPKTLLNPNEIFEKIIFKRRFNLNRLDQDEIDRCRKFVAAQRLKFKTYGELLGNSTSEADLPIN----------------------------------------------------------------DNTDNKGIHITSDAVNEALSSEVYGFKKSLAGVHWNNSIKEKVKQMRKKKDKGD-------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * :** . . :* :* : ** * ** : * : * .:* *: :. **** : . :::. * :** : : :* : : : * :: : * . : : . **:. * :* :.**:** .: * :.:*:..*.:: : : .: . : ", "identical_positions": 35, "similar_positions": 57, "identity": "3.98%" }, { "cls_id": "homologset.agr.SGD:S000005241", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80TL7-1", "uniprot_id": "MON2_MOUSE", "id": "Q80TL7-1", "name": "Protein MON2 homolog", "aln": "----MSCTNSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSETAAGNIINMLWQLMENSLE-ELKLLQTVLVLLTTNTVVHDEALSKAIVLCFR--LHFT-KDNITNNTAAATVRQVVTVVFERMVAEDDRHRD-IEPPVPIQGNSNRRSVSTLRPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTS--SSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDSDK--PQWLRAVAVESIHRLCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPPTGN-PATANQAGNNNAGGPASAPANSGVVGVGGGVTLLPAFEYRGAWIPILTVTVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITTMIEGELGEVEAEGPSVTEGASS--QSSERRDEQAASDPMDQETVSRAVWEEMVSACWCGLLAALSLLLDAS-TDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNATTAATLSNKSYSIQGQ---SVMMISPSS----ESHQQVVAVGQPLAVQ------PQGTVMLTSKNIQCMRTLLNLAHCHGAVLG-TSWQLVLATLQHLVWILGLKPSSGGALKPG-RAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVN---------------------MHRIEILWRPLTGHLLEKVCQHPNSR--MREWGAEALTSLIRAGLTFS-----HEPPLPQNQRLQLLLLNPLKEMSN-----------------INHPDIRLKQLECVLQILQSQGDSLGPGWPLVLGVMG------------AIRNDQGES------------LIRTAFQCLQLVVTDFLPTMPCSCLQIVVDVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGETIEKELNKEEAAQQKQAEEKGVSLNRP----FHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHSTWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSRAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPVRDSEKPEPP-AVSVPVPVLLGNLSGPGLSRPFVRTDSIGEKLGRCGS-ETPVVT--DELEDLKLWWAAWNTWHRTGSESTEPPSS-VDELT-------------FIPSQPFLTALVQIFPALYQHIKAG--FSMADLQKLGVILHSAVSVPISSDASPFILP--SYTEAVLTSLQEAVLTALDVLQKAICVGPENMQIMYPAIFDQLLAFVEFSCKPPQYGQLETKHIANAKYNQIQLFAPAEWVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQNI-IKTLRVPLSLKYSCPSESTWKLAVASLLKVLSIGLPVARQHASSGKFDSMWPELASTLEDFLFTKSIP-PDNLSIQEFQRNESIDVEVVQLISAEILPYANLIPKAFVGQMMTMLNKGSIHSQPCSFTEAEIDIRLREEFSKMCFETLLQFSFSNKVTTPQ------------------EGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTQPENVDGNTWSQVIALYPTLVECITCSSSDVGSALKEALAPFKDFMQPPASR----------VQNGES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZCG3-1", "uniprot_id": "D3ZCG3_RAT", "id": "D3ZCG3-1", "name": "Protein MON2 homolog", "aln": "----MSCTNSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGCGTKEPKVTQLCLAAIQRLMSHEVVSEAAAGNIINMLWQLMENSLE-ELKLLQTVLVLLTTNTVVHDEALSKAIVLCFR--LHFT-KDNITNNTAAATVRQVVTVVFERMVAEDDRHRD-IDPPVLIQGNSNRRSVSTLRPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSGTS--SSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDADK--PQWLRAVAVESIHRLCVQPRLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPPTGN-PAAANQAGNNNAGGPASAPANSGVVGIGAGVTLLPAFEYRGAWIPILTITVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITTMIEGELGEVETECPTVTEGASS--QSSERRDEQSESDHMDQETVSRAVWEEMVSACWCGLLAALSLLLDAS-TDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNATTAATLSNKSYSIQGQ---SVMMISPSS----ESHQQVVAVGQPLAVQ------PQGTVMLTSKNIQCMRTLLNLAHCHGAVLG-TSWQLVLATLQHLVWILGLKPSSGGALKPG-RAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVN---------------------MHRIEILWRPLTGHLLEKVCQHPNSR--MREWGAEALTSLIKAGLTFN-----HEPPLSQNQRLQLLLLNPLKEMSN-----------------INHPDIRLKQLECVLQILQSQGDSLGPGWPLVLGVMG------------AIRNDQGES------------LIRTAFQCLQLVVTDFLPTMPCSCLQIVVDVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGETIEKELNKEEAAQQKQAEEKGVSLNRP----FHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHATWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSRAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPARDSEKPETP-VGTVPVPVLIGNISGQGLSRPFVRTDSIGEKLGRCSS-EPPVVT--DEAEDLKLWWAAWNTWHRTGSESTEPPST-FDELT-------------FIPSQPFLTALIQIFPALYQHIKAG--FSMADLQKLGVILHSAVSVPISSDASPFILP--SYTEAVLTSLQEAVLTALDVLQKAICVGPENMQIMYPAIFEQLLAFVEFSCKPPQYGQLETKHIANAKHNQIQLFAPAEWVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQSI-IKTLRVPLSLKYSCPSESTWKLAVASLLKVLSIGLPVARQHASSGKFDSMWPELASTLEDFLFTKSIP-PDNLSIQEFQRNESIDVEVVQLISAEILPYANLIPKAFVAQMMTMLNRGSIHSQPSSFTEAEIDIRLREEFSKMCFETLLQFSFSNKVTTPQ------------------EGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTQPENVDGNTWAQVIALYPTLVECITCSSSDVCSALKEALVPFKDFMQPPASK----------VQNGES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z3U7-1", "uniprot_id": "MON2_HUMAN", "id": "Q7Z3U7-1", "name": "Protein MON2 homolog", "aln": "----MSGTSSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSETAAGNIINMLWQLMENSLE-ELKLLQTVLVLLTTNTVVHDEALSKAIVLCFR--LHFT-KDNITNNTAAATVRQVVTVVFERMVAEDERHRDIIEQPVLVQGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTS--SSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDADK--PQWLRAVAVESIHRFCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPPTGN-PATSNQAGNNNLGGSVSAPANSGMVGIGGGVTLLPAFEYRGTWIPILTITVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITSMIEGELGELETECQTTTEEGSSPTQSTEQQDLQSTSDQMDKEIVSRAVWEEMVNACWCGLLAALSLLLDAS-TDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNTTTAATLSNKSYSVQGQ---SVMMISPSS----ESHQQVVAVGQPLAVQ------PQGTVMLTSKNIQCMRTLLNLAHCHGAVLG-TSWQLVLATLQHLVWILGLKPSSGGALKPG-RAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVN---------------------MHRIEILWRPLTGHLLE-VCQHPNSR--MREWGAEALTSLIKAGLTFN-----HDPPLSQNQRLQLLLLNPLKEMSN-----------------INHPDIRLKQLECVLQILQSQGDSLGPGWPLVLGVMG------------AIRNDQGES------------LIRTAFQCLQLVVTDFLPTMPCTCLQIVVDVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGETIEKELNKEEAAQQKQAEEKGVVLNRP----FHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHSTWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSRAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPVRDSDKPETPPVVNVPVPVLIGPISG--MSRPFVRTDSIGEKLGRYSSSEPPIVT--DELEDLNLWWAAWNTWYRIGSESTKPPIT-FDKLT-------------FIPSQPFLTALIQIFPALYQHIKTG--FNMDDLQKLGVILHSAISVPISSDASPFILP--SYTEAVLTSLQEAVLTALDVLQKAICVGPENMQIMYPAIFDQLLAFVEFSCKPPQYGQLETKHIANAKYNQIQLFAPAEWVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQNI-IKTLRVPLSLKYSCPSESTWKLAVSSLLRVLSIGLPVARQHASSGKFDSMWPELANTFEDFLFTKSIP-PDNLSIQEFQRNENIDVEVVQLISNEILPYANFIPKEFVGQIMTMLNKGSIHSQSSSFTEAEIDIRLREEFSKMCFETLLQFSFSNKVTTPQ------------------EGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTQPENVDGNTWAQVIALYPTLVECITCSSSEVCSALKEALVPFKDFMQPPASR----------VQNGES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P6K6-1", "uniprot_id": "A0A8M9P6K6_DANRE", "id": "A0A8M9P6K6-1", "name": "Protein MON2 homolog", "aln": "-MSLKMSTSSPEAVKKLLENMQADLRSLSMECKKKFPPVKEAAESGIVKIKTIAARNTDILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSEAAAGNIINMLWQLMENGLE-ELKLLQTVLVLLTTNTIVHDEVLSKAIVLCFR--LHFT-KDNITNNTAAATVRQVVTVVFERMVAEDERFKGLNEEPPAVQGNCNRRSVSTLRPSAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSSSS-ASPAPVEKPYFPICMRLLRVVSVLIKHFYSLLVTECEIFLSLLVKFLDGEK--PQWLRAVAVESVHRLCVQPHLLRSFCQSYDMKPHSTKVFRDIVNALGSFIQSLFILPSAGNTSSTSTPAGGSVSSSQASGPGGPGLTGAGGALTTQAAFEYRGTWIPLMNVSVQGSAKATYLEMLDKVEPPSIPEGYAMSVAFSALLDLVRGITNMIDRELLRQE--------------QQEAMREEEEPVSPPAQEPLAAEVWQEMVNACWCGLLAALSLLLDAS-TDETATENILKAELSMASLCGRLGLVTPRDAFITAVCKASLPPHYALTILSSS-ASSLTNKVYSIQGQ---SVQMVSPSS----ESHQQVVAVGQPLSAQ------PQGTVVLTAKNIQCMRTLLNLAHCHGAHLG-TSWQLVLATLQHLVWILGLKPAPGGVLKPG-RAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSMEAMEMAYGTNKEPSLFAVAKLLETGLVN---------------------MDRIEILWRPLTAHLLE-VCQHPNAR--MREWGAEAITSLIKAGLSYK-----HDPPLSQNQRLQLLLLNPLKELSN-----------------VLHADIRQKQLECVLQILQNQGDSLGPGWPLVLGVIG------------AIRNDQGES------------LIRTAFQCLQLVVTDFLPTMPCMCLQIVVDVAGSFGLQNQELNISLTSIGLLWNISDYFFQRGEAITEELDKEEAVLLKQAQDKGEPLNRP----FHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTMFSTIAAHGTLLQPPTWNIVVWKVLFHLLDCVRKSSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQQLGDFFKAWEVLLDHIQSAALSKNNEVSLAALKSFQEILQLVTPIKDTDKPDALSAIDVPS-VLMESLQGSGPGRPLVRSDSLAERLAQRYAAQPSLPPPGEELDDSALWWSAWNTWYRVGTECTRPPSGGTDKLV-------------FVPSQPFLTALIQIFPALYQHIAGG--FSMEDLKKLGVILHGAVSVPISSDSSPFILP--SYTEAVLTSLQEAVLTALDVLQKAICVSSENLQVMYPAIFEQLLLFVEFSCKPPQYGKMETKHVANAKYNQIQLFAPAEWVALNYVPFAERSLEVVVDLYHKTACHKAVINEKVLQNI-IKTVRIPLGLKYACPAESTWKLAVSSLLKVLSIGLPVARQQASSGKFDTMWPELANAFEDFLFTKSTP-PDNLSIQEFQRNEAVDVEVVQLISSEILPFANFIPKEFVGRIMSMLNKGSIHSQSSSFTEAEMDMRMREDFSKVCFETLLQFSFSNKVSTPQ------------------EGFISRMALSVLLQRAQDVLRRYVEDERLSGRCPLPRQQVTEIIFVLKAISTLMDSLKKTQPENVDGNVWAQVIALYPTLVECITCTSPEVSSALKDALGPFKDFMQPPVSK----------VQNGES", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLT1-1", "uniprot_id": "MON2_DROME", "id": "Q9VLT1-1", "name": "Protein MON2 homolog", "aln": "MSFVGGGGCGGQDVHKFVEALQADFKTLSLETKKKYPQIKEACEEAISKLCTAGSSQ---QNSVYYTVNQILYPLVQGCETKDLKIIKFCLGMMQRLITQQVVDQKGALYITNALWTLMENNIE-EVKVLQTVTLLLTTNTVVHGDTLAKALVLCFR--LHYA-KNPTIVNTAGATIRQLVSLVFERVYLEKDSVSSLQQQQSSGSPAEGEGGNQDVQTFASDAFLLFQDLVQLVNADQPYWLLGMTEMTRTFGLELLEAVLTNFSAVFHESNDFRLLLKERVCALVIKLFSPNVKHRQLPAPSNGNAPVPAEKPYFPISMRLLRLVAILIQKYHTILVTECEIFLSLIIKFLDPDK--PAWQRALALEVIHKLVTRSSLIAFFCKSYDLKNHATNIVHDMIAAMGSYIRYSLIN--------ASAMLNGQQNGVANSLTAMSGSNQCG--------FMFRGAYLPLVATYAPGVSKAVYLEMLDKIDASNIPDSYGISVGHAILLDMTRSIGGVIQRTP-----------------------ELHPSHNTAVITEEEHKPLCLQLVNSSWSALLSAFIPLVETS-IDEATTENILKAMQNYAALCGMLEQLQPRDAFIMAMCRASFPPHYAMSIFANTTQSDGDLRCHTRSGSQDLSSQFINSCSGDAGDFRPQIVAVGTPLPSASLPHSVMQAPVMLTNKNLQCMRAILFLAHNNGGILG-TSWHIVLQTLQHLVWILGLKPSTGGSLQAMPKPAVEANVGIQTAVMADLPVLSQMLSQLFESSQYLDDVALHHLIDALCKLSHEAMELAYAN-REPSLFAVAKLLETGLVN---------------------MPRIKVLWRPLTNHLLE-VCQHRHIR--MREWGVEAITYLVKSALQFK-----HKTPLKENMELQTMLLSPLSELST-----------------VLHADVRQRQLDCVLQILNTAGEILSFGWPAIIEIIG------------AVNEHHGEP------------LIRTAFQCLQLVITDFLTVMPWRCLPLCISTAAKFGSQTQELNISLTAIGLMWNISDFFNQ----------NQDKLMSTQLQDVSILPDFPG---TVKMPQFDKLWMCLYAKLGELCVDLRPAVRKSAGQTLFSTISAHGSLLNPPTWQALVWQVLFPLLDNVRALSSSASNEKVDASG-NILIHHSRNTAQKQWAETQVLTLSGVCRVFNTKRELLQMLGDFERAWSLILEFIQNAALSKNGEVSLAALKSLQEIMYHNTAER--------------------------TERALKDPQTAQE-------------------QDEEIWTIAWNIWLSIGMESTKMSTSTSAKLQQQNSNGAETQEDFYIPSQAFLTALIQIFPAIFQHIQVK--FTAADFDKFCTVLTNAVCIPVQTDAVPYIMS--TVSDTLLTPLHDGILDCMELIQKEATKPDSHISQLIPAIFRQLLIFSKFACAPPTFQQSVEHKYAKSSG-HYANNASVEVVSMNYIPFGEKSISICVKLYQTTATEDSVVQEQILHDI-VKALRTPLAMKYKCLSSSTWKLAISSLISVLHTGLKVAR--AKPQHFASLWDDLADTLDKFLFPASVCTIEDRGLEEIVLDETIDCQVIELLRDEVLPHSHEMPHQFIMQIVVLLNKGSIHSASDTNICYESDWKLREIFAKTCFETLLQFSLLEDHANTNNNRLNANVLTAGAAGAGGKDFAGRLAVTALLHRFQEVLKRFNDDERQSGKCPLPRFRLSEISFVLKAIATLVVSMKKAPASKVNKPAWDQLIGLYPYLVDCTTTTSPEVSRSLREALLQYTDLLQAPRSCSAATSNDNVIQSNGQE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48563-1", "uniprot_id": "MON2_YEAST", "id": "P48563-1", "name": "Protein MON2", "aln": "------MAMNTGGFDSMQRQLEAELRSLSSESKRRNSTIRHASDKSIEILKRVHSFE------ELERHPDFALPFVLACQSRNAKMTTLAMQCLQGLSTVPSIPRSRLSEILDAFIEATHLAMEIQLKVLQVVPIFFKTYGKFIYGPLCKKLLLCCSNLLHVPNKAPVVVGTASATLQQLIDEIFDRLSIESVVDDKQYEVLISNSESIKVNVYRYDANKLFDNICSLNEISSNGAVSDEEMLLDIGDIPIDYGLEILESILKNSQKNLLECQDLQYLLRVKAIPLLLRCISSSRHFSTAVRSCR--------------CLKLL-----IRKEYLSILELELEVILSLLIHGISVESNLSGWQRVLSLELFKDLSQDPEIVNTLYMDYDNYPDKKHVFKYLLKECIVLLNS----------PEYITFLAPSKVVEKMDSP---------------------------LITTENSTVKTKFMHLLDKSNAPSINITYIISLILTICNHLCEGLNKSALESS----------------------PLEKKIEDKEREEGTGNDSTVVKVYSGLFSGLFELNKLFLYSTSLETSIFHLVVRAFQKLAHSAGVLSLKDKLRACMKLFSILITNNVTSSNQYSFNDTSKSAKNQHTRNIS---TSSVTTSPVESTKNPSRSIADSAQNKEMKR-----RLHPRNISSRQVSLLRALISLSISLGPIFDSESWRYTFLTWQWITYYIYGPSADFKESFYSEDIPPPPILTKSDVTSIESSLTKFFESTSSYSCSTFHLVLTRLILDSKNTLTLEQTNLNLNNDIGYHPLDAKDEIIPCIYNKAFFVNKIGELATYNCKKFLFGKNGKELWSLISTYMIKLISNREMDNDSLRLYTVRVFTDIIKKATNEVGNSDEQDNKVKQFGTLENLVIDSLMATINSIKQLDIGKQEIYNGTINVESDILFQLLLTLKEILNEFGELLMNSWTNIFNIINSPFEWTVEDTDFSVNEDIDDSSLFEGIVQKHKNMIQVSYDVFKLISDDFLQSLPMSVIKFVIDTLVNFVSQKRNLNISFSSISQFWLVGDYLRVRFNPETLNLSDEKRRSLSEKINNQKLIEIITSSSSHDWELYNGLWIYLLKNLINCTNDDRVEVKNGAVQTFFRIIDSHSVCFPP--WDLIFLEVIEPLLTKEWSTEELENET-----------------------DFINVTLQGLIKLYPEHFKDFKNNTTCAKEWSMLLDFLKRLLSSTSNNTKNAVILNYQTLLKEIITIED---------------------------------------------------------VPSDILKKCCEIFTDYNITYSDLSTNASSKTEY-----------------DCIYELITGFPPLYQLISKYDAMTDEFVEKVLLLFNSAIKYPLLPEFVQDKTKPSSMQKAILSGLDIFMTNDSKDTEILILLQLSTISILAFDTREKITKKLGPKLPKASLNRLPTFEAISYMSCSNLRNRIAKIDQFGISTLKAKHILRILKNLAEIIKRKSLITGSESDEIPIWVLASNCFCDLSNKIFKSLQEDAENPLKDNFCDLFINVIVVTLQRINPELDNLTEIDDLNEYSKYREILLENRIIDLFNERQLDTFIYAVWDCSFLYEFDELENALMQDCGTFSELSQKLSSFDFSCIFGSTTNPRFQTKYKCSLECLQDLVNFMLNTNEK--------------------LRKLTAPYLSARIALALRRYISDEYLIGRAPIPKLRKTELATLLNGLCVILRGVLDQNSTLGNKQIGVENLQTLSPLILRTIPVSHKMDGLQDKVLELSLGFTKLD-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ...: . :::::::** * *:: . ::.*.:..* : : : :. *:: .* ::: *: :.: :* * : : . * : : . :* ::*:**.* :::.* . *.* ::** ** . * .**.**::*:: :*:*: *. : . * :::: . .. *:.: ::. :***:**::*.: : : ::: **: :. .*::: :*.. :. .. .::** : :.: ::* * *::***::: :. :. . * *.:::* .: : . :: : .** . .::.: :: :. . . . : . *: ::.:*** :...* * :*: .: ..: :: .. :..*: :: :: : : . :::* . * .* * * : .. : . . : . :: . . : . .. : .:. . . :: :::. :*::: *: * :. **: .: * * :.: : .: . .. : .: . : * *.. :. * : :::: .*: * :: . : . . : . : * . : ** :: :::: :.:: . :* : ...:* ::: . :. : : *: :::..* . ..*: : * : :**: *: * .*. :: ::. ::.:. .:. :*:.::: ::*: *** :* : : :.. .* :.::****:::*. :* :.*:: .:. .: : : :: **: * :* : * * *::.* **:* * :*. : *. :. :*: ** . .: : :** *: ::: : :: : *.::*:.:: *...:.. *.: . * :: . . : . : : . : . : : *: **.::* * :. ..*. :: .*: *: .: : .::*: *. : . : . :. : :: . : . . .: :. .: : : :. ..::: . ..* : .: . .: : . : .* : .. :: . :*:. : :. : : :: :. :* : : ..* . : : :: : : .. * . * * ** . . : ::: . * * .*:*: .** *:.*:*: : :*: :*:.:..:: .: . . : : : . *: * .: ..* .: : ", "identical_positions": 170, "similar_positions": 553, "identity": "9.08%" }, { "cls_id": "homologset.agr.SGD:S000005242", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88643-1", "uniprot_id": "PAK1_MOUSE", "id": "O88643-1", "name": "Serine/threonine-protein kinase PAK 1", "aln": "--------------MSNNGVDIQDKPPAPPMRNTSTM-------------------------IGAGSKDTGTLNHGSK-----------------------------------PLPPNPEEKKKKDRF----------YRSILPG--DKTNKKREKERPE----------------------------ISLPSDFEHTIHVGFDAVTGEFT---------------GMPEQWARLLQTSNITKSEQ---------KKNPQAVLDVLEFYNSKKT----------------SNSKKYMSFT--DKSAEDYN---------SSNTLNVKTVSET--------------------------------------------------------------------------PAVPPVSEDDEDDDDD---------ATPPPVIAP------RPEH-TKSVYTR------SVIEPLP-VTPTR------------DVATSPIS------------PTEN----------------------NTTPPDALTRN-----------------TEKQKKKPKMSDEEILEKL--------RSIVSVGDPKKKYTPFEKIGQGASGTVYTAM-------------------DVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVG-DELWVVMEYLAGGSLTDVVTETCMD--------EGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLQCCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLMHAAKEATKNNH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35465-1", "uniprot_id": "PAK1_RAT", "id": "P35465-1", "name": "Serine/threonine-protein kinase PAK 1", "aln": "--------------MSNNGLDVQDKPPAPPMRNTSTM-------------------------IGAGSKDPGTLNHGSK-----------------------------------PLPPNPEEKKKKDRF----------YRSILAG--DKTNKKKEKERPE----------------------------ISLPSDFEHTIHVGFDAVTGEFT---------------GMPEQWARLLQTSNITKSEQ---------KKNPQAVLDVLEFYNSKKT----------------SNSQKYMSFT--DKSAEDYN---------SSNTLNVKTVSET--------------------------------------------------------------------------PAVPPVSED-EDDDDD---------ATPPPVIAP------RPEH-TKSVYTR------SVIEPLP-VTPTR------------DVATSPIS------------PTEN----------------------NTTPPDALTRN-----------------TEKQKKKPKMSDEEILEKL--------RSIVSVGDPKKKYTRFEKIGQGASGTVYTAM-------------------DVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVG-DELWVVMEYLAGGSLTDVVTETCMD--------EGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEATKNNH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13153-1", "uniprot_id": "PAK1_HUMAN", "id": "Q13153-1", "name": "Serine/threonine-protein kinase PAK 1", "aln": "--------------MSNNGLDIQDKPPAPPMRNTSTM-------------------------IGAGSKDAGTLNHGSK-----------------------------------PLPPNPEEKKKKDRF----------YRSILPG--DKTNKKKEKERPE----------------------------ISLPSDFEHTIHVGFDAVTGEFT---------------GMPEQWARLLQTSNITKSEQ---------KKNPQAVLDVLEFYNSKKT----------------SNSQKYMSFT--DKSAEDYN---------SSNALNVKAVSET--------------------------------------------------------------------------PAVPPVSEDEDDDDDD---------ATPPPVIAP------RPEH-TKSVYTR------SVIEPLP-VTPTR------------DVATSPIS------------PTEN----------------------NTTPPDALTRN-----------------TEKQKKKPKMSDEEILEKL--------RSIVSVGDPKKKYTRFEKIGQGASGTVYTAM-------------------DVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVG-DELWVVMEYLAGGSLTDVVTETCMD--------EGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEATKNNH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P9X9-1", "uniprot_id": "A0A8M9P9X9_DANRE", "id": "A0A8M9P9X9-1", "name": "non-specific serine/threonine protein kinase", "aln": "--------------MSDNG-EVEDKPPAPPMRNTSTM-------------------------IGSSGKDSGPLNHGSK-----------------------------------PLPPNPEDKRRKEGF----------IRSILTG--GGDKTNKKKERPE----------------------------ISLPSDFEHTIHVGFDAVTGEFT---------------GMPEQWARLLQTSNITKLEQ---------KKNPQAVLDVLKFYDSKET----------------SNNQKYMSFT--DKGVENFN---------SSSAVVPKTVSET--------------------------------------------------------------------------PAVATVSEDEDEEEDE---------ATPPPVIAP------RPEH-TKSIYTR------SVIEPLPPPLSTK------------DAATSPITNAAADGGSSSNAPSSNTNTTNTNTTNTTN-------TTNTTSTSAASSTNAPS----------TPQTTDKSRKKKMSDEEILEKLNVLRSPSAGSIVSVGDPKKKYTRFEKIGQGASGTVYTAI-------------------DIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVG-DELWVVMEYLAGGSLTDVVTETCMD--------EAQIAAVCRECLQALEFLHCNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAVFRDFLNRCLEMDVEKRGSAKELLQHQFLKVAKPLSSLTPLIIAAKEAAKNNR-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q61036-1", "uniprot_id": "PAK3_MOUSE", "id": "Q61036-1", "name": "Serine/threonine-protein kinase PAK 3", "aln": "---------------MSDSLDNEEKPPAPPLR------------------------------MNSNNRDSSALNHSSK-----------------------------------PLPMAPEEKNKKAR-----------LRSIFPGGGDKTNKKKEKERPE----------------------------ISLPSDFEHTIHVGFDAVTGEFTPDLYGSQMCPGKLPEGIPEQWARLLQTSNITKLEQ---------KKNPQAVLDVLKFYDSKET----------------VNNQKYMSFTSGDKSAHGYI---------AAHQSNTKTASEP--------------------------------------------------------------------------PLAPPVSEEEDEEEEEEE-----DDNEPPPVIAP------RPEH-TKSIYTR------SVVESIASPAAPN------------KEDIPPSAEN--------------------------------------ANSTTLYRN-----------------TDRQRKKSKMTDEEILEKL--------RSIVSVGDPKKKYTRFEKIGQGASGTVYTAL-------------------DIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVG-DELWVVMEYLAGGSLTDVVTETCMD--------EGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIKNSSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62829-1", "uniprot_id": "PAK3_RAT", "id": "Q62829-1", "name": "Serine/threonine-protein kinase PAK 3", "aln": "---------------MSDSLDNEEKPPAPPLR------------------------------MNSNNRDSSALNHSSK-----------------------------------PLPMAPEEKNKKAR-----------LRSIFPGGGDKTNKKKEKERPE----------------------------ISLPSDFEHTIHVGFDAVTGEFT---------------GIPEQWARLLQTSNITKLEQ---------KKNPQAVLDVLKFYDSKET----------------VNNQKYMSFTSGDKSAHGYI---------AAHQSNTKTASEP--------------------------------------------------------------------------PLAPPVSEEEDEEEEEEE-----DDNEPPPVIAP------RPEH-TKSIYTR------SVVESIASPAAPN------------KEATPPSAEN--------------------------------------ANSSTLYRN-----------------TDRQRKKSKMTDEEILEKL--------RSIVSVGDPKKKYTRFEKIGQGASGTVYTAL-------------------DIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVG-DELWVVMEYLAGGSLTDVVTETCMD--------EGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLILAAKEAIKNSSR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75914-1", "uniprot_id": "PAK3_HUMAN", "id": "O75914-1", "name": "Serine/threonine-protein kinase PAK 3", "aln": "---------------MSDGLDNEEKPPAPPLR------------------------------MNSNNRDSSALNHSSK-----------------------------------PLPMAPEEKNKKAR-----------LRSIFPGGGDKTNKKKEKERPE----------------------------ISLPSDFEHTIHVGFDAVTGEFTPDLYGSQMCPGKLPEGIPEQWARLLQTSNITKLEQ---------KKNPQAVLDVLKFYDSKET----------------VNNQKYMSFTSGDKSAHGYI---------AAHPSSTKTASEP--------------------------------------------------------------------------PLAPPVSEEEDEEEEEEE-----DENEPPPVIAP------RPEH-TKSIYTR------SVVESIASPAVPN------------KEVTPPSAEN--------------------------------------ANSSTLYRN-----------------TDRQRKKSKMTDEEILEKL--------RSIVSVGDPKKKYTRFEKIGQGASGTVYTAL-------------------DIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVG-DELWVVMEYLAGGSLTDVVTETCMD--------EGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIKNSSR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CIN4-1", "uniprot_id": "PAK2_MOUSE", "id": "Q8CIN4-1", "name": "Serine/threonine-protein kinase PAK 2", "aln": "--------------MSDNG-ELEDKPPAPPVRMSSTI-------------------------FSTGGKDPLSANHSLK-----------------------------------PLPSVPEEKKPRNK-----------IISIFSG-TEKGSKKKEKERPE----------------------------ISPPSDFEHTIHVGFDAVTGEFT---------------GMPEQWARLLQTSNITKLEQ---------KKNPQAVLDVLKFYDSN------------------TVKQKYLSFT--PPEKDGFP---------SGTPALNTKGSET--------------------------------------------------------------------------SAV--VTEEDDDDEDA-----------APPVIAP------RPDH-TKSIYTR------SVIDPIPAPVGDS------------NVDSGAKS------------------------------------------------------------------SDKQKKKAKMTDEEIMEKL--------RTIVSIGDPKKKYTRYEKIGQGASGTVFTAT-------------------DVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVG-DELFVVMEYLAGGSLTDVVTETCMD--------EAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLILAAKEAMKSNR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64303-1", "uniprot_id": "PAK2_RAT", "id": "Q64303-1", "name": "Serine/threonine-protein kinase PAK 2", "aln": "--------------MSDNG-ELEDKPPAPPVRMSSTI-------------------------FSTGGKDPLSANHSLK-----------------------------------PLPSVPEEKKPRNK-----------IISIFSS-TEKGSKKKEKERPE----------------------------ISPPSDFEHTIHVGFDAVTGEFT---------------GMPEQWARLLQTSNITKLEQ---------KKNPQAVLDVLKFYDSN------------------TVKQKYLSFT--PPEKDGFP---------SGTPALNTKGSET--------------------------------------------------------------------------SAV--VTEEDDDDEDA-----------APPVIAP------RPDH-TKSIYTR------SVIDPIPAPVGDS------------NVDSGAKS------------------------------------------------------------------SDKQKKKAKMTDEEIMEKL--------RTIVSIGDPKKKYTRYEKIGQGASGTVFTAT-------------------DVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVG-DELFVVMEYLAGGSLTDVVTETCMD--------EAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLILAAKEAMKSNR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13177-1", "uniprot_id": "PAK2_HUMAN", "id": "Q13177-1", "name": "Serine/threonine-protein kinase PAK 2", "aln": "--------------MSDNG-ELEDKPPAPPVRMSSTI-------------------------FSTGGKDPLSANHSLK-----------------------------------PLPSVPEEKKPRHK-----------IISIFSG-TEKGSKKKEKERPE----------------------------ISPPSDFEHTIHVGFDAVTGEFT---------------GMPEQWARLLQTSNITKLEQ---------KKNPQAVLDVLKFYDSN------------------TVKQKYLSFT--PPEKDGFP---------SGTPALNAKGTEA--------------------------------------------------------------------------PAV--VTEEEDDDEET-----------APPVIAP------RPDH-TKSIYTR------SVIDPVPAPVGDS------------HVDGAAKS------------------------------------------------------------------LDKQKKKTKMTDEEIMEKL--------RTIVSIGDPKKKYTRYEKIGQGASGTVFTAT-------------------DVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVG-DELFVVMEYLAGGSLTDVVTETCMD--------EAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKEAMKSNR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VI13-1", "uniprot_id": "PAK_DROME", "id": "Q9VI13-1", "name": "Serine/threonine-protein kinase Pak", "aln": "--------------MSSEE----DKPPAPPVRLTSNRGGN-----------ERSGGGVGVGGGGLGGGGMGDVPPDMR-----------------------------------PLPKEPDDSDRKKKT----------LKSKIKG----SKPSHTDSKPN----------------------------ISYPTNFEHTVHVGFDAVTGEFT---------------GMPEAWARLLMNSNISKQEQ---------KKNPQAVLDVLKWFDNTTKQ---------------RPSSKYMTNAITTHSGSSLSRVS------SSSPSSTPTDSELHGSNSGGNLIGVQLGSMTLGPNANNVAVAGQILGNHYQQQQQHLLQQQQPLLHQNHNQHHMGISQSHSYNFVGHTVSSSTSQHSSANEDDMLGPQHPQQQPPPPPVAS------RPER-TKSIYTRPIEDLQPAIIPMPVAPATTPATPLQNHRTPGGISAPAASPMMHNNATTTLDKNKNNANLYTPEPTVAQ-------VSAGGPSSQVAGNQIAVPQAAVAPAATPNTRAANAKKKKMSDEEILEKL--------RTIVSVGDPNRKYTKMEKIGQGASGTVYTAI-------------------ESSTGMEVAIKQMNLSQQPKKELIINEILVMRENKHPNVVNYLDSYLVS-EELWVVMEYLPGGSLTDVVTETCMD--------EGQIAAVCREVLQALEFLHANQVIHRDIKSDNILLGLDGSVKLTDFGFCAQISPEQSKRTTMVGTPYWMAPEVVTRKQYGPKVDLWSLGIMAIEMVEGEPPYLNENPLKALYLIATNGKPEIKEKDKLSSAFQDFLDQCLEVEVDRRASALDLLKHPFLKLARPLASLTPLIMAAKEATKGN--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48562-1", "uniprot_id": "CLA4_YEAST", "id": "P48562-1", "name": "Serine/threonine-protein kinase CLA4", "aln": "-----MSLSAAANKISDNDFQNIGPAPRPPSSNSQGRTCYNQTQPITKLMSQLDLTSASHLGTSTSKKKSGWVSYKDDGILSFIWQKRYLMLHDSYVALYKNDKQNDDAILKIPLTSIISVSRTQLKQYCFELVRCSDRNSVSSGSSSSLNVSSDSNSKKSIYIATKTESDLHSWLDAIFAKCPLLSGVSSPTNFTHKVHVGFDPETGSFV---------------GMPTNWEKLLKHSRITGEDW---------NNNSAAVIQVLQFYQEYNGAGNPTNTLDKPQSGETSSSQKSLPNSYNDNKLRNNSVNSKSSSGVSSSMVSQRKTSQPPNTKSPVSLGSGSLPPINTKLPTSQSNIPRHLQNVPNQQYPKMRNG--------HSPTNGQFPRGPMHPNNSQRSLQQQQQQQQQQKQQHQQYPYHHQGPSPSPSPSPSPLNPYRPHHNMINPYSK------QPQSPLSSQSTQN------QAIPRYAQNSSPTAAHFQPQRTAPKPPISAPRAPYPSNQNATSNTHVQPVAPKNDQSTPQTMRQAPKRPDADVAQPGGVAKPKKPARPTMSTAEIMSKL--------KKVTVNADPSQCFKVIEKAGQGASGSVYLAERTHIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPRKELIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLKHPESLSLEIKRFLSVCLCVDVRYRASTEELLHHGFFNMACDPKDLTSLLEWKE--------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q3ULB5-1", "uniprot_id": "PAK6_MOUSE", "id": "Q3ULB5-1", "name": "Serine/threonine-protein kinase PAK 6", "aln": "MFR--KKKKKRPEISAPQNFQHRVHTSFDPKEGKFVG-----------------LPPQWQNILDTLRRPKPVVDPSRITRVQLQ-----------------------------PMKTVVRGSSVPTEGYISGLLNDIQKLSVISSNTLRGRSPTSRRRAQSLG------------------LLGDDQWAADPDMYLQSPQSEHTDPHGLYLSCNGGTPAGHRQVPWPEPQSPQALPNGMAAKAQSLGPAEFQGASQRCLQQLGACLQSSPPGTSPPMATGRRGVKVAKHSSEEARPQSCLVGSAIGRPGGEGSPSPKNQESSLKHRLFRSMFLSTPATG-------------------------------------------------------------AASSSKPVPLPQNKPNSAFRPPQKDSSSNLVAKAQSLPSE------QPMGTFSPLTTSDTSSPQKSLRTAPAAGPLP------------GRSSPAGSPRT---------------------------------RHAQISTSNLYLPQDPT---------VAKGALGGEDTGIVTHEQFKAAL--------RMVVDQGDPRLLLDSYVKIGEGSTGIVCLAR-------------------EKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHLNVVEMYKSYLVG-EELWVLMEFLQGGALTDIISQVRLN--------EEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSAPPKLKNSYKVSPVLRDFLDRMLVREPQERATAQELLDHPFLLQTGLPECLVPLIQLYRKQTSTC--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LCF1-1", "uniprot_id": "A0ABK0LCF1_RAT", "id": "A0ABK0LCF1-1", "name": "non-specific serine/threonine protein kinase", "aln": "MFR--KKKKKRPEISAPQNFQHRVHTSFDPKEGKFVG-----------------LPPQWQNILDTLRRPKPVVDPSRITRVQLQ-----------------------------PMKTVVRGSSVPTEGYISGLLNDIQKLSAISSNTLRGRSPTSRRRAQSLG------------------LLGDDQWAADPDMYLQSPQSERTDPHGVYLSCNGGTPAGHRQTPWPEPQSPQALPNGMAAKAQSLGPAEFQGASQRCLQ-LGACLQSSPPGTSPPMATGRRGVKVTKHSSEEARPQSCLVGSAIGRPGGEGSPSPKTQESSLKHRLFRSMFLSTPATG-------------------------------------------------------------SASSSKPVPLPQNKLNSAFRPPQKDSSSNLVAKAQSLPSD------QPTGTFSPLTTSDTSSPQKSLRTAPATGPLP------------GRSSPAGSPRT---------------------------------RHAQISTSNLYLPQDPT---------VAKGALGGEDTGIVTHEQFKAAL--------RMVVDQGDPRLLLDSYVKIGEGSTGIVCLAR-------------------EKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHLNVVEMYKSYLVG-EELWVLMEFLQGGALTDIISQVRLN--------EEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSPPPKLKNSYKVSPVLRDFLERMLVREPQERATAQELLDHPFLLQTGLPECLVPLIQLYRKQTSTC--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQU5-1", "uniprot_id": "PAK6_HUMAN", "id": "Q9NQU5-1", "name": "Serine/threonine-protein kinase PAK 6", "aln": "MFR--KKKKKRPEISAPQNFQHRVHTSFDPKEGKFVG-----------------LPPQWQNILDTLRRPKPVVDPSRITRVQLQ-----------------------------PMKTVVRGSAMPVDGYISGLLNDIQKLSVISSNTLRGRSPTSRRRAQSLG------------------LLGDEHWATDPDMYLQSPQSERTDPHGLYLSCNGGTPAGHKQMPWPEPQSPRVLPNGLAAKAQSLGPAEFQGASQRCLQ-LGACLQSSPPGASPPTGTNRHGMKAAKHGSEEARPQSCLVGSATGRPGGEGSPSPKTRESSLKRRLFRSMFLSTAATA-------------------------------------------------------------PPSSSKPGPPPQSKPNSSFRPPQKDNPPSLVAKAQSLPSD------QPVGTFSPLTTSDTSSPQKSLRTAPATGQLP------------GRSSPAGSPRT---------------------------------WHAQISTSNLYLPQDPT---------VAKGALAGEDTGVVTHEQFKAAL--------RMVVDQGDPRLLLDSYVKIGEGSTGIVCLAR-------------------EKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHFNVVEMYKSYLVG-EELWVLMEFLQGGALTDIVSQVRLN--------EEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSPPPKLKNSHKVSPVLRDFLERMLVRDPQERATAQELLDHPFLLQTGLPECLVPLIQLYRKQTSTC--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PEY8-1", "uniprot_id": "A5PEY8_DANRE", "id": "A5PEY8-1", "name": "non-specific serine/threonine protein kinase", "aln": "MFQRRKKKKRKLEISTPKNFQHRVHTSFDPVQGCFIG-----------------LPPQWQSLIETLKRPKPVVDPSSFTQVQVR-----------------------------PQKSIVRGSFIGHEDYISAAIAQMSRLSVTSSNSLRRRSPSVRKRAQSLG------------------RLG-ELAEAETYEYEELNNTNHRNSSDLHR--------GSRPIQSPQTESRQSPARARSVHEATM----FTGLMPRDILLHRAGCEGTDNAGNKP----------------NQRPVSCLYSQSDG---------AKLNSDQLKMETQR----------------------------------------------------------------------------RPQSTYDFKVNSPNLP--------AASKPNGTSSP------KPGHGIISMQTPRRSSTDNTLKLSTIPADVP------------PAQDSPSEPRQ---------------------------------APSGASSPGLTEPS-------------------------VTHTQFRAAL--------QMVVDPGDPRSYLENFIKIGEGSTGVVCIAR-------------------EKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYRHQNVVEMYKSALVG-EELWVIMEYLQGGALTNIVSETRLT--------EEQIATVCESVLQALCYLHSQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRRSLVGTPYWMAPEVVSKTPYGTEVDIWSLGIMVVEMVDGEPPYFSETPISAMKRLRDEPPPTARNASKISPVLRDFLDSMLTREPQQRSSASDLLQHPFLLQCSSPRCLIPLVEQTRRRTSRC--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. * * . * . : : . : . : . . . . : . : . . : . . : :* : . . :: :: * :. .** * *:*::* * * : * :**:* : * :* ::**:.**:::*:: :: *:*: .: * ::*:*:**:: **:**::: : * *** : . *.* :** : :********.:** . **::******::: . .** ::***********:.: * ::*:******.:**::*****:.: *: *: : . * :. :* :: **. * : *.:: :**.* *: * .*: . ", "identical_positions": 103, "similar_positions": 120, "identity": "11.36%" }, { "cls_id": "homologset.agr.SGD:S000005243", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LJG4-1", "uniprot_id": "A0ABK0LJG4_RAT", "id": "A0ABK0LJG4-1", "name": "Terminal nucleotidyltransferase 4B", "aln": "MDPRIAWFQPEQLGPSNSLWMQIWETTQGLRNLYFNHHCHSSG---ASSASGGSGSGPGSPGGTAPAPAGMFRSGERPLGGLAVP---AEQRDFLPLETTNNNNNHHQPAAWARRAAAGPSASPVPSAPSSPRPAAPLPASESADPASG--------------------------------------------SSNKRKRDNKASTYGLNY------------------SLLQPSGGRAAGGGRADGGGGVYSGTPWKRR--NYNQGVVG---LHEEISDFYEYMSPRPEEEKMRMEVVSRIESVIKELWPSADVQIFGSFKTGLYLPTS-DIDLVVFG----KWENLPLWTLEEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFN-VQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVFT-GGIGSYSLFLMAVSFLQLHPRED--ACIPNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSPIAKCYPNNET-ESILGRIIRVTDEVTTYRDWISKQWGLQNRPEP--SCNGNGVTLIVETQQLDKC-------------NNNLSEENEAPGKCRSKASESLSKHSSNSSSGPVSSSSAT---------------------------------------------------QSSSSDVDSDATPCKTP---------------------------------KQVLCRPPTVSRVGSQDVSLEVSQAVGKMQSTQTTNTANSTNKSQHGSARLFRSS---------------SKGFQG---TAQTSHGA---------------LMTSK--------QHPGKSNTQCYHGKKRRHKRDAPLSELCR--------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q68ED3-1", "uniprot_id": "PAPD5_MOUSE", "id": "Q68ED3-1", "name": "Terminal nucleotidyltransferase 4B", "aln": "----------------------------------------------------------------------MFRSGERPLGGLAVP---AEQRDFLPLETTNNNNNHHQPAAWARRASAGPSASPVPSAPSSPRPAAALPASESTDPASG--------------------------------------------SSNKRKRDNKASTYGLNY------------------SLLQPSGGRAAGGGRADGGGGVYSGTPWKRR--NYNQGVVG---LHEEISDFYEYMSPRPEEEKMRMEVVSRIESVIKELWPSADVQIFGSFKTGLYLPTS-DIDLVVFG----KWENLPLWTLEEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFN-VQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVFT-GGIGSYSLFLMAVSFLQLHPRED--ACIPNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSPIAKYYPNNET-ESILGRIIRVTDEVATYRDWISKQWGLQNRPEP--SCNGNGVTLIVDTQQLDKC-------------NNNLSEEKEALGKCRSNASEPLSKHSSNSSSGPVSSSSAT---------------------------------------------------QSSSSDVDSDATPCKTP---------------------------------KQLLCRPPTVTRVGSQDVSLEVSQAVGKMQSTQTTNTPNNANKSQHGSARLFRSS---------------SKGFQG---TAQTSHGA---------------LMTSK--------QHQGKSNTQYYHGKKRRHKRDAPLSELCR--------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NDF8-1", "uniprot_id": "PAPD5_HUMAN", "id": "Q8NDF8-1", "name": "Terminal nucleotidyltransferase 4B", "aln": "----------------------------------------------------------------------MYRSGERLLGSHALP---AEQRDFLPLETTNNNNNHHQPGAWARRAGS--SASSPPSASSSPHPSAAVPAADPADSASG--------------------------------------------SSNKRKRDNKAS------------------------------GGRAAGGGRADGGGVVYSGTPWKRR--NYNQGVVG---LHEEISDFYEYMSPRPEEEKMRMEVVNRIESVIKELWPSADVQIFGSFKTGLYLPTS-DIDLVVFG----KWENLPLWTLEEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFN-VQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVFT-GGIGSYSLFLMAVSFLQLHPRED--ACIPNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSPIAKYYPNNET-ESILGRIIRVTDEVATYRDWISKQWGLKNRPEP--SCNG------------------------------------------------------------PVSSSSAT---------------------------------------------------QSSSSDVDSDATPCKTP---------------------------------KQLLCRPSTGNRVGSQDVSLESSQAVGKMQSTQTTNTSNSTNKSQHGSARLFRSS---------------SKGFQG---TTQTSHGS---------------LMTNK--------QHQGKSNNQYYHGKKRKHKRDAPLSDLCR--------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1D6UPT1-1", "uniprot_id": "A0A1D6UPT1_DANRE", "id": "A0A1D6UPT1-1", "name": "Terminal nucleotidyltransferase 4A", "aln": "MDPRIAWFQPEQRGPANNLWMHIWDTTQTLGNLYFNNNCN-----------------------TASAKLTTNGDGASSNAADSSS---GRPKDQQGMSGSKPDSEVSEQQDFIPLEAFNNINSSRPGRVVGG--GGQVGGSGVAGVGNE--------------------------------------------LPSKRKRDNKASTYGFN-------------------------RSLLLTDGAEDG----YAGTPWKSR--NYSDGIVG---LHEEIKDFYEYISPRPEEEQMRHEVVARIQRVIKDLWPNAEVCVFGSFSTGLYLPTS-DIDLVVFG----NWETLPLWTLEEALRKRKVADENSIKVLDKATVPIIKLMDSHTEVKVDISFN-VQSGVKAANLIKDYKQQYPVLPYLVLVLKQFLLQRELNEVFT-GGIGSYSLFLMAVSFLQLHCRED--VSSSNPNLGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKSMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKEAFDYAYVILSHAVSPIAKYYPNNKS-ESILGRIIRVTQEVVEYRDWISAQWGQKSSKEPVLNCNANDLTLLVEREELDEC-------------NNNLSED-------------------SVVCTSVPRSKVSS---------------------------------------------------NSSSPSPSSPSSPSSSS---------------------------------SSPSSTASSSSDADSDGTPYKTAKALGGRSTYSENTERISNHRSQNHSASISTPT---------------HKGNKSRQLANKSTQGP---------------HNNPN--------KIQQSSKSVKSNVKKRKPQRDSAHEDLCR--------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6PB75-1", "uniprot_id": "PAPD7_MOUSE", "id": "Q6PB75-1", "name": "Terminal nucleotidyltransferase 4A", "aln": "MDPRVAWIQPEQKGPANALWMQIWETSQGVGRGGSGFAS-------YFCLNSPALDTAAAPGAAGRAAPAAGGPGPAPAASSPPP--APGPAALPPALLTALGPAADSARRLHKSPSLSSSSSSSSSNAESGTESPGCSSSSSSSTSLGRAGSGR--TFFSFADGA------AHAHPGPRGSTPAGSPPQHQFHPGRRKRENKASTYGLN-------------------YLLSGSRAATLSGGGGPGAQAARPGTPWKSR--AYSPGIQG---LHEEIIDFYNFMSPCPEEAAMRREVVKRIETVVKDLWPTADVQIFGSFSTGLYLPTS-DIDLVVFG----KWERPPLQLLEQALRKHNVAEPCSIKVLDKATVPIIKLTDQETEVKVDISFN-METGVRAAEFIKNYMKKYSLLPYLILVLKQFLLQRDLNEVFT-GGISSYSLILMAISFLQLHPRID--ARRADENLGMLLVEFFELYGRNFNYLKTGIRIKEGGAYIAKEEIMKAMTSGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKQVFDYAYIVLSHAVSPLARSYPNRDS-ESTLGRIIKVTQEVIDYRRWIKEKWG----SRILPSPDLDNRIKIKERIT-----------------TCNGEQMQSREPSSPYTQRLTLSLSSPQLLSSGSSASSVS---------------------------------------------------SLSGSDIDSDTPPCTTPSVYQFSLQAPTTLMASLPTALPMPSSKPQPAASRTLIMTTNNQTRVTIPPPTLGVAPVPCRQAGVDGTTSLKAVHSVTSPAIPSASPNPLSSPHL-------YHKQHNGMKLSMKGSHNHTQGGGYSSVGSGAVRPPVGN--------RGHHQYNRTGWRRKKHAHTRDSLPVSLSR--------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZSY1-1", "uniprot_id": "D3ZSY1_RAT", "id": "D3ZSY1-1", "name": "Terminal nucleotidyltransferase 4A", "aln": "MDPRVAWIQPEQKGPANALWMQIWETSQGVGRGGSGFAS-------YFCLNSPALDTAAAPGAAGRAAPAAGGPGPAPAASSPPP--APGPAALPPALLTALGPAADGARRLHKSPSLSSSSSSSS-NAESGTESPGCSSSSSSSTSLGRAGSGR--TFFSFADGA------AHAHPGPRGPTPAGSPPQHQFHPGRRKRENKASTYGLN-------------------YLLSGSRAATLSGGGGPGAQAARPGTPWKSR--AYSPGIQG---LHEEIIDFYNFMSPCPEEAAMRREVVKRIETVVKDLWPSADVQIFGSFSTGLYLPTS-DIDLVVFG----KWERPPLQLLEQALRKHNVAEPCSIKVLDKATVPIIKLTDQETEVKVDISFN-METGVRAAEFIKNYMKKYSLLPYLILVLKQFLLQRDLNEVFT-GGISSYSLILMAISFLQLHPRID--ARRADENLGMLLVEFFELYGRNFNYLKTGIRIKEGGAYIAKEEIMKAMTSGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKQVFDYAYIVLSHAVSPLARSYPNRDS-ESTLGRIIKVTQEVIDYRRWIKEKWG----SRIVPSPDLDNRIKIKERVT-----------------TCNGEQMQSREPSSPYSQRLTLSLSSPQLLSSGSSASSVS---------------------------------------------------SLSGSDIDSDTPPCTTPSVYQFSLQAPTTLMAGLPTALPVPSSKPQPAASRTLIMTTNNQTRVTIPPPTLGVAPVPCRQAGVDGTTSLKAVHNVTSPAIPSASPNPLSSPHL-------YHKQHNGMKLSMKGSHNHTQGGGYSSVGSGAVRPPVGN--------RGHHQYNRTGWRRKKHAHTRDSLPVSLSR--------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5XG87-1", "uniprot_id": "PAPD7_HUMAN", "id": "Q5XG87-1", "name": "Terminal nucleotidyltransferase 4A", "aln": "MDPRVAWIQPEQKGPANALWMQIWETSQGVGRGGSGFAS-------YFCLNSPALDTAAAAGAAGRGS---GGLGPALPAASPPPPGPTAPAALPPALLTALGPAAEGARRLHKSPSLSSSSSSSSSNAESGTESPGCSSSSSSSASLGRPGGGRGGAFFNFADGAPSAPGTANGHPGPRGPAPAGSPSQHQFHPGRRKRENKASTYGLN-------------------YLLSGSRAAALSGGGGPGAQAPRPGTPWKSR--AYSPGIQG---LHEEIIDFYNFMSPCPEEAAMRREVVKRIETVVKDLWPTADVQIFGSFSTGLYLPTS-DIDLVVFG----KWERPPLQLLEQALRKHNVAEPCSIKVLDKATVPIIKLTDQETEVKVDISFN-METGVRAAEFIKNYMKKYSLLPYLILVLKQFLLQRDLNEVFT-GGISSYSLILMAISFLQLHPRID--ARRADENLGMLLVEFFELYGRNFNYLKTGIRIKEGGAYIAKEEIMKAMTSGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKQVFDYAYIVLSHAVSPLARSYPNRDA-ESTLGRIIKVTQEVIDYRRWIKEKWG----SKAHPSPGMDSRIKIKERIA-----------------TCNGEQTQNREPESPYGQRLTLSLSSPQLLSSGSSASSVS---------------------------------------------------SLSGSDVDSDTPPCTTPSVYQFSLQAPAPLMAGLPTALPMPSGKPQPTTSRTLIMTTNNQTRFTIPPPTLGVAPVPCRQAGVEGTASLKAVHHMSSPAIPSASPNPLSSPHL-------YHKQHNGMKLSMKGSHGHTQGGGYSSVGSGGVRPPVGN--------RGHHQYNRTGWRRKKHTHTRDSLPVSLSR--------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58I0Y0-1", "uniprot_id": "A0AC58I0Y0_DANRE", "id": "A0AC58I0Y0-1", "name": "Terminal nucleotidyltransferase 4A", "aln": "MDPRVAWIQPEQKGPANALWMRVWETSQ-VNRTNTGQHQNHHHHHHNFCVNSPAFDVYKTVASNANNSTNIKNNGTAIPGSGSAVLALNGNAVDGEMSQKTGGSVVDSASSCTRIR--TTSPNVIAGNMNKGQPFFTLNESVLNNVNHHHHPPHPHLRHFHQEQQS-------CMKRHPSYPTAIHNHHHHHHHPGRRKSDNKASTYGIN-------------------YLLSN-----WTNG-----NYESSGTPWKTR--KYSPGVDG---LHEEIMDFYNFMSPRPEEATMRQEVVDRIESVIKELWPTADVQIFGSFSTGLFLPTSSDIDLVVFG----KWEKPPLQQLEQALRKHSVAEPYSIKVLDKATVPIIKLTDQETEVKVDISFN-VETGIKAASFIKEYVKKYTVLPYLIFVLKQFLLQRDLNEVFT-GGISSYSLILMVISFLQLHPRID--TRNPNMNLGILLIEFFELYGRHFNYLKTGIRIKNGGAYMAKEDIMKAMSNGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKEAFDYAYIILSHAVSPLARSYPNKDS-DSTLGRIIKVTQEVIDYREWIIKKWGGRHNSRIERNPGSSHKEHVDQVETGSLL-------------GVGVEEQQQRDSVSPHSADSPMSLSSPQQHSS---ASSAS---------------------------------------------------SLSGSDIDSDSTPYVAPPVAPFPLQILAP--GPLPPALQMG----KASIAAALGMPPVTQARVSIPG-NLSLHTLPGRQVCMADGP--PSYLHMPPPAVPPAPPSPLPSP---------LHHPKAGPKFPLKGFHNP------AVVHS----PVLSN--------RGHIQYNRNTWRRRK----RDSLPASVSR--------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KVS9-1", "uniprot_id": "TRF41_DROME", "id": "Q7KVS9-1", "name": "Non-canonical poly(A) RNA polymerase protein Trf4-1", "aln": "MDPFVGWFQKEQEGPSLCTWLKIWETNAQEMGALLNQQLQQATTINGSTSSSSSSSNSGNNNNNNNNNIINNTITNTTNNTGNNSSAKPYLSRPYSSLNRVLNFRADSLEILQQQQQQQQLNGTTQRNSTNINTTSGGSTSSSADSTTNRDNNSPANSSSTNGPGAGTGTSTGAGGTGTNSPATTASSTAATTTGPATSMSDTSNNPPQSTTTPASRTNSIYYNPSRKKRPENKAGGAHYYMNNHMEMIAKYKGEPWRKPDYPYGEGVIG---LHEEIEHFYQYVLPTPCEHAIRNEVVKRIEAVVHSIWPQAVVEIFGSFRTGLFLPTS-DIDLVVLG----LWEKLPLRTLEFELVSRGIAEACTVRVLDKASVPIIKLTDRETQVKVDISFN-MQSGVQSAELIKKFKRDYPVLEKLVLVLKQFLLLRDLNEVFT-GGISSYSLILMCISFLQMHPRG---IYHDTANLGVLLLEFFELYGRRFNYMKIGISIKNGGRYMPKDELQRDMVDGHRPSLLCIEDPLTPGNDIGRSSYGVFQVQQAFKCAYRVLALAVSPLNLLGIDPRV-NSILGRIIHITDDVIDYREWIRENFEHLVVVDRISPLPTAAPTAYATANGAPKYVIMPSGAVVQQLYHHPVQVPTAHGHSHAHSHSHGHAHPGAHLCQPYVTGTTVSAVTTTTTMAVVTVGVSAGGVQQQQQQQNATAHTHSQQQTQNQSQSRHRRGSTSSGDDSEDSKDGDVVETTSSAQEVVDIALSTPNGLANMSMPMPVHAVGMPASNSWSGNGNGNGNSSSSTGSSPEIAHIAAQEMDPELEDQQQQQQHQETSGGNGFIRPGDVGTGSNRGGGDGSGGRNYNQRNNHNSSGYYHQQYYVPPPMQQQLSKSNSSSNYHQQHHHSHSHGNHSHRQQHHHQQQHHHQQRPQHLRVGGGNRYQKSLGGSPIISAGNASNSSSNCSNSSSSSGSNNSRLPPLRGTLVNSSSAISIISISSESSIASSSSSSSRSGQDQQRDER", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VC07-1", "uniprot_id": "TRF42_DROME", "id": "Q9VC07-1", "name": "Inactive non-canonical poly(A) RNA polymerase protein Trf4-2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCDEAN-----------------------------------------------PAKPWQLPDVVYGNGIPALCLLHQEIEQFYNYIRSTPTEFCLRAGAVRRIEDVVLSIWPSASVDLFGSFRTGLNLPDS-DIDLVVYYK---FWNPRLLHELQNELVSQGVTDPDTVTVLDKASVPVVKFTDLISRIRFDVTFNSVASGVQAADLIKDFIRHFPELPKLVMVLKQFLSLHGFNEVYNSGGVSSYALTLMVISFLQQHARSNR-RLSEHSKLALLLIQFLDYYGRKFDFFKYGISVLGQGGCVEKARLRSTLGENNWQSVLCIEDPVTPTNDIGRSSYGVLGVMQGFGAAFVKLSKLVD----SDSSKIV-GPILANIVEVPQSIINYRAWVHYNFQHLLTPE----LPCADS-----------------------------------------------------LVQPSPTGSTS---------------------------------------------------PSASASASEDERSG------------------------------------GPAT-------IGFGRCDDPPQNIDIVADLANLKMN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48561-1", "uniprot_id": "TRF5_YEAST", "id": "P48561-1", "name": "Poly(A) RNA polymerase protein 1", "aln": "MTRLKAKYSPTKGKRKEDKHTKRMRKSSFTRTQKMLEVFN-----------------DNRSHFNKYESLAIDVEDDDTFGNLVLMENDKSDVDIPVIEEVTSSEDEQRAESSKRNNSLEDNQDFIAFSDSSEDETEQIKEDDDERSSFL--------------------------------------------LTDEHEVSKLTSQQSLN------------------------------------TESACNVEYPWIRNHCHSKQRRIAD-WLTSEIKDFVHYISPSKNEIKCRNRTIDKLRRAVKELWSDADLHVFGSFATDLYLPGS-DIDCVVNSRNRDKEDRNYIYELARHLKNKGLAIR--MEVIVKTRVPIIKFIEPQSQLHIDVSFE-RTNGLEAAKLIREWLRDSPGLRELVLIIKQFLHSRRLNNVHT-GGLGGFTVICLVYSFLNMHPRIKSNDIDVLDNLGVLLIDFFELYGKNFGYDDVAISISDGYASYIPKSCWRTLEPSRSKFSLAIQDPGDPNNNISRGSFNMKDIKKAFAGAFELLVNKCWELNSATFKDRVGKSILGNVIKYRGQKRDFNDERDLVQNKAIIENERYHKRRTRIVQEDLFIN------------------------------------DTEDLPVEEIYKLDEPAKKKQ---------------------------------------------------KAKKDKREGEIKKSAIP--------------------------------------SPPPDFGVSRSKLKRKVKKTDQGSLLHQNNLSIDDLMGLSENDQES-------------------DQDQKGRDTPSGQDEKS------------------------------PLETKTVDAQTRRDYWLSKGQAL------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. ** . * .** .* .:: . * * .: ::. .: .:*. * : :**** *.* ** * *** ** : : * * .: :: : *: *: **::*: : :.::.*::*: .*:.:*.:*:.: :. . * *::::**** : :*:*.. **:..::: : ***: * * : .:**::*:: **:.*.: . .* : : . * *:** * *::.*.*:. : : * *: * . . *..::. . :. .. . .. ", "identical_positions": 70, "similar_positions": 114, "identity": "6.9%" }, { "cls_id": "homologset.agr.SGD:S000005245", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P12001-1", "uniprot_id": "RL18_RAT", "id": "P12001-1", "name": "Large ribosomal subunit protein eL18", "aln": "MGVDIRHNKD-RKVRRKEPKSQDIYLRLLVKLYRFLARRTNSTFNQVVLKRLFMSRTNRPPLSLSRMIRKMKLPGRENKTAVVVGTITDDVRILEVPKLKVCALRVSSRARSRILKAGGKILTFDQLALESPKGRGTVLLSGPRKGREVYRHFGKAPGTPHSHTKPYVRSKGRKFERARGRRASRGYKN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35980-1", "uniprot_id": "RL18_MOUSE", "id": "P35980-1", "name": "Large ribosomal subunit protein eL18", "aln": "MGVDIRHNKD-RKVRRKEPKSQDIYLRLLVKLYRFLARRTNSTFNQVVLKRLFMSRTNRPPLSLSRMIRKMKLPGRENKTAVVVGTVTDDVRILEVPKLKVCALRVSSRARSRILKAGGKILTFDQLALESPKGRGTVLLSGPRKGREVYRHFGKAPGTPHSHTKPYVRSKGRKFERARGRRASRGYKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07020-1", "uniprot_id": "RL18_HUMAN", "id": "Q07020-1", "name": "Large ribosomal subunit protein eL18", "aln": "MGVDIRHNKD-RKVRRKEPKSQDIYLRLLVKLYRFLARRTNSTFNQVVLKRLFMSRTNRPPLSLSRMIRKMKLPGRENKTAVVVGTITDDVRVQEVPKLKVCALRVTSRARSRILRAGGKILTFDQLALDSPKGCGTVLLSGPRKGREVYRHFGKAPGTPHSHTKPYVRSKGRKFERARGRRASRGYKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VS34-1", "uniprot_id": "RL18_DROME", "id": "Q9VS34-1", "name": "Large ribosomal subunit protein eL18", "aln": "MGIDINHKYD-RKVRRTEPKSQDVYLRLLVKLYRFLQRRTNKKFNRIILKRLFMSKINRPPLSLQRIARFFKAANQPESTIVVVGTVTDDARLLVVPKLTVCALHVTQTARERILKAGGEVLTFDQLALRSPTGKNTLLLQGRRTARTACKHFGKAPGVPHSHTRPYVRSKGRKFERARGRRSSCGYKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX50-1", "uniprot_id": "RL18B_YEAST", "id": "P0CX50-1", "name": "Large ribosomal subunit protein eL18B", "aln": "MGIDHTSKQHKRSGHRTAPKSDNVYLKLLVKLYTFLARRTDAPFNKVVLKALFLSKINRPPVSVSRIARALKQEGAANKTVVVVGTVTDDARIFEFPKTTVAALRFTAGARAKIVKAGGECITLDQLAVRAPKGQNTLILRGPRNSREAVRHFGMG---PHKGKAPRILSTGRKFERARGRRRSKGFKV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* : . *. :*. ***:::**:****** ** ***: **:::** **:*: ****:*:.*: * :* . :.* *****:***.*: .** .*.**:.: ** :*::***: :*:****: :*.* .*::* * *..* . :*** . **. . * : *.*********** * *:* ", "identical_positions": 90, "similar_positions": 55, "identity": "47.62%" }, { "cls_id": "homologset.agr.SGD:S000005246", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CZX8-1", "uniprot_id": "RS19_MOUSE", "id": "Q9CZX8-1", "name": "Small ribosomal subunit protein eS19", "aln": "MPGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDEN-WFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVRPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17074-1", "uniprot_id": "RS19_RAT", "id": "P17074-1", "name": "Small ribosomal subunit protein eS19", "aln": "MPGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDEN-WFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVRPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P39019-1", "uniprot_id": "RS19_HUMAN", "id": "P39019-1", "name": "Small ribosomal subunit protein eS19", "aln": "MPGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDEN-WFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZSH6-1", "uniprot_id": "D3ZSH6_RAT", "id": "D3ZSH6-1", "name": "", "aln": "--GVTVKDFNQQEFIRALAVFLKKSGKLKVPEWVDTVKLVKHKELAPYDEN-WFYTRAASTARHLYLRGGAGVGSVTKIYGGWQRNSVRPSHFSRGSKSVARRVLQASEGLKMVEKDQDGDHKLTPQGQRDLGSPD---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7KS38-1", "uniprot_id": "RS19B_DROME", "id": "Q7KS38-1", "name": "Small ribosomal subunit protein eS19B", "aln": "MPGVTVKEIDQHVLTKNMAAFLKKSGKIFVPEQAVYMKTGKFKETAPTDDD-WFYTRCASIMRHLYLRSPAGVGAFTKVYSGRKRNGVRPSKHCRSSDGCIRKALQALEAANMVERHPDGGRKLTPQGQRNLDRIANKIVAKQRERSAPVSMIITT-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39018-1", "uniprot_id": "RS19A_DROME", "id": "P39018-1", "name": "Small ribosomal subunit protein eS19A", "aln": "MPGVTVKDIDQHAVTKAVAVFLKKTGKLKVPDQMDIVKTAKFKELAPYDPD-WFYVRCASILRHLYHRSPAGVGSITKIYGGRKRNGVHPSHFCRAADGAARKALQALEHARLVEKHPDGGRKLSSIGQRDLDRIANQIVFKQRDAAKQTGPIVISK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07281-1", "uniprot_id": "RS19B_YEAST", "id": "P07281-1", "name": "Small ribosomal subunit protein eS19B", "aln": "MAGVSVRDVAAQDFINAYASFLQRQGKLEVPGYVDIVKTSSGNEMPPQDAEGWFYKRAASVARHIYMRKQVGVGKLNKLYGGAKSRGVRPYKHIDASGSINRKVLQALEKIGIVEISPKGGRRISENGQRDLDRIAAQTLEEDE-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:*::. : . . * **:: **: ** :* . :* .* * : *** *.** **:* * .*** ..*:*.* : ..* * :. .: . *:.*** * :** .*.:::: ***:*. ", "identical_positions": 44, "similar_positions": 41, "identity": "28.03%" }, { "cls_id": "homologset.agr.SGD:S000005249", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LS63-1", "uniprot_id": "F1LS63_RAT", "id": "F1LS63-1", "name": "", "aln": "-------------------------MKIDLEVSEPVNFSSGDHQHLVHKAAIKSNSGKLDQQPFTSSSGDRPQEAIKYP------------------------------------------YPRSRDGANAYAV-------------QISEDATPPNESVNLSGPFENTSIRKGFIVKVFVVLSAQLLITAAIISIFVFCEAVRKWIIAMPWFMYALLPAVLIVIVILACCRDIR------------------------------RQVPANYILLVFFTILEGLLLGSMSVFYKADEILWATGATTAVTLVLTLFALQTKWDFTLLNGM-----LFVFTSVLVIYGIVT----LVVRSYWLHLVYSALGTLLFSMYLVMDVQMMVGG-RYHYEIDPEEYIFAALNIYVDIINLFIFILDLIGR-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VFM3-1", "uniprot_id": "Q9VFM3_DROME", "id": "Q9VFM3-1", "name": "", "aln": "--------------------------MLDILQ-EPV------HQY-----------------------GNRSHQAECIP------------------------------------------LGR----YTAYGS-------------EIGQDD--PDKGLG----FCSASIRRGFIRKVYLILLAQLITSLVVIVSLTADKRVRLMVAESTWIFVVAILIVVFSLVALGCNEDLR------------------------------RQTPANFIFLSAFTIAESFLLGVAACRYAPMEIFMAVLITASVCLGLTLFALQTRYDFTVMGGL-----LVSCLIILLFFGIVT----IFVGGHMVTTIYASLSALLFSVYLVYDTQLMMGG-KHRYSISPEEYIFAALNIYMDVMNIFLDILQLIGGSD---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4ABI5-1", "uniprot_id": "Q4ABI5_DROME", "id": "Q4ABI5-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------MPCFSG-------------RRRERE---------PMYFEDRYSRRIFISRVLMIVAINLLVTTLIMTFCVFHMGARKFLLKHWYIGLVGMGIILIFSFMICCCSFLF------------------------------RSSPCKYILLVIYVLAHSTVVCSAAVRYQPKLVFIAVASCAAIVVMLCLFARFAPCDFTGCWIF-----VFVLSLVVLIMGIVA----IFFP--TIRIVYASLGVLLFCVYIVIDVQMIIGGGTHKNEFDESDYVLAAMSLYSDIVFLFLYLLDLIGLIDD--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9ESF4-1", "uniprot_id": "LFG1_MOUSE", "id": "Q9ESF4-1", "name": "Protein lifeguard 1", "aln": "--------------MSHEKSFLVSGDSYPPQN---IVGPQAPMPPYVQAPYPGAPYPQAPFQPSPYGQPGYPHGPSPYPQGGYPQGPYPQGGYPQGPYPQ--------------------SPFPPNPYGQPPPF--QDPGSPQHGNYQEEGPPSYYDNQDFPAVNWD-KNIRQAFIRKVFLVLTLQLSVTLSTVAIFTFVGEVKGFVRENVWTYYVSYAIFFISLIVLSCCGDFR------------------------------RKHPWNLVALSILTVSLSYMVGMIASFYNTEAVIMAVGITTAVCFTVVIFSMQTRYDFTSCMGV-----LLVSVVVLFIFAILC----IFIRNRILEIVYASLGALLFTCFLAVDTQLLLGN--KQLSLSPEEYVFAALNLYTDIINIFLYILTIIGRAKE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P6R0-1", "uniprot_id": "LFG1_RAT", "id": "Q6P6R0-1", "name": "Protein lifeguard 1", "aln": "--------------MSHEKSFLVSGDSYPPPNPGYPVGPQAPMPPYVQPPYPGAPYPQAAFQPSPYGQPGYPHGPGPYPQGGYPQGPYPQGGYPQGPYPQ--------------------SPFPPNPYGQPPPF--QDPGSPQHGNYQEEGPPSYYDNQDFPSVNWD-KSIRQAFIRKVFLVLTLQLSVTLSTVAIFTFVGEVKGFVRANVWTYYVSYAIFFISLIVLSCCGDFR------------------------------RKHPWNLVALSILTISLSYMVGMIASFYNTEAVIMAVGITTAVCFTVVIFSMQTRYDFTSCMGV-----LLVSVVVLFIFAILC----IFIRNRILEIVYASLGALLFTCFLAVDTQLLLGN--KQLSLSPEEYVFAALNLYTDIINIFLYILTIIGRAKE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z429-1", "uniprot_id": "LFG1_HUMAN", "id": "Q7Z429-1", "name": "Protein lifeguard 1", "aln": "--------------MSHEKSFLVSGDNYPPPNPGYPGGPQPPMPPYAQPPYPGAPYPQPPFQPSPYGQPGYPHGPSPYPQGGYPQGPYPQGGYPQGPYPQEGYPQGPYPQGGYPQGPYPQSPFPPNPYGQPQVFPGQDPDSPQHGNYQEEGPPSYYDNQDFPATNWDDKSIRQAFIRKVFLVLTLQLSVTLSTVSVFTFVAEVKGFVRENVWTYYVSYAVFFISLIVLSCCGDFR------------------------------RKHPWNLVALSVLTASLSYMVGMIASFYNTEAVIMAVGITTAVCFTVVIFSMQTRYDFTSCMGV-----LLVSMVVLFIFAILC----IFIRNRILEIVYASLGALLFTCFLAVDTQLLLGN--KQLSLSPEEYVFAALNLYTDIINIFLYILTIIGRAKE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B4U7-1", "uniprot_id": "A0A8M2B4U7_DANRE", "id": "A0A8M2B4U7-1", "name": "", "aln": "--------------MSQNKGYSRFDNAVDGDDPSPPPPPGFVMPPAYEAAVQYGHADATVPVAVPVGPP-YAFESPAYGQG--------VSGYPQQPYPVA-------------------APYSTDPYSQPFPN------VVAMGEPGQSNDPPEYDSDQFTSSGLDNKEIRRVFIRKVFSVLSLQLAITTAFVAIFTFEPHVKLFVMQNSWTYWVGYLVFLVPYFVILCCGEFR------------------------------RKHPWNLICLSVLTLAMSYMVGVISSFYDTDIVIMAIGITVVVCFTVIIFSMQTKYDFTSCYGV-----LFVCGIVLFVFGILC----IIFYSKIMDLIYSTLGALLFTCFLAVDTQLLLGN--KNLSLSPEEYIFASLNLYLDIIQIFLFILRILGRSRS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1PSJ5-1", "uniprot_id": "A0A8M1PSJ5_DANRE", "id": "A0A8M1PSJ5-1", "name": "", "aln": "--------------MAD----------VENQKPVAESGPMYPPPPYMPPSYPIG-----PVYPQPVPPP---------------------VGFIAPVLPP----------------------------EEAAVN------KTEETSPETAVLPP--EEHQVFVSAFDDNKVQKAFIRKVFSVVTIQLLVTFTVVCVFTFSKTVKEAVQKNIWIYISSYIVFMVVALCLSVSSTFS------------------------------RKHPWNLVGLSMVTLSLSYMVGTVASYHNTTAVIIALGSTLVISFTIIIFSAQTCLDFTICNGV-----LLILSVDLLMFGFFS----IFFYSSVLQIVYGCLGALLYALFLAVDCQLVMGR--QKYSLDPEEYIFAALIIYLDIIMIFLYILMILGGGSKN-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BJZ3-1", "uniprot_id": "LFG3_MOUSE", "id": "Q8BJZ3-1", "name": "Protein lifeguard 3", "aln": "------------------------------MSNPSAPPPYEDHNPLYPG------SPPPGGYGQPSVLPGGYPAYPAY--------------PQPGYGHPA-------------------GYPQPVPPVHPMPM-------NYG--HDYNEEERAGS-DSFRPGEWDDRKVRHSFIQKVYCIISVQLLITVAIIAIFTFVEPVGKYVRNNVAVYYVSYAVFLVTYLTLACCQGPR------------------------------RRFPWDIILLTIFTLALGFVTGTISSMYENKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGL-----FCVLGIVLMVTGIVTSIVLIFKYIYWLHMVYAALGAICFTLFLAYDTQLVLGN--RKHTISPEDYITGALQIYTDIVYIFTFVLQLVGS-RD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969X1-1", "uniprot_id": "LFG3_HUMAN", "id": "Q969X1-1", "name": "Protein lifeguard 3", "aln": "------------------------------MSNPSAPPPYEDRNPLYPG------PPPPGGYGQPSVLPGGYPAYPGY--------------PQPGYGHPA-------------------GYPQPMPPTHPMPM-------NYGPGHGYDGEERAVS-DSFGPGEWDDRKVRHTFIRKVYSIISVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPR------------------------------RRFPWNIILLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGL-----FCVLGIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGN--RKHTISPEDYITGALQIYTDIIYIFTFVLQLMGD-RN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2K356-1", "uniprot_id": "A0A0G2K356_RAT", "id": "A0A0G2K356-1", "name": "", "aln": "RLISSASYWSGFWDWWKEVIFFPVSWGFVLIREPALLPVNVNHSHLARGWGLKWTSALSGGLGGLAAPPHWRRRETGRG-----------TEPQPSRAQPS-------------------PRHRPEAQAVLRVR-------NSAG-HDYSEEERAGS-DSFGPGEWDDRKVRHTFIQKVYCIISVQLLITVAIIAVFTFVEPVSEYVRSNVAVYYVSYAVFIVTYLILVCCQGPR------------------------------RRFPWNIILLTIFTLALGFMTGAISSMYETKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGL-----ICVLGIVLAVTGAVTSVVLFFEYIYWLHMVYAGLGAICFTLFLAYDTQLVLGN--RKHTISPEDYITGALQIYTDIVYIFTFVLQLVGN-RD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K097-1", "uniprot_id": "LFG2_MOUSE", "id": "Q8K097-1", "name": "Protein lifeguard 2", "aln": "------------------------------MTQGKLSVAN--KAPGTEGQQHQANGEKKDAPAVPSAPP-SYEEATSG------------EGLKAGTFPQG-------------------PTAVPLHPSWAYVD-------PSGS-SGYEGGFPAGHHEHFTTFSWDDQKVRRLFIRKVYTILLVQLLVTLAVVALFTFCDVVKDYVQANPGWYWASYAVFFATYLTLACCSGPR------------------------------RHFPWNLILLTIFTLSMAYLTGMLSSYYNTTSVLLCLVITALVCLSVTIFSFQTKFDFTSCQGV-----LFVLLMTLFFSGLLLAVLLPFQYVPWLHAVYAVLGAGVFTLFLAFDTQLLMGN--RRHSLSPEEYIFGALNIYLDIIYIFTFFLQLFGTNRE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88407-1", "uniprot_id": "LFG2_RAT", "id": "O88407-1", "name": "Protein lifeguard 2", "aln": "------------------------------MTQGKLSVAN--KAPGTEGQQ-QANGEKKDAPAVPSAPP-SYEEATSG------------EGLKAGAFPQG-------------------PTAVPLHPSWAYVD-------PSSS-SGYEGGFPAGHHELFSTFSWDDQKVRQLFIRKVYTILLVQLLVTLAVVALFTFCDVVKDYVQANPGWYWASYAVFFATYLTLACCSGPR------------------------------RHFPWNLILLTIFTLSMAYLTGMLSSYYNTTSVLLCLGITALVCLSVTIFSFQTKFDFTSCHGV-----LFVLLMTLFFSGLLLAILLPFQYVPWLHAVYAVLGAGVFTLFLAFDTQLLMGN--RRHSLSPEEYIFGALNIYLDIIYIFTFFLQLFGTNRE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BWQ8-1", "uniprot_id": "LFG2_HUMAN", "id": "Q9BWQ8-1", "name": "Protein lifeguard 2", "aln": "------------------------------MTQGKLSVAN--KAPGTEGQQ-QVHGEKKEAPAVPSAPP-SYEEATSG------------EGMKAGAFPPA-------------------PTAVPLHPSWAYVD-------PSSS-SSYDNGFPTGDHELFTTFSWDDQKVRRVFVRKVYTILLIQLLVTLAVVALFTFCDPVKDYVQANPGWYWASYAVFFATYLTLACCSGPR------------------------------RHFPWNLILLTVFTLSMAYLTGMLSSYYNTTSVLLCLGITALVCLSVTVFSFQTKFDFTSCQGV-----LFVLLMTLFFSGLILAILLPFQYVPWLHAVYAALGAGVFTLFLALDTQLLMGN--RRHSLSPEEYIFGALNIYLDIIYIFTFFLQLFGTNRE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QZ65-1", "uniprot_id": "F1QZ65_DANRE", "id": "F1QZ65-1", "name": "", "aln": "------------------------------MSLPAAPPS---YAEATAGDKEQGSGSFTYASQPPPMPPPTMPMHPSW------------AYVHPGPSPGY-------------------SNAYAADMSSPFSD-------PSSS-NSFDG----------LGSNWEDKNIRRMFIRKVFCILMVQLMVTFSVVSLFTFCEPVRKFVQYNRVFYLTSYMTFMGTYLMLVCSTNAR------------------------------RRYPTNMILLAIFTLAMSYMAGMLASYHNTKVVMLSVGITALVCLAITLFCFQSRVDFTTCHGL-----LFSLMMVLMITGLLLFFTAPFGYIPWLHTAYAGFGALVFTLFLAFDMQLLIGN--RRYSLNPEEHVFGAICLYMDVVYIFLFFLQLFGS-RE--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9DA39-1", "uniprot_id": "LFG4_MOUSE", "id": "Q9DA39-1", "name": "Protein lifeguard 4", "aln": "---------------------------------------------------------------MADTDPGYPRSS------------------------------------------------------------------------------IEDDFNYGSCVASASVHIRMAFLRKVYSILSLQVLLTTVTSALFLYFQALRTFVHESPALIVVFALGSLGLIFALTLHR---------------------------------HTHPLNLYLLFAFTLSESLAVAAVVTFYDVYLVLQAFIMTTAVFLGLTAYTLQSKRDFTKFGAG-----LFAGLWILCLAGFLKLFF----YSETMELVLASLGALLFCGFIIYDTHSLMHR------LSPEEYVIAAISLYMDIINLFLHLLKFLEAVNKK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LRB3-1", "uniprot_id": "A0ABK0LRB3_RAT", "id": "A0ABK0LRB3-1", "name": "", "aln": "---------------------------------------------------------------MADTDPRYPRSS------------------------------------------------------------------------------IEDDFNYGSCVASASVHIRMAFLRKVYSILSLQVLLTTVTSALFLYFETLRTFVHDSPALIVVFALGSLGLIFALTLHR---------------------------------HTHPLNLYLLFAFTLSEALTVATVVTFYDGHLVLHAFILTAAVFLGLTAYTLQSKRDFSKFGAG-----LFACLWILCLAGFLKVFF----YSQTVELVLASLGALLFCGFIIYDTHSLMHR------LSPEEYVLAAISLYLDIINLFLHLLKFLDAVNKK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HC24-1", "uniprot_id": "LFG4_HUMAN", "id": "Q9HC24-1", "name": "Protein lifeguard 4", "aln": "---------------------------------------------------------------MADPDPRYPRSS------------------------------------------------------------------------------IEDDFNYGSSVASATVHIRMAFLRKVYSILSLQVLLTTVTSTVFLYFESVRTFVHESPALILLFALGSLGLIFALILNR---------------------------------HKYPLNLYLLFGFTLLEALTVAVVVTFYDVYIILQAFILTTTVFFGLTVYTLQSKKDFSKFGAG-----LFALLWILCLSGFLKFFF----YSEIMELVLAAAGALLFCGFIIYDTHSLMHK------LSPEEYVLAAISLYLDIINLFLHLLRFLEAVNKK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48558-1", "uniprot_id": "BXI1_YEAST", "id": "P48558-1", "name": "Bax inhibitor 1", "aln": "---------------------------------------------------------------MSGPPPPYEEQSSHLY-------------------------------------------------GQPASS-------------QDGNAFIPEDFKYSTVVISCEPIIRQRFMHKVYSLLSCQLLASLSFCYWASVSTSLQNFIMSHIALFYICMVVSLVSCIWLAVSPRPEDYEASVPEPLLTGSSEEPAQEQRRLPWYVLSSYKQKLTLLSIFTLSEAYCLSLVTLAYDKDTVLSALLITTIVVVGVSLTALSERFENVLNSATSIYYWLNWGLWIMIGMGLTALLFGWNTHSSKFNLLYGWLGAILFTAYLFIDTQLIFRK------VYPDEEVRCAMMLYLDIVNLFLSILRILANSNDDN", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A1Z773-1", "uniprot_id": "A1Z773_DROME", "id": "A1Z773-1", "name": "", "aln": "---------------------------MDSPKKETGFLDKASLYAWFNFVPLPENSDRYPPISLSAPPTENESQDTN---------------------------------------------------SDPKDG------------EHLVENGMISHDLIVKSNVFEDPTIRMGFVRKVFGILLAQLLFTLAVIAIFSYHQPTKDFMHENFLLVLVAMIVNIIVLSTIVCVENVR------------------------------RRHPVNLICLALYTFTMSLLLGTASSQMDSNVVISAVAITTLLVIALSIYAVQTKYDYTAAGGV-----ILTFVIILIVLSVCG----VWMPDFVDSLPITCLCTFIGCFFLIADMQSIVGG-NRSEQLDPEEYVFAALTLYVDVVRIFIYILRILEKFY---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: :* :: :: : : . : . * . . :: . : . : : . : . . :: * : :. . .: : :: :* *:: :* .* :. ", "identical_positions": 8, "similar_positions": 43, "identity": "1.87%" }, { "cls_id": "homologset.agr.SGD:S000005250", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A040-1", "uniprot_id": "D4A040_RAT", "id": "D4A040-1", "name": "Small ribosomal subunit protein uS11m", "aln": "--MQVVRN-----SGSWLLRSWAGSGMT-RLVAITPAKSIHTGAPRLEDSAARQNTEKEAAPSRFRMTMLCSPGYPWVPGLQEHTPASALLFRESVKPRGARMEAEKTREQLENNRNSIYPPVPGQESSLQWAGMKFEEVPIAHIKATYNNTQIQVVSATNTSLARASCGTEGFRNAKKGTGIAAQTAG--IAAAAKATGKGVTHIRVVVKGIGPGRWSAIKGLTMGG-----LEVISITDNTPVPHNGCRPRKARRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCA2-1", "uniprot_id": "RT11_MOUSE", "id": "Q9DCA2-1", "name": "Small ribosomal subunit protein uS11m", "aln": "--MQVLRN-----SGSWLLLSWAGHGMT-RFVGIAPAKNIHTGAPRLEDSAARQNTEREAAPSRF----------------------------------------------------SLYPPVPGQESSLQWAGMKFEDVPIAHIKATYNNTQIQVVSATNASLARASCGTEGFRNAKKGTGIAAQTAG--IAAAAKATGKGVTHIRVVVKGMGPGRWSAIKGLTMGG-----LEVISITDNTPVPHNGCRPRKARRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P82912-1", "uniprot_id": "RT11_HUMAN", "id": "P82912-1", "name": "Small ribosomal subunit protein uS11m", "aln": "--MQAVRN-----AGSRFLRSWTWPQTAGRVVARTPAGTICTGARQLQDAAAKQKVEQNAAPSHT--------------------------------------------------KFSIYPPIPGEESSLRWAGKKFEEIPIAHIKASHNNTQIQVVSASNEPLAFASCGTEGFRNAKKGTGIAAQTAG--IAAAARAKQKGVIHIRVVVKGLGPGRLSAMHGLIMGG-----LEVISITDNTPIPHNGCRPRKARKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VEN6-1", "uniprot_id": "Q9VEN6_DROME", "id": "Q9VEN6-1", "name": "", "aln": "---MSLKS-----VFLSALRSITMPAVPLQTSRIHTSACWRKAEDRKEMLASLPAKDEGTVGEKTVDIDTLIN-----------------------------------------RKAKFFP--DASTANTLFNGIPFNELPICNIRVSPNNTIISVTDHKGVLRLIRSCGIEGFKNTRKGTNIAAQATA--VTISGKAIELGWKTVRVKVRGLGPGRMSAIKGLQMGG-----LNIVSITDNTHVSFNPPRPRKQRSL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42847-1", "uniprot_id": "RT18_YEAST", "id": "P42847-1", "name": "Small ribosomal subunit protein uS11m", "aln": "MLLQPVWKGCRWTQFVRPIRRWNSTGTNRGVPFSFKDISNQEDITNISYPSSSDSVLTKSNGSSEVYKPKEE-----------------------------------------VVKYILHGKFTKNNTHLTFSSVVEDKNFHKNKGLTYNDTMLYYLNLPQKVKISLSTGCLGFRKAARGEYEAAFQTSGRMFELIKEKNMLNKDIEVVMDDFGKGRAAFISALVGKEGASVVKKVVKISDATKLKFGGVRSPKMRRL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . . :: : . :. . : : . :. : : *:* : . * * **::: :* ** :. : : :.* : .:* ** : : .* :::.*:* * : .. *. * * *", "identical_positions": 21, "similar_positions": 47, "identity": "8.14%" }, { "cls_id": "homologset.agr.SGD:S000005252", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JXS2-1", "uniprot_id": "A0A0G2JXS2_RAT", "id": "A0A0G2JXS2-1", "name": "Protein KRI1 homolog", "aln": "-------------MPEPRAPATLKVNAAFAARYSRYREREELQRLKDRYGDRDD-GSDSSSESDSSDEHVEFDPQQERDFYRTLSLLKK-KDPRIYQKDATFYQRTAEASSSESEEES-AALGKQ---KKVQPMYLKDYERKVILEKEGKYVDEDNSDGESVDHRLQETATKSYIEEQRQLKESFRAFVEDSSDEDSAGEGGSGLLQKHTKSGEEKAQEDVDYLEWLKGQKEIDSSESLKELTHLKEYWNNPELDEGEQFLRDYILNKRYEEDEEEETE----EER--VLGPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSASVKTYPRSIASSVRRKDDRRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRQVTGNET-----LGLEEQDLEDDFDPAQHDQLMQKCFGDAFYGTVE-EEKPQFEEEEGLEDDWNWDTWGGPEQNG-------AWSQQE---LHCEDPDFNMDADYDPSQ------PRKKLRE---------APTSGKRKRKSPFAAAVGQEKPMFDP-GDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILSADDKELNRWCSLKKTCMYRSEQEEMQEQRAYSQKAQSVWKKRQIFKSLCQEEVEMP-------------------------TEATGKSP-SKASSQVQLPMPSAAGGKKPQAELSGAKEEE-------------------------LAHTPC-------------------------------PEKPASQKQKSKKARLLG-PTVTLGGHKFS---------------RQRLQAFGLN-------PKRLH----FRQLGRQ---------------RKKQQSHA----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDQ9-1", "uniprot_id": "KRI1_MOUSE", "id": "Q8VDQ9-1", "name": "Protein KRI1 homolog", "aln": "-------------MPEPRASGCLKVNAAFAARYSRYREREELQRLKDRYGDPDV-GGDSSSESDSSDEHVEFDPQQERDFYRTLSLLKK-KDPRIYQKDATFYQRTAEASSSESEEEPPAALGKQEKQQKQQPMYLKDYERKVILEKGGKYVDEDNSDGETVDHRLQETSTKSYVEEQKQLKESFRAFVEDSSDEDSAGEGGSGLLQKHTKSREEKAQEEVDYLEWLKGQKDMDSSESLKELTHLKEYWNNPGLDEGEQFLRDYILNKRYEEEEEEEEE----EEEEGAPGPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKARKQEELKQLKNLKRKEILAKLEKLRQATGNET-----LGLEEQDLEADFDPAQHDQLMQKCFGDAFYGTAE-EEKPQFEEEDGLEDDWNWDMWGGPEQDG-------AWSQQE---LHCEDPDFNMDADYDPSQ------PRKKLRE---------APTSGKRKRKSPFAAAVGQEKPMFDP-GDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILSADDKELNRWCSLKKTCMYRSEQEEMQEQRVYSQKAQNMWKKRQIFKSLCQEEMEMS-------------------------TEATGKSQ-SKASPQVQLPTPNGADQRTPQAETLVSKEEG-------------------------LAHTSC-------------------------------PEKPASQKQKSKKARLLG-PTVTLGGHKFS---------------RQRLQAFGLN-------PKRLH----FRQLGRQ---------------RKKQQSHS----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N9T8-1", "uniprot_id": "KRI1_HUMAN", "id": "Q8N9T8-1", "name": "Protein KRI1 homolog", "aln": "-------------MPEPRGSSQLRVNAAFAARYNRYREREELQRLKDRYGDRDS-SSDSSSESDSSDERVEFDPQQERDFYKTLSLLKK-KDPRIYQKDATFYNRT--ASSSDSEEDP-EALEKQ---KKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNEM-----LGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVE-EEKPQFEEEEGLEDDWNWDTWDGPEQEG-------DWSQQE---LHCEDPNFNMDADYDPSQ------PRKKKRE---------APLTGKKKRKSPFAAAVGQEKPVFEP-GDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDKELNRWCSLKKTCMYRSEQEELRDKRAYSQKAQNSWKKRQVFKSLCREEAETP-------------------------AEATGKPQRDEAGPQRQLPALDGS---LMGPESPPAQEEE-------------------------APVSPH-------------------------------KKPAPQKRRRAKKARLLG-PTVMLGGCEFS---------------RQRLQAFGLN-------PKRLH----FRQLGRQ---------------RRKQQGPKNSS-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DRJ4-1", "uniprot_id": "KRI1_DANRE", "id": "Q6DRJ4-1", "name": "Protein KRI1 homolog", "aln": "-------------------MSDLKINKKFAEKYEKYRQKEELQRLKDRYGDQEEENSSNSSESDSDDSEVELDPKLDRDFYRTLSLLKK-KDPKIYQKDAKFYTEET--SGSGSDEQP--STSKQ----SEKPMFLKDYERKVILERGGKYEDDDSADEEISAKMQERAASPTYIQEQKEIQESLRKFVQDSDDEDSDGDG--QFLTRRTKTQEEKDKEEADYVEWLKGQTELDEKEELKDMKYLRDYWNNPQLDEKESFLRDFMLNKGYMEEED--------EERIPTYNELMQDDVDDSEDEGESFLHKQEDFERHYNFRFEEPDAGKVKTYPRNIATSVRSKDDRRKRKREEVKERKEKEKEQKQQQLKELKNLKRAEIMDKLKKLQELTGNEQ-----LAFNDVDLDGDFDPQQHDQLMQKVFGDEYYEENE-EEKPQFEGDEEFEENWNWDTWVGKQQNEEEYDHKEDYTAEEHYQPNCDDPDFIMDADYDPSQQAVSKKKRKKEREEKKKKSKEDVPLMGKKRKKSHFAEIISKSKPVFDP-NEKSFEQYLDEYYKLDFEDIIDDLPCRFRYREVVANDFGLSTDEILNAGDKELNRWCSLRKTCMYRSEREELCDLKNFQIKARNVKKKQQVFVSLFNENDGQEEQKD------TKGKVGKKRRDRLKKAELTEKSDTTVTEETAEPPPAEQADVQDLKATIANDEEEDDEEFLVPKKKMKTAETVVTKRKEADVERTEK-------------------------------PKRPRKKMRRSGGRRLLKSMTVKMAGREFS---------------RQRLQAYGLN-------PKRLH----FRELYRQ---------------KRKEREKQEKQQKKSKQ-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTU0-1", "uniprot_id": "KRI1_DROME", "id": "Q9VTU0-1", "name": "Protein KRI1 homolog", "aln": "-----MNNNLFEGSDDDGEDLQLSTNKDYAKTYNILRKKELLQKYKDRGLDVSE--SEFDSDSSSSEE-DEVDPKFDQDFFKTLSSLKS-KDPCIYDKGTKFFSES---SGDEDDKDGEAPKKKK----KAKPVTLKDYERKVILEHNGKFESSDEEQQEKEHEELQRAQSPSAVEEERRLKAEFRKVMNKEDDSEDEEFG--GIFKKRSKTKEQTAAEEADFAKWLAGKQAEIQETDKKQLEPLKQYWSSNKLTQGESFLRDYILNKGYANTDES---------AIPTYDEIVGEAAPLSEDEQE--LEKQAEFEHKYNFRFEEPDADFIKRYPRTIEQSLRRTDDKRKEKRKELKERKDQEKQQKMKELELVKEMKRKEIDEKIRKLKAVTGNDE-----LGFRDEELEEDFDPAAHDRRMQELFDDEYYNVDEGEEKPECPSDIDELVLEDWDNYDPRQHAN---------GGGEDYEGHCEDDDFNMDCDYDPST------AKEQLQQELIEN---TRGRKGRKGRRNRFMEMIQAEKPAFNPEDEKTYSEYIDEYYQMDCEDIIGDQPCRFKYVETTPNDFGLTIEEILLAKNKELNQWASLKKAVQNRPEHVEKKEQRLYKMKAKNEDLKRKIFKSLYGEGSDDEEQPAEEKPEVTPAEATAPAENGQVSTEGLSKSKRKRLKRKAAAAAASAPKVLKEESDSKDPKEADGSTEDVQAESSKKKVDTPSKKGKDDANQETKNSPQSTEKTKNNNALKNNKKEPKNVQNGFQKPQNQANKSAKTKSNQPFKTTESAPAKAEKSNGNNPFNKPQSKSQQRQELPPIHKNQGGNKKGPRNANGTNPFKKSNQKPSAPFPAKKTNNFKAKNKQNNNSGITDDRLKAYGINPRKFHKREKYGKKDN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42846-1", "uniprot_id": "KRI1_YEAST", "id": "P42846-1", "name": "Protein KRI1", "aln": "MPRKKSAAKRAREQAKKEAAVPATDTATIKTSETSATTVKPAIEASKSYVPSEDEEEDEEEEEEEDDYGELITDEVENGINQVLDAIKNNKTDKLLDPKVKFFEDPESAAAKLANREG-----------KHKPIYLKDYHRMNILS--GDALKEDDEEYEHATVDGKQSFVSQQREEKTQLLNEIKSAFSDEENEESSGDEDDGFLKKKEPSTKKEGKN-----------------------------LPDPTVNE-ENFLEEFVNQQAWIPKKG---------------DKVISLDLNNNEEDDEEFEDAAEKFENAYNFRYEDPNAAEIISYARSQATLRRSDDSSRRRKREEKRKIKEQIKAEKETALQKKKTKKLNKLTDILEQLTKEYGAEINADMVKKITDTLLKNDFKEEEWDNVVAELFNEEFYQQEG---KPTWNEDDEIMGDFYADADGDDQTEE----------------GEVEKEQKEEDEEEGPKR------KKSKKEEK-------LQKKKEKRKVNELVENALEQNKLALIEEVEKEEEE------RKSRSRTKEEQDLKFRYREVSPESFGLTAREIFAADDTDLNEFIGLKKFAPYRSKELRAKDKRKVMKARRLREWRKKTFK-----------------------------------------------NENGLAPVEAEAGEKDEDTILIPVEKAS----------------------------KSK-------------------------------HKRGHSHKHKGHQKK------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . .. . . ..:....: . : :..: :.*. :*. * : : ..*: :.. :.: . :*: ****.* **. *. ..:. : * :.: :*: .: .:: .....:.:. :: :: : :: : . : : * **.::: :: : . . : ..:: * . .**. ****:*:*:: : *.*. * *. *:.**:* :: *.: * .* *: * * :: :.:* * : : : *. **. *. : : *.: :* ** : * : . :. : * : .*. :.: .: :: .. . : .* : :* .: : . . : :*:* . . .***: **: * :.:**.: .*:* *.:. . : : : ::: * . . . :: : .: : : ", "identical_positions": 70, "similar_positions": 191, "identity": "7.72%" }, { "cls_id": "homologset.agr.SGD:S000005254", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWJ1-1", "uniprot_id": "D3ZWJ1_RAT", "id": "D3ZWJ1-1", "name": "", "aln": "MQPNKMTSELSLLVGCASGVTPGGDRMQRAGGGWKLKRAASGRCAHFQNGGYSFSCTGRCKKRWPRIVVVTVPWNGMLRTALSRMPTLLRSVRTRDSGPRQLWDLGARLKTAKRL-RGWAWG----WRSSSSAPGSEHAAALG-------RVKADHYQLVYTCKVCGTRSSKHISKLAYHQGVVIVTCPGCQNHHIIADNLSWFSDLKGK----------RNIEEILAARGEEVRRVCGDGALELILEVAEPP---ATPEGGED--PTHPGKMDQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D113-1", "uniprot_id": "DNLZ_MOUSE", "id": "Q9D113-1", "name": "DNL-type zinc finger protein", "aln": "----------------------------------------------------------------------------MLRTALSRMPTLLRSVRTRDSGPRRLWDLGARLKTAERL-RGWAWGWASGWRSSSSAPGSGRAAALG-------RVEADHYQLVYTCKVCGTRSSKRISKLAYHQGVVIVTCPGCQNHHIIADNLSWFSDLKGK----------RNIEEILAARGEEVRRVSGDGALELILEAAVPP---DTPEGDED--PPNPGKMGQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SXM8-1", "uniprot_id": "DNLZ_HUMAN", "id": "Q5SXM8-1", "name": "DNL-type zinc finger protein", "aln": "----------------------------------------------------------------------------MLRTALRGAPRLLSRVQPRAPCLRRLWGRGARPEVAGRR-RAWAWG----WRRSSSEQGPGPAAALG-------RVEAAHYQLVYTCKVCGTRSSKRISKLAYHQGVVIVTCPGCQNHHIIADNLGWFSDLNGK----------RNIEEILTARGEQVHRVAGEGALELVLEAAGAPTSTAAPEAGEDEGPPSPGKTEPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L1P7-1", "uniprot_id": "DNLZ_DANRE", "id": "A1L1P7-1", "name": "DNL-type zinc finger protein", "aln": "---------------------------------------------------------------MNSRLCYLLFRPRLLRSRGAGVLSVPETQRVTLARVRHEESNSAFTNSTLRSDVGHDTG------LGLSFCRSFSTEAIG-------QLQSTHYHLVYTCKVCSTRSMKKISKLAYHKGVVIVTCPGCKNHHVIADNLKWFSDLEGK----------RNIEEILAAKGESVRRVEGSEALEIVNEESRNN-----PDEQKP--AHLSDGSDKT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXR1-1", "uniprot_id": "Q9VXR1_DROME", "id": "Q9VXR1-1", "name": "DNL-type domain-containing protein", "aln": "----------------------------------------------------------MSALKKFYKISAGVRRGALLTSSRRTQIDALNSPQLQLQVHHFATKTQTAVFSSSNNYTCICRSIHCSKPVDDADKTVATNSIPL-------AKLEAKMQLIYTCKVCQTRNMKTISKLAYQRGVVIVTCEGCSNHHLIADNLNWFTDLDGK----------RNIEEILAEKGEKVVRLT-DGNCEFLPKHD--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VXQ7-1", "uniprot_id": "Q9VXQ7_DROME", "id": "Q9VXQ7-1", "name": "DNL-type domain-containing protein", "aln": "-------------------------------------------------------MNALRNIFTSRTLNYLRQNGQNAILNATQQQQAVDAVPLTNDAEQHLKSSRPAPLSIPRSILDACHFTAKQFDLGGSTSGNQANGSLSPTTLKRFRRMQRRMELVYRCKLCNTRNTKTISEEAYYSGVVILQCDGCAVDHLIKDNLGLFTGSDGDSSISSGISTSKNIDQVLADRHARVRVIKVNERGELI------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42844-1", "uniprot_id": "ZIM17_YEAST", "id": "P42844-1", "name": "Mitochondrial protein import protein ZIM17", "aln": "-------------------------------------------------------------------MIPRTRTLLQSKIPITRYFARCWAPRVRYNVCRTLPAAALHTNIIAHN----------------EVKKDDKKVHLG-----SFKVDKPKMMIAFTCKKCNTRSSHTMSKQAYEKGTVLISCPHCKVRHLIADHLKIFHDHHVT------------VEQLMKANGEQVSQDVGDLEFEDIPDSLKDVLGKYAKNNSEN-ASQLPHPSQK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : : ** * **. : :*: ** *.*:: * * *:* *:* * . . ::::: . * . * : ", "identical_positions": 19, "similar_positions": 24, "identity": "6.88%" }, { "cls_id": "homologset.agr.SGD:S000005256", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63528-1", "uniprot_id": "RFA2_RAT", "id": "Q63528-1", "name": "Replication protein A 32 kDa subunit", "aln": "MWNSGFESFS--SSSYGAAGGYTQSPGGFGSPTPSQAEKKSRARAQHIVPCTISQLLSATL--TDEVFKIGDVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAAPMDVRQWVDTDDTSGENTVVP--------------PETYVKVAGHLRSFQNKKSLVAFKIIPLEDMNEFTAHILEVVNSHLMLSKANSQASVGR-PSMSNPGMGEPGNFSGNNFMPANGLTVVQNQVLNLIKACPRPEGLNFQD---LRSQLQHMPVASIKQAVDFLCNEGHIYSTVDDDHFKSTDAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62193-1", "uniprot_id": "RFA2_MOUSE", "id": "Q62193-1", "name": "Replication protein A 32 kDa subunit", "aln": "MWNSGFESFS--SSTYGGAGGYTQSPGGFGSPTPSQAEKKSRVRAQHIVPCTISQLLSATL--TDEVFRIGDVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAPPMDVRQWVDTDDASGENAVVP--------------PETYVKVAGHLRSFQNKKSLVAFKIIPLEDMNEFTAHILEVVNSHMMLSKPNSQASAGR-PSMSNPGMSEPGNFSGNNFMPANGLTVVQNQVLNLIKACPRPEGLNFQD---LRSQLQHMPVPSIKQAVDFLCNEGHIYSTVDDDHFKSTDAE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15927-1", "uniprot_id": "RFA2_HUMAN", "id": "P15927-1", "name": "Replication protein A 32 kDa subunit", "aln": "MWNSGFESYG--SSSYGGAGGYTQSPGGFGSPAPSQAEKKSRARAQHIVPCTISQLLSATL--VDEVFRIGNVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAAPMDVRQWVDTDDTSSENTVVP--------------PETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVINAHMVLSKANSQPSAGR-APISNPGMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQD---LKNQLKHMSVSSIKQAVDFLSNEGHIYSTVDDDHFKSTDAE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q13156-1", "uniprot_id": "RFA4_HUMAN", "id": "Q13156-1", "name": "Replication protein A 30 kDa subunit", "aln": "MSKSGFGSYGSISAADGASGGSDQ--LCERDATPAIKTQRPKVRIQDVVPCNVNQLLSSTV--FDPVFKVRGIIVSQVSIVGVIRGAEKASNHICYKIDDMTAKPIEARQWFGREKVK-QVTPLS--------------VGVYVKVFGILKCPTGTKSLEVLKIHVLEDMNEFTVHILETVNAHMMLDKARRDTTVES-VPVSPSEVNDAG---DNDESHRN---FIQDEVLRLIHECPHQEGKSIHE---LRAQLCDLSVKAIKEAIDYLTVEGHIYPTVDREHFKSAD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIH1-1", "uniprot_id": "Q9VIH1_DROME", "id": "Q9VIH1-1", "name": "", "aln": "-MNDSFGDFN--------------------ATQTAPTGAASNQKGEGIVPLVVKQIVDAP----EGNIELFGMQYAMACVVAIVRNVETSSTKITYTLEDHSGR-IDAHYWLE-EGDALKAPEVM--------------VNNYVKVYGTTRSQGGSKTLMIFKLLPVLDPNEVCTHLLEVLNARYRAEDYQSKGGAGAGAGASSGSGSIADFTASQSSAIVSGLEPKQQAVFQAIKSNVSEEGISRKE---LKAKFSHISDSELTNILDFMISEGHIYSSIDADHFICTM--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P26754-1", "uniprot_id": "RFA2_YEAST", "id": "P26754-1", "name": "Replication factor A protein 2", "aln": "--MATYQPYN--EYSSVTGGGFEN-----SESRPGSGESETNTRVNTLTPVTIKQILESKQDIQDGPFVSHNQELHHVCFVGVVRNITDHTANIFLTIEDGTGQ-IEVRKWSEDANDLAAGNDDSSGKGYGSQVAQQFEIGGYVKVFGALKEFGGKKNIQYAVIKPIDSFNEVLTHHLEVIKCHSIASGMMKQP------LESASNNNGQSLFVKDDNDTSSGSSPLQRILEFCKKQCEGKDANSFAVPIPLISQSLNLDETTVRNCCTTLTDQGFIYPTFDDNNFFAL---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. . .. .. : : :.* :.*::.: : : . . .*.::* . :* .::* :. ::.: * **** * : ..*.: : : . **. .* **.::.: . . * . . :. . * : : :. . * : .: : : : :*.**.:.* ::* . ", "identical_positions": 26, "similar_positions": 78, "identity": "8.9%" }, { "cls_id": "homologset.agr.SGD:S000005257", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P3X3-1", "uniprot_id": "TTC27_HUMAN", "id": "Q6P3X3-1", "name": "Tetratricopeptide repeat protein 27", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWTPELAILRGFPTEAERQQWKQEGVVGSESGSFLQLLLEGNYEAIFLNSMTQNIFNSTTTAEEKIDSYLEKQVVTFLDYSTDLDTTERQQLIFLLGVSSLQLFVQSNWTGPPVDLHPQDFLSSVLFQQFSEVKGLDAFVLSLLTLDGESIYSLTSKPILLLLARIILVN---------------------------------VRHKLTAIQSLP----------------------WWTLRCVNIHQHLLEE---------------------------------RSPLLFTLAENCIDQVMKLQNLFVDDSGRYLAIQFHLECAYVF--------------------------------LYYYEYRKAKDQLDIAKDIS---------------------------------------------------------------------------------------------------------------QLQIDLTGALGKRTRFQENYVAQLILDVRREGDVLSNCEFTPAPTPQEHLTKNLELN------------DDTILNDIKLADCEQ--------------------------FQMPDLCAEEIAIILGICTNFQKNNPVHT-LTEVELLAFTSCLLS----------------------------------------------------QPK--FWAIQTSALILR---------------------------------------TKLEKGSTRRVERAMRQTQALADQFEDKTT--------------------------------SVLERLKIFYCCQVPPHWAIQRQLASLLFELGCTSSALQIFEKLEMWEDVVICYERAGQHGKAEEILRQELEKKE-----------------------------------------TPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSKALLHLRNK--------------------------EFQECVECFERSVKINPMQLGVWFS--------------------LGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLK-------------------QKVKAFRTLQEALKCN-------------------YEH-WQIWENYILTSTDVGEFSEAIKAYHRLLDLR-----DKYKDVQVLKILVRAVIDGMTDRSGDVATGLKGKLQELFG-RVTSRVTNDGEIWRLYAHVYGNGQS-----EKPDENEKAFQCLSKAYKCDTQSNCWEKDITSFKEVVQRALGLAHVAIKCSKNKSSSQEAVQMLSSVRLNLRGLLSKAKQLFTDVATGEMSRELADDITAMDTLVTELQDLSNQFRNQY-----------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CD92-1", "uniprot_id": "TTC27_MOUSE", "id": "Q8CD92-1", "name": "Tetratricopeptide repeat protein 27", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGMMWTPELALLRGFSTEAERLVWKQEGICGSDIGVFLELLLEGSYEALFFHSTTQTILNSTMMAEEKIDSYLEKQIVNFLDCSTDLEEIERQQLVFLLGVSSLQLFVQSNWTGPLVDLHPQDFLPSGLLEQFSEVKGLDAIIMGLLILDGESVYSLTSKPILLLIARIILVN---------------------------------IRHKLTALQSLP----------------------WWTLRYVNIHQQLLEE---------------------------------RSPQLFALAKNCIDQVMKQENLFEGDSGRLLAIQFHLECAHVF--------------------------------LYYYEYKEAKDQFSTAKDIS---------------------------------------------------------------------------------------------------------------KLEIDLTGALGKRTRFQENYVAQLIVDVRRKEAVPFSCEFSPAPTPQECLAKNLELN------------DDTVLNEIKLADSER--------------------------FQMPDLCAEELAVVLGVCTNFQKNNPVHK-LTEEELLAFTSCLLS----------------------------------------------------QPK--FWAIQMSALILR---------------------------------------TKLERGSTRRVERAMRQTQALADQFEDKAT--------------------------------SVLERLKIFYCCQVPPHWAVQRQLAGLLFELGCTSSALQIFEKLEMWEDVVICHERAGRHGKAEEILRQELEKKE-----------------------------------------TPGLYCLLGDVLQDHSCYDKAWELSRHRSARAQRSKALLHLRNK--------------------------EFRECVECFERSVKINPMQLGVWFS--------------------LGCAYLALEDYGGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLK-------------------QKVKAFRTLQEALKCN-------------------YEH-WQIWENYILTSTDVGEFGEAIKAYHRLLDLR-----DKYKDIQVLKILVQAVVNDMTDRSGAVASSLKGKLQELFG-RITSRVTNDGEVWRLYAQVHGNGQS-----EKPDENDKAFQCLSKAYKCDTQSSCWEKDATAFKEVVQRAIGLAHVAMKCAESKSIPQEAVQTLSSVRLNLRGLLSKAKQNFTDVVSGEVSGELASEIAAVNALEAELQDLSNQLRNRY-----------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VVM8-1", "uniprot_id": "Q9VVM8_DROME", "id": "Q9VVM8-1", "name": "Tetratricopeptide repeat protein 27", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVADIFSEYYICNFNDAVTVEDLPAD-------ETLRQLWTRQKLWTIDELREILQRWQEHVKPDPNDNPTSQLKDFLLLIFA-----FVQNSFTGPFDKLEEYQQIHS-------ELELEKLDALEKLKASGEELNPNVKSVELLLIAREILEG---------------------------------LLENHPESKVLI----------------------WWRLRLICLHQHVLDD---------------------------------LAASLYEQFKSAAGHLQAHFNQFES---RELQSLLLLELANGY--------------------------------LQFHRSEIASQILDELCKHL---------------------------------------------------------------------------------------------------------------QVELKVEGLLGVRTKFQQKALPQLCLKVEHLNEQQP-LPPAVQTNETTKLPKLLLLE------------DDTRLERIRFVELKD--------------------------NEVMTLPSVLQALVLAKVKQLKRSTPKDR-LADEQLEPYTQTLLY----------------------------------------------------QEHG-PFQVRQSALLLN---------------------------------------CLQESNQRRTVERSWKQCEECVKLLDTSEEE------------------------------LSLRSRLSYGFAAHLSPKWQVQLQLVDLLRSLGMTKTALDICLRIHAWQQVIECYTSLELRHKAAEIIRQELEKKP-----------------------------------------TALLYCLLGDAIDDPSFYEQAWLYSKKTSGKAQAYWGNHFYRSA--------------------------DYAQAMDHFEISLEINNLQEAILLR--------------------CGYCAIQLERWEPAVKYYLAYTHLEPNGFESWNNLAKALIKLG-------------------DKQRAHRVLGEALKCN-------------------YSN-WKVWENYMLVSVDTSHWDDAMRAYQRMAELK-----QHYLDQEVLTRIVYGVSKEDPAGS----SALIKRLIKLLG-QQSIQHGNEPLVWELAALVAQTPLK-----KAEKLVKSYRAYTPKHLGWETKSEHALKALDLCLEVCD----LSVAAITEHIQEESEVMITSQLNSARLAGTSCLNALKRAINVDVSAEQTAKVEQLEKRIEDLTKIVQERMNASRS-------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42842-1", "uniprot_id": "EMW1_YEAST", "id": "P42842-1", "name": "Essential for maintenance of the cell wall protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METLLHAKLLLSAEVESLKSGSFDQTYVKKAEHIISGESYQLVQQFVDKFKGKISISGEISTSSVIAALNDFLN---VEVFKMGQENEMLFLAIALLQTFIQNNYTGPAARLKAISGLFG---KTGIEIGAVNTALSRSLAIMGQPAYEFMDDPLYLVLSLLLLER---------------------------------ITGQKSLFDVTPDQEIPLPIISAESTPGLLAVAYWWWARALLTQLSLIPEP--------------------------SGFQASVASAIYQSADLAYAITKELPESIHEDFKRELCAMYYLENVKCS--------------------------------LAINTEHLCLPSLTRAKKIT---------------------------------------------------------------------------------------------------------------NFEFVMTGARATRTKYQQKAHAGLIILAKSFTFQNFALRTTSATPETFALESDLLLEKPHFESIADEPLDEQIYSKRQKVDLNEGYEEDKLLPLALRQENIPKLLLDLNPNDQPTLSDYDNIQLLLRLYTIKNTTPAKDPLVEEELTALLSRILY----------------------------------------------------QNGDKNWSIFARSLWER---------------------------------------SIIETTKAKTIERGLLQMQSLVEELDLKIKSKLVPSSSE----------------------INVASRLSYIHQLPFIPRWQLDATLAEKYMSLGILKSAVEIYERLGMACETALCYAAVGDEKKAEEILLQRINENDS----------------------------------------DARAYSILGDIKQDPSLWEKSWEIGKYVNAKNSLAKYYFNPPPKSGAQP---------------------NYSATLKHLNDSLRQYPLSFETWYF--------------------YGCVGLQCGKMQIAAEAFTRCVSLDPYHALSWSNLSAAYTKMD-------------------KLKEAYSCLKRAISCD-------------------AQKNWKIWENYMLVAVKLNEWEDVLTACKQLVSIRRDKSGEGSIDLPIIEKLVELLVTSEYPEEPQQLSYFQKSCTEFICNTLPQVITTSARCWRLVARVELWRKRPW---AALECHEKAYRAISHNPDLEVEEKVWNDTVDACEDLVAAYESLGEMEGKYG---PGSLVCKDWKYKCRSTIKALMSKGKGRWDDSPGWDRLVEARSQI--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q00918-1", "uniprot_id": "LTBP1_RAT", "id": "Q00918-1", "name": "Latent-transforming growth factor beta-binding protein 1", "aln": "MAGAWLRWGLLLWAGLLAWSAHGRVRRITYVVRPGPGLPAGTLPLAGPPRTFNVALDARYSRSSTATSSRSLAGPPAERTRRTSQPGGAALPGLRSPLPPEPARPGAPSRQLHSKAGAQTAVTRFAKHGRQVVRSKVQQDTQSSGGSRLQVQQKQQLQGINVCGGQCCHGWSKAPGSQRCTKPSCVPPCQNGGMCLRPQFCVCKPGTKGKACEITAAQDTMSPVFGGQNPGSSWVPPEPAAKRTSTKKADTLPRVSPVAQMT-LTLKPKPSMGLSQQIHSQVAPLSSQNVMIRHGQTQEYVLKPKYFPAPKVVSGEQSTEGSFSLRYGQEQGTAPFQVSNHTGRIKVVFTPSICKVTCTKGNCHNSCQKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVLGASMPKLYQHAQQPGKALGSHVIHSTHTLPLTMTNQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPVGQRVKEVQPGQSQVSYQGLPVQKTQTVHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKQSYHGYTQMMECLQGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCSCKMGFGPDPTFSSCVPDPPMISEEKGPCYRLVSPGRQCMHPLSVHLTKQICCCSVGKAWGPQCEKCPLPGTAAFKEICPGGMGYTVSGIHRRRPIHQHIGKEAVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTSSREHGPGVAEPEVVTAPPEKEIPSLDQEKTRLEPGQPQLSPG------VSTIHLHPQFPVVVEKTSPPVPVEVAPEGSTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYKFSEQQRKCIDIDECAQAQHLCSQGRCENTEGSFLCICPAGFIASEEGSNCIDVDECLRPDVCRDGRCINTAGAFRCEYCDSGYRMSRRGHCEDIDECLTPSTCPEEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLQPKVCTNGSCTNLEGSYMCSCHKGYSPTPDHRHCQDIDECQQGNLCMNGQCKNTDGSFRCTCGQGYQLSAAKDQCEDIDECEHRHLCSHGQCRNTEGSFQCLCNQGYRASVLGDHCEDINECLEDSSVCQGGDCINTAGSYDCTCPDGLQLNDNKGCQDINECAQPGLCAPHGECLNTQGSFHCVCEQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRATEDSGVDRQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVQGTAEFSEMCPRGKGFVPAGESSYETGGENYKDADECLLFGEEICKNGYCLNTQPGYECYCKEGTYYD-PVKLQCFDMDECQDPNSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCVQPTESNEQIEETDVYQDLCWEHLSEEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPMKDSDDYAQLCNIPVTGRRRPYGRDALVDFSEQYGPETDPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDMAKMTCVDVNECSELNNRMSLCKNAKCINTEGSYKCVCLPGYVPSDKPNYCTPLNTALNLDKDSDLE", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : . : * .. ** : . . . : *. :::. . : . : : : . . . * : . : * *. .*. : : . . . : . . : : : : : ... :. :: . : : : .: . . ::. . . . .*. . : . : : : * . .* : : ::: . ** . :: : . . . . :: .:. . * : .. :: : : . ... * * *: . ::: : :.. .. . . : * : : . : : : .:.. . :: : * : ", "identical_positions": 19, "similar_positions": 137, "identity": "1.1%" }, { "cls_id": "homologset.agr.SGD:S000005259", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZY50-1", "uniprot_id": "D3ZY50_RAT", "id": "D3ZY50-1", "name": "", "aln": "MEQARGPGAEADAPEEEEGEAQEAMAAVVSAAGGACPAVLQVAGLYRGLCAVRSRALG--LGFVSPAQLRVFPVRRGSGLSSGGTDGGGV---SELETNPFYDRYRDKIQQLRRSDPAAFESRLEKRSEFRKQPVGHSKQSDFIRCVEQKTDALGKQP------------VSKGFTKDKTLSSVFNVEMVKDKTGEEIKQIWQQYFSAKD-TVYAVIPKEKFDVIWNRAQSCPTFLCALPRRD-----------GYEFFVGQWTGT-----ELHFTALINIQTRGDAAASQLILYHYPELKEEKGIVLMTAEMD-STFLNVAEAQCIANQVQLFYATDRKEI------YGLVETFNFRPNEFKYMSVIAELEQSGLGAELKCAQTQDKT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q811I0-1", "uniprot_id": "ATPF1_MOUSE", "id": "Q811I0-1", "name": "ATP synthase mitochondrial F1 complex assembly factor 1", "aln": "------------------------MAAVVSAAGGACPAVLQVAGLYRGLCAVRSRALG--LGFVSPAQLRVFPVRRGSGLPPEGADGSGV---SELEANPFYDRYRDKIQQLRRSDPAAFESRLEKRSEFRKQPVGHSKQSDFIKCMEQKTDALGKQP------------VSKGFTKDKTLSSVFNVEMVKDKTAEEIKQIWQQYFSAKD-TVYAVIPKEKFDLIWNRAQSCPTFLCALPRRD-----------GYEFFVGQWTGT-----ELHFTALINIQTRGDAAASQLILYHYPELKEEKGIVLMTAEMD-STFLNVVEAQCIANQVQLFYATDRKEI------YGLVETFNFRPNEFKYMSVIAELEQSGLGAELKRAQNQDKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TC12-1", "uniprot_id": "ATPF1_HUMAN", "id": "Q5TC12-1", "name": "ATP synthase mitochondrial F1 complex assembly factor 1", "aln": "-----------------------MAAVVVAAAGGAGPAVLQVAGLYRGLCAVRSRALG--LGLVSPAQLRVFPVRPGSGRPEGGADSSGVGAEAELQANPFYDRYRDKIQLLRRSDPAAFESRLEKRSEFRKQPVGHSRQGDFIKCVEQKTDALGKQS------------VNRGFTKDKTLSSIFNIEMVKEKTAEEIKQIWQQYFAAKD-TVYAVIPAEKFDLIWNRAQSCPTFLCALPRRE-----------GYEFFVGQWTGT-----ELHFTALINIQTRGEAAASQLILYHYPELKEEKGIVLMTAEMD-STFLNVAEAQCIANQVQLFYATDRKET------YGLVETFNLRPNEFKYMSVIAELEQSGLGAELKCAQNQNKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1L987-1", "uniprot_id": "ATPF1_DANRE", "id": "Q1L987-1", "name": "ATP synthase mitochondrial F1 complex assembly factor 1", "aln": "----------------------------MWDGEKMAAAMVQMSCLYRGMLAVRNHGIRPLIPGLVPSHFRAFSMKKEP----------------ELEENPYYSKYEEKIRKLRSSKPQEYESRLEKRTELKTEPLGRSRQAEFVKYMEKELDKRGKD-------------GDGGFTKDKTLGSILNLEMVQEKSGAEITELWMQYFSKKD-TISAVIPSSTFDVIFGRAKSCPTFLYALPQNE-----------GYEFFVGQWAGN-----ELHFTSLINVQTMGENAPSQLILYHYTDLQKDKDIVLMTAEMD-SKFVTVHQAQCLANQVQLFYGSQRLET------FRLVETFNHKPEEFKHMAVIAELEQSGIGPAVTTK------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VES8-1", "uniprot_id": "Q9VES8_DROME", "id": "Q9VES8-1", "name": "ATP synthase mitochondrial F1 complex assembly factor 1", "aln": "--------------------------------MACAKKLLFRVFLNNSLTANRTITMS----AARRAEEAIEKLK---------------------EDNPYYSKYASKIAKLQQTSAEEFLDRVERVVNPIKD--GQSQARSYSELLNPKQK---LQA------------EQAAELPHKKLTDIMKLELIEDKTAEEVSQIWLEYHKTKE-VLAATLSTSQYENLMARAKEHPVFLLPLPRSE-----------GFEFVMLQFAAN-----TVHFTPLLAYQVHHENAPECLTVVHYTEVQ-DKGVVLMRGEYD-TKVLTAQEAQCLANELQMFYLKPDEGK------LRLLNTFTRKPDEFKHMDLIKEVENIQLV------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32453-1", "uniprot_id": "ATP11_YEAST", "id": "P32453-1", "name": "Protein ATP11, mitochondrial", "aln": "-------------------------------MWRLTRKIGTRIHISNQLSPIFNKAIG------TVPVFRFYSSS---------------------PEQKYRKKLLEEAQKQGFNSIEELKNHLKETIESKKREFNKIDPLKELEDYQQKTQMENNNSKHLMTKSRSPLDPSAPKVPFKTLDSFLDVGKLKDLSKQEVEFLWRARWAQKDNTLCAVIPVSVYDKMMANARNNPIFVLPLPRQVQSEDAKPNEEQGMELHYIQWQFVGPQTTHCMMTSLAEYKLHQEFARPHTTLQFHSDLVKDKGIVFMNGHVEPDTNVNVQDAQLLLLNVQRFYGAMGEETPVAKQRVQLLRDFSKASPGFTVEKLISLSQSMEN-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : . . : . : : .: .: .. .:::. : . .: . . : : . : . *.* ..:.: ::: : *: :* *: .: *.:. . :: : .*:. * *: .**: * *: *: :*.* : : * : .:.:: :*.:*:* .. : . :.. :** : ::* ** *:. *. . *. :* :. ", "identical_positions": 29, "similar_positions": 95, "identity": "7.46%" }, { "cls_id": "homologset.agr.SGD:S000005261", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9C0J8-1", "uniprot_id": "WDR33_HUMAN", "id": "Q9C0J8-1", "name": "pre-mRNA 3' end processing protein WDR33", "aln": "----------------MATEIGS-PPRFFHMPRFQHQAPRQLFYKR----------PDFAQQQAMQQLTFDGKRMRKAVNRKTIDYNPSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLN-NPMNAVTTKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNVKMF-QAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLN-LNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWHVG--VEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSNDHTSKFWTRNRPGDKMRDRYNLNLLPG--MSEDGVEYDDLEPNSLAVIPGMGIPEQLKLAMEQEQMGKDESNEIEMTIPGLDWGMEEVMQKDQKKVPQKKVPYAKPIPAQFQQAWMQNKVPIPAPNEVLNDRKEDIKLEEKKKTQAEIEQEMATLQYTNPQLLEQLKIERLAQKQVEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFR---GRREESFR-RGAPPRHEGRAPP--RGRDGFPGPEDFGPEENFDASEEAARGRDLRG---RGRGTPRGG-RKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPR--PDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPKSG--RSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPPRRGASRGGGRGR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K4P0-1", "uniprot_id": "WDR33_MOUSE", "id": "Q8K4P0-1", "name": "pre-mRNA 3' end processing protein WDR33", "aln": "----------------MATEIGS-PPRFFHMPRFQHQAPRQLFYKR----------PDFAQQQAMQQLTFDGKRMRKAVNRKTIDYNPSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLN-NPMNAVTTKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNVKMF-QAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLN-LNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWHVG--VEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSNDHTSKFWTRNRPGDKMRDRYNLNLLPG--MSEDGVEYDDLEPNSLAVIPGMGIPEQLKLAMEQEQMGKDESSEIEMTIPGLDWGMEEVMQKDQKKVPQKKVPYAKPIPAQFQQAWMQNKVPIPAPNEVLNDRKEDIKLEEKKKTQAEIEQEMATLQYTNPQLLEQLKIERLAQKQADQIQPPPSSGTPLLGPQPFSGQGPISQIPQGFQQPHPSQQMPL-VPQMGPPGPQGQFRAPGPQGQMGPQGPPMHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPASQGHMGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPASQGIQG-----PLMGLNPRGMQGPPGPRENQGPAPQGLMIGHPPQEMRGPHPPSGLLGHGPQEMRGPQEMRGMQGPPPQGSMLGPPQELRGPSGSQGQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKAPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDTRGPPNHHLGPMSERRHEQSGGPEHGPDRGPFRGGQDCRGPPDRRGSHPDFPDDF-RPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFNEGDGRGAARGPPGAWEGRRPGDDRFPRDPDDPRFR---GRREESFR-RGAPPRHEGRAPP--RGRDNFPGPDDFGPEEGFDASDEAARGRDLRG---RGRGTPRGGSRKCLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDAPR--PDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGSGTSEHREMEAQGGPSEDRGSKGRGGPGPSQRVPKSG--RSSSLDGDHHDGYHRDEPFGGPPGSSSSSRGARSGSNWGRGSNMNSGPPRRGTSRGSGRGR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M1Z4-1", "uniprot_id": "A0ABK0M1Z4_RAT", "id": "A0ABK0M1Z4-1", "name": "pre-mRNA 3' end processing protein WDR33", "aln": "----------------MATEIGS-PPRFFHMPRFQHQAPRQLFYKR----------PDFAQQQAMQQLTFDGKRMRKAVNRKTIDYNPSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLN-NPMNAVTTKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNVKMF-QAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLN-LNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWHVG--VEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSNDHTSKFWTRNRPGDKMRDRYNLNLLPG--MSEDGVEYDDLEPNSLAVIPGMGIPEQLKLAMEQEQMGKDESNDIEMTIPGLDWGMEEVMQKDQKKVPQKKVPYAKPIPAQFQQAWMQNKVPIPAPNEVLNDRKEDIKLEEKKKTQAEIEQEMATLQYTNPQLLEQLKIERLAQKQADQIQPPPSSGTPLLGPQPFSGQGPMSQIPQGFQQPHPSQQMPL-VAQMGPPGPQGQFRAPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPAPQGHMGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPTSQGIQG-----PLMGLNPRGMQGPPGPRENQGPAPQGIMIGHPPQEMRGPHPPSGLLGHGPQEMRGPQEMRGMQGPPPQGSMLGPPQELRGPSGSQGQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKAPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKG-TKGRRERHASGLPSPPGLVATTTTSPFVVVTLEALPTITWAPCQRG---GMSRAVVLSMVLTGDLSGVARTAGVLLTGVALTLISLMTSADQMTSILTSALATGYGNSRDEEDPYHKKKSGGEGALDLPFHLITGSSMRGTAGVQPEALQGHGKAADLETNDSPGILMTHDFEGAEKKALEEVLPQDTKAVLLQEEGTTFLVLMTLVQKRFSMLLMKQPEDEISEVEAVAPLEGDPGSAYSPLLMSFLALKEDGSQTPGMETESPDQVMNTFVMLPVLIIPLTMAIHQLAESAPLLSKAWTWPPYHPGSAPGMMGRALLNTERWRPKEAPRRTEEAKAEGAQDLPREFQNPGVPALWTETIMMDTTEMNLLVALQAAAHLLEGAGVAVTGVEGVT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VNG2-1", "uniprot_id": "Q9VNG2_DROME", "id": "Q9VNG2-1", "name": "", "aln": "MDVSQPPPQLLTAPSALATNFTSLPPPNMGGQHYRHYHPHHGSNKHGYNQFKPFMPGGFQRPFGMSQDDFDGKRLRKSVMRKTVDYNASIIKALENRLYQRDYRDRLALQPDSIYVPHMLPPSAYLD-NPSNAVTTRFVKTATNKMRCPIFTLAWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDISVRTMVWSHNDSWMVTGDHGGYVKYWQSNMNNVKMY-QAHKEAIRGISFSPTDSKFVSGSDDGTLRIWDFMRCQEERVLRGHGADVKCVHWHPQKGMIVSGSKDNQQPIKIWDPKSGIALATLHAHKSTVMDLKWN-DNGNWLVTASRDHLLKLFDIRNLREEVQVFRGHKKEASSVSWHPIHEGLFCSGGSDGSILFWNVG--TDKEIGCVETAHDSIVWTLAWHPLGHILCSGSNDHTIKFWTRNRPGDLMRDKYNLNTLPASLAALDECEYDD------AIIPGMGPEDRVEFTES---LTADKG-----FIPGLDLDPSKAINDRDR---EKKVPYSKPIPRNFQVNWAG---PRRADDPSVLSIHEELAAREAKDTTNGLN---------HQQISENTMEGILASGMLNGLDPQTIVGVLVYN---------------RFIRVHPDSRLMA----------------------------AIRQGAEFLNKYIDAG-------KLEELNDVVPVRDRSRSVSPT--------------VEARGEMVS--------------PPTKKSRFEPR-----------------QHNAQLVCVR---------------ELMQCKKPFLQSLVAAKAQQ---PNTEFVDEPPLEQR----------DRDREREGDRDR----------------ERERARERERDQSGGRPNPWASNAPWSNNGNPG--GNGNGSNG-FSNNGAESFNDRDRGGGGQRRRRGINNSGPGNG--------GGSGGGG-------GGGSGRNRGRNNNRRY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42841-1", "uniprot_id": "PFS2_YEAST", "id": "P42841-1", "name": "Polyadenylation factor subunit 2", "aln": "-----------------------------------MDGHNQNQYQN----------------QNQIQQSQQPPLKKYVTQRRSVDVSSPYINLYYN---RRHGLPNLVVEPETSYTIDIMPPNAYRGRDRVINLPSKFTHLSSNKVKHVIPAIQWTPEGRRLVVATYSGEFSLWNASSFTFETLMQAHDSAVTTMKYSHDSDWMISGDADGMIKIWQPNFSMVKEIDAAHTESIRDMAFSSNDSKFVTCSDDNILKIWNFSNGKQERVLSGHHWDVKSCDWHPEMGLIASASKDN--LVKLWDPRSGNCISSILKFKHTVLKTRFQPTKGNLLMAISKDKSCRVFDIRYSMKELMCVR-DETDYMTLEWHPINESMFTLACYDGSLKHFDLLQNLNEPILTIPYAHDKCITSLSYNPVGHIFATAAKDRTIRFWTRARPIDPN--AYDDPTYNN------------------------------------------------KKINGWFFG----INNDINAVREKSEFGAAPPP------------PATLEPHALPNMNGFINKKPRQE----------------------------IPGIDSNIKSSTLPGLSI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :. * : : . *:::* ... *: * :*. .::*:: * .::** . . : :.::*.: ::**:: : .: *********..: ****:***. :*.***::**** .* :* :**:. **::.* .* :* **.*:. ** **.*:** :**..*.**.: ***. ::**:* . ::**:* ** ***. .*** *::.*.***. :*:***::* .:::: .* **:. : : :** *:: *:*: ::**** :*: .* .:.: :: ***::*.:* . ***: .:.: :: : : **: : :*:::*:***:.:.::*:* :**** ** * *: * * . ::. . :*. : * * * : . : : . :. . :.. . * : ", "identical_positions": 134, "similar_positions": 166, "identity": "9.66%" }, { "cls_id": "homologset.agr.SGD:S000005262", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P53403-1", "uniprot_id": "GTR3_DROME", "id": "P53403-1", "name": "Glucose transporter type 3", "aln": "-------MRKGGIQDAEPVEPPQSSRKSGTWFAKRPSEMPERHVERAPVRQKINNVGLYKATLYS---NIGSFFFGIAVGWSGTAERSVMEQHSY---------------SFQPTELQWSGVCILLTLGAALWCLPMGLMVRLLGCRRTILIQLLPNFLGWFLTVFAR-SVPMLYAGRFFLGMCGGAHCVVVPIYNAEISTTKKRGAMGVVFEGACICGVIYSFAMSLFLELRIINFVN------------LGLLALGPLQILMPESPAYYVDHG-NIPRAEDSLRFLRGQKYDTRREIDFLT------RDPTESEREVRQGPLLG-------FKYKKVRRSLARSLAIALLQKLCGALIFIFYGLNMLDCLRIRREFG--LILCLGLILGFLACFFLVDRLGRRPLLIFSSAGIVFVSIYLGLHFKVWMTMGLTVMSWIALFCIAIFVGCYTAGVGSLTWVLNAELLVRPMRPLGCSIVCAFNWLTAFFVICWFGSHGVKCQPYLFLLFAIIASLILLFSLIYIPETKKLSSAKIQQRLGGLINRPAVITFTSSSDSSNA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42833-1", "uniprot_id": "HXT14_YEAST", "id": "P42833-1", "name": "Hexose transporter HXT14", "aln": "MTAQIPYQHSSGYISHFHNNELDAGRGRDYNVTIKYLDDKEENIEGQAAKISHN-ASLHIPVLLCLVISLGGFIFGWDIGTIGGMTNMVSFQEKFGTTNIIHDDETIFVSTKKLTDLQIGLIISIFNISCGVGALTLSKIGDWIGRKGGIWFALVVYCIGITIQILSYGRWYFLTLGRAVTGIGVGVTTVLVPMFLSENSPLKIRGSMVSTYQLIVTFGILMGNILNFICERCYKDPTQNIAWQLPLFLGYIWAIIIGMSLVYVPESPQYLAKIKNDVPSAKYSFARMNGIPATDSMVIEFIDDLLENNYNNEETNNESKKQSLVKRNTFEFIMGKPKLWLRLIIGMMIMAFQQLSGINYFFYYGTSVFKGVGIKDPYITSIILSSVNFLSTILGIYYVEKWGHKTCLLYGSTNLLFYMMTYATVGTFGRETDFSNIVLIIVTCCFIFW--FAITLGPVTFVLVSELFPLRTRAISMAICTFINWMFNFLISLLTPMIVSKIDFKLGYIFAACLLALIIFSWILVPETRKKNEQEINKIFEPE------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..* . : ::.* . .: : : *.::* ..: . * ..*: ..* . .:*.*:** :* * . * *..: : : *:** . : ::.:...: .*.:. : :* : * : *: :* : ::: :* ** . *: *. *:**:: :* *. * **:* .:: *:: . :.:: * : .: : : :* : :**** * .. ::* *: *: :.* *:*: : *::.* :: .*: : *: * .: * :*:*.* *::** .::. : *: : :**. :*. : :: *:: *::. *::.*:.::* : . .. .:: : * : * ** :: :*.:*:** :**: *.:. :* :**: *:: * : * :** :::** * :***:* .. :*:: : ", "identical_positions": 99, "similar_positions": 181, "identity": "17.65%" }, { "cls_id": "homologset.agr.SGD:S000005264", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80UX8-1", "uniprot_id": "ABHDD_MOUSE", "id": "Q80UX8-1", "name": "Protein ABHD13", "aln": "MEKSWMLWSFIERWLLALASWSWALCRISLLPLIVTFHLYGGIVLLLLIFVSIAGILYKFQDVLLYFPEQPSSSRLYVPMPTG--IPHENIFIRTKDGVRLNLILVRYTGDNSPYCPTIIYFHGNAGNIGHRLPNALLMLVNLRVNLVLVDYRGYGKSEGEASEEGLYLDSEAVLDYVMTRPDLDKTKVFLFGRSLGGAVAIHLASENSH--RISAIMVENTFLSIPHMASTLFSFFPMRYLPLWCYKNKFLSYRKISQCR--MPSLFISGLSDQLIPPVMMKQLYELSPSRTKRLAIFPDGTHNDTWQCQGYFTALEQFIKEVIKSHSPEDMTKTSSNVTII------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A1B6-1", "uniprot_id": "D4A1B6_RAT", "id": "D4A1B6-1", "name": "Protein ABHD13", "aln": "MEKPWMLWSFIERWLLALVSWSWALCRISLLPLIVTFHLYGGIVLLLLIFVSIAGILYKFQDVLLYFPEQPSSSRLYVPMPTG--IPHENIFIRTKDGVRLNLILVRYTGDNSPYCPTIIYFHGNAGNIGHRLPNALLMLVNLKVNLVLVDYRGYGKSEGEASEEGLYLDSEAVLDYVMTRPDLDKTKVFLFGRSLGGAVAIHLASENSH--RISAIMVENTFLSIPHMASTLFSFFPMRYLPLWCYKNKFLSYRKISQCR--MPSLFISGLSDQLIPPVMMKQLYELSPSRTKRLAIFPDGTHNDTWQCQGYFTALEQFIKEVIKSHSPEDMTKTSSNVTII------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7L211-1", "uniprot_id": "ABHDD_HUMAN", "id": "Q7L211-1", "name": "Protein ABHD13", "aln": "MEKSWMLWNFVERWLIALASWSWALCRISLLPLIVTFHLYGGIILLLLIFISIAGILYKFQDVLLYFPEQPSSSRLYVPMPTG--IPHENIFIRTKDGIRLNLILIRYTGDNSPYSPTIIYFHGNAGNIGHRLPNALLMLVNLKVNLLLVDYRGYGKSEGEASEEGLYLDSEAVLDYVMTRPDLDKTKIFLFGRSLGGAVAIHLASENSH--RISAIMVENTFLSIPHMASTLFSFFPMRYLPLWCYKNKFLSYRKISQCR--MPSLFISGLSDQLIPPVMMKQLYELSPSRTKRLAIFPDGTHNDTWQCQGYFTALEQFIKEVVKSHSPEEMAKTSSNVTII------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q32LS6-1", "uniprot_id": "ABHDD_DANRE", "id": "Q32LS6-1", "name": "Protein ABHD13", "aln": "MEKPWRLWGPLEACLLSVCAWSWGFCRVSLLALILTFHLYGGFVLLGLILASLAGILYKFQDVLLYFPDQPSSSRLYVPMPTG--IPHENVYIRTKDGIRLNLILLRYTGENPAGAPTILYFHGNAGNIGHRVPNALLMLVNLKANVVLVDYRGYGKSEGDPSEDGLYQDAEATLDYVMTRPDIDKTKVVLFGRSLGGAVAIRLASCNPH--RVAAIMVENTFLSIPHMAATLFSFFPMRYLPLWCYKNKFLSYRHVVPCR--MPSLFISGLSDQLIPPVMMKQLYELSPSRTKRLAIFPEGTHNDTWQCQGYFSALEQFMKELLKSHAREETTQGTASVTII------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O76462-1", "uniprot_id": "O76462_DROME", "id": "O76462-1", "name": "", "aln": "MKEVGIALPKSRGVGVGVLA--------AFLLCFIFYYFYGGYMTLALFAGIILLIFYYAQDLLLYHPDLPANSRIYIPIPTMHNLPHITVSIKTPDDVTLHAFWVTQPEERSKSSPTLLYFHGNAGNMGHRMQNVWGIYHHLHCNVLMVEYRGYGLSTGVPTERGLVTDARAAIDYLHTRHDLDHSQLILFGRSLGGAVVVDVAADTVYGQKLMCAIVENTFSSIPEMAVELVHP-AVKYIPNLLFKNKYHSMSKIGKCS--VPFLFISGLADNLVPPRMMRALYTKCGSEIKRLLEFPGGSHNDTWIVDGYYQAIGGFLAELQQQPLLKAPEKSNVWVELEHKIIDV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42840-1", "uniprot_id": "YN60_YEAST", "id": "P42840-1", "name": "Uncharacterized membrane protein YNL320W", "aln": "------------------------------MLWKVSKMFLGGLVALTTIS---VATLYHYQNRLVY-PSWAQGARNHVDTPDSRGIPYEKLTLITQDHIKLEAWDIK----NENSTSTVLILCPNAGNIGYFILIIDIFYRQFGMSVFIYSYRGYGNSEGSPSEKGLKLDADCVISHLSTDSFHSKRKLVLYGRSLGGANALYIASKFRD--LCDGVILENTFLSIRKVIP---YIFPLLKRFTLLCHEIWNSEGLMGSCSSETPFLFLSGLKDEIVPPFHMRKLYETCPSSNKKIFEFPLGSHNDTIIQDGYWDIIRDFLIEKGFI----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : ** : * : :* *: *:* *. . .:* :: * :*: .: : * * : *. : . .*:: : ****:*: : : :: .:.: .***** * * .:* ** *: ..:.:: * .: ::.*:******* .: :*: ::**** ** .: .: :: : * : * * **:*** *:::** *: ** . * *:: ** *:**** :**: : *: * ", "identical_positions": 74, "similar_positions": 80, "identity": "21.2%" }, { "cls_id": "homologset.agr.SGD:S000005267", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAH8-1", "uniprot_id": "D4AAH8_RAT", "id": "D4AAH8-1", "name": "Cell cycle control protein", "aln": "-------------------------MEMVPQ---------------YDLSRLPENTALKQQTLPAQQLNLSASIVLSIFFATGGFCLSVGVILLLFAKSTKEIEINYTN--M-------------------------CANCAQLREDS--SNFDKECNCSLPLYLPEKMEGDVYMYYKLYGFYQNLYRYILSRSNSQLVG-----KDIWDTTN--CSPFQVSK-NDTPIIPCGAIANSIFNDTITLSYNLNSS--TQIEVPMLRSGLTWWTDKYVKFRNPRTSN---FTSTFAGSSKPLHWAKPVYELDLEDPGNNGFVNEDFIVWMRTAAFPTFRKLYRRLRREDS-FADGLPAGNYSLSISYNFPVTMFQGEKSVILSTLTWFGGGGLFLGLTYTVTGALTLLASFAILAVHLKLKRNKLSFL---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D4D7-1", "uniprot_id": "CC50C_MOUSE", "id": "Q9D4D7-1", "name": "Cell cycle control protein 50C", "aln": "-------------------------MEMMPQ---------------YDLSRLPENTALKQQTLPTQQLNLSASVVLSIFFITGGFCLSIGIILLLSAKSTKKIEINYTK--T-------------------------CANCAQLRENS--SNFDKACNCSLPFYLPEKMEGDVYMYYKLYGFYQNLYQYILSRSNSQLVG-----KDIWDTTN--CDPFQVSH-NDTPIIPCGAIANSIFNDTITLSYNLNSS--TQIEVPMLKSGLTWWTDKYVKFRNPRSSN---FTSTFAGSSKPLHWAKPIYELDLDDPGNNGFLNEDFIVWMRTAAFPTFKKLYRRLKRVHA-FAEGLPAGNYSLSISYNFPVTMFQGEKSIVLSTLTWIGGGGLFLGLTYTVTGALTLLASFAILTIHLMLKRSKLNFL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PHF1-1", "uniprot_id": "A0A8M1PHF1_DANRE", "id": "A0A8M1PHF1-1", "name": "Cell cycle control protein", "aln": "-----------------------MAKKAVGL---------------GPLSRRPDNSAFKQQRLPAWSPSLTAQTVLPIFYILAVVCLLLGIWLLITVQNTHQLKVDYTDAGT-------------------------CERCFELHAN----NTRTVCTCSVNFYVPRPFPGDVFFYYGLRNFHQNLRRYMDSRDDAQMVGR----KNNLKAPSSYCAPFHYDA-NGVPIAPCGAVANSMFNDSFTLMYHQANG--AEVQVPLYRKGIAWYTDKNVKFRNPPTNNTFSLRQAFEGTTRPLYWQHSVYELDDTDSNNNGFINDDLIVWMREAAFPNFKKLYGVLNRAQEPFTEGLPAGNYNISIDYNFPVEPFRGRKELVISMVTWFGGQNYFLPIAYLVTSGLILVTAVVLTTVFVKFGKNGKNMEE--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BHG3-1", "uniprot_id": "CC50B_MOUSE", "id": "Q8BHG3-1", "name": "Cell cycle control protein 50B", "aln": "-------------------------MTWSAT---------------ARGAHQPDNTAFTQQRLPAWQPLLSAGIALPLFFCAGLAFIGLGLGLFYSSNGIKELEYDYTGNPG-------------------------TGDCSVCAAKGQGRAPPPGCACSWSFTLPELFPGPVYLYYELSNFYQNNRRYGVSRDDAQLSGL----ASALRHPANECAPYQFRS-DGLPIAPCGAIANSLFNDSFSLWHQRQPSD-PFVEVPLDRTAIAWWTDYHVKFRNPPLVNG-SLALAFRGTAPPPNWHRPVYELSPDPN-NTGFINQDFVVWMRTAALPTFRKLYARIRQ--GNYSAGLPRGTYRVNITYNYPVRAFGGHKLIILSNISWMGGKNPFLGIAYLVVGSLCIVMGFVMLVVYIRYQDQDDDDNDDE------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z9E9-1", "uniprot_id": "D3Z9E9_RAT", "id": "D3Z9E9-1", "name": "Cell cycle control protein", "aln": "-------------------------MTWSAS---------------ARGAQQPDNTAFTQQRLPAWQPLLSAGITLPLFFCAGLAFIGLGLGLFYSSNGIQELEYDYTGNPG-------------------------TGNCSVCAAKGQDRAPPPSCQCSWSFTLPELFPGPVYLYYELSNFYQNNRRYGVSRDDAQLSGL----ASALRHPANECAPYQFSS-DGLPIAPCGAIANSLFNDSFSLWHQRQPAD-PFVEVPLDRTAIAWWTDYHVKFRNPPLVNG-SLALAFKGTAPPPNWHRPVYELSPDPN-NTGFINQDFVVWMRTAALPTFRKLYARIRQ--GNYSAGLPRGTYRVNITYNYPVRAFGGHKLIILSNISWMGGKNPFLGIAYLVVGSLCILMGFVMLVVYIRYQDQDDDDNDDE------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3MIR4-1", "uniprot_id": "CC50B_HUMAN", "id": "Q3MIR4-1", "name": "Cell cycle control protein 50B", "aln": "-------------------------MTWSAT---------------ARGAHQPDNTAFTQQRLPAWQPLLSASIALPLFFCAGLAFIGLGLGLYYSSNGIKELEYDYTGDPG-------------------------TGNCSVCAAAGQGRALPPPCSCAWYFSLPELFQGPVYLYYELTNFYQNNRRYGVSRDDAQLSGL----PSALRHPVNECAPYQRSA-AGLPIAPCGAIANSLFNDSFSLWHQRQPGG-PYVEVPLDRSGIAWWTDYHVKFRNPPLVNG-SLALAFQGTAPPPNWRRPVYELSPDPN-NTGFINQDFVVWMRTAALPTFRKLYARIRQ--GNYSAGLPRGAYRVNITYNYPVRAFGGHKLLIFSSISWMGGKNPFLGIAYLVVGSLCILTGFVMLVVYIRYQDQDDDDEE--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VEK0-1", "uniprot_id": "CC50A_MOUSE", "id": "Q8VEK0-1", "name": "Cell cycle control protein 50A", "aln": "-----------------------MAMNYSAKDEVD--GGPAGPPGGAAKTRRPDNTAFKQQRLPAWQPILTAGTVLPTFFIIGLIFIPIGIGIFVTSNNIREIEIDYTGTEP-------------------------SSPCNKCLS-----PNVTSCACTINFTLKQSFEGNVFMYYGLSNFYQNHRRYVKSRDDSQLNGD----PSALLNPSKECEPYRRN--EDRPIAPCGAIANSMFNDTLELYLVANESDPKPIPIPLKKKGIAWWTDKNVKFRNPPGKE--SLEEKFKDTIKPVNWHKAVYELDPEDESNNGFINEDFIVWMRTAALPTFRKLYRLIERR-DDLHPTLPAGQYFLNITYNYPVHSFDGRKRMILSTISWMGGKNPFLGIAYITIGSISFLLGVVLLVINHKYRNSSNTADITI------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AY41-1", "uniprot_id": "CC50A_RAT", "id": "Q6AY41-1", "name": "Cell cycle control protein 50A", "aln": "-----------------------MAMNYSAKDEVD--GGPTGPPGGAAKTRRPDNTAFKQQRLPAWQPILTAGTVLPTFFIIGLIFIPIGIGIFVTSNNIREIE------------------------------------------------------------------GNVFMYYGLSNFYQNHRRYVKSRDDSQLNGD----PSALLNPSKECEPYRRN--EDKPIAPCGAIANSMFNDTLELFLVANESDPKPVPILLKKKGIAWWTDKNVKFRNPPGKD--SLQEKFKDTTKPVNWHKPVYELDPDDESNNGFINEDFIVWMRTAALPTFRKLYRLIERT-DDLHPTLPAGQYYLNITYNYPVHFFDGRKRMILSTISWMGGKNPFLGIAYITIGSISFLLGVVLLVINHKYRNSSNTADITI------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NV96-1", "uniprot_id": "CC50A_HUMAN", "id": "Q9NV96-1", "name": "Cell cycle control protein 50A", "aln": "-----------------------MAMNYNAKDEVD--GGPPCAPGGTAKTRRPDNTAFKQQRLPAWQPILTAGTVLPIFFIIGLIFIPIGIGIFVTSNNIREIEIDYTGTEP-------------------------SSPCNKCLS-----PDVTPCFCTINFTLEKSFEGNVFMYYGLSNFYQNHRRYVKSRDDSQLNGD----SSALLNPSKECEPYRRN--EDKPIAPCGAIANSMFNDTLELFLIGNDS--YPIPIALKKKGIAWWTDKNVKFRNPPGGD--NLEERFKGTTKPVNWLKPVYMLDSDPD-NNGFINEDFIVWMRTAALPTFRKLYRLIERK-SDLHPTLPAGRYSLNVTYNYPVHYFDGRKRMILSTISWMGGKNPFLGIAYIAVGSISFLLGVVLLVINHKYRNSSNTADITI------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PEQ2-1", "uniprot_id": "A0A8M1PEQ2_DANRE", "id": "A0A8M1PEQ2-1", "name": "Cell cycle control protein", "aln": "----------------------MMASSYNAKEEDGHHSGTAGLGGTAIRTRKPDNTAFKQQRLPAWQPILTAGTVLPAFFVIGLIFIPIGIGLYVTSNNIKEFEIDYTGTDM-------------------------SSPCFNCSQS-FSWNSTTPCKCTLSFSLDQPFESNVFMYYGLSNFYQNHRRYVKSRDDSQLNGD----ERSLKEPSKECEPYRIN--DNKRIAPCGAIANSMFNDTLDLFYIDPNG--TKTQIPMIKKGIAWWTDKHVKFRNPGGNNP-NLTAVFIDTAKPINWRKPVYELDTDPE-NNGFINEDFIVWMRTAALPTFRKLYRIIQKK-NNMTPTLPRGNYSLEVTYNYPVRSFEGRKRMILSTISWMGGKNPFLGIAYITVGSICFFLGVVLLFIHHKYGNRNNSSDIPS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXG0-1", "uniprot_id": "Q9VXG0_DROME", "id": "Q9VXG0-1", "name": "", "aln": "------------------------MSTQQAENEES----------AAAKSKRPSDSAFKQQRLPAWQPVLTARTVLPTFFVIGVLFIPIGVVLLHLSNTANELIIDYTKCRR-------------------------SGGNTTCAEY-LEANPGVTCPCEVPFVLPSDFNGVVYMYYGLTNYYQNHRRYVKSRDDEQLLGH----LS--QTPSTDCAPFAYDPDSGKPIAPCGAIANSLFNDTLTLLQ-------GGSEIKLLKTGIAWPSDKRVKFRNP---EG-NLNVSLEGFSKPIFWQKGLADLDPENPDNNGFQNEDLIVWMRTAALPSFRKLYRRLNQTNTNYANGLKSGNYTLNIKYNYPVVSFDGTKRMILSTTSVLGGKNPFLGIAYIVVGAICITLGLALLFIHMRCSRSNMEMINVNPHTQYS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42838-1", "uniprot_id": "LEM3_YEAST", "id": "P42838-1", "name": "Phospholipid-transporting ATPase accessory subunit LEM3", "aln": "MVNFDLGQVGEVFRRKDKGAIVSGDNPEEEEDVDASEFEEDEVKPVRTKNRRPKEDAFTQQRLAAINPVLTPRTVLPLYLLIAVVFVIVGGCILAQNSKVDEVTIYYQDCMTNATSSWSDIPSEHWQFVFHKYKTYNTAPQWRFVDDESDDFTKQRGTCQIRFTTPSDMKNNVYLNYVLEKFAANHRRYVLSFSEDQIRGEDASYETVHDATGINCKPLSKNA-DGKIYYPCGLIANSMFNDTFPLQLTNVGD--TSNNYSLTNKGINWESDK-KRYKKTKYN--------YTQIAPPPYWEKMYPDGYNETNIPDIQDWEEFQNWMRPGAFDKITKLIRINKND------TLPAGEYQLDIGLHWPVLEFNGKKGIYLTHGSHLGGRNPFLGIVYLIGGCICAAMALILLTFWLFGGRKIADASSLSWNMK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.: *:.** *.: . *:. .*. : . : :* : . :. . *:: * * : * :* * .: *: * . * * . *** :***:***:: * : ...: * :* ::::. * * : ::: *** .*: .: ** .. * * * :.: ::** * * * : :: : :** . ** :.* . : .. : . ", "identical_positions": 51, "similar_positions": 74, "identity": "11.75%" }, { "cls_id": "homologset.agr.SGD:S000005269", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91WF7-1", "uniprot_id": "FIG4_MOUSE", "id": "Q91WF7-1", "name": "Polyphosphoinositide phosphatase", "aln": "------MPTAAAPIISS------------VQKLVLYETRARYFLVGSNHAETKYRVLKIDRTEPK-DLVVIDDRHVYTQQEVRELLGRLDLGNRTKMSQKGSSGLFRAVSAFGVVGFVRFLEGYYIVLITKRRKMADIGGHAIYKIEDTSMIYIPND-SVRISHPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEMLKSETSKACQESFDIFEDEGLITQGGSGVFGISSEPYMKYVWNGELLDIIKNTVHR--DWLLYIIHGFCGQSKLLIYGRPVYVTLIARRSSRFAGTRFLKRGANCEGDVANEVETEQILCDASVMSFT--------AGSYSSYVQVRGSVPLFWSQDISTMMPKPPITLDQADPFAHVAALHFDQMLQRFG-SPIIILNLVKEREKRKHERILSEELVAAVTYLNQFLPPEHTIVYIPWDMAKYTKSKLCNVLDRLNVIAESVVKKTGFFVNRPDSYCSILRPDEKWNELGGHVIPTGRLQTGILRTNCVDCLDRTNTAQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQDSINLFLGVFHPTEGK--PHLWELPTDFYLHHKNTMSLLPPRRSYTYWWTPEVVKHLPLPYDEVICAANLKKLMVKKFHRWEEEIDIHN----EFFRPYELSSFDDTFCLAMTSSARDFMPK-TVGIDPSPFTVRKPDETGKSVLGNKNTREEAVLQRKTAASAPPPPSEEAVSSSSEDDSGTDREDEGSISQRSTPVKMTDTGDSAKATENVVQP-MKEVYGVSLSSSLSEEDHSIYARFVQLGQSQHKQDRGNQQLCSRCSDGVIKLT------PISAFSQDNIYEVQPPRVDRKSTEIFQAHIQASQGIMQPLGKEDTAMYREYIRNRYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92562-1", "uniprot_id": "FIG4_HUMAN", "id": "Q92562-1", "name": "Polyphosphoinositide phosphatase", "aln": "------MPTAAAPIISS------------VQKLVLYETRARYFLVGSNNAETKYRVLKIDRTEPK-DLVIIDDRHVYTQQEVRELLGRLDLGNRTKMGQKGSSGLFRAVSAFGVVGFVRFLEGYYIVLITKRRKMADIGGHAIYKVEDTNMIYIPND-SVRVTHPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEMLKSEMTQNRQESFDIFEDEGLITQGGSGVFGICSEPYMKYVWNGELLDIIKSTVHR--DWLLYIIHGFCGQSKLLIYGRPVYVTLIARRSSKFAGTRFLKRGANCEGDVANEVETEQILCDASVMSFT--------AGSYSSYVQVRGSVPLYWSQDISTMMPKPPITLDQADPFAHVAALHFDQMFQRFG-SPIIILNLVKEREKRKHERILSEELVAAVTYLNQFLPPEHTIVYIPWDMAKYTKSKLCNVLDRLNVIAESVVKKTGFFVNRPDSYCSILRPDEKWNELGGCVIPTGRLQTGILRTNCVDCLDRTNTAQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQDSINLFLGVFHPTEGK--PHLWELPTDFYLHHKNTMRLLPTRRSYTYWWTPEVIKHLPLPYDEVICAVNLKKLIVKKFHKYEEEIDIHN----EFFRPYELSSFDDTFCLAMTSSARDFMPK-TVGIDPSPFTVRKPDETGKSVLGNKSNREEAVLQRKTAASAPPPPSEEAVSSSSEDDSGTDREEEGSVSQRSTPVKMTDAGDSAKVTENVVQP-MKELYGINLSDGLSEEDFSIYSRFVQLGQSQHKQDKNSQQPCSRCSDGVIKLT------PISAFSQDNIYEVQPPRVDRKSTEIFQAHIQASQGIMQPLGKEDSSMYREYIRNRYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VR06-1", "uniprot_id": "Q9VR06_DROME", "id": "Q9VR06-1", "name": "", "aln": "-MNNDNPNIVFNPLISS------------IQKVVLYETRARLYLVGSNNRETRFRLLTIDRLAHN-RLSIEENANEFNSLEIRRFVASL-------------SGSPKVTSAYGVLGFVRFLEGYYLLLVTKRKCCAHIGRHLVYTIKDTVMVRVNEVTSQRPPHPHEDRYKRMFQNIDLRSNFYFSYSYDLTRTLQYNESAPRYVGAKVDLDRDEPLPDWNTLTSNVDKAHERVD--YAFRSDSRKRFVWNAYLLQPMEGIMLK--DWLLEVTHGFVSQSCISIFGRHVNVCLVARRSSRFAGTRFLKRGANFQGDVANEVETEQIVSDG---------------QRICAFTQMRGSIPSHWSQDISKMVPKPQIQLDICDPYAQTPSLHFERLLFHYG-APLIMLNLVKKRERRKHESIISKELEYSIRYLNQFLPPPHRMKHIHFDMARQSRLSGGNVMEQLAIHAESIVQMTGMFFKAAGS------------EPG--------LQTGIVRTNCVDCLDRTNSAQFAIGKCALGHQLERLGFVKSAKLEFDSDCVTMLENLYEEHGDTLALQYGGSQLVHRIKTYRKTAPWGSQGSDVMQTLSRYYSNTFSDTEKQHSINLFLGIYKPSLTKQGPPIWELQTDYDMH--NAFVPRADSKAITDWVRHKVRACLPYSCAD---SNKLVKELFRVHSSGLEMIDAYS----NYHQSFKWTDFSEHIAFEISQLALRYMP--TFRTNFSPFQR--------QIQTSRKARQNPSMTGQSSTGSMNSNSS---SSSEGDDSSSD--EELSASFAEKEANQTESTEPAAATLATGLPSMEEIYGCTINP-PSKQSMAVYKKYVQMGKLSSGGARPAQTAVAQRDQELAKIMRGITLRPLSDYGTDSYLSVRPPVVPRKSLTIYAEYCRTRSTFNAVPKLEEFDVLYQYVQKL--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42837-1", "uniprot_id": "FIG4_YEAST", "id": "P42837-1", "name": "Polyphosphoinositide phosphatase", "aln": "MNNDAMEHTLGGGILTTSGSKQRKTSKFVMGKYTLYETKDRMYIVGSNKRETMFRILEIDLTVPRGELTVLEDNVFFTRNEIMNVLASLEEAT--------EDGLHKKITGYGLLGFIKFTCWYYLIMVTKYSQVAVIGGHGIYHIDGIDIIPITNNYKKPEKSSDEARLLNIFKDLDLTKTFYFSYTYDITNTLQTNILREKLKAVDR-CDITIPCG----------------------ITDYNEMFVWNNNLLSPIFACIDTVFDWFQCIIHGFIDQVNVSVLGKSIYITLIARRSHHFAGARFLKRGVNNKGHVANEVETEQIVTDMILTPFHQPGNGFFDSDRYTSFVQHRGSIPLYWTQDASNLTTKPPIRINVVDPFFSPAALHFDNLFQRYGGGTIQILNLIKTKEKTPRETKLLWEFEQCIDYLNEFLPTLKKLDYTSWDMSRASKQDGQGVIEFLEKYAVNTVTTTGIFHNGPDFAS-------------------TKIQEGICRSNCIDCLDRTNAAQFVIGKRALGCQLKSLGIIDNSYLEYDSDIVNILTELFHDLGDTIALQYGGSHLVNTMETYRKINQWSSHSRDMIESIKRFYSNSFVDAQRQDAINLFLGHYSWREGF--PSLWEMNTDFYLH--NAYSLNMPKRSYIHWWNDYNIKSVKELINEELIATGNDVTREKIIKNVRGYPGAFDNYWNEYYLPRSVTWIRDLFAYNMNSTRRYHNALSKQDKAMSPFTSRK-----QSWLNNKLKMITSSKSLEKAEGRVVETTDLDRDTSPKQE--LELYEHYLHIISDRSQKLEEKMNSFSYSKYPIFISHESSEIPPMRKVIGEPLVDIAEDFTDVYDDDDDGDDENDEMTTEALLIAPDHVS---------VDEKFYEKVLNVDDYKPALDDYSAVIHIKPDNLQLYRDLCFSKDIQLDFQ---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::: : * .****: * ::****: ** :*:* ** . * : :: :. *: ..:. * .* : :.:*::**::* **::::** * ** * :* :.. :: : : . ..* * .:*:::** ..*****:**::.:** * : : :: :*** **. : : **: : *** .* : : *: : : *:**** :***:******.* :*.**********: * ::.* ***:* .*:** *.: .** * :: **: .:***:.:: ::* ..: :***:* :*: :* : *: .: ***:***. : : : :**:: :: . .*:: * * . * **:* : .. :* ** *:**:*******:*** :** **. ** **::... *::*:* * :: :*:.: ***::******:**: ::**** * .:. *:::::.*:***:* *:::*.:****** : * :**: **: :* *: :: * : : : : . .. ::. . . : : : :. :.. . . . *** . .: . :.: . :. .:* :: : :. . : : :. : :. : .: : :.:: . . : :. . . . .* : : : : : : ", "identical_positions": 199, "similar_positions": 254, "identity": "20.9%" }, { "cls_id": "homologset.agr.SGD:S000005270", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59267-1", "uniprot_id": "ZDHC2_MOUSE", "id": "P59267-1", "name": "Palmitoyltransferase ZDHHC2", "aln": "-----------------------------------------------------------MAPSGSGG---VRRRCRRVLYWIPVVFISLLLGWSYYAYAIQLCIVSMENIGEQ---VVCLMAYHLLFAMFVWSYWKTIFTLPMNPSKEFHLSYAEKELLEREPRGEAHQEVLRRAAKDLPIYTRTMSGAIRYCDRCQLIKPDRCHHCSVCDKCILKMDHHCPWVNNCVGFSNYKFFLLFLAYSLLYCLFIAATDLQYFIRFWT------------NGLPDTQ--------AKFHIMFLFFAAAMFSVSLSSLFGYHCWLVSKNKSTLEAFRNPVFRHG-TDKNG-----------FSLG-FSKNMRQVFGDEKKYWLLPVFSSQGDGCSFPTCLVNQDPEQPS------TPAGLNSTVKNP-ENHQFPAKPLRESQSHLLKDSQTWTESSANPGKGKAGMSNP-ALTMENET-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JKR5-1", "uniprot_id": "ZDHC2_RAT", "id": "Q9JKR5-1", "name": "Palmitoyltransferase ZDHHC2", "aln": "-----------------------------------------------------------MAPSGPGG---VRRRCRRVLYWIPVVFISLLLGWSYYAYAIQLCIVSMENIGEQ---VVCLMAYHLLFAMFVWSYWKTIFTLPMNPSKEFHLSYAEKELLEREPRGEAHQEVLRRAAKDLPIYTRTMSGAIRYCDRCRLIKPDRCHHCSVCDKCILKMDHHCPWVNNCVGFSNYKFFLLFLAYSLLYCLFIAATDLQYFIRFWT------------NGLPDTQ--------AKFHIMFLFFAAAMFSVSLSSLFGYHCWLVSKNKSTLEAFRNPVFRHG-TDKNG-----------FSLG-FSKNMRQVFGDEKKYWLLPIFSSQGDGCSFPTCLVNQDPEQPS------TPAGLNSTAKNP-ENHQFPAKPLRESQSHLLTDSQTWTENSSNSGRCKAGMSNP-ALTMENET-------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UIJ5-1", "uniprot_id": "ZDHC2_HUMAN", "id": "Q9UIJ5-1", "name": "Palmitoyltransferase ZDHHC2", "aln": "-----------------------------------------------------------MAPSGPGSS--ARRRCRRVLYWIPVVFITLLLGWSYYAYAIQLCIVSMENTGEQ---VVCLMAYHLLFAMFVWSYWKTIFTLPMNPSKEFHLSYAEKDLLEREPRGEAHQEVLRRAAKDLPIYTRTMSGAIRYCDRCQLIKPDRCHHCSVCDKCILKMDHHCPWVNNCVGFSNYKFFLLFLAYSLLYCLFIAATDLQYFIKFWT------------NGLPDTQ--------AKFHIMFLFFAAAMFSVSLSSLFGYHCWLVSKNKSTLEAFRSPVFRHG-TDKNG-----------FSLG-FSKNMRQVFGDEKKYWLLPIFSSLGDGCSFPTCLVNQDPEQAS------TPAGLNSTAKNL-ENHQFPAKPLRESQSHLLTDSQSWTESSINPGKCKAGMSNP-ALTMENET-------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5BLG4-1", "uniprot_id": "ZDHC2_DANRE", "id": "Q5BLG4-1", "name": "Palmitoyltransferase ZDHHC2", "aln": "-----------------------------------------------------------MAPSGSRS-----FDCWRVLYWIPVLFISLIVAWSYYAYVVQLCIETIENMGEK---TVYLLIYHLLFLMFVWSYWQTIYSKPMNPLKEFHLSHVDKELLEREDRRESQQEILRRIAKDLPIYTRTMSGAIRYCDRCLLLKPDRCHHCSACDMCILKMDHHCPWVNNCVGFANYKFFMLFLAYSLLYCLFVTATDMQYFIQFWT------------NGLPDTQ--------AKFHIMFLFFAASTFSVSLAFLFAYHCWLVCKNRSTLEAFRAPAFQHG-TDKNG-----------FSLG-AYKNFRQVFGDEKKYWLLPIFSSLGDGCSFPTCLVNPDPEQPS------IPPGRNPSVKSAGESHPFPPKPLRESQSRLLNNGQ--TDGSED--RDKRGTSNP-ALTIEKET-------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB13ABL5-1", "uniprot_id": "A0AB13ABL5_DANRE", "id": "A0AB13ABL5-1", "name": "Palmitoyltransferase", "aln": "---------------------MQRRSFTGGAGGERMSGSHPSLP------VFCSQGRRKMAPTHVLR------CCQRGLAWIPVIFIALVVCWSYYAYVVELCLLTISSTGEK---IVYLVVFHLSFVMFVWSYWKTIFTKPANPSKEFCLPKSEKEQYEKEQRPETQQEILKKVATSLPLYTRTGAGAIRYCDRCQVIKPDRCHHCSACDMCVLKMDHHCPWVNNCVGFSNYKFFILFLTYSLVYCLFIAASVLQYFIKFWTLCRRKSAENCPKSDLPESH--------AKFHVLFLFFVAAMFCISILSLFTYHLWLVGKNRSTIEAFRAPVFRNG-PDKNG-----------FSLG-FSKNIAQVFGDEKKYWLLPVFTSQGDGLSFPTRLVTIDPEQPTECL---QPGGLDKGAVEVSAEQTS---PLSESQNRLLGNDYHSEEDHKETEVLKSDESEAITISIESES-------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1Q7H8-1", "uniprot_id": "ZD20A_DANRE", "id": "F1Q7H8-1", "name": "Palmitoyltransferase ZDHHC20-A", "aln": "-----------------------------------------------------------MAPSHAVR------CCQRGLSWIPVIFINLVVCWSYYAYVVELCIYTIPNVNEQ---VIYLVVFHAFFFMFMWSYWKTISSKPTNPSKEFCLPKAEKELYEKEERPEAQQDILKRVARELPIYTFTGSGAIRYCDRCQLIKPDRCHHCSTCDKCVLKMDHHCPWVNNCVGFSNYKFFVLFLAYSMLYCVYIAATVLQYFIKFWT------------NQLPDTH--------AKFHVLFLFFVAAMFFISILSLFSYHLWLVGKNRTTIEAFRAPVFRNG-PDKNG-----------FTLG-FRKNITQVFGDQKKYWCLPIFSSLGDGYTFPTRLVTVDVEH----------GNIEHQTIKCTVDGQTNARPLSESQNHLLCND----EGQKDSSMAAIEVCQPVCVTLENES-------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5Y5T1-1", "uniprot_id": "ZDH20_MOUSE", "id": "Q5Y5T1-1", "name": "Palmitoyltransferase ZDHHC20", "aln": "-----------------------------------------------------------MAPWTLWR------CCQRVVGWVPVLFITFVVVWSYYAYVVELCVSTISRTGEKGKTVVYLVAFHLFFVMFVWSYWMTIFTSPASPSKEFYLSNSEKERYEKEFSQERQQDILRRAARDLPIYTTSASKAIRYCEKCQLIKPDRAHHCSACDRCVLKMDHHCPWVNNCVGFTNYKFFMLFLLYSLLYCLFVAATVLEYFIKFWTLCRRKSTENCPKNEPTVLNFP-----SAKFHVLFLFFVSAMFFVSVLSLFSYHCWLVGKNRTTIESFRAPMFSYG-IDGNG-----------FSLG-CSKNWRQVFGDEKKYWLVPIFSSLGDGCSFPARLVGMDPEQAS-------VANQSDYVRSIGSNQPFPIKPLSESKNRLLDSESQWLENGAEEGVTKSGTNNHVTVEIEN---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PT74-1", "uniprot_id": "E9PT74_RAT", "id": "E9PT74-1", "name": "Palmitoyltransferase", "aln": "MLGGDGPGPGARRGGVAASPFATARGSRASGAGEVVTEPQGSWGPAEPWAAGLGNQQKNMAPWTLWR------CCQRVVGWVPVLFITFVVVWSYYAYVVELCVSTVSRTGEKGKTVVYLVAFHLFFVMFVWSYWMTIFTSPASPSKEFYLSNSEKERYEKEFSQERQQDILRRAARDLPVYTTSASKAIRYCEKCQLIKPDRAHHCSACDRCVLKMDHHCPWVNNCVGFTNYKFFMLFLLYSLLYCLFVAATVLEYFIKFWTLCRRKSTENCPKNEPTVLTFPSAKFPSAKFHVLFLFFVSAMFFVSVLSLFSYHCWLVGKNRTTIESFRAPMFSYG-IDGNG-----------FSLG-CSKNWRQVFGDEKKYWLVPIFSSLGDGCSFPTRLVGMDPEQAS-------IANQGEYIRSIGSNQPFPIKPLSESKNRLLDSESQWLENGAEEGITKSGTNNHVTVAIEN---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5W0Z9-1", "uniprot_id": "ZDH20_HUMAN", "id": "Q5W0Z9-1", "name": "Palmitoyltransferase ZDHHC20", "aln": "-----------------------------------------------------------MAPWTLWR------CCQRVVGWVPVLFITFVVVWSYYAYVVELCVFTIFGNEENGKTVVYLVAFHLFFVMFVWSYWMTIFTSPASPSKEFYLSNSEKERYEKEFSQERQQEILRRAARALPIYTTSASKTIRYCEKCQLIKPDRAHHCSACDSCILKMDHHCPWVNNCVGFSNYKFFLLFLLYSLLYCLFVAATVLEYFIKFWT------------NELTDTR--------AKFHVLFLFFVSAMFFISVLSLFSYHCWLVGKNRTTIESFRAPTFSYG-PDGNG-----------FSLG-CSKNWRQVFGDEKKYWLLPIFSSLGDGCSFPTRLVGMDPEQAS-------VTNQNEYARSSGSNQPFPIKPLSESKNRLLDSESQWLENGAEEGIVKSGTNNHVTVAIEN---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BGJ0-1", "uniprot_id": "ZDH15_MOUSE", "id": "Q8BGJ0-1", "name": "Palmitoyltransferase ZDHHC15", "aln": "-----------------------------------------------------MRRGWKMALSGGLR------CCRRVLSWVPVLVIVLVVLWSYYAYVFELCLVTVLSPAEK---VIYLILYHAIFVFFAWTYWKSIFTLPQQPNQKFHLSYTDKERYKNEERPEVQKQMLVDMAKKLPVYTRTGSGAVRFCDRCHLIKPDRCHHCSVCAMCVLKMDHHCPWVNNCIGFSNYKFFLQFLAYSVLYCLYIATTVFSYFIKYWR------------GELPSVR--------SKFHVLFLLFVACMFFVSLVILFGYHCWLVSRNKTTLEAFCTPVFTSG-PEKNG-----------FNLG-FIKNIQQVFGDNKKFWLIPIGSSPGDGHSFPMRSMN-------------------------------------ESQNPLLANEEPWEDNEDDSRDYPEG---SSSLAVESET-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2TGJ4-1", "uniprot_id": "ZDH15_RAT", "id": "Q2TGJ4-1", "name": "Palmitoyltransferase ZDHHC15", "aln": "-----------------------------------------------------MRRGWKMALSGGLR------CCRRVLSWVPVLVIVLVVLWSYYAYVFELCLVTVLSPAEK---VIYLILYHAIFVFFAWTYWKSIFTLPQQPNQKFHLSYTDKERYKNEERPEVQKQMLVDMAKKLPVYTRTGNGAVRFCDRCHLIKPDRCHHCSVCAMCVLKMDHHCPWVNNCIGFSNYKFFLQFLAYSVLYCLYIATTVFSYFIKYWR------------GELPSVR--------SKFHVLFLLFVACMFFVSLVILFGYHCWLVSRNKTTLEAFCTPVFTSG-PEKNG-----------FNLG-FIKNIQQVFGDNKKFWLIPIGSSPGDGHSFPMRSMN-------------------------------------ESQNPLLANEEPWEDNEDESQDYPEG---LSSLAVESET-------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96MV8-1", "uniprot_id": "ZDH15_HUMAN", "id": "Q96MV8-1", "name": "Palmitoyltransferase ZDHHC15", "aln": "-----------------------------------------------------MRRGWKMALSGGLR------CCRRVLSWVPVLVIVLVVLWSYYAYVFELCLVTVLSPAEK---VIYLILYHAIFVFFTWTYWKSIFTLPQQPNQKFHLSYTDKERYENEERPEVQKQMLVDMAKKLPVYTRTGSGAVRFCDRCHLIKPDRCHHCSVCAMCVLKMDHHCPWVNNCIGFSNYKFFLQFLAYSVLYCLYIATTVFSYFIKYWR------------GELPSVR--------SKFHVLFLLFVACMFFVSLVILFGYHCWLVSRNKTTLEAFCTPVFTSG-PEKNG-----------FNLG-FIKNIQQVFGDKKKFWLIPIGSSPGDGHSFPMRSMN-------------------------------------ESQNPLLANEETWEDNEDDNQDYPEG---SSSLAVETET-------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4LF16-1", "uniprot_id": "A0A0B4LF16_DROME", "id": "A0A0B4LF16-1", "name": "Palmitoyltransferase", "aln": "-----------------------------------------------------------MGNDDHRRRKTPCGFCMAVFKWIPVLFITAVIAWSYYAYVVELCIRNSENRIGM---IFMLLFYHLFLTLFMWSYWRTIMTSVGRIPDQWRIPDEEVSRLFRADSPDTQKRILNNFARDLPVTNRTMNGSVRFCEKCKIIKPDRAHHCSVCSCCVLKMDHHCPWVNNCVNFYNYKYFVLFLGYALVYCLYVAFTSLHDFVEFWKVGAYDNNGYSAQGQLNASGMG-------RFHILFLFFIAIMFAISLVSLFGYHIYLVLVNRTTLESFRAPIFRVGGPDKNG-----------YNLG-RYANFCEVFGDDWQYWFLPVFSSRGDGYSYPTSSDQSRVSTSSPTQRYDAMGDTTTSRLDGNPTDKLIGASPLDTTNHHHNQSPHQVRSTSVLPTQLLQIQPPSTCRDELNERQQKLANGQSLDCSTPAAMSSPDERGVNGAAVYIEMIGDHPLTSADPAKGFPRPPNGDLPV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1ZAR2-1", "uniprot_id": "A1ZAR2_DROME", "id": "A1ZAR2-1", "name": "Palmitoyltransferase", "aln": "-----------------------------------------------------------MCPIGEGHRRVPC----CAVRWLPALIILGFLVWSYHVFVYQICIKKVSDYLTI---GLLLFFYHLLLFMFLWTWFRCIFVAPVRIPDQWKISPEDVDKLKRNDGIEGASRVLNYAARNLPIATCTIDGLVRYCKTCWIIKPDRAHHCRTCHMCVLKMDHHCPWIVNCVHFHNFKYFILFLFYAEVYCFYLFCVMVYD---LYLICGFEVTALKNQHSWNILQY--------LVCILFNIFTVIMYTVSLLNVS--------RNRTTMESAYATYFLLGGKNNNG-----------FNLG-YFVNFRDLYGDKWYLWPFPIFSSRGDGFSFPLAHDR---------------------------------LKEVRTGNQKKDNQPTRTQMYKENMNRILGIHQP-----PFNEE------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42836-1", "uniprot_id": "PFA3_YEAST", "id": "P42836-1", "name": "Palmitoyltransferase PFA3", "aln": "-----------------------------------------------------------MNDRLSLT------------SLFPRCLTTCLYIWTAYITLTRIHQIPR---------WFLALTIVPTLAVALYTYYKVIARGPGSP-------LDFPDLLVHDLKAAENGLELPPEYMSKRCLTLKHDGRFRVCQVCHVWKPDRCHHCSSCDVCILKMDHHCPWFAECTGFRNQKFFIQFLMYTTLYAFLVLIYTCYELGTWFN-----------SGSFNREL--------IDFHLLGVALLAVAVFISVLAFTCFSIYQVCKNQTTIEVHGMRRYRRDLEILNDSYGTNEHLENIFDLGSSMANWQDIMGTSWLEWILPIETFKYKKSKHTKDEKGLYFNVRP------------------------------QVQDRLLSSRCLEDQLLRRVTPRPSLEADRASVEIIDAN-------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .* . . *: : .: . . : . :::: * . . * . . .* *. * : ****.*** * *:*********. :* * * *:*: ** *: :*.. : : . :: : :*: . *::*:* : . *. : ** * :: * . * .*: : . ... . . ", "identical_positions": 46, "similar_positions": 60, "identity": "8.63%" }, { "cls_id": "homologset.agr.SGD:S000005272", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q78YY6-1", "uniprot_id": "DJC15_MOUSE", "id": "Q78YY6-1", "name": "DnaJ homolog subfamily C member 15", "aln": "MATGGGVTSR-EGLRYAEYLPPSAQRSDADIDHT-AGRRLLAVGLGVAAVAFAGRYAFQIWKPLEQVITATARKIS----SPSFSS---------------------YYKGGFEQKMSKREASLILGVSP----SAGKAKIRTAHKRIMILNHPDKGGSPYLASKINEAKD-LLEASSKAN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GJ68-1", "uniprot_id": "A0A8I6GJ68_RAT", "id": "A0A8I6GJ68-1", "name": "", "aln": "MATGGGVTSR-EGLRYAEYLPPSAQRPDADIDHT-AGRRLLAVGLGVAAVAFAGRYAFQIWKPLEQVLTATARKIS----SPSFSS---------------------YYKGGFEQKMSRREASLILGVSP----SAGKAKIRTAHKRIMILNHPDKGGSPYLASKINEAKD-LLEASSKAN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5T4-1", "uniprot_id": "DJC15_HUMAN", "id": "Q9Y5T4-1", "name": "DnaJ homolog subfamily C member 15", "aln": "MAARGVIAPVGESLRYAEYLQPSAKRPDADVDQQRLVRSLIAVGLGVAALAFAGRYAFRIWKPLEQVITETAKKIS----TPSFSS---------------------YYKGGFEQKMSRREAGLILGVSP----SAGKAKIRTAHRRVMILNHPDKGGSPYVAAKINEAKD-LLETTTKH---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96DA6-1", "uniprot_id": "TIM14_HUMAN", "id": "Q96DA6-1", "name": "Mitochondrial import inner membrane translocase subunit TIM14", "aln": "MAS-----------------------------------TVVAVGLTIAAAGFAGRYVLQAMKHMEPQVKQVFQSLP----KSAFSGG--------------------YYRGGFEPKMTKREAALILGVSP----TANKGKIRDAHRRIMLLNHPDKGGSPYIAAKINEAKD-LLEGQAKK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CQV7-1", "uniprot_id": "TIM14_MOUSE", "id": "Q9CQV7-1", "name": "Mitochondrial import inner membrane translocase subunit TIM14", "aln": "MAS-----------------------------------TVVAVGLTIAAAGFAGRYVLQAMKHVEPQVKQVFQSLP----KSAFGGG--------------------YYRGGFEPKMTKREAALILGVSP----TANKGKIRDAHRRIMLLNHPDKGGSPYIAAKINEAKD-LLEGQAKK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PBT7-1", "uniprot_id": "TIM14_DANRE", "id": "Q6PBT7-1", "name": "Mitochondrial import inner membrane translocase subunit TIM14", "aln": "MAS-----------------------------------TMVAVGLTLAAAGFTGRYAVRAMKHMEPQVKQALEAS-----KSAFGSG--------------------YYRGGFDPKMNRREASLILGVSP----TANKTKIREAHRKLMILNHPDRGGSPYLAAKINEAKD-LLDGQAKK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTJ8-1", "uniprot_id": "TIM14_DROME", "id": "Q9VTJ8-1", "name": "Mitochondrial import inner membrane translocase subunit TIM14", "aln": "MAS-----------------------------------SVILAGLSVAAVGFAGKHLMRRMPQMTTKFNEALKNLPKYDAESMAASK--------------------YYKGGFDPKMNKREASLILGVSP----SASKIKIKDAHKKIMLLNHPDRGGSPYLAAKINEAKD-FLDKAK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42834-1", "uniprot_id": "MDJ2_YEAST", "id": "P42834-1", "name": "Mitochondrial DnaJ homolog 2", "aln": "MVLP------------------------------------IIIGLGVTMVALSVKSGLNAWTVYKTLSPLTIAKLNNIRIENPTAGYRDALKFKSSLIDEELKNRLNQYQGGFAPRMTEPEALLILDISAREINHLDEKLLKKKHRKAMVRNHPDRGGSPYMAAKINEAKE-VLERSVLLRKR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8IRP6-1", "uniprot_id": "Q8IRP6_DROME", "id": "Q8IRP6-1", "name": "", "aln": "MQASKVSPS---------------------------FSDYLPLVSTVVAVGVAT-CCVAAQIFRSPNSTKTIGQLRLCFGNLGTGR---------------------FYSGCFQKRMSHREASKILSISP----------NAPWIRRAMLAKHPDRNGSPYLAGKIHKPKNGLLEGRNRFR--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : :. ..: . . . * * * :*.. ** **.:*. :: *: :***:.****:*.**::.*: .*: ", "identical_positions": 23, "similar_positions": 29, "identity": "12.57%" }, { "cls_id": "homologset.agr.SGD:S000005273", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54777-1", "uniprot_id": "PEX6_RAT", "id": "P54777-1", "name": "Peroxisomal ATPase PEX6", "aln": "-----------------MALAVLHVLEPFPTETPPLAVLLPPGGPWPVTGVGLVLALRPASESPAGPALLVAAVEGSGAQCEQRGPGPPPLLVSRTLLRVLALSPGARVRARPVRRPPALGWALLGTSPGPGLGPRVGPLLVRRGETLPVPGSRVLETRPALQGLLGPGTRLAVTELQGRTKLDPESRDHNHPPPPPVVSSFAVSHSIRQLRGVLGGTGDALGVSRSCLRSLGLFQGEWVWVARVGELPNTSQPHLAQVQVLEPRWDLSARLGPNSGQ-PGEPLADGLVFVPATLAFNLGCDPLEVGELRIQRYLEDSTAAEDKGSCSLLPGPPFARELHIEVLPSPHCGVNGKYDHVLYQHFHTPRVVQE--GDVLCVSTAGQVEILEGSLERLPRWREVFFKVKKTVGEAPDGPASAFLADTTHTSLYLAGTTLSR-VPPLPS----GRSPPWDSLSPPGLEALVNELCAVLKPHLQPGGTLLTG---TSCVLLQGPPGSGKTTAVTAACSRLGLHLLKVPCSSLCADSSRTVETKLQTTFSRAR------RCRPVVLLLTALD--LLGRDRDGLGEDARVVATLRHLLLDEDP--LSRCPPLMVVATTSRVQDLPTDVRTAFPHELEVPVLSESQRLSVLQALTA---------------HLPLGQEVNLSQLARRCAGFVVGDLYALLTHASRAACTRIKAAGLA--MSEEDEGELCAAGFPLLAEDFGQALDQLQTAHSQAVGAPKIPSVSWHDVGGLQDVKKEILETIQLPLEHPELLSLGLR-RSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSGGVMDRVVSQLLAELDGLHS---TQDVFVIGATNRPDLLDPALLRPGRFDKLVFVGASEDRASQLRVLSAITRKFKLEASVSLMNVLDCCPPQLTGADLYSLCSDAMMTALKRRVRDLEEG----LEPRSS-----------------ALLLTMEDLLQAAARLQPSVSEQELLRYKRIQRKFAAC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LC9-1", "uniprot_id": "PEX6_MOUSE", "id": "Q99LC9-1", "name": "Peroxisomal ATPase PEX6", "aln": "-----------------MALAVLRVLDPFPTETPPLAVLLPPGGPWPATGLGLVLALRPASESPAKPALLVAAVEGSGAQGEQRGPGPPPLLVSRALLRVLALGPGARVRARLVRRPPALGWALLATAPGPGLGPRVGPLLVRRGETLPVPGSRVLETRPALQGLLGPGTRLAVTELRGRAKLGQESRDHSHPPPPPVVSSFAASHSVRRLRGVLGGTGDALGVSRSCLRSLGLFQGEWVWVAQVAELPNSSQPRLAQVQVLEPRWELSERLGPNSGQQPGEPLADGLVFLPATLAFNLGCDPLEVGELRIQRYLEGSIAPENKGSCSPLPGPPFARELHIEILSSPHYSANGNYDHVLYRHFQTPRVVQE--GDVLCVSTAGQVEILEGSLERLPRWREMFFKVKKTVGEAPEGPASAFLADTTHTSLYLAGTALSH-VPSLPS----GRSPPWDSLSPPGLEALVNELCAILKPHLQPGGTLLTG---TSCVLLQGPPGSGKTTAVTAACSRLGLHLLKVPCSSLCADSSRAVETKLQATFSRAR------RCRPAVLLLTAVD--LLGRDRDGLGEDARVAATLRHLLLDEDA--LSRCPPLMVVATTSRVQDLPTDVQTAFPHELEVPVLSEAQRLSILQALTA---------------HLPLGQEVNLPQLARRCAGFVVGDLYALLTHTCRAACTRIRASGSAGGLSEEDEGDLCVAGFPLLAEDFGQALDQLQTAHSQAVGAPRIPSVSWHDVGGLQDVKKEILETIQLPLEHPELLSLGLR-RSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSGGVMDRVVSQLLAELDGLHS---TQDVFVIGATNRPDLLDPALLRPGRFDKLVFVGASEDRASQLRVLSAITRKFKLEASVSLANVLDCCPPQLTGADLYSLCSDAMMTALKRRVRDLEEG----LELRSS-----------------ALLLTMEDLLQAAARLQPSVSEQELLRYKRIQRKFAAC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13608-1", "uniprot_id": "PEX6_HUMAN", "id": "Q13608-1", "name": "Peroxisomal ATPase PEX6", "aln": "-----------------MALAVLRVLEPFPTETPPLAVLLPPGGPWPAAELGLVLALRPAGESPAGPALLVAALEGPDAGTEEQGPGPPQLLVSRALLRLLALGSGAWVRARAVRRPPALGWALLGTSLGPGLGPRVGPLLVRRGETLPVPGPRVLETRPALQGLLGPGTRLAVTELRGRARLCPESGDSSRPPPPPVVSSFAVSGTVRRLQGVLGGTGDSLGVSRSCLRGLGLFQGEWVWVAQARESSNTSQPHLARVQVLEPRWDLSDRLGPGSGP-LGEPLADGLALVPATLAFNLGCDPLEMGELRIQRYLEGSIAPEDKGSCSLLPGPPFARELHIEIVSSPHYSTNGNYDGVLYRHFQIPRVVQE--GDVLCVPTIGQVEILEGSPEKLPRWREMFFKVKKTVGEAPDGPASAYLADTTHTSLYMVGSTLSP-VPWLPS----EESTLWSSLSPPGLEALVSELCAVLKPRLQPGGALLTG---TSSVLLRGPPGCGKTTVVAAACSHLGLHLLKVPCSSLCAESSGAVETKLQAIFSRAR------RCRPAVLLLTAVD--LLGRDRDGLGEDARVMAVLRHLLLNEDP--LNSCPPLMVVATTSRAQDLPADVQTAFPHELEVPALSEGQRLSILRALTA---------------HLPLGQEVNLAQLARRCAGFVVGDLYALLTHSSRAACTRIKNSGLAGGLTEEDEGELCAAGFPLLAEDFGQALEQLQTAHSQAVGAPKIPSVSWHDVGGLQEVKKEILETIQLPLEHPELLSLGLR-RSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSGGVMDRVVSQLLAELDGLHS---TQDVFVIGATNRPDLLDPALLRPGRFDKLVFVGANEDRASQLRVLSAITRKFKLEPSVSLVNVLDCCPPQLTGADLYSLCSDAMTAALKRRVHDLEEG----LEPGSS-----------------ALMLTMEDLLQAAARLQPSVSEQELLRYKRIQRKFAAC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z8D1-1", "uniprot_id": "A1Z8D1_DROME", "id": "A1Z8D1-1", "name": "Peroxisomal ATPase PEX6", "aln": "------------------------------------------------------------MKRRVIVKKKKVVGKRNSVSFDQQDPGQPRFSFSGRVQELVEG-----YNSAIQLLAPKWPWFLYPGYLTYAVYWRYAKYYKGKFLLTPIPN--------RLYDLLIKNEQIKSEHLVFASQEVYEN--------------YAESPDVNFVNLVIRGRRVRIGKP------------------LASDEGNMTQTVIKQMLQEAPHTIVAQILPAAQCQ-------------PNCLYVQENFYGNILDRFQIR--SNCWVQVEHFADEQTIPG--IATKAHVYLVADPHELPAELTEVILSNYFNTPRLMHR--GHTYRIEVNAELVGTATYAHYYLIFAHLRHVHLKCIHLETKGSEFELQAIVAKNFSNLVQVPASHSFLPRQV----LDSMAIVENYPSGLRKPYKLLRSSVDAFLPKKSACLSSKHIFPVFLLQGERGSGKSKLVSAVAQELGMHIYGADCAEIVSQVPSHTEMKLKAVFAKSQ------VCEPLMICFHNFE--IFGIDNEGN-EDLRLLSAFHVQVQELFN--RDRKHPIVVVALTS-DRHLKPMIQGLFLEIINIDMPSKEERFEILRWMHVRETFNDIIYNQKAIEQLPLFSRENQSQFMPRISPSWRETLNVLQDVAAKSQGFLLGDLQLLYDNAVRMKIRNRLGRTTLDMSHFAKNLTDMQSSFADSLGAPKVPKVYWSDIGGLAKLKDEIQSSIGLPLKHVHLMGKNLR-RSGILLYGPPGTGKTLVAKAVATECNLSFLSVQGPELLNMYVGQSEQNVREVFSRARSAAPCVLFLDELDSLAPNRGVAGDSGGVMDRVVSQLLAEMDGMSDGDTSKPIFILAATNRPDLIDPALLRPGRFDKLFYVGPCSTAEDKAAVLRAQTQRFALDAGVDMEQIAERLKSEMSGADLYSICSNAWLSAVRRTIDGHLSGTISEKELVPE-----------------NVIVQEEDFTKSFNKFVPSISAKDLEYFNNLKASYSV-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33760-1", "uniprot_id": "PEX6_YEAST", "id": "P33760-1", "name": "Peroxisomal ATPase PEX6", "aln": "MKASLTFSLSGIYAPCSISRDIYLEYGDKKAECLYGTIRLPQYGPGCTPGKIVHCVLDDSLPFCSIVVPSKLFGFMPTQPTMDFCYFEPILDNVVPVLDSVTFLINEQLYSKLMDLPQEMQQIQFLHY-KYNINSMETVVHSRDILTSGLCQILNCSPFPQGLVDFTETQLILVNDTEQKLSALKYANEDEEYALPKIGTNSALSIDLESLPCTISRDLLRPAPHINDDNSIYAFTDAETLLRLDVTSGSFITVSNMGCVRLVKLFVLLLPNGFKKRT---------IYAPPKIIASFPDCSVVTISKSNIG---HTDIPIANQVFISRVGGWLQSQKCFQNIILTTLKKFFSESKRILCQNDLIPIAFDSSMADLNIAEENDESDDEDELGQYYKNDSLVWFFVTSAELDCFSKDNSHFIIDPNRTKLITTNITNRRPLPLSRSNLQRYYGFAETFYYDLHIFPYVRQLVNILETSFNCSQRGITLN--ASVLLHSTTNNVGKATMVRFASKYLGIHLLEIDCLSLTSNSRQLDSTSKIIGYIRAKCENVLPYASPAVIFLAHLDSILLDVNANQDPEAIKLQKSINFEMSKLLDDFTFKFPGTTFVGSVNNIDNVPSSFRSHMRFEILVPVPSEAQRLRIFQWYLS-----------SHELNRDVQQKVPVSYMDNISFSSLSSYSAGLTPLDIKSIVETARMTATARFYQESKKCGWLPQSILITQEDLSKATSKARNEFSVSIGAPQIPNVTWDDIGGIDFVKGEILDTIDMPLKHPELFTSGMKKRSGILFYGPPGTGKTLMAKAIATNFSLNFFSVKGPELLNMYIGESEANVRRVFQKAREAKPCVIFFDEIDSVAPKRGNQGDSGGVMDRIVSQLLAELDGMST--DADGVFVIGATNRPDLLDEALLRPGRFDKLLYLGIPDTDTKQLNILEALTRKFVLDNDVKLIELAKLCPFNYTGADFYALCSDAMLNAMSRIARMVEKKVSQHNELTGENISTRRWFDKIATKEDTKVVVKMEDFLKAQEQLTPSVSRAELNHYEAVRANFEGA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : : : : . : : : : . * * :. : .: . . : . * : . :.. .* . . . : * : : . :: . . :* . * .. .. : . : . . . :. . . . . : * :.. : :: . .* . **:. * ... **:*: * .: :: . . : ::: . * :: : .: ::. : : * :: :. : . .*. .. .: . .: : : : *: :*: ::: : : .. . : * :: : : ..:.: . :. .: ::***::*.* * *:**: :* ** .:* :**:* .*: .:: ***:*::*********:***:**: .*.*:**:****:***:*:** ***.** :** * **::*:**:**:**.** *********:*******:**: :. :*::.*******:* ***********.::* . .: :* * *::* *: .*.: :: . : :***:*::**:* *: * . * . ::: **: :: :: **:* :* :: :: .: ", "identical_positions": 152, "similar_positions": 226, "identity": "14.37%" }, { "cls_id": "homologset.agr.SGD:S000005274", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZVU7-1", "uniprot_id": "D3ZVU7_RAT", "id": "D3ZVU7-1", "name": "Histone deacetylase 1", "aln": "---------MAQTQG-TERKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHYAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGDGYTIHNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHTPGVQMQAIPEDAIPEESGDEDEEDPDKPISICSSDKCIACEEEFPDSDEEGEGGRENSSNFKK-AKRVKTEDEK---EKDPEEKKEVTEE-EKTKE---EKPEAKGVKEEVKMA---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4QQW4-1", "uniprot_id": "HDAC1_RAT", "id": "Q4QQW4-1", "name": "Histone deacetylase 1", "aln": "---------MAQTQG-TKRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDG--VEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEEDPDKRISICSSDKRIACEEEFSDSDEEGEGGRKNSSNFKK-AKRVKTEDEK---EKDPEEKKEVTEE-EKTKE---EKPEAKGVKEEVKMA---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O09106-1", "uniprot_id": "HDAC1_MOUSE", "id": "O09106-1", "name": "Histone deacetylase 1", "aln": "---------MAQTQG-TKRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDG--VEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEEDPDKRISICSSDKRIACEEEFSDSDEEGEGGRKNSSNFKK-AKRVKTEDEK---EKDPEEKKEVTEE-EKTKE---EKPEAKGVKEEVKLA---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13547-1", "uniprot_id": "HDAC1_HUMAN", "id": "Q13547-1", "name": "Histone deacetylase 1", "aln": "---------MAQTQG-TRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDG--VEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKK-AKRVKTEDEK---EKDPEEKKEVTEE-EKTKE---EKPEAKGVKEEVKLA---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70288-1", "uniprot_id": "HDAC2_MOUSE", "id": "P70288-1", "name": "Histone deacetylase 2", "aln": "---------MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDG--VEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVAKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDK---KETEDKKTDVKEE-DKSKDNSGEKTDPKGAKSEQLSNP--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92769-1", "uniprot_id": "HDAC2_HUMAN", "id": "Q92769-1", "name": "Histone deacetylase 2", "aln": "---------MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDG--VEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDK---KETEDKKTDVKEE-DKSKDNSGEKTDTKGTKSEQLSNP--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LVE7-1", "uniprot_id": "A0ABK0LVE7_RAT", "id": "A0ABK0LVE7-1", "name": "Histone deacetylase 2", "aln": "---------MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAVLELLKYHQRVLYIDIDIHHGDG--VEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDK---KEAEDKRTDVKEE-DKSKDNSGEKTDTKGAKSEQLNNP--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q94517-1", "uniprot_id": "HDAC1_DROME", "id": "Q94517-1", "name": "Histone deacetylase HDAC1", "aln": "------------MQSHSKKRVCYYYDSDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDEYVRFLRSIRPDNMSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDG--VEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNIPLRDGMDDDAYESIFVPIISKVMETFQPAAVVLQCGADSLTGDRLGCFNLTVKGHGKCVEFVKKYNLPFLMVGGGGYTIRNVSRCWTYETSVALAVEIANELPYNDYFEYFGPDFKLHISPSNMTNQNTSEYLEKIKNRLFENLRMLPHAPGVQIQAIPEDAINDESDDEDKVDKDDRLPQSDKDKRIVPENEYSDSEDEGEGGRRDNRSYKGQRKRPRLDKDTNSNKASSETSSEIKDEKEKGDGADGEESTASNTNSNNNSNNKSDNDAGATANAGSGSGSGSGAGAKGAKENNI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32561-1", "uniprot_id": "RPD3_YEAST", "id": "P32561-1", "name": "Histone deacetylase RPD3", "aln": "MVYEATPFDPITVKPSDKRRVAYFYDADVGNYAYGAGHPMKPHRIRMAHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYIDFLSRVTPDNLEMFKRESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRGKCDVAVNYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRVLYIDIDVHHGDG--VEEAFYTTDRVMTCSFHKYGEFFPGTGELRDIGVGAGKNYAVNVPLRDGIDDATYRSVFEPVIKKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMEGHANCVNYVKSFGIPMMVVGGGGYTMRNVARTWCFETGLLNNVVLDKDLPYNEYYEYYGPDYKLSVRPSNMFNVNTPEYLDKVMTNIFANLENTKYAPSVQLNHTPRDAEDLGDVEED-----------------------SAEAKDTKGGSQY-------ARDLHVEHDN-----------EFY-----------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .::*.*:**.*:*** ** ***********:*.*::*****:******.: *. :** ::*:*:*: ** : ***:. :.:: :****:********:*:*.:* ***: .*.:**: ::.:*:.****:***********:*****.::***:** ********:***** ************* *******:*****:*****.* ** **** *:***:** :* :* *::.*:** :**:*******.***:*********:::**.:**: .*.:.:*::::**.***::**:* * :**.: : ::****:*:**:***:** : **** * ** **::*: .:* **. ::*.**:: *.** . :** . . .: :** . : : :.:. :. ", "identical_positions": 227, "similar_positions": 126, "identity": "42.43%" }, { "cls_id": "homologset.agr.SGD:S000005275", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43488-1", "uniprot_id": "ARK72_HUMAN", "id": "O43488-1", "name": "Aflatoxin B1 aldehyde reductase member 2", "aln": "MLSAASRVVSRAAVHCALRSPPPEARALAMSRPPPPRVAS--------VLGTMEMG-------RRMDAPASAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLK-----------PDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYED-KDGKQPVGRFFG---NSWAETYRNRFWKEHHFEAIALVEKALQAAYGASAPSVTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAATEEGP-----LEPAVVDAFNQAWHLVAHECPNYFR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CG45-1", "uniprot_id": "ARK72_RAT", "id": "Q8CG45-1", "name": "Aflatoxin B1 aldehyde reductase member 2", "aln": "MLRAVSRAVSRAAVRCAWRSGPSVARPLAMSRSPAPRAVSGAPLRPGTVLGTMEMG-------RRMDASASAATVRAFLERGLNELDTAFMYCDGQSESILGSLGLGLGSGDCTVKIATKANPWDGKSLK-----------PDSVRSQLETSLKRLQCPRVDLFYLHAPDHGTPIVETLQACQQLHQEGKFVELGLSNYASWEVAEIYTLCKSNGWILPTVYQGMYNATTRQVETELLPCLRYFGLRFYAYNPLAGGLLTGKYRYED-KDGKQPEGRFFG---NSWSETYRNRFWKEHHFEAIALVEKALKTTYGTSAPSMTSAALRWMYHHSQLQGTRGDAVILGMSSLEQLEQNLAATEEGP-----LEPAVVEAFNQAWNVVAHECPNYFR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95154-1", "uniprot_id": "ARK73_HUMAN", "id": "O95154-1", "name": "Aldo-keto reductase family 7 member A3", "aln": "-----------------------MSRQLSRARPAT-------------VLGAMEMG-------RRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLK-----------PDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYED-KNGKQPVGRFFG---NTWAEMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGP-----LEPAVVDAFNQAWHLVTHECPNYFR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NHP1-1", "uniprot_id": "ARK74_HUMAN", "id": "Q8NHP1-1", "name": "Aflatoxin B1 aldehyde reductase member 4", "aln": "-----------------------MSRQLSRARPAT-------------VLGAMEMG-------RRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVKIATKANPWIGNSLK-----------PDSVRSQLETSLKRLQCPRVDLFYLHAPDHSAPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYSATTRQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYED-KDGKQPVGRFFG---TQWAEIYRNHFWKEHHFEGIALVEKALQAAYGASAPSMTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGP-----LEPAVVDAFNQAWHLFAHECPNYFI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38918-1", "uniprot_id": "ARK73_RAT", "id": "P38918-1", "name": "Aldo-keto reductase family 7 member A3", "aln": "---------------------------MSQARPAT-------------VLGAMEMG-------RRMDVTSSSASVRAFLQRGHTEIDTAFVYANGQSETILGDLGLGLGRSGCKVKIATKAAPMFGKTLK-----------PADVRFQLETSLKRLQCPRVDLFYLHFPDHGTPIEETLQACHQLHQEGKFVELGLSNYVSWEVAEICTLCKKNGWIMPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGRYKYQD-KDGKNPESRFFG---NPFSQLYMDRYWKEEHFNGIALVEKALKTTYGPTAPSMISAAVRWMYHHSQLKGTQGDAVILGMSSLEQLEQNLALVEEGP-----LEPAVVDAFDQAWNLVAHECPNYFR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42884-1", "uniprot_id": "AAD14_YEAST", "id": "P42884-1", "name": "Putative aryl-alcohol dehydrogenase AAD14", "aln": "---------MTDLFKPLPEPPTELGRLRVLSKTAGIRVSP-------LILGGASIGDAWSGFMGSMNKEQAFELLDAFYEAGGNCIDTANSYQNEESEIWIGEWMASRKLRDQIVIATKFTGDYKKYEVGGGKSANYCGNHKRSLHVSVRDSLRKLQTDWIDILYIHWWDYMSSIEEVMDSLHILVQQGKVLYLGVSDTPAWVVSAANYYATSHGKTPFSVYQGKWNVLNRDFERDIIPMARHFGMALAPWDVMGGGRFQSKKAMEERKKNGEGLRTFVGGPEQTELEVKISEALTKIAEEHGTESVTAIAIAYVRSKAKNVFPLIGGRKIEHLKQNIEALSIKLTPEQIEYLESIVPFDVGFPKSLIGDDPAVTKKLSPLTSMSARIAFDN--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.. :** .:* *: : ** : * . :*** * : :** :* . * . : : .:: .:. **::** :*::*:* *: :.: *.: : : * *:**.: **:*: :* *: ...:* :**** :.. .*:.* :::* *:**: : .:: :.** : .: :: *.. : *.* : .. .: : : .*: :* : .. . : . :. .. :: * ..:* **. :. * :***.. :. : :: . : ", "identical_positions": 59, "similar_positions": 115, "identity": "14.97%" }, { "cls_id": "homologset.agr.SGD:S000005284", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VHF5-1", "uniprot_id": "CISY_RAT", "id": "Q8VHF5-1", "name": "Citrate synthase, mitochondrial", "aln": "---------MALLTA---AARLLGAKNSSCLVLAARH-ASASSTNLKDILSNLIPKEQARVKTFRQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGYSIPECQKLLPKAKGGEEPLPEGLFWLLVTGQMPTEEQVSWLSQEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGINRTKYWELIYEDCMDLIAKLPCVAAKIYRNLYREGSSIGAIDSKLDWSHNFTNMLCYTEPQFTELMRLYLTIHSDHDGGNVSAHTSHLVGSALSDTYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYSCQREFALKHLPKDPMFKLVAQLYKIVPNILLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLMKFVDSKSG--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CZU6-1", "uniprot_id": "CISY_MOUSE", "id": "Q9CZU6-1", "name": "Citrate synthase, mitochondrial", "aln": "---------MALLTA---ATRLLGAKNSSCLVLAARH-ASASSTNLKDVLSNLIPKEQARIKTFKQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGYSIPECQKMLPKAKGGEEPLPEGLFWLLVTGQMPTEEQVSWLSREWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGMNRAKYWELIYEDCMDLIAKLPCVAAKIYRNLYREGSSIGAIDSRLDWSHNFTNMLGYTDPQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYSCQREFALKHLPKDPMFKLVAQLYKIVPNILLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLMKFVDSK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75390-1", "uniprot_id": "CISY_HUMAN", "id": "O75390-1", "name": "Citrate synthase, mitochondrial", "aln": "---------MALLTA---AARLLGTKNASCLVLAARH-ASASSTNLKDILADLIPKEQARIKTFRQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKAKGGEEPLPEGLFWLLVTGHIPTEEQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSESNFARAYAQGISRTKYWELIYEDSMDLIAKLPCVAAKIYRNLYREGSGIGAIDSNLDWSHNFTNMLGYTDHQFTELTRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTEGLMKFVDSKSG--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVY5-1", "uniprot_id": "CISY_DANRE", "id": "Q7ZVY5-1", "name": "Citrate synthase, mitochondrial", "aln": "---------MSFLSISRLAPRLLSSKNAACVVVAARN-ASAS-TNLKDVLSDLVPKEQSRIKNFKQQYGKTSIGQITVDMVYGGMRGVKGLVYETSVLDPDEGIRFRGYSIPECQQLLPKAPGGEEPLPEGLFWLLVTGQVPTEEQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQFSAAITALNSESSFARAYSEGVNKAKYWEFVYEDSMDLIAKLPCVAAKIYRNLYREGSSIGAIDSNLDWSHNFTNMLGYTEPQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFSAAMNGLAGPLHGLANQEVLVWLTALQKELGGEVSDEKMRDYIWNTLKSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLVWSRALGFPLERPKSMSTDGLMALVGAKSG--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W401-1", "uniprot_id": "CISY_DROME", "id": "Q9W401-1", "name": "Probable citrate synthase, mitochondrial", "aln": "---------MSLYRIS--ARKLSEAQKLPNVGAYVRM-IAADGKSLRDVLAAKVPQEQERVKNFRKQHGATKMGETTIDMMYGGMRGIKALVTETSVLDADEGIRFRGLSIPECQKVLPAADGGTEPLPEGLFWLLLTGEVPTKSQVQQLSREWAERAALPQHVVTMLNNMPTTLHPMSQFAAAVTALNHDSKFAKAYSDGVHKSKYWEYVYEDSMDLIAKLPVVAATIYCNTYRGGKGSRSIDSSLDWSANFVKMLGYDNAPFTELMRLYLTIHSDHEGGNVSAHTVHLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLVWLRKLQKEAGNNPSEEQLKEYIWKTLKSGQVVPGYGHAVLRKTDPRYTCQREFALKHLPEDETFQLVSKIYKVVPPILTETGKVKNPWPNVDAHSGVLLQYYGMKEMNYYTVLFGVSRALGVLASLVWDRALGLPIERPKSFSTDLLVKMVQK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00890-1", "uniprot_id": "CISY1_YEAST", "id": "P00890-1", "name": "Citrate synthase, mitochondrial", "aln": "MSAILSTTSKSFLSRGS-TRQCQNMQKALFALLNARHYSSASEQTLKERFAEIIPAKAEEIKKFKKEHGKTVIGEVLLEQAYGGMRGIKGLVWEGSVLDPEEGIRFRGRTIPEIQRELPKAEGSTEPLPEALFWLLLTGEIPTDAQVKALSADLAARSEIPEHVIQLLDSLPKDLHPMAQFSIAVTALESESKFAKAYAQGVSKKEYWSYTFEDSLDLLGKLPVIASKIYRNVFKDGK-ITSTDPNADYGKNLAQLLGYENKDFIDLMRLYLTIHSDHEGGNVSAHTTHLVGSALSSPYLSLAAGLNGLAGPLHGRANQEVLEWLFKLREEVKGDYSKETIEKYLWDTLNAGRVVPGYGHAVLRKTDPRYTAQREFALKHFPDYELFKLVSTIYEVAPGVLTKHGKTKNPWPNVDSHSGVLLQYYGLTEASFYTVLFGVARAIGVLPQLIIDRAVGAPIERPKSFSTEKYKELVKKIESKN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : : :: .* :*. .*:: :: :* : .:*.*::::* * :*: :: ******:*.** * ****.:******* :*** *: ** * *. *****.*****:**.:**. **. ** : * *: :*.**: :*:.:*. ****:*:: *:***: :*.**:**::*: : :**. :**.:**:.*** :*:.** * :: *. : *. *:. *:.::* * : * :* **********:******** ********..***::*.:********* ****** ** *::* : *.* :..*:*.**::*:*****************:.********:*. *:**: :*::.* :* : **.********:**********:.* .:*******:**:***..*: .**:* *:*****:**: :* ", "identical_positions": 233, "similar_positions": 133, "identity": "48.44%" }, { "cls_id": "homologset.agr.SGD:S000005286", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQ56-1", "uniprot_id": "D3ZQ56_RAT", "id": "D3ZQ56-1", "name": "DNA-directed RNA polymerase III subunit RPC6", "aln": "MGAPSRPHEEGPARPKEEGPSSLPRPHPWRAPPPVPENSSALLRATFPLVLKTTLMAEVKVKVQPPDADPVEIENRIIELCHQFPHGITDQVIQNEMPHIEAQQRAVAINRLLSMGQLDLLRSNTGLLYRIKDSQN-AGKMKGSDNQEKLVYQIIEDAGNKGIWSRDIRYKSNLPLTEINKILKNLESKKLIKAVKSVAASKKKVYMLYNLQPDRSVTGGAWYSDQDFESEFVEVLNQQCFKFLQSK--AETARESKQNP-----VIQRNSSFASSHEVWKYICELGISKVELSMEDIETILNTLIYDGKVDMTIIAAKEGTVGSVDGHMKLYRAVNPILPPTGLVRAPCGLCPVFDDCHEGGEISPSNCIYMTEWLEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H1D9-1", "uniprot_id": "RPC6_HUMAN", "id": "Q9H1D9-1", "name": "DNA-directed RNA polymerase III subunit RPC6", "aln": "-------------------------------------------------------MAEVKVKVQPPDADPVEIENRIIELCHQFPHGITDQVIQNEMPHIEAQQRAVAINRLLSMGQLDLLRSNTGLLYRIKDSQN-AGKMKGSDNQEKLVYQIIEDAGNKGIWSRDIRYKSNLPLTEINKILKNLESKKLIKAVKSVAASKKKVYMLYNLQPDRSVTGGAWYSDQDFESEFVEVLNQQCFKFLQSK--AETARESKQNP-----MIQRNSSFASSHEVWKYICELGISKVELSMEDIETILNTLIYDGKVEMTIIAAKEGTVGSVDGHMKLYRAVNPIIPPTGLVRAPCGLCPVFDDCHEGGEISPSNCIYMTEWLEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q921X6-1", "uniprot_id": "RPC6_MOUSE", "id": "Q921X6-1", "name": "DNA-directed RNA polymerase III subunit RPC6", "aln": "-------------------------------------------------------MAEVKVKVQPPDADPVEIENRIIELCHQFPHGITDQVIQNEMPHIEAQQRAVAINRLLSMGQLDLLRSNTGLLYRIKDSQN-AGKMKGSDNQEKLVYQIIEDAGNKGIWSRDIRYKSNLPLTEINKILKNLESKKLIKAVKSVAASKKKVYMLYNLQPDRSVTGGAWYSDQDFESEFVEVLNQQCFKFLQSK--AETARESKQNP-----VIQRNSSFASSHEVWKYICELGISKVELSMEDIETILNTLIYDGKVEMTIIAAKEGTVGSVDGHMKLYRAVNPILPPTGVVRAPCGLCPVFEDCHEGGEISPSNCIYMTEWLEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VD25-1", "uniprot_id": "RPC6_DROME", "id": "Q9VD25-1", "name": "DNA-directed RNA polymerase III subunit RPC6", "aln": "--------------------------------------------------------------------MATEVSQLLLAVVQGIPAGATNDDLTKALPDVPAATRVEALNILLQEGGIEILKKGEKLVYRAKDPEKKSALPKDADNEEKVVYGIVEEGGNKGIWIRDIRMKSNLNMIQLNKILKNLETKKLIKAVKSVNASKKKVYMLYNLEPDLSITGGAWYQDQDFEVEFVDVLNQQCLRFLQMK--RDSAEKKREGP-----LAFKQMSCCTVNEVQKFISDLGISKVNLAEADLETILKTVVYDGNAER--VRQQDGSF--------VYRAVNAPLPPTGLVQMPCGICPVIKNCSNCGDVTAITCEYMRDWLD-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32910-1", "uniprot_id": "RPC6_YEAST", "id": "P32910-1", "name": "DNA-directed RNA polymerase III subunit RPC6", "aln": "-------------------------------------------------------MSGMIENGLQLSDNAKTLHSQMMS--KGIGALFTQQELQKQMGIGSLTDLMSIVQELLDKNLIKLVKQNDELKFQG-VLESEAQKKATMSAEEALVYSYIEASGREGIWSKTIKARTNLHQHVVLKCLKSLESQRYVKSVKSVKFPTRKIYMLYSLQPSVDITGGPWFTDGELDIEFINSLLTIVWRFISENTFPNGFKNFENGPKKNVFYAPNVKNYSTTQEILEFITAAQVANVELTPSNIRSLCEVLVYDDKLEKVTHDCYRVTLES---ILQMNQGEGEPEAGNKALEDEEEFSIFNYFKMFPASKHDKEVVYFDEWTI-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . :: : : *:: : : : :: **. . :.:::.. * :: :. : . :* :** :* .*.:*** : *: ::** : * **.**::: :*:**** ..:*:****.*:*. .:***.*: * ::: **:: * :*:. : : .: .:.* . . .: :*: ::* :::*:*: ::.:: :.::**.: : :. : :. . . . :. :. . .. *: :* ", "identical_positions": 50, "similar_positions": 114, "identity": "13.19%" }, { "cls_id": "homologset.agr.SGD:S000005289", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99LI8-1", "uniprot_id": "HGS_MOUSE", "id": "Q99LI8-1", "name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "aln": "-MGRGSGTFERLLDKATSQLLLET--DWESILQICDLIRQGDTQAKYAVNSIKKKVN--DKNPHVALYALEVMESVVKNCGQTVHDEVANKQTMEELKELLKRQ-VEVNVRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFPEFKESD----AMFAAERAPDWVDAEECHRCRVQFGVVTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLN---------KKAEGKASST-----TELPPEYLTSPLSQQSQ------LPPKRDETALQEEEELQLALALSQSEAEEKERMRQKTTYTAHPKAEPTPLASSAPPAGSLYSSPVNSSAPLAEDIDPELARYLNRNYWE-KKQEEARKSPTPSAPVPLTEPAAQPGEGHTAPNSMAEAPLPETDSQPITPCSGPFSE--YQNGESEESHEQFLKALQNAVSTFVNRMKSNHMRGRSITNDSAVLSLFQSINTMHPQLLELLNQLDERRLYYEGLQDKLAQIRDARGALSALREEHREKLRRAAEEAERQRQIQLAQKLEIMRQKKQEYLEVQRQLAIQRLQEQEKERQMRLEQQKQTVQMRAQMPAFP-----------LPYAQLQAMP--TAGGVL-YQPSGPTSFPATFSPAGSVEGSPMHGVYMSQP---APATGPYPSMPGTTADPSMVSAY-MYPTGAPGAQAAPQAQAGPTTSPAYSSYQPTPTPGYQSVASQAPQSLPAIS--QPPQTSNIGYMGSQPMSMGYQPYNMQNLMTALPGQDASLPAQQPYIPGQQPLYQQMAPSTGPPQQQPPVAQPAPTQGPPAQGSEAQLISFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JJ50-1", "uniprot_id": "HGS_RAT", "id": "Q9JJ50-1", "name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "aln": "-MGRGSGTFERLLDKATSQLLLET--DWESILQICDLIRQGDTQAKYAVNSIKKKVN--DKNPHVALYALEVMESVVKNCGQTVHDEVANKQTMEELKELLKRQ-VEVNVRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFPEFKESD----AMFAAERAPDWVDAEECHRCRVQFGVVTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLN---------KKAEGKAAST-----TELPPEYLTSPLSQQSQ------LPPKRDETALQEEEELQLALALSQSEAEEKERMRQKSTYTAHPKSEPAPLASSAPPAGSLYSSPVNSSAPLAEDIDPELARYLNRNYWE-KKQEEARKSPTPSAPVPLTEPAAQPGEGHTAPNSMVEAPLPETDSQPITSCSGPFSEQ-YQNGESEESHEQFLKALQNAVSTFVNRMKSNHMRGRSITNDSAVLSLFQSINSTHPQLLELLNRLDERRLYYEGLQDKLAQIRDARGALSALREEHREKLRRAAEEAERQRQIQLAQKLEIMRQKKQEYLEVQRQLAIQRLQEQEKERQMRLEQQKQTVQMRAQMPAFP-----------LPYAQLQAMP--TAGGVL-YQPSGPTSFPGTFSPAGSVEGSPMHGVYMSQP---APATGPYPSMPGTTADPSMVSAY-MYPAGAPGAQAAPQAQAGPTTNPAYSSYQPTPTPGYQNVASQAPQSLPAIS--QPPQTSNIGYMGSQPMSMGYQPYNMQNLMTTLPGQDASLPAQQPYITGQQPMYQQMAPSTGPPQQQPPVAQPPPTQGPPAQGNETQLISFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14964-1", "uniprot_id": "HGS_HUMAN", "id": "O14964-1", "name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "aln": "-MGRGSGTFERLLDKATSQLLLET--DWESILQICDLIRQGDTQAKYAVNSIKKKVN--DKNPHVALYALEVMESVVKNCGQTVHDEVANKQTMEELKDLLKRQ-VEVNVRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFPEFKESD----AMFAAERAPDWVDAEECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLN---------RKAEGKATST-----TELPPEYLTSPLSQQSQ------LPPKRDETALQEEEELQLALALSQSEAEEKERLRQKSTYTSYPKAEPMPSASSAPPASSLYSSPVNSSAPLAEDIDPELARYLNRNYWE-KKQEEARKSPTPSAPVPLTEPAAQPGEGHAAPTNVVENPLPETDSQPIPPSGGPFSEPQFHNGESEESHEQFLKALQNAVTTFVNRMKSNHMRGRSITNDSAVLSLFQSINGMHPQLLELLNQLDERRLYYEGLQDKLAQIRDARGALSALREEHREKLRRAAEEAERQRQIQLAQKLEIMRQKKQEYLEVQRQLAIQRLQEQEKERQMRLEQQKQTVQMRAQMPAFP-----------LPYAQLQAMP--AAGGVL-YQPSGPASFPSTFSPAGSVEGSPMHGVYMSQP---APAAGPYPSMPSTAADPSMVSAY-MYPAGATGAQAAPQAQAGPTASPAYSSYQPTPTAGYQNVASQAPQSLPAIS--QPPQSSTMGYMGSQSVSMGYQPYNMQNLMTTLPSQDASLPPQQPYIAGQQPMYQQMAPSGGPPQQQPPVAQQPQAQGPPAQGSEAQLISFD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BBJ6-1", "uniprot_id": "A0A8M2BBJ6_DANRE", "id": "A0A8M2BBJ6-1", "name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "aln": "-MGKGGGTFERLLEKATSQLLLET--DWESILQICDLIRQGDTQAKYAIGAIKKKLN--DKNPHVALYALEVLESVVKNCGQTIHDEVASKQTMEELKELFKKQ-PEPNVKNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFPEFKESD----AMFAAERAPDWVDAEECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCFEILNNHPSLSPPPRKAEGKAPSTG---PSELPPEYLTSPLSQQSQVVPTESMPPKRDEAALQEEEELQLAIALSQSEAEEKERMRQKNPYSAYPKADPTPVTSSAPPVSTLYSSPVNSSAPSAEEVDPELARYLNRTYWE-KKQEEVRKSPTPSAPAPVSLAEPVP------VSQPVESHVP---VQPIN-----IVEQQYQNGESEENHEQFLKALQNSVTTFLNRMKSNHMRGRSITNDSAVLSLFQSINNMHPQLLEILNQLDEKRLYYEGLQDKLAQVRDARAALNALREEHREKLRRAAEEAERQRQIQLAQKLEIMRQKKQEYLEMQRQLAIQRLQEQEKERQMRLEQQKHTIQMRAQMPAFS-----------LPYAQMQSLPPNVAGGVV-YPPAGPPSYPGTFSPSGSVEGSPMHGVYMNQAGQ-TAAGGPYQAMP---PDPNMVNAY-MYQTAGNSGQPAAPGQAPPTTTPAYTNYQPTPTQGYQNVVSQA-QSLPPMS--QAAPTNGIAYMG-------YQQYNMQNMMSALPGQDPNMPPQQPYMPGQQPMYQQMAPPGGPQQQSQQQQQPPPPPQAPPGSAEAQLISFD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q960X8-1", "uniprot_id": "HRS_DROME", "id": "Q960X8-1", "name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "aln": "-MFRSS--FDKNLENATSHLRLEP--DWPSILLICDEINQKDVTPKNAFAAIKKKMN--SPNPHSSCYSLLVLESIVKNCGAPVHEEVFTKENCEMFSSFLEST-PHENVRQKMLELVQTWAYAFRSSDKYQAIKDTMTILKAKGHTFPELREAD----AMFTADTAPNWADGRVCHRCRVEFTFTNRKHHCRNCGQVFCGQCTAKQCPLPKYGIEKEVRVCDGCFAALQR-------PTSGSGGAKSGPRPADSELPAEYLNSTLAQQVQ------TPARKTEQELKEEEELQLALALSQSEAEQQKPKLQSLPPAAYRMQQRSPSPEAPPEPKEYHQQPE-------EATNPELAKYLNRSYWEQRKISESSSMASPSAPSPMP-PTPQP--------------------QQIMP--------LQVKSADEVQIDEFAANMRTQVEIFVNRMKSNSSRGRSISNDSSVQTLFMTLTSLHSQQLSYIKEMDDKRMWYEQLQDKLTQIKDSRAALDQLRQEHVEKLRRIAEEQERQRQMQMAQKLDIMRKKKQEYLQYQRQLALQRIQEQEREMQLRQEQQKAQYLMGQSAPPFPYMPPSAVPQHGSPSHQLNNVYNPYAAGVPGYLPQGPAPAPNGHGQFQAIPPG-MYNPAIQQPMPPNLQPGGLMQQPAPPGNPQMMPPMPENQFANNPAAILQLPQQHSIAQPPQIPFQPQP----QQIPGQQPQQIPGQQPQQIPGQQPQQIPGQQPQQIPVQQPQPQPQMGHVMLQQHQAPPAAQAPPVTEIANNQVQAVAAAP--APPQNEPGPAPVKAEEPATAELISFD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40343-1", "uniprot_id": "VPS27_YEAST", "id": "P40343-1", "name": "Vacuolar protein sorting-associated protein 27", "aln": "MSVSTPSELDALIEQATSESIPNGDLDLPIALEISDVLRSRRVNPKDSMRCIKKRILNTADNPNTQLSSWKLTNICVKNGGTPFIKEICSREFMDTMEHVILREDSNEELSELVKTILYELYVAFKNDSQLNYVAKVYDKLISRGIKFPEKLTLSNSPTAMFDSKTPADWIDSDACMICSKKFSLLNRKHHCRSCGGVFCQEHSSNSIPLPDLGIYEPVRVCDSCFEDYD------------------------LKRHDDSKKSKKHRHKR------KKDRDYSTPEDEEELIRKAIELSLKESRNSASSEPIVPVVESKNEVKRQEIE--------------------EEEDPDLKAAIQESLREAEEAKLRSERQKASRQMQPQQPSPQP------------------------------------QPIHSVDLSDEEKDSIYMFASLVEKMKSRPLN--EILEDSKLQNLAQRVFASKARLNYALNDKAQK---YNTLIEMNGKISEIMNIYDRLLEQQLQSIN---LSQQYTLPQVPSDPYNYLTENVQNPAESYQTPPLQQLSSHQYKPQQDVSRQQSVKANSSPTTNID------------------------------HLKTIDVTPHAQQKPQSHVELAPSDPPYPKEE-------------------------------AEDEGTQAVQDEESSTQESRERPY-PVETENGETSINKRPQGITRYD------------------------------FPTVPARKFVQPESTVPLPASS-------------------SEIPIKEERPPSPQEELLIEL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :::***. : * * *.* :.. . .* :. .***:: **: : : : *** * .. .*: .:: : :. .: . :: : : :: **:.. : : : .. : .* *** . *** :. ..:* *. * * :* . .****** ** :** : ::: .:*. ** : ****: *: : : : .* :: : : . .*** :: *: ** .*:.:. . . * :*:* ::.. * .: . . ..* . . * : . . .: . ::::***. . .* :** : .* : :.: :: :: *: * : :: : . * ::: :.:. . : :: : : :: *: : : .:*::..:: : * .:*: . : : . : . .: . . : . . : * : .: * :. . : : :. * . . : . **.: ", "identical_positions": 83, "similar_positions": 196, "identity": "10.02%" }, { "cls_id": "homologset.agr.SGD:S000005290", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AZ50-1", "uniprot_id": "ATG3_RAT", "id": "Q6AZ50-1", "name": "Ubiquitin-like-conjugating enzyme ATG3", "aln": "MQNVINTVKGKALEVAEYLTPVLKESKFKETGVITPEEFVAAGDHLVHHCPTWQWAT-GEELKVKAYLPTGKQFLVTKNVPCYKRCKQMEYSDELEAIIEEDDGDGGWVDTYHN--TGITGITEAVKEITLES-KDSIKLQDCSVLCD----EEEEEEEGEAADMEEYEESGLLETDEATLDTRR----------IVEACKAKADAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDISQDHVKKTVTIENHPHLP-PPPMCSVHPCRHAEVMKKIIETVAEG---------------------------GGELGVHMYLLIFLKFVQAVIPTIEYDYTRHFTM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CPX6-1", "uniprot_id": "ATG3_MOUSE", "id": "Q9CPX6-1", "name": "Ubiquitin-like-conjugating enzyme ATG3", "aln": "MQNVINTVKGKALEVAEYLTPVLKESKFKETGVITPEEFVAAGDHLVHHCPTWQWAT-GEELKVKAYLPTDKQFLVTKNVPCYKRCKQMEYSDELEAIIEEDDGDGGWVDTYHN--TGITGITEAVKEITLES-KDSIKLQDCSALCD----EEDEEDEGEAADMEEYEESGLLETDEATLDTRK----------IVEACKAKADAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDISQDHVKKTVTIENHPHLP-PPPMCSVHPCRHAEVMKKIIETVAEG---------------------------GGELGVHMYLLIFLKFVQAVIPTIEYDYTRHFTM-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NT62-1", "uniprot_id": "ATG3_HUMAN", "id": "Q9NT62-1", "name": "Ubiquitin-like-conjugating enzyme ATG3", "aln": "MQNVINTVKGKALEVAEYLTPVLKESKFKETGVITPEEFVAAGDHLVHHCPTWQWAT-GEELKVKAYLPTGKQFLVTKNVPCYKRCKQMEYSDELEAIIEEDDGDGGWVDTYHN--TGITGITEAVKEITLEN-KDNIRLQDCSALCE----EEEDEDEGEAADMEEYEESGLLETDEATLDTRK----------IVEACKAKTDAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDISQDHVKKTVTIENHPHLP-PPPMCSVHPCRHAEVMKKIIETVAEG---------------------------GGELGVHMYLLIFLKFVQAVIPTIEYDYTRHFTM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PFS7-1", "uniprot_id": "ATG3_DANRE", "id": "Q6PFS7-1", "name": "Ubiquitin-like-conjugating enzyme ATG3", "aln": "MQNVINSVKGTALGVAEFLTPVLKESKFKETGVITPEEFVAAGDHLVHHCPTWKWAS-GEEAKVKPYLPNDKQFLLTRNVPCYKRCKQMEYSDELEAIIEEDDGDGGWVDTFHN--SGVTGVTEAVREISLDN-KDNMNMNVKTGACGNSG-DDDDDEEGEAADMEEYEESGLLETDDATLDTSK----------MADLSKTKAEAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEDRQPLTVDQMYEDISQDHVKKTVTIENHPNLP-PPAMCSVHPCRHAEVMKKIIETVAEG---------------------------GGELGVHMYLLIFLKFVQAVIPTIEYDYTRHFTM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVS6-1", "uniprot_id": "Q9VVS6_DROME", "id": "Q9VVS6-1", "name": "Ubiquitin-like-conjugating enzyme ATG3", "aln": "MQSVLNTVKGTALNVAEYLTPVLKESKFRETGVLTPEEFVAAGDHLVHHCPTWQWAA-GDETKTKPYLPKDKQFLITRNVPCYRRCKQMEYVGE-ETLVEEESGDGGWVETHQLNDDGTTQLEDKICELTMEETKEEMHTPDSDKSAPGAGGQAEDEDDDEAIDMDDFEESGMLELVDPAVATTTRKPEPEAKASPVAAASGDAEASG-DSVLHTRTYDLHISYDKYYQTPRLWVVGYDEQRKPLTVEQMYEDVSQDHAKKTVTMESHPHLP-GPNMASVHPCRHADIMKKIIQTVEEG---------------------------GGQLGVHLYLIIFLKFVQTVIPTIEYDFTQNFNMS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40344-1", "uniprot_id": "ATG3_YEAST", "id": "P40344-1", "name": "Autophagy-related protein 3", "aln": "------MIRSTLSSWREYLTPITHKSTFLTTGQITPEEFVQAGDYLCHMFPTWKWNEESSDISYRDFLPKNKQFLIIRKVPCDKRAEQCVEVEGPDVIMKGFAEDGDEDDVLEYIGSETEHVQSTPAGGTKDSSIDDIDELIQDMEIK---------EEDENDDTEEFN----------------------------------AKGGLAKDMAQERYYDLYIAYSTSYRVPKMYIVGFNSNGSPLSPEQMFEDISADYRTKTATIEKLPFYKNSVLSVSIHPCKHANVMKILLDKVRVVRQRRRKELQEEQELDGVGDWEDLQDDIDDSLRVDQYLIVFLKFITSVTPSIQHDYTMEGW--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.. *:***: ::*.* ** :****** ***:* * ***:* ..: . : :**..****: ::*** :*.:* :.::: **. :. . : . : :. :.: ::.* * :::: :... . : : * ***:*:*.. *:.*::::.*::.: .**: ::*:**:* *: .**.*:*. * *:***:**::** :::.* ...* *. **::****: :* *:*::*:* . ", "identical_positions": 81, "similar_positions": 104, "identity": "22.44%" }, { "cls_id": "homologset.agr.SGD:S000005291", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18424-1", "uniprot_id": "LCAT_RAT", "id": "P18424-1", "name": "Phosphatidylcholine-sterol acyltransferase", "aln": "---------------------------------------------------------------------MGLPGSPWQWVLLLLGLLLPPATSFWLLNVLFPPHTTPKAELSNHTRPVILVPGCM-----------------GNRLEAKLDKPNVVNWLCYRKTEDFFTIWLDFNMFLPLGVDCWIDNTRVVYNRSSGHMSNA----------------------------PGVQIRVPGFGKTYSVEYLDDNK--LAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLA---PRQQDEYYQKLAGLVEEMYAAYG-KPVFLIGHSLGCLHVLHFLLRQPQS----------WKDHFIDGFISLGAPWGGSIKPMRILASGDNQGIPIMSNIKLR-------EEQRITTTSPW-----MFPA--HHVWPEDHVFISTPNFN----------YTGQDFERFFADLHFEEG----------WHMFLQSRDLLAGLP--------------------------APGVEVYCLYGVGMPTAHTYIYDHN---------FPYKDPVAALYEDGDDTVATRSTELCGQWQG---------------RQSQAVHLLPMNG----TDHLNMVFSNKTLEHINAILLGAYRHGTPKSPTASLGPPTKE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16301-1", "uniprot_id": "LCAT_MOUSE", "id": "P16301-1", "name": "Phosphatidylcholine-sterol acyltransferase", "aln": "---------------------------------------------------------------------MGLPGSPWQRVLLLLGLLLPPATPFWLLNVLFPPHTTPKAELSNHTRPVILVPGCL-----------------GNRLEAKLDKPDVVNWMCYRKTEDFFTIWLDFNLFLPLGVDCWIDNTRIVYNHSSGRVSNA----------------------------PGVQIRVPGFGKTESVEYVDDNK--LAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLA---PHQQDEYYKKLAGLVEEMYAAYG-KPVFLIGHSLGCLHVLHFLLRQPQS----------WKDHFIDGFISLGAPWGGSIKAMRILASGDNQGIPILSNIKLK-------EEQRITTTSPW-----MLPA--PHVWPEDHVFISTPNFN----------YTVQDFERFFTDLHFEEG----------WHMFLQSRDLLERLP--------------------------APGVEVYCLYGVGRPTPHTYIYDHN---------FPYKDPVAALYEDGDDTVATRSTELCGQWQG---------------RQSQPVHLLPMNE----TDHLNMVFSNKTLEHINAILLGAYR--TPKSPAASPSPPPPE----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04180-1", "uniprot_id": "LCAT_HUMAN", "id": "P04180-1", "name": "Phosphatidylcholine-sterol acyltransferase", "aln": "---------------------------------------------------------------------MGPPGSPWQWVTLLLGLLLPPAAPFWLLNVLFPPHTTPKAELSNHTRPVILVPGCL-----------------GNQLEAKLDKPDVVNWMCYRKTEDFFTIWLDLNMFLPLGVDCWIDNTRVVYNRSSGLVSNA----------------------------PGVQIRVPGFGKTYSVEYLDSSK--LAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLE---PGQQEEYYRKLAGLVEEMHAAYG-KPVFLIGHSLGCLHLLYFLLRQPQA----------WKDRFIDGFISLGAPWGGSIKPMLVLASGDNQGIPIMSSIKLK-------EEQRITTTSPW-----MFPS--RMAWPEDHVFISTPSFN----------YTGRDFQRFFADLHFEEG----------WYMWLQSRDLLAGLP--------------------------APGVEVYCLYGVGLPTPRTYIYDHG---------FPYTDPVGVLYEDGDDTVATRSTELCGLWQG---------------RQPQPVHLLPLHG----IQHLNMVFSNLTLEHINAILLGAYRQGPPASPTASPEPPPPE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P7R5-1", "uniprot_id": "A0A8M1P7R5_DANRE", "id": "A0A8M1P7R5-1", "name": "Phosphatidylcholine-sterol acyltransferase", "aln": "---------------------------------------------------------------------MG-NSSLFRCVALFL-ILLHQTSGFWLFNVIFPPTAKPR-VINNSTPPLIIVPGNL-----------------GNRLEAKIDKPTLVHWMCYKKSEDWFPLWIDLNMFMPIGVDCWIDNIRIVYNRTTRKTSNA----------------------------PGVDVRVPGFGQTHPIEFLDLNK--LTGYFHTMVQHLVSIGYVRNETVRGAPYDWRIA---PNEQEEYFSRLKNLVEEMHDEYK-QPVYLLGHSMGSNYILYFLNQQTQD----------WKDHYIKGFISLGAPWGGAVKPLRVLASGENDGIPFVSNIKIR-------EEQRMTTTNPW-----MIPS--EETWPKDHTFISTPFFN----------YTNQDYMQFFKDINFEDG----------WYMWDDTRNLTAGLP--------------------------APGVEVYCLYGVGLPTPVTYIYDEQ---------FPNADPIDILYDDGDDTVDSRSMSLCKRWIG---------------KQEQAVHVTEFRG----MPHLDMVFNHKSLTTVQRILEGTYREEKDVGFEQPSSIGFV-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q675A5-1", "uniprot_id": "PAG15_RAT", "id": "Q675A5-1", "name": "Lysosomal phospholipase A and acyltransferase", "aln": "---------------------------------------------------------------------MDRHLCICREIQLRSGLLFPFLLLMMLADLALP---AQR------HPPVVLVPGDL-----------------GNQLEAKLDKPKVVHYLCSKRTDSYFTLWLNLELLLPVIIDCWIDNIRLVYNRTSRTTQFP----------------------------DGVDVRVPGFGETFSLEFLDPSKRNVGSYFYTMVESLVGWGYTRGEDVRGAPYDWRRA---PNENGPYFLALQEMIEEMYQMYG-GPVVLVAHSMGNMYMLYFLQRQPQA----------WKDKYIQAFVSLGAPWGGVAKTLRVLASGDNNRIPVIGPLKIR-------EQQRSAVSTSW-----LLPY--NHTWSHEKVFVYTPTAN----------YTLRDYHRFFQDIGFEDG----------WFMRQDTQGLVEALV--------------------------PPGVELHCLYGTGVPTPNSFYYEN----------FPDRDPK-ICFGDGDGTVNLESVLQCQAWQS---------------RQEHKVSLQELPG----SEHIEMLANATTLAYLKRVLLEEP----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEB4-1", "uniprot_id": "PAG15_MOUSE", "id": "Q8VEB4-1", "name": "Lysosomal phospholipase A and acyltransferase", "aln": "---------------------------------------------------------------------MDRHLCTCRETQLRSGLLLPLFLLMMLADLTLP---AQR------HPPVVLVPGDL-----------------GNQLEAKLDKPKVVHYLCSKKTDSYFTLWLNLELLLPVIIDCWIDNIRLVYNRTSRATQFP----------------------------DGVDVRVPGFGETFSMEFLDPSKRNVGSYFYTMVESLVGWGYTRGEDVRGAPYDWRRA---PNENGPYFLALREMIEEMYQMYG-GPVVLVAHSMGNVYMLYFLQRQPQV----------WKDKYIHAFVSLGAPWGGVAKTLRVLASGDNNRIPVIGPLKIR-------EQQRSAVSTSW-----LLPY--NHTWSHEKVFVYTPTTN----------YTLRDYHRFFRDIGFEDG----------WFMRQDTEGLVEAMT--------------------------PPGVELHCLYGTGVPTPNSFYYES----------FPDRDPK-ICFGDGDGTVNLESVLQCQAWQS---------------RQEHRVSLQELPG----SEHIEMLANATTLAYLKRVLLEP-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCC3-1", "uniprot_id": "PAG15_HUMAN", "id": "Q8NCC3-1", "name": "Lysosomal phospholipase A and acyltransferase", "aln": "---------------------------------------------------------------------MGLHLRPYRVGLLPDGLLFLLLLLMLLADPALP---AGR------HPPVVLVPGDL-----------------GNQLEAKLDKPTVVHYLCSKKTESYFTIWLNLELLLPVIIDCWIDNIRLVYNKTSRATQFP----------------------------DGVDVRVPGFGKTFSLEFLDPSKSSVGSYFHTMVESLVGWGYTRGEDVRGAPYDWRRA---PNENGPYFLALREMIEEMYQLYG-GPVVLVAHSMGNMYTLYFLQRQPQA----------WKDKYIRAFVSLGAPWGGVAKTLRVLASGDNNRIPVIGPLKIR-------EQQRSAVSTSW-----LLPY--NYTWSPEKVFVQTPTIN----------YTLRDYRKFFQDIGFEDG----------WLMRQDTEGLVEATM--------------------------PPGVQLHCLYGTGVPTPDSFYYES----------FPDRDPK-ICFGDGDGTVNLKSALQCQAWQS---------------RQEHQVLLQELPG----SEHIEMLANATTLAYLKRVLLGP-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A862-1", "uniprot_id": "A0AB13A862_DANRE", "id": "A0AB13A862-1", "name": "", "aln": "------------------------------------------------------------------------MLPSHRLILASLQLCLLLLVVSFTEGRSLK---CPPGKVCSVRPPVVLIPGDL-----------------GNQLEAKLDKPSVVHYICYKKTEDYFTLWLNLELLVPVAIDCWIDNMRLLYNRTNHLSEPP----------------------------PGVDIRVPGFGETYSLEYLDPSKRSVGMYFFTIVQSLVDWGYTRNDDVRGAPYDWRKA---PNENKEYFLRLQQMIEEMAHKAG-GPVVLIAHSMGNMYTLYFLNHQPQA----------WKDRYIKAYVSLGPPWAGVAKTLRVMATGDNNRIPVISPLKIR-------TQQRTAVSTTW-----LLPY--AHTWPKDMVLVYTPNTT----------YTVQDYQRFFKDIDYEDG----------WAMRQDTEPLVSALQ--------------------------PPGVPVHCLYGTGIPTPQGYNYTN----------FPDTDPA-VINGDGDGTVNLISAIQCKRWKG---------------QQKQAVEWLELPG----NEHVAMLLNSTTVDYIKKVLFSP-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7L9-1", "uniprot_id": "Q9I7L9_DROME", "id": "Q9I7L9-1", "name": "Group XV phospholipase A2", "aln": "-----------------------------------------------------------------------MRLKSGVLSLLLLTTFLALGECFWPFSKWHGRNDNPSAPPEPKLSPVIFVPGDG-----------------GSQMDARLNKPNSPYLICQK-THDWYNLWLDLEQLVIPMVYCWIDNVKLYYDKVTRTTHNT----------------------------PGVETRIPGWGNPEVVEWIDPTKNSAGAYFKDIANELVKLGYIRKQNIHGAPYDFRKA---PNENQQFFIDLKQLVEDSYEANNQSAVTFISHSMGSLMTLVFLQEQTLQ----------WKAKYVKRMISLAGVWAGSFKAVKVFAMGDDLDSFALSAKILK-------AEQITHPSTAW-----LLPS--PLFWKPSEVLAMTPSRN----------YTMAQLEEFFKDLDYMTG----------WEMRKDTIRYNRNFD--------------------------PPNVELHCLYGEGIDTVERLQYKKS---------DISGETPKLIMGLGDGTVNQRSLRACKYWAG---------------YSKAPINTLALQN----VDHLHILSNPDVLKYIRTVMQQP-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40345-1", "uniprot_id": "PDAT_YEAST", "id": "P40345-1", "name": "Phospholipid:diacylglycerol acyltransferase", "aln": "MGTLFRRNVQNQKSDSDENNKGGSVHNKRESRNHIHHQQGLGHKRRRGISGSAKRNERGKDFDRKRDGNGRKRWRDSRRLIFILGAFLGVLLPFSFGAYHVHNSDSDLFDNFVNFDSLKVYLDDWKDVLPQGISSFIDDIQAGNYSTSSLDDLSENFAVGKQLLRDYNIEAKHPVVMVPGVISTGIESWGVIGDDECDSSAHFRKRLWGSFYMLRTMVMDKVCWLKHVMLDPETGLDPPNFTLRAAQGFESTDYFIAGYWIWNKVFQNLGVIGYEPNKMTSAAYDWRLAYLDLERRDRYFTKLKEQIELFHQLSG-EKVCLIGHSMGSQIIFYFMKWVEAEGPLYGNGGRGWVNEHIDSFINAAGTLLGAPKAVPALISGEMKDTIQLNTLAMYGLEKFFSRIERVKMLQTWGGIPSMLPKGEEVIWGDMKSSSEDALNNNTDTYGNFIRFERNTSDAFNKNLTMKDAINMTLSISPEWLQRRVHEQYSFGYSKNEEELRKNELHHKHWSNPMEVPLPEAPHMKIYCIYGVNNPTERAYVYKEEDDSSALNLTIDYESKQPVFLTEGDGTVPLVAHSMCHKWAQGASPYNPAGINVTIVEMKHQPDRFDIRGGAKSAEHVDILGSAELNDYILKIASGNGDLVEPRQLSNLSQWVSQMPFPM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: . . *. : ::. : : .: . :: : *:. : : . *.: : . :: . : . : : .*.**:* .. :: * :* * ::.**:* : *: * ..: :. . * *.: : *: :. : : .* ::* * . . : * :: . * .* : ::*:** . * * . **.** : * * : *: :: . : : ", "identical_positions": 36, "similar_positions": 87, "identity": "5.44%" }, { "cls_id": "homologset.agr.SGD:S000005294", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6MG13-1", "uniprot_id": "Q6MG13_RAT", "id": "Q6MG13-1", "name": "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16", "aln": "MATPAGLERWVQEELHSVLGLSERHVAQFLIGTAQRCASAEEFVQRLRDTETLDLGGPARDFALKLWSKVPRKAVVEKPARAAEREARALLEKNRSYKLLEDSE-SGEEAVARDGSSLQKKRKRRKHLRKKQQEEEE-EEEEASESGKRKTGGSKSPTEEKPASEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSD-KKAYEEAQKRLKMAEEDRKAMVPELRKKSRREYLAKREREKLEDLEAELADEEVLFGDVELSRHERRELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARATDIVEEESGAPGEEQRRWEEARLDAASLKFG-ARDAAAQEP--QYQLVLEEDETIEFVR---AAQLQGDEEPSS--GPPLSAQAQQKESIQAVRRSLPVFPFREELLTAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTKKG-MKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTS-ERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATLDTARFSAFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPP-GDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYS-CS---EEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGLTSCQG----------DYVRVRKAITSGYFYHTARLTRSG-YRTVKQQQ---TVFIHPNSSLFE------QQP-RWLLYHELVLTTKEFMRQVLEIES-SWLLEVAPHYYKAKELEDPHAKKMPKKVGKTREELG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3X8X0-1", "uniprot_id": "G3X8X0_MOUSE", "id": "G3X8X0-1", "name": "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16", "aln": "MATPAGLERWVQEELHSVLGLSERHVAQFLIGTAQRCASAEEFVQRLRDTDTLDLGGPARDFALKLWSKVPRKAVVEKPARAAEREARALLEKNRSYKLLEDSE-SGEEAVGSNGSSLQKKRKRRKHLRKKHQEDEEDEEEEVSESGKRKAGGSKSPTEEKPASEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSD-KKAYEEAQKRLKMAEEDRKAMVPELRKKSRREYLAKREREKLEDLEAELADEEVLFGDVELSRHERRELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARTVDIVEEESGAPGEEQRRWEEAQLGAASLKFG-ARDAAAQEA--KYQLVLEEDETIEFVR---AAQLQGDEEPS---GPPLSAQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTKKG-MKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTS-ERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATLDTARFSAFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPP-GDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYS-CS---EEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGLTSCQG----------DYVRVRKAITSGYFYHTARLTRSG-YRTVKQQQ---TVFIHPNSSLFE------QQP-RWLLYHELVLTTKEFMRQVLEIES-SWLLEVAPHYYKAKELEDPHAKKMPKKVGKTREELG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60231-1", "uniprot_id": "DHX16_HUMAN", "id": "O60231-1", "name": "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16", "aln": "MATPAGLERWVQDELHSVLGLSERHVAQFLIGTAQRCTSAEEFVQRLRDTDTLDLSGPARDFALRLWNKVPRKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEE---EEASEKGKKKTGGSKQQTE-KPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSD-KKAYEEAQKRLKMAEEDRKAMVPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFG-ARDAASQEP--KYQLVLEEEETIEFVR---ATQLQGDEEPS---APPTSTQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKG-MKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTS-ERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPP-GDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYS-CS---EEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGLSSCQG----------DYIRVRKAITAGYFYHTARLTRSG-YRTVKQQQ---TVFIHPNSSLFE------QQP-RWLLYHELVLTTKEFMRQVLEIES-SWLLEVAPHYYKAKELEDPHAKKMPKKIGKTREELG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIZ3-1", "uniprot_id": "Q9VIZ3_DROME", "id": "Q9VIZ3-1", "name": "RNA helicase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MSGKNRKRTASSSSSGE-EPDSE------EESRLKDLQERDEFASRLKKRDDDRTRNVVDSTGGRRAIEEATKRLKLEHEDRDKIVPHLRLQSRRQYLEKRKDDKVAELEADILDDEYLFDESVLTKREKEEREYKKQLLNIAKEHEKAR---ELERIQRYNMPQDLKKGERSEYVEVDEFEKQPNSEQKKWEAEQLASARFHFG-AKDAKAEE---EYELLLDD--QIDFIQ---ALTLDGSREKSSSRQPELTEKERKRLTLDETRRSLPVYPFKEDLIAAVKEHQVLIIEGETGSGKTTQVPQYLVEAGFTKDK-KMIGCTQPRRVAAMSVAARVAEEMGVKLGNEVGYSIRFEDCTS-DRTILKYMTDGTLHREFLSEPDLASYSVMIIDEAHERTLHTDILFGLVKDIARFRPELKLLISSATLDAEKFSAFFDDAPIFRIPGRRYPVDIFYTKAPEADYIDACCVSVLQIHATQPL-GDILVFLTGQDEIETCQEVLHDRVKRLGSKIRELIVIPVYANLPSDMQAKIFEPTPPNARKVILATNIAETSLTIDNIIYVIDPGFAKQNNFNSRTGMESLMVVPISKASANQRAGRAGRTAPGKCFRLYTAWAYKHELEDNTVPEIQRINLGNAVLMLKALGINDLIHFDFLDPPPHETLVLALEQLYALGALNHHGELTKLGRRMAEFPVDPMMGKMLLASEKYK-CS---EEMVTIAAMLSVNSAIFYRPKDKIIHADTARKNFNHMHGDHLSLLQVYNQWAETDYSTQWCYENFIQYRSMKRARDVREQLVGLMQRVEIDMVSCLP----------ETVNVRKAATAGYFYHVARLSKGGHYKTIKHNQ---TVMIHPNSSLFE------ELP-RWVLYHELVFTSKEYMRQVIEIES-KWLLEVAPHYYKAKELEDSTNKKMPKVAGRAEMAQ-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20095-1", "uniprot_id": "PRP2_YEAST", "id": "P20095-1", "name": "Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MSSITSETGKRRVKRTY----------------EVTRQNDNAVRIEPSSLGEEEDKEAKD------------KNSALQLKRSRYDPNKVFSNTNQGPEKNNLK---GEQLGSQKKSSKYDEKITSNNELTTK-------KGLLGDSENETKYAS------SNSKFNVEVTHKIKNAKEIDKINR--------QRMWEEQQLRNAMAGQSDHPDDITLEGSDKYDYVFDTDAMIDYTNEEDDLLPEEKLQYEARLAQALETEEKRILTIQEARKLLPVHQYKDELLQEIKKNQVLIIMGETGSGKTTQLPQYLVEDGFTDQGKLQIAITQPRRVAATSVAARVADEMNVVLGKEVGYQIRFEDKTTPNKTVLKYMTDGMLLREFLTDSKLSKYSCIMIDEAHERTLATDILIGLLKDILPQRPTLKLLISSATMNAKKFSEFFDNCPIFNVPGRRYPVDIHYTLQPEANYIHAAITTIFQIHTTQSLPGDILVFLTGQEEIERTKTKLEEIMSKLGSRTKQMIITPIYANLPQEQQLKIFQPTPENCRKVVLATNIAETSLTIDGIRYVIDPGFVKENSYVPSTGMTQLLTVPCSRASVDQRAGRAGRVGPGKCFRIFTKWSYLHELELMPKPEITRTNLSNTVLLLLSLGVTDLIKFPLMDKPSIPTLRKSLENLYILGALNSKGTITRLGKMMCEFPCEPEFAKVLYTAATHEQCQGVLEECLTIVSMLHETPSLFIGQK-----RDAAASVLSEVESDHILYLEIFNQWRNSKFSRSWCQDHKIQFKTMLRVRNIRNQLFRCSEKVGLVEKNDQARMKIGNIAGYINARITRCFISGFPMNIVQLGPTG-YQTMGRSSGGLNVSVHPTSILFVNHKEKAQRPSKYVLYQQLMLTSKEFIRDCLVIPKEEWLIDMVPQIFK--DLIDDKTNRGRR----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ..:::. : * * :* * :. .:.*.: . ::: :** . * . :... . ..:: * ::: . : . :* : .: *: : * : : .* . * .:::: : ::. *: ** :* * . * : * :*: ::: *:: . : . : . : :: ::: .*: ***. ::::*: : ::***** **********:****.* *:*.. *. ******** ******* **.* **:****.***** *: ::*:*:***** * ****::..*:.** :::******** ****:**:**: ** **:*::***::: :** ***:.*:*.:****:****.** ***:*:.*. .:::***.**. **********:*** *.: :***: ::::: *:*****.: * :**:*** ..***::***********:.* **:**** *::.: . *** .* ..* *:**.:********...*****::* *:* **** . *** * .*.*.**:* :**: **::* ::* *. ** :**:** ***** * :* *: *.*:* :* :.*:: :: .:. *. ** :*:.:** . ::* * * * : .**: *:::.** :: :* .** :: :*:::* *.*::*:** ::* : . .: :. :*: : .:* * *:*: :.. .* :**.* ** : * :::**::*::*:**::*: : * . .**:::.*: :* :* * :: : ", "identical_positions": 314, "similar_positions": 281, "identity": "28.97%" }, { "cls_id": "homologset.agr.SGD:S000005295", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91YL3-1", "uniprot_id": "UCKL1_MOUSE", "id": "Q91YL3-1", "name": "Uridine-cytidine kinase-like 1", "aln": "MAAPPASMSAAPSPLQSAVAPDVPGRQAEQNETACEDRSNAGTLDRLLP---PVGTGRSPRKRTTSQCKSEPPLLRTSKRTIYTAGRPPWYNEHGTQSKEAFAIGLGGGSASGKTTVARMIIEALDVPWVVLLSMDSFYKVLTQQQQEQAACNNFNFDHPDAFDFDLIISTLKKLKQGRSVQVPIYDFTTHSRKKD-WKTLYGANVIIFEGIMAFADKTLLELLDMKIFVDTDSDIRLVRRLRRDISERGRDIEGVIKQYNKFVKPAFDQYIQPTMRLADIVVPRGSGNTVAIDLIVQHVHSQLEER---ELSVR-AALASAHQCHPLPQTLSVLKSTPQVRGMHTIIRDKETSRDEFIFYSKRLMRLLIEHALSFLPFQDCTVQTPQGQDYV-GKCYAGKQITGVSILRAGETMEPALRAVCKDVRIGTILIQTNQLTGEPELHYLRLPKDISDD-HVILMDCTVSTGAAAMMAVRVLLDHDVPEDKIFLLSLLMAEMGVHSVAYAFP-RVRIIT--TAVDKRVNDLFRIIPGIGNFGDRYFGTDAVPDGSDDDEAATVG-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GA89-1", "uniprot_id": "A0A8I6GA89_RAT", "id": "A0A8I6GA89-1", "name": "Uridine-cytidine kinase", "aln": "MAAPPGSAGAAPSPLQSTVTPDVPGRPAEQNETSCEDRSNAGSLDRLLP---PVGTGRSPRKRTTSQCKSEPPLLRTSKRTIYTAGRPPWYNEHGTQSKEAFAIGLGGGSASGKTTVARMIIEALDVPWVVLLSMDSFYKVLTQQQQEQAACNNFNFDHPDAFDFDLIISTLKKLKQGRSVQIPIYDFTTHSRKKD-WKTLYGANVIIFEGIMAFADKTLLELLDMKIFVDTDSDIRLVRRLRRDISERGRDIEGVIKQYNKFVKPAFDQYIQPTMRLADIVVPRGSGNTVAIDLIVQHVHSQLEER---KLRWDMAALASAHQCHPLPQTLSVLKSTPQVRGMHTIIRDKETSRDEFIFYSKRLMRLLIEHALSFLPFQDCTVQTPQGQDYV-GKCYAGKQITGVSILRAGETMEPALRAVCKDVRIGTILIQTNQLTGEPELHYLRLPKDISDD-HVILMDCTVSTGAAAMMAVRVLLDHDVPEDKIFLLSLLMAEMGVHSVAYAFP-RVRIIT--TAVDKRVNDLFRIIPGIGNFGDRYFGTDAVPDGSDDDEVTSVG-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NWZ5-1", "uniprot_id": "UCKL1_HUMAN", "id": "Q9NWZ5-1", "name": "Uridine-cytidine kinase-like 1", "aln": "MAAPPARADADPSPTSPPTARDTPGRQAEKSETACEDRSNAESLDRLLP---PVGTGRSPRKRTTSQCKSEPPLLRTSKRTIYTAGRPPWYNEHGTQSKEAFAIGLGGGSASGKTTVARMIIEALDVPWVVLLSMDSFYKVLTEQQQEQAAHNNFNFDHPDAFDFDLIISTLKKLKQGKSVKVPIYDFTTHSRKKD-WKTLYGANVIIFEGIMAFADKTLLELLDMKIFVDTDSDIRLVRRLRRDISERGRDIEGVIKQYNKFVKPSFDQYIQPTMRLADIVVPRGSGNTVAIDLIVQHVHSQLEER---ELSVR-AALASAHQCHPLPRTLSVLKSTPQVRGMHTIIRDKETSRDEFIFYSKRLMRLLIEHALSFLPFQDCVVQTPQGQDYA-GKCYAGKQITGVSILRAGETMEPALRAVCKDVRIGTILIQTNQLTGEPELHYLRLPKDISDD-HVILMDCTVSTGAAAMMAVRVLLDHDVPEDKIFLLSLLMAEMGVHSVAYAFP-RVRIIT--TAVDKRVNDLFRIIPGIGNFGDRYFGTDAVPDGSDEEEVAYTG-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B8Y1-1", "uniprot_id": "A0A8M2B8Y1_DANRE", "id": "A0A8M2B8Y1-1", "name": "Uridine-cytidine kinase", "aln": "MSAVCGDG------------RDSAMECGEKSSARCTSGGAEDSLDRLLP---TVNTSLSPRKRTTSQCKSEPPLLRTSKRTIYTAGRPPWYNEHGTQSKEAFVIGLCGGSASGKTTVARKIIEALDVPWVVLLSMDSFYKVLTSEQQLQAASNDYNFDHPDAFDFVLLVHTLRKLKQGKSVKIPVYDFTTHGRQKE-WKTVYGASVIIFEGIMSFADKELLKLLDMKIFVDTDSDIRLVRRLRRDITERGRDIEGVIKQYNKFVKPAFEQYIEPTMRLADIVVPRGGGNMVAIDLIVQHVHSQLEER---KLRWDMAALASAHQAQPLPQTLSVLESTPQVRGMHTIIRNKDTNRDEFIFYSKRLMRLLIERALSFLPSQVHIVQTPQGEDYE-GRIFHGKRITGVSILRAGETMEPALRAVCKDVRIGKILIQTNQDTGEPELHYLRLPKDISED-HVILMDCTVSTGAAAMMAIRVLLDHDVQEEKILLVSLLMAEMGVHSVAYAFP-QVKIIT--TAVDKKVNDLFHIIPGIGNFGDRYFGTDAPTDWSDDDMDEPSC-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PQ05-1", "uniprot_id": "A0A8M9PQ05_DANRE", "id": "A0A8M9PQ05-1", "name": "Uridine-cytidine kinase", "aln": "MAMTTSQND-------VQVQQKEEGEEDEQSMSRSD--SGEDSLDGLLRNRCPLTPSISPRKRTTSQSKTEPPLLRTNKRTIYTAGRPPWYNVTGTTFKEAFVIGLCGGSASGKTTVANKIIEALDVPWVVLLSMDSFYKVLSKDAQELAAKNEYNFDHPDAFDFELLVTVLRKLKKGKSIKVPVYDFTTHSRRKE-WKTVYGANVVIFEGILAFANKELLKLLDMKVFVDTDSDIRLVRRLKRDITDRGRDISGVIKQYNKFVKPAFEQYIEPTVQVADIVVPRGGENFVALDLIVQHVHSQLEKR---KLRWDISALASAHQGQPLPKTLSVMESTPQVRGMHTIIRNKETSRDEFIFYSKRLMRLLIEHALSFLPLKPVTVETPQGTVYE-GKRLSGKRITGVSILRAGETMEQALMAVCKDIRLGKILIQTNHDTGEPELHYLRLPKDISED-YVILMDSTVSTGAAALMAVRVLLDHDVQEDKIFLLSLLMAEMGVHSVAYAFP-KVRIIT--TAVDKKVNDEFHIIPGIGNFGDRYFGTDAPSDCYESDEGMDY------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BF24-1", "uniprot_id": "A0A8M2BF24_DANRE", "id": "A0A8M2BF24-1", "name": "Uridine-cytidine kinase", "aln": "MEDRRQAFTADMSTLPGYTGARISGCWALRTD---GGGSGEDSLDRLLP---PVSTS---RRKSSNLGKTEPPLLRTGTRTIYTAGRPPWYNEHGAQFKEAFVIGLCGGSASGKTTVANKIIEALDVPWVVLLSMDSFYKVLSAEEQALAASNDYNFDHPGAFDFELLVTTLRKLKQGKSVKIPVYDFTTHGRQKE-WKNVYGASVIIFEGILSFADKELLQLMDMKIFVDTDSDIRLVRRLRRDITERGRDIEGVIKQYNKFVKPAFEQYIEPTMRLSDIVVPRGGGNMVAIDLIVQHVHSQLEER---EISVR-ALLATAHQSQPLPQTLSVLESTPQVRGLHTIIRNKDTSRDEFIFYSKRLMRLLIEHALSFLPAKPCTIQTPQGQEYK-GCRFGGKGITGVSILRAGETMEPALRAVCKDVRIGKILIQTNLDSGEPELHYLRLPRDISED-HVILMDSTVSTGAAAMMAVRVLLDHDVQEEQIVLVSLLMAELGVHSIAYAFP-RVKIIT--TAVDKSLDDLLHVIPGIGDFGDRYFGTDGSSSWSEEDQQEPLSCSSEV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P27515-1", "uniprot_id": "URK1_YEAST", "id": "P27515-1", "name": "Uridine kinase", "aln": "-----------------------------MSHRIAPSKERSSSFISILD-------------DETRDTLKANAVMDGEVDVKKTKGKSSRYIPP---WTTPYIIGIGGASGSGKTSVAAKIVSSINVPWTVLISLDNFYNPLGPEDRARAFKNEYDFDEPNAINLDLAYKCILNLKEGKRTNIPVYSFVHHNRVPDKNIVIYGASVVVIEGIYALYDRRLLDLMDLKIYVDADLDVCLARRLSRDIVSRGRDLDGCIQQWEKFVKPNAVKFVKPTMKNADAIIPSMSDNATAVNLIINHIKSKLELKSNEHLRELIKLGSSPSQDVLNRNIIHELPPTNQVLSLHTMLLNKNLNCADFVFYFDRLATILLSWALDDIPVAHTNIITPGEHTMENVIACQFDQVTAVNIIRSGDCFMKSLRKTIPNITIGKLLIQSDSQTGEPQLHCEFLPPNIEKFGKVFLMEGQIISGAAMIMAIQVLLDHGIDLEKISVVVYLATEVGIRRILNAFDNKVNIFAGMIISREKLQNHQYKWALTRFFDSKYFGCD--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: :* : . .:: . * *:.. * . .: **: *.*.****:** *:.:::***.**:*:*.**: * : : * *:::**.*.*::: * : :**:*: ::*:*.*. *.* : :***.*:::*** :: :: **.*:*:*::**:* *: *.*** *** .****:.* *:*::***** ::::**:: :* ::* . * .*::**::*::*:** : .: ::. * . : : .* ** .:**:: :*: . :*:** .** :*:. **. :* : ** . :*.*.*:*:*: : :* . :: :*.:***:: :***:** ** :*.. *:**: : :*** :**::*****.: ::* :: * :*:*:: : ** :*.*:: : ::: . *..:*** * ", "identical_positions": 149, "similar_positions": 170, "identity": "26.33%" }, { "cls_id": "homologset.agr.SGD:S000005296", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ES88-1", "uniprot_id": "S13A2_MOUSE", "id": "Q9ES88-1", "name": "Solute carrier family 13 member 2", "aln": "--------------------------------MATCWQALWAYRSYLIVLCLPIFLLPLPLIVQTKEAYCAYSIILMALLWCTEALPLAVTALFPIILFPLMGIMEASKVCLEYFKDTNILFVG-----GLMVAIAVEHWNLHKRIALGVLLIIGVRPALLLLGFMLVTAFLSMWISNTATTAMMLPIGYAVLEQLQGSQK---DVEEGNSN---------------PSFELQEA-----------SPQKEETKLD----------------------NGQA---VSVSSEPRAQKTKEHHR-FSQGLSLCICYSASIGGIATLTGTTPNLVLQGQVNSIFPENS-------------NVVNFASWFGFAFP-TMVILLLLAWLWLQVLFLGVNFRKN-FGFGEGEEERK-QAAFQVIKTQHRLLGPMSFAEKAVTFLFVLLVVLWFTREPGFFPGWGDTAFANKKGQSMVSDGTVAIFISLIMFIIPSKIPGLTEDPKKPGKLKA-------------------PPAILTWKTVNDKMPWNILILLGGGFALAKGSEESGLSKWLGDKLTPLQHVPPSATVLILSLLVAIFTECTSNVATTTLFLPILASMAQAIC------------------------------------------------LHPLYVMLPCTLAASLAFMLPVATPPNAIVFSFGGLKVSDMARAGFLLNIIGVLTITLSINSWSIPIFK-LDTFPTWAYSN-TSQCLLNPPNSTVPGH----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P70545-1", "uniprot_id": "S13A2_RAT", "id": "P70545-1", "name": "Solute carrier family 13 member 2", "aln": "--------------------------------MATCWPALWAYRFYLIVLCLPIFLLPLPLIVQTKEAYCAYSIILMALLWCTEALPLAVTALFPIVLFPLMGIMDASEVCIEYFKDTNILFVG-----GLMVAIAVEHWNLHKRIALQVLLIIGVRPALLLLGFMLVTAFLSMWISNTATTAMMVPIGHAVLEQLQGSKK---DVEGGNNN---------------PTFELQEE-----------CPQKEVTKLD----------------------NGQP---VSAPSEPRTQKTQEHHR-FSQGLSLCICYSASIGGIATLTGTTPNLVLQGQVNSLFPQNG-------------NVVNFASWFGFAFP-TMIILLLLAWLWLQVLFLGVNFRKN-FGFGEGEEERK-QAAFQVIKTQYRLLGPMSFAEKTVTVLFVLLVVLWFTREPGFFPGWGDTVFANEKGQSMASDGTVAIFISLVMFIIPSKIPGLMQDPKKPGKLKA-------------------PPAILTWKTVNDKMPWNIVILLGGGFALAKGSEQSGLSEWLGDKLTPLQHIPPSATAVILCLLIAIFTECTSNVATTTLFLPILASMAQAIC------------------------------------------------LHPLYVMLPCTLAASLAFMLPVATPPNAIVFSFGGLKVSDMARAGFLLNIIGVLAITLSINSWSIPIFK-LDTFPSWAHSN-TSQCLLNPSNSTVPGGL---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13183-1", "uniprot_id": "S13A2_HUMAN", "id": "Q13183-1", "name": "Solute carrier family 13 member 2", "aln": "--------------------------------MATCWQALWAYRSYLIVFFVPILLLPLPILVPSKEAYCAYAIILMALFWCTEALPLAVTALFPLILFPMMGIVDASEVAVEYLKDSNLLFFG-----GLLVAIAVEHWNLHKRIALRVLLIVGVRPAPLILGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHSSQAS-SNVEEGSNN---------------PTFELQEP-----------SPQKEVTKLD----------------------NGQALPVTSASSEGRAHLSQKHLH-LTQCMSLCVCYSASIGGIATLTGTAPNLVLQGQINSLFPQNG-------------NVVNFASWFSFAFP-TMVILLLLAWLWLQILFLGFNFRKN-FGIGEKMQEQQ-QAAYCVIQTEHRLLGPMTFAEKAISILFVILVLLWFTREPGFFLGWGNLAFPNAKGESMVSDGTVAIFIGIIMFIIPSKFPGLTQDPENPGKLKA-------------------PLGLLDWKTVNQKMPWNIVLLLGGGYALAKGSERSGLSEWLGNKLTPLQSVPAPAIAIILSLLVATFTECTSNVATTTIFLPILASMAQAIC------------------------------------------------LHPLYVMLPCTLATSLAFMLPVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAINSWGIPLFS-LHSFPSWAQSNTTAQCLPSLANTTTPSP----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q67BT3-1", "uniprot_id": "S13A5_MOUSE", "id": "Q67BT3-1", "name": "Na(+)/citrate cotransporter", "aln": "--------------------------------MDSAKTCVTKFKSFAILLFTPILMLPLVILIPDKFARCAYVIVIMAVYWCTDVIPVAVTSLLPVLLFPLLKVLDSKQVCIQYMKDTNMLFLG-----SLIVAVAVERWKLHKRVALRMLLFVGTKPSRLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMIAANT-----AVEASL---------------GTLELLD--------------KNKTSELP----------------------GSQV---VFEDPNVQEQEDEETKN-MYKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMQELFPDSK-------------DVLNYASWFGFAFP-NMVMMLVLAWLWLQCLYMRHNLKKTCICCGEKKRDTE-KIAYKVLNEEYQKLGSLSYPECNVLFCFTLLVILWFSRDPGFMPGWLSFAWVEG-NTVHITDATVAIFVAILLFIIPSQKPKFNFSSQTEEERKTPFY----------------PPALLDWKVAQEKVPWDIVLLLGGGFAMAKGCETSGLSKWMAAQMEPLRLVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMARSIG------------------------------------------------IHPLYVMIPCTMSASLAFMLPVATPPNAIVFAYGHLRVVDMMKTGLIMNFVGILSVFLSVNTWGRAMFN-LDNFPDWANSTSVNT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CJ44-1", "uniprot_id": "S13A5_RAT", "id": "Q8CJ44-1", "name": "Na(+)/citrate cotransporter", "aln": "--------------------------------MASAKTYVTKFKSFVILFFAPILLLPLIILVPDKFARCAYVIILMAIYWCTDVIPVAITSLLPVLLFPLLKVLDSKQVCVQYMTDTNMLFLG-----SLIVATAVERWELHKRIALRMLLFVGTKPSRLMLGFMFVTAFLSMWISNTATTAMMIPIVEAMLEQMVATNV-----AVDASQ---------------RTMELLD--------------KNKASELP----------------------GSQV---VFEDPSVQKQEDEETKN-MYKAMNLCVCYAASIGGTATLTGTGPNVVLLGQMQELFPDSK-------------DVMNFASWFAFALP-NMLLMLVMAWLWLLCFYMRPNLKKTCICCGRKKKDTE-KIASKVLYEEYRKLGPLSYAECNVLFCFGLLIILWFSRDPGFMPGWLSIAWIEG-NTKHVTDATVAIFVAILLFIVPSQKPKFNFSRQTEEERKTPFY----------------PPPLLNWKVTQEKVPWGIVLLLGGGFAMAKGCETSGLSEWMARQMEPLSSVRPAIITLILSCIVAMTTECTSNVATTTLFLPIFASMARSIG------------------------------------------------IHPLYVMIPCTLSASLAFMLPVATPPNAIVFAYGHLKVIDMVKTGLVMNILGIASVFLSVNTWGRAVFN-LDKFPDWANLTHINT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86YT5-1", "uniprot_id": "S13A5_HUMAN", "id": "Q86YT5-1", "name": "Na(+)/citrate cotransporter", "aln": "--------------------------------MASALSYVSKFKSFVILFVTPLLLLPLVILMPAKFVRCAYVIILMAIYWCTEVIPLAVTSLMPVLLFPLFQILDSRQVCVQYMKDTNMLFLG-----GLIVAVAVERWNLHKRIALRTLLWVGAKPARLMLGFMGVTALLSMWISNTATTAMMVPIVEAILQQMEATSA-----ATEAG------------------LELVD--------------KGKAKELP----------------------GSQV---IFEGPTLGQQEDQERKR-LCKAMTLCICYAASIGGTATLTGTGPNVVLLGQMNELFPDSK-------------DLVNFASWFAFAFP-NMLVMLLFAWLWLQFVYMRFNFKKS-WGCGLESKKNE-KAALKVLQEEYRKLGPLSFAEINVLICFFLLVILWFSRDPGFMPGWLTVAWVEG-ETKYVSDATVAIFVATLLFIVPSQKPKFNFRSQTEEERKTPFY----------------PPPLLDWKVTQEKVPWGIVLLLGGGFALAKGSEASGLSVWMGKQMEPLHAVPPAAITLILSLLVAVFTECTSNVATTTLFLPIFASMSRSIG------------------------------------------------LNPLYIMLPCTLSASFAFMLPVATPPNAIVFTYGHLKVADMVKTGVIMNIIGVFCVFLAVNTWGRAIFD-LDHFPDWANVTHIET-----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91Y63-1", "uniprot_id": "S13A3_MOUSE", "id": "Q91Y63-1", "name": "Na(+)/dicarboxylate cotransporter 3", "aln": "-----------------------------MAALAALAKKVWSARRLLVLLLVPLALLPILFALPPKEGRCLYVILLMAVYWCTEALPLSVTALLPIILFPFMGILPSSKVCPQYFLDTNFLFLS-----GLIMASAIEEWNLHRRIALKVLMLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIASAILKSLFGQREARKDLPREGDE---------------STAAVQGN-----------GLRTVPTEMQFLASSE----------------GGHTEDAEAPMELPDDSKEEEHRRNIWKGFLISIPYSASIGGTATLTGTAPNLILLGQLKSFFPQC--------------DVVNFGSWFIFAFP-LMLLFLLVGWLWISFLYGGMSWRSWRKKKSKIRADAE-DQAKAVIQEEFQNLGPIKFAEQAVFILFCTFAILLFSRDPKFIPGWAS-LFAPG----FVSDAVTGVAIVTILFFFPSQKPSLKWWFDFKAPNSE-------------------TEPLLSWKKAQETVPWNIILLLGGGFAMAKGCEESGLSAWIGGQLHPLEHVPPLLAVLLITVVIAFFTEFASNTATIIIFLPVLAELAIRLH------------------------------------------------VHPLYLMIPGTVGCSYAFMLPVSTPPNSIAFSTGHLLVKDMVRTGLLMNLMGVLLLSLAMNTWAQTIFQ-LGTFPDWANTHAANATALPPALTNNTVQTF--------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z0Z5-1", "uniprot_id": "S13A3_RAT", "id": "Q9Z0Z5-1", "name": "Na(+)/dicarboxylate cotransporter 3", "aln": "-----------------------------MAALAALAKKVWSARRLLVLLLVPLALLPILFALPPKEGRCLYVILLMAVYWCTEALPLSVTALLPIILFPFMGILPSSKVCPQYFLDTNFLFLS-----GLIMASAIEERNLHRRIALKVLMLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIASAILKSLFGQRDTRKDLPREGED---------------STAAVRGN-----------GLRTVPTEMQFLASSE----------------GGHAEDVEAPLELPDDSKEEEHRRNIWKGFLISIPYSASIGGTATLTGTAPNLILLGQLKSFFPQC--------------DVVNFGSWFIFAFP-LMLLFLLVGWLWISFLYGGMSWRGWRKKNSKLQDVAE-DKAKAVIQEEFQNLGPIKFAEQAVFILFCLFAILLFSRDPKFIPGWAS-LFAPG----FVSDAVTGVAIVTILFFFPSQKPSLKWWFDFKAPNSE-------------------TEPLLSWKKAQETVPWNIILLLGGGFAMAKGCEESGLSAWIGGQLHPLEHVPPLLAVLLITVVIAFFTEFASNTATIIIFLPVLAELAIRLH------------------------------------------------VHPLYLMIPGTVSCSYAFMLPVSTPPNSIAFSTGHLLVKDMVRTGLLMNLMGVLLLSLAMNTWAQAIFQ-LGTFPDWANTHAANVTALPPALTNNTVQTL--------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHI4-1", "uniprot_id": "S13A1_MOUSE", "id": "Q9JHI4-1", "name": "Solute carrier family 13 member 1", "aln": "---------------------------------MKLLNYALVYRRFLLVVFTILVFLPLPLIIRTKEAQCAYILFVIAIFWITEALPLSITALLPGLMFPMFGIMRSSQVASAYFKDFHLLLIG-----VICLATSIEKWNLHKRIALRMVMMVGVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIVEAVAQQIISAEAEAEATQMTYFN-----------ESAAHGLDIDET-----------VIGQETNEKKEKTKPAPGSSHDKGK------VSRKMETEKNAV--TGAKYRSRKDHMMCKLMCLSVAYSSTIGGLTTITGTSTNLIFSEHFNTRYPDC--------------RCLNFGSWFLFSFP-VALILLLLSWIWLQWLYLGFDFK-MFKCGKT-KTLKE-KACAKVIKQEYEKLGPMRYQEIVTLVIFIVMALLWFSRDPGFVTGWSV-LFSEY--PGYVTDSTVALVAGILFFLIPAKKVTKMTS-AGEIIAFDYT-------------------PLITWKEFQSFMPWDIAILVGGGFALADGCQVSGLSNWIGSKLSPLGSLPVWLIILISSLIVTSLTEVASNPATITILFPILSPLAEAIQ------------------------------------------------VNPLQILLPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNILGVAVVMLGMFTWIEPMFN-LHEYPSWASNFVNQTMP---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07782-1", "uniprot_id": "S13A1_RAT", "id": "Q07782-1", "name": "Solute carrier family 13 member 1", "aln": "---------------------------------MKLLNYAFVYRRFLLVVFTVLVLLPLPLIIRSKEAECAYILFVIATFWITEALPLSITALLPGLMFPMFGIMSSTHVASAYFKDFHLLLIG-----VICLATSIEKWNLHKRIALRMVMMVGVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIVEAVAQQITSAEAEAEATQMTYFN-----------ESAAQGLEVDET-----------IIGQETNERKEKTKPALGSSNDKGK------VSSKMETEKNTV--TGAKYRSKKDHMMCKLMCLCIAYSSTIGGLTTITGTSTNLIFSEHFNTRYPDC--------------RCLNFGSWFLFSFP-VAVILLLLSWIWLQWLFLGFNFKEMFKCGKT-KTLKE-KACAEVIKQEYEKLGPMRYQEIVTLVIFIVMALLWFSRDPGFVTGWSV-LFSEY--PGYVTDSTVALVAGILFFLIPAKKLTKMTS-TGDIIAFDYS-------------------PLITWKEFQSFMPWDIAILVGGGFALADGCQVSGLSSWIGSKLSPLGSLPVWLIILISSLIVTSLTEVASNPATITILFPILSPLAEAIH------------------------------------------------VNPLHILLPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNILGVAVVMLGMFTWIEPMFN-LHEYPSWAPDIVNQTMP---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BZW2-1", "uniprot_id": "S13A1_HUMAN", "id": "Q9BZW2-1", "name": "Solute carrier family 13 member 1", "aln": "---------------------------------MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTALLPSLMLPMFGIMPSKKVASAYFKDFHLLLIG-----VICLATSIEKWNLHKRIALKMVMMVGVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFN-----------GSTNHGLEIDES-----------VNGHEINERKEKTKPVPGYNNDTGK------ISSKVELEKNSG--MRTKYRTKKGHVTRKLTCLCIAYSSTIGGLTTITGTSTNLIFAEYFNTRYPDC--------------RCLNFGSWFTFSFP-AALIILLLSWIWLQWLFLGFNFKEMFKCGKT-KTVQQ-KACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSRDPGFVPGWSA-LFSEY--PGFATDSTVALLIGLLFFLIPAKTLTKTTP-TGEIVAFDYS-------------------PLITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLMVTSLTEVASNPATITLFLPILSPLAEAIH------------------------------------------------VNPLYILIPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFD-LYTYPSWAPAMSNETMP---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TJ70-1", "uniprot_id": "A0AB32TJ70_DANRE", "id": "A0AB32TJ70-1", "name": "", "aln": "---------------------------------MRRLRCSWSALKPLIIISTPLAILPLPLVIKTKEAECAYVLILMAVYWMTEVLPLSVTALIPALLFPLFGIMKSSQVASQYFKDFHLLLLG-----VICLATSIEKWGLHRRIALRLVTGLGVNPGMLMLGFMVGCAFLSMWLSNTSTVAMVMPIVEAVIQQVLSASEEANKDHKGALN-----------GISNPALQLEDI-----------EAQHDQSE---KIKSIEAGITEPEP------TSEEHETAKAPTPPYSGKYRTREDHMMCKGLSLCIAYSSSIGGLTTLSGTSTNLIFAEYIYQYYPEC--------------TIVNFGNWFVLCLP-ICIIMLILSWLFLHWMYLGSNFR-ASLCSRQ-RTEKE-KITARVLRDHYNSLGPISWQEIVTLIIFILMAILWFTRNPGFMPGWSS-LFSDN--PGYATDATVALLLGFLFFLLPSHKLNADHYGTTTLKTFSMIGGALSAFLLMIYIFIHLTEALITWKDFQACMPWEISLLVGGGFALAEGTKISGLSSWVAELLTPLGSLPPLATVTIACLIVTSITEVASNAATMTIFLPILAPLAEAIG------------------------------------------------VNPLYMLIPTALAVSFSFLLPVSNPPNAIVFTYGHLTSMDMVKAGLGVNVIGILTVLLALTTWGTPLLK-LDTYPDWAPVVNSTGV----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9UKG4-1", "uniprot_id": "S13A4_HUMAN", "id": "Q9UKG4-1", "name": "Solute carrier family 13 member 4", "aln": "---------------------------------MGLLQGLLRVRKLLLVVCVPLLLLPLPVLHPSSEASCAYVLIVTAVYWVSEAVPLGAAALVPAFLYPFFGVLRSNEVAAEYFKNTTLLLVG-----VICVAAAVEKWNLHKRIALRMVLMAGAKPGMLLLCFMCCTTLLSMWLSNTSTTAMVMPIVEAVLQELVSA--EDEQLVAGNSNTEEAEPISLDVKNSQPSLELIFVNEESNADLTTLMHNENLNGVPSITNPIKTANQHQGKKQHPSQEKPQVLTPSPRKQKLNRKYRSHHDQMICKCLSLSISYSATIGGLTTIIGTSTSLIFLEHFNNQYPAA--------------EVVNFGTWFLFSFP-ISLIMLVVSWFWMHWLFLGCNFKETCSLSKKKKTKRE-QLSEKRIQEEYEKLGDISYPEMVTGFFFILMTVLWFTREPGFVPGWDS-FFEK---KGYRTDATVSVFLGFLLFLIPAKKP---CFGK--KNDGENQEHSLG------------TEPIITWKDFQKTMPWEIVILVGGGYALASGSKSSGLSTWIGNQMLSLSSLPPWAVTLLACILVSIVTEFVSNPATITIFLPILCSLSETLH------------------------------------------------INPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNVIGLVIVMVAINTWGVSLFH-LDTYPAWARVSNITDQA---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BBY3-1", "uniprot_id": "A0A8M2BBY3_DANRE", "id": "A0A8M2BBY3-1", "name": "", "aln": "--------------------------MRLEGARMDLIKKLWTARKLILVVMIPLSLLPLPLIHPCSESSCAYVLIVTAVYWVSEAVPLGAAALVPAFLYPLFGVLKSSEVASEYFKDTTLLLMG-----VICLAASIEKWNLHKRIALRMVMIAGAKPGMLVLGFMCCTVFLSMWLSNTSTTAMVMPIAEAVLQQLICTGIADSQEDSQDLTQDEESDKEENLESSKNHLELLDCKNEKNE---VCMMNEELNGLS--LKPGFGPNFSRESNGYLPEAPISIPVPKKPKIRRDSLYPTKRDHMICKCLTLSITYAATIGGLITITGTSTNLIFAEQFNNRYPEA--------------KVINFGTWFIFSLP-IALIMLILTWIWLHFLFLGCNFRETCSLSKKRKTRRE-ILSEKRIHEEYQKLGPISYPEVVTGIFFILMTVLWFTREPGFVPGWTS-LFEK---KGYRTDATVSVLLGFLLFLIPARKPWPSAFSSQSKDDEDEDEEQDP------------LAPMITWKDFQRLMPWEIVILVGGGYALAAGCKVSGLSMWIGRQLEPMSGLPPWAVTLLACLLVSAVTEFASNPATLTVFLPILSALSETLQ------------------------------------------------MNPLHTLIPATMCVSFGVMLPVGNPPNAIVFSYGHVQISDMVKAGFGVNLIGVFVVMLAILTWGEPLFH-LSQFPTWAAMRNVTGSL---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1JIQ7-1", "uniprot_id": "E1JIQ7_DROME", "id": "E1JIQ7-1", "name": "Protein I'm not dead yet 2", "aln": "MG-------------------DADGKIGGGQAVKRCCGFHWRGKATAMIPLITLPIMIYGVLENNLAFQCMYLVANMALFWITEAIPLYLTALFPVVFLPLFGILTSEKVCSFYFSDTVVMFIG-----GLLIALAIEYSNLHQRIALNTILIVGCSPRRLHFGLVMVTCFISLWISNSAATAMMCPIVKAVLNEMETQNIFAIYKTQEEEPVE--------------------------------------------------------------------------------EGDPPHPSTISMAFYFGIAYSSSIGGCGTLIGTGTNLTYKGLYDTRFPNSD-------------EKIDFPIFMAYSVPFVVLVLIFLTYFSLQVTHMGLFRPNSKIGQEVKKGAESQDVVKDVIKQRKAELGPMSCHEIQVGLLFVLMIFLLFTRKPGFFPGWADFLNAKA-----IGSGPPVFFATILLFALPTQYTFFKYCCGKA-PFPGQT-----------------LDACLSWVYCQKYTPFGLAFLLGGGFALAEGSRVSGMAKMLGESLAFAGEMHSVLVISMCIIISLFCTAFASNVAICNILIPIFSEMALAIE------------------------------------------------VHPMKLTFPAALACSLAFHLPVSTPPNAIISGFTGLKTKYMAIAGILPTCWAFLCLLFTGTVWTMLIYPGTTEFPSWAI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDQ0-1", "uniprot_id": "INDY2_DROME", "id": "Q9VDQ0-1", "name": "Protein I'm not dead yet 2", "aln": "MA-------------------EPGEQR--KFVLGRCCIFHWRGKASIIIPLITLPILIYGFQTDMAEFKCLWLIVTMALLWITETLPIYVTALFPLVFCPLLGLVNASIVCKQYFTDTIVVFLG-----GLIVALGIEYSNLHTRIALRVIRIVGGSPRRLFVGLMSVSTFMGLWISNSAGTAMMCPIVKALVNELDTNKIFPVYMTQEEEPVE--------------------------------------------------------------------------------EGEPPHPSKITVAFYAGIAYASSIGGLGTLIGTGTNLVFRGIYTERFPTST-------------VEITFANFMFYSIPLMVIVNVTLVIIAFLITHMGLFRPNSKTGKIIAEANTNRKLMEDVLRQRHIDLGPMSCHEIQMAIAFAFMIVLLITRKPGFVPGWSDLINRKV-----VGSASGLSFIVLLIFALPTQYTFFKYCCGKG-PFTAQA-----------------IDAILSWEYVLRNIPWGLLFLLGGGFALAVASRETGLNIMISKAMQVLIGLPNIVVQSITFVLANFFSAFNANVVVANIVLPILCEMSLALE------------------------------------------------LHPLILTLPACLGISMVYFLPVSTPPNAIVTQYAHIKTKYFACCGIVPTIIGISVALVNTNTWGLIIFPESKSFPDWAKEIKNQTKI---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VVT2-1", "uniprot_id": "INDY1_DROME", "id": "Q9VVT2-1", "name": "Protein I'm not dead yet", "aln": "MATETTKMIYTPPPLDIKMEIEIGEQPQPPVKCSNFFANHWKGLVVFLVPLLCLPVMLL---NEGAEFRCMYLLLVMAIFWVTEALPLYVTSMIPIVAFPIMGIMSSDQTCRLYFKDTLVMFMG-----GIMVALAVEYCNLHKRLALRVIQIVGCSPRRLHFGLIMVTMFLSMWISNAACTAMMCPIIQAVLEELQAQGVCKINHEPQYQIVGG--------------------------------------------------------------------------NKKNNEDEPPYPTKITLCYYLGIAYASSLGGCGTIIGTATNLTFKGIYEARFKNST-------------EQMDFPTFMFYSVP-SMLVYTLLTFVFLQWHFMGLWRPKSKEAQEVQRGREGADVAKKVIDQRYKDLGPMSIHEIQVMILFIFMVVMYFTRKPGIFLGWADLLNSKD-----IRNSMPTIFVVVMCFMLPANYAFLRYCTRRGGPVPTGP-----------------TPSLITWKFIQTKVPWGLVFLLGGGFALAEGSKQSGMAKLIGNALIGLKVLPNSVLLLVVILVAVFLTAFSSNVAIANIIIPVLAEMSLAIE------------------------------------------------IHPLYLILPAGLACSMAFHLPVSTPPNALVAGYANIRTKDMAIAGIGPTIITIITLFVFCQTWGLVVYPNLNSFPEWAQIYAAAALGNKTH-----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KTF1-1", "uniprot_id": "Q7KTF1_DROME", "id": "Q7KTF1-1", "name": "Protein I'm not dead yet", "aln": "----------------MAATQDYKPGDIPLEEQDDRRLFCKYHYKGVLLLFIPILLAPILIGTPVLICRFIYLTLCLYLIYILNLMARGAAAFIYMVFIPVAGIASSKEISVSYYTDLIFFVYS-----AIFMGIMMDSSKLSDRLAFIVISLVGGSLKFLQIFLTIAAAIVSILVNPTISAAFWMKVSQAVMVEYDNGGLIKLNSEEKPYEIG----------------------------------------------------------------------------------SKPYPTRPVIGIYLTCCYAASLAASLSPIVNPN-----GVISDGFGGSL-------------TVLEIG--MLMAGP--ALMGLVVMIFWLQVLFLGLLGGSVKRDLAEMAGAKA--GFKQTASERKQALGPWGIYPILALSLILLMFLLVATRKPRIFTGWDSINYKAES-----GLSVAGIGMSILFFAIPANYIFCRYYVCRQPEKEGPAN------------------SLLGWKAVNNNTPWAEIFMLGAAFSFSYSSAVCGLNTYLADSMNSDNKGFNMKSFICGALLGTLWTTLSPATTVAKLALPTMVTAGN-------------------------------------------------------SFSLPFATALHNQFLLPVSSPANTIVAGWGNVRPFQFLLGGSILTLFMFCTIAGFTILFRTMVL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P27514-1", "uniprot_id": "PHO91_YEAST", "id": "P27514-1", "name": "Low-affinity phosphate transporter PHO91", "aln": "---MKFSHSLQFNSVPEWSTKYLAYSQLKKLIYSLQKDKLYSNNKHHVVEPHDANDENLPLLADASPDDQFYISKFVAALNQELKKIDKFYISQETGLIANYNELKDDVMELENTNKATQLFNQQQQHQLQSVARNRKSKSQQRQRRFSSVSSTDSNPSLTDMSIDSAPVIHTQVSNTTNNGNSMQNLASASVSLSNSNPVYLSPFTQHRLSLKKRLISIYTQLSELKDFIELNQTG---FSKICKKFDKSLNTNLKQNYLNYIKFHSHVFNPATINRIQHHITETILTYASLNKGTRRPSNTFNLDADRINNDENSSGNEEDEDGNRQEVLDFQDAERELSSHLRDHVVWERNTVWKDMMNLERKYQSAKTDNKKFSKLSSSQLRPNANITESMAMSSGGAGIIAPSTDSLTFRELMHLPPKQWLQFIMGQTSLLKFLLITSCFIALLTFNLTP-FTQDSLQKNCFAILIYASLLWATETIPLFVTSLMIPLLIVVFPVIKDPITSQP----------------MSPRDSSQFILSTMWSSVIMLLLGGFTLAAALSKYNIAKVLSTHILASAGTNPHFILLTNMFVALFVSMWVSNVAAPVLCYSIVQPLLRTLPRNCSYAKALILGIALASNIGGMSSPIASPQNIFSIGIMDPSPSWAEWFMIALPVCFICVMAIWVLLIITFPPEPNVKILQLHPSRDPFTLKQWFVTLVCIITIVLWCLSNQISGIFGEMGIISIIPIVVFFGTGLLTSDDFNNFMWTIVVLAMGGTTLGKAVSSSGLLSTMAQLIKAQVEHEPIFIIVLIFGLVILVMATFVSHTVAAMIIVPLMSEIGSNLPSGDHSRLLIVIAALLCSSAMGLPTSGFPNVTAISMIDEVGDRYLTVGTFITRGVPASLLSYAAIVTVGYGILKVMGF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : . . .. :. . : : : . . : : . : : * : . . : . . . : : : : . * . ::: ..:::: . .: :. : : : . . : . . : :.. .* . : ", "identical_positions": 3, "similar_positions": 62, "identity": "0.33%" }, { "cls_id": "homologset.agr.SGD:S000005298", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D7B1-1", "uniprot_id": "DUS2_MOUSE", "id": "Q9D7B1-1", "name": "tRNA-dihydrouridine(20) synthase [NAD(P)+]-like", "aln": "------MIVNSLS------LCYHNKLILAPMVRVGTLPMRLLALDYGADIVYCEELIDLKMLQCKRVVNEVLSTVDFVAPDD------RVVFRTCER-EQSRVVFQMGTSDAERALAVARLVENDVAGIDVNMGCPKEYSTKGGMGAALLSDPDKIEKILSTLVKGTH----RPVTCKIRILPSLEDTLNLVKRIERTGISAIAVHGRNRDERPQHP---VSCEVIRAIAETLSIPVIANGGSHDHIQQHVDIEDFRQATAASSVMVARAAMWNPSIFLKDGLRP-----LEEVMQKYIRYAVQYDNHYTNTKYCLCQMLREQLESPQGRLLHAAQSSQEICEAFGLGAFYEETIRELDAR--RADLLAKTPEAVEEP----------AEDTSGIIKMAIRFDRRAYPP-QITPKMCLLEWCRREKLPQPVYETVQRTIDRMFCSVVTVAEQKYQSTLWDKSKKLAEQTAAIVCLRSQGLPEGRLGEESPSLNKRKREAPDQDPGGPRVQEPALPGEICKKPFVTLDSSEENLLEGC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NX74-1", "uniprot_id": "DUS2_HUMAN", "id": "Q9NX74-1", "name": "tRNA-dihydrouridine(20) synthase [NAD(P)+]-like", "aln": "------MILNSLS------LCYHNKLILAPMVRVGTLPMRLLALDYGADIVYCEELIDLKMIQCKRVVNEVLSTVDFVAPDD------RVVFRTCER-EQNRVVFQMGTSDAERALAVARLVENDVAGIDVNMGCPKQYSTKGGMGAALLSDPDKIEKILSTLVKGTR----RPVTCKIRILPSLEDTLSLVKRIERTGIAAIAVHGRKREERPQHP---VSCEVIKAIADTLSIPVIANGGSHDHIQQYSDIEDFRQATAASSVMVARAAMWNPSIFLKEGLRP-----LEEVMQKYIRYAVQYDNHYTNTKYCLCQMLREQLESPQGRLLHAAQSSREICEAFGLGAFYEETTQELDAQ--QARLSAKTSEQTGEP----------AEDTSGVIKMAVKFDRRAYPA-QITPKMCLLEWCRREKLAQPVYETVQRPLDRLFSSIVTVAEQKYQSTLWDKSKKLAEQAAAIVCLRSQGLPEGRLGEESPSLHKRKREAPDQDPGGPRAQELAQPGDLCKKPFVALGSGEESPLEGW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VY45-1", "uniprot_id": "Q9VY45_DROME", "id": "Q9VY45-1", "name": "", "aln": "MLRLPTILRKSFSMKTRQRLDYRNKLILAPMVRVGTLPMRLLALEMGADIVYTEELVDIKLIKSIRRPNPALGTVDFVDPSDG-----TIVFRTCAQ-ETSRLVLQMGTSDAGRALAVGKLLQRDISGLDINMGCPKEFSIKGGMGAALLADPDKAAHILRTLCSGLD----IPVTCKIRILPDVEGTIDLVQKLAATGIAAIGIHARTRDERPQHP---AHPEVLRAVAQAVDIPIIANGGSKN-MHCYDDLRKFQMECGADSVMVARAAQINVSIFRPEGLLP-----MDELIEKYLRLCVDYDNAPHNAKYCVQSILRELQETPRGKRFLQCQTLQQICEIWELGDYCRRKQRELKTMGNSGRAEVEPPEALAKRQKLEDAAIAITDEYDGIICRHMPFLRSTYPSDNHLPKTQLYVHAVKTGKSPPAYETQQ--CDKLFRSICTYDGQRFSSSFWEKNKKQAEQGAALVALLHLGQLEAEVLRDNGSLLN-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53720-1", "uniprot_id": "DUS2_YEAST", "id": "P53720-1", "name": "tRNA-dihydrouridine(20) synthase [NAD(P)+]", "aln": "------------------MVTYAGKLVLAPMVRAGELPTRLMALAHGADLVWSPEIIDKKLIQCVRKENTALQTVDYVVPSKVQTRPETLVFRTYPKLESSKLIFQIGSASPALATQAALKVINDVSGIDINAGCPKHFSIHSGMGSALLRTPDTLCLILKELVKNVGNPHSKPISVKIRLLDTKQDTLQLVKRLCATGITNLTVHCRKTEMRNREQPITDYIAEIYEICQANNVSLIVNGAIRD-RSHFHDLQANHWKNTNIGGMIAECAERDPTVFDHTSKPSEDGPSWVVACREFIQWATKFDNHIGNTKYMLSRIVPGKS-------------------------------------------------------------------------VFFQYFARCKSPEEVSFVLKQLNDDGSAQTDPSEYLENCRAQEKALKNANAIAKQKRKQTDHIGSDTKKQKVVPLPTDI-------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .**:******.* ** **:** ***:*: *::* *:::. * * .* ***:* *.. :**** : * .::::*:*::.. * .. : .*::*:*:* ****.:* :.***:*** **. ** * .. *:: ***:* :.*:.**::: ***: : :* *. : * :. : :.:: .:.:*.**. :: . *:. : . *:*..* : ::* . . .:::: ...:** *:** : :: . : .. : . * :: : . : *: ..: ... :: ..: ", "identical_positions": 88, "similar_positions": 124, "identity": "16.39%" }, { "cls_id": "homologset.agr.SGD:S000005299", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K1F2-1", "uniprot_id": "A0A0G2K1F2_RAT", "id": "A0A0G2K1F2-1", "name": "acetyl-CoA carboxylase", "aln": "MVLLLFLTCLVFSCLTISWLKIWGKMTDSKPLSNSKVDASLLSSKEESFSASDQSEEHG----DCSCPLTTPDQEELASHGGPVDASQQRNSVPSSHQKPPRNPLSSNDTCSSPELQTNRVAAPGSEVPEANGLPFPARPQTQRTGSPTREDKKQAHIKRQLMTSFILGSLDDNSSDEDPS----ASSFQTSSRKGSRA-SLGTLSQEAALNTADPESHTPTMRPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGNRVIETVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGPNNNNYANVELIIDIAKRIPVQAVWAGWGHASENPKLPELLCKHE--IAFLGPPSEAMWALGDKISSTIVAQTLQIPTLPWSGSGLTVEWTEDSQHQGKCISVPEDVYEQGCVRDVDEGLQAAEKVGFPLMIKASEGGGGKGIRRAESAEDFPMLFRQVQSEIPGSPIFLMKLAQNARHLEVQVLADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAAPAVFEFMEQCAVLLAKTVGYVSAGTVEYLYSQD-GSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPVSFETP-------LSPPIARGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLVNLLETESFQNNDIDTGWLDHLIAQRVQAEKPDIMLGVVCGALNVADAMFRTCMTEFLHSLERGQVLPADSLLNIVDVELIYGGIKYVLKVARQSLTMFVLIMNGCHIEIDAHRLNDGGLLLSYNGSSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLMQYTVEDGQHVEVGSSYAEMEVMKMIMTLNVQESGRVKYIKRPGAVLEAGCVVAKLELDDPSKVHAAQPFTGELPAQQTLPILGERLHQVFHSVLENLTNVMNGYCLPEPFFSMKLKDWVEKLMMTLRHPSLPLLELQEIMTSVAGRIPVPVEKAVRRVMAQYASNITSVLCQFPSQQCWASGMLGKHSTTELQPELLKIATILDCHAATLQRKVDREAFFMNTQSIVQLIQRYRSGTRGYMKAVVLDLLRRYLNVEHHFQQAHY--DKCVINLREQFKPDMTRVLDCIFSHSQVAKKNQLVTMLIDE---LCGPDPTLSEELTSILKELTQLSRSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPEN--------LKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRELPDGTCVVEFQFMLPSSHPN----------------------RMAMPINVSD--PDLLRHSKELFMDSGFSPLCQRMGAMVAFRRFEEFTRNFDEVISCFANVPTDTPLFSKACTSLYSEEDSKPS-----------------FFLSQSLQEEPIHILNVAIQCADHME-DERLVPVFRAFVQSKKHILVDYGLRRITFLIAQE---------------REFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRNFDLTAVPCANHKMHLYLGAAKVKEGLEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNN-TSVRTDCNHIFLNFVPTVIMDPLKIEESVRAMVMRYGSRLWKLRVLQAEVKINIRQTTSDCAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSFGNKQGSLHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWG--------SPEKYPKDILTYTELVLDSQGQLVEMNRLPGCNEVGMVVFKMRFKTPEYPEGRDTIVIGNDITFQIGSFGIGEDFLYLRASEMARTEGIPQIYLAANSGARMGLSEEIKQIFQVAWVDPEDPYKGFRYLYLTPQDYTQISSQ---NSVHCKHIEDEGESRYVIVDVIGKDSSLGVENLRGSGMIAGEASLAYEKNVTISMVTCRAIGIGAYLVRLGQRVIQVENSHIILTGAGALNKVLGREVYTSNNQLGGVQIMHTNGVSHVTVPDDFEGVCTILEWLSYIPKDNQSPVPIITPSDPIDREIEFTPT-KAPYDPRWLLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRSVEVAVPADPANLDSEAKIIQQAGQVWFPDSAFKTAQVIRDFNQ-EHLPLMIFANWRGFSGGMKDMYEQMLKFGAYIVDSLRLFKQPVLIYIPPGAELRGGAWVVLDSSINPLCIEMYADKESRGGVLEPEGTVEIKFRKKDLVKTIRRIDPVCKKLLGQLGTAQLPDK--DRKELESQLKAREDLLLPIYHQVAVQFADLHDTPGHMLEKGIISDVLEWKTTRTYFYWRLRRLLLEAQVKQEILRASPELSHEHTQSMLRRWFVETEGAVKAYLWDSNQVVVQWLEQHWSARDNLRSTIRENINYLKRDSVLKTIQSLVQEHPEATMDCVAYLSQHLTPAEQMQVVQLLSTTESPASH------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q4Z2-1", "uniprot_id": "ACACB_MOUSE", "id": "E9Q4Z2-1", "name": "Acetyl-CoA carboxylase 2", "aln": "MVLLLFLTCLVFSCLTFSWLKIWGKMTDSKPLTNSKVEANLLSS-EESLSASELSGEQ----------LQEHGDHSCLSYRGPRDASQQRNSLPSSCQRPPRNPLSSNDTWPSPELQTNWTAAPGPEVPDANGLSFPARPPSQRTVSPSREDRKQAHIKRQLMTSFILGSLDDNSSDEDPS----AGSFQNSSRKSSRA-SLGTLSQEAALNTSDPESHAPTMRPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGNRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGPNNNNYANVELIIDIAKRIPVQAVWAGWGHASENPKLPELLCKHE--IAFLGPPSEAMWALGDKIASTIVAQTLQIPTLPWSGSGLTVEWTEDSRHQGKCISVPEDVYEQGCVKDVDEGLQAAEKIGFPLMIKASEGGGGKGIRKAESAEDFPMLFRQVQSEIPGSPIFLMKLAQNARHLEVQVLADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAAPAVFEFMEQCAVLLAKMVGYVSAGTVEYLYSQD-GSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPIPFETP-------LSPPIARGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLVNLLETESFQNNDIDTGWLDHLIAQRVQAEKPDIMLGVVCGALNVADAMFRTCMTEFLHSLERGQVLPADSLLNIVDVELIYGGIKYALKVARQSLTMFVLIMNGCHIEIDAHRLNDGGLLLSYNGSSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLMQYTVEDGDHVEAGSSYAEMEVMKMIMTLNVQESGRVKYIKRPGVILEAGCVVARLELDDPSKVHAAQPFTGELPAQQTLPILGEKLHQVFHGVLENLTNVMSGYCLPEPFFSMKLKDWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKAVRRVMAQYASNITSVLCQFPSQ---------------------QIATILDCHAATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKAVVLDLLRKYLNVEHHFQQAHY--DKCVINLREQFKPDMTQVLDCIFSHSQVAKKNQLVTMLIDE---LCGPDPTLSDELTSILCELTQLSRSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPEN--------LKKLILSETTIFDVLPTFFYHENKVVCMASLEVYVRRGYIAYELNSLQHRELPDGTCVVEFQFMLPSSHPN----------------------RMAVPISVSN--PDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEEFTRNFDEVISCFANVQTDTLLFSKACTSLYSEEDSK------------------------SLREEPIHILNVAIQCADHME-DEALVPVFRAFVQSKKHILVDYGLRRITFLVAQE---------------REFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRNFDLTAVPCANHKMHLYLGAAKVKEGLEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNN-TSVRTDCNHIFLNFVPTVIMDPLKIEESVRDMVMRYGSRLWKLRVLQAEVKINIRQTTSDSAIPIRLFITNESGYYLDISLYREVTDSRSGNIMFHSFGNKQGSLHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWG--------SPEKYPKDILTYTELVLDSQGQLVEMNRLPGCNEVGMVAFKMRFKTPEYPEGRDAVVIGNDITFQIGSFGIGEDFLYLRASEMARTEGIPQIYLAANSGARMGLAEEIKQIFQVAWVDPEDPHKGFRYLYLTPQDYTQISSQ---NSVHCKHIEDEGESRYVIVDVIGKDANLGVENLRGSGMIAGEASLAYEKTVTISMVTCRALGIGAYLVRLGQRVIQVENSHIILTGAGALNKVLGREVYTSNNQLGGVQIMHTNGVSHVTVPDDFEGVCTILEWLSFIPKDNRSPVPITTPSDPIDREIEFTPT-KAPYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQVIRDFNK-ERLPLMIFANWRGFSGGMKDMYEQMLKFGAYIVDGLRLYEQPILIYIPPCAELRGGSWVVLDSTINPLCIEMYADKESRGGVLEPEGTVEIKFRKKDLVKTIRRIDPVCKKLVGQLGKAQLPDK--DRKELEGQLKAREELLLPIYHQVAVQFADLHDTPGHMLEKGIISDVLEWKTARTFFYWRLRRLLLEAQVKQEILRASPELNHEHTQSMLRRWFVETEGAVKAYLWDSNQVVVQWLEQHWSAKDGLRSTIRENINYLKRDSVLKTIQSLVQEHPEVIMDCVAYLSQHLTPAERIQVAQLLSTTESPASS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00763-1", "uniprot_id": "ACACB_HUMAN", "id": "O00763-1", "name": "Acetyl-CoA carboxylase 2", "aln": "MVLLLCLSCLIFSCLTFSWLKIWGKMTDSKPITKSKSEANLIPS-QEPFPASDNSGETPQRNGEGHTLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGTGTQGLEATDTNGLSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDSV----AGSSRESTRKGSRA-SLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKNG--VAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQD-GSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETP-------SNPPLARGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGALNVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIMNGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVARLELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIKLKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFPSQ---------------------QIATILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRVEHHFQQAHY--DKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDE---LCGPDPSLSDELISILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCPEN--------LKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVEFQFMLPSSHPN----------------------RMTVPISITN--PDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTRNFDEVISCFANVPKDTPLFSEARTSLYSEDDCK------------------------SLREEPIHILNVSIQCADHLE-DEALVPILRTFVQSKKNILVDYGLRRITFLIAQE---------------KEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELNRMRNFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNN-TSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGSRLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSFGNKQGPQHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWG--------SPDKYPKDILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIGSFGPGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFKYLYLTPQDYTRISSL---NSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSLAYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPS-RAPYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNR-EKLPLMIFANWRGFSGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYADKESRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDK--DRKDLEGRLKAREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVKQEILQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIRENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PKW2-1", "uniprot_id": "A0A8M9PKW2_DANRE", "id": "A0A8M9PKW2-1", "name": "acetyl-CoA carboxylase", "aln": "-------------------------MPSQTPISDCAG------------------------------------EHSPPMDPGLSSTSPRNEGIPPSATSDPTD-------------QSNITVS-----------HIESHRPRFGSGAQAKEKLK-----------FILGASEDNSSDDEPL----VKNQTTTHQPKNTE-TLNAEPTASSEMPPTPVPSTG-LRPSMSGPHLLKKGKEHRKMEVHRDFTVASPAEFVTRFGGNRIIDKVLIANNGIAAVKCMRSIRRWSYEMFRNERTIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVEMIVDIAKRIPVQAVWAGWGHASENPKLPELLHKSG--ICFLGPSSKAMWALGDKVASSIVAQSAGIPTLPWSGTGLSVEWAEEEQRQGRLISVPPELYVQGCVKDVDEGLASAEKIGYPVVIKASEGGGGKGIRKVESSEDFPSLFRQVQAEVPGSPIFIMQLAEHARHLEVQILADQYGNAISLFGRDCSIQRRHQKIIEEAPASIASTITFEQMEQYAVRLAKMVGYVSAGTVEYLFSED-GSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGIPLYRIKDIRVLFGEAPWGDTTINFESP-------ECMPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVGATGGLHEFADSQFGHCFSWGENREEAISNMVVAMKELSIRGDFRTTVEYLIKLLETESFRNNDIDTGWLDHLIADKVQAERPDTMLGVVCGALQVADASFRESMSDFLHSLERGQVLPAASLVNTVNVDLIYDGVKYCLKVARQSPTTYVIIMNDSDIEVDVHRLSDGGLLLSYGGSSYTTYMKEEIDRYRVTVGNKTCVFEKERDPTVLRSPSAGKLLQYVVTDGSHVSASQPYAEIEVMKMVMTLHVQHSGCIRFLKRPGTVLEPGCIVALMDLDDPSCIHQVKPNTEPLPAQEPLPMVGERLHQVFHNVLENLVKIMDGYCLPEPYFSQKLKNWVDTLMKTLRDPSLPLLELQEIMTSVAGRIPVTVEKAIRKVMAQYASNITSVLCQFPSQ---------------------RIANILDSHAATLQRKADREIFFMNTQSIVQLVQRYRSGIRGYMKSVVLDLLKHYLQVEMQFQQAHY--DKCVINLREQYKPDMTPVLECIFSHAQVSKKNILVTMLIDQ---LCGRDPMLADELMVILDELTQLSKMENSKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPEN--------LKKLILSETSIFDVLPSFFYHNNRVVCMAALEVYVRRAYIAYELNSLQHHQLQDGTCAVDFQFMLPSSHPNREPNATVSQHMPKSTGSSPTLNRLTLPVNDSGEFPAMRRQGSELFLEGALSPPCQRMGAMVAFHSFDHFKRCFDEVICRFVDPLCESSLFFDGCSTFCDGESCK------------------------NMKENPIHIINVSIKQADTED-DDALVTAFTAFAHSKKSLLYDYGIRRVTFLVAQK---------------REFPKYFTFRARDEFHEDRIYRNLEPALAFQLELNRMRNFDLKAVPCAHHRMQLYLGAARVEEGAEVTDYRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFSN-TPTRTDCNHIFLNFVPTVIMDPYKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTTTGDVIPIRLFLTNESGYYLDISLYKEVNDPSSGQIMFQSYGDKQGPLNGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWG--------PGDSYPKDVLMCNELVLDSQGNLVQMNRLPGDNEVGMVAFRMRMKTPEYPEGRDIIVICNDITHMIGSFGPQEDQLFMRASELARAEGIPRIYISANSGARIGLAEEIRHMFQVAWIDPEDPYKGFKYLYLTPQDYTRISSS---NSVHCHHVEEGGESRYILTDIIGKEEGIGVENLRGSGTIAGETSQAYKEIITISMVTCRAIGIGAYLVRLGQRVIQVENSHIILTGAGALNKVLGREVYTSNNQLGGVQIMHNNGVTHSTVPDDFEGVLTILQWLSYMPKSNQSPVPIKPATDPVDREIDFVPT-KAPYDPRWLLCGRPHPTVKGAWQSGFFDHGSFLEIMATWAQTVVVGRARLGGIPLGVIAVETRTVELAIPADPANLDSEAKLLQQAGQVWFPDSAYKTAQAIEDFNR-EKLPLMVFANWRGFSGGMKDMYDQVLKFGSYIVDALREFSQPVLVYIPPNAELRGGSWVVIDPTINLQHMELYADRESRGGVLEAEGTVEIKFRKKDLLKTMRRIDPVYSRLAEQLGKPDLPSQ--ERKDLEAKLKSREEFLLPIYHQVAVQFVDLHDTPGRMQEKGVITDILDWKTARSFFYWRLRRLLLEEVVKKEIMQANQDLSNGHIQSMLRRWFVETEGAVKAYLWDNNKVVVEWLENNLSQQDGTRSVIRENIKCIKRDYALKHIRSLVQANPEVTMDCIIHMAQNITPSQRAKVCHLLATMDNSTTS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5SWU9-1", "uniprot_id": "ACACA_MOUSE", "id": "Q5SWU9-1", "name": "Acetyl-CoA carboxylase 1", "aln": "----------------------------------------------------------------------------------MDEPSPLAKTLELN-----------------------------------------------------------------QHSRFIIGSVSEDNSEDEISNLVKLDLEE-KEGSLSPA-SVSSDTLSDLGISGLQDGLAFHMRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNG--IAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSK-RILNVPQDLYEKGYVKDVDDGLKAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQD-GSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLFRIKDIRMMYGVSPWGDAPIDFENS-------AHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQLNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQVLPAHTLLNTVDVELIYEGIKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAVESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPQIQSTALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPLNVEKSIKKEMAQYASNITSVLCQFPSQ---------------------QIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHY--DKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLVTMLIDQ---LCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIEN--------LQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNR--------------GNIPTLNRMSFASNLNHYGMTHVASVSDVLLDNAFTPPCQRMGGMVSFRTFEDFVRIFDEIMGCFCDSPPQSPTFPESGHTSLYDED-------------------------KVPRDEPIHILNVAIKTDGDIE-DDRLAAMFREFTQQNKATLVEHGIRRLTFLVAQKDFRKQVNCEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNN-TNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTTTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDILTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMSLKSPEYPDGRDIIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVDPEDPYKGYKYLYLTPQDYKRVSAL---NSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGSGMIAGESSLAYDEVITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHSTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPIDRIIEFVPT-KAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNR-EGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECSQPVMVYIPPQAELRGGSWVVIDPTINPRHMEMYADRESRGSVLEPEGTVEIKFRKKDLVKTMRRVDPVYIRLAERLGTPELSPT--ERKELESKLKEREEFLIPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLRRLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTEEDGVRSVIEENIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILSTMDSPST-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11497-1", "uniprot_id": "ACACA_RAT", "id": "P11497-1", "name": "Acetyl-CoA carboxylase 1", "aln": "----------------------------------------------------------------------------------MDEPSPLAKTLELN-----------------------------------------------------------------QHSRFIIGSVSEDNSEDEISNLVKLDLEE-KEGSLSPA-SVSSDTLSDLGISALQDGLAFHMRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGANNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNG--IAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSK-RILNVPQDLYEKGYVKDVDDGLKAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQD-GSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLFRIKDIRMMYGVSPWGDAPIDFENS-------AHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQLNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVNLRNSISNFLHSLERGQVLPAHTLLNTVDVELIYEGIKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAVESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPQIQSTALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSKVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPLNVEKSIKKEMAQYASNITSVLCQFPSQ---------------------QIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHY--DKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLVTMLIDQ---LCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYDVRHNQVESIFLSAIDMYGHQFCIEN--------LQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNR--------------GNIPTLNRMSFASNLNHYGMTHVASVSDVLLDNAFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSPPQSPTFPESGHTSLYDED-------------------------KVPRDEPIHILNVAIKTDGDIE-DDRLAAMFREFTQQNKATLVEHGIRRLTFLVAQKDFRKQVNCEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNN-TNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTTTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDILTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMSLKSPEYPDGRDVIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVDSEDPYKGYKYLYLTPQDYKRVSAL---NSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGSGMIAGESSLAYDEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHCTVCDDFEGVFTVLHWLSYMPKNVHSSVPLLNSKDPIDRIIEFVPT-KAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSVPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNR-EGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECSQPVMVYIPPQAELRGGSWVVIDPTINPRHMEMYADRESRGSVLEPEGTVEIKFRKKDLVKTMRRVDPVYIRLAERLGTPELSPT--ERKELESKLKEREEFLIPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLRRLLLEDLVKKKIHSANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTEEDGVRSVIEENIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILSTMDSPST-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13085-1", "uniprot_id": "ACACA_HUMAN", "id": "Q13085-1", "name": "Acetyl-CoA carboxylase 1", "aln": "----------------------------------------------------------------------------------MDEPSPLAQPLELN-----------------------------------------------------------------QHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPA-SVGSDTLSDLGISSLQDGLALHIRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNG--IAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSK-RILNVPQELYEKGYVKDVDDGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQD-GSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGVSPWGDSPIDFEDS-------AHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQMNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSVSNFLHSLERGQVLPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAVESGCIHYVKRPGAALDPGCVLAKMQLDNPSKVQQAELHTGSLPRIQSTALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSKVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQ---------------------QIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHY--DKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLVTMLIDQ---LCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIEN--------LQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNR--------------GNIPTLNRMSFSSNLNHYGMTHVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFSDSPPQSPTFPEAGHTSLYDED-------------------------KVPRDEPIHILNVAIKTDCDIE-DDRLAAMFREFTQQNKATLVDHGIRRLTFLVAQKDFRKQVNYEVDRRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNN-TNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDMLTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTFKSPEYPEGRDIIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVSANSGARIGLAEEIRHMFHVAWVDPEDPYKGYRYLYLTPQDYKRVSAL---NSVHCEHVEDEGESRYKITDIIGKEEGIGPENLRGSGMIAGESSLAYNEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHCTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPIDRIIEFVPT-KTPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNR-EGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECCQPVLVYIPPQAELRGGSWVVIDSSINPRHMEMYADRESRGSVLEPEGTVEIKFRRKDLVKTMRRVDPVYIHLAERLGTPELSTA--ERKELENKLKEREEFLIPIYHQVAVQFADLHDTPGRMQEKGVISDILDWKTSRTFFYWRLRRLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLAEWLEKQLTEEDGVHSVIEENIKCISRDYVLKQIRSLVQANPEVAMDSIIHMTQHISPTQRAEVIRILSTMDSPST-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YZ52-1", "uniprot_id": "A0A8M6YZ52_DANRE", "id": "A0A8M6YZ52-1", "name": "acetyl-CoA carboxylase", "aln": "----------------------------------------------------------------------------------MAEQDSTEKKLPAVAA---------------------------------------------------------------LHSHFIVGSVSEENSEDETAGKLDLQLED-NPRSLSPS-SVSSDSTYEMGFDSLDG-PLHNMRPSMSGLHLVKQGRDRRRIDLQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGTNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLHKNG--IAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGTGLTVEWTENDQKK-GIINVPTELYEQGCVHDVEAGLKAAEQVGFPVMVKASEGGGGKGIRKVNCAEDFPNLYRQVQAEVPGSPIFVMQLAKHARHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATSDVFEDMEKCAVKLAKMVGYVSAGTVEYLYSQD-SSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLHRIKDIRVLYGMQPWGDSPIDFDGL-------STTPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQHNSIDTGWLDRLISEKMQAERPDTMLGVVSGALHVADVNFRNSVSNFLHSLERGQVLPAHTLLNTVDVELIYEGTKYVLKVTRQSPNSYVVIMNCSSVEVDVHRLSDGGMLLSYDGSSYTTYMKEEVDRYRIIIGNKTCVFEKENDPSVLRSPSAGKLIQYTVEDGGHVFAGQCYAEIEVMKMVMTLTASESGCIHYVKRAGAVLEPGCIIGKLQLDDPSRVQQAELYTGTLPSIQSVALRGEKLHRVFHSTLGHLVHIMNGYCLPEPFFSAKLKEWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPAVEKAIKKEMAQYASNITSVLCQFPSQ---------------------QIANILDSHAATLNRKSEREVFFMNTQSIVQLVQKYRSGIRGHMKAVVMDLLRQYLRVEVQFQHGHY--DKCVFALREENKVDMANVLNYIFSHAQVTKKNCLVTMLIDQ---LCGRDPTLTDELMAILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIEN--------LQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCIVEFQFMLPTSHPNR--------------GNIPTLNRMSFSSNLNHYGMVHVASVSDVLLDTSFTPPCQRMGAMVSFRSFQEFTRNIKDVLSCFSDSPPSTPTFPEGGNPVLYREEDS-----------------------KSIQDEPIHILNVAIKTDSDID-DDGLAAMFREFTQSKKSLLFDHGIRRLTFLVAQKDFRKQINCEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFALTAIPCANHKMHLYLGAARVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLHNEAERLLLEAMDELEVAFNN-TTVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTPTGKQIPIRLFLTNESGYYLDISLYKEVTDSRTGQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYVYDFPEMFRQALRKLWQSMDAHANLPKCPLPSELLTFTELVLDSQGQLVQMNRLPGGNEIGMVAWRMTLRTPEYPAGREIIVISNDITHKIGSFGPQEDVLFQQASEMARESGIPRIYIAANSGARIGLAEEIRHMFHVAWQDPVDPYKGFKYLYLTPQDYKKVSAL---NSVHCEHVEDEGESRYKITDIIGKEEGLGVENLRGSGMIAGESSLAYEDIITMNLVTCRAIGIGAYLVRLGQRTIQVENSHIILTGAGALNKVLGREVYTSNNQLGGVQIMHNNGVTHTNVCDDFEGVYTLLHWLSYMPKNMSSPVPILSAKDPIDRAIEFVPT-KAPYDPRWMLAGRPNQNIKGAWVSGFFDQGSFLEIMQPWAQSVVVGRARLGGIPTGVVAVETRSVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTAQAIKDFNR-EGLPLIVFANWRGFSGGMKDMYDQVLKFGAYIVDGLREYRQPVLVYIPPQAELRGGSWVVIDPTINPRHMEMYADKDSRGGVLEPEGTVEIKFRKKDLVKTMRRVDPVYMGLAERLGTPELSVS--ERKELESKLKEREEFLLPIYHQVAVQFADLHDTPGRMQEKGVITDILEWSTSRQFFYWRLRRLLLEETVKRKIQCANSELTDGQVQAMLRRWFVEAEGAVKAYLWDSNEDVVEWLERQLAEEEGARSVIDENIKYIRRDHILKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILSTMDTPASS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z784-1", "uniprot_id": "A1Z784_DROME", "id": "A1Z784-1", "name": "", "aln": "-MLITILGTLAAFLAFLLTLIFGRGQKRSKPVQSSAATSATTATTGDSDNGNTNHNSSVIAATATATTTSSKPPIAPAAPPSAVKASDKRFPKACIKKVQFSSESLRSDVDELCDQLKDSALSNLSNDNIRIACHQNNNNSSINKNQNNNSIDISISISKMSETNESNDTAAQSAEGERPSFLVGDEIDERAAEAGEACDEFPLKMQNDVRQNGDISERRKRLRPSMSRGTGLGQDRHQ-----DRDFHIATTEEFVKRFGGTRVINKVLIANNGIAAVKCMRSIRRWAYEMFKNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGSNNNNYANVELIVDIALRTQVQAVWAGWGHASENPKLPELLHKEG--LVFLGPPERAMWALGDKVASSIVAQTAEIPTLPWSGSDLKAQYSG------KKIKISSELFARGCVTNVEQGLAAVNKIGFPVMIKASEGGGGKGIRRVDTTEEFPGLFRQVQAEVPGSPIFVMKLARGARHLEVQLLADQYGNAISLFGRDCSIQRRHQKIIEEAPAIVAQPEVFEDMEKAAVRLAKMVGYVSAGTVEYLYDPE-GRYFFLELNPRLQVEHPCTEMVADVNLPAAQLQIGMGIPLYRLKDIRLLYGESPWGSSVIDFENP-------PNKPRPSGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVAASGGLHEFADSQFGHCFSWGENRQQARENLVIALKELSIRGDFRTTVEYLITLLETNRFLDNSIDTAWLDALIAERVQSEKPDILLGVMCGSLHIADRQITESFSSFQTSLEKGQIQAANTLTNVVDVELINDGIRYKVQAAKSGANSYFLLMNSSFKEIEVHRLSDGGLLISLEGASYTTYMKEEVDRYRIVIGNQTCVFEKENDPSLLRSPSAGKLINMIVEDGAHVSKGQAYAEIEVMKMVMTLTSQEAGTVTFVRRPGAVLDAGSLLGHLELDDPSLVTKAQPFKGQFLQPENAPVP-EKLNRVHNTYKSILENTLAGYCLPEPFNAQRLRDIIEKFMQSLRDPSLPLLELQEVIASISGRIPISVEKKIRKLMTLYERNITSVLAQFPSQ---------------------QIASVIDSHAATLQKRADRDVFFLTTQSIVQLVQRYRNGIRGRMKAAVHELLRQYYDVESQFQYGHY--DKCVGLVREHNKDDMQTVVNTIFSHSQVAKKNLLVTLLIDH---LWANEPGLTDELANTLSELTSLNRAEHSRVALRSRQVLIAAHQPAYELRHNQMESIFLSAVDMYGHDFHPEN--------LQRLILSETSIFDILHDFFYHSNRAVCNAALEVYVRRAYTSYELTCLQHLELSGGLPLVHFQFLLPTAHPNR------------------LFSRMSSPDGLDQAAAESLGNS------------FVRTGAIAAFDSFEHFEMYSDEILDLLEDFVSPAMVNAKVLEAVEAADSISDSRHSTSINVSLSDPVTRANAAEEAKSTEPIHIVSVAVRETGELD-DLQMAQIFGNYCQEHNEELFQRRIRRITFAALKK---------------RQFPKFFTFRARDKFTEDRIYRHLEPASAFHLELNRMKTYDLEALPTANQKMHLYLGKAKVSKGQEVTDYRFFIRSIIRHSDLITKEASFEYLQNEGERVLLEAMDELEVAFSHPHAKRTDCNHIFLNFVPTVIMDPAKIEESVTKMIMRYGPRLWKLRVLQAELKMVIRQSPQSPTQAVRLCIANDSGYFLDISMYTEQTEPETGIIKFKAYGEKQGSLHGHPISTPYMTKDFLQQKRFQAQSNGTTYVYDVPDMFRQMTERHWREFSKARPTVDIRTPDKILIECKELVLEGDNLVEMQRLPGENNCGMVAWRIVLATPEYPNGREIIVIANDLTYLIGSFGIKEDVLFAKASQLARQLKVPRIYISVNSGARIGLAEEVKAMFKIAWEDPEEPDKGFKYLYLSTEDYAQVANL---NSVRAILIEDEGEQRYKITDIIGKDDGLGVENLRYAGLIAGETSQAYEEIVTIAMVTCRTIGIGSYVVRLGQRVIQIDNSHIILTGYAALNKLLGRKVYASNNQLGGTQIMFNNGVTHKTEAIDLDGVYTILDWLSYIPAYIGCDLPIVLPNDRIERPVDFMPT-KSPYDPRWMLGGRVNPVNANDWENGFFDRDSWSEIMASWAKTVVTGRARLGGVPVGVIAVETRTVEVEMPADPANLDSEAKTLQQAGQVWYPDSSYKTAQAIKDFGR-EELPLIVFANWRGFSGGMKDMYEQIVKFGAYIVDGLREYKKPVLIYLPPNAELRGGAWAVLDSLINPRYMETYADPEARGGVLEPEGIVEIKYKEKDLVKTIHRLDPTTIALKKELDEANASGDKVRAAQVDEKIKARIAVLMHVYHTVAVHFADLHDTPERMLEKECISEIVPWRDSRRWLYWRLRRLLLEDAYIKKILRAQDNLSVGQAKQMLRRWLVEEKGATEAYLWDKNEEMVSWYEEQIN----AESIVSRNVNSVRRDAIISTISKMLEDCPDVALDAVVGLCQGLTPVNRGVVVRTLAQMQLNEETSNSNQG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q00955-1", "uniprot_id": "ACAC_YEAST", "id": "Q00955-1", "name": "Acetyl-CoA carboxylase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEESLFESSPQKMEYEITNYSERHTELPGHFIGLNTVDK------------LEESPLRDFVKSHGGHTVISKILIANNGIAAVKEIRSVRKWAYETFGDDRTVQFVAMATPEDLEANAEYIRMADQYIEVPGGTNNNNYANVDLIVDIAERADVDAVWAGWGHASENPLLPEKLSQSKRKVIFIGPPGNAMRSLGDKISSTIVAQSAKVPCIPWSGTGVDTVHVDEKTG---LVSVDDDIYQKGCCTSPEDGLQKAKRIGFPVMIKASEGGGGKGIRQVEREEDFIALYHQAANEIPGSPIFIMKLAGRARHLEVQLLADQYGTNISLFGRDCSVQRRHQKIIEEAPVTIAKAETFHEMEKAAVRLGKLVGYVSAGTVEYLYSHDDGKFYFLELNPRLQVEHPTTEMVSGVNLPAAQLQIAMGIPMHRISDIRTLYGMNPHSASEIDFEFKTQDATKKQRRPIPKGHCTACRITSEDPNDGFKPSGGTLHELNFRSSSNVWGYFSVGNNGNIHSFSDSQFGHIFAFGENRQASRKHMVVALKELSIRGDFRTTVEYLIKLLETEDFEDNTITTGWLDDLITHKMTAEKPDPTLAVICGAATKAFLASEEARHKYIESLQKGQVLSKDLLQTMFPVDFIHEGKRYKFTVAKSGNDRYTLFINGSKCDIILRQLSDGGLLIAIGGKSHTIYWKEEVAATRLSVDSMTTLLEVENDPTQLRTPSPGKLVKFLVENGEHIIKGQPYAEIEVMKMQMPLVSQENGIVQLLKQPGSTIVAGDIMAIMTLDDPSKVKHALPFEGMLPDFGSPVIEGTKPAYKFKSLVSTLENILKGYDN-----QVIMNASLQQLIEVLRNPKLPYSEWKLHISALHSRLPAKLDEQMEELVARSLR----RGAVFPAR---------------------QLSKLIDMAVKNPEYNPDK-LLGAVVEPLADIAHKYSNGLEAHEHSIFVHFLEEYYEVEKLFNGPNVREENIILKLRDENPKDLDKVALTVLSHSKVSAKNNLILAILKHYQPLCKLSSKVSAIFSTPLQHIVELESKATAKVALQAREILIQGALPSVKERTEQIEHILKSSVVKVAYGSSNPKRSEPDLNILKDLIDSNYVVFDVLLQFLTHQDPVVTAAAAQVYIRRAYRAYTIGDIRVHEGVT-VPIVEWKFQLPSAAFS------------------------TFPTVKSKMGMNRAVSVSDLSYVANSQSSPLREGILMAVDHLDDVDEILSQSLEVIPRHQSSSNGPAPDRS---------------------------------GSSASLSNVANVCVASTEGFESEEEILVRLREILDLNKQELINASIRRITFMFGFKD--------------GSYPKYYTFNG-PNYNENETIRHIEPALAFQLELGRLSNFNIKPIFTDNRNIHVYEAVSKTSP----LDKRFFTRGIIRTGHIRDDISIQEYLTSEANRLMSDILDNLEVTDTS----NSDLNHIFINFIAVFDISPEDVEAAFGGFLERFGKRLLRLRVSSAEIRIIIKDPQTGAPVPLRALINNVSGYVIKTEMYTEVKN-AKGEWVFKSLG-KPGSMHLRPIATPYPVKEWLQPKRYKAHLMGTTYVYDFPELFRQASSSQWKNFS-----ADVKLTDDFFISNELIEDENGELTEVEREPGANAIGMVAFKITVKTPEYPRGRQFVVVANDITFKIGSFGPQEDEFFNKVTEYARKRGIPRIYLAANSGARIGMAEEIVPLFQVAWNDAANPDKGFQYLYLTSEGMETLKKFDKENSVLTERTVINGEERFVIKTIIGSEDGLGVECLRGSGLIAGATSRAYHDIFTITLVTCRSVGIGAYLVRLGQRAIQVEGQPIILTGAPAINKMLGREVYTSNLQLGGTQIMYNNGVSHLTAVDDLAGVEKIVEWMSYVPAKRNMPVPILETKDTWDRPVDFTPTNDETYDVRWMIEGR---ETESGFEYGLFDKGSFFETLSGWAKGVVVGRARLGGIPLGVIGVETRTVENLIPADPANPNSAETLIQEPGQVWHPNSAFKTAQAINDFNNGEQLPMMILANWRGFSGGQRDMFNEVLKYGSFIVDALVDYKQPIIIYIPPTGELRGGSWVVVDPTINADQMEMYADVNARAGVLEPQGMVGIKFRREKLLDTMNRLDDKYRELRSQLSNKSLAPE--VHQQISKQLADRERELLPIYGQISLQFADLHDRSSRMVAKGVISKELEWTEARRFFFWRLRRRLNEEYLIKRLSHQVGEASRLEKIARIRSWYP------ASVDHEDDRQVATWIEENYK-------TLDDKLKGLKLESFAQDLAKKIRSDHDNAIDGLSEVIKMLSTDDKEKLLKTLK--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : : : : :. :**. .** :*..:*********** :**:*:*:** * ::*:::**.*.*****:******:***:*: ****.********::*:*** * *:************* *** * : : *:**. .** :****::*::***: :* :****:.: . :.: ::: :* . : ** .:.:*:*:::************:.: ::* *::*. *:******:*:** :******:******. :********:*******:****. :* *. **: *: *.* ************:. : . :.************* ***::.**********.**:*:.*:.*** ::* * . : : *: * . ** *.*****:*::*****.**::******..********. *.:*.*:****** *::****: : .::*:*:****************:.****: * * * *.*** **:.:: :*:** *.*:.*: * . .: **::**: . * . . *::* * :* . .::.. : :::* . :: ::*.***:*:: * *:* * ***: *: :.. * ::* *.**: :*:**.*** : * :* *: .. ***:***** *.* . * : :::.* : .* ::. : **:** : . : : : .: * : : *: :. :: :: **.*.** * : :::: .*:* ::: :.. :: . **:: :::.::* . . : . :: : .:.:.:: ::* .* .. :: . .:*..* ** *: : :: : :*:. *: * ::**::*: ** *: ::.. * .. :: : * .:..*. .:***::*::** . *: . * :*:* *: *:: .: : *: ** *: :**:* *: * : .* *: :**:**.* :* : :: : *.::* **:: . : . * * : :. ::.. .: : : : . :: .*.: : : : : . :: * : :**:** : .:**::**.. :: *:. *::*** **:***.*: .: : .: ::.:::* . ::.. * *** *.*** ..: . : *** .*.:*:: : :*:***: . .:* ****:**:... :.* .:* :. :: *:* ** :*** .**::: *: . . .:* : * *** :. .:* * .: .. *:: * * *. : * *** .*: ** **::*: ****:**.*::*** * ....: : : . .:*..::* ** * ***.::: . : *** **: :*: **:*. ***** ** :: :.:: ** :*:**::.*****:*::**: :*::** *. :* **::****:.:. : *** **.*: : :**.: .:* * ** :* *** :* **.. .*: :****::***:*:******.**::.. :**** *:**:***:**:** **** ***. ***:* . *: ** .::.*:*::* :*: ..* :* ::* *: .** **:: ** . : *:** .*: * : **: **.*******:* **:.****:** :****** :* . :*:.****.*:*::** *.:.**.. * **::::********* :**:::::*:*::***.* :*:::*:** .*****:*.*:*. ** :* *** ::*..***.:* * **::.:.*:.::.*:* * .*. . . ::. :: * *: :* ::::*.*:** . :* * *.. : * :* :::***** * * :.: : . . :* * : :.:. :. * *.: : ::. : : . : :. : :* : : : ::. :: : : * ", "identical_positions": 751, "similar_positions": 714, "identity": "28.95%" }, { "cls_id": "homologset.agr.SGD:S000005300", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35093-1", "uniprot_id": "TIM23_RAT", "id": "O35093-1", "name": "Mitochondrial import inner membrane translocase subunit Tim23", "aln": "---MEGGGGSSNKSTGGLAGFFGAGGAGYSNADLAGVP------LTG-------MNPLSPYLNVDP--RYLVQDTDEFILPTGAN---KTRGRFELAFFTIGGCCMTGAAFGALNGLRLGLKETQSMPWSKPRNVQILNMVTRQGALWANTLGSLALLYSAFGVIIEKTRGAEDDFNTVAAGTMTGMLYKCTGGLRGIARGGLAGLTLTSVYALYNNWEHMKGSLLQQSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTQ8-1", "uniprot_id": "TIM23_MOUSE", "id": "Q9WTQ8-1", "name": "Mitochondrial import inner membrane translocase subunit Tim23", "aln": "---MEGGGRSSNKSTSGLAGFFGAGGAGYSNADLAGVP------LTG-------MNPLSPYLNVDP--RYLVQDTDEFILPTGAN---KTRGRFELAFFTIGGCCMTGAAFGAMNGLRLGLKETQSMAWSKPRNVQILNMVTRQGALWANTLGSLALLYSAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCTGGLRGIARGGLAGLTLTSLYALYNNWVHMKGSLLQQSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14925-1", "uniprot_id": "TIM23_HUMAN", "id": "O14925-1", "name": "Mitochondrial import inner membrane translocase subunit Tim23", "aln": "---MEGGGGSGNKTTGGLAGFFGAGGAGYSHADLAGVP------LTG-------MNPLSPYLNVDP--RYLVQDTDEFILPTGAN---KTRGRFELAFFTIGGCCMTGAAFGAMNGLRLGLKETQNMAWSKPRNVQILNMVTRQGALWANTLGSLALLYSAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCTGGLRGIARGGLTGLTLTSLYALYNNWEHMKGSLLQQSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SRD1-1", "uniprot_id": "TI23B_HUMAN", "id": "Q5SRD1-1", "name": "Mitochondrial import inner membrane translocase subunit Tim23B", "aln": "---MEGGGGSGDKTTGVLAGFFGAGEAGYSHADLAGVP------LTG-------MNPLCPYLNVDP--RYLVQDTDEFILPTGAN---KTWGRFELAFFTIGGCCMTGAAFGAMNGLRLGLKETQNMAWSKPGNVQILNMVTRQGALWANTLGSLALLYSAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCT----------VSEMALDSPFCVL-----LSGS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T2P6-1", "uniprot_id": "TIM23_DANRE", "id": "Q7T2P6-1", "name": "Mitochondrial import inner membrane translocase subunit Tim23", "aln": "---MDNSTPPPGGFKGGLGSIFGGGTPEYSNTELSGVP------LTG-------MSPLSPYLNVDP--RYLIQDTDEFILPTGAN---KTRGRFELAFFTIGGCCITGAAFGTLNGLRMGLSETRDMPWSKPRNVQILNMVTRQGASWANTLGSVALLYSVFGVAIEKARGAEDDLNTVAAGTLTGMVFKSTGGLKGVARGGLIGLAMSGLYALYNNWDHLKGKSPSHY-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32897-1", "uniprot_id": "TIM23_YEAST", "id": "P32897-1", "name": "Mitochondrial import inner membrane translocase subunit TIM23", "aln": "MSWLFGDKTPTDDANAAVGGQDTTKPKELSLKQSLGFEPNINNIISGPGGMHVDTARLHPLAGLDKGVEYLDLEEEQLSSLEGSQGLIPSRGWTDDLCYGTGAVYLLGLGIGGFSGMMQGLQNIPPNSPGKLQLNTVLNHITKRGPFLGNNAGILALSYNIINSTIDALRGKHDTAGSIGAGALTGALFKSSKGLKP------MGYSSAMVAAACAVWCSVKKRLLEK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. . . .. :.. * : *. ::* * * .:* .** : ::: *:: : * : : *. : * .:* :.*: **.: . .* :** :*::*. .*. * :** *. :. *: ** .* .::.**::** ::*.: : . :. ", "identical_positions": 35, "similar_positions": 64, "identity": "15.22%" }, { "cls_id": "homologset.agr.SGD:S000005302", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TQM4-1", "uniprot_id": "SOAT2_RAT", "id": "Q7TQM4-1", "name": "Sterol O-acyltransferase 2", "aln": "------------------------------MEPKAPQLR--RRERQGEEQENGACG-EGNTRTHR------APDLVQWTRHMEAVKTQCLEQAQRELAELMDRAIWEAVQAYPKQ--------------------DRP---------LPSTASDSTRKTQELHPGKRKVFITRKS-----------------------------LLDELMGVQHFRTIYHMFIAGLCVLIISTLAIDFIDEGRLMLEFDLLLFSFGQLPLALMMWVPMFLSTLLLP----------------------------YQTLRLWARPRSGGAWTLGASL--GCVLLAAHAAVLCVLPVHVSVKHELPPASR-CVLVFEQVRFLMKSYSFLRETVPGIFCVRGGK------GICT--PSFSSYLYFLFCPTLIYRETYPRTPSIRWNYVAKNFAQALGCLLYACFILGRLCVPVFANMSR-------EPFSTRALLLSILHATGPG-IFMLLLIFFAFLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLWLLGRQGRGAAMLGVFLVSALVHEYIFCFVLGFF--YPVMLILFLVVGGLLNFTMNDRHTGPAWNILMWTFLFLGQGIQVSLYCQEWYARRHCPLPQPTFWELVTPRSWSCHP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88908-1", "uniprot_id": "SOAT2_MOUSE", "id": "O88908-1", "name": "Sterol O-acyltransferase 2", "aln": "------------------------------MQPKVPQLR--RREGLGEEQEKGARGGEGNARTHG------TPDLVQWTRHMEAVKTQFLEQAQRELAELLDRALWEAMQAYPKQ--------------------DRP---------LPSAAPDSTSKTQELHPGKRKVFITRKS-----------------------------LIDELMEVQHFRTIYHMFIAGLCVLIISTLAIDFIDEGRLMLEFDLLLFSFGQLPLALMTWVPMFLSTLLVP----------------------------YQTLWLWARPRAGGAWMLGASL--GCVLLAAHAVVLCVLPVHVSVRHELPPASR-CVLVFEQVRLLMKSYSFLRETVPGIFCVRGGK------GISP--PSFSSYLYFLFCPTLIYRETYPRTPSIRWNYVAKNFAQVLGCLLYACFILGRLCVPVFANMSR-------EPFSTRALLLSILHATGPG-IFMLLLIFFAFLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLWLLGRRARGVAMLGVFLVSAVVHEYIFCFVLGFF--YPVMLMLFLVFGGLLNFTMNDRHTGPAWNILMWTFLFMGQGIQVSLYCQEWYARRHCPLPQTTFWGMVTPRSWSCHP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75908-1", "uniprot_id": "SOAT2_HUMAN", "id": "O75908-1", "name": "Sterol O-acyltransferase 2", "aln": "------------------------------MEPGGARLRLQRTEGLGGERERQPCG-DGNTETHR------APDLVQWTRHMEAVKAQLLEQAQGQLRELLDRAMREAIQSYPSQ--------------------DKP---------LPPPPPGSLSRTQEPSLGKQKVFIIRKS-----------------------------LLDELMEVQHFRTIYHMFIAGLCVFIISTLAIDFIDEGRLLLEFDLLIFSFGQLPLALVTWVPMFLSTLLAP----------------------------YQALRLWAR----GTWTQATGL--GCALLAAHAVVLCALPVHVAVEHQLPPASR-CVLVFEQVRFLMKSYSFLREAVPGTLRARRGE------GIQA--PSFSSYLYFLFCPTLIYRETYPRTPYVRWNYVAKNFAQALGCVLYACFILGRLCVPVFANMSR-------EPFSTRALVLSILHATLPG-IFMLLLIFFAFLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLRLLGARARGVAMLGVFLVSAVAHEYIFCFVLGFF--YPVMLILFLVIGGMLNFMMHDQRTGPAWNVLMWTMLFLGQGIQVSLYCQEWYARRHCPLPQATFWGLVTPRSWSCHT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61263-1", "uniprot_id": "SOAT1_MOUSE", "id": "Q61263-1", "name": "Sterol O-acyltransferase 1", "aln": "-----------------------------------MSLR--NRLSKSGENPEQDEAQKNFMDTYRN-GHITMKQLIAKKRLLAAEAEELKPLFMKEVGCHFDDFVTNLIEKSASL--------------------DNGGCALTTFSILEEMKKNHRAKDLRAPPEQGKIFISRQS-----------------------------LLDELFEVDHIRTIYHMFIALLILFVLSTIVVDYIDEGRLVLEFNLLAYAFGKFPTVIWTWWAMFLSTLSIP----------------------------YFLFQRWAHGYSKSSHPLIYSLVHGLLFLVFQLGVLGFVPTYVVLAYTLPPASR-FILILEQIRLIMKAHSFVRENIPRVLNAAKEK------SSKDPLPTVNQYLYFLFAPTLIYRDNYPRTPTVRWGYVAMQFLQVFGCLFYVYYIFERLCAPLFRNIKQ-------EPFSARVLVLCVFNSILPG-VLILFLSFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYVYKDLLWFFSKRFKSAAMLAVFALSAVVHEYALAICLSYF--YPVLFVLFMFFGMAFNFIVNDSRKRPIWNIMVWASLFLGYGLILCFYSQEWYARQHCPLKNPTFLDYVRPRTWTCRYVF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70536-1", "uniprot_id": "SOAT1_RAT", "id": "O70536-1", "name": "Sterol O-acyltransferase 1", "aln": "------------------------------MVGEETSLR--NRLSRSAENPEQDEAQKNLLDTHRN-GHITMKQLIAKKRQLAAEAEELKPLFLKEVGCHFDDFVTNLIDKSASL--------------------DNGGCALTTFSILEEMKNNHRAKDLRAPPEQGKIFISRRS-----------------------------LLDELFEVDHIRTIYHMFIALLIIFILSTLVVDYIDEGRLVLEFSLLAYAFGQFPIVIWTWWAMFLSTLAIP----------------------------YFLFQRWAHGYSKSSHPLIYSLIHGAFFLVFQLGILGFIPTYVVLAYTLPPASR-FILILEQIRLVMKAHSYVRENVPRVLSAAKEK------SSTVPVPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFLQVFGCLFYVYYIFERLCAPLFRNIKQ-------EPFSARVLVLCVFNSILPG-VLMLFLSFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYVYKDLLWFFSKRFRPAAMLAVFALSAVVHEYALAVCLSYF--YPVLFVLFMFFGMAFNFIVNDSRKRPVWNIMVRASLFLGHGVILCFYSQEWYARQRCPLKNPTFLDYVRPRTWTCRYVF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AC58HG58-1", "uniprot_id": "A0AC58HG58_DANRE", "id": "A0AC58HG58-1", "name": "", "aln": "-------------------------------------MI--DKDDFGPVTRNRRRATITSTRSES-------VKLRNG-ASAAAAAADSGLKSGHKARESLAKNLQLNEENKRKC--------------------DRY----------DRMSCHKLQESMLSSASSFKNYRGILN-----------------------------WCVVMLVLSNARLFLENLLRYGILVDPIQVVSLFLKDPYSWPAACLVIVCNAFILVALYTERKLAMGSISEK----------------------------VGLLIYIFNLTIILCFPMVVVLKLPSITPVGGAFALGIYTILFLKLYSYKDVNKWCRER-TQAKARSLSRSLSCPSPPSTSSSMQSY------VSYPGNLSLRDIYYFVFAPTLCYELNFPRSESIRMGFLLRRLFEMLLLTQLLVGLTQQWMVPIIRSSMKP-----LQEMDYTRMTERLLRLAVPN-HLLWLIFFYSFFHSSMNFMAELLRFGDREFYRDWWNSETITYFWQNWNIPVHKWCLRHFYKPLLRRGAG--KLLSQSAVFFASAFFHEDRMSSAV------CADWKGFLILKVSSSSVSGQCSSQDVQTVGIYGHDGTDSTGMVSVQVSSRQLWKCCCVALTHYRSTYRRSHVCS----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9ERM3-1", "uniprot_id": "DGAT1_RAT", "id": "Q9ERM3-1", "name": "Diacylglycerol O-acyltransferase 1", "aln": "-------------------------------------MG--DRGGAGSSRRRRTGSRVSVQGGSG-------PKVEEDEVREAAVSPDLGAGGDAPAPAPAPAHTRDKDRQTSVG--------------------DGH----------WELRCHRLQDSLFSSDSGFSNYRGILN-----------------------------WCVVMLILSNARLSLENLIKYGILVDPIQVVSLFLKDPYSWPAPCLIIASNIFIVATFQIEKRLSVGALTEQ----------------------------MGLLLHVVNLATIICFPAAVALLVESITPVGSLFALASYSIIFLKLSSYRDVNLWCRQRRVKAKAVSAGKKVSG-------AAAQNT------VSYPDNLTYRDLYYFIFAPTLCYELNFPRSPRIRKRFLLRRVLEMLFFTQLQVGLIQQWMVPTIQNSMKP-----FKDMDYSRIIERLLKLAVPN-HLIWLIFFYWLFHSCLNAVAELLQFGDREFYRDWWNAESVTYFWQNWNIPVHKWCIRHFYKPMLRLGSN--KWMARTGVFWASAFFHEYLVS----------IPLRMFRLWAFT--AMMAQVPLAWIVNRFFQGNYG---NAAVWVTLIIGQPVAVLMYVHDYYVLNYDAPVGA-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53629-1", "uniprot_id": "ARE2_YEAST", "id": "P53629-1", "name": "Sterol O-acyltransferase 2", "aln": "MDKKKDLLENEQFLRIQKLNAADAGKRQSITVDDEGELYGLDTSGNSPANEHTATTITQNHSVVASNGDVAFIPGTATEGNTEIVTEEVIETDDNMFKTHVKTLSSKEKARYRQGSSNFISYFDDMSFEHRPSILDGSVNEPFKTKFVGPTLEKEIRRREKELMAMRKNLHHRKSSPDAVDSVGKNDGAAPTTVPTAATSETVVTVETTIISSNFSGLYVAFWMAIAFGAVKALIDYYYQHNGSFKDSEILKFMTTNLFTVASVDLLMYLSTYFVVGIQYLCKWGVLKWGTTGWIFTSIYEFLFVIFYMYLTENILKLHWLSKIFLFLHSLVLLMKMHSFAFYNGYLWGIKEELQFSKSALAKYKDSINDPKVIGALEKSCEFCSFELSSQSLSDQTQKFPNNISAKSFFWFTMFPTLIYQIEYPRTKEIRWSYVLEKICAIFGTIFLMMIDAQILMYPVAMRALAVRNSEWTGILDRLLKWVGLLVDIVPGFIVMYILDFYLIWDAILNCVAELTRFGDRYFYGDWWNCVSWADFSRIWNIPVHKFLLRHVYHSSMSSFKLN-KSQATLMTFFLSSVVHELAMYVIFKKLRFYLFFFQMLQMPLVALTNTKFMRNRTIIGNVIFWLGICMGPSVMCTLYLTF-----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : * . . : .: : . : : .. :: : . : :.: . * : . . . : . :* : *** *. :**: :* :: .. : * :. :: *. .: :: *: : .. :* .**: :**** ** ****. : : : : **: **.: :.*: : : : .* *:. ** . : . . . . ", "identical_positions": 35, "similar_positions": 81, "identity": "5.21%" }, { "cls_id": "homologset.agr.SGD:S000005303", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R4I7-1", "uniprot_id": "M0R4I7_RAT", "id": "M0R4I7-1", "name": "Mitochondrial inner membrane protease ATP23", "aln": "MRETGGEGVRGRWLRCGRELHGQHWWATKHRPPRPAHHHAHPKARPELLVGASPRGPPVRLRAAEAATPRRPGRAGRRRLAGRMAGAPGGGEPGPEAGEPLLQRSDSGQGSSEPPAQGK--SQQGFLSSLFTRDQ-------SCPLMLLKTLETNPYVKLLLDAMKHS-GWCSGGGCSRLSVLSSAVNRGRHFSCEVCDGNVSGGFDASTSQIVLCENNIRNQAHMGRVVTHELIHAFDHCRAHVHWFTNVHHLACSEIRAASLSGDCSLVNELLR----LRFGLKQHHQTCVRDRAVLSILAVRN-ISREEAQKAVDEVFQACFNDREPFG-RIPHNKTYARYAHRDFQNRGRYYSNI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWQ3-1", "uniprot_id": "ATP23_MOUSE", "id": "Q9CWQ3-1", "name": "Mitochondrial inner membrane protease ATP23 homolog", "aln": "-----------------------------------------------------------------------------------MAGAPGGGELGPAAGEPLLQRPDSGQGSPEPPAHGK--PQQGFLSSLFTRDQ-------SCPLMLQKTLDTNPYVKLLLDAMKHS-------GC--------AVNRGRHFSCEVCDGNVSGGFDASTSQIVLCENNIRNQAHMGRVVTHELIHAFDHCRAHVHWFTNIRHLACSEIRAASLSGDCSLVNELFR----LRFGLKQHHQ-----------IETSC-VSR------------PAMNSQSCLG-LVSA----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6H3-1", "uniprot_id": "ATP23_HUMAN", "id": "Q9Y6H3-1", "name": "Mitochondrial inner membrane protease ATP23 homolog", "aln": "-----------------------------------------------------------------------------------MAGAPDERRRGPAAGEQLQQQHVSCQVFPERLAQGN--PQQGFFSSFFTSNQ-------KCQLRLLKTLETNPYVKLLLDAMKHS-------GC--------AVNKDRHFSCEDCNGNVSGGFDASTSQIVLCQNNIHNQAHMNRVVTHELIHAFDHCRAHVDWFTNIRHLACSEVRAANLSGDCSLVNEIFR----LHFGLKQHHQTCVRDRATLSILAVRN-ISKEVAKKAVDEVFESCFNDHEPFG-RIPHNKTYARYAHRDFENRDRYYSNI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4IGF3-1", "uniprot_id": "ATP23_DANRE", "id": "A4IGF3-1", "name": "Mitochondrial inner membrane protease ATP23 homolog", "aln": "-----------------------------------------------------------------------------MAQSGAKAADLSREPPGEQKPSPSSRQNEEDLGYNLYPERGSRLKKSTVEESLFTFKH-------KCQLMLQFAMDTSPYAKLLLGAMKSS-------GC--------TVFKDRHFSCEDCDGTVSGGFDAATSQIVLCQNNIHQQAHMNRVVTHELIHAFDHCRAQVDWFSNYRHLACSEIRAANLSGDCSFINEFSR----FNFGLRKHHQECVRGRALRSILAVRR-VSREEAERVVDEVFDSCFNDHAPFG-RIPHSKKDAKFAHRDFENRDRYYANL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJD0-1", "uniprot_id": "Q9VJD0_DROME", "id": "Q9VJD0-1", "name": "Mitochondrial inner membrane protease ATP23", "aln": "-------------------------------------------------------MEFLTKVWAKEATAPEAIEAITGAAQEKQNAKTEKASASKETSTEETTTAQKDWGYDLYPERRGETFKPKWTRVLFGLEGQENIDRFKCEENVYWCVKNGPLVKLMMGALKSSG-----C----------PIDLRRHISCEVCDPTVTGGYDPKLNQIVVCQNMARNKSMVHGVLTHEMIHMFDYCNNDMDFR-NVDHLACTEIRAANLA-HCSFLSAMFQG-DASPFNVKEAHQNCVKSKALASVLAVRN-ISKADAVAAVERVFPKCYADLEPIGRRIRRNSTDQQKAYMEAPMYGYDVY--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53722-1", "uniprot_id": "ATP23_YEAST", "id": "P53722-1", "name": "Mitochondrial inner membrane protease ATP23", "aln": "----------------------------------------------------------------------------------------MNSSGDNAGFEWWRRTMQYKTGIGLTPEEKTRYEDDSKARELKKECL-------KCYEYRDWMLKYSPTVRFMVQAITKLN-----KGSD-------SKFDDSKIICDYCPDWKGGGFHPELG-ILLCQNRLRDKWHLEDTLSHELIHYFDDLKWQIDWL-NLKHHACSEIRASSLSGECRFWEEFKRRGFRTGFHVARGHQDCVRRRAIISVSGNPNCQSKEHAAKIVDEVWDSCFADTRPFDEIYR-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : .* :. .* .:::: *:. . :: *: * **:.. . *::*:* ::: : .::**:** ** . .:.: * * **:*:**:.*: .* : . : : * : . ** *: . . :. ", "identical_positions": 29, "similar_positions": 56, "identity": "8.08%" }, { "cls_id": "homologset.agr.SGD:S000005304", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2X6-1", "uniprot_id": "CCD47_RAT", "id": "Q5U2X6-1", "name": "PAT complex subunit CCDC47", "aln": "-MKAFCAFCVVLLVFGSVSEAK---FDDFE--DEEDIVEYDD-NDFAEFEDVVEDSVT----ESPQR----VINTEDDEDEATVELE-GQDEGQEGDFEDADTQEGDTESEPYDDEEFEGYED---KPDTSSNKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNSHRELLESNFTLVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVQIKVTMNDEDMDTYVFAVGTRKALLRLQKEMQDLSEFCSDKPKSGAKYGLPDSLAILSEMGEVTEGMMDT-KMVHFLTHYADKIESVHFSDQFSGPKIMQEEGQPLKLPDTKRTLLFTFNVPGSGNTYPKDMEALLPLMNMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVKAM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D024-1", "uniprot_id": "CCD47_MOUSE", "id": "Q9D024-1", "name": "PAT complex subunit CCDC47", "aln": "-MKAFYAFCVVLLVFGSVSEAK---FDDFE--DEEDIVEYDD-NDFAEFEDVMEDSVT----ESPQR----VISTEDDEDEATVELE-GQDESQEGDFEDADTQEGDTESEPYDDEEFEGYED---KPDTSSNKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNSHRELLESNFTLVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVQIKVTMNDEDMDTYVFAVGTRKALLRLQKEMQDLSEFCSDKPKSGAKYGLPDSLAILSEMGEVTEGMMDT-KMVHFLTHYADKIESVHFSDQFSGPKIMQEEGQPLKLPDTKRTLLFTFNVPGSGNTYPKDMESLLPLMNMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVKAM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96A33-1", "uniprot_id": "CCD47_HUMAN", "id": "Q96A33-1", "name": "PAT complex subunit CCDC47", "aln": "-MKAFHTFCVVLLVFGSVSEAK---FDDFE--DEEDIVEYDD-NDFAEFEDVMEDSVT----ESPQR----VIITEDDEDETTVELE-GQDENQEGDFEDADTQEGDTESEPYDDEEFEGYED---KPDTSSSKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFTLVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVQIKVTMNDEDMDTYVFAVGTRKALVRLQKEMQDLSEFCSDKPKSGAKYGLPDSLAILSEMGEVTDGMMDT-KMVHFLTHYADKIESVHFSDQFSGPKIMQEEGQPLKLPDTKRTLLFTFNVPGSGNTYPKDMEALLPLMNMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVKAM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66I12-1", "uniprot_id": "CCD47_DANRE", "id": "Q66I12-1", "name": "PAT complex subunit CCDC47", "aln": "MRHLVFLLLPALLLLLALPDTRGRYNDDFD--DGEDIAEFDD-NDFAEFEDVSEDPAVDVEKEPPPRPAPSSTPVEDDEDEATVENEDGQDE-----FEDTDAQDQDMYN-KYDTDEFEGYE-------KSNPSFKDTLIYREVPAHLQNSWESYYMEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNSHRELLESNFALVGDDGTSKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLKFLKRQDLLNVLARMMRPTCDQVQVRVTLNDEDMDTFVFAVGSRKAMARMQKEMQDLSEFCGDKPKSGAKYGIPDSLTILSEMGEVTDGVMDN-KMVHYLTSHADKIESIHFSDQFSGPKVMQEEGQPLKLPETKKTLLFTFNVPGMGNTSPKDMDSLLPLMNMVIYSIDKVKKLRLNREGKQKADRNRARVEENFLKQTHAQRQEAAQTRREEKKRAEKERIMNEEDPERQRRLEEAAQRREQKKMEKKQMKMKQIKVKAM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQR9-1", "uniprot_id": "Q9VQR9_DROME", "id": "Q9VQR9-1", "name": "PAT complex subunit CCDC47", "aln": "-MRPVFAFLLLALICFASTKSE----SDFEEDDSDDFAEFDDGNFYAEPAAKNADSFS-----GGAG----SSHGESRDDPPAKEPR-KQAQNQESDEEDGLVEDDDEFEHFQDEEEFEGYDGGDSKDPPIDQKVEPKLNIPNIPLHFRTHWDSYWMEMLMVAGLLAYFANFFAGKAKNARLAQLWFSTHRALLDENFALVGDDGKAENENPG--LIKESESLYTLWCSGRTCCEGMLVELKMIKRQDLVSLVAGLMRPQLDQAHIKIELTRGVMDAFVFAVGTKKTITKLFKEYTDLSKFCSLVGKPEDRYNVPTGFGVLSEIPEATSAILES-RIITALNKYQSYIDYLHISDQFSGP-IQQEEGGTLKQPETKAVLLAGFNLP-----KHAEMETIKPLLLLIFYLMERLKTYRMSKEGKAKSDKNRQRVEEEFLKSTHAARAEAAAQRREDKRKQEKERILADEDPEKQRRWEAKEQKRQAKRNAP---KMKRLAVKSL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53723-1", "uniprot_id": "YN8B_YEAST", "id": "P53723-1", "name": "UPF0674 endoplasmic reticulum membrane protein YNR021W", "aln": "MSSSIFGPLTGFLERVNSLNAP---YQALSYDEQKAMTIWQRVKFYNWTFELCALGVL--------------------------------------FLVYAFYKFGNSVNLKRGNQIFQSLHS----------FLANDLKFSRVGFNIND------SKIFTVEHQNTWFSSFATGR---SAIKSINLNLHLVARSNPFSMC------------------LEYLLGFFFASLKSKQ-LEEFMEIVIRPNGILVTSESAHPNKNAHEILTKFR------FVTSIVNKEFMNQARTEN-----YFLSIAHTSENDKLPNNFVYMSDVNQLSGFMFHYSKPYEVLSQAGNLLKYISFTDLPVNPPRDDKEWESSIEPKAIIRCAVPQNENELKLLNQIISLVVEIYDGFTQDLVQQSPNLFITNDILKRTTNLRQQELNKIKKFMKETELELAKEKKLELEKAKRRQLKASGQQEKVDQKMKEKRERRLKNKQRTRFQ---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * .: . :. : . :. :: : : : : . . : *:. . : : ::. ::: * ::: .: *: : : . :. * .. *:: * : :: :. . : : :.:: * : : : : :* : .: : :* :: .:: : : .* : :. . :* .: :*:: : : ::. : *. . :. : ::* .* ::* . *.: * : : ::: . :..: :: . * : ::: * : . * * :: : .: ::.:: . : *: : .*. *. : ", "identical_positions": 26, "similar_positions": 141, "identity": "5.17%" }, { "cls_id": "homologset.agr.SGD:S000005306", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54772-1", "uniprot_id": "SMRD2_RAT", "id": "O54772-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "aln": "MSGRGAGGFPLPPLSPGGGAVAAALGAPPPPAGPGMLPNPALRGPGPSGGMGVPGAAAFRPMGPAG------------------------------------------------------------------PAAQYQRPGMSPGSRMPMAGLQVGPPAGSPFGTAAPLR-----PGMPPTMMDPFRKRLLVPQA---------QPPMPAQRR--------------------------------------------------GLKRRKMADKVLPQRIRELVPESQAYMDLLAFERKLDQTIARKRMEIQEAIKKPLTQKRKLRIYISNTFSPSKADGDNSGTAGTPGGTPAADKVASWELRVEGKLLDD------------PSKQKRKFSSFFKSLVIELDKELYGPDNHLVE-------------WHRMPTTQETDGFQVKRPGDLNVKCTLLLMLDHQP--PQYKLDPRLARLLGVHTQTRAAIMQALWLYIKHNQLQDGHEREYIN---------CNRYFRQIFSCGR---------------------------LRFSEIPMKLAG-LLQHPDPIVINHVISVDPNDQKKTACYDIDVEVDDPLKAQMSNFLASTTNQQEIASLDVKIHETIESINQLKTQRDFMLSFSTEPQDFIQEWLRSQRRDLKIITDVIGNPEEERRAAFYHQPWAQEAVGRHIFAKVQQRRQELEQVLGIRLT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JR8-1", "uniprot_id": "SMRD2_MOUSE", "id": "Q99JR8-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "aln": "MSGRGAGGFPLPPLSPGGGAVAAALGAPPPPAGPGMLPSPALRGPGPSGGMGVPGAAAFRPMGPAG------------------------------------------------------------------PAAQYQRPGMSPGSRMPMAGLQVGPPAGSPFGTAAPLR-----PGMPPTMMDPFRKRLLVPQA---------QPPMPAQRR--------------------------------------------------GLKRRKMADKVLPQRIRELVPESQAYMDLLAFERKLDQTIARKRMEIQEAIKKPLTQKRKLRIYISNTFSPSKADGDNAGTAGTPGGTPAADKVASWELRVEGKLLDD------------PSKQKRKFSSFFKSLVIELDKELYGPDNHLVE-------------WHRMPTTQETDGFQVKRPGDLNVKCTLLLMLDHQP--PQYKLDPRLARLLGVHTQTRAAIMQALWLYIKHNQLQDGHEREYIN---------CNRYFRQIFSCGR---------------------------LRFSEIPMKLAG-LLQHPDPIVINHVISVDPNDQKKTACYDIDVEVDDPLKAQMSNFLASTTNQQEIASLDVKIHETIESINQLKTQRDFMLSFSTEPQDFIQEWLRSQRRDLKIITDVIGNPEEERRAAFYHQPWAQEAVGRHIFAKVQQRRQELEQVLGIRLT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92925-1", "uniprot_id": "SMRD2_HUMAN", "id": "Q92925-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "aln": "MSGRGAGGFPLPPLSPGGGAVAAALGAPPPPAGPGMLPGPALRGPGPAGGVGGPGAAAFRPMGPAG------------------------------------------------------------------PAAQYQRPGMSPGNRMPMAGLQVGPPAGSPFGAAAPLR-----PGMPPTMMDPFRKRLLVPQA---------QPPMPAQRR--------------------------------------------------GLKRRKMADKVLPQRIRELVPESQAYMDLLAFERKLDQTIARKRMEIQEAIKKPLTQKRKLRIYISNTFSPSKAEGDSAGTAGTPGGTPAGDKVASWELRVEGKLLDD------------PSKQKRKFSSFFKSLVIELDKELYGPDNHLVE-------------WHRMPTTQETDGFQVKRPGDLNVKCTLLLMLDHQP--PQYKLDPRLARLLGVHTQTRAAIMQALWLYIKHNQLQDGHEREYIN---------CNRYFRQIFSCGR---------------------------LRFSEIPMKLAG-LLQHPDPIVINHVISVDPNDQKKTACYDIDVEVDDPLKAQMSNFLASTTNQQEIASLDVKIHETIESINQLKTQRDFMLSFSTDPQDFIQEWLRSQRRDLKIITDVIGNPEEERRAAFYHQPWAQEAVGRHIFAKVQQRRQELEQVLGIRLT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P9Z1-1", "uniprot_id": "SMRD3_MOUSE", "id": "Q6P9Z1-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "aln": "----------MAADEVAGGARKATKSKLFEFLVHG------------------------------------------------------------------------------------------------------VRPGMPSGARMPHQGAPMG-PPGSPYMGSPAVR-----PGLAPAGMEPARKRAAPPPG---------QSQAQGQGQPVP--------------TAPARSR--------------------------SAKRRKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNPAKPDAEDS--DGS---------IASWELRVEGKLLDD------------PSKQKRKFSSFFKSLVIELDKDLYGPDNHLVE-------------WHRTPTTQETDGFQVKRPGDLSVRCTLLLMLDYQP--PQFKLDPRLARLLGLHTQSRSAIVQALWQYVKTNRLQDSHDKEYIN---------GDKYFQQIFDCPR---------------------------LKFSEIPQRLTA-LLLPPDPIVINHVISVDPSDQKKTACYDIDVEVEEPLKGQMSSFLLSTANQQEISALDSKIHETIESINQLKIQRDFMLSFSRDPKGYVQDLLRSQSRDLKVMTDVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQRRQELEQSLVVRNT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZQQ2-1", "uniprot_id": "A0A8I5ZQQ2_RAT", "id": "A0A8I5ZQQ2-1", "name": "", "aln": "----------MAADEVAGGARKATKSKLFEFLVHG------------------------------------------------------------------------------------------------------VRPGMPSGARMPHQGAPMG-PPGSPYMGSPAVR-----PGLAPAGMEPARKRAAPPPG---------QSQAQGQGQPVP--------------TAPARSR--------------------------SAKRRKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNPAKPDAEDS--DGS---------IASWELRVEGKLLDDVRPGPGLSRCPGPSKQKRKFSSFFKSLVIELDKDLYGPDNHLVE-------------WHRTPTTQETDGFQVKRPGDLSVRCTLLLMLDYQP--PQFKLDPRLARLLGLHTQSRSAIVQALWQYVKTNRLQDSHDKEYIN---------GDKYFQQIFDCPR---------------------------LKFSEIPQRLTG-LLLPPDPIVINHVISVDPSDQKKTACYDIDVEVEEPLKGQMSSFLLSTANQQEISALDSKIHETIESINQLKIQRDFMLSFSRDPKGYVQDLLRSQSRDLKVMTDVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQRRQELEQSLVVRNT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6STE5-1", "uniprot_id": "SMRD3_HUMAN", "id": "Q6STE5-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "aln": "----------MAADEVAGGARKATKSKLFEFLVHG------------------------------------------------------------------------------------------------------VRPGMPSGARMPHQGAPMG-PPGSPYMGSPAVR-----PGLAPAGMEPARKRAAPPPG---------QSQAQSQGQPVP--------------TAPARSR--------------------------SAKRRKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNPAKPDAEDS--DGS---------IASWELRVEGKLLDD------------PSKQKRKFSSFFKSLVIELDKDLYGPDNHLVE-------------WHRTPTTQETDGFQVKRPGDLSVRCTLLLMLDYQP--PQFKLDPRLARLLGLHTQSRSAIVQALWQYVKTNRLQDSHDKEYIN---------GDKYFQQIFDCPR---------------------------LKFSEIPQRLTA-LLLPPDPIVINHVISVDPSDQKKTACYDIDVEVEEPLKGQMSSFLLSTANQQEISALDSKIHETIESINQLKIQRDFMLSFSRDPKGYVQDLLRSQSRDLKVMTDVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQRRQELEQSLVVRNT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BAQ8-1", "uniprot_id": "A0A8M2BAQ8_DANRE", "id": "A0A8M2BAQ8-1", "name": "", "aln": "----------MDMEDSAGGARKATKSKLFEFLVHG------------------------------------------------------------------------------------------------------VRPGMTSGARMPHQGAPMG-PPGPPYGGTPQIR-----PGMPNPALDPNRKRPAPTQP-VQPPSVQNRSRKKPLGFPAANEISARQMDMREAQSDPAIGS--------------------------NAKRRKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNPAKPDTEDS--EGS---------IASWELRVEGKLLDD------------PGKQKRKFSSFFKSLVIELDKDLYGPDNHLVEIALKHAAKIGETQWHRTPTTQETDGFQVKRPGDVNVRCTLLLMLDYQP--PQFKLDPRLARLLGIHTQTRSCIIQALWQYVKTNKLQDSHEKEYIN---------CDKYFQQIFDCPR---------------------------LKFCEIPQRLTN-LLLPPDPIVINHIISVDPNDQKKTACYDIDVEVDDPLKGQMNGFLLSTANQQEIASLDNKIHETIESINQLKIQRDFMLSFSRDPKGYIQDWICSQNRDLKLMTDTVGNPEEERRAEFYNQPWSQEAVSRYFYCKIQQRRQELEQALAMRTT--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q1P6-1", "uniprot_id": "A0A8M9Q1P6_DANRE", "id": "A0A8M9Q1P6-1", "name": "", "aln": "----------MASEETAGGARKATKSKLFEFLVHG------------------------------------------------------------------------------------------------------VRPGMPSGARMPHQGAPMG-PPGPPYGGSPAVR-----PGLTNQSMEASRKRPNPSQQQIQQQAVQNRNRKKPVGFPGPNEMPGRQMDLRETQSDPTLGSKFSDECWGKTSILRKKWSTQTERNSNSAKRRKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNAAKPDAEDS--EGS---------IASWELRVEGKLLDD------------PGKMKRKFSSFFKSLVIELDKDLYGPDNHLVE-------------WHRTGTTQETDGFQVKRPGDVNVRCTLLLMLDYQP--PQFKLDPRLARLLGIHTQTRSSIIQALWQYVKTNKLQDSHDKEYIN---------CDKYFQQIFDCPR---------------------------LKFSEIPQRLTN-LLLPPDPIVINHIISVDPNDQKKTACYDIDVEVEDPLKAQMSSFLLSTANQQEIASLDNKIHETIESINQLKIQRDFMLSFSRDPKGYIQDWLKSQSRDLKLMTDVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQRRQELEQALALRNT--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q96GM5-1", "uniprot_id": "SMRD1_HUMAN", "id": "Q96GM5-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "aln": "MAARAG----FQSVAPSGGAGASGGAGAAAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYP---------------------------------------------------------------------------RPGMLPGSRMTPQGPSMG-PPG--YGGNPSVR-----PGLAQSGMDQSRKRPAPQQI--------QQVQQQAVQNRNH-----------------------------------------------NAKKKKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRLDIQEALKRPIKQKRKLRIFISNTFNPAKSDAEDG--EGT---------VASWELRVEGRLLEDSALS-----KYDATKQKRKFSSFFKSLVIELDKDLYGPDNHLVE-------------WHRTATTQETDGFQVKRPGDVNVRCTVLLMLDYQP--PQFKLDPRLARLLGIHTQTRPVIIQALWQYIKTHKLQDPHEREFVI---------CDKYLQQIFESQR---------------------------MKFSEIPQRLHA-LLMPPEPIIINHVISVDPNDQKKTACYDIDVEVDDTLKTQMNSFLLSTASQQEIATLDNKIHETIETINQLKTQREFMLSFARDPQGFINDWLQSQCRDLKTMTDVVGNPEEERRAEFYFQPWAQEAVCRYFYSKVQQRRQELEQALGIRNT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZBS9-1", "uniprot_id": "D3ZBS9_RAT", "id": "D3ZBS9-1", "name": "", "aln": "MAARAG----FQSVAPSGGAGASGGAGVAAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYPVSGTGGGARGPGAGPSEGGGLTGVREKWEGLPREGLGPGVEVGETERRKSGGKEVSILTCSQRHCFRVRSECGTRRPGMLPGSRMTPQGPSMG-PPG--YGGNPSVR-----PGLAQSGMDQSRKRPAPQQI--------QQVQQQAVQNRNH-----------------------------------------------NAKKKKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRLDIQEALKRPIKQKRKLRIFISNTFNPAKSDAEDG--EGT---------VASWELRVEGRLLEDSALS-----KYDATKQKRKFSSFFKSLVIELDKDLYGPDNHLVE-------------WHRTATTQETDGFQVKRPGDVNVRCTVLLMLDYQP--PQFKLDPRLARLLGIHTQTRPVIIQALWQYIKTHKLQDPHEREFVI---------CDKYLQQIFESQR---------------------------MKFSEIPQRLHA-LLMPPEPIIINHVISVDPNDQKKTACYDIDVEVDDTLKTQMNSFLLSTASQQEIATLDNKIHETIETINQLKTQREFMLSFARDPQGFINDWLQSQCRDLKTMTDVVGNPEEERRAEFYFQPWAQEAVCRYFYSKVQQRRQELEQALGIRNT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61466-1", "uniprot_id": "SMRD1_MOUSE", "id": "Q61466-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "aln": "MAARAG----FQSVAPSGGAGASGGAGVAAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYP---------------------------------------------------------------------------RPGMLPGSRMTPQGPSMG-PPG--YGGNPSVR-----PGLAQSGMDQSRKRPAPQQI--------QQVQQQAVQNRNH-----------------------------------------------NAKKKKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRLDIQEALKRPIKQKRKLRIFISNTFNPAKSDAEDG--EGT---------VASWELRVEGRLLEDAALS-----KYDATKQKRKFSSFFKSLVIELDKDLYGPDNHLVE-------------WHRTATTQETDGFQVKRPGDVNVRCTVLLMLDYQP--PQFKLDPRLARLLGIHTQTRPVIIQALWQYIKTHKLQDPHEREFVL---------CDKYLQQIFESQR---------------------------MKFSEIPQRLHA-LLMPPEPIIINHVISVDPNDQKKTACYDIDVEVDDTLKTQMNSFLLSTASQQEIATLDNKIHETIETINQLKTQREFMLSFARDPQGFINDWLQSQCRDLKTMTDVVGNPEEERRAEFYFQPWAQEAVCRYFYSKVQQRRQELEQALGIRNT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VYG2-1", "uniprot_id": "BAP60_DROME", "id": "Q9VYG2-1", "name": "Brahma-associated protein of 60 kDa", "aln": "----------MSQRFAPGQAPVQSRYQPPP-PAPG------------------------------------------------------------------------------------------------------MRPYPPPGASFPPRGFPLHPNTTQPVPGTANVAGVPGVPGVPGVPGPSLLQRAAQQPG--------FQSSLRGTGAGGGGVGSGGGSKRSNESRSLGGGGSKSD-------------------FATAKKKKKLAEKILPQKVRDLVPESQAYMDLLTFERKLDATIMRKRLDIQEALKRPMKQKRKLRIFISNTFYPSKEPTNDG-EEGA---------VASWELRVEGRLLEDGKGD-------PNTKIKRKFSSFFKSLVIELDKELYGPDNHLVE-------------WHRTHTTQETDGFQVKRPGDRNVRCTILLLLDYQP--LQFKLDPRLARLLGVHTQTRPVIISALWQYIKTHKLQDAHEREYIN---------CDKYLEQIFSCQR---------------------------MKFAEIPQRLNP-LLHPPDPIVINHFIESG-AENKQTACYDIDVEVDDTLKNQMNSFLMSTASQQEIQGLDTKIHETVDTINQMKTNREFFLSFAKDPQMFIHRWIISETRDLKLMTDVAGNPEEERRAEFYYQPWTHEAVSRYFFTKVNQKRAELEQALGIRNG--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53628-1", "uniprot_id": "SNF12_YEAST", "id": "P53628-1", "name": "Transcription regulatory protein SNF12", "aln": "----------MSKVMKPSNGKGSRKSSKAATPDTKN----------------------------------------------------------------------------------------------------FFHAKKKDPVNQDKANNASQITPTVPHSHPSDMVIPDHLAELIPELYSFQQLVDSEKRLDHFIHLRNLHMKRMVAQWERSKLSQEFLYP------------------------------------HLNFPNVKFLRIFISNVSENQPWQMDTNNEADLMALENATWTMRIEGRLLDNVQANDPAREKFSSFIESIVVDFKNKENDNVPSTKFN-------AAPEENATEGPSDKKLNLN-------LPLQFSLPNGDNSTTTNTDQNNATMGEETAKKDMSSTTPKLESVKWQYDPNNPVDFDGLDIKRVGSENVECTISILRKSSPEEPFMSYSPQLTAIIGLKSGTSHDAIFSIYKYIHLNELLTNDESAFENLMGNRNNHNSNTSTSKMLDAASSQVSIVKLDTQLITLLPSSLKESSPDTMKLTDLLSLINSTHLLPLQPIEIDYTVRVDKASTYGELVLDIEVPDVNALKFNN-TQRESQIGAAELNENARELEQIKPKIALQDKEITSVLSNLHESNKRYRFFKKISEDPVKALNECIASTSNALKVLSGDEGYNEDMVRRANFYKENEAMLRENIEVILSNGRM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . :. . . . : . : : . *: .:.: .: : :: : : : * . : : :: :.*: :*.. . * :. *. * .** .. : . .. .: : :: * :. : : .. : **:::** *. .*.**: :: . .* . .*:*: ::*::: : : ::: *:: :.* .: : : :::.. ::: :: : * :** *:: : . . **:* :.** : * . *: ::.: .* . : .** :.: . . :* :.: ....: :. : : .: * * : * :: . : : : ", "identical_positions": 42, "similar_positions": 151, "identity": "5.78%" }, { "cls_id": "homologset.agr.SGD:S000005310", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K183-1", "uniprot_id": "PDXK_MOUSE", "id": "Q8K183-1", "name": "Pyridoxal kinase", "aln": "----MEGECR-VLSIQSHVVRGYVGNRAAMFPLQVLGFEVDAVNSVQFSNHTGYAHWKGQVLKSQELHELYEGLKVNDVN-KYDYVLTGYTRDKSFLAMVVDIVRELKQQNSRLVYVCDPVMGDKWNGEGSMYVPQDLLPVYRDKVVPVADIIT-PNQFEAELLSGRKIHSQEEAFEVMDMLHCMGPDTVVITSSDLPSSQGSDYLIALGSQRMRKPDGSTVTQRIRMEMRKVEAVFVGTGDLFAAML----LAWTHKHPDNLKVACEKTVSAMQHVLQRTIRCAKAEAGEGQKPSPAQLELRMVQSKRDIEDPEIVVQATVL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LEN0-1", "uniprot_id": "A0ABK0LEN0_RAT", "id": "A0ABK0LEN0-1", "name": "Pyridoxal kinase", "aln": "----MSSHYTDSWEMLGWGSWLPWTCRKDLEGRQVLGFEVDAVNSVQFSNHAGYAHWKGQVLTSQELHALYEGLKANNVN-KYDYVLTGYTRDKSFLTMVVDIVKELKQQNSKLMYVCDPVMGDKRNGEGSMYVPQDLLPVYREKVVPMADIIT-PNQFEAELLSGRKIHSQEEAFAVMDVLHRMGPDTVVITSSDLPSPKGSDYLMALGSQRMRKPDGSTVTQRIRMEMRKLDAVFVGTGDLFAAML----LAWTHKHPDNLKVACEKTVSAMQHVLQRTIRCAKAEAGEGQKPSPAQLELRMVQSRKDIEDPEIVVQATVL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00764-1", "uniprot_id": "PDXK_HUMAN", "id": "O00764-1", "name": "Pyridoxal kinase", "aln": "----MEEECR-VLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQELYEGLRLNNMN-KYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGSMYVPEDLLPVYKEKVVPLADIIT-PNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAML----LAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDIEDPEIVVQATVL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S7H1-1", "uniprot_id": "B0S7H1_DANRE", "id": "B0S7H1-1", "name": "Pyridoxal kinase", "aln": "------MDCR-VLSVQSHVVRGYVGNKSATFPLQVLGFEVDTINSVQFSNHTGYEHWKGQVLTADELNVLYEGIKLNDVN-HYDYVLTGYTRDYSFLDMVVDIVQELKRANPSLVYVCDPVLGDN----GAMYVPENLLPIYRDRVVPAADIIT-PNQFEAELLSGRKIHSEKDAVEVMNLLHSMGPDTVVITSSDLPSPLGDQYLVALGSQKKVRTDGSMVTQQIRMDIPRVDAVFVGTGDLFAAML----LAWTHHHP-DLKMACEKTASVLHHVIKRTMTYAHEVAGPNRRPSPAQLELRMVQSKADIENPAVVVNAVIL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B8A4Q2-1", "uniprot_id": "B8A4Q2_DANRE", "id": "B8A4Q2-1", "name": "Pyridoxal kinase", "aln": "------MECR-VLSIQSHVVRGYVGNKSASFPLQVMGFEVDSINSVQFSNHTGYAHWKGQVLTADELHVLYEGIKLNNVN-HYDYVLTGYNRDTSFLEMVADIVQELKRANPNLVYVCDPVLGDH----GSMYVPQNLHPVYKNKVVPVADIIT-PNQFEAELLTGKNISTEKDAVEVMDLLHKMGPDTVVITSSDLPPRLGDRFLVSLGSQRILMPDGTRTTQRIRIEVPKVDAVFVGTGDLFAAML----LAWTHHYPTDLKTACEKTFSVMHHVIQRTISYAHEMAGPGRRPSPSQLELRMVQSKADIEDPAIVMEATVL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KUC2-1", "uniprot_id": "Q7KUC2_DROME", "id": "Q7KUC2-1", "name": "Pyridoxal kinase", "aln": "MAGATNADIKRVLSIQSHVVHGYVGNKVATYPLQLLGFDVDPLNSVQFSNHTGYKTFKGPVSNEKELATIFEGLEENELLPLYSHLLTGYIGNPLFLRQVGHILKKLRQANPGLVYVCDPVMGDN----GQLYVPKELLPVYRDEIIPLADIIT-PNQFEVELLTEKEVRSEAAVWEAMEWFHQRGIKTVVISSSDLGQP---GVLRAFLSQQ----NGPRLAIDIPKQGGK-DLVFTGTGDLFASLF----LAHSHGSK-DIANVFEKTIASLQAVIKRTV--ASLPNGGNGPVKAAERELKLVQSKTEIEQPQVLLKAQRLN---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53727-1", "uniprot_id": "BUD17_YEAST", "id": "P53727-1", "name": "Putative pyridoxal kinase BUD17", "aln": "-MTSTLHTTKKVLSIQSHVIHGYVGNKAATFPLQYRGWDVDVLNTVQFSNHSGYAHFTGFKCSTEELVDIVEKGLIGSLRIKYDAVLSGYLPNVQALQKVAGIVGQLCEGSENVKWILDPVLGDN----GRLYVDRECVAVYQDILQNFKIFLATPNQFEMELLVGMSIRTLDDAKQAFKLFHKKYPRVSRIVVTSLELS----EFLSNDTYVVAGFDCSASEEIFFYEIPKINAKFSGSGDLISAMLTDSLLGDRRCTQLSLSASLGQVLWLVTSILQKTYDLNIAERGP-QDSTIDIKDLKLIQCRDILKQDLIPSIGKPKTIKI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . : * *:::* :*:******:** :.* . .** : * ..: *. :*:** : * * *: :* . . : :: ***:**: * :** .: .:*:: : ::: ***** *** .: : . .:. :* . * :.* : : . : : : : * *:***::::: *. : .: :. : ::::* * . :*:::*.: ::: : . ", "identical_positions": 54, "similar_positions": 89, "identity": "16.51%" }, { "cls_id": "homologset.agr.SGD:S000005312", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MB4-1", "uniprot_id": "ZNG1_RAT", "id": "Q99MB4-1", "name": "Zinc-regulated GTPase metalloprotein activator 1", "aln": "MLPAMKTVEAEEEYAED-CPELVPIETKHQEKEENLDF------------------------------IIKIPVTIVTGYLGAGKTTLLNYILTEQHNRKIAVILNEFGEGSAVEKSLAVSQGGELYEEWLELRNGCLCCSVKDNGLKAIENLMQKK-GKFDYILLETTGLADPGAVASMFWVDAELGSDIYLDGIITVVDSKYGLKHLTEE-----------KPDGLVNEATRQVALADMILINKTDLVSE--EELNKLRTTIRSINGLGKVLETQRSRTHLSNILDLHAYDTLSGISLQKKLQHVS-TAPHLDQSIVTVTFDVPGSAEEESLN-----VFIQNLLWEKN--------VKNKDGRCMEVIRLKGLVSIK-DKPQQMIVQGIHELYELEESRVNWKDDAERACQLVFIGKNLDKDILQQLFITAVAETKEQTTAPGQ-DGACPPH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEH6-1", "uniprot_id": "ZNG1_MOUSE", "id": "Q8VEH6-1", "name": "Zinc-regulated GTPase metalloprotein activator 1", "aln": "MLPAVKTVEAEEEYAED-CPELVPIETKNQE-EENLDF------------------------------ITKIPVTIVTGYLGAGKTTLLNYILTEQHNRKIAVILNEFGEGSAVEKSLAVSQGGELYEEWLELRNGCLCCSVKDSGLRAIENLMQKK-GKFDYILLETTGLADPGAVASMFWVDAELGSDIYLDGIITVVDSKYGLKHLTEE-----------KPDGLVNEATRQVALADMILINKTDLVSE--EELNNLRTTIRSINGLGKVLETQRSRVHLSNILDLHAYDILSGISLQKKLQHVS-TAPHLDQSIVTVTFEVPGSAKEECLN-----VFIQNLLWEKN--------VKNKDGHCMEVIRLKGLVSIK-DKPQQMIVQGIHELYDLEESLVNWKDDAERACQLVFIGRNLDKDVLQQLFLTAVAEAEEQRTAPGR-DGVCPSH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JTY5-1", "uniprot_id": "ZNG1C_HUMAN", "id": "Q5JTY5-1", "name": "Zinc-regulated GTPase metalloprotein activator 1C", "aln": "MLPAVGSVDEEEDPAEEDCPELVPIETTQSEEEEKSGL------------------------------GAKIPVTIITGYLGAGKTTLLNYILTEQHSKRVAVILNESGEGSALEKSLAVSQGGELYEEWLELRNGCLCCSVKDNGLRAIENLMQKK-GKFDDILLETTGLADPGAVASMFWVDAELGSDIYLDGIITIVDSKYGLKHLTEE-----------KPDGLINEATRQVALADIILINKTDLVPE--EDVKKLRTTIRSINGLGQILETQRSRVDLSNVLDLHAFDSLSGISLQKKLQHVPGTQPHLDQSIVTITFEVPGNAKEEHLN-----MFIQNLLWEKN--------VRNKDNHCMEVIRLKGLVSIK-DKSQQVIVQGVHELYDLEETPVSWKDDTERTNRLVLIGRNLDKDILKQLFIATVTETEKQWTTHFKEDQVCT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RIA9-1", "uniprot_id": "ZNG1E_HUMAN", "id": "Q5RIA9-1", "name": "Zinc-regulated GTPase metalloprotein activator 1E", "aln": "MLPAVGSVDEEEDPAEEDCPELVPIETTQSEEEEKSGL------------------------------GAKIPVTIITGYLGAGKTTLLNYILTEQHSKRVAVILNESGEGSALEKSLAVSQGGELYEEWLELRNGCLCCSVKDNGLRAIENLMQKK-GKFDDILLETTGLADPGAVTSMFWVDAELGSDIYLDGIITIVDSKYGLKHLTEE-----------KPDGLINEATRQVALADIILINKTDLVPE--EDVKKLRTTIRSINGLGQILETQRSRVDLSNVLDLHAFDSLSGISLQKKLQHVPGTQPHLDQSIVTITFEVPGNAKEEHLN-----MFIQNLLWEKN--------VRNKDNHCMEVIRLKGLVSIK-DKSQQVIVQGVHELYDLEETPVSWKDDTERTNRLVLIGRNLDKDILKQLFIATVTETEKQWTTHFKEDQVCT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4V339-1", "uniprot_id": "ZNG1F_HUMAN", "id": "Q4V339-1", "name": "Zinc-regulated GTPase metalloprotein activator 1F", "aln": "MLPAVGSVDEEEDPAEEDCPELVPIETTQSEEEEKSGL------------------------------GAKIPVTIITGYLGAGKTTLLNYILTEQHSKRVAVILNESGEGSALEKSLAVSQGGELYEEWLELRNGCLCCSVKDNGLRAIENLMQKK-GKFDDILLETTGLADPGAVASMFWVDAELGSDIYLDGIITIVDSKYGLKHLTEE-----------KPDGLINEATRQVALADIILINKTDLVPE--EDVKKLRTTLRSINGLGQILETQRSRVDLSNVLDLHAFDSLSGISLQKKLQHVPGTQPHLDQSIVTITFDVPGNAKEEHLN-----MFIQNLLWEKN--------VRNKDNHCMEVIRLKGLVSIK-DKSQQVIVQGVHELCDLEETPVSWKDDTERTNRLVLIGRNLDKDILKQLFIATVTETEKQWTTHFKEDQVCT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BRT8-1", "uniprot_id": "ZNG1A_HUMAN", "id": "Q9BRT8-1", "name": "Zinc-regulated GTPase metalloprotein activator 1A", "aln": "MLPAVGSADEEEDPAEEDCPELVPIETTQSEEEEKSGL------------------------------GAKIPVTIITGYLGAGKTTLLNYILTEQHSKRVAVILNEFGEGSALEKSLAVSQGGELYEEWLELRNGCLCCSVKDSGLRAIENLMQKK-GKFDYILLETTGLADPGAVASMFWVDAELGSDIYLDGIITIVDSKYGLKHLTEE-----------KPDGLINEATRQVALADAILINKTDLVPE--EDVKKLRTTIRSINGLGQILETQRSRVDLSNVLDLHAFDSLSGISLQKKLQHVPGTQPHLDQSIVTITFEVPGNAKEEHLN-----MFIQNLLWEKN--------VRNKDNHCMEVIRLKGLVSIK-DKSQQVIVQGVHELYDLEETPVSWKDDTERTNRLVLLGRNLDKDILKQLFIATVTETEKQWTTRFQEDQVCT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IUF1-1", "uniprot_id": "ZNG1B_HUMAN", "id": "Q8IUF1-1", "name": "Zinc-regulated GTPase metalloprotein activator 1B", "aln": "MLPAVGSADEEEDPAEEDCPELVPMETTQSEEEEKSGL------------------------------GAKIPVTIITGYLGAGKTTLLNYILTEQHSKRVAVILNEFGEGSALEKSLAVSQGGELYEEWLELRNGCLCCSVKDNGLRAIENLMQKK-GKFDYILLETTGLADPGAVASMFWVDAELGSDIYLDGIITIVDSKYGLKHLAEE-----------KPDGLINEATRQVALADAILINKTDLVPE--EDVKKLRATIRSINGLGQILETQRSRVDLSNVLDLHAFDSLSGISLQKKLQHVPGTQPHLDQSIVTITFEVPGNAKEEHLN-----MFIQNLLWEKN--------VRNKDNHCMEVIRLKGLVSIK-DKSQQVIVQGVHELYDLEETPVSWKDDTERTNRLVLLGRNLDKDILKQLFIATVTETEKQWTTHFKEDQVCT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0R0B1-1", "uniprot_id": "ZNG1_DANRE", "id": "B0R0B1-1", "name": "Zinc-regulated GTPase metalloprotein activator 1", "aln": "-------MEDEDE-----CPELVPIK------EKPSGP------------------------------TAQIPVTIITGYLGAGKTTLLNYILTEQHNKRIAVILNEFGEGSALEKSLAVSQAGELYEEWLELRNGCLCCSVKDNGLKAIENLMEKK-GKFDYILLETTGLADPGAVASMFWVDAELGSDVYLDGIVTVIDAKYGLQHLTEE-----------KPEGLINEAARQIALADLTIINKTDLVHE--TELLKLRDTVRSINALVKILETQKSRVDLSEVLDLHSFDTKDGERLTKKLQLVKTSQPHLDKSMLTITFEVPGSVSEDLLN-----IFIQELLWEKT--------FKNKAGLPMTVIRLKGILSLQ-QKQKKVMLQGVHELYELEETPEFWADQEPRLNRLVFIGRNLDGEILKKEFISAVSNKDSVE-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53729-1", "uniprot_id": "ZNG1_YEAST", "id": "P53729-1", "name": "Zinc-regulated GTPase metalloprotein activator 1", "aln": "-MSALRNIKFNEEEDGELPCLVTGEENNLQEILENVSYDGGNIVSDAKVERVNKQVENTSAGATDVHEKKRIPVSIITGYLGSGKSTLLEKIALKGADKKIAVILNEFGDSSEIEKAMTIKNGSNSYQEWLDLGNGCLCCSLKNIGVKAIEDMVERSPGKIDYILLETSGIADPAPIAKMFWQDEGLNSSVYIDGIITVLDCEHILKCLDDISIDAHWHGDKVGLEGNLTIAHFQLAMADRIIMNKYDTIEHSPEMVKQLKERVREINSIAPMFFTKYSDTPIQNLLDIHAYDS---VRISDILDSGSGNGTIHDDRMGTIMLTFRPLKNEEEYNNKFIKQFLQPLLWKNFGAMTVLGGRRRDDGRDWEVQRTKGLILIEGENPIARVIQGVRDTYDVFPG---KYDGSNKECKIVLIGKYLEKESIEELLRKTLE-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::: :. : : . :***:*:*****:**:***: * : .:::****** *:.* :**::::.:..: *:***:* *******:*: *::***:::::. **:* *****:*:***..::.*** * *.*.:*:***:*::*.:: *: * : :* :. * *:*:** ::** * : . : :*: :*.**.: :: *: * . :.::**:*::* : . *: . . *. : *: : . .*: * *:* ***:: :.. . * * **:: :: :: ::**::: :: * : ::*::*: *: : ::: : :: ", "identical_positions": 107, "similar_positions": 137, "identity": "23.52%" }, { "cls_id": "homologset.agr.SGD:S000005313", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VDB2-1", "uniprot_id": "ALG12_MOUSE", "id": "Q8VDB2-1", "name": "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "aln": "MAGKKSSGKRSWPLLGLLVTVATIHLVICPYTKVEESFNLQATHDLL-YHQLDIDKYDHHEFPGVVPRTFLGPLVIAAFSSPVVYVLSLLEVS---KFYSQLIVRGVLGLGVISGLWTLQKEVRQQFGATVA------------------VMFCWISATQFHLMFYCTRTLPN-VLALAVVLPALTAWLQRRWALFVWLSAFVIIGFRAELAMLLGIALLLTLYQRRLTVARVLRHAIPAGLLCLGLTVAVDSYFWRYLVWPEGVVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLG----AVDRRTYALALPSLGFVALYSLLPHKELRFIIYTFPVLNIMAARGCTYILN--KKSWPYKVRAMLVTGHILVN-VAYTATSLYVSHFNYPGGVAMQQLHELVPPQ--TDVLLHIDVAAAQTGVSRFLQVND---DWRYDKSEDVG--AAAMLNYTHILMEAVPG----HPALYRDTHRVLASIEGTTGISLNLMKLPPFDVNLQTKLVLLER---------------------------LLRPA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BV10-1", "uniprot_id": "ALG12_HUMAN", "id": "Q9BV10-1", "name": "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "aln": "MAGKGSSGRRPL-LLGLLVAVATVHLVICPYTKVEESFNLQATHDLL-YHWQDLEQYDHLEFPGVVPRTFLGPVVIAVFSSPAVYVLSLLEMS---KFYSQLIVRGVLGLGVIFGLWTLQKEVRRHFGAMVA------------------TMFCWVTAMQFHLMFYCTRTLPN-VLALPVVLLALAAWLRHEWARFIWLSAFAIIVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWPEGKVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLG----LVDRRTHAPTVLALGFMALYSLLPHKELRFIIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGHLVVN-AAYSATALYVSHFNYPGGVAMQRLHQLVPPQ--TDVLLHIDVAAAQTGVSRFLQVNS---AWRYDKREDVQP-GTGMLAYTHILMEAAPG----LLALYRDTHRVLASVVGTTGVSLNLTQLPPFNVHLQTKLVLLER---------------------------LPRPS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VH78-1", "uniprot_id": "ALG12_DROME", "id": "Q9VH78-1", "name": "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "aln": "-------------MDILIFVTAAAHLVYTPFTKVEESFNLQAMHDIL-YLRNNFTQYDHHDYPGVVPRTFIGPLVVSIISAPFVLLFETLSIN---KFWAQYVVRLVLAGAISVAWNSLRQAVTKIYGVEVR------------------LWFTAITITQFHFMFYMTRPLPN-IFALPIVLFAIAYWLRDQHKPFIICSGISILVFRSELALFLGILLVVSLLRRKVSIDGLLKVALPAGVCILAATVLVDSFFWRRLLWPEGEVLWYNTVLNKSSNWGTSPFLWYFYSALPRAMGASLVLVPIGV---ALEPRIRPLVLSALLFVLLYSILPHKELRFIIYVFPVLNIAAACACQRIWMNSAKSTWHSFLALACGAHLLLN-VFITLFLLVISGTNYPGGAALSRLHRLEAGT--SNVSVHISNLAAQSGVSRFMEINN---EWTYSKDETMNYTQADLVAYTHLLVEAKNKQNTELWASLQNEFDTLEFIDCFNSIGIQYNSLLPVRIKTKPCIGILKKRPVAPKEASKTKEKIAKTKTYPVEKETLLAPVKEFPKVIGDPKMKSRLQVDADDDDGIVSTVEEMSLELETDTEPHAGAETIETPLKEINFQELRTLALGQATKKSRAATKMKIRQIIEQHYRAKGKQIENDSAETQKTQGKAGLRQSVKSIIKQEKIKEMIEQIATMDLTRICDLERTSTKDCLKQVIDKIDDSEGLKSK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53730-1", "uniprot_id": "ALG12_YEAST", "id": "P53730-1", "name": "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "aln": "--------MRWSVLDTVLLTVISFHLIQAPFTKVEESFNIQAIHDILTYSVFDISQYDHLKFPGVVPRTFVGAVIIAMLSRPYLYLSSLIQTSRPTSIDVQLVVRGIVGLTNGLSFIYLKNCLQDMFDEITEKKKEENEDKDIYIYDSAGTWFLLFLIGSFHLMFYSTRTLPNFVMTLPLTNVALGWVLLGRYNAAIFLSALVAIVFRLEVSALSAGIALFSVIFKKISLFDAIKFGIFGLGLGSAISITVDSYFWQEWCLPEVDGFLFNVVAGYASKWGVEPVTAYFTHYLRMMFMPPTVLLLNYFGYKLAPAKLKIVSLASLFHIIVLSFQPHKEWRFIIYAVPSIMLLGATGAAHLWENMKVKKITNVLCLAILPLSIMTSFFISMAFLYISRMNYPGGEALTSFNDMIVEKNITNATVHISIPPCMTGVTLFGELNYGVYGINYDKTENTTLLQEMWPSFDFLITHEPTASQLPFENKTTNHWELVNTTKMFTGFDPTYIKNFVFQERVNVLSLLKQIIFDKTP-------------------TVFLKELTANSIVKSDVFFTYKRIKQDEKTD-------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::... : **: *:********:** **:* * :: :*** .:********:*.:::: :* * : : . :. . .: * :** ::. . *:: : :. . * . .**:*** **.*** :::*.:. *: * . : *.: : ** *:. : . :.:: ::::: :: .: . . :: ***:**: ** : :*.* . :*:**..*. ** * : . ::: : : :* .: : *: **** *****..* : : .* .. : . . .: ::. : * :* ***** *: :: : ::. :**. .. :**: * ::* *.* * : .:: . : : .... . . . : : : : ", "identical_positions": 99, "similar_positions": 153, "identity": "13.69%" }, { "cls_id": "homologset.agr.SGD:S000005314", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08648-1", "uniprot_id": "M3K4_MOUSE", "id": "O08648-1", "name": "Mitogen-activated protein kinase kinase kinase 4", "aln": "MRDAIAEPVPPPALADTPAAAMEELRPAPPPQPEP-------DPECCPAARQECMLGESARKSMESDPEDFSDETNTETLYGTSPPSTPRQMKRLSAKHQRNSAGRPASRSNLKEKMNTPSQSPHKDLGKGVETVEEYSYKQEKKIRATLRTTERDHKKNAQCSFMLDSVAGSLPKKSIPDVDLNKPYLSLGCSNAKLPVSMPMPIARTARQTSRTDCPADRLKFFETLRLLLKLTSVSKKKDREQRGQENTAAFWFNRSNELIWLELQAWHAGRTINDQDLFLYTARQAIPDIINEILTFKVNYGSIAFSSNGAGFNGPLVEGQCRTPQETNRVGCSSYHEHLQRQRVSFEQVKRIMELLEYMEALYPSLQALQKDYERYAAKDFEDRVQALCLWLNITKDLNQKLRIMGTVLGIKNLSDIGWPVFEIPSPRPSKGYEPEDEVEDTEVELRELESGTEESDEEPTPSPRVPELRLSTDAILDSRSQGCVSRKLERLESEEDSIGWGTADCGPEA--SRHCLTSIYRPFVDKALKQMG-LRKLILRLHKLMNGSLQRARVALVKDDRPVEFSDFPGPMWGSDYVQLSGTPPSSEQKCSAVSWEELR--AMDLPSFEPAFLVLCRVLLNVIHECLKLRLEQRPAGEPSLLSIKQLVRECKEVLKGGLLMK--QYYQFMLQEVLGGLEKTDCNMDAFEEDLQKMLMVYFDYMRSWIQMLQQLPQASHSLKNLLEEEWNFTKEITHYIRGGEAQAGKLFCDIAG--MLLKSTGSFLESGLQESCAELWTSADDNGAADELRRSVIEISRALKELFHEARERASKALGFAKMLRKDLEIAAEFVLSASARELLDALKAKQYVKVQIPGLENLHVFVPDSLAEEKKIILQLLNAATGKDCSKDPDDVFMDAFLLLTKHGDRARDSEDGWGTWEARAVK--IVPQVETVDTLRSMQVDNLLLVVMESAHLVLQRKAFQQSIEGLMTVRHEQTSSQPIIAKGLQQLKNDALELCNRISDAIDRVDHMFTLEFDAEVE-ESESATLQQYYREAMIQGYNFGFEYHKEVVRLMSGEFRQKIGDKYISFAQKWMNYVLTKCESGRGTRPRWATQGFDFLQAIEPAFISALPEDDFLSLQALMNECIGHVIGKPHSPVT----AIHRNSPRPVKVPRCHSDPPNPHLIIPTPEGFSTRSVPSDARTHGNSVAAA--AAVAAAATTAAGRPGPGGGDSVPAKPVNTAPDTRGSSVPENDRLASIAAELQFRSLSRHSSPTEERDEPAYPRSDSSGSTRRSWELRTLISQTKDSASKQGPIEAIQKSVRLFEERRYREMRRKNIIGQVCDTPKSYDNVMHVGLRKVTFKWQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPND--HKTIKETADELKIFEGIKHPNLVRYFGVELHREEMYIFMEYCDEGTLEEVSRLG--LQEHVIRLYTKQITVAINVLHEHGIVHRDIKGANIFLTSSGLIKLGDFGCSVKLKNN----------------------------AQTMPGEVNSTLGTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTGKRPWHEYEHNFQIMYKVGMGHKPPIP--ERLSPEGKAFLSHCLESDPKIRWTASQLLDHAFVKVCTDEE--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZUS1-1", "uniprot_id": "A0A8I5ZUS1_RAT", "id": "A0A8I5ZUS1-1", "name": "Mitogen-activated protein kinase kinase kinase 4", "aln": "MRDAIAEPVPPPALAVNPAAAMEEPRPAPPPQPEP-------ESECCPAARQEHMLGESARKSLESDPEDFSDETNTENLYGTSPPSTPRQMKRLSAKHQRNSAGRPASRANLKEKMNTPSQSPHKDLGKGVEAVEEYSYKQGKKTRATLRTTERDHKKNAQCSFMLDSVAGSLPKKSIPDVDLNKPYLSLGCSNAKLPVSMPMPIARTARQTSRTDCPADRLKFFETLRLLLKLTSVSKKKDREQRGQENTAAFWFNRSNELIWLELQAWHAGRTINDQDLFLYTARQAIPDIINEILTFKVNYGSAAFSRNGAGFNGTSLEGQCRTLHGTNSLGCSTYHEHLQRQRVSFEQVKRIMELLEYMEALYPSLQALQKDYERYAAKDFEDRVQALCLWLNITKDLNQKLRIMGTVLGIKNLSDIGWPVFEIPSPRPSKGYEPEEEGEDTEGELRELESGTEESDEERSPNPRVPELRLSADTILDSHSQGCASRKLERLESEEDSVGWGIADCGPEA--SRHCLTSIYRPFVDKALKQMG-LRKLILRLHKLMNGSLQRARVALVKDDRPVEFSDFPGPMWGSDYVQLSGTPPSSEQKCSAVSWEELR--AMDLPSFEPAFLVLCRVLLNVIHECLKLRLEQRPAGEPSLLSIKQLVRECKEVLKGGLLMK--QYYQFMLQEVLDGLEKTDCNMDAFEDDLQKMLMVYFDYMRSWIQMLQQLPQASHSLKNLLEEEWNFTKEITHYIRGGEAQAGKLFCDIAG--MLLKSTGSFLDSGLQESCAELWISADDNGAADELRRSVIEISRALKELFHEARERASKALGFAKMLRKDLEIAAEFVLSASARELLDVLRAKQYVKVQIPGLENLHVFVPDSLAEEKKIILQLLNAATGKDCSKDPDDVFVDAFLLLTKHGDRARDSEDGWSTWEARAIK--IVPQVETVDTLRSMQVDNLLLVVMESAHLVLQRKAFQQSIEGLMTVHHEQTSSQPVIAKALQQLKNDALELCNRISDAIDRVDHMFTLELDAEVE-ESESATLQQYYREAMIQGYNFGFEYHKEVVRLMSGEFRQKIGDKYISFAQKWMNYVLTKCESGRGTRPRWATQGFDFLQAIEPAFISALPEDDFLSLQALMNECIGHVIGKPHSPVT----AIHRNSPRPVKVPRCHSDPPNPHLIIPTPEGFSTRSVPSDTRNHGNSVAAAAVAAAAAAATTAAGRPGPGGGDSAPAKPVNTAPDTRGSSVPENDRLASIAAELQFRSLSRHSSPTEERDEPAYPRSDSSGSTRRSWELRTLISQTKDSASKQGPIEAIQKSVRLFEERRYREMRRKNIIGQVCDTPKSYDNIMHVGLRKVTFKWQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPND--HKTIKETADELKIFEGIKHPNLVRYFGVELHREEMYIFMEYCDEGTLEEVSRLG--LQEHVIRLYSKQITVAINVLHEHGIVHRDIKGANIFLTSSGLIKLGDFGCSVKLKNN----------------------------AQTMPGEVNSTLGTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTGKRPWHEFEHNFQIMYKVGMGHKPPIP--ERLSPEGKDFLSHCLESDPKIRWTASQLLDHAFVKVCVIAPSSCPRECVVILDLSLCLEQW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6R4-1", "uniprot_id": "M3K4_HUMAN", "id": "Q9Y6R4-1", "name": "Mitogen-activated protein kinase kinase kinase 4", "aln": "MREAAAALVPPPAFAVTPAAAMEEPPPPPPPPPPPPEPETESEPECCLAARQEGTLGDSACKSPESDLEDFSDETNTENLYGTSPPSTPRQMKRMSTKHQRNNVGRPASRSNLKEKMNAPNQPPHKDTGKTVENVEEYSYKQEKKIRAALRTTERDRKKNVQCSFMLDSVGGSLPKKSIPDVDLNKPYLSLGCSNAKLPVSVPMPIARPARQTSRTDCPADRLKFFETLRLLLKLTSVSKKKDREQRGQENTSGFWLNRSNELIWLELQAWHAGRTINDQDFFLYTARQAIPDIINEILTFKVDYGSFAFVRDRAGFNGTSVEGQCKATPGTKIVGYSTHHEHLQRQRVSFEQVKRIMELLEYIEALYPSLQALQKDYEKYAAKDFQDRVQALCLWLNITKDLNQKLRIMGTVLGIKNLSDIGWPVFEIPSPRPSKGNEPEYEGDDTEGELKELESSTDESEEEQISDPRVPEIRQPIDNSFDIQSRDCISKKLERLESEDDSLGWGAPDWSTEAGFSRHCLTSIYRPFVDKALKQMG-LRKLILRLHKLMDGSLQRARIALVKNDRPVEFSEFPDPMWGSDYVQLSRTPPSSEEKCSAVSWEELK--AMDLPSFEPAFLVLCRVLLNVIHECLKLRLEQRPAGEPSLLSIKQLVRECKEVLKGGLLMK--QYYQFMLQEVLEDLEKPDCNIDAFEEDLHKMLMVYFDYMRSWIQMLQQLPQASHSLKNLLEEEWNFTKEITHYIRGGEAQAGKLFCDIAG--MLLKSTGSFLEFGLQESCAEFWTSADDSSASDEIRRSVIEISRALKELFHEARERASKALGFAKMLRKDLEIAAEFRLSAPVRDLLDVLKSKQYVKVQIPGLENLQMFVPDTLAEEKSIILQLLNAAAGKDCSKDSDDVLIDAYLLLTKHGDRARDSEDSWGTWEAQPVK--VVPQVETVDTLRSMQVDNLLLVVMQSAHLTIQRKAFQQSIEGLMTLCQEQTSSQPVIAKALQQLKNDALELCNRISNAIDRVDHMFTSEFDAEVD-ESESVTLQQYYREAMIQGYNFGFEYHKEVVRLMSGEFRQKIGDKYISFARKWMNYVLTKCESGRGTRPRWATQGFDFLQAIEPAFISALPEDDFLSLQALMNECIGHVIGKPHSPVTGLYLAIHRNSPRPMKVPRCHSDPPNPHLIIPTPEGFSTRSMPSDARSHGSPAAAA----AAAAAAVAASRPSPSGGDSVLPKSISSAHDTRGSSVPENDRLASIAAELQFRSLSRHSSPTEERDEPAYPRGDSSGSTRRSWELRTLISQSKDTASKLGPIEAIQKSVRLFEEKRYREMRRKNIIGQVCDTPKSYDNVMHVGLRKVTFKWQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPND--HKTIKETADELKIFEGIKHPNLVRYFGVELHREEMYIFMEYCDEGTLEEVSRLG--LQEHVIRLYSKQITIAINVLHEHGIVHRDIKGANIFLTSSGLIKLGDFGCSVKLKNN----------------------------AQTMPGEVNSTLGTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTGKRPWHEYEHNFQIMYKVGMGHKPPIP--ERLSPEGKDFLSHCLESDPKMRWTASQLLDHSFVKVCTDEE--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53599-1", "uniprot_id": "SSK2_YEAST", "id": "P53599-1", "name": "MAP kinase kinase kinase SSK2", "aln": "MSHSDYFNYKPYGDSTEKPSSSKMRQSSSSSSSRLR------SESLGRNSNTTQARVASSPISPGLHSTQYFRSPNAVYSPGESPLNTVQLFNRLPGIPQGQFFHQNAISGSSSSSARSSRRPSNIGLPLPKNPQQSLP-KLSTQPVPVHKKVEASKTESEIIKKPAPVNSNQDPLLTTPTLVISPELASLNTTNTSIMSTPQNITNQTSNKHIPTRSQPNGSTSSSTLQDIVTTNSSQR-----SVGHHGGSTTSLRTYKKQYVLNEQLYLRKMRNRANDDYYTRGIVASSNFEDDEENFSNKGEDDLELEMDDLLKVEGEDKDNDFNFGYNFITSSTKNN----ENVVSMSLNYLKGKLDWLRDVNNDQPCEIEDEEWHSILGSEDLLSKLLQNPMVNNRFEWQTMLSKVLKGDIVRNEK----TKIANQGKGPGFNTQFS-DDIWIELKAWMNGRTVEDQNKS----LRIFRDSTDSVFQEIMAFKLEDNMSADEAAETIKSLVDKYYRVLN-----LWPNIKRMHAEKPITKTEAFRNRIDTLNSWLNFKFNFDTNIAYLKKWIVGNKELESTTEVDNTTVNLDDPAVFATNCKRFAEQIMKEKDIELIFQKKIFFPLAPWILKAKFFFLKYQKTWNELNLSYLDQDLEFLLMFPMRLVKDIILIRLSYAKKIQNPTLMMIDQMMDDFSTYIKLAVQMKFTVASYCNDWFFKVKIDPEFDHTVVEGLEYFFSILELRILYSGKNSFKTSKEPDLLLKYWEMFRNVGYYIDDAGELIAAEFTKLTLRLVHRLHAYLLRQQNTPPKLENEAAAEKWLVQIFEILGSMKRKLNRFTNILTKAFQNFVRYKIEDHNYLLKQLKETGHFLIYTGGYLEQNGTYLIGSPELLGCKD----------DDILRIIKNSDIGCDLVPKLEINNSLTIYNALDDNWNSNSSLGSDISNDGTPFYYIKNDLTTQPRSYNGNRVNREPDFENSRSTEEEFYELETRLNSLGYVLVLTPQEPLLWEGEMYNLSDNKTIKPEGLNLKVIPNSIDLMCQGSSYALEYQCDRFQQISGSSVSFLEKKSS------SETVKNNLQRINKAYFRCTYSVLKNYTKIVTTFKKVSPVNDLLNNIFLFGRDFGLNFLRIN---------VANNEKRSIIILLMMR------LSIGWLKFLAEDCDPTDQRVFRWCVTSM-----EFAMHMVSGWN------------ILALDECQFSSLKQKISECMSLLISHFDIIGARSIEVEKINQQARSN-------------LDLEDVFDDDMMLQVNSEFRVQSIMELEERIKRNPHQTGKVIDDSDKGNKYLVSLASSISNVSMRWQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANLDNEWAIMYHVAAGHTPQFPTKDEVSSAGMKFLERCLIQNPSKRASAVELLMDPWIVQIREIAFGDDSSSTDTEERE------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .: * . : .:: : ..... . . . :. *: * . :: ..*: * ** .* : ::*:. * : : * .. ... .:. :..: . : :. . * .: .. :..* .:.:. . ... * : * : :. **. :*:.: : :.:.: * . .: . .**: ::. .* .: . *:.. : :. :: *: * : . :* : . * .:: :: .*. . . :: : : : : *: :: :.* .:: : *:::. : . . :* * :: . :* :. * :.: :: : : .: * .: :*.. . * :.: . :* **: .. .::: : :* . * :: . ::. *: : . ..* * ..:*.:.: :*: * *:. :: .:: .. * .:: .. .: . *. :*. .: : :: ::* : *: *. :*:. . ** : . . . * . ::: * .::: .* : : : .* ::: ::.:: . :* :. .* ..*: :: *: .*:: : ** :.: : * .. ::.* : :::..* ::: . : .**: : . : : . * *.: : : : :::.*: ::: .* . : :. ::*: *: :: ::. . * :: . :: : ** * * : *:.* . * :: .: : : :: .:* * :: . . .*. * :::: . . . .:. *:: : : :*:. . * .:.: ..*:. . : :. *. . .: : * ** .:.:**: : .: :**. . : .* : * .: : . : * : . :. * .:* .. * :*:*. *:.. :* : : : : .*. *.: : * * : :: . *:* * . .:: * .:. : : : : **: :: . :* :. :* .*: :: * .. * . .* * :*: :**: *: ::.. : : .*. :.* : .: :*:::**: * ** * :*:**:.:.:*.**::*:***.:* .. :* : :*:.::* ::***:* *:***:**::: ******: *:* : . * :* * ::*: *: .: *** ******:* **:* .*:** ***.: *: ** .:. . : . :**. ***** ** :. :*: * *:*******:**:**:*** : :::: ***:*. **.* :* :.:*. * **.:** .:*. * :* :** ..:: ", "identical_positions": 250, "similar_positions": 572, "identity": "14.92%" }, { "cls_id": "homologset.agr.SGD:S000005317", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P85971-1", "uniprot_id": "6PGL_RAT", "id": "P85971-1", "name": "6-phosphogluconolactonase", "aln": "--------------MAAPAPGLISVFSSPQE-LGASLAQLVAQRAASCLEG------------------------------------NRGRFALGLSGGSLVSMLARDLPAATAPAGPASFARWTLGFCDERLVPFDHAESTYGLYRTHLLSKLP-----IPDSQVLTIDPALPVEDAAEDYARKLRQAFQGD---TVPVFDLLILGVGPDGHTCSLFPGHP-LLQEREKIVAPIGDSPKPPPQRVTLTLPVLNAAQSVIFVATGEGKAAVLKRILEDQE-SALPAAMVQP-RTGALCWFLDEAAARLLSVPFEKHSTL-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ60-1", "uniprot_id": "6PGL_MOUSE", "id": "Q9CQ60-1", "name": "6-phosphogluconolactonase", "aln": "--------------MAAPAPSLISVFSSPQE-LGASLAQLVAQRAASCLEG------------------------------------DRGRFALGLSGGSLVSMLARDLPAAAAPAGPASFARWTLGFCDERLVPFDHAESTYGLYRTHLLSKLP-----IPDSQVLTINPALPVEDAAEDYARKLRQALQGD---AVPVFDLLILGVGPDGHTCSLFPDHP-LLQEREKIVAPISDSPKPPPQRVTLTLPVLNAAQSIIFVATGEGKAAVLKRILEDKE-GTLPAALVQP-RTGALCWFLDEAAARLLSVPFEKHSTL-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95336-1", "uniprot_id": "6PGL_HUMAN", "id": "O95336-1", "name": "6-phosphogluconolactonase", "aln": "--------------MAAPAPGLISVFSSSQE-LGAALAQLVAQRAACCLAG------------------------------------ARARFALGLSGGSLVSMLARELPAAVAPAGPASLARWTLGFCDERLVPFDHAESTYGLYRTHLLSRLP-----IPESQVITINPELPVEEAAEDYAKKLRQAFQGD---SIPVFDLLILGVGPDGHTCSLFPDHP-LLQEREKIVAPISDSPKPPPQRVTLTLPVLNAARTVIFVATGEGKAAVLKRILEDQEENPLPAALVQP-HTGKLCWFLDEAAARLLTVPFEKHSTL-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZ64-1", "uniprot_id": "6PGL_DROME", "id": "Q9VZ64-1", "name": "Probable 6-phosphogluconolactonase", "aln": "--------------MSEKKGALKVIPSASEEQLVQALGDLLQRCSQEALA-------------------------------------KHDKFSVGLSGGSLVQLLTKALKSCNLKT-----AKWVFFFCDERYVRLDDSDSTYGAYRAEWLTQLPC----IQESQFVRADTSQPLDACAADYEAKVKSQVDR--------FDLLLLGMGPDGHTCSLFPEQPATLQETKRLVIPIRNSPKPPPERITFTLPLINKARNVAFVVTGAAKASVVKSVFVDLD-KKFPAAWVNP-TKGQLTLIVDAGAGKEIETLK-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50278-1", "uniprot_id": "SOL1_YEAST", "id": "P50278-1", "name": "6-phosphogluconolactonase-like protein 1", "aln": "MTTTVPKVFAFHEFAGVAEAVADHVIHAQNSALKKGKVSRSTQMSGTSLNGNGNTESKTMERVNSVRSNASSRGGSEDGATKKLKKEKERRFKIALSGGSLIQVLHEGLLKRDDVQ----WGKWDIYFADERLVPFSSSESNYGLAKRKIFDLIDTEKYGTPKIYHIDESLINDPQECADNYEKILIKGFAGRDSVKLPMFDLFLLGCAPDGHIASLFPNFQENLRENLAWVIPVENAPSGPSNRISLTIPVICHSHRVTFVVEGATKAPVIKTIMERPE-KGLPSSIVNEGAAGRVSWFVDDDALKDVFVIKKKYKFYDDENLTE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : :. * . . : : .* . :* :.******:.:* . * .:* : *.*** * :. ::*.** : . : : . : . : .* :* : . . ***::** .**** .**** *:* * *: ::*. *.:*:::*:*:: :: : **. * **.*:* :: : :*:: *: * : ::* * : : . ", "identical_positions": 56, "similar_positions": 76, "identity": "17.18%" }, { "cls_id": "homologset.agr.SGD:S000005318", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O15144-1", "uniprot_id": "ARPC2_HUMAN", "id": "O15144-1", "name": "Actin-related protein 2/3 complex subunit 2", "aln": "MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSISLKFYKELQAHGAD------ELLKRVYG-----SFLVNPESGYNVSLLYDLENLPAS-KDSIVHQAGMLKRNCFASVFEKYFQFQEE---------------GKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGR---RASHTAPQVLFSHREPPLELK---DTDAAVGDNIGYITFVLFPRHTN-ASARDNTINLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARPDAEKK------EMKTITGKTFSSR----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CVB6-1", "uniprot_id": "ARPC2_MOUSE", "id": "Q9CVB6-1", "name": "Actin-related protein 2/3 complex subunit 2", "aln": "MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSISLKFYKELQAHGAD------ELLKRVYG-----SFLVNPEPGYNVSLLYDLENLPAS-KDSIVHQAGMLKRNCFASVFEKYFQFQEE---------------GKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGR---RASHTAPQVLFSHREPPLELK---DTDAAVGDNIGYITFVLFPRHTN-ATARDNTINLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARPDAEKK------EMKTITGKTFSSR----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P85970-1", "uniprot_id": "ARPC2_RAT", "id": "P85970-1", "name": "Actin-related protein 2/3 complex subunit 2", "aln": "MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSISLKFYKELQAHGAD------ELLKRVYG-----SFLVNPESGYNVSLLYDLENLPAS-KDSIVHQAGMLKRNCFASVFEKYFQFQEE---------------GKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGR---RASHTAPQVLFSHREPPLELK---DTDAAVGDNIGYITFVLFPRHTN-ATARDNTINLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARPDAEKK------EMKTITRKTFSST----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VIM5-1", "uniprot_id": "ARPC2_DROME", "id": "Q9VIM5-1", "name": "Actin-related protein 2/3 complex subunit 2", "aln": "MILLEINNRIIEETLLVKYRNAQAGLKPESIDIRIADFDGVLYHISNVNGDKTKVRISISLKFYKQLQEHGAD------ELLKREYG-----SLLTDTEEGYNVSVLINLEEIPED-CEQIAKRIGLLKRNCFASVFEKYFDYQEQ---------------GEEGQKRAVINYRNDETLYVEAKPDRVTVVFSTIFRDEDDVIIGKVFMQELREGR---RASHTAPQVLFSHREPPLELA---NTDARVGDNIGYVTFVLFPRHTN-KETRDNTINLIHMFRDYLHYHIKCSKAYIHSRMRAKTSDFLKVLNRARPEPKNT------EKKTITGRTFKRID---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53731-1", "uniprot_id": "ARPC2_YEAST", "id": "P53731-1", "name": "Actin-related protein 2/3 complex subunit 2", "aln": "MLHLQPQNLLIQKTLNEAIEALRKG-SPLTMDRIVSDFDYTTYHISNTAEDKSILLLSVKTKAWVSVSECQLDGSLTLLKFLADHYSSLGGVTIPSEVEPGYDYTLQITLAELVQESILQLSVLKTIILSFPFELAISKFIELSQQQPAPVEAEITGGEVAANGDNTLFTIKYRDEENIFIKPSNDRVTIIFETIFQDETDKIFGKVFLQEFVDARKRNRQIQSAPQVLYSH-EPPLELKRLYQPPKVAEQSRRFITFVLFPRHFQTKELQFHSICQLTLFRNYFHYHIKCSKAYMHSRMRFRVDSFIKVLNRAKVDEDDENDELSAEGRQQARRTFTGRKIVY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *: :* :*::** . * .* ::: .:*** . ***** **: : :*:. * : .:. * ::* *. :: : * **: :: * :: . .: :: * .:.*::: .:: .: .:. .*:**::*.::::.. ****::*.*:*:*: * ::****:**: :.* * ::*****:** ****** :. . :. ::******** : : ::* : **:*:**********:*:*** :...*:******: : .. * : : :**. ", "identical_positions": 99, "similar_positions": 108, "identity": "28.78%" }, { "cls_id": "homologset.agr.SGD:S000005319", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQX3-1", "uniprot_id": "D3ZQX3_RAT", "id": "D3ZQX3-1", "name": "Small ribosomal subunit protein uS12m", "aln": "MSWPGLLHGLTTS---LSRGLALAPQLWATRSMATLNQMHR-LGRPKEPPKRLGP-TEGRPQLKGVVLRTFIRKPKKPNSANRKCCRVRLSTGKEAVCFIPGEGHTLQEHHVVLVEGGRTQDLPGVKLKVVRGKYDCGHVQ-----------KKK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35680-1", "uniprot_id": "RT12_MOUSE", "id": "O35680-1", "name": "Small ribosomal subunit protein uS12m", "aln": "MSWPGLLYGLTTS---LSRGLALAPQLWAARSMATLNQMHR-LGPRKEPPKRLGP-TEGRPQLKGVVLRTFIRKPKKPNSANRKCCRVRLSTGKEAVCFIPGEGHTLQEHHVVLVEGGRTQDLPGVKLKVVRGKYDCGHVQ-----------KKK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15235-1", "uniprot_id": "RT12_HUMAN", "id": "O15235-1", "name": "Small ribosomal subunit protein uS12m", "aln": "MSWSGLLHGLNTS---LTCGPALVPRLWATCSMATLNQMHR-LGPPKRPPRKLGP-TEGRPQLKGVVLCTFTRKPKKPNSANRKCCRVRLSTGREAVCFIPGEGHTLQEHQIVLVEGGRTQDLPGVKLTVVRGKYDCGHVQ-----------KK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F8G8-1", "uniprot_id": "E7F8G8_DANRE", "id": "E7F8G8-1", "name": "Small ribosomal subunit protein uS12m", "aln": "MAFLGSLKPMLSSALQASRSVSLWSAPLFSRTMATLNQMHR-KGKPPPPRRKISA-TFGHPQLKAVVLKTMIRKPKKPNSANRKCAQVRLSNGQEAVVYIPGEGHNLQEHNVVLVQGGRTQDLPGVKLAVIRGKYDCAHVV-----------KKKQ--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P10735-1", "uniprot_id": "RT12_DROME", "id": "P10735-1", "name": "Small ribosomal subunit protein uS12m", "aln": "MNFLRQSFGITKQ---LASQAIQCSYETAVRGMASLQQMHR-SGPHIKTRPPRQP-LDGKPFAKGVVLKTLIKKPKKPNSANRKCVLVRLSTGKEMVAYIPGIGHNLQEHNIVLCRVGRLQDVPGVKLKAVRGVYDLAHVV-----------KKSQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53732-1", "uniprot_id": "RT12_YEAST", "id": "P53732-1", "name": "Small ribosomal subunit protein uS12m", "aln": "MLSRFMSNTWCTP---LRQAQRLFSSTTTMQ--ATLNQIKRGSGPPRRKKISTAPQLDQCPQRKGVVLRVMVLKPKKPNSAQRKACRVRLTNGNVVSAYIPGEGHDAQEHSIVYVRGGRCQDLPGVKYHVIRGAGDLSGVVNRISSRSKYGAKKPSKS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . *:*:*::* * . * *.*** .: ********:**. ***:.*. :*** ** *** :* . ** **:**** .:** * . * ** ", "identical_positions": 48, "similar_positions": 22, "identity": "30.38%" }, { "cls_id": "homologset.agr.SGD:S000005321", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P9R1-1", "uniprot_id": "DDX51_MOUSE", "id": "Q6P9R1-1", "name": "ATP-dependent RNA helicase DDX51", "aln": "----------------------------------------------------MALFHIARYAGP---EAAGQGDTDAEAGSRARVLLERLQNRARERQQREPELETTGTAGEGEAAAAGKRRRRPRRRR-RVSGSATPNSEAPRAKRRKADKD-------------VDAGRGEEAPEELSAG--AEDPGANPQ-------------EDVQRPPAPGRVLGDFARRKTPKVQPFLPAWLAKPSCVK------KSVTEDLTPIEDIPEVHPDLQKQLRANGITSYFPVQAAVIPALLESADHGFLIGRGGYQP--SDLCVSAPTGSGKTLAFVIPVVQALLHRVVCHIRALVVLPTKELAQQVSKVFNIYTDTTPLRVALVTGQKSLAKEQESLVQKTADGFRCLADIVVATPGRLVDHIDQTPGFSLQQLRFLIIDEADRMIDSMHQSWLPRVVAAAFYSEGPTGSCALLQRTQPQALTAASTCVPQMPLQKLLFSATLTQDPEKLQRLGLYQPRLFSTRLGQQSPKDTAEVDENS----------GKYTFPVGLTHHYVPCRLSSKPLIVLHLVLRMSCS----RALCFTNSRENSHRLYLLAQAFGG---VSVAEFSSRYGPGQRKKILKQFEQG----KIQLLISTDATARGIDVQGVELVINYDAPQYLRTYVHRVGRTARAGKTGQAFTLLLKVQERKFLQMVSEAGVPELTHHEIPRKLLQPLVARYETALSQLEKTVKEEQKLKAA------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K4S4-1", "uniprot_id": "A0A0G2K4S4_RAT", "id": "A0A0G2K4S4-1", "name": "ATP-dependent RNA helicase", "aln": "MPVAAPCCRQLLPGTDVCAKCSRTRDVTSASRSQGWLTSSKSVEEEPRRAAAMALFHIARYAGP---EAAGLGDTEAEAGGRARVLLERLQNRAREREQRQPELESTGTA----AEAPVRRRRRPRRRR-GVSGSVAEKPEAPRAKRQKVEDD-------------VDAGRGEETPEELSES--AEDPGESPQ-------------EDVQRPPAPGRVLGDFARKKVPKVQPFLPAWLAKPSCVK------KSVTEDLTPIEDIPEVHPDLQKQLRANGISSYFPVQAAVIPALLESADNGFLVGRGGYQP--SDLCVSAPTGSGKTLAFVIPVVQALLHRVVCHIRALVVLPTKELAQQVSKVFNIYTDTTPLRVALVTGQKSLAKEQESLVQKTADGFCCLADIVVATPGRLVDHIDQTPGFSLQQLRFLIIDEADRMIDSMHQSWLPRVVAAAFYTEDPTGSCALLQRTQPQAVTAASTCIPQMPLQKLLFSATLTQNPEKLQRLGLYQPRLFSTRLGHQSPRDTVEVDENL----------GKYTFPVGLTHHYVPCRLSSKPLIVFHLVLGMNFS----RALCFTNSRENSHRLFLLAQAFGG---VSVAEFSSRYGPGQRKKILKQFEQG----KIQLLISTDATARGIDVQGVELVINYDAPQYLRTYVHRVGRTARAGKTGQAFTLLLKVQERKFLQMVSEAGVPELACHEVPRKLLQPLVARYETALSQLEKTVKEEQKLKAA------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N8A6-1", "uniprot_id": "DDX51_HUMAN", "id": "Q8N8A6-1", "name": "ATP-dependent RNA helicase DDX51", "aln": "----------------------------------------------------MALFYVARYPGPDAAAAAGPEGAEAGAHGRARALLERLQSRARERQQQREPAQTEAAAS---TEPATRRRRRPRRRR-RVNDAEPGSPEAPQGKRRKADGEDAGAESNEEAPGEPSAGSSEEAPGEPSAGSSEEAPGERSTSASAEAAPDGPALEEAAGPLVPGLVLGGFGKRKAPKVQPFLPRWLAEPNCVR------RNVTEDLVPIEDIPDVHPDLQKQLRAHGISSYFPVQAAVIPALLESAACGFLVGRGGYRP--SDLCVSAPTGSGKTLAFVIPVVQALLSRVVCHIRALVVLPTKELAQQVSKVFNIYTDATPLRVSLVTGQKSLAKEQESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGFSLQQLRFLIIDEADRMIDSMHQSWLPRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQMPLQKLLFSATLTQNPEKLQQLGLHQPRLFSTGLAHRGLEDT-DGDGDS----------GKYAFPVGLTHHYVPCSLSSKPLVVLHLVLEMGFS----RVLCFTNSRENSHRLFLLVQAFGG---VDVAEFSSRYGPGQRRMILKQFEQG----KIQLLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAGKTGQAFTLLLKVQERRFLRMLTEAGAPELQRHELSSKLLQPLVPRYEEALSQLEESVKEERKQRAA------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DRI7-1", "uniprot_id": "DDX51_DANRE", "id": "Q6DRI7-1", "name": "ATP-dependent RNA helicase DDX51", "aln": "----------------------------------------------------MALFTINRYLGE-------EEEEDSEKQSRSKALLAKLQKQVKARGQQSVSNTPKEEEEQQDDKEHKKRKHKLQETKGKIKKSESVQNTDPTEEADSSVKKKKKRKKSLSTEDVIVKIEENESENEKSVDITGPTPSSPVQFKAEK------AEELTSSSQSNYQVLGGFKEKDVQKVKRVLPQWLSQPDVIQ------KDIKSNLIPISEVPGICPTLLRKLQTNGIQSFFPVQAEVIPAILESVGSGLLVGPGGYRP--RDVCVSAPTGSGKTLAFVIPVVQALSKRVVRQVRALAVLPTKELAQQVSNVFSAYTEGSSLKVVMITGQKSFAAEQTALSEIRGGVSHSMADIVVATPGRLVDHINKNSSFSLQHLRFLIIDEADRMIDSMHQSWLSQVTKAVYSTPGET-HTSVFRRTVPGPITAASLSPPQIPLQKLLFSATLTQNPEKLQLLDLHQPRLFSS---THSLTDNPAQSQD------------TFHFPQGLSEYYVPCTFSKKPLIILHFLLRLKFS----PALCFTNSREGAHRLYLLVKLFGG---VEVAEFSSKLSPGERQKTLKDFEKG----KIPLLISTDAAARGIDINGVKCVINYDAPQYIRTYIHRVGRTARAGKAGLAFTFLLKVQEKRFLKMVSDAGSPGIQKQHVHPEALKSMESRYEQVLAELGTIVKEENEKKRF------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P26802-1", "uniprot_id": "DDX51_DROME", "id": "P26802-1", "name": "Probable ATP-dependent RNA helicase Dbp73D", "aln": "----------------------------------------------------MELFTVNRYTEDLK-----EQKDGAQGTNNEDEILQKLLKKAAKRKRKHEAIEVVETP---------------------ILEKETSDVKESESKEEQVEEP--------------------------------EKPLEVVQ-------------EEDVPSNEFQVLGGDDSAAKKKKVQMQLPNWLAHPTIIEGGSLQPEEEVPASEAIDQLDYLEKYTCQALKQMKIKRLFPVQKQVIPWILEAHAK-----PPPFRP--RDICVSAPTGSGKTLAFAIPIVQLLSQRVDCKVRALVVLPVAELALQVYRVISELCSKTELEVCLLSKQHKLEDEQEKLVEQYKGKYYSKADIVVTTPGRLVDHLHATKGFCLKSLKFLVIDEADRIMDAVFQNWLYHLDSHVKET-----TDQLLAGTQAPLCYAELQASFGKQPHKLLFSATLSQDPEKLQDLRLFQPRLFATVLTMPVLKDATEEGADTEALTDPGQFVGRYTTPAELTEQYCVTELRLKPLTVFALVEKYKWK----RFLCFTNSSDQATRLTFVLKVLFQKYSTKVSELSGNLSAKVRNERLRDFAAG----KINGLICSDALARGIDVADVDVVLSYETPRHITTYIHRVGRTARAGRKGTAVTVLTEQDMTLFKKILSDANKGLGEEIHVSPDIEIQHAVEYKEALAGLRSEKVKNKNQKMAEKNRVATKALIHKKQEETATVRPLTLMEKLQIKANEIVQSSKKSSETKNSKTKADKTKYQPKETKKQIIAKQLKAIEN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53734-1", "uniprot_id": "DBP6_YEAST", "id": "P53734-1", "name": "ATP-dependent RNA helicase DBP6", "aln": "--------------------------------------------------MFASRFDPSQLTAP-------AASAPEGIVGTTPPAIVPLKRQATESDNEEYGSHQDSDESSNSSSEEDEDRMQVDYGASEEDSSEVEEEESKPSTHSTVLSR------------FKQTVSLQERLGASDIAESKEDEGIEDEAAS----------THQLKQIPQPEFVKNPMNLNTNSLQFKSTGWLNTEKIYY-------DNSLIKPFSDYANELEAKLLQNICKNFSTNTFPIQSIILDSILPVLNFTLNVSKRNFTRRIGDILVNAATGSGKTLAYSIPIVQTLFKRQINRLRCIIIVPTKLLINQVYTTLTKLTQGTSLIVSIAKLENSLKDEHKKLSNLEP-------DILITTPGRLVDHLN-MKSINLKNLKFLIIDEADRLLNQSFQGWCPKLMS---------------------HLKTDKLDTLPGNVIKMIFSATLTTNTEKLNGLNLYKPKLFLKQTDKLYQLPNKLNEFNIN-------IPTAKSVYKPLILLYSICQFMAHSPIAAKILIFVKSNESSIRLSKLLQLICESRSQSSVLKNLQN-LAVSINSVNSNNSKAENKKIVANFSHHSESAGITILITTDIMSRGIDINDITQVINYDPPMSSQQYVHRVGRTARANELGSAYNLLVGRGERTFFDDLNKDLDRDGKSVQPLELDFTLLESDSELYTSSLESLKNYHNNTAQA------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . : * :. .. . . . . .:: . ** . . : : : **:* :: :* : *: *.*.********: **:** * * ::*.: ::*. * ** .:. . : * * : . ::.: *: * : **:::********:. .: *: *:**:******::: .*.* :: : *::*****: :.***: * *.:*:** . : * * : :. :: . : : : : : : ..: ..... . .. : :* * ** :* :****: .: *:.*:.* *:*********.. * * ..* * :.. . : : * ..: ", "identical_positions": 99, "similar_positions": 127, "identity": "11.93%" }, { "cls_id": "homologset.agr.SGD:S000005324", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q499N4-1", "uniprot_id": "COQ2_RAT", "id": "Q499N4-1", "name": "4-hydroxybenzoate polyprenyltransferase, mitochondrial", "aln": "-------MLRLGGAGLVRG-LRVVSPAWLRGPGGLPLALARTTGTSGARDRRAPASGTQRGRALSLS-AAAVVNSAPRPLQPYLRLMRLDKPIGTWLLYLPCTWSIGLAADPG---CFPDWYMLSLFGTGAILMRGAGCTINDMWDRDFDKKVERTANRPIAAGDISAFQSFVFLGAQLTLALGVLLHLNYYSIAMGAASLLLVVTYPLMKRVTFWPQLALGLTFNWGALLGWSAVKGSCDPAVCLPLYFSGVMWTLIYDTIYAHQDKKDDALIGLKSTALLFRENTKQWLSGFGVAMVGALSLVGASSGQTLP--YYAAVAAVGAHLAHQIYTVDIHRAEDCWEKFTSNRTVGLLLFLGIVLGNLYKDKPDETKGVDAVGEESERTS------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q66JT7-1", "uniprot_id": "COQ2_MOUSE", "id": "Q66JT7-1", "name": "4-hydroxybenzoate polyprenyltransferase, mitochondrial", "aln": "-------MLRWGGAGLARG-LRAVRSAWLRGPRGLPLALVRSAGVPGARDRRAPAPGTQRGRALSLS-AAAVVNSAPRPLQPYLRLMRLDKPIGTWLLYLPCTWSIGLAADPG---CFPDWYMLSLFGTGAILMRGAGCTINDMWDRDFDKKVTRTANRPIAAGDISTFQSFVFLGGQLTLALGVLLCLNYYSIAMGAASLLLVVTYPLVKRITFWPQLALGLTFNWGALLGWSAVKGSCDPAVCLPLYFSGVMWTLIYDTIYAHQDKKDDALIGLKSTALLFQENTRQWLSGFGVAMVAALSLAGANNGQTVP--YYAAVAAVGAHLAHQIYTVDIHRAEDCWDKFTSNRTVGMLLFLGIVLGNLCKEKTEEAKDAEAVRVGSEQTS------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96H96-1", "uniprot_id": "COQ2_HUMAN", "id": "Q96H96-1", "name": "4-hydroxybenzoate polyprenyltransferase, mitochondrial", "aln": "-------MLGSRAAGFARG-LRAVALAWLPGWRGRSFALARAAGAPHGGDLQPPACPEPRGRQLSLS-AAAVVDSAPRPLQPYLRLMRLDKPIGTWLLYLPCTWSIGLAAEPG---CFPDWYMLSLFGTGAILMRGAGCTINDMWDQDYDKKVTRTANRPIAAGDISTFQSFVFLGGQLTLALGVLLCLNYYSIALGAGSLLLVITYPLMKRISYWPQLALGLTFNWGALLGWSAIKGSCDPSVCLPLYFSGVMWTLIYDTIYAHQDKRDDVLIGLKSTALRFGENTKPWLSGFSVAMLGALSLVGVNSGQTAP--YYAALGAVGAHLTHQIYTLDIHRPEDCWNKFISNRTLGLIVFLGIVLGNLWKEK-KTDKTKKGIENKIEN--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHS7-1", "uniprot_id": "COQ2_DROME", "id": "Q9VHS7-1", "name": "4-hydroxybenzoate polyprenyltransferase, mitochondrial", "aln": "--MYALRHLRLQSARHFRSSYAAAATTKHMLPRQPARVLIGDWSTWDKSRLQDVCSRSSSTATEPVK-QQTPLQELVSAAKPYAQLMRIDRPIGTYLLFWPCAWSIALSADAG---CWPDLTMLGLFGTGALIMRGAGCTINDLWDKDIDAKVERTRLRPLASGQISQFDAIVFLSAQLSLGLLVLVQLNWQSILLGASSLGLVITYPLMKRVTYWPQLVLGMAFNWGALLGWCATQGSVNLAACLPLYLSGVCWTIVYDTIYAHQDKLDDLQIGVKSTALRFGENTKVWLSGFTAAMLTGLSAAGWACDQTVP--YYAAVGVVGAHLVQQIYSLNIDNPSDCAKKFISNHQVGLILFLGIVLGTLLKSDESKKQRQSSLTTSTASSYVPALPQKPEVLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32378-1", "uniprot_id": "COQ2_YEAST", "id": "P32378-1", "name": "4-hydroxybenzoate polyprenyltransferase, mitochondrial", "aln": "MFIWQRKSILLGRSILGSGRVTVAGIIGSSRKRYTSSSSSSSSPSSKESAPVFTSKELEVARKERLDGLGPFVSRLPKKWIPYAELMRLEKPVGTWLLYLPCSWSILMGAMMQGATLSATAGMLGIFGVGALVMRGAGCTINDFLDRKLDQRVIRSVERPIASGRVSPRRALVFLGAQTLVGMGVLSLLPAQCWWLGLASLPIVFTYPLFKRFTYYPQAALSACFNWGALLGFPAMG-VMSWPTMIPLYLSSYLWCMTYDTIYAHQDKKFDIKAGIKSTALAWGPRTKSIMKAMSASQIALLAVAGLNSGLLWGPGFIGGLGVFAYRLFSMIKKVDLDNPKNCWKYFNANINTGLYFTYALAVDYILRLFGFL---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . .. . . :. . :. ** .***:::*:**:**: **:*** :.* . **.:**.**::**********: *:. * :* *: **:*:* :* ::***..* :.: ** * . :* .** :*.****.**.:::** .*. ********: * . .. :***:*. * : ********** * *:***** : .*: :..: .: : *: .* . : ..:.... :* * .:::....:* . * :* *: . .:.:. : : ", "identical_positions": 101, "similar_positions": 106, "identity": "25.25%" }, { "cls_id": "homologset.agr.SGD:S000005326", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99JF5-1", "uniprot_id": "MVD1_MOUSE", "id": "Q99JF5-1", "name": "Diphosphomevalonate decarboxylase", "aln": "MAS-EKPQDLMVTCTAPVNIAVIKYWGKRDEALILPINSSLSVTLHQDQLKTTTTVAISKDFTEDRIWLNGREEDVGQP-RLQACLREIRRLARKRRSTEDGDTLPLSLSYKVHVASVNNFPTAAGLASSAAGYACLAYTLAQVYGVEG---DLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQIAPEWHWPQLRILILVVSADKKQTGSTVGMQTSVETSTLLKFRAESVVPERMKEMTRCIQEQDFQGFAQLTMKDSNQFHATCLDTFPPISYLNDTSRRIIQLVHRFNTHQGQTKVAYTFDAGPNAVIFTLEDTVAEFVAAVRHSFP-PAANGDKFLKGLQVAPVLLSDEL---KAALAVEPSPGGVQYIIATQVGPGPQVLDDTHDHLLGQDGLPQRDL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62967-1", "uniprot_id": "MVD1_RAT", "id": "Q62967-1", "name": "Diphosphomevalonate decarboxylase", "aln": "MAS-EKPQDLMVTCTAPVNIAVIKYWGKRDEALILPINSSLSVTLHQDQLKTTTTAAISKDFTEDRIWLNGREEDVGQP-RLQACLREIRRLARKRRSTGDGDALPLSLGYKVHVASVNNFPTAAGLASSAAGYACLAYTLARVYGVEG---DLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQIAPEWHWPQLRVLILVVSAEKKPTGSTVGMQTSVATSTLLKFRAESIVPERMKEMTRCIQEQDFQAFAQLTMKDSNQFHATCLDTFPPISYLNDTSRRIIQLVHRFNAHHGQTKVAYTFDAGPNAVIFTLEDTVAEFVAAVRHSFP-PAANGDKFLKGLQVAPVLLSDEL---KTSLATEPSPGGVQYIIATQVGPGPQVLDDPHHHLLGPDGLPQRDL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53602-1", "uniprot_id": "MVD1_HUMAN", "id": "P53602-1", "name": "Diphosphomevalonate decarboxylase", "aln": "MAS-EKP-LAAVTCTAPVNIAVIKYWGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDFTEDRIWLNGREEDVGQP-RLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPTAAGLASSAAGYACLAYTLARVYGVES---DLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQVAPESHWPELRVLILVVSAEKKLTGSTVGMRASVETSPLLRFRAESVVPARMAEMARCIRERDFPSFAQLTMKDSNQFHATCLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKVAYTFDAGPNAVIFTLDDTVAEFVAAVWHGFP-PGSNGDTFLKGLQVRPAPLSAEL---QAALAMEPTPGGVKYIIVTQVGPGPQILDDPCAHLLGPDGLPKPAA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5U403-1", "uniprot_id": "MVD1_DANRE", "id": "Q5U403-1", "name": "Diphosphomevalonate decarboxylase", "aln": "MSENILQDLEMVTCTAPVNIAVIKYWGKRDEDLILPVNASLSVTLHQDHLRTTTTIACSRSFHKDCIWLNGKEQDISHP-RLQSCLLEIRRLAQRRKNTGDP---ASDVSNKVHICSVNNFPTAAGLASSAAGYACLVYTLSQLFNVEG---ELSGVARQGSGSACRSLYGGFVQWKLGEQSDGKDSIAEQVASELYWPELRVLILVVSAEQKSVGSTSGMHTSVETSHLLKYRADAVVPGRMEEMIRAIRLRDFPKFGELTMKDSNQFHAICLDTYPPIFYLNNISHQIISLVHRYNQYYGETRVAYTFDAGPNAVIYSLQDYLPEFVEVVRHFFP-PEVNEEEFFKGLPVCPADLSEEM---IRDINMKPTPNGIRYMISTKAGPGPRVVEDPNLHLLGADGLPKKSAV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXQ3-1", "uniprot_id": "Q9VXQ3_DROME", "id": "Q9VXQ3-1", "name": "Diphosphomevalonate decarboxylase", "aln": "MFS--------VTCVAPVNIALIKYWGKRHEELILPVNDSISMTLSTDELCAKTTVTASESFETNRMWLNGEEVPFEESSRLQRCLNEVHRLAVASGSQKVP------PTWKLHIASVNNFPTAAGLASSAAGYACLVYSLSRLYDIPLNE-ELTTVARQGSGSACRSLYGGFVQWHRGALDDGSDSVARQIAPSDHWPNMHVLILVVNDARKKTASTRGMQQAVKTSQLIKHRVDQVVPDRIIRLREAIASHDFQAFAEITMKDSNQFHAIALDTYPPCVYMNDVSHSIVSFVHDYNERMGSYHAAYTFDAGPNACLYVLAEHVPHLLSAIQKVFPNDLADGGTYLRGLPIPKVQDAESS---KLDSLDVHAKNAFRYIIHTKVGEGPKELSADNSLLIN--GLPLK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32377-1", "uniprot_id": "MVD1_YEAST", "id": "P32377-1", "name": "Diphosphomevalonate decarboxylase", "aln": "MTV------YTASVTAPVNIATLKYWGKRDTKLNLPTNSSISVTLSQDDLRTLTSAATAPEFERDTLWLNGEPHSIDNE-RTQNCLRDLRQLRKEMESKDAS--LPTLSQWKLHIVSENNFPTAAGLASSAAGFAALVSAIAKLYQLPQSTSEISRIARKGSGSACRSLFGGYVAWEMGKAEDGHDSMAVQIADSSDWPQMKACVLVVSDIKKDVSSTQGMQLTVATSELFKERIEHVVPKRFEVMRKAIVEKDFATFAKETMMDSNSFHATCLDSFPPIFYMNDTSKRIISWCHTINQFYGETIVAYTFDAGPNAVLYYLAENESKLFAFIYKLFG-SVPGWDKKFTTEQLEAFNHQFESSNFTARELDLELQKDVARVILTQVGSGPQ--ETNESLIDAKTGLPKE---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .: .****** :******. * ** * *:*:** *.* : *: . : .* : :****. . . * * ** ::: * . *:*: * ***************:*.*. :::::: : ::: :**:*********:**:* *. * ** **:* *:* . **::: :***. :* ..** **: :* ** *:: * : :** *: : ..* :** *.: ** ***.*** .**::** *:* * *: * * *. .********** :: * : ..:. : : * . : : . . :* *:.* **: . : *** ", "identical_positions": 138, "similar_positions": 94, "identity": "33.58%" }, { "cls_id": "homologset.agr.SGD:S000005329", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UI30-1", "uniprot_id": "TR112_HUMAN", "id": "Q9UI30-1", "name": "Multifunctional methyltransferase subunit TRM112-like protein", "aln": "MKLLTHNLLSS--HVRGVGSRGFPLRLQATEVRICP---VEFNPNFVARMIPKVEWSAFLEAADNLRLIQ-VPKGP------VEGYEENEEFLRTMHHLLLEVEVIEGTLQCPESGRMFPISRGIPNMLLSEEETES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DCG9-1", "uniprot_id": "TR112_MOUSE", "id": "Q9DCG9-1", "name": "Multifunctional methyltransferase subunit TRM112-like protein", "aln": "MKLLTHNLLSS--HVRGVGTRGFPLRLQATEVRINP---VEFNPEFVARMIPKVEWAALVQAADTLNLAE-VPKEP------TEGYEHDETFLRKMHHVLLEVDVLEGTLQCPESGRLFPISRGIPNMLLNDEETET", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VP65-1", "uniprot_id": "TR112_DROME", "id": "Q9VP65-1", "name": "Multifunctional methyltransferase subunit TRM112-like protein", "aln": "MKLSTYNFLTSV-AIKGVK-VGFPLKLTINKKEVVE---SEFNPTFVERILPKLDWSAVYGAAQVAELTEDIPAVQ------PENIVENELLLQKLHHLLFEIDVLEGQLECPETGRVFPISDGIPNMLLNEDEV--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53738-1", "uniprot_id": "TR112_YEAST", "id": "P53738-1", "name": "Multifunctional methyltransferase subunit TRM112", "aln": "MKFLTTNFLKCSVKACDTSNDNFPLQYDGSKCQLVQDESIEFNPEFLLNIVDRVDWPAVLTVAAELGNNALPPTKPSFPSSIQELTDDDMAILNDLHTLLLQTSIAEGEMKCRNCGHIYYIKNGIPNLLLPPHLV--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: * *:*.. .. .***: .: .: **** *: .:: :::*.*. .* * * .: :*. :* :*:: .: ** ::* : *::: *. ****:** . . ", "identical_positions": 32, "similar_positions": 42, "identity": "23.36%" }, { "cls_id": "homologset.agr.SGD:S000005331", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAH8-1", "uniprot_id": "D4AAH8_RAT", "id": "D4AAH8-1", "name": "Cell cycle control protein", "aln": "----MEMVPQ---------------YDLSRLPENTALKQQTLPAQQLNLSASIVLSIFFATGGFCLSVGVILLLFAKSTKEIEINYTN--MCANCAQLREDS----------------------SNFDKECNCSLPLYLPEKMEGDVYMYYKLYGFYQNLYRYILSRSNSQLVG-KDIWDTTN--CSPFQVSK-NDTPIIPCGAIANSIFNDTITLSYNLNSS--TQIEVPMLRSGLTWWTDKYVKFRNPRTSN---FTSTFAGSSKPLHWAKPVYELDLEDPGNNGFVNEDFIVWMRTAAFPTFRKLYRRLRREDS-FADGLPAGNYSLSISYNFPVTMFQGEKSVILSTLTWFGGGGLFLGLTYTVTGALTLLASFAILAVHLKLKRNKLSFL-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D4D7-1", "uniprot_id": "CC50C_MOUSE", "id": "Q9D4D7-1", "name": "Cell cycle control protein 50C", "aln": "----MEMMPQ---------------YDLSRLPENTALKQQTLPTQQLNLSASVVLSIFFITGGFCLSIGIILLLSAKSTKKIEINYTK--TCANCAQLRENS----------------------SNFDKACNCSLPFYLPEKMEGDVYMYYKLYGFYQNLYQYILSRSNSQLVG-KDIWDTTN--CDPFQVSH-NDTPIIPCGAIANSIFNDTITLSYNLNSS--TQIEVPMLKSGLTWWTDKYVKFRNPRSSN---FTSTFAGSSKPLHWAKPIYELDLDDPGNNGFLNEDFIVWMRTAAFPTFKKLYRRLKRVHA-FAEGLPAGNYSLSISYNFPVTMFQGEKSIVLSTLTWIGGGGLFLGLTYTVTGALTLLASFAILTIHLMLKRSKLNFL-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PHF1-1", "uniprot_id": "A0A8M1PHF1_DANRE", "id": "A0A8M1PHF1-1", "name": "Cell cycle control protein", "aln": "--MAKKAVGL---------------GPLSRRPDNSAFKQQRLPAWSPSLTAQTVLPIFYILAVVCLLLGIWLLITVQNTHQLKVDYTDAGTCERCFELHAN------------------------NTRTVCTCSVNFYVPRPFPGDVFFYYGLRNFHQNLRRYMDSRDDAQMVGRKNNLKAPSSYCAPFHYDA-NGVPIAPCGAVANSMFNDSFTLMYHQANG--AEVQVPLYRKGIAWYTDKNVKFRNPPTNNTFSLRQAFEGTTRPLYWQHSVYELDDTDSNNNGFINDDLIVWMREAAFPNFKKLYGVLNRAQEPFTEGLPAGNYNISIDYNFPVEPFRGRKELVISMVTWFGGQNYFLPIAYLVTSGLILVTAVVLTTVFVKFGKNGKNMEE------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BHG3-1", "uniprot_id": "CC50B_MOUSE", "id": "Q8BHG3-1", "name": "Cell cycle control protein 50B", "aln": "----MTWSAT---------------ARGAHQPDNTAFTQQRLPAWQPLLSAGIALPLFFCAGLAFIGLGLGLFYSSNGIKELEYDYTGNPGTGDCSVCAAKG--------------------QGRAPPPGCACSWSFTLPELFPGPVYLYYELSNFYQNNRRYGVSRDDAQLSGLASALRHPANECAPYQFRS-DGLPIAPCGAIANSLFNDSFSLWHQRQPSD-PFVEVPLDRTAIAWWTDYHVKFRNPPLVNG-SLALAFRGTAPPPNWHRPVYELSPDPN-NTGFINQDFVVWMRTAALPTFRKLYARIRQ--GNYSAGLPRGTYRVNITYNYPVRAFGGHKLIILSNISWMGGKNPFLGIAYLVVGSLCIVMGFVMLVVYIRYQDQDDDDNDDE----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z9E9-1", "uniprot_id": "D3Z9E9_RAT", "id": "D3Z9E9-1", "name": "Cell cycle control protein", "aln": "----MTWSAS---------------ARGAQQPDNTAFTQQRLPAWQPLLSAGITLPLFFCAGLAFIGLGLGLFYSSNGIQELEYDYTGNPGTGNCSVCAAKG--------------------QDRAPPPSCQCSWSFTLPELFPGPVYLYYELSNFYQNNRRYGVSRDDAQLSGLASALRHPANECAPYQFSS-DGLPIAPCGAIANSLFNDSFSLWHQRQPAD-PFVEVPLDRTAIAWWTDYHVKFRNPPLVNG-SLALAFKGTAPPPNWHRPVYELSPDPN-NTGFINQDFVVWMRTAALPTFRKLYARIRQ--GNYSAGLPRGTYRVNITYNYPVRAFGGHKLIILSNISWMGGKNPFLGIAYLVVGSLCILMGFVMLVVYIRYQDQDDDDNDDE----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3MIR4-1", "uniprot_id": "CC50B_HUMAN", "id": "Q3MIR4-1", "name": "Cell cycle control protein 50B", "aln": "----MTWSAT---------------ARGAHQPDNTAFTQQRLPAWQPLLSASIALPLFFCAGLAFIGLGLGLYYSSNGIKELEYDYTGDPGTGNCSVCAAAG--------------------QGRALPPPCSCAWYFSLPELFQGPVYLYYELTNFYQNNRRYGVSRDDAQLSGLPSALRHPVNECAPYQRSA-AGLPIAPCGAIANSLFNDSFSLWHQRQPGG-PYVEVPLDRSGIAWWTDYHVKFRNPPLVNG-SLALAFQGTAPPPNWRRPVYELSPDPN-NTGFINQDFVVWMRTAALPTFRKLYARIRQ--GNYSAGLPRGAYRVNITYNYPVRAFGGHKLLIFSSISWMGGKNPFLGIAYLVVGSLCILTGFVMLVVYIRYQDQDDDDEE------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VEK0-1", "uniprot_id": "CC50A_MOUSE", "id": "Q8VEK0-1", "name": "Cell cycle control protein 50A", "aln": "--MAMNYSAKDEVD--GGPAGPPGGAAKTRRPDNTAFKQQRLPAWQPILTAGTVLPTFFIIGLIFIPIGIGIFVTSNNIREIEIDYTGTEPSSPCNKCLS-------------------------PNVTSCACTINFTLKQSFEGNVFMYYGLSNFYQNHRRYVKSRDDSQLNGDPSALLNPSKECEPYRRN--EDRPIAPCGAIANSMFNDTLELYLVANESDPKPIPIPLKKKGIAWWTDKNVKFRNPPGKE--SLEEKFKDTIKPVNWHKAVYELDPEDESNNGFINEDFIVWMRTAALPTFRKLYRLIERR-DDLHPTLPAGQYFLNITYNYPVHSFDGRKRMILSTISWMGGKNPFLGIAYITIGSISFLLGVVLLVINHKYRNSSNTADITI----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AY41-1", "uniprot_id": "CC50A_RAT", "id": "Q6AY41-1", "name": "Cell cycle control protein 50A", "aln": "--MAMNYSAKDEVD--GGPTGPPGGAAKTRRPDNTAFKQQRLPAWQPILTAGTVLPTFFIIGLIFIPIGIGIFVTSNNIREIE-------------------------------------------------------------GNVFMYYGLSNFYQNHRRYVKSRDDSQLNGDPSALLNPSKECEPYRRN--EDKPIAPCGAIANSMFNDTLELFLVANESDPKPVPILLKKKGIAWWTDKNVKFRNPPGKD--SLQEKFKDTTKPVNWHKPVYELDPDDESNNGFINEDFIVWMRTAALPTFRKLYRLIERT-DDLHPTLPAGQYYLNITYNYPVHFFDGRKRMILSTISWMGGKNPFLGIAYITIGSISFLLGVVLLVINHKYRNSSNTADITI----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NV96-1", "uniprot_id": "CC50A_HUMAN", "id": "Q9NV96-1", "name": "Cell cycle control protein 50A", "aln": "--MAMNYNAKDEVD--GGPPCAPGGTAKTRRPDNTAFKQQRLPAWQPILTAGTVLPIFFIIGLIFIPIGIGIFVTSNNIREIEIDYTGTEPSSPCNKCLS-------------------------PDVTPCFCTINFTLEKSFEGNVFMYYGLSNFYQNHRRYVKSRDDSQLNGDSSALLNPSKECEPYRRN--EDKPIAPCGAIANSMFNDTLELFLIGNDS--YPIPIALKKKGIAWWTDKNVKFRNPPGGD--NLEERFKGTTKPVNWLKPVYMLDSDPD-NNGFINEDFIVWMRTAALPTFRKLYRLIERK-SDLHPTLPAGRYSLNVTYNYPVHYFDGRKRMILSTISWMGGKNPFLGIAYIAVGSISFLLGVVLLVINHKYRNSSNTADITI----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PEQ2-1", "uniprot_id": "A0A8M1PEQ2_DANRE", "id": "A0A8M1PEQ2-1", "name": "Cell cycle control protein", "aln": "-MMASSYNAKEEDGHHSGTAGLGGTAIRTRKPDNTAFKQQRLPAWQPILTAGTVLPAFFVIGLIFIPIGIGLYVTSNNIKEFEIDYTGTDMSSPCFNCSQS---------------------FSWNSTTPCKCTLSFSLDQPFESNVFMYYGLSNFYQNHRRYVKSRDDSQLNGDERSLKEPSKECEPYRIN--DNKRIAPCGAIANSMFNDTLDLFYIDPNG--TKTQIPMIKKGIAWWTDKHVKFRNPGGNNP-NLTAVFIDTAKPINWRKPVYELDTDPE-NNGFINEDFIVWMRTAALPTFRKLYRIIQKK-NNMTPTLPRGNYSLEVTYNYPVRSFEGRKRMILSTISWMGGKNPFLGIAYITVGSICFFLGVVLLFIHHKYGNRNNSSDIPS----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXG0-1", "uniprot_id": "Q9VXG0_DROME", "id": "Q9VXG0-1", "name": "", "aln": "---MSTQQAENEES----------AAAKSKRPSDSAFKQQRLPAWQPVLTARTVLPTFFVIGVLFIPIGVVLLHLSNTANELIIDYTKCRRSGGNTTCAEY---------------------LEANPGVTCPCEVPFVLPSDFNGVVYMYYGLTNYYQNHRRYVKSRDDEQLLGHLS--QTPSTDCAPFAYDPDSGKPIAPCGAIANSLFNDTLTLLQ-------GGSEIKLLKTGIAWPSDKRVKFRNP---EG-NLNVSLEGFSKPIFWQKGLADLDPENPDNNGFQNEDLIVWMRTAALPSFRKLYRRLNQTNTNYANGLKSGNYTLNIKYNYPVVSFDGTKRMILSTTSVLGGKNPFLGIAYIVVGAICITLGLALLFIHMRCSRSNMEMINVNPHTQYS----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53740-1", "uniprot_id": "YN8S_YEAST", "id": "P53740-1", "name": "Phospholipid-transporting ATPase accessory subunit CRF1", "aln": "MGLILRWKEKKQLS-------SKQNAQKSRKPANTSFRQQRLKAWQPILSPQSVLPLLILMACVFAPIGIGLVVSTISVQRLVVNYTECDALAPAKHFETIPSEYVDYHFSKKVAVQPQWMVLTDPELGNQTCRIQFEVPNHIKKSTYVYYRLTNFNQNYREYVQSLDLDQLKGKALIGNDLDPNCDPLRTVE--NKTIFPCGLIANSMFNDTFGTTLTGVNDT---ADYLLTTKGIAWDTDSHRYGKTEYNAS---------DIVPPPNWAKLFPNGYTDDNIPDLQNWEQFKIWMRTAALPNFYKLAMKNETN------GLGKGIYIADIELNYPVRSFYGTKSFVLTTNSIIGAGNEALGIVYLIVAGIATLFAILFLIKVIFKPRPMHDHSYLNFENSDTPFDESSVVSIPLREIL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * :::: ** * : . *:. .*. : . :*: : ..: .:.** * .: ** .* * . *: * * * . * *** :***:***:: : ..::* :* :. . . * * : . ::: :*** **:*.* ** . * * * .: *:** * * * .::: : :*. . * :.* ..: .. : ", "identical_positions": 53, "similar_positions": 71, "identity": "12.62%" }, { "cls_id": "homologset.agr.SGD:S000005333", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2VCW9-1", "uniprot_id": "AASS_RAT", "id": "A2VCW9-1", "name": "Alpha-aminoadipic semialdehyde synthase, mitochondrial", "aln": "MLRAQRLRLARLRACVSRG-------LHHKPVMALRREDVNAWERRAPLAPKHIKGITKLGYKVLIQPSNRRAIHDKEYVRAGGILQEDITEACLILGVKRPPEEKLMSKKTYAFFSHTIKAQEANMSLLDEVLKQEIRLIDYEKMVDHRGSRIVAFGHWAGVAGMINILHGMGLRLLALGHHTPFMHLGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQEVFNELPCEYVEPHELKEVSKTGDLRKVYGTVLSRHHHLVRKTDGVYDPVEYEKYPERYISRFNADIAPYTTCLINGIYWEQNTPRLLTRQDAQSLLVPVKSSVVPVEG-CPELPHKLVAICDISADTGGSIDFMTECTTIERPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIEATEYFGDMLYPYVEEMLLSDASQPLESQNFSPVVRDAVITSNGLLTDKYKYIQKLRESRERIQFLSMS----TKKKVLVLGSGYVSGPVLEYLSRGNNIEITLGSDMTNQMQQLSKKY-DINTVNVTVGKQEDKLQSLVESQDLVISLLPYVLHPVVAKACIDSKVNMVTASYITPAMKELEKSVDDAGITVIGELGLDPGLDHMLAMETIDKAKDLGATIESYVSYCGGLPAPEHSDNPLRYKFSWSPVGVLMNIMQPASYLLNGKVVNVTGGVSFLNSVTPMDYFPGLNLEGYPNRDSTKYAEIYGIS-SAHTLLRGTLRYKGYSKALNGFVKLGLINRETYPALRPEANPLTWKQLLCDLVGISRSSSCEKLKEVVFTKLGGDSTQ----LEAAEWLGLLGDEQVPQAESIVDAFSKHLVSKLSYGPEEKDMIVMRDSFGIRHPSGHLENKTIDLVVYGDFNGFSAMAKTVGLPTAMAAKMLLDGEIETKGLMGPFSKEIYGPILERIKAEGIVFNTQSTIKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99K67-1", "uniprot_id": "AASS_MOUSE", "id": "Q99K67-1", "name": "Alpha-aminoadipic semialdehyde synthase, mitochondrial", "aln": "MLRAQRPRLARLRACLSRG-------LHHKPVMALRREDVNAWERRAPLAPKHIKGITKLGYKVLIQPSNRRAIHDKEYVRAGGILQEDITEACLILGVKRPPEEKLMSKKTYAFFSHTIKAQEANMNLLDEVLKQEIRLIDYEKMVDHRGSRIVAFGQWAGVAGMINILHGMGLRLLALGHHTPFMHLGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQEVFNELPCEYVEPHELREVSKTGDLRKVYGTVLSRHHHLVRKTDGVYDPVEYEKYPERYTSRFNTDIAPYTTCLINGIYWEQNTPRLLTRQDAQSLLVPVKSSVVPVEG-CPELPHKLVAICDISADTGGSIDFMTECTTIERPFCMYDADQQIIHDSVEGSGILMCSIDNLPAQLPIEATEYFGDMLYPYVEEMLLSDASQPLESQNFSPVVRDAVITSNGLLTDKYKYIQKLRESRERIQFLSMS----TKKKVLVLGSGYVSGPVLEYLSRDNNIEITLGSDMTNQMQQLSKKY-NINPVSLTVGKQEAKLQSLVESQDLVISLLPYVLHPVVAKACIESRVNMVTASYITPAMKELEKSVDDAGITVIGELGLDPGLDHMLAMETIDTAKELGATVESYVSYCGGLPAPEHSDNPLRYKFSWSPVGVLMNIMQPASYLLNGKVVNVTGGVSFLNSVTPMDYFPGLNLEGYPNRDSIKYAEIYGIS-SAHTLLRGTLRYKGYSKALNGFVKLGLINREAYPALRPEANPLTWKQLLCDLVGISRSSPCEKLKEVVFTKLGGDNTQ----LEAAEWLGLLGDEQVPQAESIVDAFSKHLVSKLSYGPEEKDMIVMRDSFGIRHPSGHLENKTIDLVVYGDFNGFSAMAKTVGLPTAMAAKMLLDGEIEAKGLMGPFTKEIYGPILERIKAEGIVFNTQSTIKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UDR5-1", "uniprot_id": "AASS_HUMAN", "id": "Q9UDR5-1", "name": "Alpha-aminoadipic semialdehyde synthase, mitochondrial", "aln": "MLQVHRTGLGRLGVSLSKG-------LHHKAVLAVRREDVNAWERRAPLAPKHIKGITNLGYKVLIQPSNRRAIHDKDYVKAGGILQEDISEACLILGVKRPPEEKLMSRKTYAFFSHTIKAQEANMGLLDEILKQEIRLIDYEKMVDHRGVRVVAFGQWAGVAGMINILHGMGLRLLALGHHTPFMHIGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQAIFNELPCEYVEPHELKEVSQTGDLRKVYGTVLSRHHHLVRKTDAVYDPAEYDKHPERYISRFNTDIAPYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGKFSPAGVEG-CPALPHKLVAICDISADTGGSIEFMTECTTIEHPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIEATECFGDMLYPYVEEMILSDATQPLESQNFSPVVRDAVITSNGTLPDKYKYIQTLRESRERAQSLSMG----TRRKVLVLGSGYISEPVLEYLSRDGNIEITVGSDMKNQIEQLGKKY-NINPVSMDICKQEEKLGFLVAKQDLVISLLPYVLHPLVAKACITNKVNMVTASYITPALKELEKSVEDAGITIIGELGLDPGLDHMLAMETIDKAKEVGATIESYISYCGGLPAPEHSNNPLRYKFSWSPVGVLMNVMQSATYLLDGKVVNVAGGISFLDAVTSMDFFPGLNLEGYPNRDSTKYAEIYGIS-SAHTLLRGTLRYKGYMKALNGFVKLGLINREALPAFRPEANPLTWKQLLCDLVGISPSSEHDVLKEAVLKKLGGDNTQ----LEAAEWLGLLGDEQVPQAESILDALSKHLVMKLSYGPEEKDMIVMRDSFGIRHPSGHLEHKTIDLVAYGDINGFSAMAKTVGLPTAMAAKMLLDGEIGAKGLMGPFSKEIYGPILERIKAEGIIYTTQSTIKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FD66-1", "uniprot_id": "E7FD66_DANRE", "id": "E7FD66-1", "name": "Alpha-aminoadipic semialdehyde synthase, mitochondrial", "aln": "MLRLVRSQGRGFRGCMCCQRRSQHNQQNHKSVIAIRREDVNVWERRAPLAPRHVREITAAGHKVLVQPSNRRAIHDRYYEKAGAVIQEDISEASLIIGVKRPPEEKVYPRKTYAFFSHTIKAQEANMGLLDDLLKKEVRLIDYEKMVDPNGYRIVAFGQWAGVAGMINILHGLGLRFLALGHHTPFMHIGMAHNYRNVSQAIQAVRDCGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQDIFNELPCEFVEPHELKEVSLSGDLTKVYATVISRHHHLMRRSDGLYDPLEYENHPELYTSHFRDTVAPYTTCLINGIYWDPHTPRLLRRLDAQRLIRPVVTTSSSADYGCPALPHKFLAICDISADTGGSIEFMTECTTIEKPFCMYDANQHIDHDSVEGNGILMCSIDNLPAQLPIEATEYFGDRLFPYVMEMLPSDATKPLEEEDFSPQVRDAVITSNGKLTPKFEYIQKLRERRESEQILKKG----GMKRVLLLGAGYVSGPVIEYLTRDAGTQVTVASNLLNQAEEMATRYPNTIAVMLDITSQEGHLESLIKDHDIVISMLPYSFHPQVAKHCIKLKVNMVTASYLSPAMKELQKSAEDAGITIVNEMGLDPGIDHMLAMECIDQAKADGCTVESYSSFCGGLPAPECSDNPLRYKFSWSPYGVLLNTISPAIYLKDNQIVSVPPGGALLDVTKEMDFMPGFNLEGFPNRDSTKYAEPYGIE-SAHTLIRGTLRFRGFSSAMSGFVKLGLINTEPCPLLDHTASPVSWKELLCKQIGLSATVSNSVFEDAVYEKIGKDDFR----MQSLKWLGLLGEEPVPHAETILAAVAKHLEAKLSFDKGERDMIIMRNDVGIRHPTGELETKHISLVVYGDPSGYSAMAKTVGYPAAIAAHMVLNGELTTKGLVVPMVKSIYSPVLKRLQDEGLQFITKSSVSE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLX0-1", "uniprot_id": "Q9VLX0_DROME", "id": "Q9VLX0-1", "name": "Alpha-aminoadipic semialdehyde synthase, mitochondrial", "aln": "MWRVIQLR-ATIAHPFTRQ--------RHSRVIAIRREDQSVWERRAPFGPTHVQKLVKQNVKVIVQPSNRRAYPMQAYMQAGAHIQEDISDASVIFGVKQVPIDALIPGKTYCFFSHTIKAQESNMPLLDAILEKKIRLIDYERIIDERGARQVAFGKYAGVAGMVNILHGIGLRLLALGHHTPFMHIGPAHNYRNSSMARQAIRDCGYEISLGMMPKSIGPLTFVFTGSGNVSQGAQEVFSELPIEYVPPEMLRKVAEHGNQNKLYGCEVSRSDHLERREGGGFDAKEYDEFPERYISTFSTKIAPYASVIVNGIYWAVGSPKLISIPDAKNLLRPANTPWLPTSKGSPALPHRMLAICDISADPGGSIEFMNECTTIDTPFCLYDADRNKDTKSFKGPGVLVCSIDNMPTQLPRESTDLFGELLAPHVHDIIKSDAKKPLAEENFSYPIQSAIIASNGQLTEGFQYIQELRESQSHRSRHKMEGSSESDKKVLVLGAGMVSAPLVEWLHREKDVSITVCSQVKEEADRLAQQYAGVDSVYLDVNESTGHLQELCGRADVVVSLLPYSLHGMVARYCVAEGTHMVTASYLNDEISGLHEEAKAKGVTIMNEVGLDPGIDHLLALECIHEVQDKGAVVESFVSYCGGLPAPEHSNNALRYKFSWSPRGVLLNTLSAAKYLSQGQIVEISGGGELMSSPRSLDFLPGFALEGFPNRDSTKYGNLYGLGRDVHTLLRGTIRYKGFSESIKPMQLLGLIDPEPHALLHPSGPDVTWRQLVIHLMGMSDS---TIFYENLKQKLTERIGD----VDGIESLGLLDDTPVVKLNTPLDTLSHYLSKRLAFERDERDLVVLRHEVGIRWPDGRREERGINFVVYGQPQGHSAMAMTVGKPAAIAAKMILDGEIQERGVLLPFTPDIYRPMLQRLRSEGLTATETSRWLN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38999-1", "uniprot_id": "LYS9_YEAST", "id": "P38999-1", "name": "Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MG------KNVLLLGSGFVAQPVIDTLAANDDINVTVACRTLANAQALAKPS-GSKAISLDVTDDS-ALDKVLADNDVVISLIPYTFHPNVVKSAIRTKTDVVTSSYISPALRELEPEIVKAGITVMNEIGLDPGIDHLYAVKTIDEVHRAGGKLKSFLSYCGGLPAPEDSDNPLGYKFSWSSRGVLLALRNSAKYWKDGKIETVSSE-DLMATAKPYFIYPGYAFVCYPNRDSTLFKDLYHIP-EAETVIRGTLRYQGFPEFVKALVDMGMLKDDANEIFS---KPIAWNEALKQYLGAKSTSKEDLIASIDSKATWKDDEDRERILSGFAWLGLFSDAKITPRGNALDTLCARLEELMQYEDNERDMVVLQHKFGIEWADGTTETRTSTLVDYGKVGGYSSMAATVGYPVAIATKFVLDGTIKGPGLLAPYSPEINDPIMKELKDKYGIYLKEKTVA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.**:**:* :: *::: * . .:*: . : : :. . .: : : .. * : *:*:*::** :* *.: .: ..:**:**:. : *. . *:*::.*:*****:**: *:: *. .: * ::*: *:******** *:*.* ******. ***: ..* * :.:: :. :: ** : :***** : : * : ...*::***:*::*: . :. : :*::. :. : ::*.: : . :* . : : . :.. ***:.: : . : :.. * : : *:*:::::...**. . * * : :* **. *.*:** *** *.*:*::::*:* : *:: * .* *:::.:: : . ", "identical_positions": 104, "similar_positions": 159, "identity": "11.02%" }, { "cls_id": "homologset.agr.SGD:S000005334", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYS7-1", "uniprot_id": "D3ZYS7_RAT", "id": "D3ZYS7-1", "name": "Ras GTPase-activating protein-binding protein 1", "aln": "-----------------MVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYAHGGLDSNGK-------PADAVYGQKEIHRKVMS--QNFTNCHTKIRHVDAHAT--LNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVFGGFVTEPQEESEEEVEEPE-ERQQSPEVVADDS-GTFYDQT-VSNDLEEHLEEPVVEPEPEPEPEPEPEPVSDIQEDKPEPA--LEEAAPEDVQKSA-SPAPADVAP-AQEDLRTFSWASVTSKNLPPSGAVPVTGTPPHVVKVPASQPRPESKPDSQIPPQRPQRDQRAREQRIN-IPPQRGPRP---------IREAGEPGDVEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQSYGNVVELRINS---GGKLPNFGFVVFDDSEPVQKVLNNR---PIMFRGAVRLNVEEKKTRAARE-------GDRRDNRL--RGPGGPRGGPSG-------GMRGPPRGGMVQKPGFGVGRGITT-------PRQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97855-1", "uniprot_id": "G3BP1_MOUSE", "id": "P97855-1", "name": "Ras GTPase-activating protein-binding protein 1", "aln": "-----------------MVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYAHGGLDSNGK-------PADAVYGQKEIHRKVMS--QNFTNCHTKIRHVDAHAT--LNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVFGGFVTEPQEESEEEVEEPE-ERQQTPEVVPDDS-GTFYDQT-VSNDLEEHLEEPVVEPEPEPEPEPEPEPVSDIQEDKPEAA--LEEAAPDDVQKST-SPAPADVAP-AQEDLRTFSWASVTSKNLPPSGAVPVTGTPPHVVKVPASQPRPESKPDSQIPPQRPQRDQRVREQRIN-IPPQRGPRP---------IREAGEPGDVEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQNFGNVVELRINS---GGKLPNFGFVVFDDSEPVQKVLSNR---PIMFRGAVRLNVEEKKTRAARE-------GDRRDNRL--RGPGGPRGGPSG-------GMRGPPRGGMVQKPGFGVGRGITT-------PRQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13283-1", "uniprot_id": "G3BP1_HUMAN", "id": "Q13283-1", "name": "Ras GTPase-activating protein-binding protein 1", "aln": "-----------------MVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGK-------PADAVYGQKEIHRKVMS--QNFTNCHTKIRHVDAHAT--LNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVFGGFVTEPQEESEEEVEEPE-ERQQTPEVVPDDS-GTFYDQAVVSNDMEEHLEEPVAEPEPDPEPEPEQEPVSEIQEEKPEPV--LEETAPEDAQKSS-SPAPADIAQTVQEDLRTFSWASVTSKNLPPSGAVPVTGIPPHVVKVPASQPRPESKPESQIPPQRPQRDQRVREQRIN-IPPQRGPRP---------IREAGEQGDIEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQSYGNVVELRINS---GGKLPNFGFVVFDDSEPVQKVLSNR---PIMFRGEVRLNVEEKKTRAARE-------GDRRDNRL--RGPGGPRGGLGG-------GMRGPPRGGMVQKPGFGVGRGLA--------PRQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BKD5-1", "uniprot_id": "A0A8M2BKD5_DANRE", "id": "A0A8M2BKD5-1", "name": "", "aln": "-----------------MVMEKPSAQLVGREFVRQYYTLLNQAPDYLHRFYGKNSSYVHGGLDNNGK-------PAEAVYGQSEIHKKVMA--LSFRDCHTKIRHVDAHAT--LNEGVVVQVLGELSNNMQPMRKFMQTFVLAPEGTVANKFYVHNDIFRYQDEVFGDSDSEPPEESEEDVEEL--ERVHSPEVVQEES-SGYYEQT-PCVEPEVPQEEVSVTPEPQPEPEVEVEPEPAAVELKAEPISQPEVHVEEKTQRSPPSPTPADTAPTMPEDNRPSSWASVTSKNLPPGGVVPATGVPPHVVRVPSAQPRVEVKTETQTTAQRPQRDQRPRDQRPGPSPAHRTPRPGGVQNSNELMVREGESGESEVRRTVRYPDSHQLFVGNVPHDVDKNELKEFFEQYGTVLELRINS---GGKLPNFGFVVFDDSEPVQKILNNR---PIKLRGDVRLNVEEKKTRSARE-------GDRRDIRP--RGPGGPRDRIGG-------SRGPPTRGGMAQKPSFGAGRGTGPSEGRYTGPRQ-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P97379-1", "uniprot_id": "G3BP2_MOUSE", "id": "P97379-1", "name": "Ras GTPase-activating protein-binding protein 2", "aln": "-----------------MVMEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGK-------PQEAVYGQNDIHHKVLS--LNFSECHTKIRHVDAHAT--LSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSVPNKFYVHNDMFRYEDEVFGDSEPELDEESEDEVEEEQEDRQPSPEPVQENANSAYYDAHPVTNGIEEPLEESSHEPEPEPESETKTEELKPQVEEK---------HLEELEEKSA-TPPPAEPASLPQEPPKAFSWASVTSKNLPPSGTVSSSGIPPH-VKAPVSQPRVDAKPEVQSQPPR-VREQRPRE-RPG--FPPRGPRP---------GRGDMEQNDSDNRRIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQRILIAK---PIMFRGEVRLNVEEKKTRAARERETRGGGDDRRDIRRNDRGPGGPRGIVGGGMMRDRDGRGPPPRGGMTQK--LGSGRGTGQMEGRFTGQRR-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L449-1", "uniprot_id": "A0ABK0L449_RAT", "id": "A0ABK0L449-1", "name": "Ras GTPase-activating protein-binding protein 2", "aln": "MLSLSSRRLHLTLCSKEMVMEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGK-------PQEAVYGQNDIHHKVLS--LNFSECHTKIRHVDAHAT--LSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSVPNKFYVHNDMFRYEDEVFGDSEPELDEESEDEVEEEQEDRQPSPEPVQENANSAYYEAHPVTNGIEEPLEESSHEPEPEPESETKTEELKPQAEEK---------HLEELEEKSA-TPPPTEPASLPQEPPKAFSWASVTSKNLPPSGTVSSSGIPPH-VKAPVSQPRVDAKPEVQSQPPR-VREQRPRE-RPG--FPPRGPRP---------GRGDTEQNDSDNRRIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQRILIAK---PIMFRGEVRLNVEEKKTRAARERETRGGGDDRRDIRRNDRGPGGPRGIVGGGMMRDRDGRGPPPRGGMTQK--LGSGRGTGQMEGRFTGQRR-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UN86-1", "uniprot_id": "G3BP2_HUMAN", "id": "Q9UN86-1", "name": "Ras GTPase-activating protein-binding protein 2", "aln": "-----------------MVMEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGK-------PQEAVYGQNDIHHKVLS--LNFSECHTKIRHVDAHAT--LSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSVPNKFYVHNDMFRYEDEVFGDSEPELDEESEDEVEEEQEERQPSPEPVQENANSGYYEAHPVTNGIEEPLEESSHEPEPEPESETKTEELKPQVEEK---------NLEELEEKST-TPPPAEPVSLPQEPPKAFSWASVTSKNLPPSGTVSSSGIPPH-VKAPVSQPRVEAKPEVQSQPPR-VREQRPRE-RPG--FPPRGPRP---------GRGDMEQNDSDNRRIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQRILIAK---PIMFRGEVRLNVEEKKTRAARERETRGGGDDRRDIRRNDRGPGGPRGIVGGGMMRDRDGRGPPPRGGMAQK--LGSGRGTGQMEGRFTGQRR-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53741-1", "uniprot_id": "BRE5_YEAST", "id": "P53741-1", "name": "UBP3-associated protein BRE5", "aln": "--------------------MGVTVQDICFAFLQNYYERMRTDPSKLAYFYASTAELTHTNYQSKSTNEKDDVLPTVKVTGRENINKFFSRNDAKVRSLKLKLDTIDFQYTGHLHKSILIMATGEMFWTGTPVYKFCQTFILLP-SSNGSTFDITNDIIRFISNSFKPYVLTDASLSQSNEENSVSAVEEDKIRHESGVEKEKEKEKSPEISKPKAKKETVKDTTAPTESSTQEKPIVDHSQPRAIPVT-KESKIHTETVPSSTKGNHKQDEVSTEELGNVTKLNEKSHKAEKKAAPIKTKEGSVEAINAVNNSSLPNGKEVSDEKPVPGGVKEAETEIKPIEPQVSDAKESGN-------NASTPSSSPEPVANPPKMTWASKLMNENSDRISKNNTTVEYIRPETLPKKPTERKFEMGNRRDNASANSKNKKKPVFSTVNKDGFYPIYIRGTNGLREEKLRSALEKEFGKVMRITAADNFAVVDFETQKSQIDALEKKKKSIDGIEVCLERKTVKKPTSNNPPGIFTNGTRSHRKQPLKRKD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *:::** :. *. * **. .:. .* . : ... * * *:.:*:: . .. . : *: :* : * * ..::: . * : . . :* ***:* * .: ..* : **::*: .: * . *:.: *: . . :* . . .*.. : : : : *. . : * . . . : * .. : . . . :.. .. : * : . .: : : .. . . . : . : :*: * : .:. ::: : .. *.: * . :..:** : ** :** *. *: :: :* : . .: . . .:* . * : ", "identical_positions": 51, "similar_positions": 138, "identity": "9.38%" }, { "cls_id": "homologset.agr.SGD:S000005335", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60809-1", "uniprot_id": "CNOT7_MOUSE", "id": "Q60809-1", "name": "CCR4-NOT transcription complex subunit 7", "aln": "-------------------------------------------------------------------------------------------------------MPAAT--VDHSQR-------------------------------------------ICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADYQYQLLRCNVDLLKIIQLGLTFMNEQGEYP-PGTSTWQFNFKFNLT-------------EDMYAQDSIELLTTSGIQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELDFFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFKMREMFFED---------------------HIDDAKYCGHLY-------------------GLGSGSS-------------YVQNGTGNAYEEEASKQS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABZ3NNN6-1", "uniprot_id": "A0ABZ3NNN6_RAT", "id": "A0ABZ3NNN6-1", "name": "poly(A)-specific ribonuclease", "aln": "-------------------------------------------------------------------------------------------------------MPAAT--VDHSQR-------------------------------------------ICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADYQYQLLRCNVDLLKIIQLGLTFMNEQGEYP-PGTSTWQFNFKFNLTSGTALGPGNPYFWEDMYAQDSIELLTTSGIQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELDFFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFKMREMFFED---------------------HIDDAKYCGHLY-------------------GLGSGSS-------------YVQNGTGNAYEEEASKQS----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UIV1-1", "uniprot_id": "CNOT7_HUMAN", "id": "Q9UIV1-1", "name": "CCR4-NOT transcription complex subunit 7", "aln": "-------------------------------------------------------------------------------------------------------MPAAT--VDHSQR-------------------------------------------ICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADYQYQLLRCNVDLLKIIQLGLTFMNEQGEYP-PGTSTWQFNFKFNLT-------------EDMYAQDSIELLTTSGIQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELDFFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFKMREMFFED---------------------HIDDAKYCGHLY-------------------GLGSGSS-------------YVQNGTGNAYEEEANKQS----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08BM8-1", "uniprot_id": "CNOT7_DANRE", "id": "Q08BM8-1", "name": "CCR4-NOT transcription complex subunit 7", "aln": "-------------------------------------------------------------------------------------------------------MPAAT--VDHSQR-------------------------------------------ICEVWACNLEEEMKRIRQVTRKFNYIAMDTEFPGVVARPIGEFRSNADYQYQLLRCNVDLLKIIQLGLTFMNEQGEYP-PGTSTWQFNFKFNLT-------------EDMYAQDSIELLTSSGIQFKKHEEEGIETMYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILSNSKLPDEEVDFFEILRLFFPIIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFKMREMFFED---------------------HIDDAKYCGHLY-------------------GLGSGSS-------------YVQNGTGNAYEEEANKQQS---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9D8X5-1", "uniprot_id": "CNOT8_MOUSE", "id": "Q9D8X5-1", "name": "CCR4-NOT transcription complex subunit 8", "aln": "-------------------------------------------------------------------------------------------------------MPAAL--VENSQV-------------------------------------------ICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDYQYQLLRCNVDLLKIIQLGLTFTNEKGEYP-SGINTWQFNFKFNLT-------------EDMYSQDSIDLLANSGLQFQKHEEEGIDTLHFAELLMTSGVVLCDNVKWLSFHSGYDFGYMVKLLTDSRLPEEEHEFFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFRMKELFFED---------------------SIDDAKYCGRLY-------------------GLGTGVA-------------QKQNEDVDCAQEKMSILAMINNMQQ---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UFF9-1", "uniprot_id": "CNOT8_HUMAN", "id": "Q9UFF9-1", "name": "CCR4-NOT transcription complex subunit 8", "aln": "-------------------------------------------------------------------------------------------------------MPAAL--VENSQV-------------------------------------------ICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDYQYQLLRCNVDLLKIIQLGLTFTNEKGEYP-SGINTWQFNFKFNLT-------------EDMYSQDSIDLLANSGLQFQKHEEEGIDTLHFAELLMTSGVVLCDNVKWLSFHSGYDFGYMVKLLTDSRLPEEEHEFFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFRMKELFFED---------------------SIDDAKYCGRLY-------------------GLGTGVA-------------QKQNEDVDSAQEKMSILAIINNMQQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X2JCC3-1", "uniprot_id": "X2JCC3_DROME", "id": "X2JCC3-1", "name": "poly(A)-specific ribonuclease", "aln": "---------------------------------------------------------------------------------------------------MKWTMPSAISGAPHAHIPSNEECG------------------------------------IRDVWKQNLEEEFRTIRKVVQKYHYVAMDTEFPGVVARPVGEFRSTADYHYQLLRCNVDLLRIIQLGLTFMDDDGKTP-PGYSTWQFNFKFNLS-------------EDMYAQDSIDLLQNSGIQFKKHEEDGIDPIDFAELLMSSGIVLVENIKWLCFHSGYDFGYLLKLLTDQNLPPDESEFFDLLHIYFPNIFDIKYLMKSCKNLKGGLQEVADQLELRRVGPQHQAGSDALLTGMAFFKMREVQHTNDFHITPVAHDVLFRYLLEHTMNLKPTISCIHLLSRPAYNGGPAPDESAIISSGNGTGNTNSTEQFTSSAYMVTPPNTPGMAKSDAASLSNRHTSISNSFG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39008-1", "uniprot_id": "POP2_YEAST", "id": "P39008-1", "name": "Poly(A) ribonuclease POP2", "aln": "MQSMNVQPRVLAVGGEQFFSQRQASEQHQQQNMGPQVYSPKVNRARMFPQGMPVNTINGSVNQEMNNAYLLKQKNEPLLTQQQQQQQQQQQPFNIGTPVSVASLPPGLNVLQQQQQQQQQQQQQQQGVGLNRPLASQLPKHLTNQSMPPIFLPPPNYLFVRDVWKSNLYSEFAVIRQLVSQYNHVSISTEFVGTLARPIGTFRSKVDYHYQTMRANVDFLNPIQLGLSLSDANGNKPDNGPSTWQFNFEFDPK-------------KEIMSTESLELLRKSGINFEKHENLGIDVFEFSQLLMDSGLMMDDSVTWITYHAAYDLGFLINILMNDSMPNNKEDFEWWVHQYMPNFYDLNLVYKIIQEFKNPQLQQSSQQQQQQQYSLTTLADELGLPRFSIFTTTGGQSLLMLLS-----------------FCQLSKLSMHKF-----------------------------------------PNGTDFAKYQGVIYGIDGDQ------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.. : : : :** ** .*: **:: .: ::::.*** *.:.**:* ***. **:** :*.***:*. *****:: : .*: * * .******:*: . ::: : :*::** .**::*:***: **: *::*** **::: :.:.*: :*:.**:*:::::* :. :* :: :* :. ::* ::*:: : * :::*. : :.* : .: ..: *. :::* . : . : * . : ", "identical_positions": 75, "similar_positions": 107, "identity": "14.71%" }, { "cls_id": "homologset.agr.SGD:S000005336", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7ENI9-1", "uniprot_id": "F7ENI9_RAT", "id": "F7ENI9-1", "name": "Nucleolar GTP-binding protein 2", "aln": "MVKPKYKGRSTINRSAASTNPDRVQGAGGQNMRDRGTIRRLNMYRQ-KERRNSRGKVIKPLQYQSTVAPGTVARVEPNIKWFGNTRVIKQASLQKFQEEMDKVMKDPYKVVMKQSKLPMSLLHDRVQPHNAKVHILDTESFESTFGPKSQRKRPNLFASDMQSLLENAEMSTESYDQGKDRDLVT--------EDTGVRNEAQEEIYKKGQSKRIWGELYKVIDSSDVVVQVLDARDPMGTRSSHIEAYLKKEKPWKHLIFVLNKCDLVPTWATKRWVAVLSKDYPTLAFHASLTNPFGKGAFIQLLRQFGKLHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPS-EDSETDIVLKGVVQVEKIKAPQDHIGAVLERAKPEYISKTYKIESWENAEDFLEKLALRTGKLLKGGEPDLLTVSKMVLNDWQRGRIPFFVKPPNAEMPTTPQLPPSSPLEVTTETTQNNPEEETIETEVERSDSVIEKEPEAGCSQDENSEMQQILARVRQNFGKINVGPQFSADDLVPVDDLVPVDLSDLED-LESSEEEEEQEQEQPGEDAEEECSRDTRGGPVEDDTKAVIRALDEKIAKYQRFLNKAKAKKFSAISCVILLLFFRISKDLSEKVFAKYEEEKKASAE-VSDAAPTKRARKWNAQVEEEP--SDKTQRMLTCKERRRAARQQQSKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHRHKKFRQKQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LH1-1", "uniprot_id": "NOG2_MOUSE", "id": "Q99LH1-1", "name": "Nucleolar GTP-binding protein 2", "aln": "MVKPKYKGRSTINRSAASTNPDRVQGAGGQNMRDRGTIRRLNMYRQ-KERRNSRGKVIKPLQYQSTVASGTVARVEPNIKWFGNTRVIKQASLQKFQEEMDKVMKDPYKVVMKQSKLPMSLLHDRIQPHNAKVHILDTESFESTFGPKSQRKRPNLFASDMQSLLENAEMSTESYDQGKDRDLVM--------EDTGVRNEAQEEIYKKGQSKRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHIEAYLKKEKPWKHLIFVLNKCDLVPTWATKRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQFGKLHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPS-EDSETDIVLKGVVQVEKIKAPQDHIGAVLERAKPEYISKTYKIESWENAEDFLEKLALRTGKLLKGGEPDMLTVSKMVLNDWQRGRIPFFVKPPNAELPTDSQLPPSSPLEVPTETTQNNPEEETTETEVERSDSITEKEPEGDCSQDRNSEMQQILARVRQNFGKINVGPQFSAD------DLVPVEMSDLED-LESSGEEEEQEQEQPGEDAEEERSPDTQEEPVGNDTKAVLRALDEKIAKYQRFLNKAKAKKFSAV---------RISKDLSEKVFAKYKEEKKTSAE-DSDAAPTKKARKWDAQMEEEP--SNKTQRMLTCKERRRAARQQQSKKVGVRYYETHNVKNRNRNKKKTSDSEGQKHRRNKFRQKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13823-1", "uniprot_id": "NOG2_HUMAN", "id": "Q13823-1", "name": "Nucleolar GTP-binding protein 2", "aln": "MVKPKYKGRSTINPSKASTNPDRVQGAGGQNMRDRATIRRLNMYRQ-KERRNSRGKIIKPLQYQSTVASGTVARVEPNIKWFGNTRVIKQSSLQKFQEEMDTVMKDPYKVVMKQSKLPMSLLHDRIRPHNLKVHILDTESFETTFGPKSQRKRPNLFASDMQSLIENAEMSTESYDQGKDRDLVT--------EDTGVRNEAQEEIYKKGQSKRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHIETYLKKEKPWKHLIFVLNKCDLVPTWATKRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQFGKLHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPS-EDSETDIVLKGVVQVEKIKSPEDHIGAVLERAKPEYISKTYKIDSWENAEDFLEKLAFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEPLVAPQLLPSSSLEVVPEAAQNNPGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKINVVPQFSGD------DLVPVEVSDLEEELESFSDEEEEEQEQQRDDAEES-SSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAKAKKFSAV---------RISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQKQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53742-1", "uniprot_id": "NOG2_YEAST", "id": "P53742-1", "name": "Nucleolar GTP-binding protein 2", "aln": "MGTGKKEKSRRIREGDTKDGNLRVKGE--NFYRDSKRVKFLNMYTSGKEIRNKKGNLIRAASFQDSTIP--DARVQPDRRWFGNTRVISQDALQHFRSALGETQKDTYQVLLRRNKLPMSLLEEKDADESPKARILDTESYADAFGPKAQRKRPRLAASNLEDLVKATNEDITKYEEKQVLDATLGLMGNQEDKENGWTSAAKEAIFSKGQSKRIWNELYKVIDSSDVVIHVLDARDPLGTRCKSVEEYMKKETPHKHLIYVLNKCDLVPTWVAAAWVKHLSKERPTLAFHASITNSFGKGSLIQLLRQFSQLHTDRKQISVGFIGYPNTGKSSIINTLRKKKVCQVAPIPGETKVWQYITLMKRIFLIDCPGIVPPSSKDSEEDILFRGVVRVEHVTHPEQYIPGVLKRCQVKHLERTYEISGWKDATEFIEILARKQGRLLKGGEPDESGVSKQILNDFNRGKIPWFVLPP-----------------------EKEGEEKPKKKEVEKTA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . * : *. . :. . **:* : ** :: **** . ** **.:*::*:. .:*.:. . ***:*: :********.* :**:*:. :. . **.*:*::::.*******.:: .. *.:******: :****:*****.* **:::.*:: :: . .*:: : * . ::.* . *:* *:.********.************::*******:***. :* *:***.* ****:***********.: ** **:: ********:**.****::*******.:****:************.****:*****.****:****.************:*********:* ** :*** **:::***:**::. *:::* .**:*.: :::.:**:*..*::* :*:* ** : *:******** *.* :***::**:**:** ** ::: *: :. * : ", "identical_positions": 253, "similar_positions": 143, "identity": "33.42%" }, { "cls_id": "homologset.agr.SGD:S000005337", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A8QI13-1", "uniprot_id": "A8QI13_DROME", "id": "A8QI13-1", "name": "Activator of basal transcription 1", "aln": "-----------------------MKEIKRKSKPKRKPTRMEVEEIET----SDKPQPEDGESANGEANPSDEGDEMELASFKAACSSSDPAKKI-----------------KKGIIYISNIPKHMTLTRLREILGEYGGIGRAFLRSQ-----------------SSKHHNILFAEGWVEFKSKHVAKQLVLLLNNKQISTRNNSPFYYSLWSMEYLPRFKWARLAELMNFVQVTNSQ---------------------NHLEFLKKKAKEAK----------------EVKKAMKVLADRLLELPLDSNI------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8QI32-1", "uniprot_id": "A8QI32_DROME", "id": "A8QI32-1", "name": "Activator of basal transcription 1", "aln": "-----------------------MKEIKRKSKPKRKPTRMEVEEIET----SDKPQPEDGESANGEANPSDEGDEMELASFKAACSSSDPAKKI-----------------KKGIIYISNIPKHMTLTHLREILGEYGGIGRAFLRSQ-----------------SSKHHNILFAEGWVEFKSKHVAKQLVLLLNNKQISTRNNSPFYYSLWSMEYLPRFKWARLAELMNFVQVTNSQ---------------------NHLEFLKKKAKEAK----------------EVKKAMKVLADRLLELALDSNI------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VY84-1", "uniprot_id": "Q9VY84_DROME", "id": "Q9VY84-1", "name": "Activator of basal transcription 1", "aln": "-----------------------MKEIKKKSKPKRKPTRMEVEESEPEMPFSYKTQPDEGESVNGEAHTSDDGDEMELATFKAAS--------------------------KKGVIYISNLPKHMTLTRLREILGEYGAIGRAFLRSQKL---------------SRKPHNFLFAEGWVEFKSKRVAKQIVPLLNYKQISTHKKSPFYYSLWIMEYLPRFKWARLNELMNIVPVTNSQ---------------------NHLKFLNKKAKKAK----------------KVKKAKKALADRLLELVLASSI------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W394-1", "uniprot_id": "Q9W394_DROME", "id": "Q9W394-1", "name": "Activator of basal transcription 1", "aln": "-----------------------MKNIKNKSKPKRKPTPMEVEEAELDEVRSDEPQPGEGETANGEANPSDDDDDMDLANFKATSSSSAPAKKR-----------------KMGIIYISNIPKHMNVTRLREILGEYGAIGRVYLQPEKLSSAKAK-------KNKRKRYNIHFTEGWVEFKSKRVAKQIVPLLNNKQISGRKTSQFYDSLWSMKYLPRFKWVHLTERMNYEQAVHKQRLHTEVSQ-----------ARKETTFFQNNLDKSE----------------FIRKQAKKAKNAEKALAAKSDSDA----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W393-1", "uniprot_id": "Q9W393_DROME", "id": "Q9W393-1", "name": "Activator of basal transcription 1", "aln": "---------------------------------------MKVEETKLDEARWGKPQTKEGESANGIANPSND-DKKELANFKATFNSWAPEKKREKM-------------HKVGVILISNIPKDMDGDCLKEIMNLHSVVGRVYVQPETL---------------SSFKTKKNMRKGWVEFISKSGAKKIALELNNKPITDGKSSRFRGLLWKMKFLPRFKWYYLTDRMDYELAVCKVRVWSQARKRA-----TFWYDPDQMEYFKKQVKKMKKMK-------------KVKEAEMATRNAEMAAKKAEMAAKKLKKSA----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IRM9-1", "uniprot_id": "Q8IRM9_DROME", "id": "Q8IRM9-1", "name": "Activator of basal transcription 1", "aln": "---------------------------------------MKVEETKLGEVRSGKPQTKEGESANGVANPSND-DKKELANFKATFNSWAPEKKREKM-------------HKVGVILISNIPKDMDGDCLKEIMNLHSVVGRVYVQPETL---------------SSFKTKKNMRKGWVEFISKSGAKKIALELNNKPITDGKSSRFRGLLWKMKFLPRFKWYYLTDRMDYELAVCKVRVWSQARKRA-----TFLYDPDQMEYFKKQVKKMK----------------KVKKAEMATRNAEMAAKKAEMAAKKLKKSA----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4KLM5-1", "uniprot_id": "ABT1_RAT", "id": "Q4KLM5-1", "name": "Activator of basal transcription 1", "aln": "-------------------------------------------MVKVGKLVEEQKAAMEEEKEV----NAEAAEELEEAEEASCNGS---KKKVVP-----------------GIVYLGHVPPRFRPLHVRNLLSVYGEVGRVFFQAEDPFVRRKKKAAAAAGGKKGAKYSKDYTEGWVEFRDKRIAKRVAASLHNTPMGARKRSPFRYDLWNLKYLHRFTWSHLSEHLAFERQVRRQRLRAEVAQAKRETDFYLRNVEQGQRFLAADGDATRPNSSWTFTQRPTEQELRAQKGARPGGRERARLATVQDQARSNRGLLARIFGASLLAESRKEP------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYL7-1", "uniprot_id": "ABT1_MOUSE", "id": "Q9QYL7-1", "name": "Activator of basal transcription 1", "aln": "-------------------------------------------MVKAGELVEQQKAAMEEEA------NAEAAEDQEEPEDTACSSSSKKKKKVVP-----------------GIVYLGHVPPRFRPLHVRNLLSAYGEVGRVFFQAEDHFVKRKKKAAAAAGGKKGAKYSKDYTEGWVEFRDKRVAKRVAASLHNTPMGARKRSPFRYDLWNLKYLHRFTWSHLSEHLAFERQVRRQRLRAEVAQAKRETDFYLRNVEQGQHFLAADGDATRPNSSWTFTQRPTEQEFRARKAARPGGRERARLANVEDQARSNRGLLAKIFGAPLPAESKEKP------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULW3-1", "uniprot_id": "ABT1_HUMAN", "id": "Q9ULW3-1", "name": "Activator of basal transcription 1", "aln": "-----------------------------------------------MEAEESEKAATEQEPLEGTEQTLDAEEEQEESEEAACGSK----KRVVP-----------------GIVYLGHIPPRFRPLHVRNLLSAYGEVGRVFFQAEDRFVRRKKKAAAAAGGKK-RSYTKDYTEGWVEFRDKRIAKRVAASLHNTPMGARRRSPFRYDLWNLKYLHRFTWSHLSEHLAFERQVRRQRLRAEVAQAKRETDFYLQSVERGQRFLAADGDPARPDGSWTFAQRPTEQELRARKAARPGGRERARLATAQDKARSNKGLLARIFGAPPPSESMEGPSLVRDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53743-1", "uniprot_id": "ESF2_YEAST", "id": "P53743-1", "name": "Pre-rRNA-processing protein ESF2", "aln": "MSEKVNSDFEDFSSDEETDQHNVLIQTKKKISSKDDIFSKKVEDIESENESDIEEEQKQEEKEDVEQPDKENGEKLDREVEEQASSTTSLDLKTEKLRQLVKSKAAKKSKHKTGVVYFSSIPPYMKPAKMRQILTRFGEVDRLFLKKEDDQKYKQR-------VKGGGNKKNKYEEGWAEFIRKRDAKLCAETLNGNIIGGKKGTFYHDDILNVKYLPGFKWADLTEQIARENDIRQAKLEMEISQANKLNAEFIRNVEQSKMIQNIKNSRKRAGKEGESADSHPHREFKQRRVETSRANAPSDIKQQSSGSKDLGNVLTNLL------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * : :. : *:: :. :* : ::::: .. :.* :.: : . :**.** * ** . *: . : . : : : :::* *.* * : : . . . :. . ", "identical_positions": 16, "similar_positions": 48, "identity": "4.69%" }, { "cls_id": "homologset.agr.SGD:S000005347", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P34914-1", "uniprot_id": "HYES_MOUSE", "id": "P34914-1", "name": "Bifunctional epoxide hydrolase 2", "aln": "MALRVAAFDLDGVLALPSIAGAFRRSEEALALPRDFLLGAYQTEFPEGPTEQLMKGKITFSQWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTCIVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEVVFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFP-----------EAPLPVPCNPNDVSHGYVTVKPGIRLHFVEMG---SGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSSSPPEIEEYAMELLCKEMVTFLDKLGIPQ--AVFIGHDWAGVMVWNMALFYPERVRAVASLNTPFMPPDPDVSPMKVIRSIPVFN----YQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAVHKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTG-FRGPLNWYRNTERNWKWSCKGL--GRKILVPALMVTAEKDIVLRPEMSKNMEKWIP--FLKRGHIEDCGHWTQIEKPTEVNQILIKWLQTEVQNPSVTSKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P80299-1", "uniprot_id": "HYES_RAT", "id": "P80299-1", "name": "Bifunctional epoxide hydrolase 2", "aln": "MALRVAAFDLDGVLALPSIAGVLRHTEEALALPRDFLLGAFQMKFPEGPTEQLMKGKITFSQWVPLMDESCRKSSKACGASLPENFSISEIFSQAMAARSINRPMLQAAAALKKKGFTTCIVTNNWLDDSDKRDILAQMMCELSQHFDFLIESCQVGMIKPEPQIYKFVLDTLKAKPNEVVFLDDFGSNLKPARDMGMVTILVRDTASALRELEKVTGTQFP-----------EAPLPVPCSPNDVSHGYVTVKPGIRLHFVEMG---SGPAICLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSSSPPEIEEYAMELLCEEMVTFLNKLGIPQ--AVFIGHDWAGVLVWNMALFHPERVRAVASLNTPLMPPNPEVSPMEVIRSIPVFN----YQLYFQEPGVAEAELEKNMSRTFKSFFRTSDDMGLLTVNKATEMGGILVGTPEDPKVSKITTEEEIEYYIQQFKKSG-FRGPLNWYRNTERNWKWSCKAL--GRKILVPALMVTAEKDIVLRPEMSKNMENWIP--FLKRGHIEDCGHWTQIEKPAEVNQILIKWLKTEIQNPSVTSKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P34913-1", "uniprot_id": "HYES_HUMAN", "id": "P34913-1", "name": "Bifunctional epoxide hydrolase 2", "aln": "MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNT---------PAPLPTSCNPSDMSHGYVTVKPRVRLHFVELG---SGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQ--AVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFD----YQLYFQEPGVAEAELEQNLSRTFKSLFRASDES-VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSG-FRGPLNWYRNMERNWKWACKSL--GRKILIPALMVTAEKDFVLVPQMSQHMEDWIP--HLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARNPPVVSKM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IE26-1", "uniprot_id": "EPHX4_MOUSE", "id": "Q6IE26-1", "name": "Epoxide hydrolase 4", "aln": "------------------------------------------------------------------------------------------------------MAPPR------PPRLLPALRALLYWSLVYGYCGLCASVHLLKLLWSIGRAPAQT------------FRRAARANPPACLNDPSLGTHCYVRIK----------------------------------------------------------DSGLRFHYVAAGE-RGKPLMLLLHGFPEFWYSWRHQLREFKSE-YRVVALDLRGYGESDAPAHQESYKLDCLIADIKDILDSLGYSK--CVLIGHDWGGMIAWLIAVCYPEMIMKLIVINFPHPSVFTEYI-LRHPAQLFRSS----FYYFFQIPRFPEFMFSINDFKALKHLFTS--------------------QSTGIGRKGRQLTTEDLEAYVYVFSQPGALSGPINHYRNIFSCLPLKHH------MVTTPTLLLWGEEDAFMEVEMAEVT-KIYVKNYFRLTILSEGSHWLQQDQPDIVNGLIWAFLKEETRRD------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZKP8-1", "uniprot_id": "D3ZKP8_RAT", "id": "D3ZKP8-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------MAPPR------PPRLLPALRALLYWSLVYGYCGLCASVHLLKLLWSIGRAPAQT------------FRRAARANPPACLNDPSLGTHCYVRIKVKAVAGLETGEGEGRGWEPREPRCLGLRADYSSPDSCGHPEDPRGGRRDWAGGLFRARDSGLRFHYVAAGE-RGKPLMLLLHGFPEFWYSWRHQLREFKSE-YRVVALDLRGYGESDAPIHQESYKLDCLIADIKDVLDSLGYNK--CVLIGHDWGGMIAWLIAVCYPEMIMKLIVINFPHPSVFTEYI-LRHPAQLFRSS----FYYFFQIPRLPELMFSINDFKALKHLFTS--------------------QSTGIGRKGRQLTTEDLEAYVYVFSQPGALSGPINHYRNIFSCLPLKHH------MVTTPTLLLWGEEDAFMEVEMAEVT-KIYVKNYFRLTILSEGSHWLQQDQPDIVNGLIWAFLREETRRD------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IUS5-1", "uniprot_id": "EPHX4_HUMAN", "id": "Q8IUS5-1", "name": "Epoxide hydrolase 4", "aln": "------------------------------------------------------------------------------------------------------MARLRD----CLPRLMLTLRSLLFWSLVYCYCGLCASIHLLKLLWSLGKGPAQT------------FRRPAREHPPACLSDPSLGTHCYVRIK----------------------------------------------------------DSGLRFHYVAAGE-RGKPLMLLLHGFPEFWYSWRYQLREFKSE-YRVVALDLRGYGETDAPIHRQNYKLDCLITDIKDILDSLGYSK--CVLIGHDWGGMIAWLIAICYPEMVMKLIVINFPHPNVFTEYI-LRHPAQLLKSS----YYYFFQIPWFPEFMFSINDFKVLKHLFTS--------------------HSTGIGRKGCQLTTEDLEAYIYVFSQPGALSGPINHYRNIFSCLPLKHH------MVTTPTLLLWGENDAFMEVEMAEVT-KIYVKNYFRLTILSEASHWLQQDQPDIVNKLIWTFLKEETRKKD-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ILH2-1", "uniprot_id": "A0A0R4ILH2_DANRE", "id": "A0A0R4ILH2-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------MARLLHNLLLLTVGLTLKIRVMGYWSLIYGYCALCTGVALIKLGWNIILRPSTT------------FQWTVREIPPSCLNDTSLGTHCYVRIK----------------------------------------------------------ESGLRFHYVAAGE-RGKPLMLFLHGFPEFWFSWRHQLREFKSE-FRVVAVDMRGYGESDLPSSTESYRLDYLVTDIKDIVEYLGYNR--CFLVGHDWGGIIAWLCAIHYPEMVTKLIVLNSPHPCVFTDYA-LRHPSQMLKSS----YYFFFQLPYFPELMLSINDFKALKSLFTS--------------------RSTGISCKGRWLTTEDLEAYLYALSQPGALTGALNYFRNVFSVLPLSHS------EVKSPVLLLWGERDAFLEQDMAEAC-RLYIRNLFRLNIISGASHWLQQDQPDIVNKLIWTFIKEGEGRKNYRNL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3V1F8-1", "uniprot_id": "EPHX3_MOUSE", "id": "Q3V1F8-1", "name": "Epoxide hydrolase 3", "aln": "------------------------------------------------------------------------------------------------------MPEFVVTALLAPSRLSLKLLRALVMSLVYLAALVAAFVYSCIALTHVMCRPRRG------------CCGRQRLSPPECLRDPTLGEHCFLTLRVSVPP---------------------------------------------------VKSSGLRLHYVSAGH-GNGPLMLFLHGFPENWFSWRYQLREFQSH-FHVVAVDMRGYSPSDAPKEVDCYTIDLLLDDIKDTILGLGYSK--CILVSHDWGASLAWEFSIYYPSLVERMVVANGPPMSVIQEYS-IHHIGQIFRSN----YMFLFQLPWLPEKLLSMSDFQILKDTFTH--------------------RKNGIPG----LTPSELEAFLYHFSQPGCLTGPINYYRNVFRNFPLEPK------KLSTPTLLLWGEKDFAFQQGLVEAIGRHFVPGRLESHILPGSGHWIPQSHPQEMHQYMWAFLQDLLG--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A4W4-1", "uniprot_id": "D4A4W4_RAT", "id": "D4A4W4-1", "name": "", "aln": "----------------------------------------------MCGGSLYPSRASVSSAGPVDPDSTVETQNKGGGLPAPAPPAQSSDHGSVVVPERKDMPEFVVTALLAPSRLSLKLLRALVMILVYLAALVAAFVYSCVALTNVLCHPRRG------------CCGRQR-SAPECLRDPTLGEHCFLTLR----------------------------------------------------------SSGLRLHYVSAGR-GNGPLMLFLHGFPENWFSWRYQLREFQSH-FHVVAVDLRGYSPSDAPKDVDCYTVDLLLTDIKDIILGLGYSK--CILVSHDWGAALAWDFSVYFPSLVDRMIVVSGPPMSVFQEYS-TRHIGQLFRSN----YIFLFQLPWLPEKLLSLSDFQILKSIFTH--------------------HKKGIPR----LSPCELEAFLYPFSHPGGLSGPINYYRNVFRNFPLEPK------ELSKPTLLLWGEKDFSLQQGLVEAIESHFVPGRLESHILPGSGHWIPQSHPEEMHQYMWAFLQDLLG--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H6B9-1", "uniprot_id": "EPHX3_HUMAN", "id": "Q9H6B9-1", "name": "Epoxide hydrolase 3", "aln": "------------------------------------------------------------------------------------------------------MPELVVTALLAPSRLSLKLLRAFMWSLVFSVALVAAAVYGCIALTHVLCRPRRG------------CCGRRRSASPACLSDPSLGEHGFLNLK----------------------------------------------------------SSGLRLHYVSAGR-GNGPLMLFLHGFPENWFSWRYQLREFQSR-FHVVAVDLRGYGPSDAPRDVDCYTIDLLLVDIKDVILGLGYSK--CILVAHDWGALLAWHFSIYYPSLVERMVVVSGAPMSVYQDYS-LHHISQFFRSH----YMFLFQLPWLPEKLLSMSDFQILKTTLTH--------------------RKTGIPC----LTPSELEAFLYNFSQPGGLTGPLNYYRNLFRNFPLEPQ------ELTTPTLLLWGEKDTYLELGLVEAIGSRFVPGRLEAHILPGIGHWIPQSNPQEMHQYMWAFLQDLLD--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XI64-1", "uniprot_id": "ABHD6_RAT", "id": "Q5XI64-1", "name": "Monoacylglycerol lipase ABHD6", "aln": "--------------------------------------------------------------------------------------------------------------------MDLDVVNMFVIAGGTLAIPILAFVASFLLWPSALIR------------------------IYYWYWRRTLGMQVRYVHH-----------------------------------------------------------EDYQFCYSFRGRPGHKPSVLMLHGFSAHKDMWLSVVKFLPKN-LHLVCVDMPGHEGTTR-SSLDDLSIVGQVKRIHQFVECLKLNKKPFHLIGTSMGGNVAGVYAAYYPSDVCSLSLVCPAGLQYSTDNRFVQRLKELEDS------AATQKIPLIPSTPEEMSEMLQLCSYVRFK-------------------------------VPQQILQGLVDVRIPHNSFYRKLFLEIVSEKSRYSLHEN--MDKIKVPTQIIWGKQDQVLDVSGADILAKSIT--NSQVEVLENCGHSVVMERPRKTAKLVVDFLASVHNPDNNKKLN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2Y0-1", "uniprot_id": "ABHD6_MOUSE", "id": "Q8R2Y0-1", "name": "Monoacylglycerol lipase ABHD6", "aln": "--------------------------------------------------------------------------------------------------------------------MDLDVVNMFVIAGGTLAIPILAFVASFLLWPSALIR------------------------IYYWYWRRTLGMQVRYAHH-----------------------------------------------------------EDYQFCYSFRGRPGHKPSILMLHGFSAHKDMWLSVVKFLPKN-LHLVCVDMPGHEGTTR-SSLDDLSIVGQVKRIHQFVECLKLNKKPFHLIGTSMGGHVAGVYAAYYPSDVCSLSLVCPAGLQYSTDNPFVQRLKELEES------AAIQKIPLIPSTPEEMSEMLQLCSYVRFK-------------------------------VPQQILQGLVDVRIPHNSFYRKLFLEIVNEKSRYSLHEN--MDKIKVPTQIIWGKQDQVLDVSGADILAKSIS--NSQVEVLENCGHSVVMERPRKTAKLIVDFLASVHNTDN-KKLN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BV23-1", "uniprot_id": "ABHD6_HUMAN", "id": "Q9BV23-1", "name": "Monoacylglycerol lipase ABHD6", "aln": "--------------------------------------------------------------------------------------------------------------------MDLDVVNMFVIAGGTLAIPILAFVASFLLWPSALIR------------------------IYYWYWRRTLGMQVRYVHH-----------------------------------------------------------EDYQFCYSFRGRPGHKPSILMLHGFSAHKDMWLSVVKFLPKN-LHLVCVDMPGHEGTTR-SSLDDLSIDGQVKRIHQFVECLKLNKKPFHLVGTSMGGQVAGVYAAYYPSDVSSLCLVCPAGLQYSTDNQFVQRLKELQGS------AAVEKIPLIPSTPEEMSEMLQLCSYVRFK-------------------------------VPQQILQGLVDVRIPHNNFYRKLFLEIVSEKSRYSLHQN--MDKIKVPTQIIWGKQDQVLDVSGADMLAKSIA--NCQVELLENCGHSVVMERPRKTAKLIIDFLASVHNTDNNKKLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53750-1", "uniprot_id": "YN93_YEAST", "id": "P53750-1", "name": "Uncharacterized hydrolase YNR064C", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNIIARFHKIQVQ-----------------------------------------------------------DGVKVWYREAGA-AGNPTILLLHGFPTSSNMFRNLIPLLAGQ-FHIIAPDLPGFGFTETPENYK-FSFDSLCESIGYLLDTLSIEK--FAMYIFDYGSPVGFRLALKFPSRITGIVTQNGNAYEEGLDDRFWGPLKEYWKSYQSDPVFVKSLIPYLEDPANVICQYHDGVPAIES-------------------------------VDPAAYTLDIALIQRTGQTDIQLRLFFDYQNNIKLYPAFQKFLRDSKIPVLVAWGANDTIFSVAGAEAYRKDVDN---LKVVYYDTGHFALETHVVAIAEEIISMFAEN----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :. : * * : : ***. : : : :::. *: *. : . . : : * : : . .. : : .*. : : : * . . . : . . *. : . .* : . .* . : : ", "identical_positions": 13, "similar_positions": 50, "identity": "2.25%" }, { "cls_id": "homologset.agr.SGD:S000005348", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZW09-1", "uniprot_id": "D3ZW09_RAT", "id": "D3ZW09-1", "name": "VPS10 domain-containing receptor SorCS2", "aln": "----------------------------MAHRGTPSAPKRPGLTAPDRSSQVLLPPC-----------WPRSWP-----LLLLLLVLVAACGAMGRSPQPGRWGPSVQVTRLL---PAGRTESSNRQDPQTRESE----------------------------------PGVPGLRPGSASGPSTDGAPAL----GKGRR------------------VRAAPVAGAASASRAQVSLISTSFVLKGDATHNQAMVHWTGE------------------------NSSVILILTKYYHADM-GKVLESSLWRSSDFGTTYTKLTLQPG---VTTVIDNFYICPANKRKIILVSSSLGDREQSLFLSTDEGTTFQKYPVPFLVETLLFHP-KEEDKVLAYTKDS---KLYVSSDLGKKWTLLQEQVTKDHVFWAVSGVDDDPNLVHMEARDLSGGYRYYTCLIHNCSAQPHTAPFPGPTDRGSLTVQDEYIFLKATSTN-------RTKYYVSYRRSDFVLMKLPKYALPKLFCPQDLQIISTDEQQVFVAVQE--WNQVDTYNLYQSDLRGVRYSLVLENVRSSRQAEENV-----------VIDILEVRGVKGVFLANQKV----------DGKVTTVITYNKGRDWDYLRPPSTDMNGKPTNCQ--PPD-CHLHLHLRWADNPYVSGT---VHTKDTAPGLIMGAGNLGSQLV-EYKEEMYITSDCGHTWRQVFEEEHHVLYLDHGGVIAAIKDT-SIPLKTLKFSVDEGHTWSTHNFTSTSVFVDGLLSEPGDETLVMTVFG--HISFRSDWELVKVDFRPSFPRPCVEDDYSSWDLTDL-----QGDHCIMGQQRSYRKRKSTSWCVKGRSFTSALT-SRVCKCRDSDFLCDYGFERSSSSESTVNKCSANFWFNPLSPPEDCVLGQTYTSSLGYRKVVSNVCEGGVDLQQSPVQLQCPLQAPRG-------------LQVSIRGEAVAVRPREDVLFVVRQEQGDVLTTKYQVDLGDGFKAMYVNLTLTGEPIRHHYESPGIYRVSVRAENMAGHDEAVLFVQVNSPLQALYLEVVPVIGINQEVNLTAVLLPLNPNLTVFYWWIGHSLQPLLSLDNSVTTRFTDAGDVRVTVQAACGNSVLQDSRLVRVLDQFQVVPLQFSRDLDTFNP----------------------NTPEWREDVGLVVTRLLSKETSIPEELLVTVVKPGLPTIADLYVLLPPPRPTRKRSLTS---DKRLAAVQQALNSHRISFILRGGLRVLVELRDTDAGPQR------------------------PGGSGGYWAVVVLFVIGLFAVGAFILYKFKRK-------------------------RPGRTVYAQMHNEKEQ-EMTSPVSHSEDAQSAMQG--------------------------------------------NHSGVVLSINSREMHSYLVG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPR5-1", "uniprot_id": "SORC2_MOUSE", "id": "Q9EPR5-1", "name": "VPS10 domain-containing receptor SorCS2", "aln": "----------------------------MAHRGPPSAPKRPGPTAPDRSFQALLPPC-----------WPRSWP-----LLLLLLVLVAACGAMGRSPQPGRQGPGVQITRLL---PAGRTESGDRKDPQARESE----------------------------------PSVPGLGPGSASGPSTDGAPAP----GKGRR------------------ARAVPVAGAASASRAQVSLISTSFVLKGDATHNQAMVHWTGE------------------------NSSVILILTKYYHADM-GKVLESSLWRSSDFGTTYTKLTLQPG---VTTVIDNFYICPANKRKIILVSSSLGDREQSLFLSTDEGATFQKYPVPFLVEMLLFHP-KEEDKVLAYTKDS---KLYVSSDLGKKWTLLQERVTKDHVFWAVSGVDDDPNLVHVEAQDLSGGYRYYTCLIYNCSAQPHIAPFSGPIDRGSLTVQDEYIFLKATSTN-------RTKYYVSYRRSDFVLMKLPKYALP-----KDLQIISTDEQQVFVAVQE--WNQVDTYNLYQSDLRGVRYSLVLENVRSSRQAEENV-----------VIDILEVRGVKGVFLANQKV----------DGKVTTVITYNKGRDWDYLRPPSTDMNGKPTNCQ--PPD-CYLHLHLRWADNPYVSGT---VHTKDTAPGLIMGAGNLGSQLV-EYKEEMYITSDCGHTWRQVFEEEHHVLYLDHGGVIAAIKDT-SIPLKILKFSVDEGHTWSTHNFTSTSVFVDGLLSEPGDETLVMTVFG--HISFRSDWELVKVDFRPSFPRQCGEDDYSSWDLTDL-----QGDHCIMGQQRSYRKRKSTSWCVKGRSFTSALT-SRVCKCRDSDFLCDYGFERSSSSESTANKCSANFWFNPLSPPEDCVLGQTYTSSLGYRKVVSNVCEGGVDLQQSPVQLQCPLQAPRG-------------LQVSIRGEAVAVRPREDVLFVVRQEQGDVLTTKYQVDLGDGFKAMYVNLTLTGEPIRHHYESPGIYRVSVRAENMAGHDEAVLFVQVNSPLQALYLEVVPVIGVNQEVNLTAVLLPLNPNLTVFYWWIGHSLQPLLSLDNSVTTKFTDAGDVRVTVQAACGNSVLQDSRLVRVLDQFQVVPLRFSRELDTFNP----------------------NTPEWREDVGLVVTRLLSKETSIPEELLVTVVKPGLPTIADLYVLLPLPRPTRKRSLTS---DKRLAAVQQALNSHRISFILRGGLRILVELRDTDTGPQR------------------------PGGSGGYWAVVVLFVIGLFAVGAFILYKFKRK-------------------------RPGRTVYAQMHNEKEQ-EMTSPVSHSEDAQSTMQG--------------------------------------------NHSGVVLSINSREMHSYLVG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PQ0-1", "uniprot_id": "SORC2_HUMAN", "id": "Q96PQ0-1", "name": "VPS10 domain-containing receptor SorCS2", "aln": "----------------------------MAHRGPSRASKGPGPTARAPSPGAPPPPR-----------SPRSRP-----LLLLLLLLG-ACGAAGRSPEPGRLGPHAQLTRVPRSPPAGRAEPGGGEDRQARGTE----------------------------------PGAPGPSPGPAPGPGEDGAPAA----GYRRW------------------ERAAPLAGVAS--RAQVSLISTSFVLKGDATHNQAMVHWTGE------------------------NSSVILILTKYYHADM-GKVLESSLWRSSDFGTSYTKLTLQPG---VTTVIDNFYICPTNKRKVILVSSSLSDRDQSLFLSADEGATFQKQPIPFFVETLIFHP-KEEDKVLAYTKES---KLYVSSDLGKKWTLLQERVTKDHVFWSVSGVDADPDLVHVEAQDLGGDFRYVTCAIHNCSEKMLTAPFAGPIDHGSLTVQDDYIFFKATSAN-------QTKYYVSYRRNEFVLMKLPKYALP-----KDLQIISTDESQVFVAVQE--WYQMDTYNLYQSDPRGVRYALVLQDVRSSRQAEESV-----------LIDILEVRGVKGVFLANQKI----------DGKVMTLITYNKGRDWDYLRPPSMDMNGKPTNCK--PPD-CHLHLHLRWADNPYVSGT---VHTKDTAPGLIMGAGNLGSQLV-EYKEEMYITSDCGHTWRQVFEEEHHILYLDHGGVIVAIKDT-SIPLKILKFSVDEGLTWSTHNFTSTSVFVDGLLSEPGDETLVMTVFG--HISFRSDWELVKVDFRPSFSRQCGEEDYSSWELSNL-----QGDRCIMGQQRSFRKRKSTSWCIKGRSFTSALT-SRVCECRDSDFLCDYGFERSSSSESSTNKCSANFWFNPLSPPDDCALGQTYTSSLGYRKVVSNVCEGGVDMQQSQVQLQCPLTPPRG-------------LQVSIQGEAVAVRPGEDVLFVVRQEQGDVLTTKYQVDLGDGFKAMYVNLTLTGEPIRHRYESPGIYRVSVRAENTAGHDEAVLFVQVNSPLQALYLEVVPVIGLNQEVNLTAVLLPLNPNLTVFYWWIGHSLQPLLSLDNSVTTRFSDTGDVRVTVQAACGNSVLQDSRVLRVLDQFQVMPLQFSKELDAYNP----------------------NTPEWREDVGLVVTRLLSKETSVPQELLVTVVKPGLPTLADLYVLLPPPRPTRKRSLSS---DKRLAAIQQVLNAQKISFLLRGGVRVLVALRDTGTGAEQ------------------------LGGGGGYWAVVVLFVIGLFAAGAFILYKFKRK-------------------------RPGRTVYAQMHNEKEQ-EMTSPVSHSEDVQGAVQG--------------------------------------------NHSGVVLSINSREMHSYLVS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G5D7-1", "uniprot_id": "A0AC58G5D7_DANRE", "id": "A0AC58G5D7-1", "name": "VPS10 domain-containing receptor SorCS2", "aln": "-----------------------------------------MKTLIMAVFAHLYPAV-----------FFACAW-----MALLGPISCHSSGIIKQRSERDR-------------------ELDSRGGHVTGTDE----------------------------------ALISAYSRGDYSG--DPGGAAV----GVPRV------------------RRAS--------TPEKVSLLSSSFVLKGDATHNQAMVHWTGE------------------------NSSVILILTKYYHADS-NKVLESSLWRSSDYGSTYTKLNLMPG---TTIIVTNFYICPTNKKKVILVSSSINERDQMLFISTDEGASFQRQPVSFTVDSLLFHP-SEEDKLLAYSKEA---KLYISTDLGHKWTLLQERVTKDRVFWAVTGVDVDPDLVHMEMQDISGGYLYVTCLIQNCSDKMVTAQFLGKIDHNSLSVQDEYIFVKVTTGN-------RTKYYVSYRRNEFVQMRFPKYSLP-----KDVQIVSTDENQVFLALQE--WYQTDTYNLYQSDPQGVYYSIVLENVRSTKQPEENV-----------LIDILEVRGVKGVFLANQKV----------DGKVMTLITYNKGRDWEALAPPATDMNGKPVSCK--QPD-CHLHLHLRWADNPYVSGT---VHTKDSAPGLIMGAGNLGSQLV-EYKEEMYITADCGKTWRQVFEEEHHILYLDHGGVIVAIKDT-SIPLKILKFSIDEGRTWSIHNFTSTSVFVDGLLSEPGDETLVMTVFG--HISYRSDWELVKVDFRQSFPRQCTEADYDSWKLTDL-----QGEKCIMGQERVYRRRKETSFCIKGKSYTSALT-AKPCPCSEKDFTCDYGFERAPSLRLEGDRCYPDFWHNPDAPPENCHLGHSYKSSTGYRKVIANVCEGGLNKEQSAKQHSCPLLPPKG-------------LQLGIKGQMLAVAPGDDITFIVHQEQGDTSSTRYQVDLMDGVRAIYENLTVTDEPIQHRYEKPGVYRVNVKAENSAGHDQAMLYIQVTAPLQDVHLEVVPIAGRNQDVNLTAIVLPTEANLTVFYWWIGDNMQPKLTLENSLITRFSEEGEVPVTVQASNGRSMVQDSKTVIVYDHFQIIPLSFSRNLDHFNP----------------------NIPEWRRDVGEVVTKIIAKLTGVPQEHLVTMLKPGLPTSADLYVLPQETTP-VKRSVFV---DKRVPTIKQVLSENNVSFIVRGGLRVLVTLADLDSGPITSDVSVSTTETATQLTSST-QGSGLAAAGPGVWAVAVFLLISLISAAAFILFKFKRKNYKNHGWLLRPEESSLTRPWLRFRKLPGRNVYAQMHNEKEQ-EMTSPVNHSEDTQNIIQGE------------------------------EFIDDDLDSQTLGNHSGVVLSINSRELHSYLTS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9JLC4-1", "uniprot_id": "SORC1_MOUSE", "id": "Q9JLC4-1", "name": "VPS10 domain-containing receptor SorCS1", "aln": "---------------MGK-VGAGDGSSAGLSALLAGAGLLMLLAPGVCSSLSCCPPQ-----------HPSSTP-----RRTLTPRGFPHPGPLGRAPAT-PPPLFMRPLFAVAP-GDRALFLERAGGSRVSVATAARSGR-----RRRSGTEPEKIE-----------PGEGASR--SRRDMLKDGGQ-----QGLGTG-----------------ARDPGKATRF---RMEELRLTSTTFALTGDSAHNQAMVHWSGH------------------------NSSVILILTKLYDYNL-GSITESSLWRSTDYGTTYEKLNDKVG---LKTILSYLYVCPTNKCKIMLLTD--PEIESSLLISSDEGATYQKYRLNFYLQSLLFHP-KQEDWILAYSQDQ---KLYSSAEFGRRWQLIQESVVPNRFYWSVMGSSKEPDLVHLEARTVDGHSIYLTCRMQNCTEANRNKPFPGYIDPDSLIVQDDYVFVQLTSGG-------RPHYYVSYRRSPFAQMKLPKYALP-----KDMHVISTDENQVFAAVQE--WNQNDTYNLYISDTRGVYFTLALENVRSSRGPEGNV-----------MIDLYEVAGIKGMFLANKKI----------DNQVKTFITYNKGRDWRLLQAPDADLRGDPVHCL--LPY-CSLHLHLKVSENPYTSGI---IASRDTAPSIIVASGNIGSELS-DSDISMFVSSDAGNTWRQIFEEEHSILYLDQGGVLVAMKHT-SLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFG--HFSHRSEWQLVKVDYKSIFDRRCAEEDYRPWQLHS------QGEACIMGAKRIYKKRKSERKCMQ--KYAGAME-SEPCVCTEADFDCDYGYERHSN-----GQCLPAFWFNPSSLSKDCSLGQSYLNSAGYRKVVSNNCTDGVREQYTAKPQKCPGKAPRG-------------LRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDGIAVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFVTTKNKEVNATAVLWPSQVGTLTYVWWYGNNTEPLITLEGSISFKFTSEGMNTITVQVSAGNAILQDTKTIAVYEEFRSLRLAFSPNLDDYNP----------------------DIPEWRRDISRVIKKSLVEATGIPSQHILVAVLPGLPTAAELFVLP-YQDGTRENKRSPEDLEQISEVLIHKLNQNLVHFELKPGVQVLVHAAHLTAAPLVD-----------------------LTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRR-------------------------VA----------------LPSPPSPS-AQPGDSSLRLQRPR------------------------PATPPSSPKRGS---AGAQFAI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AEA1-1", "uniprot_id": "A0A8I6AEA1_RAT", "id": "A0A8I6AEA1-1", "name": "VPS10 domain-containing receptor SorCS1", "aln": "---------------MGK-VGAGDGSSAALSALLTGAGLLMLLAPGICSSLSCCPPQ-----------HPSSTP-----RWTLTPRGFSYPGPLGRAPAT-PPPLFMRPLFAVAP-GDRALFLERAGGSRVSVATASRSGR-----RRRSGMDPEKTE-----------PGEGTSR--SRRDMLRDGGQ-----QGPGTG-----------------ARDPDKATRF---RMEELRLTSTTFALTGDSAHNQAMVHWSGH------------------------NSSVILILTKLYDYNL-GSITESSLWRSTDYGTTYEKLNDKVG---LKTILSYLYVCPTNKRKIMLLTD--PEIESSLLISSDEGATYQKYRLNFYIQSLLFHP-KQEDWILAYSQDQ---KLYSSAEFGRRWQLIQEAVVPNRFYWSVLGSNKEPDLVHLEARTVDGHSIYLTCRMQNCTEANRNKPFPGYIDPDSLIVQDDYVFVQLTSGG-------RPHYYVSYRRNPFAQMKLPKYALP-----KDMHVISTDENQVFAAVQE--WNQNDTYNLYISDTRGVYFTLALENVQSSRGPEGNV-----------MIDLYEVAGIKGMFLANKKI----------DNQVKTFITYNKGRDWRLLQAPDADLRGDPVHCL--LPY-CSLHLHLKVSENPYTSGI---IASRDTAPSIIVASGNIGSELS-DSDISMFVSSDAGNTWRQIFEEEHSILYLDQGGVLVAMKHT-SLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFG--HFSHRSEWQLVKVDYKSIFDRRCAEEDYRPWQLHS------QGEACIMGAKRIYKKRKSERKCMQG-TYAGAME-SEPCVCTEADFDCDYGYERHSS-----GQCLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDGVREQYTAKPQKCPGKAPRG-------------LRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDGIAVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFVTTKNKEVNATAVLWPSQVGTLTYVWWYGNNTEPLITLEGSISFKFTSEGMNTITVQVSAGNAILQDTKTIAVYEEFRSLRLAFSPNLDDYNP----------------------DIPEWRRDISRVIKKSLVEATGIPSQHILVAVLPGLPTAAELFVLP-YQDGARENKRSPEDLEQISEVLIHKLNQNLVHFELKPGVQVLVHAAHLTAAPLVD-----------------------LTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRK-------------------------IPGINVYAQMQNEKEQ-ELINPVSHTESRPTAPHPDLRRPGQLVDEKVESHLL------------DQDKPHHLHRQSGDLLGHNLQSKENPQRLQETC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WY21-1", "uniprot_id": "SORC1_HUMAN", "id": "Q8WY21-1", "name": "VPS10 domain-containing receptor SorCS1", "aln": "---------------MGK-VGAGGGSQARLSALLAGAGLLILCAPGVCGGGSCCPSP-----------HPSSAP-----RSASTPRGFSHQGRPGRAPAT-PLPLVVRPLFSVAP-GDRALSLERARGTGASMAVAARSGR-----RRRSGADQEKAE-----------RGEGASR--SPRGVLRDGGQ-----QEPGTR-----------------ERDPDKATRF---RMEELRLTSTTFALTGDSAHNQAMVHWSGH------------------------NSSVILILTKLYDYNL-GSITESSLWRSTDYGTTYEKLNDKVG---LKTILSYLYVCPTNKRKIMLLTD--PEIESSLLISSDEGATYQKYRLNFYIQSLLFHP-KQEDWILAYSQDQ---KLYSSAEFGRRWQLIQEGVVPNRFYWSVMGSNKEPDLVHLEARTVDGHSHYLTCRMQNCTEANRNQPFPGYIDPDSLIVQDHYVFVQLTSGG-------RPHYYVSYRRNAFAQMKLPKYALP-----KDMHVISTDENQVFAAVQE--WNQNDTYNLYISDTRGVYFTLALENVQSSRGPEGNI-----------MIDLYEVAGIKGMFLANKKI----------DNQVKTFITYNKGRDWRLLQAPDTDLRGDPVHCL--LPY-CSLHLHLKVSENPYTSGI---IASKDTAPSIIVASGNIGSELS-DTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAMKHT-SLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFG--HFSHRSEWQLVKVDYKSIFDRRCAEEDYRPWQLHS------QGEACIMGAKRIYKKRKSERKCMQG-KYAGAME-SEPCVCTEADFDCDYGYERHSN-----GQCLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDGVREQYTAKPQKCPGKAPRG-------------LRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDGIAVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFVTTKNKEVNATAVLWPSQVGTLTYVWWYGNNTEPLITLEGSISFRFTSEGMNTITVQVSAGNAILQDTKTIAVYEEFRSLRLSFSPNLDDYNP----------------------DIPEWRRDIGRVIKKSLVEATGVPGQHILVAVLPGLPTTAELFVLP-YQDPAGENKRSTDDLEQISELLIHTLNQNSVHFELKPGVRVLVHAAHLTAAPLVD-----------------------LTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRR-------------------------VA----------------LPSPPSPS-TQPGDSSLRLQRAR------------------------HATPPSTPKRGS---AGAQYAI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PN08-1", "uniprot_id": "A0A8M9PN08_DANRE", "id": "A0A8M9PN08-1", "name": "", "aln": "---------------MERGIRYCRVHVRAFCTLLLILFAWVPVAETVITCRSCHLLD-----------KWSGRE-----LLVKMDSGVDS-GKVGDQDGD-GSLFNLAGAETGQPDCGASDSGEHAHSVRKRNTESLRSGKTPPDEKWKSMRSHDKVYNLKLAASRATAPGDPHHR--VRRGTQEPGSPPGARFQPLGFGNVTARAARRVPRSELRWNRDERRTAAS---RQEELKLTSSTFALTGDSAHNQAMVHWSGQ------------------------NSSVILMLTKLYDFNL-GSVTESSLWRSTDYGTTYEKLNEKVG---VKTILSYLYVSPNNKRKIMLLTD--PEVESSLLISSDEGATYQKYRLNFYILSLLFHP-EQEDWILAYSHEQ---KLYSSVEFGRRWQLVHERVAPNRFYWSKTGLDKEPGLIHLETSISESQALYVTCKLQNCTDANKGKPFPGYIDPNSLVVQDEYVFVQVSTGG-------RPIYYVSSRRDVFTPMKLPKYTLP-----KDLHVISTDENRVVAAVQE--WNQNDTYNLYVSESGGIYYTLALENVMSSMGPEGNV-----------MIDLYEVAGIKGMFLANKKL----------NNEVKTYITYNKGRDWRLLQAPSADLRGNRIHCM--LPY-CSLHLHLHVSANPYTSGN---IASRESAPGIILASGSIGAELT-SSNVSMFITSDAGNTWRQIFDEEYSVLYLDQGGALVAIRHT-PLPIRHLWLSFDEGRVWNKYSFTSSPLFVDGVLGEPGEETLIMTIFG--HVSHRSEWQLVKIDFRSIFNRRCVESDYVPWDLHD------QGERCLMGVKRVYRKLKATARCVMGKTYSVTMI-SEPCHCTESDFECDYGFERRTD-----GKCTPAFWFPPSSMSRTCTTEHTFLNSTGYRKVVSNNCTGGVIERYTARRQLCPSQAPRG-------------LHLVTSEGKLTATLASNVTFLVFLEEGDGSKTSITVDFGDGNAFTYSNVSSIEDGIKHIYKTVGIYRVSATAENSLGSETVLLFLHVTCQLDSIHLSAPFVAVKNKEVNLTVVLYPSQVGTVTYIWWFGNNSEPVITLDGSVSFTFSREGISIVTVQVSAGNNILQDRKTIAVHEYFRSHLLAFSSNLDDHNP----------------------DVAEWRLDVSRVIKTSMMQATGVSPDLLLVTVLPGLPTAAEFFLLPDKQLTEGKPDKTATHLDQLSEVVLSALNQNLVQFTLRPGVQITVYAAHLSAAPLVD-----------------------TSENHSGSAMLMLLSVVVLGLAIFLIYKFKRK-------------------------IPGLHVYAAMQDEKEQEMIQSPVSPTDSTPSSSSQRELLTS------------------------LEPLDTEPNTQTIECIKPHPRVKFSSDLPTYIDV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8VI51-1", "uniprot_id": "SORC3_MOUSE", "id": "Q8VI51-1", "name": "VPS10 domain-containing receptor SorCS3", "aln": "----------MEAAGTERPAGWPGAPLARTGLLLLSTWVLAGAEITWGATGGPGRLV-----------SPASRPP---VLPPLLPRAAENRWPEELASARRAAAPRRRSRLEPLSQASRG---EIRTEAAGMSPEGARWVPGIPSPSQAGSARRTRRAQ----------PPSPLERGDSWATALADGAKGS---RPHTKG-----------------SREEVRATRTGGASTEELRLPSTSFALTGDSAHNQAMVHWSGH------------------------NSSVILILTKLYDFNL-GSVTESSLWRSVDYGATYEKLNDKVG---LKTVLSYLYVNPTNKRKIMLLSD--PEMESSVLISSDEGATYQKYRLTFYIQSLLFHP-KQEDWVLAYSLDQ---KLYSSMDFGRRWQLMHERITPNRFYWSVSGLDKEADLVHMEVRTADGYAHYLTCRIQECAETTRSGPFARSIDISSLVVQDEYIFIQVTIGG-------RASYYVSYRREAFAQIKLPKYSLP-----KDMHIISTDENQVFAAVQE--WNQNDTYNLYISDTRGIYFTLAMENIKSSRGLMGNI-----------IIELYEVAGIKGIFLANKKV----------DDQVKTYITYNKGRDWRLLQAPDVDLRGSPVHCL--LPF-CSLHLHLQLSENPYSSGR---ISSKDTAPGLVVATGNIGSELS-YTDIGVFISSDGGNTWRQIFDEEYNVWFLDWGGALVAMKHT-PLPVRHLWVSFDEGHSWDKYGFTLLPLFVDGALVEAGVETHIMTVFG--HFSLRSEWQLVKVDYKSIFSRRCTKEDFETWHLLN------QGEPCVMGERKIFKKRKPGAQCALGREYSGSVV-SEPCVCADWDFECDYGYERHGE-----SQCVPAFWYNPASPSKDCSLGQSYLNSTGYRRIVSNNCTDGLRDKYSAKTQLCPGKAPRG-------------LHVVTTDGRLVAEQGHNATFIILMEEGDLQRTNIQLDFGDGVAVSYANFSPIEDGIRHVYKSAGIFQVTAYAENNLGSDTAFLFLHVVCPVEHVHLRVPFVAIRNKDVNISAVVWPSQLGTLTYFWWFGNSTKPLITLDSSISFTFLAEGTNTITVQVAAGNALIQDTKEIAVHEYFQSQLLSFSPNLDYHNP----------------------DIPEWRQDIGNVIKRALIKVTSVPEDQILVAVFPGLPTSAELFILPPKNLTERR-KGHEGDLEQIVETLFNALNQNLVQFELKPGVQVIVYVTQLTLAPLVD-----------------------SSAGHSSSAMLMLLSVVFVGLAVFLIYKFKRK-------------------------IPWINIYAQVQHDKEQ-EMIGSVSQSENAPKITLSDFTEPE-------------------------ELLDKELDTRVIGSIATIASSESTKEIPNCTSV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPU3-1", "uniprot_id": "SORC3_HUMAN", "id": "Q9UPU3-1", "name": "VPS10 domain-containing receptor SorCS3", "aln": "----------MEAARTERPAGRPGAPLVRTGLLLLSTWVLAGAEITWDATGGPGRPA-----------APASRPP---ALSPLSPRAVASQWPEELASARRAAVLGRRAGPELLPQQGGGRGGEMQVEAGGTSPAGERRGRGIPAPAKLGGARRSRRAQ----------PPITQERGDAWATAPADGSRGS---RPLAKG-----------------SREEVKAPRAGGSAAEDLRLPSTSFALTGDSAHNQAMVHWSGH------------------------NSSVILILTKLYDFNL-GSVTESSLWRSTDYGTTYEKLNDKVG---LKTVLSYLYVNPTNKRKIMLLSD--PEMESSILISSDEGATYQKYRLTFYIQSLLFHP-KQEDWVLAYSLDQ---KLYSSMDFGRRWQLMHERITPNRFYWSVAGLDKEADLVHMEVRTTDGYAHYLTCRIQECAETTRSGPFARSIDISSLVVQDEYIFIQVTTSG-------RASYYVSYRREAFAQIKLPKYSLP-----KDMHIISTDENQVFAAVQE--WNQNDTYNLYISDTRGIYFTLAMENIKSSRGLMGNI-----------IIELYEVAGIKGIFLANKKV----------DDQVKTYITYNKGRDWRLLQAPDVDLRGSPVHCL--LPF-CSLHLHLQLSENPYSSGR---ISSKETAPGLVVATGNIGPELS-YTDIGVFISSDGGNTWRQIFDEEYNVWFLDWGGALVAMKHT-PLPVRHLWVSFDEGHSWDKYGFTSVPLFVDGALVEAGMETHIMTVFG--HFSLRSEWQLVKVDYKSIFSRHCTKEDYQTWHLLN------QGEPCVMGERKIFKKRKPGAQCALGRDHSGSVV-SEPCVCANWDFECDYGYERHGE-----SQCVPAFWYNPASPSKDCSLGQSYLNSTGYRRIVSNNCTDGLREKYTAKAQMCPGKAPRG-------------LHVVTTDGRLVAEQGHNATFIILMEEGDLQRTNIQLDFGDGIAVSYANFSPIEDGIKHVYKSAGIFQVTAYAENNLGSDTAVLFLHVVCPVEHVHLRVPFVAIRNKEVNISAVVWPSQLGTLTYFWWFGNSTKPLITLDSSISFTFLAEGTDTITVQVAAGNALIQDTKEIAVHEYFQSQLLSFSPNLDYHNP----------------------DIPEWRKDIGNVIKRALVKVTSVPEDQILIAVFPGLPTSAELFILPPKNLTERR-KGNEGDLEQIVETLFNALNQNLVQFELKPGVQVIVYVTQLTLAPLVD-----------------------SSAGHSSSAMLMLLSVVFVGLAVFLIYKFKRK-------------------------IPWINIYAQVQHDKEQ-EMIGSVSQSENAPKITLSDFTEPE-------------------------ELLDKELDTRVIGGIATIANSESTKEIPNCTSV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q0Q0-1", "uniprot_id": "A0A8M9Q0Q0_DANRE", "id": "A0A8M9Q0Q0-1", "name": "", "aln": "---------------METALGVFPGAHFTISTWLILFFPNVKADISCAPCMSPMQVN-----------YAGDEHLRDPPDSGKYPTPPDQKKPKLIAVLYPNIGVPTDGFPGIAPKVETNADGINSRAPLGNFAESALDEELFSDEFMESGRVKRSVPEFMESAR----GADPLSEEQRKTSALRVDGQG----KRAEVR----------------WNREDEQDARVSDSRPEEPKLTSSTFALAGDSAHNHAVVYWSGK------------------------NSSVILILTKLYDFHL-GSVTESTLWRSTDYGSTYERLNDKVG---VKTVLSYLYVCPTNKRKIMVLTD--PEFESSILISSDEGASYQKYRLNFFVLSLLFHH-TQEDWALAYSHDQ---KLYSSFDFGRKWQLVHERVTPNRFYWSVTGLDKEFDLVHMEAHTPDGHCQYVTCRAQACSESSRTHPFPGYIETNSLVVQDEYVFVQVTTTG-------RASYYVSYQREAFIRIKLPKYSLP-----KDMHIVSTDQGQVFTAVQE--WNQNDTYNLYISDTRGIYFTLALENVRTSRGLGGNS-----------MIDLYEVAGIEGMLIANRKV----------ENQVKTYITYNKGRDWRLLQAPSTDLAGNPIHCV--LPF-CSLHLQLQMSENPYLSGS---ISTKSSAPGVIVATGNIGSELS-YNNVAMFISSDAGNNWRQIFEEEHNVWFLDKGGALVAVKQP-TVPTRHLWISFDEGRQWTRHSFSAMPLFVDGVLVEAGAENQIMTFFG--HFSHRSEWQLIKIDYKSVFTRRCTEGDYQTWHLHN------QGEPCIMGQKQIYMKRRPGNYCMVGWDNSRILS-AEPCICRAHDFECDYGFERRGD-----GNCLPAFWFNPSIVSRSCSQGQNFLNSTGYRKVVANNCTKGVKEMYTARKQQCPNRPPRG-------------LVLTTRDEKLTANMGSNVTFLVRLEEGDSMRTNIQLDFGDGTAVSYSNLSWTQEGIKHVYRSAGIFRVTALAENSLGFDTSSLYLHVTCPVEHIQLLAPYVVIKNKEVNLTAVVWPSHFRTLTYFWWLGNSTEPIVTLDSSISHTFSSEGMSTVTVQVSSGDSILQDSRTIAIQEFFKSLLLSFSPNLDEANP----------------------DIPEWRLDVARVIKKAVLQVADVPEEQLLVAVFPGIPTAAELFLLPPRNQSNGR-KQTEEDLEQISEILVNALNQISVEFELKPGSRVIVYITQLTLAPLVD-----------------------SIPRHSSSAMLMLLSVVFLGLAVFLIYKFKRK-------------------------IPWINIYAEVNHEKEQ-EMINTVGQNDATPKITLSEFSTQK-------------------------ELMEKELEARAKR--GVIHTCESTREIPNCTSV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7T6R5-1", "uniprot_id": "A0A8N7T6R5_DANRE", "id": "A0A8N7T6R5-1", "name": "", "aln": "--------------MINKKDALWFESSRTYWTLFCLCVLVPLPARAEITCASCFAPI-----------RRNEEA-----LVEAKVKPSSDFGSVPDDSTDKNWIQALDG-AQLTSKAHRKSSSVSWREKLENAPKSSAEQTG-----EKGGKVYPTWSS----------EEIKVNRREKRSMFPPDHSPG----SRFEFR------------------RTGGVDGIGKSPRQNEPHLITSTFALSGDSAHNQAMVLWSGH------------------------NSSVILILTKLFDFNL-GTVTESSLWRSVDFGTTYEKLTDKVM---IRTMLSYLYVCPTNKRKILILSD--PEVESSLLISSDEGASFQKFNINFYIMSLLFHP-TQENWILAYSHDQ---RLYSSVDFGKKWILVHERVTPGRFYWALSGLDKEADLVHIEARTDSGQMQYITCRAQKCSEEGRQYPFIGRIDTNSLVVQDQYIFLQLTTAG-------RTTYFVSYQRGPFRTIQLPKYCLP-----KDMHIVSTDEGQVLAAVQE--WNENDTYSLYISDTPGVYFTRSLPNLRTSRGLAGNL-----------IVDVYKVSGISGMIIANKKE----------DAQMRTYITYNKGQTWSLLQPPAKDTTGHDVNCN--LPS-CSLHLHLQMSENPYTPDT---ISTKQSAPGIIVATGNIGPELS-FSNTAMFISSDAGNTWRQIFEEEHSVWFLDHGGALLAVTQS-AVPTRYLWISLDEGRHWDKLSFSSTPLFVDGVLMTPETENRIITFFG--HFSYHSDWQLIKIDYSSLFGRKCTDGDFQTWHLHN------KGEVCVMGERQVYMKRKPGTRCTLGREYSRVVS-AEPCICTLYDFECDYGFERQTS-----GKCAPAFWYDVNLPAHTCSYGQRYRNSTGYRRVMLNNCREGLKDTLSPRMQQCKPIAPSG-------------LQLSTINTQLTAVLGTNITFRVALQNGDSLSTSLHVDFGDGISVSYSNISRLGDSITHTYRVAGIFRVSARAQNSQGSDSSSLYLHITSPVERIFLSAPVVVARGREANLTAVLWPSQPRTATFYWWFNNNTEPLITLEGSVSHTFTREGLNPVTVQVSAGGTVLQDVKIITVKDVFRSLLLSFSPNLEEHNP----------------------SVAEWRQDVGRVVRATLAQVCSFPEDQLLVSVFPGSPTAAELFILPETNQSAFR-SHTEEQLNKMSEVFMNALNQNLIQFDLKPDTRVTVSLSQLTLAPLVD-----------------------SSVLPSGSAMLLLVSLGLLGLAILFIYKFKRK-------------------------IPWIHVETEDSHEKEP-EMISAVGQEKNGTRTTATSFTSCSAHNTHTPCPLNTGTHNSFSHLPPPRELMEKELEAHSTGGLGAGERLR-TRQIPNCTNV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O88307-1", "uniprot_id": "SORL_MOUSE", "id": "O88307-1", "name": "Sortilin-related receptor", "aln": "--------------------------------MATRSSRRESRLPFLFALVALLPRG-----------ALGGGW---------TQRLHGGPAPLPQDRGFFVVQGDPRDLRLGTHGDAPG--ASPAARKPLRTRRS----------------------------------------------------------------------------------------------AALQPQPIQVYGQVSLNDSHNQMVVHWAGE------------------------KSNVIVALARDSLALARPKS--SDVYVSYDYGKSFSKISEKLN-FGVGNNSEAVISQFYHSPADNKRYIFVDAYAQYLWITFDFCSTIHGFSIPFRAADLLLHS-KASNLLLGFDRSHPNKQLWKSDDFGQTWIMIQEHVKS--FSWGIDPYDQ-PNAIYIERHEPFGFSTVLRSTDFFQSREN---QEVILEEVRDFQLRDKYMFATKVVHLPGSQQQSSVQLWVSFGRKPMRAAQFVTKHPI-----NEYYIADAAEDQVFVCVSH--SNNS--TNLYISEAEGLKFSLSLENVLYYSPGGAGSDTLVRYFANEPFADFHRVEGLQGVYIATLING------SMNEENMRSVITFDKGGTWEFLQAPAFTGYGEKINCE--LSQGCSLHLAQRLSQLLNLQLRRMPILSKESAPGLIIATGSVGKNLA-SKT-NVYISSSAGARWREALPGPHYYTWGDHGGIIMAIAQG--METNELKYSTNEGETWKTFVFSEKPVFVYGLLTEPGEKSTVFTIFGSNKESVHS-WLILQVNATDALGVPCTENDYKLWSPS-----DERGNECLLGHKTVFKRRTPHATCFNGEDFDRPVV-VSNCSCTREDYECDFGFKMSEDLSLEVCVPDPEFSGKPYSPPVPCPVGSSYRRTRGYRKISGDTCSGGDVEARLEGELVPCPLAEENEFILYAMRKSIYRYDLASGATEQLPLSGLRAAVALDFDYERNCLYWSDLALDTIQRLCLNGSTGQEVIINSGLETVEALAFEPLSQLLYWVDAGFKKIEVANPDGDFRLTIVNSSVLDR--PRALVLVPQEGVMFWTDWGDLKPGIYRSYMDGSAAYRLVSEDVKWPNGISVDSQWIYWTDAYLDCIERITFSGQQRSVILDSLPHPYAIAVFKNEIYWDDWSQLSIFRASKHSRSQVEILASQLTGLMDMKVFYKGKNAGSNACVPQPCSLLCLPKANNSKSCRCPEGVASSVLPSGDLMCDCPQGYQRKNNTCVKEENTCLRNQYRCSNGNCINSIWWCDFDNDCGDMSDERNCPTTVCDADTQFRCQESGTCIPLSYKCDLEDDCGDNSDESHCEMHQCRSDEFNCSSGMCIRSSWVCDGDNDCRDWSDEANCTAIYHTCEASNFQCHNGHCIPQRWACDGDADCQDGSDEDPVSCEKKCNGFHCPNGTCIPSSKHCDGLRDCPDGSDEQHCEPFCTRFMDFVCKNRQQCLFHSMVCDGIVQCRDGSDEDAAFAGCSQDPEFHKECDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFHCENGHCIPNRWKCDRENDCGDWSDEKDCGDSHVLPSPTPGPSTCLPNYFHCSSGACVMGTWVCDGYRDCADGSDEEACPSLANSTAASTPTQFGQCDRFEFECHQPKKCIPNWKRCDGHQDCQDGQDEANCPTHSTLTCTSREFKCEDGEACIVLSERCDGFLDCSDESDEKACSDELTVYKVQNLQWTADFSGDVTLTWMRPKKMPSASCVYNVYYRVVGESIWKTLETHSNKTSTVLKVLKPDTTYQVKVQVHCLNKVHNTNDFVTLRTPEGLPDAPRNLQLSLNSEEEGVILGHWAPPVHTHGLIREYIVEYSRSGSKMWASQRAASNSTEIKNLLLNALYTVRVAAVTSRGIGNWSDSKSITTIKGKVIQAPNIHIDSYDENSLSFTLTMDGDIKVNGYVVNLFWSFDAHKQEKKTLSFRGGSALSHRVSNLTAHTSYEISAWAKTDLGDSPLAFEHILTRGSSPPAPSLKAKAINQTAVECIWTGPKNVVYGIFYATSFLDLYRNPKSVTTSLHNKTVIVSKDEQYLFLVRVLIPYQGPSSDYVVVKMIPDSRLPPRHLHAVHIGKTSALIKWESPYDSPDQDLFYAIAVKDLIRKTDRSYKVRSRNSTVEYSLSKLEPGGKYHIIVQLGNMSKDSSIKITTVSLSAPDALKIITENDHVLLFWKSLALKEKQFNETRGYEIHMSDSAVNLTAYLGNTTDNFFKVSNLKMGHNYTFTVQARCLFGSQICGEPAVLLYDELSSGADAAVIQAARSTDVAAVVVPILFLILLSLGVGFAILYTKHRRLQSSFSAFANSHYSSRLGSAIFSSGDDLGEDDEDAPMITGFSDDVPMVIA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DSP1-1", "uniprot_id": "SORL_RAT", "id": "P0DSP1-1", "name": "Sortilin-related receptor", "aln": "--------------------------------MATRSSRRESRLPFLFTLVALLPPG-----------ALGGGW---------TQRLHGGGAPLPQDRGFFVVQGDPHELRLGTHGDAWG--ASPAARKPLRTRRS----------------------------------------------------------------------------------------------AALQPQPIQVYGQVSLNDSHNQMVVHWAGE------------------------KSNVIVALARDSLALTRPKS--SDVYVSYDYGKSFNKISEKLN-FGVGNSSEAVISQFYHSPADNKRYIFVDAYARYLWITFDFGSTIHGFSIPFRAADLLLHS-KASNLLLGFDSSHPNKQLWKSDDFGQTWIMIQEHVKS--FSWGIDPYDQ-PNTIYIERHEPFGFSTVFRSTDFFQSREN---QEVILEEVRDFQLRDKYLFATKVVHLPGSQQQSSVQLWVSFGRKPMRAAQFVTKHPI-----NEYYIADASEDQVFVCVSH--SNNS--TNLYISEAEGLKFSLSLENVLYYSPGGAGSDTLVRYFANEPFADFHRVEGLQGVYIATLING------SMSEENMRSVITFDKGGTWEFLQAPAFTGYGEKINCE--LSQGCSLHLAQRLSQLLNLQLRRMPILSKESAPGLIIATGSVGKNLA-SKT-NVYISSSAGARWREALPGPHYYTWGDHGGIIMAIAQG--METNELKYSTNEGETWKTFVFSEKPVFVYGLLTEPGEKSTVFTIFGSNKESVHS-WLILQVNATDALGVPCTENDYKLWSPS-----DERGNECLLGHKTVFKRRTPHATCFNGEDFDRPVV-VSNCSCTREDYECDFGFKMSEDISLEVCVPDPEFSGKPYSPPVPCPVGSSYRRTRGYRKISGDTCSGGDVEARLEGELVPCPLAEENEFILYAMRKSIYRYDLASGATEQLPLSGLRAAVALDFDYEHNCLYWSDLALDTIQRLCLNGSTGQEVIINSGLETVEALAFEPLSQLLYWVDAGFKKIEVANPDGDFRLTIVNSSVLDR--PRALVLVPQEGVMFWTDWGDLKPGIYRSNMDGSAAYRLVSEDVKWPNGISVDGHWIYWTDAYLDCIERITFSGQQRSVILDNLPHPYAIAVFKNEIYWDDWSQLSIFRASKYSRSQVETLASQLTGLMDMKIFYKGKNAGSNACIPQPCSLLCLPKANNSKSCRCPEGVASSVLPSGYLMCDCPQGYERKNNTCVKEENTCLRNQYHCSNGNCINSIWWCDFDNDCGDMSDERNCPTTICDADTQFRCQESGTCIPLSYKCDLEDDCGDNSDESHCEMHQCRSDEFNCSSGMCIRSSWVCDGDNDCRDWSDEANCTAIYHTCEASNFQCHNGHCIPQRWACDGDADCQDGSDEDPISCEKKCNGFHCPNGTCIPSSKHCDGLRDCPDGSDEQHCEPFCTRFMDFVCKNRQQCLFHSMVCDGIIQCRDGSDEDATFAGCSQDPEFHKECDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFHCENGRCIPNRWKCDRENDCGDWSDEKDCGDSHIFPSPTPGPSTCLPNYFRCSSGACVMGTWVCDGYRDCADGSDEEACPSLANSTAASTPTQLGQCDRFEFECRQPKKCIPNWKRCDGHQDCQDGQDEANCPTHSTLTCMSREFKCEDGEACIVLSERCDGFLDCSDESDEKACSDELTVYKVQNLQWIADFSGDVTLTWTRPKKMPSASCVYNVYYRVVGESIWKTLETHSNKTSTVLKVLKPDTTYQVKVQVHCLSKVHNTNDFVTLRTPEGLPDAPRNLQLSLNSEEEGVILGHWAPPVHTHGLIREYIVEYSRSGSKMWASQRAASNSTEIKNLLLNALYTVRVAAVTSRGIGNWSDSKSITTTKGKVIQAPNIHIDSYDENSLSFTLTMDGDIKVNGYVVNLFWSFDAHKQEKKTLNFRGGSSLSHKVSNLTAHTSYEVSAWAKTDLGDSPLAFEHILTRGISPPAPSLKAKAINQTAVECIWTGPKNVVYGIFYATSFLDLYRNPKSLTTSLHNKTVIVSKDEQYLFLVRVLIPYQGPSSDYVVVKMIPDSRLPPRHLHAVQIGKTSAVIKWESPYDSPDQDLFYAIAVKDLIRKTDRSYKVRSRNSTVEYSLSKLEPGGKYHIIVQLGNMSKDSSIKITTVSLSAPDALKIITENDHVLLFWKSLALKEKQFNETRGYEIHMFDSAVNLTAYLGNTTDNFFKVSNLKMGHNYTFTVQARCLFGSQICGEPAVLLYDELSSGGDATVVQTARSTDVAAVVVPILFLILLSLGVGFAVLYTKHRRLQSSFTAFANSHYSSRLGSAIFSSGDDLGEDDEDAPMITGFSDDVPMVIA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92673-1", "uniprot_id": "SORL_HUMAN", "id": "Q92673-1", "name": "Sortilin-related receptor", "aln": "--------------------------------MATRSSRRESRLPFLFTLVALLPPG-----------ALCEVW---------TQRLHGGSAPLPQDRGFLVVQGDPRELRLWARGDARG--ASRADEKPLRRKRS----------------------------------------------------------------------------------------------AALQPEPIKVYGQVSLNDSHNQMVVHWAGE------------------------KSNVIVALARDSLALARPKS--SDVYVSYDYGKSFKKISDKLN-FGLGNRSEAVIAQFYHSPADNKRYIFADAYAQYLWITFDFCNTLQGFSIPFRAADLLLHS-KASNLLLGFDRSHPNKQLWKSDDFGQTWIMIQEHVKS--FSWGIDPYDK-PNTIYIERHEPSGYSTVFRSTDFFQSREN---QEVILEEVRDFQLRDKYMFATKVVHLLGSEQQSSVQLWVSFGRKPMRAAQFVTRHPI-----NEYYIADASEDQVFVCVSH--SNNR--TNLYISEAEGLKFSLSLENVLYYSPGGAGSDTLVRYFANEPFADFHRVEGLQGVYIATLING------SMNEENMRSVITFDKGGTWEFLQAPAFTGYGEKINCE--LSQGCSLHLAQRLSQLLNLQLRRMPILSKESAPGLIIATGSVGKNLA-SKT-NVYISSSAGARWREALPGPHYYTWGDHGGIITAIAQG--METNELKYSTNEGETWKTFIFSEKPVFVYGLLTEPGEKSTVFTIFGSNKENVHS-WLILQVNATDALGVPCTENDYKLWSPS-----DERGNECLLGHKTVFKRRTPHATCFNGEDFDRPVV-VSNCSCTREDYECDFGFKMSEDLSLEVCVPDPEFSGKSYSPPVPCPVGSTYRRTRGYRKISGDTCSGGDVEARLEGELVPCPLAEENEFILYAVRKSIYRYDLASGATEQLPLTGLRAAVALDFDYEHNCLYWSDLALDVIQRLCLNGSTGQEVIINSGLETVEALAFEPLSQLLYWVDAGFKKIEVANPDGDFRLTIVNSSVLDR--PRALVLVPQEGVMFWTDWGDLKPGIYRSNMDGSAAYHLVSEDVKWPNGISVDDQWIYWTDAYLECIERITFSGQQRSVILDNLPHPYAIAVFKNEIYWDDWSQLSIFRASKYSGSQMEILANQLTGLMDMKIFYKGKNTGSNACVPRPCSLLCLPKANNSRSCRCPEDVSSSVLPSGDLMCDCPQGYQLKNNTCVKQENTCLRNQYRCSNGNCINSIWWCDFDNDCGDMSDERNCPTTICDLDTQFRCQESGTCIPLSYKCDLEDDCGDNSDESHCEMHQCRSDEYNCSSGMCIRSSWVCDGDNDCRDWSDEANCTAIYHTCEASNFQCRNGHCIPQRWACDGDTDCQDGSDEDPVNCEKKCNGFRCPNGTCIPSSKHCDGLRDCSDGSDEQHCEPLCTHFMDFVCKNRQQCLFHSMVCDGIIQCRDGSDEDAAFAGCSQDPEFHKVCDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFRCENGHCIPNRWKCDRENDCGDWSDEKDCGDSHILPFSTPGPSTCLPNYYRCSSGTCVMDTWVCDGYRDCADGSDEEACPLLANVTAASTPTQLGRCDRFEFECHQPKTCIPNWKRCDGHQDCQDGRDEANCPTHSTLTCMSREFQCEDGEACIVLSERCDGFLDCSDESDEKACSDELTVYKVQNLQWTADFSGDVTLTWMRPKKMPSASCVYNVYYRVVGESIWKTLETHSNKTNTVLKVLKPDTTYQVKVQVQCLSKAHNTNDFVTLRTPEGLPDAPRNLQLSLPREAEGVIVGHWAPPIHTHGLIREYIVEYSRSGSKMWASQRAASNFTEIKNLLVNTLYTVRVAAVTSRGIGNWSDSKSITTIKGKVIPPPDIHIDSYGENYLSFTLTMESDIKVNGYVVNLFWAFDTHKQERRTLNFRG-SILSHKVGNLTAHTSYEISAWAKTDLGDSPLAFEHVMTRGVRPPAPSLKAKAINQTAVECTWTGPRNVVYGIFYATSFLDLYRNPKSLTTSLHNKTVIVSKDEQYLFLVRVVVPYQGPSSDYVVVKMIPDSRLPPRHLHVVHTGKTSVVIKWESPYDSPDQDLLYAVAVKDLIRKTDRSYKVKSRNSTVEYTLNKLEPGGKYHIIVQLGNMSKDSSIKITTVSLSAPDALKIITENDHVLLFWKSLALKEKHFNESRGYEIHMFDSAMNITAYLGNTTDNFFKISNLKMGHNYTFTVQARCLFGNQICGEPAILLYDELGSGADASATQAARSTDVAAVVVPILFLILLSLGVGFAILYTKHRRLQSSFTAFANSHYSSRLGSAIFSSGDDLGEDDEDAPMITGFSDDVPMVIA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PHU5-1", "uniprot_id": "SORT_MOUSE", "id": "Q6PHU5-1", "name": "Sortilin", "aln": "---------------------------MERPRGAADGLLRWP--LGLLLLLQLLPPA-----------AVGQDR---------LDAPPPPAPPLLRWAGPVGVSWGLRAAAPGGPVPRAGRWRRGAPAEDQDCGRL----------------------------------------------------------------------------------------------PDFIAKLTNNTHQHVFDDLSGSVSLSWVGD------------------------STGVILVLTTFQVPLVIVSFGQSKLYRSEDYGKNFKDITNLINNTFIRTEFGMAIGPENSGKVILTAEVSGGSRGGRVFRSSDFAKNFVQTDLPFHPLTQMMYSPQNSDYLLALSTEN---GLWVSKNFGEKWEEIHKAVCL--AKWGPN------NIIFFTTHVNGSCKADLGALELWRTSDLGKTFKTIGVKIYSFGLGGRFLFASVMADK---DTTRRIHVSTDQG-DTWSMAQLPSVGQE-----QFYSILAANEDMVFMHVDE--PGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGET--------------DFTNVTSLRGVYITSTLS---------EDNSIQSMITFDQGGRWEHLRKPENS--KCDATAK--NKNECSLHIHASYSISQKLNVP-MAPLSEPNAVGIVIAHGSVGDAIS-VMVPDVYISDDGGYSWAKMLEGPHYYTILDSGGIIVAIEHS-NRPINVIKFSTDEGQCWQSYVFTQEPIYFTGLASEPGARSMNISIWGFTESFITRQWVSYTVDFKDILERNCEEDDYTTWLAHSTDP-GDYKDGCILGYKEQFLRLRKSSVCQNGRDYVVAKQ-PSVCPCSLEDFLCDFGYFRPENA--SECVEQPELKG--HELEFCLYGKEEHLTTNGYRKIPGDKCQGGMNPAREV---------------------------------------------------------------KDLKKKCTSNFLNPTKQNSKS--NSVPIILAIVGLMLVTVVAGVLIVKKYVCGG--RFLVHRYSVLQQ--HAEA------------------------------------DGVEALDSTSHA-KSGYHDDSDEDLLE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O54861-1", "uniprot_id": "SORT_RAT", "id": "O54861-1", "name": "Sortilin", "aln": "---------------------------MERPRGAADGLLRWP--LGLLLLLQLLPPA-----------AVGQDR---------LDAPPPPAPPLLRWAGPVGVSWGLRAAAPGGPVPRAGRWRRGAPAEDQDCGRL----------------------------------------------------------------------------------------------PDFIAKLTNNTHQHVFDDLSGSVSLSWVGD------------------------STGVILVLTTFQVPLVIVSFGQSKLYRSEDYGKNFKDITNLINNTFIRTEFGMAIGPENSGKVILTAEVSGGSRGGRVFRSSDFAKNFVQTDLPFHPLTQMMYSPQNSDYLLALSTEN---GLWVSKNFGEKWEEIHKAVCL--AKWGPN------NIIFFTTHVNGSCKADLGALELWRTSDLGKTFKTIGVKIYSFGLGGRFLFASVMADK---DTTRRIHVSTDQG-DTWSMAQLPSVGQE-----QFYSILAANDDMVFMHVDE--PGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGET--------------DFTNVTSLRGVYITSTLS---------EDNSIQSMITFDQGGRWEHLQKPENS--KCDATAK--NKNECSLHIHASYSISQKLNVP-MAPLSEPNAVGIVIAHGSVGDAIS-VMVPDVYISDDGGYSWAKMLEGPHYYTILDSGGIIVAIEHS-NRPINVIKFSTDEGQCWQSYVFSQEPVYFTGLASEPGARSMNISIWGFTESFLTRQWVSYTIDFKDILERNCEENDYTTWLAHSTDP-GDYKDGCILGYKEQFLRLRKSSVCQNGRDYVVAKQ-PSICPCSLEDFLCDFGYFRPENA--SECVEQPELKG--HELEFCLYGKEEHLTTNGYRKIPGDRCQGGMNPAREV---------------------------------------------------------------KDLKKKCTSNFLNPKKQNSKS--SSVPIILAIVGLMLVTVVAGVLIVKKYVCGG--RFLVHRYSVLQQ--HAEA------------------------------------DGVEALDTASHA-KSGYHDDSDEDLLE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99523-1", "uniprot_id": "SORT_HUMAN", "id": "Q99523-1", "name": "Sortilin", "aln": "---------------------------MERPWGAADGLSRWPHGLGLLLLLQLLPPS-----------TLSQDR---------LDAPPPPAAPLPRWSGPIGVSWGLRAAAAGGAFPRGGRWRRSAPGEDEECGRV----------------------------------------------------------------------------------------------RDFVAKLANNTHQHVFDDLRGSVSLSWVGD------------------------STGVILVLTTFHVPLVIMTFGQSKLYRSEDYGKNFKDITDLINNTFIRTEFGMAIGPENSGKVVLTAEVSGGSRGGRIFRSSDFAKNFVQTDLPFHPLTQMMYSPQNSDYLLALSTEN---GLWVSKNFGGKWEEIHKAVCL--AKWGSD------NTIFFTTYANGSCKADLGALELWRTSDLGKSFKTIGVKIYSFGLGGRFLFASVMADK---DTTRRIHVSTDQG-DTWSMAQLPSVGQE-----QFYSILAANDDMVFMHVDE--PGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGET--------------DFTNVTSLRGVYITSVLS---------EDNSIQTMITFDQGGRWTHLRKPENS--ECDATAK--NKNECSLHIHASYSISQKLNVP-MAPLSEPNAVGIVIAHGSVGDAIS-VMVPDVYISDDGGYSWTKMLEGPHYYTILDSGGIIVAIEHS-SRPINVIKFSTDEGQCWQTYTFTRDPIYFTGLASEPGARSMNISIWGFTESFLTSQWVSYTIDFKDILERNCEEKDYTIWLAHSTDP-EDYEDGCILGYKEQFLRLRKSSVCQNGRDYVVTKQ-PSICLCSLEDFLCDFGYYRPEND--SKCVEQPELKG--HDLEFCLYGREEHLTTNGYRKIPGDKCQGGVNPVREV---------------------------------------------------------------KDLKKKCTSNFLSPEKQNSKS--NSVPIILAIVGLMLVTVVAGVLIVKKYVCGG--RFLVHRYSVLQQ--HAEANGV---------------------------------DGVDALDTASHTNKSGYHDDSDEDLLE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NUT7-1", "uniprot_id": "SORT1_DANRE", "id": "Q6NUT7-1", "name": "Sortilin", "aln": "---------------------------MS---------------TVLCCVLVLLISV-----------ALCMDF---------EERPSSSWRSEQTMFLKSHKSRNLLSLR-DLQQPDHGKMKRSEESAQNQCESL----------------------------------------------------------------------------------------------HGYQSTLQNDTHTHNFNDLSGSVSLAWVGD------------------------GTGVLLVLTTFQVPLFIMRFGQSKLYRSEDYGKTFQDITDLINNTFIQTEFGIAIGPDNSGKVILTGDLAEG-KVTKIFRSVDFGKSFVTSELPFHPLMQITYNPKDSNILMVYSINY---DLWLSKDFGANWKKIHESVCL--VKWGID------DTIFLTTNPNGSCS-DRGTLELRKSLDYGKTFKTIGNRIYSFGLGGRFVFASIMTDS---GSTRMIHVSVDQG-ETWDMAQLPTVGHE-----QFYSILAANNDMVFMHVDE--PGDSGIGTIYISDDRGIVFSKSLERHLYTTTGGDT--------------DFTNITSLRGVYITSVLA---------EDGSVQTVITFNQGGEWRPLMKPWNG--VCDSTAK--HPSECSLHIHASYSISMKLNVP-MQPLSETNAVGLVLAHGSVGGAVS-VLSPDVYVSDDGGYTWFQALKGPHHYAILDSGGLLVAVEHNPTHPISQIKFSTDEGQCWHAHNFTDDPIYFTGLASEPGARSMNVSLWGYRDTILNQYWVSVTVDFRQLLSRDCQENDYIQWLAHSSDI-NSPTDGCVLGYKERFLRLRRDSVCWNGRDYKVTKE-PTTCPCTLTDFH-DFGFYHEENS--SVCVEQPDLIG--HSLEFCLHGRKEQLQTSGYRKIPGDHCEEGITPERKE---------------------------------------------------------------IDLSKKCVSNLLRTEQLTKEHSFNSAPIIAVVIIVLLISAVAGVIFIKKYVCGG--RFLVHRYSVLQQ--HAEANGI---------------------------------DGLDDLDTLEGG-KTHYHDDSDEDLLE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53751-1", "uniprot_id": "YN94_YEAST", "id": "P53751-1", "name": "Uncharacterized membrane glycoprotein YNR065C", "aln": "MLMTGSVGDGSEFDWEDQKTFISRDGGLTWRFVHNSSGLYATGDLGNIIVYIPYDPEEDGDFQSEFYYSLDQGRTWNEYELTNAISSVHPYKLINPTPDGSGSKFIFKGTFATTDSETNSITSLKGVEYIIDFSAAFDSRTCEEEDFEDWDLADGKCVNGAKYKYRRRKQDAQCLVKKAFKDLSLDETPCN---SCGESDYECSFEFVRDANGLCIPDYNLIAFSNICDKSKDKSVLVEPLQLIKGDECKTPMKIEPVDIPCDEIPEEGSSDREIVTTENKFDFEIKFYQYFDTVADESLVMLNSIGDAYISHDGGQTIKRFDTNGE-KIVEVVFNPYFNSSAYLFGSKGNIFSTHDRGHSFMIAKLPEARQLGMPLDFSAKAQDTFIYYGGKNCESILSPECHAVAYLTKDGGETFTEMLDNAIHCEFAGTLFEYPSNEEMVMCQVKKKSSETRSLVSSIDFFQGDN----KIIFENIIGYLSTGGYIIVAVPHED------NELRAYVTIDGTEFAEAKFPYGQDVSK--QEAFTILGSEKGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNRNTFG---------------YVDFEKVQGLEGIIITNIVSNREKVGENKEDEQLKTKITFNDGSDWNFLKPPKKDSEGKKFPCDSVSLDKCSLHLHG-YTERKDIRDT----YSSGSALGMMFGVGNVGDKLLPYEECSTFLTTDGGETWTEVKKGPHQWEYGDHGGVLVLVPEN--AETDSISYSTDFGKTWKDYKFCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGKKRADFKYSPLGSRTGCLFGHQTEFLRKTDEKCFIGNIPLSEFSRNVKNCSCTRQDFECDYNFYKASDG--TCKLVKGLSSANGADICKKEPDLIEYYDSSGYRKIPLSTCKGGLKLDAHLAPHPCPGKEKAFR-----------------------------------EKYSINTGAYALVFVTILLVIFFAAWFVYDRGIRRNGGFSRFEEIRLGDDGLIENNRTDRVVNIIVRLGLCISLITKSAFQRTKAGVAR---------------------------------FSSKLRARFGNRKGPTYSSLLQGQFSDESDGLHEDANDLSSFTSQDSN------------------------FEIEQEDAYRPEQEHTSQIDQPATSNIPDALPARSAIHKPDSTAVRNEDE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . : . : * * * . : . : : * . . : : : * : : . : . . . ::: . :: : : : . :. : .: *: * : :. .: .: *: ::. : .: : **::.* * * * . * **: : : .* .::.. *.:* : ::: . * * : : * ** : : . : * : * * * : . . . . .:* . : :: : * *::* . : : * * *: *:.: . : ***:: . * * :. : ", "identical_positions": 42, "similar_positions": 111, "identity": "1.73%" }, { "cls_id": "homologset.agr.SGD:S000005354", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K157-1", "uniprot_id": "GALM_MOUSE", "id": "Q8K157-1", "name": "Galactose mutarotase", "aln": "-MVSVTRTVFG-----ELPSGGGTVEKFQLR-SDQLSVDIISWGCTITALQVKDRQGKASDVVLGFAELEGYLQ-KQPYFGAVVGRVANRIAKGRFTIGGKEYHLPV-NRE-PNSLHGGFTGFDKVLWTPQVLT-NGVQFFRVSPDGEEG------YPGELKVWVTYTLDGGE----LVINYRAQASQTTPVNLTNHSYFNLAGQGS--PNIYDHEVTIAADAYLPVDETL-IPTGVIAPVEGTAFDLRKPVELGTHLQDYH---IHGFDHNFCLKES---KEKKFCARVRHAASGRILEVYTTQPGVQFYTGNFLDG------TLKGKNGAVYPKHSGLCLETQNWPDSVNQPQFP-PALLRPGEEYNHTTWFKFSVA--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66HG4-1", "uniprot_id": "GALM_RAT", "id": "Q66HG4-1", "name": "Galactose mutarotase", "aln": "-MVSVTRTVFG-----ELPSGGGAVEKFQLR-SDQLNVDIISWGCTITALQVKDRQGKASDVVLGFAELEGYLQ-KQPYFGAVVGRVANRIAKGRFTVDGKEYHLPI-NRE-PNSLHGGFRGFDKVLWTPQVLS-NGVQFSRVSPDGEEG------YPGELKVWVTYTLDGGE----LVVNYRAQASQTTPVNLTNHSYFNLAGQGS--PDIYDHEVTIAADAYLPVDETL-IPTGVIAPVEGTAFDLRKPVELGKHLQSYH---IHGFDHNFCLKES---KEKKFCARVHHAASGRILEVYTTQPGVQFYTGNFLDG------TLKGKSGEVYPKHSGFCLETQNWPDAVNQPQFP-PILLRPGEEYNHTTWFKFSVA--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96C23-1", "uniprot_id": "GALM_HUMAN", "id": "Q96C23-1", "name": "Galactose mutarotase", "aln": "-MASVTRAVFG-----ELPSGGGTVEKFQLQ-SDLLRVDIISWGCTITALEVKDRQGRASDVVLGFAELEGYLQ-KQPYFGAVIGRVANRIAKGTFKVDGKEYHLAI-NKE-PNSLHGGVRGFDKVLWTPRVLS-NGVQFSRISPDGEEG------YPGELKVWVTYTLDGGE----LIVNYRAQASQATPVNLTNHSYFNLAGQAS--PNINDHEVTIEADTYLPVDETL-IPTGEVAPVQGTAFDLRKPVELGKHLQDFH---LNGFDHNFCLKGS---KEKHFCARVHHAASGRVLEVYTTQPGVQFYTGNFLDG------TLKGKNGAVYPKHSGFCLETQNWPDAVNQPRFP-PVLLRPGEEYDHTTWFKFSVA--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKF7-1", "uniprot_id": "Q9VKF7_DROME", "id": "Q9VKF7-1", "name": "Aldose 1-epimerase", "aln": "MSITVEERNFG-LATNPLTEARQMVHSYTLKNTKGMSVTVIQLGATIQSINFPDGSKKVEDVCLGFDDIAGYVTNKAAYMGGTLGRVANRVASGGFTLDETTVNLTR-NVEGQFHLHGGFLGFDSVIWEVVQKTPQGVVFRHESQHGHEG------YPGILTCLITYRLDNEDR---LSISFEATTDRQTIVNLSNHAYFNLAGHNAGPKGLAEHTVEIASSEIVETDDRQ-IPTGELTLVDNTAYDLRSPVVLGDRLKQFENCPIQGFDNCYVVNGGQLLRSTVKVAKIVHPPSGRALEVWTNQPGIQFYTANNITK-------ITGKKGLFYVKHGALCVQTVKFPDAINHQNFP-SINLNPNETYRHEVVYWFKVEKTCRCCYKK-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VP02-1", "uniprot_id": "Q9VP02_DROME", "id": "Q9VP02-1", "name": "Aldose 1-epimerase", "aln": "MSITLEEEIFG-LAVNPFTKSPEMVRRYTLKNSKGMTVSVIQLGAIIQSVCLPDAYKKVDDVCLGFDDIASYLANKGAYIGGTLGRVANRVANGEYTFNDTKVSVTK-NIQDKFQLHGGFIGFDSVIWEVVQKSAEGVIFRHVSPHGHEG------YPGKLTCLITYQLDNENR---LWVRYEATTDRSTMVNLSSHAYFNLAGHGSGAKGLSEHTVEIASDQIVDTDELQ-IPTGKLVDVKDTVFDLRLPVLMRDRLMQFENRQIKGYDNCFVVNGGRVQKSVAKVAKIVHPPSCRVLEVWTDQPGMQFYTANNLTS-------IVGKNCTKYEKHGSFCVETEKFPDAMNHPEFP-SISLEPNEKYRHDVLYWFKVEESWKCCCNNDP---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VY83-1", "uniprot_id": "Q9VY83_DROME", "id": "Q9VY83-1", "name": "Galactose mutarotase", "aln": "-MVKVVEDIFG-IATNPFTKQAQVIRRYTMTNTNRLSVAIIQLGATIQSIQVPDAYHQLSDVVLGFDDVAGYTKYRNYHFGCTIGRVSDVVGNGEFIMDERRVVVSK-NLGQKHQTNGGFVGFDQVIWDLEMKRPDGVTLRHISPDGHEG------YPGTLKVLLHFTINDDNR---FFIQIEATTNQTTPVNISNHIIFNLAGQSTGIKGIFDHQINIEAIETMETSNGDGLPTGRFKNVNDSVYDIRLPVFMGDRVRQFEKKPVKGYDVCFALDKEFDAIRTRYVGRFLHPDSGRFMEIFSNQPCVKFTTGNCFPQEPLGEPPILGKKCTRYWQHCGFSLQLLNYPDAVNQPDFP-RIFINPGEHYFHETIYHFGVQESWKCCADPEELEALGEEPLRKPKAV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VRU1-1", "uniprot_id": "Q9VRU1_DROME", "id": "Q9VRU1-1", "name": "Aldose 1-epimerase", "aln": "-MVNVTEDVFANGAVNPFTKSKDTIKRFTLTNGAGMSVQLITRGATITSIKTPDASGQIDDVTLGFDDLAGYQSERNPYFGATIGRVCNRIANGSFYLDGKLVQVSK-NRDNKFQLHGGFVGFDKAHWEVVEVRVDGVTLSHTNPDGHEG------YPGKVTATASFTLSEDNC---LHVQMSALADKTTPVNLTNHSYFNLAGHKSGANGLYEHTIEINAYGITETDQSS-IPTGRITPVEGTGFDLRVSSNLGERLKALQ--PARGYDDNFCVTFS-PPQPLAKVARATHPPSGRWLEVVSNQPGVQFYTSNFMPDVERGESPIPGKDGAAYAKHCAFCLETQKFPDSVNHSNFP-STILRPGESYQHEVIYKFGVSH-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53757-1", "uniprot_id": "YN9A_YEAST", "id": "P53757-1", "name": "Uncharacterized isomerase YNR071C", "aln": "MSNSNGDNKYG---------------VITIGDEKKFQATIAPLGATLVDLKVNGQS-----VVQGYSNVQDYLT-DGNMMGATVGRYANRIAKGVFSLDDGPHKLTVNNCGNTNHSSISSLNLKQYKASPVENPSKGVYVVEFKLLDDHTQPNPNEFPGDLEVTVKYTLNVAEMTLDMEYQAQLVRGDATPINMTNHSYFNLNKVKS-EKSIRGTEVKVCSNKSLEVTEGALLPTGKIIERNIATFDSTKPTVLHEDTPVFDCTFIIDANKDLKTTDSVSVNKLVPVFKAYHPESHIKFEVSTTEPTVHLYTGDNLCG--------------KFVPRSGFAVQQGRYVDAINRDEWRGCVLLKRGEVYTSKTQYKFDI---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : : . : *. : : . * *: :: .* :* .:** .: :..* : .. :. * . .:.. .** . . . ... :** : : :. : : . * :*::.* *** : .: : : : . : :*** . . : :* . : . . : : *. * :*: : :* ::: *.: : : : .:.:: .: *::*: : :. .* * . : * : ", "identical_positions": 33, "similar_positions": 101, "identity": "8.15%" }, { "cls_id": "homologset.agr.SGD:S000005355", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIF3-1", "uniprot_id": "SL2A8_MOUSE", "id": "Q9JIF3-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPE--DPQETQPLLRPPEARTPRG---------------------------------------------------------------------------------------------------------------------------------------------------RRVFLASFAAALGPLSFGFALGYSSPAIPSLRRT--------APPALRLGDNAASWFGAVVTLGAAAGGILGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARD-VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAGWVLE-------WRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWG-SEEGWE--------EPPVGAE---HQGFQLALLRRPGIYKP-LIIGISLMVFQQLSGVNAIMFYANSIFEEAKFK--DSS-LASVTVGIIQVLFTAVAALIMDRAGRRLLLALSGVIMVFSMSAFGTYFKLTQS--LPSNSSHVG----------------------------------------------------------------LVPIAAEPVDVQVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWFMAFLVTKEFSSVMEMLRPYGAFWLTAAFCALSVLFTLTVVPETKGRTLEQVTAHFEGR--------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JJZ1-1", "uniprot_id": "SL2A8_RAT", "id": "Q9JJZ1-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPE--DPQETQPLLRSPGARAPGG---------------------------------------------------------------------------------------------------------------------------------------------------RRVFLATFAAALGPLSFGFALGYSSPAIPSLRRT--------APPALRLGDTAASWFGAVVTLGAAAGGVLGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARD-VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAGWVLE-------WRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWG-SEEGWE--------EPPVGAE---HQGFQLAMLRRPGVHKP-LIIGICLMVFQQLSGVNAIMFYANTIFEEAKFK--DSS-LASVTVGIIQVLFTAVAALIMDRAGRKLLLALSGVIMVFSMSAFGTYFKLTQS--GPSNSSHVGL---------------------------------------------------------------LVPISAEPADVHLGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHIKGVATGVCVLTNWFMAFLVTKEFNSIMEILRPYGAFWLTAAFCILSVLFTLTFVPETKGRTLEQITAHFEGR--------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LPG5-1", "uniprot_id": "A0ABK0LPG5_RAT", "id": "A0ABK0LPG5-1", "name": "Solute carrier family 2, facilitated glucose transporter member 6", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQEPLLRAEGLDYDTFPEAPASPEEKARAGAL-----------------------------------------------------------------------------------------------------------------------------------------------QNRRVFLATFAAVLGNFSFGYALVYTSPVIPALKRS--------SDPALRLDKIQASWFGSVFTLGAAAGGLSAMLLNDLLGRKLSIMFSAVPSAIGYALMAGARG-LWMLLLGRMLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP-------WRWLAVAGEGPVLVMILLLSFMPNSPRFLLSKSRDEEALQALIWLRADSEVHWEFE----QIQDNVRRQ---SSRVSWAEAWEPRVYRP-ILITVLMRFLQQLTGITPILVYLQTIFDSTSVV--LPSQQDAAIVGAVRLLSVLIAAVTMDLAGRKVLLYVSASIMFVANLTLGLYVQLVPRTLTPNSTVEIVT---------------------------------------------------------------LGGTEQPPAAAFNYLTLIPLLATMLFIMGYAMGWGPITWLLMSEVLPLRARGVASGLCVLVSWLTAFVLTKYF------LLAVVPFFFFSAICLLSLLFTGCCVPETRGRSLEQIEAFFHTRRMSFRP--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VU17-1", "uniprot_id": "Q9VU17_DROME", "id": "Q9VU17-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTASSSNSSGEEANKKSGSNNEESSHLLESAENGAKYGSRQPVKIVKASDNGRTSSTPHDQENLLGNMVHTSTSNNS-----------------------------------------------------------------------------------------------------------------------------------------------QKWPQYVAALAAAGGAFAAGTVLGWTSPAETEIVDRG-------EGYDFPVDKDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVN-VSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAGVK-------IFWLSIICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRETKAN---KVN-VWAALNRPVTRKA-LAISMGLMFFQQVCGINAVIFYASRIFLEANTG--IEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQ----------------------------------------------------------------------------------DAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNRSTPQAIPAEK---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JQU1-1", "uniprot_id": "A8JQU1_DROME", "id": "A8JQU1-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSEKVVRAMARWWQTVSQEDGD----------------SRNPITYDLLQENQSKTSKTRQYVAAMIICLGAVAAGTA-----------------------------------------------------------------------------------------------------------------------------------------------LSWTSPVFPQISAGNESSFNSTTGGISNSTSNEND-------------IRLTDSQKTLVGSMLPFGALFGALPSGYIADRIGRRYTAMVMDIPFILAWITLSFANS-VGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGILFIYVVGALVS-------WKTLSLLCLIIPILLLVGLFIVPETPVYLLKNGKRSEANRALKWLWG-DYCNTSNAIQAIQNDLDQTGV---DAS-VKDLFSNRASRNG-MVISVLLMVFQQFSGINAVIFFMNEIFESSST---LNPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLIFSSTIMTVCLAMLGAYNTINR-----------------------------------------------------------------------------------HTDLSQSIGWLPLLCIVLFIVSFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSLVTWLFGVLNAG-GADVPFWFFSAWMGVATAYVAIALQETKGKSASQIQSWLSGR--------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8MKK4-1", "uniprot_id": "TRE12_DROME", "id": "Q8MKK4-1", "name": "Trehalose transporter 1-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKILMRADTHVSFSVP-----ADGLKAN-----------------------------------------------------------------------------------------------------------------------------------------------FTFSQVLAALSVSLCSLVVGFVSAYTSPALVSMTDR--------TITSFEVTKDAGSWVGGIMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVN-VIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAGSFMN-------WSMLAFLGAALPVPFLILMIIIPETPRWFVNRGQEERARKALKWLRGKEADVEPELKELMQSQADADRQ---ATQNTCLELFKRNNLKP-LSISLGLMFFQQFSGINAVIFYTVQIFKDAGST--IDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSILGGFFYCKA-----------------------------------------------------------------------------------HGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGRVP-MSSVVNIKPFPFNM---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8N1-1", "uniprot_id": "TRE11_DROME", "id": "A1Z8N1-1", "name": "Trehalose transporter 1", "aln": "MSGRDNRGAGGGGGGHQPLSNAMGKLKEKLTRVGDELGYHRVESNLSTSNTATSLDTILPEDPFLFPQVSPQRHPQNTVRTQRLLEDEPPLSFRPLLEDDDINEPPTQQQQRTPLRASGSLELTPLPPPPTSLEIREHRDRQQRGAQGDELQRSKQSLKGSRVSFERRDTGNSNTNSNKAAESSDEDSFEEKRTGFQQQKATSVDHKGILKDLKHILANDNRRQFQAKKHVSLDVKGTRFLQDLLKESSSEEEFHKTRREFQGRKHQSLDPRVTFKLDKVLQGSSTDSDEEGEDAEHKRLIHRPKDITKPVIIDLKDLESESDEDFLTSRQHFQQQRSISTDSRKSRRLYEMDEMDNKRGENIRHAVPFVRQITEDGKPKLEVYRPTTNPIYIWTQVLAALSVSLGSLVVGFVSAYTSPALVSMTDR--------NITSFEVTQDAGSWVGGIMPLAGLAGGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVN-VAMVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCFVAGSFMN-------WSMLAFLGAALPVPFLILMFLIPETPRWFVGRGLEERARKALKWLRGKEADVEPELKGLMRSQADADRQ---ASRNTMLELLKLNNLKP-LSISLGLMFFQQFSGINAVIFYTVQIFKDAGST--IDGNLCTIIVGIVNFLATFIGIVLIDRAGRKILLYVSDIAMVLTLFVLGGFFYCKT-----------------------------------------------------------------------------------YGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIYVPETQGKTLEDIERKMMGRVRRMSSVANIKPLSFNM---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8TD20-1", "uniprot_id": "GTR12_HUMAN", "id": "Q8TD20-1", "name": "Solute carrier family 2, facilitated glucose transporter member 12", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVPVENTEGPSLLNQKGTAVETEGSGSRHPPWARG-----------------------------------------------------------------------------------------------------------------------------------------------CGMFTFLSSVTAAVSGLLVGYELGIISGALLQIKTL------------LALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLS-YTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAFANVF--HGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRLRALSDTTEELT----VIKSSLKDE---YQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGIVNLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLMPLRNDVDKRGETTSASLLNAGLSHTEYQIVTDPGDVPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQISMELAKVNYVKNNICFMSHHQEELVPKQPQKRKPQEQLLECNKLCGRGQSRQLSPET", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53631-1", "uniprot_id": "HXT17_YEAST", "id": "P53631-1", "name": "Hexose transporter HXT17", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQSSTESDRDIQDGP--------------------------DADIHVAPPVEKEWSDGFDDNEVINGDNVEPPKRGLIG-----------------------------------------------------------------------------------------------------------------------------------------------YLVIYLLCYPISFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYYLSNVRMGLLVAMFSIGCAIGGLIFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHKWYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYDNTAQWRVPLGLCFLWTLIIIIGMLLVPESPRYLIECERHEEARASIAKINKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVGLT---DGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAAGMMACMVIFASIGVKCLYP------------------------------------------------------------------------------HGQDGPSSKGAGNAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSRAMSISTACNWLWQFLIGFFTPFITGSIHFYYG-YVFVGCLVAMFLYVFFFLPETIGLSLEEIQLLYEEGIKPWKSASWVPPSRRGIPSEESKTEKKDWKKFLKFSKGSD----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : . . . :. : : : **: : : . : .:: *. . . : .* ** * * : : : :* :* ::: * : : . . : : : : *. * .:.: :: . : :* :... . . : :: * : * . * :. : .:: :: .*:.::::.* : :. * .: .* :: :. :. : ** * : .:: ", "identical_positions": 24, "similar_positions": 95, "identity": "2.41%" }, { "cls_id": "homologset.agr.SGD:S000005357", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AA14-1", "uniprot_id": "D4AA14_RAT", "id": "D4AA14-1", "name": "Ferroptosis suppressor protein 1", "aln": "MGTPRPRASVPGKRADRYRIFSQPSSAKFKMGSQVSVDTGAVHVVIVGGGFGGIAAASQLQALN---VPFMLVDMKDSFHHNVAALRASVESGFAKKTFISYSVTFKDNFRQGKVIGIDLKNRMVLLEGGEALPFSHLILATGSTGPFPGKFNEVSCQQAAIQAYEDMVKQIQRSQFIVVVGGGSAGVEMAAEIKTEYPEKE------VTLIHSRVPLADKELLP--CVRQEVKEILLRKGVQLLLSERVSNLEELPRNEYREYIKVETDKGTEVATNMVIVCNGIKINSSAYRSAFESRLASNGALKVNEFLQVEGYSN--IYAIGDCADIKEPKMAYHAGLHANIAVANIVNSMKQ------RPLKAYKPGALTFLLSMGRNDGVGQISG-----FYVGRLMVRLAKSRDLLISTSWKTMRQSPP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BUE4-1", "uniprot_id": "FSP1_MOUSE", "id": "Q8BUE4-1", "name": "Ferroptosis suppressor protein 1", "aln": "------------------------------MGSQVSVDTGAVHVVIVGGGFGGIAAASQLQALN---VPFMLVDMKDSFHHNVAALRASVESGFAKKTFISYSATFKDNFRQGKVIGIDLKNRMVLLQGGEALPFSHLILATGSTGPFPGKFNEVSCQQAAIQAYEDMVKQIQRSQFIVVVGGGSAGVEMAAEIKTEYPEKE------VTLIHSRVPLADKELLP--CVRQEVKEILLRKGVQLLLSERVSNLEELPRNEYREYIKVETDKGTEVATNMVIVCNGIKINSSAYRSAFESRLASNGALKVNEFLQVEGYSN--IYAIGDCADTKEPKMAYHAGLHANVAVANIVNSMKQ------RPLKAYKPGALTFLLSMGRNDGVGQISG-----FYVGRLMVRLAKSRDLLISTSWKTMRQSPP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BRQ8-1", "uniprot_id": "FSP1_HUMAN", "id": "Q9BRQ8-1", "name": "Ferroptosis suppressor protein 1", "aln": "------------------------------MGSQVSVESGALHVVIVGGGFGGIAAASQLQALN---VPFMLVDMKDSFHHNVAALRASVETGFAKKTFISYSVTFKDNFRQGLVVGIDLKNQMVLLQGGEALPFSHLILATGSTGPFPGKFNEVSSQQAAIQAYEDMVRQVQRSRFIVVVGGGSAGVEMAAEIKTEYPEKE------VTLIHSQVALADKELLP--SVRQEVKEILLRKGVQLLLSERVSNLEELPLNEYREYIKVQTDKGTEVATNLVILCTGIKINSSAYRKAFESRLASSGALRVNEHLQVEGHSN--VYAIGDCADVRTPKMAYLAGLHANIAVANIVNSVKQ------RPLQAYKPGALTFLLSMGRNDGVGQISG-----FYVGRLMVRLTKSRDLFVSTSWKTMRQSPP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FFC4-1", "uniprot_id": "E7FFC4_DANRE", "id": "E7FFC4-1", "name": "Ferroptosis suppressor protein 1", "aln": "------------------------------MGGQVSVDE-SVHVVIVGGGFGGIAAAQHLKHYG---VPFMLIDVLDAFHHNVAALRASVQTGFARKTFIPYKETFGLNFLQGRVIRIDTETQTVVLDNGKEVRYSHLILCTGTTGSFPSKHNSVDTYKSAIQKYEDFFHVIKEANAIVVVGGGTTGVEMAAEIKTEFHDKK------VVLIHPREEVADPELLP--CVKEQAKQVLLEKGVELLLGQKVSNLEELELNVCRSGMVVKTNKNEQVTTDLVICCTGSKINSEAYRSSMSSCLAENGALKVNKHLQVEGFDN--VYAVGDCANLSEPKMAYHAGLHAGVAATNIINSLSG------KALTSYKTGNVTMLIAMGKDAGVGQFNG-----YKLPRFLVTKGKSEGLLLWKSWREMGQKAPN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P52923-1", "uniprot_id": "AIF1_YEAST", "id": "P52923-1", "name": "Apoptosis-inducing factor 1", "aln": "------------------------------------MTINTKNIVVVGAGVFGVSVANHLYRELGGTYAIKLVTASNYVYFLPSAVRLTVSKDYT-KSILPLKNVLDSGIEVIKDTAASFDDKEVVLGSDRAIKFDILVLATGSKWADP-IGSTYTFGDNYKEYFEREASRISDADHILFLGGGFVNCELAGELLFKYLEEIRSGKKRISIIHNSDKLLPDSGLYNDTLRKNVTDYLSKNGITLYLNTVGASLDTSPK-------RIFLGEGSSKYIDADLIYRGVGISPNVPVNSISDLCDKKGFIQVEKNFRVKAVEAGNVFAIGDVTNFRYHGLVKRD-NWVDVLTRNVISSLQEGTEASLVDADCLETGHAPSGVSLGPNAGFGQFPLPLLGTINIPSFLISRAKSKNLFSDKMEPLFKK----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ::*:**.*. *::.*.:* .: *: : .:. :*:* :*...:: *:::. . .: .: . . : *:* ... : :. *:*.**:. . * . . : :* :. : *:.:*** .. *:*.*: :: :: : :** : . * ::::..: * .:*: * *. :.*: : .:. . : : * *.... .::.. ..* ::*:: ::*:. . ::*:** :: :. ..: . *::.*:. . :.* . :::* : *.**: : ::: **..*: . : : ", "identical_positions": 53, "similar_positions": 151, "identity": "12.38%" }, { "cls_id": "homologset.agr.SGD:S000005362", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91VH1-1", "uniprot_id": "PAQR1_MOUSE", "id": "Q91VH1-1", "name": "Adiponectin receptor protein 1", "aln": "------MSSHKGSAGAQGNG-----------------------------------------------------------APSGNREADTVELAELGPLLEEKGKRAASSPAKAEEDQACPVPQEEEEEV----RVLTLPLQAHHAMEKMEEFVYKVWEGRWRVIPYDVLPDWLKDNDYLLHGHRPPMPSFRACFKSIFRIHTETGNIWTHLLGFVLFLFLGILTMLRPNMYFMAPLQEKVVFGMFFLGAVLCLSFSWLFHTVYCHSEKVSRTFSKLDYSGIALLIMGSFVPWLYYSFYCSPQPRLIYLSIVCVLGISAIIVAQWDRFATPKHRQTRAGVFLGLGLSGVVPTMHFTIAEGFVKATTVGQMGWFFLMAVMYITGAGLYAARIPERFFPGKFDIWFQSHQIFHVLVVAAAFVHFYGVSNLQEFRYGLEGGCTDDSLL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V6I6-1", "uniprot_id": "G3V6I6_RAT", "id": "G3V6I6-1", "name": "", "aln": "------MSSHKGSAVAQGNG-----------------------------------------------------------APSSNRAADTVELAELGPLLEEKGKRAATSPAKAEEEQACPVPQEEEEEV----RVLTLPLQAHHAMEKMEEFVYKVWEGRWRVIPYDVLPDWLKDNDYLLHGHRPPMPSFRACFKSIFRIHTETGNIWTHLLGFVLFLFLGILTMLRPNMYFMAPLQEKVVFGMFFLGAVLCLSFSWLFHTVYCHSEKVSRTFSKLDYSGIALLIMGSFVPWLYYSFYCSPQPRLIYLSIVCVLGISAIIVAQWDRFATPKHRQTRAGVFLGLGLSGVVPTMHFTIAEGFVKATTVGQMGWFFLMAVMYITGAGLYAARIPERFFPGKFDIWFQSHQIFHVLVVAAAFVHFYGVSNLQEFRYGLEGGCTDDSLL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96A54-1", "uniprot_id": "PAQR1_HUMAN", "id": "Q96A54-1", "name": "Adiponectin receptor protein 1", "aln": "------MSSHKGSVVAQGNG-----------------------------------------------------------APASNREADTVELAELGPLLEEKGKRVIANPPKAEEEQTCPVPQEEEEEV----RVLTLPLQAHHAMEKMEEFVYKVWEGRWRVIPYDVLPDWLKDNDYLLHGHRPPMPSFRACFKSIFRIHTETGNIWTHLLGFVLFLFLGILTMLRPNMYFMAPLQEKVVFGMFFLGAVLCLSFSWLFHTVYCHSEKVSRTFSKLDYSGIALLIMGSFVPWLYYSFYCSPQPRLIYLSIVCVLGISAIIVAQWDRFATPKHRQTRAGVFLGLGLSGVVPTMHFTIAEGFVKATTVGQMGWFFLMAVMYITGAGLYAARIPERFFPGKFDIWFQSHQIFHVLVVAAAFVHFYGVSNLQEFRYGLEGGCTDDTLL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QJJ9-1", "uniprot_id": "F1QJJ9_DANRE", "id": "F1QJJ9-1", "name": "", "aln": "------MSGQIRSASHADCR-----------------------------------------------------------VTEECHVPADVELMELGPLLEENGPMGAKG-LQSEGAGALADDEEEDEEVG---EVLTLPLQAHHAMEKMEEFVHKVWEGRWRVIPFHVLPEWLKDNDYLLHGHRPPMPSFRACFGSIFRIHTETGNIWTHLLGLILFLCLGTLTMLRPNMYFMAPLQEKVVFGMFFLGAVLCLSFSWLFHTVYCHSEKVSRTFSKLDYSGIALLIMGSFVPWLYYSFYCSPQPRLIYLTIVCVLGIAAIIVAQWDRFSTPRHRPTRAGVFMGLGLSGIVPTMHFTIEEGFVKATTVGQMGWFYLMGAMYITGAGLYAARIPERYFPGKCDIWFHSHQIFHVLVVAAAFIHFYGVSNLQEFRYGLEGGCTDDTLL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCY8-1", "uniprot_id": "ADRL_DROME", "id": "Q9VCY8-1", "name": "Adiponectin receptor protein", "aln": "MDSATNLLEQQGSAADVSGGSHPAEVEVTTQARATFGMDAEGHATGEAVTTTTATLRREGSDEDIFEQVQMILRKRRGWGPEDSLSPNDLDILEYDDELVEEDDAGCPLPSTPEDTQLIEAEMTEVLKAGVLSDEIDLGALAHNAAEQAEEFVRKVWEASWKVCHYKNLPKWLQDNDFLHRGHRPPLPSFRACFKSIFRVHTETGNIWTHLLGCIAFIGVALYFISRPSVEIQT--QEKIVFGAFFIGAIVCLGFSFAFHTLSCHSVEMGRLFSKLDYCGIALLIMGSFVPWLYYGFYCHYQPKVIYLSVVSILGILSIVVSLWDKFSEPALRPLRAGVFMSFGLSGVIPAIHYSIMEGWFSQMSRASLGWLILMGLLYILGALLYALRVPERWFPGKFDIWGQSHQIFHILVIAAAFVHYHGISEMAMYRVMYSECTVPIEPITF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12442-1", "uniprot_id": "IZH2_YEAST", "id": "Q12442-1", "name": "ADIPOR-like receptor IZH2", "aln": "----------------------------------------------------------------------------------------------MSTLLERTKSVQELKKRAAGKTSANPAEVAKAKKVLR------------------------------RLYSWDEIPEWQRDNDFILHGYVKETSSFIETFKSLFYLHNESVNIYSHLIPALGFFTVLLLDKSTIKVFATTTWLDHMVIDLFYSGAFACLILSSSFHCLKSHSLRIATLGNKLDYLGICILIVTSMVSILYYGYFEKFSLFCLFALITVSFGIACSIVSLKDKFRKREWRPYRAGLFVCFGLSSIIPIFSGLYCYSFSEIWTQIQLFWVLLGGVLYIIGAVLYGMRFPEKICPGKFDIWGHSHQLFHFLVVIAALCHLRGLLNSYELVHIKMENGIVS-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . . : :. :: :. :*.* :***:: :*: .** * *:* :*.*: **::**: : *: : .: : :::*:. *: **. ** :* ** : .** .:. .**** **.:**: *:*. ***.:: . :: :. :** . :*: *:* * ***:*: :***.::* : .: . : .: *. * . :** ** **. *.**: *** *** :***:**.**: **: * *: : ", "identical_positions": 85, "similar_positions": 89, "identity": "19.06%" }, { "cls_id": "homologset.agr.SGD:S000005363", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2TGI8-1", "uniprot_id": "ZDH22_RAT", "id": "Q2TGI8-1", "name": "Palmitoyltransferase ZDHHC22", "aln": "----MLALRLLN----VVAPAYFLCISLVTFVLQLFLFLPSMREDPTATPLFSPAVLHGALFLFLSANALGNYILVVQNSPDDLGACQGTSSQRPQRPP--------PSTHFCRVCARVTLRHDHHCFFTGNCIGSRNMRNFILFCLYTSLACLYSMVAGVA----------YISAVLSISFAHPLAFLTLLPTSISQ-FFSGAVLGSDMFVILMLY----------LWFAVGLACAGFC------------------------------------------CHQLLLILRGQTRYQVRKG--VAVRAR-PWRKNLQEVFG--KRWLLGLLVPMFNVGTESSKQQDK----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0PK84-1", "uniprot_id": "ZDH22_MOUSE", "id": "A0PK84-1", "name": "Palmitoyltransferase ZDHHC22", "aln": "----MLALRLLN----VVAPAYFLCISLVTFVLQLFLFLPSMREDPTATPLFSPAVLHGALFLFLSANALGNYVLVIQNSPDDLGTCQGTMSQRPQCPP--------PSTHFCRVCSRVTLRHDHHCFFTGNCIGSRNMRNFILFCLYTSLACLYSMVAGVA----------YISAVLSISFAHPLAFLTLLPTSISQ-FFSGAVLGSDMFVILMLY----------LWFAVGLACAGFC------------------------------------------CHQLLLILRGQTRYQVRKG--MAVRAR-PWRKNLQEVFG--KRWLLGLLVPMFNVGTESSKQQDK----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N966-1", "uniprot_id": "ZDH22_HUMAN", "id": "Q8N966-1", "name": "Palmitoyltransferase ZDHHC22", "aln": "----MLALRLLN----VVAPAYFLCISLVTFVLQLFLFLPSMREDPAAARLFSPALLHGALFLFLSANALGNYVLVIQNSPDDLGACQGASARKTPCPS--------PSTHFCRVCARVTLRHDHHCFFTGNCIGSRNMRNFVLFCLYTSLACLYSMVAGVA----------YISAVLSISFAHPLAFLTLLPTSISQ-FFSGAVLGSEMFVILMLY----------LWFAIGLACAGFC------------------------------------------CHQLLLILRGQTRHQVRKG--VAVRAR-PWRKNLQEVFG--KRWLLGLLVPMFNVGSESSKQQDK----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PSH3-1", "uniprot_id": "A0A8M1PSH3_DANRE", "id": "A0A8M1PSH3-1", "name": "Palmitoyltransferase", "aln": "MLFKMGKLKLLN----TIAPAYFYAATVVTFALHFLLFTPTIFQSSDVT-INPAMLAHISIFLFLMGNALGNYIMTIRN-PSESANETVIPVCSPDCPDRIDAHYLLNGRHFCKVCKKVILKRDHHCFFTGNCIGNRNMRYFIMFSIYTSSSCLYSLVIGVA----------YLTIEYSISFENPLTFLTLLPLSTGY-FFLGLISGLQFFLVIMLY----------IWLGIGLVSVGFC------------------------------------------CQQLLLVARGQTWCELQKG--QLSECRGTWRANLTDVFG--SHWVLGLFVPVPTVETVPGNWQVYHDHKHD----------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VG80-1", "uniprot_id": "Q9VG80_DROME", "id": "Q9VG80-1", "name": "Palmitoyltransferase", "aln": "MSPEISGFRRFLHWGPITALSIIKCITLTTLYMNSMWWPPNKSFAGFAHQALFLLLSTLATFNYVMATLTGPGLMPKQWHPKDPKDAQFLQYCK-KCEG-----YKAPRSHHCRKCDRCVKKMDHHCPWINHCVGWANHAYFTYFLLFSILGSLQGTVVLCCSFWRGIYRYYYLTHGLAHLASVQFTLLSIIMCILGMGLAIGVVIGLSMLLFIQLKTIVNNQTGIEIWIVEKAIYRRYRNADCDDEFLYPYDLGWRANLRLVFNDECQKRGDGIEWPVVEGCDQYTLTREQLAQKEEKRARTRTFKCTRPVTGRWLPIFS--QGWRVCVAAPCSDEPRISLRPNDMIKVTRFRNHWLFGERVLSEQELAGVKKRQRKGPIRGWFPRRSAVEVIEAVHEGSGDGNSETPAPAAQNGNAHSHLKQQQRNGHAKKYM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12006-1", "uniprot_id": "PFA4_YEAST", "id": "Q12006-1", "name": "Palmitoyltransferase PFA4", "aln": "-MPVKLRWPWLG------IAIPTFLISFIGYGAHYFILSN---FLSVPKQITFEFCLSMIWLSYYLAICTNPGRPLPNYKPPPDIWRNFCKKCQSYKPE---------RSHHCKTCNQCVLMMDHHCPWTMNCVGFANYPHFLRFLFWIIVTTSVLFCIQAKR--------IYFIWQQRHLPGYFFKKSELIFLTISSPLNSFVLLTITILFLRCLFNQILNGRSQIESWDMDRLESLFNSGRLTQKLIDN---------------------TWRIYPESRSFQNKKDAEEHLTKKRPRFDELVNFPYDFDLYTNALLYLGPIHLWLWPYGVPTGDGNNFPKNGISKYEANSSLEDHILSLPWPPDGGKTNTVFNHGSSTIEMRNESGEQLIRTRLPQNGRHASREKWYNDWGESLDDFGVDVDME---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. : : : : . . . * *.*: * : **** : :*:* * * * :: *: : :: . : : ::.. * : .: . : . : . :. * .* . . ", "identical_positions": 17, "similar_positions": 42, "identity": "3.91%" }, { "cls_id": "homologset.agr.SGD:S000005364", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZBP2-1", "uniprot_id": "D3ZBP2_RAT", "id": "D3ZBP2-1", "name": "Paired amphipathic helix protein Sin3a", "aln": "--------------------------------------------------------------------------------------------------------MKRRLDDQESPVYAAQQRRIPGSTEAFSHQHRVLAPAP-------PVYEAVS-ETMQSATGIQYSVAPNYQVSAVPQSSGSHG-PAIAAVHS-SHHHPAAVQPHGGQVVQSHAHPAPSVAPVQGQQ------------------------------------QFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGFNTFLPPGYKIEVQTNDM------------------------------------VNVTTPGQVHQIPTHGIQPQ----PQPPPQHPSQPSAQSAPTPAQPAPQPTPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTA----------------------------------------------------------------------------PSLQNNQPVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHT----YQKEQRNAKEAGGNYTPALTEQEVYAQVARLFKNQEDLLSEFGQFLPDAN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSVLLSKTTAEKVDSVRNDHGGTVKKPQLNNKPQRPSQNGCQIRRH-----SGTGATPPVKK------KPKLISLKESSMADASKHGVGTESLFFDKVRKALRSAEAYENFLRCLVIFN--QEVISRAELVQLVSPFLGKFPELFNWFKNFLG------------------------YKESVHLESFPKERATEGIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKE--------------------------------VLNDTWVSFPSWS-------EDSTFVSSKKTQYEEHIYR----CEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGT--SEVIHRKALQRIYA-DKAADIIDGLRKNPSIAVPIVLKRLKMKEEE------WREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLLN--EIESIYDERQEQATEENAGVPVGPHLS-LAYEDKQILEDAAALIIHHVKRQTGIQKEDKYKIKQIMHHFIPDLLFAQRGDLSDVEEE----------EEEEMDVDEATGAPKKHNG-----VGGSPPKSKLLFSNTAA--------------------------------------------------------------------------------------------------------------------QKLRGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGN-IDSSQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEVCVQVTDLYLAENNNGATGGQLSSQTSRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIELLDTEEENSDDPVEAEVWTRWS------------DYVERYMS--------------------------------SDTTSPELREHLAQ---KPVFLPRNLRR---------IRKCQRGREQQEKEG------------KEGNSKKTMENVESLDKLECRFKLN-----------------------------------SYKMVYVIKSEDYMYRRTALLRAHQSHERVSKRLHQRFQAWVDKWTKEHVPREMAAETSKWLMGEGLEGLVP------------CTTTCDTETLHFVSIKKYRVKYGTVFKAP----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60520-2", "uniprot_id": "SIN3A_MOUSE", "id": "Q60520-2", "name": "Paired amphipathic helix protein Sin3a", "aln": "--------------------------------------------------------------------------------------------------------MKRRLDDQESPVYAAQQRRIPGSTEAFSHQHRVLAPAP-------PVYEAVS-ETMQSATGIQYSVAPNYQVSAVPQSSGSHG-PAIAAVHS-SHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQ------------------------------------QFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGFNTFLPPGYKIEVQTNDM------------------------------------VNVTTPGQVHQIPTHGIQPQ----PQPPPQHPSQPSSQSAPTPAQPAPQPTAAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTA----------------------------------------------------------------------------PSLQNNQPVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHT----YQKEQRNAKEAGGNYTPALTEQEVYAQVARLFKNQEDLLSEFGQFLPDAN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSVLLSKTTAEKVDSVRNDHGGTVKKPQLNNKPQRPSQNGCQIRRH-----SGTGATPPVKK------KPKLMSLKESSMADASKHGVGTESLFFDKVRKALRSAEAYENFLRCLVIFN--QEVISRAELVQLVSPFLGKFPELFNWFKNFLG------------------------YKESVHLESFPKERATEGIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKE--------------------------------VLNDTWVSFPSWS-------EDSTFVSSKKTQYEEHIYR----CEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGT--SEVIHRKALQRIYA-DKAADIIDGLRKNPSIAVPIVLKRLKMKEEE------WREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLLN--EIESIYDERQEQATEENAGVPVGPHLS-LAYEDKQILEDAAALIIHHVKRQTGIQKEDKYKIKQIMHHFIPDLLFAQRGDLSDVEEE----------EEEEMDVDEATGAPKKHNG-----VGGSPPKSKLLFSNTAA--------------------------------------------------------------------------------------------------------------------QKLRGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGN-IDSSQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEVCVQVTDLYLAENNNGATGGQLNSQTSRSLLESAYQRKAEQLMSDENCFKLMFIQSQGQVQLTVELLDTEEENSDDPVEAERWS---------------DYVERYMS--------------------------------SDTTSPELREHLAQ---KPVFLPRNLRR---------IRKCQRGREQQEKEG------------KEGNSKKTMENVESLDKLECRFKLN-----------------------------------SYKMVYVIKSEDYMYRRTALLRAHQSHERVSKRLHQRFQAWVDKWTKEHVPREMAAETSKWLMGEGLEGLVP------------CTTTCDTETLHFVSINKYRVKYGTVFKAP----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96ST3-1", "uniprot_id": "SIN3A_HUMAN", "id": "Q96ST3-1", "name": "Paired amphipathic helix protein Sin3a", "aln": "--------------------------------------------------------------------------------------------------------MKRRLDDQESPVYAAQQRRIPGSTEAFPHQHRVLAPAP-------PVYEAVS-ETMQSATGIQYSVTPSYQVSAMPQSSGSHG-PAIAAVHS-SHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQ------------------------------------QFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGFNTFLPPGYKIEVQTNDM------------------------------------VNVTTPGQVHQIPTHGIQPQ----PQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTA----------------------------------------------------------------------------PSLQNNQPVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHT----YQKEQRNAKEAGGNYTPALTEQEVYAQVARLFKNQEDLLSEFGQFLPDAN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSVLLSKTTAEKVDSVRNDHGGTVKKPQLNNKPQRPSQNGCQIRRH-----P-TGTTPPVKK------KPKLLNLKDSSMADASKHGGGTESLFFDKVRKALRSAEAYENFLRCLVIFN--QEVISRAELVQLVSPFLGKFPELFNWFKNFLG------------------------YKESVHLETYPKERATEGIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKE--------------------------------VLNDTWVSFPSWS-------EDSTFVSSKKTQYEEHIYR----CEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGT--SEVIHRKALQRIYA-DKAADIIDGLRKNPSIAVPIVLKRLKMKEEE------WREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLLN--EIESIYDERQEQATEENAGVPVGPHLS-LAYEDKQILEDAAALIIHHVKRQTGIQKEDKYKIKQIMHHFIPDLLFAQRGDLSDVEEE----------EEEEMDVDEATGAVKKHNG-----VGGSPPKSKLLFSNTAA--------------------------------------------------------------------------------------------------------------------QKLRGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGN-IDSSQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEICVQVTDLYLAENNNGATGGQLNTQNSRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIELLDTEEENSDDPVEAERWS---------------DYVERYMN--------------------------------SDTTSPELREHLAQ---KPVFLPRNLRR---------IRKCQRGREQQEKEG------------KEGNSKKTMENVDSLDKLECRFKLN-----------------------------------SYKMVYVIKSEDYMYRRTALLRAHQSHERVSKRLHQRFQAWVDKWTKEHVPREMAAETSKWLMGEGLEGLVP------------CTTTCDTETLHFVSINKYRVKYGTVFKAP----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F0R9-1", "uniprot_id": "E7F0R9_DANRE", "id": "E7F0R9-1", "name": "Paired amphipathic helix protein Sin3a", "aln": "--------------------------------------------------------------------------------------------------------MKRRLEDQD--TVIGSQRRLPGGVDSF--QHRVLNSAS-------SLFETAAPETMQPSSSMQYSVSQTYQLS-MPQNSGGHGHTSSSAVHTGPHHHGPAVQPVG----QAHSHATPAPAPTLGQQ------------------------------------QFQRLKVEDALSYLDQVKLQFGNQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGFNTFLPPGYKIEVQTNDL------------------------------------VNVTTPGQIHHITPHGISVQNIPITQPAPHQP-QPAPPTSTAALVIPSQPTPAKISKPMQSPALTPTSQPNPSIPSYASPRSPSVQSHTPISSSTAGS----------------------------------------------------------------------------TPLQNNQPVEFNHAINYVNKIKNRFQGQPEVYKSFLEILHT----YQKEQRNAKEAGGNYTPTLTEQQVYAQVAQLFKNQEDLLSEFGQFLPDAN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSVLLSKTTAEKAEAVRIDHGGTVKRPQLNNK-QRFNQNGCQIRRH-----SGPPTTPPVKK------KQK-FAVKDPSVAEASKLGIGAESLFFEKVRKALRSSEAYDNFLRCLVIFN--QEVISRAELVQLVLPFLGKFPELFTWFKNFLG------------------------YRECAHIESFPKERATEGIAMEIDYASCKRLGSSYRALPKSFQQPRCTGRTPLCKE--------------------------------VLNDTWVSFPSWS-------EDSTFVSSKKTQYEEHIYR----CEDERFELDVVLETNLATIRVLEAVQKRISRMSAEEQAKFRLDNTIGGS--SEVIHRKAIQRIYG-DKAPDIIDGLKTNPAVSVPIVLKRLKIKEEE------WREAQRGFNKIWREQNEKYYLKSLDHQGINFKQNDTKVFRSKTLLN--EIETLYDERQEQASEDNAAVPSGPHMT-LMYEDSQILEDAAALIIHHVKRQSGIHKDDKYKIKQIIYHFIPDMLFARRGELSDVEEE----------DEEETEPDEDG--TKKHNG-----TTSS--KSKLLFSHTAASQ------------------------------------------------------------------------------------------------------------------QKLSSCDDAYNLFFVNNNWYIFLRLHYILCSRLLRIYGQAEKQIEEDTREREWERNVLGLKREKNDSPAIQLRLKEPMDIEVEDYYSAFLEMVRNLLDGN-METSQYEDQLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDDICVQVTDLYLSECANKATGGSLSTQSSRSNAETSYQRKSEQLMSDENCFKLLFQKSKGTVQLAVELLDTEEENSDGPVDTERWP---------------DYVERYLN--------------------------------TSSASPELREHLSQ---KPVFLPRNLRR---------IRKCQRGQEMQMREA------------KETAKKSSEGGDDS--KMECMFKLN-----------------------------------SYKMVYVFKSEDYMYRRTAQLRAHQSHQRVSTRLHQRFQMWLDRWRKEHVTSDMAATNHKWLMGEGQDGLLP------------CRTVCEPKILHFQNINKYKVTYSTTS-------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q62141-4", "uniprot_id": "SIN3B_MOUSE", "id": "Q62141-4", "name": "Paired amphipathic helix protein Sin3b", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHAG-------SGGSAG-----------------RGFGGSRWGRSGSGGHE------------------------------------KLP-VHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGK------------------------------------LNIQSP------------------------------------------------LSSQDNSHSHGDCGEDFKQMS-YKEDR-----GQVPLES---------------------------------------------------------------------------------------DSVEFNNAISYVNKIKTRFLDHPEIYRSFLEILHT----YQKEQLHTKGRP---FRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSLFTGNGSCEMNSGQKNE----EKSLEHNKKRSRPS--------------LLRPVSAPAKK------KMKLRGTKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFN--QELVSGSELLQLVSPFLGKFPELFAQFKSFLG------------------------VKELSFAPPMS-DRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAICKE--------------------------------VLNDTWVSFPSWS-------EDSTFVSSKKTPYEEQLHR----CEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKLRLDDCLGGT--SEVIQRRAIHRIYG-DKAPEVIESLKRNPATAVPVVLKRLKAKEEE------WREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLN--EIESVYDEHQEQHSEGRSAPSSEPHLI-FVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIRQLLHRFLPSLFFSQQCP-GTSDDS----------ADE-RDRDR-DSAEPERRR---------PTDEK------PPADASPEPP---------------------------------------------------------------------------------------------------------------KVLDDVYSLFFANNNWYFFLRLHQTLCARLLKIYRQAQKQLLEHRREQEREQLLCEGRREKAADPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGS-IDPTQYEDTLREMFTIHAYIGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEQQRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQRRGQVIMTIELLDTEEAQTEDPVEVQHLAR---------------YVEQYVG--------------------------------SEGASSSSTEGFLL---KPVFLQRNLKK---------FRR-WQCEQVRAMRG------------EAKSSWKRLMGVESACDVDCRFRLG-----------------------------------THKMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHRHFEEWHGRWLEDNVTVAAAGLVQDWLMGEEEEDMVP------------CKTLCETAHVHGLPVTRYRVQYSRRPASP----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75182-1", "uniprot_id": "SIN3B_HUMAN", "id": "O75182-1", "name": "Paired amphipathic helix protein Sin3b", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHAGGGSGGSGAGGPAG-----------------RGLSGARWGRSGSAGHE------------------------------------KLP-VHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGK------------------------------------LNIQSP------------------------------------------------LTSQENSHNHGDGAEDFKQQVPYKEDK-----PQVPLES---------------------------------------------------------------------------------------DSVEFNNAISYVNKIKTRFLDHPEIYRSFLEILHT----YQKEQLNTRGRP---FRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSLFTGNGPCEMHSVQKNEH---DKTPEHSRKRSRPS--------------LLRPVSAPAKK------KMKLRGTKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFN--QELVSGSELLQLVSPFLGKFPELFAQFKSFLG------------------------VKELSFAPPMS-DRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAICKELDHWTLLQGSWTDDYCMSKFKNTCWIPGYSAGVLNDTWVSFPSWS-------EDSTFVSSKKTPYEEQLHR----CEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDSLGGT--SEVIQRRAIYRIYG-DKAPEIIESLKKNPVTAVPVVLKRLKAKEEE------WREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLN--EIESVYDEHQEQHSEGRSAPSSEPHLI-FVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEES----------ADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPP-----------------------------------------------------------------------------------------------------------APHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGS-IDPTQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQHLAR---------------YVEQYVG--------------------------------TEGASSSPTEGFLL---KPVFLQRNLKK---------FRRRWQSEQARALRG------------EARSSWKRLVGVESACDVDCRFKLS-----------------------------------THKMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFEEWHSRWLEDNVTVEAASLVQDWLMGEEDEDMVP------------CKTLCETVHVHGLPVTRYRVQYSRRPASP----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4K765-1", "uniprot_id": "A0A0B4K765_DROME", "id": "A0A0B4K765-1", "name": "Paired amphipathic helix protein Sin3a", "aln": "-MMKRTRVDEVQFGTRPVPQTSGGVGVGVVGVTGGGPTSGGGGTATVGVNTTGVTIGTVVPSAHNATISGIGSIHHRILTPQHGGAQTIAYLPSTTPTATNLKTTTSIVDSTTAGGPVGAGAQVAVGVGSAAGGGGVVVSTGSTGTQTLQYTTSYSVASIQAGGTLKANTADGANTVQIHVTGGGAANNPASAQTVSSSSQTGTIRQRTISGTQTVATAVGNLATISQQQPVQQSPLGKAQTPPSSVVANSIPVGGTTPPQGQSGNATPRLKVEDALSYLDQVKYQYADQPQIYNNFLDIMKEFKSHCIDTPGVIERVSTLFKGHTELIYGFNMFLPPGYKIEIHSDALGCSVPVVSMPSPPGAPTSTGTVHMLTGNSSMSGAGHIAIKTTNAATLTPAAGAGAAAAAAAVAQIQSAGAVNLMTHGGASLTQTTIHALQQATPPQSQSPGGGHVHVSVTNSTAANAVVPGQPGISVSAHNVPQNYSRDRERATITPTGQVAGAAANVNASASIVVGGPPTPNSLSELSPHGGAGGGPGAGAAQHNLHHIQQAHQSILLGETGQQNQPVEFNHAITYVNKIKNRFQNQPAKYKKFLEILHD----YQREQKVMKEGSLNQGKMLTEQEVYTQVAKLFGQDEDLLREFGQFLPDATNHQSGQYMSKSASVHNDHGKRPTATLSGGAHITMSSASPAPSGSPLHLGATTLPQIDKSAHAAAIGNLSAVNTSVSIKTYNNNQQQQNHVIGSGLNATRNDILFEKDYHAGLQQQAHQRGAGVGGHHHLAGTAAGANIGRPGVGASVMVSYDKEHRNNHHVQKYVGHAPNQNLTHGHNAKKSPSYGIPSVIGSMPHISDNSLDRSSPGISYATPPLPSGPHGQHNSGSATRRPGDDSLVGHYASGAPPA------KRPKPYCRDVSFSEASSKCTISDAAFFDKVRKALRSPEVYDNFLRCLTLFN--QEIVSKTELLGLVSPFLMKFPDLLRWFTDFLGPPSGQPAGGLIDGMPLAATQRQGGGSSNSSHDRGTSHQSAAEYVQDVDLSSCKRLGASYCALPQSTVPKKCSGRTALCRE--------------------------------VLNDKWVSFPTWAS------EDSTFVTSRKTQFEETIYRNIHRTEDERFELDLVIEVNSATIRVLENLQKKMSRMSTEELSKFHLDDHLGGT--SQTIHQRAIHRIYG-DKSGEIITGMKKNPFVAVPIVLKRLKVKEEE------WREAQKTFNKQWREQNEKYYLKSLDHQAINFKPNDMKALRSKSLFN--EIETLYDERHDQ--EDDAMEPFGPHLV-LPYKDKTILDDAANLLIHHVKRQTGIQKQEKQKIKQIIRQFVPDLFFAPRQPLSDDERDDAFPFLVDDNTKMDVDSPLGRTESSTRNAKSTPSESASPARSNASTSSVTPAGIKKETDDSKATTGSFAPASSATASSATPVDDATPSTSSAAAAASAASSSTVSGTEGKPKDDPLSSHKEEGAGSTSSGVATSPRQAQDTAGAGVDVEIKLEHPADFSNPKLLPPHAHGQREDESYTLFFANNNWYLFLRLHAILCDRLHVMYERARLLAIEEER----------CRVNRRESTATALRLKPKPEIQVEDYYPTFLDMLKNVLDGN-MDSNTFEDTMREMFGIYAYISFTLDKVVSNAVRQLQYCVTERAALDCVELFATEQRRGCTGGFCRDAHKTFDREMSYQRKAESILNEENCFKVYIYKID--CRVTIELLDSEPEEVDKPAALKAQKFS-------------KYVERLANPALGGGGNTGRSDSALGNDSVVDGSDIKTEADEDTAELRYREGGIGGAGKARFLVRNKRRS--KLLEEQVRQLFEHRRNRIEQHGTAASLEPISVDSAISSNSTTGGGGSGTNNNNNNNNNNNSWGGKRLERLGAPQVGLAEQYAFNDRDEISTNISNGRCFVTSKNLKLLKYDAVRRAKKSHCRVTQAKYAHFQTYVNKWLQQHVSEQQQQNCVDWLLGKTADQINASGW--GSASKTKTVQQKDTSKTPYRIYNRYRVVQSAVSGGLMSATAPTPDGSVPAVNSAPSGSVSTVNNVQGSAAVSSTSHSMCNSSILSADSTTNTNASAQQQQHCNSAAAATTPNAEALQQVRPMES", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22579-1", "uniprot_id": "SIN3_YEAST", "id": "P22579-1", "name": "Transcriptional regulatory protein SIN3", "aln": "---------------MSQVWHNSNSQSNDVATSNDATGSNERNEKEPSLQGNKPGFVQQQQRITLPSLSALSTKEEDRRDSNGQQALTSHAAHILGYPPPHSNAMPSIATDSALKQPHEYHPRPKSSSSSPSINASLMNAGP-------APLPTVGAASFSLSRFDNPLPIKAPVHTEEPKSYNGLQEEEKATQRPQDCKEVPAGVQPADAPDPSSNHADANDDNNNNENS------------------------------HDEDADYRPLNVKDALSYLEQVKFQFSSRPDIYNLFLDIMKDFKSQAIDTPGVIERVSTLFRGYPILIQGFNTFLPQGYRIECSSNPDD----------------------------------PIRVTTPMGTTTVNNNISPSGRGTTDAQELGSFPESDGNGVQQPSNVPMVPSSVYQSEQNQDQQQSLPLLATSSGLPSIQQPEMPAHRQIPQSQSLVPQ----------------------------------------------------------------------------EDAKKNVDVEFSQAISYVNKIKTRFADQPDIYKHFLEILQT----YQREQK-------------PINEVYAQVTHLFQNAPDLLEDFKKFLPDSSASANQQVQHAQQHAQQQHEAQMHAQAQAQAQAQAQVEQQKQQQQFLYPASG----------------------------------------------------------------------------------------YYGHPSNRGIPQQNLPPIGSFSPPTNGSTVHEAYQDQQHMQPPHFMPLPSIVQHGPNMVHQGIANENPPLSDLRTSLTEQYAPSSIQHQQQHPQSISPIANTQYGDIPVRPEIDLDPSIVPVVPEPTEPIENNISLNEEVTFFEKAKRYIGNKHLYTEFLKILNLYS--QDILDLDDLVEKVDFYLGSNKELFTWFKNFVG-----------------------------YQEKTKCIENIVHEKHRLDLDLCEAFGPSYKRLPKSDTFMPCSGRDDMCWE--------------------------------VLNDEWVGHPVWAS------EDSGFIAHRKNQYEETLFK----IEEERHEYDFYIESNLRTIQCLETIVNKIENMTENEKANFKLPPGLGHT--SMTIYKKVIRKVYDKERGFEIIDALHEHPAVTAPVVLKRLKQKDEE------WRRAQREWNKVWRELEQKVFFKSLDHLGLTFKQADKKLLTTKQLIS--EISSIKVDQTNKKIHWLTPKP-KSQLD-FDFPDKNIFYDILCLADTFITHTTAYSNPDKERLKDLLKYFISLFFSISFEKIEESLYSHKQNVSESSGSDDGSSIASRKRPYQQEMSLLDILHRSRYQKLKRSNDEDGKVPQLSEPPEEEPNTIEEEELIDEEAKNPWLTG-----------------------------------------------------------------------------NLVEEANSQGIIQNRSIFNLFANTNIYIFFRHWTTIYERLLEIKQMNERVTKEINTRS-------TVTFAKDLDLLSSQLSEMGLDFVGEDAYKQVLRLSRRLINGD-LEHQWFEESLRQAYNNKAFKLYTIDKVTQSLVKHAHTLMTDAKTAEIMALFVKDRNASTTS--AKDQIIYRLQVRSHMSNTENMFRIEFDKRTLHVSIQYIALDDLTLKEPKADEDKWKYYVTSYALPHPTEGIPHEKLKIPFLERLIEFG------------------------------QDIDGTEVDEEFSPEGISVSTLKIKIQP--------------ITYQLHIENG-----------SYDVFTRKATNKYPTIANDNTQKG-------------------------------------MVSQKKELISKFLDCAVGLRNNLDEAQKLSMQKKWENLKDSIAKTSAGNQGIESETEKGKITKQEQSDNLDS------------STASVLPASITTVPQDDNIETTGNTESSDKGAKIQ----------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A8I6AD74-1", "uniprot_id": "A0A8I6AD74_RAT", "id": "A0A8I6AD74-1", "name": "", "aln": "MDTEREALQCTAYPEVQSFCQKHGLAFEAVDLRWGIPNTQATDYLTTELCLEELERCQKTSVGPAFVALLGDQYGPCPVPQRIEEKEWEALRAQLTSRPRDLELVTRHFQRDDNTIPPTYVLQPPGSGVVPGPEEATLTSVLRGGAQEAWRLGLISQEQWMCYHRSVIEWEIEHGLLNSARGDQGATVFLRDVQDLSKHILDDCCLKMVDRLADGCLDTNAQSLLSGLKGRILDAQPG-----------------ALKSHHLPWSRDLVNPKNKTHARYLKQLSEQFVAR--TNHQVLEQLRELELARQELGWLYQEIRHHLWQSTESTKVFCGHQELLAQLKQRLRQDE-----------------------------------SRTHTPLVLFGPPGIGKTSLMCKLAQQVPELLGHKTVAVLRLLGTSKLSLDARSLLRSLSFQLCLAYGLPLPPAQVLEAHSRVGHFFHILLHTVSQRN--------------------------------------------------------------------------FESLVLLLDSVDDLDSIRHTPRVSWLPLKCPPRVHLILSACSGQQVLCNLQQTLKDPSAYWEVKALSGSQGQEFIQLLLAAERRMLSPGQRDVLWASLPECG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HPGRLRLAFEEARKWASFTVPVPLATTAEEATHQFCIRLEETHGQLLVARVLGYIVSSRYGLSEAELKDVLS-LDDEVLQAVYRDWTPPSKELLRFPPLLWVRLRRDLGHCLVRRPVDGCILLAIAHRQLSQVIQVRYLSGPERAKRHGVLAEFFSGAWSQG---------------------IKKLITLPLVGKPLNLDRKVAPQPLWFSGTVANWRKLTELPFHLLHAGCLEELKQEVLG-------------------------------NMSWISCRGISGGIEDLLDDFDMCAPHMDSPEVYLVREAIQLCRPAVELRGLEKSILYTELLARLLFFATSHPAMIGQLCQQAQSWFRACPYPMLVPLAGFLQPPGGPLRATLTGCHKGITAIAWSLEEKLLVVGTQDGTMVVWDVEEQQVVHVLMGHTAEVRCVRVFAQGTLAISASKDHTLRLWSLLSGQEKATILDGGSPNPTEQQGWDLHVDEIKNVVYSTSGTKINVWDLETSKLVFCITGDASDPWVCVALLAAQGLLLALTEGGQVSLWSSAVGKLQEKHQLCSIKEETPTCAVSIQTRARLVVGFSSGSVALVCAGEDRLLEKLPEAVG--------------------------------------------------------------------------------------------------------------FLAVSEDDSLLAVGFGRCVRVFLADSQDFHRFMATDLEHEDVVETAVLGPENNLIITASRDALIQVWSLSEQGTLLSVFESAGAPASLLVLCETLVVSASWKSSSFKAWDLRSTQKPPSPTPFLDRTGLATVSHHGSYVYFPKVGDKNKVTIWDLAEGEEQDSLDTSNEVCCLEVAEQTKLLFTGLVSGIVLVFPLNSRQDVLCIPPPEARKAVNCMSVSKSEDRLAIAY-----------DNIVLVLDISPG-----------------------DLCPAIEGPTYTFYTQLPETIVRVAVLADYRVVYGMSDGSLFLYDCAQSKVFPLEAHG------SRVSCVEVSHREQLAVSGAEDALLCLWDLQ-----------------------------------ACREKFKMSYESSYCRGVRCACFSKDDKHVFTGMEDRSIIAWSALDGTLLAVQFVHAVVNRIIPTSNGFMAPTSHGYLIRERFQCPSARASQQDPLKNFKKAVWLIKTRQREDLAEAEAPQDAEPVAVEGKESKSNKHSQVCLIL--------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : **.*:. :: : .*: ::::: : : .: : . * . ::. :. . *: .:* :. ::. * : :*. : :* . .: : *: :* : : :. :. . .. :: : :: : . : : ::: . :: . :: * . . .. . . : * * *:. : :* : : : * : : * : * . : .. : : : . : : : : : . : .: * * :: . *: : . : .: : : : :. . : : *:. * :: : . .: . : : * : : :: : . . . : . .: *: . . .* : . :: . . :: . . :*: . : : . : : : : . . : : : . * . : : : . . . : . . ", "identical_positions": 30, "similar_positions": 190, "identity": "1.39%" }, { "cls_id": "homologset.agr.SGD:S000005365", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQI0-1", "uniprot_id": "D3ZQI0_RAT", "id": "D3ZQI0-1", "name": "", "aln": "MNAPPAFESFLLFEGEKKITINKDTKVPNACLFTINKEDHTLGNIIKSQLLKDPQVLFAGYKVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLISELSLLEERFRVAIKDKQEGIE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52435-1", "uniprot_id": "RPB11_HUMAN", "id": "P52435-1", "name": "DNA-directed RNA polymerase II subunit RPB11-a", "aln": "MNAPPAFESFLLFEGEKKITINKDTKVPNACLFTINKEDHTLGNIIKSQLLKDPQVLFAGYKVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLISELSLLEERFRVAIKDKQEGIE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O08740-1", "uniprot_id": "RPB11_MOUSE", "id": "O08740-1", "name": "DNA-directed RNA polymerase II subunit RPB11", "aln": "MNAPPAFESFLLFEGEKKITINKDTKVPNACLFTINKEDHTLGNIIKSQLLKDPQVLFAGYKVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLISELSLLEERFRGAIKDKQEGIE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZM3-1", "uniprot_id": "RPB1B_HUMAN", "id": "Q9GZM3-1", "name": "DNA-directed RNA polymerase II subunit RPB11-b1", "aln": "MNAPPAFESFLLFEGEK-ITINKDTKVPKACLFTINKEDHTLGNIIKSQLLKDPQVLFAGYKVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLISELSLLEERFRTCLLPLRLLP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9H1A7-1", "uniprot_id": "RPB1C_HUMAN", "id": "Q9H1A7-1", "name": "DNA-directed RNA polymerase II subunit RPB11-b2", "aln": "MNAPPAFESFLLFEGEK-ITINKDTKVPNACLFTINKEDHTLGNIIKSQLLKDPQVLFAGYKVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLISELSLLEERFRTCLLPLRLLP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJE4-1", "uniprot_id": "RPB11_DROME", "id": "Q9VJE4-1", "name": "DNA-directed RNA polymerase II subunit RPB11", "aln": "MNAPPTFESFLLYEGEKKIIKELDTKVTNAAIFTINKEDHTLGNMIRNQLLKDPNVLFAGYKVPHPLEHKFVIRIQTTADYSPQEAFMNAITDLLAELSLFEERFKDAIKEKKEGGD---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38902-1", "uniprot_id": "RPB11_YEAST", "id": "P38902-1", "name": "DNA-directed RNA polymerase II subunit RPB11", "aln": "MNAPDRFELFLLGEGESKLKIDPDTKAPNAVVITFEKEDHTLGNLIRAELLNDRKVLFAAYKVEHPFFARFKLRIQTTEGYDPKDALKNACNSIINKLGALKTNFETEWNLQTLAADDAF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** ** *** ***. : : ***..:* ::*::********:*: :**:* :****.*** **: :: :*:*** .*.*::*: ** ..:: :*. :: .*. ", "identical_positions": 49, "similar_positions": 36, "identity": "40.83%" }, { "cls_id": "homologset.agr.SGD:S000005366", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IM78-1", "uniprot_id": "TOP1M_RAT", "id": "Q6IM78-1", "name": "DNA topoisomerase I, mitochondrial", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLLLWLRALCRRFQHVP---------------------RRVPSRQVS---RGSKASRAGWG-ETSKSSVKWKQLEHKGPCFAPAYEPLPDGVRFFYDGKPVRLSLAAEEVATFYGKMLHLECTTKEVFRRNFFSDWQKEMTAEERKL----ITHLDKCDFSEIHRHFMERAEARRTLPREQKQKLKEEAEKLQQEFGYCILDGHREKIGNFKTEPPGLFRGRGDHPKMGMLKRRVMPEDVVINCSRDSKIPEPPAGHQWKEVRSDNTVMWLAAWVENIQNSFKYIILNPSSKPKGEMDWQKYEVARRLKGVVDKIRAQYQADWKSPEMKKRQLAVALYFIDKLALRTGNEKEEGETADTVGCCSLRVEHVRLHTPADGQEHVVELDFLGKDSIRYKNHVTVEKLVFQNLQHFMED-KDPRDDLFDALTTSSLNKHLQDLMEGLTAKVFRTYNASITLQEQLRVLTRAEDSLTCKVLAYNRANRAVAVLCNHQRAIPKTFEESMQTLQKKIET-------------------------------------------------------------------KKAQVAEAQVELQKAETDLRMRGDSKSKSF-----------LQKQQRLLK-LEEQLARLCTKATDKEENKQVALGTAKLNYLDPRISIAWCKRFGVPVEKIYNKTQRERFAWAFNQAGEDFEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4U6-1", "uniprot_id": "TOP1M_MOUSE", "id": "Q8R4U6-1", "name": "DNA topoisomerase I, mitochondrial", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLLLWLRALCRRFQHVP---------------------CRVPSCQVS---RVAKANRAGWE-ETSKSSVKWRQLEHKGPYFTPAYEPLPDGVHFLYDGKPLKLSLAAEEVATFYGKMLHLECTSKEVFRRNFFSDWRKEMTPEERRL----ITHLDKCDFTEIHKHFLERAEARRTLPREQKQKLKEEAEKLQQEFGYCVLDGHREKIGNFKTEPPGLFRGRGDHPKMGMLKRRVMPEDVVINCSRDSKIPEPPAGHQWKEVRSDNTVMWLAAWVEHIQNSFKYVILNPSSKPKGEMDWQKYEVARRLKGVVDKIRAQYQADWKSPEMKKRQLAVALYFIDKLALRTGNEKEEGETADTVGCCSLRVEHIRLHAPAGGQEHVVELDFLGKDSIRYKNHVTVEKLVFQNLQHFMED-KDPRDDLFDALTTSSLNKHLQDLMEGLTAKVFRTYNASVTLQEQLRVLTRAEDSVTCKVLAYNRANRAVAVLCNHQRAVPKTFEKSMQTLQKKIET-------------------------------------------------------------------KKAQVAEAQVELQKAETDLRMRGDSKPKSF-----------LQKQRRLLK-LEEQLARLCAKATDKEENKQVALGTAKLNYLDPRISIAWCKRFGVPVEKIYNKTQRERFAWAFNQAGEDFEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969P6-1", "uniprot_id": "TOP1M_HUMAN", "id": "Q969P6-1", "name": "DNA topoisomerase I, mitochondrial", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MR----------------------------------------------------------------------------------------------------------------------------------------VVRLLRLRAALTLLGEVP---------------------RRPASRGVPGSRRTQKGSGARWEKEKHEDGVKWRQLEHKGPYFAPPYEPLPDGVRFFYEGRPVRLSVAAEEVATFYGRMLDHEYTTKEVFRKNFFNDWRKEMAVEEREV----IKSLDKCDFTEIHRYFVDKAAARKVLSREEKQKLKEEAEKLQQEFGYCILDGHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRITPEDVVINCSRDSKIPEPPAGHQWKEVRSDNTVTWLAAWTESVQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCIRYYNRVPVEKPVYKNLQLFMEN-KDPRDDLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTKIQA-------------------------------------------------------------------KKEQVAEARAELRRARAEHKAQGDGKSRSV-----------LEKKRRLLEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRERFAWALAMAGEDFEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04750-1", "uniprot_id": "TOP1_MOUSE", "id": "Q04750-1", "name": "DNA topoisomerase 1", "aln": "------------------------------MSGDHLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHK---------------------------KDKDKDREKSKHSN------------------------SEHKDS-EKKHKEKEKTKHKDGSSEKHKDKHKDRDKERRKEEKIRAAGDAKIKKEKENGFSSPPRIKDEPEDDGYFAPPKEDIKPLKRLRDEDDADYKPK----------------------------------------------------------------------------------------------------------------------------------------KIKTEDIKKEKKRKSEEE-----EDGKLKKPKNKDKDKKVAEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPESVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNT----ITNLSKCDFTQMSQYFKAQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMEN-KQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDA-------------------------------------------------------------------KKDQLADARRDLKSAKADAKVMKDAKTKKV-----------VESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WUL0-1", "uniprot_id": "TOP1_RAT", "id": "Q9WUL0-1", "name": "DNA topoisomerase 1", "aln": "------------------------------MSGDHLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHK---------------------------KDKDKDREKSKHSN------------------------SEHKDS-EKKHKEKEKTKHKDGSSDKHKDKHKDRDKEKRKEEKIRAAGDAKIKKEKENGFSSPPRIKDEPEDDGYFAPPKEDIKPLKRPRDEDDADYKPK----------------------------------------------------------------------------------------------------------------------------------------KIKTEDIKKEKKRKLEEE-----EDGKLKKPKNKDKDKKVAEPDNKKKKAKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPEGVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNT----ITNLSKCDFTQMSQYFKAQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMEN-KQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDA-------------------------------------------------------------------KKDQLADARKDLKSAKADAKVMKDAKTKKV-----------VESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11387-1", "uniprot_id": "TOP1_HUMAN", "id": "P11387-1", "name": "DNA topoisomerase 1", "aln": "------------------------------MSGDHLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHK---------------------------KEK--DREKSKHSN------------------------SEHKDS-EKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPK----------------------------------------------------------------------------------------------------------------------------------------KIKTEDTKKEKKRKLEEE-----EDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNI----ITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMEN-KQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTKIDA-------------------------------------------------------------------KKEQLADARRDLKSAKADAKVMKDAKTKKV-----------VESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RL46-1", "uniprot_id": "A0A8M1RL46_DANRE", "id": "A0A8M1RL46-1", "name": "DNA topoisomerase I", "aln": "------------------------------MSGDHPHKHRQVESGSVEYNSHKHKDKHKDRQHGHKEQK---------------------------RDK--ERENSKNGH------------------------SEHKSSSERKHREKEKDRLK--------------HKEKRKEEKFHGS-DGKYR-DKENGFVSPSSIKVEEDTDNHHTVKHE--KPLKRERDEDEYEHKPK----------------------------------------------------------------------------------------------------------------------------------------KVKVENEKKVKKRKQEEEDSDF-EERVEKKPKKKIKEEKK-DTTGGKKKAKNQPEEKWKWWEEERYTDGSKWRFLEHKGPVFPPPYEPLPGHIKFYYDGNAMKLSPAAEEVATFYAKMLEHEYTTNEIFRKNFFKDWRKEMTSEEKSK----ITELKKCDFTQMHEYFKAQSEARKQMSKEEKQKNKEENERILQEYGFCLMDNHRERIGNFRIEPPGLFRGRGDHPKMGKLKRRIRPEDIIINCSKDSVQPKAPPGTRWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVERIRAQYREDWRSKEMRIRQRAVALYFIDKLALRAGNEKDEGETADTVGCCSLRVEHIKLHPQLDGQDYVVEFDFLGKDSIRYYNKIPVEKRVFKNLQLFLEN-KQSEDDLFDRLNTSILNKYLQELMDGLTAKVFRTYNASITLQQQLKELTSPGENIPEKILSYNRANRAVALLCNHQRAPPKTFEKSMQNLQTKIDE-------------------------------------------------------------------KKKQLSAAKKEHKAAKADAKALHDEKSKKA-----------VETKKKAVQRISEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVSWCKKWGVPIEKIYSKTQRDKFAWAIDMADEDFEF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BH93-1", "uniprot_id": "A0A8M2BH93_DANRE", "id": "A0A8M2BH93-1", "name": "DNA topoisomerase I", "aln": "------------------------------MENELKDDPCSSEEAFSE-KPKKMKAKAKGKTKSQREGK---------------------------EKTHRKMKASEEEI------------------------METEGSGDRRSHVNVK-------------------EEPKEDPDFVTEKKGKKRKRKAD------------NTDGLLS-SAEAPLPKKKKKKVADGQENAS----------------------------------------------------------------------------------------------------------------------------------------TAKQKKMKEKKEKVKKEE-----GERPVSTKKKKTKEEIEAARALKIKKKEEEEKQRWRWWEEEKYENGIKWKFLEHKGPYFPPAYQPLPDDVKFYYNGEPVKLSLPAEEVALYFAQMLDHEYTTKEVFRNNFFKDWRKEMTLEERQL----IMDLKKCDFGELHAMHKEKVEARKNLSKEEKLVNKEANQKIVDEYGFCVLDHHRERIGNFKIEPPGLFRGRGDHPKQGMLKKRIRPEDVIINCSKESRIPEAPAGHKWKEVRHDKTVTWLASWTENVQGSCKYVMLNANSKLKGEKDWEKYEVARKLKTCVDAIRTQYQEDLKSKQMGTRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHITLHDALDDQKCVVEFDFLGKDCIRYYNKVPVTKRVFKNLKLFMEN-KQGGDDLFDRLNTASLNKHLSSLMPGLTAKVFRTYNASITLQQQLKELSNMKDNVPEKLLSYNRANRAVAVLCNHQRAPPKSFDQSMANLQAKIDS-------------------------------------------------------------------RKEQLDLAKKELKQAKKEAKGSSDNKLLVV-----------VEKKKKAVQRCEEQLLKMEVQATDREENKQIALSTSKLNYLDPRISVAWCKNMEVPLDKIYNKTLRDKFAWAVDMTELDFVF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P30189-1", "uniprot_id": "TOP1_DROME", "id": "P30189-1", "name": "DNA topoisomerase 1", "aln": "MSGDVAAENSIHIQNGGSCEVVQSNGVTTNGHGHHHHHHHSSSSSSSSKHKSSSKDKHRDREREHKSSNSSSSSKEHKSSSRDKDRHKSSSSSSKHRDKDKERDGSSNSHRSGSSSSHKDKDGSSSSKHKSSSGHHKRSSKDKERRDKDKDRGSSSSSRHKSSSSSRDKERSSSSHKSSSSSSSSKSKHSSSRHSSSSSSKDQPSYDGVFVKPEPVSQQLMHSGSVDAFQMQQLGSYEAAAAGTNFNGNGNVAGANYKNGYEESIVDIKKEEESFNNLSQASSCDYSMSQFRADEPPFVVKHEQSYAEEDSTMNYNDHDDDADEMNDDEEDVPLAMRKRKQEATDRPDGGMDNDDDDDIPLLARKKVKKEKIKKESKEKSKKRVKEEPSDDYGNVKPKKKKMKKEPEPAVSPGKRQKAKAKVEEEEVWRWWEEEKRADGVKWSTLEHKGPVFAPRYERVPRNVRFYYDGKPLELSEETEEAATFYAKMLNHDYCTKEVFNNNFFKDFRKSMTPREREI----IKDFRKCNFQEMFNYFQAESEKRKAASKEEKLIKKNENEALMKEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKDSKVPSPPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDE-DQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLELFMEH-KKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEKIKA-------------------------------------------------------------------KREAIEKCESEYHSRD--------------------------EKKGKQLERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVHMADENYRF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04786-1", "uniprot_id": "TOP1_YEAST", "id": "P04786-1", "name": "DNA topoisomerase 1", "aln": "----------------------------------------MTIADASKVNHELSSDDDDDVPLSQTLKK----------------------------------------------------------------------------------------------------------RKVASMNSASLQDEAEPYDSDEAISKISKKKTKKIKTEPVQSSSLPSPPAKKSATSKPK----------------------------------------------------------------------------------------------------------------------------------------KIKKEDGDVKVKTTKKEE---------------QENEKKKREEEEEEDKKAKEEEEEYKWWEKENEDDTIKWVTLKHNGVIFPPPYQPLPSHIKLYYDGKPVDLPPQAEEVAGFFAALLESDHAKNPVFQKNFFNDFLQVLKESGGPLNGIEIKEFSRCDFTKMFDYFQLQKEQKKQLTSQEKKQIRLEREKFEEDYKFCELDGRREQVGNFKVEPPDLFRGRGAHPKTGKLKRRVNPEDIVLNLSKDAPVPPAPEGHKWGEIRHDNTVQWLAMWRENIFNSFKYVRLAANSSLKGQSDYKKFEKARQLKSYIDAIRRDYTRNLKSKVMLERQKAVAIYLIDVFALRAGGEKSE-DEADTVGCCSLRYEHVTLKPPN-----TVIFDFLGKDSIRFYQEVEVDKQVFKNLTIFKRPPKQPGHQLFDRLDPSILNKYLQNYMPGLTAKVFRTYNASKTMQDQLDLIPN-KGSVAEKILKYNAANRTVAILCNHQRTVTKGHAQTVEKANNRIQELEWQKIRCKRAILQLDKDLLKKEPKYFEEIDDLTKEDEATIHKRIIDREIEKYQRKFVRENDKRKFEKEELLPESQLKEWLEKVDEKKQEFEKELKTGEVELKSSWNSVEKIKAQVEKLEQRIQTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKYDVPIEKIFTKTLREKFKWAIESVDENWRF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * * . ** *:*:* *.* *: :* ::: *:*. : *. :**.* ::. :*. : .: :*..***.*: : : * : :*:* :: . . :: . ::* : : : .:: :* :* ::*::.**: ***.****** *** * :*:*: ..*: :* .::: * .* * :* *:* *:.* **. * * : .. **: * . * **: *:* **:* :: ** * : :* * ** ***:*:** :***:*.**.: : ********** **: *: .* :** ***.**: :.: * * *::** * . *. .:*** * . **::*.. * ************* *:*.** :. .:. *:* ** ***.**:******: .. . ::: . : :*. :. : .. . :. :: ::: : .*::**. ::*.*:*:**:***::: :**. **::**:.** * :* **. . :: *", "identical_positions": 184, "similar_positions": 175, "identity": "17.15%" }, { "cls_id": "homologset.agr.SGD:S000005368", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5I0I9-1", "uniprot_id": "CQ10B_RAT", "id": "Q5I0I9-1", "name": "Coenzyme Q-binding protein COQ10 homolog B, mitochondrial", "aln": "MAARTSQRTLA--RVASG-CR-------PKSTTVTEARVRGSARNVRYLAPCGILMNRTLAPWASVLPKEICA--RTFFRITTP-LVNKRKEYSERRIIG----------YSMQEMYDVVSGMEDYKHFVPWCKKSDILSRR---SGYCKTRLEIGFPPVLERYTSIVTLVKP---HLVKASCTDGKLFNHLETVWRFSPGLPGYPRTCTLDFSISFEFRSLLHSQLATLFFDEVVKQMVAAFERRACKLYGPETNIPRELMLHEIHHT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3THF9-1", "uniprot_id": "CQ10B_MOUSE", "id": "Q3THF9-1", "name": "Coenzyme Q-binding protein COQ10 homolog B, mitochondrial", "aln": "MAARTSQRALA--RVASG-CH-------PKSTTVTEATARGSARDVRHLAACGVLINRTLPPCAAVLPKEICA--RTFFRISAP-LVNKRKEYSERRILG----------YSMQEMYDVVSGMEDYQHFVPWCKKSDIISRR---SGYCKTRLEVGFPPVLERYTSIVTLVKP---HLVKASCTDGKLFNHLETIWRFSPGLPGYPRTCTLDFSISFEFRSLLHSQLATLFFDEVVKQMVAAFERRACKLYGPETNIPRELMLHEIHHT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H8M1-1", "uniprot_id": "CQ10B_HUMAN", "id": "Q9H8M1-1", "name": "Coenzyme Q-binding protein COQ10 homolog B, mitochondrial", "aln": "MAARTGHTALR--RVVSG-CR-------PKSATAAGAQAP--VRNGRYLASCGILMSRTLPLHTSILPKEICA--RTFFKITAP-LINKRKEYSERRILG----------YSMQEMYDVVSGVEDYKHFVPWCKKSDVISKR---SGYCKTRLEIGFPPVLERYTSVVTLVKP---HLVKASCTDGRLFNHLETIWRFSPGLPGYPRTCTLDFSISFEFRSLLHSQLATLFFDEVVKQMVAAFERRACKLYGPETNIPRELMLHEVHHT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q567E6-1", "uniprot_id": "CQ10B_DANRE", "id": "Q567E6-1", "name": "Coenzyme Q-binding protein COQ10 homolog B, mitochondrial", "aln": "MAR--GSRCLR--RAVAE-CI-------RNLPSTAGRETPG-KSGVRYLSSCGILMTRAPPLFRAVSSRAVVAPARSFFNFAE--SSNKRKEYSERRIIG----------YSMQEMYEVVAKVEDYLLFVPWCKKSDVIFRR---SGFCKAKLTVGFPPVVENYTSLVSTVRP---HLVKASCSDGKLFNHLETVWRFSPGLPGYPRTCTLDFAISFEFRSLLHSQLATVFFDEVVKQMVSAFERRASKLYGPETQIPRELMFHEIHHT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A1W2P7J1-1", "uniprot_id": "A0A1W2P7J1_MOUSE", "id": "A0A1W2P7J1-1", "name": "Coenzyme Q-binding protein COQ10 homolog B, mitochondrial", "aln": "MASAGARRLPAPTRAAARSCCGFSLCRGARSVPTPPPGPPRPPRPMRFLISCNLFLPRAAQALAAEAGLPHSR---SFMGFAAP-FTNKRKAYSERRIMG----------YSMQEMFEVVSNVQEYREFVPWCKKSLVVSSR---KGHLKAQLEVGFPPVLERYTSAVSMVKP---HMVKAVCTDGKLFNHLETIWRFSPGIPSYPRTCTVDFSISFEFRSLLHSQLATMFFDEVVKQNVAAFERRAATKFGPETAIPRELMFHEVHQT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JYY6-1", "uniprot_id": "A0A0G2JYY6_RAT", "id": "A0A0G2JYY6-1", "name": "Coenzyme Q-binding protein COQ10 homolog B, mitochondrial", "aln": "MASAGARRLPVPTRAAARSCCGFSLCRGARSLPTPPPGSPRSPRPMRFLISCNLLLPRAAQVLAAEVGLPPSR---SFMGFAAP-FTNKRKAYSERRIMGSLAFNSSCSRYSMQEMFEVVSNVQEYREFVPWCKKSLVVSSR---KGHLKAQLEVGFPPVLERYTSAVSMVKP---HMVKAVCTDGKLFNHLETIWRFSPGIPAYPRTCTVDFSISFEFRSLLHSQLATMFFDEVVKQNVAAFERRAATKFGPETAIPRELMFHEVHQT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96MF6-1", "uniprot_id": "CQ10A_HUMAN", "id": "Q96MF6-1", "name": "Coenzyme Q-binding protein COQ10 homolog A, mitochondrial", "aln": "MAWAGSRRVPAGTRAAAERCCRLSLSPGAQ--PAPPPGPLPPPRPMRFLTSCSLLLPRAAQILAAEAGLPSSR---SFMGFAAP-FTNKRKAYSERRIMG----------YSMQEMYEVVSNVQEYREFVPWCKKSLVVSSR---KGHLKAQLEVGFPPVMERYTSAVSMVKP---HMVKAVCTDGKLFNHLETIWRFSPGIPAYPRTCTVDFSISFEFRSLLHSQLATMFFDEVVKQNVAAFERRAATKFGPETAIPRELMFHEVHQT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PBN4-1", "uniprot_id": "CQ10X_DANRE", "id": "Q6PBN4-1", "name": "Coenzyme Q-binding protein COQ10 homolog, mitochondrial", "aln": "MAEKATSLFLRAMEISEK--------------QSFDVMRRNSSCTIRHLSSCGILETRRVSLPPPPSASSQMVPSRSFINLTAP-LIMRRMEYSESRSIN----------YSPEQMYDVVANVEQYQQFVPWCKKSKVTRGR---NGDMRAQLEIGFPPIVERYTSEVTVIPN---HQVRAVCTDGSLFNHLETLWRFTPGAAG--QSCNVEFFVTFEFKSLLHSQLATMFFDEVVKQMVNAFETRAKKLYGTGVHRQQASLRRAI---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MLL3-1", "uniprot_id": "COQ10_DROME", "id": "Q8MLL3-1", "name": "Coenzyme Q-binding protein COQ10, mitochondrial", "aln": "MLKGSTLKALDVRILWPLIETRSAG---KCKLHNPRPTPNRNIAAAKLIVTLRLLLSCCSGGHQRSFSSSTHR---SYITFND--FRKKHRWYTKKELVG----------YSMQDMYSVVSDVSNYHKFVPYVKRSDVHSRG---SEGFKADLIVGFPPLNEAYTSQVTLVPP---SLVKSECHDGRLFNYLLNEWSFKPGLKDIPNSCVLDFKVSFEFKSLLHSNVANIFFDLICDQMENAFIQEVRRRSGPPSIRSHVLTSDRS---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08058-1", "uniprot_id": "COQ10_YEAST", "id": "Q08058-1", "name": "Coenzyme Q-binding protein COQ10, mitochondrial", "aln": "--------------------------------------------MVLIIRPSQTLILFRKAMLKPIGRYPLKR---NFFGLSGTNHTIREQRYVLRKAIN----------APPSTVYAAVSEVAQYKEFIPYCVDSFVDKRNPVDNKPLIAGLRVGFKQYDEEFICNVTCKDTDHTYTVVAETISHNLFHLLISKWTIMP-HPNRPNAAMVELLLRFKFKSRIYNSVSLIFAKTVTELVMNAFAKRAYHLVRLAMLKPSSKEGSP----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : .:: : :. * . :. . . :: .*: : :* *:*: * : . : * :** * : . *: * : . **: * . * : * .:. ::: : *:*:* ::..:: :* . : . ** .. ", "identical_positions": 23, "similar_positions": 55, "identity": "8.55%" }, { "cls_id": "homologset.agr.SGD:S000005370", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7Z1-1", "uniprot_id": "G3V7Z1_RAT", "id": "G3V7Z1-1", "name": "RNA 3'-terminal phosphate cyclase-like protein", "aln": "---MATQAHSLSYAGCNFLRQRLVLSTLSGRPVKIRRIRARDD-NPGLRDFEASFIRLLDKITNGSRIEINQTGTTLYYQPGLLYGGSVEHDCSVLRGIGYYLEALLCLAPFMKHPLKIVLRGVTNDQVDPSVDVLKATALPLLKQFGIDGESFELKILRRGMPPGGGGEVLFSCP-VRKVLKPVQLTDPGKIKRIRGMAYSVRVSPQMANRIVDSARGILNKFIPDIYIYTDHMKGVNSGKSPGFGLSLVAETTNG--TFLSAELASNP--QGQGAAVLPEDLGRNCAKLLLEEIYRGGCVDSTSQSLVLLLMTLGQQDVSKVLLG--PLSPYTIEFLRHLKSFFQVMFKVETKPCG-----EELKGGDKVLMTCVGIGFSNLSKTLK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJT0-1", "uniprot_id": "RCL1_MOUSE", "id": "Q9JJT0-1", "name": "RNA 3'-terminal phosphate cyclase-like protein", "aln": "---MATQAHSLSYAGCNFLRQRLVLSTLSGRPVKIRRIRARDD-NPGLRDFEASFIRLLDKITNGSRIEINQTGTTLYYQPGLLYGGSVEHDCSVLRGIGYYLEALLCLAPFMKHPLKIVLRGVTNDQVDPSVDVLKATALPLLKQFGIDGESFELKILRRGMPPGGGGEVLFSCP-VRKVLKPVQLTDPGKIKRIRGMAYSVRVSPQMANRIVDSARSILNKFIPDIYIYTDHMKGVSSGKSPGFGLSLVAETTNG--TFLSAELASNP--QGQGAAVLPEDLGRNCAKLLLEEIYRGGCVDSTNQSLVLLLMTLGQQDVSKVLLG--PLSPYTIEFLRHLKSFFQVMFKVETKPCG-----EELKGGDKVLMTCVGIGFSNLSKTLK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2P8-1", "uniprot_id": "RCL1_HUMAN", "id": "Q9Y2P8-1", "name": "RNA 3'-terminal phosphate cyclase-like protein", "aln": "---MATQAHSLSYAGCNFLRQRLVLSTLSGRPVKIRKIRARDD-NPGLRDFEASFIRLLDKITNGSRIEINQTGTTLYYQPGLLYGGSVEHDCSVLRGIGYYLESLLCLAPFMKHPLKIVLRGVTNDQVDPSVDVLKATALPLLKQFGIDGESFELKIVRRGMPPGGGGEVVFSCP-VRKVLKPIQLTDPGKIKRIRGMAYSVRVSPQMANRIVDSARSILNKFIPDIYIYTDHMKGVNSGKSPGFGLSLVAETTSG--TFLSAELASNP--QGQGAAVLPEDLGRNCARLLLEEIYRGGCVDSTNQSLALLLMTLGQQDVSKVLLG--PLSPYTIEFLRHLKSFFQIMFKIETKPCG-----EELKGGDKVLMTCVGIGFSNLSKTLK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56175-1", "uniprot_id": "RCL1_DROME", "id": "P56175-1", "name": "Probable RNA 3'-terminal phosphate cyclase-like protein", "aln": "MPPIAQEGNCLIYRGSNFLKQRLILACLSGKPVKISQIRSEDETAPGLREYEISLIRLLDKITNGTKIELNPAGTSVMFSPGLLHGGQLNHDCCVQRGIGYYLDALIALGPFCKSPLQCTLRGVTNSKDSPSVDHIKGAALSLLKRFLLVDEGLELKVVRRGVAPLGGGEIIFRCP-VRKSLRAIQFQSQGMVKRIRGTVYACKVSPAMANRTVEAAKGCMLKFLPDVYIYTDQNKGKMSGNSPGFGICLIAETTDG--VCFAADCCSNTREESEDTPSIPENLGKEVALRLLDEIYRGGCVDSSYQWLAALYIALGQKHVSKFLTG--ALSNYTVHFLQHLRDFFSITFKLENPEAEDEDEAENVRGAQKVLMACVGIGYTNINKRVI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08096-1", "uniprot_id": "RCL1_YEAST", "id": "Q08096-1", "name": "rRNA processing protein RCL1", "aln": "--MSSSAPKYTTFQGSQNFRLRIVLATLSGKPIKIEKIRSGDL-NPGLKDYEVSFLRLIESVTNGSVIEISYTGTTVIYRPGIIVGGASTHICPSSKPVGYFVEPMLYLAPFSKKKFSILFKGITASHNDAGIEAIKWGLMPVMEKFGVR--ECALHTLKRGSPPLGGGEVHLVVDSLIAQPITMHEIDRPIISSITGVAYSTRVSPSLVNRMIDGAKKVLKNLQCEVNITADVWRGENSGKSPGWGITLVAQSKQKGWSYFAEDIGDAG--------SIPEELGEKVACQLLEEISKSAAVGRNQLPLAIVYMVIGKEDIGRLRINKEQIDERFIILLRDIKKIFNTEVFLKP---------VDEADNEDMIATIKGIGFTNTSKKIA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : *.: :: *::*: ***:*:** :**: * ***:::* *::**::.:***: **:. :**:: : **:: ** * * : :**:::.:: *.** * :. ::*:* .: ...:: :* :.::::* : *: ::** .* ****: : : .:: . :. * * .*: :*** :.** ::.*: : :: :: * :* :* **:***:*: *:*::.. :: : . :**:**.: * **:** :...*. . *. : :.:*::.:.:. . :. : :*:.::.:*. . :: : . :.:: : ***::* .* : ", "identical_positions": 89, "similar_positions": 151, "identity": "22.88%" }, { "cls_id": "homologset.agr.SGD:S000005371", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q50L42-1", "uniprot_id": "PA24E_MOUSE", "id": "Q50L42-1", "name": "Cytosolic phospholipase A2 epsilon", "aln": "MQSIPHSDEADVAGMTHASEGHHGLGTSMLVPKNPQGEEDSKLGRNCSGFEDAQDPQTAVPSSPLLSMASCSSQEGSSPCHLLTVRIIGMKNVRQ---ADILSQTDCFVTLWLPTASQK-KLKTRTISNCLHPEWDESFTFQIQTQVKNVLELSVCDEDTLTQNDHLLTVLYDLSKLCLRNKTHVKFPLNP---EGMEELEVEFLLEENFSSSETLITNGVLVSRQVSCLEVHAESRRPR---KRKKNKDLLVMVTDSFENTQ--------RVPPCQEPCYPNSACFHYPKYSQPQLYAEAPKSHCNFRL-----CCCGTHRNDPVCQPLNCLSDGQVTTLPVGEN----YELHMKSSPCSD-TLDVRLGFSLCQEEVEFVQKRKMVVAKTLSQMLQLEEGL---HEDEVPIIAIMATGGGTRSMVSLYGHLLGLQKLNFLDASTYITGLSGATWTMATLYSDPEWSSKNLETVVFEARRHVVKDKMPALFPDQLYKWREDLQKHSQEGYKTTFTDFWGKLIEYSLGDKKNECKLSDQRAALCRGQNPLPIYLTIN--VKDD-VSNQDFREWFEFSPYEVGMQKYGAFIPSELFGSEFFMGRLMKRIPEPEMCYMLGLWSSIFSLNLLDAWNLSHTSEEF-----------------------FYRWTRERLHDIEDDPILPEIPRCDDNPLETTVVIPTTWLSNTFREILTRRPFV--------------SEFHNFLYGMQLHT--------DYLQNR--QFSMWKDT-------VLDTFPNQLTQFAKHLNLLDTAFFVNSSYAPLLRPERKVDLIIHLNYCAG-----SQTKPLKQTCEYCTEQKIPFPSFS-ILEDDNSLKECYVMENPQ---EPDAPIVAYFPLISDTFQKYKAPGVER-SPDELELG--QLNIYGPKSPYATKELTYTEAAFDKLVKLSEYN-----ILNNRDKLIQALRLAMEKKRMRSQCPS-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ANS2-1", "uniprot_id": "A0A8I6ANS2_RAT", "id": "A0A8I6ANS2-1", "name": "Phospholipase A2", "aln": "----------------------------MLQRQMPAWVSHS-LSDTCQ----AED-------------GRCS-EEGSSPCHLLTVRIISMKNVRQ---ADILSQTDCFVTLWLPTASQK-KLRTRTISNCPHPEWNESFTFQIQTRVKNVLEFSICDEDTLTQSDHLLTVLYDLSKLCLRNKTHVKFPLNP---EGMEELEVEFLLEENVSSSETLITNGVLVSRQVSCLEVHAESRRPR---KRKKNKNLLVMVTDSFENTQ--------CVQPCLEPCCPNPACFHYPKYSQPQLYAEAPKSHWSYRL-----CCCEAQRNDTVCQPLDCLSDGQPMTLPLGEN----YELHMKSSPCSN-TLDVRLGFSLCQEEVEFLQKRKVAVTKALNQVLQLEEGL---HEHEVPMIAIMATGGGTRSMVSLYGHLLGLQKLNLLDCSVYLTGLSGATWTMATLYSDPEWSSKDLEPVVFEARRHVVKDKMPALYPDQLCKWQEELRQHSQEGYKTTFTDFWGKLVEYSLGDKKNECKLSEQRAALCRGQNPLPIYLTIN--VKDD-VSNQDFREWFEFSPYEVGMQKYGAFIPTELFGSEFFMGRLMKRIPEPEMCYMLGLWSSIFSLNLLDAWNLSHTSEEF-----------------------FYRWTREKLHDIEDDPLLPEIPRCDANPLETTVVIPATWLSNTFREILTHRPLV--------------SEFHNFLYGLQLHT--------DYLQNK--QFCMWKDT-------VLDTFPNQLTQFTKHLNLLDTAFFVNSSYAPLLRPERKVDLIIHLNYCAG-----SQTKPLKQTCEYCTEQNIPFPNYS-IQEDDKSLKECYVMENPQ---EPDAPIVVYFPLINDTFQKYKAPGVER-SPEELELG--QLNIYGPKSPYATKELTYTEAAFDKLVKLSEYN-----ILNNKDKLIQAVRLAMEKKRMKSQCPS-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C871-1", "uniprot_id": "PA24B_MOUSE", "id": "P0C871-1", "name": "Cytosolic phospholipase A2 beta", "aln": "------------------------------------------------------------------------MQAKVPETCLLTVRVLRASGLPS---KDLVTSSDCYVTLNLPTASSH-TLQTRTVKNSRNPVWNQNFHFRIHRQLKNVMELKVFDHDLVTRDDPVLSVLFDVGTLQIGTQR-QSFSLGT---QEKGCLEVEFRLQTLTDCEEQLISNGIVVARELSCLHVELKRTGD----PKRSERKVQLVVAGACEGPQ--------DAS----AGTG-SFHFHYPACWEQELNVHLQ-----------------DDPHEQLKVPLRTLPSSQLVRLVFPTSQEPLMRLELKKEEGPK-ELAVRLGCGPCPEEQAFLSKRKQVVAAALKKALQLDQDL---HEDEIPVIAVMATGGGIRAMTSLYGQLAGLQELGLLDCISYITGASGSTWALANLYEDPEWSQKDLAGPTEVLKTQVTKSKLGALAPSQLWRYRQELAERARLGHPTCFTNLWALINEALLHDKPHEHKLSDQREALSRGQNPLPIYCALN--SKEQGLSTFDFGEWCEFSPYEVGFPKYGAFISSELFGSEFFMGRLVKQLPESRICFLEGIWSNLFAASLQDSLYWSSEPSQ------------------------FWDRWAQDQANLDKEQVP-------HLKIAEPPTMAG-RIAELFTDLLTKRPLA--------------HATHNFTRGLHFHK--------DYFQNS--HFSAWKAS-------KLDRLPNQLTPTEPHLCLLDVGYLINTSCPPLLQPTRDVDLILSLDYNLY-----GAFQQLQLLSRFCQEQGIPFPSISPSPEEQRQPQECHLFCDPA---QPEAPAVLHFPLVNDSFQDYSAPGVPR-TSEEKAAG--EVNLSSSDSPYHYTKVTYSQEDVDKLLRLTHYN-----ICNNQDRLREAMHQAVQRRR-KRKQFRPE-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A1I6-1", "uniprot_id": "D4A1I6_RAT", "id": "D4A1I6-1", "name": "Phospholipase A2", "aln": "-----------------------------------------MALQTCP----------------------VYMQAKVPETHLLTVRVLQASGLPS---KDLVTSSDCYVTLNLPTASSG-TLQTRTVKNSRNPVWNQNFHFRIHRQLKNVMELKVFDQDLMTKDDPVLSVLFDVGTLQVGTQR-QSFSLSA---QEDGRLEVEFRLQTLTDCEEQLISNGILVAQELSCLHVELKRTGD----PKRSERKVQLVVAAACEGPQ--------EAP----VGTG-SFRFHYPACWEQELSVHLQ-----------------DDPHEQLKVPLRTLPSSQLVRLVFPTSQEPLMRLELKKEDGPK-ELAVRLGCGPCPEEQAFLSKRKQVVAAALKKALQLDQDL---QEDEIPVIAVMATGGGIRAMTSLYGQLAGLKELGLLDCISYITGASGSTWALANLYEDPEWSQKDLAGPTEMLKTQVTKSKLGALAPSQLWRYRQELAERARLGYPTCFTNLWALINEALLHDKPHEHKLSDQREALSRGQNPLPIYCALN--SKEKGLSTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEFFMGRLVKQLPESRICFLEGIWSNLFAASLQDSFYWSSEPSQ------------------------FWDRWAQDQANLDKEQVS-------HLKIAEPPTAAG-KIAELFTDLLTKRPLA--------------QATHNFMRGLHFHK--------DYFHHP--HFSTWKAS-------KLDKFPNQLTPAEPHLCLLDVGYFINTSCPPLLQPTRDVDLILSLDYNLS-----GAFQQLQLVSRFCQEQGIPFPSISPSPEEQRQPQECHMFCDPA---QPEAPAVLHFPLVNDSFRDHSAPGVPR-TSEEKTAG--EVNLSSSNSPYDYTKVTYSQEDVDKLLRLTHYN-----ICNNQDRLREAMHQAVQRRR-NRRQFRRE-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C869-1", "uniprot_id": "PA24B_HUMAN", "id": "P0C869-1", "name": "Cytosolic phospholipase A2 beta", "aln": "-----------------------------------------------------------------------MAVAEVSRTCLLTVRVLQAHRLPS---KDLVTPSDCYVTLWLPTACSH-RLQTRTVKNSSSPVWNQSFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSP---QGEGRLEVEFRLQSLADRGEWLVSNGVLVARELSCLHVQLEETGD----QKSSEHRVQLVVPGSCEGPQ--------EAS----VGTG-TFRFHCPACWEQELSIRLQ-----------------DAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMRVELKKEAGLR-ELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDL---QEDEIPVVAIMATGGGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTELLKTQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHDHKLSDQREALSHGQNPLPIYCALN--TKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEFFMGQLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQ------------------------FWDRWVRNQANLDKEQVP-------LLKIEEPPSTAG-RIAEFFTDLLTWRPLA--------------QATHNFLRGLHFHK--------DYFQHP--HFSTWKAT-------TLDGLPNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSLDYNLH-----GAFQQLQLLGRFCQEQGIPFPPISPSPEEQLQPRECHTFSDPT---CPGAPAVLHFPLVSDSFREYSAPGVRR-TPEEAAAG--EVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYN-----VCNNQEQLLEALRQAVQRRR-QRRPH--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q50L43-1", "uniprot_id": "PA24D_MOUSE", "id": "Q50L43-1", "name": "Cytosolic phospholipase A2 delta", "aln": "----------------------------MWSGDRRVGMESLSPERLHG----------------------HPYQEEASVFCRLTVKILEARSLPR---ADLLSQADPYVTVQLPTASGM-KFKTQTVTNSSHPVWNETFSFLIQSQVKNILELTIYDEDVITKDDICFKVSYDVSEILPGQLLQKTFSLNP---QGPEELDVELLMERTWDPPENLITNNVLVARELSHLDVSLDRAGNTAMAAGQDKLELELMLKGSYEDTQ--------TFF----PDTAFTFSFHYMRGQDTELNGYLRGPRNSG--------WNSDTSVTPFNVPLMSLAAGKEMTIDIPAMKAPEGKLQLKTDCCPK-ELSVRLSYGLCPEEQAFLSRRKKVVAAALKQALQLDEDL---NEDEVPVVGINAEGGGMRAMISLYGHLLALQKLGLLDCVTYFSGISGSTWTMAHLYRDPEWSQRDLEGPISHAREHVAKTLLKEFLPEHLASYRQTLKLREEQGYTVTVADLWGLVLESKLHGQVTDQKLSGQRAALERGQNPLPLYLSLN--VKENHLETLHFKEWVEFSPYEVGFLKYGGFVPSELFGSEFFMGRLMKRLPESQICFLEGIWSNLFSVNLMDIWYDITYGKD-------------------------SNNFPVDVRNSEKEFSGSAGT---SSGVEAPWLESGTALAQALKGFLTGRPFH--------------QRSANFLHGLQLHR--------DYCNQR--HFSTWADC-------NLDDTPNQLTPQDPQLCLIDAGCFMNSSCPSLFRPGRQVDLIISFNYNQS-----LPFKGLQQSEKYSRARGLPFPRVEPSPEDHSQPQECYLFSDPT---CPEAPVVLHFPLVNDSFRDHSAPGVRR-SPDELKAG--QVNLTGAASPYFMYNMTYKNEDFDRLLQLSDYN-----VQNNQGTILQALRTVLKRRASETRPLGVKT----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZQH6-1", "uniprot_id": "D3ZQH6_RAT", "id": "D3ZQH6-1", "name": "Phospholipase A2", "aln": "----------------------------MWSGDRRVVMESLSPERLPV----------------------YPRQEEASVFCQLTVKILEARSLPR---ADLLSKADPYVTLRLPTASGR-KFKTQTVTNSSNPVWNETFSFLIQSQVKNILELTVYDEDLITKDDICFKISYDISEILPGQLVQKTFSLNP---QGPEELDVEFLVERTCDPPENLITNNVLVARELSHLDVSLDRAGSTTMAAGQDKLELELMLKGSYEDTQ--------TFL----PDTAFTLSFHYMRSQDTELNGYLRSSRNSD--------WNSDTSATPFNVPLTLLAAGKEVTVDIPATKDPERKLQLKTDSCPK-ELSVRLSYGLCPEEQAFLGRRKKLVAAALKQALQLDEDL---KEDEVPVVGINAEGGGMRAMISLYGHLLALQKLGLLDCVTYFSGISGATWTMAHLYRDPEWSQKDLEGPISHAREHVAKSLLKEFLPEHLASYRQTLKLREEQGYTVTIADLWGLVLESKLHGQVTDQKLSEQRAALERGQNPLPLYLSLN--VKENHLETLHFKEWVEFSPYEVGFLKYGGFVPSELFGSEFFMGRLMKRLPESQICFLEGIWSNLFSVNLMDIWYDITSGRD-------------------------SNDFPVDVQNSEKEPSSSAGV---SSGVEAPWLQPGTALAQAFKGFLTGRPFN--------------QRSANFLHGLQLHR--------DYCNQR--DFSTWADC-------NLDDTPNQLTPQDPQLCLIDAGCFMNSSCPSLFRSGRQVDLILSFNYNQS-----FPFKGLQQSGKYCSAQGLPFPRVEPSPEDHLQPQECYLFSDPT---CPEAPAVLHFPLVNDSFQDHSAPGVRR-SPDELKAG--QVDLTGVASPYFLYNMTYKNEDFDRLLRLSEYN-----IQNNQGTILQALKTVLKRRASETRPLGVKT----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86XP0-1", "uniprot_id": "PA24D_HUMAN", "id": "Q86XP0-1", "name": "Cytosolic phospholipase A2 delta", "aln": "-------------------------------------MESLSPGGPPG----------------------HPYQGEASTCWQLTVRVLEARNLRW---ADLLSEADPYVILQLSTAPGM-KFKTKTLTDTSHPVWNEAFRFLIQSQVKNVLELSIYDEDSVTEDDICFKVLYDISEVLPGKLLRKTFSQSP---QGEEELDVEFLMEETSDRPENLITNKVIVARELSCLDVHLDSTGSTAVVADQDKLELELVLKGSYEDTQ--------TSF----LGTASAFRFHYMAALETELSGRLRSSRSNG--------WNGDNSAGYLTVPLRPLTIGKEVTMDVPAPNAPGVRLQLKAEGCPE-ELAVHLGFNLCAEEQAFLSRRKQVVAKALKQALQLDRDL---QEDEVPVVGIMATGGGARAMTSLYGHLLALQKLGLLDCVTYFSGISGSTWTMAHLYGDPEWSQRDLEGPIRYAREHLAKSKLEVFSPERLASYRRELELRAEQGHPTTFVDLWALVLESMLHGQVMDQKLSGQRAALERGQNPLPLYLSLN--VKENNLETLDFKEWVEFSPYEVGFLKYGAFVPPELFGSEFFMGRLMRRIPEPRICFLEAIWSNIFSLNLLDAWYDLTSSGES-----------------------WKQHIKDKTRSLEKEPLTTSGT---SSRLEASWLQPGTALAQAFKGFLTGRPLH--------------QRSPNFLQGLQLHQ--------DYCSHK--DFSTWADY-------QLDSMPSQLTPKEPRLCLVDAAYFINTSSPSMFRPGRRLDLILSFDYSLS-----APFEALQQTELYCRARGLPFPRVEPSPQDQHQPRECHLFSDPA---CPEAPILLHFPLVNASFKDHSAPGVQR-SPAELQGG--QVDLTGATCPYTLSNMTYKEEDFERLLRLSDYN-----VQTSQGAILQALRTALKHRTLEARPPRAQT----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q50L41-1", "uniprot_id": "PA24F_MOUSE", "id": "Q50L41-1", "name": "Cytosolic phospholipase A2 zeta", "aln": "--------------------MPWTLQPKWLAGKGLPLLGAILLRKTEKS-----------------EPQWKHRRQETHPYYDLQVKVLRARNIQH---TDKLSKADCYVRLWLPTASVS-PSQTRTVVNSSDPEWNETFPYQIHGAVKNVLELALYDEDVLD-SDNVFSILFDTSTLQLGQPCTKNFTRQQ----DPKELEVEFTLEKSQTPASEVVTNGVLVAHPCLRIQGTVTGDKTAS-LGELGSRQIQLAVPGAYEKPQ--P-----LQPTS-EPGLPVNFTFHVNPVLSPKLHIKLQEQLQVFHSGPSDELEAQTSKMDKASILLSSLPLNEELTKLVDLEEGQQVSLRMKADMSSSGDLDLRLGFDLCDGEQEFLDKRKQVASKALQRVMGLSEAL---HCDQVPVVAVLGSGGGTRAMTSLYGSLAGLQELGLLDAVTYLSGVSGSSWCISTLYRDPSWSQKALQGPIKYASERVCSSKIGMLSPKQFEYYSREKRAWESRGHSMSFTDLWGLIIEYFLNQEENPAKLSDQQETVSQGQNPYPIYASIN--VHKN-ISGDDFAEWCEFTPYEVGFPKYGAYVPTELFGSEFFMGRLLHFWPEPRICYLQGMWGSAFAASLYEIFLKLGGLSLS-----------------------FLDWHRGSVSVTDDWPKLRKQD---PTRLPTRLFTPMSSFSQAVLDIFTSRITC--------------AQTFNFTRGLCMYK--------DYTARK--DFVVSEDAWHSHNYGYPDACPNQLTPMKDFLSLVDGGFAINSPFPLVLQPQRAVDLIVSFDYSLE-----GPFEVLQVTEKYCRDRGIPFPRIEVDPKDSEDPRECYLFAEAE---DPCSPIVLHFPLVNRTFRTHLAPGVERQTAEEKAFG--DFIINGPDTAYGMMDFTYEPKEFDRLVTLSRYN-----VLNNKETIRHALQLALDRRRQAGGRVGG------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z9B7-1", "uniprot_id": "D3Z9B7_RAT", "id": "D3Z9B7-1", "name": "Phospholipase A2", "aln": "--------------------MPWTLQPKWLASKGLPLLGAILLRETEKR-----------------ETQWKHWRQETHPYYDLQVKVLRARNIQH---TDKLSKADCYVQLWLPTASFS-PTQTRTVVNCSDPEWNETFHYRIHSAVKNVLELALYDKDVLD-SDKIFSVLFDLSTLQLGQPYTKTFTQKQPGLTDPKELQVEFTLEKSQMPACEVITNGVLVAHPCLRIQGTVTGDKTAS-LGEFGSREIQLAVPGAYEKPQSVP-----LQPTTVEPGLPATFIFHMNPVLSPRLNIALQEKLLVSHSGPSDELESQTSKMEEASILLSSLPLNQESTRLMNLEEGQQVTLRMKADMRSE-DLDLRLGFELCSGELEFLDKRKQVVSKALQQVMRLSEAP---HCDQVPVIAVLGSGGGTRAMTSLYGSLAGLQELGLLDAVTYLSGVSGSSWCISTLYKDPSWSQKTLQGPIRHASARVCSSKVGMLSPERFEYYTREKKTWESRGHSMSFTDLWGLIIEYFLNQEENPAKLSDQQEMVSQGQNPYPIYASIN--VHNN-ISGEDFAEWCEFTPYEVGFPKYGAYVPTELFGSEFFMGRLLQHWPEPRICYLQGMWGSAFAASLYEIFLKMRGPRLG-----------------------FLDWHRGTVSVTDDWPKLRKQD---PTRLPTRLFTSKSFFSKAVLDIFTSRFTC--------------AQTFNFTRGLCLYK--------DYTARK--DFVVSEDAWHSDNYKHLDACPNQLTPMKDFLSLVDGGFAINSPFPLILQPQRAVDLIVSFDYSLE-----APFEVLQVTEKYCRDRGIPFPRIEIDPKDSKDPRECYLFTEAE---DPCSPIVLHFPLVNRTFRKHLAPGVERQTAEEKAFG--DFIINGPDTAYGMMDFTYEPIEFDRLVTLSRYN-----VLNNIETIRRALQLALDRR-QAGGRAGA------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9Q6G1-1", "uniprot_id": "A0A8M9Q6G1_DANRE", "id": "A0A8M9Q6G1-1", "name": "Phospholipase A2", "aln": "---------------MFFSSFLESSVPTGLSCRNFRHMHDIMNKTTYVSCTVLRLHCR-------PAEEKTMLKIELMPYWNLSVTVLRGTFSQS---YDVLSKNDCYVTLKLPTASAC-CHRTKTVKNSNEPKWNETFHFRVHSGIKNILEFHMFDADKLTKDDHLSTILFDISNLTPGQKQTKCFMSDD---ERRGALWVEFEMTVSSEKPIPYFSNGVLMAGPFCALDVKLQKHLKTN-----AENKMMLRLRGAYKEDCMILSSDEN-------SSCLQNTCFYINRDLETEFSLLPPKAGAEMDEK------YANTADILSSVPMKPLSAKQQMKLSMPIAQG-EVHLELNTEDCLDEEMDVRLEFDIPVEEKNFLLKRRKVVSQALQKALNLGSAP---DPSKVPLVAVVCSGGGTRAMTATFGGLRALQTLQLLDAVSYITGVSGSTWTMASLYSDANWSNSDLNVAMESVKKEISKSVFSVFSPEQLQHYKEKMEEREKQGHLVSLIDMWGLAIEYLIHGKKKLGTLSDQQMALCNGQNPLPIYTALN--MKNGKTGCIIETEWCEFTPYEVGFTKYGAFIPAQNYGSEYYLGHMVKKLPEAGIYSLLGIWSSVFSLSLTQLWTVVTGVIPS-----------------------WASKVGEEVNHTDTDNKPSTSN--------TLHVNPMTELAKKLSNFLTSRPII--------------SQVFNFLRGFQLHR--------NYTENC--DFTAWKDT-------HPDAFPNSLTPADATLGLVDSAFVLKSGFPPVLRSNRLADVILSLNYAWDS----DHFKILKETQEYCREHKTLFPKIDFKKLETEPIREVYVFEDEE---NPEVPIVLHFPLINVSFKQFKAPGKRREGKVEMKEGDFDVDFTRMFCPFSTLNLTYEPENFQKLSSLTAYN-----ILNNKDVILNALKKALKRNKEKNPITTNVSKF--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P47713-1", "uniprot_id": "PA24A_MOUSE", "id": "P47713-1", "name": "Cytosolic phospholipase A2", "aln": "-----------------------------MSFIDPYQ----------------------------------HIIVEHQYSHKFTVVVLRATKVTKGTFGDMLDTPDPYVELFISTTPDS-RKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMD-ANYVMDETLGTATFPVSSMKVGEKKEVPFIFNQ-----VTEMILEMSLEVCSCP---------------------------------------------------------------------------------------------------------------------------------------------------------DLRFSMALCDQEKTFRQQRKENIKENMKKLLGPKKSEGLYSTRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYIAGLSGSTWYMSTLYSHPDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIQNRMSMTLSSLKEKVNAARCPLPLFTCLH--VKPD-VSELMFADWVEFSPYEIGMAKYGTFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQNKGSTMEEELE------------NITAKHIVSNDSSDSDDEAQGPKGTENEEAEKEYQSDNQASWVHRMLMALVSDSALFNTR-------EGRAGKVHNFMLGLNLNTSYPLSPLRDFSSQD--SFDD-ELDAAVADPDEFERIYEPLDVKSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDTSPPFKELLLAEKWAKMNKLPFPKIDPYVFDREGLKECYVFKPKNPDVEKDCPTIIHFVLANINFRKYKAPGVLRETKEEKEIAD-FDIFDDPESPFSTFNFQYPNQAFKRLHDLMYFN-----TLNNIDVIKDAIVESIEYRRQNPSRCSVSLSNVEARKFFNKEFLSKPTV---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50393-1", "uniprot_id": "PA24A_RAT", "id": "P50393-1", "name": "Cytosolic phospholipase A2", "aln": "-----------------------------MSFIDPYQ----------------------------------HIIVEHQYSHKFTVVVLRATKVTKGTFGDMLDTPDPYVELFISTTPDS-RKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMD-ANYVMDETLGTATFPVSSMKVGEKKEVPFIFNQ-----VTEMILEMSLEVCSCP---------------------------------------------------------------------------------------------------------------------------------------------------------DLRFSMALCDQEKTFRRQRKENIKENMKKLLGPKKSEGLYSTRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYVAGLSGSTWYMSTLYSHPDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIQNRMSTTLSSLKEKVSAARCPLPLFTCLH--VKPD-VSELMFADWVEFSPYEIGMAKYGTFMTPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQNKGSTMEEELE------------NITAKHIVSNDSSDSDDEAQGPKGTENEDAEREYQNDNQASWVHRMLMALVSDSALFNTR-------EGRAGKEHNFMLGLNLNTSYPLSPLRDFSPQD--SFDDDELDAAVADPDEFERIYEPLDVKSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDTSPPFKELLLAEKWAKMNKLPFPKIDPYVFDREGLKECYVFKPKNPDVEKDCPTIIHFVLANINFRKYKAPGVLRETKEEKEIAD-FDIFDDPESPFSTFNFQYPNQAFKRLHDLMYFN-----TLNNIDVIKDAIVESIEYRRQNPSRCSVSLSNVEARKFFNKEFLSKPTAESI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47712-1", "uniprot_id": "PA24A_HUMAN", "id": "P47712-1", "name": "Cytosolic phospholipase A2", "aln": "-----------------------------MSFIDPYQ----------------------------------HIIVEHQYSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFISTTPDS-RKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMD-ANYVMDETLGTATFTVSSMKVGEKKEVPFIFNQ-----VTEMVLEMSLEVCSCP---------------------------------------------------------------------------------------------------------------------------------------------------------DLRFSMALCDQEKTFRQQRKEHIRESMKKLLGPKNSEGLHSARDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYVAGLSGSTWYMSTLYSHPDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIHNRMNTTLSSLKEKVNTAQCPLPLFTCLH--VKPD-VSELMFADWVEFSPYEIGMAKYGTFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQSRGSTMEEELE------------NITTKHIVSNDSSDSDDESHEPKGTENEDAGSDYQSDNQASWIHRMIMALVSDSALFNTR-------EGRAGKVHNFMLGLNLNTSYPLSPLSDFATQD--SFDDDELDAAVADPDEFERIYEPLDVKSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMNKLPFPKIDPYVFDREGLKECYVFKPKNPDMEKDCPTIIHFVLANINFRKYRAPGVPRETEEEKEIAD-FDIFDDPESPFSTFNFQYPNQAFKRLHDLMHFN-----TLNNIDVIKEAMVESIEYRRQNPSRCSVSLSNVEARRFFNKEFLSKPKA---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64GA5-1", "uniprot_id": "PA24C_MOUSE", "id": "Q64GA5-1", "name": "Cytosolic phospholipase A2 gamma", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELSSGVCPATRLQEAEKAAVHKRSPKVLEALRKLN--------IQADQAPVIAVLGSGGGLRAHIACLGVLSELKELGLLDAVTYLAGVSGSTWALSSLYTK----NGNMEGIEEELKHRYEKNEWDFHES-------LEKAIQASKRENYSLTDFWAYLIVSRQIRELQDSNLSSLKKQVEEGVLPYPIFAAIDEDLLADWRERKTQNSWFEFTPHHAGYPALGAYVPITEFGSRFENGKLVKSEPERDLTFLRGLWGSAFADIKEIKNYILNYFRNPFGKLKFIEGPVTYSEAPRMNVDAMLLDLVMAYFTDMNDPSIKDKLCALQQALGTETDEFGIEMAEIIQNWNETSAEKKEQFLDHLLDRFKKTQEDTTTYSLMNWNTGLVWDRCVFVNETRKCVSKWQWGTVYNFLYKHGKIADETMCSRELLHLVDAGFAINTPYPLVLPPVRETHLILSFDFSAG-----DPLETIRATADYCQRHEIPFPEVSEDQLKEWAKAPASCYVLRG----ETGPVVMHFTLFNKDNCGDDIETWRKKYGTVKLSDSYTPDLVRDLLRVSKENVKKNKINILSEMRKVAGNPGNIPRVNKEACLGDRVKDPQGSQTVEFKKSHNISKD--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UP65-1", "uniprot_id": "PA24C_HUMAN", "id": "Q9UP65-1", "name": "Cytosolic phospholipase A2 gamma", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSSEVSIIPGLQKEEKAAVERRRLHVLKALKKLR--------IEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQGLLDAVTYLAGVSGSTWAISSLYTN----DGDMEALEADLKHRFTRQEWDLAKS-------LQKTIQAARSENYSLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWGSALGNTEVIREYIFDQLRN-LTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPPP----------EDEGGEPEHT--WLTEMLENWTRTSLEKQE-----------QPHEDPE-------RKGSLSNLMDFVKKTGICASKWEWGTTHNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAG-----DPFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKG----ETGPVVMHFPLFNIDACGGDIEAWSDTYDTFKLADTYTLDVVVLLLALAKKNVRENKKKILRELMNVAG-----------------LYYPKDS-----ARSCCLA----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08108-1", "uniprot_id": "PLB3_YEAST", "id": "Q08108-1", "name": "Lysophospholipase 3", "aln": "---------------------------------------------------------------------------MIRPLCSKIIISYIFAISQFLLAANAWSPTDSYVPGTVSCPDDINLVREATSISQNESAWLEKRNKVTSVALKDFLTRATAN---FSDSSEVLSKLFNDGNSENLPKIAVAVSGGG-YRSMLTGAGVLAAMDNRTEGAYEHGLGGLLQSTTYLSGASGGNWLVG------------------------------------------------------------------------------------------------------------------------------TLALNNWTSVQDILNNMQNDDSIWDLSDSIVTPGGIN---IFKTAKRWDHISNAVESKQNADYNTSLADIWGRALAYNFFPSLNRGGIGLTWSSIRDFPVFQNAEMPFPISVADGRYPGTKVINLNATVFEFNPFEMGSWDPSLNSFANVKYLGTNVSNGVPLERGKCTAGFDNAGFIMGTSSTLFNQFLLRINSTHLPSFITRLARHFLKDLSQDFNDIAVYSPNPFKDTKFLDSDYTTSIVDSDSLFLVDGGEDDENVPVLPLIQK--------------------------------ERDVDIIFAVDNSADMR------------LAWPDGSSLVHTYERQFVKQGQG---------------MSFPYVPDTNTFVN------LGLNKKP--TFFGCDAN--------NLTDLQYIPPLVVYLPNAEYSFNSNQSAFKLSYSESQRRSMIQNGFEIA------TRNNFTDDPEFMGCVGCAIIRRKQQALNITLPPECETCFKNYCWNGTLDTTPLPDVEKDVHHSFINVNSFNSSIGQEESLYAGSSASQSSSSSSSSSSSSEIPSATATLEKKAATN-----SGSHLSGISVKFSAMIMLTLLMFTGAV-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :. . : : : : . .* : : . . . . . : . . . . . : : :. . . : . .:.: . : : . . . . . : : . : : . :: .: : : : : . . . . . . ", "identical_positions": 1, "similar_positions": 64, "identity": "0.1%" }, { "cls_id": "homologset.agr.SGD:S000005372", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C0S6-1", "uniprot_id": "H2AZ_MOUSE", "id": "P0C0S6-1", "name": "Histone H2A.Z", "aln": "MAG---GKAGKDSGK--AKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKG------QQKTV-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C0S5-1", "uniprot_id": "H2AZ_HUMAN", "id": "P0C0S5-1", "name": "Histone H2A.Z", "aln": "MAG---GKAGKDSGK--AKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKG------QQKTV-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0C0S7-1", "uniprot_id": "H2AZ_RAT", "id": "P0C0S7-1", "name": "Histone H2A.Z", "aln": "MAG---GKAGKDSGK--AKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKG------QQKTV-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q71PD7-1", "uniprot_id": "H2AV_DANRE", "id": "Q71PD7-1", "name": "Histone H2A.V", "aln": "MAG---GKAGKDSGK--AKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKG------QQKTA-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q71UI9-1", "uniprot_id": "H2AV_HUMAN", "id": "Q71UI9-1", "name": "Histone H2A.V", "aln": "MAG---GKAGKDSGK--AKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKG------QQKTA-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3THW5-1", "uniprot_id": "H2AV_MOUSE", "id": "Q3THW5-1", "name": "Histone H2A.V", "aln": "MAG---GKAGKDSGK--AKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKG------QQKTA-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08985-1", "uniprot_id": "H2AV_DROME", "id": "P08985-1", "name": "Histone H2A.v", "aln": "MAG---GKAGKDSGK--AKAKAVSRSARAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKEETVQDPQRKGNVILSQAY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12692-1", "uniprot_id": "H2AZ_YEAST", "id": "Q12692-1", "name": "Histone H2A.Z", "aln": "MSGKAHGGKGKSGAKDSGSLRSQSSSARAGLQFPVGRIKRYLKRHATGRTRVGSKAAIYLTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGDDELDSLIRATIASGGVLPHINKALLLKVE------KKGSKK------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* * **...* .. :: * * ***********:*:** ::*.: ***:.**:* :*:***************:********************:******:****.***:***:*:*: * :: ", "identical_positions": 84, "similar_positions": 29, "identity": "57.53%" }, { "cls_id": "homologset.agr.SGD:S000005373", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FG68-1", "uniprot_id": "F7FG68_RAT", "id": "F7FG68-1", "name": "E3 ubiquitin-protein ligase synoviolin", "aln": "------MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKVMGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLAEDRVDFMER----SPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTR------GASVQLVFGFEYAILMTMVLTIFIKYVLHSVDLQ-SENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTFPLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGAPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAAAPPSTS-AATSRPSGAATTTAAGTSTSAP-----ASGSVPGPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLA--SLGPPRPATSVNPTEETASTVVSATPSTSVPSSEAPAPSLGASPPIPEAEKPPAPESVST------AEELP----------------EDGEPDAAELRRRRLQKLESPVAH------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBY1-1", "uniprot_id": "SYVN1_MOUSE", "id": "Q9DBY1-1", "name": "E3 ubiquitin-protein ligase synoviolin", "aln": "------MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKVMGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLAEDRVDFMER----SPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTR------GASVQLVFGFEYAILMTMVLTIFIKYVLHSVDLQ-SENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTFPLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAVDNVCIICREEMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPQPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAAAPPPTS-TAVSRPSGAATTTAAGTSTSAP-----APGSVPGPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLA--SLGPPRPATSVNPTEETASTVVSAAPSTSAPSSEAPTPSPGASPPIPEAEKPPAPESVGI------VEELP----------------EDGEPDAAELRRRRLQKLESPVAH------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86TM6-1", "uniprot_id": "SYVN1_HUMAN", "id": "Q86TM6-1", "name": "E3 ubiquitin-protein ligase synoviolin", "aln": "------MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKVMGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLAEDRVDFMER----SPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTR------GASVQLVFGFEYAILMTMVLTIFIKYVLHSVDLQ-SENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTFPLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLA--SLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVG-------TEEMP----------------EDGEPDAAELRRRRLQKLESPVAH------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803I8-1", "uniprot_id": "SYVN1_DANRE", "id": "Q803I8-1", "name": "E3 ubiquitin-protein ligase synoviolin", "aln": "------MVRAALVTATSLALTGAVVAHAYFLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKLMRKVFFGQLRAAEMEHLIERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLAEDRVDFMER----SPNISWVFHFRVLSLMVLLGVMDFLFVNHACHSIITR------GASVQLVFGFEYAILMTMVLTTFIKYTLHTIDLQ-SENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTFPLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEDLQATDNVCIICREEMVTGAKKLPCNHIFHSSCLRSWFQRQQTCPTCRMDVLRASQPNQTPAPP-AAQAPAPPAPANAPIPP-PVNVAPGMIPQFPPGLFPFW---GPFPGAPPPAVPGAPAAPTDTP-QPSSDGAQGAESGAGGLAQSTAEAASAAPGAMPGFPFTMPPPFPSAP-WLPMPPPPPFMSS-MPPPPSSLSSMSEAELRELEQEGRRGLEARLQCLHNIHTLLDAAMLNIHHYLSTVA--TLSPPRSETNTGETSESANVESSPSTANTETAGQEIQSQSGESINGAAGFSQPDSTTEGEK---DVKEEDE----------------DDGEPSAAELRRRRLRKLETTNTPDHGNLLKLASVN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q95SP2-1", "uniprot_id": "HRD1_DROME", "id": "Q95SP2-1", "name": "E3 ubiquitin-protein ligase HRD1", "aln": "--------MQLLLSSVCMALTSAVIGFAYYQKQQFYPAVVYITKSNASMGVIYIQFFVIVFMFGKLLSKIFLGTLRAAEFEHLLERFWYALTETCLAFTVFRDDFNPRFVALFTVLLFLKSFHWLAEERVDFMER----SPVLGWLFHIRVGSLLTVLGILDYVLLIHAYNSTLVR------GPTVQLVFGFEYAILLTVIASTAIKYVLHAAEMR-TDTPWENKAVFLLYTELVIGLIKVVLYILFVVIMAKIYALPMFVFRPMFFTIRNFRKALNDVIMSRRAIRNMNTLYPDATPEELRQSDNICIICREDMVNHSKKLPCGHIFHTTCLRSWFQRQQTCPTCRLNILRTPTVNSTAMPRQGDEAVAAAAGN--PIPAAAGVQPAGGVP----------------PPAPTAVVDGNQARADVNVAGGQALPPNFADLFGDASGLPNG------LPNLAGLQIPPPPVMPMISPFMIPPHFGYLTPLPPPPIPQDLTNFTDEELRAMEGLQRDHIVQRLKLLQNINLMLDSAGIMMSQYQSLSARLQLTAVTPATAVNGSADSSVYDMPSTSATAMAQLETHQVTPTAAASSASPTMPAEKVTIEDLGADADEDDIPSTATEAVSIPNSDADFEENSSELGELRKRRLKFLEERNKSAATNERTTAE--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08109-1", "uniprot_id": "HRD1_YEAST", "id": "Q08109-1", "name": "ERAD-associated E3 ubiquitin-protein ligase HRD1", "aln": "MVPENRRKQLAIFVVVTYLLTFYCVYSATKTSVSFLQVTLKLNEG-FNLMVLSIFILLNSTLLWQLLTKLLFGELRLIEHEHIFERLPFTIINTLFMSSLFHERYFFTVAFFGLLLLYLKVFHWILKDRLEALLQSINDSTTMKTLIFSRFSFNLVLLAVVDYQIITRCISSIYTNQKSDIESTSLYLIQVMEFTMLLIDLLNLFLQTCLNFWEFYRSQQSLSNENNHIVHGDPTD-----------ENTVESDQSQPVLNDDDDDDDDDRQFTGLEGKFMYEKAIDVFTRFLKTALHLSMLIPFRMPMMLLKDVVWDILALYQSGTSLWKIWRNNKQLDDTLVTVTVEQLQNSANDDNICIICMDELIHS----------------------------------------PNQQTWKNKNKKPKRLPCGHILHLSCLKNWMERS---------------QTCPICRLPVFDEKGNVVQTTFTS----------NSDITTQTTVTDSTGIATDQQGFANEVDLLPTRTTSPDIRIVPTQNIDTLAM-------RTRSTSTPSPTWYTFPLHKTGDNSVGSSRSAYEFLITNSDEKENGIPVKLTIEN--------HEVN-----------------SLHGDGGEQIAKKIVIPDKFIQHI-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . ** : * . .* ..: :.:. .: *: * :: :: ::: *:::* ** * **::** ::: :* : ::*:: : .. : :**:** ***: ::*:: : : *. : ::. *. : :*.::*: :: :. * .. ..:: *: :*:::*: : . :: *: :: :: . .*: .::: : : . : *:: . ..: . :* .:** :. : * .: .: :: :::* * . . *. * ::* * :: *: . .. : . * * : : . .:: : : : .:. * . * : : : . : : : .: . .: . . .* ::: : ", "identical_positions": 52, "similar_positions": 165, "identity": "7.75%" }, { "cls_id": "homologset.agr.SGD:S000005376", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYK9-1", "uniprot_id": "KCC1B_MOUSE", "id": "Q9QYK9-1", "name": "Calcium/calmodulin-dependent protein kinase type 1B", "aln": "--------------------------------------------------------------------------------------MLLLKKQTEDISSVYEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRG---KEALVENEIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGN---MLGTACGTPGYVAPELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPE--------LFSQILRASY--EFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALQHLWISGDAAFD--RDILGSVSEQIQKNFARTHWKRAFNATSFLRHIRKLGQSP---------------------------EGEEASRQ--------------------------------------------------------------------------------CMTRHS-----------------------------------------------------------------------HPGLGTSQSPKW------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70150-1", "uniprot_id": "KCC1B_RAT", "id": "O70150-1", "name": "Calcium/calmodulin-dependent protein kinase type 1B", "aln": "--------------------------------------------------------------------------------------MLLLKKQTEDISSVYEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRG---KEALVENEIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGN---MLGTACGTPGYVAPELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPE--------LFSQILRASY--EFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALQHLWISGDAALD--RDILGSVSEQIQKNFARTHWKRAFNATSFLRHIRKLGQSP---------------------------EGEEASRQ--------------------------------------------------------------------------------GMTRHS-----------------------------------------------------------------------HPGLGTSQSPKW------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P2M8-1", "uniprot_id": "KCC1B_HUMAN", "id": "Q6P2M8-1", "name": "Calcium/calmodulin-dependent protein kinase type 1B", "aln": "--------------------------------------------------------------------------------------MLLLKKHTEDISSVYEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRG---KEALVENEIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGN---MLGTACGTPGYVAPELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPE--------LFSQILRASY--EFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALRHLWISGDTAFD--RDILGSVSEQIRKNFARTHWKRAFNATSFLRHIRKLGQIP---------------------------EGEGASEQ--------------------------------------------------------------------------------GMARHS-----------------------------------------------------------------------HSGLRAGQPPKW------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91VB2-1", "uniprot_id": "KCC1G_MOUSE", "id": "Q91VB2-1", "name": "Calcium/calmodulin-dependent protein kinase type 1G", "aln": "------------------------------------------------------------------------------MGRKEEEDCSSWKKQTTNIRKTFIFMEVLGSGAFSEVFLVKQRVTGKLFALKCI-KKSPAF---RDSSLENEIAVLKRIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNG---VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESK--------LFEKIKEGYY--EFESPFWDDISESAKDFICHLLEKDPNERYTCEKALRHPWIDGNTALH--RDIYPSVSLQIQKNFAKSKWRQAFNAAAVVHHMRKLHMNL---------------------------HSPSVRQEVENRPPVSPAPEVSRPDSHDSSITEAPILDPSTPLPALTRLPCSHSSRPSAPSGGRSLNCLVNGSLRISSSLVPMQQGPLATGPCGCCSSCL------------------------------------------------------------NIGNKGKSSYCSEPTLFRKANKKQNFKSEVMVPVKAGGSTH--------------CRGGQTGVCLVM----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TNJ7-1", "uniprot_id": "KCC1G_RAT", "id": "Q7TNJ7-1", "name": "Calcium/calmodulin-dependent protein kinase type 1G", "aln": "------------------------------------------------------------------------------MGRKEEEDCSSWKKQTTNIRKTFIFMEVLGSGAFSEVFLVKQRVTGKLFALKCI-KKSPAF---RDSSLENEIAVLKRIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNG---VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESK--------LFEKIKEGYY--EFESPFWDDISESAKDFICHLLEKDPNERYTCEKALRHPWIDGNTALH--RDIYPSVSLQIQKNFAKSKWRQAFNAAAVVHHMRKLHMNL---------------------------HSPSVRQEVENRPPVSPAPEVSRPGSHDSSITEAPILDPSTPLPALTRLPCSHSSRPSAP-GGRSLNCLVNGSLRISSSLVPMQQGPLATGPCGCCSSCL------------------------------------------------------------NIGNKGKSSYCSEPTLFRKANKKQNFKSEVMVPVKAGGSTH--------------CRAGQTGVCLIM----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96NX5-1", "uniprot_id": "KCC1G_HUMAN", "id": "Q96NX5-1", "name": "Calcium/calmodulin-dependent protein kinase type 1G", "aln": "------------------------------------------------------------------------------MGRKEEDDCSSWKKQTTNIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCI-KKSPAF---RDSSLENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNG---IMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESK--------LFEKIKEGYY--EFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWIDGNTALH--RDIYPSVSLQIQKNFAKSKWRQAFNAAAVVHHMRKLHMNL---------------------------HSPGVRPEVENRPPETQASETSRPSSPEITITEAPVLDHSVALPALTQLPCQHGRRPTAP-GGRSLNCLVNGSLHISSSLVPMHQGSLAAGPCGCCSSCL------------------------------------------------------------NIGSKGKSSYCSEPTLLKKANKKQNFKSEVMVPVKASGSSH--------------CRAGQTGVCLIM----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PSZ5-1", "uniprot_id": "A0A8M9PSZ5_DANRE", "id": "A0A8M9PSZ5-1", "name": "", "aln": "-------------------------MSVSLRSAQFPLPSHVILCHCCPCLRLDSFCKRQKSCWSCYRPEEIPVEAHAEMGRKEGE--YEWKKSTDNIQDVFDFMDVLGSGAFSEVFMVKERKTGKLFAMKCV-KKK-NK---RDINLENEIAVLRKIKHENVVCLEDFYESRTHYYLVMQLVSGGELFDRILDRGMYSEMDASSVIRQVLEAVSYLHNNGIVHRDLKPENLLYYSPDENSKIMISDFGLSKMEDNG---VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETETR--------LFSKIMKGQY--EFDSPFWDDISDSAKDFIRNMMQKNPKMRFNTEQALRHPWIIGKTARS--QDIYHSVSEQMQKNFAKSKWKQAFNATVAINHMKKLQQAH---------------------------SEACVRLKDSPR-----------------DVPEIKVIASSTPESVRKKLLSETP----EPNGSMNVPC---GSTEAKSQYHPMRVSHSETTHVG----TL------------------------------------------------------------TIAEKGKHVYHSEPADLNGYAKR-------------SSNRP--------------GQNLQTGVCSVM----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q91YS8-1", "uniprot_id": "KCC1A_MOUSE", "id": "Q91YS8-1", "name": "Calcium/calmodulin-dependent protein kinase type 1", "aln": "--------------------------------------------------------------------------------MPGAVEGPRWK-QAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALEG---KEGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGS--VLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAK--------LFEQILKAEY--EFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALD--KNIHQSVSEQIKKNFAKSKWKQAFNATAVVRHMRKLQLGT---------------------------SQEGQGQ-----------------------------------TGSHGELLTP--------------------TAGGPAAGCCCRD--CCVEPGS---------------------------------------------------------------------ELPPAPPPSSRAMD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63450-1", "uniprot_id": "KCC1A_RAT", "id": "Q63450-1", "name": "Calcium/calmodulin-dependent protein kinase type 1", "aln": "--------------------------------------------------------------------------------MPGAVEGPRWK-QAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALEG---KEGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGS--VLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAK--------LFEQILKAEY--EFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALD--KNIHQSVSEQIKKNFAKSKWKQAFNATAVVRHMRKLQLGT---------------------------SQEGQGQ-----------------------------------TASHGELLTP--------------------TAGGPAAGCCCRD--CCVEPGS---------------------------------------------------------------------ELPPAPPPSSRAMD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14012-1", "uniprot_id": "KCC1A_HUMAN", "id": "Q14012-1", "name": "Calcium/calmodulin-dependent protein kinase type 1", "aln": "--------------------------------------------------------------------------------MLGAVEGPRWK-QAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEG---KEGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGS--VLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAK--------LFEQILKAEY--EFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALD--KNIHQSVSEQIKKNFAKSKWKQAFNATAVVRHMRKLQLGT---------------------------SQEGQGQ-----------------------------------TASHGELLTP--------------------VAGGPAAGCCCRD--CCVEPGT---------------------------------------------------------------------ELSPTLPHQL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UVK7-1", "uniprot_id": "A0A8N7UVK7_DANRE", "id": "A0A8N7UVK7-1", "name": "", "aln": "--------------------------------------------------------------------------------MPLGEDENGWKKKTTDIKENYDFKEVLGTGAFSEVFLAEEKKTQRLVAIKCIPKKALEG---KENSIENEIAVLHRIKHENIVSLEDIFESQSHLYLVMQLVSGGELFDRIVEKGFYTERDASKLIRQILDAVKYLHDMGIVHRDLKPENLLYYSMEEDSNIMISDFGLSKIEDSGS--VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVISYILLCGYPPFYDENDAK--------LFEQILKAEY--EFDSPYWDDISDSAKDFISHLMEKDPSLRYTCEQALLHPWISGDTALD--KNIHESVSAQIKKNFAKSKWKQAFNATAVVRHMRRLQLST---------------------------SLEGPSQI-------------------------------TSTSPYR-HLLLPAKELDQRD-------EEEEEEEEEEENGSPSVDGRRGSADRD---------------------------------------------------------------------SLRSCAYCCRPTSRI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F1H0-1", "uniprot_id": "E7F1H0_DANRE", "id": "E7F1H0-1", "name": "", "aln": "--------------------------------------------------------------------------------MPLGEDGPSWKKKTANIKDIYDFKEVLGTGAFSEVMLAEEKRTRKLVAVKCIAKKALEG---KENSIENEIAVLHKIKHANIVSLEDIFESKSHLYLVMQLVSGGELFDRIVEKGFYTEKDASKLIQQILDAVKYLHDMGIVHRDLKPENLLYYSMDEESKIMISDFGLSKIEGSGS--VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAK--------LFEQILRAEY--EFDSPYWDDISDSAKDFIVHLMEKDPNQRYTCEQALQHPWIAGDTALD--KNIHESVSAQIKKNFAKSKWKQAFNATAVVRHMRRLQLGT---------------------------SQEGPPQN-------------------------------TLPSPCHGHLLLP---------------EGDEDDSVRENSGCS-----EGVSDGN---------------------------------------------------------------------DIQNCSYHLHPTSRV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6AUH0-1", "uniprot_id": "A0A8I6AUH0_RAT", "id": "A0A8I6AUH0-1", "name": "calcium/calmodulin-dependent protein kinase", "aln": "------------------------------------------------------------------------------MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKG---KESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGD--VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSK--------LFEQILKAEY--EFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALS--KNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRRLQLGS---------------------------SLDSSNAS----------------------------------VSSNLSLASQ-------------------KDCLAPSTLCSFLSSSSGVAGVG---------------------------------------------------------------------AERRPRPTTVTTGHTGSK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BW96-1", "uniprot_id": "KCC1D_MOUSE", "id": "Q8BW96-1", "name": "Calcium/calmodulin-dependent protein kinase type 1D", "aln": "------------------------------------------------------------------------------MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKG---KESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGD--VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSK--------LFEQILKAEY--EFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALS--KNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRRLQLGS---------------------------SLDSSNAS----------------------------------VSSNLSLASQ-------------------KDCLAPSTLCSFLSSSSGVAGVG---------------------------------------------------------------------AERRPRPTTVTTGHTGSK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IU85-1", "uniprot_id": "KCC1D_HUMAN", "id": "Q8IU85-1", "name": "Calcium/calmodulin-dependent protein kinase type 1D", "aln": "------------------------------------------------------------------------------MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKG---KESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGD--VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSK--------LFEQILKAEY--EFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALN--KNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGS---------------------------SLDSSNAS----------------------------------VSSSLSLASQ-------------------KDCLAPSTLCSFISSSSGVSGVG---------------------------------------------------------------------AERRPRPTTVTAVHSGSK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7URA4-1", "uniprot_id": "A0A8N7URA4_DANRE", "id": "A0A8N7URA4-1", "name": "", "aln": "------------------------------------------------------------------------------------MPLLRDLRKKDDINAVYELKEKLGEGSFSEVRVAQHRCTQKLVAVKCIRKRALKG---KESMLENEVAVLRRINHENIVSLEETFETPTKLYLVMTLLTGGELLNRILERGSYTEKDASRVIYQVLQAVKYLHQLGVVHRDLKPENLIFETPLEDSKIVISDFGLSKMEEQG---ALSTACGTPAYVAPELLQQKTYGKEVDLWAIGVITFILLCGYPPFYDDNDTQ--------LYKLIIKAEY--EFDSPYWNDISDSAKDFIVHLLQKDPAKRFNCEQASQHPWISGGAALD--RNIHGSVSAQIQKNFAKSHWKRAFNATIIVHHLTKKAHPG---------------------------EDDEGNQS-------------------------------------------------------------------------------TSIGNI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3UHL1-1", "uniprot_id": "CAMKV_MOUSE", "id": "Q3UHL1-1", "name": "CaM kinase-like vesicle-associated protein", "aln": "----------------------------------------------------------------------------MPFGCVTLGDKKNYN-QPSEVTDRYDLGQVIKTEEFCEIFRAKDKTTGKLHTCKKFQKRDGRK---VRKAAKNEIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENGL----IKEPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDY--EFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEWISGNAASD--KNIKDGVCAQIEKNFARAKWKKAVRVTTLMKRLRAPEQSGTAATQSA--SDAATPGAAGGAIAAAAAAAAAGGAASASGASATAATEGGAGCAAKSDD-IASADRSATPATDGSATPATDGSVTPATDGSITPATDGSVTPATDRSATPATDGR--ATPATEESTVP---------------------------------------------------------------ATQSSALPAAKAAATPEPAVAQPDSTALEGATGQAPP---------------SSKGEEATGCAQESQRVETS--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63092-1", "uniprot_id": "CAMKV_RAT", "id": "Q63092-1", "name": "CaM kinase-like vesicle-associated protein", "aln": "----------------------------------------------------------------------------MPFGCVTLGDKKNYN-QPSEVTDRYDLGQVVKTEEFCEIFRAKDKTTGKLHTCKKFQKRDGRK---VRKAAKNEIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENGL----IKEPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDY--EFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEWISGNAASD--KNIKDGVCAQIEKNFARAKWKKAVRVTTLMKRLRAPEQSGTAAT-----SDAATPGAAGG-----AVAAAAGGAAPASGASATVGTGGDAGCAAKSDD-MASADRSATPATDGSATPATDGSVTPATDGSITPATDGSVTPATDRSATPATDGR--ATPATEESTVP---------------------------------------------------------------AAQSSAAPAAKAAATPEPAVAQPDSTALEGATGQAPP---------------SSKGEEATGCAQESQRVETS--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NCB2-1", "uniprot_id": "CAMKV_HUMAN", "id": "Q8NCB2-1", "name": "CaM kinase-like vesicle-associated protein", "aln": "----------------------------------------------------------------------------MPFGCVTLGDKKNYN-QPSEVTDRYDLGQVIKTEEFCEIFRAKDKTTGKLHTCKKFQKRDGRK---VRKAAKNEIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENGL----IKEPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDY--EFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEWISGNAASD--KNIKDGVCAQIEKNFARAKWKKAVRVTTLMKRLRAPEQSSTAAAQSASATDTATPGAAGG-----ATAAAASGATSAP--------EGDAARAAKSDN-VAPADRSATPATDGSATPATDGSVTPATDGSITPATDGSVTPATDRSATPATDGR--ATPATEESTVP---------------------------------------------------------------TTQSSAMLATKAAATPEPAMAQPDSTAPEGATGQAPP---------------SSKGEEAAGYAQESQREEAS--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SY49-1", "uniprot_id": "CAMKV_DANRE", "id": "Q7SY49-1", "name": "CaM kinase-like vesicle-associated protein", "aln": "----------------------------------------------------------------------------MPFGCLKPGEKKDYN-SPTEITDKYDLGQIVKSEEFCEIFRAKDKNTLKMYTCKKFLKKDGRK---VRKAAKNEIVILKMVKHPNILQLVDVYETRKEYYLFLELATGREVFDWILDQGYYSERDTSNVIRQVMEAVAYLHSLKIVHRNLKLENLVYYNRLKHSKIVISDFHLAKLENGL----IKEPCGTPEYLAPEVVGRQRYGRPVDCWALGVIMYILLSGNPPFYDEADDDDYENHDKNLFRKILAGDY--EFDSPYWDEISDSAKNLVSRLMEVDQDQRLTAQEAINHEWISGNAASD--KNIKENVCAQIEKNFAKAKWKKAVRVTTMMKRLRAPENQTAAAT---------------------APAAEAAAAS--P---------------SEADP-AAGAQETPQAASEASTAPS-------STAESLSASIE-----------VPAVE------PANAEAASA---------------------------------------------------------------AVQP---PAEPVVHVPEPEQPVPTS----RCNGEASA---------------LDTVEEQSG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3ANJ4-1", "uniprot_id": "A0A8M3ANJ4_DANRE", "id": "A0A8M3ANJ4-1", "name": "CaM kinase-like vesicle-associated protein", "aln": "----------------------------------------------------------------------MRVDAVMPFGCLALRDGRTYN-SLSDITDKYEIGQVLKAKEFCELCLVKERQTDKVYVCKKFLKKDGRK---VRKAAKNEIMILKMVKHPNILQLIDAFETRKEFFIIQELATGGDVFDWILDQGNYTERDAANVIRQVLEAVAYLHSLNIVHRNLKLENLMYYRESNHNKVVLRDFYLSRFENGS----ITEPCGTPEYLAPEVVARHRYGRPVDCWAVGVIMYILLSGNPPFYDETEEENTDMHNRIIFCRIVGGEF--EFDSPYWDDISPAAKELVCRFMEVDQMLRITAQDALTHEWIAGNGASE--KNLKEGVCAQFEKNFAKAKWRKAIRVTTFMQRLRATDIGSSDGAVEGQAEGVKADGLDGKGIQTDSGGVSAGSVSHEVSVESRPTENQEAGQTKVEEKETETVGQSNSSLKIQAEEPLNKKETTEGTSEIKDKPTTGANQKAASVQPIKTSDSRENSIPVEPEATTLGSVEKKSPFHDTPNRRKIAANLSMDHSSCSEAKTATLSTGNEPPLQSEDKKDTVHDMTASSWCQTQLPEAVAERSAEVGAPSEVNPKSKELKKGRADKGSQSVKNIQSVYAGLGSSSLGQDQTVFVQELQEMVHGASGYGSPYCPTYSVGQYGGLDPGSAASADWQMDCVIEQIEKQMAAVLEKIEGDMPSLLEQISDHPETLPRAKSASSSPSPRPRSYHHSTPPPLPTTPRPVMPSLPHLTIPPPSYPPPSPPSQIQGHSHPAPEESTSDGQKSTKRSGQSPRGSVSGKGL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q91YA2-1", "uniprot_id": "KPSH1_MOUSE", "id": "Q91YA2-1", "name": "Serine/threonine-protein kinase H1", "aln": "MGCGTSKVLPEPPKDVQLDLVKKVEPFSGTKNDVYKHFITEVDSVGPLKAGFP---ATSQYAPPCPGVPNTGHTAPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREG---RE-VCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTR--------LYRQILRGKY--SYLGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSSQSTRSSRSTRSNKSR---------------------------RVRERELR-------------------------------------------------------------------------------------------------------------------------------------------------------------ELNLRYQQQYNG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ABY1-1", "uniprot_id": "D4ABY1_RAT", "id": "D4ABY1-1", "name": "Serine/threonine-protein kinase H1", "aln": "MGCGTSKVLPEPPKDVQLDLVKKVEPFSATKNDVYKHFITEVDSVGPLKAGFP---ATSQYAPPCPGAPTTGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREG---RE-VCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTR--------LYRQILRGKY--SYLGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSSQSTRSSRSTRSNKSR---------------------------RVRERELR-------------------------------------------------------------------------------------------------------------------------------------------------------------ELNLRYQQQYNG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11801-1", "uniprot_id": "KPSH1_HUMAN", "id": "P11801-1", "name": "Serine/threonine-protein kinase H1", "aln": "MGCGTSKVLPEPPKDVQLDLVKKVEPFSGTKSDVYKHFITEVDSVGPVKAGFP---AASQYAHPCPGPPTAGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREG---RE-VCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTR--------LYRQILRGKY--SYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSAQSTRSSRSTRSNKSR---------------------------RVRERELR-------------------------------------------------------------------------------------------------------------------------------------------------------------ELNLRYQQQYNG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q501V0-1", "uniprot_id": "KPSH1_DANRE", "id": "Q501V0-1", "name": "Serine/threonine-protein kinase H1 homolog", "aln": "MGCRTSKVLPEPPGDVQLDLVKKVEPH---QTDVYKNFIKYDG--GGEKTGSPSPQGQSQAVAKVSQSPPPANDQPEPADSHRKKVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRSTRQPYAIKMIETRYREG---RE-VCESELCVLRRVRHTNIIQLMEVFETAERVYMVMELATGGELFDRIITRGSFTERDATRVLQMVLDGVKYLHTLGITHRDLKPENLLYYHPGADSKIMITDFGLASTRKKGDECLMKTTCGTPEYIAPEILVRKPYTNAVDMWALGVISYILLSGTMPFEDDNRMR--------LYRQILKGKY--SFSGEPWPSVSNLAKDFIDRVLTVDPNERLSAGQALKHPWIVSMAASSSMKNLHRSISQNLLKRASSRCHSTKSSQSTRSSRSTKSSKAR---------------------------RLREKELR-------------------------------------------------------------------------------------------------------------------------------------------------------------ELNRRYQQQCNG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08414-1", "uniprot_id": "KCC4_MOUSE", "id": "P08414-1", "name": "Calcium/calmodulin-dependent protein kinase type IV", "aln": "------------------------------------------------------MLKVTVPSCPSSPCSSVTAS----TENLVPDYWIDGSNRDP-LGDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTV------DKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDARDAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQV--LMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQ-------FMFRRILNCEY--YFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQHPWVTGKAANF---VHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHTSIQ------------------ENHKASSDPPSTQDAKD------------------------STDLLGKKMQEEDQEEDQ-------------VEAEASADEMRKLQSEEVEKDAGVKEEE----------------------------------------------------------------------TSSMVPQDPEDELETDDPEMKR-DSEEKLKSVEEEMDPMTEEEAPDAGLGVP-QQDAIQPEY----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13234-1", "uniprot_id": "KCC4_RAT", "id": "P13234-1", "name": "Calcium/calmodulin-dependent protein kinase type IV", "aln": "------------------------------------------------------MLKVTVPSCPSSPCSSVTSS----TENLVPDYWIDGSKRDP-LSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTV------DKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQV--LMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQ-------FMFRRILNCEY--YFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQHPWVTGKAANF---VHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHTNIQ------------------ESNKASSEAQPAQDGKD------------------------KTDPLENKMQAGDHEA-----------------AKAAADETMKLQSEEVEEEEGVKEEEEEEEE--------------------------------------------------------------EEETSRMVPQEPEDRLETDDQEMKR-NSEETLKSVEEEMDPKAEEEAAAVGLGVPPQQDAILPEY----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16566-1", "uniprot_id": "KCC4_HUMAN", "id": "Q16566-1", "name": "Calcium/calmodulin-dependent protein kinase type IV", "aln": "------------------------------------------------------MLKVTVPSCSASSCSSVTASAAPGTASLVPDYWIDGSNRDA-LSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTV------DKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQV--LMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQ-------FMFRRILNCEY--YFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVTGKAANF---VHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHGSIQ------------------ESHKASRDPSPIQDGNED----------------------MKAIPEGEKIQGDGAQA----------------AVKGAQAELMKVQALEKVKGADINAEE----------------------------------------------------------------------APKMVPKAVEDGIKVADLELEEGLAEEKLKTVEEAAAPREGQGSSAVGFEVP-QQDVILPEY----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RRA7-1", "uniprot_id": "A0A8M1RRA7_DANRE", "id": "A0A8M1RRA7-1", "name": "Calcium/calmodulin-dependent protein kinase type IV", "aln": "-----------------------------------------------------------MPTSRSDARP--------------VEYWVDGSRRDATVEDFYNMGPELGRGATSVVLRCEEKQTEKPYAVKVLKKTI------DKKIVRTEIGVLLRLSHPNIIRLKEIFETETEIFLILELVTGGELFDRIVERGYYSERDAAHVIKQILEAVAYLHENGVVHRDLKPENLLYADLSIDAPLKIADFGLSKIIDEQV--TMKTVCGTPGYCAPEILRGNAYGPEVDMWSVGVILYILLCGFEPFFDQRGDQ-------YMYSRILNCDY--EFVSPWWDEVSLNAKDLVNKLIVLDPHKRLTVKQALEHPWVLGKAARF---SHMDTTQRKLQEFNARRKLKAAMKAVVATSRMHEGSRRRTDSC------------------EMP--NTDKTSCQ----------------------------------SSIQKENTTN------------------SSREPISMKEGSEQVADGALGPSSS----------------------------------------------------------------------TPQTTPKSKPFTQSGPVPTRPPLIAEGHRQTSVIPKAPVVRPREPKKSFSVEPGGKHEVS------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22517-1", "uniprot_id": "KCC2_YEAST", "id": "P22517-1", "name": "Calcium/calmodulin-dependent protein kinase II", "aln": "------------------------------------------------------MPKESEVINSEFHVDVQDPERLNGHPVAKFINKLSGQPESYVNRTNYIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEED-LIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSPFIAESVEG--------FMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPTATELLDDPWITSKRVET--SNILPDVKKGFSLRKKLRDAIEIVKLNNRIKRLRNMYSLGDDGD----------------------NDIEENSLN------------------------------------------------------------------ESLLDGVTHSLDDLRLQSQK-----------------------------------------------------------------------KGGELTEEQMKLKSALTKDAFVQIVKAATKNKHKVLAGEEEDDSKKTLHDDRESKSED--------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : .. : . . * . . *: :* : * *:: : : . : . : * :* :::: *: :* ::* *: : :: .* *:* :.**:** **::: . : : ** :: : .*: * ***:: : * *::*:* : **.* ** : : : : * .:* .* :: . : : * . . . *: . . : : ", "identical_positions": 41, "similar_positions": 79, "identity": "4.88%" }, { "cls_id": "homologset.agr.SGD:S000005378", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z9R7-1", "uniprot_id": "D3Z9R7_RAT", "id": "D3Z9R7-1", "name": "Syntaxin-16", "aln": "MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHTTSSPLHSRSIAAELDELADDRMALVSGISLDPEAAIGVTKRSPPKWVDGVDEIQYDVGRIKQKMRELASLHDKHLNRPTLDDSSEEEHAIEITTQEVTQLFHRCQRAVQALPSRARR------TCSEQEERLLRNVVASLAQALQELSTSFRHAQSDYLKRMKNREERSQHFFDTP------------------------------VPLMD---------DGDDATLYGQG-------FTDDQLVLVEQ-NTLVVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCVKTEDGLKQLHKAEQYQKKNRKMLVILILVAVIVVLIVVLIAVKSR----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BVI5-1", "uniprot_id": "STX16_MOUSE", "id": "Q8BVI5-1", "name": "Syntaxin-16", "aln": "MATRRLTDAFLLLRNNSIQTRQLLAEQVSSHTTSSPLHSRSIAAELDELADDRMALVSGISLDPEAAIGVTKRSPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEVTQLFHRCQRAVQALPSRARR------ACSEQEERLLRNVVASLAQALQELSTSFRHAQSDYLKRMKNREERSQHFFDTP------------------------------VPLMD---------DGDDATLYGQG-------FTDDQLVLVEQ-NTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCVKTEDGLKQLHKAEQYQKKNRKMLVIVILVAVIIVLLVALVAVKSR----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14662-1", "uniprot_id": "STX16_HUMAN", "id": "O14662-1", "name": "Syntaxin-16", "aln": "MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLHSRSIAAELDELADDRMALVSGISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRAR-------ACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFDTS------------------------------VPLMD---------DGDDNTLYHRG-------FTEDQLVLVEQ-NTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIVVLVGVKSR----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BJE0-1", "uniprot_id": "A0A8M2BJE0_DANRE", "id": "A0A8M2BJE0-1", "name": "Syntaxin-16", "aln": "MATRRLTDAFLLMRNNAIQNRQILAEQVSTYDPRRTLNTRSNAA----LADDRMALVSGISLDPEAAIGVTKRLPPKWVEGVDEIQYEITRIRQKMKELASLHDKHMNRPTLDDSSEEEHAIEITTQEITQMFHRCQRAVTGLQTQSY-------HCTEQENRLLTNVVSSLAQSLQELSLNFRHTQSGYLKRMKNREERSKHFFDS-------------------------------GPLVE---------EDEDIALYDRG-------FTDDQLVLVQQ-NTVMVEEREREIRQIVQSISDLNEIFRDLAGMVVEQGTVLDRIDFNVEQSCVKTEEGLQQLQKAEQYQKKNRKMLVILILFVIVVVLILILFGTKFS----------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VR90-1", "uniprot_id": "Q9VR90_DROME", "id": "Q9VR90-1", "name": "", "aln": "MTSRNLTEVFVIMRNNASKNRNHYDDRRGSDAERLLKHSVREAEEGLELQDD-------------------YGTPPAWLDKFEEAQYTMSKIKPKLDELGSLHARHLLRPAFDDQRDDECDIEVLSQIVSKLITSTHRHIQCVRSSIG-------VGSKMEQCLTVNAVHCALLQLQELTVKFRASQNAYLLQLNSREERSQKYFDDGGGAGAGDVFTNVELGEQSAENFVDSFDNFLQPPAEGKSGNGYLFEDDEQAIDDHFQRPPASRMTQQQLLLFEEENTRVAQHREQEVTKIVKSIYDLNDIFKDLGHMVQEQGTVLDRIDYNVEQTQTRVSEGLRQLHKAEMYQRKNRKMCVILVLAAVTFFMLLLLILTKL-----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08144-1", "uniprot_id": "TLG2_YEAST", "id": "Q08144-1", "name": "t-SNARE affecting a late Golgi compartment protein 2", "aln": "-MFRDRTNLFLSYRRTFPHNITFSSGKAPLGDDQDIEMGTYPMMNMSHDISARLTDERKNKHEN-----HSDALPPIFIDIAQDVDDYLLEVRRLSEQLAKVYRKNS-LPGFEDKSHDEALIEDLSFKVIQMLQKCYAVMKRLKTIYNSQFVDGKQLSREELIILDNLQKIYAEKIQTESNKFRVLQNNYLKFLNKDDLKPIRNKASAEN----------------------------TLLLDDEEEEAAREKREGLDIEDYSKR-----TLQRQQQLHDTSAEAYLRERDEEITQLARGVLEVSTIFREMQDLVVDQGTIVDRIDYNLENTVVELKSADKELNKATHYQKRTQKCKVILLLTLCVIALFFFVMLKPHGGGSGGRNNGSNKYNNDDNKTVNNSHDDGSNTHINDEESNLPSIVEVTESENDALDDLL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *: *: *.. :. : . ** ::: :: : : .:: :*..:: :: * ::*. .:* ** : : ::: : : : :. * : * :* : .** *. ** ::. : :. : : . : : : * * : ..*:.*: ::.:.: ::. **::: :: :***::****:*:*:: . ... ::*:** **::.:* **::* . ::. :. ", "identical_positions": 44, "similar_positions": 103, "identity": "10.07%" }, { "cls_id": "homologset.agr.SGD:S000005381", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7EPZ4-1", "uniprot_id": "F7EPZ4_RAT", "id": "F7EPZ4-1", "name": "Exosome complex exonuclease RRP44", "aln": "----------MTSAAARRLARPVARRTRARPWSCSPGTRRAASAHGR--TTSCRTPMCCCTRCVDAGPRGDEGAWREGRRVSGWRGKFFGHPRFQLSRPGYLSLTLLHLLVVFGSWSRTFRHVNFLTPGVSSTLDYKCLEAGDLGFCGLQIATPRQLIDVLEDP-AIRNVIVLQTVLQEVRNRSAPIYKRIRDVTNNQE--KHFYTFTNEHHKETYIEQEQGENANDRNDRAIRVAAKWYNEHLK-MSAENQLQ--------VILITNDKKNKE---KAAEEGIPAFTCEEYVKSLTANPELIDRLACLS---DEMNEIESGKIIFSEHLPLSKLQQGIKSGSYLQGTFRASRENYLEATVWIHGDKEDEKEILIQGLKHLNRAIHEDIVAVELLPKSQWVAPSSVVLHDEGQNEDDVEKDE---------------------ERELLLKT--AVSEKMLRPTGRVVGIIKRNWRPYCGMLSKSDIK----ESRRHLFTPADKRIPRIRIETRQASALEGRRIIVAIDGWPRNSRYPNGHFVKNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLP------KMPWSITEEDMK-------NREDLRHLCVCSVDPPGCTDIDDALHCRELSNGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLRSNVDRLAFSCIWEMNHNAEILKTRFTKSVINSKASLTYAEAQMRIDSAAMNDDITTSLRGLNKLAKILKRGRIEKGALTLSSPEIRFHMDSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEVLVKAAKS-KNLEIRTDTAKSLADSLDRAECPDFPYLNTLLRILATRCMMQAVYFCSG--MDSDFHHYGLASPIYTHFTSPIRRYADIIVHRLLAVAIGADCTYPELTDKHKLSDICKNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFE-EKD--------KPKPRLTYDDEIPSLRIEGTVFHVFDKVKVKITLDSSNLQHQKIRMALVEPQIPGINMPPDVSDMD----LNGPGGKKRKLEK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CSH3-1", "uniprot_id": "RRP44_MOUSE", "id": "Q9CSH3-1", "name": "Exosome complex exonuclease RRP44", "aln": "----------------MLRSKTFLKKTRAG------GVVKIVREHYLRDDIGCGAPACSACGGAHAGPALELQPRDQASSLCPWP--------------------------------------HYLLPDTN---------------------VLLHQIDVLEHP-AIRNVIVLQTVMQEVRNRSAPIYKRIRDVTNNQE--KHFYTFTNEHHKETYIEQEQGENANDRNDRAIRVAAKWYNEHLKRVAADSQLQ--------VILITNDRKNKE---KAVQEGIPAFTCEEYVKSLTANPELIDRLAYLS---DEMNEIESGKIIFSEHLPLSKLQQGIKSGSYLQGTFRASRENYLEATVWIHGDKEEEKEILIQGIKHLNRAVHEDIVAVELLPRSQWVAPSSVVLDDEGQNEDDVEKDE---------------------ERELLLKT--AVSEKMLRPTGRVVGIIKRNWRPYCGMLSKSDIK----ESRRHLFTPADKRIPRIRIETRQASALEGRRIIVAIDGWPRNSRYPNGHFVKNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLP------RMPWSITEEDMK-------NREDLRHLCVCSVDPPGCTDIDDALHCRELSNGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLRSNVDRLAFSCIWEMNHNAEILKTRFTKSVINSKASLTYAEAQMRIDSAAMNDDITTSLRGLNQLAKILKKGRIEKGALTLSSPEIRFHMDSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYDILVKAAKS-KNLQIKTDTAKSLADSLDRAESPDFPYLNTLLRILATRCMMQAVYFCSG--MDNDFHHYGLASPIYTHFTSPIRRYADIIVHRLLAVAIGADCTYPELTDKHKLSDICKNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFE-EKD--------KPKPRLAYDDEIPSLRIEGTVFHVFDKVKVKITLDSSNLQHQKIRMALVEPQIPGINIPPNVADKA----LTAPGGKKRKLEK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2L1-1", "uniprot_id": "RRP44_HUMAN", "id": "Q9Y2L1-1", "name": "Exosome complex exonuclease RRP44", "aln": "----------------MLKSKTFLKKTRAG------GVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVCPQP--------------------------------------HYLLPDTN---------------------VLLHQIDVLEDP-AIRNVIVLQTVLQEVRNRSAPVYKRIRDVTNNQE--KHFYTFTNEHHRETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQ--------VIFITNDRRNKE---KAIEEGIPAFTCEEYVKSLTANPELIDRLACLS---EEGNEIESGKIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLNRAVHEDIVAVELLPKSQWVAPSSVVLHDEGQNEEDVEKEE---------------------ETERMLKT--AVSEKMLKPTGRVVGIIKRNWRPYCGMLSKSDIK----ESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLP------KMPWSITEKDMK-------NREDLRHLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSKASLTYAEAQLRIDSANMNDDITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARS-RNLEIKTDTAKSLAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCSG--MDNDFHHYGLASPIYTHFTSPIRRYADVIVHRLLAVAIGADCTYPELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFE-EKD--------KPNPQLIYDDEIPSLKIEDTVFHVFDKVKVKIMLDSSNLQHQKIRMSLVEPQIPGISIPTDTSNMD----LNGPKKKKMKLGK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q0K2-1", "uniprot_id": "A0A8M9Q0K2_DANRE", "id": "A0A8M9Q0K2-1", "name": "Exosome complex exonuclease RRP44", "aln": "----------------MLKSKTFVKKTRSG------GVLKIVREHYLRDDIWCGSEVCKECK--DEAPVLQEETCIESN-LCPYP--------------------------------------HYVIPDTN---------------------VVLHQIDILEDP-LIRNVIILQTVLQEVRHRSAPVYKRIKDAIHEKE--KHFYTFTNEHHRETFIEREQGESANDRNDRAIRVAAKWYTDHLAKATDGGTLK--------VVLLTNDRANKE---KAEQFGLTVYRCEEYIKSLVGNPELVDRLAMTS---DDQNEITGSKLLFPEHLPLSRIQTGIKNGVFIQGTFHANRDNYLEGTVFVNREGEDINEILLQGLQNLNRAVNQDVVAVELFPKDRWVAPSSVVLQDDNLNDEDTEEDE---------------------NDSKLKSV--ASESSVLKPTGRVVGIIKRNWRPFCGMLAQSQIK----EATRHLFTPADRRIPRIRIETRQAATLIGQRIMVAIDGWPKNSRYPNGHFVKNLGTAGDKETETEVLLLEHDVPHQPFSQAVLSFLP------KMPWGITEEDLK-------VRADLRHLCVCSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQEAANRGTTVYLCGKRIDMVPELLSSNLCSLRSNVERLAFSCIWEMNHKAEIIKTHFTKSVINSKASLTYAEAQMRIDDTTINDDITKSLRGLNKLAKILKAQRIDKGALTLSSPEVRFHIDSETHDPIDLQTKELMETNSMVEEFMLLANISVAQKIYDEFSECALLRKHPAPPPSNYDILIKAAKS-RDLEIHTDSAKALADSLNNATIENFAYFNTLLRILATRCMMQAVYFCSG--MDSDFHHYGLASPIYTHFTSPIRRYADIIVHRLLAVAINADSTYPDLMDKHKQSALCNNINYRHKMAQYAQRASVAFHTQLFFKNKGIINEEGFILFVRKNAIIILIPKFGLEGTVFFE-NKD--------KPSPRLSFDTEGPTLKVEEHTFRIFDRVKVTISLDASNLQHQRIRMALTEPVIPGVSVPIPES---------EPEAKKPKLDR---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC93-1", "uniprot_id": "Q9VC93_DROME", "id": "Q9VC93-1", "name": "Exosome complex exonuclease RRP44", "aln": "----------------MQTLREFTRKTKRG------NILKIVREHYLRDDIGCGSELCRECFQNEVYQLTSQHAN--KSTLFKFP--------------------------------------HYLVLDTN---------------------VVLDQIDVLEED-VLRNVVVLTTVLNEVKHRSSAIYKRFNEIVHDRT--RNFYVFVNEHHKETYADREPDETANDRNDRAIRLATKWYDDHLQASQSSKEFERSGKAATRVVLLTDDAANRA---KAEAEGILVTTAAEYVKSLEDFPLLMDKLSHKT---FDSE--KNGLPQYPPHLSMKELLEGLRQNKLLQGTFQASRENYLEGTVNVEK---FEKGILIQGRESLNRAVDGDLVAVELLPEAEWSAPSEIVLEEKNVYADEVPSEERA-----------------KDENEMLNQVRAAALSAERTPTGRIVGIVRRKWRQYCGILQPSLIE----DTNRHIFVPADRKIPRIRIETRQAAMLQNQRIIVTIDTWPRNSRYPHGHFVRSLGPLGDMATENEVILLEHDVPHCKFSDEVLSFLP------KMPWTITDEDYS-------KRVDLRDLYICSVDPPGCTDIDDALHCKELPNGNLEVGVHIADVSHFIRPGNALDMEAAARGTTVYLVGKRIDMVPELLSSNLCSLVGGVERFAFSCVWEVDNEANVLSKRFHKSVIKSKRAMTYEEAQNIIDDATQQNEIAKSLRNLNRLAKILKKRRMDNGALVLASPEIRFQVDSETHEPLEVEVKQMRETNSMVEEFMLLANITVAEHIATEFSECAVLRRHPRPPPTNFDPLVKSARY-QGFQVDINSGLELSHSLDKCVKADNPYFNTMIRILTTRCMMQAVYFISGSLQKEEFFHYGLAAPIYTHFTSPIRRYSDIMVHRLLAASIGADSTYAQLLDRKSNEELCHNLNYRHKMAQYAGRASVALNTHLFFRGK-EEDEEGYVLFVRKNALQVLIPKYGLEGTLYLKSDKDGKDGVERVKSEIVFTFNEEDHTQRCGDVVFHSFDPVTVRLSLDSSNVQHEKLIFRLVKPYIKGFSVETTTEGTDSQAVSAAPPSKKTKKDKKKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08162-1", "uniprot_id": "RRP44_YEAST", "id": "Q08162-1", "name": "Exosome complex exonuclease DIS3", "aln": "MSVPAIAPRRKRLADGLSVTQKVFVRSRNG------GATKIVREHYLRSDIPCLSRSCTKCPQIVVPDAQNELPKFILSDSPLELSAPIG--------------------------------KHYVVLDTN---------------------VVLQAIDLLENPNCFFDVIVPQIVLDEVRNKSYPVYTRLRTLCRDSDDHKRFIVFHNEFSEHTFVERLPNETINDRNDRAIRKTCQWYSEHLKPYDIN------------VVLVTNDRLNREAATKEVESNIITKSLVQYIELLPNADDIRDSIPQMDSFDKDLERDTFSDFTFPEYYSTARVMGGLKNGVLYQGNIQISEYNFLEGSVSLPR---FSKPVLIVGQKNLNRAFNGDQVIVELLPQSEWKAPSSIVLDSEHFDVNDNPDIEAGDDDDNNESSSNTTVISDKQRRLLAKDAMIAQRSKKIQPTAKVVYIQRRSWRQYVGQLAPSSVDPQSSSTQNVFVILMDKCLPKVRIRTRRAAELLDKRIVISIDSWPTTHKYPLGHFVRDLGTIESAQAETEALLLEHDVEYRPFSKKVLECLPAEGHDWKAPTKLDDPEAVSKDPLLTKRKDLRDKLICSIDPPGCVDIDDALHAKKLPNGNWEVGVHIADVTHFVKPGTALDAEGAARGTSVYLVDKRIDMLPMLLGTDLCSLKPYVDRFAFSVIWELDDSANIVNVNFMKSVIRSREAFSYEQAQLRIDDKTQNDELTMGMRALLKLSVKLKQKRLEAGALNLASPEVKVHMDSETSDPNEVEIKKLLATNSLVEEFMLLANISVARKIYDAFPQTAMLRRHAAPPSTNFEILNEMLNTRKNMSISLESSKALADSLDRCVDPEDPYFNTLVRIMSTRCMMAAQYFYSGAYSYPDFRHYGLAVDIYTHFTSPIRRYCDVVAHRQLAGAIGYEPLSLTHRDKNKMDMICRNINRKHRNAQFAGRASIEYYVGQVMRNN-ESTETGYVIKVFNNGIVVLVPKFGVEGLIRLD--------------------------NLTEDPNSAAFDEVEYKLTFVPTNSDKPRDVYVFDKVEVQVRSVMDPITSKR----------KAELLLK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ::: . : . * * : * . . ::: ... . . **:**. : :*:: *::**:::* .:*.*:. .: :.* .* **. ..*: :: .*. ********* : :** :** *:::*:* *: * .: . :*:: * : * :. : : . :. : . .: *::.. **.:: .. *:**.:* : : ::: * : ****.. * * ***:*. .* ***.:**... :: . * . .. * . **.::* * :*.** : * * * :. .: . :. *: :*::**.**:*: * .:**:::** ** . :** ****:.** . :*.*.:****** : **. **. ** : * : : : * ***. :**:*****.*******.::* *** *********:**::**.*** *.* ***:*** *****:* **.::**** *:*:*** :**::..*:::. .* ****.*: :::* :** **. ::::: .:* * :*: ** *:: *** *:***::.::**** :* ::: *:: ***:**********:**.:* *.: *:**:*. **.:*:: * : . :.:.: ::. *:.**:.. .*:**::**::***** * ** ** :* ***** ************.*::.** ** :*. : *::. :*.*:* :*: **:* ***: . .::.: * .::: * :*.: :*:**:*:** : :. ** * : : .:* :: : : : : .: * : ", "identical_positions": 302, "similar_positions": 294, "identity": "27.09%" }, { "cls_id": "homologset.agr.SGD:S000005382", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZSC2-1", "uniprot_id": "D3ZSC2_RAT", "id": "D3ZSC2-1", "name": "", "aln": "----------------MAAVRKPVLLGFRDSAVKGCPKGPAAWTASKIGGVP------------------------------VYCPLEG-------------------SPFHRLLYVFACA------RRDCSDNQTRSWKVFRSQCLQVPEKETRNGQNQSEGLAAENWCEGSHDWGSDTEETPPPPPPADLGRDSN-DARALDWTDKLQALHLQDSALAVACPSPS-----VPTEVPQFQPYYISVAEEDEYGNVADLDHAHSLLQEYQQREGVDMQQLLSVGC-SDGDEKYEKTKVSSGDPTFYKFMKRISVCQGQILRYSWSGEPLFLSCPTFEVS-EVPVCSG---CGGQRAFEFQLMPALVSMLNSTN-LGLTVEFGTILVYTCKQSCWPPNQQ---MPMEEFCVIQEDPDAFLFK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C5N5-1", "uniprot_id": "PDD2L_MOUSE", "id": "Q8C5N5-1", "name": "uS5 assembly chaperone PDCD2L", "aln": "----------------MAAVRKPVLLGLRDTAVKGCPKGPSAWTSSKLGGVPDALPAVTTPGP---QCGRCA--QPLTLVVQVYCPLDG-------------------SPFHRLLYVFACA------RPGCGNSQTRSWKVFRSQCLQVPEKETWNAQNQSDSLAAENWCEGSQDWGSDTEETPPPP-ASDLGSDSN-DVRALDWTEKLQALRLQDTALAVTCPSPSGEGLTVPTAVPQFQPYYICVAEEEDYGSVVDLDHAHSLLQEYQRREGVDMEQLLSLGS-SDGDEKYEKTTVSSGDPTFYRFMKRIAACQEQILRYSWSGEPLFLSCPTFEVS-EVPACSG---CGGQRTFEFQLMPALVSMLSSAN-LGLAVEFGTILVYTCKQSCWPPNQQ---MPMEEFCVLQEDPDEFLFK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BRP1-1", "uniprot_id": "PDD2L_HUMAN", "id": "Q9BRP1-1", "name": "uS5 assembly chaperone PDCD2L", "aln": "----------------MAAVLKPVLLGLRDAPVHGSPTGPGAWTASKLGGIPDALPTVAAPRP---VCQRCG--QPLALVVQVYCPLEG-------------------SPFHRLLHVFACA------CPGCSTGGARSWKVFRSQCLQVPEREAQDAQKQGNSLAAEDWCEGADDWGSDTEEGPSPQFTLDFGNDAS-SAKDVDWTARLQDLRLQDAVLGAAHPVPP--------GLPLFLPYYICVADEDDYRDFVNLDHAHSLLRDYQQREGIAMDQLLSQSLPNDGDEKYEKTIIKSGDQTFYKFMKRIAACQEQILRYSWSGEPLFLTCPTSEVT-ELPACSQ---CGGQRIFEFQLMPALVSMLKSAN-LGLSVEFGTILVYTCEKSCWPPNHQ---TPMEEFCIIQEDPDELLFK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P46718-1", "uniprot_id": "PDCD2_MOUSE", "id": "P46718-1", "name": "uS5 assembly chaperone PDCD2", "aln": "---------------MAAAAPGPVELGFAEEAP--AWRLRSEQFPSKVGGRPAWLGLAELPGPGALACARCG--RPLAFLLQVYAPLPGR-----------------DDAFHRSLFLFCCR-----EPPCCAGLRVFRNQLPRNNAFYSYEPPSETEALGT-ECVCLQLKSGAHLCRVCGCLAPMTCSRCKQAHYCSKEHQTLDWRLGHKQACTQSDKIDHMVPDHN-----------FLFPEFEIVTET----------EDEILPEVVEMEDYSEVTGSMGGIPEEELDS-MAKHESKE-DHIFQKFKSKIALEPEQILRYGRGIKPIWISGENIPQEKDIPDCP----CGAKRIFEFQVMPQLLNHLKADR-LGRSIDWGVLAVFTCAESCSLGS-----GYTEEFVWKQDVTDTP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47816-1", "uniprot_id": "PDCD2_RAT", "id": "P47816-1", "name": "uS5 assembly chaperone PDCD2", "aln": "---------------MAAVVPVTVELGFVEEAP--AWRLRSEQFPSKVGGRPAWLALAELPGPGALACARCG--RPLAFLLQVYAPLPGR-----------------DEAFHRSLFLFCCR-----EPLCCAGLRVFRNQLPRKNAFYSYEPPSETGASDT-ECVCLQLKSGAHLCRVCGCLAPMTCSRCKQAHYCSKEHQTLDWQLGHKQACTQSDHLDHMVPDHN-----------FLFPEFEIVTET----------EDEIGPEVVEMEDYSEVIGSMEGVPEEELDS-MAKHESKE-DHIFQKFKSKIALEPEQILRYGRGIKPIWISGENIPQEKDIPDCS----CGAKRIFEFQVMPQLLNHLKADR-LGTSVDWGILAVFTCAESCSLGI-----GYTEEFVWKQDVTETP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16342-1", "uniprot_id": "PDCD2_HUMAN", "id": "Q16342-1", "name": "uS5 assembly chaperone PDCD2", "aln": "---------------MAAAGARPVELGFAESAP--AWRLRSEQFPSKVGGRPAWLGAAGLPGPQALACELCG--RPLSFLLQVYAPLPGR-----------------PDAFHRCIFLFCCR-----EQPCCAGLRVFRNQLPRKNDFYSYEPPSENPPPETGESVCLQLKSGAHLCRVCGCLGPKTCSRCHKAYYCSKEHQTLDWRLGHKQACAQPDHLDHIIPDHN-----------FLFPEFEIVIET----------EDEIMPEVVEKEDYSEIIGSMGEALEEELDS-MAKHESRE-DKIFQKFKTQIALEPEQILRYGRGIAPIWISGENIPQEKDIPDCP----CGAKRILEFQVMPQLLNYLKADR-LGKSIDWGILAVFTCAESCSLGT-----GYTEEFVWKQDVTDTP---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1A3-1", "uniprot_id": "Q9W1A3_DROME", "id": "Q9W1A3-1", "name": "", "aln": "---------------------MEIDLGFAEKSDNGAW-LSNRYFPSKLGGQPAWLELEALPPTSQLQCSKCR--APKSFLAQLYAPFED------------------EYNFHRSIYVFLCRNSDCQEAQNASNFTVLRSQLPRKNKFFSEEEPSDVGQPLP-AVPCLK-----KLCAACGCHAPHACSKCKAIHYCSPEHQRAHWPQ-HKPNCGAP-EVATEKPLTQ-----------IVFPEFEIVMDSNPVESGEEDKDDEARLAEFQELESSGKTGDLSNVSEAEMDKYFGNSAAAD-DKTFRQFKKQTAAEPDQIVRYKRGGQPLWITNTVKTVEDQLNKLPNCIACGGERQFEFQIMPQALTLLEDE-----NLDWGVLAVYTCAKSCPID------GYVEELLIKQDIVAEDQS-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25040-1", "uniprot_id": "TSR4_YEAST", "id": "P25040-1", "name": "uS5 assembly chaperone", "aln": "MSKIEELPPSDTDDHSYSSKPGDVFLAFVDAPVKETDDILVE--DSFIGGEPKWLHPDSEPPAELLKCGACKSADNMKLLLQAFSPLDDEQMSAIQQRLGINNMSYINPQDDRVLYVFLCT----ECQRKGNSVRCIRGVKKNKNVDSLSEKMASTSLEKDFQINPFDLSNNSDSKCNAFSSNPFGGANANPFGADSINSNISQSKDEGKKKESATVSAKTARKLHDLQKDKEYDGNKCFKSCLLYVEEETFKNKKPAHLQLPKNLKIDKEALDLTGDEDLEKDP-IKLDPRTEKLSKFLDDDTFQKFQEVVGYNPLQVLRYDLGGKPLLYAETKVDILSTVPRPGYN--PSSQRIFEMQLMPKMIFDLEEVVSVDNGMEWGTILVFTDVENYMPEFDEHGVGYVEECVKVQWESRT----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.: : . * :** * :.*: . .* :.:* * ..: * : . . * . . . . . : . . * : . : : . * : * * :* . *::** . *: : : ..:* :*:*:** : *. :::* : *:* :. ** * ", "identical_positions": 32, "similar_positions": 57, "identity": "7.6%" }, { "cls_id": "homologset.agr.SGD:S000005383", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABZ3NN93-1", "uniprot_id": "A0ABZ3NN93_RAT", "id": "A0ABZ3NN93-1", "name": "Translation initiation factor IF-2, mitochondrial", "aln": "MRNMNQKLLKLEKLLRFHTICRQLHSLSQRRLLAWWKHGSAPASPVWADWLCARPWPTDVLTGSALHQHRLLVTKKEKRPPRSQLSPIKTK----KEVEVWVGMTVEELARAMAKDTDCVYEALLNTAIDIDSLEANSHLDEVWIKEVIKKAGMKLKWSKLKLER---IRENKDAVRRPGADPALLKPRSPVVTIMGHVDHGKTTLLDKLRETQVAAMEVGGITQHIGAFLVSLP-SGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAGVPIILAINKCDKT------DADPEKVKKELLAYDVVCEEYGGDVQAVHVSALTGKNLMALAEATIALAEMLELKAD--PTGPVEGTVIESFTDKGRGPVTTAIIQRGTLKKGSILVAGKSWAKVRLMFDENGKTVNEAYPSMPVGIIGWRDLPSAGDEILEVQSEPRAREVVDWRKSEQKEEKGKDDLKIMEEKRKEHQEAHRKAREKYGSLHWKQRSYIKYLERKEQRPLKPKEKVERDSNVLPIIIKGDVDGSVEAILNLLDTYDASHECELELVHFGLGDISENDVTFAETFDGVIYGFNVDAGSAIQQSAAQKGVKIKLHKIIYHLIEDLQEELSNRLPYKVEEYPIGEASILATFTITEGKKKVPVAGCRVQKGQLERQKKFKLIR--NGQVIWKGSLTSLKHHKDDVLVIKTGVDCGLSLDEENVEFKVGDQVICYEENKVPTKTSWDPGF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YJ5-1", "uniprot_id": "IF2M_MOUSE", "id": "Q91YJ5-1", "name": "Translation initiation factor IF-2, mitochondrial", "aln": "---MNQKLLKLENLLRFHTICRQVHSPSQRRLLAWCRHGFAPASSVWRDLLGARSWQTDMLIGSALHQHRLLVTKKEKRPPRSQLSPVKTK----KEVEVWVGMTVEDLASAMAKDIDCVYEALLNTAIDVDSLEANSHLDEVWIKEVIKKAGMKLKWSKLKQER---IRENKDAVRRPGTDPALLKPRSPVVTVMGHVDHGKTTLLDKLRETQVAAMEVGGITQHIGAFLVSLP-SGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAEVPIILAINKCDKT------DADPEKVKKELLAYDVVCEEYGGDVQAVHVSALTGDNLMALAEATIALAEILELKAD--PTGPVEGTVIESFTDKGRGPVTTAIIQRGTLRKGSILVAGKSWAKVRLIFDENGKILNEAYPSMPVGIIGWRDLPSAGDEILEVESEPRAREVIEWRKSEQKEEKGKDDLKIMEEKRREHQEAHRKAREKYGSLHWKERSYIKFLERKQQRPLKPKEKVERQSNVLPIIIKGDVDGSVEAILNLLDTYDASHECELELVHFGLGDISENDVTFAETFDGVIYGFNVEAGSAIQQSAAQKGVKIKLHKIIYHLIEDLQEELSSRLPHTLEEYPIGEASILATFTVTEGKKKIPVAGCRVQKGQLERHKKFKLIR--NGQVIWKGSLTSLKHHKDDISVIKTGMDCGLSLDEEKVEFKPGDQVICYEENKVPTKTSWDPGF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46199-1", "uniprot_id": "IF2M_HUMAN", "id": "P46199-1", "name": "Translation initiation factor IF-2, mitochondrial", "aln": "---MNQKLLKLENLLRFHTIYRQLHSLCQRRALRQWRHGFSSAYPVWTAQLCAWPWPTDVLTGAALSQYRLLVTKKEEGPWKSQLSSTKSK----KVVEVWIGMTIEELARAMEKNTDYVYEALLNTDIDIDSLEADSHLDEVWIKEVITKAGMKLKWSKLKQDK---VRKNKDAVRRPQADPALLTPRSPVVTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLP-SGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIILAVNKCDKA------EADPEKVKKELLAYDVVCEDYGGDVQAVPVSALTGDNLMALAEATVALAEMLELKAD--PNGPVEGTVIESFTDKGRGLVTTAIIQRGTLRKGSVLVAGKCWAKVRLMFDENGKTIDEAYPSMPVGITGWRDLPSAGEEILEVESEPRAREVVDWRKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREKYGHLLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDASHECELELVHFGVGDVSANDVNLAETFDGVIYGFNVNAGNVIQQSAAKKGVKIKLHKIIYRLVEDLQEELSSRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKFKLTR--NGHVIWKGSLTSLKHHKDDISIVKTGMDCGLSLDEDNMEFQVGDRIVCYEEKQIQAKTSWDPGF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VAV2-1", "uniprot_id": "Q9VAV2_DROME", "id": "Q9VAV2-1", "name": "", "aln": "-------------MLRIINISRLGNTLHFSRAVTQWQLPLA--------------FQREFHVSAARLKRRKTAEEK-KSPRIIEYSPKKFQTAGGGASDIWRHMTVAQLAKELERSLDDVQEAMLYVKGADNIEPAFKLADLKIIQEIAKKLGAKTRVVATPEETNADEQKERDVAPRPPAAPELLQPRPPVVTVMGHVDHGKTTLLDSLRGADVAAGEAGGITQHIGAFTVTLE-NGERVTFLDTPGHAAFSAMRARGAVATDIIVLVVAAEDGVMAQTREVIQLAKEAQVPIIVALNKIDKP------EANIEKSKRELAQMGLALEEHGGDVQVIPISALKGTNLELLAEAVSTQATLMGLKAD--PTGLVEGIVVESKTDPRRGKLSTAIVSRGTLRKGSVLLSGLAHAKVRGLFDHNGQPLSEAPPGTPVEILGWRELPLAGDLILEVETEKKAHAVLKYREHESQQEKIESSSDEIRKKEEEHQAKYRAEREAR-------RLAGRFRMRGGQRVKQVDENEGKPR--VSVIIKGDVHGSVEAILDVLETYNSNESCRLDIVHYGVGNVTEGDLELAKAFHAIIYAFAVET----PQLKAAKEVNIRSYNIIYRLIDDLKEQLSSKLPPVEVEEVLGEANVLQNFLINEGRKEVPVAGCRCTKGVLKKAQKFRLLR--DGEVVYDGPLESMRHLKNEVDTIKKDVECGLRFRDTKVLPQAGDILQCYTTKMEAQQTDWDPGF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25038-1", "uniprot_id": "IF2M_YEAST", "id": "P25038-1", "name": "Translation initiation factor IF-2, mitochondrial", "aln": "-------------MLRRHGLFWLKTCPRLNVLLNQS-----------------IPIPHLLHSRDICQQRWYAKGKRRNQISKKELKPLNFS--------IPNYISVNKLANLLNCRVERLIKDLT--ALGFENITTTYILSKEYVELILQEYNFALPNLSTSTNL-----DNVYDELKSPVNPKLLTKRAPVVTIMGHVDHGKTTIIDYLRKSSVVAQEHGGITQHIGAFQITAPKSGKKITFLDTPGHAAFLKMRERGANITDIIVLVVSVEDSLMPQTLEAIKHAKNSGNEMIIAITKIDRIPQPKEREKKIEKVINDLIVQGIPVEKIGGDVQVIPISAKTGENMDLLEESIVLLSEVMDIRAENSPKTIAEGWIIESQVKKQVGNVATVLVKKGTLQKGKILICGNTFCKIKNLIDDKGIPILKATPSYATEVLGWKDVPHVGDEVIQVKSEAIAKKFISKRQDLIEVQKNSSIVEKLNEERALAKEQHLNK-------------------ELEHENTVQEHEQNTGPKLINYIIKCDVSGSAEAVSESISSLG-NDEVRCNVISSSVGIPTESDLKMAQITESTILCFNLGN-LPSEVINNRAGIKIKQYNVIYKLIEDVTETLTENLKPIFEKKIVSTVDVRETFDFRLKKKIIRIAGCKVNNGVIKKNSLVQVVRGPNEDVIFDGKISTLKHNKDDVAEVSKGHECGITFESGFEGFKPGDKILVYENVRVPRYL------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** : : . : :: : : .. : . : ::: .** : : : : : : : . :: : : . : .: :. . * ** *.****:**********::* :* :.*.* * ********** :: .*:::*********** ** *** ***:****:.:*.:* ** * *: **:: :*:*:.* *: : . ** .:* .: *. *****.: :** .* *: * *: : :: ::*: *. .** ::** .. * ::*.::.:***:**.:*:.* .*:: ::*.:* : :* *. .. : **:::* .*: :::*::* *: .:. *: : :* .. . :.::. : : . : ..: : *** ** **.**: : :.: . ... . ::: .:* : .*: :*: .. * * : ::*: :::**:*::*: * *:..* : :. ..: .* . :* : :***: :* ::: . .:: * : .*::.* : :::* *::: :... :**: : . : ** : * ", "identical_positions": 155, "similar_positions": 227, "identity": "20.72%" }, { "cls_id": "homologset.agr.SGD:S000005387", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIN6-1", "uniprot_id": "LETM1_RAT", "id": "Q5XIN6-1", "name": "Mitochondrial proton/calcium exchanger protein", "aln": "MASILLRSCRGRGPARLASP-RAASPRGSLRDRACLSCTRTVGLTSHESVLSRCCTP-ANPVYLYFKSEPLS---------------CWTQRPECQGTVAR---AAWTPASARLV--------VTGPQYLPVRGWHSSSPLGEDSMIEKSLKSLKDKNKKLEEGGPVYSPPAQVV-VKKSLGQKILDELKHYYHGFRLLWIDTKIAARMLWRILNGHTLTRRERRQFLRICADLFRLVPFLVFVVVPFMEFLLPVVVKLFPNMLPSTFETQSIKEERLKKELRVKLELAKFLQDTIEEMALK--NKAAKGNATKDFSAFFQKIRETGERPSN----EEIMRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLTMRLRSIKADDKLISEEGVDSLTVKELQAACRARGMRALGVTEDRLKGQLKQWLDLHLYHEIPTSLLILSRAMYLPDTLSPADQLKSTLQTLPEIVAKEAQVKAAEVEGEQVDNKAKLEATLQEEAAIQQEHLE-ELKRAA----------------ETAKDIQPEVAEATVPGRPGAELQPKMVDVIPPSEILKDTAPVLEGLKGEEITKEEIDILSDACSKLKEQKKS------LTKEKEELELLKEDVQDYSEDLQEIKKELSKTGDEKYIEESTASKRLSKRVQ--------------------------------------------------QMIGQIDGLITQLETTQQ--NGKLDPAAASSPTGESVISVDELISAMKQIKHIPEHK----LISLTSALDENKDGNINIDDLVKVIDLVNKEDVQISTTQVAEIVATLEKEEKVEEKEKAKEKAEKE-AAEVKN----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2I0-1", "uniprot_id": "LETM1_MOUSE", "id": "Q9Z2I0-1", "name": "Mitochondrial proton/calcium exchanger protein", "aln": "MASILLRSCRGRGPARLAPP-RAASPRGSLRDRACLSCTRTLGLTSRESVLSRCCTP-AHPVYLCFKGEPLS---------------CWTQRPECQGTAAR---TTWTPASARLV--------VTGPQYLPVRGWHSSSPLGEDSVIEKSLKSLKDKNKKLEEGGPVYSPPAQVV-VRKSLGQKVLDELRHYYHGFRLLWIDTKIAARMLWRILNGHTLTRRERRQFLRICADLFRLVPFLVFVVVPFMEFLLPVVVKLFPNMLPSTFETQSIKEERLKKELRVKLELAKFLQDTIEEMALK--NKAAKGNATKDFSAFFQKIRETGERPSN----EEIMRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLTMRLRSIKADDKLISEEGVDSLTVKELQAACRARGMRALGVTEDRLKGQLKQWLDLHLHHEIPTSLLILSRAMYLPDTLSPADQLKSTLQTLPEIVAKEAQVKVAEVEGEKVDNKAKLEATLQEEAAIQQEHLE-ELKRAS----------------EAVKDIQPEVAEATLPGRPGPEPQPPVDDVILPSEVLTDTAPVLEGLKGEEITKEEIDILSDACSKLQEQKKS------LTKEKEELELLKEDVQDYSEDLQEIKKELSKTGEEKYIEESAASKRLSKRVQ--------------------------------------------------QMIGQIDGLITQLETTQQ--DGKLGPSQS-TPTGESVISITELISAMKQIKHIPEHK----LISLTSALDDNKDGNINIDDLVKVIDLVNKEDVQISTTQVAEIVATLEKEEKIEEKEKAKEKAEKE-AAEVKN----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95202-1", "uniprot_id": "LETM1_HUMAN", "id": "O95202-1", "name": "Mitochondrial proton/calcium exchanger protein", "aln": "MASILLRSCRGRAPARLPPPPRYTVPRGSPGDPAHLSCASTLGLRNCLNVPFGCCTP-IHPVYTSSRGDHLG---------------CWALRPECLRIVSR---APWTSTSVGFV--------AVGPQCLPVRGWHSSRPVRDDSVVEKSLKSLKDKNKKLEEGGPVYSPPAEVV-VKKSLGQRVLDELKHYYHGFRLLWIDTKIAARMLWRILNGHSLTRRERRQFLRICADLFRLVPFLVFVVVPFMEFLLPVAVKLFPNMLPSTFETQSLKEERLKKELRVKLELAKFLQDTIEEMALK--NKAAKGSATKDFSVFFQKIRETGERPSN----EEIMRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLTMRLRSIKADDKLIAEEGVDSLNVKELQAACRARGMRALGVTEDRLRGQLKQWLDLHLHQEIPTSLLILSRAMYLPDTLSPADQLKSTLQTLPEIVAKEAQVKVAEVEGEQVDNKAKLEATLQEEAAIQQEHREKELQKRS----------------EVAKDFEPERVVA-APQRPGTEPQPEMPDTVLQSETLKDTAPVLEGLKEEEITKEEIDILSDACSKLQEQKKS------LTKEKEELELLKEDVQDYSEDLQEIKKELSKTGEEKYVEESKASKRLTKRVQ--------------------------------------------------QMIGQIDGLISQLEMDQQ--AGKLAPANG-MPTGENVISVAELINAMKQVKHIPESK----LTSLAAALDENKDGKVNIDDLVKVIELVDKEDVHISTSQVAEIVATLEKEEKVEEKEKAKEKAEKE-VAEVKS----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LY46-1", "uniprot_id": "LETM1_DANRE", "id": "Q1LY46-1", "name": "Mitochondrial proton/calcium exchanger protein", "aln": "MASILLTRSR-TPLLKTSRSLKNEFRKGKLSEGACFNCTALRLATNSPGVLGGIVWPHASSVQYLDNSSVLQRR------------LSRSPRLYCAILVPDPALPVHSRSTYHRT--------LAWPQNAPVRWVHTTGRLLDDSKVERSLRTLKDRNKKLEEGGPVYSPTVDAEPVRRTIRQRVIDEVKHYYHGFRLLWIDTTIAVRMLWRVLNGHILSRRERRQFLRTCADVFRLLPFLVFIIVPFMEFLLPVALKLFPNMLPSTFETQSKKEERLKKELRVKLEMAKFLQDTIEEIALR--NKASKGNVTEEFSTFFQKIRDSGEIPSN----EQIIRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLIMKLRAIRADDKLIAEEGVDSLTANELQAACRVRGMRALGVTEERLREQLKQWLELHLNQHIPTSLLLLSRAMFLPDTLSPADQLKTTLQNLPEIMAKEAQVKVAELDFSKVDNKTKLETTLQEEAAIRQENRERELERLAD---------AAEKAKEQTQSQEAEVLEVEGERRVDAEHALSSVDVAIHSETLRDTAPVLEGIKGEEITKEEIDMLSDACTKLKEQKNL------LTKEKEELEDLKDDVQEYSEDLEEIKRELSKTGQEKAVEESKASQRLSKRVN--------------------------------------------------RMIGRMDKIITELEKDKMVLDGQMDSETT-PPIGENLISINELITVMKQIQNIPEHK----LLSIADALDENKDGKIDIDDVIKVVELIDKEDIDISTNQVAEIMVMLQKEEKLMEKEKAKEKVEKEQAAKIQN----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7TNU7-1", "uniprot_id": "LETM2_MOUSE", "id": "Q7TNU7-1", "name": "LETM1 domain-containing protein LETM2, mitochondrial", "aln": "MAFYSYNSFLAIFWTRLPGH----------------------------SVYPSCSHF-PSLAFLHLPDSHLR-------------------TAYIKNCGSR---KYSYPSLTGNN--------KVHPLRTRLPQKLHT-TCWLQHVPGKPQLEQTGK-PKAASPQPTKEAKTETTEEKRSLRQKIVNELKYYYKGFSLLWIDTKVAARIVWRLLHGNALTRRERRRLLRTCADVFRLVPFMVFIIVPFMEFLIPVFLKLFPDMLPSTFESESKKEEKQKKTMAAKLEIAKFLQETMTEMARR--NRAKLGDASSQLSSYVKQVQ-TGHKPST----KEIVRFSKLFKDQLALEHLDRPQLVALCKLLELQTFGTNNLLRFQLLMTLKSIKADDEIIAKEGVKALSVSELQSACRARGMRSLGLTEEQLCQQLTGWLDLHLKENVPPSLLLLSRTFYLIDVKP----------------------KPIELPPNIETPKPNLGIPTPPPPESK--------------------------------------------------------------ENLTDSAPQLKGTKDEEFIQ------------LPPVPSS------LIAPAATIS---------KEAILQAKSQETS-------QNSKADSKGA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2VYF4-1", "uniprot_id": "LETM2_HUMAN", "id": "Q2VYF4-1", "name": "LETM1 domain-containing protein LETM2, mitochondrial", "aln": "MAFYSYNSVLAIARTRFPSH----------------------------FVHPTCSSYSPSCAFLHLPDSHLN-------------------KTCMKNYESK---KYSDPSQPGNT--------VLHPG-TRLIQKLHTSTCWLQEVPGKPQLEQATKHPQVTSPQATKETGMEIKEGKQSYRQKIMDELKYYYNGFYLLWIDAKVAARMVWRLLHGQVLTRRERRRLLRTCVDFFRLVPFMVFLIVPFMEFLLPVFLKLFPEMLPSTFESESKKEEKQKKKMAVKLELAKFLQETMTEMARR--NRAKMGDASTQLSSYVKQVQ-TGHKPST----KEIVRFSKLFEDQLALEHLDRPQLVALCKLLELQTFGTNNLLRFQLLMKLKSIKADDEIIAKEGVTALSVSELQAACRARGMRSLGLTEEQLRQQLTEWQDLHLKENVPPSLLLLSRTFYLIDVKP----------------------KPIEIPLSGEAPKTDILVELPTFTESK--------------------------------------------------------------ENMVDLAPQLKGTKDEDFIQ------------PPPVTSS------PITPSTPISLPKGPITSSEEPTLQAKSQMTA-------QNSKASSKGA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P91927-1", "uniprot_id": "LETM1_DROME", "id": "P91927-1", "name": "Mitochondrial proton/calcium exchanger protein", "aln": "MNALLRHKGRNLRTSHLAQNVYKRFLKSNCCACSSVNVTDEPAKEDELPRRSASTSVLELSRSLGTYRRFQPHANYGYDYSGYGFRHLHTSRTLLETSSSKIDATVKKLKNQQKEKVEEIMKEVANGQAAAVRASSAATATASSEKGQNASATAGSTSATASTTSLAKTADKSVAKPKKPLRTRIWDELVHYYHGFRLLFIDVAICSKLLWRVLNGKTLTRRENKQLQRTTSDLFRLIPFSVFIIVPFMELLLPLFIKFFPGMLPSTFQTSTDRQEKLRQSLSVRLEVAKFLQQTLDQMPVQ--HKEHSSEEAKQFEAFFTKIRNPTEPVSN----DEIIKFAKRFDDEITLDSLSREQLAALCRVLELNTIGTTTLLRFQLRLKLRSLATDDRVIAREGVDSLDLLELQQACKARGMRAYGLTEERLRFQLKEWIDLSLNEQVPPTLLLLSRTMLISDDSITTDKLKETIRVLPDAVGAHTRHAIGESEG-KVDNKTKIEIIKEEERKIREEREEEREETIAKRSAIKEEIPAPYVFAEKLSGSQDLLDHKEQSSVSETDKGISSTDVQLLSEALKTLSSDKQLVVEKETIKELKEELADYKEDVEELREVRQVVKEPVRESRAAKLLYNRVNKMISQLDNVLNDLEARQHQIKQAESSDYAASSPTVEPQQMVHIDELVATIRRMKEASDEERFKVVGDLLVKLDADKDGVISVNEITKAVQSIDREATNIDKKQLEEFTELLSKLASRRRHEEIVHIDDLMNNIKVLKETSDEARLKHIEAVLEKFDADKDGVVTVNDIRKVLESIGRDNIKLSDKAIEELISLLDKEQVLQAEQKIEKAIAKSMKEAEKLKSEVDKADKDLSKLVNDIHDSAKEIQDIANEMRDKEETVPDKAKELKAEPAFKDTAKTLKDNAKDLDDLAKDPKSDPKSPTKASTGSGPAGLSGGGPSSGSSGIATGSTTESALREAAERQMEKILPSTDIGLPPTIQTPSQPPTSKKATATASTLSTTITAKKLL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08179-1", "uniprot_id": "MDM38_YEAST", "id": "Q08179-1", "name": "Mitochondrial distribution and morphology protein 38", "aln": "---MLNFASRASCVTRRQAS-----------------------------------------------------------------------LYFVKNQGPR-----------------------LIASTIPSCHWPLRAQGVQPNYPLSLRFYSTDKSKSVTKPVAPTSTDAPAK-PKETLMVKVKHALKHYANGTKLLGYEIKVSTKLLIKFAQGYELSRRERNQLRRTMGDVFRLIPFSAFLIIPFAELFLPFALKLFPNLLPSTYESGKDKQAKRNKLIEIRKKTSEFLHETLEESNLITYNTIENAEKKQKFLNFFRKLYSAKEGKIMTFQHDEISAIAQMFKNDSVLDNLSRPQLAAMSKFMSLRPFGNDNMLRYQIRSKLKDIMNDDKTIDYEGVESLSQEELYQACVSRGMKAYGVSKEDLVDNLKVWLELRLRQKIPSVLMVLSSTFTFGGLPK------------------ENYSKAFSPLAEKKETKSKYDDLLDLYYDGILQVLSSIPDPVYN-------------------------------------------------VAKLDVSESKSSAAETEAEKQVAEKKIKTEEKPEETAIP-------KEEATAKESVIATTASAVTPKLVVVNEKAETAKTEEISQEKENAEPTDSAE----------------------------------------------------------------------------------------------------------------ATEAEEKKTSDDNEFKLNVLKEQEELIKKEEEEAKQRASREHVPDDINLDEEEEAKSVPPIPADQAAKTFVIKKD-------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . :.. :: . : :* :* ** : :. ::: :. :* *:***..:: * *.***:** .*:::** *:::*. :*:** :****::: . :: : .: : : : ::**::*: : : .. .: :. :: . . .:* ::: *.:: .*: * * **.*:.:.:.*..:*. .:**:*: *: : **. * *** :* ** ** ***:: *:::: * :*. * :* * ..:*. *::** :: : . . *.. : . : : . : :. : ", "identical_positions": 70, "similar_positions": 128, "identity": "6.86%" }, { "cls_id": "homologset.agr.SGD:S000005391", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P6S4-1", "uniprot_id": "SIL1_RAT", "id": "Q6P6S4-1", "name": "Nucleotide exchange factor SIL1", "aln": "-MAPQHLPSTRMAPQGMLLGLLLASCLTFCLSCQNSNNFALTNPEKSTHEDSDTKETRREEELDAEVLEVLNPTQEWQALQPGQAVPAGSHVRMNLQTGVNEVKLQQEDKFQSNWKGFKRGRRLDINTNTYTSQDLKSALAKFKEGTEMENSKDELARQATVKQLFRPIEELKKEFDELNVVLETDMQIMVRLINKFNSSS-----SSLEEKVAALFDLEYYVHQMDNAQDLLSFGGLQVVIN--GLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLP-----AKKKVLFALCSLLRHFPYAQQQFLKLGGLQVLRSLVQEKSAKV-LAVRVVTLLYDLVTEK-MFAEEEAELTQESS-PEKLQQYRQVQLLPGLREQGWCEITAQLLA------LPEHDAREKVLQTLGALLATCRDRYRQDLELSRTLGSLQAEYQALASLELQEGEDDGYFRELLASIDSLVKELR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPK6-1", "uniprot_id": "SIL1_MOUSE", "id": "Q9EPK6-1", "name": "Nucleotide exchange factor SIL1", "aln": "-MAPQHLPSTRMASPGMLLGLLLTSCLTLCLSCQNSNNFALTNPEKSIHQESDTKETREEEELDTEILEVFHPTQEWQTLQPGQAVPAGSHVRMNLQTGVNEVKLQQEDKFQNNLKGFKRGRRLDINANTYTSQDLKSALAKFKEGTEMENSKDELARQATVKQLFRPIEELKKEFDELNVVLETDMQIMVRLINKFNSSS-----SSLEEKVAALFDLEYYVHQMDNAQDLLSFGGLQVVIN--GLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATNQPLP-----AKKKVLFALCSLLRHFPYAQQQFLKLGGLQVLRSLVQEKSAKV-LAVRVVTLLYDLVTEK-MFAEEEAELTQDSS-PEKLQQYRQVQLLPGLQEQGWCEITAQLLA------LPEHDAREKVLQTLGALLTTCRDRYRQDLQLSRTLGRLQAEYQALASLELQEGEDDGYFRELLASINSLMKELR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H173-1", "uniprot_id": "SIL1_HUMAN", "id": "Q9H173-1", "name": "Nucleotide exchange factor SIL1", "aln": "-MAPQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYEDKFRNNLK----GKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSS-----SSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVIN--GLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLT-----AKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRTLVQEKGTEV-LAVRVVTLLYDLVTEK-MFAEEEAELTQEMS-PEKLQQYRQVHLLPGLWEQGWCEITAHLLA------LPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGRTLASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B777-1", "uniprot_id": "A0ACD6B777_DANRE", "id": "A0ACD6B777-1", "name": "Nucleotide exchange factor SIL1", "aln": "MLTSRVMANKWRVRFGLTVTFWLLS-LHLIFAHDVKSPTALLIKEDS--DDLNNAEETHLEDEDPEDLEVFRPTDKWQTLRPGQAVPAGSHVRLNLQTGQREVKMGEEEGFK-YWKDGNRQGMMNMDSHSFTAEELKKALKKFKKGADDPVDQQE---EDAVRAKFRPMDELKKDMEALDMLVETDIQVMRRLLDQFNNTN-----STTEEKVAALLDLEYLVHQVDNAQNLVSMGGMSLVIR--YLNSTDVRLQECAAFVLGSAVSSNPSVQVEAVEGGALQKLLTLLATQRPMT-----VKKKVLFAVASLLRHFPFAQSHFLKLGGVQVLSELFQTPGAEA-MRVRIITVLYDMIIEKELISQVGLDIIPDSSHQERLRQYAEVSLLPVLVEQGWCRLVPELLE------SPEHDWREKALRTLLAMMAQCQTQFKQNAGLTASLSELQKQYQELVLTEQDVGEEDGYFGEILTLVDSMVVKMRQV-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBV5-1", "uniprot_id": "SIL1_DROME", "id": "Q9VBV5-1", "name": "Nucleotide exchange factor Sil1", "aln": "--------MSGKQVVILLGSVLILGCLQVAAATETDN-----------------------------KTNDFVATDEWQTIAEGQAIPRGLHVRINLQTGLKEAKLLDE---------SERGTSLQSQPDDQNARESHDDNEPLALDYKPDIIEES---IRRVKEQKKSYAELRKAYKEFQKNFRTDGELIVQLIDQFRNFSRTPLESEMRSKLDCLENLEYLLHQIDNALMFIDNGGLDDVLLPIVVNDTSTSLRVSAMRVLGSLASNNPKAQIKVFEKNFGSHLAQILTSSGNVG-----EISAALHAFGALLRKFPLAQQRVLSTSGTQALIKVLQSPDVELRSKAKVVTLISDLVLEKRSVLDVSKDDPEASS---TMAQYVLLDFESWLKTPGYCAAVDTVLTKEFLLLLEQPEVVEQFATALETTEDMCTSTWSQSSGLRHALLTVRNRYAN--STDEYRLEVSQILAKLCERLFNKPKHTEL--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08199-1", "uniprot_id": "SIL1_YEAST", "id": "Q08199-1", "name": "Nucleotide exchange factor SIL1", "aln": "MVRILPIILSALSSKLVASTILHSSIHSVPSGGEIISAEDLKELEIS---------GNSICVDNRCYPKIFEPRHDWQPILPGQELPGGLDIRINMDTGLKEAKLNDE-----------------KNVGDNGSHELIVSSEDMKASPGD--------------------YEFSSDFKEMRNIIDSNPTLSSQDIARLEDSF--------DRIMEFAHDYKHGYKIITHEFALLANLSLNENLP--------LTLRELSTRVITSCLRNNP-PVVEFINESFPNFKSKIMAALSNLNDSNHRSSNILIKRYLSILNELPVTSEDLPIYS-TVVLQNVYERNNKDKQLQIKVLELISKILKADMYENDDTNLILFKRN--AENWSSNLQEWANEFQEMVQNKSIDELHTR---TFFDTLYNLKKIFKSDITINKGFLNWLAQQCKARQSNLDNGLQERDTEQDSFDKKLIDSRHLIFGNPMAHRIKNFRDEL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . . . : . : : . ..**.: ** :* * .:*:*::** .*.*: * : :.: : . *: . . : . :: : : : ::.. : : :: : : : :: .:. : :: : *: : .** :: .: . . :::: : . : ::*..:* :. . . .* : : . . ::: :: .:: . : . . : : :: : . *. : . . . : : . . ", "identical_positions": 21, "similar_positions": 117, "identity": "4.29%" }, { "cls_id": "homologset.agr.SGD:S000005392", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M808-1", "uniprot_id": "HIKES_RAT", "id": "Q5M808-1", "name": "Protein Hikeshi", "aln": "--MFGCLVAGRLVQTAAQQVAED----KFVFDLPDYENINHVVVFMLGTIPFPEGMGGSVYFSYPDSNGVPVWQLLGFVTNGKPSAIFKISGLK--------------------SGEGSQHPFGAMN--IVRTPSVAQIGISVELLDS---LAQQTPVGSAAVSSVDSFTQFTQKMLDNFYNFASSFALSQAQMTP-------------------NPSEMFIPANVVLKWYENFQRRLAQNPLFWKT----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DD02-1", "uniprot_id": "HIKES_MOUSE", "id": "Q9DD02-1", "name": "Protein Hikeshi", "aln": "--MFGCLVAGRLVQTAAQQVAED----KFVFDLPDYENINHVVVFMLGTIPFPEGMGGSVYFSYPDSNGVPVWQLLGFVTNGKPSAIFKISGLK--------------------SGEGSQHPFGAMN--IVRTPSVAQIGISVELLDS---LAQQTPVGSAAVSSVDSFTQFTQKMLDNFYNFASSFALSQAQMTP-------------------NPSEMFIPANVVLKWYENFQRRLAQNPLFWKT----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53FT3-1", "uniprot_id": "HIKES_HUMAN", "id": "Q53FT3-1", "name": "Protein Hikeshi", "aln": "--MFGCLVAGRLVQTAAQQVAED----KFVFDLPDYESINHVVVFMLGTIPFPEGMGGSVYFSYPDSNGMPVWQLLGFVTNGKPSAIFKISGLK--------------------SGEGSQHPFGAMN--IVRTPSVAQIGISVELLDS---MAQQTPVGNAAVSSVDSFTQFTQKMLDNFYNFASSFAVSQAQMTP-------------------SPSEMFIPANVVLKWYENFQRRLAQNPLFWKT----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q568T4-1", "uniprot_id": "HIKES_DANRE", "id": "Q568T4-1", "name": "Protein Hikeshi", "aln": "--MFGCLVAGRLVQTDAQQVASD----KFVFNLPDYEHVNHVVVFLLGTVPFPEGLGGAVYLCVPGGAAGQVWQLLGFITNEKPSAIFRISGLK--------------------AGEGSSHPFGMMD--APAAPSMAQVGVSVEGLHL---LAQQTPVSSSAVSTLDSFTQFTQKMLDSLFNFTSSFALSQSQMSP-------------------NPSEMFIPASSIRRWYENFQRRLMQNPNFWKT----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0C7-1", "uniprot_id": "OPI10_DROME", "id": "Q9W0C7-1", "name": "Protein OPI10 homolog", "aln": "MSLFGLIVSGRLPQSDFVAVDAT----KLLVNVPDIESVNYLVVFLTGVSPLPVGTSAAIYFSWPDANAAPTWQYLGHINNTKPSAIFKIAQLKK-------------------SHELEAQAHGMVFG-SQEISHIAQIGVSLEPELT---VAQQTP----AVSTANDNKQFGQRMLENFFNYASSFGVAARDIPP-------------------ISSETFVPFSVVQNWYTNFQRRMEQNPNFWKY----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08202-1", "uniprot_id": "OPI10_YEAST", "id": "Q08202-1", "name": "Protein OPI10", "aln": "--MFAAIASGNPLQLSVEVPNSNGLQHTIVLSRTKPKLYSHITLFILPNVTFPQDYIATVYFKLSPQE---EFKLFGYLSSEKPSAIFKVQIPSSKKDAGDTSDGLGEIDMDVDDGSGAADPFTDTNGSSSNNISELIIGISIEPREQGMMKLEEWKASMNAEAQKNNSLILSRPNLGIIRNITTAGQLAQVYPSLTQELAAKIVQHAYNYLSGFLDAQGNVPIKRFDTWWDKFRNRLANDGTFLDEVTKN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. :.:*. * .::.. .. : .::.:*: .:* . .::*: . :: :*.:.. ******:: . . ... :*:*:* :: * : :. : : * : * ::: :: . :: :* . . *: :*:.*: :: * . ", "identical_positions": 24, "similar_positions": 72, "identity": "9.56%" }, { "cls_id": "homologset.agr.SGD:S000005393", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RAI4-1", "uniprot_id": "M0RAI4_RAT", "id": "M0RAI4-1", "name": "Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial", "aln": "--------MAALRKSLLLAGPHVGALGHRVGRREASLGPDPGVTVRVRFAPSPTGFLHLGGLRTALYNYIFAKKHQGSFILRLEDTDQSRLVPGAAENIEDMLEWAGIPPDESPRQGGPAGPYYQSQRLALYAQATEALLKSGAAYPCFCSPQRLELLKKEALRSR--QTPRYDNRCRNLSQAQVAQKLATDPKPAIRFRLEEAVPAFQDLVYGWTQHEVASVEGDP-----VILKSDGFPTYHLACVVDDHHMSISHVLRGSEWLVSTSKHLLLYQALGWQPPQFAHLPLLLNRDGSKLSKRQGDIFLEHFAATGFLPEALLDIITNCGSG-FAE----NQMGRTLPELITQFDLTRITCHSALLDLEKLPEFNRLHLRRLVSSETQRPHLVEKLQGLVKEAFGSELQDRDVLDPAYMERILLLRQGHISRLQDLVSPVYSYLWTRPAVHRAELGASSEKLDVIAKHLLGLLERPGLSLTQDVVNRELKKLSEGLEGTKHSSVMKLLRMALSGQLQGPPVAEMMVSLGPEEVRERIQKPLWASHYRYLRKPEDGIGSPEAGVSDKATNPSMAEQDWSAIQKFCEQVNTDPSGPTHAPWLLAHKIQSPQEREALYALTVLEICMNHCGEKFHNEVAKFRFLNELIKVLSPKYLGAWATEKVKGRVIEILFSWTVWFPEDIKIRDAYQMLKKQGIIKQDPKLPMDKILPPPSPWPKSIFDADEEKSKLLTRLLKSNHPEDLQAANRLIKNLVKEEQEKSEKVSRRVSAVEEVRSHVRVLREMLSMYRRPGHALPDQQALQVVYERCEKLRPTLFRLASDTTDDDDALAEILQANDLLTQGVLLYKQVVEGRVNAGNAVPAAVGAIPASRVFPSPEPCGKNCPLIDLEAPSLLHQDLAALGINDVPTRNQVVIPSCCKDKKQPGAITLMGGGIQSLSADRNLLDLFSPQPSPGPLNYVPQKSIPKEVPPGTKASPGWSWEAGPLASSPASQNTPLAHVFVPLESVKPSSLPPIIVYDRNGFRILLHFSQTGAPGHPDVQVLLLTMMSTATQPVWDVMFQVAVPKSMRVKLQPASSSKLPAFSPLTPPAVISQMLLLDNPHKEPIRLRYKLTFNQGGQPFSEVGEVKDFPDLAVLSTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CXJ1-1", "uniprot_id": "SYEM_MOUSE", "id": "Q9CXJ1-1", "name": "Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial", "aln": "--------MAAPLKRLLLAEPHVVALGHRVGRREASLGPDPGAPVRVRFAPSPTGFLHLGGLRTALYNYIFAKKHQGSFILRLEDTDQSRLVPGAAESIEDMLEWAGIPPDESPRRGGPAGPYCQSQRLALYAQATEALLRSGAAYPCFCLPQRLELLKKEALRSR--QTPRYDNRCRNLSQAQVAQKLAVDPKPAIRFRLEEAVPAFQDLVYGWTQHEVASVEGDP-----VILKSDGFPTYHLACVVDDHHMSISHVLRGSEWLVSTSKHLLLYQALGWQPPRFAHLPLLLNRDGSKLSKRQGDIFLEHFAATGFLPEALLDIITNCGSG-FAE----NQMGRTLPELITQFDLTRITCHSALLDLEKLPEFNRLHLRRLVSSETQRPQLVEKLQGLVKEAFGSELQNKDVLDPAYMERILLLRQGHISRLQDLVSPVYSYLWTRPAVHRSELGASSENVDVIAKRLLGLLERPGLSLTQDVLNRELKKLSEGLEGAKHSSVMKLLRMALSGQLQGPPVAEMMVSLGPKEVRERIQKVLSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JPH6-1", "uniprot_id": "SYEM_HUMAN", "id": "Q5JPH6-1", "name": "Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial", "aln": "--------MAALLRRLLQRERPSAASGRPVGRREANLGTDAGVAVRVRFAPSPTGFLHLGGLRTALYNYIFAKKYQGSFILRLEDTDQTRVVPGAAENIEDMLEWAGIPPDESPRRGGPAGPYQQSQRLELYAQATEALLKTGAAYPCFCSPQRLELLKKEALRNH--QTPRYDNRCRNMSQEQVAQKLAKDPKPAIRFRLEQVVPAFQDLVYGWNRHEVASVEGDP-----VIMKSDGFPTYHLACVVDDHHMGISHVLRGSEWLVSTAKHLLLYQALGWQPPHFAHLPLLLNRDGSKLSKRQGDVFLEHFAADGFLPDSLLDIITNCGSG-FAE----NQMGRTLPELITQFNLTQVTCHSALLDLEKLPEFNRLHLQRLVSNESQRRQLVGKLQVLVEEAFGCQLQNRDVLNPVYVERILLLRQGHICRLQDLVSPVYSYLWTRPAVGRAQLDAISEKVDVIAKRVLGLLERSSMSLTQDMLNGELKKLSEGLEGTKYSNVMKLLRMALSGQQQGPPVAEMMLALGPKEVRERIQKVVSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0P499-1", "uniprot_id": "SYEM_DANRE", "id": "Q0P499-1", "name": "Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial", "aln": "--------MKILRG---------------VSRQMCTSRPE----VRVRFAPSPTGFLHLGGLRTALYNFLFSRQRRGVFILRLEDTDQKRLVPGAAEHIEDMLEWAGIPPDESSRRGGDYGPYVQSERLHLYTEAASSLLNTGHAYYCFCSNQRLELLKKEAQRSG--HAPRYDNRCRRLQPQQVEQKLAAGVPAVVRFKLHTGTEEFQDLVFGWTGHAVGAVEGDP-----VILKADGYPTYHLASVVDDHHMRISHVLRGCEWLISSAKHLQLYRALRWTPPTYAHLPLLLNRDGSKLSKRQGDIFLQSFRDRGVLPETLLDLVTHAGSG-FSD----NRMGRRLDELIRDFNISKITTHSALLDLDKLEEFSRLHLQRRIEDPQQCVWLCEELKQMVKHTHSSEISAAAVLEPEYIERVLQLRKGHISSLQDLLSSTHSYLWVRPRVSQTQLQSESAHAKDIATAVMQMVLAGGSLVSMERLSSELKQISSRTN-STHSSVMKVLRLLLSAQQRGPSVAEMMLSLGEQEVCVRLQKALEL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VV59-1", "uniprot_id": "Q9VV59_DROME", "id": "Q9VV59-1", "name": "Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial", "aln": "--------MLKINPR--------------MLMQQCLRHAHS--QVRVRFAPSPTGYLHLGGLRTALYNFLYARHLGGKFLLRIEDTDQTRLVPGASERLVEDLLWAGIEIDEGPGFGGQLGPYVQSQRTEIYSKAIEELLHNGTAYRCFCTERRLDLLRKEALRTR--QVPRYDNKCRHLTTSEVDSLLAKGTPYCIRFKLTDHEEPLDDLIYGKVHHNVSDNEGDP-----VVMKSDQFPTYHFANVVDDHLMGITHVLRGVEWQISTTKHLLLYKAFGWQPPKFGHLPLLVNADGTKLSKRQGDIGIQHFRERGYFPQALVNYVVSAGGG-FEHRTNAKQQLLSMQALHEQFHIERVNSHPSRLNPELLDDLNRLEIVQRLSGNESRTKLVNEVQQLVKEAYPQHSNLD--LAEEHILDVLNWSSKRLTLLQDLTSSKLSFLWVKP----SDFQIKDLTAEQLAH-LLQLIN-AIQDFHKDELNVKLKSFAQKEN-IKFPLMMKTLRAALSGLKEGPGVAEMMEILGKSVTLERLKEALPKESLHLEEHQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48525-1", "uniprot_id": "SYEM_YEAST", "id": "P48525-1", "name": "Glutamate--tRNA ligase, mitochondrial", "aln": "MIMLRIPTRSYCSPSKLIKGVGLSPLKKSLLSKKIKEDIHPSLPVRTRFAPSPTGFLHLGSLRTALYNYLLARNTNGQFLLRLEDTDQKRLIEGAEENIYEILKWCNINYDETPIK--------QSERKLIYDKYVKILLSSGKAYRCFCSKERLNDLRHSAMELKPPSMASYDRCCAHLGEEEIKSKLAQGIPFTVRFKSPERYPTFTDLLHGQINLQPQVNFNDKRYDDLILVKSDKLPTYHLANVVDDHLMGITHVIRGEEWLPSTPKHIALYNAFGWACPKFIHIPLLTTVGDKKLSKRKGDMSISDLKRQGVLPEALINFCALFGWSPPRDLASKKHECFSMEELETIFNLNGLTKGNAKVDDKKLWFFNKHFLQKRILNPSTLRELVDDIMPSLESIYN-----TSTISREKVAKILLNCGGSLSRINDFHDEFYYFFEKPKYNDNDAVTKFLSKNESRHIAHLLKKLGQFQEGTDAQEVESMVETMYYENGFSRKVTYQAMRFALAGCHPGAKIAAMIDILGIKESNKRLSEGLQFLQREKK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . **.********:****.*******:: ::: * *:**:*****.*:: ** * : : * *..* ** . **:* :* : . ** .* ** *** .**: *::.* . . **. * .: :: . ** . :**: : **:.* .* :::*:* ****:* ***** * *:**:** ** *:.**: **.*: * * : *:*** . ...*****:**: :. : * :*::*:: . * . . :: : * *.: :. : :: . * :.: : : : . * .: :: . : : :* : ::*: . :: . . : .: . : . : :* *:. *. :* *: ** . *:.: : ", "identical_positions": 123, "similar_positions": 130, "identity": "10.84%" }, { "cls_id": "homologset.agr.SGD:S000005394", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CG46-1", "uniprot_id": "SMC5_MOUSE", "id": "Q8CG46-1", "name": "Structural maintenance of chromosomes protein 5", "aln": "-MATPSGKAAPPNPQVSKRSLPRDASSEVPSKRKNSNPLPTLPRPSGTFVEGSIVRIAMENFLTYDICEVSPGPHLNMIIGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSKGLVEIELF------------RTSGNLIITREIDVIKNQSFWFINKKPVTQKIVEEQVAALNIQVGNLCQFLPQDKVGEFAKLSKIELLEATEKSVGPPEMHRYHCELKNFREKEKQLETSCKEKTEYLEKMVQRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEGVKLIRDRVKEEVRKLKEGQIPMTRRIEEIDRQRHTLEVRIKEKSTDIKEASQKCKQRQDLIERKDRQIKELQQALTVKQNEELDRQKRISNTRKMIEDLQSELKTAENCENLQPQIDTVTNDLRRVQEEKALCEGEIIDKQREKEMLEKQR--------RSVSDHITRFDNLMNQKEDKLRQRYRDTYDAVLWLRNNRDRFKQRVCEPIMLTINMKDNKNAKYVENHISSNDLRAFVFESQEDMEIFLREVRDNKKLRVNAVIAPKISYADKAPSRSLNDLKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVG------TERTRERIERVIQETRLKQIYTAEEKYVLKTSVYSN-KVISSNTSLKVAQFLTVTVDL-EQRRHLEEQLKEMNRQLEAVDSGLAALRDTNRHLELKDNELRLKKKELLERKTRKRQLEQKISSKLASIRLMEQDTCNLEEEERKASTKIKEINVQKAKLVTELTGLVKICTSFQIQKVDLILQNTTVISEKNKLEADYMASSSQLRVTEQQFIELDDNRQRLLQKCKELMKKARQVCNLSADQAVPQEFQTQVPTIPNGHSSSPPMAFQDLPNTLDEIDALLTEERSRASCFTGLNPSVVEEYSKREVEIQQLTEELQGKKVELDEYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHTENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDEINQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEPNRWNLKAFQRRRRRITFTQPQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LTW9-1", "uniprot_id": "A0ABK0LTW9_RAT", "id": "A0ABK0LTW9-1", "name": "Structural maintenance of chromosomes protein 5", "aln": "-MATPSGKAAAPNPQASKRSLPRDASSEFPSKRKNSNPTSTLPRPSGLFVEGSIVRIAMENFLTYDICEVSPGPHLNMIIGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSKGLVEIELF------------RTSGNLIITREIDVIKNQSFWFINKKPVTQKIVEEQVAALNIQVGNLCQFLPQDKVGEFAKLSKIELLEATEKSIGPPEMHRYHCELKNFREKEKQLETSCKEKTEYLDKMIQRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEGVKLVRDRVKEEVRKLKEGQIPMTRRIEEIERQRRTLEVRIKEKATDIKEASQKCKQRQDLIERKDRHIKELQQALTVKQNEEQDRQKRISNTRKMIEDLQNELRTAENCENLQPQIDAITNDLRRVQEEKALCEGEIIDKQREKEMLEKQK--------RSVSDHITRFDNLMNQKEDKLRQRYRDTYDAVLWLRNNRDRFKQRVCEPIMLTINMKDNKNAKYVENHISSNDLRAFVFESQEDMEIFLREVRDNKKLRVNAVIAPKISYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVG------TERTRERIERVIQETRLKQIYTAEEKYVLKTSFYSN-KVISSNTSLKVAQFLTVTVDL-EQRRHLEEQLKEINRKLEAVDSGLVALRDTNRHLELKDNELRLKKKELLERKTKKRQLEQKISSKLASIRLMEQDTCNLEEEERKASTKIKEINVQKAKLVTELTGLVKICTSLHIQKVDLILQNTTVISEKNKLEADYMASSSQLRVTEQQFIELDDNRQRLLQKCKELMKRARQVCNLSADQAVPQEFQTQVPTIPNGHSSSPPMAFQDLPNTLDEIDALLTEERSRASCFTGLNPSVVEEYTKREIEIQQLTEELKGKKVELDEYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHTENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDEINQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEPNRWNLKAFQRRRRRITFTQPSQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IY18-1", "uniprot_id": "SMC5_HUMAN", "id": "Q8IY18-1", "name": "Structural maintenance of chromosomes protein 5", "aln": "-MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMENFLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSRGMVEIELF------------RASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLPQDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMVQRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLKEGQIPVTCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALIVKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGEIIDKRRERETLEKEK--------KSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQRVCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIAPKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVG------TEKTRERIERVIQETRLKQIYTAEEKYVVKTSFYSN-KVISSNTSLKVAQFLTVTVDL-EQRRHLEEQLKEIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKLMEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISEKNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQTQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEIEQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHTENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDEINQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEPNTWNLKAFQRRRRRITFTQPS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IPT2-1", "uniprot_id": "Q8IPT2_DROME", "id": "Q8IPT2-1", "name": "Structural maintenance of chromosomes protein 5", "aln": "--------------MAGDRALSSKQ------------------------LAGRIHSVYCKDFVSYSEITFHPKHYLNVLTGPNGSGKSTIVSAIILGLGGEPILLDRSASVADYIQSNKTSATIIVRVYG-----------RTPNTTETFRRIINSNGLSTFSVNDKDTSKKNFLAAVSSFNIQVSNLCQFLPQDRVQDFSKMNPQELLLNTMSSVCDEDLINSFNSLKQMRTEQANVHANREKEKSDLVKKQKRLEHLQMTVSQYKEREEVKQKLQVYSAKKLWVETQAGEAKAAEMKTQVKNAKTQSDKLKNQHDKLLQSQEQIEKEKESLRKALLEKTRLLENAVAEKAAIDGKMDSLKQGIYQKKYELEQNIKKSRRTATECDNLNQLVENKIYELETLNKSR------PLIVSELERAKESCAAARGKAMEQYSRRRQLEQKLNDEMIPEITAYKLKIERLRNVKMQKIDEIRAKNPNLVVAMNWLAQNKQRYKLNVYDPMILELTVQNHEDAKFLENVVAQRDLFAFACEDKGDMSDLINELCVKQKLGVNVIYCAPSDRLVYSPKTPIDDLRSFGFRSYLVDLVTGPIPLINKLCASYSIHNIPIG------TEAVGNYTSSIPKAIR--VYFGGSKKFVVTASRYRS-DTILTESSIRAKNQL-ITVDS-QQLALVMKQCSEAVKESDSIKNAITQTDNEFERLQAVAKDEQEKRRKLDQKIAHFNSLKTEIETLQKKLEALRNSDS-LDCLETNFCNSLHKDLKKIFDADAELCSCLKAIDRLIIEKNMAQTKVSIYMLQHETQIEALKESEEQSKAATRDFQQLLQCLENQISDVNKRKSAIQGLCHGEIPTSSKFPFKKEFRELEN--------------IDLPELREAIHDFQARLECMKSVNSEAISSYQGLQNEVKQLEEGIQESVNQAKSIESGMSNLYDKWEPKLNSLVETISTKFSEFMESIEYVGEVVLSKTDKYDFDSYGIQIMVQFRRGLQLQPLDKFIQSGGERAVSIAIYSLSLQHVTHVPFRCVDEINQGMDATNERHIFDLLLKEATKHGSAQYLFVTPKLLRDLNYNEHLCVSIVHNSKTVCHGMQFPMA----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08204-1", "uniprot_id": "SMC5_YEAST", "id": "Q08204-1", "name": "Structural maintenance of chromosomes protein 5", "aln": "MTSLIDLGRYVERTHHGEDTEPRSKRVKIAKPDLSS------------FQPGSIIKIRLQDFVTYTLTEFNLSPSLNMIIGPNGSGKSTFVCAVCLGLAGKPEYIGRSKKVEDFIKNGQDVSKIEITLKNSPNVTDIEYIDARDETIKITRIITRSKRRSDYLINDYQVSESVVKTLVAQLNIQLDNLCQFLSQERVEEFARLKSVKLLVETIRSIDAS-LLDVLDELRELQGNEQSLQKDLDFKKAKIVHLRQESDKLRKSVESLRDFQNKKGEIELHSQLLPYVKVKDHKEKLNIYKEEYERAKANLRAILKDKKPFANTKKTLENQVEELTEKCSLKTDEFLKAKEKINEIFEKLNTIRDEVIKKKNQNEYYRGRTKKLQATIISTKEDFLRSQEILAQTHLPE------KSVFEDIDIKRKEIINKEGEIRDLISEIDAKANAINHEMRSIQRQAESKTKSLTTTDKIGILNQDQDLKEVRDAVLMVREHP-EMKDKILEPPIMTVSAINAQFAAYLAQCVDYNTSKALTVVDSDSYKLFANPILDKFKVNLRELSS-----ADTTPPVPAETVRDLGFEGYLSDFITGDKRVMKMLCQTSKIHTIPVSRRELTPAQIKKLITPRPNGKILFKRIIHGNRLVDIKQSAYGSKQVFPTDVSIKQTNFYQGSIMSNEQKIRIENEIINLKNEYNDRKSTLDALSNQKSGYRHELSELASKNDDINREAHQLNEIRKKYTMRKSTIETLR---EKLDQLKREARKDVSQKIKDIDDQIQQLLLKQRHLLSKMASSMKSLKNCQKELISTQILQFEAQNMDVSMNDVIGFFNEREADLKSQYEDKKKFVKEMRDTPEFQSWMREIRSYDQDTKEKLNKVAEKYE---EEGNFNLSFVQDVLDKLESEIAMVN-HDESAVTILDQVTAELRELEHTVPQQSKDLETIKAKLKEDHAVLEPKLDDIVSKISARFARLFNNVGSAGAVRLEKPK--DYAEWKIEIMVKFRDNAPLKKLDSHTQSGGERAVSTVLYMIALQEFTSAPFRVVDEINQGMDSRNERIVHKAMVENACAENTSQYFLITPKLLTGLHYHEKMRIHCVMAGSWIPNPSEDPKMIHFGETSNYSFD----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : . . * * : ::*::* . **:: *.**:***::*.*: ***.*:* :.*: .* ::: . . : : : . * * : * : :*. .::. . *: :***:.******.*::* :*:::. :** * *: : .*:::: :: .:. . . :. : : :. :: : *. : :. ::: . :*: : . : * ...* : : : : . : ::.: . * *: : :* : :: : : : . . .: . * . . : .:: :.. .*: : . : . : : . : : *: : :: . * .: :* :: :. : : * :: : : . *:. .. . . : . : : *: :. : . :* . : ::. ** .** ::. . ::. ** ** :*:. :: ... :. * * . ..: :: *:: : :: :* : :: : .: : .. : : . .: *. .: .. : ..:. : .:. :. *: : : ..: : . . :* : .. : : . : . . . . * : : .. :: . : . :. : * * : : . .:. .. : : *:.:* . : . : . . :.: *..:*..*. :*:.::..: .* * * . . *: .: *.* *:** . *: * . ******:** :* ::**... *** *********. *** :.. ::: * ..::**:::***** .* * *:: : * . : . ", "identical_positions": 133, "similar_positions": 348, "identity": "11.76%" }, { "cls_id": "homologset.agr.SGD:S000005398", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M6I7-1", "uniprot_id": "F1M6I7_RAT", "id": "F1M6I7-1", "name": "Proteasome subunit alpha type", "aln": "MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVR-KICALDDHVCMAFA------GLTADARVVISRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISALIVGFD-DDGIPRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYT-EDAISNDNEAIKLAIKALLEVVQSGGKNIELAIIRRDQPLKMFSAKEIELEVTEIEREKDEA-EKKKSKKST-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWH6-1", "uniprot_id": "PSMA8_MOUSE", "id": "Q9CWH6-1", "name": "Proteasome subunit alpha type-8", "aln": "MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVR-KICALDDHVCMAFA------GLTADARVVISRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISALIVGFD-DDGIPRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYT-EDAISNDKEAIKLAIKALLEVVQSGGKNIELAIIRRDQPLKMFSAKEIELEVSEIEREKDEA-EKTKSKKST-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TAA3-1", "uniprot_id": "PSMA8_HUMAN", "id": "Q8TAA3-1", "name": "Proteasome subunit alpha-type 8", "aln": "MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVR-KICALDDHVCMAFAVLTIFIGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISALIVGFD-DDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYT-EDAIASDSEAIKLAIKALLEVVQSGGKNIELAIIRRNQPLKMFSAKEVELYVTEIEKEKEEA-EKKKSKKSV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O14818-1", "uniprot_id": "PSA7_HUMAN", "id": "O14818-1", "name": "Proteasome subunit alpha type-7", "aln": "MS--YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVR-KICALDDNVCMAFA------GLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFD-FDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYT-DEAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNPEEIEKYVAEIEKEKEEN-EKKKQKKAS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48004-1", "uniprot_id": "PSA7_RAT", "id": "P48004-1", "name": "Proteasome subunit alpha type-7", "aln": "MS--YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVR-KICALDDNVCMAFAVVASVSGLTADARIVINRARVECQSHRLTVGDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFD-FDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYT-DDAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQPLKILSPEEIEKYVAEIEKEKEEN-EKKKQKKAS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2U0-1", "uniprot_id": "PSA7_MOUSE", "id": "Q9Z2U0-1", "name": "Proteasome subunit alpha type-7", "aln": "MS--YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVR-KICALDDNVCMAFA------GLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFD-FDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYT-DDAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQPLKILNPEEIEKYVAEIEKEKEEN-EKKKQKKAS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40303-1", "uniprot_id": "PSA4_YEAST", "id": "P40303-1", "name": "Proteasome subunit alpha type-4", "aln": "MSG-YDRALSIFSPDGHIFQVEYALEAVKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITPSKVSKIDSHVVLSFS------GLNADSRILIEKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQRYTQSGGVRPFGVSTLIAGFDPRDDEPKLYQTEPSGIYSSWSAQTIGRNSKTVREFLEKNYDRKEPPATVEECVKLTVRSLLEVVQTGAKNIEITVVKPDSDIVALSSEEINQYVTQIEQEKQEQQEQDKKKKSNH", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P22769-1", "uniprot_id": "PSA71_DROME", "id": "P22769-1", "name": "Proteasome subunit alpha type-7-1", "aln": "MSSRYDRAVTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKKSVAQLQEDRKVR-KICMLDNHVVMAFA------GLTADARIMINRAQVECQSHRLNVEDPVTLEYITRFIAQLKQKYTQSNGRRPFGISCLIGGFD-ADGSAHLFQTEPSGIFYEYKANATGRSAKVVREFFEKSYREEE-VANEHGAVKLAIRALLEVAQSGQNNLEVAIMENGKPLKMLDTDVITDYVKIIEKEKEEELEKKKQKK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q24178-1", "uniprot_id": "PSA72_DROME", "id": "Q24178-1", "name": "Proteasome subunit alpha type-7-1A", "aln": "MSSRYGRALTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKSSVSEMQEDRTVR-KISMLDRHVALAFA------GLTADARILINRGQVECQSHRLNFENQVTLEYITRYLAQLKQKYTQCNGRRPFGISCLIGGID-ADGSARLFHTEPSGIFHEYKATATGRWANTVREFFEKAYSDHE-VTTKCDAIKLAMRALLEVTQMSQMRLEVAVLENGKPMKMLDSVVISEIVKIVQNEKELQAKAHKMKR---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q27575-1", "uniprot_id": "PSA73_DROME", "id": "Q27575-1", "name": "Proteasome subunit alpha type-7-1B", "aln": "MAQRYDRAVTIYSPDGHLLQVEYAQEAVRRGSTVMGLRTNNAIVIGVEKRSVGDLQEERMVR-KICMLDDHVVMTFS------GLTADARILVSRAQMEAQSHRLNFEKPTTVEYITRYIAQLKQNYTQSNGRRPFGLSCLVGGFD-EDGTPHLFQTDPSGIFYEWRANTTGRSSQPVRDYMEKHADEILTIADEAAAIKHIVRTLVSVSSLNHTQMEVAVLKYRQPLRMIDHQVLADLERTVRREIEDEAEASRRPRAP-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *.**::::*****::***** ***::*: .:*:: : :*:* *: *. .:*: * . *:. :* :* ::*: **.**:*:::.:.::*.***:*.. . .*:**:**::* ::*.***..* ****:* *: *:* *. .:*::*:*** : : * : ** :: **:::** :* :::*:.* . . .:*::::. . : :. : :..* : : : : ", "identical_positions": 76, "similar_positions": 100, "identity": "29.12%" }, { "cls_id": "homologset.agr.SGD:S000005399", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A4D5-1", "uniprot_id": "D4A4D5_RAT", "id": "D4A4D5-1", "name": "Large ribosomal subunit protein P2", "aln": "MRYVASYLLAALGGNSNPSAKDIKKILDSVGIEADDERLNKVISELNGKNIEDVIAQGVGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDEDMGFGLFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P02401-1", "uniprot_id": "RLA2_RAT", "id": "P02401-1", "name": "Large ribosomal subunit protein P2", "aln": "MRYVASYLLAALGGNSNPSAKDIKKILDSVGIEADDERLNKVISELNGKNIEDVIAQGVGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDDDMGFGLFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZN03-1", "uniprot_id": "D3ZN03_RAT", "id": "D3ZN03-1", "name": "Large ribosomal subunit protein P2", "aln": "MRYVASYLLAALGGNSNPSAKDIKKILDSVGIEAEDERLNKVISELNGKNIEDVIAQGVGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDDNMGFDLFN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05387-1", "uniprot_id": "RLA2_HUMAN", "id": "P05387-1", "name": "Large ribosomal subunit protein P2", "aln": "MRYVASYLLAALGGNSSPSAKDIKKILDSVGIEADDDRLNKVISELNGKNIEDVIAQGIGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDDDMGFGLFD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P99027-1", "uniprot_id": "RLA2_MOUSE", "id": "P99027-1", "name": "Large ribosomal subunit protein P2", "aln": "MRYVASYLLAALGGNSSPSAKDIKKILDSVGIEADDDRLNKVISELNGKNIEDVIAQGVGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDDDMGFGLFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A5F8MPY2-1", "uniprot_id": "A0A5F8MPY2_MOUSE", "id": "A0A5F8MPY2-1", "name": "Large ribosomal subunit protein P2", "aln": "MRYVASYLLAALGGNSSPSAKDIKKILGSVGIEADDDRLNKVISELNGKNIEDVIAQGVGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDDDMGFGLFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05389-1", "uniprot_id": "RLA2_DROME", "id": "P05389-1", "name": "Large ribosomal subunit protein P2", "aln": "MRYVAAYLLAVLGGKDSPANSDLEKILSSVGVEVDAERLTKVIKELAGKSIDDLIKEGREKLSSMPVGGGGAVAAAD--AAPAAAAGGDKKEAKKEEKKEESESEDDDMGFALFE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05319-1", "uniprot_id": "RLA2_YEAST", "id": "P05319-1", "name": "Large ribosomal subunit protein P2A", "aln": "MKYLAAYLLLNAAGN-TPDATKIKAILESVGIEIEDEKVSSVLSALEGKSVDELITEGNEKLAAVPAAG--PASAGG----AAAASGDAAAEEEKEE--EAAEESDDDMGFGLFD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*:*:*** .*: .* ..:: ** ***:* : :::..*:. * **.::::* :* **:::*..* ..:*. .**.:. * :*:* * :*..*::*** **:", "identical_positions": 38, "similar_positions": 46, "identity": "33.04%" }, { "cls_id": "homologset.agr.SGD:S000005400", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62841-1", "uniprot_id": "RS15_HUMAN", "id": "P62841-1", "name": "Small ribosomal subunit protein uS19", "aln": "MAEVEQKKKRTFRKFTYRGVDLDQLLDMSYEQLMQLYSARQRRRLNRGLRRKQHSLLKRLRKAKKEAPPMEKPEVVKTHLRDMIILPEMVGSMVGVYNGKTFNQVEIKPEMIGHYLGEFSITYKPVKHGRPGIGATHSSRFIPLK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62845-1", "uniprot_id": "RS15_RAT", "id": "P62845-1", "name": "Small ribosomal subunit protein uS19", "aln": "MAEVEQKKKRTFRKFTYRGVDLDQLLDMSYEQLMQLYSARQRRRLNRGLRRKQHSLLKRLRKAKKEAPPMEKPEVVKTHLRDMIILPEMVGSMVGVYNGKTFNQVEIKPEMIGHYLGEFSITYKPVKHGRPGIGATHSSRFIPLK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62843-1", "uniprot_id": "RS15_MOUSE", "id": "P62843-1", "name": "Small ribosomal subunit protein uS19", "aln": "MAEVEQKKKRTFRKFTYRGVDLDQLLDMSYEQLMQLYSARQRRRLNRGLRRKQHSLLKRLRKAKKEAPPMEKPEVVKTHLRDMIILPEMVGSMVGVYNGKTFNQVEIKPEMIGHYLGEFSITYKPVKHGRPGIGATHSSRFIPLK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01855-1", "uniprot_id": "RS15_YEAST", "id": "Q01855-1", "name": "Small ribosomal subunit protein uS19", "aln": "MSQAVNAKKRVFKTHSYRGVDLEKLLEMSTEDFVKLAPARVRRRFARGMTSKPAGFMKKLRAAKLAAPENEKPAPVRTHMRNMIIVPEMIGSVVGIYNGKAFNQVEIRPEMLGHYLGEFSITYTPVRHGR--AGATTS-RFIPLK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::. : ***.*:..:******::**:** *::::* .** ***: **: * .::*:** ** ** *** *:**:*:***:***:**:**:****:******:***:***********.**:*** *** * ******", "identical_positions": 88, "similar_positions": 35, "identity": "60.69%" }, { "cls_id": "homologset.agr.SGD:S000005401", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C5L7-1", "uniprot_id": "RBM34_MOUSE", "id": "Q8C5L7-1", "name": "RNA-binding protein 34", "aln": "------MALGGEE-RKRRKGSERRQSSGDGV-SCAASDYLVGQVADSLRGGPRPPGGGTGRLAALFSTAEPSAPPVFVPVPQETSKKRKLDDDDDDEEESVSQTKKP-VLQEPSRKVKVKKLS-DADKRLANRESALASADLEEELHQDQGQGRRRRSQSRGKVADGEALDVALSLAKDGGQRTKIPVNPEEERLKNERTVFVGNLPVTCNKKKLKSFFKEYGQVESVRFRSVMPAEGTLTKKLAAIKRKFHPDQKSINAYVVFKDESAAAKALQRNGAQIAEGFR----------IRVDLASETASRDKRS-VFVGNLPYKIEDSALEEHFLDCGSIVAVRIVRNPLTGVGRGFGYVLFENTDAVHLALKLNNSELMG---------------RKLRVMRSVNKEK-------LKQQNSNPSLKKDVIKPKQRLNFTSKEGKFHSKEGKFHSKNAFIGEKAVLMKKKKKGQKKKVQMKKPRKQQ---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M9F1-1", "uniprot_id": "RBM34_RAT", "id": "Q5M9F1-1", "name": "RNA-binding protein 34", "aln": "------MALRGEG-RKRKKGQERRQSSEDDV-GNAATDYLVGQVADSLRGGARPPGGGTGRLAALFSTPETLAPPVFVPVPQETSKKRKPDD----EEETVAHIKKP-ALQEPARKVKVKKLS-DADKRLANRESALANADL-EEIRQDQGQGRRR-SQSRGKVTDGEALDVALSLNEDGRQRTKVPLNPEEERLKNERTVFVGNLPVTCNKKKLKSFFKEYGQVESVRFRSVMPAEGTLSKKLAAIKRKFHPDQKSINAYVVFKEERAAAKALQRNGAQIAEGFR----------IRVDLASETASRDKRS-VFVGNLPYRVDESALEEHFLDCGSIVAVRIVRNPLTGVGRGFGYVLFENTDAVHLALKLNNSELMG---------------RKLRVMRSVNKEK-------LKQQNSNPSVKKDGSKSKQRLNFTSKEG-------KSHSKNAFIGEKAVLMKKKK-GQKKKGQTKKPRKQK---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZZE4-1", "uniprot_id": "A0A8I5ZZE4_RAT", "id": "A0A8I5ZZE4-1", "name": "", "aln": "------MALGGEG-QKRKK--ERRQSSE------CSHQPPGGTGCQQLVASTHPPGGGTGQLAALFSTPETSAPPVFVPVPQETSKKRKLDD----EEESVAHVKRPPVLQEPARKVKVKKLF-DADKRLANRESALSNADL-EEIHQDQGQARRR-SQSRGKAADGEALDVALSLNEDGDKRTKVPLNPEEEQLKNERTVFVGNLPVTCNKKKLKSFFKEYGQVESTRFHSVMPAEGTLSKKLAAIKRKFPPDQKSINAYVVFKEESAAAKALSRNGAQTAEGFR----------IALIWHLKLP-LGTRD-QFLWEISLTKWKSLLWRNTLDCGSIVAVRTVRNPLTGVGRGFGYVLFENTDAVHLALKLNNSELMG---------------RKLRVMGSVNKEK-------LKQQNSNPSLKKDVSKSKQRLNFTSKEG-------KFHSKNAFIGEKAVLVKKKK-GQKKKGQTKKPRKHK---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42696-1", "uniprot_id": "RBM34_HUMAN", "id": "P42696-1", "name": "RNA-binding protein 34", "aln": "------MALEGMSKRKRKRSVQEGENPDDGVRGSPPEDYRLGQVASSLFRGEHHSRGGTGRLASLFSSLEPQIQPVYVPVPKQTIKKTKRNE----EEESTSQIERP-LSQEPAKKVKAKKKHTNAEKKLADRESALASADLEEEIHQKQGQKRKN-SQPGVKVADRKILDDTEDTVVS--QRKKIQINQEEERLKNERTVFVGNLPVTCNKKKLKSFFKEYGQIESVRFRSLIPAEGTLSKKLAAIKRKIHPDQKNINAYVVFKEESAATQALKRNGAQIADGFR----------IRVDLASETSSRDKRS-VFVGNLPYKVEESAIEKHFLDCGSIMAVRIVRDKMTGIGKGFGYVLFENTDSVHLALKLNNSELMG---------------RKLRVMRSVNKEK-------FKQQNSNPRLKN-VSKPKQGLNFTSKTA-------EGHPKSLFIGEKAVLLKTKKKGQKKSGRPKKQRKQK---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08208-1", "uniprot_id": "NOP12_YEAST", "id": "Q08208-1", "name": "Nucleolar protein 12", "aln": "MSSAIDNLFGNIDEKKIESSVDKLFSSSCGPINKLEVKSKTRTVLPDSKKRERAAEADQEEKEASKPDVSDEQTEEVALPKVKKAKKSKRND----EDEDLEARYYAKLLNEEAEAEDDKPTVTKTDETSVPLTSAAKKVDFKEDELEKAER----------TVFIGNILSTVITSKKVYKEFKKLFGTNPIAETEES-----GNEKEEESSKKSD---NNEFAIESIRFRSIS-FDEALPRKVAFVQQKFHKSRDTINAYIVYKNKSAVRKICSNLNAVVFQDHH----------LRVDSVAHPAPHDKKRSIFVGNLDFEEIEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDLQSVNKALLLNEKPMKSQKQEDENTKKPTKKARKLRVSRCKNMKKGTTIGTGLDRNGLTDSQRTRAGRAKKILGKADRATLG--QEITIEGLRAKKGEGSTHLKKKKQRSATGRVTKRSIAFKKAQAEKSKK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VJG2-1", "uniprot_id": "Q9VJG2_DROME", "id": "Q9VJG2-1", "name": "RRM domain-containing protein", "aln": "--------MKTPKAKESEKAELKPIKKEPG----VVEDGKVTKKSKTKPKKKTVKVPKDEVKAAVQESPKKLSAKDLAKIEKKKAKK------------------QAQKLKKQQNKLAPKEIKTEPEAQVKVESKATKKEKVEKEPTTAPNEKPKG--------------KVSKKAKANANNKDEEGVKRIRNPAEEASTVFVGNLPINTKRVQLVKLFQPYGLVQSIRLRTAG--------GKQLFKHKQRKVAGSLNAYVVLEKPEIAQQALALNGSEFKENHLRVTPASMAEKFGQAKDKQPSDKDAKRTIFVGSLKYSATEEQLREIFSSCGEIDYIRCLQDGDKGC-KGVAYVCFQKPDAVGLALELNQTLLDDRPINVERYQVKKLGAKQVRDAAAASAASKTSSKTKAKNQNSAGAKKRLDKKKGKENGSLKKEGAP----TGQKKKSEYRGVKVDGIKKAKKPKKKSNDQQTALAKKIAPKQKS--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: . . . . : . . :. ** . :: . * ..: .* . .. :: . . : : . :: ** . : : ::* *::: .::* .:***:* :. . : .: :.. : . . . : *: .: .. : . **.* :* ::: .. :*..** *:. ::* ** **:. : . :::* . . . ..:. : : : . .: . * :*. * . . : : ", "identical_positions": 31, "similar_positions": 108, "identity": "6.28%" }, { "cls_id": "homologset.agr.SGD:S000005403", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A4E8-1", "uniprot_id": "D4A4E8_RAT", "id": "D4A4E8-1", "name": "Endonuclease III-like protein 1", "aln": "MNSG-LRIVTRSRSRATR-----------------------------IASEGCR----------------------------EELAP---RETAAEGRKSHKPVRR--------------------PRKKQKVHVAYEVANGEEGEDAEPLKVPVWEPQ-NWQQQLANIRIMRSKKDAPVDQLGAEQCYDIT----------APPKVRRYQVLLSLMLSSQTKDQVTAGAMQRLRA---------RGLTVESILQTDDDLLGRLIYPVGFWRSKVKFIKQTTAILQQRYEGDIPASVAELVALPGVGPKMAHLAMAVAWGTVSGIAVDTHVHRIANRLKWTK-KMTKSPEETRRNLEEWLP----SEINGLLVGFGQQICLPVHPRCQACLNKALCPAAQGL---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35980-1", "uniprot_id": "NTH_MOUSE", "id": "O35980-1", "name": "Endonuclease III-like protein 1", "aln": "MNSG-VRMVTRSRSRATR-----------------------------IASEGCR----------------------------EELAP---REAAAEGRKSHRPVRH--------------------PRRTQKTHVAYEAANGEEGEDAEPLKVPVWEPQ-NWQQQLANIRIMRSKKDAPVDQLGAEHCYDAS----------ASPKVRRYQVLLSLMLSSQTKDQVTAGAMQRLRA---------RGLTVESILQTDDDTLGRLIYPVGFWRNKVKYIKQTTAILQQRYEGDIPASVAELVALPGVGPKMAHLAMAVAWGTISGIAVDTHVHRIANRLRWTK-KMTKTPEETRKNLEEWLPRVLWSEVNGLLVGFGQQICLPVHPRCQACLNKALCPAAQDL---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78549-2", "uniprot_id": "NTH_HUMAN", "id": "P78549-2", "name": "Endonuclease III-like protein 1", "aln": "MTALSARMLTRSRSLGPG-----------------------------AGPRGCR----------------------------EEPGPLRRREAAAEARKSHSPVKR--------------------PRKAQRLRVAYEGSDSEKGEGAEPLKVPVWEPQ-DWQQQLVNIRAMRNKKDAPVDHLGTEHCYDSS----------APPKVRRYQVLLSLMLSSQTKDQVTAGAMQRLRA---------RGLTVDSILQTDDATLGKLIYPVGFWRSKVKYIKQTSAILQQHYGGDIPASVAELVALPGVGPKMAHLAMAVAWGTVSGIAVDTHVHRIANRLRWTK-KATKSPEETRAALEEWLPRELWHEINGLLVGFGQQTCLPVHPRCHACLNQALCPAAQGL---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIH0-1", "uniprot_id": "Q9VIH0_DROME", "id": "Q9VIH0-1", "name": "Endonuclease III homolog", "aln": "MAKN-VKKLTLANKLAKRGDLIKPTEIKSRPNRADNVRDIEDLVGVSAGAAGSSSSVFFSPVQTRKQRLLNGEAVKKTNIKMEPLSP--ARVAPKKFRKDDRMVTRVQMGSATVVICKVVPDAVDSPVRVDKIREEVEPQIKQEAPEDSPSFSEVQAPHPLWFNHLENIRIMRNSRTAPVDTMGCHRCADLK----------ADSKTQRFQNLVALMLSSQTKDQTTYEAMNRLKD---------RGLTPLKVKEMPVTELENLLHPVSFYKNKAKYLKQTVEILTDKYGSDIPDNVKDLVALPGVGPKMAHICMAVAWNKITGIGVDVHVHRLSNRLGWVP-KPTKEPEQTRVALEKWLPFSLWSEVNHLFVGFGQTICTPVKPNCGECLNKDICPSAHAETKEKRKKDR------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08214-1", "uniprot_id": "NTH2_YEAST", "id": "Q08214-1", "name": "Endonuclease III homolog 2", "aln": "-----MREESRSRKRKHIP--------------------------VDIEEVEVRS---------------------------KYFKK---NERTVELVKENKINKDLQNYGGVNIDWIKALKPIEYFEWIESRTCDDPRTWGRPITKEEMINDSGAKVPESFLPIYNRVRLMRSKVKTPVDAMGCSMIPVLVSNKCGIPSEKVDPKNFRLQFLIGTMLSAQTRDERMAQAALNITEYCLNTLKIAEGITLDGLLKIDEPVLANLIRCVSFYTRKANFIKRTAQLLVDNFDSDIPYDIEGILSLPGVGPKMGYLTLQKGWGLIAGICVDVHVHRLCKMWNWVDPIKCKTAEHTRKELQVWLPHSLWYEINTVLVGFGQLICMARGKRCDLCLANDVCNARNEKLIESSKFHQLEDKEDIEKVYSHWLDTVTNGITTERHKKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :.. : . . : *.. : . . : .:* **.. :*** :* . .* * * *:. ***:**:*: * .: .*:* : : * .*: *.*: *.:::*:* :* :.: .*** .: :::********.:: : .*. ::** **.****:.: *. * .*.** *: *** *:* ::***** * . .* ** : :* : : ", "identical_positions": 70, "similar_positions": 78, "identity": "15.87%" }, { "cls_id": "homologset.agr.SGD:S000005405", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CEE6-1", "uniprot_id": "PASK_MOUSE", "id": "Q8CEE6-1", "name": "PAS domain-containing serine/threonine-protein kinase", "aln": "MEDRGPPVFAEDWKCLSESPP---VQEGPAAQATFEPSKPLSIAHKHLSRKNGLSR-LCQSRMALSEDRWSSYCLSSLAAQNICTSKLHCAAAPEYADPTAGPLGSTSCCSLLRGLASGCSGSLLSTPVCNPNKAVFTVDAKTTEILVANDKACSLLGYSSHDLIGQKLAQFFLKSDSEVVEALSEEHVEADGHAAVVFGTV---------------------VDIVSRIGEKIPVSVWIKRLQQDRGLCCVVVLEPVERVSAWVAFQSDGTITSCDSLFAHLHGFTSPKDVVGQCVIDLIPSMQLPPPGQHIPKSLKIQRSVGRARDGTTFPLSLKLKSKPSGRAVADSEAASEPGYQASVWVFCTISGLITLLPDGTIYGVNHSFALMLFGYGKTELLGKNITFLIPGFYHYMDLTYDSSVQLPDLVNCLDIGRKSGPGEMNSDAQHNWELASGAQGPRIDVVLARDHMPSQDETLKLVGGQ-VSSRTQTRLETGYKILPSSACQPSLGVDSNPEDGEQSLLTDQQSIPKRNLPAHGG----QNQLDTSEISLPVLKEHLLSEIQKNISEESPLTHRKWLS-KVQQNPTKGSLPIHEEQLLFAGQHIHVLGKEDPSAAESYRESLLEESKSKPVDAKLFASCEDSEPLVSVKDRGSSVDTCNLHQEAQLELMGVSSP---NPWADATMPEPHTTGQIAGGS-LTYCPQYRSEWASQQRGQDSAPSPSGMACVLLGTPTLDEPWPGVRNDREELQTCLIKEQLSKSSCEGNLGISRVELVPEEHPPFTAPVSFCDLGGRDLHASRSGSSSACYALATDLPGVLEAVEAQEADVNSYSWNLKELFLKDQTDRTPSHCSCTTSELSEAPSLSVVGSDLDVGILHRQTSDILVDREMLLLTGTYFDLSEGQRFQEMGAGHDRAELSNISLVSSEHYETSDIESPGCDPPLPDPGPNDMCLSAEKPRPSAQITSTP--VARGATSLQQEIQEGIYSGSCYHRDGLQLSIQFEVKRVELQGSATLFCCWLVKDLFHSHRDSATRTRLFLASLPSSTHS-MPELSGSSFGEVLRAKPWFEESPTPAELEGLAACEGEYDYKYNTISPLGSGAFGFVWTAVEKECNKEVVVKFIKKEKVLEDCWIEDPKLGRVTLEIAILSKVDHAN---IIKVLDIFENQEFFQLVMEKHGSG--MDLFAFIDHHPCLDEPLASFIFRQLVSAVGYLHSQGIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLIGNPYRGPELEMWSLGVTLYTLIFEENPFCEVEETMEAVIHP--PFLVSQELMSLLSGLLQPCPEQRTTLEKLIRDPWVTQPVNLASYTWEEVCRTNQPESGLLSAASLEIGSRSPSEMAQREGLCGPPAPRETRGDQHCLHLKDPSLPVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LLF4-1", "uniprot_id": "A0ABK0LLF4_RAT", "id": "A0ABK0LLF4-1", "name": "PAS domain-containing serine/threonine-protein kinase", "aln": "MEDRGPPVLAEDWK--SESLP---AQEGPATQAFVEPSKPLSIAHRHLNRKNGLSR-LCQSRMALSEDRWSSYCLSSLAAQNICTSKLHCAATPDYADPIAGPLGSTSCCSLLRGLASGCSGPLLSTPVCNPNKAVFTVDAKTTEILVANDKACSLLGYSSHDLIGQKLTQFFLKSDSEVVEALSEEHVEADGHAAVVFGTVAPASHSRMILSSWSTDSPILSVDIVSRSGEKIPVSVWIKRLQQDRGLCCVVVLEPVERVSAWVAFQSDGTITSCDSLFAHLHGFTSPKDVVGQCVIDLIPSIQLPPPGQHVPKSLKIQRSVGRARDGTTFPLSLKLKSKTSGKAVAESEVASEPGYQASVWVFCTISGLITLLPDGTIYGINHSFALMLFGYGKTELLGKNITCLIPGFYHCMDLAYDSSVQLPDLVNCLDIGSKSGPGEMSSDAKQDWELASGAQDPRID-VLTRGHMPSQDETLKLRGGQ-VSPRTQTQLETGRHILPSCASQPSLGVDSSPVDGERSLPTDQRNVPKRNLLAHAEQLLSQTQPDTLEISPPVLKE--LSEIQKNISEESPLTHRKWLLSKAQKDTTKGSLPIHDEKLLLASQHIHVLGKENPSAAESYREGLLAESRSKPVDAKPFASCEDSELLVPAKDRSNRADMSSLQQEAQLELMGISSPGSPNPWADATMPEPHTTGQIPGGS-LTYCPQHRSEWILQQRGQDSAPSPSAMGCVFVGTPTLDEPWPGVRNDREELQTCLIKEQLSKSSFGGALGISCVELVPAEHPPFTAPVSFCDWGGRDLHASRSGSSSACYALATDLPGVLEAVEAQEADVSSYSWNLRELFLNDRTDRTPSHCSCTTSELSETPSLSGVGSDLDVGILHRQTSDILAHREMLLLSGTYFDLREGHRFQEMGAGHDGAELSNISLVSSEHYETSDIESLGCDPPIPDPGPNNMCLSAEKPRLSAQITSTP--VAPGPTSLQQEIQEGIFSGSCYHRDGLRLSVQFEVKRVQLQGSATLFCCWLVKDFLHSHRDSATRTRLFLASLPSSTHS-MPDLSGSSFGEMLRAKPWFEESPTPAELEGLAACEGEYSHKYNTLRPLGSGAFGFVWTAVEKEGNKEVVVKFIKKEKVLEDCWVEDPKLGRVPLEISILSKVEHAN---IIKIVDVFENQGFFQLVMEKHGSG--LDLFAFIDRHPCLDEPLASYIFRQLVSAVRYLRSQGIIHRDIKDENIVIAEDFTIKLIDFGSAAYLEKGKLFYTFCGTIEYCAPEVLIGNPYRGPELEMWSLGVTLYTLIFEENPFCEVEETMEAVIHP--PFLVSQELMSLLSGLLQPCPEQRTTLEKLIVDPWVTQPVNLDNYTWEEVCRTSQPESGLMSAASLELASRSPSEVAQTEGLCRPPAPKEAPGN-HCLHLEDPSSPVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96RG2-1", "uniprot_id": "PASK_HUMAN", "id": "Q96RG2-1", "name": "PAS domain-containing serine/threonine-protein kinase", "aln": "MEDGGLTAFEEDQRCLSQSLPLPVSAEGPAAQTTAEPSRSFSSAHRHLSRRNGLSR-LCQSRTALSEDRWSSYCLSSLAAQNICTSKLHCPAAPEHTDPSE-PRGSVSCCSLLRGLSSGWSSPLLPAPVCNPNKAIFTVDAKTTEILVANDKACGLLGYSSQDLIGQKLTQFFLRSDSDVVEALSEEHMEADGHAAVVFGTV---------------------VDIISRSGEKIPVSVWMKRMRQERRLCCVVVLEPVERVSTWVAFQSDGTVTSCDSLFAHLHGYVSGEDVAGQHITDLIPSVQLPPSGQHIPKNLKIQRSVGRARDGTTFPLSLKLKSQPSSEEATTGEAAPVSGYRASVWVFCTISGLITLLPDGTIHGINHSFALTLFGYGKTELLGKNITFLIPGFYSYMDLAYNSSLQLPDLASCLDVGNESGCGERTLDPWQGQDPAEGGQDPRINVVLAGGHVVPRDEIRKLMESQDIFTGTQTELIAGGQLLSCLSPQPAPGVDNVPE---------------------------------------------------------------------------GSLPVHGEQALPKDQQITALGREEPVAIESPGQDLLGESRSEPVDVKPFASCEDSEAPVPAEDGGSDAGMCGLCQKAQLERMGVSGPSGSDLWAGAAVAKPQAKGQLAGGSLLMHCPCYGSEWGLWWRSQDLAPSPSGMAGLSFGTPTLDEPWLGVENDREELQTCLIKEQLSQLSLAGALDVPHAELVPTECQAVTAPVSSCDLGGRDLCGGCTGSSSACYALATDLPGGLEAVEAQEVDVNSFSWNLKELFFSDQTDQTSSNCSCATSELRETPSSLAVGSDPDVGSLQEQGSCVLDDRELLLLTGTCVDLGQGRRFRESCVGHDPTEPLEVCLVSSEHYAASDRESPGHVPSTLDAGPEDTCPSAEEPRLNVQVTSTPVIVMRGAAGLQREIQEGAYSGSCYHRDGLRLSIQFEVRRVELQGPTPLFCCWLVKDLLHSQRDSAARTRLFLASLPGSTHSTAAELTGPSLVEVLRARPWFEEPPKAVELEGLAACEGEYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSRVEHAN---IIKVLDIFENQGFFQLVMEKHGSG--LDLFAFIDRHPRLDEPLASYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNPYRGPELEMWSLGVTLYTLVFEENPFCELEETVEAAIHP--PYLVSKELMSLVSGLLQPVPERRTTLEKLVTDPWVTQPVNLADYTWEEVFRVNKPESGVLSAASLEMGNRSLSDVAQAQELCGGPVPGEAPNGQGCLHPGDPRLLTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08217-1", "uniprot_id": "PSK2_YEAST", "id": "Q08217-1", "name": "Serine/threonine-protein kinase PSK2", "aln": "------------------------------MTYPVSAAAPADISYSKNTPLVGLSKPPCLYQHASSSVDSFSSTFSDDDRSDLVAVPNESPHAFSYNPISPNSLGVRLTILRRSLEIMVNSPDILHELKKKAPVIAYPPSLRHTRNLTETATLSASRDPLNGSLISPLVSNMPSPASRPVIQRATSLMVLPDNDTASKLNPA----------------------------KSELENLLFLLNLALENNSFERASDLHMLSLLNIKKINFDSDIQKSETLKKVLLDSLAEPFFEN---YKKFPHKDLGSKSQYNEYEEKHDDIVSLADIKPQQDYSRILHPFTSAK--NSGPEAIFTCSQQYPWNFKAANDLACLTFG---ISKNVIKALTLLDLIHTDSRNFVLEKIMNAEDDNQEIVFTG--------ETIPIVQPNSTSNNNVPNLIWASLWAKRKNGLLVCVFEKTPCDYIDVMLNLRDFS------VDSIIDTTHFLENFDKKKQQ---------------------------------------------------------------------------------ESTSPMTEKKTVKFANEIHDIGSVSHSLSKLIDDVRFGKVFSADDDLLPLS--------IRVANHVNEERYFTLNCLSENIPCAVTTSVLENEIKLKIHSLPYQAGLFIVDS-------------------------HTLSLLSFNKSVAKNMFGLRLHELAGSSVTKLVPSLADMISYINKTYPMLNITLPENKGLVLTEHFFRKIEAEMHHDKDS-----FYTSIGLDGCHKDGNLIKVDVQLRVLNTNAVLLWITHSR-----DVVIENYTTVPSQLPMLKENEIDVVGSRGSSSASSK----------------KSSEKIPVNTLKAMADLSISSAETISNSDDE-------------------VDLNQVNEKLRETS----CGKVRGIESNDNNNYDDDMTMVDDPELKHKIELTKMYTQ-----------DKSKFVKDDNFKVDEKFIMRIIEPING--EEIKKETNELDKRNSTLKATYLTTPEANIGSQKRIKKFSDFTILQVMGEGAYGKVNLCIHNREHYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKNSQENILKLLDFFEDDDYYYIETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFGSAAYIKSG-PFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTIIYKENPYYNIDEILEGELRFDKSEHVSEECISLIKRILTREVDKRPTIDEIYEDKWLKI----------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: . . :: : . ***: * : * *. * :*. .:: : ... : .: . * * :* :. :. . : *. *. . . .. . . .**. :::: :. *:: :. : .*..:* :... .:: ::: .: :. . : : :: *. : ..::* * . : . . . :* :* . .*: . * : *. * . * *:. .*.. . * . : * * : ..* * . . * ** *:. :*: . : :: . ::.: . . : : .. .: . . :. : *: * :* . : ::* : .: *: :: : :.* :* . : : : : * * :: : . : . * :: .:: . : . * * : .* :. : ..... .: : :: .. : .*:. . ::. * .. . :: . . : : .* * : : :.**. * . ::: .: . . .: .** : .: ::. : : * : : * : ::.: *:* ** * .: : . :: .*. * . .. ::. :... *. .*. ::*: :: * .. . : *. . *: : . :. ::. : * . .. * : : . : .:. : :*.**:* * .:.:. : **:*:* **::* * *:.* *** :. ** *:: ::: . *:*::*.**:: :: : **. :*** .*: : : * *. :*:*:*::: :*: :.*:********::: .. :**********:: * * .* **::*.***** *..*:* ::*:*** ***::::***: :::* :*. :: . **:* :**:. :* ::*.*:::: * *:. ", "identical_positions": 172, "similar_positions": 384, "identity": "12.04%" }, { "cls_id": "homologset.agr.SGD:S000005409", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P46413-1", "uniprot_id": "GSHB_RAT", "id": "P46413-1", "name": "Glutathione synthetase", "aln": "MATSWG-SILQ-------DEKQLEELAQQAIDRALAEGVLLRSAKNPSSSDVVTYAPFTLFPSPVPSTLLEQAYAVQMDFNILVDAVSQNSAFLEQTLSST-----IKKDEYTARLFDIYKQVLKEG--IAQTVFLGLNRSDYMFQC------------------------------SADGSK---------------------------------------ALKQIEINTISASFGGLASRTPAVHRHVLNVLNKTNEASKILSNNPSKG-----LALGIAKAWELYGSAN-------AVVLLIAQEKERNIFDQRAIENELLDR--KIHVIRRRFEDVSERGSLDQNR-RLFMED--QEVAVVYFRDGYMPSQYNAQ-NWEARLLLERSCAAKCPDIATQLAGTKKVQQELSRVGLLEALLPGQPEAVARLRATFAGLYSLDMGEEGDQAVAEALAAPSHFVLKPQREGGGNNFYGEEMVHALEQLKDSEERASYILMEKIEPEPFRNCLLRPGS--PAQVVQCISELGIFGVYVRQGTTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51855-1", "uniprot_id": "GSHB_MOUSE", "id": "P51855-1", "name": "Glutathione synthetase", "aln": "MATSWG-SILQ-------DEKQLEELAKQAIDRALAEGVLLRSAQHPSSSDVVTYAPFTLFPSPVPSALLEQAYAVQMDFNILVDAVSQNPAFLEQTLSST-----IKKDDYTARLFDIYKQVLKEG--IAQTVFLGLNRSDYMFQC------------------------------GADGSK---------------------------------------ALKQIEINTISASFGGLASRTPAVHRHVLNVLNKTKEASKILSNNPSKG-----LALGIAKAWELYGSAN-------AVVLLIAQEKERNIFDQRAVENELLDR--KIHVIRGRFEDVSERGSLDQNR-RLFMDD--QEVAVVYFRDGYMPSQYNSQ-NWEARLMLERSRAAKCPDIAIQLAGTKKVQQELSRVGLLEALLPGQPEAVARLRATFAGLYSLDMGEEGDQAIAEALAAPSHFVLKPQREGGGNNLYGEEMVQALEQLKDSEERASYILMEKIEPEPFRNCLLRPGS--PAQVVQCISELGIFGVYVRQGTTLVMNKHVGHLLRTKAVEHADGGVAAGVAVLDNPYPV---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48637-1", "uniprot_id": "GSHB_HUMAN", "id": "P48637-1", "name": "Glutathione synthetase", "aln": "MATNWG-SLLQ-------DKQQLEELARQAVDRALAEGVLLRTSQEPTSSEVVSYAPFTLFPSLVPSALLEQAYAVQMDFNLLVDAVSQNAAFLEQTLSST-----IKQDDFTARLFDIHKQVLKEG--IAQTVFLGLNRSDYMFQR------------------------------SADGSP---------------------------------------ALKQIEINTISASFGGLASRTPAVHRHVLSVLSKTKEAGKILSNNPSKG-----LALGIAKAWELYGSPN-------ALVLLIAQEKERNIFDQRAIENELLAR--NIHVIRRTFEDISEKGSLDQDR-RLFVDG--QEIAVVYFRDGYMPRQYSLQ-NWEARLLLERSHAAKCPDIATQLAGTKKVQQELSRPGMLEMLLPGQPEAVARLRATFAGLYSLDVGEEGDQAIAEALAAPSRFVLKPQREGGGNNLYGEEMVQALKQLKDSEERASYILMEKIEPEPFENCLLRPGS--PARVVQCISELGIFGVYVRQEKTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86B44-1", "uniprot_id": "Q86B44_DROME", "id": "Q86B44-1", "name": "Glutathione synthetase", "aln": "MSSDANTAVLRNCIRLPLAEDELLEVTAKAKDYAIMHGAAMRS-KTAFSPDSLNFAPFVLVPSSFPRKEFEKAVALQPIINRLMHNVAHDEEFITTTLAET-----IKVDEFTANLFNIYRKVLAHG--FTQKTSLGMLRSDLMLESGCPELSPRALRTAAGEDRGQDAGAAVGQIAGANGAAGVGTAAGTGSKEEEHREVQLSRVTKEPERRATGAQSAYCCWKQVEINTIASGFGHLGPASKTIQRFVLSELGHADKLHNMPDNNALAG-----LCDGMVKAWDIYAKPQ-------AVILFIIEDVSYNICDQRFHEFYIRETYPHIKVLRRTLTEVHREGKLGQSK-ELLLGS--QEVAVIYFRAGYEPGHYHSQADWDARYLMETSLAIKCPSIHYHLAGTKKVQQALAQPAVLERFIN-DPEEIKAVGKIFTGLYSLDDNEAGNASYEMALRTPERFVLKPQREGGGNNVYGVDIPDALKRMS-RVERSAWILMDLIHPPLTKGYMVRPGGDMPPQIVDMVSELGIFGVVIGDAEHIVHNYQAGHMLRTKLSTANEGGVAAGLGALDSPYLIDSDDEDEQK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08220-1", "uniprot_id": "GSHB_YEAST", "id": "Q08220-1", "name": "Glutathione synthetase GSH2", "aln": "MAHYPP------------SKDQLNELIQEVNQWAITNGLSMYPPKFEENPSNASVSPVTIYPTPIPRKCFDEAVQIQPVFNELYARITQDMAQPDSYLHKTTEALALSDSEFTGKLWSLYLATLKSAQYKKQNFRLGIFRSDYLIDK-------------------------------KKGTE---------------------------------------QIKQVEFNTVSVSFAGLSEKVDRLHSYLNRANKYDPKGPIYNDQNMVISDSGYLLSKALAKAVESYKSQQSSSTTSDPIVAFIVQRNERNVFDQKVLELNLLEK-FGTKSVRLTFDDVNDKLFIDDKTGKLFIRDTEQEIAVVYYRTGYTTTDYTSEKDWEARLFLEKSFAIKAPDLLTQLSGSKKIQQLLTDEGVLGKYIS-DAEKKSSLLKTFVKIYPLDDTKLGREGKRLALSEPSKYVLKPQREGGGNNVYKENIPNFLKGIEERHWDA-YILMELIEPELNENNIILRDN--KSYNEPIISELGIYGCVLFNDEQVLSNEFSGSLLRSKFNTSNEGGVAAGFGCLDSIILY---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :.:* *: :. : *: .* : . : ... . :*..: *: .* :::* :* :* * :::: * .* :. .::*..*:.:: .* . *. **: *** ::: .*: **:*:**:: .*. *. :: .: : .:* . *. .:.** : * . : .:: :* : . *: **: * : : :* : :: . :.:. .*:: . **:**:*:* ** . .* : :*:** ::* * * *.*.: :*:*:**:** *: .:* : :.* : *. :*.** : * . ** *.::************.* :: . *: :. : :***: *.* .. :: .. . :*****:* : : :: * * :**:* :******.. **. ", "identical_positions": 115, "similar_positions": 160, "identity": "19.59%" }, { "cls_id": "homologset.agr.SGD:S000005412", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z6H8-1", "uniprot_id": "DCAM2_MOUSE", "id": "D3Z6H8-1", "name": "S-adenosylmethionine decarboxylase proenzyme 2", "aln": "---------------------MEAAHFFEGTEKLLEVWFSRQQSDASQGSGDLRTIPRSEWDVLLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQS---------FFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMN-SDCWYLYTLDFP-----------ESRVISQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRES-----------------------GIRDLIPGSVIDATLFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYD-------HLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLSSPQKIDG----FKRLDCQSAMFNDYNFVFTSFAKKQQQQQS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DMN7-1", "uniprot_id": "DCAM1_MOUSE", "id": "P0DMN7-1", "name": "S-adenosylmethionine decarboxylase proenzyme 1", "aln": "---------------------MEAAHFFEGTEKLLEVWFSRQQSDASQGSGDLRTIPRSEWDVLLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQS---------FFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMN-SDCWYLYTLDFP-----------ESRVISQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRES-----------------------GIRDLIPGSVIDATLFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYD-------DLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLSSPQKIDG----FKRLDCQSAMFNDYNFVFTSFAKKQQQQQS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17708-1", "uniprot_id": "DCAM_RAT", "id": "P17708-1", "name": "S-adenosylmethionine decarboxylase proenzyme", "aln": "---------------------MEAAHFFEGTEKLLEVWFSRQQSDASQGSGDLRTIPRSEWDVLLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQS---------FFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMN-SDCWYLYTLDLP-----------ESRVINQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRES-----------------------GIRDLIPGSVIDATLFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYD-------DLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLSSPQKIDG----FKRLDCQSAMFNDYNFVFTSFAKKQQQQS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P17707-1", "uniprot_id": "DCAM_HUMAN", "id": "P17707-1", "name": "S-adenosylmethionine decarboxylase proenzyme", "aln": "---------------------MEAAHFFEGTEKLLEVWFSRQQPDANQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQS---------FFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMN-SDCWYLYTLDFP-----------ESRVISQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRES-----------------------GIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYD-------DLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLASPQKIEG----FKRLDCQSAMFNDYNFVFTSFAKKQQQQQS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P91931-1", "uniprot_id": "DCAM_DROME", "id": "P91931-1", "name": "S-adenosylmethionine decarboxylase proenzyme", "aln": "-------------------MLENGSHFFEGVEKLLEIWFE----ESSNGDDDLRNISRSDWENVLSNVNCQIISTSKNDIIDAFVLSESSMFVSKRRWILKTCGTTTPLKCLGQLLKLAEAN-GYNVVAD---------LFYSRKNFTRPEAQITPHQGFTEEVTYLDSIFPNGRSYCLGSMN-LECWYLYTFSRSDIKITPQLISDEKNVDSDPDQTIEILMQDLDPETMSIFYKNKFNDANGATVKS-----------------------GIDTILPTMHIDDFLFDPCGYSMNGINDKGEYMTIHITPENQFSYVSFETNVALSNYR-------KLINQVINTFKPGKFIVTIFANKCSLAYETMKELEVEYSQGSHWKRTDMQCCNFPSYNLLFAQYSHSEKTGDNL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21182-1", "uniprot_id": "DCAM_YEAST", "id": "P21182-1", "name": "S-adenosylmethionine decarboxylase proenzyme", "aln": "MTVTIKELTNHNYIDHELSATLDSTDAFEGPEKLLEIWFFPHKKSITT-EKTLRNIGMDRWIEILKLVKCEVLSMKKTKELDAFLLSESSLFVFDHKLTMKTCGTTTTLFCLEKLFQIVEQELSWAFRTTQGGKYKPFKVFYSRRCFLFPCKQAAIHQNWADEVDYLNKFFDNGKSYSVGRNDKSNHWNLYVTETDRSTPK------GKEYIEDDDETFEVLMTELDPECASKFVCGPEASTTALVEPNEDKGHNLGYQMTKNTRLDEIYVNSAQDSDLSFHHDAFAFTPCGYSSNMILAEKYYYTLHVTPEKGWSYASFESNIPVFDISQGKQDNLDVLLHILNVFQPREFSMTFFTKNYQ--NQSFQKLLSINESLPDYIKLDKIVYDLDDYHLFYMKLQKKI------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:. *** *****:** . . . **.* . * :*. *:*.::* .*.. :*::*****:** .:: :****** * .* *:::.. .: .****: * * * *:.: :*: :*: :* ** :*.:* : : * **. . .. .: *:*:*:** :*** . * :. . . . * * ***** * : . * *:*:*** :**.***:*:. . .:: ::::.*:* :* *:*.:: . : . : : * : .*::.: . :. ", "identical_positions": 90, "similar_positions": 104, "identity": "21.9%" }, { "cls_id": "homologset.agr.SGD:S000005417", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15327-1", "uniprot_id": "PMGE_MOUSE", "id": "P15327-1", "name": "Bisphosphoglycerate mutase", "aln": "---MSKHKLIILRHGEGQWNKENRFCSWVDQKLNNDGLEEARNCGRQLKALN-----FEFDLVFTSILNRSIHTAWLILEELG-----------------------QEWVPVESSWRLNERHYGALIGLNREKMALNHGEEQVRLWRRSYNVTPPPIEESHPYFHEIYSDR--------------RYKVCDVPLDQLPRSESLKDVLERLLPYWKERIAP--EILKGKSILISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGNQEAIQAAIKKVDDQGKVKQGKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07738-1", "uniprot_id": "PMGE_HUMAN", "id": "P07738-1", "name": "Bisphosphoglycerate mutase", "aln": "---MSKYKLIMLRHGEGAWNKENRFCSWVDQKLNSEGMEEARNCGKQLKALN-----FEFDLVFTSVLNRSIHTAWLILEELG-----------------------QEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRSYNVTPPPIEESHPYYQEIYNDR--------------RYKVCDVPLDQLPRSESLKDVLERLLPYWNERIAP--EVLRGKTILISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEAIQAAIKKVEDQGKVKQAKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12326-1", "uniprot_id": "PMG3_YEAST", "id": "Q12326-1", "name": "Phosphoglycerate mutase 3", "aln": "MTVTDTFKLFILRHGQSELNSENIFCGWIDAQLTEKGKSQARHSAKLIKQFCDSNNISLPQIGYTSRLIRTQQTMDVILEELGLKHTNYVITTNTNIKEELQDTRFEGSMPVLQTWRLNERHYGAWQGQRKPDILKEYGKEKYMYIRRDYNGKPPKVNLNLEMVQEENDQGSSTGYDFKEPNRHLKYGPEEKANERLPESESLCEVVVRLKPFLNNVVLSTANKISQESCVIVGHGSSVRSLLKVLEGISDEDIKDVDIPNGIPLVIELDRDNYSFVRKFYLD-PESAKVNAQMVRDEGFEKNP--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ...**::****:. *.** **.*:* :*...* .:**:..: :* : :: :** * *: :* :****** : :** .:********** * .: .: ::*:*: **.** .** :: . :* .: :* : . ::**.**** :*: ** *: :: : . : : :: :* .**.* *:*** ********* :: :*.*:*:::***.: :. : :*. *: :. : * *:* *: ", "identical_positions": 91, "similar_positions": 90, "identity": "29.74%" }, { "cls_id": "homologset.agr.SGD:S000005418", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55096-1", "uniprot_id": "DPP3_RAT", "id": "O55096-1", "name": "Dipeptidyl peptidase 3", "aln": "---------------------------------------------------------------MADT--QYILPNDIGVSSLDCR-EAFRLLSPTERLYAHHLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKEKLERVILGSKAAQQ----------------HPEEVRSLWQTCGELMFSLEPRLRHLGLGKEGVTTYFSG--DCAMEDAKLAQDFLDSQNLSAYNTRLFKVVGQEGKYHYEVRLASVLNTEPALDSELTSKLKSYEFQGNHFQVTRGDYAPILQKVVEHLEKAKAYAANSHQEQMLAQYVESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAMVNKDMSAKFERLVASAEQLLKELPWPPAFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAY-ATKREKLTFMEEEDKDLYIRWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDQETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLNPQVLQIFGFEG-TDAEDVIYVNWLNMVRAGL-LALEFYTPETANWRQAHMQARFVILRVLLEAGEGLVTVTPTTGSDGRPDARVHLDRSKIRSVGKPALERFLRRLQVLKSTGDVVAGRALYEGYAAVTDAPPECFLTLRDTVLLRKESRKLIVQPNTRLE-GSEVQLVEYEASAAGLIRSFCERFPEDGPELEEVLTQLATADAQFWRDQVQEAPSGQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99KK7-1", "uniprot_id": "DPP3_MOUSE", "id": "Q99KK7-1", "name": "Dipeptidyl peptidase 3", "aln": "---------------------------------------------------------------MADT--QYILPNDIGVSSLDCR-EAFRLLSPTERLYAHHLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKDKLGRVILGSKAAQQ----------------RPEEVRDLWQTCGDLMFSLEPRLRHLGLGKEGVTTYFSG--DCTMEDAKLAQDFLDSQNLSAYNTRLFKVVGQEGKSHYEVRLASVLNTDPALDSELTSKLKRYEFQGNHFQVTRGDYAPILQKVVEHLEKAKAYAANSHQEQMLAQYVESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAMVNKAMSAKFERLVASAEQLLKELPWPLAFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAY-AAKREKLTFLEEEDKDLYIRWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDKETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLNPQVLEIFGFEG-ADAEDVIYVNWLNMVRAGL-LALEFYTPEAANWRQAHMQARFVILRVLLEAGEGLVTVTPTTGSDGRPDARVRLDRSKIRSVGRPALERFLRRLQVLKSTGDVVAGRALYEGYAAVTDAPPECFLTLRDTVLLRKESRKLIVQPNTRLE-GSEVQLVEYEASAAGLIRSFCERFPEDGPELEEVLIQLAAADARFWRNQAQEAPPGQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NY33-1", "uniprot_id": "DPP3_HUMAN", "id": "Q9NY33-1", "name": "Dipeptidyl peptidase 3", "aln": "---------------------------------------------------------------MADT--QYILPNDIGVSSLDCR-EAFRLLSPTERLYAYHLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKEKLERVILGSEAAQQ----------------HPEEVRGLWQTCGELMFSLEPRLRHLGLGKEGITTYFSG--NCTMEDAKLAQDFLDSQNLSAYNTRLFKEVDGEGKPYYEVRLASVLGSEPSLDSEVTSKLKSYEFRGSPFQVTRGDYAPILQKVVEQLEKAKAYAANSHQGQMLAQYIESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAVVNKAMSAKFERLVASAEQLLKELPWPPTFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAY-ATQREKLTFLEEDDKDLYILWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDQETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLHPQVLEIFGFEG-ADAEDVIYVNWLNMVRAGL-LALEFYTPEAFNWRQAHMQARFVILRVLLEAGEGLVTITPTTGSDGRPDARVRLDRSKIRSVGKPALERFLRRLQVLKSTGDVAGGRALYEGYATVTDAPPECFLTLRDTVLLRKESRKLIVQPNTRLE-GSDVQLLEYEASAAGLIRSFSERFPEDGPELEEILTQLATADARFWK-GPSEAPSGQA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHR8-1", "uniprot_id": "DPP3_DROME", "id": "Q9VHR8-1", "name": "Dipeptidyl peptidase 3", "aln": "MFWLRGLQRSRQQLNRLCHFRSRLNYGTSPSIRSVQPSISRSLGFCSSLVRYSCSTNLPQPAEMASKTAHFVLPNTQPIADLDCK-SAFENLTEKEKLYAHHFSQASWDGGLIALIQSSPEAPLIFSLLHRIFLAEKIPVLRAKALEAGVSADDFTAFLVYACGVFANAGNYKGMGDSKIVPNLSEKQFETIVKASAAYSD----------------EPR-VGKIFEKVKNLIYALESRNEILGFAPDGITTYWSD--NCTKEDSEIVNAWLTSKRIEPYMCRTFKIVEN-GQTVYDVKLGSVAES-----TQDGITLPLEEYNGNKFRVTRGDYQKLLQRVNQHLLQAQKYAANENESKMIEHYVRSFEQGSLDEHKNGSRWWIKDKGPVIETYIGFIETYRDPAGGRAEFEGFVAMVNKESSAKFSELVNRAEKLIEYLPWTEPYEKDSYLKPDFTSLDVLTFAGSGVPAGINIPNYDEIRQDEGFKNVSLGNVLAN---INRKDPIPFLTEEDQTLMKEYKVKAFEVQVGLHELLGHGSGKLFRIDENGVYNFDKENTKNLVTGEPITKWYLPGETYDTKFGAIGSSYEECRAEAVGLYLSLQRDILEIFGFKDKAEQDNIIYVNWLSLIWNGMGVALEMFNPKSKLWLQAHSRARFVIMKVLLEAGEGLVKVEETE--KGK-NLLLTVDRSKIDTVGRKALGDFLTKLQVYKSTADIEAASKMYEHYSKVDESGSHPWAKWRDICLAHKKPRMILVQANTAIGQDQKVQLKTYEPTHEGYIQSWVERYPN--TDIDDLLESIVEKDKKYFPTAFNN------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08225-1", "uniprot_id": "DPP3_YEAST", "id": "Q08225-1", "name": "Probable dipeptidyl peptidase 3", "aln": "-------------------------------------------------------------------MSHFFADHDAPLSMLSVKTEYFPQLTDKEQKYAHFMSKASHAGSRVVMRQVSHESEPIFDLILAIHSKLN----GKYPEDDITQKQQTGLYLEYVSQFLSNLGNFKSFGDTKFIPRCEVKFFKQLLELAKINPCSSPLTLSPVDVNHEFTSHHLFSTINELIDIGIYHVEEKAALLGFPSQGYTSAYYLGLPVTPEDMALLKEQLFAELAILPEN---TRINKVGENSFQIWVASENVKNQITETYPSGQITLSN-AVTKVEFIFGDHSREMRLVASYLKEAQKFAANDTQKAMLQEYINHFVTGSSQAHKEAQKLWVKDISPVIETNIGFIETYREPSGIIGEFESLVAIQNKERTAKFSSLVNNAEEFISLLPWSKDYEKPIFNPPDFTSLEVLTFTGSGIPAGINIPNYDDVRLKIGFKNVSLGNILSAAAKSSSKHPPSFISQEDRPIFEKYQSDSFEVQVGIHELLGHGSGKLLTEFTDG-FNFDKENPPLGLDGKPVSTYYKVGETWGSKFGQLAGPFEECRAEVIAMFLLTNKKILDIFGFHDVESQDKVIYAGYLQMARAGL-LALEYWNPKTGKWGQPHMQARFSIMKTFMKHSTDKNFLKLEMN-STNDDFAIKLDKSLIKTAGHECVKDYLKHLHVYKCSGDVEQGSKYFIDRSTVTP----DLASLRDIVLSKRLPRRQFIQSNSYIDDNNKVTLKEYDETPQGMLQSFLDREL---------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. : :: *. : . * *: .*: **:.:*:*: *. .: * * *: *: *: :. . . :: :* *.. . :* **:*.:**:*::*. . : :: : . . : : :: :* : **: :* *: : : ** : : * :: . : *: ::: :.* . : : : . ... **: :: * . * :*: :***. : *: .*:. * ** : **...: *::* .*::*: *****:**:* * .***.:**: ** :***. ** **:::. ***. :** : ******:****:***:**********::* *********:*: :. .*: ::*: : :: :*:****:***********: .* :***:*. *: : .:* ***:.:**. :...:****** :.::* : .:*:****.. . :.:**..:*.: *: :*** :.*:: * *.* :*** *::.::: . . : . . : : :*:* * :.*: .: :* :*:* *.:.*: . : : * . ** * :: .* ::*.*: : ...* * *: : * ::*: :* ", "identical_positions": 194, "similar_positions": 231, "identity": "23.49%" }, { "cls_id": "homologset.agr.SGD:S000005419", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09034-1", "uniprot_id": "ASSY_RAT", "id": "P09034-1", "name": "Argininosuccinate synthase", "aln": "MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVFIEDVSKEFVEEFIWPAVQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATGKGNDQVRFELTCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKSPWSMDENLMHISYEAGILENPKNQAPPGLYTKTQDPA-KAPNTPDVLEIEFKKGVPVKVTNVKDGT----THSTSLDLFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAFTMDREVRKIKQGLG-LKFAELVYTGFWHSPECEFVRHCIDKSQERVEGKVQVSVFKGQVYILGRESPL---SLYNEELVSMNVQGDYEPIDATGFININSLRLKEYHRLQSK--VTAK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16460-1", "uniprot_id": "ASSY_MOUSE", "id": "P16460-1", "name": "Argininosuccinate synthase", "aln": "MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVFIEDVSKEFVEEFIWPAVQSSALYEDRYLLGTSLARPCIARRQVEIAQREGAKYVSHGATGKGNDQVRFELTCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKSPWSMDENLMHISYEAGILENPKNQAPPGLYTKTQDPA-KAPNSPDVLEIEFKKGVPVKVTNIKDGT----TRTTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAFTMDREVRKIKQGLG-LKFAELVYTGFWHSPECEFVRHCIQKSQERVEGKVQVSVFKGQVYILGRESPL---SLYNEELVSMNVQGDYEPIDATGFININSLRLKEYHRLQSK--VTAK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00966-1", "uniprot_id": "ASSY_HUMAN", "id": "P00966-1", "name": "Argininosuccinate synthase", "aln": "MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVFIEDVSREFVEEFIWPAIQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATGKGNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWSMDENLMHISYEAGILENPKNQAPPGLYTKTQDPA-KAPNTPDILEIEFKKGVPVKVTNVKDGT----THQTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAFTMDREVRKIKQGLG-LKFAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVLKGQVYILGRESPL---SLYNEELVSMNVQGDYEPTDATGFININSLRLKEYHRLQSK--VTAK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66I24-1", "uniprot_id": "ASSY_DANRE", "id": "Q66I24-1", "name": "Argininosuccinate synthase", "aln": "-MSKGLVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQDEDFDVARKKAEKLGAKKVFIEDLRSEFVQEFIWPALQANALYEDRYLLGTSIARPCIARRQVQIAQREGAQYVSHGATGKGNDQVRFELTCYALYPQVQVIAPWRIPEFYNRFRGRKDLMEYAEKHNIPVPVTPKAPWSMDANLMHISYESGILENPKNHAPSDLYQMTKNPE-HSPDQADMLEIEFKKGVPVRVSHLKDGI----SKETPLEIFCYLNEIGGKHGVGRIDIVENRFIGMKSRGIYETPGGTVLLQAHLDIETFTMDREVRKIKQSLG-IKFSELIYNGFWFSPECEFVRECVERSQKHVEGRVQLSVYKGQVYILGRESPK---SLYNEELVSMDVQGDYDPCDASGFIKINAVRLREHNRLQGA--ALSKHNV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O97069-1", "uniprot_id": "ASSY_DROME", "id": "O97069-1", "name": "Argininosuccinate synthase", "aln": "-MPKETVILAYSGGLDTSCVLKWLLDKQYEVICVLADVGQKEDFTAAEKKALKIGAKKVIVADVKQSFVEDYIWPAVQMGLVYEERYLLGTSLARPCISVALMEVAREYGAKYLAHGATGKGNDQVRFELCAYALKPDLKIIAPWRDVEFCCQFQGRQDLIAYAQQHGIEVSAKPATPWSTDANILHISYESGILEDPNTVAPENLYEMTVDPLTRAPRDPVHLVIQFDRGLPSSVEDLPGGR----VYTKPLEMLDFLNKLGGSYGIGRIDIVENRFVGLKSRGVYETPGGTILFAAHQDLEVFALDREVLRTKQVLR-DRMADYVYNGFWFSPEAIYARKCIELAEQRVSGKVTVELAPGYCRAIARKAAKDVGALYNEQLVSMDVHGGYVPQDAGGFIAINAVRIREHVRAFGAYDVPTKKN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22768-1", "uniprot_id": "ASSY_YEAST", "id": "P22768-1", "name": "Argininosuccinate synthase", "aln": "-MSKGKVCLAYSGGLDTSVILAWLLDQGYEVVAFMANVGQEEDFDAAKEKALKIGACKFVCVDCREDFVKDILFPAVQVNAVYEDVYLLGTSLARPVIAKAQIDVAKQEGCFAVSHGCTGKGNDQIRFELSFYALKPDVKCITPWRMPEFFERFAGRKDLLDYAAQKGIPVAQTKAKPWSTDENQAHISYEAGILEDPDTTPPKDMWKLIVDPM-DAPDQPQDLTIDFERGLPVKLTYTDNKTSKEVSVTKPLDVFLAASNLARANGVGRIDIVEDRYINLKSRGCYEQAPLTVLRKAHVDLEGLTLDKEVRQLRDSFVTPNYSRLIYNGSYFTPECEYIRSMIQPSQNSVNGTVRVRLYKGNVIILGRSTKT--EKLYDPTESSMDELTGFLPTDTTGFIAIQAIRIKKYGESKKTKGEELTL--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* * ********** :* ** :: *:*:. :*::**.*** *.:** *:** *.. * .**:: ::**:* . :**: ******:*** *: :::*:. *. ::**.*******:**** *:* *::: *:*** ** :* **:**: ** ::.* :. . *** * * *****:****:*.. .* .:: :* :* . * *:*.:*:* : . ..*::: .::. *:*******:*::.:**** ** . *:* ** *:* :::*:** : :: : . : :*.* :.:**. : * : ::: *.* * : : * :.*.: **: **: .: * *: *** *:::*:::: . . ", "identical_positions": 149, "similar_positions": 128, "identity": "34.98%" }, { "cls_id": "homologset.agr.SGD:S000005420", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35077-1", "uniprot_id": "GPDA_RAT", "id": "O35077-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic", "aln": "--------------------------------------------------------------------------------MAGKKVCIVGSGNWGSAIAKIVGSNASQL-AHFDPRVTMWVFEEDIGGRKLTEIINTQHENVKYLPGHKLPPNVVAVPDVVQAATGADILVFVVPHQFIGKICDQLKGHLKANTIGISLIKGIDEGPNG-LKLISEVIGESLGIPMSVLMGANIASEVAEEKFCETTIGCKDPAQG---------QLLKELMQTPNFRITVVQEVDTVEICGALKNIVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAKLFCSGS-VSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKEMLNGQKLQGPQTARELHSILQHKGLVDKFPLFTAVYKVCYEGQPVGEFICCLQNHPEHM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13707-1", "uniprot_id": "GPDA_MOUSE", "id": "P13707-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic", "aln": "--------------------------------------------------------------------------------MAGKKVCIVGSGNWGSAIAKIVGSNAGRL-AHFDPRVTMWVFEEDIGGRKLTEIINTQHENVKYLPGHKLPPNVVAIPDVVQAATGADILVFVVPHQFIGKICDQLKGHLKANTIGISLIKGVDEGPNG-LKLISEVIGERLGIPMSVLMGANIASEVAEEKFCETTIGCKDPAQG---------QLLKDLMQTPNFRITVVQEVDTVEICGALKNIVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAKLFCSGT-VSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKEMLNGQKLQGPQTARELHSILQHKGLVDKFPLFTAVYKVCYEGQPVGEFIRCLQNHPEHM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21695-1", "uniprot_id": "GPDA_HUMAN", "id": "P21695-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic", "aln": "--------------------------------------------------------------------------------MASKKVCIVGSGNWGSAIAKIVGGNAAQL-AQFDPRVTMWVFEEDIGGKKLTEIINTQHENVKYLPGHKLPPNVVAVPDVVQAAEDADILIFVVPHQFIGKICDQLKGHLKANATGISLIKGVDEGPNG-LKLISEVIGERLGIPMSVLMGANIASEVADEKFCETTIGCKDPAQG---------QLLKELMQTPNFRITVVQEVDTVEICGALKNVVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAKLFCSGP-VSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKELLNGQKLQGPETARELYSILQHKGLVDKFPLFMAVYKVCYEGQPVGEFIHCLQNHPEHM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3ULJ0-1", "uniprot_id": "GPD1L_MOUSE", "id": "Q3ULJ0-1", "name": "Glycerol-3-phosphate dehydrogenase 1-like protein", "aln": "------------------------------------------------------------------------------MAAAPLKVCIVGSGNWGSAVAKIIGSNVKTL-QKFSSTVKMWVFEETVNGRKLTDIINNDHENVKYLPGHKLPENVVAVPNLSEAVQDADLLVFVIPHQFIHKICDEITGRVPEKALGITLIKGIDEGPDG-LKLISDIIREKMGIDISVLMGANIASEVAAEKFCETTIGSKVMQNG---------LLFKELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAFAKIFCKGQ-VSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKELLNGQKLQGPQTSAEVYRILRQKGLLDKFPLFTAVYQICYEGRPVTQMLSCLQSHPEHI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZAP9-1", "uniprot_id": "D3ZAP9_RAT", "id": "D3ZAP9-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "aln": "------------------------------------------------------------------------------MAAAPLKVCIVGSGNWGSAVAKIIGSNVKNL-QKFSSTVKMWVFEETVNGRKLTDIINNDHENVKYLPGHKLPENVVAVPNLGEAVQDADLLVFVIPHQFIHKICDEITGRVPKKAVGITLIKGIDEGPDG-LKLISDIIREKMGIDISVLMGANIASEVAAEKFCETTIGSKVLQNG---------LLFKELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLCCGDNTKAAVIRLGLMEMIAFAKIFCKGQ-VSTATFLESCGVADLITTCYGGRNRKVAEAFARTGKTIEELEKELLNGQKLQGPQTSAEVYRILKQKGLLDKFPLFTAVYQICYEGRPVTQMLSCLQSHPEHI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N335-1", "uniprot_id": "GPD1L_HUMAN", "id": "Q8N335-1", "name": "Glycerol-3-phosphate dehydrogenase 1-like protein", "aln": "------------------------------------------------------------------------------MAAAPLKVCIVGSGNWGSAVAKIIGNNVKKL-QKFASTVKMWVFEETVNGRKLTDIINNDHENVKYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITLIKGIDEGPEG-LKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENG---------LLFKELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAFARIFCKGQ-VSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKEMLNGQKLQGPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEMLSCLQSHPEHT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZKP8-1", "uniprot_id": "A0A8I5ZKP8_RAT", "id": "A0A8I5ZKP8-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "aln": "------------------------------------------------------------------------------MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQ-QKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRG-LMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNG---------ILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQ-VSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6ALX9-1", "uniprot_id": "A0A8I6ALX9_RAT", "id": "A0A8I6ALX9-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "aln": "-----------------------------MTHYTRVVNVFFKQVGRQAGQGTSRLDQIDGGQQLAEKAPSPQQDIGLKVLPGPLKVSIVGSGNWASAVSKIIGNNVKTT-KKFASPVKMWVFEEIVNGRKLTDIINTDHENVKYLPGYRLPENVIATPSLSQAVQDADLLVFAFPHQFIRKICDELAEVVPRKARGLTLIKGIDEGPES-LKLISDIIREKVNIDVSVLMGANLANEVAAEQFCETTIGSKVLQNG---------LLFKELFQTPNFRVTVVEDPDTVELCGALKNIVAMGSGFCDSFCCGNSTKAAVIRLGLMEMISFVRTFSKGQ-VSIATFLESCGVADLISTCYGGRNRKVAEAFARTGKSLEELEKEMLKGQKLQGPHTSAQVYRILKQKGLLDKFPLFTVVYQICYEGRAVTELIPCLQNHPEHRRRELGTSPALPHPSQGHTDTRT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5XIZ6-1", "uniprot_id": "GPD1L_DANRE", "id": "Q5XIZ6-1", "name": "Glycerol-3-phosphate dehydrogenase 1-like protein", "aln": "-------------------------------------------------------------------------------MAAPLKVCIVGSGNWGSAIARIIGSNAQKL-QCFATTVKMWVYEEMVNGKKLSEIINTEHENVKYLPGYKLPENVVAVPQLRDAADGADLLVFVVPHQFIRKLCDEMMGCVSERARGITLIKGIDEGPEG-LKLISDIIREKMGIDVSVLMGANIANEVAAEKFCESTIGSKVLENG---------LLFKDLLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLQCGDNTKAAVIRLGLMEMIAFAKLFSKDDSVSSATFLESCGVADLITTCYGGRNRRVAEAFAKTGKSIEELEKEMLNGQKLQGPLTSAEVYHILKQKGLVEKFPLFTAVYQICFEDKPVRDMITCLQSHPEHL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13706-3", "uniprot_id": "GPDA_DROME", "id": "P13706-3", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic", "aln": "-------------------------------------------------------------------------------MADKVNVCIVGSGNWGSAIAKIVGANAAAL-PEFEERVTMFVYEELIDGKKLTEIINETHENVKYLKGHKLPPNVVAVPDLVEAAKNADILIFVVPHQFIPNFCKQLLGKIKPNAIAISLIKGFDKAEGGGIDLISHIITRHLKIPCAVLMGANLANEVAEGNFCETTIGCTDKKYG---------KVLRDLFQANHFRVVVVDDADAVEVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDVFYPGS--KLSTFFESCGVADLITTCYGGRNRRVSEAFVTSGKTIEELEKEMLNGQKLQGPPTAEEVNYMLKNKGLEDKFPLFTAIHKICTNQLKPNDLIDCIRNHPEHMDTSIMPSPKL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41911-1", "uniprot_id": "GPD2_YEAST", "id": "P41911-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)] 2, mitochondrial", "aln": "MLAVRRLTRYTFLKRTHPVLYTRRAYKILPSRSTFLRRSLLQTQLHSKMTAHTNIKQHKHCHEDHPIRRSDSAVSIVHLKRAPFKVTVIGSGNWGTTIAKVIAENTELHSHIFEPEVRMWVFDEKIGDENLTDIINTRHQNVKYLPNIDLPHNLVADPDLLHSIKGADILVFNIPHQFLPNIVKQLQGHVAPHVRAISCLKGFELGSKG-VQLLSSYVTDELGIQCGALSGANLAPEVAKEHWSETTVAYQLPKDYQGDGKDVDHKILKLLFHRPYFHVNVIDDVAGISIAGALKNVVALACGFVEGMGWGNNASAAIQRLGLGEIIKFGRMFFPES-KVETYYQESAGVADLITTCSGGRNVKVATYMAKTGKSALEAEKELLNGQSAQGIITCREVHEWLQTCELTQEFPLFEAVYQIVYNNVRMEDLPEMIEELDIDDE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8IN06-1", "uniprot_id": "Q8IN06_DROME", "id": "Q8IN06-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "aln": "-------------------------------------------------------------------------------MAGKLKICIIGAEGWGSAIAAVVSNNVLEG--DFDSRVHLYVYDEMIRDTALSEIINTRHENVKYLPGIKLPNNLIAVNDLLEAAQNADILVFSTPLEFVQSYCNILSGNVKESAFAVSMTKGLLSENGEGIELVSHAISESLGIPCYSMMSAHSAMEMAQGKLCEVTIGCSDNSHS---------KLLISAMQTNNCRVISVNDVDGVELCGTLTDVVALGAGFIDGLRLGENARLAAIHLGVKEIMRFIKTFFPSS--KMSTFYESCGVTNAVASSFVDKNVTFAKSLVTSGQTIEEIEANLHSGRKLLGPMVASNVNAFLENGLMQHEFPLFTAIHLICQSEAPPELMIEALRNHPDLSSSSISHLLNHERDELKTDQGLPELRTALDKILTEAGNENIKQLKVMDDWTEVNDYDVEETYHEKVASRDSCLETEIMPSRLSVQAAQLYNDIRDGNVGVAFKMDIDEGNRQVRLLLEKEDEMASDAALTVISSRLTAGQEDDNARIGHGHITNTSAESDHMSSKSIPSGLTTKDSPDVLDLSCESEPLHSSKQNSQLMEDAETNFTERLKVNQLKEQIDKQEAANFKAQENLIKSIRQTIQALGDKEKMENLIAKSKMEEDPFQLKSQVESSQLKSQVEGESSELKNQIQEEAYEPISQADEEPSQIRSQLDEESAQLKSLMDEENRQLESEMQDESSLLKSSADKSEFVAYNAEEEQPIEEPTDNHQYKLRSDTNKLKELMFTDSREHLESEKHIEVKLQDEHDFDLDEEPAIGKKDPTYTKENLELQERLEWQKLKQTDKPHHPYSSADLEDSTTNEGNARLPIEHDNRFQNVDRYQDRELVQVRAELKETSGAESEKEINLISEQRPDQNQDEVNLRPHSHIKTEETGHHEWDWLMNNEKIDSDEQKFYANERMETLSESDQDKLQNLNYQLKEALQHDLDVMSASRGNDSNEVLSEEDSNPEAAKKITEQPLNPTPNQIPAVPLPVTMPSKQSHIREGSPQFQNQPRSVPPPSPQTKPQSPKEQQPRRTNAPVEFGNKDEAMDLNESASDQEVPKRKKISKTEAVIEPVAKDVSMAEPNESLHSKKETSPASLSKQESKRKQKRSLRRPSSDSDSTKTTNEFEKQRQIIENQKAQLEKMGKKISVMRQGQDRRVSYKGHNPYSADPDLESRPPMDTSFEKDRTGDYQGLGHQRRKVVVAPPFHPPINPRVRVPRPPFDGRDHEFHTMTTAPVDRHLAPAAKWSSLPTTLKLNRNSLVANIQVKHFAALPCQALPKPILKLPMGVPRTPTFSKILCALQLGLLASYLACRKD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W1U3-1", "uniprot_id": "Q9W1U3_DROME", "id": "Q9W1U3-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "aln": "--------------------------------------------------------------------------------MDKIMICIIGSGNWATTIARNVGRNVLNS-QTLDEKVPMYVYEEIVEGRKLTEIINTTHINSKYMPNFELPPNIVAVDDIVTTARDADIIIFAIPPTFVSSCCKTLLGKVKPTAHAVSLIKGFERGDDGQFVLISQIIMRQLKIPCSVLVGCNLAHELAHDHFAEGTVGCRDQKYY---------RVLHDIFKSPTFRVVVTEDADCVEICSTLRNIIAFAAGCSDGMELNENTKGGIIRRGFLEMLQFVDVFYPGC--RMGTFFESCGISDLVTSCYANRNRKLAEAFVKTGKPLSELEHILIPGHEPLGPVTAELVHHMLKKKGLEDKFPLFTTVYRICTGDYPLQRLVETLIKAREDIFHPLHTFQL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::* .*.:::: :. *. : * ::* :* : . *::*** * * **: . ** *::* .: : .**:::* * *: . : : . .: :.. . *:* : : : : ..: * *:* . .* *:. :: :: : :: :.:..:* .::* . . :.: .:.: . : *. *:: * * : **.*.:: :: . . : : : *:. : : : *: * .. : *. : :**** .:: : : : . ", "identical_positions": 47, "similar_positions": 116, "identity": "3.37%" }, { "cls_id": "homologset.agr.SGD:S000005421", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ATT3-1", "uniprot_id": "A0A8I6ATT3_RAT", "id": "A0A8I6ATT3-1", "name": "Metal transporter", "aln": "------------MAAAAAAAAALGVRLRDC------------CSRGAVLLLFFSLSPRPPA--------AAAWLLGLRPE-DTAGGRVSLEGGTLRAAEGTSFLLRVYFQPGPAVPAAPVPAPSLAPGENGTGDWAPRLVFIEEPPGAGSAAPSAVPTRPPGPQRCREQSDWASDVEVLGPLRPGGVAGSALVQVRVRELRKGEAERGGAGGGGKLFSLCA--------------------------WDGRAWHHHGAAGGFLLRVRPRLYGPGGDLLPPAWLRALGALLLLALSALFSGLRLSLLSLDPVELRVLRNSGSAAEQEQARRVQAVRGRG-THLLCTLLLGQAGANAALAGWLYASLPPGVGDPGEDSGEAGVHFPWLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDWALRQEISTFYTREKLLETLR--AADPYSDLVKEELNIIQGALELRTKVVEEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDPDDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKS-HLAIVQRVNNEGEGDPFYEVMGIVTLEDIIEEIIKSEILDETDLYTDNRKKQR---VPHRERRRHDFSLFKLSDSEIRVKISPQLLLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDERNKKAPEHYLYQRSRPVDYFVLLLQGKVEVEVGKEGLRFENGAFTYYGVPAIMTSACS-----DNDVRKVGSLAGSSVFLNRSPSRCSGLNRSESPN-------RERSDFGGSNTQLCS--NNLYTPDYSVHILSDVQFVKITRQQYQNALTACHMDSSPQSPDME-AFTDGDSTKAPTTRGTPQTPKDDPVLTLLSN-RTSLPCSRSDGLRSPGEVVYLRMEEMAFPQEEMPNFEEHKAQQVSLSPVTVPTAAASETECCNIHLDPEASPCSSDSEETMGKKLLRTLSGRKRKKSADGERASEENSNLTPLIT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0GA42-1", "uniprot_id": "CNNM1_MOUSE", "id": "Q0GA42-1", "name": "Metal transporter CNNM1", "aln": "------------MAAAAAAAAALGVRLRDC------------CSRGAVLLLFFSLSPRPPA--------AAAWLLGLRPE-DTAGGRVSLEGGTLRAAEGTSFLLRVYFQPGPPVPAAPVPAPSLAPGENGTGDWAPRLVFIEEPPGAGGAAPSAVPTRPPGPQRCREQSDWASDVEVLGPLRPGGVAGSALVQVRVRELRKGEAERGGAGGGGKLFSLCA--------------------------WDGRAWHHHGAAGGFLLRVRPRLYGPGGDLLPPAWLRALGALLLLALSALFSGLRLSLLSLDPVELRVLRNSGSAAEQEQARRVQAVRGRG-THLLCTLLLGQAGANAALAGWLYASLPPGVGDPGEDSGEAGVHFPWLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDWALRQEISTFYTREKLLETLR--AADPYSDLVKEELNIIQGALELRTKVVEEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDPDDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKS-HLAIVQRVNNEGEGDPFYEVMGIVTLEDIIEEIIKSEILDETDLYTDNRKKQR---VPHRERRRHDFSLFKLSDSEIRVKISPQLLLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDERNKKAPEHYLYQRNRPVDYFVLLLQGKVEVEVGKEGLRFENGAFTYYGVPAIMTSACS-----DNDVRKVGSLAGSSVFLNRSPSRCSGLNRSESPN-------RERSDFGGSNTQLYSSSNNLYTPDYSVHILSDVQFVKITRQQYQNALTACHMDSSPQSPDME-AFTDGDSTKAPTTRGTPQTPKDDPVLTLLSN-RTSLPCSRSDGLRSPGEVVYLRMEEMAFPQEEMPNFEEHRSQQVSLSPVAVPTTAASDPECCNIHLDPEASPCSSDSEENMGKKLLRTLSGRKRKKSADGERASEENSNLTPLIT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRU3-1", "uniprot_id": "CNNM1_HUMAN", "id": "Q9NRU3-1", "name": "Metal transporter CNNM1", "aln": "------------MAAAAAAAAAVGVRLRDC------------CSRGAVLLLFFSLSPRPPA--------AAAWLLGLRPE-DTAGGRVSLEGGTLRAAEGTSFLLRVYFQPGPPATAAPVPSPTLNSGENGTGDWAPRLVFIEEPPGGGGVAPSAVPTRPPGPQRCREQSDWASDVEVLGPLRPGGVAGSALVQVRVRELRKGEAERGGAGGGGKLFSLCA--------------------------WDGRAWHHHGAAGGFLLRVRPRLYGPGGDLLPPAWLRALGALLLLALSALFSGLRLSLLSLDPVELRVLRNSGSAAEQEQARRVQAVRGRG-THLLCTLLLGQAGANAALAGWLYTSLPPGFGGTGEDYSEEGIHFPWLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDWALRQEISTFYTREKLLETLR--AADPYSDLVKEELNIIQGALELRTKVVEEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDPDDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKS-HLAIVQRVNNEGEGDPFYEVMGIVTLEDIIEEIIKSEILDETDLYTDNRKKQR---VPQRERKRHDFSLFKLSDTEMRVKISPQLLLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDEKNKKAPEHYLYQRNRPVDYFVLLLQGKVEVEVGKEGLRFENGAFTYYGVPAIMTTACS-----DNDVRKVGSLAGSSVFLNRSPSRCSGLNRSESPN-------RERSDFGGSNTQLYSSSNNLYMPDYSVHILSDVQFVKITRQQYQNALTACHMDSSPQSPDME-AFTDGDSTKAPTTRGTPQTPKDDPAITLLNN-RNSLPCSRSDGLRSPSEVVYLRMEELAFTQEEMTDFEEHSTQQLTLSPAAVPTRAASDSECCNINLDTETSPCSSDFEENVGKKLLRTLSGQKRKRSPEGERTSEDNSNLTPLIT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q32NY4-1", "uniprot_id": "CNNM3_MOUSE", "id": "Q32NY4-1", "name": "Metal transporter CNNM3", "aln": "-----------MAAAAAAVVGWLGWVLAAF------------CLG-------STAGEAAPA--------PGAGLLNFCTEEDSAPGAGSLRG---RAAPEATLCLRLFCS---------------------------------------GLANSSWTWVAAEGAGCPEGGRATEPEEAAAPTG----EWRALLRLR------AEAGHPRS---------------------------------------------------ALLAVRVEPGGGAAEEAAPPWALGLGAAGLLALAAVARGLQLSALALAPAEVQVLRESGSEAERAAARRLEPARRWA-GCALGALLLLASLAQAALAVLLYG----AAGQRAVP-----------AVLGCAGLVFLVGEVLPAAVSGRWALALAPRALGLSRLAVLLTLPVALPVGQLLELAARPGR----LRERVLELARG-GGDPYSDLSKGVL---------RSRTVEDVLTPLEDCFMLDSGTVLDFSVLASIMQSGHTRIPVYE-EERSNIVDMLYLKDLAIVEPEDCTPLSTITRFYNHPLHFVFNDTKLDAVLEEFKRGKS-HLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESEDYSDTKVRKKTVALGAPLKRKEEFSLFKVSDDEYKVKISPQLLLATQRFLSREVDVFSPLRVSEKVLLHLLKHPSVNQEVTFDESNRLAAHHYLYQRSQPVDYFILILQGRVEVEIGKEGLKFENGAFTYYGVSALTAPSS----------------------AHQSPVSSRQLIRHDVQ--------PEPADGTRS---------CTYCPDYTVRALSDLQLIKVTRLQYLNALLATRAQSLPPSP------ENAELQAIPGSQTRLLGDKSRETAGSTNS-RPSIPVEESPG-RNPGV--------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ACK7-1", "uniprot_id": "D4ACK7_RAT", "id": "D4ACK7-1", "name": "Metal transporter", "aln": "-----------MAAAAAAVAGWLGWVLAAF------------CLG-------STAGEAAP----------GAGLLSFCTEEDGAPGAGSLRG---RAAPEATLCLRLFCP---------------------------------------GLANSSWTWVAPEGAGCPEGGRATEPSEAAAPTG----EWRALLRLR------AEAGHPRS---------------------------------------------------ALLAVRVEPGGGAAEEAAAPWALGLGAAGLLALAAVARGLQLSALALAPAEVQVLRESGSEAERAAARRLEPARRWA-GCALGALLLLASLAQAALAVLLYG----AVGQRAVP-----------AVLGCAGLVFLVGEVLPAAVSGRWALALAPRALGLSRLAVLLTLPVALPVGQLLELAARPGR----LRERVLELARG-GGDPYSDLSKGVL---------RYRTVEDVLTPLEDCFMLDSGTVLDFSVLASIMQSGHTRIPVFE-EERSNIVDMLYLKDLAFVDPEDCTPLSTITRFYNHPLHFVFNDTKLDAVLEEFKRGKS-HLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIRSEILDESEDYSDTKVKKKAVTLGAPLKRKEEFSLFKVSDDEYKVKISPQLLLATQRFLSREVDVFSPLRISEKVLLHLLKHPSVNQEVKFDESNRLATHHYLYQRSQPVDYFILILQGRVEVEIGKEGLKFENGAFTYYGVSALTAPSS----------------------AHQSPVSSRQLIRHDLQ--------PEPADSTRS---------CTYCPDYTVRALSDLQLIKVTRLQYLNALLATRAQSLPPSP------ENAELQAIPGSQTRLLGDKSRETAGPSSS-RRSIPVEESPG-RNPGV--------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NE01-1", "uniprot_id": "CNNM3_HUMAN", "id": "Q8NE01-1", "name": "Metal transporter CNNM3", "aln": "------------MAAAVAAAGRLGWLFAAL------------CLG-------NAAGEAAP----------GPRVLGFCLEEDGAAGAGWVRGGAARDTPDATFLLRLFGP---------------------------------------GFANSSWSWVAPEGAGCR--------EEAASPAG----EWRALLRLRL----RAEAVRPHS---------------------------------------------------ALLAVRVEPGGGAAEEAAPPWALGLGAAGLLALAALARGLQLSALALAPAEVQVLRESGSEAERAAARRLEPARRWA-GCALGALLLLASLAQAALAVLLYR----AAGQRAVP-----------AVLGSAGLVFLVGEVVPAAVSGRWTLALAPRALGLSRLAVLLTLPVALPVGQLLELAARPGR----LRERVLELARG-GGDPYSDLSKGVL---------RCRTVEDVLTPLEDCFMLDASTVLDFGVLASIMQSGHTRIPVYE-EERSNIVDMLYLKDLAFVDPEDCTPLSTITRFYNHPLHFVFNDTKLDAVLEEFKRGKS-HLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIRSEILDESEDYRDTVVKRKPASLMAPLKRKEEFSLFKVSDDEYKVTISPQLLLATQRFLSREVDVFSPLRISEKVLLHLLKHPSVNQEVRFDESNRLATHHYLYQRSQPVDYFILILQGRVEVEIGKEGLKFENGAFTYYGVSALTVPSS----------------------VHQSPVSSLQPIRHDLQ--------PDPGDGTHS---------SAYCPDYTVRALSDLQLIKVTRLQYLNALLATRAQNLPQSP------ENTDLQVIPGSQTRLLGEKTTTAAGSSHS-RPGVPVEGSPG-RNPGV--------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3TWN3-1", "uniprot_id": "CNNM2_MOUSE", "id": "Q3TWN3-1", "name": "Metal transporter CNNM2", "aln": "MIGCGACEPEVKMAGGQAAAALPTWKMAARRSLSARGRGVLQAAAGRLLPLLLLSCCWGAGGCTAAGENEETVIIGLRLE-DTNDVSFMEG-GALRVSERTRVKLRVYGQNINNETWSRIAFTEHERRRHT-----------------PSERGLGGPAPPEPDSGPQRCGIRTSDIIILPHIILNR-RTSGIIEIEIKPLRKMEKSKSYYLCTSLSTPALGAGGSGSASGTVGGKGGAGVAGLPPPPWAETTWIYHDGEDTKMIVGEEK------KFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQG-NYLLCSLLLGNVLVNTTLTILLDD----IAGS------------GLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLR--VTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFE-GERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKS-HLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKK----VAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPECYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTASPVPLSLSRTFVVSRTEVLAAGSPGENKSPPRPCGLNHSDSLSRSDRIDAMTP-TLGSSNNQLSSSFLQVYIPDYSVRALSDLQFVKISRQQYQNALMASRMDKTPQSS------DSENTKIELTLTELHDG-LPDETANLLNE-QNCVSHNKANHSLHSEGAI------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U2P1-1", "uniprot_id": "CNNM2_RAT", "id": "Q5U2P1-1", "name": "Metal transporter CNNM2", "aln": "MIGCGACEPEVKMAGGQAAAALPTWKMAARRSLSARGRGVLQAAAGRLLPLLLLSCCCSAGGCTAAGENEETVIIGLRLE-DTNDVSFMEG-GALRVSERTRVKLRVYGQNINNETWSRIAFTEHERRRHT-----------------PGERGLGGPAPPEPDSGPQRCGIRTSDIIILPHIILNR-RTSGIIEIEIKPLRKMEKSKSYYLCTSLSTPALGAGGSGSASGTVGGKGGAGVAGLPPPPWAETTWIYHDGEDTKMIVGEEK------KFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQG-NYLLCSLLLGNVLVNTTLTILLDD----IAGS------------GLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLR--VTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFE-GERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKS-HLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKK----VAHRERKQDFSAFKQTDSETKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPECYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTASPVPLSLSRTFVVSRTEVLAAGSPGENKSPPRPCGLNHSDSLSRSDRIDAMTP-TLGSSNNQLSSSFLQVYIPDYSVRALSDLQFVKISRQQYQNALMASRMDKTPQSS------DSENTKIELTLTEMHDG-LPDETANLLNE-QNCVSHNKANHSLHSEGAI------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H8M5-1", "uniprot_id": "CNNM2_HUMAN", "id": "Q9H8M5-1", "name": "Metal transporter CNNM2", "aln": "MIGCGACEPKVKMAGGQAAAALPTWKMAARRSLSARGRGILQAAAGRLLPLLLLSCCCGAGGCAAVGENEETVIIGLRLE-DTNDVSFMEG-GALRVSERTRVKLRVYGQNINNETWSRIAFTEHERRRHS-----------------PGERGLGGPAPPEPDSGPQRCGIRTSDIIILPHIILNR-RTSGIIEIEIKPLRKMEKSKSYYLCTSLSTPALGAGGSGSTGGAVGGKGGSGVAGLPPPPWAETTWIYHDGEDTKMIVGEEK------KFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQG-NYLLCSLLLGNVLVNTTLTILLDD----IAGS------------GLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLR--VTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFE-GERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKS-HLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKK----VAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPEYYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTASPVPLSLSRTFVVSRTELLAAGSPGENKSPPRPCGLNHSDSLSRSDRIDAVTP-TLGSSNNQLNSSLLQVYIPDYSVRALSDLQFVKISRQQYQNALMASRMDKTPQSS------DSENTKIELTLTELHDG-LPDETANLLNE-QNCVTHSKANHSLHNEGAI------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AJ29-1", "uniprot_id": "A0A8M3AJ29_DANRE", "id": "A0A8M3AJ29-1", "name": "Metal transporter", "aln": "------------MA--EPSVPVPPRKMAS-----------LSRVRAFTLIFLTASSCLITPTSGKEGGGEETVIIGLRLE-DTDDISFMDR-GFLRVSERSRVRLRVYGQNINNETWSKIAFTEHERSRVIG----------------NIDSSSGDNQSQEDTSGLHPCGIRTSDILILPNIVLNR-KTSGTVEIEVKPLRKTERSKAYYLCIATSTPAVAG---------------------AHDPWTENTWIYHDGEDTKVIVVEEK------KFLLPFWLQVIFISMLLCLSGMFSGLNLGLMALDPMELQIVQNCGTEKEKNYARKIEPVRSQG-NYLLCSLLLGNVLVNTTLTILLDD----IAGS------------GLIAVVMSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMLLTFPASYPVSKLLDYLLGQEIGTVYNREKLLEMLR--VTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGDATLDFNSMSEIMESGYTRIPVFE-GDRSNIVDLLFVKDLAFVDPDDCTPLKTITKFYSHPLHFVFNDTKLDAMLEEFKKGKS-HLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNKTKKK----ITHRERKQDFSAFKHMDNEMKVKISPQLLLATLRFLATEVEPFSPSQMSEKILLRLLKHPNVIQEVKYNDKNKKAIEHYLFHRNKPVDYFILILQGKVEVEAGKEGLRFEAGAFSSYGMMALTASPVPLSLSRTFVVSRAESVAGSPGMENKSPPRSFGLNHSDSLNRSERIEVITP-SLGSSNNQLN-AFLQIYVPDYSVRAVSDVQYIKVTRQQYQNAVMASRIDKTPQSS------ESEYTKIEMTLTELHDG-LTDETTTLFNQTQNCVVHNKSNHTGHSEGPI------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q69ZF7-1", "uniprot_id": "CNNM4_MOUSE", "id": "Q69ZF7-1", "name": "Metal transporter CNNM4", "aln": "------------MAPGGGGGRRDGWPARGR----------LLLAA---LLLLWTRAASGQ------SSPQQSVILGMRLA-SCNKSCGMNPDGIIFVSEGSTVNLRLYGHSLGDISSNLISFTEVD--------------------------------DAEAVHNSTNCLELTKDLVVQRLVNVSRGNTSGMLVVITKFLRRSENMKLYALCTRPR--------------------------------ADGPWTRWTDKDSLLFMVEEH------GRFLPLWLHILLVMVLLVLSGIFSGLNLGLMALDPMELRIVQNCGTEKERKYARKIEPIRRKG-NYLLCSLLLGNVLVNTSLTILLDN----LIGS------------GIMAVASSTIGIVIFGEILPQALCSRHGLAVGANTIVLTKVFMLLTFPLSFPISKLLDFVLGQEIRTVYNREKLMEMLK--VTEPYNDLVKEELNMIQGALELRTKTVEDIMTQLHDCFMIRSDAILDFNTMSEIMESGYTRIPVFE-DEQSNIVDILYVKDLAFVDPDDCTPLKTITRFYNHPVHFVFHDTKLDAMLEEFKKGKS-HLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESDMYTDNRTRKR----VSVKN-KRDFSAFKDTDNELKVKISPQLLLAAHRFLATEVPQFSPSLMSEKILLRLLKYPDVIQELRFNEHNRYCVRHYLYTRNKPADCFVLILQGKVEVEAGKENMKFETGAFSYYGTMALSVAPP-----------------------DRSPALPTPLSRSASLSYPDRNTDLTSTSLAGS-NQFGSCILGQYVSDFSVRALTDLQYIKITRQQYQNGLMASRMDNSPQPT------FDGCATCSENFMERPELPPVDETTTLLNE-RNSLLHRAS-----EEETI------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C588-1", "uniprot_id": "CNNM4_RAT", "id": "P0C588-1", "name": "Metal transporter CNNM4", "aln": "------------MAPGGGGGRRDGWPARGR----------LLLAAL--LLLLWTRAASGQ------SSPQQSVILGMRLA-SCNKSCGMNPDGIIFVSEGSTVNLRLYGHRLGEISSNLISFTEVD--------------------------------DAETVHNSTNCLELTKDLVVQRLVNVSRGNTSGMLVVITKFLRRSENMKLYALCTRTR--------------------------------ADGPWLKWTDKDSLLFMVEEH------GRFLPLWLHILLVLVLLVLSGIFSGLNLGLMALDPMELRIVQNCGTEKERRYARKIEPIRRKG-NYLLCSLLLGNVLVNTSLTILLDN----LIGS------------GIMAVASSTIGIVIFGEILPQALCSRHGLAVGANTIVLTKIFMLLTFPLSFPISKLLDFVLGQEIRTVYNREKLMEMLK--VTEPYNDLVKEELNMIQGALELRTKTVEDIMTQLHDCFMIRSDAILDFNTMSEIMESGYTRIPVFE-DEQSNIVDILYVKDLAFVDPDDCTPLKTITRFYNHPVHFVFHDTKLDAMLEEFKKGKS-HLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESDTYTDNRTRKR----VSMKN-KRDFSAFKDADNELKVKISPQLLLAAHRFLATEVPQFSPSLMSEKILLRLLKYPDVIQELRFDEHNKHCTRHYLYTRNKPADCFILILQGKVEVEAGKENMKFETGAFSYYGTMALSLAPP-----------------------DRSPAHPTPLSRSASLSYPDRNTDMTPSSLAGS-NQFGSCILGQYVSDFSVRALTDLQYIKVTRQQYQNGLLASRMDNSPQLT------LDGCATCTENLSERPELPVVDETTTLLNE-RNLLLHRAS-----QEGTI------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P4Q7-1", "uniprot_id": "CNNM4_HUMAN", "id": "Q6P4Q7-1", "name": "Metal transporter CNNM4", "aln": "------------MAPVGGGGRPVGGPARGR----------LLLAAPVLLVLLWALGARGQ------GSPQQGTIVGMRLA-SCNKSCGTNPDGIIFVSEGSTVNLRLYGYSLGNISSNLISFTEVD--------------------------------DAETLHKSTSCLELTKDLVVQQLVNVSRGNTSGVLVVLTKFLRRSESMKLYALCTRAQ--------------------------------PDGPWLKWTDKDSLLFMVEEP------GRFLPLWLHILLITVLLVLSGIFSGLNLGLMALDPMELRIVQNCGTEKERRYARKIEPIRRKG-NYLLCSLLLGNVLVNTSLTILLDN----LIGS------------GLMAVASSTIGIVIFGEILPQALCSRHGLAVGANTILLTKFFMLLTFPLSFPISKLLDFFLGQEIRTVYNREKLMEMLK--VTEPYNDLVKEELNMIQGALELRTKTVEDIMTQLQDCFMIRSDAILDFNTMSEIMESGYTRIPVFE-DEQSNIVDILYVKDLAFVDPDDCTPLKTITRFYNHPVHFVFHDTKLDAMLEEFKKGKS-HLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESDMYTDNRSRKR----VSEKN-KRDFSAFKDADNELKVKISPQLLLAAHRFLATEVSQFSPSLISEKILLRLLKYPDVIQELKFDEHNKYYARHYLYTRNKPADYFILILQGKVEVEAGKENMKFETGAFSYYGTMALTSVPS-----------------------DRSPAHPTPLSRSASLSYPDRTDVSTAATLAGSSNQFGSSVLGQYISDFSVRALVDLQYIKITRQQYQNGLLASRMENSPQFP------IDGCTTHMENLAEKSELPVVDETTTLLNE-RNSLLHKAS-----HENAI------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B7P9G0-1", "uniprot_id": "UEX_DROME", "id": "A0A0B7P9G0-1", "name": "Unextended protein", "aln": "----MNTYFISFITIIIFANGINGTSVDTSN--------KLLLQKANDFNLSQNLSSSRTR----RTIANSFRIVGIRLEDETVETKNGIP----TVLVDKEQQFRVFGSGLEENTAITFTNEKND---------------------------YGGPCLKPATDLFTPIEVSSNGFSALYSVKFPSFINEFFICAKTAEKTTNHSKAATTTPLEHQ------------------------------------------GNSDFLKIKTF------EPLIPVWLAIIIIVTCLGFSALFSGLNLGLMSMDRTELKILRNTGTEKEKKYASKIAPVRDQG-NYLLCSILLGNVLVNSTFTILLDG----LTSG-------------LFAVIFSTLAIVLFGEITPQAVCSRHGLAIGAKTILVTKTVMAITAPLSYPVSRILDKLLGEEIGNVYNRERLKELVR--VTNDVNDLDKNEVNIISGALELRKKTVADVMTHINDAFMLSLDALLDFETVSEIMNSGYSRIPVYD-GDRKNIVTLLYIKDLAFVDTDDNTPLKTLCEFYQNPVHFVFEDYTLDIMFNQFKEGTIGHIAFVHRVNNEGDGDPFYETVGLVTLEDVIEELIQAEIVDETDVFVDNRTKTR-----RNRYKKADFSAFAERREVQTVRISPQLTLATFQYLSTAVDAFKKDVISELILRRLLN-QDVFHNIKTKGKSKDDPSLYIFTQGKAVDFFVLILEGRVEVTIGKEALMFESGPFTYFGTQALVPNVVID-----------------------SPTQMGSLQSLNMDS----------------------KIRQSFVPDYSVRAISDVIYITIKRVLYLTAKKATLLEKSRKSGTFSSETFDDEVERLLHSITENEKPSCFAQNQSTRRLSNRSINSSPTNMNRSPDFVYNSVDEAIQDDTKLKNIKHADNVTTSISLVAAELEDLHSGEQDTTAASMPLLPKLDDKFESKQSKP------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12296-1", "uniprot_id": "MAM3_YEAST", "id": "Q12296-1", "name": "Protein MAM3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------MSFLPLRSRSRSGAPHWVYIILYHIFTIPKIYSLPLLSGSHVLNSRDVADSGHSVG----------------------------------------------------------------DEASVTTYYIISIILVLLGGVFAGLTLGLMGQDEVYLKVISTSGSNSEKKLAKRVLDLISRGKHWVLVTLLLSNVITNETLPIVLDR----CLGG------------GWQAVVSSTILIVIFGEIIPQSVCVKYGLQVGAFFCPFVLVLMYLMYPVAYPIATLLDYMLGEDHGTMYKKSGLKTLVTLHRTMGVERLTKDEVTIISAVLDLKAKRVEEIMTPIENVFTMSADTILDDKTVEKIFNSGFSRIPIFLPNEPNNFIGMLLVRVLISYDPDDCLPIS---HFPLATLPETSPNTSCLNILNYFQEGKA-HMCVVSKEPGSSHG-----AIGVLTLEDVIEELIGEEIVDESDVFVDMHQHIMRQQPGPLSKRHITSYLHHLYTSSHKEHKAADQADESSPLLSPSNSNHPSEHPQQDLNNKSWKQKSNDGYDRSNAVLSPTPQVTEHGTIIPSNLASNPLNVNKSFVTIKKPANVPKIITTHTPHSSKEPSPAP-----------------------HSNDKSLSAEEQQLLS-----DHAELSRQAVLHTQRSGQPTQVTTSTKTTRNSPDSISIPNSGANHGNENQNVTISTSYQNTKNGIVESVITVKGVPKTIIGPAKDWDESKSEYGNENINQENSNRSDDRESSSSNASLFSSIKNKFKNENANNNDRSNFTDSLSRTSNYDANGSSSTIKR----------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : :..: ** *. :. :::: *: *: * :: . * ::** .: ::. * . .. .: :.: .*: * ::. : * :.. . : * . *:. :*: :. : . * * : : : * :::* : : * : : ** : .*:.**.:***:: : *:: :* :: * :.:* *: .* .: . : ::: *:.*. *:..* : ....* .:*::****:***:* **:**:: : * : : . :.: :: . .: : : : . . . . : *: . .. *: . : : * . :.: * : . : . .. . ", "identical_positions": 58, "similar_positions": 150, "identity": "5.63%" }, { "cls_id": "homologset.agr.SGD:S000005423", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96CW1-1", "uniprot_id": "AP2M1_HUMAN", "id": "Q96CW1-1", "name": "AP-2 complex subunit mu", "aln": "MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKR---SNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILD-FGYPQNSETGALKTFITQQGIKSQHQTKEEQ-------------------------SQITSQVTG------------QIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKG----TADETS-----------KSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGR-TKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKK---KWARPPISMNFEVPFAP-SGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P84091-1", "uniprot_id": "AP2M1_MOUSE", "id": "P84091-1", "name": "AP-2 complex subunit mu", "aln": "MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKR---SNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILD-FGYPQNSETGALKTFITQQGIKSQHQTKEEQ-------------------------SQITSQVTG------------QIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKG----TADETS-----------KSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGR-TKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKK---KWARPPISMNFEVPFAP-SGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P84092-1", "uniprot_id": "AP2M1_RAT", "id": "P84092-1", "name": "AP-2 complex subunit mu", "aln": "MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKR---SNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILD-FGYPQNSETGALKTFITQQGIKSQHQTKEEQ-------------------------SQITSQVTG------------QIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKG----TADETS-----------KSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGR-TKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKK---KWARPPISMNFEVPFAP-SGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7ZW98-1", "uniprot_id": "AP2MB_DANRE", "id": "Q7ZW98-1", "name": "AP-2 complex subunit mu-B", "aln": "MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKR---SNIWLAAVTKQNVNAAMVFEFLYKMCDVMTAYFGKISEENIKNNFVLIYELLDEILD-FGYPQNSETGALKTFITQQGIKSQHLTKEEQ-------------------------SQITSQVTG------------QIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIDKQGKGG---TTDDTG-----------KSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEYELMRYRTTKDIILPFRVIPLVREVGR-TKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMVGMKESQISAEIELLPTNDKK---KWARPPISMNFEVPFAP-SGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6NWK2-1", "uniprot_id": "AP2MA_DANRE", "id": "Q6NWK2-1", "name": "AP-2 complex subunit mu-A", "aln": "MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKR---SNIWLAAVTKQNVNAAMVFEFLYKMCDVMTAYFGKISEENIKNNFVLIYELLDEILD-FGYPQNSETGALKTFITQQGIKGQHQTKEEQ-------------------------SQITSQVTG------------QIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIDKQGKGG---TTDDAG-----------KSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEYELMRYRTTKDIILPFRVIPLVREVGR-TKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKK---KWARPPISMNFEVPFAP-SGLKVRYLKVFESKLNYSDHDVIKWVRYIGRSGIYETRC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O62530-1", "uniprot_id": "O62530_DROME", "id": "O62530-1", "name": "", "aln": "MIGGLFVYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHIKR---ANIWLAAVTKQNVNAAMVFEFLLKIIEVMQSYFGKISEENIKNNFVLIYELLDEILD-FGYPQNTDSGTLKTFITQQGIKS--ATKEEQ-------------------------MQITSQVTG------------QIGWRREGIKYRRNELFLDVLEYVNLLMSPQGQVLSAHVAGKVVMKSYLSGMPECKFGINDKIVMESKGRGLSGNSEAETS-----------RSGKPVVVIDDCQFHQCVKLSKFETEHSISFIPPDGEFELMRYRTTKDISLPFRVIPLVREVGR-TKMEVKVVLKSNFKPSLLGQKIEVKIPTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLETDTKK---KWTRPPISMNFEVPFAP-SGFKVRYLKVFEPKLNYSDHDVVKWVRYIGRSGLYETRC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99186-1", "uniprot_id": "AP2M_YEAST", "id": "Q99186-1", "name": "AP-2 complex subunit mu", "aln": "MISGVLVYSSRGELVLNKFFKNSLKRSISDIFRVQVINN-LDVRSPVLTLGSTTFHHIRSRHGDNLWLVTITRSNANSAAIWEFLYKLDAVMNAYR-LDREEALKEEFMIVHEMLDIMLGGNGIPIDTELNSVIAQMSVKPVRNMGGLLDSPDGNDVLSSSSSPTSSAGELHFPKFLTKRSSSFLGQGDSTSDFYDNNKITWRPKGIIHKKDEVFLYVNERINILVSRDGSILKSYVDGTIDITTHLSGTPICRFGLNDSLGMQSEDEKKWLAQQQRHSGSDFGNKNFIPKAAAGSVLLEDCKFHECVSLDKFNRNHIIEFVPPDGSMELMKYHVRDNINLPFKVTPIVTHSTRDNEIDYRITLKSLFPGKLSAKDVVLHIPVPPSTVDCKISVSNGHCKFVPEENAMIWRFNKYNGLTENTLSAVTVSTSDTTQLNLQQWTRPPISLEFEVMMFSNSGLVVRYFTISG---KDSKHRAVKWIKYISKAGSYEVRY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.*:::*. :**:::.:.:::.: *. * ***:**: :***** .:. *:*.*:: *:**.::*:.*.*:* ::*** *: ** :* ** :*::*::::*:** :*. * * ::: .:: : :: : ::. :. : :*.. * :* ** :** ::::*:** * * :*:*:* :*.:*.::* * : :.::*** * *:**:**.: ::.:.. . ::. : ::** **:** *.**: :: *.*:****. ***:*:. .:* ***:* *:* . * .::: ::.:** * .* .:.: ::**.* .* . :: :*:.*: ..***::*:::: *:.*. :** : :*:*****::*** : . **: ***:.: : *.* .:**::**.::* **.* ", "identical_positions": 142, "similar_positions": 180, "identity": "28.63%" }, { "cls_id": "homologset.agr.SGD:S000005426", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1RLT2-1", "uniprot_id": "A0A8M1RLT2_DANRE", "id": "A0A8M1RLT2-1", "name": "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A", "aln": "MEAEQQIQSESKSNDLASSTPPKAPSEASPPAVPSAPARPRRPQRSPRVEGSIDVSEPKPPESPKPSSHDEPNAEAQAQLRVHAPPAALKLSGHASVARSHISMRAASLPQAPSYKPPSTESVVHPQRALSVAGTADTQPQVAEDFRIHIVTWNVGSAMPPEDITNLLGLNVGDGNTDMYIIGLQEVNSMINKRLKDVLFTDQWSEVCMDALSPFGYVLATSQRMQGMLLLVFAKYFHLPFLRGIQTQTTRTGLGGIWGNKGGVSARMTVFGHSICFLNCHLPAHMENTEQRMEDFESILQQQQFDGQAATGVLDHDVVFWFGDLNFRIEDLEMQVVKGAIDNNKLSVLWEKDQLNIAK--DSETVLEGFHEGPLKFPPTYKFDVGTDTYDT---------SGKKRMPAWTDRILWRLRPMAQVSNSTSKRSSLSGLTSG------TRVSQHFYRSHMEYTVSDHKPVSSVFTLQFPYKVDMPLVTIFVEDEWREISDAVAKFKVAPNFARSSWDWIGIYKVGFKHHKDYVAYTWAKQEESDFLRQEHQVNFTEEELPKESGDFILGYYSNNTSSIVGITEPFQIQLPASAAAGLSPSDSSDFTSDDEVKKPDSGDSSPETEDPVSSRLTEEQMAKPSRPHARPRHGKHHAGSAVQPSDEPENSGKAAAEPEEP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AHJ9-1", "uniprot_id": "A0A8M3AHJ9_DANRE", "id": "A0A8M3AHJ9-1", "name": "", "aln": "MSSSMEEISEYFSEKLQRQRSDSAASSST----QSTSSRQHVRQR----------------LAMLLTCVDDLDTDHKLQTQVAKT-----LDEAFLVCR-------------------------------QIAGRPKKNP-----FRLYVVTWNVATAEPPDDVNALLQLNSPK-KPDLYVIGLQEVRAAPLKFVSDLAFEDSWSHLFMDTLSPLHYIKVSSIRMQGLLLLFFSKLEHVPFIRDIQVTYTRTGLYGYWGNKGGVTIRLSFYGHMLCFLNCHLTAHMNYASQRVDEFEHILDAQNFNTKNTPHVLDHKVVFWFGDLNFRIEDHGMLFVRNCITSQRFNLLWPKDQLTMMK--QKEVILQKFEEGPLDFQPTYKFDLNSDNYDTRVQTTWFGFNGKKRKPAWCDRILWRVKPKASLTENTNEEEPEKQQEEEREDEFPLKMTQEYYTSKMEYGISDHKPVIGIFRLELRKMYETPLVQVFAEGEWSADFDAVITYRLLQAFASSAWDWIGLYKVGFKSVSDYITYAWVKDDQVSFNEELFQVYMNKDEIPVLGGECVLCYYSSNLQCIVGISQPFKVQ---------------------------------ESRAAIEEGLVPENINGLNQALAS-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08227-1", "uniprot_id": "INP54_YEAST", "id": "Q08227-1", "name": "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP54", "aln": "MNKTNWKVSVTTFNCGKEFPVENSKAIVK----------------------------------QLLFPYDDGISQLELQDLYVLG------------------------------------------------------------FQEVVPIWQGSFPAVNRDLIDRITTTAVN---------------CLNEKVSATQGDEQYSCLGVNSLGAITIIVLYNNNALKVKDDILKRNGKCGWFG----THLKGGTLISFQMTRNGEENWERFSYICAHLNAN--EGVNNRNQRIDDYKRIMS-----EVCDSEVAKSDHFFFLGDLNFRVTSTYDPTTNYSSTTTLRRLLENHEELNLLRKGEDEPLCKGFQELKITFPPTYKFKLFEKETYN-----------TKRIPSWCDRILYKSYAVPTFAQEG---------------------TYHSVPRSNALLFSDHQPVN--LTVRLPRSTGTPVPLSLHIEKYPLSWSSGLIGQIGDAVIG-YCGWLVTKNVHYWILGSLLLYLLLKIL---------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. * : .: : . *: :: : * *: : *: . . *: : . . : :. :.:* : :::*..: : . . : .: : : :: : * : . . . :.: ..**.: :: .**::::: *:. . * . . .*::******: . .. . . :* :::*.: : :.* : : *.* : * *****.: . . .** *:* ****:: . . .::. : . .***:** : :.: *: : :: .: :: . .*: :* : . : * * ", "identical_positions": 52, "similar_positions": 126, "identity": "7.72%" }, { "cls_id": "homologset.agr.SGD:S000005427", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACD4-1", "uniprot_id": "D4ACD4_RAT", "id": "D4ACD4-1", "name": "Pseudouridylate synthase RPUSD2", "aln": "--MTPSYRDPEAACHAVMWRSVPGCLRYIVQWQVALWSHS-FVRTWGSCGKAMTEALSAQAEAAD-------GLKALIEQNGDTGSDTRGEPHLELLEPAT-------------------------------------------------------------------------------------------------------------VGKQVPESGEQAQGGEEQLPGNGEQAPTPVAD------SGKRKKRRG----ATGERVVPPPKKRRTGVSFSDEHFAETTYYFEGGLRKVRPYYFDFQTYCKGRWVGRSLLHVFSTEFRSQPLAYYEAAVRAGRLHLNEEPVQDLNIVLKDNDFLRNTVHRHEPPVTAEPIRLLAENDDVVVIDKPSSIPVHPCGRFRHNTVIFILGKEHQLKELHPLHRLDRLTSGVLMFAKTAAVSEKIHEQVRDRQLEKEYVCRVAGEFPDKEVICKEPILVVSYKVGVCRVDPQ----GKPCETVFQRLSYNGRSSVVQCRPLTGRTHQIRVHLQFLGHPILNDPIYN-STAWGPSRGQGGHIP-KTDEELLRDLVAEHQAKESLSMLDLCEGDLA---------PG---------------------LIDSTAPSSELGKD-----SLEG---LATAAQKIDG-------------MVDEASQHPDT----PGKAAKADVS--------QQTDPLCAECRVLRQDPLPQDLVMFLHALRYKG------------------------------------------------PDFEYVSPIPAWAQADWQED---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q149F1-1", "uniprot_id": "RUSD2_MOUSE", "id": "Q149F1-1", "name": "Pseudouridylate synthase RPUSD2", "aln": "-----------------MWRGVPGCLRDIVQWQVALWSHS-FVRTWGSCGKAMTEALSAQAEAAG-------GLKALVQPNGDAGSNTSGEPLLERLEPAA-------------------------------------------------------------------------------------------------------------VGKQVPESGDQAQGGEGQLPSNGEQTPAPVAD------SGKRKKRRG----ATGERVVPPPKKRRTGVSFSDEHFAETTYYFEGGLRKVRPYYFDFQTYCKGRWVGRSLLHVFSTEFRSQPLSYYEAAVRAGRLHLNEEPVQDLSIVLKDNDFLRNTVHRHEPPVTAEPIHLLAENNDVVVIDKPSSIPVHPCGRFRHNTVIFILGKEHQLKELHPLHRLDRLTSGVLMFAKTAAVSEKIHEQVRDRQLEKEYVCRVAGEFPDKEVICKEPILVVSYKVGVCRVDPR----GKPCETVFQRLSYNGRSSVVQCRPLTGRTHQIRVHLQFLGHPILNDPIYN-STAWGPSRGQGGHIP-KTDEELLRDLVAEHQAKESLSMLDLCESDLT---------PG---------------------LIDSTAPSSELAKD-----SLEG---LATAAQKIDG-------------IAEAAPQHLDT----PEKAAKADVT--------QETDPLCAECRVLRQDPLPQDLVMFLHALRYKG------------------------------------------------PDFEYVSPIPAWARDDWQED---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IZ73-1", "uniprot_id": "RUSD2_HUMAN", "id": "Q8IZ73-1", "name": "Pseudouridylate synthase RPUSD2", "aln": "-----------------MWLDRRGWLRVLGHWRYDLRRPS-FTRTWSGDKGPMAETVSTQVGTEG-------GLRASHQQNGDAGGDAKVE--LSPGPPKP-------------------------------------------------------------------------------------------------------------AGREVEP-----------APVGGEHPSAAAPG------PGKHKKRRG----ATRERVVPPPKKRRTGVSFGDEHFAETSYYFEGGLRKVRPYYFDFRTYCKGRWVGHSLLHVFSTEFRAQPLAYYEAAVRAGRLQLNEKPVQDLNIVLKDNDFLRNTVHRHEPPVTAEPIRLLAENEDVVVVDKPSSIPVHPCGRFRHNTVIFILGKEHQLKELHPLHRLDRLTSGVLMFAKTAAVSERIHEQVRDRQLEKEYVCRVEGEFPTEEVTCKEPILVVSYKVGVCRVDPR----GKPCETVFQRLSYNGQSSVVRCRPLTGRTHQIRVHLQFLGHPILNDPIYN-SVAWGPSRGRGGYIP-KTNEELLRDLVAEHQAKQSLDVLDLCEGDLS---------PG---------------------LTDSTAPSSELGKD-----DLEE---LAAAAQKMEE-------------VAEAAPQELDTIALASEKAVETDVMN-------QETDPLCAECRLVRQDPLPQDLVMFLHALRYKG------------------------------------------------PGFEYFSPMPAWAQDDWQKD---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P3Z9-1", "uniprot_id": "A0A8M1P3Z9_DANRE", "id": "A0A8M1P3Z9-1", "name": "Pseudouridylate synthase RPUSD2", "aln": "----------------MVHVWKITHIQALTLLRFGRRQNSEFIKRVYQNRNVSVETQRTHCSVLN-------VRRNSTQVES---SKHPVNTHLSLYDMDN-------------------------------------------------------------------------------------------------------------KGEEGGGDTDSTVKTSCGKRKNEETDEAAGQC------SGRKRKRGGGKQLRPGERYVPPPQKRNTGVSFNQEHFAETSYYFEGGLRKVHPYYFDFKSYCKGRWIGKTLLDVFKKEFRAESLDYYNAAVKEGRIKLNETPVDDLNVVLKNNDLLRNTVHRHEPPVCGQPLKLLVDDGEVVVVDKPSSLPVHPCGRYRHNTVIFILGKEKGLVGLHTVHRLDRLTSGVLLFARTLEVSKKLDVMVRERQLEKEYVCRVEGEFPEAEVVCEEPILVVSFRVGLCRVDPK----GKESRTIFQRLSFNGRSSVVRCRPLTGRTHQIRVHLQFLGFPILNDPIYG-SSAWGPNRAKGGLVG-MSDEELLEALIEEHRSKESLHLLDLPDEEVSGKTKCKDGAQGRNE---------------QITAIESSSGSSEVSLD-----EVKAESRQVVQQSTSES-------------VGEINGARKDK-DLASDDASRTGRSKD------FVRDHLCGECKIVRPDPTEKELIMYLHALRYKG------------------------------------------------PDFEYSTQLPDWAKEDWIQD---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKU8-1", "uniprot_id": "Q9VKU8_DROME", "id": "Q9VKU8-1", "name": "Pseudouridylate synthase RPUSD2", "aln": "MESS-------------------KLLRNAQTQHGDASSVD--VENIFLHR----HMLYTNPTSD----------------GNLHDREDSPECVWCPDDKDG-----------------------SPAE------------------------------------------------------------------------------------SKDPP-----------ISISEEKSETQSKE----VLSEKRKASSTDDEGHVKKVKLEANSLKTKRPGFSDERYDETSYYFENGLRKVYPYFFTFTTFAKGRWVDEKILDVFVREFRAAPPEEYERSLEAGKLTVNSEKVP-KDYKIKHNDLLANVVHRHEVPVTSQPIKIVYMDKDIVVVNKPASIPVHPCGRYRHNTVVFILAKEHNLKNLRTIHRLDRLTSGLLLFGRTAEKARELELQIRTRQVQKEYVCRVEGRFPDGIVECNEKIDVVSYKIGVCKVSPK----GKDCKTTFKRIGEVGSDSIVLCKPLTGRMHQIRVHLQFLGYPISNDPLYN-HEVFGPLKGRGGDIGGITEEQLISNLISIHNAENWLGLE--GDQIVSG--EIKDVAAS--------------------TSVV-EAPSVVQAP-----INSETEKPVISKNLEPSN--------------DATAQIATQTCYEEPDRSFDS---------KKTTSDPQCSECKINYRDPGTKDLIMYLHAWKYKG------------------------------------------------VGWEYETELPEWACNSNIDYDKV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKV0-1", "uniprot_id": "Q9VKV0_DROME", "id": "Q9VKV0-1", "name": "Pseudouridylate synthase RPUSD2", "aln": "MQNSPAPCAWYLPWSLAAQQHQQKMLQMQSPFLDKMGATS--VGGIFAGQPQMQQQLSPNTAAAPPANYQQPALHPSAAPGAPHFHMGSPYSHLAPQLLNAGQLNQNALMHSAMFSSLPLGAYYAPAAGAGHSAFGGVPLTTAAQQSLLAATGGATAGHLANQQTTAQVPVQVPVQMAQRTAPAACSMVQPLNCLPHQELNHLSSINLNLLRSPAPPLPAIQVLPSAEVPINKKTTSPRDSENLKIKVPEKRKTDDNDQIKELKKAKLETKALKAKRPGFTDERYQETSYYMENGLRKVYPYYFTFTTFTKGRWVGEKILDIFSREFRAHPAEEYERCIQTGTLTVNFEKVP-IDYRLKHNDLLANIVHRHEVPVTCQPIKIVHMDEDIVVVNKPASIPVHPCGRYRHNTVVFILAKEFNLKNLRTIHRLDRLTSGLLLFGRSPKKARQMEQQIRNRQVEKEYICRVEGVFPDGIVECKEPIEVVSYKIGVCKVSAK----GKDCTTTFQKLSQNGTTSVVLCKPLTGRMHQIRVHLQYLGYPILNDPLYN-HEVFGPLKGRSGDIGGKSDEELIRDLINIHNAENWLGID--CDSDISMFKSTKDEADR--------------------ESLSSEHTSVVHHSDDDGCVNSRETTPPCNEPQQPENSVKLLETTNAVKEYQVAAQKSSSEICPAPLDAVESPLNGGGCNVGKVTVDEHCYECKVHYRDPKSKDLIMYLHAWKYKG------------------------------------------------PGWEYETELPNWARNDWDHLDSA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12362-1", "uniprot_id": "RIB2_YEAST", "id": "Q12362-1", "name": "Bifunctional protein RIB2", "aln": "-------------------------------MEDSNNEASDDFNNLLNKEIESAKEVKLRKFANR------------------------------------------------------------------------------------------------------------------------------------------------------------------NNNRNENSSKVKDAS-------------------GFRLRVIQTDGHKTKKTDP------DYEVTIDGPLRKIEPYFFTYKTFCKERWRDRKLVDVFVSEFRDREPSYYSKTIAEGKVYLNDEPAN-LDTIIRDGDLITHKVHRHEPPVTSKPIDIVFEDEDILVIDKPSSIPVHPTGRYRFNTITKMLERQLGYS-VHPCNRLDKPTSGLMFLAKTPLGADRMGDQMKAREVTKEYVARVKGEFPIGIVEVDKPVRSVNPKVALNAVCEMSDENAKHAKTVFQRVSYDGQTSIVKCKPLTGRTHQIRVHLQYLGFPIANDPIYSNPDIWGPDLGRGGLQNYDDIVLKLDAIGKTNPAESWIHPHSEGEYLLGRQCEECEAEMYTDPGTNDLDLWLHAFRYESLERNSDTQKPLWSYRTKYPEWALEPHRRYMEMAVKEAG-----KCGPTKTAFSVGAVLVHGTQVLATGYSRELPGNTHAEQCALIKYSQLHPNCPTIVPMGTVLYTTMEPCSFRLSGNEPCCDRILATQGAIGTVFVGVMEPDTFVKNNTSLNKLESHGVNYIQIPGYEEECTIIAFKGHDNSDDKA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : : . : . . : ::. ***: **:* : :: * ** ...::.:* *** *. : * : :* . . ::..*:: : ***** ** :*: :: : :::*::**:*:**** **:*.**: :* :: ::. :***: ***::::.:: : .: :: *:: ***:.** * ** * .: : *. ::.: * .* . * *:::. * *:* *:***** ********:**.** ***:*. :** .:.* : : : ::. : : : . . . : . :* * : : .* .:* : : . . ", "identical_positions": 92, "similar_positions": 126, "identity": "11.26%" }, { "cls_id": "homologset.agr.SGD:S000005429", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JZ79-1", "uniprot_id": "SIR1_RAT", "id": "A0A0G2JZ79-1", "name": "NAD-dependent protein deacetylase sirtuin-1", "aln": "-----MADEAALALQAGGSPSAA-AAMEAASQPADEPLRKRPRRDGPGLGRSPGEPSAAAAAAAAAAGCEAASAAAPAALWREAAGAAAASA-EREAPATAAAGDGDNGPGLR---REPRAADDFDDDEGEEEDE-AAAAAAAAIGYRDNLLLADEIITNGFHSCESDDDDRASHASSSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIP--PPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQR--IIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEP-------------------------LAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGG---EYAKLCCNPVKLSEITEKPPRTQK----------------ELVHLSELPPTPLHISEDS----------------------SSPERTVPQDSSVIATLVDQTIKNKVDDLEVSEPKSCVEEKSQEVQTYRNVESIN--------VENPDFKAVGSSTGDKNERTSVAETVRKCWPNRLAKEQISKRLD-GNQYLFVPPNRYIFHGAEVYSD----SEDDALSSSSCGSNSDSG-------------------TCQSPSLEEPLEDESEIEEFYNGLEDDADRPECAGGS--GADGGDQEAVNEAIAMKQELTDVNCTPDKSEHY--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q923E4-1", "uniprot_id": "SIR1_MOUSE", "id": "Q923E4-1", "name": "NAD-dependent protein deacetylase sirtuin-1", "aln": "-----MADEVALALQAAGSPSAA-AAMEAASQPADEPLRKRPRRDGPGLGRSPGEP--SAAVAPAAAGCEAASAAAPAALWREAAG-AAASA-EREAPATAVAGDGDNGSGLR---REPRAADDFDDDEGEEEDEAAAAAAAAAIGYRDNLLLTDGLLTNGFHSCESDDDDRTSHASSSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIP--PPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQR--ILQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEP-------------------------LAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGG---EYAKLCCNPVKLSEITEKPPRPQK----------------ELVHLSELPPTPLHISEDS----------------------SSPERTVPQDSSVIATLVDQATNNNVNDLEVSES-SCVEEKPQEVQTSRNVENIN--------VENPDFKAVGSSTADKNERTSVAETVRKCWPNRLAKEQISKRLE-GNQYLFVPPNRYIFHGAEVYSD----SEDDVLSSSSCGSNSDSG-------------------TCQSPSLEEPLEDESEIEEFYNGLEDDTERPECAGGSGFGADGGDQEVVNEAIATRQELTDVNYPSDKS-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EB6-1", "uniprot_id": "SIR1_HUMAN", "id": "Q96EB6-1", "name": "NAD-dependent protein deacetylase sirtuin-1", "aln": "-----MADEAALALQPGGSPSAAGADREAASSPAGEPLRKRPRRDGPGLERSPGEPGGAAPEREVPAAARGCPGAAAAALWREAEAEAAAAGGEQEAQATAAAGEGDNGPGLQGPSREPPLADNLYDEDDDDEGEEEEEAAAAAIGYRDNLLFGDEIITNGFHSCESDEEDRASHASSSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIP--PPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQR--IIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEP-------------------------LAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGG---EYAKLCCNPVKLSEITEKPPRTQK----------------ELAYLSELPPTPLHVSEDS----------------------SSPERTSPPDSSVIVTLLDQAAKSN-DDLDVSESKGCMEEKPQEVQTSRNVESIAE------QMENPDLKNVGSSTGEKNERTSVAGTVRKCWPNRVAKEQISRRLD-GNQYLFLPPNRYIFHGAEVYSD----SEDDVLSSSSCGSNSDSG-------------------TCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGAGFGTDGDDQEAINEAISVKQEVTDMNYPSNKS-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VK34-1", "uniprot_id": "SIRT1_DROME", "id": "Q9VK34-1", "name": "NAD-dependent histone deacetylase sirtuin-1", "aln": "----MMENYEEIRLGHIRSKDLG-------NQVPDTTQFYPPTKFDFG----------AEILASTSTEAEAEAEATATTTEPATSELAGKANGEIKTKTLAAREEQEIGANLEHKTKNPTKSMGEDEDDEEEEEEDDEEEEE-----------DDEEGITGTSNEDEDSSSNCSSSVEPDWKLR-------WLQREFYTGRVPRQVIASIMPHFATGLAGDTDDSVLWDYLAHLLNEPKRRNKLASVNTFDDVISLVKKSQKIIVLTGAGVSVSCGIPDFRSTNGIYARLAHDFPDLPDPQAMFDINYFKRDPRPFYKFAREIYPGEFQPSPCHRFIKMLETKGKLLRNYTQNIDTLERVAGIQR--VIECHGSFSTASCTKCRFKCNADALRADIFAQRIPVCPQCQPNKEQSVDASVAVTEEELRQ------LVENGIMKPDIVFFGEGLPDEYHTVMATDKDVCDLLIVIGSSLKVRPVAHIPSSIPATVPQILINREQLHHLKFDVELLGDSDVIINQICHRLSDNDDCWRQLCCDESVLTESKELMPPEHSNHHLHHHLLHHRHCSSESERQSQLDTDTQSIKSNSSADYILGSAGTCSDSGFESSTFSCGKRSTAAEAAAIERIKTDILVELNETTALSCDRLGLEGPQTTVESYRHLSIDSSKDSGIEQCDNEATPSYVRPSNLVQETKTVAPSLTPIPQQRGKRQTAAERLQPGTFYSHTNNYSYVFPGAQVFWDNDYSDDDDEEEERSHNRHSDLFGNVGHNYKDDDEDACDLNAVPLSPLLPPSLEAHIVTDIVNGSNEPLPNSSPGQKRTACIIEQQPTPAIETEIPPLKKRRPSEENKQQTQIERSEESPPPGQLAAV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53685-1", "uniprot_id": "HST1_YEAST", "id": "P53685-1", "name": "NAD-dependent protein deacetylase HST1", "aln": "MNILLMQRIVSFILVVSQGRYFH-------VGELTMTMLKRPQ--------------------EEESDNNATKKLKTRLTYPCILGKDKVTG---KFIFPAITKDDVMNARLFLKDNDLKTFLEYFLPVEVNSIYIYFMIKLLG------FDVKDKELFMALNSNITSNKERSSAELSS-----------------IHAKAEDEDELTDPLEKKHA-------VKLIKDLQKAINKVLSTRLRLPNFNTIDHFTATLRNAKKILVLTGAGVSTSLGIPDFRSSEGFYSKIRHLG--LEDPQDVFNLDIFLQDPSVFYNIAHMVLPPENMYSPLHSFIKMLQDKGKLLRNYTQNIDNLESYAGIDPDKLVQCHGSFATASCVTCHWQIPGEKIFENIRNLELPLCPYCYQKRKQYFPMSNGNNTVQTNINFNSPILKSYGVLKPDMTFFGEALPSRFHKTIRKDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQILINRDMVTHAEFDLNLLG--------FCDDVAS---LVAKKCHWDIPHKKWQDLKKIDYN--------------------CTEIDKGTYKIKKQP--------------------------RKKQQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * . . * : .. . : : * : .. * .: :. * . . ..... * .. : . : . : . . : : : . * : ..**::. :::.:**:********.* ******* :*:*::: * *** :*::: * :** *:::*: : * : * * ** : : :************.** ***: :::*****:**** *::: : : :* :* ** * .. .::**::.**** **..:* .: * **** **:**** **: * . :* ********: : * .**::*** :*. :.. : * .: : . ::: . :..:. *. ", "identical_positions": 118, "similar_positions": 123, "identity": "13.56%" }, { "cls_id": "homologset.agr.SGD:S000005430", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYL9-1", "uniprot_id": "NUF2_RAT", "id": "Q6AYL9-1", "name": "Kinetochore protein Nuf2", "aln": "--METLSFPRYNIAEIVVHIRNKLLTGADGKNLSKSDFLPNPKPEVLYMIYMRALQLVYGVRLEHFYMMPVN------IEVMYPHIMEGFLPVSNLFFHLDSFMPICRVNDFEIADILYPKANRTSRFLSGIINFIHFRETCLEKYEEFLLQNKSSVDKIQQLSNAHQEALMKLEKLNSVPVEEQEEFKQLKDDIQELQHLLNQDFRQKTTLLQERYTKMKSDFSEKTKHVNELKLSVVSLKEVQDSLKSKIVDSPEKLKNYKEKMKDTVQKLRSAREEVMEKYDIYRDSVDCLPSCQLEVQLYQKKSQDLADNREKLSSILKESLNLEGQIDSDSSELKKLKTEENSLIRLMTLKKERLATMQFKINKKQEDVKQYKRTMIEDCNKVQEKRDAVCEQVTAINQDIHKIKSGIQQLRDAEKREKLKSQEILVDLKSALEKYHEGIEKTTEECCTRIGGKTAELKRRMFKMPP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99P69-1", "uniprot_id": "NUF2_MOUSE", "id": "Q99P69-1", "name": "Kinetochore protein Nuf2", "aln": "--METLSFPRYNVAELVVHIRNKLLTGADGKNLSKSDFLPNPKSDVLYMIYMKALQLVYGVRLEHFYMMPMN------IEVTYPHLMEGFLPVRSLFFYMDSFMPICRVNDFEIVDILNPRTNRTSRFLSGIINFIHFRETCLEKCEEFLLQNKSSMVRMQQLSNVHQEALMKLEKLNTVPAEEREEFKQFMDDIQELQHLLNEEFRQKTTLLQEEYAKMKSDISEKTKHLNEQKLSLVSLKEVEDNLKSKIVDSPEKLKNYKDKMKGTVQKLRSAREKVMEQYDIYRDSVDCLPSCQLEVQLYQKKSQDLADNREKLSSLLKESLNLEDQIESDSSELKKLKTEENSLIRMTTVKKEKLATARFKINKKQEDVKHYKQAMIEDCNKVQEKRDAVCEQVTTVNQEIHKIKSAIQQLRDTKKREILKSQEIFVNLKSALEKYHEGIEKVAEERSAKLEEKTAELKKRMVRMV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZD4-1", "uniprot_id": "NUF2_HUMAN", "id": "Q9BZD4-1", "name": "Kinetochore protein Nuf2", "aln": "--METLSFPRYNVAEIVIHIRNKILTGADGKNLTKNDLYPNPKPEVLHMIYMRALQIVYGIRLEHFYMMPVN------SEVMYPHLMEGFLPFSNLVTHLDSFLPICRVNDFETADILCPKAKRTSRFLSGIINFIHFREACRETYMEFLWQYKSSADKMQQLNAAHQEALMKLERLDSVPVEEQEEFKQLSDGIQELQQSLNQDFHQKTIVLQEGNSQKKSNISEKTKRLNELKLSVVSLKEIQESLKTKIVDSPEKLKNYKEKMKDTVQKLKNARQEVVEKYEIYGDSVDCLPSCQLEVQLYQKKIQDLSDNREKLASILKESLNLEDQIESDESELKKLKTEENSFKRLMIVKKEKLATAQFKINKKHEDVKQYKRTVIEDCNKVQEKRGAVYERVTTINQEIQKIKLGIQQLKDAAEREKLKSQEIFLNLKTALEKYHDGIEKAAEDSYAKIDEKTAELKRKMFKMST", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZW63-1", "uniprot_id": "NUF2_DANRE", "id": "Q7ZW63-1", "name": "Kinetochore protein Nuf2", "aln": "--MSENTFPVYKVDVIVQFYRTEVLTGQESKHFTKNDLTPTPKPESVQRLYMRILQLLFRFRPECHYTVPLS------ENIQYPMLYESFAPIMSVYMRMCQFLPVCRVYDFSLSDLLNPKTKRTITILSAIQNFLHFRKQRLEITAAHQQSFRADMDRLQAYTREIKEAEKKIEKLTTIPPEQQAEAKELASALAELSTNTQHEYQDVSAIN-EKVAQFKTEIAELSQKLTQRKVEVATLKDEISKLKSQIVESPEELKNEMERMRETAKNIKMSKELADERLVELQMLVQCASQVEAEIQILLKQLQDLQSSMSKTKQRKEEVQSLEVMNESLQKELKSLSSEEAQLKRALTMKLDKESKQQIRRQKKKEVKDQQVKNIYGQYDKMHQKRQEIVKKIEECNRETKQFKEKMQALRENCNQRTQKAQEIYERLLTTLEQYHKRIEKILVETNADALKMKSHF---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P33895-1", "uniprot_id": "NUF2_YEAST", "id": "P33895-1", "name": "Kinetochore protein NUF2", "aln": "MSRNQDVFPILDLQELVICLQSCDFALATQENISR------PTSDYMVTLYKQIIENFMGISVESLLNSSNQETGDGHLQEENENIYLDTLNVLVLNKICFKFFENIGVQDFNMTDLYKPEAQRTQRLLSAVVNYARFREERMFDCNSFILQMESLLGQLRSKFDDYNLIQQQLKQYEDVDGDNIPDEQELQK-LEEQNKELEIQLKKLTKIQETLSIDYNDYKISKQSIFKDLEALSFQIVELESNRDKLIKISNTDMEELSEGIKELNDLLIQRKKTLDDLTAQQKNLQDTVTTFETIISELYDVLRIISSEVQESNRTETELVGLKQNLIN--NKLKLMNVLETGIMYKLEILQEQLDLQLKNLEKLSQDTK--------EESRLNDTKLMDLQIKYENEIKPKIDKTDIFIQEELISGKINKLNDEIKQLQKDFEVEVKEIEIEYSLLSGHINKYMNEMLEYMQ----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ** .: :* :. :: ::::: *..: : :* : :: . . * . . : : . . : .*: * **. *: *.::** :**.: *: :**: . . .: ::: : :::: : :: : ::: . : * . : : :. : : . : . . ..: : : : .. .. * * .::: : :: . : :: : : . : :. . : : .. .: * .*: . .:** :. * : : :: . :* : . : .::::.: : : . : * : .: . . * :: * . :* . ** .: ", "identical_positions": 34, "similar_positions": 148, "identity": "7.2%" }, { "cls_id": "homologset.agr.SGD:S000005432", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJQ7-1", "uniprot_id": "SDHF2_RAT", "id": "Q5RJQ7-1", "name": "Succinate dehydrogenase assembly factor 2, mitochondrial", "aln": "MAVVTLIPT--LARVLSKHSLLSPLLSVTSFRRFYRGDSPTD-----------SQKDMIEIPLPPWQERTDESIETKRARLLYESRKRGMLENCILLSLFAKEYLHNMTEKQLNLYDRLINEPSNDWDIYYWATE---AKPAPEIFEN-EVMELLREFTKNKNKEQRLRAPDLEYLFEKPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C6I2-1", "uniprot_id": "SDHF2_MOUSE", "id": "Q8C6I2-1", "name": "Succinate dehydrogenase assembly factor 2, mitochondrial", "aln": "MAVVTLIPT--LARALSKHSLLSPLPSVTSFRRFYRGDSPTD-----------SQKDMIEIPLPPWQERTDESIETKRARLLYESRKRGMLENCILLSLFAKEYLHNMTEKQLNLYDRLINEPSNDWDIYYWATE---AKPAPEIFEN-EVMELLREFAKNKNKEQRLRAPDLEYLFEKPH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NX18-1", "uniprot_id": "SDHF2_HUMAN", "id": "Q9NX18-1", "name": "Succinate dehydrogenase assembly factor 2, mitochondrial", "aln": "MAVSTVFSTSSLMLALSRHSLLSPLLSVTSFRRFYRGDSPTD-----------SQKDMIEIPLPPWQERTDESIETKRARLLYESRKRGMLENCILLSLFAKEHLQHMTEKQLNLYDRLINEPSNDWDIYYWATE---AKPAPEIFEN-EVMALLRDFAKNKNKEQRLRAPDLEYLFEKPR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KP74-1", "uniprot_id": "SDHF2_DANRE", "id": "A3KP74-1", "name": "Succinate dehydrogenase assembly factor 2, mitochondrial", "aln": "MFSANIARK--VVCSVCRASLR-PTVCPVVYRG-YRGDAP--------------EPTILEIPLPPWQERAGEALDIKRKRLLYESRKRGMLENCILLSLFAKQYLNTMSESQLKQYDRLINEPSNDWDIYYWATD---TQPTPEVYQG-EVMDMLKEFTKNRDMEQRLDAPNLEYLDKSS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q4V5I9-1", "uniprot_id": "SDF2A_DROME", "id": "Q4V5I9-1", "name": "Succinate dehydrogenase assembly factor 2-A, mitochondrial", "aln": "-----MLRQLRLTMDISGWIFLPWR---RSMSNMKDSPPPPPPLASTFNDVIVDYEDPDYLPLPEYPVRPNEPLETRKQRLLYQSRKRGMLENDLLLSTFAAKHLQNFSAEQTAQYDQLINGVSNDWDIYYWATE---VKPTPKEYDT-EIMGLLKEHVKNAERVTRLRQPDLNI------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z897-1", "uniprot_id": "SDF2B_DROME", "id": "A1Z897-1", "name": "Succinate dehydrogenase assembly factor 2-B, mitochondrial", "aln": "-----MLRQF-IVSTVGRRLQLPMMAQSRLASNLDKTEYTTP-------GEIVDYDDPPHLPVPEYPVRPDEPLETRKQRLLYQSRKRGMLENDLLLSTFVAKHLKDFNAEQTAEYDQLINGVSNDWDIFYWATD---TKPTPPQFDT-EIMRLLKEHVKNHEKVQRIRQPDL--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08230-1", "uniprot_id": "SDHF2_YEAST", "id": "Q08230-1", "name": "Succinate dehydrogenase assembly factor 2, mitochondrial", "aln": "--MHNMFPALTKTLSLQGYKIINSQTGSAAWSCGRRWFSSDK----------DDHDDVVTRIKIAPIKRTNEPLDKKRARLIYQSRKRGILETDLLLSGFAAKYLKKMNEEELEEYDSLLN--ELDWDIYYWATKNFKTSPLPDKWANSKLLKQLQEFSENKEKE-ILSMPDLSKYQ----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . *..*.:: :: **:*:*****:**. :*** *. ::*: :. .: ** *:* . ****:****. ..* * : ::: *::. :* : : *:* ", "identical_positions": 35, "similar_positions": 40, "identity": "19.34%" }, { "cls_id": "homologset.agr.SGD:S000005433", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAF5-1", "uniprot_id": "F1MAF5_RAT", "id": "F1MAF5-1", "name": "PCI domain-containing protein 2", "aln": "--MAHITINQYLQQVYEAIDTRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPP-YDEMFAAHLRCTYAVGN--HDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRVFANNADQQLVKKGKSKVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWG----MLFLVNQLFKIYFKINKLHLCKPLIRAIDSS---NLKDDYSTAQRVTYKYYVGRKAMFDSDFKQAEEYLSFAFEHCH------RSSQKNKRMILIYLLPVKMLLGHMPTI----ELLRKYHLMQFSEVTRAVSEGNLLLLNEALAKHE-TFFIRCGIFLILEKLKIITYRNLFKKVY---------------LLLKTHQLSLDAFLVALKFMHVEDVD----IDEVQCILANLIHMGHIKGYISHQHQKLVVSK----QNPFPPLSTVC------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFV2-1", "uniprot_id": "PCID2_MOUSE", "id": "Q8BFV2-1", "name": "PCI domain-containing protein 2", "aln": "--MAHITINQYLQQVYEAIDTRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPP-YDEMFAAHLRCTYAVGN--HDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRIFANNADQQLVKKGKSKVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWG----MLFLVNQLFKIYFKINKLHLCKPLIRAIDSS---NLKDDYSTAQRITYKYYVGRKAMFDSDFKQAEEYLSFAFEHCH------RSSQKNKRMILIYLLPVKMLLGHMPTI----ELLRKYHLMQFSEVTKAVSEGNLLLLNEALAKHE-TFFIRCGIFLILEKLKIITYRNLFKKVY---------------LLLKTHQLSLDAFLVALKFMHVEDVD----IDEVQCILANLIYMGHIKGYISHQHQKLVVSK----QNPFPPLSTVC------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JVF3-1", "uniprot_id": "PCID2_HUMAN", "id": "Q5JVF3-1", "name": "PCI domain-containing protein 2", "aln": "--MAHITINQYLQQVYEAIDSRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPP-YDEMFAAHLRCTYAVGN--HDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRVFANNADQQLVKKGKSKVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWG----MLFLVNQLFKIYFKINKLHLCKPLIRAIDSS---NLKDDYSTAQRVTYKYYVGRKAMFDSDFKQAEEYLSFAFEHCH------RSSQKNKRMILIYLLPVKMLLGHMPTV----ELLKKYHLMQFAEVTRAVSEGNLLLLHEALAKHE-AFFIRCGIFLILEKLKIITYRNLFKKVY---------------LLLKTHQLSLDAFLVALKFMQVEDVD----IDEVQCILANLIYMGHVKGYISHQHQKLVVSK----QNPFPPLSTVC------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5U3P0-1", "uniprot_id": "PCID2_DANRE", "id": "Q5U3P0-1", "name": "PCI domain-containing protein 2", "aln": "--MAHITLNQYLQQVLEAIDSRDGSFCAEMMSFKHPHVANPRLQLSSPEEKCQQLLEPP-YDEMVAAHLRCTFAVSN--HDFVEAYKCQTVVVQSFLKAFQAHKEENWALPIMFAVTLDLRIFANNAEQHLQQKGKGKVGDMLEKAAEQLMSCFRVCASDNRAGIDDSKKWG----MLFLINQLFKIYFKINKLHLCKPLIRAIDSS---NLKDEYTMAQRVTYKYYVGRKAMFDSDFKPAEECLSFSFTHCH------RSCQRNKRLILIYLLPVKMLLGHMPTH----QLLKKYDLMQFADVTRAVSEGNLLLLNAALVKHE-TFFIRCGIFLILEKLKIITYRNLFKKVY---------------HLLRTHQLPLAAFLVSLQMTKVEDVD----IDEVQCILANLIYMGHIKGYISHQHQKLVVSK----QNPFPPLSSIS------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTL1-1", "uniprot_id": "PCID2_DROME", "id": "Q9VTL1-1", "name": "PCI domain-containing protein 2 homolog", "aln": "---MFGTVNNYLSGVLHAAQDLDGESLATYLSLRDVHVQNHNLYIAQPEKLVDRFLKPP-LDEVVSAHLKVLYHLAQEPPGYMEAYTQQSAACGAVVRLLQQLKDENWCLPLMYRVCLDLRYLAQACEKHCQG---FTPGHVLEKAADCIMACFRVCAADGRASEEDTKRLG----MMNLVNQLFKIYFRINKLHLCKPLIRAIDNC---IFKDSFPLPEQITYKYFVGRRAMFDSNYQAAVQYLSYAFSNCP------DRFASNKRLILIYLVPVKMLLGYLPSK----SLLQRYDLLLFLDLAMAMKAGNVNRFDEIVRDQE-LVLIRSGIYLLVEKLKFLVYRNLFKKVF---------------VIRKSHQLDMGDFLSALHFVGLTDVS----LDETHCIVANLIYDGKIKGYISHAHNKLVVSK----QNPFPSVSL--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08231-1", "uniprot_id": "THP1_YEAST", "id": "Q08231-1", "name": "Nuclear mRNA export protein THP1", "aln": "MDMANQLLDELAHGNFSHLTLNLSQNGREIAILQKQLTGFDDKQLETFVEQHPAMPNDTRFKIMCTSFLNYARDVDP--WSAWSSSDLIFEFYQCLINCLINDNAPHIEMLIPVATRETEFIINLAGKLDSFHLQLHTRSHQFLSHISSILSRLFNSIKPPRGNASSTNIPGKQRILLYLVNKLNNIYFRIESPQLCSNIFKNFQPKSMLAHFNEYQLDQQIEYRYLLGRYYLLNSQVHNAFVQFNEAFQSLLNLPLTNQAITRNGTRILNYMIPTGLILGKMVKWGPLRPFLSQETIDNWSVLYKHVRYGNIQGVSLWLRQNERHLCARQLLIVLLEKLPMVTYRNLIKTVIKSWTTEWGQNKLPYSLIERVLQLSIGPTFEDPGAQEITIYNGIHSPKNVENVLVTLINLGLLRANCFPQLQLCVVKKTTMIQEIVPPVNERITKMFPAHSHVLW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: . ::. . : : . : . . : ::.*. : . .: ..:. : : : : : . : . . . .. : . . ::: : . *.. ..:: * :: *:*:* :***:*:. :**. ::: :: :.: ::: *:* :** :::*: : * :. :* * ** *::*. ::** : . :* : : : : : **: . : .:* . * : :::*** ::.****:*.* : : ** : : : . .:.. ::..** * ::. : **.* *: .*.:. ", "identical_positions": 50, "similar_positions": 136, "identity": "10.94%" }, { "cls_id": "homologset.agr.SGD:S000005434", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R1K1-1", "uniprot_id": "UBAC2_MOUSE", "id": "Q8R1K1-1", "name": "Ubiquitin-associated domain-containing protein 2", "aln": "-MFTSTGSSGLYKAPLSKSLLLVPSALSLLLTLLLPHCQKFFVYDLHAVKHDL-QIWRLICGRIICLDLKDAFCSGLLIYNFRIFERRYGSRKFASFLLGSWVLSALFDF---ILVEAVQYSLGVTVASNLPSGFLAPVFALFVPFHCSIPRVQVAQILGPLSITNKTLIYILGLQLFTSGSYIWIVAMSGLISGMCYDRKVLQVHQVLRIPGRMAEFFSWALEPIFSSSEPTSEARVGMGATVDIQRQQRMEQLDRQLMLSQFAQVRR---QRQQQGGMINWNRLFPPLRQRRNINYQDGPRSEQRASPPL--EVSEEQVARLMEMGFSRGDALEALRASNNDLNVATNFLLQH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LQF5-1", "uniprot_id": "F1LQF5_RAT", "id": "F1LQF5-1", "name": "Ubiquitin-associated domain-containing protein 2", "aln": "-MFTSTGSSGLYKAPLSKSLLLVPSTLSLLLTLLLPHCQKFFVYDLHAVKNDF-QIWRLICGRIICLDLKDAFCSGLLIYNFRIFERRFGSRKFASFLLGSWVLSALFDF---ILVEAVQYLLGVTVASNLPSGFLAPVFALFVPFHCSIPRVQVAQILGPLSITNKTLIYILGLQLFTSGSYIWIVAMSGLISGMCYDRRVLQVHQVLCIPSRLAQFFSWALEPIFSSSEPTSEARVGMGATVDIQRQQRMEQLDRQLMLSQFAQVRR---QRQQQGGMINWNRLFPPLRQRRNINYQEGPRSEQRAPPPL--EVSEEQVARLMEMGFSRGDALEALRASNNDLNVATNFLLQH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NBM4-1", "uniprot_id": "UBAC2_HUMAN", "id": "Q8NBM4-1", "name": "Ubiquitin-associated domain-containing protein 2", "aln": "-MFTSTGSSGLYKAPLSKSLLLVPSALSLLLALLLPHCQKLFVYDLHAVKNDF-QIWRLICGRIICLDLKDTFCSSLLIYNFRIFERRYGSRKFASFLLGSWVLSALFDF---LLIEAMQYFFGITAASNLPSGFLAPVFALFVPFYCSIPRVQVAQILGPLSITNKTLIYILGLQLFTSGSYIWIVAISGLMSGLCYDSKMFQVHQVLCIPSWMAKFFSWTLEPIFSSSEPTSEARIGMGATLDIQRQQRMELLDRQLMFSQFAQGRR---QRQQQGGMINWNRLFPPLRQRQNVNYQGGRQSEP-AAPPL--EVSEEQVARLMEMGFSRGDALEALRASNNDLNVATNFLLQH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NBJ1-1", "uniprot_id": "A0A8M1NBJ1_DANRE", "id": "A0A8M1NBJ1-1", "name": "", "aln": "MMFTSTGSWGLYKAPLSKSLLLLPTVLTVLLTVLLPQYQDLFIYNIQAIRQGK-QFWRLVSGRLFCLDLKDTFCSSLLIYNFRIFERRFGSHKFASFLFGAWVLSAFVDL---LLTEALRFTFELKVD-VLPAGLLGPVFALFVPFYRSIPRVHVTQLLGHFSITNKSLTYIVGAQLLTSSAYMWVVACSGLIAGMLYYSNKLAVQKFLRVPGWAARCGSVILEPIFSDSEPTAEAPLGMGATLDIQRQQRMDMLDQQLLLSQLAHLRRNAQQQQAQTGLLNWNRFFPTLRHRGQNRPHEGPQQPSYTQPTENPAVTEEQVARLMEMGFSRMDAQEALRASNNDINIATNFLLQH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08232-1", "uniprot_id": "DSC2_YEAST", "id": "Q08232-1", "name": "DSC E3 ubiquitin ligase complex subunit 2", "aln": "--MSMEPPVGLTAMPVTK--LAMITTLVVPLVASIASYKHIFLLQYDPFLQTYHQYYRLLIFQFCAINESDTVILALIWYLFRHLERLLGSHKYLTLIVLSWAYTTLGIWGLNLIWNAFIGQYKWLQWNNFSTGSLPIVLSLVHFYKEYTPQIYEWNIR--LLGPRGGASSHNDNKREDKSAVEWKINDQFLLNGLILLLILNQG-----FAGILCGFISWMCGIFIDKGLLPGLDHWRIPFVSYFISQGPPTRANVAIAANAAT-------NTAAARATVEAATAATGNGNTGNSGPTSLPLRGSSTTPTN---------------TSSAGDDEPGADEPARPLGVQFLDTFRR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . ** *::* * : :.* : *. :. :.:*: : ... : * :**: :: .:: .*:. .*: * ** :** **:*: :::. :*. ::: :: :*. :.:* * *::*. : *:: :: : .. . : ..: * : . *: *: ... . * ::... .. : . : * : : . : : . :: . : : : *. * * . . . :.: :::", "identical_positions": 36, "similar_positions": 108, "identity": "10.14%" }, { "cls_id": "homologset.agr.SGD:S000005435", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IPV3-1", "uniprot_id": "Q8IPV3_DROME", "id": "Q8IPV3-1", "name": "ABC transporter domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNQYSWKQFLENN-----NLLGTAGAGQLKAQIVPAQPKT--------------LQHLPKRPAVDLAFHNLTYRVKEGNR---------------------------------SNAKTILKGVSGRLRSGELTAIMGPSGAGKSTLLNILSGYKTSS------IEGSVTMNGAERNLSAFRKLSAYIMQDN-QLHGNLTVQEAMTVATNLKLS-KKFSKPEKHSMIDDILLTLSLSEHRYTMT-----RNLSGGQKKRLSIALELVSNPPIMFFDEPTSGLDSSTCFQCIHLLKMLAAG-GRTVICTIHQPSARLFEMFDQLYTLA-DGQCVYQGSTKQLVPFLSTLNLECPSYHNPASYVIEVSCGEHG-DHTRKLVDAIDNGKRDVRSSADYAGLKAR----NDLVK-----VQNLKAILDKND-ASSVSGRKYEDNLTLNN-------------------GLLNGMVNDIVKEGNVSSALVTTNERGDAMIDVEKSVN-CTTALLT---EEITSPER--YPTSQFHQFWVVLKRTLLFSYRDWTLMYLRLFAHLLVGFLIGALYYDIGNDGAK--VLSNLGFLFFNMLFLMYTSMTITILSFPLEMPVLLKENFNRWYSLKSYYLAISVADLPFQAIFCVIYVSIVYYFTSQPWELFRFSMFLSACLLISFVAQSVGLVVGAAMN-VQNGVFLAPVMSVP-FLLFSGFFVSFDA---IPVYLRWITYLSYIRYGFEGTALATYGYG----REKLRCFQT--YCHFKSPITTLEELDMVNAN-FTLDIVALIVIFVVLRISAYLFLRWKLKTVR-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQY4-1", "uniprot_id": "Q9VQY4_DROME", "id": "Q9VQY4-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNELQASSVPLVDKCSSHAVILPAAKSPNRVSDSAATTAPNAVLYTSGNMSLSTLSTGSGNPNPNPNASTNSRQEPVPLLSQLKLTNDLKQNSHGSQNNLCNGGLGSNNHALAPKVANNSGGSPNGQKKGTIALSHLPQRPPVDIEFCDISYSVTDSHR---------------------------------RGFKTILKSVSGKFRNGEITAIMGPSGAGKSTLMNILAGYKTAQ------LSGSVLINSKERNLRRFRKLSCYIMQDD-VLIANLTVREAMMVAANLKLG-KNMISYAKVVVVEEILETIGLKESVNTLT-----CNLSGGQRKRLSIALELVNNPPVMFFDEPTSGLDSSTCFQLISLLRSLARG-GRTIVCTIHQPSARLFEKFDHLYLLA-QGQCVYEGRVKGLVPYLSSLGYECPSYHNPADYVLEVASGEYG-DAVPKLVDAVKSGACKKYAHKDYVLTLAQKGCNNDIIKGSGSGAENAMAILTLEDEKPPLEDRQLEPSIPVDDPAELKPPKLETQQSQNSDCSVVNMPTNAVDDSCSFSSSKGTQNAVGGSGSGGPSAVVGCMTSLLDSHESVVTLPNKTGFPTSGWTQFWILLKRSFRTILRDKMLTHMRLFSHVIVGAIIGMIYYDVGNEASK--IMSNAGCIFFVSLFTTFTAMMPTILTFPTEMSVFVREHLNYWYSLKAFYFAKTIADMPFQIVFSSVYVLVVYYLTSQPMELERVSMFVLICVLNSLVAQSLGLLIGAGMN-IETGVFLGPVTTIP-TILFSGFFVNFDT---IPGYLQWVTYVSYVRYGFEGAMVAIYGMD----RAKMQCNQM--YCHYRVPKKFLEEMSMDNAL-FWVDAVALIGIFFALRIIAYFVLRWKLHMIR-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VL61-1", "uniprot_id": "Q9VL61_DROME", "id": "Q9VL61-1", "name": "ABC transporter domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATPREQFLFGSDNGVAGLGLGIEIGEVTSSRVYNSTTVPVGNSGGWRNAQSS----VTPPPIPTPPQVN-------YTNGNEPSKQPPLEPVVEEEVHFDTD-------ALNNLPAREPVDMEFKELSLTVKLGFN---------------------------------RGSKEILHNVCGKFPGSQLIAIMGPSGAGKSTLLDALSGFKTTG------VDGSILLNGRRRDLPSFRRMSCYITQDD-RLQPLLTVNENMHIAADLKLG-QTVSYEEKESRIEDILLLLGLYNHDQTLT-----MRLSGGQKKRLSIAMELINNPTVMFLDEPTTGLDSSSCTKVLELLKKLTSQ-GRTIICTIHQPTAKLFQIFDQVYVLS-AGNCVYQGSTQKLVPFLQSVDLPCPMYHNPADYIIELACGEYGYDKVDTLKLATENGSCLTWFHNPSAVLRAE-------------------VLMRKYPIPKKTKSRSLED--------------------------------------------------------------------------------------TSYSNQCSVLLRRGFIKAKRDTTMTHLRIGVNIAVAALFGAMYDHTGREGSR--VLDNYNLLFAILMHHSMTTMMLTVLTFPMDISILIKEHFNRWYSLKAYYTAMTLVDLPISIISCFFFTVIVYLWSYQPMEWIRFFMFFSISLLTVFVGHSFGLMIGAWFD-VVNGTFLAPVLTIP-MMMFAGFGVTLRD---LPSYLRWGSHISYLRYGLEGFISAIYGLD----RGTLACEEAP-YCHYRYPKKFLEEITMRGDQ-FWNDVIALGVMILVFRFVSYVVLKAKIKSIR-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PBX3-1", "uniprot_id": "M9PBX3_DROME", "id": "M9PBX3-1", "name": "ABC transporter domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKLTQEFALR------------------------------------------TMPDFATSSPFNIIFEDLYYRVEVGKD---------------------------------REKKSVLKGIKGTFKSGELTAIMGPSGAGKSSLMNILTGLTKSG------VSGKIEIG-------KARKLCGYIMQDD-HFFPYFTVEETMLMAATLKISNQCVSLKEKRTLIDYLLNSLKLTKTRQTKC-----SNLSGGQKKRLSIALELIDNPAVLFLDEPTTGLDSSSSFDTIQLLRGLANE-GRTIVCTIHQPSTNIYNLFNLVYVLS-AGRCTYQGTPQNTVMFLSSVGLECPPYHNPADFLLECANGDYG-DQTEALAEAAKD----IRWRYDQQLMQGED-----------ADAPSETQVAKFNESQSPGQVQVQVQKIEIQN-------------------------------------------------------------------MESSKDLTKHTYPPTEYMRLWLLIGRCHLQFFRDWTLTYLKLGIHVLCSILIGLFFGDSGSNATK--QISNVGMIMIHCVYLWYTTIMPGILRYPAEIEIIRKETFNNWYKLRTYYLATIITSTPVHIIFSTVYITIGYLMTDQPVEMDRFVKYLLSAVVVTICADGLGVFLGTVLN-PVNGTFVGAVSTSC-MLMFSGFLILLNH---IPAAMRFMAYISPLRYALENMVISLYGNQ----RGQLICPPTEFYCHFKNAVTVLRQFGMEDGD-FGHNILMILIQIAIFKVLSYFTLKHKIKTN------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPJ7-1", "uniprot_id": "Q9VPJ7_DROME", "id": "Q9VPJ7-1", "name": "ABC transporter domain-containing protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METASSVKGSTTSQISSLQYSSDINADSLEPDQSEDFQTVL----------------------------------------GLKYLPSWPAVNLQFSELCYVVPDQTN--------------------------------ASKTKTILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLAGFGAVC------ESGEILVNNSPRDMRVFRKMSRYIMQTD-VLDSQFTVLEMMILAANLKLG-KELNLKQKLEVIDEILGMLRLKDTLNTMA-----QKLSGGERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIALLKVLAAG-GRTVICSIHTPSAKIFEMLDAVYVLA-EGQCVYQGKGSNIVPFLKNFGLCCPITYNPADFIIEVACLEYGGSYHEPMVEAVGNGKVARWSP------------------------PAVEGETTTTKTDTTSGASSFYERDQ----------------------------------------------------------------------FDEEISPKLLEAKCSWWLQYKLLLVRMLIQMWRDKSYIKLKFYMNIVLALLVGSLYFGMGTSASK--ALFNFGFMFTIVIAYLYLPMMPVLLYFPTEINLLKREYNNQWYRLSSYYAAMVTSKLPSMFILAVIYLSIVYLMSSQPLEWFRFAMLFTIAFVTALTSDSFGLLISSRLS-LVNAMFMGPVLAVP-LILLSIYGIGYGGGTYISPLMRFLMHLSYLRHSMEGLVASLYDYG----RADTICEDTEIFCSFKKSKVLLAFLGFENMH-YLWSLSCLMSFYLLFTVAAYFMIRLRLKHSEVSPIFAYVIQLLTKYFNFTSYNY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTL3-1", "uniprot_id": "Q9VTL3_DROME", "id": "Q9VTL3-1", "name": "ABC transporter domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEQSQN---------------------------------------------------LLAKQSKNVEFQDVYYTVKERKNFWR-----------------------------VTGERRILNGVSGSFRNGQLSAIMGPSGAGKSSLLNAISGFRRDG------VTG---------NIKMKRDNACYITQDD-HHQTLLTVEELMNLACDLKL----KNRHKKAEIMTDILENLHLNHRRNVTA-----EKLSGGERKRLSIALELVDNPNIFFLDEPTSGLDEVTAAQCIRLLQAMAYE-GRTIVCTIHQPSATIYNYFDSIYVLA-KGQCVYQGSPRATIPFLRLAQLDCPRHYSPSDYIIELVDAEDG-HLVPALSDLTENGKLIYVVSQSEQLAPQQAVTTMFLEQQKRPFLPAFFAGSAASTDGTLIGGTSALLEQV----------------------------------------------------------------------KAFSKRLHTDRRDVCGFRQFIVLMRIMLLRITRARLALTIQLFHHLLCGLFFGLIFFQLGNQGAR--MFDHLKFCIGAVLMIVYTQVMVPILSYPAEVKLVKKETFNRWYTLTPYYMALTVSRLPVQVLLNITFMAVTYWMSGLPQQFWRFCIFVAVGLMISLVAEGMGLAIGATFS-ITNGSVVGPMLIAP-LMGLAVYGFDFAP--QVSGGMQLLMKFSYVRVGVVSLVLAVFGFQ----REELDCD--AIYCHFSDPRVLLKFLDVEKVS-MLHQFGLLAMLMLFFRVMMYISLRKRCYA-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E8U2-1", "uniprot_id": "Q0E8U2_DROME", "id": "Q0E8U2-1", "name": "ABC transporter domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADNAVQAQPNGLG-------------------------------------------PQKQKALELHFSQVSYSLKGATK----------------------------------GSTPIINEACGVFKSGRLTAILGPSGAGKSTLLNALAGFKLQG------VTGQFLLNGRPRDIMSFRKMSAYIAQNF-VMLNLLTVEETLRVSTDLKMP-SSTAAQEKQKIIDDIIDILQLQSCRRTLV-----KNLSGGEHKRLSIGIELVTNPPIMFFDEPTSGLDCVGSYQVICHLQRLAHD-GRIVVCVVHQPGSRLFQLFDDVLVLA-HGEVLYAGEQREMLPTFAQSGHICPQYYNPADFALEVCSQSSTTERCESLITQNKMMHSTASNVVKLQVDEET-------------------ALIDVHKDALDLSHLRGKEQVG-------------------------------------------------------------------------------------FWTQLSVLLRRHLRSMSRDMFAVQMRLVMHVVVALLLGVVYWQIGGDAQK--IVSNVSCLFFVILFVFAGNAMPSILLCMQDSAVFIREYYNGWYSLGAYYLSKVLADLPLQLTCPTMFISIGYFMTGQPPEFQRFAMCWALCVMTAFIGHFIGVIAGSLFT-MQLAIFLVPSATIP-FLLFSGFFIRLNE---LSWFLRPICDVSFFRYIFEGLMRAIYGYD----RGELECYATSNFCYYRTAEQFLKDFQMEGNE-FDWDMAVLGIFLILLLLAFFVTLNAVIRRALR----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9DBM0-1", "uniprot_id": "ABCG8_MOUSE", "id": "Q9DBM0-1", "name": "ATP-binding cassette sub-family G member 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEKTKEETQLWNGTVLQDASQGLQDSLFSS-ESDNSLYFTYSGQSNTLEVRDLTYQ----------------------------------------------VDIASQVPWFEQLAQFKIPWRSHSSQD--------------------------------SCELGIRNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKM----KSGQIWINGQPSTPQLVRKCVAHVRQHD-QLLPNLTVRETLAFIAQMRLP-RTFSQAQRDKRVEDVIAELRLRQCANTRVGNTYVRGVSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVTTLSRLAKG-NRLVLISLHQPRSDIFRLFDLVLLMT-SGTPIYLGAAQQMVQYFTSIGHPCPRYSNPADFYVDLTSIDRRSKEREVATVEKAQSLAALFLEKVQGFDDFLWK-------------AEAK---ELNTSTHTVSLTLTQDTDCG-----------------------------------------------------------------------------TAVELPGMIEQFSTLIRRQISNDFRDLPTLLIHGSEACLMSLIIGFLYYGHGAKQLS--FMDTAALLFMIGALIPFNVILDVVSKCHSERSMLYYELEDGLYTAGPYFFAKILGELPEHCAYVIIYAMPIYWLTNLRPVPELFLLHFLLVWLVVFCCRTMALAASAMLPTFHMSSFFCNALYNS-FYLTAGFMINLDN---LWIVPAWISKLSFLRWCFSGLMQIQFN-------GHLYTTQIGNFTFSILGDTMISAMDLNSHP-LYAIYLIVIGISYGFLFLYYLSLKLIKQKSIQDW--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58428-3", "uniprot_id": "ABCG8_RAT", "id": "P58428-3", "name": "ATP-binding cassette sub-family G member 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEKTKEETQLWNGTVLQDASS-LQDSVFSS-ESDNSLYFTYSGQSNTLEVRDLTYQGGTCL------------------------RSWGQEDPHMSLGLSESVDMASQVPWFEQLAQFKLPWRSRGSQD--------------------------------SWDLGIRNLSFKVRSGQMLAIIGSAGCGRATLLDVITGRDHGGKM----KSGQIWINGQPSTPQLIQKCVAHVRQQD-QLLPNLTVRETLTFIAQMRLP-KTFSQAQRDKRVEDVIAELRLRQCANTRVGNTYVRGVSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVRTLSRLAKG-NRLVLISLHQPRSDIFRLFDLVLLMT-SGTPIYLGVAQHMVQYFTSIGYPCPRYSNPADFYVDLTSIDRRSKEQEVATMEKARLLAALFLEKVQGFDDFLWK-------------AEAK---SLDTGTYAVSQTLTQDTNCG-----------------------------------------------------------------------------TAAELPGMIQQFTTLIRRQISNDFRDLPTLFIHGAEACLMSLIIGFLYYGHADKPLS--FMDMAALLFMIGALIPFNVILDVVSKCHSERSLLYYELEDGLYTAGPYFFAKVLGELPEHCAYVIIYGMPIYWLTNLRPGPELFLLHFMLLWLVVFCCRTMALAASAMLPTFHMSSFCCNALYNS-FYLTAGFMINLNN---LWIVPAWISKMSFLRWCFSGLMQIQFN-------GHIYTTQIGNLTFSVPGDAMVTAMDLNSHP-LYAIYLIVIGISCGFLSLYYLSLKFIKQKSIQDW--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H221-1", "uniprot_id": "ABCG8_HUMAN", "id": "Q9H221-1", "name": "ATP-binding cassette sub-family G member 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGKAAEERGLPKGATPQDTSG-LQDRLFSS-ESDNSLYFTYSGQPNTLEVRDLNYQ----------------------------------------------VDLASQVPWFEQLAQFKMPWTSPSCQN--------------------------------SCELGIQNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKI----KSGQIWINGQPSSPQLVRKCVAHVRQHN-QLLPNLTVRETLAFIAQMRLP-RTFSQAQRDKRVEDVIAELRLRQCADTRVGNMYVRGLSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVKTLSRLAKG-NRLVLISLHQPRSDIFRLFDLVLLMT-SGTPIYLGAAQHMVQYFTAIGYPCPRYSNPADFYVDLTSIDRRSREQELATREKAQSLAALFLEKVRDLDDFLWK-------------AETK---DLDEDTCVESSVTPLDTNCLP----------------------------------------------------------------------------SPTKMPGAVQQFTTLIRRQISNDFRDLPTLLIHGAEACLMSMTIGFLYFGHGSIQLS--FMDTAALLFMIGALIPFNVILDVISKCYSERAMLYYELEDGLYTTGPYFFAKILGELPEHCAYIIIYGMPTYWLANLRPGLQPFLLHFLLVWLVVFCCRIMALAAAALLPTFHMASFFSNALYNS-FYLAGGFMINLSS---LWTVPAWISKVSFLRWCFEGLMKIQFS-------RRTYKMPLGNLTIAVSGDKILSVMELDSYP-LYAIYLIVIGLSGGFMVLYYVSLRFIKQKPSQDW--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IGG8-1", "uniprot_id": "A0A0R4IGG8_DANRE", "id": "A0A0R4IGG8-1", "name": "ATP-binding cassette sub-family G member 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDDTVFHSGESFSSSYEKQIK-GRDILFSSPEEDSSLYFTYSGGRNELEVRNLNYE----------------------------------------------VDTAAQIPWYEKLSEFKMPWEMHSNK-----------------------------------QTVIKDLNLHVHSGQMLAVIGSSGCGKTSLLDIITCRDEGGSM----NSGEILINGKPSTRSLVKKSIAHVRQDD-RLLPHLTVRETLAFVAKLRLP-ANFSQKQRDQRVDDVIAELRLRQCAHTRVGNEYVRGVSGGERRRVSIAVQLLWNPGILILDEPTSGLDSFTAHNLVITLYRLARG-NRLVLLSVHQPRSDIFQLFDLVVLLS-SGSAVYCGQAKDMVSYFTTLGYPCPRYCNPSDYYVDLISIDRRTPEKEAQCLEKASMLAAQFLEKVKNNEDFMWK-------------SEVCGPPALEAPQSSVPSVSMKESVITVS--------------------------------------------------------------------------KQKDQLPGKVHQFTTLIRRQVFNDYRDLVTLVVHGLEALLMSLLIGFLYFGCTEEGLS--IQDTVALLYMIGALTPFAVVLDVIAKCHSERAMLYHELEDGMYSVTPYFFAKVLGELPEHCAFTLVYGVPIYWLAGLNVAPDRFLLNFLLVWLTVYCSRSMALFVAAALPTLQTSSFMGNALFTV-FYLTAGFVISLEN---MWMVASWFSYISFMRWGFEGMLQVQFR-------GTRIPITIGNLTVEFDGIKVVEMMKMNQYP-LFSCYLVLIAVSLVFILLYYLSLKFIKQKSSQDW--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q99PE7-1", "uniprot_id": "ABCG5_RAT", "id": "Q99PE7-1", "name": "ATP-binding cassette sub-family G member 5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSELPFLSPEGARGPHNNRGSQSSLEEGSVTGSEARHS-----------------------------------------LGVLNVSFSVSNRVGPWWNIKSCQQKWD----------------------------------RKILKDVSLYIESGQTMCILGSSGSGKTTLLDAISGRLRRTGT----LEGEVFVNGCELRRDQFQDCVSYLLQSD-VFLSSLTVRETLRYTAMLALR--SSSADFYDKKVEAVLTELSLSHVADQMIGNYNFGGISSGERRRVSIAAQLLQDPKVMMLDEPTTGLDCMTANHIVLLLVELARR-NRIVIVTIHQPRSELFHHFDKIAILT-YGELVFCGTPEEMLGFFNNCGYPCPEHSNPFDFYMDLTSVDTQSREREIETYKRVQMLESAFRQSDICHKILEN--------------------IERTRHLKTLPMVPFKTKNP-----------------------------------------------------------------------------------PGMFCKLGVLLRRVTRNLMRNKQVVIMRLVQNLIMGLFLIFYLLRVQNNMLKGAVQDRVGLLYQLVGATPYTGMLNAVNLFPMLRAVSDQESQDGLYQKWQMLLAYVLHALPFSIVATVIFSSVCYWTLGLYPEVARFGYFSAALLAPHLIGEFLTLVLLGMVQNPNIVNSIVALLSISGLLIGSGFIRNIEE---MPIPLKILGYFTFQKYCCEILVVNEFYGLNFTCGGSNTSVPNNPMCSMTQGIQFIEKTCPGATSRFTTNFLILYSFIPTLVILGMVVFKVRDYLISR----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08234-1", "uniprot_id": "YO075_YEAST", "id": "Q08234-1", "name": "Uncharacterized ABC transporter ATP-binding protein/permease YOL075C", "aln": "MSQQENGDVATELIENRLSFSRIPRISLHVRDLSIVASKTNTTLVNTFSMDLPSGSVMAVMGGSGSGKTTLLNVLASKISGGLTHNGSIRYVLEDTGSEPNETEPKRAHLDGQDHPIQKHVIMAYLPQQDVLSPRLTCRETLKFAADLKLNSSERTKKLMVEQLIEELGLKDCADTLVGDNSHRGLSGGEKRRLSIGTQMISNPSIMFLDEPTTGLDAYSAFLVIKTLKKLAKEDGRTFIMSIHQPRSDILFLLDQVCILSKGNVVYCDKMDNTIPYFESIGYHVPQLVNPADYFIDLSSVDSRSDKEEAATQSRLNSLIDHWHDYERTHLQLQAESYISNATEIQIQNMTTRLPFWKQVTVLTRRNFKLNFSDYVTLISTFAEPLIIGTVCGWIYYKPDKSSIGGLRTTTACLYASTILQCYLYLLFDTYRLCEQDIALYDRERAEGSVTPLAFIVARKISLFLSDDFAMTMIFVSITYFMFGLEADARKFFYQFAVVFLCQLSCSGLSMLSVAVSRDFSKASLVGNMTFTVLSMGCGFFVNAKVMPVYVRWIKYIAFTWYSFGTLMSSTFTNSYCTTDNLDECLGNQILEVYGFPRNWITVPAVVLLCWSVGYFVVGAIILYLHKIDITLQNEVKSKQKKIKKKSPTGMKPEIQLLDDVYHQKDLEAEKGKNIHITIKLEDIDLRVIFSAPFSNWKEGNFHHETKEILQSVNAIFKPGMINAIMGPSGSGKSSLLNLISGRLKSSVFAKFDTSGSIMFNDIQVSELMFKNVCSYVSQDDDHLLAALTVKETLKYAAALRLH--HLTEAERMERTDNLIRSLGLKHCENNIIGNEFVKGISGGEKRRVTMGVQLLNDPPILLLDEPTSGLDSFTSATILEILEKLCREQGKTIIITIHQPRSELFKRFGNVLLLAKSGRTAFNGSPDEMIAYFTELGYNCPSFTNVADFFLDLISVNTQNEQNEISSRARVEKILSAWKANMDNESLSPTP------------------ISEKQQYSQESFFTEYSEFVR---------------------------------------------------------------------------------KPANLVLAYIVNVKRQFTTTRRSFDSLMARIAQIPGLGVIFALFFAPVKHNYTS---ISNRLGLAQESTALYFVGMLGNLACYPTERDYFYEEYNDNVYGIAPFFLAYMTLELPLSALASVLYAVFTVLACGLPRTAGNFFATVYCSFIVTCCGEALGIMTNTFFERPGFVVNCISIILSIGTQMSGLMSLGMSR------VLKGFNYLNPVGYTSMIIINFAFPGN-LKLTCEDGGKNSDGTCEFANGHDVLVSYGLVRNT--QKYLGIIVCVAIIYRLIAFFILKAKLEWIKW----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :. . .::*.:*.*:::*:: :: * : :: * :** * : : : :: : * :*.*:::*: :. :*: :* ::::****:*** . : * : .: :: :* * : ::. :. : :: * : * : : ** . .: :: . : * : . . : * : * : * : . . : . . .. : : : . :. ", "identical_positions": 33, "similar_positions": 91, "identity": "2.31%" }, { "cls_id": "homologset.agr.SGD:S000005436", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6QI44-1", "uniprot_id": "NAA25_RAT", "id": "Q6QI44-1", "name": "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "aln": "-MATRGHVQDPNDRRLRPIYDYLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAA-----LEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIV-----PKNPYYFWSVMSLIMQSISARDENLS--KTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILERLG-KYQEALDVIRGKLGEKLTSEIQSRENKCMAMYKKLSKWP-ECNALSRRLLLKNSDDWQFYLTYFDSVFRLIEEAWTPPAEGEHSLEGEVHCSAEDAVKFIEDRITEASQSSRHVRGPHLAKLELIRRLRSQGCNDEFRLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPAAQCTQFINQLLGVVPLSTPTEDKLALPADIRGLQQHLCVVQLTRLLGLYHSMDKNQKLDVVRELMLRYQHG-LEFGRSCLKTELQFSDYYCLLAVHVLIDIWREAGEETAVWQALTLLEEGLTHSPSNAQFKLLLVRIYCVLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAASLGQYAAA---SQSCNFALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTSLAESIKSMNLRPEEDDVPWEDLRDNRDLDVFFSWDPKDRNVSEEHKKLSLEEETMWLRIRSLTLRLISALPSLTHPVEPRNSEKTSENGVSSRVDVLRLLLQQLEVAVETGKRFIEKEIQYPFLG-PVPTRMGRFFSSGCCQCQVHSFHLVSDVYELDTSGLEGTVDIQERIENSLASLLELLKGVFSTCKGDLLEVKDGNVKTQPAVLENLVFFVETISIVLWVSSYCESVLRPYKLNIQKKKKKKKETSIVMPPIFTSFQDYVTGLQTVISNAVDHIKGLEAHLIALKLEELTLEDTSISPVN--LSNCHVLSVRRRDPGSYWKLGAVEPMCADVCPSVQI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BWZ3-1", "uniprot_id": "NAA25_MOUSE", "id": "Q8BWZ3-1", "name": "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "aln": "-MATRGHVQDPNDRRLRPIYDYLDNGNNKMAIQQADKLLKKHKDLHCAKVLKAIGLQRTGKQEEAFTLAQEVAA-----LEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIV-----PKNPYYFWSVMSLIMQSISARDENLS--KTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILERLG-KYQEALDVIRGKLGEKLTSEIQSRENKCMAMYKKLSKWP-ECNALSRRLLLKNSDDWQFYLTYFDSVFRLIEEAWTPPAEGEHSLEGEVHCSAEDAVKFIEDRITEASQSSRHVRGPHLAKLELIRRLRSQGCNDEYKLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPAAQCTQFINQLLGVVPLSTPTEDKLALPADIRGLQQHLCVVQLTRLLGLYHSMDKSQKLDVVKELMLRYQHG-LEFGRSCLKTELQFSDYYCLLAVHVLIDVWREAGEETAVWQALTLLEEGLTHSPSNAQFKLLLVRIYCVLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAASLGQYAAA---SQSCNFALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISISLAESIKSMNLRPEEDDVPWEDLRDNRDLDVFFSWDPKDRNVSEEHKKLSLEEETMWLRIRSLTLRLISGLPSLTHPVEPKNSEKMSENGVSSRIDILRLLLQQLEVAVETGKRFIEKEIQYPFLG-PVPTRMGRFFSSGCCQCQVQSFHLVSDMYELDTSGLEGTVDIQERIENSLASLLELLKGVFSTCKGDLLEVTDGNVKTQPAVLENLVFFVETISVILWVSSYCESVLRPYKLNIQKKKKKKKETSIIMPPIFTSFQDYVTGLQTVISNAVDHIKGLEAHLIALRLEELTLEETSISTEERKFSKTVQGKVQSSYLHSLLETGELLRKRLETTKKLKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14CX7-1", "uniprot_id": "NAA25_HUMAN", "id": "Q14CX7-1", "name": "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "aln": "-MATRGHVQDPNDRRLRPIYDYLDNGNNKMAIQQADKLLKKHKDLHCAKVLKAIGLQRTGKQEEAFTLAQEVAA-----LEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIV-----PKNPYYFWSVMSLIMQSISAQDENLS--KTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILERLG-KYQEALDVIRGKLGEKLTSEIQSRENKCMAMYKKLSRWP-ECNALSRRLLLKNSDDWQFYLTYFDSVFRLIEEAWSPPAEGEHSLEGEVHYSAEKAVKFIEDRITEESKSSRHLRGPHLAKLELIRRLRSQGCNDEYKLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPATQCTKFINQLLGVVPLSTPTEDKLALPADIRALQQHLCVVQLTRLLGLYHTMDKNQKLSVVRELMLRYQHG-LEFGKTCLKTELQFSDYYCLLAVHALIDVWRETGDETTVWQALTLLEEGLTHSPSNAQFKLLLVRIYCMLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAESLGQYAAA---SQSCNFALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTSLAESIKSMNLRPEEDDIPWEDLRDNRDLNVFFSWDPKDRDVSEEHKKLSLEEETLWLRIRSLTLRLISGLPSLNHPVEPKNSEKTAENGVSSRIDILRLLLQQLEATLETGKRFIEKDIQYPFLG-PVPTRMGGFFNSGCSQCQISSFYLVNDIYELDTSGLEDTMEIQERIENSFKSLLDQLKDVFSKCKGDLLEVKDGNLKTHPTLLENLVFFVETISVILWVSSYCESVLRPYKLNLQKKKKKKKETSIIMPPVFTSFQDYVTGLQTLISNVVDHIKGLETHLIALKLEELILEDTSLSPEERKFSKTVQGKVQSSYLHSLLEMGELLKKRLETTKKLKI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDQ7-1", "uniprot_id": "NAA25_DROME", "id": "Q9VDQ7-1", "name": "Phagocyte signaling-impaired protein", "aln": "MAQQQGMDSALFERRLRPVYDNLEVGNNRKALQESEKLLRKHPNLLCARALKGLSLLRLGRYDESHGCLQTVAE-----EKPTDDSTLQVLSFCYREMEQLDKIVELYQHAVKQNPGNEELLAHLFISHVRVEDYKAQQAVALQLYKAQ-----PKNAYYFWSVISVVFQGIRGPESALPEKRKIYLGLAQRMVDKHIKEGKMETEQEAFLYLHILKLQN-KYQEAWEFLTGELCAKLYPGAP--VSMKFELLKELGNWR-ELNELLQQLLDADRDRWDFYKEYIQSSFELLKLTPQGVENGDK-------DSLARCQEFLQRIID---SSERKKRGPYLARLELHQRMRAEQLPAEKLIGDFDEMVIEYFRLFGDKSCCTHDIALFLPSISMNQRQALASKLLLESGVTS-----TSLPKNKEQLQKHLCALQISRMCGSHMDLPADHLLAFYTALKLHYEHGRTTFGKKLLATEMGPSDAYALLAANVMYDLSRRENKSDHLFEALCLLQYVLRNSTSNFHVKLLSLKIYHLFGCQVGAQEMYEYLDIKQIQLDSMGYVHCQLLALGGRFSGN---RNVYDATLKFFTNSYKERLEYIALTYRFCTFSKMEEFMNFKERLTNSLQYVACSVEAQICDLVSCYGNITQNLSAYVAMSIEPAEDRIAWHELSDNRDLGAIIRWDPLHEVDAAEERRESFDQEVEVLQVRSLMLRLFASFIDLYHGAGLKDSPAGAETAT------LELLRESWTGLFQRLRVMNYKPLAQKFLVNLLPTRLHLLLDMPYERFFDDLAQLVLDLQSGSAKLAEQCKRVGDNVIATMELCVQTINESNESNGIDGLWKRRGQQQKVAASLEMLSLYAFLLSVLNDKLQVSSKTKTKKKP---VENKVDGPQPISEKERSQMLQELMRQLKHKFEACDTAIRSWKAPVLPRDLSSFMSDMSLKPEVEATLIGDVSATFKDSHELMVTELRNLLKDKIRMVAK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12387-1", "uniprot_id": "NAA25_YEAST", "id": "Q12387-1", "name": "N-terminal acetyltransferase B complex subunit MDM20", "aln": "----------MSDKIQEEILGLVSRSNFKQCYAKLGQLQKQFPNALYFKILETYVKFKQSPGKFDYNKLLEEPYGLKGTTITGDTRSLEFLHNFFVELGKYDEALHVYERGNFKFP-SYELSYHWFMKALEDSNYNQMSKASLQLAKYSDSGNLPKRAYYFWNAISILAVSR-FQENTLSDPKKILLSRLARQSLLDLKP--FQNVQEIIVYCLVLDELFPQSREISEEIVAITFANFDTSVNLYLKNFILKHTKLLNSPQKLFEVCSKLIEKGLDDYELITNLIDAAYKLSKSKDE-----------------------VKQWIDENLGDSRNTR---LARLKLDIMYTDSVS---------ESSLSYYLSKYHNKPCCSIDLNHYSGHINIDMLKSIMSKYD----------------PEDKDLIHHCNILELG--------LIGSDSINNYNKFKGTLEKK----------SVTDYSSCSTFLLEIVKDKCKKTNPELKDVLLCITILENYQAKDPHNFDTMCWLIVLYMYLGLVPDAYFHFINLKIKNVQTDSLDYMIFSRFSTLFPNKQSDFYSKTFHEHNNLYDTSLANLPRYIQVAFERNSYSKILGMLEMRDKLMKSYTRWTKTLENLQFSRLCNDKRGHLLQKLHEDWRSLEMTQSVSFSDNRDFSILDENFAQFLNRGKILEYAN----------LNEESIFLTLIRELIIEALPNGEKTEQIS------------------------------------ALLKKLPSINLEELLNNNLTEVESASFLIFFEIYE------NNGKNLHDLISRLMKVPINAKQN----------WMVSHTYLTKMATLKTLDSLKRIK--------------------------------------DKEIQKLIKNSLKELRSCCDDVFKGYSKALVQAYEELKKDECGNLLKELDVKAENVKNIKNSLLGIQKSVRNL-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . : . :. .* : . : :* ::. : : *: : . . . . . * :*: * : *: : : .:*: . : * . * * *: . :*: . ..: * * **..****..:*:: . :. *. :.: * * :* :: * :* :*. : :* : : . :: . . : .:* . : : :*: . * ::: ::: :.* : :: * ..*: * **:*:* . :. : *: : :*.** *: : : : .: : . * :* ::: : .. : : :: : *. :* . . : . : .: :*: :.. * . : :* :* . : *. *::* *::.*: : . .:: .. : .** ::. ::.*: :: ::::* :* * . : . : :.: : * *. : . *. .*: * *: : : . :* . .: ::. . :. :: . : : : : : :: : . : *: * :*. : : : : : ..: : : . ..: . : ", "identical_positions": 75, "similar_positions": 236, "identity": "7.56%" }, { "cls_id": "homologset.agr.SGD:S000005437", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DCA5-1", "uniprot_id": "BRX1_MOUSE", "id": "Q9DCA5-1", "name": "Ribosome biogenesis protein BRX1 homolog", "aln": "MAATKRKRRGGLEVQAKKPKRSSKDAGQPAKQADVAKEAEEENRDRIPGPVCKGKWKNKERILIFSSRGINFRTRHLMQDLRMLMPHSKADTKMDRKDKLFVINEVCEMKNCNKCIYFEAKKKQDLYMWLSNSP--HGPSAKFLVQNIHTLAELKMTGNCLKGSRPLLSFDPAFDDLPHYALLKEFLIQIFSTPRYHPKSQPFVDHVFTFTILDNRIWFRNFQIIE------------EDAALVEIGPRFVLNLIKIFQGSFGGPTLYENPHYQSPNMHRRVIRSITAAKYRERQQVKDVQKLRK-------KEPKTILPHDP---TADVFVIPAEEKPVEIQWVKPEPKVDLKARKRRIYKRHRKLQQKMSRGSAK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4QQT6-1", "uniprot_id": "BRX1_RAT", "id": "Q4QQT6-1", "name": "Ribosome biogenesis protein BRX1 homolog", "aln": "MAATKRKRRGDLEVQAKKPKKNRKDAGQPAKQADVAKEAEEE-KDRIPGPVCKGKWKNKERILIFSSRGINFRTRHLMQDLRMLMPHSKADTKMDRKDKLFVINEVCEMKNCNKCIYFEAKKKQDLYMWLSNSP--HGPSAKFLVQNIHTLAELKMTGNCLKGSRPLLSFDPAFDDLPHYALLKEFLIQIFSTPRYHPKSQPFVDHVFTFTILDNRIWFRNFQIIE------------EDAALVEIGPRFVLNLIKIFQGSFGGPTLYENPHYQSPNMHRRVVRSITAAKYREKQQVKDVQKSRK-------KEPKTILPHDP---TADVFVTPAEEKPIEVQWVKPEPKVDLKARKRRIYKRHRKLQQKMSRGGAK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TDN6-1", "uniprot_id": "BRX1_HUMAN", "id": "Q8TDN6-1", "name": "Ribosome biogenesis protein BRX1 homolog", "aln": "MAATKRKRRGGFAVQAKKPKRNEIDAEPPAKRHATAEEVEEEERDRIPGPVCKGKWKNKERILIFSSRGINFRTRHLMQDLRMLMPHSKADTKMDRKDKLFVINEVCEMKNCNKCIYFEAKKKQDLYMWLSNSP--HGPSAKFLVQNIHTLAELKMTGNCLKGSRPLLSFDPAFDELPHYALLKELLIQIFSTPRYHPKSQPFVDHVFTFTILDNRIWFRNFQIIE------------EDAALVEIGPRFVLNLIKIFQGSFGGPTLYENPHYQSPNMHRRVIRSITAAKYREKQQVKDVQKLRK-------KEPKTLLPHDP---TADVFVTPAEEKPIEIQWVKPEPKVDLKARKKRIYKRQRKMKQRMDSGKTK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZE6-1", "uniprot_id": "BRX1_DROME", "id": "Q9VZE6-1", "name": "Ribosome biogenesis protein BRX1 homolog", "aln": "MGRKFQNKKKKAAPQLEIVPLDENPPLPPQRSSD----------DVVPKKARKEKWVNKQRVLVFSARGISHRDRHLMKDIKTLMPHHRPESKMERSKTLSVVNEMCEMKHCNKAMLFEGRRKRDLYMWISNTSGSTGPSAKFLIENIHTMAELKMTGNCLRGSRPLLSFDSKFDELPHLKLLKELFVQTYSVPNHHPKSQPFVDHVFTFTYLDKRIWFRNFQILS------------EDGGLSEVGPRYVMNPVKIFDGSFTGKTIWENPDYVSPSKQRQVLKKAAKDKYVNRVEQKVKHEATRPIRAYDGMDNDELFEDDDPVETAKILAAIAKKKKEEAAKQTPKSALTKKIKEKQLQAVKDVIERKKARTIKRVKKV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08235-1", "uniprot_id": "BRX1_YEAST", "id": "Q08235-1", "name": "Ribosome biogenesis protein BRX1", "aln": "MSSIYKALAG-----------KSKDNKSEKKQGN------------------VKQFMNKQRTLLISSRGVNYRHRHLIQDLSGLLPHSRKEPKLDTKKDLQQLNEIAELYNCNNVLFFEARKHQDLYLWLSKPP--NGPTIKFYIQNLHTMDELNFTGNCLKGSRPVLSFDQRFESSPHYQLIKELLVHNFGVPPNARKSKPFIDHVMSFSIVDDKIWVRTYEISHSTKNKEEYEDGEEDISLVEIGPRFVMTVILILEGSFGGPKIYENKQYVSPNVVRAQIKQQAAEEAKSRAEAAVERKIKR---------RENVLAADP-------------------------------LSNDALFK-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : . : :: **:* *::*:**:..* ***::*: *:** : :.*:: .. * :**:.*: :**: : **.::::***:*:*:.. **: ** ::*:**: **::*****:****:**** *:. ** *:**:::: :..* **:**:***::*: :*.:**.*.::* ** .* *:***:*:. : *::*** * .::** .* **. * ::. : : .: : :: : . :: * : : ", "identical_positions": 92, "similar_positions": 101, "identity": "24.15%" }, { "cls_id": "homologset.agr.SGD:S000005438", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BKH7-1", "uniprot_id": "SIN1_MOUSE", "id": "Q8BKH7-1", "name": "Target of rapamycin complex 2 subunit MAPKAP1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKTHPPSVPGDSGSEVQG-------------------------------------SSGETQGYIYAQSVDITSS------WDFGIRR-RSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQ--------------------------------------------------------------ELKS-----LFEKKSLKE--------------------------------------------------KPPSS-------GKQSILSVRLEQC-------------------------------PLQLNNPFN--------------EYSKFDGKGHVGTTATKKIDVYLPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDN---------VSAYCLHIAEDDGEVDTD-FPPLDSNEPIHKFGFSTLALVEKYSSP-------GLTSKE---SLFVRINAAHGFSLIQVDNTKVTMKEILLKAVKRRKGSQKISGPQYRLEKQSEPNIAVDLESTLES--QNAWEFCLVRE---NSSRADG--------------VFEEDSQIDIATVQDMLSSHHYKSFKVSMIH------------------------------------------------RLRFTTDVQLGISGDKVEIDPVTNQKASTK-------------FWIKQKPISIDCDLLCACDLAEEKSPSHAV----FKLTYLSS--HDYKHLYFESDAAT----------------------------VSEIVLKVNYILESRASTARADYLAQKQRKLNRRTSFSFQKEKKSGQQ--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYF1-1", "uniprot_id": "SIN1_RAT", "id": "Q6AYF1-1", "name": "Target of rapamycin complex 2 subunit MAPKAP1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKTHPPSVPGDSGSEVQG-------------------------------------SSGETQGYIYAQSVDITSS------WDFGIRR-RSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQ--------------------------------------------------------------ELKS-----LFEKKSLKE--------------------------------------------------KPPSS-------GKQSILSVRLEQC-------------------------------PLQLNNPFN--------------EYSKFDGKGHVGTTATKKIDVYLPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDN---------VSAYCLHIAEDDGEVDTD-FPPLDSNEPIHKFGFSTLALVEKYSSP-------GLTSKE---SLFVRINAAHGFSLIQVDNTKVTMKEILLKALKRRKGSQKISGPQYRLEKQSEPNIGVDLESTLES--QNAWEFCLVRE---NSSRADG--------------VFEEDSQIDIATVQDMLSSHHYKSFKVSMIH------------------------------------------------RLRFTTDVQLGISGDKVEIDPVTNQKASTK-------------FWIKQKPISIDCDLLCACDLAEEKSPSHAV----FKLTYLSS--HDYKHLYFESDAAT----------------------------VSEIVLKVNYILESRASTARADYFAQKQRKLNRRTSFSFQKEKKSGQQ--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BPZ7-1", "uniprot_id": "SIN1_HUMAN", "id": "Q9BPZ7-1", "name": "Target of rapamycin complex 2 subunit MAPKAP1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQG-------------------------------------SNGETQGYVYAQSVDITSS------WDFGIRR-RSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQ--------------------------------------------------------------ELKS-----LFEKKSLKE--------------------------------------------------KPPIS-------GKQSILSVRLEQC-------------------------------PLQLNNPFN--------------EYSKFDGKGHVGTTATKKIDVYLPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDN---------VSAYCLHIAEDDGEVDTD-FPPLDSNEPIHKFGFSTLALVEKYSSP-------GLTSKE---SLFVRINAAHGFSLIQVDNTKVTMKEILLKAVKRRKGSQKVSGPQYRLEKQSEPNVAVDLDSTLES--QSAWEFCLVRE---NSSRADG--------------VFEEDSQIDIATVQDMLSSHHYKSFKVSMIH------------------------------------------------RLRFTTDVQLGISGDKVEIDPVTNQKASTK-------------FWIKQKPISIDSDLLCACDLAEEKSPSHAI----FKLTYLSN--HDYKHLYFESDAAT----------------------------VNEIVLKVNYILESRASTARADYFAQKQRKLNRRTSFSFQKEKKSGQQ--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V719-1", "uniprot_id": "SIN1_DROME", "id": "Q9V719-1", "name": "Stress-activated map kinase-interacting protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATYSNQHWLLSHIRNSFISTDDTGMCETVMLSDDMPKHYLRKFGNSGAGGDHYHWRRAHKTPPTGGGTTPERNTRHPDAPLQEVDFICYPGLDLSDDEEDMSTHSFDIQMY------PEVGAHRFRSNTAQKLEKLDIAKRRAARIKSVNYQEEVQPPESD--------------------------------------------------------------DFFKRKELPLSKAERVKN--------------------------------------------------EPKANDDDLSDEGVQSQLTEQLAKS-------------------------------PKQAQNRFI--------------EFARFDGTSQVG-MQTKRINVFLNMLPEPDRNYPLKICVVATAKIQEVIGFVCYRTSLQYPDVPLKS----------LQHYALYMTEDN-DDMED-FPPLDNREPCSKFGFSQLTLAERRPLA-------PVTRVDYHSQLGSKSMTSVEDKTALSDAAVKALQNISLNGGTSDPGGGGGGGDSPHDNVKEYEKRLLNHNDMLEAPMHRTFRLNIIDKRFFKSDVTLG--------------ISGERIEIDQCKNAKFWPQKKPVSTPIDFVA------------------------------------------------HCEILERRHLKALLRIWLKSNSSSPSFSTG-------------CTSAPINASVTTLNAGSGSGGIAHSPSSPG----HSSGLFSSSNIRFKHYDFDTDTHT----------------------------AEQIHNKLNCILEMRSSDLRREFLLQRDRKQEKRQLKL------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08236-1", "uniprot_id": "AVO1_YEAST", "id": "Q08236-1", "name": "Target of rapamycin complex 2 subunit AVO1", "aln": "MDTVTVLNELRAQFLRVCPEKDQMKRIIKPYIPVDEFNTEQCLDSSIRELYMNSDGVSLLPELESPPVSKDFMENYASLGKMRIMRENEGQKGKANQNLIGAEKTERDEEETRNLQDKSAKNTLIVEENGTLRYNPLNSSASNSLLNDDDHTSGKHHKTSSKEDSYLNSSMEMQKKSSKRSSLPFVRIFKSRRDHSNTSGNKNVMNTTNTRAKSSTLHPPGARHNKKGSKFDMNFDFDENLEEEDDDDDDDEEGDDIHSQFFQLDDDFDAKGSGASPAHKGINGMSNNKNNTYTNNRNSISILDDRESSNGNIGSASRLKSHFPTSQKGKIFLTDNKNDGQKSDSLNANKG-IHGDGSSASGNGSVSRDGLTETESNNISDMESYINEKDLDDLNFDTVTSNINKTVSDLGGHESTNDGTAVMNRDSKDSRSNSNEFNAQNRDRITPGSSYGKSLLGSEYSEERYSNNDSSTMESGEMSLDSDMQTNTIPSHSIPMSMQKYGIYHGDDDSTLNNVFDKAVLTMNSSRHPKERRDTVISGKEPTSLTSSNRKFSVSSNLTSTRSPLLRGHGRTSSTASSEHMKAPKVSDSVLHRARKSTLTLKQDHSQPSVPSSVHKSSKEGNILIEKTTDYLVSKPKASQLSNMFNKKKKRTNTNSVDVLEYFSFVCGDKVPNYESMGLEIYIQASKKYKRNS-FTTKVRKSSTIFEVIGFALFLYSTEKKPDNFEEDGLTVEDISNPNNFSLKIVDEDGEPFEDNFGKLDRKSTIQSISDSEVVLCKVDDAEKSQNEIETPLPFETGGGLMDASTLDANSSHDTTDGTINQLSFYKPIIGNEDDIDKTNGSKIIDVTVYLYPNVNPKFNYTTISVLVTSHINDILVKYCKMKNMDPNEYALKVLGKNYILDLNDTVLRLDGINKVELISKKDARELHLEKMKPDLKKPVLPTIQSNDLTPLTLEPLNSYLKADAGGAVAAIPENTKVTSKAKKISTKYKLGLAKQHSSSSVASGSVSTAGGLANGNGFFKNKNSSKSSLHGTLQFHNINRSQSTMEHTPDTPNGVGDNFQDLFTGAYHKYKVWRRQQMSFINKHERTLAIDGDYIYIVPPEGRIHWHDNVKTKSLHISQVVLVKKSKRVPEHFKIFVRREGQDDIKRYYFEAVSGQECTEIVTRLQNLLSAYRMNHK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: : : :..: * .. : . .*.. . . : : ..* :.* :. .: : ::: : . . : ::. .: :. . : . . *: :. . :* *: : :. . * .* * *: * .:* : ::::: . .* :. . :: : ::**: : : : ::. . :.* :.::: : * * ** ... .:. * :.* : : * . * : :. . . .. : . : : : :: : .. . : .:* . .: ..:. . :. : .: :* . :. :: :: . ::*. . ::. :* : : .. ::. :: : * :.: *: : ", "identical_positions": 32, "similar_positions": 169, "identity": "2.72%" }, { "cls_id": "homologset.agr.SGD:S000005440", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PAQ4-1", "uniprot_id": "REXO4_MOUSE", "id": "Q6PAQ4-1", "name": "RNA exonuclease 4", "aln": "MCACAVAGVAVSSLVVPTAESGEMKTKATAPVPQPGPIRKLARKKAKKK--FRKSKALAGSGVPGSHPAAVAGRPPKAPENFSQNWKALQE-LLKQKSQAAEKPL-VSQMDDKMHPQIIQQNRKKASDKSKGDKQRTEKAK-STRGSVTSAP-TDRKILVPPTDTSGTEQ-KKGAKKRTYSDISSHQGALKP-KWKATEAAVILNQPTPTEEDIWFDDVDPDDIEDAIGPEAAMLVRKRLGQKKR--TISLEKEQAFGGLTKALALDCEMVGVGPKGEESIAARVSIVNQYGKCVYDKYVKPTEPVTDYRTAVSGIRPENLKQGEEFEVVKKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDTQKFKPFRSRVK-SGRPSLKRLSEKILGIRVQQAEHCSIQDAQAAMRLYVMVKREWESSTANRRAPAATPQHRIKNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7ESM1-1", "uniprot_id": "F7ESM1_RAT", "id": "F7ESM1-1", "name": "RNA exonuclease 4", "aln": "-YASAVT--RVSSLLARAAESEKMKTKATAPVPQPGPIRKLVRKKAKKK--FKKSKALGGSGTPGSRPATVASRPPKAPENFSQNWKALQE-LLKRKSEAPEKPR-ISQLDDKIHHQIIQKNRKKTSDKSKGDK-RTEDDK-PTRDSVTSAPKKVRKTPVPPTNASGTEQ-KKGAEKRTRSDLSSHQGDIKH-KGKAKEAAVILSQPTPTEEDIWFDDVDPDDIEAAVGPEAAMLVRKRLGQRTS--TISLVKEQAFGGLTKALALDCEMVGVGPKGEESIAARVSIVNQYGKCVYDKYVKPTEPVTDYRTAVSGIRPENLKQGEEFEVVKKEVAAMLKGRILVGHALRNDLKVLFLEHPKKKIRDTQKFKPFRSLVK-SARPSLKQLSEKILGLRVQQAEHCSVQDAQAAMRLYIMVKRKWESIAADRRAPAATPHHCNEYA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9GZR2-1", "uniprot_id": "REXO4_HUMAN", "id": "Q9GZR2-1", "name": "RNA exonuclease 4", "aln": "---------------MGKAKVPASKRAPSSPVAKPGPVKTLTRKKNKKKKRFWKSKAREVSKKPASGPGAVV-RPPKAPEDFSQNWKALQEWLLKQKSQAPEKPLVISQMGSKKKPKIIQQNKKETSPQVKGEEMPAGKDQEASRGSVPSGSKMDRRAPVPRTKASGTEHNKKGTKERTNGDIVPERGDIEHKKRKAKEAAPAP----PTEEDIWFDDVDPADIEAAIGPEAAKIARKQLGQSEGSVSLSLVKEQAFGGLTRALALDCEMVGVGPKGEESMAARVSIVNQYGKCVYDKYVKPTEPVTDYRTAVSGIRPENLKQGEELEVVQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDTQKYKPFKSQVK-SGRPSLRLLSEKILGLQVQQAEHCSIQDAQAAMRLYVMVKKEWESMARDRRPLLTAPDHCSDDA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VUC3-1", "uniprot_id": "Q9VUC3_DROME", "id": "Q9VUC3-1", "name": "RNA exonuclease 4", "aln": "-------------------------------------------------------------------------------------------------------------MSATPRQKQFDMNRSRANNLDSSRSGSANNKNTTDSTKNVVSPQHNQRKLQASMERLQVQQVNTSRRAAGSNWMAAAGG--------------------GAAAAAGSENQDAKATESAPLSKSARMRMKKKAHRNR-----------------ILAMDCEMVGVGHNTRDDMLARVSIVNRMGHVLLDKYVKPRKEVTDYRTSVSGIRPQDIANGEDFAAVQNEVMKLIHGRILVGHGLRNDLAVLGIRHPFHDIRDTSHYKPLCKLISNTHTPSLKRLTKAVLGQEIQTGEHNSVEDARAAMGIYNRVAVDWEKYLEKKRHQQQHY-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08237-1", "uniprot_id": "REXO4_YEAST", "id": "Q08237-1", "name": "RNA exonuclease 4", "aln": "-------------------------------------------------------------------------------------------------------------MALSSNWQALLASESNPTSNGKNKQSNRKIRNVKKVSKTVNVSSTTQYAPRKRKNGSKIMDMVYNMNKEISKHEK------------------------DKLEGKVFEFNPNKANTSTTIKEPVKVGISEDTRINS---------NKSKEIGKYIAMDCEFVGVGPEGKESALARISIVNYFGHVVLDEFVKPREKVVEWRTWVSGIKPEHMKNAITFKEAQKKTADILEGRILVGHALKHDLEALMLSHPKSLLRDTSRHLPFRKLYAKGKTPSLKKLTREVLKISIQEGEHSSVEDARATMLLYKKEKTEFEKIHRNTFN------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : : ...... .. . : . . : . . . . : : :.. : .. : :*:***:**** : .:. **:**** *: : *::*** : *.::** ****:*:.: :. : .:::. ::.*******.*::** .* : ** :***.:. *: . ***: *:. :* :* .** *::**:*:* :* .:*. . ", "identical_positions": 59, "similar_positions": 88, "identity": "13.32%" }, { "cls_id": "homologset.agr.SGD:S000005441", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q04690-1", "uniprot_id": "NF1_MOUSE", "id": "Q04690-1", "name": "Neurofibromin", "aln": "-------------------------------------------MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLIN----ISKYKFSLVISGLTTILKNVNNMRIFG--------------------------------------EAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHFLH-------------------TCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVD--------------VHDIELLQYINVDCAKLKRLLKETA-FKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQTDMAECAEKLFDLVDGFAESTKR-KAAVWPLQIILLILCPEIIQDISKDVVDESNINKK----------------------LFLDSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWED-NSVIFLLVQSMVVDLKNLLFNPSKPFSRGS---QPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPS-----------------------------TFHYVLVNSLH-----------------RIITNSALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTS-LKFKEKPTDLETRSYKCLLLSMVKLIHADPKLLLCNPRKQGPETQSSTAELITGLVQLVPQSHMPEVAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKK---LTSHQMLSSTEILKWLREILICRN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KFLLKNKQADRSSCHSLYLYGVGCEMSATGNTTQMSVDHDEFLRACTPGASLRKGRGNSSMDSTAGCSG-------------------TPPICRQAQTKLEVALYMFLWNPDTEAVLVAMSCFRHLCEEADIRCGVDEVSVHNFLPNYNTFMEFASVSNMMSTG------------------------------------RAALQKRVMALLRRIEHPTAGNIEAWEDTHAKWEQATKLILNYPKAKMEDGQAAES--------LHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINMTGFLCALG--------GVCLQQRSSS-----GLATYSPPMGAVSERKGSMISVMSSEGNIDS--------------------------------------PVSRFMDRLLSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQG--QVLLSDSNTQFVEQTIAIMKNLLDNHTE--------GSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVEVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAAD---DDIKCLT------RDLDQASMEAVVSLLAGLPLQ--------PEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTG------GRKRGMSRRLASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRVIITSSDWQHVSFEVDPTRLEPSESLEENQRNLLQMTEKFFHAIISSSSEFPSQLRSVCHCLYQATCHSLLNKATVKERKENKKSVVSQRFP---QNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKVLQSIAN-HVLFTKEEHMRPFNDFVKSNFDLARRFFLDIASDCPTSDAVNHSLSFISDGNVLALHRLLWNNQEKIG-------QYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVAD-------THWSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQINGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIYNCNS-WVREYTKYHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVFHNALKLAHKD----TKVSIKVGSTAVQVTSAERTKVLG------QSVFLNDIYYASEIEEICLVDEN----QFTLTIANQG---------TPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRP-KDVPGTLLNIALLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEPHLTLEFLEECISGFSKSSIELKHL--CLEYMTPWLSNLVRFCKHNDDAK-RQRVTAILDKLITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHLPYLFHVVTFLVATGPLSLRASTHGLLINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPKFYLLFGISKVKSAAVIAFRSSYRD---------RSFSPGSYERETFALTSLETVTEALLEIMEACMRDIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKA---------LESCLKGPDTYNSQVLIESTVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALLEQNLHTLDSLRIFNDK--SPEEVFMAIRNPLEWHCKQMDHFVGLNFN-SNFNFALVGHLLKGYRHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKSLLLTDISMENVPMDTYPIHHGDPSYRTLKETQPWSSPKGSEGYLAATYPAVGQTSPRARKSMSLDMGQPSQANTKKLL---GTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYEMETQRIPSSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILYEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEETSEESLLTPTSPYPPALQSQLSITANLNLSNSMTSLATSQHSP--------------------------------------------GLDKENVELSPTAGHCNSGRTRHGSASQVQKQRSAGSFKRNSIKKIV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P97526-1", "uniprot_id": "NF1_RAT", "id": "P97526-1", "name": "Neurofibromin", "aln": "-------------------------------------------MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLIN----ISKYKFSLVISGLTTILKNVNNMRIFG--------------------------------------EAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHFLH-------------------TCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVD--------------VHDIELLQYINVDCAKLKRLLKETA-FKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQTDMAECAGKLFDLVDGFAESTKR-KAAVWPLQIILLILCPEIIQDISRDVVDENNTNKK----------------------LFLDSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWED-NSVIFLLVQSMVVDLKNLLFNPSKPFSRGS---QPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPS-----------------------------TFHYVLVNSLH-----------------RIITNSAWDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPALRMAPSLTFKEKVTS-LKFKEKPTDLEARSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPEVAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKK---LTSHQMLSSTEILKWLREILICRN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KFLLKNKQADRSSCHSLYLYGVGCDLPASGNVTQMSVDHEESLRTCAPGASLRKGRGNSSMDSTAGCSG-------------------TPPICRQAQTKLEVALYMFLWSPDTEVVLVAMSCFRHLCEEADIRCGVDEVSVHNFLPNYNTFMEFASVSNMLSTG------------------------------------RAALQKRVMALLRRIEHPTAGNTEAWEDTHAKWEQATKLILNYPKAKMEDGQAAES--------LHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINMTGFLCALG--------GVCLQQRSSS-----GLATYSPPMGPVSERKGSMISVMSSEGNVDS--------------------------------------PVSRFMDRLLSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKSAISKFFDSQG--QVLLTDSNTQFVEQTIAIMKNLLDNHTE--------GSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVEVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAAD---DDVKCLT------RDLDQASMEAVVSLLAGLPLQ--------PEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTG------GRKRGMSRRLASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIIITSSDWQHVSFEVDPTRLEPSESLEENQRNLLQMTEKFFHAIISSSSEFPSQLRSVCHCLYQ---------------------VVSQRFP---QNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKVLQSIAN-HVLFTKEEHMRPFNDFVKSNFDLARRFFLDIASDCPTSDAVNHSLSFISDGNVLALHRLLWNNQEKIG-------QYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVAD-------THWSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQINGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIYNCNS-WVREYTKYHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVFHNALKLAHKD----TKVSIKVGSTAVQVTSAERTKVLG------QSVFLNDIYYASEIEEICLVDEN----QFTLTIANQG---------TPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRP-KDVPGTLLNIALLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEPHLTLEFLEECISGFSKSSIELKHL--CLEYMTPWLSNLVRFCKHNDDAK-RQRVTAILDKLITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPKFYLLFGISKVKSAAVIAFRSSYRD---------RSFSPGSYERETFALTSLETVTEALLEIMEACMRDIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKA---------LESCLKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALLEQNLHTLDSLRIFNDK--SPEEVFMAIRNPLEWHCKQMDHFVGLNFN-SNFNFALVGHLLKGYRHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKSLLLTDISMENVPMDTYPIHHGDPSSRTLKETQPWSSPRGSEGYLAATYPAVGQTSPRARKSMSLDMGQPSQANTKKLL---GTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYEMETQRISSSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILYEYLAEASVVFPKVFPLVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEETSEESLLTPTSPYPPALQSQLSITANLNLSNSMTSLATSQHSP--------------------------------------------GIDKENVELSPTTGHCNSGRTRHGSASQVQKQRSAGSFKRNSIKKIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21359-1", "uniprot_id": "NF1_HUMAN", "id": "P21359-1", "name": "Neurofibromin", "aln": "-------------------------------------------MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLIN----ISKYKFSLVISGLTTILKNVNNMRIFG--------------------------------------EAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHFLH-------------------TCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVD--------------VHDIELLQYINVDCAKLKRLLKETA-FKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQTDMAECAEKLFDLVDGFAESTKR-KAAVWPLQIILLILCPEIIQDISKDVVDENNMNKK----------------------LFLDSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWED-NSVIFLLVQSMVVDLKNLLFNPSKPFSRGS---QPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPS-----------------------------TFHYVLVNSLH-----------------RIITNSALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTS-LKFKEKPTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPEIAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKK---LTSHQMLSSTEILKWLREILICRN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KFLLKNKQADRSSCHFLLFYGVGCDIPSSGNTSQMSMDHEELLR--TPGASLRKGKGNSSMDSAAGCSG-------------------TPPICRQAQTKLEVALYMFLWNPDTEAVLVAMSCFRHLCEEADIRCGVDEVSVHNLLPNYNTFMEFASVSNMMSTG------------------------------------RAALQKRVMALLRRIEHPTAGNTEAWEDTHAKWEQATKLILNYPKAKMEDGQAAES--------LHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINMTGFLCALG--------GVCLQQRSNS-----GLATYSPPMGPVSERKGSMISVMSSEGNADT--------------------------------------PVSKFMDRLLSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQG--QVLLTDTNTQFVEQTIAIMKNLLDNHTE--------GSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVEVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAAD---DDVKCLT------RDLDQASMEAVVSLLAGLPLQ--------PEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDESAQTG------GRKRGMSRRLASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLEPSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFP---QNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIAN-HVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSFISDGNVLALHRLLWNNQEKIG-------QYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVAD-------THWSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQINGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIYNCNS-WVREYTKYHERLLTGLKGSKRLVFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVFHNALKLAHKD----TKVSIKVGSTAVQVTSAERTKVLG------QSVFLNDIYYASEIEEICLVDEN----QFTLTIANQG---------TPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRP-KDVPGTLLNIALLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEPHLTLEFLEECISGFSKSSIELKHL--CLEYMTPWLSNLVRFCKHNDDAK-RQRVTAILDKLITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPKFYLLFGISKVKSAAVIAFRSSYRD---------RSFSPGSYERETFALTSLETVTEALLEIMEACMRDIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKA---------LESCLKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALLEQNLHTLDSLRIFNDK--SPEEVFMAIRNPLEWHCKQMDHFVGLNFN-SNFNFALVGHLLKGYRHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKSLLLTDISMENVPMDTYPIHHGDPSYRTLKETQPWSSPKGSEGYLAATYPTVGQTSPRARKSMSLDMGQPSQANTKKLL---GTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYEMETQRISSSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILYEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEETSEESLLTPTSPYPPALQSQLSITANLNLSNSMTSLATSQHSP--------------------------------------------GIDKENVELSPTTGHCNSGRTRHGSASQVQKQRSAGSFKRNSIKKIV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PLQ0-1", "uniprot_id": "A0A8M9PLQ0_DANRE", "id": "A0A8M9PLQ0-1", "name": "Neurofibromin", "aln": "-------------------------------------------MAAHKPVEWVQAIINRFDEQLPIKTGQQSTHTKVSTEHNKECLIN----ISKYKFALVINGLTNILKNVNNMRIFG--------------------------------------EAAEKNLYFSQLIILDTLEKCLAGQPKDCLRLDEAMLVKQLLPEICHFLH-------------------SYREGQQHATQLRSSASAVLFSLSCNNFNAVFSRISTRLQELTVCTEDTVD--------------VHDIELIQYINVDCSKLKRLLQEAV-LKFKSLKKPAQLAVISSLEKAFWNWVEHYPDDFTMLYQRPQADMADCAERLFDLVDSFAESAKR-KAAVWPLQIILLILCPEITQSITKEVGGEEKANKK----------------------SFVDSLRKALGQHSGSKQLTESAAVACVKLCKACTYINWED-NSVIFLLVQSIVMDLKGLLFNPTKPFSRGTG-CQSADVDLMIDCFVSCYRINPRNNQHFKVCLASTSPP-----------------------------TFHFVLVNSLH-----------------KIITNSHLDWWPKIDAIYCYSGELRTMFADTLGRVIQSLSAHPPLRMTSSLTFKEKMTTSLKFKEKSTDLDSRS---LLLALVKLIHADPKLMLHNPGKPGQEIQNSTAEIIKGLVQLVPLTHSAELSQEAMEALLVLHQPETIELWNPDAPIETFWDISSQVLFLICKK---LIGHQMINSTEILKWLREILICRN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KFLLKNK-------------------------------------------------------ECATQGS-------------------LIPISRQAQTKLEVCLYTFLWSPDAEAVLVAMSCFRHLCEEADIRCSVDELPVHTVLPNYNTFIELASVSNMMATG------------------------------------RNTLQKRVMALLRRIKHPTAGNVEAWEDTYAKWEQATKQILNHPKNKVEDGQVVN-----------IRLVNYFIFFSIHGHLFSVRP----QEWINMTGFLCALG--------GVCLQQRSTP-----SLGTYSPPMGPLTERKGSMISMSSCEVNSET--------------------------------------SLNRFLERLLALMVCTHEKVGVQIRTNVKDLVGLELSPALYSMLFTKLRNSIGRFFDTQG--PVPITDANTLFVEQTIAIMKNLLDSHTE--------GSSEHLGQASIETMMLNLVRYVRILGNIVHAIQIKTKLCQLVEVMMERRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAAD---DDVKCLT------RDLDQASMEAVVSLLAGLPLQ--------PEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEEDGQQVA------GRKRGMSRRLASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGAAYLQKLLEPLLRGIITTPEWQQISFEVDPTRLEQAENLEENQKNLLQITDRFFLAIINSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFP---QNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIAN-HVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDSPPSDSVNHSLSFISDGNVLALHRLLWNNQERIG-------QYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVAD-------THWSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLNIFYQAGTSKNGNPVFYYIARRFKTGQINGDLLIYHVLLTLKPYYAKHYEIVVDLTHVGPSNRFKTDFLSKWFVVFPNFAYENVAAVYIYNCNT-WVREYTKYHERLLTGLKGSKKLVFIDSPARLAEHIEPEQQKLPAATLALEEDLKVFHNALKLAHRD----TKVSIKVGSTAVQVTSAERTRVLG------QPVFLNDIYYASEIEEICLVDEN----QFTLTIANQG---------TPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRP-KDVPGTLLNIALLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEPHLTLEFLEECISGFSKSSIELKHL--CLEYMTPWLRNLVRFCKHNDDAK-RQRVTAILDKLITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHLPYLFHVVTLLVATGPLSLRASTHGLVINIIHSLCTCSQLNFSEETKQVLRLSLTEFSLPKFYLLFGISKVKSAAVIAFRSSYRD---------RSFSPGSYERETFALSSLETVTEALLEIMEACMRDIPGCKWLDQWTELAQKFAFQYNPSLQPRALVVFGCISKRVTHGQLKQIIRILSKASPLLSIDRGLESCLKGPDNYNSQVLIEATVIALTKLQPLLDQDSPMHKALFWVAVAVLQLDEVNLYSAGTALLEQNLHTLDSLRVFNDK--SPEEVFMEIRKPLEWHCKQMDHFVGLNFA-SNFNFALVGHLLKGYRHPSSTTVARTVRILHTLLGLVGKHRSCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKSLLLSEVTMENFPMDTYTVYDTEPGCRLLRENQPWASPKVSERSLAPPYSTIGQTSLRPRKSMSVDMGQPSQANAKKLLGISGTRKSFDHLISESKAPKRPDMESGITTPPKMRRVSENDYEIETQRIANS----HLRKVSVSESNVLLDENVLTDPKIQTLLLTVLATLVKYTTDEFHQRILYEYLAEASVVFPKVFPVVHNLLDSKLSTVLSMCQDPNLLNPVHGIIQNVVYHEESPPQYQPSCLQSFGFNGLWRFAGPFSKQTQIPDYAELVVKFLDALIDTYLPGIEEEGGEESLRTPTSPYPPTVQSQLSITANLNLSNSMTSLATSQHSPEGPIVYRRSPTLSHPRTTEEVPPKTAACLPCSKSAVFPPHLVLPGIDKENVEISPTSSLSTSGRMRHGSASQVQKQRSAGSFKRPSIKKIV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBJ2-1", "uniprot_id": "Q9VBJ2_DROME", "id": "Q9VBJ2-1", "name": "", "aln": "--------------------------------------------MTQKPGEWASALLARFEDQLPNRIGAYGTQARMSQDQLVACLIH----ISRYRFSLVISGLTKMLQRVNEAALQNR-------------------------------------HEPERCYFESLVIILTTLERCLTNQTKDTARFEEAMNVKLLLREISQFVD-------------------VQSDSNPNAAQLKALASKVLFALSQNHFSAVFNRISARIQELTSCSEENPD--------------YNDIELIQHIDMDMIKLTKLLQETI-TKFRS-KRAPPLILLYSLEKAIWNWIEYHPQEFQDLQRGTNRDISTCWEPLMDFVEYFKTENKKSKTLVWPLQMLLLILNPSCLEAVVNELQQSEKEKEKDKEKVASKSAQSTSRDKDFSAKQFIESIKRGLGQHSPSKQVTESAAIACVKLCKASTYINNTDSNNVVFKLVQFFINDLKALLFNPAKPFSRGQG-YNFADIELMIDCWVSCFRINPHNIEALKVCLNLSSPQ-----------------------------AYHFVIVCSLLRLAHIYVDFRLQNKNPFRIVNQPRLSWWPQTDVVHYRSAELRALFTDTLNKATQGYIAHTPLRYITSLTLKSKDTQ----KGLTRAEEGPAHKMLLLLLVRLIHADPTLLLNTQGKVAHEVQSSTLELINGLVSLVHQTTMPDVAQEAMEALLALHAPEKIEVWNPEAPINTFWDVSSQVLFSISQK---LIQHQIANYTDVLKWLREILICRN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TFLQRHK-------------------------------------------------------DYAHVGS-------------------QIAICKQAHIKMEVVFFMYLWSVDLDAVLTSLSCFGLLCEEAEICCSSDELTVGFIMPNYHIYQELAQLSTSATDSRICFFDNTHGNVLS----------------------RLTLQKRIMTLLRKIEHCVHGVQPAWEETFRNWEVSSKVLQTYPKCKGEDG-QAEV--------FHRGMGKRRASHQSSEHDLEEQIN----EWANMTWFLLALG--------GVCLHKRSSSRQMLLQQSQNNASLGSLAQNSLYSSSTSSGHGSLHPSTVSLSTLP-------------------PAPPQDVSYCPVTQFVGQLLRLLVCSNEKIGLNIQKNVKELVGEEMSTQLYPILFDQVRAIVEKFFDQQGQVNVNVTDINTQFIEHTIYIMKSILDPKANKDPNNDQPSPSEHLGVTSIEGMMLGIVRYVRHLDMTVYAIRIKTKLCQLVEVMMKRRDDLAFRQEMKFRNKLVEYLTDWVMGTSHQIAPPSSADAAILTNTSLIFRDLDQACMEAVAALLRGLPLQ--------PEESDRGDLMDAKSALFLKYFTLFMNLLNDCIDSSEAEKEMNNTPLLPPRPRMAAGKLTALRNATILAMSNLLGANIDSGLMHSIDLGYNPDLQTRAAFMEVLTQILQQGTEFDTLAETVLADRFEQLVQLVTMISDKGELPIAMALANVVTTSQMDELARVLVTLFDAKHLLSPLLWNMFYREVEVSDCMQTLFRGNSLGSKIMAFCFKIYGASYLQMLLEPLIRPLLD--EEEETCFEVDPARLDPTEDIEQHRNNLIALTQKVFDAIINSSDRFPPQLRSMCHCLYQ---------------------VLSKRFPNLLQNNIGAVGTVIFLRFINPAIVSPQELGIVDKQVHSSAKRGLMLMSKILQNIAN-HVEFSKEQHMLCFNDFLRDHFEAGRRFFIQIASDCETVDQTSHSMSFISDANVLALHRLLWTHQEKIG-------DYLSSSRDHKAVGRRPFDKMATLLAYLGPPEHKPVDSHMMFSSYARWSSIDMSSTNFEEIMVKHQMHEKEEFKTLKSMNIFYQAGTSKSGYPVFYYIARRYKIGETNGDLLIYHVILTLKPFCHSPFEVVIDFTHTCSDNRFRTEFLQKWFYVLPTVAYENVHAVYIYNCNS-WVREYTKFHDRILAPLKGNRKLLFLESPNKLTDFIDAEQQKLPGATLSLDEDLKVFSNALKLSHKD----TKVAIKVGPTALQITSAEKTKVLA------HSVLLNDVYYASEIEEVCLVDDN----QFTLSITNES---------GQLSFIHNDCDNIVQAIIHIRNRWELSQPDSVTVHQKIRP-KDVPGTLLNMALLNLGSCDPNLRTAAYNLLCALTATFDLKIEGQLLETQGLCIPSNNTIFIKSVSEKLATNEPHLTLEFLEESIQGFQRSTIELKHL--CLEYMTPWLKNLVKFCKSNDDSK-KLKVSQILDKLINLTIDQKEMYPSVQAKIWGSIGQIPELIDMVLDNFLHKSITYGLGSPQVEIMADTAVALASANVQLVSKKVITRICRVMDKSCTNPTQYLEQHMMWDDIAILGRYLLMLSFNNCLDVATSVPYLFHTITFLVCSGSLSMRASTHGLVINIIHSLCTCTNPSFSEEAQRVLRLSLDEFSLPKFYLLFGISKVKSAAVTAFRSSCRHPTDKWLGNERVTQPLPADRERLSLPSLEVITDALLEIMEACMRDVPDCEWLNTWTSLARSFAFCYNPALQPRALIVYGCISKSVTDHEVKQLLRILVKA----------------LESFNDLILIEALVMCLTRIQPLLRPESPIHRALFWVAISVLQLDEITLYGAGLALLEQNLHTLKSQGCFDKKE-TIAEVMMKTREKLEWHFKQLDHAVGLSFR-SNFHFALVGHLIKGFRHPTPTTVSRTSRVLTMLLGIIAKPLHRDKFEVTPDSVAYLTALVAVSEEVRSRCHVKHALPRWPADLSSS--------VENGEASGGVQAIGLPLSRRQKS-------WDILDQSALQFAR----QHKVPTLQNARVLF---KTQRSFS--VPTTKDPNN---ATGIEE--RQERGS--------------------RSSVSNESNVLLDPEVLPDLSIQALVLTVLATLVKYSSDEGETRVLYQYLAEGSVVFPKVFPVIHSLLDQKINNILSVSHDQVVLNSVQNIIQNMLASED-PSQQQLHFLQSCGFGGLWRFAGPFTKYNMMGESSELFVNCLEAMVETCLP------GDESAPVPPSPRP------------YNLSSSLSSLTLGSPTDK-------------------------------------------AFSSESLDFYDNCPGSVSSLRRASHSKSRAKHRINDSPSH-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P19158-1", "uniprot_id": "IRA2_YEAST", "id": "P19158-1", "name": "Inhibitory regulator protein IRA2", "aln": "MSQPTKNKKKEHGTDSKSSRMTRTLVNHILFERILPILPVESNLSTYSEVEEYSSFISCRSVLINVTVSRDANAMVEGTLELIESLLQGHEIISDKGSSDVIESILIILRLLSDALEYNWQNQESLHYNDISTHVEHDQEQKYRPKLNSILPDYSSTHSNGNKHFFHQSKPQALIPELASKLLESCAKLKFNTRTLQILQNMISHVHGNILTTLSSSILPRHKSYLTRHNHPSHCKMIDSTLGHILRFVAASNPSEYFEFIRKSVQVPVTQTHTHSHSHSHSLPSSVYNSIVPHFDLFSFIYLSKHNFKKYLELIKNLSVTLRKTIYHCLLLHYSAKAIMFWIMARPAEYYELFNLLKDNNNEHSKSLNTLNHTLFEEIHSTFNVNSMITTNQNAHQGSSSPSSSSPSSPPSSSSSDNNNQ-----------------NIIAKSLSRQLSHHQSYIQQQSERKLHSSWTTNSQSSTSLSS--STSNSTTTDFSTHTQPGEYDPSLPDTPTMSNITISASSLLSQTPTPTTQLQQRLNSAAAAAAAAASPSNSTPTGYTAEQQSRASYDAHKTGHTGKDYDEHFLSVTRLDN-------VLELYTHFDDTEVLPHTSVLKFLTTLTMFDIDLFNELNATSFKYIPDCTMHRPKERTSSFNNTAHETGSEKTSGIKHITQGLKKLTSLPSSTKKTVKFVKMLLRNLNGNQAVSDVALLDTMRALLSFFTMTSAVFLVDRNLPSVLFAKRLIPIMGTNLSVGQDWNSKINNSLMVCLKKNSTTFVQLQLIFFSSAIQFDHELLLARLSIDTMANNLNMQKLCLYTEGFRIFFDIPSKKELRKAIAVKISKFFKTLFSIIADILLQEFPYFDEQITDIVASILDGTIINEYGTKKHFKGSSPSLCSTTRSRSGSTSQSSMTPVSPLGLDTDICPMNTLSLVGSSTSRNSDNVNSLNSSPKNLSSDPYLSHLVAPRARHALGGPSSIIRNKIPTTLTSPPGTEKSSPVQRPQTESISATPMAITNSTPLSSAAFGIRSPLQKIRTRRYSDESLGKFMKSTNNYIQEHLIPKDLNEATLQDARRIMINIFSIFKRPNSYFIIPHNINSNLQWVSQDFRNIMKPIFVAIVSPDVDLQNTAQSFMDTLLSNVITYGESDENISIEGYHLLCSYTVTLFAMGLFDLKINNEKRQILLDITVKFMKVRSHLAGIAEASHHMEYISDSEKLTFPLIMGTVGRALFVSLYSSQQKIEKTLKIAYTEYLSAINFHERNIDDADKTWVHNIEFVEAMCHDNYTTSGSIAFQRRTRNNILRFATIPNAILLDSMRMIYKKWHTYTHSKSLEKQERNDFRNFAGILASLSGILFINKKILQEMYPYLLDTVSELKKNIDSFISKQCQWLNYPDLLTRENSRDILSVELHPLSFNLLFNNLRLKLKELACSDLS--IPENESSYVLLEQIIKMLRTILGRDDDN-------YVMMLFSTEIVDLIDLLTDEIKKIPAYCPKYLKAIIQMTKMFSALQHSEVNLGVKNHFHVKNKWLRQITDWFQVSIAREYD-FENLSKPLKEMDLVKRDMDILYIDTAIEASTAIAYLTRHTFLEIPPAASDPELSRSRSVIFGFYFNILMKGLEKSSDRDNYPVFLR-------------HKMSVLNDNVILSLTNLSNTNVDASLQFTLPMGYSGNRNIRNAFLEVFINIVTNYRTYTAKTDLGKLEAADKFLRYTIEHP-----QLSSFGAAVCPASDIDAYAAGLINAFETRNATHIVVAQLIKNEIEKSSRPTDILRRNSCATRSLSMLARSKGNEYLIRTLQPLLKKIIQ----NRDFFEIEKLKPEDSD-AERQIELFVKYMNELLESISNSVSYFPPPLFYICQNIYK---------------------VACEKFP---DHAIIAAGSFVFLRFFCPALVSPDSENIIDIS-HLSEKRTFISLAKVIQNIANGSENFSRWPALCSQKDFLKECSDRIFRFLAELCRTDRTIDIQVRTDPTPIAFDYQFLHSFVYLYGLEVRRNVLNEAKHDDGDIDGDDFYKTTFLLIDDVLGQLGQPKMEFSNEIP--------IYIREHMDDYPELYEFMNRHAFRNIETSTAYSPSVHESTSSEGIPIITLTMSNFSDRHVDIDTVAYKFLQIYARIWTTKHCLIIDCTEFDEGGLDMRKFISLVMGLLPEVAPKNCIGCYYFNVNETFMDNYGKCLDKDNVYVSSKIPHYFINSN---SDEGLMKSVGITGQGLKVLQDIRVSLHDITLYDEKRNRFTPVSLKIGDIYFQVLHETPRQYKIRDMGTLFDVKFNDVYEISRIFEVHVSSITGVAAEFTVTFQDERRLIFSSPKYLEIVKMFYYAQIRLESEYEMDNNSSTSSPNSNNKDKQQKERTKLLCHLLLVSLIGLFDESKKMKNSSYNLIAATEASFGLNFGSHFHRSPEVYVPEDTTTFLGVIGKSLAESNPELTAYMFIYVLEALKNNVIPHVYIPHTICGLSYWIPNLYQHVYLADDEEGPENISHIFRILIRLSVRETDFKAVYMQYVWLLLLDDGRLTDIIVDEVINHALER---DSENRDWKKTISLLTVLPTTEVANNIIQKILAKIR-SFLPSLKLEAMTQSWSELTILVKISIHVFFETSLLVQMYLPEILFIVSLLIDVGPRELRSSLHQLLMNVCHSLAIN--SALPQDHRNNLDEISDIFAHQKVKFMFGFSEDKGRILQIFSASSFAS---------------------KFNILDFFINNILLLMEYSS-TYEANVWKTRYKKYVLESVFTSNSFLSARSIMIVGIMGKSYITEGLCKAMLIETMK-----------VIAEPKITDEHLFLAISHIFTYSKIVEGLDPNLDLMKHLFWFSTLFLESRHPIIFEGALLFVSNCIRRLYMAQFENESETSLISTLLKGRKFAHTFLSKIENLSGIVWNEDNFTHILIFIINKGLSNP----FIKSTAFDFLKMMFRNSYFEHQINQKSDHYLCYMFLLYFVLNCN--------QFEELLGDVDFEG------EMVNIENKNTIPKILLEWLSSDNEN-----------------------------------------------------------------------------------------------ANITLYQGAILFKCSVTDEPSRFRFALIIRHLLTKK---------------------PICALRFYSVIRNEIRKISAFEQNSDCVPLAFDILNLLVTHSESNSLEKLHEES---------IERLTKRGLSIVTSSGIFAKNSDMMIP-------------------------------------------------------------------------------------------------LDVKPEDIYERKRIMTMILSRMSCSA--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .:.: . : . . . . .*:: ** : **..: :*: :.: . . . : : . : :. ::. . :* :: .:. : :. : . :* :: .: . *. * :* . :. . .::*:..* :. ::.: *: .. * :: **: *: * :: * . : : * : . : . : : . .. ... : .*: : *. * * .. : . :: : . . .. . : . : ::*: * : : .*: : .. ::. : . . ** *:: * * . . .: . :* : * : . * . . .*:. . : * . : * .: .::* . : : : : .*:.:. : : :. : ::* : * * .. : .:...::. : :: : *: :. ::: :*:*:.* . : ::* : . * :: : :: : : :: . :: . : * . *: . .. . . :: :: : :: : * :. : . ..* * : . . * : *: *: .:.:::*: :..: : . . :.: : :: : .: : * ::::. *: . : :** ::: : .: : : .: . ::*: * :::.:*. . : :. :: : * . : :: :: ::...: . :*.. :.::.:** :. :***. : : *. **:* :::. .:. * .. :* ::* :* **.::*: *:.. : .: ::: *.. .:*:::** .:*:*:.* .:: :** : : * :*:**: :*: : : : :: : ::::. . :: * * . *: * * *:. *:::: :: ::: .*:* :. ::* ** .:: ::: : * ** *:**:: :: :. **:: : : :: *.: . :: :..: :* .* . **. * :*: :*: * .::** :: * *.*: :****: **:*** . .*:* . :* : ::*::*.*** *:: : :**::. : **: ::. . * :: . : ** ::: .: .: ... * . . : .* : :*. ** *: : . : .: *: : * .:::: .: . : .**. * *:: .:. . : * : *:.: . . :::* *. .. .*:. : ::* .* .* . * :* * :: :* * :: . :... *::. :: :. :.. * : :*::* : :.* ... * *::*:* .*: : * :**:* *.* *: : . . :**::: :: : :. .: ::: .: .. . *.*:* . : : ..: ** ::*:.* . . .::.::***:.* .:*.*:: .:: .: : :* :.* *: :.:.** .:*.** :: :..:... * :: : :: *: ** :. ** : .:: *: ** ::: :.:: . :* : : * *:::*..:: : . : . .* *: . *:.::* :: : : . *.:::** : : : *:..* * :* ::. :::*: *. .:*:* * *::*: ***. :.:: :. * *: *. ::**:*: *. : * :* : *: . : :* :** . * :.. . .* *. *..*:::: * :.* : : : * . : .* : :: ::: * : : : ***.: .*: . :: .. ::.: :: * :.. : ..:: *: . . .:::: *: : .** . *: : ** :* . :: . : : . : : . . :.*: * * : :: . : . : . . :. :*:. .* : . : * : *.* * .:.:: .:: .: :. :: : .*:: :: .: . : . : .: : : :..: : :: :. : :: * . : ", "identical_positions": 305, "similar_positions": 913, "identity": "8.78%" }, { "cls_id": "homologset.agr.SGD:S000005444", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0AB32TIS3-1", "uniprot_id": "A0AB32TIS3_DANRE", "id": "A0AB32TIS3-1", "name": "", "aln": "MSSWWGQLSESVNNSTVRLDNTSCFSSTQSTVLKGVNFGGIPVVLLLDFTVFILLLSIFTLIRRKLWDYGRLALVAETDVFGDGRKRRYSRLTSSMS-------------------------VEEPEYEKGCCSWLTFIVNMDETLVQERCGVDAVHYLSFQKHLVTLLLIICVLSVSIILPVNLSGDLLG--TDPYNFGRTTIGN---LQHDDKLLWLHTVFAVLYLMITVFLLRRYTSKMKGTKR--EIVRNTLFVRPLPRTSTDDSIKTHFMEAYPSCHVTSVNLCYDVAKLIDVNKNRKRAEKNLRHYNRILQQLGRRELINPRPCSHLCCCCQRCQGCEEVDAIEFYSSQEAALHEEEVRLKQGEL-HPLGMAFVTLQNEYMATYILKDFNALECGGGARGVVGEEMSRGIKCGCGREPQPSTRSAELGVPKWKVNYASHPHNIYWENLSVRGWRWLLRCVLLNTALFVLLFFLTTPSIIISTMDKF----------NVTMPIYYLNSPIISQFFPTLMLWTFSALLPTIVYYSTLGEAHWTRSSENMSMMYKLYTFLIFMVLILPSLGLTSLAVFFRWLFDKQSEGQLRFECVFLADQGAFFVNYVIAAALVGSGMELLRLPGLLLYIVRLALASSAAERKYVKQNQAYEFQYGAMYGWTLCVFTVIMAYSIVCPLIVPFGLLYLLLKHLVDKHNLYFAYLP-ARLDRQVHLGAVNQALAAPIICLIWLYFFSVLRTGFMTGTSLFTLVVLCITVFICISYTCFGHFKYLSPHNYNVK-----------------------------EEDEDADIVSENSSGLVYLPKVLNPDASFESSDECSPSHSYG--TTDISPQFIGTEESSPDSDI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6NP91-1", "uniprot_id": "TM63_DROME", "id": "Q6NP91-1", "name": "Mechanosensitive cation channel Tmem63", "aln": "-----MVMSENSN-------ISYCQAVANRTSFFTTAYNGIPETLILNTIFWVLLILLFTVLRHQAGDFGRLALVNSNGSKKRWTEIFYSRAASVVDPQPSTSTQVSPRPSTTSQGVPDSTPLSPIQPEEGLFGWIRVTLKLRKETILLHTGPDAVHYLSFQQHLMAVMALVTIVSLVIILPVNFLNGPKENPYDVNAFGRTTMAN---LSPDSPWLWVHTIITILYIPLVVLIMRR-ASGRNAFKK--AATRTIMISNISSSDRNKTVVRNYMQELFPDVTIENVSIAYNISRLYVRNAEFERVHEARLYCEHHRNRD--TLMVKPEMCS-----------CKKENAYEYYQREERKLSGDVARLRASTMNEPLDIAFITVSTVQEAQNIVTHFTPGTYR-----------------------------------QWHLVFAPSPDDLFWENLNVNKSHWYLKFFCVNAVLFLVLFFLSTPAMVVSLLNSR----------PWVKETEGKISPLVADFLPTLMLWTLSALMPVIVAISDKWMRHYTRSKQNYSIMTKCFGYLLMMIMILPSLGLTSAQALLEWGFLNQTD---RWQCIFLPDRGSFYVNYIITAAFIGTALELLRFPELIVYIWSLLKAKSKAETPYIRKAILIEFPFGTHYAWTTLVFTIAIVYSVACPLIMPFAMIYICLKHFVDRHNLYFAYGP-SNMISRKGGKIHSTAVTMTKFSVVILVLVMAMICFFRGDNGMARFLLLIISLAITLT-----LFTFMSPIKRCAA-----------------------------TRR--PSIVEIAGPAPIYVPDVLK-DNGIRTSSVRPSAAAFGGYGSDSVSEYDSSQYSVNSVEA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12252-1", "uniprot_id": "PHM7_YEAST", "id": "Q12252-1", "name": "Phosphate metabolism protein 7", "aln": "-------MADSSS---------------------TSAFISTLIIYGLTAVVFVWLFLLLRPKNRRVYEPRSLKDIQTIPEEER-----------------------------------------TEPVPEGYFGWVEYLLSKPHSFLIQHTSVDGYFLLRYIGIVGSLSFVGCLLLLPILLPVNATNGNNLQGFELLSFSNVTNKNRFYAHVFLSWIFFGLFTYVIYKELYYYVVFRHAMQTTPLYDGLLSSRTVIVTELHKSIAQEGEMQMRFPKASNVAFAYDLSDLQELCKERAKNAAKYEAALNKVLNKCVKMTRNKTQKQLDKLYNN---------GTKPKDDLETYVPHKKRPKHRLGKLPLCLGGKKVNTLSYSSKRIGELNEEIHEKQADWASNDRQPACFIQFETQLEAQRCYQSVEAILGKK---NFGKRLIGYSPEDVNWGSMRLSSKERHSRRAVANTIMVLLIIFWAFPVAVVGIISNVNFLTDKVPFLRFINNMPTFLMGVITGLLPTIALVVLMSLVPPFIVMLGKLSGCVTR--QETDLYSQAWYYAFAVIQIFLVVTATSSASSTVDSIIDRPRSAMTLLANNLPKASNFYIMYFILKGLTGPTWTILQAVNLLLSKVLGRVLDSTPRQKWNRYNTLATPRMGIVYPGIEILVCIYICYSIIAPILLFFSTVMLTLLYVAYLYNLNYVFGFSFDLKGRNYPRALFQIFVGIYLSEVCLLGLFIMAKTWGPLVLEVFWIVVTALAHIYMKRKFIPLFDAVPLSAIRHARGEPGYSYPTSDLGLQEIKDIADEMKGKYEQDNTHGILTPVTKDDLKKANLIPDNDGSSENGTPSNPFESGSERASLSGSNAESDSIKKLNDTVIKKSSTLSSSTKDNNESTFVPEGEKFRKFHYSDVEALRNKRPYDEDDHSKHGPEGAVPVNADAGVIYSDPAAVMKEPQAFPPDVLETNTWTRRILQFFNPRRSYPFDSVRMRFPLVFNTSIEYDEEYLSSAYTDPCVREKDPIVWCCKDPLGVSKQQIQEARSNGLDVRDDFTRYDEKGKVIFTYNPPDYEPEAKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::. . : . * .:: *: :: .:: : * : :* .*: :. . : : . *. . * : : :: : :: : *:**** .. : *...* * ::. . ::* : :: * : . *. :. . . :: : : .:. ::.: * .. : . . : : * * .: :* . :. : . : . . : . *.:: * .: : . : *: :.::::* : * ::. :.. ::: ::**: * .: :*:* :: ** :: .: : : : : :: *: : ** : .:. . *.. . *:: *.* .: *. :*: *:: .* .. : : * * :. : : **: .*::: *. : : * :.. :** :.: : : .. :. : * . : : ::: * :. * :. . .*: : ..:: : . .. . . * :. . :: : ", "identical_positions": 59, "similar_positions": 216, "identity": "5.49%" }, { "cls_id": "homologset.agr.SGD:S000005447", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KAW5-1", "uniprot_id": "A0A0G2KAW5_RAT", "id": "A0A0G2KAW5-1", "name": "WD repeat-containing protein 48", "aln": "----MAAHHRQNTAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCN-------GKTLISASSDTTVKVWNAHKGFCMS---TLRTHKDYVKALAYAKDKE--------------------------------LVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLA-----------MNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLK-GHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIAT----------YRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKSTVNKWTLKGIH--NFRASGDYDNDCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLG--KVDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITLD--ESDCFAAWVSAKDAGFS-SPD-GSDPKLNLGGLLLQALLEYWPRTHVTPMDEEENEVNH-----------------VSGEQESRVQKGNGYFQVP---------------------------------------------------------------------------------------------------PHTPVIFG---------------------------------------------------------------------------------------------------------------------------------------EAGGRTLFRLLCRDSGGETEAM----------------------------------------------LLNETVPQWVIDITVD--KNMPKFNKIPFYLQPHASSG-----AKTLKKDRLSASDMLQVR-----------------KVMEHVYEKIINLDNESQTTSSSN----------------------------NEKP-EQEKE-EDIAVLAEEKIELLCQDQVLDPNMDLRTVKHFIWKSGGDLTLHYRQKST--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH57-1", "uniprot_id": "WDR48_MOUSE", "id": "Q8BH57-1", "name": "WD repeat-containing protein 48", "aln": "----MAAHHRQNTAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCN-------GKTLISASSDTTVKVWNAHKGFCMS---TLRTHKDYVKALAYAKDKE--------------------------------LVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLA-----------MNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLK-GHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIAT----------YRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKSTVNKWTLKGIH--NFRASGDYDNDCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLG--KVDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITLD--ESDCFAAWVSAKDAGFS-SPD-GSDPKLNLGGLLLQALLEYWPRTHVTPMDEEENEVNH-----------------VSGGQESRVQKGNGYFQVP---------------------------------------------------------------------------------------------------PHTPVIFG---------------------------------------------------------------------------------------------------------------------------------------EAGGRTLFRLLCRDSGGETEAM----------------------------------------------LLNETVPQWVIDITVD--KNMPKFNKIPFYLQPHASSG-----AKTLKKDRLSASDMLQVR-----------------KVMEHVYEKIINLDNESQTTSSSN----------------------------NEKP-EQEKE-EDIAVLAEEKIELLCQDQVLDPNMDLRTVKHFIWKSGGDLTLHYRQKST--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TAF3-1", "uniprot_id": "WDR48_HUMAN", "id": "Q8TAF3-1", "name": "WD repeat-containing protein 48", "aln": "----MAAHHRQNTAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCN-------GKTLISASSDTTVKVWNAHKGFCMS---TLRTHKDYVKALAYAKDKE--------------------------------LVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLA-----------MNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLK-GHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIAT----------YRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKSTVNKWTLKGIH--NFRASGDYDNDCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLG--KVDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITLD--ESDCFAAWVSAKDAGFS-SPD-GSDPKLNLGGLLLQALLEYWPRTHVNPMDEEENEVNH-----------------VNGEQENRVQKGNGYFQVP---------------------------------------------------------------------------------------------------PHTPVIFG---------------------------------------------------------------------------------------------------------------------------------------EAGGRTLFRLLCRDSGGETESM----------------------------------------------LLNETVPQWVIDITVD--KNMPKFNKIPFYLQPHASSG-----AKTLKKDRLSASDMLQVR-----------------KVMEHVYEKIINLDNESQTTSSSN----------------------------NEKPGEQEKE-EDIAVLAEEKIELLCQDQVLDPNMDLRTVKHFIWKSGGDLTLHYRQKST--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A9S1-1", "uniprot_id": "A0AB13A9S1_DANRE", "id": "A0AB13A9S1-1", "name": "WD repeat-containing protein 48", "aln": "----MATHHRQNAAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCN-------GKTLISASSDTTVKVWNAHKGFCMS---TLRTHKDYVKALAYAKDKE--------------------------------LVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLA-----------MNQMGTVIVSGSTEKVLRVWDPRTCAKLMKLK-GHTDNVKSLLLNRDGTQCLSGSSDGTIRLWSLGQQRCIAT----------YRVHDEGVWALQVNEAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKMELDRSADPHNAIWVSTTKSTVNKWSLKGIH--NFRASGDYDNDCSAPLTPLCTQPEQVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLG--KMEFDEEIKKRFKMVYVPNWFSVDLKTGMLTITLD--ESDCFAAWVSAKDAGFS-SPD-GSDPKLNLGGLLLQALLEFWPRTHINPMD-EETELNHS---------------SVNGEHESRIQKGNGYFQVP---------------------------------------------------------------------------------------------------PHTPVIFG---------------------------------------------------------------------------------------------------------------------------------------EAGGRTLFRLLCRDSGGETESM----------------------------------------------LLNETVPQWVIDITVD--KNMPKFNKIPFYLQPHSSSG-----AKTLKKDRLSASDMLQVR-----------------KVMEHVYEKIINLDSESQTGGSAA----------------------------EKPSSEQKED-EEMAVQAEEKIELLCQDQVLDPNMDLRTVKHFIWKSGGDLTLHYRQKST--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6PFM9-1", "uniprot_id": "WDR48_DANRE", "id": "Q6PFM9-1", "name": "WD repeat-containing protein 48", "aln": "----MATLHRQNAAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIILCCN-------GKTLISASSDTTVKVWNAHKGFCMS---TLRTHKDYVKALAYAKDKE--------------------------------LVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLA-----------MNQTGTVIISGSTEKVLRVWDPRTCAKLMKLK-GHTDNVKSLLLNRDGTQCLSGSSDGTIRLWSLGQQRCIAT----------YRVHDEGVWALQVNEAFTHIYSGGRDRKIYCTDLRNPDMRVLICEEKAPVLRMELDRSADPPQSIWVSTTKSFVNKWSLKAMH--NFRASGDYDNDCSAPLTPLCTQPEQVIKGGTSIVQCHILNDKRHILTKDTNNSVAFWDVLKACKGEDLG--KVDFDEEVKKRFKMVYVPNWFSVDLKTGMLTITLD--ESDCFAAWVAAKDAGFT-SPD-GSDPKLNLGGLLLQALLEFWPRTHINPMEEEENELNH-----------------VNGEQESRIQKGNGYFQVP---------------------------------------------------------------------------------------------------PHTPVIFG---------------------------------------------------------------------------------------------------------------------------------------EAGGRTLFRLLCRDSGGETESM----------------------------------------------LLNETVPQWVIDITVD--KNMPKFNKIPFYLQPHSSSG-----AKTLKKDRLSASDMLQVR-----------------KVMEHVYEKIINLDTESQATSSSA----------------------------NDKPGEQEKE-EDVSVMAEEKIELMCLDQVLDPNMDLRTVKHFIWKSGGDLTIHYRQKST--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1LZ08-1", "uniprot_id": "WDR48_DROME", "id": "Q1LZ08-1", "name": "WD repeat-containing protein 48 homolog", "aln": "----MLTHK--TCQARKKMQVSFVIRDAEEKQHRNGVNALQLDANNGKLYSAGRDAIIRVWNTRTDSSEKYIQSMEHHNDWVNDIVLCCN-------GRNLISASCDTTVKVWNAQKGFCMS---TLRTHRDYVQALAYAKDRE--------------------------------QVASAGLDKAIFLWDVNTLTALTASNNTVTTSSLTGSKDSIYSLA-----------MNPSGTVIVSGSTENILRIWDPRTCMRRMKLR-GHTENVRCLVVSPDGNQVVSGSSDGTIKVWNLGQQRCVQT----------IHVHKEGVWSLLMSENFQYIISGSRDRNIIVTEMRNPSNKTLVCEEQAPVLSLGYNIDKTG---VWATTWNSDIRCWKLPMYDRCTLNSSGGMDAQWTQGGTEVAC-----IKGGAAIKECAVLNDKRYIITKDSQDQVVVYDVLRVVKKEQLG--AVDFEAEVKKRNKQVYIPNWFTVDLKTGMPTIVLGQEEVDCFSAWVSIEAGLPE-CVDPTTEIKINYGKLLLEALLEYWTPPHSIPPNEMEPDMHG-----------------------------NGYFQVP---------------------------------------------------------------------------------------------------KHTPVIFS---------------------------------------------------------------------------------------------------------------------------------------EVGGRTVCRLLVRDAAGDSEST----------------------------------------------LLHETAPQWVTDVVIE--KNIPKFLKIPFFLQPHPQMTK----PERTKKDRLVANEFIQCR-----------------KVCEHVLEKVLNAETTPSGGNANN----------------------------SLQNSQSDANSEGSQLPAEERIELWCNDVVVDPNMDLRTVRHFIWKQSTDLTFQYKTKQNFNYDGK--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99247-1", "uniprot_id": "DUF1_YEAST", "id": "Q99247-1", "name": "DUB-associated factor 1", "aln": "MNQLTVSYGLISPDYCTSQDAHILPITKILYPDIPGKNYFLTSGRDGSIILHKNTQLSNEPETAATTIKNDAIRMQVHSDWASDLIHVNMKNSDPSAGDTFISVSHDFSIVLISVNAQLTTWDKKIIGDHDDYIKCIVPIHYEMSNDYELEEQEGGPDNVHDGINNGIVVDEQNNFLFVTGGLDRKIKLWCLSSGPEKMATLLHTFDNAQSNDTGSIYSMSPIIPKYSFDDNQTSRPFDFVAGDCNGDLIFYSCKYRKEVIRIQNAHRTNIKVVRTLDDSTRLISTSSDGVINVWDLNCRHDQTTGALQLPKKIGSWSWDSSIWCVQG-TSLDKLYFGDSQGNVMRANLSSYEDAKLTRIFKPDHHHHHHHHHEHEEQNISTTDAKVKKYGGILDIALLPNEKLLFSFCTDSNLNVLDLTNNHFSVNEGGFALTRSSLLTNRRHVITENTKGQMQRWDIVSCELLNTFDSSEGSFDDIVMKYTSKEILSHWCTVSVKVGMLFVKINPKFLKTEVYGSALKDYQVVNNIEINSDERYNLGKIVINSLFNEFISYEVQKDKLLRKKIFSLKKKDLTNSLTLDTGYNSESKKNNKDKKRKSTFKISSTLSIGNTNSSGTPPNSAPATPVMAETIVLEEQPLLQSASDKAIDDSLELVQPLPASKKPYFRTQSSGSLLSRKFKSFRSTSGRATTGLNTPEEPKGILPDTPHVINDDSAFPQAINTTQQSKDATPESMLWNHPFKLEQKLSAISSQDLPSNNTHNKLRSSENSRANSTSTLEGNEKKKPEFMPDLLEQIQESYKQQYMNTSSLKYLTKRLPVTKIIKASSCPIIRVKSATLVLVHLWKEGSCGGRVLFSTLLPPSHVDNETVSGGKENSKPPDDEEVDLQAVDDDKLGKYDLIDGELGSRLNRRQIFEQLEENLPYWFAKALFRDIKTVEEQPKLNFLIMPWSSVGGSEAAGNENKKKFISASDTTESSGNDSSDSSLGNGNEAVSPSTQQQFHNMLKFGRPKTSEQELNPTDLPRISEANVKLVAPGMIRVKKIKLYVADRFETKTPEMKAKMEPSLWLDLLCRGQVLDNDMTLNTVRTLYWKSQGDIVLEYRRKVHNSPLVHEVNGNEGK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . :. : . * * : . . : . : . .. . . *: *.**..*:: * .:**.* * :: : ..: : : * **::.:. : . ..:.***: * ** :.: . *: . .: :....****:: . :::*. : * .:. : . :::: .* *:: : *..: :* ****.*.:*.*. :: * ...:*.: : : *. : :: ::: . . * :. . : .: : * . . . : . : :** :: .. :*.::*:::*::::..: :*:: : :. .*: : * . :.:* :*.:*.** : :. . : : : :: : * * :::::*:: : . . . .: :. *::. .** ::. . ***.: * : :.*: *.*. * *. . . *.: : *: * : * .. : **. : *.: : :: .:::: : . : .. ::* * . *:* :* *.**: : **. *:.:.*: * ", "identical_positions": 92, "similar_positions": 241, "identity": "8.24%" }, { "cls_id": "homologset.agr.SGD:S000005450", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54275-1", "uniprot_id": "MSH2_RAT", "id": "P54275-1", "name": "DNA mismatch repair protein Msh2", "aln": "MAVQPKE-----TLQLEGAAEVGFVRFFEGMPEKPSTTVGLFDRGDFYTAHG-EDALLAAREVFKTQGVIK--YMGPAGAK----TLQTVVLSKMNFESFVKDLLLVRHYRVEVYKNKAGNKASKENDWYLAYKASPGNLSQFEDILFGNNDMATSIGIMGIKLSTVDG-QRQVGVGDVDSTQRKLGLCEFPDNDQFSNLEALLIQIGPKECILPGGETAG----DMGKLRQVIQRGGILITERKRIDFSTKDIYQDLNRLLKGRKGEQMNSAVLPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELATFDFSQYMKLDMAAVRALNLFQGSVEDTTGS-----------------QSLAAFLNKCKTAQGQRLVSQWIKQPLMDKNRIEERLNLVEAFVEDSELRRALQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGVKQLPNVIQALEKYQGRH------QALLLAVFVTPLTDLRSDFSKFQEKIETTLDMDQVE-NHEFLVKPSFDPNLSELREVMDGLEKKMQSTLISAARGLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTVDIQKNGVKFTNSELSSLNEEYTKNKGEYEEAQDAIVKEIVNISSGYVEPMQTVNDVLAHLDAVVSFAHVSNAAPVPYVRPVILEK-GKGRIIVKASRHACVEVQHDVAFIPNDVHFEKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATNIGAFCMFATHFHELTALASQIPTVNNLHVTALTT---------EETLTMLYQVKTGVCDQSFGIHVAELANFPRHVIECAKQKALELEEFQSIGTSQGHDET--QPAAKRRCLEREQGEKIILEFLSKVKQVP---FTDLSEESVSVKLKQLKAEVLAKNNSFVNEIISRVKAP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43247-1", "uniprot_id": "MSH2_MOUSE", "id": "P43247-1", "name": "DNA mismatch repair protein Msh2", "aln": "MAVQPKE-----TLQLEGAAEAGFVRFFEGMPEKPSTTVRLFDRGDFYTAHG-EDALLAAREVFKTQGVIK--YMGPAGSK----TLQSVVLSKMNFESFVKDLLLVRQYRVEVYKNKAGNKASKENEWYLAFKASPGNLSQFEDILFGNNDMSASVGVMGIKMAVVDG-QRHVGVGYVDSTQRKLGLCEFPENDQFSNLEALLIQIGPKECVLPGGETTG----DMGKLRQVIQRGGILITERKRADFSTKDIYQDLNRLLKGKKGEQINSAALPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELATFDFSQYMKLDMAAVRALNLFQGSVEDTTGS-----------------QSLAALLNKCKTAQGQRLVNQWIKQPLMDRNRIEERLNLVEAFVEDSELRQSLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPSVIQALEKYEGRH------QALLLAVFVTPLIDLRSDFSKFQEMIETTLDMDQVE-NHEFLVKPSFDPNLSELREVMDGLEKKMQSTLINAARGLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTVDIQKNGVKFTNSELSSLNEEYTKNKGEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAHLDAIVSFAHVSNAAPVPYVRPVILEK-GKGRIILKASRHACVEVQDEVAFIPNDVHFEKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISDYIATKIGAFCMFATHFHELTALANQIPTVNNLHVTALTT---------EETLTMLYQVKKGVCDQSFGIHVAELANFPRHVIACAKQKALELEEFQNIGTSLGCDEA--EPAAKRRCLEREQGEKIILEFLSKVKQVP---FTAMSEESISAKLKQLKAEVVAKNNSFVNEIISRIKAPAP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43246-1", "uniprot_id": "MSH2_HUMAN", "id": "P43246-1", "name": "DNA mismatch repair protein Msh2", "aln": "MAVQPKE-----TLQLESAAEVGFVRFFQGMPEKPTTTVRLFDRGDFYTAHG-EDALLAAREVFKTQGVIK--YMGPAGAK----NLQSVVLSKMNFESFVKDLLLVRQYRVEVYKNRAGNKASKENDWYLAYKASPGNLSQFEDILFGNNDMSASIGVVGVKMSAVDG-QRQVGVGYVDSIQRKLGLCEFPDNDQFSNLEALLIQIGPKECVLPGGETAG----DMGKLRQIIQRGGILITERKKADFSTKDIYQDLNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYMKLDIAAVRALNLFQGSVEDTTGS-----------------QSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKH------QKLLLAVFVTPLTDLRSDFSKFQEMIETTLDMDQVE-NHEFLVKPSFDPNLSELREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPYVRPAILEK-GQGRIILKASRHACVEVQDEIAFIPNDVYFEKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTALANQIPTVNNLHVTALTT---------EETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAKQKALELEEFQYIGESQGYDIM--EPAAKKCYLEREQGEKIIQEFLSKVKQMP---FTEMSEENITIKLKQLKAEVIAKNNSFVNEIISRIKVTT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43248-1", "uniprot_id": "MSH2_DROME", "id": "P43248-1", "name": "DNA mismatch repair protein spellchecker 1", "aln": "MQAKATDSRQEPTLNMDTNARRNFIKFHAKLGEKPATTVRFFDHTDRYTVHGSDDCELVAKIVYKSTAFIG--ALLPDDKKE---TLQFVSMSKGNFELAVRELLLVRNYRVEVYVKNS-------SDWEIEYRGSPGNLLQFEDILFSNKEVLVGNSIISLLVKLDGGGQRRVGVASVEQNDCKFQLLEFLDDDFFTELEATVVLLGPKECLLP--SIEG----EYSAVKTLLDRNGVMITMPKKS--GDNDLLQDLNRLLRFAKGQQEDATGLKELQLQLASNALKTAIKYLDLVNDAGNLGHYEIKQLDLNRFVHLDSAAVAALNIMPKPGTHPSMPS-------------YRWQSVLGVLDHCRTPQGHRLMGQWVKQPLRSRNILNDRHNIVQCLLESPDTMETLSLDYLKRIPDILMLTKKLMRRKANLQDLFRIYQVILRTPKILKVLHELDN---------STIESVICAPFKSFLKDLTGLKQMVEQVVDFEAIE-RGEYLVKASFDSRLMELQQMMTELYSKMEELQFKCSQELNLDGKNQVKLESVAKLGHHFRITVKDDSVLRKNKNYRIVDVIKGGVRFTSDKLEGYADEFASCRTRYEEQQLSIVEEIIHVAVGYAAPLTLLNNELAQLDCLVSFAIAARSAPTPYVRPKMLEE-GARELVLEDVRHPCLELQEHVNFIANSVDFKKEECNMFIITGPNMGGKSTYIRSVGTAVLMAHIGAFVPCSLATISMVDSILGRVGASDNIIKGLSTFMVEMIETSGIIRTATDKSLVIIDELGRGTSTYEGCGIAWSIAEHLAKETKCFTLFATHFHEITKLAETLSTVKNCHMAAVAD---------ADDFTLLYQVRSGVMEKSFGIQVARLANFPEHVVQNAQEVYNEFED---------------EHVDKQKKEDKALLEKIQVAIQQLSTAGN---NVDINVEDLTQLVTQFTKDIEQLDSDYFKSVLATSEA---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25847-1", "uniprot_id": "MSH2_YEAST", "id": "P25847-1", "name": "DNA mismatch repair protein MSH2", "aln": "MSSTRPE-----LKFSDVSEERNFYKKYTGLPKKPLKTIRLVDKGDYYTVIG-SDAIFVADSVYHTQSVLKNCQLDPVTAKNFHEPTKYVTVSLQVLATLLKLCLLDLGYKVEIY----------DKGWKLIKSASPGNIEQVNELMNMNIDSSIIIASLKVQWNSQDG-NCIIGVAFIDTTAYKVGMLDIVDNEVYSNLESFLIQLGVKECLVQDLTSNSNSNAEMQKVINVIDRCGCVVTLLKNSEFSEKDVELDLTKLLG-----DDLALSLPQKYSKLSMGACNALIGYLQLLSEQDQVGKYELVEHKLKEFMKLDASAIKALNLFPQGPQNPFGSNNLAVSGFTSAGNSGKVTSLFQLLNHCKTNAGVRLLNEWLKQPLTNIDEINKRHDLVDYLIDQIELRQMLTSEYLPMIPDIRRLTKKLN-KRGNLEDVLKIYQFSKRIPEIVQVFTSFLEDDSPTEPVNELVRSVWLAPLSHHVEPLSKFEEMVETTVDLDAYEENNEFMIKVEFNEELGKIRSKLDTLRDEIHSIHLDSAEDLGFDPDKKLKLENHHLHGWCMRLTRNDAKELRKHKKYIELSTVKAGIFFSTKQLKSIANETNILQKEYDKQQSALVREIINITLTYTPVFEKLSLVLAHLDVIASFAHTSSYAPIPYIRPKLHPMDSERRTHLISSRHPVLEMQDDISFISNDVTLESGKGDFLIITGPNMGGKSTYIRQVGVISLMAQIGCFVPCEEAEIAIVDAILCRVGAGDSQLKGVSTFMVEILETASILKNASKNSLIIVDELGRGTSTYDGFGLAWAIAEHIASKIGCFALFATHFHELTELSEKLPNVKNMHVVAHIEKNLKEQKHDDEDITLLYKVEPGISDQSFGIHVAEVVQFPEKIVKMAKRKANELDDLKTNNEDLKKAKLSLQEVNEGNIRLKALLKEWIRKVKEEGLHDPSKITEEASQHKIQELLRAIANEPEKENDNYLKYIKALLL----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : . .* : . : :** .*: :.*: * **. * .*. :.* *::: ..: : * * : * :* : :: ** *:**:* . * : .****: *.:::: * : . : : .* : :**. :: *. : :: ::: :::**: :: :* ***:: . : : :::* * ::* *. . :*: **.:** : : * : ::: .: .: * :*:*:.: .:.*::*: .:..:::** :*: ***:: .. . *: .*::*:* * **:.:*:**** . : ::.* ::*: :::. : . * : * :**: *:**: : .**:* ::** : *.:::.: . : :* :*: . :: ::: :* .:*:: * . *:::* .*: .* :::. : * .::.. :..:. *.:* :::**:. * :*:* :: . **::*:: :. * *: *:..:* . :* : .*:: * ::*.**:::: *. : :. **:** :.*** .: ** **:** : . . : **. :*:*..: **.*.* ::. : : ***************..*. ***:**.****. * :::**.** ****.*. :**:****.*::**:.*::.*:..**:*:**********:* *:**:*::::*.: .* :*******:* *:. :..*:* *:.* : :*:**:*. *: ::****:**.:.:**.::: *:. *::: : . : : :: . . . ..: : : : :..:.: : : ", "identical_positions": 234, "similar_positions": 349, "identity": "23.61%" }, { "cls_id": "homologset.agr.SGD:S000005452", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BMY1-1", "uniprot_id": "LAAT1_RAT", "id": "B0BMY1-1", "name": "Lysosomal amino acid transporter 1 homolog", "aln": "--MVWRTLVASNFST-CPNGSIQWIWDVFGECAQDGWDEASVALGLVSIFCFAASTFPQYIKACKTGNMDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLLMLTLYFHYKFKKQPSLL------SAPINSV-LLFILG------TVCITPLLSSTDPVAVPREGFRG-------------RTLLSVE------------------------PGN---KPFTKKEVVGFVIGSASSVLYLLSRLPQIRTNFVRQSTQGISYSLFALVMLGNTLYGLSVLLKNPEVGQSEGSYLLHHLPWLVGSLGVLLLDTIISIQFLVYRSHDADAAS---EREPLLPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C4N4-1", "uniprot_id": "LAAT1_MOUSE", "id": "Q8C4N4-1", "name": "Lysosomal amino acid transporter 1 homolog", "aln": "--MVWRTLGASNFST-CPNGSVQWIWDVFGECAQDGWDEASVGLGLVSILCFAASTFPQYIKACKTGNMDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLMMLTLYFHYKFKKRPSPL------SAPINSV-LLFILG------TVCITPLLSSTDPVAVPREGFRG-------------RTLLSVE------------------------PGN---KPFTKKEVIGFVIGSASSLLYLLSRLPQIRTNFIRQSTQGISYSLFALVMLGNTLYGLSVLLKNPEVGQSEGSYLLHHLPWLVGSLGVLLLDTIISIQFLVYRSHETAAAS---EREPLLPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZP29-1", "uniprot_id": "LAAT1_HUMAN", "id": "Q6ZP29-1", "name": "Lysosomal amino acid transporter 1 homolog", "aln": "--MVWKKLGSRNFSS-CPSGSIQWIWDVLGECAQDGWDEASVGLGLISILCFAASTFPQFIKAYKTGNMDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLVMLTLYFYYKFRTRPSLL------SAPINSV-LLFLMG------MACATPLLSAAGPVAAPREAFRG-------------RALLSVE------------------------SGS---KPFTRQEVIGFVIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGLSVLLKNPEEGQSEGSYLLHHLPWLVGSLGVLLLDTIISIQFLVYR--RSTAAS---ELEPLLPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UY59-1", "uniprot_id": "A0A8N7UY59_DANRE", "id": "A0A8N7UY59-1", "name": "Lysosomal amino acid transporter 1 homolog", "aln": "MSDGFELGGGGNFSSLCPNG-IAWIWYGLGECAQDGRDVASVVLGLLSIVCFMVSSIPQYYSSCKTGNMDSALSIWFLLFWLAGDSCNLIGSFLADQLPLQKYTAVYYVVADLLMLAMYMYYKLKNKRSSD------RALLNALSVLCLLG------MTSSLLSIPHWSLEDQMPSGFRG-------------RALLALE------------------------EDNGAVQPFKTREIIGFVIGSISSVLYLCSRLPQIYTNFQRKSTEGLSYFLFALVILGNTTYGVSVLLKNPDPGQGEASYMVHHLPWLIGSLGTLSLDLVISVQFMMYRKSPQVSADTDEERAALLQN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12010-1", "uniprot_id": "YPQ1_YEAST", "id": "Q12010-1", "name": "Vacuolar lysine transporter YPQ1", "aln": "---------------------MQLVPLELNRSTLSG------ISGSISISCWIIVFVPQIYENFYR-KSSDGLSLLFVVLWLAGDVFNLMGAVMQHLLSTMIILAAYYTVADIILLGQCLWYDNEEKPAVDPIHLSPANPINENVLHDVFNEQQPLLNSQGQPNRIDEEMAAPSSDGNAGDDNLREVNSRNLIKDIFIVSGVVFVGFISWYVTYCVNYTQPPPVEDPSLPVPELQINWMAQIFGYLSALLYLGSRIPQILLNFKRKSCEGISFLFFLFACLGNTTFIFSVIVIS-----LDWKYLIMNASWLVGSIGTLFMDFVIFSQFFIYKRNKKFILN-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :...: .* * :** *: .** . : ...**: *:: *:.** **:*:.: . *. *.**.:**:::* : *. . : : :* : ::. .. * : :: :. . * : :. ::* *::*** **:*** ** *:* :*:*: :* :. **** : .**:: . : .*:: : .**:**:*.* :* :* **::*: . ", "identical_positions": 62, "similar_positions": 86, "identity": "17.61%" }, { "cls_id": "homologset.agr.SGD:S000005453", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C1Z8-1", "uniprot_id": "TM10A_MOUSE", "id": "Q8C1Z8-1", "name": "tRNA methyltransferase 10 homolog A", "aln": "MSS-EMLPASIESPNVEEKLGTSDGEEERQEPRVDAGAEPISKRQLKKLMKQKQWEEQREQRKEKRKEKRKRKKLERR-QLESNSDGND---RKRVRR-----DVARSSLRLVIDCSFDDLMVLKDIKKLHKQIQRCYAENRRASHPVQFYLT--SHGGQLKKNMDENDQGWVNWKDIHIKSEH----YSELIKKEDLVYLTSDSPNVLKDLDESKAYVIGGLVDHSHHKGLTFKQATSYGIEHAQLPLADFVKMNSRKVLAVNHVFEIILEFLETRDWQEAFFTILPQRKGAVPAHKACESSPQDHQSL---PEGWDS-ASEGESCRDNPDSPQKDEQGQQSSPVLQ------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KLI2-1", "uniprot_id": "TM10A_RAT", "id": "Q4KLI2-1", "name": "tRNA methyltransferase 10 homolog A", "aln": "MSS-EVLPASIEPPNVEGKPGASDSEEERQKQRVDAEAQPISKRQLKKLMKQRLWEEQREQRKEKRKEKRKRKKLERRCQLESNSDGND---RKRIRR-----HVAPSNLRLIIDCSFDDLMVLKDIKKLHKQIQRCYAENRRASHPVQFYLT--SHGGQLKKNMDENDQGWVNWKDIHIKSEH----YSELIKKEDLVYLTSDSPNVLKDLDESKAYVIGGLVDHNHHKGLTFKQASSYGIKHAQLPLAEFVKMNSRKVLAVNHVFEIILEFLETGDWQEAFFTILPPRKGAVPAHKACESSPQDHQAL---PGGWDS-AIEGEHGRDDPGSPHKEQQGQQSSSVSAVSPDPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TBZ6-1", "uniprot_id": "TM10A_HUMAN", "id": "Q8TBZ6-1", "name": "tRNA methyltransferase 10 homolog A", "aln": "MSS-EMLPAFIETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEPNSDGHD---RKRVRR-----DVVHSTLRLIIDCSFDHLMVLKDIKKLHKQIQRCYAENRRALHPVQFYLT--SHGGQLKKNMDENDKGWVNWKDIHIKPEH----YSELIKKEDLIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVKMNSRKVLAVNHVFEIILEYLETRDWQEAFFTILPQRKGAVPTDKACESASHDNQSVRMEEGGSDSDSSEEEYSRNELDSPHEEKQDKENHTESTVNSLPH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FBE2-1", "uniprot_id": "E7FBE2_DANRE", "id": "E7FBE2-1", "name": "tRNA methyltransferase 10 homolog A", "aln": "MATGKADEPAVQESHHECANNENEPAKDEKDTLQTGEVETMSKRQRKKLLKSQQWEEQRELRKQKRKERKQQRKLERQAQGDDGVEWTG---KKRLRR-----SAEPSSLRLIIDCSFDNLMVLKDVKKLHKQIQRCYAENRRTLHPAQFYLT--SHGGQLKQIMDEINKGWVNWKDVHVKTDA----FHEILKKEDLVYLTSDSPNVLQELDENKAYVIGGLVDHNHHKGITFNLAQELGIAHAQLPLGSFVKMNSRKVLAVNHVFEIILAFLEKRDWREAFFTVLPQRKGAVPMGQENTLGKDEDEEESDDDSDSEHLSERRTDSKDQSDNKQDEEHKRVPNQPDSTDKNTE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VR56-1", "uniprot_id": "TM10A_DROME", "id": "Q9VR56-1", "name": "tRNA (guanine(9)-N(1))-methyltransferase Trmt10A", "aln": "-----------MDTTEKALKEVTPAMLSLNNCPGTTPGTPMSKNQLKKQRKLAEFAELRKLRREREREKKKQKRREAKELGLPVRTGPS---RKELKKRQL-ADGGKSGLSVAIDLDYDDLMQERDIVKCVKQCLRIYTINRRSPQPGNLHFTGIRRNGHIHESFKK-NEGWENWHVQYYFDRG----HTDIFEHSQLVYLTCESDRVLDKLQPGCTYVIGGLVDHNHFKGLCHSRATSAGLTTARLPLSEHVDMKTRAVLSTYHVFELLTKVAAGQDWTTAILETIPMRKGAKAKITDKKEPNHCLEQQD---------EKQKQEAESDKPTLTAVESEIESHSLDS------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12400-1", "uniprot_id": "TRM10_YEAST", "id": "Q12400-1", "name": "tRNA (guanine(9)-N1)-methyltransferase", "aln": "---------------MSNDEINQNEEKVKRTPPLPPVPEGMSKKQWKKMCKRQRWEENKAKYNAERRVKKKRLRHERSAKIQEYIDRGEEVPQELIREPRINVNQTDSGIEIILDCSFDELMNDKEIVSLSNQVTRAYSANRRANHFAEIKVAPFDKRLKQRFETTLKNTNYENWNHFKFLPDDKIMFGDEHISKDKIVYLTADTEEKLEKLEPGMRYIVGGIVDKNRYKELCLKKAQKMGIPTRRLPIDEYINLEGRRVLTTTHVVQLMLKYFDDHNWKNAFESVLPPRKLDAEAKSASSSPAPKDT----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :**.* ** * : * : . ..: :::: : * :: ::. * : : :* .:*.** ::: . :* * *: ***: : :: .: : : : : .: **: : :.:..::***.:: . *..*: . *::**:**:.:.* : . * . *: :**: ..:.:: * **:. **.::: :* *: :* ** ", "identical_positions": 46, "similar_positions": 89, "identity": "12.99%" }, { "cls_id": "homologset.agr.SGD:S000005454", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q641W4-1", "uniprot_id": "RFC2_RAT", "id": "Q641W4-1", "name": "Replication factor C subunit 2", "aln": "MEVQESGSGSAESGTQE--PSPVPSKT---TGHYELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAVLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGYINSENVFKVCDEPHPLLVKEMIQHCVDANIDEAYKIL-AHLWHLGYSPEDVIGNIFRVCKTFP-MAEYLKLEFIKEIGYTHMKVAEGVNSLLQMAGLLARLCQKTMAPVAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUK4-1", "uniprot_id": "RFC2_MOUSE", "id": "Q9WUK4-1", "name": "Replication factor C subunit 2", "aln": "MEVQESGCDPSESGAQE--PSPVPSKT---AGHYELPWVEKYRPLKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAVLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQVLTRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGYINSENVFKVCDEPHPLLVKEMIQHCVDANIDEAYKIL-AHLWHLGYSPEDVIGNIFRVCKTFP-MAEYLKLEFIKEIGYTHMKVAEGVNSLLQMAGLLARLCQKTMAPVAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35250-1", "uniprot_id": "RFC2_HUMAN", "id": "P35250-1", "name": "Replication factor C subunit 2", "aln": "MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKIL-AHLWHLGYSPEDIIGNIFRVCKTFQ-MAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N4C3-1", "uniprot_id": "A0A8M1N4C3_DANRE", "id": "A0A8M1N4C3-1", "name": "Replication factor C subunit 2", "aln": "MDVEMKETDSEQTQADGP-PKKDETAPKPTTTAYELPWVEKYRPLKLNEIVGNEETVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPAMKDAVLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYSKLRDEQIMMRLTEVVEKENLHVTNDGLEAIIFTAQGDMRQALNNLQSTNSGFGYINSENVFKVCDEPHPLLVKSMLEHCVNANIDEAYKII-EQLWSLGYSPEDIIGNIFRVCKTFQ-MAEYLKLEYIKEIGYTHMKVAEGVNSLLQMAGLLGRLCRKTATPEAS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53034-1", "uniprot_id": "RFC2_DROME", "id": "P53034-1", "name": "Replication factor C subunit 2", "aln": "MPEE------PEKTADD--------------KRSHLPWIEKYRPVKFKEIVGNEDTVARLSVFATQGNAPNIIIAGPPGVGKTTTIQCLARILLGDSYKEAVLELNASNERGIDVVRNKIKMFAQQKVTLPRGRHKIVILDEADSMTEGAQQALRRTMEIYSSTTRFALACNTSEKIIEPIQSRCAMLRFTKLSDAQVLAKLIEVAKWEKLNYTEDGLEAIVFTAQGDMRQGLNNLQSTAQGFGDITAENVFKVCDEPHPKLLEEMIHHCAANDIHKAYKIL-AKLWKLGYSPEDIIANIFRVCKRIN-IDEHLKLDFIREIGITHMKIIDGINSLLQLTALLAKLCIAAEKH---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40339-1", "uniprot_id": "RFC4_YEAST", "id": "P40339-1", "name": "Replication factor C subunit 4", "aln": "MSKTLS---------------------------LQLPWVEKYRPQVLSDIVGNKETIDRLQQIAKDGNMPHMIISGMPGIGKTTSVHCLAHELLGRSYADGVLELNASDDRGIDVVRNQIKHFAQKKLHLPPGKHKIVILDEADSMTAGAQQALRRTMELYSNSTRFAFACNQSNKIIEPLQSRCAILRYSKLSDEDVLKRLLQIIKLEDVKYTNDGLEAIIFTAEGDMRQAINNLQSTVAGHGLVNADNVFKIVDSPHPLIVKKML---LASNLEDSIQILRTDLWKKGYSSIDIVTTSFRVTKNLAQVKESVRLEMIKEIGLTHMRILEGVGTYLQLASMLAKIHKLNNKA---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .***:***** :.:****::*: **. :* :** *::**:* ** ****:: ***: *** : :.:******::********:** ***:*: ** *:***:********* ***********:**.:****:*** *:*****:*****:**::** * ::: :* :: : * : *:******:***:*****.:****** *.* :.::****: *.*** :::.*: ::..: :*: .** ***. *:: . *** * : : * ::*: *:*** ***:: :*:.: **::.:*.:: ", "identical_positions": 164, "similar_positions": 93, "identity": "46.07%" }, { "cls_id": "homologset.agr.SGD:S000005456", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63159-1", "uniprot_id": "COQ3_RAT", "id": "Q63159-1", "name": "Ubiquinone biosynthesis O-methyltransferase, mitochondrial", "aln": "MWRGGRLSSRGVRFLETLG-FACPSAVAEPPRVTSWTAFSGNQLTRNLQIKPWEFSGHRTMWLRSYRITFSCLTRLKTYRSSWKKLYSTSQT-VDSKEVKTFQALAHSWWDEQGKFAPLHSMNDLRVPFIRDNLLKTSTNHD--------------------------------PGKPLSGMKILDVGCGGGLLTEPLGRLG--ASVVGIDPVAENIKIAQHHKSFD-PVLDKRIQYRVCSLEETLNENAECFDAVVASEVVEHVNNLEMFIQCCYQVLKPG-GSLFITTVNKTQLSYVLGIVFSEQIAGIVPKGTHTWEKFVSPEKLESILEPNGLSVETVAGMVYNPFSGYWHWTENTSLNYAAHAVRARAQEHLEPAESA------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMS4-1", "uniprot_id": "COQ3_MOUSE", "id": "Q8BMS4-1", "name": "Ubiquinone biosynthesis O-methyltransferase, mitochondrial", "aln": "MWRGGRLGSRGVRLLETLG-FGCPSAVAQPPRLTSRSAYSGTQLTRNLQIKPWELGEHGTMCFRSYRMALSCLSRVKTYRTPWKRLYSTSQTTVDSREVKNFQALAHTWWDEYGKFAPLHSMNDLRVPFIRDNLLKTSASHH--------------------------------PGKPLSGMKILDVGCGGGLLTEPLGRLG--ASVVGIDPVAENIKIAQHHKSFD-PVLDKRIQYKVCSLEEAVDESAECFDAVVASEVVEHVSHLEMFIQCCYQVLKPG-GSLFITTVNKTQLSYALGIVFAEQIAGIVPKGTHTWEKFVSPEKLESILEPNGLSVETVAGLVYNPFSGYWHWSENTSLNYAAHAVRSRAQEHQEPAESALKGETGALHANTSGSPSVREEQRT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZJ6-1", "uniprot_id": "COQ3_HUMAN", "id": "Q9NZJ6-1", "name": "Ubiquinone biosynthesis O-methyltransferase, mitochondrial", "aln": "MWSGRKLGSSGGWFLRVLGPGGCNTKAARP--LISSAVYVKNQLSGTLQIKPGVFNEYRTIWFKSYRTIFSCLNRIKSFRYPWARLYSTSQTTVDSGEVKTFLALAHKWWDEQGVYAPLHSMNDLRVPFIRDNLLKTIPNHQ--------------------------------PGKPLLGMKILDVGCGGGLLTEPLGRLG--ASVIGIDPVDENIKTAQCHKSFD-PVLDKRIEYRVCSLEEIVEETAETFDAVVASEVVEHVIDLETFLQCCCQVLKPG-GSLFITTINKTQLSYALGIVFSEQIASIVPKGTHTWEKFVSPETLESILESNGLSVQTVVGMLYNPFSGYWHWSENTSLNYAAYAVKSRVQEHPASAEFVLKGETEELQANACTNPAVHEKLKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIF3-1", "uniprot_id": "Q9VIF3_DROME", "id": "Q9VIF3-1", "name": "Ubiquinone biosynthesis O-methyltransferase, mitochondrial", "aln": "------------------------------------------------------MMRNALLVSGKLRHLLSCSIGRNSTRSSST---AKSLDAGTQKEVRHHENHASEWWNQNGTMGALHALNEIRVPFIRDGIVSRGTVKPG----------------------------YVNTTKVLLGQNILEVGCGGGLLTEHLARLG--AQVAGIDLGEKLIEAAREHLKCSSPELASNVVYKIEPVDQHAKANCECYDAVIVSEVLEHVKDKVSLLEASVRSLKPG-GSIFITTLNKTIPSWFGGVLLSEYVLNLVPRGTHHWDKMISPLDVQRILDTS----KFISGFIFR--LGYSLFSRSSAVNCQTVLVNGSTYDFWSNTWRWINNNQMCYALQAVKQAQREYN---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P27680-1", "uniprot_id": "COQ3_YEAST", "id": "P27680-1", "name": "Ubiquinone biosynthesis O-methyltransferase, mitochondrial", "aln": "-----------------------------------------------------MLLRSRFLKVIHVRKQLSACS-----RFAIQTQTRCKSTDASEDEVKHFQELAPTWWDTDGSQRILHKMNLTRLDFVQRTVRNQVKIQNPEIFVPGFNYKEFLPEYVCDNIQREMQESIETNLDKRPEVSVLDVGCGGGILSESLARLKWVKNVQGIDLTRDCIMVAKEHAKKD-PMLEGKINYECKALEDVTGQ----FDIITCMEMLEHVDMPSEILRHCWSRLNPEKGILFLSTINRDLISWFTTIFMGENVLKIVPKGTHHLSKYINSKEILAWFNDNYSGQFRLLDLKGTMYLPYQGWVEHDCSDVGNYFMAIQRLN--------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * :*. * . . . **: . * **: * ** :* *: *:: : . : . .:*:******:*:* *.** .* *** . * *: * . . * * .: *. .::: :* : *::*** ::. . *:* * :*::*:*: *: :.:.* : :**:*** .* :.. : :: . : .: * : . . : : : ", "identical_positions": 56, "similar_positions": 75, "identity": "13.76%" }, { "cls_id": "homologset.agr.SGD:S000005457", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P32921-1", "uniprot_id": "SYWC_MOUSE", "id": "P32921-1", "name": "Tryptophan--tRNA ligase, cytoplasmic", "aln": "MADMPSGESCTSPLELFNSIATQGELVRSLKAGNAPKDEIDSAVKMLLSLKMSYKAAMGEEYKAGCPPGNPTAGRNCDSDATKASEDFVDPWTVR-----TSSAKGIDYDKLIVQFGSSKIDKELINRIERATGQRPHRFLRRGIFFSHRDMNQILDAYENKKPFYLYTGRGPSSEAMHLGHLVPFIFTKWLQDVFNVPLVIQMSDDEKYLWKD-LTLEQAYSYTVENAKDIIACGFDINKTFIFSDLEYMGQSPGFYRNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAVQAAPSFSNSFPKIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGHPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKSKVNKHAFSGGRDTVEEHRQFGGNCEVDVSFMYLTFFLEDDDRLEQIRKDYTSGAMLTGELKKTLIDVLQPLIAEHQARRKAVTEETVKEFMTPRQLSFHFQCFCFDT---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P7B0-1", "uniprot_id": "SYWC_RAT", "id": "Q6P7B0-1", "name": "Tryptophan--tRNA ligase, cytoplasmic", "aln": "MADMPSGESCTSPLELFNSIAAQGELVRSLKAGNAPKDEIESAVKMLLSLKMNYKTAMGEEYKAGCPPGNSTAGSNGDPDATKASEDFVDPWTVR-----TSSAKGIDYDKLIVQFGSSKIDKELINRIERATGQRPHRFLRRGIFFSHRDMNQILDAYENKKPFYLYTGRGPSSEAMHLGHLVPFIFTKWLQDVFDVPLVIQMSDDEKYLWKD-LTLEQAYSYTVENAKDIIACGFDVNKTFIFSDLEYMGQSPGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAVQAAPSFSNSFPKIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGHPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKSKVNKHAFSGGRDTVEEHRQFGGNCEVDVSFMYLTFFLEDDDSLEQIRKDYTSGAMLTGELKKTLIDVLQPLIAEHQARRKAVTEETVKEFMAPRQLSFHFQCFCFDT---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23381-1", "uniprot_id": "SYWC_HUMAN", "id": "P23381-1", "name": "Tryptophan--tRNA ligase, cytoplasmic", "aln": "---MPNSEP-ASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKADCPPGNPAPTSNHGPDATEAEEDFVDPWTVQ-----TSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKD-LTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PBS3-1", "uniprot_id": "SYWC_DANRE", "id": "Q6PBS3-1", "name": "Tryptophan--tRNA ligase, cytoplasmic", "aln": "---------MSSPLDLYECVTAQGETVRSIKAKKGSKEEVDAAVQVLLQMKLDYKRVTGQDYKAGCPPQDGVTPQDG--AAPQDGEDQVDPWSVS-----SSSAKGVDYEKLIVRFGSSKVDQELVDRISRLTGKTPHRFLRRGIFFSHRDMHQILDAFEQQKPFYLYTGRGPSSQAIHVGHLIPFIFTKWLQDVFDVPLVIQLTDDEKYLWKD-LTLEECRRFTVENARDIIACGFDVNKTFIFSDLEYMGASPAFYRNVVKVQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFGDRKDVQCLIPCAIDQDPYFRMTRDVAPRIGYLKPALLHSTFFPALQGAQTKMSASDANSTIFLTDTPKQIKNKVNKHAFSGGKDTIEEHRKLGGDPDVDVSFMYLTFFLEDDEQLEKIRQDYSSGAMLTGELKKSLIDTLQPIIAEHQEKRKHVTDDIVQQFMTPRKLHFSC----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0KI98-1", "uniprot_id": "Q0KI98_DROME", "id": "Q0KI98-1", "name": "Tryptophan--tRNA ligase, cytoplasmic", "aln": "-----------------------------------MADTKETVVEGVEALTLNGK--------PDAEPVETGTDAQAQEGATAPTEDVVDPWNVA-----SSNDAGVDYDKLIKRFGSSKIDEELIARFEKITGKPAHHFIRRGMFFSHRDLHTILTLREQGKPFYLYTGRGPSSGSLHVGHLVPFIMTKWLQETFDVPLVIQLTDDEKTLWKD-LKVEDAIKLGRENAKDIVAIGFDVNKTFIFNNLEFVGKCPAMYQNIIRIQKCVTFNQVKGIFGFGDSDIIGKIGFPAAQAAPAISSTFPFIFGNRK-VHCLIPCAIDQDPYFRMTRDVAPRLGFPKCALIHSTFFPALQGAKTKMSASDQNSAVYLTDTPKQIKNKINKYAFSGGRVSVEEHRKLGGVPEVDVSYQLLKFFLEDDAKLEEVRVAYSKGEMLTGEIKKLAVETLTPIVEQHQAARKLITDEVLDKYFELRPLKFGS----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12109-1", "uniprot_id": "SYWC_YEAST", "id": "Q12109-1", "name": "Tryptophan--tRNA ligase, cytoplasmic", "aln": "---------------------------------MSNDETVEKVTQQVSELK-----------------------------STDVKEQVVTPWDVEGGVDEQGRAQNIDYDKLIKQFGTKPVNEETLKRFKQVTGREPHHFLRKGLFFSERDFTKILDLYEQGKPFFLYTGRGPSSDSMHLGHMIPFVFTKWLQEVFDVPLVIELTDDEKFLFKHKLTINDVKNFARENAKDIIAVGFDPKNTFIFSDLQYMGG--AFYETVVRVSRQITGSTAKAVFGFNDSDCIGKFHFASIQIATAFPSSFPNVLGLPDKTPCLIPCAIDQDPYFRVCRDVADKLKYSKPALLHSRFFPALQGSTTKMSASDDTTAIFMTDTPKQIQKKINKYAFSGGQVSADLHRELGGNPDVDVAYQYLSFFKDDDVFLKECYDKYKSGELLSGEMKKLCIETLQEFVKAFQERRAQVDEETLDKFMVPHKLVWGEKERLVAPKPKTKQEKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ..: : :. :. *: * ** * . .:**:*** :**:. :::* : *:.: **: .*:*:*:*:***.**: :* *: ***:********* ::*:**::**::*****:.*:*****:::**** *:*. *.::: ***:**:* *** ::****.:*:::* .:*..::::.: :* . .*.:*** *** ***: *.: * *.::..:** :: **************: **** :: . * **:** *******: ******* .:::::***.***:.*:**:*****: : : **::** :***:: *.** :** *:: *..* :*:**:** ::.* :: .* * : :: :.::: : * : ", "identical_positions": 169, "similar_positions": 140, "identity": "34.07%" }, { "cls_id": "homologset.agr.SGD:S000005460", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55173-1", "uniprot_id": "PDPK1_RAT", "id": "O55173-1", "name": "3-phosphoinositide-dependent protein kinase 1", "aln": "------------------------------------------------------------MARTTSQLYDAVPIQSSVVLCSCPSPSMVRSQTEPSSSPGIPS-------------------------------------GVSRQGSTMDGTTAEARPSTN---------------------PLQQHP-----------------------AQLPPQPRKKR-----------------------PEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLD-HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPDS---------KQARAN------------------------------------------------------SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEG------------------------------------------------------------------------------------------------------------------------------------------------------------------------YGPLKAHPFFESITWENLHQQTPPKLTAYLPAMSEDD--EDCYGNYDNLLSQFGCMQVSSSSSSHSLSAVDASLPQRSGSNIEQYIHDLDTNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDK-----------------------------------------------------------------------------------------------------------------------------------RKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQQYQSSPDAAVQ---------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2A0-1", "uniprot_id": "PDPK1_MOUSE", "id": "Q9Z2A0-1", "name": "3-phosphoinositide-dependent protein kinase 1", "aln": "------------------------------------------------------------MARTTSQLYDAVPIQSSVVLCSCPSPSMVRSQTEPGSSPGIPS-------------------------------------GVSRQGSTMDGTTAEARPSTN---------------------PLQQHP-----------------------AQLPPQPRKKR-----------------------PEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLD-HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPES---------KQARAN------------------------------------------------------SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYHFPEKFFPKARDLVEKLLVLDATKRLGCEEMEG------------------------------------------------------------------------------------------------------------------------------------------------------------------------YGPLKAHPFFETITWENLHQQTPPKLTAYLPAMSEDD--EDCYGNYDNLLSQFGFMQVSSSSSSHSLSTVETSLPQRSGSNIEQYIHDLDTNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDK-----------------------------------------------------------------------------------------------------------------------------------RKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQQYQSNPDAAVQ---------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15530-1", "uniprot_id": "PDPK1_HUMAN", "id": "O15530-1", "name": "3-phosphoinositide-dependent protein kinase 1", "aln": "------------------------------------------------------------MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIP--------------------------------------GGSRQGPAMDGTAAEPRPGAG---------------------SLQH-------------------------AQPPPQPRKKR-----------------------PEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLD-HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPES---------KQARAN------------------------------------------------------SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEG------------------------------------------------------------------------------------------------------------------------------------------------------------------------YGPLKAHPFFESVTWENLHQQTPPKLTAYLPAMSEDD--EDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDK-----------------------------------------------------------------------------------------------------------------------------------RKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRYQSHPDAAVQ---------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6A1A2-1", "uniprot_id": "PDPK2_HUMAN", "id": "Q6A1A2-1", "name": "Putative 3-phosphoinositide-dependent protein kinase 2", "aln": "---------------------------------------------------------------------------------------MVRTQTESSTPPGIP--------------------------------------GGSRQGPAMDGTAAEPRPGAG---------------------SLQH-------------------------AQPPPQPRKKR-----------------------PEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLD-HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMYIQITDFGTAKVLSPES---------KQARAN------------------------------------------------------SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEG------------------------------------------------------------------------------------------------------------------------------------------------------------------------YGPLKAHPFFESVTWENLHQQTPPKLTAYLPAMSEDD--EDCYGNVS----------------------------------------------------------------------WPGWRAR--QVALGPP-------------------------------------------------------------------------------------------------------------------------------------CTGLHARAP-------------DPR-------VICSRKGR----------VSVPLR------------------QACWWL--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W0V1-4", "uniprot_id": "PDPK1_DROME", "id": "Q9W0V1-4", "name": "3-phosphoinositide-dependent protein kinase 1", "aln": "---MKCKSWSNKINNYVVRKIKSIKINGTQQQLQLPGSGASGIAAAAVITVASDCGENCSSNGTEHQQHFNIATTTATSATEATMPAMAKEKASATVSLGESNFRDINLKDLAVVVEAASRLHHQQNVCGCGAVSSTENNNNSRYGSSKYLTNGHTSPLAAAVASNSSSVATTPHCRMLHNCSLQQYQNDIRQQTEILDMLRQQHQQGYQSQQQQQQPQQQQEQQQQQEQSQQQQQLQNPAPRRSPNDFIFGRYIGEGSYSIVYLAVDIHSRREYAIKVCEKRLILRERKQDYIKREREVMHQMTNVPGFVNLSCTFQDQRSLYFVMTYARKGDMLPYINRVGSFDVACTRHYAAELLLACEHMHRRNVVHRDLKPENILLDEDMHTLIADFGSAKVMTAHERALATEHCSEQRRSNSDEDDEDSDRLENEDEDFYDRDSEELDDGDDEQQQEEMDSPRHRQRRYNRHRKASFVGTAQYVSPEVLQNGPITPAADLWALGCIVYQMIAGLPPFRGSNDYVIFKEILDCAVDFPQGFDKDAEDLVRKLLRVDPRDRLGAQDEFGY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------YESIRAHPFFAGIDWQTLRQQTPPPIYPYLPGVSQDEDFRSSYTVPGDLEPGLDERQISRLLSAELGVGSSVAMPVKRST---------AKNSFDLN-----DAEKLQRLEQQKTDKWHVFADGEVILKKGFVNK-----------------------------------------------------------------------------------------------------------------------------------RKGLFARKRMLLLTTGPRLIYIDPVQMIKKGEIPWSPDLRAEYKNFKIFFVHTPNRTYYLDDPEGYAIHWSEAIENMRKLAYGDPSSTSAVS------CSSGSSNSLAVISNSSAASSSNSPTVKRSSPVNAPQASTASDNRTLGSTRTGTSPSKKTASK------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12236-1", "uniprot_id": "PKH2_YEAST", "id": "Q12236-1", "name": "Serine/threonine-protein kinase PKH2", "aln": "MYFDKDNSMSPRPLLPSDEQKLNINLLTKKEKFSHLDPHYDAKATPQRSTSNRNVGDLLLEKRTAKPMIQKALTNTDNFIEMYHNQQRKNLDDDTIKEVMINDENG----------------------------KTVASTNDGRYDNDYDNNDINDQKTLDNIAGSPHMEKNRNKVKIEHDSSSQKPIAK-------------------ESSKAQKNIIKKG-----------------------IKDFKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSK------------------------------------------------------SFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQYAFTPGFPLIIRDLVKKILVKNLDRRLTISQIKEHHFFKDLNFKDGSVWSKTPPEIKPYKINAKSMQAMPSGSDRKLVKKSVNTLGKSHLVTQRSASSPSVEETTHSTLYNNNTHASTESEISIKKRPTDERTAQILENARKGINNRKNQPGKRTPSGAASAALAASAALTKKTMQSYPTSSSKSSRSSSPATTSRPGTYKRTSSTESKPFAKSPPLSASVLSSKVPMPPYTPPMSPPMTPYDTYQMTPPYTTKQQDYSDTAIAAPKPCISKQNVKNSTDSPLMNKQDIQWSFYLKNINEHVLRTEKLDFVTTNYDILEKKMLKLNGSLLDPQLFGKPRHTFLSQVARSGGEVTGFRNDPTMTAYSKTEDTYYSKNIIDLQLLEDDYRIEGGDLSELLTNRSGEGYKCNQNSSPMKDDDKSESNNKGSSVFSGKIKKLFHPTSAAETLSSSDEKTKYYKRTIVMTSFGRFLVFAKRRQPNPVTNLKYELEYDINLRQQGTKIKELIIPLEMGTNHIVVIQTPYKSFLLSTDKKTTSKLFTVLKKILNSNTNKIEKELLQRNQKVIERRTSSSGRAIPKDLPTSKSPSPKPRTHSQSPSISKHNSFSESINSAKSNRSSRIFETFINAKEQNSKKHAAPVPLTSKLVNGLPKRQVTVGLGLNTGTNFKNSSAKSKRS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .. . .* . . . . *: : : :: :** ** :*:*::* * ** .: : :.** *: :*. ::::.* *:. *: .: :: * .*.* ****: .*** : ** :*::* :.: **:* :*:*.*:*::: * :::* ..::***:*******: :* ::***:**::.. . . *:: ******:*****:* : .*:**:***::*::** ***:. *:*: *::::. *. * .***.*:* : ** .: . .::** . .: : .* * :* . * : :.*: . : .* : : ", "identical_positions": 103, "similar_positions": 126, "identity": "8.55%" }, { "cls_id": "homologset.agr.SGD:S000005461", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6TCH7-1", "uniprot_id": "PAQR3_HUMAN", "id": "Q6TCH7-1", "name": "Progestin and adipoQ receptor family member 3", "aln": "----------------------------------------------MHQKLLKSAHYIELGSYQYWPVLVPRGIRLYTYEQIPGSLKDNPYITDGYRAYLPS-RLCIKSLFILSNETVNIWSHLLGFFLFFTLGIYDMTSVLPSASASREDFVICSICLFCFQVCMLCSVGYHLFSCHRSEKTCRRWMALDYAGISIGILGCYVSGVFYAFYCNNYWRQVYLITVLAMILAVFFAQIHPNYLTQQWQRLRSIIFCSVSGYGVIPTLHWVWLNGGIGAPIVQDFAPRVIVMYMIALLAFLFYISKVPERYFPGQLNYLGSSHQIWHILAVVMLYWWHQSTVYVMQYRHSKPCPDYVSHL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6TCG8-1", "uniprot_id": "PAQR3_MOUSE", "id": "Q6TCG8-1", "name": "Progestin and adipoQ receptor family member 3", "aln": "----------------------------------------------MHQKLLKSAHYIELGSYQYWPVLVPRGIRLYTYEQIPVSLKDNPYITDGYRAYLPS-RLCIKSLFILSNETVNIWSHLLGFFLFFTLGIYDMTSVLPSASASREDFVICSICLFCFQVCMLCSVGYHLFSCHRSEKTCRRWMALDYAGISIGILGCYVSGVFYAFYCNNYWRQVYLITVLAMILAVFFAQIHPSYLTQQWQRLRPIIFCSVSGYGVIPTLHWVWLNGGVSAPIVQDFAPRVIVMYVIALLAFLFYISKVPERYFPGQLNYLGSSHQIWHVLAVVMLYWWHQSTVYVMQYRHSKPCPDYVSHL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58JI11-1", "uniprot_id": "A0AC58JI11_DANRE", "id": "A0AC58JI11-1", "name": "", "aln": "-----------MPELGEKLSATLRMPGVQRRASGSLGVRLGDVIIMPSAKVLKNTQYIELGSYQYWPVLVPRGIRLYTYEQVPAFLRENPYITDGYRAYLTS-RLCIKSIFILSNETVNIWSHLLGFFLFFTLGVYDLLAVLPMLGASREDYVIYSIGLFCFQVCMLCSVGFHLFCCHRSEKTSRRWMALDYAGISIGIIGCYVPGVFYAFYCNNYWRQVYLVTVLAMMLAVFFAQIHPHYLSKKWQKLRSLLFCAVAGYGLIPTFHWIWISGGFGSQIVQEFLPKVLIMYLLAVAAIVFYMSKVPERYFPGQLNYLGSSHQVWHILVVLMFYWWHQAALFITSYRHSHPCPDHPLHS----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFG7-1", "uniprot_id": "Q9VFG7_DROME", "id": "Q9VFG7-1", "name": "Progestin and adipoQ receptor family member 3", "aln": "MSPRPREILEEPELSLDSSSCYLRKSGQDCDDSCLLDGQLVADSVDAAHQFPSNEEPNILGHGPNYDDKLSKFKWLCNFDDAPSHLKFNPYIRRGYRTFLPSTKMCLQSIFWWTNETINIWSHLAGCILFIGLTIFDLQFLR--LHASLSDQVLVVCLLVCFCLCMLMSAIYHIFSCK-SEEHYELFLSVDFLGISLSLVAIYISGMYYAFWCHTFLRTLYSTIALGMFALAIAVQIPRLNVSMNGKVAVLLLWS---AYGIIPLGHWAVAMGGLENELVRLMVPRIVLMYLLCLVAFVFYAAKIPERWFTGKVDFVGHSHNWWHLIIVAAFYHWHNTGLVYAEYRLNNGCTAPVLS-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99393-1", "uniprot_id": "IZH4_YEAST", "id": "Q99393-1", "name": "ADIPOR-like receptor IZH4", "aln": "----------------------------------MVSLTTIEQSPVKCETTTEKESNDTRGTDSNENAETKETKKGFPFHDLAKLQKQYKNKSSRNESLVAL---------------IYLLGSMLSFCLLIFFTDFYLIPLFP-TTTTMTDYIVFNFYLLNVFVFCMVHFIYHFVKNISLQQHLEHWQKFSYLSNINLLISSQITILYYLFYDYVFFFKIFTLLMNFIGLVAYFFILTDKLISSKRFNKTVFFISVSVVCCSLPLLTAIITFDGLENLKERIKVNAITWELVALVAASIIYVTRFPESLFRRNKKEEGWNHSEYLFHLLISGTAFYHFFILIQSYILMHSSLNQPELINFKS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. * . :.: . : .: :. : : . : . *:: : : : : :: * :: *. . : : :*:. :: . : ..: . ::. :. ::* *: : :: : . : :: : :: . :* .*. : : : : * ::* ::.** * : . * .*. : . : ::: : .* : . ", "identical_positions": 17, "similar_positions": 88, "identity": "4.7%" }, { "cls_id": "homologset.agr.SGD:S000005462", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M212-1", "uniprot_id": "A0ABK0M212_RAT", "id": "A0ABK0M212-1", "name": "2'-phosphotransferase", "aln": "MDWVLVMNAPGGRRQE-----GRRTHRPREQDRNVQLSKALSYALRHGALKLGLPMRADGFVPLQALLQLPQFHS--FSIEDVQLVVDTNEKQRFTLQPGEPSTGPLIRANQGHSLQVPELELMPLETP---QALPSTLVHGTFWKHWPSILLN-GLSRQGRTHIHLASGLPGDSGVISGIRPNCEVAVFINGALALTDG-IPFFCSVNGVILTPGNADGFLLPKYFKEALQLRPTRKPLSLTGDKETESQSGPKHSSRGGRRKIQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K3A2-1", "uniprot_id": "TRPT1_MOUSE", "id": "Q8K3A2-1", "name": "tRNA 2'-phosphotransferase 1", "aln": "------MNAPGGRRKE-----GRRTHRPREQDRNVQLSKALSYALRHGALKLGLPMRADGFVPLQALLQLPQFHS--FSIEDVQLVVNTNEKQRFTLQPGEPSTGLLIRANQGHSLQVPELELTPLETP---QALPLTLVHGTFWKHWPSILLK-GLSRQGRTHIHLASGLPGDPGVISGIRPNCEVAVFIDGPLALTDG-IPFFCSANGVILTPGNAEGFLLPKYFKEALQLRPTRKPLSLAGDKETETQSGPKLSSRGGRRKIQQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86TN4-1", "uniprot_id": "TRPT1_HUMAN", "id": "Q86TN4-1", "name": "tRNA 2'-phosphotransferase 1", "aln": "------MNFSGGGRQEAAGSRGRRAPRPREQDRDVQLSKALSYALRHGALKLGLPMGADGFVPLGTLLQLPQFRG--FSAEDVQRVVDTNRKQRFALQLGDPSTGLLIRANQGHSLQVPKLELMPLETP---QALPPMLVHGTFWKHWPSILLK-GLSCQGRTHIHLAPGLPGDPGIISGMRSHCEIAVFIDGPLALADG-IPFFRSANGVILTPGNTDGFLLPKYFKEALQLRPTRKPLSLAGDEETECQSSPKHSSRE-RRRIQQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5EAR5-1", "uniprot_id": "TRPT1_DANRE", "id": "Q5EAR5-1", "name": "tRNA 2'-phosphotransferase 1", "aln": "------MDCETRGRGR-----RGRGNR-NEESRDVRLSKSLSYVLRHGASKMGLQMNSDGFVFVEELLAHQQFRS--FSVDDVERVVASNDKQRFKLCKHPEDDRLQIRANQGHSVQVTDLELREISQDD--QDYPREAVHGSYMKHWPSIRSQ-GLSRMNRTHIHLAPGLPGEGRVISGMRQSCDLAVYIDVTKAMSDG-IKFFWSENGVLLTPGDAAGILAPCYFSRAQRLKP------LPCDIELH------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86BH3-1", "uniprot_id": "Q86BH3_DROME", "id": "Q86BH3-1", "name": "2'-phosphotransferase", "aln": "------MAS--------------------NQQINTQLSKKLSWLLRHGAKTEGITIRADGFVSVPDLQKHPRYLC--FTLEKLKEIAAADAKQRYTLRWNPELGVHEIRANQGHSLAVLEGEAGGLENITH-VSQVPLAVHGTYYRHWGAIRSQ-GLSRMNRNHVHFACSDETNS-TLSGFRSDCQILIYLNVEKVLADG-IPIYRSSNNVLLCPG-IEGFIHSSYFQRVVDKKTG-----QPLQIDHCY-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12272-1", "uniprot_id": "TPT1_YEAST", "id": "Q12272-1", "name": "tRNA 2'-phosphotransferase", "aln": "-----------------------MRQVLQKDKRDVQLSKALSYLLRHTAVKEKLTIDSNGYTPLKELLSHNRLKTHKCTVDDIHRIVKENDKQRFHIKTLG-ADEEWICATQGHSIKSIQPSDEVLVPITEASQLPQELIHGTNLQSVIKIIESGAISPMSRNHVHLSPGMLHAKGVISGMRSSSNVYIFIDCHSPLFFQTLKMFRSLNNVYLSSSIPVELIQKVVVKGNLKDEEKLDTLRRILHERNIPLEKI-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. :.:*** **: *** * . : : ::*:. : * : : :.:. :. : ***: : * *.****: . . : :**: : * . .:* .*.*:*:: . :**:* .:: :::: : : :: * *.* * .. :: .. . . ", "identical_positions": 34, "similar_positions": 65, "identity": "12.73%" }, { "cls_id": "homologset.agr.SGD:S000005463", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q921A2-1", "uniprot_id": "MYCT_RAT", "id": "Q921A2-1", "name": "Proton myo-inositol cotransporter", "aln": "MSRKASEDVEYTLRSLSSLMGERRRRQPEPGAP-------GGERSLLAA-ESAASLQGA--------ELERAARRQFQRDE-----------------------TPAFVYAAAAFSALGGFLFGYDTGVVSGAMLLLRRQMR---LGAMWQELLVSGAVG--AAAVAALAGGALNGALGRRSAILLASALCTVGSAVLAAAANKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAIPAVIQFLGFLFLPESPRWLIQKGQTQKARRILSQMRG----NQTIDEEYDSIRNSIE--EEEKEASAAGPIICRMLSYPPTRRALAVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASITAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALTILALGFLLSAQVSPRVTFRPTAPSGQNATCTEYSYCNECMLDPDCGFCYKINSSAVIDSSCVPVNKASTNEAAWGRCENETKFKAEDVHWAYSFCPTPYSWTALVGLVLYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFVYGCLPETKGKKLEEIESLFDHRLCTCGT----------------ADSDEGRYIEYIRVKGSN------------YHLSDNDASDVE-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UHK1-1", "uniprot_id": "MYCT_MOUSE", "id": "Q3UHK1-1", "name": "Proton myo-inositol cotransporter", "aln": "MSRKASEDVEYTLRSLSSLMGERRRRQPEPGAP-------GGERSLLAA-ESAASLQGA--------ELERAARRQFQRDE-----------------------TPAFVYAAAAFSALGGFLFGYDTGVVSGAMLLLRRQMR---LGAMWQELLVSGAVG--AAAVAALAGGALNGALGRRSAILLASALCTVGSAVLAAAANKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAIPAVIQFLGFLFLPESPRWLIQKGQTQKARRILSQMRG----NQTIDEEYDSIRNSIE--EEEKEATAAGPIICRMLSYPPTRRALVVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASITAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFLLSAQVSPRVTFRPTTPSDQNTTCTGYSYCNECMLDPDCGFCYKINGSAVIDSSCVPVNKASTTEAAWGRCDNETKFKAEGAHWAYSFCPTPYSWTALVGLVLYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFVYGCLPETKGKKLEEIESLFDHRLCSCGA----------------ADSDEGRYIEYIRVKGSN------------YHLSDNDASDVE-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96QE2-1", "uniprot_id": "MYCT_HUMAN", "id": "Q96QE2-1", "name": "Proton myo-inositol cotransporter", "aln": "MSRKASENVEYTLRSLSSLMGERRRKQPEPDAAS-----AAGECSLLAAAESSTSLQSAGAGGGGVGDLERAARRQFQQDE-----------------------TPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLS---LDALWQELLVSSTVG--AAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMRG----NQTIDEEYDSIKNNIE--EEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSPRITFKPIAPSGQNATCTRYSYCNECMLDPDCGFCYKMNKSTVIDSSCVPVNKASTNEAAWGRCENETKFKTEDIFWAYNFCPTPYSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNRLCTCGT----------------SDSDEGRYIEYIRVKGSN------------YHLSDNDASDVE-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BA61-1", "uniprot_id": "A0A8M2BA61_DANRE", "id": "A0A8M2BA61-1", "name": "Proton myo-inositol cotransporter", "aln": "-------------------MEDQR---------------------AYARVEDESTLIKT-----------ASKRDHELQPG-----------------------PPCFVYTLAFFSALGGFLFGYDTGVVSGAMLLLKREKK---LSSVWQELLVSITVG--AAAVSALAGGFLNGRFGRRVCILLASFIFCAGGIILSVARNKEALLCGRLTVGLGLGIASMTVPVYIAEVSPPDLRGQLVTVNTLFITGGQFIASVVDGAFSYLPHDGWRFMLGLSVVPAALQFLGFLFLPESPRWLLQKGFTQNALLVLRQIRG----DVDVEEEFESIRCSIQ--EEQRDV-AGGPVLWRMLASPPARRALIVGCGLQMFQQLAGINTVMYYSATILQMSGVQDDQMAIWLAAGTAFTNFLFTLVGVWLVERVGRRRLTMASLLGTAVSLMVLAAGFLLSAQASPPVTFHPSNPSIHNSTCGNYGFCESCMLDPDCGFCYGLNATAVVQSSCVPVDPANTETAALGRCFNGTQ-KASSVFWAYNYCPTPYSWVVLLGLILYLAFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGVNWICNVLVSLTFLHVAQYLTYYGAFFLYAALALLGFVFVSGCLPETKGLRLEEIESLFSRRLCSCGAHTDQYMRRLEFGALHYATSEPEGRISYISVSTSQKKTKSLILISVLFHSRKNIEHNIFVLPLHFEFTEEVD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P30606-1", "uniprot_id": "ITR2_YEAST", "id": "P30606-1", "name": "Myo-inositol transporter 2", "aln": "MKNSTAASSRWTKSRLSHFFPSYTNSSGMGAASTDQSSTQGEELHHRKHCEEDNDGQKPKKSPVSTSTMQIKSRQDEDEDDGRIVIKPVNDEDDTSVIITFNQSISPFIITLTFVASISGFMFGYDTGYISSALISINRDLDNKVLTYGEKELITAATSL--GALITSVGAGTAADVFGRRPCLMFSNLMFLIGAILQITAHKFWQMAAGRLIMGFGVGIGSLISPLFISEIAPKMIRGRLTVINSLWLTGGQLIAYGCGAGLNHVKN-GWRILVGLSLIPTVLQFSFFCFLPDTPRYYVMKGDLKRAKMVLKRSYVNTE-DEIIDQKVEELSSLNQSIPGKNPITKFWNMVKELHTVPSNFRALIIGCGLQAIQQFTGWNSLMYFSGTIFETVGFKNSSAVSIIVSG---TNFVFTLIAFFCIDKIGRRYILLIGLPGMTVALVICAIAFHFLG---------------------------------------------------IKFNGADAVVASDG--------------------FSSWGIVIIVFIIVYAAFYALGIGTVPWQQ-SELFPQNVRGVGTSYATATNWAGSLVIASTFLTMLQNITPTGTFSFFAGVACLSTIFCYFCYPELSGLELEEVQTILKDGFNIKAS-----------------KALAKKRKQQVAEGAAH------------HKLKFEPTQEIVES-----------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VQP1-1", "uniprot_id": "Q9VQP1_DROME", "id": "Q9VQP1-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------MTFKLRLASVFANPN---------CLLGRR------------------------------IRHQFLVTLLLNIATFSHGLGVGWMSPVMRDLQTDESPLDFPVLVSQVSWIGSLVGIGSVMGNLIAGLLMDRIGRKMVLFFIAIPYTTFWCLIYFVQSVEFLYIGRLMAGITGGACYVVLPTFISEIADTNVRGRLGSIILLSVNTGVLAGYIVSTRVDYFTSPPFIIGL------PVCYFICNFLIPETPHHLVRKGKFEAAKRSFMFYKNIRKNDIKAEDEFEEMKYLLI----KEQTEKAKSFDYRDFITRPAFKAYASAAVLLISNQFSASFCVTTYLADVFAASHTTLNLGMCTIIIG--VLQIVGNYVTTLLCDKYGRRILMLTSTLGASVCLTAFGTFTFFAEAAD----------------------------------------------------------------------------------LSSVDWLPLVILSCFVFLCNIGLVGCLFVVLVELFPAKIRSVSVSTFVVILSSTVFLTLKIFPICMAVWGTSVTMWSCSGITFFSFLYFCFFLEETNGKSLLAA------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * . : . :. * .* ..* :* .: :. : : .:: : .: : : .* . :**: ::: : . . : *** *: * : * :*:*:: :**:* : * :. * : . . ..:. : : .. * ::*::*: : ** : * : : ::: :.: :. . . . :* .. * :*::. : : . :: . : ::: . : :: *** : : . * :*.* . : :. . :: : : : *: : *::* *... : .: * :: :..: .. :: * .* * ", "identical_positions": 44, "similar_positions": 135, "identity": "6.04%" }, { "cls_id": "homologset.agr.SGD:S000005465", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80XH4-1", "uniprot_id": "WSCD1_MOUSE", "id": "Q80XH4-1", "name": "Sialate:O-sulfotransferase 1", "aln": "MAKPFFRLQKFLRRTQFLLLFLTAAYLMTGSLLLLQRARVALPQALRAPGSLQA-LPVATVALGVGLLDGRSLRDPHSSPDLLLDVDTLR-SPLARLPPGIRWPRRNRSSLRRRWLHHLTSDPQGPPTLSPEASGPANHNRGNYLGCFSEEGQERTLKGAVFYDLRKMTVSHCQDACAERSYVYAGLEAGAECYCGNRLPATRVSLKECNQECKGEKGSMCGAVRRLSVYSVGLQQPGSKKRRTATYRGCFPLPENVTHTFSSSMTQANMTVETCSGFCSQKEFP-LAILRGWDCYCAYPTPQFSLRDAVDGALCSQAPETQGLPGYCEVYQTPVQDTRCTDRKFLPDKSKVFVALSSFPGAGNTWARHLIEHATGFYTGSYYFDGTLYNKGFKGEKDHWRSRRTICVKTHESGRREIEMFDSAILLIRNPYRSLVAEFNRKCAGHLGYAPDRNWKSKEWPEFVNSYASWWSSHVLDWLKYGKRLLVVHYEELRHSLVPTLREMVAFLNVSVSEERLLCVENNKEGSFRRRGRRPHDQEPFTPEMKDLINGYIRTVDQALRDHNWAGLPREYVPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q505J3-1", "uniprot_id": "WSCD1_RAT", "id": "Q505J3-1", "name": "Sialate:O-sulfotransferase 1", "aln": "MAKPFFRLQKFLRRTQFLLLFLTAAYLMTGSLLLLQRARVALPQALRAPGSLQA-LPVATVALGVGLLDSRSLHDPHSSPDLLLDVDTLR-SPLARVPPGIRWPRRNRSSLRRRWLHHLTSDPQGPPTLGPEASGPASHNQGNYLGCFSEEGQERTLKGAVFYDLRKMTVSHCQEACAERSYVYAGLEAGAECYCGNRLPATRVSLKECNQECKGEKGSMCGALHRLSVYSVGLQQSGAKKRWTATYRGCFPLPENITRTFSSSMTQANVTVETCSGFCSQKEFP-LAILRGWACYCAYPTPQFSLRDAVDGALCSQGTEAQGLPGYCEVYQTPVQDTRCTDRKFLPNKSKVFVALSSFPGAGNTWARHLIEHATGFYTGSYYFDGTLYNKGFKGEKDHWRSRRTICVKTHESGRREIEMFDSAILLIRNPYRSLVAEFNRKCAGHLGYAPDRNWKSKEWPDFVNSYASWWSSHVLDWLKYGKRLLVVHYEELRHSLVPTLREMVAFLNVSVSEERLLCVENNKEGSFRRRGRHPHDQEPFTPEMKDLINGYIRTVDQALRDHNWAGLPREYVPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12215-1", "uniprot_id": "WSC3_YEAST", "id": "Q12215-1", "name": "Cell wall integrity and stress response component 3", "aln": "MERVWFAKLTNKGTIKIGYISFILLSLLCQSLIGLVNADFNYEGCYSAADIQSAGLSLKNSYIYQSVSYCQNQCPESAVVALFNGSDCYCGNSVSFLTSLTKSTDSNCGTKCSGWPYQMCGGSSYMNVYVNAETFVSSVESSSSKEGSSTSYMPSTTSSLSSAQISSTTRRTSTDMKSSEMIATTVSTTSTTSSSTSSTTSSTTSSTTSSTTSSTTSSSTSSTTSSTTSSTTSSTTSSTTSSTTSSTTSSTTSSTTSIFSVTSSSSSITLSSSEHTTVDSRTSSPSSTLVPVSSSSSTLSTPKVTSMTPSTSSTIPIVTSVELVT--SVVTKAIVSTSDQHQETIFVTRTSVVERSSEVATATAAASNNRSNSTSKQRLSGGAIAGIVIGVVFG-----VIFIILILLFLIWRRRKSHDQLDLEETKHYQPYS-----FGDEDANPIGPPPSSGTTNWMRHSRGNTAGSIGTSNMYGFSMSNG---ANYSSPSSNTSGSIINNLAGLQDATVQKQNLPSTVFEEANTLN----SANERFSANSLPDMMMSGPLQVVNPDNPDNPELSSTVSHNRA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : :* . :: : : *: **: * .* . . *.. .* *.: . : .: :. : *: . * ..:: :.. : . * .: * ::: .... . : :. : .. * . * .. :: . * . : :.. . : :.: . . . .:: .* . .. .. ..* ..: : :.. ..:.. *:: .. . . . :.:** :. .:: . : . *:.. * ::: . .: .**:.: . .: . ...: :. . * :: *. : :..:: ::.*. *... * : :.: : :: .. : * : . * * : *:. : :* :** *. : *. :* .*. . .. . *: .* :*:: .: . . : . :: . :.::..: :.:*.::.* .. :: .::. .::: . .. . ::.* ::.*: *: . . .: ", "identical_positions": 50, "similar_positions": 235, "identity": "8.7%" }, { "cls_id": "homologset.agr.SGD:S000005467", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZE59-1", "uniprot_id": "D3ZE59_RAT", "id": "D3ZE59-1", "name": "", "aln": "-------MQRALPGARQHLGAILASASVVVKALCAVVLFLYLLSFAVDTG-CLAVT---------PGYLFPPN-FWIWT--LATHGLMEQHVWDVAISLATVVVAGRLLEPLWG-ALELLIFFSVVNVSVGLLGAFAYLLTYMASFNLVYLFTIRIHGALGFLGGVLVALKQTMGDCVVLRVPQVRVS-------VVPMLLLALLLLLRLATLLQSPALASYGFGLLSSWVYLRFYQRHS-------------RGR----GDMADHFAFATFFPEILQPVVGLLANLVHGLLVKVKICQK--TVKRYDVGAPSSITISLPGTDPQDAE-RRRQLALKALNERLKRVEDQ--------------------------------------------------------------------------SAWPSMDDDEEEAGAKTDSPLPSEQASTPPGKGTAP------------ESTLITFEAAPLL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUH1-1", "uniprot_id": "TM115_MOUSE", "id": "Q9WUH1-1", "name": "Transmembrane protein 115", "aln": "-------MQRALPGARQHLGAILASASVVVKALCAVVLFLYLLSFAVDTG-CLAVT---------PGYLFPPN-FWIWT--LATHGLMEQHVWDVAISLATVVVAGRLLEPLWG-ALELLIFFSVVNVSVGLLGALAYLLTYMASFNLVYLFTIRIHGALGFLGGVLVALKQTMGDCVVLRVPQVRVS-------VVPMLLLALLLLLRLATLLQSPALASYGFGLLSSWVYLRFYQRHS-------------RGR----GDMADHFAFATFFPEILQPVVGLLANLVHGLLVKVKICQK--TVKRYDVGAPSSITISLPGTDPQDAE-RRRQLALKALNERLKRVEDQ--------------------------------------------------------------------------SAWPSMDDDEEEAGAKTDSPLPLEEASTPPGKVTVP------------ESSLITLETAPLL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12893-1", "uniprot_id": "TM115_HUMAN", "id": "Q12893-1", "name": "Transmembrane protein 115", "aln": "-------MQRALPGARQHLGAILASASVVVKALCAAVLFLYLLSFAVDTG-CLAVT---------PGYLFPPN-FWIWT--LATHGLMEQHVWDVAISLTTVVVAGRLLEPLWG-ALELLIFFSVVNVSVGLLGAFAYLLTYMASFNLVYLFTVRIHGALGFLGGVLVALKQTMGDCVVLRVPQVRVS-------VMPMLLLALLLLLRLATLLQSPALASYGFGLLSSWVYLRFYQRHS-------------RGR----GDMADHFAFATFFPEILQPVVGLLANLVHSLLVKVKICQK--TVKRYDVGAPSSITISLPGTDPQDAE-RRRQLALKALNERLKRVEDQ--------------------------------------------------------------------------SIWPSMDDDEEESGAKVDSPLPSDKAPTPPGKGAAP------------ESSLITFEAAPPTL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VMD2-1", "uniprot_id": "Q9VMD2_DROME", "id": "Q9VMD2-1", "name": "Transmembrane protein 115", "aln": "---MSAQLARNWPYIWQQLNALLHNTSPVITLICVVTTFGYLLSFSETAILLLSVT---------PGYILPNGKFWIWT--AFTFCFIELHWWEVAVDVVTVGLCGKMLEPLWG-QLEMFKFFALSNFGVSLLTTVYYLFYYMVTKNPTILFEVHIHGLAGYVAGICVAVRQIMPDHLIFKTRYGRLTNR-----NVPLTVLIMAIILWAIGLLDGTYPAMFASGSLVSWIYLRFYQHHP-------------NGR----GDSSESFTFVSFFPNVSQPFISVLVNPIYNCCLRAGVVKTPTPLRTISTASLTSVSVQMPGVDPHDIE-RRRQIALKALSERLKATDSSRHAQLPKSFPQQQQLQHHHHQHAPHQQQKHHSHGTGHSHSHGAGHSHSHGAGHSHGPGPAQMPQPDFLKSTGSASQLPITTSRAEPRMISTMSPIAIPMPAPPPKEGNVPGQGAESSSSGGVEATLINLDDVPTTSSMA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12239-1", "uniprot_id": "TM115_YEAST", "id": "Q12239-1", "name": "Transmembrane protein 115 homolog", "aln": "MQYSSRFLELNIPDSFLNINKIPDATKFITVTYICLTATLFCIRRSLYNKLVLEDPNLDYNLITSPLLQMVPSQIWRYPTSLVLSNFIDTKAWKVVVNLLNLIIGGSFIERNWNSSKEMFKFIIVLGSLTNVLIIMLTLLVSFFSN--KVRLDIPLDGNYTILIGFPIIYRQLLPETTIIHLKTPQFLAKNFRFKLLPIFVMFTMTVTQIIWFHHFAQLFSIWVTFFASWSYLRFFQKLAPLNCPSLPTTNSQGGQEILVGDASDTFQLIYFFPDLIKPILRPIFNFIYNVVVVKFKVIK--PFHDIDIDIGNTIAESRGAKKIMTVEERRRQLALQVLEERMVNP----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ::. : :. : . : : : * . * : . :* :. ::: : *.*.:.: .: : * ::* *. *:: *: : . ..:* . *: : : : : :.* : *. : :* : : ::: :. :*: :: : : . . : ** ****:*: . *: ** :: * : ***:: :*.: : * ::. : . ..: . .::: . . . * ****:**:.*.**: ", "identical_positions": 43, "similar_positions": 103, "identity": "8.81%" }, { "cls_id": "homologset.agr.SGD:S000005471", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P21126-1", "uniprot_id": "UBL4A_MOUSE", "id": "P21126-1", "name": "Ubiquitin-like protein 4A", "aln": "MQLTVKALQGRECS-----LQVAEDELVSTLKHLVSDKLNVPVRQQRLLFKG-KALADEKRLSDYNIGP-NSKLNLVVKPLEK---------------------VLLEEGSAHR-----------------LVDSPATPIWQLISKVLARHFSVADASRVLEQLQRDYDRSLSRLTL--DDIERLASRFLHP------EVTEAMEKGFCK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2GV38-1", "uniprot_id": "UBL4A_RAT", "id": "B2GV38-1", "name": "Ubiquitin-like protein 4A", "aln": "MQLTVKALQGRECS-----LQVAEDELVSTLKHLVSDKLNVPVRQQRLLFKG-KALADEKRLSDYNIGP-NSKLNLVVKPLEK---------------------VLLEEGSAHR-----------------LVDSSATPIWQLISKVLARHFSIGDASRVLEQLQRDYDRSLSRLTL--DDIERLASRFLHP------EVTEAMEKGFCK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11441-1", "uniprot_id": "UBL4A_HUMAN", "id": "P11441-1", "name": "Ubiquitin-like protein 4A", "aln": "MQLTVKALQGRECS-----LQVPEDELVSTLKQLVSEKLNVPVRQQRLLFKG-KALADGKRLSDYSIGP-NSKLNLVVKPLEK---------------------VLLEEGEAQR-----------------LADSPPPQVWQLISKVLARHFSAADASRVLEQLQRDYERSLSRLTL--DDIERLASRFLHP------EVTETMEKGFSK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12285-1", "uniprot_id": "MDY2_YEAST", "id": "Q12285-1", "name": "Ubiquitin-like protein MDY2", "aln": "MSTSASGPEHEFVSKFLTLATLTEPKLPKSYTKPLKDVTNLGVPLPTLKYKYKQNRAKKLKLHQDQQGQDNAAVHLTLKKIQAPKFSIEHDFSPSDTILQIKQHLISEEKASHISEIKLLLKGKVLHDNLFLSDLKVTPANSTITVMIKPNPTISKEPEAEKSTNSPAPAPPQELTVPWDDIEALLKNNFENDQAAVRQVMERLQKGWSLAK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :... : . * :.* :* .: .: :.: *: * * :* : *. :* : . * *: ::*.:* :: :: ** :: * * . . *: :: : : .. ... :. : . ..**: **** * .. :. :* * ::**:. ", "identical_positions": 30, "similar_positions": 63, "identity": "14.15%" }, { "cls_id": "homologset.agr.SGD:S000005472", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D3N8-1", "uniprot_id": "GRTP1_MOUSE", "id": "Q9D3N8-1", "name": "Growth hormone-regulated TBC protein 1", "aln": "-------------------------------------------------MDPAERA-------------QAARARVPRIDPYGFERPEDFD-YAAYEEFFSTYLVILTKRAIKWSKLLKGNGGVRK----------SVTVKRYVRKGIPLEHRARVWMAVSGAQARMDQSPGYYHRLL---EGE-SSSSLDEAIRTDLNRTFPDNVMFRKTAD----PCLQKTLYNVLLAYGLHNPDVGYCQCCAQKPGSSAGLRSSLTGMNFIAGYLILITKNEEESFWLLDALVGRILPDYYSPAMLGLKTDQEVLAELVRMKLPAVAALMDG-----------------------HGVLWTLLVSRWFICLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLIKQHQEFILEASS--------------------------------------IPDICDKFKQ-ITKGD-----FVTECHAFMQKIFSEPGSLSMTTITRLRKSCRAALQAQS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4QQU7-1", "uniprot_id": "GRTP1_RAT", "id": "Q4QQU7-1", "name": "Growth hormone-regulated TBC protein 1", "aln": "-------------------------------------------------MDPAERA-------------QAARARVPRIDPYGFERPEDFD-YAAYEEFFSTYLVILTKRAIKWSKLLKGSGGVRK----------SVT---------------------------------------------------------DLNRTFPDNVMFRKTAD----PCLQKTLYNVLLAYGLHNQDVGYCQ-----------------GMNFIAGYLILITKNEEESFWLLDALVGRILPDYYSPAMLGLKTDQEVLAELVRMKLPAVAALMDG-----------------------HGVLWTLLVSRWFICLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLIKQHQEFILEASS--------------------------------------VPDICDKFKQ-ITKGD-----FVTECHTFMQKIFSEPGSLSMATITRLRESCRAALQAQS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5TC63-1", "uniprot_id": "GRTP1_HUMAN", "id": "Q5TC63-1", "name": "Growth hormone-regulated TBC protein 1", "aln": "-------------------------------------------------MQPAE------------------RSRVPRIDPYGFERPEDFD-DAAYEKFFSSYLVTLTRRAIKWSRLLQG-GGVPR----------SRTVKRYVRKGVPLEHRARVWMVLSGAQAQMDQNPGYYHQLL---QGE-RNPRLEDAIRTDLNRTFPDNVKFRKTTD----PCLQRTLYNVLLAYGHHNQGVGYCQ-----------------GMNFIAGYLILITNNEEESFWLLDALVGRILPDYYSPAMLGLKTDQEVLGELVRAKLPAVGALMER-----------------------LGVLWTLLVSRWFICLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLIKQHQELILEATS--------------------------------------VPDICDKFKQ-ITKGS-----FVMECHTFMQKIFSEPGSLSMATVAKLRESCRARLLAQG---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PBU5-1", "uniprot_id": "GRT1A_DANRE", "id": "Q6PBU5-1", "name": "Growth hormone-regulated TBC protein 1-A", "aln": "-------------------------------------------------MEERDRTGRTGQPQHRINQPSTARERANSVDAYGFQRSDDFD-YETHEQLMSEYLAVLTRRSIRWAKLLQGRRRVDR----------NLKVKRYVRKGVPNEHRPLVWMVCSGAQEQMDRNPGYYQSLL---DTH-HEPKLEESIRTDLHRTFPDNIYFRKSAE----PCLQQALYNVLVAYGHHNKAVGYCQ-----------------GMNFIAGYLILVSKDEETSFWLMEALLSRILPDYYTPAMLGLKTDQEVLGELVRLKAPAVWKLMQD-----------------------QGVMWTLVVSRWFICLFIDVLPVETVLRIWDCLFYEGSKILFRVALTLIRHHQQEIAEAQN--------------------------------------LPDVCERFKR-ITRGA-----FVEDCHTFMQKIFQEPGSLSMATVSKLRESCRARIIADES--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEY4-1", "uniprot_id": "Q9VEY4_DROME", "id": "Q9VEY4-1", "name": "Growth hormone-regulated TBC protein 1", "aln": "-------------------------------------------------MDATASS------------------KFSDVDEYGFKRGDHFD-YNNYSKFMDGYLKTLTRRRMKWEAILQQNTDLTQV---------DAKLKRYIRKGIPGPYRPDVWMKISGAAAAQRRSPDLFRNLL---RTEPFDKEISDSISIDLPRTFPDNIHFDMK---------KQRLYNILIAYAHHNRDVGYCQ-----------------GLNYIAGLLLIVTDDEEKSFWLLKHIVENIVPQYHSHNMANLLRDLAVFRELVIRRIPAVNRHVDN-----------------------LGLPYPVIASKWFICIFAEVLPVETVLRIWDCVFAEGYKIVFRAALTMFVTHKNAILGCDD--------------------------------------IAALANLFRDTMIQDN-----IVTDCHGFVEAMFSLR--LKRSELESLRK---VAVLNPA---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12317-1", "uniprot_id": "MSB4_YEAST", "id": "Q12317-1", "name": "GTPase-activating protein MSB4", "aln": "MIMSSTMSTEAALVPNESVFDTVSSFNEDDANYSVLDLYDDDDEGDDSSTVERKEILTTRELEKAKAFTSLIMADPENFDRYGFSKKGYFISQEEYDKWWTEYNRYTERRKKKWENFLLKNKIELHNDNPLVYPARTDELSKFVRKGIPAEWRGNAWWYFAGGQRQLDANVGVYDRLKSDCREGAVSGKDMEAIERDLYRTFPDNIHFHKESFQNGEPAIIRSLRRVLMAFSVYDKTIGYCQ-----------------SMNFLVGLLLLFME-EEKAFWMLVIITGKYLPGVYESDLEGANVDQGVLVLCIKEYLPEIWSHIESSYMNGNGSTDQISGPASGEEYLCRLPTLTLCTASWFMSCFVGVVPIETTLRIWDCLFYEESHFLFKVALGILKLSESEFLESKSQKLFRQYSSYTFGGSNDSDSTFKRLKNKIKTQEEADMEILQVIQNFPKRLLNPNDIFEKVLMKKKVALNGITQEKIDRGREYVAMARNRQRASSRPKERRK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* ***.: * :.: * :* :* :* : ** ******: * : * .:*:*:. :: :**** .:*::.* *::. . ** :**:: : . :* : : . * *: : * : :: .: .: **:. * ::*:**.******:* * :::*:.** :: :. : . . : : : * : . .: . : :: : . : *: . ", "identical_positions": 55, "similar_positions": 82, "identity": "10.78%" }, { "cls_id": "homologset.agr.SGD:S000005473", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61036-1", "uniprot_id": "PAK3_MOUSE", "id": "Q61036-1", "name": "Serine/threonine-protein kinase PAK 3", "aln": "-----------------------------MSDSLDNEEK-PPAPPLR-----MNSNNRDSSALNHSSKPLPMAPEEKNKKAR-LRSIFPGGGDKTNKK-----------------KEKERPEISLPSDFEHTIHVGFDAVTGEFTPDLYGSQMCPGKLPEGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQK--YMSFTSGDKSAHGYIAAHQSNTKTASEPPLAPPVSEEEDEEEEEEEDDNEPPPVIAPRPEHTKSIYTRSVVESIASPAAPNKEDIPPSAEN-------------------------------ANSTTLYRN-------TDRQRKKSKMTDEEILEKL------------RSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQE-----------------VAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVG--DELWVVMEYLAGGSLTDVVTETCMD----------EGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIKNSSR-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62829-1", "uniprot_id": "PAK3_RAT", "id": "Q62829-1", "name": "Serine/threonine-protein kinase PAK 3", "aln": "-----------------------------MSDSLDNEEK-PPAPPLR-----MNSNNRDSSALNHSSKPLPMAPEEKNKKAR-LRSIFPGGGDKTNKK-----------------KEKERPEISLPSDFEHTIHVGFDAVTGEFT---------------GIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQK--YMSFTSGDKSAHGYIAAHQSNTKTASEPPLAPPVSEEEDEEEEEEEDDNEPPPVIAPRPEHTKSIYTRSVVESIASPAAPNKEATPPSAEN-------------------------------ANSSTLYRN-------TDRQRKKSKMTDEEILEKL------------RSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQE-----------------VAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVG--DELWVVMEYLAGGSLTDVVTETCMD----------EGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLILAAKEAIKNSSR-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75914-1", "uniprot_id": "PAK3_HUMAN", "id": "O75914-1", "name": "Serine/threonine-protein kinase PAK 3", "aln": "-----------------------------MSDGLDNEEK-PPAPPLR-----MNSNNRDSSALNHSSKPLPMAPEEKNKKAR-LRSIFPGGGDKTNKK-----------------KEKERPEISLPSDFEHTIHVGFDAVTGEFTPDLYGSQMCPGKLPEGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQK--YMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSAEN-------------------------------ANSSTLYRN-------TDRQRKKSKMTDEEILEKL------------RSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQE-----------------VAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVG--DELWVVMEYLAGGSLTDVVTETCMD----------EGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIKNSSR-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88643-1", "uniprot_id": "PAK1_MOUSE", "id": "O88643-1", "name": "Serine/threonine-protein kinase PAK 1", "aln": "----------------------------MSNNGVDIQDK-PPAPPMRNTSTMIGAGSKDTGTLNHGSKPLPPNPEEKKKKDRFYRSILPG--DKTNKK-----------------REKERPEISLPSDFEHTIHVGFDAVTGEFT---------------GMPEQWARLLQTSNITKSEQKKNPQAVLDVLEFYNSKKTSNSKK--YMSFT--DKSAEDYNSSNTLNVKTVSETPAVPPVSEDDEDDDDD----ATPPPVIAPRPEHTKSVYTRSVIEPLP-VTPTRDVATSPIS------------PTEN---------------NTTPPDALTRN-------TEKQKKKPKMSDEEILEKL------------RSIVSVGDPKKKYTPFEKIGQGASGTVYTAMDVATGQE-----------------VAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVG--DELWVVMEYLAGGSLTDVVTETCMD----------EGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLQCCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLMHAAKEATKNNH--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35465-1", "uniprot_id": "PAK1_RAT", "id": "P35465-1", "name": "Serine/threonine-protein kinase PAK 1", "aln": "----------------------------MSNNGLDVQDK-PPAPPMRNTSTMIGAGSKDPGTLNHGSKPLPPNPEEKKKKDRFYRSILAG--DKTNKK-----------------KEKERPEISLPSDFEHTIHVGFDAVTGEFT---------------GMPEQWARLLQTSNITKSEQKKNPQAVLDVLEFYNSKKTSNSQK--YMSFT--DKSAEDYNSSNTLNVKTVSETPAVPPVSED-EDDDDD----ATPPPVIAPRPEHTKSVYTRSVIEPLP-VTPTRDVATSPIS------------PTEN---------------NTTPPDALTRN-------TEKQKKKPKMSDEEILEKL------------RSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQE-----------------VAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVG--DELWVVMEYLAGGSLTDVVTETCMD----------EGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEATKNNH--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13153-1", "uniprot_id": "PAK1_HUMAN", "id": "Q13153-1", "name": "Serine/threonine-protein kinase PAK 1", "aln": "----------------------------MSNNGLDIQDK-PPAPPMRNTSTMIGAGSKDAGTLNHGSKPLPPNPEEKKKKDRFYRSILPG--DKTNKK-----------------KEKERPEISLPSDFEHTIHVGFDAVTGEFT---------------GMPEQWARLLQTSNITKSEQKKNPQAVLDVLEFYNSKKTSNSQK--YMSFT--DKSAEDYNSSNALNVKAVSETPAVPPVSEDEDDDDDD----ATPPPVIAPRPEHTKSVYTRSVIEPLP-VTPTRDVATSPIS------------PTEN---------------NTTPPDALTRN-------TEKQKKKPKMSDEEILEKL------------RSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQE-----------------VAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVG--DELWVVMEYLAGGSLTDVVTETCMD----------EGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEATKNNH--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P9X9-1", "uniprot_id": "A0A8M9P9X9_DANRE", "id": "A0A8M9P9X9-1", "name": "non-specific serine/threonine protein kinase", "aln": "----------------------------MSDNG-EVEDK-PPAPPMRNTSTMIGSSGKDSGPLNHGSKPLPPNPEDKRRKEGFIRSILTG--GGDKTN-----------------KKKERPEISLPSDFEHTIHVGFDAVTGEFT---------------GMPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKETSNNQK--YMSFT--DKGVENFNSSSAVVPKTVSETPAVATVSEDEDEEEDE----ATPPPVIAPRPEHTKSIYTRSVIEPLPPPLSTKDAATSPITNAAADGGSSSNAPSSNTNTTNTNTTNTTNTTNTTSTSAASSTNAPSTPQTTDKSRKKKMSDEEILEKLNVLRSP----SAGSIVSVGDPKKKYTRFEKIGQGASGTVYTAIDIATGQE-----------------VAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVG--DELWVVMEYLAGGSLTDVVTETCMD----------EAQIAAVCRECLQALEFLHCNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAVFRDFLNRCLEMDVEKRGSAKELLQHQFLKVAKPLSSLTPLIIAAKEAAKNNR--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8CIN4-1", "uniprot_id": "PAK2_MOUSE", "id": "Q8CIN4-1", "name": "Serine/threonine-protein kinase PAK 2", "aln": "----------------------------MSDNG-ELEDK-PPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRNK-IISIFSG-TEKGSKK-----------------KEKERPEISPPSDFEHTIHVGFDAVTGEFT---------------GMPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSN--TVKQK--YLSFT--PPEKDGFPSGTPALNTKGSETSAV--VTEEDDDDEDA------APPVIAPRPDHTKSIYTRSVIDPIPAPVGDSNVDSGAKS-------------------------------------------------SDKQKKKAKMTDEEIMEKL------------RTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQE-----------------VAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVG--DELFVVMEYLAGGSLTDVVTETCMD----------EAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLILAAKEAMKSNR--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64303-1", "uniprot_id": "PAK2_RAT", "id": "Q64303-1", "name": "Serine/threonine-protein kinase PAK 2", "aln": "----------------------------MSDNG-ELEDK-PPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRNK-IISIFSS-TEKGSKK-----------------KEKERPEISPPSDFEHTIHVGFDAVTGEFT---------------GMPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSN--TVKQK--YLSFT--PPEKDGFPSGTPALNTKGSETSAV--VTEEDDDDEDA------APPVIAPRPDHTKSIYTRSVIDPIPAPVGDSNVDSGAKS-------------------------------------------------SDKQKKKAKMTDEEIMEKL------------RTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQE-----------------VAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVG--DELFVVMEYLAGGSLTDVVTETCMD----------EAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLILAAKEAMKSNR--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13177-1", "uniprot_id": "PAK2_HUMAN", "id": "Q13177-1", "name": "Serine/threonine-protein kinase PAK 2", "aln": "----------------------------MSDNG-ELEDK-PPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRHK-IISIFSG-TEKGSKK-----------------KEKERPEISPPSDFEHTIHVGFDAVTGEFT---------------GMPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSN--TVKQK--YLSFT--PPEKDGFPSGTPALNAKGTEAPAV--VTEEEDDDEET------APPVIAPRPDHTKSIYTRSVIDPVPAPVGDSHVDGAAKS-------------------------------------------------LDKQKKKTKMTDEEIMEKL------------RTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQE-----------------VAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVG--DELFVVMEYLAGGSLTDVVTETCMD----------EAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKEAMKSNR--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KGS4-1", "uniprot_id": "A0A0B4KGS4_DROME", "id": "A0A0B4KGS4-1", "name": "non-specific serine/threonine protein kinase", "aln": "-------------------MSFTKWFKKKGGDGGSISEIGAPTNFQRHFHVSRNQETGDLEGLPAPWVRLMNSQITRDEQDKNPDAAYHAVKYYNYSI-----------------KKKEN-EVFKPFITEDVIHEESKEIENYVN-----------YKNKHKSQDPEKSDDDGSSTATETESSSGCGSSAGNSNSSSINDSSQQS-TVPLDALEEVFKELKTNLEHRETLKAAPQEPPPVPPKKSPHTIP------PKPQIKPKPRVTQKFSRTSDIRRDEDSDNQHKINTDTIIIKP----------------------------AVGAQDAGADDNPDETILRRSKEKRAQKTDAEIYVEL------------RAICNSDDPRERYKTTQEVGKGASGIVFIAADLQNESQ-----------------VAVKTIDMKNQSSKDLILTEIRVLKDFNHKNLVNFLDAYLLEPEDQLWVVMEYMDGGPLTDVVTETVMK----------ERQIACVCRETLYAISFLHAKGIIHRDIKSDNVLLGMDGSVKVTDFGFCANIEGDE-KRQTMVGTPYWMAPEVVTRKKYGKKVDIWSIGIMAIEMIEGQPPYLYETPLRALYLIAANGRPDIKSWDKLSPNLQDFLDRCLQVEVDRRATADELLSHPFLNDCSEVKALVPNIKAAKKVLRRNVXLLCNHRTARLLYA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12469-1", "uniprot_id": "SKM1_YEAST", "id": "Q12469-1", "name": "Serine/threonine-protein kinase SKM1", "aln": "MKGVKKEGWISYKVDGLFSFLWQKRYLVLNDSYLAFYKSDKCNEEPVLSVPLTSITNVSRIQLKQNCFEILRATDQKENISPINSYFYESNSKRSIFISTRTERDLHGWLDAIFAKCPLLSGVSSPTNFTHKVHVGFDPKVGNFVG---------------VPDSWAKLLQTSEITYDDWNRNSKAVIKALQFYEDYNGLDTMQFNDHLNTSLDLKPLKSPTRYIINKRTNSIKRSVSRTLRKGKTDSILPVYQSELKPFPRPSDDDYKFTNIEDNKVREEGRVHVSKESTADSQTKQLGKKEQKVIQSHLRR-------------HDNNSTFRPHRLAPSAPATKNHDSKTKWHKEDLLELKNNDDSNEIIMKMKTVAIDVNPRPYFQLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEAYIID-DEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGSPKLRHPESVSKQTKQFLDACLQVNVESRASVRKLLTFEFLSMACSPEQLKVSLKWH----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . . . : : . : : * . :* . . . .:. : : .. * : : .. . .. : .. . : : : . . . . * * : . . : : : . :: :: :*: : :: *:**** *: : : .: **:* : :.:*..*:**:.*: *:.: .: *:**:*::*:: ::*:*:***: ** ***:: . . * *:* : :* .:.*** : :*********:**. :* **:******.:: .. ** ************:*.:* *. ***:**:*** ***:**:**** * **:****** ** *.:: : :* ::**: **:::*: *.:. :** . **. . . * : ", "identical_positions": 121, "similar_positions": 140, "identity": "17.14%" }, { "cls_id": "homologset.agr.SGD:S000005474", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14197-1", "uniprot_id": "ICT1_HUMAN", "id": "Q14197-1", "name": "Large ribosomal subunit protein mL62", "aln": "MAATRCLRWGLSRAGVWLLPPPARCPRRALHKQKDGTEFKSIYSLD--KLYPESQGSDTAWRVPNGAKQADSD----IPLDRLTISYCRSSGPGGQNVNKVNSKAEVRFH-LATAEWIAEPVRQKIAITHKNKINRLG-ELILTSESSRYQFRNLADCLQKIRDMIT-EASQTPKEPTKEDVKLHRIRIENMNRERLRQKRIHSAVKTSR-RVDMD---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R035-1", "uniprot_id": "ICT1_MOUSE", "id": "Q8R035-1", "name": "Large ribosomal subunit protein mL62", "aln": "MATAWGLRWGLSRTGTLLLAPPARCARRALHRQVDGTTFQSIYSLD--KLYPESKGADTAWKVPEHAKQASSY----IPLDRLSISYCRSSGPGGQNVNKVNSKAEVRFH-LASADWIEEPVRQKIALTHKNKINKAG-ELVLTSESSRYQFRNLAECLQKIRDMIA-EASQVPKEPSKEDARLQRLRIEKMNRERLRQKRLNSALKTSR-RMTMD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A3T5-1", "uniprot_id": "A0A8I6A3T5_RAT", "id": "A0A8I6A3T5-1", "name": "Large ribosomal subunit protein mL62", "aln": "-EHGGRLGPTLEPEPSWNLVAPAARALCSPDSAQTGERHRVQEHLQPGQAVPRIQGRGYRLEGPGEPRKAGRKGRFLLLLDRLSISYCRSSGPGGQNVNKVNSKAEVRFH-LASADWIAEPVRQKIALTHKNKINKAG-ELVLTSESSRYQFRNLAECLQKIRDMIA-KASQVPKEPSKEDAQLQRLRIEKMNRERLRQKRINSTIKTSR-RMTMD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VKU3-1", "uniprot_id": "Q9VKU3_DROME", "id": "Q9VKU3-1", "name": "Large ribosomal subunit protein mL62", "aln": "----------MNKITSAFIRVLRQSSSSGGTGNLLGRQLSYKSDLSLDKIYP---GARLQIYTPPPPPSGSDKFSGFIPMDRLEITYSRSSGPGGQHVNTVNTKVDVRFK-VAQADWIPEQTRQKLLKVLANRITKDG-YFYIKSDLTRSQQMNLADALEKLRTIIRSQEAVAPAPPSEETLEKLRRRQERAVRERLQLKRGRAQVKADR-QGPSGLDL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12322-1", "uniprot_id": "YO114_YEAST", "id": "Q12322-1", "name": "Putative uncharacterized protein YOL114C", "aln": "-----------MTTLMGKFKLTGRSPLFVLQPMLHCKKQQFVEEAVR-LISNKKIGKKSDFVQARNWVGALNVTG--LPLNQFILRYDRASGPGGQNVNKVNSKCTLTLSGLSNCAWIPQEVRNILSSGRFRYYAKGSDSIVIQSDETRSRETNKLKCFEKLVQEIR-QTCQFPNDTTAETSKKWNKIKEKANKERLLDKKVHSDKKKNRSKIKFNY--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * . . : :::: : * *:******:**.**:* : : :: . ** : .*: : . : . : : *: :* : * ..::*: * : . * .: * . . *. :*** *: .: * .* : . ", "identical_positions": 31, "similar_positions": 50, "identity": "14.16%" }, { "cls_id": "homologset.agr.SGD:S000005475", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LJG4-1", "uniprot_id": "A0ABK0LJG4_RAT", "id": "A0ABK0LJG4-1", "name": "Terminal nucleotidyltransferase 4B", "aln": "MDPRIAWFQPEQLGPSNSLWMQIWETTQGLRNLYFNHHCHSSG---ASSASGGSGSGPGSPGGTAPAPAGMFRSGERPLGGLAVP---AEQRDFLPLETTNNNNNHHQPAAWARRAAAGPSASPVPSAPSSPRPAAPLPASESADPASG--------------------------------------------SSNKRKRDNKASTYGLNY------------------SLLQPSGGRAAGGGRADGGGGVYSGTPWKRR--NYNQGVVG---LHEEISDFYEYMSPRPEEEKMRMEVVSRIESVIKELWPSADVQIFGSFKTGLYLPTS-DIDLVVFG-KWENLP---LWTLEEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFN-VQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVFT-GGIGSYSLFLMAVSFLQLHPRED--ACIPNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLS-HAVSPIAKCYPNNETESILGRIIRVTDEVTTYRDWISKQWGLQNRPEP--SCNGNGVTLIVETQQL-------------DKCNNNLSEENEAPGKCRSKASESLSKHSSNSSSGPVSSSSAT---------------------------------------------------QSSSSDVDSDATPCKTP---------------------------------KQVLCRPPTVSRVGSQDVSLEVSQAVGKMQSTQTTNTANSTNKSQHGSARLFRSS---------------SKGFQG---TAQTSHGA---------------LMTSK--------QHPGKSNTQCYHGKKRRHKRDAPLSELCR--------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q68ED3-1", "uniprot_id": "PAPD5_MOUSE", "id": "Q68ED3-1", "name": "Terminal nucleotidyltransferase 4B", "aln": "----------------------------------------------------------------------MFRSGERPLGGLAVP---AEQRDFLPLETTNNNNNHHQPAAWARRASAGPSASPVPSAPSSPRPAAALPASESTDPASG--------------------------------------------SSNKRKRDNKASTYGLNY------------------SLLQPSGGRAAGGGRADGGGGVYSGTPWKRR--NYNQGVVG---LHEEISDFYEYMSPRPEEEKMRMEVVSRIESVIKELWPSADVQIFGSFKTGLYLPTS-DIDLVVFG-KWENLP---LWTLEEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFN-VQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVFT-GGIGSYSLFLMAVSFLQLHPRED--ACIPNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLS-HAVSPIAKYYPNNETESILGRIIRVTDEVATYRDWISKQWGLQNRPEP--SCNGNGVTLIVDTQQL-------------DKCNNNLSEEKEALGKCRSNASEPLSKHSSNSSSGPVSSSSAT---------------------------------------------------QSSSSDVDSDATPCKTP---------------------------------KQLLCRPPTVTRVGSQDVSLEVSQAVGKMQSTQTTNTPNNANKSQHGSARLFRSS---------------SKGFQG---TAQTSHGA---------------LMTSK--------QHQGKSNTQYYHGKKRRHKRDAPLSELCR--------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NDF8-1", "uniprot_id": "PAPD5_HUMAN", "id": "Q8NDF8-1", "name": "Terminal nucleotidyltransferase 4B", "aln": "----------------------------------------------------------------------MYRSGERLLGSHALP---AEQRDFLPLETTNNNNNHHQPGAWARRAGS--SASSPPSASSSPHPSAAVPAADPADSASG--------------------------------------------SSNKRKRDNKAS------------------------------GGRAAGGGRADGGGVVYSGTPWKRR--NYNQGVVG---LHEEISDFYEYMSPRPEEEKMRMEVVNRIESVIKELWPSADVQIFGSFKTGLYLPTS-DIDLVVFG-KWENLP---LWTLEEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFN-VQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVFT-GGIGSYSLFLMAVSFLQLHPRED--ACIPNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLS-HAVSPIAKYYPNNETESILGRIIRVTDEVATYRDWISKQWGLKNRPEP--SCNG------------------------------------------------------------PVSSSSAT---------------------------------------------------QSSSSDVDSDATPCKTP---------------------------------KQLLCRPSTGNRVGSQDVSLESSQAVGKMQSTQTTNTSNSTNKSQHGSARLFRSS---------------SKGFQG---TTQTSHGS---------------LMTNK--------QHQGKSNNQYYHGKKRKHKRDAPLSDLCR--------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1D6UPT1-1", "uniprot_id": "A0A1D6UPT1_DANRE", "id": "A0A1D6UPT1-1", "name": "Terminal nucleotidyltransferase 4A", "aln": "MDPRIAWFQPEQRGPANNLWMHIWDTTQTLGNLYFNNNCN-----------------------TASAKLTTNGDGASSNAADSSS---GRPKDQQGMSGSKPDSEVSEQQDFIPLEAFNNINSSRPGRVVGG--GGQVGGSGVAGVGNE--------------------------------------------LPSKRKRDNKASTYGFN-------------------------RSLLLTDGAEDG----YAGTPWKSR--NYSDGIVG---LHEEIKDFYEYISPRPEEEQMRHEVVARIQRVIKDLWPNAEVCVFGSFSTGLYLPTS-DIDLVVFG-NWETLP---LWTLEEALRKRKVADENSIKVLDKATVPIIKLMDSHTEVKVDISFN-VQSGVKAANLIKDYKQQYPVLPYLVLVLKQFLLQRELNEVFT-GGIGSYSLFLMAVSFLQLHCRED--VSSSNPNLGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKSMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKEAFDYAYVILS-HAVSPIAKYYPNNKSESILGRIIRVTQEVVEYRDWISAQWGQKSSKEPVLNCNANDLTLLVEREEL-------------DECNNNLSED-------------------SVVCTSVPRSKVSS---------------------------------------------------NSSSPSPSSPSSPSSSS---------------------------------SSPSSTASSSSDADSDGTPYKTAKALGGRSTYSENTERISNHRSQNHSASISTPT---------------HKGNKSRQLANKSTQGP---------------HNNPN--------KIQQSSKSVKSNVKKRKPQRDSAHEDLCR--------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6PB75-1", "uniprot_id": "PAPD7_MOUSE", "id": "Q6PB75-1", "name": "Terminal nucleotidyltransferase 4A", "aln": "MDPRVAWIQPEQKGPANALWMQIWETSQGVGRGGSGFAS-------YFCLNSPALDTAAAPGAAGRAAPAAGGPGPAPAASSPPP--APGPAALPPALLTALGPAADSARRLHKSPSLSSSSSSSSSNAESGTESPGCSSSSSSSTSLGRAGSGR--TFFSFADGA------AHAHPGPRGSTPAGSPPQHQFHPGRRKRENKASTYGLN-------------------YLLSGSRAATLSGGGGPGAQAARPGTPWKSR--AYSPGIQG---LHEEIIDFYNFMSPCPEEAAMRREVVKRIETVVKDLWPTADVQIFGSFSTGLYLPTS-DIDLVVFG-KWERPP---LQLLEQALRKHNVAEPCSIKVLDKATVPIIKLTDQETEVKVDISFN-METGVRAAEFIKNYMKKYSLLPYLILVLKQFLLQRDLNEVFT-GGISSYSLILMAISFLQLHPRID--ARRADENLGMLLVEFFELYGRNFNYLKTGIRIKEGGAYIAKEEIMKAMTSGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKQVFDYAYIVLS-HAVSPLARSYPNRDSESTLGRIIKVTQEVIDYRRWIKEKWG----SRILPSPDLDNRIKIKERIT-----------------TCNGEQMQSREPSSPYTQRLTLSLSSPQLLSSGSSASSVS---------------------------------------------------SLSGSDIDSDTPPCTTPSVYQFSLQAPTTLMASLPTALPMPSSKPQPAASRTLIMTTNNQTRVTIPPPTLGVAPVPCRQAGVDGTTSLKAVHSVTSPAIPSASPNPLSSPHL-------YHKQHNGMKLSMKGSHNHTQGGGYSSVGSGAVRPPVGN--------RGHHQYNRTGWRRKKHAHTRDSLPVSLSR--------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZSY1-1", "uniprot_id": "D3ZSY1_RAT", "id": "D3ZSY1-1", "name": "Terminal nucleotidyltransferase 4A", "aln": "MDPRVAWIQPEQKGPANALWMQIWETSQGVGRGGSGFAS-------YFCLNSPALDTAAAPGAAGRAAPAAGGPGPAPAASSPPP--APGPAALPPALLTALGPAADGARRLHKSPSLSSSSSSSS-NAESGTESPGCSSSSSSSTSLGRAGSGR--TFFSFADGA------AHAHPGPRGPTPAGSPPQHQFHPGRRKRENKASTYGLN-------------------YLLSGSRAATLSGGGGPGAQAARPGTPWKSR--AYSPGIQG---LHEEIIDFYNFMSPCPEEAAMRREVVKRIETVVKDLWPSADVQIFGSFSTGLYLPTS-DIDLVVFG-KWERPP---LQLLEQALRKHNVAEPCSIKVLDKATVPIIKLTDQETEVKVDISFN-METGVRAAEFIKNYMKKYSLLPYLILVLKQFLLQRDLNEVFT-GGISSYSLILMAISFLQLHPRID--ARRADENLGMLLVEFFELYGRNFNYLKTGIRIKEGGAYIAKEEIMKAMTSGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKQVFDYAYIVLS-HAVSPLARSYPNRDSESTLGRIIKVTQEVIDYRRWIKEKWG----SRIVPSPDLDNRIKIKERVT-----------------TCNGEQMQSREPSSPYSQRLTLSLSSPQLLSSGSSASSVS---------------------------------------------------SLSGSDIDSDTPPCTTPSVYQFSLQAPTTLMAGLPTALPVPSSKPQPAASRTLIMTTNNQTRVTIPPPTLGVAPVPCRQAGVDGTTSLKAVHNVTSPAIPSASPNPLSSPHL-------YHKQHNGMKLSMKGSHNHTQGGGYSSVGSGAVRPPVGN--------RGHHQYNRTGWRRKKHAHTRDSLPVSLSR--------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5XG87-1", "uniprot_id": "PAPD7_HUMAN", "id": "Q5XG87-1", "name": "Terminal nucleotidyltransferase 4A", "aln": "MDPRVAWIQPEQKGPANALWMQIWETSQGVGRGGSGFAS-------YFCLNSPALDTAAAAGAAGRGS---GGLGPALPAASPPPPGPTAPAALPPALLTALGPAAEGARRLHKSPSLSSSSSSSSSNAESGTESPGCSSSSSSSASLGRPGGGRGGAFFNFADGAPSAPGTANGHPGPRGPAPAGSPSQHQFHPGRRKRENKASTYGLN-------------------YLLSGSRAAALSGGGGPGAQAPRPGTPWKSR--AYSPGIQG---LHEEIIDFYNFMSPCPEEAAMRREVVKRIETVVKDLWPTADVQIFGSFSTGLYLPTS-DIDLVVFG-KWERPP---LQLLEQALRKHNVAEPCSIKVLDKATVPIIKLTDQETEVKVDISFN-METGVRAAEFIKNYMKKYSLLPYLILVLKQFLLQRDLNEVFT-GGISSYSLILMAISFLQLHPRID--ARRADENLGMLLVEFFELYGRNFNYLKTGIRIKEGGAYIAKEEIMKAMTSGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKQVFDYAYIVLS-HAVSPLARSYPNRDAESTLGRIIKVTQEVIDYRRWIKEKWG----SKAHPSPGMDSRIKIKERIA-----------------TCNGEQTQNREPESPYGQRLTLSLSSPQLLSSGSSASSVS---------------------------------------------------SLSGSDVDSDTPPCTTPSVYQFSLQAPAPLMAGLPTALPMPSGKPQPTTSRTLIMTTNNQTRFTIPPPTLGVAPVPCRQAGVEGTASLKAVHHMSSPAIPSASPNPLSSPHL-------YHKQHNGMKLSMKGSHGHTQGGGYSSVGSGGVRPPVGN--------RGHHQYNRTGWRRKKHTHTRDSLPVSLSR--------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58I0Y0-1", "uniprot_id": "A0AC58I0Y0_DANRE", "id": "A0AC58I0Y0-1", "name": "Terminal nucleotidyltransferase 4A", "aln": "MDPRVAWIQPEQKGPANALWMRVWETSQ-VNRTNTGQHQNHHHHHHNFCVNSPAFDVYKTVASNANNSTNIKNNGTAIPGSGSAVLALNGNAVDGEMSQKTGGSVVDSASSCTRIR--TTSPNVIAGNMNKGQPFFTLNESVLNNVNHHHHPPHPHLRHFHQEQQS-------CMKRHPSYPTAIHNHHHHHHHPGRRKSDNKASTYGIN-------------------YLLSN-----WTNG-----NYESSGTPWKTR--KYSPGVDG---LHEEIMDFYNFMSPRPEEATMRQEVVDRIESVIKELWPTADVQIFGSFSTGLFLPTSSDIDLVVFG-KWEKPP---LQQLEQALRKHSVAEPYSIKVLDKATVPIIKLTDQETEVKVDISFN-VETGIKAASFIKEYVKKYTVLPYLIFVLKQFLLQRDLNEVFT-GGISSYSLILMVISFLQLHPRID--TRNPNMNLGILLIEFFELYGRHFNYLKTGIRIKNGGAYMAKEDIMKAMSNGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKEAFDYAYIILS-HAVSPLARSYPNKDSDSTLGRIIKVTQEVIDYREWIIKKWGGRHNSRIERNPGSSHKEHVDQVETG-------------SLLGVGVEEQQQRDSVSPHSADSPMSLSSPQQHSS---ASSAS---------------------------------------------------SLSGSDIDSDSTPYVAPPVAPFPLQILAP--GPLPPALQMG----KASIAAALGMPPVTQARVSIPG-NLSLHTLPGRQVCMADGP--PSYLHMPPPAVPPAPPSPLPSP---------LHHPKAGPKFPLKGFHNP------AVVHS----PVLSN--------RGHIQYNRNTWRRRK----RDSLPASVSR--------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KVS9-1", "uniprot_id": "TRF41_DROME", "id": "Q7KVS9-1", "name": "Non-canonical poly(A) RNA polymerase protein Trf4-1", "aln": "MDPFVGWFQKEQEGPSLCTWLKIWETNAQEMGALLNQQLQQATTINGSTSSSSSSSNSGNNNNNNNNNIINNTITNTTNNTGNNSSAKPYLSRPYSSLNRVLNFRADSLEILQQQQQQQQLNGTTQRNSTNINTTSGGSTSSSADSTTNRDNNSPANSSSTNGPGAGTGTSTGAGGTGTNSPATTASSTAATTTGPATSMSDTSNNPPQSTTTPASRTNSIYYNPSRKKRPENKAGGAHYYMNNHMEMIAKYKGEPWRKPDYPYGEGVIG---LHEEIEHFYQYVLPTPCEHAIRNEVVKRIEAVVHSIWPQAVVEIFGSFRTGLFLPTS-DIDLVVLG-LWEKLP---LRTLEFELVSRGIAEACTVRVLDKASVPIIKLTDRETQVKVDISFN-MQSGVQSAELIKKFKRDYPVLEKLVLVLKQFLLLRDLNEVFT-GGISSYSLILMCISFLQMHPRG---IYHDTANLGVLLLEFFELYGRRFNYMKIGISIKNGGRYMPKDELQRDMVDGHRPSLLCIEDPLTPGNDIGRSSYGVFQVQQAFKCAYRVLA-LAVSPLNLLGIDPRVNSILGRIIHITDDVIDYREWIRENFEHLVVVDRISPLPTAAPTAYATANGAPKYVIMPSGAVVQQLYHHPVQVPTAHGHSHAHSHSHGHAHPGAHLCQPYVTGTTVSAVTTTTTMAVVTVGVSAGGVQQQQQQQNATAHTHSQQQTQNQSQSRHRRGSTSSGDDSEDSKDGDVVETTSSAQEVVDIALSTPNGLANMSMPMPVHAVGMPASNSWSGNGNGNGNSSSSTGSSPEIAHIAAQEMDPELEDQQQQQQHQETSGGNGFIRPGDVGTGSNRGGGDGSGGRNYNQRNNHNSSGYYHQQYYVPPPMQQQLSKSNSSSNYHQQHHHSHSHGNHSHRQQHHHQQQHHHQQRPQHLRVGGGNRYQKSLGGSPIISAGNASNSSSNCSNSSSSSGSNNSRLPPLRGTLVNSSSAISIISISSESSIASSSSSSSRSGQDQQRDER", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VC07-1", "uniprot_id": "TRF42_DROME", "id": "Q9VC07-1", "name": "Inactive non-canonical poly(A) RNA polymerase protein Trf4-2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCDEAN-----------------------------------------------PAKPWQLPDVVYGNGIPALCLLHQEIEQFYNYIRSTPTEFCLRAGAVRRIEDVVLSIWPSASVDLFGSFRTGLNLPDS-DIDLVVYYKFWNPRL---LHELQNELVSQGVTDPDTVTVLDKASVPVVKFTDLISRIRFDVTFNSVASGVQAADLIKDFIRHFPELPKLVMVLKQFLSLHGFNEVYNSGGVSSYALTLMVISFLQQHARSNR-RLSEHSKLALLLIQFLDYYGRKFDFFKYGISVLGQGGCVEKARLRSTLGENNWQSVLCIEDPVTPTNDIGRSSYGVLGVMQGFGAAFVKLS-KLVD----SDSSKIVGPILANIVEVPQSIINYRAWVHYNFQHLLTPE----LPCADS-----------------------------------------------------LVQPSPTGSTS---------------------------------------------------PSASASASEDERSG------------------------------------GPAT-------IGFGRCDDPPQNIDIVADLANLKMN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53632-1", "uniprot_id": "PAP2_YEAST", "id": "P53632-1", "name": "Poly(A) RNA polymerase protein 2", "aln": "-------MGAKSVTASSSKKIKNRHNGKVKKSKKIKKVRK----------------------PQKSISLNDENEVEILPSRNEQETNKLPKDHVTADGILVLEHKSDDDEGFDVYDGHFDNPTDIPSTTEESKTPSLAVHGDEKDLANNDD----------------------------------------FISLSASSEDEQAEQEEERE-------------------------KQELEIKKEKQKEILNTDYPWILN-HDHSKQKEISDWLTFEIKDFVAYISPSREEIEIRNQTISTIREAVKQLWPDADLHVFGSYSTDLYLPGS-DIDCVVTSELGGKESRNNLYSLASHLKKKNLAT--EVEVVAKARVPIIKFVEPHSGIHIDVSFE-RTNGIEAAKLIREWLDDTPGLRELVLIVKQFLHARRLNNVHT-GGLGGFSIICLVFSFLHMHPRIITNEIDPKDNLGVLLIEFFELYGKNFGYDDVALGSSDGYPVYFPKSTWSAIQPIKNPFSLAIQDPGDESNNISRGSFNIRDIKKAFAGAFDLLTNRCFELHSATFKDRLGKSILGNVIKYRGKARDFKDERGLVLNKAIIENENYHKKRSR-----------------------------------------------------IIHDEDFAEDTVTS--------------------------------------------------TATATTTDDDYEITNPP-------------------------------------------AKKAKIEEKPESEPAKRNSGETYITVSSEDDDEDGYNPYTL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. ** :. * ** .* :: . * :* .: *. .: .:** * : :***: *.* ** * *** ** * * * .: :: : *: ** **::*: : : ::.*::*: .*:.:*.:*:.: . . * *::::**** : :*:*.. **:..::: : .***: * * : .:**::*:: **:.*.: . .: : * *:** *::.*.*:. : : * *: *: .. . . *..::. . :: :. .. ", "identical_positions": 71, "similar_positions": 109, "identity": "7.0%" }, { "cls_id": "homologset.agr.SGD:S000005479", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1AT66-1", "uniprot_id": "MOT7_MOUSE", "id": "B1AT66-1", "name": "Monocarboxylate transporter 7", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRASGQGPQRRRRGWATRDDSAVTFRDPQPRQPAGGARALRGPDPRGPARAHQAGPLLAGARRSQHMVGGAPPRPAETGCSRSRMTQKNSKLCARANVYTQVPDGGWG-WAVAVSFFFVEVFTYGIIKSFGVFFNDLMDSFDESNS-----KISWIISICVFVLTFTAPLSTVLSNRFGHRLVVMAGGLLISLGMITASFSQRVYHMYISIGVISGLG---YCFSFLPTVTILSQYFDKRRSVVTAVASTGECFAVFAFAPAITALKEHIGWRYSLLFVGLLQLNIMVCGALLRPI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IIQGPGQSPKAVTLEPRREVQYMLENEKT-----------------------------------------RTSIDSIDSGVELTTSPKNVPSEAKMEQETRAE--------------------------------------------------------QQQTLVTA-PKHSQMKAPLLDFSVLKE-KSFICYALFGLFATLGFFAPSLYIIPLGISLGIDPDRAAFLLSTMAIAEVFGRIGAG-FVLNR---EPIR--KIYIELICVILLTASLFAFTFATEFWG-----LMLCSVFFGSMVGTIGGTHIPMLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVD--QSKIYSRAFYSCAAGMCLAAVCLALVRPCKKGLCQNSHSGENQTDRQRGKALQDIPED------------------------------FLEMDLGKCEHRAHMKMDPV------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TMR7-1", "uniprot_id": "MOT7_RAT", "id": "Q7TMR7-1", "name": "Monocarboxylate transporter 7", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQKNSKLCSRANVYTQVPDGGWG-WVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNS-----KISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLG---YCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IIKGPG-SPKAIPLEPRREVQYMLENEKT-----------------------------------------RTSIDSIDSGVELTTSPKNVPSEAKREQEVRVE--------------------------------------------------------QQQTLVVG-PKHSQKRAPLLDFSILKD-RSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMG-LVLNR---EPIR--KIYIELICVILLTVSLFAFTFATEFWG-----LMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVD--QSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPED------------------------------FLEMDLGKCEPRAHMKMDPV------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15403-1", "uniprot_id": "MOT7_HUMAN", "id": "O15403-1", "name": "Monocarboxylate transporter 7", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQNKLKLCSKANVYTEVPDGGWG-WAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNS-----RISWIISICVFVLTFSAPLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLG---YCFSFLPTVTILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGALLRPI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FIRGPA-SPKIVIQENRKEAQYMLENEKT-----------------------------------------RTSIDSIDSGVELTTSPKNVPTHTNLELEPKAD--------------------------------------------------------MQQVLVKTSPRPSEKKAPLLDFSILKE-KSFICYALFGLFATLGFFAPSLYIIPLGISLGIDQDRAAFLLSTMAIAEVFGRIGAG-FVLNR---EPIR--KIYIELICVILLTVSLFAFTFATEFWG-----LMSCSIFFGFMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQSIAGLAGPPLAGLLVD--QSKIYSRAFYSCAAGMALAAVCLALVRPCKMGLCQHHHSGETKVVSHRGKTLQDIPED------------------------------FLEMDLAKNEHRVHVQMEPV------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O70451-1", "uniprot_id": "MOT2_MOUSE", "id": "O70451-1", "name": "Monocarboxylate transporter 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MP-SEPSAPLPQPLPPDGGWG-WVVVCASFISIGFSYAFPKAVTVFFKDIQEIFNTTSS-----QIAWISSIMLAVMYAGGPISSVLVNNYGSRPVVIVGGLLCCIGMILASYSNSVIELYLTVGFIGGLG---LAFNLQPALTIIGKYFYRRRPLANGCAMAGSPVFLSTLAPFNQYLFNNYGWKGSFLILGGIFLHSCVAGCLMRPV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPSP------------------------------------------------------------------------------------NTKKSKSKVGSRHD----------------------------------------------------------STLKKASKVSTAQKVNRFLDFSLFMH-RGFLIYLSGNVILFLGIFAPIIFLAQYAKHIGVDDYNSAFLLSVMAFIDMFARPSVG-LIANT---SLIRPRIQYLFSSAIIFTGICHLLCPLATTYSA-----LVVYVVFFGLGFGSIS--SLLFECLMDIVGATRFSSAVGLTTIVECCPVLFGPPLAGKLLD--ITGEYKYLYIASGTVVLVSGTYLLIGNAINYRLLDKERKREKAKKKKSASHASREME-------------------------------ALNRSKQ-DEVTVKASNAHNPP----------------------SDRDKESNI---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60669-1", "uniprot_id": "MOT2_HUMAN", "id": "O60669-1", "name": "Monocarboxylate transporter 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MP-PMPSAPPVHP-PPDGGWG-WIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYS-----EIAWISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLG---LAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGSLMRPL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPNQ------------------------------------------------------------------------------------TTSKSKNKTGKTEDD--------------------------------------------------------SSPKKIKTKKSTWEKVNKYLDFSLFKH-RGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVG-LIANS---KYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTS-----LVLYAVFFGLGFGSVS--SVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVD--LTGEYKYMYMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQK------TRESE-------------------------------PLSKSKHSEDVNVKVSNAQSVT----------------------SER--ETNI---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N837-1", "uniprot_id": "A0A8M1N837_DANRE", "id": "A0A8M1N837-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MP-PSASTNLGYT-PPDGGWG-WAVVFGSFISIGFSYAFPKSLTIYFKEIQEYFSISYS-----QIAWVSSIMLATMYAGGPVSSILVNRYGSRPVVIAGGLMVGVAMVTASFGTSILHLYLCVGVIGGFG---LAFNLQPALTIIGKYFLVKRPMANGIAMAGSPVFLSTLAPVNQFLFDQFGWRGSFFILGGVLFNCCVAGSLMRPI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KIPV------------------------------------------------------------------------------------SKTTEDNISPQTAG------------------------------------------------------------QDESKPSGCSSKLNQFIDISLFKH-RGFLIYLVGNVLMFFGFFAPVVFLAPYAKHQGVDEYSAAFLLSIFALVDMFARPGTG-LVANT---KWIRPKIQYFFSFAVTYNGLCHLMCPLLPGYID-----LVVYAVLFGLAFGMVC--ALLFEVLMDLVGAQRFSSAVGLATIIECGPVLLGPPISGLLVD--IFMDYKYMYFACGMMMLAGGVFLFIMNYYNYRWLKKEEKQRNAEELQIFS--TKELA-------------------------------AID-----EEIKLSIEEKLKD-----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53986-1", "uniprot_id": "MOT1_MOUSE", "id": "P53986-1", "name": "Monocarboxylate transporter 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MP-PAIGGPVGYT-PPDGGWG-WAVLVGAFISIGFSYAFPKSITVFFKEIEVIFSATTS-----EVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYLCIGVIGGLG---LAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFDIFDWRGSFLILGGLLLNCCVAGSLMRPI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPEQVKLEKLKSK---------------------------------------------------------------------------ESLQEAGKSDANTDL--------------------------------------------------------IGGSPKGEKLSVFQTINKFLDLSLFTH-RGFLLYLSGNVVMFFGLFTPLVFLSSYGKSKDFSSEKSAFLLSILAFVDMVARPSMG-LAANT---KWIRPRIQYFFAASVVANGVCHLLAPLSTTYVG-----FCVYAGVFGFAFGWLS--SVLFETLMDLIGPQRFSSAVGLVTIVECCPVLLGPPLLGRLND--MYGDYKYTYWACGVILIIAGIYLFIGMGINYRLLAKEQKAEEKQKREGKEDEASTDV-------------------------------DEKPKETMKAAQSPQQHSSGDP----------------------TEEESPV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F7B3-1", "uniprot_id": "E7F7B3_DANRE", "id": "E7F7B3-1", "name": "Monocarboxylate transporter 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MA-PAVGGPVGYT-PPEGGWG-WAVVLGAFISIGFSYAFPKSITVFFKEIEVIFNATSS-----QVSWISSIMLAVMYGGGPVSSILVNKYGSRPIMILGGCLSGAGLIAASFCNTVEGLYFCVGVVGGLG---LAFNLNPALTMIGKYFYKKRPIANGIAMAGSPVFLSTLAPLNTWFFDQFGWRGSFLILGGLLLNCCVAGSLMRPI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPK---------------------------------------------------------------------------------------PQPAVKADN-------------------------------------------------------------SNSRAKERKTVVEVINGFIDLTLFKH-RGFLLYLLGNVVMFFGLFSPLVFLSNYAKSKQIPREKAAFLLSILAFVDMVARPSMG-IVANT---KWVRPRVQHFFAASILLNGVCHLLAPLSTDYTG-----FVIYAIFFGFAFGWLS--SVLFETLMDLVGAQRFSSAVGLVTIVECGPVLLGPPLLGKFND--IYHDYKYTYMGCGIVLLIGSLFLFVGMGINYKLLEREAKEESKK---------ANQQ-------------------------------DDPGKEVVEALKAAEDNAAEEA----------------------V-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O35308-1", "uniprot_id": "MOT3_MOUSE", "id": "O35308-1", "name": "Monocarboxylate transporter 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MG---AGGPRRGAGPPDGGWG-WVVLGACFVVTGFAYGFPKAVSVFFRELKRDFGAGYS-----DTAWVSSIMLAMLYGTGPLSSILVTRFGCRPVMLAGGLLASAGMILASFASRLVELYLTAGVLTGLG---LALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSMLSPLGQLLGERFGWRGGFLLFGGLLLHCCACGAVMRPP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PGPPPR------------------------------------------------------------------------------------------RDPSP-------------------------------------------------------------------HGGPARRRRLLDVAVCTD-RAFVVYVVTKFLMALGLFVPAILLVNYAKDAGVPDAEAAFLLSIVGFVDIVARPACG-ALAGL---GRLRPHVPYLFSLALLANGLTDLISARARSYGT-----LVAFCIAFGLSYGMVG--ALQFEVLMATVGAPRFPSALGLVLLVEAVAVLIGPPSAGRLVD--ALKNYEIIFYLAGSEVALAGVFMAVTTYCCLRCSKNISSGRSAEGGASDPEDVEAERDSEPMPASTEEPGSLEALEVLSPR------AGSPEQEPEEEAVPELDHESIGG----------------------HEARGQKA----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70461-1", "uniprot_id": "MOT3_RAT", "id": "O70461-1", "name": "Monocarboxylate transporter 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MG---AGGPRRGAGPPDGGWG-WVVLGACFVITGFAYGFPKAVSVFFRELKRDFGAGYS-----DTAWVSSIMLAMLYGTGPLSSILVTRFGCRPVMLAGGLLASAGMILASFASRLLELYLTAGVLTGLG---LALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSTLSPLGQLLGERFGWRGGFLLFGGLLLHCCACGAVMRPP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PGPQPR------------------------------------------------------------------------------------------PDPAP-------------------------------------------------------------------PGGRARHRQLLDLAVCTD-RTFMVYMVTKFLMALGLFVPAILLVNYAKDAGVPDAEAAFLLSIVGFVDIVARPACG-ALAGL---GRLRPHVPYLFSLALLANGLTDLISARARSYGT-----LVAFCIAFGLSYGMVG--ALQFEVLMATVGAPRFPSALGLVLLVEAVAVLIGPPSAGRLVD--ALKNYEIIFYLAGSEVVLAGVFMAVTTYCCQRCSKDIPPGPSAEGGTSDTEDVEAERDSEPMPASTEEPGSLEALEVLSPR------AGSPE--PEEEAVPDLSHESVGG----------------------HEAHGQNA----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1Q7T3-1", "uniprot_id": "F1Q7T3_DANRE", "id": "F1Q7T3-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGAVVDTGDSGVKAPDGGWG-WAVLFGCFIITGFSYAFPKAVSVFFKELIREFGVGYS-----DTAWISSILLAMLYGTGPLCSILVNRFGCRPVMMVGGLFASLGMVLASFATNIIHIYLCTGVITGLG---LALNFQPSLIMLNRYFSEKRPLANGLAAAGSPVALCCLSPLGQVLQYKYGWRGGFLILGGLLLNCCACGALMRPL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LAPKKT----------------------------------------------------------------------------------------SEVEEKP-------------------------------------------------------------------KETKPKPK-LLDFTVFKD-RGFLIYTIAASIMVLGLFVPPVFVVSYAKELGNEDTKSALLLTILGFIDIFARPTSG-IIAGL---KWVRPRCVYLFSFAMIFNGIADILGSFAKDYAS-----LVVFCIFFGISYGMVG--ALQFEVLMAIVGTEKFSSAIGLVLLVEAIAVLVGPPGAGRLLD--ATKNYMYVFMLAGCEVVLSALVLAICNLLFIKRKPQQPDPPAKMEMAITETEMEELNKAPKDDQDNGGGAENEKKQAIEPETKTTSKDEVKELESIEVDSIEVENASKKVSGPN-----------------GVAVEPESSL---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BBA0-1", "uniprot_id": "A0A8M2BBA0_DANRE", "id": "A0A8M2BBA0-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGVALDDGGCKVKAPDGGWG-WAVLFGCFVITGFSYAFPKAVSVFFKELIREFGVGYS-----DTAWISSILLAMLYGTGPLCSILVNRFGCRPVMLVGGLFASLGMILASFATSIIHIYLCTGVITGLG---MALNFQPSLIMLNRYFSEKRPLANGLAAAGSPVALCCLSPLGQVLQYEYGWRGGFLILGGILLNCCACGALMRPL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPPKSSEA--------------------------------------------------------------------------------------PGIENAPD---------------------------------------------------------------DGDKTVKPKPK-LLDFSVFRD-RGFLIYTIAASIMVLGLFVPPVFVVSYAKELGNEDTKSALLLSILGFIDIFARPTCG-IIAGL---QWVRPRCVYLFSFALIFNGITDLVGSLSKDYTS-----LVVFCIFFGISYGMVG--ALQFEVLMAVVGTEKFSSAIGLVLMLEAIAVLVGPPSAGRLLD--HTKKYMFVFLLAGIEVVLSALVLAICNFLCIKKKPEAPDAAAVESGEPVEEKNHSSPPATEEPHTPNGNSE-KPKTDLRPE-------NVTEEPTEEETFLKEEDEKEKT----------------------ITCSAESDL---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P57787-1", "uniprot_id": "MOT4_MOUSE", "id": "P57787-1", "name": "Monocarboxylate transporter 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGAVVDEGPTGIKAPDGGWG-WAVLFGCFIITGFSYAFPKAVSVFFKELMHEFGIGYS-----DTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLG---LALNFQPSLIMLNRYFNKRRPIANGLAAAGSPVFLCALSPLGQLLQDHYGWRGGFLILGGLLLNCCVCAALMRPL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VAPQVG----------------------------------------------------------------------------------------GGTEPRG--------------------------------------------------------------------PQRPPQR-LLDLSVFRD-RGFLIYAVAASIMVLGLFVPPVFVVSYAKDMGVPDTKAAFLLTILGFIDIFARPTAG-FITGL---KKVRPYSVYLFSFAMFFNGFTDLTGSTATDYGG-----LVVFCIFFGISYGMVG--ALQFEVLMAIVGTQKFSSAIGLVLLLEAVAVLIGPPSGGKLLD--ATKVYKYVFILAGAEVLTSSLVLLLGNFFCIGKR-KRPEVTEPEE-VASEEKLHKPP------------------------------VDVGVDSREVEHFLKAEPEKNGE----------------------VVHTPETSV---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B5K3-1", "uniprot_id": "A0ACD6B5K3_DANRE", "id": "A0ACD6B5K3-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGIVEDRETAG--APDGGWG-WVVLLGGFVITGFSYAFPKAISVYFKELMHDFGCGYK-----DTAWISSIILAMLYGSGPISSIMVNKFGCRPVMLVGGLLASLGMISASFATSIIHLYITAGVITGLG---LALNFQPSLIMLGAYFDKRRPLANGLAAAGSPVFLSALSPLGQLLLDQYGWRGGFLITGGLLLNCCTCGAVMRPL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLKERKACNQELK---------------------------------------------------------------------------EMLPPEAGQENIVC---------------------------------------------------------------ENNNDKKPSKKKLLDFSVLRD-KGLIIYIIAKFIVVLGLFVPTILLVNYAKDQGVPDKEAAFLLSIIGFIDIFARPTCG-VVAGL---KWVRPKMSYFFSLALLFNGLTDVCSATSTDYKG-----LIIFCVFFGLSYGMVG--ALQFEVLMGIVGTSKFSSALGLVLLFEAVAVLIGPPSAGYLVD--KYKNYELIFYMAGGELITAGIFLALASFCCISQK-KRKDSP-----------------------------------------------------QTQQTYVEVNPER-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "G5E8K6-1", "uniprot_id": "MOT6_MOUSE", "id": "G5E8K6-1", "name": "Monocarboxylate transporter 6", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARALEQADGRWA-WVVLLSSLVTQALTLGFPTCIGVFFTDLQRDFQASNS-----ETSWFPSILGAMVHGGGPLCSILVKHFGCRVTMMLGGVLASLGMVVSTFSGSLTHLFLTAGVITGLG---MCFSFQSSITVVGLYFVRRRPLANALASMGLSMGVTLWPLLARYLLETLGWRGAFLIFGGILLHCCVCGALLRPV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATNEVP------------------------------------------------------------------------------------EPKEDPLLPPKIP--------------------------------------------------------TRSCLA----TCVSTIRYHLAFDILRHNMGFCIYVTGVTWMNLGFALPHIFLVPYAMHHGVDDYWAAMLMSIVGFCNIFLRPMAGLLLAGR---KSLAAYRKYLFAVAILINGLTNLICTVSADFRV-----LLGYCLVYSLSMCGVG--ILVFQVLMDIVPMDRFPSALGLFTILCGVTSLISPPLAGLLLD--KTNNFSYVFYMSSGFLVSGSLILGVGFYAAEKKK-LKQDGQAKMENATSEMTPMHDL-------------------------------TSEDKD-------SAKKQP------------------------YPESIYMTNV---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A3B5-1", "uniprot_id": "D4A3B5_RAT", "id": "D4A3B5-1", "name": "Monocarboxylate transporter 6", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQALEQADGRWA-WVVLLASLVTQALTVGFPSCIGVFFTDLQRDFQASNS-----ETSWFPSIMGAMLHCGGPLCSILIKRFGCRVTMMLGGVLASLGMVASTFSDSLIHLFLTAGLITGLG---MCFSFQSSITVVGLYFVRQRPLANALASIGISMGVTLWPLLARYLLETLGWRGAFLIFGGIFLHCCVCGAMLRPV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATNVDP------------------------------------------------------------------------------------EPKEDLLLPPKTP--------------------------------------------------------TRSCLA----TCVSTIQYYLAFDILRHNMVFCIYVTGATWMTLGFSLPHIFLVPYAMHHGMEEYWAAMLMSIVGFCNIFLRPVAG-MLAGR---KSLAAYRKYLFAVAILINGLTNLICTVSADFRV-----LLGYCLVYSLSMCGTG--ILVFQVLMDIVPMDRFPSALGLFTILCGMGSLISPPLAGLLLD--TTNNFNYVFYMSSGLLISASLFMGVGFYVAEKK--LKQDRQAKMEDATSEITSKHSL-------------------------------TSEDKD-------SAKKQP------------------------YPENIYVTSV---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15375-1", "uniprot_id": "MOT6_HUMAN", "id": "O15375-1", "name": "Monocarboxylate transporter 6", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQALERADGSWA-WVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNS-----ETSWFPSILTAVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLG---MCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATSVAP------------------------------------------------------------------------------------ETKECPPPPPETP--------------------------------------------------------ALGCLA----ACGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAG-LMAGR---PAFASHRKYLFSLALLLNGLTNLVCAASGDFWV-----LVGYCLAYSVSMSGIG--ALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLD--ATNNFSYVFYMSSFFLISAALFMGGSFYALQKK---EQGKQAVAADALERDLFLEAK-------------------------------DGPGKQRSPEIMCQSSRQPRPAGVNKHLWGCPASSRTSHEWLLWPKAVLQAKQTALGWNSPT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FB53-1", "uniprot_id": "E7FB53_DANRE", "id": "E7FB53-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPQQPSSMEEQSGELCEPESEELEKQGPGPPSNANAPDSYDAPDGGWG-WVVLLATIIVLALTLAFPSCIIIFYLDLQKEFEATNS-----QTSWVPSIMTAVLHAGGPLCSVLVDRFGCRATVMFGGVLSGFGMAVSSFSHSIVDLYITAGVITGLG---FCFSFQPAVTILGHYFVRRRPFANAMSSTGTALGLSTLPFLCDFLKIELGWRGSFLVLGAVLLNCCVCGAVMRPI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RPRKPR------------------------------------------------------------------------------------KTNEINNSPKTSD--------------------------------------------------------KKGCMLGICQSLASSLRQQMAFDLFCSNTRFRVFSLGITWMMLGFVVPLIYLVPYASADDMDPSRAALLLSILGFVNIFVRPPVG-VLFSL---PWFKGRHIYVFSAALLINGLSNSICCISASFPV-----LLVYVLTYGLSMSVVG--SLMFTVLMDTVEMSRFPSALGLLSIMESVTLLIGPPLAGFLVD--RTQLYTYVFMACTIIVVLSALFLMFTFYWLDSRDAAKKDSPAKPAINISTDCQYSSV-------------------------------PIDGDK---------TNKP------------------------SSETENTTCV---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BGC3-1", "uniprot_id": "MOT12_MOUSE", "id": "Q8BGC3-1", "name": "Monocarboxylate transporter 12", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTKITRVSLASPPDGGWG-WMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDYS-----QTAWIHSIVDCMTMLCAPLGSVVSNQLSCQAGIMLGGLLASTGFILGSFATSLKHLYLSLGVLTGLG---FALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLKEDRSVPE------------------------------------------------------------------------------KNHNRESQREDCKQA--------------------------------------------------------SPYSPLTKECTETRLCCSLQQEYGFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHHQAAFLMSILGVIDIVGNITFG-WLTDR---RCLKNYRYVCYLFAVALDGLCYLCLPMLQTFP-----LLVPFSCTFGYFDGAYV--TLIPVVTAEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGWLVD--TTGSYTAAFLLCG-FAMIFSSILLGFVRIVKRMKRTQVPFPVKDSDPKLQLWTNGSVAYSV---------------------------ARELDQKDEEPLPKARSGCNLT----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZSM3-1", "uniprot_id": "MOT12_HUMAN", "id": "Q6ZSM3-1", "name": "Monocarboxylate transporter 12", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSGSHWTANSSKIITWLLEQPGKEEKRKTMAKVNRARSTSPPDGGWG-WMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYA-----QTAWIHSIVDCVTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTGLG---FALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLKEDHTTPE------------------------------------------------------------------------------QNHVCRTQKEDIKRV--------------------------------------------------------SPYSSLTKEWAQTCLCCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAFLMSILGVIDIIGNITFG-WLTDR---RCLKNYQYVCYLFAVGMDGLCYLCLPMLQSLP-----LLVPFSCTFGYFDGAYV--TLIPVVTTEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVD--TTGSYTAAFLLCG-FSMIFSSVLLGFARLIKRMRKTQLQFIAKESDPKLQLWTNGSVAYSV---------------------------ARELDQKHGEPVATAVPGYSLT----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q503M4-1", "uniprot_id": "MT12B_DANRE", "id": "Q503M4-1", "name": "Monocarboxylate transporter 12-B", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQEKKKGGVLPPDGGWG-WMIVAGCFVVTVCTRAVTRCISIFFVEFQMHFAKDYS-----GTAWIHSLVDCTTMLCAPLGSLIGNQLSCRIAVILGGFLASVGLVLSSFATSLEYLYATLGLLTGLG---FALCYTPAIAMVGIYFCERKALAYGIAMSGSGIGTFILAPVVQLLIEHYSWRGALLILGGFVLNLCVCGALLRPI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILKEEEACPLPV----------------------------------------------------------------------------DSECGYSVKPPTLNG--------------------------------------------------------GPTRSAASDAKQR--CFQSMQEYHFLLMPDFLVLAGSFLLLASGCSLPFVYLVPYALDVGVGHQHAAFLMSILGVIDIVGNITFG-WLTDR---RCLKKYRNICYMFAVGMEGLCCLFIPLLRTFV-----WLVPFSVLYGYFDGAYV--ALIPVVTSDVVGRQYLSSALGVVYFLHAVPYLVSPPIGGWLVD--TTGTYTATFFLSG-FALISSSLLLFSVAIIRYCQRNQKKNSLS-KIPKLVSCEGKQVDYYP---------------------------PKNKDLMLIIPATS------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5NC32-1", "uniprot_id": "MOT11_MOUSE", "id": "Q5NC32-1", "name": "Monocarboxylate transporter 11", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTPKPAGPPDGGWG-WVVAAAAFAVNGLSYGLLRSLGLALPDLAEHFERSAQ-----DTAWVSALALAVQQAASPVGSALSTRWGARPVVMVGGVLTSLGLVFSAFARSLLHLYLGLGLLAGSG---WALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQFLLDTFGWRGALLLLGAVTLHLTPCGALLRPL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALSGDPLAPP--------------------------------------------------------------------------------------------R--------------------------------------------------------TPLAALG---------------LGLFKRRAFSVFALGTALIGGGYFVPYVHLGPHALDQGMGGYGAALVVAVAAVGDACARLASG-WLADQ---GWVPLPRLLVVFGSLTGLGVLAMGLVPTVGTEEGWGAPLLAAAGAYGLSAGSYA--PLVFGVLPGLVGIGGVVQATGLVMMLMSLGGLLGPPLSGFLRD--KTGDFSASFLVCSSFILSGSFIYMGLPRALPSCRPASPPATPPPERGELLPVP--QVSLLS---------------------------AGGTGSIRDTTC--------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCK7-1", "uniprot_id": "MOT11_HUMAN", "id": "Q8NCK7-1", "name": "Monocarboxylate transporter 11", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTPQPAGPPDGGWG-WVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQ-----DTAWISALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFG---WALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGALLLPL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VLPGDPPAPP--------------------------------------------------------------------------------------------R--------------------------------------------------------SPLAALG---------------LSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCG-WLADQ---GWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYA--PLVFGVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRD--ETGDFTASFLLSGSLILSGSFIYIGLPRALPSCGPASPPATPPPETGELLPAP--QAVLLS---------------------------PGGPGSTLDTTC--------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W509-1", "uniprot_id": "Q9W509_DROME", "id": "Q9W509-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVHG---PPARRKSQQQ-------HEACEMDMERQP-----------------------TPPDGGWG-WVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKG-----YTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLG---FGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPL----------------------------------------ELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLP---------------------KDQYLQLPQRTDTAVSGGALCRS----NSVGHNLKPNLNNNSN----------GAVNGQGPTLVT------------PPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRE----RSASGTMYRP----DALYQGSLHNLPDYVSS------RNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEA--------------------------------------------------------KCCGCITCSKETRDTFAEMMNFSLLKD-MVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRIILG-YISDKPWVN-----RLLVYNVCLTACGVSTAMVPLCHDFQS-----LAFYCCVFGFTIGAYVG--LTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYD--LTDSYAPAFLMAGLMIAISGLVMFAIPPLQRLQVRKSERKPHTEHLALS-----------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0L6-1", "uniprot_id": "Q9W0L6_DROME", "id": "Q9W0L6-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVDTNSSNPGIVGGNSASSARLRRFERTDSELACEEAARLTAEQSPEDEDNQDNDEDDDDEESVYGELPPPPDGGYG-WVICFASFMCNMIVDGIAYTFGIFLEEFVAYFHEGKG-----TVAWVGSLLSGVYLSAGPIVSALANKYGCRAVCIAGSIIACIAFVLSTFSTNVSMLMATYGFMGGFG---FGMIYLPAVVAVGYYFETKRSLATGIAVCGSGFGTFAFAPLATYLLEEYGWKNALLIFAGLILNCAIFGAMMRPLTYPKKKKQKPLMQRMYEEKQLQLERGSFAGSHFMVQLPDGTIERKLKMPLNADPGVHSSLNLELLAQQAGGGGLHPVSTLPTITESKVVDVHRQNGAQSPPNGDSNGQLSARSAAGAVGRRPHRNSESENSPYHSQDAMTRNASQPAFLAGDHQSLPKNGSVPAFNTRVRKTSASERFQPSLAAIRATSRGDLEAGAGGDFASSKLSLSQRQGGSQTGSSGRMVRPMSRKDIFYSGSVTNLPQYQSQKSLANYRNSVLSLTKYEKSMQSVAKLDPLAEAEKHREEY--------------------------------------------------------DLCPCLGIPDSVKSVVNTMLDVSLLKD-PVFMLIGVSNIFGMAGLYVPFVYLVDAAKEHDIPKNDAAMLLSIIGITNTVGRVFCG-WVADLPQVN-----SLLLNNCCLLVSTIAVTLTPLCYSYAA-----YITMSIFFGLAISGYIS--LTSIILVDLLGLDKLTNAFGLLILFRGFAALIGTPLAGAIYD--MTHTYDLPFYMAGALFGISTITSFLAPCLKRCSPSE-ETPVHVETLTPIDEEQGEDAEDDEDQPITIVP----------------KIIKTLASPQQEEGHPQFPQKTSESKL--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3U9N9-1", "uniprot_id": "MOT10_MOUSE", "id": "Q3U9N9-1", "name": "Monocarboxylate transporter 10", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVPSQE-----EPAAERETNEAQPPGPAPSDDAPLPGPGPSDVSDVAAEKVEVELTRSAGSE-------PPVPPEGGWG-WLVMLAAMWCNGSVFGIQNAYGVLFVSMLDTFKAKDDDNMAFKTAWVGSLSMGMIFFCCPIVSVFTDMFGCRRTAVVGAAVGFIGLMSSSFVSSIEPLYLTYGIIFACG---CSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLGNLISSVKLFNTLRILCIFMFVLFLAGFTYRPLVP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STKEKES--------------------------------------------------------GGSRSSFFSRRKLSPPKKVFNFALFKE-TTYAVWAAGIPLALFGYFVPYVHLMNHVKERFQDVNNKEVLFMCIGITSGVGRLLFG-RIADY----LPGVKKVYLQVLSFFFIGLMSMMIPLCSAFGA-----LIAVCLAMGLFDGCFIS--IMAPIAFELVGPQDASQAIGFLLGFMSIPMTVGPPIAGLLHD--KLGTYDVAFYLAGIPPFVGGVVLCLIPWIHSKKQRKISKNAGGEKMEKMLENQSS---------------------------------LLSGSSGIFKKDSASII---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TF71-1", "uniprot_id": "MOT10_HUMAN", "id": "Q8TF71-1", "name": "Monocarboxylate transporter 10", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLSQE-----EPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVELAGPATAEPHE----PPEPPEGGWG-WLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACG---CSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCIFMFVLFLAGFTYRPLAT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STKDKES--------------------------------------------------------GGSGSSLFSRKKFSPPKKIFNFAIFKV-TAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLFG-RIADY----VPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGA-----LIAVCLIMGLFDGCFIS--IMAPIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRD--KLGSYDVAFYLAGVPPLIGGAVLCFIPWIHSKKQREISKTTGKEKMEKMLENQNS---------------------------------LLSSSSGMFKKESDSII---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O70324-1", "uniprot_id": "MOT8_MOUSE", "id": "O70324-1", "name": "Monocarboxylate transporter 8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALPSPASEEAEGPCQEANQEYQEPVCSPVPEPEPEPEPEPEPDPEPVPVPPPEPQP-EPEPQPLPDPAPLPELGFEAEPVQEPEPTPTVETRGTARGFQPPEGGFG-WIVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNR-QVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATTGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCG---CSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIKMLGDKIKLAQTFQVLSTFMFVLTLLSLTYRPLLP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSQDTPS--------------------------------------------------------K-RGAHTLRQRFLVQFRKYFNMRVFRQ-RTYRIWAFGIAAAALGYFVPYVHLMKYVEDKFKEIKETWVLLVCIGATSGLGRLVSG-HISDS----IPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGG-----LIVVCLFLGLCDGFFIT--IMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRN--CFGDYHVAFYFAGVPPIIGAVILFFVPLMHQRMFKKEQRDSSKDKMLSHDPDPNGE--------------------------------LLPGSP----TPEEPI----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VWK0-1", "uniprot_id": "Q9VWK0_DROME", "id": "Q9VWK0-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKKVYQDT--TRPLPRVSRARYY---NKHDKSDLGDDFVAPDAGWA-WIVCVAAGVSNLSIYPCLQQFGFLFRERLSDLGMSSS-----QITAIINANPAVSACTGLLNGPMFRRFTFRQVAMAGSLLISGSLILTAFCETFLSYMVAYALLFGFG---MGISVSASSLAINTYFQKKRRRAAGFSWTITGLGPIFLPHLVTFLLTIYGVQGTTLLFAAISLHSFVCALIYQPVRYHVKPP-------VEQLADQEQ-QAEALCAHCSWQ------------------------------------------------------------------------------------------------------------------------------------------QKREPGGIFSSQYLCQDDDA-QRPGYEICEPGTPMLSRANDGWYGSRLSLTSG---------RLRFRTISSSKDLEQTQRLHCPISEE--QNHESDEFLRPNNFRRERVESN-------------LEAKLCCQCSAKREEHNNNRKEKEA-----------EAEEAGMESAPLHDPQMSFLAKVVTFFDLDLLRDFTFVNLVAGLTIINFGELNFSILTP-FILVDFGFDTPQITLAMSLLAGLDITMRFMVP-FLTEK-----IPWDNRVFFLIGVVGIALGRTVVACTRSYSL-----ILCSFVWIGLCKGVRT--IFWPLIIPGYVPLNRLPGASGLQLLISGLFTLIGGPFVGLVRD--RYD-YSVTLHCLNMMSFVAATSWSLEALIRRHR-RKQRLVNS------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V3F9-1", "uniprot_id": "Q9V3F9_DROME", "id": "Q9V3F9-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKSSLTEKNHTQVYNDTTKPKKP---KRRDKSDLGPDFVAPDGGWG-WVVCLAAGLNNFFLFPALQQYGLIYRVRMQSLGFDAK-----QTTTIVNVVMAISSLVGIVNGAMFRRFTFRQVALTGTSLAFLGVFLSAFCTTFWQYIICLSAIFGIG---LGLAMAATSLAVNTYFKLKRRRATGFSWTITGLGPIFFPQVSTVLLGYYGAQGTILIYAGIAMNAILCALTLQPVLWHVKKPEKPVHNTIEGIAETEKLQPELLEANGNLLSPS-------------------------------------------------------------------------------------------------------------------------NDPWKDYECKYCQYQKRSKRGLFSSQYLFNVDDP-ERPGYEITEPGTPMLARANDGWFGSKLSLTSESAGGARSRTRQALMRQVSSRSRENLDRLEQNRHDQGPDTPSAAALYKPNYFNREREDLDRYASKTSVYSRPGQDELLRCTCAEDKALLQKTAESLQVNL--------FNNSADNTEAEEEAKRRMTFFQKVSKFFDLDLLRDFTFVNLAVGMSIMMFGEMNFSVLTP-FILNSFGYTDTQISLVMSLLACMDISVRFLAP-LALEK-----VKLDNRVLFAFGILCIAVGRVVVAFTDSYEI-----MIGVFLLIGFGKAFRT--IFSPLIIPSYVPLNRLPAASGLQLIFNTIFSFAMGPILGILTE--AYG-YAATIHTINALTLLALLLWLAESVVRRILGIPSKGLGQ------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWJ0-1", "uniprot_id": "Q9VWJ0_DROME", "id": "Q9VWJ0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDNGNNHNNNNNNNNDEALRLRLPEEQAEQLLPKNGSAGQTKIAPPTHTHSIAAASVPQKVPAKKKRDKSDLGEDFVAPDGGWG-WLVSVASGVNILVTFALAQQFGILFRDRMAGLGISSS-----ELTTIINTQIAVSAFTGLLNGPLFRRYTYRVVALVGSVLTFLGLFWMVFADTFAVYIMSFSILYGFG---RGLTVSASSLAVNTYFKVKRRTATAFQFGVAGLGPIVCPYFATYMLYEFGVQGTTLLFAGASLHTIACSLIYQPVKWHVVKR------------------------------------------------------------------------------------------------------------------------------------------------------------------------DRDAEALQQVQPLAEREDQDEDIIKNVVEPETPVLPRANDGWFGSRASLNSVG-----TRNRLNTWEKSDSNGHVELKRLSS-------KDSNPGRQLRSISVSHSIKEEE------------------ATGYNSDHEVQHTELTEKEK-------------QELEDEKERQRRKKLPFYMKVVIFFDMDLLRDITYVNLAVGITLINFVEINFAILTP-FILSDLGFNKDQIALAMSTLGFFDLVVRFLIP-LITAK-----INLSNRTFFVVGILGMCIGRMFLSMTSNFYV-----MMAIFLWLGLNKAFRT--VFWSLIIPSYVPLKRLPAAAGLQLLMSGTFSMIFGPLIGLIRD--HTS-YAVTLNLLNALCVMAFAGWYLEDFIRARS-RKSPPVKSIN----------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWJ1-1", "uniprot_id": "Q9VWJ1_DROME", "id": "Q9VWJ1-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASKQPRKVAPDGGWG-WVACFGVSLVNLATRSIEPSFGLLFGDTLKELNVGTT-----GAAVIISALDVCMNFSGLFVGPLLKEFSYRKVAIAGSLLCGLGLALTSPATSMAHILSTYSVINGIG---VGLSTSAAFVALNHYFKHKRGQAVGLSMAGTAMGMLIMPQLVRILLEAYDFRGAVLLLAGVALNATVGSVLLQPVKWHMKEEFDDEELMCISALPTPQPQLTVGGAGGAASAGAPVFKVI----------------------------------------------------------------------------------------------------------------KEDGNEEDALPEMNTLLFHKPHPHQHSMRKNYSEMAMNTMNGSRLGIPKRPTFPRIMSLAGVQSAAHGAGGD----SGGYTSQAEVNATQLRCRKASVTSNLSYMDFTGSILQVHLNTGDDEFEQNDRE-----------------LRRVGTATGSIVLGGHRDSFIKMKPTELDKQAEAAAALDEEAKKKAKKPGFWRRFADLLDIDMLKDKMFLNLLFGLSIFYVAEMNFKMVTP-FFFANLGYQKTDVAFCLSITAITDIAARIVLP-PIFDR-----TTIKKRTIFLVSIIFVALTRSIMAEQTEWTQ-----LMIWLSICGFFRGSAL--SNFTLTVSEYCSLEKLPSAFGWHLVGKALFVITFGPLIGLIRD--VTDSYPICIHTQSVCIMICATAWGIEYLVEYIQSRRRTADAAQLPTQDVGATTTATSDQNDVKL--------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E960-1", "uniprot_id": "Q0E960_DROME", "id": "Q0E960-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDVQSSRVVPDGGYG-WIVVAAVALINMTNQSILSVFGQLFVGELQKMQEDTF-----TAALITNLNSLALNFSGLFIGPAIKSFKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFG---LGLISPSTFMAINSYFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFGAAFLKPLN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPAKHNNRK----------------------HIRLLTEADGEK-------------------------------------------TSPLQVVIVPTNQSKIERSPPN-----------------VDTLCSRMG-------------------------------------------QRLVQAMDLELLKDLVFWSIIVGMALVYTATINFTMIFPGFLGQTAQLNSQMVAFCMSLVAGADIVFRLLLP-IVTDH-----LRIPYRVVFLIGIVGLFVARCVLAENQTLPV-----IITMSVLTGMMKSATV--INNNLTISAHCRSEKLAGGLGLSMMSKGVIVITVGQLLGWVRD--YADSYLICLYAQGVILLVVVLVWTPEILYRHR--RQRCATNKSMETQSIDAAEVAKLNS-------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4LFF4-1", "uniprot_id": "A0A0B4LFF4_DROME", "id": "A0A0B4LFF4-1", "name": "", "aln": "MSRNRRRSFPSSQYEDKTAAAQPSGSSLRSQSLSRLDISVQNSSIYYNDTRNTRPQMVSVAVGTVSTDILNGRTSFLSLSQSHGSEVDLPSFYESFNPTFLPKLPIRRFPHMLVGASNEPEISKNQPAIPPSRPIEPISEVPFVEPAFEKKYSRTRGFSKELSTHRDNENEYIESTDEVSQMLSFTSYTDEYDRAEPLITKTQKFYKKRSPLIPKYDSEDSYVVPKETDQQESGLSFNVTTVQLADTASPESFSEYDGNRTRKQSFDMESKNSKESFDFSRGGRRLGSGMVFIYMVIPPDGGFG-WVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSIS-----SVSFVASVQIGCYFTSGAFSAVLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGITLSMIWASSQLIVGYYFERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAYVEVAPTQVGMYHLPGSSDTSSDEYYG--------------------------------------------------------------------------------------------------------------------------------------NFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCPSCSNCCWRRRKKSQNADEQNLLIRPAPLEREDLFYTGPAEYEKPHSKENVDGKEFLLMGSDKNTQQVNYGIKNIRVDDEPDRISRVHRERR---------------------------------------------------WSNENQKKQNSCRNSRFMLTVLKLFDYRLLKQ-FEFKILVASAFLFPMGFNIPFVYSSARTT---IPVEYARMIGPIIGISNLVMRNILGILAYKR------RSWTLGLCGCGLIFGGVSVLISAFYGENLI-----WFQFLYGFSYAVAPAVYSTLRGLIYVKYLGLSKLTNAFGITSLAMGMGAFIGTTIAGKLIG--ITGNYSAAFCFAGLCLIVSGFLKLLLPLLIKCRNRMAQ----------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08268-1", "uniprot_id": "MCH4_YEAST", "id": "Q08268-1", "name": "Probable transporter MCH4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLNIPIIANSKRFLFSKDHEAQSTRDHDVELETREGPSSGYNPNFNAADAILKKNSDQVDLDVNKLTNVTSRVLNTPEASLIYDDDREFPDGGLKAWLVVFGAFMGLVPVFGLINSLGAIESYISKHQLANIS---SSTISWIFSLYLAISFLSCILSGGYFDRNGSIGLMCTGTVIYAGGLFALANCKSVWQFILAFSVCSGLG---TGILMTPLIGTVATWFLKRRGIATSISTMGGSIGGIVFPIMLRKLYKEVGFQWAIRILSFICLTCLICASVLARER--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TKPVVQP------------------------------------------------------------FKSKAEVAKWYISSVFNWRYFLE-GKFLFVAIGASFAESSLTSCATYLASYSMTRGNTENVAYTMITASNAVGILGRYIPG-YFADK----FIGRFNVEIITISMAALFNFVMWLPFGGNTKV-----LWAYVCLWGFSTGSILS--LTPVCIGQISKTTDFGKRYATVYLLQALVTIPVLPIGGTLIGKGTVANYNHFIIFNSALMAAGAACYIISRHICVGAKLCKF----------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:. * : . . * . . * : . : :* . . . : : . . . . * . : ", "identical_positions": 5, "similar_positions": 23, "identity": "0.42%" }, { "cls_id": "homologset.agr.SGD:S000005480", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P12001-1", "uniprot_id": "RL18_RAT", "id": "P12001-1", "name": "Large ribosomal subunit protein eL18", "aln": "MGVDIRHNKD-RKVRRKEPKSQDIYLRLLVKLYRFLARRTNSTFNQVVLKRLFMSRTNRPPLSLSRMIRKMKLPGRENKTAVVVGTITDDVRILEVPKLKVCALRVSSRARSRILKAGGKILTFDQLALESPKGRGTVLLSGPRKGREVYRHFGKAPGTPHSHTKPYVRSKGRKFERARGRRASRGYKN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35980-1", "uniprot_id": "RL18_MOUSE", "id": "P35980-1", "name": "Large ribosomal subunit protein eL18", "aln": "MGVDIRHNKD-RKVRRKEPKSQDIYLRLLVKLYRFLARRTNSTFNQVVLKRLFMSRTNRPPLSLSRMIRKMKLPGRENKTAVVVGTVTDDVRILEVPKLKVCALRVSSRARSRILKAGGKILTFDQLALESPKGRGTVLLSGPRKGREVYRHFGKAPGTPHSHTKPYVRSKGRKFERARGRRASRGYKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07020-1", "uniprot_id": "RL18_HUMAN", "id": "Q07020-1", "name": "Large ribosomal subunit protein eL18", "aln": "MGVDIRHNKD-RKVRRKEPKSQDIYLRLLVKLYRFLARRTNSTFNQVVLKRLFMSRTNRPPLSLSRMIRKMKLPGRENKTAVVVGTITDDVRVQEVPKLKVCALRVTSRARSRILRAGGKILTFDQLALDSPKGCGTVLLSGPRKGREVYRHFGKAPGTPHSHTKPYVRSKGRKFERARGRRASRGYKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VS34-1", "uniprot_id": "RL18_DROME", "id": "Q9VS34-1", "name": "Large ribosomal subunit protein eL18", "aln": "MGIDINHKYD-RKVRRTEPKSQDVYLRLLVKLYRFLQRRTNKKFNRIILKRLFMSKINRPPLSLQRIARFFKAANQPESTIVVVGTVTDDARLLVVPKLTVCALHVTQTARERILKAGGEVLTFDQLALRSPTGKNTLLLQGRRTARTACKHFGKAPGVPHSHTRPYVRSKGRKFERARGRRSSCGYKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX49-1", "uniprot_id": "RL18A_YEAST", "id": "P0CX49-1", "name": "Large ribosomal subunit protein eL18A", "aln": "MGIDHTSKQHKRSGHRTAPKSDNVYLKLLVKLYTFLARRTDAPFNKVVLKALFLSKINRPPVSVSRIARALKQEGAANKTVVVVGTVTDDARIFEFPKTTVAALRFTAGARAKIVKAGGECITLDQLAVRAPKGQNTLILRGPRNSREAVRHFGMG---PHKGKAPRILSTGRKFERARGRRRSKGFKV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* : . *. :*. ***:::**:****** ** ***: **:::** **:*: ****:*:.*: * :* . :.* *****:***.*: .** .*.**:.: ** :*::***: :*:****: :*.* .*::* * *..* . :*** . **. . * : *.*********** * *:* ", "identical_positions": 90, "similar_positions": 55, "identity": "47.62%" }, { "cls_id": "homologset.agr.SGD:S000005481", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CZX8-1", "uniprot_id": "RS19_MOUSE", "id": "Q9CZX8-1", "name": "Small ribosomal subunit protein eS19", "aln": "MPGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDEN-WFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVRPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17074-1", "uniprot_id": "RS19_RAT", "id": "P17074-1", "name": "Small ribosomal subunit protein eS19", "aln": "MPGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDEN-WFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVRPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P39019-1", "uniprot_id": "RS19_HUMAN", "id": "P39019-1", "name": "Small ribosomal subunit protein eS19", "aln": "MPGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDEN-WFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZSH6-1", "uniprot_id": "D3ZSH6_RAT", "id": "D3ZSH6-1", "name": "", "aln": "--GVTVKDFNQQEFIRALAVFLKKSGKLKVPEWVDTVKLVKHKELAPYDEN-WFYTRAASTARHLYLRGGAGVGSVTKIYGGWQRNSVRPSHFSRGSKSVARRVLQASEGLKMVEKDQDGDHKLTPQGQRDLGSPD---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7KS38-1", "uniprot_id": "RS19B_DROME", "id": "Q7KS38-1", "name": "Small ribosomal subunit protein eS19B", "aln": "MPGVTVKEIDQHVLTKNMAAFLKKSGKIFVPEQAVYMKTGKFKETAPTDDD-WFYTRCASIMRHLYLRSPAGVGAFTKVYSGRKRNGVRPSKHCRSSDGCIRKALQALEAANMVERHPDGGRKLTPQGQRNLDRIANKIVAKQRERSAPVSMIITT-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39018-1", "uniprot_id": "RS19A_DROME", "id": "P39018-1", "name": "Small ribosomal subunit protein eS19A", "aln": "MPGVTVKDIDQHAVTKAVAVFLKKTGKLKVPDQMDIVKTAKFKELAPYDPD-WFYVRCASILRHLYHRSPAGVGSITKIYGGRKRNGVHPSHFCRAADGAARKALQALEHARLVEKHPDGGRKLSSIGQRDLDRIANQIVFKQRDAAKQTGPIVISK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07280-1", "uniprot_id": "RS19A_YEAST", "id": "P07280-1", "name": "Small ribosomal subunit protein eS19A", "aln": "MPGVSVRDVAAQDFINAYASFLQRQGKLEVPGYVDIVKTSSGNEMPPQDAEGWFYKRAASVARHIYMRKQVGVGKLNKLYGGAKSRGVRPYKHIDASGSINRKVLQALEKIGIVEISPKGGRRISENGQRDLDRIAAQTLEEDE-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:*::. : . . * **:: **: ** :* . :* .* * : *** *.** **:* * .*** ..*:*.* : ..* * :. .: . *:.*** * :** .*.:::: ***:*. ", "identical_positions": 44, "similar_positions": 41, "identity": "28.03%" }, { "cls_id": "homologset.agr.SGD:S000005482", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54902-1", "uniprot_id": "NRAM2_RAT", "id": "O54902-1", "name": "Natural resistance-associated macrophage protein 2", "aln": "MVLDPEEKIPDDGASGDHGDSASLG----AINPAYSNSSLPHSTGDSEEPFTTYFD-EKIPIPEEEYS--CFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWVLLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSAGRVPLYGGVLITIADTFVFLFLDKYG------LRKLEAFFGFLIT--IMALTFGYEYVTVKPSQSQVLRGMFVPSCSGCHTPQVEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKQE----VREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNEQVVEVCRNSSSP-HADLFPNDNS-------TLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMS-EFSNGIGWRIAGGILVLLVCSINMYFVVVYVQELGHV-ALYVVAAVVSVAYLGFVFYLGWQCLIALGLSFLDCG---------RSYHLGLTARPEIYLLNTV----DAVSLVSR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49282-1", "uniprot_id": "NRAM2_MOUSE", "id": "P49282-1", "name": "Natural resistance-associated macrophage protein 2", "aln": "MVLDPKEKMPDDGASGDHGDSASLG----AINPAYSNSSLPHSTGDSEEPFTTYFD-EKIPIPEEEYS--CFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWVLLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSAGRVPLWGGVLITIADTFVFLFLDKYG------LRKLEAFFGFLIT--IMALTFGYEYITVKPSQSQVLRGMFVPSCPGCRTPQVEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKQE----VREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNKQVVEVCKNNSSP-HADLFPSDNS-------TLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMS-EFSNGIGWRIAGGILVLIVCSINMYFVVVYVQELGHV-ALYVVAAVVSVAYLTFVFYLGWQCLIALGLSFLDCG---------RSYRLGLTAQPELYLLNTV----DADSVVSR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49281-1", "uniprot_id": "NRAM2_HUMAN", "id": "P49281-1", "name": "Natural resistance-associated macrophage protein 2", "aln": "MVLGPEQKMSDDSVSGDHGESASLG----NINPAYSNPSLSQSPGDSEEYFATYFN-EKISIPEEEYS--CFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIADTFVFLFLDKYG------LRKLEAFFGFLIT--IMALTFGYEYVTVKPSQSQVLKGMFVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQE----VREANKYFFIESCIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSP-HAGLFPKDNS-------TLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMS-DFANGLGWRIAGGILVLIICSINMYFVVVYVRDLGHV-ALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDCG---------HTCHLGLTAQPELYLLNTM----DADSLVSR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41251-1", "uniprot_id": "NRAM1_MOUSE", "id": "P41251-1", "name": "Natural resistance-associated macrophage protein 1", "aln": "--------MISDKSP-PRLSRPSYG----SISSLPG---PAPQPAPCRE---TYLS-EKIPIPSADQG--TFSLRKLWAFTGPGFLMSIAFLDPGNIESDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKDLGEVCHLYYPKVPRILLWLTIELAIVGSDMQEVIGTAISFNLLSAGRIPLWDGVLITIVDTFFFLFLDNYG------LRKLEAFFGLLIT--IMALTFGYEYVVAHPSQGALLKGLVLPTCPGCGQPELLQAVGIVGAIIMPHNIYLHSALVKSREVDRTRRVD----VREANMYFLIEATIALSVSFIINLFVMAVFGQAFYQQTNEEAFNICANSSLQNYAKIFPRDNN-------TVSVDIYQGGVILGCLFGPAALYIWAVGLLAAGQSSTMTGTYAGQFVMEGFLKLRWSRFARVLLTRSCAILPTVLVAVFRDLKDLSGLNDLLNVLQSLLLPFAVLPILTFTSMPAVMQ-EFANGRMSKAITSCIMALVCAINLYFVISYLPSLPHP-AYFGLVALFAIGYLGLTAYLAWTCCIAHGATFLTHS---------SHKHF-------LYGLPNE----EQGGVQGSG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P70553-1", "uniprot_id": "NRAM1_RAT", "id": "P70553-1", "name": "Natural resistance-associated macrophage protein 1", "aln": "--------MIRDKNP-QRVNRPSYG----SISSLPS---PAPQPEPSRN---TYLS-EKIPIPSTEQ-------------------------------------------LLWVLLWATVLGLLCQRLAARLGVVTGKDLGEICHLYYPKVPRILLWLTIELAIVGSDMQEVIGTAISFNLLSAGRIPLWGGVLITIVDTFFFLFLDNYG------LRKLEAFFGFLVT--IMALTFGYEYVVARPSQGALLKGLFLPSCPGCGQPELLQAVGIVGAIIMPHNIYLHSALVKSREVDRTRRGD----VREANMYFLTEATIALFVSFIINLFVMAVFGQAFYQQTNEEAFNICANSSLHNYAKIFPRDNN-------TVSVDIYQGGVILGCLFGPAALYIWAVGLLAAGQSSTMTGTYAGQFVMEGFLKLRWSRFARVLLTRSCAILPTVLVAVFRDLRDLSGLNDLLNVLQSLLLPFAVLPILTFTSMPAVMQ-EFANGWLSKVITSCIMALVCAINLYFVISYLPSLPHP-AYFGLVALLAIGYLGLTAYLAWTCCIAHGAKFLTHS---------SHQRF-------LYGLPIE----EQEGREGSG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49279-1", "uniprot_id": "NRAM1_HUMAN", "id": "P49279-1", "name": "Natural resistance-associated macrophage protein 1", "aln": "--------MTGDKGP-QRLSGSSYG----SISSPTSPTSPGPQQAPPRE---TYLS-EKIPIPDTKPG--TFSLRKLWAFTGPGFLMSIAFLDPGNIESDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKDLGEVCHLYYPKVPRTVLWLTIELAIVGSDMQEVIGTAIAFNLLSAGRIPLWGGVLITIVDTFFFLFLDNYG------LRKLEAFFGLLIT--IMALTFGYEYVVARPEQGALLRGLFLPSCPGCGHPELLQAVGIVGAIIMPHNIYLHSALVKSREIDRARRAD----IREANMYFLIEATIALSVSFIINLFVMAVFGQAFYQKTNQAAFNICANSSLHDYAKIFPMNNA-------TVAVDIYQGGVILGCLFGPAALYIWAIGLLAAGQSSTMTGTYAGQFVMEGFLRLRWSRFARVLLTRSCAILPTVLVAVFRDLRDLSGLNDLLNVLQSLLLPFAVLPILTFTSMPTLMQ-EFANGLLNKVVTSSIMVLVCAINLYFVVSYLPSLPHP-AYFGLAALLAAAYLGLSTYLVWTCCLAHGATFLAHS---------SHHHF-------LYGLLEE----DQKG-ETSG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49283-2", "uniprot_id": "MVL_DROME", "id": "P49283-2", "name": "Protein Malvolio", "aln": "MSSNEAYHEPGAGGDGPGGSSGASGGGSQRSNQLHHQQILNETTYLKPAAKQAYFSDEKVLIPDDDSTNVGFSFRKLWAFTGPGFLMSIAYLDPGNIESDMQSGAAAKYKILWVLLWATVLGLLMQRLAARLGVVTGLHLAEMCYRQYKRLPRWILWIMIEIAIIGSDMQEVIGTAIAIYLLSNKVVPLWGGVLITIVDTFTFLFLDKYG------LRKLEFLFGTLIT--IMAVSFGYEYIVSAPNQGEVLEGMFVPWCSNCNSNVLLQAVGVVGAVIMPHNLYLHSALVKSRDIDRRQTKK----VSEANFYFFIEASVALFVSFIINLFVVAVFAHGMYGKTNNDVVEVCKDKSMYEDAKMSFVDNVNGT---AIIDADLYKGGLFLGCTFGAVAMYIWGVGILAAGQSSTMTGTYAGQFSMEGFLNLQWPRWCRVLVTRCIAIIPTFCLAMFSKMEDLTSMNDILNAVMSLQLPFAAIPTIAFTSCAAIMG-EFVNGLGNKIVSILLTIVVIGVNLYFVVVQVENMEIKGGLLALVCIFAILYILFNLYLVIHMAACMGNQRLMNSRWVQRFVLPSQNSFSIKNANSTYARIATSSDQEPEGLAGEDA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38925-1", "uniprot_id": "SMF1_YEAST", "id": "P38925-1", "name": "Manganese transporter SMF1", "aln": "-MVNVGPSHAAVAVDASEARKRNISEEVFELRDKKDSTVVIEGEAPVRTFTSSSSNHEREDTYVSKRQVMRDIFAKYLKFIGPGLMVSVAYIDPGNYSTAVDAGASNQFSLLCIILLSNFIAIFLQCLCIKLGSVTGLDLSRACREYLPRWLNWTLYFFAECAVIATDIAEVIGTAIALNILIK--VPLPAGVAITVVDVFLIMFTYKPGASSIRFIRIFECFVAVLVVGVCICFAIELAYIPKSTSVKQVFRG-FVPSAQMFDHNGIYTAISILGATVMPHSLFLGSALVQPRLLDYDVKHGNYTVSEEQDKVKKSKSTEEIMEEKYFNYRPTNAAIKYCMKYSMVELSITLFTLALFVNCAILVVAGSTLYNSPEADGADLFTIHELLSRNLAPAAGTIFMLALLLSGQSAGVVCTMSGQIVSEGHINWKLQPWQRRLATRCISIIPCLVISICIGREALSKALNASQVVLSIVLPFLVAPLIFFTCKKSIMKTEITVDHTEEDSHNHQNNNDRSAGSVIEQDGSSGMEIENGKDVKIVYMANNWIITVIAIIVWLFLSLLN---------------------------VYAIVQLG---MSHGDIS---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . *: . :* ::* :..:.:: * *. :** *** .*.. * : . *:: * *::.:*: ****:**:: :* :** ** **:.*.* ::* : * :* :* :.. *:. :..:: *: .. ::.* .:* . : *:.::** :***.::* ****:.* :: * : :: : . :* . . : : . : . .*:: .*. :...* *: :.:* :***: :. * :**: **.:. : : * : **. :*:* . ::: . *: : :.: *: *** * : **. .:* :: . . . . : : . .: :: : . * . ", "identical_positions": 81, "similar_positions": 146, "identity": "13.24%" }, { "cls_id": "homologset.agr.SGD:S000005483", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920Q6-1", "uniprot_id": "MSI2H_MOUSE", "id": "Q920Q6-1", "name": "RNA-binding protein Musashi homolog 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MEANGSPG----------------------------------TSGSANDSQHD------------------------------PGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHR------------------------GFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPPG------------------TRGRARGLPYTMDAFMLGMGML--GYPNFVAT-YG--RGYPGFAPSYGYQFPG-------------------FPAAAYG---------PVAAAAVAAARGSVLNSYSAQPNFGAPAS-------------------------------------------------------------PAGSNPARPGGFPGANSPGPVADLYGPAS----QDSGVGNYISAASPQPGSGFGHGIA------GPLIATAFTNGYH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GG20-1", "uniprot_id": "A0A8I6GG20_RAT", "id": "A0A8I6GG20-1", "name": "RNA-binding protein Musashi homolog 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MEANGSPG----------------------------------TSGSANDSQHD------------------------------PGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHR------------------------GFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPPG------------------TRGRARGLPYTMDAFMLGMGML--GYPNFVAT-YG--RGYPGFAPSYGYQFPALLPYLN-----------ASFPAAAYG---------PVAAAAVAAARGSVLNSYSAQPNFGAPTS-------------------------------------------------------------PAGSNPARPGGFPGANSPGPVADLYGPAS----QDSGVGNYISAASPQPGSGFGHGIA------GPLIATAFTNGYH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96DH6-1", "uniprot_id": "MSI2H_HUMAN", "id": "Q96DH6-1", "name": "RNA-binding protein Musashi homolog 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MEANGSQG----------------------------------TSGSANDSQHD------------------------------PGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHR------------------------GFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPPG------------------TRGRARGLPYTMDAFMLGMGML--GYPNFVAT-YG--RGYPGFAPSYGYQFPG-------------------FPAAAYG---------PVAAAAVAAARG-------------------------------------------------------------------------------SGSNPARPGGFPGANSPGPVADLYGPAS----QDSGVGNYISAASPQPGSGFGHGIA------GPLIATAFTNGYH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GII9-1", "uniprot_id": "A0AC58GII9_DANRE", "id": "A0AC58GII9-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MEADASQV----------------------------------TSGSLNDSQHD------------------------------PGKMFIGGLSWQTSPDSLRDYFCKFGEIRECMVMRDPTTKRSRGFGFITFADVSSVDKVLAQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSASTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRDLRRREELTMTTGFKSNEEVLQKAGFGFVTFENEDIVEKVCEIHFHEINNKMVECKKAQPKEVMFPPG------------------TRGRARSLPYTMDAFMLGMGML--SYPNIVAT-YG--RGYTGFSPSYSYQFPG-------------------FPATAYG---------PVAAAAVAAARGSGRATRGRSGYMAYPQNAGPGFPDYGFYSGPGDQRAAPCSFADYATLGPHTGQMLQSEHVTSTCNSPSQHHPSPDHFKSSGANPPRPGGFPGANSPGPVADLYGPSS----QDSAVGNYISAASPQPGSGFNHSIA------GPLIATAFTNGYH-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B3X4-1", "uniprot_id": "A0A8M2B3X4_DANRE", "id": "A0A8M2B3X4-1", "name": "RNA-binding protein Musashi homolog 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MEGDGSQA----------------------------------TSGSPNDSQHD------------------------------PGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADAASVDKVLAQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHR------------------------GFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPPG------------------TRGRARGLPYTMDAFMLGMGML--SYPNIVAT-YG--RGYTGFAPSYSYQFPG-------------------FPATAYG---------PVAAAAAVAA------ARG------------------------------------------------------------------------SGTNPPRPGAFPGASSPGPVADLYGPTS----QDSGVGNYISAASPQPGSGFGHSIA------GPLIATAFTNGYH-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q61474-1", "uniprot_id": "MSI1H_MOUSE", "id": "Q61474-1", "name": "RNA-binding protein Musashi homolog 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------METDAPQP----------------------------------GLASP-DSPHD------------------------------PCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHR------------------------GFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGS-----------------ARGRSRVMPYGMDAFMLGIGML--GYPGFQATTYAS-RSYTGLAPGYTYQFPEFRVERSPLPSAPVLPELTAIPLTAYG---------PMAAAAAAAAVVRGTGSHPWTMAP------------------------------------------------------------------PPGSTPSRTGGFLGTTSPGPMAELYGAAN----QDSGVSSYISAASPAPSTGFGHSLG------GPLIATAFTNGYH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K3P4-1", "uniprot_id": "MSI1H_RAT", "id": "Q8K3P4-1", "name": "RNA-binding protein Musashi homolog 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------METDAPQP----------------------------------GLASP-DSPHD------------------------------PCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHR------------------------GFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGS-----------------ARGRSRVMPYGMDAFMLGIGML--GYPGFQATTYAS-RSYTGLAPGYTYQFPEFRVERTPLPSAPVLPELTAIPLTAYG---------PMAAAAAAAAVVRGTGSHPWTMAP------------------------------------------------------------------PPGSTPSRTGGFLGTTSPGPMAELYGAAN----QDSGVSSYISAASPAPSTGFGHSLG------GPLIATAFTNGYH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43347-1", "uniprot_id": "MSI1H_HUMAN", "id": "O43347-1", "name": "RNA-binding protein Musashi homolog 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------METDAPQP----------------------------------GLASP-DSPHD------------------------------PCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKQYFEQFGKVDDAMLMFDKTTNRHR------------------------GFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGS-----------------ARGRSRVMPYGMDAFMLGIGML--GYPGFQATTYAS-RSYTGLAPGYTYQFPEFRVERTPLPSAPVLPELTAIPLTAYG---------PMAAAAAAAAVVRGTGSHPWTMAP------------------------------------------------------------------PPGSTPSRTGGFLGTTSPGPMAELYGAAN----QDSGVSSYISAASPAPSTGFGHSLG------GPLIATAFTNGYH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VVE5-1", "uniprot_id": "MSIR6_DROME", "id": "Q9VVE5-1", "name": "RNA-binding protein Musashi homolog Rbp6", "aln": "------------------------------------------------------------------------------------------------------------------------------------MDIKIEQQQQQQQV------------------------------ELGPCSPSEVPND------------------------------PGKMFIGGLSWQTSPESLRDYFGRYGDISEAMVMKDPTTRRSRGFGFVTFSDPNSVDKVLTQGTHELDGKKVDPKVAFPRRAHPKMVTRTKKIFVGGLSAPTTLEDVKSYFEQFGPIEDAMLMFDKQTNRHR------------------------GFGFVTFQSEDVVDKVCEIHFHEINNKMVECKKAQPKEVMLPANL-----------------AKTRAAGR-SAYDNIMWGLGTLPEGFPAAAYAAYAAGRGYSGY-PSFGLPYPTVDLTNGQLTPNNNTPLLTQALSVMNN---------YQAAAAAAHSYGPSASPHA------------------------------------------------------------------------AAANTATRQGFPSTNSPGPTIDMYSSAA----ADN-VG-YVQATSPQP-SGFPIAVSRAPLNYSPIYSLNFAMANI-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IMS8-1", "uniprot_id": "Q8IMS8_DROME", "id": "Q8IMS8-1", "name": "", "aln": "--------MLFENPAVAAKLPFPYNVPPPLQAAAAAAAAVPNLRFQTPIKAFACLTAATRSVSEMNATSLYAGNPMENAAAAAAAAAAGLIDPHHNRDLHQALVASIANNSVAAIGG----------GLTTAAVLKSAAQQSQQAVQQNQNAVVVTPGLEQPKQEPAQQAALALLKENVNASAGAGQNNGQAAMGGSNKSGSSGRSTPSLSGGSGSDPAPGKLFVGGLSWQTSSDKLKEYFNMFGTVTDVLIMKDPVTQRSRGFGFITFQEPCTVEKVLKVPIHTLDGKKIDPKHATPK-NRPRQANKTKKIFVGGVSQDTSAEEVKAYFSQFGPVEETVMLMDQQTKRHR------------------------GFGFVTFENEDVVDRVCEIHFHTIKNKKVECKKAQPKEAVTPAAQLLQKRIMLGTLGVQLPTAPGQLIGARGAGVATMNPLAMLQNPTQLLQSPAAAAAAQQAALISQNPFQVQNAAAAASIANQAGFGKLLTTYPQTALHSVRYAPYSIPASAATANAALMQAHQAQSVAAAAHHHQQQQQQQHHHQQQTHNAHVAAAQQQQQSHHN----------------AVSNPASQAHSAAAAAALAANAANGAGAAGAHSLAAAAQQAGLMAGNPLNAAAAAAAAAANPAAAYSNYALANVDMSSFQGVDWSTMYGMGMYV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08473-1", "uniprot_id": "SQD_DROME", "id": "Q08473-1", "name": "RNA-binding protein squid", "aln": "---------------------------------------------------------------MAENKQVDTEINGED--------------------FTKDVTADGPGSENGDAG--------------------AAGSTNGSSD--------------------------------NQSAASGQRDD------------------------------DRKLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTEAIDKVSAADEHIINSKKVDPKKAKARHG---------KIFVGGLTTEISDEEIKTYFGQFGNIVEVEMPFDKQKSQRK------------------------GFCFITFDSEQVVTDLLKTPKQKIAGKEVDVKRATPKPENQMMGGMRGG-------------PRGGMRGGRGGYGGRGGYNNQWDGQGSYGGYGGGYGGYGAGGYGDYYAGGYYNGYDYG-------------------------------------------------------------------------------------------------------------------------YDGYGYGGGFEGNGYGGGGGGNMGGGRGGPRGGGGPKGGGGFNGGKQRGGGGR-----------QQRHQPY------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99020-1", "uniprot_id": "ROAA_MOUSE", "id": "Q99020-1", "name": "Heterogeneous nuclear ribonucleoprotein A/B", "aln": "------------------------------------------------------------MSDAAEEQPMETTGATENGHEAAPEG---------EAPVEPSAAAAAPAASAGSGGG---------------TTTAPSGNQNGAEG--------------------------------DQINASKNEED------------------------------AGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDSSSVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVK-----KIFVGGLNPEATEEKIREYFGQFGEIEAIELPIDPKLNKRR------------------------GFVFITFKEEDPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YGSGGRGNRNRGN---RGSGG--GQGSTNYGKSQRRGGH-----------QNNYKPY------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99383-1", "uniprot_id": "HRP1_YEAST", "id": "Q99383-1", "name": "Nuclear polyadenylated RNA-binding protein 4", "aln": "MSSDEEDFNDIYGDDKPTTTEEVKKEEEQNKAGSGTSQLDQLAALQALSSSLNKLNNPNSNNSSSNNSNQDTSSSKQDGTANDKEGSNEDTKNEKKQESATSANANANASSAGPSGLPWEQLQQTMSQFQQPSSQSPPQQQVTQTK--------------------------------EERSKADLSKE------------------------------SCKMFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPATGRSRGFGFLSFEKPSSVDEVVKT-QHILDGKVIDPKRAIPRDEQDKTG----KIFVGGIGPDVRPKEFEEFFSQWGTIIDAQLMLDKDTGQSR------------------------GFGFVTYDSADAVDRVCQNKFIDFKDRKIEIKRAEPRHMQQKSSNNGGN-------------NGGNNMNRRGGNFGNQGDFNQMYQNPMMGGYNPMMNPQAMTDYYQKMQEYYQQMQKQTGMDYTQMYQQQMQQMAMMMPGFAMPPNAMTLNQPQQDSNATQGSPAPSDSDNNKSNDVQTIGN----------------------------------------------TSNTDSGSPPLNLPNGPKGPSQYNDDHNSGYGYNRDRGDRDRNDRDRDYNHRSGGNHRRNGRGGRGGYNR-----RNNGYHPYNR----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: *:*:***.*:*: . *:::* :* : . : ** * *****.*: * . :::* * ::.: :*** * . ******: :... :* *:* : : :* : : ** *:*:.. : * : : . . : * * *: . . : . : ", "identical_positions": 44, "similar_positions": 56, "identity": "6.35%" }, { "cls_id": "homologset.agr.SGD:S000005484", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TNK6-1", "uniprot_id": "TRM11_RAT", "id": "Q7TNK6-1", "name": "tRNA (guanine(10)-N(2))-methyltransferase TRMT11", "aln": "MALPG--SLNRYLLLMAQEHLEFRLPEIKSLLSVIGGQFTNSQETYGKSPFWILNIPSEDIARNLMKRTVCAKSLFELWGHGKSPEELYSSLKSYP-VEKMVPFLHSDSTYKIKIHTFNKTLTQEEKVKRIDALEFLPFEGKVNLKKPQHVFSILEDYG-LDPNCIPENPHNIYFGRWIADGQRELIESYSVKKRHFIGNTSMDAGLSFIMANHAKVKENDLVFDPFVGTGGLLIASAHFGAYVCGTDIDYNTVHGLGKASRKNQKWRGPDENIRANLRQYGLEKFYLDVLVSDASKPSWRKGTYFDAIITDPPYGIRESTRRTGSQ-------KEILKGIEK---CPESHVPVSLTYHLSDMFLDLINFAAETLVLGGRLVYWLPVYTPEYTEKMVPWHPCLRLVSNCEQKLSSHTARRLITMEKVKEFENPDEYSRLLSDHFLPYQGHNSFREKYFSGVTKRIATEEQCSHEGKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWH5-1", "uniprot_id": "TRM11_MOUSE", "id": "Q9CWH5-1", "name": "tRNA (guanine(10)-N(2))-methyltransferase TRMT11", "aln": "MALPG--SLNRYLLLMAQEHLEFRLPEIKSLLSVIGGQFTNSQETYGKSPFWILNIPSEDIARNLMKRTVCAKSIFELWGHGKSPEELYTSLKSYP-VEKMVPYLHSDSTYKIKIHTFNKTLTQEEKVKRIDALEFLPFQGKVNLKKPQHVFSILEDYG-LDPNSIPKDPHNIYFGRWIADGQRELIESYSVKKRHFIGNTSMDAGLSFIMTNHAKVKENDLVFDPFVGTGGLLIASAHFGAYVCGTDIDYNTVHGLGKASRKNQKWRGPDENIRANLRQYGLEKFYLDVLVSDASKPSWRKGTYFDAIITDPPYGIRESTRRSGSQ-------KDIPKGIEK---CPESHVPVSLSYHLSDMFFDLLNFAAETLVLGGRLVYWLPVYTPEYTEEMVPWHPCLRLISNCEQKLSSHTARRLITMEKVKEFENRDKYSHLLSDHFLPYQGHNSFREKYFSGVTKRIAKEEKCSHE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z4G4-1", "uniprot_id": "TRM11_HUMAN", "id": "Q7Z4G4-1", "name": "tRNA (guanine(10)-N(2))-methyltransferase TRMT11", "aln": "MALSC--TLNRYLLLMAQEHLEFRLPEIKSLLLLFGGQFASSQETYGKSPFWILSIPSEDIARNLMKRTVCAKSIFELWGHGQSPEELYSSLKNYP-VEKMVPFLHSDSTYKIKIHTFNKTLTQEEKIKRIDALEFLPFEGKVNLKKPQHVFSVLEDYG-LDPNCIPENPHNIYFGRWIADGQRELIESYSVKKRHFIGNTSMDAGLSFIMANHGKVKENDIVFDPFVGTGGLLIACAHFGAYVYGTDIDYNTVHGLGKATRKNQKWRGPDENIRANLRQYGLEKYYLDVLVSDASKPSWRKGTYFDAIITDPPYGIRESTRRTGSQ-------KEIPKGIEKWEKCPESHVPVSLSYHLSDMFLDLLNFAAETLVLGGRLVYWLPVYTPEYTEEMVPWHPCLELVSNCEQKLSSHTSRRLITMEKVKKFENRDQYSHLLSDHFLPYQGHNSFREKYFSGVTKRIAKEEKSTQE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PGS2-1", "uniprot_id": "A0A8M1PGS2_DANRE", "id": "A0A8M1PGS2-1", "name": "tRNA (guanine(10)-N(2))-methyltransferase TRMT11", "aln": "MALHCGRACRQYLLHLAHDNVDFRLAEIKALLSLRDRPFETPETFKEKSPFWHLNGLSEDDIRSVMSRTVCGKSAFELWGHGKTTEELRRSLLEYP-SENMAPYLQQNSTYKINVYTFNKTLEFKDRIKKIDALDFLPFEGTVNLKDPEHIFCLLEDYG-TDPNDIPEEPVYVYFGRWIADGQRELIRSYSVKKRHFIGNTSMDAGLSFIMANHAKVKANDLVYDPFVGTGSLLVACSHFGAYVCGTDIDYNTIHGIGKASRKNQKWRGPDENIRANLRQYGAENLYVDVMVSDASKLVWRRNAQFDAIITDPPYGIRESTRRTGSH-------KDIIKPPED--FSGESHVPVSMAYHLSDIFADLLNFAAHHLVLGGRLVYWLPIYRPEYCEEMVPLHPCLTLISNCEQTLSSHTSRRLITMEKTKDPEDSDSLAHLADPRFTPYHGHNSFREKYFSGLTKKNGKNAKVTAENED", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12463-1", "uniprot_id": "TRM11_YEAST", "id": "Q12463-1", "name": "tRNA (guanine(10)-N(2))-methyltransferase", "aln": "--------MKKYLLYMVQVHLNFRRAELESLADLYNLSIDFS-QYDANSPFFIVELENDQQAKDWIKRSILTRGIYEYWGQGTTLDELHKDIQRQSNFEQDLQLKFKHSTFKFEFECYKGNSK-AKRVEQIETFRYLGFEGKIDMKHPQEVFTVIEEYTPISENVGGKTPTRIYFGRQVQMSNRSAMEKYDLKKRPYKGTTSFEAELSLVSANIAQVKPGTIMYDPFAGTGSFLVAGGHFGSLVIGSDIDGRMIRGK-----------GAQVNISANFKKYGESSQFLDVLTMDFTNNALRNNLVIDTILCDPPYGIRESIKVLGAKDPERFLGKEDMEIDGEKAYLRRDYIPTKKPYALDSLLDDLLQYSSERLPIGGRLAFWMPTANDANIETIVPMHENLELKYNCVQEFNKWSRRLLVYINRGSTFNGSSNHG--------IKRSKDNFRERYFNNFN---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:*** :.: :::** .*:::* : . : . :***: :. .:: :. :.*:: :. :* **:* : :** .: . *: ..**:*::. :: . .::::*::: :* *:*.:::*.*:.:* ::*:* . * : * :**** : .:*. :..*.:*** : *.**::* **:: :* .:** . :::***.***.:*:* .***: * *:*** . ::* *.: ** **:::** .. ::**:. * :: *.. :*:*: ********* : *:: *: : . ..::*.. .* *..:: **:::::. * :****.:*:* * :** * * * ** * :.. : * *: ::: . :. .. . :.::.***:**.... ", "identical_positions": 119, "similar_positions": 174, "identity": "24.95%" }, { "cls_id": "homologset.agr.SGD:S000005485", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BYH3-1", "uniprot_id": "TRM13_MOUSE", "id": "Q8BYH3-1", "name": "tRNA:m(4)X modification enzyme TRM13 homolog", "aln": "--MEAPAATSPSIGFPIDGRCNYFVEKKKRFCRMVAAAGKRFCGEHA--------------GSAEEENTRKRILCPLDPKHTVYEDQLAKHLKKCNSREKPKPDFFIQDINAGLKDETEIPEQLVPFSSLSEEQLENLIKKLRKASEGLNSTHEDHIMSHPALHDALNDPRNGDCAVKHLKQQASILGNIEKLKLLGPRR--CFVEFGAGKGKLSHWVDIALK-----------DAENVHFILVERVTTRFKVDGKHRKKD--------------SVFERLQIDIQHLCLNRVPVLREGR-LPVVGIGKHLCGVATDVALRCLVETYAASFEEKDEEPLAKRIKNDKTEKESNTLAKEGSEKDVPETWTPVAGIVIALCCHHRCDWRHYVGKEYFKALGLGAVEFYYFQRMSSWATCGMR-TSLEGSDVTPERKDAQRDENEEHDDGGDRLTDGNTDSLPGILTVEEKKKIGHLCKLLIDQGRLQYLQQKG--FSPALQYYTDPLVSLENVLLTAVPAHPSSQEKHHQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NUP7-1", "uniprot_id": "TRM13_HUMAN", "id": "Q9NUP7-1", "name": "tRNA:m(4)X modification enzyme TRM13 homolog", "aln": "--MATSATSPHAPGFPAEGRCGYYVEKKKRFCRMVVAAGKRFCGEHA--------------GAAEEEDARKRILCPLDPKHTVYEDQLAKHLKKCNSREKPKPDFYIQDINAGLRDETEIPEQLVPISSLSEEQLEKLIKKLRKASEGLNSTLKDHIMSHPALHDALNDPKNGDSATKHLKQQASILGNIENLKLLGPRR--CFVEFGAGKGKLSHWVDIALK-----------DAEKVHFILVEKVTTRFKVDGKHRKKN--------------SVFERLQIDIQHLCLNKIPVLREEK-LPVVGIGKHLCGMATDLALRCLVETYAASFEERNEEPLAKRIKNDKTEKEIYTLAKEGNEKNVPEKWNPVAGIVIALCCHHRCDWRHYVGKEYFRALGLGAVEFHYFQRMSSWATCGMRKTSLETSNSTTKRQDNQNDDSEEHDDGGYRITDDGADCLPGLLSVEEKKKIGHLCKLLIDQGRIQYLQQKG--FSPALQYYTDPLVSLENVLLTALPNHSSSPETTA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12383-1", "uniprot_id": "TRM13_YEAST", "id": "Q12383-1", "name": "tRNA:m(4)X modification enzyme TRM13", "aln": "MLQDNNGPAVKRAKPSERLQCEYFMEKKKRRCGMTRSSQNLYCSEHLNLMKKAANSQVHNKNGSEAEKERERVPCPLDPNHTVWADQLKKHLKKCNKTKLSHLNDDKPYYEPGYNGENGLLSSSVKID-ITAEHLVQSIELLYKVFEGESMDELPLRQLNNKLMSLKRFPQLP-SNTKHAVQQSSLIENLVDAGAFERPESLNFIEFGCGRAEFSRYVSLYLLTQLTSLPAEHSGSNSNEFVLIDRATNRMKFDKKIKDDFSEIKSNSPSKPISCPSIKRIKIDIRDLKMDPILKSTPGDDIQYVCISKHLCGVATDLTLRCIGNSSILHGDDNNG------------------------------CNPKLKAICIAMCCRHVCDYGDYVNRSYVTSLVEKYRAHGSILTYETFFRVLTKLCSWGTCGRKPGTAITDIVNVVESFEG----------AEPYTITIKERENIGLMARRVIDEGRLVYVKEKFTEFNAELIRYVESDVSLENVAMLVYKK----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: . :* *::***** * *. :: : :*.** ..:* *. *:*: *****:***: *** *******. : .: : :.* ..*. : .. * :. :: *:* : *: * *. ** . : * . . *: . .** **:*:: *: . : . *:***.*:.::*::*.: * .::. .*:*:::.*.*:*.* * :.. . ::*::***:.* :: : : * *.*****:***::***: :: ::.: : .* **:**:* **: .**.:.*. :* . : .:: : * .. .. : : * :* . * ::::*:::** :.: :**:**: *:::* *.. * *.:. ****** : . ", "identical_positions": 119, "similar_positions": 152, "identity": "22.54%" }, { "cls_id": "homologset.agr.SGD:S000005486", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04636-1", "uniprot_id": "MDHM_RAT", "id": "P04636-1", "name": "Malate dehydrogenase, mitochondrial", "aln": "--MLSALARPVGAALRRSFSTSAQNN-AKVAVLGASGGIGQPLSLLLKNSPLVSR-----------LTLYDIAHTP--GVAADLSHIETRANVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHC--PEAMICIISNPVNSTIPITAEVFKKHGVYNPN-----KIFGVTTLDIVRANTFVAEL---KGLDPAR---VNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLATLTGRIQEAGTEVVKAKAGAGSATLSMAYAG----ARFVFSLVDAMNGKEG--VIECSFVQ------------SKETECTYFSTPLLLGKKGLEKNLG--IGKITPFEE-KMIAEAIPELKASIKKGEDFVKNMK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08249-1", "uniprot_id": "MDHM_MOUSE", "id": "P08249-1", "name": "Malate dehydrogenase, mitochondrial", "aln": "--MLSALARPAGAALRRSFSTSAQNN-AKVAVLGASGGIGQPLSLLLKNSPLVSR-----------LTLYDIAHTP--GVAADLSHIETRANVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHC--PEAMVCIIANPVNSTIPITAEVFKKHGVYNPN-----KIFGVTTLDIVRANTFVAEL---KGLDPAR---VNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLATLTGRIQEAGTEVVKAKAGAGSATLSMAYAG----ARFVFSLVDAMNGKEG--VVECSFVQ------------SKETECTYFSTPLLLGKKGLEKNLG--IGKITPFEE-KMIAEAIPELKASIKKGEDFVKNMK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40926-1", "uniprot_id": "MDHM_HUMAN", "id": "P40926-1", "name": "Malate dehydrogenase, mitochondrial", "aln": "--MLSALARPASAALRRSFSTSAQNN-AKVAVLGASGGIGQPLSLLLKNSPLVSR-----------LTLYDIAHTP--GVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHC--PEAMICVIANPVNSTIPITAEVFKKHGVYNPN-----KIFGVTTLDIVRANTFVAEL---KGLDPAR---VNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAG----ARFVFSLVDAMNGKEG--VVECSFVK------------SQETECTYFSTPLLLGKKGIEKNLG--IGKVSSFEE-KMISDAIPELKASIKKGEDFVKTLK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VEB1-1", "uniprot_id": "Q9VEB1_DROME", "id": "Q9VEB1-1", "name": "Malate dehydrogenase, mitochondrial", "aln": "--MLKQVTKQLALQGVRTFSVGQQNN-YKVTVCGAAGGIGQPLSLLLKQNPLVTD-----------LALYDIVHTP--GVAADLSHIDTKSKTAGFIGADQLGDSLKGSDVVVIPAGVPRKPGMTRDDLFNVNAGIIKDISNSIAKNC--PKALVAIITNPVNTCVPIAAEILKKAGVYDPK-----RLFGVSTLDVVRARAFIGHA---LGVDPQT---VQIPVIGGHSGVTILPVLSQSQPLFKGNQDTIEKLTVRIQEAGTEVVKAKAGAGSATLSMAYAG----ARFAGSLLKGLNGEKN--VIECSYVQ------------STVTEATFFSTPLVLGKNGVQENLG--LPKLNDYEK-KLLEAAIPELKKNIQKGIDFANA------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VU29-1", "uniprot_id": "Q9VU29_DROME", "id": "Q9VU29-1", "name": "Malate dehydrogenase", "aln": "MFLASRLLSHVGNLPPKVQQLGYINRGLKVAVVGSVGGIGQPLSLLLKHNPQIST-----------LSLYDIKNTT--GVGVDLSHINTRASVCPFEGKNGLKKAMDKADIVVIPAGLPRKPGMKREDLVDVNASVACEVAFAASEVC--PGAMLAFITNPINVIVPIVATILKAKGTYDPN-----RLFGVTTLDVVRAQTFVADI---LNVDPQK---VNIPVIGGHTGRTILPILSQCDPPFKGTDKEREALIQRIQNAGTEVVNAKDGLGSATLSMAFAA----TQFVSSLIKGIKGSKDECIVECAYVE------------SDVTEAQFFATPLILGPQGVKENTG--LPDLDDEER-KALNGMLPILKESIAKGIKLGEGMICSCA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22133-1", "uniprot_id": "MDHC_YEAST", "id": "P22133-1", "name": "Malate dehydrogenase, cytoplasmic", "aln": "--------------MPHSVTPSIEQDSLKIAILGAAGGIGQSLSLLLKAQLQYQLKESNRSVTHIHLALYDVNQEAINGVTADLSHIDTPISVSSHSPAGGIENCLHNASIVVIPAGVPRKPGMTRDDLFNVNAGIISQLGDSIAECCDLSKVFVLVISNPVNSLVPVMVSNILKNHPQSRNSGIERRIMGVTKLDIVRASTFLREINIESGLTPRVNSMPDVPVIGGHSGETIIPLFSQSNFLSRLNEDQLKYLIHRVQYGGDEVVKAKNGKGSATLSMAHAGYKCVVQFVSLLLGNIEQIHGTYYVPLKDANNFPIAPGADQLLPLVDGADYFAIPLTITTKGVSYVDYDIVNRMNDMERNQMLPICVSQLKKNIDKGLEFVASRSASS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : *::: *: *****.****** . *:***: : . ** .*****:* . . : ..:. ..:******:******.*:**.:.** : : : :: * . .:: .*:**:* :*: . : . : :::**:.**:*** :*: . .: * ::******:* **:*::**. :. * *:* .* ***:** * ********.*. .:*. *: :: .. : .: . . :*: ** : :*:. : : *. : : :. ** .* ** .: ", "identical_positions": 100, "similar_positions": 103, "identity": "25.51%" }, { "cls_id": "homologset.agr.SGD:S000005487", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LT35-1", "uniprot_id": "F1LT35_RAT", "id": "F1LT35-1", "name": "Large ribosomal subunit protein uL23", "aln": "----------------------------------MLGIFQLWRLKQDGHLKPKAKKEAPAPPK-----------------AEAKAKALKAKKAVLKG-------------------------------------------------------VHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62751-1", "uniprot_id": "RL23A_MOUSE", "id": "P62751-1", "name": "Large ribosomal subunit protein uL23", "aln": "-------------------------------------------------MAPKAKKEAPAPPK-----------------AEAKAKALKAKKAVLKG-------------------------------------------------------VHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62750-1", "uniprot_id": "RL23A_HUMAN", "id": "P62750-1", "name": "Large ribosomal subunit protein uL23", "aln": "-------------------------------------------------MAPKAKKEAPAPPK-----------------AEAKAKALKAKKAVLKG-------------------------------------------------------VHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62752-1", "uniprot_id": "RL23A_RAT", "id": "P62752-1", "name": "Large ribosomal subunit protein uL23", "aln": "-------------------------------------------------MAPKAKKEAPAPPK-----------------AEAKAKALKAKKAVLKG-------------------------------------------------------VHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W0A8-1", "uniprot_id": "Q9W0A8_DROME", "id": "Q9W0A8-1", "name": "", "aln": "MPPKKPTEKSAKPGDKKPEQKKTAAAPAAGKKEAAPSAAKPAAAAPKKAAAPAAKKAAPAAKKPATAGAAAKKPAAVKTTAAAKAKSKDAKKKVLAGKKPQSVLAKLSAKARAAAKAKKGVKPVTKPAKGTAKAKAVALLNAKKVQKKIIKGAFGTRARKIRTNVHFRRPTTLKLPRSPKYPRKSVPTRNRMDAYNIIKYPLTTEAAMKKIEDNNTLVFLTHLRANKNHVRAAVRKLYDIKVAKVNVLIRPDGQKKAYVRLARDYDALDIANKIGII", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04456-1", "uniprot_id": "RL25_YEAST", "id": "P04456-1", "name": "Large ribosomal subunit protein uL23", "aln": "-------------------------------------------------MAPSAKATA-------------------------------AKKAVVKG-------------------------------------------------------TNGKKALKVRTSATFRLPKTLKLARAPKYASKAVPHYNRLDSYKVIEQPITSETAMKKVEDGNILVFQVSMKANKYQIKKAVKELYEVDVLKVNTLVRPNGTKKAYVRLTADYDALDIANRIGYI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ** * *** *: * . . : *:**. ** *.**:* * ***. *:.* *::* * :*: *:*:*:****:**.* *** . ::*** ::: **::**::.* ***.*:**:* *******: ******:**:** *", "identical_positions": 74, "similar_positions": 37, "identity": "26.71%" }, { "cls_id": "homologset.agr.SGD:S000005488", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O76039-2", "uniprot_id": "CDKL5_HUMAN", "id": "O76039-2", "name": "Cyclin-dependent kinase-like 5", "aln": "-MKIPNIG----NVMNKFEILG-----------------------VVGEGAYG----VVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLY---LVFEYVEKNMLELLEEMPNG---VPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHN-DVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAP-YGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRLLDRSPSRSAKRKPYHVESSTLSNRNQAGKSTALQSHHRSNSKDIQNLSVGLPRADEGLPANESFLNGNLAGASLSPLHTKTYQASSQPGSTSKDLTNNNIPHLLSPKEAKSKTEFDFNIDPKPSEGPGTKYLKSNSRSQQNRHSFMESSQSKAGTLQPNEKQSRHSYIDTIPQSSRSPSYRTKAKSHGALSDSKSVSNLSEARAQIAEPSTSRYFPSSCLDLNSPTSPTPTRHSDTRTLLSPSGRNNRNEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTSPFSSQQRPHRHSMYVTRDKVRAKGLDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVARSSVKETSREGTSSFHTRQKSEGGVYHDPHSDDGTAPKENRHLYNDPVPRRVGSFYRVPSPRPDNSFHENNVSTRVSSLPSESSSGTNHSKRQPAFDPWKSPENISHSEQLKEKEKQGFFRSMKKKKKKSQTVPNSDSPDLLTLQKSIHSASTPSSRPKEWRPEKISDLQTQSQPLKSLRKLLHLSSASNHPASSDPRFQPLTAQQTKNSFSEIRIHPLSQASGGSSNIRQEPAPKGRPALQLPGQMDPGWHVSSVTRSATEGPSYSEQLGAKSGPNGHPYNRTNRSRMPNLNDLKETAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LCR6-1", "uniprot_id": "A0ABK0LCR6_RAT", "id": "A0ABK0LCR6-1", "name": "Cyclin-dependent kinase-like 5", "aln": "-MKIPNIG----NVMNKFEILG-----------------------VVGEGAYG----VVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLY---LVFEYVEKNMLELLEEMPNG---VPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHN-DVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAP-YGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRLLDRSPSRSTKRKPYHVESSTLSNRSQSTKGGALQTHHRSNSKDIQNLSVGLPRAEEGLPANESFLNGNLAGATLSPMHTKTYQASTQPGSSSKDLTNNNIPHLLSPKEAKSKTEFDFNIDPKPSEGPGTKYLKSSTRSQQNRHSFMESSQSKAGTLQPSEKQSRHSYIDTIPQSSRSPSYRTKAKSHGALSDSKSVSNLSEARAQITETNTSRYFPSSCLDLNSPTSPTPTRHTDTRTLLSPSGRNNRNEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTSPFSSQQRPHRHSMYVTRDKVRAKGIDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVARPSVKESSREGTSSFHTRQKSEGGVYHDPHSDDGTAPKENRHLYNDPVPRRVGSFYRVPSPRPDNSFHENNVSTRVSSLPSDSSSGTNHSKRQPGFDPWKSPENISHSDQLKEKEKQGFFRSMKKKKKKTQTVPNTDGPDLLTLQKAIHSSSTASSRPKEWRPEKLSDLQTQSQPLKSLRKLLHLSSSTNHPASSDPRFQPLTAQQAKNSFSEIRIHPLSQASGGSSNIRQEPTPKGRPALQLPGQMDPGWHVSSVTRSATEGPSYSEQLGAKSGPNGHPYNRTNRSRMPNLNDLKETAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UTQ8-1", "uniprot_id": "CDKL5_MOUSE", "id": "Q3UTQ8-1", "name": "Cyclin-dependent kinase-like 5", "aln": "-MKIPNIG----NVMNKFEILG-----------------------VVGEGAYG----VVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLY---LVFEYVEKNMLELLEEMPNG---VPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHN-DVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAP-YGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRLLDRSPSRSTKRKPYHVESSTLSNRNQSTKGAALQTHHRSNSKDIQNLSVGLPRAEEGLPANESFLNGNLAGATLSPMHTKTYQASTQPGSSSKDLTNNNIPHLLSPKEAKSKTEFDFNIDTKPSEGPGTKYLKSSTRSQQNRHSFMESSQSKAGTLQPSEKQSRHSYIDTIPQSSRSPSYRTKAKSHGALSDSKSVSNLSEARAQITETNTSRYFPSSCLDLNSPTSPTPTRHTDTRTLLSPSGRNNRNEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTSPFSSQQRPHRHSMYVTRDKVRAKGLDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVARPSVKESSREGASSFHTRQKSEGGVYHDPHSDDGTAPKENRHLYNDPVPRRVGSFYRVPSPRPDNSFHENNVSTRVSSLPSDSSSGTNHSKRQPGFDPWKSPENISHADQLKEKEKQGFFRSMKKKKKKTQTVPNTDGPDLLTLQKAIHSSSTASSRPKEWRPEKLSDLQTQSQPLKSLRKLLHLSSSTNHPASSDPRFQPLTAQQAKNSFSEIRIHPLSQATGGSSNIRQEPTPKGRPALQLPGSSLLRYNGWKHSRSRSSQPDEVIFLASHEKWKQ----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12222-1", "uniprot_id": "YGK3_YEAST", "id": "Q12222-1", "name": "Glycogen synthase kinase-3 homolog YGK3", "aln": "MLKVNNVFGSNPNRMTKLEDEHYFIDDIVSIKNRQKSKMYVREGKRIGHGSFGTVTQSILSSNSIEWLGPYAIKRVVKSPKVQSLELEILQNIRHPNLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDD--NTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEEIAKLLGRFPKSSIKNSQE------LQDSLNDQKFKKFMHWFPSIEFFDVEFLLKVLTYDATERCDARQLMAHEFFDALRNETYFLPRGS------------------------------------SMPVHLP-----------------------------------------DLFN----------------------------------------------------------FSASEKRALGEYYNLIVPSLD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: *: * *.*:* :*.*::* :*... * ***:. .* : :.:: *:::: . :. * :.* : : : *:** :*:**: :.: . :.* :. :*.:::* * :*:::*: *. .* * *:**.*:** . .: *:**** *:.*.: *:: . *..:*:**:*****.: * ..:*:**:***:**: .***** *:* .** * *:** :*...:* . *: . :: . ::: :: . :::: ::*. *.::* :.* : * *:: * .*.: .:.* ** ** * :...**:: .* : * * ", "identical_positions": 100, "similar_positions": 135, "identity": "10.0%" }, { "cls_id": "homologset.agr.SGD:S000005489", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8J8XSG2-1", "uniprot_id": "A0A8J8XSG2_RAT", "id": "A0A8J8XSG2-1", "name": "", "aln": "MRTDWGGVGWAGPAHPHPGVWLPVAVLFSCRTGVNRGCQTRRDIGLGQGSRC---SECMDWGEKRNTVASIAAGVLFFTGWWIIIDAAVMYPNMEQFNHSYHACG----VIATIAFLMINAVSNGQVRG--DSYSEGCLGQTG----------ARIWLFIGFMLAFGSLIASMWILFGGYVAKEKAI---VYPGIAVFFQNAFIFFGGLVFKFGR-TEDLWQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CXL1-1", "uniprot_id": "TM50A_MOUSE", "id": "Q9CXL1-1", "name": "Transmembrane protein 50A", "aln": "------------------------------------------MSGFLEGSRC---SECMDWGEKRNTIASIAAGVLFFTGWWIIIDAAVMYPRMDQFNHSYHTCG----VIATIAFLMINAVSNGQVRG--DSYSEGCLGQTG----------ARIWLFIGFMLAFGSLIASMWILFGGYVAKEKDV---VYPGIAVFFQNAFIFFGGLVFKFGR-TEDLWQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95807-1", "uniprot_id": "TM50A_HUMAN", "id": "O95807-1", "name": "Transmembrane protein 50A", "aln": "------------------------------------------MSGFLEGLRC---SECIDWGEKRNTIASIAAGVLFFTGWWIIIDAAVIYPTMKDFNHSYHACG----VIATIAFLMINAVSNGQVRG--DSYSEGCLGQTG----------ARIWLFVGFMLAFGSLIASMWILFGGYVAKEKDI---VYPGIAVFFQNAFIFFGGLVFKFGR-TEDLWQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D1X9-1", "uniprot_id": "TM50B_MOUSE", "id": "Q9D1X9-1", "name": "Transmembrane protein 50B", "aln": "------------------------------------------MAGFLDNFRWP-ECECIDWSERRNTVASVVAGILFFTGWWIMIDAAVVYPKPEQLNHAFHTCG----VFSTLAFFMINAVSNAQVRG--DSYESGCLGRTG----------ARVWLFIGFMLMFGSLIASMWILFGAYVTQNID----VYPGLAVFFQNALIFFSTLIYKFGR-TEELWA-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56557-1", "uniprot_id": "TM50B_HUMAN", "id": "P56557-1", "name": "Transmembrane protein 50B", "aln": "------------------------------------------MAGFLDNFRWP-ECECIDWSERRNAVASVVAGILFFTGWWIMIDAAVVYPKPEQLNHAFHTCG----VFSTLAFFMINAVSNAQVRG--DSYESGCLGRTG----------ARVWLFIGFMLMFGSLIASMWILFGAYVTQNTD----VYPGLAVFFQNALIFFSTLIYKFGR-TEELWT-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZE2-1", "uniprot_id": "Q9VZE2_DROME", "id": "Q9VZE2-1", "name": "Transmembrane protein 50A", "aln": "-------------------------------------------MGVLDNIAL-----HFTGDASRNRNTSIIAGLLFFAGWWVLIDAMSIDGK-HQITTGHVFIG----IFGTISFCMVNAVKGEHISD--ENSSE--SGARI----------AKIWLLVGFLMGFASIIAAIWVMIDDFINNEKKD---GWFGVALLMQNVFILFASLVYKFGR-NEEEWNE----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12016-1", "uniprot_id": "VPS68_YEAST", "id": "Q12016-1", "name": "Vacuolar protein sorting-associated protein 68", "aln": "-------------------------------------------MEADDHVSLFRFPFKIPTFRGIRKGGVYLSGALYALGFWIFLDAVLYSRYSNASDVHVTFIDWIPFLCSTLGTLIVNSIEKNRLLQGALSSDGGAFGSGVGDLDSSMAWQARTVLFFGFALLAGGLSGSIVVLIIKFLVKDYNTYPTLGMGVNNVLGNVCILLSCVVLWIAQNVEDEYSYSLTL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . :* *: *:*:::** . . : .*:. ::*::. :: . . * *: *:.** : ..: .:: ::: :: :: *: .: *. *::. :: :.: *: : ", "identical_positions": 17, "similar_positions": 55, "identity": "7.49%" }, { "cls_id": "homologset.agr.SGD:S000005493", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62878-1", "uniprot_id": "RBX1_MOUSE", "id": "P62878-1", "name": "E3 ubiquitin-protein ligase RBX1", "aln": "MAAAMD-VDTPS----------GTNSG----AGKKRFEVK--KWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62877-1", "uniprot_id": "RBX1_HUMAN", "id": "P62877-1", "name": "E3 ubiquitin-protein ligase RBX1", "aln": "MAAAMD-VDTPS----------GTNSG----AGKKRFEVK--KWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JUC8-1", "uniprot_id": "A0A0G2JUC8_RAT", "id": "A0A0G2JUC8-1", "name": "E3 ubiquitin-protein ligase RBX1", "aln": "MARELV-TEAAA----------EILTSLLCYPENALFPLFSLQWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W5E1-1", "uniprot_id": "RBX1A_DROME", "id": "Q9W5E1-1", "name": "RING-box protein 1A", "aln": "MEVDEDGYEVPS----------SSSKG-----DKKRFEVK--KWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWDFQKYGH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9NHX0-1", "uniprot_id": "RBX1B_DROME", "id": "Q9NHX0-1", "name": "RING-box protein 1B", "aln": "MAEEIEVEETEDFHDMDFNDEEPSCSGGAVQARTERFVVK--KWVAHAMWGWDVAVDNCAICRNHIMNLCIECQADPN-ANQDECTVAWGECNHAFHYHCIARWLKTRLVCPLDNKEWVYQKYGR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08273-1", "uniprot_id": "RBX1_YEAST", "id": "Q08273-1", "name": "RING-box protein HRT1", "aln": "MSNEVDRMDVDE--DESQNIAQSSNQSAPVETKKKRFEIK--KWTAVAFWSWDIAVDNCAICRNHIMEPCIECQPKAMTDTDNECVAAWGVCNHAFHLHCINKWIKTRDACPLDNQPWQLARCGR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :. . . * : :* * *:*.**:.************: *****.. ..:**..*** ****** *** :*:*** .*****: * : *:", "identical_positions": 50, "similar_positions": 24, "identity": "40.0%" }, { "cls_id": "homologset.agr.SGD:S000005495", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7V2-1", "uniprot_id": "D4A7V2_RAT", "id": "D4A7V2-1", "name": "Mediator of RNA polymerase II transcription subunit 7", "aln": "MG--EPQQVSALPPPPMQYIKEYTDENIQEGLAPKP------------------------------PPP--IKDSYMMFGNQFQCDDLIIRPLESQGIERLHPMQFDHK--------KELRKLNMSILINFLDLLDILIRSPGSIKREEKLEDLKLLFVHVHHLINEYRPHQARETLRVMMEVQKRQRLETAERFQKHLERVIEMIQNCLASLPDDLPHS------EAG-----MRVKTEPMDTDDNSNCTGQNEQQRESSGHRRDQIIEKDAALCVLIDEMNERP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CZB6-1", "uniprot_id": "MED7_MOUSE", "id": "Q9CZB6-1", "name": "Mediator of RNA polymerase II transcription subunit 7", "aln": "MG--EPQQVSALPPPPMQYIKEYTDENIQEGLAPKP------------------------------PPP--IKDSYMMFGNQFQCDDLIIRPLESQGIERLHPMQFDHK--------KELRKLNMSILINFLDLLDILIRSPGSIKREEKLEDLKLLFVHVHHLINEYRPHQARETLRVMMEVQKRQRLETAERFQKHLERVIEMIQNCLASLPDDLPHS------EAG-----MRVKAEPMDTDDNSNCPGQNEQQRESSGHRRDQIIEKDAALCVLIDEMNERP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43513-1", "uniprot_id": "MED7_HUMAN", "id": "O43513-1", "name": "Mediator of RNA polymerase II transcription subunit 7", "aln": "MG--EPQQVSALPPPPMQYIKEYTDENIQEGLAPKP------------------------------PPP--IKDSYMMFGNQFQCDDLIIRPLESQGIERLHPMQFDHK--------KELRKLNMSILINFLDLLDILIRSPGSIKREEKLEDLKLLFVHVHHLINEYRPHQARETLRVMMEVQKRQRLETAERFQKHLERVIEMIQNCLASLPDDLPHS------EAG-----MRVKTEPMDADDSNNCTGQNEHQRENSGHRRDQIIEKDAALCVLIDEMNERP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZV35-1", "uniprot_id": "MED7_DANRE", "id": "Q7ZV35-1", "name": "Mediator of RNA polymerase II transcription subunit 7", "aln": "MG--EPQQVSALPPPPMQYIKEYTDENVRKGLAPKP------------------------------PPP--IRDSYMMFGNQFQCDDLIIRPLESQGIERLHPMQFDHK--------RELKKLNMSILVNFLDLLDILIKSPGSIKREEKLEDLKLLFVHMHHLINEYRPHQARETLRVMMEVQKRQRLETAERFQKHLERVVEMIQGCLSSLPDDLPLPNSSSMGEAGSAAGSSRLKTEPMDVDDVAGASCMVLQTDKNVPVKKDGVCDNDVVMCRIIDEMT---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9GYV9-1", "uniprot_id": "MED7_DROME", "id": "Q9GYV9-1", "name": "Mediator of RNA polymerase II transcription subunit 7", "aln": "MSN-QETQVSSLPMPPERYIANYTDENIRRNRAPRP------------------------------PPPPAQHEVYSMFGIQYNNDE-MIRSLESQNIKRLIPIHFDRR--------KELKKLNHSLLVNFLDLIDFLILNPDSPRRTEKIDDISLLFVNMHHLLNEFRPHQARETLRVMMEMQKRQRVETAARFQKHLERVREIVNTAFSALP-----------------------VLDDDDDSGGAKIKTEVDPLEANAAAKNDPSYQHDRMLCKLVDAIE---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08278-1", "uniprot_id": "MED7_YEAST", "id": "Q08278-1", "name": "Mediator of RNA polymerase II transcription subunit 7", "aln": "MSNDPGNEVSSLYPPPPPYVKFFTQSNLEKLPKYKEKKAASAKQTAPNNSNGGSEEEITCALDYLIPPPMPKNQQYRAFGSIWQVKD-QLPDLESMGLTQLYKKSTENESTNYQYKIQELRKLLKSLLLNYLELIGVLSINPDMYER--KVENIRTILVNIHHLLNEYRPHQSRESLIMLLEEQLEYKRGEIREIEQVCKQVHDKLTSIQDTLRTG----------------------------SQSPPSSSQ---------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :**:* ** *: :*:.*:.. : *** .: * ** :: .: : *** .: :* :.. :**:** *:*:*:*:*:..* .*. .* *:::: ::*::***:**:****:**:* :::* * . : .::: ::* : : :* . ", "identical_positions": 49, "similar_positions": 63, "identity": "17.13%" }, { "cls_id": "homologset.agr.SGD:S000005497", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VCV9-1", "uniprot_id": "MF4B1_MOUSE", "id": "Q8VCV9-1", "name": "Sodium-dependent glucose transporter 1A", "aln": "----------------------------------------MYAAFLGLGMSVAILGPTFQDLAENVNRNISSLSLIFVGRATGFLSGTMIGGVLFDHINQ-FFLLGASMVATAAGLYLIPFCKTAVLLIITMSVFGASVGVVDTGANVLILDLWGDKGAPQMQA-------LHFSFALGAFLAPLLAK--LAWG-TAPAQNHTESDLDTL--------------MLNRSSNGTSDSVFAVPDDMNLLWAYASIGTFILVVSVFLFG-------------------------LFCKKHSRQKKPRASAEGAR-------RAKYHRALLCLLF-------LFFFFYVGAEITYGSYIFSFATTH-----VGMEESEAAGLNSIFWGTFAACRGLAIFFATFLQPGTMIVLSNIGSLVSCFFLVLFDKS----PLCLWIATSVYGASMAATFP--SGISWIEQYTTLTGKSAAFFVIGSALGDMAIPAVIGILQGHY-PDLPVVLY-TCLGSAIFTAILFPVMYKLATLPLK--------REDQKALPTSSRL-----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "J3QNS5-1", "uniprot_id": "J3QNS5_MOUSE", "id": "J3QNS5-1", "name": "", "aln": "------------------------------------------MDFNAEGLSVAILGPTFPDLAKNVNRNISSLSLIFVGRASGYLCGSMIGGVLFGCINH-FLLLGVSLSATTVGLYLMPFCKTAALLIVMMSVFGVSMGILDTGGNVLILDLWGDKGAPHMQA-------LHFSFALGAFLAPLLAK--LAWGTTTSAQNYTEPQSDRL--------------ALNQSFEATSDSVFAVPDDMNLLWTYASIGTYVLVVSVFLFG-------------------------LFCKKHSRQKKPRASAEGAR-------RAKYHRALLCLLF-------LFFFFYVGAEVTYGSFVFSFAITH-----VGMEESEAAGLNSIFWGTFAACRGLAIFFATFLQPGTMIVLCNIGSLVSCFFLVLFDKS----PLCLWIATSVYGASMAATFP--SGISWIEQYTTLTGKSAAFFVIGAALGEMAIPAVIGILQGQY-PDLPVVLY-TCLGSAIFTAVLFPVMYKLATLPLECQHKGTRKREDQKALLSSSELHDCEEENEEDDAEKWNEMDFEVVEMSDPVQESARETCREEGSGQVLLDGLIAEPFSANSSNSLGNHQDKRD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PYY6-1", "uniprot_id": "E9PYY6_MOUSE", "id": "E9PYY6-1", "name": "", "aln": "MGSRGSGPTSVEQHLLQVETQGKNGLQAVGRTLRWFTTVVLNAAFLGMGVSAAVLGPTFPDLARNVNRNVSSLSEIFVGRALGYLCGSVVGGVLFDCMNH-FLLLGLSNLLTIAGLYLTPFCKTAALLTTMMSVTGVSFGVLDTGGNVLILDLWGDKGAPHMQA-------LHFSFALGAFLAPLLAK--LAWGTTTSAQNYTEPQSDRS--------------ALNQSFEATLDSVFAVPDDKNLLWTYASIGTYVLVVSVFLFA-------------------------PFFKKNSKQKKSEASAQGAR-------RAKYHRALLCLLF-------LFFFFYVGAEVTYGSFVFSFAITH-----VGMEESEAAGLNSIFWGTFAACRGLAIFFATFLQPGTMIVLCNIGSLVSCFFLVLFDKS----PLCLWIATSVYGASMAATFP--SSISWIEQYTSINGKSAAFILIGAALGLMATPALSGILQGHY-PDLPVVLY-TCLGSAVLTTVLFPVMYKVATLPLDQKQEKSINSEGQKTLLSSFRLIKEAK------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PDC8-1", "uniprot_id": "S60A1_MOUSE", "id": "Q6PDC8-1", "name": "Solute carrier family 60 member 1", "aln": "--------------------MGCDGRVSELLRRNLQPTLTYWSVFFSFGLCIAFLGPTLLDLRCQTHSSLPQISWVFFSQQLCLLLGSALGGVFKRTLAQSLWALFTSTLVISLVFAVIPFCHDVKVLASVIALAGLAMGCIDTVANMQLVRIYQKDSAFFLQV-------LHFFVGLGALLSPLIADPFLSEANCFPANNTANATSRSHGSRVLSQHHAAAQPWINQTIPRLPPKEVTENHVSYAFWIMALINLPVPLAVLFLLSKERLLTCAQRKPLLLSADELALETRPAEKEDTSSLAPKFQPHSGQEDLFSCCQRKNFRGAPCSFFAIHITAALVLFMTDGMMGAYSAFVYSYAVEKP----LSIGHKSAGYLPSLFWGFITLGRFISIPVSSRMRPATMVFINVVGVVVTFLMLLIFSYN----VIFLFVGTASLGLFLSSTFP--SMLAYTEDILQYKGCATTVLVTGAGIGEMVLQMLVGLIFQAQ-GSYSFLVCGVIFGCLAFIFYILLLFFHRIHPELS-----SVLTQDKALGVENPECYQR--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08280-1", "uniprot_id": "BSC6_YEAST", "id": "Q08280-1", "name": "Bypass of stop codon protein 6", "aln": "-------------MDASSVPPKVDDYGMYTTEISHHNPIELKNLLSSSDSRRNSQDEDSLPNNTNLIKEIDWQGEKVKTYPLNYQTVPLVKLQVIACLIMFVVFGMNDQTVGALLPTLIEYYHISRVDVSNVFIVQLCGYVMASLSKERLNKHFGMRGGMLLAAGLCIVFLIILATAPSSFYVCMFCGLPLGLGIGILDSTGNVLMGSLLVHKN---------ELMGIMHGLYGAAAMVTPPLVSYFVEWGHWSLFFLIPLFFSIIGMIVIFPAFKFETASKYDYLCSVENKESNNDVEEAGDNSLMESTKASPG---FFELLRNPAIFLYS------LYLFLYLGAEITTGSWFFSYLLETKSSNKVAMSYIAASFWTGLTVGRLCLGFVTERFFENEYKASKAYAFLTLSSYTLFVLVGLINSSSVFYFVVLFFVVFCCGTFIGPLFPNASIVALQVLPKRLHVSGVGVAVAVGGCGGAAIPYLAGVIAHTVGIQYIPLLCWIMVALFTLEWTLYPKFIKGHEEYF---------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . : .: . . . : . : . . : : : : : : . : : .: : : .. : . : : . .:: ::. *. . .. :. .. : . . . : .* : ::. . . .. : : * :: * :*: * : .::.:*: :.: *. .: * : . . :... : :. . .:: ::. . : *:. . * :.. ** * :: .. . : .. * . : *:: . :: .. : : : : : ", "identical_positions": 16, "similar_positions": 129, "identity": "2.58%" }, { "cls_id": "homologset.agr.SGD:S000005498", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V8L0-1", "uniprot_id": "G3V8L0_RAT", "id": "G3V8L0-1", "name": "GATOR2 complex protein WDR24", "aln": "----------------------------------------------------------------------------------------------------------------MEKMSRVTTALSGSALTGRTMHCHLDAPANAISVCRDAAQ--VVVAGRSIFKIYAIE-----------------------EEQFVEKLNLRVGRKPSLNLSCADVVWHQMDENLLATAATNGVVVTWNLGRPS--RNKQDQLFTEHKRTVNKVCFHPTEAHVLLSGSQDGFMKCFDLRRKDSVS------TFSGQSESVRDVQFS------------------IRDYFTFASTFENGNVQLWDIRRPDRCERMFTAHNGPVFCCDWHPEDRGWLATGGRDKMVKVWDMTTHRAKEIHCVQTIAS-----------------------------VARVKWRPECRHHLATCSMMVDHN-----IYVWDVRRPFVPAAMFEEHR--------------DVTTG---IAWRHPHDPSFLLSGSKDSTLCQHLFRDASQPVERAN------------------------------PEGLCYGLFG-------------------------------DLAFAVKESLVAAES-----GRKPYAG-DRRHPIF--FKRKLDPAEPFSGLASSALS-------VFETESGGGS-MSWFVDTAERYALAGRPLAELCDHNAKVAR----------------------------------ELGRNQVAQTWTMLRIIYCSPGLVSSANLNHSVGKGSSCSLPLMNSFNLKDMGPGLGSETRLDRSKGDT----------------------------------------------------------RSDTVLLDSSATLITNEDNEETEGS------------------------DVPADYLLGDVEGEEDELYPLDTEHVHPEEPEYVLPQEAFPLRHEIVDTPSGP------------------------EHLQDKADSPHVSGNEADTASLAPVDSSSSLLS----------------------------------------------------------------------------------------------------VSHALYDSRLPPDFFSVLVRDMLHFYAEQGDVQMAVSVLIVLGER-VRKDIDEQTQEHWYTSYIDLLQRFCLWNVSNEVVKLSTSRAVSCLNQASTTLHVNCSHCKRPMS-----------------------SRGWVCDRCRRCAS-MCAVCHHVVKGLFVWCQGCSHGGHLQHIMKWLEGSS--HCPAGCGHLCEYS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CFJ9-1", "uniprot_id": "WDR24_MOUSE", "id": "Q8CFJ9-1", "name": "GATOR2 complex protein WDR24", "aln": "----------------------------------------------------------------------------------------------------------------MEKMSRVSTALSGSALTGRTMHCHLDAPANAISVCRDAAQ--VVVAGRSIFKIYAIE-----------------------EEQFVEKLNLRVGRKPSLNLSCADVVWHQMDENLLATAATNGVVVTWNLGRPS--RNKQDQLFTEHKRTVNKVCFHPTEAHVLLSGSQDGFMKCFDLRRKDSVS------TFSGQSESVRDVQFS------------------IRDYFTFASTFENGNVQLWDIRRPDRCERMFTAHNGPVFCCDWHPEDRGWLATGGRDKMVKVWDMTTHRAKEIHCVQTIAS-----------------------------VARVKWRPECRHHLATCSMMVDHN-----IYVWDVRRPFVPAAMFEEHR--------------DVTTG---IAWRHPHDPSFLLSGSKDSTLCQHLFRDASQPVERAN------------------------------PEGLCYGLFG-------------------------------DLAFAVKESLVAAES-----GRKPYAG-DRRHPIF--FKRKLDPAEPFSGLASSALS-------VFETESSGGS-MSWFVDTAERYVLAGRPLAELCDHNAKVAR----------------------------------ELGRNQVAQTWTMLRIIYCSPGLVSSANLNHSVGKGSSCGLPLMNSFNLKDMGPGLGSETRLDRSKGDT----------------------------------------------------------RSDAALLDSSATLVTNEDNEETEGS------------------------DVPADYLLGDVEGEDDELYPLDTEHVHSEEPEYVLPQEAFPLRHEIVDTPSGP------------------------EHLQDKADSPHVSGNEADTASLAPVDSSSSLLS----------------------------------------------------------------------------------------------------VSHALYDSRLPPDFFSVLVRDMLRFYAEQGDVQMAVSVLIVLGER-VRKDIDEQTQEHWYTSYIDLLQRFCLWNVSNEVVKLSTSRAVSCLNQASTTLHVNCSHCKRPMS-----------------------SRGWVCDRCHRCAS-MCAVCHHVVKGLFVWCQGCSHGGHLQHIMKWLEGSS--HCPAGCGHLCEYS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96S15-1", "uniprot_id": "WDR24_HUMAN", "id": "Q96S15-1", "name": "GATOR2 complex protein WDR24", "aln": "----------------------------------------------------------------------------------------------------------------MEKMSRVTTALGGSVLTGRTMHCHLDAPANAISVCRDAAQ--VVVAGRSIFKIYAIE-----------------------EEQFVEKLNLRVGRKPSLNLSCADVVWHQMDENLLATAATNGVVVTWNLGRPS--RNKQDQLFTEHKRTVNKVCFHPTEAHVLLSGSQDGFMKCFDLRRKDSVS------TFSGQSESVRDVQFS------------------IRDYFTFASTFENGNVQLWDIRRPDRCERMFTAHNGPVFCCDWHPEDRGWLATGGRDKMVKVWDMTTHRAKEMHCVQTIAS-----------------------------VARVKWRPECRHHLATCSMMVDHN-----IYVWDVRRPFVPAAMFEEHR--------------DVTTG---IAWRHPHDPSFLLSGSKDSSLCQHLFRDASQPVERAN------------------------------PEGLCYGLFG-------------------------------DLAFAAKESLVAAES-----GRKPYTG-DRRHPIF--FKRKLDPAEPFAGLASSALS-------VFETEPGGGG-MRWFVDTAERYALAGRPLAELCDHNAKVAR----------------------------------ELGRNQVAQTWTMLRIIYCSPGLVPTANLNHSVGKGGSCGLPLMNSFNLKDMAPGLGSETRLDRSKGDA----------------------------------------------------------RSDTVLLDSSATLITNEDNEETEGS------------------------DVPADYLLGDVEGEEDELYLLDPEHAHPEDPECVLPQEAFPLRHEIVDTPPGP------------------------EHLQDKADSPHVSGSEADVASLAPVDSSFSLLS----------------------------------------------------------------------------------------------------VSHALYDSRLPPDFFGVLVRDMLHFYAEQGDVQMAVSVLIVLGER-VRKDIDEQTQEHWYTSYIDLLQRFRLWNVSNEVVKLSTSRAVSCLNQASTTLHVNCSHCKRPMS-----------------------SRGWVCDRCHRCAS-MCAVCHHVVKGLFVWCQGCSHGGHLQHIMKWLEGSS--HCPAGCGHLCEYS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVL2-1", "uniprot_id": "WDR24_DANRE", "id": "Q7ZVL2-1", "name": "GATOR2 complex protein WDR24", "aln": "----------------------------------------------------------------------------------------------------------------MEKMTRVST------INGRTMFCHLDAPANAISVCRDATQ--VVVAGRNIFKIYGLE-----------------------EDGFVERLNLRVGRKPSLNFSCADVMWHQMEENLLATAATNGAVVTWNLSRPC--RNKQEQLFTEHKRTVNKVCFHPTEVNMLLSGSQDGFMKCFDLRKKESVS------TFSGQSESVRDVQFS------------------MKDYFTFAASFENGNVQLWDIRRPDRYERMFTAHTGPVFCCDWHPEDRGWLATGGRDKMVKVWDMSTNRVKEIYCVQTFAS-----------------------------VARVKWRPERRYHLATCSMMVDHN-----IYVWDVRRPFIPFATFEEHK--------------DVTTG---IVWRHQHDPYFLLSGSKDSTLYQHMFKDASRPVDRAN------------------------------PEGLCFGLFG-------------------------------DLAFAAKESLMSAPASAGDVGRKTYPGGDRRYPIF--FFKKPDVTEQFA-QVSSALS-------VFESEADSSAGMDWFINTAQSYLLSGKPFAELCEHNAHVAK----------------------------------SLNRPQESTTWTMLRIMFSEP-ANPSLSTNHNLNK--SGNLPLVNSFSMKEMSGALN-----ERNKENR----------------------------------------------------------QDNIHSLET--NLNNNDENEETEGS------------------------EGQAEYLFVDDELDDDELYSMEHDNQPAEESEYLLPQEAFPLRHEIMDHPSAP------------------------EPLQEKQESPHVSGSEAESMCLTPMES-FSLIS----------------------------------------------------------------------------------------------------VSQQLFSPHLPPKFFCPIVKEMLCYYAEQGDVQMAVSVLIVLGDR-IRKEIDELMQEHWYMSYIDLLQRFELWNVSNEVIKLSTCGAIMCLNQASTTLHINCSNCKRPMS-----------------------NKGWICDRCHQCAS-VCAVCHHVVKGLFVWCQGCSHGGHLEHVMEWLKQSK--HCPAGCGHLCEYT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XZ25-1", "uniprot_id": "WDR24_DROME", "id": "Q9XZ25-1", "name": "GATOR2 complex protein Wdr24", "aln": "----------------------------------------------------------------------------------------------------------------MPDSVEDTS--------TISLRICLEGHANALALNKDNNQ--IALAGRSLLKVYSIN-----------------------SNGFTESCNMR-GKNQNLSYSANDVAWSTLDSNLLATAATNGVVSVWDLSKFG--RQKQLLVYNEHERTAHTVTFHSSEPNILISGSQDGTIKCFDIRSDKSIN------TYFCNSESVRDVKFS------------------PHTQNIFSAVSENGTVQLWDMRKWDKCMVQFTAHYGPVYTCDWHP-TRNWLATGSRDKQIKVWNMD-GRPGLEHTIHTIAV-----------------------------VGRVKWRPERTYHIASCALVVDYS-----VHVWDIRRPYIPFASFNEHT--------------NVTTG---IAWQG-SDSHCLLSISKDSTIYKHAFKDATRPALKAN------------------------------AQGASLGRFG-------------------------------DISFANKIKEYEPKTSG-ASNTKSSSFIRRKTNVAGSIQFHLDHSKMYKFMVNDTFSGYP----LSESVSRPTQEHESFIGCARELVISGKKLSELCEHNAEVSK----------------------------------KYGKHNATTLWNFIKLFYGSNHFEPPFEHRSSFSN----QKNPMNSRRATQVASDWPQ----QRTELGQ----------------------------------------------------------DLNGNTPETAHEIDVANVDDDTLGS------------------------SGVEHPPTSSVILSETQIIS----EITFDNFELLRNGFIYVGPTECPKALAFP------------------------ALHHDVQAARPQLDLKASDHEKSPPPHVPTVLK----------------------------------------------------------------------------------------------------VSHVPPIPMWEPHKF---VSDALMLMNDVGDVQTALTVLIALGEARKLLPIDDALVEHWFYTYVDQLHRYELWNEACEVINRSWLRSVQQLNQHSTAMHTNCGECGRPMGG----------------------KVGWYCDKCKSMQSAKCCVCGLIVRGVYAWCQGCSHGGHIEHLQKYFAKHS--KCPK-CGHLCAYS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08281-1", "uniprot_id": "RTC1_YEAST", "id": "Q08281-1", "name": "Restriction of telomere capping protein 1", "aln": "MSLSPHVENASIPKGSTPIPKNRNVSSIGKGEFLGSSSSNNSSFRMNHYSNSGQPSVLDSIRRPNLTPTFSYSNGVYMPESHRTSSFNDSYLPYDKNPYAKTTGSMSNKSNMKIKTKKNAINTNTRKSSGLIYTTKVDKELSSIDKVNDPNINGLVCAGKTHLGLYKFSPSDRSIKCVHDFITPNSNTSTRGTTSLLPKLSKRTRQNKFSTIADVKTGFNNYKN-CIAVCNNSTAISIYDLNKSSSIDNPLITSLCEHTRSINSFDFNMVESNLIISGGQDSCVKIWDLRSNKSKSSNRSDISINTASDSIRDVKWMPGYNFASKNDQGSSTYGNLKSGYKFASIHDSGYLLKFDLRQPAQYEKKLNAHTGPGLCLNWHP-NQEYIATGGRDGKCCLWFVGDNANAAENTVLNYGNSPSLHAPNTSLNNSGSLAFPKLTINTGYPVTKLKFKPAYSSNIYNSLLGISSMGDEAEVRIYSLARKYIPKHVLLSETPSLGLVWWDENLIFNIDKGTRINGWDINKEPTVLENLSKNTTTWRDLDGNGLLSVDQEIGSYEVVEPELQPTSSTTCKKHPGTIKNPKNGNPENQGIIGGIKKGFSHTGLTSFTPERPPTLKAGPTFSTKSLTLASGASSFNSSSAS-LTSLTPQTENREEIAIEPPCIITLDIPQIFNNIRLTKIAHSRKKNVISESSSMKNSPVEKFKYLARQLKFSYIREHNVSDSADTAYKNDIENIDVVKNATETHGDNTTTTNNNDDGDDDDDDDDDDKIIESHLLKKYNFPENNTWATLMNEKVNNKKSKRNSSSSREFDEKDVRSSISSISASRQSHDRARKIDKNVEAELQEKIQTLVDLISIATHNASVYLSIDDLTNFKIWILIRDSLLWDLKWMTSSQISSDNASNMDANESSDFEAGENLKTGKEFPEEDGAGTSGAESLVEERPQAFRANSDEPSDAEKKPVSKLKEQLKNTEIIPYAQPNEDSDEVLTKLKELQNQRLESRTKMGETVSDDVIIEEDEHEHQEEEQPHDSPTKSAQFHASPIAKSIPILQKREHRKSFIDTFMLHSPNGYNGDTDIGNEDDNISPRFTYNSVSPRSKVSSLQSYATTTSQLETFKKLSSHTAPIIGSPRHAPSRPDSIGREQLSSSLTKKLAKCKKIIADPPWDTKKLIKQLYNQATETGNVVLTVNILFLFQTIYQITEID--IAKDAIAHFLLLLHRYELFGIAADVLKYCPFEDIMGSEGDQSSIRLFCERCGELITNESSKEKLRAEAQQTGNKKIMDKFGYWYCDSCKKKNT-SCVLCERPLKKLTMVILPCGHEGHFQCIQEWFLDENEQECPGGCPGVAFI-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : :: .:: .* :. **:. : :* :. : . * :: . : .. : .. :*.. .. .: ::*.: : ** *: :.. *: * ::::**.**. :* :*:* ..* . : *:*:***:: : *:: :.* : :*:*: : :.** ** :*** : ::***.** :* : : . . * ::*::* :: .. : :. : ::.: * ::* : .. :: .* * :. * . **::: :. :. .. : : * :* .:::* . . : . .. . .. : * .: : :: : *: . * *. :: ::.: . : . . : : : : . .. . .: .. .:: :.. . :. : : .: *. . . .: : . .: * : * :: :: :* .::. ::: * : : : *:* ::.:*: : ** :. :: *:*: *:. : :*:: . : : .:::: * .* . : * ** *: : * :* :: : *.* **:: : ::: . .** * :. ", "identical_positions": 88, "similar_positions": 253, "identity": "6.53%" }, { "cls_id": "homologset.agr.SGD:S000005499", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63073-1", "uniprot_id": "IF4E_MOUSE", "id": "P63073-1", "name": "Eukaryotic translation initiation factor 4E", "aln": "------------------------------------------------------------------------------------------------------------MATVEP-----------ETTPTTNPPPAEEEKTESNQEVAN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PEHYIKHPLQNRWALWFFK-----NDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLET----------------------------------LLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63074-1", "uniprot_id": "IF4E_RAT", "id": "P63074-1", "name": "Eukaryotic translation initiation factor 4E", "aln": "------------------------------------------------------------------------------------------------------------MATVEP-----------ETTPTTNPPPAEEEKTESNQEVAN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PEHYIKHPLQNRWALWFFK-----NDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLET----------------------------------LLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06730-1", "uniprot_id": "IF4E_HUMAN", "id": "P06730-1", "name": "Eukaryotic translation initiation factor 4E", "aln": "------------------------------------------------------------------------------------------------------------MATVEP-----------ETTPTPNPPTTEEEKTESNQEVAN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PEHYIKHPLQNRWALWFFK-----NDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLET----------------------------------LLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DFS6-1", "uniprot_id": "IF4EA_DANRE", "id": "Q9DFS6-1", "name": "Eukaryotic translation initiation factor 4E-1A", "aln": "------------------------------------------------------------------------------------------------------------MATAEP-----------ETS--TNPSNSEEKNEENEQQIVS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LEDYIKHPLQNRWALWFFK-----NDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMSGCDYSLFKDGIEPMWEDERNKRGGRWLITLSKQQRRADLDRFWLET----------------------------------LLCLVGEAFDDHSDDVCGAVVNIRTKGDKIAIWTTDYENKDAIVHIGRVYKERLGVPPKVIIGYQSHADTATKSGSTTKNKFVV-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58H109-1", "uniprot_id": "A0AC58H109_DANRE", "id": "A0AC58H109-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------MATSEPVRGIGLGSFRASQLPEMRGTETEEVRADSPTAVVTTS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PEQYIKHPLQNRWALWYFK-----NDKSKSWTENLRLISKFDTVEDFWALYNHIQQPSKLGFGCDYCLFKDGIKPMWEDDRNKLGGRWLMTLSKQQRHNDLDRYWMETVIVFFFFFLLGSYILIDSWMCISDCPCVCHLLLQLLCLIGESFDEASEDVCGAVVNVRPKGDKIAIWTGNCQNRDAIMTIGQQYKERLSLPSKTLIGYQSHDDTSSKSGSTTKNMYSV-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3UTA9-1", "uniprot_id": "I4E1B_MOUSE", "id": "Q3UTA9-1", "name": "Eukaryotic translation initiation factor 4E type 1B", "aln": "---------------------------------------------------------------MNKVEGGGHKEEVVVKEKE-------------------VVKEKPSEATAEG-----------VQAGEAKDLPGSLKTQRRKAHREHPP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EVLSKLHPLQYRWVLWFFK-----NDRSRAWQDNLQLVTKFNTVEDFWAVYSHIKLASKLSSGCDYALFKEGILPMWEDNRNKQGGRWLLSIDKQLRHFELDRLWLET----------------------------------LLCLVGNCFEEYSREVCGAVVNIRTKRDKIALWTSEAEDKAGVMQIGQIYKERLGISTKTIIGYQAHADTAAKSNNLAN-KFVV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A3E5-1", "uniprot_id": "A0A8I6A3E5_RAT", "id": "A0A8I6A3E5-1", "name": "Eukaryotic translation initiation factor 4E", "aln": "MLVRPLLLLVLYSSLSCQEVAPDANFPPPSQLQSQCANCQTDYRTQERTLEASLQGRRELEAQMSKAEGEGQEEEEEEEEEEEKEEEEEEEEEEKEEEEEEEVKEKPSEATAEG-----------LQG-EARDLPGSLKTVKQKAQREHPT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLPRELHPLQFRWVLWFFK-----NDRSRAWQDNLQLVTKFDTVEDFWATYRHVKLASKLSCGCDYALFKEGIQPMWEDSRNKRGGRWLLSLAKQQRHMELDRLWLET----------------------------------LLCLLGESFEEYSGEVCGAVVNIRTKGDKIALWTSEAENKAGVMHIGHIYKERLGLSTKTIIGYQAHADTAAKSNSLAKNKFVV-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NMX2-1", "uniprot_id": "I4E1B_HUMAN", "id": "A6NMX2-1", "name": "Eukaryotic translation initiation factor 4E type 1B", "aln": "----------------------------------------------------------MLAVEVSEAEGGIREWEEEEKEEE------------------------AAERTPTG-----------EKS---PNSPRTLLSLRGKARTGGPM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EVKLELHPLQNRWALWFFK-----NDRSRAWQDNLHLVTKVDTVEDFWALYSHIQLASKLSSGCDYALFKDGIQPMWEDSRNKRGGRWLVSLAKQQRHIELDRLWLET----------------------------------LLCLIGESFEEHSREVCGAVVNIRTKGDKIAVWTREAENQAGVLHVGRVYKERLGLSPKTIIGYQAHADTATKSNSLAKNKFVV-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PW28-1", "uniprot_id": "IF4EB_DANRE", "id": "Q9PW28-1", "name": "Eukaryotic translation initiation factor 4E-1B", "aln": "-----------------------------------------------------------------------------------------------------------MASCAVQ-----------LID----KVPK--KKVEKKKFEPNIL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KEPCMKHPLQNRWGLWFYK-----NDKSKMWQDNLRLITKFDTVEDFWGLYNNIQLPSKLSSGCDYSMFKDGIEPMWEDRSNKCGGRWLITLAKQHRHTELDHFWLET----------------------------------LLCLIGEGFSSFSRDICGSVINIRAKGDKIALWTSNAENCETVTYIGRKYKESLGLPQKLVIGYQAHADTATKSNSITKNKFVV-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48598-1", "uniprot_id": "IF4E_DROME", "id": "P48598-1", "name": "Eukaryotic translation initiation factor 4E1", "aln": "-----------------------------------------------------------MQSDFHRMKNFANPKSMFKTSAP-----------------------STEQGRPEP---------PTSAAAPAEAKDVKPKEDPQETGEPAGNTATT----------------------------------------------------------------------------------------------------------------------------------------------------------------TAPAGDDAVRTEHLYKHPLMNVWTLWYLE-----NDRSKSWEDMQNEITSFDTVEDFWSLYNHIKPPSEIKLGSDYSLFKKNIRPMWEDAANKQGGRWVITLNKSSK-TDLDNLWLDV----------------------------------LLCLIGEAFD-HSDQICGAVINIRGKSNKISIWTADGNNEEAALEIGHKLRDALRLGRNNSLQYQLHKDTMVKQGSNVKSIYTL-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VRY0-1", "uniprot_id": "Q9VRY0_DROME", "id": "Q9VRY0-1", "name": "eIF-4F 25 kDa subunit", "aln": "--------------------------------------------------------------------MLTTQQTEFKMMDN-----------------------GTETLADSP---------SSSSEDLKTLSDMDIRKPVTEIVDLR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKHPLENTWTLWYLE-----NDRSKNWEDMQNEITSFDMVEDFWSLYNHIKQPSEIRVGSDYSLFKKGIQPMWEDDANKFGGRWVINMGRGSK-AELDKLWLDV----------------------------------LLILIGEAFE-NTEEVCGAVINLRGKSNKISIWTANGHNELAVMEIGLKLRDLLVLPP-HQLQYQLHKDTMCKQGSVIKAVYCV-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W5B3-1", "uniprot_id": "Q9W5B3_DROME", "id": "Q9W5B3-1", "name": "eIF-4F 25 kDa subunit", "aln": "----------------------------------------------------------MLPNSFYRMRDFANPRTMFKSCAN-----------------------NNEYPTQGPQKVESPTDVTQPAAAPQSTEDTQPEKTQEPMNDPNKTSPSEPQKRGKGNRKGKKNQKNAPRTPSQTSKSSRSNNPGKDGKSTGNDDNEKGKGQGKQMVQQKENSPEQEQSTSAQYRKNVLDKDLQDKKLIEKNMQGKIITQENLLGQKVLMRLSEQKLLSLRLEPRIKQNTCPPAKKEDAVVAFDNSLEFLSLNNKCDDDLTIAAENAELLEVEDPQHPLNNCWTLWYLE-----NDRNKSWEEMLHKVTSFDTVEKFWSLITHIKPPSELMLGSDYSLFKKGIRPMWEDEANVNGGRWVINLTKSAK-MALDSFWMDA----------------------------------MLCLIGEACK-HSDDLCGVVVNIRGKSNKISIWNADGGNQTTVLEIGRILRKVLRMDNIYVLEYQLHKDSKDKLGSTVKRIYTV-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VSB6-1", "uniprot_id": "Q9VSB6_DROME", "id": "Q9VSB6-1", "name": "eIF-4F 25 kDa subunit", "aln": "------------------------------------------------------------------MASAQVQSFDIMKQQD-----------------------QQHQLNSIH---------KHHHH----HEGVPLESNSPEPIDEEI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YQVEYKHPLEHVWTLWYLE-----NDRTKHWKDMLNEITEIDSVETFWSLYHTIKTPAELKIGCDYSVFKKGIKPMWEDEANIKGGRWLVTVSKSAK-AELDQIWLDI----------------------------------LLLMVGQNFE-YSDEICGAVINIRNKSNKISVWTANGSNEMAILEIGQKLKILLHLQS-HSLQYQLHSDAMSKFNSGVKSVYTL-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VSG1-1", "uniprot_id": "Q9VSG1_DROME", "id": "Q9VSG1-1", "name": "eIF-4F 25 kDa subunit", "aln": "------------------------------------------------------------------MVYTGYVSNGLQNAEE-----------------------TAWVPYGDP---------NDWSHGLAVYDGLELMSGNEEELQPSLNRVMK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------NIDYDLAMKHPLEHTWTLWHLE-----NDRTKRWAEMLVDVTSFNTVEDFFSVYYFVKPPSDLKIFNDYMVFKKNIRPMWEDDTNKNGGRWILLLDKASR-TYIDKMWHDL----------------------------------LLCMIGECFQ-HSDEICGVVINVRNKANKLSLWTKDSRNVEAILSIGRQIKELLHLGI-MEIQYQVHKDAMVNHGPNVNAIYTL-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAR1-1", "uniprot_id": "Q9VAR1_DROME", "id": "Q9VAR1-1", "name": "eIF-4F 25 kDa subunit", "aln": "-------------------------------------------------------------------------MENLRQTKE-----------------------SSEFKMGTS------------------LDNNKLASLGATN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHRLQNTWTLWGVK-----YDPEISWEDMLKEIDSFNTVEDFWNLYFRIDTPSKLNRGCDYMLFKKGIRPMWEDPPNKGGGRWTYKVDKRST-AELDKTWLDV----------------------------------LLCMIGEACD-HCDQICGAFVRIRKNINKISVWTKADAGDECNEQC-------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07260-1", "uniprot_id": "IF4E_YEAST", "id": "P07260-1", "name": "Eukaryotic translation initiation factor 4E", "aln": "---------------------------------------------------------------------------------------------------------MSVEEVSKK---------------FEENVSVDDTTATPKTVLSDS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AHFDVKHPLNTKWTLWYTKPA---VDKSESWSDLLRPVTSFQTVEEFWAIIQNIPEPHELPLKSDYHVFRNDVRPEWEDEANAKGGKWSFQLR--GKGADIDELWLRT----------------------------------LLAVIGETIDEDDSQINGVVLSIRKGGNKFALWTK-SEDKEPLLRIGGKFKQVLKLTDDGHLEFFPHSSANGRHPQPSITL--------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "O60573-1", "uniprot_id": "IF4E2_HUMAN", "id": "O60573-1", "name": "Eukaryotic translation initiation factor 4E type 2", "aln": "-----------------------------------------------------------------MNNKFDALKDDDSGDHD-----------------------QNEENSTQK-----------DGEKEKTERDKNQSSSKRKAVVPG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PAEHPLQYNYTFWYSRRTPGRPTSSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRLRKGLASRCWENL--------------------------------------ILAMLGEQFM-VGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSIKMPGRLGPQRLLFQNLWKPRLNVP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : :* . : : . ** *: : . .: *: :*:..: * *** * **:* : : :* ::*: :: * .: :* : :::*. . ", "identical_positions": 21, "similar_positions": 35, "identity": "3.74%" }, { "cls_id": "homologset.agr.SGD:S000005501", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIA3-1", "uniprot_id": "TYW4_RAT", "id": "Q5XIA3-1", "name": "tRNA wybutosine-synthesizing protein 4", "aln": "--------------MGPRSRQRRTGTVQSTNDSSSLSKR---------SLAAQGYVSDA------FAPLLVPGIVRRTPLIHRGYYVRARAVRHCVRAFLDLTGAIRSPTRAQILSLGSGSDSLYFRLKAAG------LLTRTAVWEVDFPDVSRLKAKRIEETPELCAQTGPFKIG---DSASTLCFESSDYRILGADLRELQRLGEALDSAGL-DATSPTLILAEAVLTYLEPSRAAALIAWVAQRFPNALFVIYEQMKPG---DAFGQIMLQHFRRLNSPLHGLELFPDVEAQRQRFLQAGWTTCSALDLNEFYRRLIPADERRRVETLEPFDEFEEWHLKCSHYFILAASRGDILSETPVFLPSEASFQIDPALPSGFLSASVVTSDHQHSSLQRYGHTSVLLSPGIIFSAGGFGEQEGRHCRVSRFHLLSRSCDSEWKGCQISTLGTEGQWDGRLYHTMTRLS-DTRVLVLGGRLSPVNPASGALQLDIYKSEDNCPEGQNVVVTKAALEEGSMLSCWRHSTTEVYYQNQRYLFVYGGRSVTDPVLSDCRFLHVETMAWVRIPVQGSSPEGRHSHSACSWQGGALIAGGLGASEEPLSSVFFLRPVS--SGFLWESIHIQPSITPRY-SHTAHVFNGKLLLVGGVWIHSSSVPGVTVISLTTGLSSEYQIDTASVPWP--LMLHNHSSALLPEEQQLLLIGGGGNCFSFGTYFNPHTVGLDLSSLGLGQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BYR1-1", "uniprot_id": "TYW4_MOUSE", "id": "Q8BYR1-1", "name": "tRNA wybutosine-synthesizing protein 4", "aln": "--------------MGPRGRQRRAGTVQSTNDSSSLSKR---------SLAAHGYVRDP------FAALLVPGPVRRTPLIHRGYYVRARAVRHCVRAFLELTSALPSRTRAQILSLGSGSDSLYFRLKAAG------LLARAAVWEVDFPDVSRLKAERIEETPELRAQTGPFKIG---DSASSLCFESADYRILGADLRELQRLGEALDGAGL-DATSPTLLLAEAVLTYLEPSSATALIAWAAQRFPDALFVIYEQMQPG---DAFGQIMLQHFQRLHSPLHGLELFPVVKAQRQRFLQAGWTACSALDLNEFYRRLLSAEERQRVETLEPFDEYEEWHLKCSHYFILAASRGDILSETPVFEPSEASFQIDPASPSGFLSARVVTSDHQHSSLKRYGHASALLSPGVIFSAGGFGEQEGRHCRVSRFHVLSRSCDSEWEGCQISTLGTEGQWDGRLYHTMTRLS-DTRVLVLGGRLSPVSPASGALQLDLYKSKDNCSEGQNVTVTKAALEEGSVLSCWRHSTTEVYYQNQRYLFVYGGRSVAEPVLSDCRFLHVETMAWVRIPVQGASPEGRHSHSACSWQGGALIAGGLGASEELLSSVLFLKPVS--SGFLWESIDIQPSITPRY-SHTAHVFNGKLLLVGGVWIHSSSVPGVTVICLTTGLSSEYQIDTASVPWP--LMLHNHSSALLPEEQQLLLIGGGGNCFSFGTYFNPHTVALDLSSLRSGQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60294-1", "uniprot_id": "TYW4_HUMAN", "id": "O60294-1", "name": "tRNA wybutosine-synthesizing protein 4", "aln": "--------------MGPRSRERRAGAVQNTNDSSALSKR---------SLAARGYVQDP------FAALLVPGAARRAPLIHRGYYVRARAVRHCVRAFLEQIGAPQAALRAQILSLGAGFDSLYFRLKTAG------RLARAAVWEVDFPDVARRKAERIGETPELCALTGPFERG---EPASALCFESADYCILGLDLRQLQRVEEALGAAGL-DAASPTLLLAEAVLTYLEPESAAALIAWAAQRFPNALFVVYEQMRPQ---DAFGQFMLQHFRQLNSPLHGLERFPDVEAQRRRFLQAGWTACGAVDMNEFYHCFLPAEERRRVENIEPFDEFEEWHLKCAHYFILAASRGDTLSHTLVFPSSEAFPRVNPASPSGVFPASVVSSEGQVPNLKRYGHASVFLSPDVILSAGGFGEQEGRHCRVSQFHLLSRDCDSEWKGSQIGSCGTGVQWDGRLYHTMTRLS-ESRVLVLGGRLSPVSPALGVLQLHFFKSEDNNTEDLKVTITKAGRKDDSTLCCWRHSTTEVSCQNQEYLFVYGGRSVVEPVLSDWHFLHVGTMAWVRIPVEGEVPEARHSHSACTWQGGALIAGGLGASEEPLNSVLFLRPIS--CGFLWESVDIQPPITPRY-SHTAHVLNGKLLLVGGIWIHSSSFPGVTVINLTTGLSSEYQIDTTYVPWP--LMLHNHTSILLPEEQQLLLLGGGGNCFSFGTYFNPHTVTLDLSSLSAGQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08282-1", "uniprot_id": "TYW4_YEAST", "id": "Q08282-1", "name": "tRNA wybutosine-synthesizing protein 4", "aln": "MKNLTTIKQTNKNVKQERRKKYADLAIQGTNNSSIASKRSVELLYLPKLSSANNFQMDKNNKLLEYFKFFVPKKIKRSPCINRGYWLRLFAIRSRLNSIIEQT---PQDKKIVVVNLGCGYDPLPFQLLDTNNIQSQQYHDRVSFIDIDYSDLLKIKIELIKTIPELSKIIGLSEDKDYVDDSNVDFLTTPKYLARPCDLNDSKMFSTLLNECQLYDPNVVKVFVAEVSLAYMKPERSDSIIEATSK-MENSHFIILEQLIPKGPFEPFSKQMLAHFKRNDSPLQSVLKYNTIESQVQRFNKLGFAYVNVGDMFQLWESADEAT-KKELLKVEPFDELEEFHLFCHHYVLCHATNYKEFAFTQGFLFDRSISEINLT-----VDEDYQLLECECPINRKFGDVDVAGN-DVFYMGG------SNPYRVN--EILQLSIHYDKIDMKNIEVSSSEVPVARMCHTFTTISRNNQLLLIGGRKAPHQGLSDNWIFDMKTREWSMIKS---------------LSHTRFRHSACSLPDGNVLILGGVTEGPAMLLYNVTEEIFKDVTPKDEFFQNSLVSAGLEFDPVSKQGIILGGGFMDQTTVSDKAIIFKYDAENATEPITVIKKLQHPLFQRYGSQIKYITPRKLLIVGGTSPSGLFDRTNSIISLDPLSETLTSIPISRRIWEDHSLMLAGFSLVSTSMGTIHIIGGGATCYGFGSVTN---VGLKLIAIAK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: ::*.**:** *** :*..: * : ::** :*:* *:***::* *:* :.:::: : ::.**.* *.* *:* :. *.:. ::*:.*: : * : * *** * : : :. : :..* **.: : . *. . * *. .:::**. *:*::*. : ::* .:: : :: *:: **: * :.*.: ** **:: .***:.: : :::* :** : *:: .. *: :::. * ::.: .:***** **:** * **.: *:. . :: * * ..: .:: : . : : . :::*.... . .:: .* .. **. .:*. . . : . : .: .*: **:* :* :.::*::*** :* . . :.: . : . :. *. *. : : . *:: * . :* : . :: .:. .. .... : ** * .* :. : .:::* . : .:* .: ** *: :: ***:*** . ::* * . .: .* : * :: * : .. : ::***..*:.**: * * *.* :: ", "identical_positions": 133, "similar_positions": 241, "identity": "18.12%" }, { "cls_id": "homologset.agr.SGD:S000005502", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TQK4-1", "uniprot_id": "EXOS3_MOUSE", "id": "Q7TQK4-1", "name": "Exosome complex component RRP40", "aln": "-----MAEVLSAGPESVAGCRARAVHKVLNQVVLPGEELVLPDHEDVDGLGGAGEQPLRLNAGARPRLRVVCGPGLRRCGDRLLVTKCGRLRHKEPSGGGGG---------VYWVDSQQK-----------------RYVPVKGDHVIGIVIAKSGDIFKVDVG-GSEPASLSYLAFEGATKRNRPNVQVGDLIYGQCVVANKDMEPEMVCIDSCGRANGMGVIGQDGLLFKVTLGLIRKLLAP-DCEIVQELGKLYPLEIVFGMNGRIWVKAKTIQQTLILAN-VLEACEHMTTEQRKQIFARLAES-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZT51-1", "uniprot_id": "D3ZT51_RAT", "id": "D3ZT51-1", "name": "Exosome complex component RRP40", "aln": "MVMPAMAEVS-AGAESVAGCRARAVHKVLNQVVLPGEELVLPDHEDADGLGGPGEQPLRLNAGARPRLRIVCGPGLRRCGDRLLVTKCGRLRHKEPSGGGGGGGGGGGGGGVYWVDSQQKRVSGCLRGGAAPKVGSLQYVPVKGDHVIGIVVAKSGDIFKVDVG-GSEPASLSYLAFEGATKRNRPNVQVGDLIYGQCVVANKDMEPEMVCIDSCGRANGMGVIGQDGLLFKVTLGLIRKLLAP-DCEIVQELGKLYPLEIVFGMNGRIWVKAKTIQQTLILAN-VLEACEHMTTEQRKQIFARLAES-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQT5-1", "uniprot_id": "EXOS3_HUMAN", "id": "Q9NQT5-1", "name": "Exosome complex component RRP40", "aln": "-----MAEPASVAAESLAGSRARAARTVLGQVVLPGEELLLPEQEDAEGPGGAVERPLSLNARACSRVRVVCGPGLRRCGDRLLVTKCGRLRHKEPGSGSGGG--------VYWVDSQQK-----------------RYVPVKGDHVIGIVTAKSGDIFKVDVG-GSEPASLSYLSFEGATKRNRPNVQVGDLIYGQFVVANKDMEPEMVCIDSCGRANGMGVIGQDGLLFKVTLGLIRKLLAP-DCEIIQEVGKLYPLEIVFGMNGRIWVKAKTIQQTLILAN-ILEACEHMTSDQRKQIFSRLAES-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IPX7-1", "uniprot_id": "EXOS3_DROME", "id": "Q8IPX7-1", "name": "Exosome complex component RRP40", "aln": "-------------------------MSATSTIVMPGERIAAIEELAKSK-------------------RVILGPGLRRLDDTVVASKAGPLRHKEPG--------------TFWVDNYQR-----------------RYIPARGDLILGIVRAKAGDLYRVDIG-ATDTASISYLAFEAASKKNRPDLIPGDLIYARVLNASADIEPELVCVNSVGKSGKLGVLT-DGFFFKCSLNLGRMLLRE-NCPVLAALTRELPYEIAVGVNGRIWLKAHSLKETVALAN-AISALEQSGCAEIDKICGNLGDFLQA----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08285-1", "uniprot_id": "RRP40_YEAST", "id": "Q08285-1", "name": "Exosome complex component RRP40", "aln": "----------------------------MSTFIFPGDSFPVDPTT-----------------------PVKLGPGIYCDPNTQEIRPVNTGVLHVSAKGKSG-------VQTAYIDYSSK-----------------RYIPSVNDFVIGVIIGTFSDSYKVSLQNFSSSVSLSYMAFPNASKKNRPTLQVGDLVYARVCTAEKELEAEIECFDSTTGRDAGFGILEDGMIIDVNLNFARQLLFNNDFPLLKVLAAHTKFEVAIGLNGKIWVKCEELSNTLACYRTIMECCQKNDTAAFKDIAKRQFKEILTVKEE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .::**: : : ***: : . : .. . ::* .: :*:* .* ::*:: .. .* ::*.: :...*:**::* *:*:*** : ***:*.: *. ::*.*: *.:* . : **:::. .*.: * ** : :: : *:..*:**:**:*.. :.:*: . :.. :: ..* . . ", "identical_positions": 45, "similar_positions": 87, "identity": "14.29%" }, { "cls_id": "homologset.agr.SGD:S000005505", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V897-1", "uniprot_id": "G3V897_RAT", "id": "G3V897-1", "name": "RNA polymerase-associated protein CTR9 homolog", "aln": "-------------MSRGSIEIPLRDTDEVIELDFDQLPEGD--EVISILKQEHTQLHIWIALALEYYKQGKTEEFVKLLEAARIDGNLDYRDHEKDQMTCLDTLAAYYVQQARKEKNKDNKKDLITQATLLYTMADKIIMYDQNHLLG-RACFCLLEGDKMDQADAQFHFVLNQSPN--------NIPALLGKACISFNKKDYRGALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLELNNKEA---------DSIKNGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKVQHLALH---AFHNTEVEAMQAESCYQLARSFHVQEDYDQAFQYYYQATQFASSSFVLPFFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAASEDQEK-------------RDIAKGHLKKVTE--QYPDD----VEAWIELAQILEQTDIQGALSAYGTATRILQEKVQADVPPEILNNVGALHFRLGNLGEAKKYFLASLDRAKAEAEHDEHYYNAISVTTSYNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLR--LGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQK--KFERILKQPATQSDTYSMLALGNVWLQTLHQPTRDR--EKEKRHQD---RALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYK-HQNTEVVLYLARALFK--------------CGKLQECKQTLLKARHVAPSDTVLMFNVALVLQRLATSVLKDEKSNLKEVLNAVKELELAHRYFSYLSKVGDKMRFDLALAASEARQCSDLLSQAQYHVARAR-KQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKKRKGSGSEQEGEEEEGGERKKKRRRRPPKGEEGSDDDETENGPKPKKRRPPRAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNS--DSDDDERPNRRASSESDSDDNQNKSGSEAGSPRRSGRQESDEDSDSDQPSRKRRRSGSEQSDNESAQSGRSPSGGSENENDSRPVSPSAESDHESEQGSDNEGSGQGSGNESEPEGSNNEASDRGSEHGSDDSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62018-1", "uniprot_id": "CTR9_MOUSE", "id": "Q62018-1", "name": "RNA polymerase-associated protein CTR9 homolog", "aln": "-------------MSRGSIEIPLRDTDEVIELDFDQLPEGD--EVISILKQEHTQLHIWIALALEYYKQGKTEEFVKLLEAARIDGNLDYRDHEKDQMTCLDTLAAYYVQQARKEKNKDNKKDLITQATLLYTMADKIIMYDQNHLLG-RACFCLLEGDKMDQADAQFHFVLNQSPN--------NIPALLGKACISFNKKDYRGALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLELNNKEA---------DSIKNGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKVQHLALH---AFHNTEVEAMQAESCYQLARSFHVQEDYDQAFQYYYQATQFASSSFVLPFFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAASEDQEK-------------RDIAKGHLKKVTE--QYPDD----VEAWIELAQILEQTDIQGALSAYGTATRILQEKVQADVPPEILNNVGALHFRLGNLGEAKKYFLASLDRAKAEAEHDEHYYNAISVTTSYNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLR--LGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQK--KFERILKQPATQSDTYSMLALGNVWLQTLHQPTRDR--EKEKRHQD---RALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYK-HQNTEVVLYLARALFK--------------CGKLQECKQTLLKARHVAPSDTVLMFNVALVLQRLATSVLKDEKSNLKEVLNAVKELELAHRYFSYLSKVGDKMRFDLALAASEARQCSDLLSQAQYHVARAR-KQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPVSKKKKRRKGSGSEQEGEEEEGGERKKKRRRRPPKGEEGSEEEETENGPKPKKRRPPRAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNS--DSDDDERPNRRASSESDSDDNQNKSGSEAGSPRRSGRQESDEDSDSDQPSRKRRRSGSEQSDNESVQSGRSPSGASENENDSRPASPSAESDHESEQGSDNEGSGQGSGNESEPEGSNNEASDRGSEHGSDDSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PD62-1", "uniprot_id": "CTR9_HUMAN", "id": "Q6PD62-1", "name": "RNA polymerase-associated protein CTR9 homolog", "aln": "-------------MSRGSIEIPLRDTDEVIELDFDQLPEGD--EVISILKQEHTQLHIWIALALEYYKQGKTEEFVKLLEAARIDGNLDYRDHEKDQMTCLDTLAAYYVQQARKEKNKDNKKDLITQATLLYTMADKIIMYDQNHLLG-RACFCLLEGDKMDQADAQFHFVLNQSPN--------NIPALLGKACISFNKKDYRGALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLELNNKEA---------DSIKNGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKVQHLALH---AFHNTEVEAMQAESCYQLARSFHVQEDYDQAFQYYYQATQFASSSFVLPFFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAASEDQEK-------------RDIAKGHLKKVTE--QYPDD----VEAWIELAQILEQTDIQGALSAYGTATRILQEKVQADVPPEILNNVGALHFRLGNLGEAKKYFLASLDRAKAEAEHDEHYYNAISVTTSYNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLR--LGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQK--KFERILKQPSTQSDTYSMLALGNVWLQTLHQPTRDR--EKEKRHQD---RALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYK-HQNTEVVLYLARALFK--------------CGKLQECKQTLLKARHVAPSDTVLMFNVALVLQRLATSVLKDEKSNLKEVLNAVKELELAHRYFSYLSKVGDKMRFDLALAATEARQCSDLLSQAQYHVARAR-KQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSEN--DSRPASPSAESDHESERGSDNEGSGQGSGNESEPEGSNNEASDRGSEHGSDDSD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1T9-1", "uniprot_id": "Q9W1T9_DROME", "id": "Q9W1T9-1", "name": "", "aln": "---------------------------------------------------MEKMLSTYIEEAMEFYAIGKGADFKAIIEKGIASCMTTYSTYDRELYKAYALLATYLSNHAFKIIK--SRPAFQAMAINCFDQLDSLRQQHDPHLQVTKGFLWMLSSSRAQDADALLISVLRNHPK--------NILALIGRACLAYNRQDYIGALGYFKSVLLIQPQGMADVWVGIGHCFWKMGELEKAQLSFQIALEHNGQCLNAALALALVKFEHNDE---------QSYQDGKMLLTAAYKENNKNPDLLSILAGMYYADGNHKLVWSFAGN---AIKFTANKHIESRNYFQIAKSYHATGQFESAKKYYLLSAKSAPDGYILPLVGVAQMYLHEGELNRSKAFLESFLTSEPDEPVVMDLLAKIYLEYKCPEK-------------IDKAIEMLVKVVESASYHQN----TNSWLNLAFAYEQKRLWAHGVNAYQKAIDIYLSQGHQIPIEWLNNLASSQLMAKMPEKALNTLDDALSKCRVMNSDNKTTN---LLSLQYNRGLVLEELHMFTLAAENYKSITKEYSSYHDCYLR--LGVMAIQKNNHTQAIEHLKDILVEDNLNMTARTYMGDCFKGLSLDKFATF--NYNMILARQSKFTNTYVSMAMGNFCLEKLQNWIAEGNFRAARKQQE---KALQCFGKILDCNPKNLWAANGIGAVLSSCNNLSAGGAIFKQIIECGNKCIPAIINSAHIALVSGQYRLAIQTYERCLKDHLP-KNRVDVMHCLAKALYD--------------NGDARKAKMWLLKVRHLVPHDPFVIFNLGLAIKKETEQALALPRPQLDELMGLDGLLKVAFKLFCHINLN--HPKISVRVSAKYAEDCQNLMTELIAKKRQAS-ESHAMEEDRVQLQKQRYRDHIEHQRQQELQREEEERVRRENLKIQRKEVLERTRKIISAPLAPDVPK-KSAGNGRAKKNQENG------------------------------DGKAKKSGPPKKKTRKR----AAGKEQEDIEPLKKPK---------------------------SKEFIDTDDDNSE---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P89105-1", "uniprot_id": "CTR9_YEAST", "id": "P89105-1", "name": "RNA polymerase-associated protein CTR9", "aln": "MTNAMKVEGYPSMEWPTSLDIPLKASEELVGIDLETDLPDDPTDLKTLLVEENSEKEHWLTIALAYCNHGKTNEGIKLIEMALD----VFQNSERASLHTFLTWAHLNLAKGQSLSVETKEHELTQAELNLKDAIGFDPTWIGNMLATVELYYQRGHYDKALETSDLFVKSIHAEDHRSGRQSKPNCLFLLLRAKLLYQKKNYMASLKIFQELLVINPVLQPDPRIGIGLCFWQLKDSKMAIKSWQRALQLNPKNTSASILVLLGEFRESFTNSTNDKTFKEAFTKALSDLNNIFSENQHNPVLLTLLQTYYYFKGDYQTVLDIYHHRILKMSPMIAKIVLSESSFWCGRAHYALGDYRKSFIMFQESLKKNED-NLLAKLGLGQTQIKNNLLEESIITFENLYKTNESLQELNYILGMLYAGKAFDAKTAKNTSAKEQSNLNEKALKYLERYLKLTLATKNQLVISRAYLVISQLYELQNQYKTSLDYLSKALEEMEFIKKEIPLEVLNNLACYHFINGDFIKADDLFKQAKAKVSDKDES-------VNITLEYNIARTNEKN-DCEKSESIYSQVTSLHPAYIAARIRNLYLKFAQSKIEDSDMSTEMNKLLDLNKSDLEIRSFYGWYLKNSKERKNNEKSTTHNKETLVKYNSHDAYALISLANLYVTIARDGKKSRNPKEQEKSKHSYLKAIQLYQKVLQVDPFNIFAAQGLAIIFAESKRLGPALEILRKVRDS-LDNEDVQLNLAHCYLEMREYGKAIENYELVLKKFDNEKTRPHILNLLGRAWYARAIKERSVNFYQKALENAKTALDLFVKESSKSKFIHSVKFNIALLHFQIAETLRR-SNPKFRTVQQIKDSLEGLKEGLELFRELNDLKEFNMIPKEELEQRIQLGETTMKSALERSLNEQEEFEKEQSAKIDEARKILEENELKEQGWMKQEEEARRLKLEKQAEEYRKLQDEAQKLIQEREAMAISEHNVKDDSDLSDKD----------------NEYDEEKPRQKRKRSTKTKNSGESKRRKAAKKTLSDSDEDDDDVVKKPSHNKGKKSQ--------------------LSNEFIEDSDEEEAQMSGSEQNKNDDNDENNDNDDNDGLF-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :: *: : ** : ::* . : :: * :. . .. : . * . .: ::. : :. : * *: :* : :::::* .:* ::. * :* .: :*:* ** :: . : * ::. **: * : .* : : : ::... :: .. *. :. : ** :*. * :: . ::. * : : : : : :.. : .::.:. :: .: : : : . :*. .*:.* : .. :.: :*.. .: . :*. :* * : * * : : .: .::: :: * : ::* * ***:.. :: :* . : : : . :: .** . * : . *..: :. * . :* :* .* : : ::. * :: . : * . ..: . ::* :::.*. : :: . . .: :. :*: : ::* :. *::**:*:. ::: : . :: :: :. . . :* ** : :* *:: ** *:.. : . .:: *.:* : . : . ::* : **:.* : : ..:: : *: . : : .:.: . . : :: :.. *.: .: . :: ::: . .*. .: :* * : : : :. .. . .. . . : ::.* *:: : ..:::: . : *: :*. .*:.. ", "identical_positions": 86, "similar_positions": 317, "identity": "6.85%" }, { "cls_id": "homologset.agr.SGD:S000005506", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z9I4-1", "uniprot_id": "D3Z9I4_RAT", "id": "D3Z9I4-1", "name": "DNA replication complex GINS protein PSF3", "aln": "MSEAYFPVESGALGPEENFLSLDDIVMSQEKLPVRVETPMPRLGAFFLERGAGAEADHPLPQGTKLELPLWLAKGLFDNKR----------RILSVELPKMYQEGWRTVFSADANVVDLHKMGPHFYGFGSQLLHFDSPENSDISQSLLQTFIGRFRRIMDSSQNSYNEDTSALVARLDETERGLFQIGQKGLNDFQSWEKGQASQITASSLVQNYKK-RKFTNLED--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CY94-1", "uniprot_id": "PSF3_MOUSE", "id": "Q9CY94-1", "name": "DNA replication complex GINS protein PSF3", "aln": "MSEAYFPVESGALGPEENFLSLDDILMSQEKLPVRVETPMPRLGAFFLERGAGSEPDHPLPQGTKLELPLWLAKGLFDHKR----------RILSVELPKMYQEGWRTVFSADANVVDLHKMGPHFYGFGSQLLHFDSPENADISQSLLKTFIGRFRRIMDSSQNSYNEDTSALVARLDETERGLFQIGQRSLNDFQSWEKGQASQITASSLVQNYKK-RKFTNMED--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BRX5-1", "uniprot_id": "PSF3_HUMAN", "id": "Q9BRX5-1", "name": "DNA replication complex GINS protein PSF3", "aln": "MSEAYFRVESGALGPEENFLSLDDILMSHEKLPVRTETAMPRLGAFFLERSAGAETDNAVPQGSKLELPLWLAKGLFDNKR----------RILSVELPKIYQEGWRTVFSADPNVVDLHKMGPHFYGFGSQLLHFDSPENADISQSLLQTFIGRFRRIMDSSQNAYNEDTSALVARLDEMERGLFQTGQKGLNDFQCWEKGQASQITASNLVQNYKK-RKFTDMED--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W2V7-1", "uniprot_id": "Q9W2V7_DROME", "id": "Q9W2V7-1", "name": "DNA replication complex GINS protein PSF3", "aln": "---------MNGMNYFPNYYSIEDIFVTQEKVECRVNTKLQRMG--FLDSGAESDD---LEPGRTVNLPLWYIKELKVNN-----------AYFTVAVPDIYRNVHKAVCEAETTHIELGRLHPYFYEFGRYLTPYDR--NHVIGRIIFETLRQRVRHLLDISKS--DGQAAKAEHRLDNIEAKLHEAGVRTNSQYIEWLQMTGNKIRTSELVEEHQKKRRRADRSDDEGDALPNSKRATL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12146-1", "uniprot_id": "PSF3_YEAST", "id": "Q12146-1", "name": "DNA replication complex GINS protein PSF3", "aln": "----------------MGYYDIDDVLADGTEFPCKFQYDIPGLG--YLEN----NPGRPITKNTKLSLPLWLARILAIVGGDEALVDEEPVPFVELLPPDMFSTKVMNAIKTDPVALDLHSINSHFFSLAIKWIMLFS--EKELANVVSELLLQRAQELN--------HHASSLSIDLNADSTGKNSANTNIATSTFLLKLEEMEKEIYKKSHESYKDTKRWMFKK---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .::*:. :. : : : :* :*: : : . .:.**** : * . : *.:: . .::. ::* : .:*: :. : :.. : : : * :.: .:: *: . . . . .. .: .. :.::. :: . ", "identical_positions": 13, "similar_positions": 72, "identity": "5.39%" }, { "cls_id": "homologset.agr.SGD:S000005507", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70597-1", "uniprot_id": "PX11A_RAT", "id": "O70597-1", "name": "Peroxisomal membrane protein 11A", "aln": "-----------MDAFIRVANQSQGRDRLFRATQHACMLLRYLLESKAGKEAVVTKLKNLETSVSTGRKWFRLGNVLHAIQATEQSIQ---ATDLVPRLCLTLANLNRVVYYICDTVLWAKSVGLTSG--INREKWQMRAARHYYYFLLLSLVRDLYEVLLHMGQVARDRAKREKSS-------------GDPPKYS-VANEESEWLQSFLLLLFQSLKRNPPLFLDTVKNFCDILIPLNQLGIYKSNLGVVGFGGLVSSVAGLITVVYPQLKLKAR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z211-1", "uniprot_id": "PX11A_MOUSE", "id": "Q9Z211-1", "name": "Peroxisomal membrane protein 11A", "aln": "-----------MDAFIRVANQSQGRDRLFRATQHACMLLRYLLESKADKEAVVLKLKRLETSVSTGRKWFRLGNVFHAIQATEQSIQ---AADLAPRLCLTLANLNRVVYYICDTVLWAKSVGLTSG--VNREKWQRWAARHYYYFLLLSLVRDLYEILLQMGQVARDRAKREKSS-------------RDPPKYS-VANEETEWLQSFLLLLFQSLKRHPPLLLDTVKNFCDILIPLNQLGIYKSNLGVVGLGGLISSLAGLLTVVYPQLKLKAR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75192-1", "uniprot_id": "PX11A_HUMAN", "id": "O75192-1", "name": "Peroxisomal membrane protein 11A", "aln": "-----------MDAFTRFTNQTQGRDRLFRATQYTCMLLRYLLEPKAGKEKVVMKLKKLESSVSTGRKWFRLGNVVHAIQATEQSIH---ATDLVPRLCLTLANLNRVIYFICDTILWVRSVGLTSG--INKEKWRTRAAHHYYYSLLLSLVRDLYEISLQMKRVTCDRAKKEKSAS------------QDPLWFS-VAEEETEWLQSFLLLLFRSLKQHPPLLLDTVKNLCDILNPLDQLGIYKSNPGIIGLGGLVSSIAGMITVAYPQMKLKTR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z210-1", "uniprot_id": "PX11B_MOUSE", "id": "Q9Z210-1", "name": "Peroxisomal membrane protein 11B", "aln": "-----------MDAWVRFSAQSQARERLCRAAQYACSLLGHALQRHGASPELQKQIRQLEGHLSLGRKLLRLGNSTDALESAKRAVH---LSDVVLRFCITVSHLNRALYFACDNVLWAGKSGLAPR--VDQEKWAQRSFRYYLFSLIMNLSRDAYEIRLLMEQETSAYSRRMKVSGVGVSGGVETVGPGGPGTPGGSLPQLALKFRLRILLLARVLRGHPPLLLDVLRNACDLFIPLDKLGLWRCGPGIVGLCGLISSILSILTLICPWLRLKP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FA09-1", "uniprot_id": "F7FA09_RAT", "id": "F7FA09-1", "name": "", "aln": "-----------MDAWVRFSAQSQARERLCRAAQYACSLLGHALQRHGASPELQKQIRQLEGHLSLGRKLLRLGNSADALESAKRAVH---LSDVVLRFCITVSHLNRALYFACDNVLWAGKSGLAPR--VDQEKWAQRSFRYYLFSLIMNLSRDAYEIRLLMEQETSAHSRRMKISGVGVSG-LETGGPGGPGTPGGCLPQLALKFRLRILLLARVLRDHPPLLLDVLRNACDLFIPLDKLGLWRCGPGIVGLCGLISSVLSILTLICPWLRLKP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O96011-1", "uniprot_id": "PX11B_HUMAN", "id": "O96011-1", "name": "Peroxisomal membrane protein 11B", "aln": "-----------MDAWVRFSAQSQARERLCRAAQYACSLLGHALQRHGASPELQKQIRQLESHLSLGRKLLRLGNSADALESAKRAVH---LSDVVLRFCITVSHLNRALYFACDNVLWAGKSGLAPR--VDQEKWAQRSFRYYLFSLIMNLSRDAYEIRLLMEQESSACSRRLKGSGGGVPGGSETGGLGGPGTPGGGLPQLALKLRLQVLLLARVLRGHPPLLLDVVRNACDLFIPLDKLGLWRCGPGIVGLCGLVSSILSILTLIYPWLRLKP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12462-1", "uniprot_id": "PEX11_YEAST", "id": "Q12462-1", "name": "Peroxisomal membrane protein PMP27", "aln": "MVCDTLVYHPSVTRFVKFLDGSAGREKVLRLLQYLARFL--------AVQNSSLLARQLQAQFTTVRKFLRFLKPLNHLQAAAKFYDNKLASDNVVRVCNVLKNIFFAAYLSLDQVNLLRILKVIPVTVLTGKKIPRWSNWCWLFGLLSGLAMDLRKIQTSHAQIAAFVKAKSQSQG--------------------------DEHEDHKKVLGKAYQDRYTALRRLFWDAADSFIVLNNLGYLSSNEEYVALSGVVTSILGMQDMWKAT------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :. : .*::: * *: . :* :.*: .: ** :*: : . :::: : . :* . *.* .: :: . * * : : . : :* : : : *: .* * :: : : : : . :* : : . . : . : .* : *::** .. :.: *:::*: .: : . ", "identical_positions": 24, "similar_positions": 77, "identity": "8.7%" }, { "cls_id": "homologset.agr.SGD:S000005509", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AE80-1", "uniprot_id": "D4AE80_RAT", "id": "D4AE80-1", "name": "5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase", "aln": "MALSCSPVRPRPRGSAWRSKMELLSRAEQEMSLAALKQHDPYITSIADLTGQVALYTFCPKANQWEKTDIEGTLFVYRRSASPYHGFTIVNRLNMHNLVEPVNKDLEFQLHEPFLLYRNASLSIYSIWFYDKNDCHRIAKLMADVVEEEARRAQQAARDKQSPSQANGCSDQRPIDILEMLSRAKDEYERNQ-MGGSNISSPGLQPSSQLSNLGSTETLEETPSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAPMGLESEDTDKLLGDAPQKEPS------SFLPFPFEQSGGAPQAENLGVHSVTHHTVQPEVSAPVLITPASIAQSGDKHPPSYTLPLSPVLSPTLPAEAPTTQVP-HLPRNSTMMQAVRTTPRQKSPLLNQPVPELSHSSLIAS-QSPFRAPVSLANTAGTAIPSSDLLQKLRLTPQHDQIQAQPLGKGAMAPNFSSAAGQLATPESFIEPSSKTAAARAAVAASLSNMVLAPTLQSMQQNQDPEVFAQPKVLPSAIPIAGPPLVTATTTAVSSVLLSPSVF------------------------------------QQTVPRSADLERKASCPSPLTIG-AENQRKPSIILSRSQLQDTLIHLIKNDSGFLSTLHEVYLQVLTKSKDNHSL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YD3-1", "uniprot_id": "DCP1A_MOUSE", "id": "Q91YD3-1", "name": "mRNA-decapping enzyme 1A", "aln": "MALSCSTVRPRRRGSALRSKMELLSRAEQEMSLAALKQHDPYITSIADLTGQVALYTFCPKANQWEKTDIEGTLFVYRRSASPYHGFTIVNRLNMHNLVEPVNKDLEFQLHEPFLLYRNASLSIYSIWFYDKNDCHRIAKLMADVVEEETRRSQQAARDKQSPSQANGCSDQRPIDILEMLSRAKDEYERNQ-MGGSNISSPGLQPSTQLSNLGSTETLEETPSGSQDKSAPSGHKHLTVEELFGTSLPKEQPTAMGLESEDTDKLLGDASQKEPS------SFLPFPFEQSGGAPQSENLGIHSAAHHTVQPEVSTPVLITPASIAQSGDKHPPSYTLPLSPVLSPTLPAEAPTTQVP-HLPRNSTMIQAVKTTPRQKSPLLNQPVPELSHSSLVAS-QSPFRAPVSLANPAGTALPSVDLLQKLRLTPQHDQIQAQPLGKGTMAPSFSSAAGQLATPESFIEPSSKTAAARAAVSASLSNMVLAPTLQSMQQNQDPEVFSQPKVLPSAIPIAGSPLVPATTTAVSSVLLSPSVF------------------------------------QQTVPRAADLERKASSPSPLTVGTAESQRKPSIILSKSQLQDTLIHLIKNDSSFLSTLHAVYLQVLTKNKDNHNL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPI6-1", "uniprot_id": "DCP1A_HUMAN", "id": "Q9NPI6-1", "name": "mRNA-decapping enzyme 1A", "aln": "--------------------MEALSRAGQEMSLAALKQHDPYITSIADLTGQVALYTFCPKANQWEKTDIEGTLFVYRRSASPYHGFTIVNRLNMHNLVEPVNKDLEFQLHEPFLLYRNASLSIYSIWFYDKNDCHRIAKLMADVVEEETRRSQQAARDKQSPSQANGCSDHRPIDILEMLSRAKDEYERNQ-MGDSNISSPGLQPSTQLSNLGSTETLEEMPSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSEEMERLPGDASQKEPN------SFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIAN-QSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAP-LQSMQQNQDPEVFVQPKVLSSAIPVAGAPLVTATTTAVSSVLLAPSVF------------------------------------QQTVTRSSDLERKASSPSPLTIGTPESQRKPSIILSKSQLQDTLIHLIKNDSSFLSTLHEVYLQVLTKNKDNHNL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3U564-1", "uniprot_id": "DCP1B_MOUSE", "id": "Q3U564-1", "name": "mRNA-decapping enzyme 1B", "aln": "---------------MAAAAAGGLPGKGHDISLAALRRHDPYISRIVDVASQVALYTFGHRANEWEKTGVEGTLFVYTRSASPKHGFTIMNRLSMENRTEPITKDLDFQLQNPFLLYRNGTLSIYGIWFYDKEECQRIAKLMKNLTQSEQLKACH--GAGSSP-VTLSSGEGQEVDILQMLTKAKDEYTKCKTCSEPKQMTNSSAICDN-PKLIKPVPVRPSSSQRLQGPAPSKTSDPEPQHLSLTALFGKQDKAPCQETVKPSRTFAHHHHHHHQ-QQQETRPVHHGVACSLSCEEPRKLS----LPVEKQLCPAIQKLMLGSPGLHPLPQHPEQWSCKSGSPSPAGGILPGPVQLGSPWNGRVAHCTQSTCRGHKLLEQLQGAPGAVHKYNPCAPT-----------GPAVATQVAPGQSVAQSQLVYFSGPLQPPAPGHQALRKEQGALPAQAVSLSGSQ-ESS---PTVLPTQELLRKLQVVHQEQ--QAAPRPALAARFPVSAQGSGTEKPLEAWVSKTASMEKQAP---LLQS------------------------TCAPLRETDNGLMALGGQELPAASSNLLLPLQNWESSTVASRPLTRLQLQEALLNLIQNDDNFLSIIYEAYLFSVTQAAMRTT----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZZJ7-1", "uniprot_id": "D3ZZJ7_RAT", "id": "D3ZZJ7-1", "name": "5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase", "aln": "---------------MAAAAAGGLPGKGHDISLAALRRHDPYINRIVDVASQVALYTFGHRANEWEKTGVEGTLFVYTRSASPKHGFTIMNRLSMENRTEPITKDLDFQLQDPFLLYRNGTLSIYGIWFYDKEECQRIAKLMKNLTQCEQLKACHGAGAGSSP-VTLSSGEGREVDILQMLTKAKDEYTKCRSCSEPKQMTSSSAICDN-PKLIKPVPVRPSSSQRLHEPTPSKTLDPEPQHLPLTALFGKQDKAPCQETVKPSRTFAHHHHHHHHHQQQEKLPVHHGVACSLACEDPRKLS----LPVEKQLCPAIQKLMVGSMGLHSLPQHPGQWPCESGSPSPAGGILPGPVQLGAPWNGRAAHCTQSTCRSHKLLEQLQGAPAAVHKYSFCAPA-----------SPAVTTQVAPGQSVAQSQLVYFSGPLPPPTPGHQALGKEQCAPPAQAVSLSGSQ-ESS---PTVLPTQELLRKLQVVQQEQ--QAAPRPALAARFPVSAQGSGTEKPLEAWVSKTASMEKQAP---LLQS------------------------TCAPLRETDNGLMALGGPELPAASSSLLLPLQNWESSTMASRPLTRLQLQEALLNLIQNDDNFLSIIYEAYLFSVTQAAMRKAT---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IZD4-1", "uniprot_id": "DCP1B_HUMAN", "id": "Q8IZD4-1", "name": "mRNA-decapping enzyme 1B", "aln": "---------------MAAVAAGGLVGKGRDISLAALQRHDPYINRIVDVASQVALYTFGHRANEWEKTDVEGTLFVYTRSASPKHGFTIMNRLSMENRTEPITKDLDFQLQDPFLLYRNARLSIYGIWFYDKEECQRIAELMKNLTQYEQLKAHQGTGAGISP-VILNSGEGKEVDILRMLIKAKDEYTKCKTCSEPKKITSSSAIYDN-PNLIKPIPVKPSENQQQRIPQPNQTLDPEPQHLSLTALFGKQDKATCQETVEPPQTLHQQQQQQQQ--QQEKLPIRQGVVRSLSYEEPRRHS----PPIEKQLCPAIQKLMVRSADLHPLSELPENRPCENGSTHSAGEFFTGPVQPGSPHNIGTSRGVQNASRTQNLFEKLQSTPGAANKCDPSTPAPASSAALNRSRAPTSVTPVAPGKGLAQPPQAYFNGSLPPQTVGHQAHGREQSTLPRQTLPISGSQ-TGS---SGVISPQELLKKLQIVQQEQQLHASNRPALAAKFPVLAQSSGTGKPLESWINKTPNTEQQTP---LFQVISPQRIPATAAPSLLMSPMVFAQPTSVPPKERESGLLPVGGQEPPAAATSLLLPIQSPEPSVITSSPLTKLQLQEALLYLIQNDDNFLNIIYEAYLFSMTQAAMKKTM---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q0R5-1", "uniprot_id": "A0A8M9Q0R5_DANRE", "id": "A0A8M9Q0R5-1", "name": "5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase", "aln": "---------------MTASTGGG--GSCLSMSLSALKRLDPYISSITDLASQVALYTFNNNTNEWEKTNVEGTLFVYSRLASPRHGFTILNRLSMDNLTEPITKDLDFQLQHPFLLYRNARLSIYGIWFYDKEDCQRIAELMKNLAGQEQQLQAQIATGCLSP-RSAEQG----VDIMQMLTKARNDYDKGK-LSEPKEIGSGGIIYGQTPHLIKPIPLKPAQDTHIQAHT-QHDAEMDSKHLSVVTLFGAQPK-PDLGSTQPSLSVGRMG------------PARSSVARSLSYDDPSPAGGAVVSSTPMQHCPAIHKLMSGSL-LQPLSESPESRLCENG----AVQIQPDPIQ-----------------------KLLMNPP------------------------PVAGTTVMPSIQLKQGEVG--------MGPQIHSMAKPSGPFPAQHLFVPNKV-PSAGVTSNVVSPHELLQKLTLVQQEQ--------ELHPQQEVLQPGLTTSS---SNLSKTNLTQVMSP---QRIP------------------------------------ATVAPTLLLSPSVFAQTKVTRADPEPVESRALSKSQLQATLLHLIKNDASFLDTIYEAYISRLTTDSSSKPF---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1H5-1", "uniprot_id": "Q9W1H5_DROME", "id": "Q9W1H5-1", "name": "", "aln": "----------------------MADESITRMNLAAIKKIDPYAKEIVDSSSHVAFYTFNSSQNEWEKTDVEGAFFIYHRNAEPFHSIFINNRLNTTSFVEPITGSLELQSQPPFLLYRNERSRIRGFWFYNSEECDRISGLVNGLLKSKDQGTNGQAQRHVSAPQQPKQDSSQPASIFNMLTKAQKDYNAQVSGGQPKTPSAENVTAGNVLKFFESAKQATAES-----------LFHRVQPLSVDQLEKQQRAATPGEDLLP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PAGRDNHESRLSPFQKMQQLN--------------------IQLLSDLKIGKSYATAQSPTVAPSSSALMANDDAGKCLRRLLAGDKPGPALMP--------------------------------------------------PTMFDAPNNGNPEPQQPQQPQQPLLNSTQFVQAFTYLIQNDKEFANKLHKAYLNGCSNLLLDSSSTYQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12517-1", "uniprot_id": "DCP1_YEAST", "id": "Q12517-1", "name": "mRNA-decapping enzyme subunit 1", "aln": "---------MTGAATAAENSATQLEFYRKALNFNVIGRYDPKIKQLLFHTPHASLYKWDFKKDEWNKLEYQGVLAIYLRDVSQNTNLLPVSPQEVD-IFDSQNGSNNIQVNN------------------GSDNSNRNSSGNGNSYKSND----------------------------------SLTYNCGKTLSGKDIYNYGLIILNR----------------------------INPDNFSMGIVPN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVVNKRKVFNAEEDTLNPLECMGVEVKDELVIIK------------------------------------------------------------NLKHEVYGIWIHTVSDRQNIYELIKYLLENEP------KDSFA---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: .: : ** . : : :.::*.: ::*:* :*.: :* * .. .: . . :. . . ::* : ..::..* : . : * . . . . : : : . :: : *::*: : ", "identical_positions": 13, "similar_positions": 59, "identity": "2.0%" }, { "cls_id": "homologset.agr.SGD:S000005511", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V762-1", "uniprot_id": "G3V762_RAT", "id": "G3V762-1", "name": "GDP-L-fucose synthase", "aln": "-----MGEP----HGSMRILVTGGSGLVGRAIQKVVADG-AGLPGEEWVFVSSKDADLTDAAQTQALFQKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHINDNVLHSAFEVGTRKVVSCLSTCIFPDKTTYPIDETMIHNGPPHSSNFGYSYAKRMIDVQNRCS-LLVLPRPLWRGEDGPLGPTSSSMAVPSPLSSLPMSLGLTTTSTSKMATCCRASSIRCTWPRVSAAVRHAPGPGSGSALTVWGTGKPRRQFIYSLDLARLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFS-GEVTFDSTKSDGQYKKTAS--NGKLRSYLPDFCFTPFKQAVKETCAWFTENYEQARK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12068-1", "uniprot_id": "GRE2_YEAST", "id": "Q12068-1", "name": "NADPH-dependent methylglyoxal reductase GRE2", "aln": "MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSP-------------EDKIPELFGG------YIDVRDVAKAHLVAFQKRETIGQRLIVS--EARFTMQDVLDILNEDFPVLKGNIPVGKPGSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEGRI--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : :*:. . ::* * .: *:. : *:: * . .*::. : :*** * * : * . : *: *: ..:*** : .: .* : *. :. . :: . .* * . : : *: *. . :. *. : .... .::. .*: : .: . ... ::* ..*: * ... ::* :* *:*: .: .::: : : :: * ..::::. : : * : . *::..... *.. ::. .: :.* . * .* * :*:::.:*.: : : : ", "identical_positions": 44, "similar_positions": 133, "identity": "12.05%" }, { "cls_id": "homologset.agr.SGD:S000005512", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CIZ9-1", "uniprot_id": "NOX1_MOUSE", "id": "Q8CIZ9-1", "name": "NADPH oxidase 1", "aln": "MAGELRGSRGPLQRIQIAPREAPNLHLTMGNWLVNHWLSVLFLVSWLGLNIFLFVYAFLNYEKSDKYYYTREILGTALALARASALCLNFNSMMILIPVCRNLLSFLRGTCSFCNRTLRKPLDHNLTFHKLVAYMICIFTVIHIIAHLFN-FERYRRSQQAMDGSLASVLSSLSHP-EKED-SWLNPIQSPNMTVMYAAFTSIAGLTGVIATVALVLMVTSAMEFIRRNY---FELFWYTHHLFIVYIICLGIHGLGGIVRGQTEESLGESHPHNCSHSFHEWDDHKGSCRHPHFAGHPPESWKWILAPIAFYIFERILRFYRSQQKVVITKVVMHPSNVLELQMRKRGFSMEVGQYIFVNCPSISFLEWHPFTLTSAPEEEFFSVHIRAAGDWTRNLIRTFEQQHSPMPRIEVDGPFGTVSEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQRADNKLKTQKIYFYWICRETGAFAWFNNLLNSLEQEMEELGKMDFLNYRLFLTGWDSN--IAGHAALNFDRATD--ILTGLKQKTSFGR---------PMWDNEFSRIATAHP-----KSAVGVFLCGPRTLAKSLRKRCQRYSS------------LDPRKVQFYFNKETF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WV87-1", "uniprot_id": "NOX1_RAT", "id": "Q9WV87-1", "name": "NADPH oxidase 1", "aln": "----------------------------MGNWLVNHWLSVLFLVSWLGLNIFLFVYVFLNYEKSDKYYYTREILGTALALARASALCLNFNSMVILIPVCRNLLSFLRGTCSFCNHTLRKPLDHNLTFHKLVAYMICIFTAIHIIAHLFN-FERYSRSQQAMDGSLASVLSSLFHP-EKED-SWLNPIQSPNVTVMYAAFTSIAGLTGVVATVALVLMVTSAMEFIRRNY---FELFWYTHHLFIIYIICLGIHGLGGIVRGQTEESMSESHPRNCSYSFHEWDKYERSCRSPHFVGQPPESWKWILAPIAFYIFERILRFYRSRQKVVITKVVMHPCKVLELQMRKRGFTMGIGQYIFVNCPSISFLEWHPFTLTSAPEEEFFSIHIRAAGDWTENLIRTFEQQHSPMPRIEVDGPFGTVSEDVFQYEVAVLVGAGIGVTPFASFLKSIWYKFQRAHNKLKTQKIYFYWICRETGAFAWFNNLLNSLEQEMDELGKPDFLNYRLFLTGWDSN--IAGHAALNFDRATD--VLTGLKQKTSFGR---------PMWDNEFSRIATAHP-----KSVVGVFLCGPPTLAKSLRKCCRRYSS------------LDPRKVQFYFNKETF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5S8-1", "uniprot_id": "NOX1_HUMAN", "id": "Q9Y5S8-1", "name": "NADPH oxidase 1", "aln": "----------------------------MGNWVVNHWFSVLFLVVWLGLNVFLFVDAFLKYEKADKYYYTRKILGSTLACARASALCLNFNSTLILLPVCRNLLSFLRGTCSFCSRTLRKQLDHNLTFHKLVAYMICLHTAIHIIAHLFN-FDCYSRSRQATDGSLASILSSLSHD-EKKGGSWLNPIQSRNTTVEYVTFTSIAGLTGVIMTIALILMVTSATEFIRRSY---FEVFWYTHHLFIFYILGLGIHGIGGIVRGQTEESMNESHPRKCAESFEMWDDRDSHCRRPKFEGHPPESWKWILAPVILYICERILRFYRSQQKVVITKVVMHPSKVLELQMNKRGFSMEVGQYIFVNCPSISLLEWHPFTLTSAPEEDFFSIHIRAAGDWTENLIRAFEQQYSPIPRIEVDGPFGTASEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQCADHNLKTKKIYFYWICRETGAFSWFNNLLTSLEQEMEELGKVGFLNYRLFLTGWDSN--IVGHAALNFDKATD--IVTGLKQKTSFGR---------PMWDNEFSTIATSHP-----KSVVGVFLCGPRTLAKSLRKCCHRYSS------------LDPRKVQFYFNKENF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12333-1", "uniprot_id": "FRE7_YEAST", "id": "Q12333-1", "name": "Ferric/cupric reductase transmembrane component 7", "aln": "MIEERDLVLSNGIHCIADIHSELYARLKKESQAATPWVYQKQYGKFVTYFVAVIIFLSLIKKLAFMYYDSSEEFLPEKKNSPTTPSVFLARIMTKLVAFNRYICYRKFPTLIFSYLGIPTSVGTFLVVMATTLYTLLYCFVPHPFYRPCAGFGSPPLSVRAGIMAISLVPFVFSLSGKINVIGWLVGLSYEKINIYHQWASILCLFFSWVHVIPFLRQARHEGGYERMHQRWKASDMWRSGVPPILFLNLLWLSSLP-IARRHFYEIFLQLH-WILAVGFYISLFYHVYPELNSHMYLVATIVVWFAQLFYRLAVKGYLRPGRSFMASTIANVSIVGEGCVELIVKDVEMAYSPGQHIFVRTIDKGIISNHPFSIFPSAK---YPGGIKMLIRAQKGFSKRLYESNDDMKKILIDGPYGGIERDIRSFTNVYLICSGSGISTCLPFLQ----KYGPILHKTNLEVITLDWVVRHREDISWIRDEMCTLSNNLRQLFLDGKIVVRIYVCSDSTVPGIIKTFPQTIDTASDQSDLAKREKDTEFGQDDTESNSTFDKSNNEYKGLITIIPSKPDLNQVINDYQIGFRNCFICSGSDSLRYTVGNSVAGLQAKVFSNKNVEECYLHSESFGY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. *. :: : ::: * : : ** : : : . : ::. : . *:.. * : * *. : . :. *.. . * : . * : : * * :* ::: : : : : .** :. : .: : : :. : . : .:.:: . : * . :* : *.:: * : .: *.* : * : : * : .* . . . . *: . : ** ** .*::* : :** :.. :: **:***. . .::. ***:: .:.: :. *: ..: : : :. . : :* :***:* ..*: .: . *: :* *::. .:*: *: :: : : * : *: *. ::*:.: : :*.::: :* . : *::: . .: * . .:* *:* :: ::.*.**: :**:. : * * :..:. : * . . . . **: : . : *::.*.* ", "identical_positions": 78, "similar_positions": 201, "identity": "12.4%" }, { "cls_id": "homologset.agr.SGD:S000005516", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A9T2-1", "uniprot_id": "A0A8I6A9T2_RAT", "id": "A0A8I6A9T2-1", "name": "Solute carrier family 2, facilitated glucose transporter member 12", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLQSSLNSEYSPASQAKEQPDRR----------------SSVCSSLSEGPNLLNQKGREAETDGSCGASGGRHPACAGG----------------------------------------------------------------------------------------------------------------------------------------------PGMFTFLTSVTAAISGLLVGYELGLIS------GALLQIRTL-----LALTCHEQEMVVSSLLIGAFLASLTGGVLIDRYGRRLTIILSSCLLGLGSLVLILSLS-YTLLITGRVAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVTGILFAYISNYAFANIS--NGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEEAAGKVLRKLRVISDTAEELT-------LIKSSLKDEYQYSFWDLFRSKDNMRTRILIGLTLVFFVQTTGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVVSTIPATLLVDHVGSKTFLCIGSSVMAASLLTMGIVNLNINMNFTNICRSHSPLNQSLEELVFYATGNLSVSNSSLGEHLKRVTPYSKGLFIPLGNGMEPKGEMAFTSLPNAGLSRTDRQGVTDPAVVPAVYKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLSWVCFIYTVMSLTSLAFVVLFIPETKGCSLEQISMELSKANYVKNNICFMSHHQEELVPTQLQKTKPQEQLPECKKLCGRGQSQRPSPET", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZVY8-1", "uniprot_id": "D3ZVY8_RAT", "id": "D3ZVY8-1", "name": "Solute carrier family 2, facilitated glucose transporter member 10", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MILQTESLWDAETIGGSADSSKE----------------TPVMQTGLYTP----------EPSQLAGLGPTVLPLCAS---------------------------------------------------------------------------------------------------------------------------------------------------------VSLLGGLTFGYELAVIS------GALLPLQLD-----FGLSCLEQELLVGSLLLGAFLASLVGGFLIDCYGRRRAILGSNVVLLAGSLILGLAGS-LPWLLLGRSSVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEVGITVGILFSYGLNYVLAGRP--WGWRHMFGWAAAPALLQSLSLFFLPAG-------AEGTAARQDLIPLQ--GGETSKLG-------LVKA------QYTFLDLFRAQDGMWSRTVVGLGLVLFQQLTGQPNVLYYASTIFRSVGFHGGSSAVLASVGLGTVKVVATLIATGLVDRVGRRALLLSGCALMALSVSGIGLVSFAVSLDSGPSCLATS---NTSQQVDLPQTPGLLVRTS-----LPPVLHTSGDQGQPVRSVTERPIHPVITASLGPALN-IDSSVPTSPIPEHTLLCWSALVCMMVYVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCSSFNWAANLFISLSFLDLIGAIGLAWTFLLYGLTAVLGLAFIYLLVPETKGQSLAEIEQQFQMR---RFPLSFGHRQHSGIQYRRLEVSSAS----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LPG5-1", "uniprot_id": "A0ABK0LPG5_RAT", "id": "A0ABK0LPG5-1", "name": "Solute carrier family 2, facilitated glucose transporter member 6", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQEPLLRAEGLDYDTFPEAPASPEEKARAGA----------------------------------------------------------------------------------------------------------------------------------------------LQNRRVFLATFAAVLGNFSFGYALVYTS------PVIPALKRS-SDPALRLDKIQASWFGSVFTLGAAAGGLSAMLLNDLLGRKLSIMFSAVPSAIGYALMAGARG-LWMLLLGRMLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP-------WRWLAVAGEGPVLVMILLLSFMPNSPRFLLSKSRDEEALQALIWLRADSEVHWEFE--------QIQDNVRRQSSRVSWAEAWEPRVYRPILITVLMRFLQQLTGITPILVYLQTIFDSTSVV--LPSQQDAAIVGAVRLLSVLIAAVTMDLAGRKVLLYVSASIMFVANLTLGLYVQLVPRTLTPNSTVEIV---------------------------------------------------------------TLGGTEQPPAAAFNYLTLIPLLATMLFIMGYAMGWGPITWLLMSEVLPLRARGVASGLCVLVSWLTAFVLTKYFLLAV------VPFFFFSAICLLSLLFTGCCVPETRGRSLEQIEAFFHTRRMSFRP--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UDF0-1", "uniprot_id": "GTR6_MOUSE", "id": "Q3UDF0-1", "name": "Solute carrier family 2, facilitated glucose transporter member 6", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQEPLLRTEGLDYDTFPEVPATPGERERAGA----------------------------------------------------------------------------------------------------------------------------------------------LKNRRVFLATFAAVLGNFSFGYALVYTS------PVIPELKLS-SDPALHLDKIQASWFGSVFTLGAAAGGLSAMLLNDLLGRKLSIMFSAVPSAIGYAIMAGARG-LWMLLLGRMLTGFAGGLTAACIPVYVSEIAPPDVRGALGATPQLMAVFGSLSLYALGLLLP-------WRWLAVAGEGPVLIMILLLSFMPNSPRFLLSKSRDEEALQALTWLRADSEVHWEFE--------QIQDNVRRQSSRVSWAEAREPRVYRPVLIAVLMRFLQQLTGITPILVYLQTIFDNTSVV--LPSQQDAAIVGAVRLLSVLIAAVTMDLAGRKVLLYVSASVMFAANLTLGLYVQFVPRPLTPNSTVEIV---------------------------------------------------------------TLGDT------AFNYLTLIPLLATMLFIMGYAMGWGPITWLLMSEVLPLRARGVASGLCVLVSWLTAFVLTNYFLLAVNAFGLQVPFFFFSAICLLSLLFTGCCVPETRGRSLEQIEAFFHTRRMSFRP--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JJZ1-1", "uniprot_id": "SL2A8_RAT", "id": "Q9JJZ1-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPE--DPQETQPLLRSPGARAPGG--------------------------------------------------------------------------------------------------------------------------------------------------RRVFLATFAAALGPLSFGFALGYSS------PAIPSLRRT-APPALRLGDTAASWFGAVVTLGAAAGGVLGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARD-VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAGWVLE-------WRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWG-SEEGWE------------EPPVGAEHQGFQLAMLRRPGVHKPLIIGICLMVFQQLSGVNAIMFYANTIFEEAKFK--DSS-LASVTVGIIQVLFTAVAALIMDRAGRKLLLALSGVIMVFSMSAFGTYFKLTQSGPSNSSHVGLL---------------------------------------------------------------VPISAEP--ADVHLGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHIKGVATGVCVLTNWFMAFLVTKEFNSIMEILRPYGAFWLTAAFCILSVLFTLTFVPETKGRTLEQITAHFEGR--------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8MKK4-1", "uniprot_id": "TRE12_DROME", "id": "Q8MKK4-1", "name": "Trehalose transporter 1-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKILMRADTHVSFSVP-----ADGLKAN-----------------------------------------------------------------------------------------------------------------------------------------------FTFSQVLAALSVSLCSLVVGFVSAYTS------PALVSMTDR-TITSFEVTKDAGSWVGGIMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVN-VIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAGSFMN-------WSMLAFLGAALPVPFLILMIIIPETPRWFVNRGQEERARKALKWLRGKEADVEPELKEL----MQSQADADRQATQNTCLELFKRNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGST--IDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSILGGFFYCKA-----------------------------------------------------------------------------------HGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGRVP-MSSVVNIKPFPFNM---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8N1-1", "uniprot_id": "TRE11_DROME", "id": "A1Z8N1-1", "name": "Trehalose transporter 1", "aln": "MSGRDNRGAGGGGGGHQPLSNAMGKLKEKLTRVGDELGYHRVESNLSTSNTATSLDTILPEDPFLFPQVSPQRHPQNTVRTQRLLEDEPPLSFRPLLEDDDINEPPTQQQQRTPLRASGSLELTPLPPPPTSLEIREHRDRQQRGAQGDELQRSKQSLKGSRVSFERRDTGNSNTNSNKAAESSDEDSFEEKRTGFQQQKATSVDHKGILKDLKHILANDNRRQFQAKKHVSLDVKGTRFLQDLLKESSSEEEFHKTRREFQGRKHQSLDPRVTFKLDKVLQGSSTDSDEEGEDAEHKRLIHRPKDITKPVIIDLKDLESESDEDFLTSRQHFQQQRSISTDSRKSRRLYEMDEMDNKRGENIRHAVPFVRQITEDGKPKLEVYRPTTNPIYIWTQVLAALSVSLGSLVVGFVSAYTS------PALVSMTDR-NITSFEVTQDAGSWVGGIMPLAGLAGGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVN-VAMVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCFVAGSFMN-------WSMLAFLGAALPVPFLILMFLIPETPRWFVGRGLEERARKALKWLRGKEADVEPELKGL----MRSQADADRQASRNTMLELLKLNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGST--IDGNLCTIIVGIVNFLATFIGIVLIDRAGRKILLYVSDIAMVLTLFVLGGFFYCKT-----------------------------------------------------------------------------------YGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIYVPETQGKTLEDIERKMMGRVRRMSSVANIKPLSFNM---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VU17-1", "uniprot_id": "Q9VU17_DROME", "id": "Q9VU17-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTASSSNSSGEEANKKSGSNNEESSHLLESAENGAKYGSRQPVKIVKASDNGRTSSTPHDQENLLGNMVHTSTSNNS-----------------------------------------------------------------------------------------------------------------------------------------------QKWPQYVAALAAAGGAFAAGTVLGWTS------PAETEIVDRGEGYDFPVDKDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVN-VSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAGVK-------IFWLSIICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAEL----RETDRETKANKVN-VWAALNRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTG--IEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQ----------------------------------------------------------------------------------DAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNRSTPQAIPAEK---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JQU1-1", "uniprot_id": "A8JQU1_DROME", "id": "A8JQU1-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSEKVVRAMARWWQTVSQEDGD----------------SRNPITYDLLQENQSKTSKTRQYVAAMIICLGAVAAGTA-----------------------------------------------------------------------------------------------------------------------------------------------LSWTSPVFPQISAGNESSFNSTTGGIS------NSTSNEND------IRLTDSQKTLVGSMLPFGALFGALPSGYIADRIGRRYTAMVMDIPFILAWITLSFANS-VGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGILFIYVVGALVS-------WKTLSLLCLIIPILLLVGLFIVPETPVYLLKNGKRSEANRALKWLWG-DYCNTSNAIQA----IQNDLDQTGVDAS-VKDLFSNRASRNGMVISVLLMVFQQFSGINAVIFFMNEIFESSST---LNPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLIFSSTIMTVCLAMLGAYNTINR-----------------------------------------------------------------------------------HTDLSQSIGWLPLLCIVLFIVSFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSLVTWLFGVLNAG-GADVPFWFFSAWMGVATAYVAIALQETKGKSASQIQSWLSGR--------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54862-1", "uniprot_id": "HXT11_YEAST", "id": "P54862-1", "name": "Hexose transporter HXT11", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGVNNTSANELSTTMSNSNS-----------------AVGAPSVKTEHGDSKNSLNLDANEPPIDLPQKPLSAYT--------------------------------------------------------------------------------------------------------------------------------------------------TVAILCLMIAFGGFIFGWDTGTISGFVNLSDFIRRFGQKNDKGTYYLSKVRMGLIVSIFNIGCAIGGIVLSKVGDIYGRRIGLITVTAIYVVGILIQITSINKWYQYFIGRIISGLGVGGIAVLSPMLISEVAPKHIRGTLVQLYQLMGTMGIFLGYCTNYGTKNYHNATQWRVGLGLCFAWATFMVSGMMFVPESPRYLIEVGKDEEAKRSLSKSNKVSVDDPALLVEYDTIKAGIELEKLAGNASWSELLSTKTKVFQRVLMGVMIQSLQQLTGDNYFFYYGTTIFKSVGLK---DSFQTSIIIGVVNFFSSFIAVYTIERFGRRTCLLWGAASMLCCFAVFASVGVTKLWPQGSS----------------------------------------------------------------------------HQDITSQGAGNCMIVFTMFFIFSFATTWAGGCYVIVSETFPLRVKSRGMAIATAANWMWGFLISFFTPFITGAINFYYGYVFLG-CLVFAYFYVFFFVPETKGLTLEEVNTMWLEGVPAWKSASWVPPERRTADYDADAIDHDNRPIYKRFFSS------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : . . . :. : : : **: : . : . .* *. . . : .* ** * * : : . : :* * : . : : : : * * .: : :: . : :* :... . :: * : * . * :. : .:: :: . ::::.* :. . .. .* .:: : . : : **:* : :: ", "identical_positions": 23, "similar_positions": 80, "identity": "2.31%" }, { "cls_id": "homologset.agr.SGD:S000005517", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91WV7-1", "uniprot_id": "SLC31_MOUSE", "id": "Q91WV7-1", "name": "Amino acid transporter heavy chain SLC3A1", "aln": "MDEDKGKRDPIQMSLKGCRTNNGFVQNEDIPEQDPDPG-SRDTPQPNAVSIPAPEEPHLKAVRPYAGMPKEVLFQFSGQARYRVPREILFWLTVVSVFLLIGATIAIIVIS-------PKCLDWWQAGPIYQIYPRSFKDSDKDGNGDLKGIQEKLDYITALNIKTLWITSFYKSSLKDFRYAVEDFKEIDPIFGTMKDFENLVAAIHDKGLKLIIDFIPNHTSDKHPWFQSSRTRSGK-YTDYYIWHNCTHVN--GVTTPPNNWLSVYGNSSWHFDEVRKQCYFHQFLKEQPDLNFRNPAVQEEIKE-IITFWLSKGVDGFSFDAVKFLLEAKD-----LRNEIQVNTSQIPDTVTHYSELYHDFTTTQVGMHDIVRDFRQTMNQYSREP--GRYRFMGAEASAESIERTMMYYGLPFIQEADFPFNKYFTTIGTLSG----------HTVYEVITSWMENMP-EGKWPNWMTGGPETPRLTSRVGSEY-------VNAMHMLLFTLPGTPITYYGEEIGMGDIS-----------------VTNFNESYDSTTLVS-------------KSPMQWD-NSSNAGFT-EANHTWLPTNSDYHT-VNVDVQKTQPSSALRLYQDLSLLHAT---ELVLSRGWFCLLRDDSHSVVYTRELDGIDNVFLVVLNFGESSTVLNLQGIISDLPPELRIRLSTNSASK--GS-AVDTRAISLEKGEGLVLEHSTKAPLHQQAAFRDRCFVSSRACYSSALDILYSSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64319-1", "uniprot_id": "SLC31_RAT", "id": "Q64319-1", "name": "Amino acid transporter heavy chain SLC3A1", "aln": "MNEDKDKRDSIQMSMKGCRTNNGFVQNEDIQEQDPD---SRDTPQSNAVSIPAPEEPQLKVVRPYAGMPKEVLFQFSGQARYRVPREILFWLTVVSVFLLIGATIAIIIIS-------PKCLDWWQAGPMYQIYPRSFKDSDKDGNGDLKGIQEKLDYITALNIKTIWITSFYKSPLKDFRYAVEDFKEIDPIFGTMKDFENLVAAVHDKGLKLIIDFIPNHTSDKHPWFQSSRTRSGK-YTDYYIWHNCTHAN--GVTTPPNNWLSVYGNSSWQFDEERKQCYFHQFLKEQPDLNFRNPAVQEEIKE-IIKFWLSKGVDGFSFDAVKFLLEAKD-----LRNEIQVNTSQIPDTVTRYSELYHDFTTTQVGMHDLVRDFRQTMNQFSREP--GRYRFMGTEVSAESTERTMVYYGLSFIQEADFPFNKYLATLDTLSG----------HTVYEAITSWMENMP-EGKWPNWMIGGPETSRLTSRVGSEY-------VNAMNMLLFTLPGTPITYYGEEIGMGDIS-----------------ITNLNERYDTNALLS-------------KSPMQWD-NSSNAGFT-EANHTWLPTNSDYHT-VNVDVQKTQPSSALRLYQDLSLLHAR---ELLLSRGWFCLLRDDNHSVVYTRELDGIDKVFLVVLNFGESSTVLNLQETISDVPTKLRIRLSTNPASK--GS-DVDTHAVSLEKGEGLILEHSMKTLLHHQKAFRDKCFISNRACYSSVLDLLYSSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07837-1", "uniprot_id": "SLC31_HUMAN", "id": "Q07837-1", "name": "Amino acid transporter heavy chain SLC3A1", "aln": "MAEDKSKRDSIEMSMKGCQTNNGFVHNEDILEQTPDPGSSTDNLKHSTRGILGSQEPDFKGVQPYAGMPKEVLFQFSGQARYRIPREILFWLTVASVLVLIAATIAIIALS-------PKCLDWWQEGPMYQIYPRSFKDSNKDGNGDLKGIQDKLDYITALNIKTVWITSFYKSSLKDFRYGVEDFREVDPIFGTMEDFENLVAAIHDKGLKLIIDFIPNHTSDKHIWFQLSRTRTGK-YTDYYIWHDCTHEN--GKTIPPNNWLSVYGNSSWHFDEVRNQCYFHQFMKEQPDLNFRNPDVQEEIKE-ILRFWLTKGVDGFSLDAVKFLLEAKH-----LRDEIQVNKTQIPDTVTQYSELYHDFTTTQVGMHDIVRSFRQTMDQYSTEP--GRYRFMGTEAYAESIDRTVMYYGLPFIQEADFPFNNYLSMLDTVSG----------NSVYEVITSWMENMP-EGKWPNWMIGGPDSSRLTSRLGNQY-------VNVMNMLLFTLPGTPITYYGEEIGMGNIV-----------------AANLNESYDINTLRS-------------KSPMQWD-NSSNAGFS-EASNTWLPTNSDYHT-VNVDVQKTQPRSALKLYQDLSLLHAN---ELLLNRGWFCHLRNDSHYVVYTRELDGIDRIFIVVLNFGES-TLLNLHNMISGLPAKMRIRLSTNSADK--GS-KVDTSGIFLDKGEGLIFEHNTKNLLHRQTAFRDRCFVSNRACYSSVLNILYTSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z7F2-1", "uniprot_id": "A1Z7F2_DROME", "id": "A1Z7F2-1", "name": "alpha-glucosidase", "aln": "---------------------------------------------------------------------------------MQGTRLDHFGLLVCGLVILAHPSWSCET-----TTSTTVTKDWWENAQFYQIYPRSFMDSDGDGIGDLNGITSKLEYLKDLGVTAAWLSPIFTSPMVDFGYDISDFFDIQPEYGTLDDFRALIKRANELDLKIILDFVPNHSSDENSWFVKSVNREKG-YEDYYVWHDGRVNATTGGREPPSNWLQAFRGSAWEWNEKRQQYYLHQFAVQQADLNYRNPLVVEQMKR-VLRYWLDLGVAGFRCDAVPVLFEIEPDADGQYADEELSGLTD---DVDDRKYLKSDLIENRPETIDMAYQWRVVMDDYQRIH-GGETRVLLIETYAPPAYTMQFYGNRS-TAGAHLPFNFNLITVLASD-------GVSAGSIKTAVDNWLDNLP-AGRTANWVIGNHDQRRAASRYGTAN-------ADAMNMLVMVLPGASVTYQGEELGMTDG------------------EISWEDTQDPAACNSNSDIYEQFTRDPSRTPFQWT-NGTNAGFS-TASKTWLPLAADYQT-LNVETEAAAQRSHLKIYKALVELRKSS---LPLQNGSTKYGVVGENVFVVKRYISGSA-SIIYVANFASKGVTVDLYEFDKTLPTHLTLLIRSLQSSKAEGS-QFEVTGLSLAAGEALVLSSSSSSRFD----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z7F3-1", "uniprot_id": "A1Z7F3_DROME", "id": "A1Z7F3-1", "name": "alpha-glucosidase", "aln": "--------------------------------------------------------------------------------------MELLSLLTLLLLAIASNEACQVQ-----SSSSETTKDWWQTAQFYQIYPRSFKDSDGDGIGDLNGITSKLEYLKDLGVTAAWLSPIFKSPMVDFGYDISDFFDIQPEYGTLEDFRTLIKRAKELDLKIVLDFVPNHSSNESEWFLKSVKREKG-YEDYYVWHDGKVNSTTGKREPPTNWLQYFRGSAWEWNEVRQQYYLHQFAVQQPDLNYRNPLVVEQMKR-VLRYWLNEGVSGFRCDALPPLFEVVPDSDGQFPDEVVSGATE---DKEDRDYLTTTYIENQPETIDMVYQWRTVLDDHKRIF-GGNSSVLLIETYSPAWFTMQFYGNRS-TEGAHLPFNFNLITVMEQS-------GLSASNVQEAIDLWLKNMP-AGRTPNWVLGNHDKRRAASRYGKEN-------IDGMNMLVMILPGVSVTYQGEEIGMTDG------------------EISWEDTVDPWGCNSNPNIYEQYTRDPERTPFQWT-GGTNAGFT-NGSSTWLPLAADYAT-INVEKELSDDHSHLKIYKALVALRKSS---KTLQNGSTKYQALSEDIFVVQRSLTKSA-TIVLVINFGSVAKTVDLSQFDKSRTESLQLLIRSIDSTKKEGT-RYDPKALSLDPSEALVLTTE----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z7F1-1", "uniprot_id": "A1Z7F1_DROME", "id": "A1Z7F1-1", "name": "alpha-glucosidase", "aln": "---------------------------------------------------------------------------------MACFKVLIAAILVLGIHCALGSAAAVDLDLERATTAADTTRDWWQVAQFYQIYPRSYKDSDGDGIGDLQGIISKLDYLKEIGVTATWLSPIYSSPMADFGYDISDFFDIQPEYGTLADFDELIAEAKKRNIKIILDFVPNHSSDENVWFQKSVKREKG-YEDYYMWHDGYVNATTGKREPPSNWLQAFRGSAWEWNDERQQYYLHQFAVKQPDLNYRNPAVVAQMKR-VLTYWLDRGVAGFRMDAVPWCFEVLPDADGRYPDEPLSGYTD---DPDDSSYLKHIYTQDLRETVEMVFQWRTLLDDYQRIH-GGDTRVIMVETYSGLDYVMQFYGNRT-TKGAQMPFNFQFIIGGNGDKNNT---QLNATGFVKIISSWLSQMP-AGQTANWVMGNHDQRRVGSRYGENR-------IDLMNMLQMFLPGVSITYQGEELGMTDL------------------DISWEDSRDPAACNSNSDIYEQFTRDPARTPFQWS-DEANAGFS-TNATTWLPINPNYVT-VNAKAENSTSPSHLSLYKQLVDLRKS----KTLQFGATRYANVGDNVVAIRRYLSGEP-SYVLVANVLDTSVSGIDVASAIYATGSYKIKLLNPQAKATVGD-SVTLSNLTLEPYAALILESV----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07190-1", "uniprot_id": "MAL1_DROME", "id": "P07190-1", "name": "Maltase A1", "aln": "------------------------------------------------------------------------------------MRPQSAACLLLAIVGFVG------------------ATEWWESGNYYQIYPRSFRDSDGDGIGDLNGVTEKLQYLKDIGFTGTWLSPIFKSPMVDFGYDISDFYQIHPEYGTMEDFERMIAKAKEVGIKIILDFVPNHSSTENEWFTKSVDSDPV-YKDFYIWHDGKINNETGEREPPSNWNSEFRYSAWEWNEVRQQYYLHQFAIQQADLNYRNPAVVNEMKN-VIRFWLGKGVSGFRIDAVPYLFEVDLDRYNQYPDEPLTNDSVNCPDPDDHCYTQHIYTQDMPETIDMVYQWRELVDEFHVEN-GGDKRLLMTEAYTSFENIMTYYGNGV-RNGSHIPFNFDFLTSINNAS--------KAGEYVEHIKKWMDAMP-EGVYANWVLGNHDNKRVASRFGVQR-------TDLINILLQTLPGHAVTYNGEELGMTDV------------------WISWEDTVDPNACNSDPDNYYARSRDPARSPYQWD-ASSKAGFT-SADHTWLPVADDYKT-NNALQQLRAPRSHLQIFKKLVRVRKE----PSFRQGELNIQAIDDDVIIYSRQKTGSD-LYVIVLNLGSTSKTLDLTKYYELG-TQAEVITTSLSSQYIDGD-VIKSTEFVANPYVGTVLVAV----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07192-1", "uniprot_id": "MAL3_DROME", "id": "P07192-1", "name": "Maltase A3", "aln": "----------------------------------------------------------------------------------MFKLLVLSCLLALALPSLAEVG-------------------WWKTGQFYQIYPRSFKDSDGDGVGDLIGITQQLPYLKEIGITATWLSPIFTSPMADFGYDVADLKGIDPIFGTMEDFEALLARAKELDIKIILDFVPNHTSDECDWFIRSAAGEEE-YKDFYVWHTGKVVN--GIRQPPTNWVSVFRGSMWTWNEQRQAYYLHQFHAKQPDLNYRNPKVVEAMKD-VLRFWLRKGAYGFRIDAVPHVYEIPADADGNWPDEPRNEAVS---DPEDYTYLQHIYTTDQPETLELVYAFRDVIEEIDAEL-GGDDRVLLTEAYSPLEVLMQYYGNGT-HLGSQIPFNFELLAKISYSS--------DAYHYSELIHNWLDNMP-EGQVANWVFGNHDQSRIGSRLGADR-------IDACNMIILGLPGVSVTYQGEEMGMTDV------------------WISWEDTVDPQACQSNEQEFERLTRDPVRTPFQWS-DEVNAGFS-NASVTWLPVASNYKL-VNVKKERGIALSHLNVYKQLRALRDE----PTLKQGDVSVTAIGPNVLAFKRSLAGYK-SYITLININDDVESINLDSVFTSITTQLQYVVVNDKSVRRKND-LTFANSVLLLPKEAVVLSTV----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z7E8-1", "uniprot_id": "A1Z7E8_DROME", "id": "A1Z7E8-1", "name": "alpha-glucosidase", "aln": "----------------------------------------------------------------------------------MTTWTSLFLLLGLGLLAVDAAAP------------------WWKTASFYQIYPRSFKDSDGNGVGDLNGVTEKLEYLKEIGVTATWLSPFLKSPMADFGYDISDFKAVDPLFGTMEDFENMVSRAKELGVKIILDFVPNHSSDECDWFLRSAAGEEE-YKDYYMWHPGFLDED-GTRRPPTNWVSVFRGSAWEWHEGRQEYYLHQFHKKQPDFNFRNPVVREEMNN-VLRFWLEKGVDGFRVDAIYHAFEIEADENGNYPDEPRNDWTN---DPDEYGYTHKIYTVDQPETPHLVYEWRQILEQFQADN-GGDERILMVETWSPIEIVMHYYGNET-ADGAQIPFNFQLISNLHYDS--------DAYHYEYLINNWLNLMP-EGKSANWVIGNHDKNRVGSRFGADR-------VDLFNILLLTLPGCSITYQGEELGMLDG------------------YVSWEDTVDPQACNGYEANYMDNSRDPARTPMHWS-DETMAGFT-TGNSTWLPVSTDYRQ-RNVKTERGVSLSHLNVFKRLQQLRQE----PSIEEGSAEVKAVSNYVLAVKRHLSGDF-VYISLFNIFDSIENVNLSSVFGSLPAKFQYALVTEKSIKKVGD-QVSAGSVTLMPHESIVLRSTTTA-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07191-1", "uniprot_id": "MAL2_DROME", "id": "P07191-1", "name": "Maltase A2", "aln": "----------------------------------------------------------------------------------MPKWAHLGLAALLLISTTQEGTAD---------------IDWWENASLYQIYPRSFQDSDGDGIGDLKGITSRLGYLKEIGITATWLSPIFTSPMSDFGYDISNFYDIDPIFGTLEDFDDLIVEAKSLGVKIILDFVPNHSSDENVWFEKSVNREDG-YDDFYVWDDGKLNEETGARDPPSNWVSVFSGPMWTWNEKRQQYFLHQFQVKQPDLNFTNPMVREHMLD-VLKFWLDRGVDGFRIDAVPHIYEHRN-ADGSYPDEPVSGWGS---DPNAYDYHDHIYTKDQPATVDLMYEWREFLDNYRAQN-GGDSRVLLAEAYSSVETLSAYFGNST-HQGTQLPMNFQLMYLSGYS---------TAKDVVGSIDYWMNTMWKEHQTANWVVGNHDTNRVADRMGAHK-------VDLLNVIVNALPGASVTYYGEEIGMSNV------------------DVECTG----DSCE---------DRDGERTPMQWT-AGKNADFS-DGESTWLPLSPEYQR-YNVQTERGVSRSSLNIFKGLQELKSSSAFLAFKEDGGFSYEAVTEQVLQIIRTNKISE-EYRILVNMGNGMEILD-----GLAPKTYEYVLATAYSTHYSGQKADLSQRIILMPYEAVVLRWLA---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKE6-1", "uniprot_id": "Q9VKE6_DROME", "id": "Q9VKE6-1", "name": "alpha-glucosidase", "aln": "-----------------------------------------------------------------------------------MVVVKIAFILSVGLVGILAHKHQSK--------ELDAKYNWWQHEVFYQIYPRSFQDSNGDGIGDLQGITSRLQYFKDTGITSVWLSPIYESPMVDFGYDISNYTNIQPEYGTLEDFDALIAKANELGVKVILDFVPNHSSNKHPWFIKSVAREPG-YEDFYVWEDG-ILLENGTRVPPNNWLSVFSGSAWMWNDERQQYYLRQFTYGQPDLNYRNPAVIKAMDD-VMLFWLNKGIAGFRIDAIIYIYEDAQ-----LRDEPPSGTTD---DPNNEAYLSHIYTRNQPEDYGLLQHWRQLLDNYTANH-DGPLRIMMTEGYASVSQLMEYYEDSNGVQGPQFPFNFDFITELNANS--------TAADFVFYISRWLIYMP-HGHVANWVMGNHDNPRVASRFGEKS-------VDAMNMLLMTLPGIGITYNGEELGMTDYR-----------------DISWSDTVDQPACEAGIDNYKTISRDPERTPMQWS-SDVNAGFS-SADRTWLPVNPNYKE-LNLRNQQQARRSHYKIYQSLLKLRQL----PVLKNGSFVPEVVNRRVFAFKRELKNEH-TLLTIVNVSNRTELVDIADFIEQP-NRLSVLVAGVDSQHRVGD-RLKAETIELAPNEGLVIQLNKRK-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A4P1SA55-1", "uniprot_id": "A0A4P1SA55_DROME", "id": "A0A4P1SA55-1", "name": "alpha-glucosidase", "aln": "---------------------------------------------------------------------------------MRAPLIQILLFSLLNSGSIMAGLVKS---------DTEDFIDWWPHTVFYQIYPRSFKDSNGDGIGDLKGITSKLRYLADTGITATWLSPIFQSPMIDFGYDISDYKAIQPEYGTMQDFEELIDTAFELGIKVVLDFVPNHSSDQHEWFKKSAAREPG-YEDFYVWHDG-IVQENGTRVPPNNWPSVFYGSAWEWHEGREQYYLHQFTKEQPDLNYRNPKVVQAMDD-VLLFWLNKGVAGFRIDAVNHLFEDES-----LKDEPLSGKTT---DSLSYDYTKHIYSRDLPEVLEMIHHWRQLLDDFSAKHPERPTRIMMTEAYAGLTQLADYYEDSNGVRGSHLPFNFHFITDVKGDS--------DARDYVYNVEKWLIYMP-RGHAANWVMGNHDNPRVASRFGPAS-------VDAMNMLLLTLPGVAVTYNGEELGMVDYR-----------------ELSWEETVDPPARNVGEKLYQEVSRDPVRTPFQWN-NETNAGFS-TAAKTWLPVHPNYLE-LNLEAQKVANRSHYQVYKDLLELRKS----AIMRVGRFNIEPLTRWVFAFKRSYPNFE-SIITVINVSDKEQLVDLSEFLSQP-KKLVVEVSGVDSKYQPGQ-SLAASALLLAAREGLVCRLV----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08295-1", "uniprot_id": "IMA2_YEAST", "id": "Q08295-1", "name": "Oligo-1,6-glucosidase IMA2", "aln": "-------------------------------------------------------------------------------------------MTISSAHPETEP-------------------KWWKEATIYQIYPASFKDSNNDGWGDMKGIASKLEYIKELGADAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWRSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVAG-----LPDAPVIDENS-------KWQPSDPFTMNGPR----IHEFHQEMNKFIRNRVKDGREIMTVGEMQHATDETKRLYTSASRHELSELFNFSHTDVGTSPKFRQNLIPYELKDWKVALAELFRYVNGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLVSLSGTLYVYQGQELGEINFKNWPIEKYEDVEVRNNYDAIKEEHGENSKEMKRFLEAIALISRDHARTPMQWSREEPNAGFSGPNAKPWFYLNESFREGINAEDESKDPNSVLNFWKEALRFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYDNKT--LFAALNFSSDSIDFTIPNNSSSFKLEFGNYPRS----------EVDASSRTLKPWEGRIYISE----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ***** *: **: :* **: *: .:* *: . *::.: *. *: * : : : * :** * :: . .:*.: *:: ** * : ** * *::.* * **.** . : . * :.: : ::: * *.*:*: * : : :** * ** *. : : :: ::. .: :* : : : .. . : * * * . :: *.* .* *:*:* : . ::* :* *.*: .*: .: * : * .:: .: . . : *. . . : ", "identical_positions": 69, "similar_positions": 98, "identity": "9.07%" }, { "cls_id": "homologset.agr.SGD:S000005527", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A1X2-1", "uniprot_id": "EXOSX_RAT", "id": "D4A1X2-1", "name": "Exosome complex component 10", "aln": "MAPPSPREHQSAPATGATKPDAEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQVGDEYDFYRSFP-AFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDTNDVILERVGILLDEASGVNKHQQPVLPAGLQVP-----------------KTIVSSWNRKAGEYGKKAKAETFRLLHAKNILRPQLRFREKIDN-SNTPFLPKIFVKPNARKPLPQALSKERRERPQDRPEDLDVPPALADFIHQQRAQQVEQDVFAHPYQYELDHFTPPPSVLQRPQPQLYRPVEETPCHVVSSLDELVELNEKLLGCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIVDTLELRSDMYILNESLTDPAIVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLARHSLDHLLRLYCGVESNKQYQLADWRIRPLPEEMLNYARDDTHYLLYIYDRMRLELWERGNDQPVQLQVVWQRSRDICLKKFVKPIFTDESYLELYRKQ-------KKHLNSQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSETAAGVKKSGPLP-SAERLENDLFGPHDCSHAPPDNYPVTSTDGTMPLQKQPSLFDEGKEETSVDARCLLATAVITLFSEPSTEEA---------------------GKTPLTVAQKKAQSIMESFENPFRMFLPSLENKAHISQAAKFDPSSKIYEISNRWKLAS--QVQKEPKEAAKKKVAEQTAAREETKEESTAAVLEQPIPVRQQAALENATKKRERATSDLRTIEQKQE--KKRLKSSKKAKDPDPPGKDFSPYDYSQSDFGAFAGDSKSKPSSQFDPN----KVAPSGKKCFGAKKFKQSVGNKSMSFPAGKSDRGFRHNWPKR------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56960-1", "uniprot_id": "EXOSX_MOUSE", "id": "P56960-1", "name": "Exosome complex component 10", "aln": "MAPPSPREHQSAPATSATKPDAEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEYDFYRSFP-AFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDTNDVILERVGMLLDEASGVNKHQQPVLPAGLQVP-----------------KTIVSSWNRKAGEYGKKAKSETFRLLHAKNIVRPQLRFREKIDN-SNTPFLPKIFVKPNARKPLPLALSKERRERPQDRPEDLDVPPALADFIHQQRTQQVEQDMFAHPYQYELDHFTPPQSVLQRPKPQLYRAVGETPCHLVSSLDELVELNEKLLGCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIVDTLELRSDMYILNESLTDPAIVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLARHSLDHLLRLYCGVESNKQYQLADWRIRPLPEEMLSYARDDTHYLLYIYDRMRLELWERGNHQPVQLQVVWQRSRDICLKKFVKPIFTDESYLELYRKQ-------KKHLNSQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSENAAGVRKSGPLP-SAERLENDLFGPHDCSHAPPDNYQNTSTDGTLPLQKQPSLFTEGKEETSVDAGCLLATAVITLFSEPNTEEG---------------------GKTPLTVAQKKAQNIMQSFENPFRMFLPSLEHKAHISQAAKFDPSSKIYEISNRWKLASQVQVQKEPKEATKKKVAEQTAAREEAKEEAAAGVLEQAIPVRQQAALENATKKRERATSDLRTIEQKQE--KKRLKSSKKAKDPDPPGKDFSPYDYSQSDFRAFAGDSKSKPSSQFDPN----KLAPSGKKGVGAKKCKQSVGNKSMSFAVGKSDRGFRHNWPKR------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01780-1", "uniprot_id": "EXOSX_HUMAN", "id": "Q01780-1", "name": "Exosome complex component 10", "aln": "MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEYDFYRSFP-GFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVILERVGILLDEASGVNKNQQPVLPAGLQVP-----------------KTVVSSWNRKAAEYGKKAKSETFRLLHAKNIIRPQLKFREKIDN-SNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADFIHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVELNEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPAIVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQLADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKKFIKPIFTDESYLELYRKQ-------KKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLP-SAERLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITLFNEPSAEDS---------------------KKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEISNRWKLAQ-VQVQKDSKEAVKKKAAEQTAAREQAK-EACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQE--KKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPN----KQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFF3-1", "uniprot_id": "EXOSX_DROME", "id": "Q9VFF3-1", "name": "Exosome complex component 10 homolog", "aln": "-MPRTPKRVHQEAKEESAQADQPPKKSASEDVEAFTNKGFKNAIAATKAANAFPQG-TARALYLSYP-GYARVMEDLTQRVVALIGNVLHSKDIKGDIKKR----QPEEQFEMVQECNDVLFERITTNLDIKGGLRRNTQQVVEAQVDVMSSSTSIEPAVASPQTQGTPKAGSWNRTTGTP--QRSMVSARLFTAKNIVRPQTQFREPVDNSAQNPFVPRLKEKPNSLKPLALLPEYDDAGNVQS---------------------------YLHPYEFELLKFQPPEEQFQKQKPVLPALMAETELMVVDTVEKLKQALEELRQAPQIAIDVEHHSYRTFMGITCLVQMSTRSKDYIFDTLILRDDMHILNLVLTDPKKLKILHGADLDIEWLQRDLSLYIVNMFDTHRAAKALNMARLSLAYLLKHYLDLDVDKSLQLADWRMRPLPQQLVDYARQDTHFLIYVYGRMTNDLLQQ-HAEPGLLGSVYQQSTDVCKKRYNKPHIGPESHLDLVRKT-------KRSFDNRQLYALRGIFEWRDATARSEDESYGYVLPNHMMLQIAESLPREMQGILACCNPIPPLVRQQLHTLHQIVLKARDQPLVKPILEAHSSTQAALPPSTKDFSSKLYCPHDFSQLEEIRDDLPTLLKRNSTTGKLEVPNKEEVAKVDPTLAAPAMALFEKQSKPTQEEEQRWAHLRKESQTMRMPYKRYLAILPLMVQLKADQLARERSELQKRQLCP---AAPTVEQNIKLEAHAIGKEDDDMYSVPLKEQLKRKHPQANVKTDPEQQPTASKRPRKDENSQTKPPVKIEPVEKVQQALGESDDEVVEVPIERQATEPPKPSPAQNNRKQKKNQFQRGFKAKNRGNHPQSSSQQVPQHKGTGNFDYKNVDFRQFKGGAQRARGTEIKQQIRGKNRPNNRNNKQFNKLFTFSNVRKEGKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12149-1", "uniprot_id": "RRP6_YEAST", "id": "Q12149-1", "name": "Exosome complex exonuclease RRP6", "aln": "--------------------------MTSENPDVLLSRVINVVRAASSLAS------QDVDFYKNLDRGFSKDLKSKADKLADMANEIILSIDEH------------HESFELKEEDISDLWNNFGNIMDNLLEMSDHSLDKLNCAINSK-------------------------SRGSDLQYLGEFSGKNFSPTKRVEKPQLKFKSPIDNSESHPFIPLLKEKPNALKPLSESLRLVDDDENNP-------------------------SHYPHPYEYEIDHQEYSPEILQIREEIPSKSWDDSVPIWVDTSTELESMLEDLKNTKEIAVDLEHHDYRSYYGIVCLMQISTRERDYLVDTLKLRENLHILNEVFTNPSIVKVFHGAFMDIIWLQRDLGLYVVGLFDTYHASKAIGLPRHSLAYLLENFANFKTSKKYQLADWRIRPLSKPMTAYARADTHFLLNIYDQLRNKLIESNKLAGVLYESRNVAKRRFEYSKYRPLTPSSEVYSPIEKESPWKILMYQYNIPPEREVLVRELYQWRDLIARRDDESPRFVMPNQLLAALVAYTPTDVIGVVSLTNGVTEHVRQNAKLLANLIRDALRN------IKNTNEEATPIPSSETKADGILLETISVPQIRDVMERFSVLCNSNISKSRAKPVTNSS------------------------------------------------ILLGKILPREEHDIAYSKDGLPNKVKTEDIRIRAQNFKSALANLEDIIFEIEKPLVVPVKLEEIKTVDPASAPN-----HSPEIDNLDDLVVLKKKNIQKKQPAKEKGVTEKDAVDYSKIPNILSNKP-----------------------------------GQNNRQQKKRRFDPS------SSDSNGPRAAKKRRPAAKGKNLSFKR--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . : . *.:. :. :* . .: : ::: ..:: . : .:.*:: : . : :.. :* : : : . :: . . .: :*.: :** :*:. :** . **:* : ***: ***. . : : ***::*: : . :* : :: :.: :* . *.* ::*:*:***.**:: *:.**:*:*** .*::.*** **.:::*** :*:* :*::*** ** ***:*:.**:*.:***::*:: :.: * ** :**. : ... .*. ******:***.: : *** ***:*: :*.:: .: : : . . .:: * : : :: : : .: .: :: *** ** :*** :*:**::: :. * : *::: * :. ***: : : :: .* .:* * .. * . . .: : . . . : : : . : . : : * .. :. : : * . : . . : : . : . : . . : : . .** . .. ..: : .*. . ", "identical_positions": 119, "similar_positions": 226, "identity": "12.57%" }, { "cls_id": "homologset.agr.SGD:S000005528", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3T1L5-1", "uniprot_id": "ALG6_RAT", "id": "Q3T1L5-1", "name": "Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "-------------MESWTWMTV-------------------VVLLGLTVRWTVSLNSYSGAGKPPMFGDYEAQRHWQEITLNLPVKQWYFNSSDNNLQYWGLDYPPLTAYHSLLCAYVAKFINPDWVALHTSRGYES--QAHKLFMRTTVLAADLLIYIPAVLLYCYSLKEIS---PKRKIASALCILLYPGLILIDYGHFQYNSVSLGFALWGVLGVSCDWDLLGSLAFCLALNYKQMELYHSLPFFCFLLGKCFKKGLRGKGSALFIRIACTVVASFLLCWLP--FLTE-REHALQVVRRLFPVDRGLFEDKVANIWCSLNVFLKIKDILPRHIQIAISFCFTFLSLLPACIKLTVQPSAKGFRFTLVSCALSFFLFSFQVHEKSILLVSLPVCLVLT----EIPFMSTWFLLVSTFSMLPLLLKDQLLLPSVVTVMAFLIACSTFFPMFENTSEEQLQLKSFAVSVRRHLPGFTFLPR--IIQCLFLSSVITMILLTILSVTLDPPQKLPDLFSVLICFVSCVNFVFFLVYFNIVIMWDSKNGRNRKKID", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TAE8-1", "uniprot_id": "ALG6_MOUSE", "id": "Q3TAE8-1", "name": "Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "-------------MESWPWMAV-------------------VVLLGLTVRWTVSLSSYSGAGKPPMFGDYEAQRHWQEITLNLPVKQWYFNSSDNNLLYWGLDYPPLTAYHSLLCAYVAKFINPDWVALHTSRGYES--QAHKLFMRATVLAADLLIYVPAVLLYCYSLKEIS---PKRKIASALCILLYPGLILIDYGHFQYNSVSLGFALWGVLGVSWDWDLLGSLAFCLALNYKQMELYHSLPFFCFLLGKCFKKGLKGKGLALFIRIACTVLASFLLCWLP--FLTE-REHALQVVRRLFPVDRGLFEDKVANIWCSVNVFLKIKDTLPRHIQIAISFCFTLLSLLPACIKLTVRPSCKGFRFTLVSCALSFFLFSFQVHEKSILLVSLPVCLVLT----EIPFMSTWFLLVSTFSMLPLLLKDELLLPSVVTVMAFVIACGTFFPMLENTSEEQLQLKSFAVSVRRHLPGFTFLPR--IMQCLFLSSVITMVLLTILSVTLDPPQKLPDLFPVLICFVSCVNFVFFLVYFNIVIMWDSKNGRNRKKIE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y672-1", "uniprot_id": "ALG6_HUMAN", "id": "Q9Y672-1", "name": "Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "-------------MEKWYLMTV-------------------VVLIGLTVRWTVSLNSYSGAGKPPMFGDYEAQRHWQEITFNLPVKQWYFNSSDNNLQYWGLDYPPLTAYHSLLCAYVAKFINPDWIALHTSRGYES--QAHKLFMRTTVLIADLLIYIPAVVLYCCCLKEIS---TKKKIANALCILLYPGLILIDYGHFQYNSVSLGFALWGVLGISCDCDLLGSLAFCLAINYKQMELYHALPFFCFLLGKCFKKGLKGKGFVLLVKLACIVVASFVLCWLP--FFTE-REQTLQVLRRLFPVDRGLFEDKVANIWCSFNVFLKIKDILPRHIQLIMSFCSTFLSLLPACIKLILQPSSKGFKFTLVSCALSFFLFSFQVHEKSILLVSLPVCLVLS----EIPFMSTWFLLVSTFSMLPLLLKDELLMPSVVTTMAFFIACVTSFSIFEKTSEEELQLKSFSISVRKYLPCFTFLSR--IIQYLFLISVITMVLLTLMTVTLDPPQKLPDLFSVLVCFVSCLNFLFFLVYFNIIIMWDSKSGRNQKKIS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JR12-1", "uniprot_id": "A0AC58JR12_DANRE", "id": "A0AC58JR12-1", "name": "Alpha-1,3-glucosyltransferase", "aln": "-MNSDDTSVSGGCCENYLLLPVKKQDE-----------DAILCRINIIRRSLYPFIYERCAGKPPMFGDYEAQRHWQELTYNLPVHEWYFNTTNNDLNYWGLDYPPLTAYHSLACAYIAKLFNPEWVELHASRGYES--HSHKLFMRATVLFADALIYIPAVLLYCFYFCDGS---PKQKVATAFCILMYPGLMLIDYGHFQYNGVSLGLALWGVLGLGLGWDLFGSVAFVLALNYKQMELYHALPFFCYLLGKCVKHGLNGQGFFHLVKISLTVLVTFALCWMP--FLSD-PKQPLQVLHRLFPVGRGLFEDKVANTWCSLNVLIKIKTLLSRETQLFLSFALTVLFVLPSSLKLLSKPTLWQFKLALVNSSLAFFLFSFQVHEKSILLAALPVCLVIN----EMPLIAVWFLLTSTFSMLPLLLKDGLLLPYVVTSLAFLFLSLYLLSALERSTDEELRLAPYRKLTQHFLPKLN-LSR--IVKWKFWLSLVAMAALSITSVWLEPPAKLPDLFPVLVSIFSFLHFLGFVIYFNLVQLMEPQRRKNQKKTN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKX7-1", "uniprot_id": "ALG6_DROME", "id": "Q9VKX7-1", "name": "Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "-------------MRSEILASA---------------------FLGLAVRSIISLYSYSGFDSPPMHGDYEAQRHWQEITVNLAVGEWYTNSSNNDLQYWGLDYPPLTAYHSYLVGRIGASIDPRFVELHKSRGFES--KEHKRFMRATVVSADVLIYLPAMLLLAYSLDKAFR--SDDKLFLFTLVAAYPGQTLIDNGHFQYNNISLGFAAVAIAAILRRRFYAAAFFFTLALNYKQMELYHSLPFFAFLLGECVSQKSFASFIAEISRIAAVVLGTFAILWVP--WLGS-LQAVLQVLHRLFPVARGVFEDKVANVWCAVNVVWKLKKHISNDQMALVCIACTLIASLPTNVLLFRRRTNVGFLLALFNTSLAFFLFSFQVHEKTILLTALPALFLLK----CWPDEMILFLEVTVFSMLPLLARDELLVPAVVATVAFHLIFKCFDSKSKLSNEYPLKYIAN-------------------------ISQILMISVVVASLTVPAPTKYPDLWPLIISVTSCGHFFLFFLWGNVQQFSSKLS--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12001-1", "uniprot_id": "ALG6_YEAST", "id": "Q12001-1", "name": "Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "MAIGKRLLVNKPAEESFYASPMYDFLYPFRPVGNQWLPEYIIFVCAVILRCTIGLGPYSGKGSPPLYGDFEAQRHWMEITQHLPLSKWYWY----DLQYWGLDYPPLTAFHSYLLGLIGSFFNPSWFALEKSRGFESPDNGLKTYMRSTVIISDILFYFPAVIYFTKWLGRYRNQSPIGQSIAASAILFQPSLMLIDHGHFQYNSVMLGLTAYAINNLLDEYYAMAAVCFVLSICFKQMALYYAPIFFAYLLSRSLLFPKFN--IARLTVIAFATLATFAIIFAPLYFLGGGLKNIHQCIHRIFPFARGIFEDKVANFWCVTNVFVKYKERFTIQQLQLYSLIATVIGFLPAMIMTLLHPKKHLLPYVLIACSMSFFLFSFQVHEKTILIPLLPITLLYSSTDWNVLSLVSWINNVALFTLWPLLKKDGLHLQYAVSFLLSNWLIGNFSFITPRFLPKSLTPGPSISSINSDYRRRSLLPYNVVWKSFIIGTYIAMGFYHFLDQFVAPPSKYPDLWVLLNCAVGFICFSIFWLWSYYKIFTSGSKSMKDL---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . : * : ..**:.**:****** *:* :*.: :** :* ***********:** . :. ::* :. *. ***:** : * :**:**: :* *:*.**:: : . : : *. *** ******.: **:: .: : .:. * *:: :*** **:: **.:**.... : :: .: :* : : * :: : * ::*:**. **:******* ** **. * * :. . .: *.: **: : : . : .*. :::***********:**: ** :: . : .: *:: *** :* * : .*: : * . : : * . : .* * ***: :: . . * * :: : . ", "identical_positions": 126, "similar_positions": 125, "identity": "22.78%" }, { "cls_id": "homologset.agr.SGD:S000005529", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80W65-1", "uniprot_id": "PCSK9_MOUSE", "id": "Q80W65-1", "name": "Proprotein convertase subtilisin/kexin type 9", "aln": "------MGTHCSAWLRWPLLPLLPPLLLLLLLLCPTGAGAQ-DEDGDYEELMLALPSQEDGLADEAAHVATATFRRCSKEAWRLPGTYIVVLMEETQRL----QIEQTAHRLQTRAARRGYVIKVLHIFYD--LFPGFLVKMSSDLLGLALKLPHVEYIEEDSFVFAQS------IPWNLERIIP----AWHQTEEDRSPDGSSQ-VEVYLLDTSIQGAHREIEGRVTITDFNSVPEEDGTRFHRQASKCDSHGTHLAGVVSGRDAGVAKGTSLHSLRVLNCQGKGTVSGTLIGLEFIRKSQLIQPSGP------LVVLLPLAGGYSRILNAACRHLARTGVVLVAAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGKDIIGASSDCSTCFMSQSGTSQAAAHVAGIVARMLSREPTLTLAELRQRLIHFSTKDVINMAWFPEDQQVLTPNLVATLPPSTHETGGQLLCRTVWSAHSGPTRTATATARCAPEEELLSCSSFSRSGRRRGDWIEAIGGQQVCKALNAFGGEGVYAVARCCLVPRANCSIHNTPAARAGLETHVHCHQKDHVLTGCSFHWEVEDLSVRRQPALRSRRQPGQCVGHQAASVYASCCHAPGLECKIKEHGISGPSEQVTVACEAGWTLTGCNVLPGASLTLGAYSVDNLCVARVHDTARADRTSGEATVAAAICCRSRPSAKASWVQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P59996-1", "uniprot_id": "PCSK9_RAT", "id": "P59996-1", "name": "Proprotein convertase subtilisin/kexin type 9", "aln": "------MGIRCSTWLRWPLS----PQLLLLLLLCPTGSRAQ-DEDGDYEELMLALPSQEDSLVDEASHVATATFRRCSKEAWRLPGTYVVVLMEETQRL----QVEQTAHRLQTWAARRGYVIKVLHVFYD--LFPGFLVKMSSDLLGLALKLPHVEYIEEDSLVFAQS------IPWNLERIIP----AWQQTEEDSSPDGSSQ-VEVYLLDTSIQSGHREIEGRVTITDFNSVPEEDGTRFHRQASKCDSHGTHLAGVVSGRDAGVAKGTSLHSLRVLNCQGKGTVSGTLIGLEFIRKSQLIQPSGP------LVVLLPLAGGYSRILNTACQRLARTGVVLVAAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGKDIIGASSDCSTCYMSQSGTSQAAAHVAGIVAMMLNRDPALTLAELRQRLILFSTKDVINMAWFPEDQRVLTPNRVATLPPSTQETGGQLLCRTVWSAHSGPTRTATATARCAPEEELLSCSSFSRSGRRRGDRIEAIGGQQVCKALNAFGGEGVYAVARCCLLPRVNCSIHNTPAARAGPQTPVHCHQKDHVLTGCSFHWEVENLRAQQQPLLRSRHQPGQCVGHQEASVHASCCHAPGLECKIKEHGIAGPAEQVTVACEAGWTLTGCNVLPGASLPLGAYSVDNVCVARIRDAGRADRTSEEATVAAAICCRSRPSAKASWVHQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NBP7-1", "uniprot_id": "PCSK9_HUMAN", "id": "Q8NBP7-1", "name": "Proprotein convertase subtilisin/kexin type 9", "aln": "------MGTVSSRRSWWPLP----LLLLLLLLLGPAGARAQEDEDGDYEELVLALRSEEDGLAEAPEHGTTATFHRCAKDPWRLPGTYVVVLKEETHLS----QSERTARRLQAQAARRGYLTKILHVFHG--LLPGFLVKMSGDLLELALKLPHVDYIEEDSSVFAQS------IPWNLERITP----PRYRADEYQPPDGGSL-VEVYLLDTSIQSDHREIEGRVMVTDFENVPEEDGTRFHRQASKCDSHGTHLAGVVSGRDAGVAKGASMRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGP------LVVLLPLAGGYSRVLNAACQRLARAGVVLVTAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSQSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVINEAWFPEDQRVLTPNLVAALPPSTHGAGWQLFCRTVWSAHSGPTRMATAVARCAPDEELLSCSSFSRSGKRRGERMEAQGGKLVCRAHNAFGGEGVYAIARCCLLPQANCSVHTAPPAEASMGTRVHCHQQGHVLTGCSSHWEVEDLGTHKPPVLRPRGQPNQCVGHREASIHASCCHAPGLECKVKEHGIPAPQEQVTVACEEGWTLTGCSALPGTSHVLGAYAVDNTCVVRSRDVSTTGSTSEGAVTAVAICCRSRHLAQASQELQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25036-1", "uniprot_id": "YSP3_YEAST", "id": "P25036-1", "name": "Subtilisin-like protease 3", "aln": "MKFSTILPILWANCCLCMIIPDFDGIVRFIENIDGTRSVRAGEGLGQHDPGNFHTEHQHVAHKTEFLPYRYVIVFNEDISLQQIQSHMQVVQKDHSTSVGKLTENDAFWRVISSSVSSKSQFGGIDNFFDINGLFRGYTGYFTDEIIKIISQDPIIKFVEQETTVKISNSSLQEEAPWGLHRVSHREKPKYGQDLEYLYEDAAGKGVTSYVLDTGIDTEHEDFEGRAEWG--AVIPAND------EASDLNGHGTHCAGIIGSKHFGVAKNTKIVAVKVLRSNGEGTVSDVIKGIEYVTKEHIESSKKKNKEFKGSTANLSLGSSKSLAMEMAVNAAVDSGVHFAIAAGNEDEDACLSSPAGAEKSITVGASTFSDD----RAFFSNWGTCVDVFAPGINIMSTYIGSRNATLSLSGTSMASPHVAGILSYFLSLQPAP------------------DSEFFNDAP--------------------------------------------SPQELKEKVLKFSTQG-----VLGDIGDDTPNKLIYNGGGKKLDGFW------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : :: : : : : *::: : :. . . . . . :: . ** :.: : : : :.: .: :. . : :.* *: *: ::.::: : : * :.::*::: * .. **.*.*: : * *... * *:***.*: *.::***. :* :* :**. :.**** **::..:. ****.:.: :::**..:*:****..: *:*:: *.:: .. .. *.*... * :: * . . :** :. **** :**** ***.* : *****:. .*: :: :*:* ***:**** :*:.: .. .. :* **** *:.***** : :*. :* : :* : :*:* . .** .* : *.. : **: : .. ", "identical_positions": 105, "similar_positions": 164, "identity": "14.48%" }, { "cls_id": "homologset.agr.SGD:S000005530", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABZ3NNK7-1", "uniprot_id": "A0ABZ3NNK7_RAT", "id": "A0ABZ3NNK7-1", "name": "rRNA-processing protein UTP23 homolog", "aln": "MKITRQKHAKKHLGFFRNNFGVREPYQILLDGTFCQAALRGRIQLRDQLPRYLMGETQLCTTRCVLKELETLGKELYGAKLIAQKCQVRNCPH-FKSAVSGSECLLSMVDDG--NPHHYFVAT---------------------QNTIVLDKPSPRTVAFVKAVEAGQLVSVHEKQSIKELKEEQGLVRNPELRKRR-KKKKVGGPNPLSCLKKKKK---AQDTKSPASEKKRKRKRIRIRNKSTPKVS-AQQGAEG--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CX11-1", "uniprot_id": "UTP23_MOUSE", "id": "Q9CX11-1", "name": "rRNA-processing protein UTP23 homolog", "aln": "MKITRQKHAKKHLGFFRNNFGVREPYQILLDGTFCQAALRGRIQLRDQLPRYLMGETQLCTTRCVLKELETLGKELYGAKLIAQKCQVRNCPH-FKSPVSGSECLLSMVDEG--NPHHYFVATQDQNLSVKVKRTPGIPLMFIIQNTIVLDKPSPRTVAFVKAVEAGQLVSVHEKQSIKQLKEEQGLVRNPDLRRRRRKKKKVGGPNPLSCLKKKKK---AQDTKSPASEKKRKRK--RIRNRSTLKVSSEQQGAEG--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BRU9-1", "uniprot_id": "UTP23_HUMAN", "id": "Q9BRU9-1", "name": "rRNA-processing protein UTP23 homolog", "aln": "MKITRQKHAKKHLGFFRNNFGVREPYQILLDGTFCQAALRGRIQLREQLPRYLMGETQLCTTRCVLKELETLGKDLYGAKLIAQKCQVRNCPH-FKNAVSGSECLLSMVEEG--NPHHYFVATQDQNLSVKVKKKPGVPLMFIIQNTMVLDKPSPKTIAFVKAVESGQLVSVHEKESIKHLKEEQGLVKNTEQSRRK-KRKKISGPNPLSCLKKKKK---APDTQSSASEKKRKRK--RIRNRSNPKVLSEKQNAEGE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQ40-1", "uniprot_id": "Q9VQ40_DROME", "id": "Q9VQ40-1", "name": "rRNA-processing protein UTP23 homolog", "aln": "MKISRFKKSHKTLVFFASNFDYREPYQVLIDATFCQAALQQKIGIDEQIKKYFQCGVKLLTTQCVILESESLGAPLTGATSIVKRFHVHKCGH-EGKPVPASECIKSMTKD-----NRYVVASQDRLLQESLRKIPGRCLLYLHKATPVLEAPSKASKKWVQRR-AKNLMLGKQVEKIDYMKEKQGLKPAETAVKPK-KHKGPKNPNPLSCKKSKKD---KAKQQLKGVEQTAITK----AKRKRVKIPAHVKAALGKD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12339-1", "uniprot_id": "UTP23_YEAST", "id": "Q12339-1", "name": "rRNA-processing protein UTP23", "aln": "MRQKRAKSYRKQLLVYSHTFKFREPYQVLVDNQLVLECNNSNFNLPSGLKRTLQADVKVMITQCCIQALYETRND--GAINLAKQFERRRCNHSFKDPKSPAECIESVVNISGANKHRYVVASQDIDLRRKLRTVPGVPLIHLTRSVMVMEPLSTASAKASKITEEQKLYKGLNDPNIEKLQESGDGSGKESITKKR--KLGPKAPNPLSVKKKKKVNSPSDEVKDKEDTSKEKKKRRRRKHKSNTNVPVSNGTTAAQ-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .* * :* * .: .* *****:*:* : . . .: : . : : : .:: *:* : ** :.:: . :.* * .. . :**: *:.. ::*.**: : . *:: * : : :* : .*. ::*. . : : : ***** *.** . : .. * ::. :: : . ", "identical_positions": 39, "similar_positions": 71, "identity": "15.06%" }, { "cls_id": "homologset.agr.SGD:S000005531", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A0U6-1", "uniprot_id": "D4A0U6_RAT", "id": "D4A0U6-1", "name": "DNA ligase", "aln": "-----MASSQASRTVAAHVPFADLCSTLERIQKGKDRAEKIRHFKEFLDSWRKFHDALHKNK-------KDVPDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPREGKDAQKLLNYRTPSGARSDAGDFATIAYFVLKPRCLQK-GSLTIQKVNELLDLVASN----NSGKRKDLVKKSLLQLITQCSALEQKWLIRMIIKDLKLGVSQHTILSIFHNDAVELHNVTTDLEKVCRQLHDPSVGLSDIS----------ITLFSAFRPMLAAVADVER-----VEKDMKQQSFYIETKLDGERMQMHKD--GALYRYFSRNGYNYTDQFGESPQEGSLTPFIHNAFKTDVQVCILDGEMMAYNPTTQTFM----QKGVKFDIKRMV--EDSDLQTCYCVFDVLMVNNKKLGRETLRKRYDILSSTFTPIQGRIEIVQKTQAQTKQEVVDALNDAIDKREEGIMVKHPLSIYKP-DKRGEGWLKIKPEYVTGLMDELDLLIVGGYWGKGSRGGMMSHFLCAVAETPPPG-------------------DKPSVFHTLCRVGSGYTMKELYDLGLKLAKYWKPFQRKSPPSCILCGTEK----PEVYIEPQNSVIVQIKAAEIVPSDM----YKTGSTLRFPRIEKIRDDKEWHDCMTLDDLEQLRG-KASGKLATKHLHIGDDDEPREKRRKPISKTKKTIGIIEHLKAPNLSNINKVSNVFEDVEFCVMSGLDG------YPKPDLENKIAEFGGYIVQNPGPD-----TYCVIAGSENIRVRNIISSD--RHDVVKPEWLLECFKTKTCVPWQPRFMIHMCPSTKQHFAREYDCYGDSYFVDAD-LDQLKEVFLRIKPSEQQTPEEMAPVIADLECRYSWDHSPLSMFRHYTVYLDLYAVINDLSSKIEATRLGVTALELRFRGAKVVSRLSEGVSHVIIGEDQRRVSDFKTFRRTLKKKF-----------KILQERWVIDSVDKCELQEENLYLL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BTF7-1", "uniprot_id": "DNLI4_MOUSE", "id": "Q8BTF7-1", "name": "DNA ligase 4", "aln": "-----MASSQTSQTVAAHVPFADLCSTLERIQKGKDRAEKIRHFKEFLDSWRKFHDALHKNR-------KDVTDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPREGKDAQKLLNYRTPSGARTDAGDFAMIAYFVLKPRCLQK-GSLTIQQVNELLDLVASN----NSGKKKDLVKKSLLQLITQSSALEQKWLIRMIIKDLKLGISQQTIFSIFHNDAVELHNVTTDLEKVCRQLHDPSVGLSDIS----------ITLFSAFKPMLAAVADVER-----VEKDMKQQSFYIETKLDGERMQMHKD--GALYRYFSRNGYNYTDQFGESPQEGSLTPFIHNAFGTDVQACILDGEMMAYNPTTQTFM----QKGVKFDIKRMV--EDSGLQTCYSVFDVLMVNKKKLGRETLRKRYEILSSTFTPIQGRIEIVQKTQAHTKKEVVDALNDAIDKREEGIMVKHPLSIYKP-DKRGEGWLKIKPEYVSGLMDELDVLIVGGYWGKGSRGGMMSHFLCAVAETPPPG-------------------DRPSVFHTLCRVGSGYTMKELYDLGLKLAKYWKPFHKKSPPSSILCGTEK----PEVYIEPQNSVIVQIKAAEIVPSDM----YKTGSTLRFPRIEKIRDDKEWHECMTLGDLEQLRG-KASGKLATKHLHVGDDDEPREKRRKPISKTKKAIRIIEHLKAPNLSNVNKVSNVFEDVEFCVMSGLDG------YPKADLENRIAEFGGYIVQNPGPD-----TYCVIAGSENVRVKNIISSD--KNDVVKPEWLLECFKTKTCVPWQPRFMIHMCPSTKQHFAREYDCYGDSYFVDTD-LDQLKEVFLGIKPSEQQTPEEMAPVIADLECRYSWDHSPLSMFRHYTIYLDLYAVINDLSSRIEATRLGITALELRFHGAKVVSCLSEGVSHVIIGEDQRRVTDFKIFRRMLKKKF-----------KILQESWVSDSVDKGELQEENQYLL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49917-1", "uniprot_id": "DNLI4_HUMAN", "id": "P49917-1", "name": "DNA ligase 4", "aln": "-----MAASQTSQTVASHVPFADLCSTLERIQKSKGRAEKIRHFREFLDSWRKFHDALHKNH-------KDVTDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTPTGTHGDAGDFAMIAYFVLKPRCLQK-GSLTIQQVNDLLDSIASN----NSAKRKDLIKKSLLQLITQSSALEQKWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVCRQLHDPSVGLSDIS----------ITLFSAFKPMLAAIADIEH-----IEKDMKHQSFYIETKLDGERMQMHKD--GDVYKYFSRNGYNYTDQFGASPTEGSLTPFIHNAFKADIQICILDGEMMAYNPNTQTFM----QKGTKFDIKRMV--EDSDLQTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQKTQAHTKNEVIDALNEAIDKREEGIMVKQPLSIYKP-DKRGEGWLKIKPEYVSGLMDELDILIVGGYWGKGSRGGMMSHFLCAVAEKPPPG-------------------EKPSVFHTLSRVGSGCTMKELYDLGLKLAKYWKPFHRKAPPSSILCGTEK----PEVYIEPCNSVIVQIKAAEIVPSDM----YKTGCTLRFPRIEKIRDDKEWHECMTLDDLEQLRG-KASGKLASKHLYIGGDDEPQEKKRKAAPKMKKVIGIIEHLKAPNLTNVNKISNIFEDVEFCVMSGTDS------QPKPDLENRIAEFGGYIVQNPGPD-----TYCVIAGSENIRVKNIILSN--KHDVVKPAWLLECFKTKSFVPWQPRFMIHMCPSTKEHFAREYDCYGDSYFIDTD-LNQLKEVFSGIKNSNEQTPEEMASLIADLEYRYSWDCSPLSMFRRHTVYLDSYAVINDLSTKNEGTRLAIKALELRFHGAKVVSCLAEGVSHVIIGEDHSRVADFKAFRRTFKRKF-----------KILKESWVTDSIDKCELQEENQYLI---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B636-1", "uniprot_id": "A0ACD6B636_DANRE", "id": "A0ACD6B636-1", "name": "DNA ligase", "aln": "MESVSKSDAKPQAFVAAQVPFIHLCTVLEKIQKTKLRPDKSKILKEFIDSWRNFHAALHKDN-------PDTADSFYAAMRLIVPSFERERMAYGIKENMLAKLYIEVLGLPKNGDEANKLLNYRAPTTSQGEAGDFALMAYFVLKKRCTSQ-GNLSIKEVNDFLDSVAIN----NASKQKDQVKKSLLYLITQSSALEQKWLIRMILKDMKLGISKETVLQVFHPDAPEFYNVTTDLNKVCRQLHDPSVSLSEVS----------IDLFSAFKPMLAAVANIRQ-----IEKQMGNRPFYIETKLDGERIQLHKA--GDVYKYYTRNSYEYTQQFGASPLEGSLTPYIHNVFSPHVVNCILDGEMMAYNPKTETFM----QKGSKFDIKRLV--DDSDLQTCFCVFDVLLINNQKFGKEPLKKRYESLETVFSPIKGRIHLVSKSEGRTMQEVVNSLNEAIDNREEGIMVKDPMSIYKP-DKRGEGWLKIKPEYVDGLMDELDLLIVGGYWGKGRRSGMLSHFLCAVAEVPSPG-------------------EKPTVFHTLCRIGSGYTLKELYDLGVKLAKHWKVYNKNNPPAAILCGTEK----PEVYIEPRNSVILQVKAAEIVTSEM----YKTDCTLRFPRIERIREDKEWHQCMTLDDLNQFRS-KASGKLASRHLNIHED-QPEKKKRKIVAKPKKTIGVIDHFKSQDLSKVAKETDMFEEVEFCVINGDDE------HSKAELEKGVARCGGIVVQNPGKD-----TYCAIAAVQNMRVKNLISSD--QHDVVWATWLLECLENKQVIPWQPRHMIHMSPSTREHFAKEYDQYGDSYYVDTS-EQQLRDVIERISSAEVKS-----LSVAQIEAENAWDDLPTSIFRPYSAYFDRCADIGDPKSVICGMCLDTRALEFRFHGGKVVEKLKEGISHVVV-EDMKRALDLKTLRRLHAKKF-----------KIVHESWVTDSIKAGHVKDEIDYLI---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYA5-1", "uniprot_id": "Q9VYA5_DROME", "id": "Q9VYA5-1", "name": "DNA ligase 4", "aln": "----------MSVDIASTIKFRDICSLFEKIKATQKVANKEEVLKSYYESFCRHRESFRRQTGLNNDQPEDGASSFYSVLRLLLPGADTGRDTYGLQITALGRLYIRVLQLPTDSSDAIRLQHRNGNMYR-----DYGDVVYSVLKPRCFNPPSNLRLKEIHQMLDTIANE----DTEVKQ----QQLIRFTEQASPEEQKWLIRLLLKSLGLGIGEQKIFGVLHPKAQDIYQRCSDLGHVCNLLADRTTDLDASSSKDSKAAVKFVNLNSVIRPFHQIRPMLCERFPGDIQELMQSDVLYLETKMDGERFQLHID--RGRFMYISRNGVDYTRNFGHSYDHGTLTPKLRGLLPLGLESIILDGEMMVWDTNKLRFR----EKGENTDVKSLK--PEGSWQPCFVVYDLLYFNGQSLLDHTYIQRAYKLQKLIVEQSGVLQLMRARKIGSVQEFNELFQQALDSHAEGIVLKKQGSRYQPGVRLGGGWYKDKADYIKGLITEFDVLIIGAFYNR--KRTFVDSFLLGVLQPAPPGSS-----------------NRPEVFSIGVVANN---TKQRGVLNHTLKPHWHDVVNEPPPLWFHYKPKERSGCPDLWIEPQNSVILQVKAADLAPNGA----FFTRKSLHFPRTEMKRDDKTWSECMTLKEFNDLCGGPLAIKKLNKRQLRLEDVTTKRKQMRMTPSERSRLGLAVYEKRYDASTSASTSKLFDGLSFCILSGSAGR-----HSKHQLQELAVKNGGCIVENPLPNDP---KCFCIAGDETFLVKRLILQQPRTCDIVRMEWLLRVCQ-KQELELKPRDLIAATEPLQQDLAECFDRHGDSYTKDIANVEELQDLLQGIELTADNVAGITASNLNALEDQLLDGKKNLNMFRNLNAFFYS------------PHGDEVAKLLFLQNGGRIVDDSDPQLNLGFICMSSDIDNDHFEHWLHNHSKLTTD--------KVLNSAWIHQCHREGILLPMHSFV----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08387-1", "uniprot_id": "DNLI4_YEAST", "id": "Q08387-1", "name": "DNA ligase 4", "aln": "-MISALDSIPEPQNFAPSPDFKWLCEELFVKIHEVQINGTAGTGKSRSFKYYEIISNFVEMWR------KTVGNNIYPALVLALP--YRDRRIYNIKDYVLIRTICSYLKLPKNSATEQRLKDWKQRVGKGGN--LSSLLVEEIAKRRAEPSSKAITIDNVNHYLDSLSGDRFASGRGFKSLVKSKPFLHCVENMSFVELKYFFDIVLKNRVIGGQEHKLLNCWHPDAQDYLSVISDLKVVTSKLYDPKVRLKDDD--------LSIKVGFAFAPQLAKKVNLSY----EKICRTLHDDFLVEEKMDGERIQVHYMNYGESIKFFSRRGIDYTYLYGASLSSGTISQHLR--FTDSVKECVLDGEMVTFDAKRRVILPFGLVKGSAKEALSFNSINNVDFHPLYMVFDLLYLNGTSLTPLPLHQRKQYLNSILSPLKNIVEIVRSSRCYGVESIKKSLEVAISLGSEGVVLKYYNSSYNV-ASRNNNWIKVKPEYLEEFGENLDLIVIGRDSGKKDSFMLGLLVLDEEEYKKHQGDSSEIVDHSSQEKHIQNSRRRVKKILSFCSIANGISQEEFKEIDRKTRGHWKRTSEVAPPASILEFGSK---IPAEWIDPSESIVLEIKSRSLDNTETNMQKYATNCTLYGGYCKRIRYDKEWTDCYTLNDLYESRT-----------VKSNPSYQAERSQLGLIRKKRKRVLISDSFHQN--RKQLPISNIFAGLLFYVLSDYVTEDTGIRITRAELEKTIVEHGGKLIYNVILKRHSIGDVRLISCKTTTECKALIDRG---YDILHPNWVLDCIAYKRLILIEPNYCFNVSQKMRAVAEKRVDCLGDSFENDIS----------ETKLSSLYKSQLSLPPMGELEIDSEVRRFPLFLFSNRIAYVPR---------RKISTEDDIIEMKIKLFGGKITDQQSLCNLIIIPYTDPILRKDCMNEVHEKIKEQIKASDTIPKIARVVAPEWVDHSINENCQVPEEDFPVVNY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*. * :* : . :. .: . : . ..:*..: * :* * *.:: * : * ** :. :* . . . :. : * *. : :.:::. ** :: : . :. : :: : * * *::: :::*. :* :..:: * .* : . :** * * * .. *. . : : .: * : : :* *:****:*:* : :*.. :** :* * *::: :: : : :*****:.::.. : ** : : : . :. : *:*:* .* .: . :* *.. : . :.:: . :.. . :: *:. **:::* * *: . .* * *.:*: : ::*::::* .: : .* * : : . :: :. . :*: . ** : .: * :*:* :*:::::*: .: . : * :* : * ** * :* ** :: : . ....: . :. : : : . :.:* : * ::.. .: :*:: .. ** :: * . *: . : :* *:: *:* * : :*. : : . * ***: * . : : :* :* :. : : *.::.. . . * : ::: *: .. : ", "identical_positions": 112, "similar_positions": 255, "identity": "11.11%" }, { "cls_id": "homologset.agr.SGD:S000005532", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A6X9-1", "uniprot_id": "D4A6X9_RAT", "id": "D4A6X9-1", "name": "18S rRNA aminocarboxypropyltransferase", "aln": "MGRKKVARGSKTEGGRVRRPPG-----RSLDAFAEEVGAALRASVQTEEAE--NQSGPDPAALP--CALAMWELGHCDPKRCTGRKLARLGLVRCLRLSQRFGGLVLSPVGTQYVSPADRTYPTLFDRQLVAQSGIAVIDCSWAKLDETPFGKMRGSHLRLLPYLVAANPVNYGRPCKLSCVEAFAAAFCIVGFSDLAVILLRKFKWGKGFLDLNRQLLDKYAACCGPEEVLEAEQGYLASTKDTPEEENIDPFDVDSGREFANLNRPVASTRLPMDTDDTDESEDHSEDSGEDSDECEEQGPGANGGDSSYSQAEEIPEQE--AQARDSTEIWKGIKKRQRD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5HZH2-1", "uniprot_id": "TSR3_MOUSE", "id": "Q5HZH2-1", "name": "18S rRNA aminocarboxypropyltransferase", "aln": "MGRKKVARGSRKESGRVRRPSG-----RSLDAFAEEVGAALRASVQPEEAE--DQGGPGPAALP--CALAMWELGHCDPKRCTGRKLARLGLVRCLRLSQRFGGLVLSPVGTEYVSPADR--------QLVAQSGVAVIDCSWAKLDDTPFQKMRGSHLRLLPYLVAANPVNYGRPCKLSCVEAFAAAFCIVGFSDLAVILLRKFKWGKGFLDLNRELLDKYAACRGPEEVLQAEQGYLASTRDTPEED-IDPFDVDSGREFVNLNRPVASTRLPEDMDDTDGSEEHSEDSEEDSDECEEPGPGANGGDSNYSGAEETPEQE--AQARDSTEIWKGIKKRQRD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJK0-1", "uniprot_id": "TSR3_HUMAN", "id": "Q9UJK0-1", "name": "18S rRNA aminocarboxypropyltransferase", "aln": "MGRRRAARGPGAEGGRPRHLPT-----RSLEAFAEEVGAALQASVEPGAAD--GEGGPGPAALP--CTLAMWELGHCDPRRCTGRKLARLGLVRCLRLGHRFGGLVLSPVGKQYASPADR--------QLVAQSGVAVIDCSWARLDETPFGKMRGSHLRLLPYLVAANPVNYGRPYRLSCVEAFAATFCIVGFPDLAVILLRKFKWGKGFLDLNRQLLDKYAACGSPEEVLQAEQEFLANAKESPQEEEIDPFDVDSGREFGNPNRPVASTRLPSDTDDSDASE--------------DPGPGAERGGASSSCCEEEQTQGRGAEARAPAEVWKGIKKRQRD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFA0-1", "uniprot_id": "Q9VFA0_DROME", "id": "Q9VFA0-1", "name": "18S rRNA aminocarboxypropyltransferase", "aln": "MSGRNRGKGKKGGGGPYRNVKANHNCARSFAQQANELASSSSSENESSDSESSGDGAQNDLGQPPEFAVAMWDLNHCDPKKCSGRKLARLGLISNLRLGQKFPGLVLSPVGQLCVSPLDR--------DVVASSGVAVIDCSWAKLDETPFGRMRSPHPRLLPFLVAANPINYGKPCKLSCVEAIAATLYICGFTEEARWFLGKFSWGHAFLELNDKLLNAYAACKSSDEIVKVQNEYLEKEQQ----------ERDKPRDLRDFY-PTSSS-------------------------------------SSSSETETEGDDE-------------DTKAKPKN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12094-1", "uniprot_id": "TSR3_YEAST", "id": "Q12094-1", "name": "18S rRNA aminocarboxypropyltransferase", "aln": "MGKGKNKMHEPKNGRPQRGANG-----------HSSRQNHRRMEMKYDNSE--------KMKFP--VKLAMWDFDHCDPKRCSGKKLERLGLIKSLRVGQKFQGIVVSPNGKGVVCPDDL--------EIVEQHGASVVECSWARLEEVPFNKIGGKHERLLPYLVAANQVNYGRPWRLNCVEALAACFAIVGRMDWASELLSHFSWGMGFLELNKELLEIYQQCTDCDSVKRAEEEWLQKLEKETQERKSRAKEEDIWMMGNINRRGNGSQSDTSESEENSEQSDLEGNNQCIEYDSLGNAIRIDNMKSREAQSEESEDEESGSKENGEPLSYDPLGNLIR-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . . * .. . : :: * :***::.****::*:*:** ****: **:.::* *:*:** * ..* * ::* . * :*::****:*::.** :: . * ****:***** :***:* :*.****:** : * * : * :* :*.** .**:** :**: * * . :.: ..:: :* . .. : * .* : : * : : ", "identical_positions": 78, "similar_positions": 72, "identity": "22.74%" }, { "cls_id": "homologset.agr.SGD:S000005533", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VD33-1", "uniprot_id": "SGTB_MOUSE", "id": "Q8VD33-1", "name": "Small glutamine-rich tetratricopeptide repeat-containing protein beta", "aln": "--MSSVKPLVYAVIRFLREQSQMDAYTSDEQESLEVAIQCLETVFKISPEDTHLAVS------QPLTEMFTNSVCKN------DIRPLSNSVP---------------------EDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVTSYQKALDLDPEND------SYKSNLKIAEQKLREVSSPTGTGLSFDMASLINN-----PAFITMAAS----LMQNPQVQQLMSGMMT-----NAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQLRNH-IRSRSFSSSADEHS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q80W98-1", "uniprot_id": "SGTB_RAT", "id": "Q80W98-1", "name": "Small glutamine-rich tetratricopeptide repeat-containing protein beta", "aln": "--MSSVKPLVYAVIRFLREQSQMDAYTSDEQESLEVAIQCLETVFKISPEDTHLAVS------QPLTEMFTNSVCKN------DIRPLSNSVP---------------------EDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVTSYQKALDLDPEND------SYKSNLKIAEQKLREVSSPTGTGLTFDMASLINN-----PAFITMAAS----LMQNPQVQQLMSGMMT-----NAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQLRNH-IRSRSFSSSTEEHS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96EQ0-1", "uniprot_id": "SGTB_HUMAN", "id": "Q96EQ0-1", "name": "Small glutamine-rich tetratricopeptide repeat-containing protein beta", "aln": "--MSSIKHLVYAVIRFLREQSQMDTYTSDEQESLEVAIQCLETVFKISPEDTHLAVS------QPLTEMFTSSFCKN------DVLPLSNSVP---------------------EDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPEND------SYKSNLKIAEQKLREVSSPTGTGLSFDMASLINN-----PAFISMAAS----LMQNPQVQQLMSGMMT-----NAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQLRNH-IRSRSFSSSAEEHS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BJU0-1", "uniprot_id": "SGTA_MOUSE", "id": "Q8BJU0-1", "name": "Small glutamine-rich tetratricopeptide repeat-containing protein alpha", "aln": "--MDNRKRLAYAIIQFLHGQLRHGGLSCDAQESLEVAIQCLETAFGVTLEDSDLALP------QTLPEIFEAATSSKQ-EMPQDPRAPDRTPPSE-------------------EDSAEAERLKTEGNEQMKLENFEAAVHLYGKAIELNPANAVYFCNRAAAYSKLGNYVGAVQDCERAIGIDPGYSKAYGRMGLALSSLNKHAEAVAYYKKALELDPDND------TYKSNLKIAELKLREAPSPTGGVGSLDIAGLLNN-----PHFITMASS----LMNSPQLQQLMSGMISG--GHNPLGTPGSSPQ-QSDLASLIQAGQQFAQQMQQQNPEFVEQIRSQVVRSRTPSASHEEQQE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70593-1", "uniprot_id": "SGTA_RAT", "id": "O70593-1", "name": "Small glutamine-rich tetratricopeptide repeat-containing protein alpha", "aln": "--MDNRKRLAYAIIQFLHGQLRHGGLSSDAQESLEVAIQCLETAFGVTLEDSDLALP------QTLPEIFEAATASK--EMPQDPRGPDRTPPSE-------------------EDSAEAERLKTEGNEQMKLENFEAAVHLYGKAIELNPANAVYFCNRAAAYSKLGNYVGAVQDCERAIGIDPGYSKAYGRMGLALSSLNKHAEAVAYYKKALELDPDND------TYKSNLKIAELKLREAPSPTGGVGSLDIAGLLNN-----PHFITMASS----LMNSPQLQQLMSGMISG--GHNPLGTPGSSPQ-HSDLASLIQAGQQFAQQMQQQNPEFVEQIRSQVVRSRTPSASHEEQQE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43765-1", "uniprot_id": "SGTA_HUMAN", "id": "O43765-1", "name": "Small glutamine-rich tetratricopeptide repeat-containing protein alpha", "aln": "--MDNKKRLAYAIIQFLHDQLRHGGLSSDAQESLEVAIQCLETAFGVTVEDSDLALP------QTLPEIFEAAATGK--EMPQDLRSPARTPPSE-------------------EDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNE------TYKSNLKIAELKLREAPSPTGGVGSFDIAGLLNN-----PGFMSMASN----LMNNPQIQQLMSGMISG--GNNPLGTPGTSPS-QNDLASLIQAGQQFAQQMQQQNPELIEQLRSQ-IRSRTPSASNDDQQE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12118-1", "uniprot_id": "SGT2_YEAST", "id": "Q12118-1", "name": "Small glutamine-rich tetratricopeptide repeat-containing protein 2", "aln": "-MSASKEEIAALIVNYFSSIVEKKEISEDGADSLNVAMDCISEAFGFEREAVSGILGKSEFKGQHLADILNSASRVPESNKKDDAENVEINIPEDD-----------------AETKAKAEDLKMQGNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKKVLDIEGDNATEAMKRDYESAKKKVEQSLNLEKTVPEQSRDADVDASQGASAGGLPDLGSLLGGGLGGLMNNPQLMQAAQKMMSNPGAMQNIQKMMQDPSIRQMAEGFASGGGTPNLSDLMNNPALRNMAGNLFGGAGAQSTDETPDNENKQ", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VJD4-1", "uniprot_id": "Q9VJD4_DROME", "id": "Q9VJD4-1", "name": "", "aln": "MPDAVQQSFVRSFIDYLKK--QGDVMSPDQTESIEVAIQCLQAAFDLGDDVEAAPAAAGE--EQATTQSSSTASAPDDDAVASGSAGIGAAAAAVPNNIDMFELFQSLYTERNPESLALAESIKNEGNRLMKENKYNEALLQYNRAIAFDPKNPIFYCNRAAAHIRLGENERAVTDCKSALVYNNNYSKAYCRLGVAYSNMGNFEKAEQAYAKAIELEPDNE------VYKSNLEAARNARNQP--PQTGRLREDLINMLSQ-----PMVRNLFNN------AEIDVEQLLSMLQNP-----MIMNTIRQQFGGGNAPTLPNDMVQMIYNMTSQLTGFPNSNANP--GNEQQPGNQPPPST---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. .: :: . : * :*::**::*:. .* . : * .: : . . * . *: :* :**. * :.: *: * .** . * *.:::.***** * . *: *.: *: : * :.* *:*.* .: :* * *.:::: :* *:* : .. . *: . * . .: . . :: * . : . : : . . : . : : . . . . ", "identical_positions": 42, "similar_positions": 88, "identity": "11.54%" }, { "cls_id": "homologset.agr.SGD:S000005540", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A6K6-1", "uniprot_id": "A0A8I6A6K6_RAT", "id": "A0A8I6A6K6-1", "name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRKKGSCLAPMTNPRRRRLVVRQVCKSSGQLEAQPPLGPGAARRRWRRDAERAECGRAEPEPERGRRSRAGCGPAEMPYKLKKDKEPPKLAKGTAKPSSSSK---DGGGENTDTEAQPQPQPQP--------PSSNKRPSNST------------------PPPTQLSKIKYSGGPQIVKKERR----------------------------------QSSSRFNLSKNR----ELQKLPALK-DSPTQEREELFIQKLRQCCVLFDFVSDPLSDLKFKEVKRAGLNEMVEYITHSRDVVTEAIYPEAVTMFSVNLFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLALLDLFDSEDPRERDFLKTILHRIYGKFLGLRAYIRRQINHIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKMFLIRVLLPLHKVKSLSVYHPQLAYCVVQFLEKESSLTEPVIVGLLKFWPKTHSPKEVMFLNELEEILDVIEPSEFSKVMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAARVLPIMFPALYRNS--------------------------KSHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQYKAEKQKGRFRMKEREEMWQKIEELARLNPQYPMFR---------APPPLPPVYSMETETPTAEDIQLLK---------RTVETEAVQMLKDIKKDKVLLRRKSELPQDVYTIKALEAHKRAEEFLTASQEAL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14738-1", "uniprot_id": "2A5D_HUMAN", "id": "Q14738-1", "name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPYKLKKEKEPPKVAKCTAKPSSSGK---DGGGENT-EEAQPQPQPQPQPQAQSQPPSSNKRPSNST------------------PPPTQLSKIKYSGGPQIVKKERR----------------------------------QSSSRFNLSKNR----ELQKLPALK-DSPTQEREELFIQKLRQCCVLFDFVSDPLSDLKFKEVKRAGLNEMVEYITHSRDVVTEAIYPEAVTMFSVNLFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLALLDLFDSEDPRERDFLKTILHRIYGKFLGLRAYIRRQINHIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKMFLIRVLLPLHKVKSLSVYHPQLAYCVVQFLEKESSLTEPVIVGLLKFWPKTHSPKEVMFLNELEEILDVIEPSEFSKVMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAARVLPIMFPALYRNS--------------------------KSHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQYKAEKQKGRFRMKEREEMWQKIEELARLNPQYPMFR---------APPPLPPVYSMETETPTAEDIQLLK---------RTVETEAVQMLKDIKKEKVLLRRKSELPQDVYTIKALEAHKRAEEFLTASQEAL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60996-1", "uniprot_id": "2A5G_MOUSE", "id": "Q60996-1", "name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLTCNKAGSGMVVDAAS------------------------------------SNGPFQP----------VALLHIR-DVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEAVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNS--------------------------KTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYAVYS---------QASAVSIPVAMETDGPQFEDVQMLK---------KTVSDEARQAQKELKKDRPLVRRKSELPQDPHTEKALEAHCRASELLSQDGR----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A0C3-1", "uniprot_id": "A0A8I6A0C3_RAT", "id": "A0A8I6A0C3-1", "name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLTCNKAGSGMVVDAAS------------------------------------SNGPFQP----------VALLHIR-DVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEAVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNS--------------------------KTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYAVYS---------QASAMSIPVAMETDGPQFEDVQMLK---------KTVSDETRQAQKDLKKDRPLVRRKSELPQDPHTEKALEAHCRASELLSQDGR----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13362-1", "uniprot_id": "2A5G_HUMAN", "id": "Q13362-1", "name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLTCNKAGSRMVVDAAN------------------------------------SNGPFQP----------VVLLHIR-DVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNS--------------------------KTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYS---------QASTMSIPVAMETDGPLFEDVQMLR---------KTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IN89-1", "uniprot_id": "Q8IN89_DROME", "id": "Q8IN89-1", "name": "", "aln": "MVFGAMLLTGNGLKGPKQQQQQHQQEPQQQQQQSQQQQQEQKKPAPIKSSSKEQETQPIAAGYYALGIRIPKSPSFHSGLDQLADDELDDQVQDQQQEQQQTGSRFRFSSVEELKAKFEGRKTPLSPPEAAAGGAAGSGAPTTSSSPSSSSTSSNSSASALSSLSQAASSSLASAAANSSASSSAATYGGGANSAAAALIASSPFGSQSSTSSLSLSSNAGMSKNAAGAGSGSGSGTTSTGAASGSNSLVSTLAQHFSAATSAAASAAAAAASSASAASSSSASSSSTATNNAASSSIAASKSPVSAAAAIKNILNATKSVGTSAAAAAAAAATSS---SSSPSSAAAVPSSAATAVAAVPTTSDVPAEEMRPTVAQNLVGGISISLGIGQRNGGAAPASSAVMVTPNATMVVTTSSLSIRQNGDILPGHPAGLQPSPQTLQQLTGSPGRARDRNLFYTPPTAS----VAMALPALR-ETAASEREELFIQKIQQCCTLFDFS-EPLSDLKFKEVKRAALHEMVDFLTNQNGVITEVIYPEAINMFAVNLFRTLPPSSNPNGAEFDPEEDEPTLESSWPHLQLVYELFLRFLESPDFQPSMAKRFIDHQFVLQLLDLFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNVFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKQFLLKVLLPLHKAKSLSVYHPQLTYCVVQFLEKDPSLSEAVIKSLLKFWPKTHSPKEVMFLNELEELLDVIEPAEFQKVMVPLFRQIAKCVSSPHFQVAERALYYWNNEYIMSLITDNSAVILPIMFPALNRNS--------------------------KTHWNKTIHGLIYNALKLFMEIDQRLFDECSKNYKQEKQMEREKLSQREELWQQVESLAKTNPEWTKARRFNDCLPVSDSRALCDQYSENSDSAYDQSEQRARQPPPPLPPQKQAHQEPREIRGERNKDKPLLRRKSDLPSDSGTVKALNEHKRTDEYLTTPPPDGNY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q61151-1", "uniprot_id": "2A5E_MOUSE", "id": "Q61151-1", "name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSAPTTPPSVDKVDGFSRKSVRKARQ-------------------------------KRSQSSSQFRSQGKP---IELTPLPLLK-DVPTSEQPELFLKKLQQCCVIFDFM-DTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVSCNIFRTLPPSDSN---EFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLYRIS--------------------------KEHWNPAIVALVYNVLKAFMEMNSTMFDELTATYKSDRQREKKKEKEREELWKKLEDLELKR--GLRRD----------GIIPT------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZMG6-1", "uniprot_id": "A0A8I5ZMG6_RAT", "id": "A0A8I5ZMG6-1", "name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSAPTTPPSVDKVDGFSRKSVRKARQ-------------------------------KRSQSSSQFRSQGKP---IELTPLPLLK-DVPTSEQPELFLKKLQQCCVIFDFM-DTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVSCNIFRTLPPSDSN---EFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLYRIS--------------------------KEHWNPAIVALVYNVLKAFMEMNSTMFDELTATYKSDRQREKKKEKEREELWKKLEDLELKR--GLRRD----------GIIPT------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16537-1", "uniprot_id": "2A5E_HUMAN", "id": "Q16537-1", "name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSAPTTPPSVDKVDGFSRKSVRKARQ-------------------------------KRSQSSSQFRSQGKP---IELTPLPLLK-DVPSSEQPELFLKKLQQCCVIFDFM-DTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVSCNIFRTLPPSDSN---EFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLYRIS--------------------------KEHWNPAIVALVYNVLKAFMEMNSTMFDELTATYKSDRQREKKKEKEREELWKKLEDLELKR--GLRRD----------GIIPT------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A6F7R657-1", "uniprot_id": "A0A6F7R657_DROME", "id": "A0A6F7R657-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MISRYRFNTAINITQQQKLIQQLQQQQQQQAIAFREKKQKQKLKLQLQQPLQLQIGQDANGIGGGGEEGVELLGLPKGTENNCKTPNSTAKVANITHKIFGWLRKTRNKRPVEILNSDFGEDGDEGVGE---GKGQGAGEGGGAAASAAGGAADQFPVASVKNKAGKLNTTQTATETAIDSNEPKSEKMSSGTFVDRIDPFAKRSLKKKG--------------------------------KKSQGSSRYRNS-QD---VELQQLPPLKADCSSLEQEELFIRKLRQCCVSFDFM-DPVTDLKGKEIKRAALNDLSTYITHGRGVLTEPVYPEIIRMISCNLFRTLPPSENP---DFDPEEDDPTLEASWPHLQLVYEVFLRFLESQDFQATIGKRVIDQKFVLQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVGELLEILGSIINGFALPLKAEHKQFLVKVLLPLHKVKCLSLYHAQLAYCIVQFLEKDPFLTEPVVRGLLKFWPKTCSQKEVMFLGEIEEILDVIDPPQFVKIQEPLFRQIAKCVSSPHFQVAERALYLWNNEYAMSLIEENNAVIMPIMFPALYRIS--------------------------KEHWNQTIVALVYNVLKTFMEMNSKLFDELTSSYKAERQKEKKRERDREELWKKLHELESNRSSGRTAG----------GSATTSNSAASAASTSLQPPSSAG-------------LNSHQQQSNSGSSGSLSSGGAGGDNNPATTNAKIKQDKADN-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6PD03-1", "uniprot_id": "2A5A_MOUSE", "id": "Q6PD03-1", "name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSPSPPAPVACAAISASEKVDGFTRKSVRKAQRQ------------------------------KRSQGSSQFRSQGSQ---AELHPLPQLK-DATSNEQQELFCQKLQQCCVLFDFM-DSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAYSDIVKMISANIFRTLPPSDNP---DFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKIS--------------------------KEHWNQTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELQLKKALEKQNN----------AYNMHSIRSSTSAK---------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZDI7-1", "uniprot_id": "D3ZDI7_RAT", "id": "D3ZDI7-1", "name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSPSPPAPVACAAISASEKVDGFTRKSVRKAQRQ------------------------------KRSQGSSQFRSQGSQ---AELHPLPQLK-DATSNEQQELFCQKLQQCCVLFDFM-DSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAYSDIVKMISANIFRTLPPSDNP---DFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGMRAFIRKQTNNIFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKIS--------------------------KEHWNQTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQNN----------AYNMHSILSNTSAQ---------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15172-1", "uniprot_id": "2A5A_HUMAN", "id": "Q15172-1", "name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSSSPPAGAASAAISASEKVDGFTRKSVRKAQRQ------------------------------KRSQGSSQFRSQGSQ---AELHPLPQLK-DATSNEQQELFCQKLQQCCILFDFM-DSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAYSDIVKMISANIFRTLPPSDNP---DFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKIS--------------------------KEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQNS----------AYNMHSILSNTSAE---------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B7J5-1", "uniprot_id": "A0A8M2B7J5_DANRE", "id": "A0A8M2B7J5-1", "name": "Serine/threonine protein phosphatase 2A regulatory subunit", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MS-----------AISASEKVDGFTRKSVRKAQRQ------------------------------RVCQGSSQFAVNSSRPAAPEISALPQLK-DASSTEQHELFMQKLQQCCKLFDFY-DTVTDLKSKETKRATLSELVDYVSTNRGVLVEPVYPEITTMVSTNIFRTLPPSENP---DFDPEEDEPTLEASWPHMQLVYEFFLRFLENPDFQPSTAKRYIDQKFVLQLLELFDSEDPREREFLKTILHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKILIPLHTAKPLALFHAQLAYCVVQFLEKDPTLTEVVVRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIQEPLFKQIAKCVASPHFQVAERALYYWNNEYILSLIEENNAKIFPIMFGNLYRIS--------------------------KEHWNPTIVALVYNVLKTMMEMNSKLFDELTTSYKSDRQREKKKEQEREELWRRLDELRMKEVLMIQNN----------RHDIQFTYNNNNHH---------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6PD28-1", "uniprot_id": "2A5B_MOUSE", "id": "Q6PD28-1", "name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METKLPPASTPTSPSSPGLSPVPPPDKVDGFSRRSLRRARP-------------------------------RRSHSSSQFRYQSNQ---QELTPLPLLK-DVPASELHELLSRKLAQCGVMFDFL-DCVADLKGKEVKRAALNELVECVGCTRGVLIEPVYPDIIRMISVNIFRTLPPSENP---EFDPEEDEPNLEPSWPHLQLVYEFFLRFLESPDFQPSVAKRYVDQKFVLMLLELFDSEDPREREYLKTILHRVYGKFLGLRAYIRKQCNHIFLRFIYELEHFNGVAELLEILGSIINGFALPLKTEHKQFLVRVLIPLHSVKSLSVFHAQLAYCVVQFLEKDATLTEHVIRGLLKYWPKTCTQKEVMFLGEMEEILDVIEPSQFVKIQEPLFKQVARCVSSPHFQVAERALYFWNNEYILSLIEDNCHTVLPAVFGTLYQVS--------------------------KEHWNQTIVSLIYNVLKTFMEMNGKLFDELTASYKLEKQQEQQKAQERQELWRGLEELRLRRLQGTQGA----------KEAPVPRPTPQVAASGGQS----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q80W83-1", "uniprot_id": "2A5B_RAT", "id": "Q80W83-1", "name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METKLPPASTPTSPSSPGLSPVPPPDKVDGFSRRSLRRARP-------------------------------RRSHSSSQFRYQSNQ---QELTPLPLLK-DVPASELHELLSRKLAQCGVMFDFL-DCVADLKGKEVKRAALNELVECVGSTRGVLIEPVYPDIIRMISVNIFRTLPPSENP---EFDPEEDEPNLEPSWPHLQLVYEFFLRFLESPDFQPSVAKRYVDQKFVLMLLELFDSEDPREREYLKTILHRVYGKFLGLRAYIRKQCNHIFLRFIYELEHFNGVAELLEILGSIINGFALPLKTEHKQFLVRVLIPLHSVKSLSVFHAQLAYCVVQFLEKDATLTEHVIRGLLKYWPKTCTQKEVMFLGEMEEILDVIEPSQFVKIQEPLFKQVARCVSSPHFQVAERALYFWNNEYILSLIEDNCHTVLPAVFGTLYQVS--------------------------KEHWNQTIVSLIYNVLKTFMEMNGKLFDELTASYKLEKQQEQQKAQERQELWRGLEELRLRRLQGTQGA----------KEAPVPRPTPQVAASGGQS----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15173-1", "uniprot_id": "2A5B_HUMAN", "id": "Q15173-1", "name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METKLPPASTPTSPSSPGLSPVPPPDKVDGFSRRSLRRARP-------------------------------RRSHSSSQFRYQSNQ---QELTPLPLLK-DVPASELHELLSRKLAQCGVMFDFL-DCVADLKGKEVKRAALNELVECVGSTRGVLIEPVYPDIIRMISVNIFRTLPPSENP---EFDPEEDEPNLEPSWPHLQLVYEFFLRFLESPDFQPSVAKRYVDQKFVLMLLELFDSEDPREREYLKTILHRVYGKFLGLRAYIRKQCNHIFLRFIYEFEHFNGVAELLEILGSIINGFALPLKTEHKQFLVRVLIPLHSVKSLSVFHAQLAYCVVQFLEKDATLTEHVIRGLLKYWPKTCTQKEVMFLGEMEEILDVIEPSQFVKIQEPLFKQVARCVSSPHFQVAERALYFWNNEYILSLIEDNCHTVLPAVFGTLYQVS--------------------------KEHWNQTIVSLIYNVLKTFMEMNGKLFDELTASYKLEKQQEQQKAQERQELWQGLEELRLRRLQGTQGA----------KEAPLQRLTPQVAASGGQS----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38903-1", "uniprot_id": "2A5D_YEAST", "id": "P38903-1", "name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MMRGFKQRLIKKTTGSSSSSSSKKKDKEKEKEKSSTTSSTSKKPASASSSSHGTTHSSASSTGSKSTTEKGKQSGSVPSQGKHHSSSTSKTKTATTPSSSSSSSRSSSVSRSGSSSTKKTSSRKGQEQSKQSQQPSQSQKQGSSSSSAAIMNPTPVLTVTKDDKSTSGEDHAHPTLLGAVSAVPSSPISNASGTAVSSDVENGNSNNNNMNINTSNTQDANHASSQSIDIPRSSHSFERLPTPTKLNPDTDLELIKTPQR---------------------------------HSSSRFEPSRYT----PLTKLPNFN-EVSPEERIPLFIAKVDQCNTMFDFN-DPSFDIQGKEIKRSTLDELIEFLVTNRFTYTNEMYAHVVNMFKINLFRPIPPPVNPVGDIYDPDEDEPVNELAWPHMQAVYEFFLRFVESPDFNHQIAKQYIDQDFILKLLELFDSEDIRERDCLKTTLHRIYGKFLSLRSFIRRSMNNIFLQFIYETEKFNGVAELLEILGSIINGFALPLKEEHKVFLVRILIPLHKVRCLSLYHPQLAYCIVQFLEKDPLLTEEVVMGLLRYWPKINSTKEIMFLNEIEDIFEVIEPLEFIKVEVPLFVQLAKCISSPHFQVAEKVLSYWNNEYFLNLCIENAEVILPIIFPALYELTSQLELDTANGEDSISDPYMLVEQAINSGSWNRAIHAMAFKALKIFLETNPVLYENCNALYLSSVKETQQRKVQREENWSKLEEYVKNLRINNDKD----------QYTIKNPELRNSFNTASEN-------------------NTLNEENENDCDSEIQ-----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : * :. : .. : *: *: ** *** : *:: ** **: * :: : . : *.. *. *:**.:**. . :**:**:* * :***:* ***.*:**:*. :*: .*: :*:.*: **:****** ***: *** ***:*****.:*::**:. *::* :*:** *:.**:.****************** *** **:::*:*:*..: *:::*.**:**:******:. *:* *: .*:::*** : **:***.*:*::::**:* :* *: *** *:::*::*.******:.* ***** :.* :* ::* :* * . : . ** :* .: ::.** ::* : :::: . : . : : :*:* * :.. ", "identical_positions": 164, "similar_positions": 135, "identity": "16.09%" }, { "cls_id": "homologset.agr.SGD:S000005542", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BK85-1", "uniprot_id": "TMED1_RAT", "id": "Q5BK85-1", "name": "Transmembrane emp24 domain-containing protein 1", "aln": "--MMAAGAAVALALWLL--LPAVGV-GEAGPPPIQDGEFTFLLPAGRKQCFYQSAPANA-SLETEYQVIGG--AGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYRLCFDNSFSTISEKLVFFELIFDSFQDEEE-VEGWAEAVEPE-----EMLDVKMEDIKESIETMRTRLERSIQMLTLLRAFEARDRNLQEDNLERVNFWSAANVAVLLLVAVLQVCTLKRFFHDKCPVPT-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3V009-1", "uniprot_id": "TMED1_MOUSE", "id": "Q3V009-1", "name": "Transmembrane emp24 domain-containing protein 1", "aln": "--MMAAGAAVALALWLL--LPAVGV-GEAGPPPIQDGEFTFLLPAGRKQCFYQSAPANA-SLETEYQVIGG--AGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYRLCFDNSFSTISEKLVFFELIFDSFQDEEE-VEGWAEAVEPE-----EMLDVKMEDIKESIETMRTRLERSIQMLTLLRAFEARDRNLQEDNLERVNFWSAANVAVLLLVAVLQVCTLKRFFHDKRPVPT-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13445-1", "uniprot_id": "TMED1_HUMAN", "id": "Q13445-1", "name": "Transmembrane emp24 domain-containing protein 1", "aln": "--MMAAGAALALALWLL--MPPVEV-GGAGPPPIQDGEFTFLLPAGRKQCFYQSAPANA-SLETEYQVIGG--AGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYKLCFDNSFSTISEKLVFFELIFDSLQDDEE-VEGWAEAVEPE-----EMLDVKMEDIKESIETMRTRLERSIQMLTLLRAFEARDRNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDKRPVPT-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CXE7-1", "uniprot_id": "TMED5_MOUSE", "id": "Q9CXE7-1", "name": "Transmembrane emp24 domain-containing protein 5", "aln": "---MGGRMWLPFPVLLLSALPAALLRGAAGFTPSLDSDFTFTLPAGRKECFYQPMPLKA-SLEIEYQVLDG--GELDIDFHLTSPEGRTLVFEQRKSDGVHTIE-TEDGDYMFCFDNTFSTISEKVIFFELILDNMGEEVQGQEDWKKYITNT-----DVLEMKLEDILESINSIKSRLSKSGHIQTLLRAFEARDRNIQESNFDRVNFWSVVNLMVMVVVSAIQVYTLKSLFEDKRKSRT-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AXN3-1", "uniprot_id": "TMED5_RAT", "id": "Q6AXN3-1", "name": "Transmembrane emp24 domain-containing protein 5", "aln": "---MGVRMWLPFPMLLLSALPATLLSGAAGFTPSLDSDFTFTLPAGQKECFYQPMPLKA-SLEIEYQVLDG--GELDIDFHLASPEGRTLVFEQRKSDGVHTVE-TEDGDYMFCFDNTFSTISEKVIFFELILDNMGEEVEGQEDWKKYITNT-----DVLEMKLEDILESINSIKSRLSKSGHIQTLLRAFEARDRNIQESNFDRVNFWSVVNLMVMVVVSAIQVYTLKSLFEDKRKSRT-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y3A6-1", "uniprot_id": "TMED5_HUMAN", "id": "Q9Y3A6-1", "name": "Transmembrane emp24 domain-containing protein 5", "aln": "---MGDKIWLPFPVLLLAALPPVLLPGAAGFTPSLDSDFTFTLPAGQKECFYQPMPLKA-SLEIEYQVLDG--AGLDIDFHLASPEGKTLVFEQRKSDGVHTVE-TEVGDYMFCFDNTFSTISEKVIFFELILDNMGEQAQEQEDWKKYITGT-----DILDMKLEDILESINSIKSRLSKSGHIQTLLRAFEARDRNIQESNFDRVNFWSMVNLVVMVVVSAIQVYMLKSLFEDKRKSRT-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXY9-1", "uniprot_id": "Q9VXY9_DROME", "id": "Q9VXY9-1", "name": "", "aln": "----MQAIWLGMPGLVLLLSIAALLLGVQD-AEAYDKEMTVYVDAGKTECLYHSVRQGE-TIDFEYQVIDGGHGDLDISFTLLDPIGLVIVSDFKKPENVHRHEVAKEGDYRFCFDNSFSMFNRKTVFFELIVEREGEELQGDTQWNEADELTGLSRDEYYDMKVQDIMDFIGRIRLQLTKARQLQDVLRSHEARDRNLAESNFQKVNHWSMVQISAMIGVGLIQVFMLRSIFATGGRMHNLWRKLGI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D3YZZ5-1", "uniprot_id": "D3YZZ5_MOUSE", "id": "D3YZZ5-1", "name": "Transmembrane emp24 domain-containing protein 7", "aln": "MPRPGSAPRWAAAAGRWGCRLLA--LLLLLPAPSGGSEITFELPDNAKQCFYEDITQGT-KCTLEFQVITG--GHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASRNGTYKFCFSNEFSTFTHKTVYFDFQVGEDPPLFPSE-NRVSALT---------------QMESACVSIHEALKSVIDYQTHFRLREAQGRSRAEDLNTRVAYWSVGEALILLVVSVGQVFLLKSFFSDKRTTTTRVGS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3B3-1", "uniprot_id": "TMED7_HUMAN", "id": "Q9Y3B3-1", "name": "Transmembrane emp24 domain-containing protein 7", "aln": "MPRPGSAQRWAAVAGRWGCRLLA--LLLLVPGPGGASEITFELPDNAKQCFYEDIAQGT-KCTLEFQVITG--GHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHKTVYFDFQVGEDPPLFPSE-NRVSALT---------------QMESACVSIHEALKSVIDYQTHFRLREAQGRSRAEDLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTTRVGS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZTX0-1", "uniprot_id": "TMED7_RAT", "id": "D3ZTX0-1", "name": "Transmembrane emp24 domain-containing protein 7", "aln": "MPRPRSATCWAAAAGRWSCRLLALLLLLLLPGPSGGSEITFELPDNAKQCFYEDITQGT-KCTLEFQVITG--GHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHKTVYFDFQVGEDPPLFPSE-NRVSALT---------------QMESACVSIHEALKSVIDYQTHFRLREAQGRSRAEDLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTTRVGS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1RAM9-1", "uniprot_id": "F1RAM9_DANRE", "id": "F1RAM9-1", "name": "Transmembrane emp24 domain-containing protein 7", "aln": "---------MAGSSSSWLLPLFVQ-VVMMKVGLSSASELTFELPDNAKQCFYEDITIGT-KCTLEFQVVTG--GHYDVDCRLEDPEGTVLYKEMKKQYDSFTFSAARNGTYKFCFSNEFSTFTHKTVYFDFQVGDDPPLFPNE-NRVTALT---------------QMESACVSIHEALKSVMDYQTHFRLREAQGRSRAEDLNSRVAFWSVGEALILLVVSVSQVLLLRSFFSDRKTTTTRMGS---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q78IS1-1", "uniprot_id": "TMED3_MOUSE", "id": "Q78IS1-1", "name": "Transmembrane emp24 domain-containing protein 3", "aln": "------MVHEAPHASSFQMLLQLLLLLLLRAEPLRSAELTFELPDNAKQCFHEEVEQGV-KFSLDYQVITG--GHYDVDCYVEDPRGNVIYRETKKQYDSFTYKTEAKGVYRFCFSNEFSTFSHKTVYFDFQVGDEPPILPDMGNRVTALT---------------QMESACVTIHEALKTVIDSQTHYRLREAQDRARAEDLNSRVSYWSVGETIALFVVSFSQVLLLKSFFTEKRPVNRAVHS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AY25-1", "uniprot_id": "TMED3_RAT", "id": "Q6AY25-1", "name": "Transmembrane emp24 domain-containing protein 3", "aln": "------MGNEVPRASSFQMLMLLLLLLLLRAERLRGAELTFELPDNAKQCFHEEVEQGV-KFSLDYQVITG--GHYDVDCYVEDPMGNIIYRETKKQYDSFTYKTEVKGVYRFCFSNEFSTFSHKTVYFDFQVGDEPPILPDMGNRVTALT---------------QMESACVTIHEALKTVIDSQTHYRLREAQDRARAEDLNSRVSYWSVGETIALFVVSFSQVLLLKSFFTEKRPINRAVHS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y3Q3-1", "uniprot_id": "TMED3_HUMAN", "id": "Q9Y3Q3-1", "name": "Transmembrane emp24 domain-containing protein 3", "aln": "------MGSTVPRSAS----VLLLLLLLRRAEQPCGAELTFELPDNAKQCFHEEVEQGV-KFSLDYQVITG--GHYDVDCYVEDPQGNTIYRETKKQYDSFTYRAEVKGVYQFCFSNEFSTFSHKTVYFDFQVGDEPPILPDMGNRVTALT---------------QMESACVTIHEALKTVIDSQTHYRLREAQDRARAEDLNSRVSYWSVGETIALFVVSFSQVLLLKSFFTEKRPISRAVHS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12450-1", "uniprot_id": "ERP4_YEAST", "id": "Q12450-1", "name": "Protein ERP4", "aln": "-----------MRVFTLIAILFSSSLLTHAFSSNYAP-VGISLPAFTKECLYYDLSSDKDVLVVSYQVLTG--GNFEIDFDITAPDGSVIVTERQKKHSDFLLKSFGIGKYTFCLSNNYGTSPKK---VEITLEKEKEIVSSHESKEDIIAN-----------------NAIEEIDRNLNKITKTMDYLRAREWRNMYTVSSTESRLTWLSLLIMGVMVGISIVQALIIQFFFTSRQKNYV-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : .:*:: .:**: * . ::. : * * : : :* . . * * :*:.* :. .* .:: . . : * . * * :. .. :: * :. :. *. :: :* ", "identical_positions": 18, "similar_positions": 47, "identity": "7.26%" }, { "cls_id": "homologset.agr.SGD:S000005544", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZPW1-1", "uniprot_id": "D3ZPW1_RAT", "id": "D3ZPW1-1", "name": "Arrestin domain-containing protein 2", "aln": "-----------MLFDKVKAFVVELDGTRAGTEPVFHGGQAVAGRVLLELAGAARVGALRLRARGRARAHWTESRSA-------------------------------------------GSST-AYTQSYSERVEVVNHRATLLAPDSGD---------IVMLPAGRHEFPFSFQLPIS-LVTSFEGKHGSVRYSIKATLHRP-WVPARRARKVFTVIEPVDIN-TPALL-EPQAGAREKVARSWYCT----------------------------------------------------------RGLVSLSAKIDR---------------------------------------------KGYTPGEVIPIFAEIDNGSTRAVQPRAALVQTQTFMARGARKQK------CAVVASVDGEPVGPGRRALWPGR------------ALRIPPVG-PSILHCRVLSVDYSLKVCVDIPGSS---KLLLELPLVIGTVPLHPLGSRSASVGSRASFLQDWGL--------------------------------------------------------------------------------CALMERPEAPPEYSEVVRESPQVAASQGLFSFLHDPDVTTE-----------------------------------------GPYFACLQEFRYRPPPLYS----------------EEDPNP-PSEAARPRCMTC------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D668-1", "uniprot_id": "ARRD2_MOUSE", "id": "Q9D668-1", "name": "Arrestin domain-containing protein 2", "aln": "-----------MLFDKVKAFVVEIDGARTGTEPVFHGGQAVAGRVLLELAGAARVGALRLRARGRARAHWTESRSA-------------------------------------------GSST-AYTQSYSERVEVVNHRATLLAPDSGD---------IATLPAGRHEFPFSFQLPIS-LVTSFEGKHGSVRYSIKATLHRP-WVPARCARKVFTVIEPVDIN-TPALL-EPQAGAREKVARSWYCT----------------------------------------------------------RGLVSLSAKIDR---------------------------------------------KGYTPGEVIPIFAEIDNGSTRAVQPRAALVQTQTFMARGARKQK------RAVVASVDGEPVGPNRRALWPGR------------ALRIPPVG-PSILQCRVLSVDYSLKVFVDIPGSS---KLLLELPLVIGTVPLHPLGSRSASVGSRASFLQDWGL--------------------------------------------------------------------------------CTMMDRPEAPPEYSEVVRESQLVCASPGPSSLLHDLGVTTE-----------------------------------------GPYFACLQEFRYCPPPLYS----------------EEDPNP-PSEAVRPRCMTC------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TBH0-1", "uniprot_id": "ARRD2_HUMAN", "id": "Q8TBH0-1", "name": "Arrestin domain-containing protein 2", "aln": "-----------MLFDKVKAFSVQLDGATAGVEPVFSGGQAVAGRVLLELSSAARVGALRLRARGRAHVHWTESRSA-------------------------------------------GSST-AYTQSYSERVEVVSHRATLLAPDTGE---------TTTLPPGRHEFLFSFQLPPT-LVTSFEGKHGSVRYCIKATLHRP-WVPARRARKVFTVIEPVDIN-TPALL-APQAGAREKVARSWYCN----------------------------------------------------------RGLVSLSAKIDR---------------------------------------------KGYTPGEVIPVFAEIDNGSTRPVLPRAAVVQTQTFMARGARKQK------RAVVASLAGEPVGPGQRALWQGR------------ALRIPPVG-PSILHCRVLHVDYALKVCVDIPGTS---KLLLELPLVIGTIPLHPFGSRSSSVGSHASFLLDWRL--------------------------------------------------------------------------------GALPERPEAPPEYSEVVADTEEAALGQSPFPLPQDPDMSLE-----------------------------------------GPFFAYIQEFRYRPPPLYS----------------EEDPNP-LLGDMRPRCMTC------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TPQ9-1", "uniprot_id": "ARRD3_MOUSE", "id": "Q7TPQ9-1", "name": "Arrestin domain-containing protein 3", "aln": "-----------MVLGKVKSLTISFDCLNDSNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNA-------------------------------------------GSNT-AYTQNYTEEVEYFNHKDILIGHERDDDNSEE---GFHTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRP-WLLPVKLKKEFTVFEHIDIN-TPSLL-SPQAGTKEKTLCCWFCT----------------------------------------------------------SGPISLSAKIER---------------------------------------------KGYTPGESIQIFAEIENCSSRMVVPKAAIYQTQAFYAKGKMKEV------KQLVANLRGESLSSGKTETWNGK------------LLKIPPVS-PSILDCSIIRVEYSLMVYVDIPGAM---DLLLSLPLVIGTIPLHPFGSRTSSVSSQCSMSMNWLA--------------------------------------------------------------------------------LALPERPEAPPSYAEVVTE-EQRRNNLAPVGACDDFERALQ-----------------------------------------GPLFAYIQEFRFLPPPLYS----------------EIDPNPDQSSEDRPSCPSR------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6TXF1-1", "uniprot_id": "ARRD3_RAT", "id": "Q6TXF1-1", "name": "Arrestin domain-containing protein 3", "aln": "-----------MVLGKVKSLTISFDCLNDSNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNA-------------------------------------------GSNT-AYTQNYTEEVEYFNHKDILIGHERDDDNCEE---GFSTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRP-WLLPVKLKKEFTVFEHIDIN-TPSLL-SPQAGTKEKTLCCWFCT----------------------------------------------------------SGPISLSAKIER---------------------------------------------KGYTPGESIQIFAEIENCSSRMVVPKAAIYQTQAFYAKGKMKEV------KQLVANLRGESLSSGKTETWDGK------------LLKIPPVS-PSILDCSIIRVEYSLMVYVDIPGAM---DLLLSLPLVIGTIPLHPFGSRTSSVSSQCSMNMNWLG--------------------------------------------------------------------------------LSLPERPEAPPSYAEVVTE-EQRRNNLAPVSACDDFERALQ-----------------------------------------GPLFAYIQEFRFLPPPLYS----------------EIDPNPDQSSEDRPSCPSR------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96B67-1", "uniprot_id": "ARRD3_HUMAN", "id": "Q96B67-1", "name": "Arrestin domain-containing protein 3", "aln": "-----------MVLGKVKSLTISFDCLNDSNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNA-------------------------------------------GSNT-AYTQNYTEEVEYFNHKDILIGHERDDDNSEE---GFHTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRP-WLLPVKLKKEFTVFEHIDIN-TPSLL-SPQAGTKEKTLCCWFCT----------------------------------------------------------SGPISLSAKIER---------------------------------------------KGYTPGESIQIFAEIENCSSRMVVPKAAIYQTQAFYAKGKMKEV------KQLVANLRGESLSSGKTETWNGK------------LLKIPPVS-PSILDCSIIRVEYSLMVYVDIPGAM---DLFLNLPLVIGTIPLHPFGSRTSSVSSQCSMNMNWLS--------------------------------------------------------------------------------LSLPERPEAPPSYAEVVTE-EQRRNNLAPVSACDDFERALQ-----------------------------------------GPLFAYIQEFRFLPPPLYS----------------EIDPNPDQSADDRPSCPSR------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J1F4-1", "uniprot_id": "ARRD4_MOUSE", "id": "A0A0B4J1F4-1", "name": "Arrestin domain-containing protein 4", "aln": "MGGEAG---ADGPRGRVKSLGLVFEDESKG---CYSSGETVAGHVLLEAAEPVALRGLRLEAQGRATSAWGPSAGA-------------------------------------------RVCIGGGSPAASSEVEYLNLRLSLLEAPAGEG--------VTLLQPGKHEFPFRFQLPSEPLATSFTGKYGSIQYCVRAVLERP-QVPDQSVRRELQVVSHVDVN-TPPLL-TPMLKTQEKMVGCWLFT----------------------------------------------------------SGPVSLSVKIER---------------------------------------------KGYCNGEAIPIYAEIENCSSRLVVPKAAIFQTQTYLASGKTKTV------RHMVANVRGNHIGSGSTDTWNGK------------MLKIPPVT-PSILDCCIIRVDYSLAVYIHIPGAK---RLMLELPLVIGTIPYSGFGRRNSSVASQFSMDMCWLA--------------------------------------------------------------------------------LALPEQPEAPPNYADVVSE-EEFSRHVPPYPQPSDCDGEAC-----------------------------------------YSMFACIQEFRFQPPPLYS----------------EVDPHPGDAQETQPVSFIL------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCT1-1", "uniprot_id": "ARRD4_HUMAN", "id": "Q8NCT1-1", "name": "Arrestin domain-containing protein 4", "aln": "MGGEAGCAAAVGAEGRVKSLGLVFEDERKG---CYSSGETVAGHVLLEASEPVALRALRLEAQGRATAAWGPSTCP-------------------------------------------RASASTAALAVFSEVEYLNVRLSLREPPAGEG--------IILLQPGKHEFPFRFQLPSEPLVTSFTGKYGSIQYCVRAVLERP-KVPDQSVKRELQVVSHVDVN-TPALL-TPVLKTQEKMVGCWFFT----------------------------------------------------------SGPVSLSAKIER---------------------------------------------KGYCNGEAIPIYAEIENCSSRLIVPKAAIFQTQTYLASGKTKTI------RHMVANVRGNHIASGSTDTWNGK------------TLKIPPVT-PSILDCCIIRVDYSLAVYIHIPGAK---KLMLELPLVIGTIPYNGFGSRNSSIASQFSMDMSWLT--------------------------------------------------------------------------------LTLPEQPEAPPNYADVVSE-EEFSRHIPPYPQPPNCEGEVC-----------------------------------------CPVFACIQEFRFQPPPLYS----------------EVDPHPSDVEESQPVSFIL------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BG60-1", "uniprot_id": "TXNIP_MOUSE", "id": "Q8BG60-1", "name": "Thioredoxin-interacting protein", "aln": "----------MVMFKKIKSFEVVFND----PEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQG-----------------------------------------------------SQQCKQTLDYLRYEDTLLLEEQPTAGENE---MVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGCVDYWVKAFLDRP-SQPTQEAKKNFEVMDLVDVN-TPDLM-APVSAKKEKKVSCMFIP----------------------------------------------------------DGRVSVSARIDR---------------------------------------------KGFCEGDDISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVF------TQKLSSVRGNHIISGTCASWRGK------------SLRVQKIR-PSILGCNILKVEYSLLIYVSVPGSK---KVILDLPLVIGSR--SGLSSRTSSMASRTSSEMSWID--------------------------------------------------------------------------------LNIPDTPEAPPCYMDIIPEDHRLESPTTP--LLDDVDDSQD-----------------------------------------SPIFMYAPEFQFMPPPTYT----------------EVDPCVLNNNNNNNNVQ--------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M7W1-1", "uniprot_id": "TXNIP_RAT", "id": "Q5M7W1-1", "name": "Thioredoxin-interacting protein", "aln": "----------MVMFKKIKSFEVVFND----PEKVYGSGEKVAGRVTVEVCEVTRVKAVRILACGVAKVLWMQG-----------------------------------------------------SQQCKQTLDYLRYEDTLLLEDQPT-GENE---MVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGCVDYWVKAFLDRP-SQPTQEAKKNFEVMDLVDVN-TPDLM-APVSAKKEKKVSCMFIP----------------------------------------------------------DGRVSVSARIDR---------------------------------------------KGFCEGDDISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVL------TQKLSSVRGNHIISGTCASWRGK------------SLRVQKIR-PSILGCNILRVEYSLLIYVSVPGSK---KVILDLPLVIGSR--SGLSSRTSSMASRTSSEMSWID--------------------------------------------------------------------------------LNIPDTPEAPPCYMDVIPEDHRLESPTTP--LLDDVDDSQD-----------------------------------------SPIFMYAPEFQFMPPPTYT----------------EVDPCVLNNNNNN--VQ--------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H3M7-1", "uniprot_id": "TXNIP_HUMAN", "id": "Q9H3M7-1", "name": "Thioredoxin-interacting protein", "aln": "----------MVMFKKIKSFEVVFND----PEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQG-----------------------------------------------------SQQCKQTSEYLRYEDTLLLEDQPT-GENE---MVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGCVDYWVKAFLDRP-SQPTQETKKNFEVVDLVDVN-TPDLM-APVSAKKEKKVSCMFIP----------------------------------------------------------DGRVSVSARIDR---------------------------------------------KGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVL------TQKLSSVRGNHIISGTCASWRGK------------SLRVQKIR-PSILGCNILRVEYSLLIYVSVPGSK---KVILDLPLVIGSR--SGLSSRTSSMASRTSSEMSWVD--------------------------------------------------------------------------------LNIPDTPEAPPCYMDVIPEDHRLESPTTP--LLDDMDGSQD-----------------------------------------SPIFMYAPEFKFMPPPTYT----------------EVDPCILNNNVQ-------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99KN1-1", "uniprot_id": "ARRD1_MOUSE", "id": "Q99KN1-1", "name": "Arrestin domain-containing protein 1", "aln": "-------------MGRVQLFEIRLSQ----GRVVYGPGEPLAGTVHLRLGAPLPFRAIRVTCMGSCGVSTKAN-----------------------------------------------------DGAWVVEESYFNSSLSLADK--------------GSLPAGEHNFPFQFLLPAT-APTSFEGPFGKIVHQVRASIDTPRFSKDHKCSLVFYILSPLNLNSIPDIE-QPNVASTTKKFSYKLVK----------------------------------------------------------TGNVVLTASTDL---------------------------------------------RGYVVGQVLRLQADIENQSGKDTSPVVASLLQKVSYKAKRWIYD------VRTIAEVEGTGVKAWRRAQWQEQ------------ILVPALPQ-SALPGCSLIHIDYYLQVSMKAP------EATVTLPLFVGNIAVNQTPLSPCP---GRESSPG-----------------------------------------------------------------------------------TLSLVVPSAPPQE--EAEAVASGPHFSDPVSLSTKSHSQQQPLSAPLGSVSVT----TTEPWVQVGSPARHSLHP-PLCISIGATVPYFAEGSAGPVPTTS----------------ALILPPEYSSWGYPYEAPPSYEQSCGAAGTDLGLIPGS-----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0BNL6-1", "uniprot_id": "ARRD1_RAT", "id": "B0BNL6-1", "name": "Arrestin domain-containing protein 1", "aln": "-------------MGRVQLFEIRLSQ----GRVVYSPGEPLAGAVHLRLGAPLPFRAIRVTCMGSCGVSNKAN-----------------------------------------------------DGAWVVEESYFNSSLSLADK--------------GSLPPGEHNFPFQFLLPAT-APTSFEGPFGKIVHQVRASIDTPRFSKDHKCSLVFYILSPLNLNSIPDIE-QPNVASTTKKFSYKLVK----------------------------------------------------------TGSVVLTASTDL---------------------------------------------RGYVVGQVLRLQADIENQSGKDTSPVVASLLQKVSYKAKRWIYD------VRTIAEVEGTGVKAWRHAQWQEQ------------ILVPALPQ-SALPGCSLIHIDYYLQVSMKAP------EATVTLPLFVGNIAVNQTPLSPCP---GPGSSPG-----------------------------------------------------------------------------------LLSPVVPSAPPQE--EAEAVASGPHFSDPVSLSTKSHSQQQPLSTTLGSVSVT----TIEPCVQVGSPARHSLHP-PLCISIGATVPYFAEGSGGPVPTTS----------------ALILPPEYSSWGYPYEAPPSYEQSCGAGGTDVGLIPGS-----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N5I2-1", "uniprot_id": "ARRD1_HUMAN", "id": "Q8N5I2-1", "name": "Arrestin domain-containing protein 1", "aln": "-------------MGRVQLFEISLSH----GRVVYSPGEPLAGTVRVRLGAPLPFRAIRVTCIGSCGVSNKAN-----------------------------------------------------DTAWVVEEGYFNSSLSLADK--------------GSLPAGEHSFPFQFLLPAT-APTSFEGPFGKIVHQVRAAIHTPRFSKDHKCSLVFYILSPLNLNSIPDIE-QPNVASATKKFSYKLVK----------------------------------------------------------TGSVVLTASTDL---------------------------------------------RGYVVGQALQLHADVENQSGKDTSPVVASLLQKVSYKAKRWIHD------VRTIAEVEGAGVKAWRRAQWHEQ------------ILVPALPQ-SALPGCSLIHIDYYLQVSLKAP------EATVTLPVFIGNIAVNHAPVSPRP---GLGLPPG-----------------------------------------------------------------------------------APPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLATLSSVPG-----APEPCPQDGSPASHPLHP-PLCISTGATVPYFAEGSGGPVPTTS----------------TLILPPEYSSWGYPYEAPPSYEQSCG--GVEPSLTPES-----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A7Q5-1", "uniprot_id": "A0AB13A7Q5_DANRE", "id": "A0AB13A7Q5-1", "name": "", "aln": "-------------MGKVQEFEITFTN----NKVVYNPGESISGTVRIKSSHSLQFKAIKVCCVGSCGISSKLN-----------------------------------------------------DASWMLEEKYLSSTLSVADK--------------GTLPPGEHSFPFQFLIPAS-VPTSFEGPFGKILYKIRAFIDTPRFSKDYKAQRPFYLLNVLNLNELPDIE-QPSCAVTTKKFNYLLVK----------------------------------------------------------TGTLMLKAYTDL---------------------------------------------RGYTPGQVIKLSAEIHNKSGKDTGYVMASLIQRVSYKTKRPVFD------LRPIAEVEGAGVKAGKHAEWREQ------------IIVPPLPQ-SGLTGCNLIDIEYFIQVSLKSP------EAAVTLPIYIGNIAVNLTPSIPHPMAHGVPMPTGPSL--------------------------------------------------------------------------------NPAAVVPSAPPVEEELAGQLAAGG--GDSEEIPTKSHSQQDPSGAPLSVAPYGHASGPVLPQSQQHVQSTDGSAP-LFCLSTGATIPFFTDGNATPVPTSC----------------PLILPPEYSTWEYPHEPPPTYEESCSSNNSSFNSSMR------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TT80-1", "uniprot_id": "A0AB32TT80_DANRE", "id": "A0AB32TT80-1", "name": "", "aln": "-------------MGKLQEFEISFDN----NKTVYSPGESLTGTLKISIAQSIQCKAIKVNCQGFCGVTSKSN-----------------------------------------------------DTDWTDEEQYFSSSVSIADK--------------GTLKEGEHSFPFKFLLPAA-APTSFVGPYGQIMYRVRAFIDTPRFAKDYKIEKPFSMTNTLNLNEVPGIR-EPSSSSVTKNFSYMLVK----------------------------------------------------------NGTVVLNAKTDM---------------------------------------------RGYIAGQIIKVSAGIENKSDKTTGHVVASLMQKVTYNTKKQTYD------LRSVAEVEGPGVKGGNKSEWNQQ------------IIVPALPH-SSLSDGNLIQICYYIQVYLKYP------EVALTLPICIGSVALDPSQPSHSQT--VAPMPAPR----------------------------------------------------------------------------------ITPAPSPSAPESEASNLPPRPAPKPAPKPRPRSTHASPSAPPVDLYPQLPSVSNYNGEMLKSPHQEPGSQGPVSPNAFSYAPGLSFRQRQSSSGPSAPPLS----------------LSSSSQDRNQMPSSASVPPSYRSSAYPQATNSEVLDESSSKNW------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7K8-1", "uniprot_id": "Q9I7K8_DROME", "id": "Q9I7K8-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "----------------MVICEIEFCNN---SQGIFYAGQLISGQVVIKTEKEKSVKAVILNIKGYAETHWADTEHD--------------------------------------------PDDQSNGESFNGHVDYLATRAYLHGS------SSS---IEVLIEPGTSSYRFACQLPIT-CPSSFEGTLGRIRYLVNVRFVRP-WKFDLNFNRCFTVIKVMDLNSESLMLRVPSQVESQRTFCCFPCR----------------------------------------------------------SSPLSMRLSVPQ---------------------------------------------SGFVPGQIVPVEVMVSNDS-GVAVEDITVKLTMVVIYYSQPPSA-DTNKDRFEMVLKTGGGVSTKCRQQFTFD------------LKVPPTPP-TCFNLCSIIQIGYQVEAEARVKGCHG--GQSLHMPITIGSVPLT-KQLQKE--PRTWGEVLPPQQL-----------------------------------------------------------------------------DAKALILIGSEQNGEALGSPNPWAADPSIAPPSYAEAKHISPDPHKFSKSKKKSQKRG------------VKGSQERKAETIVFSPLYAVFDLSNQVDEMT-------------------LRANEPKTDG-----GYVNEGVEKSTWL--------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JQV1-1", "uniprot_id": "A8JQV1_DROME", "id": "A8JQV1-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------MGIICQILFHNN---TQGVFYAGQMVAGQVTLSTDKAIQIKAIRLKLKGYAETHWTESKTD--------------------------------------------SNNKSTSESYNGFEKYLSSKVYLLGS------EIS---PEMALEPGTRSYNFACPIPIN-CPSSFEGTHGRIRYMVDVNIIQP-WKYDSIFSRAFTVIQVMDINTYNSVSQVPVQAKTEKTFGVWPFR----------------------------------------------------------SDPLTLELNLPQ---------------------------------------------TGFVPGQTVPANVLIGNES-KIRVHEVKVGLSMMITYYSDLSSG-SKCERKSVAKLKADG-VLRNSRKMYDFQ------------LMIPSTPP-SCFHLCRIIKIGYQIEVVAKVKGMHI--NGTLIMPVTICGVPISPSAVQYT--PQSSGPEAPEQ---------------------------------------------------------------------------------RALTLIEGEGAFAPAAPPYPWSEGSTLSPPNYAEAMHSHSDSEKQSESGNAQEKS--------------------------YKPLYPVFDLSTSTVEKS-------------------KEAALDKEE-------------KK------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7L0-1", "uniprot_id": "Q9I7L0_DROME", "id": "Q9I7L0-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------MTVTCEIDFDNN---PHGTYFGGEVLTGRVTLKLDKMKLVKAITLNITGYAETRWIERVT---------------------------------------------TNRRRRRRTFCGREDYIASKTFLVGS------NLS---SQVSIEAGIHTYNFVCLIPTE-CPSSFEGSHGRVRYMATVTLVRP-WKFDQSYTRCFTVLKVMDLNFDSPLLRVPAHSETSKTYCCWPCR----------------------------------------------------------SDPLALQLTVPQ---------------------------------------------TGFVPGQNVPLSVLVTNDS-HIPVEQLLISFVMLVTYHSKPPSMPNTTSERLVVNTFKGDAVQRNCKKLFSYE------------IRVPATPP-TCFNLCGIIQIAYQVEVEARVKGCHN--NEVVTIPLTIGSVPLA-QHVPIQ--PRGFVPQLNVN-------------------------------------------------------------------------------------ELAVEEVATAPNSSSPWSVDASIPPPNYQEAVHMRSTAATRSDDLDDPEPVP------------PN---TLSLDGGAYKPLYPVFDIPSPSAPPP-------------------TDYTQNYMAERAFVNPAMDVDKDKGTWL--------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7L1-1", "uniprot_id": "Q9I7L1_DROME", "id": "Q9I7L1-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------MVVTCEISFDNN---KHGTFYAGQLVKGCATLKCDRSKEVQAVLLKVVGYSITKWSEKSLG--------------------------------------------STKL-----YVGREDYLSSNTYLVGSEQNNTHNNT---HRLTIEAGVHSYNFTCQLPYQ-CPSSFEGRHGCIRYIVKVLLIRP-WKFDQAYTKGFTVLKMLDLNFDTPQLKSAAHSEGYRTFCCGPCK----------------------------------------------------------TDPLKLELHLPQ---------------------------------------------AGYVPGQKIPVTIVVVNNT-AVAVSEIRLSLVMLVRYYSVSPEH--SRVERLIISRAKGESVLKQCTRSQTID------------LPVPSTPP-TCVELSNLIQIAYQLEVEALVKSLRE--QQLMVMPVTVGTIPLAVSGIVVQQPPRRSAHYEGPDS------------------------------------------------------------------------------RRNPPDELPMVTALESLPSDLASSAADSALP-NYEESRHTQRGNINEEELHAFGSNE--------------------------FAPLYPVYSIPSPTPVLT-------------------ANARNAGFVN---------QSFVK------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VI00-1", "uniprot_id": "Q9VI00_DROME", "id": "Q9VI00-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------MPSSCSFELDR----REPIYYSGETVNGRAILTTTSEKSVNEVYILFEGEAKVRWDERRTRTR-----------------------------------------GGKTEHYTEYFRGKQQYLYTRTSVFGS--------------GNLPPGTHTYNFCIPLPLE-CPSSVVAQYGKIFYEVSVVIDRQ-WRFNNVFKQPLTVIQTYNLN-MSPQLLMPLVREDIKHFCCWPCS----------------------------------------------------------SGPVLSTLTIPF---------------------------------------------GGYAPGQKIRFTLEIDNQSSGYDLNGIELKLKQIYKFQAQTPHHKTREKEHSLNKSCQQERVLRLSKKKIEGT------------LAIPAVPPSSRTEG--IISVSYQVILTISTGDCHV--DSDFEVPIVIGTIPLIQS------------------------------------------------------------------------------------------------------AENPASAAQWIPETPDTPAGAAADLPPSYDKCKPPTFEEATNFGERFIDIDQ------------------DEHNRTDDFIPRYPMYTNFAMPSAPP------------QPPEEFATNQPVPVLSLPHDPTAPLVGQNNTDRPTQSYGWNTNS-----------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VHZ9-1", "uniprot_id": "Q9VHZ9_DROME", "id": "Q9VHZ9-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------MPTTCVFQLDR----LNPVYNSGEYISGRILLRTDKVKRVNAVYVTLEGEAKVQWSMS-----------------------------------------------GKSE--TANYSGHQQYLHSRTNVFDN--------------TLFRAGVHVYVLTLRIPPD-CPSTCKGPYGYIAYTISLTIDKP-WGFDEVFRKPIIVVQTLDLN-YNAEFSLPVKDENLKYLCHWPCI----------------------------------------------------------SGPICSTLTLPA---------------------------------------------SGFTPLQEVPYRLEVDNQSPHYDIIGVEVSIKQHFVFLSRKPVKRN-FYSKTLVKELISDRTLRLSKRQYESS------------ICVPMDTPRSTLNPNYIVFLHYTLQVKLKTGYFHY--DTDLSVPIIVGTTSLQHLRDSVHTQQPVRRTPTPERQRLIERV------------------------------------------------------------------------TPRPPTVEEDSAGEADPATDEPHRVIEDDEPPSYDSCLPPSFSFATLAGSQQTLGSN------------------AAVVLQRIHLPKFPGFSTLIGTAPAHGMEDSGLDMHMYRSYGSLNTDHTGRSLDTFGSLCGPLSEHVEEQEQEAEENLDVTAQVHRPIQRATVSEVENVLQDEHLF-----------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VI53-1", "uniprot_id": "Q9VI53_DROME", "id": "Q9VI53-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "--------------MGLKGCELQLDN----PWNTYYAGQTVNGQVKFTFDSPKKVRGIIIRFLGEANTEWSEEKSVTTS----------------------------------------EGKTENEVTQLKGHEEYFKIQYYLLGGKNSS---------ETELPPGTHTYPFTCALPPN-LPSSFEGEFGHVRYTIKVTLDRP-WKFDQDMKMAFTVIAPVDLN-LNPRVKEPFKLELEKSFCCFCCR----------------------------------------------------------SGPLAVITNIPQ---------------------------------------------TGFVSGQVLPITCEVDNTS-NVNLTAVKFELRKLVTFHTNQPRS-EKRESKVIIANLSVGPVNGGESRTFTQQ------------MEIPALPP-TNLLNCGIIALDYDLHVECEVSGPHR--NLTGKVPITLGTIPLAGVRPPTQFTDAPSAVQSEDPS---------------------------------------------------------------------------------LAPTQPVSPASPPGGDGVGGALGWNVADSTGGGSLYPNIP-----------------------------------------PPQFVETQYRAPTIAGRDD----------------SEHTQMIGDGAFAPRYPTFQFNNATAPPASQ------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KGD9-1", "uniprot_id": "A0A0B4KGD9_DROME", "id": "A0A0B4KGD9-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------MPIECLISFDNN---PQGVYYAGQELSGVVDLSVDATKRIKGIHVTVSGYAKIRWIKKGYP----------------------------------------------RDSERAMCRAYRSYLSSRSYVLGSCANN--------SSIDWPAGEYSYTFHVILPDN-LPTSFDGKYGQIHYEIITTIERA-ARHPKVFKLPFTVIQPLDLN-ADAIYRVPLEILDRKRFWSFCCP----------------------------------------------------------TGPLTVKFSTPY---------------------------------------------CGYAPGQKIHFVLYINNES-SIDIIECEVKLKQEVSYESHDPQHEYR-YDKHLIARKQFGNVLRWSRKVYRGY------------LDLPSIPP-TSVKPTCPISVNYSIKIIVNPTEFHW--KLKLKIPLTIGSIPIMDGPEALLRFNRQQQQHQVVSQNLQMSTQQRQRDRDRDRDMNVDRERDRDRDRDRISASVQQRR-ISSINNNNNNHGRLVGGLLPTNSNMNMITNVSPTPTSSTPSSTPTTAALRPTAMPAILVTSDSDNPPDYIPMMPPSYEDAMALSEKFSDDTEFLTN----VSMSSILSAQADVTTSEPFKPRYPVYYDYETPTIPPET----------------LYDESSSRLRLTLSCQDSAAPETDEDLAPNTRGGEPPSCEKK-------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E8K8-1", "uniprot_id": "Q0E8K8_DROME", "id": "Q0E8K8-1", "name": "", "aln": "------------MPRKLLKFLIIFDN----TSLLYFPGQFLSGRVLIELQDETPALGLHFHVVGEGVVRNGRR-----------------------------------------------------QERTYDKENYIDFRMRLLGDVDQG--------GPAILSPGIHSFPFKLGLPLG-LPSTFLGRYGWIQFYCKAALREN-NGIIHKNHQVFIVMNPIDLNLEKPILAQPFTCEVEHKLGVVCVG----------------------------------------------------------GGQIKCRVSLDR---------------------------------------------GGYVPGENILVTAFISNYS-NVSIKRTKASLTETIEYLARGKVVQTE---KRELAVLVRGKIRPGAKDEWHNE------------LYVPPLPP-TNLHGCHLIKISYDVFFVIEPKSMEK--EIKLQLPIVLATYPFRHSGDAVN-------------------------------------------------------------------------------------------------ANTWPESVLKPDTHTHYPSTLPIFRPWLHEKPIEA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGU7-1", "uniprot_id": "Q9VGU7_DROME", "id": "Q9VGU7-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------MSSKVNFVFDSN---PLGLYQAGQLISGTAELITERPKTIRSIFITINGYGETRWQESEERVGE----------------------------------------DGKTTKSLVTHTTTEVYYSTDQPVYGQAGGS---------QLELPTGKYVFPFRATIPPN-APTSFNGAHGQIKHEVTLTIDRA-VRYNNTFKQCFTVILPHDLN-RRLEYKEPLQRLESKSFWWGSIFG--------------------------------------------------------AHKPMIMDVSTSY---------------------------------------------SAYVPGQKIHFHLVLDNQSDVQCMDVKVRLIKNVSYRANSSGAKEQLKVTESRVADKHCGEVLKHNKAKFDEF------------LTVPPTTP-STQSEKDPIRVSYTLRFIAKTFKLHGGGDLVMDFPITIGTVPLLGSADDKGPGAEKSQPSGASHPG-----------------------------------------------------------------------------SPNFQEDVSDEQFESNTFKPRYPVYPFDGKPGTNGSNGAANFPSLYPKAEEAHPATP------------------------VKFTPNPVSPAAQKSPPYTTNTP---------------VASPPGGNFEVLGFSIPPDYKPTPSAPAASSTGGIGWK-----------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1NYX2-1", "uniprot_id": "A0A8M1NYX2_DANRE", "id": "A0A8M1NYX2-1", "name": "", "aln": "------------MQRSIKELSVRYDPIN--ETNTFTNGDIVEGRVVLEVTKEINVENLFVKLTGDADVRWTEGSGD-------------------------------------------DERSYSDHERYFKQKQYFIQDSSKKGQCEKNTTLVSGETYGSVIKPGSHVFPFRFQLPQQNMPPTFKGFHGWVKYIVMVKLKRS--WKPTSSAQAEINFAPRNFG-TNDHLLQPQSGTEDKKMKLFGSG------------------------------------------------------------KMSMTVTTDK---------------------------------------------TGYMLGEIIRVSVDIDNSSSRDIKLKYSLKQLQTFIAGRSTTHA------HKDIVKETKDCIPSGGKTRFVVD------------IKLPHDIM-VTIENCRIIKVQYELKVYLDVSFAS---DPTVKFPVVIIPPLQQCPPWHDPPPPYMPPQP----------------------------------------------------------------------------------------NLVPYPGGAAPPPAGLYPNLYDPVPPYPGTAAGTFPNP-----------------------------------------NAMLPGFHPAPSAPVYDLN-----------------QSTKESFPNAPH------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGU4-1", "uniprot_id": "Q9VGU4_DROME", "id": "Q9VGU4-1", "name": "", "aln": "--------------MESERLRITLDS----ADRVYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEILRKNS-----------------------------------------NNNEYSRSLFYTSKEVYEHSETPLPDFEPRG----------LELSAGEHTFIFEVALGRQ-LPSSFKGSYGAIKYKMRVLIQRP-WTFDERHTIPFTVVKNMPLQPMQRSIPSSLEKQVTKTISLFGTR------------------------------------------------------------PITLLALLPE---------------------------------------------DFAVRGEPLRICATVINNS-TTAVEKLRFTVLQYVTYYSHVPLR-VQKVECIAVATKETGSVQKKTERSFAHE------------LLLPDGAQPTDEQMSGVITIVYELRVEAVLRGFFK--NLILNLPFKVYSQDPSNRQSSLRPPPPPRPNDGPPGPELGSGN------------------------------------------------LFEPALPVYPSLDSSIGSPSHSSQFSECSSINSITSDSSAATLSPAVGAGTGGMDMSYTSGSQSSQYGSPSARTSLRSSNVPYMPYSSSPLMVQSYPPPHLPAYPPPESPQYSLLALTPPPAGVVAAPPTG----------GAAAGGAPAYSQLPSTSASASFLQPRQAPGAHELPPSYEELFGLANAPPGTPK----------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7K7-1", "uniprot_id": "Q9I7K7_DROME", "id": "Q9I7K7-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------MSHRCEIQLDN----PRGVYRAGDTVNGHVYLTLSERALIKAICLEANGYASTAWQQPQKHKNQKKN-------------------------------------EQPVVVQSLDFDYRVDYFAKIDYFVGSEAAQP---------QIMEAGTYNYGFHVKLPKN-CPGNFEGGHGHIRYTLQVLIHSSADRPLEVLHVRQLQIFPQNSLSQETRSCEIQIYEQTPRLRFWMKP-------------------------------------------------------------LHLQLQIPR---------------------------------------------QGYSPGAGISVHLKLHNPE-KLTLREAVYSLVQISTYVAHLKNK-----PKRLETKVERQTVLSSRHELHNLPRGELQNFQHLHMLQVPQTAATLTVAGCACLQLNYEVEVLVTTQQEKR--LIAARMPVIIGNVTPPCPGKLLMQEPIDGTAPEPTPP-------------------------------------------------------------------------------------VETASTLIPNFSISTTSLASNFREAEFMVATNLNKT-----------------------------------------NKHYLSGEQLDFRPRYVYY----------------EMDQTQSEEVKSH------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02805-1", "uniprot_id": "ROD1_YEAST", "id": "Q02805-1", "name": "Protein ROD1", "aln": "MFSSSSRPSKEPLLFDIRLRNLDNDVLLIKGPPDEASSVLLSGTIVLSITEPIQIKSLALRLFGRLRLNIPTVLQTVHGPHKRYSKFERNIYSHFWDDFNIKSYFQNLYDNHNNGKITISSKSSTNLAALPKRKRALSTASLISSNGQTSASKN-----YHTLVKGNYEFPFSAIIPGSLVESVEGLPNAAVTYALEATIERP-KQPDLICKKHLRVIRTLAIDAVELSETVSVDNSWPEKVDYTISIPTKAIAIGSSTMINILIVPILKGLKLGPVRISLVENSQYCGSYGGVINQERMVAKLKLKDPLKHVAQIKKKRSLNEAADEGVDTDTGEFQDKWEVRALLNIPASLTKCSQDCRILSNIKVRHKIKFTISLLNPDGHISELRAALPVQLFISPFVPVNVKTSDVIERTLKTFGPSYQVTSQHDNSFSSKNFVDDSEED---VIFQRSASALQLSSMPTIVSGSTLNINSTDAEATAVADTTMVTSLMVPPNYGNHVYDRVYGEVTNEDETSASASSSAVESQAIHNIQNLYISDSNNSNNPILAPNPQIKIEDDSLNNCDSRGDSVNNSNLNLVNSNLTISENWNNNSPSANRYNNIINAGLNSPSLTPSFAHLSRRNSYSRQTSSTSLKNDLELTDLSRVPSYDKAMKSDMIGEDLPPAYPEEELGVQENKKIELERPQILHHKSTSSLLPLPGSSKSSNNLKRSSSRTHLSHSPLPRNNSGSSVSLQQLARNNTDSSFNLNLSFTSAKSSTGSRHFPFNMTTSFTSNSSSKNNSHFDKTDSTSDANKPREEENYTSATHNRRSRSSSVRSNNSNSPLRQGTGSFANLMEMFTKRDRS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : * . : . * . : : : . : . : : : . * : : .. : ", "identical_positions": 3, "similar_positions": 22, "identity": "0.35%" }, { "cls_id": "homologset.agr.SGD:S000005546", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JI95-1", "uniprot_id": "Q9JI95_MOUSE", "id": "Q9JI95-1", "name": "10 kDa heat shock protein, mitochondrial", "aln": "MAG--QAFRKFLLLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGGKGKSGE-IEPVSVKVGDKVLLPEYGGTKVVLD--DKDYFLFRDSDILGKYVN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64433-1", "uniprot_id": "CH10_MOUSE", "id": "Q64433-1", "name": "10 kDa heat shock protein, mitochondrial", "aln": "MAG--QAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGGKGKSGE-IEPVSVKVGDKVLLPEYGGTKVVLD--DKDYFLFRDSDILGKYVD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61604-1", "uniprot_id": "CH10_HUMAN", "id": "P61604-1", "name": "10 kDa heat shock protein, mitochondrial", "aln": "MAG--QAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGE-IQPVSVKVGDKVLLPEYGGTKVVLD--DKDYFLFRDGDILGKYVD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P26772-1", "uniprot_id": "CH10_RAT", "id": "P26772-1", "name": "10 kDa heat shock protein, mitochondrial", "aln": "MAG--QAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGGKGKGGE-IQPVSVKVGDKVLLPEYGGTKVVLD--DKDYFLFRDGDILGKYVD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2JVI0-1", "uniprot_id": "A0A0G2JVI0_RAT", "id": "A0A0G2JVI0-1", "name": "10 kDa heat shock protein, mitochondrial", "aln": "MAG--QVFRKSRLLPDRVLAERSVVVTVAKGGIMLPETTQGKVLQATIVVVGSGMKEKSEE-IQPVSVKVGDKVLLLEYGGTKAVLD--DKDYFLFRDGDILRKYVN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VU35-1", "uniprot_id": "Q9VU35_DROME", "id": "Q9VU35-1", "name": "10 kDa heat shock protein, mitochondrial", "aln": "MA---AAIKKIIPMLDRILIQRAEALTKTKGGIVLPEKAVGKVLEGTVLAVGPGTRNASTGNHIPIGVKEGDRVLLPEFGGTKVNLEGDQKELFLFRESDILAKLE--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFN5-1", "uniprot_id": "Q9VFN5_DROME", "id": "Q9VFN5-1", "name": "10 kDa heat shock protein, mitochondrial", "aln": "MS---NVIKKVIPMLDRILIQRFEVKTTTAGGILLPEESVPKEMQGVVVAVGPGARNPAGAGHLSVGVKEGDRVLLPKYGGTKVDMD-DKREYVLFRESDILAKLE--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38910-1", "uniprot_id": "CH10_YEAST", "id": "P38910-1", "name": "10 kDa heat shock protein, mitochondrial", "aln": "MSTLLKSAKSIVPLMDRVLVQRIKAQAKTASGLYLPEKNVEKLNQAEVVAVGPGFTDANGNKVVPQ-VKVGDQVLIPQFGGSTIKLG-NDDEVILFRDAEILAKIAKD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :. : **:* :* . : : .*: *** * :. ::.**.* . ** **:**: ::**:. : . : .***:.:** * ", "identical_positions": 27, "similar_positions": 31, "identity": "25.0%" }, { "cls_id": "homologset.agr.SGD:S000005548", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZSB2-1", "uniprot_id": "A0A8I5ZSB2_RAT", "id": "A0A8I5ZSB2-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNYPGRGAPRSPERNGRGGG--AWELGSDAAGVFGGGGCCFEHQPGDG-----VPLSLLRAEP-LHLAPGADDL-SHLALDPCLSDENYDFSSAESGSSLRYYSEGESAGGGS------------------SSSPPPP----LVAPNSGGGGAAGGGPGDRKRSRPGGCAARHRYEVVTELGPEEVRWFYKEDKKTWKPFIGYDSLRIELAFRSLLQTTGSRARSADRDGDRVCGPT----SSFRED-----------------DEDRACGFCPRAVGPEPEMEELVTIEPVCVRGGLYEVD-----------------------------------VTQGECYPVYWNQADKIPVMRGQWFIDGTWQPLEEEESNLIEQEHLSCFRGQQMQEN-FDIEMSKSIDGKDVVYHIPPFSLPSLFKWRGYKESTDATGLKRKRSQAVHSFKLSRNHVDWHS-------MDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLED---KPSQTSHIVFVVHGIGQKMDQ----GRIIKNTAMMREAARKIEEK-----HFAN-----HATHVEFLPVEWRSKLTLDGDTVDS------------ITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMMGWNPV-----------------------------------RLYEQLLQKEEELPDERWMS------------YEERHLLDELYITKRRLREIEDRLHGLK-----------------------------------------------------------------------------APSGSQTPALKFKVENFFCMGSPLAVFLALRGIRPG------NTGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYEHMKPNFLNPAKEPTSASESENIAAIPSPVTSPVLSRRHYGESITNIGKASILGAASIGKGLGGMLFSRFGRSSTPQPSEPSKDSAEEEKKPVSSPSTTTVATQTLPHSSSGFLDSAYFRLQESFFYLPQLLFPENVMQSKDDSLVELEHRIDFELREGLVESR--YWSAVTSHTAYWSSLDVALFLLTFMYKHEHDSEAKTSLDSI--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80YA3-1", "uniprot_id": "DDHD1_MOUSE", "id": "Q80YA3-1", "name": "Phospholipase DDHD1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLED---KPSQTSHIVFVVHGIGQKMDQ----GRIIKNTAMMREAARKMEEK-----HFSN-----HATHVEFLPVEWRSKLTLDGDTVDS------------ITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMMGWNPG-----------------------------------GLYEQLLQKEEELPDERWMS------------YEERHLLDELYITKRRLREIEDRLHGLK-----------------------------------------------------------------------------APSISQTPALKFKVENFFCMGSPLAVFLALRGIRPG------NSGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYEHMKPNFLNPAKEPTSVSDSENIAAIPSPVTSPVLSRRHYGESITNIGKASILGAASIGKGLGGMLFSRFGRSSASQPSEPSKDSLEDDKKPSASPSTTTVATQTLPHSGSGFLDSAYFRLQESFFYLPQLLFPENVMQSKDDSLVELEHRIDFELREGLVESR--YWSAVTSHTAYWSSLDVALFLLTFMYKHEHDTEAKPSLGSL--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NEL9-1", "uniprot_id": "DDHD1_HUMAN", "id": "Q8NEL9-1", "name": "Phospholipase DDHD1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNYPGRGSPRSPEHNGRGGGGGAWELGSDARPAFGGGVCCFEHLPGGDPDDGDVPLALLRGEPGLHLAPGTDDHNHHLALDPCLSDENYDFSSAESGSSLRYYSEGESGGGGS------------------SLSLHPPQQPPLVPTNSGGGGATGGSPGERKRTRLGGPAARHRYEVVTELGPEEVRWFYKEDKKTWKPFIGYDSLRIELAFRTLLQTTGARPQGGDRDGDHVCSPTGPASSSGEDD-----------------DEDRACGFCQSTTGHEPEMVELVNIEPVCVRGGLYEVD-----------------------------------VTQGECYPVYWNQADKIPVMRGQWFIDGTWQPLEEEESNLIEQEHLNCFRGQQMQEN-FDIEVSKSIDGKD----------------------------------AVHSFKLSRNHVDWHS-------VDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLED---KPSQTTHIVFVVHGIGQKMDQ----GRIIKNTAMMREAARKIEER-----HFSN-----HATHVEFLPVEWRSKLTLDGDTVDS------------ITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMTGWNPV-----------------------------------RLYEQLLQKEEELPDERWMS------------YEERHLLDELYITKRRLKEIEERLHGLK-----------------------------------------------------------------------------ASSMTQTPALKFKVENFFCMGSPLAVFLALRGIRPG------NTGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYEHMKPSFLNPAKEPTSVSENEGISTIPSPVTSPVLSRRHYGESITNIGKASILGAASIGKGLGGMLFSRFGRSSTTQSSETSKDSMEDEKKPVASPSATTVGTQTLPHSSSGFLDSAYFRLQESFFNLPQLLFPENVMQNKDNALVELDHRIDFELREGLVESR--YWSAVTSHTAYWSSLDVALFLLTFMYKHEHDDDAKPNLDPI--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80Y98-1", "uniprot_id": "DDHD2_MOUSE", "id": "Q80Y98-1", "name": "Triacylglycerol hydrolase DDHD2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSGES---------------------------------------------------------------------------------------------------------HQEQLSQSDPSPSPNSCSSFELIDMDAS----------------------------------------------SSYEPVSPHWFYCKVLDSKE-LWIPFNSEDSQQLEDAYGSGKDCNERIVP-TDGGR-YDVHLGERMRYAVYWDELPSEVRRCTWFYKGDKDNKYVPYSESFSQVLEDTYMLAVTLDEWKKKIESPNREIIVLHNPKLMVHYQPIAGSDEWGSTSTEQGRPRSVKRGVENIPVDIHCGEPLQIDHLVFVVHGIGPACDLR--FRSIVQCVNDFRSVSLNLLQT-----HFKKAQENEQIGRVEFLPVNWHSPL--HSTGVDIDLQ--------RITLPSINRLRHFTNDTILDVFFYNSPTYCQTIVDTVASEMNRIYTLFLQRNPDFK---GGVSIAGHSLGSLILFDILTNQK-----NSIGDIDSEK----------------------GSLSSAEDRGDASTLEEDLKKLQLSEFVTVFEKEKVDREALALCTDRDLQEMGIPLGPRKKILNHFSARKNSVSINRPA-------------------------MSASEVNISKE-------------NGDYLDVGIGQVSVKYPRLNYKPEIFFAFGSPIGMFLTVRGLRR---------IDPNYKFP--TCKGFFNIYHPFDPVAYRIEPMVAPGIE-FEPMLIPHHKGRKRMHLELREG--------------------------------------------LTRMSMDLKNNLLGSLRMAWKS---FTRGPYPALQASETAEETEAEPESSSEK--SNEAN-----------------TEEPPVEVKEEA-PISVGMLNGGQRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTVLLVLKEIYQTQGVFLDQPLQ-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZJ91-1", "uniprot_id": "D3ZJ91_RAT", "id": "D3ZJ91-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSGES---------------------------------------------------------------------------------------------------------YQEQLSQSDPSPSPNSSSSFELLDMDVG----------------------------------------------SSYEPVSPHWFYCKVIDSKE-LWIPFNSEDSQQLEEAHGSGKDCNERVVP-TDGGR-YDVHLGERMRYAVYWDELPSEVRRCTWFYKGDKDNKYVPYSESFSQVLEDTYMLAVTLDEWKKKLESPNREIIVLHNPKLMVHYQPITGSDEWGSTSTEQGRPRSVKRGVESIPVDIHCGEPLQIDHLVFVVHGIGPACDLR--FRSIVQCVNDFRSVSLNLLQT-----HFKKAQENQQIGRVEFLPVNWHSPL--HSTGVDIDLQ--------RITLPSINRLRHFTNDTILDVFFYNSPTYCQTIVDTVASEMNRIYTLFLQRNPDFK---GGVSIAGHSLGSLILFDILTNQK-----DSIGDIDSEK----------------------GSLSTAEDLGDVSTLEEELKKLQLSEFVTVFEKEKVDREALALCTDRDLQEMGIPLGPRKKILNHFSATKSSVGINRPT-------------------------MSASEVNIPKE-------------KGDYLDVGIGQVSVKYPRLNYKPEIFFAFGSPIGMFLTVRGLRR---------IDPNYKFP--TCKGFFNIYHPFDPVAYRIEPMVVPGVE-FEPMLIPHHKGRKRMHLELREG--------------------------------------------LTRMSMDLKNNLLGSLRMAWKS---FTRAPYPALQASEMAEDTEAESEPSSEK--PSDAN-----------------TEEPPVEVKEEA-PINVGMLNGGQRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTVLLVLKEIYQTQGIFLDQPLQ-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O94830-1", "uniprot_id": "DDHD2_HUMAN", "id": "O94830-1", "name": "Triacylglycerol hydrolase DDHD2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSVQS---------------------------------------------------------------------------------------------------------QQEQLSQSDPSPSPNSCSSFELIDMDAG----------------------------------------------SLYEPVSPHWFYCKIIDSKE-TWIPFNSEDSQQLEEAYSSGKGCNGRVVP-TDGGR-YDVHLGERMRYAVYWDELASEVRRCTWFYKGDKDNKYVPYSESFSQVLEETYMLAVTLDEWKKKLESPNREIIILHNPKLMVHYQPVAGSDDWGSTPTEQGRPRTVKRGVENISVDIHCGEPLQIDHLVFVVHGIGPACDLR--FRSIVQCVNDFRSVSLNLLQT-----HFKKAQENQQIGRVEFLPVNWHSPL--HSTGVDVDLQ--------RITLPSINRLRHFTNDTILDVFFYNSPTYCQTIVDTVASEMNRIYTLFLQRNPDFK---GGVSIAGHSLGSLILFDILTNQK-----DSLGDIDSEK----------------------DSLNIVMDQGDTPTLEEDLKKLQLSEFFDIFEKEKVDKEALALCTDRDLQEIGIPLGPRKKILNYFSTRKNSMGIKRPAP------------------------QPASGANIPKESEFC---SSSNTRNGDYLDVGIGQVSVKYPRLIYKPEIFFAFGSPIGMFLTVRGLKR---------IDPNYRFP--TCKGFFNIYHPFDPVAYRIEPMVVPGVE-FEPMLIPHHKGRKRMHLELREG--------------------------------------------LTRMSMDLKNNLLGSLRMAWKS---FTRAPYPALQASETPEETEAEPESTSEK--PSDVN-----------------TEETSVAVKEEVLPINVGMLNGGQRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTVLLVLKEIYQTQGIFLDQPLQ-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NZC7-1", "uniprot_id": "S23IP_MOUSE", "id": "Q6NZC7-1", "name": "SEC23-interacting protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADRKANGG--GASASSSGTNLLFSSSATEFSFN-------VPFIPVTQAAASPASLLLPGEDSTDVGEEDSFLG--------QTSTHTSTPQTFSYF-----------------------SQVSSSSDPFGNIGQSPLTTSAMSAGQSALPKPPATLAFTTGSQDALSAFPPSVSKAP-GATPPSQMGTSTYSPSQPSSLPPN-FGSPPQGIPQQGHNPYRHTPVSSRANPYITPP----------------QLQQCQMPGHSSYPPPSGPPVQTYQMPPGPLPPLPTAMQSPAQQQVPARPAGPLVQGPSPFV-----------LQNQYEPVQPHWFYCKEVEYKQ-LWMPFSVLDSLNLEEIYNSVQPDPESVVLGTDGGR-YDVYLYDRMRKSVYWEEEPTEVRRCTWFYKGDTDSRFIPYTEEFSEKLEAEYKKAVSTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWGTTQDGQTRPRVVKRGIDDSLDEIPDGEMPQVDHLVFMVHGIGPVCDLR--FRSIIECVDDFRVVSLKLLQT-----HFKKSVDEGKVSRVEFLPVHWHSALGGHATGVDRNIK--------KITLPSIGRFRHFTNETLLDVLFYNSPTYCQAIVEKVEVEINRLHSLFMSRNPNFK---GKVSVAGHSLGSLILFDILSNQRDMCVSKSPGSVAVSNGVIKHSQFQEKLISEESKLMSDESCDLDVEDEEPLTLHGTLEALSLFDYISTFEKEKIDMESLLMCTVDDLKEMGIPLGPRKKIANFVKLKAAKLEQKKAAAEKKAALAALTKGQDESAPKTKEMASPSSESNESKRKLSVGAYVSSVRVDYESFEVGTGQVSVAYSSLDFEPEIFFALGSPIGMLLTIRGVAR---------IDEKYRLP--TCKGFFNIYHPLDPVAYRLEPMIAPDLD-LKAVLVPHHKGRKRLHLELKES--------------------------------------------LSRMGSDLKQGFISSLKSAWQTLNEFARAHTSTTQLQEELEKVANQIKEEEEKQVVEAKK-----------------KKESPELSKDEDYLGKVGMLNGGRRIDYVLQEKPIESFNEYLFALQSHLCYWGSEDTALLLLKEIYRTMNISPEQPQH-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V8Q8-1", "uniprot_id": "G3V8Q8_RAT", "id": "G3V8Q8-1", "name": "SEC23-interacting protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADRKANGG--GASASSSGTNLLFSSSATEFSFN-------VPFIPVTQAAASPASLLLPGEDSTDVGEEDSFLG--------QTSTHTSTPQTFSYF-----------------------SQVSSSSDPFGNIGQSPLATTAMSAGQSALPKPPATLPFTTGSQDMLNAFPPSVSKAPYGAAPSSQMGASTYLPSQPSSLPPN-FGSPPQGIPQQGHNPYRHTPVSSRANPYITPP----------------QLQQCQTPGHPSYPPPSAPPVQTYQMPPGPLPPLPTAVQSPAQQQVPARPAGPLVQGPSPFV-----------LQNQYEPVQPHWFYCKEVEYKQ-LWMPFSVLDSLNLEEIYNSVQPDPENVVLGTDGGR-YDVYLYDRMRKSVYWEEEPAEVRRCTWFYKGDTDSRFIPYTEEFSEKLEAEYKKAVTTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWGTTQDGQTRPRVVKRGIDDNLDEIPDGEMPQVDHLVFMVHGIGPVCDLR--FRSIIECVDDFRVVSLKLLQT-----HFKKSVDEGKVSRVEFLPVHWHSALGGHATGVDRNIK--------KITLPSIGRFRHFTNETLLDVLFYNSPTYCQSIVEKVGVEINRLHSLFMSRNPNFK---GKVSVAGHSLGSLILFDILSNQKDMSISKSPGSVAVSNGVTKHSNFQEKQVSEESKLMSDESCDLDVEDEEPLTLHGTLEALSLFDYISTFEKEKIDMESLLMCTVDDLKEMGIPLGPRKKIANFVKLKAAKLEQKKAASEKKAALAALTKGQGESAPKTKEMASPSSESNESKRKLSVGAYVSSVRVDYESFEVGTGQVSVAYSSLDFEPEIFFALGSPIGMFLTIRGVDR---------IDESYRLP--TCKGFFNIYHPLDPVAYRLEPMIAPDLD-LKAVLIPHHKGRKRLHLELKES--------------------------------------------LSRMGSDLKQGFISSLKSAWQTLNEFARAHTSSTQLQEELEKVANQIKEEEEKQVVEAEK-----------------IVESPEFSKDEDYLGKVGMLNGGRRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTALLLLKEIYRTMNISPEQPQH-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6Y8-1", "uniprot_id": "S23IP_HUMAN", "id": "Q9Y6Y8-1", "name": "SEC23-interacting protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAERKPNGGSGGASTSSSGTNLLFSSSATEFSFN-------VPFIPVTQASASPASLLLPGEDSTDVGEEDSFLG--------QTSIHTSAPQTFSYF-----------------------SQVSSSSDPFGNIGQSPLTTAATSVGQSGFPKPLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPP----------------QLQQCQTPGPPAHPPPSGPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVPSPFL-----------LQNQYEPVQPHWFYCKEVEYKQ-LWMPFSVFDSLNLEEIYNSVQPDPESVVLGTDGGR-YDVYLYDRIRKAAYWEEEPAEVRRCTWFYKGDTDSRFIPYTEEFSEKLEAEYKKAVTTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWGTTQDGQTRPRVVKRGIDDNLDEIPDGEMPQVDHLVFVVHGIGPVCDLR--FRSIIECVDDFRVVSLKLLRT-----HFKKSLDDGKVSRVEFLPVHWHSSLGGDATGVDRNIK--------KITLPSIGRFRHFTNETLLDILFYNSPTYCQTIVEKVGMEINHLHALFMSRNPDFK---GGVSVAGHSLGSLILFDILSNQKDLNLSKCPGPLAVANGVVKQLHFQEKQMPEEPKLTLDESYDLVVENKEVLTLQETLEALSLSEYFSTFEKEKIDMESLLMCTVDDLKEMGIPLGPRKKIANFVEHKAAKL--KKAASEKKAVAATSTKGQEQSAQKTKDMASLPSESNEPKRKLPVGACVSSVCVNYESFEVGAGQVSVAYNSLDFEPEIFFALGSPIAMFLTIRGVDR---------IDENYSLP--TCKGFFNIYHPLDPVAYRLEPMIVPDLD-LKAVLIPHHKGRKRLHLELKES--------------------------------------------LSRMGSDLKQGFISSLKSAWQTLNEFARAHTSSTQLQEELEKVANQIKEEEEKQVVEAEK-----------------VVESPDFSKDEDYLGKVGMLNGGRRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTALLLLKEIYRTMNISPEQPQH-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLS7-1", "uniprot_id": "Q9VLS7_DROME", "id": "Q9VLS7-1", "name": "", "aln": "MSERSKGDVSARVNNNANQTRVVKNPLLSASVTGLSFDDFPNKPQLLPAAPPVVHATPPAAPVLIAGILNREPKSLVTVGQPSSIDDSEALDEINLNTSSEDSVGAGGSSPYLGAGDQNANPLLEPPTEAGNDSLLSQAASSFTALPAVASNVFSTFSKRIYAGSRETSEEPKLDIQPSYIQQASYVQPVAPVPAPFYAAPPAAANEVVAPEPPKFYAPTEVPPPNVGVPAPPPTSGNPNTYRFTARKKLYAPIPGLSEQSGQPAQQPQVPQAPQAAPSFQTPPYPPQLTYAANPAPFDISAQPAAIPAEERKSGGGLFSLTSLVPTGVLQNITGIVQSATGRSSEPEHTNVQQAGGYLDITTASAPAPSTNLFGGPNSTFPPGGNYFVPGAPPSLPSTGVVGPPSVGNFFAPAAPLPVAQTAAPPAVGAFFTSAAPSVTPSVFTPGTVPPLAPQPFQSATVNQSALPPNNPPTASAVGELFVPAPTTIAQGTSPAVPFVDTQAVPTIPLTVPPGNPPPTSTLGGFFTTGEVAPVVAPFGTQASPATQSAGFFNPGEVRPNVPLAEPVPTIPITSSGVPPIGLFPPAPAQPGVQTASNPNPLPGAAAPPPAAGQASYRLQKGTRLYKSPLTPQETATSSGFAAPLPPTSVTPAIFNPFGAPAPGSFNSVGHLEGQSSQGVPFFTPPVQNPPGQVAAPTVAVPQSAPIAPPPGTSSTSVAPPLTASIANPPPTSGFASVPLFAAPTISSTPIPFFNPQPTGAEVTTGLSQQENEATASTTLEGLVQGPAPTLSASQFFDTPLPTGTQPENQVASVSSERENLVQEPISNQGIPFFAPPQTNIFTPQLQQEFIAPAEDSKRSEIQEEFLSAPPQESNLSTELREDTHTGPPVIEPVLEETPASSSESSVPPASKVDQEDIVYPEPSAPVEQEIPLFVPVPGLPGLSQDIPLYPPPPTGSTTASSIFAAPPVASSAPLFVPVPGPPSVSSLFSPSQVDSTSSLFAPPPTSANTTILTPAPDTTSTLFANNIPTTTPSIPDIVPTTSAELVDAPPGFQGSSDDTATNLFQGNTETQTVFSPFAQTKATPLVQETKPELVPPPIGFFAPKSESEVLSQPPLAPSPLQSFFSTAPETATTTDFNFFGSPAPGSVFPDLPVQQGIAPPPLALESPPQNSVSNIATSAIGFDLLNQTQQASSLVENSNQNSSVNSFDGYFGGPSASAAQTFANETTNALVAPAINCDPVNFFDQVPQTQSQIQQANEDQRIQNFFNNPPLQDQPAVPGELKYDIVHSGVAVKQLQERSQTPVSNLVEPPSSACSEFSTLAPAPTQTDRQSGDDLLQQHLGELPEDILRELRMASASSEKGQVATPPVAIPYSPVVAHWFYKRSVDTKF-IWTPFSHYDSALLETSLN---LDDSTLIIPVEGGR-YDVNIKERTKTPVYWEGKAIEVRRCSWFYKG-VDSKYVPYTEDTAALLEAEYKRSAETGEWHQKIMLANGEQVVFHGPTVIVHFLPQQNADTWGASTQGSMRPRVVKRDLDDFTIEQ--GESQRVDHLLFMVHGIGSACDLK--MRSVEEVVDDFRVIAQQLVQS-----HYKNSTDMGLVGRVEVLPISWHGHLHSEELGIDEKLK--------SITLESIPRLRNFTNDTLLDVLFYTSPKYCQKIMNTVADALNDVYLKYRMRHPEFN---GGVSLAGHSLGSLILFDLLCHQEPLK----------------------------------ESEEENKENPDQLPQKQSSQKVQLP------------------TSDPLPKQVSYAMGPE----------------------------------------------------------------------------GTGQPVITYTQLIFHPKKFFALGSPIGMFVTIRGIDK---------LGLDFHLP--TCPGFYNIFHPFDPVAYRIEALVNPDMNGIRPVLIPHHKGRKRMHLELKET--------------------------------------------MTRVGADIKQRFMDTFKTTLDSVNFLTTVTKVKKEAEESLEKETSQTSSQAFQKQTEDQDESSVASSSCKLRNRTDSNSTTASDPEFIELDFPLGKLNDSKRVDYVLQEAPLEFINEYIFALSSHVCYWGSEDTILFVMKEIYASLGISTDSQVPQSSMTIERPVSHESSVSHSLLPM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12204-1", "uniprot_id": "YOR22_YEAST", "id": "Q12204-1", "name": "Probable phospholipase YOR022C, mitochondrial", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRFTHRGLPSSTRFRNIFVRLNHIYVPWFYAIDVPNSKPYLPTYQTLHSPKKFKPFSVDDSNRLEKASKRQERRPVLVNEDYLFKVDLSHMELSPTYWEG-----------------PTYQVRRGVWFDSSNQPLSSDLTSEIEGLYKQLK---------------------------------------------------------------------------------------------------FDDSNDDPTTTPPAESQDIFRLKGKYPVD---------------------------------------------KENEGEQKNGSSNKDENESTFKFILFANKQTAFLLSDLDGGKLQLAFLRSNLAQSLPINATMITRSYKYSSSATTKQTSTSFKAAKTPQTEVADGSNSSKSRSIETKLEKKVSNLFNLSDFLQLFNGNASKDQDDAQSLEKQMETDYNNADNSQGANASSKIEDGKNSGASDRQIRSNRRDVDNLILCVHGIGQTLGKKYEYVNFAHTVNLLRSNMKKIYNNSEKLQSLNTAPDYKSNCNVQVLPITWRHSISFQTDAKEENIENPDLPTLSQVTVNGVLPLRKLLADGLLDILLYVEPYYQDMILQQVTSQLNKTYRIFKEFNPEFD---GKVHLVGHSLGSMILFDILSKQK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KYELEFQVDNLFFIGSPIGLLKLIQRTKIGDRPEFPNDLERKLTVQRPQCKDIYNVYHVCDPISYRMEPLVSKEMAHYEQTYLPHCSEAYGLTSKVLEFG--------------------------------------------ENIWKDLPGTDENNLQSKKTS------PEKKEVKLSENLTRMLTG--------------------------------------------------LNYTGRLDYAMSPSLLEVD--FISAIKSHVSYFEEPDIAAFILKEILSKHENASEIYVKRKTG-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . .: . : :::: ***** . . . . :* :: . . .*:.**: *: : . : :* : :*.: . :*:: * .* * : ::. : :* : : :*:*. * * :..****.:* :*:: . * :. . :* :***:.:: :: . . * : *::* **::**:*.:: : . : : : : . : . * :: *:*: : :* : *: ** .*: . * :::. : ", "identical_positions": 49, "similar_positions": 106, "identity": "2.2%" }, { "cls_id": "homologset.agr.SGD:S000005552", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43684-1", "uniprot_id": "BUB3_HUMAN", "id": "O43684-1", "name": "Mitotic checkpoint protein BUB3", "aln": "-----------------------MTGSNEFKLNQPPEDGISSVKFSPNTSQFLLVSSWDTSVRLY--DVPAN--SMRLKYQHTGAVLDCAFYD---PTHAWSGGLDHQLKMHDLNTDQENLVGTHDAPIRCVEYCPEVN-VMVTGSWDQTVKLWDPR--------TPCNAGTFSQPEK-VYTLSVSGDRLIVGTAGRRVLVWDLRNM-GYVQQRRESSLKYQTRCIRAFPN-KQGYVLSSIEGRVAVEYLDPSPE--VQKKKYAFKCHRLKENNIEQIYPVNAISFHNIHNTFATGGSDGFVNIWDPFNKKRLCQFHRYP-TSIASLAFSNDGTTLAIASSYMYEMDDT--EHPEDGIFIRQVTDAETKPKSPCT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WVA3-1", "uniprot_id": "BUB3_MOUSE", "id": "Q9WVA3-1", "name": "Mitotic checkpoint protein BUB3", "aln": "-----------------------MTGSNEFKLNQPPEDGISSVKFSPNTSQFLLVSSWDTSVRLY--DVPAN--SMRLKYQHTGAVLDCAFYD---PTHAWSGGLDHQLKMHDLNTDQENLVGTHDAPIRCVEYCPEVN-VMVTGSWDQTVKLWDPR--------TPCNAGTFSQPEK-VYTLSVSGDRLIVGTAGRRVLVWDLRNM-GYVQQRRESSLKYQTRCIRAFPN-KQGYVLSSIEGRVAVEYLDPSPE--VQKKKYAFKCHRLKENNIEQIYPVNAISFHNIHNTFATGGSDGFVNIWDPFNKKRLCQFHRYP-TSIASLAFSNDGTTLAIASSYMYEMDDT--EHPEDGIFIRQVTDAETKPKST----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A567-1", "uniprot_id": "D4A567_RAT", "id": "D4A567-1", "name": "", "aln": "MAAGLDQGGPARCAGAGPAFVLQMTGSNEFKLNQPPEDGISSVKFSPNTSQFLLVSSWDTSVRLY--DVPAN--SMRLKYQHTGAVLDCAFY-------------------------VENLVGTHDAPIRCVEYCPEVN-VMVTGSWDQTVKLWDPR--------TPCNAGTFSQPE--------------------------------------------------------KGYVLSSIEGRVAVEYLDPSPE--VQKKKYAFKCHRLKENNIEQIYPVN-----------------------------RLCQFHRYP-TSIASLAFSNDGTTLAIASSYMYEMDDT--EHPEDGIFIRQVTDAETKPKSSRKSSVNICGLSQDGHRLAASSWRLAVPGLWSSRIPVLTIPPSADTAKRQAPLDIATNCYSKFPDVHTAVTLVASMHKSRTGVITLLVFVTTYLMRSTIKEESLLLLVVKGGKVHHGGEGKSGSPKSQKHFLLALQFFIWHNSNSNNNNNSNNNNSNNNNSNNNNNSNNSSSNNSNSNNSNSNNSSSNSTSNNSNSNNSNSNNSNNNNNNSNNSNSNNSNSNSNNSNNKNSNNNSNNNNSNSNSNNSNNSSNNSSSSNNSNSNNNSNNSNNSNNSSNNSSSSNNSNNKNNSNNNNSNNNNNSNSSSSNNNSNSNNNSNSSSSNNNSSSNNNSNNNSNNNSNSNNHHHHPGNLAAAPLICIGIFLLLQALKGLNDTML", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VAJ2-1", "uniprot_id": "Q9VAJ2_DROME", "id": "Q9VAJ2-1", "name": "Mitotic checkpoint protein BUB3", "aln": "------------------------MRPPEFKLNNPPEDLISAVKFGPKSNQYMAASSWDGTLRFY--DVPAN--QLRQKFVQDAPLLDCAFMD---IVHVVSGSLDNQLRLFDVNTQAESIIGAHEEPIRCVEHAEYVN-GILTGSWDNTVKLWDMR--------EKRCVGTFEQNNGKVYSMSVIDEKIVVATSDRKVLIWDLRKM-DSYIMKRESSLKYQTRCIRLFPN-KEGYVMSSIEGRVAVEYLDHDPE--VQRRKFAFKCHRNREQNIEQIYPVNALSFHNVYQTFATGGSDGIVNIWDGFNKKRLCQFHEYD-TSISTLNFSSDGSALAIGCSYLDQLPETPATVPHPAIYIRYPTDQETKQK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P26449-1", "uniprot_id": "BUB3_YEAST", "id": "P26449-1", "name": "Spindle assembly checkpoint protein BUB3", "aln": "--------------------------MQIVQIEQAPKDYISDIKIIPSKS-LLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLCEDDNGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDNILCLATSDDTFKTNAAIDQTIELNASSIYIIFDYEN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::::.*:* ** :*: *... : :*** :: .* *: *: .: . .:* * * . : :: : . . : :::.*** ::: * * .. : : :**. ***:******::* . : . :::**:*** . :: : **** :: :* .: *: .: *.: ** . . : . * * *. ", "identical_positions": 49, "similar_positions": 74, "identity": "6.54%" }, { "cls_id": "homologset.agr.SGD:S000005553", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60864-1", "uniprot_id": "STIP1_MOUSE", "id": "Q60864-1", "name": "Stress-induced-phosphoprotein 1", "aln": "-MEQVNELKEKGNKALSAGNIDDALQCYSEAIKLDPQ-NHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNLQLKEGLQNMEARLAERKFMNPFN------LPNLYQKLENDPRTRSLLSDPTYRELIEQLQNKPSDLGTKLQ-DPRVMTTLSVLLGVDLGSMDEEEEAATPPPP----------------------------PPPKKEPKPEPMEEDLPENKKQALKEKELGNDAYKKKDFDKALKHYDRAKELDPTNMTYITNQAAVHFEKGDYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPRDAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADG------YQRCMMAQYNRHDS---PEDVKRRAMADPEVQQIMSDPAMRLILEQMQKDPQALSEHLKNPVIAQKIQKLMDVGLIAIR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35814-1", "uniprot_id": "STIP1_RAT", "id": "O35814-1", "name": "Stress-induced-phosphoprotein 1", "aln": "-MEQVNELKEKGNKALSAGNIDDALQCYSEAIKLDPQ-NHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNLQLKEGLQNMEARLAERKFMNPFN------LPNLYQKLENDPRTRTLLSDPTYRELIEQLQNKPSDLGTKLQ-DPRVMTTLSVLLGVDLGSMDEEEEAATPPPP----------------------------PPPKKEAKPEPMEEDLPENKKQALKEKELGNDAYKKKDFDKALKHYDKAKELDPTNMTYITNQAAVHFEKGDYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEERYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPRDAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADG------YQRCMMAQYNRHDS---PEDVKRRAMADPEVQQIMSDPAMRLILEQMQKDPQALSEHLKNPVIAQKIQKLMDVGLIAIR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31948-1", "uniprot_id": "STIP1_HUMAN", "id": "P31948-1", "name": "Stress-induced-phosphoprotein 1", "aln": "-MEQVNELKEKGNKALSVGNIDDALQCYSEAIKLDPH-NHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLKEGLQNMEARLAERKFMNPFN------MPNLYQKLESDPRTRTLLSDPTYRELIEQLRNKPSDLGTKLQ-DPRIMTTLSVLLGVDLGSMDEEEEIATPPPP----------------------------PPPKKETKPEPMEEDLPENKKQALKEKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADG------YQRCMMAQYNRHDS---PEDVKRRAMADPEVQQIMSDPAMRLILEQMQKDPQALSEHLKNPVIAQKIQKLMDVGLIAIR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPN5-1", "uniprot_id": "Q9VPN5_DROME", "id": "Q9VPN5-1", "name": "Stress-induced-phosphoprotein 1", "aln": "-MDKVNELKEKGNQALSAEKFDEAVAAYTEAIALDDQ-NHVLYSNRSAAFAKAGKFQEALEDAEKTIQLNPTWPKGYSRKGAAAAGLNDFMKAFEAYNEGLKYDPTNAILLQG--RMETTASALSFMQSQGD-----IP-----MDVDPQQ-------------ARSRRAPS------------------------------PPPAKPAEP----------------------------PKP-AEPRVEDMTEEQ-KNKYFARKEKELGNAAYKKKDFETALKHYHAAIEHDPTDITFYNNIAAVHFERKEYEECIKQCEKGIEVGRESRADFKLIAKSFARIGNTYRKLENYKQAKVYYEKAMSEHRTPEIKTSLSEVEAKIKEEERMAYINPEKAEEEKEQGNLFFKKGDYSTAVKHYTEAIKRNPDDPKLYSNRAACYTKLAAFDLGLKDCDTCIKLDEKFIKGYIRKGKILQGMQQQSKAQAAYQKALELDPNNAEAIEG------YRQCSMN-FQRN-----PQEVLKNAMSDPEIQQILKDPAMRMILEQMQSDPNAVKEHLQNPAIADKIMKLLESGIIQIH-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15705-1", "uniprot_id": "STI1_YEAST", "id": "P15705-1", "name": "Heat shock protein STI1", "aln": "MSLTADEYKQQGNAAFTAKDYDKAIELFTKAIEVSETPNHVLYSNRSACYTSLKKFSDALNDANECVKINPSWSKGYNRLGAAHLGLGDLDEAESNYKKALELDASNKAAKEGLDQVHRTQQARQAQPDLGLTQLFADPNLIENLKKNPKTSEMMKDPQLVAKLIGYKQNPQAIGQDLFTDPRLMTIMATLMGVDLNMDDINQSNSMPKEPETSKSTEQKKDAEPQSDSTTSKENSSKAPQKEESKESEPMEVDEDDSKIEADKEKAEGNKFYKARQFDEAIEHYNKAWELH-KDITYLNNRAAAEYEKGEYETAISTLNDAVEQGREMRADYKVISKSFARIGNAYHKLGDLKKTIEYYQKSLTEHRTADILTKLRNAEKELKKAEAEAYVNPEKAEEARLEGKEYFTKSDWPNAVKAYTEMIKRAPEDARGYSNRAAALAKLMSFPEAIADCNKAIEKDPNFVRAYIRKATAQIAVKEYASALETLDAARTKDAEVNNGSSAREIDQLYYKASQQRFQPGTSNETPEETYQRAMKDPEVAAIMQDPVMQSILQQAQQNPAALQEHMKNPEVFKKIQTLIAAGIIRTGR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:* *::** *::. . *.*: :::** :. **********.::. .:..* :*. : :.::* * ***.* .** *. : :* *::.*: :..* :* .:. . . * :. :*: :. *. : * * * . . * * : ..* * *** ** ** ::*: *::**. * * . .::*: .* **. :*: :*: . . :..:* *** * *:: *:*::*****:* * *.: :*:*:::****.:: .. :.* :*: * **:**: * * : :*: * *.*:. *:* *** *** * *.: ******. :** * .: **: .*: : .*::.* **. .::: :.* . : * *.. :. .. * :. :: *::. :.** ***: *:.**.*: **:* *.:* *:.**::** : .** .*: *:* ", "identical_positions": 154, "similar_positions": 170, "identity": "26.1%" }, { "cls_id": "homologset.agr.SGD:S000005558", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3U1N2-1", "uniprot_id": "SRBP2_MOUSE", "id": "Q3U1N2-1", "name": "Sterol regulatory element-binding protein 2", "aln": "------MDESSELGVLETMETLTELGDELTLGDIDEMLQFVSNQVGEFPDLFSEQLCSSFPGGGSNG----GSG---NNSSGRGNNGGATDPAVQRSFSQVPLSTFSPSAASPQAPALQVKVS----PTPPRATPVLQPRPQPQPQPP------------AQLQQQTVMITPTFSTAPQTRIIQQPLIY-QNAATSFQVLQPQVQSLVTSPQVQPVTIQQQVQTVQAQRVLTQTANGTLQTLAPATVQTVAAPQVQQVPVLV-QPQIIKTDSLVLTTLKTDGSPVMAAVQNP-ALTALTAPIQTAALQVPTLVGSNGTILTTMPVMMGQ-EKVPIKQVPGG-----------VKQLDPP------KEGERRTTHNIIEKRYRSSINDKIIELKDLVMGTDAKMHKSG-----VLRKAIDYIKYLQQVNHKLRQENMVLKLANQKNKLLKGIDLGSL------VDSDVDLKIDDFNQNVLLMSPPASDSGSQ--AGFSPYSIDSEPGSPLLDDAKVKDEP------DSPPVALGMVDRSRILLCVLTFLGLSFNPLTSLLQWGGAHNTDQHPYSGSGRSVLSLESGA---GGWFDWMVPTLLLWLVNGVIVLSVFVKLLVHGEPVIRPHSRPSVTFWRHRKQADLDLAKGDFAAAAANLQTCLSVLGRALPTSRLDLACSLSWNVIRYSLQKLRLVRWLLKKVFQRWRATPATAAGFEDEAKSSARDAALAYHRLHQLHITGKLPAGSACSDVHMALCAVNLAECAEEKILPSTLIEIHLTAAMGLKTRCGGKLGFLAS-YFLNRAQSL-CGPEHSTVPDSLRWLCHPLGQKFFMERSWS---IKSAAKESLYCAQRSPADPIAQVHQAFCKNLLERAVESLVKPQAKKKAGDQEEESCEFSSALEYLKLLHSFVDSVGFVTSPFSSSSVLRSALGPDVICRWWTSAVTMAISWLQGDDAAVRSRFTEVERVPKALEVTES----PLVKAVFYTCRAMHASLSG-KADGQQNSFC--HCERASGHLWSSLNVSGTTSDPSLNHVIQLFTCDLLLSLRTALWQKQASASQLLGETYHASGTELAGFQRDLGSLRRLAHSFRPAYRKVFLHEATVRLMAGASPTRTHQLLEHSLRRRPT------QNTKHGEVDTWPGQRERATAILLACRHLPLSFLSSPGQRAVLLAEAARTLEKVGDRRSCSDCQQMIVKLGGGTAIAAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3T1I5-1", "uniprot_id": "SRBP2_RAT", "id": "Q3T1I5-1", "name": "Sterol regulatory element-binding protein 2", "aln": "------MDENSELGGLETMETLTELGDELTLGDIDEMLQFVSNQVGEFSDLFSEQLCSSFPGGGGGS----GSGGTSNNSSGRGTSGGAADPAVQRSFSQVPLSTFSPSSTSPQAPALQVKVS----PTPPRATPVLQPRPQPQPQPP------------AQLQQQTVMITPTFSTAPQTRIIQQPLIY-QNAATSFQVLQPQVQSLVTSSQVQPVTIQQQVQTVQAQRVLTQTANGTLQTLAPATVQTVATPQVQQVPVLV-QPQIIKTDSLVLTTLKTDGSPVMAAVQNP-ALTALTAPIQTAALQVPTLVGSNGAILTTMPVMMGQ-EKVPIKQVPGG-----------VKQLEPP------KEGERRTTHNIIEKRYRSSINDKIIELKDLVMGTDAKMHKSG-----VLRKAIDYIKYLQQVNHKLRQENMVLKLANQKNKLLKGIDLGSL------VDSDVDLKIDDFNQNVLLMSPPASDSGSQ--AGFSPYSIDSEPGSPLLDDAKVKDEP------DSPPVALGMVDRSRILLCVLTFLGLSFNPLTSLLQWGGAHNPDQHPYSGSGRNVLSLESGS---GGWFDWMMPTLLLWLLNGVIVLSVFVKLLVHGEPVIRPHSRSSVTFWRHRKQADLDLAKGDFAAAAANLQTCLSVLGRALPTSRLDLACSLSWNVIRYSLQKLRLVRWLLKKVFQRWRATPATAAGFEDEAKSSARDAALAYHRLHQLHITGKLPAGSACSDVHMALCAVNLAECAEEKIPPSTLVEIHLTAAMGLKTRCGGKLGFLAS-YFLNRAQSL-CGPEHSAVPDSLRWLCHPLGQKFFMERSWS---IKSAAKDSLYCAQRNPADPIAQVHQAFCKHLLERAVEALVKPQAKKKAGDREEESCEFSSALEFLKLLHSFVDSVGFVASPFSSSSVLRSALGPDVVCRWWTSAITVAISWLQGDDAAVRSHFTEVERVPKALEVTES----PLVKAVFYACRAMHASLSG-KADGQQNSFC--HCERASGHLWSSLNVSGTTSDPSLNHVVQLLTCDLLLSLRTTLWQKQASASQLLGETYHASGTELAGFQRDLGSLRRLAHSFRPAYRKVFLHEATVRLMAGASPTRTHQLLEHSLRRRTT------QNTKHGEVDTWPGQRERATAILLACRHLPLSFLSSPGQRAVLLAEAARTLEKVGDRRSCSDCQQMIVKLGGGTAIAAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12772-1", "uniprot_id": "SRBP2_HUMAN", "id": "Q12772-1", "name": "Sterol regulatory element-binding protein 2", "aln": "------MDDSGELGGLETMETLTELGDELTLGDIDEMLQFVSNQVGEFPDLFSEQLCSSFPGSGGSGSSSGSSGSSSSSSNGRGSSSGAVDPSVQRSFTQVTLPSFSPSAASPQAPTLQVKVSPTSVPTTPRATPILQPRPQPQPQPQ------------TQLQQQTVMITPTFSTTPQTRIIQQPLIY-QNAATSFQVLQPQVQSLVTSSQVQPVTIQQQVQTVQAQRVLTQTANGTLQTLAPATVQTVAAPQVQQVPVLV-QPQIIKTDSLVLTTLKTDGSPVMAAVQNP-ALTALTTPIQTAALQVPTLVGSSGTILTTMPVMMGQ-EKVPIKQVPGG-----------VKQLEPP------KEGERRTTHNIIEKRYRSSINDKIIELKDLVMGTDAKMHKSG-----VLRKAIDYIKYLQQVNHKLRQENMVLKLANQKNKLLKGIDLGSL------VDNEVDLKIEDFNQNVLLMSPPASDSGSQ--AGFSPYSIDSEPGSPLLDDAKVKDEP------DSPPVALGMVDRSRILLCVLTFLCLSFNPLTSLLQWGGAHDSDQHPHSGSGRSVLSFESGS---GGWFDWMMPTLLLWLVNGVIVLSVFVKLLVHGEPVIRPHSRSSVTFWRHRKQADLDLARGDFAAAAGNLQTCLAVLGRALPTSRLDLACSLSWNVIRYSLQKLRLVRWLLKKVFQCRRATPATEAGFEDEAKTSARDAALAYHRLHQLHITGKLPAGSACSDVHMALCAVNLAECAEEKIPPSTLVEIHLTAAMGLKTRCGGKLGFLAS-YFLSRAQSL-CGPEHSAVPDSLRWLCHPLGQKFFMERSWS---VKSAAKESLYCAQRNPADPIAQVHQAFCKNLLERAIESLVKPQAKKKAGDQEEESCEFSSALEYLKLLHSFVDSVGVMSPPLSRSSVLKSALGPDIICRWWTSAITVAISWLQGDDAAVRSHFTKVERIPKALEVTES----PLVKAIFHACRAMHASLPG-KADGQQSSFC--HCERASGHLWSSLNVSGATSDPALNHVVQLLTCDLLLSLRTALWQKQASASQAVGETYHASGAELAGFQRDLGSLRRLAHSFRPAYRKVFLHEATVRLMAGASPTRTHQLLEHSLRRRTT------QSTKHGEVDAWPGQRERATAILLACRHLPLSFLSSPGQRAVLLAEAARTLEKVGDRRSCNDCQQMIVKLGGGTAIAAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KNA7-1", "uniprot_id": "SRBP2_DANRE", "id": "A3KNA7-1", "name": "Sterol regulatory element-binding protein 2", "aln": "------MDASEFMDTMD--PSLSELGDEFTLGDIDEMLQFVSNQV-DFPDIFEDQMGG------------G--------ATARTLPQAVPSAILTPPHTPVQTSSQTHTQTLTQAHTQTHTQT----HTQTRTPPVLQPRPQPITQVQTQTFPMQTLAVQTQAQPQTVMITP---TATPSRFIQNQVICQQNNATSFQVLQPQMQSIMTSPQVQPMTIQH-------QRVLTPAG-QTIQTLS--TAPTTVHTMSQQVPVLVHQPQILKTDSLLLTT-KPDGTQVLSTVQSPTGITTLTTPIQTTALQMPTLMSSN--ILTTVPVVMGGGDKLPIKQLSSGPAHNIGGARVGVEQSPVVGPGGVVKEGERRTTHNIIEKRYRSSINDKILELRDLVLGNDAKMHKSG-----VLRKAIDYIKYLQQVNHKLRQENLTLKMANQKNK--------SA------CVSDVDLELK---AEVSLISPPPSDSGSSSPAQLSPYCIDSEPGSPLLEHEQLKSEP------DSP-SCVGVMDRSRLLLCALSFLCLSLNPLPSLLGAEAPAGSPEVAGHGPTRTLFSLPAQTQSFGAWLWCVLPFLLVWVVSGVGVVWGCVRVLYLWEPVTPLHSPTSVRFWRHRKQADLQLYRGDYAGAVLSLQTCLSVLSRVLPVTTLDIMCSLSWNLIRYCLRRPAPLGWLVRLVGGRHEG---------EESQTSSRDAALVYHKLSQLQLTGQMER-RPLWGVCVSLSAVNLCESAEGKLTATQQVQVYVTAAISVRAALGKHLTCLPA-YLLSCAEALTCQSDSKPLPDCLRWIFTPLGRQFFLSCDWS---VRSESDGQIFTSARDKADPIAQLHRCFCQKLLERATHTLIEPQSREDAG-------EFTGVLEFLQLLNSCTEDSAPSTAPFPALANQSSTSVRDPVCRWWASVLTAAVHWLQGDDASVRSLLAEAERMPRALHTLDH----PLPKAVLALCKAVQMSVCPQKGEGVVSCLS--HCQRASAQLH--ISVCQSHNNTWLHKGVELLVCDLLLTLRTSLWQRGGGSN---GEPGPAPGSQLSGFQRDLSSLRRLGQAHRQAQHKLFLHETTVRLMAGASPTRTHQLLRHRTHNYTT------TDG-----ECVLGERERAHAILLACRHLPLPLLTPPGHRARLLAEAKRTLERVGDRRSLQDCQHILLRLSGGTTIAAS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q61069-1", "uniprot_id": "USF1_MOUSE", "id": "Q61069-1", "name": "Upstream stimulatory factor 1", "aln": "-------------------------------------------------------------------------------MKGQQKTAETEEGTVQIQEGAVATGEDPTSVAIASIQSAATFP-------DPNVKYVFRTE--------------------------------------------------NGGQVMYRVIQVSEGQLDGQTEGS--------------------GAISGYPATQSMTQAVIQGAFTSDDAVDTEGAAAETHYTYFPSTAVGDGSGGTTSGSTTAVVTTQGSEALLGQATPPSTGQFFVMMSPQEVLQGGSQRSIAPRTHPYS----------PKSEAPR----TTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKACDYIQELRQSNHRLSEELQGLDQLQLDNDVLR-------------------QQVEDLKNKNLLLRAQLRHHGLE---------------------VVIKNDS------N----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22415-1", "uniprot_id": "USF1_HUMAN", "id": "P22415-1", "name": "Upstream stimulatory factor 1", "aln": "-------------------------------------------------------------------------------MKGQQKTAETEEGTVQIQEGAVATGEDPTSVAIASIQSAATFP-------DPNVKYVFRTE--------------------------------------------------NGGQVMYRVIQVSEGQLDGQTEGT--------------------GAISGYPATQSMTQAVIQGAFTSDDAVDTEGTAAETHYTYFPSTAVGDGAGGTTSGSTAAVVTTQGSEALLGQATPPGTGQFFVMMSPQEVLQGGSQRSIAPRTHPYS----------PKSEAPR----TTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKACDYIQELRQSNHRLSEELQGLDQLQLDNDVLR-------------------QQVEDLKNKNLLLRAQLRHHGLE---------------------VVIKNDS------N----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B4D0-1", "uniprot_id": "A0A8M2B4D0_DANRE", "id": "A0A8M2B4D0-1", "name": "Upstream stimulatory factor 1", "aln": "-------------------------------------------------------------------------------MKGQPKSSEPDVSVPVIEEGAVATAEDPS--AITTIQSASTFST------DQPIKYLFKTEG-------------------------------------------------AGGQVTYRVIQVADGQLEAQPDGT--------------------TAVSVVTGFPATTQPVTQAVFSQSEGLE--GDGTETHYTYYPAT-ISDATAG------TMVTGVQASDALLSQS--ASAGQLYVMMSPQEVLTGANQRSIAPRTQAYN----------AKSEGPR----TSRDEKRRAQHNEVERRRRDKINNWIVQLSKTIPDCTIDSTKTGQSKGGILSKACDYIQELRQSNSRLGDELNSIERLRMDNQLLR-------------------QEVEDWKSKNQILRNQLRQHGIV---------------------AAASADP------Q----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VW37-1", "uniprot_id": "Q9VW37_DROME", "id": "Q9VW37-1", "name": "", "aln": "MDTTLMNLIDAPLDESMDLFKAEDVFEPFDADLHSDMLDIILNDMDLAPTQMYN------------------------MLLDEPRTHTQQTQSVDQQPQSVEQQPHVKSEHSSPVHIKEELHQ------QQQQSPLLVYKPDPLIATS------------------------------YNCPQQQPTGLLKAAQPTATIHHMDAQRMPPNTAVYPPSLG--------SSFVYQSMSPPTSPVESANQNVNVMQPVAATPAPASAPLPQQSYPQPFITYNSKAGMTSDEAMYFLLQPTVASPTPSPPVAPPPTSTGSRASKVRVAPLAPSPAAMEVQGKVPIN------------RVQPK------VKEVKRSAHNAIERRYRTSINDKINELKNLVVGEQAKLNKSA-----VLRKSIDKIRDLQRQNHDLKAELQRLQRELMARDGSKVKDLLQLGTRPGRASKKRRESSQTFTTDAGLTPPRSDESDPSLSPMHSDISLPPSPYGGSTASCSSGSSSSNEEPLVVPSSMRGMATHSRLGLCMFMFAILAVNPFKTFLQRGHYDSNDDLGDMSGQRRILSYDVEGEGFAVWQ----QSSWIWLLNFTLMLGCLVKLLVYGD---PQLDAQTDAYCQHRQRADFYFSQGQSSQAYAGYLNCLHMFGLSLPASRLECYLQTTWQFLRFLFHRLWLG-----RVLSRRSGGLFSNAASRKQALASARELALLFNRLNQLQLTGNGSRGDMNG-IMMALFASNMAEVAHNLLTPRETICIHVMTALRMKRSAPKWLQQLFARYYMSRARQECGLTRATEQTQELRWAFTAYGYRYCATHVFTYDLSDSGEQDGFFTRLRNPCDPAAHVIKQYREHLLFKAIQCLVG--AGHKSGGLPTSSVSGEAEQLQQQQHSGTIVSNVLKYTSLLKDTLWADEDERDTNVVWWADVLETAVHWLLGEDTLAEQLYGRIKQMPTQLQQCGENDHLPKALHAVLRAKMILLKNNGNALDKSLKQLVNILCDESSVELQECLTVNRITDAKGIKLLFQLLTCDWLLETRTALWELEHMNMED-DGFYQVPGEVLEKFQTDLNSLRNIVENIPNAQSRIYLYEAVCRLMAGASPCPTQQLLDRSLRSRNAHSSIFCGSKDRRQQNFVGGERERASAMYVACKYLPPALLSSPGERAGMLAEAAKTLEKVGDKRKLKECYQLMKSLGNGIGSVKA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12398-1", "uniprot_id": "HMS1_YEAST", "id": "Q12398-1", "name": "Probable transcription factor HMS1", "aln": "----MPNFQKPFSGSSDGNSVMNDLGNKVAIKVFD--------------------------------------------CRSAQDGSEEQNVNVTTNQMYLMFQSNNYNVPPPNYNTEDLGSQ------GPPTHAYYAPFQHPIHLQP-------------------------------------PVPPVYKNNTYSATDQYSDSSFPNTSGHTPVIDSNYYNDALASIPTTTTGSTTMTTDNGNTIDSEEYIDNMEVFSSEENENIDNVKQTDLKSEKDSSLLSAASIVKKEQLSGFENFLPLSKTESPLVTADEIKSSLNLENIDNADSMSFKLKTSPIR---------KHFHVKPK---RITRVRTGRVSHNIIEKKYRSNINDKIEQLRRTVPTLRVAYKKCN--DLPITSRDLADLDGLEPATKLNKASILTKSIEYICHLERKCLQLSLAN---------QHLSNDTRDSFVHLTEPSQPLSDNS-------------------SSEQVQKQT------RSCQRQRQRQPRQQQPLHNIQYNIPHQNGLMSGTNNSHDMDFNNAGDF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : . . . : : : * ** :*:: * .**: * :* : * : : : *. . . . . . . : . .. ", "identical_positions": 11, "similar_positions": 31, "identity": "0.9%" }, { "cls_id": "homologset.agr.SGD:S000005559", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K4W8-1", "uniprot_id": "A0A0G2K4W8_RAT", "id": "A0A0G2K4W8-1", "name": "Exonuclease 1", "aln": "MGIQGLLQFIKEASEPVNVKKYKGQAVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCMKFVNMLLSYGVKPILVFDGCTLPSKKEVERSRRERRQSNLLKGKQLLREGKVSEARECFTRSVNITHAMAHKVIKAARALGVDCLVAPYEADAQLAYLNKAGIVQAVITEDSDLLAFGCKKVILKMDQFGNGLEVDQARLG-MCK-QLGDVFTEEKFRYMCILSGCDYLASLRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMN-ITVPEDYITGFIRANNTFLYQLVFDPIQRKLIPLNAYGDDVNPETLT-YAGQYVNDS-VALQIALGNRDINTFEQIDDYS---PDT-MPAHSRSHSWNDKACQKSPVASSIWHKNYCPRLEVNSVSHAPQLKEKPSTVGLKQVISTKGLNLPRKPCVLKRPR-NEALSEDDLLSQYS-SLTKKIRENSCGNGTSPNSSEMSVPCPDGGTAHKTDAHTPSRTRNKFATFLQRRNEECGAIVVPGTKSRFFCSSPDFDNFIPKKGSNQPPNETVATGKATTSLLGALDCPDTGGQKPVVTNGTHS-----PNTHIPGD-----ATGSPKDEAQSSETSKFLGTMSPPTLGTLRSCFSWSGTLGEFSRTPSPSTRSTLQQFRRKSEPPACLPEACAVT-DVCDSKSGTLGDKSQSLHELDWSSRSQESIDSTCS-LNTSSLSQPSSKDSDSEESDCNNKSLDNQGSQNSKQHLPHFPK-----KDILGRNKVPGLCRSSSMDSLSATKIKPLVPARVSGLSKKPGSIQKRKHHDAENKPGLQIKISELWKNFGFKKDSEKLPSCKK--PLSPVKDNIQLTP-ETEDEIFNKPECARAQRAIFH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ11-1", "uniprot_id": "EXO1_MOUSE", "id": "Q9QZ11-1", "name": "Exonuclease 1", "aln": "MGIQGLLQFIQEASEPVNVKKYKGQAVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCMKFVNMLLSYGVKPILIFDGCTLPSKKEVERSRRERRQSNLLKGKQLLREGKVSEARDCFARSINITHAMAHKVIKAARALGVDCLVAPYEADAQLAYLNKAGIVQAVITEDSDLLAFGCKKVILKMDQFGNGLEVDQARLG-MCK-QLGDVFTEEKFRYMCILSGCDYLASLRGIGLAKACKVLRLANNPDIVKVIKKIGHYLRMN-ITVPEDYITGFIRANNTFLYQLVFDPIQRKLVPLNAYGDDVNPETLT-YAGQYVGDS-VALQIALGNRDVNTFEQIDDYS---PDT-MPAHSRSHSWNEKAGQKPPGTNSIWHKNYCPRLEVNSVSHAPQLKEKPSTLGLKQVISTKGLNLPRKSCVLKRPR-NEALAEDDLLSQYS-SVSKKIKENGCGDGTSPNSSKMSKSCPDSGTAHKTDAHTPSKMRNKFATFLQRRNEESGAVVVPGTRSRFFCSSQDFDNFIPKKESGQPLNETVATGKATTSLLGALDCPDTEGHKPVDANGTHN-----LSSQIPGN-----AAVSPEDEAQSSETSKLLGAMSPPSLGTLRSCFSWSGTLREFSRTPSPSASTTLQQFRRKSDPPACLPEASAVVTDRCDSKSEMLGETSQPLHELGCSSRSQESMDSSCG-LNTSSLSQPSSRDSGSEESDCNNKSLDNQGEQNSKQHLPHFSK-----KDGLRRNKVPGLCRSSSMDSFSTTKIKPLVPARVSGLSKKSGSMQTRKHHDVENKPGLQTKISELWKNFGFKKDSEKLPSCKK--PLSPVKDNIQLTP-ETEDEIFNKPECVRAQRAIFH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQ84-1", "uniprot_id": "EXO1_HUMAN", "id": "Q9UQ84-1", "name": "Exonuclease 1", "aln": "MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFTRSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCKKVILKMDQFGNGLEIDQARLG-MCR-QLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMN-ITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNAYEDDVDPETLS-YAGQYVDDS-IALQIALGNKDINTFEQIDDYN---PDTAMPAHSRSHSWDDKTCQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRPR-SAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTRNKFATFLQRKNEESGAVVVPGTRSRFFCSS-DSTDCVSNKVSIQPLDETAVTDKENN--LHESEYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPPTLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSE-ESSDDESHPLREEACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTSKLRLSHFSK-----KDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHNAENKPGLQIKLNELWKNFGFKKDSEKLPPCKK--PLSPVRDNIQLTP-EAEEDIFNKPECGRVQRAIFQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803U7-1", "uniprot_id": "EXO1_DANRE", "id": "Q803U7-1", "name": "Exonuclease 1", "aln": "MGIQGLLQFIKDASEPMHVKKYRGQTVAVDTYCWLHKGAFSCAEKLAKGEPTDQYVSYCMKFVDMLLSFGVKPILVFDGRNLPSKQEVEKSRRERRQANLQKGKQLLREGKITEARECFTRSVNITPSMAHDVIRAARTRGVDCVVAPYEADAQLAFLNKSDIAQAVITEDSDLLAFGCKKVILKMDKQGNGLEIEQCHLG-RCK-SLGNIFTEEKFRYMCILSGCDYLQSLYGIGLGKACKLLRMANNPDILKVIKKMGQYLKMD-ISVPEEYIEGFTKANNTFLYQLVFDPLRRKVVPLNPYPDHINPAALS-YAGTNVGDE-KGLQMALGNLDINTMQRIDDFNPDAPQTQPPKAPRSSSWNDRCDKTATTQASIWSQNYEPGCTKSQSPTSP--KRPPPTRGKERIVSVQSLKLPQRESQVKRPREDTSLSVDDLLEQYTAGVKRHCPETQPTTKPLTNDNKVSKENHCGSTSG------PFRPRNRFATLLQWRNRSEEGTEEQGTCSRFFCHD-ESNIAETQEDSKQDSSQSVES--------QEKHVSQSGGDTSSLCEEPER---------------------EQDKDEPSSPPASPSCSSRPASVG--LGVFSWSGTTKELNKSVSHPARDSTERQR-SSSTPSGLSTLQQFHRNKARISWAGPG-LSLSSSPVEGSEDAGNSPGSPPS-QDSAYFSQSSSISASVENSLVTEDNSDKEKERDSVVSNSPSSSPLDRLKPAVNRTKVSGLSRKGACGQGKGGKIETSAPARASGLRRKPS---GKKNVNNENSPGLQATISGLWGAFSFKKDSPKLSATKKGEPMSPVGENVVMETTQADKEIFIIAE----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24558-1", "uniprot_id": "EXO1_DROME", "id": "Q24558-1", "name": "Exonuclease 1", "aln": "MGITGLIPFVGKASSQLHLKDIRGSTVAVDTYCWLHKGVFGCAEKLARGEDTDVYIQYCLKYVNMLLSYDIKPILVFDGQHLPAKALTEKRRRDSRKQSKERAAELLRLGRIEEARSHMRRCVDVTHDMALRLIRECRSRNVDCIVAPYEADAQMAWLNRADVAQYIITEDSDLTLFGAKNIIFKLDLNGSGLLVEAEKLH-LAMGCTEEKYHFDKFRRMCILSGCDYLDSLPGIGLAKACKFILKTEQEDMRIALKKIPSYLNMRNLEVDDDYIENFMKAEATFRHMFIYNPLERRMQRLCALEDYETDERYCSNAGTLLEDSEQALHLALGNLNPFSMKRLDSWT------------PEKAWPTPKNVKRSKHKSIWQTNFQSENTHTPK------KENPCALFFKKVDFVG--KTLNEEIEANQRLEQAKQTEAELFNMYSFKAKRRRSPSREDSVDQERTPPPSPVHKSR--------------HNPFAKERTGEEANQRSPVVCENASLLRLLSPKKASPLDGEAGVKKVDSLKRSIFAKEQVQIRSRFFATQDEQTRLQREHLR-----------------------DTENDDMDEQKLSSHSG----------------HKKLRLVCKDIPGKNPIRQRCSSQISDGETDTDTTASSLLESQDKGVPSPLESQEDLNNSQPQIPTEGNTNS-----TTIRIKSLDLLLENSPEPTQESDRNNNDAIILLSDDSCS--------------SDQRASSTSSSSQQRQNFLPTSKRRVGLSKPSTAKKGTPKSRTNGKLGAVSQNQTKLSMFGFQTKPVLK------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39875-1", "uniprot_id": "EXO1_YEAST", "id": "P39875-1", "name": "Exodeoxyribonuclease 1", "aln": "MGIQGLLPQLKPIQNPVSLRRYEGEVLAIDGYAWLHRAACSCAYELAMGKPTDKYLQFFIKRFSLLKTFKVEPYLVFDGDAIPVKKSTESKRRDKRKENKAIAERLWACGEKKNAMDYFQKCVDITPEMAKCIICYCKLNGIRYIVAPFEADSQMVYLEQKNIVQGIISEDSDLLVFGCRRLITKLNDYGECLEICRDNFIKLPKKFPLGSLTNEEIITMVCLSGCDYTNGIPKVGLITAMKLVRRFN-----TIERIILSIQREGKLMIPDTYINEYEAAVLAFQFQRVFCPIRKKIVSLNEIPLYLKDTESK--RKRLYACIGFVIHRETQKKQIVHFDDDIDHH------------LHLKIAQGDLNPYDFHQPLANREHKLQLASKSNIEFG---KTNTTNSEAKVKPIESFFQKMTKLDHNPKVANNIHSLRQAEDKLTMAIKRRKLSNANVVQETLKDTR--------------------------SKFFNKPSMTVVENFKEKGDSIQDFKEDTNSQSLEEPVSESQLSTQIPSSFITTNLEDDDNLSEEVSEVVSDIEEDRK-----------------------NSEGKTIG--------------------------NEIYNTDDDGDGDTSEDYSETAESRVPTSSTTSFPGSSQRSISGCTKVLQKFRYSSSFSGVNANRQPLFPR------HVNQKSRGMVYVNQNRDDDCDDNDGKNQITQRPSLRKS----------------LIGARSQRIVIDMKSVDERKSFNSSPILHEESKKRDIETTKSSQARPAVRSISLLSQFVYKGK----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** **: : .. : :: .*..:*:* *.***:.. .** :** *: ** *: : :* ..:* :. ::* *:*** :* * .* **: *: . . .* *. :* . : :.:::* ** :* .: .: :***:***:*:.:*:: .:.* :*:***** **.:.:* *:: *. * : .: ::: * ****** .: :** .* *.: : : : . : : : ** : * :* . :: *:.::: * :: : : :. . .: :. . : :: : . : : . : .:: . :. . * . . . . : .. . : .: . .:. . . * . .* . :. . * : . . : : . . ... * :: . ", "identical_positions": 83, "similar_positions": 164, "identity": "9.57%" }, { "cls_id": "homologset.agr.SGD:S000005560", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PU37-1", "uniprot_id": "E9PU37_RAT", "id": "E9PU37-1", "name": "Palmitoyltransferase", "aln": "---MEGPG------LGSQCR----NHSHGS-HVPG---FG------QHGICAHENKELAKAKEILPLIEDSSNCDIVKATQYGIFERCKELVEAG-YDVRQPDRENVSLLHWAAINNRLELVKFYISKGAVIDQLGGDLNSTPLHWAIRQGHLPMVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLIS------KGQSVNMTDVNGQTPLMLSAYKVIGPEPTGFLLKFNPSLSAVDKTHQNTPLHWAVAAGNVSAVD-KLLEAGSSLDLRNAKGETPLDMAVQN-KNQLIVHMLRTEAKMRANKKF----RLWQWLHKCELFLLLVLS---MISLWAVGYILNFNSDSWLLKGCLLVALLFLTSLFPRFLVG-YKNLVYLPTVFLLSSIFWIFMTWFILFFPDAAGSP-------FYFAFIFSIMAFLYFFYKTWATDPGFTKASEEER--KVNIVTLAETG--SLDFRTFCTSCLIRKPLRSLHCHVCNSCVARFDQHCFWTGRCIGFGNHHHYIFFLLSLSMVCDWIIYGSFVYWS--NHCATTFKEDGLWTYLNQIVACS-----PWVLYIFMLAAFHFSWSTFLLINQLFQIA-------------------FLGLTSHERISLLKQSRHMKQTLSLRKTPYN----------------------------LGFMQNLADFFQCG--------------CFGLVKPCIID--------------------WTSQYTMVFHPAKEKVLRSV-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWU2-1", "uniprot_id": "ZDH13_MOUSE", "id": "Q9CWU2-1", "name": "Palmitoyltransferase ZDHHC13", "aln": "---MEGPG------LGSQCR----NHSHGS-HVPG---FG------RHGICVHENKELAKAKEILPLIEDSSNCDIVKATQYGIFERCKELVEAG-YDVRQPDRENVSLLHWAAINNRLELVKFYISKGAVIDQLGGDLNSTPLHWAIRQGHLPMVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLIS------KGQSVNMTDVNGQTPLMLSAYKVIGPEPTGFLLKFNPSLSVVDKTHQNTPLHWAVAAGNVSAVD-KLLEAGSSLDIRNAKGETPLDMALQS-KNQLISHMLRTEAKMRANKQF----RLWRWLHKCELFLLLILS---MITLWAVGYILDFNSDSWLLKGCLLVALFFLTSLFPRFLVG-YKNLVYLPTVFLLSSIFWIFMTWFILFFPDTAGSP-------LYFAFIFSIMAFLYFFYKTWATDPGFTKASEEER--KVNIVTLAETG--SLDFRTFCTSCLIRKPLRSLHCHVCNSCVARFDQHCFWTGRCIGFGNHHHYIFFLLSLSMVCDWIIYGSFVYWS--NHCATTFKEDGLWTYLNQIVACS-----PWVLYIFMLAAFHFSWSTFLLINQLFQIA-------------------FLGLTSHERISLLKQSRHMKQTLSLRKTPYN----------------------------LGFTQNLADFFQCG--------------CFGLVKPCIID--------------------WTSQYTMVFHPAKEKVLRSV-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IUH4-1", "uniprot_id": "ZDH13_HUMAN", "id": "Q8IUH4-1", "name": "Palmitoyltransferase ZDHHC13", "aln": "---MEGPG------LGSQCR----NHSHGP-HPPG---FG------RYGICAHENKELANAREALPLIEDSSNCDIVKATQYGIFERCKELVEAG-YDVRQPDKENVSLLHWAAINNRLDLVKFYISKGAVVDQLGGDLNSTPLHWAIRQGHLPMVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLIS------KGQSVNMTDVNGQTPLMLSAHKVIGPEPTGFLLKFNPSLNVVDKIHQNTPLHWAVAAGNVNAVD-KLLEAGSSLDIQNVKGETPLDMALQN-KNQLIIHMLKTEAKMRANQKF----RLWRWLQKCELFLLLMLS---VITMWAIGYILDFNSDSWLLKGCLLVTLFFLTSLFPRFLVG-YKNLVYLPTAFLLSSVFWIFMTWFILFFPDLAGAP-------FYFSFIFSIVAFLYFFYKTWATDPGFTKASEEEK--KVNIITLAETG--SLDFRTFCTSCLIRKPLRSLHCHVCNCCVARYDQHCLWTGRCIGFGNHHYYIFFLFFLSMVCGWIIYGSFIYLS--SHCATTFKEDGLWTYLNQIVACS-----PWVLYILMLATFHFSWSTFLLLNQLFQIA-------------------FLGLTSHERISLQKQSKHMKQTLSLRKTPYN----------------------------LGFMQNLADFFQCG--------------CFGLVKPCVVD--------------------WTSQYTMVFHPAREKVLRSV-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IQZ2-1", "uniprot_id": "ZDH13_DANRE", "id": "A0A0R4IQZ2-1", "name": "Putative palmitoyltransferase ZDHHC13", "aln": "MDWSEGDGSHSHGHMGDSCHGHGGGHSHGHGHSHGGSGFGGFMPAGFHGQLVPGPMDPTQQPRKSSHPEDSSSWDIIKATQFGALERCKELVEAG-YDVRQPDKENVTLLHWAAINNRADIVKYYISKGAVIDQLGGDLNSTPLHWAIRQGHLSMVIQLMRYGADPSLADGEGYRGLHLAVLFQNMPIAAYLMA------KGQEVDLPDLNGQTPLMLAAQKIIGPEPTNFLIKCNASVNAVDKVNRNSPLHCAVLAGNVDSVH-ILLEAGASVDMQNDNGHTAIDLAQQV-HSPLLIHMLSVVKTERIKANS----ACLKLLNRYKVCLQSVFS---VVVVGAFGAILDMRTESWLLKGILLACIMAVINLASRQLAT-VAVRSLIPSTGLIASVFWMVVTWVLWFLPDEPSAA-------VQMLFTVNITAVLYYYIRSCRTDPGHVKATEEEK--KKNIVVLAEAG--CLDPRIFCTSCMMRKPMRANHCFSCNACVAKQDHHSIWINGCIGARNHPFFVLFLVALNFLCIWMFYGSITYWS--RHCPLHYSEEGIWGALTALMGCS-----PWLLYVFCFVFFHTTWASILLVLQLYQIA-------------------FLGLTTSERANLMHRQRKLPQAVSLRQNPFN----------------------------HGVVKNLVNFFQWR--------------FCGLCKPMVLD--------------------WTQQHPMGLGRDMFSSPDAV-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q80TN5-1", "uniprot_id": "ZDH17_MOUSE", "id": "Q80TN5-1", "name": "Palmitoyltransferase ZDHHC17", "aln": "MQREEGFN----TKMADGPD----EYETETGCVPL---LHP----EEIKPQSHYNHGYGEPLGRKTHIDDYSTWDIVKATQYGIYERCRELVEAG-YDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIA------KGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVIS-LLLEAGGNVDAQNVKGESALDLAKQR-KNVWMINHLQEARQAKGYDNP----SFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLDIDSWLIKGLMYGGVWATVQFLSKSFFD-HSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFLF-------IHLPFLANSVALFYNFGKSWKSDPGIIKATEEQK--KKTIVELAETG--SLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCVSYWG--LHCETTYTKDGFWTYITQIATCS-----PWMFWMFLNSVFHFLWVAVLLMCQLYQIT-------------------CLGITTNERMNAR-RYKHFKVTTTSIESPFN----------------------------HGCVRNIIDFFEFR--------------CCGLFRPVIVD--------------------WTRQYTIEYDQISGSGYQLV-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PTT0-1", "uniprot_id": "ZDH17_RAT", "id": "E9PTT0-1", "name": "Palmitoyltransferase ZDHHC17", "aln": "--------------MADGPD----EYDTETGCVPL---LHP----EEIKPQSHYNHGYGEPLGRKTHVDDYSTWDIVKATQYGIYERCRELVEAG-YDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIA------KGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVIS-LLLEAGGNVDAQNVKGESALDLAKQR-KNVWMINHLQEARQAKGYDNP----SFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFD-HSMHSALPLGIYLATKFWMYVTWFFWFWNDLSFLS-------IHLPFLANSVALFYNFGKSWKSDPGIIKATEEQK--KKTIVELAETG--SLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCVSYWG--LHCETTYTKDGFWTYITQIATCS-----PWMFWMFLNSVFHFMWVAVLLMCQMYQIT-------------------CLGITTNERMNAR-RYKHFKVTTTSIESPFN----------------------------HGCVRNIIDFFEFR--------------CCGLFRPVIVD--------------------WTRQYTIEYDQISGSGYQLV-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IUH5-1", "uniprot_id": "ZDH17_HUMAN", "id": "Q8IUH5-1", "name": "Palmitoyltransferase ZDHHC17", "aln": "MQREEGFN----TKMADGPD----EYDTEAGCVPL---LHP----EEIKPQSHYNHGYGEPLGRKTHIDDYSTWDIVKATQYGIYERCRELVEAG-YDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIA------KGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVIS-LLLEAGANVDAQNIKGESALDLAKQR-KNVWMINHLQEARQAKGYDNP----SFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFD-HSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFLF-------IHLPFLANSVALFYNFGKSWKSDPGIIKATEEQK--KKTIVELAETG--SLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCISYWG--LHCETTYTKDGFWTYITQIATCS-----PWMFWMFLNSVFHFMWVAVLLMCQMYQIS-------------------CLGITTNERMNAR-RYKHFKVTTTSIESPFN----------------------------HGCVRNIIDFFEFR--------------CCGLFRPVIVD--------------------WTRQYTIEYDQISGSGYQLV-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5WVX9-1", "uniprot_id": "ZDH17_DANRE", "id": "A5WVX9-1", "name": "Palmitoyltransferase ZDHHC17", "aln": "--------------MADALV----GYEKEAGCVPI---LHP----EEIKPQSHYNHGYNE--SRKSHVDDYSTWDIVKATQYGIFERCRELVEAG-YDVRQPDKENVTLLHWAAINNRVDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCVHLAAQFGHTSIVAYLIA------KGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVIS-LLLEANANVDAQNIKGETPLDLAKQR-KNVWMINHLQEARQAKGYDSP----SYLKRLKMDKEFRQKVMLGTPFLVIWLVGFIADLDIDSWLIKGVMYAVMWLVVQFLSKSFFD-HSMHSALPLGIYLATKFWMYITWFYWFWNDLPFVT-------IHLPFLLNSLALFYNFGKSWKSDPGIIKASEEQK--KKTIVELAETG--SLDLSIFCSTCLIRKPIRSKHCAVCNRCIAKFDHHCPWVGNCVGSGNHRYFMGYLFFLLCMICWMMYGCICYWR--IHCATSYTKDGFWIYITQIATCS-----PWMFWMFLNSVFHFMWVAVLIMCQLYQIA-------------------VLGITTNERMNAR-RYKHFKVTATSIESPFN----------------------------HGCMRNLIDFFELR--------------CCGLLRPVPID--------------------WTSQYTIEYDQTSGSGYQLV-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUW9-1", "uniprot_id": "HIP14_DROME", "id": "Q9VUW9-1", "name": "Palmitoyltransferase Hip14", "aln": "-------------MYQSACQ-----AATTGSCVPG---------TGQQPDNERQSALIAQQPPTAPVEPDYSGFDIVKATQYGAIARVRELVESG-WDVNQPDSETVTLLHWAAINNRRDIIRYFLEKGATVDAVGGELNATPLHWATRQGHLGAVVLLMAAGADPRIRDAEGCSCIHIAAQFAHTALVAYFIA------KGVDPDLQDRGGMTALMWAAWKVCALDPVRLLLTLGANPAMVDYTHGNTALHWAILARNATAISTLVLKSKASLDVPNLRGETPLSMLESQ-TGAIWIGAKVMDRVKEAALTSQQRRSLLSKLRHDKRLRWWSMVACPFTAFYLAGIVFTVNT-LYIIKFFLLGCLYSIFHTIGKALFD-EHLMALLPLSVYLATKAWFYVTWLMYID-DAVSFT-------ATVCFLISSLLLWVCFLKSWKGDPGIIRPTREQR--FKTIIELSERGGIGFEPASFCSGCLVRRPIRSKHCSVCDRCVARFDHHCPWVGNCIGLKNHSYFMGFLWMLLIMCAWMLYGGSKYYV--NQCNVRF--DDFLGAMRAIGNCD-----AWVGWVMGNALLHMSWVILLTICQTYQVI-------------------CLGMTTNERMNRG-RYRHFQAKGG--HSPFT----------------------------RGPIQNLVDFLECS--------------CFGLVQPKRVD--------------------WMNYYDYDAQTHQTIEKEPLLSVDCPDGMAGDHQYV---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12013-1", "uniprot_id": "AKR2_YEAST", "id": "Q12013-1", "name": "Probable palmitoyltransferase AKR2", "aln": "-----------MTSMSIIDDENVKKTSNGAAVVTD-----------VAQHAVSDSDNNKAQLLGDGSNTEYVVDIFIEAAKDGDLKVVKDVVESGAVDINNDRIDELSGLHWACINNRFSVAKFLLLRGANPNQAAGPGGATALHWAARYGNIYIVDLLLKHGADPTLKDEQGLNIMHFSVYSSNILLVVYVLYFVVNNNDNVDIDSKDNNNRTPLLWAAYQGDFLT-VELLLKFGSTVAWTDNRGFN-ALHCALVGGDQRVICDLILSG-ANFYERNNQKQDCFDLAEGMGTKSLFEQALQHHGYDRLGNQK----DKLFKKSSHAQFTIFLSPFLLMVYIYLISLVLSPVLAIMLSLLVTVVMVNTLKKFVLPCLPRKNTYKVSLTRTPFFSGLFLSTFCFLIYIWTKKLYPYSVSDYTMKNVQFLVTSFLTVVLFLRLVRSDPGCLKTDDSLTSIQETIKQLIDLG--KFDRENFCVETLERKPLRSKYSFFSGALVARYDHYCPWIYNDVGLKNHKLFVFFAVTVQYHMFLFMWLCLAYFKKTNYIYEQVEEYARCALLKNETLCKGSNYDPSTFFLFIWISVNFIWLGAMLIVQFFQILKGITTPELFILIKEEHKAKFINLIPFENSIYTSESKGVEDSDMIPEGPSATTITHTISIDGLEPRNRRRAILSACFSMMGINQWLVTIKEIVGITHILHGQVPQQHHSSLLRSFLVTNHWKTNLTDFWLNSDVTAPLWQRFFYSSDTSKAMLGGTEVDYYELYEYPAREGEVLRPN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::*:: * :::**:* *:.: : :: ****.**** .: :: : :** : .* .:*.**** * *:: * *: **** : * :* :*::. : : .*.: .. . : * .. *.*: :* : . :*:. . . * * .** *: . : : :*.. ... * . . :.: . . . . : : : : :. :: . :. : . . * . : : *** :. . .* * : * :: ** : *:*:*: :. .. :*: *::. * :* ** :: : : ::: * : *. . ::: .: * : : * :*: :.: . *. . : . . * * : : : : .* :. : * . : ", "identical_positions": 74, "similar_positions": 154, "identity": "9.49%" }, { "cls_id": "homologset.agr.SGD:S000005561", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A8U9-1", "uniprot_id": "D4A8U9_RAT", "id": "D4A8U9-1", "name": "Protein unc-45 homolog B", "aln": "--------------MAEA-EATQLKEEGNQHFQRQDYKAATKSYSQALKLTK--DKALLATLYRNRAACGLKMESYAQAASDASRAIDINSADIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQETLRRLNTSIQEQLRVQFSTDSRVQTMFEILLN-ENSEADKREKAANNLIVLGREEAGAERIFQSNGVALLLQLMDAKR-PELVLAAVRTLSGMCSGHRARATAILHAVRIDRICSLMALENEEMSLAVCSLLQAIIDSLSGEDKREHRGKEEALVLDTKKDLKQITSHLLDMLVSKKVSGQGRDQALNLLNKNVPRKDLSIHDNSRTIYVVDNGLRKVLKVVGQVPDL--PSCLPLTDNTRMLASILINKLYEDLRCDPERDHFRKICEEYITSKFDPQDMDKNVNAIQTVSGILQGPFDLGNQLLGMKGVMEMMVALCGSEREADQLVAVEALIHASTKLSRATFIITNGVTLLKQIYKTTKNEKIKIRTLVGLCKLGSAGGSDYGLRQFAEGSTEKLAKQCRKWLCNTAIDTRTRRWAVEGLAYLTLDADVKDDFVQDIPALQAMFELAKT--SDKTILYSVANTLVNCTNSYDVKEVVPE-LVQLAKFSKQHVPEEHPKDKKDFVDLRVKRLLKAGVIS-ALACMVKADSAILTDQTKELLARVFLALCDNPKDRGTIVAQGGGKALIPLALEGTDVGK---VKAAHGLAKIAAVSNPDIAFPGERVYEVVRPLVSLLDTQRDG-------------LQNYEALLGLTNLSGRSDKLRQKIFKEKA-----LPDIENYMFENHDQLRQAATECMCNMVLN-----KEVQERFLADGNDRLKLVVLLCGEDDHKLQNAAAGALAMLTAAHKKLCLKMTEVTTQWLEILQRLCLH-DQLSVQHRGLVIAYNLLSADAELARKLVETELLEILTVVGKQEPDETRAAVVQTARECLIKCMDYGFIKPVS--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CGY6-1", "uniprot_id": "UN45B_MOUSE", "id": "Q8CGY6-1", "name": "Protein unc-45 homolog B", "aln": "--------------MAEA-EAAQLKEEGNRHFQLQDYKAATKSYSQALKLTK--DKALLATLYRNRAACGLKMESYAQAASDASRAIDINSADIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQETLRRLNTSIQEQLRVQFSTDSRVQTMFEILLN-ENSEADKREKAANNLIVLGREEAGAERIFQSNGVALLLQLMNTQR-PELLLAAVRTLSGMCSGHRARATAILHAVRIDRICSLMALENEEMSLAVCNLLQAIIDSLSGEDKREHRGKEEALVLDTKKDLKQITSHLLDMLVSKKVSGQGRDQALNLLNKNVPRKDLSIHDNSRTIYVVDNGLRKILKVVGQVPDL--PSCLPLTDNTRMLASILINKLYDDLRCDPERDHFRKICEEYITSKFDPQDMDKNVNAIQTVSGILQGPFDLGNQLLGMKGVMEMMVALCGSEREADQLVAVEALIHASTKLSRATFIITNGVTLLKQIYKTTKNEKIKIRTLVGLCKLGSAGGSDYGLRQFAEGSTEKLAKQCRKWLCNTAIDTRTRRWAVEGLAYLTLDADVKDDFVQDIPALQAMFELAKARTSDKTILYSVANTLVNCTNSYDVKEVVPE-LVQLAKFSKQHVPEEHPKDKKDFVDLRVKRLLKAGVIS-ALACMVKADSAILTDQTKELLARVFLALCDNPKDRGTIVAQGGGKALIPLALEGTDVGK---VKAAHGLAKIAAVSNPDIAFPGERVYEVVRPLVSLLDTQRDG-------------LQNYEALLGLTNLSGRSDKLRQKIFKEKA-----LPDIENYMFENHDQLRQAATECMCNMVLN-----KEVQERFLADGNDRLKLVVLLCGEDDHKLQNAAAGALAMLTAAHKKLCLKMTEVTTQWLEILQRLCLH-DQLSVQHRGLVIAHNLLSADAELARKLVESELLEILTVVGKQEPDEKRAAVVQTARECLIKCMDYGFIKPVS--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IWX7-1", "uniprot_id": "UN45B_HUMAN", "id": "Q8IWX7-1", "name": "Protein unc-45 homolog B", "aln": "--------------MAEV-EAVQLKEEGNRHFQLQDYKAATNSYSQALKLTK--DKALLATLYRNRAACGLKTESYVQAASDASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNTSIQEKLRVQFSTDSRVQKMFEILLD-ENSEADKREKAANNLIVLGREEAGAEKIFQNNGVALLLQLLDTKK-PELVLAAVRTLSGMCSGHQARATVILHAVRIDRICSLMAVENEEMSLAVCNLLQAIIDSLSGEDKREHRGKEEALVLDTKKDLKQITSHLLDMLVSKKVSGQGRDQALNLLNKNVPRKDLAIHDNSRTIYVVDNGLRKILKVVGQVPDL--PSCLPLTDNTRMLASILINKLYDDLRCDPERDHFRKICEEYITGKFDPQDMDKNLNAIQTVSGILQGPFDLGNQLLGLKGVMEMMVALCGSERETDQLVAVEALIHASTKLSRATFIITNGVSLLKQIYKTTKNEKIKIRTLVGLCKLGSAGGTDYGLRQFAEGSTEKLAKQCRKWLCNMSIDTRTRRWAVEGLAYLTLDADVKDDFVQDVPALQAMFELAKAGTSDKTILYSVATTLVNCTNSYDVKEVIPE-LVQLAKFSKQHVPEEHPKDKKDFIDMRVKRLLKAGVIS-ALACMVKADSAILTDQTKELLARVFLALCDNPKDRGTIVAQGGGKALIPLALEGTDVGK---VKAAHALAKIAAVSNPDIAFPGERVYEVVRPLVRLLDTQRDG-------------LQNYEALLGLTNLSGRSDKLRQKIFKERA-----LPDIENYMFENHDQLRQAATECMCNMVLH-----KEVQERFLADGNDRLKLVVLLCGEDDDKVQNAAAGALAMLTAAHKKLCLKMTQVTTQWLEILQRLCLH-DQLSVQHRGLVIAYNLLAADAELAKKLVESELLEILTVVGKQEPDEKKAEVVQTARECLIKCMDYGFIKPVS--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DGE9-1", "uniprot_id": "UN45B_DANRE", "id": "Q6DGE9-1", "name": "Protein unc-45 homolog B", "aln": "------------MTMGEIGDSVQLKEEGNKHFQAGEIDQAIDCYTKAIKTCKKEDKKALAVIYRNRSACFLKKENYSNAASDATKAIDVDAADIKALYRRCQAFEKLGKLDMAFKDVQRCATIEPKNKTFLETLRRLGAEIQQKLKTTFSTDSRVQNMFDILFS-DEPDKEKREKAANNLIVLAREDAGAERIFQNNGVPLLMQLIDTGK-PEMILAAIRTLSGMCTGHRARATAIIHSVGISKLCSIMAVDNEEIALATANLFQCVNDSLSGGDKR-NYGKEEALVLDSSKDLKDILLALLEMIASKNVSGHGRDQALNLLTKNVPRQNKKSTDNSKCLFTIDHGLKKILKVCGQVPDL--PDQLPMTENTQLIASVLLSKLYDDLRCDPERDQFRDICDDYIKSKFDPNDMDKNIHAINTLSGILQGPFDLGNVLAGRQGVMEMMVALCGSEREVDQLVAVEALIHASTKTSKASFFISNGVSLLKEMYKKTKNEKIKIRALVGLCKLGSAGGDDYSMRQFAEGSTEKLAKQCRKWLCNPTLDVRTRKWAIEGLAYLTNDADVKDDFAEDEPAMRAMFELTKS--NDKTILYAVACTLVNCTNSYDKKEIIPE-MVQLAKFSKQHVPEQHPKDKKDFIVRRVKRLLKAGVTS-ALAVMVKADNSILTDQTKEMLARVFLALTEDVKDRGIIVAQGGGKALIPLALEGTDKGK---IKASHALAKIAAVSNPEIAFPGERIYEVVRPLVSLLGTDRDG-------------MENFEALRGLTNLAGLNDKLRVKILKEKA-----LPEIENYMFEDHEQIRQAATECMCNLVCC-----KEVQDRYLEDGNDKLKLLVLLCGEDEEKLQRAAAGALAMLTAAQKKLAVKMTKVTEQWLEILQRLCIH-DNPEIQHRGLVTVFNMLDADDQLAKKLVESDMLEILTYVAKLEDNPKKQNAIDAARACLSKAMDNGLIKPFSN-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q99KD5-1", "uniprot_id": "UN45A_MOUSE", "id": "Q99KD5-1", "name": "Protein unc-45 homolog A", "aln": "MTVSGPETPEPRPSDPGASSAEQLRKEGNELFKCGDYEGALTAYTQALSLGA--TPQDQAILHRNRAACHLKLEDYSKAESEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLKRCVSLEPKNKVFQESLRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPKEKGTEKKQKASQNLVVLAREDAGAEKIFRSNGVQLLQRLLDTEE-TDLMLAALRTLVGICSEHQSRTVATLSVLGTRRVVSILGVENQAVSLAACHLLQVIFDALKEGVKKGFRGKEGAIIVDPARELKVLINSLLELLTEVGVSGQGRDNALTLLIKMVPRKSPKDPNNSLTLWVIDQGLKKILEVGGSLQDA--AGELTVTANSRMSASILLSKLFDDLKCDAERENFHRLCENYIRNWFEGHGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESVIALCASEREEEQLVAVEALIHAAGKAKRASFITANGVSLLKDLYKGSERDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWLCNDQIDAGTRRWAVEGLAYLTFDADVKEEFVEDEAALKALFQLSRS--EERSVLFAVGSALVNCTNSYDYEEPDPK-MVELAKYAKQHVPEQHPKDKPSFVRARVKKLLAAGVVS-AMTCMVKTESPVLTNSCRELLSRVFLALVEEVEDRGTVVAQGGGKALLPLALEGTDVGQ---TKAAQALAKLTITSNPEMTFPGERIYEVVRPLVSLLHLSCSG-------------LQNFEALMALTNLAGISERLRQKILKEKA-----VPMIEGYMFEEHEMIRRAATECMCNLAMS-----KEVQDLFEAQGNDRLKLLVLYSGEDDELLRRAAAGGLAMLTSMRPALCSRIPQVTTHWLEILQALLLS-PNQELQHRGTVVVLNMMQSSKEIAGTLMESEVLEILSVLAKGEESP----VTRAAAACLEKAVEYRLIQPNQDGE-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q32PZ3-1", "uniprot_id": "UN45A_RAT", "id": "Q32PZ3-1", "name": "Protein unc-45 homolog A", "aln": "MTVSGPGTPEPRPSDPGASSAEELRKEGNELFKCGDYEGALTAYTQALSLGA--TPQDQAILHRNRAACHLKLEDYSKAESEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLKRCVSLEPKNKVFQESLRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPKEKGTEKKQKASQNLVVLAREDAGAEKIFRSNGVQLLQRLLDTGE-TDLMLAALRTLVGICSEHQSRTVATLSVLGTRRVVSILGVENQAVSLAACHLLQVMFDALKEGVKKGFRGKEGAIIVDPARELKVLISNLLELLTEIGVSGQGRDNALTLLIKMVPRKSPKDPNNSLTLWVIDQGLKKILEVGGSVPEA--AGELTVTANSRMSASILLSKLFDDLKCDAERENFHRLCENYIRSWFEGQGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESVIALCASEQEEEQLVAVEALIHAAGKAKRASFITANGVALLKDLYKGSERDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWLCNDQIDAGTRRWAVEGLAYLTFDADVKEEFVEDEAALKALFQLSRS--EERSVLFAVGSALVNCTNSYDYEEPDPK-MVELAKYAKQHVPEQHPKDKPSFVRARVKKLLAAGVVS-AMTCMVKTESPVLTNSCRELLSRVFLALVEEVEDRGTVVAQGGGKALLPLALEGTDVGQ---TKAAQALAKLTITSNPEMTFPGERIYEVVRPLVSLLHLSCSG-------------LQNFEALMALTNLAGISERLRQKILKEKA-----VPMIEGYMFEEHEMIRRAATECMCNLAMS-----KEVQDLFEAQGNDRLKLLVLYSGEDDELLRRAAAGGLAMLTSMRPSLCSRIPQVTTHWLEILQALLLS-PNPELQHRGTVVVLNMMESSKEIASTLMESEVLEILSVLAKGEESP----VTRAAAACLEKAVEYRLIQPNQDGE-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H3U1-1", "uniprot_id": "UN45A_HUMAN", "id": "Q9H3U1-1", "name": "Protein unc-45 homolog A", "aln": "MTVSGPGTPEPRPATPGASSVEQLRKEGNELFKCGDYGGALAAYTQALGLDA--TPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVVLAREDAGAEKIFRSNGVQLLQRLLDMGE-TDLMLAALRTLVGICSEHQSRTVATLSILGTRRVVSILGVESQAVSLAACHLLQVMFDALKEGVKKGFRGKEGAIIVDPARELKVLISNLLDLLTEVGVSGQGRDNALTLLIKAVPRKSLKDPNNSLTLWVIDQGLKKILEVGGSLQDP--PGELAVTANSRMSASILLSKLFDDLKCDAERENFHRLCENYIKSWFEGQGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESVIALCASEQEEEQLVAVEALIHAAGKAKRASFITANGVSLLKDLYKCSEKDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWLCNDQIDAGTRRWAVEGLAYLTFDADVKEEFVEDAAALKALFQLSRL--EERSVLFAVASALVNCTNSYDYEEPDPK-MVELAKYAKQHVPEQHPKDKPSFVRARVKKLLAAGVVS-AMVCMVKTESPVLTSSCRELLSRVFLALVEEVEDRGTVVAQGGGRALIPLALEGTDVGQ---TKAAQALAKLTITSNPEMTFPGERIYEVVRPLVSLLHLNCSG-------------LQNFEALMALTNLAGISERLRQKILKEKA-----VPMIEGYMFEEHEMIRRAATECMCNLAMS-----KEVQDLFEAQGNDRLKLLVLYSGEDDELLQRAAAGGLAMLTSMRPTLCSRIPQVTTHWLEILQALLLS-SNQELQHRGAVVVLNMVEASREIASTLMESEMMEILSVLAKGDHSP----VTRAAAACLDKAVEYGLIQPNQDGE-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHW4-1", "uniprot_id": "Q9VHW4_DROME", "id": "Q9VHW4-1", "name": "", "aln": "--------MTNTINSEEVSDAGSYKDKGNEAFKASRWEEAVEHYGKAIKAGS--KHKELAVFYKNRAAAYLKLGKYENAVEDCTESLKAAPGDPKALFRRAQAYEALEKFEEAYKDATALFKADPGNKTVQPMLQRLHVVVEERSARNAKTSTKVKQMMDLTFD-LATPIDKRRAAANNLVVLAKEQTGAELLYKDHCIAKVASLTKVEKDQDIYVNMVHLVAALCENSVERTKGVLTELGVPWFMRVLDQKHENCVSTAQFCLQTILNALSGLKNKPDSKPEKELCTRNNREIDTLLTCLVYSITDRTISGAARDGVIELITRNVHYTALEWAER----LVEIRGLCRLLDVCSELEDYKYESAMDITGSSSTIASVCLARIYENMYYDEAKARFTDQIDEYIKDKLLAPDMESKVRVTVAITALLNGPLDVGNQVVAREGILQMILAMATTDDELQQRVSCECLIAASSKKDKAKALCEQGVDILKRLYHS-KNDGIRVRALVGLCKLGSYGGQDAAIRPFGDGAALKLAEACRRFLIKPGKDKDIRRWAADGLAYLTLDAECKEKLIEDKASIHALMDLARG--GNQSCLYGVVTTFVNLCNAYEKQEMLPE-MIELAKFAKQHIPEEHELDDVDFINKRITVLANEGITT-ALCALAKTES----HNSQELIARVLNAVCGLKELRGKVVQEGGVKALLRMALEGTEKGK---RHATQALARIGITINPEVSFSGQRSLDVIRPLLNLLQQDCTA-------------LENFESLMALTNLASMNESVRQRIIKEQG-----VSKIEYYLMEDHLYLTRAAAQCLCNLVMS-----EDVIKMFEGN-NDRVKFLALLCEDEDEETATACAGALAIITSVSVKCCEKILAIAS-WLDILHTLIAN-PSPAVQHRGIVIILNMINAGEEIAKKLFETDIMELLSGLGQLPDDTR-AKAREVATQCLAAAERYRIIERSDNAEIPDVFAENSKISEIIDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P51534-1", "uniprot_id": "SHE4_YEAST", "id": "P51534-1", "name": "SWI5-dependent HO expression protein 4", "aln": "---------------------MPLCEKGNDPIDSSTIDSLCAAFDKTLKSTP-------------------DVQKYNDAINTIFQLRQKSESG------------------KMPADLTNSEALKDRQK------------IEEILTRSYQDHSESRVHLSKLIQ--------------------------------NDIPFALNLFEILS-----RSSIHVFVG-CFSNKDATIALLNELQIR--------IHYGEDTHVTYLLSIILQLLN-------------KFKYNFKEVRFLVKELILRISEDEVKS-----MMLIIFAELQSS--------------------------------------FQKDFDKAVVDFMSSLIVEAEIDVGNDPLSIIVKTLSELYPSLTTLCSEIFLTKGLSKLFKKRVFEEQDLQFTKELLRLLSSACIDET--MRTYITENYLQLLERSLNVEDVQIYSALVLVKTWSFTKLTCINLKQLSEIFINAISRRIMPKIENVNES-AVKLEEVPKVEMS------------VEALAYLSLKASVKIMIRSNESFTEILLTMIKSQ-KMTHCLYGLLVIMANLSTLPEESNGSSQSINDLKNYADLKGPGADKVGAEKESKEDILLFNEKYILRTELISFLKREMHNLSPNCKQQVVRVIYNITRSKNFIPQCISQGGTTIILEYLANKQDIGEPIRILGCRALTRMLIFTNPGLIFKKYSALNAIPFLFELLPRSTPVDDNPLHNDEQIKLTDNYEALLALTNLASSETSDGEEVCKHIVSTKVYWSTIENLMLDENVPLQRSTLELISNMMSHPLTIAAKFFNLENPQSLRNFNILVKLLQLSDVESQRAVAAIFANIATTIPLIAKELLTKKELIENAIQVFADQIDDIELRQRLLMLFFGLFEVIPDNG----TNEVYPLLQENQKLKDALNMSLKRGDSGPEFSAAIPVILAKIKV--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:** :. : ::: . .* .* . . .. * . :: ::: . :. . :. :. : : * . :: . . * : : : . :. : : *. ::: : *: : . :.. : :: : . . . : : : * . : . : :: :: ::: : . ::. : : . : : * : : .. . .. :* : : *.:: * : . :. . :. : ** : : : :.****: .*. * : .: . . :: : : *:.: :.* . : .: .: : :* :::. : * . . . : : : : : * : . :: : **: : : : :** :: : : *: . :.*::: ** : * :.: *. ** . :*:*:* .****:. . .: *. . ** ::::: : ::: : :.*: .. . : ..:::. .: * *. :* ::: . .: : :: : . :::* : .:. : . .:: :* : : : . : : ", "identical_positions": 55, "similar_positions": 245, "identity": "5.49%" }, { "cls_id": "homologset.agr.SGD:S000005562", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7P1-1", "uniprot_id": "STX12_RAT", "id": "G3V7P1-1", "name": "Syntaxin-12", "aln": "------------------------------MSYGPLDMYR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NPGPSGPQPRDFNSIIQTCSGNIQRISQATAQIKNLMSQLGTKQDSSKLQENLQQ-FQHSTNQLAKETNELLKELGSLPLPLSASEQRQQ----KLQKERLMNDFSSALNNFQVVQRKVSEKEKESIARARAGSRLS---AEDRQREEQLVSFDSHEEWNQMQSQEEEAAITEQD-----LELIKERETAIQQLEADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERASDQLQRAAYYQ---------------KKSRKKMCILVLVLSVIVTVLVVVIWVASK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER00-1", "uniprot_id": "STX12_MOUSE", "id": "Q9ER00-1", "name": "Syntaxin-12", "aln": "------------------------------MSYGPLDMYR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NPGPSGPQPRDFNSIIQTCSGNIQRISQATAQIKNLMSQLGTKQDSSKLQENLQQ-LQHSTNQLAKETNELLKELGSLPLPLSASEQRQQ----KLQKERLMNDFSSALNNFQVVQRKVSEKEKESIARARAGSRLS---AEDRQREEQLVSFDSHEEWNQMQSQEEEAAITEQD-----LELIKERETAIRQLEADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATDQLQRAAYYQ---------------KKSRKKMCILVLVLSVIVTVLVVVIWVASK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86Y82-1", "uniprot_id": "STX12_HUMAN", "id": "Q86Y82-1", "name": "Syntaxin-12", "aln": "------------------------------MSYGPLDMYR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NPGPSGPQLRDFSSIIQTCSGNIQRISQATAQIKNLMSQLGTKQDSSKLQENLQQ-LQHSTNQLAKETNELLKELGSLPLPLSTSEQRQQ----RLQKERLMNDFSAALNNFQAVQRRVSEKEKESIARARAGSRLS---AEERQREEQLVSFDSHEEWNQMQSQEDEVAITEQD-----LELIKERETAIRQLEADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATEQLQRAAYYQ---------------KKSRKKMCILVLVLSVIILILGLIIWLVYKTK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5F7-1", "uniprot_id": "A0ACD6B5F7_DANRE", "id": "A0ACD6B5F7-1", "name": "Syntaxin-12", "aln": "MIVCFLSIHFDFCERSSASPPHLSITVTVIMSYGMMDSS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HSQSQPRDFNNLTQTCSSNIQKITQNTGQIKSMLFQLGTRPDTPELQDRLQQ-VQHYTNQLAKETNRHLKDLGTLPQPQSPSEQRQQ----RIQKDRLMNDFSAALNNFQVVQRRAAERERESVARARAGSRFQ---VDELNQDEQLVTFEKNEGW-RMQTEEE--PVTEED-----LELIKERETNIRQLESDIMDVNQIFKDLAVMIHDQGDMIDSIEANVESAEVHVERGAEQLQHAAYYQ---------------RKSRKRMCILALVLSLVATIFAIIIWQAIR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O70439-1", "uniprot_id": "STX7_MOUSE", "id": "O70439-1", "name": "Syntaxin-7", "aln": "------------------------------MSY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPGIGGDSAQLAQRISSNIQKITQCSVEIQRTLNQLGTPQDSPELRQLLQQ-KQQYTNQLAKETDKYIKEFGSLP--TTPSEQRQR----KIQKDRLVAEFTTSLTNFQKAQRQAAEREKEFVARVRASSRVSGGFPEDSSKEKNLVSWES-QTQPQVQVQDE--EITEDD-----LRLIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDMIDSIEANVESAEVHVQQANQQLSRAADYQ---------------RKSRKTLCIIIFILVVRIVIICLIVWGLKG--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70257-1", "uniprot_id": "STX7_RAT", "id": "O70257-1", "name": "Syntaxin-7", "aln": "------------------------------MSY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPGIGGDPAQLAQRISSNIQKITQCSAEIQRTLNQLGTPQDTPELRQQLQQ-EQQYTNQLAKETDKYIKEFGFLP--TTPSEQRQR----KIQKDRLVAEFTTALTNFQKVQRQAAEREKEFVARVRASSRVSGGFPEDSSKEKNFVSWES-QTQPQVQVQDE--EITEDD-----LRLIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDVIDSIEANVESAEVHVQQANQQLSRAANYQ---------------RKSRKTLCIIILILVVGIVIIFFIVWGLKG--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15400-1", "uniprot_id": "STX7_HUMAN", "id": "O15400-1", "name": "Syntaxin-7", "aln": "------------------------------MSY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPGVGGDPAQLAQRISSNIQKITQCSVEIQRTLNQLGTPQDSPELRQQLQQ-KQQYTNQLAKETDKYIKEFGSLP--TTPSEQRQR----KIQKDRLVAEFTTSLTNFQKVQRQAAEREKEFVARVRASSRVSGSFPEDSSKERNLVSWES-QTQPQVQVQDE--EITEDD-----LRLIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDVIDSIEANVENAEVHVQQANQQLSRAADYQ---------------RKSRKTLCIIILILVIGVAIISLIIWGLNH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96NA8-1", "uniprot_id": "TSNA1_HUMAN", "id": "Q96NA8-1", "name": "t-SNARE domain-containing protein 1", "aln": "-------MSYGSIARGGGLGSRGPFGGPSRQGCQPLECARCWTEYGIRHFPCPSPESKLQNRCVGKDGEGDLGPAGTPIVPRARKRGPGVAPEGSRMPEPTSSPTIGPRKDSAAGPHGRMAGPSTTRAKKRKPNFCPQETEVLVSKVSKHHQLLFGTGLLKAEPTRRYRVWSRILQAVNALGYCRRDVVDLKHKWRDLRAVVRRKLGDLRKAAHGPSPGSGKPQALALTPVEQVVAKTFSCQALPSEGFSLEPPRATQVDPCNLQELFQEMSANVFRINSSVTSLERSLQSLGTPSDTQELRDSLHT-AQQETNKTIAASASSVKQMAELLRSSCPQERLQQE---RPQLDRLKTQLSDAIQCYGVVQKKIAEKSRALLPMAQRGSKQSPQ-APFAELADDEKVFNGSDNMWQGQEQALLPDITEED-----LEAIRLREEAILQMESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHAEAARQLLAGASRHQ---------------LQRHKIKCCFLSAGVTALLVIIIIIATSVRK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T5F7-1", "uniprot_id": "A0AB32T5F7_DANRE", "id": "A0AB32T5F7-1", "name": "", "aln": "-------MSYGSIDAG-SFGSRNPFGGPTRQGYQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVATQVSPSELQDVFQETSSNIFQINANVVTLEKNLQSLGTSRDTAELRQSLHS-TQQQTNKVITSTSQLVKQLTDIISGSSRQDRLR--------LTRLKTELSDSVQRYGELQKKIADRSRALLPPAQKDRKQSVQ-TPFSELVEEGPLF-GAGESTEGDVQAFLSEISEED-----VEILRQREEALLQIERDMLDVNQIMKDLASMVHEQGDTIDSIEDYIQTTSSHVETANQELAKASHYQDTGQLTLLEASSNQRRQLRRRKCFLLIGGLLLLTLLIIIIAVSARK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VU45-1", "uniprot_id": "Q9VU45_DROME", "id": "Q9VU45-1", "name": "", "aln": "-------MSKALNNPGGNGGGGGPHRDYGAMADSTPEVSFAAAG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSSGFSPTEFMSLSEDIGHNITAIHSSTKQLEKQLKLIGTSKEQPNLREKVHT-INTKCNARVQTTSQDLQRLQAVVR---HGDRQQK-----LQLEKLTREFHGVVEKYSNLQRRISSAMRQTLQQAQ-------------QFADQVVETNARAELLQQQRLEQ--AHLQQE-----HDMLDDRRRQVEQIESDIIDVNQIMTQLSGLVHDQGQQMDFIENSIEQTAANVEDGTSELAKAARSR---------------QSYRRKILILLVIAVIIGLIVTGVIVAKLNS-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32854-1", "uniprot_id": "PEP12_YEAST", "id": "P32854-1", "name": "Syntaxin PEP12", "aln": "-------MSEDEFFGGDNEAVWN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSRFSDSPEFQTLKEEVAAELFEINGQISTLQQFTATLKSFIDRGDVSAKVVERINKRSVAKIEEIGGLIKKVNTSVKKMDAIEEASLDKTQIIAREKLVRDVSYSFQEFQGIQRQFTQVMKQVNERAKESLEASEMANDAALLDEEQRQNSSKSTRIPGSQIVIERDPINNEEFAYQQNLIEQRDQEISNIERGITELNEVFKDLGSVVQQQGVLVDNIEANIYTTSDNTQLASDELRKAMRYQ---------------KRTSRWRVYLLIVLLVMLLFIFLIMKL-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . :: * :: : : : .: : : :: . :. :* :. . : *:: :. : .: : . ::: : * : ::* .: ::*:::.:*. :: :** :* ** : : :.: . . * * : : : .. :: ", "identical_positions": 14, "similar_positions": 69, "identity": "2.56%" }, { "cls_id": "homologset.agr.SGD:S000005564", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LY86-1", "uniprot_id": "A0ABK0LY86_RAT", "id": "A0ABK0LY86-1", "name": "Protein HIRA", "aln": "MLVLESLEGRTGKRPPSAERGRVFPPFYFVMHLEGATVCVCVCVCVCVCIRARACVKQGKPIFSVDIHPDGTKFATGGQGQDSGKVVIWNMSPVLQEDDEKDENIPKMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWKRATYIGPSTVFGSSGKLANVEQWRCVSILRSHSG-DVMDVAWSPHD-AWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMN----NSGPTAQIIEREG-WKTNMDFVG-HRKAVTVVKFNPKIFKKKQKNGSSAKPSCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQDELGDPLSEEEKSRIHQSTYGKSLAIMTEAQLSTAVIENPEMLKYQRRQQQQQLDQKNATTRETSSASSVTGVVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDFSTAFFNSIPLSSSLAGTMLSSPSGQQLLPLDSSTP-SFGASKPCTEPVAATSARPTG------EPVSKDSMNATSTPAALSPSVLTTPSKIEPMKAFDSRFTERSKATPGAPSLTSVIPTAVERLKEQNLVRELRSRE-LDSSSDSDEKVHLAKPSSLSK-RKLELEVETVEKKKKGRPRKDSRLLPVSLSVQSPAALSAEKEAMCLSAPALALKLPIPGPQRAFTLQVSSDPSMYIEVENEVTTVGGIRLSRLKCNREGKEWETVLSSRVLTAAGSCD----VVCVACEKRMLSVFSTCGRRLLPPILLPSPISTLHCTGPYVMALTAAATLSVWDVHRQVVVVKEES-------LHSILSGSDMTVSQILLTQHGIPVMNLSDGKAYCFNPSLSTWNLVSDKQDSLAQCADFRNSLPSQDAMLCSGPLAIIQGRTS-------------NSGRQAARLFSVPHVVQQESTLAYLESQVAAALTLQSSHEYRHWLLLYARYLVNEGFEYRLREICQDLLGPVHCSTGSQWESTVVGLRKRELLKELLPVIGQNLRFQRLFTECQEQLDILRDK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61666-1", "uniprot_id": "HIRA_MOUSE", "id": "Q61666-1", "name": "Protein HIRA", "aln": "----------------------------------------------MKLLKPTWVNHNGKPIFSVDIHPDGTKFATGGQGQDSGKVVIWNMSPVLQEDDEKDENIPKMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWKRATYIGPSTVFGSSGKLANVEQWRCVSILRSHSG-DVMDVAWSPHD-AWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMN----NSGPTAQIIEREG-WKTNMDFVG-HRKAVTVVKFNPKIFKKKQKNGSSTKPSCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQDELGDPLSEEEKSRIHQSTYGKSLAIMTEAQLSTAVIENPEMLKYQRRQQQQQLDQKNATTRETSSASSVTGVVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDFSTAFFNSIPLSSSLAGTMLSSPSGQQLLPLDSSTP-SFGASKPCTEPVAATSARPTG------ESVSKDSMNATSTPAASSPSVLTTPSKIEPMKAFDSRFTERSKATPGAPSLTSVIPTAVERLKEQNLVKELRSRE-LESSSDSDEKVHLAKPSSLSK-RKLELEVETVEKKKKGRPRKDSRLLPMSLSVQSPAALSTEKEAMCLSAPALALKLPIPGPQRAFTLQVSSDPSMYIEVENEVTTVGGIRLSRLKCNREGKEWETVLSSRVLTAAGSCD----VVCVACEKRMLSVFSTCGRRLLPPILLPSPISTLHCTGPYVMALTAAATLSVWDVHRQVVVVKEES-------LHSILSGSDMTVSQILLTQHGIPVMNLSDGKAYCFNPSLSTWNLVSDKQDSLAQCADFRNSLPSQDAMLCSGPLAIIQGRTS-------------NSGRQAARLFSVPHVVQQETTLAYLENQVAAALTLQSSHEYRHWLLLYARYLVNEGFEYRLREICKDLLGPVHCSTGSQWESTVVGLRKRELLKELLPVIGQNLRFQRLFTECQEQLDILRDK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54198-1", "uniprot_id": "HIRA_HUMAN", "id": "P54198-1", "name": "Protein HIRA", "aln": "----------------------------------------------MKLLKPTWVNHNGKPIFSVDIHPDGTKFATGGQGQDSGKVVIWNMSPVLQEDDEKDENIPKMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWKRATYIGPSTVFGSSGKLANVEQWRCVSILRNHSG-DVMDVAWSPHD-AWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMN----NSGPTAQIIEREG-WKTNMDFVG-HRKAVTVVKFNPKIFKKKQKNGSSAKPSCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQDELGDPLSEEEKSRIHQSTYGKSLAIMTEAQLSTAVIENPEMLKYQRRQQQQQLDQKSAATREMGSATSVAGVVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDFSTAFFNSIPLSGSLAGTMLSSHSSPQLLPLDSSTPNSFGASKPCTEPVVAASARPAG------DSVNKDSMNATSTPAALSPSVLTTPSKIEPMKAFDSRFTERSKATPGAPALTSMTPTAVERLKEQNLVKELRPRDLLESSSDSDEKVPLAKASSLSK-RKLELEVETVEKKKKGRPRKDSRLMPVSLSVQSPAALTAEKEAMCLSAPALALKLPIPSPQRAFTLQVSSDPSMYIEVENEVTVVGGVKLSRLKCNREGKEWETVLTSRILTAAGSCD----VVCVACEKRMLSVFSTCGRRLLSPILLPSPISTLHCTGSYVMALTAAATLSVWDVHRQVVVVKEES-------LHSILAGSDMTVSQILLTQHGIPVMNLSDGKAYCFNPSLSTWNLVSDKQDSLAQCADFRSSLPSQDAMLCSGPLAIIQGRTS-------------NSGRQAARLFSVPHVVQQETTLAYLENQVAAALTLQSSHEYRHWLLVYARYLVNEGFEYRLREICKDLLGPVHYSTGSQWESTVVGLRKRELLKELLPVIGQNLRFQRLFTECQEQLDILRDK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O17468-1", "uniprot_id": "HIRA_DROME", "id": "O17468-1", "name": "Protein HIRA homolog", "aln": "----------------------------------------------MRLLKPAWVHHDDKQIFSVDIHKDCTKFATGGQGSDCGRVVIWNLLPVLSDKAEFDADVPKMLCQMDQHLACVNCVRWSQNGQNLASGSDDKLIMIWRKS--AGSSGVFGTGGMQKNHESWKCFYTLRGHDG-DVLDLAWSPND-VYLASCSIDNTVIIWDAQAFPHSVATLKGHTGLVKGVSWDPLGRFLASQSDDRSIKIWNTMNWSLSHTITEPFEECGGTTHILRLSWSPDGQYLVSAHAMN----GGGPTAQIIEREG-WKCDKDFVG-HRKAVTCVRFHNSILSRQENDGSPSKP-LQYCCLAVGSRDRSLSVWMTALQRPMVVIHELFNASILDLTWGPQECLLMACSVDGSIACLKFTEEELGKAISEEEQNAIIRKMYGK--NYVNGLGKSAPVLEHPQRLLLPQGDKPTKFPLSNNNEANQRPISKQTETRTKDGKRRITPMFIPLHEDGPTSLSMNIVSSSGSSTTALTSCSAAIGTLPAAAPTESAATPLMPLEPLVSKIDLGRLDSRLKTQPASQRRQSLPFDPGQSNELLRTPRLEEHQSSTCSPSNLNVTATGKSEFVKAALDYRLHVSNGHLKTQHGMLAKVTASDSKEMLWEFYVGSPLVNLNLCEKYAMLCSLDGSMRLISMETGCPVFPAISLTSSAVHCAFSPDNSLVGVLTECGLLRIWDIAKKVVSLAAGCLELLN-KHGTAAQFSVTNQGMPLIGFPSGNSYSYSTSLQSWLVLATKDAIMYHGIRGTLPRDMDQMQQKFPLLSMQASSQNYFSFTGSMELRHSESWQQCAKIRFIENQIKLCEALQSLDELQHWHKMLTFQLATHGSEKRMRVFLDDLLSMPEPGISQFVPKLELMQCVLDTLKPHSEWNRLHSEYTELLKECKSERQKDIFATPAPPQQKTASSAGSSPRSGEATGEEVTEKDGATAVAAAVVAGSRMAVTTGTSTTTTTTASSSLSSSGSSSSTSGSGSSSSSSSTSSLSVPQPAPSLSPEIQTLDSPTVCIDDEILSASSSLPPLDTSPVEVSPASTSGGAASTSPAASVAGSAPVSSSKTDQT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32480-1", "uniprot_id": "HIR2_YEAST", "id": "P32480-1", "name": "Protein HIR2", "aln": "----------------------------------------------MRLLKYPLDIHNEQVNALAALGPYIILAGSGG------HVMAWRQQ------QLVDTAFDRVMIKDLKPEVSFQVDQDTTGDIFFITGDLETLYIGSEHRLWGYSGWLCRDTNNINSVEKMNSKLLFECKSPSTITDVKYDINLGILFVLLSNENKILLFRHKTFDKLSEITIDKASKPITGIIDPTGQTFTVMTSDRSILVYQINKTGTHKLINKLTQHVQMYPLHYRISMSPQADILPVINSVKGVPNNATSCTALLDRNNNYKVTKTLVTPSSNGCRVLVYSPAFYEKPNLKKGTSTR--YNLIATSGSTDGTILVWNTKRMKPLFNALQVSSTAINDMSWSQDGFTLFAISNDATLYTFAFQEKDLGVALPQTEIK------------SLQEVNKKLPKLEEP---------LAEQIPKSFPENIKLEESASAAPIPNDIGRSAVGKKPTKKKTANNQTNGIKTIQS---TSMEFNTPSYTVPRDLKRKPKEATPSNIAP-----------------GSKKQKKELQPIDFLDTG------LLLPNTSFSRIRLATPKIRSTFKYSPINNPNLILDVKNGSGNEQRPTIVKLTSKVLDQDQVLFQDFIPKLITICTAGDTFWSFCSEDGSIYIYSDSG---RKLMAPLVLGVSISFLEACGTYLLCLTSIGELYCWNIEQKKLAFPTNTIYPLLNPSLRYSDDILTRAENITLCSITKKGVPLVT-------LSNGDGYLFDKNMETWLLVSDGWWAYG---------------------------------------------------SQYWDTTNTTGLSSSKAN-------TDSFNGSESNINEIVSDIK--------NDNQSIINFLECKTNDELNRKGRIKNLQRFARTILMKEGFEN----------------------------------------MEEIVTLSHLENKILISIRLEEPEEFSKLMMVYCIRLSELGYMDRLNDVFQWLYDDLPISG--TGSAFADKDFKRNLLKKILIACGDIRQVQRVTTRYAKEMNIIS-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :: : . : .:** :*: *. * . ::: : : ...: : : .. : :*. :.* : .: .. : . . *. .. :. :. : *: :. : :. * :*.:::: * . .::. ** *: :: :.***: ::. . *.: :. . *:* **:.. * :::: .. . : :::*:. :* :* :. : : : .: : . ..:. : ** * :: ** * :*:. :: . :* *::* : ::. * *.:: : * :.:** .:.: * . : . . :*.* :: . : :. : . . : : : . . : . : * :. . : . :: .: . : . .: :. . :. : . . : * : : : :. . * . . . : . :: :.:.: : : : : . .. :. :. : . *. : . : . : .: :.::: . * . . .. : * . :: . * : .. . . . . * * : * . .: :: . . . : : ", "identical_positions": 55, "similar_positions": 256, "identity": "4.97%" }, { "cls_id": "homologset.agr.SGD:S000005565", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P67870-1", "uniprot_id": "CSK2B_HUMAN", "id": "P67870-1", "name": "Casein kinase II subunit beta", "aln": "------------------------MSSSEEVS-----WISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDN-PNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKS-PVKTIR--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P67871-1", "uniprot_id": "CSK2B_MOUSE", "id": "P67871-1", "name": "Casein kinase II subunit beta", "aln": "------------------------MSSSEEVS-----WISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDN-PNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKS-PVKTIR--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P67874-1", "uniprot_id": "CSK2B_RAT", "id": "P67874-1", "name": "Casein kinase II subunit beta", "aln": "------------------------MSSSEEVS-----WISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDN-PNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKS-PVKTIR--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91398-1", "uniprot_id": "CSK2B_DANRE", "id": "Q91398-1", "name": "Casein kinase II subunit beta", "aln": "------------------------MSSSEEVS-----WISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDN-PNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASSFKS-PVKAIR--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08182-1", "uniprot_id": "CSK2B_DROME", "id": "P08182-1", "name": "Casein kinase II subunit beta", "aln": "------------------------MSSSEEVS-----WVTWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPNYRQALDMILDLEPEDELEDN-PLQSDMTEQAAEMLYGLIHARYILTNRGIAQMIEKYQTGDFGHCPRVYCESQPMLPLGLSDIPGEAMVKTYCPKCIDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPTNQFVPRLYGFKIHSLAYQIQLQAAANFKM-PLRAQRGQPPKDEEPENNADTVPKRL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O96863-1", "uniprot_id": "CSK2C_DROME", "id": "O96863-1", "name": "Casein kinase II subunit beta'", "aln": "------------------------MTDSDESS-----WIHWFCKQRGNEFFCEVDEEYIQDKFNLNFLDSNVKNYKCALEVILDLNPGSASED--PAEPEL-EASAEKLYGLIHARFILTNRGIELMLDKYNKGEFGTCPRAFCHSQPVLPIGLSDNPGEDMVRIYCPKCNDVYIPKASRHSNLDGAFFGTGFPHMFFMEKPDARPKRAKQKFVPRLYGFKIHPTAYRTAAEIQKDVTMTPVGEIDSPSHI---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38930-1", "uniprot_id": "CSK2C_YEAST", "id": "P38930-1", "name": "Casein kinase II subunit beta'", "aln": "MGSRSENVGTVTREGSRVEQDDVLMDDDSDSSEYVDMWIDLFLGRKGHEYFCDVDPEYITDRFNLMNLQKTVSKFSYVVQYIVDDLDDSILENMTHARLEQLESDSRKLYGLIHARYIITIKGLQKMYAKYKEADFGRCPRVYCNLQQLLPVGLHDIPGIDCVKLYCPSCEDLYIPKSSRHSSIDGAYFGTSFPGMFLQAFPDMVPKHPTKRYVPKIFGFELHKQAQLTRWQELQRLKLVEKLESKDVDLTKSGGFKT--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ...: * *: * :*:*:**:** :** *:*** *:. * :: .:: *:* . *: . : * :. ********:*:* :*: * **: .:** ***.:*. * :**:** * ** *: ***.* *:* **:*** ***:***.** *:: *: **:. :::**:::**::* * : .. ", "identical_positions": 80, "similar_positions": 59, "identity": "30.08%" }, { "cls_id": "homologset.agr.SGD:S000005566", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q69ZP3-1", "uniprot_id": "PNKD_MOUSE", "id": "Q69ZP3-1", "name": "Probable thioesterase PNKD", "aln": "MAAVVAATALKGRGARNARVLRGILSGATANKASQNRTRALQSHSSPECKEEPEPLSPELEYIPRKRGKNPMKAVGLAW---------------------------------------YSLYTRTWLGYLFYRQQLRRARNRYPKGHSKTQPRLFNGVKVLPIPVLSD--NYSYLIIDTQAGLAVAVDPSDPRAVQASIEKE-RVNLVAILCTHKHWDHSGGNRDLSRRHR------DCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFS---------------------------GDLLFLSGCGRTFEGTAETMLSSLDTVLDLG------DDTLLWPGHEYAEENLGFAGVVEPENLARERKMQWVQR----QRMERKSTCPSTLGEERAYNPFLRTHCLELQEALGPGPGPTSDDGCSRAQLLEELRRLKDMHKSK-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZXB0-1", "uniprot_id": "D3ZXB0_RAT", "id": "D3ZXB0-1", "name": "Probable thioesterase PNKD", "aln": "MAAVVAATALKGRGARNARVLRGILSGATANKASQNRTRALQSHSSPECKEEPEPLSPELEYIPRKRGKNPMKAVGLAWAIGFPCGILFFVLTKQEVDKDRLKQMKARQNMRVSNTGEYSLYTRTWLGYLFYRQQLRRARNRFPKGHSKTQPRLFNGVKVLPIPVLSD--NYSYLIIDTQAGLAVAVDPSDPRAVQASIEKE-RVNLVAILCTHKHWDHSGGNRDLSRRHR------DCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFS---------------------------GDLLFLSGCGRTFEGTAETMLSSLDTVLDLG------DDTLLWPGHEYAEENLGFAGVVEPENVARERKMQWVQR----QRMERKSTCPSTLGEERAYNPFLRTHCLALQEALGPGPGPTSDDGCSRAQLLEELRRLKDMHKSK-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N490-1", "uniprot_id": "PNKD_HUMAN", "id": "Q8N490-1", "name": "Probable thioesterase PNKD", "aln": "MAAVVAATALKGRGARNARVLRGILAGATANKASHNRTRALQSHSSPEGKEEPEPLSPELEYIPRKRGKNPMKAVGLAW---------------------------------------YSLYTRTWLGYLFYRQQLRRARNRYPKGHSKTQPRLFNGVKVLPIPVLSD--NYSYLIIDTQAQLAVAVDPSDPRAVQASIEKE-GVTLVAILCTHKHWDHSGGNRDLSRRHR------DCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFS---------------------------GDLLFLSGCGRTFEGNAETMLSSLDTVLGLG------DDTLLWPGHEYAEENLGFAGVVEPENLARERKMQWVQR----QRLERKGTCPSTLGEERSYNPFLRTHCLALQEALGPGPGPTGDDDYSRAQLLEELRRLKDMHKSK-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DB32-1", "uniprot_id": "HAGHL_MOUSE", "id": "Q9DB32-1", "name": "Hydroxyacylglutathione hydrolase-like protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MKVKVIPVLED--NYMYLIIEEHTREAVAIDVAVAERLLEIAGRE-GVSLTMVLSTHHHWDHTRGNAELAHILP------GLAVLGA-DERICALTRRLEHGEGLQFGAIHVRCLLTPGHTSGHMSYFLWEDDCPDSPALFS---------------------------GDALSVAGCGWHLEDTAQQMYQSLAKTLGTLP-----PETKVFCGHEHTLSNLEFAQKVEPCNEHVQAKLSWAQE----RDDEDIPTVPSTLGEELMYNPFLRVTEDAVRAFTG---------QVAPAQVLEALCRERARFQPAVEPPQP-QVRALLALQWGLLSTHQKK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L628-1", "uniprot_id": "A0ABK0L628_RAT", "id": "A0ABK0L628-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MKVKVIPVLED--NYMYLIIEEHTREAVAVDVAVPKRLLEIAGRE-GVSLTTVLSTHHHWDHTRGNAELARLQP------GLAIMGA-DERICALTRRLEHGEELQFGAIHVRCLLTPGHTSGHMSYFLWEDECPDPPALFSGTLQPGLTYQPNSTVSSRPPSDPLCSLGDALSVAGCGWHLEDTAQQMYQSLAKTLGTLP-----PQTKVFCGHEHTLSNLEFAQKVEPCNSHVQAKLSWAQK----RDDDDVPTVPSTLGEELMYNPFLRVTEDPVRAFTG---------QVAPAQVLEVLCRERARFQLASEPPQP-QVRALLALQWGLLSTGQEK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PII5-1", "uniprot_id": "HAGHL_HUMAN", "id": "Q6PII5-1", "name": "Hydroxyacylglutathione hydrolase-like protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MKVKVIPVLED--NYMYLVIEELTREAVAVDVAVPKRLLEIVGRE-GVSLTAVLTTHHHWDHARGNPELARLRP------GLAVLGA-DERIFSLTRRLAHGEELRFGAIHVRCLLTPGHTAGHMSYFLWEDDCPDPPALFS---------------------------GDALSVAGCGSCLEGSAQQMYQSLAE-LGTLP-----PETKVFCGHEHTLSNLEFAQKVEPCNDHVRAKLSWAKARPLSRRGKRVGGEGTGFGVGGALRQGLMVTGACGHSRRG---------MRMTCPLCRRLWARSASTTPSCGWREYGCCPGASTVTWTLRKASGDCVLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99KB8-1", "uniprot_id": "GLO2_MOUSE", "id": "Q99KB8-1", "name": "Hydroxyacylglutathione hydrolase, mitochondrial", "aln": "---------------------MVLGRGS-----LCLRSLSALG-ATCARRG-LGQALLGLSLCHSD-----------------------------------------------------------------FRKNL---------------TVQQDIMKVELLPALTD--NYMYLIIDEDTQEAAIVDPVQPQKVIEAAKKH-HVKLTTVLTTHHHWDHAGGNEKLVKLEP------GLKVYGG-DDRIGALTHKVTHLSTLQVGSLSVKCLSTPCHTSGHICYFVSKPGSSEPSAVFT---------------------------GDTLFVAGCGKFYEGTADEMYKALLEVLGRLP-----PDTKVYCGHEYTVNNLKFARHVEPGNAAIQEKLAWAKE----KYAIGEPTVPSTLAEEFTYNPFMRVKEKTVQQHAG---------ETDPVTTMRAIRREKDQFKVPRD---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35952-1", "uniprot_id": "GLO2_RAT", "id": "O35952-1", "name": "Hydroxyacylglutathione hydrolase, mitochondrial", "aln": "---------------------MVLGRGS-----LCLRSLSVLG-AACARRG-LGQALLGLSLCHTD-----------------------------------------------------------------FRKNL---------------TVQQDMMKIELLPALTD--NYMYLIIDEDTQEAAVVDPVQPQKVIETVKKH-RVKLTTVLTTHHHWDHAGGNEKLVKLEP------GLKVYGG-DDRIGALTHKVTHLSTLEVGSLSVKCLSTPCHTSGHICYFVSKPGSSEPSAVFT---------------------------GDTLFVAGCGKFYEGTADEMYKALLEVLGRLP-----PDTKVICGHEYTVNNLKFARHVEPGNTAVQEKLAWAKE----KNAIGEPTVPSTLAEEFTYNPFMRVKEKTVQQHAG---------ETDPVTTMRAIRREKDQFKVPRD---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16775-1", "uniprot_id": "GLO2_HUMAN", "id": "Q16775-1", "name": "Hydroxyacylglutathione hydrolase, mitochondrial", "aln": "---------------------MVVGRGL-----LGRRSLAALG-AACARRG-LGPALLGV-FCHTD-----------------------------------------------------------------LRKNL---------------TVDEGTMKVEVLPALTD--NYMYLVIDDETKEAAIVDPVQPQKVVDAARKH-GVKLTTVLTTHHHWDHAGGNEKLVKLES------GLKVYGG-DDRIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVSKPGGSEPPAVFT---------------------------GDTLFVAGCGKFYEGTADEMCKALLEVLGRLP-----PDTRVYCGHEYTINNLKFARHVEPGNAAIREKLAWAKE----KYSIGEPTVPSTLAEEFTYNPFMRVREKTVQQHAG---------ETDPVTTMRAVRREKDQFKMPRD---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P963-1", "uniprot_id": "GLO2_DANRE", "id": "Q6P963-1", "name": "Hydroxyacylglutathione hydrolase, mitochondrial", "aln": "---------------------------------MWFRSLAVSA-CTVGVLGALSQKFAPTALFHSA-----------------------------------------------------------------IRKSS---------------LVEQSDMKVELLPALTD--NYMYLLIDEETKEAAIVDPVEPQKVVDAVKKH-GVKLKTVLTTHHHWDHAGGNEKLVKLMP------GLTVYGG-DDRVGALTQKVTHYNTFKVGSLNVKCLFTPCHTSGHICYFVTKENSTEAPAVFT---------------------------GDTLFVAGCGKFFEGTADEMYKALIEVLGRLP-----PETRVYCGHEYTINNLKFARHVEPNNEVIRTKLAWAKE----KYDNGEPTIPSTVAEEFTFNPFMRVREKSVLEHAG---------TSDPIEAMRSIRKEKDGFRVPKN---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IPU3-1", "uniprot_id": "Q8IPU3_DROME", "id": "Q8IPU3-1", "name": "hydroxyacylglutathione hydrolase", "aln": "---MLASAWRSVATSVETQLTATYFRGSSSNPTLLLRSWRTIPRADAPGFGAIRRRFLAVPVICPS-----------------------------------------------------------------LVKLQKLRKVGFRGMHSTLEDVQLEGMEIKILPALQD--NYMYLIVDTKTREAAVVDPVEPELVIKTVQEQ-QLTLSKVLTTHHHWDHAGGNEKLLKLWEK-----ELDVYGG-DDRIGALNKKVQQDDTFTIGGLHVKCLSTPCHTTGHICYHITAQQGSGEGAVFT---------------------------GDTLFQGGCGRFFEGTPEEMYEALCTKLSALP-----DATKVFCGHEYTLQNMSFARHVEPDNEVIQQRIEWAKH----RRASQDPTVPSTIGEEKSWNPFMRVHEATVQKHAGG--------ATDPVVTMGKLRKEKDTFKA------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12320-1", "uniprot_id": "GLO4_YEAST", "id": "Q12320-1", "name": "Hydroxyacylglutathione hydrolase, mitochondrial", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MKFLLQQIRNMHVKPIKMRWLTGGVNYSYLLSTEDRRNSWLIDPAEPLEVSPKLSAEEKKSIDAIVNTHHHYDHSGGNLALYSILCQENSGHDIKIIGG-SKSSPGVTEVPDNLQQYHLGNLRVTCIRTPCHTKDSICYYIKDLETG-EQCIFT---------------------------GDTLFIAGCGRFFEGTGRDMDMALNQIMLRAVGETNWNKVKIYPGHEYTKGNVSFIRAKIYSDIGQNKEFDALEQY---CKSNECTTGHFTLRDELGYNPFMRLDDRAVRLAVGDTAG-----TYPRSVVMQELRKLKNAM--------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : * . ** **: : :* . : . .: :: **:*:**: ** * : *. .. :.. : . .* : : .: ** ** . : * : .:*: ** * .*** *.. * :* : . : ***:: *: * : . .: : . . : * : ", "identical_positions": 37, "similar_positions": 56, "identity": "7.41%" }, { "cls_id": "homologset.agr.SGD:S000005568", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2RUW1-1", "uniprot_id": "TOLIP_RAT", "id": "A2RUW1-1", "name": "Toll-interacting protein", "aln": "------------------------------------------------------------------------------------MATTVSTQRGPVYIGELPQDFLRITPTQQQQQIQLDAQAAQQLQYGGAVGTVGRLSITVVQAKLAKNYGMTRMDPYCRLRLGYAVYETPTAHNGAKNPRWNKVIQCTVPPGVDSFYLEIFDERAFSMDDRIAWTHITIPESLKQGQVEDEWYSLSGRQGDDKEGMINLVMSYT----------------------------------SLPAAMMMPPQPVVLMPTVYQQGVG-------YVPIAGMPAVCSPGMVPMAMPPPA--------VAPQPR-CNEED---LKAIQDMFPNMDREVIRSVLEAQRGNKDAAINSLLQMGEES-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ06-1", "uniprot_id": "TOLIP_MOUSE", "id": "Q9QZ06-1", "name": "Toll-interacting protein", "aln": "------------------------------------------------------------------------------------MATTVSTQRGPVYIGELPQDFLRITPTQQQQQIQLDAQAAQQLQYGGTVGTVGRLSITVVQAKLAKNYGMTRMDPYCRLRLGYAVYETPTAHNGAKNPRWNKVIQCTVPPGVDSFYLEIFDERAFSMDDRIAWTHITIPESLKQGQVEDEWYSLSGRQGDDKEGMINLVMSYT----------------------------------SLPAAMMMPPQPVVLMPTVYQQGVG-------YVPIAGMPAVCSPGMVPMAMPPPA--------VAPQPR-CNEED---LKAIQDMFPNMDREVIRSVLEAQRGNKDAAINSLLQMGEES-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0E2-1", "uniprot_id": "TOLIP_HUMAN", "id": "Q9H0E2-1", "name": "Toll-interacting protein", "aln": "------------------------------------------------------------------------------------MATTVSTQRGPVYIGELPQDFLRITPTQQQRQVQLDAQAAQQLQYGGAVGTVGRLNITVVQAKLAKNYGMTRMDPYCRLRLGYAVYETPTAHNGAKNPRWNKVIHCTVPPGVDSFYLEIFDERAFSMDDRIAWTHITIPESLRQGKVEDKWYSLSGRQGDDKEGMINLVMSYA----------------------------------LLPAAMVMPPQPVVLMPTVYQQGVG-------YVPITGMPAVCSPGMVPVALPPAA--------VNAQPR-CSEED---LKAIQDMFPNMDQEVIRSVLEAQRGNKDAAINSLLQMGEEP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZV43-1", "uniprot_id": "TOLIP_DANRE", "id": "Q7ZV43-1", "name": "Toll-interacting protein", "aln": "------------------------------------------------------------------------------------MATTISTQRGQVYIGELPQDFLRIMPTQQQQQVQLDAQAARQLQYGGSLGTAGRLSITVVQAKLAKNYGMTRMDPYCRIRLGYAVYETPTAHNGAKNPRWNKVIQCTVPPGVDSFYLEIFDERAFSMDDRIAWTHVTIPENLREGTVVDEWYSLSGRQGDDKEGMINLVMSFA----------------------------------TIPAGMMMQPQPVVLMPTVYQQGVG-------YVPIAGVPGMYNQGVVPMGMPAAAP-------VASQSAPCSEED---LKALQDMFPNLDKEVIRTVLEAQQGNKDAAINSLLQMAEEL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08412-1", "uniprot_id": "CUE5_YEAST", "id": "Q08412-1", "name": "Ubiquitin-binding protein CUE5", "aln": "MEEKEGIKDSSLLEKSNVPESINEDISKTTDVDLNSDGKKDNDTSAKDGTPKVEEKVNKSSGIDEDEVVTPAEDAKEEEEEHPPLPARRKSEEEPSKENPILQELKDAFPNLEEKYIKAVIIASQGVLSP-AFNALLFLSDPESGKDIELPTQPVRKNPEAPARRRQTQLEQDELLARQLDEQFNSSHSRRRNRDRATRSMHEQRRRRHNPNEREQHHEDSEEEDSWSQFVEKDLPELTDRAGRSLQDTANKVSNWISDAYRRNFASGNEQNDNQHGHQDQQEWEPEIVDLSQGGKNSRPQQPERRRFNSFGVQVGDDSLESHGITLHNEDGFEDDEDVPPQLPTRTKSGESTGKVVAETTYIDTPDTETKKKWQPLPPEPLDTTPTKVNAVSRNKKNPDEDEFLINSDDEM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: .::. . : *:: *. ::: :: *:: : :..: *. . .: .* :* . * : * : ::*. . : :. .* .. ::* . : *. . * .. .*:.* * . :. * * .: . ** . : ** :.: . .. . ** :*. : * .:. . * * * : *: . .* ..:.:*:. :.:* .:: ", "identical_positions": 33, "similar_positions": 93, "identity": "8.01%" }, { "cls_id": "homologset.agr.SGD:S000005569", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LU70-1", "uniprot_id": "F1LU70_RAT", "id": "F1LU70-1", "name": "", "aln": "MAALDSDSEEDLISYGTGLEPLEEGERP-KKPIPLQDQTVRDEKGRYKRFHGAFSGGFSAGYFNTVGSKEGWTPSTFVSSRQNRAD-KSALGPEDFMDEEDLSEFGIAPKAIVTTDDFASKTKDRIREKAR-----QLAAAAAPIPGATLLDDLITPAKLSVGFELLRKMGWKEGQGVGPRVKRKARRQKADPG------VKIYGCALPPGGSEGSEDED---DDYLPDNVTFAPKDVMPVDFTPKDNVHGLAYKGLDPHQALFGMPGEHLNLFGGASEGTSHLLGDVGLSKGRK-LGISGQAFGVGALEEEDDDIYATETLSKYDTVLKDEEPGDGLYGWTAPKQYKNHKEPERDLRYVGKILEGFSLASKPLSSKKIYPPPELPRDYRPVHYFRPVVAATSKNAHLLQVLSESSGKAGQDMGTHSRHQLNASKRGELLGEMPVQGSATSVLEFLSQKDKERIKEVKQATDLKAAQAKARSLAQSASSSRAQAS-TPDPGHSSWHLALGSG-----TVTTRASNFKPFAKDPEKQRRYEEFLVHMKKGQK---DALERCLDPNMTEWERSREREEFARAAQLYVSSNSTLSSRFTHAKEEDDSDQVEVPRDQENDLSDKQSAVKMKMFGKLTRDTFEWHPDKLLCKRFNVPDPYPGSTLVGLPRVK-RDKYSVFNFLT----------------------LSEPASLPTAPVPSEK--APQQRGPDKSRKPS--------RWDTSKQEKKEDSISEFLSQARSKVGPSKQESSALGSKEE-QASEPHPDMTVDKAVDAQPD--REGSRPSMDLFKAIFASSSDEKSSSSEEEQDDSEDSQ-----EHTEEASLKGSQEAAVGETS-LIHAAEQEPGEPATPFPIQKVQIDE-REEFGPRLPPVFCPNVRQKLEIPHKEKPKKSKERHRSKKEHRRKREKKKKHKKHKHKSKQKNKKSEKNSSSESTDSSDSGSDAGGSTELSPQELLRRLKCLPLRRQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBM1-1", "uniprot_id": "GPTC1_MOUSE", "id": "Q9DBM1-1", "name": "G patch domain-containing protein 1", "aln": "MAALDSDSDEDLISYGTGLEPLDEGERP-KKPIPLQDQTVRDEKGRYKRFHGAFSGGFSAGYFNTVGSKEGWTPSTFVSSRQNRAD-KSALGPEDFMDEEDLSEFGIAPKAIVTTDDFASKTKDRIREKAR-----QLAAAAAPIPGATLLDDLITPAKLSVGFELLRKMGWKEGQGVGPRVKRKARRQKPDPG------VKIYGCALPPGGSEESEDED---DDYLPDNVTFAPKDVMPVDFTPKDNVHGLAYKGLDPHQALFGMPGEHLNLFGGASEGTSHLLGDVGLSKGRK-LGISGQAFGVGALEEEDDDIYATETLSKYDTVLKDEEPGDGLYGWTAPKQYKNQKEPERDLRYVGKILEGFSLASKPLSSKKIYPPPQLPRDYRPVHYFRPVVAATAENAHVLQVLSESSGKAGQDVGTHSRHQLNASKRGELLGEMPIQGSATSVLEFLSQKDKERIKEVKQATDLKAAQAKARSLAQSASSSRAQAS-TPDLGHSSWHLALGGG-----TVTTRANNFKPFAKDPEKQRRYEEFLVHMKKGQK---DALERCLDPSMTEWERSREREEFARAAQLYVSSNSTLSSRFTHAKEEEDSDQVEVPRDQENDVSDKQSAVKMKMFGKLTRDTFEWHPDKLLCKRFNVPDPYPGSTLVGLPRVK-RDKYSVFNFLT----------------------LPEPAPLPTAPVPSEK--APQQRGSDKSRKPS--------RWDTSKQEKKEDSISEFLSQARSKVGPPKQESSALGSKEE-QAPEPRPDTTVDKAVDAQTD--GEGSRPSMDLFKAIFASSSDEKSSSSEEEQDDSEDSQ-----EHTEEASLKGSQEAAAGETS-VVLAAEPEPCEPATPFPIQKAQIDE-REEFGPRLPPVFCPNSRQKLEIPQKEKPKKSKERHKSKKEHRRKREKKKKHKKHKHKSKQKNKKSEKNSSSESTDSSDSGSDDGGPAELSPQELLRRLKCLPLRRQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BRR8-1", "uniprot_id": "GPTC1_HUMAN", "id": "Q9BRR8-1", "name": "G patch domain-containing protein 1", "aln": "MAARDSDSEEDLVSYGTGLEPLEEGERP-KKPIPLQDQTVRDEKGRYKRFHGAFSGGFSAGYFNTVGSKEGWTPSTFVSSRQNRAD-KSVLGPEDFMDEEDLSEFGIAPKAIVTTDDFASKTKDRIREKAR-----QLAAATAPIPGATLLDDLITPAKLSVGFELLRKMGWKEGQGVGPRVKRRPRRQKPDPG------VKIYGCALPPGSSEGSEGED---DDYLPDNVTFAPKDVTPVDFTPKDNVHGLAYKGLDPHQALFGTSGEHFNLFSGGSE-RAGDLGEIGLNKGRK-LGISGQAFGVGALEEEDDDIYATETLSKYDTVLKDEEPGDGLYGWTAPRQYKNQKESEKDLRYVGKILDGFSLASKPLSSKKIYPPPELPRDYRPVHYFRPMVAATSENSHLLQVLSESAGKATPDPGTHSKHQLNASKRAELLGETPIQGSATSVLEFLSQKDKERIKEMKQATDLKAAQLKARSLAQNAQSSRAQLSPAAAAGHCSWNMALGGG-----TATLKASNFKPFAKDPEKQKRYDEFLVHMKQGQK---DALERCLDPSMTEWERGRERDEFARAALLYASSHSTLSSRFTHAKEEDDSDQVEVPRDQENDVGDKQSAVKMKMFGKLTRDTFEWHPDKLLCKRFNVPDPYPDSTLVGLPRVK-RDKYSVFNFLT----------------------LPETASLPTTQASSEK--VSQHRGPDKSRKPS--------RWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVNKDVDAQAE--GEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQ-----AGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDE-REEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEE-TADVSPQELLRRLKSLPLRRQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VUA0-1", "uniprot_id": "GPTC1_DROME", "id": "Q9VUA0-1", "name": "G patch domain-containing protein 1 homolog", "aln": "-----MDEEEHLHRFGTPLPALQKDVVPAKKPVAIEDQIVKDENGK-RRFHGAFTGGFSAGFWNTVGSLEGWTPQTFKSSRGERASSKAQLKPEDFMDQEDLGEFGIAPQGIRTRDEFANEDEQKQRSDQRRRKLMQPELGVGAIPGLPVLEQLLRPVRDKVAVRILKSMGWKPGQGVGPRQTRKEKRQATARNSKEQYLMEHYGAEGLPSNKENKGEEDSNNEDEDDEDITFAPDDYEPIFYTPKENRFGMSYSGLNRDPILSKSS-----SSSAKPMQHINLFGEMEAQANKKQLSIRGQAFGVGAFEEEDEDIYARDDMTRYDFSLADKKP----------KQKKQQHVQQR------HVIDGFSEDNSPAVLQRPY-AIDLPRDFQPRNWLQRRSRFAPMDKERAQKLETASEYKRSGLG---RHDLNPDQRAQILGEQQQEEKTAEEQPKRNPFKDHSKSLMERINARTEGFTKGGVITENGEEQQTELAKEVKEANAAIQERAALKTKDLPSAMNSSSAFKPFIADEAKQLRYEKFVSSKLTDDKEITEFLARMQPVTLSLWDREMEKKEFIQAAKIYRPLVGLMNDRFVSEAN----VQAEKVEQQEKPPEERK--------IVMERTKTMWKPTALLCKRYNIAEPFGGAMLEPEKELKAKAKISVFDYLETSVNTKANFETPSIFPKHIEKSIPEKVETPPSPPPAPQPEAEIQDKPNTKEEPSKHTFVPKTPLEQAVDESRNKPISEKVDLFKSIFEDSDEEETELSEQDKLAILQESFGLPVTSTTSAAAQNVLRNTSPPRGIFASLFSPKIKDAAKEPAPTKFGPIEGSKLKIAYKPRKERLRNDRELAMAEVAPEDIYGPKLPTAPPQKPAAPEIQAEANIDDRLQQLWQQHAPKKRKAEKWVEKKCISGSEDSDASSSNESSSSDSSDDNDKRSKLSKPK--KSHKGSSSKKSKKSKLKSKKKSKKSEESKHKAKKKKKKSKH--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12611-1", "uniprot_id": "WHI2_YEAST", "id": "P12611-1", "name": "Growth regulation protein", "aln": "------------------MDDIITQVSP-----------------------------------------DNAESAPILQEQQQQQNSQYEGNEEDYGDS-------LIHLNIQENHYFITRDQ------------------LMSLPESLLLCLFPSGVFLDRCGQVITNLTRDD---------------------------EVYIVNFPP--------------DCFEYIMEIYTKAHDDLYNHPVEKFFDRPSS-----------------SFVSNAKGFFGLSSNNSISSNNE-QDILHQKPAIIVLREDLDYYCVPQEEFQFDSTNEENNE-------------------------------------------------DLLRHFMAQVKMAAGSYLTSKTSIFQGLYSS--------------NRLKQQQQQQKIEKGSNSSSNTKSTSKKLGPAEQHLMDMLCSSGFTKETCWGNRTQETGKTVISSLS-------------------------------------------------------------LCRLANETTEGFRQKFN------------------------------------------------------------EAKAKWEAEHKPSQDNFITPMQSNISINSLSASKSNSTISTARNLT---------------------------SGSTAPATARD-----------KRKS---------RLSKLADNVRSHSSSRHSSQTRSKPPELPKLYDLVPKPNINAKLLLFWRKPARKCWWGEED---------IELEVEVFGSWKDESKK-----------------------------------------IIELILPTNVDPEAELHKIIVPVRLHIRRVWTLELSVIGVQ-----------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * :. . .: ..: :: . : **: *. : * . * .. : .:* :* : . . .:: .: . : * * * : : .. : * :: .. . . . . .: . ..: .* * .: .:.*: : . : ::* ::: :* *.: . : :. . : *: .:: : : : . . :. .. : . . . :... :. : * * . : : : . . *.. .: :. . : * . . *. * ..: .: . ..:. . .: :... *. . :* : : . : .. . . : : :*.. .: . * : . : ", "identical_positions": 29, "similar_positions": 157, "identity": "2.9%" }, { "cls_id": "homologset.agr.SGD:S000005572", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61655-1", "uniprot_id": "DD19A_MOUSE", "id": "Q61655-1", "name": "ATP-dependent RNA helicase DDX19A", "aln": "MATDSWA--LAVDEQEAAVKSMSSLQIKEEKVK-ADTN-G-VIKTSTTAEKTEE--EEKEDRAAQSLLNKLIRSNLVDNTNQVEVL----QRDPSSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPMMLAEPPQNLIAQSQSGTGKTAAFVLAMLSRVEPADRYPQCLCLSPTYELALQTGKVIEQMGKFHPELKLAYAVRGNKLERGQKVSEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNIIKLKREEETLDTIKQYYVLCNNREEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVN------MVDSKHSMNILNRIQEHF-NKKIERLDTD--------------DLDEIEKIAN-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NUU7-1", "uniprot_id": "DD19A_HUMAN", "id": "Q9NUU7-1", "name": "ATP-dependent RNA helicase DDX19A", "aln": "MATDSWA--LAVDEQEAAVKSMTNLQIKEEKVK-ADTN-G-IIKTSTTAEKTDE--EEKEDRAAQSLLNKLIRSNLVDNTNQVEVL----QRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPMMLAEPPQNLIAQSQSGTGKTAAFVLAMLSRVEPSDRYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVN------MVDSKHSMNILNRIQEHF-NKKIERLDTD--------------DLDEIEKIAN-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UMR2-1", "uniprot_id": "DD19B_HUMAN", "id": "Q9UMR2-1", "name": "ATP-dependent RNA helicase DDX19B", "aln": "MATDSWA--LAVDEQEAAAESLSNLHLKEEKIK-PDTN-GAVVKTNANAEKTDE--EEKEDRAAQSLLNKLIRSNLVDNTNQVEVL----QRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVN------MVDSKHSMNILNRIQEHF-NKKIERLDTD--------------DLDEIEKIAN-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JUH2-1", "uniprot_id": "A0A0G2JUH2_RAT", "id": "A0A0G2JUH2-1", "name": "RNA helicase", "aln": "MATDSWA--LAVDEQEAAAESVSCHQPFEQHLY-FVSNQGAVVKTSANTEKTEE--DEKEDRAAQSLLNKLIRSNLVDNTNQVEVL----QRDPSSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANNHPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKVGEQIVIGTPGTVLDWCSKMKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNIIKLKREEETLDTIKQYYVLCNNREEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVN------MVDSKHSMNILNRIQEHF-NKKIERLDTD--------------DLDEIEKIAN-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QY15-1", "uniprot_id": "DDX25_MOUSE", "id": "Q9QY15-1", "name": "ATP-dependent RNA helicase DDX25", "aln": "MASLLWGGDAGAAESERLNSHFSNLVHPRKNLRGIRSTTVPNIDGSLNTEDDDDDEDDVVDLAANSLLNKLIRQSLIESSHRVEVL----QKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFPQCLCLAPTYELALQTGRVVERMGKFCVDVEVMYAIRGNRIPRGTEVTKQIIIGTPGTVLDWCFKRKLIDLTKIRVFVLDEADVMIDTQGFSDQSIRIQRALPSECQMLLFSATFEDSVWQFAERIIPDPNVIKLRKEELTLNNIRQYYVLCENRKGKYQALCNIYGGITIGQAIIFCQTRRNAKWLTVEMMQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVNQSEEPDYETYLHRIGRTGRFGKKGLAFN------MIEVDK-LPLLMKIQDHF-NSNIKQLDPE--------------DMDEIEKIEY-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QY16-1", "uniprot_id": "DDX25_RAT", "id": "Q9QY16-1", "name": "ATP-dependent RNA helicase DDX25", "aln": "MASLLWGGDAGAAESERLNSHFSNLVHPRKNLRGIRSTTVPNIDGSLNTEEDDD-EDDVVDLAANSLLNKLIRQSLVESSHRVEVL----QKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLNRVNALELFPQCLCLAPTYELALQTGRVVERMGKFCVDVEVMYAIRGNRIPRGTDVTKQIVIGTPGTVLDWCFKRKLIDLTKIRVFVLDEADVMIDTQGFSDQSIRIQRALPSECQMLLFSATFEDSVWQFAERIIPDPNVIKLRKEELTLNNIRQYYVLCENRKDKYQALCNIYGGITIGQAIIFCQTRRNAKWLTVEMMQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVNQSEEPDYETYLHRIGRTGRFGKKGLAFN------MIEVDK-LPLLMKIQDHF-NSSIKQLDPE--------------DMDEIEKIEY-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UHL0-1", "uniprot_id": "DDX25_HUMAN", "id": "Q9UHL0-1", "name": "ATP-dependent RNA helicase DDX25", "aln": "MASLLWGGDAGAAESERLNSHFSNLSQPRKNLWGIKSTAVRNIDGSINNINEDD-EEDVVDLAANSLLNKLIHQSLVESSHRVEVL----QKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFPQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIPRGTDITKQIIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQMLLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLNNIRQYYVLCEHRKDKYQALCNIYGSITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFN------MIEVDE-LPSLMKIQDHF-NSSIKQLNAE--------------DMDEIEKIDY-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O61305-2", "uniprot_id": "DDX19_DROME", "id": "O61305-2", "name": "DEAD-box helicase Dbp80", "aln": "MG--DWA---KKAEDQEVSKLVDKLNLD-----------------SKSGEETDF---DVADPAETSLLIKILGKGLVNTKLSLDIQ----QKNPNSPLHSVKTFEALHLKASLLKGIYAMGFNTPSKIQETALPTLLADPPQNMIAQSQSGTGKTAAFVLAMLSRVNVCLNHPQVLCLSPTYELAIQTGEVAARMGQFCREIKLRFAVRGEEVDRSKKIEEHILIGTPGKLLDWGIKFRLFDMKKISVFVLDEADVMIATQGHHDQCIRIHKMLNPHCQMLFFSATYGKEVMDFARLIVADPTIIRLMREEESLENIKQYYVKCKNEEGKYNAIQNIYGCISVGQAIIFCHTKRTAAWLAAKMTSDGHSVAVLTGDLTVVQRLDVLDRFRSGLEKVLITTNILSRGIDIEQVTIVVNFDLPVDLDGMADCETYLHRIGRTGRFEPSALTRNSPIFGVKAESGKIGKEINRSSSGA-ESGSREMPKEKENISLLKFFSLTGNLDEAWDVQSE----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20449-1", "uniprot_id": "DBP5_YEAST", "id": "P20449-1", "name": "ATP-dependent RNA helicase DBP5", "aln": "----------MSDTKRDPADLLASLKIDNEKEDTSEVSTKETVKSQPEKTADSIKPAEKLVPKVEEKKTKQEDSNLISSEYEVKVKLADIQADPNSPLYSAKSFDELGLAPELLKGIYAMKFQKPSKIQERALPLLLHNPPRNMIAQSQSGTGKTAAFSLTMLTRVNPEDASPQAICLAPSRELARQTLEVVQEMGKFT-KITSQLIVP-DSFEKNKQINAQVIVGTPGTVLDLMRR-KLMQLQKIKIFVLDEADNMLDQQGLGDQCIRVKRFLPKDTQLVLFSATFADAVRQYAKKIVPNANTLELQTNEVNVDAIKQLYMDCKNEADKFDVLTELYGLMTIGSSIIFVATKKTANVLYGKLKSEGHEVSILHGDLQTQERDRLIDDFREGRSKVLITTNVLARGIDIPTVSMVVNYDLPTLANGQADPATYIHRIGRTGRFGRKGVAIS------FVHDKNSFNILSAIQKYFGDIEMTRVPTD--------------DWDEVEKIVKKVLKD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . . . . : . * ..*:.. :.: * :*.***:*.*:*: * * .**:*:*** *: ****** *** :* .**:*:************** *:**.:*: ** :**:*: *** ** .* .**:* .: : : . :. .: ::::****.:** : :::: ** :******* *: ** *:.**::: * . *:::****: . * .:*. ::.:.. :.* :* .:: *:* *: *. . *::.: ::** :::..::** *::.* * :: .:**.*::* *:: . :* ::: **.* .***:***: :****: *::*:*:***. . .* **:********* .:: . . . : .. : .: : : ** .: ", "identical_positions": 146, "similar_positions": 152, "identity": "28.35%" }, { "cls_id": "homologset.agr.SGD:S000005574", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A914-1", "uniprot_id": "D4A914_RAT", "id": "D4A914-1", "name": "5'-3' exoribonuclease", "aln": "MGVPAFFRWLSRKYPSIIVNCVEEKPKECN-GVKIPVDASKPNPNDVEFDNLYLDMNGIIHPCTHPEDKPAPKNEDEMMVAIFEYIDRLFNIVRPRRLLYMAIDGVAPRAKMNQQRSRRFRASKEGMEAAVEKQRVREEILAKGGFLPPE-EIKERFDSNCITPGTEFMDNLAKCLRYYIADRLNNDPGWKNLTVILSDASAPGEGEHKIMDYIRRQRAQPNHDPNTHHCLCGADADLIMLGLATHEPNFTIIREEFKPNKPKPCALCNQFGHEVKDCEGLPREKKGKHDELADSLPCAEGEFIFLRLNVLREYLERELTMASLPFPFDVERSIDDWVFMCFFVGNDFLPHLPSLEIREGAIDRLVNIYKNVVHKTGGYLTESGYVNLQRVQMIMLAVGEVEDSIFKKR----KDDEDSFRRRQKEKRKRMKRDQPAFTPSGILTPY------ALGSRNSPGCQVA---------SNPRQAAYEMRMQSNS----------------SPSISPNTSFASDGSPSPLGGLKRKAEDSDSEPE-----------------------------------------------------------------PEDNVRLWEAGWKQRYYKNKFDVDAAD-EKFRRKVVQSYVEGLCWVLRYYYQGCASWKWYYPFHYAPFASDFEGIADMPSEFEKGTKPFKPLEQLMGVFPAASGNFLPPTWRKLMSDPDSSIIDFYPEDFAIDLNGKKYAWQGVALLPFVDERRLRAALEEVYPDLTPEENRRNSLGSDVLFVGKVHPLHD-FILELYQTGSTEPVDVP--PELCHGIQGKFSLDEEAILPDQTVCSPVPMLRDLTQNTAISINFKDPQFAEDYVFKAIMLPGARKPAAVLKPGDWE---KSSNGRQWKPQLGFNRDRRPVHLDQAAFRTLGHVIPRGSGTGVYSNTAPPPANYQGNVYRPLLRGQAQIPKLMSNMRPQDNWRGPPPLFQQQRFDRSVG--AEPLLPWNRMLQTQNAAFQPNQYQMLAGPGGYPPRRDDHRGGRQGYPREGRKYPLPPPSGRYSWN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBR1-1", "uniprot_id": "XRN2_MOUSE", "id": "Q9DBR1-1", "name": "5'-3' exoribonuclease 2", "aln": "MGVPAFFRWLSRKYPSIIVNCVEEKPKECN-GVKIPVDASKPNPNDVEFDNLYLDMNGIIHPCTHPEDKPAPKNEDEMMVAIFEYIDRLFNIVRPRRLLYMAIDGVAPRAKMNQQRSRRFRASKEGMEAAVEKQRVREEILAKGGFLPPE-EIKERFDSNCITPGTEFMDNLAKCLRYYIADRLNNDPGWKNLTVILSDASAPGEGEHKIMDYIRRQRAQPNHDPNTHHCLCGADADLIMLGLATHEPNFTIIREEFKPNKPKPCALCNQFGHEVKDCEGLPREKKGKHDELADSLPCAEGEFIFLRLNVLREYLERELTMASLPFPFDVERSIDDWVFMCFFVGNDFLPHLPSLEIREGAIDRLVNIYKNVVHKTGGYLTESGYVNLQRVQMIMLAVGEVEDSIFKKR----KDDEDSFRRRQKEKRKRMKRDQPAFTPSGILTPH------ALGSRNSPGCQVA---------SNPRQAAYEMRMQRNS----------------SPSISPNTSFASDGSPSPLGGIKRKAEDSDSEPE-----------------------------------------------------------------PEDNVRLWEAGWKQRYYKNKFDVDAAD-EKFRRKVVQSYVEGLCWVLRYYYQGCASWKWYYPFHYAPFASDFEGIADMSSEFEKGTKPFKPLEQLMGVFPAASGNFLPPTWRKLMSDPDSSIIDFYPEDFAIDLNGKKYAWQGVALLPFVDERRLRAALEEVYPDLTPEENRRNSLGGDVLFVGKLHPLRD-FILELYQTGSTEPVDVP--PELCHGIQGTFSLDEEAILPDQTVCSPVPMLRDLTQNTAVSINFKDPQFAEDYVFKAAMLPGARKPATVLKPGDWE---KSSNGRQWKPQLGFNRDRRPVHLDQAAFRTLGHVTPRGSGTSVYTNTALPPANYQGNNYRPLLRGQAQIPKLMSNMRPQDSWRGPPPLFQQHRFERSVG--AEPLLPWNRMIQNQNAAFQPNQYQMLGGPGGYPPRRDDHRGGRQGYPREGRKYPLPPPSGRYSWN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0D6-1", "uniprot_id": "XRN2_HUMAN", "id": "Q9H0D6-1", "name": "5'-3' exoribonuclease 2", "aln": "MGVPAFFRWLSRKYPSIIVNCVEEKPKECN-GVKIPVDASKPNPNDVEFDNLYLDMNGIIHPCTHPEDKPAPKNEDEMMVAIFEYIDRLFSIVRPRRLLYMAIDGVAPRAKMNQQRSRRFRASKEGMEAAVEKQRVREEILAKGGFLPPE-EIKERFDSNCITPGTEFMDNLAKCLRYYIADRLNNDPGWKNLTVILSDASAPGEGEHKIMDYIRRQRAQPNHDPNTHHCLCGADADLIMLGLATHEPNFTIIREEFKPNKPKPCGLCNQFGHEVKDCEGLPREKKGKHDELADSLPCAEGEFIFLRLNVLREYLERELTMASLPFTFDVERSIDDWVFMCFFVGNDFLPHLPSLEIRENAIDRLVNIYKNVVHKTGGYLTESGYVNLQRVQMIMLAVGEVEDSIFKKR----KDDEDSFRRRQKEKRKRMKRDQPAFTPSGILTPH------ALGSRNSPGSQVA---------SNPRQAAYEMRMQNNS----------------SPSISPNTSFTSDGSPSPLGGIKRKAEDSDSEPE-----------------------------------------------------------------PEDNVRLWEAGWKQRYYKNKFDVDAAD-EKFRRKVVQSYVEGLCWVLRYYYQGCASWKWYYPFHYAPFASDFEGIADMPSDFEKGTKPFKPLEQLMGVFPAASGNFLPPSWRKLMSDPDSSIIDFYPEDFAIDLNGKKYAWQGVALLPFVDERRLRAALEEVYPDLTPEETRRNSLGGDVLFVGKHHPLHD-FILELYQTGSTEPVEVP--PELCHGIQGKFSLDEEAILPDQIVCSPVPMLRDLTQNTVVSINFKDPQFAEDYIFKAVMLPGARKPAAVLKPSDWE---KSSNGRQWKPQLGFNRDRRPVHLDQAAFRTLGHVMPRGSGTGIYSNAAPPPVTYQGNLYRPLLRGQAQIPKLMSNMRPQDSWRGPPPLFQQQRFDRGVG--AEPLLPWNRMLQTQNAAFQPNQYQMLAGPGGYPPRRDD-RGGRQGYPREGRKYPLPPPSGRYNWN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VM71-1", "uniprot_id": "XRN2_DROME", "id": "Q9VM71-1", "name": "5'-3' exoribonuclease 2 homolog", "aln": "MGVPAFFRWLSRKYPSVIIECNENKQVDADTGRNIYEDPTLPNPNGIEFDNLYLDMNGIIHPCTHPEDKPAPKNEDEMMVAIFECIDRLFGIVRPRKLLYMAIDGVAPRAKMNQQRSRRFRAAKETTEKRLEIARIREELLSRGCKLPPEKEKGEHFDSNCITPGTPFMDRLSKCLHYFVHDRQNNNPAWKGIKVILSDANVPGEGEHKIMDYIRKQRAQPDHDPNTQHVLCGADADLIMLGLATHEPNFTIIREEFLPNKPRPCDICNGFGHEMDKCVGLGATAPTSANFKPDVPIGAEVKFIFVRLSVLREYLKQTLEMPNLPFEYSFERALDDWVFMCFFVGNDFLPHLPSLEIREGAVDRLVELYKKCVYKTRGYLTDSGDVNLDRVQLIMTDLGNAEDQIFKSR----QRREEQFKARDK-ARKRQERNQ----DHGSLNQS------AFG-----ASAVG---------PNSQQRSVGNYKEEAA----------------ALRNRKRTSDMAN-------------LDDEDEEE-----------------------------------------------------------------NNDEVRLWEDGFKDRYYESKFDVAPGN-QQFRYAVALQYVRGLCWVLKYYYQGCASWNWYFPYHYAPFASDFVNIQGLSTMFEKGTKPFNPLEQLMGVFPAASSSHVPEPWAKLMSDPESPIIDFYPEDFKIDLNGKKFAWQGVALLPFVDEKRLFKALVPYYDQLTGEEVKRNKRGDNYLYISNQSPHYK-KVKKISEK--DDESVCK--AISFDGMRGTLGKTELNTAISGVLKSPISGLSDINDNITVTTTFRDPEYDEDYIFEAKRLENAVDPPQVLP--------NEQSGNKHRPVIGFNSHLTRAYVPDSGHRMLNAGIRNQQGGG--GNGGGGGGYGQGGGYGQGIGGNQGQSYQNNSRNYNYNYNNNYNQHQGGGYQNNYNNRQQQQYGHNQRFNQDNSNQQQRNFNNYNGPR------------NNNYQQQGGSRQQNQNYRRF---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02792-1", "uniprot_id": "XRN2_YEAST", "id": "Q02792-1", "name": "5'-3' exoribonuclease 2", "aln": "MGVPSFFRWLSRKYPKIISPVLEEQPQIVD-GVILPLDYSASNPNG-ELDNLYLDMNGIVHPCSHPENKPPPETEDEMLLAVFEYTNRVLNMARPRKVLVMAVDGVAPRAKMNQQRARRFRSARDAQIENEAREEIMRQREEVGEIIDDAVRNKKTWDSNAITPGTPFMDKLAAALRYWTAFKLATDPGWKNLQVIISDATVPGEGEHKIMNFIRSQRADPEYNPNTTHCIYGLDADLIFLGLATHEPHFKILREDVFAQD-------NRKRNNLKDTINMTEEEKQFLQKQN-----SEQPFLWLHINVLREYLSAELWVPGLPFTFDLERAIDDWVFMCFFCGNDFLPHLPCLDVRENSIDILLDIWKVVLPKLKTYMTCDGVLNLPSVETLLQHLGSREGDIFKTRHIQEARKKEAFERRKAQKNMSKGQDRHPTVATEQLQMYDTQGNLAKGSWNLTTSDMVRLKKELMLANEGNEEAIAKVKQQSDKNNELMKDISKEEIDDAVSKANKTNFNLAEVMKQKIINKKHRLEKDNEEEEIAKDSKKVKTEKAESECDLDAEIKDEIVADVNDRENSETTEVSRDSPVHSTVNVSEGPKNGVFDTDEFVKLFEPGYHERYYTAKFHVTPQDIEQLRKDMVKCYIEGVAWVLMYYYQGCASWNWFYPYHYAPLATDFHGFSHLEIKFEEGT-PFLPYEQLMSVLPAASGHALPKIFRSLMSEPDSEIIDFYPEEFPIDMNGKKMSWQGIALLPFIDQDRLLTAVRAQYPLLSDAERARNIRGEPVLLISNKNANYERFSKKLYSKENNNNNVVVKFQHFKSGLSGIVSKDVEGFELNGKIVCPIQGGSLPNLSTTLILKMSYRLIPLPSRNKSIILNGFIPSEPVLTAYDLDSIMYKYNNQNYSRRWNFGNDLKQNIVP-VGPKGITQYKPR-------------TGGYRAFFYFAELSRNNVQPAHNYGRNSYNSQPG----FNNSRYDGGNN------------NYRQNSNYRNNNYSGNRNSGQYS---------GNSYSRNNKQSRYDNSRANRR--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:**********.:* *:: : * : * : .***. *:**********:***:***:**.*:.****::*:** :*::.:.***::* **:*************:****:::: .: .: * : . : :***.***** ***.*: .*:*: : .:*.**.: **:***..*********::** ***:*:::*** * : * *****:********:*.*:**:. .:. * :::.. .: : :* *:::::.******. * :..*** :..**::********* *********.*::**.::* *::::* : * *:* .* :** *: :: :*. *..***.* :: *. *. . ::: * * * . : : .: : : : .*. :.:.* * :: *:*:* *:::*** **.* . : :::* :. *:.*:.*** *********:*::*:****:*:** .: : **:** ** * ****.*:****. :* : .***:*:* *******:* **:**** :***:*****:*: ** *: * *: * ** * * :.: . . :: .. : *: * .. . : .*: . . .: .: :: * . . ** . ...: .*. . : . : : . :. * : : . . . . . .: :: . . :*: : .::. .. :.* ::. . . ", "identical_positions": 291, "similar_positions": 257, "identity": "27.4%" }, { "cls_id": "homologset.agr.SGD:S000005580", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A6H7-1", "uniprot_id": "A0A8I6A6H7_RAT", "id": "A0A8I6A6H7-1", "name": "Phosphopantothenoylcysteine decarboxylase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTTTPRSHRTKLRLPECHAITSFSLESFRAGKALDTAILGGILQLILLSSQKATRSR-------------MEPEAPCP------------ASIPSVERKFHVLVGVTGSVAALKLPLLVSKLLDIPG---LEVTVVTTERAKHFYSPQDVP----------------------------------------------------------------------------------------------VTLYSDADEWEMWKRRSDPVLHIDLRRWADLMVVAPLDANTLGKVASGICDNLLTCVIRAWDLNKPLLFCPAMNTAMWEHPLTAQQVGQLKAFG---YVEIPCVSKKLVCGDQGLGAMAEVEIIVAKVKDVLFQHGGIQQS------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZB2-1", "uniprot_id": "COAC_MOUSE", "id": "Q8BZB2-1", "name": "Phosphopantothenoylcysteine decarboxylase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPKAPCP------------AAVPSEERKFRVLVGVTGSVAALKLPLLVSKLLDVPG---LEVTVVTTERAKHFYSPQDVP----------------------------------------------------------------------------------------------VTLYSDADEWEMWKRRSDPVLHIDLRRWADLMLVAPLDANTLGKVASGICDNLLTCVIRAWDLNKPLLFCPAMNTAMWEHPLTAQQVAQLKAFG---YVEIPCVSKKLVCGDQGLGAMAEVETIVAKVQAVLSQHGSIQQS------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96CD2-1", "uniprot_id": "COAC_HUMAN", "id": "Q96CD2-1", "name": "Phosphopantothenoylcysteine decarboxylase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPKASCP------------AAAPLMERKFHVLVGVTGSVAALKLPLLVSKLLDIPG---LEVAVVTTERAKHFYSPQDIP----------------------------------------------------------------------------------------------VTLYSDADEWEIWKSRSDPVLHIDLRRWADLLLVAPLDANTLGKVASGICDNLLTCVMRAWDRSKPLLFCPAMNTAMWEHPITAQQVDQLKAFG---YVEIPCVAKKLVCGDEGLGAMAEVGTIVDKVKEVLFQHSGFQQS------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08438-1", "uniprot_id": "VHS3_YEAST", "id": "Q08438-1", "name": "Phosphopantothenoylcysteine decarboxylase subunit VHS3", "aln": "MTNKSSLKNNRKGVASNTLSGAEQANIGSSAMPDTNSTGPFSSVSSLDTPVVRKSTSPTGSQTKSIMNASGTSGAVVSNTPEPGLKRIPTVTFSDPKLGSLRSDVEQTPPNQVARQSSEKKATSVHIAAEGANQGRNLKDINTKVPKDGEASASSFSTPTSILSNADMGNNISSLLAKKLSFTGGTDSILNSDNSSDSPRKEHPHFYVEDPLHTPSVRSRSNSTSPRPSVVVNTFNPINIEREGSISKTGEPTLLESVLEEAMSPNAVSNPLKRENIMTNMDPRLPQDDGKLHVLFGATGSLSVFKLKHMIRKLEEIYGRDKICIQVILTNSATKFFAMKYMRKNKKQHNSIDTSFNSTNSNAGNITGNKKKVASLEKFSIQKTSSNSAASQTNNKQEEEKQMASTTGFPSTLGGSRTYSNSSNVVSQHPQIELPAHIQFWTDQDEWDVWRQRTDPVLHIELRRWADILVVAPLTANTLAKIALGLCDNLLTSVIRAWNPTFPIFLAPSMGSGTFNSIMTKKHFRIIQEEMPWVTVFKPSEKVMGINGDIGLSGMMDANEIVGKIVVKLGGYPDVSAGKEEEEDEDNDEEDDNKKNDTGGKDEDNDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDEDEDEDDEGKKKEDKGGLQRS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.*:* . . * : *::**.*.***::.:** :: ** :: * : : *: *: *.:*:: : : : :::* ***::*: *:******:******:::**** ****.*:* *:******.*:***: . *:::.*:*.:. :: :* ::. :: * *. : ** **..* :. ** *: * : ... . ", "identical_positions": 74, "similar_positions": 74, "identity": "10.98%" }, { "cls_id": "homologset.agr.SGD:S000005582", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6VEU1-1", "uniprot_id": "NOB1_RAT", "id": "Q6VEU1-1", "name": "RNA-binding protein NOB1", "aln": "-MAP----VEHVVADAGAFLRD--APLQDIGKNIYTIREVVREIRDKATRRRLAVLP--YELRFKEPFPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEF-VGVSHLKKEP----EKVKVSSSIQHPETPLHIS-----GFHLPS-----KSKALQETVDHGPPADGSE-----------------------NLEFSSFMFWRN----------------------PLPNIDHELQQLLIDGRE---EEEEEEEEEEEEDELEDSDDDGG---GWITPSNIKQIQHESE-QCDIP-KDVQVGCVTTDFAMQNVLLQMGLHVLAVN-GMLVREARSYILRCHGCFKTTSDMN----RVFCGHCG-NKTLKKVSVTINDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGG----KYAVNPHLTEDQRFPQLRLSHKARQKTNVFAPDYIAGVSPFAEN-DISSRSAILQVRDSMLGAGRRR-LNPNASRKKFVKKR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BW10-1", "uniprot_id": "NOB1_MOUSE", "id": "Q8BW10-1", "name": "RNA-binding protein NOB1", "aln": "-MAP----VEHVVADAGAFLRD--APLQDIGKNIYTIREVVREIRDKATRRRLAVLP--YQLRFKEPLPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEF-VGVSHLKKEP----EKAKVSSSIQHPETALHIS-----GFHLPS-----KSKPLQEAVDRGHAADGPE-----------------------NLEFSSFMFWRT----------------------PLPNIDRELQELLIDGRE---EEEEEEE-------CEDSDDDGG---GWITPSNIKQIQQELE-QCDTP-EDVQVGCVTTDFAMQNVLLQMGLHVLAVN-GMLVREARSYILRCHGCFKTTSDMN----RVFCGHCG-NKTLKKVSVTINDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGG----KYAINPHLTEDQRFPQLRLSQKARQKTDVFAPDYIAGVSPFAEN-DISSRSAILQVRDGMLGAGRRR-LNPNASRKKFVKKR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULX3-1", "uniprot_id": "NOB1_HUMAN", "id": "Q9ULX3-1", "name": "RNA-binding protein NOB1", "aln": "-MAP----VEHVVADAGAFLRH--AALQDIGKNIYTIREVVTEIRDKATRRRLAVLP--YELRFKEPLPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEF-VGVSHLKQEP----QKVKVSSSIQHPETPLHIS-----GFHLPY-----KPKPPQE-TEKGHSACEPE-----------------------NLEFSSFMFWRN----------------------PLPNIDHELQELLIDRGEDVPSEEEEEEENGFEDRKDDSDDDGG---GWITPSNIKQIQQELE-QCDVP-EDVRVGCLTTDFAMQNVLLQMGLHVLAVN-GMLIREARSYILRCHGCFKTTSDMS----RVFCSHCG-NKTLKKVSVTVSDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGG----KYAINPHLTEDQRFPQLRLSQKARQKTNVFAPDYIAGVSPFVEN-DISSRSATLQVRDSTLGAGRRR-LNPNASRKKFVKKR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W2Y4-1", "uniprot_id": "Q9W2Y4_DROME", "id": "Q9W2Y4-1", "name": "RNA-binding protein NOB1", "aln": "-MAETSEKIKFLVADTTAFINA--VPLNEYAEQVLTVPDVVAEVRNKRQIRRLCVLP--FDLQVREPRPESIKHCVEFAKKTGDYASLSGIDLKVISLTYELEADN-VGTDHLRQEP----VMAQTIASKDKPEEMQDANNKRLVGWYMPEGEEE-EEEDSEEEDDYSQEEDDAEGDEQEANESPDTVKAAIEAQLAGKEPFASETIEKEEDQDQEPSQEELDKLFEQLKCAPSAEEEKELSELLVSQPA---EVDEEVSEPQEAKQSQNLDEDVGDD-GWITHSNIKKAKKALEGKVETD-EVPPVACMTTDYALQNVLKQLNLHLAALN-GRIIKQLRTYILRCYACYKTTSIMT----KVFCPNCG-NKTLKRVAVSLDENGRQVIHIN-TRRPLTNKYKNQSLPRFQGG----KHSRNPILFEDQPMPRQMPSRVAKTKTNALDQDYTAGFSPFVLR-DVDSKSAMLRSKGNLKEWARNNNFEEDRRRKNYNRLYK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08444-1", "uniprot_id": "NOB1_YEAST", "id": "Q08444-1", "name": "20S-pre-rRNA D-site endonuclease NOB1", "aln": "MTENQTAHVRALILDATPLITQSYTHYQNYAQSFYTTPTVFQEIKDAQARKNLEIWQSLGTLKLVHPSENSIAKVSTFAKLTGDYSVLSANDLHILALTYELEIKLNNGDWRLRKKPGDALDASKADVGTDGKQKLTEDNKKEEDSESVPKKKNKRRGGKKQKAKREAREAREAEN---------------------ANLELESKAEEHV---------------------EEAGSKEQICNDENIKESSDLNEVFEDADDDGDWITPENLTEAIIKDSGEDTTGSLGVEASEEDRHVALNRPENQVALATGDFAVQNVALQMNLNLMNFMSGLKIKRIRNYMLRCHACFKIFPLPKDGKPKHFCASCGGQGTLLRCAVSVDSRTGNVTPHLKSNFQWNNRGNRYSVASPLSKNSQKRYGKKGHVHSKPQENVILREDQKEYEKVIKQEEWTRRHNEKILNNWIGGGSADNYISPFAITGLKQHNVRIGKGRYVNSSKRRS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :: *: .:: . :: .:.. * *. *::: :.* : *:. .* : : *:* ****. **. *:::::***:** . * :*:::* :. . : : . . . :* . :: . .* : : * : . :: .: :. . *: . :: : * * ..: : : *. * *:*:*** *:.*:: . * ::. *.*:***:.*:* . . : ** ** : ** : :*::.. . . : . *:. . ::. : : .. . . :. :: . . :.. ** :.. .. . * ", "identical_positions": 58, "similar_positions": 133, "identity": "11.58%" }, { "cls_id": "homologset.agr.SGD:S000005583", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CX34-1", "uniprot_id": "SGT1_MOUSE", "id": "Q9CX34-1", "name": "Protein SGT1 homolog", "aln": "MAAAAAGPASSQRLFQSFSDALIDGDPQAALEELTKALEQNPDDAQYYCQRAYCHILLGK-YRDGIADVKKSLELNPNNCTALLRKG---------------ICEYHEKDYASALETFAEGQKLD--------------------------------STDTNFDTWIKRCQEIQNGSES----------EVSASQRTQSKIKYDWYQTESHVIITLMIKSVQKNDVRVGF-----SERELSALVKIP-AGEDYSLKLRLLHPIIPEQSTFKVLSTKIEIKMKKPEAVRWEKLEGQGDEPTP-----------KQFTADVKNMYPSSSHYTRNWDKLVGEIKEEEKNEKLEGDAALNKLFQQIYSDGSDEVKRAMNKSFMESGGTVLSTNWSDVGKRKVEINPPDDMEWKQY--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0BN85-1", "uniprot_id": "SGT1_RAT", "id": "B0BN85-1", "name": "Protein SGT1 homolog", "aln": "MAAAAAGPASSQRFFQSFPDALIDGDPQAALEELTKALEQNPDDAQYYCQRAYCHILLGK-YCDGIADVKKSLELNPNNSTALLRKG---------------ICEYYEKDYASALETFAEGQKLD--------------------------------GTDTNFDIWIKRCQEIQNGSEP----------EVSASQRTQSKIKYDWYQTESHVIITLMIKNVQKNDVRVDF-----SEKELSAVVKIP-SGEDCSLKLRLLHPIIPEQSTFKVLSTKIEIKMKKPEAVRWEKLEGQGDVPAP-----------KQFTADVKNMYPSSSHYTRNWDKLVGEIKEEEKNEKLEGDAALNKLFQQIYSDGSDEVKRAMNKSFMESGGTVLSTNWSDVGKRKVEINPPDDMEWKQY--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2Z0-1", "uniprot_id": "SGT1_HUMAN", "id": "Q9Y2Z0-1", "name": "Protein SGT1 homolog", "aln": "MAAAAAGTATSQRFFQSFSDALIDEDPQAALEELTKALEQKPDDAQYYCQRAYCHILLGN-YCVAVADAKKSLELNPNNSTAMLRKG---------------ICEYHEKNYAAALETFTEGQKLDIETGFHRVGQAGLQLLTSSDPPALDSQSAGITGADANFSVWIKRCQEAQNGSES----------EVWT---HQSKIKYDWYQTESQVVITLMIKNVQKNDVNVEF-----SEKELSALVKLP-SGEDYNLKLELLHPIIPEQSTFKVLSTKIEIKLKKPEAVRWEKLEGQGDVPTP-----------KQFVADVKNLYPSSSPYTRNWDKLVGEIKEEEKNEKLEGDAALNRLFQQIYSDGSDEVKRAMNKSFMESGGTVLSTNWSDVGKRKVEINPPDDMEWKKY--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHT3-1", "uniprot_id": "Q9VHT3_DROME", "id": "Q9VHT3-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVRHDWYQSETKVVITVLLKNAVDKNYAVEI-----TQK----RVHMT-ADG-YELDLKLLHPIVVERSSYKAFSTKVEITLAKETGIRWENLEEA------------------IVAAPVK-------PKAKNWDQLVSEEEKIDEKE-AKGEAALTNLFKKIYSSSSPEVQKAMNKSFSESGGTVLSTNWNEVGKERVTVKPPNGTEFREWEK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08446-1", "uniprot_id": "SGT1_YEAST", "id": "Q08446-1", "name": "Protein SGT1", "aln": "-------MPVEKDLKTAYKALYDEKEPLKALHLYDEILKGSPTNLTALIFKAACLEKLYFGFSDWHSDATMENAKELLDKALMTAEGRGDRSKIGLVNFRYFVHFFNIKDYELAQSYFKKAKNLG---------YVDDTLPLWEDRLETKLNKKNKKQKDSTNKHTIKPVESIENRGDNNSSHSPISPLKIETAPQESPKFKIDWYQSSTSVTISLFTVNLPESKEQVNIYISPNDRRTLSISYQVPKSGSEFQYNAKLSHEVDPKAVSLKIFPKKLEITLSKIDSTQWKKLEEDILTESSRLSDEGKNSDSATRLLSAETASKERLSYPSSSKKKIDWSKLDIDEEADEEAGSADSFFQKLYAGADPDTKRAMMKSFIESNGTALSTDWEDVSKGTVKTSPPEGMEPKHW--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: ****:.: * *::: . ... * : .: ::. :. . . .* * : : : * :..*:**.: * . :*::** .: . . .: :. : .:* : .: :*:::*:... :.::** *** **.**.***:*.:*.* * .**:. * :.: ", "identical_positions": 39, "similar_positions": 75, "identity": "9.44%" }, { "cls_id": "homologset.agr.SGD:S000005584", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6APJ5-1", "uniprot_id": "A0A8I6APJ5_RAT", "id": "A0A8I6APJ5-1", "name": "", "aln": "--------------------------------------------------------------------------------------MRRSEVLADESIVCLQKALTHLREIWGLIGIPEEQRLQRTEVVKKHIKDLLDKMIAEEENLRERLLKSISICRKELSTLCSELQVK---------------------------------------PFEEDK--EITVLQLEKDLRTQVELMRKQKKERKQELKLLQEQDQELREILCMPP------------------------------CDVDSTSVPTLEELNLFRQRVATLRETKESRHEQFVNIKRQIILCMEELEHTPDTSF-------------ERDVVCEDESAFCLSLENIATLQKLLKQLEVKKSQNEAECEGLRAQIRELWDRLQIPEEEREPVAAIMTGSKTKIRNALKLEVDRLEELKMQNIKQVIETIRVELAQFWDQCFYSQEQRQAFAP-YYSEDYTEN-------LLHLHDVEVIRLRNYYEAHKELFEGVQKWEESWKLFLEFERKASDPSRFTNRGGN--LLKEEKERAKLQKTLPKLEEELKARIEHWEQENSTAFVVNGQKFMEYVTEQWELHRLEKER----AKQERQLKNKRQTETEMLYGSAPRTPSKRPGQTPNKCGKV---------RKMNTTTMSTATPNSSIRPVFGGSVYRSPMSRLPPSGSKSVVTSLCSGKKTPRAARLRANKENLDLNGSILSGGYSGSTPLQRNCS--IKSVASTYSEFSKDPSLSDSSTVG--LQRELSKASRSDATSRILNSTNIQS--------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99K43-1", "uniprot_id": "PRC1_MOUSE", "id": "Q99K43-1", "name": "Protein regulator of cytokinesis 1", "aln": "--------------------------------------------------------------------------------------MRRSEVLADESITCLQKALTHLREIWELIGIPEEQRLQRTEVVKKHIKDLLDRMIAEEESLRERLLKSISICQKELSTLCSELQVK---------------------------------------PFQEEK--DTTILQLEKDLRTQVELMRKQKKERKQELKLLQEQEQELRDILCMPP------------------------------CDVDSTSVPTLEELKLFRQRVATLRETKESRREEFVNIKKQIILCMEELEHSPDTSF-------------ERDVVCEDESAFCLSLENIATLQKLLKQLEMKKSQNEAECEGLRTQIRELWDRLQIPEEEREPVEAIMTGSKTKIRNALKLEVDRLEELKMQNIKQVIEKIRVELAQFWDQCFYSQEQRQAFAP-YYSEDYTEN-------LLHLHDAEIVRLRNYYDVHKELFQGVQKWEESWKLFLEFERKASDPGRFTNRGGN--LLKEEKERAKLQKTLPKLEEELKARIEQWEQEHSTAFVVNGQKFMEYVTEQWELHRLEKER----AKQERQLKNKKQTEAEMLYGSTPRTPSKRPGQTPKKSG------------KMNTTTMSSATPNSSIRPVFGGSVYRSPMSRLPPSGSKSVVTSLCSGKKTPRAAQLRANKENLDLNGSILSGGYPGSTPLQHNCS--IKSVASTYSEFS----------------RELSKASRSDATSRILNSTNIQS--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43663-1", "uniprot_id": "PRC1_HUMAN", "id": "O43663-1", "name": "Protein regulator of cytokinesis 1", "aln": "--------------------------------------------------------------------------------------MRRSEVLAEESIVCLQKALNHLREIWELIGIPEDQRLQRTEVVKKHIKELLDMMIAEEESLKERLIKSISVCQKELNTLCSELHVE---------------------------------------PFQEEG--ETTILQLEKDLRTQVELMRKQKKERKQELKLLQEQDQELCEILCMPH------------------------------YDIDSASVPSLEELNQFRQHVTTLRETKASRREEFVSIKRQIILCMEALDHTPDTSF-------------ERDVVCEDEDAFCLSLENIATLQKLLRQLEMQKSQNEAVCEGLRTQIRELWDRLQIPEEEREAVATIMSGSKAKVRKALQLEVDRLEELKMQNMKKVIEAIRVELVQYWDQCFYSQEQRQAFAP-FCAEDYTES-------LLQLHDAEIVRLKNYYEVHKELFEGVQKWEETWRLFLEFERKASDPNRFTNRGGN--LLKEEKQRAKLQKMLPKLEEELKARIELWEQEHSKAFMVNGQKFMEYVAEQWEMHRLEKER----AKQERQLKNKKQTETEMLYGSAPRTPSKRRGLAPNTPGKA---------RKLNTTTMSNATANSSIRPIFGGTVYHSPVSRLPPSGSKPVAASTCSGKKTPRTGRHGANKENLELNGSILSGGYPGSAPLQRNFS--INSVASTYSEFAKDPSLSDSSTVG--LQRELSKASKSDATSGILNSTNIQS--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PAZ7-1", "uniprot_id": "A0A8M1PAZ7_DANRE", "id": "A0A8M1PAZ7-1", "name": "", "aln": "--------------------------------------------------------------------------------------MRKSEVIAAESVACLNKALCHLKDIWEEIGIPEDQRLERTNVVKNHVKGLLDMMIAEEESLRKRLMTSIEKCHKELSKLCLELQSP---------------------------------------PFQEEK--SGTMLQREKELRTHVEVMLKEKNQRMQALKALTEQDQDLCDLLCSQP------------------------------FSISPGCVPSMEQLENFHQHISCLTAEKERRHKEFVTLKKQIILCMDDLDQLPETSF-------------EKDVVCEDEESFCLSKENIDSLKVLLQQLENRKAENKRVCGSYREKILELWKRLQIPQEERDVISEHMTLSKKRNMEALQVEVKRLEELKLKNMQNVTETLRKEIAVYWEKCFYSADQRQAFMP-YYDDDFSEE-------LLSLHDAEIVQLKQYYEDHKELFEGVHKWEENWRLFIELEERAKDPSRFTNRGGN--LLKEEKQRADIVKGLPKLEKKLKAEIEQWELEQNREFQVNGQKFMQFVSDQWELYRLEKER----EKQERQLKKSKQTEEDMVYGTVIRTPTKRRFLGSTTPCKA---------RKLNP-TSSTGTSNSTIRSVIGGTVCHSPISRPPISASKGNGVKTPGHSKPPHQGLLERNKENICHLTGGVAGMTKVPASPQRNFS--INSVASTYSEFQ----------------RDLSKSSKSKHVPEILNSTIIQL--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N145-1", "uniprot_id": "A0A8M1N145_DANRE", "id": "A0A8M1N145-1", "name": "", "aln": "------------------------------------------------------------------------------------MTCRKSEALAFSLVTEINHAMARLVDIWDSIGIMEDQRVERMQTVKKHIDGLLHSMIMEEEALRHRIKTDIITFQKQLDTLCLELTLE---------------------------------------PFKLEE--KLTVLQMEKNLRCHVESLQKEKNERLREMNDFKKQDEELCVTLCADP------------------------------YYIPTGSVPSRTQLQELKEHVERLNKEKESRVKVFSGLREDIRNLMEELGHEPESSL-------------ERESICPDADIFLLTHDNIKALKLLLSQLEIKKESLISARDSLKERAMSLWNRLSCPESEAEVFQEPAMSTLSDDIRRWQRFVEHLEELQKAQLEEVINKVRQELVVLWDKCMFGPDQRQAFDVHFCDDQYTTE-------LLALHDSELLRMKIFYEEAQPILEDLEKWKRNWALFQEFERKAADPSRFSNRGGS--LLRETKERGKVQKLLPKLEEELRGRVEDWEIVKGLSFLVYGQRVMDYISSQWEEHRLQKDK----EKNER---MSKKTETPQFK-----TPTKR---------------------AHGMTCAATPTPN-KIR--------KTPSQLAPRSATVS-SISSASSSGSSTTFLCVPGRPQLSAKRTKTTETSTGPRLPLQDFNSDKKPVQMSYSAFT-------------------SEFSRKANGDAVLNSTVKDVL-------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZ62-1", "uniprot_id": "Q9VZ62_DROME", "id": "Q9VZ62-1", "name": "", "aln": "------------------------------------------------------------------------------------MNSPSAIAVKAQILEMTGEHVDQLHAMWSQL-FEVKTCGEFLLRLKDHANSFFTDLLNESREKQQAILNDIAALRAEATDLTRLLHEP---------------------------------------LDIGERPESMPLVVWELKLDKSIEHLRDQLARRRAEICELLLQQEQLCEELGELP------------------------------LPLLADPLPLPEEMDAFRNRLGQLRDQRVLRLKEMDQLRQAIKHDMKLLECLPQTDT-------------EERLLN--QVDHCLTPETFELLRNMQKNFADQVKELRERIDDMREKIHVLWDRLQETDEYAMRRVREATTYTQRTYDVLREELQRCQALRRQNLKTFIEQLRIEIKEMWDLTLKSQQERKRFSN-YYNDWYNED-------LLELHELELDDLKTFYNKNKEIFDLYESRAELWSRMEALEAKASEPNRFNNRGGQ--LLKEEKERKAITSKLPKIEQQITELVQAYEAQENTPFLVHGENILERMAADWERHRQAKQQS--SARKKAPPSASKIMPPPATGSTAPRTPRTLRNMSTLSSSTMSLRKTP---SQQHLRPLNITKSTGNLHKRLNPSGLQTGPKTPNAKRSLMNTLNSMKASPAKHLLAPSQQHNQLKSTKSPLKRVRVLDNTLRRSGGMGRRSIGTRSSKKAR---------------TKSNDQNAPPDSSDYTTDENPEQGVSYDEFQPTSRSSMLPRQRHQLAVPRTRRAEMNANLPVPRESLMIVQPRRQF---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZ61-1", "uniprot_id": "Q9VZ61_DROME", "id": "Q9VZ61-1", "name": "", "aln": "------------------------------------------------------------------------------------MLSS---EHKARILALTAEHFDELHAMWSRM-FEPQACEDCLARLKDHVHTFYTDLRKETSDKEQGILNDIAVLRNEASGLRRLLHKA---------------------------------------VDIGERPDDVPMEIWYIKLEKYIEQLRKELVSRRAEIRELLHQQQQLCDELGEQP------------------------------LSLLADPLPLPEEMDPFREHLAQLRDQRVQRLRDMDELRQNIKRNIKLLELQLRTDS-------------EKRLLN--ADNHKLTPYAYVRLQEMDKEFADQVQDLIDRIDEMRGKIECLWQRLRMTDEYAMRRVREATSYNQCTYDILREELERCQAMRQQNLIAFIEQLRIEINEWWDLSLKSTEERRRFTT-YYCDTQTED-------VLEQFEKELDNLKEFYNSNRKIFELYANRGELWTRMEALEAKANDPNRFNNRGGQ--LLKEEKERKTIMSRLPKIDQQITELVQVYMSETHTPFLVHGVDILERMSADWERHRQSKKQP--SAQKKDGSNTSGQMKPP----MVPLTPNTQKSNRGIHGSTSSLKKTP---TKANAS--TTAMSTGNLHKRRHPQHHNTNSPQP-AAAAKRNLIASLECNNASRKVCVNGQ----KLLKSPQRKVRVLEYSVRRGKGSGRPSTGSRNPQKIR---------------PIPKIHVRPPSGEE---NESPDE-----------------------------------------EAVVAI---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50275-1", "uniprot_id": "ASE1_YEAST", "id": "P50275-1", "name": "Anaphase spindle elongation protein", "aln": "METATSSPLPIKSRRNSENSGSTTVIPHMNPSLATPLTVSTMVNQSNSKEFMKLTPVRIRDFGSPLKNVSTNYHFLDSENGKGNTMDNMYRENFILISKDLEKLLENLNVIYQNIGYSNTEIITKEKIIFTTISNSIKQFFEQADEELKRLSAENGIEQDILNNILERINDPSGIKTIPDLYIRNAILLQESKTVPQSPKKPLSLLSKKAALDTAKKFVLGSFLPRLRDYLKSLITLKHLIQSVKENLPGLTEADNEAIAEFPELSTLTAYLLQIENGKGDIGLSMKFIIDNRKDILKGSAFKTINEESVKHMNEVIKIYEEEYERRFKSVLTKKVSISSICEQLGTPLATLIGEDFEQDLRSYGEEENSTSEIPNFHPVDRERMSKIDITLEKLQAIHKERADKKRLLMEQCQKLWTRLKISQEYIKTFMRNNSSLSTESLGRISKEVMRLEAMKKKLIKKLISDSWDKIQELWRTLQYSEESRSKFIIVFEELRNSATTLQEDELLLETCENELKRLEEKLTLYKPILKLISDFESLQEDQEFLERSSKDSSRLLSRNSHKILLTEEKMRKRITRHFPRVINDLRIKLEEADGLFDQPFLFKGKPLSEAIDIQQQEIEAKYPRCRVRMQRSKKGKCGANKENKVIKNTFKATESSIRVPIGLNLNDANITYKTPSKKTIQGLTKNDLSQENSLARHMQGTTKLSSPNRRATRLLAPTVISRNSKGNIERPTLNRNRSSDLSSSPRINHTHGEHAVKPRQLFPIPLNKVDTKGSHIPQLTKEKALELLKRSTGTTGKENVRSPERKSSLEDYAQKLSSPYKEPEHSIYKLSMSPEGKFQLNIQQKDIESGFDDTSMMEDENDKDFITWKNEQVSKLNGFSFTDI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .* :: : : : : . : . : : : . .. . : : . : : ::: : . .:. :.: : * . . : * . * : *. . : : :: . : ** ** .:. : : : :: : . . :: * . :.* * : . :* : *: :. : ::. . :* : :..*: .*.. ** * * * : :*:: :.: :: * . * . : : : : . : :.. * . .: : : . . . . ", "identical_positions": 26, "similar_positions": 115, "identity": "2.94%" }, { "cls_id": "homologset.agr.SGD:S000005585", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZQV8-1", "uniprot_id": "A0A8I5ZQV8_RAT", "id": "A0A8I5ZQV8-1", "name": "", "aln": "-MTEVQAMVEFSVELNKFYNVDLFQRGFYQIRASMKIPPRIPHRVEASLLHATGMTLAFPASVHDALVCSKTFQILYKNEEVVLNDVMIFKVKMLLDERK------IEETLEEISFLLSLDLHFTDGDYSADDLNALQLISSRTLKLHYSIYRGLHHHANIMFDYFHLSVVSVTVHASLVALHQPLISFPRPVKTTWLNRSAPAQSKDSAIPTLESVVFGVNYTKQLSPDGCTFLIAEPFLQHAYHFHYTLCATLLLAFKGLHSYFITVTEEIPSCQKLDLAKASMQVLYERLLRRAQPRTQNDTCLEAMDTEARLTELCEEVK-KVENPDELAELINMNLAQLCSLLMALWGQFLEAITLHEELRVLLAQEHHTLRVRRFSEAFFCFEHPREAAIAYQELHAQSHLQMCTAIKNTSFCSSLPPLPIECSELDGDLNSLPIIFEDRYLDSVIEDLDAPWMGIQSLQI-SEASKVDKHETEESSVAGLSSPELKVRPAVASSNCYTEGEKQLTKSLKGKNEESNKSKVKVTKLMKTMKPETTKKLIK----QNSKDSVVLVSYKCLKNTASSDLTKCFEGNPSYSQKEGLDPTMCRDNFDPKTYIRQPSQKEASSLSADTDRAEHKSPDTETMHPDQSALLNSGSLNLCANLSISGKLGISQDDSDIPDTEHKLASRSPSNDCLDCQTAPSSGVRTLEVKPSSEESFSEEKVTVKIGPWTELQEDELFVNNLLPDFEALDSNDKSKSIDLPLEKDALQEAKCRCTEESLTKFRSNLPAPSTKEYHVVVSGDTIKLPDSNAAYASSRFSDSGVESEPS-SFATHPNPEIAFETLQGPGPCNNERLLPQLLMKPDHNVKLSLGSHCTESTSALSEIQQSSLTSINSLPSDDELSPDDDCKRCAVADCQLSDSKTVLHPGTTSLPKWDDTKKSSVILQ---------QQCVVFSGHLDNDTLAMHSLDLSSEDPLQLILSGEDASSGVRSHWGSKPHLDTVFTGSQSHSTSSINSVETVPTLNSKLICLGSPCVVSGSVCTDAELSEDRTVEGKSSEPLNHKQICSEGPVVESHPLSTGDDSLSSSTDVVKQG--------LVEDYFGSQSNTDVSDACAVTYHSLVSSQ-ETCDKGIGDLQQEQGKEGMQD--DQEMVQNGYHEETDFPATGGAVSVHCVRADE-------------LGGQRHELSENLSSDYLRAAVTVPAVCTSACLSFPSAPRESPC-VKYSSRSKVDAITKQPS-SISYNFTSSTSWYENSPKPQIHAFLQAKEELK-QLKLPGFMYSDVPLLASSAPYFSMEEEE-GSEDGVHLIVCVHGLDGNSADLRLVKTYIELGLPGGRVDFLMSERNQNDTFADFDCMTDRLLDEIIQYIQIYSLTVSKISFIGHSLGNLIIRSVLTRPRFKYYLSKLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSNKAGLHYFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQSGQIYSEMIHNLLRPVLQSKGCNLVRYNVINALPNTADSLIGRAAHIAVLDSEIFLEKFFLVAALKYFQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NS59-1", "uniprot_id": "F135A_MOUSE", "id": "Q6NS59-1", "name": "Protein FAM135A", "aln": "-MTEVQAMVEFSVELNKFYNVDLFQRGFYQIRASMKIPARIPHRVEASLLHATGMTLAFPASVHDALVCSKTFQILYKNEEVVLNDVMIFKVKMLLDERK------IEETLEEISFLLSLGLHFTDGDYSADDLNALQLISSRTLKLHYSICRGLHHHANVMFDYFHLSVVSVTVHASLVALHQPLISFPRPVKTTWLNRNAPAQSKDSAIPTLESVVFGINYTKQLSPDGCSFLIAESFLHHAYHFHYTLCATLLLAFKGLHSYFITVTEEIPSCQKLD--------------------------LEEMDVEARLTELCEEVK-KVENPDELAELINMNLAQLCSLLMALWGQFLEAITLHEDLRVLLAQEHHTLRVRRFSEAFFCFEHPREAAIAYQELHAQSHLQMCTAIKNTSFCSSLPPLPIECSELDGDLNSLPIIFEDRYLDSVIEDLDAPWMGIQSLQI-SEASKTDKHETEESSVVGLSSPELKVRPAVASSNCYTEGEKQLTKSLKGKNEESNKSKVKVTKLMKTMKPENTKKLIK----QNSKDSVVLVSYKCLKTTASSDFTKCLEGSPSHSQKEGLDPTLCAGNFDPKTYTRQPSQKEASSLSANTDRSEHKSPDTENMQPDQFELLNSGSLNLCANLSISGKLAISQDNSDIPDTEHNLASTSSSNDCHDYQTTPSSGVRTLEVKSSSKESFNGEKITVKIGPWTELQEAELFVDNLLPDFEALDSNDKPKSIDIPLERDALQETKCHSTEESLTKFRSNLPAPSTKEYHVAVSSDTIKLPDTNATYASSRFSDSGVESEPS-SFATHPNPEIAFETLQGPGPCNNERLFPQLLMKPDHNVKFSLGSHCTESTSALSEIQ-SSLTSINSLPSDDELSPDDNCKKSAVPDCHLSDSKTVFNLGTMDLPKCDDTKKSSIILQ---------QQSVVFSGHLDNDTLAMHSLDLSTEDPLRLVFLDEDASSGVRSSWGSKPHLDAPFTGPQSQGTSSNNSTESVPTLNSKLICLGSPCVVSGSVCTDAGLSADRTVEGKSGEPLNHKQVCSAAPVVESDPLS-------SSTDVVKQG--------LVENYFGSQSTTDVSDACAITCHSPVSSQ-ETCDKGISDLQQEQGKEEEEE--DQEMVQNGYHEETDFSATDGTVSVHYISGNE-------------LGEGRHEQSEKLSSNYLSAGVTVPAVCTSGCLSFPSALRESPC-VKYSSRSKVDAITKQPS-SISYNFSSSTSWYENSPKPQIHAFLQAKEELK-QLRLPGFMYSDVPLLASSAPYFSMDEED-GSEDGVHLIVCVHGLDGNSADLRLVKTYIELGLPGGRVDFLMSERNQNDTFADFDCMTDRLLDEIIQYIQIYSLTVSKISFIGHSLGNLIIRSVLTRPRFKYYLSKLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSNKAGLHYFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQSGQIYSEMIHNLLRPVLQSKGCNLVRYNVINALPNTADSLIGRAAHIAVLDSEIFLEKFFLVAALKYFQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2D6-1", "uniprot_id": "F135A_HUMAN", "id": "Q9P2D6-1", "name": "Protein FAM135A", "aln": "-MTEVQAMVEFSVELNKFYNVDLFQRGFYQIRASMKIPSRIPHRVEASLLHATGMTLAFPASVHDSLICSKTFQILYKNEEVVLNDVMIFKVKMLLDERK------IEETLEEMNFLLSLDLHFTDGDYSADDLNALQLISSRTLKLHFSPHRGLHHHVNVMFDYFHLSVVSVTVHASLVALHQPLISFPRPVKTTWLNRNAPAQNKDSVIPTLESVVFGINYTKQLSPDGCSFIIADSFLHHAYRFHYTLCATLLLAFKGLHSYFITVTEEIPSCQKLE--------------------------LEEMDVEARLTELCEEVK-KIENPDELAELINMNLAQLCSLLMALWGQFLEVITLHEELRILLAQEHHTLRVRRFSEAFFCFEHPREAAIAYQELHAQSHLQMCTAIKNTSFCSSLPPLPIECSELDGDLNSLPIIFEDRYLDSVTEDLDAPWMGIQNLQR-SESSKMDKYETEESSVAGLSSPELKVRPAGASSIWYTEGEKQLTKSLKGKNEESNKSKVKVTKLMKTMKSENTKKLIK----QNSKDSVVLVGYKCLKSTASNDLIKCFEGNPSHSQKEGLDPTICGYNFDPKTYMRQTSQKEASCLPTNTERTEQKSPDIENVQPDQFDPLNSGNLNLCANLSISGKLDISQDDSEITQMEHNLASRRSSDDCHDHQTTPSLGVRTIEIKPSNKDPFSGENITVKLGPWTELRQEEILVDNLLPNFESLESNGKSKSIEITFEKEALQEAKCLSIGESLTKLRSNLPAPSTKEYHVVVSGDTIKLPDISATYASSRFSDSGVESEPS-SFATHPNTDLVFETVQGQGPCNSERLFPQLLMKPDYNVKFSLGNHCTESTSAISEIQ-SSLTSINSLPSDDELSPDENSKKSVVPECHLNDSKTVLNLGTTDLPKCDDTKKSSITLQ---------QQSVVFSGNLDNETVAIHSLNSSIKDPLQFVFSDEETSSDVKSSCSSKPNLDTMCKGFQSPDKS-NNSTGTAITLNSKLICLGTPCVISGSISSNTDVSEDRTMK-KNSDVLNLTQMYSEIPTVESETHLGTSDPFSASTDIVKQG--------LVENYFGSQSSTDISDTCAVSYSNALSPQKETSEKEISNLQQEQDKEDEEEEQDQQMVQNGYYEETDYSALDGTINAHYTSRDE-------------LMEERLTKSEKINSDYLRDGINMPTVCTSGCLSFPSAPRESPCNVKYSSKSKFDAITKQPS-STSYNFTSSISWYESSPKPQIQAFLQAKEELK-LLKLPGFMYSEVPLLASSVPYFSVEEED-GSEDGVHLIVCVHGLDGNSADLRLVKTYIELGLPGGRIDFLMSERNQNDTFADFDSMTDRLLDEIIQYIQIYSLTVSKISFIGHSLGNLIIRSVLTRPRFKYYLNKLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSNKAGLHYFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQSGQIYSEMIHNLLRPVLQSKDCNLVRYNVINALPNTADSLIGRAAHIAVLDSEIFLEKFFLVAALKYFQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z9L3-1", "uniprot_id": "A0A8M6Z9L3_DANRE", "id": "A0A8M6Z9L3-1", "name": "", "aln": "-MTEVQATVEFSVELHKFYNVDLFQRGFYQVRASMKVPPRIPQRVEASLLHPIGSDLAFPASVQDDVVCSKTFQILYKNEEIVVNDVFVFKVMMLLDAKKGVFLLQVEESLNEVDFQLCLDLFFTDGDYSPEEPSSLQSISSRTLRLHFSLHRGIHHHVNVMFDYFHLSVISATIHASLVALHQPLISFPRPVKSTWLNRNAPAQSKDSLIPPLETVVFGSTYVKQLSPDGKSFLVSDQCLQHAFSLHQNMCANLLRAYQSLFCYLTSLTKNLPASQRMELAKPSMQVLYERVLRRPYPPGQRHVYIEELDVEVRLHELCEQVKQKAESPDELAELVNMNLAQLCSLLMALWGNFLEVVSLNERVFVLLAQEHHTLRVQRFAEAFFCLEHPRQSALAYQELHAHSHQQMTTAIKSSSYFLSLPPLPVECADLDGDVNSLPIIFEDRYLESVTEDRDGPWLGLQNNRSGSVSAKADRSNSKDCIASGALGPYPDKQQASFATAWPEQ------------NEPSLKSKAKSIKLKKNTKTENSKKLIR----QSSKDSVVLTGYKNLKVPHSEKTIKSKDIDHQCNQRDELE--------DGGKFLLQNETTTTHCAQNAKDCTSGNLQGNATILSDGFPNLMSLQMQARPQAGTGAEAAAARVDP----------------------THPPAGLRHIDVKPSDKDPYQGDKVTVLLPHHPERTTKRDVPEITQTDFSEFKSR--------------------------------------VGDGATFVGPCGAALRNDNIPQASSRLSDSGIESEPSSATQLAPVSPSPFAPIGIEAPTELIPHRPPPLS-PASRGATALEGLNPESTSGVSGVQ-SSLTSINSLPSDDEVETEATSR------------------------------KSSILVQ---------EQSLIFSG-----------------ESQSLLLTNSRVLAQQKASHG---------DGMDS--------------------ALQSRCETS---------ASDRLVGSNETDLPGGPEACSEPQTAAQSSTS-----VTSSTDMVKKG--------FVENYFGSRSSTDISEISPLET-AAITLGIQTCP----NANDEEDEEEEQE---HEMIENGYYEET-----DGVVYVNGLPED----------------EGRCEDGGAEGRTLFYDHLGLEQLQET---YIPSAG-----------------IRTRPT-GPAP-TSSDLCWYKSAPTAQMTAFVQAKEELK-QLKLPGFLYSEVADLASTVPYFSMDEDE-NCDDGIHLIVCVHGLDGNSADLRLVKTYLELGLPGARIDFLMSERNQNDTFADFESMTDRLLDEIVQYIQIYNLTVSKISFVGHSLGNLIVRSVLTRPRFKCYLSRLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSKKAGLQFFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQTGPVYAEMIENLLLPVLQNKDCNLVRYDVIHALPNTANSLIGRAAHIAVLDSEIFLEKFFLVAGLKFFQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9DAI6-1", "uniprot_id": "F135B_MOUSE", "id": "Q9DAI6-1", "name": "Protein FAM135B", "aln": "-MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQSESSSLHSACVHESAVHSRVFQILYRNEEVSINDAMLFRVHLLLDGER------VEDALSEVEFQLKVDLHFTDSEQQLRDVTGTPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVAIHAALVALQQPLISFTRPGRGSWLGKGGPDTGPEQPTISLENLVFGAGYCKPTSSEGSFYVPSENCIQHAHKWHRDLCLLLLHAYQGLRLYFLVIMRDIPELPTME--------------------------LEALAVEETLSQLCSELQ-MLNNPEKIAEQISKDLAWLASHLMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEAFFYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVIFEDRYVDCPVSGHNLSVYPNFDVPVTSPAIMNLKGKE-KNLINQNSSSRKDIPLSTTEAPQLGSDEDVTRR-------PEVQENVSTWNPIDVCSESQVYLTIG--EFQNRAG---IPEDECWTGPRPDAVKDSLTDTDICSRSPGPD----EGQTPALTYIDVQSSNKY--CPRAELVQGINVQHEHRSSRESYGIVKTVPSK------VVAGTSQNNSTS-----------------------LNQTAALELRTLGRGVN-QDGKPVLLSLKLTPAEP-CDPPSTALREALDTKPSQPD-----------------------------------------HAEEPEDLSALSGVIKRSASIISDSGIESEPS-SVAWSEARSRALELP-------SDRDVLHQVVRRHAHHRNSLEGGHTESNTSLPSGIQASLSSISSLPFEEEERELALNKLTKSVSAPQISSPEESAEGADTI-KNTAGFSEDLDPS-----------SKENSPPRHTSLSYGGSRVQDVRAGHSLADIALDSDRPQGPGYMDIPNDKGNHPELQEP---CCLDGMAETPLHVETKGLNLKIPCTIVLENSKSRSFHRAAGETAKGKPEELSMS-------KCVLSNNS-----ISEVRAAS----------HHRVPEISCSPAVEAVNLNSTG--VQNSSLSVNDTMTLNRRHNASLEAKHEAGTVCPTVTHTIASQVSRNQELKTGTSISG-------------SHLN--STEAFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGLSSKQNPAPITHQPLGSFGVVSTYSSK-LEEEVSERMFSFYQAKEKFKKELKIEGFLYSDLSVLASDIPYFPPEEEEENLEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEKNQTDTFADFDTMTDRLLDEIIQHIQLYNLSISRISFIGHSLGNIIIRSVLTRPRFRYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFLYQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPLVEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFFLVAGLNYFK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LZ91-1", "uniprot_id": "F1LZ91_RAT", "id": "F1LZ91-1", "name": "", "aln": "-MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQTESSSLHSACVHESVVHSRIFQILYRNEEVSINDAMLFRVHLLLDGER------VEDALSEVEFQLKVDLHYTDSEQQLRDVTGTPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVAIHAALVALQQPLISFTRPGRGSWLGKGGPDTGPEQPTISLENLVFGAGYCKPTTSEGSFYVPSENCIQHAHKWHRDVCLLLLHAYRGLRLYFLVIMRDIPELPTME--------------------------LEVLAVEETLSQLCSELQ-MLNNPEKIAEQISKDLAWLASHLMALWTQFLDTVTLHSHVTTYLTQEHHTLRVRRFSEAFFYMEHQKLAVLTFQENLIQTHSQLSMDIRNSEYLTSMPPLPAECLDIDGDWNTLPVIFEDRYVDCPVSGHNLSVYPNFEVPVTSPAIMKLKGKE-KSVINQKSSSRKEAPLSTTEAPELGSDEDVIQC-------PEMEENVSTQNPMDVCSESQVYLSIG--EFQNRAG---IPEDECWTGPRPDAVKDSLTDVDICRRSPGPE----EGHTPALTYIDVESSNKN--YPRAEPVLGLNVQHEPRGSRDSYGIVKTMPSK------VLAGISQNNSIS-----------------------VNQTAALELRTLGRGVG-QEGKPVLLSLKLTPAEP-CDPLSTGLREALDTKPSLPD-----------------------------------------PGEEPEDLSVLSGVIKRSASIISDSGIESEPS-SVAWSEARSRALEIP-------SDRDILHQVVRRHAHHRNSLEGGHTESNTSLPSAIQASLSSISSLPFEDEERELALTKLTKSVSAPQISSPEDTAEDSDTI-KNTAGFSEDLDLS-----------SKDNSSSRYSSPSYSGSRVQDVRAGHSLADIAVASDRPQGPGYMDIHKGNENHPDLQGP---CCLDAMAENIPHVETKGLNLKIPCTTVLENPKTRSFHRTAVETAKGKAKELSLS-------KHMLSNNS-----ISEVRAAS----------HHRVPEISCAPAVGAGHLHSTG--VQNGSLSVNDTMTLNRRHNASPEAKHEAGTVCPTVTHTIASPVSRNQELKAGTSISG-------------SHLN--STEAFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGLSSKQSPAPITHQPLGSFGVVSTYSSE-LEEEVSERMFSFYQAKEKFKKELKIEGFLYSDLSVLASDIPYFPPEEEEENLEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEKNQMDTFADFDTMTDRLLDEIIQHIQLYNLSISRISFIGHSLGNIIIRSVLTRPRFRYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFLYQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPLVEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFFLVAGLNYFK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q49AJ0-1", "uniprot_id": "F135B_HUMAN", "id": "Q49AJ0-1", "name": "Protein FAM135B", "aln": "-MSEIQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESSSLHSACVHDSTVHSRVFQILYRNEEVPINDAVVFRVHLLLGGER------MEDALSEVDFQLKVDLHFTDSEQQLRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTVHAALVALQQPLISFTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSSEGSFYITSENCMQHAHKWHRDLCLLLLHAYRGLRLHFLVIMRDIPELPHTE--------------------------LEALAVEETLSQLCSELQ-MLNNPEKIAEQISKDLAWLTSHMMTLWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEAFFYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVIFEDRYVDCPATGHNLSVYPNFDVPVTSPTIMNLKDKEDNCMVNSNLSFREDLVLSTIKPSQMDSDEEVIRC-------PEPGENVATQNHMDMCSESQVYISIG--EFQNKAG---VPEDECWTGQTSDAGTYPVADVDTSRRSPGPE----DGQAPVLTYIDVKSSNKN--PSRAEPLVAFNAQHESRSSRDKYGLDRTGLSK------VVVGGSHQNAIS-----------------------SDKTTLHELSTLGKGID-QEGKMVLLSLKLTPSEP-CDPLSSTLREPLDIRSSLKDS----------------------------------------HTEEQEELSVLSGVIKRSSSIISDSGIESEPS-SVAWSEARSRALELP-------SDREVLHPFVRRHALHRNSLEGGHTESNTSLPSGIQASLTSISSLPFEEDEREVALTKLTKSVSAPHISSPEEAAEDADTK-QQDGGFAEPSDMH-----------SKSQGSPGSCSQLCGDS-GTDAGADHPLVEIVLDADNQQGPGYIDIPKGKGKQFDAQGH---CLPDGRTENTPGVETKGLNLKIPRVIALENPRTRSLHRALEETPKGMPKDLNVG-------QQALSNSG-----ISEVEGLS----------QHQVPELSCTSAADAINRNSTGQQSQSGSPCIMDDTAFNRGVNAFPEAKHKAGTVCPTVTHSVHSQVLKNQELKAGTSIMG-------------SHLT--SAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQTLFPITHQPLGSFGVVSTHSST-LDEEVSERMFSFYQAKEKFKKELKIEGFLYSDLTVLASDIPYFPPEEEEENLEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEKNQMDTFADFDTMTDRLLDEIIQHIQLYNLSISRISFIGHSLGNIIIRSVLTRPRFRYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFLYQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPLVEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFFLVAGLNYFK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PSQ6-1", "uniprot_id": "A0A8M1PSQ6_DANRE", "id": "A0A8M1PSQ6-1", "name": "", "aln": "MMSEVQGTVEFSLELHKFHNVDLFQRGFYQVRAGLRVSPRVPHRITATTPGYTGECSFSNAGVHDGGVFSRIFQILYRNEEVTLEDHINFRLHLLLDGER------VEEAVSEVDVQLKLDLHFTDNEQQLADISSVPVISSRTLGLHFHPQQGLHHHLPVMFDYFHLSVISVSIHASLVALHQPLISFARSGKGTWLGKGSPESEAPPSAMSVENLMFGAGYCKPVPTEGSFYVPSENCLQRAYTWHRRICKLLLAAHRALRSYYTTLMKEIPQLQHIQ--------------------------TEDLPLEETLNQLTIELQ-LQSGHEKVAEQISKDLTQLCAQLSALWTQFLESTVPNPYIRSYLAQEHHTLRVRRFSEAYFFTEHPKESSLTFQEELINRHAQVSTEMRNSDYLLRMPPLPVECLDIDGDWSSLPIIFEDRYVDTPCLDYNVVHEQNQAVLNSQPCFEPTRVKGQTASPAEKTQDTSLPATSPEEPPSEDCTEMPTYMTLTDHQDDDVTEHIKPRPQAETLTDHVEEADIDGCEFITTSSNSRIHSVDEVTCQYENDGNTMSVDTDDVIDNQEKT----SCQKEAANESDHTSSQQTNVFNSGQPLLLVPTDLGELPDLTSLGSFEFLPTYNHDDNLETPGDTGSPDNQ-----------------------EPQTVFDNRHIQAPAKD-YGGKDTSPGILLKATLPGTDPLVTSPSRNVIHQIRRLS-----------------------------------------ETPPRGVFLGGAKLMNRSSSVISDSGIESEPS-SVAWTLEGRGVVAG---------GRDILQSLARCRTAHQSSLEGLQTESHGSLPSATQASLTSISSLPYEEEE-DRQLNTLTKSASAPQISSPDDTEEDRETPNQETRTVCEANQVTGTRCEANPMRQNKESANEVKRNLQMEETTQQDTTNVLVANHIRDEAANEVKQTLQEVTREDGNTTTNQEKRNVCVANQLRK--SEVAANEVKQNLQGVFREDGNETSNQEIDIEESSNQDITDLTFVNPEMLLYQQFLMDSGK-DATLEELTENSKDFQGNILLKEYLMDESTEICRCEDEYCEHKRKLESNQYHKDADDISVCHIHLNELEVASMENLPEPTTNDKRTHGIAANEKERPADPIEPPTNERDQQILEGQSRINKVPSTGLAFVNKKVVEVVNLSVSCAPTCLPFSSVLRDSPSVSGISTRQATSPITHQPLGSFGIISSNSFFGADQEINERMINFFKAKEALLRELVFRGTLYSDLPYLASEHPYFPPEEDDTEFEDGIHLVVCVHGLDGNSADLRLVKTFVELGLPGSRLDFLMSERNQTDTFADFDTMTDRLLDEIIQHIQLYNLTIHRISFIGHSLGNVIIRSVLTRPRFRCYLCKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDHTDPRQTFLYTLSKKPGLQFFKNVVLVASPQDRYVPFHSARIEMCRTALKDRTTGPVYTEMINNLLQPLLSAPNCRLIRQNVFHALPNTANTLIGRAAHIAVLDSELFLEKFLLVAGLNYFK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08448-1", "uniprot_id": "LPL1_YEAST", "id": "Q08448-1", "name": "Lipid droplet phospholipase 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MTSDKHLFVLIHGLWGNYTHMESMRTILSTTLKKEDVNDDMIYFLPKQNAMFKTFDG-------------IEIIGYRTLIEVCEFIRDYK-DGKITKLSVMGYSQGGLVARFMIGKMLTEFKEL--------------------------------------------FEDIEPQLFITMATPHLG---------VEFYNPTGIAYKSALYSALRTLGSTILGKSGREMFIANSSNNILVKLSQGEYLEALSLFKWRIAFAN------------VKNDRTVAFYTAFITDCDPFIDFDNKLKYTFEEKIPGSGYKG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILPKIVDLNALN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VNSHAPTKPTKTYKKWGRTILIILVATFLILP-------------IALVMNGLG-------------------TAYSYIVTCKYR-------KMLSNGILHNEVR--GKLGLTEQLKGYVTDAYGSIINSALDMDANYEASNSNLVNEEELP---WKEFIQKYTTINDGVWKSKFKKLP----------FDENRKVILRNLN---KLKWIRVPIYIKAVN-----AHGVIVARRGMDENTAATGIACIEFTAQLLAYLMHKSN------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.: * : * : : * : :: . :: :: : :: :. ..:: : : :* : :. : :* .: * * : : : .: .* . : : : : . : :::. :.: *: :: ::: : ::. ..: :* : . ..* **:: . :* ::: : : *.: :. : : ::**. .:::: : : . ::: :*.: :: .*: .:: .: *.:* :: ..:. .* . .*. : :. : :. *:* : * . : *: :* *. *:::: : : : : *.. : : :* *: :** :: . ", "identical_positions": 36, "similar_positions": 154, "identity": "2.26%" }, { "cls_id": "homologset.agr.SGD:S000005587", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54833-1", "uniprot_id": "CSK22_MOUSE", "id": "O54833-1", "name": "Casein kinase II subunit alpha'", "aln": "----------------MPGPAAGSRARVYAEVNSLR-----SREYWDYEAHVP------------------------------SWG-------------------------------------------------------------NQDDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGTDELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCAEN-------TVLSSGLTAAR--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FH41-1", "uniprot_id": "F7FH41_RAT", "id": "F7FH41-1", "name": "Casein kinase II subunit alpha", "aln": "VSSASSSSLFAAAAAAAPLPAGGCRCRCRCRHHRLWGPRAERRPPRSTNPAVPPAAEGPGPAWPAPPAPPARASVRPPAPAGPAWRGRPPPPRSSSCSGGPRPAASRACRPALRAAPPPPSAPRGAPRSRPPCPARPRAVGPGSTPSNQDDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGTDDLYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCAEN-------TVLSSGLTAAR--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19784-1", "uniprot_id": "CSK22_HUMAN", "id": "P19784-1", "name": "Casein kinase II subunit alpha'", "aln": "----------------MPGPAAGSRARVYAEVNSLR-----SREYWDYEAHVP------------------------------SWG-------------------------------------------------------------NQDDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADN-------AVLSSGLTAAR--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P68400-1", "uniprot_id": "CSK21_HUMAN", "id": "P68400-1", "name": "Casein kinase II subunit alpha", "aln": "-----------------MSGPVPSRARVYTDVNTHR-----PREYWDYESHVV------------------------------EWG-------------------------------------------------------------NQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSS-MPGGSTPVSSANMMSG--ISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NEV1-1", "uniprot_id": "CSK23_HUMAN", "id": "Q8NEV1-1", "name": "Casein kinase II subunit alpha 3", "aln": "-----------------MSGPVPSRARVYTDVNTHR-----PREYWDYESHVV------------------------------EWG-------------------------------------------------------------NQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWRLGCMLASMIFRKEPFFHGRDNYDQLVRIAKFLGTEDLYGYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSS-MPGGSTPVSSANVMSG--ISSVPTPSPLGPLAGSPVIAAANPLGMPVPAATGAQQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60737-1", "uniprot_id": "CSK21_MOUSE", "id": "Q60737-1", "name": "Casein kinase II subunit alpha", "aln": "-----------------MSGPVPSRARVYTDVNTHR-----PREYWDYESHVV------------------------------EWG-------------------------------------------------------------NQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMSSTS-MAGGSTPVSSANMMSG--ISSVPTPSPLGPLAGSPVIAAANSLGIPVPAAAGAQQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19139-1", "uniprot_id": "CSK21_RAT", "id": "P19139-1", "name": "Casein kinase II subunit alpha", "aln": "-----------------MSGPVPSRARVYTDVNTHR-----PREYWDYESHVV------------------------------EWG-------------------------------------------------------------NQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMSSAG-MAGGSTPVSSANMMSG--ISSVPTPSPLGPLAGSPVIAAANSLGIPVPAAAGAQQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2B6B1-1", "uniprot_id": "A0A8M2B6B1_DANRE", "id": "A0A8M2B6B1-1", "name": "non-specific serine/threonine protein kinase", "aln": "-----------------MSGPVTSRSRVYPDVNTQR-----PREYWDYESHVV------------------------------EWG-------------------------------------------------------------NQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLLDIIKDPVSRTPALVFEHVNNTDFKQLYQTLSDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPSQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSTEALDFLDKLLRYDHQARLTAREAMEHPYFYPIVKDQARMGSTSGLSTGSTPVSTSSMITAGGVTSLSSSQPMANMAGSPVISSPSALATQVPAAAGAQP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08181-1", "uniprot_id": "CSK2A_DROME", "id": "P08181-1", "name": "Casein kinase II subunit alpha", "aln": "-----------------MT--LPSAARVYTDVNAHK-----PDEYWDYENYVV------------------------------DWG-------------------------------------------------------------NQDDYQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKKKKIKREIKILENLRGGTNIITLLAVVKDPVSRTPALIFEHVNNTDFKQLYQTLTDYEIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEELYAYLDKYNIDLDPRFHDILQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHPYFLPIVNGQMNPNNQQ--------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P19454-1", "uniprot_id": "CSK22_YEAST", "id": "P19454-1", "name": "Casein kinase II subunit alpha'", "aln": "-------MPLPPSTLNQKSNRVYSVARVYKNACEER-----PQEYWDYEQGVT-----------------------------IDWG-------------------------------------------------------------KISNYEIINKIGRGKYSEVFSGRCIVNNQKCVIKVLKPVKMKKIYRELKILTNLTGGPNVVGLYDIVQDADSKIPALIFEEIKNVDFRTLYPTFKLPDIQYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLAEFYHPGVDYNVRVASRYHKGPELLVNLNQYDYSLDLWSVGCMLAAIVFKKEPFFKGSSNPDQLVKIATVLGTKELLGYLGKYGLHLPSEYDNIMRDFTKKSWTHFITSET-KLAVPEVVDLIDNLLRYDHQERLTAKEAMDHKFFKTKFE-----------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .* . : * * : .:*:::.*:*********.. *...:: *:*:***** *** **:*** ** **.*:: * ::*. *: ***:** ::*.**: ** :. :*::*: ::* ******* *********:***** .:***************. :*********.*******: : ******:* :*****:::*::****:* .* ****:**..***.:* *: ** :.* ..:.:*: .::* * .*: *:. :*. .*.:*::*:****** ****:*** * :* . .: ", "identical_positions": 160, "similar_positions": 93, "identity": "31.56%" }, { "cls_id": "homologset.agr.SGD:S000005589", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P21531-1", "uniprot_id": "RL3_RAT", "id": "P21531-1", "name": "Large ribosomal subunit protein uL3", "aln": "MSHRKFSAPRHGSLGFLPRKRSSRHRGKVKSFPKDDPSKPVHLTAFLGYKAGMTHIVREVDRPGSKVNKKEVVEAVTIVETPPMVVVGIVGYVETPRGLRTFKTVFAEHISDECKRRFYKNWHKSKKKAFTKYCKKWQDDTGKKQLEKDFNSMKKYCQVIRIIAHTQMRLLPLRQKKAHLMEIQVNGGTVAEKLDWARERLEQQVPVNQVFGQDEMIDVIGVTKGKGYKGVTSRWHTKKLPRKTHRGLRKVACIGAWHPARVAFSVARAGQKGYHHRTEINKKIYKIGQGYLIKDGKLIKNNASTDYDLSDKSINPLGGFVHYGEVTNDFIMLKGCVVGTKKRVLTLRKSLLVQTKRRALEKIDLKFIDTTSKFGHGRFQTMEEKKAFMGPLKKDRIAKEEGA-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P27659-1", "uniprot_id": "RL3_MOUSE", "id": "P27659-1", "name": "Large ribosomal subunit protein uL3", "aln": "MSHRKFSAPRHGSLGFLPRKRSSRHRGKVKSFPKDDASKPVHLTAFLGYKAGMTHIVREVDRPGSKVNKKEVVEAVTIVETPPMVVVGIVGYVETPRGLRTFKTVFAEHISDECKRRFYKNWHKSKKKAFTKYCKKWQDDTGKKQLEKDFNSMKKYCQVIRIIAHTQMRLLPLRQKKAHLMEIQVNGGTVAEKLDWARERLEQQVPVNQVFGQDEMIDVIGVTKGKGYKGVTSRWHTKKLPRKTHRGLRKVACIGAWHPARVAFSVARAGQKGYHHRTEINKKIYKIGQGYLIKDGKLIKNNASTDYDLSDKSINPLGGFVHYGEVTNDFIMLKGCVVGTKKRVLTLRKSLLVQTKRRALEKIDLKFIDTTSKFGHGRFQTMEEKKAFMGPLKKDRIAKEEGA-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P39023-1", "uniprot_id": "RL3_HUMAN", "id": "P39023-1", "name": "Large ribosomal subunit protein uL3", "aln": "MSHRKFSAPRHGSLGFLPRKRSSRHRGKVKSFPKDDPSKPVHLTAFLGYKAGMTHIVREVDRPGSKVNKKEVVEAVTIVETPPMVVVGIVGYVETPRGLRTFKTVFAEHISDECKRRFYKNWHKSKKKAFTKYCKKWQDEDGKKQLEKDFSSMKKYCQVIRVIAHTQMRLLPLRQKKAHLMEIQVNGGTVAEKLDWARERLEQQVPVNQVFGQDEMIDVIGVTKGKGYKGVTSRWHTKKLPRKTHRGLRKVACIGAWHPARVAFSVARAGQKGYHHRTEINKKIYKIGQGYLIKDGKLIKNNASTDYDLSDKSINPLGGFVHYGEVTNDFVMLKGCVVGTKKRVLTLRKSLLVQTKRRALEKIDLKFIDTTSKFGHGRFQTMEEKKAFMGPLKKDRIAKEEGA-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9PWZ3-1", "uniprot_id": "RL3L_MOUSE", "id": "E9PWZ3-1", "name": "Large ribosomal subunit protein uL3-like", "aln": "MSHRKFSAPRHGHLGFLPHKRSRRHRGKVKSWPRDDPSQPVHLTAFLGYKAGMTHTLREVHRPGLKISKREEVEAVTIVETPPLVVVGVVGYVATPRGLRSFKTIFAEHLSDECRRRFYKDWHKSKKKAFTKACKRWRDADGKKQLQKDFAAMKKYCKVIRVIVHTQMKLLPFRQKKAHIMEIQLNGGTVAEKVAWVQARMEKQVPVHSVFSQSEVIDVIAVTKGRGVKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPARVGCSIARAGQKGYHHRTELNKKIYRIGRGLHMEDGKMVRNNASTSYDVTDKSITPLGGFPHYGEVNNDFIMLKGCIAGTKKRVITLRKSLLVHHSRRALENIELKFIDTTSKFGHGCFQTAQEKRAFMGPQKK-HLEKEKPETLGNM--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A9G1-1", "uniprot_id": "D4A9G1_RAT", "id": "D4A9G1-1", "name": "60S ribosomal protein L3-like", "aln": "MSHRKFSAPRHGHLGFLPHKRSRRHRGKVKSWPRDDPSQPVHLTAFLGYKAGMTHTLREVHRPGLKISKREEVEAVTIVETPPLVVVGVVGYVATPRGLRSFKTIFAEHLSDECRRRFYKDWHKSKKKAFTKACKRWRDADGKKQLQKDFAAMKKYCKVIRVIVHTQMKLLPFRQKKAHIMEIQLNGGTVAEKVAWAQARLEKQVPVHSVFSQSEVIDVIAVTKGRGVKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPARVGCSIARAGQKGYHHRTELNKKIYRIGRGLHMEDGKMVRNNASTSYDVTDKSITPLGGFPHYGEVNNDFVMLKGCIAGTKKRVITLRKSLLVHHSRRALENIELKFIDTTSKFGHGCFQTAQEKRAFMGPQKK-HLEKEKPETSGNV--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92901-1", "uniprot_id": "RL3L_HUMAN", "id": "Q92901-1", "name": "Ribosomal protein uL3-like", "aln": "MSHRKFSAPRHGHLGFLPHKRSHRHRGKVKTWPRDDPSQPVHLTAFLGYKAGMTHTLREVHRPGLKISKREEVEAVTIVETPPLVVVGVVGYVATPRGLRSFKTIFAEHLSDECRRRFYKDWHKSKKKAFTKACKRWRDTDGKKQLQKDFAAMKKYCKVIRVIVHTQMKLLPFRQKKAHIMEIQLNGGTVAEKVAWAQARLEKQVPVHSVFSQSEVIDVIAVTKGRGVKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPARVGCSIARAGQKGYHHRTELNKKIFRIGRGPHMEDGKLVKNNASTSYDVTAKSITPLGGFPHYGEVNNDFVMLKGCIAGTKKRVITLRKSLLVHHSRQAVENIELKFIDTTSKFGHGRFQTAQEKRAFMGPQKK-HLEKETPETSGDL--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O16797-1", "uniprot_id": "RL3_DROME", "id": "O16797-1", "name": "Large ribosomal subunit protein uL3", "aln": "MSHRKFSAPRHGSMAFYPKKRSARHRGKVKAFPKDDASKPVHLTCFIGYKAGMTHIVREADRPGSKINKKEVVEAVTVLETPPMIVVGAVGYIETPFGLRALVNVWAQHLSEECRRRFYKNWYKSKKKAFTKASKKWTDDLGKKSIENDFRKMLRYCKVIRVIAHSQIRLIKQRQKKAHVMEIQLNGGSIEDKVKWAREHLEKPIQVSNVFGQDEMIDCVGVTKGKGFKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPSRVSTTVARAGQKGYHHRTEINKKIYRIGAGIHTKDGKVIKNNASTEYDLTDKSITPMGGFPHYGEVNNDFVMIKGCCIGSKKRIITLRKSLLKHTKRSALEQIKLKFIDTSSKMGHGRFQTPADKLAFMGPLKKDRLKEEAAATTAAAAAATTTSA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14126-1", "uniprot_id": "RL3_YEAST", "id": "P14126-1", "name": "Large ribosomal subunit protein uL3", "aln": "MSHRKYEAPRHGHLGFLPRKRAASIRARVKAFPKDDRSKPVALTSFLGYKAGMTTIVRDLDRPGSKFHKREVVEAVTVVDTPPVVVVGVVGYVETPRGLRSLTTVWAEHLSDEVKRRFYKNWYKSKKKAFTKYSAKYAQDGAG--IERELARIKKYASVVRVLVHTQIRKTPLAQKKAHLAEIQLNGGSISEKVDWAREHFEKTVAVDSVFEQNEMIDAIAVTKGHGFEGVTHRWGTKKLPRKTHRGLRKVACIGAWHPAHVMWSVARAGQRGYHSRTSINHKIYRVGKG---DD----EANGATSFDRTKKTITPMGGFVHYGEIKNDFIMVKGCIPGNRKRIVTLRKSLYTNTSRKALEEVSLKWIDTASKFGKGRFQTPAEKHAFMGTLKKDL--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:.***** :.* *:**: *.:**::*:** *:** **.*:******* :*: .*** *. *:* *****:::***::*** ***: ** ***:: .::*:*:*:* :*****:*:********* . :: : . ::.:: : :*..*:*::.*:*:: *****: ***:***:: :*: *.: ::*: : * .** *.*:** :.****:* :*** ** *********:*************::* ::*****:*** **.:*:**:::* * .* . *.:*.:* : *:*.*:*** ****:.***:*:*** *.:**::****** : .* *:*::.**:***:**:*:* *** :* ****. ** ", "identical_positions": 204, "similar_positions": 118, "identity": "49.04%" }, { "cls_id": "homologset.agr.SGD:S000005590", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UNL4-1", "uniprot_id": "ING4_HUMAN", "id": "Q9UNL4-1", "name": "Inhibitor of growth protein 4", "aln": "---------------------MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADL-KEKQIESSDYDSS----SSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQERKKK---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8WYH8-1", "uniprot_id": "ING5_HUMAN", "id": "Q8WYH8-1", "name": "Inhibitor of growth protein 5", "aln": "---------------------MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQRVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADL-KDK-MEGSDFESS----GGRGLKKGRGQKEKRGSRGRGR-RTSEEDTPKKKKHK-----GGSEF---TDTILSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCVQEKRKKK--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9H160-1", "uniprot_id": "ING2_HUMAN", "id": "Q9H160-1", "name": "Inhibitor of growth protein 2", "aln": "MLGQQQQQLYSSAALLTGERSRLLTCYVQDYLECVESLPHDMQRNVSVLRELDNKYQETLKEIDDVYEKYK---KEDDLNQKKRLQQLLQRALINSQELGDEKIQIVTQMLELVENRARQMELHSQCFQDPAESERASDKAKMDSSQPERSSRRPRRQRTSESRDLCHMANGIEDCDDQPPKEKKSK-------SAKKKKRSKAKQEREASPVEFAIDPNEPTYCLCNQVSYGEMIGCDNEQCPIEWFHFSCVSLTYKPKGKWYCPKCRGDNEKTMDKSTEKTKKDRRSR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08465-1", "uniprot_id": "YNG1_YEAST", "id": "Q08465-1", "name": "Protein YNG1", "aln": "--------------MEHLANENSDSDIRYSFLSTLDHLPCELIRSLRLMQTIDLFKNE--------------------------------EDEPGMERACRDLLLVATYINDLVDDQIHFLKQHKKELEIQK-----SVTKNFNSS-----LENIKSKLTLEEPGAYKEPKLLLKINLKKAKSRERK----------ESITSPTIGINQGDVTEGNNNQEE-VYCFCRNVSYGPMVACDNPACPFEWFHYGCVGLKQAPKGKWYCSKDCKEIANQRSKSKRQKRRK----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. :: ** :: *.. ::: :* :: . :. : : :. ::*:.: : :. . :: . :** . : :. : : . .* : * . .. : : :* .**:*.:**** *:.*** *.:****:.**.*. *:***:*.: : : ", "identical_positions": 35, "similar_positions": 67, "identity": "12.07%" }, { "cls_id": "homologset.agr.SGD:S000005591", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFQ8-1", "uniprot_id": "D3ZFQ8_RAT", "id": "D3ZFQ8-1", "name": "Cytochrome c1, heme protein, mitochondrial", "aln": "MAAAAAASLRRSVLGPRGMGLPGASAPGLLGGARPRHLPLRTPQAVSLSSKSGPSRGRKVMLSALGMLAAGGAGLAVA---LHSAVSASDLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVCSSCHSMDYVAYRHLVGVCYTEEEAKALAEEVEVQDGPNEDGNMFMRPGKLSDYFPKPYPNPEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGY-CEPPTGVSLREGLYFNPYFPGQAIGMAPPIYTEVLEYDDG-TPATMSQVAKDVATFLRWASEPEHDHRKRMGLKMLLMMGLLLPLTYAMKRHKWSVLKSRKLAYRPPK----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0M3-1", "uniprot_id": "CY1_MOUSE", "id": "Q9D0M3-1", "name": "Cytochrome c1, heme protein, mitochondrial", "aln": "-MAAAAASLRRTVLGPRGVGLPGASAPGLLGGARSRQLPLRTPQAVSLSSKSGPSRGRKVMLSALGMLAAGGAGLAVA---LHSAVSASDLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVCSSCHSMDYVAYRHLVGVCYTEEEAKALAEEVEVQDGPNDDGEMFMRPGKLSDYFPKPYPNPEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGY-CEPPTGVSLREGLYFNPYFPGQAIGMAPPIYTEVLEYDDG-TPATMSQVAKDVATFLRWASEPEHDHRKRMGLKMLLMMGLLLPLTYAMKRHKWSVLKSRKLAYRPPK----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08574-1", "uniprot_id": "CY1_HUMAN", "id": "P08574-1", "name": "Cytochrome c1, heme protein, mitochondrial", "aln": "-MAAAAASLRGVVLGPRGAGLPGARARGLLCSARPGQLPLRTPQAVALSSKSGLSRGRKVMLSALGMLAAGGAGLAMA---LHSAVSASDLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVCASCHSMDFVAYRHLVGVCYTEDEAKELAAEVEVQDGPNEDGEMFMRPGKLFDYFPKPYPNSEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGY-CEPPTGVSLREGLYFNPYFPGQAIAMAPPIYTDVLEFDDG-TPATMSQIAKDVCTFLRWASEPEHDHRKRMGLKMLMMMALLVPLVYTIKRHKWSVLKSRKLAYRPPK----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRL0-1", "uniprot_id": "Q9VRL0_DROME", "id": "Q9VRL0-1", "name": "Cytochrome c1, heme protein, mitochondrial", "aln": "-MAATLRRFHG--LRLLKS-APALSLQ----------------QAKNLSSAGSWASGNKKLIGALGAITGGVGALIYA---LEQSVQASGGEVHSPAQLWNHKGLFDALDHQSVRRGYEVYKQVCSACHSMQYIAYRNLVGVTHTEAEAKAEAEQITVKDGPDDTGNYYTRPGKLSDYFPSPYPNEEAARAANNGAYPPDLSYIVSARKGGEDYIFSLLTGY-HDAPAGVVLREGQYFNPYFPGGAISMAQVLYNEVIEYEDG-TPPTQSQLAKDVATFLKWTSEPEHDDRKQLLIKVIGILGFLTVISYYIKRHKWSSLKSRKIVFVPKEK---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAM8-1", "uniprot_id": "Q9VAM8_DROME", "id": "Q9VAM8-1", "name": "Cytochrome c1, heme protein, mitochondrial", "aln": "-MANKFRSLNSKLFQLAMSGIQRTSVR----------------PRISFPGRGSGFTGNRKLLGALGALTGTAGLLIYA---LETSVDASSDCVHPAHQHWNHKGLLSALDKESVRRGYTVYKEVCSSCHSLQYMAYRNLVGVCMTEAEAKAEAEAITVRDGPNEEGEYYERPGKLSDHFPSPYANEEAARSANNGSYPPDLSYIVSARKGGEDYVFSLLTGY-CDPPAGFALRDGLYFNPYFSGGAIAMGKVVDNEVVSFEDPNVPASAAQIAKDVCVFLKWTSEPETDERRLLLIKVTLISTFLIGISYYIKRFKWSTLKSRKIFFIPELEAQAKREAEEAAKAARKAKEQECNKCENQNEKKD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07143-1", "uniprot_id": "CY1_YEAST", "id": "P07143-1", "name": "Cytochrome c1, heme protein, mitochondrial", "aln": "----MFSNLSKRWAQRTLSKSFYSTAT-------------------GAASKSGKLT-QKLVTAGVAAAGITASTLLYADSLTAEAMTAAEHGLHAPAYAWSHNGPFETFDHASIRRGYQVYREVCAACHSLDRVAWRTLVGVSHTNEEVRNMAEEFEYDDEPDEQGNPKKRPGKLSDYIPGPYPNEQAARAANQGALPPDLSLIVKARHGGCDYIFSLLTGYPDEPPAGVALPPGSNYNPYFPGGSIAMARVLFDDMVEYEDG-TPATTSQMAKDVTTFLNWCAEPEHDERKRLGLKTVIILSSLYLLSIWVKKFKWAGIKTRKFVFNPPKPRK-------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. .. .: : ..:. . * * :: *: :*.. *.*.* :.::*: *:***: **::**::***:: :*:* **** *: *.: * . * *:: *: ***** *::* **.* :***:**:*: ***** ** **:** **:******* :.*:*. * * :****.* :*.*. : :::.::* .*.: :*:**** .**.* :*** *.*: : :* : * : :*:.**: :*:**: : * ", "identical_positions": 102, "similar_positions": 90, "identity": "27.95%" }, { "cls_id": "homologset.agr.SGD:S000005593", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PT91-1", "uniprot_id": "E9PT91_RAT", "id": "E9PT91-1", "name": "Alpha-1,3-glucosyltransferase", "aln": "MNGWRAPQELAQAQISPLCLGDYGDRARGLNAGALSSQRPSSWRMRTAHGHRLYSPYPHAQRPGSDGTPGMAAFGLAAGSG-HWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHNLPISQWYYEATSEWTLDYPPFFAWFEYALSHIA--KYFDQEMLDIHNLNYYSSRTLLFQRFSVILTDALFVYAVHECCKCIDGKRTGKDLTEKPKFVLSVLLLWNFGLLIVDHIHFQYNGFLSGLLLLSIARLFQKRHIEGAFLFAVLLHFKHIYLYVAPAYGIYLLRSYCFTASKPDGSVRWDSFSIVRVT-ALALIVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYSALDKALCVTGL--------------------ELKLLDPSQIPRASMTSGLVQQSQHTVLPSVSPSATLICTLIAILPSVFCLW--FKPQGPRGFLRCLVLCALSSFMFGWHVHEKAILLAILPMSLLAVEKAGDATIFLILTTTGHYSLFPLLFTAPELPIKILLMSLFTVYSISSLRT------LFRKEKPLFNWMETLYLLGLGPLEVCCEFLFPFTS---WKLKYPFIPLLLTSVYCAVGITYAWIRL---YASVL------------TGCLVSKTKKH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P8H8-1", "uniprot_id": "ALG8_MOUSE", "id": "Q6P8H8-1", "name": "Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "----------------------------------------------------------------------MAASGSATAGG-HWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEATSEWTLDYPPFFAWFEYALSHIA--KYFDQEMLNIHNLNYYSSRTLLFQRFSVILTDALFVYAVHECCKCIDGKRTGKDLTEKPKFILSVLLLWNFGLLIVDHIHFQYNGFLSGLLLLSIARLFQKRHIEGALLFAVLLHLKHIYLYVAPAYGVYLLRSYCFTASKPDGSVRWSSFSVVRVT-SLGLIVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIGL--------------------KLKLLDPSQIPRASMTSGLVQQFQHTVLPSVSPLATLICTLIAILPSVFCLW--FKPQGPRGFLRCLVLCALSSFMFGWHVHEKAILLAILPMSLLSVEKAGDATVFLILATTGHYSLFPLLFTAPELPIKILLMLLFTVYSISSLKT------LFRKEKPLFNWMETVYLLGLGPLEVCCEFLLPFTS---WKLKYPFIPLLLTSVYCAVGITYAWTRL---YASVL------------TGSLVSKTKKH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BVK2-1", "uniprot_id": "ALG8_HUMAN", "id": "Q9BVK2-1", "name": "Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "----------------------------------------------------------------------MAALTIATGTG-NWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEATSEWTLDYPPFFAWFEYILSHVA--KYFDQEMLNVHNLNYSSSRTLLFQRFSVIFMDVLFVYAVRECCKCIDGKKVGKELTEKPKFILSVLLLWNFGLLIVDHIHFQYNGFLFGLMLLSIARLFQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKPDGSIRWKSFSFVRVI-SLGLVVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIGL--------------------KLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICTLIAILPSIFCLW--FKPQGPRGFLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPLLFTAPELPIKILLMLLFTIYSISSLKT------LFRKEKPLFNWMETFYLLGLGPLEVCCEFVFPFTS---WKVKYPFIPLLLTSVYCAVGITYAWFKL---YVSVL------------IDSAIGKTKKQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3V8-1", "uniprot_id": "ALG8_DROME", "id": "Q9W3V8-1", "name": "Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "-------------------------------------------------------------------------------MK-DLFWHLVGIATGLKILLIPAYHSTDFEVHRNWLAITHSLPLNQWYVDATSEWTLDYPPFFAYFEWLLSQVA--KYVDPRMLVVDNLNYESKATVYFQRLSVIVTDLVYVLGVRSCLGSLG---LGRDTQQ--FFAASMLLLLNVGLIFVDHIHFQYNGLLFGILLLSIGSLIRQRFLWSAFAFAVLLNFKHIFLYMAPAFGVYLLRFYCLEQASVVSAVG----AVVKLL-VVGLTPFAVS---FGPFW--QQLPQVLSRLFPFKRGLTHAYWAPNFWALYNAADKLAAGV-----------------------LKVQDGG----ASTTSGLVQEVRHSVLPAITPPVTFALTALFMLPILVKLFRSAKKQSPLVFLRAVVLCGCSSFVFGWHVHEKAILMVLLPLCLLTLVNREDARYAYVLGIAGYFSLFPLLFDADLYIPRYSLYMSYVAMMYGQLYR------IFPGFR-GFHTLEWLYMLGFMAIPLYEHLLSFLLH---LDQRLPFLPLLLTSVYSALGVLYFFGAY---YLYALGISWGKVPIASSTSAAAVKRKRKTK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40351-1", "uniprot_id": "ALG8_YEAST", "id": "P40351-1", "name": "Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "-----------------------------------------MKGDRSRQNMAVTKKAKLKKNDEPKKVLKTAATEKGEGSKRYSLWNFWISTLFLKLLLIPDYFSTDFDVHRNWLAITNKLPISEWYYEHTSQWTLDYPPFFAYFEWFLSQFVPKSVRDDGCLDIVEIGKFGLPTIVFQRLTVIFSEILLFVILQIYINTTK---LSERSQS---FVVASSIVLSPGFLIIDHIHFQYNGFLFAILIGSIVAAKNKRYILCAVLYTTAICFKHIFLYLAPCYFVFLLRAYVLNVNNFKFKSYKDFLFLIRWANLLKLATVVVGIFTICFLPFAHQMPQVLSRLFPFSRGLTHAYWAPNFWALYSFMDKILTTVMLKLPYVHTFATKFIKPPLIPQNIKEINERLAANNNGSKGLVQDVFFVILPQIPPKLTFILTIFYQVLAVLPLL--FDPSFKR-FVGSLTLCGLASFLFGWHVHEKAIMLVIIPFTFLVGFDRRLLVPFMLVASAGYVSLYPLLYKGQDFFIKTLYTYVWCIIYFAAFRKTTKISSSVERRIFFLDRLALTYIFSLLPIVTVLQILDEVKWRYSFLQKFEFLGLMIYSVYCSLGIISSWFALSWLYN---------------FDELLWQ------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . ** **** *.****:*********:.**:.:** : **:**********:**: **:.. . * * : ::. . *: ***::**. : : . :: .. . * : :: . *::::*********:* .::: ** .:*.: *. ::. : :***:**:**.: ::*** * : . .:: : * . *. : : :*:***:******.*** ************. ** :* : . :.****: . :** :.* *: * : : :. * . . *: .:.**. :**:**********::.::*: :* . :: :*: **:***: . : : . : . :. : *::.: .: .:: . : *: *:: ***.::*: : * . : ", "identical_positions": 146, "similar_positions": 147, "identity": "22.53%" }, { "cls_id": "homologset.agr.SGD:S000005595", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CWK8-1", "uniprot_id": "SNX2_MOUSE", "id": "Q9CWK8-1", "name": "Sorting nexin-2", "aln": "--------------------------------------------------------------------------------------------------------------------------MAAEREPPPL-----------GDVKPTDFEELEDGEDLFTSTVSTLESSPSSPE-PASLPAEDISANSNGSKPVEVVLDDDREDLFAEATEEVSLDSPERELILSSEPSPAVTPVTPTTLIAPRIESKSISAPVIFDRSRDEIEE-------EANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSS-----STEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESS-ELPRAVNTQALSGAGILRMVNKAADAVN---------------------------------KMTIKMNESDAWFEEKQQQFENLDQQLRKLHASVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQITLLKKRETEAKMMVANKPDKIQQAKNEIR----EWEAKVQQGERDFEQISKTIRKEVGRFEKERVKDFKAVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7ENB2-1", "uniprot_id": "F7ENB2_RAT", "id": "F7ENB2-1", "name": "Sorting nexin-2", "aln": "--------------------------------------------------------------------------------------------------------------------------MAAEREPPPL-----------GDVKPTDFEELEDGEDLFTSTVSTLESSPSSPE-PASLPAEDISANSNGSRPVEVTLDDDREDLFAEATEEVSLDSPEREPIMSSEPSPAVTPITPTTLIAPRIESKSISAPVIFDRSREEIEE-------EANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSS-----STEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESS-ELPRAVNTQALSGAGILRMVNKAADAVN---------------------------------KMTIKMNESDAWFEEKQQQFENLDQQLRKLHASVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQITLLKKRETEAKMMVANKPDKIQQAKNEIREEIEEWEAKVQQGERDFEQISKTIRKEVGRFEKERVKDFKAVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60749-1", "uniprot_id": "SNX2_HUMAN", "id": "O60749-1", "name": "Sorting nexin-2", "aln": "--------------------------------------------------------------------------------------------------------------------------MAAEREPPPL-----------GDGKPTDFEDLEDGEDLFTSTVSTLESSPSSPE-PASLPAEDISANSNGPKPTEVVLDDDREDLFAEATEEVSLDSPEREPILSSEPSPAVTPVTPTTLIAPRIESKSMSAPVIFDRSREEIEE-------EANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSS-----STEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESS-ELPRAVNTQALSGAGILRMVNKAADAVN---------------------------------KMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIR----EWEAKVQQGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WV80-1", "uniprot_id": "SNX1_MOUSE", "id": "Q9WV80-1", "name": "Sorting nexin-1", "aln": "------------------------------------------------------------------------------------------------------------------MASGGGGCSASERLPPPFPGMDPESEGAAGASEPEAGDSDTEGEDIFTG--AAAATKPQSPKKTTSLFPIKNGSKENG---IHEDQDQEPQDLFADATVELSLDSTQN----NQKTMPGKTLTS-----HSPQEATNSPKP---QPSYEELEE-------EEQEDQFDLTVGITDPEKIGDGMNAYVAYKVTTQTSLPMFRSRQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSS-----SAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKE-ELPRAVGTQALSGAGLLKMFNKATDAVS---------------------------------KMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTALFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDSFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKKRESEARLLWANKPDKLQQAKDEIT----EWESRVTQYERDFERISTVVRKEVTRFEKEKSKDFKNHVMKYLETLLHSQQQLAKYWEAFLPEAKAIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99N27-1", "uniprot_id": "SNX1_RAT", "id": "Q99N27-1", "name": "Sorting nexin-1", "aln": "------------------------------------------------------------------------------------------------------------------MASGGGGCSASERLPPPFPGMDPESEGAAGGSEPEAGDSDTEGEDIFTG--AAAASKPQSPKKTTSLFPIKNGSKENG---IHEEQDQEPQDLFADATVELSLDSTQN----NQKTMPGKTLIP-----HPTQEATNSPKP---QPSYEELEE-------EEQEDQFDLTVGITDPEKIGDGMNAYVAYKVTTQTSLPMFRSRQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSS-----SAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKE-ELPRAVGTQALSGAGLLKMFNKATDAVS---------------------------------KMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTALFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKKRESEARLLWANKPDKLQQAKDEIT----EWESRVTQYERDFERISTVVRKEVTRFEKEKSKDFKNHVIKYLETLLHSQQQLAKYWEAFLPEARAIS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13596-1", "uniprot_id": "SNX1_HUMAN", "id": "Q13596-1", "name": "Sorting nexin-1", "aln": "------------------------------------------------------------------------------------------------------------------MASGGGGCSASERLPPPFPGLEPESEGAAGGSEPEAGDSDTEGEDIFTG--AAVVSKHQSPKITTSLLPINNGSKENG---IHEEQDQEPQDLFADATVELSLDSTQN----NQKKVLAKTLIS-----LPPQEATNSSKP---QPTYEELEE-------EEQEDQFDLTVGITDPEKIGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSS-----SAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKE-ELPRAVGTQTLSGAGLLKMFNKATDAVS---------------------------------KMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKKREAEARLLWANKPDKLQQAKDEIL----EWESRVTQYERDFERISTVVRKEVIRFEKEKSKDFKNHVIKYLETLLYSQQQLAKYWEAFLPEAKAIS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQQ6-1", "uniprot_id": "Q9VQQ6_DROME", "id": "Q9VQQ6-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MEVESPEHTRDFAEVDINNG--AATGSEDEEEEVPAPG---------------SVTLDRNESDLFVSALSPSSIGDIHP--------------------------------------LQEVLTD-------DGD---YFISIVVSDPQKIGDGMGSYLAYKVTTKTNIPKFKRSEFSTLRRFSDFLGIHDLLVGKYMRLGRIIPPAPSKNIIGSTKVKISPQQSEPGTPMTQEWVEIRRAALERFVHRTAQHPVLRVDLDFMNFLESDQELPRSVNTSALSGAGVIRLFNKVGETVN---------------------------------KITYKMDENDPWFDDKITEVESLDANLQKLHNAMKSLVTSRRELSLLTGLVAKSAAMLSTCEEHTGLSRALSNLADVEEKIELLRSEQANSDFFILAEFIKDYLGLFGAIKCIFHERVKAFQNWQYAQMQLSKRRENRGRFELANRADKLDQAQQEVD----EWQGKVQRCQQQFDDISAEIKREMERFELTRVKDFKVNIIKYIEDQMAHQQQIVSYWEAFAPFAREIV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q92331-1", "uniprot_id": "VPS5_YEAST", "id": "Q92331-1", "name": "Vacuolar protein sorting-associated protein 5", "aln": "MDYEDNLEAPVWDELNHEGDKTQSLVSNSIESIGQISTNEERKDNELLETTASFADKIDLDSAPEWKDPGLSVAGNPQLEEHDNSKADDLINSLAPEQDPIADLKNSTTQFIATRESGGALFTGNANSPLVFDDTIYDANTSPNTSKSISGRRSGKPRILFDSARAQRNSKRNHSLKAKRTTASDDTIKTPFT--DPLKKAEKENEFVEEPLDDRNERRENNEGKFTASVEKNILEQVDRPLYNLPQTGANISSPAEVEENSEKFGKTKIGSKVPPTEKAVAFKVEVKDPVKVGELTSIHVEYTVISESSLLELKYAQVS--RRYRDFRWLYRQLQNNH--WGKVIPPPPEKQSVGSFKEN---------------FIENRRFQMESMLKKICQDPVLQKDKDFLLFLTSDDFSSESKKRAFLTGSGAINDSNDLSEVRISEIQLLGAEDAAEVLKNGGIDAESHKGFMSISFSSLPKYNEADEFFIEKKQKIDELEDNLKKLSKSLEMVDTSRNTLAASTEEFSSMVETLASLNVSEPNSELLNNFADVHKSIKSSLERSSLQETLTMGVMLDDYIRSLASVKAIFNQRSKLGYFLVVIENDMNKKHSQLGKLGQNIHSEKFREMRKEFQ----TLERRYNLTKKQWQAVGDKIKDEFQGFSTDKIREFRNGMEISLEAAIESQKECIELWETFYQTNL---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : . : :. . . . .::. .. . . : : . : : :.** *:*: . :: * * :::.: : :.: **: ** :: * :: * ::**.*.*. :* * : ::* ** :* ::: :.*.: * *. ** .. ..: *:*:* :. *. :. . * :* * :* :* :.: : .*:** :: : *. *: * .:. *.. : *. *.::*:*.:.*. ...: : :. ::.**: :. :: *..* * : : *::. .:: :.:*: : :.*. : : ::::: :. :: *. *. : ::*: : :* : *:: . **:* ", "identical_positions": 64, "similar_positions": 161, "identity": "9.1%" }, { "cls_id": "homologset.agr.SGD:S000005596", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R5A6-1", "uniprot_id": "TB22A_MOUSE", "id": "Q8R5A6-1", "name": "TBC1 domain family member 22A", "aln": "MASDGARKQFWKRSNSKVPG----------SIQHVYGAQHPPFDPLLHGTLLKSTPKVPTTPVKAKRVS--TFQEFESNTSDAWDAGEDDDE-------LLAMATESLNSEVVMETAHRVLRN--HSQRQSQPSQKT-TEPEPEPQPIAE-----------------------------PPVPPSGDLRLVKSVSESHTPCPSESTGDTVPLQRSQSLPHSATVTLSG-TSDPHALADSALSKRETSRLDKFKQLLAGPN--------TDLEELRKLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYSSRNDEVHQDTYRQIHIDIPRMSP-EALILQPKVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYTDREDVDKVDVSS----VPAEVLRNIEADTYWCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDERVHRHLDGHEVRYLQFAFRWMNNLLMRELPLRCTIRLWDTYQSEP------------------------------------------------------------EGFSHFHLYVCAAFLVRWRREILEERDFQELLLFLQNLPTARWDDQDVSLLLAEAYRLKFAFADAPNHYKK--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZPV1-1", "uniprot_id": "A0A8I5ZPV1_RAT", "id": "A0A8I5ZPV1-1", "name": "", "aln": "MASDGARKQFWKRSNSKVPG----------SIQHVYGAQHPPFDPLLHGTLLKSTPKVPTTPVKAKRVS--TFQEFESNTSDAWDAGEDDDE-------LLAMATESLNSEVVMETAHRVLRN--HSQRQNQPSQK---KPEPEPQPIAE-----------------------------PPVAPSGDLRLVKSVSESHTPCPSESTSDTVPLQRSQSLPHSATVTLSG-TSDTHALGGSALSKRETSRLDKFKQLLAGPN--------TDLEELRKLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYNSRNDEVHQDTYRQIHIDIPRMSP-EALILQPKVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYTDQEDVDKVDVSS----VPAEVLRNIEADTYWCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDERVHRHLDGHEVRYLQFAFRWMNNLLMRELPLRCTIRLWDTYQSEP------------------------------------------------------------EGFSHFHLYVCAAFLVRWRREILEERDFQELLLFLQNLPTARWDDQDVSLLLAEAYRLKFAFADAPNHYKKSSTPLPRH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WUA7-1", "uniprot_id": "TB22A_HUMAN", "id": "Q8WUA7-1", "name": "TBC1 domain family member 22A", "aln": "MASDGARKQFWKRSNSKLPG----------SIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVS--TFQEFESNTSDAWDAGEDDDE-------LLAMAAESLNSEVVMETANRVLRN--HSQRQGRPTLQEGPGLQQKPRPEAE-----------------------------PPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGG-TSDPSTLSSSALSEREASRLDKFKQLLAGPN--------TDLEELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSP-EALILQPKVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSG----VPAEVLCNIEADTYWCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIRLWDTYQSEP------------------------------------------------------------DGFSHFHLYVCAAFLVRWRKEILEEKDFQELLLFLQNLPTAHWDDEDISLLLAEAYRLKFAFADAPNHYKK--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NU19-1", "uniprot_id": "TB22B_HUMAN", "id": "Q9NU19-1", "name": "TBC1 domain family member 22B", "aln": "MAAE-NSKQFWKR-SAKLPG----------SIQPVYGAQHPPLDPRLTKNFIKERSKVNTVPLKNKKAS--SFHEFARNTSDAWDIGDDEEE------DFSSPSFQTLNSKVALAT--------------AAQVLENHSKLRVKPERSQS-----------------------------TTSDVPANYKVIKSSSDAQLSRNSSDTCLRNPLHKQQSLPLRPIIPLVARISDQNASGAPPMTVREKTRLEKFRQLLSSQN--------TDLDELRKCSWPGVPREVRPITWRLLSGYLPANTERRKLTLQRKREEYFGFIEQYYDSRNEEHHQDTYRQIHIDIPRTNPLIPLFQQPLVQEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFLSEYVE-EDVENFDVTN----LSQDMLRSIEADSFWCMSKLLDGIQDNYTFAQPGIQKKVKALEELVSRIDEQVHNHFRRYEVEYLQFAFRWMNNLLMRELPLRCTIRLWDTYQSEP------------------------------------------------------------EGFSHFHLYVCAAFLIKWRKEILDEEDFQGLLMLLQNLPTIHWGNEEIGLLLAEAYRLKYMFADAPNHYRR--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B1S8-1", "uniprot_id": "A0A8M3B1S8_DANRE", "id": "A0A8M3B1S8-1", "name": "", "aln": "MATD-NRIHFWRK-NPKVPG----------SLQPVYGAQHPPLDPRRHR-PLKDTPKASSV-VKSKKPS--TFHEFARSTNDAWDIDDEEDDG---IFSLKQSSSSPVQSRSTPQTPCLKLFKVPDDTELGTRSLDRQEPISTNPDQERL-----------------------------DVESGPANGRVVKSCSDAQLNVNTA----RNPLQKQQSLPVRPVIPLVARISDQNASGAPPMTVREKTRLDKFKQLLSSSN--------TDLEELRKHSWSGIPREVRPVTWRLLSGYLPANRERRDLVLQRKREEYFGFIEQYYHSRTDENHRDTYRQIHIDIPRTNPLIPLFQQPLVQEVFERILFIWAIRHPASGYVQGINDLVTPFFVVFLSEFVE-EDVENFEMAS----LPLDTQRNIEADSFWCMSKLLDGIQDNYTFAQPGIQIKVKALEELVSRIDEDVHVHFQKCEVEYLQFAFRWMNNLLMRELPLRCTIRLWDTYQAES------------------------------------------------------------EGFSHFHLYVCAAFLIKWRKEILSMLDFQNLLMLLQNLPTIHWGNEEVGLLLAEAYRLKYMFADAPSHYKR--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08484-1", "uniprot_id": "GYP1_YEAST", "id": "Q08484-1", "name": "GTPase-activating protein GYP1", "aln": "MGVRSAAKEMHERDHNSDSSSLVTSLMKSWRISSASSSKKPSLYKMNTTESTSLPSGYASSADRDRRTSDGNFEAMAKQQASTRRTSNSYSPLRYVNPTLSTASNESPRPALLLRQHHQRHHHHQQPRHSSSGSVGNNCSNSTEPNKKGDRYFKDLDEDWSAVIDDYNMPIPILTNGGFGTPVAPTRTLSRKSTSSSINSISNMGTSAVRNSSSSFTYPQLPQLQKEK-TNDSKKTQLEIENERDVQELNSIIQRISKFDNILKDKTIINQQDLRQISWNGIPKIHRPVVWKLLIGYLPVNTKRQEGFLQRKRKEYRDSLKHTFSDQHS-RDIPTWHQIEIDIPRTNPHIPLYQFKSVQNSLQRILYLWAIRHPASGYVQGINDLVTPFFETFLTEYLPPSQIDDVEIKDPSTYMVDEQITDLEADTFWCLTKLLEQITDNYIHGQPGILRQVKNLSQLVKRIDADLYNHFQNEHVEFIQFAFRWMNCLLMREFQMGTVIRMWDTYLSETSQEVTSSYSMSSNDIKPPVTPTEPRVASFVTPTKDFQSPTTALSNMTPNNAVEDSGKMRQSSLNEFHVFVCAAFLIKWS-DQLMEMDFQETITFLQNPPTKDWTETDIEMLLSEAFIWQSLYKDATSHWL---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. .: .: . .. :. . .:::*.: . : : :: * .*. : . .: .:. . : : .. .. :* . ** *.: . : * . : .* . *: .*:.: * :: : : ::**: ** *:*: **:.*:** ****.* .*: ****::** ::: : .: . . *::**.***** .* .* * : ::***::********************** .*: *: .::: .:: . : : .:***::**::***: * *** ..**** :** *.:**.*** :: *: .*.::******** *****. : .**:**** :*. ..:..**::******::* : * *** : :*** ** * : :: :**:**: : : **..*: ", "identical_positions": 146, "similar_positions": 150, "identity": "22.5%" }, { "cls_id": "homologset.agr.SGD:S000005600", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P45352-1", "uniprot_id": "TYSY_RAT", "id": "P45352-1", "name": "Thymidylate synthase", "aln": "MLVE----GSELQS-----GAQQP--RTEA-PQHGELQYLRQVEHIMRCGFKKEDRTGTGTLSVFG-MQARYSLR-DEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVRIWDANGSRDFLDSLGFSARQEGDLGPVYGFQWRHFGADYKDMDSDYSGQGVDQLQKVIDTIKTNPDDRRIIMCAWNPKDLPLMALPPCHALCQFYVVN---------GELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLQPGDFVHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVETIDDFKVEDFQIEGYNPHPTIKMEMAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07607-1", "uniprot_id": "TYSY_MOUSE", "id": "P07607-1", "name": "Thymidylate synthase", "aln": "MLVV----GSELQS-----DAQQL--SAEA-PRHGELQYLRQVEHILRCGFKKEDRTGTGTLSVFG-MQARYSLR-DEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVRIWDANGSRDFLDSLGFSARQEGDLGPVYGFQWRHFGAEYKDMDSDYSGQGVDQLQKVIDTIKTNPDDRRIIMCAWNPKDLPLMALPPCHALCQFYVVN---------GELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLQPGDFVHTLGDAHIYLNHIEPLKIQLQREPRPFPKLKILRKVETIDDFKVEDFQIEGYNPHPTIKMEMAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04818-1", "uniprot_id": "TYSY_HUMAN", "id": "P04818-1", "name": "Thymidylate synthase", "aln": "MPVA----GSELPRRPLPPAAQER--DAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFG-MQARYSLR-DEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVN---------SELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O76511-1", "uniprot_id": "TYSY_DROME", "id": "O76511-1", "name": "Thymidylate synthase", "aln": "MVLTPTKDGPDQESMPLPADNGESPSKQQAPVNRDEMHYLDLLRHIIANGEQRMDRTEVGTLSVFG-SQMRFDMR-NSFPLLTTKRVFFRAVAEELLWFVAGKTDAKLLQAKNVHIWDGNSSREFLDKMGFTGRAVGDLGPVYGFQWRHFGAQYGTCDDDYSGKGIDQLRQVIDTIRNNPSDRRIIMSAWNPLDIPKMALPPCHCLAQFYVSEKR-------GELSCQLYQRSADMGLGVPFNIASYALLTHMIAHVTGLKPGDFVHTMGDTHVYLNHVEPLKEQLERTPRPFPKLIIKRQVQDIEDFRFEDFQIVDYNPHPKIQMDMAV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06785-1", "uniprot_id": "TYSY_YEAST", "id": "P06785-1", "name": "Thymidylate synthase", "aln": "MTMD--------------------------GKNKEEEQYLDLCKRIIDEGEFRPDRTGTGTLSLFAPPQLRFSLRDDTFPLLTTKKVFTRGIILELLWFLAGDTDANLLSEQGVKIWDGNGSREYLDKMGFKDRKVGDLGPVYGFQWRHFGAKYKTCDDDYTGQGIDQLKQVIHKLKTNPYDRRIIMSAWNPADFDKMALPPCHIFSQFYVSFPKEGEGSGKPRLSCLLYQRSCDMGLGVPFNIASYALLTRMIAKVVDMEPGEFIHTLGDAHVYKDHIDALKEQITRNPRPFPKLKIKRDVKDIDDFKLTDFEIEDYNPHPRIQMKMSV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : * :** .:*: * : *** .****:*. * *:.:* : *******:** :.: *****: *.*:*: *. :.*:***.*.**::**.:**. * ****************.* :.**:*:*:***::**..::.** ******.**** *: ******* :.**** .*** ***** ***************** ***::..::**:*:**:**:*:* :*::.** *: * ******* * *.*: *:**: **:* .***** *:*.*:*", "identical_positions": 164, "similar_positions": 76, "identity": "49.7%" }, { "cls_id": "homologset.agr.SGD:S000005601", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VDS8-1", "uniprot_id": "STX18_MOUSE", "id": "Q8VDS8-1", "name": "Syntaxin-18", "aln": "MAVDITLLFRASVKTVK-TRNKALGVAVGGGADGSRDELFRRSPR-PKGDFSSRAREVISHIGKLRDFLLEHRKEYINAYSHTMSDYGRMTDTERDQIDQDAQIF-------IRTCSEAIHQLRTEAHKEIHSQQVKEHRTAVLDFVDDYLKRVCKLYS-EQRAIRVKRVVDKKRLSKLEPEP-----------------------HTKRKDSTS-EKAPQNASQD-------------------------SEGKPAAEELPEKPLAES------------------QPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEVRQIEGKVVEISRLQEIFTEKVLQQETEIDSIHQLVVGATENIKEGNEDIREAIKNNAGFRVWILFFLVMCSFSLLFLDWYDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68FW4-1", "uniprot_id": "STX18_RAT", "id": "Q68FW4-1", "name": "Syntaxin-18", "aln": "MAVDITLLFRASVKTVK-TRNKALGVAVGGGADGSRDELFRRSPR-PKGDFSSRAREVISHIGKLRDFLLEHRKEYINAYSHTMSEYGRMTDTERDQIDQDAQIF-------MRTCKDAIQQLRTEAHKEIHSQQVKEHRTAVLDFVEDYLKRVCKLYS-EQRAIRVKRVVDKKRLSKLEPEP-----------------------HTKRKEPAS-EKSSHNASQD-------------------------SEEKPAAEDLPEKPLAES------------------QPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEVRQIEGKVVEISRLQEIFTEKVLQQETEIDSIHQLVVGATENIKEGNEDIREAIKNNAGFRVWILFFLVMCSFSLLFLDWYDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P2W9-1", "uniprot_id": "STX18_HUMAN", "id": "Q9P2W9-1", "name": "Syntaxin-18", "aln": "MAVDITLLFRASVKTVK-TRNKALGVAVGGGVDGSRDELFRRSPR-PKGDFSSRAREVISHIGKLRDFLLEHRKDYINAYSHTMSEYGRMTDTERDQIDQDAQIF-------MRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYS-EQRAIRVKRVVDKKRLSKLEPEP-----------------------NTKTRESTSSEKVSQSPSKD-------------------------SEENPATEERPEKILAET------------------QPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEVRQIEGRVVEISRLQEIFTEKVLQQEAEIDSIHQLVVGATENIKEGNEDIREAIKNNAGFRVWILFFLVMCSFSLLFLDWYDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4VBI7-1", "uniprot_id": "STX18_DANRE", "id": "Q4VBI7-1", "name": "Syntaxin-18", "aln": "MAADITLLFKASVKTVK-TRNKALGLMETTGREEP-GAQKRPRPR-QRDSFSCKAREVISNISKLKDFLLQHRKDYVNAGSVMSSEVSRMTDSERDQIDQDAQIF-------MRTCAEAISQLRSEMDKKQVSMQVKDHRAAVLDLIDSYLKGVCKLYS-EQRAVRVKRVVDKKRLSRLEPE----------------------------------QINTEKRQSD-------------------------GEEN-------DKPVSDG------------------NVDL--WEENRVEDDLSPEEIQMFEQENQRLVGEMNSLLDEVRQIEGKVVEISRLQEIFSEKVLQQETEIDSIHQLVVGATENVKEGNEDIREAIKNNAGFRVWILFFLVMCSFSLLFLDWYDS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC58-1", "uniprot_id": "Q9VC58_DROME", "id": "Q9VC58-1", "name": "Syntaxin-18", "aln": "--MDITQSFKASVMTVR-LQRK----AELAGKAKPATVPTKTGPIGPKDDFAKQAKEVCNKITSLRNVLIENRTAYMRIGQHLKSAA-HMTDAQRDLIDRESEKF-------VTFYTQHLAKMRSDWKSAKRKPQERQHIDAVLDLLVSYLHSVEQIYL-DQKKYRVQHELETYRLLKLAADKKKIPVRPAGSNSGKLGRRQVSNDDSEATKSSSQANGNHDESADNDWNNDAWGDWDEDEEGDEVDDHDGEKGKEANQANQHKPRTRKRSKANRSDLNNSSSKMALDEELQQQQEADDDDPLSAEDVQLFEAENVHIYNFLQGVSEEVEQIEKNVVDIAQLQDIFTEKVAMQQHNIDRIVSAVVGTTENVKDANEQIRQATQRNAGLRVWSLFFLLVMSFSLLFLDWYYD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41834-1", "uniprot_id": "UFE1_YEAST", "id": "P41834-1", "name": "Syntaxin UFE1", "aln": "MMSDLTPIFRKYVAVIDDARNEQNGIDDHVERKQEDFGNSNETCEMFRDSFIKECARLLKFLVELNKVIKQIEKNYLDDFNMSDAEKDEFDMECRLQIQQYFKKFEFLENYEMERHNLSLKRFQSKSHRWSKILSNKNDNTKHVIHPQDIENGVYEFRLGVLRCLNLWIKYVSSKFTTIQQER--------------------LILENKMNFNSTPMPTLSNNADD-------------------------FSADAIDISVSQSAPVET-----------------VQDEVKHYEETIS--KLTQEQLQVLETEHSELLNQKNEQLKKVETINKTILDIVNIQNELSNHLTVQSQNINLMLNNQDDIELNIKKGNKELRKAKRAAGRTAKMTTYGAIIMGVFILFLDYVG-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:* *: * .: :.: . :..* .. .: . : .*...: : .. *: . : .: * *:: : * : : ::::. . . ::. : . : * :: : .: . :: : : . * . . .. : :: : *: *::*::* *: .: . : .:*. *: :::* .:*: ::::: *. :*: : . . *:*..*:::*:* : . : :: .. :****: ", "identical_positions": 32, "similar_positions": 114, "identity": "7.79%" }, { "cls_id": "homologset.agr.SGD:S000005603", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L225-1", "uniprot_id": "A0ABK0L225_RAT", "id": "A0ABK0L225-1", "name": "DNA/RNA-binding protein KIN17", "aln": "MGKSDFLSPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIEEQVR--RGLEGKE-QETPVFTELSRE-NDEEKVTFNLNKGAGSSAGATTSKSSSLGPSALKMLGSTASVRRKESSQSSAQP-AKKKKKSALDEIMEIEEEKK-RTARTDSWLQPGIIVKIITKKLGEKYHKKKGVVKEVIDRYTAVVKMTDSGDRLKLDQTHLETVIPAPGKRVLVLNGGYRGNEGTLESINEKTFSATIVIETGPLKGRRLEEPRTEPRTLHLLGKRTTAELNPQPKTSIF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K339-1", "uniprot_id": "KIN17_MOUSE", "id": "Q8K339-1", "name": "DNA/RNA-binding protein KIN17", "aln": "MGKSDFLSPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIEEQVR--RGLEGKE-QETPVFTELSRE-NEEEKVTFNLNKGAGGSAGATTSKSSSLGPSALKLLGSAASGKRKESSQSSAQP-AKKKK-SALDEIMELEEEKK-RTARTDAWLQPGIVVKIITKKLGEKYHKKKGVVKEVIDRYTAVVKMTDSGDRLKLDQTHLETVIPAPGKRVLVLNGGYRGNEGTLESINEKAFSATIVIETGPLKGRRVEG----------IQYEDISKLA--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60870-1", "uniprot_id": "KIN17_HUMAN", "id": "O60870-1", "name": "DNA/RNA-binding protein KIN17", "aln": "MGKSDFLTPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIEEQVR--RGLEGKE-QEVPTFTELSRE-NDEEKVTFNLSKGACSSSGATSSKSSTLGPSALKTIGSSASVKRKESSQSSTQSKEKKKKKSALDEIMEIEEEKK-RTARTDYWLQPEIIVKIITKKLGEKYHKKKAIVKEVIDKYTAVVKMIDSGDKLKLDQTHLETVIPAPGKRILVLNGGYRGNEGTLESINEKTFSATIVIETGPLKGRRVEG----------IQYEDISKLA--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N732-1", "uniprot_id": "A0A8M1N732_DANRE", "id": "A0A8M1N732-1", "name": "DNA/RNA-binding protein KIN17", "aln": "MGKADFLTPKAIANRIKAKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPNQFLSYFSDEFKTDFLELLRRRFGTKRVHNNIVYNEYISHREHVHMNATQWETLTDFTKWLGREGFCKVDETPKGWYVQYIDRDPETIRRQEELERKKKQDLDDEERSAKFIEEQVR--RGREGREPTEEPVFTELQRK-SEDEKVAFNLEIAAAGP----SKPSTTLGPSALK---TTASVKRKESSLSGEFK--DKKKKSALDEIIEMEEQKK-KSVRSDNWIQENIVVKVVTKKLGEKYYKKKAIIRELQGKYTAVVKMVDSGDKLKLDQSHVETVIPAPGKRVLILNGQYRGTEAILEGINEHKFSATLTLDSGRMKGKTVEG----------IAYEDFSKLA--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPH4-1", "uniprot_id": "Q9VPH4_DROME", "id": "Q9VPH4-1", "name": "", "aln": "MGRAEVGTPKYLANKMKSKGLQKLRWYCQMCEKQCRDENGFKCHTMSESHQRQLLLFADNPGKFLHSFSKEFSDGYMELLRRRFGTKRTSANKIYQEYIAHKEHIHMNATRWLTLSDYVKWLGRTGQVIADETEKGWFVTYIDRSPEAMERQAKADRKEKMEKDDEERMADFIEQQIKNAKAKDGEEDEGQEKFTELKREENEPLKLDIRLEK--------KFQPDTVLGKSALAKRPAPEAEEKVFKKPKSVAG--DSQTRSVLDEIIKQEESKKERANRKDYWLHKGIVVKFISKSMGEKFFKQKAVVLDVIDRYQGKIKFLETGEKLKVDQAHLETVIPALDKPVMVVNGAYRGSEALLRKLDERRYSVSVEILHGPLKGRIVDN----------VQYEDISKLHGA------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40962-1", "uniprot_id": "RTS2_YEAST", "id": "P40962-1", "name": "Zinc finger protein RTS2", "aln": "--MADYDSAKYWSKQGARRGLQKTRYYCQICQRQCKDANGFQSHNKSPSHLRKISQVTAED---ARRYNIQFEKGFLQLLKQRHGEKWIDANKVYNEYVQDRDHVHMNATMHRSLTQFVRYLGRAGKVDVDMD--------IDDTSENVEG----------------------------------------------------------------------------------------PLLIRIHPSSLSSPSE----------DGMLRSQQEEQ-----------EVIAAELLKRQLNR-------AKRQTEKVYQPEMKSEISGD--------------STLKRVQVTFHGNGRVNKKKKKVPPRKDGIKFR-----------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :.* ::: :**** *:***:*::**:* ***:.* * ** *:: : : :. :* .:::**::*.* * * :*:**: .::*:***** :*:::.::*** * .* ** .* :. . . .. .. * ::. ::.:: * .:.:.:.:.. : * :* :*: : * : : : . : : . .. ", "identical_positions": 52, "similar_positions": 85, "identity": "12.5%" }, { "cls_id": "homologset.agr.SGD:S000005605", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3KR82-1", "uniprot_id": "S39A9_RAT", "id": "Q3KR82-1", "name": "Zinc transporter ZIP9", "aln": "-MDDFLSISLLSLAMLVGCYVAGIIPLAVNFSEERLKLVTVLGAG---LLCGTALAVIVPEGVHALYEEVLEGKHHQASEAKQNVIASDKAAEISVVHEHEHSHDHTQLHAYIGVSLVLGFVFMLLVDQIGSSHVHSTDDPESARPSSS---------KITTTLGLVVHAAADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAG-LERNRIRKHLLVFALAAPAMSMLTYLGLSKSSKEALSEVNATGVAMLFSAGTFLYVATVHVLPED--TST-----------------NQS-------GSSLS-------------PRPLPSGKN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFU1-1", "uniprot_id": "S39A9_MOUSE", "id": "Q8BFU1-1", "name": "Zinc transporter ZIP9", "aln": "-MDDFLSISLLSVAMLVGCYVAGIIPLAVNFSEERLKLVTVLGAG---LLCGTALAVIVPEGVHALYEEVLEGKHHQTSEMKQNGIASDKAAEISSVHEHEHSHDHTQLHAYIGVSLVLGFVFMLLVDQIGSSHVHSSDDPETARPSSS---------KITTTLGLVVHAAADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAG-LERNRIRKHLLVFALAAPAMSMLTYLGLSKSSKEALSEVNATGVAMLFSAGTFLYVATVHVLPEV--GGM-----------------GHSHKPDTTGGRGLSRLEVAALVLGCLIPLILSIGHQH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NUM3-1", "uniprot_id": "S39A9_HUMAN", "id": "Q9NUM3-1", "name": "Zinc transporter ZIP9", "aln": "-MDDFISISLLSLAMLVGCYVAGIIPLAVNFSEERLKLVTVLGAG---LLCGTALAVIVPEGVHALYEDILEGKHHQASET-HNVIASDKAAEKSVVHEHEHSHDHTQLHAYIGVSLVLGFVFMLLVDQIGNSHVHSTDDPEAARSSNS---------KITTTLGLVVHAAADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAG-LERNRIRKHLLVFALAAPVMSMVTYLGLSKSSKEALSEVNATGVAMLFSAGTFLYVATVHVLPEV--GGI-----------------GHSHKPDATGGRGLSRLEVAALVLGCLIPLILSVGHQH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5BL29-1", "uniprot_id": "S39A9_DANRE", "id": "Q5BL29-1", "name": "Zinc transporter ZIP9", "aln": "-MDDFSSISLLSLSMLIGCYVAGTIPLAVNFSEEKLKLVTVLGAG---LLCGTALAVIIPEGVHALYEEMLEGVHNHGHGQVEAEVSEQKVAEGVVRPSGEHGHGHEQLHAYIGISLVLGFVFMLLVDQIGSAHMHSSDDPEAARAASS---------KITTTLGLVVHAAADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAG-LERNRIRKHLLVFALAAPVLAMVTYVGLSQSSKEALSDVNATGVAMLFSAGTFLYVATVHVLPEV--GGMG----------------GHSHSPGGSAGKGLSKLEVGALVLGCLIPLVLSIGHQH-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V4C6-1", "uniprot_id": "Q9V4C6_DROME", "id": "Q9V4C6-1", "name": "", "aln": "MAEETIILILLVLVMLVGSYLAGSIPMLMKLSEEKLKCVTVLGAG---LLVGTALVVIIPEGIRSLY------------------VGSGQSQKRTSVPEQ---PDYSQT---IGLSLVLGFVFMMLVD-------ISQRKSNVGSNKKN---------NATLTLGLVVHAAADGVALGAAATTSHQDVEIIVFLAIMLHKAPAAFGLVTFLLHEK-VDRHQIRRHLVLFSLSAPLMTILTYFGIGQEQKDTLNSVNATGIAMLFSAGTFLYVATVHVLPELTQGGFTKSDQHDYCLLEESRGVATNDINGSNSIQALKYSELVILICGALLPLIITFGHNH-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12067-1", "uniprot_id": "ATX2_YEAST", "id": "Q12067-1", "name": "Metal homeostasis factor ATX2", "aln": "--MKFLGVILLASFLLIATFLIGLIPLYYIDKQKSSIVTNQEGADSISDFTTNADTQTINDDVSSYRVKIAVLSQFGIGMLLGTSFMLVIPEGIKACVEHDGNVGVNLLIGFLGVYVLDRLVTLWVSRKQTVYTHDAVKFQSWKDIINHPRQIWMNLIQNNVVFALFIHGLSDGIALG--TTTNNDSLLIVVLIAIVIHKIPAVLSLTSLMVSRQNLMKWEVICNVFLFASSTPIGYIVLSL-LNLSHSPTMDWISGN--LLLMSGGSLLYASFTAFVGGD----------------------SHDHDLSVEQEVVLPHDESVYVLIGVCIPLVISYCISEE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ** :*:. :: * **: .:: .. **. : .* . : :.: : . . . :*: :: :* : : : . . : . .:.*.:*. :**:*** ::*.: .: ::*::**::** **.:.*.:::: : : .: ::.:*: ::* :: . :. . . ::. :... :*:*.*::**.: . .: . * * :. . ", "identical_positions": 36, "similar_positions": 104, "identity": "10.53%" }, { "cls_id": "homologset.agr.SGD:S000005611", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35777-1", "uniprot_id": "MAGT1_RAT", "id": "O35777-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1", "aln": "-----------MASPRWLWCVCATAAVTLLLVSKVPS-ASAQRKKEKVLVEKVIQLMEWTNQRPVIRMNGDKFRPLVKAPPRNYSVIVMFTALQLHRQCVVCKQADEEFQILANFWR------YSSAFTNRIFFAMVDFDEGS----DVFQMLNMNSAPTFINFPPKGKPKRAD---TYELQVRGFSAEQIARWIADRTDVNIRVIRPPNYAGPLMLGLLLAVIGGLVYLRRSNMEF--LFNKTGWAFAALCFVLAMTSGQMWNHIRGPPYAHKNPHTGHVNYIHGSSQAQFVAETHIVLLFNGGVTLGMVLLCE---------AAASDMDIGKRRMMCIAGIGLVVLFFSWMLSIFRSKYHGYPYSFLMS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQY5-1", "uniprot_id": "MAGT1_MOUSE", "id": "Q9CQY5-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1", "aln": "-----------MASPRWFWSVCAIAAVALLLVSKVPS-ASAQRKKEMVLSEKVSQLMEWANKRPVIRMNGDKFRRLVKAPPRNYSVVVMFTALQLHRQCVVCKQADEEFQILANSWR------YSNAFTNRIFFAMVDFDEGS----DVFQMLNMNSAPTFINFPPKGKPKRAD---TYELQVRGFSAEQIARWIADRTDVNIRVIRPPNYAGPLMLGLLLAVIGGLVYLRRSNMEF--LFNKTGWAFAALCFVLAMTSGQMWNHIRGPPYAHKNPHTGHVNYIHGSSQAQFVAETHIVLLFNGGVTLGMVLLCE---------AATSDMDIGKRRMMCIAGIGLVVLFFSWMLSIFRSKYHGYPYSFLMS-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0U3-1", "uniprot_id": "MAGT1_HUMAN", "id": "Q9H0U3-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1", "aln": "-----------MAARWRFWCVSVTMVVALLIVCDVPS-ASAQRKKEMVLSEKVSQLMEWTNKRPVIRMNGDKFRRLVKAPPRNYSVIVMFTALQLHRQCVVCKQADEEFQILANSWR------YSSAFTNRIFFAMVDFDEGS----DVFQMLNMNSAPTFINFPAKGKPKRGD---TYELQVRGFSAEQIARWIADRTDVNIRVIRPPNYAGPLMLGLLLAVIGGLVYLRRSNMEF--LFNKTGWAFAALCFVLAMTSGQMWNHIRGPPYAHKNPHTGHVNYIHGSSQAQFVAETHIVLLFNGGVTLGMVLLCE---------AATSDMDIGKRKIMCVAGIGLVVLFFSWMLSIFRSKYHGYPYSFLMS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZV50-1", "uniprot_id": "MAGT1_DANRE", "id": "Q7ZV50-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1", "aln": "-------------------MLHKLLIVVFLVVCLHDMRLNGQKKKETLLSEKVSQMMEWVSKRAVVRLNGEKFKRLVRAHPRNYSVIVMFTALQPQRQCGVCRQADEEYQILANSWR------YSSAFTNRIFFAMVDFDEGS----DVFQMLNMNSAPTFINFPAKGKPKRAD---TYELQVRGFAAEQLARWVADRTDVHIRVIRPPNYAGPLMLGLLLAFIGSLAYLRRNNLEF--LFNKNVWAFSALCFVLIMTSGQMWNHIRGPPYAHKNPNTGQVSYIHGSSQAQFVAETHIVLLFNAAVTIGMVLLHE---------AATSGLDIVKRKIMCVAGIGLVVLFFSWLLSVFRAKYHGYPYSFLFG-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q13454-1", "uniprot_id": "TUSC3_HUMAN", "id": "Q13454-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3", "aln": "MGARGAPSRRRQAGRRLRYLPTGSFPFLLLLLLLCIQLGGGQKKKENLLAEKVEQLMEWSSRRSIFRMNGDKFRKFIKAPPRNYSMIVMFTALQPQRQCSVCRQANEEYQILANSWR------YSSAFCNKLFFSMVDYDEGT----DVFQQLNMNSAPTFMHFPPKGRPKRAD---TFDLQRIGFAAEQLAKWIADRTDVHIRVFRPPNYSGTIALALLVSLVGGLLYLRRNNLEF--IYNKTGWAMVSLCIVFAMTSGQMWNHIRGPPYAHKNPHNGQVSYIHGSSQAQFVAESHIILVLNAAITMGMVLLNE---------AATSKGDVGKRRIICLVGLGLVVFFFSFLLSIFRSKYHGYPYSDLDFE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2KAE2-1", "uniprot_id": "A0A0G2KAE2_RAT", "id": "A0A0G2KAE2-1", "name": "", "aln": "MSARAAPSRRRQAGRRLRYLSTGSFPFLLLLLLLCIQLGGGQKKKENLLAEKVEQLMEWSSRRSIFRMNGDKFRKFVKAPPRNYSMIVMFTALQPQRQCSVCRQANEEYQILANSWR------YSSAFCNKLFFGMVDYDEGT----DVFQQLNMNSAPTFMHFPSKGRPKRAD---TFDLQRIGFAAEQLAKWIADRTDVHIRVFRPPNYSGTIALALLVSLVGGLLYLRRNNLEF--IYNKTGWAMVSLCIVFAMTSGQMWNHIRGPPYAHKNPHNGQVSYIHGSSQAQFVAESHIILVLNAAITMGMVLLNE---------AATSKGDVGKRRIICLVGLGLVVFFFSFLLSIFRSKYHGYPYSDLDIE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BTV1-1", "uniprot_id": "TUSC3_MOUSE", "id": "Q8BTV1-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3", "aln": "MSARAAPSRRRQAGRRLRYLPTGSFPFLLLLLLLCIQLGGGQKKKENLLAEKVEQLMEWSSRRSIFRMNGDKFRKFVKAPPRNYSMIVMFTALQPQRQCSVCRQANEEYQILANSWR------YSSAFCNKLFFGMVDYDEGT----DVFQQLNMNSAPTFMHFPSKGRPKRAD---TFDLQRIGFAAEQLAKWIADRTDVHIRVFRPPNYSGTIALALLVSLVGGLLYLRRNNLEF--IYNKTGWAMVSLCIVFAMTSGQMWNHIRGPPYAHKNPHNGQVSYIHGSSQAQFVAESHIILVLNAAITMGMVLLNE---------AATSKGDVGKRRIICLVGLGLVVFFFSFLLSIFRSKYHGYPYSFLIK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48439-1", "uniprot_id": "OST3_YEAST", "id": "P48439-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3", "aln": "-------------------------MNWLFLVSLVFFCGVSTHPALAMSSNRLLKLANKSPKK-IIPLKDSSFENILAPPHENAYIVALFTATAPEIGCSLCLELESEYDTIVASWFDDHPDAKSSNSDTSIFFTKVNLEDPSKTIPKAFQFFQLNNVPRLFIFKPNSPSILDHSVISISTDTGSERMKQIIQAIKQFSQVNDFSLHLPMDWTPIITSTIITFITVLLFKKQSKLMFSIISSRIIWATLSTFFIICMISAYMFNQIRNTQLAGVGPKGEVMYFLPNEFQHQFAIETQVMVLIYGTLAALVVVLVKGIQFLRSHLYPETKKAYFIDAILASFCALFIYVFFAALTTVFTIKSPAYPFPLLRLSAPFK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::: . : : ::: :: : :: :. ::...*. :: . .* ::.:*** . * :* : :.*:: :. * *. . :** *: :: : ..** :::*..* :: * .:. . . : . : . :*: : : : ::*: :: * .: . :::.: * : ::.:: * : .: ** : ::: * *. *:*:**.. * .*: : :: .. * **. *::::::: . :: :*:* : . : ::. :: .**: : ::* * .**:. * ", "identical_positions": 46, "similar_positions": 137, "identity": "12.23%" }, { "cls_id": "homologset.agr.SGD:S000005612", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3U7R1-1", "uniprot_id": "ESYT1_MOUSE", "id": "Q3U7R1-1", "name": "Extended synaptotagmin-1", "aln": "---------------------------------------------MEHSPEEGASP-------------------EPSGQPPATDSTRDGGSGV-------PPAGPGAASEALAVLTSFGRRLLVLVPVYLAGAAGLSVGFVLFGLALYLGWRRVRDGKERSLRAARQLLD--DEERITAETLYMSHRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYMEKLLAETVAP--AVRGAN-PHLQTFTFTRVELGEKPLRIIGVKVHPSQR-KDQILLDLNVSYVGDVQIDVEVKKYF-----------------CKAGVKGMQLHGVLRVILEPLTGDLPIVGAVSMFFIKRPTLDINWTGMTN------LLDIPGLSSLSDTMIMDSIAAFLVLPNRLLVPLVPDLQDVAQLRSPLPRGIIRIHLLAARGLSSKDKYVKGLIEGKSDPYALVRVG-TQTFCSRVIDEELNPHWGETYEVIVHEVPGQEIEVEVFDKDPDK-----DDFLGRMKLDVGKVLQA---GVLDNWYPLQGG-QGQVHLRLEWLSLLPDAEKLDQVLQWNRG--------------ITSRPEPPSAAILVVYLDRAQDLP--------------------------------------------------------LKKGNKEPNPMVQLSVQDVTRESKATYSTNSPVWEEAFRFFLQDPRSQELDVQVKDDSRALTLGALTLPLARLLTASELTLDQW--FQLSSSGPNSRLYMKLVMRILYLDYSEIRFPTVP---GAQDWDRESLETGSSVDAPPRPYHTTPNSHFGTENVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKVAGKSFRTHVVREDLNPRWNEVFEVIVTSIPGQELEIEVFDKDLDKDDFLGRYKVSLTTVLNSGFLDEWLTLEDVPSGRLHLRLERLTPRPTAAELEEVLQVNSLIQTQKSSELAAALLSVFLERAEDLPLRKGTKPPSPYATITVGETSHKTKTVSQSSAPVWEESASFLIRKPHAESLELQVRGEGTGTLGSVSLPLSELLQEDQLCLDHWFALS-GQGQVLMRAQLGILVSQHSGVEAHSHSYSHSHSSSSLNDEPEALGGPTHPASPVLEVRHRLTHG---DSPSEAPVGPLGQVKLTVWYHSD---------------EQKLISIIHSCRALRQNG-RDLPDPYVSVLLLPDKNRSTKRKTPQKKRTLNPEFNER-----------------------------------------------------------------------FEWDLPLDGTLRRKLDVSVKSNSSFMSRERELLGKVQLDLAEIDLS--QGAAQWYDLMDDRDKGGS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BSJ8-1", "uniprot_id": "ESYT1_HUMAN", "id": "Q9BSJ8-1", "name": "Extended synaptotagmin-1", "aln": "---------------------------------------------MERSPGEGPSPSPMDQPSA---------PSDPTDQPPAAHAKPDPGSGG-------QPAGPGAAGEALAVLTSFGRRLLVLIPVYLAGAVGLSVGFVLFGLALYLGWRRVRDEKERSLRAARQLLD--DEEQLTAKTLYMSHRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYMEKLLAETVAP--AVRGSN-PHLQTFTFTRVELGEKPLRIIGVKVHPGQR-KEQILLDLNISYVGDVQIDVEVKKYF-----------------CKAGVKGMQLHGVLRVILEPLIGDLPFVGAVSMFFIRRPTLDINWTGMTN------LLDIPGLSSLSDTMIMDSIAAFLVLPNRLLVPLVPDLQDVAQLRSPLPRGIIRIHLLAARGLSSKDKYVKGLIEGKSDPYALVRLG-TQTFCSRVIDEELNPQWGETYEVMVHEVPGQEIEVEVFDKDPDK-----DDFLGRMKLDVGKVLQA---SVLDDWFPLQGG-QGQVHLRLEWLSLLSDAEKLEQVLQWNWG--------------VSSRPDPPSAAILVVYLDRAQDLP--------------------------------------------------------LKKGNKEPNPMVQLSIQDVTQESKAVYSTNCPVWEEAFRFFLQDPQSQELDVQVKDDSRALTLGALTLPLARLLTAPELILDQW--FQLSSSGPNSRLYMKLVMRILYLDSSEICFPTVPGCPGAWDVDSENPQRGSSVDAPPRPCHTTPDSQFGTEHVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKLAGRSFRSHVVREDLNPRWNEVFEVIVTSVPGQELEVEVFDKDLDKDDFLGRCKVRLTTVLNSGFLDEWLTLEDVPSGRLHLRLERLTPRPTAAELEEVLQVNSLIQTQKSAELAAALLSIYMERAEDLPLRKGTKHLSPYATLTVGDSSHKTKTISQTSAPVWDESASFLIRKPHTESLELQVRGEGTGVLGSLSLPLSELLVADQLCLDRWFTLSSGQGQVLLRAQLGILVSQHSGVEAHSHSYSHS--SSSLSEEPELSGGPPHITSSAPELRQRLTHV---DSPLEAPAGPLGQVKLTLWYYSE---------------ERKLVSIVHGCRSLRQNG-RDPPDPYVSLLLLPDKNRGTKRRTSQKKRTLSPEFNER-----------------------------------------------------------------------FEWELPLDEAQRRKLDVSVKSNSSFMSRERELLGKVQLDLAETDLS--QGVARWYDLMDNKDKGSS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0FGR9-1", "uniprot_id": "ESYT3_HUMAN", "id": "A0FGR9-1", "name": "Extended synaptotagmin-3", "aln": "---------------------------------------------MRAEEPCAPG--------------------APS----ALGAQRTP-----------GPELRLSSQLLPELCTFVVRVLFYLGPVYLAGYLGLSITWLLLGALLWMWWRRNRRGKLGRLAAAFEFLD--NEREFISRELRGQH--LPAWIHFPDVERVEWANKIISQTWPYLSMIMESKFREKLEP--KIREKS-IHLRTFTFTKLYFGQKCPRVNGVKAHTNTCNRRRVTVDLQICYIGDCEISVELQK-------------------IQAGVNGIQLQGTLRVILEPLLVDKPFVGAVTVFFLQKPHLQINWTGLTN------LLDAPGINDVSDSLLEDLIATHLVLPNRVTVPVKKGLD-LTNLRFPLPCGVIRVHLLEAEQLAQKDNFLG--LRGKSDPYAKVSIG-LQHFRSRTIYRNLNPTWNEVFEFMVYEVPGQDLEVDLYDEDTDR-----DDFLGSLQICLGDVMTN---RVVDEWFVLNDTTSGRLHLRLEWLSLLTDQEVLT------------------------EDHGGLSTAILVVFLESACNLPRN------------------------------------PFDYLNGEYRAKKLSRFARNKVSKDPSSYVKLSVGKKTHTSKTCPHNKDPVWSQVFSFFVHNVATERLHLKVLDDDQECALGMLEVPLCQILPYADLTLEQR--FQLDHSGLDSLISMRLVLRFLQVEERE-----------------------------LGSPYTGPEALK-----------------------------KGPLLIKKVATNQGPKAQPQEEGP-----------------------------------------------------------------------------------------------------------------TDLPCPPDPASDTKDVSRSTTTTTSATTVAT-EPTSQETGPEPKGKDSAKRFCEPIGEKKS--------------------------PATIFLTVPGPHSPGPIKSPRP------MKCPASPFAWPPKRLAPSMSSLNSLASSCFDLADISLNI---EGGDLR-RRQLGEIQLTVRYVCL---------------RRCLSVLINGCRNLTPCT-SSGADPYVRVYLLPERKWACRKKTSVKRKTLEPLFDET-----------------------------------------------------------------------FEFFVPMEEVKKRSLDVAVKNSRPLGSHRRKELGKVLIDLSKEDLI--KGFSQWYELTPNGQPRS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZC04-1", "uniprot_id": "D3ZC04_RAT", "id": "D3ZC04-1", "name": "Extended synaptotagmin-3", "aln": "---------------------------------------------MQPEESCAGS--------------------APPGPDVPERRQRSP-----------DPEPRLSGQLLPELYSFVARVLFYLAPVYLAGYLGLSVTWLLLGALLWMWWRRNRRGKLGRLEAAFEFLE--HEREFISRELRGQH--LPAWIHFPDVERVEWANKIITQIWPYLSMIMENKIREKLEP--KIREKS-IHLRTFTFTKLYFGQKCPKVNGVKAHTDKCNRRKVTLDLQICYIGDCEISVELQK-------------------IRAGVNGVQLQGTLRVILEPLLVDKPFIGAVTVFFLQKPHLQINWTGLTN------LLDMPGINELSDSLLEDLIAAHLVLPNRVTVPVKKGLD-ITSLRVPLPCGVIRVHLLEAKKLAQKDNFLG--LGGKSDPYAKVSIG-LQQCRSRTVYKNLNPTWNEVFEFMVYEVPGQDLEVDLYDEDADR-----DDFLGSLQISLGDVMKN---RVVDEWFVLNDTTSGRLHLRLEWLSLLTDPEALE------------------------NDSG-LSTAILVVFLENACNLPRN------------------------------------PFDYLNGEYRAKKLSRFVKNKASRDPSSYVKLSVGKKTFTSKTCPHSKDPVWSQVFSFFVHSVAAEQLCLKVLDDELECALGVLEFPLCQILSCADLTLEQC--FQLDHSGLDSLISMRLVLRFLRVGERE-----------------------------LGSPYTGPDALK-----------------------------KGPLFVKKVDTNQGCKAPTLKEDL-----------------------------------------------------------------------------------------------------------------TDVTSILNPASYIKGASKSTDNISVATKAPEPKPEPQETGLEPKGKDGATGLCESLGRKKN--------------------------PATTFLTVPGPHSPGPIKSPRP------MSRPAFPFAWPLTRVAPSMSSLNSLASSCFDLTDVSFNT---ESGDCR-LRRLGEIQLTVRYVCL---------------RHCLRVLVNGCRNLTPCT-SSGADPYVRIYLLPERRWASRKKTSVKQKTLEPLFDET-----------------------------------------------------------------------FEFFVPMGEVQKRSLDVAVKNSRPLGSHRRKELGKVLIDLSKQDLI--KGFSQWYELTPDGQPRS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TZZ7-1", "uniprot_id": "ESYT2_MOUSE", "id": "Q3TZZ7-1", "name": "Extended synaptotagmin-2", "aln": "------------------------------------------------MSSAGGE--------------------GPEAGPGRAGGRSEP-----------EAPGSALSVDLPGLLGQLARSFALLLPVYALGYLGLSFSWVLLALGLLAWCRRSRGLKASRLCRALALLE--DEEQAVRLGVRACD--LPAWVHFPDTERAEWLNKTVKHMWPFICQFIEKLFRETIEP--AVRGAN-AHLSTFSFTKVDVGQQPLRVNGVKVYTENVDKRQIILDLQISFVGNCEIDLEIKRYF-----------------CRAGVKSIQIHGTMRVILEPLIGDMPLVGALSIFFLRKPLLEINWTGLTN------LLDIPGLNGLSDTIILDIISNYLVLPNRITVPLVSEVQ-IAQLRFPIPKGVLRIHFIEAQDLQGKDTYLKGLVKGKSDPYGIIRVG-NQIFQSKVIKENLSPKWNEVYEALVYEHPGQELEIELFDEDPDK-----DDFLGSLMIDLIEVEKE---RLLDEWFTLDEVPKGKLHLKLEWLTLMPDAANLDKVLADIRAD-------------KDQASDGLSSALLILYLDSARNLP-------------------------------------------------------SGKKINSNPNPLVQMSVGHKAQESKIRYKTSEPVWEENFTFFIHNPRRQDLEVEVKDEQHQCSLGSLRIPLSQLLTSDNMTINQR--FQLSNSGPNSTLKMKIALRVLHLEKQ------------------------------ERPPDYQHSAQV-----------------------------KRP-SVSKEGRKMPIKS--------------------------------------------------------------------------------------------------------------------------------QMSASPGTGGANTAPSTPVMGVDDKPAMEEKPQ----PPEAS--------------------------------------------PLGHRDLG--RSSSS------LLASPS--HIAAKEPTPSIASDISLPIATQELRQRLRQL---ENGTTLGQSPLGQIQLTIRHSSQ---------------RNKLIVVVHSCRNLIAFS-EDGSDPYVRMYLLPDKRRSGRRKTHVSKKTLNPVFDQS-----------------------------------------------------------------------FDFSVSLPEVQRRTLDVAVKNSGGFLSKDKGLLGKVLVVLASEELA--KGWTQWYDLTEDGTRPQVIT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZJ32-1", "uniprot_id": "D3ZJ32_RAT", "id": "D3ZJ32-1", "name": "Extended synaptotagmin-2", "aln": "------------------------------------------------MSSAGGE--------------------GPEAGTGRAGGRSEP-----------EAPGSALSVDLPGLLGQLARSFALLLPVYALGYLGLSFSWVLLALGLLAWCRRSRGLKASRLCRALALLE--DEEQAVRLGVRACD--LPAWVHFPDTERAEWLNKTVKHMWPFICQFIEKLFRETIEP--AVRGAN-AHLSTFSFTKVDVGHQPLRVNGVKVYTENVDKRQIILDLQISFVGNCEIDLEIKRYF-----------------CRAGVKSIQIHGTMRVILEPLIGDMPLVGALSIFFLRKPLLEINWTGLTN------LLDIPGLNGLSDTIILDIISNYLVLPNRITVPLVSEVQ-IAQLRFPIPKGVLRIHFIEAQDLQGKDTYLKGLVKGKSDPYGIIRVG-NQIFQSKVVKENLSPKWNEVYEALVYEHPGQELEIELFDEDPDK-----DDFLGSLMIDLIEVEKE---RLLDEWFTLDEVPKGKLHLKLEWLTLMPDAANLDKVLADIRAD-------------KDQANDGLSSALLILYLDSARNLP-------------------------------------------------------SGKKINSNPNPLVQMSVGHKAQESKIRYKTSEPVWEENFTFFIHNPKRQDLEVEVKDEQHQCSLGSLRIPLSQLLASDNMTINQR--FQLSNSGPNSTLKMKIALRVLHLEKQ------------------------------ERPPDYQHSAQV-----------------------------KRP-SVSKEGRKMPIKS--------------------------------------------------------------------------------------------------------------------------------QMSASPGTGGTNTAPSTPVMGVDDKPAMEEKPQ----PPEAS--------------------------------------------PLGQRDLG--RSSSS------LLASPS--HIAAKEPTPSIASDISLPIATQELRQRLRQL---ENGTTLGQSPLGQIQLTIRHSSQ---------------RNKLIVVVHSCRNLIAFS-EDGSDPYVRMYLLPDKRRSGRRKTHVSKKTLNPVFDQS-----------------------------------------------------------------------FDFSVSLPEVQRRTLDVAVKNSGGFLSKDKGLLGKVLVALASEELA--KGWTQWYDLTEDGTRPQVIT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0FGR8-1", "uniprot_id": "ESYT2_HUMAN", "id": "A0FGR8-1", "name": "Extended synaptotagmin-2", "aln": "MTANRDAALSSHRHPGCAQRPRTPTFASSSQRRSAFGFDDGNFPGLGERSHAPGSRLGARRRAKTARGLRGHRQRGAGAGLSRPGSARAPSPPRPGGP---ENPGGVLSVELPGLLAQLARSFALLLPVYALGYLGLSFSWVLLALALLAWCRRSRGLKALRLCRALALLE--DEERVVRLGVRACD--LPAWVHFPDTERAEWLNKTVKHMWPFICQFIEKLFRETIEP--AVRGAN-THLSTFSFTKVDVGQQPLRINGVKVYTENVDKRQIILDLQISFVGNCEIDLEIKRYF-----------------CRAGVKSIQIHGTMRVILEPLIGDMPLVGALSIFFLRKPLLEINWTGLTN------LLDVPGLNGLSDTIILDIISNYLVLPNRITVPLVSEVQ-IAQLRFPVPKGVLRIHFIEAQDLQGKDTYLKGLVKGKSDPYGIIRVG-NQIFQSRVIKENLSPKWNEVYEALVYEHPGQELEIELFDEDPDK-----DDFLGSLMIDLIEVEKE---RLLDEWFTLDEVPKGKLHLRLEWLTLMPNASNLDKVLTDIKAD-------------KDQANDGLSSALLILYLDSARNLP-------------------------------------------------------SGKKISSNPNPVVQMSVGHKAQESKIRYKTNEPVWEENFTFFIHNPKRQDLEVEVRDEQHQCSLGNLKVPLSQLLTSEDMTVSQR--FQLSNSGPNSTIKMKIALRVLHLEKR------------------------------ERPPDHQHSAQV-----------------------------KRP-SVSKEGRKTSIKS--------------------------------------------------------------------------------------------------------------------------------HMSGSPGPGGSNTAPSTPVIGGSDKPGMEEKAQ----PPEAG--------------------------------------------PQGLHDLG--RSSSS------LLASPG--HISVKEPTPSIASDISLPIATQELRQRLRQL---ENGTTLGQSPLGQIQLTIRHSSQ---------------RNKLIVVVHACRNLIAFS-EDGSDPYVRMYLLPDKRRSGRRKTHVSKKTLNPVFDQS-----------------------------------------------------------------------FDFSVSLPEVQRRTLDVAVKNSGGFLSKDKGLLGKVLVALASEELA--KGWTQWYDLTEDGTRPQAMT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BIQ8-1", "uniprot_id": "A0A8M2BIQ8_DANRE", "id": "A0A8M2BIQ8-1", "name": "", "aln": "--------------------------------------MSASVNGVEPKPAPAVS------------------QNGPGSPPQTPKDVTPPELELP------DEEPQSSVTEATQMGIKFAKTFLLIFPIYLLGYLEFSFSWVLIGLGLVFWLKRNQGSRFARVNQAMAFLE--QEERAVRQTIRSSE--LPPWVHFPDVERVEWLNKTVQQMWPYICQFVEKIFKETIEP--AVQGAN-THLSTFTFSKIDMGDKPLRVDGVKVYTENVDKRQIIMDLQINFVGNTEIDVDIKKYY-----------------CRAGIKSIQLNGVLRVIMEPLLGDMPLVGALSVFFLKKPFLDINWTGLTN------MLDIPGVNSLCDNVIQDIINGCLVNPNKITIPLADDAL-ISKLRFPMPRGILRVHFLEGQDLLSKDTYMGGLIKGKSDPYGVIQIN-NQLFRSKIIKDSLNPRWNEVYEAIVYDGQGQVVFIELFDEDTDH-----DDFLGSLTMEIDEIQKQ---QKVDEWFDLIGVPNGKLHVKAEWLSLHPTPDKLDEVLSSIKAD-------------KGQANDGLSSALLLVHLDSAKNLPGVFEGQVGSGCLRERRSAGLVFCENTSALYRTMFRNPLEFNSAGLKKGAVNKAVKSGKKVTSVPNPFVQFTVGHRSFESKTRFKTIEPVWEETFTFLIHNPKCQDLEVEVKDEKHECSLGTITLPLSQLLKEKQMTMSQR--FPLKNSGPGSTLKMKMALRILSLDKL------------------------------AAS-DKPSSAQV-----------------------------HRAGSVRKTSNATPQRP--------------------------------------------------------------------------------------------------------------------------------AVSEPAKTSKTQQPAPAPRTQPTPTPSPRVEPVTDRKPLEES--------------------------------------------PPHLAKSG--KSMSN------LAISGSNLHLNSKEQTPSIASDISNLAATQELQKTIQQL---HNGASPGFAPLGEIELTIRHSPQ---------------RNKLIVVVHKCRNLISAS-QNGSDPYVRLYLLPDKRRSGRRKTSTAKKTVNPIFDQT-----------------------------------------------------------------------FEFTVSIMELPRRTLDVAVKNGGGILAKHRGLLGKVIVEFNLEDPS--KNSTQWYELSVDGFKRPSP---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K6F9-1", "uniprot_id": "A0A0B4K6F9_DROME", "id": "A0A0B4K6F9-1", "name": "", "aln": "-------------------------------MSDNSPSVPLAEFTIPPDPTETEPFVPLVEVKKMN--------ESPVVTPTTPTGNGTPPTQTTNGNSIVATKSVSDDNSIFSVFYTLGKKVAIVGSIYLVGYMGWSVAWLIAPVILSVARDQLAKTSEKKRDIAKASAL--ASE---KDVILARIDELPAWVYFPDVERCEWLNKILKQVWPNANHFARTLVKETIEPNVALALAN-YKMHGFRFDRIILGTIPPRIGGVKIYDKNVDRNEIIMDLDLFYASDCDINFYLGG-------------------MKGGIKDFQIHGWVRVVMKPLIRSMPLVGGLQIFFLNNPNIDFNLVGVID------FMDMPGLSDLLRRIIVEQIGNVMVLPNKLPISLSEEVS-AVALKMPEPEGILRIHVVEAKDLMKKDISVLG--KGKSDPYAIINVG-AQEFKTQIIDNNVNPKWDYWCEACIFTTIGHYIGFSLWDYDQTMPGVQSDDVLGRASIDIASVIKK---GVVDSWLTLEDAKHGLLHVRLQWYKLTADPNDLQQILLET----------------QLLRVTSMSSAVLSVFIDSARHLK--------------------------------------------------------QARSSSKPDPYLVCSVNKQKQQTAMIMRDDSPVWEQGFTFLVSNPDNESLNIKIYDQKTGNDIGQYTYTLSTLLKQFNMEVIQQP-FQLQKSGPESKLYMSLSLRILKPGEID----------------------------------------------------------------------KDSDALEQVAALT----------------------------------------------------------------------------------------------------------------------------------------------RSSSVKTPDVAAVSPPAFKESQASSKRLSAESP-----------------------------------------------------ISEED--------------PVAATKISPAMSASTSSEKPISELATSVLTHRFPDSTSSPGEHGLGRMQLSIRYSAQ---------------RQKLDVTIHKIQKIPLRDPSNIPDPYVKLYLLPGRTKESKRKTSVIKDNCNPVYDAS-----------------------------------------------------------------------FEYLISIAELRQTELEVTVCTQKGFLSGGSPIIGMLKIPLDDAEITTQTGLNSWFDLQPEIRHE------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12466-1", "uniprot_id": "TCB1_YEAST", "id": "Q12466-1", "name": "Tricalbin-1", "aln": "-----------------MAKEDTGVTAPKKPETAQVANINGIDKLEPPKTKEETESSKSVSSEK---------AAHASDESFKRSIHEASYVGWKQIGGWEDKDELTLDDELMDMTRETFLDNIIPDSLYGDWYHSVAIFFIGGVASFALGHYKFSMGSAFFVIVITSLLYRTSAKKYRGSIRELVQKEFTVQKVENDYESLEWLNAFLDKYWPILEPSVSQLIVQQANEQMATNEAIPKFITQLWIDELTLGVKPPRVDLVKTF-QNTASDVVVMDWGISFTPHDLCDMSAKQVRNYVNELAVVKAKIFGITIPVSVSDIAFKAHARVKFK-LMTPFPHVETVNIQLLKVPDFDFVATLFGRSIFNWEILAIPGLMTLIQKMAKKYMGPILLPPFSLQLNIPQLLS-----GSNLSIGILEITVKNAKGLKRTSSILN----ESIDPYLSFEFNDISIAKTRTVRDTLNPVWDETLYVLLNSFTDP-LTISVYDKRAKLK----DKVLGRIQYNLNTLHDKTTQRNLKAQFLRNSKPVGELTFDLRFFPTLEEKKLPDGSVEELPDLNTGIAKVVVEEGSRFAEEEQKVTAYVEVYLNAKLVLTTG------------------------------------KATDTGTLKWNSDYEAVIADRRKTRYKFVVKDGKGEEIGSTIQTLNDLIDRSQVNKNLIPLKNQKGDIKITTYWRPVRLEIGSNSVAYTPPIGAIRVFIEKANDLRNLEKFGTIDPYCKVLVNGLSKGRTDFKSQTLN------------PVWNQVIYVAVTSPNQRITLQCMDVETVNKDRSLGEFNVNVQDLFKKDENDKYEETIDEKAKVGRLVMPKKKPKG------------------------------------------------------------------------------------------------TITYYTSFYPALPVLTLEEIQDLDKVNKKKKALELRKSAIDEKKISKEDKAKFDQEWNEVKELEDMYSNRQKLDLPELLQYNQGVLAVTVLNGELPDSGLYVQAFFDDNGHPRFVSPRIPSRIVKNGWSGDVIIKELDKSITTFRVAKNKNYNRVEKCVCEVELPTQELVKNCYYKPSILHLSGEGSAKLMLQISWFPIDTKQLPANDLITNSGDLTIMSRSAENLIASDLNGYSDPYLKYYINNEE--DCAYKTKVVKKTLNPKWNDEGTIQINNRLNDVLRIKVMDWDSTSADDTIGTAEIPLNKVKVEGTTELDVPVEGLENAGQDGGMLHLAFSFKPRYTISVSKREKKVGDIASKGLGTGLKAGTTVIGGGVGAIGKIKKGVFGGLGSLTNHKKNHEMGEEETKF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .:* :. :: : : . :. * * ** * : : ** . : : : : .: .* :: ** . : :* : : . .. .:... ::. ** :: * * : : : ::. * ::: . . :: **: : : . : :: * : : : . *::.: . .. * .. : . *** . .. . :: : :.* *. : . : ..::* *..** : : :. * : . .: :* : :.:: * : . . : . : . :: . : : :* . : : : : : . : :. * : : . :: * :* : * . . : . .***: : . :* : . .* :: : :.: : ::: :* : . . : : ", "identical_positions": 45, "similar_positions": 169, "identity": "3.28%" }, { "cls_id": "homologset.agr.SGD:S000005613", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WTR1-1", "uniprot_id": "TRPV2_MOUSE", "id": "Q9WTR1-1", "name": "Transient receptor potential cation channel subfamily V member 2", "aln": "---------------------------------------MTSASNPPAFR----------------LETSDGDEEGSAEVNK-------------GKNEP-------------------PPMESPFQGEDRNFSPQIKVN-------------------------LNYRKG-----LGPSQQDPNRFDR----DRLFSVVSRGVPEELTGLLEYLRRTSKY--------LTDSAYTEGSTGKTCLMKAVLNLQDGVNACILPLLQIDRDSGNPQPLVNAQCTDEFYRG-------------HSALHIAIEKRSLWCVKLLVENGANVHIRACGRFFQKHQG------------TCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDSLLQMGARLCPTVQLEDICNHQGLTPLKLAAKEGKIEIFRHILQREFSG-LYQP-------------LSRKFTEWCYGPVRVSLYDLSSVDSW---------EKNSVLEIIAFHCK-SPHRHRMVVLEP--------LNKLLQEKWDRLIPR-FFFNFACYLVYMIIFTIVAYHQPS--------------LEQPAIPSSKATF-----------------------------------GDSMLLLGHILILLGGIYLLLGQLW-YFWRRRL-FIWISFMDSYFEILFLVQALLTVLSQVLRFV----------------ETEWYLPLLVSSLVLGWLNLLYYTRGF--QHTGIYSVMIQKVILRDLLRFLLVYLVFL-----------FGFAVALVSLSREARSPKAPEDSNTTVTEKPTLGQEEEP--VPYGGILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTY--------------------VLLLNMLIALMSETVNSVATDSWS---IWKLQKAISVLEMENGYWWCRRKRHRA------------GRLLKVGTKGDGIPDERWCFRVEEVNWAAWEKTLP-TLSEDP-------------------SGAGITGYKKNP----TSKPGKNSASEEDHLPLQVLQSH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WUD2-1", "uniprot_id": "TRPV2_RAT", "id": "Q9WUD2-1", "name": "Transient receptor potential cation channel subfamily V member 2", "aln": "---------------------------------------MTSASSPPAFR----------------LETSDGDEEGNAEVNK-------------GKQEP-------------------PPMESPFQREDRNSSPQIKVN-------------------------LNFIKRPPKNTSAPSQQEPDRFDR----DRLFSVVSRGVPEELTGLLEYLRWNSKY--------LTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQG-------------HSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQG------------TCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSG-PYQP-------------LSRKFTEWCYGPVRVSLYDLSSVDSW---------EKNSVLEIIAFHCK-SPNRHRMVVLEP--------LNKLLQEKWDRLVSR-FFFNFACYLVYMFIFTVVAYHQPS--------------LDQPAIPSSKATF-----------------------------------GESMLLLGHILILLGGIYLLLGQLW-YFWRRRL-FIWISFMDSYFEILFLLQALLTVLSQVLRFM----------------ETEWYLPLLVLSLVLGWLNLLYYTRGF--QHTGIYSVMIQKVILRDLLRFLLVYLVFL-----------FGFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEP--APYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTY--------------------VLLLNMLIALMSETVNHVADNSWS---IWKLQKAISVLEMENGYWWCRRKKHRE------------GRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTLP-TLSEDP-------------------SGPGITGNKKNP----TSKPGKNSASEEDHLPLQVLQSP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5S1-1", "uniprot_id": "TRPV2_HUMAN", "id": "Q9Y5S1-1", "name": "Transient receptor potential cation channel subfamily V member 2", "aln": "---------------------------------------MTSPSSSPVFR----------------LETLDGGQEDGSEADR-------------GKLDFG---------------SGLPPMESQFQGEDRKFAPQIRVN-------------------------LNYRKG-----TGASQPDPNRFDR----DRLFNAVSRGVPEDLAGLPEYLSKTSKY--------LTDSEYTEGSTGKTCLMKAVLNLKDGVNACILPLLQIDRDSGNPQPLVNAQCTDDYYRG-------------HSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQG------------TCFYFGELPLSLAACTKQWDVVSYLLENPHQPASLQATDSQGNTVLHALVMISDNSAENIALVTSMYDGLLQAGARLCPTVQLEDIRNLQDLTPLKLAAKEGKIEIFRHILQREFSG-LSH--------------LSRKFTEWCYGPVRVSLYDLASVDSC---------EENSVLEIIAFHCK-SPHRHRMVVLEP--------LNKLLQAKWDLLIPK-FFLNFLCNLIYMFIFTAVAYHQPT--------------LKKQAAPHLKAEV-----------------------------------GNSMLLTGHILILLGGIYLLVGQLW-YFWRRHV-FIWISFIDSYFEILFLFQALLTVVSQVLCFL----------------AIEWYLPLLVSALVLGWLNLLYYTRGF--QHTGIYSVMIQKVILRDLLRFLLIYLVFL-----------FGFAVALVSLSQEAWRPEAPTGPNATESVQPMEGQEDEGNGAQYRGILEASLELFKFTIGMGELAFQEQLHFRGMVLLLLLAYVLLTY--------------------ILLLNMLIALMSETVNSVATDSWS---IWKLQKAISVLEMENGYWWCR-KKQRA------------GVMLTVGTKPDGSPDERWCFRVEEVNWASWEQTLP-TLCEDP-------------------SGAGVPRTLENPVLASPPKEDEDGASEENYVPVQLLQSN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q704Y3-1", "uniprot_id": "TRPV1_MOUSE", "id": "Q704Y3-1", "name": "Transient receptor potential cation channel subfamily V member 1", "aln": "--------------------------------MEKWASLDSDESEPPAQENS-------------CPDPPDRDPNSKPPPAKPHIFATRSRTRLFGKGDS----------------EEASPMDCPYEEGGLASCPIITVSSVVTL-------------QRSVDGPTCLRQTSQDSVSTGVETPPRLYDR----RSIFDAVAQSNCQELESLLSFLQKSKKR--------LTDSEFKDPETGKTCLLKAMLNLHNGQNDTIALLLDIARKTDSLKQFVNASYTDSYYKG-------------QTALHIAIERRNMALVTLLVENGADVQAAANGDFFKKTKGR-----------PGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTADNTKFVTNMYNEILILGAKLHPTLKLEELTNKKGLTPLALAASSGKIGVLAYILQREIHEPECRH-------------LSRKFTEWAYGPVHSSLYDLSCIDTC---------EKNSVLEVIAYSSSETPNRHDMLLVEP--------LNRLLQDKWDRFVKRIFYFNFFVYCLYMIIFTTAAYYRP---------------VEGLPPYKLNNTV-----------------------------------GDYFRVTGEILSVSGGVYFFFRGIQ-YFLQRRP-SLKSLFVDSYSEILFFVQSLFMLVSVVLYFS----------------HRKEYVASMVFSLAMGWTNMLYYTRGF--QQMGIYAVMIEKMILRDLCRFMFVYLVFL-----------FGFSTAVVTLIEDGKNNSLPVES----PPHKCRGSACRP-GNSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVFIILLLAYVILTY--------------------ILLLNMLIALMGETVNKIAQESKN---IWKLQRAITILDTEKSFLKCMRKAFRS------------GKLLQVGFTPDGKDDFRWCFRVDEVNWTTWNTNVG-IINEDPGNCEGVKRTLSFSLRSGRVSGRNWKNFALVPLLRDASTRDRHSTQPEEVQLKHYTGSLKPEDAEVFKDSMAPGEK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35433-1", "uniprot_id": "TRPV1_RAT", "id": "O35433-1", "name": "Transient receptor potential cation channel subfamily V member 1", "aln": "--------------------------------MEQRASLDSEESESPPQENS-------------CLDPPDRDPNCKPPPVKPHIFTTRSRTRLFGKGDS----------------EEASPLDCPYEEGGLASCPIITVSSVLTI-------------QRPGDGPASVRPSSQDSVSAG-EKPPRLYDR----RSIFDAVAQSNCQELESLLPFLQRSKKR--------LTDSEFKDPETGKTCLLKAMLNLHNGQNDTIALLLDVARKTDSLKQFVNASYTDSYYKG-------------QTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGR-----------PGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLAYILQREIHEPECRH-------------LSRKFTEWAYGPVHSSLYDLSCIDTC---------EKNSVLEVIAYSSSETPNRHDMLLVEP--------LNRLLQDKWDRFVKRIFYFNFFVYCLYMIIFTAAAYYRP---------------VEGLPPYKLKNTV-----------------------------------GDYFRVTGEILSVSGGVYFFFRGIQ-YFLQRRP-SLKSLFVDSYSEILFFVQSLFMLVSVVLYFS----------------QRKEYVASMVFSLAMGWTNMLYYTRGF--QQMGIYAVMIEKMILRDLCRFMFVYLVFL-----------FGFSTAVVTLIEDGKNNSLPMES----TPHKCRGSACKP-GNSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVFIILLLAYVILTY--------------------ILLLNMLIALMGETVNKIAQESKN---IWKLQRAITILDTEKSFLKCMRKAFRS------------GKLLQVGFTPDGKDDYRWCFRVDEVNWTTWNTNVG-IINEDPGNCEGVKRTLSFSLRSGRVSGRNWKNFALVPLLRDASTRDRHATQQEEVQLKHYTGSLKPEDAEVFKDSMVPGEK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NER1-1", "uniprot_id": "TRPV1_HUMAN", "id": "Q8NER1-1", "name": "Transient receptor potential cation channel subfamily V member 1", "aln": "--------------------------------MKKWSSTDLGAAADPLQKDT-------------CPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDS----------------EEAFPVDCPHEEGELDSCPTITVSPVITI-------------QRPGDGPTGARLLSQDSVAASTEKTLRLYDR----RSIFEAVAQNNCQDLESLLLFLQKSKKH--------LTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEIARQTDSLKELVNASYTDSYYKG-------------QTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGR-----------PGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQEPECRH-------------LSRKFTEWAYGPVHSSLYDLSCIDTC---------EKNSVLEVIAYSSSETPNRHDMLLVEP--------LNRLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRP---------------VDGLPPFKMEKT------------------------------------GDYFRVTGEILSVLGGVYFFFRGIQ-YFLQRRP-SMKTLFVDSYSEMLFFLQSLFMLATVVLYFS----------------HLKEYVASMVFSLALGWTNMLYYTRGF--QQMGIYAVMIEKMILRDLCRFMFVYIVFL-----------FGFSTAVVTLIEDGKNDSLPSES----TSHRWRGPACRPPDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVFIILLLAYVILTY--------------------ILLLNMLIALMGETVNKIAQESKN---IWKLQRAITILDTEKSFLKCMRKAFRS------------GKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVG-IINEDPGNCEGVKRTLSFSLRSSRVSGRHWKNFALVPLLREASARDRQSAQPEEVYLRQFSGSLKPEDAEVFKSPAASGEK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9EPK8-1", "uniprot_id": "TRPV4_MOUSE", "id": "Q9EPK8-1", "name": "Transient receptor potential cation channel subfamily V member 4", "aln": "------------------MADPGDGPRAAPGEVAEPPGDESGTSGGEAFPLSSLANLFEGEEGSSSLSPVDASRPAGPGDGRPNLRMKFQGAFRKGVPNPIDLLESTLYESSVVPGPKKAPMDSLFDYGTYRHHPSDNKR--------------------WRRKVVEKQPQSPKAPAPQPPPILKVFNR----PILFDIVSRGSTADLDGLLSFLLTHKKR--------LTDEEFREPSTGKTCLPKALLNLSNGRNDTIPVLLDIAERTGNMREFINSPFRDIYYRG-------------QTSLHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEG-----------GYFYFGELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCSRLFPDSNLETVLNNDGLSPLMMAAKTGKIGVFQHIIRREVTDEDTRH-------------LSRKFKDWAYGPVYSSLYDLSSLDTCG--------EEVSVLEILVYNSK-IENRHEMLAVEP--------INELLRDKWRKFGAVSFYINVVSYLCAMVIFTLTAYYQP---------------LEGTPPYPYRTT------------------------------------VDYLRLAGEVITLFTGVLFFFTSIKDLFTKKCP-GVNSLFVDGSFQLLYFIYSVLVVVSAALYLA----------------GIEAYLAVMVFALVLGWMNALYFTRGL--KLTGTYSIMIQKILFKDLFRFLLVYLLFM-----------IGYASALVTLLNPCTNMKVCDED------QSNCTVPTYPACRDSETFSAFLLDLFKLTIGMGDLEMLSSAKYPVVFILLLVTYIILTF--------------------VLLLNMLIALMGETVGQVSKESKH---IWKLQWATTILDIERSFPVFLRKAFRS------------GEMVTVGKSSDGTPDRRWCFRVDEVNWSHWNQNLG-IINEDPGKSE------IYQYYGFSHTVGRLRRDRWSSVVPRVVELNKNSSADEVVVPLDNLGNPNCDGHQQGYAPKWRTDDAPL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ERZ8-1", "uniprot_id": "TRPV4_RAT", "id": "Q9ERZ8-1", "name": "Transient receptor potential cation channel subfamily V member 4", "aln": "------------------MADPGDGPRAAPGDVAEPPGDESGTSGGEAFPLSSLANLFEGEEGSSSLSPVDASRPAGPGDGRPNLRMKFQGAFRKGVPNPIDLLESTLYESSVVPGPKKAPMDSLFDYGTYRHHPSDNKR--------------------WRRKVVEKQPQSPKAPAPQPPPILKVFNR----PILFDIVSRGSTADLDGLLSYLLTHKKR--------LTDEEFREPSTGKTCLPKALLNLSNGRNDTIPVLLDIAERTGNMREFINSPFRDIYYRG-------------QTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEG-----------GYFYFGELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCSRLFPDSNLETVLNNDGLSPLMMAAKTGKIGVFQHIIRREVTDEDTRH-------------LSRKFKDWAYGPVYSSLYDLSSLDTCG--------EEVSVLEILVYNSK-IENRHEMLAVEP--------INELLRDKWRKFGAVSFYINVVSYLCAMVIFTLTAYYQP---------------LEGTPPYPYRTT------------------------------------VDYLRLAGEVITLLTGVLFFFTSIKDLFMKKCP-GVNSLFVDGSFQLLYFIYSVLVVVSAALYLA----------------GIEAYLAVMVFALVLGWMNALYFTRGL--KLTGTYSIMIQKILFKDLFRFLLVYLLFM-----------IGYASALVTLLNPCTNMKVCNED------QSNCTVPSYPACRDSETFSAFLLDLFKLTIGMGDLEMLSSAKYPVVFILLLVTYIILTF--------------------VLLLNMLIALMGETVGQVSKESKH---IWKLQWATTILDIERSFPVFLRKAFRS------------GEMVTVGKSSDGTPDRRWCFRVDEVNWSHWNQNLG-IINEDPGKSE------IYQYYGFSHTMGRLRRDRWSSVVPRVVELNKNSGTDEVVVPLDNLGNPNCDGHQQGYAPKWRAEDAPL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HBA0-1", "uniprot_id": "TRPV4_HUMAN", "id": "Q9HBA0-1", "name": "Transient receptor potential cation channel subfamily V member 4", "aln": "------------------MADSSEGPRAGPGEVAELPGDESGTPGGEAFPLSSLANLFEGEDGSLSPSPADASRPAGPGDGRPNLRMKFQGAFRKGVPNPIDLLESTLYESSVVPGPKKAPMDSLFDYGTYRHHSSDNKR--------------------WRKKIIEKQPQSPKAPAPQPPPILKVFNR----PILFDIVSRGSTADLDGLLPFLLTHKKR--------LTDEEFREPSTGKTCLPKALLNLSNGRNDTIPVLLDIAERTGNMREFINSPFRDIYYRG-------------QTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEG-----------GYFYFGELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRREVTDEDTRH-------------LSRKFKDWAYGPVYSSLYDLSSLDTCG--------EEASVLEILVYNSK-IENRHEMLAVEP--------INELLRDKWRKFGAVSFYINVVSYLCAMVIFTLTAYYQP---------------LEGTPPYPYRTT------------------------------------VDYLRLAGEVITLFTGVLFFFTNIKDLFMKKCP-GVNSLFIDGSFQLLYFIYSVLVIVSAALYLA----------------GIEAYLAVMVFALVLGWMNALYFTRGL--KLTGTYSIMIQKILFKDLFRFLLVYLLFM-----------IGYASALVSLLNPCANMKVCNED------QTNCTVPTYPSCRDSETFSTFLLDLFKLTIGMGDLEMLSSTKYPVVFIILLVTYIILTF--------------------VLLLNMLIALMGETVGQVSKESKH---IWKLQWATTILDIERSFPVFLRKAFRS------------GEMVTVGKSSDGTPDRRWCFRVDEVNWSHWNQNLG-IINEDPGKNE------TYQYYGFSHTVGRLRRDRWSSVVPRVVELNKNSNPDEVVVPLDSMGNPRCDGHQQGYPRKWRTDDAPL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K424-1", "uniprot_id": "TRPV3_MOUSE", "id": "Q8K424-1", "name": "Transient receptor potential cation channel subfamily V member 3", "aln": "-------------------------MNAHSKEMAPLMGKRTTAPGGNPVVLT-------------EKRPADLTPTKKSAHFFLEIEGFEPNPTVTKTSPP----------------IFSKPMDSNIRQCLSGNCDDMDSP-------------------QSPQDDVTETPSNPNSPSANLAKEEQRQKKKRLKKRIFAAVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILDRFINAEYTEEAYEG-------------QTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQH-----------EGFYFGETPLALAACTNQPEIVQLLMEN--EQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSG----NWELETMRNNDGLTPLQLAAKMGKAEILKYILSREIKEKPLRS-------------LSRKFTDWAYGPVSSSLYDLTNVDTT---------TDNSVLEIIVYNTN-IDNRHEMLTLEP--------LHTLLHTKWKKFAKYMFFLSFCFYFFYNITLTLVSYYRPR--------------EDEDLPHPLALTHK----------------------------------MSWLQLLGRMFVLIWATCISVKEGIAIFLLRPS-DLQSILSDAWFHFVFFVQAVLVILSVFLYLF----------------AYKEYLACLVLAMALGWANMLYYTRGF--QSMGMYSVMIQKVILHDVLKFLFVYILFL-----------LGFGVALASLIEKCSKDKKDCSS--------------------YGSFSDAVLELFKLTIGLGDLNIQQNSTYPILFLFLLITYVILTF--------------------VLLLNMLIALMGETVENVSKESER---IWRLQRARTILEFEKMLPEWLRSRFRM------------GELCKVA-----DEDFRLCLRINEVKWTEWKTHVS-FLNEDP---------------------GPIRRTADLNKIQDSSRSNSKTTLYAFDELDEFPETSV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PU00-1", "uniprot_id": "E9PU00_RAT", "id": "E9PU00-1", "name": "Transient receptor potential cation channel subfamily V member 3", "aln": "-------------------------MNAHSKEMVPLMGKRTTAPGGNPAVLT-------------EKRPADLTPTKKSAHFFLEIEGFEPNPTVTKTSPP----------------IFSKPMDSNIRQCLSGNCDDMDSP-------------------QSPQDDVTETPSNPNSPSANLAKEEQRQKKKRLKKCIFAAVSEGCVRELRELLQDLQELCRRRRGLDASDFLMHKLTASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILDRFINAEYTEEAYEG-------------QTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQH-----------EGFYFGETPLALAACTNQPEIVQLLMEN--EQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSG----NWELETMRNNDGLTPLQLAAKMGKAEILKYILGREIKEKPLRS-------------LSRKFTDWAYGPVSSSLYDLTNVDTT---------TDNSVLEIIVYNTN-IDNRHEMLTLEP--------LHTLLHMKWKKFAKYMFFLSFCFYFFYNITLTLVSYYRPR--------------EDEALPHPLALTHK----------------------------------MSWLQLLGRMFVLIWAMCISVKEGIAIFLLRPS-DLQSILSDAWFHFVFFVQAVLVILSVFLYLF----------------AYKEYLACLVLAMALGWANMLYYTRGF--QSMGMYSVMIQKVILHDVLKFLFVYILFL-----------LGFGVALASLIEKCSKDKKDCSS--------------------YGSFSDAVLELFKLTIGLGDLNIQQNSTYPILFLFLLITYVILTF--------------------VLLLNMLIALMGETVENVSKESER---IWRLQRARTILEFEKMLPEWLRSRFRM------------GELCKVA-----DEDFRLCLRINEVKWTEWKTHVS-FLNEDP---------------------GPIRRTADSNKIQDSSRSNSKTTLYAFDELDEFPETSV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NET8-1", "uniprot_id": "TRPV3_HUMAN", "id": "Q8NET8-1", "name": "Transient receptor potential cation channel subfamily V member 3", "aln": "-------------------------MKAHPKEMVPLMGKRVAAPSGNPAILP-------------EKRPAEITPTKKSAHFFLEIEGFEPNPTVAKTSPP----------------VFSKPMDSNIRQCISGNCDDMDSP-------------------QSPQDDVTETPSNPNSPSAQLAKEEQRRKKRRLKKRIFAAVSEGCVEELVELLVELQELCRRRHDEDVPDFLMHKLTASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILGRFINAEYTEEAYEG-------------QTALNIAIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQH-----------EGFYFGETPLALAACTNQPEIVQLLMEH--EQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSG----NWELETTRNNDGLTPLQLAAKMGKAEILKYILSREIKEKRLRS-------------LSRKFTDWAYGPVSSSLYDLTNVDTT---------TDNSVLEITVYNTN-IDNRHEMLTLEP--------LHTLLHMKWKKFAKHMFFLSFCFYFFYNITLTLVSYYRPR--------------EEEAIPHPLALTHK----------------------------------MGWLQLLGRMFVLIWAMCISVKEGIAIFLLRPS-DLQSILSDAWFHFVFFIQAVLVILSVFLYLF----------------AYKEYLACLVLAMALGWANMLYYTRGF--QSMGMYSVMIQKVILHDVLKFLFVYIVFL-----------LGFGVALASLIEKCPKDNKDCSS--------------------YGSFSDAVLELFKLTIGLGDLNIQQNSKYPILFLFLLITYVILTF--------------------VLLLNMLIALMGETVENVSKESER---IWRLQRARTILEFEKMLPEWLRSRFRM------------GELCKVA-----EDDFRLCLRINEVKWTEWKTHVS-FLNEDP---------------------GPVRRT-DFNKIQDSSRNNSKTTLNAFEEVEEFPETSV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91WD2-1", "uniprot_id": "TRPV6_MOUSE", "id": "Q91WD2-1", "name": "Transient receptor potential cation channel subfamily V member 6", "aln": "------------------------------------------------------------------MGPLQREDRPALGGANVAPGSSPVGVWHQPQPPKE---------------PAFHPMGWSLPKEKGLILCLWNKFCR---------------------WFHRQESWAQSRDEQNLLQQKRIWES-----PLLLAAKENDVQALSKLLKFEGCEVHQ---------------RGAMGETALHIAALYDN---LEAAMVLMEAAP------ELVFEPMTSELYEG-------------QTALHIAVINQNVNLVRALLARGASVSARATGSVFH-YRPH-----------NLIYYGEHPLSFAACVGSEEIVRLLIEHG---ADIRAQDSLGNTVLHILILQP-----NKTFACQMYNLLLSYD-GGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQ------------------------KRKHIQWTYGPLTSTLYDLTEIDSSG--------DDQSLLELIVTTKK--REARQILDQTP--------VKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTNPRDNTLMQQKLLQEAYVTP----------------------------------KDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTILGGPFHVIIITYAFMVLVTMVMRLT----------------NVDGEVVPMSFALVLGWCNVMYFARGF--QMLGPFTIMIQKMIFGDLMRFCWLMAVVI-----------LGFASAFYIIFQTEDPDELGHFY----------------------DYPMALFSTFELFLTIIDGPANYDVDLPFMYSVTYAAFAIIAT--------------------LLMLNLLIAMMGDTHWRVAHERDE---LWRAQVVATTVMLERKLPRCLWPRSGIC-----------GREYGLG--------DRWFLRVEDRQDLNRQRIRR-YAQAFQQQDGL-YSEDLEKDSGEKLETARPFGAYLSFPTPSVSRSTSRSSTNWERLRQGALRKDLRGIINRGLEDGEGWEYQI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R186-1", "uniprot_id": "TRPV6_RAT", "id": "Q9R186-1", "name": "Transient receptor potential cation channel subfamily V member 6", "aln": "------------------------------------------------------------------MGPLQREGRPALGDANVAPGSSPGGVWHQPQPPKD---------------SAFHPMGWSLPKEKGLILCLWNKFCR---------------------WFHRRESWAQSRDEQNLLQQKRIWES-----PLLLAAKENNVQALIKLLKFEGCEVHQ---------------KGAMGETALHIAALYDN---LEAAMVLMEAAP------ELVFEPMTSELYEG-------------QTALHIAVINQNVNLVRALLARGASVSARATGSVFH-YRPH-----------NLIYYGEHPLSFAACVGSEEIVRLLIEHG---ADIRAQDSLGNTVLHILILQP-----NKTFACQMYNLLLSYD-GGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQ------------------------KRKHIQWTYGPLTSTLYDLTEIDSSG--------DDQSLLELIVTTKK--REARQILDQTP--------VKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAYVTP----------------------------------KDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTILGGPFHVIIVTYAFMVLVTMVMRLT----------------NSDGEVVPMSFALVLGWCNVMYFARGF--QMLGPFTIMIQKMIFGDLMRFCWLMAVVI-----------LGFASAFYIIFQTEDPDELGHFY----------------------DYPMALFSTFELFLTIIDGPANYDVDLPFMYSITYAAFAIIAT--------------------LLMLNLLIAMMGDTHWRVAHERDE---LWRAQVVATTVMLERKLPRCLWPRSGIC-----------GREYGLG--------DRWFLRVEDRQDLNRQRIRR-YAQAFQQQDDL-YSEDLEKDSGEKLEMARPFGAYLSFPTPSVSRSTSRSSTNWDRLRQGALRKDLQGIINRGLEDGEGWEYQI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H1D0-1", "uniprot_id": "TRPV6_HUMAN", "id": "Q9H1D0-1", "name": "Transient receptor potential cation channel subfamily V member 6", "aln": "------------------------------------------------------------------MGPLQGDGGPALGGADVAPRLSPVRVWPRPQAPKE---------------PALHPMGLSLPKEKGLILCLWSKFCR---------------------WFQRRESWAQSRDEQNLLQQKRIWES-----PLLLAAKDNDVQALNKLLKYEDCKVHQ---------------RGAMGETALHIAALYDN---LEAAMVLMEAAP------ELVFEPMTSELYEG-------------QTALHIAVVNQNMNLVRALLARRASVSARATGTAFR-RSPC-----------NLIYFGEHPLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILILQP-----NKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQ------------------------KRKHTQWTYGPLTSTLYDLTEIDSSG--------DEQSLLELIITTKK--REARQILDQTP--------VKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTP----------------------------------KDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTILGGPFHVLIITYAFMVLVTMVMRLI----------------SASGEVVPMSFALVLGWCNVMYFARGF--QMLGPFTIMIQKMIFGDLMRFCWLMAVVI-----------LGFASAFYIIFQTEDPEELGHFY----------------------DYPMALFSTFELFLTIIDGPANYNVDLPFMYSITYAAFAIIAT--------------------LLMLNLLIAMMGDTHWRVAHERDE---LWRAQIVATTVMLERKLPRCLWPRSGIC-----------GREYGLG--------DRWFLRVEDRQDLNRQRIQR-YAQAFHTRG----SEDLDKDSVEKLELGCPFSPHLSLPMPSVSRSTSRSSANWERLRQGTLRRDLRGIINRGLEDGESWEYQI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P69744-1", "uniprot_id": "TRPV5_MOUSE", "id": "P69744-1", "name": "Transient receptor potential cation channel subfamily V member 5", "aln": "-------------------------------------------------------------------------------------------------------------------------MG-----AKTPWIQLQKLLN----------------------WWVRDQDWNQHVDQLHMLQQKSIWES-----PLLRAAKENDMCTLKKLQHDQNCDFRQ---------------RGALGETALHVAALYDN---LDAAIMLMEAAP------YLVTESTLCEPFVG-------------QTALHIAVMNQNVNLVRALLARGASASARATGSAFH-RSSH-----------NLIYYGEHPLSFAACVGSEEIVRLLIEHG---ADIRAQDSLGNTVLHILVLQP-----NKTFACQMYNLLLSYDG-GDHLKSLELVPNNQGLTPFKLAGVEGNTVMFQHLMQ------------------------KRKRIQWSFGPLTSSLYDLTEIDSWG--------EELSFLELVVSSKK--KEARQILEQTP--------VKELVSLKWKKYGQPYFCLLGALYIFYMVCFTTCCVYRPLKFRDANRTHVRDNTIMEQKSLQEAYVTY----------------------------------QDKIRLVGELVTVIGAVIILLLEIPDIFRVGASRYFGQTVLGGPFHVIIITYASLVLLTMAMRLT----------------NVNGEVVPMSMALVLGWCSVMYFARGF--QMLGPFTIMIQKMIFGDLLRFCWLMAMVI-----------LGFASAFYIIFQTEDPDNLGEFS----------------------DYPTAMFSTFELFLTIIDGPANYRVDLPFMYSVTYATFAIIAT--------------------LLMLNLFIAMMGDTHWRVAQERDE---LWRAQVVATTVMLERKMPRFLWPRSGIC-----------GCEYGLG--------DRWFLRVEHHQEQNPYRVLR-YVEAFKSSDKEEVQEQLSEKQPSGTETGTLARGSVVLQTPPLSRTTSLSSN--SHRGWEILRRNTLGHLNLGLDPGEGDGEEIYQF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JIP0-1", "uniprot_id": "TRPV5_RAT", "id": "Q9JIP0-1", "name": "Transient receptor potential cation channel subfamily V member 5", "aln": "-------------------------------------------------------------------------------------------------------------------------MG-----VKKPWIQLQKRLN----------------------WWVREQDWNQHVDQLHMLQQKSIWES-----PLLRAAKENDMCTLKRLQHDQNCDFRQ---------------RGALGETALHVAALYDN---LDAAIMLMETAP------YLVTESTLCEPFVG-------------QTALHIAIMNQNVNLVRALLARGASASARATGSAFH-RSSH-----------NLIYYGEHPLSFAACVGSEEIVRLLIEHG---ADIRAQDSLGNTVLHILVLQP-----NKTFACQMYNLLLSHDG-GDHLKSLELVPNNQGLTPFKLAGVEGNTVMFQHLMQ------------------------KRKHIQWSLGPLTSSIYDLTEIDSWG--------EDLSFLELVVSSKK--KEARQILEQTP--------VKELVSLKWKKYGQPYFCLLGMLYIFYMICFTTCCVYRPLKFRDANRTHVRDNTVLEQKPLQEAYVTY----------------------------------QDKVRLVGELVTVIGAVVILLIEIPDIFRVGASRYFGHTVLGGPFHVIIITYASLVLLIMVMRLT----------------SMNGEVVPISMALVLGWCSVMYFSRGF--QMLGPFTIMIQKMIFGDLLRFCWLMAMVI-----------LGFASAFYIIFQTEDPESLGEFS----------------------DYPTAMFSTFELFLTIIDGPANYSVDLPFMYHLTYFAFAIIAT--------------------LLMLNLFIAMMGDTHWRVAQERDE---LWRAQVVATTVMLERKMPRFLWPRSGIC-----------GCEYGLG--------DRWFLRVEHHQEQNPYRVLR-YVEAFKSSDKEEVQEQLSEKQPSGTETGTLARGSVVLQTPPLSRTTSLSSN--SHRGWEILRRNTLGHLNLGQDLGEGDGEEIYHF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQA5-1", "uniprot_id": "TRPV5_HUMAN", "id": "Q9NQA5-1", "name": "Transient receptor potential cation channel subfamily V member 5", "aln": "-------------------------------------------------------------------------------------------------------------------------MGGFLPKAEGPGSQLQKLLPS---------------------FLVREQDWDQHLDKLHMLQQKRILES-----PLLRASKENDLSVLRQLLLDCTCDVRQ---------------RGALGETALHIAALYDN---LEAALVLMEAAP------ELVFEPTTCEAFAG-------------QTALHIAVVNQNVNLVRALLTRRASVSARATGTAFR-HSPR-----------NLIYFGEHPLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILILQP-----NKTFACQMYNLLLSYDGHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQ------------------------KRRHIQWTYGPLTSILYDLTEIDSWG--------EELSFLELVVSSDK--REARQILEQTP--------VKELVSFKWNKYGRPYFCILAALYLLYMICFTTCCVYRPLKFRGGNRTHSRDITILQQKLLQEAYETR----------------------------------EDIIRLVGELVSIVGAVIILLLEIPDIFRVGASRYFGKTILGGPFHVIIITYASLVLVTMVMRLT----------------NTNGEVVPMSFALVLGWCSVMYFTRGF--QMLGPFTIMIQKMIFGDLMRFCWLMAVVI-----------LGFASAFYIIFQTEDPTSLGQFY----------------------DYPMALFTTFELFLTVIDAPANYDVDLPFMFSIVNFAFTIIAT--------------------LLMLNLFIAMMGDTHWRVAQERDE---LWRAQVVATTVMLERKLPRCLWPRSGIC-----------GCEFGLG--------DRWFLRVENHNDQNPLRVLR-YVEVFKNSDKEDDQEHPSEKQPSGAESGTLARASLALPTSSLSRTASQSS---SHRGWEILRQNTLGHLNLGLNLSEGDGEEVYHF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3W0-1", "uniprot_id": "Q9W3W0_DROME", "id": "Q9W3W0-1", "name": "", "aln": "--------------------------------MKFLLKKCLR------------------------KKAPEMKPGAILDAVISQSSATACKCLLYKLADYK---------------RGGDLIDAINSGGLIAVEQLIREQFG---------------------VFMYNDGKGQVINRAEFLRWKYRDHT---EVTIPIEASLSIHDPLGKWEDHKACWQMQ--------------YRGALGESLLHVLIICDSKVHTKLARVLLRVFP------NLALDVMEGEEYLG-------------ASALHLSIAYSNNELVADLIEAGADIHQRAIGSFFLPRDQQRANPAKSTDYEGLAYMGEYPLAWAACCANESVYNLLVDCG---SDPDAQDSFGNMILHMVVVCD---------KLDMFGYALRHP----KTPAKNGIVNQTGLTPLTLACKLGRAEVFREMLELS------------------------AREFWRYSNITCSGYPLNALDTLLP---DGRTNWNSALFIILNGTK--PEHLDMLDGGI--------IQRLLEEKWKTFAQNQFLKRLLILSTHLLCLSVSVYLRPAHDGEAEDEDSEGSDASAAALLDIQSDEGDSGGG-------------------------DYNAQTVARYCAEFATLVGVLSYVIFQQGDEIKNQGLSAFLKQLSHAPAKAIFLFSNLLILACIPFRLIG---------------DTDTEEAILIFAVPGSWFLLMFFAGAI--RLTGPFVTMIYSMITGDMFTFGIIYCIVL-----------CGFSQAFYFLYKGHPQVQSTMFN----------------------TYTSTWMALFQTTLGDYNYPDLNQTTYPNLSKTVFVIFMIFVP--------------------ILLLNMLIAMMGNTYVTVIEQSEK---EWMKQWAKIVVTLERAVPQADAKGYLEAYS--IPLGPSDDSGFEVRGVMVIKSKSKTRAKQRKGAVSNWKRVGR-VTLTALKKRGMTGEEMRRLMWGRASISSPVKVTKQKLKDPYNLHTDSDFTNAMDMLTFASNPASSNGVTLRSVTAPPPAPPAPDPFRELIMMSDQRPETHDPHYFAGLQQLANKAFDLVEQTMKTQPQAPVAKKVDPLPVASVAKASPAAPATQATATAAAASDLMAMPLPISNLSNLFQDPKDIVDPKKLEEFMAMLAEVETEESDSGGPILGKLSLAKRTHNALSKAEIRRDQQGFEGHSHGQFQPMSSVWAPPGLDVDTGFHFDEAVAEEVLTIEQEAEVETEDGNGGQDSEDIPTAEEVHATMKQFHLRKCQPAQDEAARRAKSARVRRRNKVSPEQSDDPDERSQRGRSAYTRRTQSPPDPLEPWSTRELQDINKILARK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0AC58GIR7-1", "uniprot_id": "A0AC58GIR7_DANRE", "id": "A0AC58GIR7-1", "name": "", "aln": "-------------------MSQQYFRRTENFLYRDRIPLRIVRSESELSPLEKAYLWAVEKGDYGSVKQALIEAEIYFKININCIDPLGRTALLIAIENEN-------------LEIIELLLSFNVYVGDALLHAIRKEVVG------------------AVELLLNHKKPSGGMQVPPILLDKQFSDFTPDITPIILAAHTNNYEIIKMLVQKGVSMPQP-----HQVRCNCMECVSSSDVDSLRHSRSRLNIYRALASPSLVALSSEDPFLTAFQLSWELQELSKV-------------ENEFKSEYEELSQQCKQFAKDLLDQTRSSRELELILNYKDDINLLEDEGINDLARLKLAIKYHQKEFVAQPNCQQLLASRWYDEFPGWRRRHWASKFMTCIFIGLLFPFFSLFYLIAPKSHYGLFIRKPFIKFICHTASYLTFLFLLLLASQHVNRNLLDQDENSDCKNENLRQN------------LAPTTVEWMILPWVLGFVWAEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVALSK--------YNNQCRDEWDMWHPALVGEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYESDGK--TSNNVTCKGIRCSEQNNAFTTMFETLQSLFWSIFGLVALHVTNVDAKHDFTEFVGATMFGTYSIISLVVLLNMLIAMMNN------------SYQHIADHADIEWKFARTKLWMSYFEEGG--TLPPPFNVVPSPKSAWYLIRWIKTHCFKIKQRKRTETLGSLGVRGHFLLMLYSFIFHYMLTNFLFTEYYIYINNAFGFHYHIIKQSVLKKAIQLFSFVQIRAAENVRTNRQYQEVLRNLVKRYVAARIRDAKKEEGLTED-------NFKELKQDISSFRYEVMGMMKGTKTGMSTSKGNTAESSLVYPENALKCNSTSTGSTLKGKMRLQSITNTMIQEGGPKAWKPTGCSNLADSSVPNKNISHQLN-CKGPNNPGEMYSVSEEAGESESEEQGDGKQAENLDCKKKKNQNKETEKDGVNNDVEEDEELTYMRYMCEEEMNEGNEGETSRL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9R283-1", "uniprot_id": "TRPC2_RAT", "id": "Q9R283-1", "name": "Short transient receptor potential channel 2", "aln": "MLMSLTDSKEGKNRSGVRMFKDDDFLIPASGESWDRLRLTCSQPFTRHQSFGLAFLRVRSSLDSLSDPVKDPSSPGSSGLNQNSSDKLESDPSPWLTNPSIRRTFFPDPQTSTKEISALKGMLKQLQPGPLGRAARMVLSAAHKAPPASVVSPNNSHGEPDSSHPERAEPRAEEPNRKNNASRGKRRKVQEQRRPLSSSSSQPNRRATGRTKQRQQRPQAKSDGSGVQATGQCPICTGSFSIEALPRHAATCGESSPPQPASPTSLSSSESVLRCLHVALTPVPLIPKPNWTEIVNKKLKFPPTLLRAIQEGQLGLVQQLLESGSDPSGAGPGGPLRNVEESED--RSWREALNLAIRLGHEVITDVLLANVKFDFRQIHEALLVAVDTNQPAVVRRLLARLEREKGRKVDTKSFSLAFFDSSIDGSRFAPGVTPLTLACQKDLYEIAQLLMDQGHTIARPHPVSCACLECSNARRYDLLKFSLSRINTYRGIASRAHLSLASEDAMLAAFQLSRELRRLARKEPEFKPQYIALESLCQDYGFELLGMCRNQSEVTAVLNDLGEDSETEPEAEGLGQAFEEGIPNLARLRLAVNYNQKQFVAHPICQQVLSSIWCGNLAGWRGSTTIWKLFVAFLIFLTMPFLCIGYWLAPKSRLGRLLKIPVLKFLLHSASYLWFLIFLLGESLVMETQLSTFKGRSQSVWETSLHMIWVTGFLWFECKEVWIEGLRSYLLDWWNFLDVVILSLYLASFALRLLLAGLAYMHCRDASDSSTCRYFTTAERSEWRTEDPQFLAEVLFAVTS--------MLSFTRLAYILPAHESLGTLQISIGKMIDDMIRFMFILMIILTAFLCGLNNIYVPYQETEKLGNFNETFQFLFWTMFGMEEHSVVDMPQFLVPEFVGRAMYGIFTIVMVIVLLNMLIAMITNSFQKIEDDADVEWKFARSKLYLSYFREGLTLPVPFNILPSPK-----------AAFYLLRRIFRFICCGSSCCKAKKSDYPPIPTFTNPGARAGPGEGEHVSYRLRVIKALVQRYIETARREFEETRRKDLGNRLTELTKTVSRLQSEVASVQKTVAAGGALRPPDGASILSRYITRVRNSFQNLGPPAPDTPAELTMPGIVETEVSLEDSLDATGEAGTPASGESSSSSSAHVLVHREQEAEGAGDLPLGEDLETKGES----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12324-1", "uniprot_id": "YVC1_YEAST", "id": "Q12324-1", "name": "Calcium channel YVC1", "aln": "--------------------------------------------------------------------------------------------------------------------MVSANGDLHLPISNEQCMPENNGS-------------------------LGFEAPTPRQILRVTLNLKYLIDK---VVPIVYDPNDIVCDHSEILSPKVVKLAYE-------------------ACGGNPKDKANKRKYQSVIIFSLLKVCEWYSILATMEVHNAKLYETRN--------------------LASQQLCKLLIEREETRDLQFLFMQLLLRRYVIN------------ENDEDQEPLNALELATDMHCTTVIGSSGFQRCLKWIWRGWIVQNGLDPTTFIKDDSLAEVSLISHFNPVRLKAPVYQNYLQMIFSFLFLGLYTLVVNGKDSERVQSFDLLES-------------------------IFYVFNTGFILDELTKLYYIGYAH-------LSFWNLFNDTTYLIITFAMGFRAMSVTP-------LNAKYSSEDWDKISYRVLSCAAPFVWSRLLLYLESQRFIG----------------IMLVILKHMMKES----------------------------------IVFFFLLFLIMIGFTQGFLGLDSADGKRDITGPILGNLTITVLGLGSFDVFEEFAPPYAAILYYG-----------------YYFIVSVILLNILIALYSTAYQKVID--NADDEYMALMSQKTLRYIRAPDEDVYVSP-----------LNLIEVFMTPIFRILPPKRAKDLS--------------------YTVMTIVYSPFLLLISVKETREARRIKYNRMKRLNDDANEYDTP-----------------------WDLTDGYLDDDDGLFSDNRNS-------GMRATQLKNSRSLKLQRTAEQED-----------------------------VHFKVPKKWYKNVKKCSPSFEQYDN-------------------DDTEDDAGEDKDEVKELTKKVENLTAVITDLLEKLDIKDKKE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . : . . : . : . . . . : . . : . . : : . . : . . ", "identical_positions": 0, "similar_positions": 27, "identity": "0.0%" }, { "cls_id": "homologset.agr.SGD:S000005615", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61020-1", "uniprot_id": "RAB5B_HUMAN", "id": "P61020-1", "name": "Ras-related protein Rab-5B", "aln": "---------MTSRS-TARPNGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLAN---KRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLP-KSEPQNLGGAAGR---SRGVDLHEQSQ-QNKSQCCSN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61021-1", "uniprot_id": "RAB5B_MOUSE", "id": "P61021-1", "name": "Ras-related protein Rab-5B", "aln": "---------MTSRS-TARPNGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLAN---KRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLP-KSEPQNLGGAAGR---SRGVDLHEQSQ-QNKSQCCSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1L1J8-1", "uniprot_id": "A1L1J8_RAT", "id": "A1L1J8-1", "name": "small monomeric GTPase", "aln": "---------MTSRS-TARPNGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLAN---KRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLP-KSEPQNPGGAAGR---SRGVDLHEQAQ-QNKSQCCSN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35278-1", "uniprot_id": "RAB5C_MOUSE", "id": "P35278-1", "name": "Ras-related protein Rab-5C", "aln": "---------MAGRGGAARPNGPAAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLAS---KRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLP-KNEPQNAAGAPGR---TRGVDLQESNP-ASRSQCCSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0BNK1-1", "uniprot_id": "B0BNK1_RAT", "id": "B0BNK1-1", "name": "small monomeric GTPase", "aln": "---------MAGRGGAARPNGPAAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLAS---KRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLP-KNEPQNAAGAPGR---NRGVDLQESNP-ASRSQCCSN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51148-1", "uniprot_id": "RAB5C_HUMAN", "id": "P51148-1", "name": "Ras-related protein Rab-5C", "aln": "---------MAGRGGAARPNGPAAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLAS---KRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLP-KNEPQNATGAPGR---NRGVDLQENNP-ASRSQCCSN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CQD1-1", "uniprot_id": "RAB5A_MOUSE", "id": "Q9CQD1-1", "name": "Ras-related protein Rab-5A", "aln": "---------MANRG-ATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKADLAN---KRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLP-KNEPQNPGANSAR---GRGVDLTEPAQ-PARSQCCSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RC99-1", "uniprot_id": "RAB5A_RAT", "id": "M0RC99-1", "name": "Ras-related protein Rab-5A", "aln": "---------MANRG-ATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFSRAKNWVKELQRQASPNIVIALSGNKADLAN---KRAVDFQEAQSYADDNSLLFMETSAKTPMNVNEIFMAIAKKLP-KNEPQNPGANSAR---GRGVDLTEPAQ-PARSQCCSN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20339-1", "uniprot_id": "RAB5A_HUMAN", "id": "P20339-1", "name": "Ras-related protein Rab-5A", "aln": "---------MASRG-ATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKADLAN---KRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLP-KNEPQNPGANSAR---GRGVDLTEPTQ-PTRNQCCSN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TXV7-1", "uniprot_id": "A0AB32TXV7_DANRE", "id": "A0AB32TXV7-1", "name": "small monomeric GTPase", "aln": "---------MSTRG-TGRANGNLPQTKICQFKLVLLGDMAVGKSSLVLRFVKGQFDEFQETTIGAAFLAQSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVFDITKPETFERAKAWVKELQRQASPNIVIALAGNKADLAD---KRLVEYEEAQTYAEDTGLLFMETSAKTAMNVNELFLAIAKKMP-KTDTQNP-MHAVR---HRGVNLQDPDA-QSTRSCCGN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3I2-1", "uniprot_id": "RAB5_DROME", "id": "Q9V3I2-1", "name": "Ras-related protein Rab5", "aln": "MATTPRSGGASGTGTAQRPNG-TSQNKSCQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTICIEDTVVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDIQNQDSFQRAKTWVKELHKQASPNIVIALAGNKADLSN---IRVVEFDEAKQYAEENGLLFMETSAKTGMNVNDIFLAIAKKLP-KNDGANNQGTSIR---PTGTETNRP-----TNNCCK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36017-1", "uniprot_id": "VPS21_YEAST", "id": "P36017-1", "name": "Vacuolar protein sorting-associated protein 21", "aln": "-----------------------MNTSVTSIKLVLLGEAAVGKSSIVLRFVSNDFAENKEPTIGAAFLTQRVTINEHTVKFEIWDTAGQERFASLAPMYYRNAQAALVVYDVTKPQSFIKARHWVKELHEQASKDIIIALVGNKIDMLQEGGERKVAREEGEKLAEEKGLLFFETSAKTGENVNDVFLGIGEKIPLKTAEEQNSASNERESNNQRVDLNAANDGTSANSACSC", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .:******: ******:*****..:* * :*.*******:* : ::: .*************: ********.****:**:*: : ::* :*: *****:.*** .*:*** *** *: . * * :*.: *::..***:****** ***::*:.*.:*:* *. : * .: ..* ", "identical_positions": 97, "similar_positions": 54, "identity": "41.63%" }, { "cls_id": "homologset.agr.SGD:S000005616", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UV70-1", "uniprot_id": "PDP1_MOUSE", "id": "Q3UV70-1", "name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial", "aln": "-MPAPTQLFFPLVRNCELSRIYGTACYCHHKHLCCSPPYIPQNRLRYTPHPAYATFCRPRENWWQYTQGRRYASTPQK---FYLTPPQVNSILKANEYSFKVPEFDG-KNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETL-LEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLN---TGESADIDVKEALINAFKRLDNDISLEAQVGDPNSFLNY--LVLRVAFSGATACVAHVDGVD--LHVANTGDSRAMLGVQE-EDGSWSAVTLSNDHNAQNERELERLKLEHPKNEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVT--LGQMHGLLTER--------------RAKMSSVFEDQNAATHLIRHAVGNNEFGAVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQEQ----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88483-1", "uniprot_id": "PDP1_RAT", "id": "O88483-1", "name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial", "aln": "-MPAPTQLFFPLVRNCELSRIYGTACYCHHKHLCCSPPYIPQNRLRYTPHPAYATFCRPRENWWQYTQGRRYASTPQK---FYLTPPQVNSILKANEYSFKVPEFDG-KNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETL-LEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLN---TGESADIDVKEALINAFKRLDNDISLEAQVGDPNSFLNY--LVLRVAFSGATACVAHVDGVD--LHVANTGDSRAMLGVQE-EDGSWSAVTLSNDHNAQNERELERLKLEHPKNEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVT--LGQMHGLLTER--------------RAKMSSVFEDQNAATHLIRHAVGNNEFGAVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQEQ----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P0J1-1", "uniprot_id": "PDP1_HUMAN", "id": "Q9P0J1-1", "name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial", "aln": "-MPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCSSSYIPQSRLRYTPHPAYATFCRPKENWWQYTQGRRYASTPQK---FYLTPPQVNSILKANEYSFKVPEFDG-KNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETL-LEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLN---TGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNY--LVLRVAFSGATACVAHVDGVD--LHVANTGDSRAMLGVQE-EDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVT--LGQMHGLLTER--------------RTKMSSVFEDQNAATHLIRHAVGNNEFGTVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQE-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q504M2-1", "uniprot_id": "PDP2_MOUSE", "id": "Q504M2-1", "name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial", "aln": "MSSTVSYWIFNSARNRIALLRGGRRLYSRAATSRNLLKWRPFSPALASSALKCGSPPGG----FALRKAYRHTSTEEEDFHLQLSPEQVSDLLRAGESSHKVLDFNN-GVPNSVLRFESNQLAANSPVEDRQGVATCVQTNGMMFGIFDGHGGHACAQAVSERLFYYMAVSLMSHQTL-EQMEEATENMKPLLPILRWLKHPGDSIYKDVTSVHLDHLRVYWQELLD-----LHMEMGLSIEEALMYSFQRLDSDISLEIQAPLEDEVTRN--LSLQVAFSGATACMAHVNGVH--LHVANAGDCRAILGVQE-ENGAWSCLPLTCDHNAWNEAELSRLKREHPESEDRTLIIDDRLLGVLMPCRAFGDVQLKWSKELQRNVLARG-FDTEALNIYQFTPPHYYTPPYLTAKPEVTYHRLRRQDKFLVLASDGLWDMLGNEDVVRLVVGHLSKVGRHKPD-LDQRPAN--LGLMQSLLLQR--------------KASGLHAA-DQNTATHLIRHAIGSNEYGEMEPERLAAMLTLPEDVARMYRDDITVMVVFFNSDSIDTYCKEG-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88484-1", "uniprot_id": "PDP2_RAT", "id": "O88484-1", "name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial", "aln": "MSSTASYRIFNFARNRIAVLRGGRRLYSRAATSRNQVKWRLFSP--ASLAVNDSSPHGG----FALRKAYRHTSTEEEDFHLQLSPEQVSDLLRAGESSHKVLDFNS-GVPNSVLRFESNQLAANSPVEDRQGVASCVQTRGTMFGIFDGHGGHACAQAVSERLFYYMAVSLMSHKTL-EQMEEAMENMKPLLPILQWLKHPGDSIYKDITSVHLDHLRVYWQELLD-----LHMETGLSTEEALMYSFQRLDSDISLEIQAPLEDEVTKN--LSLQVAFSGATACMAHVDGVH--LHIANAGDCRAILGVQG-DNGAWSCLPLTCDHNAWNEAELSRLKREHPESEDRTLIIDDRLLGVLLPCRAFGDVQLKWSKELQRNVLERG-FDTEALNIYQFTPPHYHTPPYLTAKPEVTYHRLRPQDKFLVLASDGLWDMLDNEDVVRLVVGHLSKVGHQKPA-LDQRPAN--LGHMQSLLLQR--------------KASGLHAA-DQNAATHLIRHAIGSNEYGEMEPERLAAMLTLPEDVARMYRDDITVMVVFFNSESIDTYFKEG-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P2J9-1", "uniprot_id": "PDP2_HUMAN", "id": "Q9P2J9-1", "name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial", "aln": "MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSR--VPPTLN-SSPCGG----FTLCKAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLES-RVPNSVLRFESNQLAANSPVEDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTL-EHMEGAMESMKPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLD-----LHMEMGLSIEEALMYSFQRLDSDISLEIQAPLEDEVTRN--LSLQVAFSGATACMAHVDGIH--LHVANAGDCRAILGVQE-DNGMWSCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERG-FNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSNEDVVRLVVGHLAEADWHKTD-LAQRPAN--LGLMQSLLLQR--------------KASGLHEA-DQNAATRLIRHAIGNNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P8M8-1", "uniprot_id": "A0A8M1P8M8_DANRE", "id": "A0A8M1P8M8-1", "name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial", "aln": "MSGYLRSALLLGTR--------GRHLSSSFAASQHVLPDVACRALLFSSPARSFSSRGGRSDGSSGQEGENRLHPPRHEMDFQMSRLQINAVLRANEQSVRVPEFDGRGGPSPVLRFESNQLPANTPLEDRRSSASSLQTRSMLFGVFDGHGGHACAQAVSERLPYYISVAMMAESVL-EDLEAAMETSRPVPPILQWYKHHNDYNYRESAALYVDHLRVFWQELLAS----EEHGDGMRPADALSYAFQRLDTDLSLEAQVPLANDLMRN--TALQAAFAGCTACVAHVGPEG--VHVANAGDCRAVLGVQE-TDGSWSALPLTKDHNAANVAEMERVWRQHPASERQTVVVDDRLLGVLMPLRAFGDVRFKWSRELQQSVLENGDSDLEALNIYQYAPPNYLTPPYLEVTPEVTHHRLRPQDRFLILASDGLWDEMSNDEAVRLVAEHLTGVHLQAP--VSARQLN--LGQMHQLLLRR--------------RARATPAL-DLNAATHLIRHALGTNEYGEMDQERLATMLALPSDLARMYRDDITVTVIYFNPNFNKNNNKEH-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3Q1-1", "uniprot_id": "Q9W3Q1_DROME", "id": "Q9W3Q1-1", "name": "", "aln": "--------MFKFVLN------------DAASYVRSNVREFSLNALRLLPQLP------------------------------QLSPYDVNLVLRENEFVYNFP-VDG-----VIRSYETNQLGSNWPCEDSRTEASFLHRNGFICGIFDGHAGAACGQVVSKRLLRYVSAATLPRQVLREQMKQGADSQ----SFLKCHNDNVDFVS-MIKPMYEASFLKYVNQLLET--------PQRDVSSELVNAFLQLDEEISQEALTS--NDVR-----TMNVALSGAVACLVHIEGLQ--MHVASTGDCGAVLGVLDPQTQQWHSKKLNIEHNADNMSEVRRILAEHPKEEHETVIRNGRLLSQLAPLRAFGDFRYKWSQEIMQ-------QKVLPMFGVQAMAPNYYTPPYLTARPDVQQHELGPNDKFLVIASDGLWDFLPPSEVVSLVGEHINSKKILEPMRLPEGDTT--LQEISQQLAER--------------KAGLTRKPVDQNAATHLIRHALGGTDYG-IEHSKISYYLTLPRDAVRLYRDDITITVIYFNSEHIAKLHSDVDQTEVTAPVA-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12511-1", "uniprot_id": "PDP1_YEAST", "id": "Q12511-1", "name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial", "aln": "MSPLTRTVAIKKTVKVLSKCQSGREYTQKFLQRAYSTSHANSTYYSRTKLFISSHSKALNIALLSGSLLLTYSYYSPKKILSLDTINGIKDYSTNTSGNINMPSPNP--KGTETQKSQRSQNDQSVLILNDSKIEAKLHDREESHFVNRGTGIFRYDVAQLPSNHPIEDDHVEQIITIPIESEDGKSIEKDLYFFGIFDGHGGPFTSEKLSKDLVRYVAYQLGQVYDQNKTVFHSDPNQLIDSAISKGFLKLDNDLVIESFRKLFQDPNNTNIANTLPAISGSCALLSLYNSTNSILKVAVTGDSRALICGLD-NEGNWTVKSLSTDQTGDNLDEVRRIRKEHPGEPN--VIRNGRILGSLQPSRAFGDYRYKIKEVDGKPLSDLP---EVAKLYFRREPRDFKTPPYVTAEPVITSAKIGENTKFMVMGSDGLFELLTNEEIASLVIRWMDKNMNLAPVKAEPGKLPKVIDVSEDKEAQRPAFRYKDNNSSSPSGSNPEYLIEDKNVATHLIRNALS----AGGRKEYVSALVSIPSPMSRRYRDDLTVTVAFFGDSGTPSIVSNATSIVMNPEATTKPKPRL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :. . .. : : .* . : : :: . : * . . .: . : . . : . . :: . : .* :** :: * :. *::*. * : :::* :**. *:: * *. ::.. * *: *: :** . :: :.*:*. * * ***** : * . : : . .: ****: . * : .: : :*:::.:***:: : .: . :* : . : .* : * *.**:***:*:. . . :: :::* * ****:*: * *. . ", "identical_positions": 58, "similar_positions": 111, "identity": "9.93%" }, { "cls_id": "homologset.agr.SGD:S000005617", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TIV5-1", "uniprot_id": "ZC3HF_MOUSE", "id": "Q3TIV5-1", "name": "Zinc finger CCCH domain-containing protein 15", "aln": "MPPKKQAQAGGSKKAEQKKKEKIIEDKTFGLKNK-KGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKKDDKKKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSVYIDARDEE-LEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCRHFLEAIENNKYGWFWVCPGGGDNCMYRHALPPGFVLKK-DKKKEEK-----EDEISLEDLIERERSALG-PNVTKITLESFLAWKKRKRQEKIDKLEQDMERRKADFKAGKALVISGREVFEFRPELVNDDDEEADDTRYIQGTG----GDEVDDSMGVNDIDISLY--VPRDVEETGITVASVERFSTYAP---DKDENKLSEASGGLAENGERSDLDEDSGGGGQENGSIDAVPVDENLFTGEDLDELEEELNTLDLEE----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6U6G5-1", "uniprot_id": "ZC3HF_RAT", "id": "Q6U6G5-1", "name": "Zinc finger CCCH domain-containing protein 15", "aln": "MPPKKQAQAGGSKKAEQKKKEKIIEDKTFGLKNK-KGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKKDDKKKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSVYIDARDEE-LEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCRHFLEAIENNKYGWFWVCPGGGDNCMYRHALPPGFVLKK-DKKKEEK-----EDEISLEDLIERERSALG-PNVTKITLESFLAWKKRKRQEKIDKLEQDMERRKADFKAGKALVISGREVFEFRPELVNDDDEEADDTRYIQGTG----GDEVDDSVGVNDIDLSLY--VPRDVEETGITVASLERFSTYAS---DKDENKLSEASGGLAENGERSDLDEDSGGGGQENGSIDAVPVDENLFTGEDLDELEEELNTLDLEE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4AA59-1", "uniprot_id": "D4AA59_RAT", "id": "D4AA59-1", "name": "Zinc finger CCCH domain-containing protein 15", "aln": "MPPKKQAQARGSKKAEQKKKEKIIKEKNFELKNK-KVAKQQKFIKAVIHQVTFGQQNPRQVAQNEAEKKLKKDDKKKELQELNELFKQVVTAQKISKGANPKSVVCAFFKQGQCTKGDKCKFFHDLTLERKCEKQSVYIDARDEE-LEKDTADNWNEKRLEEVVNKRHGEAEKKKSKTQIVCRHFLEAIENNKYRWFWVCLGGEDNSMYRHALPPGFVLKK-DKKKEEK-----ENEISLDDLIERERSAPV-PNVTKITLESFLAWKKRKRQEKIDKLEQDMERQKDYFKAGKALVTSGREVFEFHPELVNDDDVEADDTRYIQRTE----GDEVDDSMGVNDIDLSLY--IPRDVEETGITMASLERFSTYAS---DKDENKLSEASGGLAENGERSDLDKDSGGEEQENGSIDAVPVDENLFTGEDLDELEEELNTLDLEE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WU90-1", "uniprot_id": "ZC3HF_HUMAN", "id": "Q8WU90-1", "name": "Zinc finger CCCH domain-containing protein 15", "aln": "MPPKKQAQAGGSKKAEQKKKEKIIEDKTFGLKNK-KGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKKDDKKKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSVYIDARDEE-LEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCKHFLEAIENNKYGWFWVCPGGGDICMYRHALPPGFVLKK-DKKKEEK-----EDEISLEDLIERERSALG-PNVTKITLESFLAWKKRKRQEKIDKLEQDMERRKADFKAGKALVISGREVFEFRPELVNDDDEEADDTRYTQGTG----GDEVDDSVSVNDIDLSLY--IPRDVDETGITVASLERFSTYTS---DKDENKLSEASGGRAENGERSDLEEDNEREGTENGAIDAVPVDENLFTGEDLDELEEELNTLDLEE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803J8-1", "uniprot_id": "ZC3HF_DANRE", "id": "Q803J8-1", "name": "Zinc finger CCCH domain-containing protein 15", "aln": "MPPKKPAPAAANKKTQEKKKEKIIEDKTFGLKNK-KGAKQQKFIKAVTQQVKFGQQNARQIAAAESEKTKKKDDKKKELSELNELFKPVVAAQKVSKGVDPKSVLCAFFKQGQCTKGDKCKFSHDLSLERKCEKRSLYVDGRDDELLEKDTMENWDEKKLEEVVNKKHGEAEKKKAKTQIVCKYFLDAIENNKYGWFWVCPGGGDNCMYRHALPVGFVLKK-DKKNEEKN----EEEISLEDLIETERSLLG-ANVTRITLETFLAWKKRKRQEKLAKAEQDMERKKADFKAGRALGVSGREVFEFRPELVDDDDEEADDTKYAEEDYNYGMSNQVEDTEEVQDIDIARF--IPKEVDNAGITVASADRFTAKAPPTNDIDDNKLSEASGGTMENGEHS--EDQTLEDGETNEESEAVPVDENLFTGEDLDELEEELNTLDLDE----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7JWR9-1", "uniprot_id": "ZC3HF_DROME", "id": "Q7JWR9-1", "name": "Zinc finger CCCH domain-containing protein 15 homolog", "aln": "MPPKK-APPGPSKKTEQKKKEKVIEDKTFGLKNK-KGNKQQKFIQQVQKQVQSGGQHPR---QDGDKRKEEKEKKLAEQREMALIFKP-VQTQKVEKGTDPKSVVCAFFKQGTCTKGDKCKFSHDLSQENKVEKRSIYVDMRDED----DPMTNWDDAKLKEVVEKKS-SGEKQRPTTDIICKFFLEAVEKSKYGWFWECPNGG-KCIYRHALPAGYVLKR-DKKKEEK-----PTEISLVDLIEKERAALG-PNQTRVTLESFLAWKKRKIAEKKAKLAAEEERKKSDFSKGKQFGISGREMFSFNPDLVDDGPMEEGDAAFDVYNR----EDDDDNAVEFKELDLAALSLAAKEVDGSG-TIASTNRLLDQAT-----EAAKTAAAEDAAAD-------EDGPSSSAPAN---DAAPINKDLFV-----DLAGELDDLDLDDEDDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12000-1", "uniprot_id": "TMA46_YEAST", "id": "Q12000-1", "name": "Translation machinery-associated protein 46", "aln": "MPPKK------GKQAQAAGKKKDNVDKTFGMKNKNRSTKVQKYIKQVQSQSDPKKEEMR------LKKLEEKKRREAEEAERRALFNP-VADQRVRAGVDPKSMVCALFKLGNCNKGAKCKFSHDLNVGRRMEKKDLYQDTRSEK--ENDTMDNWDEEKLRKVILSKHGNPKT---TTDKVCKYFIEAVENGKYGWFWICPNGGDKCMYRHSLPEGFVLKTNEQKRLERESLEKQPKITLEEFIETERGKLDKSKLTPITIANFAQWKKDHVIAKINAEKKLSSKRKP----------TGREIILK---------MSAENKSFETDNA-----DMPDDVTQGSAWDLTEFTDALKKADHQ------------------------------------------DDGGIKDYGDGSNPTFDIKK--------------ANSATLA-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** .*::: *:* :*.* :*** : * **:*: * * :. * :: :*. : * * :*: * *:: *.:***::**:** * *.** **** ***. .: **:.:* * *.:. *. **:: :*.:*: .: . :. .*: :*:.*::*:*:.** *** * .* .:***:** *:*** ::*. *: :*:* ::** **. .: * :*: .* *** : * .::* :***:: . : : : :: . *:: :..: . : : :.: : * ", "identical_positions": 97, "similar_positions": 105, "identity": "21.65%" }, { "cls_id": "homologset.agr.SGD:S000005619", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KB74-1", "uniprot_id": "A0A0G2KB74_RAT", "id": "A0A0G2KB74-1", "name": "", "aln": "MADRG---------CPLEAAPLPAEVLESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQ----------------------------------------------------------------------------------------------------------------------------------------DVHTEAVQAALAKYKER-KMP--MPSKRRSALVHSS--VETYTPP------------DTSSASEDEGSLRRPGRLTS-TLLQSHSGIEPWLDRVIQGSSTSSSASSTSSHPGGRPAAAP--------------------SASTALAGLTAHAHI---------------------------------------------DPHSAPPDVTTGLVEHS--HFERPQMASVRGVPRGHGRN-MLETADG-----------VPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLE-VQQPDPNQPKPEGEQMAVLKGEPLSVGTSGPPTLLAALQLWGTTQPKAPCLTALDTSGKAICTLTYGKLWSRSLKLAYTLLSKLTSK--NEPLLNPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGSQHVGFLLGSCGVTLALTTDACQKGLPK-APTGEVATFKGWPPLAWLVIDGKHLTKPPKDWYP-LAQDTGSRTAYIEYKTSKDGSTVGVTVPHSSLLAQCQALTQVCGYTEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVISIPYALMKVNPLSWIQK--VCSYKARAALVKSRDMHWSLLAQRGQRDVCLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRP-PDLGGPPP---RKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGASVCVVKVDGVPYLCKTDEIGEICVSSVATGTAYYGLLGITKNVFETVP--------------VTADGVPVSDRPFTRTGLLGFIGPENLVFVVGKLDGLTVVGARRHNADDIVATALAVEPMKFVYRG---------------------------------------------RIAVFSVTVLHDDRIVLVAEQRPDSSEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLG-GIHISETKQRFLEGTLHPCNVLMCPHTCVTN-LPKPRQKQP-------------------EVGPASMIVGNLVAGKRIAQASGRELAHLEDSDQAR--------KFLFLADVLQWRAHTTPDHPLFLLLNAKGTVTSTATCIQLHKR-----------AERVAAALMEKGRLDAGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTLPTVKMIVEVSKSACVLSTQAITRLLKSKEAAAAVDVRTWPTILDTDDIPKKKVASIFRPPSPDVLAYLDFSVSTTGILAG------------------VKMSHAATSALCRSIKLQCELYPSRQIAICLDPYCGLGFALWCLCSVYSGHQSVLVPPLELESNVSLWLSAVSQYKARVTFCSYSVMEMCTKGLGAQTGALRMKGVNLS----------------CVRTCMVVAEERPRISLTQSFSKLFKDLGLPARAVSTTFGCRVNVAICLQ----------GTTGPDPTTVYVDMRALRHDRVRLVER---GSPHSLPLMESGKILPGVKVIIAHTETKGPLGDSHLGEIWVSSPHNATGYYTVYG------EEALHADHFSARLSFGDT-QTIWARTGYLGFLRRTELTDAS----------------------------------------------------GERHDALYVVGSLDETLELRGMRYHPIDIETSVIRAHRSIAECAVFTWTNLLVVVVELDGLEQDALD-LVALVTNVVLEEHYLVVGVVVIVDPGVIPINSR-------------------GEKQRMHLRDGFLADQLDPIYVAYNM-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BWT5-1", "uniprot_id": "DIP2A_MOUSE", "id": "Q8BWT5-1", "name": "Disco-interacting protein 2 homolog A", "aln": "MADRG---------CPLEAAPLPAEVLESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQ----------------------------------------------------------------------------------------------------------------------------------------DVHTEAVQAALAKYKER-KMP--MPSKRRSALVHSS--VETYTPP------------DTSSASEDEGSLRRPGRLTS-TLLQSHSGIEPWLDRVIQGSSTSSSASSTSSHPGGRPAAAP--------------------SASTALAGLTAHAHI---------------------------------------------DLHSAPPDVTTGLVEHS--SYERPQMASVRGIPRGHGRN-VLETADG-----------VPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLE-VQQPDPNQPKPEGDQMAVLKGEPLSVGTNGPLSLLAALQLWGTTQPKAPCLTALDTAGKATCTLTYGKLWSRSLKLAYTLLNKLTSK--NEPLLNPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVTLALTTDACQKGLPK-APTGEVATFKGWPPLAWLVIDGKHLTRPPKDWYP-LAQDTGSRTAYIEYKTSKEGSTVGVTVSHSSLLAQCQALTQACGYTEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVITIPYALMKVNPLSWIQK--VCSYKARAALVKSRDMHWSLLAQRGQRDVCLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRP-PDLGGPPP---RKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGASVCVVKVDGAPYLCKTDEIGEICVNSVATGTAYYGLLGITKNTFETVP--------------VTADGVPVSDRPFTRTGLLGFIGPDNLVFVVGKLDGLMVVGVRRHNADDIVATALAVEPMKFVYRG---------------------------------------------RIAVFSVTVLHDDRIVLVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLG-GIHISETKQRFLEGTLHPCNVLMCPHTCVTN-LPKPRQKQP-------------------EVGPASMIVGNLVAGKRIAQASGRELAHLEDSDQAR--------KFLFLADVLQWRAHTTPDHPLFLLLNAKGTVTSTATCIQLHKR-----------AERVAAALMEKGRLDAGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTLPTVKMIVEVSKSACVLSTQAITRLLKSKEAAAAVDVRTWPTILDTDDIPKKKVASIFRPPSPDVLAYLDFSVSTTGILAG------------------VKMSHAATSALCRSIKLQCELYPSRQIAICLDPYCGLGFALWCLCSVYSGHQSVLVPPLELESNVSLWLSAVSQYKARVTFCSYSVMEMCTKGLGAQTGALRMKGVNLS----------------CVRTCMVVAEERPRISLTQSFSKLFKDLGLPARAVSTTFGCRVNVAICLQ----------GTTGPDPTTVYVDMRALRHDRVRLVER---GSPHSLPLMESGKILPGVKVIIAHTETKGPLGDSHLGEIWVSSPHNATGYYTVYG------EETLHADHFSARLSFGDT-QTIWARTGYLGFLRRTELTDAS----------------------------------------------------GERHDALYVVGSLDETLELRGMRYHPIDIETSVIRAHRSIAECAVFTWTNLLVVVVELDGLEQDALD-LVALVTNVVLEEHYLVVGVVVIVDPGVIPINSR-------------------GEKQRMHLRDGFLADQLDPIYVAYNM-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14689-1", "uniprot_id": "DIP2A_HUMAN", "id": "Q14689-1", "name": "Disco-interacting protein 2 homolog A", "aln": "MADRG---------CPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGID----------------------------------------------------------PSLQAENRIPGPSQTTAAAP--------------------------------------KQQKSRPTASRDERFRSDVHTEAVQAALAKYKER-KMP--MPSKRRSVLVHSS--VETYTPP------------DTSSASEDEGSLRRPGRLTS-TPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSA------------AATPGAAATTALAGLEAHTHI---------------------------------------------DLHSAPPDVTTGLVEHS--YFERPQVASVRSVPRGCSGS-MLETADG-----------VPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLE-VQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSK--NEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPK-AQTGEVAAFKGWPPLSWLVIDGKHLAKPPKDWHP-LAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQK--VCFYKARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRP-PDLGGPPP---RKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVP--------------VTTGGAPIFDRPFTRTGLLGFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRG---------------------------------------------RIAVFSVTVLHDDRIVLVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLG-GIHISETKQRFLEGTLHPCNVLMCPHTCVTN-LPKPRQKQP-------------------EVGPASMIVGNLVAGKRIAQASGRELAHLEDSDQAR--------KFLFLADVLQWRAHTTPDHPLFLLLNAKGTVTSTATCVQLHKR-----------AERVAAALMEKGRLSVGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTLPTVKMIVEVSKSACVLTTQAVTRLLRSKEAAAAVDIRTWPTILDTDDIPKKKIASVFRPPSPDVLAYLDFSVSTTGILAG------------------VKMSHAATSALCRSIKLQCELYPSRQIAICLDPYCGLGFALWCLCSVYSGHQSVLVPPLELESNVSLWLSAVSQYKARVTFCSYSVMEMCTKGLGAQTGVLRMKGVNLS----------------CVRTCMVVAEERPRIALTQSFSKLFKDLGLPARAVSTTFGCRVNVAICLQ----------GTAGPDPTTVYVDMRALRHDRVRLVER---GSPHSLPLMESGKILPGVKVIIAHTETKGPLGDSHLGEIWVSSPHNATGYYTVYG------EEALHADHFSARLSFGDT-QTIWARTGYLGFLRRTELTDAS----------------------------------------------------GGRHDALYVVGSLDETLELRGMRYHPIDIETSVIRAHRSIAECAVFTWTNLLVVVVELDGLEQDALD-LVALVTNVVLEEHYLVVGVVVIVDPGVIPINSR-------------------GEKQRMHLRDGFLADQLDPIYVAYNM-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AVP4-1", "uniprot_id": "A0A8M3AVP4_DANRE", "id": "A0A8M3AVP4-1", "name": "", "aln": "MAERGSGVLMMLLEPPALAMTLPAEVRERLAELELELSEGDITQKGYEKKRGKLLAPYIPQIQGVD----------------------------------------------------------PSLQIDHRIQSSAPAAHPAS--------------------------------------KHNKPRLANSRDERFRSDLHTEAVQAALAKYKER-KMP--MPSKRRSVLVQSS--VEACTPP------------DTSSASEDEGSLRRTGRFASSSPYAAQASVEHWFNRVIQGSSTSSSASSTSSHPGGRAQHCTN---------------TSSASAATVLADLMAHTHI---------------------------------------------DQHCAPPDVTGLLERSL--HAERPQVASVRGLPRGYTHSSLMETADGSVRADEEAVDGVPVNSRVSSKIQQLLNTLKRPKRPPLREFFLDDFEELLD-VQHPDPQQPKPEGGEMRPLSGDPPVVSSNRPSSLLGSLHRWGNTQAKSPCLTSLDNTGKPLYTLTYGKLWTRSQKLAFTLLNKLSSR--NEPLLRPGDRVALVFPNNDPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGGQQVGFLLGSCGVTLALTTDACQKGLPK-AQTGEVVTFKGWPRLLWFVTDGKHVVKPPKDWHP-PIRDASNEIAYIEYKTGKEGSTMGVTVSHSAMLAHCHALTQACGYTEGEIITNVLDFKRDAGLWHGVLTSVMNRMHVISIPYSLMKVNPLSWIQK--VHTYKARVAVVKSRDMHWSLLAQRDQRDISLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSSEALTVAIRRP-PETGVPPP---GKAVLSMSGLSYGVIRVDTEEKLSVLTVQDAGQVMPGGLVCVIRVEGTPYLCRTDEVGEICVSSSTTGISYYGLPGMTKNVFETIP--------------VTSSGAPISDRAFTRTSLLGFIGPDNLVFVVGKLDGLMVVSGRRHNADDVVATALAVEPMKFVYRG---------------------------------------------RIAVFSVSVLHDERIVVVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLG-GIHISESKQRFLEGALHPCNVLMCPHTCVTN-LPKPRQKQPGT-----------------EVGPASMIVGNLVAGKRIAQACGRDVTQLEDHD-----------QFLYLQDVLQWRAQATPDHPLFLLLNSKGTVVNTASCVQLHKR-----------AERVALALMERGRLNAGDHVALLYPPGIDLIATFYGCLYAGCVPVTVRPPHPQNLTTTLPTVKMIVEVSKSVCILTTQAIMKLLKSKEAAAAVDIKAWPLILDTDDLPRKRLPQIYKPPSPEMLAYLDFSVSTTGILAG------------------VKMSHAATSALCRSIKLQCELYPSRQIAICLDPYCGLGFALWCLCSVYSGHQSILVPPLELETNASLWLSAVSQYKVRVTFCSYSVMEMCTKGLGSQTEALRLRNVNLS----------------CVRTCMVVAEERPRITLTQSFSKIFKDLGLSTRAVSTTFGCRVNVAVCLQ----------GTAGPDPTTVYLDMRALRHDRVRLVER---GSPHSLPLMESGKILPGVKVIIANTETKGPLGDSHLGEVWVSSPHNATGYYTVYG------EEALHADHFNTKLSFGDT-QTVWARTGYLGFLRRTELTDAS----------------------------------------------------GERHDALYVVGALDETLELRGMRYHPIDIETSVIRSHKSIAECAVFTWTNLLVVVVELEGSEQEALD-LVALVTNVVLEEHYLIVGVVVVVDPGVIPINSR-------------------GEKQRMHLRDGFLADQLDPIYVAYNM-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E9PWR4-1", "uniprot_id": "E9PWR4_MOUSE", "id": "E9PWR4-1", "name": "", "aln": "MADRS-----------LEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPP-------------------------------------------------------------RVDQALPQERRAPVTPSSAS--------------------------------------RYHRRRSSGSRDERYRSDVHTEAVQAALAKHKER-KMAVPMPSKRRSLVVQTS--MDAYTPP------------DTSSGSEDEGSVQGDSQGTPTSSQGSIN-MEHWISQAIHGSTTSTTSSSSTQSGGS--------------------------GAAHRLADVMAQTHI---------------------------------------------ENHSAPPDVTTYTSEHS-IQVERPQGSTTSRTAPKYGNAELMETGDG-----------VPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLE-VQQPDPNQPKPEGAQMLATRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKVAYNILHKLGTK--QEPMVRPGDRVALVFPNNDPAAFMVAFYGCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVTVALTSDACHKGLPK-SPTGEIPQFKGWPKLLWFVTESKHLSKPPRDWFP-HIKDANNDTAYIEYKTCKDGSVLGVTVTRIALLTHCQALTQACGYTEAETIVNVLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQK--VCQYKAKVACVKSRDMHWALVAHRDQRDVNLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAIRRRGYGRLGNHS---GRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGIPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFP--------------MTSSGAPISEYPFIRTGLLGFVGPGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRG---------------------------------------------RIAVFSVTVLHDERIVIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLG-GIHLSETKQLFLEGSLHPCNVLMCPHTCVTN-LPKPRQKQP-------------------EIGPASVMVGNLVSGKRIAQASGRDLGQIEDNDQAR--------KFLFLSEVLQWRAQTTPDHLLYTLLNCRGTIANSLTCVQLHKR-----------AEKIAVMLMERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQIYKPSNPDTLAYLDFSVSTTGMLAG------------------VKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLS----------------RVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQ----------GTSGPDPTTVYVDMRALRHDRVRLVER---GSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSAHNASGYFTIYG------DESLQSDHFNSRLSFGDT-QTIWARTGYLGFLRRTELTDAN----------------------------------------------------GERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDGSEQEALD-LVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSR-------------------GEKQRMHLRDGFLADQLDPIYVAYNM-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZZB0-1", "uniprot_id": "D3ZZB0_RAT", "id": "D3ZZB0-1", "name": "", "aln": "MADRS-----------LEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPTANGAAVVRCRLQPGEGVPRRPFR-----SAHIGVCDIREAAARERAASAAGNRPLFYFRFGVDQALPQERRAPVTPSSAS--------------------------------------RYHRRRSSGSRDERYRSDVHTEAVQAALAKHKER-KMAVPMPSKRRSLVVQTS--MDAYTPP------------DTSSGSEDEGSVQGDSQGTPTSSQGSIN-MEHWISQAIHGSTTSTTSSSSTQSGGS--------------------------GAAHRLADVMAQTHI---------------------------------------------ENHSAPPDVTTYTSEHS-IQVERPQGSTTSRTAPKYGNAELMETGDG-----------VPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLE-VQQPDPNQPKPEGAQMLATRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKVAYNILHKLGTK--QEPMVRPGDRVALVFPNNDPAAFMVAFYGCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVTVALTSDACHKGLPK-SPTGEIPQFKGWPKLLWFVTESKHLSKPPRDWFP-HIKDANNDTAYIEYKTCKDGSVLGVTVTRIALLTHCQALTQACGYTEAETIVNVLDFKKDVGLWHGILTSVMNMMHVISIPYALMKVNPLSWIQK--VCQYKAKVACVKSRDMHWALVAHRDQRDVNLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAIRRP-TDDSNQPP---GRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGVPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFP--------------MTSSGAPISEYPFIRTGLLGFVGPGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRG---------------------------------------------RIAVFSVTVLHDERIVIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLG-GIHLSETKQLFLEGSLHPCNVLMCPHTCVTN-LPKPRQKQP-------------------EIGPASVMVGNLVSGKRIAQASGRDLGQIEDNDQARKVR----TEFLFLSEVLQWRAQTTPDHLLYTLLNCRGTIANSLTCVQLHKR-----------AEKIAVMLMERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQIYKPSNPDTLAYLDFSVSTTGMLAG------------------VKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLS----------------RVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQ----------GTSGPDPTTVYVDMRALRHDRVRLVER---GSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSAHNASGYFTIYG------DESLQSDHFNSRLSFGDT-QTIWARTGYLGFLRRTELTDAN----------------------------------------------------GERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDGSEQEALD-LVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSR-------------------GEKQRMHLRDGFLADQLDPIYVAYNM-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2E4-1", "uniprot_id": "DIP2C_HUMAN", "id": "Q9Y2E4-1", "name": "Disco-interacting protein 2 homolog C", "aln": "MADRS-----------LEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPP-------------------------------------------------------------RVDQALPQERRAPVTPSSAS--------------------------------------RYHRRRSSGSRDERYRSDVHTEAVQAALAKHKER-KMAVPMPSKRRSLVVQTS--MDAYTPP------------DTSSGSEDEGSVQGDSQGTPTSSQGSIN-MEHWISQAIHGSTTSTTSSSSTQSGGS--------------------------GAAHRLADVMAQTHI---------------------------------------------ENHSAPPDVTTYTSEHS-IQVERPQGSTGSRTAPKYGNAELMETGDG-----------VPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLE-VQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKVAYSILHKLGTK--QEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVTVALTSDACHKGLPK-SPTGEIPQFKGWPKLLWFVTESKHLSKPPRDWFP-HIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVNVLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQK--VCQYKAKVACVKSRDMHWALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAIRRP-TDDSNQPP---GRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGVPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFP--------------MTSSGAPISEYPFIRTGLLGFVGPGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRG---------------------------------------------RIAVFSVTVLHDERIVIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLG-GIHLSETKQLFLEGSLHPCNVLMCPHTCVTN-LPKPRQKQP-------------------EIGPASVMVGNLVSGKRIAQASGRDLGQIEDNDQAR--------KFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKR-----------AEKIAVMLMERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLDFSVSTTGMLAG------------------VKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLS----------------RVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQ----------GTSGPDPTTVYVDMRALRHDRVRLVER---GSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSAHNASGYFTIYG------DESLQSDHFNSRLSFGDT-QTIWARTGYLGFLRRTELTDAN----------------------------------------------------GERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDGSEQEALD-LVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSR-------------------GEKQRMHLRDGFLADQLDPIYVAYNM-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IRS1-1", "uniprot_id": "A0AC58IRS1_DANRE", "id": "A0AC58IRS1-1", "name": "", "aln": "MADR-------------DALPLPLEVRARLAELELELSEGDITQKGYEKKRSKLLGAYLPHPP-------------------------------------------------------------GLEASMAHDRRPPMAPSSAS--------------------------------------RYHRRRSSGTRDERYRSDVHTEAVQAALAKHKER-KMAVPMPSKRRSLVVQTS--MDAYTPPGLSPLSSLPPLTDTSSGSEEEG---GQGEGTPTSSQGSVS-MEHWISRAIHQGSTTSSSSSSTQSGGS--------------------------GAAGRLADVLAQTHMGKSGPIAHLSLKRKTMLGVAENGNSLRRSCEFGSDLLWPPPLESEENHSAPPDVTTYTSEHP-VQVERPQVSTVPRTTPKYGNAELMETGDG-----------VPVSSRVSAKIQQLVNTLKQPRRPPLREFFVDDFEELLE-VQQPDPNQPRPEGAQMVPIRGEPLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYVLTYGKLWSRSIKVAYNILHKLGTK--QEPMVRPGDRVALVFPNNDPAAFMVAFYGCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVTVALTSDACHKGLPK-GPTGEIPQFKGWPKLLWFVTESKHLSKPPRDWFP-HIKDANNDTAYIEYKTCKDGSVLGVTVTRIALLTHCQALTQSCGYTEAEIIVNVLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQK--VCQYKGKVACVKSRDMHWALVAHRDQRDINLSSLRMLVVADGSNPWSISSCDAFLNVFQSKGLRPEVICPCASSAEALTVAIRRP-TDDSNQPP---GRGVLSMQGLSYGVIRVDSEERLSVLTVQDVGTVMPGALMCVVKPEGVPQLCRTDEIGELCVCSIATGMSYYGLSGMTKNTFEVFP--------------MTISGAPISEYPFIRTGLLGFIGPGGLVFISGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRG---------------------------------------------RIAVFSVTVLHDERIVVVAEQRPDSTEEDSFQWMSRVLQAIDSIHNVGVFCLALVPANTLPKTPLG-GIHLSETKQLFLEGSLHPCNVLMCPHTCVTN-LPKPRQKQP-------------------EIGPASVMVGNLVSGKRIAQASGRDLGQIEDNDQAR--------KFLFLSEVLQWRAQTTPDHVLFTLLSSRGAVLSSLTCLQLHKR-----------AEKIATMLMERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACVMTTQIISKLLKSKEASAAVDVRTWPPVLDTDDLPKKKPPQLYKPSNPDTLAYLDFSVSTTGMLAG------------------VKMSHTATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPSELEVNPALWLLAVSQFRVRDTFCSYSVMELCTKGLGLQTESLKARGLDLS----------------RVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQPHRLGKLADQGTSGPDPTTVYVDMRALRHDRVRLVER---GSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHCAHNGSGYFTVYG------DEALQSDHFNSRLSFGDT-QTVWARTGYLGFLRRTELTDAS----------------------------------------------------GERHDALYVVGALDEAMELRGMRYHPIDIETSVIRTHKSIMECAVFPWTNLLVVVVELEGSEQEALD-LVPLVTNAVLEEHYLIVGVVVVVDIGVIPINSR-------------------GEKQRMHLRDGFLADQLDPIYVAYNM-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BIR2-1", "uniprot_id": "A0A8M2BIR2_DANRE", "id": "A0A8M2BIR2-1", "name": "", "aln": "MADR-------------DSLPLPLEVRARLAELELELSEGDITQKGYEKKRSKLLQAYLPHTP-------------------------------------------------------------GAERRIP--VTPSSSSSSSS--------------------------------------RYQRRRSTGSRDERYRSDVHSEAVQAALERHSER-KMAVLLPSKRRSLIGQTS--MDTYTPP------------DSSSGSDAEG---------SLGRAGGVS-VDSWISRALHG-SPSTSSSSSSHSNSS--------------------------ANAARLAETSMHTYAIGPMSHLSLKRRGLREMGVSAENGIVVRHSSDYHSDRPWSSLDSEDSLSAPPDITSYMPDSAPILVHRPQIAMITRPPPKYGNAELMETGDG-----------VPVSSRVSAKIQQLVNTLKRPKRRPLREFFVEDFEELLE-VQQPDPSLPRPEGAESIPIEGEELDRLKNCPASLEAALLRWGAIAPKAPCLTTTHSNAKQPYTLTYGKLWSRSLKLAYNLLHKLGSK--QEPIIHPGDRVALVYPNSDPAAFMVAFYGCLLAEVVPVPIEVPLTKKDAGSQQIGFLLGSCGVTVALASDACHKGLPK-SASGDVMQFKGWPKLLWVLTDSKHLSKPPREWFP-LIKDANNDTAYIEYKTCKDGSVMGITVTRMAMLSHCQTLTHTCGYSEAETVVNVLDFKKGIGLWHSVQTSVLNMLHVVSVPYALMKVNPLSWIQK--VCQYKAKVACVKSRDLHWALMAHKEQPDTNMSSLRMLLIADGSNPWSISSCDAFLNVFQNMGLRSEVICPCAGSPEALTVALRRP-QESSLKPA---GRGVLSMTNLSHGVIRVDTGEKLSVLTLQDVGTAMPGAVVCVVKVEGVPQLCKADEIGEICVSAVATGTSYYGLTGMSKNTFEVCP--------------VACDGGLVSDCVFVRSGLLGFVGPGRMIFISGTLEGLMQVGGRKHNADDIIATALAVEPMKFIYRG---------------------------------------------RTVVFSVTVLYDERIVLVAEQRPDSTEEESYQWMSRVLQAIDGIHQVGVYCLALVPANTLPKTPLG-GIHLSETKQLFLEGGLHPCSILMCPHSCITN-LPKPRQKQP-------------------EVGPASVMVGNLVAGKRMAQASGRDLSHMEDN-----------EQFLFLSEMLQWRAQTTPEHILYTLINSRGAVGSSLTCLQLHKR-----------AEKIATLLYERGQLRDGDHVALVYPPGLDLIAAFYGCLYAGCIPITVRPPHPQNISTTLPTVKMILEVSRSVCVMTSQMISKLLKSRDASVAVDFKLWPPILETDDLPKRRCPLLFKPCDPDSLAYLDFSVSTTGMLAG------------------VKMSHNATSALCRSVKLQCELYPSREVAVCLDPYCGLGFVLWCLCSVYAGQQSVLISPMDLEVNPALWLQAVSQFKVRDTFCSYSVMELCTRSLSSLTDTLKARGMDLT----------------RVRSCVVVAEERPRVALTQSFCKLFKDVGLHPRAVSTAFGCRVNLAICLQPHRLGKLAEQGTSGPDPTTVYVDMRALRHDRVRLVER---GSPHSLPLMESGKILPGVRIIIANPETKGPIGDSHLGEIWVHSPQNASGYFTVFG------EENVRSDHFGARLSFGDT-QTVWARTGYLGFLRRTDLTDAS----------------------------------------------------GERHDALYVVGALDEVMELRGMKYHPIDIETSIIRAHRNITECAVFTWTNLLVVVVELEGSEQEALD-LVPMVTNVVLEEHYLIVGVVVVVDTGVIPINSR-------------------GEKQRMHLRDGFLADQLDPIYVAYNM-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3UH60-1", "uniprot_id": "DIP2B_MOUSE", "id": "Q3UH60-1", "name": "Disco-interacting protein 2 homolog B", "aln": "MAERGLEP------SPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETDS--------------------------------------------------------IGQKE-RNQTPAPTAAQTSAP-------------------------------------SKYHRSRSGGARDERYRSDIHTEAVQAALAKHKEQ-KMALPMPTKRRSTFVQSP--ADACTPP------------DTSSASEDEGSLRR-QAALSAALQQSLQNAESWINRSIQGSSTSSSASSTLSHGEVKGTSG-------------------------SLADVFANTRIENVSAPP-------------------------------------DVTATTSS--SSSS--LRPANIDLPPSGIVKGMHKGSNRSSLMDTAD-----------GVPVNSRVSTKIQQLLNTLKRPKRPPLKEFFVDDSEEIVEGIPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGSTQAKCPCLTGLDVTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTK--NEPVLKPGDRVALVYPNNDPVMFMVAFYGCLLAEVIPVPIEVPLTRKDAGGQQIGFLLGSCGIALALTSEICLKGLPK-TQNGEIVQFKGWPRLKWVVTDSKYLSKPPKDWQP-HISPAGTEPAYIEYKTSKEGSVMGVTVSRLAMLSQCQALSQACNYSEGETVVNVLDFKKDAGLWHGMFANVMNKMHTISVPYSVMKTCPLSWVQR--VHAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSVSSCDAFLSLFQSHGLKPEAICPCATSAEAMTVAIRRP-GVPGAPLP---GRAILSMNGLSYGVIRVNTEDKNSALTVQDVGHVMPGGMMCIVKPDGLPQLCRTDEIGEICVSSRTGGMMYFGLAGVTKNTFEVIP--------------VTSSGSPVGDVPFIRSGLLGFVGPGSLVFVVGKMDGLLMVSGRRHNADDIVATGLAVESIKTVYRG---------------------------------------------RIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLG-GIHISQTKQLFLEGSLHPCNILMCPHTCVTN-LPKPRQKQP-------------------GVGPASVMVGNLVAGKRIAQAAGRDLGQIEENDLVRK--------HQFLAEILQWRAQATPDHVLFMLLNAKGTTVCTASCLQLHKR-----------AERIASVLGDKGHLNAGDNVVLLYPPGIELIAAFYGCLYAGCIPVTVRPPHAQNLTATLPTVRMVVDVSKAACVLTTQTLMRLLKSREAAAAVDVKTWPAIIDTDDLPRKRLPQLYKPPTPEMLAYLDFSVSTTGMLTG------------------VKMSHSAVNALCRAIKLQCELYSSRQIAICLDPYCGLGFALWCLCSVYSGHQSVLIPPMELENNLFLWLATVNQYKIRDTFCSYSVMELCTKGLGNQVEVLKTRGINLS----------------CIRTCVVVAEERPRVSLQQSFSKLFKDIGLSPRAVSTTFGSRVNVAICLQ----------GTSGPDPTTVYVDLKSLRHDRVRLVER---GAPQSLLLSESGKILPGVKVVIVNPETKGPVGDSHLGEIWVNSPHTASGYYTIYD------SETLQADHFNTRLSFGDAAQTLWARTGYLGFVRRTELTAAT----------------------------------------------------GERHDALYVVGALDETLELRGLRYHPIDIETSVSRVHRSIAECAVFTWTNLLVVVVELCGSEQEALD-LVPLVTNVVLEEHYLIVGVVVVVDPGVVPINSR-------------------GEKQRMHLRDSFLADQLDPIYVAYNM-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M0J6-1", "uniprot_id": "A0ABK0M0J6_RAT", "id": "A0ABK0M0J6-1", "name": "", "aln": "MAERGLEP------SPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETDS--------------------------------------------------------TGQKE-RNQTPAPTAAQTSAP-------------------------------------SKYHRSRSGGARDERYRSDIHTEAVQAALAKHKEQ-KMALPMPTKRRSTFVQSP--ADACTPP------------DTSSASEDEGSLRR-QAALSAALQQSLQNAESWINRSIQGSSTSSSASSTLSHGEVKGTSG-------------------------SLADVFANTRIENVSAPP-------------------------------------DVTATTSS--SSSL--LRPANIDLPPSGIVKGMHKGSNRSSLMDTAD-----------GVPVNSRVSTKIQQLLNTLKRPKRPPLKEFFVDDSEEIVE-VPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGTTQAKCPCLTGLDVTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTK--NEPVLKPGDRVALVYPNNDPVMFMVAFYGCLLAEVIPVPIEVPLTRKDAGGQQIGFLLGSCGIALALTSEICLKGLPK-TQNGEIVQFKGWPRLKWVVTDSKYLSKPPKDWQP-HISPAGTEPAYIEYKTSKEGSVMGVTVSRLAMLSHCQALSQACSYSEGETVVNVLDFKKDAGLWHGMFANVMNKMHTISVPYSVMKTCPLSWVQR--VHAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSVSSCDAFLSLFQSHGLKPEAICPCATSAEAMTIAIRRP-GVPGAPLP---GRAILSMNGLSYGVIRVNTEDKNSALTVQDVGHVMPGGMMCIVKPDGLPQLCKTDEIGEICVSSRTGGMMYFGLAGVTKNTFEVIP--------------VTSSGSPVGDVPFIRSGLLGFVGPGSLVFVVGKMDGLLMVSGRRHNADDIVATGLAVESIKTVYRGRHTGLLAVPQTCQARPHLRTFPLSAPSARNPLPPDLRVARVLTSFRIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQAIDTIHQVGVYCLALVPANTLPKTPLG-GIHISQTKQLFLEGSLHPCNILMCPHTCVTN-LPKPRQKQP-------------------GVGPASVMVGNLVAGKRIAQAAGRDLGQIEENDLVRK--------HQFLAEILQWRAQATPDHVLYVLLNAKGTTVCTASCLQLHKR-----------AERIASVLGDKGHLNAGDNVVLLYPPGIELIAAFYGCLYAGCIPVTVRPPHAQNLTATLPTVRMVVDVSKAACVLTTQTLMRLLKSREAAAAVDVKTWPAIIDTDDLPRKRLPQLYKPPTPEMLAYLDFSVSTTGMLTG------------------VKMSHSAVNALCRAIKLQCELYSSRQIAICLDPYCGLGFALWCLCSVYSGHQSVLIPPMELESNLSLWLATVNQYKIRDTFCSYSVMELCTKGLGSQVEALKTRGINLS----------------CIRTCVVVAEERPRVTLQQSFSKLFKDIGLSPRAVSTTFGSRVNVAICLQ----------GTSGPDPTTVYVDLKSLRHDRVRLVER---GAPQSLLLSESGKILPGVKVVIVNPETKGPVGDSHLGEIWVNSPHTASGYYTIYD------SETLQADHFNTRLSFGDAAQTLWARTGYLGFVRRTELTAAT----------------------------------------------------GERHDALYVVGALDETLELRGLRYHPIDIETSVSRVHRSIAECAVFTWTNLLVVVVELCGSEQEALD-LVPLVTNVVLEEHYLIVGVVVVVDPGVVPINSR-------------------GEKQRMHLRDSFLADQLDPIYVAYNM-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P265-1", "uniprot_id": "DIP2B_HUMAN", "id": "Q9P265-1", "name": "Disco-interacting protein 2 homolog B", "aln": "MAERGLEP------SPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETDS--------------------------------------------------------AVQKELRNQTPAPSAAQTSAP-------------------------------------SKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQ-KMALPMPTKRRSTFVQSP--ADACTPP------------DTSSASEDEGSLRR-QAALSAALQQSLQNAESWINRSIQGSSTSSSASSTLSHGEVKGTSG-------------------------SLADVFANTRIENFSAPP-------------------------------------DVTTTTSS--SSSSSSIRPANIDLPPSGIVKGMHKGSNRSSLMDTAD-----------GVPVSSRVSTKIQQLLNTLKRPKRPPLKEFFVDDSEEIVE-VPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGTTQAKCSCLTALDMTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTK--NEPVLKPGDRVALVYPNNDPVMFMVAFYGCLLAEVIPVPIEVPLTRKDAGGQQIGFLLGSCGIALALTSEVCLKGLPK-TQNGEIVQFKGWPRLKWVVTDSKYLSKPPKDWQP-HISPAGTEPAYIEYKTSKEGSVMGVTVSRLAMLSHCQALSQACNYSEGETIVNVLDFKKDAGLWHGMFANVMNKMHTISVPYSVMKTCPLSWVQR--VHAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSVSSCDAFLSLFQSHGLKPEAICPCATSAEAMTVAIRRP-GVPGAPLP---GRAILSMNGLSYGVIRVNTEDKNSALTVQDVGHVMPGGMMCIVKPDGPPQLCKTDEIGEICVSSRTGGMMYFGLAGVTKNTFEVIP--------------VNSAGSPVGDVPFIRSGLLGFVGPGSLVFVVGKMDGLLMVSGRRHNADDIVATGLAVESIKTVYRG---------------------------------------------RIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLG-GIHISQTKQLFLEGSLHPCNILMCPHTCVTN-LPKPRQKQP-------------------GVGPASVMVGNLVAGKRIAQAAGRDLGQIEENDLVRK--------HQFLAEILQWRAQATPDHVLFMLLNAKGTTVCTASCLQLHKR-----------AERIASVLGDKGHLNAGDNVVLLYPPGIELIAAFYGCLYAGCIPVTVRPPHAQNLTATLPTVRMIVDVSKAACILTSQTLMRLLRSREAAAAVDVKTWPTIIDTDDLPRKRLPQLYKPPTPEMLAYLDFSVSTTGMLTG------------------VKMSHSAVNALCRAIKLQCELYSSRQIAICLDPYCGLGFALWCLCSVYSGHQSVLIPPMELENNLFLWLSTVNQYKIRDTFCSYSVMELCTKGLGNQVEVLKTRGINLS----------------CVRTCVVVAEERPRVALQQSFSKLFKDIGLSPRAVSTTFGSRVNVAICLQ----------GTSGPDPTTVYVDLKSLRHDRVRLVER---GAPQSLLLSESGKILPGVKVVIVNPETKGPVGDSHLGEIWVNSPHTASGYYTIYD------SETLQADHFNTRLSFGDAAQTLWARTGYLGFVRRTELTAAT----------------------------------------------------GERHDALYVVGALDETLELRGLRYHPIDIETSVSRIHRSIAECAVFTWTNLLVVVVELCGSEQEALD-LVPLVTNVVLEEHYLIVGVVVVVDPGVIPINSR-------------------GEKQRMHLRDSFLADQLDPIYVAYNM-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NVJ5-1", "uniprot_id": "DI2BA_DANRE", "id": "Q6NVJ5-1", "name": "Disco-interacting protein 2 homolog B-A", "aln": "MADRGVD-----------LAALPKEVREQLAELELELSEGDITQKGYEKKRAKLLAPFVPQTQNVDV--------------------------------------------------------SILST--DSTSSPITIPIAAP-------------------------------------RQHRAHRSGGTRDDRYRSDIHTEAVQAALARHKEE-KMALPMPTKRRSAFVQSP--AENCTPP------------DTSSASEDEGSLRRRQAAISAMLAQNLQSPEYWINRSVQGSSTSSSASSTLSHGDGK-THN---------------HNNHSQGQTSALADVLAHT----RIDTN-------------------------------------SSSGSVPPDVTSTAPQDRNSRVDLPANIAVKGISRGQSRSSMMDTAG-----------GVPAHSRVSTKIQQLLNTLKRPKRPPLSEFFLDDSEEIVE-VPQPDPNTPRPEGRQIIPVKGEPLGVVSNWPPALQAALARWGATQAKSPALTALDITGKPLYTLTYGKLWSRSLKLAYTLLNKLGTK--NEPVLKPGDRVALVYPNSDPGMFWVAFYGCLLAEVIPVPIEVPLSRKDAGSQQIGFLLGSCGVGLALTSEVCLKGLPK-TPNGEIMQFKGWPRLKWVVTDTKYLTKPSKDWQP-HIPTANTDTAYIEYKASKEGTVMGVAVSKISMLTHCQALTQACNYCEGETLVNVLDFKKDSGLWHGVLTSVMNRIHTISVPYAVMKACPLSWVQR--VHVHKARVALVKCRDLHWAMMAHRDQKDTNLSSLRMLIVADGANPWSVSSCDAFLNVFQSHGLKPEMICPCASSPEAMTVAIRRP-GAPGTPLP---ARAILSMAGLSHGVIRVNTEDKNSALTVQDVGHVMPGALMCIVKPDGPPMLCKTDEIGEIVLNSRAGGTMYYGLPGVTKNTFEVIP--------------VNSGGTPIGDVPFTRTGLLGFVGPGSLVFVVGKIEGLLSVSGRRHNADDLVATALAVEPVKTVYRG---------------------------------------------RIAVFSVTVFYDERVVIVAEQRPDANEEDSFQWMSRVLQAIDSIHQVGLYCLALVPANTLPKTPLG-GIHVSETKHHFLEGSLHPCNILMCPHTCVTN-LPKPRQKQPV------------------GVGPASIMVGNLVAGKRIAQASGRDLGLIDDQEQSRK--------HQFLSEALQWRAQTDPDHVLYMLLNAKGVAVSTATCSQLHKR-----------AEKITAALLERGGINTGDNVVLLYPPGIDLIASFYGCLYAGCIPVTVRPPHPQNLSATLPTVRMIIDVSKAACILTTQTLMKTLRSKEAAASVNVKTWPNIIDTDDLPRKRPASIYKPPTAEMLAYLDFSVSTTGMLTG------------------VKMSHSAVNALCRSIKLQCELYSSRQIAICMDPYCGLGFVLWCLSSVYSGHQSILIPPMELETSLPLWLSTLSQYKIRDTFCSYSVMELCTKGLGTQTEALKARNVNLS----------------CVRSCVVIAEERPRLALTQSFSKLFKDLGLSPRAVSTAFGSRVNLAICLQ----------GTAGPDPSTVYVDMKSLRHDRVRLVER---GAPQSLPLMESGTMLPGVRVIIVNPETKGPLGDSHLGEIWVNSPHNASGYYTIYG------EESLQADHFNTRLSFGDT-ETLWARTGYLGFVKRTELLDAS----------------------------------------------------GDRHDALFVVGSLDETLELRGLRYHPIDIETSVSRAHRSIAESAVFTWTNLLVVVVELSGSEQEALD-LVPLVTNVVLKEHHLIVGVVVIVDPGVIPINSR-------------------GEKQRMHLRDSFLADQLDPIYVAYNM-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3BAI5-1", "uniprot_id": "A0A8M3BAI5_DANRE", "id": "A0A8M3BAI5-1", "name": "", "aln": "MAERGVD-----------VSALPQEVREQLAELDLELSEGDITQKGYEKKRAKVLAPYLAQAQDLAP--------------------------------------------------------PPAYD--EQSPGPSSASAPEPGPS------------------------NSSSSSSRHRRTRRPHRSGGTRDERYRSDIHTEAVQAALAKHKEE-KMALPMPTKRRSTYVQSP--IDNCTPP------------DSSSSSDDE--------AVSSESAGPQQSSDTWINSSLHGSSTSSSASSTLSHGESRPTQNPQPQSQQLPPPPAPAHPPHSHSQPSALAEAFAQTRIVRRIGRD-------------------------------------PVGGVGPPEVPSQA-QARGSRVDLPANAVVRGMSRGQSRSSMMETADVR-----RVGRGVPVSSRVSTKIQQLLNTLKRPKRPPLSEFFMDDQEEIVE-VPRADPNTPRPEGRQIIPVKGEPLGVVSNWPPALQAALARWGATQGKSPALTALDITGKPLYTLTFGKLWSRSVKLAYTLLNKLGTK--NEQILKPGDRVALVYPNSDPGMFWVAFYGCLLAEVIPVPIEVPLSRKDAGSSQVGFLLGSCGVGLALTSEICLKGLPK-TPTGEILQFKGWPRLKWVVTDSKYLTKPSKDWQP-HIPTANTDTAYIEYKASKEGTVMGVAVSKVAMLTHCQALSQACNYCEGETLVNVLDFKKDMGLWHGVLTSVMNRIHTISVPYAVMKACPLSWVQR--VHIHKARVALVKCRDLHWAMMAHRDQRDTSLASLRMLIVADGANPWSVSSCDAFLNVFQAHGLKPEVICPCATSPEAMTVAIRRP-GISGAPLP---ARAVLSMTGLSHGVIRVNTEDKNSALTVQDVGHVMPGALMCIVKPDGPPMLCKTDEIGEIVVNSRAGGNMYYGLSGVTKNTFEVIP--------------VNASGAPIGEIPFVRSGLLGFVGPGSLIFVVGKNEGLLMVSGRRHNADDLVATALAVEPVKTVYRG---------------------------------------------RIAVFSVTVFFDERIVIVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGLYCLALVPANTLPKTPLG-GIHISDTKQLFLEGALHPCNILMCPHTCVTN-MPKPRQKQPV------------------GVGPASIMVGNLVAGKRIAQAAGRDLGLIEDQDLVRKLCMWPTMMHQFLTEALQWRAQTDPDHTLYVLLNAKGVAVCTATCVQLHKR-----------AEKIAAALMERSGINIGENVVLLYPPGIDLIAAFYGCLYAGCIPVTVRPPHPQNLSATLPTVRMIIDVSKAACILTTQVLTKILRSKEAAATVNIKTWPIIIDTDDLPRKRPPTIYKPPNAEMIAYLDFSVSTTGMLTG------------------VKISHAAVSALCRSIKLQCELYSSRQIAICLDPYCGLGFVLWCLASVYSGHQSILIPPMELETSLTLWLGTLSQYRIRDTFCSYSVMELCTKGLGGQTELLKARGVNLS----------------CVRSCVVIAEERPRLALTHSFSKLFKDIGLSMRAVSTAFGSRVNLAICLQ----------GTTGPDPSTVYVDMKSLRHDRVRLVER---GAPQSLPLMESGTILPGVRVVIVNPETRGPLGDSHLGEIWVNSPHNATGYYTIYG------EENLQADHFNTKLSFGDP-QTLWARTGYLGFVKRTELTDAS----------------------------------------------------GDRHDALFVVGYLDETLELRGLRYHPIDIETSVSRAHRSIGESAVFTWTNLLVVVAELCGSEQDALD-LVPLVTNVVLEEHHLIVGVVVIVDPGVIPINSR-------------------GEKQRMHLRDSFLADQLDPIYVAYNM-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0S9-1", "uniprot_id": "DIP2_DROME", "id": "Q9W0S9-1", "name": "Disco-interacting protein 2", "aln": "---------------MEHTASLPGYVREKLAELDLELSEGDITQKGYEKKRAKLLQPFLKKPEGDKVKSTPPPPYYNVKNANNSTNHGNINNDGVIVSSEGYSYVTEVPSLSSSQQRHSKKIDFHQQAAMSLSSAPQSGNAGAPGYENMRPQGGAVGDPGYQNTREPSAFQNQQSTNNSQHRQRRTQRKVTHNEKRYHSEVRQEAVQQALAALKGRPKPSLPMPSKRTSVLNRSPGCNDELDSS-----------TDDESIPEETISPDKEYNYPRDHISNSILPPEPIIKPPIRESSMGSQQHARTDVKQNQITNQKYTAPN----------SAPERRPPQNLPPLPTSEPLSSDYPP---------------------------------------IAYKRENDFSDKAFKQK--QYNAPDITQFNNAHRAADRVTRYVNVSQNELN----ETDANGKWKVSAKIQQLLNTLKRPKRRPLPEFYEDNDIELEIAANTKDPNAPKPEGSTMTPVQGEQLSIPAGLPRTLECALQRYGTNSFKSPMATVLDPNGKVTTTLTYGKLLSRAQKIAHALSTKIFSKGPEQVTLKPGDRVALVYPNNDPLSFITAWYGCMFRGLVPLPIELPLSSSDTPPQQVGFLLSSCGITVALTSEACLKGLPKSTTTGEIAKLKGWPRLQWFVTE--HLPKPPKEFNVGNLRADDSAAAYIEYTTDKEGSVMGVTVTRAAMINHCRALTMACHYTEGETIVCVLDFKREVGLWHSVLTSVLNGMHVIFIPYALMKLRPSSWMQL--ITKHRASCCLVKSRDLHWGLLATKDHKDISLSSLRMLLVADGANPWSLSSCDQFLSVFQAKGLRSDAICPCASSSEVFTVSLRRPGRGSCGFSPSATGRGVLSMAALSHGVVRVDSEDSLTSLTLQDCGQVMPAAQMVVVRSEGPPVLCKTDQVGEICVTSGSTSASYFGLDGMTNSTFKVQPLLEELEQPKDGNGTVNIISKPIGEDFYVRSGLLGFLGPGGLVFVCGSRDGLMTVTGRKHNADDIIATVLAVEPMRFIYRG---------------------------------------------RIAVFSIKVLRDERVCVIAEQRPDCSEEESFQWMSRVLQAVDSIHQVGIYCLALVPPNHLPKTPLG-GIHLCEARRRFLEGSLHPANVLMCPHTCVTN-LPKPRELHQGVQTAAKLSSSSGCGITDTGVGPASVMVGNLVQGNRLAEAHGRDVGLAEDCERKP----------QLITGVLRWRANTSPDHIIFTLLNSKGAIAKTLTCSELHKR-----------AEKIAALLQERGRIEPGDHVALIFPPGLDLLCAFYGCLYLGAIPITIRPPHPQNLNTTLPTVRMIVDVSKSGIVLSIQPIIKLLKSREAATSIDPKTWPPILDIDDNPKRKYAGIAT-VSFDSSAYLDFSVSTCGRLSG------------------VNITHRSLSSLCASLKLACELYPSRHVALCLDPYCGLGFVMWTLIGVYSGHHSILIAPYEVEANPSLWLSTLSQHRVRDTFCSYGVIELCTKALSNSIPSLKQRNIDLR----------------CVRTCVVVAEERPRVQLTQQFCKLFQALGLNTRCVSTSFGCRVNPAICVQ----------GASSAESAQVYVDMRALRNNRVALVER---GAPNSLCVIESGKLLPGVKVIIANPETKGHCGDSHLGEIWVQAPHNANGYFTIYG------DETDYNDHFNAKLVTGAT-SELYARTGYLGFLRRTECSQSASLLDETTPSVASRDSDTESLNSISQLQLNFSNVSLGGNSEHSLVGGASNANDQELHDAVYVVGAVDEVISLRGMNYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVVELDGNESEALD-LVPLVTNTVLEDHQLIVGVVVVVDPGVVPINSR-------------------GEKQRMHLRDGFLADQLDPIYVAYNM-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12275-1", "uniprot_id": "CRM2_YEAST", "id": "Q12275-1", "name": "Homeostatic regulator of DAG", "aln": "-------------MDFSIPPTLPLDLQSRLNELIQDYKDENLTRKGYETKRKQLLDKFEISQMR--------------------------------------------------------------------PYTPLRSPNSRK--------------------------------------SKHLHRRNTSLASSITSLPNSIDRRHSIYRVTTINSTSANNTPRRRSKRYTAS--LQSSLPG---------------SSDENGSVKDAVYNPMIPLLPRHTGAENTSSGDSAMTDSLPLILRGRFEHYDG----------------------------QTAMISINSKGKE-----------------------------------------------TFITWDKLYLKAERVAHELNKSHLYKMDKILLWYNKNDVIEFTIA------------LLGCFISGMAAVPVSFETYSLREILEIIKVTNSKFVLISNACHRQLDNLYSSSNHSKVKLVKNDVFQQIKFVKTDDLGTYTKAKKTSPTFDIPNISYIEFTRTPLGRLSG--VVMKHNILINQFET-----MTKILNSRSMPHWKQKSQSIRKPFHKKIMATNSRFVILNSLDPTRSTGLIMGVLFNLFTGNLMISIDSSILQRPG-GYENIIDKFR----ADILLNDQLQLKQVVINYLE-NPESAFSKKHKIDFSCIKSCLTSCTTIDTDVSEMVVHKWLKNLGCIDAPFCYSPMLTLLDFGGIFISIRDQLGNLENFPIHNSKLRLQNELFINREKLKLNEVECSITAMINSSSSFKDYLKLETFGFPIPDITLCVVNPDTNTLVQDLTVGEIWISSNHITDEFYQMDKVNEFVFKAKLNYSEMFSWAKYEMPTNEKSQAVTEQLDTILNICPANTYFMRTKLMGFVHNGKIYVLSLIEDMFLQNRLIRLPNWAHTSNLLYAKKGNQSAQPKGNTGAES--------TKAIDISSLSGETSSGYKRVVESHYLQQITETVVRTVNTVFEVAAFELQHHKEEHFLVMVVESSLAKTEEES--------------------------------------------------KNGETTDTTLMKFAETQRNKLETKMNDLTDQIFRILWIFHKIQPMCILVVPRDTLPRRYCSLELANSTVEKKFLNNDLSAQFVKFQFDNVILDFLPHSAYYNESILSEHLSKLRKMALQEEYAMIEPAYRNGGPVKPKLALQCSGVDYRDESVDTRSHTKLT----DFKSILEILEWRISNYGNETAFSDGTNTNLVNSSASNDNNVHKKVSWASFGKIVAGFLKKIVGSKIPLKHGDPIIIMCENSVEYVAMIMACLYCNLLVIPLPSVKESVIEEDLKGLVNIIQSYKVKRVFVDAKLHSLLNDNNVVNKCFKKYKSLIPKITVFSKVKTKNALTVSMFKNVLKQKFGAKPGTRIGMTPCVVWVNTEYDVTSNIHVTMTHSSLLNASKIVKETLQLRNNSPLFSICSHTSGLGFMFSCLLGIYTGASTCLFSLTDVLTDPKEFLIGLQNLNVKDLYLKLETLYALLDRASSLIEGFKNKKENINSAKNNTSGSLREDVFKGVRNIMIPFPNRPRIYTIENILKRYSTISLSCTQISYVYQHHFNPLISLR----------SYLDIPPVDLYLDPFSLREGIIREVNPNDVSAGNYIKIQDSGVVPVCTDVSVVNPETLLPCVDGEFGEIWCCSEANAFDYFVCNSSKNKLYKDPFITEQFKSKMKSEVNNTLSYLRTGDLGFIKNVSCTNSQG--------------------------------------------------EVVNLNLLFVLGSIHESIEILGLTHFVSDLERTVKDVHSDIGSCLIAKAGGLLVCLIRCKERHNPILGNLTTLIVSELLNKHGVILDLCTFVRTKGISPKNSSMIMEVWAKNRASIMQAWFDQKIQIEAQFGINYGENISIYLLSDYEKDNI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .** : * ** : .: ::*:****.** ::: : . : :: . . . ..:* * :. : . * : : : . : . . :* :. . . * * : : : .. * : ... . . *:* : . : : . : :: . :... : .:: :: . * .* . : :*.*:. : :: : . * . : :: .: : : : :: . *::. *. . :: : :. : * . . :. :. . : : :: ::: : . . . : .: :. : : . ..:. :: . . .:: . : : * . : . . . ..: : : * . . :. : .: : : . . .:. . . . . . :: .. : ::*: :..:. : . : .. . * : .** : : * . : .:::: : :*:: *: :** : **: . : . .: **:. * . : : .. : : :*:. : : .: *. * : :. * : . : *.** :. : . . : : : :: * : : .: : *: : :: .:: :. : .*** . : :.: . : . : * : ::: : :: : *...:. : . : . .: : . .*.... : *.::* : . :* :* . : . .**** : * .:*:* : *.. :: . :* :.: . : : . .: . :: : :: :*. :: :***: ..: * :. :.* :* : :.* :.:: . . . :*:* :**.. : *: .: : : : :** : . : :.:.** *..:**:* . .. .*:. . .: ::* ::: : *** ***::... : : ::*:* :.* :.: *: :. *:* :: * .: .. : .*** : . .. *. *..::.. :*:.* :::.: ..* :. :. .:* ::. : .: .: .**: : ", "identical_positions": 120, "similar_positions": 469, "identity": "5.98%" }, { "cls_id": "homologset.agr.SGD:S000005620", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62330-1", "uniprot_id": "ARF6_HUMAN", "id": "P62330-1", "name": "ADP-ribosylation factor 6", "aln": "MG----KVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTR-IRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62332-1", "uniprot_id": "ARF6_RAT", "id": "P62332-1", "name": "ADP-ribosylation factor 6", "aln": "MG----KVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTR-IRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62331-1", "uniprot_id": "ARF6_MOUSE", "id": "P62331-1", "name": "ADP-ribosylation factor 6", "aln": "MG----KVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTR-IRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40946-1", "uniprot_id": "ARF6_DROME", "id": "P40946-1", "name": "ADP-ribosylation factor 6", "aln": "MG----KLLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARTELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTR-IRDRNWYVQPSCATSGDGLSEGLIWLTSNHKL---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40994-1", "uniprot_id": "ARF3_YEAST", "id": "P40994-1", "name": "ADP-ribosylation factor 3", "aln": "MGNSISKVLGKLFGSKEMKILMLGLDKAGKTTILYKLKLNKIKTSTPTVGFNVETVTYKNVKFNMWDVGGQQRLRPLWRHYFPATTALIFVIDSSARNRMEEAKEELYSIIGEKEMENVVLLVWANKQDLKDAMKPQEVSDFLELEKNLKNQPWCVIGSNALSGQGLVEGLSWISNNTNVPKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *:*.*:**.***:******* ************.: *: ******************:******:::*******:..* .****:*.: *:*::**: **: **.::**.:.::*::****** *****:*:.: * * : :::: * * * * **:** *** *::.* : ", "identical_positions": 105, "similar_positions": 48, "identity": "57.38%" }, { "cls_id": "homologset.agr.SGD:S000005621", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7L6-1", "uniprot_id": "D4A7L6_RAT", "id": "D4A7L6-1", "name": "Ribose-5-phosphate isomerase", "aln": "MQRPGPFSTLYGRVLAPLPGRAGGAASGGGGNNWGLSGSHVQLPGRTQSETRGDKGGSSAGG-------PAPSTMSKAEEAKKLASHTAVENHVKNN--QVLGIGSGSTIVHAVQRIAERVKQEN-----LDLICIPTSFQARQLILQYGLTLSDLDQHPEIDLAIDGADEVDAELNLIKGGGGCLTQEKIVAGYASRFIVIADFRKDS-KNLGDRWHKGIPIEVIPMAYVPVS-RAVTQKFGGEVELR-MAVNKAGPVVTDNGNFILDWKF--DRVHKWGEVNTAIKMTPGVVDTGLFINMAERVYFGMQDGSVNVREKPF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47968-1", "uniprot_id": "RPIA_MOUSE", "id": "P47968-1", "name": "Ribose-5-phosphate isomerase", "aln": "MQRPGPFSTLYGRVLAPLPGRAGGAASGGGGNNWGLSGSHVQLPGRAHSETRGDKGGSSAGG-------PAPSTMSKAEEAKKLASHTAVENHVKNN--QVLGIGSGSTIVHAVQRIAERVKQEN-----LDLICIPTSFQARQLILQYGLTLSDLDQHPEIDLAIDGADEVDAELNLIKGGGGCLTQEKIVAGYASRFIVIADFRKDS-KNLGDRWHKGIPIEVIPMAYVPVS-RAVAQKFGGEVELR-MAVNKAGPVVTDNGNFILDWKF--DRVHKWSEVNTAIKMTPGVVDTGLFINMAERVYFGMQDGSVNVREKPF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49247-1", "uniprot_id": "RPIA_HUMAN", "id": "P49247-1", "name": "Ribose-5-phosphate isomerase", "aln": "MQRPGPFSTLYGRVLAPLPGRAGGAASGGGGNSWDLPGSHVRLPGRAQSGTRGGAGNTSTSCGDSNSICPAPSTMSKAEEAKKLAGRAAVENHVRNN--QVLGIGSGSTIVHAVQRIAERVKQEN-----LNLVCIPTSFQARQLILQYGLTLSDLDRHPEIDLAIDGADEVDADLNLIKGGGGCLTQEKIVAGYASRFIVIADFRKDS-KNLGDQWHKGIPIEVIPMAYVPVS-RAVSQKFGGVVELR-MAVNKAGPVVTDNGNFILDWKF--DRVHKWSEVNTAIKMIPGVVDTGLFINMAERVYFGMQDGSVNMREKPFC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MLS2-1", "uniprot_id": "Q8MLS2_DROME", "id": "Q8MLS2-1", "name": "ribose-5-phosphate isomerase", "aln": "------------------------------------------------------------------------MDDIALDAAKKTAARTAVDQWVTEDT-KILGIGSGSTVVYAVQRIAERVWKEGE---LTDLICVPSSYQARHLILDYNLNLGDLDRNPNIDVAIDGADEVDRHMVLIKGGGGCLLQEKVVASCAKHFIVVADYTKNS-IRLGEQWCRGVPIEVAPMAYVPIK-LHIEALFGGEASLR-MAKVKAGPIVTDNGNFLLDWKFIANREYDWDEVNRAITLIPGVLETGLFVNMAHKCYYGMANGSVKVQNK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12189-1", "uniprot_id": "RPIA_YEAST", "id": "Q12189-1", "name": "Ribose-5-phosphate isomerase", "aln": "--------------------------------------MAAGVPKIDALESLG----------------------NPLEDAKRAAAYRAVDENLKFDDHKIIGIGSGSTVVYVAERIGQYLHDPKFYEVASKFICIPTGFQSRNLILDNKLQLGSIEQYPRIDIAFDGADEVDENLQLIKGGGACLFQEKLVSTSAKTFIVVADSRKKSPKHLGKNWRQGVPIEIVPSSYVRVKNDLLEQLHAEKVDIRQGGSAKAGPVVTDNNNFIIDADF--GEISDPRKLHREIKLLVGVVETGLFIDNASKAYFGNSDGSVEVTEK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **: *. **:: : : :::*******:*:..:**.: : . .::*:*:.:*:*:***: * *..::: *.**:*:******* .: ******.** ***:*: *. ***:** *.* .**..* :*:***: * :** :. : .. ..:* . ****:****.**::* .* .. . ::: *.: **::****:: * : *:* :***:: :* ", "identical_positions": 92, "similar_positions": 84, "identity": "28.48%" }, { "cls_id": "homologset.agr.SGD:S000005622", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62081-1", "uniprot_id": "RS7_HUMAN", "id": "P62081-1", "name": "Small ribosomal subunit protein eS7", "aln": "MFSSSAKIVKPNGEKPDEFESGISQALLELEMNS-DLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDVNFEFPEFQL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62082-1", "uniprot_id": "RS7_MOUSE", "id": "P62082-1", "name": "Small ribosomal subunit protein eS7", "aln": "MFSSSAKIVKPNGEKPDEFESGISQALLELEMNS-DLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDVNFEFPEFQL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62083-1", "uniprot_id": "RS7_RAT", "id": "P62083-1", "name": "Small ribosomal subunit protein eS7", "aln": "MFSSSAKIVKPNGEKPDEFESGISQALLELEMNS-DLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDVNFEFPEFQL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62084-1", "uniprot_id": "RS7_DANRE", "id": "P62084-1", "name": "Small ribosomal subunit protein eS7", "aln": "MFSTSAKIVKPNGEKPDEFESGISQALLELEMNS-DLKAQLRELHITAAKEIEVGGSRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTNVHDAILEDLVFPSEIVGKRIRVKLDSSRLIKVHLDKAQQNNVEHKVETFAGVYKKLTGKDVIFEFPEFQL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VA91-1", "uniprot_id": "RS7_DROME", "id": "Q9VA91-1", "name": "Small ribosomal subunit protein eS7", "aln": "-MAIGSKIIKPGGSDPDDFEKSIAQALVELEANS-DLKPYLRDLHITRAREIEFG-SKKAVIIYVPIPQQKVFQKIQIILVRELEKKFSGKHVVVIAERKILPKPTRKARNPLKQKRPRSRTLTAVYDAILEDLVFPAEIVGKRIRVKLDGSQLVKVHLDKNQQTTIEHKVDTFTSVYKKLTGRDVTFEFPDNYLNV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P26786-1", "uniprot_id": "RS7A_YEAST", "id": "P26786-1", "name": "Small ribosomal subunit protein eS7A", "aln": "MSAPQAKILS---QAPTELELQVAQAFVELENSSPELKAELRPLQFKSIREIDVAGGKKALAIFVPVPSLAGFHKVQTKLTRELEKKFQDRHVIFLAERRILPKPSRTSR--QVQKRPRSRTLTAVHDKILEDLVFPTEIVGKRVRYLVGGNKIQKVLLDSKDVQQIDYKLESFQAVYNKLTGKQIVFEIPSETH--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :**:. . * ::* ::**::*** .* :**. ** *::. :**:.. .:**: *:**:*. *:*:* *.*******..:**:.:*:*:*****:*.:* ********** *:* ********:******:* :...:: ** **. : :::*:::* .**:****::: **:*. ", "identical_positions": 87, "similar_positions": 65, "identity": "44.16%" }, { "cls_id": "homologset.agr.SGD:S000005624", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P20676-1", "uniprot_id": "NUP1_YEAST", "id": "P20676-1", "name": "Nucleoporin NUP1", "aln": "----------------------MSSNTSSVMSSPRVEKRSFSS-----------TLKSFFTNPNKKRPSSKKVFSSNLSYAN-------HLEESDVEDTLHVNKRKRVSGTSQHSDSLTQN-------------NNNAPIIIYGTENTERPPLLPILPIQR-----------LRLLREKQRVRNMRELGLIQSTEFPSITSSVILGSQSKSDEGGSYLCTS----STPSPIKNGSCTRQLAGKSGEDTNVGLPILKS----LKNRSNRKRFHSQSKGTVWSANFEYDLSEYDAIQKKDNKDKE------------------GNAGGDQKTSENRNNIKSSISNGNLATGPNLTSEIEDLRADINSNRLSNPQKNLLLKGPASTVAKTAPIQESFVPNSERSG--TPTLKKNIEPKKDKESIVLPTVGFDFIKDNETPSKKTSPKATSSAGAVFKSSVEMGKTDKSTKTAEAPTLSFN------FSQKANKTKAVDNTVPSTTLFNFGGKSDTVTSASQPFKFGKTSEKSENHTESDAPPKSTAPIFSFGKQEENGDEGDDENEPKRKRRLPVSEDTNTKPLFDFGKTGDQKETKKGESEKDASGKPSFVFGASDKQAEGTPLFTFGKKADVTSNIDSSAQFTFGKAATAKETHT-------------KPSETPATIVKKPTFTFG------QSTSENKISEGSAKPTFSFSKSEEERKSSPISNEAAKPSFSFPGKPVDVQAPTDDKTLKPTFSFTEPAQKDSSVVSEPK-----------------------------------------KPSFTFASSKTSQPKPLFS--------FGKSD----------AAKEPPGSNTSFSFTKPPANETDKRPTPPS----------FTFGGSTTNNTTTTSTKPSFSFGAPESMKSTASTAAANTEKLSNGFSFTKFN-------------------------------------------------------HNKEKSNSPTSFFDGSASSTPIPVLGKPTDATG-----------NTTSKSAFSFGTANTNGTNASANSTSFSFNAPATGNGTTTTSNTS------GTNIAGTFNVGKPDQSIASGNTNGAGSAFGFSS-----SGTAATGAASNQSSFNFGNNGAGGLNPFTS-------------------------ATSSTNANAGLFNKPPSTNAQ---------NVNVP-SAFNFTGNNSTPGGGSVFNMNG--NTNANTVFAGS-------NNQPHQSQTPSFNTN---------------------------------SSFTPSTVPNIN-FSG-LNGGITNTATNALRPSDIFGANAASGSN----------------SNVTNPSS----------IFGGAGGVPTT-SFGQPQSAP--------------NQMGMGTNNGMSMGGGVMANRKIARMRHSKR------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VGL0-1", "uniprot_id": "Q9VGL0_DROME", "id": "Q9VGL0-1", "name": "", "aln": "----------------MERRRFNMSSMSPMADSTRIDASLLNNRPAASNFLRGLSPKGSNTSLNGTRTPERSLMNRSATSSSTITRQKLNLSQVDPRTFADVHSSGLSSRIVALSERSGLQ-------------RSMSASNLYNPLTQPRRAPASPLPYKS-----------RAPTLSITQIAPPERSFYSGNTLSSLLRSNSLVGLVPKTTEQEQLSRENRPILHPPHPQHESEPTRSVLEELKEISRKRINTEDT----QQAQDYTKRSCQQNVDFVDFVAHHRQQQKLRNLQQQQNQSFKRQRELTVSVPLRHHSTSLSAASPALQHMNSNGTISPTQSPEQVAKRPNCSYSNDITSSLSSSCRHSNKRKLLDMRERFQHSKNDTLASGGSSPENSPEN--VAKIQRKVDAEAVSKAMSMPVVTVAAVPASRAISAPAIQKAVPQVTEKPKLTLFNARQSQTIAEQPRPDLSSPEVDAGEYAGIQFVKPKQQNSMLAAKNPSVERTHKTKLAIMLSGLKGELYLGEPDELDAPAPKSAPAPVTLPTPVKPIIIAPVTTSTTTVTSTATISTSAPSKPIILSNQVIKPADVPNTNSTGSVP-KLVLGQPAPPAKTEQTPPKPIDKVPAAQADIPPKFELSTKPVTPATSSQP-------------LISFGTPKSTAAPSFSFGSATNTTSSTIANITNTTTSKPIFSFGQTPAN--GPTVGGLSGFKTEAPATTSVSTTNPGTQVTSTTTFGVTPPKTTTTVAPTTTVSLN------------------------------------FGQPMPSFGAADTG-VKPMFS--------FGKSNNLSSGTPTTNGSDAAAAKPAVFSFGGSTTQPAAAAPTPVFGSLSKPLGEGFASPGANKSETTKPSIFGNLDNGLGNAMKSSTNVAATTAAELPKPFGFAATT-------------------------------------------------------TAAGGGSTATNLFSFGGTATSKAAEPAPASQKNLFGL-------NATTTTPFAFGGAAAGAADKSENKDNKPIAFAFGAGNNSAVANPSGVFSFGGTDKSAPPAFGSGTTSVTSATATPTNNTFGFST-----TQKPATPMFGSGSTQQSSTPAVAATKPFTLGGGAPTTPSASPASGGFSFSAVATKNTTAPTAGTNLFGSPASASKP---------SFNFGGNTATQAAAAGSPAGGFSFATTTKKEDSASTNMFGS-------PNTGVVKPNFSFSSNNPTPAP-TFGGFGAPAAAAPTATSTNQSKPFAFGASTPAAAPQPP-LGGNLFANAVSATQNQTKPSGVFSFGAAKSTAGTTAGNAPFSFGGASAGGIASPPSNQGLNTAKPFSFGGAGGTPAPNVFGSPAPAPPASNPTGG-----FNFGGVSPAQQANAGNMFAPTPESRPIRKATRRLQK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E9Q3G8-1", "uniprot_id": "NU153_MOUSE", "id": "E9Q3G8-1", "name": "Nuclear pore complex protein Nup153", "aln": "MASEAGGIGGGGGGGKIRTRRCHQGPVKPYQQGRPQHQGILSRVTESVKNIVPGWLQRYFNKSENACSCSPDADEVPPWPENREDEHAIYADENTNTDDGRITPDPAGSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSVLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRASEKDIAVSKNTSLPPLWSPEAERSHSLSQHTAISSKKPAFNLSAFGTLSTSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQNKVRSTPYQAPVRRQMKAKQLNAQSYGVTSSTARRILQSLEKMSSPLADAKRIPSAVSSPLNSPLDRSGIDNTVFQAKKEKVDSQYPPVQRLMTPKPVSIATNRTVYFKPSLTPSGDLRKTNQRIDKKNSTVDEKSISRQNREQESGFSYPNFSIPAANGLSSGVGGGGGKMRRERTHFVAPKPPENEEVEAPLLPQISLPISSSSLPTFSFSSPVTSASPSPVSSSQPLPNKVQMTSLGSTGSPVFTFSSPIVKSTQAAVLPPASIGFTFSVPLAKTEFSGSNSSSETVLSSSAQDITAVNSSSYKKRSAPCEDPFTPAKILREGSVLDILKTPGFASPKVDSPALQPTTTSSIVYTRPAISTFSSSGIEYGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLPLKETAKQTGTGTPSKSDKPASTSGTGFGDKFKPAIGTWDCDTCLVQNKPEAVKCVACETPKPGTGVKRALTLTVASESPVTASSSTTVTTGTLGFGDKFKRPVGSWECPVCCVCNKAEDNRCVSCTSEKPGLVSASSSSPAPVSLSSGGCLGLDKFKKPEGSWDCEVCLVQNKADSAKCIACESAKPGTKSEFKGFGTSSSLNPAPSAFKFGIPSSSSGLSQTLTSTGNFKFGDQGGFKLGTSSDSGSTNTMNTNFKFSKPTGDFKFGVLSDSKPEEVKNDNKNDNFQFGSSSGLTNPASSAPFQFGVSTLGQQEKKEELPKSSPAGFSFGAGVNNPPNAAIDTTATSENKSGFNFGTLDTKSVSVTPFTYKTTEAKKEDAPATKGGFTFGKVGSSSLPSSSMFVLGRTEEKQQEPVTSTSLVFGKKADSEEPKCQPVFSFGNSEQTKDESSKPTFSFSVAKPSGKESEQLAKATFAFGNQTNTTTDQGAAKPVFSFLNSSSSSSSAPATSSSGGIFGSSTSSSNPPVAAFVFGQASNPVSSSAFGNAAESSTSQSLLFPQESEPATTSSTAPAASPFVFGTGASSNSVSSGFTFGATTTSSSSGSSFVFGTGHSAPSASPAFGANQTPTFGQSQGASQPNPPSFGSISSSTALFSAGSQPVPPPIFGTVSSSSQPPVFGQQPSQSAFG---SGTANASSVFQFGSSTTNFNFTNNNPSGVFTFGASPSTPAASAQPSGSGVFSFSQSPASFTVGSNGKNMFSSSGTSVSGRKIKTAVRRKK", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. .. . :. : .. : . . . . . .: : * * . : .. : . . :* . .: . : .. : .. . . . * : . : . : : . * . .. . :: : :. *. . :... . : . : . . * . : . . .. . ..:..: .. : : . * . . : .: * :* : .. :. . . . . :: . :. . . . . . : ... .. : . . : . :* . . . :: . . :. : ..:.: : . . ::.. .*... .. . . . . . . * * . :: .* . . . : . :* .::.: .: * * *.: . ... . . :: . * .:... : . : .:. * .:* :. : .: : . * *: . .... *. . . .. .. .: . ::.: :.*:: : : : . .. . .: .. :: : . . : :. . :** * : ..: .: : . . . .* :.:..:. .:*....*:. * .: . .:.. . * .:.* .* . . :*.:. . :: *: :.. . :: . *. :*. ::.. .. :...* .. . ** . .:* . . . . . .. *: . ", "identical_positions": 45, "similar_positions": 334, "identity": "3.07%" }, { "cls_id": "homologset.agr.SGD:S000005626", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97521-1", "uniprot_id": "MCAT_RAT", "id": "P97521-1", "name": "Mitochondrial carnitine/acylcarnitine carrier protein", "aln": "-------------MAE---EPKPISPLKN---------LLAGGFGGVCLVFVGHPLDTVKVRLQTQPP--SLPGQPPMYSGTIDCFRKTLFREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKRLQ----QKSPEDELTYPQLFTAGMLSGVFTTGIMTPGERIKCLLQIQASS-GKNKYSGTLDCAKKLYQEFGIRGFYKGTALTLMRDVPASGMYFMTYEWLKNLFTP-----QGKSVHDLSVPRVLVAGGFRGIFNWVVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIREEGVTSLYKGFNAVMIRAFPANAACFLG----------------------------FEIPMKILN----------------------WIAPNL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2Z6-1", "uniprot_id": "MCAT_MOUSE", "id": "Q9Z2Z6-1", "name": "Mitochondrial carnitine/acylcarnitine carrier protein", "aln": "-------------MAD---EPKPISPFKN---------LLAGGFGGMCLVFVGHPLDTVKVRLQTQPP--SLSGQPPMYSGTLDCFRKTLMREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQ----QKSPEDELSYPQLFTAGMLSGVFTTGIMTPGERIKCLLQIQASS-GENKYSGTLDCAKKLYQEFGIRGFYKGTVLTLMRDVPASGMYFMTYEWLKNLFTP-----EGKSVSDLSVPRILVAGGFAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIREEGVTSLYKGFNAVMIRAFPANAACFLG----------------------------FEIAMKFLN----------------------WIAPNL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43772-1", "uniprot_id": "MCAT_HUMAN", "id": "O43772-1", "name": "Mitochondrial carnitine/acylcarnitine carrier protein", "aln": "-------------MAD---QPKPISPLKN---------LLAGGFGGVCLVFVGHPLDTVKVRLQTQPP--SLPGQPPMYSGTFDCFRKTLFREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQ----QKHPEDVLSYPQLFAAGMLSGVFTTGIMTPGERIKCLLQIQASS-GESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEWLKNIFTP-----EGKRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLG----------------------------FEVAMKFLN----------------------WATPNL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IN11-1", "uniprot_id": "A0AC58IN11_DANRE", "id": "A0AC58IN11-1", "name": "ribonuclease H", "aln": "-----------MDTVE---SDRRVSPLKN---------FVAGGFGGICLLLAGHPLDTIKVRLQTQ--------DCAVYKGTFDCFRKTVSKEGIFGLYKGMGAPLAGVTPMMALNFFGFGLGKELL----QRDPTVPATYTQIYLAGMLAGVCTTVIVAPGERIKCLLQILPLA-GRMKYTGPLDCAVRLYKQQGICSVYKGTILTLIRDVPSNGVYFLTYDYLKHYLTP-----DGECVHHLSTSRVLLAGGIAGMINWLIALPADVLKSNYQSATDGRY-QGVRHVLRTLLKEEGAQGLYKGFSAVMLRAFPANAEEQVDLSNVPREYHDLKRVFSKSRAASLPPHHPYDCAIDLLPGTSPPKGKLYSLSVPEREAKEKYISDSLAAKIIRPSSSPAGAGFFFVKKKDGSLCPCIDYRGLNSIMVKNKYPLPLMSSAFERLQGVNFFTKLDLRNAYHLVRIRPGDEWKTAFNTPRGHFEYCVLPFGLSNVLAVFQALVNDVLRDMIDQFIYIYPDDILIFSHSLQEHVQHVRRVLQRLLENGLYVKAEKCVFHAQSVQFLGHIVSVEGMRMDPEKIQAVVNWPTPDSRKALQRFLGFANFYWRFIRNFSQLATPLTNLTSSKTPFRWSNAAEAAFSKLKGCFVSARFS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQG4-1", "uniprot_id": "COLT_DROME", "id": "Q9VQG4-1", "name": "Congested-like trachea protein", "aln": "-----------MTTTENVSTERKANPVKS---------FLTGGFGGICNVLSGHPLDTIKVRLQTMPR--PAPGEQPLYRGTFDCAAKTIKNEGVRGLYKGMSAPLTGVAPIFAMCFAGYALGKRLQ----QRGEDAKLTYPQIFVAGSFSGLFSTLIMAPGERIKVLLQTQQGQGGERKYNGMIDCAGKLYKEGGLRSVFKGSCATMLRDLPANGLYFLVYEALQDVAKS-----KSE-TGQISTASTIFAGGVAGMAYWILGMPADVLKSRLQSAPEGTYKHGIRSVFKDLIVKDGPLALYRGVTPIMLRAFPANAACFFG----------------------------IELANKFFN----------------------IVAPNF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VM51-1", "uniprot_id": "MME1_DROME", "id": "Q9VM51-1", "name": "Mitochondrial magnesium exporter 1", "aln": "-----------MEEVE-ISTEKKSNPVKS---------FIAGGVGGMCNVLVGHPLDTIKVRLQTMPT--PPPGQPPRYKGVIDCAARTFRYEGFRGFYRGISAPLVGVTPIYAVDFAVYAAGKRLF----QTDDHIRLTYPQIFAAGALAGVCSALVTVPTDRIKVLLQTQTVSNGPLLYNGTIDTAAKLYRQGGIRSLFKGTCACILRDSPT-GFYFVTYEFLQELARK-----KSA-NGKISTTSTILSGGTAGIVFWTLAVPFDVLKSRLQSAPEGTYKHGIRSVFRNLMATEGPKALFRGILPILLRAFPSTAAVFFG----------------------------VELTNDLLK----------------------A----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12289-1", "uniprot_id": "CRC1_YEAST", "id": "Q12289-1", "name": "Mitochondrial carnitine carrier", "aln": "MSSDTSLSESSLLKEESGSLTKSRPPIKSNPVRENIKSFVAGGVGGVCAVFTGHPFDLIKVRCQNGQANSTVHAITNIIKEAKTQVKGTLFTNSVKGFYKGVIPPLLGVTPIFAVSFWGYDVGKKLVTFNNKQGGSNELTMGQMAAAGFISAIPTTLVTAPTERVKVVLQTSSKG-------SFIQAAKTIVKEGGIASLFKGSLATLARDGPGSALYFASYEISKNYLNSRQPRQDAGKDEPVNILNVCLAGGIAGMSMWLAVFPIDTIKTKLQASS--TRQNMLSATKEIYLQRGGIKGFFPGLGPALLRSFPANAATFLG----------------------------VEMTHSLFK------------------------KYGI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *.*. :::**.**:* :: ***:* :*** *. . *. :.. *:*:*: .*: **:*: *: * : **.* : : *: ** ::.: :: : .* :*:* :** . :: * : :: *: ..:**: : ** * ..** *: :. .. :. .:** *: * .* *.:*:. *::. : . . . : * .:: *. . ::*:**:.* .. : . .:: ", "identical_positions": 60, "similar_positions": 97, "identity": "9.22%" }, { "cls_id": "homologset.agr.SGD:S000005627", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62070-1", "uniprot_id": "RRAS2_HUMAN", "id": "P62070-1", "name": "Ras-related protein R-Ras2", "aln": "-MAAAGWRDGSGQ--------------EKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQ-----------------------------EQECPPS-----------------------------------------------------------PEPTRKEKDKKGCH--------------------CVIF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5BJU0-1", "uniprot_id": "Q5BJU0_RAT", "id": "Q5BJU0-1", "name": "", "aln": "-MAAAGWRDGSGQ--------------EKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQ-----------------------------EQECPPS-----------------------------------------------------------PEPTRKEKDKKGCH--------------------CVIF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62071-1", "uniprot_id": "RRAS2_MOUSE", "id": "P62071-1", "name": "Ras-related protein R-Ras2", "aln": "-MAAAGWRDGSGQ--------------EKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQ-----------------------------EQECPPS-----------------------------------------------------------PEPTRKEKDKKGCH--------------------CVIF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10833-1", "uniprot_id": "RRAS_MOUSE", "id": "P10833-1", "name": "Ras-related protein R-Ras", "aln": "MSSGAASGTGRGRPRGGGPGPRDPPPGETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICTVDGIPARLDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNKADLENQRQVLRSEASSFSASHHMTYFEASAKLRLNVDEAFEQLVRAVRKYQ-----------------------------EQELPPS-----------------------------------------------------------P-PSAPRKKDGGCP--------------------CVLL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z8L7-1", "uniprot_id": "RRAS_RAT", "id": "D3Z8L7-1", "name": "Ras-related protein R-Ras", "aln": "MSSGAASGTGRGRPRGGGPGPRDPPPGETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICTVDGIPARLDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFIEVSKLFTQILRVKDRDDFPIVLVGNKADLETQRQVLRSEASSFSASHHMTYFEASAKLRLNVDEAFEQLVRTVRKYQ-----------------------------EQELPPS-----------------------------------------------------------P-PSAPRKKDGRCP--------------------CVLL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10301-1", "uniprot_id": "RRAS_HUMAN", "id": "P10301-1", "name": "Ras-related protein R-Ras", "aln": "MSSGAASGTGRGRPRGGGPGPGDPPPSETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICSVDGIPARLDILDTAGQEEFGAMREQYMRAGHGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPVVLVGNKADLESQRQVPRSEASAFGASHHVAYFEASAKLRLNVDEAFEQLVRAVRKYQ-----------------------------EQELPPS-----------------------------------------------------------P-PSAPRKKGGGCP--------------------CVLL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04388-1", "uniprot_id": "RAS2_DROME", "id": "P04388-1", "name": "Ras-like protein 2", "aln": "------------------------MQMQTYKLVVVGGGGVGKSAITIQFIQSYFVTDYDPTIEDSYTKQCNIDDVPAKLDILDTAGQEEFSAMREQYMRSGEGFLLVFALNDHSSFDEIPKFQRQILRVKDRDEFPMLMVGNKCDLKHQQQVSLEEAQNTSRNLMIPYIECSAKLRVNVDQAFHELVRIVRKFQ-----------------------------IAER--------------------------------------------------------------PFIEQDYKKKGKRK--------------------CCLM-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P01119-1", "uniprot_id": "RAS1_YEAST", "id": "P01119-1", "name": "Ras-like protein 1", "aln": "-MQGNKST------------------IREYKIVVVGGGGVGKSALTIQFIQSYFVDEYDPTIEDSYRKQVVIDDKVSILDILDTAGQEEYSAMREQYMRTGEGFLLVYSVTSRNSFDELLSYYQQIQRVKDSDYIPVVVVGNKLDLENERQVSYEDGLRLAKQLNAPFLETSAKQAINVDEAFYSLIRLVRDDGGKYNSMNRQLDNTNEIRDSELTSSATADREKKNNGSYVLDNSLTNAGTGSSSKSAVNHNGETTKRTDEKNYVNQNNNNEGNTKYSSNGNGNRSDISRGNQNNALNSRSKQSAEPQKNSSANARKESSGGCCIIC", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P08646-1", "uniprot_id": "RAS1_DROME", "id": "P08646-1", "name": "Ras-like protein 1", "aln": "--------------------------MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAVNSAKSFEDIGTYREQIKRVKDAEEVPMVLVGNKCDLAS-WNVNNEQAREVAKQYGIPYIETSAKTRMGVDDAFYTLVREIRKD-------------------------------KDNKG------------------------------------------------------------RRGRKMNKPNRRFK--------------------CKML-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::****.*******:***:**.:** :********* * :*. . ***********:.***:****:*.*****:::.. ** :: . ** **** : .*::::*** ** :* .:. . . .::* *** :.**:** *:* :*. . * :: ", "identical_positions": 80, "similar_positions": 49, "identity": "24.39%" }, { "cls_id": "homologset.agr.SGD:S000005629", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61803-1", "uniprot_id": "DAD1_HUMAN", "id": "P61803-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "aln": "-----------MSASVVSVISRFLEEYLSST---------PQRLKLLDAYLLYILLTGALQFGYCLLVG-TFPFNSFLSGFISCVGSFILAVCLRIQINPQNKADFQGISPERAFADFLFASTILHLVVMNFVG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61804-1", "uniprot_id": "DAD1_MOUSE", "id": "P61804-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "aln": "-----------MSASVVSVISRFLEEYLSST---------PQRLKLLDAYLLYILLTGALQFGYCLLVG-TFPFNSFLSGFISCVGSFILAVCLRIQINPQNKADFQGISPERAFADFLFASTILHLVVMNFVG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61805-1", "uniprot_id": "DAD1_RAT", "id": "P61805-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "aln": "-----------MSASVVSVISRFLEEYLSST---------PQRLKLLDAYLLYILLTGALQFGYCLLVG-TFPFNSFLSGFISCVGSFILAVCLRIQINPQNKADFQGISPERAFADFLFASTILHLVVMNFVG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VLM5-1", "uniprot_id": "DAD1_DROME", "id": "Q9VLM5-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "aln": "------------MVELSSVISKFYNDYVQNT---------PKKLKLVDIYLGYILLTGIIQFVYCCLVG-TFPFNSFLSGFISTVSCFVLAVCLRLQANPQNKSVFAGISPERGFADFIFAHVILHLVVMNFIG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46964-1", "uniprot_id": "OST2_YEAST", "id": "P46964-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2", "aln": "MAKAPKANTPKVTSTSSAVLTDFQETFKTSKRAYFAQIEKYPKLKLIDTFCFFLVLLGVIQCTFIILIRDNFPFNAFLAGFIICVGQFVLLMSLRLQLCN----SFPGISKNRAFAEFIVASLILHFVCLHFIN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:: * : : .. :***:* : :::* * :* : *: .****:**:*** *. *:* :.**:* * *** :*.**:*:.* ***:* ::*:.", "identical_positions": 39, "similar_positions": 34, "identity": "29.1%" }, { "cls_id": "homologset.agr.SGD:S000005632", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70439-1", "uniprot_id": "STX7_MOUSE", "id": "O70439-1", "name": "Syntaxin-7", "aln": "------------------------------MSY-------TPGIGGDSAQLAQRISSNIQKITQCSVEIQRTLNQLGTPQDSPELRQLLQ----------QKQQYTNQLAKETDKYIKEFGSLP---TTPSEQRQRKIQKDRLVAEFTTSLTNFQKAQRQAAEREKEFVARVRASSRVSGGFPEDSSKEKNLVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDMIDSIEANVESAEVHVQQANQQLSRAADYQRKSRKTLCIIIFILVVRIVIICLIVWGLKG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70257-1", "uniprot_id": "STX7_RAT", "id": "O70257-1", "name": "Syntaxin-7", "aln": "------------------------------MSY-------TPGIGGDPAQLAQRISSNIQKITQCSAEIQRTLNQLGTPQDTPELRQQLQ----------QEQQYTNQLAKETDKYIKEFGFLP---TTPSEQRQRKIQKDRLVAEFTTALTNFQKVQRQAAEREKEFVARVRASSRVSGGFPEDSSKEKNFVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDVIDSIEANVESAEVHVQQANQQLSRAANYQRKSRKTLCIIILILVVGIVIIFFIVWGLKG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15400-1", "uniprot_id": "STX7_HUMAN", "id": "O15400-1", "name": "Syntaxin-7", "aln": "------------------------------MSY-------TPGVGGDPAQLAQRISSNIQKITQCSVEIQRTLNQLGTPQDSPELRQQLQ----------QKQQYTNQLAKETDKYIKEFGSLP---TTPSEQRQRKIQKDRLVAEFTTSLTNFQKVQRQAAEREKEFVARVRASSRVSGSFPEDSSKERNLVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDVIDSIEANVENAEVHVQQANQQLSRAADYQRKSRKTLCIIILILVIGVAIISLIIWGLNH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5F7-1", "uniprot_id": "A0ACD6B5F7_DANRE", "id": "A0ACD6B5F7-1", "name": "Syntaxin-12", "aln": "MIVCFLSIHFDFCERSSASPPHLSITVTVIMSYGMMDSSHSQSQPRDFNNLTQTCSSNIQKITQNTGQIKSMLFQLGTRPDTPELQDRLQ----------QVQHYTNQLAKETNRHLKDLGTLPQP-QSPSEQRQQRIQKDRLMNDFSAALNNFQVVQRRAAERERESVARARAGSRFQ---VDELNQDEQLVTFEKNEGWRMQTEEEPVTEEDLELIKERETNIRQLESDIMDVNQIFKDLAVMIHDQGDMIDSIEANVESAEVHVERGAEQLQHAAYYQRKSRKRMCILALVLSLVATIFAIIIWQAIR-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VU45-1", "uniprot_id": "Q9VU45_DROME", "id": "Q9VU45-1", "name": "", "aln": "MSKALNNPGGNGGGGGPHRDYGAMADSTPEVSFAAAGGS-SGFSPTEFMSLSEDIGHNITAIHSSTKQLEKQLKLIGTSKEQPNLREKVH----------TINTKCNARVQTTSQDLQRLQAVVR-----HGDRQQKLQLEKLTREFHGVVEKYSNLQRRISSAMRQTLQQAQQ------------FADQVVETNARAELLQQQRLEQAHLQQEHDMLDDRRRQVEQIESDIIDVNQIMTQLSGLVHDQGQQMDFIENSIEQTAANVEDGTSELAKAARSRQSYRRKILILLVIAVIIGLIVTGVIVAKLNS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12241-1", "uniprot_id": "VAM3_YEAST", "id": "Q12241-1", "name": "Syntaxin VAM3", "aln": "-----------------MSFFDIEAQSSKGNS--------QQEPQFSTNQKTKELSNLIETFAEQSRVLEKECTKIGSKRDSKELRYKIETELIPNCTSVRDKIESNILIHQNGKLSADFKNLKTKYQSLQQSYNQRKSLFPLKTPISPGTSKERKDIHPRTEAVRQDPESSYISIKVNEQSPLLHNEGQHQLQLQEEQEQQQQGLSQEELDFQTIIHQERSQQIGRIHTAVQEVNAIFHQLGSLVKEQGEQVTTIDENISHLHDNMQNANKQLTRADQHQRDRNKCGKVTLIIIIVVCMVVLLAVLS----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . :: . * : . : :: :*: : :*: :. : * : ..: : : . ::: . * : : : :. :: . : * .: : : : .:* .: ::.: : ::* *: :*. ::::**: : *: .:. ::: . .:* :* ::. .: : .: : :. : ", "identical_positions": 16, "similar_positions": 86, "identity": "5.13%" }, { "cls_id": "homologset.agr.SGD:S000005633", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4L0E8-1", "uniprot_id": "RGS18_RAT", "id": "Q4L0E8-1", "name": "Regulator of G protein signaling 18", "aln": "------------------------MDMSLVFFSHLNMCESKEKTFFKLMHGSGKEETNIEAKIRAKEKRNRLSLLLQRPDFHGETHT---SRSALLAKETRVSSEEALKWAESFDKLLSHRDG---------------------VDAFTRFLKTEFSEENIEFWVA-----CEDFKKCTEPQQLILKAKSIYEKFIKNDAPKEVN-LDFHTKEVITKSIAQP------TLHSFDAAQSRVCQLMEHDSYKRFLKSEIYLHLIEGRPQRPTNLRRRSRSFTYNEFQDVKSDVAIWL--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PG4-1", "uniprot_id": "RGS18_MOUSE", "id": "Q99PG4-1", "name": "Regulator of G protein signaling 18", "aln": "------------------------MDMSLVFFSQLNMCESKEKTFFKLMHGSGKEETSIEAKIRAKEKRNRLSLLLQRPDFHGETQA---SRSALLAKETRVSPEEAVKWAESFDKLLSHRDG---------------------VDAFTRFLKTEFSEENIEFWVA-----CEDFKKCKEPQQIILKAKAIYEKFIQNDAPKEVN-IDFHTKEVIAKSIAQP------TLHSFDTAQSRVYQLMEHDSYKRFLKSETYLHLIEGRPQRPTNLRRRSRSFTYNDFQDVKSDVAIWL--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NS28-1", "uniprot_id": "RGS18_HUMAN", "id": "Q9NS28-1", "name": "Regulator of G protein signaling 18", "aln": "------------------------METTLLFFSQINMCESKEKTFFKLIHGSGKEETSKEAKIRAKEKRNRLSLLVQKPEFHEDTRS---SRSGHLAKETRVSPEEAVKWGESFDKLLSHRDG---------------------LEAFTRFLKTEFSEENIEFWIA-----CEDFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVN-LDFHTKEVITNSITQP------TLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLMEGRPQRPTNLRRRSRSFTCNEFQDVQSDVAIWL--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O08850-1", "uniprot_id": "RGS5_MOUSE", "id": "O08850-1", "name": "Regulator of G protein signaling 5", "aln": "------------------------------------MCKG----LAALPHS---------CLERAKEIKIKLGILLQKPDSAVDLVIPYNEKPEKPAKAHKPSLEEVLQWRQSLDKLLQNSYG---------------------FASFKSFLKSEFSEENLEFWVA-----CENYKKIKSPIKMAEKAKQIYEEFIQTEAPKEVN-IDHFTKDITMKNLVEP------SPRSFDLAQKRIYALMEKDSLPRFVRSEFYKELIK----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49800-1", "uniprot_id": "RGS5_RAT", "id": "P49800-1", "name": "Regulator of G protein signaling 5", "aln": "------------------------------------MCKG----LAALPHS---------CLERAKEIKIKLGILLQKPDSAVDLVIPYNEKPEKPAKAHKPSLEEVLQWRQSLDKLLQSNYG---------------------FASFKSFLKSEFSEENLEFWVA-----CENYKKIKSPIKMAEKAKQIYEEFIQTEAPKEVN-IDHFTKDITMKNLVEP------SPHSFDLAQKRIYALMEKDSLPRFVRSEFYKELIN----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15539-1", "uniprot_id": "RGS5_HUMAN", "id": "O15539-1", "name": "Regulator of G protein signaling 5", "aln": "------------------------------------MCKG----LAALPHS---------CLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNNYG---------------------LASFKSFLKSEFSEENLEFWIA-----CEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVN-IDHFTKDITMKNLVEP------SLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELIK----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41220-1", "uniprot_id": "RGS2_HUMAN", "id": "P41220-1", "name": "Regulator of G protein signaling 2", "aln": "-------------------------MQSAMFLAVQHDCRPMDKSAGSGHKSEEKRE--KMKRTLLKDWKTRLSYFLQNSSTPGKPKT---GKKSKQQAFIKPSPEEAQLWSEAFDELLASKYG---------------------LAAFRAFLKSEFCEENIEFWLA-----CEDFKKTKSPQKLSSKARKIYTDFIEKEAPKEIN-IDFQTKTLIAQNIQEA------TSGCFTTAQKRVYSLMENNSYPRFLESEFYQDLCK-KPQITTEPHAT----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N0Y4-1", "uniprot_id": "A0A8M1N0Y4_DANRE", "id": "A0A8M1N0Y4-1", "name": "", "aln": "--------------------------MDRLTKMRTASPDSGREHLINYRNSEEMTE-----QSQIKKKSWRPRIFFSTLPLKESQNT------SPQKKSHLPTTEEVSQWAQSLDNLLSSKCG---------------------LNFFRLFIKSELCEENLDFWLA-----CEEFRKIRSRSKLKSKAKSIYNEFIKPDSPKEIN-LDYNMKEMLQQSLLIP------TPCTFKVAQHRVLYLMEHNSYPRFLESELYQTLCRLAEGKQ----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1ND70-1", "uniprot_id": "A0A8M1ND70_DANRE", "id": "A0A8M1ND70-1", "name": "", "aln": "--------------------------------------------MPTILST--------EIENMNKEDKATNPRRLEKWRFR-------------CPLTEKINPGETSQWSQSLENLLRSKYG---------------------MATFHTFLKSEFSDENIEFWLV-----CEDFKKTRSLSRLSSRAKKIFERYIKAEAPKEIN-IDHVTRELIKQNVHAP------TKVCFDEAQRIVFGLMERDSYPRFLRSDMYRSLLESVSNGIKV--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9UGC6-1", "uniprot_id": "RGS17_HUMAN", "id": "Q9UGC6-1", "name": "Regulator of G protein signaling 17", "aln": "------------------------MRKRQQSQNEGTPAVSQAPGNQRPNNTCCFCWCCCCSCSCLTVRNEERGENAGRPTHTTKMES-----IQVLEECQNPTAEEVLSWSQNFDKMMKAPAG---------------------RNLFREFLRTEYSEENLLFWLA-----CEDLKKEQNKKVIEEKARMIYEDYISILSPKEVS-LDSRVREVINRNLLDP------NPHMYEDAQLQIYTLMHRDSFPRFLNSQIYKSFVESTAGSSSES-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99188-1", "uniprot_id": "RGS2_YEAST", "id": "Q99188-1", "name": "Regulator of G protein signaling 2", "aln": "MASVPSLCDILIPLEKNSRSDGDAESSNTVLIQLRKGHHERMRSPYTIQKFYKFLKRAHCEENLEFFEKAHQFLQLKQNRSISEEKLLEVWNKSLYIKYIAVDSPKECNFSQDTREIFEKCFANNEVPADVDVLCAISHVMGLLMDGYHRFVSSVNEKKYSATYAHNDSATEQDLKNESTTSFSSLGVEDISEDRNSYLKKPDINGLSTIIQETSANTTNESQCSDRTSRPSESSSSLNTTSSTYKNTSTRNLQKPQNTGILNSGKGLLQKLNFVKKRKSFKQPSGVICSHYNSNVQNRLKGQNSHQQR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : ::: . : *: : .: : :: :: .. * . ::. :. : .. . . :. .:: * :.. : . ", "identical_positions": 3, "similar_positions": 40, "identity": "0.97%" }, { "cls_id": "homologset.agr.SGD:S000005635", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CHC4-1", "uniprot_id": "SYNJ1_MOUSE", "id": "Q8CHC4-1", "name": "Polyphosphatidylinositol phosphatase SYNJ1", "aln": "-MAFSKGFRIYHKLDPP-PFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYAKVLDAYGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLR-------------------------VDASDEDRISEVRKVLNSGNFYFAWSASGVSLDLSLNAHRSMQEHTTD-NRFFWNQSLHLHLKHYGVNCDD----------WLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVIYLDDCVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKDLYGKQIVVNLLGSKEGEHMLSKAFQSHLKAS---EHASDIHMVSFDYHQMVKGGKAEKLHSILKPQVQKFLDYG-FFYFDGSE-VQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR--FQEVFRSMWSVNGDSISKIYAGTGALEG-------KAK---LKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGSLRVSEQTLQS---------ASSKVLKNMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVNASTTNQKLWAVELQKTISR-DNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFVEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQN---WDSLIAGDQLINQKNAGQIFRGFLEGKVTFAPTYKYDLFSEDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQKIYKEVIAVQGPPDGTVLVSIKS-SAQESTFFDDALIDELLRQFAHFGEVILIRFVEDKMWVTFLEGSSALNALSLNGKELLNRTITITLKSPDWIKHLEEEMSLEKISVTLPSSAS-STLLGEDAEVA-ADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTVPEYSAPSLPIRPSRAPSRTPGPPSS-----------QGSPVDTQPAA---QKDSSQTLEPKRPPPPRPVAPPARPAPPQRPPPPSGARSPAPARKEFGGVGAPPSPGVARREIEAPKSPGTARKDNIGRNQPS------------PQAGLAG-------PGPAGYGAARPTIPARAGVISAPQSQARVCAGRPTPDSQSKPSETLKGP-AVLPEPLKPQAAFPQQPSLPTPAQKLQDPLVP--------------IAAPTMPPSGPQPNLETP---------PQPPPRSRSSQSLPSDSSPQLQQEQPTG-QVKINGISGVKQEPTLKSDPFEDLS----LSVLAVSKAQPSVQISPVLTPDPKM-LIQLPSASQSQVNPLSSVSCMPTRPPGPEESKSQESMGSSANPFPS-LPCRNPFTDRTAAPGNPFRVQSQESEATSWLSKEEPVPNSPFPPLMPLSHDTSKASSSLGGFEDNFDLQSQSTVKTSNPKGWVTFDEDDNFPTT--GKSKSVCPDLVGNAPASFD-------DDWSKGASVSFCVLPARRPPPPPPPVPLLPPGTTSSAGPSTTLPSKAPSTLDFTER", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62910-1", "uniprot_id": "SYNJ1_RAT", "id": "Q62910-1", "name": "Polyphosphatidylinositol phosphatase SYNJ1", "aln": "-MAFSKGFRIYHKLDPP-PFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYAKVLDAYGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLR-------------------------VDASDEDRISEVRKVLNSGNFYFAWSASGVSLDLSLNAHRSMQEHTTD-NRFFWNQSLHLHLKHYGVNCDD----------WLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVIYLDDCVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKDLYGKQIVVNLLGSKEGEHMLSKAFQSHLKAS---EHASDIHMVSFDYHQMVKGGKAEKLHSVLKPQVQKFLDYG-FFYFDGSA-VQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR--FQEVFRSMWSVNGDSISKIYAGTGALEG-------KAK---LKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGSLRVSEQTLQS---------ASSKVLKNMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVNASTTNQKLWAVELQKTISR-DNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFVEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQN---WDSLIAGDQLINQKNAGQIFRGFLEGKVTFAPTYKYDLFSEDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQKIYKEVIAVQGPPDGTVLVSIKS-SAQENTFFDDALIDELLQQFAHFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITITLKSPDWIKTLEEEMSLEKISVTLPSSTS-STLLGEDAEVS-ADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTAPEYSAPSLPIRPSRAPSRTPGPLSS-----------QGAPVDTQPAA---QKESSQTIEPKRPPPPRPVAPPARPAPPQRPPPPSGARSPAPARKEFGGVGAPPSPGVTRREMEAPKSPGTARKDNIGRNQPS------------PQAGLAG-------PGPSGYGAARPTIPARAGVISAPQSQARVSAGRLTPESQSKPLETSKGP-AVLPEPLKPQAAFPPQPSLPTPAQKLQDPLVP--------------IAAP-MPPSIPQSNLETP---------PLPPPRSRSSQSLPSDSSPQLQQEQPTGQQVKINGACGVKQEPTLKSDPFEDLS----LSVLAVSKAQPSAQISPVLTPDPKM-LIQLPSASQSKVNSLSSVSCMLTMPPVPEQSKSQESVGSSANPFPS-LPTRNPFTDRTAAPGNPFRVQSQESEATSWLSKEEPVSNSPFPPLMPLSHDMSKPSSSLDGFEDNFDLQSQSTVKTSNPKGWVTFDEDEDFPTK--GKSRSVYPDSLGNTAASFD-------DDWSKGTNVSFCVLPARRPPPPPPPVPLLPPGTTSSAGPSTTLSSKASPTLDFTER", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43426-1", "uniprot_id": "SYNJ1_HUMAN", "id": "O43426-1", "name": "Polyphosphatidylinositol phosphatase SYNJ1", "aln": "-MAFSKGFRIYHKLDPP-PFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAYGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLR-------------------------IDSSDEDRISEVRKVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTD-NRFFWNQSLHLHLKHYGVNCDD----------WLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKAS---EHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLDYG-FFYFNGSE-VQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR--FQEVFRSMWSVNGDSISKIYAGTGALEG-------KAK---LKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGSLRVSEQTLQS---------ASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISR-DNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQN---WDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKS-SLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTS-STLLGEDAEVA-ADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSA-----------QSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPS------------PQAGLAG-------PGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGS-TFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVP--------------VAAP-MPQSGPQPNLETP---------PQPPPRSRSSHSLPSEASSQPQ--------VKTNGISDGKRESPLKIDPFEDLS----FNLLAVSKAQLSVQTSPVPTPDPKR-LIQLPSATQS--NVLSSVSCMPTMPPIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDFGVK--GKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPP--PVPLLPPGTSPPVDPFTTLASKASPTLDFTER", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B1N6-1", "uniprot_id": "A0A8M2B1N6_DANRE", "id": "A0A8M2B1N6-1", "name": "Synaptojanin-1", "aln": "-MAFSKGYRIYHKLDPP-PYSVIVETRNREECLMFESGAVAVLSAAEKETIKASYTKMLDAYGILGVLRLNLGDSMLHSLVVVTGCSSVGKVQDSEVFRVTGTDFVSLK-------------------------NDPTDEDRIADVRKVLNSGNFYFAWSSTGVSLDLSLNAHRRIREDTSD-NRFFWNQSLHLHLKHYGVNCDD----------WLLRLMCGGVEIRTIYAGHKQAKACVISRLSSERAGTRFNVRGTNDDGQVANFVETEQIIFLDDKVSSFIQIRGSIPLFWEQPGIQVGSHRVKLSRGFEANAPAFERHFSALKRLYGKQLIINLLGMKEGEHMLSKAFQSHLKAS---EHSNAVKMLNFDYHQMVKGGKTEKLQTVLKPQISKFVEDCDFFYYSGETGIQRCQSGTIRSNCLDCLDRTNSVQAFIALEMLPKQLEAMGLTEKPQLVAR--FQEVFRSMWSTNGDSISKIYAGTGALDG-------KAKGGKLKDGARSVTRTIQNNFFDSSKQEAIDILRLGSTLNSDLADKARALLTTSSLYVSEPILQS---------ASPRVLLGMCQNHFKYTRPKKIRVCVGTWNVNGGKQFRSIAFRNHTLNDWLLDAPKKAGHPEFQDVKNNPVDIFAIGFEEMVELNAGNIVSASTTNQKLWAAELQKNISR-DQRYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGGVAIRMLFHTTSICFVCSHFAAGQSQVKERNDDYNEIARKLSFPMGRLLYSHDYVFWCGDFNYRINIPNEEVKELIRQQN---WDALIGGDQLVEQKNAGQVFRGFIEGKLDFAPTYKYDLFSEDYDTSEKCRTPAWTDRVLWKRRKWNFDKTAEELELNVVGAPVNEEEQYPWSPGDLKYYGRAELKTSDHRPVVAIIDVDILEVDPEARHQVYKEVIALQGPPDGTILVSLCS-SGPDD-YFDDALIDDLLDKFANFGEVILIRFVEEKMWVTFLEGYSALAALSLSGSTVNGKTIDIRLRSPGWIKSLEEEMSVERICGSIPTSTS-STLLAENSDLG-EEYDMEGDVD---EEVEDILPQHLQPGAGMDLSASPATSPRTSPCPSPTHG---EPAPPIRPSRAPPRTAGPPQGGLSPASIRRELAGSPVDGQPAG----APFSQGLEPKRPPPPRPNAPPARPAPPQRPPPPSGGRSPTPVRKDSAGFAEPLNLEFDLTDNEGQKSPALARADAAGRGQATGPAPGGIPRPIPPRAGVISVTPQARPPPPAHPGAPRPTAEVHPGAP-RPSPDNHPGAPRPTAEPQSKPSELPLGPPPTLPGPVRPQMTSPMQPQSVSPVQPPVQPQLPPPIQSQLPPPMQPTLPAPLMPQQAPQTSAGAAAAPQPGLASPKPPPRSRSSHALPPESAPAPT--------TQAKNMNGVQREAQWNLDPFDMLNPQSLFQNTPFTASLPRSSSSSTSTPSPSSSSSTLPSNLSLFSAPDTSSASCLLAPPAPSRSKSQETLRCSPNPFLTDIQPR-PNSTNPFTSGLQFSPRRS---LTPDFYTQMQASKPDFNRAMSAVGHSSTLPPTFS--RQQSLVTATAPAPNKQTQKWVTFDDDLDFLSKRVGTGPLASPLPFPQTQSSFP--------SSGFGMDNNWASLPTSAFPAIPPPVPTR----TNTSIKNAQLPSRN----DFTER", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9D2G5-1", "uniprot_id": "SYNJ2_MOUSE", "id": "Q9D2G5-1", "name": "Polyphosphatidylinositol phosphatase SYNJ2", "aln": "-MALSKGLRLLARLDPTGPSSVLLEARGRGDCLLFEAGAVATLAPEEKEVIKGLYSKLTDAYGCLGELRLQSGGVPLSFLVLVTGCMSVGRIPDAEIYKITATELYPLQ-------------------------EEAKEEDRLPTLKKILSSGVFYFAWPNDGACFDLTIRAQKQGDDGSEWGTSFFWNQLLHVPLRQHQVNCHN----------WLLKVICGVVTIRTVYASHKQAKACLISRISCERAGARFLTRGVNDDGHVSNFVETEQTIYMDDGVSSFVQIRGSVPLFWEQPGLQVGSHHLRLHRGLEANAPAFERHMVLLKEQYGKQVVVNLLGSRGGEEVLNRAFKKLLWAS---CHAGDTPMINFDFHQFAKGRKLEKLENLLRPQLQLHWEDFGVFAK-GENVSPRFQKGTLRMNCLDCLDRTNTVQCFIALEVLHLQLESLGLNSKP-IIDR--FVESFKAMWSLNGHSLSKVFTGSRALEG-------KAKVGKLKDGARSMSRTIQSNFFDGVKQEAIKLLLVGDVYNEESTDKGRMLLDNTALL-----------------ATPRILKAMTERQSEFTNFKRIQIAVGTWNVNGGKQFRSNLLGTAELTDWLLDAPQLSGAVDSQDDGS-PADVFAIGFEEMVELSAGNIVNASTTNRKMWGEQLQKAISR-SHRYILLTSAQLVGVCLYIFVRPYHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQLHSTSFCFVCSHLTAGQSQVKERNEDYREITHKLSFPSGRNIFSHDYVFWCGDFNYRIDLTYEEVFYFVKRQD---WKKLMEFDQLQLQKSSGKIFKDFHEGAVNFGPTYKYDVGSAAYDTSDKCRTPAWTDRVLWWRKKHPYDKTAGELNLLDSDLDGDPQIRHTWSPGTLKYYGRAELQASDHRPVLAIVEVEVQEVDVGARERVFQEVSSVQGPLDATVVVNLQSPTLEEKNEFPEDLRTELMQTLGNYGTIILVRINQGQMLVTFADSHSALSVLDVDGMKVKGRAVKIRPKTKDWLEGLREELLRKRDSMAPVSPTANSCLLEENFDFSSLDYESEGDVLE---EDEDYLVDGFGQPVVSDSELGGDNSSDTMSSLTPASK---SPALAKKKQHPTYK------------------------------------------------------------------AGLMVKKSASDASISSGTHGQYSILQTAKLLPGAPQQPPKARTGISKPYN----------VKQIKTTN--------AQEAEAAIRCLLEASGGVP-----ESAPGAIPLRNQGSSKP-EATLGP-PALPRRPAPRVPTMKKPTLRRTGKPMLPEENFE-------------PQPVHFTMASQEMNLETP-----------PPITATPIPPVPKPRTLQPG-----------KGVEG--RPSSGKPEPDEAPS-----VTGTVESPPPEAQEAPSLAPKVPP-------------RRKKSAPAAFHLQVLQNNSQVLQGLTCSSS------------SPPSLKPDTHPLCLQVALGTSSARSPETHGPRVTEPEAASFHGNYP----------DPFWSLLHHPKLLNN-TWLSKSSEPLDVGSR--------NPERTHTEPAQVN------------------ASLAERGLPPDHGGKDLSHWVTASNKDKRTTLGV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O55207-1", "uniprot_id": "SYNJ2_RAT", "id": "O55207-1", "name": "Polyphosphatidylinositol phosphatase SYNJ2", "aln": "-MALSKGLRLLARLDPTGPSSVLLEARGRGDCLLFEAGAVATLAPEEKEVIKGLYGKPTDAYGCLGELSLKSGGVPLSFLVLVTGCTSVGRIPDAEIYKITGTEFYPLQ-------------------------EEAKEEDRLPALKKILSSGVFYFAWPNDGACFDLTIRAQKQGDDCSEWGTSFFWNQLLHVPLRQHQVNCHD----------WLLKVICGVVTIRTVYASHKQAKACLISRISCERAGARFLTRGVNDDGHVSNFVETEQAIYMDDGVSSFVQIRGSVPLFWEQPGLQVGSHHLRLHRGLEANAPAFERHMVLLKEQYGQQVVVNLLGSRGGEEVLNRAFKKLLWAS---CHAGDTPMINFDFHQFAKGRKLEKLENLLRPQLKLHWDDFGVFAK-GENVSPRFQKGTLRMNCLDCLDRTNTVQCFIALEVLHLQLESLGLNSKP-ITDR--FVESFKAMWSLNGHGLSKVFTGSRALEG-------KAKVGKLKDGARSMSRTIQSNFFDGVKQEAIKLLLVGDVYNEESTDKGRMLLDNTALLGLGSNKQNSLSGMLDGKATPRILKAMTERQSEFTNFKRIQIAMGTWNVNGGKQFRSNLLGTTELTDWLLDAPQLSGAVDSQDDGG-PADIFAVGFEEMVELSAGNIVNASTTNRKMWGEQLQKAISR-SHRYILLTSAQLVGVCLYIFVRPYHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQFHSTSFCFICSHLTAGQSQVKERNEDYREITHKLSFPSGRNIFSHDYVFWCGDFNYRIDLTYEEVFYFVKRQD---WKKLMEFDQLQLQKSSGKIFKDFHEGTINFGPTYKYDVGSAAYDTSDKCRTPAWTDRVLWWRKKHPYDKTAGELNLLDSDLDGDANIRHTWSPGTLKYYGRAELQASDHRPVLAIVEVEVQEVDVGARERVFQEVSSVQGPLDATVIVNLQSPTLEERNEFPEDLRTELMQTLGNYGTIILVRINQGQMLVTFADSHSALSVLDVDGMKVKGRAVKIRPKTKDWLEGLREELIRKRDSMAPVSPTANSCLLEENFDFTSLDYESEGDVLE---DDEDYLADEFGQPVVSDSELGGDDSSDTMSASTPASK---SPALAKKKQHPTYKDDADLMT-------------LKLELEVAGNFRHRSPSRSLSVPNRPRP--------PHPPQRPPPPTGLMVKKSASDASISSGTHGQYSILQTAKLLPGAPQQPPKARTGISKPYN----------VKQIKTTN--------AQEAEAAIRCLLEAGGGVP-----ESAPGATPLRNQGSSKP-EASLGP-PVLPRRPVPRVPTMKKPTLRRTGKPMLPEEQCE-------------QQPVHFTMASQEMNLETP-----------PPITA-PIPPVPKPRTFQPG-----------RGVER--RPSGGKPEPDDAPP-----VTGAVELSSPEAPEAPSLAPKVPP-------------RRKKSAPAAFHLQVLQSNSQLLQGLTCSSS------------SPSPPKPDTPLLYPQMALGTSSAISPETDGPRVTEPEAASFHGDYP----------DPFWSLLHHPKLLNNNTWLSKSSEPLDLGSR--------TPERTHTDSAQVN------------------ASVVERGLPPDHGGKDFSHWMAASNKDKRTTLGV-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12271-1", "uniprot_id": "INP53_YEAST", "id": "Q12271-1", "name": "Polyphosphatidylinositol phosphatase INP53", "aln": "MIIFVSEEPERRLAIVSNLYALVLKPVGKK----PSDKPLCAIELLQKNDLKKYGFKRLTSHEIFGVIGLIEVNGLLFVGAITGKSKVAQPCPGETVNKIFAVDFFCLNDNSWDFIEIDSSGYPVLPETASTEYQDALPKHPCYELKKLLSNGSFYYSSDFDLTSTLQHRGYGQHSLSTDTYEEEYMWNSFLMQEMITYRDHLDTNLKQILDDEGFLTTVIRGFAETFVSYVKKLKVALTIISKQSWKRAGTRFNARGVDDEANVANFVETEFIMYSSQYCYAFTQIRGSIPVFWEQGTSLIN-PRVQITRSFEATQPVFDKHIMKSVEKYGPVHVVNLLSTKSSEIELSKRYKEHLTHSKKLNFNKDIFLTEFDFHKETSQEGFSGVRKLIPLILDSLLSSGYYSYDVREKKNISEQHGIFRTNCLDCLDRTNLAQQIISLAAFRTFLEDFRLISSNSFIDDDDFVSKHNTLWADHGDQISQIYTGTNALKSSFSRKGKMSLAGALSDATKSVSRIYINNFMDKEKQQNIDTLLGRLPYQ-----KAVQLYDP---------------------VNEYVSTKLQSMSDKFTSTSNINLLIGSFNVNG-------ATKKVDLSKWLFPIG-----------EKFKPDIVVLGLQEVIELSAGSILNADYSKSSFWENLVGDCLNQYDDKYLLLRVEQMTSLLILFFVKADKAKYVKQVEGATKKTGFRGMAGNKGAVSIRFEYGATSFCFVNSHLAAGATNVEERRSDYESIVRGITFTRTKMIPHHDSIFWLGDMNYRINLPNEDVRRELLNQEEGYIDKLLHFDQLTLGINSGSVFEGFKEPTLKFRPTYKYDPGTGTYDSSEKERTPSWTDRIIYKGE-----------------------------NLLPLSYSDAPIMISDHRPVYAAYRAKITFVDDKERLSLKKRLFTEYKQEHPEEPGSLIS---------------------------DLLSLDLDNKSTDGFKSSSESSLLDIDPIMAQPTASSVASSSP--VSSASASLQPVRTQNSSQSRTP---------------------------IKKPVLRPPPPPAHKSVSAPAPSTSKEKSPTPQTSTASLSSVTKNIQENKPLAQNR----------------------------------------------------------RIPPPGFSQNILTPKSTSNLASPMSSKVDLYNSASESTRSAQDAR-------------------------------------------------------------QQTPTAFAASRDVNGQP-EALLGD----ENPIEPEEKAKLNHMTLDSWQPLTPK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . :::::. : . .:..: :*: :* * :: :* : * . * .:. . . : :: ..:: *. :. :. ::*:*..* **:: . : . ::**. * : : : . :* :: * . . *. : :. :**: * :***:** .**.:*:.:*:****** :: .: :* *****:*:**** :. :::: *.:**. *.*::*: ** ::***. : .* *.: ::. * * . : .**:*: .. . :..:: :. . . * * .* ********** .* ::.* : ** : * .. : * . ..::*: :*. :*::::*: **.. : *.*.::*::* .**:* **: *. * : *. * .. : : . ::: ..*.: :*::**** . *..**: *:..:*::*::**.**.*:.*. :: .:* : . :.: ..:*:** *:..: : .*::. :. ::::* * ***: * :****.*.**: :**:**: **::** ::*:**..*: .*.: ::*. : : ** :** **:****::. *:* : .*: . *: *** .:*.:*..* * : * ****** : **:*:* ***:****::: . *. * : ****** * .: *: * : :.: : . .: * *: : : . .. * *.:. : : : :. .: : : : :. : * . * . . .: : : .:. : . . . . . :. . . * : ..:. * * *. : . : ", "identical_positions": 214, "similar_positions": 339, "identity": "12.46%" }, { "cls_id": "homologset.agr.SGD:S000005636", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3V3E1-1", "uniprot_id": "UBS3A_MOUSE", "id": "Q3V3E1-1", "name": "Ubiquitin-associated and SH3 domain-containing protein A", "aln": "---------------------MAAGETQLYAKVSNKLKGRSTP------SLLDPLLAMGFPTHTALKALAATGRKTAEAAADWLHGHCNDPSLDDPIPQEYALFLCPTGPLLEKLQEFWRESRRQCAKNRAHEVFPHVTLCDFFTCEDQKVECLYEALRRAGDRILGSFPTLVPLVLHSSISYLGFFINDSPADAIREFAMAFATEAA--VLAD--------------------------------------CTIKPCTKQLHLTLAHKFYPHHQRTLEQLAKAIQPSHSCQWTAALYSRDMRFVHYQTLKALFQYKPQNADELMLSAGDYIFVDPTQQEEASEGWAIGISHRTGCRGFLPENYTERANEADTWVKHRTYTFNLAMDLNSR----------------------------KDFE-----ASCRGNGEPHTPSMSKSVSSIQALQATIS-------------------------------------------------------------------RRGILVVRHGERVDQVFGKSWLQQCTTADGKYYRPDLNFPRSLPRRSNGIKDFENDPPLSSCGIFQARLAGEALLDSGVRVTAVFASPALRCVQTAKHILEELKLEKKLKIRVEPGIFEWMKWEASKATLTFLTLEELKEANFNVDLDYRPALPRCSLMP--AESYDQYVERCAVSMGQIINTCPQDMGITLIVSHSSALDSCTRPLLGLPPRECGDFAQLVRKIPSLGMCFCEENREDGKWDLVNPPVKTLTHGANSVFNWRNWISSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L9L6-1", "uniprot_id": "A0ABK0L9L6_RAT", "id": "A0ABK0L9L6-1", "name": "Ubiquitin-associated and SH3 domain-containing protein A", "aln": "MSALASSPPVSRRLVYGKQEGMAAGETQLYAKVSNKLKGRSTS------SLLDPLLALGFPTHTALKALAATGMKTAEEAADWLHGHCSDPSLDDPIPQEYALFLCPTGPLLEKLQEFWRESRRQCAKNKAHEVFPHVTLCDFFTCEDQKVECLYEALRRAGDRILGSFPALVPLVLHSSISYLGFFINDSPADVIRDFAMAFATEAS--ALAD--------------------------------------CTIKPCTKQLHLTLAHKFYPHHQRTLEQLARAIQPSHTCQWTAALYSRDMRFVHYQTLKALFQYKPQNADELMLSPGDYIFVDPTQQEEASEGWAIGISHRTGCRGFLPENYTERANEADTWVKHRTYTFSLAMDLNSR----------------------------KEFE-----ASSRRNGDSHTPSVSRSISDIQALQATIA-------------------------------------------------------------------RRGVLVIRHGERVDQVFGKSWLHQCTTTDGKYYRPDLNFPRSLPRRSNGIKDFENDPPLSSCGIFQARLAGEALLDSGVRVTAVFASPALRCVQTAKHILEELKLERRLKIKVEPGIFEWMKWEAGKATLTFLTLEELKEADFNVDLDYRPAFPCCSLLP--AESYDQYVERCAVSMGQIINTCPQDMGITLIVSHSSALDSCTRPLLGLPPRECGDFAQLVRKIPSLGMCFCEENKEDGKWDLVNPPVKTLTHGANSVFNWRNWISSN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57075-1", "uniprot_id": "UBS3A_HUMAN", "id": "P57075-1", "name": "Ubiquitin-associated and SH3 domain-containing protein A", "aln": "---------------------MAAGETQLYAKVSNKLKSRSSP------SLLEPLLAMGFPVHTALKALAATGRKTAEEALAWLHDHCNDPSLDDPIPQEYALFLCPTGPLLEKLQEFWRESKRQCAKNRAHEVFPHVTLCDFFTCEDQKVECLYEALKRAGDRLLGSFPTAVPLALHSSISYLGFFVSGSPADVIREFAMTFATEAS--LLAGTSVSRFWIFSQVPGHGPNLRLSNLTRASFVSHYILQKYCSVKPCTKQLHLTLAHKFYPHHQRTLEQLARAIPLGHSCQWTAALYSRDMRFVHYQTLRALFQYKPQNVDELTLSPGDYIFVDPTQQDEASEGWVIGISQRTGCRGFLPENYTDRASESDTWVKHRMYTFSLATDLNSR----------------------------KDGE-----ASSRCSG-EFLPQTARSLSSLQALQATVA-------------------------------------------------------------------RKSVLVVRHGERVDQIFGKAWLQQCSTPDGKYYRPDLNFPCSLPRRSRGIKDFENDPPLSSCGIFQSRIAGDALLDSGIRISSVFASPALRCVQTAKLILEELKLEKKIKIRVEPGIFEWTKWEAGKTTPTLMSLEELKEANFNIDTDYRPAFPLSALMP--AESYQEYMDRCTASMVQIVNTCPQDTGVILIVSHGSTLDSCTRPLLGLPPRECGDFAQLVRKIPSLGMCFCEENKEEGKWELVNPPVKTLTHGANAAFNWRNWISGN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BGG7-1", "uniprot_id": "UBS3B_MOUSE", "id": "Q8BGG7-1", "name": "Ubiquitin-associated and SH3 domain-containing protein B", "aln": "----------------------MAAREELYSKVTPRRDRLQRPGTVKHGSALDVLLSMGFPRARAQKALASTGGRSVQAACDWLFSHVGDPFLDDPLPREYVLYLRPTGPLAQKLSDFWQQSKQICGKNKAHNIFPHITLCQFFMCEDSKVDALGEALQTTVSRWKCKFSAPLPLELYTSSNFIGLFVKEDSAEVLKKFAADFAAEAA--SKTE--------------------------------------VHVEPHKKQLHVTLAYHFQASHLPTLEKLAQNIDVKLGCDWVATIFSRDIRFANHETLQVIYPYSPQNDDELELVPGDFIFMSPMEQTSTSEGWIYGTSLTTGCSGLLPENYITKADECSTWIFHGSYSILNTVSSSSL----------------------------AFGDGALERRQYEDQGLGETTPLTIICQPMQPLRVNSQPGPQ---------------------------------------------------------------KRCLFVCRHGERMDVVFGKYWLSQCFDAKGRYIRTNLNMPHSLPQRSGGFRDYEKDAPITVFGCMQARLVGEALLESNTVIDHVYCSPSLRCVQTAHNILKGLQQDNHLKIRVEPGLFEWTKWVAGSTLPAWIPPSELAAANLSVDTTYRPHIPVSKLAI--SESYDTYINRSFQVTKEIISECKSKGNNILIVAHASSLEACTCQLQGLSPQNSKDFVQMVRKIPYLGFCSCEELGETGIWQLTDPPILPLTHGPTGGFNWRETLLQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TF42-1", "uniprot_id": "UBS3B_HUMAN", "id": "Q8TF42-1", "name": "Ubiquitin-associated and SH3 domain-containing protein B", "aln": "-----------MAQYGHPSPLGMAAREELYSKVTPRRNRQQRPGTIKHGSALDVLLSMGFPRARAQKALASTGGRSVQAACDWLFSHVGDPFLDDPLPREYVLYLRPTGPLAQKLSDFWQQSKQICGKNKAHNIFPHITLCQFFMCEDSKVDALGEALQTTVSRWKCKFSAPLPLELYTSSNFIGLFVKEDSAEVLKKFAADFAAEAA--SKTE--------------------------------------VHVEPHKKQLHVTLAYHFQASHLPTLEKLAQNIDVKLGCDWVATIFSRDIRFANHETLQVIYPYTPQNDDELELVPGDFIFMSPMEQTSTSEGWIYGTSLTTGCSGLLPENYITKADECSTWIFHGSYSILNTSSSNSL----------------------------TFGDGVLERRPYEDQGLGETTPLTIICQPMQPLRVNSQPGPQ---------------------------------------------------------------KRCLFVCRHGERMDVVFGKYWLSQCFDAKGRYIRTNLNMPHSLPQRSGGFRDYEKDAPITVFGCMQARLVGEALLESNTIIDHVYCSPSLRCVQTAHNILKGLQQENHLKIRVEPGLFEWTKWVAGSTLPAWIPPSELAAANLSVDTTYRPHIPISKLVV--SESYDTYISRSFQVTKEIISECKSKGNNILIVAHASSLEACTCQLQGLSPQNSKDFVQMVRKIPYLGFCSCEELGETGIWQLTDPPILPLTHGPTGGFNWRETLLQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5YC04-1", "uniprot_id": "A0A8I5YC04_RAT", "id": "A0A8I5YC04-1", "name": "", "aln": "------------------------MGFSLPSKFTPLFQR--------------------------QKALASTGGRSVQAACDWLFSHVGDPFLDDPLPREYVLYLRPTGPLAQKLSDFWQQSKQICGKNKAHNIFPHITLCQFFMCEDSKVDALGEALQTTVSRWRCKFSAPLPLELYTSSNFIGLFVKEDSAEVLKKFAADFAAEAA--SKTE--------------------------------------VHVEPHKKQLHVTLAYHFQASHLPTLEKLAQNIDVKLGCDWVATIFSRDIRFANHETLQVIYPYSPQNDDELELVPGDFIFMSPMEQTSTSEGWIYGTSLTTGCSGLLPENYITKADECSTWIFHGSCSILNTVSSSAL----------------------------AFGDGALERRQYEDQGLGETTPLTIICQPMQPLRVNSQPGPQ---------------------------------------------------------------KRCLFVCRHGERMDVVFGKYWLSQCFDAKGRYIRTNLNMPHSLPQRSGSFRDYEKDAPITVFGCMQARLVGEALLESNTVIDHVYCSPSLRCVQTAHNILKGLQQDNHLKIRVEPGLFEWTKWVAGSTLPAWMPPSELAAANLSVDTTYRPHIPVSKLVI--SESYDTYINRSFQVTKEIISECKSKGNNILIVAHASSLEACTCQLQGLSPQNSKDFVQMVRKIPYLGFCSCEELGETGIWQLTDPPILPLTHGPTGGFNWRETLLQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VCE9-1", "uniprot_id": "EPP_DROME", "id": "Q9VCE9-1", "name": "Ecdysteroid-phosphate phosphatase", "aln": "------------------MATLPPRKSQTPTRICISKQHLTP---------LQTLLQMGFPRHRAEKALASTGNRGVQIASDWLLAHVNDGTLDECAPREYIIYACPTGPFLQQLEEFWAKSRQMCGWNGAHNYVPHITLVSFFKAPDECSLQLSKALKQVVDMTGALLDRPLKLEPYMSQNFMGFFVAEEDANYLKRLALQYVKEVSNSIISDTYEQLDAIVACFPWCG-------AVSSGTRCIPRSSRSISLEPHVKSLHLTLAYQFPQAQFNALKALVETLDASCASNWELRLYSRDPRLATKQVQKVVYPHNPHETDELELRIGDYIYLNTEVVDSSSDGWAEGISWLTGSTGHLPVNYTERTAESDAWTLHRVVQLSKSVASSLTSAEDLDIVDGRSISTEPDDRQNTAHPDIIEGSSFEESEQSVEKYLRQTLKPCLELPSVQLLNSHNLTHQHNPNTPTIEITTNMSSSSTSMSKQPVDEILVEPPAAQPPRPDDTLSVHSDHSLHPGSLDASHAKNRKIYIMRHGERVDFTFG-TWIPYCFDEFGNYMRKDLNMPKTLPRRKNSPEGWQNDSPLTNVGVYQANLIGQALLEAQVQIDHVYCSPSYRCIQTCTSALEGLKLTGKQKIKLEPGLFEWMAWYP-SGVPDWLTKNELTEAKFDVDLDYEPVQPASELTARLKESTEQFYERNHDVILQLL---EQTTGNILVVAHATTLDTCSRQLTGGVPRSTNELRQVIHKIPYCSLATVEQ--VDGVWKLVEPECLPVTHSKNPRFEWNALSAT-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12415-1", "uniprot_id": "TFC7_YEAST", "id": "Q12415-1", "name": "Transcription factor tau 55 kDa subunit", "aln": "----------------------------------------------------------------------------MVVNTIYIARHG------------YRSNWLPEGPYPDPLTGIDSDVP-----LAEHGVQQAKELAHYLLSLDNQPEAAFASPFYRCLETVQPIAKLLEIPVYLERGIGEWYRPDR--------KPVIPVPAG---------------------------------------------------------------------YEILSKFFPGVISQEWDSTLTPNEKGETEQEMYMRFKKFWPLFIERVEKEYPNVECILLVTHAAS--KIALGMSLLGYDNPRMSLNENGDKIRSGSCSLDKYEILKKS-------------------------------------------YDTIDETDDQTSFTYIPFSDRKWVLTMNG---------------------------------------------------------------------NTEFLSSGEEMN------WNFDCVAEAG--SDADIKKRQMTKKTSSPIPEADDQTEVETVYISVDIPSGNYKERTEIAKSAILQYSGLETDAPLFRIGNRLYEG---------------------------SWERLVGTELAFPNAAHVHKKTAGLLS-------PTEENETTNAGQSKGSSTANDPNIQIQEEDVGLPDSTNTSRDHTGDKEEVQSEKIYRIKER---------------IVLSNVRPM-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * * * ** : * : . * * :: . *. : : : : : . . : .. : * . : :* : ..: . : . . * :.: : : : * * :. * ...: . : : . : : . **.:: * * * ::: : . :.:. : *: : : .. . . : * . ..* :.: . . . * .. : : . * .: . . : : :* :. . .: ", "identical_positions": 26, "similar_positions": 97, "identity": "3.28%" }, { "cls_id": "homologset.agr.SGD:S000005637", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1PJK7-1", "uniprot_id": "A0A8M1PJK7_DANRE", "id": "A0A8M1PJK7-1", "name": "", "aln": "------MPLNPVISKLSGKLVVLASASPRRLEILSNAG--LRFEVVPSWFKETLDKSLFKH-PCEYAVETAKQKALEVAQRMPFK-------------------------------------HLKTPDIVIGADTVVT-VDGLILEKPTDKQDAYRMLSRLSGKEHS---VFTGVAIVICRDKNSSVTDYKVVDFYEETKVKFA-ELSEEMLWEYINSGEPMDKAGGYGIQALGG-MLVEYVRGDFLNVVGFPLNHFCKQLGSIFNSP-PASPAHKIKRD----CDEAWTLVNKTTNGDVELLENVKDDSLTSVQEQNVMGLEFAKCNRQ-----DVPHSIISLLDGFKVSKTLFTASKLKVFDVLNTPGGLTLEEVAGQINASLLGTERLLEAAVSLGLLERVRQEEISVYRNTEQASRFLVTDSPVSLHGYILHCNDMVWPLFSHLESAVREGTSQHERAFGKKKEDVFQDVYYSKDEVKIRFMDAMHSIARVTGKDLATAFDLSCYKTACDIGGCTGAMAYEFTKAHPELSVTIFDLPQVIEMRRHFQPK-ENDERVSFVAGDFFKDDLPKADLYILARVLHDWSDEKLHVLLSKLSKMWTPGCGLLVSEILLDEERRRPSRALLQALSM---TEGKQRSTAEYSALLDKHGFTLKHVKHTDNLLDAMLFVKEEQNDKRTLLGCSSASIETAELE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O95671-1", "uniprot_id": "ASML_HUMAN", "id": "O95671-1", "name": "Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein", "aln": "------MVLCPVIGKLLHKRVVLASASPRRQEILSNAG--LRFEVVPSKFKEKLDKASFAT-PYGYAMETAKQKALEVANRLYQK-------------------------------------DLRAPDVVIGADTIVT-VGGLILEKPVDKQDAYRMLSRLSGREHS---VFTGVAIVHCSSKD-HQLDTRVSEFYEETKVKFS-ELSEELLWEYVHSGEPMDKAGGYGIQALGG-MLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSDVEGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKGLLTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQG----YSNTETANVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQSPETRLRFMRAMHGMTKLTACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTVFDLPDIIELAAHFQPPGPQAVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLSRVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFHQVQVVHLGGVLDAILATKVAP--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AKB0-1", "uniprot_id": "A0A8I6AKB0_RAT", "id": "A0A8I6AKB0-1", "name": "", "aln": "------MALKPLAPLLRGYHVVLASASPRRREILDLAG--VVFDVIPSHFSEVPPPEHLLR-PQDLVIANAKGKALDVGMRLSQVREAPVESRLGFCEDDGGVSGCSVLRVGLLVRWRSFLADPETQHLIIGADTIVA-MEGQIMGKPCDREDALRMLTRLNGREHS---VITGVAIILTGGAG-TRDAEVVVVFHEETLVTFS-KLSDELVQEHVEGGEPWDKAGGYGLQARGGAIMAEAVRGDPLNAAGLPLNRLCRELGRRLLPSGPGQEVESQT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86BM0-1", "uniprot_id": "Q86BM0_DROME", "id": "Q86BM0-1", "name": "", "aln": "-------MLAPIKHLLGNYRIVLASGSPRRQELVKMLG--LNAELCPSTFEENLNLEDFKE-FSDYIEATALGKAEEVYSRLRST-------------------------------------GDSKNLIVIAADTMVT-LGKEIYGKPKDPADAIRMLTNLSGTSNR---VFTGVVLKHANGIR---------KFTDTADVYFG-DLLPEQIQSYVDSGDPLDKAGAYGVQGPAG-ALIHRIDGDFYCVMGLPLHRLCCELNKLFLEDLSS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99210-1", "uniprot_id": "NTPPA_YEAST", "id": "Q99210-1", "name": "dTTP/UTP pyrophosphatase", "aln": "MSGNSQLPPDVIGFICSKYDIILASTSPRRYEILHDIMGITDLKTMVSTFEENLDKMNYSTDPIGYVCDTSWHKAQNIIEILTDYEDENPN-------------------------------EIDKPKLIICADTIIIDKSGRIYEKPKTKEVQKKFLMKFCYEDDEPVNVVTAVTLIKWYGRE----NFELVPFRDETKVYFDNKIPLRILEEYVESGDGLEVGGGFKIQGQGA-ILIEKIEGDYYNVVGLPLNKTFKGLYAEANSI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::*** **** *:: . * *.* .: ** :: : ::* ***:: * ** ::* .: .. *.*.*.: . * : : * * .: . : .::..*: : .*.: :*. .. : . : ** . *:**:: * ", "identical_positions": 36, "similar_positions": 54, "identity": "5.16%" }, { "cls_id": "homologset.agr.SGD:S000005638", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQC5-1", "uniprot_id": "SCYL1_MOUSE", "id": "Q9EQC5-1", "name": "N-terminal kinase-like protein", "aln": "MW-FFARDPVRDFPFELSPEPPEGGPPGPWILHRGRKKATGSAVSIFVYDVKPGAEEQTQVAKAAFKRLKTLRHPNILAYIDGLETEK-CLHIVTEAVTPLGTYLKARAEAGGLKEQELSWGLHQIVKALSFLVNDCNLIHNNVCMAAVFVDRAGEWKLGGLDYMYSAQGNGGGPPSKGIPELEQYDPPELADSSSRAVREKWSADMWRLGCLIWEVFNGSLPRAAALRNPGKIPKSLVTHYCELVGANPKVRPNPARFLQNCRAPGGFMSNRFVETNLFLEEIQIKEPAEKQKFFQELSKSLDSFP-EDFCRHKVLPQLLTAFEFGNAGAVVLTPLFKVG-----------KSLRAEEYQEKIIPVVVKMFSSTDRAMRIRLLQQMEQFIQYLDEPTVNTQIFPHVTHGFLDTNPAIREQTVKSMLLLAPKLNEANLNVELMKHFARLQAKDDQGPIRCNTTVCLGKIGSYLSAST--RHRVLTSAFSRATKDPFAPSRVAGVLGFAATHNLYSMDDCAHKILPVLCGLTVDPEKSVRDQAFKTIRSFLSKLESVSEDPTQLAEVEKDVHAASSPGTGGAAASWAGWAVTGVSS--LTSKLIRAHPTPVPSDTTVPQRPVPEGNPAPAPALAQAIPATSGHWETQE-DKDTAEDSATADRWDDEDWGSLE--QEAESVLAQQDDWSAKGQGSRAGQINH-PDHKS---LESHWSSWEVEGSWDQGWQ--------EPSSVEPP-----PEGTRLASEYNWGGAEPSDKGDPFAALS-----------VRPSAQP----------------------------RPDPDSWGEDNWEGLEAESR------QVKAELARKKREE----RRREMEAKRAEKKTTKGPMKLGARKLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M9F8-1", "uniprot_id": "SCYL1_RAT", "id": "Q5M9F8-1", "name": "N-terminal kinase-like protein", "aln": "MW-FFARDPVRDFPFELNPEPPEGGPPGPWVLHRGRKKATGSAVSIFVYDVKPGAEEQTQVAKAAFKRLKTLRHPNILAYIDGLETEK-CLHIVTEAVTPLGTYLKARAEAGGLKEQELSWGLHQIVKALSFLVNDCNLIHNNVCMAAVFVDKAGEWKLGGLDYMYSAQGNGGGPPNKGIPELEQYDPPELADSSSRAVKEKWSADMWRLGCLIWEVFNGSLPRATALRNPGKIPKSLVTHYCELVGANPKVRPNPARFLQNCRAPGGFMSNRFVETNLFLEEIQIKEPAEKQKFFQELSKSLDSFP-EDFCRHKVLPQLLTAFEFGNAGAVVLTPLFKVG-----------KFLSAEEYQQKIIPVVVKMFSSTDRAMRVRLLQQMEQFIQYLDEPTVNTQIFPHVTHGFLDTNPAIREQTVKSMLLLAPKLSETNLNVELLKHFARLQAKDDQGPIRCNTTVCLGKIGSYLSAST--RHRVLTSAFSRATKDPFAPSRVAGVLGFAATHNLYSMDDCAHKILPVLCGLTVDPEKSVRDQAFKTIRSFLSKLESVSEDPTQLAEIEKDVHAASSPGTGGAAASWAGWAVTGVSS--LTSKLIRTHPTPVPSEAAVPQRPVPEGDPAPAPAPASATPATSGHRETQEEDKDAAEDSATADRWDDEDWGSLE--QEAESVLAQQDDWSTKGQGNRAGQVSH-SDHKS---LDSHWSSWEVEGSWDQGWQ--------EPSSVEPP-----PEGTRLASEYNWGGAEPSDKGDPFAALS-----------VRPSTQP----------------------------RPDPDSWGEDNWEGLEAESR------QVKAELARKKREE----RRREMEAKRAEKKATKGPMKLGARKLD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96KG9-1", "uniprot_id": "SCYL1_HUMAN", "id": "Q96KG9-1", "name": "N-terminal kinase-like protein", "aln": "MW-FFARDPVRDFPFELIPEPPEGGLPGPWALHRGRKKATGSPVSIFVYDVKPGAEEQTQVAKAAFKRFKTLRHPNILAYIDGLETEK-CLHVVTEAVTPLGIYLKARVEAGGLKELEISWGLHQIVKALSFLVNDCSLIHNNVCMAAVFVDRAGEWKLGGLDYMYSAQGNGGGPPRKGIPELEQYDPPELADSSGRVVREKWSADMWRLGCLIWEVFNGPLPRAAALRNPGKIPKTLVPHYCELVGANPKVRPNPARFLQNCRAPGGFMSNRFVETNLFLEEIQIKEPAEKQKFFQELSKSLDAFP-EDFCRHKVLPQLLTAFEFGNAGAVVLTPLFKVG-----------KFLSAEEYQQKIIPVVVKMFSSTDRAMRIRLLQQMEQFIQYLDEPTVNTQIFPHVVHGFLDTNPAIREQTVKSMLLLAPKLNEANLNVELMKHFARLQAKDEQGPIRCNTTVCLGKIGSYLSAST--RHRVLTSAFSRATRDPFAPSRVAGVLGFAATHNLYSMNDCAQKILPVLCGLTVDPEKSVRDQAFKAIRSFLSKLESVSEDPTQLEEVEKDVHAASSPGMGGAAASWAGWAVTGVSS--LTSKLIRSHPTTAPTETNIPQRPTPEGVPAPAPTPVPATPTTSGHWETQEEDKDTAEDSSTADRWDDEDWGSLE--QEAESVLAQQDDWSTGGQVSRASQVSN-SDHKSSKSPESDWSSWEAEGSWEQGWQ--------EPSSQEPP-----PDGTRLASEYNWGGPESSDKGDPFATLS-----------ARPSTQP----------------------------RPD--SWGEDNWEGLETDSR------QVKAELARKKREE----RRREMEAKRAERKVAKGPMKLGARKLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VAH7-1", "uniprot_id": "Q9VAH7_DROME", "id": "Q9VAH7-1", "name": "N-terminal kinase-like protein", "aln": "MWSFFSRDSSKDFPYDIGEPVGGFDQYSIWTLHKAKRKTTLEEVSVFVYDIRSGSDTKCELAKAALKRLKTLRHPSILQYLDSLETDK-MLYVATEAVDPLGTYFSKLGSDNVQKGLYLAWGIFQITRALSFLNNDGNLRHNNVSAWSVFVNASGEWKLGSLEYVSAADGNP-MPPAKIPVTLEVYDSPEKNDPSKLKAATKCSVDMWGLGCLVWEAFNGVLKQRSNLKDIEHIPKSLQSLYCELVGASPSNRPNPADIITRCRKPGGFFKNDLVDTLLFLEEIQIKDKAEKNRFFSGLTTHLDNFP-DNVCRHKILPQLITAYEYGDAGSAVLAPMFKLG-----------KLLDEVEYQKRIVPCVVKLFASTDRVTRSRLLQQLDLFIAHLQPQVVNDQIFPQVAHGFLDTNATIREQTVKSIIHLAPKLNYNNLNVEVLRHFARLQARDDQGGIRTNTTVCLGKIAPHLHPQV--RQRVLVSAFIRAMRDPFPPARVAGVLALAATQQYFLLSEVANRVLPSLCSLTVDPEKTVRDPAFKTIRGFLGKLEKVSEDPSLRETMEADVHTAT-PSIGNAAATWAGWAVTAVTAKFYRSQSDSSRPRPPLTGRNLSKPASLEQPSSSSLSTTTSSVTSMTSLEHESNDTSASASDYGNNDWDNENWGEMDTSQDPSSPLAASSNNGALMAANALSEVRDGWDNEEWGSLEEDPCEEEEQAEQEQQQQQLARQSISSTSSSQPNQRPLLPHQQQYPHQQQLQQHELNDLIEPLAKLNSHVTSPSKQSMLRPKELPNLSSSNTSPTSATANCNNISPPSSHLNNSTHNANWNSDSWADGEFEPLDESGFGNAKLDEARRKREEKKLQRQRELEARRAQR--ASGPMKLGAKKL-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D3ZK09-1", "uniprot_id": "D3ZK09_RAT", "id": "D3ZK09-1", "name": "", "aln": "----MGSENSALKSYTLGEPP--YTLPSGLAVYPAVLQD-GKCASVFVYKR-----ENEDKVNKAAKHLKTLRHPCLLRFLSCTVEAD-GIHLVTERVQPLEVALETLSP------AEVCAGIYDILLALVFLHERGHLTHNNVCLSSVFVSEDGHWKLGGMETVCKVSQATPEFLRSIQSVRDPASIPPEEMSPDFAALPESHGHAR-DAYAFGALVDSLLPIFNEQVSADVLSSFLQTLHSALLSPTPTCRPALSTLLS-----HDFFRNDFLEVVNFLKSLTLKSEDEKTEFFKFLLDRVSCLS-EELIASRLVPLLLNQLVFAEPVAVKSFLPYLLGPKKENAPGETPCLLSPALFQSRVIPVLLQLFEVHEEHVRMVLLSHIEAYVEHFTQEQLKKVILPQVLLGLRDTSDSIVAITLRSLAVLVSLLGP-----EVVVGGQRSKIFKRTAPSFTKTSDLSPEGSPMHVVCS--QQSRISKVLENPSSNVFPK-WFSGNMSINSRK--HIQEEYYSTLLQT-------------------------DVKNTSED------------NGSFPAGSNKPEEWPDWSEP-----------------EEPEHQTTSIHIWPQEPGDVAETQHTSLSAQELSWDDCESS-FGPEVNTAARASAPRPVTSGE--QMPTAALLPLTEESKPVQSRPSSKTSHRQQ---------EEVKAPQMS-QERPPQ--------------------VRSELGLGEEFTIQVKKKPAQDPELDWFAD----------MVPEIKP----------------------------SGTFLILPELRTEGMVPDKD------TVSPVMQFSSKFA-----ATEMTEGEAEGWEGE-ELAWEDDNW-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IZE3-1", "uniprot_id": "PACE1_HUMAN", "id": "Q8IZE3-1", "name": "Protein-associating with the carboxyl-terminal domain of ezrin", "aln": "----MGSENSALKSYTLREPP--FTLPSGLAVYPAVLQD-GKFASVFVYKR-----ENEDKVNKAAKHLKTLRHPCLLRFLSCTVEAD-GIHLVTERVQPLEVALETLSS------AEVCAGIYDILLALIFLHDRGHLTHNNVCLSSVFVSEDGHWKLGGMETVCKVSQATPEFLRSIQSIRDPASIPPEEMSPEFTTLPECHGHAR-DAFSFGTLVESLLTILNEQVSADVLSSFQQTLHSTLLNPIPKCRPALCTLLS-----HDFFRNDFLEVVNFLKSLTLKSEEEKTEFFKFLLDRVSCLS-EELIASRLVPLLLNQLVFAEPVAVKSFLPYLLGPKKDHAQGETPCLLSPALFQSRVIPVLLQLFEVHEEHVRMVLLSHIEAYVEHFTQEQLKKVILPQVLLGLRDTSDSIVAITLHSLAVLVSLLGP-----EVVVGGERTKIFKRTAPSFTKNTDLSLEDSPMCVVCS--HHSQISPILENPFSSIFPKCFFSGSTPINSKK--HIQRDYYNTLLQTGDPFSQ---------PIKFPINGLSDVKNTSED------------SENFPSSSKKSEEWPDWSEP-----------------EEPENQTVNIQIWPREPCDDVKSQCTTLDVEESSWDDCEPSSLDTKVNPGGGITATKPVTSGE--QKPIPALLSLTEESMPWKSSLPQKISLVQRGDD-----ADQIEPPKVSSQERPLK--------------------VPSELGLGEEFTIQVKKKPVKDPEMDWFAD----------MIPEIKP----------------------------SAAFLILPELRTE-MVPKKD------DVSPVMQFSSKFA-----AAEITEGEAEGWEEEGELNWEDNNW-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12453-1", "uniprot_id": "CEX1_YEAST", "id": "Q12453-1", "name": "Cytoplasmic export protein 1", "aln": "MNFSSIFKSISNFQFPYTIEETAITETALWQCFDGTRKADSLPVTVFKAKRSP---ENESLILNAVHKSKILKIPGLCTVLETFDSDPQSTFIVTERVVPFPWDNLGSLSQN---KFGVELGISQLLATLGFLKN---FVLGTLSKDSVFINIKGEWVLFGLELCSSKEGLSAFEFAS------RARSYYNIIGSQLPCEDPNTIDSMGLGLLIKSLMAPSCLPKDWIVNVNMISDGKITIENFRKRLENTETWRSNPLINFYQELRELHIKDPQGKLVVMSNLENLYLESREIFRNLTPGMIENFIIPELCEIIKLLMTQSISSAASPIGMNFNASHKLVP---FLAIVLDLTSETNTFPVGFNDLITQSFKLPDRQVRFLLLIYLPKLIGPLSKSEISSRIYPHFIQGLTDSDATLRLQTLKTIPCIVSCLTERQLNNELLRFLAKTQVDSD-VEIRTWTVIIISKISTILSTSVGNRSNILATAFTKSLKDPQVKPRLAALYGLEKSIELFDVNTIANKILTVIAPGLLDKSPIVRGRAKILFEEYLEKLEKEAQLIQTN--------DSTADSEDVKDIDFENYGCDE---------------EDMNKEDNLLAAQFLNNLRLNSPSATTPSNITESEIDSAQDGSGWDDLSDTDGFITNGTTESFDETTNPVTTASTPKLFGKPIKINKS------------------WNDELNDDGWIQDES----------------------GPSKVPQKHTRPQNSTLAKSIAPSSR------------LSIKKKK----------------------------TTILAPRNIASNSTVTTKSS-------LSNKTARSKPISS--IRGSVTKKGNVDGWDDDGDSDSWDTNW-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . . : .::* . : . * :: * *: * : :. .:.** * *: : *: :: :* ** : : ..:. :**:. *.* * .:: . . . . . . . . :.. . . :: : : .:..: .: * . :. : :. : . ... . . : : . : : * :. * ** : : : :. * *:. *: *:. :: *:::: :.. * *:: : : . . : .. : : : .. . .:. : . :* .::. :: . . . : .:. . : . : . . . . : . . . . : . : . . . . . ..: . : ", "identical_positions": 31, "similar_positions": 163, "identity": "3.47%" }, { "cls_id": "homologset.agr.SGD:S000005639", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1ASA5-1", "uniprot_id": "B1ASA5_MOUSE", "id": "B1ASA5-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRSSPSGKGPSRMAEPRFNNPYFWPPPPTMPSQLDNLVLINKIKEQLMAEKIRPPHLPPTSASSQQPLLVPPAPAESSQAVMSLPKLQQVPGLHPQSVPQPDVALHARPATSTVTGLGLSSRTPAVSTSESTP--GTGTGTSTPSTP-----TTTSQSRLIASSPTLISGITSPPLLDSIKTIQGHGLLGPPKSERG----RKK-IKAENPGGPP---VLVVPYPILASGETAKEGKTYRCKVCPLTFF-TKSEMQIHSK-SHTEAKPHKC--PHCSKSFANASYLAQHLRIHLG--VKPYHCSY--CDKSFRQLSHLQQHT-RIHTGDRPYKCPHPGCEKAFTQLSNLQSHQRQHNKDKP--------------------------------------------------------------YKCPNCYR---AYSDSASLQIHLSAHAIK-HAKAYCCSMCGRAYTSETYLMKHMS--------------------------KHTVVEHLVSHHSPQRTESPGIPVRISLI-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZWA1-1", "uniprot_id": "A0A8I5ZWA1_RAT", "id": "A0A8I5ZWA1-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRSSPSGKGPSRMAEPRFNNPYFWPPPPTMPSQLDNLVLINKIKEQLMAEKIRPPHLPPTSASSQQPLLVPPAPAESSQAVMSLPKLQQVPGLHPQSVPQPDVALHARPATSTVTGLGLSSRTPAVSTSESTP--GTGTGTSTPSTP-----TTTSQSRLIASSPTLISGITSPPLLDSIKTIQGHGLLGPPKSERG----RKK-IKAENPGGPP---VLVVPYPILASGETAKEGKTYRCKVCPLTFF-TKSEMQIHSK-SHTEAKPHKC--PHCSKSFANASYLAQHLRIHLG--VKPYHCSY--CDKSFRQLSHLQQHT-RIHTGDRPYKCPHPGCEKAFTQLSNLQSHQRQHNKDKP--------------------------------------------------------------YKCPNCYR---AYSDSASLQIHLSAHAIK-HAKAYCCSMCGRAYTSETYLMKHMS--------------------------KHTVVEHLVSHHSPQRTESPGIPVRISLI-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5T0B9-1", "uniprot_id": "ZN362_HUMAN", "id": "Q5T0B9-1", "name": "Zinc finger protein 362", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRSSPSGKGHSRMAEPRFNNPYFWPPPPTMPSQLDNLVLINKIKEQLMAEKIRPPHLPPTSASSQQPLLVPPAPAESSQAVMSLPKLQQVPGLHPQAVPQPDVALHARPATSTVTGLGLSTRTPSVSTSESSAGAGTGTGTSTPSTP-----TTTSQSRLIASSPTLISGITSPPLLDSIKTIQGHGLLGPPKSERG----RKK-IKAENPGGPP---VLVVPYPILASGETAKEGKTYRCKVCPLTFF-TKSEMQIHSK-SHTEAKPHKC--PHCSKSFANASYLAQHLRIHLG--VKPYHCSY--CDKSFRQLSHLQQHT-RIHTGDRPYKCPHPGCEKAFTQLSNLQSHQRQHNKDKP--------------------------------------------------------------YKCPNCYR---AYSDSASLQIHLSAHAIK-HAKAYCCSMCGRAYTSETYLMKHMS--------------------------KHTVVEHLVSHHSPQRTESPGIPVRISLI-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D0B1-1", "uniprot_id": "ZN524_MOUSE", "id": "Q9D0B1-1", "name": "Zinc finger protein 524", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDNPSSDPLPSTLSGEEE-----------------------------KPLALLPPVPR------------------------------------------GRRGRPP--------------GGATTSNRT-----LKSSLPRKRGRPP---------------RSEQETPLTAPVDSGGS----SDL-LLIDDQGVPY---TVPEGSAADGPQGSGSKRAPHFCPVCLRAFP-YLSDLERHSI-SHSELKPHVC--KDCGKTFKRSSHLRRHCNIHAG--LRPFRCVL--CPRRFREAGELAHHH-RIHSGERPYQCPS--CRVRFTEANTLRRHYKRKHPELVGMP----------------------------------------------------------VRLCPPNPRTQPLWDDDEGIPVQEGVQEESPEGKEPTWPISSTTSPLSGFTAGGSAGAGRG------------------QEGQDTLVSGGIPTMEGDQKQGP-KPLGPGAIGHPPVD-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41696-1", "uniprot_id": "AZF1_YEAST", "id": "P41696-1", "name": "Transcription factor AZF1", "aln": "MPPPTAQFMGPTQAGQNESQNQSSGEAGEQNQEHGQGPTPILNQSQPASSQPQHQQQRNESISYYTNFNQPRYSTDASINSFLNISDNVPVTSTGGPSSGGAYSNLPRLSTSSTHQPPDLSQIGRGFSIVNNLFPQQQQLQNQHRQQQQQQQQQSHQQPPFKTPSFSTGLTGSSSQYQFLPRNDNTSQPPSKRNSVYLGPNDGPDFEFFSMQQSQQPQFQPSSRRESNSMRPPLLIPAATTKSQSNGTNNSGNMNTNADYESFFNTGTNNSNSNQNPYFLSSRNNSLKFNPEDFDFQFKRRNSFVRGTLDHSSQNAFIPESRLNSLSVNNKANGDPVADNVTNNMKGKSNEVDNDDGNDSSNNNNNNNNNNNNENNNDNNNDNNDNSINSATSTNIPNQEDHSLASTDTTSNSRKDLKEIEQRLRKHLNDEDNYSSAISRPLDKNDVIEGSEGLNKHIDESGMQPNIIKKRKKDDSTVYVKNEMPRTDPPMSKDNSTSAEGAAMANFSGKEP-----PIPDISSVSDDATNLIGATKVDQLMLIIQARK-KGFTEKVNTTQD----GDL-LFNQTMDILPPKSELVGGVEKPKGTQNTRAVKKHECPYCHRLFS-QATHLEVHVR-SHIGYKPFVC--DYCGKRFTQGGNLRTHERLHTG--EKPYSCDI--CDKKFSRKGNLAAHL-VTHQKLKPFVCKLENCNKTFTQLGNMKAHQNRFHKETLNALTAKLAEMNPSENIPLEERQLLEYFASIYKNSNRGIKGRGKGVGTKKSTISSPENHPASTILNPNTNANNAIANDSENNGNPEGNIDSSSNSNPGSHSMISPTQKDMGTLQSQFIQNNFNNSVNSSNPSNQPIINYNYTTLPHSRLGSSSSSNTNNNNSNFSVGAAPGVLMAPTTNNDFSFNLDQSNDNERSQQEQVRFKNINYKS-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8BKX7-1", "uniprot_id": "ZN410_MOUSE", "id": "Q8BKX7-1", "name": "Zinc finger protein 410", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLSDELESKPELLVQFVQNTSIPLGQGLVESEAKDITCLSLLPVTEASECSRLMLPDETPNHANSSKEVPSSAVLRSLQVNVGPDGEETRAQTVQKSPEFLTTPESPSLLQDLQPSDSTSFILLNLTRAGLGSSAEHFVFVQDET-----EDSGADFLSAESTDS-----SIPWFLRVQELAHDSLIAATRAQLA----KNA-KTGSNGENVHLG-SGDGQPKDSGPLPQAEKKLKCTVEGCDRTFV-WPAHFKYHLK-THRNERSFICPAEGCGKSFYVLQRLKVHMRTHNG--EKPFMCHESGCGKQFTTAGNLKNHR-RIHTGEKPFLCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCG------------------------------------------------------KTFSQSGSRNVHMRKHHLQLGTTGSQEQDQTAEPLMGSSLLEDASVPNKNLVSMNSQSSLGGES---------------LNLSNTNSILGVDDEVLTERASRPLSSVPDVTHHLVTMQSGRQSYEVSVLTAVNPQELLNQGDLTERQT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BU19-1", "uniprot_id": "ZN692_HUMAN", "id": "Q9BU19-1", "name": "Zinc finger protein 692", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASSPAVDVSCRRREKRRQLDARRSKCRIRLGGHMEQWCLLKERLGFSLHSQLAKFLLDRYTSSGCVLCAGPEPLPPK--------------GLQYLVLLSHAHSRECSLVPGLRGPGGQDGGLVWECSAGHTFSWGPSLSPTPSEAPKPASLPHTTRRSWCSEATSGQELADLESEHDERTQEARLPRRVGPPPETFPPPGEEEGEEEEDNDEDEEEMLSDASLWTYSSSPDDSEPDAPRLLPSPVTCTPKEGETPPAPA-----ALSSPLAVPALSASSLSSRAPPPAEVRVQPQLSRTPQAAQQTEAL----ASTGSQAQSAPTPAWDEDTAQIGPKRIRKAAKRELMPCDFPGCGRIFS-NRQYLNHHKKYQHIHQKSFSCPEPACGKSFNFKKHLKEHMKLHSD--TRDYICEF--CARSFRTSSNLVIHR-RIHTGEKPLQCEI--CGFTCRQKASLNWHQRKHAETVAALR----------------------------------------------------------------------FPCEFCGKRFEKPDSVAAHRSKSHPALLLAPQESPSGPLEPCPS------------------------------ISAPGPLGSSEGSRPSASPQAPTLLPQQ----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I7HJS4-1", "uniprot_id": "ZN683_MOUSE", "id": "I7HJS4-1", "name": "Tissue-resident T-cell transcription regulator protein ZNF683", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKALDGLRESLYPSLDFQLYQDDQVCSADASQPLADSVGAHDLAWSERMCPLPLAPAKSPLLACPESPDLCLCALQKTPLGRAPQDLGEDASNMRHQPPSLYKASTDSEKLTIKDSLNREEMGNEPERGAYPHLPPRTSSFPDAGLDRKSLSPLTFWPWLPPTLISKEPPIHIYPIFPGYPLLPLPYLFTYGALPSAQHPYLFMLPPHSTYPTVAGPSLLMTASGSGPR-IPQEKTLLLHSGAFQSAGHTLHSQVESRSSRDTRTPGQAGVAAPTRRAVPGSRAGVIALPYPLKKENGKILYECNVCGKNFGQLSNLKVHLRVHSG--ERPFQCAL--CQKRFTQLAHLQKHH-LVHTGERPHQCQV--CHKRFSSSSNLKTHLRLHSGAKPSQCG-----------------------------------------------------------LCPSYLTPNVYPKLHHRLRAPQLRGLTHTHLPLASLTCLAQWHQGALDLVEKKMG-------------------------------WTVDKVSSESKGKQG---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56270-1", "uniprot_id": "MAZ_HUMAN", "id": "P56270-1", "name": "Myc-associated zinc finger protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFPVFPCTLLAPPFPVLG----------------LDSRGVGGLMNSFPPPQGHAQNPLQVGAELQSRFFASQGCAQSPFQAAPAPPPTPQAPAAEPLQVDLLPVLAAAQESAAAAAAAAAAAAAVAAAPPAPAAASTVDTAALKQPPAPPPPPPPVSAPAAEAAPPASAATIAAAAATAVVAPTSTVAVAPVASALEKKTKSKGP--YICALCAKEFKNGYNLRRHEAIHTGAKAGRVPSGAMKMPTMVPLSLLSVPQLSGAGGGGGEAGAGGGAAAVAAGGVVTTTASGKRIRKNHACEMCGKAFR-DVYHLNRHKL-SHSDEKPYQC--PVCQQRFKRKDRMSYHVRSHDGAVHKPYNCSH--CGKSFSRPDHLNSHVRQVHSTERPFKCEK--CEAAFATKDRLRAHTVRHEEKVPCHVCG--------------------------------------------------------------KMLSSAYISDHMKVHSQGPHHVCELCNKGTGEVCPMAAAAAAAAAAAAAA-------------------------------VAAPPTAVGSLSGAEGVPVSSQPLPSQPW--------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . : * : * : * . * . : : * * : * .* * * :* * * :. * ", "identical_positions": 14, "similar_positions": 17, "identity": "1.5%" }, { "cls_id": "homologset.agr.SGD:S000005641", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZES2-1", "uniprot_id": "D3ZES2_RAT", "id": "D3ZES2-1", "name": "Trafficking protein particle complex subunit 6B", "aln": "--------------------------------------MADEALFLLLHNEMVSGVYK-SAEQG------------------------------------------------EVENGRCITKLENMGFRVGQGLIERFTKDT-----ARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFR----LLIQLSAGKQYLEHASKYLAFTCGLIRGGLSNLGIKS---IVTAEVSSMPACKFQVMIQKL-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D289-1", "uniprot_id": "TPC6B_MOUSE", "id": "Q9D289-1", "name": "Trafficking protein particle complex subunit 6B", "aln": "--------------------------------------MADEALFLLLHNEMVSGVYK-SAEQG------------------------------------------------EVENGRCVTKLESMGFRVGQGLIERFTKDT-----ARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFR----LLIQLSAGKQYLEHASKYLAFTCGLIRGGLSNLGIKS---IVTAEVSSMPACKFQVMIQKL-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86SZ2-1", "uniprot_id": "TPC6B_HUMAN", "id": "Q86SZ2-1", "name": "Trafficking protein particle complex subunit 6B", "aln": "--------------------------------------MADEALFLLLHNEMVSGVYK-SAEQG------------------------------------------------EVENGRCITKLENMGFRVGQGLIERFTKDT-----ARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFR----LLTQMSAGKQYLEHASKYLAFTCGLIRGGLSNLGIKS---IVTAEVSSMPACKFQVMIQKL-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QMV3-1", "uniprot_id": "TPC6B_DANRE", "id": "F1QMV3-1", "name": "Trafficking protein particle complex subunit 6b", "aln": "--------------------------------------MADEALFQFLHSEIIQYVN--SAETG------------------------------------------------ESENGRCVSKLENMGFRVGQGLIERFTKDT-----PRFKDELDVMKFICKDFWTSVFKKQIDNLRTNHQGIYVLQDNKFR----LLTQLSAGKQYLEHAPKFLAFTCGLVRGALSNIGVKS---IVTAEVSVMPACKFQVMIQKM-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q78XR0-1", "uniprot_id": "TPC6A_MOUSE", "id": "Q78XR0-1", "name": "Trafficking protein particle complex subunit 6A", "aln": "--------------------------------------MADAVLFEFLHTEMVAELWAPDPDPG------------------------------------------------SGGKRRSLSVLEGLGFRVGQALGERLPLET-----PAFREELDALKFLCRDLWAAMFQKHMDGLRTNHQGTYVLQDNSFP----LLVTMGSGPQYLEEAPKFLAFTCGLLCGALHTLGFQS---LVTASVASLPACKFQVVIQKS-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LBL2-1", "uniprot_id": "A0ABK0LBL2_RAT", "id": "A0ABK0LBL2-1", "name": "Trafficking protein particle complex subunit 6A", "aln": "-----------------------MGGKCWPGARGERWRMADAVLFEFLHTEMVAELWAPDPDPG------------------------------------------------SGGKKKSLSVLEGLGFRVGQALGERLPRET-----LAVREELDALKFLCKDLWAAMFQKHMDGLRTNHQGTYVLQDNSFP----LLIPMGSGPQYLEEAPKFLAFTCGLLCGALHTLGFQS---LVTASVASLPACKFQVVIQKS-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75865-1", "uniprot_id": "TPC6A_HUMAN", "id": "O75865-1", "name": "Trafficking protein particle complex subunit 6A", "aln": "--------------------------------------MADTVLFEFLHTEMVAELWAHDPDPG------------------------------------------------PGGQKMSLSVLEGMGFRVGQALGERLPRET-----LAFREELDVLKFLCKDLWVAVFQKQMDSLRTNHQGTYVLQDNSFP----LLLPMASGLQYLEEAPKFLAFTCGLLRGALYTLGIES---VVTASVAALPVCKFQVVIPKS-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VF82-1", "uniprot_id": "Q9VF82_DROME", "id": "Q9VF82-1", "name": "Trafficking protein particle complex subunit 6B", "aln": "--------------------------------------MSEEILFDCLHAEIVNYCLD-------------------------------------------------------SNKEHDLATLEYIGFTTGYRLIERLTREV-----SRFKDELETMKFICTDFWMLIYKKQVDNLRTNNHGMYVVQDKAFR----FLTRISPGTKQLEHAPKFVAFTCGLVRGALSNLGINS---TVTAEVQSIPACKFHIEVNRN-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99394-1", "uniprot_id": "TRS33_YEAST", "id": "Q99394-1", "name": "Trafficking protein particle complex subunit 33", "aln": "MSSTHSNNVGHPQSSPQGPLTEQQRAQQQYQIFENSLPKVSQSVYQMLLNEMVPLAMGIERQISGDVISSDSNVTSENGNINNMIKRLKIEEHHTVDIIRSHNLIHELYKADEEEKEKVLARLRNIGFQIGLKLSELLIFSNNPNLKFKEMDLLLIMKFICRDVWKQIFGKQIDNLKTNHRGTFYLLDYDYRPIQSFSLEEDAKNEELKMIEPFLEIPVGIIRGVLSSLGYSSEEVICLASFIDRPTDRPKTAFPKGVSFHVQVTMPQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: * *:: : :: *. :** * * * : . : * :**:* *.* :: *::*.*:**::* : : * : : . : *: :: :. *:: * * .:* .* *.. *. : : . : ", "identical_positions": 29, "similar_positions": 47, "identity": "10.82%" }, { "cls_id": "homologset.agr.SGD:S000005642", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PTB6-1", "uniprot_id": "E9PTB6_RAT", "id": "E9PTB6-1", "name": "DNA-directed RNA polymerase subunit", "aln": "MVKEQFRETDVAKKISHICFGMKSPEEMRQQAHIQVVSKNLYSQDNNHAPLLYGVLDHRMGTSEKDRPCETCGKNLADCLGHYGYIDLELPCFHVGYFRAVIGILQMICKTCCHIMLSQEEKQQFLDFLKRPGLTYLQKRGLKKKISDKCRKKSTCHYCGAFNGTVKK------CGLLKIIHEKYKTNKKVVDPIVSNFLQSFETAIEHNKEVEPLLG--RAQENLNPLVVLNLFKRIPAEDVPLLLMNP--EAGKPSDLILTRLLVPPLCIRPSVVSDLKSGTNEDDLTMKLTEIIFLNDVIKKHRISGAKTQMIMEDWDFLQLQCALYINS------ELSGIPLNMAPKKWTRGFVQRLKGKQGRFRGNLSGKRVDFSGRTVISPDPNLRIDEVAVPVHVAKILTFPEKVNKANINFLRKLVRNGPDVHPGANFIQQRHMQMKRFLKYGNREKMAQELKFGDIVERHLIDGDVVLFNRQPSLHKLSIMAHLAKVKPHRTFRFNECVCTPYNADFDGDEMNLHLPQTEEAKAEALVLMGTKANLVTPRNGEPLIAAIQDFLTGAYLLTLKDTFFDRAKACQIIASILVGKDEKIKVRLPPPTILKPVTLWTGKQIFSVILRPSDDNPVRANLRTKGKQYCG-----KGEDLCTNDSYVTIQNSELMCGSMDKGTLGSGSKNNIFYILLRDWGQNEAADAMSRLARLAPVYLSNRGFSIGIGDVTPGQGLLKAKYELLNAGYKKCDEYIEALNTGKLQQQPGCTAEETLEALILKELSVIRDHAGSACLRELDKSNSPLTMALCGSKGSFINISQMIACVGQQAISGSRVPDGFENRSLPHFEKHSKLPAAKGFVANSFYSGLTPTEFFFHTMAGREGLVDTAVKTAETGYMQRRLVKSLEDLCSQYDLTVRSSTGDIIQFIYGGDGLDPAAMEGKDEPLEFKRVLDNIKAVYPCQSERALSKNELTLTTEAIMK----------KNEFLCCQDSFLQ---------------EIKTFIKGVSEKIKKTRDKYGIN-------------DNGTTEPR----VLYQLDRITRTQIEKFLETCRDKYMRAQMEPGSAVGALCAQSIGEPGTQMTLKTFHFAGVASMNITLGVPRIKEIINASKAISTPIITAQLDMDDDADYARLVKGRIEKTLLGEISEYIEEVFLPDDCFILVKLSLERIRLLRLEVNAETVRYSICTS-KLRVKPGDVAVHG--------------EAVVCVTPRENSKSSMYYVLQFLKEDLPKVVVQGIPEVSRAVIHIDEQSGKEKFKLLVEGDNLRAVMATHGVKGTRTTSNNTYEVEKTLGIEAARTTIINEIQYTMVNHGMSIDRRHVMLLSDLMTYKGEVLGITRFGLAKMKESVLMLASFEKTADHLFDAAYFGQKDSVCGVSECIIMGIPMNIGTGLFKLLHKANRDPKPPR-RPLIFDTHEFHIPLVT-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14802-1", "uniprot_id": "RPC1_HUMAN", "id": "O14802-1", "name": "DNA-directed RNA polymerase III subunit RPC1", "aln": "MVKEQFRETDVAKKISHICFGMKSPEEMRQQAHIQVVSKNLYSQDNQHAPLLYGVLDHRMGTSEKDRPCETCGKNLADCLGHYGYIDLELPCFHVGYFRAVIGILQMICKTCCHIMLSQEEKKQFLDYLKRPGLTYLQKRGLKKKISDKCRKKNICHHCGAFNGTVKK------CGLLKIIHEKYKTNKKVVDPIVSNFLQSFETAIEHNKEVEPLLG--RAQENLNPLVVLNLFKRIPAEDVPLLLMNP--EAGKPSDLILTRLLVPPLCIRPSVVSDLKSGTNEDDLTMKLTEIIFLNDVIKKHRISGAKTQMIMEDWDFLQLQCALYINS------ELSGIPLNMAPKKWTRGFVQRLKGKQGRFRGNLSGKRVDFSGRTVISPDPNLRIDEVAVPVHVAKILTFPEKVNKANINFLRKLVQNGPEVHPGANFIQQRHTQMKRFLKYGNREKMAQELKYGDIVERHLIDGDVVLFNRQPSLHKLSIMAHLARVKPHRTFRFNECVCTPYNADFDGDEMNLHLPQTEEAKAEALVLMGTKANLVTPRNGEPLIAAIQDFLTGAYLLTLKDTFFDRAKACQIIASILVGKDEKIKVRLPPPTILKPVTLWTGKQIFSVILRPSDDNPVRANLRTKGKQYCG-----KGEDLCANDSYVTIQNSELMSGSMDKGTLGSGSKNNIFYILLRDWGQNEAADAMSRLARLAPVYLSNRGFSIGIGDVTPGQGLLKAKYELLNAGYKKCDEYIEALNTGKLQQQPGCTAEETLEALILKELSVIRDHAGSACLRELDKSNSPLTMALCGSKGSFINISQMIACVGQQAISGSRVPDGFENRSLPHFEKHSKLPAAKGFVANSFYSGLTPTEFFFHTMAGREGLVDTAVKTAETGYMQRRLVKSLEDLCSQYDLTVRSSTGDIIQFIYGGDGLDPAAMEGKDEPLEFKRVLDNIKAVFPCPSEPALSKNELILTTESIMK----------KSEFLCCQDSFLQ---------------EIKKFIKGVSEKIKKTRDKYGIN-------------DNGTTEPR----VLYQLDRITPTQVEKFLETCRDKYMRAQMEPGSAVGALCAQSIGEPGTQMTLKTFHFAGVASMNITLGVPRIKEIINASKAISTPIITAQLDKDDDADYARLVKGRIEKTLLGEISEYIEEVFLPDDCFILVKLSLERIRLLRLEVNAETVRYSICTS-KLRVKPGDVAVHG--------------EAVVCVTPRENSKSSMYYVLQFLKEDLPKVVVQGIPEVSRAVIHIDEQSGKEKYKLLVEGDNLRAVMATHGVKGTRTTSNNTYEVEKTLGIEAARTTIINEIQYTMVNHGMSIDRRHVMLLSDLMTYKGEVLGITRFGLAKMKESVLMLASFEKTADHLFDAAYFGQKDSVCGVSECIIMGIPMNIGTGLFKLLHKADRDPNPPK-RPLIFDTNEFHIPLVT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PWI3-1", "uniprot_id": "A0A8M9PWI3_DANRE", "id": "A0A8M9PWI3-1", "name": "DNA-directed RNA polymerase subunit", "aln": "MVKEQFRETDVARKISHICFGMKSSEQMRQQAHIQVVSKNLYSQDTSHKPLQYGVLDHRMGTSEKDRPCETCGKNLADCLGHYGYLDLELPCFHIGYFKAIVGILQMICKTCSHILLTKEEKLQFLDYLRRPGLAYLQKRGLKKKISDKCRKKTVCLNCNAFNGSVKK------CGLLKIIHEKYKSTKKVVDPAVSDFLQSFDVAIEHNKEVESLLT--RAQENLNPLVVLNLFRRIPDKDVPLLLMNP--ESGKPADLILTRLLVPPLCIRPSVVSDLKSGTNEDDLTMKLTEIIFLNDVIKKHRMTGAKTQMIMEDWDFLQLQCALYINS------ELSGIPLNMAPKKWTRGFVQRLKGKQGRFRGNLSGKRVDFSGRTVISPDPNLRIDEVAVPVHVAKILTYPEKVNKANIELMRKLVRNGPEVHPGANFIQQRHMQMKRFLKYGNREKMAQELKFGDVVERHMIDGDIVLFNRQPSLHKLSIMAHIARVKPHRTFRFNECVCTPYNADFDGDEMNLHLPQTEEAKAEALVLMGTKANLVTPRNGEPLIAAIQDFLTGAYLLTLKDTFFDRTKACQIVASILVGKDEKIKISLPHPAILKPIRLWTGKQIFSLILKPSKSCPVMANLRTKGKQYCG-----KGEDLCANDSFVVIHNSELMCGSMDKGTLGSGSKNNIFYILLRDWGQQEAADAMSRLARLAPVYLSNRGFSIGIGDVTPGQGLLKAKQELLDAGYEKCDEYIDALKTGRLQQQPGCTAEETLEALILKELSVIRDHAGSACLRELDKSNSPLIMALCGSKGSFINISQMIACVGQQAISGSRVPDGFENRSLPHFQKHSKLPAAKGFVADSFYSGLTPTEFFFHTMAGREGLVDTAVKTAETGYMQRRLVKSLEDLCSQYDLTVRSSTGDIIQFIYGGDGLDPAAMEGKDEPLEFKRVLDNIRAVYSCTGEPALSRNELLLTSDSIMK----------RKDFLCCKDTFLETLTDTGSDKY---MQEIRKFIKTVSEKVKKTRDKYGIN-------------DNGTTEPK----VLYQLDRITPTQLEKFLETCRDKYMRAQMEPGSAVGALCAQSIGEPGTQMTLKTFHFAGVASMNITLGVPRIKEIINASKNISTPIISANLDTNDDPDFARLVKGRIEKTLLGEISEYIEEVFLPDDTFILVKLSLDRIRLLRLEVNAETVRYSICTS-KLRVKPGDVQVHG--------------EAVVCVSPRENSKSSMYYVLQSLKQDLPKVVVQGIPEVSRAVIHIDEQSGKQKFKLLVEGDNMRSVMATHGVNGSKTTSNNTYEVEKTLGIEAARSTIINEIQYTMVNHGMSIDRRHVMLLADLMSYKGEILGITRFGLAKMKESVLMLASFEKTADHLFDAAYFGQKDSVCGVSECIIMGIPMNIGTGLFKLLHRSNREADPPR-RPLLFDSPDFHIPIAL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JUY3-1", "uniprot_id": "A8JUY3_DROME", "id": "A8JUY3-1", "name": "DNA-directed RNA polymerase subunit", "aln": "MPKEQFRASALNKKISHVQFGISGADEIQQEALVRIISKNLYQAQ--RQPVPYGVLDRRMGISTKDAMCETCGQGLNECIGHFGYLDLALPVFHIGHFRSTINILQMICKVCAHVMLKPEDRQLYEKKLHNPNFSYLGKKALHVQMLAKAKKVTKCPHCGSPNGGVKKG-----PGLLKILHDPYKGRK--MDSLFTSNMNEMLRSTQTNRDLNSTLGNYSTAEELTPLMVLDLFEQIPQRDVALLGMCS--HDAHPKHLIVTRVFVPPACIRPSVLSEVKAGTTEDDLTMKQSEILLINDVIQRHMATGGKIELIHEDWDFLQLHVALYFHS------EISGIPINMAPKKTTRGIVQRLKGKQGRFRCNLSGKRVDFSGRTVISPDPNLMINQVGVPVRVAKILTYPERVNPANIRHMRELVRNGPSMHPGANYVQQRGSSFKKYLAYGNREKVAQELKCGDVVERHLRDGDIVLFNRQPSLHKMSIMCHRAKVQPQRTFRFNECACTPYNADFDGDEMNLHLPQTEEARAEALILMGNQSNLVTPKNGEILIAATQDFITGGYLLTQKEVFLTKEEAMQLAACFLANEDSTMHIKLPPPALLKPRRLWTGKQMFSLLMRPNDDSQVRLNMVNKGRNYT------RNKDLCSNDSWIHIRNSELMCGVMDKATMGSGTKQCIFYLLLRDFGESHATKAMWRLARIASYFLQNRGFSFGISDVTPSKKLLQHKELLLNNGYAKCNEYIELLKAGTLQCQPGCTPEETLESVMLRELSAIREQAAKTCFAELHPTNSALIMALSGSKGSNINISQMIACVGQQAISGKRVPNGFENRALPHFERHSAIPAARGFVQNSFYSGLTPTEFFFHTMAGREGLVDTAVKTAETGYLQRRLVKCLEDLVVHYDGTVRNAVNEMVDTIYGGDGLDPVSMETRNKPVDLVHQYDNLRAQHPQGKDRPLNAEEMSEALETLLR----------TPEFAEARDDFKL---------------DVRNHINTVSKRIGQLQKRY-------------------EKCID----LCHQIECLTTEQLLQFVRRINDRYNRAVTEPGTAVGAIAAQSIGEPGTQMTLKTFHFAGVASMNITQGVPRIVEIINATKTISTPIITAELENCHSMEFARQVKARIEKTTLAELSSYVEVVCGPYSCYLAIGVDMARIKLLGLHIDLDTIVFSILKS-RMRVKPTQVEVVAS-------------QSRIVVRVEATRTSTINAELARLALSLQNVVVAGLPNINRAVIAVDDARQPPTYKLCIEGYGLRDVIATYGVVGKRTRSNNICEIYQTLGIEAARTIIMSEITEVMEGHGMSVDWRHIMLLASQMTARGEVLGITRHGLAKMRESVFNLASFEKTADHLFDAAYYGQTDAINGVSERIILGMPACIGTGIFKLLQQHEDKQVPPI-EPTICSSLNLLPSKTT-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04051-1", "uniprot_id": "RPC1_YEAST", "id": "P04051-1", "name": "DNA-directed RNA polymerase III subunit RPC1", "aln": "--MKEVVVSETPKRIKGLEFSALSAADIVAQSEVEVSTRDLFDLEKDRAPKANGALDPKMGVSSSSLECATCHGNLASCHGHFGHLKLALPVFHIGYFKATIQILQGICKNCSAILLSETDKRQFLHELRRPGVDNLRRMGILKKILDQCKKQRRCLHCGALNGVVKKAAAGAGSAALKIIHDTFRWVGKKSAPEKDIWVGEWKEVLAHNPELERYVK--RCMDDLNPLKTLNLFKQIKSADCELLGIDATVPSGRPETYIWRYLPAPPVCIRPSVMMQDSPASNEDDLTVKLTEIVWTSSLIKAGLDKGISINNMMEHWDYLQLTVAMYINSDSVNPAMLPGSSNGGGKVKPIRGFCQRLKGKQGRFRGNLSGKRVDFSGRTVISPDPNLSIDEVAVPDRVAKVLTYPEKVTRYNRHKLQELIVNGPNVHPGANYLLKRNEDARRNLRYGDRMKLAKNLQIGDVVERHLEDGDVVLFNRQPSLHRLSILSHYAKIRPWRTFRLNECVCTPYNADFDGDEMNLHVPQTEEARAEAINLMGVKNNLLTPKSGEPIIAATQDFITGSYLISHKDSFYDRATLTQLLS---MMSDGIEHFDIPPPAIMKPYYLWTGKQVFSLLIKPNHNSPVVINLDAKNKVFVPPKSKSLPNEMSQNDGFVIIRGSQILSGVMDKSVLGDGKKHSVFYTILRDYGPQEAANAMNRMAKLCARFLGNRGFSIGINDVTPADDLKQKKEELVEIAYHKCDELITLFNKGELETQPGCNEEQTLEAKIGGLLSKVREEVGDVCINELDNWNAPLIMATCGSKGSTLNVSQMVAVVGQQIISGNRVPDGFQDRSLPHFPKNSKTPQSKGFVRNSFFSGLSPPEFLFHAISGREGLVDTAVKTAETGYMSRRLMKSLEDLSCQYDNTVRTSANGIVQFTYGGDGLDPLEMEGNAQPVNFNRSWDHAYNITFNNQDKGLLPYAIMETANEILGPLEERLVRYDNSGCLVKREDLNKAEYVDQYDAERDFYHSLREYINGKATALANLRKSRGMLGLLEPPAKELQGIDPDETVPDNVKTSVSQLYRISEKSVRKFLEIALFKYRKARLEPGTAIGAIGAQSIGEPGTQMTLKTFHFAGVASMNVTLGVPRIKEIINASKVISTPIINAVLVNDNDERAARVVKGRVEKTLLSDVAFYVQDVYKDNLSFIQVRIDLGTIDKLQLELTIEDIAVAITRASKLKIQASDVNIIGKDRIAINVFPEGYKAKSISTSAKEPSENDVFYRMQQLRRALPDVVVKGLPDISRAVINIRDDGKRE---LLVEGYGLRDVMCTDGVIGSRTTTNHVLEVFSVLGIEAARYSIIREINYTMSNHGMSVDPRHIQLLGDVMTYKGEVLGITRFGLSKMRDSVLQLASFEKTTDHLFDAAFYMKKDAVEGVSECIILGQTMSIGTGSFKVVKGTNISEKDLVPKRCLFESLSNEAALKAN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. : ::*. : *. .. :: :: :.: :::*:. : : * *.** :** * .. * ** .* .* **:*::.* ** **:*:*:: : *** *** *. ::*. :: : . *:.*.. * : .: :: :.:* * *.: ** *** . ***:*: :: . : . * ::: : ::*.** .*:**.:* * ** : . .:* * : .** ******: : ...:.*****:* :**: ..:*: .* . : : *.**:*** *:*::* :.* . . . * **: *********** ********************* *::*.** :***:**:**:*. * . :::*: ***.:*****:: :* . :: * **:* *:*::*: **:****: ***:**********::**:.* *:::* ****:***.****************:******:***: *** : **:**:.** :*** ***:**.**:: *: * : *: : .* :. :* *:::** ******:**::::*... * *: *.: : :::. **.:: *:.*:::.* ***..:*.*.*: :** :***:* ..*:.** *:*::.. :* *****:**.****.. * : * *:: .* **:* * :: * *: ****. *:***: : ** :*:.....*: **. *:.* ** .***** :*:***:* **** ***.***:**::*:**** ::* * ::*** :**:***:*.**:**:::*****************:.***:*.**** :** ***.:.. ::: ******** ** . :*::: : *: : * : : : :: :: : .:: .*: : : : :. . *: :: .: :*:. :* :* ***:*:**: *************************:* ***** *****:* ******.* * .. ** **.*:*** *.::: *:: * :: : :.: * * *.: : : :* : :::::. :* : . : . . . : : * * .*** *:*::.**** : : * :** .:* *:.* ** *.:* :*: *: ..******* *: ** .* .****:* **: **.. *: :**:*****.**:**::**: *******:*******:: :.*:: **** **:* . **** **::: : . . : .: . . ", "identical_positions": 553, "similar_positions": 415, "identity": "37.62%" }, { "cls_id": "homologset.agr.SGD:S000005643", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63569-1", "uniprot_id": "PRS6A_RAT", "id": "Q63569-1", "name": "26S proteasome regulatory subunit 6A", "aln": "---MNLLPTPESPVTRQEKMATVWDEAEQDGIGEEVLKMSTEEIVQRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPNDQEED------GANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEVQAKKKANLQYYA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88685-1", "uniprot_id": "PRS6A_MOUSE", "id": "O88685-1", "name": "26S proteasome regulatory subunit 6A", "aln": "MQEMNLLPTPESPVTRQEKMATVWDEAEQDGIGEEVLKMSTEEIVQRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPNDQEED------GANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEVQAKKKANLQYYA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17980-1", "uniprot_id": "PRS6A_HUMAN", "id": "P17980-1", "name": "26S proteasome regulatory subunit 6A", "aln": "---MNLLPNIESPVTRQEKMATVWDEAEQDGIGEEVLKMSTEEIIQRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPNDQEED------GANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEVQAKKKANLQYYA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3V6-1", "uniprot_id": "Q9V3V6_DROME", "id": "Q9V3V6-1", "name": "", "aln": "-----MAQTLED--------KSIWEDGE-ESLGEEVMRMSTDEIVSRTRLMDNEIKIMKSEVIRITHEIQAQNEKIKDNTEKIKVNKTLPYLVSNVIELLDVDPQEEEDD------GSVTVLDNQRKGKCAVIKTSTRQAYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPAEYDARVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLPMTHKEKFKNLGIHPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFSSTADIKVIAATNRVDILDPALLRSGRLDRKIEFPHPNEEARARIMQIHSRKMNVSNDVNFEELSRSTDDFNGAQCKAVCVEAGMIALRRSANSVTHEDFMDAIMEVQAKKKANLNYYA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33297-1", "uniprot_id": "PRS6A_YEAST", "id": "P33297-1", "name": "26S proteasome regulatory subunit 6A", "aln": "---MATLEELDA--------QTLPGDDE---LDQEILNLSTQELQTRAKLLDNEIRIFRSELQRLSHENNVMLEKIKDNKEKIKNNRQLPYLVANVVEVMDMNEIEDKENSESTTQGGNVNLDNTAVGKAAVVKTSSRQTVFLPMVGLVDPDKLKPNDLVGVNKDSYLILDTLPSEFDSRVKAMEVDEKPTETYSDVGGLDKQIEELVEAIVLPMKRADKFKDMGIRAPKGALMYGPPGTGKTLLARACAAQTNATFLKLAAPQLVQMYIGEGAKLVRDAFALAKEKAPTIIFIDELDAIGTKRFDSEKSGDREVQRTMLELLNQLDGFSSDDRVKVLAATNRVDVLDPALLRSGRLDRKIEFPLPSEDSRAQILQIHSRKMTTDDDINWQELARSTDEFNGAQLKAVTVEAGMIALRNGQSSVKHEDFVEGISEVQARKSKSVSFYA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: : * :.:*::.:**:*: *::*:*.**:*::**: *::** :. :***:*.**** *: *****:**:*::*:: ::::: *. **. **.**:***:**: ***::****.:****.*************:***:*:*:*********:*** ***:*******:**:**:****.: :**:::**:.***.*:*******************::******.******:**:*****************:*******************:*******************.. :**:*******:****************** *.*::**:*:*******... *:*::**:*.**:***** *** *********.. ..:.***:::.* ****:*. .:.:**", "identical_positions": 275, "similar_positions": 112, "identity": "61.38%" }, { "cls_id": "homologset.agr.SGD:S000005645", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q922Q2-1", "uniprot_id": "RIOK1_MOUSE", "id": "Q922Q2-1", "name": "Serine/threonine-protein kinase RIO1", "aln": "MDCSLDRMASVVPGQFDDADSSDS-------------ENKELQPIHAEDGGVLLKSLQNAAAEVK-GDAETDEEDDYDDDDD-WYLDDATG----KLTKG----CTWNGGSNYQANRQTSNYNSAKMSTPIDKSLRKFENKINLNKLNVTDSVTNKVTVKLRQKE-AESYRIKDKADRATVEQVLDPRTRMILFKLLHKDHISEIHGCISTGKEANVYYASTPSGES---------------------RAIKIYKTSILMFKDRDKYVTGEFRFRRGYCKGNPRKMVRTWAEKEMRNLCRLKT-ANIPCPEPIRLRSHVLLMGFIGK-DDMPAPLLKNVQLSE-SKARELYLQVIQYMRKMYQDARLVHADLSEFNMLYHGGDVYIIDVSQSVEHDHPHALEFLRKDCTNVNDFFSKHAVAVMTVRELFDFVTDPSITADN-MDAYLEKAMEIASQRTKEEKTSQDHVDEEVFKQAYIPRTLN--EVKNYERDVDIMMRLKEEDMALNTQQDNILYQTVMGLKKDLSGVQKVPALLESEVKEETCFGSDDAGGSECSDTVSEEQEDQAGCRNHIADPDID----KKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKAKKGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K5L3-1", "uniprot_id": "A0A0G2K5L3_RAT", "id": "A0A0G2K5L3-1", "name": "Serine/threonine-protein kinase RIO1", "aln": "MDCSLDRMATVVPGQFDDADSSDS-------------EDKEVQSIQAKDD-ILLKNLQNDAAEVK-GEDEIEEEDSYDYDSD-WYLDDSTG----KLTKG----WTWNGSSNHQANRQTSNYNSAKMSTPIDKSLRKFENKINLSKLNVTDSVINKVTVKLRQKE-AESYRIKDKADRATVEQVLDPRTRMILFKLLHKEHISEIHGCISTGKEANVYYASTPSGES---------------------RAIKIYKTSILMFKDRDKYVTGEFRFRRGYCKGNPRKMVKTWAEKEMRNLSRLRT-ANIPCPEPIRLRSHVLLMSFIGK-DDMPAPLLKNVQLSE-SKARELYLQVIQYMRKMYQDARLVHADLSEFNMLYHGGDVYIIDVSQSVEHDHPHALEFLRKDCANVNDFFFKHAVAVMTVKELFEFVTDPSITLEN-IDAYLEKAMEIASQRTMEEKTSQDHVDEEVFKQAYIPRTLN--EVKNYERDVDIMMRLKEEDMALNTQQDNILYQTVTGLKKDLSGVQKVPALLESEVKEETCFDSDDAGSSECSDTDPEEQGDQAGCQNHTADPDVD----KKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKAKKGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BRS2-1", "uniprot_id": "RIOK1_HUMAN", "id": "Q9BRS2-1", "name": "Serine/threonine-protein kinase RIO1", "aln": "MDYRRLLMSRVVPGQFDDADSSDS-------------ENRDLKTVKEKDD-ILFEDLQDNVNENGEGEIEDEEEEGYDDDDDDWDWDEGVG----KLAKG----YVWNGGSNPQANRQTSDSSSAKMSTPADKVLRKFENKINLDKLNVTDSVINKVTEKSRQKE-ADMYRIKDKADRATVEQVLDPRTRMILFKMLTRGIITEINGCISTGKEANVYHASTANGES---------------------RAIKIYKTSILVFKDRDKYVSGEFRFRHGYCKGNPRKMVKTWAEKEMRNLIRLNT-AEIPCPEPIMLRSHVLVMSFIGK-DDMPAPLLKNVQLSE-SKARELYLQVIQYMRRMYQDARLVHADLSEFNMLYHGGGVYIIDVSQSVEHDHPHALEFLRKDCANVNDFFMRHSVAVMTVRELFEFVTDPSITHEN-MDAYLSKAMEIASQRTKEERSSQDHVDEEVFKRAYIPRTLN--EVKNYERDMDIIMKLKEEDMAMNAQQDNILYQTVTGLKKDLSGVQKVPALLENQVEERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDID----KKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKTKKGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VTL5-1", "uniprot_id": "Q9VTL5_DROME", "id": "Q9VTL5-1", "name": "Serine/threonine-protein kinase RIO1", "aln": "MNNDSHKYSDAEEDEEDLRSSEWTNDFKNLTLKHEIFKDIKLTPKEDCDDLAQVIATANEEDEPEDEEPEEYDEDDYDDIGDDYDTYEEAYTGFNKLHVQPQLTNASGGGSGGGAGGASGGSQRVSSYQPNEKLLRRYSARINVEKYDPTTNMSAQAANRLVNFDRRDRTQVRDKHDRATAEQVMDPRTRMILFKLLNRGMIQEINGCISTGKEANVYHAVSKNGEEE--------------------FAIKIYKTSILVFKDRDKYVSGEFRFRHGYCKHNPRKMVRTWAEKEMRNYLRMRN-AGVPVPEPILLRSHVLVMRFCGR-DGWPAPKLKDVELST-SKARELYRDCVVIMWRIYNQCRLVHADLSEFNILLQDGQLVIIDVSQSVEHDHPHSFDFLRKDCTNISEFFRKRAVATMTVKELFDFITDQTITTEN-MEECLERISERIKDRDFDAISAQEKIDEAVWQNTYIPKRLD--EVRHFERDV---------AKAKQGVQQNLIYGKITGLTSDLDVQQKPDVLQSSTAKEDDGSEAQTSGSEDEDNSQDNDNDEDAKKFKNSARPREESPESKKARKKAVKDAKAEQRKVKVKKHVKKRKEKMGSMKK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12196-1", "uniprot_id": "RIO1_YEAST", "id": "Q12196-1", "name": "Serine/threonine-protein kinase RIO1", "aln": "--------------------------------------------------------------------------------------------------------------MSLEDKFDSLSVSQGASDHINNQLLEKYSHKIKTDELSFSRAKTS-----------------KDKANRATVENVLDPRTMRFLKSMVTRGVIADLNGCLSTGKEANVYHAFAGTGKAPVIDEETGQYEVLETDGSRAEYAIKIYKTSILVFKDRERYVDGEFRFRNSRSQHNPRKMIKIWAEKEFRNLKRIYQSGVIPAPKPIEVKNNVLVMEFLSRGNGFASPKLKDYPYKNRDEIFHYYHTMVAYMRLLYQVCRLVHADLSEYNTIVHDDKLYMIDVSQSVEPEHPMSLDFLRMDIKNVNLYFEKMGISIFPERVIFQFVISETLEKFKGDYNNISALVAYIASNLPIKSTEQDEAEDEIFRSLHLVRSLGGLEERDFDRYTDGKFDLLKSLIAHDNERNFAASEQFEFDNADHECSSGTEEFSDDEEDGSSGSEEDDEEEGEYYD------DDEPKVLKGKKHEDKD---LKKLRKQEAKDAKREKRKTKVKKHIKKKLVKKTKSKK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . :: *.::. :*: .: . : :** :***.*:*:**** :* .:: : * :::**:*********:* : .*: **********:****::** ******.. .: *****:: *****:** *: . :* *:** ::.:**:* * .: :. .:* **: . .: . * : * :*: .*********:* : :.. : :******** :** :::*** * *:. :* : .:: :. : :*:*: . :: : :. .. : *:. :: ::: :: : *. * :.::* * : :: . . * . . : .. . : : : :.. : : ** **: .*:*: *:** *: **:**: * . ** ", "identical_positions": 128, "similar_positions": 144, "identity": "20.58%" }, { "cls_id": "homologset.agr.SGD:S000005646", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51652-1", "uniprot_id": "AKC1H_RAT", "id": "P51652-1", "name": "Aldo-keto reductase family 1 member C18", "aln": "-------------------------------MNSKIQ-----KMELNDGHSIPVLGFGTYAT-------------------------------------------EENLRKKSMESTKIAIDVGFRHIDCSHLYQNEEEIGQAIVSKIE-DGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKP------GDELLPQDEHGNLILDTV--DLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKHRPVCNQVECHLYLNQSKLLAYCKM-NDIVLVAYGALGTQRYKYCINEDTPV----LLDDPILCTMAKKYKRTPALIALRYQLERGIVTLVKSFNEERIRENLQVFDFQLASDDMEILDNLDRNLRYFPAN---------MFKAHPNF-PFS-DEY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K023-1", "uniprot_id": "AKC1H_MOUSE", "id": "Q8K023-1", "name": "Aldo-keto reductase family 1 member C18", "aln": "-------------------------------MNSKIQ-----KIELNDGHSIPVLGFGTYAT-------------------------------------------EEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEEIGQAILSKIE-DGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKP------GNELLPKDEHGNLIFDTV--DLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHLYLNQSKLLAYCKM-NDIVLVAYGALGTQRYKYCINEDTPV----LLDDPVLCAMAKKYKRTPALIALRYQLDRGIVALAKSFNEERIRENMQVFDFQLASDDMKILDGLDRNLRYFPAD---------MFKAHPNF-PFF-DEY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23457-1", "uniprot_id": "DIDH_RAT", "id": "P23457-1", "name": "3-alpha-hydroxysteroid dehydrogenase", "aln": "-------------------------------MDSISL-----RVALNDGNFIPVLGFGTTVP-------------------------------------------EKVAKDEVIKATKIAIDNGFRHFDSAYLYEVEEEVGQAIRSKIE-DGTVKREDIFYTSKLWSTFHRPELVRTCLEKTLKSTQLDYVDLYIIHFPMALQP------GDIFFPRDEHGKLLFETV--DICDTWEAMEKCKDAGLAKSIGVSNFNCRQLERILNKPGLKYKPVCNQVECHLYLNQSKMLDYCKS-KDIILVSYCTLGSSRDKTWVDQKSPV----LLDDPVLCAIAKKYKQTPALVALRYQLQRGVVPLIRSFNAKRIKELTQVFEFQLASEDMKALDGLNRNFRYNNAK---------YFDDHPNH-PFT-DE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6AYQ2-1", "uniprot_id": "AK1CL_RAT", "id": "Q6AYQ2-1", "name": "Aldo-keto reductase family 1 member C21", "aln": "-------------------------------MNSKCH-----CVKLNDGHFIPVLGFGTAMP-------------------------------------------SELPKSKAKEVTKIAIDAGFHHFDSAFVYNTEDHVGEAIREKIA-NGTTRREDIFYTSKLWCTSLHPELVRSSLECSLKKLQLDYVDLYLIHFPMALKP------GDENFPVDEHGKLLFDTV--DLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKYKPVCNQVECHLYLNQMKLLDFCKT-NGIILVAYGVLGTQRYNGWVDQNSPV----LLNEPVLSSMAKKYNQTPALIALRHQLQRGIVVLNTSLKEERIKENMK-----LSPEDMKVLDDLNRNLRYIAGG---------IFEGHPNF-PFL-DEY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WR5-1", "uniprot_id": "AK1CL_MOUSE", "id": "Q91WR5-1", "name": "Aldo-keto reductase family 1 member C21", "aln": "-------------------------------MNSKCH-----CVILNDGNFIPVLGFGTALP-------------------------------------------LECPKSKAKELTKIAIDAGFHHFDSASVYNTEDHVGEAIRSKIA-DGTVRREDIFYTSKVWCTSLHPELVRASLERSLQKLQFDYVDLYLIHYPMALKP------GEENFPVDEHGKLIFDRV--DLCATWEAMEKCKDAGLTKSIGVSNFNYRQLEMILNKPGLKYKPVCNQVECHPYLNQMKLLDFCKS-KDIVLVAYGVLGTQRYGGWVDQNSPV----LLDEPVLGSMAKKYNRTPALIALRYQLQRGIVVLNTSLKEERIKENMQVFEFQLSSEDMKVLDGLNRNMRYIPAA---------IFKGHPNW-PFL-DEY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P70694-1", "uniprot_id": "DHB5_MOUSE", "id": "P70694-1", "name": "Estradiol 17 beta-dehydrogenase 5", "aln": "-------------------------------MDSKQQ-----TVRLSDGHFIPILGFGTYAP-------------------------------------------QEVPKSKATEATKIAIDAGFRHIDSASMYQNEKEVGLAIRSKIA-DGTVKREDIFYTSKVWCTFHRPELVRVCLEQSLKQLQLDYVDLYLIHFPMAMKP------GENYLPKDENGKLIYDAV--DICDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILKKPGLKYKPVCNQVECHPYLNQGKLLDFCRS-KDIVLVAYSALGSHREKQWVDQSSPV----LLDNPVLGSMAKKYNRTPALIALRYQLQRGVVVLAKSFSEKRIKENMQVFEFQLTSEDMKVLDDLNKNIRYISGS---------SFKDHPDF-PFW-DEY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04828-1", "uniprot_id": "AK1C1_HUMAN", "id": "Q04828-1", "name": "Aldo-keto reductase family 1 member C1", "aln": "-------------------------------MDSKYQ-----CVKLNDGHFMPVLGFGTYAP-------------------------------------------AEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIA-DGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP------GEEVIPKDENGKILFDTV--DLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKS-KDIVLVAYSALGSHREEPWVDPNSPV----LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLD---------IFAGPPNY-PFS-DEY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52895-1", "uniprot_id": "AK1C2_HUMAN", "id": "P52895-1", "name": "Aldo-keto reductase family 1 member C2", "aln": "-------------------------------MDSKYQ-----CVKLNDGHFMPVLGFGTYAP-------------------------------------------AEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIA-DGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP------GEEVIPKDENGKILFDTV--DLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKS-KDIVLVAYSALGSHREEPWVDPNSPV----LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLD---------IFAGPPNY-PFS-DEY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P42330-1", "uniprot_id": "AK1C3_HUMAN", "id": "P42330-1", "name": "Aldo-keto reductase family 1 member C3", "aln": "-------------------------------MDSKHQ-----CVKLNDGHFMPVLGFGTYAP-------------------------------------------PEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIA-DGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP------GEELSPTDENGKVIFDIV--DLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKS-KDIVLVAYSALGSQRDKRWVDPNSPV----LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSD---------SFASHPNY-PYS-DEY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17516-1", "uniprot_id": "AK1C4_HUMAN", "id": "P17516-1", "name": "Aldo-keto reductase family 1 member C4", "aln": "-------------------------------MDPKYQ-----RVELNDGHFMPVLGFGTYAP-------------------------------------------PEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIA-DGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP------GETPLPKDENGKVIFDTV--DLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKS-KDIVLVAHSALGTQRHKLWVDPNSPV----LLEDPVLCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMD---------FLMDHPDY-PFS-DEY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VC28-1", "uniprot_id": "AK1CD_MOUSE", "id": "Q8VC28-1", "name": "Aldo-keto reductase family 1 member C13", "aln": "-------------------------------MSSKQH-----CVKLNDGHLIPALGFGTYK-------------------------------------P------KEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQSKIK-AGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMKS------GDNDFPVNEQGKSLLDTV--DFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKPVCNQVECHLYLNQRKLLDYCES-KDIVLVAYGALGTQRYKEWVDQNSPV----LLNDPVLCDVAKKNKRSPALIALRYLIQRGIVPLAQSFKENEMRENLQVFGFQLSPEDMKTLDGLNKNFRYLPAE---------FLVDHPEY-PFV-EEY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AD50-1", "uniprot_id": "A0A8I6AD50_RAT", "id": "A0A8I6AD50-1", "name": "", "aln": "-------------------------------MAASCHYWAMALFKIQSSEYVNQISFGQAEYVAYLQRAEGRMSPLSEPEQAAGFLQVMRHCSCCLCSPGVSASYKLVPKSKSLEAAHLAIDAGYRHIDTAYAYQIEEEIGQAIQSKIK-AGVVKREDMFITTKLWCTCFRPELVKPALEKSLKNLQLDYADLYIMHYPVPMKS------GDNDFPVDEKGKSLLDTV--DFCDTWEMLEKCKDAGLVKSIGVSNFNHKQLERLLNKPGLKYKPVCNQVECHLYLNQSKLLDYCKS-KDIVLVAYGALGTQRYKEWVDQNSPV----LLNDPVLCDVAKKNKRSPALIALRYLVQRGVVPLAQSFKENEMRENLQVFDFQLSPEDMKTLDGLNKNFRYLSAE---------FLAGHPEY-PFS-EEY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3X9Y6-1", "uniprot_id": "G3X9Y6_MOUSE", "id": "G3X9Y6-1", "name": "", "aln": "-------------------------------MSSKQQ-----CVKLNDGNFIPALGFGTYK-------------------------------------P------EEVNENKPLEAIHLALEAGFRHIDTAYVYQTENHVGQAIRSKIA-AGLVKREDIFLTTKLWCTFHRPELVRSNLEKSLKNLQLDYADLYLIHYPVQMKP------GEDLFPEDEHGKTLFDTV--DICATWEAMEKCKDAGLVKSIGVSNFNSRQLEKILNKPGLKYKPVCNQVECHLYLNQRKLLNYCKS-KDIVLVAYCALGSQRPKRWVDPSSPV----LLNDPILCDMAKKHKRSPAQIALRYHLQRGIVVLAQSYKENEIKENIQVFEFELPSEDMKILDSLDRNLRYAPAP---------FGEGHPEY-PFS-DEF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ADN4-1", "uniprot_id": "A0A8I6ADN4_RAT", "id": "A0A8I6ADN4-1", "name": "", "aln": "-------------------------------MSFKQQ-----CVELSDGRLMPLLGYGTFQ----------------------------------------------------------------------------------------------------NPELWSTFHRPELVRVGLERSLKSFQLDYVDLYLIHYPISIKP------SEEIYTKDENGKILFETV--DLCAIWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKHRPVCNQVECHPYLNQSKLMDFCKS-QDIVLVAYAALGSQRPTNWVDKNAPF----LLNDPVLGGMAKKHNRSPAQIALRYQVQRGVVALAQTYEQKEMKENIQVFEFQLPSEDMEVLDGLNRNFRYFPVN---------IAAEHPNY-PYS-DDY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZF77-1", "uniprot_id": "AK1CA_RAT", "id": "D3ZF77-1", "name": "Aldo-keto reductase family 1 member C15", "aln": "-------------------------------MDLKHSR----SVKLNDGNLMPVLGFGTFAS-------------------------------------------KEIPKSKAAEATKVAIDVGFRHIDAAYFYQNEEEVGQALRDKMA-DGTVKREDLFYTTKIWITFLRPELVRQCLERSLKKLGLDYVDLCIIHIPIAMKP------GEELLPKDANGKFIFDTV--DIRDTWEALEKCKDAGLSKSIGVSNFNHKQLELILNKPRLKYKPTCNQVECHPYLNQSKLLEFCKS-KDIVLVAYSALGSHRDSSWVSSDSPY----LLEDPVLMTIAKKHNQTPGQVALRYQLQRGVVVLAKSFNEKRIKENFQVFDFELTPEDMKTIDSLNRNFRYSQMA---------FALDHPDY-PFL-EEY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCX1-1", "uniprot_id": "AK1D1_MOUSE", "id": "Q8VCX1-1", "name": "Aldo-keto reductase family 1 member D1", "aln": "-------------------------------MNLSAAH---HQISLSDGNNIPLIGLGTYSDP------------------------------------------RPVP-GKTYVAVKTAIDEGYRHIDGAYVYHNEHEVGEAIREKIA-EGKVKREEIFYCGKLWNTEHVPSMVLPALERTLKALKLDYIDLYIIELPMAFKP------GKEIYPRDENGRIIYDKT--NLCATWEALEACKDAGLVKSLGVSNFNRRQLELILNKPGLKYKPVTNQVECHPYFTQTKLLKFCQQ-HDIVIVAHSPLGTCRNPSWVNVSSPP----LLNDELLTSLGKKYNKTQAQIVLRFNIQRGIVVIPKSFTPERIKENFQIFDFSLTEEEMKDIDALNKNVRYVELL---------MWSDHPEY-PFH-DEY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31210-1", "uniprot_id": "AK1D1_RAT", "id": "P31210-1", "name": "Aldo-keto reductase family 1 member D1", "aln": "-------------------------------MNLSTAN---HHIPLNDGNSIPIIGLGTYSDP------------------------------------------RPVP-GKTFIAVKTAIDEGYRHIDGAYVYRNEHEVGEAIREKVA-EGKVKREEIFYCGKLWSTDHDPEMVRPALERTLQTLKLDYIDLYIIEMPMAFKP------GEEFYPKDENGRVIYHKS--NLCATWEALEACKDAGLVKSLGVSNFNRRQLEVILNKPGLKYKPVTNQVECHPYFTQTKLLEVSASSMTSFIVAYSPLGTCRNPLWVNVSSPP----LLKDELLTSLGKKYNKTQAQIVLRFDIQRGLVVIPKSTTPERIKENFQIFDFSLTKEEMKDIEALNKNVRFVEML---------MWSDHPEY-PFH-DEY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51857-1", "uniprot_id": "AK1D1_HUMAN", "id": "P51857-1", "name": "Aldo-keto reductase family 1 member D1", "aln": "-------------------------------MDLSAAS---HRIPLSDGNSIPIIGLGTYSEP------------------------------------------KSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIA-EGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP------GDEIYPRDENGKWLYHKS--NLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQ-HDIVITAYSPLGTSRNPIWVNVSSPP----LLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVELL---------MWRDHPEY-PFH-DEY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y112-1", "uniprot_id": "Q9Y112_DROME", "id": "Q9Y112-1", "name": "NADP-dependent oxidoreductase domain-containing protein", "aln": "-------------------------------MSSKIP-----YVKHNNGTQIQSIGLGTYTS----------------------------------------------LGGDCERATLHAIDVGYRHIDTAYFYENENEVGAAVQRKIA-EGVIKREDIHITTKLWCHFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPYSYVYR----GDNEMMPTDAKGEVELNDI--DYLDTWREMEKLVELGLTKSIGVSNFNSEQLTRLLAN--CKIKPIHNQIECHPALNQKKLIALCKK-NDIVVTAYCPLGRPNP----AEKTPN----YIYDAKVQAIGDKYKKSTAQVVLRYLIEIGTIPLPKSSNPKRIEENFQIFDFQLDAEDHAILDSYNTGERLIPMT---------HAIKSKNY-PFN-IEF---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZK8-1", "uniprot_id": "Q9VZK8_DROME", "id": "Q9VZK8-1", "name": "NADP-dependent oxidoreductase domain-containing protein", "aln": "-------------------------------MTGKVEY----YFKHNDGTHIQGIGLGTFAS----------------------------------------------TEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIA-EGVIKREDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYR----GDNELIPKDANGEVELVDI--DYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLLAN--CKIKPIHNQIEVHPALDQKKLIALCKK-NGILVTAFSPLGRHNA----ELRTPT----FMYDGKVQAIADKYNKSIAQVVIRYVIELGTIPLPKSSNPKRIEENFNVFDFKLDAEDHAILDSYHNGERVAHAR---------QAIKSKYY-PFN-VYSACF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTY2-1", "uniprot_id": "Q9VTY2_DROME", "id": "Q9VTY2-1", "name": "NADP-dependent oxidoreductase domain-containing protein", "aln": "---------------------------------MKLAP----TVKLNNGYEMPILGLGTYNS----------------------------------------------KDNEGEAAVKHAIDVGYRHIDTAYFYQNEAEVGKAIRDKIA-EGVVKREDIFLVTKLWNIFHDPERVEGICRKQLSNFGLDYIDLYLMHMPVGYKYV----DDNTLLPKNEDDVLQLSDV--DYLDTYKAMEKLVKLGLVRSIGVSNFNSEQLARVLAN--CEIKPVTNQVECSPALNQKALTAFCKK-NDVTLTGYTPLGKPKP----DIQKPD----FIYSPEVAVIAKKYGKTTPQIVLRYLVGLGVIPIPKSSNTNRISENFDIFDFELTAEEMAVLDGYHTGERVVPLNL-------IKGLNHKYY-PFS-IEF---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q5RJP0-1", "uniprot_id": "ALD1_RAT", "id": "Q5RJP0-1", "name": "Aldo-keto reductase family 1 member B7", "aln": "-----------------------------------MTT----FVKLRTKAKMPLVGLGTWKSP----------------------------------------------PGQVKEAVKAAIDAGYRHFDCAYVYQNESEVGEAIQEKIK-EKAVRREDLFIVSKLWSTFFEKSLMKEAFQKTLSDLKLDYLDLYLIHWPQGLQ------AGKEFLPKDSQGKVLMSKS--TFLDAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHS-KGIAVIAYSPLG-SPDRPYAKPEDPV----VLEIPKIKEIAAKHKKTIAQVLIRFHVQRNVAVIPKSVTLSHIKENIQVFDFQLSEEDMAAILSLNRNWRACG---------LFVTSDEEDF-PFH-EEY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21300-1", "uniprot_id": "ALD1_MOUSE", "id": "P21300-1", "name": "Aldo-keto reductase family 1 member B7", "aln": "-----------------------------------MAT----FVELSTKAKMPLVGLGTWKSS----------------------------------------------PGQVKEAVKAAIDAGYRHIDCAYVYHNENEVGEAIQEKIK-ENAVKREDLFIVSKLWATFFEKSLVKKAFQNTLSDLKLDYLDLYLVHWPQGFQ------AGNALLPKDNKGKVLLSKS--TFLDAWEAMEELVDQGLVKALGISNFNHFQIERLLNKPGLKHKPVTNQIESHPYLTQEKLIQYCQS-KGIAVTAYSPLG-SPDRPYAKPEDPV----VMEIPKIKEIAAKHKKTVAQVLIRFHVQRNVVVIPKSVTPSRIQENLQVFDFQLSEEDMAAILSFNRNWRACD---------LLDARTEEDY-PFH-EEY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G5E895-1", "uniprot_id": "G5E895_MOUSE", "id": "G5E895-1", "name": "aldose reductase", "aln": "-----------------------------------MAA----FVTLLTGAKMPIVGLGTWKSP----------------------------------------------PAKVREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQEKIQ-EKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQ------SGNVFLPTDDKGSILSSKY--TFLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHS-KGITITAYSPLG-SPDRPSAKPEDPL----LLEIPKIKEIAAKHKRTAAQVLIRFHIERNVVVIPKSVTPSRIQENIQVFDFQLSEEDMAAILSFNRNWRACG---------LFAASHNEDF-PFH-AEY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P45377-1", "uniprot_id": "ALD2_MOUSE", "id": "P45377-1", "name": "Aldose reductase-related protein 2", "aln": "-----------------------------------MAT----FVELSTKAKMPIVGLGTWKSP----------------------------------------------PNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQEKIK-EKAVQREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQ------PGKELFPKDDQGRILTSKT--TFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHS-KGISVTAYSPLG-SPDRPSAKPEDPS----LLEDPKIKEIAAKHEKTSAQVLIRFHIQRNVVVIPKSVTPSRIQENIQVFDFQLSDEEMATILSFNRNWRACL---------LPETVNMEEY-PYD-AEY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60218-1", "uniprot_id": "AK1BA_HUMAN", "id": "O60218-1", "name": "Aldo-keto reductase family 1 member B10", "aln": "-----------------------------------MAT----FVELSTKAKMPIVGLGTWKSP----------------------------------------------LGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ-EKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK------SGDDLFPKDDKGNAIGGKA--TFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHS-KGITVTAYSPLG-SPDRPWAKPEDPS----LLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN---------VLQSSHLEDY-PFN-AEY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "C9JRZ8-1", "uniprot_id": "AK1BF_HUMAN", "id": "C9JRZ8-1", "name": "Aldo-keto reductase family 1 member B15", "aln": "-----------------------------------MAT----FVELSTKAKMPIVGLGTWRSL----------------------------------------------LGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQEKIQ-EKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK------TGDDFFPKDDKGNMISGKG--TFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHS-KGITVTAYSPLG-SPDRPWAKPEDPS----LLEDPKIKEIAAKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRNWRAFD---------FKEFSHLEDF-PFD-AEY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07943-1", "uniprot_id": "ALDR_RAT", "id": "P07943-1", "name": "Aldo-keto reductase family 1 member B1", "aln": "-----------------------------------MAS----HLELNNGTKMPTLGLGTWKSP----------------------------------------------PGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQEKLK-EQVVKRQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFK------PGPDYFPLDASGNVIPSDT--DFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHC-KGIVVTAYSPLG-SPDRPWAKPEDPS----LLEDPRIKEIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPARIAENFKVFDFELSNEDMATLLSYNRNWRVCA---------LMSCAKHKDY-PFH-AEV---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6A068-1", "uniprot_id": "A0A8I6A068_RAT", "id": "A0A8I6A068-1", "name": "aldose reductase", "aln": "-----------------------------------MAS----YLELNSGTKMPTLGLGTWKSP----------------------------------------------PGQVTEAVKVAIDMGYRHIDCTRVFQNEKEVGVALQEKLK-EQVVKRQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLTHWPTGFK------PGPDYFPLDALGNVIPSDT--DFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHC-KGIMVTAYSPLG-SPDRPWAKPEDPS----LLEDPRIKEIAAKYNKTTAQVLIWFPIQRNLVVIPKSVTPARIADNFKVFDFELSSEDMATLLSYNRNWRVCA---------LMSCVKHKDY-PFH-AEV---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P45376-1", "uniprot_id": "ALDR_MOUSE", "id": "P45376-1", "name": "Aldo-keto reductase family 1 member B1", "aln": "-----------------------------------MAS----HLELNNGTKMPTLGLGTWKSP----------------------------------------------PGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLK-EQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFK------PGPDYFPLDASGNVIPSDT--DFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHS-KGIVVTAYSPLG-SPDRPWAKPEDPS----LLEDPRIKAIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPVRIAENLKVFDFEVSSEDMATLLSYNRNWRVCA---------LMSCAKHKDY-PFH-AEV---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15121-1", "uniprot_id": "ALDR_HUMAN", "id": "P15121-1", "name": "Aldo-keto reductase family 1 member B1", "aln": "-----------------------------------MAS----RLLLNNGAKMPILGLGTWKSP----------------------------------------------PGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR-EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFK------PGKEFFPLDESGNVVPSDT--NILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS-KGIVVTAYSPLG-SPDRPWAKPEDPS----LLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA---------LLSCTSHKDY-PFH-EEF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DCT1-1", "uniprot_id": "AKCL2_MOUSE", "id": "Q9DCT1-1", "name": "1,5-anhydro-D-fructose reductase", "aln": "------------------------------------------------MENIPTVGLGTWKAS----------------------------------------------PGEVTDAVKLAINLGYRHFDCAYLYHNESEVGMGISEKIK-EGVVKREDLFVVSKLWCTCHKKSLVKTACTNTLEALNLDYLDLYLIHWPMGFK------PGEKDIPLDRNGKVIPSHT--SFLDTWEAMEDLVFEGLVKNLGVSNFNHEQLERLLDKPGLRVRPITNQIECHPYLNQKKLIDFCHK-RNVSVTAYRPLG-GSG------GGFH----LMDDTVIRKIAKKHGKSPAQILIRFQIQRNLIVIPKSVTPSRIRENIQVFDFELTEKDMEELLSLDKNLRLAT---------FPTTENHQDY-PFH-IEY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U1Y4-1", "uniprot_id": "AKCL2_RAT", "id": "Q5U1Y4-1", "name": "1,5-anhydro-D-fructose reductase", "aln": "------------------------------------------------MHQIPTVGLGTWKAS----------------------------------------------PGEVTDAVKVAINLGYRHFDCAYLYHNESEVGMGIKEKIK-EGVVKRDELFIVSKLWCTYHKQSLVKTACINTLEALNLDYLDLYLIHWPMGFK------PGDKDIPLDRSGKVIPSHT--SFLDTWEAMEDLVIEGLVKNIGVSNFNHEQLDRLLNKPGLRIKPITNQIECHPYLNQKSLIDFCHG-RNVSVTAYRPLG-GSR------DGVH----LMDDIVIRKIAKKHGKSPAQILIRFQIQRNLIVIPKSVNPSRIRENIQVFDFELTEKDMEELLSLDKNLRLAT---------FPSTENHKDY-PFH-IEY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M9PF61-1", "uniprot_id": "ALDR_DROME", "id": "M9PF61-1", "name": "Aldo-keto reductase 1B", "aln": "MNTLMKIQLVRPVFRITLRNYGKPERFMWCQKEYARAP----KVVCLDGNEIPVIGLGTFNSP----------------------------------------------KGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIK-EGVVKREDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYK------EGCDLFPTDKDGKTLYSPV--DYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATIP--PVTNQIECHPYLTQKKLIDFCKS-KDITITAYSPLG-SPNRPWAKAGDPV----ILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKSVTKDRIESNFQVFDFELTPEEIEIIESFECNGRLVP---------LLNQYGHPHH-PFEKDEY---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P51635-1", "uniprot_id": "AK1A1_RAT", "id": "P51635-1", "name": "Aldo-keto reductase family 1 member A1", "aln": "----------------------------------MTAS----SVLLHTGQKMPLIGLGTWKSE----------------------------------------------PGQVKAAIKYALSVGYRHIDCASVYGNETEIGEALKESVGAGKAVPREELFVTSKLWNTKHHPEDVEPAVRKTLADLQLEYLDLYLMHWPYAFE------RGDNPFPKNADGTVKYDST--HYKETWKALEALVAKGLVKALGLSNFSSRQIDDVLSVASVR--PAVLQVECHPYLAQNELIAHCQA-RGLEVTAYSPLG-SSDRAWRHPDEPV----LLEEPVVLALAEKHGRSPAQILLRWQVQRKVICIPKSITPSRILQNIQVFDFTFSPEEMKQLDALNKNWRYIVPMITVDGKRVPRDAGHPLY-PFN-DPY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JII6-1", "uniprot_id": "AK1A1_MOUSE", "id": "Q9JII6-1", "name": "Aldo-keto reductase family 1 member A1", "aln": "----------------------------------MTAS----SVLLHTGQKMPLIGLGTWKSE----------------------------------------------PGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKESVGSGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFE------RGDNPFPKNADGTVRYDST--HYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVR--PAVLQVECHPYLAQNELIAHCHA-RGLEVTAYSPLG-SSDRAWRHPDEPV----LLEEPVVLALAEKHGRSPAQILLRWQVQRKVICIPKSINPSRILQNIQVFDFTFSPEEMKQLDALNKNWRYIVPMITVDGKRVPRDAGHPLY-PFN-DPY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14550-1", "uniprot_id": "AK1A1_HUMAN", "id": "P14550-1", "name": "Aldo-keto reductase family 1 member A1", "aln": "----------------------------------MAAS----CVLLHTGQKMPLIGLGTWKSE----------------------------------------------PGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFE------RGDNPFPKNADGTICYDST--HYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR--PAVLQVECHPYLAQNELIAHCQA-RGLEVTAYSPLG-SSDRAWRDPDEPV----LLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLY-PFN-DPY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q568L5-1", "uniprot_id": "A1A1B_DANRE", "id": "Q568L5-1", "name": "Aldo-keto reductase family 1 member A1-B", "aln": "-----------------------------------MND----FAVLSTGRKMPLLGLGTWKSE----------------------------------------------PGLVKQAVIWALESGYRHIDCAPIYANEPEIGEAFQETMGPDKGIRREDVFVTSKLWNTKHHPDDVEPSLLKTLKDLKLEYLDLYLIHWPYAFQ------RGDTPFPRKEDGTLLYDDI--DYKLTWAAMEKLVGKGLVRAIGLSNFNSRQIDDILSVASIK--PTVLQVESHPYLAQVELLSHCRD-RGLVMTAYSPLG-SPDRAWKHPDEPV----LLEEPAIAALAKKYNKTPAQIIIRWQTQRGVVTIPKSITQSRIKENIQVFDFTLESEEMSQVTALHRGWRYIVPTITVDGKSVPRDAGHPHY-PFN-DPY---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6AZW2-1", "uniprot_id": "A1A1A_DANRE", "id": "Q6AZW2-1", "name": "Aldo-keto reductase family 1 member A1-A", "aln": "-----------------------------------MTA----TITLSTGQRMPTVGLGTWKSA----------------------------------------------PGQVKQAVLAALDCGYRHIDCAAAYSNEREVGEALTERLGPGKSLRRDDIFVTSKLWNTKHHPDDVEEACRRSLSDLRLSYLDLYLIHWPMAFG------RGDELIPRHPDGTIQYDDT--HYRDTWAAMEKLVDQGLAKAIGLSNFNAKQIDDILSIAKHK--PVVNQVECHPYLVQAELVSHCWS-RNLTVTAYSPLG-SPDRPWVTPGEAL----LLDDPRVVGIAKSYNKTPAQVIIRWHIQRGVVCIPKSVTPSRIKQNIEVFDFKLSDEDMRLIESFNRNERFIIPTVIKDGQKIWRDAKHPHF-PFI-EPY---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1PA35-1", "uniprot_id": "A0A8M1PA35_DANRE", "id": "A0A8M1PA35-1", "name": "alcohol dehydrogenase (NADP(+))", "aln": "-----------------------------MEEGVQKPR----KIELNDGTFMPLLGLGTWKPES-------------------------------------------TGPDMCQRACEAAIAAGYRHIDTAFCYRNEVDVGMAIQNKIQ-QGIIRRQDMFIVSKLWGTHHAPEDIPVCFNKSLSDLQLDYLDQYLVHFPVGLKK-----VGDELFP-ERDGKILTTDI--DYVDVWRGMEALKATGKVKSIGVSNFTMEQIDRLLSVAKIP--PAVNQVELHPYLVQSDLIDYCKS-KNIALTAHSPFG-SPGRPLEFQTGDKDPMGLLEDPVVVDVARKHRRTPAQVLLRYHIQQDIAVIPKSVKPHHILENTKIFDFTLDEEDMNALKSLNRGWRACI---------ITELEAHYFY-PFK-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P14065-1", "uniprot_id": "GCY1_YEAST", "id": "P14065-1", "name": "Glycerol 2-dehydrogenase (NADP(+))", "aln": "-------------------------------MPATLHDS-TKILSLNTGAQIPQIGLGTWQSK----------------------------------------------ENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIK-----DSGVPREEIFVTTKLWCTQHHEP--EVALDQSLKRLGLDYVDLYLMHWPARLDPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQGNKLTPAANQVEIHPLLPQDELINFCKS-KGIVVEAYSPLG---------STDAP----LLKEPVILEIAKKNNVQPGHVVISWHVQRGYVVLPKSVNPDRIKTNRKIFT--LSTEDFEAINNISKEKGEKR-------------VVHPNWSPFEVFK----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. * ::* * :.* * : . * . . . . : :: * : :*:***. : :* * *:* : : : . : .. :* : : :. : : : : .: . . .: : *: ", "identical_positions": 17, "similar_positions": 47, "identity": "3.95%" }, { "cls_id": "homologset.agr.SGD:S000005648", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5IRJ7-1", "uniprot_id": "PROF4_RAT", "id": "Q5IRJ7-1", "name": "Profilin-4", "aln": "MSHLQNLLLDTLLGTKHVDGAALIKLQEKTLCVTSPGFSVMPCDVRTLLNGFAKNPLLTRREGLYFREKDYKCVRADDCSLYAKKENTGVVVVKTHMYLLVATYTAGMYPSVCVEATEKLGEYLRKKGN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D6I3-1", "uniprot_id": "PROF4_MOUSE", "id": "Q9D6I3-1", "name": "Profilin-4", "aln": "MSHLQNLLLDTLLGTKHVDSAALIKLQEKTLCVTSPGFSVMPSDVRTLLNGFAKNPLLTRREGLYFKEKDYKCVRADDYSLYAKNENTGVVVVKTNMYLVVATYTAGMYPSVCVEATEKLGEYLRKKGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NHR9-1", "uniprot_id": "PROF4_HUMAN", "id": "Q8NHR9-1", "name": "Profilin-4", "aln": "MSHLQSLLLDTLLGTKHVDSAALIKIQERSLCVASPGFNVTPSDVRTLVNGFAKNPLQARREGLYFKGKDYRCVRADEYSLYAKNENTGVVVVKTHLYLLVATYTEGMYPSICVEATESLGDYLRKKGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07274-1", "uniprot_id": "PROF_YEAST", "id": "P07274-1", "name": "Profilin", "aln": "-MSWQAYTDN-LIGTGKVDKAVIYSRAGDAVWATSGGLSLQPNEIGEIVQGFDNPAGLQS-NGLHIQGQKFMLLRADDRSIYGRHDAEGVVCVRTKQTVIIAHYPPTVQAGEATKIVEQLADYLIGVQY", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P25843-1", "uniprot_id": "PROF_DROME", "id": "P25843-1", "name": "Profilin", "aln": "-MSWQDYVDNQLLASQCVTKACIAGHDGN-IWAQSSGFEVTKEELSKLISGFDQQDGLTS-NGVTLAGQRYIYLSGTDRVVRAKLGRSGVHCMKTTQAVIVSIYEDPVQPQQAASVVEKLGDYLITCGY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : *:.: * * : : . * *:.: :: ::.** : :*: : : : : . : : .: ** ::* :::: * : . ... .*.*.:** ", "identical_positions": 17, "similar_positions": 42, "identity": "13.18%" }, { "cls_id": "homologset.agr.SGD:S000005649", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q641X2-1", "uniprot_id": "LEO1_RAT", "id": "Q641X2-1", "name": "RNA polymerase-associated protein LEO1", "aln": "---MADMEDLFGSEAESEA--------------ERKDSDSGSDSDSDQDNGASGSNASGSESDQDER-------GDSGQPSNKELFGDDSEEEGAPHHSGSDNHSEQSDNRSEASEERSDHEDNEPSDVDQHSGSEAHNDDDDDDDDEDDDDEGHRSDEGSHHSEAEGSEKAQSDDEKWDGEDKSDQSDDDEKLQNSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDDDRQQLSEEEKGNSDDERPAASDNDEEKQNSDDEDRPQVSDEEKMQNSDDERPQVSDEDRRHSDDEEEQDQKSESARGSDSEDEVLRMKRKNAIPSDSEVDSDTEVPKDNN-GTMDLFGGADDISSGSDGEDKPPTPGQPVD-ENGLPQDQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFED--EEMLDEEGRTRLKLKVENTIRWRMRRDEEGNEIKESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQ--AVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQK--IRILPMAGRDPECQRTEMIKKEEERLRASIRRESQQRRMREKQHQRG-LSASYLEPDRYDEEEEGEESVSLAAIKNRYKGG-----IREERARIYSSDSDEGS-----EEDKAQRLLKAKKLNSDEEGESSGKRKAEDDDK-ANKKHKKYVISDEEEEEDD-------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5XJE5-1", "uniprot_id": "LEO1_MOUSE", "id": "Q5XJE5-1", "name": "RNA polymerase-associated protein LEO1", "aln": "---MADMEDLFGSEAESEA--------------ERKDSESESDSDSDQDNGASGSNASGSESDQDDR-------GDSGQPSNKELFGDDSEEEGASHHSGSDNHSERSDNRSEASE-RSDHEDNEPSDEDQHSGSEAHNDD---------DDEGHRSDEGSRHSEAEGSEKAQSDDEKWDGEDKSDQSDD-EKLQNSDDEDREQGSDEDKLQNSDDDEEKMQNTDDEDRAQISDDDRQQLSEEEKGNSDDEHPVASDNDEEKQNSDDEDQPQVSDEEKMQNSDDERPQVSDEDGRRSDGEEEQDQKSESARGSDSEDEVLRLKRKNAIPSDSEADSDTEVPKDNN-GTMDLFGGADDISSGSDGEDKPPTPGQPVD-ENGLPQDQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFED--EEMLDEEGRTRLKLKVENTIRWRIRRDEEGNEIKESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQ--AVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQK--IRILPMAGRDPECQRTEMIKKEEERLRASIRRESQQRRMREKQHQRG-LSASYLEPDRYDEEEEGEESVSLAAIKNRYKGG-----IREERARIYSSDSDEGS-----EEDKAQRLLKAKKLNSDEEGESSGKRKAEDDDK-ANKKHKKYVISDEEEEEDD-------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WVC0-1", "uniprot_id": "LEO1_HUMAN", "id": "Q8WVC0-1", "name": "RNA polymerase-associated protein LEO1", "aln": "---MADMEDLFGSDADSEA--------------ERKDSDSGSDSDSDQENAASGSNASGSESDQDER-------GDSGQPSNKELFGDDSEDEGASHHSGSDNHSERSDNRSEASE-RSDHEDNDPSDVDQHSGSEAPNDD---------EDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDD-EKIQNSDDEERAQGSDEDKLQNSDDDE-KMQNTDDEERPQLSDDERQQLSEEEKANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDEEHRHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEADSDTEVPKDNS-GTMDLFGGADDISSGSDGEDKPPTPGQPVD-ENGLPQDQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFED--EEMLDEEGRTRLKLKVENTIRWRIRRDEEGNEIKESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQ--AVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQK--IRILPMAGRDPECQRTEMIKKEEERLRASIRRESQQRRMREKQHQRG-LSASYLEPDRYDEEEEGEESISLAAIKNRYKGG-----IREERARIYSSDSDEGS-----EEDKAQRLLKAKKLTSDEEGEPSGKRKAEDDDK-ANKKHKKYVISDEEEEDDD-------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYV9-1", "uniprot_id": "LEO1_DANRE", "id": "Q6NYV9-1", "name": "RNA polymerase-associated protein LEO1", "aln": "---MADMDELFGSDGDSDN--------------EQRDSGSGSGSDSDHERPRSASNASGSESAQSDRDHDDDEDEDGGKPSNKELFGDDSEDEHGSQHSGS-QHSGSRHSGSRHSG--SRHSGSRHSG-SQHSGSQS-------------ERSGNQSD-----------ATMHSDNEHSMSEAHRGEQDD------EDDDDRGHRSDVGSPASGAGSR-----RSDRGSGSPGSEAGSPRSEAGSGHSDPGTPHT-DGEGSGKDAHSGDEKWGGDGKSDQSEDEDKQQNSDDERERSDEEGER-QKSESIKGSDSEDDFTRKKKK-KIASDSDSDSDAETQGGKKPAANDLFGEADDISSDSD-AEKPLTPGQPLDADDGMEGDQPEEEPAPETRIEVEIPKVSTDLGSDLYFVKLPNFLSVEPRPFDPQYYEDEFED--EEMLDEEGRTRLKLKVENTIRWRSRRDEEGNEVKESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQ--AVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQK--IRILPMAGRDPESQRNEMIKKEEERLRASIRRESQQRRMREKQHQRG-LNAGYLEPDRYDEDEEGEESISLAAIKSKYKGGG---GLREERARIYSSDSDEGS-----DEDKAQRLMKAKRLDSDEEGENSGKRKAEEDEESASKKPKKYVISDEEDEDGDGERDGDRERGGDMDGDGDGDMEGDGDVDRDGDMDGDGEGDGEGDGEEDE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94546-1", "uniprot_id": "ATU_DROME", "id": "Q94546-1", "name": "Another transcription unit protein", "aln": "-MGSQNSDDDSGSSGSSRSGSRSVTPQGGSAPGSQRSRRSGSGSDRSRSGSRSSRSRSGSGSPRSAR-------SGSAESRHSQLSGSARSKRSRSAHSRRSGSARSRKSGTPESPQSHRSGSLQSRKSGSPQSRRSGSPQSRKSGSTHSRRSGSAHSRRSGSARSRKSGSAQSDRSESRSRSHSGSLKG-------NEESRSNSPNLQIDVERANSKSGSRSRSRSRSGSRTSRSRSKTGTPSPNRSRSGSASGSGSDVGVPKKKARKASGSDQEKKKSGSDSDIEESPTKAKKSRLIDTDSDSNQDVGKKAPAAADIFGDADDISDDEDEAGPAARKSPVRSK-SRSQSKSHSHSRSMSHSRSRSRSRSRDKVESQVESAPKEDEPEPLPETRIDVEIPRISADLGKEQHFIKLPNFLSVVTHPFDPETYEDEIDE--EETMDEEGRQRIKLKVSNTIRWREYMNNKGDMVRESNARFVRWSDGSMSLHLGNEIFDAYRQPLLGDHNHLFVRQGTGLQGQ--SVFRTKLTFRPHSTESFTHKKMTMSLADRSSKTSG--IKILTQVGKDPTTDRPTQLREEEAKLRQAMRNQHKSLPKKKKPGAGEPLIGGGTSSYQHDEGSDDENAISLSAIKNRYKKGSGAGQAEVKASTIYSSDEDEGSDFEARRSKKVDKAKASKALRDSDSESDAGSAKSGHSNKSGGEGGSASGSENEGSQKSGGGSSKSASGSGSGSGSGSGSGSDND------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38439-1", "uniprot_id": "LEO1_YEAST", "id": "P38439-1", "name": "RNA polymerase-associated protein LEO1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSESPQDQPQK------------------------------------EQISNNVGVTTNSTSNEETSRSQDDNVKEVNGNDDTKEEEQEEDAELDDLFGDDNDDDDDDDVKKSETEKSDSDSDEDDEGENINHRSRHRESLG-------LDDDEAEEQAMYTRKFYGEDANNFSDQDETTHTFK----------------------EENVELVRHIIPSKANVNETASHNEIFYARIPNFLTIDPIPFDPPSFEAKVNERASNSASREDQLDDRLIDENTVRWRYSRDKDQHVFKESNTQIVQWSDGTYSLKVGEECTDILVNDTSNTFLTVSHDQQELIQCYEGGEIKKTLMFIPTSTNSKIHQKLSKAVIRRNQRQSK--GPGTYIVSMDPEVEKKELERKQSQILRDRRRRQLKEKEKQESP----------DAAFETGFRKQNSPTTYGASRRNEYEEDDFLVDDDEEEEAAFDDEEDDNEE---EEEEEDADEENASRLRNLKREGAAMYREEEEEEKDRSETKRRRVAVIEDDEDED-------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VDP7-1", "uniprot_id": "Q9VDP7_DROME", "id": "Q9VDP7-1", "name": "Another transcription unit protein", "aln": "MADPNLHDNQVIKDGESSES---------WPAFNRRSPNPSFSSVDQQGNKTKARRQHQSRSHSFHSTANSVPESQGPLESRSDLNAKTSSKSERPYISTSNSSWTSESSSGSPPDSGESSSFSTSSSLSSSLLCAPEPKSINWSNPKSSSNISNETTTSAGQVGGIPSFSESDDQGSVDSETVSNIRKS--------TSLIELKDNFNTIIDEDNNQQLSNEGNILSPGTVSISNFPSSNEVANGLIDEMEQDLLSKQHSTSTPINKSNTMEKELLPLQCSSFPPTSSEGNILKPRVNPVPLGPSSNTEYESNGKNYNIEKRLSQLRYSSDEKESDVLSYASSDSLDLNFDYGDNAKNQNGNGMNGEVNGDKESQVLDIEEQRKPFEKDVAVKFQTTITTQNCGLLKGPSQFLKMPYFIPVESKAYVPETFQDRMTK--NDLKDEQSREDFINRLKATVRWR----ENENKTKESNAKIVRWSDGSETFHVGNEVFDMMHHPVTVNQNHLYVRLGSFYQPQ--GLIQNKLTVRPMLDSNFGQSHVQALRNRATNKPQSGCVKVITNMGSNPEHDHDRRMKEELSKLRQEGREKNRALMKNHPP-----------KRDRHYQGSDHNVAKNAGAFEEDDGEG-----ADCETSSALEVTNEPMRS----EEDTEDHMDDDASWSSPNSQEEGKQSSSEDDLPIGGAIRKPTRLVYSGSDSD--------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . : . : . .. . . . . : ... : . . . : ::* *:.: . .: * :: .. . .: ..:.: . *:*** :. . :***:::*:****: ::::*:* * : * . ::..* . * .. : :: .: . . :* :: ::: ** *.: : .. . .: . : .: .. . : . .: .. . . . . .. . . .:. ", "identical_positions": 25, "similar_positions": 114, "identity": "3.24%" }, { "cls_id": "homologset.agr.SGD:S000005650", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5I043-1", "uniprot_id": "UBP28_MOUSE", "id": "Q5I043-1", "name": "Ubiquitin carboxyl-terminal hydrolase 28", "aln": "MTAELQQDDSAGAADGHGSSCQMLLNQLREITGIQDPSFLHEALK--ASNGDITQAVSLLTDQRVKEPSHDTTAAEPS-----EVEESATSKDLLAKVIDLTHDNKDDLQAAIALS----------------------------------------LLES------PNIQADNRDLNRAHEANSAETK-RSKRKRCEV----WGENHNPNNWRRVDGWPVG------------LKNVGNTCWFSAVIQSLFQLPEFRRLVLSYNLPQNILENCRSHTEKRNIMFMQELQYLFALLLGSN-----RKFVDPSAALD---------------LLKGAFRSSEEQQQDVSEFTHKLLDWLEDAFQLAVNVNSHLRNKSENPMVQLFYGTFLTEGVREGKPFCNNETFGQYPLQVNGYHNLDECLEGAMVEGDIALLPS-DRSVKYGQERWFTKLPPVLTFELSRFEFN-QSLGQPEKIHNKLEFPQIIYMDRYMYKSKELIRS-KRESVRKLKEEIQVLQQKLERYVKYGSGPSRFPLPDMLKYVIEFASTKPASESCLSGSAEHVTLPLPSV--------HCPISDLTPKESSSPESCSQNAGSTFSSPEDALPSSEGMNGPFTSPHSSLETPAPP-APRTVTDEEMNFVKTCLQRWRSEIEQDIQDLKNCISSSTKAIEQMYCDPLLRQVPYRLHAVLVHEG---QASAGHYWAYIYNQPRQTWLKYNDIS----------VTESSWEELERDSYGGLRNVSAYCLMYINDNLPHFSAEASSNESDETAGEVEALSVELR--QYIQEDNWRFQQEVEEWEEE------------------------------------------------QSCKIPQMES-----------SPNSS----------------------SQDFST-------------------------SQESPAVSSHEVRCLSSEHAVIAKEQTAQAIANTAHAYEKSGVEAALS------------------------------------------------------------------------------------------EAFHEEY-SRLYQLAKETPTSHSDPRLQHVLVYFFQNEAPKRVVERTLLEQFADRNLSYDERSISIMKVAQAKLMEIGPDDMN-----------MEEYKRWHEDYSLFRKVSVYLLTGLELFQKGKYQEALSYLVYAYQSNAGLLVKGPRRGVKESVIALYRRKCLLELNAKAASLFETNDDHSVTEG---INVMNELIIPCIHLIINNDISKDDLDAIEVMRNHWCSYLGKDIAENLQLCLGEFLPRLLDPSAEIIVLKEPPTIRPNSPYDLCNRFAAVMESIQGVSTVTVK----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZJ96-1", "uniprot_id": "UBP28_RAT", "id": "D3ZJ96-1", "name": "Ubiquitin carboxyl-terminal hydrolase 28", "aln": "MTAELQQDDAAGAADGHGSSCQMLLNQLREITGIQDPSFLHEALK--ASNGDITQAVSLLTDQRVKEPSHDTAATEPS-----EVEESATSKDLLAKVIDLTHDNKDDLQAAIALS----------------------------------------LLES------PNIQTDSRDLNRIHEANSAETK-RSKRKRCEV----WGENHNPNNWRRVDGWPVG------------LKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNILENCRSHTEKRNIMFMQELQYLFALLLGSN-----RKFVDPSAALD---------------LLKGAFRSSEEQQQDVSEFTHKLLDWLEDAFQLAVNVNSNPRTKSENPMVQLFYGTFLTEGVREGKPFCNNETFGQYPLQVNGYHNLDECLEGAMVEGDIALLPS-DRSVKYGQERWFTKLPPVLTFELSRFEFN-QSLGQPEKIHNKLEFPQVIYMDRYMYKSKELIRS-KRESIRKLKEEIQVLQQKLERYVKYGSGPSRFPLPDMLKYVIEFASTKPASESCLSGSVEHMTLPLPSV--------HCPISDLTAKESSSPKSCSQNAEGSFSSPEDALPNSEVMNGPFTSPHSSLEMPAPPPAPRTVTDEEMNFVKTCLQRWRSEIEQDIQDLKNCISSTTQAIEQMYCDPLLRQVPYRLHAVLVHEG---QASAGHYWAYIYNQPRQIWLKYNDIS----------VTESSWEELERDSYGGLRNVSAYCLMYINDKLPHCSAEAAHGESDQTA-EVEALSVELR--QYIQEDNWRFEQEVEEWEEE------------------------------------------------QSCKIPQMES-----------SPNSS----------------------SQDFST-------------------------SQESSAASSHGVRCLSSEHAVIAKEQTAQAIANTAHAYEKSGVEAALSE----------------------------------------------------------VMLSPAMQGVLLAIAKARQTFDRDGSEAGLIKAFHEEY-SRLYQLAKETPTSHSDPRLQHVLVYFFQNEAPKRVVERTLLEQFADRNLSYDERSISIMKVAQAKLMEIGPEDMN-----------MEEYKRWHEDYSLFRKVSVYLLTGLELFQKGKYQEALSYLVYAYQSNAGLLVKGPRRGVKESVIALYRRKCLLELNAKAASLFETNDDHSVTEG---INVMNELIIPCIHLIINNDISKDDLDAIEVMRNHWCSYLGKDIAENLQLCLGEFLPRLLDPSAEIIVLKEPPTIRPNSPYDLCSRFAAVMESIQGVSTVTVK----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96RU2-1", "uniprot_id": "UBP28_HUMAN", "id": "Q96RU2-1", "name": "Ubiquitin carboxyl-terminal hydrolase 28", "aln": "MTAELQQDDAAGAADGHGSSCQMLLNQLREITGIQDPSFLHEALK--ASNGDITQAVSLLTDERVKEPSQDTVATEPS-----EVEGSAANKEVLAKVIDLTHDNKDDLQAAIALS----------------------------------------LLES------PKIQADGRDLNRMHEATSAETK-RSKRKRCEV----WGENPNPNDWRRVDGWPVG------------LKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFMQELQYLFALMMGSN-----RKFVDPSAALD---------------LLKGAFRSSEEQQQDVSEFTHKLLDWLEDAFQLAVNVNS-PRNKSENPMVQLFYGTFLTEGVREGKPFCNNETFGQYPLQVNGYRNLDECLEGAMVEGDVELLPS-DHSVKYGQERWFTKLPPVLTFELSRFEFN-QSLGQPEKIHNKLEFPQIIYMDRYMYRSKELIRN-KRECIRKLKEEIKILQQKLERYVKYGSGPARFPLPDMLKYVIEFASTKPASESCPPESDTHMTLPLSSV--------HCSVSDQTSKESTSTESSSQDVESTFSSPEDSLPKSK----PLTSSRSSMEMPSQP-APRTVTDEEINFVKTCLQRWRSEIEQDIQDLKTCIASTTQTIEQMYCDPLLRQVPYRLHAVLVHEG---QANAGHYWAYIYNQPRQSWLKYNDIS----------VTESSWEEVERDSYGGLRNVSAYCLMYINDKLPYFNAEAAPTESDQMS-EVEALSVELK--HYIQEDNWRFEQEVEEWEEE------------------------------------------------QSCKIPQMES-----------STNSS----------------------SQDYST-------------------------SQEPSVASSHGVRCLSSEHAVIVKEQTAQAIANTARAYEKSGVEAALSE----------------------------------------------------------VMLSPAMQGVILAIAKARQTFDRDGSEAGLIKAFHEEY-SRLYQLAKETPTSHSDPRLQHVLVYFFQNEAPKRVVERTLLEQFADKNLSYDERSISIMKVAQAKLKEIGPDDMN-----------MEEYKKWHEDYSLFRKVSVYLLTGLELYQKGKYQEALSYLVYAYQSNAALLMKGPRRGVKESVIALYRRKCLLELNAKAASLFETNDDHSVTEG---INVMNELIIPCIHLIINNDISKDDLDAIEVMRNHWCSYLGQDIAENLQLCLGEFLPRLLDPSAEIIVLKEPPTIRPNSPYDLCSRFAAVMESIQGVSTVTVK----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QHC1-1", "uniprot_id": "A0A8M1QHC1_DANRE", "id": "A0A8M1QHC1-1", "name": "ubiquitinyl hydrolase 1", "aln": "MRVEQEFEHGETSEN----SSQMLLNQLREITGIQDLQVLQSALN--AGQGDISHAIGLLTTQPPEEEHMPEQTTTAN-----NEKNTSSAQNGPA---------KDDLQTAIELS----------------------------------------LQES------QQAEAERRELHRALEVSAEENAARIKRKRCEG----SGESCSPAEWIRQEDCPVG------------IRNVGNTCWFSAVIQSLFHLPVFRRLVLNYCLSERVLEKCKSHSEKRNIAFMQELRCLFALMVGSN-----RRFVDPSAAVE---------------LLRDAFRTS-EAQQDVSEFTHKLLDWLEDAFQLAANGTN-PEDKQNNPMVQLFYGTFVAERLHEGEIVSNIEQFGQYPLQVNGFNNLDECLEGAMVEGEIESLHS-DQTLSSGQERWFSKLPPVLTFELSRFEFN-QSLGRPEKIHKKLEFPQVIYMDRYLHKNVNQTHG-RRGEVKRLKDQLTLLQQKLEGYKNYGSGPAKYPLADMLQYVLEFATTKPTNPGS----------PVPTN--------PPISTDPSSGDSSQTEADDAGSSDGSGCPPTATQRTP-IHKPFTQCRPPMEVPVQP-APHSVSEEELHFIRSCLQRWRAEVENTISELKASIDKVSQALEGMYSDNSLCQVPYRLHAVLVHEG---QASAGHYWAYIYDHAQRRWLKYNDVL----------VAESTWEELVRDSYGGMTNASAYCLMYINDNLPYLIAEDTDVETGQVLKGMDSLPSVLR--RYVREDNRWFQQELREWEEQFCQAQRDETPVQTNTSTSTEQPVPEEPQNPEPEPTQEQTNEDTEEPPSDSTPAPVQESEEPTVSPLNPISPEASENEEQINGSQTQDQPEEEKPDQSQSVSAGELETETEVEEQVTSPEGGAEAEVDAQTDPEASSTEESTAEDTNTQPENEVSEVEIPNVGKILVRSDVDGYNEE----------------------------------------------------------MMLTPAMQGVIFAIAKAREAFDKDGPEAGLIKAFHEEY-LRLYELSQEETTPQQDPRLQHVLVYLFQNKAPERVIERTLLEQFGDRNLSFDDRAVSIMREARSKLRLIRPEDMD-----------MDEYLQWHDDYSMFKTVFAYLLTGLEQYQNGKIREALIYLAHAHQDNSALLTKGERKGVDQSLIALYRRKCLKELNEKAATLFKSQDESDVTEG---ESLMNECVIPCMHLMVRDSVSQEDLDVIELIRNCWCSYLGQDMDDSLQEKLSEFLPRVLDCSAERVVLKEPPKVR-KSPHDLCSRLAAVMESIHSASVVIVK----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P57080-1", "uniprot_id": "UBP25_MOUSE", "id": "P57080-1", "name": "Ubiquitin carboxyl-terminal hydrolase 25", "aln": "MTVEQN----VLQQSAAQKHQQTFLNQLREITGINDAQILQQALK--DSNGNLELAVAFLTAKNAKTPPQEETGYYQT-ALPGNDRYISVGSQADANVIDLTGDDKDDLQRAIALS----------------------------------------LAESNRAFRETGITDEEQAISRVLEASIAENKACLKRTPIEV----WRDSRNPYDRKRQEKAPVG------------LKNVGNTCWFSAVIQSLFNLLEFRRLVLNYKPPSNAQDLPRNQKEHRNLPFMRELRYLFALLVGTK-----RKYVDPSRAVE---------------ILKDAFKSNDSQQQDVSEFTHKLLDWLEDAFQMKAEEET-DEEKPKNPMVELFYGRFLAMGVLEGKKFENTEMFGQYPLQVNGFKDLHECLEAAMIEGEIESLHS-DNSGKSGQEHWFTELPPVLTFELSRFEFN-QALGRPEKIHNKLEFPQVLYLDRYMHRNREITRI-KREEIKRLKDYLTVLQQRLERYLSYGSGPKRFPLVDVLQYALEFASSKPVCTSPVDDIDASS--SASGP--------LPSQSLPSTT-EQQGPCASDLPGSSSPASGAALPLRSVIHKPFTQSRIPPDLPMHP-APRHITEEELCVLESCLHRWRTEIENDTRDLQESISRIHRTIELMYSDKSMIQVPYRLHAVLVHEG---QANAGHYWAYIFDHRESRWMKYNDIA----------VTKSSWEELVRDSFGGYRNASAYCLMYIDDKAQFLIQEEFNKETGQALVGMETLPPDLR--DFVEEDNQRFEKELEEWDTQ-------------------------------------------------LAQRSLQEK--------LLAAPKLR----------------------EAEAS------------------------ATTAQAGG-ADYLEQPSRSDLSKHWKEETLRVIAKASHDLEDKGPETVLQS------------------------------------------------------------------------------------------AIKLEY-SRLVKLAQEDTPPETDYRLHHVLVYFIQNQAPKKIIEKTLLEQFGDRNLSFDERCHNIMKVAQAKLEMIKPEEVN-----------LEEYEEWHADYKKFRETTMYLITGLENFQRESYIDSLLFLLCAYQNNKELLSKGPYRGHDGELISHYRRECLLKLNEQAAELFESGEDGDVNNG---LIIMNEFIVPFLPLLLVDDMEEKDILAVEDMRNRWCSYLGQEMEANLQEKLTDFLPKLLDCSTEIKGFHEPPKLPSYSAHELCERFARIMLSLS--RTPADGR---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZPF8-1", "uniprot_id": "A0A8I5ZPF8_RAT", "id": "A0A8I5ZPF8-1", "name": "Ubiquitin carboxyl-terminal hydrolase 25", "aln": "MTVEQN----VLQQSAAQKHQQTFLNQLREITGINDAQILQQALK--DSNGNLELAVAFLTAKNAKTPPQEETAYYQTAALPGSDRYISVGSQADANVIDLTGDDKDDLQRAIALS----------------------------------------LAESNRTFRETGITDEEQAISRVLEASIAENKACLKRTPIEV----WRDSRNPYDRKRQDKAPVG------------LKNVGNTCWFSAVIQSLFNLLEFRRLVLNYKPPSNAQDLPRNQKEHRNLPFMRELRYLFALLVGTK-----RKYVDPSRAVE---------------ILKDAFKSNDSQQQDVSEFTHKLLDWLEDAFQMKAEEET-DEEKPKNPMVELFYGRFLAMGVLEGKKFENTEMFGQYPLQVNGFKDLHECLEAAMIEGEIESLHS-DNSGKSGQEHWFTELPPVLTFELSRFEFN-QALGRPEKIHNKLEFPQVLYLDRYMHRNREITRI-KREEIKRLKDYLTVLQQRLERYLSYGSGPKRFPLVDVLQYALEFASSKPVCTSPVDDIDATS--STSGS--------TSSQSLPSTT-EQQGTPASDLP-SSSPASGAALSLRSVIHKPFTQSRIPPDLPMHP-APRHITEEELSVLESCLHRWRTEIENDTRDLQESISRIHRTIELMYSDKSMIQVPYRLHAVLVHEG---QANAGHYWAYIFDHRESRWMKYNDIA----------VTKSSWEELVRDSFGGYRNASAYCLMYINDKAQFLIQEEFNKETGQALVGMETLPPDLR--DFVEEDNQRFEKELEDWDTQ-------------------------------------------------LAQRALQEK--------LLAAQKLR----------------------EAESS------------------------APTAQAGG-PDYLEQPSRSDLSKHWKEETLRVIAKASHDHEDKGPETVLQSKP--------------------ENTTSQPPSKQQAVEVQIPHIGKFMIESKEGGYDDEIMMTPSMQGIIMAIGKSRSVYDRCGPEAGFFKAIKLEY-SRLVKLAQEDTPPETDYRLHHVLVYFIQNQAPKKIIEKTLLEQFGDRNLSFDERCHNIMKVAQAKLEMIKPEEVN-----------LEEYEEWHADYKKFRETTMYLIIGLENFQRESYIDSLLFLICAYQNNKELLSKGPYRGHDGDLISHYRRECLLKLNEQAAELFESGEDREVSNG---LIIMNEFIVPFLPLLLVDETEERDILAVEDMRNRWCSYLGQDMEPNLQEKLTDFLPKLLDCSTEIKGFHEPPKLPSYSAHELCERFARIMLSLS--RTPADGR---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UHP3-2", "uniprot_id": "UBP25_HUMAN", "id": "Q9UHP3-2", "name": "Ubiquitin carboxyl-terminal hydrolase 25", "aln": "MTVEQN----VLQQSAAQKHQQTFLNQLREITGINDTQILQQALK--DSNGNLELAVAFLTAKNAKTPQQEETTYYQT-ALPGNDRYISVGSQADTNVIDLTGDDKDDLQRAIALS----------------------------------------LAESNRAFRETGITDEEQAISRVLEASIAENKACLKRTPTEV----WRDSRNPYDRKRQDKAPVG------------LKNVGNTCWFSAVIQSLFNLLEFRRLVLNYKPPSNAQDLPRNQKEHRNLPFMRELRYLFALLVGTK-----RKYVDPSRAVE---------------ILKDAFKSNDSQQQDVSEFTHKLLDWLEDAFQMKAEEET-DEEKPKNPMVELFYGRFLAVGVLEGKKFENTEMFGQYPLQVNGFKDLHECLEAAMIEGEIESLHS-ENSGKSGQEHWFTELPPVLTFELSRFEFN-QALGRPEKIHNKLEFPQVLYLDRYMHRNREITRI-KREEIKRLKDYLTVLQQRLERYLSYGSGPKRFPLVDVLQYALEFASSKPVCTSPVDDIDASS--PPSGS--------IPSQTLPSTT-EQQGALSSELP-STSPSSVAAISSRSVIHKPFTQSRIPPDLPMHP-APRHITEEELSVLESCLHRWRTEIENDTRDLQESISRIHRTIELMYSDKSMIQVPYRLHAVLVHEG---QANAGHYWAYIFDHRESRWMKYNDIA----------VTKSSWEELVRDSFGGYRNASAYCLMYINDKAQFLIQEEFNKETGQPLVGIETLPPDLR--DFVEEDNQRFEKELEEWDAQ-------------------------------------------------LAQKALQEK--------LLASQKLR----------------------ESETS------------------------VTTAQAAGDPEYLEQPSRSDFSKHLKEETIQIITKASHEHEDKSPETVLQS------------------------------------------------------------------------------------------AIKLEY-ARLVKLAQEDTPPETDYRLHHVVVYFIQNQAPKKIIEKTLLEQFGDRNLSFDERCHNIMKVAQAKLEMIKPEEVN-----------LEEYEEWHQDYRKFRETTMYLIIGLENFQRESYIDSLLFLICAYQNNKELLSKGLYRGHDEELISHYRRECLLKLNEQAAELFESGEDREVNNG---LIIMNEFIVPFLPLLLVDEMEEKDILAVEDMRNRWCSYLGQEMEPHLQEKLTDFLPKLLDCSMEIKSFHEPPKLPSYSTHELCERFARIMLSLS--RTPADGR---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B6G9-1", "uniprot_id": "A0A8M3B6G9_DANRE", "id": "A0A8M3B6G9-1", "name": "Ubiquitin carboxyl-terminal hydrolase 25", "aln": "MTVEQN----VLQQHS-QKHQQTLLNQLREVTGTTDVQLLQQALQ--VSNGDLVEAVAFLTEKNAKVPQQDEATYYQT-AQITNDRYISVGSQADTNVIDLTGDDKDDLQRAIALS----------------------------------------LEESNRAFRETGITDEEQAISRVLEASIAENKASLKRTHTEV----WSDSPNPHERKRMENCPVG------------LKNVGNTCWFSAVIQSLFNLLEFQRLVLHYSPPARMQDLPRNQKEHRNLPFMQELRHLFSLLVGSK-----RKYVDPSGAVE---------------ILKDAFKSSESQQQDVSEFTHKLLDWLEDAFQIKAEEDR-EGEKPKNPMVELFYGRFLAVGVLEGKKFENTEMFGQYPLQVNGFKDLHECLEAAMIEGEIESLHSAENSAKSGQEHWFTELPPVLTFELSRFEFN-QALGRPEKIHNKLEFPSMLYMDRYMDRNREITRI-KREEIRRLKEHLTVLQQRLERYLSYGSGPKRFPLADVLQYAMEFASSKPVCTSPVEDIDTTA--PPGGT--------IAQLPPPASAGEQPDACVSAEGSGSGLQASQQQQQRVSIHKPFTQSRVPPDLPMHP-APRHITEEELRVLESCLHRWRSEVENDTRDLQASISRIHRTIELMYSDKSMMQVPYRLHAVLVHEG---QANAGHYWAYIYDRHHQRWMKYNDIA----------VTKSSWEELVRDSFGGYRNASAYCLMYIDDKKPFLIQEEFDKETGQMLSGLDKLPPDLK--VFVEADNKLFEREMEEWDAL-------------------------------------------------QARKLQQEK--------LALAAAAA----------------------AAAAASVAVQP-------MSTEPCSPDNTAPSAAPQHDPEYMEQQSPSGDSKHLQEDTERAISKAAAEHDEKSPEALLNTSQSSHPDSKLTSDPCPPPDPEQDDPTCPPPGPQRVVEVAIPNVGTFVIQSKEGGYDDEAMMTPNMQGIIMAIGKSRSVYDKCGPEAAFFKAMKVEY-TRLLRLAQEDTPPERDYRLQHVIVFFIHNEAPKKIVERTLLMQFADRNLGFDERCKSIMKVARAKLELIKPDEVN-----------MEEYEMWHQDYRIFRETSVFLLIGLELFMKKSFVEALMYLIYAYQYNKELLAKGPYRGHDEELIAHYRRECLLKLNEYAAALFETGEEAKVNTG---LSIMNDLVVPCLPLLLVDEMEEKDMVAVEDMRNRWCSYLGQEMEPNLQEKLTDFLPKLLDCSTEIKSFHEPPKLPSYSTLELFERFGRVMTSLTMGRTPADGR---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q01476-1", "uniprot_id": "UBP2_YEAST", "id": "Q01476-1", "name": "Ubiquitin carboxyl-terminal hydrolase 2", "aln": "MPNEDNELQKAIENHHNQLLNQDKENADRNGSVIEDLPLYGTSINQQSTPGDVDDGKHLLYPDIATNLPLKTSDRLLDDILCDTIFLNSTDPKVMQKGLQSRGILKESMLSYSTFRSSIRPNCLGSLTDQVVFQTKSEYDSISCPKYNKIHVFQAVIFNPSLAEQQISTFDDIVKIPIYHLKVSVKVRQELERLKKHVGVTQFHSLDHLHEYDRVDLSTFDSSDPNLLDYGIYVSDDTNKLILIEIFKPEFNSPEEHESFTADAIKKRYNAMCVKNESLDKSETPSQVDCFYTLFKIFKGPLTRKSKAEPTKTIDSGNLALNTHLNPEWLTSKYGFQASSEIDEETNEIFTEYVPPDMVDYVNDLETRKIRESFVRKCLQLIFWGQLSTSLLAPNSPLKNTKSVKGMSSLQTSFSTLPWFHLLGESRARILLNSNEQTHSPLDAEPHFINLSVSHYYTDRDIIRNYESLSSLDPENIGLYFDALTYIANRKGAYQLIAYCGKQDIIGQEALENALLMFKINPKECNISELNEATLLSIYKYETSNKSQVTSNHLTNLKNALRLLAKYTKSDKLKFYVDHEPYRALSQAYDTLSIDESVDEDIIKTAYSVKINDSPGLKLDCDRALYTIAISKRSLDLFNFLTEECPQFSNYYGPEKLDYQEALKLLQVNENASDETILKIFKQKWFDENVYEPDQFLILRAALTKISIERNSTLITNFLLTGTIDPNSLPPENWPTGINNIGNTCYLNSLLQYYFSIAPLRRYVLEYQKTVENFNDHLSNSGHIRRIGGREISRGEVERSIQFIYQLRNLFYAMVHTRERCVTPSK--------------------------------------ELAYLAFAPSNVEVEFEVEGNKVVDQTGVLS--------------------DSKKETTDDAFTTKIKDTSLIDLEMEDGLNGDVGTDANRKKNESNDAEVSENEDTTGLTSPTRVAKISSDQLENALEMGRQQ-----------------------------------------------------------DVTECIGNVLFQIESGSEPIRYDEDNEQYDLVKQLFYGTTKQSIVPLSATNKVRTKVERFLSLLINIGDHPKDIYDAFDSYFKDEYLTMEEYGDVIRTVAVTTFPTILQVQIQRVYYDRERLMPFKSIEPLPFKEVIYMDRYADTENPLLLAKKKETEEMKQKLKVMKNRQRELLSRDDSGLTRKDAFLESIKLLESDTIKKTPLKIEAANDVIKTLRNNVQNIDNELMKLYNDINSLEEKISHQFDDFKEYGYSLFSVFIHRGEASYGHYWIYIKDRNRNGIWRKYNDETISEVQEEEVFNFNEGNTATPYFLVYVKQGQEGDIEPLKRILK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * : * * *: : * . ::: *:: . :* . : . *:.: : : :. : : : :* . . : * : ... : : *. : :::. *: :. . . .: . : :: :::*: : : .:*: ::: : .*::. . :::..*: : : : : .: : :*:* : : : .. . * : . . ..: * . .. : . : . * * :*. : : * ::*. : : * * : *: . :: : : :* ::: * . .* .: :* . : . : . . . . . . ** . . : : :: *: .:: :: : : : *. . .*: .. : . : : * : :. *.: : :: : : : : . * * * . . . . : :: . * :. : . : : . . : :.: . . : . . : * : .. . ::.:.: ::: : : :: * *. * :: * * :.: * ::: :.. . : * . . : * : : ** :. . : : . :. ::: :: . : *: : : :. . :: .: * : : : : : . . . : . :: . : ", "identical_positions": 57, "similar_positions": 277, "identity": "4.1%" }, { "cls_id": "homologset.agr.SGD:S000005651", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63619-1", "uniprot_id": "COQ7_RAT", "id": "Q63619-1", "name": "NADPH-dependent 3-demethoxyubiquinone 3-hydroxylase, mitochondrial", "aln": "-MSGAG--AIAAASVGCLRTGVPRPFSAYGRGLIIRCHSTGMT-LDNINRAAVDQIIRVDHAGEYGANRIYAGQMAVLGR--TSVGPVIQKMWDQEKNHLKKFNELMVAFRVRPTVLMPLWNVAGFALGAGTALLGKEGAMACTVAVEESIAHHYNNQIRMLMEED-----------AEKYEELLQVIKQFRDEELEHHDTGLEHDAELAPAYTLLKRLIQAGCSAAIYLSERF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97478-1", "uniprot_id": "COQ7_MOUSE", "id": "P97478-1", "name": "NADPH-dependent 3-demethoxyubiquinone 3-hydroxylase, mitochondrial", "aln": "-MSAAG--AIAAASVGRLRTGVRRPFSEYGRGLIIRCHSSGMT-LDNINRAAVDRIIRVDHAGEYGANRIYAGQMAVLGR--TSVGPVIQKMWDQEKNHLKKFNELMIAFRVRPTVLMPLWNVAGFALGAGTALLGKEGAMACTVAVEESIANHYNNQIRMLMEED-----------PEKYEELLQVIKQFRDEELEHHDTGLDHDAELAPAYALLKRIIQAGCSAAIYLSERF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99807-1", "uniprot_id": "COQ7_HUMAN", "id": "Q99807-1", "name": "NADPH-dependent 3-demethoxyubiquinone 3-hydroxylase, mitochondrial", "aln": "-MSCAG--AAAAPRLWRLRPGARRSLSAYGRRTSVRFRSSGMT-LDNISRAAVDRIIRVDHAGEYGANRIYAGQMAVLGR--TSVGPVIQKMWDQEKDHLKKFNELMVTFRVRPTVLMPLWNVLGFALGAGTALLGKEGAMACTVAVEESIAHHYNNQIRTLMEED-----------PEKYEELLQLIKKFRDEELEHHDIGLDHDAELAPAYAVLKSIIQAGCRVAIYLSERL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3W4-1", "uniprot_id": "Q9W3W4_DROME", "id": "Q9W3W4-1", "name": "5-demethoxyubiquinone hydroxylase, mitochondrial", "aln": "-MNGMLRRGLSRPEPRLLSKRYLSSATGGGSAGTTEGGSSETTPLRPRPNALTDEIIRVDHAGELGADRIYAGQMAILGN--GPLGKTIGHMWEQEKEHRKQFEQLIQQHRVRPTIMTPIWNVAGFVLGAGTALMGEKAAMACTVAVETVIVEHYNDQLRQIMEA------------PNPDKELLATITKFRDEEQEHHDTGIDHGAEQAPFYQAMTEVIKFGCKTAIAISKKI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41735-1", "uniprot_id": "COQ7_YEAST", "id": "P41735-1", "name": "5-demethoxyubiquinone hydroxylase, mitochondrial", "aln": "MLSRVSVFKPASRGFSVLSSLKITEHTSAKHTEKPEHAPKCQN-LSDAQAAFLDRVIRVDQAGELGADYIYAGQYFVLAHRYPHLKPVLKHIWDQEIHHHNTFNNLQLKRRVRPSLLTPLWKAGAFAMGAGTALISPEAAMACTEAVETVIGGHYNGQLRNLANQFNLERTDGTKGPSEEIKSLTSTIQQFRDDELEHLDTAIKHDSYMAVPYTVITEGIKTICRVAIWSAERI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : * : . .. . * * *.:****:*** **: ***** :*.. : .: ::*:** .* : *::* ****::: *:*:. .*.:******:. :.***** *** * ***.*:* : : .: :.* * :***:* ** * .:.*.: * * :. *: * .** ::::", "identical_positions": 68, "similar_positions": 61, "identity": "29.06%" }, { "cls_id": "homologset.agr.SGD:S000005652", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DB29-1", "uniprot_id": "IAH1_MOUSE", "id": "Q9DB29-1", "name": "Isoamyl acetate-hydrolyzing esterase 1 homolog", "aln": "MSLCERAASGSALLWPRVLLFGDSITQFSFQQG---------GWGSLLADRLVRKCDVLNRGFSGYNTRWAKIILPRLIRKGPGMENPVAVTIFFGANDSSLKDENPKQHVPLDEYSANLRDMVQYLRSVDVPRERVILITPPPLCEAAWEKECVLKGCK-LNRLNSVVGEYANACLQVARDCGTDVLDLWTLMQK-DSQDFSSYLSDGLHLSPMGNEFLFLNLCPLLDKKVS-----SLPWLLPYWKDVEEAKPELSLLGDGDY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q711G3-1", "uniprot_id": "IAH1_RAT", "id": "Q711G3-1", "name": "Isoamyl acetate-hydrolyzing esterase 1 homolog", "aln": "MSLCELAASGSSLLWPRVLLFGDSITQFSFQQG---------GWGTLLADRLVRKCDVLNRGFSGYNTRWAKIILPRIIRKGAGLENPVAVTIFFGANDSTLKDENPKQHVPLDEYSANLRDMVQYLRSVDIPKERVILITPPPLCEAAWEKECILKGCK-LNRLNVAVGEYAKACLQVARDCGTDVLDLWTLMQK-DNQDFSSYLSDGLHLSPLGNEFLFFHLWPLLDKKVS-----SLPRLLPDWKDVEETKPELSLLGDGDH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2TAA2-1", "uniprot_id": "IAH1_HUMAN", "id": "Q2TAA2-1", "name": "Isoamyl acetate-hydrolyzing esterase 1 homolog", "aln": "MALCEAAGCGSALLWPRLLLFGDSITQFSFQQG---------GWGASLADRLVRKCDVLNRGFSGYNTRWAKIILPRLIRKGNSLDIPVAVTIFFGANDSALKDENPKQHIPLEEYAANLKSMVQYLKSVDIPENRVILITPTPLCETAWEEQCIIQGCK-LNRLNSVVGEYANACLQVAQDCGTDVLDLWTLMQ--DSQDFSSYLSDGLHLSPKGNEFLFSHLWPLIEKKVS-----SLPLLLPYWRDVAEAKPELSLLGDGDH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q503L4-1", "uniprot_id": "IAH1_DANRE", "id": "Q503L4-1", "name": "Isoamyl acetate-hydrolyzing esterase 1 homolog", "aln": "MSALKR------VIWPQIILFGDSITQFAFQAN---------GWGSELCHKLERKCDVINRGLSGYNTRWAKIVLPRIVPVSDAPIS--AVTVFFGANDCALEDKNPTQHVPLQEFSENLKDIVRFLVSKGVSNDNIIFITPPPLLEADWEKECLLKGSP-LNRLNSVAGQYAQACVQAAGESGVDVLDLWTLMQK-DGQDFSVYLSDGLHLSDKGNQFVAEHLWTLLERRVS-----DLPFILPYWGDVDPKCPESSLLCD---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41734-1", "uniprot_id": "IAH1_YEAST", "id": "P41734-1", "name": "Isoamyl acetate-hydrolyzing esterase", "aln": "------------MDYEKFLLFGDSITEFAFNTRPIEDGKDQYALGAALVNEYTRKMDILQRGFKGYTSRWALKILPEILKHES---NIVMATIFLGANDACSAG---PQSVPLPEFIDNIRQMVSLMKSYHIRP---IIIGPGLVDREKWEKEKSEEIALGYFRTNENFAIYSDALAKLANEEKVPFVALNKAFQQEGGDAWQQLLTDGLHFSGKGYKIFHDELLKVIETFYPQYHPKNMQYKLKDWRDVLDDGSNIMS------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :.:*******:*:*: . *: * .. ** *:::**:.**.:*** :**.:: .*:*:****. . * :** *: *::.:* : * : *:* * : . **:: : . * * . *:.* : * : . .: * . :* ..: :. *:****:* * ::. .* ::: . .: * * ** .: ", "identical_positions": 60, "similar_positions": 72, "identity": "22.64%" }, { "cls_id": "homologset.agr.SGD:S000005653", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q811M1-1", "uniprot_id": "RHG15_MOUSE", "id": "Q811M1-1", "name": "Rho GTPase-activating protein 15", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKRTSCSVQTSTN-------------------CDNSLEILNSAHQA-------TGAVQMRIKNAN-----------------------------------------SHQDRQ--------------------------------------------------------------------------SQTKS-------------MILTDAG----------------------------------------------------------------------KVTEPISRHR-RNHSQHVLK---------------------------DVIPPLEHP------------------MVEKEGYLQKAKIADGGKKLR-KNWSTSWIVLSGRKIEFYKDSKQQALP---------------------------------------------NMKTRHNVESVDLCGAHIEWAK-EKSSRKSVFQITTVSGNEFLLQSDIDFLILDWFQAIKNAIDRLPKNPSCGS-------------LELFNLQRSSSSELPSHCHIDRKEQKPE--HRKSFMFRLHHS--ASDTSDKNRVKSRLKKFISRRPSLKTLQEKGLIKD-QIFGSHLHTVCEREHSTVPWFVKQCIEAVE--KRGLDVDGIYRVSGNLATIQKLRFIVN------------------QEEKLNLDDSQWEDIHVVTGALKMFFRELSEPLFPYSFFERFVEAIKKQDSNEKI---------------------ETMRSLVKRLPPPNHDTMKILFRHLTKIVAKASQNLMSTQSLGIVFGPTLLR-AENESGNVAVHMVYQNQIAEFMLTEYDKIFSSEED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYC5-1", "uniprot_id": "RHG15_RAT", "id": "Q6AYC5-1", "name": "Rho GTPase-activating protein 15", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKRTSCSVQTSTN-------------------CDNSLETLNSAHQA-------TGAVQMRIKNAN-----------------------------------------SHPDRQ--------------------------------------------------------------------------SQTKS-------------MILTDAG----------------------------------------------------------------------KVTEPISRHR-RNHSQHVLK---------------------------DVIPPLEHP------------------MVEKEGYLQKAKIADGGKKLR-KNWSTSWIVLSGRKLEFYKDPKQQALP---------------------------------------------NVKPRPNAESVDLCGAHIEWAAKDKSSKKSVFQITTASGNEFLLQSDIDFLILDWFHAIKNAIDRLPKNPSFGS-------------LELFSFQRSSSSEQPSHCHIDRKEQKPE--NRKSFMFRLHHS--VSDTSDKNRVKSRLKKFISRRPSLKTLQEKGIIKD-QIFGSHLHTVCEREHSTVPWFVKQCIEAVE--KRGLEVDGIYRVSGNLATIQKLRFIVN------------------QEEKLNLDDSQWEDIHVVTGALKMFFRELSEPLFPYSFFERFVEAIKKQDSDAKI---------------------ETMKSLVKSLPPPNHDTMKILFGHLTKIVAKAAQNLMSTQSLGIVFGPTLLR-AENESGNVAVHMVYQNQVAEFMLTEYDKIFSSEED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q53QZ3-1", "uniprot_id": "RHG15_HUMAN", "id": "Q53QZ3-1", "name": "Rho GTPase-activating protein 15", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQKSTN-------------------SDTSVETLNSTRQG-------TGAVQMRIKNAN-----------------------------------------SHHDRL--------------------------------------------------------------------------SQSKS-------------MILTDVG----------------------------------------------------------------------KVTEPISRHR-RNHSQHILK---------------------------DVIPPLEQL------------------MVEKEGYLQKAKIADGGKKLR-KNWSTSWIVLSSRRIEFYKESKQQALS---------------------------------------------NMKTGHKPESVDLCGAHIEWAK-EKSSRKNVFQITTVSGNEFLLQSDIDFIILDWFHAIKNAIDRLPKDSSCPSRN-----------LELFKIQRSSSTELLSHYDSDIKEQKPE--HRKSLMFRLHHS--ASDTSDKNRVKSRLKKFITRRPSLKTLQEKGLIKD-QIFGSHLHKVCERENSTVPWFVKQCIEAVE--KRGLDVDGIYRVSGNLATIQKLRFIVN------------------QEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAIKKQDNNTRI---------------------EAVKSLVQKLPPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTLLR-AENETGNMAIHMVYQNQIAELMLSEYSKIFGSEED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C0D4-1", "uniprot_id": "RHG12_MOUSE", "id": "Q8C0D4-1", "name": "Rho GTPase-activating protein 12", "aln": "--MAERSG----KITAG-------QAYIEVEYDYEYDAKD-RKIVIRQGERYLLVKKTNDDWWQVRPDEN---SKAFYVPAQYVKEVTRKALMPPVKQATGLPNNSMKTIQSMHLQRSTENVNKMP--ELSSFGKPSSSVQGTGLIR------------------DAN---QNFGSNYNSGQ-----------------TLNLSLDLTHNNGKFNSDSHSPKVSS------------QNRTRLFGHFPGPEFLDIEKTSFSQEQSCDS------------------------------------------------AGEGSERIQQDSESGDELSSS-------------------STEQMRATTPPNQGRPDSPVYANLQELKISQSAL------------------------PPLPGSPAIQVNGEWETHKDSSGRCYYYNRTTQERTW-----------------------KPPRWARDVSTSR-DFQSPGEQEPLSSEENYHSSCFSQSDSQCG---SPPRGWSEELDERGHTLYTSDYTKEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQ------------QQREIIKSRSLDRRLQEPIVLTK-WRHSTIVLDSNDK----------------DSPTTTKLCLPENESP--PTS--SKHQDPG-----QEKYGLLNVTKITENGKKVR-KNWLSSWAVLQGSSLLFTKTQGSS--TSW-----------------------------------------FGSNQ-SKPEFTVDLKGAVIEMASKDKSSKKNVFELKTRQGTELLIQSDNDAVINDWFKVLSSTIN-----------------------NQVAEADEAAEEETPDSPGVEKHDKEKD--QKELKKLRSMKG-SSMDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKD-QVFGSNLANLCQRENGTVPKFVKLCIEHVE--EHGLDVDGIYRVSGNLAVIQKLRFAVN------------------HDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQ-EPRQRV---------------------TAVKDLIRQLPKPNQDTMQILFRHLKRVIENGEKNRMTYQSIAIVFGPTLLK-PERETGNIAVHTVYQNQIVELILLELSTVFGR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZDI5-1", "uniprot_id": "D3ZDI5_RAT", "id": "D3ZDI5-1", "name": "Rho GTPase-activating protein 12", "aln": "--MAERSG----KIASG-------QVYIEVEYDYEYEAKD-RKIVIRQGERYLLVKKTNDDWWQVRLDEN---SKAFYVPAQYVKEVTRKALMPPVKQTTGLPNNSMKTTQSMHLQRSTENVNKMP--ELSSFGKPSSSVQGTGLIR------------------DAN---QNFGSNYNSGQ-----------------TLNLSLDLTHNNGKFNSDSHSPKVSS------------QNRTRLFGHFPGPEFLDIEKTSFSQEQSCDS------------------------------------------------AGEGSERTHQDSESGDELSSS-------------------STEQMRATTPPNQGRPDSPVYANLQELKISQSAL------------------------PPLPGSPAIQVNGEWETHKDSSGRCYYYNRTTQERTW-----------------------KPPRWARDVSTSR-DFQSPGEQEPLSSEENYHSSCFSQSDSQCG---SPPRGWSEELDERGHTLYTSDYTKEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQ------------QQREIIKSRSLDRRLQEPIVLTK-WRHSTIVLDSNDK----------------DSPTSTKLCLPENESP--PTS--TKHQDPG-----QEKYGLLNVTKITENGKKVR-KNWLSSWAVLQGSSLLFTKTQGSS--TSW-----------------------------------------FGSNQ-SKPEFTVDLKGAAIEMASKDKSSKKNVFELKTRQGTELLIQSDNDAVINDWFKVLSSTIN-----------------------NQVAEADEAAEEEAPDSPGVEKQDKEKD--QKELKKLRSMKG-SSMDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKD-QVFGSNLANLCQRENGTVPKFVKLCIEHVE--EHGLDVDGIYRVSGNLAVIQKLRFAVN------------------HDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQ-EPRQRV---------------------TAVKDLIRQLPKPNQDTMQILFRHLKRVIENGEKNRMTYQSIAIVFGPTLLK-PERETGNIAVHTVYQNQIVELILLELSTVFGR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IWW6-1", "uniprot_id": "RHG12_HUMAN", "id": "Q8IWW6-1", "name": "Rho GTPase-activating protein 12", "aln": "MKMADRSG----KIIPG-------QVYIEVEYDYEYEAKD-RKIVIKQGERYILVKKTNDDWWQVKPDEN---SKAFYVPAQYVKEVTRKALMPPVKQVAGLPNNSTKIMQSLHLQRSTENVNKLP--ELSSFGKPSSSVQGTGLIR------------------DAN---QNFGPSYNQGQ-----------------TVNLSLDLTHNNGKFNNDSHSPKVSS------------QNRTRSFGHFPGPEFLDVEKTSFSQEQSCDS------------------------------------------------AGEGSERIHQDSESGDELSSS-------------------STEQIRATTPPNQGRPDSPVYANLQELKISQSAL------------------------PPLPGSPAIQINGEWETHKDSSGRCYYYNRGTQERTW-----------------------KPPRWTRDASISKGDFQNPGDQELLSSEENYYSTSYSQSDSQCG---SPPRGWSEELDERGHTLYTSDYTNEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQ------------QQREIIKSRSLDRRLQEPIVLTK-WRHSTIVLDTNDK----------------ESPTASKPCFPENESS--PSS--PKHQDTASSPKDQEKYGLLNVTKIAENGKKVR-KNWLSSWAVLQGSSLLFTKTQGSS--TSW-----------------------------------------FGSNQ-SKPEFTVDLKGATIEMASKDKSSKKNVFELKTRQGTELLIQSDNDTVINDWFKVLSSTIN-----------------------NQAVETDEGIEEEIPDSPGIEKHDKEKE--QKDPKKLRSFKV-SSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKD-QVFGSNLANLCQRENGTVPKFVKLCIEHVE--EHGLDIDGIYRVSGNLAVIQKLRFAVN------------------HDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQ-EPRQRV---------------------AAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLK-PEKETGNIAVHTVYQNQIVELILLELSSIFGR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GV37-1", "uniprot_id": "A0AC58GV37_DANRE", "id": "A0AC58GV37-1", "name": "", "aln": "--MSERDGRCDLSIAPG-------QVYIEVEYDYEYKAKD-KLISIRQGECYMLVRKTNEDWWQVRREEG---TKAFYVPAQYVREVRR-ALMPPPKPRAKPPN----VLEITHCRSSNENLNQRAPTEKSTFGRPPPSTTPSPLPG------------------QQTPPLLLRDSNHNPGMK----------------SVVAELTLLNNNNHHNFHHANPTLP-------------QGRAESPPRDQGCQGKLTGGLSVDTDGSVS-------------------------------------------------PGDGVEKMRNDSESGDELSSS-------------------STEHIQSVSLSGQGRPESPVYTNLQELKICQSSV------------------------PPVPSTSPLHVLGDWETHKDTSGRNFYFNRTTQERTW-----------------------KPPR-SRDNGVSRGDTSNTGDMEPLSSEENCPSTHSSQSDSQYG---SPPRGWSEELDEHGHTLYVSEYTNEKWIKHVDEQGRPYYYSADGSRSEWELPKYNLSPP------------ISGEAPKSHSLERKQQEPIVLTK-WRHSTYVLDISDKTTWFYLFA-------NKKLPFKNRWFSVNHPP--RGFGLPVYREPS------EKCGVLNVTKITEHGKKVR-KNWASTWTVLQGSSLLFAKGQGSG--TSWSYCHNGSFPELLLSLLSNWKRSIKPRPAVSYTHCRRARASSFGGNQ-SKPEFTVDLRGGSVEWASKEKSSKKHVIELKTRVGTELLIQSEIDSVINDWFRALSETIN-----------------------THAWESDEAIEEDMPESPGSEKHDKEKD--PRDSKKNRVVKN-SSMESSEQKKTRVKLKKFLTRRPTLQAVRDKGYIKD-QVFGCSLTALCQREGTSVPNFVKMCIEHVE--NTGLNVDGLYRVSGNLAVIQKLRFAVN------------------HDEKVNLDDSKWEDIHVTTGALKMLFRELPEPLFTYASFNDFVEAIKNSDYKQRV---------------------QSIKDLIKQLPKPNQETMKVLFKHLKRVIDHGEVNRMTTQSVAIVFGPTLLR-PEIETGNMAVHMVYQNQIVELILLEYENIFGR---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9QA49-1", "uniprot_id": "A0A8M9QA49_DANRE", "id": "A0A8M9QA49-1", "name": "", "aln": "--MADR------SIAPG-------QTYIEVEYDYDYKSKD-RLITIKHGESYLLVKKTNDDWWQVRKDDA---SKPFYVPAQYVREVRR-ALMPPPKPLNIAGRGGPAPNRPSALEIQRPNDNKKS---------PCPSPSSTALLP------------------PRD----DRGSPVSPTR-----------------HLPPAQMNTFPGSLPCFRAESPGSKL------------DGERD---KDKDSERKDRGEKAAVQEELAEE------------------------------------------------GGDS-DKNRIDSESGDELSSG-------------------STDNLQSLG-SGQGRPDSPVYTNLQEMKISQSST------------------------PPLPSSSPIHTNGDWETHKDQNGRHYYYNRSTQERTW-----------------------KPPR-ARDSLPRKEEKHDMTDTEVLSSEENCLS---SQSDSQYG---SPPRGWSEEMDEHGHTLYVCDYTNEKWLRHTDERGRLYYYSADGSRSEWELPKIGLKSQSNHT------PLMPGDLHKTRSLDRRLPDPIPISRTQRHSIYSHETNDKLKQKFVKVRQSFLPRRKTTLRSHPYFPQDTKTGSPDSDSSCPSSPKPPHSPSEKCATLNMTKITEHGKKVR-KNWTSYWTVLQGSLLIFNKGQGGG--SGW-----------------------------------------FGRDQKSSVEYSVDLKGGSVDWASKDKSSKKHVLELKTRQGTELLLQSDSDGLVNDWHKALTEAIH-----------------------TYMWESDEAIEEDMPESPENEKHDKEKD--RKNSKKARDIKKTASMDNAEQKK-KNKLVVLLLGRPTLQAVKDKGYIKD-QVFGCSLSSLCQRENSTVPRFVWLCIEQVE--KNGLGVDGLYRVSGNLAIIQKLRFAVN------------------HEEKIDLGDSKWEDIHVTTGALKMFFRELPEPLFTYTFFSDFISAIKMPDYKQKV---------------------QTVKDLMKKLPRPNHDTIQVLFKHLKKVIQHVDENRMTTQSVAIVFGPTLLR-PEIETANMAVHMVYQNQIVELILMEYDTIFGR---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B2D3-1", "uniprot_id": "A0A8M2B2D3_DANRE", "id": "A0A8M2B2D3-1", "name": "", "aln": "--MNPDPLFAPQHVWATMSL----SQQVLVNYEYTYTARDGRNVSIKPNEHYILVNKTNEEWWHVQKDAA---DKPFYIPAKYVTELPPETSQTPLDPPEEFSG--YESLQFGSQTADPAEVTLRVPDSIKRDTEKDGHRISTFIIPKEFFELKGLDPDPIKTEAEAGPPVSSNTSSPTNG-------------ETAFIILPPPVYTVNTTQSTETDTRSVDDP--------KDSVGRPRVDSSTIDEDIQMLNRAGWSEVLDVMGKEKNVYESLDTVREPES---PKDEADMTVNTTPVTPDAPMVEDD----TAVYVNIPRKRQTTINNSSPIASLLQD-----FPEPPENFLLDSAGWQVHTDDQSGQEFYYQPSTGRSTWENPLSSRSMESPVGTEGGRSPPSFPQSPACSPVAPAPRRWSSDWEKVLDESTGRHYFFNTVSGQSSWDPPE------DVDSPGRLMFLDDCPPPLPEEDYPASPELEEASPVSIPAEYSLIHVKKVSIPRVSLD--RSSPAGWSLDIDSEGTWTFTSEYTQEQWIKSLDDQGRTYYYLRDGSKSQWNLPEINPGQGGVAAQWLALLPYSKNVAGSSPGWYSASPGQYGVGNGASGEQDTVGSNWR----------------HSAGYPDDKNHSSYIQNTSDSEASSSPDTPHNVSNLEKAGILNKTKVSENGKKVR-KNWGHSWTVLHGGKLTFHKDPKSTPAG------------------------------------------ASSKTNQILPEFTVDLKGATINRAPKDKSSKKNVLELKTRTGAEYLIQYDTDSIIQDWHKVILDTIHQLN---------------------GDQHHSEEEDEVIDKSPTLDREERPFE--KRTMSTATRQPSTSSTSEAEQKKVRTKLKKFLLKRPTLQSVKDKGYIRE-NVFGCHLHNLCSQEKTRVPSFVEKCIRAVE--KRGLEIDGLYRVSGNLAVIQKLRFKAD------------------HED-LDLEEGNWD-IHVITGALKLFFRELQEPLFPYNLFNEFICAIKTPDYYSKI---------------------SHMRNLVRSLPPPNHDTMEALFSHLRRVIQHGNENRMTVQNVAIVFGPTLLK-PEEETASIATYMVFQNQIVEFLLSEFESIFHM---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B765-1", "uniprot_id": "A0ACD6B765_DANRE", "id": "A0ACD6B765-1", "name": "", "aln": "--MGETGKMTSVHTLG----------LVLVEFEYEYEGRDGHMVCIKPNERYILLAKTNDHWWHVCKDER---AKPFYIPAKYVKELPPN-IPSPLDYREPPGPDVKPAVPDLTETRKADEVTIRLRS--KGNYHKTENRMSTFGVPLDLHEPPSYKHGGPSDSLISLSSVSASDSSKQKKRMSHAPNLLFGSHSNLPTELVPDKFRVPSFSPADPLHRPIPAKPVEIPIIKNLNETKPHRTSPELESPIEPESESSSSEPMPSPDSE-NIYESISDLNIDLSSLTDKEPAGLPDTQTTTSSLPPSIKTDNDPTTALYANVADIKKNIPRSSNSSVSTCSSPGITLSPAPDSISPPSSAEWRVHTDHDSGKEFYYHPATGQSSWSDPRSP---QPGAGMESVTAP-----VPASSP--PSAR---SDWEQLLDEATGRHYYYNHASNKTSWTAPEPSAPASSKQGPHSQDKDKERPPPLPEEDYPKNQHEESHISFQLPKDFQLPQIKRAVIPRAVMDTNKDVPTGWTQSVGTDGKSVFTSELTHEQWIQSKDEKGKLYYYSKDGSKCQWTLPEALVPPGQPMNGNGVEQDGPPVLNNWRYTQFNISQEDLKFSPSHRRIASDNASDAS----------------SSGNSPESQHYDKKFRRRRN-LSSYSTDSHSHHSSLEKAGILNKTKVAENGKRLR-KNWAQSWTVLHDGVLTFHKDPKFAPAG------------------------------------------MSSKTNQIVPEYTVELKGATLSWASKEKSSKKNVLELKTRHGSEYLIQYDTDSIIQDWQKIILDTIKLLH---------------------EHGHNSEDEAEDVP-----EKSPLPAD--KEKKPEAARLSSTSS-IDTDQGRVRTKLRKFLQRRPTLQSVKEKGYIKE-NVFGCHLDTLCHRENTTVPKFVEKCIRSVE--KRGLKIDGIYRVSGNLAVIQKLRYKAD------------------HEEDLDLEDGQWEEIHVITGALKLFLRELPEPLFPFSFFDKFIAAIQISDYSQKV---------------------SYIRDLVRNLPLPNHDTMEVLFRHLRKVIEHGEMNRMSVQSTAIVFGPTLLR-PQEE-SNITMHMVFQNQIVELVLNEFNELFQTK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2AB59-1", "uniprot_id": "RHG27_MOUSE", "id": "A2AB59-1", "name": "Rho GTPase-activating protein 27", "aln": "---------MAADVEG--------DVYVLVEHPFEYTGKDGRRIAIQPNERYRLLRRSTEHWWHVRREPG---GRPFYLPAQYVRELPALGDPAPAPQPSVPQQR---PAVPEPLAYDYRFVSTP--VGADGSSAEPRGRASSLCGP-------------------ARQRTGGQRNSLAPG--------------GPACLYVRPAAPVRPAQSLDDLARGGTAPP------------AGLLGSAGHFKASSVAGSWVCPRPLAPSDSE-NVYEAIPDLRCPPRAESPKQVDDPPE--------------------PVYANVERQPRATSPRSAAAP------------------PRLSPVWETHTDTGTGRPYYYNPDTGVTTWESPFET--------PEGTTSP------ATSRASVGSGESLETEWGQYWDEESRRVFFYNPLTGETAWEDETEEL---EEDHQEQLEMQPSLSPRSPGQQRPPTPETDYPELLASYPEEDYSPVGSFSDPGPASP--LVAPPGWSCQITPDKQMLYTNQFTQEQWVRLEDQHGKPYFYNPEDSSVQWELPQVPIPAPR------------------------------------SVRKSSQDSDTP----------------AQASPPEE-----------------------KIKTLDKAGVLHRTKTVDKGKRLRKKHWSTSWTVLEGGVLTFFKDSKTSAAGG-----------------------------------------LRQPSKLSTPEYTVELKGASLSWAPKDKSSKKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAEGISELS---------------------ADLLQGEEGEPSSADFGSSERLGSWRE--EDVRQNAASPSLSPGGLESDLSRVRHKLRKFLQRRPTLQSLRDKGYIKD-QVFGCALAQLCERERSPVPRFVQQCIRTVE--ARGLDIDGLYRISGNLATIQKLRYKVD------------------HDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFHQFIAAIKLQDPAQRS---------------------RCVRDLVRTLPAPNQDTLRLLIQHLCRVIEHGEQNRMTVQNVAIVFGPTLLR-PEMEEASMPMTMVFQNQVVELILHQCADIFPPH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6TLK4-1", "uniprot_id": "RHG27_RAT", "id": "Q6TLK4-1", "name": "Rho GTPase-activating protein 27", "aln": "---------MAADVEG--------DVYVLVEHPFEYTGKDGRLIAIQPNERCRLLRRSTEHWWHVRREPG---GRPFYLPAQYVRELPALGDPVPAPQPSVLQQR---PTVPEPLAYDYRFVSTP--VGADGSSAEPRGRASSLCGP-------------------ARQRTSGQRNSLAPG--------------GPACLYLRPAAPVRPAQSLDDLARGGTAPP------------AGLLGSAGHFKASSVAGSWVCPRPLARSDSE-NVYEAIPDLRCPPRAKSPKQVDEPPE--------------------PVYANVERQPQVTSPRSAAAP------------------PRLSPVWETHTDAGTGRPYYYNPDTGVTTWESPFEA--------PEGATSP------TTSRASVGSGESLETEWGQYWDEESGRVFFYNPLTGETVWEDETEEL---EDDPEEQLEMQPSLSPRSPGQQRPPTPETDYPELLTSYPEEDYSPVGSFSDLGPTSP--LVAPPGWSCQITPEKQMLYTNQFTQEQWVRLEDQEGKPYFYNPEDSSVQWELPQVPVPAPR------------------------------------SGRKSSQDSDTP----------------AQASPPEE-----------------------KIKTLDKAGVLHRTKTVDKGKRLRKKHWNASWTVLEGGVLTFFKDSKTSAASG-----------------------------------------LRQPSKLSTPEYTVELRGASLSWAPKDKSSKKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAEGIEELS---------------------ADLPQREEGEPSSADFGSSERLGSWKE--EDVRPNAASPSLNPGSQESDLSRVRHKLRKFLQRRPTLQSLREKGYIKD-QVFGCALAQLCERERSPVPRFVQQCIRTVE--ARGLDIDGLYRISGNLATIQKLRYKVD------------------HDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFHQFIAAIKLQDPAQRS---------------------RCVRDLVRTLPAPNHDTLRLLIQHLCRVIEHGEQNRMSVQNVAIVFGPTLLR-PEMEEASMPMTMVFQNQVVELILHQCADIFPPH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZUM4-1", "uniprot_id": "RHG27_HUMAN", "id": "Q6ZUM4-1", "name": "Rho GTPase-activating protein 27", "aln": "---------MAADVVG--------DVYVLVEHPFEYTGKDGRRVAIRPNERYRLLRRSTEHWWHVRREPG---GRPFYLPAQYVRELPALGNPAAAAPP-GPHPS---PAAPEPLAYDYRFVSAAATAGPDGAPEESGGRASSLCGP-------------------AQRGAATQRSSLAPG--------------LPACLYLRPAAPVRPAQSLNDLACAAVSPP------------AGLLGSSGSFKACSVAGSWVCPRPLARSDSE-NVYEVIQDLHVPPPEESAEQVDDPPE--------------------PVYANIERQPRATSP-GAAAA------------------PLPSPVWETHTDAGTGRPYYYNPDTGVTTWESPFEA--------AEGAASP------ATSPASVDSHVSLETEWGQYWDEESRRVFFYNPLTGETAWEDEAEN------EPEEELEMQPGLSPGSPGDPRPPTPETDYPESLTSYPEEDYSPVGSFGEPGPTSP--LTTPPGWSCHVSQDKQMLYTNHFTQEQWVRLEDPHGKPYFYNPEDSSVRWELPQVPVPAPR------------------------------------SIHKSSQDGDTP----------------AQASPPEEK-VPAELDEVGSWEEVSPATAAVRTKTLDKAGVLHRTKTADKGKRLRKKHWSASWTVLEGGVLTFFKDSKTSAAGG-----------------------------------------LRQPSKFSTPEYTVELRGATLSWAPKDKSSRKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAQGIQELS---------------------AELPP-EESESSRVDFGSSERLGSWQEKEEDARPNAAAPALGPVGLESDLSKVRHKLRKFLQRRPTLQSLREKGYIKD-QVFGCALAALCERERSRVPRFVQQCIRAVE--ARGLDIDGLYRISGNLATIQKLRYKVD------------------HDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRS---------------------RCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLR-PEVEETSMPMTMVFQNQVVELILQQCADIFPPH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BRR9-1", "uniprot_id": "RHG09_HUMAN", "id": "Q9BRR9-1", "name": "Rho GTPase-activating protein 9", "aln": "-MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSDWWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELS-------------QALPSRAQASSEQPP-------------------------------------------------------PLPRKMCRSVSTDNLSPSLLKPFQ-----------EGPSGRSLSQEDLPSEASASTAGPQPLMSEP-----------------------------------------------PVYCNLVDLRRCPRSPPPGPACP---------------LLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRS-------------------------------------------------------------------------------------------------------------------------RSETNPG-----------SMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGS--------------------------------------------------LSLSQRTSQLDPP-----------------ALQAPRPLPQLLDDP-----------------HEVEKSGLLNMTKIAQGGRKLR-KNWGPSWVVLTGNSLVFYREPPPTAPSSG------------------------------------------WGPAGSRPESSVDLRGAALAHGR-HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQGSGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRD-QVFGCQLESLCQREGDTVPSFLRLCIAAVD--KRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCL---------------------SQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFR-PEQETSDPAAHALYPGQLVQLMLTNFTSLFP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91V57-1", "uniprot_id": "CHIN_MOUSE", "id": "Q91V57-1", "name": "N-chimaerin", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALTLFDTDEYRPPVWKSYLYQLQQEAP-----------------------------------------------------HPRRVTCTCEVENRPK------------------YYGREYHGMISREETDQLLSVAEGSYLIRESQRQP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GTYTLALRFG--------------------------------------------------------SQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAA---------------------------------------------------EYIAKMTINPIYEHIGYTTLNREPAYKQHMAVLKETHDEKEATGQDGVSEKRLTSLVRRAT------------------------------LKENEQIPKYEKVHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVK--KVYSCDLTTLVKAHITKRPMVVDMCIREIE--SRGLNSEGLYRVSGFSDLIEDVKMAFDR-----------------DGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQL---------------------ETLHEALRSLPPAHCETLRYLMAHLKRVTLHEKENLMSAENLGIVFGPTLMRSPELDPMAALNDIRYQRLVVELLIKNEDILF-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P39083-1", "uniprot_id": "RGA1_YEAST", "id": "P39083-1", "name": "Rho-type GTPase-activating protein 1", "aln": "MASTAPNEQFPSCVRCKEFITTGHAYELGCDRWHTHCFACYKCEKPLSCESDFLVLGTGALICFDCSDSCKNCGKKIDDLAIILSSSNEAYCSDCFKCCKCGENIADLRYAKTKRGLFCLSCHEKLLAKRKYYEEKKRRLKKNLPSLPTPVIDNGHTDEVSASAVLPEKTFSRPASLVNEIPSG----------SEPSKDIETNSSDIVPHFITGYNDSDDNSGSSKFGSNVSIDVIGPEENSTEHVNDDVKEEAEAPSANMSLNVATDPTLSCKEPPSHSRNLLNKTPLRNSSGQYLAKSPSSYRQGIIVNDSLEESDQIDPPNNSSRNASELLTS------------------VLHSPVSVNMKNPKGSNTDIFNTGEISQMDPSLSR--------------------KVLNNIVEETNALQRPVVEVVKEDRSVPDLAGVQQEQAEKYS-----------------------YSNNSGKGRKISRSLSRRSKDLMINLKSRATGKQDSNVKLSPASKVTSRRSQDLMRDNDSHTGLDTPNSNSTSLDILVNNQKSLNYKRFTDNGTLRVTSGKETALE-----------------------EQKNHSFKSPSPIDHLLQSPATPSN----------------VSMYRTPPLDSSLTFDRRNGSSYSNQNYSIPSWQKTPKTQLENSDNFEEQKETLYENSESRNDPSLDKEIVTAEHYLKQLKINLKELE--------------------------------------SQREELMKEITEMKSMKEALRRHIESYNSEKNKLYLDSNELSNNPPMINEISLGESPPVKHVATASSVARSSVKPKFWKFFSS------AKPQTEQSIQGVSTNNTNSIVKSAPVLLSAPSSGSNSGRLEISPPVLQNPNEFSDVRLVPIENDANMGQSKDGEEYLDGSNLYGSSLVARCNYENNEIPMILSVCIDFIESDEENMRSEGIYRKSGSQLVIEEIEKQFS--------------AWKVQQNTETPNILTEQDLNVVTGVLKRYLRKLPNPIFTFQIYEPLMRLVKSKKMMENLPFVGGKLSLEAKNSDTYMSSKSALKNILEDLPREHYRVLRVLSEHIEKVTRYSHWNRMTLYNLALVFAPGLIR--DFSGEKDIIDMKERNYIVAFIFGNYKDILT----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : : : : :. : .. : .: . : :::.. * . * .: ** :: .: :*:** ** ::.:. . . : ::: **.** :*.* *:.. : . ::. : :* : .:. * *: :: * *: . .:**.* *:: : . :. ::: : :: ", "identical_positions": 25, "similar_positions": 79, "identity": "2.12%" }, { "cls_id": "homologset.agr.SGD:S000005656", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVD5-1", "uniprot_id": "ORNT1_MOUSE", "id": "Q9WVD5-1", "name": "Mitochondrial ornithine transporter 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MKSNPA------IQAAIDLTAGAAGGTACVLTGQPFDTMKVKMQTFP-DLYRGLTDCCLKTYSQVG-FRGFYKGTSPALIANIAEN----SVLFMCYGFCQQVVRKVVGLDQQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAASQ--NTVWSVVKEIFRKDGPLGFYHGLS---STLLREVPGYFFFFGGYELSRSFFAS-----GRSKDELGPVPLMLSG--GFGGICLWLAVYPVDCIKSRIQVLSMTGKQTGLVRTFLSIVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMMNQLEAW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K309-1", "uniprot_id": "ORNT1_RAT", "id": "A0A0G2K309-1", "name": "Mitochondrial ornithine transporter 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MKSNPA------IQAAIDLTAGAAGGTACVLTGQPFDTMKVKMQTFP-DLYRGLTDCCLRTYSQVG-FRGFYKGTSPALIANIAEN----SVLFMCYGFCQQVVRKVVGLDRQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAASQ--NTVWSVVKEIFRKDGPLGFYHGLS---STLLREVPGYFFFFGGYELSRSFFAS-----GRSKDELGPIPLMLSG--GFGGICLWLAVYPVDCIKSRIQVLSMTGKQTGLIRTFLSIVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMMSQLEAC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y619-1", "uniprot_id": "ORNT1_HUMAN", "id": "Q9Y619-1", "name": "Mitochondrial ornithine transporter 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MKSNPA------IQAAIDLTAGAAGGTACVLTGQPFDTMKVKMQTFP-DLYRGLTDCCLKTYSQVG-FRGFYKGTSPALIANIAEN----SVLFMCYGFCQQVVRKVAGLDKQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAKSQ--NTVWSVIKSILRKDGPLGFYHGLS---STLLREVPGYFFFFGGYELSRSFFAS-----GRSKDELGPVPLMLSG--GVGGICLWLAVYPVDCIKSRIQVLSMSGKQAGFIRTFINVVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMMNQLEAY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BXI2-1", "uniprot_id": "ORNT2_HUMAN", "id": "Q9BXI2-1", "name": "Mitochondrial ornithine transporter 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MKSGPG------IQAAIDLTAGAAGGTACVLTGQPFDTIKVKMQTFP-DLYKGLTDCFLKTYAQVG-LRGFYKGTGPALMAYVAEN----SVLFMCYGFCQQFVRKVAGMDKQAKLSDLQTAAAGSFASAFAALALCPTELVKCRLQTMYEMEMSGKIAKSH--NTIWSVVKGILKKDGPLGFYHGLS---STLLQEVPGYFFFFGGYELSRSFFAS-----GRSKDELGPVHLMLSG--GVAGICLWLVVFPVDCIKSRIQVLSMYGKQAGFIGTLLSVVRNEGIVALYSGLKATMIRAIPANGALFVAYEYSRKMMMKQLEAY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T3T0-1", "uniprot_id": "A0AB32T3T0_DANRE", "id": "A0AB32T3T0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MAPHPV------TQAVIDLSAGACGGTACVISGQPFDTAKVKMQTFP-GLYRGFVHCFVSVYKQVG-LRGLYQGTTPALIANIAEN----AVLFMSYGFCQNVVRFLSGLDRNTELSDVQKACSGSVASVFSSLALCPTELVKCRLQAMHEMEASGKIASGQK-STVWSVVRNVLRTNGPLGFYQGFT---TTIVRELPGYFCFFGGYELSRSIFAHHM---ATDKEHIGVVPLMFSG--GFGGACLWLVVYPIDCVKSRIQVLSLAGKQEGFIKTLMGILRNEGVAPLYSGLTPTMIRTFPANGALFLAYEVSRKFMMKQFDH-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KVQ8-1", "uniprot_id": "Q7KVQ8_DROME", "id": "Q7KVQ8-1", "name": "Mitochondrial ornithine transporter 1", "aln": "MSECEQDTASAAAPTSNHNEDGDNEEAGSEAAEFVSLPPPLEPEPIKQRHPKSQPTDEAPPEPPPNEDEMPPPPPRIGSSQAGSSVLIMTPDEIIEAYERALQEGQEEDGETDGEKKKSGWLNRPISVKSTLRAVRDGLLFVVGGFLRFVRRLDMHGGGTGNNINFVEGLIDFLAGSLGGAAQVYVSQPLDTVKVKLQTFP-EAYRGMLDCFLSTYRKDGVLRGLYAGSVPAVFANVAEN----SVLFAAYGGCQKFVAFCVGKETAGDLTTVQNACAGSLAACFSTLTLCPTELIKCKLQALREMKNFVEPAHPQDIRTPWTLTRYIWRTEGIRGFYRGLS---STFLREMPGYFFFFGSYEGTRELLRRD----DQSKDDIGPLRTMIAG--AIGGVCLWTSTFPADVIKSRIQVKNLN---ESMFAVGADIVRREGVLALYRGLLPSVLRTIPATATLFVVYEYTKRALSATL---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12375-1", "uniprot_id": "ORT1_YEAST", "id": "Q12375-1", "name": "Mitochondrial ornithine transporter 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MEDSKKKG--LIEGAILDIINGSIAGACGKVIEFPFDTVKVRLQTQASNVFPTTWSCIKFTYQNEGIARGFFQGIASPLVGACLEN----ATLFVSYNQCSKFLEKHTNVSPLG-----QILISGGVAGSCASLVLTPVELVKCKLQVANLQVASAKTKHTK----VLPTIKAIITERGLAGLWQGQS---GTFIRESFGGVAWFATYEIVKKSLKDRHSLDDPKRDESKIWELLISG--GSAGLAFNASIFPADTVKSVMQTEHIS-----LTNAVKKIFGKFGLKGFYRGLGITLFRAVPANAAVFYIFETLSAL--------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A8I6G8E8-1", "uniprot_id": "A0A8I6G8E8_RAT", "id": "A0A8I6G8E8-1", "name": "Transcription initiation factor TFIID subunit 7", "aln": "-------------------------------------------------------------------------------------------------------MSKSKDDAPHELESQFILRLPPEYAATVRRAVQSG---------------HVNLKDRLSIELHPDGRHGIVRVDRVPLAAKLVDLPCVTESLKTIDKK-TFYKTADISQMLVATVDGDLYPPVEEPAATADPKANKKKDKDKEKKFVWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVKRLLSTDAEAVSTRWEIIAEDETKEAENQGLD-----------ISSPGMSGHRQGHDSLEHDELREIFNDLSSSSEDEEDVNIIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSSLQEELESLLEK--------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .: . * * .:: : . . * .. :: :. . : : .. * .* :. : : * * :* ::* . . . * . : ::. . : : . :. : : . . . * . * .:: * ", "identical_positions": 13, "similar_positions": 53, "identity": "2.71%" }, { "cls_id": "homologset.agr.SGD:S000005659", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05197-1", "uniprot_id": "EF2_RAT", "id": "P05197-1", "name": "Elongation factor 2", "aln": "MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYELSENDLNFIKQS----KDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGE---GQLGAAERAKKVEDMMKKLWGDRYFDPANGKFSKSANSPDGKKLPRTFCQLILDPIFKVFDAIMNFRKEETAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMYISKMVPTSDKGRFYAFGRVFSGVVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKARARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALDNFLDKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58252-1", "uniprot_id": "EF2_MOUSE", "id": "P58252-1", "name": "Elongation factor 2", "aln": "MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYELSENDLNFIKQS----KDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGE---GQLSAAERAKKVEDMMKKLWGDRYFDPANGKFSKSANSPDGKKLPRTFCQLILDPIFKVFDAIMNFRKEETAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMYISKMVPTSDKGRFYAFGRVFSGVVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKARARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALDNFLDKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13639-1", "uniprot_id": "EF2_HUMAN", "id": "P13639-1", "name": "Elongation factor 2", "aln": "MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYELSENDLNFIKQS----KDGAGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGE---GQLGPAERAKKVEDMMKKLWGDRYFDPANGKFSKSATSPEGKKLPRTFCQLILDPIFKVFDAIMNFKKEETAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMYISKMVPTSDKGRFYAFGRVFSGLVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKQRARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALDNFLDKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UVM4-1", "uniprot_id": "A0A8N7UVM4_DANRE", "id": "A0A8N7UVM4-1", "name": "Elongation factor 2", "aln": "MVNFTVDQIREIMDKKSNIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLYYELSENDSAFIKQC----KDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPDELFQTFQRIVENVNVIISTYGEGEHGPMGNIMVDPVIGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGDKKKGDLPPTERAKKVEEMMKKLWGDKYFDPSCGKFSKTANNADGKKLPRTFCQLVLDPIFKVFDAIMNFKKEETQKLIEKLEVKLDAEDKEKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQRYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMVPTTDKGRFYAFGRVFSGIVSTGQKVRIMGPNFTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFENSHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIVAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVSDESDQVCLSKSPNKHNRLYMKSRPFPDGLAEDIDKGDVSSRQELKLRARYLAEKYEWEVAEARKIWCFGPDGTGPNILVDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRAVRFDIHDVTLHADAIHRGGGQIIPTARRVLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPIFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPYDVNSKPSQIVADTRKRKGLKEGIPALDNFLDKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6P3J5-1", "uniprot_id": "EF2_DANRE", "id": "Q6P3J5-1", "name": "Elongation factor 2b", "aln": "MVNFTVDQIRAIMDKKSNIRNMSVIAHVDHGKSTLTDSLVSKAGIIASARAGETRFTDTRKDEQERCITIKSTAISMYYELTENDLAFIKQC----KDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEDEGGPMGNIMIDPVIGTVGFGSGLHGWAFTLKQFAEMYVAKFASKGE---AQLSPADRCKKVEDMMKKLWGDRYFDPAGGKFTKTANGPDGKKYPRTFAQLILDPIFKVFDAIMNFKKEETAKLIEKLDIKLDTEDKDKEGKPLLKAVMRRWLPAGEALLQMITIHLPSPVTAQKYRCELLYEGPGDDEAAMGIKNCDPKGPLMMYISKMVPTTDKGRFYAFGRVFSGVVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFDQAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVSAESDQMCLSKSPNKHNRLYMKARPFPDGLAEDIDKGDVSSRQELKTRARYLADKYEWEVTEARKIWCFGPDGTGPNMLVDVTKGVQYLNEIKDSVVAGFQWATKEGALCEENMRAVRFDIHDVTLHTDAIHRGGGQIIPTARRVLYACQLTAEPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVMGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPKDAASKPCQIVADTRKRKGLKEGIPALDNFLDKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13060-1", "uniprot_id": "EF2_DROME", "id": "P13060-1", "name": "Eukaryotic translation elongation factor 2", "aln": "MVNFTVDEIRGLMDKKRNIRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGETRFTDTRKDEQERCITIKSTAISMYFEVEEKDLVFITHPDQREKECKGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPILFMNKMDRALLELQLDAEELYQTFQRIVENVNVIIATYND-DGGPMGEVRVDPSKGSVGFGSGLHGWAFTLKQFSEMYSEKFK----------------IDVVKLMNRLWGENFFNAKTKKWQKQKE-ADNK---RSFCMYILDPIYKVFDAIMNYKKEEIGTLLEKIGVTLKHEDKDKDGKALLKTVMRTWLPAGEALLQMIAIHLPSPVVAQKYRMEMLYEGPHDDEAAIAVKSCDPDGPLMMYISKMVPTSDKGRFYAFGRVFAGKVATGQKCRIMGPNYTPGKKEDLYEKAIQRTILMMGRYVEAIEDVPSGNICGLVGVDQFLVKTGTITTFKDAHNMKVMKFSVSPVVRVAVEPKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVSEESDQMCLSKSPNKHNRLLMKALPMPDGLPEDIDNGDVSAKDEFKARARYLSEKYDYDVTEARKIWCFGPDGTGPNFILDCTKSVQYLNEIKDSVVAGFQWASKEGILADENLRGVRFNIYDVTLHADAIHRGGGQIIPTTRRCLYAAAITAKPRLMEPVYLCEIQCPEVAVGGIYGVLNRRRGHVFEENQVVGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQVLPGDPSEPSSKPYAIVQDTRKRKGLKEGLPDLSQYLDKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32324-1", "uniprot_id": "EF2_YEAST", "id": "P32324-1", "name": "Elongation factor 2", "aln": "MVAFTVDQMRSLMDKVTNVRNMSVIAHVDHGKSTLTDSLVQRAGIISAAKAGEARFTDTRKDEQERGITIKSTAISLYSEMSDEDVKEIKQK----TDGNSFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDTIEGVCVQTETVLRQALGERIKPVVVINKVDRALLELQVSKEDLYQTFARTVESVNVIVSTYAD---EVLGDVQVYPARGTVAFGSGLHGWAFTIRQFATRYAKKFG----------------VDKAKMMDRLWGDSFFNPKTKKWTNKDTDAEGKPLERAFNMFILDPIFRLFTAIMNFKKDEIPVLLEKLEIVLKGDEKDLEGKALLKVVMRKFLPAADALLEMIVLHLPSPVTAQAYRAEQLYEGPADDANCIAIKNCDPKADLMLYVSKMVPTSDKGRFYAFGRVFAGTVKSGQKVRIQGPNYVPGKKDDLFIKAIQRVVLMMGRFVEPIDDCPAGNIIGLVGIDQFLLKTGTLTTSETAHNMKVMKFSVSPVVQVAVEVKNANDLPKLVEGLKRLSKSDPCVLTYMSESGEHIVAGTGELHLEICLQDLEHDHAGVPLKISPPVVAYRETVESESSQTALSKSPNKHNRIYLKAEPIDEEVSLAIENGIINPRDDFKARARIMADDYGWDVTDARKIWCFGPDGNGPNLVIDQTKAVQYLHEIKDSVVAAFQWATKEGPIFGEEMRSVRVNILDVTLHADAIHRGGGQIIPTMRRATYAGFLLADPKIQEPVFLVEIQCPEQAVGGIYSVLNKKRGQVVSEEQRPGTPLFTVKAYLPVNESFGFTGELRQATGGQAFPQMVFDHWSTLGSDPLDPTSKAGEIVLAARKRHGMKEEVPGWQEYYDKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ****::* :*** *:********************* :****:.*:***:************ *********:: *: ::* *.: .: .********************************* :.*************:.*****::.:**:********:. ::*:*** * **.****::** : :*:: : * *:*.***********::**: * ** . .:*.:***: :*:. *: : .:.* *:* :****:::* ****::*:* *:**: : *. ::*: :**.***.*** :***.:***:**.:******.** ** * ***** ** .:.:*.***.. **:*:******:************:* * :* * ** ***:.****:**: *.***.:*****:**.*:* *.*** ****:****:****:** . :***:**********:**** **. ************:**** * :.******:**:*********:***.*** :*:* * ***:*****. **. .**********: :*: *: : :. *::* :..::::* *** :::.* ::*::***********.***:: * **.****:********.****:*** : *::*.**.:: *****:************* ** ** : *.*:: **::* ****** .*****.***::**:*..*.* ***:*.**************.:**. ******** *****. * .** : *:. :* :***:*:** :* .:: ***", "identical_positions": 514, "similar_positions": 200, "identity": "59.42%" }, { "cls_id": "homologset.agr.SGD:S000005660", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZA46-1", "uniprot_id": "D3ZA46_RAT", "id": "D3ZA46-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSTETELTPAPEGRKRYS-----------DIFQSLDNLEISLGNVTFDPLAGDL---VLREDLEPDKTDTAAVETEENSEAS-WSNPSPEGPAPLTEEELDLRLIRTKGGVDAALEYAKAWSRYAKELLAWTDKRANYELEFAKNIMKIAEAGKGSILQQSQMPLQYIYTLFLEHDHSLG-ALAIDTVAQQKRDYYQPLAAKRMEIEKWRKEFKEQWLK----EQKRMSEAEQALRRSQLQYIQRREDLRARTQGSPEDPPLQ------ASPGSNKQQERRRRSREEAQAKAHEAEALYQACVREANTRQQDLETTKRRIVSHVRKLVLQGDEVLRRVTLGLFELRGAQAERGPRSFSALAECCVPFEPGQRYQEFVRSLQPGAPPPPSPAFCFQEFAP--------------------VVHSFPQDTKKKFSGPLPTRLEE-----GPSEPGPWEVASLGS--QGIP----GSDVDSVGGGSESRSLDSPTSSPGAGARRLVKASSTGTESS-DDFEERDP-----DLGDGMENGTG---------SPFRKWTLSTAAQTHRLRRLRGPAKCRECEAFMVSG-TECEECFLTCHKRCLETLLILCGHQRLPARMPLFGVDFLQLPRDFPEEVPFVVTRCTAEIEHRALGLQGIYRVSGSRVRVERLCQAFENGRALVELSGNSPHDITSVLKRFLQELTDPVVPFHFYDAFISLAKTLHADPGDD--------------PGTPSPSPEIIRSLKTLLVQLPDSNYSTLRHLVAHLFRVAARFKENKMSANNLGIVFGPTLLRPPDGPGATSASPVACLLDSGHQAQLVEFLIVHYEQIFGMDELPLTSEPLTQDPALAPALLESSPQHPALLVAQDSQPLTIASDSSPD-------------------------------------------------------------------------------------PKQHSALEKCPKVAPPELTALQSNRKEEEEEDTRD-----------------------------------------GAGDGSSHSPEDLLLVAQSRGHFSRQPVKYS----------------------------------------------------RGGVRPVTHQLSSLALVASKLCEETPITVSAVHRGSLRARGLGPAAASPEGGTLRRNPLPKHFEITQETARLLSKLDSEAVSRTSCCADPEPEESEEHL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PGG2-1", "uniprot_id": "GMIP_MOUSE", "id": "Q6PGG2-1", "name": "GEM-interacting protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSAETELTPAPEGRKRYS-----------DIFQSLDNLEISLGNVTFDPLAGDP---VRREDLEPDKADTATVVTEENSEASSWRDLSPEGPAPLTEEELDLRLIRTKGGVDAALEYAKAWSRYAKELLAWTDKRANYELEFAKSIMKLAEAGKVSILQQSQMPLQYIYTLFLEHDLSLG-ALALETVAQQKRDYYQPLAAKRMEIEKWRKEFKEQWLK----EQKRMNEAVQALRRSELQYIQRREDLRARSQGSPEDPPSQ------ASPGSNKQQERRRRSREEAQAKAHEAEALYQACVREANSRQQDLETTKRRIVSHVRKLVLQGDEVLRRVTLGLFELRGAQAERGPRSFSALAECCVPFEPGQRYQEFVRTLQPGAPPPPSPAFCFQEFTA--------------------VVHSFPQDTKKKFSGPLPPRLEEE----GSPEPGPWEVASLGS--QGIP----GSDVDSVGGGSESRSLDSPTSSPGAGARRLVKASSTGTESS-DDFEERDP-----DLGDGIENGVG---------SPFRKWTLSTAAQTHRLRRLRGPAKCRECEAFMVSG-TECEECFLTCHKRCLETLLILCGHRRLPARMSLFGVDFLQLPRDFPEEVPFVITRCTAEIEHRALGLQGIYRVSGSRVRVERLCQAFENGRALVELSGNSPHDITSVLKRFLQELTDPVVPFHLYDAFISLAKTLHADPGDD--------------PGTPNPSPEIIRSLKTLLVQLPDSNYSTLRHLVAHLFRVAARFEENKMSANNLGIVFGPTLLRPPDGPRATGASPVACLLDSGHQAQLVEFLIVHYEQIFGMDELPLASEPLTQDPGLAPACLESSPQHPASLLAQDTQPLTIALDSSPD-------------------------------------------------------------------------------------PKHHSALEKCPEVTPPELATLQRDQREEEVEDTRD-----------------------------------------GAGDGSSHCPEDLALGAQSRGHFSRQPVKYS----------------------------------------------------RGGVRPVTHQLSSLALVASKLCEETPVTVSAVHRGSLRVRGLGPAAACPEGSPLRRNPLPKHFEITQETARLLSKLNSDAVSRTTCCADPEPEESEEHL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P107-1", "uniprot_id": "GMIP_HUMAN", "id": "Q9P107-1", "name": "GEM-interacting protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAAEPGLPPGPEGRKRYS-----------DIFRSLDNLEISLGNVTLEMLAGDP---LLSEDPEPDKTPTATVTN----EASCWSGPSPEGPVPLTGEELDLRLIRTKGGVDAALEYAKTWSRYAKELLAWTEKRASYELEFAKSTMKIAEAGKVSIQQQSHMPLQYIYTLFLEHDLSLG-TLAMETVAQQKRDYYQPLAAKRTEIEKWRKEFKEQWMK----EQKRMNEAVQALRRAQLQYVQRSEDLRARSQGSPEDSAPQ------ASPGPSKQQERRRRSREEAQAKAQEAEALYQACVREANARQQDLEIAKQRIVSHVRKLVFQGDEVLRRVTLSLFGLRGAQAERGPRAFAALAECCAPFEPGQRYQEFVRALRPEAPPPPPPAFSFQEFLP--------------------SLNSSPLDIRKKLSGPLPPRLDE-----NSAEPGPWEDPGTGWRWQGTPGPTPGSDVDSVGGGSESRSLDSPTSSPGAGTRQLVKASSTGTESS-DDFEERDP-----DLGDGLENGLG---------SPFGKWTLSSAAQTHQLRRLRGPAKCRECEAFMVSG-TECEECFLTCHKRCLETLLILCGHRRLPARTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENGRALVELSGNSPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDD--------------PGTPSPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPPDGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIFGMDELPQATEPPPQDSSPAPGPLTTSSQPPPPHLDPDSQPPVLASDPGPD-------------------------------------------------------------------------------------PQHHSTLEQHPTATPTEIPTPQSDQREDVAEDTKD-----------------------------------------GGGEVSSQGPEDSLLGTQSRGHFSRQPVKYP----------------------------------------------------RGGVRPVTHQLSSLALVASKLCEETPITS--VPRGSLRGRGPSPAAASPEGSPLRRTPLPKHFEITQETARLLSKLDSEAVPRATCCPDVQPEEAEDHL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BHU6-1", "uniprot_id": "A0A8M2BHU6_DANRE", "id": "A0A8M2BHU6-1", "name": "", "aln": "--------------MLKRVSSNKSYSPYATSQ--------RVKKSSSKKKLDILPNKPNVWLKQLSALQEQPRKDAVDSVTSSSQTSSSLSPPIVEVSSSCPGTPLTQHSKALGCPSPMGTLKRPTSLSRNPSAAGFPIQS----WVFSKGAGK-SVIAQSPSPETADTTVAIEVEDIPSLLRSVERFAKAVEKLKDVVLEDKQEN--RRPLAHECLGEVLRVLRQVISMYPLLNTVETLTAAGKLISQVKGYHYESCIEPEK----KDFEKAIETIAVAFSSNVSELLMGEVDSSTLLSVVPTEKSRSMENLS----GHGSSHTWGDSSELAMSAEEVDIILQRSEGGVDSALTYAKTISKYLKDLIGYVERKLALELEFSKGLQRIYQSCKQTITQP-HMPFFTIYSQALEQDLEQSNGMHQAAATLQNQTFIMPLMVRKQEHEKKRKEIKEQWLK----AKRKLMECDVNLRRAKQVYMTRCEEYDKARTAANRAEEE-------GGSATTKTLDKKKRLEEEARNKAEEAEATYRTCIADAITQHQELEHMKVTVLRGIQEVIKQTDQTIRSATISYYQIMHMQTVALPVHYQTLCESSKQYDPGQQYGTHVKDLQMSEEPETHYEFEAYSAS-------------SVQQSVRPRTDS-ANAEAQSSAEVPQTAGETG----DTSSSQKDDQKRARGHMTHKSWGSTVSDTDSVGGGS---GLESPTTSTGDISK-MTRTSSTGTMSSNEDIDEKDA--NVTSFETPNINGIEPEI--VVPTGPFRNIGLSKAAQTHKLRKLRSPSKCRECDSYVYFQGAECEECFLACHKRCLETIAIQCGHKKLQGRLQLFGQDFLQVSSNSPDGIPFIIKKCIAEIERRALRMKGIYRVNGVKTRVEKLCQAFENGKELVELSQSSPHDISNVLKLYLRQLPEPIMPFRLYNSLMGLAKESLAVVGPEGADSGKGPDLMDLGPETDPELLVLVDRLKNLLKELPKPNTATLRYLARHLRRIAELEDDNKMSPSNLGIVFGPSLMRPRP---SGATVSLSSLVDYPYQARIVETLIVFYPSIFQS-------------ESSRPASSSTRTQSLQQQSSIDE------ERCSND---------------------------------------------------------------------------------------------------EQGLPDEPAAVELDKLEDHAE-----------------------------------------SCTGTPDSLEHSLDLDSDPEAEQPVDE----------------------------------------------------------------TSIQSRPAVLLVTLQSSSA--------------DPPALPESEPPELEDQSH----SLAALNINQSNNTTKTLTS------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1QL19-1", "uniprot_id": "A0A8M1QL19_DANRE", "id": "A0A8M1QL19-1", "name": "", "aln": "-----------------------MFSRKKKEQ--------ATKTPTASKKSNSAQNPS------LSILQEHSQNDTMD--------GSSMLTPPDSVALSCPGTP-CAHSRLSGCSSPVGTVRRPPGLSRHASAAGFPFQTS-GTWGFHKGYVR-APLNYGQAAEGLETSV-IEVEDIPSLLRDVARFAEAVEKLKDMVLGEVKEEPRSRPAVHECLGEVLRVLRQVISTYPLLNTVETLTAAGTLISKVKGFSYEGTTDAQK----KDFEKAIETIAVAFSSNVSELLMGEIDSTTLLSLPPTEKSRSMEDLYRLSSGQGPEGGGKYDQQDCISPQEVDILLQRSEGGVDSALSYSKSIAKYMKDIISYVDKRIALENEFSKGLQRLYQSCKQNIIQD-HMPLLSIFSLALEQDSEQSCGLQQTTNNIYTHSFLQPMTQRRQEHEKKRRDIKEQWQR----AKRKLADAESNLRKARQLYMSRCEEYERARTVANKVEEEQSGT---GSGSTTKALDRKRRLEEEARNKAEEAEATYRTCIADATTQQQELEDMKVNVLKQIQELIRQTDQILRACTISYYQTMHVQTAALPVHFQTLCESCKLFDPGQQYAAYVKNLQLRTERPLQYQFEPYSAS-------------SHQQLLRTRNNSLSNDQRQNSCEAPTTPEEAGF-GEGTVVKQRRGQVRDH-HQAHKSWPSTLSDTDSVGPGS---GLGSPTNSTGDISK-PSRPVSAATLSSNEDLEERDG--AMTQFEQS-INGIEPEI--VAPTGPFRNVGLSKAAKTHRLRKLRTPSKCRECDSYVYFQGAECEECFLACHKKCLESLAIQCGHKKLQGRLQLFGRDFSQVLHGKEDAVPFIIKKCITEIERRALKMKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPIMPFRMYNELMGLAKESLNSDASESTDGVKSPELVDRGPETEAEVLTLVDKLREVLKRLPNANIATLKYIIQHLRRVSELEQENKMSASNLGIVFGPTLMRPKP---TGATVSLSSLVDYPHQARIVEALIVFQQSIFIC-------------TTKSPAQRQDSETGAHEEPIRAH------QECGET---------------------------------------------------------------------------------------------------AHGDSVGSSGSQERSLDSDSD-----------------------------------------VEDPAAGFRPHRPPLVSQ-ESETSTEE----------------------------------------------------------------DQLSPR-----ASLDLSGL--------------VPETIPEQSVPEPAENTS----GRSQQ--------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0L8V3-1", "uniprot_id": "A0ABK0L8V3_RAT", "id": "A0ABK0L8V3-1", "name": "", "aln": "MRSGFWNVPDCVEDPGTFLVQPEAHPRASQSSNRHNLSNPLPSQPTMSGRRGPLKELLGWVCGWTRAWRTRLGTTGCGLSGLCPGEPPSVSEELPRKDCTETPSLEPPAMSLSTVAKGTGTLKRPTSLSRHASAAGFPLSGT-ATRTLGRGYRS-PLSAASPAELPTEGPFPDGVEDISTLLADVARFAEGLEKLKEFVLRDDLLEA-RRPLAHECLGEALRVMRQVISKYPLLNTVETLTAAGTLIAKVKAFHYECNNESDK----REFEKALETIAVSFSCTVSEFLLGEVDSSTLLAVPPGDPSQLVENLYG-SGSEGPPHSVEDCEEGCLPPEEVDMLLQRCEGGVDAALQYAKDMARYMKDLIGYLEKRTTLEMEFAKGLQKVVHNCRQNVTHAPHMPLLSIYSLALEQDLEFGHGMVQAVGTLQTQTFMQPLTLRRLEHERRRKEIKESWHR----AQRKLQEAEANLRKAKQGYKQRCEDHDKARLQVAKAEEEQQGTGPGAGTAASKALDKRRRLEEEAKNKAEEAMATYRTCVADAKTQKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQLMHMQTAPLPVNFQMLCESSKLYDPGQQYASHVRQLQRGEEPDVRYDFEPYVSTN------------AWSPIMRTRKGSFNPGDASGPEAAGSPPEEGG----TSEGAPNKDHRGGRGHQVHKSWPISISDTEVS-----------LDVSSGDLKK-FDRTSSSGTMSSNEELVDQEAGLVASAFDSADLNGMDPELPVAMPSGPFRHVGLSKAARTHRLRKLRTPAKCRECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSQAAHSTPDGVPFIIKKCVCEIERRALHTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPLISFRFYHELVGLAKDSLKAEAEAKAASRGR----QDGSESEAATLAMVGRLRELMRDLPAENRATLLYLLRHLRRIVEMEQDNKMTPGNLGIVFGPTLLRPRP---TDATVSLSSLVDYPHQARVIETLIVHYGLVFEE-------------EPEEAAGSQEGASAQCAQLETAEGIVFPQQEEADD---------------------------------------------------------------------------------------------------GNRESQVASNDSDSELEEASD-----------------------------------------LLSSSDASALHRLSFLEQTEAGLEEGP----------------------------------------------------------------QSHSGSE----EQLESEDA--------------APGHQLCSFNTNQSNNTT----QASLPTMRLRDGQITGGSGRKRQPQFV----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TBD2-1", "uniprot_id": "HMHA1_MOUSE", "id": "Q3TBD2-1", "name": "Rho GTPase-activating protein 45", "aln": "-----------------------MFSRKKRE---------LMKTPSISKK-------------------NRAGSP----------NPQSSSGELPRKDWTEAPGLEPPATSLSTVAKGTGTLKRPTSLSRHASAAGFPLSGT-ATWTLVRGYRS-PLSAASPAELPTEGAFPDGVEDISTLLADVARFAEGLEKLKECVLQDDLLEA-RRPLAHECLGEALRVMRQVISRYPLLNTVETLTAAGTLIAKVKAFHYECNNESDK----REFEKALETIAVSFSCTVSEFLLGEVDSSTLLAVPPGDPSQSMENLYG-AGTEGPPHNVEECEEGCLPPEEVDMLLQRCEGGVDAALQYAKDMARYMKDLISYLEKRTTLEMEFAKGLQKVVHNCRQSVTHEPHMPLLSIYSLALEQDLEFGHGMVQAAGTLQTQTFMQPLTLRRLEHERRRKEIKESWHR----AQRKLQEAEANLRKAKQGYKQRCEDHDKARLQVAKAEEEQQGTGPGAGTAASKALDKRRRLEEEAKNKAEEAMATYRTCVADAKTQKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQLMHMQTAPLPVNFQMLCESSKLYDPGQQYASHVRQLQRGEEPDVRYDFEPYVSNN------------SWSPIMRTRKGSFNPGDASGPEAAGSPPEEGG----TSEAAPNKDHRGGRGHQVHKSWPISISDTEVG-----------LDTSSGDLKK-FDRTSSSGTMSSSEELGDQEAGLVASAFDSADLNGMDPELPVAMPSGPFRHVGLSKAARTHRLRKLRTPAKCRECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSQAALSTPDGVPFIVKKCVCEIERRALHTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPLISFRFYHELVGLAKDSLKAEAEAKAASRGR----QGGSESEAATLAMVGRLRELMQDLPAENRATLLYLLKHLRRIVEMEQDNKMTPGNLGIVFGPTLLRPRP---TDATVSLSSLVDYPHQARVIETLIVHYGLVFEE-------------EPEEAPGSQEGASTQCGQLESAEGIVFPLQEEAED---------------------------------------------------------------------------------------------------GSRESHAASNDSDSELEDASD-----------------------------------------PLSSSDASALHRLSFLEQTEAGLEEGP----------------------------------------------------------------QSHSGSE----EQLEGEDG--------------APGPWLCHFNTNQSNNTS----RAPLPTMRLRGGQITGGTSQERQPQFV----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8N7TE50-1", "uniprot_id": "A0A8N7TE50_DANRE", "id": "A0A8N7TE50-1", "name": "Rho GTPase-activating protein 29", "aln": "-----------------------MFAAGMLQQ------------------------------------------------------------------------------------SSGGLNKRSLGMARIPDSRFFPLSSGSGSWGLSRTVKSGSLSSISSGSDNMDNMMGADPDYIMQLVNDVRRFADVLLHLKEAFNTKDHQDC-LHQVVHERLGELLRVLKAVISKHHSLNSVEILSAAGTLIAKVKGVNYKEVNEDNKQTLFSEIYTSIDTLAFTFGNVVSDFLMGDVENGSASGLPQASRSRSFENLTLESGGCGPEKDDPPGPSPPARVEQMDGALLRSDSGVESALLYAKAWSKYTKELLAWVDKRLNMDIECAKSYAKMAESAKALASQQEHMPFRDIYISAFRNDIEYSQLIMQTTAALQANKFMQPLQARKSELDKLRKEVKEQWQR----EQKKMHEADSALRKARLLQAQRQEEYEKARSSTSRVEEEQ------ISGAGGKQLEKRRKLEEEALLKAEEAQDHYKLCVTDVGVKRVDLAKTKSEILTQIRELVFQCDLTLKAVTVNWFQMQQAQVASLPINFQSLCENSKLYEPGLCYTEFVKSLPSDRSRVESFSFDISSTHNTGLKRAVNSTPAALVHLSQVSGDFLSADEVESHVQARTAKMPDGRSHSTTDVQALRIQGPFRVWRTSSQGGGMCSDSESAGGSSESRSMDSPTASPGDFKRRLPRTPSTGTMSSADDLDEREP----PSPSDNGLSEMVTEA--ASSPGPFRNTQMSKAAQTHKLRKLRAPSKCRECDSLVVFHGAECEECSLACHKKCLETLAIQCGHKKLQGKLHLFAIDFAQAAKNSPDGIPFIIKKCTSEIENRALNIKGIYRVNGAKSRVEKLCQAFENGKDLVELSDLYPHDISNVLKLYLRQLPEPLILFRYYNDFIGLAKESQSIIVDEVEASRGCP--TSDTPQISVELNRVLFKIKDLLRQLPPAHYKTLQFLIQHLHRVSERADENKMTSSNLGIIFGPTLIKPRQ---ADAEVSLSSLVDYPYQALIVELLIRHYEMIFDTPLSPLPPSSPVAESSPLPVKSRFTPQEKGQQLSRHSKSLVDIKEQQQSKAKMYKRHSSVIPSMHLMDEVKEGKIRSDKDFAAVGDKSDMNKLLSSSVPEMRNSPGLTRRNHVTRVQLRPPRPKLVSRPISMPAERLLNLSKVDECNVKNSVEQEETHSRDPVIEEVSEEEKPKSRAGNHYRKSYIDTQTLRRTWDKQYKHHDITPKTCPVDSGSNDTNVHTSSLTSSSFSEHSKSPSTVLANRPYTIAVRPGRTLRREGNISEFCPVPTAFRPPRTLQPPPGTFYKPPGGKSKSLTEVELQSVRATANSTEEEEEDDDDDDEEEEFGVEVSVDEPEPELDQETSVDAHDTSPLPESPSSSPEELGQNETKPVYQRLRSRRMQDLEHREAHFV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5U2Z7-1", "uniprot_id": "RHG24_RAT", "id": "Q5U2Z7-1", "name": "Rho GTPase-activating protein 24", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEENCDSTENPHSQGRQN-ATKCGWLRKQ----------GGFVKTWHTRWFVLKGDQLHYFKDEDETKPLGTIFLPGNKVIEHPCNEESPGKFLFEVVPGG--ERDRMTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGG----------------GIFGQKLEDTVRYEKRYGNRLAPMLVEQ----------CVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDC----GEKPSFDSNTDVHTVASLLKLYLRELPEPVVPYAKYEDFL-------SCATLLSKEEEAGVKELTKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSAQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDRLFPKDTEPQSKPQEGPNSNNNDGHK------------------------KVTMGQLQNKENNNTKESPVRRCSWDKPE----SPQRSSMDNGSPTALSGSKTNSPRNSIHKLDVSRSPPLTVKKNPAFNKGSGIVTNGSFSSSNAEGVEKTQTTPNGSLQARRTSSLKSSGTKMGT----------------HSVQNGTVRMGILNTDTLGNSLNGRSMSWLPNGYVTLRDNKQKEPAG---ESGQHNRLSTYDNVHQQFSLMNLDDKHSVDSATWSTSSCEISLPE-NSNSCRSSTTTCPEQDFYGGNFEDPVLDGPPQDDLSHPGDYENKSDRRSVGGRSSRATSSSDNSETFVGNTSS----------------NHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMLNLHDELDQERKKFTMIEIKMRN--------AERAKEDAEKRNDMLQKEMEQFFSTFGD----------------LTVEPRRSERGNTIWIQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2JTT7-1", "uniprot_id": "A0A0G2JTT7_RAT", "id": "A0A0G2JTT7-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLSPKIRQARRARSKSLVMGEQSRSPGRPLAPHKLGPVLKAGWLRKQ----------KSIMKNWQQRWFVLRGDQLFYYKDKDEGKPQGFISLQGTQVTELLPDPDDPGKHLFEITPGGAAEREKVPANPEALLLMASSQRDMEDWVQAIRRVIWAPLGGGTSRSSHAHPVEPLSTGIFGQRLEDTVHHERKFGPRLAPLLVEQ----------CVDFIRERGLSEEGLFRMPGQANLVRDLQDSFDC----GEKPLFDSTTDVHTVASLLKLYLRELPEPVIPFARYEDFL-------SCAQLLTKDEGEGTVELAKQVSNLPQANYNLLRYICRFLDEVQAHSDVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHGQLFATPSFEEPASPRG-----------------------------------TVQGTVEWGSEEVTRDHQGEPGSSGLP-----THRTSSLDG--PAAAVLSRTSPPRLGSQAGPAATSPGKRMHTLPGWK--SSFRQQGSRSES-PKGVSSSLEVP-----------IISSG---------------------------------------GN--------WLINGLSSLRSHRRASSGDRLKDTGSAQRLSTYDNVPPSS---HLSSTASVASTAWSVASSSREASIGSCTACRASNSSACSSLHTEWALEPSPLPSSSEGHPSP--DLGHSLDEACVGSGSSEPNDPGSPSQAHVR--------------------RCRALQGQVAELRAELCHQRIEYQRSLKSIEEGNSDLRKQMCRLEEELDQEKKKYAMLEIKLRN--------SERAREDAERRNQLLQREMEEFFATLGS----------------LTAGTKGARAPE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6A5M6-1", "uniprot_id": "A0A8I6A5M6_RAT", "id": "A0A8I6A5M6-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVSLQPGSALQETCVESLGTIKARSRSVMTGEQMAAFHPPTTPNPLERPIKMGWLKKQ----------RSIVKNWQQRYFVLKARQLYYYKDEEDSKPQGCMYLPGSTVKEIATNPEEAGKFVFEVIPAS---SDQNRTGQDSYVLMASSQVEMEEWVKFLRRVAGTPSGA-----------------VFGQRLDETVAYEQKFGPHLVPILVEK----------CSEFILEHGVSEEGIFRLPGQDNLVKQLRDAFDA----GERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFL-------LCGQLTNADEAKAQQELEKQLSILPRDNYNLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDAPLSPPAQ---------------------------------------KNDAKKAPVPRSSVGWDATEDPP-----LSRTDSFNNTASSPDATSPTGPQPGDQHQEDSGKAP------------------KENPGDWKMQSRKRTQTLP--------------------------------------------------------------------NRKCFLTSAFQGTTSS---------KLEIFKNEFWSP-----SSEAKAGEGHRRTMSQDLRHLS---NDQRTST--------YDNVPNPPVSQGNPAGELSP--PASDSKRDAPVSTDSEMESGSKNSGEEDPD-----------------------SLQRTVQHLQKEIEAQKQMYEEQIKNLEKENYDVWAKVVRLNEELERERKKFAALEISLRN--------VERSREDVEKRNRVLEEEVKEFVKSMEK----------------SKTKTDA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12128-1", "uniprot_id": "BAG7_YEAST", "id": "Q12128-1", "name": "Rho-GTPase-activating protein BAG7", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFNMNLLSTPSSEEGSPQNRSSSMSSVEGKKDRDTFTNLQNEFDGKVFGVS-------------LEESLKVAQEEVIIQKSTNEIGSIPVVIAK----------SGKYLKENALDTTGIFRIAGSNKRVRELQAVFSKPPDYGRKFEGWCDFNVHDIATLLKRYLNSLSEPLVPLALYDIFRN----PILENPKINEHKEQIIKDYEDIYMLLPQQNRHLILYLAALLNLFARNEKKNLMSASNLAAIVQPSLLS-HPKDEMCPKEYEASRTVIEFLILHASDIIPNTEKAN-----------------------------------------------------KDTMPHAG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TVAKFNNITVPEMAIDSDEEDFVHPSIDDHMLPRS-----------------------------RALSDSNNFTIHHHHHHHHALFPSPIDFDNNGLSVPRSFKG------------------------RTLSAESLSPRLSKLLGNVGNSSNTGIKDPTERVP-RGEHKTKHKQRQSWLRRLTSPSRTQP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . . : . : . ::.: : .: :: .. .. : . . : . : . : : . : : : : . ", "identical_positions": 0, "similar_positions": 37, "identity": "0.0%" }, { "cls_id": "homologset.agr.SGD:S000005662", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99NA5-1", "uniprot_id": "IDH3A_RAT", "id": "Q99NA5-1", "name": "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "aln": "MAGSAWVSKVSRLLGAFHN-----------------TKQVTRGFAGGVQTVTLIPGDGIGPEISASVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPPEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAENCKDIKFNEMYLDTVCLNMVQDPSQFD--VLVMPNLYGDILSDLCAGLIGG-LGVTQSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAAKIEAACFATIKDG-KSLTKDLGGNSKCSDFTEEICRRVKDLD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D6R2-1", "uniprot_id": "IDH3A_MOUSE", "id": "Q9D6R2-1", "name": "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "aln": "MAGSAWVSKVSRLLGAFHN-----------------TKQVTRGFAGGVQTVTLIPGDGIGPEISASVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPPEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEEASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAENCKDIKFNEMYLDTVCLNMVQDPSQFD--VLVMPNLYGDILSDLCAGLIGG-LGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAAKIEAACFATIKDG-KSLTKDLGGNAKCSDFTEEICRRVKDLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50213-1", "uniprot_id": "IDH3A_HUMAN", "id": "P50213-1", "name": "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "aln": "MAGPAWISKVSRLLGAFHN-----------------PKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFD--VLVMPNLYGDILSDLCAGLIGG-LGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDG-KSLTKDLGGNAKCSDFTEEICRRVKDLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWH4-1", "uniprot_id": "IDH3A_DROME", "id": "Q9VWH4-1", "name": "Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "aln": "MA-ARFIQKILNQLGLIAARDAPAVTATPAVSQVNATPAASRSYSSGTKKVTLIPGDGIGPEISAAVQKIFTAANVPIEWEAVDVTPVRGPDGKFGIPQAAIDSVNTNKIGLKGPLMTPVGKGHRSLNLALRKEFNLYANVRPCRSLEGYKTLYDDVDVVTIRENTEGEYSGIEHEIVDGVVQSIKLITEEASKRVAEYAFQYAKNNNRKKVTVVHKANIMRMSDGLFLRCVRDMAQKFPEIQFEEKYLDTVCLNMVQNPGKYD--VLVMPNLYGDILSDMCAGLVGG-LGLTPSGNMGLNG-ALFESVHGTAPDIAGKDLANPTALLLSAVMMLRHMELNTYADKIERAAFETIKEG-KYLTGDLGGRAKCSEFTNEICAKL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28241-1", "uniprot_id": "IDH2_YEAST", "id": "P28241-1", "name": "Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial", "aln": "MLRNTFFRNTSRRFLATVKQPSIG------------RYTGKPNPSTGKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSPIFVN-GLTTIPDPAVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVLIRENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGHK-ISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :. : . : . . : * .*::* ********* :* *** **:.**:** :*:.: * ** * :*: .* :.***** **:. ** *:** *** *.*:*****. *:**:** * :*::* ************** : **********. **:*: .:**:**: * .* .***:.* *::****:. :::::. :: :: :*. *::* :*. : * * **********: :** .* **:* *.*:* : ::**:***:******:* *********:****.** * :* :*: * : ** .* : * **.* :. *.**: : :: ", "identical_positions": 168, "similar_positions": 96, "identity": "43.41%" }, { "cls_id": "homologset.agr.SGD:S000005666", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5ND04-1", "uniprot_id": "HSF5_MOUSE", "id": "Q5ND04-1", "name": "Heat shock factor protein 5", "aln": "-------------MEEALLSTPINPNNFPAKLWRLVNSPRYRSIRWDGRGE-GLLIDQP-------LFEAELLSPPGPGAGGAGGAGSSGGGGGSGVGAAGAEPELFKTTNFTSFIRQLNLYGFRKVVLGGPGAAGPGPGPGAGGPAGDGPLHHFHSPHFR-------------RDQPQLLVHLKRLTSANKAKLAAGLEVPCRPPNRFQRLLITSASA--------SASASTSPLQHQDPPPQPAGPRPEQHGPVAVGQFHRSFRRDNLSPYSYVSTSSHNHSAFPLKGLDRTPIPPRTWQNSLGMH----------------PGQVETSPTFSDKGVPFPVLQRFPTEVTYTLQPSATSVHVQQGPQTMVSSSQKYSNYTPSAQYSQAYYPTAVLQCCSPPTHMDALSSCVTPTASSYAHCNYFQNPPMQSSYPVEFLPSNWPCSATDENKKTEVNLEAVFQIVDELHSSPKLEMVKVEPVETQCPSSQANRGQHILPNANSSNPSSTSQASQLEPLTPVGSD--------------------ITSFVVGTEQAITCSLPQSPEYIYTIHTAQPLENSTMQESATIQQTHVKLKEQLNHNPSPSSVVFVQEGLPFSTPQVDSSIKCQTNPSENILPSEQMGFLISEMGPANKSTKDTGLS------------------------TPARYRERRSNSQ-GKSPDLHLLVDVACKQEHFPKEEELKE---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G7F5-1", "uniprot_id": "A0A8I6G7F5_RAT", "id": "A0A8I6G7F5-1", "name": "Heat shock factor protein 5", "aln": "-------------MEEALLSTPINPNNFPAKLWRLVNSPRYRSIRWDGRGE-GLLIDQP-------LFEAELLSPPGPGAGGAGGAGSSGGGGGSGVGAAGAEPELFKTTNFTSFIRQLNLYGFRKVVLGGPGAAGPGPGPGAGGPAGDGPLHHFHSPHFR-------------RDQPQLLVHLKRLTSANKAKLAAGLEVPCRPPNRFQRLLITSASA--------SASASTSPLQHQDPPPQPAGPRPEQHGPVAVGQFHRSFRRDNLSPYSYVSTSSHNHSTFPLKGLDRTPIPPRTWQNSLGMH----------------PGQVETSPTFSDKGVPFPVLQRFPTEVTYTLQPSATSVHVQQGPQTMVSSSQKYSNYTPSAQYSQAYYPTAVLQCCSPSTHMDALSSCVTPTASSYAHCNYFQNPPMQSSYPVEFLPSNWPCSATDDSKKTEVNLEAVFQIVDELHSSPKLEMVKVEPVENQCPSSQSNRGQHILPNSNSSNPSSTSQASQLEPLTPVGSD--------------------ITSFVVGTEQAITCSLPQSPEYIYTIHTAQPLENSTMQESATMQQTHVKLKEQLSHNSPPSSVVLVQEGLPFSTPQVDSSIKCQTNPPESILPSEQMGFLISEMGPASKSSKDTGLS------------------------TPARYRERRSNSQ-GKSPDLHLLVDVACKQEHFPKEEELKE---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4G112-1", "uniprot_id": "HSF5_HUMAN", "id": "Q4G112-1", "name": "Heat shock factor protein 5", "aln": "--------------MEALLSTPINPNNFPAKLWRLVNSPRYRSIRWDGRGE-GLLIDQP-------LFEAELLSPPGP-------------GGGGGTAGAGAEPELFKTTSFTSFIRQLNLYGFRKVVLGGP---------GGGKPAGNGPLHHFHNPHFR-------------RDQPQLLVHLKRLTSANKAKLAAGLEVPCRPPNRFQRLLIT------------SASAATAPLQHQQPPP-PAGPRPEPHGPVAVGQFHRSFRRDSLSPYSCVSTPSHDHSTYPLKGLDRTPVPHRIWQNSLGMH----------------PGQVETSPTFSDKGVPFPVLQRFPTEVTYTLQPSTTSVHVQQGPQTMVSSSQKYSNYTPSAQYSQAYYPTAVLQCCSP-THMDALSSCVTPTASSYAHCNYFQNPSMQSSYPVEFLPSNWPCSTTDENTKTEVNLEAVFQIVDELHSSPKLEMVKVEPVENQCPTSPSYRGQHILANSNNSNPCSASQASQLEPLTPVGSD--------------------IMSFVVGTEQAVACSLPQSPEYIYTIHTAQPVENSTIQESAAIQQAHVKLKEHLNHNPSPSSVVFVQEGPPFSTHQVDANIKCQTSSRENILPSEQMGFLISEMGPASKPSEDTGLA------------------------TPARYREHRSNSQQGKSPDLHLLVDVACKQERFPKEEELKE---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TUW3-1", "uniprot_id": "A0AB32TUW3_DANRE", "id": "A0AB32TUW3-1", "name": "", "aln": "---------MAMDCDYSLLNVNINYHNFPAKLWRLTNNPQNSSVFWSPTGE-SLIVDQQ-------QFEVDLLT------------------------PIKLDNKPFKTSNFTSFIRQLNLYGFKKIFDGSP-------------RDKHRNRHHFYNPNFR-------------RGQPELLVHLKRLTLSKKTKTKIGEKESCRPLSRGQ------------------QKTQRNPAEENRGSAQLSGGAAHQQ---------PEYEQSPMTGHSWIFPCADASSFYSNTGLPLSVYP------------------------------YSSMPVGPHSGPAFLFPQDIPHHLSYPAG-----------------------------------LYSPVCQCCTHTQADQAGGNQTS--HLSYSHYAYYPQNYSVSHQQSSFQPTNWPVHHVSE-QRGDMNLDRAFRMVDDFQGLSNVRIVQVGPPVKPQLISNPP--------------------------------------------------------------------------LYTIPSAPKAQSVSLQS---------------------------IETMTFSPPKDTDTYEDHSQIKADLESLEQL--------------KDGGLS------------------------FKVTIEN-------VKEENIRNELQINTHRSSFWTDSDF-----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5XIQ7-1", "uniprot_id": "Q5XIQ7_RAT", "id": "Q5XIQ7-1", "name": "", "aln": "-----MAEAPSDMLDVSPNSLSTDSETSSGDPWCDNNTGQKDSELWAIIEESAFQVLAQ-------RFLIKRPP------------------HTLCASEPDEDSNLFSMTFPRKLWKIVGSDKFKSIWWDED-----------------GTYIVINEELFK-------------KEVLERKAPFRIFETDSMKSLVRQLNLYGFRKMRQN-----------------FQRSASLPDFLAEEKGISASCK-------------LQFYQNPNFLRDCPHLIERMKRRIGIKTVSRGAAP--------------------------------SLPDFKNK----HFRPDLGKMDDHSLG----------------------------------------------VAVQTSERNLLSGSSISNVYLRQKPSLTQGSSDSMDVIRSDFSLATSSSFRPPEEVLTHRPAPLNDVSSLHMDSQR-----------------------------------------------------------------------------------------IYTQANDSTVN--------------------------------------FIITSITQNRRDMSHLWNSCIEMQGE------------PSFQPGFP------------------------HFSSSSSTYSDSKAKGEPELPIHKERVASTTLASTSNHHPSS--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20134-1", "uniprot_id": "SFL1_YEAST", "id": "P20134-1", "name": "Flocculation suppression protein", "aln": "MSEEETVSAPAPASTPAPAGTDVGSGGAAAGIANAGAEGGDGAEDVKKHGSKMLVGPRPPQNAIFIHKLYQILEDESLHDLIWWTPSGLSFMIKPVERFSKALATYFKHTNITSFVRQLNIYGFHKVSHDHSSNDANSGDDANTNDDSNTHDDNSGNKNSSGDENTGGGVQEKEKSNPTKIWEFKHSSGIFKKGDIEGLKHIKRRASSRNNSSINSRKNSSNQNYDIDSGARVRPSSIQDPSTSSNSFGNFVPQIPGANNSIPEYFNNSHVTYENANHAPLESNNPEMQEQNRPPNFQDETLKHLKEINFDMVKIIESMQHFISLQHSFCSQSFTFKNVSKKKSENIVKDHQKQLQAFESDMLTFKQHVMSRAHRTIDSLCAVNAAATAASVAPAPAPTSTSAYAPKSQYEMMVPPGNQYVPQKSSSTTNIPSRFNTASVPPSQLFVQYQPQSQQHVTYAKQPAHVPNFINQPIPIQQLPPQYADTFSTPQMMHNPFASKNNNKPGNTKRTNSVLMDPLTPAASVGVQGPLNYPIMNINPSVRDYNKPVPQNMAPSPIYPINEPTTRLYSQPKMRSLGSTSSLPNDRRNSPLKLTPRSSLNEDSLYPKPRNSLKSSISGTSLSSSFTLVANNPAPIRYSQQGLLRSLNKAANCAPDSVTPLDSSVLTGPPPKNMDNLPAVSSNLINSPMNVEHSSSLSQAEPAPQIELPQPSLPTTSTTKNTGEADNSKRKGSGVYSLLNQEDSSTSSADPKTEDKAAPALKKVKM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . .. : . : . *. : .: : :. *:.: . . : :: : : : * . .: .. . . : : . . * .. . . : :. . :*: . : . . : : : :: . . ", "identical_positions": 5, "similar_positions": 59, "identity": "0.65%" }, { "cls_id": "homologset.agr.SGD:S000005667", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LPE7-1", "uniprot_id": "A0ABK0LPE7_RAT", "id": "A0ABK0LPE7-1", "name": "Actin-related protein 8", "aln": "----------------------------------------------------------------------------------------------------------------------------MLPSCSSSPRAFSPFLRFEVPGLHHHQKQKKEKSNFNRVVPSVPESSTGDAGGGHLDCGQPGDAAPARWFSTAYCGVGVPEPRGCWWSVVAEMTQAEKGDAENGKEKGGEKEKEQ-RGVKRPIVPALVPESLQEQIQSN---FIVVVHPGSTTLRIGRATDTLPASIPHVIARRHKQQGQPLYKDNWLLR--EGLNKPESNEQRQNGLKMVDQAIWSKKMSNGTRRIPVSPEQ------TRSYNKQMRPAILDHCSGNKWTNTSHQPEYLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQ-KYLEIPLKDLKYYRCILLIPDIYNKQHVKELVHMILMKMGFAGIVVHQESVCATFGSGLS-STCVVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLAN-KMDCLLLQHLKETFCHLDQDISGLQDHEFQIRHPDSPALLYQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHRSQGDPED----PHDEHYLLATQSKQEQSAKATADRKSASKPIGFEGDLRGQSSDLPER--LHSQEVDLASSQGDCLMAGNESEEALTALMSRKTAISL------FEGKALGLDKAILHSVDCCSS--------DDTKKKMYSSILVVG----------GGLMFHKAQEFLQHRILNKMPPSFRRIIEN--------VDVITRPK--------------VSCFAI---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2S9-1", "uniprot_id": "ARP8_MOUSE", "id": "Q8R2S9-1", "name": "Actin-related protein 8", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQAEKGDAENGKEKGGEKEKEQ-RGVKRPIVPALVPESLQEQIQSN---FIVVIHPGSTTLRLGRATDTLPVSVPHVIARRHKQQGQPLYKDNWLLR--EGLNKPESNEQRQNGLKMVDQAIWSKKMSNGTRRIPVSPEQ------TRSYNKQMRPAILDHCSGNKWTNTSQQPEYLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQ-KYLEIPLKDLKYYRCILLIPDIYNKQHVKELVHMILMKMGFAGIVVHQESVCATFGSGLS-STCVVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTN-KMDCLLLQHLKETFCHLDQDISGLQDHEFQIRHPDSPALLYQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHRSQGDPED----PHDEHYLLATQSKQEQSAKATADRKSASKPIGFEGDLRGQSSDLPER--LHSQEVDLASSQGDCLMAGNESEEALTALMSRKTAISL------FEGKALGLDKAILHSVDCCSS--------DDTKKKMYSSILVVG----------GGLMFHKAQEFLQHRILNKMPPSFRRIIEN--------VDVITRPKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H981-1", "uniprot_id": "ARP8_HUMAN", "id": "Q9H981-1", "name": "Actin-related protein 8", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQAEKGDTENGKEKGGEKEKEQ-RGVKRPIVPALVPESLQEQIQSN---FIIVIHPGSTTLRIGRATDTLPASIPHVIARRHKQQGQPLYKDSWLLR--EGLNKPESNEQRQNGLKMVDQAIWSKKMSNGTRRIPVSPEQ------ARSYNKQMRPAILDHCSGNKWTNTSHHPEYLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQ-KYLEIPLKDLKYYRCILLIPDIYNKQHVKELVNMILMKMGFSGIVVHQESVCATYGSGLS-STCIVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTN-KMDCLLLQHLKETFCHLDQDISGLQDHEFQIRHPDSPALLYQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHRSQGDPED----PHDEHYLLATQSKQEQSAKATADRKSASKPIGFEGDLRGQSSDLPER--LHSQEVDLGSAQGDGLMAGNDSEEALTALMSRKTAISL------FEGKALGLDKAILHSIDCCSS--------DDTKKKMYSSILVVG----------GGLMFHKAQEFLQHRILNKMPPSFRRIIEN--------VDVITRPKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P59679-1", "uniprot_id": "ARP8_DANRE", "id": "P59679-1", "name": "Actin-related protein 8", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQTDR-DAENGRDREKDREKEQQRGVKRPIMPAAVPEPVQEQIQAN---FIVVIHPGSRTLRLGRATDTLPISVPHVIARRHKHPGQSRYEDKCLLR--EGLNSADSNEQRQNGLKMVDQVIWSKKMSNGVRRTPVSAEQ------ARLYNRQIRPAVLDPNSKVSWTNTSHHPEYVVGEEALYVNPTDCYSVHWPVCRGRLNLHSGSGGSLSAVMMDLEHIWTHALQ-KLLQIPLKDLKYYRCILLIPDIYNRQHVKEIVNMLLVKMGFSAVVVHQESVCATFGSGLS-SACVVDVGDQKTSVCCVEDGVSHRSSRLCLAYGGSDVTRCFFWLMQRAGFPYRDCQLGN-KLDCVLLQQLKESFCHLDQDISGLQDHEFRTRFPDSPVLLYQLRLGDEKLQAPMTLFYPAAFGIVGQRMTSLLHRSQGDAED----PHDEHFLLTTQSKQDQSSKASADRKSFPKPSSFEGES--SVCEVSDRS-SLGQDLDLGHSQAECLVGGAETEETPSALLSRKTAMSQ------FEGKALGIDKAILHSIDSCAS--------DETKRKMYSCILVVG----------GGLLFHGAQEFLQHRILNKMPPSFRCMVES--------VDVITRPKDTDARVCVWKGGSVLACLDTTQELWIHQREWQRFGVRMLRERAAFVW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VX09-1", "uniprot_id": "ARP8_DROME", "id": "Q9VX09-1", "name": "Actin-related protein 8", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQRSRASSTSSGRHPAPP--------------PIGLPQPQAQPLEAP---KIIVIHPGSQHLRIGRAADLNPLTLLHAVAYRRRPGASDRPHHDPLLPPLDNVNSNSGLMVEFEEQRLVVSRILQHCVVDNKNRLRVATPPQQLAHFNRSSQAEKVPAPSGQMADEPWLDREAPVLFDDRILRLGAVDARNYDIHFPIQRGELNVHNEKGGSLQASMQHLERIWSYALE-ERLKIPLRKLGTHCAVLVVNDVYVRRHLREFVTLLLRRLGFRRCFLVQDSVASTFGAGIG-YGCVVDIGAQKTSIACIEDGISQLDARVRLSYGGGDLDQVLLLLLRKCGFPYRECNVQESYVDAHLLDELKEKFCHLNASVCGAQEKHFNLRKHNGQWLRYTIQVGDEALMAPLALFHTELLNITGRTKAVFTQQAVQDQYD----CEDCFDAEYLKETGRKNGVRGGDILQLSTSAGYQPRPQLPVTADDEE--LIVVDQDETISNCQSQLG----AQTAGGQMNSNGCYHN------GQGLVLPLDQAIIQSINRLSS--------YETKRKMFGSILLVG----------SSAKLPGLAAWLEQRISQQVQSEVNVLIKG--------MDAG---------MVAWKGAAIMSVLESARELWISQNDWQRHGLRVLRERSPFLW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12386-1", "uniprot_id": "ARP8_YEAST", "id": "Q12386-1", "name": "Actin-like protein ARP8", "aln": "MSQEEAESSIIYEEPIDIPLEDDDDEDELEEENSVPLSSQADQENAENESDDSVDNVVGSETPRSVTGLSVDPRDVADEEDEDEEGEDEDEDEDDNDVDNEDENDNDNANENENELGSSRDKRAPPAVQTSKRYKKYPKLDPAKAPPGKKVPLHLLEKRRLGRIKAAEEFAKTLKKIGIEKVETTTLPATGLFQPLMLINQKNYSSDYLKKDDQIFALRDRKFLRNNNTSQISSTNTPDVIDLKSLPHSEASAAPLNDEIDLNDPTATIVIHPGSNSIKIGFPKDDHPVVVPNCVAVPKKWLDLENSEH------VENVCLQREQSEEFNNIKSEMEKNFRERMRYYKRKVPGNAHEQ-----VVSFNENSKPEIISEKNDPSPIEWIFDDSKLYYGSDALRCVDEKFVIRKPFRGGSFNVKSPYYKSLAELISDVTKLLEHALNSETLNVKPTKFNQYKVVLVIPDIFKKSHVETFIRVLLTELQFQAVAIIQESLATCYGAGISTSTCVVNIGAAETRIACVDEGTVLEHSAITLDYGGDDITRLFALFLLQSDFPLQDWKIDS-KHGWLLAERLKKNFTTFQDADVAVQLYNFMNRSPNQPTEKYEFKLFDEVMLAPLALFFPQIFKLIRTSSHKNSSLEFQLPESRDLFTNELNDWNSLSQFESKEGNLYCDLNDDLKILNRILDAHNIIDQLQDKPENYGNTLKENFAPLEKAIVQSIANASITADVTRMNSFYSNILIVGGSSKIPALDFILTDRINIWRPSLLSSASFPQFYKKLTKEIKDLEGHYVNAPDKTEDENKQILQAQIKEKIVEELEEQHQNIEHQNGNEHIFPVSIIPPPRDMNPALIIWKGASVLAQIKLVEELFITNSDWDVHGSRILQYKCIFTY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ... . . . : :: :*:**** :::* . * * : : :* :: .. :.: . : : . . : .: . : : * . : : :: *. * :*:: ** : .: : :*:: : *:: .: : :*:: *:: : *:. :: ::* .: * : *:*:.: :*:*:. *:*::* :* :.*:::* : : * ***.*: : : :: :..** :: :: . . * :.**:.* :: . * .* * : * ::: ** : **::**.. : : . .: .. :.. * . . . :. . : : : : . :. . .. :* : . :: . : :*: * : . ::.:* ::: . . : . :. :: : ", "identical_positions": 58, "similar_positions": 178, "identity": "6.49%" }, { "cls_id": "homologset.agr.SGD:S000005668", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P13086-1", "uniprot_id": "SUCA_RAT", "id": "P13086-1", "name": "Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial", "aln": "MTAAVVAAAATATMVSGSSGLAAARLLSRTFLLQQNGIRHGSYTASRKNIYIDKNTKVICQGFTGKQGTFHSQQALEYGTKLVGGTTPGKGGKKHLGLPVFNTVKEAKEKTGATASVIYVPPPFAAAAINEAIDAEIPLVVCITEGIPQQDMVRVKHKLTRQGKTRLIGPNCPGIINPG-ECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSLCIGIGGDPFNGTNFIDCLDVFLKDPATEGIVLIGEIGGHAEENAAEFLKEHN-SGPKAKPVVSFIAGITAPPGR--RMGHAGAIIAGGKGGAKEKISALQSAGVIVSMSPAQLGTCMYKEFEKRKML-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUM5-1", "uniprot_id": "SUCA_MOUSE", "id": "Q9WUM5-1", "name": "Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial", "aln": "MTATVVAAAATATMVSSSSGLAAARLLSRTFLLQQNGIRHGSYTASRKHIYIDKNTKIICQGFTGKQGTFHSQQALEYGTKLVGGTTPGKGGQKHLGLPVFNTVKEAKEKTGATASVIYVPPPFAAAAINEAIDAEIPLVVCITEGIPQQDMVRVKHRLTRQGTTRLIGPNCPGVINPG-ECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSLCIGIGGDPFNGTDFIDCLEVFLNDPATEGIILIGEIGGHAEENAAAFLKEHN-SGPKAKPVVSFIAGITAPPGR--RMGHAGAIIAGGKGGAKEKISALQSAGVVVSMSPAQLGTTIYKEFEKRKML-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53597-1", "uniprot_id": "SUCA_HUMAN", "id": "P53597-1", "name": "Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial", "aln": "MTATLAAAADIATMVSGSSGLAAARLLSRSFLLPQNGIRHCSYTASRQHLYVDKNTKIICQGFTGKQGTFHSQQALEYGTKLVGGTTPGKGGQTHLGLPVFNTVKEAKEQTGATASVIYVPPPFAAAAINEAIEAEIPLVVCITEGIPQQDMVRVKHKLLRQEKTRLIGPNCPGVINPG-ECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSLCVGIGGDPFNGTDFIDCLEIFLNDSATEGIILIGEIGGNAEENAAEFLKQHN-SGPNSKPVVSFIAGLTAPPGR--RMGHAGAIIAGGKGGAKEKISALQSAGVVVSMSPAQLGTTIYKEFEKRKML-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q94522-1", "uniprot_id": "SUCA_DROME", "id": "Q94522-1", "name": "Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial", "aln": "MAASM-----------------RALLKVRDGFVAGVR-CNSQYNKTRGNLKLNGDSRVICQGFTGKQGTFHSQQALEYGTKLVGGISPKKGGTQHLGLPVFASVAEAKKATDPHATVIYVPPPGAAAAIIEALEAEIPLIVCITEGVPQHDMVKVKHALISQSKSRLVGPNCPGIIAPE-QCKIGIMPGHIHKRGKIGVVSRSGTLTYEAVHQTTEVGLGQTLCVGIGGDPFNGTDFIDCLEVFLKDPETKGIILIGEIGGVAEEKAADYLTEYN-SGIKAKPVVSFIAGVSAPPGR--RMGHAGAIISGGKGGANDKIAALEKAGVIVTRSPAKMGHELFKEMKRLELV-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDW7-1", "uniprot_id": "Q9VDW7_DROME", "id": "Q9VDW7-1", "name": "Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial", "aln": "MSLNR-----------------GSKMLLRALTPQILRRGKADYGKTVCNLKINKATKVLVQGFTGKQATFHSEESIKYGTNIVGGVNPKKGGTEHLGKPVFKSVAEAVEKAKPDATVIFIPPPSAAEGICAAIESEIGLIVAITEGIPQADMVRISQMLNCQEKSRLLGPNCPGIISPD-QCKIGIMPGDIHKRGVVGIVSRSGTLTYESVHQTTNVGLGQALCVGLGGDPFNGTSFIDALKVFLSDKEIKGIVMIGEIGGSAEEEAADFLKEKN-TGCEAKPVVGFIAGQTAPPGR--RMGHAGAIISGGKGAAKDKVAALEKAGVRMTANPCHLGSTLLEEMIRLKLVPKPNKKKAQAGKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53598-1", "uniprot_id": "SUCA_YEAST", "id": "P53598-1", "name": "Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial", "aln": "MLRSTVS--------------KASLKICRHFHRESIP-----YDKTIKNLLLPKDTKVIFQGFTGKQGTFHASISQEYGTNVVGGTNPKKAGQTHLGQPVFASVKDAIKETGATASAIFVPPPIAAAAIKESIEAEIPLAVCITEGIPQHDMLYIAEMLQTQDKTRLVGPNCPGIINPATKVRIGIQPPKIFQAGKIGIISRSGTLTYEAVQQTTKTDLGQSLVIGMGGDAFPGTDFIDALKLFLEDETTEGIIMLGEIGGKAEIEAAQFLKEYNFSRSKPMPVASFIAGTVAGQMKGVRMGHSGAIVEGSGTDAESKKQALRDVGVAVVESPGYLGQALLDQFAKFK---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : * * : :: : :::: *******.***:. : :***::*** .* *.* *** *** :* :* : : . *:.*::*** ** .* ::::** * *.****:** **: : . * * .:**:******:* * : :*** * .*.: * :*::*********:*:***:..***:* :*:***.* **.***.*.:**.* :**:::***** ** :** :*.: * : :. **..**** * : ****:***: *. *:.* **...** : .* :* : .:: : : ", "identical_positions": 136, "similar_positions": 94, "identity": "37.47%" }, { "cls_id": "homologset.agr.SGD:S000005669", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DEJ6-1", "uniprot_id": "B5DEJ6_RAT", "id": "B5DEJ6-1", "name": "Thiamine pyrophosphokinase", "aln": "--------------------MEHVFTPLEPLLPTGDLKFCLVVLNQTLDP---HFRHLWRKALLRACADGGANHLYDLTEGE---RESFLPEFINGDFDSIRPEVKEYYTKKGCDLISTPDQDHTDFTKCLQVLQRKIEE--------------------------------------KELQVDVIVTLGGLGGRFDQIMASVNTLFQATD-IIPVPIIIIQKESLIYLLQPG-KHRLRVDTGMEG---SWCGLIPVGQPCNHVTTTGLKWNLTNDVLGFGT-LVSTSNTYDGSG------LVTVETDHPLLWTMAIKT--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0M5-1", "uniprot_id": "TPK1_MOUSE", "id": "Q9R0M5-1", "name": "Thiamine pyrophosphokinase 1", "aln": "--------------------MEHAFTPLEPLLPTGNLKYCLVVLNQPLDA---RFRHLWKKALLRACADGGANHLYDLTEGE---RESFLPEFVSGDFDSIRPEVKEYYTKKGCDLISTPDQDHTDFTKCLQVLQRKIEE--------------------------------------KELQVDVIVTLGGLGGRFDQIMASVNTLFQATH-ITPVPIIIIQKDSLIYLLQPG-KHRLHVDTGMEG---SWCGLIPVGQPCNQVTTTGLKWNLTNDVLGFGT-LVSTSNTYDGSG------LVTVETDHPLLWTMAIKS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H3S4-1", "uniprot_id": "TPK1_HUMAN", "id": "Q9H3S4-1", "name": "Thiamine pyrophosphokinase 1", "aln": "--------------------MEHAFTPLEPLLSTGNLKYCLVILNQPLDN---YFRHLWNKALLRACADGGANRLYDITEGE---RESFLPEFINGDFDSIRPEVREYYATKGCELISTPDQDHTDFTKCLKMLQKKIEE--------------------------------------KDLKVDVIVTLGGLAGRFDQIMASVNTLFQATH-ITPFPIIIIQEESLIYLLQPG-KHRLHVDTGMEG---DWCGLIPVGQPCMQVTTTGLKWNLTNDVLAFGT-LVSTSNTYDGSG------VVTVETDHPLLWTMAIKS--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RBJ9-1", "uniprot_id": "F1RBJ9_DANRE", "id": "F1RBJ9-1", "name": "Thiamine pyrophosphokinase", "aln": "---------------------MDEFTPLDCLLPSGKQRICLVILNQPLDER--YFHVLWSKAQIRACADGGANHLYRLTEGR---RESFLPDYINGDFDSILPEVKAFYAGKNCKLMETPDQDLTDFTKCLAIMLEEIKA--------------------------------------KKLQIDSIVTLGGLGGRFDQTMATVETLFHAQK-MTDLPVVVIQDSSLAFLLKEGRHHQLNVNTGMEG---KWCSLVPVGSPC-LTTTSGLKWNLDNQVLAFGQ-LVSTSNTYEDHDPKDCRKPVTITTDNPLLWSMGIKRLQSSQTFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35202-1", "uniprot_id": "THI80_YEAST", "id": "P35202-1", "name": "Thiamine pyrophosphokinase", "aln": "MSEECIENPERIKIGTDLINIRNKMNLKELIHPNEDENSTLLILNQKIDIPRPLFYKIWKLHDLKVCADGAANRLYDYLDDDETLRIKYLPNYIIGDLDSLSEKVYKYYRKNKVTIIKQTTQYSTDFTKCVNLISLHFNSPEFRSLISNKDNLQSNHGIELEKGIHTLYNTMTESLVFSKVTPISLLALGGIGGRFDQTVHSITQLYTLSENASYFKLCYMTPTDLIFLIKKN-GTLIEYDPQFRNTCIGNCGLLPIGEATLVKETRGLKWDVKNWPTSVVTGRVSSSNRFVGDN------CCFIDTKDDIILNVEIFVDKLIDFL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : : .. . . *::*** :* * :* ::.****.**:** :. * .:**::: **:**: :* :* : ::. . * ******: :: .:: ..: :::***:.***** : :: *: . . : : .* :*:: . :. :. :.. *.*:*:*.. * ****:: * .. **:** : . . : *.. :: .: * ", "identical_positions": 58, "similar_positions": 88, "identity": "17.74%" }, { "cls_id": "homologset.agr.SGD:S000005670", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4QY64-1", "uniprot_id": "ATAD5_MOUSE", "id": "Q4QY64-1", "name": "ATPase family AAA domain-containing protein 5", "aln": "MVGVLSMAAAAAPLPVKDYEIEPCKKRRKDDDNSSCETITKYLSPIGKTGDKVFSPPKPSNILHYFRKTSLTTEKPQSTKAYKIKPSPPLLVGNSKDCKTPLEVFSNREFKRKRKRVSLSSQLNDIKIQDECPVEISNNDSKEDGGLS-DCVESSASVSLYKEHVEVLAESIE-DSRNQPNTKSSKK---KVNPKQCTTKSDDRILRKRKRSKVTGQSESVPLADELSLPEDGGKDSKLTKPSLAEEN------DSRTHATKRADLKESTITVSYEEFVKSHKAAKVEEIPDPAVPACVPSG-PGEAVKSGSEGELSGSCEPSPQLHLKTVTVLAQVHPTPPKKKGKIPPIFLKQKQPELENSLSDPENEQPVQKRKSNVVIQEGQLELAVLEAWNSEASVPKCSMEERQQFMRAFRQPPPDTLKNGFKKPLEKQKDPSEKSVHEG--DSSSEKIIENPNIQRVSSQGCLQSHADRGSFPKEKSKKPNKKGKKTRTT---AGGNREENIQKEKTAFSLKDEQDQNSLRRSVRQ-KSEVLKSNALLNSENLVCEDTAHDSVQ--MSLCNRNK-SRSSSTPTRDM-VTHHRAEPGSSLEYVSTRQPIRRSLRSCSTPATNALGGTESEDAQDTIPVKASTPKSARTSEKHNLYTAELIIVSSDSESPIRMKFTRISTPKKSKKSS----KKSETTEEELTSQKKKANSTSKNISKAKELIEEAKAFQIGGSK-TEETVVPLRRSSRHQARSAKEKSPEIDDSVIVIDSSPTSIREPEKSQKKLQNLNDVLGKKLNKSSKNVPGKMKIAPLFLAKRTKRAAIPVFDLDESSQDSSEQTQDCDVQFKAKRDFLMSGLPDLLKRQIAKKAAALDVYNAVSTSFQRVVHVQQKDDEYWLWHLKPPSCPLLTEFKELNTKVTDLSEYVVAFGEFSTLNPNPRS-NPAAVMMRTRKDFTKEVRNLLLEEIKCSNPEFSLEKYFPLLLKKRIEHQVLCEGHGKQASPQLQPDVSQKETKRKQVATGNQKSKRKRQNEYSVSPEEMKGRSKDLDERISSSCTNLDPSRDSGTEDMLWTEKYQPQNSNELIGNELAVKKLHSWLKDWKRRAELEERHNLKGKRDEKEEGILDLSDSTDFKGSSDDEE-NRLCNTVLITGPTGVGKTAAVYACAQELG-----FKIFEVNASSQRSGRQILSQLKEATQSHQVDKQGVN----SQKPCFFNNYNIGKSPKKLN---SPGKVVTSPRKLPPSSPKTSGQKRALLPKTLANYFKVSSKSKSNDDVGALMGDDKGVKNSSLEQRQLIQTKSTNANNSHIKDVGAEESNRKKATSLILFEEVDVIFD-EDAGFLNAVKTFMATTKRPVILTTSDP-TFSLVFDGCFEEIN--FSIPSLLNVASYLQVICLVENFRTDFKD--FVTLLTANACDIRKSILYLQFWIRSGGGILEERP---LSHCRENSRNT-LVCSEDGSDANINSKKPKRNRVALPRCDTGCAEALFGLKNIASPSQDLLSLLKHKITTKEEWQKLIQVLTEFHVQNIDLLHSNLEVILPLPVHVVPDVRGAYGFPVTTQASAP-ASMGHLTRKQSK-DQPLRKSQKRKQKK-MVILDDSDLFDTGLDFSGELPSLSPAPSLSVEDNIRRD--SNPEIKTQNSGFKP---HSVPQPPKTLAEKKCCMLVSHCLNSLSEFMENMSFIDALLTDP--GEQNELGRSAFHWTNGRVKSGLCDEFSLENRDRWAPQSAGELKATAEALSFTECSSTIS-KALESLNSCKQLERDPTNELTVCVSQRRHDACFRQSAANLDN---ADKRMAVIKSVFSSRSFLTLGNKQASIIDYLPTLRNICRTEKLKEQEKNKRRFLHYFEGIHLEIPEETITTLAADFP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A058-1", "uniprot_id": "D4A058_RAT", "id": "D4A058-1", "name": "ATPase family AAA domain-containing protein 5", "aln": "MVGVLTMAAAAAPPPVKDCEIEPCRKRRKDDDSSSCETITKYLSPIGKTEDKVFSPSKPNNILHYFRKTSPTTEKLQSTKECKLKPSPPLLVGNSKDCKIPLEVFSNRESKKKRKRVSLSHQLNDVKIENESPVEISNDDSKEDCGLS-DFVENSTSVFLYKKHVEALAESIQEDSRNQSNTMTSKKNSKKVNPKQGTTKNDGKTLRKRKHSQGTDQSESVLVADEISLPGEGGKDSRLTKASLTDENRTAHHVDSRAHATKIADLNESTITVSYEEFLKSHKTAKVEDIPDLAGPACVPSG-PSEAIKSGSEGEPE-SCEPSPHLHLKTVTVLAQVHPTPPKKKRKIPPIFLKQKQLELENSFSDPENEQTVQKRKSNVVVQEGQLELAVLEAWSSEASVPKCSMEERQQFMRAFRQPPSETLRNGLKKPLEKQKDPSEKSVNEG--DSNSEKIIENPNIQRVSNQDCSQAHADRGGFPKEKSKRPNKKGKKTRTT---AAGNREENMQKEKTAFSLKDNQDQNTLRRSVRQ-KSEVFKSSALLNSENLVSEDTARDSVK--PSLCDRNK-SRRGSTPTRDM-VTHGKAEPGSGLVNVSTPKPTRRSLRGSSTPTTVTLGGTESEDAQDTDPVKASTPKAARISEKPSLYTAELIIISSDSESPIRMKFTRISTPKKSKKSS----KKSERTKEELTSQKNKANNTSKKISKAKQLIERAKAFQVSGSK-AEETVVPLRRSSRHQTRLEREKSPETDDSVILIDSNPTSIRQPEKNQKKLQNLNDVLGKKLNKSSKKVPGKMKIAPLFLTKKTKRTAISAFDLDESSQDSSGQTQDCDVQFKAKRDFLMSGLPDLLKRQIAKRAAALDVYNAVSTSFQRVVHVQQKDDEYWLWHLKPPSCPLLTEFKELNTKVTDLSKCLVAFGEFSTLNPNPRS-NPAVVLMRTRKEFTKEVRNLLLEEIKWSNPEFSLGKYFPLLLKKRIEHQVLCEGHGKQASPQLQPDVSQKETKRKQVETGSQKSKRKKPNEYSVSPEKIKGKSKELDKRISSSCINLDPSKESGTEDMLWTEKYQPQNSNELVGNELAIKKLHSWLKDWKRRAELEERQNLKGKRDEKEE---DLSDGTDFKGSSDDEE-YRLCNTVLITGPTGVGKTAAVYACAQELG-----FKIFEVNASSQRSGRQILSQLREATQSHQVDKQGAN----SQKPCFFSNYNIGKSPKKLN---SPGKVITSPRKLPPLSPKTGGQKRALLPKTLANYFKVSSKSNNNEDVGARPGNDKGVKNSSLEQRQIIQTKSTNANNSNIKDFGAEESNRKNATSLILFEEVDVIFD-EDAGFLNAVKTFMATTKRPVILTTSDP-TFSLVFDGCFEEIN--FNIPSLLNVASYLQVICLVENFRTDFKD--FVTLLTANACDIRKSILYLQFWIRSGGGILEERP---LSHCRENSRNT-LVCSEHESDANINSKNTKRNRVALPRCDTGCAEALFGLKNIACPSQDLLSSLKHKITTKEEWQRLIQLLTEFHMQNVDLLHSNLEFILPLPVNMIPEVRGAYGFPVTTQASAP-ASMKLLNRKQSE-DQPLRKSQKRKQKK-MVTLDDSDLFDTSLDFSGELPSLSPAASSSEEDNTSRDRGSNPEIKTQNKGFKP---HSLPQPPKTLAEKKCCVLVSHCLNSLSEFMENMSFVDALFTDP--GEQNELGKSAFHWTNGKVKSGLCDEFSLENRDGWSPRSSEELKATAEALSFTKCSSTIS-KALESLNSCKQLGRDPTTELTFCVSQRSHDVCFRQSAANLYN---ADKRMAVIKSVFSTPSFLTLGNKQASIIDYLPTLRNICRTEKLKEQEKNKRRFLHYFEGIHLDIPEETITPLAADFP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96QE3-1", "uniprot_id": "ATAD5_HUMAN", "id": "Q96QE3-1", "name": "ATPase family AAA domain-containing protein 5", "aln": "MVGVLAMAAAAAPPPVKDCEIEPCKKRKKDDDTSTCKTITKYLSPLGKTRDRVFAPPKPSNILDYFRKTSPTNEKTQLGKECKIKSPESVPVDSNKDCTTPLEMFSNVEFKKKRKRVNLSHQLNNIKTENEAPIEISSDDSKEDYSLNNDFVESSTSVLRYKKQVEVLAENIQ-DTKSQPNTMTSLQNSKKVNPKQGTTKNDFKKLRKRKCRDVVDLSESLPLAEELNLLKKDGKDTKQMENTTSHAN-------SRDNVTEAAQLNDSIITVSYEEFLKSHKENKVEEIPDSTMSICVPSETVDEIVKSGYISESE-NSEISQQVRFKTVTVLAQVHPIPPKKTGKIPRIFLKQKQFEMENSLSDPENEQTVQKRKSNVVIQEEELELAVLEAGSSEAVKPKCTLEERQQFMKAFRQPASDALKNGVKKSSDKQKDLNEKCLYEVGRDDNSKKIMENSGIQMVSKNGNLQLHTDKGSFLKEKNKKLKKKNKKTLDTGAIPGKNREGNTQKKETTFFLKEKQYQN--RMSLRQRKTEFFKSSTLFNNESLVYEDIANDDLLKVSSLCNNNKLSRKTSIPVKDIKLTQSKAESEASLLNVSTPKSTRRSGRISSTPTTETIRGIDSDDVQDNSQLKASTQKAANLSEKHSLYTAELITVPFDSESPIRMKFTRISTPKKSKKKSNKRSEKSEATDGGFTSQIRKASNTSKNISKAKQLIEKAKALHISRSKVTEEIAIPLRRSSRHQTLPERKKLSETEDSVIIIDSSPTALKHPEKNQKKLQCLNDVLGKKLNTSTKNVPGKMKVAPLFLVRKAQKAADPVPSFDESSQDTSEKSQDCDVQCKAKRDFLMSGLPDLLKRQIAKKAAALDVYNAVSTSFQRVVHVQQKDDGCCLWHLKPPSCPLLTKFKELNTKVIDLSKCGIALGEFSTLNSKLKSGNSAAVFMRTRKEFTEEVRNLLLEEIRWSNPEFSLKKYFPLLLKKQIEHQVLSS--ECHSKQELEADVSHKETKRKLVEAENSKSKRKKPNEYSKNLEKTNRKSEELSKRNNSSGIKLDSSKDSGTEDMLWTEKYQPQTASELIGNELAIKKLHSWLKDWKRRAELEERQNLKGKRDEKHE---DFSGGIDFKGSSDDEEESRLCNTVLITGPTGVGKTAAVYACAQELG-----FKIFEVNASSQRSGRQILSQLKEATQSHQVDKQGVN----SQKPCFFNSYYIGKSPKKIS---SPKKVVTSPRKVPPPSPKSSGPKRALPPKTLANYFKVSPKPKNNEEIGMLLENNKGIKN-SFEQKQITQTKSTNATNSNVKDVGAEEPSRKNATSLILFEEVDVIFD-EDAGFLNAIKTFMATTKRPVILTTSDP-TFSLMFDGCFEEIK--FSTPSLLNVASYLQMICLTENFRTDVKD--FVTLLTANTCDIRKSILYLQFWIRSGGGVLEERP---LTLYRGNSRNVQLVCSEHGLDNKIYPKNTKKKRVDLPKCDSGCAETLFGLKNIFSPSEDLFSFLKHKITMKEEWHKFIQLLTEFQMRNVDFLYSNLEFILPLPVDTIPETKNFCGPSVTVDASAATKSMNCLARKHSEREQPLKKSQKKKQKKTLVILDDSDLFDTDLDFPDQSISLSSVSSSSNAEESKTG---DEESKARDKGNNPETKKSIPCPPKTTAGKKCSALVSHCLNSLSEFMDNMSFLDALLTDV--REQNKYGRNDFSWTNGKVTSGLCDEFSLESNDGWTSQSSGELKAAAEALSFTKCSSAIS-KALETLNSCKKLGRDPTNDLTFYVSQKRNNVYFSQSAANLDN---AWKRISVIKSVFSSRSLLYVGNRQASIIEYLPTLRNICKTEKLKEQGKSKRRFLHYFEGIHLDIPKETVNTLAADFP---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NDC2-1", "uniprot_id": "A0A8M1NDC2_DANRE", "id": "A0A8M1NDC2-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATMDSSLFPLAVVKIMNSSG-------------------------------------------------------------------------SVCNRRN---------FHAGVLQSEGNPQTQMHPKRNRLKLAKTYR-------------TSDNIVGNNPSHVTGSYESTTFCKGTFFTDAVRTTDDKDNLTQKEHFSQRVQ----------------------NSNKVTSKRTSNNMSVQLVCTPAKREHASSDSS----LKPAIDHFGSNKEGLTRFLQTEIDDGDHLIDQPKMNIGQIQETSKHDPIQNLRSSNNSTSSCREPPNVRTVKEMRLSWRKEIPSE----------------NSCELLKDIQKLNLQFPVQRFFTLLLKKGTSSMEESSALEAEMS-------------------------------------------------------------ENYKHHSDYCVQRKRKLELEDQYRTYKRYRMNKGIRFAIKD----------------FELFSDVLVNPHSKYTNRLSRTKCRQQQTTFCAIVTEPVQNDSVYQNQRLR-------------VDDVLWTDKYQPQQSSEVIGNSASVRQLHSWLKEWKTRADTEERRRRQDERRMKKEAAESWDCGDFVGDAVSIDQVKELCNTVLITGPSGVGKTAAVYACAQELG-----FKVFEVNSSALRCGRLLLSQLTEATQSHQMDLESIKPSAVESESGVINQSQIKPAPVSSTGKEAHRKVTTSPSKETSVCRSDSHNIRNPQPVKLTRFFKLSSK----KSLVKTSDGPERCKHATVEPDRLQKSGSG-CKSERGKESASKNQSRAIPVSLILFEEVDVIFP-EDVGFLTAIKTFMSTSKRPIILTTNDP-LFGARLKGHFDEIH--FRTPSLQTIRSYLQCLCAVENMKTDPEY--MAFLLCQNKGDIRQSILQLQLWVCSGGGSTELQI---LQNTLKCRSWTELKNS---------------RCLEILAEKTGAGLLYFIIGSLFSPKFSSQSFYLQEFSN-------------------------------------PNTKGEKSEGLMLQTSSNVHERKSACRGKTHRPKTISYPYSVKASD-------------------------------------------PSKQTNKLASEP------------RARGQSKSLIFQHVLCIGSFFDNMSFVDACLQKPSLSRTELCKTEALGWMGATLKDSLLDLQREEQIRQYFENSS-QLLAFVEVLSFHRCQTELSGIWTEAARLREKMSSERWEQVMASFSQPFGQKYLATCHCKFCEPRVAQKHRELASILNSSRKICCLRNKRAFFMDYLPTLRSICRSERIKGQHSIRR----SYYLSSLHLPRSTLELMAVDFP---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86BP6-1", "uniprot_id": "ELG1_DROME", "id": "Q86BP6-1", "name": "Enhanced level of genomic instability 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDVNCLTSEHIAPTTTTASPPGTPSKNAATDPVEPTS-PFVLRAPPSAKSKLILQNMEEVLNSVKQKHREKHKRKREEKRRAALMEDQKSTTEEVKAN----AKEKPQPLREKSSQENGLKNGRRRSSPLKSSTPVADNQSIMKHFAKAGKPENVGVSPVSTAKPKPTTN-------------------------VFEFMMNARNRSLGVNEGGAESPADQEIGSEAATPTTKRKLLLQEWNE-----RKGGAKRRLADEARGEFIELQMEQRAKRLRKMLTKTDAKEVTAPSSAPTDPTVKRLRGRPRSRRISSMDAQNQIVESKPPVVKAKDQDPGTEELLSKLSSPTKKRDS--------------LLGYFPKVESPKELAEKVIIAIETPPMETPKRRTLRRKSQQETPIVAESTPSSRPRRSCVGKARYDYDLETSPGKQQKAKPQKADESVEIIDLDNSNPAATP---KKLAPLFVRQLPKPSPDP-------------------SVLKARQAFLQSGVPDKIRQEQIRQKNFDQMYEDSYEVFPRLAHIGCESFGSKNGPLDIP---------------------------FALRAEEEYSEVTKALPANKRRAKASSITSCLPADFTSSKTLNKFNYATLPQLENKRGFVKLWKN-----DFDRFPTFKCYNQMREKYRHFSAIDSAQDTQQMGESLVVTRRTRRSMEQNMAQNEEEAKPPPSAPNGELLFTEKYKPLLFEQVLVNLTPVQELREFLSSWSGNGGSNRNSQ---------------GMDDTFDMSNDSASMGSSSNTMVLVGPSSSGKTNAVFTLANDMN-----FNVLEINAGMKRTGKKLIQELQEATQSHQIRKDGKAG-------GGSSQQLLQKLQK----------------------------------------------------------------------------------SGLKAKAAAVEPPSEVRKSLILIEDADILFDNLDAGFTDAIYTLAASSKRPVIVVATDPNCAHLQRLMQQNIIH--FQAPNALNISRFLAVLSLMENCPIELDE--LISVYLYNQQNLRKTLMELQFYIQSGGDSTRDRTGGGIKSPTKTS-------------------NSRLATVDGSRIHQRFFEFFTSPQNVQYRIPFPVDFSLLRLNL-------------------------------------PDLMASSAMLKEQQAAGGGSRTAAKRKSRSPKKAWLSSATGQKSDG----------------------------------------------------------------------------HSSSLATLASFYDNISVASLMDSDCS---------DRLQWHLSEEIGHLLVEQALQTG-----------------LATKECPYNLFDKPVQRFSICQHLGNG------VLRSDSAKSLDFEPALRSICR----SEKERAGLERKSSRFYHYLRNHTVNVTSFTTDYFDTACSTFQSAAP----------------SSEPTMEAEPKD-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12050-1", "uniprot_id": "ELG1_YEAST", "id": "Q12050-1", "name": "Telomere length regulation protein ELG1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKRHVSLSDILTGNKRKVRR-------------------QDALQITIDDENDTESGTFDARTAKHDDSSVIFLNHS-----------------------------------VVKPIEAVSTNHKSAKEFLMTKRTKEKCDDDDD--DLIVISDKSPKSETNCSKIALSQEHEDDISIISTSRIKSSLLNERASKIKNFLKHETTDTFKRLNSISKLNEIEPPLPLHQS-------------------------------------------------------------------------------------------------------------------------------IFPVGDKELSDRSVDIPLPFRTIPPLNHNFLPSDYESLKDK-------------------NSASCIPVRYQAPVLLGTNIKRNTTLTWPQLFKPVTLKQVLIEPKLK------------------LRIKNWIETSFHTLEKPTLRNRLLNRINPNKQQGSGDELANFIVPDLEEDE-----NLRPDFYRNGEANSSLSEFVPLMILHGNSIGKKTLIQTIMREIAGDDNSYQIYEVNSNMNRSKKDLLDILLDFTTTHYVK---------------------------------------------------------------------------------------------------------------------DSSKRKSDYGLVLFNDVDVLFKEHDRGYWAMISKLCEFSRRPLVLTCKDLSLVPSELIALASEQNSLFHTKKISTSTVYAFLTKYLKSLEIEVCDDWLRDVVKQNNADIRKCLMHLQFWCVDTEADLISSK---NRLPVLTS------------------------TLGSSVKDISQLTDLLSINDVIGQATLNRSMVRQEIDS---------------------------------------TTMTPEKVNTFQDQNLDDEMKLKFDYVIDYKLHLNDPNRQ------------------------------------------------------------------------------PLLPFELNIYQHIQEQLEARYSYVREANHRLDNEYLVNRFKKMTESTLNFLASRIPKYDHLQSARRTR----------NSKKISDILN--QFKGIYNDETLNENAEIDLLSATTQQIKAEINPFVFEIAKS---------DANVKNENKQIFELHSENVSERRYKDLVYQLSQEGVLKNVWFN----------ADPSIVVRKWEHLHSGFSKNK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : .. : :: : . . . : .: . . : . . . : ::. : . . * . : : ..* . :. . .. :. . . . . . .::: .. **. : : .:: ::: *:*:. * : ::. * : * :* : . .*:*:::.*::* * *: : .: ::**:::. .* . : * . . : :. : : : * ::*: :: **:: . : . .: . .: : : . : : :::. . . : . * . : : : : :: .. : .. . : . . . . . ", "identical_positions": 25, "similar_positions": 149, "identity": "1.32%" }, { "cls_id": "homologset.agr.SGD:S000005671", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6VBQ8-1", "uniprot_id": "PNO1_RAT", "id": "Q6VBQ8-1", "name": "RNA-binding protein PNO1", "aln": "----METQNTGTEDGFTPVTHRGG-----------RRAKKRQAEQSSAAGQDGDAGRMDTEEARPAK--------------RPVFPPLSGDQLLTGKEETRKIPVPANRYTPLKENWMKIFTPIVEHLGLQIRFNLKSRNVEIRTC-KDTKDVSALTKAADFVKAFVLGFQVEDALALIRLDDLFLESFEITDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADVKVHILGSFQNIKMARTAICNLILGNPPSKVYGNIRAVASRSADRF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CPS7-1", "uniprot_id": "PNO1_MOUSE", "id": "Q9CPS7-1", "name": "RNA-binding protein PNO1", "aln": "----METQSTGTEDGFTPVTHRGG-----------RRAKKRQAEQSSAAGQDGEAGRMDTEEARPAK--------------RPVFPPLSGDQLLTGKEETRKIPVPGNRYTPLKENWMKIFTPIVEHLGLQIRFNLKSRNVEIRTC-KDTKDVSALTKAADFVKAFVLGFQVEDALALIRLDDLFLESFEITDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADVHVHILGSFQNIKMARTAICNLILGNPPSKVYGNIRAVASRSADRF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRX1-1", "uniprot_id": "PNO1_HUMAN", "id": "Q9NRX1-1", "name": "RNA-binding protein PNO1", "aln": "MESEMETQSARAEEGFTQVTRKGG-----------RRAKKRQAEQLSAAGEGGDAGRMDTEEARPAK--------------RPVFPPLCGDGLLSGKEETRKIPVPANRYTPLKENWMKIFTPIVEHLGLQIRFNLKSRNVEIRTC-KETKDVSALTKAADFVKAFILGFQVEDALALIRLDDLFLESFEITDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADVKVHILGSFQNIKMARTAICNLILGNPPSKVYGNIRAVASRSADRF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6VEU3-1", "uniprot_id": "PNO1_DANRE", "id": "Q6VEU3-1", "name": "RNA-binding protein PNO1", "aln": "----MESVSDSTAEVSATMDCDGNTEA-------FEKVKSKKREKCKRAAAEMDTQTEESSSSAPVK--------------RPHFPALSGDQLGGGVDEMRKVPVPSHRYTPLKENWLKIFTPIVENLQLQVRFNLKTRQVEIKTC-KETQDIGALTRAADFVKAFVLGFQVEDALALIRLDELFLETFDVTDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTKTRIVLADTKIHILGSFQNIKMARTAICNLILGSPPSKVYGNLRAVATRSAERF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VR89-1", "uniprot_id": "PNO1_DROME", "id": "Q9VR89-1", "name": "RNA-binding protein pno1", "aln": "----MEAENIR-ADAFEPAKRATK------------RGASGGGQQDVEMQVDEATGIEG--QVLGSS--------------RASAPPKAKR----ARSELRKVSVPPHRYSSLKEHWMKIFTPVVEHMKLQIRFNMKARQVELRVG-PETPDIANLQRGADFVRAFLCGFEVDDALALLRLEDLFVESFEIKDVKTLRGDHQSRAIGRLAGKGGRTKFTIENVTKTRIVLADSKIHILGSYQNIQLARRAVCNLILGSPPSKVYGNLRAVASRLSERM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99216-1", "uniprot_id": "PNO1_YEAST", "id": "Q99216-1", "name": "Pre-rRNA-processing protein PNO1", "aln": "----MVAPTALKKATVTPVSGQDGGSSRIIGINNTESIDEDDDDDVLLDDSDNNTAKEEVEGEEGSRKTHESKTVVVDDQGKPRFTSASKTQGNKIKFESRKIMVPPHRMTPLRNSWTKIYPPLVEHLKLQVRMNLKTKSVELRTNPKFTTDPGALQKGADFIKAFTLGFDLDDSIALLRLDDLYIETFEVKDVKTLTGDHLSRAIGRIAGKDGKTKFAIENATRTRIVLADSKIHILGGFTHIRMARESVVSLILGSPPGKVYGNLRTVASRLKERY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . . :. : :. .. . * **: ** :* :.*:: * **:.*:**:: **:*:*:*::.**::. * * . * :.***::** **:::*::**:**::*::*:*::.***.* *** ******:***.*:***:***.*:******* ::****.: :*::** :: .****.**.*****:*:**:* :* ", "identical_positions": 93, "similar_positions": 73, "identity": "33.45%" }, { "cls_id": "homologset.agr.SGD:S000005674", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V8Z3-1", "uniprot_id": "G3V8Z3_RAT", "id": "G3V8Z3-1", "name": "G-patch domain and KOW motifs-containing protein", "aln": "MAG----------RES--PPPAAASTAPISFGFTRTSVRRRLADLGDSEGQAPEKKDFLATVEGRELQSVNPPEAPKELVIPLIQ-NGSRRQLLSKNPKPS----ETSTVLTSDGVLSQAVKELIE----ESKKSLEERENAG-VDPTLTIPMIQKGCTPIGEGTYSEPQAETVPE---EADYEAVPVEAYGLAMLRGMGWKPGKGIGNTFSQVVKPRVNSIRPKGLGLGANLMETQALASTGSHHPPRPDGDREKDKEGQPQGLMHGGAVVVLSGPYRGLYGKVEGLDPDNVRAMVRLAVGNRVVNVSEYCLRPVSQQEFDSHTSKPGHVSKTSTE-------QQHRATGTASSVKALQNQEDSKRRQKDSE--KKRKH---SPDRRDGPVPKTEKAAPRNKHWLHRDLRVRFIDKVHKGGRYYNTKMTIEDVLSPGTCVCRTDEGRVLEGVKEGMLETLVPRGEGHRVMVVLG--PHAGKVGLLLRRDRAQSHAMVQLGR-ENQVVELHYDAICQYMGPGDSDED----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q56A08-1", "uniprot_id": "GPKOW_MOUSE", "id": "Q56A08-1", "name": "G-patch domain and KOW motifs-containing protein", "aln": "MAG----------RES--PPPSAPSMAPISFGFTRTSVRRRLADLGDSERQAPEEKDFLATVEGRKLQSVNPPEAPKELVIPLIQ-NGSRRQPLSKNPKPSS---ETSTVLMSDGVLSQAVKELIE----ESKKSLEERENAG-VDPTLTIPMIQKGCTPIEEGSDSEPQAETVPE---EADYEAVPVEAYGLAMLRGMGWKPGKGIGNTFSQVVKPRVNSIRPKGLGLGANRMEAQDLASVGSHHPPRPDGDRENDKEGQPQGLMHGRAVVVLSGPYRGLYGKVEGLDPDNVRAMVRLAVGNRIVTVSEYCLRPVSQQEFDSHTSKPGHVSQTSTE-------QQNRATGTASSLKAAQNQEDSKRRQKGSE--KKRKH---SPDRQDGPVPKTEKAAPRNKHWLHRDLRVRFIDKLHKSGRYYNTKMTIEDVLSPDTCVCRTDEGRVLEDVREDMLETLIPKGEGHRVMVVLG--PHAGKVGLLRSRDRAQSHALVQLRR-ENQVVELHYNAICQYMGPGDSDED----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92917-1", "uniprot_id": "GPKOW_HUMAN", "id": "Q92917-1", "name": "G-patch domain and KOW motifs-containing protein", "aln": "MAD----------SKEGVLPLTAASTAPISFGFTRTSARRRLADSGDGAGPSPEEKDFLKTVEGRELQSVKPQEAPKELVIPLIQ-NGHRRQPPARPPGPS-----TDTGALADGVVSQAVKELIA----ESKKSLEERENAG-VDPTLAIPMIQKGCTPSGEGADSEPRAETVPE---EANYEAVPVEAYGLAMLRGMGWKPGEGIGRTFNQVVKPRVNSLRPKGLGLGANLTEAQALTPTGPSRMPRPDEEQEKDKEDQPQGLVPGGAVVVLSGPHRGLYGKVEGLDPDNVRAMVRLAVGSRVVTVSEYYLRPVSQQEFDKNT--------LDLR-------QQN---GTASSRKTLWNQELYIQ-QDNSE--RKRKH---LPDRQDGPAAKSEKAAPRSQHWLHRDLRVRFVDNMYKGGQYYNTKMIIEDVLSPDTCVCRTDEGRVLEGLREDMLETLVPKAEGDRVMVVLG--PQTGRVGHLLSRDRARSRALVQLPR-ENQVVELHYDAICQYMGPSDTDDD----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90X38-1", "uniprot_id": "GPKOW_DANRE", "id": "Q90X38-1", "name": "G-patch domain and KOW motifs-containing protein", "aln": "MASPERYQERESLKKDISQDDGGKKAAPISFGFSKTLIKVKSGK--------AEERDYLVEVEGKELKGTKPVEKPKELIIPLIHKNRWYRQDAERADKTSEEKTEEPSQVKQDTVESQAVKELIE----ESQKYQDRWKNGPQSDPNFAIPLLMQNQVPDGFEDGDKVNVDLRPESSTEADYERVPVEAYGLAMLKGMGWKQEEGIGRTFKQDVKPIEHQLRPKGLGLGADRSAIKDLEPGVPKRPPKPGD--EKGKEEEALVLGPGGCVQVLAGAHKDLYGKIEGVDPDNGRVVVKLAIGGKTVTIIQHSIKLVTRKEYDKYSKDLSRLSKAHKDKEREKEREQKREQEQRLNGKDERGKTDRSREKDRDQ--KKRKHRESSTDREKPPPAKESRSSPPAPSWLQRDLRVRFIDKAFKGGKYYNSKMRVEDVLTPHTCVCRTEEGRMLDDIRQKMLETIVPKNDSDYIMVVLG--EHRGQVGRILKRDREKCRAMVQLDRYEERVFTLDYDTICHYVGGTDH-------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02521-1", "uniprot_id": "SPP2_YEAST", "id": "Q02521-1", "name": "Pre-mRNA-splicing factor SPP2", "aln": "-------------------------MSKFSLKLGSKTLKKNISK---------------KTKKKNSLQKAN-----------LFDWDDAETASLSHKPQSK--------------IKIQSIDKFDL----DEESSSKKK-------------LVIKLSENADTKKNDAPLVEYVTE----KEYNEVPVEEFGDALLRGMGWESD---------------------------------------SEQDSKGDKTQSRNKD----------------------VSNVSQIHPDGLGIGAKLN---KAINVEEASFMPVVK-------------------------------------------IDKITGTKVDDD--KKNKS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VES0-1", "uniprot_id": "Q9VES0_DROME", "id": "Q9VES0-1", "name": "Spp2/MOS2 G-patch domain-containing protein", "aln": "-----------------------MEAKKISFGFSKLSKKPNILP--SKQPKEESKVELIKCLEGNEIMPVDEKVEAAPLTIKMIGMQKTSSALASLMRRRAVLLGEEEPDPEEVTPVAQSIAEVTAGGPTESLEQRAARELISAIQNNGAEGLDDQKLVLPALSADELPLDGAKEAT--LDDYDNIPIQQFGLAMLRGMGWVDPPPKKKGSGPIDDAP--FLRPKGMGLG-------------ADKALKPKALLVQPEKNEVLEIKKQAYVRILGGKQKDQYGQIQGFDDHAGRVIVKMAIGGAKEAFNEFLCQPVSRKEYSQYGKCINTAKYEEFKKNENEHGQIIVKQENPSGRRDRDRREEIRSDRDEAQNQKSSKPGDQRSSKEDYRMKCKEEDKRSYKYEDKKTYKDEHRRTYKDERKSYKEAKSNKEEVDREKKYVRSGSSSVSKREERERRRSPSPRGRSPSKSKREDRDQKRSQSPRSTRRTKSSSDEADDTGESTESDSDSAYERRKHKKKSSSHKSRKHSKKSKNKSRKADNDSSLESDDSLGENHRRHHSKHKKKTKRSKHVRSRTRSRSRDRQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: : : . : ..: .. :: : *:: :. :. . : : . :*: :*:: :* *:*:**** . : : . :. .::. .. . .:: . : * : : : :. * ", "identical_positions": 13, "similar_positions": 55, "identity": "2.22%" }, { "cls_id": "homologset.agr.SGD:S000005675", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BTP0-1", "uniprot_id": "PIGZ_MOUSE", "id": "Q8BTP0-1", "name": "GPI alpha-1,2-mannosyltransferase 4", "aln": "-----------------------------MMVAAQVIWGSFSLLRVLWCLLPQTGYIHPDEFFQSPEVMAEDILGVQATRPWEFYPSSSCRTVVFPLLTSGSTFWLLRLWEELG---LWPGLVSGYMLLVGPRFLLTALSFALDWAVYDLAPLWGADRWNALCLLSGSYVTLVFYTRTFSNTIEGLLFTWLLVLVSPGVVRS------------PTSKKPTPGPRWHRYLLG---------------VILAAGFFNRPTFLAFALAPLSLWGIHRASELGG-IRALIQEALVLLPGAALAAVLCVATDSWYFSSLSR---------STGVFLTPANFLYYNLDPQNLARHGTHARLTHLAVNGFLLFGVLHAQALQAAWQQLHACLRASPQTGLSRVRGARGLLSSSKSYLLLFYFTPLLLLSAFSHQEARFLIPLLVPLVL-LCSPQTQP-----IPWKGTLVLFNILG------------------------ALIFGCLHQGGLVPGL----KYLEQIVHTPDLSGTTTHYTLLFTHTYMPPQHLLHLSG---------------LGSPVEVVDMGGAEDRVLCQALNNFSRQPACQLAG-EPWPCRLFVVTPG--------TNRHALEKCRFPLKNETLLFPHLTLEDPPALS----------------------------------SLLSGAWRKHLSLHVIELETPVVTKQPKAQP---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86VD9-1", "uniprot_id": "PIGZ_HUMAN", "id": "Q86VD9-1", "name": "GPI alpha-1,2-mannosyltransferase 4", "aln": "MQICGSSVASVAAGTSFQVLGPVCWQQLDLKMAVRVLWGGLSLLRVLWCLLPQTGYVHPDEFFQSPEVMAEDILGVQAARPWEFYPSSSCRSVLFPLLISGSTFWLLRLWEELG---PWPGLVSGYALLVGPRLLLTALSFALDGAVYHLAPPMGADRWNALALLSGSYVTLVFYTRTFSNTIEGLLFTWLLVLVSSHVTWG------------PTRKEPAPGPRWRSWLLG---------------GIVAAGFFNRPTFLAFAVVPLYLWGTRGATNPG--LKSLTREALVLLPGAALTAAVFVATDSWYFSSPAT---------SRNLVLTPVNFLHYNLNPQNLARHGTHARLTHLAVNGFLLFGVLHAQALQAAWQRLQVGLQASAQMGLLRALGARSLLSSPRSYLLLLYFMPLALLSAFSHQEARFLIPLLVPLVL-LCSPQTQP-----VPWKGTVVLFNALG------------------------ALLFGCLHQGGLVPGL----EYLEQVVHAPVLPSTPTHYTLLFTHTYMPPRHLLHLPG---------------LGAPVEVVDMGGTEDWALCQTLKSFTRQPACQVAG-GPWLCRLFVVTPG--------TTRRAVEKCSFPFKNETLLFPHLTLEDPPALS----------------------------------SLLSGAWRDHLSLHIVELGEET------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MT80-1", "uniprot_id": "PIGZ_DROME", "id": "Q8MT80-1", "name": "GPI mannosyltransferase 4", "aln": "------------------MRLTTLWQNRSPGDRHLSTYFCFAAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLPFALLRIPWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFRICRLYGLRFEIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEFLEEKYDKAESISERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRPTFLLFGAPMVFFWLLRGMGTRSITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHLSIDNFVFTPWNFIKANLDSAQTASHGVHPCYVHLMVNMPMLFNVLALASLGAFAQLLLRFFRAEYQV-LPRFQSIVSLMSG-------AIFVPLFFLSLINHQEPRFLLPVTFPLIL-LHAPKLITGFSAKYPFQKDHPLLRLFYDKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGVYP-------LAADISHVIATKPAATHVHLITSHIYSLPLHLINIPSSRVLHFNRLTHQRYRRPRDFYMYEYGGLPLDSLLQKVKLISGSCEVKKSGPSRRRYKLYLAIPASLSADLHEALVHSNASSYLNFELLKVFYPHLSTEAFPHLQGRHPCDVDAPHWAHDDLRGTCSAEQLPAFSFAYLNKQFSSFVHQLGLALYEIDVTRNKPRSVVIKKASMTETAA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04174-1", "uniprot_id": "SMP3_YEAST", "id": "Q04174-1", "name": "GPI mannosyltransferase 4", "aln": "--------------------------------MMRYQWWLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGPLLLVYGPLFTILESFPEIQ---DNPALILYSMRLQNYVMYLLCYHFLIPKLIRDER---KAVQFIKKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEK----------------NIQRSNFKNSVILG---------------LIFSFGVFNRVTFPAFIFLPCLILFWK-------FYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKG------------FVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYK--------------LDKLSTYAIISG------------LLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKKIFKGTWLLFNIIM------------------------AFIMGISHQAGIIQFLGDYFHFRTEQMGVHIWWKTYSPPTWMYMSNNLTVSSLINTQDG--------------IESIDEVAFSVGNHHVIDLKGCDLPLLTETIRRLRLNGSITPLTLVTPN----SMTSELKKLKRDGTINLIPKRNYLFHLDLDHLDFND-------------------------------------FTTFKPGLTVYSIELL---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : .*:****.**. *::: : : :: : .*** . . *: : : : . * *: : : * : : *:: .: *:****::* * ::. : . . * * *.*** ** * : : : :: : : : *: :. ..:** * : **: : ** *. .** ** :.. : :: : : . .::*. * :** :.*** ***:*: *: * . . :: *:. : ::::* **.*: : . : : : *:: . : * : . : * :. * : . : : ** : . :: * : *: ", "identical_positions": 71, "similar_positions": 117, "identity": "9.73%" }, { "cls_id": "homologset.agr.SGD:S000005676", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XFW4-1", "uniprot_id": "Q5XFW4_RAT", "id": "Q5XFW4-1", "name": "Large ribosomal subunit protein uL13m", "aln": "----------------MWYLLDGKMQ--PPGKLAAIASNKLQGLHKPVYHQLSDCGDHVVIINTRHIAFSGNKWEQKVYSSHTGYPGGFRQVTAAQLHL-KDPVAIVKLATYGMLPKNLHRRTMMQRLHLFPDEDIPEDILKNLVEELPQPRRVPKRLDEYTQEEIEAFPRVWAPPDDFRI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D1P0-1", "uniprot_id": "RM13_MOUSE", "id": "Q9D1P0-1", "name": "Large ribosomal subunit protein uL13m", "aln": "MSSFSRAPQQWATFARMWYLLDGKMQ--PPGKLAVIASNKLQGLNKPVYHQLSDCGDHVVIINTRHIAFSGNKWEQKVYSSHTGYPGGFRQVTAAQLHR-KDPVAIVKLAIYGMLPKNLHRRTMMQRLHLFPDEDIPEDILKNLVEELPQPRRVPKRLDEYTQEEIEAFPRVWTPPDDFRM-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYD1-1", "uniprot_id": "RM13_HUMAN", "id": "Q9BYD1-1", "name": "Large ribosomal subunit protein uL13m", "aln": "MSSFSRAPQQWATFARIWYLLDGKMQ--PPGKLAAMASIRLQGLHKPVYHALSDCGDHVVIMNTRHIAFSGNKWEQKVYSSHTGYPGGFRQVTAAQLHL-RDPVAIVKLAIYGMLPKNLHRRTMMERLHLFPDEYIPEDILKNLVEELPQPRKIPKRLDEYTQEEIDAFPRLWTPPEDYRL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJ38-1", "uniprot_id": "RM13_DROME", "id": "Q9VJ38-1", "name": "Large ribosomal subunit protein uL13m", "aln": "-MSIAKRVQQWATFARTWHIYDCTWQ--NPFESAKLVKTHLLGLQKPIYHPMNDCGDHVVLINTREIALPGDEWVKRVYFHHTGYPGGASWTLAWQLHE-KDPTMVMKKAVYNSMRGNLQRRHTMQRLHLFADDQVPEEILQNVTNQIRTPRSIPQRLDHIDKETLENFPNIMDYPKDYILR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12487-1", "uniprot_id": "RM23_YEAST", "id": "Q12487-1", "name": "Large ribosomal subunit protein uL13m", "aln": "--MSQKIGHSGLAFARLWHHVDVARDKRTLGRLASAIAITLIGRHKPVYHPSQDCGDYVVVTNCQKIRVTGKKFEQKTYWSHSGRPGQLKLQTMNKVVADKGFGEILKKAVSGMLPKNKLRKQRLDRLKVFDGS--ENPYKQNITAFAHEQSSIPEPLKESIFNQLK---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: * : . * * * :**:** .****:**: * :.* ..*.:: ::.* *:* ** :: :. ::* * . : * *: ::**::* .. : :*:. :*: *.. : :. ", "identical_positions": 33, "similar_positions": 45, "identity": "18.13%" }, { "cls_id": "homologset.agr.SGD:S000005677", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V8Y5-1", "uniprot_id": "G3V8Y5_RAT", "id": "G3V8Y5-1", "name": "DNA-directed RNA polymerase subunit beta", "aln": "-MYDADEDMQYDEDD---DEITPDLWQEACWIVISSYFDEKGLVRQQLDSFDEFIQMSVQRIVEDAPPIDLQAEAQHASGEVEEPPRYLLKFEQIYLSKPTHWERDGAPSPMMPNEARLRNLTYSAPLYVDITKT--------------VIKEGEEQLQTQHQKTFIGKIPIMLRSTYCLLNGLTDRDLCELNECPLDPGGYFIINGSEKVLIAQEKMATNTVYVFAKKD-SKYAYTGECRSCLENSSRPTSTIWVSMLARGGQGAKKSAIGQRIVATLPYIKQEVPIIIVFRALGFVSDRDILEHIIYDFEDPEMMEMVKPSLDEAFVIQEQNVALNFIGSRGAKPGVTKEKRIKYAKEVLQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLAALGRRELDDRDHYGNKRLDLAGPLLAFLFRGMFKNLLKEVRIYAQKFIDRGKDFNLELAIKTRIISDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFASTLSHLRRLNSPIGRDGKLAKPRQLHNTLWGMVCPAETPEGHAVGLVKNLALMAYISVGSQPSPILEFLEEWSMENLEEISPAAIADATKIFVNGCWVGIHKDPEQLMNTLRKLRRQMDIIVSEVSMIRDIREREIRIYTDAGRICRPLLIVE------KQKLLLKKRHIDQLKEREYN----------NYSWQDLVASGVVEYIDTLEEETVMLAMTPDDLQ-EKEVA----------------YCSTYTHCEIHPSMILGVCASIIPFPDHNQSPRNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSIVAIASYTGYNQEDSVIMNRSAVDRGFFRSVFYRSYKEQESKKGFDQEEVFEKPTRETCQGMRHAIYDKLDDDGLIAPGVRVSGDDVIIGKTVTLPENEDELESTNRRYTKRDCSTFLRTSETGIVDQVMVTLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMPFTCEGITPDIIINPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPFNDAVNVQKISNLLSDYGYHLRGNEVLYNGFTGRKITSQIFIGPTYYQRLKHMVDDKIHSRARGPIQILNRQPMEGRSRDGGLRFGEMERDCQIAHGAAQFLRERLFEASDPYQVHVCNLCGIM-AIANTRTHTYECRGCRNKTQISLVRMPYACKLLFQELMSMSIAPRMMSV-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30876-1", "uniprot_id": "RPB2_HUMAN", "id": "P30876-1", "name": "DNA-directed RNA polymerase II subunit RPB2", "aln": "-MYDADEDMQYDEDD---DEITPDLWQEACWIVISSYFDEKGLVRQQLDSFDEFIQMSVQRIVEDAPPIDLQAEAQHASGEVEEPPRYLLKFEQIYLSKPTHWERDGAPSPMMPNEARLRNLTYSAPLYVDITKT--------------VIKEGEEQLQTQHQKTFIGKIPIMLRSTYCLLNGLTDRDLCELNECPLDPGGYFIINGSEKVLIAQEKMATNTVYVFAKKD-SKYAYTGECRSCLENSSRPTSTIWVSMLARGGQGAKKSAIGQRIVATLPYIKQEVPIIIVFRALGFVSDRDILEHIIYDFEDPEMMEMVKPSLDEAFVIQEQNVALNFIGSRGAKPGVTKEKRIKYAKEVLQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLAALGRRELDDRDHYGNKRLDLAGPLLAFLFRGMFKNLLKEVRIYAQKFIDRGKDFNLELAIKTRIISDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFASTLSHLRRLNSPIGRDGKLAKPRQLHNTLWGMVCPAETPEGHAVGLVKNLALMAYISVGSQPSPILEFLEEWSMENLEEISPAAIADATKIFVNGCWVGIHKDPEQLMNTLRKLRRQMDIIVSEVSMIRDIREREIRIYTDAGRICRPLLIVE------KQKLLLKKRHIDQLKEREYN----------NYSWQDLVASGVVEYIDTLEEETVMLAMTPDDLQ-EKEVA----------------YCSTYTHCEIHPSMILGVCASIIPFPDHNQSPRNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSIVAIASYTGYNQEDSVIMNRSAVDRGFFRSVFYRSYKEQESKKGFDQEEVFEKPTRETCQGMRHAIYDKLDDDGLIAPGVRVSGDDVIIGKTVTLPENEDELESTNRRYTKRDCSTFLRTSETGIVDQVMVTLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMPFTCEGITPDIIINPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPFNDAVNVQKISNLLSDYGYHLRGNEVLYNGFTGRKITSQIFIGPTYYQRLKHMVDDKIHSRARGPIQILNRQPMEGRSRDGGLRFGEMERDCQIAHGAAQFLRERLFEASDPYQVHVCNLCGIM-AIANTRTHTYECRGCRNKTQISLVRMPYACKLLFQELMSMSIAPRMMSV-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CFI7-1", "uniprot_id": "RPB2_MOUSE", "id": "Q8CFI7-1", "name": "DNA-directed RNA polymerase II subunit RPB2", "aln": "-MYDADEDMQYDEDD---DEITPDLWQEACWIVISSYFDEKGLVRQQLDSFDEFIQMSVQRIVEDAPPIDLQAEAQHASGEVEEPPRYLLKFEQIYLSKPTHWERDGAPSPMMPNEARLRNLTYSAPLYVDITKT--------------VIKEGEEQLQTQHQKTFIGKIPIMLRSTYCLLNGLTDRDLCELNECPLDPGGYFIINGSEKVLIAQEKMATNTVYVFAKKD-SKYAYTGECRSCLENSSRPTSTIWVSMLARGGQGAKKSAIGQRIVATLPYIKQEVPIIIVFRALGFVSDRDILEHIIYDFEDPEMMEMVKPSLDEAFVIQEQNVALNFIGSRGAKPGVTKEKRIKYAKEVLQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLAALGRRELDDRDHYGNKRLDLAGPLLAFLFRGMFKNLLKEVRIYAQKFIDRGKDFNLELAIKTRIISDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFASTLSHLRRLNSPIGRDGKLAKPRQLHNTLWGMVCPAETPEGHAVGLVKNLALMAYISVGSQPSPILEFLEEWSMENLEEISPAAIADATKIFVNGCWVGIHKDPEQLMNTLRKLRRQMDIIVSEVSMIRDIREREIRIYTDAGRICRPLLIVE------KQKLLLKKRHIDQLKEREYN----------NYSWQDLVASGVVEYIDTLEEETVMLAMTPDDLQ-EKEVA----------------YCSTYTHCEIHPSMILGVCASIIPFPDHNQSPRNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSIVAIASYTGYNQEDSVIMNRSAVDRGFFRSVFYRSYKEQESKKGFDQEEVFEKPTRETCQGMRHAIYEKLDDDGLIAPGVRVSGDDVIIGKTVTLPENEDELESTNRRYTKRDCSTFLRTSETGIVDQVMVTLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMPFTCEGITPDIIINPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPFNDAVNVQKISNLLSDYGYHLRGNEVLYNGFTGRKITSQIFIGPTYYQRLKHMVDDKIHSRARGPIQILNRQPMEGRSRDGGLRFGEMERDCQIAHGAAQFLRERLFEASDPYQVHVCNLCGIM-AIANTRTHTYECRGCRNKTQISLVRMPYACKLLFQELMSMSIAPRMMSV-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1N6S0-1", "uniprot_id": "A0A8M1N6S0_DANRE", "id": "A0A8M1N6S0-1", "name": "DNA-directed RNA polymerase subunit beta", "aln": "-MYDQDEDIQYDEDD---DEITPDLWQEACWIVISSYFDEKGLVRQQLDSFDEFIQMSVQRIVEDAPPIDLQAEAQHTSGEVEEPPRYLLKFEQIYLSKPTHWERDGAPSPMMPNEARLRNLTYSAPLYVDITKT--------------IIKDGEEQQQTQHQKTFIGKIPIMLRSTYCLLSGLTDRDLCELNECPLDPGGYFIINGSEKVLIAQEKMATNTVYVFAKKD-SKYAYTGECRSCLENSSRPTSTIWVSMMARGGQGVKKSAIGQRIVSTLPYIRQEVPIIIVFRALGFVSDRDILEHIIYDFDDPEMMEMVKPSLDEAFVIQEQNVALNFIGSRGAKPGVTKERRIKYAKEVLQKEVLPHVGVSDFCETKKAYFLGYMVHRLLLAALGRRELDDRDHYGNKRLDLAGPLLAFLFRGMFKNLLKEIRIYAQKFIDRGKDFNLELAIKTRIISDGLKYSLATGNWGDVKKAHQARAGVSQVLNRLTFASTLSHLRRVNSPIGRDGKLAKPRQLHNTLWGMVCPAETPEGHAVGLVKNLALMAYISVGSQPSPILEFLEEWSMENLEEISPAAIADATKIFVNGCWVGIHKDPEQLMNTLRKLRRQMDIIVSEVSMIRDIREREIRIYTDAGRICRPLLIVE------KQKLLLKRRHIDQLKEREYN----------NYSWQDLVASGVVEYIDTLEEETVMLAMTPDDLQ-EKGVA----------------YCSTYTHCEIHPSMILGVCASIIPFPDHNQSPRNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSIVAIASYTGYNQEDSVIMNRSAVDRGFFRSVFYRSYKEQESKKGFDQEEIFEKPTRETCQGMRHAIYDKLDDDGLIAPGVRVSGEDVIIGKTVTLPENDDELDSTNRRYTKRDCSTFLRTSETGIVDQVMVTLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMPFTCEGITPDIIINPHAIPSRMTVGHLIECLQGKVSANKGEIGDATPFNDAVNVQKVSNLLSEYGYHLRGNEVLYNGFTGRKLTSQIFVGPTYYQRLKHMVDDKIHSRARGPVQILNRQPMEGRSRDGGLRFGEMERDCQIAHGAAQFLKERLFEASDPYQVHVCNLCGLM-AIANTRTHTYECRGCRNKTQISLVRMPYACKLLFQELMSMSIAPRMMTS-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08266-1", "uniprot_id": "RPB2_DROME", "id": "P08266-1", "name": "DNA-directed RNA polymerase II subunit RPB2", "aln": "MMYDNEEELYEEENA---EEISHELWQEACWIVINAYFDEKGLVRQQLDSFDEFIQMSVQRIVEDSPAIELQAEAQHTSGEVETPPRFSLKFEQIYLSKPTHWEKDGSPSPMMPNEARLRNLTYSAPLYVDITKT--------------KNVEGLDPVETQHQKTFIGKIPIMLRSTYCLLSQLTDRDLTELNECPLDPGGYFIINGSEKVLIAQEKMATNTVYVFSMKD-GKYAFKTEIRSCLEHSSRPTSTLWVNMMARGSQNIKKSAIGQRIIAILPYIKQEIPIMIVFRALGFVADRDILEHIIYDFDDPEMMEMVKPSLDEAFVVQEQNVALNFIGARGARPGVTKDKRIKYAKEILQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLASLGRRELDDRDHYGNKRLDLAGPLLAFLFRGLFKNLMKEVRMYTQKFIDRGKDFNLELAIKTNIITDGLRYSLATGNWGDQKKAHQARAGVSQVLNRLTFASTLSHLRRVNSPIGRDGKLAKPRQLHNTLWGMLCPAETPEGAAVGLVKNLALMAYISVGSQPSPILEFLEEWSMENLEEIAPSAIADATKIFVNGCWVGIHRDPEQLMATLRKLRRQMDIIVSEVSMIRDIRDREIRIYTDAGRICRPLLIVE------NGSLLLKKTHVEMLKERDYN----------NYSWQVLVASGVVEYIDTLEEETVMIAMSPYDLKQDKDYA----------------YCTTYTHCEIHPAMILGVCASIIPFPDHNQSPRNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPMKPLVTTRSMEYLRFRELPAGINSIVAILCYTGYNQEDSVILNASAVERGFFRSVFYRSYKDSENKRVGDQEENFEKPHRGTCQGMRNAHYDKLDDDGIIAPGIRVSGDDVVIGKTITLPENDDELDSNTKRFSKRDASTFLRNSETGIVDQVMLTLNSEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMAFTCEGLAPDIIINPHAIPSRMTIGHLIECLQGKLGSNKGEIGDATPFNDAVNVQKISTFLQEYGYHLRGNEVMYNGHTGRKINAQVFLGPTYYQRLKHMVDDKIHSRARGPVQILVRQPMEGRARDGGLRFGEMERDCQISHGAAQFLRERLFEVSDPYRVHICNFCGLI-AIANLRNNTFECKGCKNKTQISQVRLPYAAKLLFQELMSMNIAPRLMVT-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08518-1", "uniprot_id": "RPB2_YEAST", "id": "P08518-1", "name": "DNA-directed RNA polymerase II subunit RPB2", "aln": "MSDLANSEKYYDEDPYGFEDESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIICEDSTLILEQLAQHTTESDNISRKYEISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKRTYEAIDVPGRELKYELIAEESEDDSESGKVFIGRLPIMLRSKNCYLSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSALEKGSRFISTLQVKLYGREGSSART------IKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGTALGIKKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTVEEAHDFNMKLAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINP-EVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDIEGGFEDVEEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPAEANEENDLDVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPISPDEEELGQRTAYHSKRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDIT-VEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDRSRDF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: :*: :: : : * .* **.::* ***** ******::*:: ::* *: : ..: *: ***:: . : . :: :.* :**::** * ** . .: *:**********: *:**:.* . ::: *.***::******. * *. *: ** :*:***:* *****************: * * * ** . :. * **.**:.** **: *.: .* ... :. * : ****:*::**:*:*****::.* :***** **.:* :*:**:**.:::.**:*:::.**:*** **: *:.*::**:***::****.***: : *::**:*****::****.:*.*:: *****:*:*********** **: :**:* *:: * *: ::..:***::***::. *:.**:*:*******: *** .:********** *::******** *:***************** **::******** * ******:**: ****::* **: **.**.** **: * .***::**** * *:*::* :** ***.***: ** *********::*::*:*****: ***:*** : .* ::: *: * :*: :*:*. *: .*:*****: ***::::** * **: : :.:*:*******:*****.****************************::**::*****:*::**** *** ***:****:******* *:**** .*:*******:*:* *:::**:***:*:*** :.*.* . * **** * . *::. *:******:****:****:**:**** .:. :::** . . .:***.** **.:*.******::* *.:* ** *:***:.:***************** ** **:***.**.**:.**:************:.****** .*:.: .*: ***:**.* . *: :*.:* ::**: ** **:***.**:*: :*:*.********:********:*****:*:* ***:***:************** *:****.**:***:*.**.::**:*.:**:: .**: . : :**:** ** :* :::***.********:*.*:**: ", "identical_positions": 655, "similar_positions": 322, "identity": "53.17%" }, { "cls_id": "homologset.agr.SGD:S000005680", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C341-1", "uniprot_id": "SUCO_MOUSE", "id": "Q8C341-1", "name": "SUN domain-containing ossification factor", "aln": "--MKKYRRALALVSCLSLCSLVWLPSWHVCCKESSSASTS-YYSQDDNCAIGSEDTQFQKKNEREEPSNAELS------GKSNSYLTISPEGNKIKDDYTVDVQDLET-TKLSLPVVEALPTVDLHEESSSVVVGSETIENSSSSSTSERTPVSELDEVEKSGTL----------SIAKPGEVEQPEADCDAGEAPDADAPVEQPAFVS--------------------------------PPESLVGQHIENVSSSHGKEKVTKSEFESKVSVSEQDGGD-----------------------PKSALNTSDTLKNESSDYTKPGETDPTSVTSPKDPEDIPTFDEWKKKVMEVEKEKSQSLHPSSNGGPHATKKVQKN-------------RNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCST-KIWFVIELCEPIQVKQFDIANYELFSSTPKDFLVSISDRYPTNK--WIKLGTFHGRDERNVQSFPLDEQMYAKYVKMFIKYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYQSERQELFDEDYDYPLDYNTVEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATTEPKMTESTRVSTPVPSPEYVIKEVHTHDREPSTSDPPKESPIVQLVQEEEEEASPSTVTLLGSGEQEDESSSWFESETHILCSELTSICCISSFSEYIYKWCSVRIALYRQRSRT-VSKGKDF-VPPQPSLLLPVESVEVSVPQPPSGDVDSENMEREAETVDLDDLSS-VHQGHLINHTVDTIELEPSYPQTLSQSLLLDVTPEMNSLSKVEGSESVKSEGGYIPSQLMTQESSVEFDDKTEKKTESFSSAEKLSVIYETSKVNEVMDNTVKEDILSTEVVTKFPET-----VVPPPMNTATVPEGESVETKPSIADTLKHTVTPVMDP-SLPEVKEDEQSPEDALLRGLQRTATDFYAELQNSTDLGYGNGNLVHGSNQKESVFMRLNNRIK----------------------ALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQT---------EAIHLLQAQLTNMTQLVSN-----------LSATVAELKREVSDRQSYLVMSLVLCVVLGLMLCMQRCRTTSQ----------FDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLIRSKSLQFTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKTEKIETIKPADPLHPIANGDIKGRKPFTNQRDFSNMGEVYHSSYKGPPSEGSSE-----TSSQSEESYFCGISACTSLCNGQTQKTKTEKRALKRRRSKVQDQGKLIKALIQTKSGSLPSLHDIIKGNKEITVGAFGVTAVSGHI---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q710E6-1", "uniprot_id": "SUCO_RAT", "id": "Q710E6-1", "name": "SUN domain-containing ossification factor", "aln": "--MKKYRRALALVSCLSLCSLVWLPSWHVCCKESSSASTS-YYSQDDNCAVGSEDIQFQKKNEREEPSNAKVS------EKSNSYLTISPEENKLKDDYTVDECKIWKQSKLSLPVVEALPTVDSHEESSSVVVGSENIENSSSSSTSETSPISKLDEIENSGTL----------SVAKPGDTEQPEADCDAGEAADADASVEQPAFVS--------------------------------APESLVGQHIENVSSSHGKEKVTKSEFESKVSVSEQDGGD-----------------------PKSALNASDTLKNESSDYTKPRETDPTSVTSPKDPEDIPTFDEWKKKVMEVEKEKSQSLHPSSNGGPHATKKVQKN-------------RNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCST-KIWFVIELCEPIQVKQFDIANYELFSSTPKDFLVSISDRYPTNK--WIKLGTFHGRDERTVQSFPLDEQMYAKYVKMFIKYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYQSERQELFDEDYDYPLDYNTVEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGDKSISENATATTEPKMPESTGVSTPVPSPEYIIKEVHTHDTEPPTSDPPKESPIVQLVQEEEEEASPSTVTLLGSGEQEDESSSWFESETQILCSELTSICCISSFSEYLYKWCSVRIALYRQHSRT-VSKGKD--VSPQPSLLPPVDSVEVSVLQPPSGNVDKEDMERELETVALDDLSS-VHQAHVRNHTVDTVELEPSYPQTLSQSLPLDVTPEMDSLSTVEGSESVKSEGGHKPSQVMPQESSVEFDDETEKKPESFSSVAKLSVIYETSKVNEVMDGPVKEDIVSTHVVTKFPETKFPETVAPPPINTAAVPESEGMETKPSLADTLKHVVTPVTDP-SLPEVKEDEQSPDDALLRGLQRTATDFYAELQNSTDLGYGNGNLVHGSNQKESVFMRLNNRIK----------------------ALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQT---------EAIHLLQAQLTNMTQIVSN-----------LSATVAELKREVSDRQSYLVMSLVLCVVLGLMLCMQRCRNTSQ----------FDGDYTSKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLIRSKSLQFTGKE-DPNDLYIVEPLKFSPEKKKKRCKYKTEKIETIKPADPLHPIANGDIKGRKPFTNQRDFSSMGEVYHSSYKGPPSEGSSE-----TSSQSEESYFCGISACTSLCNGQTQKTKLR-RGLKRRRSKVQDQGKLIKALIQTKSGSLPSLHDIIKGNKEITVGAFGVTAVSGHI---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBS9-1", "uniprot_id": "SUCO_HUMAN", "id": "Q9UBS9-1", "name": "SUN domain-containing ossification factor", "aln": "--MKKHRRALALVSCLFLCSLVWLPSWRVCCKESSSASASSYYSQDDNCALENEDVQFQKKDEREGPINAESL------GKSGSNLPISPKEHKLKDDSIVDVQNTES-KKLSPPVVETLPTVDLHEESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTI----------PIAKPSETEQSETDCDVGEALDASAPIEQPSFVS--------------------------------PPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGD-----------------------PKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHATKKVQKN-------------RNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCST-KIWFVIELCEPIQVKQLDIANYELFSSTPKDFLVSISDRYPTNK--WIKLGTFHGRDERNVQSFPLDEQMYAKYVKMFIKYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYHSERQELFDEDYDYPLDYNTGEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATAAPKMPESTPVSTPVPSPEYVTTEVHTHDMEPSTPDTPKESPIVQLVQEEEEEASPSTVTLLGSGEQEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVALYRQRSRTALSKGKDYLVLAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVELEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQKSESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSET------IVPPINTATVPDNEDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYANGNLVHGSNQKESVFMRLNNRIK----------------------ALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQT---------EAIQLLQAQLTNMTQLVSN-----------LSATVAELKREVSDRQSYLVISLVLCVVLGLMLCMQRCRNTSQ----------FDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLMRSKSLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKIEKIETIKPEEPLHPIANGDIKGRKPFTNQRDFSNMGEVYHSSYKGPPSEGSSE-----TSSQSEESYFCGISACTSLCNGQSQKTKTEKRALKRRRSKVQDQGKLIKTLIQTKSGSLPSLHDIIKGNKEITVGTFGVTAVSGHI---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12232-1", "uniprot_id": "SLP1_YEAST", "id": "Q12232-1", "name": "Uncharacterized protein SLP1", "aln": "-----------MANRLLIYGLILWVSIIGS------------FALDRNKTAQNAKIGLHDTTVITTGSTTNVQ------KEHSSPLSTG-----------------------------SLRTHDFRQASKVDIRQADIRENG-----------------ERKEQD----------ALTQPATPRNPGDSSNSFLSFDEWKKVKSKEHSS--------------------------------GPE----RHLSRVR-----EPVDPSCYKEKECIGEELEID-----------------------LGFLTNKNEWSEREEN-----------------------------QKGFNEEKD---------------IEKVYKK-------------KFNYASLDCAATIVKSNPEAIGATSTLIESKDKYLLNPCSAPQQFIVIELCEDILVEEIEIANYEFFSSTFKRFRVSVSDRIPMVKNEWTILGEFEARNSRELQKFQIHN------PQIWASYLKIEILSHYEDEFYCPISLIKVYGKSMMDEFK----------------------------------------------------------------------------------------------------------------------IDQLKAQEDKEQSIGTNNINNLNEQNIQDR---------------------------------------------------------------CNNIETRLETP--------------NTSNLSDLAG-----------------------------------------------ALSCTSKLIP---------LKFDEFFKVLNASFCPSKQMISSSSSSAVPVIPE-----------------------------------------------------------------------------------------------------------------ESIFKNIMKRLS----------------------QLETNSSLTVSYIEEQSKLLSKSFEQLEMAH-----------------EAKFS---------HLVTIFNETMMSNLDLLNN-----------FANQLKDQSLRILEEQ---------------------KLENDK----------FTNRHLLHLERLEKEVSFQRRIVYASFFAFVGLISYLLITR------------------------------------------------------------------------ELYFEDFEESK-------------------------------NGAIEKADIVQQAIR------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VIK7-1", "uniprot_id": "Q9VIK7_DROME", "id": "Q9VIK7-1", "name": "SUN domain-containing protein", "aln": "MHMRLHLVRFMFINLLLSCCFWLYDNVAAADSQIPSRAGDSAKDAARKTHIEPEEPAAPPRPEPPPPPLHNGAGVLLPSAQEGVPIVATSSSSSFAEVPQTGNRPISGDTSVPVKELPALSDQQRTKSHSEYISEIDLAADVGGASSSTAQVPNNQLNYNKRSSAGKVHRFSESQQLDQPKQLEQEEPATGQPKAPELQEPPQLPQAEESFPEIITELPAVTITELPLDRVMNRLDSVILDGSPATAGNHSDEEQHQQQQQPHEDQPMQVSEADEEVPQKDEQMPKINDPGGGIQVEGMVTPEAATVGETQESSEELQPGSAAFNGTEGTANLTNANEEVPMPVFSEWAQKQMEAEASREQAMELEQQVVNKSAQRKNNTGSSSGKPPTLKLRSKNYASPDCGAKIIAHNSESKHTEAVLTQSTDEYMLSTCES-RIWFVVELCEAIQAQKVDVANYELFSSSPKNFTVAVSKRFPTRD--WSNVGRFAAEDKRTIQTFELHP-------HLFGKFVRVDITSHYANEHFCPLSLFRVFGTSEYEAFETEIRPS-----DDLDDFYDDYGAQEQKAAVGSGGNIFQSASDAVMQMVKKAAEVLVKPTKALKWSEESVLCQTPAFEAFSCINCN--TTLVERINSLLSCQFQQLQALLSLSHLRSDLLNSRVCQEEFGISLTGSEFASKMGKEQSYFLSMLPAEHVGAMCKLIQAEQNVTDHNHTKAPSLKQHVSSPEPVQDNATATG--------VRQDCENSKTPTKEPLTPSLEVVVPEVSQEVPSMEDQSSTSSETVSTTNSTPADVNIFNMPSEPEEVVVKVQLPPEPTLPTTLQPSDVESFTDAPSTNALPGSSEAVANGDLGMEEGNPANWDGIDNLLTTTVASITAGGGAAAAAAAVVNGNANIGG----AGIVGAGGPASLSSVNMQQKLTNGAQSESVFIRLSNRIKALERNMSLSGQYLEELSRRYKKQVEELQQTLTQQTLTVRQLEDQSRRYVEQEQLYQQHSAELAGEVRALSYQVQACILVIIIVGTCIFLMLVLGTVYYRKLRRQQQQLLKKDQAGHPPVAAKPKLDRRKSYEQTPNQSTPKQRRPSEEAMLILKECGDSNMQELDPPSRQRKISVCYGSNNNIAANMAIANTNGGASVRNSLHRRKGAKHSWHNSLDTTETSCGEQTDKFFDVDTLKSIKQSCGKPGKKKSLQQLKPLGLKRQESAPATYTPDLQAEEPATQSDFDESLMLDDDDLANFIPTSDLAYNEFMPEGPSGYQIVDTVDGKPGKEPGTKKSRRLSSPAFFKSPFSKSKNKGYSFNGVKNSHAVHEPTSWEWYRLKRSEKHQQQQQAKLVSKSLPSASLDSSSLSEVNFPLSSSTATTQNSFRILGEAILSSGEGRITPNGNGNAMSGGLASSSSGSGSGGSTTSSTTKKKQRALNNLFRKAFDF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * : . . : . : : . : :* : : . : : : :. : :* .: . : : : . . .* .. . : . . * * . .. : : . :* :: * . :: :. **** :*.*.*: *.*: : : * :. * *:*..*.: : ::*:**** * .::.::****:***: * * *::*.* * . * :* * ..:.* :*.* :. ::: .:::::: **: .*.:**:**::*:*.* : :: : . :*: * : . :: . :. .. * :. : * :. :. . : . . :. . *.:: . .: : * * .: : : ::: : .. . : . : ::: . : :. : . : : : . : * : : . :: : . : : * .: . :. . : :::. :.: ", "identical_positions": 66, "similar_positions": 198, "identity": "4.56%" }, { "cls_id": "homologset.agr.SGD:S000005682", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70260-1", "uniprot_id": "PIAS3_RAT", "id": "O70260-1", "name": "E3 SUMO-protein ligase PIAS3", "aln": "--------------------------------------MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMK-IKELYRRRFPRKTLGPSDLSLLS--------LPPGTSP-VGSPS--PLA------SIP------PTLLTPGTLLGPKREVDMH--PPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFE-EAHFTFALTPQQLQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILNSC---SDCDEIQFMEDGSWCPMKPKKEASEVCPPPGYGLDG-------------LQYSPVQEGNQSENKKRVEVIDLTI---ESSSDEED-LPPTKKHCPVTSAAIPALPGSKGALTSGHQPSSVLRSPAMGTLGSDFLSSLPLHEYPPAFPLG------ADIQGLDLFSFLQTESQHYSPSVITS---------LDEQDTLG--HFFQFRGTPPHFLGPLAPTLGSSHRSATPAPAPGRVSSIVAPGSSLREGHGGPLPSGP-----SLTGCRSDVISLD-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54714-1", "uniprot_id": "PIAS3_MOUSE", "id": "O54714-1", "name": "E3 SUMO-protein ligase PIAS3", "aln": "--------------------------------------MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMK-IKELYRRRFPRKTLGPSDLSLLS--------LPPGTSP-VGSPG--PLA------PIP------PTLLTPGTLLGPKREVDMH--PPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFE-EAHFTFALTPQQLQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILNSC---SDCDEIQFMEDGSWCPMKPKKEASEVCPPPGYGLDG-------------LQYSAVQEGIQPESKKRVEVIDLTI---ESSSDEED-LPPTKKHCPVTSAAIPALPGSKGALTSGHQPSSVLRSPAMGTLGSDFLSSLPLHEYPPAFPLG------ADIQGLDLFSFLQTESQHYGPSVITS---------LDEQDTLG--HFFQYRGTPSHFLGPLAPTLGSSHRSSTPAPPPGRVSSIVAPGSSLREGHGGPLPSGP-----SLTGCRSDVISLD-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6X2-1", "uniprot_id": "PIAS3_HUMAN", "id": "Q9Y6X2-1", "name": "E3 SUMO-protein ligase PIAS3", "aln": "--------------------------------------MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMK-IKELYRRRFPRKTLGPSDLSLLS--------LPPGTSP-VGSPG--PLA------PIP------PTLLAPGTLLGPKREVDMH--PPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFE-EAHFTFALTPQQVQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILSSC---SDCDEIQFMEDGSWCPMKPKKEASEVCPPPGYGLDG-------------LQYSPVQGGDPSENKKKVEVIDLTI---ESSSDEED-LPPTKKHCSVTSAAIPALPGSKGVLTSGHQPSSVLRSPAMGTLGGDFLSSLPLHEYPPAFPLG------ADIQGLDLFSFLQTESQHYGPSVITS---------LDEQDALG--HFFQYRGTPSHFLGPLAPTLGSSHCSATPAPPPGRVSSIVAPGGALREGHGGPLPSGP-----SLTGCRSDIISLD-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88907-1", "uniprot_id": "PIAS1_MOUSE", "id": "O88907-1", "name": "E3 SUMO-protein ligase PIAS1", "aln": "--------------------------------------MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMK-IKELYRRRFPQKIMTPADLSIPN--------VHSSPMPPTLSPS--TIP------QLTYDGHPASSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFR-ETCFAFALTPQQVQQISSSMDIS-GTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRTYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYC---TDCDEIQFKEDGSWAPMRSKKEVQEVTASYN-GVDGC--------LSSTLEHQVASHNQSSNKNKKVEVIDLTI---DSSSDEEEEEPPAKRTCPSLSPTSPLS--NKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPM---PYDLQGLDFFPFLSGDNQHYNTSLLAAAAA----AVSDDQDLLHSSRFFPYT-SSQMFLDQLS-AGGSTSLPATNGSSSGSNSSLVSS-NSLRESHGHGVASRSSADTASIFGIIPDIISLD-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AIY4-1", "uniprot_id": "A0A8I6AIY4_RAT", "id": "A0A8I6AIY4-1", "name": "", "aln": "--------------------------------------MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMK-IKELYRRRFPQKIMTPADLSIPN--------VHSSPMPATLSPS--TIP------QLTYDGHPASSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFR-ETCFAFALTPQQVQQISSSMDIS-GTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRTYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYC---TDCDEIQFKEDGSWAPMRSKKEVQEVTASYN-GVDGC--------LSSTLEHQVASHNQSSNKNKKVEVIDLTI---DSSSDEEEEEPPAKRTCPSLSPTSPLS--NKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPM---PYDLQGLDFFPFLSGDNQHYNTSLLAAAAA----AVSDDQDLLHSSRFFPYT-SSQMFLDQLS-AGGSTSLPATNGSSSGSNSSLVSS-NSLRESHGHGVASRSSADTASIFGIIPDIISLD-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75925-1", "uniprot_id": "PIAS1_HUMAN", "id": "O75925-1", "name": "E3 SUMO-protein ligase PIAS1", "aln": "--------------------------------------MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMK-IKELYRRRFPQKIMTPADLSIPN--------VHSSPMPATLSPS--TIP------QLTYDGHPASSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFR-ETCFAFALTPQQVQQISSSMDIS-GTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYC---TDCDEIQFKEDGTWAPMRSKKEVQEVSASYN-GVDGC--------LSSTLEHQVASHHQSSNKNKKVEVIDLTI---DSSSDEEEEEPSAKRTCPSLSPTSPLN--NKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPM---PYDLQGLDFFPFLSGDNQHYNTSLLAAAAA----AVSDDQDLLHSSRFFPYT-SSQMFLDQLS-AGGSTSLPTTNGSSSGSNSSLVSS-NSLRESHSHTVTNRSSTDTASIFGIIPDIISLD-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C5D8-1", "uniprot_id": "PIAS2_MOUSE", "id": "Q8C5D8-1", "name": "E3 SUMO-protein ligase PIAS2", "aln": "--------------------------------------MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIK-IRELYRRRYPRTLEGLCDLSTIKSSVFS---LDGSSSP-VEPDL--PVAGIHSLPSTSITPHSPSSPVGSVLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQ-EKFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDC---SDVDEIKFQEDGSWCPMRPKKEAMKVTSQPCTKVES----------SSVFSKPCSVTVASDASKKKIDVIDLTI---ESSSDEEED-PPAKRKCIFMSETQSSP--TKGVLMY--QPS-SVRVPSVTSVDPAAIPPS-LTDYSVPFHHTPVSSMSSDLPGLDFLSLIPVDP----------------------------------QYCPPMFLDSLTSPLTASSTSVTTTSP-HESSTHVSSSSSRSE--TGVITSSG--------RNIPDIISLD-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75928-1", "uniprot_id": "PIAS2_HUMAN", "id": "O75928-1", "name": "E3 SUMO-protein ligase PIAS2", "aln": "--------------------------------------MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIK-IRELYRRRYPRTLEGLSDLSTIKSSVFS---LDGGSSP-VEPDL--AVAGIHSLPSTSVTPHSPSSPVGSVLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQ-EKFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDC---SDVDEIKFQEDGSWCPMRPKKEAMKVSSQPCTKIES----------SSVLSKPCSVTVASEASKKKVDVIDLTI---ESSSDEEED-PPAKRKCIFMSETQSSP--TKGVLMY--QPS-SVRVPSVTSVDPAAIPPS-LTDYSVPFHHTPISSMSSDLPGLDFLSLIPVDP----------------------------------QYCPPMFLDSLTSPLTASSTSVTTTSS-HESSTHVSSSSSRSE--TGVITSSG--------SNIPDIISLD-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6AZ28-1", "uniprot_id": "PIAS2_RAT", "id": "Q6AZ28-1", "name": "E3 SUMO-protein ligase PIAS2", "aln": "--------------------------------------MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCTPAVQIK-IRELYRRRYPRTLEGLSDLSTIKSSVFS---LDGSSSP-VEPDL--AVAGIHSLPSTSIAPHSPSSPVASVLLQDTKPTFEMQQPSPPIPPVHPDVQLKTLPFYDVLDVLIKPTSLVQSSIQRFQ-EKFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDC---SDVDEIKFQEDGSWCPMRPKKEAMKVTSQPCTKVES----------SSVFSKPCSVTVASDASKKKIDVIDLTI---ESSSDEEED-PPAKRKCIFMSETQSSP--TKGVLMY--QPS-SVRVPSVTSVDPAAIPPS-LTDYSVPFHHTPVSSMSSDLPGEQRRNDINNEV----------------------------------QLG-------------TSSDTVQQ----------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2BCP8-1", "uniprot_id": "A0A8M2BCP8_DANRE", "id": "A0A8M2BCP8-1", "name": "", "aln": "--------------------------------------MADIEELRNMVSSFRVSELQVLLGFAGRNKSGRKHELLLRALHLLRSGCSSAVQIK-IKELYRRRYPRTFEGLQDLAALKSSIKSFIHLDSGATA-VSSDL--TLP-----TDHSDVLQQRRESCDSPVFHESKPMMNMQQPTTLMAPVHPDVQMKSLPFYDVLDVLIKPSSLGAHAVQRFHNEKYFIFALTPQQVREVCISRDFLPGGRRDYMVQIQLRFCLAETSCPQEDNYPNGLCIKVNGKLFPLPGFAPPPKNGVEQKRPGRPLNITSLVRLSSAVPNQIVVTWAPEIGKTYSMSVYLVRQLTSPLLLQRLRMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTVPCRAVTCSHLQCFDAALYLQMNEKKPTWICPVCDKKATYESLIIDGLFMEILNDC---TDVDEIQFQEDGTWCPMRPKKETLKLSSPCISKIDC----------SVPVRQSAVVSVPETSSTKKADVIDLTL---ESSSDDEEDDPPLKKRCIYMSKAEEMH--SKGVLTY--QPS-TVRVPNVQSLDTSYLTSS-IADYSVPFHHSSLSTIPTDMQSLDLFSLIQGDPQQ--------------------------------HFRGPIFLDSLSSSLQSATTSASLVSSSAQYETATHSSSSSHE--TGVITGGS--------SGLSDIISLD-----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9JM05-1", "uniprot_id": "PIAS4_MOUSE", "id": "Q9JM05-1", "name": "E3 SUMO-protein ligase PIAS4", "aln": "-------------------------------------MAAELVEAKNMVMSFRVSDLQMLLGFVGRSKSGLKHELVTRALQLVQFDCSPELFKK-IKELYETRYAKKSAEPGPQAPRP--------LDP--LALHS-----------------MPRTPLSGPTVDYPVLYGKYLNGLGR--LPTKTLKPEVRLVKLPFFNMLDELLKPTELVPQSAEKLQ-ESPCIFALTPRQVEMIRNSRELQPGVKA---VQVVLRICYSDTSCPQEDQYPPNIAVKVNHSYCSVPGYYPSNKPGVEPKRPCRPINLTHLMYLSSAT-NRITVTWG-NYGKSYSVALYLVRQLTSSDLLQRLKTIGVKHPELCKALVKEKLRLDPDSEIATTGVRVSLICPLVKMRLSVPCRAETCAHLQCFDAVFYLQMNEKKPTWMCPVCDKPAAYDQLIIDGLLSKILSEC---EGADEIEFLAEGSWRPIRAEKEP--------------------------------------SCSPQGPILVLGT---SDAN--------------GLAPASSTPGIGSGLSGPGSAGSGAGAAGSLE----------------------------NGKTGADVVDLTLDSS-----------------------------------------------SSSEDEDEDEDDDEDEDE--GPRPKR-RCPFQKGLVPAC------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B5DFF9-1", "uniprot_id": "B5DFF9_RAT", "id": "B5DFF9-1", "name": "E3 SUMO-protein ligase PIAS4", "aln": "-------------------------------------MAAELVEAKNMVMSFRVSDLQMLLGFVGRSKSGLKHELVTRALQLVQFDCSPELFKK-IKELYETRYAKKSAEPGPQAPRP--------LDP--LALHS-----------------MPRTPLSGPTVDYPVLYGKYLNGLGR--LPTKALKPEVRLVKLPFFNMLDELLKPTELVPQSAEKLQ-ESPCIFALTPRQVEMIRNSRELQPGVKA---VQVVLRICYSDTSCPQEDQYPPNIAVKVNHSYCSVPGYYPSNKPGVEPKRPCRPINLTHLMYLSSAT-NRITVTWG-NYGKSYSVALYLVRQLTSSDLLQRLKTIGVKHPELCKALVKEKLRLDPDSEIATTGVRVSLICPLVKMRLSVPCRAETCAHLQCFDAVFYLQMNEKKPTWMCPVCDKPAAYDQLIIDGLLSKILSEC---EDADEIEFLAEGSWRPIRAEKEP--------------------------------------SCSPQGPILVLGT---SDAN--------------GLAPASSTPGMGSGLSGPGGAGGGAGAAGGLE----------------------------NGKTGADVVDLTLDSS-----------------------------------------------SSSEDEDEDEDDDEDDDE--GPRPKR-RCPFQKGLVPAC------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N2W9-1", "uniprot_id": "PIAS4_HUMAN", "id": "Q8N2W9-1", "name": "E3 SUMO-protein ligase PIAS4", "aln": "-------------------------------------MAAELVEAKNMVMSFRVSDLQMLLGFVGRSKSGLKHELVTRALQLVQFDCSPELFKK-IKELYETRYAKKNSEPAPQPHRP--------LDP--LTMHSTYDRAG----------AVPRTPLAGPNIDYPVLYGKYLNGLGR--LPAKTLKPEVRLVKLPFFNMLDELLKPTELVPQNNEKLQ-ESPCIFALTPRQVELIRNSRELQPGVKA---VQVVLRICYSDTSCPQEDQYPPNIAVKVNHSYCSVPGYYPSNKPGVEPKRPCRPINLTHLMYLSSAT-NRITVTWG-NYGKSYSVALYLVRQLTSSELLQRLKTIGVKHPELCKALVKEKLRLDPDSEIATTGVRVSLICPLVKMRLSVPCRAETCAHLQCFDAVFYLQMNEKKPTWMCPVCDKPAPYDQLIIDGLLSKILSEC---EDADEIEYLVDGSWCPIRAEKER--------------------------------------SCSPQGAILVLGP---SDAN--------------GLLPAPSVN--GSGALG---STGGGGPVGSME----------------------------NGKPGADVVDLTLDSS-----------------------------------------------SSSEDEEEEEEEEEDEDEE-GPRPKR-RCPFQKGLVPAC------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R4C4-1", "uniprot_id": "PIS4A_DANRE", "id": "F1R4C4-1", "name": "E3 SUMO-protein ligase PIAS4-A", "aln": "-------------------------------------MAAELVEAMNMVKSFRVSDLQTLLASMGRSKSGLKQDLVGRALRLVQTEYSPELLKN-VRQLYETRFPKASAWLAARRPET--------VAVNYPALNS-----------------SPRGTGQG---------TDYLNGIP---KPAPPPAAEVKLVPLPFYHNLETLLPPTELVAQNSEKLQ-ESQCVFDLTPNQVDQIRNSSELRPGMKS---VQVVLRICYTDSIGVQEDQYPPNIAVKVNQSYCHVPGYYPSNKPGVEPRRPCRPVNITPWLHLSTVT-NRVTITWG-NFGKRYSVAVYLVRVFTSGELFNQLKHCSVENPDRCRERIQDKLRFDPESEIATTGLRVSLICPLVKMRLGVPCRVLTCAHLQCFDAVFFLQMNEKKPTWTCPVCDKPAPFELLTIDGLLSEILKETP--EDVEEIEYLTDGSWRPIRDDKEKERE--------------------------------RENSRTPDYPVVDICV---PEAN--------------GHSPAHSGTN-QTGKSG---SGGASAGTGSTS----------------------------GGSGGGTVVDLTLDDS-----------------------------------------------SEEEGGGGAEDSEETDDSQDSPAPKRGRYDYDKDLVTAY------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7P5-1", "uniprot_id": "A1Z7P5_DROME", "id": "A1Z7P5-1", "name": "", "aln": "MRKTRSQTARTQAENAATSSSPGHQSTSSAPIAVNPFDSTKYKECEQMVQMLRVVELQKILSFLNISFAGRKTDLQSRILSFLRTN-LELLAPK-VQEVYAQSVQEQNATLQYIDPTR------MYSHIQLPPTVQPNP----------VGLVGSGQGVQVPGGQMNVVGGAPFLHTHS-INSQLPIHPDVRLKKLAFYDVLGTLIKPSTLVPRNTQRVQ-EVPFYFTLTPQQATEIASNRDIRNSSKVEHAIQVQLRFCLVETSCDQEDCFPPNVNVKVNNKLCQLPNVIPTNRPNVEPKRPPRPVNVTSNVKLSPTVTNTITVQWCPDYTRSYCLAVYLVKKLTSTQLLQRMKTKGVKPADYTRGLIKEKLTEDADCEIATTMLKVSLNCPLGKMKMLLPCRASTCSHLQCFDASLYLQMNERKPTWNCPVCDKPAIYDNLVIDGYFQEVLGSSLLKSDDTEIQLHQDGSWSTPGLRSETQILDTP-------------------------------SKPAQKVEVISDDI---ELISDDAKPVKRDLSPAQDEQPTSTSNSETVDLTLSDSDDDMPLAKRRPPAKQAVASSTSNGSGGGQRAYTPAQQPQQSESPEQQASRQSPEKQ----------------------------------------TVSEQQLQQQQHEQPATAAVHASLLESLAAAVADQKHFQLLDLAAVAAAAAATASSGQSQNAGP------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12216-1", "uniprot_id": "SIZ2_YEAST", "id": "Q12216-1", "name": "E3 SUMO-protein ligase SIZ2", "aln": "-------------------------------MASVMSNNNNNNNNNNASYMFTNPLSNTGGGLINEIKDAINEMEQLKVLELKQICKSLDLSITGKKAVLQDRIKQFLRKSCDIGHIDP-------WRPKAIKILIAKVR---------INSSLPKYSTLWETLKTGAFKHPVASGQLPVTALQSTALPPYSQQQALAYSFTSPFYKPIVQIPDANKKLKQSAGRGCTKMKFKVSKSNHDLLKSNKSYKLYLFSGFSIPFIYETVGHEAIDFPYPCELVFNGTKLEDN-----VKGLKKQNGTGNPANLTPYLKVPTEMNHLDLHYLN--IDKEYSISCFIVEVFSPEALLGKILKRPKIIKQATTAYIKRTLNEQDDDDIITTSTVLSLQCPISCTRMKYPAKTDQCKHIQCFDALWFLHSQSQVPTWQCPICQHPIKFDQLKISEFVDNIIQNCN--EDVEQVEISVDGSWKPIHNSSAVITDTVNQNHSVKNENQGTVKQEQDYDSRNAFDTNLRNGSNHNEPEIISLDSSDDEAFIPASKSFPTHVNPRNDQLRADIFPSESEGSSDYNPNHTSTPKGSPTMDQDNYQDAFQMRSFLNQGATTNINDTPTNNSSINSFVTATNGDSRIFYNRGPSTPLLPAVLQNLTNQTEAQRNPYGPNYNTTAQDRNLLGIEGDLPPIPPVDPNSEAETELPTRTTSAAHLPPYIHVSTSGHGDDGKIRKRRHSNVSIYIPKNPYATLMKRRPQANHAIMNKTLAQTNDFNTSAQDNSEVVDLTSD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : : . . . : : * : : : . : : . . . : : * ::.. . : . .. :: : :* : .* . : : . . .* *:* :.. : : *.:: ::*. ::. *: :: : :: .* : : :: ** :** **: :: *.:. * *:*.*** ::: :.: *** **:*:: :: * :. . ::: . ::: :*:* . . :: : . . ", "identical_positions": 33, "similar_positions": 107, "identity": "4.22%" }, { "cls_id": "homologset.agr.SGD:S000005683", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70195-1", "uniprot_id": "PSB7_MOUSE", "id": "P70195-1", "name": "Proteasome subunit beta type-7", "aln": "---------MAAVSVFQPPVGGFSFDNCRRNAVLEADFAKKGFKLPKARKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLTTGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDLGSGSNIDLCVISK-SKLDFLRPFSVPNKKGTRLGRYRCEKGTTAVLTEKVTPLEIEVLEETVQTMDTS---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JHW0-1", "uniprot_id": "PSB7_RAT", "id": "Q9JHW0-1", "name": "Proteasome subunit beta type-7", "aln": "---------MAAVSVFQAPVGGFSFDNCRRNAVLEADFAKKGFKLPKARKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLTTGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDLGSGSNIDLCVISK-SKLDFLRPYSVPNKKGTRFGRYRCEKGTTAVLTEKVTPLELEVLEEIVQTMDTS---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99436-1", "uniprot_id": "PSB7_HUMAN", "id": "Q99436-1", "name": "Proteasome subunit beta type-7", "aln": "---------MAAVSVYAPPVGGFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISK-NKLDFLRPYTVPNKKGTRLGRYRCEKGTTAVLTEKITPLEIEVLEETVQTMDTS---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35955-1", "uniprot_id": "PSB10_MOUSE", "id": "O35955-1", "name": "Proteasome subunit beta type-10", "aln": "----------MLKQAVE-PTGGFSFENCQRNASLEHVLP--GLRVPHARKTGTTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTTRMAASKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASLVVGGVDLNGPQLYEVHPHGSYSRLPFTALGSGQGAAVALLEDRFQPNMTLEAAQELLVEAITAGILSDLGSGGNVDACVITA-GGAKLQRALSTPTEPVQRAGRYRFAPGTTPVLTREVRPLTLELLEETVQAMEVE---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KM35-1", "uniprot_id": "PSB10_RAT", "id": "Q4KM35-1", "name": "Proteasome subunit beta type-10", "aln": "----------MLKQAVE-HRGGFSFENCQRNASLEHVLP--GLRVPLARKTGTTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTTRMAASKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASLIVGGVDLNGPQLYSVHPHGSYSRLPFTALGSGQDAAVALLEDRFQPNMTLEAAQELLVEAITAGILGDLGSGGSVDACVITA-GGAKLQRALSSPIEPVQRAGQYRFAPGTTPVQTQEVRALTLELLEETVQAMEVE---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40306-1", "uniprot_id": "PSB10_HUMAN", "id": "P40306-1", "name": "Proteasome subunit beta type-10", "aln": "----------MLKPALE-PRGGFSFENCQRNASLERVLP--GLKVPHARKTGTTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVASKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASLIVGGVDLTGPQLYGVHPHGSYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGGNVDACVITK-TGAKLLRTLSSPTEPVKRSGRYHFVPGTTAVLTQTVKPLTLELVEETVQAMEVE---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QR78-1", "uniprot_id": "F1QR78_DANRE", "id": "F1QR78-1", "name": "Proteasome subunit beta", "aln": "----------MLNTSTKTLTGGFSFENTRRNAVLEANLSEKGYSAPNARKTGTTIAGLVFKDGVILGADTRATDDMVVADKNCMKIHYIAPNIYCCGAGVAADAEVTTQMMSSNVELHSLSTGRPPLVAMVTRQLKQMLFRYQGHIGSSLIVGGVDVNGAQLYSVYPHGSYDKLPFLTMGSGAASAISVFEDRYKPNMELEEAKQLVRDAITAGIFCDLGSGSNVDLCVITD-KKVDYLRTYDQPVHKNQRGGTYRYKPGTTAVLSKTVTPLTLDVVDESVHVMDTE---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1LWY1-1", "uniprot_id": "Q1LWY1_DANRE", "id": "Q1LWY1-1", "name": "Proteasome subunit beta", "aln": "--------MALTSHVLEPSLCGFNFENATRNIVLENGAEEGKIKPPKALKTGTTIAGVVFKDGVVLGADTRATSDEVVADKMCAKIHYIAPNIYCCGAGTAADTEKTTDMLSSNLTIFSMNSGRNPRVVMAVNIIQDMLFRYHGMIGANLILGGVDCTGSHLYTVGPYGSMDKVPYLAMGSGDLAAMGILEDRFKVNMDLEQAKALVSDAIQAGIMCDLGSGNNIDLCVITK-EGVDYIRPHKESPYNYKRQAKYKYKSGTTPILTKTVNKLELDLVQETVQMMETSASS------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUJ1-1", "uniprot_id": "Q9VUJ1_DROME", "id": "Q9VUJ1-1", "name": "Proteasome subunit beta", "aln": "-------MDLDNARDLP--RAGFNFDNCKRNATLL----NRGFKPPTTTKTGTTIVGIIYKDGVILGADTRATEGPIVSDKNCAKIHYLAKNIYCCGAGTAADTEMTTDLISSQLELHRLQTDREVRVVAANTMLKQMLFRYQGHISAALVLGGVDKTGPHIYSIHPHGSSDKLPYATMGSGSLAAMTVFESRWKPDLSEEEGKKLVRDAIASGVFNDLGSGSNIDLCVIRK-GSVEYLRNYELANKKGKRQLDYRFKTGTSTVLHTNI--KDLLVT-ERVQAVPMEIS-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W470-1", "uniprot_id": "Q9W470_DROME", "id": "Q9W470-1", "name": "Proteasome subunit beta", "aln": "MLFPFSARKANTSADFVGLRSGFNFINCRRNAELL----SKGYEPPKAIKTGTSIVGIIYKDGVILGADTRATEGPIVSDKNCSKIHHLQDHIYCCGAGTAADTEMITLTTSAELDLHRLNTERRVPVVCASMMLRRTLFRYQGHIGAALVMGGVDTTGPQLYCIYPCGSNDKIPYAAMGSGTLAAMSVLEHGWKPDLDLEQGKQLVREAISAGVFNDLGSGSNIDLCVITA-KGAVYLRTDTIASEKGERLGKYGIKPNSTMVTSISV--LSLQVTDERIYAVDDQQPGTSGVQLDSQQADEELPEGSQTKSP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25043-1", "uniprot_id": "PSB2_YEAST", "id": "P25043-1", "name": "Proteasome subunit beta type-2", "aln": "-------------------MAGLSFDNYQRNNFLAEN----SHTQPKATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIV-NICDIQEEQVDITA-----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:.* * ** * * . .***:*.*: :.:*:::.****:*.. :*:** * *:* : :*:*.***.***:: * .::: :. : : * *. . :: **:*:* :.: *::.*** .*.::: : . ** . : ::*** :*: ::* :: :: * . * :*: :*: *****..:* **: * . : * .:: : : : * : ", "identical_positions": 66, "similar_positions": 84, "identity": "21.02%" }, { "cls_id": "homologset.agr.SGD:S000005685", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62305-1", "uniprot_id": "RUXE_MOUSE", "id": "P62305-1", "name": "Small nuclear ribonucleoprotein E", "aln": "MAYRGQGQKVQKVMVQPINLIFRYLQNRSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLDDAEEIHSKTKSRKQ-------LGRIMLKGDNITLLQSVSN---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62304-1", "uniprot_id": "RUXE_HUMAN", "id": "P62304-1", "name": "Small nuclear ribonucleoprotein E", "aln": "MAYRGQGQKVQKVMVQPINLIFRYLQNRSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLDDAEEIHSKTKSRKQ-------LGRIMLKGDNITLLQSVSN---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZSP1-1", "uniprot_id": "D3ZSP1_RAT", "id": "D3ZSP1-1", "name": "Small nuclear ribonucleoprotein E", "aln": "MAYLGQGQKVQKVMVQPINLIFRYLQNRSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLDDAEEIHSKTKSRKQ-------LGRIMLKGDNITLLQSVSN---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7ZUG0-1", "uniprot_id": "RUXE_DANRE", "id": "Q7ZUG0-1", "name": "Small nuclear ribonucleoprotein E", "aln": "MAYRGQGQKVQKVMVQPINLIFRYLQNRSRISVWLYEQVNMRIEGCIIGFDEYMNLVLDDAEEVHMKTKNRKP-------LGRIMLKGDNITLLQSVSN---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLV5-1", "uniprot_id": "RUXE_DROME", "id": "Q9VLV5-1", "name": "Probable small nuclear ribonucleoprotein E", "aln": "MSFKGN-PKVQKVMVQPINLIFRYLQNRSRVQVWLYENISLRIEGHIVGFDEYMNLVLDDAEEVYVKTRQRRN-------LGRIMLKGDNITLIQNVSPTKD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12330-1", "uniprot_id": "RUXE_YEAST", "id": "Q12330-1", "name": "Small nuclear ribonucleoprotein E", "aln": "MSNKVK----TKAMVPPINCIFNFLQQQTPVTIWLFEQIGIRIKGKIVGFDEFMNVVIDEAVEIPVNSADGKEDVEKGTPLGKILLKGDNITLITSAD----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : *.** *** **.:**::: : :**:*::.:**:* *:****:**:*:*:* *: :: . : **:*:********: ... ", "identical_positions": 39, "similar_positions": 32, "identity": "38.24%" }, { "cls_id": "homologset.agr.SGD:S000005686", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAM0-1", "uniprot_id": "D4AAM0_RAT", "id": "D4AAM0-1", "name": "Transportin-3", "aln": "MEGAKPTLQLVYQAVQALYHDPDPSGKERASFWLGELQRSVHAWEISDQLLQIR----QDVESCYFAAQTMKMKIQTSFYELPTDSHASLRDSLLTHIQNLKDLSP--VIVTQLALAIADLALQMPSWKGCVQTLVEKYSNDVTSLPFLLEILTVLPEEVHSRSLRIGANRRTEIIEDLAFYSSTVVSLLMTCVEKAGTD------EKMLMKVFRCLGSWFNLGVLDSNFMANNKLLALLFEVLQQDKTSSNLHEAASDCVCSALYAIEN-----VETNLPLAMQLFQGVLTLETAYHMAVARE-------DLDKVLNYCRIFTELCETFLEKIVCTPGQGLGDLRTLELLLICAGHPQYEVVEISFNFWYRLGEHLYKTNDEVIHSIFKAYIQRLLHALARHCQLEPDHEGVPEE-TDDFGEFRMRVSDLVKDLIFLIGSMECFAQLYSTLK---EGNPPWEVTEAVLFIMAAIAKSVDPENNPTLVEVLEGVVHLPETVHTAVRYTSIELVGEMSEVVDRNPQFLDPVLGYLMKGLCEKP-------LASAAAKAIHNICSVCRDHMAQHFNGLLEIAHSLDSFMLSPEAAVGLLKGTALVLARLPLDKITECLSELCSVQVMALKKLLSQE---PSNGISSDPTVFLDRLAVIFRHTNP--IVENGQTHPCQKVIQEIWPVLSETLNKH--RADNRIVERCCRCLRFAVRCVGKGSAALLQPLVTQMVNVYHVHQHSCFLYLGSILVDEYGMEEGCRQG--LLDMLQALCIPTFQLLEQ------QNGLQNHPDTVDDLFRLATRFIQRSPVTLLR-SQVVIPILQWAIAST-TLDHRDANSSVMRFLRDLIHTGVAND-------HEEDFEVRKELIGQVMDQLGQQLVSQLLHTCCFCLPPYTLPDVAEVLWEIMQVDR-PTFCRWLENSLKGLPKETTVGAVTVTHK-QLTDFHKQVTSAEECKQVCWALRDFTRLFR---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P2B1-1", "uniprot_id": "TNPO3_MOUSE", "id": "Q6P2B1-1", "name": "Transportin-3", "aln": "MEGAKPTLQLVYQAVQALYHDPDPSGKERASFWLGELQRSVHAWEISDQLLQIR----QDVESCYFAAQTMKMKIQTSFYELPTDSHASLRDSLLTHIQNLKDLSP--VIVTQLALAIADLALQMPSWKGCVQTLVEKYSNDVTSLPFLLEILTVLPEEVHSRSLRIGANRRTEIIEDLAFYSSTVVSLLMTCVEKAGTD------EKMLMKVFRCLGSWFNLGVLDSNFMANNKLLALLFEVLQQDKTSSNLHEAASDCVCSALYAIEN-----VETNLPLAMQLFQGVLTLETAYHMAVARE-------DLDKVLNYCRIFTELCETFLEKIVCTPGQGLGDLRTLELLLICAGHPQYEVVEISFNFWYRLGEHLYKTNDEVIHSIFKAYIQRLLHALARHCQLEPDHEGVPEE-TDDFGEFRMRVSDLVKDLIFLIGSMECFAQLYSTLK---EGNPPWEVTEAVLFIMAAIAKSVDPENNPTLVEVLEGVVHLPETVHTAVRYTSIELVGEMSEVVDRNPQFLDPVLGYLMKGLCEKP-------LASAAAKAIHNICSVCRDHMAQHFNGLLEIAHSLDSFMLSPEAAVGLLKGTALVLARLPLDKITECLSELCSVQVMALKKLLSQE---PSNGISSDPTVFLDRLAVIFRHTNP--IVENGQTHPCQKVIQEIWPVLSETLNKH--RADNRIVERCCRCLRFAVRCVGKGSAALLQPLVTQMVNVYHVHQHSCFLYLGSILVDEYGMEEGCRQG--LLDMLQALCIPTFQLLEQ------QNGLQNHPDTVDDLFRLATRFIQRSPVTLLR-SQVVIPILQWAIAST-TLDHRDANSSVMRFLRDLIHTGVAND-------HEEDFELRKELIGQVMSQLGQQLVSQLLHTCCFCLPPYTLPDVAEVLWEIMQVDR-PTFCRWLENSLKGLPKETTVGAVTVTHK-QLTDFHKQVTSAEECKQVCWALRDFTRLFR---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5L0-2", "uniprot_id": "TNPO3_HUMAN", "id": "Q9Y5L0-2", "name": "Transportin-3", "aln": "MEGAKPTLQLVYQAVQALYHDPDPSGKERASFWLGELQRSVHAWEISDQLLQIR----QDVESCYFAAQTMKMKIQTSFYELPTDSHASLRDSLLTHIQNLKDLSP--VIVTQLALAIADLALQMPSWKGCVQTLVEKYSNDVTSLPFLLEILTVLPEEVHSRSLRIGANRRTEIIEDLAFYSSTVVSLLMTCVEKAGTD------EKMLMKVFRCLGSWFNLGVLDSNFMANNKLLALLFEVLQQDKTSSNLHEAASDCVCSALYAIEN-----VETNLPLAMQLFQGVLTLETAYHMAVARE-------DLDKVLNYCRIFTELCETFLEKIVCTPGQGLGDLRTLELLLICAGHPQYEVVEISFNFWYRLGEHLYKTNDEVIHGIFKAYIQRLLHALARHCQLEPDHEGVPEE-TDDFGEFRMRVSDLVKDLIFLIGSMECFAQLYSTLK---EGNPPWEVTEAVLFIMAAIAKSVDPENNPTLVEVLEGVVRLPETVHTAVRYTSIELVGEMSEVVDRNPQFLDPVLGYLMKGLCEKP-------LASAAAKAIHNICSVCRDHMAQHFNGLLEIARSLDSFLLSPEAAVGLLKGTALVLARLPLDKITECLSELCSVQVMALKKLLSQE---PSNGISSDPTVFLDRLAVIFRHTNP--IVENGQTHPCQKVIQEIWPVLSETLNKH--RADNRIVERCCRCLRFAVRCVGKGSAALLQPLVTQMVNVYHVHQHSCFLYLGSILVDEYGMEEGCRQG--LLDMLQALCIPTFQLLEQ------QNGLQNHPDTVDDLFRLATRFIQRSPVTLLR-SQVVIPILQWAIAST-TLDHRDANCSVMRFLRDLIHTGVAND-------HEEDFELRKELIGQVMNQLGQQLVSQLLHTCCFCLPPYTLPDVAEVLWEIMQVDR-PTFCRWLENSLKGLPKETTVGAVTVTHK-QLTDFHKQVTSAEECKQVCWALRDFTRLFR---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQG0-1", "uniprot_id": "Q9VQG0_DROME", "id": "Q9VQG0-1", "name": "Transportin-3", "aln": "MD--TYSVDVVYQAISALFQGNNPKEQEKANKWLQDFQKSIYSWTIADELLHQK----RDLHANYFAAQTMRNKIQNSFSELPPHTHESLRDSLITHIGQIDEQTDN-VIVTQLSLAVADLALLMASWREPINDLLVTLAPHQCAIWPLLEVLKVLPEEIDSRYLRLGANRREEVHKQLDASAECVLKFLCMCLQREDLDQ-----QRVWNAALRTYSAWLVIHAFPVSHVYNNALTQLAFRLLSLPETSGKLHDNATECVCALLSCINTRQDGASDPESSFEAQLFGAVCMLETPYHLSVAHE-------DTDKTINYCRIFTSLCDAFFYDLLADAQKPHYSLKGLDLVLLCVGHFDYEVAEITFHLWYKLSEDLFQRNEDKLTVLFRPHIERLISALFRHSQMESDHDGLIEE-NNNFFDFRRKVSDLIKDVAFIVGSGACFKQMFHILQ---APETTWESTEAALFIMQNVAKNILPDENEVIPKVVEAILNMSEQTHIAVRYTAILLIGELCDWIENHPESLEAVLNFLLYALQQKNG------LAPAAAIALTSICSACRQKMVCHISGLVEIARSLDSFQINNDVAIGLLKGISLILTRLPREQLQPALREIVGFQLQPLAQLVDSTGSTPQKGERTDPVYWIDRACAIIRHTNP--DVPDNVEHPTVAILNDAWQLISRVMDKY--QSDLRIMERTCRLIRYGIRMVRKQAMMLVEPLIKQMVVLYSVQHHSCFLYVGSILVDEFAKSSECIGG--LLEMLQAFIEPTFGLLQM------ENGLKNNPDTVDDFFRLASRYLDCCPHQLLQ-SSLITPIFQCALIAC-SLDHREANSSVMKFFINLLVWGRSNN-------HSRNTECR-PLVVELASQHGGALVMNLIQASVFQLHSYMLVDVAEVLHELKQVVGNERMQPFLAQALEALPKKNSGGYVTATQQ-QLDEFSSTVLRADTTKAISQALKTFTRLFR---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1ZAR6-1", "uniprot_id": "A1ZAR6_DROME", "id": "A1ZAR6-1", "name": "Exportin-1/Importin-beta-like domain-containing protein", "aln": "-MNAEFTKELVIDAVNMLSSGN----ISLANEYLAAFQKSNDTWIIAEEILSYRP--PHDMHILTFAAMSLAKKIKTSFYSLQKFQLMSLKNSLIDHLKYAAMMRDSNSLIVQLAVGISALGLMFSQWDYELQDFVRKLSENPQYVMALLEVLKVIPEETRPSNLPVEAKKLNSVIDTLEQQSPYILDVLEGLLQRPDLP------DDALPKCLAVCASWTKFSMLSPDQVLQRKLFIMAEFILATPLVNGHLEAAELFVALLEQSLIRK----------ELNSCLANSVICLKPAFKRSMG---------ERSLLQNYCNIFVNLFQTHFRLTQTNPERLNERLVTIELLLLVAEESPLEVIEASLGMWSSISEEVYLHDDPEMYSVYQPYFVRLLDLLLPRAALPANYEFMMPPGSADMQRFRELIGEVLLDMAHMID-DDTVEKLCSIVV---DEQSPWMEVEASVFFLRHLIGNFKEHQTDIISCILKTFFQK-DCQQPFIRLQVLELISIPEIVS------VETIWDCLVNELRRADP------MLSAIDCRLN--------LLMPHWNYLVTLAIMVDEFCLKESERCELLCSICTLIRELPAACVQEAKTSILNIRWIKCPAHIEEN-----------------RHRVLMNSF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99189-1", "uniprot_id": "MTR10_YEAST", "id": "Q99189-1", "name": "mRNA transport regulator MTR10", "aln": "--MDNLQVSDIETALQCISSTASQDDKNKALQFLEQFQRSTVAWSICNEILSKEDPTNALLELNIFAAQTLRNKVTYDLSQLENN-LPQFKDSLLTLLLSHN----QKLIITQLNVALARLAIQFLEWQNPIFEIISLLNSSPSILLNFLRILPEETLDIASTSLTEVEFN-SRIHELIDPIAEDVLKFLVSCIDLLQNTDGNSSSSISLEQILRCLNSWSYEFPVEQLLTVQPLINLVFETISNGNESDMEAFDSAIDCLCVILRESRD------TTNEQLISALFHQLMLLQEKLLPTLFTDHPLNDEYDDDLLEGMTRLFVEAGEAWSVVISKNPD--FFKPMVLVLLMLTCKNEDLDVVSYTFPFWFNFKQSLVLPRYQESRKAYSDIFVKLINGIITHLQYPSGQFSSKEE-EDKFKDFRYHMGDVLKDCTAVVGTSEALSQPLIRIKSAIENNNSWQIMEAPLFSLRTMAKEISLTENTILPEIIKIICNLPEQAK--IRYASTLVLGRYTEWTAKHPELLEVQLQYIFNGFQLHEGSSDMQSIITASSHALMFFCSDCSKLLVGYIDQLINFFLNVQS-SIDIESQFELCQGLSAVINNQPEAKVSVIFQKLVDDNLRQIEALIPQWK-ANPTLLAPQIADKIDLLYALFEELKPRYNYPQQGSEPLLPRIEFIWKALRTLLVDAGAMTDSIIVERVAKLLRRIFERFHVFCEPILPSVAEFLIQGYLTTGFGSYLWCSGSLIVIFGDDESFPISPSLKDAVWKFALSQCETFILNFNKFDKLQLNDYHEAIIDFFSLISDLIMFYPGAFLNSTELLGPVLNVALECVNKLDNYDAYICILRCLDDIISWGFKTPPISTVSIEIVPDEWRKQVINEVVIAHGNQLILVLFIGLVTTFENTAHSDAISCIVKCLRILTEANNNDATICIDWIYKVVEQLGQVTLNERDNLAKAVVEGLNSKDYRKVREGIRAFVGWYSRKNINSRFE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *:. : . * :* :*:* :* *.:::* . :. *** :: *: .: .* .:::**: : ::.** :.:: *.: : .* : :: : :*.:* . : . * . : . : : ::..* :: . : :* . : : : : . . . : * : *: :: : . . .:*.. :: . : *::: . :* . :: :* : : : : : :*: : : .. .: ** :.::: * ::. . : : : .* ** :* : : .. :. : ::: . . : : :* ::. :: :. : : .* : : : . *: : ::. :. . * . . :: . * : .: . . : . .::. ", "identical_positions": 43, "similar_positions": 177, "identity": "4.33%" }, { "cls_id": "homologset.agr.SGD:S000005687", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6MG71-1", "uniprot_id": "CTL4_RAT", "id": "Q6MG71-1", "name": "Choline transporter-like protein 4", "aln": "MGKKQKENE------AYGNSAKYDPSFRGPIKNRGCTDIICCVLFLVFILGYIVVGLVAWVYGDPRQVLYPRNSTGAYCGVG--DNKDKPYVLYFNILSCAAAINVISI--AENGLQCPTPQVCVSSCPQTPWVVEGFQLSNT-VGDVYKEYRNFCVPAVSP---DMVVMDSLQKGLCPSFLLPST---PALGRCFPLPN----------INFTLPEQLQINN--TTVSKGISGLLDSINARDVSVKIFEDFAQSWYWILVALGVALVLSLLFILLLRLVAAPLVLLLIVGVLAVLAYGIYHCWQQYRELRD---QGVSITQLGFTANLS---AYQNVKETWLAALIILAVLEGVLLLMLIFLRQRIRIAIALLKEASRAVGQMMSTMFYPLVTFVLLVICIGYWAVTALYLATSGQPQYVYWVHNTSTPGCEKVLVNVSCDP-MAPLN---SSCPELKCTFTGYSSSGLAQRSLFNLQIYGILGLFWTVNWVLALGQCVLAGAFASFYWAFHKPRDIPTFPLSSAFIRTLRYHTGSLAFGALILTLVQIARVILEYIDHKLRGSQ---NPVARCIICCFKCCLWCLEKFIKFLNRNAYIMIAIYGKNFCVSAKNAFMLLMRNVVRVVVLDKVTDLLLFFGKLLVVGGVGVLSFFFFSGRIKGLGKDFKNPDLNYYWLPIMTSIMGAYVIASGFFSVFGMCVDTLFLCFLEDLERN--DGSQERPYYMPKALLKILGKKNEVPTGGKNRKK---------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VA1-1", "uniprot_id": "CTL4_MOUSE", "id": "Q91VA1-1", "name": "Choline transporter-like protein 4", "aln": "MGRKQNENE------AHGNSAKYDPSFRGPIKNRGCTDIICCVLFLIFILGYIIVGLVAWVYGDPRQVLYPRNSTGAYCGVG--DNKDKPYVLYFDILSCAAAINIISI--AENGLQCPTPQVCVSSCPLAPWAVEVFQFSKT-VGEVYGERRNFCLPAVSP---DMIVEESLQKGLCPRFLLPST---PALGRCFPLPN----------INFTLPEDLRINN--TTVSNGISGLLDSINARDVSVKIFEDFAQSWYWILVALGVALALSLLFILLLRLVAAPLVLLLIVGVLAVLAYGIYHCWQQYQVFRD---KGASITQLGFTTNFS---AYQSVKETWLAALIVLAVLEGILLLMLIFLRQRIRIAIALLKEASRAVGQMMSTMFYPLVTFVLLVICIGYWAVTALYLATSGQPQYIYWASNTSTPGCENVPVNMTCDP-MAPLN---SSCPNLKCVFKGYSTTGLAQRSLFNLQIYGVLGLFWTVNWVLALGQCVLAGAFASFYWAFHKPRDIPTFPLSSAFIRTLRYHTGSLAFGALILSLVQIARVILEYIDHKLRGSQ---NPVARCIICCFKCCLWCLEKFIKFLNRNAYIMIAIYGKNFCVSAKNAFMLLMRNVLRVVVLDKVTDLLLFFGKLLVVGGVGVLSFFFFSGRIKGLGKDFENPNLNYYWLPIMTSIMGAYVIASGFFSVFGMCVDTLFLCFLEDLERN--DGSQERPYYMPKALLKILGKKNEAPTGGKTRKK---------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7T2B0-1", "uniprot_id": "CTL4_DANRE", "id": "Q7T2B0-1", "name": "Choline transporter-like protein 4", "aln": "MGKKKQEEEQ--NSSEYGAPAQYDPTFNGPIHKRSCTDIICCVLFMLVITGYMVVGILAWLYGDPRHVLYPRNSTGMFCGIG--QNQNKPSVLYFDILKCATATNIMAA--ALQGLQCPTTQVCVSSCPSGFWALSPLAYLPN-AKPADYFQQELCVPSLQLKDTTYTVMEIINKELCPYYYTPTT---SVLDRCLPSLGGSAYNPSNIPANFSLPG-LSINQTLSTIANATSDLTNSFNMKDVGLRIFEDFAKTWQWIVAGLVIAMVVSVLFLLLLRFTAPVLIWILIFGVLAVGAFGIWYCYNDYMSLAS---SNLTFSNVGFTTNVQ---VYLQVRDTWLAFLIILCIVEAVLILALIFLRTRILIAIALIQETSKALGHMMSTLLYPVVTFVLLLVCVSYWGITALYLATSGAPIYKVVALNTTQGDCSNIQANQTCDP-QTFNSSRYSSCPSARCVFINYNTEGLFQRNLFNLQIYNVVAFLWCVNFVIALGHCTLAGAFASYYWAFSKPADIPTFPLTQSFMRALRYHVGSLAFGALILTLVQIVRIILEYLDHKFKAAQ---NPCARFLMCCLKCCFWCLEKFIKFINRNAYIMIAIYGKNFCVSAKNAFFLLMRNIVRVVVLDKVTDLLLFFGKLLVVGGIGVLAFFFFSGRIQLPGNTFQTAALNYYWMPIITVVFGAYLIAHGFFSVYNMGVDTLFLCFLEDLERN--DGSAEKPYFMSKNLMKILNKKNKQPKTG--------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5RJI2-1", "uniprot_id": "CTL5_MOUSE", "id": "Q5RJI2-1", "name": "Choline transporter-like protein 5", "aln": "MARKRK---PPSSQ---GDPRRYDPDFQGPTAKRTCTDVLCCLIFLLFILGYVLLGLLAWAHGDPRKMAYPTDSQGHFCGQKGTPNENKTVLFYFNIFRCTSPS-------MMLRLQCSTTQICVSRCPERFLTYLDMQFLNKEDKNYWEYYRQFCKAKAKPVE---TLRDLLISGDCPLAVYPSR---PFLQRCIPDLSALN-GTWTPGSRMKFEDGSGQTRTMLEFREAANGISDLINARTIGLKLLEDYATSWKWILIGLTVAMALSWTFLILLRFTAGFLFWFFIFGVLGIIGYGIWYCFLEYSSIQQRPQSTFWMYGFGIQRRVN---MFFHLKETWFSMMIILSAIEIIIIIVLIFLRTRIQVAIILLQEGSKAISYLPSALIYPVLTFILLSICISYWAVTAVFLATSGVPIFKVMVP-----AGQCIYEDETCDPEIFPYTNIPKDCPGASCNFAFYGGRSMYHNYILTFQVYNLFAFLWLINFVIALGQCALAGAFASYYWAMKKPDDIPPYPLFTAFGRAVRYHTGSLAFGSLILASVQMFKVIVEYLDRRLKKAQ---NSAAQFLHCCLQCCFWCLEKMVKFLNRNAYIMIALYGKNFCESTRDAFYLLMRNILKVTVTDEVTYFVLLLGKVLVSGIVGVLAFLLFTERLQIIVDGP--TTLNYYWVPFLTLVFGSYMIAHGFFSVYSMCVETIFICFLEDLERN--EGSPSRPYFVTPALMNILLEQGKIKKQ---------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZLE8-1", "uniprot_id": "A0A8I5ZLE8_RAT", "id": "A0A8I5ZLE8-1", "name": "Choline transporter-like protein", "aln": "MSDSES---TEFEDQDLGDPRRYDPDFQGPTTKRSSTDVMCCMIFVLFIMGYILLGLLAWVHGDPRKMAYPTDSQGQFCGQKGTPNENKTVLFYFNIFRCTGTS-------MMLRLQCSTTQICVSRCPERFLTYVDMQILNKEDKNYWEYYRQFCKAQARPVE---TLADLLSSGDCPLAVYPSR---PFLQRCVPDFSAIN-GNLTLGSRMHFEDGGGQKRTVVELREAASGISDVIDARAIGLKVLEDYSTSWKWILIGLTIAMALSWTFLVLLRFTAGFLFWFFIFGVLGIIGYGIWYCFLEYNSIQQKPQSAIWMYGIGIQTRLN---MFFHLKETWFSMMIILSAIEVVIIIVLIFLRTRIQVAIILLKEGSKAIGYLPSALVYPFLTFILLSICISYWAVTAVFLATSGVPIFKVMVP-----EGECIHEDEACDPEIFPNTDIPKACPGASCNFAFYGGRSMYHNYIATFQLYNLFAFLWLINFVIALGQCALAGAFASYYWAMRKPEDIPRYPLFTAFGRAVRYHTGSLAFGSLILAFVQMFKVIVEYLDRRLKKAQ---NSAAQFLHCCLRCCFWCLEKMVKFLNRNAYIMIALYGKNFCESTRDAFYLLMRNILKVKVTDEVTYFVLLLGKVLVSGIVGVLAFLLFTERLHEIVEGP--TSLNYYWVPFLTLVFGSYLIAHGFFSVYSMCVETIFICFCEDLERN--DGSAEKPYFVTPSLHSILTKKRPVPQR---------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NCS7-1", "uniprot_id": "CTL5_HUMAN", "id": "Q8NCS7-1", "name": "Choline transporter-like protein 5", "aln": "MNDTEKPADTPSEEEDFGDPRTYDPDFKGPVANRSCTDVLCCMIFLLCIIGYIVLGLVAWVHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNLLRCTSPS-------VLLNLQCPTTQICVSKCPEKFLTYVEMQLLYTKDKSYWEDYRQFCKTTAKPVK---SLTQLLLDDDCPTAIFPSK---PFLQRCFPDFSTKN-GTLTIGSKMMFQDGNGGTRSVVELGIAANGINKLLDAKSLGLKVFEDYARTWYWILIGLTIAMVLSWIFLILLRFIAGCLFWVFMIGVIGIIGYGIWHCYQQYTNLQERPSSVLTIYDIGIQTNIS---MYFELQQTWFTFMIILCIIEVIVILMLIFLRNRIRVAIILLKEGSKAIGYVPSTLVYPALTFILLSICICYWVVTAVFLATSGVPVYKVIAP-----GGHCIHENQTCDPEIFNTTEIAKACPGALCNFAFYGGKSLYHQYIPTFHVYNLFVFLWLINFVIALGQCALAGAFATYYWAMKKPDDIPRYPLFTAFGRAIRYHTGSLAFGSLIIALIQMFKIVLEYLDHRLKRTQ---NTLSKFLQCCLRCCFWCLENAIKFLNRNAYIMIAIYGRNFCRSAKDAFNLLMRNVLKVAVTDEVTYFVLFLGKLLVAGSIGVLAFLFFTQRLPVIAQGP--ASLNYYWVPLLTVIFGSYLIAHGFFSVYAMCVETIFICFCEDLERN--DGSTEKPYFVTPNLHGILIKKQLVPQKQKE------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BY89-1", "uniprot_id": "CTL2_MOUSE", "id": "Q8BY89-1", "name": "Choline transporter-like protein 2", "aln": "MGKDSQN-----YYGKHGTPQKYDPTFKGPIYNRGCTDVICCVLLFLAIVGYVAVGIIAWTHGDPRKVIYPTDSRGEFCGQKGTKNADKPFLFYFNIVKCANPL-------VLLEFHCPTPQICVKQCPDRYLTLLSARN-----TRDFDYYKQFCVPGFQNNK---GVTEILRDGECPAVITPSK---PLAQRCFPAIHASK-GVLMVGNETTYEDGHGARKNITDLVEGAKKANKILEARQLAMQIFEDYTVSWYWIIIGLVIAMVLSLLFIVLLRFLAGIMVWVMIVMVILVLGYGIFHCYMEYSRLRGEAGSDVSLVDLGFQTDLR---VYLHLRQTWMAFMIILSILEVVIILLLIFLRKRILIAIALIKEASRAVGHVMCSLLYPLVTFFLLCLCIAYWASTSVFLSTSNTAVYKVVD------DTACPLLRKTCNPETFPLRNESLQCPTARCQFAFYGGESTYHRALLGLQIFNAFMFFWLANFVLALGQVTLAGAFASYYWAMRKPDDMPAFPLFSAFGRALRYHTGSLAFGSLILAIVQIIRVMLEYLDQRLKAAQ---NKFAKFLMVCLKCCFWCLEKFIKFLNRNAYIMIAIYGTNFCTSARNAFFLLMRNIIRVAVLDKVTDFLFLLGKLLIVGSVGILAFFFFTHRIRIVQDTA--PPLNYYWVPILTVIIGSYLIAHGFFSVYGMCVDTLFLCFLEDLERN--DGSAERPYFMSSTLKKLLNKTNKKVAES--------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B4F795-1", "uniprot_id": "CTL2_RAT", "id": "B4F795-1", "name": "Choline transporter-like protein 2", "aln": "MGKDSQH-----YYGKHGTPQKYDPTFKGPIYNRGCTDIICCVLLFLAIVGYVAVGIIAWTHGDPRKVIYPTDSRGEFCGQKGTKNADKPFLFYFNIVKCASPL-------VLLEFHCPTPQICVKQCPDRYLTFLSARN-----SRDFDYYKQFCVPGFKNNK---GVAEVLRDGECPAVIIPSK---PLAQRCFPAIHASK-GVLMVGNETTYEDGHGTRKNVTDLVEGAKKANKVLEARQLAMQIFEDYTVSWYWIVIGLVIAMLLSLMFIVLLRFLAGVMVWVMIVMVILVLGYGIFHCYAEYSRLRGEAGSDVSLVDLGFQTDLR---VYLHLRQTWMAFMIILSILEVVIILLLIFLRKRILIAIALIKEASRAVGHVMCSMLYPLVTFFLLCLCIAYWASTSVFLSTSNVAVYKIVD------DTPCPLLGKTCNPETFPL-NESRQCPNGRCQFAFYGGESTYHRALLGLQIFNAFMFFWLANFVLALGQVTLAGAFASYYWAMRKPDDMPAFPLFSAFGRALRYHTGSLAFGSLILAIVQIIRVMLEYLDQRLKAAQ---NKFAKFLMVCLKCCFWCLEKFIKFLNRNAYIMIAIYGTNFCTSARNAFFLLMRNIIRVAVLDKVTDFLFLLGKLLIVGSVGILAFFFFTHRIRIVQDTA--PPLNYYWVPILTVIIGSYLIAHGFFSVYGMCVDTLFLCFLEDLERN--DGSAERPYFMSSTLKKLLNKTNKKVAES--------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7SYC9-1", "uniprot_id": "CTL2_DANRE", "id": "Q7SYC9-1", "name": "Choline transporter-like protein 2", "aln": "MDMEEK--------PKYGEPRKFDPSFKGPIQNRGCTDIVCCIIFIIAILGYLAVGILAWTHGDPRKVIYPTDSMGQFCGQG--KLEKQPFLFYFNMMKCASPM-------VLLEFQCPTPQVCVQTCPNRTMTLITAISK----PQDWEYYKSYCKEDP-GHK---AAAQILKEKLCPAYLVSSN---PFLQRCFPSMGKKG-EVITVGDQEKFSDGVNVLD-AKDLMAGMKNASIVMEGRQVAMKIFEDYTKSWYWILICLLIAVVLSLIFIVLLRFLAGVMVWVMILMVVAVIAYGIAHCSIKYVSLKDTPGSNITLQQLGFQPDFA---VYLHIRQTWLAFIIILAILELIIILLLIFLRNRIRVAVELMKEASRAIGYVMSSLVFPIFTFFLLAIVIAFWGVNAVFLSTSSEPVYKVFN------ETECVHSRETCNPENFTSSSMKSDCPHSQCLFAFYGGETPYHKYLILLQFYNVFLFFWCANFVTALGQMTLAGAFASYYWAFDKSKDMPAFPLCASLGRSLRYHTGSLAFGSLLLAIVQVIRVLLEYIDHKLKGAE---NKFAKFLLCCLKCCFWCLEKFIKFINRNAYIMVAIYGKNFCRSARDAFFLLMRNVVRVVVLDKVTDFILFLGKLLIVGLVGIFAFFFFSGQTDAFKGTA--PSLHYYWVPILTVLVCSYLIAHGFFSVYAMCVDTLFLCFLEDLERN--DGSAERPYLMSENLLNVLKKKNQAN-----------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6X893-1", "uniprot_id": "CTL1_MOUSE", "id": "Q6X893-1", "name": "Choline transporter-like protein 1", "aln": "----------MGCCSSAS-AAQSSKREWKPLEDRSCTDIPWLLLFVLFCIGMGFICGFSVATGAAARLVSGYDSYGNICGQR-NAKLEAIPNSGLDHTHRKYVFFLDPCNLDLINRKIKSIALCVAACPRQELKTLSDVQKFAEINGSALCSYNIKPSEYTLTS----KSSG----FCPKLPVPASAPIPFFHRCAPVNISCY-------------------------AKFAEALITFVSDNSVLHRLISGVMTSKEIILGLCLLSLVLSMILMVIIRYISRVLVWILTVLVILGSLGGTGVLWWLYAKQRRSPKEAVIPEQLQIAEDN---------LRALLIYAISATVFTVILFLIMLVMRKRVALTIALFHVAGKVFIHLPLLVFQPFWTFFALVLFWAYWIMTLLFLGTTGSA----------------------------------------VQNE-QGFVEYKISGPLQYMWWYHVVGLIWISEFILACQQMTVAGAVVTYYFTR-DKRNLPFTPILASVNRLIRYHLGTVAKGSFIITLVKIPRMVLMYIHSQLKGK---ENACARCMLKSCICCLWCLEKCLSYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVAAINTVGDFMLFLGKVLIVCSTGLAGIMLLNYQQ----------DYTVWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTKYN--DGSPGREFYMDKVLMEFVENSRKAMKEAGKGGAADAR--------ELKPMLRKR------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VII6-1", "uniprot_id": "CTL1_RAT", "id": "Q8VII6-1", "name": "Choline transporter-like protein 1", "aln": "----------MGCCSSAS-AAQSSKREWKPLEDRSCTDIPWLLLFVLFCIGMGFICGFSVATGAAARLVSGYDSYGNICGQR-NAKLEAIANSGLDHTHRKYVFFLDPCNLDLINRKIKSMALCVAACPRQELKTLSDVQKFAEINGSALCSYNIKPSEYTLTA----KSSA----FCPKLPVPASAPIPFFHRCAPVNISCY-------------------------AKFAEALITFVSDNSVLHRLISGVMTSKEIILGLCLLSLVLSMILMVIIRYISRVLVWILTILVILGSLGGTGVLWWLYAKQRRSPKETVIPEQLQIAEDN---------LRALLIYAISATVFTVILFLIMLVMRKRVALTIALFHVAGKVFIHLPLLVFQPFWTFFALVLFWAYWIMTLLFLGTTGSA----------------------------------------VQNE-QGFVEYKISGPLQYMWWYHVVGLIWISEFILACQQMTVAGAVVTYYFTR-DKRNLPFTPILASVNRLIRYHLGTVAKGSFIITLVKIPRMILMYIHSQLKGK---ENACARCMLKSCICCLWCLEKCLSYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVAAINTVGDFMLFLGKVLIVCSTGLAGIMLLNYQQ----------DYTVWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTKYN--DGSPGREFYMDKVLMEFVENSRKAMKEAGKGGAADAR--------KLKPMASGASSA---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WWI5-1", "uniprot_id": "CTL1_HUMAN", "id": "Q8WWI5-1", "name": "Choline transporter-like protein 1", "aln": "----------MGCCSSASSAAQSSKREWKPLEDRSCTDIPWLLLFILFCIGMGFICGFSIATGAAARLVSGYDSYGNICGQK-NTKLEAIPNSGMDHTQRKYVFFLDPCNLDLINRKIKSVALCVAACPRQELKTLSDVQKFAEINGSALCSYNLKPSEYTTSP----KSSV----LCPKLPVPASAPIPFFHRCAPVNISCY-------------------------AKFAEALITFVSDNSVLHRLISGVMTSKEIILGLCLLSLVLSMILMVIIRYISRVLVWILTILVILGSLGGTGVLWWLYAKQRRSPKETVTPEQLQIAEDN---------LRALLIYAISATVFTVILFLIMLVMRKRVALTIALFHVAGKVFIHLPLLVFQPFWTFFALVLFWVYWIMTLLFLGTTGSP----------------------------------------VQNE-QGFVEFKISGPLQYMWWYHVVGLIWISEFILACQQMTVAGAVVTYYFTR-DKRNLPFTPILASVNRLIRYHLGTVAKGSFIITLVKIPRMILMYIHSQLKGK---ENACARCVLKSCICCLWCLEKCLNYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVATINTVGDFMLFLGKVLIVCSTGLAGIMLLNYQQ----------DYTVWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTKYN--DGSPGREFYMDKVLMEFVENSRKAMKEAGKGGVADSR--------ELKPMASGASSA---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QGI9-1", "uniprot_id": "A0A8M9QGI9_DANRE", "id": "A0A8M9QGI9-1", "name": "Choline transporter-like protein", "aln": "--MSEVRRSGSGSYRPRSSWIKRTKREWKPLEDRSCTDLPWFLLFTLFLVGMCGICGFTIATGGAARLVFGYDSYGNTCGQR-NEPIEGVRLSGLDHTDRKFVFFLDPCNIDIIQRKIKSMALCVSQCPTEELLTYYDLKRFAMMNGSELCSYELPGHKYPSLP----ERFD----KCPKLPVPESKALPVFNRCTPVDISCY-------------------------AKFAEAVVTFVSDNSMLNRLIAGVAASKEIIVGLCLLALVLSMILMVIIRYISAVLVWILTALVVLGSLGGTSVLWWLYIDYRMTMNETMTKDLTETEEPNGGMKPTKDHAQGLLIYAVSATVFTGILLLLMLFMRKRVALTIALFHVAGKVFIHLPLLALQPFCTFLALSLFWVYWIMVLLFLGTTGNP----------------------------------------EKNEDTGLVEFRLSGALQYMTWYHAVGLIWISEFILACQQMTVAGAVVTYYFTR-DKTKLPVTPILSSVLRLVRYHLGTVAKGSFIITLVKIPRLILMYIHNQLKGK---ENACARCMLKACICCLWCLEKCLNYLNQNAYAATAINSTSFCTSARDAFMILVENALRVATINTVGDFVLFLGKVLIVTCTAFAGVLALNYQR----------DYTEWVLPLIIVCLFAFLVAHCFLSIFEIVVDVLFLCFAIDTKYN--NGTPGREFYMDKALMEFVENSRRSMAMEERGRSKRARPKEEVELTEVKAMVSGDGGSAGAEWQALQEFHLYYLLLCVLMDWALTEHTLVLCLTQDMIIFLSVCLPTSTLFFLVTLLQSPPVAAAAC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q921V7-1", "uniprot_id": "CTL3_MOUSE", "id": "Q921V7-1", "name": "Choline transporter-like protein 3", "aln": "---MPGTMQCLGAEYLVSAEKT-RQREWRPQIYRKCTDTPWLVLFFLFWTGLVFIMGYSVVAGAAGRLLFGYDSFGNVCGKK-NSPVEGAPLSGQDMTLKKHVFFMNACNLEVKDRGLGPTALCVSSCPEKQLDTLEEVQLFANINGSFLCVYSLNSFNYTQSS----SADT----LCPRLPVPPSKPFPLFNRCIPQTPECY-------------------------SLFASVLIN---DADALHRILSGIMAGRDTILGLCVFTFALSLAMLFAFRFISTLLIHIIISLVILGLLFVCGVLWWLYYDYTNDLS-----TELDTEKEN---------MNCMLAFAIISTVVTVLLLALIFTLRKRIKLTVELLHVTNKAISSCPFLLFQPLWTCAILIFFWVLWVAVLLSLGTAGTA----------------------------------------QVME-GGQVEYKPLSGIRYMWWYHLIGLIWTSEFILACQRMTVAGAMVACYFNR-NQNDPPARPILSSLFVLFCYHQGTAVKGSFLLTVTRIPRVIFMCIYSTLKEPQ--RSAWSRGEFRCSHCGLWCLLKYLYHLNQDAYTATAINGTDFCTSAKDAHTIIAKNSSHLTSVNCFGNFVIFLGKVLVVCFSIFGGLMAFNYSR----------ALQVWAIPLLLVAFFACVVAHSFLSVFETALDILFLCFAVDLETN--DGSSEKPYFMDPGFLSVIKRTNNLNNAKSQGQKDALPNEEG---TELQPIVR--------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AY92-1", "uniprot_id": "CTL3_RAT", "id": "Q6AY92-1", "name": "Choline transporter-like protein 3", "aln": "-------------------------------------------------------MGYSVVAGAAGRLLFGYDSFGNVCGKR-NSPVEGAPLSGQDMTLKKHVFFMNACNLEVKDRGRGPMALCVSSCPEKQLDTLEEVQLFANINGSFLCVYSLNSFNYTQSP----SADR----LCPRLPVPPSKPFPLFNRCIPQTPECY-------------------------SLFASVLLN---DADALHRILSGIMAGRDTILGLCAFVFALSLAMLFTFRFISTLLVHIIISLVILGLLFVCGVFWWLYYDYTNDLS-----TELDTEKEN---------MKCMLAFAVITTVVTVVLLALIFTLRKRVKLTVELLRVTNKAISRCPFLLLQPLWTFAILVFFWVLWVAVLLSLGTAGTA----------------------------------------QVME-GGQVEYKPLSGIRYLWWYHLIGLIWTSEFILTCQRMTVAGAMVTCYFNR-NQNDPPARPILSSLSTLFCYHQGTAVKGSLLLTVTRIPRVIFMYIYSTVKER---HSAWPRGEFRCSYCGLWCLTNYPYHLNQDAYAAAAINGTDFCTSAKDAHTIISKNSSHLTSVNCFGNFIIFLGKVLVVCFSVFGGLMAFNYNR----------ALQVWAIPLLLVAFFAYLAAHSFLSVFETVLDTLFLCFAVDLETN--DGSSEKPYFMDPGFLSFVKRTDHFNNARSQGHKNSLPNEEG---TELRPIVR--------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N4M1-1", "uniprot_id": "CTL3_HUMAN", "id": "Q8N4M1-1", "name": "Choline transporter-like protein 3", "aln": "-------MHCLGAEYLVSAEGAPRQREWRPQIYRKCTDTAWLFLFFLFWTGLVFIMGYSVVAGAAGRLLFGYDSFGNMCGKK-NSPVEGAPLSGQDMTLKKHVFFMNSCNLEVKGTQLNRMALCVSNCPEEQLDSLEEVQFFANTSGSFLCVYSLNSFNYTHSP----KADS----LCPRLPVPPSKSFPLFNRCVPQTPECY-------------------------SLFASVLIN---DVDTLHRILSGIMSGRDTILGLCILALALSLAMMFTFRFITTLLVHIFISLVILGLLFVCGVLWWLYYDYTNDLS-----IELDTEREN---------MKCVLGFAIVSTGITAVLLVLIFVLRKRIKLTVELFQITNKAISSAPFLLFQPLWTFAILIFFWVLWVAVLLSLGTAGAA----------------------------------------QVME-GGQVEYKPLSGIRYMWSYHLIGLIWTSEFILACQQMTIAGAVVTCYFNR-SKNDPPDHPILSSLSILFFYHQGTVVKGSFLISVVRIPRIIVMYMQNALKEQQ--HGALSRYLFRCCYCCFWCLDKYLLHLNQNAYTTTAINGTDFCTSAKDAFKILSKNSSHFTSINCFGDFIIFLGKVLVVCFTVFGGLMAFNYNR----------AFQVWAVPLLLVAFFAYLVAHSFLSVFETVLDALFLCFAVDLETN--DGSSEKPYFMDQEFLSFVKRSNKLNNARAQQDKHSLRNEEG---TELQAIVR--------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZE7-1", "uniprot_id": "CTL1L_DROME", "id": "Q9VZE7-1", "name": "Choline transporter-like 1", "aln": "----------MGCAESKDGEGEAQNNRPK---YRSCTDTCWLAIYIIFWLFLIVIAIFSFVYGNPLRIINGYDSFGNTCGVKYNEKFQGFPLSGMNTLDKPELFYFDVKELKK------SLKICVKSCPAKTMTKGSELLEYYSQTGTQLCKYDYNMQQLTTAG----NDAKTFNFLGPCPSFPVHESSPVLHRCVPKGTGEK-------------------------VQNYYDMLN---NWDVAQQFVGDIYSTWHIIAMVCGLALLISIALVTMMHWLSRIVSWIICVLVIVASVALTVALWYAYYNIRNKSGVNTQYSMLEEFVRN---------QQAVLTLAVLATITMIILIVVIYFLKNKLAGLSALFEEAGQCMMNLPGLLIAPLLAFLVLIAFLSFWVAVIICLATASSPGQSPIAP---------FDNSKAHQQPLPANALFVSNSTDVNDLRPNARVEYADAGVLRSMFWIYVVGLIWTVEFIFACQQFALAAAVAFWYFQK-PTS----TPTFYAIGKLVKYHLGTVAKGSFVITIFKIPRLILTYLYAKLKKGEDKGSECAACCLKCCICGFWLLEKFIRFLNHNAYTVVAIESINFCPAAGIAWNAMATNVLQVATINSVGDFILFLGKVVVAALSGLIGIVLLKDKP----------GLNFYMAPVIIIIIFSFFIAHIILSLFEMVVDTLFLCVCEDKTLNGRSGRWAQSNLAKLVGEEPLQPGEEPPIEVVQMMPINKQPFSITRLPQSDPEVAPMSAD---------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12412-1", "uniprot_id": "PNS1_YEAST", "id": "Q12412-1", "name": "Protein PNS1", "aln": "---------------------------------------------MPLNEKYERPPQPPPAYDPNHRPPSSSENSAAANVNDGQTPYHFRQDQYYNLN---------------------------SKTSGAPIGSFDEAFPTENDNKPRWNDWPFTIFFLCTVG-------------------------GFIAIAAITLRAWS-----------------------------QTYSSTGSGIYDGVNTGTLNTNAAILLVFVCIIALVFSVLGLTLCRIFPKQFIYCGMVINLVASLG----TAIMYMSLR------------------------------YWSAGIVFLVFTFMTAWCYWGMRSRIPLSVAVLKVVVDAMKKCPQIFFVSFVGALVASAFGFLFSAVIVATYIKYDP--------------------------------------NSSNGGCDVSGGSCSHSKLIGVLVVVFFCGYYISEVIRNVIHCVISGVFGSWYYMSKSDQGMPRWPAFGALKRAMTYSFGSICFGSLLVALIDLLRQILQMIRHDVTSSGG-GQIAIQILFMVFDWIIGFLKWLAEYFNHYAYSFIALYGKPYLRAAKETWYMLREKGMDALINDNLINIALGLFSMFASYMTALFTFLYLRFTS---------PQYNSNGAYNGALMAFSFVIALQICNIATEAIRSGTATFFVALGNDPEVFHHSYPHRFDEIFRAYPDVLRKLSHQNV-------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : :. . . : . . . : . . .* : : . . : * : : :: :: ::. . . . : : . : . . : : : : .::... *: * :. . * *: *::::: : : :. : . : * .:*: ** *: . : :: : : : : . : : : .:. . .. : : . * : .: : . : ", "identical_positions": 13, "similar_positions": 96, "identity": "1.54%" }, { "cls_id": "homologset.agr.SGD:S000005689", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O95989-1", "uniprot_id": "NUDT3_HUMAN", "id": "O95989-1", "name": "Diphosphoinositol polyphosphate phosphohydrolase 1", "aln": "-------------MMKLKSNQTRTYD-GDGYKKRAACLCFRSESEEEVLLVSSSRHPDRWIVPGGGMEPEE-EPSVAAVREVCEEAGVKGTLGRLVGIFE-NQERKHRTYVYVLIVTEVLEDWEDSVNIG--------RKREWFKIEDAIKVLQYHKPVQASYFETLRQGYSANNGTPVVAT--------TYSVSAQSSMSGIR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q566C7-1", "uniprot_id": "NUDT3_RAT", "id": "Q566C7-1", "name": "Diphosphoinositol polyphosphate phosphohydrolase 1", "aln": "-------------MMKLKSNQTRTYD-GDGYKKRAACLCFRSESEEEVLLVSSSRHPDRWIVPGGGMEPEE-EPSVAAVREVCEEAGVKGTLGRLVGIFE-NQERKHRTYVYVLIVTEVLEDWEDSVNIG--------RKREWFKIEEAVKVLQYHKPVQASYFEALRQGYSANNGTPVLPT--------TYS----SSMSGIR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JI46-1", "uniprot_id": "NUDT3_MOUSE", "id": "Q9JI46-1", "name": "Diphosphoinositol polyphosphate phosphohydrolase 1", "aln": "-------------MMKLKSNQTRTYD-GDGYKKRAACLCFRSESEEEVLLVSSSRHPDRWIVPGGGMEPEE-EPSVAAVREVCEEAGVKGTLGRLVGIFE-NQERKHRTYVYVLIVTEVLEDWEDSVNIG--------RKREWFKIEDAIKVLQCHKPVQASYFETLRQGYPANNGTPVVPT--------TYS----SSVSGIR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PIV5-1", "uniprot_id": "A0A8M1PIV5_DANRE", "id": "A0A8M1PIV5-1", "name": "diphosphoinositol-polyphosphate diphosphatase", "aln": "-------------MIKLKSNQTRTYD-RDGYKKRAACLCFRSEREEEVLLVSSSSHPDRWIVPGGGMEPEE-EPSVAAVREVCEEAGVKGTLGRLVGVFE-NRDRKHRTYVYVLIVTEVLEDWEDSVNIG--------RKREWFKTEDARRVLQCHKPVQASYFEALQQDCMTSNGTSLVA---------TYNIN-QNSLSSIR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6Z122-1", "uniprot_id": "A0A8M6Z122_DANRE", "id": "A0A8M6Z122-1", "name": "diphosphoinositol-polyphosphate diphosphatase", "aln": "-------------MMKLKSNQTRTYD-GDGYKKRAACLCFRNDTEQEVLLVSSSRHPDKWIVPGGGMEPEE-EPNVAAAREVCEEAGVKGTLGRLVGIFE-NRDRKHRTYVYVLIVTEVLEDWEDSVNIGKSSGLGFGRKREWFKIDDAIQVLQCHKPVQASYFTALQEGCLNSNGTPLVATIGGGDLSPTYSIN-QSSVSDMR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZYH3-1", "uniprot_id": "D3ZYH3_RAT", "id": "D3ZYH3-1", "name": "", "aln": "--------------MKCKPNQTRTYD-PEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEE-EPDGAAVREVYEEAGVKGKLGRLLGVFEQNQDRKHRTYVFVLTVTELLEDWEDSVSIG--------RKREWFKIEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSAAPSPPESEP----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C028-1", "uniprot_id": "NUD11_MOUSE", "id": "P0C028-1", "name": "Diphosphoinositol polyphosphate phosphohydrolase 3-beta", "aln": "--------------MKCKPNQTRTYD-PEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEE-EPDGAAVREVYEEAGVKGKLGRLLGVFEQNQDRKHRTYVFVLTVTELLEDWEDSVSIG--------RKREWFKIEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSAAPSPPESEP----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C027-1", "uniprot_id": "NUD10_MOUSE", "id": "P0C027-1", "name": "Diphosphoinositol polyphosphate phosphohydrolase 3-alpha", "aln": "--------------MKCKPNQTRTYD-PEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEE-EPDGAAVREVYEEAGVKGKLGRLLGVFEQNQDRKHRTYVFVLTVTELLEDWEDSVSIG--------RKREWFKIEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSAAPSPPESEP----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFP7-1", "uniprot_id": "NUD10_HUMAN", "id": "Q8NFP7-1", "name": "Diphosphoinositol polyphosphate phosphohydrolase 3-alpha", "aln": "--------------MKCKPNQTRTYD-PEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEE-EPGGAAVREVYEEAGVKGKLGRLLGVFEQNQDPKHRTYVYVLTVTELLEDWEDSVSIG--------RKREWFKVEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSMAPSSPDSDP----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96G61-1", "uniprot_id": "NUD11_HUMAN", "id": "Q96G61-1", "name": "Diphosphoinositol polyphosphate phosphohydrolase 3-beta", "aln": "--------------MKCKPNQTRTYD-PEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEE-EPGGAAVREVYEEAGVKGKLGRLLGVFEQNQDRKHRTYVYVLTVTELLEDWEDSVSIG--------RKREWFKVEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSMAPSSPDSDP----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R2U6-1", "uniprot_id": "NUDT4_MOUSE", "id": "Q8R2U6-1", "name": "Diphosphoinositol polyphosphate phosphohydrolase 2", "aln": "--------------MKFKPNQTRTYD-REGFKKRAACLCFRSEQEDEVLLVSSSRYPDQWIVPGGGMEPEE-EPGGAAVREVYEEAGVKGKLGRLLGIFE-NQDRKHRTYVYVLTVTEILEDWEDSVNIG--------RKREWFKVEDAIKVLQCHKPVHAEYLEKLKLGCSPTNGNSSVPSLPDNNALFVTAAPPSGVPSSIR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99MY2-1", "uniprot_id": "NUDT4_RAT", "id": "Q99MY2-1", "name": "Diphosphoinositol polyphosphate phosphohydrolase 2", "aln": "--------------MKFKPNQTRTYD-REGFKKRAACLCFRSEQEDEVLLVSSSRYPDQWIVPGGGVEPEE-EPGGAAAREVYEEAGVKGKLGRLLGIFE-NQDRKHRTYVYVLTVTEILEDWEDSVNIG--------RKREWFKVEDAIKVLQCHKPVHAEYLERLKLGCSPTNGNSTVPSLPDNNALFVTAAPPSGVPSSIR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NZJ9-1", "uniprot_id": "NUDT4_HUMAN", "id": "Q9NZJ9-1", "name": "Diphosphoinositol polyphosphate phosphohydrolase 2", "aln": "-------------MMKFKPNQTRTYD-REGFKKRAACLCFRSEQEDEVLLVSSSRYPDQWIVPGGGMEPEE-EPGGAAVREVYEEAGVKGKLGRLLGIFE-NQDRKHRTYVYVLTVTEILEDWEDSVNIG--------RKREWFKVEDAIKVLQCHKPVHAEYLEKLKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSVR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99321-1", "uniprot_id": "DDP1_YEAST", "id": "Q99321-1", "name": "Diphosphoinositol polyphosphate phosphohydrolase DDP1", "aln": "MGKTADNHGPVRSETAREGRENQVYSPVTGARLVAGCICLTPDKK-QVLMITSSAHKKRWIVPKGGVEKDEPNYETTAQRETWEEAGCIGKIVANLGTVEDMRPPKD----WNKDIKQFENSRKDSEVAKHP------PRTEFHFYELEIENLLDKFPECHKRHRKLYS-YTEAKQNLIDAKRPE----LLEALNRSAIIKDDK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:.:.*. * : *.*:*: : : :**:::** : .:**** **:* :* : :* **. **** *.: :* .* : *. : :.:. :. :** : *:. : . * : * . * : . . ", "identical_positions": 34, "similar_positions": 49, "identity": "16.67%" }, { "cls_id": "homologset.agr.SGD:S000005690", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7L5D6-1", "uniprot_id": "GET4_HUMAN", "id": "Q7L5D6-1", "name": "Golgi to ER traffic protein 4 homolog", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAAAMAEQESARNGGRNRGGVQRVEGKLRASVEKGDYYEAHQMYR-TLFFRYMSQSKHTEARELMYSGALLFFSHGQQNSAADLSMLVLESLEK--AEVEVADELLEN--LAKVFSLMDPNSPERVTFVSRALKWSSGGSG-KLGHPRLHQLLALTLWKEQNYCESRYHFLHSADGEG---------------------------------------------------------------CANMLVEYSTSRGFR----SEVDMFVAQ-------------AVLQFLCLKNKSSASVVFTTYTQKHPS-IEDGPPFVEP------------LLNFIWFLLLAVDGGK-LTVFTVLCEQYQPSLRRDPMYNEYLDRIGQLFFGVPPKQTSS-------------------YGGLLGNLLTSLMGSSEQEDGEESPS----DGSPIELD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D1H7-1", "uniprot_id": "GET4_MOUSE", "id": "Q9D1H7-1", "name": "Golgi to ER traffic protein 4 homolog", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAAAMAEQEGARNGARNRGGVQRVEGKLRASVEKGDYYEAHQMYR-TLFFRYMSQSKHAEARELMYSGALLFFSHGQQNSAADLSMLVLESLEK--AEVDVADELLEN--LAKVFSLMDPNSPERVAFVSRALKWSSGGSG-KLGHPRLHQLLALTLWKEQNYCESRYHFLHSSDGEG---------------------------------------------------------------CANMLVEYSTARGFR----SEVDMFVAQ-------------AVLQFLCLKNKNSALVVFTTYTQKHPS-IEDGPPFVQP------------LLNFIWFLLLAVDGGK-LAVFTVLCEQYQPSLRRDPMYNEYLDRIGQLFFGVPPKQTSS-------------------YGGLLGNLLSSLMGSSEQEEGEESQD----DSSPIELD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VN19-1", "uniprot_id": "GET4_DROME", "id": "Q9VN19-1", "name": "Golgi to ER traffic protein 4 homolog", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAAETGPIASGSAVSTGQRG-VSRVLAKLSQSLAGGEFYEAHMMYR-TLYFRYTAQKRYQDCLELLFDGAQQLIAKEQESSAADLCLLLVDTLEKRGPQAEDTDNFLWVPRLGALIRGLNSATVERETLIQRTIKWSTALHG-QYGHPVLHKLIAHVFWTEGNIESARHHYLLCQDGSL---------------------------------------------------------------CGRVLIEISQSRGFQ----GEMDLFLVQ-------------AVLQQLSLKDRKTAEDTFTEYTRYHAKLLKHEFPYKEP------------LVNFLYFLFRLIDAKR-VAGFRALRKLYDPSLKRDTSFLKYVAKIGVLYFDEHPEAAHSGPPG---------------LGGMFGDIFNRLMAGFEEDDADDHDTTLRRQNENNELE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12125-1", "uniprot_id": "GET4_YEAST", "id": "Q12125-1", "name": "Golgi to ER traffic protein 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVPAESNAVQAK----------LAKTLQRFENKIKAGDYYEAHQTLR-TIANRYVRSKSYEHAIELISQGALSFLKAKQGGSGTDLIFYLLEVYDL--AEVKVDDISVAR--LVRLIAELDPSEPNLKDVITGMNNWSIKFSEYKFGDPYLHNTIGSKLLEGDFVYEAERYFMLGTHDSM---------------------------------------------------------------IKYVDLLWDWLCQVDDIEDSTVAEFFSR-------------LVFNYLFISNISFAHESKDIFLERFIEKFHPKYEKIDKNGYEIVFFEDYSDLNFLQLLLITCQTKD-KSYFLNLKNHY---LDFSQAYKSELEFLGQEYFNIVAPKQTN----------------------FLQDMMSGFLGGSK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A8I6A5F2-1", "uniprot_id": "A0A8I6A5F2_RAT", "id": "A0A8I6A5F2-1", "name": "", "aln": "MWRVFVPRPGRCGRGLRRRREAAWSEPVNMDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHRLEPVFDSPRMSRRSLRLITTTAAYSSGDGQTVDTHISTSRATPAKGRETRTVKQRSASKPAFSINHLSGKGLSSSTSHDSSCSLRSATVLRHPVLDESLIREQTKVDHFWGLDDDGDLKGGNKAATQGNGELAAEVASSNGYTCRDCRMLSARTDALTAHSAVHGPTSRVYSRDRTLRPRGASFYLDRTLWLAKYTSSSFASFIVQLFQVVLMKLNFESETYKLKGYESRAYESQSYETKSHESEAHLGHCGRMTAGELSRVDGESLCDDCKGKKHLETHTTTHSQLSQPHRAAGAMGRLCTYTGDLLVRALRRTRAAGWSVAEAMWSVLWLAVTAPGKAASGTFWWLGSGWYQFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGFSLWGQGNFFSLLPMLNWTAMQPAQRVDNPKDMHRPGPLSPSPPLKVDPMASQWPQESDMGQKIASLSAQCHNHDERLAELTVLLQKLQIRVDQVDDGREGLSLWVKDMVGQHLQEIGSIEPPDAKTDFLTLHHDHEVRLSSLEDVLRKLTEKSEAIQKELEETKLRAGSRDEEQPLLDRVQHLELELNLLKSQLSDWQHLRSSCEQADARIQETVQLMFSEDQPGGSLEWLLQKLSSRFVSKDELQVLLHDLELKLLQNITHHITVTGQAPTSEAIVSAMSQAGISGITEAQAHIIVNNALRLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALLSLFGVPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSAPRDFAVYGLETEYQEEGQPLGRFTYDQEGDSLQMFHTLERPDQGFQIVELRVLSNWGHPEYTCLYRFRVHGEPIQ", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . : ** : . * . : . : .* :.: . :.: . :. : : . : *.. .. . :. . : : . : :. :: * . . * : :: : : : : * : : . : .. . : ::: : : ", "identical_positions": 8, "similar_positions": 64, "identity": "0.85%" }, { "cls_id": "homologset.agr.SGD:S000005692", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHR0-1", "uniprot_id": "D3ZHR0_RAT", "id": "D3ZHR0-1", "name": "Transcriptional protein SWT1", "aln": "---MLLCTTSAHKLETVYDHKFPKMSIKESCGKEEKSQKK-QTTSSPTFDEDKKEGE-------------ISAGSTSSEHCVKPVSTKKRKLKPDDTDIVYYNTNRKHSMKRLNVEVGLPKKRPKFSSSTQ------VASYLNSNQITLHSSSSDGAK-------DTKLKDCKLTNIGSKLDYEIKSRSL----------------IKITKDMKSKAEDQTKE--KNWPSLLIQK-KMKELKKEKNN--KDSSE---------ELEKCTKNQPPQNYNFSNIIKEPLESGRKKIS---FKIPKKSSSALQKLAEENIFSVDSSKSKSKQEGKEHLQSHRVS------LSLERHKTENLFSESTHKHTVCER------RREYHLEHQETNGSDSKENCAQSFETPCSSVSSETIQDTDEEMQIVEELHAARVGKSVDLPAGPPSGELMSMEIDLVEDDVHSSADILSNTASDKKLLIVIDTNILMNHLKFVRILKTTEIPGFDTLVLIIPWVVMQELDRMK-AGKLLKHVQHKAVPAIHFINDSLKSQDRKLWGQSLQLASQKLYGLSDEN-------NDDRVLKCCLQYQELFPCSLVILCTDDRNLRSKGLISGVKSLSKEELDTEILNLTLNTDLCHQPYISKQ-QLKAEVPPTEETSKEESTNSGLSILLER-----IICDLEKCLGTALSSILETEMKIAFGNLWMEVLYLKPPWTLIN-LLQCFKKHWLAVFGLVMENNLLVTIESLYDNLSKANKAVDFTTVKFLLQDSKSLLHAFSTRSNYDGILPQTFAQVNKLLQVLAEVKTKLKPNSSESTMSKKQEDT-LMKLHNQEVTVFLDSHPPQFTRHQEIWSVLENVWTSIYQNSTDVFQTLDSSSTLTTSKIAS----FEEAFIYLQKLMVAVKDILEGIQRILAPNSNCQDVETLYNFLIKYEVN-KNVRFTAQELYDCVSQTEYREKLTIGCRQLIEMEYTMQQCSASVYMEAASRGWCEGMLNSRT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBQ9-1", "uniprot_id": "SWT1_MOUSE", "id": "Q9DBQ9-1", "name": "Transcriptional protein SWT1", "aln": "---MLLCTTSAHKLETVYDHKFLKMSIKESCAKEEKSQKK-QTISSPTFNEDKKKGE-------------ISAGSTSSEHGVQPVSTKKRKLKADDTDNVYYNANRKNS-KRLNVEVFIPKKRLKFSSSTQ------AVSYLNNNQMTSHSCSSNGTK-------DTKVKDCKLTNIGSKLNYEIKNHSR----------------IKITKDMKSKPVDQTKE--KNWPSLLIQK-KMKELKKEKNN--KDSSE---------ELEKCKKNHLPQNYNFSNMIKESFESGRKKIS---FKIPKKSSTTLQKLVEEKIFTIDSSKSKSKQEEKQHLQSHQMS------LNLARHKTENSFSDSTHKQSVCER------IRKDHCEHQGTSSSDSKENHAQSFETPCSSVSSEDTQDADEEMQIVEELHAARVGRSVDLPVVPPSGELMSMEIDLVDEDAHPSA---AHTASDTKLLIVMDTNVLMNHLKFVKILKTTEIPGFDTLVLIIPWVVIQELDRMK-AGKLLKHVQHKAVPAIHFINNSLKSQDRKLWGQSLQLASQKLYGLSDEN-------NDDRVLKCCLQYQQLFPCSLVILCTDDRNLRTKGLISGVKSLSKEDLDTEILNLTLNTDLCHQPCISKQ-QLNAEVPPAKETPKEGAANSGLSILLER-----IICDLEKCLGTALSSILETEMKIAFGNLWMEVLYLKPPWTLIN-LLQCFKKHWLAVFGLVMENNLLVTVESLYENLCKANKAVDFTTVKFLLQDSKSLLHAFSTRSNYDGVLPQTFAQVNKLLQVLAEVKTKLKPSSSESTRSKEQEDTSLVKLHNQDVNVFLDSNLPQATRHQEIWSVLESVWMSIYQNSTDVFQTLDSSSTLTTSKIAS----FEEAFVYLQKLMVAVKDILEGIQRILAPNSNYQDVETLYNFLIKYEVN-KNVKFTARELYDCVSQTEYRERLTIGCRQLIEMECTMQQCSASVYMEARSRGWCEDMLNNRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T5J6-1", "uniprot_id": "SWT1_HUMAN", "id": "Q5T5J6-1", "name": "Transcriptional protein SWT1", "aln": "------------------------MSSKESCGKKETSQRKDTTTSSPNFGEKDKKER-------------KTPASSTSSSSIRSVSSEKRKLKSDHTDVLYYNIKRRQGLKRLSVEIDTLRRRPKIGSSSQRPIKLKEASYSNDNQIILQSPSSNGTKKDIHKCVDFKPKDIKLTNAGSKLDHGIKSLSS----------------PKIASDVKPKAEGQASE--NKWSHLLVQREKMKELKKGRNSKFRDNSEK-------CVLEKWKRNQFSQDYNSNKIIKEPLGSRRQKIS---FKIPIKSRDTLQKLVEENVFNIDSNNSKTKQEEREYLESSQVS------LNVTRQKTEHLLSDFTYKRTVHEW------KRKHHYDHQESNDSHSRENLTQSFEAPCCSVSSESIQDADQEMQIVEELHAARVGKSVDLP-----GELMSMEIDL-EDDVHSSS---ANNTSDRKLLIVIDTNILMNHLKFVRILKTTEVPGFDKLVLIIPWVVMQELDRMK-EGKLLKRAQHKAIPAVHFINDSLKNQDRKLWGQSIQLASQKHYGLSDEN-------NDDRVLKCCLQHQELFPCSFVILCTDDRNLRNKGLISGVKSLSKEELSAELLHLSLNTDVCHQPCIPKQ-QLKAETTPLKESYKEESTNSGLSILLES-----IVSDLEKSLGTGLSSILETEMKIAFGNLWMEILYLKPPWTLLH-LLQCFKKHWLAVFGLVMEKNLLLTIESLYKNLRKANKAVDFTTVKFLLQDSRSLLHAFSTRSNYDGILPQTFAQVNNLLQTFAEVKTKLKPNSSENTVTKKQEGTSLKNSHNQEITVFSSSHLPQPSRHQEIWSILESVWITIYQNSTDVFQRLGSNSALTTSNIAS----FEEAFICLQKLMAAVRDILEGIQRILAPNSNYQDVETLYNFLIKYEVN-KNVKFTAQEIYDCVSQTEYREKLTIGCRQLVEMEYTMQQCNASVYMEAKNRGWCEDMLNYRI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P2Z5-1", "uniprot_id": "A0A8M9P2Z5_DANRE", "id": "A0A8M9P2Z5-1", "name": "Transcriptional protein SWT1", "aln": "MASKKSKKKKNKKEEKLSSRLYEDEKEERDTKRCISSKSKHKHHHCVSFDKDEAKGRRATVSLPEKTFEAILNQTDAGESKSKKKRSKINKNKGTEKSKPVLNLPNKHEKKCVNAKDKHKNASPQISKNKAKNQPSSEEASKKREKLVSRKPPSEDLRWTLAKDDCLKLQQRRMKPVKRRLSQELHAQPKRRNIKNGTDVAQTNCQFKSPTEMRKKLVGKRSKKINQPAGAILQNSPGKTMKNNSKAAMSAVKHVRSKLKLLEDISPKKKDRAKQRKTLGVLLGEKSPSFCGSIANTKFKIP-KLPSAVKAQTNTNLFNVNSSDSRTQITTQPSLPGSSPAKPQNFLLRQQMQKPEEVSSQTSYELSSLCSSHHSYVSRQVQLVYTDDKGEVTMTDGASHNDQHISSQKAPKTYDFDHEVHLVEELNLARSERRLEVNVEQNCGELTCMDIDPPEEGANTIL-------KKQALLIVLDTNVLLSHLEFVKKIRSRGFGGLGFPTLLIPWVVLQELDYLK-SGKLSSKVEDKARPAVHYIYSCLKNQEPRLIGQSMQLASQADCGPGVVN-------NDDRVLQCCLQYQALYPEGALVLCTNDKNLCSKALLSGVKAYSKADLVIEAEGTTSKIFEPDQQYICARPAVMSPAGPVEKAEKQGSQDNSNSIVVDEQDLIEYVSLLESSLQAALSEVLTEEMKAAYGDLWIEIVYVKPPWSLEG-LLKCFKKHWIAVFGLIINRSLLSCVEMLSDCLCSD-RSVEHTSILSAVSLAKELLSALSGRSQYSGHVAHALSTLHTLQQRLQSPKALLESGEADNE-------------DSLMAEIEDDVALPPSTSHQEVWALFESIWNNVCQISSSLFSALHYTPGTTEPSLRSTSPPPQEALSCLQRLSTALKQLLEALQRLLSADSSVQDAQSLLSFIQTSEIAAMEPRFTAKSLFDCVSQQEYREKLCVGGAQLSELCVNLDQCAAAARSWP--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KUW4-1", "uniprot_id": "Q7KUW4_DROME", "id": "Q7KUW4-1", "name": "", "aln": "-------------------------------------------------------------------------MSLGGESKHTPKSSNLRPLDDDQLVRIISTPRPSNGVSQHPAQDRLKRLQGQLKRVQD-----NEKEQGTTKRITHSSSASRRSS-------ASTSTPQRLLKFPPKVAMNAWEKPK------------------ALVDAN----------------------------------------------------RLKAGRTQTAYQRLMLLRASLQQK---------QLYEERNNNIVAKINEEVIEKQPEACN--ITNPSAFDGSTAS----------DMEVEPMEWQESIEEEAAQN----------DQDEAKKGDDTLLMLPAESIEEEAPQKGQDEAKEEDDTILMLQAADAEELPPRLEDY-----------------------------------MYFVLDTNVLIHNHKFVERLTDVVLPGTVGSMLYLPYIVIKELDKLK-SKYQSDCLQR--VIAMRAIRFLNTKFDESFQIQAQSALEEADHLIKIDC-------PDDSILNCCLQLQAQVPH--MILLTNDANLRLKANASNIQVSCRSDLMSTYVDEFAGFGD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12104-1", "uniprot_id": "SWT1_YEAST", "id": "Q12104-1", "name": "Transcriptional protein SWT1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDEKRAFPK-------------------------------------------------------------------------------GNNHIRSETFNGSVSHKISES------------IKDIASLRPHGKYTVQDIDNIIASTSSHENRGQSGDSNG---------------CINHDEEGDIP--------------MCDLNDESDVEMISEYLSSQREMEAQSVANYMPKINDDLPLLNPPTLKT--------------------------------------------AFVVDTNFIISHLNTLEKLRS--LSSTYHHLIIVPTTVIQELDGLKKSPDIARDNDDTTNQEHDRTIGTLARWGNDWIYKNLANLDSGLIGQKLKQSLNPGSLKDDSILDCCLYFKEILNC-FVILLSNDKNLCTKALTEDILTVSFRKNMDAKIIAMRAYEENQLRFANLRDSTVNNFDQNVTSYAHIPGIETPPLQFDK-----VSQNVFEQVKETIFFAIDHTLRKEYGEDIGFIDYNPDKLTTIENASNYIYLFWVSVFSELFTCSKIKKNEWKSLPTVLKSKPTNLNDLRTFEQFWETVLHFLFSKFTNE--------EKQSLEKQIHEWKTSINAIST--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .. : . : : : : : . . . : . . . . . :. : ::: :*:***.:: : : :. : . . : :* *::*** :* : : .. ** :*.*** : ::* ::* ** *. ..: . . ", "identical_positions": 21, "similar_positions": 60, "identity": "2.09%" }, { "cls_id": "homologset.agr.SGD:S000005693", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62857-1", "uniprot_id": "RS28_HUMAN", "id": "P62857-1", "name": "Small ribosomal subunit protein eS28", "aln": "MDTSRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLTLLESEREARRLR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62858-1", "uniprot_id": "RS28_MOUSE", "id": "P62858-1", "name": "Small ribosomal subunit protein eS28", "aln": "MDTSRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLTLLESEREARRLR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62859-1", "uniprot_id": "RS28_RAT", "id": "P62859-1", "name": "Small ribosomal subunit protein eS28", "aln": "MDTSRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLTLLESEREARRLR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PBK3-1", "uniprot_id": "RS28_DANRE", "id": "Q6PBK3-1", "name": "Small ribosomal subunit protein eS28", "aln": "MDASRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDSNRSIIRNVKGPVREGDVLTLLESEREARRLR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W334-1", "uniprot_id": "RS28_DROME", "id": "Q9W334-1", "name": "Small ribosomal subunit protein eS28", "aln": "MD----KPVVWARVMKVLGRTGSQGQCTQVKVEFLGEQNRQIIRNVKGPVREGDILTLLESEREARRLR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAB9-1", "uniprot_id": "Q9VAB9_DROME", "id": "Q9VAB9-1", "name": "Small ribosomal subunit protein eS28", "aln": "MD----KPQ-YARVVEILGRTGSQGQCTQVRVEFLGDQSRQIIRNVKGPVRVGDILSLLETEREARRLR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3E7X9-1", "uniprot_id": "RS28A_YEAST", "id": "Q3E7X9-1", "name": "Small ribosomal subunit protein eS28A", "aln": "MDN--KTPVTLAKVIKVLGRTGSRGGVTQVRVEFLEDTSRTIVRNVKGPVRENDILVLMESEREARRLR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * *:* ::******:* ***:***: : .* *:******** .*:* *:*:********", "identical_positions": 40, "similar_positions": 13, "identity": "57.97%" }, { "cls_id": "homologset.agr.SGD:S000005694", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66H61-1", "uniprot_id": "SYQ_RAT", "id": "Q66H61-1", "name": "Glutamine--tRNA ligase", "aln": "-MATPDSLALFTGLGLSENKARETLKNAALSTQLREAATQAQQTLG-STIDKATGTLLYGLASRLR--DTRRLSFLVGYIANKKIHTELQLSAALEYVRSHPL---DPIDTKDFEQECGVGVVVTPEQIEEAVEATINR-HRPQLLVERYRFSMGLLMGEAR--AALRWADGKMIKNEVDMQVLHLLGPKMEADLEKKPKVAKARLEETDRKTAKDVVENGEVAGQTLSLMEQLRGEALKFHKPGENYKTPGYVTTPHTMDLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAIYDMVTWLGYTPYKVTYASDYFDQLYAWAVELIRRGQAYVCHQRGEELK-----------GHNPLPSPWRDRPIEESLLLFEAMRKGKFAEGEATLRMKLVMEDGK---MDPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGRLNLHYAVVSKRKILQLVAAGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLEPLQVVITNFPAPKPLDIRVPNFPADETKGFHQVPFASTVFIERTDFKE-ESEPGYKRLAWGQPVGLRHTGYVIELQHVVRG-SSGCVECLEVTCR----RADAGEKPKAFIHWVSQP-------LVCEIRLYERLFQHKNPEDPVEVPGGFLSDLNPASLQVIKGALVDCSVA------------------------LAKPFDKFQFERLGYFSVDPDSHQGQVVFNRTVTLKEDPGKV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BML9-1", "uniprot_id": "SYQ_MOUSE", "id": "Q8BML9-1", "name": "Glutamine--tRNA ligase", "aln": "-MATPDSLALFTGLGLSENKARETLKNEALSTQLREAATQAHQILG-STIDKATGVLLYDLVSRLR--DTRRRSFLVSYIANKKIHTGLQLSAALEYVRSHPQ---DPIDTKDFEQECGVGVVVTPEQIEEAVESTINK-HQLQLLAERYRFNMGLLMGEAR--AALRWADGKMIKNEVDMQVLHLLGPKMEADLVKKPKVAKARLEETDRKTAKDVVEKGEVAGQTLSLMEQLRGEALKFHKPGENYKTPGYVITPYTMDLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAIYDMVTWLGYTPYKVTYASDYFDQLYAWAVELIHGGLAYVCHQRVEELK-----------GHNPLPSPWRDRPKEESLLLFEAMRKGKFAEGEATLRMKLVMEDGK---MDPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALKVYCPVQWEYGRLNLHYAVVSKRKILQLVAAGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDAAPRAMAVLEPLQVVITNFPAPKPLDIRVPNFPADETKGFHQVPFASTVFIERSDFKE-ESEPGYKRLASGQPVGLRHTGYVIELQNIVRG-SSGCVERLEVTCR----RADAGEKPKAFIHWVSQP-------LVCEIRLYECLFQHKNPEDPVEVPGGFLSDLNPASLQVVEGALVDCSVA------------------------LAKPFDKFQFERLGYFSVDPDSHQGQIVFNRTVTLKEDPGKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47897-1", "uniprot_id": "SYQ_HUMAN", "id": "P47897-1", "name": "Glutamine--tRNA ligase", "aln": "-MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLG-STIDKATGILLYGLASRLR--DTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPL---DPIDTVDFERECGVGVIVTPEQIEEAVEAAINR-HRPQLLVERYHFNMGLLMGEAR--AVLKWADGKMIKNEVDMQVLHLLGPKLEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGENYKTPGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELK-----------GHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGK---MDPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADETKGFHQVPFAPIVFIERTDFKE-EPEPGFKRLAWGQPVGLRHTGYVIELQHVVKG-PSGCVESLEVTCR----RADAGEKPKAFIHWVSQP-------LMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASLHVVDAALVDCSVA------------------------LAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13AB14-1", "uniprot_id": "A0AB13AB14_DANRE", "id": "A0AB13AB14-1", "name": "Glutamine--tRNA ligase", "aln": "---MADVVSSFMSIGLSEQKAKETLKNETLSSTLKKAIDLAQGQLGSSAIDKITGTLLYSMVTRLK--DTNRLPFLTKYIISRKITTELQLSAALDFVKSHPQ---GDVDQRKFEVACGVGVVVTPEQIEDAVELIIRK-HKDQLLAERYRFNMGILMGEAR--ATLKWADGKIVKNEVDMQVLHLLGPKTEADLEKKSKAVKPKAPEKDVKIEQASAVNGDGNIENKSLMEQLRGEALKFHKPGENYKTEGYVVTPNTMNLLKKHLEETGGQVRTRFPPEPNGILHIGHAKAINFNFGFAKANNGICFLRYDDTNPEKEEEKYFTAIKDMVEWLGYEPYAVTHASDNFQRLYNLAVDLIRRGHAYVCHQRGEELK-----------GHNVPSSPWRERPVEESLVLFEHMRKGMFAEGEATLRMKMVMEDGK---MDPVAYRIKYTPHHRTGDTWCIYPTYDYTHCLCDSIENITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGRLNLTYTVVSKRKIIKLVETGVVRDWDDPRLFTLTALRRRGFPPQAINNFCARVGVTVAQTTMEPHLLEACVREVLNDTAPRAMAILEPLKVTIINLPTNAQKELRVPDFPANEARGSHVVPFSKTIFIEQSDFRE-VMEKGYKRLTPDQSVGLRYAGYVISVQRVIKD-DRGKVCELEVTCV----SSDTAEKPKAFIHWVSEP-------LLCEVRLYERLFLHKNPEDPAEVPAGFLSDINPNSLTVIESALVDRSVG------------------------KAKVFDKFQFERVGYFSVDADSTPEKLVFNRTVTLKEDPGKI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y105-1", "uniprot_id": "SYQ_DROME", "id": "Q9Y105-1", "name": "Probable glutamine--tRNA ligase", "aln": "-MAGDDLIAKFQALGMSEQKAKETLKNANVTKNLQLSLAAA----GSATLSDGTGMLIYHMATKLKPQTADHLPLLVRYIVEHKLDNTQRVDAALEYLLKCGQSLNANIDLQALEKECGVGVVVTPEQIERTVQAKIKASYKEALLEQRYHFNSFKILQDVR--GELKWADAKSVKAAIDVEIFDLLGPKTEADLKPQTKANDKPKAAKPKAEVTPAAQTAEAASDGATTISELMKTKVHFHAPGENFKADGYVVTEHTERLLKEHLARTGGKVHTRFPPEPNGILHIGHAKAININFGYAAAHDGVCYLRYDDTNPEKEEEKFFLAIKEMVEWLGYKPFKITYSSDNFQQLYEWAVVLINKGLAYVCHQKAEELK-----------GFNPKPSPWRERPIEESLRLFEDMKRGKIDEGAATLRMKVTLEEGK---MDPVAYRIKFISHHRTGSDWCIYPTYDYTHCLCDSLEDITHSLCTKEFQSRRSSYYWLCNALGIYCPVQWEYGRLNMNYALVSKRKIAKLITEQIVHDWDDPRLFTLTALRRRGFPAEAINNFCAQMGVTGAQIAVDPAMLEAAVRDVLNVTAPRRLVVLEPLKVTIKNFPHAAPVQLEVPDFPQNPQQGTHKITLDKVIYIEQGDFKL-EPEKGYRRLAPKQSVGLRHAGLVISVDEIVKDPATGQVVELICTSQ----PAEQAEKPKAFVQWVSQP-------IQLEVRLYEQLFKHKNPEDPNEVPGGFLSDISEQSMSVVV-AFADRALN------------------------QAKVYDKFQFERIGFFSVDPDTSANHLVFNRTVGLKEDAGKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13188-1", "uniprot_id": "SYQ_YEAST", "id": "P13188-1", "name": "Glutamine--tRNA ligase", "aln": "MSSVEELTQLFSQVGFEDKKVKEIVKNKKVSDSLYKLIKETP---SDYQWNKSTRALVHNLASFVKGTDLPKSELIVNGIINGDLKTSLQVDAAFKYVKANGE----ASTKMGMNENSGVGIEITEDQVRNYVMQYIQE-NKERILTERYKLVPG-IFADVKNLKELKWADPRSFKPIIDQEVLKLLGPKDERDLIKKKTKNN---EKKKTNSAKKSSDNSASSGPKRTMFN--EGFLGDLHKVGENPQAY--------PELMKEHLEVTGGKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVSWLGFKPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKEDGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAYRVLNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHVFRPAQREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINTLGVTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDDYEELATIPYRPGTPEFGERTVPFTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIKVSHTVSFKSLEKD-EAGKIIRIHVNYDNKVEEGSKPKKPKTYIQWVPISSKYNSPLRVTETRVYNQLFKS---ENPSSHPEGFLKDINPESEVVYKESVMEHNFGDVVKNSPWVVDSVKNSEFYVEEDKDSKEVCRFQAMRVGYFTLDKESTTSKVILNRIVSLKDATSK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :*:.::*.:* :** :: * : . .. * *:: :.: :: : ::. * . .: . ::.**:.:: :: .***: :* :*:. * *. : :* :**:: :: :.: *:*** : .* :* :::.***** * ** : . . . .. : :. .:* *** :: *:*:** ***:*:********* *****:*** .***:* ::* *:**:******** ::* :* ** ***: *: :*::** *:.** * **. * ***** **:* * : .. *::. *:.* *. *: * * * **** ::. . * :***: .* *** * ******:**** **:*.*******.** *.** ***: : :: *.* ******: :::***** :*: *:.********* *:****.*. ** .* :*** : :: :*:.**. *: ::** : :*:.:.* : *:. :* * * : :.: .:**: ** : : **: *.*** .. .:... : :. * : : . .. :***::::**. . * *:*: ** *:* . * ***.*:. * * :. : . :* :** *:*:*::* :: ::::** * **: ..* ", "identical_positions": 248, "similar_positions": 219, "identity": "29.67%" }, { "cls_id": "homologset.agr.SGD:S000005697", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CI15-1", "uniprot_id": "SPHK1_MOUSE", "id": "Q8CI15-1", "name": "Sphingosine kinase 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPVE--------------CPRGLLPRPCRVLVLLNPQGGKGKALQLFQSRVQPFLEEAEITFKLILTERKNHARELVCAE--ELGHWDALAVMSGDGLMHEVVNGLMERPDWETAI-QKPLCSLPGGSGNALAASVNHYAGYEQVTNEDLLINCTLLLCRRRLSPMNLLSLHTASGL---------------RLYSVLSLSWGFVADVDLESEKYRRLGEIRFTVGTFFRLASLRIYQGQLAYLPVGTVASKRPAS-TLVQK--------------------------------------G-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVDTHLVPLEEPVPS-HWTVVPEQDFVLVLVLLHT----HLSSELFAAPMGRCEAGVMHLFYVRAGVSRAALLRLFLAMQKGKHMELD-CPYLVHVPVVAFRLEPRSQRGVFSVDGELMVCEAVQGQVHPNYLWMVCGSRDAPSGRDSRRGPPPEEP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91V26-1", "uniprot_id": "SPHK1_RAT", "id": "Q91V26-1", "name": "Sphingosine kinase 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQPAD--------------CPRGLLPRPCRVLVLLNPRGGKGKALKLFQSRVRPLLEEAEVSFKLMLTERQNHARELVCAE--ELGHWDALAVMSGDGLMHEVVNGLMERPDWESAI-QKPLCSLPGGSGNALAASLNYYAGHEQVTNEDLLINCTLLLCCRQLSPMNLLSLHTASGR---------------QLYSVLSLSWGFVADVDLESEKYRSLGEIRFTVGTFFRLASLRIYQGQLAYLPVGKAASKIPAS-SLAQK--------------------------------------G-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PANTYLVPLEEPVPP-HWTVVPEQDFVLVLVLLHT----HLSTEMFAAPMGRCEAGVMHLFYIRAGVSRAMLVRLFLAMQKGKHMDLD-CPYLVHVPVVAFRLEPRNQRGVFSVDGELMVCEAVQGQVHPNYLWMVSGSSDSPSGRDSQRRPPPEEPI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NYA1-1", "uniprot_id": "SPHK1_HUMAN", "id": "Q9NYA1-1", "name": "Sphingosine kinase 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDPAG--------------GPRGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSE--ELGRWDALVVMSGDGLMHEVVNGLMERPDWETAI-QKPLCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGL---------------RLFSVLSLAWGFIADVDLESEKYRRLGEMRFTLGTFLRLAALRTYRGRLAYLPVGRVGSKTPASPVVVQQ--------------------------------------G-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVDAHLVPLEEPVPS-HWTVVPDEDFVLVLALLHS----HLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYE-CPYLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPNYFWMVSGCVEPPPSWKPQQMPPPEEPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JIA7-1", "uniprot_id": "SPHK2_MOUSE", "id": "Q9JIA7-1", "name": "Sphingosine kinase 2", "aln": "-----------------------------------------MAPPPLLPVAASTPILHG--EFGSYPANGPRFALTLTTQALHIQRLR-PKPEARPRDGLVSLDEVSGCGTLQSRSPEDTA------------------------------AYFCIYTYPRGRRGGRRRATRTFRADGATTYEENRAEAQRWATALTCLLRGVPLSGDQE--------------ITPELLPRKPRLLILVNPFGGRGLAWQRCMDHVVPMISEAGLSFNLIQTERQNHARELVQGL--SLSEWEGIVTVSGDGLLYEVLNGLLDRPDWEDAV-RMPIGVLPCGSGNALAGAVNHHGGFEQVVGVDLLLNCSLLLCRGGSHPLDLLSVTLASGS---------------RCFSFLSVAWGFLSDVDIHSERFRALGSARFTLGAVLGLASLHTYRGRLSYLPATTEPALPIPGHSLPRAKSELVLAPAPAPAATHSPLHRSVSDLPLPLPQPALVSPG--------------------------------------------SPEPLPDLS------------------------LNGGGPELTG----------------DWGG--------------AGDAP------------------------------------------------------------------------------------------------------LSPDPLLPSSPNALKTAQLSPIAEGPPEMPASSGF-LPPTHSAPEASTWG---------------PVDHLLPPLGSPLP--QDWVTIEGEFVLMLGILPS----HLCADLMAAPHARFDDGVVHLCWVRSGISRAALLRILLAMEHGNHFSLG-CPHLGYAAARAFRLEPLTPRGLLTVDGELVEYGPIQAQVHPGLATLLTG----PAGQKPQA--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRA0-1", "uniprot_id": "SPHK2_HUMAN", "id": "Q9NRA0-1", "name": "Sphingosine kinase 2", "aln": "-----MNGHLEAEEQQDQRPDQELTGSWGHGPRSTLVRAKAMAPPPP-PLAASTPLLHG--EFGSYPARGPRFALTLTSQALHIQRLR-PKPEARPRGGLVPLAEVSGCCTLRSRSPSDSA------------------------------AYFCIYTYPRGRRGARRRATRTFRADGAATYEENRAEAQRWATALTCLLRGLPLPGDGE--------------ITPDLLPRPPRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHARELVQGL--SLSEWDGIVTVSGDGLLHEVLNGLLDRPDWEEAV-KMPVGILPCGSGNALAGAVNQHGGFEPALGLDLLLNCSLLLCRGGGHPLDLLSVTLASGS---------------RCFSFLSVAWGFVSDVDIQSERFRALGSARFTLGTVLGLATLHTYRGRLSYLPATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLPQPALASPG--------------------------------------------SPEPLPILS------------------------LNGGGPELAG----------------DWGG--------------AGDAP------------------------------------------------------------------------------------------------------LSPDPLLSSPPGSPKAALHSPVSEGAPVIPPSSGLPLPTPDARVGASTCG---------------PPDHLLPPLGTPLP--PDWVTLEGDFVLMLAISPS----HLGADLVAAPHARFDDGLVHLCWVRSGISRAALLRLFLAMERGSHFSLG-CPQLGYAAARAFRLEPLTPRGVLTVDGEQVEYGPLQAQMHPGIGTLLTG----PPGCPGREP-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TA20-1", "uniprot_id": "A0AB32TA20_DANRE", "id": "A0AB32TA20-1", "name": "sphingosine kinase", "aln": "-------MRSPGPDSPSMTEEALLHGQFG----------GWSSGGGSGSNSNSCPNSPGGVSLPSSPAS-TNYALTLTPTHIHVQRLS-PRAGKQSR-LLLPMAELTGCSCPRSPAP----------------------------------PLLVLYWYPPGRR--RKGVSRHRQVR--AYLAESRAEAEKWNAAIQSLLRGMDVSSTTE--------------FCKSMLPRPRRLLLLVNPFSGRGQAMQWCQTHILPMIREANISYNLIQTERQNHARELIREI--SLPEWDGIVIVSGDGLLHEVINGLMERPDWEQAI-KTPVGILPCGSGNALAGSINHHAGYDMCLREPLLLNCCFLLCRGGVKPLDLVSVTTSPCASSSTSNQNGHPPAPRRLFSFLSVAWGFVSDVDIESERYRGLGSARFTLGTLVRLASLRSYKGRLSYLPPAVVNPSPDATPQPPRRPLSRSITEG-LEGFCRTPIHRTCSDMGLSEQRSLRKDDGERERERERERQERERERERRRDRARGVGVVRASSLAEDREREVEAEEKMEEMSGTSSESTERDECDNIAKNNGNEEENNSGESKIDGQELTNARNLSDTNEVNDCDGSYQTTPPELQHALRKNSAPSSQIINAFFSQPIGADTDQDLELAAYGKEDEDINGTYFQKEAYSLDKSRERALTISSSPFRQSPFKAFKPKTLDQNQNPSRPRPLSLLHQSHSNSLPPKFPSLSPTPPSSPSCASPHSSYLAPRPNTPSSSSPSPSIHSPTPSFNFDLAEPAGPLKNRPHMTSSINLPEDDLLPPLDQPLPT-RDWVTIEGDFVLVLAIYQS----HLGADLLAAPQARFDDGLIHLTFVRAGISRATLLRLFLAMERGAHLSLS-SPYVSHVSARAFRLQPLSPRGTLTVDGELVPYGPLQAQVHPSMARLIVG----DSGIKITRF-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYY8-1", "uniprot_id": "Q9VYY8_DROME", "id": "Q9VYY8-1", "name": "sphingosine kinase", "aln": "MTANTGTSGENLMGNGGKTHEPSTPTSDTEVASGTPTELSEIFFVDNSRRKQSIKIQVKLCPEGVYLRRETEEDDHINEQLIRIDDIIGSRYGRRLKKR--ARGGLNSCR--NPNVPGQEADSEPD---------------------SDNSAYLYIYAYLKKEKPLR----RVQTLRILRFRSSNDYGVNLQTAEMWHHTIRKHKRGN----------------GSSSPADCGKQLLILLNPKSGSGKGRELFQKQVAPLLTEAEVQYDLQITTHPQYAKEFVRTRRDLLTRYSGIVVASGDGLFYEVLNGLMERMDWRRACRELPLGIIPCGSGNGLAKSVAHHCNEPYEP--KPILHATLTCMAGKSTPMDVVRVELATRDKHF------------VMYSFLSVGWGLIADIDIESERLRSIGAQRFTLWAIKRLIGLRSYKGRVSYLLGKGKKEPPVEAARELPAESTAAGIRSSLPLNAGEFHDLPEEEEGEAVLDGEQFADAISLDRSV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YRQHADSWHSAMSRRTAYYSLGGPSMRSNRSRMSISQRIEAANAEFAER----------------VPTGTIPPLQMPLLSSDGWICEDGDFVMVHAAYTT----HLSSDVFFAPESRLDDGLIYLVIIRRGVSRHQLLNFMLNLNAGTHLPIGEDPFIKVVPCRAFRIEPSSSDGILVVDGERVEYGPIQAEVMPGLINVMTTSGQ-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZW0-1", "uniprot_id": "Q9VZW0_DROME", "id": "Q9VZW0-1", "name": "sphingosine kinase", "aln": "-------MSESLDKTTSPSSASSRATPPGTQDADEGHDVSDTFYTSQ-RKKGSHVFRVRLDATGFTLQRESPGGSIVKEQHVRISDIVGARCMRPKKSRRLAMSGACACSSGNPNSPAISASGDHHRPATTPSKCSTNSRDNIPSDGGDVSAFLYVFAYVLKKRSLRSELHRERTVLTLRFRSFDTFEDNMREADRWYRSLRWQLHRTLEE-----------IFVAPTVDERRRRVLVLLNPKSGSGDAREVFNMHVTPVLNEAEVPYDLYVTKHSNFAIEFLSTR--CLDAWCCVVAVGGDGLFHEIVNGLLQRQDWAHVLPHLALGIIPCGSGNGLARSIAHCYNEPYFS--KPVLGAALTVISGRSSPMDVVRVQLQSRS----------------LYSFLSIGWGLISDVDIESERIRMLGYQRFTVWTLYRLVNLRTYNGRISYLLT-DHEVSSTHSATGYAAQRRMQSSRSCN-THIDMLNGPAPIYHSSAEYLPQEFADVISLETSINQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SFRSRCDSWLSGGSRRSFYYSIS-ESIYHSLADESEFAGLAAASLENRQQN--------------YGPASELPDLNEPLSEDQGWLVEEGEFVMMHAVYQT----HLGIDCHFAPKAQLNDGTIYLILIRAGISRPHLLSFLYNMSSGTHLPESHDDHVKVLPVRAFRLEPYDNHGIITVDGERVEFGPLQAEVLPGIARVMVPK-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12246-1", "uniprot_id": "LCB4_YEAST", "id": "Q12246-1", "name": "Sphingoid long chain base kinase 4", "aln": "-------MVVQKKLRAILTDEGVLIKSQSHHMFNKHGQLRSGDSLSLLSCLSCLDDGTLSSDGGSFDEDDSLELLPLNTTIPFNRILNAKYVNVGQKGFNNGKISSNPFQTENLSSSSENDDVENHSLSNDKAPVSESQSFPKKDKWDTKTNTVKVSPDDSQDNSPSLGIKDNQQLIELTFAVPKGHDVIPQKLTLLIDHVSRKSRANTGEENISSGTVEEILEKSYENSKRNRSILVIINPHGGKGTAKNLFLTKARPILVESGCKIEIAYTKYARHAIDIAKDL--DISKYDTIACASGDGIPYEVINGLYRRPDRVDAFNKLAVTQLPCGSGNAMSISCHWTN---------NPSYAALCLVKSIETRIDLMCCSQPSYMN------------EWPRLSFLSQTYGVIAESDINTEFIRWMGPVRFNLGVAFNIIQGKKYPCEVFVKYAAKSKKELKVHFLENKDKNKGCLTFEPNPSPNSSPDLLSKNNINNSTKDELSPNFLNE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DNFKLKYPMTEPVPR--DWEKMDSELTDNLTIFYTGKMPYIAKDTKFFPAALPADGTIDLVITDARIPVTRMTPILLSLDKGSHVLEP---EVIHSKILAYKIIPKVESGLFSVDGEKFPLEPLQVEIMPMLCKTLLRNGRYIDTEFESM--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:::** .* * . : : *.: *: : * ..* :: : : :. .***: :*::*** * * . . .: :* ****.:: : . : :::: . *.** :*.::: *:.:* * :* **.: . : : * .: : *: : ::. : :: : * . * : * :. : :: :. * *. : *::: * * : **** . .:* :: * : ", "identical_positions": 49, "similar_positions": 89, "identity": "5.11%" }, { "cls_id": "homologset.agr.SGD:S000005699", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DAR7-1", "uniprot_id": "DCPS_MOUSE", "id": "Q9DAR7-1", "name": "m7GpppX diphosphatase", "aln": "MADTAPQL-KRKREQEAEEAETPSTEEKEAGVGNGTSAPVRLPFSGFRVQKVLRESARDKIIFLHGKVNEDSGDTHGEDAVVILEKTPFQVEHVA--------------QLLTGSPELKLQFSNDIYSTYNLFPPRHLSD---IKTTVVYPATEKHLQKYMRQDLRLIRETGDDYRTITLPYLESQ--SLSIQWVYNILDKKAEADRIVFENP---DPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIRSLRDLTPEHLPLLRNILREGQEAILKRYQ--VTGDRLRVYLHYLPSYYHLHVHFTALGFEAPG--SGVERAHLLAQVIENLECD-PKHYQQRTLTFALRTDDPLLQLLQKAQQERN-------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K4F7-1", "uniprot_id": "DCPS_RAT", "id": "Q8K4F7-1", "name": "m7GpppX diphosphatase", "aln": "MADTAPQL-KRKREQEAEEAETPSTEEKEAGVGNGTSAPVRLPFSGFRVQKVLRESARDKIIFLHGKVNEDSGDTHGEDAVVILEKTPFQVEHVA--------------QLLTGNPELKLQFSNDIYSTYNLFPPRHLSD---IKTTVVYPASEKHLQKYMRQDLRLIRETGDDYRSLTLPYLESQ--SLSIQWVYNILDKKAEADRIVFENP---DPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIRSLRDLTPEHLPLLRNILREGQEAILKRYQ--VTGDRLRVYLHYLPSYYHLHVHFTALGFEAPG--SGVERAHLLAEVIENLECD-PKHYQRRTLTFALRTDDPLLQLLQKAQQP---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96C86-1", "uniprot_id": "DCPS_HUMAN", "id": "Q96C86-1", "name": "m7GpppX diphosphatase", "aln": "MADAAPQLGKRKRELDVEEAHAASTEEKEAGVGNGTCAPVRLPFSGFRLQKVLRESARDKIIFLHGKVNEASGDGDGEDAVVILEKTPFQVEQVA--------------QLLTGSPELQLQFSNDIYSTYHLFPPRQLND---VKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPHLESQ--SLSIQWVYNILDKKAEADRIVFENP---DPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIRSLRDLTPEHLPLLRNILHQGQEAILQRYR--MKGDHLRVYLHYLPSYYHLHVHFTALGFEAPG--SGVERAHLLAEVIENLECD-PRHYQQRTLTFALRADDPLLKLLQEAQQS---------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PGD6-1", "uniprot_id": "A0A8M1PGD6_DANRE", "id": "A0A8M1PGD6-1", "name": "m7GpppX diphosphatase", "aln": "MAESENGK-------DGKSAAKRPKIDAENEKRNADEQSTDNPVVDFQLTRILRDNPREKSIFIHGKVKD-------QDAVVILEKSPFRQDSLP--------------ELLKTS-QLKLEMQNDVYSTYQLHAPPQLNE---IKTTVMCPATEKHIKKYLHQEVFLLEESGEDYRNLTLPYISGQ--SFSVQWVYNILEKKAEADRIVFEDP---DPDAGFVLLPDFKWDQKQLQDLYLIAIVHRRDIKSLRDLTAEHLTLLTNIRSKGEETIQKKYG--VPPSKLRVYFHYQPSYYHLHVHFTAVEYNVPG--CGVERAHLLSDVIQNLQLD-SSYYHNRSLSFPLRADDGLLQRFREAGKI---------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VNH5-1", "uniprot_id": "Q9VNH5_DROME", "id": "Q9VNH5-1", "name": "m7GpppX diphosphatase", "aln": "MSET----------VDSTEVKSPS-----------------YDLSKFQLKRILTNNSVRKSISLLGTFPDLG----TDDAIVVFEKNAYRESDVATAS---SEESPKKPSYFTADLKVDTEFINNIYGSFQVVPTQDLCS---VKSTVIYPATEKHIEKYSVSQKYLIRETPDLYQRITLPYLTSS--QFSLEWVYNILEHKQETERIVYEDR---DPKTGFILLPDLKWDGRNVETLYLLGIVHKRDIKSLRDLNESHLDLLRNVRQASKDAIAKLYG--INPNQLRMYFHYQPSFYHLHVHINPVRNDAPG--IWCEKSHMLDTVINNLELM-PDYYQRATLPFVLYEGNKLLDLYEQELPIRALTVSSDDKELPDSDSLNVAPPEGFSDEEPEERQCKRIKLGSPEPKEAESAVQACA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12123-1", "uniprot_id": "DCS2_YEAST", "id": "Q12123-1", "name": "Inactive diphosphatase DCS2", "aln": "--------------MGSQDLASLIG--------------------RFKYVRVLDSNPHTKVISLLGSIDGKDAVLTAEKTHFIFDETVRRPSQSGRSTPIFFHREIDEYSFLNGITDLKELTSNDIYYWGLSVLKQHILHNPTAKVNLIWPASQFHIKGYDQQDLHVVRETPDMYRNIVVPFIQEMCTSERMKWVNNILYEGAEDDRVVYKEYSSRNKEDGFVILPDMKWDGINIDSLYLVAIVYRDDIKSLRDLNPNHRDWLIRLNKKIKTIIPQHYDYNVNPDELRVFIHYQPSYYHFHVHIVNIRHPGVGEERGSGMTILLEDVIEALGFLGPEGYMKKTLTYVIGENHDLWKKGFKEEVEKQLKHDGIATSPEKGSGFNTNLG----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *: ::* ... * * : *.. :.: .::::. : . . :. .:. *::* .: * .:: **:: *:: * .: ::.*: : *: :.:*.: . ::** *** . * :*:*::: : . **:::**:**: ::: ***:.* :: .*:*****. .* * .: : * : * : ..**:::** **:**:***: : * : :* **: * . * . :*.: : .. * . : ", "identical_positions": 62, "similar_positions": 105, "identity": "14.73%" }, { "cls_id": "homologset.agr.SGD:S000005700", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQA5-1", "uniprot_id": "MED4_MOUSE", "id": "Q9CQA5-1", "name": "Mediator of RNA polymerase II transcription subunit 4", "aln": "MAASSSGEKEKERMGGVSGMAGLGSTRERLLSALEDLEVLSRELIEMLAISRN------QKLLQLEEENQVLELLIHRDGDFQELMKLALNQGKVHHEMQALEKEVEKRDSDIQQLQKQLKEA-EQILATAVYQAKEKLKSIEKARKGAISSEEIIKYAHRISASNAVCAPLTWVPGDPR-RPYPTDLEMRSGLLGQMNNPSTSGVNGHLPGDALAAGRLPDVLAPQYPWQSNDMSVNMLPPNHSSDFLLE----PPGHNKENEDDVEVMSTDSSSSSSDSD-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q561Q8-1", "uniprot_id": "MED4_RAT", "id": "Q561Q8-1", "name": "Mediator of RNA polymerase II transcription subunit 4", "aln": "MAASSSGEKEKERMGGVSGMTGLGSTRERLLSALEDLEVLSRELIEMLAISRN------QKLLQLEEENQVLELLIHRDGDFQELMKLALNQGKVHHEMQALEKEVEKRDSDIQQLQKQLKEA-EQILATAVYQAKEKLKSIEKARKGAISSEEIIKYAHRISASNAVCAPLTWVPGDPR-RPYPTDLEMRSGLLGQMNNPSTSGVNGHLPGDALAAGRLPDVLAPQYPWQSNDMSVNMLPPNHSTDFLLE----PPGHNKENEDDVEVMSTDSSSSSSDSD-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12343-1", "uniprot_id": "MED4_YEAST", "id": "Q12343-1", "name": "Mediator of RNA polymerase II transcription subunit 4", "aln": "--MSVQDTKAVEFSMGHIRSSSVSLVAEATSNTNSEDKLSKVQLYEDLCRYEDTLSKLVESVDRFKPNLDIAKDLIRTDEALFENVKLLAEYDNIYRNLQKIDKDSEELDSKTRKILEILNECHDELKALPMLEQVEFEKNTILQQRSKINSTELLDYATKLSKFTKIPPTFDKGAVGPNNFIWPAEDALRRGMLAMASLHSKELTR--IPGEEVEETEVPTVPPSQSEEQKGQMAKKEGTP-KTDSFIFDGTAKEVGDEADNTKDKEKEENNDDALDLDLDLFDPDDF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .. * * * :.:. . * .: .: :: . :* * *. .: :.: ::: : :: : **: * : * :** : .::::::* ::*: *: **. ::: : *:*. ::: * .: : * *. ::. *.* *::.** ::* . : ..: . .*. :*:: :* *:*. . *.. .. :**: : .:* * ..* *..:*: : .* :: .*::: *.: :* .* * ..:..: . * * ", "identical_positions": 51, "similar_positions": 115, "identity": "17.65%" }, { "cls_id": "homologset.agr.SGD:S000005701", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LV18-1", "uniprot_id": "F1LV18_RAT", "id": "F1LV18-1", "name": "", "aln": "MAARS-PASLSYRTTGSTCLHPLSQLLGIPLDQVNFVACQLLALSAAFWFRIYLRPGKASPEVRHTLATILGIYFVVFCFGWYAVHLFVLVLMCYGVMVTASVSNIHRYSFFVAMGYLTICHISRIYIFHYGILTTD-----FSGPLMIVTQKITTLAFQVHDGLGR---KAEDLSAEQHRLAVKVKPSLLEYLSYHLNFMSVIAGPCNNFKDYVAFIEGRHIHMKLLEV--NWKERGFQSLPEPSPTGAVIQKLCITLMSLLLFLTLSKSFPVTFLIDDWFVHKANFLSRLWYLYVVMQAAKPKYYFAWTLADAVHNAAGFGFSGID-ADGNSCWDLLSNLNIWKIETATSFKMYLENWNIQTSTWLKCVCYERVPWYP-------TVLTFLLSALWHGVYPGYYFTFLTGVPVTLAARAVRNNYRHHFLA-----SKARKVAYDVVTWAVTQLAVSYTAAPFVMLAVEPTISLYKSMFFFLHILCLLIILLLPVKPR--QPQRQSQSPNSV-----KKKAD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH98-1", "uniprot_id": "MBOA1_MOUSE", "id": "Q8BH98-1", "name": "Membrane-bound glycerophospholipid O-acyltransferase 1", "aln": "MAARP-PASLSYRTTGSTCLHPLSQLLGIPLDQVNFVACQLFALSAAFWFRIYLHPGKASPEVRHTLATILGIYFVVFCFGWYAVHLFVLVLMCYGVMVTASVSNIHRYSFFVAMGYLTICHISRIYIFHYGILTTD-----FSGPLMIVTQKITTLAFQVHDGLGR---KAEDLSAEQHRLAVKAKPSLLEYLSYHLNFMSVIAGPCNNFKDYVAFIEGRHIHMKLLEV--NWTQRGFQSLPEPSPMGAVIQKLCVTLMSLLLFLTLSKSFPVTFLIDDWFVHKANFLSRLWYLYVVMQAAKPKYYFAWTLADAVHNAAGFGFNGMD-TDGKSRWDLLSNLNIWKIETATSFKMYLENWNIQTSTWLKCVCYERVPWYP-------TVLTFLLSALWHGVYPGYYFTFLTGVPVTLAARAVRNNYRHHFLS-----SKARKIAYDVVTWAVTQLAVSYTAAPFVMLAVEPTISLYKSVFFFLHIICLLIILFLPIKPH--QPQRQSRSPNSV-----KKKAD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZNC8-1", "uniprot_id": "MBOA1_HUMAN", "id": "Q6ZNC8-1", "name": "Membrane-bound glycerophospholipid O-acyltransferase 1", "aln": "MAAEPQPSSLSYRTTGSTYLHPLSELLGIPLDQVNFVVCQLVALFAAFWFRIYLRPGTTSSDVRHAVATIFGIYFVIFCFGWYSVHLFVLVLMCYAIMVTASVSNIHRYSFFVAMGYLTICHISRIYIFHYGILTTD-----FSGPLMIVTQKITTLAFQVHDGLGR---RAEDLSAEQHRLAIKVKPSFLEYLSYLLNFMSVIAGPCNNFKDYIAFIEGKHIHMKLLEV--NWKRKGFHSLPEPSPTGAVIHKLGITLVSLLLFLTLTKTFPVTCLVDDWFVHKASFPARLCYLYVVMQASKPKYYFAWTLADAVNNAAGFGFSGVD-KNGNFCWDLLSNLNIWKIETATSFKMYLENWNIQTATWLKCVCYQRVPWYP-------TVLTFILSALWHGVYPGYYFTFLTGILVTLAARAVRNNYRHYFLS-----SRALKAVYDAGTWAVTQLAVSYTVAPFVMLAVEPTISLYKSMYFYLHIISLLIILFLPMKPQA-HTQRRPQTLNSI-----NKRKTD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R3I2-1", "uniprot_id": "MBOA2_MOUSE", "id": "Q8R3I2-1", "name": "Membrane-bound glycerophospholipid O-acyltransferase 2", "aln": "MATTS--------TTGSTLLQPLSNAVQLPIDQVNFVVCQLFALLAAVWFRTYLHSSKTSSFIRHVVATLLGLYLAFFCFGWYALHFLVQSGISYCIMIIAGVESMQQCCFVFALGYLSVCQITRVYIFDYGQYSAD-----FSGPMMIITQKITSLAYEIHDGMFR---KDEELTPSQRGLAVRRMPSLLEYVSYTCNFMGILAGPLCSYKDYIAFIEGRASHVAQPSE--NGKDE-QHGKADPSPNAAVTEKLLVCGLSLLFHLTISNMLPVEYNIDEHFQATASWPTKATYLYVSLLAARPKYYFAWTLADAINNAAGFGFRGYD-KNGVARWDLISNLRIQQIEMSTSFKMFLDNWNIQTALWLKRVCYERATFSP-------TIQTFFLSAIWHGVYPGYYLTFLTGVLMTLAARAVRNNFRHYFLE-----PPQLKLFYDLITWVATQITISYTVVPFVLLSIKPSFTFYSSWYYCLHVCSILVLLLLPVKKSQRRTSTQENVHLSQ-----AKKFDERDNPLGQNSFSTMNNVCNQNRDTGSRHSSLTQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3T1J2-1", "uniprot_id": "MBOA2_RAT", "id": "Q3T1J2-1", "name": "Membrane-bound glycerophospholipid O-acyltransferase 2", "aln": "MATTS--------TTGSTLLQPLSNAVQLPIDQVNFVVCQLFALLAAVWFRTYLHSSKTSSFIRHVVATLLGLYLAFFCFGWYALHFLVQSGISYCIMIIAGVESMHQCCFVFALGYLSVCQITRVYIFDYGQYSAD-----FSGPMMIITQKITSLAYEIHDGMFR---KDEELTPSQRGLAVRRMPSLLEYVSYTCNFMGILAGPLCSYKDYIAFIEGRASHMAQSGE--NGKEE-QHGKAEPSPNAAVTEKLLVCGLSLLFHLTISSMLPVEYNIDEHFQATASWPTKATYLYVSLLAARPKYYFAWTLADAINNAAGFGFRGYD-KNGVARWDLISNLRIQQIEMSTSFKMFLDNWNIQTALWLKRVCYERATFSP-------TVQTFFLSAIWHGVYPGYYLTFLTGVLMTLAARAVRNNFRHYFVE-----PPQLKLFYDIITWAATQITISYTVVPFVLLSINPSFTFYRSWYYCLHICSILVLLLLPVKKSPRKKNTEENAQPSW-----AKKFDERENSLGQNSFSMMNNVCNQNQDTGSRHSALTQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZWT7-1", "uniprot_id": "MBOA2_HUMAN", "id": "Q6ZWT7-1", "name": "Membrane-bound glycerophospholipid O-acyltransferase 2", "aln": "MATTS--------TTGSTLLQPLSNAVQLPIDQVNFVVCQLFALLAAIWFRTYLHSSKTSSFIRHVVATLLGLYLALFCFGWYALHFLVQSGISYCIMIIIGVENMHNYCFVFALGYLTVCQVTRVYIFDYGQYSAD-----FSGPMMIITQKITSLACEIHDGMFR---KDEELTSSQRDLAVRRMPSLLEYLSYNCNFMGILAGPLCSYKDYITFIEGRSYHITQSGE--NGKEETQYERTEPSPNTAVVQKLLVCGLSLLFHLTICTTLPVEYNIDEHFQATASWPTKIIYLYISLLAARPKYYFAWTLADAINNAAGFGFRGYD-ENGAARWDLISNLRIQQIEMSTSFKMFLDNWNIQTALWLKRVCYERTSFSP-------TIQTFILSAIWHGVYPGYYLTFLTGVLMTLAARAMRNNFRHYFIE-----PSQLKLFYDVITWIVTQVAISYTVVPFVLLSIKPSLTFYSSWYYCLHILGILVLLLLPVKKTQRRKNTHENIQLSQ-----SKKFDEGENSLGQNSFSTTNNVCNQNQEIASRHSSLKQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NN55-1", "uniprot_id": "MBOA6_DROME", "id": "Q6NN55-1", "name": "Lysophospholipid acyltransferase 6", "aln": "MLEPP-KFIENDCYNGSRTFTWLADMVGLSVDLVNFLICQISALFLASLFRSMLHPSKVSSKLRHTFALSIGLAFGYFCFGQQAIHIAGLPAICYIVIRTQDPRIVQRAVLLVAMSYLLCVHLMR-QLYDYGSYALD-----ITGPLMIITQKVTSLAFSIHDGFVR---GDEELTKAQQYHAIRKMPSALEYFSYVWHFQSILAGPLVFYKDYIEFVEGYNLLSTPPGNG-NLDSSKREVVLEPSPTKAVIRKVVGSLVCAFIFMKFVKIYPVKDMKEDDFMNNTSMVYKYWYAMMATTCIRFKYYHAWLLADAICNNSGLGFTGYD-KDGNSKWDLISNINVLSFEFSTNMRDAINNWNCGTNRWLRTLVYERVPQQYG------TLLTFALSAVWHGFYPGYYLTFATGAVVVTAARTGRRLFRHRFQS-----TQVTRMFYDILTCLITRVVLGYATFPFVLLEFMGSIKLYLRFYLCLHIISLVTIFILPKFIRGERRLRTSNGNGNVRLSGSGNTKDAVTTSVESTAALTAGNDLNEDKEEDKHAQCKVHTPTQQQPAAGPHKTTVEQPTEQPNNVNLRSRPQQQQPHLEKKAMPPTCARDAVSVPHDQCEMDQLSSKLKEKIEAETKNIEEFIDKTVTETVSGIVEFKNDLMRDIEFPKLKLPGSNGAISLDSSNGGGLRKRNISSVHDNGTDPGHATADLHPPLEENGAAFLKKEIEVINAVVQQAVPAVLSNGHAK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0C7A3-1", "uniprot_id": "MBOA4_MOUSE", "id": "P0C7A3-1", "name": "Membrane-bound ghrelin O-acyltransferase MBOAT4", "aln": "-----------------------MDWLQLFF-LHPLSFYQGAAFPFALLFNYLCILDTFSTRARYLFLLAGGGVLAFAAMGPYSLLIFIPALCAVALVSFLSPQEVHRLTFFFQMGWQTLCHLGLHYTEYYLGEPPPVRFYITLSSLMLLTQRVTSLSLDICEGKVE---APRRGIRSKSSFSEHLW-DALPHFSYLLFFPALLGGSLCSFRRFQACVQR-----------------------SSSLYPSISFRALTWRGLQILGLECLKVALRSAVSAGAGLDDCQRLECIYLMWSTAWLFKLTYYSHWILDDSLLHAAGFGAEAGQ-GPGEEGY--VPDVDIWTLETTHRISLFARQWNRSTALWLRRLVFRKSRRWP-------LLQTFAFSAWWHGLHPGQVFGFLCWSVMVKADYLIHT-FANVCIR-----SWPLRLLYRALTWAHTQLIIAYIMLAVEGRSLSSLCQLCCSYNSLFPVMYGLLLFLLAERKDKRN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B1Q005-1", "uniprot_id": "MBOA4_RAT", "id": "B1Q005-1", "name": "Membrane-bound ghrelin O-acyltransferase MBOAT4", "aln": "-----------------------MDWLQFFF-LHPVSLYQGAAFPFALLFNYLCITESFPTRARYLFLLAGGGVLALAAMGPYALLIFIPALCAVAMISSLSPQEVHGLTFFFQMGWQTLCHLGLHYKEYYLCEPPPVRFYITLSSLMLLTQRVTSLSLDISEGKVE---AAWRGTRSRSSLCEHLW-DALPYISYLLFFPALLGGSLCSFQRFQACVQR-----------------------PRSLYPSISFWALTWRGLQILGLECLKVALRRVVSAGAGLDDCQRLECIYIMWSTAGLFKLTYYSHWILDDSLLHAAGFGSEAGQ-RPGEERY--VPDVDIWTLETTHRISLFARQWNRSTAQWLKRLVFQRSRRWP-------VLQTFAFSAWWHGLHPGQVFGFLCWSVMVKADYLIHT-FANGCIR-----SWPLRLLYRSLTWAHTQIIIAYVMLAVEGRSFSSLCRLCCSYNSIFPVTYCLLLFLLARRKHKCN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96T53-1", "uniprot_id": "MBOA4_HUMAN", "id": "Q96T53-1", "name": "Membrane-bound ghrelin O-acyltransferase MBOAT4", "aln": "-----------------------MEWLWLFF-LHPISFYQGAAFPFALLFNYLCIMDSFSTRARYLFLLTGGGALAVAAMGSYAVLVFTPAVCAVALLCSLAPQQVHRWTFCFQMSWQTLCHLGLHYTEYYLHEPPSVRFCITLSSLMLLTQRVTSLSLDICEGKVK---AASGGFRSRSSLSEHVC-KALPYFSYLLFFPALLGGSLCSFQRFQARVQG-----------------------SSALHPRHSFWALSWRGLQILGLECLNVAVSRVVDAGAGLTDCQQFECIYVVWTTAGLFKLTYYSHWILDDSLLHAAGFGPELGQ-SPGEEGY--VPDADIWTLERTHRISVFSRKWNQSTARWLRRLVFQHSRAWP-------LLQTFAFSAWWHGLHPGQVFGFVCWAVMVEADYLIHS-FANEFIR-----SWPMRLFYRTLTWAHTQLIIAYIMLAVEVRSLSSLWLLCNSYNSVFPMVYCILLLLLAKRKHKCN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B1Q006-1", "uniprot_id": "MBOA4_DANRE", "id": "B1Q006-1", "name": "Membrane-bound ghrelin O-acyltransferase mboat4", "aln": "----------------------MIDLLWISSDGHPQLFYQFINIPFAFLFHCLSSQGHLSIINRYVYLAMGGFMLAIATMGPYSSLLFLSAIKLLLLIHYIHPMHLHRWILGLQMCWQTCWHLYVQYQIYWLQEAPDSRLLLAISALMLMTQRISSLSLDFQEGTIS---NQS---------------ILIPFLTYSLYFPALLGGPLCSFNAFVQSVER-----------------------QHTSMTSY-LGNLTSKISQVIVLVWIKQLFSELLKSATFNIDSVCLDVLWI-WIFSLTLRLNYYAHWKMSECVNNAAGLGVYFHK-HSGQTSWDELSDGSVLVTEASSRPSVFARKWNQTTVDWLRKIVFNRTSRSP-------LFMTFGFSALWHGLHPGQILGFLIWAVTVQADYKLHR-FSHPKLN-----SLWRKRLYVCVNWAFTQLTVACVVVCVELQSLASVKLLWSSCIAVFPLLSALILIIL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08548-1", "uniprot_id": "ALE1_YEAST", "id": "Q08548-1", "name": "Lysophospholipid acyltransferase", "aln": "-----------MYNPVDAVLTKIITNYGIDSFTLRYAICLLGSFPLNAILKRIPEK-RIGLKCCFIISMSMFYLFGVLNLVSGFRTLFISTMFTYLISRFYRSKFMPHLNFMFVMGHLAINHIHAQFLNEQTQTTVD-----ITSSQMVLAMKLTSFAWSYYDGSCTSESDFKDLTEHQKSRAVRGHPPLLKFLAYAFFYSTLLTGPSFDYADFDSWLNCEMFRDLPESKKPMRRHHPGERRQIPKNGKLALWKVVQGLAWMILSTLGMKHFPVKYVLDKDGFPTRSFIFRIHYLFLLGFIHRFKYYAAWTISEGSCILCGLGYNGYDSKTQKIRWDRVRNIDIWTVETAQNTREMLEAWNMNTNKWLKYSVYLRVTKKGKKPGFRSTLFTFLTSAFWHGTRPGYYLTFATGALYQTCGKIYRRNFRPIFLREDGVTPLPSKKIYDLVGIYAIKLAFGYMVQPFIILDLKPSLMVWGSVYFYVHIIVAFSFFLFRGPYAKQVTEFFKSKQPKEIFIRKQKKLEKDISASSPNLGGILKAKIEHEKGKTAEEEEMNLGIPPIELEKWDNAKEDWEDFCKDYKEWRNKNGLEIEEENLSKAFERFKQEFSNAASGSGERVRKMSFSGYSPKPISKKEE-------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :. . : : . : : : . : :: . .. *::: :::::: . :* : ..:* : :: *. : : :: .: . : .** * : : .*:* . : : : : * : ** * **: : : . ** ** *** ** : * . : : . : * :: .. . . . . : . :::: ", "identical_positions": 26, "similar_positions": 80, "identity": "3.49%" }, { "cls_id": "homologset.agr.SGD:S000005702", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GEM4-1", "uniprot_id": "A0A8I6GEM4_RAT", "id": "A0A8I6GEM4-1", "name": "Ferrochelatase", "aln": "MGPEPRLGEKIRVASKKIKPPLRMGLKPQPTGEGGLQRVSLPEEMLGKPPLPGVVYGSSRACQPWRCQSGP-AVVATTEKAHHAKTTKPQAQPERRKPKTGILMLNMGGPETLGEVQDFLQRLFLDRDLMTLP--IQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKMWTSKQGEGMVKLLDELSPDTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNEVGRKPTMKWSTIDRWPTHPLLIQCFADHILKELDHFPEEKRSEVVILFSAHSLPMSVVNRGDPYPQEVGATVHRVMEQLGYPNPYRLVWQSKVGPVPWLGPQTDEAIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAQKCGAENIRRAESLNGNPLFSKALADLVHSHIQSNKLCSTQLSLSCPLCV-NPVCRKTKSFFTSQQL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22315-1", "uniprot_id": "HEMH_MOUSE", "id": "P22315-1", "name": "Ferrochelatase, mitochondrial", "aln": "----------MLSASANMAAALRA--------AGALLREPL-------------VHGSSRACQPWRCQSGA-AVAATTEKVHHAKTTKPQAQPERRKPKTGILMLNMGGPETLGEVQDFLQRLFLDRDLMTLP--IQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKMWTSKQGEGMVKLLDELSPATAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNEVGQKPTMKWSTIDRWPTHPLLIQCFADHILKELNHFPEEKRSEVVILFSAHSLPMSVVNRGDPYPQEVGATVHKVMEKLGYPNPYRLVWQSKVGPVPWLGPQTDEAIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAQKCGAENIRRAESLNGNPLFSKALADLVHSHIQSNKLCSTQLSLNCPLCV-NPVCRKTKSFFTSQQL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22830-1", "uniprot_id": "HEMH_HUMAN", "id": "P22830-1", "name": "Ferrochelatase, mitochondrial", "aln": "----------MRSLGANMAAALRA--------AGVLLRDPL-------------ASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQVQPQKRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLP--IQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCV-NPVCRETKSFFTSQQL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PIE9-1", "uniprot_id": "A0A8M9PIE9_DANRE", "id": "A0A8M9PIE9-1", "name": "Ferrochelatase", "aln": "----------MAVLGG----------------ACRLVQLVR--------------CGS----PVGLCLSSSLRRQSTATAAAFNTTATPETK-ESRKPKTGILMLNMGGPEKLEDVHDFLLRLFMDTDLMQLP--VQNKLGPFIAKRRTPKIQEQYSKIGGGSPIKAWTTMQGEGMVKLLDEMCPDTAPHKFYIGFRYVHPLTEEAIELMEKDGVERAVAFTQYPQYSCSTTGSSLNAIYRYYSNRADRPKMRWSVIDRWPTHPLLIECFAEHVRNELDKFPVEKRDDVVILFSAHSLPLSVVNRGDPYPQEVGATVQRVMDRLGHCNPYRLVWQSKVGPMAWLGPQTDEVIKGLCQRGKRNLLLVPIAFTSDHIETLHELDIEYSQVLGEEVGVENIRRAESLNGNPLFFRALADLVQSHLQSNESCSRQLTLRCPLCV-NPTCAQTKAFFSSQKL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V9S8-1", "uniprot_id": "HEMH_DROME", "id": "Q9V9S8-1", "name": "Ferrochelatase, mitochondrial", "aln": "-----------------------------------------------------------------MFLHNTKFCRLASGLAGGVRNLS------GQKPKTAILMLNMGGPTHTDQVHDYLLRIMTDRDMIQLP--VQSRLGPWIAQRRTPEVQKKYKEIGGGSPILKWTELQGQLMCEQLDRISPETAPHKHYVGFRYVNPLTENTLAEIEKDKPERVVLFSQYPQYSCATSGSSFNSIFTHYRSNNLPSDIKWSIIDRWGTHPLLIKTFAQRIRDELAKFVETKRNDVVILFTAHSLPLKAVNRGDAYPSEIGASVHMVMQELGQTNPYSLAWQSKVGPLPWLAPATDDAIKGYVKQGLKNFILVPIAFVNEHIETLHELDIEYCDELAKEVGVEEIRRAATPNDHPLFIDALTNVVADHLKSQQAVNPKFLMRCPMCS-NPKCRESKSWYRQLCSN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P16622-1", "uniprot_id": "HEMH_YEAST", "id": "P16622-1", "name": "Ferrochelatase, mitochondrial", "aln": "-------------------------------------------------------------MLSRTIRTQGSFLRRSQLTITRSFSVTFNMQNAQKRSPTGIVLMNMGGPSKVEETYDFLYQLFADNDLIPISAKYQKTIAKYIAKFRTPKIEKQYREIGGGSPIRKWSEYQATEVCKILDKTCPETAPHKPYVAFRYAKPLTAETYKQMLKDGVKKAVAFSQYPHFSYSTTGSSINELWRQIKALDSERSISWSVIDRWPTNEGLIKAFSENITKKLQEFPQPVRDKVVLLFSAHSLPMDVVNTGDAYPAEVAATVYNIMQKLKFKNPYRLVWQSQVGPKPWLGAQTAEIAEFLGPK-VDGLMFIPIAFTSDHIETLHEIDLG---VIGESEYKDKFKRCESLNGNQTFIEGMADLVKSHLQSNQLYSNQLPLDFALGKSNDPVKDLSLVFGNHEST", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ::. *.*:::***** :. *:* ::: * *:: :. *. :. :**: ***:::::* .******* *: *. : : **. .* ***** *:.***.:*** :: : :* ::.: *:***::* :*:***:* :: : ** **** *: **: *::.: .:* .* *..**:**:*****:..** **.** *:.*:* :*:.* *** *.***:*** .**.. * : : : .::::****..:*****:*:*: :.:. ::::*. : *.: * .::::* .*::*:: . :: : .: * . . : . ", "identical_positions": 117, "similar_positions": 131, "identity": "25.55%" }, { "cls_id": "homologset.agr.SGD:S000005704", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LMU7-1", "uniprot_id": "A0ABK0LMU7_RAT", "id": "A0ABK0LMU7-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEASGEQLHRSEASSSTSSEDPPPA----------------------------------EELSVPEVLCVESG-----TSEVPIPD-----------------------------------------DQLQDRLLSAQKVAALPEQEELQEYRR-------------------------------------------------------------------------SRVRSFSLPADPILQAAKLLQQRQQ-----AGQPSSEGGEPAGDCCSKCKKRVQFADSLGLS--------------------------LASVKHFSEAEEP------------------------------------------------------------QVPPAVLSRLHSFPLRAEDLQQLGELLAVAKVP---APLLTPRAQLRPLFQLPGLI----------------------------------------------------------------------------------------------------------------------------------------------AAEERLRRQRVCLERVQCSQPPR----------------------------------------------------------------------------------------------------AEVTGSGRVISCPGPRA------------------------------------------------VAVRYTFTEWRTFLDVPAELHPESLEPLSP-VRSGNSGPGAEDSEGEPGTERFCFSLCLPPG--------------------------------LQPKEGEDADTWGVAIHFAVCYRCEQGEYWDNNEGANYTLRYVCSTDPL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CW07-1", "uniprot_id": "PP13G_MOUSE", "id": "Q9CW07-1", "name": "Protein phosphatase 1 regulatory subunit 3G", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDPSGEQLHRSEASSSTSSGDPQSA----------------------------------EELSVPEVLCVESG-----TSETPIPD-----------------------------------------AQLQDRPLSPQKGAALPEQEELQEYRR-------------------------------------------------------------------------SRARSFSLPADPILQAAKLLQQRQQ-----AGQPSSEGGAPAGDCCSKCKKRVQFADSLGLS--------------------------LASVKHFSEAEEP------------------------------------------------------------QVPPAVLSRLHSFPLRAEDLQQLGGLLAVATMP---DPLLVPCARLRPHFQLPELR----------------------------------------------------------------------------------------------------------------------------------------------AAEERLRRQRVCLERVQCSQPPR----------------------------------------------------------------------------------------------------AEVTGSGRVISCPGPRA------------------------------------------------VAVRYTFTEWRTFLDVPAELDPESVEPLPP-LQSGDSGSKAEDSEEGPGTERFHFSLCLPPG--------------------------------LQPKEGEDAGAWGVAIHFAVCYRCEQGEYWDNNEGANYTLRYVCSTDPL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B7ZBB8-1", "uniprot_id": "PP13G_HUMAN", "id": "B7ZBB8-1", "name": "Protein phosphatase 1 regulatory subunit 3G", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPIGARLS-LEAPGPAPFREAPPA----------------------------------EELPAPVVPCVQGGGDGGGASETPSPD-----------------------------------------AQLGDRPLSPKEEAAPQEQEELLECRRR------------------------------------------------------------------------CRARSFSLPADPILQAAKFLQQQQQQAVALGGEGAEDAQLGPGGCCAKCKKRVQFADTLGLS--------------------------LASVKHFSEAEEP------------------------------------------------------------QVPPAVLSRLRSFPMRAEDLEQLGGLLAAAAVA---APLSAPPSRLRPLFQLPGPS----------------------------------------------------------------------------------------------------------------------------------------------AAAERLQRQRVCLERVQCSTASG----------------------------------------------------------------------------------------------------AEVKGSGRVLSCPGPRA------------------------------------------------VTVRYTFTEWRSFLDVPAELQPEPLEPQQPEAPSGASEPGSGDAKKEPGAECFHFSLCLPPG--------------------------------LQPEDEEDADERGVAVHFAVCYRCAQGEYWDNNAGANYTLRYARPADAL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B9X2-1", "uniprot_id": "A0A8M2B9X2_DANRE", "id": "A0A8M2B9X2-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRMWSCYWVTSPHTHLLI----------------------------------QRGSPGVTLAVIGDYR---TEMMSIMN-----------------------------------------AEQMENGLDSDDDLQPEEIPEYLKDRR----------------------------------------------------------------------------RAKSLPAYPEQASLYHQISQN------------------------CRKRVKFADALGLN--------------------------LASVKHFSTSEDP------------------------------------------------------------QIPAKVFNRLKSFPLQKE-----REFIDDLCVN---IRSSLALDYLVPTFKTPVDSG---------------------------------------------------------------------------------------------------------------------------------------------DQETRLARGRVALESVTVTQ-------------------------------------------------------------------------------------------------------FDVRG---IIRATGGRE------------------------------------------------VGVRYTFNDWLSFVDAQAIP------------------------VATEDTTRYSFTMYTPPF--------------------------------LDP---------SASVHFAVYMKDDNSEFWDNNDGLNYSLKYHSSSPSETAAFHAV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9JIG4-1", "uniprot_id": "PPR3F_MOUSE", "id": "Q9JIG4-1", "name": "Protein phosphatase 1 regulatory subunit 3F", "aln": "-----------------------------------------------------------------------------MARTAPVEPPLRHPAPPSPAAGEPR--ASAEAAVAPRRVLFADEALGLPLAQLRRYRPWGGPGAGKMAAATGQDGGGGG-ADEEDDGEDGDEGEEEEEAFPDPSPPCPVPAGGGFYLVPTFSLPPALGRLERLGRVMVELEALLPPP----------------------------------GAVPGGSGVWVPGGRPPVVRGLVRVLNRSFEKAVHVRASHDGWATFCDHPARYVPRSPPGAGVG---GTGAGDPLLDPGLGLGPGQMSASSPDDGGCTDRFAFQLPFAEGASDGARLDFVVRYETPEGTFWANNHGRNY----------------------------TVLLRIAPAPTPTDAEGLPQQQQLQQLEPQPECQGPVEAEARQLKSCMKPVRRRPFEEEPRMRSADDN--------------------TLAEHPDVRESLGP------------------------------------------------------------LLAPTPLRPWPQMTLQVPEVMLTSNPQEEGDIPRSNPPVAFTEVRQAPAIRILPAT--CGLGGPPRDQASGPDASDRAAGSFLEPTQQQVEAAWESGGGRKAPMVGALTDEPARGLEIVSGLDELLGEDTIDQELEQLYLSHLSRLRAVAAAG----GGEG-----TSPTHALGILTDRDLILKWPGPERALNSALAEEITLHYARLGCGVELIKDTEDPD----------------------------------------------------------------------------------------------------DEGEGEDGLSITPSSPEGGSPKESP--------------------------------PEILSGARSVIATMGDVWVPWAERSSSRCDSPVVLGTQGQFTENPEKGMGKDTKSLHLNRVIVGMSKSPGEAGTESQMEELPTERESSWVPSSEKELPLPVQQE-QSPALLGPTGTEVCLSSVAKPHVNSQEEEGGSLNLESPKRSPMPAAPAECACGLAPQLWGPLTQTLGVLAGLVMVPVALNSGVSLLVLVLCLSLAWFS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZSY5-1", "uniprot_id": "PPR3F_HUMAN", "id": "Q6ZSY5-1", "name": "Protein phosphatase 1 regulatory subunit 3F", "aln": "-----------------------------------------------------------------------------MARTAPVEPPLRHSAPPSPAAGEPR--TSVEAAVAPRRVLFADEALGLPLAQLRRYRPWGGPGAGKMAAAAGQDGGGGGGADEDDDGEDGDEGEEEEEACPEPSPLCPVPAGGGFYLVPTFSLPPAPGRLERLGRVMVELEALLPPP----------------------------------GAVPGGAGVWVPGGRPPVLRGLVRVLNRSFEKAVHVRASHDGWASFCDHPARYVPRSPPWAGAG---GTGAGDPILDPGLGLGPGQASASSPDDGGRTDRFAFQLPFAEGAGDGARLDFVVRYETPEGTFWANNHGRNY----------------------------TVLLRIAPAPTPTDAEGLPQQQQLPQLEPQPECQGPVEAEARQLKSCMKPVRRRPAEEELKTKNMDDNTF------------------AMAEHPDVQESVGP------------------------------------------------------------LVAPTPLRPWPQMTLQVSDVPMTGNPAEEGDVPRSSPPVAFTEVLQAPAIRIPPSSPLCGLGGSPRDQASGPDASEGATGPFLEPSQQQAEATWG------------VSSENGGGLEAVSGSEELLGEDTIDQELEQLYLSHLSRLRAAVAAGGAGGGGEGSTDGGMSPSHPLGILTDRDLILKWPGPERALNSALAEEITLHYARLGRGVELIKDTEDPD----------------------------------------------------------------------------------------------------DEGEGEEGLSVTPSSPEGDSPKESP--------------------------------PEILSGARSVVATMGDVWLPWAE--GSGCDGPVVLGTEGQFIGDPEKGMGKDTSSLHMNRVIAGVTESLGEAGTEAQIEVT-SEWAGSLDPISGKEPASPVLLQGQNPTLLSPLGAEVCLSSVARPHVSSQDEKDAGPSLEPPKKSPTLAVPAECVCALPPQLRGPLTQTLGVLAGLVVVPVALNSGVSLLVLALCLSLAWFS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NFA7-1", "uniprot_id": "A0A8M1NFA7_DANRE", "id": "A0A8M1NFA7-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAWSLGCCHKVTPL----------------------------------EEMNVDLFFTTVSDGSK--ETSTSILQ------------------------------------------DMSRSKTDSERRLVKIRPPSPRTTPR--------------------------------------------------------------------------QTAGRSLSCEPPTKSIIQRRTQSLP-------------SPSERRRLSRRANVRFVDSLGLD--------------------------LKNVKVFKSGEDP------------------------------------------------------------FIPEHVLFRLLMNAELASS-----------------KRMEISLPYLKPLFSIQPGDS--------------------------------------------------------------------------------------------------------------------------------------------SDFVERLCFQQVCLERVLCYEP-------------------------------------------------------------------------------------------------------GIIGIVQVVNLAFEKE------------------------------------------------VSVRYSFTNWKSCSETKAYWVASKFN------------------SNGPCCDTFRFHLPVPPF----------------------------------------ILHPGAVLEFAICYKVMGTQFWDNNGGQNYKLTCQSYNLPVPKECEDSMIHFI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BRJ4-1", "uniprot_id": "PPR3E_MOUSE", "id": "Q8BRJ4-1", "name": "Protein phosphatase 1 regulatory subunit 3E", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPERPPR----------------------------------TDIPRNLSFIAALTERAYYRSQRPSLE-----------------------------------------EESEEEPGEGGTRPGARSRAHVPGRGR----------------------------------------------------------------------------RARSAPAGGGGARTARSRSPD------------------------TRKRVRFADALGLE--------------------------LAVVRRFRPGEPP------------------------------------------------------------RVPRHVQVQLQRDALRHFAP---------------CPPRARGLQEARVALEPALEPG----------------------------------------------------------------------------------------------------------------------------------------------FAARLQAQRICLERADAGP-------------------------------------------------------------------------------------------------------LGVAGSARVLDLAYEKR------------------------------------------------VSVRWSADGWRSLRESPASYAG--------------------PAPSPPRADRFAFRLPAPPV--------------------------------------------GGTLLFALRYRVTGREFWDNNGGRDYALLGPEHPAGAGAAEPQGWIHFI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B5E2-1", "uniprot_id": "A0ACD6B5E2_DANRE", "id": "A0ACD6B5E2-1", "name": "", "aln": "MESVGALGSPIGGSSNSLSLPASPWEEDEESLGLEGIKPKSSPTPRRRSSASSDDSLPPPSSSRRVSFADAFGLSLVSVKQFDAWGATPPSGPLESDLNEDK--EYYMVPLFTLPQTSEELELRVHEQKLELESLELLSGTTTLRGIVRVLNVCFDKMVYVRTSLDSWRSHFDLLAEYSSGSNNGEMDCFSFKLTLVPPFGEEGARVDFCLRYETSVGTFWANN----------------------------------SEKNYSLLCCEKLKEKGQSESENRRKSCLKITSTNSSASTSTTTNNEKLPVVNLNDVKATDPES---VSENSEKSEKESKELAEEMSRNRSRRNRRKAARLQKVKEHFAKREEEQKRGTKTK-ESEVTAETSTLRLEMT----------------------------TCSSLSQQTPQPPTDTQISSSPAESLKSTDDIGDSKDICCIDNIINFSKAQTNLPLGDSISCDETVTSSASEVLKD--VPLKDNVTDQKVSNSQSFPECQNSDLSISKDVER---------------------------------------------AWEHFEKDAKQRIKHLALSLKVDEDVNVAGGNREDNVSLKTANTETQLFSQGFTFRTIVAPLYHQVFKNMEIEKKDFTPKILQVNRSFKELKNKSLTAVTTP------------ETFISLQREVHNISVDDCKASTDQNKTVNPTKSPLSESNKSECVEDSHNQNDPSGYPTDIIFIEANLPKVTSSQLDPSLEECKDETFQYDYCHSLFPLQAAEHFVNTNQATE----------------------------------------------------------------------------------------------------SDIDNLSEQIHPSAATSALKTLLSLN-------------------------------TEMSQNQEDPTNIRTKEEDTLVQTENSIINSCILAKSPDDPTTRQTSGINLEPDKLEPDCCKISYIEKPEDLCDLSNATAVLTEQCSKLDN--------TEIIMCNTMQTCNMNGKKAEFSSKTTEKECSNIIDFEGEQITLANKEVEDGSETTNSESLEEEEEGTRKGEKEKDQDPEEHEGEKDKQENKGGLKSIEDELKYIDDEEDLDEMKPERENKQVDADYLVSLERDSEDQKRFNSTCNVQSVTQRNIDLNECLCGVEVLENQESFISGVQICEETGTSWQESSQKSDTEVSGSTIALENSWDAGDQEMKVFCESKTMADYKNMEYEAKDSLSGDSGNTEDNTSTESQIDEEMELYLNSLRNSQQSAFREGTMSGSKRPSISRRRPSMP---------SISESVDEDHQNSSLEDLSNIALLTESKRAMLPLVDRNERVIGRNVLWWKKFLSYDNMKRMIGYTFLLIVFLVLAYHYDFIACFALYLLTVYWLFHQGEGEPLKKSQNCEKRLQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58J961-1", "uniprot_id": "A0AC58J961_DANRE", "id": "A0AC58J961-1", "name": "", "aln": "---------------MSVEETTCNLEPPNCKDWIMKNQEDKMEQVAEDESEEEEPEPPLIALRRKVSFADAFGLDLVSVKEYDNR-----------DSSEGG--EYYISCLFTIADLILDMEAKLQQQKLELERFELLPGSTTIRGIVRVLNLCFHKSVYVRVTLDGWQSHFELMAEYVPGSSDGQTDCFCFHLNLMPPFPVEGLRVEFCLRYESAVGTFWASNGGTNYIMFCYQRRRSNFKEHPRENEKEIEKEKVEEGLHKGIRSCLKANSKNYTEATAAEASGGIPGEFLMWRSGCKESDDKILSLIVYFTEQATAKVGRNRNKTEEEAGITSCKSLKDCCKTLVDRRRKRQAARLAHVQSYFAQKATETQMGCNSITDESSTSIPRLSIQSRTDNQQGFGMDTPPILMYHQIPLLSLDWGSTSTTPPQVNPPNTESQQVEDHQAELSFDAFLKGSDTAIPHSDMQDQACASPESLDHSEVSASRDRVGGLEDREAWKNYSQESAKRRTTNIIQSDATQQGKDPITSLSSDQVVNYQLVKEPMVTTLPWSVLDSRDQIVVPMEDRGAEKDYSQGTDDRGAIETIKSDPTVQVKDLSTSLSSDQVVDYQLAKEPSITTVPCSVLPSRDQIVVPMEDREAEKGYIQGSADRRAIETIKSDPTEQGKNLSTGLSSDQVVEDYQLAKEPSVTAIPCSVLASRDKNMIPIEDRGAKKDNSQWSDDKRAIESIKSDPTDQRKDLSLSLSSYEVVDHQLVKEPSVTIVPCSVLASREQIEVPMEDREAEKKCSQWSADRGAIEIITSDPTEQGKQPSTSLSSDQVVEDYQLVKEPSVTAIPCSFLASRDKNVVPIEDGGAEKGYILGSGDRRAIEIIKSDPTEQGKDLITRLSNDQIMNYHLGEEPSATTVPCSVLASGDQIEVPMVNKGDEKKYSQWSADRRAIETIKSDPTEQGKDRSTILSSDQVVVDCQLVKEPSVTAIPCSFLALRNKNVPIEDSGAENGYIQGSGDRRAIEIIKSDPTEKGKNLSTSLTRDQDVDYRLVKESKATTVPCFALASRDQIEVPVEELEAVKNDSQWSADRMAIEVIKSEPTEQGKDLSTGLSSDRVVDYQLVKEPRVTTVPCSVLGSEPDRLERELEASRDCQTPHHELTSGFLSQDTTKASPGDETGIAHDTETQNSEAGDGISPEECTGSSDTSKVKENTHRAVKDILTFTGIRDVPLTNRQAEGSSPKRKVINIDDSEEQVEMRWFYTELHEEDAESSRKGQDETTMDHSAEIQSVSSCASEAFNENELCTMNKNLHKDNSELQKSEERRFEANEGLKIKEQLNETTIEAAKGGEEDEMCSESKRELIEDSRAIGDNCTDEDLTSKVTYLTDSTDLPKHIPQTTSIKDREVNSQDEEFELGKSLNGSSNRLFSWWQEFNSLGHMAKALLYAILFVIFITTYLCDMPTCLALYLFSLCWWCSQGMKQRLDGASVDVD---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZM60-1", "uniprot_id": "D3ZM60_RAT", "id": "D3ZM60-1", "name": "Protein phosphatase 1 regulatory subunit 3A", "aln": "MEPAEVPGQISKDNFLEVPNLSDSVCEDEEVKATFKPGFSPQPSRRGSESSEDLYLDTPTSASRRVSFADSLGFSLVSVKEFDCWDLPSVSTDFDLTRDVLHTDEYILSPLFDLPSSKEELMEQLQVQKAVLESAEHLPGSTSVKGIIRVLNISFEKLVYVRMSLDDWQTHYDILAEYVPNSCDGETDQFSFKISLVPPYQMDGGKVEFCIRYETSVGTFWSNN----------------------------------NGTNYILVCQKKTKEPEPVVKPLEEGPSRQIKGCLKVKSSSKEEPLLTPEENKLGTLKFTESYIPTIICSHEDRDDLGANYQHVKDIDKKHDEHNEKELDLMINQRLITSHDEKN----------------------------------------------------TFSTDAVNSTNKAEGSEKKQARHEIHTDLCRGPLSPSLSAESSLKRDFYHSRNYSPGNEHGHPPSEEIISDVGAIG---SPLGDTSSDELMQLKVCSKEDVDDN----------------------------------------------------------ANPAHGSGRLCSSSDQLRAGGLENNEAGIKKTGIKDYKYSHGDSYLEASTSLRESNASYKDEYDKVDDKREKKTCLGVNENPGKNFQSIFQNQERQMG-----------------------------------------------------------CAKISGEGANANNQDLTTLLSKDTTTNTWAVTVDPSPSTNTNVNWREAGNGTDLERRTTDLGSPRN--------------------------------------------------------------------------------------------------FSLLTDGYLFQADREKSDSSNSEDR----------------------------------------NMNPQHKKNWNVLESQPETRETETNITKHTKEQAEYKDTWGKRDNSRNLKATSTEQLFTCQETECCELSS------------------------LADHGITEKAQAVAAYIIKTTLESTPESASARGKAIIAKLPQETARHDRPIEVKETAFDPHEGRKDDSHYSLCHGDTAGVIHDNDFERESHLDICNVRVDEMEKEKTTSTCSPRKTYDKEKHGIGSVTSIDEPSQVITGNQKATSKLDLHLGVLPTDRAILSANADLELLQELSRRTDFNAVHSAFNSDPGSASQDSSQVYRR------------CSKKPVPSYGEQKAVINTTLQSVPTKSEYNCHPESEIFGHATSKPEVVFKSSEIIKSGSGGEQGVGPILQQKEGSLEKSQDPMISINEPLENLDEVRSENEGLMRSGQLQCYLGDKGSVSSASATVPTQELQAQGSESLLSISINSKIPYFLLFLIFLATVYYYDLMIGLAFYLFSLYWLYWEGGRQRESVKKK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28006-1", "uniprot_id": "GAC1_YEAST", "id": "P28006-1", "name": "Serine/threonine-protein phosphatase 1 regulatory subunit GAC1", "aln": "--------------------------------------------------------------------------------MVIQTATTLSPAKARPSFPHNDLIKSMSDSLISRPTHPPIRKLKSSLKISHPEPISRSKSEIFCTSPEKNVRFAIELTTVKRFDKNAEPSSISNENSPTLSPVDSNTAADDVQLFNNEDCWFNDSSLVTNLLKNEKKFRYMNSLN---------------------------------NMFKLDLYDSEDEDDIDEHINSQAEYG--------------------------------------YTYNSLSTRGKTSENKSATSSLATQATNICDWKLH-------------------------------------------------------------------CTDLVPFKIAPPLFTKTLSASDLQGQLTKYLNGQNVKLHSLTQLGDDSSKITGLVYVKNLSFEKYLEIKFTFN---------------SWRDIHYVTANFNR------------------------------------------------------------TINSNVDEFKFTIDLNSLKYILLIKRIITMEKNTSSCPLNIELCCRYDVNNETYYDN---------------------------------------------------------------------------------------------------------------------------------------------NNGKNYHLFMTTFKKGGETKEKIP----------------------------------------------------------------------------------------------------VVVEPASQTDAAMSPKEMKAR------------------------------------------FVSSNPTLSRFLPQSRKFSEDTDYYNTSPLKHLYHNDTTSWVKPKRLNVVLDKLENATPPPPSS------------------------------ALANDTARTGKITKDKNNVLAPPTASNSIDLPILGSQHQSLYSGSSSYSSSSSSISSSLSFASSNNSSTNSSSASCSFPLTELDNFDYANLYEPNDTFTTANLFNHSLNSLMPEISTPSFFGGFRNENTINNNDSKNLVTSLEDSYEDKQSVITDTTMDENNKTSTINNSTDTLIKPSKENGTVKENKSSANSTSAPSS----------------------SQNRASTILNDHSNGKSDLKYVNYQSLLDSHCFYNHPSSPNLQSTSFSSAAPFSGISQASDIFDYENEDSDSNQIAGEIDNNSFPPHFYLDEDDKSACLSDDALIDHHRNTNPFINTFSSSPPILSQEVDRWRL-------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "D3ZSF0-1", "uniprot_id": "D3ZSF0_RAT", "id": "D3ZSF0-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLEGRLPSVSLLSVFFCFQFRWLFSFSEDKGNK-----------------------------------EVTSPAVIIRQQIEQEDSEHCREEGR-----------------------------------------AAAKGCSINAGSSWNQVQPLKISSGKRP------------------------------------------------------------------------SELQGPRVSSQPRSSLLGISQPAADKLVETIPREGRQEQAELSSRYQAASGGRLFLDFHSMEIIKGGADEDS-------------ASDLSDSERVAIPPSP------------------------------------------------------------FTPPDLNLRAEEIDPVSFSLHPEPSQAESGHCYPDFLPPPFNSWDLRDMAVVLNTECRTEALPRATG-------------------------------------------------------------------------------------------------------------------------------LLGKYIDRLLQLEWLQVQTVQGEKARAAK--------------------------------------------------------------------------------------------------AKLPGAAGGLKSPGRGK------------------------------------------------LLTSSLSKPLPSPEGISKPGPSRKKGFRHEEAHPSYYAFETLPNSGDGPGRPRLCSQKQAPE---------------------------------PRMEKKKKSSKGPKPQLRAPPCVEGNPAMEANGNIRIPKQSPVLLDPVGSYRASRTQAHVDLKKKGSANNCGCAPSSGEKKLKTNGAKQSTYKLK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . ", "identical_positions": 0, "similar_positions": 4, "identity": "0.0%" }, { "cls_id": "homologset.agr.SGD:S000005706", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GEJ2-1", "uniprot_id": "A0A8I6GEJ2_RAT", "id": "A0A8I6GEJ2-1", "name": "Chromodomain Y-like protein 2", "aln": "-------------------------------------------------------MASGDLYEVERIVDKRKNKKGKWEYLIRWKGYGSTEDTWEPEHHLLHCEEFIDEFNGLHLPKDKK--------------VKSGKQAGASKLLRDARSLPVERLSHRPLEPGKSKSTSHKRKRVNSPLSRSKKGSSGKAP---DRATKTVSYRTTPSGLQIMPLKKAQ---NGLENGDAGSEKDESHFGNGSHQPDLELN--------DQLGEQETSDCDGTHSALVENG-------IGSALTNGGLNLHSPVKRK-------LETEKDYVFDKRLRYSVRQNESNCRFRDIVVRKEEGFTHILLSSQTSDNNALTPEIMKEVRRALCNAATDD-SKLLLLSAVGSVFCSGLDYSYLIGRLSSDRRKESTRIAEAIRDFVK-------AFIQFKKPIVVAINGPALGLGASILPLCDIVWAS-EKAWFQTPYATIRLTPAGCSSYTFPQILGVALANEMLFCGRKLTAQEACSRGLVS--QVFWPTTFSQEVMLRVKEMAS-CSAVVLEDSKCLVRSFLKSVLEDVNEKECLMLKQLWSSSKGLDSLFSYLQDKIYEV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D5D8-1", "uniprot_id": "CDYL2_MOUSE", "id": "Q9D5D8-1", "name": "Chromodomain Y-like protein 2", "aln": "-------------------------------------------------------MASGDLYEVERIVDKRKNKKGKWEYLIRWKGYGSTEDTWEPEHHLLHCEEFIDEFNGLHLSKDKR--------------VKSGKQAGASKLLRDARGLPVERLSHRPLEPGKSKPSSHKRKRVNSPLSRPKKGSSGKAP---DRATKTVSYRTTPSGLQIMPLKKAQ---NGLENGDAGSEKDESHFGNGSHQPDLELN--------DQLGEQEASDCDGTHSALVENG-------VGSALTNGGLNLHSPVKRK-------LETEKDYVFDKRLRYSVRQNESNCRFRDIVVRKEEGFTHILLSSQTSDNNALTPEIMKEVRRALCNAATDD-SKLLLLSAVGSVFCSGLDYSYLIGRLSSDRRKESTRIAEAIRDFVK-------AFIQFKKPIVVAINGPALGLGASILPLCDIVWAS-EKAWFQTPYATIRLTPAGCSSYTFPQILGVALANEMLFCGRKLTAQEACSRGLVS--QVFWPTTFSQEVMLRVKEMAS-CSAVVLEESKCLVRSFLKSVLEEVNEKECVMLKQLWSSSKGLDSLFSYLQDKIYEV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N8U2-1", "uniprot_id": "CDYL2_HUMAN", "id": "Q8N8U2-1", "name": "Chromodomain Y-like protein 2", "aln": "-------------------------------------------------------MASGDLYEVERIVDKRKNKKGKWEYLIRWKGYGSTEDTWEPEHHLLHCEEFIDEFNGLHMSKDKR--------------IKSGKQSSTSKLLRDSRGPSVEKLSHRPSDPGKSKGTSHKRKRINPPLAKPKKGYSGKPSSGGDRATKTVSYRTTPSGLQIMPLKKSQ---NGMENGDAGSEKDERHFGNGSHQPGLDLN--------DHVGEQDMGECDVNHATLAENG-------LGSALTNGGLNLHSPVKRK-------LEAEKDYVFDKRLRYSVRQNESNCRFRDIVVRKEEGFTHILLSSQTSDNNALTPEIMKEVRRALCNAATDD-SKLLLLSAVGSVFCSGLDYSYLIGRLSSDRRKESTRIAEAIRDFVK-------AFIQFKKPIVVAINGPALGLGASILPLCDIVWAS-EKAWFQTPYATIRLTPAGCSSYTFPQILGVALANEMLFCGRKLTAQEACSRGLVS--QVFWPTTFSQEVMLRVKEMAS-CSAVVLEESKCLVRSFLKSVLEDVNEKECLMLKQLWSSSKGLDSLFSYLQDKIYEV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WTK2-1", "uniprot_id": "CDYL_MOUSE", "id": "Q9WTK2-1", "name": "Chromodomain Y-like protein", "aln": "MGIGNSQPNSQEAQLCTLPEKAEQPTDDNTCQQNNVVP------ATVSEPDQASPAIQDAETQVESIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFNRRHNERQKEGSLARASRASPSNARKQISRSTHSTLSKTNSKALVVGKDHESKSSQLLAASQKFRKNPAPSLANRKNMDLAKSGIKILVPKSPVKGRTSVDGFQGESPEKLDPVDQGAEDTVAPEVTAEKPTGALLG-PGAERARMGSRPRIHPLVPQVSGPVTAAMATGLAVNGKGTSPFMDALAANGTVTIQTSVTGVTAGKRKFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMKEVQSALSTAAADD-SKLVLLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMADAIRNFVN-------TFIQFKKPIIVAVNGPAIGLGASILPLCDVVWAN-EKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLFSGRKLTAQEACGKGLVS--QVFWPGTFTQEVMVRIKELAS-CNPVVLEESKALVRCNMKMELEQANERECEVLKKIWGSAQGMDSMLKYLQRKIDEF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYK9-1", "uniprot_id": "CDYL_RAT", "id": "Q6AYK9-1", "name": "Chromodomain Y-like protein", "aln": "MGLGSSQPSTKEAEPCTLQEKEEHPVDD-TRQQNNAVP------ATVSDPDQVSPAVQDAETQVESIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFNRRHNERQKEGTLARANRASPSNARKQISRSTHSALSKTNPKALVVGKDHESKTNQLLATSQKFRKNTAPSLANRKNMDLAKSGIKILVPKSPIKGRTSIDGFHGESPEKLD---QGAEDTVTPEVTAEKPTGALLG-PGAERARMGSRPRIHSLVPQVSGPVTAAMATTLAVNGKGTSPFMDALTANGTVTIQTSVTGVTAGKRKFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMKEVQSALSTAAADD-SKLVLLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMAEAIRNFVN-------TFIQFKKPIIVAVNGPAIGLGASILPLCDVVWAN-EKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLLSGRKLTAQEACGKGLVS--QVFWPGTFTQEVMVRIKELAS-CNPIVLEESKALVRCNMKMELEQANERECDALKKIWGSAQGMDSMLKYLQRKIDEF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y232-1", "uniprot_id": "CDYL_HUMAN", "id": "Q9Y232-1", "name": "Chromodomain Y-like protein", "aln": "MTFQASHR-SAWGKSRKKNWQYEGPTQKLFLKRNNVSAPDGPSDPSISVSSEQSGAQQPPALQVERIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFNRRHTEKQKESTLTRTNRTSPNNARKQISRSTNSNFSKTSPKALVIGKDHESKNSQLFAASQKFRKNTAPSLSSRKNMDLAKSGIKILVPKSPVKSRTAVDGFQSESPEKLDPVEQGQEDTVAPEVAAEKPVGALLG-PGAERARMGSRPRIHPLVPQVPGPVTAAMATGLAVNGKGTSPFMDALTANGTTNIQTSVTGVTASKRKFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMREVQSALSTAAADD-SKLVLLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMAEAIRNFVN-------TFIQFKKPIIVAVNGPAIGLGASILPLCDVVWAN-EKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLLSGRKLTAQEACGKGLVS--QVFWPGTFTQEVMVRIKELAS-CNPVVLEESKALVRCNMKMELEQANERECEVLKKIWGSAQGMDSMLKYLQRKIDEF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y6F8-1", "uniprot_id": "CDY1_HUMAN", "id": "Q9Y6F8-1", "name": "Testis-specific chromodomain protein Y 1", "aln": "--------------------------------------------------------MASQEFEVEAIVDKRQDKNGNTQYLVRWKGYDKQDDTWEPEQHLMNCEKCVHDFNRRQTEKQKKLTWTTTSRIFSNNARRRTSRSTKANYSKNSPKTPVTDKHHRSKNRKLFAASKNVRRKAASILSDTKNMEIINSTIETLAPDSPFDHK-TVSGFQK--LEKLDPIAADQQDTVVFKVTEGKLLRDPLSRPGAEQTGIQNKTQIHPLMSQMSGSVTASMATGSATR-KGIVVLIDPLAANGTTDMHTSVPRVKGGQRNITDDSRDQPFIKKMHFTIRLTESASTYRDIVVKKEDGFTQIVLSTRSTEKNALNTEVIKEIVNALNSAAADD-SKLVLFSAAGSVFCCGLDFGYFVKHLRNNRNTASLEMVDTIKNFVN-------TFIQFKKPIVVSVNGPAIGLGASILPLCDLVWAN-EKAWFQTPYTTFGQSPDGCSSITFPKMMGKASANEMLIAGRKLTAREACAKGLVS--QVFLTGTFTQEVMIQIKELAS-YNPIVLEECKALVRCNIKLELEQANERECEVLRKIWSSAQGIESMLKYVENKIDEF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y6F7-1", "uniprot_id": "CDY2_HUMAN", "id": "Q9Y6F7-1", "name": "Testis-specific chromodomain protein Y 2", "aln": "--------------------------------------------------------MASQEFEVEAIVDKRQDKNGNTQYLVRWKGYDKQDDTWEPEQHLMNCEKCVHDFNRRQTEKQKKLTWTTTSRIFSNNARRRTSRSTKANYSKNSPKTPVTDKHHRSKNCKLFAASKNVRRKAASTLSDTKNMEIINSTIETLAPDSPFDHKKTVSGFQK--LEKLDPIAADQQDTVVFKVTEGKLLRDPLSHPGAEQTGIQNKTQMHPLMSQMSGSVTASMATGSATR-KGIVVLIDPLAANGTTDMHTSVPRVKGGQRNITDDSRGQPFIKKMHFTIRLTESAITYRDIVVKKEDGFTQIVLSTRSTEKNALNTEVIKEMVNALNSAAADD-SKLVLFSAAGSVFCCGLDFGYFVRHLRNDRNTASLEMVDTIKNFVN-------TFIQFKKPIVVSVNGPAIGLGASILPLCDLVWAN-EKAWFQTPYTTFGQSPDGCSSITFPKMMGKASANEMLIAGRKLTAREACAKGLVS--QVFLTGTFTQEVMIQIKELAS-YNAIVLEECKALVRCNIKLELEQANERECEVLRKIWSSAQGIESMLKYVENKIDEF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XIC0-1", "uniprot_id": "ECI2_RAT", "id": "Q5XIC0-1", "name": "Enoyl-CoA delta isomerase 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------MAAVTWSRARCWCPSLLQVLRLPVTKLHLGRPAMRATQQDFENAMNQVKLLKKDPGNEVKLRLYALYKQATEGPCTMPKPGVFDFVNKAKWDAWNALGSLPKETARQNYVD--------------------------------------------------------------------------LVSSLSSSSEASSQGKGGADGKAQESKGILVTSEGGITKITFN-RPSKKNAITFQMYQDIILALKNASTDD-TVITVFTGAGDYYSSGNDLTNFTSAS-GGMEEAANKGAIVLREFVN-------TFIDFPKPLVAVVNGPAVGISVTLLGLFDAVYAS-DRATFHTPFSHLGQSPEACSSYTFPKMMGSAKAAEMLLFGKKLTAREAWAQGLVT--EVFPESTFETEVWTRLKTYAK-LPPNSMRISKELIRKNEKEKLHAVNEEECTTLRARWLSEECINAIMSFVTRKPKL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUR2-1", "uniprot_id": "ECI2_MOUSE", "id": "Q9WUR2-1", "name": "Enoyl-CoA delta isomerase 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------MAAVTWSRARCWCPSVLQVFRLQVAKLHLGRPTMRASQQDFENALNQVKLLKKDPGNEVKLRLYALYKQATEGPCNMPKPGMLDFVNKAKWDAWNALGSLPKETARQNYVD--------------------------------------------------------------------------LVSSLSSSSEAPSQGKRGADEKARESKDILVTSEDGITKITFN-RPTKKNAISFQMYRDIILALKNASTDN-TVMAVFTGTGDYYCSGNDLTNFTSAT-GGIEEAASNGAVLLRDFVN-------SFIDFPKPLVAVVNGPAVGISVTLLGLFDAVFAS-DRATFHTPFSQLGQSPEACSSYTFPKMMGSAKAAEMLLFGKKLTAREAWAQGLVT--EVFPESTFETEVWTRLKTYAK-LPPNAMRISKELIRKNEKEKLYAVNAEECTTLQARWLSEECMNAIMSFVSRKPKL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q78JN3-1", "uniprot_id": "ECI3_MOUSE", "id": "Q78JN3-1", "name": "Enoyl-CoA delta isomerase 3, peroxisomal", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPKPGVFNFVNKATWDARNALGSLPKETARKNYVD--------------------------------------------------------------------------LVSSLSSSSEAPSQGKRGADEKARESKDILVTSEDGITKITFN-RPTKKNAISFQMYLDIMHALKNASTDN-SVITVFTGTGDYYSSGNDLKNLINDA-GEIQDVVATSTKILREFVN-------CFIDFPKPLVAVVNGPAVGIAVTILALFDAVFAS-DRATFHTPFSQLSQIPEACSTYMFPKIMGPTKAAEMLLFGKKLTAREAWAQGLVT--EVFPESTFETEVWTRLKTYSK-LSPNVMRISKELIRKHEKQKLYTVNAEECAAALERMPREEYAKALRNFLFRKAKAKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75521-1", "uniprot_id": "ECI2_HUMAN", "id": "O75521-1", "name": "Enoyl-CoA delta isomerase 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------MAMAYLAWRLARRSCPSSLQVTSFPVVQLHMNRTAMRASQKDFENSMNQVKLLKKDPGNEVKLKLYALYKQATEGPCNMPKPGVFDLINKAKWDAWNALGSLPKEAARQNYVD--------------------------------------------------------------------------LVSSLSPSLESSSQVEPGTDRKSTGFETLVVTSEDGITKIMFN-RPKKKNAINTEMYHEIMRALKAASKDD-SIITVLTGNGDYYSSGNDLTNFTDIPPGGVEEKAKNNAVLLREFVG-------CFIDFPKPLIAVVNGPAVGISVTLLGLFDAVYAS-DRATFHTPFSHLGQSPEGCSSYTFPKIMSPAKATEMLIFGKKLTAGEACAQGLVT--EVFPDSTFQKEVWTRLKAFAK-LPPNALRISKEVIRKREREKLHAVNAEECNVLQGRWLSDECTNAVVNFLSRKSKL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P5U3-1", "uniprot_id": "A0A8M9P5U3_DANRE", "id": "A0A8M9P5U3-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MGASVEDFNKAKDKLNTLKKDPGNEVKLKIYALFKQATVGPCNTPKPGMLDFVNKVKWDAWKGLGSISQEDARQQYVD--------------------------------------------------------------------------LISSLVG-AEAPAVAAQPTGG-GKTFQTLLVSTEDNITTIRLN-RPDKKNAITVEMYNELIEALELAGKDD-SVITVMTGNGDYYCSGNDLNNFTKIPEGGVEKMAKDAGELLRRYVK-------AYIDFPKPLIGVINGPAVGVSVTLLGLFDVVYAT-EKATFHTPFSQLGQSPEGCSSYLFPKMMGAAKASEVLLFNKKLSATQACELGLVS--EVFPESSFQSEVWSRLKAYAK-LPKNSLALSKQLIRGLEKEKLHAVNDAEVERLTERWLSDECMQAIMSFFQGKSKL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0M0-1", "uniprot_id": "Q9W0M0_DROME", "id": "Q9W0M0-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTYQG----------YKELLVEQQGKLLVAKFN-NPKKKNCINRVAYQEMTRVLTEVNDDEGVTIVVFTGVGDIFTSGNDLSQSSNTD--DIDAFFKQSNATFKAMVL-------SFVNCRKIVLALVNGPAIGIGATIVGLCDVAWCS-ETTYFYTPFTKLGLVPEGGSSYMLPLILGRSKASEILLLSEPLSAQEAYQFNFVS--RIFKASELESVIWPKLRQYSE-LPTNSLLQGKRLVKDGFLENLIKANEAECKQLLQQFQHPEFAQAIIDFASRKNKAKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08558-1", "uniprot_id": "DCI1_YEAST", "id": "Q08558-1", "name": "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSRVCYHINGPFFIIKLIDPKHLNSLTFEDFVYIALLLHKANDIDSVLFTVLQSSGKYFSSGGKFSAVNKLNDGDVTSEVEKVSKLVSAISSPNIFVANAFAIHKKVLVCCLNGPAIGLSASLVALCDIVYSQNDSVFLLFPFSNLGFVAEVGTSVTLTQKLGINSANEHMIFSTPVLFKELIGTIITKNYQLTNTETFNEKVLQDIKQNLEGLYPKSVLGMKELLHSEMKQKLIKAQAMETNGTLPFWASGEPFKRFKQLQEGNRRHKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . *.:. : * . : : :: . *. : .* . . : * :: :****:*:..::: * * .:. : . : *:: : . :: :. :. * * :: . : : :.. .: : : :: . : * ::: * .: * : . . . : ", "identical_positions": 18, "similar_positions": 71, "identity": "2.94%" }, { "cls_id": "homologset.agr.SGD:S000005707", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70315-1", "uniprot_id": "WASP_MOUSE", "id": "P70315-1", "name": "Actin nucleation-promoting factor WAS", "aln": "MNSGPGPVGGRPGGRGGPAVQQNIPSNLLQDHENQRLFELLGRKC-WTLATTVVQLYLALPPGAEHWTMEHCGAVCFVKDNPQKSYFIRLYGLQAGR-LLWEQELYSQLVYLTPTPFFHTFAGDDCQVGLNFADESEAQAFRALVQEKIQKRNQRQSGERRQLPPPPAPINEERRGGLPPVPPHPGGDHGGPSGGPLSLGLVTVDIQNPDITSSRYRGLPAPG------PGPTDKKRSG---KKKISKADIGAPSGFKHVSHVGWDPQNGFDVN--NLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPPPPCRGGGGGGGGGGGGGGGGGGQPLRPPVVGS-----NKGRSGPLPP---VPMGGAPPP-----------------PTPRG-----PPPPGRGG-------------------------------PPPPPP------------------------------PATGRSGPPPPPLPGAGGPPAPPPPPPPPPPPPCPGSGPAPPP-LPP-----TPVSGGS-----------------------PAPGGGRGALLDQIRQG------------------IQLNKTPGALENSVQQPPAQQ-SEGLVGALMHVMQKRSRVIHSSDEGEDQTGED--EEDDEWDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42768-1", "uniprot_id": "WASP_HUMAN", "id": "P42768-1", "name": "Actin nucleation-promoting factor WAS", "aln": "-MSG-GPMGGRPGGRGAPAVQQNIPSTLLQDHENQRLFEMLGRKC-LTLATAVVQLYLALPPGAEHWTKEHCGAVCFVKDNPQKSYFIRLYGLQAGR-LLWEQELYSQLVYSTPTPFFHTFAGDDCQAGLNFADEDEAQAFRALVQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPG------PSPADKKRSG---KKKISKADIGAPSGFKHVSHVGWDPQNGFDVN--NLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPPPPSRGGN---------------QLPRPPIVGG-----NKGRSGPLPP---VPLGIAPPP-----------------PTPRG-----PPPPGRGG-------------------------------PPPPPP------------------------------PATGRSGPLPPPPPGAGGPPMPPPPPPPPPPP-SSGNGPAPPP-LPP-----ALVPAGG-----------------------LAPGGGRGALLDQIRQG------------------IQLNKTPGAPESSALQPPPQS-SEGLVGALMHVMQKRSRAIHSSDEGEDQAGDE--DEDDEWDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O08816-1", "uniprot_id": "WASL_RAT", "id": "O08816-1", "name": "Actin nucleation-promoting factor WASL", "aln": "----------MSSGQQPPRRVTNVGSLLLTPQENESLFSFLGKKC-VTMSSAVVQLYAADRN--CMWSKKCSGVACLVKDNPQRSYFLRIFDIKDGK-LLWEQELYNNFVYNSPRGYFHTFAGDTCQVALNFANEEEAKKFRKAVTDLLGRR-QRKSEKRRDAP-------------------------NGP-----NLPMATVDIKNPEITTNRFYSSQVNN------ISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGWDPNTGFDLN--NLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQA--PPPPPPSRGGPP--------------PPPPPPHSSGPPPPPARGRGAPPPPPSRAPTAAPPPP-----------------PPSRPGVVVPPPPPNRMY-------------------------------PPPPPAL-----------------------------PSSAPSGPPPPPPLSMAGSTAPPPPPPPPPPP-----GPPPPPGLPSDGDHQVPASSGNKAALLDQIREGAQLKKVEQNSR-PVSCSGRDALLDQIRQG------------------IQLKSVSDGQESTP--PTPAP-TSGIVGALMEVMQKRSKAIHSSDEDEDDDDEEDFQDDDEWED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VAT0-1", "uniprot_id": "Q9VAT0_DROME", "id": "Q9VAT0-1", "name": "", "aln": "-------MSSGMRSQDGPRAKVNAASTLLTQEENEAVFKLLGKKC-QTLNTAVVQIYKTEGSAHAHWKKRHTGVVCFVKDSAIRSYFMRAYCLIKNE-LIWEHEIYDGMEVVKSRPFLLTFEGSDGHVGLNFVSEEECDSFFRIVDATIETRNRKRQEKRNRQKSQQAPN--------APLPQVQREPARPPPMQGGLSSTDGVQLRNNKINSVTLTPAPAPAQSKNFLSSSFGLGNNAKDKKRKVTKADISRPTNFVHLSHVGWDAQKGFDLAGNENDEVLNEFFVKAGVSEVELKDRDTRAFIYDFIQSNNVLASVKQYSVESPTETAAPMPP-------------------PVPTRHPSNG-----NQRTAPPLPPARQPPPAVPVTV-----------------PGAARAPPPPNRPPPIST-------------------------------APPPPPV-----------------------------SAPVVAPPPPPPPPPAAVPPPPPPPMPVGEIPVITTTHAPTQAARPA-----APAAPDPRNALMDAIRKGTQLKKVDTTALSTGSGDSRSDLMKDIRQG------------------TVLKPAKERELGSQRNSDSGAGTDALADALRRALAARGNAIHSDEDETESSDNE-----GEWD-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12446-1", "uniprot_id": "LAS17_YEAST", "id": "Q12446-1", "name": "Proline-rich protein LAS17", "aln": "-------------------------MGLLNSSDKEIIKRALPKASNKIIDVTVARLYIAYPDKNEWQYTGLSGALALVDDLVGNTFFLKLVDINGHRGVIWDQELYVNFEYYQDRTFFHTFEMEECFAGLLFVDINEASHFLKRVQKRERYANRKTLLNKNAVALTKKVRE-------EQKSQVVHGPRGESLIDNQRKRYNYEDVDTIPTTKHKAPPPPPPTAETFDSDQTSSFSDINSTTASAPTTPAPALPPASPEVRKEETHPKHSLPPLPNQFAPLPDPPQHNSPPQNNAPSQPQSNPFPFPIPEIPSTQSATNPFPFPVPQQQFNQAPSMGIPQQNRPLPQLPNRNNRPVPPPPPMRTTTEGSGVRLPAPPPPPRRGPAPPPPPHRHVTSNTLNSAGGNSLLPQATGRRGPAPPPPPRASRPTPNVTMQQNPQQYNNSNRPFGYQTNSNMSSPPPPPVTTFNTLTPQMTAATGQPAVPLPQNTQAPSQATNVPVAPPPPPASLGQSQIPQSAPSAPIPPTLPSTTSAAPPPPPAFLT--QQPQSGGAPAPPPPPQMPATSTSGGGSFAETTGDAGRDALLASIRGAGGIGALRKVDKSQLDKPSVLLQEARGESASPPAAAGNGGTPGGPPASLADALAAALNKRKTKVGAHDDMDNG-----DDW--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ::: : * : . : :*.::* : *. .:*.* .::*:: : . ::*::*:* : :: ** . ..* *.. .*.. * * :: .:. . :: . .. :.. . *. .: : ..: .: : . .: .: :: . : : : . :.. * * ** * . . * . ** .****. :. . . *** . . * .. . * ... . *. . .*. *: .** . *: . .. . . . :* .: . ::. :. .: .:* ", "identical_positions": 45, "similar_positions": 124, "identity": "6.68%" }, { "cls_id": "homologset.agr.SGD:S000005708", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q05474-1", "uniprot_id": "UBIM_RAT", "id": "Q05474-1", "name": "Ubiquitin-like protein FUBI", "aln": "MQLFVRAQE-LHTLEVTGQETVAQIKAHVASLEGIAPEDQVVLLAGSPLEDEATLG------------QCGVEALTTLEVAGRMLGG-------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62861-1", "uniprot_id": "RS30_HUMAN", "id": "P62861-1", "name": "Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein", "aln": "MQLFVRAQE-LHTFEVTGQETVAQIKAHVASLEGIAPEDQVVLLAGAPLEDEATLG------------QCGVEALTTLEVAGRMLGGKVHGSLARAGKVRGQTPKVAKQEKKKKKTGRAKRRMQYNRRFVNVVPTFGKKKGPNANS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RA98-1", "uniprot_id": "F1RA98_DANRE", "id": "F1RA98-1", "name": "", "aln": "MQLFVRGQS-LHSVQLNGSETVAHIKAQIEALEGLACDDQIISLSGIPLEDDALIC------------QSGIEEFNTLEVSSRLLGGKVHGSLARAGKVRGQTPKVDKQEKRKKRTGRAKRRIQYNRRFVNVVPTFGKKKGPNANS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P0CX34-1", "uniprot_id": "RS30B_YEAST", "id": "P0CX34-1", "name": "Small ribosomal subunit protein eS30B", "aln": "----------------------------------------------------------------------MAKVHGSLARAGKVKS---------------QTPKVEKTEKPKKPKGRAYKRLLYTRRFVNVTLVNGKRRMNPGPSVQ", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VDH8-1", "uniprot_id": "Q9VDH8_DROME", "id": "Q9VDH8-1", "name": "", "aln": "MQLFVRGLETIEALEVSQDATIAGVKNQLAQIHGFNAEEFSLDCEGITLANETPVTALSSFELDLNIPMLGGKVHGSLARAGKVKG---------------QTPKVEKQEKKKKKTGRAKRRIQYNRRFVNFVQGFGRRRGPNANST-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* :.:: . ", "identical_positions": 1, "similar_positions": 7, "identity": "0.68%" }, { "cls_id": "homologset.agr.SGD:S000005710", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KAC0-1", "uniprot_id": "A0A0G2KAC0_RAT", "id": "A0A0G2KAC0-1", "name": "Phosphoserine aminotransferase", "aln": "-MEATKQVVNFGPGPAKLPYSVLLEIQKQLLDYKGLGISVLEMSHRSPDFAKIISNTENLVRELLAVPNNYKVIFVQGGGTGQFSAVPLNLIGLKAGR-----CADYVVTGAWSAKAAEEAKKFGT-----VNIVHPKLGSYTKIPDPSTWN---LNPDASYVYFCANETVHGVEFDFIPDVKGAV----LVCDMSSNFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLG------------FALRECPSVLDYKVQAGNNSLYNTPPCFSIYVMDMVLEWIKNNGGAAAMEKLSSVKSQMIYEIIDNSQGFYVCPVERQNRSRMNIPFRIGNSKGDEALEKRFLDKAVELNMISLKGHRSVGGIRASLYNAVTTEDVEKLAAFMKNFLEMHQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99K85-1", "uniprot_id": "SERC_MOUSE", "id": "Q99K85-1", "name": "Phosphoserine aminotransferase", "aln": "-MEATKQVVNFGPGPAKLPHSVLLEIQKQLLDYRGLGISVLEMSHRSSDFAKIIGNTENLVRELLAVPNNYKVIFVQGGGSGQFSAVPLNLIGLKAGR-----SADYVVTGAWSAKAAEEAKKFGT-----VNIVHPKLGSYTKIPDPSTWN---LNPDASYVYFCANETVHGVEFDFVPDVKGAV----LVCDMSSNFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLG------------FSLRECPSVLDYKVQAGNNSLYNTPPCFSIYVMGMVLEWIKNNGGAAAMEKLSSIKSQMIYEIIDNSQGFYVCPVERQNRSRMNIPFRIGNAKGDEALEKRFLDKAVELNMISLKGHRSVGGIRASLYNAVTTEDVEKLAAFMKNFLEMHQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y617-1", "uniprot_id": "SERC_HUMAN", "id": "Q9Y617-1", "name": "Phosphoserine aminotransferase", "aln": "-MDAPRQVVNFGPGPAKLPHSVLLEIQKELLDYKGVGISVLEMSHRSSDFAKIINNTENLVRELLAVPDNYKVIFLQGGGCGQFSAVPLNLIGLKAGR-----CADYVVTGAWSAKAAEEAKKFGT-----INIVHPKLGSYTKIPDPSTWN---LNPDASYVYYCANETVHGVEFDFIPDVKGAV----LVCDMSSNFLSKPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLG------------FALRECPSVLEYKVQAGNSSLYNTPPCFSIYVMGLVLEWIKNNGGAAAMEKLSSIKSQTIYEIIDNSQGFYVCPVEPQNRSKMNIPFRIGNAKGDDALEKRFLDKALELNMLSLKGHRSVGGIRASLYNAVTIEDVQKLAAFMKKFLEMHQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VAN0-1", "uniprot_id": "SERC_DROME", "id": "Q9VAN0-1", "name": "Phosphoserine aminotransferase", "aln": "------MVINFAAGPAKLPEEVLKEVQENLVNCNGSGISVMEMSHRSSNYAKIHDATISDLRELLNVPSNYKILLMQGGGTGQFAAVALNLIG-KTG------TADYVITGSWSAKAAKEAAQYGT-----VNAVLPKLAKYTTVPRQETWK---LDPNASYVYYCDNETVEGVEFDFVPEVPAGVP---LVADMSSNFLSRPFDVSKFGVIYAGAQKNIGPAGTTVIIVRDDLIG------------KHLKITPSILNFEQMDKNNSLLNTPPTFGIYVMGLVFKWIKRNGGVAGMAKLAAAKSKLIYDTINQSNGFYYCPVDVNVRSRMNVPFRIGSASGDDALEKEFLSKAEAEGMIQLKGHRSVGGIRASLYNAVTLAETQQLANLMLAFYKNNKN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33330-1", "uniprot_id": "SERC_YEAST", "id": "P33330-1", "name": "Phosphoserine aminotransferase", "aln": "MSLEREEPQHFGAGPAQMPTPVLQQAAKDLINFNDIGLGIGEISHRSKDATKVIEDSKKHLIELLNIPDTHEVFYLQGGGTTGFSSVATNLAAAYVGKHGKIAPAGYLVTGSWSQKSFEEAKRLHVPAEVIFNAKDYNNGKFGKIPDESLWEDKIKGKAFSYVYLCENETVHGVEWPELPKCLVNDPNIEIVADLSSDILSRKIDVSQYGVIMAGAQKNIGLAGLTLYIIKKSILKNISGASDETLHELGVPITPIAFDYPTVVKNNSAYNTIPIFTLHVMDLVFQHILKKGGVEAQQAENEEKAKILYEALDANSDFYNVPVDPKCRSKMNVVFTLKK----DGLDDQFLKEAAARHLTGLKGHRSVGGFRASIYNALSVKAVQNLVDFIKEFAEKNA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*..***::* ** : ::*:: .. *:.: *:**** : :*: : . : *** :*..:::: :**** *::*. ** . .* *.*::**:** *: :** : . .* : ..: .:* . *: . **** * ****.***: :*. :*.*:**::**: .***::*** ******:* ** *: *::..:: : * ::: *.* ** * * ::**.:*:: * .:**. . *:: :*: :: ...** **: : **:**: * : . :.*:..**.:* : *********:***:***:: .::*. :: * : : ", "identical_positions": 121, "similar_positions": 124, "identity": "30.25%" }, { "cls_id": "homologset.agr.SGD:S000005711", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62826-1", "uniprot_id": "RAN_HUMAN", "id": "P62826-1", "name": "GTP-binding nuclear protein Ran", "aln": "MAAQGE---PQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDD-DL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62828-1", "uniprot_id": "RAN_RAT", "id": "P62828-1", "name": "GTP-binding nuclear protein Ran", "aln": "MAAQGE---PQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDD-DL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62827-1", "uniprot_id": "RAN_MOUSE", "id": "P62827-1", "name": "GTP-binding nuclear protein Ran", "aln": "MAAQGE---PQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDD-DL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q61820-1", "uniprot_id": "RANT_MOUSE", "id": "Q61820-1", "name": "GTP-binding nuclear protein Ran, testis-specific isoform", "aln": "MAAQGE---PQVQFKVVLVGDGGTGKTTFMKRHLTGEFEKEYVATLGVEVHTLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPSWHKDLVRVCENIPIVLCGNKVDVKDMKVKAKPILFHRKKNLQYYDISARSNYNFEKPFFWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEED-DL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K586-1", "uniprot_id": "RANT_RAT", "id": "Q8K586-1", "name": "GTP-binding nuclear protein Ran, testis-specific isoform", "aln": "MAGQGK---PQIQFKLVLVGDGGTGKTTFMKRHLTGEFEKEYVATLGVEVHTLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPSWHKDLVRVCENIPIVLCGNKVDIKDMKVKAKPILFHRKKNLQYYDISAKSNYNFEKPFFWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEED-DL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P79735-1", "uniprot_id": "RAN_DANRE", "id": "P79735-1", "name": "GTP-binding nuclear protein Ran", "aln": "-MAENE---PQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGAIKYNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVEMPALAPPEIAMDPTLAAQYEHDLKVASETALPDEDD-DL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZ23-1", "uniprot_id": "RAN_DROME", "id": "Q9VZ23-1", "name": "GTP-binding nuclear protein Ran", "aln": "MAQEGQ---DIPTFKCVLVGDGGTGKTTFVKRHMTGEFEKKYVATLGVEVHPLIFHTNRGAIRFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLVGDPNLEFVAMPALLPPEVKMDKDWQAQIERDLQEAQATALPDEDE-EL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32836-1", "uniprot_id": "GSP2_YEAST", "id": "P32836-1", "name": "GTP-binding nuclear protein GSP2/CNR2", "aln": "MSAPAQNNAEVPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATIGVEVHPLSFYTNFGEIKFDVWDTAGQEKFGGLRDGYYINAQCAIIMFDVTSRITYKNVPNWHRDLVRVCENIPIVLCGNKVDVKERKVKAKTITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLAGNPQLEFVASPALAPPEVQVDEQLMHQYQQEMDQATALPLPDEDDADL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** *************:***:******:*:**:*****.* *:** * *:::*******************:.***:********:******.**:*******************:*: *****.* **************:*********:****** *:*:**** *** ***: :* * ::::. * .****:: :*", "identical_positions": 151, "similar_positions": 35, "identity": "68.64%" }, { "cls_id": "homologset.agr.SGD:S000005713", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P85834-1", "uniprot_id": "EFTU_RAT", "id": "P85834-1", "name": "Elongation factor Tu, mitochondrial", "aln": "---MAAATLLRATPRFS-GLCASPTPFLQG-RLRPLKAPASPFLCRGLA--------------------VEAKKTYVRDKPHVNVGTIGHVDHGKTTLTAAITKILAEGGGAKFKKYEEIDNAPEERARGITINAAHVEYSTAARHYAHTDCPGHADYVKNMITGTAPLDGCILVVAANDGPMPQTREHLLLAKQIGVEHVVVYVNKADAVQDSEMVELVELEIRELLTEFGYKGEETPVIVGSALCALEQRDPELGVKSVQKLLDAVDTYIPVPTRDLEKPFLLPVESVYSIPGRGTVVTGTLERGILKKGDECELLGHNKN-IRTVVTGIEMFHKSLERAEAGDNLGALVRGLKREDLRRGLVMVKPGSIQPHQKVEAQVYILSKEEGGRHKPFVSHFMPVMFSLTWDMACRVILPPGKE----LAMPGEDLKLSLILRQPMILEKGQRFTLRDGNKTIGTGLVT-DVPAMTE-------EDKNIKWS------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFR5-1", "uniprot_id": "EFTU_MOUSE", "id": "Q8BFR5-1", "name": "Elongation factor Tu, mitochondrial", "aln": "---MAAATLLRATPRFS-GLCASPTPFLQG-RLRPLKAPASPFLCRGLA--------------------VEAKKTYVRDKPHVNVGTIGHVDHGKTTLTAAITKILAEGGGAKFKKYEEIDNAPEERARGITINAAHVEYSTAARHYAHTDCPGHADYVKNMITGTAPLDGCILVVAANDGPMPQTREHLLLAKQIGVEHVVVYVNKADAVQDSEMVELVELEIRELLTEFGYKGEETPVIVGSALCALEQRDPELGVKSVQKLLDAVDTYIPVPTRDLDKPFLLPVESVYSIPGRGTVVTGTLERGILKKGDECELLGHNKN-IRTVVTGIEMFHKSLERAEAGDNLGALVRGLKREDLRRGLVMVKPGSIQPHQKVEAQVYILSKEEGGRHKPFVSHFMPVMFSLTWDMACRVILPPGKE----LAMPGEDLKLSLILRQPMILEKGQRFTLRDGNKTIGTGLVT-DVPAMTE-------EDKNIKWS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49411-1", "uniprot_id": "EFTU_HUMAN", "id": "P49411-1", "name": "Elongation factor Tu, mitochondrial", "aln": "MTTMAAATLLRATPHFS-GLAAGRTFLLQG-LLRLLKAPALPLLCRGLA--------------------VEAKKTYVRDKPHVNVGTIGHVDHGKTTLTAAITKILAEGGGAKFKKYEEIDNAPEERARGITINAAHVEYSTAARHYAHTDCPGHADYVKNMITGTAPLDGCILVVAANDGPMPQTREHLLLARQIGVEHVVVYVNKADAVQDSEMVELVELEIRELLTEFGYKGEETPVIVGSALCALEGRDPELGLKSVQKLLDAVDTYIPVPARDLEKPFLLPVEAVYSVPGRGTVVTGTLERGILKKGDECELLGHSKN-IRTVVTGIEMFHKSLERAEAGDNLGALVRGLKREDLRRGLVMVKPGSIKPHQKVEAQVYILSKEEGGRHKPFVSHFMPVMFSLTWDMACRIILPPEKE----LAMPGEDLKFNLILRQPMILEKGQRFTLRDGNRTIGTGLVT-NTLAMTE-------EEKNIKWG------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z9E3-1", "uniprot_id": "A1Z9E3_DROME", "id": "A1Z9E3-1", "name": "Elongation factor Tu", "aln": "MSHAFAAAVCRSTASMSLALRCSRRAMSSARMLRMAGATATSTACKDWQRNGLLAAPRTGNMQQYLREYANEKKVFERTKPHCNVGTIGHVDHGKTTLTAAITKVLADKQLAESKKYNEIDNAPEEKARGITINVAHVEYQTETRHYGHTDCPGHADYIKNMITGTAQMDGAILVVAATDGAMPQTREHMLLAKQIGIDHIVVFINKVDAA-DEEMVDLVEMEIRELLTEMGYDGDKIPVVKGSALCALEDKSPEIGKEAILKLLQEVDSFIPTPVRELDKPFLLPVENVYSIPGRGTVVTGRLERGVVKKGMECEFVGYNKV-LKSTVTGVEMFHQILEEAQAGDQLGALVRGVKRDDIKRGMVMCKPGSVKALDQLEAQVYILSKDEGGRTKPFMSFIQLQMFSRTWDCAVQVQIP-DKE----MVMPGEDTKLILRLIRPMVLEQGQRFTLRDGNLTLGTGVVTSTLPPLTESQRSELTEGKKAREKKVAAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P02992-1", "uniprot_id": "EFTU_YEAST", "id": "P02992-1", "name": "Elongation factor Tu, mitochondrial", "aln": "MSALLPRLLTRTAFKAS------------GKLLRLSSVISRTFSQTTTS----------------------YAAAFDRSKPHVNIGTIGHVDHGKTTLTAAITKTLAAKGGANFLDYAAIDKAPEERARGITISTAHVEYETAKRHYSHVDCPGHADYIKNMITGAAQMDGAIIVVAATDGQMPQTREHLLLARQVGVQHIVVFVNKVDTIDDPEMLELVEMEMRELLNEYGFDGDNAPIIMGSALCALEGRQPEIGEQAIMKLLDAVDEYIPTPERDLNKPFLMPVEDIFSISGRGTVVTGRVERGNLKKGEELEIVGHNSTPLKTTVTGIEMFRKELDSAMAGDNAGVLLRGIRRDQLKRGMVLAKPGTVKAHTKILASLYILSKEEGGRHSGFGENYRPQMFIRTADVTVVMRFPKEVEDHSMQVMPGDNVEMECDLIHPTPLEVGQRFNIREGGRTVGTGLIT----RIIE---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *:: * . ** . : . .: * *** *:******************* ** *: .* **:****:******..*****.* ***.*.********:******:* :**.*:****.** *******:***:*:*::*:**::**.*: * **::***:*:****.* *:.*:: *:: ******** :.**:* ::: ***: ** :**.* *:*:****:*** ::*:.******** :*** :*** * *::*:.. :::.***:***:: *: * ***: *.*:**::*::::**:*: ***:::. :: *.:*****:**** . * . ** * * : : :* * .***:: :: * :* ** ****.:*:*. *:***::* : * ", "identical_positions": 215, "similar_positions": 117, "identity": "43.35%" }, { "cls_id": "homologset.agr.SGD:S000005717", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P34739-1", "uniprot_id": "TTF2_DROME", "id": "P34739-1", "name": "Transcription termination factor 2", "aln": "---------------------------------------------MSSENSEYYSDKEEDSVVNNSSLGRSRKSSRLSKSSRLSKSSRPSSAGVVIDETQSEEEESQSSETAESEKSDES-------------DNSQNSQESEDSEDDSVRPSARNTKRKPLGIPSDSEDEEDE-----------------LEQRALSPSTRMSITGVRPQDLSDDDSEIEYSDEVQ---------------------EGPTEAPTAEAVVPRYTTQFAGNIQNDLHSTIGAADSEVLDDSSG---------------------------------------------SDVLILSNKETPIEILSSTDDDATTNKENMS----------------------------------------------------GPPFERPSKSLSPRSSAGASVVKTSKNLSQPT-IQAVLKQKTSPAAPRRSRIKSEDQKVVSQVVYDEE----------------MRKLAEKRVQVSDAEKLFEKVAHKLPDKGSQIMKRIDTLRRELAMDEQWISALRVQQSNVPAVRVVKPTLNPPRAPSIDTLDWDELSEAVNEIKPVYTGAQGMATFNNQKALTLE-----------------------------------------------------SLKDLHVSLEDLPGPEVLAEDP--VGLKVSLMNHQKHALAWMSWRERKLPRGGILADDMGLGKTLTMISS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VLACKNGQEMSEGKDESSDSDSEDDKNKKRK-----------------------------SVTGWKSKGRKDTRRGGTLVVCPASLLRQWESEVESKVSR-QKLTVCVHHGN-NRETKG-KYLRDYDIVVTTYQIVAREHK-------------------------------SLSAVFG--VKWRRIILDEAHVVRNHKSQSSLAVCDLRGKYRWALTGTPIQNKELDVYALLKFLRCSPFDDLHTWKKWIDNKSAGGQ-------------NRLNLLMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLHQRAERETDFNYRSDANKPTYNQIKDPNGAYYKMHEKFARMAGSK--KEVKSHDILVLLLR----------LRQICCHPGLIDAMLD----GEESQTMGDHSSDSD-TPEIDLLAQLNKLAITDTS---TDGQQSVANAGDDGPPLLPDEARIAKASKN----------------------LLKRSNPVFNLHRPSSKINMVIQILKTSILKSSDDKAIVVSQWTSVLDILRDHLS-KDGVATLSLNGTIPVKNRQDIVNEFNDRNNQKRVLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDTVEQRIKGLQDKKLDLADGVLTG------AKVSSKLTIDDLKGLFGM---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VHY2-1", "uniprot_id": "Q9VHY2_DROME", "id": "Q9VHY2-1", "name": "Transcription termination factor 2", "aln": "-----------------------------------------------------------------------------MESSSPSDTTEIHKQSCSIQDQSSVPVPDSSGEINNWMEPEPV-------------DSLELSGEYADNESAIFVSASEYNEKK---------AQIDQ-----------------LVQKILTMEQ-------QQRQLEENASETKELCDLK---------------------LHLEKLN--------ARLEALGEFLDTLRLREDQQEIKIEDNS------------------------------------------------------------ELVDHTEQPKWSNLYSGL----------------------------------------------------NRYRQKANHTAAQFYQHKSNIIDSLKTLYEPIQPRPAIDDLEKQPALLLVRLLKHQQSCLKWMQFRER----------------QKISGGILADDMGLGKTLSMIALILASEETKNRKREEKKK---ALTLKWTQEFNR--------------------------------VYCKEIRKISMFDDEEESGKEEEQYEPP-----------------------------------------------------EKRTCHVKTKKINQFRILDDDDNDAGDKAVVEDEQKDLLAKT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PEPEVFSSDEEEEHLSNGRYP-----------------------------SAN--------------TLVVCPMSVMCQWAHEVASKVAQ-NAIRVLTFHGP-NRHEIGIEAFRSYDLVITSYNLVVNELKRYG----------------------------NTSPLFA--VYWNRVILDEAHIIRNSKTNCCNSVCQLRAHCHWALTGTPVQNRGVDVFALLRFVNVPNFQDLQQWKKNLN-ESMLGH-------------RRLNFIIKPLMLRRTKQKLQASGDMPALPSLKIELICVQLSKTEMAVYQILSAISKKIFTQFLLQREKGNSDLNYYSLERTPQFIAGHMSDERYNEIYERFLKSLGYNPGEKILGIYILVLLLR----------LRQFCCHPGLMIGMLRGALTAEDVQNVKVDASDVEGQLKMDVLAELDKFDETDSEDDCCDEEDSTRRDGNFKLEVIKDEIKEENVPWDSGDDLPTASSFEDQLDSARALKLLNPQNPIFQFIRPSAKLKMVIDKLEELLTG-TNDKIIVTSQWVSYLAIVRKRLQ-DLSWETLDFNGQLTAKEREIVLRDFN-ANNEKRVLLLSLTAGGVGLNLNVANHMLIVDLHWNPQLERQAQDRIYRYGQTKPTFIYRYMCQDTVEQRIKSLQDCKLEIAKVVLPEEGGEVTKCVGGGLNLAELKKLFEM---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08562-1", "uniprot_id": "ULS1_YEAST", "id": "Q08562-1", "name": "ATP-dependent chromatin remodeler/ubiquitin-protein ligase E3 ULS1", "aln": "MAAVPTIDLTLADSDNEDIFHSFSSSTSVDKIDIRKENGKLRMAGLEVAQSNDDAARQAFHVFKTNISNNETFDTILSKSKTITDSTFNNEKSSNEVKQQQVLKEETMGSSNDEKKTQESSPSAEMIKLFYENDDVPLSDSFKQKEEGKRINQDEQVKENICGISSSYVSKDYDGVEDDFEPNTCQDSNLDFQEEKLNLNNKPSQQQFSDPETKDNSLKSENKDQIKGVTTTSYRDLPIESSAFQDSETQNNSKNTIPNIVNEKRTPALPSNLSSVESSLKNETAKVEGKTTVRLPGLQNNVALLEQEQSELFKHFSEQPVDISDFGRKIKRKHSGDFADNKILKRPILPSKNMDHTTHNSHDSEQKNSSIIILSDEDESGAGINDIESPLKVSEPNTADALRSSVPEVISLLDLPNIDLNNSVIKEASGSNSIPTSETDAQSSSSSVLQGTIMTEQATQSSQHECNSSLDTLKKNHQKLLKDLNSRESELRNALSCCKTNSEILRRKLSRREKEVSDAEKHWQLLLTSMARGGRTISSTQQILVDEAENQLNKLKEKRQLTKSKLDSINLKMYNYNEQWKSFVHSKNINLQKSLAALERSARDSKASATVNKRNECLAEKEKLDQMLKEGTLSFSTYKQLTGEIQQKLNDLKLGDQRTTDINSVLPIVRQPLAKRDLFIKSIDTAKDLLAKNTSRTEMTKRILYRHLDNLVSYKNFFEDGRSLIDINRRHVAHESAQILFTNGVKMPIVFETLQDYGIKFSNPAIVNPDRRAQYFKSIEVARDLISKSTRSEDAKRKITRFLNIIEEFRKDIDTGFPPTPLKREGVGKAVVGLRQQGLKMDRLYENLRRYKIPITSEELLQQSYLFPVNADQRPPSNWNIVENTEDTSSTANDLSMQDEFHISNMHAAEDQEQIRALLENVKQSESIIDGEALTPEDMTVNLLKHQRLGLHWLLQVENSAKKGGLLADDMGLGKTIQAIALMLANRSEESKCKTNLIVAPVSVLRVWKGELETKVKKRAKFTTFIFGGSGNGKVKHWRDLARYDAVLVSYQTLANEFKKHWPKKLDGEQNQLPAVPHIQALNRLKTSNEYYSPFFCNDSTFYRILLDEGQNIKNKNTRASKACCTINGMYRWVLSGTPIQNSMDELYSLIRFLRIPPYHKEQRFKLDIGRFFQRNKQYQYDNEDRKNALRKVRVLLNAIMLRRSKADKIDGKPLLELPPKIVEVDESRLKGEELKFYTALESKNQALAKKLLNNSTRGSYSSVLTLLLRLRQACCHSELVVMGEKKAEGTKVANGKSFEDDWLRLYYKITHMSGEAQAQVITSMNSMTCFWCMEQLEPEAMSVLTGCGHLICDTCIEPFIEESSMLPQAKKTKGGAFAIPCKDCQRLTNEKDIVSHKLYDQVINQGFTEEDLHAEYLSEME-------KQKIQQKNVYVPNFESLEPSTKIEQCIQVIQRVFDESATEKIIIFSQFTTFFEILEHFLKNKLNFPYLKYIGSMNAQRRSDVINEFY-RDPEKRILLISMKAGNSGLTLTCANHVVIVDPFWNPYVEEQAQDRCYRISQTKKVQVHKLFIKDSVEDRISELQKRKKEMVDSAMDPG----KIKEVNSLGRRELGFLFGLNAL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. :.:: . . . .. . .. : :.: *. * . :.*. . :.: : : : :. *. . : .:: : : ::: . . . :. :: ..: : :. * . . . . :... : : . .: . * . . . .. : ...*. :. : * : . : . * . : :. . : : . . :. . : ::.: : .:. . : : * : . .. :: : : :.:. . : : : .*:*.* *:: * *: :** : : . . * * . . : ** *:.:*: :..* * *..* : *::***.: ::* ::... : * :.. :*.*:***:** ::::*::*:. . :.. : :* :. .: .::..:::.:****:* . . : ** :.: *. *: .* : : .: : ::* : . . . . : * * . .. : : :..: *. : : .:. : .:*.: .* * : . . . : : . . : : * *: .**:*:: *: :: : : :* *: **:.: : *:.. *. . . *. * : .:.*. ::.:* : :**:**:*:.**. **.* ***::::* .*** :* ***** ** .*.* . ::: : *:**:**. **. * ::.. .: . * :* ** : ", "identical_positions": 117, "similar_positions": 318, "identity": "7.17%" }, { "cls_id": "homologset.agr.SGD:S000005720", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08949-1", "uniprot_id": "TF2AA_RAT", "id": "O08949-1", "name": "Transcription initiation factor IIA subunit 1", "aln": "----------------------------------------------MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQ---------------------------------------------------QQQHHHHHH-HQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASSITSAAATAATLALPAGVT---PVQQILTNSGQLLQVVRAANG--------------------AQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQ---QILFTGNKTQVIPTTVAAPTPAQAQIPAAGQQQPQAQPAQQQAPLVLQVDGTGDTSSEEDEDEEEDYDDD---------------------EEEDKEKDGAEDGQ-----VEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52655-1", "uniprot_id": "TF2AA_HUMAN", "id": "P52655-1", "name": "Transcription initiation factor IIA subunit 1", "aln": "----------------------------------------------MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQ---------------------------------------------------QQQHHHHHH-HQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMS-AAATAATLALPAGVT---PVQQILTNSGQLLQVVRAANG--------------------AQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQ---QILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDD---------------------EEEDKEKDGAEDGQ-----VEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99PM3-1", "uniprot_id": "TF2AA_MOUSE", "id": "Q99PM3-1", "name": "Transcription initiation factor IIA subunit 1", "aln": "----------------------------------------------MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQ---------------------------------------------------QQQHHHHHHQHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLLQHMNASSITSAAATAATLALPAGVT---PVQQLLTNSGQLLQVVRAANG--------------------AQYILQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQ---QILFTGNKTQVIPTTVAAPAPAQAPMPAAGQQQPQAQPAQQQAPLVLQVDGTGDTSSEEDEDEEEDYDDD---------------------EEEDKEKDGAEDGQ-----VEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8R4I4-1", "uniprot_id": "TF2AY_MOUSE", "id": "Q8R4I4-1", "name": "TFIIA-alpha and beta-like factor", "aln": "-------------------------------------------------MAFINLVPKLYQSVIEDVIEGVRDLFAEEGIEEQVLKDLKKLWETKVLQSKATEDFFRNSTQVPLLTLQLPHALPPALQP-EASLLIPAGRTLPSFTPEDLNTANCGANFAFAGYPIHVPAGMAFQTASGHLYKVNVPVMVTQTSGRTEILQHPFQQVLQQLGQPLVIQTTVPTLHPCSLQAATEKSLRMEAVLQPPPILHPPPVDRTHVENAASDRRLLPGNE--------LRPQESSPYLSLPGVGFPPQAALTESSLEPVLGVSASLTQNLHSDPFSQGPPGPLHHHLLESQLQSLKDSIYGCDSTKQLRKAEEPSSLRVSEKNCTSERDLNIRVTDDDINEIIQIDGTGDNSSTEEMGSIRDADENEFPGIIDAGDLNVL-EEVDSVSNEDSTANSSDNEDHQINAPEEDPLNSGDDVSEQDVPDLFDTENVIVCQYDKIHRSKNRWKFYLKDGVMCFGGRDYVFAKAIGEAEW-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F7R8-1", "uniprot_id": "F7F7R8_RAT", "id": "F7F7R8-1", "name": "", "aln": "MLAFSFSILGESSAPSGLAVAQQRAPAVQKRAWRLSATQAQTVGRRAASMAFVNLVPKLYRSVIEDVIEGVRDLFAEEGIEEQVLKDLKKLWETKVLQSKATEDFFRNSVQAPLFTLQLPHGLPPALQS-TASLLIPAGRTLQSFTPEDLN-ASCAANFAFPGYPIHVPAGMALQTASGHLYKVNVPVVVTQTSGRAEILQHPFQQVLQQLGQPSIIQTTVPTLHPCSLQAETEKSHRMETALQQPTVLHSTPVDRKHTENATSERRVLPGNE--------LRPQESTQYISLPGVGFPPQVALTESSLEPVLGASANLTQNLHGGPFTQGPPGTLRHHVLDTQLHSLRDRIYGCDSVKQLRKIEEPSSLRVSEKSCTSERDLNIQVTDDDINEIIQIDGTGDNSSAEEGGSIRDADENEFPGIIEAGDLKVLEEEVDSVSNEDSTANSSDNEDHQIDALEEDPLNSGDDVSEQDAPDLFDTDNVIVCQYDKIHRSKNRWKFYLKDGVMCFGGRDYVFAKAIGEAEW-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UNN4-1", "uniprot_id": "TF2AY_HUMAN", "id": "Q9UNN4-1", "name": "TFIIA-alpha and beta-like factor", "aln": "-------------------------------------------------MACLNPVPKLYRSVIEDVIEGVRNLFAEEGIEEQVLKDLKQLWETKVLQSKATEDFFRNSIQSPLFTLQLPHSLHQTLQSSTASLVIPAGRTLPSFTTAELGTSNSSANFTFPGYPIHVPAGVTLQTVSGHLYKVNVPIMVTETSGRAGILQHPIQQVFQQLGQPSVIQTSVPQLNPWSLQATTEKSQRIETVLQQPAILPSGPVDRKHLENATSDILVSPGNEHKIVPEALLCHQESSHYISLPGVVFSPQVSQTNSNVESVLSGSASMAQNLHDESLSTSPHGALHQHVTDIQLHILKNRMYGCDSVKQPRNIEEPSNIPVSEKDSNSQVDLSIRVTDDDIGEIIQVDGSGDTSSNEEIGSTRDADENEFLGNIDGGDLKVPEEEADSISNEDSATNSSDNEDPQVNIVEEDPLNSGDDVSEQDVPDLFDTDNVIVCQYDKIHRSKNKWKFYLKDGVMCFGGRDYVFAKAIGDAEW-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52654-1", "uniprot_id": "TF2AA_DROME", "id": "P52654-1", "name": "Transcription initiation factor IIA subunit 1", "aln": "------------------------------------------------MALCQTSVLKVYHAVIEDVITNVRDAFLDEGVDEQVLQEMKQVWRNKLLASKAVELSPDSGD----------------------------------------------------------------GSHPPPIVANNPKSHKAANAKAKKAAAATAVTSHQHIGGNSSMSSLVGLKSSAGMAAGSGIRNGLVPIKQEVNSQNPPPLHPTSAASMMQKQQQAASSG------------------QGSIPIVATLDPNRIMPVNITLPSPAGSASSESRVLTIQVPASALQENQLTQILT----------AHLISSIMSLPTTLASSVLQQHVNAALSSANHQKTLAAAKQLDGALDSSDEDESEESDDNIDN---------------------DDDDDLDKDDDEDAEHEDAAEEEPLNSEDDVTDEDSAEMFDTDNVIVCQYDKITRSRNKWKFYLKDGIMNMRGKDYVFQKSNGDAEW-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32773-1", "uniprot_id": "TOA1_YEAST", "id": "P32773-1", "name": "Transcription initiation factor IIA large subunit", "aln": "--------------------------------------------------MSNAEASRVYEIIVESVVNEVREDFENAGIDEQTLQDLKNIWQKKLTETKVTTFSWDNQFN--------------------------------------------------------------------EGNINGVQNDLNFNLATPGVNSSEFNIKEENTGNEGLILPNINSNNNIPHSGETNINTNTVEATNNSGAT----LNTNTSGNTNADVTSQ------------------------PKIEVKPEIELTINNANITTVENIDDESEKK-------------------------------------DDEEKEEDVEKTRKEKEQIEQVKLQAKKEKRSALLDTDEVGSELD-----------------------------------------------------------DSDDDYLISEGEEDGPDENLMLCLYDKVTRTKARWKCSLKDGVVTINRNDYTFQKAQVEAEWV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::*. ::*.*: **: * : *::**.* ::* :*..*: ::.. . . :: : . : :. . . . . . : . . : * . . :* ** .: : :*:::* ***: *:: :** ****:: : .** * *: :*** ", "identical_positions": 36, "similar_positions": 61, "identity": "6.82%" }, { "cls_id": "homologset.agr.SGD:S000005722", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIH4-1", "uniprot_id": "LIAS_RAT", "id": "Q5XIH4-1", "name": "Lipoyl synthase, mitochondrial", "aln": "MALR------CWDAARSLGSRIFG----------------------RYACS-VRALSSLP------------------DEKKKFLHNGPDLQDFVSGDLADKSTWDDYKGNLKRQKGE--RLRLPPWLKTKIPMGKNYNKLKNTLRNLNLHTVCEEARCPNIGECWGGGEYATATATIMLMGDTCTRGCRFCSVKTARNPPPLDPSEPDNTARAIAEWGLDYVVLTSVDRDDVVDGGAEHIAKTVSCLKERNPKILVECLTPDFRGDLRAVEKVALSGLDVYAHNVETVPELQRKVRDPRANFDQSLRVLKHAKEVQPDVVSKTSIMLGLGETDEQVYATMKALRAADVDCLTLGQYMQPTKRHLKVEEYVTPEKFKYWEEVGNELGFHYTASGPLVRSSYKAGEFFLKNLVAKRKTKVSKV------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99M04-1", "uniprot_id": "LIAS_MOUSE", "id": "Q99M04-1", "name": "Lipoyl synthase, mitochondrial", "aln": "MALR------CWDTARSLGSRIFG----------------------RYAFT-VRALSSLP------------------DKKKEFLHNGPDLQDFVSGDLADKSTWDEYKGNLKRQKGE--RLRLPPWLKTKIPMGKNYNKLKNTLRNLSLHTVCEEARCPNIGECWGGGEYATATATIMLMGDTCTRGCRFCSVKTARNPPPLDANEPDNTAKAIAEWGLDYVVLTSVDRDDVADGGAEHIAKTVSCLKERNPKILVECLTPDFRGDLRAVEKVALSGLDVYAHNVETVPELQRKVRDPRANFDQSLRVLRHAKEVQPDVVSKTSIMLGLGETDEQVYATLKALRAADVDCLTLGQYMQPTKRHLKVEEYVTPEKFKYWEKVGNELGFLYTASGPLVRSSYKAGEFFLKNLVARRKTKASKV------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43766-1", "uniprot_id": "LIAS_HUMAN", "id": "O43766-1", "name": "Lipoyl synthase, mitochondrial", "aln": "MSLR------CGDAARTLGPRVFG----------------------RYFCSPVRPLSSLP------------------DKKKELLQNGPDLQDFVSGDLADRSTWDEYKGNLKRQKGE--RLRLPPWLKTEIPMGKNYNKLKNTLRNLNLHTVCEEARCPNIGECWGGGEYATATATIMLMGDTCTRGCRFCSVKTARNPPPLDASEPYNTAKAIAEWGLDYVVLTSVDRDDMPDGGAEHIAKTVSYLKERNPKILVECLTPDFRGDLKAIEKVALSGLDVYAHNVETVPELQSKVRDPRANFDQSLRVLKHAKKVQPDVISKTSIMLGLGENDEQVYATMKALREADVDCLTLGQYMQPTRRHLKVEEYITPEKFKYWEKVGNELGFHYTASGPLVRSSYKAGEFFLKNLVAKRKTKDL--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PHG4-1", "uniprot_id": "LIAS_DANRE", "id": "Q6PHG4-1", "name": "Lipoyl synthase, mitochondrial", "aln": "MALISR---SCGAASRYSSSHLFLPSKGAEAANVYCN---------RLSTAASTSSSSSPSPST------------HNDRKKDLREDGLNLQDFISGELSEKSKWEEYRGNLKREKGE--RLRLPPWLKTEIPIGKNYNKLKNTLRELNLHTVCEEARCPNIGECWGGGEYATATATIMLMGDTCTRGCRFCSVKTARRPPPLDPDEPYNTAKAIAAWGLDYVVLTSVDRDDIPDGGAEHFAKTVSNIKERNSKILVECLTPDFRGDLAAVEKIALSGLDVYAHNVETVRELQRHVRDPRANFDQSLSVLRHAKKVKSSVLTKTSIMLGLGETDAQIQATLTELRDSGVDCLTLGQYMQPTKRHLKVEEYVTPEKFAFWEKVGQEMGFIYTASGPLVRSSYKAGEFFLKNLLEKRKTEETTATAE---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7JQW6-1", "uniprot_id": "LIAS_DROME", "id": "Q7JQW6-1", "name": "Lipoyl synthase, mitochondrial", "aln": "-MLR-------ALKTHAEAPIVVAT---------------------RAASTNAEKLEEIR----------------------ERLAKGPNFHDFVQNPDNTRNEWEQYDGKLRREKGEEQRLRLPPWLKTTIPVGKNYAKIKAQMRELKLSTVCEEARCPNIGECWGGGEHGTQTATIMLMGDTCTRGCRFCSVKTARKPPPLDVNEPVNTATAIASWGLDYIVLTSVDRDDLPDGGSEHIAETVREIKARNSNIFVECLVPDFRGNLECVKTIANSGLDVYAHNIETVEKLTPYVRDRRAHYRQTLQVLTEAKRFNPNLITKSSIMLGLGETDEEIENTLKDLREAGVDCVTLGQYMQPTNKHLKVIEYVTPEKFKHWEERGNELGFLYTASGPLVRSSYKAGEFFITSILENRKKRQNDTEVPKKQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32875-1", "uniprot_id": "LIPA_YEAST", "id": "P32875-1", "name": "Lipoyl synthase, mitochondrial", "aln": "MYRRSVGVLFVGRNTRWISSTIRCGTSATRPIRSNALNTDSDNASVRVPVGNSTEVENATSQLTGTSGKRRKGNRKRITEFKDALNLGPSFADFVSGKASKMILDPLEKARQNTEEAK----KLPRWLKVPIPKGTNYHKLKGDVKELGLSTVCEEARCPNIGECWGGKDKSKATATIMLLGDTCTRGCRFCSVKTNRTPSKPDPMEPENTAEAIKRWGLGYVVLTTVDRDDLVDGGANHLAETVRKIKQKAPNTLVETLSGDFRGDLKMVDIMAQCGLDVYAHNLETVESLTPHVRDRRATYRQSLSVLERAKATVPSLITKTSIMLGLGETDEQITQTLKDLRNIQCDVVTFGQYMRPTKRHMKVVEYVKPEKFDYWKERALEMGFLYCASGPLVRSSYKAGEAFIENVLKKRNMK----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .. : * .. . * .: **:.. .. . ::.: :** ***. ** *.** *:* :::* * ***************** : .. ******:*************** * *. * ** *** ** ***.*:***:*****: ***::*:*:** :* : .: :** * ****:* :. :* .********:*** .* *** ** : *:* ** .** ..:::*:********.* :: *:. ** * :*:****:**.:*:** **:.**** .*:: . *:** * ************** *: .:: .*: . ", "identical_positions": 169, "similar_positions": 86, "identity": "39.49%" }, { "cls_id": "homologset.agr.SGD:S000005727", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZK81-1", "uniprot_id": "D3ZK81_RAT", "id": "D3ZK81-1", "name": "rRNA methyltransferase 1, mitochondrial", "aln": "----------------------------------MLLLWTVG--CFNRLVARHFSSVARPGERPGGEELSRLLLDDLAPAQR----LERLFGVSPCLLALRAARRHVARLLLQAGKAGLQGE-------------------------------------------RAELLRVAEARGIPVLRPRR--------QKLDALCGYQVHQGVCMEVSR----LRPRPCDEAADTSSGDDPQ---------------------------QLWLVLEGIQDPRNLGAVMRSAYFLGVDRVITSRRNSCPLTPVVSKASAG---AMEVMDVFASPDLASFLQAKAQQG---WLVVGTVGCPGPEISQSSKVPVTSCLEFIWDRPTLLVLGNEGSGLSQGVFATCQLLLTILPG------RHLPPGLESLNVSVATGILLHSICSQKKGFPVQ-ERGQRLQDS------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J25-1", "uniprot_id": "MRM1_MOUSE", "id": "Q99J25-1", "name": "rRNA methyltransferase 1, mitochondrial", "aln": "----------------------------------MRRLWTVG--CFSRLIARHFSSVARRGERPGGEELSRLLLDDLAPAQR----LERLFGLSPCLLALRAARRRVARLLLQAGKAGLQGE-------------------------------------------RAELLRVAEARGIPVLRPRR--------QKLDALCGYQVHQGVCMEVSP----LRPRPCDEAADTSSGDDPQ---------------------------QLWLVLEGLQDPRNLGAVMRSAHFLGVDRVITSQRNSCPLTPVVSKASAG---AMEVMDVFATPDLPGFLQAKAQQG---WLVVGTVGCPGPEISQSSKVPITSCLEFVWDRPTLLVLGSEGSGLSQEVFASCQLLLTILPR------RHLPPGLESLNVSVATGILLHSICSQKKGFPVQ-ERGQLLQDS------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IN84-1", "uniprot_id": "MRM1_HUMAN", "id": "Q6IN84-1", "name": "rRNA methyltransferase 1, mitochondrial", "aln": "----------------------------------MALLSTVRGATWGRLVTRHFSHAARHGERPGGEELSRLLLDDLVPTSR----LELLFGMTPCLLALQAARRSVARLLLQAGKAGLQGK-------------------------------------------RAELLRMAEARDIPVLRPRR--------QKLDTMCRYQVHQGVCMEVSP----LRPRPWREAGEASPGDDPQ---------------------------QLWLVLDGIQDPRNFGAVLRSAHFLGVDKVITSRRNSCPLTPVVSKSSAG---AMEVMDVFSTDDLTGFLQTKAQQG---WLVAGTVGCPSTEDPQSSEIPIMSCLEFLWERPTLLVLGNEGSGLSQEVQASCQLLLTILPR------RQLPPGLESLNVSVAAGILLHSICSQRKGFPTEGERRQLLQDPQEPSARSEGLSMAQHPGLSSGPEKERQNEG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25270-1", "uniprot_id": "MRM1_YEAST", "id": "P25270-1", "name": "rRNA methyltransferase 1, mitochondrial", "aln": "------------MTSLTNAVFKRYLAVTPSAHQALKTRIKKKSSSFDKFFPQQSNSRKKQWETLNEDKASWFKRKYAHVHAREQDRAADPYGKKKAHVEKLKEIKNQAKLNQKSHKSKFQNKDIALKLMNDNPIFEYVYGTNSVYAALLNPSRNCHSRLLYHGTIPSKFLQIVDELKVTTELVDK--------HRLNLLTNYGVHNNIALETKP----LQPVEIAYLGDMDTSSAALSIHELGFNNENIPHELPYGTKTDAKKFPLGLYLDEITDPHNIGAIIRSAYFLGVDFIVMSRRNCSPLTPVVSKTSSG---ALELLPIFYVDKPLEFFTKSQEMGGWTFITSHLANATSEKYTVGKTISMHDLNGLCNELPVVLVVGNESQGVRTNLKMRSDFFVEIPFGGIEKGNRAPEPIVDSLNVSVATALLIDNILTCK----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VW14-1", "uniprot_id": "MRM3_DROME", "id": "Q9VW14-1", "name": "rRNA methyltransferase 3, mitochondrial", "aln": "MLCNIFKRSLQANIRNVNNLNVLRLSSSSGPRGEIQDALDIEANLFGNSDLRHEPMNTREALRKNRFAGRKPKVPFASVASRN---LSAPSNPAPRVAPTPAPVIKDNELNLEFVRLTLQDPLTSTLLTTVRSRKRRDKNRQIIVEGRRLIQEALQCG------LKMEVLLFSQKDQLALVKEEVGVAQVETGTKIYKVPQHDLKTWSSLVTPPGLMAIFDRPSDKGLEKNLAEQQR---------------------LGSQPFPITVVCDNIREPNNLGSIIRTCAALPCSQVVVTHGCCDPWESKALRGGCGGQFRVPIRDDVTWDELALTIPPEAADD------CHVFIAETNQRKRENNQTIDYADIKGLGAHNLLIIGGESHGVSEEAYR----FLNLVGGKGKCIYIPLAAGIDSLNVASALTLLLFELRRKLIHQASEKE--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.. :: : . * . .* : : :*. :.* . : :. :: : : :: .: . : : . .. : : : : :*.*:*:::*:. * . :: :: . * . . : ..* : : . . : . . . : . .: :*::*.*. *: :: : . ::****: * :*: .: ", "identical_positions": 21, "similar_positions": 86, "identity": "4.33%" }, { "cls_id": "homologset.agr.SGD:S000005730", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADE8-1", "uniprot_id": "D4ADE8_RAT", "id": "D4ADE8-1", "name": "RNA helicase", "aln": "MSHVAVENALGLDQQFAGLDLNSSDNQTGG-ST-------ASKGRYIPPHLRNREATKGFYDK--------------------------------------------------------------------------------------------------------------------------------DSSGWSSSKDKDAYSSFGSRG------------------DSRGKS-SFFGDRG-----------SGSRGRFDDRG--------------RGDYDGIGGRGDR-----------SGFGKFERG---------------------------------------------------GNSRWCDK-SDEDDWSKPLPPSERLEQELFSG------GNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYADGPGEALRAMK-----ENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGAEIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEEIDKRSFLLDLLNAT-----------------GKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV-----------------------AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLEN-MAFEHHYKGSSR-GRSKSSRFSGGFG---ARDYRQSSGASSSSFSSSRASSSRSGGGGHGS-----SRGFGG--GGYGGFYNS-------DGYGG---NYNSQGVDWWGN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62167-1", "uniprot_id": "DDX3X_MOUSE", "id": "Q62167-1", "name": "ATP-dependent RNA helicase DDX3X", "aln": "MSHVAVENALGLDQQFAGLDLNSSDNQSGG-ST-------ASKGRYIPPHLRNREATKGFYDK--------------------------------------------------------------------------------------------------------------------------------DSSGWSSSKDKDAYSSFGSRG------------------DSRGKS-SFFGDRG-----------SGSRGRFDDRG--------------RGDYDGIGGRGDR-----------SGFGKFERG---------------------------------------------------GNSRWCDK-SDEDDWSKPLPPSERLEQELFSG------GNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYADGPGEALRAMK-----ENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGAEIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEEIDKRSFLLDLLNAT-----------------GKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV-----------------------AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLEN-MAFEHHYKGSSR-GRSKSSRFSGGFG---ARDYRQSSGASSSSFSSSRASSSRSGGGGHGG-----SRGFGG--GGYGGFYNS-------DGYGG---NYNSQGVDWWGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00571-1", "uniprot_id": "DDX3X_HUMAN", "id": "O00571-1", "name": "ATP-dependent RNA helicase DDX3X", "aln": "MSHVAVENALGLDQQFAGLDLNSSDNQSGG-ST-------ASKGRYIPPHLRNREATKGFYDK--------------------------------------------------------------------------------------------------------------------------------DSSGWSSSKDKDAYSSFGSRS------------------DSRGKS-SFFSDRG-----------SGSRGRFDDRG--------------RSDYDGIGSRGDR-----------SGFGKFERG---------------------------------------------------GNSRWCDK-SDEDDWSKPLPPSERLEQELFSG------GNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMK-----ENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNAT-----------------GKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV-----------------------AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLEN-MAYEHHYKGSSR-GRSKSSRFSGGFG---ARDYRQSSGASSSSFSSSRASSSRSGGGGHGS-----SRGFGG--GGYGGFYNS-------DGYGG---NYNSQGVDWWGN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P16381-1", "uniprot_id": "DDX3L_MOUSE", "id": "P16381-1", "name": "Putative ATP-dependent RNA helicase Pl10", "aln": "MSHVAEEDELGLDQQLAGLDLTSRDSQSGG-ST-------ASKGRYIPPHLRNREAAKAFYDK--------------------------------------------------------------------------------------------------------------------------------DGSRWS--KDKDAYSSFGSRS------------------DTRAKS-SFFSDRGG----------SGSRGRFDERG--------------RSDYESVGSRGGR-----------SGFGKFERG---------------------------------------------------GNSRWCDK-ADEDDWSKPLPPSERLEQELFSG------GNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALRAMK-----ENGKYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEEADKRSFLLDLLNAT-----------------GKDSLILVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV-----------------------AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLEN-MAFEHHYKGGSR-GRSKS-RFSGGFG---ARDYRQSSGASSSSFSSGRASNSRSGGGSHGS-----SRGFGG--GSYGGFYNS-------DGYGG---NYSSQGVDWWGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62095-1", "uniprot_id": "DDX3Y_MOUSE", "id": "Q62095-1", "name": "ATP-dependent RNA helicase DDX3Y", "aln": "MSQVAAESTAGLDQQFVGLDLKSSDNQNGGGNT-------ESKGRYIPPHLRNRETSKGVCDK--------------------------------------------------------------------------------------------------------------------------------DSSGWSCSKDKDAYSSFGSR-------------------DSRGKP-NYFSDRG-----------SGSRGRFDDHG--------------RNDYDGIGGR-DR-----------TGFGKFERS---------------------------------------------------GHSRWSDR-SDEDDWSKPLPPSERLEQELFSG------GNTGINFEKYDDIPVEATGNNCPPHIENFSDIEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAMK-----ENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADTVQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEELDKRSFLLDLLNAT-----------------GKDSLTLVFVETKKGADSLENFLFQERYACTSIHGDRSQKDREEALHQFRSGRKPILVATAV-----------------------AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNLNITKDLLDLLVEAKQEVPSWLES-MAYEHHYKGSSR-GRSKS-RFSGGFG---ARDYRQSSGSANAGFNSNRANSSRSSGSSHN-------RGFGG--GGYGGFYNN-------DGYGG---NYNSQAVDWWGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A7A4-1", "uniprot_id": "A0A8I6A7A4_RAT", "id": "A0A8I6A7A4-1", "name": "RNA helicase", "aln": "---MAAENTVGLDQQFAGLDMNS-DNQNGGVST-------ESKGRYIPPHLRNRETSKGVCDK--------------------------------------------------------------------------------------------------------------------------------DNSGWS--KDKDAYSSFGSR-------------------DSRGKP-NYFSDRG-----------SGSRGRFDDPG--------------RSDYDCIASR-DR-----------SGFGKFERS---------------------------------------------------GYSRWGDK-SDEDDWSKPLPPSERLEQELFSG------GNTGINFEKYDDIPVEATGNNCPPHIENFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAMK-----ENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADTVQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEELDKRSFLLDLLNAT-----------------GKDSLTLVFVETKKGADSLENFLFQERYACTSIHGDRSQKDREEALHQFRSGRKPILVATAVCIFYFLVILSDCYFNLISIIFQVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNLNITKDLLDLLVEAKQEVPSWLES-MAYEHHYKGNSR-GRSK--RFSGGFG---ARDYRQSSGYANSGFNNNRANSSRTSGSTHN-------RGFGG--GGYGGFYSN-------EGYGG---NYNSQAVDWWGN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15523-1", "uniprot_id": "DDX3Y_HUMAN", "id": "O15523-1", "name": "ATP-dependent RNA helicase DDX3Y", "aln": "MSHVVVKNDPELDQQLANLDLNS-EKQSGGAST-------ASKGRYIPPHLRNREASKGFHDK--------------------------------------------------------------------------------------------------------------------------------DSSGWSCSKDKDAYSSFGSR-------------------DSRGKP-GYFSERG-----------SGSRGRFDDRG--------------RSDYDGIGNR-ER-----------PGFGRFERS---------------------------------------------------GHSRWCDK-SVEDDWSKPLPPSERLEQELFSG------GNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVK-----ENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGAT-----------------GSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV-----------------------AARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLEN-MAYEHHYKGGSR-GRSKSNRFSGGFG---ARDYRQSSGSSSSGFGASRGSSSRSGGGGYGN-----SRGFGG--GGYGGFYNS-------DGYGG---NYNSQGVDWWGN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QFI7-1", "uniprot_id": "A0A8M9QFI7_DANRE", "id": "A0A8M9QFI7-1", "name": "RNA helicase", "aln": "MSHVVVDGSHGLDQQLAVLDLNSADGQGVG-----------TGRRYIPPHLRNKDASKNAGNAYSSGRQSGYSVAPVQSFSPKQYPQSWHPEGNQRHRQNYPTGWNDFRTGNYLEKADLLLRSSICEGMVVLSALYFCLGSQRFASQELAFYHTYTSGWPDRCASPARTDSSVATDGNEDTASVISWADRCDSPGWDGSRTNGFVNGYHDSR---MNGTANFA-RGPLRNDRGGRG-GFRGNRNGASFN--QPVHNAGYGTYENKDGGWNSVV------NRDAYASFGGRSDRGKSAFFNDRGASSRGRYERGGFGGGT--------------------------------------------GGNSRWVEESRDEEDWSKPMPPNERLEHELFSA------SNTGINFEKYDDIPVEATGTNSPGHIESFHDVDMGEIIMGNITLSRYTRPTPVQKYAIPIIKTKRDLMACAQTGSGKTAAFLLPVLSQIYSEGPGEALQATKASTQQENGKYVRRKQYPISLVLAPTRELALQIYDEARKFAYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDYCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGSRQTMMFSATFPKEIQILARDFLEEYIFLAVGRVGSTSENITQKVVWVEENDKRSFLLDLLNAT-----------------GKDSLTLVFVETKKGADALEDFLYREGYACTSIHGDRSQRDREEALHQFRSGRCPIMVATAV-----------------------AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFYNDKNSNITKDLLDILVEAKQEVPSWLEN-LAYEHQHKSTNR-GRPK--RFSGGFG---ARDYRQMPG-GGNTFGNRGARNT----GGHGG-----NRGFGGNKGGFGSFGGDSYGGTY-GNYGG---NYT--QVDWWGN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BG36-1", "uniprot_id": "A0A8M2BG36_DANRE", "id": "A0A8M2BG36-1", "name": "RNA helicase", "aln": "MSHVAVENVHGLDQQLAALDLSSADVQGV------------TGRRYIPPHLRNKEAAKND--------------------------------------------------------------------------------------------------------APG---------------------------GWDNGRSNGFVNGYHDGRDNRMNGGSSFAGRGPIRSDRGGRG-GFRGKSTG-SYNPIQPMQSAGFG-YDNKDAGGWNVP------KDNAYNSFGGRSDRGKSSFFNDRGSSSRGRYERGGFGG----------------------------------------------GGNSRWVEECRDE-DWSKPLPPNERLEHELFSG------SNTGINFEKYDDIPVEATGHNGPQPIDSFHDLEMGEIIMGNINLSRYTRPTPVQKHAIPIIKSKRDLMACAQTGSGKTAAFLLPVLSQIYTDGPGEALQAAKNSAQ-ENGKYGRRKQYPISLVLAPTRELALQIYDEARKFSYRSHVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDYCNYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGLRQTMMFSATFPKEIQILARDFLEDYIFLAVGRVGSTSENITQKVVWVEENDKRSFLLDLLNATVIPSEVQESTGESVEKPGKDSLTLVFVETKKGADALEDFLYREGYACTSIHGDRSQRDREEALHQFRSGRCPILVATAV-----------------------AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNDKNGNITKDLLDILVEAKQEVPSWLES-LAYEHQHKSSSR-GRSK--RFSGGFG---ARDYRQNSSSGGGGFGGRGGRST----GGHGG-----NRGFGGGKGGFGNFYSS-------DGYGG---NYS--QVDWWGN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHP0-1", "uniprot_id": "DDX3_DROME", "id": "Q9VHP0-1", "name": "ATP-dependent RNA helicase bel", "aln": "MSNAINQNGTGLEQQVAGLDLNGGSADYSGPITSKTSTNSVTGGVYVPPHLRGGGGNNNAADA--------------------------------------------------------------------------------------------------------------------------------ESQGQGQGQGQGFDSRSGNPRQETRDPQQSRGGGGEYRRGGGGGGRGFNRQSGDYGYGSGGGGRRGGGGRFEDNYNGGEFDSRRGGDWNRSGGGGGGGRGFGRGPSYRGGGGGSGSNLNEQTAEDGQAQQQQQPRNDRWQEPERPAGFDGSEGGQSAGGNRSYNNRGERGGGGYNSRWKEGGGSNVDYTKLGARDERLEVELFGV------GNTGINFDKYEDIPVEATGQNVPPNITSFDDVQLTEIIRNNVALARYDKPTPVQKHAIPIIINGRDLMACAQTGSGKTAAFLVPILNQMYELGHVPPPQSTR--------QYSRRKQYPLGLVLAPTRELATQIFEEAKKFAYRSRMRPAVLYGGNNTSEQMRELDRGCHLIVATPGRLEDMITRGKVGLENIRFLVLDEADRMLDMGFEPQIRRIVEQLNMPPTGQRQTLMFSATFPKQIQELASDFLSNYIFLAVGRVGSTSENITQTILWVYEPDKRSYLLDLLSSIRDGPE-----------YTKDSLTLIFVETKKGADSLEEFLYQCNHPVTSIHGDRTQKEREEALRCFRSGDCPILVATAV-----------------------AARGLDIPHVKHVINFDLPSDVEEYVHRIGRTGRMGNLGVATSFFNEKNRNICSDLLELLIETKQEIPSFMED-MSSDRGHGGAKRAGRGGGGRYGGGFG---SRDYRQSSGGGGGGRSGPPPRSGGSGSGGGGGSYRSNGNSYGGNSGGGGYYGGGAGGGSYGGSYGGGSASHSSNAPDWWAQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06634-1", "uniprot_id": "DED1_YEAST", "id": "P06634-1", "name": "ATP-dependent RNA helicase DED1", "aln": "--------MAELSEQVQNLSIND-----------------NNENGYVPPHLRGKPRSARNNSS-------------------------------------------------------------------------------------------------------------------------------------NYNNNNGGYNG------------------------GRGGG-SFFSNNR--------------RGGYGNGG--------------FFGGNNGGSRSNG------------------RS----------------------------------------------------GGRWIDG------KHVPAPRNEKAEIAIFGVPEDPNFQSSGINFDNYDDIPVDASGKDVPEPITEFTSPPLDGLLLENIKLARFTKPTPVQKYSVPIVANGRDLMACAQTGSGKTGGFLFPVLSESFKTGPSPQPESQG--------SFYQRKAYPTAVIMAPTRELATQIFDEAKKFTYRSWVKACVVYGGSPIGNQLREIERGCDLLVATPGRLNDLLERGKISLANVKYLVLDEADRMLDMGFEPQIRHIVEDCDMTPVGERQTLMFSATFPADIQHLARDFLSDYIFLSVGRVGSTSENITQKVLYVENQDKKSALLDLLSAS------------------TDGLTLIFVETKRMADQLTDFLIMQNFRATAIHGDRTQSERERALAAFRSGAATLLVATAV-----------------------AARGLDIPNVTHVINYDLPSDVDDYVHRIGRTGRAGNTGLATAFFNSENSNIVKGLHEILTEANQEVPSFLKDAMMSAPGSRSNSR---------RGGFGRNNNRDYRKAGGASAGGWGSSRSRDN----------------SFRGG-SGWGSDSKS-------SGWGN---SGGSNNSSWW--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.:*. *.:.. . *:*****. . . :. . . .: . * : : ..* : .** : . .*: * :*. .:****::*:****:*:* : * * .* . : :: *: *:*: :******:::**: **************..**.*:*.: : * .: : :** ** .:::******* **::**:**:*** ::..*:*** :*:*:::***.*:******* *:: ***:.* .:*******************:***: *.* * *:*:******* :** ** ***.:****:*************.:::* : **:* ***:*.: .*.* *:*****: ** * :** . *:*****:* :**.** **** .::***** *******.:* ****:*****:::********** ** *:**:*:*..* ** ..* ::* *::**:**:::. : . .* **** ****: . . . . .: * .. * . .:*. . .** ", "identical_positions": 259, "similar_positions": 160, "identity": "26.48%" }, { "cls_id": "homologset.agr.SGD:S000005732", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PTF3-1", "uniprot_id": "E9PTF3_RAT", "id": "E9PTF3-1", "name": "", "aln": "----------------------MAVSRCPRRRLAELTVDEFLASGFESESESELEDIKEPAAKEKKGQRAVANREQRGAHTSPS----LHKGRASEHKDQLSR-------------LKDRDPEFYKFLQENDQSLLNFSDSDTSVEEEEQFHSLPDRLEETSETEE--DGGGDSDTLPRGLQRKKNE---------------PVPVTLAMVERWKQGA-MHHLTPKLFHEVVQAFRAAVATTQGD-----QEAPETCRFQVTDSAVFNALVTFCIRDLCGCLQKLLFAKTVKDSSRMLLPSSSPLWGKLRVDVKTYLSAVVQLVASLAEATVSAAVLQHISSLVPYYLTFPKQCRMLVKRMIVLWSTG-EESLRVLAFLVLIKVCRHKKESFLGPILKQMYIMYVRNCKFTSPSTLPLISFMQRTLTELLALDPSVSYQHAFLYIRQLAVHLRNAMTTGKK--------ETYQSVYNWQYVHCLYLWCRVLSALGSSEV-------LQPLLYPLSQIIIGCIKLLPTARFYPLRMHCVRALTLLSQTVGTFIPVLPFILEIFQQVDFNKRPGRMS-SKPINFSVILKLSSTNLQEKAYRDGLLEQLYDLIMEYLHGQAHSIAFPELVLPTVLQLKSFLRECKVANYCRQVRQLLEKVQENAEHIRSLR--QRVTFSVSDQLAVDAWEKKVREEGTPLTRYYSHWKKLRDREIQLEISGKERLEDLNFPEIKRRKVEDRKDEDRKELKDLFELDSSEGEDSTDFFERGVPGLLESHRGMKEGGQEEEHKEDSDSSSEDGDTDTGVDLS--ELWQLAQGPQDELEDLQLSEED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV70-1", "uniprot_id": "NOC2L_MOUSE", "id": "Q9WV70-1", "name": "Nucleolar complex protein 2 homolog", "aln": "----------------------MAASRAPRRRLEDLSVDEFLASGFESGSESELEG----AAEERRARGAAWNRERRGARTSPGPAGRLRKGRASEHKDQLSR-------------LKDRDPEFYKFLQENDRSLLDFSDSDSSAEEEEPFHSLPDTLEEASETEE--DGGEDSDALPRGLRSKKNE---------------PVPVTLAMVERWRQGS-RHHLTPRLFHEVVQAFRAAVATTQGE-----QEAAETCRFQVADSAVFNALVTFCIRDLCGCLQKLLFGKTPKDSNRLLLPSSSPLWGKLRVDVKSYLSAVVQLAACLAEATVSAAVLQHISSLVPYFLTFPKQCRMLLKRMVVLWSTG-EESLRVLAFLVLIRVCRHKKEAFLGPILKQMYIMYVRNCKFTSPSTLPLISFMQRTLTEMLALDPSVSYQHAFLYIRQLAVHLRNAMTTGKK--------ETHQSVYNWQYVHCLYLWCRVLSTLGSSEI-------LQPLLYPLSQIIIGCIKLLPTARFYPLRMHCVRALTLLSQTIGTFIPVLPFILEIFQQVDFNRRPGRMS-SKPINFSVILKLSSTNLQEKAYRDGLLEQLCDLILEYLHSQAHSIAFPELVLPTVLQLKSFLRECKVANYCRQVRQLLEKVQENARHIESLR--QSATFSVSDRTAVDAWEKQVREEGTPLTRYYGHWKKLRDREIQLEISGKERLEDLNFPEIKRRKVEDRKDEDRKELKDLFELDSSEGEDSTDFFERGVPRLPEAHQGLKED-QEEEDKEEGDSDSEDGDTDTGVDLS--ELWQLAQGAQDELEDLQLSEED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3T9-1", "uniprot_id": "NOC2L_HUMAN", "id": "Q9Y3T9-1", "name": "Nucleolar complex protein 2 homolog", "aln": "----------------------MAAAGSRKRRLAELTVDEFLASGFDSESESESEN--SPQAETREAREAARSPDKPGGSPSAS----RRKGRASEHKDQLSR-------------LKDRDPEFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGDRVPRGLKGKKN----------------SVPVTVAMVERWKQAA-KQRLTPKLFHEVVQAFRAAVATTRGD-----QESAEANKFQVTDSAAFNALVTFCIRDLIGCLQKLLFGKVAKDSSRMLQPSSSPLWGKLRVDIKAYLGSAIQLVSCLSETTVLAAVLRHISVLVPCFLTFPKQCRMLLKRMVIVWSTG-EESLRVLAFLVLSRVCRHKKDTFLGPVLKQMYITYVRNCKFTSPGALPFISFMQWTLTELLALEPGVAYQHAFLYIRQLAIHLRNAMTTRKK--------ETYQSVYNWQYVHCLFLWCRVLSTAGPSEA-------LQPLVYPLAQVIIGCIKLIPTARFYPLRMHCIRALTLLSGSSGAFIPVLPFILEMFQQVDFNRKPGRMS-SKPINFSVILKLSNVNLQEKAYRDGLVEQLYDLTLEYLHSQAHCIGFPELVLPVVLQLKSFLRECKVANYCRQVQQLLGKVQENSAYICSRR--QRVSFGVSEQQAVEAWEKLTREEGTPLTLYYSHWRKLRDREIQLEISGKERLEDLNFPEIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDAEAGLAPGELQQLAQGPEDELEDLQLSEDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIF0-1", "uniprot_id": "NOC2L_DROME", "id": "Q9VIF0-1", "name": "Nucleolar complex protein 2", "aln": "-------------------------MKLATKKIKTLGKSKPDLSKKKPAKDAIRKTKPQTTSETKVTPRNPKQKVAEPVKNGKT----TKKGFKKSHKEELEG-------------LKDIDPEFYDFLKNNDKKLLDFNLLDTDDDDDEEGDEEDKEDTVTKESKDDEDDEEKYHKPSKDLEVASDESDFEVDEEDDAAAGGIQKITLNLLHQWEQQLGQANISIDIVRKVIQAFNSALASISADGADGGENKHNAAAFKVVGAAAFNGVIQLCVIHLQPAIIRLLGVRP----NSSLPLHKHKKWVKVRGCLRYYLTDLIRLVEQVSSPNILGVLLKHLHQMAGMVVPFSALGKTILKRLVVLWSTG-DETVRVLAFLCILKITRKQQATMLNHVLKAMYLAYVRNSKFVSPNTLPGINFMRRSLVEMFALDLNVSYQHVFLYIRQLAIHLRNAVILKKK--------DSFQAVYNWQFINSLRLWADLLGASANKPQ-------LQPLIYPLVTIATGVIRLIPTAQYFPLRFHCLQTLISLAKETNTYVPVLPLIVEVLKSNTFNRKHSAVS-MKPVQFTCVLRLNKGQLAENGFRDEVIEQVCGLLLEYLAHESTSLAFSDLVVPTVMAIKTYLKECRNANYARKLKQLLEKIQESARFIEQQRGKSSVTFDIKDAQAVAAWEQQLRLKRTPLDVYYASWLKTHETKKRRQAAHTDEIN-ADYDVPKLKKLPVKTGVPVRNENGEVELFPSDSEDEGDDGLHLGSDDDDDEDVQEEEEVEVEHPKAKKAKKEKPEKQKPRPATVEDDYDEAGGAVDIVKDLDLNEW-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39744-1", "uniprot_id": "NOC2_YEAST", "id": "P39744-1", "name": "Nucleolar complex protein 2", "aln": "MGKVSKSTKKFQSKHLKHTLDQRRKEKIQKKRIQGRRGNKTDQEKADAAGTREQQQLKKSAKEEVFKDMSVETFFEKGIEIPKENKKLKKKTTKEQSDEDSSSSEEEEDMGQSMAKLAEKDPEFYKYLEENDKDLLDFAGTNPLDGID------------SQDEGEDAERNSNIEEKSEQMELEKEK----------------IELSLKLVRKWKKQL-HDSPSLKLLRNIISAFKVAVNLNKEE-------NIEDYKYAITDEKAFHELMFMVLKDVPQAIQKMAPYKIVKGARTLP---NGGNVSRVSSIVKSHAGSLLILLNDITNTETAALVLHSVNELMPYLLSYRRILKELIKSIVGVWSTTRELETQIASFAFLINTTKEFKKSMLETTLKTTYSTFIKSCRKTNMRSMPLINFQKNSAAELFGIDEVLGYQVGFEYIRQLAIHLRNTMNATTKKSSKINSAEAYKIVYNWQFCHSLDFWSRVLSFACQPEKENGSESPLRQLIYPLVQVTLGVIRLIPTPQFFPLRFYLIKSLIRLSQNSGVFIPIYPLLSEILTSTAFTKAPKKSPNLAAFDFEHNIKCTQAYLNTKIYQEGLSEQFVDLLGDYFALYCKNIAFPELVTPVIISLRRYIKTSTNVKLNKRLSTVVEKLNQNSTFIQEKR--SDVEFGPTNKSEVSRFLNDVAWNKTPLGSYVAVQREVKEEKARLMR-----------------------------------------------------------ESMEEQDKERETEEAKLLNSLESDDDN--------------------EDVEMSDA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: .: . .. : : :* .. .:: . * : *****.:*::**:.**:* :. : :.: : : . . .. :. .: ::: ::.:*.: : :.::::.**. *: : : : :.. .*: :: : : .: .: :: : . :: :: : : * ::.. . :*: : : :.: : ::* :: :*** : :: :* : . :. : ::* ** * :::..: .. ::* *.* : : .*::.:: :.** * ******:****:: .* ::.: *****: :.* :*. :*. *: *:*** : * *:*:**.:::***:: :::* *: ..::*: *:: *:: . *.: . ..:* :: .. * : ::: : **. .* :*: . :.*.:** *.:: :: ::: . .: ::: :: *:::.: .* . * . . *. .: * : : : *** * . : :: : : :: : * : .. . : : :*:::.: ", "identical_positions": 95, "similar_positions": 252, "identity": "11.43%" }, { "cls_id": "homologset.agr.SGD:S000005733", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L8N3-1", "uniprot_id": "A0ABK0L8N3_RAT", "id": "A0ABK0L8N3-1", "name": "DNA-directed RNA polymerase subunit beta", "aln": "-------------MDVLAEEFGSLTP-----EELAAPIPTVEEKWRLLPAFLKVKGLVKQHIDSFNYFINVEIKKIMKANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYTRGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILIQEQLSKNRIIVEADRK-GAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVIIFKAMGVESDQEIVQMIG-TEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWGGGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDN-KVDDRDYYGNKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPK-QRAAQFDVVK--HMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIIKLAGNLGVEDVNLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVSTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIDFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQI-PLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLAKYNE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59470-1", "uniprot_id": "RPC2_MOUSE", "id": "P59470-1", "name": "DNA-directed RNA polymerase III subunit RPC2", "aln": "-------------MDVLAEEFGSLTP-----EQLTAPIPTVEEKWRLLPAFLKVKGLVKQHIDSFNYFINVEIKKIMKANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYTRGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILIQEQLSKNRIIVEADRK-GAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVIIFKAMGVESDQEIVQMIG-TEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWGGGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDN-KVDDRDYYGNKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPK-QRAAQFDVVK--HMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIIKLAGNLGVEDVNLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVSTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIDFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQI-PLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLAKYNE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NW08-1", "uniprot_id": "RPC2_HUMAN", "id": "Q9NW08-1", "name": "DNA-directed RNA polymerase III subunit RPC2", "aln": "-------------MDVLAEEFGNLTP-----EQLAAPIPTVEEKWRLLPAFLKVKGLVKQHIDSFNYFINVEIKKIMKANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYTRGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILIQEQLSKNRIIVEADRK-GAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVIIFKAMGVESDQEIVQMIG-TEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWGGGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDN-KVDDRDYYGNKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPK-QRAAQFDVVK--HMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQI-PLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLSKYNE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QQA2-1", "uniprot_id": "F1QQA2_DANRE", "id": "F1QQA2-1", "name": "DNA-directed RNA polymerase subunit beta", "aln": "---------------MLQEEFGEMSP-----QQLAAPVDTVEEKWKLLPAFLKVKGLVKQHIDSFNYFINVEIKKIMKANEKITSDADPMWYLKYLNIYVGMPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYTRGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPMEFSKLNECPLDPGGYFIVKGQEKVILIQEQLSKNRIIVDQDRK-GTVGASVTSSTHEKKSRTNMIVKQGRFYLKHNTLSEDAPIAIIFKAMGVESDQEIVQMIG-TEEHVMAAFAPSLEECQKAQIFTQTQALRYIGNKVRRQRMWGG-PKKTKMEEARELLASTILTHVPVKEFNFRAKCIYLAVMVRRVILAQGDN-KVDDRDYYGNKRLELAGQLLSLLFEDLFKKFNSELKKIADQIIPK-QRAAQFDVVK--HMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSRLSFISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIIKLAFNLGVEDVNLLCGEELSYPTVFLVFLNGNILGVIRDHQKLVYTFRLMRRAGFINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKNGKPAVKNKHIEELSQGYRTFEDFLHESLVEYLDVNEENDCNIALYEHMISKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQRPMVKTKTIELIDFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLRRYTNQTFDKVMGPMLDAETRKPIWRHSILDADGICSPGEKVENKQVLVNKSMPTVTQT-PLEGSAQPGQPQYREVPVSYKGATDSYIEKVMISSNAEDAFLVKILLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGYPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLIRYGYNYQGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLARYNE-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25167-1", "uniprot_id": "RPC2_DROME", "id": "P25167-1", "name": "DNA-directed RNA polymerase III subunit RPC2", "aln": "MVELKMG-----DHNVEATTWDPGDS-----KDWSVPIKPLTEKWKLVPAFLQVKGLVKQHIDSFNHFINVDIKKIVKANELVTSGADPLFYLKYLDVRVGKPDIDDGFNITKATTPHECRLRDTTYSAPITVDIEYTRGTQRIKRNNLLIGRMPLMLRCSNCALTGKSEFELSKLNECPLDPGGYFVVRGQEKVILIQEQLSWNKMLT-EDFN-GVVQCQVTSSTHEKKSRTLVLSKHGKYYLKHNSMTDDIPIVVIFKALGVVSDQEIQSLIG-IDSKSQNRFGASLIDAYNLKVFTQQRALEYMGSKLVVKRFQSA-TTKTPSEEARELLLTTILAHVPVDNFNLQMKAIYVSMMVRRVMAAELDKTLFDDRDYYGNKRLELAGSLLSMMFEDLFKRMNWELKTIADKNIPK-VKAAQFDVVK--HMRAAQITAGLESAISSGNWTIKRFKMERAGVTQVLSRLSYISALGMMTRVNSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTEVEERPVMIVAFNAGVEDIREVSGNPINNPNVFLVFINGNVLGLTLNHKHLVRNLRYMRRKGRMGSYVSVHTSYTQRCIYIHTDGGRLCRPYVIVENRRPLVKQHHLDELNRGIRKFDDFLLDGLIEYLDVNEENDSFIAWNEDQIEDRTTHLEIEPFTLLGVCAGLVPYPHHNQSPRNTYQCAMGKQAMGMIGYNQKNRIDSLMYNLVYPHAPMVKSKTIELTNFDKLPAGQNATVAVMSYSGYDIEDALILNKASIDRGYGRCLVYKNSKCTVKRYANQTFDRIMGPMKDALTNKVIFKHDVLDTDGIVAPGEQVQNKQIMINKEMPAVTSMNPLQGQS--AQVPYTAVPISYKGPEPSYIERVMVSANAEEDFLIKILLRQTRIPEIGDKFSSRHGQKGVTGLIVEQEDMPFNDFGICPDMIMNPHGFPSRMTVGKTLELLGGKAGLLEGKFHYGTAFGGSKVEDIQAELERHGFNYVGKDFFYSGITGTPLEAYIYSGPVYYQKLKHMVQDKMHARARGPKAVLTRQPTQGRSREGGLRLGEMERDCLISYGASMLIMERLMISSDAFEVDVCRTCGRMAYCSWCHFCQSSANVSKISMPYACKLLFQELTSMNVVPKMILENY---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22276-1", "uniprot_id": "RPC2_YEAST", "id": "P22276-1", "name": "DNA-directed RNA polymerase III subunit RPC2", "aln": "MVAATKRRKTHIHKHVKDEAFDDLLKPVYKGKKLTDEINTAQDKWHLLPAFLKVKGLVKQHLDSFNYFVDTDLKKIIKANQLILSDVDPEFYLKYVDIRVGKK--SSSSTKDYLTPPHECRLRDMTYSAPIYVDIEYTRGRNIIMHKDVEIGRMPIMLRSNKCILYDADESKMAKLNECPLDPGGYFIVNGTEKVILVQEQLSKNRIIVEADEKKGIVQASVTSSTHERKSKTYVITKNGKIYLKHNSIAEEIPIAIVLKACGILSDLEIMQLVCGNDSSYQDIFAVNLEESSKLDIYTQQQALEYIGAKVKTMR----RQKLTILQEGIEAIATTVIAHLTVEALDFREKALYIAMMTRRVVMAMYNPKMIDDRDYVGNKRLELAGQLISLLFEDLFKKFNNDFKLSIDKVLKKPNRAMEYDALLSINVHSNNITSGLNRAISTGNWSLKRFKMERAGVTHVLSRLSYISALGMMTRISSQFEKSRKVSGPRALQPSQFGMLCTADTPEGEACGLVKNLALMTHITTDDEEEPIKKLCYVLGVEDITLIDSASLHLN--YGVYLNGTLIGSIRFPTKFVTQFRHLRRTGKVSEFISIYSNSHQMAVHIATDGGRICRPLIIVSDGQSRVKDIHLRKLLDGELDFDDFLKLGLVEYLDVNEENDSYIALYEKDIVPSMTHLEIEPFTILGAVAGLIPYPHHNQSPRNTYQCAMGKQAIGAIAYNQFKRIDTLLYLMTYPQQPMVKTKTIELIDYDKLPAGQNATVAVMSYSGYDIEDALVLNKSSIDRGFGRCETRRKTTTVLKRYANHTQD-IIGGMRVDENGDPIWQHQSLGPDGLGEVGMKVQSGQIYINKSVPTNSAD-APNPNNVNVQTQYREAPVIYRGPEPSHIDQVMMSVSDNDQALIKVLLRQNRRPELGDKFSSRHGQKGVCGIIVKQEDMPFNDQGIVPDIIMNPHGFPSRMTVGKMIELISGKAGVLNGTLEYGTCFGGSKLEDMSKILVDQGFNYSGKDMLYSGITGECLQAYIFFGPIYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCVIAYGASQLLLERLMISSDAFEVDVCDKCGLMGYSGWCTTCKSAENIIKMTIPYAAKLLFQELLSMNIAPRLRLEDIFQQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. :. : : . :**:*:****:********:****:*::.::***:***: : *..** :****::: ** ... . ..******** ****** ******** : * :: : *****:***..:* * . :::*************:*.* *****:***** *:::. * : * * ..*******:**:* : *:*: **:**::::: **.:::** *: ** ** .:: :. *. .* :. : .::** :**.*:* *: * . * :*. * : :*:::*:.*. :::: *.:* ::*.***: * : .***** *********.*:*::******::* ::* *: : * :* ::*.: ::: :** *: ***:***::*****:* ***:******:*********:.*****:*******:*****:****.:**********************: *: *: :. ****: : . : : *::**.::* ::* :* :** * :..::*: :. : .::* :****:*** :**.. :. *.: *: :* * *:*** .*:**********. ** *. * *********:**. ***:*********************:* *.*** :***:*:* :.**: ****:***** :::************************:***:*:***:*** . :::. .::**:*:* * ::* * . . *::*. *..**: * :*:. *: :**.:*: : . : . * * .*: *:*. *:*::**:* . :: *:*:****.* **:************* *:** ****** * ** **:******:******** :**:.****:*:* :.***.*****::*: * *:** *** . ***** *:***: **:********* **********:********:****:************:*.**** *::*************** ** :.*..** *:*: :: .: :***.******* ***: *:: * ", "identical_positions": 587, "similar_positions": 299, "identity": "50.65%" }, { "cls_id": "homologset.agr.SGD:S000005734", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35992-5", "uniprot_id": "PTP10_DROME", "id": "P35992-5", "name": "Tyrosine-protein phosphatase 10D", "aln": "-----------------------MLYQLSKATTRIRLKRQKAVPQHRWLWS-----------LAFLAAFTLKDVRCADLAISIPNNPGLDDGASYRLDYSPPFGYPEPNTTIASREIGDEIQFSRALPGTKYN-----FWLYYTNFTHHDWLTWTVTITTAPDPPSNLSVQVRSGKNAIILWSPPTQGSYTAFKIKVLGLSEASSSYNRTFQVNDNTFQHSVKELTPGATYQVQAYTIYDGKESVAYTSRNFTTKPNTPGK---FIVWFRN-----------------------ETTLLVLWQPPYPAGIYTHYKVSIEPPDANDSVLYVEKEGEPPGPAQAAFKGLVPGRAYNISVQTMSEDEIS-LPTTAQYRTVPLRPLNVTFDRDFITSNSFRVLWEAPKGISEFDKYQVSVATTRR---------------------------QSTVPRS-NEPVAFFDFRDIAEPGKTFNVIVKTVSGKVTSWPATGDVTLRPLPVRNLRSINDDKTNTMIITWEADPASTQDEYRIVYHELETFN-----------------GDTSTLTTDRTRFTLESLLPGRNYSLSVQAVSKKMESNETSIFVVTRPSSP-----IIEDLKSIRMGLNISWKSDVNSKQEQ----YEVLYSRNGTSDLRTQKTKESRLVIKNLQPGAGYELKVFAVSHDLRSEPHAYFQAVY------PNPPRNMTIETVRSNSVLVHWSPPESGEFTEYSIRYRTDSEQQWVRLP----------SVRSTEADITDMTKGEKYTIQVNTVSFGVESPVPQEVNTTVPP-NPVSNIIQLVDSRNITLEWPKPEGRVESYILKWWPSDNPGRVQTKNVSENKSADDLSTVRVLIGELMPGVQYKFDIQTTSYGILSGITSLYPRTMPLIQSDVVVANGEKEDERD-TITLSYTPTPQSSSKFDIYRFSLGDAEIRDKEKLANDTDRKVTFTGLVPGRLYNITVWTVSGGVASLPIQRQDRLYPEPITQLHATNITDTEISLRWDLPKGEYNDFDIAYLTADN---LLAQNMTTRNEITISDLRPHRNYTFTVVVRSG----------TESSVLRSSSPLSASFTTNEAVPGRVERFHPTDVQPSEINFEWSLPSSEANGVIRQFSIAYTN-INNLTDAGMQDFESEEAFGVIKNLKPGETYVFKIQAKTAIGFGPEREYRQTMPILAPPRPATQVVPTEVYRSSSTIQIRFRKNYFSDQNGQVRMYTIIVAEDDAKNASGLEMPSWLDVQSYSVWLPYQAIDPYYPFENRS--------VEDFTIGTENCDNHKIGYCNGPLKSGTTYRVKVRAFTGADKF-------------------------TDTAYSFPIQTDQDNTSLIVAITVPLTIILVLLVTLLFYKRRRNNCRKTTKDSRANDNMS-LPDSV-------------------IEQNRPILIKNFAEHYRLMSADSDFRFSEEFEELKHVGRDQPCTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINANYVPGHNSPREFIVTQGPLHSTRDDFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPNDT-VPVFYGDIKVQILNDSHYADWVMTEFMLCRGS-------EQRILRHFHFTTWPDFGVPNPPQTLVRFVRAFRDRIG-------AEQRPIVVHCSAGVGRSGTFITLD---RILQQINTSDYVDIFGIVYAMRKERVWMVQTEQQYICIHQCLLAVLEGKENIVGPAREMHDNEGYEGQQVQLDENGDVVATIEGHLSHHDLQQAEAEAIDDENAAILHDDQQPLTSSFTGHHTHMPPTTSMSSFGGGGGGHTNVDAPDRXHSVVNQSDNNNSVVIVLVDNKPSSMICKDSKGGNIDVLESQQQQQQQQQQQPNQGGHNITTISAINGYNTLQHRRKSQLITFSSSSCDIKNSLSHEYINGSNGSAANGPPSSGSGSGSGPGSNRASRANVRLSFAEEDVMILPQNHSQQSNHQDDEVFTRRRSLLEVEIGVEVGEDGELAPHEMEEDLEEEDEDEELY---MHDEFETHIDTKSNNANDDSGGGSYEDSHALHSSLGGSNRNSLEKDDDDIEVDVISTDVSCYDQLLGSSCNTRNGDDDDIATLVGDGDYSTTKLSKASRLSGAGVGGLVVSGGGGGTAIGGGIAVNGGGVLGNGVGSEAGGGIIYANPFMDDEGIAESGM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W4F5-1", "uniprot_id": "Q9W4F5_DROME", "id": "Q9W4F5-1", "name": "protein-tyrosine-phosphatase", "aln": "-----MDCATRKQQQLRAHHQQQQIQIQTHGRKRQQLQKQRHNHHHYYQNSQQQQKHFVWLVVGILTIFLAQHANAADLVINVPN-ASSNANAFYRIDYSPPFGFPEPNTTIPASDIGKDIKFSRALPGTEYN-----FWLYYTNSTHREQLTWTVNITTAPDPPANLSVQLRSSKSAFITWRPPGSGRYSGFRIRVLGLTDLPFERSYSLEGNE-TLQLSAKELTPGGSYQVQAYSVYQGKESVAYTSRNFTTKPNTPGK---FIVWFRN-----------------------ETTLLVLWQPPFPAGIYTHYRVSITPDDAIQSVLYVEREGEPPGPAQAAFKGLVPGREYNISVQTVSEDETSSVPTTARYLTVPERVLNVTFDEAYTTSSSFRVRWEPPRTYSEFDAYQVMLSTSRR---------------------------IFNVPRAANGDSVYFDYPDILEPGRTYEVVVKTIADNVNSWPASGEVTLRPRPVRSLGGFLDDRSNALHISWEPAETGRQDSYRISYHEQTNASE---------VPAPFPVAAESQITTNLTEYTLDSLLAGRRYLIAVQALSKGVASNASDITRYTRPAAP-----LIQELRSIDQGLMLSWRSDVNSRQDR----YEVHYQRNGTREERTMATNETSLTIHYLHPGSGYEVKVHAISHGVRSEPHSYFQAVF------PKPPQNLTLQTVHTNLVVLHWQAPEGSDFSEYVVRYRTDASP-WQRIS----------GLHENEARIKDMHYGERYLVQVNTVSFGVESPHPLELNVTMPP-QPVSNVVPLVDSRNLTLEWPRPDGHVDFYTLKWWPTDEEDRVEFKNVTQLEDLSSPS-VRIPIEDLSPGRQYRFEVQASSNGIRSGTTHLSTRTMPLIQSDVFIANAGHEQGQDETITLSYTPTPADSTRFDIYRFSMGDPTIKDKEKLANDTERKLSFSGLTPGKLYNVTVWTVSGGVASLPVQRLYRLHPLPISDLKAIQVAAREITLHWTAPAGEYTDFELQYLSADEEAPQLLQNVTKNTEITLQGLRPYHNYTFTVVVRSGSIQGTDFADVSVSTLMRSSAPISASYQTLTAPPGKVDYFQPSDVQPGEVTFEWSLEPAEQHGPIDYFRITCQN-ADDAADVSSYEFPVNATQGKIDGLVPGNHYIFRIQAKSALGYGAEREHIQTMPILAPPVPEPSVTPLEVSRTSSTIEISFRQGYFSNAHGMVRSYTIIIAEDVGKNASGLEMPSWQDVQAYTVWLPYQAIEPYNPFLTSNGSRKSSLEAEHFTIGTANCDKHQAGYCNGPLRAGTTYRIKIRAFTDEDKF-------------------------TDTVYSSPITTERSDT-VIVAATVSAVLLVAMVLVVVYCQHRCQLIRRASKLARMQDELAALPEGY-------------------ITPNRPVHVKDFSEHYRIMSADSDFRFSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDR-VAMFYGDIKVQLIIDTHYHDWSISEFMVSRNC-------ESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIG-------TDMRPIIVHCSAGVGRSGTFIALD---RILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEGKEHLLADSLELHANDGYEVTKIYLERQ---------------------------------------------------PQTKMG------------TLPIR-------------ASLAMAEKLDADLMTNKD--------EDEDQEQQQQQQ--------------------------------------------------------------------------------------------------------------------LQLATEVKPKGSNDDEEDEED-DDDDDDDQQP---LNNETTATLSSASCSSS----------THDVHVVL----QEAIEKPKQ--EQERICAGTQSHADTESDNTDSDDDDED----------------------------------GDGKVAKDGAVADEDGWWY-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0AB32TYG0-1", "uniprot_id": "A0AB32TYG0_DANRE", "id": "A0AB32TYG0-1", "name": "protein-tyrosine-phosphatase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMEAHLLSFVK-----------RVNCLSNHDRS-------------------------GDQLISSEFSLIRKKT------------------------------------------------------------------------------ASLKEDYGLTTNAG-----------------------GMKENVKKNRYRDILPYDQTRVCLTPTTSEYQSDYINANFVKGAVRNRTYIATQGPLSSTVVDFWRMIWQHNVKVIIMACREIEMGKKKCEVYWASTS-DTSTLGPFTVSTLEESRPNEEVIVRTLVVNYCD------EARKVSHFQYTAWPDHGIPDMPDGILGMMELARQKQG-------NQTDPVVIHCSAGCGRTGVICAVDYVNDLLLTEQIQEDFNILDLVLELRRQRPSAVQTKEQYGFVFHTVAQMFQKALEMKNMNADTSLYINAVPPKISQKSASLAPAR--------------------------------------------APAKTRN-----------PHLKPR-------------LSLPQSTMNDTYAVINKS--------KVQAPNSAPHSVT-------------------------------------------------------------------------------------------------------------------VHFYDNANSEKTNNSAVYSTVKPKTRPVSAMP---LSPSPIHDRPMPANQRGGLSLKKMESDGYELLPGELRSMNRDSQPHGPPLSRSPSATESQSSTDDDYEYVSSVVKDGSS-------------------------------PFAPGSLGFNSRIKKPKGPREPPAEWSRAER-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P16620-1", "uniprot_id": "PTP69_DROME", "id": "P16620-1", "name": "Tyrosine-protein phosphatase 69D", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALLYRRMSMLLNIILAYIFLCAICVQGSVKQEWAEIGKNVSLECASENE---AVAWKLG-----------------------NQTIN---------KNHTRYKIRTEPLKSND-------DGSENNDSQDFIKYKNVLALLDVNIK-----------DSGNYTCTAQTGQNHSTEFQVRPYLPSKVLQSTPDRIKRKIKQDVMLYCLIE---------------------------MYPQNETTNRNLKWLKDGSQFEFLDTFSSISKLNDTHLNFTLEFTEVYKKENGTYKCTVFDDTG-----------LEITSKEITLFVMEVPQVS------------------------------IDFAKAVGANKIYLNWTVNDGNDPIQKFFITLQEAGTP-----TFTYHKDFINGSHTSYILDHFKPNTT----YFLRIVGKNSIGNGQPTQYPQGITTLSYDP-------IFIPKVETTGSTASTITIGW------NPPPPDLIDYIQYYELIVSESGEVPKVIEEAIYQQNSRNLPYMFDKLK----------TATDYEFRVRACSDLTKTCGPWSENVNGTTMDGVATKPTNLSI-QCHHDNVTRGNSIAINWDVPKTPNGKVVSYLIHLLGNPMSTVDREMWGPKIRRIDEPHHKTLYESVSPNTNYTVTVSAITRHKKNGEPATGSCLMPVSTPDAIGRTMWSKVNLDSKYVLKLYLPKISERNGPICCYRLYLVRINNDNKELPDPE----------------------------------KLNIATYQEVHSDNVTRSSAYIAEMISSKYFR--PEIFLGDEKRFSENNDIIRDNDEICRKCLEGTPFLRKPEIIHIP----------PQGSLSNSDSELPILSEKDNLIKGANLTEHALKILESKLRDKRNAVTSDENPILSAVNPNVPL-HDSSRDVFDGEIDINSNYTGFLEIIVRDR------------NNALMAYSKYFDIITPATEAEPIQSLNNMDYYLSIGVKAG----AVLLGVILVFIVLWVFHHKKTKN------------------------------------------------ELQGEDTLTLRDS----------LSRALFGRRNH-------------------------NHSHFITSGNHKGFDAG-------------------------------------------------------------------------PIHRLDLENAYKNRHKDTDYGFLREYEMLPNRFSDRTTKNSDLKENACKNRYPDIKAYDQTRVKLAVINGLQTTDYINANFVIGYKERKKFICAQGPMESTIDDFWRMIWEQHLEIIVMLTNLEEYNKAKCAKYWPEKVFDTKQFGDILVKFAQERKTGDYIERTLNVSKNKANVGEEEDRRQITQYHYLTWKDFMAPEHPHGIIKFIRQINSVYS-------LQRGPILVHCSAGVGRTGTLVALD---SLIQQLEEEDSVSIYNTVCDLRHQRNFLVQSLKQYIFLYRALLDTGTFGNTDICIDTMASAIESLKRKPNEGKCKLEVEFEK--------------------------------------------LLATADEISKSCSVGENEENNMKNRSQEIIPYDRNRVILTPLPMRENSTYINASFIEGYDNSETFIIAQDPLENTIG---------------------------------------------------------------------------------------------------------DFWRMISEQSVTTLVMISEIGDGPRKCPRYWADDEVQYDH---ILVKYVHSESCPYYTRREFYVTNCKIDDTLKVTQFQYNGWPTVDGEVPEVCRGIIELVDQAYNHYKNNKNSGCRSPLTVHCSLG------TDRSSIFVAMCILVQHLRLEKCVDICATTRKLRSQRTGLINSYAQYEFLHRAIINYSDLHHIAESTLD--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P16621-1", "uniprot_id": "LAR_DROME", "id": "P16621-1", "name": "Tyrosine-protein phosphatase Lar", "aln": "MGLQMTAARPIAALSLLVLSLLTWTHPTIVDAAHPPEIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKVSGTQSRYTVLEQPGGISILRIEPVRAGRDDAPYECVAENGVGDAVSADATLTIYEGDKTPAGFPVITQGPGTRVIEVGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPRYSLKDGFLQIENSREEDQGKYECVAENSMGTEHSKATNLYVKVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHVKWMKGSEDLTPENEMPIGRNVLQLINIQESANYTCIAASTLGQIDSVSVVKVQSLPTAPTDVQISEVTATSVRLEWSYKGPEDLQYYVIQYKPKNANQAFSEISGIITMYYVVRALSPYTEYEFYVIAVNNIGRGPPSAPATCTTGETKMESAPRNVQVRTLSSSTMVITWEPPETPNGQVTGYKVYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQQGVPSQPSNFRATDIGETAVTLQWTKPTHSSENIVHYELYWNDTYANQAHHKRISNSEAYTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGAPPRNITAIATSSTTISLSWLPPPVERSNGRIIYYKVFFVEVGREDDEATTMTLNMTSIVLDELKRWTEYKIWVLAGTSVGDGPRSHPIILRTQEDVPGDPQDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHIHAQELRDEGKGFLNEPFKFDVVDTLEFNVTGLQPDTKYSIQVAALTRKGDGDRSAAIVVKTPGGVPVRPTVSLKIMEREPIVSIELEWERPAQTYGELRGYRLRWGVKDQALKEEMLSGPQMTKKRFDNLERGVEYEFRVAG-SNHIGIGQETVKIFQTPEGTPGGPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFHKKIDHG-LGSERNMTLRKAVFTNLEENTEYIFRVRAYTKQGAGPFSDKLIVETERDMGRAPMSLQAEATSEQTAEIWWEPVTSRGKLLGYKIFYTMTAVEDLDDWQTKTVGLTESADLVNLEKFAQYAVAIAAR-FKNGLGRLSEKVTVRIKPEDVPLNLRAHDVSTHSMTLSWSPPIRLTPVNYKISFDAMKVFVDSQGFSQTQIVPKREIILKHYVKTHTINELSPFTTYNVNVSAIPSDYSYRPPTKITVTTQMAAPQPMVKPDFYGVVNGEEILVILPQASEEYGPISHYYLVVVPEDKSNLHKIPDQFLTDDLLPGRNKPERPNAPYIAAKFPQRSIPFTFHLGSGDDYHNFTNRKLEREKRYRIFVRAVVDTPQKHLYTSSPFSEFLSLDMREAPPGERPHRPDPNWPAEPEVSVNRNKDEPEILWVVLPLMVSTFIVSTALIVLCVVKRRRQPCKTPDQAAVTRPLMAADLGAGPTPSDPVDMRRLNFQTPGMISHPPIPISEFANHIERLKSNDNQKFSQEYESIEP-GQQFTWDNSNLEHNKSKNRYANVTAYDHSRVQLPAVEGVVGSDYINANYCDGYRKHNAYVATQGPLQETFVDFWRMCWELKTATIVMMTRLEERTRIKCDQYWPTRG--TETYGQIFVTITETQELATYSIRTFQLCRQGFN-----DRREIKQLQFTAWPDHGVPDHPAPFLQFLRRCRALTP-------PESGPVIVHCSAGVGRTGCYIVID---SMLERMKHEKIIDIYGHVTCLRAQRNYMVQTEDQYIFIHDAILEAIICGVTEVPARNLHTHLQKLLITEPGETISGMEVEFK--------------------------------------------KLSNVKMDSSKFVTANLPCNKHKNRLVHILPYESSRVYLTPIHGIEGSDYVNASFIDGYRYRSAYIAAQGPVQDAAEDFWR-------------------------------------------------------------------------------------------------------MLWEHNSTIVVMLTKLKEMGREKCFQYWPHERSVRYQY---YVVDPIAEYNMPQYKLREFKVTDARDGSSRTVRQFQFIDWPEQG--VPKSGEGFIDFIGQVHKTKEQFGQDGPITVHCSAG---------VGRSGVFITLSIVLERMQYEGVLDVFQTVRILRSQRPAMVQTEDQYHFCYRAALEYLGSFDNYTN-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJ95-1", "uniprot_id": "Q9VJ95_DROME", "id": "Q9VJ95-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTAATGGGSSGAGGGKTGKHRSRSSARYDDVEKQQRKSRAIVSIPNTIKLS--------------------------------------------------------MLNSGLLSFER-------------IKLEARDEN---------------------------NSLSKTIPNGPIDIR---------------------------------------------------------------------------HFLKLCDLRRKFPVLYKLEFQTAAKVESN-----TCRHALKKNNLEKNQNPKCIPYDYNRVVLEKVGGLQDSDYVNASYVDSLLKPNAYIVTQGPVEETVQAYWRMVWQENISAIVMLTKTFDFAKVMCHQYWPPNMEVHEQYGDIFINIVREEQLANFHIRTFRLYKMNEK-QEVTDERLILQFHYTEWYSHSCP-FSNALLEFRRRVRLVVGNIIKDEDDMRGPILVHCSDGGGRSGVYMSID---ANLELAEEEECFNVFGYLKKLRQSRKGLVENVEQYKFIYDTLEEHIICGKTWFPVSELSDRLKAKARRNSGTKMNEYQAEYD------------------------------------------QICKQTPRFTIGDCAGGHRADNREKNRDVLCVPPDNFRPYLTSFQGNAFTDYINSVFVDGYTKPREYIVTEWPMKHTLG---------------------------------------------------------------------------------------------------------EFWSLVYDQECSAVVVLCQPPSQSQQYPSFWPNKSKMEKYGPVFSVHYVMSKSYTNIKQWEFKINKKIVSLTEMMAGVKAPTRTVQLFQLTCWPMGHKVPSSTNSLVYLMNMVEIWRNKVDYGPVCVVSPD-GRSRAGVYCAANACIEQVIQHGEVDVFQAVKTVRRHRPQLVENMTEYKYCYDLVLHYVLHFLNKKE-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P29461-1", "uniprot_id": "PTP2_YEAST", "id": "P29461-1", "name": "Tyrosine-protein phosphatase 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDRIAQQYRNGKRDNNGNRMASSAISE----------------------KGHIQVNQTRTPGQMPVYRGETINLSNLPQNQIKPCKDLDDVNIRRNNSNRHSKILLLDLCAGPNTNSFLGNTN-------------------------------------AKDITVLSLPLPSTLVKRSNYPFENLLKNYLGSDEKYIEFTKIIKDYDIFIFSDSFSRIS------------------------------------------------SCLKTTFCLIEKFKKFICHFFPSPYLKFFLLEGS-------------------------LNDSKAPSLGKNKKNCILP--------------------------------------------------------------------------KLDLNLNVNLTSRSTLNLRINIPPPND--------SNKIFLQSLKKDLIHYSPNSLQKFFQFNMPADLAPNDTILPNWLKFCSVKENEKVILKKLFNNFETLENFEMQRLEKCLKFKKKPLHQKQLSQKQRGPQSTDDSKLYSLTSLQRQYKSSLKSNIQKNQKLKLIIPK-----NNTSSSPSPLSSDDTIMSPINDYELTEGIQSFTKNRY--------SNILPYEHSRVKLPHSPKPPAVS---EASTTETKTDKSYPMCPVDAKNHSCKPNDYINANYLKLTQINPDFKYIATQAPLPSTMDDFWKVITLNKVKVIISLNS----------------------------------------------------------------DDELNLRKWDIYWNNLSYSNHTIKLQNTWENICNINGCVLRVFQVKKTAPQNDNISQDCDLPHNG------------------------------------------------------------------------------------------------------------DLTSITMAVSEPFIVYQLQYKNWLDSCGVDMNDIIKLHKVKNSLLFNPQSFITSLEKDVCKPDLIDDNNSELHLDTANSSPLLVHCSAGCGRTGVFVTLDFLLSILSPTTNHSNKIDVWN-------------------------MTQDLIFIIVNELRKQRISMVQNLTQYIACYEALLNYFALQKQIKNALPC-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .: . *: . . : . .* : ..: . : .. .: : : : . . : . . : : : * : . *. :: :. . : . . :* : : : : . . . ", "identical_positions": 5, "similar_positions": 51, "identity": "0.23%" }, { "cls_id": "homologset.agr.SGD:S000005735", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6XQN1-1", "uniprot_id": "PNCB_RAT", "id": "Q6XQN1-1", "name": "Nicotinate phosphoribosyltransferase", "aln": "-----------MEMELDD-QGRMVVRPLLTDLYQATMGLGYWRAGRACEEAEFELFFRHCPFGGSFALTAGLQDCIRFLRAFRLRDADVQFLASVLPPDTDPAFFEHLRALDCSRVSVRALPEGSLAFPGVPLLQVSGPLLLVQLLETPLLCLVSYASLVATNAARLRLIAGPDKRLLEMGLRRAQGPDGGFTASIYSYLGGFDSSSNTLAGQLRGVPVAGTLAHSFITSFLGSEVPPDPMLAPASSEGPAVDLPASVNLWLKHVCIYLGLEEREPHLGERAAFVAYALAFPRAFQGLLDSYSVRRSGLPNFLAVALALGELGYRA------VGVRLDSGDLLQQAKEIRGIFRTVGAEFQMPWLEFVPIAVSNNIDEKELAR--LAQKGSEVNVIGIGTNVVTCPKQPSMGCVYKLVSVGGQPRIKLTEESQKETLPGSKAAFRFLVSEGSLLLDLLQLAEEPPPKAGQELRVWLQG--AQEPCTVKPAQVEPLLRLYLQQGQPYEPLPSLEESRAFAQQSLSRLRPAHKQLQNPAVYQVALSEKLRALVDSLSARGAL--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CC86-1", "uniprot_id": "PNCB_MOUSE", "id": "Q8CC86-1", "name": "Nicotinate phosphoribosyltransferase", "aln": "-----------MEMELDS-EGRMVVRPLLTDLYQATMALGYWRAGRACEAAEFELFFRHCPFGGSFALSAGLQDCMRFLRAFRLRDADVQFLASVLPPDTDPAFFEHLRALDCSGVTVRALPEGSLAFPGVPLLQVSGPLLLVQLLETPLLCLVSYASLVATNAARLRLIAGPDKKLLEMGLRRAQGPDGGFTASIYSYLGGFDSSSNTLAGQLRGVPVAGTLAHSFVTSFSGSEVPPDPMLAPASSEGPTVDLPARVNLWLKRVCLYLGLEEQEPHPGERAAFVAYALAFPRAFQGLLDSYSVRRSGLPNFLAVALALGELGYRA------VGVRLDSGDLLQQAKEIRGIFRTAGAQFQMPWLESVPIAVSNNIDESELMR--LAQKGSEVNVIGIGTSVVTCPKQPSMGCVYKLVSVGGQPRIKLTEDPEKQTLPGSKAAFRFLGPDGSLLLDLLQLAEEPPPKAGQELRVWPRG--TQEPCTVKPAQVEPLLRLYLQQGQLCEPLPSLDESRRFAQQSLSLLRPAHKQLQSPAVYPVALSEKLRALVDSLSARGPL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6XQN6-1", "uniprot_id": "PNCB_HUMAN", "id": "Q6XQN6-1", "name": "Nicotinate phosphoribosyltransferase", "aln": "-----------MAAEQDP-EARAAARPLLTDLYQATMALGYWRAGRARDAAEFELFFRRCPFGGAFALAAGLRDCVRFLRAFRLRDADVQFLASVLPPDTDPAFFEHLRALDCSEVTVRALPEGSLAFPGVPLLQVSGPLLVVQLLETPLLCLVSYASLVATNAARLRLIAGPEKRLLEMGLRRAQGPDGGLTASTYSYLGGFDSSSNVLAGQLRGVPVAGTLAHSFVTSFSGSEVPPDPMLAPAAGEGPGVDLAAKAQVWLEQVCAHLGLGVQEPHPGERAAFVAYALAFPRAFQGLLDTYSVWRSGLPNFLAVALALGELGYRA------VGVRLDSGDLLQQAQEIRKVFRAAAAQFQVPWLESVLIVVSNNIDEEALAR--LAQEGSEVNVIGIGTSVVTCPQQPSLGGVYKLVAVGGQPRMKLTEDPEKQTLPGSKAAFRLLGSDGSPLMDMLQLAEEPVPQAGQELRVWPPG--AQEPCTVRPAQVEPLLRLCLQQGQLCEPLPSLAESRALAQLSLSRLSPEHRRLRSPAQYQVVLSERLQALVNSLCAGQSP--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P3H4-1", "uniprot_id": "PNCB_DANRE", "id": "Q6P3H4-1", "name": "Nicotinate phosphoribosyltransferase", "aln": "-----------MATSNEAGSVLNRVPPLLTDLYQ--MAYAYWRAGRHNEPAVFELFFRDNPFGGGFSLFAGLSDCLLFLQNFSFSDDDVQYLRSVLPADTDAGFFSYLKELDCSCVSVSAVPEGSVVFARVPLLEVSGPLAVVQLLETSLLCLVNYASLVCSNAARFRLAAGPRRRLMEMGLRRAQGPDGGLTASRYTYIGGFDLTSNALAGRLYGIPVAGTMAHSYITSFSSLEEVWPQTLKPCGG-GDSIDFICLVKGLLGRVCQLLGSKTNLIREGELAAFLSYAIAYPQNFLPVIDSYSVRCSGLLCFCAVALALFELQYRP------LGVRLDSGDLCRQSLDVRRVFRECSKHFSVPQFESLIIVGTNSISEQSLSE--LNKKDNEIDVVGVGTHLVTCTRQPSLGCVYKLVEVRGRPRMKLSEDPEKSTLPGRKAVYRLLDADGHPQMDVLCLCDEAAPAAGVELQCFSLLGNSTLQCSITPAQVSSLRTQVFSCGQITLPLNSASESRERAQISLQMLNPYHKRLQEPHNYTVALSERLHSLVSDIKKGNSKGSNFLLSN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQX4-1", "uniprot_id": "PNCB_DROME", "id": "Q9VQX4-1", "name": "Nicotinate phosphoribosyltransferase", "aln": "MNDRELGCAGGQFMDRGRMNQNGVVQPLLTDLYQITMAYAYWKSDKTDDTAVFDLFFRNNPFHGEFTIFAGLEECLKFLDSFHYSQSDIEYLKQTLPEGIEHEFFEYLGNLTARDVTLYAIDEGTVAFPRVPIIKIEGPLIIVQLLETTLLTLVNYASLMATNAARYRMVAGKHVKLLEFGLRRAQGPDGGLSASKYSYTGGFDGTSNVLAGKLFNIPVKGTHAHAYITSFSSIGELKTRLIKHKQT-GILEDLLEHAVRHRALLSHLLDVSTEESSEGELAAMVSYAIAFPDGFMALVDTYDVKRSGLLNFSAVALALNDLGYHA------LGIRIDSGDLAYLSCLARETFEKVAERFKVPWFNKLTIVASNDINEDTILS--LNEQGHKIDCFGIGTHLVTCQRQPALGCVYKLVEINGQPRIKLSQDVEKVTMPGNKNAYRLYSADGHALIDLLQKVSEPPPAVGQKVLCRHPFQ-ESKRAYVIPSHVESLYKVYWKSGKICQQLPTLEQVREKVQISLKTLRNDHKRTLNPTPYKVAVSDNLYNFIHDLWLQNAPIGELS---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39683-1", "uniprot_id": "NPT1_YEAST", "id": "P39683-1", "name": "Nicotinate phosphoribosyltransferase", "aln": "------------------MSEPVIKSLLDTDMYKITMHAAVFTN-FPDVTVTYKYTNRSSQLTFNKEAINWLKEQFSYLGNLRFTEEEIEYLKQEIP-YLPSAYIKYISSSNYKLHPEEQISFTSEEIEGKP-THYKLKILVSGSWKDTILYEIPLLSLISEAYFKFVDIDWDYENQLEQAEKKAETLFD--NGIRFSEFG---------TRRRRSLKAQDLIMQGIMKAVNGNPDRNKSLLLGTSN----------ILFAKKYGVKPIGTVAHEWVMGVASISEDYLHANKNAMDCWINTFGAKNAGLALTDTFGTDDFLKSFRPPYSDAYVGVRQDSGDPVEYTKKISHHYHDV---LKLPKFSKIICYSDSLNVEKAITYSHAAKENGMLATFGIGTNFTNDFRK------------KSEPQVKSEP---------LNIVIKLLEVNGN---HAIKISDNLGKNMG------------------DP-----------------ATVKRVKEELGYTERSWSGDNEAHRWT-----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * **:*: * . : . :. * : * : . :* : : ::::* . :* ::.:: . : : : * . . : : : .:* : **:. : . :* . ::*: . .. :: * : : .: . . :. :.:. . : :. . * : * * : ::::.. :** :.. ::. :*:* **** : :. :.:* :. : . *. : ::. : .*:** ... :: ..*::* : . :: :* . : .: * * : : .: * . *: ", "identical_positions": 40, "similar_positions": 127, "identity": "7.04%" }, { "cls_id": "homologset.agr.SGD:S000005736", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62875-1", "uniprot_id": "RPAB5_HUMAN", "id": "P62875-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "aln": "MIIPVRCFTCGKIVGNKWEAYLGLLQA-EYTEGDALDALGLKRYCCRRMLLAHVDLIEKLLNYAPLEK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62876-1", "uniprot_id": "RPAB5_MOUSE", "id": "P62876-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "aln": "MIIPVRCFTCGKIVGNKWEAYLGLLQA-EYTEGDALDALGLKRYCCRRMLLAHVDLIEKLLNYAPLEK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5Y7Y5-1", "uniprot_id": "A0A8I5Y7Y5_RAT", "id": "A0A8I5Y7Y5-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "aln": "MIIPVCCFTCGKIIGNKWEAYLGLLQA-MYTEGDALDTLDLKRYCCRCMLLAHADLIEKLLNYALLEK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VC49-1", "uniprot_id": "RPAB5_DROME", "id": "Q9VC49-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "aln": "MIIPIRCFTCGKVIGNKWESYLGLLQA-EYTEGDALDALGLKRYCCRRMLLGHVDLIEKLLNYAPLEK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22139-1", "uniprot_id": "RPAB5_YEAST", "id": "P22139-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "aln": "MIVPVRCFSCGKVVGDKWESYLNLLQEDELDEGTALSRLGLKRYCCRRMILTHVDLIEKFLRYNPLEKRD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*: **:***::*:***:**.*** ** **. *.******* *:* *.*****:*.* *** ", "identical_positions": 42, "similar_positions": 14, "identity": "60.0%" }, { "cls_id": "homologset.agr.SGD:S000005737", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P58281-1", "uniprot_id": "OPA1_MOUSE", "id": "P58281-1", "name": "Dynamin-like GTPase OPA1, mitochondrial", "aln": "MWRAGRAAVACEVCQSLVKHSSGIQRNVPLQKLHLVSRSIYRSHHPALKLQRPQLRTPFQQFSSLTHLSLHKLKLSPIKYGYQPRRNFWPARLAARLLKLRYIILGSAVGGGYTAKKTFDEWKDMIPDLSDYKWIVPDFIWEIDEYIDLEKIRKALPSSEDLASLAPDL--DKITESLSLLKDFFTAGSPGE-----------TAFRATDH-------GSESDKHYRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELR-KLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTS-MLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEE-ILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPK-GKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQGRLKDTENAIENMIGP-DWKKRWMYWKNRTQEQCVHNETKNELEKMLKVNDEHPAYLASDEITTVRKNLESR-GVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFIDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKVKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2TA68-1", "uniprot_id": "OPA1_RAT", "id": "Q2TA68-1", "name": "Dynamin-like GTPase OPA1, mitochondrial", "aln": "MWRAGRAALACEVCQSLVKHSSGVQRNVPLQKLHLVSRSIYRSHHPALKLQRPQLRTSFQQFSSLTNLSLHKLKLSPTKYGYQPRRNFWPARLAARLLKLRYIILGSAVGGGYTAKKTFDEWKDMIPDLSDYKWIVPDFIWEIDEYIDLEKIRKALPSSEDLANFAPDL--DKIAESLSLLKDFFTAGTPGE-----------TAFRATDH-------GSESDKHYRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELR-KLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTS-MLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEE-ILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQDEFSRFMTEPK-GKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQGRLKDTENAIENMIGP-DWKKRWIYWKNRTQEQCVHNETKNELEKMLKVNDEHPAYLASDEITTVRKNLESR-GVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFIDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKVKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60313-1", "uniprot_id": "OPA1_HUMAN", "id": "O60313-1", "name": "Dynamin-like GTPase OPA1, mitochondrial", "aln": "MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQQFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFDQWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDF--DKIVESLSLLKDFFTSGSPEE-----------TAFRATDR-------GSESDKHFRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELR-KLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTS-MLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEE-ILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPK-GKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGP-DWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESR-GVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5U3A7-1", "uniprot_id": "OPA1_DANRE", "id": "Q5U3A7-1", "name": "Dynamin-like GTPase OPA1, mitochondrial", "aln": "MLRAG-SVVTCIACKGLLPSRMGVKFRVPLQKLHPLSRAIHHRYSANNNPQRPPHCSAARHYTSLSRLPMRPPKSRSGGHGYQQHRTFWVARLAARLLKLRYILLGSAVGGGYTAKKTYDEWKEMLPDMSEYTWIVPDFVWELSENIDLDKLASALPELEEIAKLLPDM--EKIGENFTFLKSLLSSETTGE-----------SALRAPDVPPASAAMADSGDKQFKKSSDKEKVDQLQEELLRTQLKYQRMLERLEKENKELR-KVVLQKDDKGIHQRKVKKSLIDMYSEVLDILSDYDSNYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVAMFKDSSREFDLGKEEDLAALRHEIELRMRKSVKEGQTVSPETISLSVKGPGIQRMVLVDLPGVISTVTTGMAADTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPQGKRTIFVLTKVDLAEKNLASPSRIQQIVEGKLFPMKALGYFAVVTGKGSPNESIDSIKDYEEDFFQNSRLLKDG-MLKAHQVTTKNLSLAVSDCFWKMVRESVEQQADAFKASRFNLETEWKNNYPRLRELDRNELYEKAKNEILDEVISLSQVTPKHWES-ILQKKLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPHKALEVAWETLQEEFARFMAEYK-GKDQDDIFDKLKEAVKDESIKRHKWNERAMDSLRVIQHNALEDRSITDKPQWDAAIQFMEETLQSRLKDTESVIADMVGP-DWKQRWMSWKNRTPEQHTRNETKNELERLLKLHEDHTAYLANDEVTTVRKNLEAR-GVEVDPVLIKDTWHQLFRRHFLQKALLHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLGITANTLRQQLTNTEVRRLEKNVKEVLEDFGEDNEKKVQLITGRRVQLAEDLKKVREIQEKLEAFIEALHKEK----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9N0-1", "uniprot_id": "A1Z9N0_DROME", "id": "A1Z9N0-1", "name": "Dynamin-like GTPase OPA1, mitochondrial", "aln": "MLRIYQNTYRRTARKAVVYSTK--VACCNHSTLCGITSHPRRAQDSGSSSSNGRHRG--HEEFLLAGNPARGWQMPPPSRGYG----MLVVRILRGALKLRYIVLGGAIGGGVSLSKKYEEWKDGLPNFKWLEDAMPQGERWSQFSRNLIEVGSLVKNAIEVDPKLKQLGEDKLSEWRNWFDSRLDDAIEAADYQGVQIVETKDDLKAKTTVAALGITSDESRKKYEKLQS--QVETLQTEIMNVQIKYQKELEKMEKENRELRQQYLILKTNKKTTAKKIKKSLIDMYSEVLDELSGYDTGYTMADHLPRVVVVGDQSSGKTSVLESIAKARIFPRGSGEMMTRAPVKVTLAEGPYHVAQFRDSDREYDLTKESDLQDLRRDVEFRMKASVRGGKTVSNEVIAMTVKGPGLQRMVLVDLPGIISTMTVDMASDTKDSIHQMTKHYMSNPNAIILCIQDGSVDAERSNVTDLVMQCDPLGRRTIFVLTKVDLAEE-LADPDRIRKILSGKLFPMKALGYYAVVTGRGRKDDSIDAIRQYEEDFFKNSKLFHRRGVIMPHQVTSRNLSLAVSDRFWKMVRETIEQQADAFKATRFNLETEWKNNFPRLRESGRDELFDKAKGEILDEVVTLSQISAKKWDD-ALSTKLWEKLSNYVFESIYLPAAQSGSQNSFNTMVDIKLRQWAEQALPAKSVEAGWEALQQEFISLMERSKKAQDHDGIFDQLKSAVVDEAIRRHSWEDKAIDMLRVIQLNTLEDRFVHDKQEWDSAVKFLESSVNAKLVQTEETLAQMFGP-GQMRRITHWQYLTQDQQKRRSVKNELDKILKNDTKHLPTLTHDELTTVRKNLQRD-NVDVDTDYIRQTWFPVYRKHFLQQALQRAKDCRKAYYLYTQQGAECEISCSDVVLFWRIQQVIKITGNALRQQVINREARRLDKEIKAVLDEFSDDEEKKGYLLTGKRVLLAEELIKVRQIQEKLEEFINSLNQEK----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32266-1", "uniprot_id": "MGM1_YEAST", "id": "P32266-1", "name": "Dynamin-like GTPase MGM1, mitochondrial", "aln": "---------------------------MNASPVRLLILRRQLATHPAILYSSPYIKSPLVHLHSRMSNVHRSAHANALSFVITRRSISHFPKIISKIIRLPIYVGGGMAAAGSYIAYKMEEASSFT--------------------------KDKLDRIKDLGESMKEK-----------FNKMFSGDKSQD--------------------------GGHGNDGTVPTATLIAATSLDDDESKRQGDPKDDDDEDDDDEDDEN--------DSVDTTQDEMLNLTKQMIEIRTILNKVDSSS-AHLTLPSIVVIGSQSSGKSSVLESIVGREFLPKGS-NMVTRRPIELTLVNTPNSNNVTADFP-SMRLYNIKDFKEVKR-MLMELNMAVPTSEAVSEEPIQLTIKSSRVPDLSLVDLPGYIQVEAADQPIELKTKIRDLCEKYLTAPN-IILAISAADVDLANSSALKASKAADPKGLRTIGVITKLDLVDP-----EKARSILNNKKYPLS-MGYVGVITKTPSSINRKHLGLFGEAPSSSLSGIFSKG---QHGQSSGEENTNGLKQIVSHQFEKAYFKENKKYFTNCQVSTKKLREKLIKILEISMSNALEPTSTLIQQELDDTSYLFKVEFNDRHLTPKSYLLNNIDVLKLGIKEFQEKFHRNELKSILRAELDQKVLDVLATRYWKD--DNLQDLSSSKLESDTDMLYWHKKLELASSGLTKMGIGRLSTMLTTNAILKELDNILESTQLKNHELIKDLVSNTAINVLNSKYYSTADQVENCIKPFKYEIDLEERDWSLARQHSINLIKEELRQCNSRYQAIKNAVGSKKLANVMGYLENESNLQKETLGMSKLLLERGSEAIFLDKRCKVLSFRLKMLKNKCHSTIEKDRCPEVFLSAVSDKLTSTAVLFLNVELLSDFFYNFPIELDRRLTLLG-DEQVEMFAKEDPKISRHIELQKRKELLELALEKIDSILVFKKSYKGVSKNL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . . . : : . :: ::* : *. ..* . :: .. . : :: : :.. : .. . . *: : . * . : :. :.:: : . :. :. .* . *: *. *:. ** :**:*.**:**:**** *. .::*:** :*:** *:::** : * * . * : .*: ::: : :.:. * . :** * * :.:*.. : : ****** *.. : . . : * .* .: : *: ** ***.*. ..** .* . . ** * *** *:**:**.: .: :.*:..* :*:. :** .*:* : . * . * :: * : .: : .:.: . : ..:: :: . : :. .: ::: :: * . .: : :. * :*: * : .::. * . : . *:: :. . ::: : :* * . . *. : : : **: : . . :: ...: . .* * . : *: :: . : .: * . . ::.: .* . : : . * . * . *:** : . : .:::.* *: .:: :. : . . :: : * : : * :*.* ::: : *. :: . .: ::. * :. * : : . :: :* * ::: * *::: * ", "identical_positions": 117, "similar_positions": 280, "identity": "11.75%" }, { "cls_id": "homologset.agr.SGD:S000005738", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52287-1", "uniprot_id": "GBB3_RAT", "id": "P52287-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3", "aln": "--------------------------------------------------MGEMEQLKQEAEQLKKQIADARKACADITLAELVSGLEVVGR--VQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYSLKSR--EGNVKVSRELSAHTGYLSCCRFLD-DNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSP------DYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAY--------------------------SHESII---------CGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVG----VLSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61011-1", "uniprot_id": "GBB3_MOUSE", "id": "Q61011-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3", "aln": "--------------------------------------------------MGEMEQLRQEAEQLKKQIADARKACADITLAELVSGLEVVGR--VQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSR--EGNVKVSRELSAHTGYLSCCRFLD-DNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSP------DYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAY--------------------------SQESII---------CGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVG----ILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16520-1", "uniprot_id": "GBB3_HUMAN", "id": "P16520-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3", "aln": "--------------------------------------------------MGEMEQLRQEAEQLKKQIADARKACADVTLAELVSGLEVVGR--VQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSR--EGNVKVSRELSAHTGYLSCCRFLD-DNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSP------DFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICF--------------------------SHESII---------CGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVG----ILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DH55-1", "uniprot_id": "Q6DH55_DANRE", "id": "Q6DH55-1", "name": "", "aln": "--------------------------------------------------MGEMEQLRKEAEKLKDDITAARKTVQDLTLQDHVAGTAVVGR--VQLKTRKTLRGHLAKIYAMHWGTDSKLCVSASQDGKLIVWDSYTTNKVHAIPLKSSWVMTCSYAPSGNMVACGGLDNMCSIYNLKAK--DGNVKVMRELAAHTGYLSCCRFLS-DSEIITSSGDCTCVLWDIETGSQKTVFAGHLGDCMSLAVSP------DFNTFISGACDFTAKLWDIREGQCRQTFGGHESDINAIGFFPNGNAVITGSDDASCKLYDLRSDQELITY--------------------------QDSSIM---------CGVTSIAPSLSGRLILAGYDDFNCNIWDSLKSERVG----VLSGHDNRVSCIGVTPDGMACCTGSWDSFLKIWN----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P62873-1", "uniprot_id": "GBB1_HUMAN", "id": "P62873-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1", "aln": "--------------------------------------------------MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGR--IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR--EGNVRVSRELAGHTGYLSCCRFLD-DNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAP------DTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY--------------------------SHDNII---------CGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAG----VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54311-1", "uniprot_id": "GBB1_RAT", "id": "P54311-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1", "aln": "--------------------------------------------------MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGR--IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR--EGNVRVSRELAGHTGYLSCCRFLD-DNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAP------DTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY--------------------------SHDNII---------CGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAG----VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62874-1", "uniprot_id": "GBB1_MOUSE", "id": "P62874-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1", "aln": "--------------------------------------------------MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGR--IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR--EGNVRVSRELAGHTGYLSCCRFLD-DNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAP------DTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY--------------------------SHDNII---------CGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAG----VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PH57-1", "uniprot_id": "GBB1_DANRE", "id": "Q6PH57-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1", "aln": "--------------------------------------------------MSELDQLRQEAEQLKNQIRDARKACADATLSQITANIDPVGR--IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR--EGNVRVSRELAGHTGYLSCCRFLD-DNQIVTSSGDTTCALWDIETGQQTTTFAGHTGDVMSLSLAP------DTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMVY--------------------------SHDNII---------CGITSVAFSKSGRLLLAGYDDFNCNVWDALKADRAG----VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P62880-1", "uniprot_id": "GBB2_MOUSE", "id": "P62880-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2", "aln": "--------------------------------------------------MSELEQLRQEAEQLRNQIRDARKACGDSTLTQITAGLDPVGR--IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTR--EGNVRVSRELPGHTGYLSCCRFLD-DNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAP------DGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMY--------------------------SHDNII---------CGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAG----VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62879-1", "uniprot_id": "GBB2_HUMAN", "id": "P62879-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2", "aln": "--------------------------------------------------MSELEQLRQEAEQLRNQIRDARKACGDSTLTQITAGLDPVGR--IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTR--EGNVRVSRELPGHTGYLSCCRFLD-DNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAP------DGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMY--------------------------SHDNII---------CGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAG----VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54313-1", "uniprot_id": "GBB2_RAT", "id": "P54313-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2", "aln": "--------------------------------------------------MSELEQLRQEAEQLRNQIRDARKACGDSTLTQITAGLDPVGR--IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTR--EGNVRVSRELPGHTGYLSCCRFLD-DNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAP------DGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMY--------------------------SHDNII---------CGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAG----VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2BCL1-1", "uniprot_id": "A0A8M2BCL1_DANRE", "id": "A0A8M2BCL1-1", "name": "", "aln": "--------------------------------------------------MSELEQLRQEAEQLRNQIRDARKACGDSTLTQITAGLDPVGR--IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKIHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTR--EGNVRVSRELPGHTGYLSCCRFID-DNQIITSSGDTTCALWDIETGQQTTLFSGHSGDVMSLSLAP------DSRTFISGACDASIKLWDIRDSMCRQTFTGHESDINAACFFPSGSAFATGSDDATCRLFDLRADQELCLY--------------------------SHDNII---------CGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGERAGKHTGVLAGHDNRVSCLGVTDDGMAVCTGSWDSFLKIWN----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P29387-1", "uniprot_id": "GBB4_MOUSE", "id": "P29387-1", "name": "Guanine nucleotide-binding protein subunit beta-4", "aln": "--------------------------------------------------MSELEQLRQEAEQLRNQIQDARKACNDATLVQITSNMDSVGR--IQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR--EGNVRVSRELPGHTGYLSCCRFLD-DGQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSP------DLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELLLY--------------------------SHDNII---------CGITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRSG----VLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35353-1", "uniprot_id": "GBB4_RAT", "id": "O35353-1", "name": "Guanine nucleotide-binding protein subunit beta-4", "aln": "--------------------------------------------------MSELEQLRQEAEQLRNQIQDARKACNDATLVQITSNMDSVGR--IQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR--EGNVRVSRELPGHTGYLSCCRFLD-DGQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSP------DLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELLLY--------------------------SHDNII---------CGITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRAG----VLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HAV0-1", "uniprot_id": "GBB4_HUMAN", "id": "Q9HAV0-1", "name": "Guanine nucleotide-binding protein subunit beta-4", "aln": "--------------------------------------------------MSELEQLRQEAEQLRNQIQDARKACNDATLVQITSNMDSVGR--IQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR--EGNVRVSRELPGHTGYLSCCRFLD-DSQIVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSP------DMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLY--------------------------SHDNII---------CGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAG----VLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P26308-1", "uniprot_id": "GBB1_DROME", "id": "P26308-1", "name": "Guanine nucleotide-binding protein subunit beta-1", "aln": "--------------------------------------------------MNELDSLRQEAESLKNAIRDARKAACDTSLLQAATSLEPIGR--IQMRTRRTLRGHLAKIYAMHWGNDSRNLVSASQDGKLIVWDSHTTNKVHAIPLRSSWVMTCAYAPSGSYVACGGLDNMCSIYNLKTR--EGNVRVSRELPGHGGYLSCCRFLD-DNQIVTSSGDMSCGLWDIETGLQVTSFLGHTGDVMALSLAP------QCKTFVSGACDASAKLWDIREGVCKQTFPGHESDINAVTFFPNGQAFATGSDDATCRLFDIRADQELAMY--------------------------SHDNII---------CGITSVAFSKSGRLLLAGYDDFNCNVWDTMKAERSG----ILAGHDNRVSCLGVTENGMAVATGSWDSFLRVWN----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P62881-1", "uniprot_id": "GNB5_MOUSE", "id": "P62881-1", "name": "Guanine nucleotide-binding protein subunit beta-5", "aln": "MCDQTFLVNVFGSCDKCFKQRALRPVFKKSQQLNYCSTCAEIMATDGLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQ--FVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPS----ETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIY--------------------------SKESII---------FGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVS----ILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62882-1", "uniprot_id": "GNB5_RAT", "id": "P62882-1", "name": "Guanine nucleotide-binding protein subunit beta-5", "aln": "------------------------------------------MATDGLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQ--FVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPS----ETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIY--------------------------SKESII---------FGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVS----ILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14775-1", "uniprot_id": "GNB5_HUMAN", "id": "O14775-1", "name": "Guanine nucleotide-binding protein subunit beta-5", "aln": "MCDQTFLVNVFGSCDKCFKQRALRPVFKKSQQLSYCSTCAEIMATEGLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQ--FVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPS----ETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIY--------------------------SKESII---------FGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVS----ILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L271-1", "uniprot_id": "GNB5A_DANRE", "id": "A1L271-1", "name": "Guanine nucleotide-binding protein subunit beta-5a", "aln": "----------------------------------------MAAQEEPAQPGDSLATLKSESDTLKSKLEEERAKLHDVELHQVAEKIEALGQ--FVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDAFTTNKEHAVTMPCTWVMACAYAPSGCAVACGGLDNKCSVYPLSLDKNENLAAKKKSVAMHTNYLSACCFTNSDMQILTSSGDGTCALWDVESGQMLQSFHGHAADVLCLDLAPS----ETGNTFVSGGCDKKACVWDMRTGQCVQSFESHDSDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIY--------------------------SKESII---------FGASSVDFSLSGRLLFGGYNDYTINVWDVLKGARVS----ILFGHENRVSTLRVSPDGTAFCSGSWDHTLRIWA----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6PBY0-1", "uniprot_id": "GNB5B_DANRE", "id": "Q6PBY0-1", "name": "Guanine nucleotide-binding protein subunit beta-5b", "aln": "MCDQTFLAITFGPCDKCSENKPLMNIYLKNEPINYCSLCVEMMACQGLAKGETVQSLKAESESLKAKLEEERAKLHDVELHQVAEKMEALGQ--FVMKTRRTLKGHGNKVLCMDWCRDKRRIVSSSQDGKVIVWDAYTTNKEHAVTMPCTWVMACAYAPSGCAVACGGLDNKCSVYPLSLDKNENLASKKKSVAMHTNYLSSCSFTKSDMQILTSSGDGTCALWDVESGQLLQSFHGHSADVLSLDLAPS----ETGSTFVSGGCDKKANVWDMRSGQNVQSFETHDSDINSVKYYPSGDAFASGSDDATCRLYDLRADREVAIY--------------------------SKDSII---------FGASSVDFSLSGRLLFAGYNDYNINVWDVLKGTRVA----ILFGHENRVSTVRVSPDGTAFCSGSWDNTLRIWA----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3J1-1", "uniprot_id": "Q9W3J1_DROME", "id": "Q9W3J1-1", "name": "", "aln": "-----------------------------------MSEAAVPASNANANATEKMASLVREAENLKTKLEEERQKLNDVNLSNIAERLEQIAY--VNIKPRKVLKGHQAKVLCTDWSPDKRHIISSSQDGRLIIWDAFTTNKEHAVTMPTTWIMACAYAPSGNFVACGGLDNKVTVYPITSD--EEMAAKKRTVGTHTSYMSCCIYPNSDQQILTGSGDSTCALWDVESGQLLQSFHGHSGDVMAIDLAPN----ETGNTFVSGSCDRMAFIWDMRSGHVVQSFEGHQSDVNSVKFHPCGDAIATGSDDSSCRLYDMRADREVAVF--------------------------AKESII---------FGVNSVDFSVSGRLLFAGYNDYTVNLWDTLKSERVC----LLYGHENKVSCVQVSPDGTALSTGSWDYTIRVWA----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P29829-1", "uniprot_id": "GBB2_DROME", "id": "P29829-1", "name": "Guanine nucleotide-binding protein subunit beta-2", "aln": "----------------------------------------------MPKIDPETQKLYDEINGMIQKFKDDQKSKADCTLADKCGDMGDVPK--IRFSSKKILKGHINKVNSVHFAGDSRHCVTGSLDGKLIIWDTWTANKVQIIPLRSAWVMTVAFSPSGNFVACGGMDNQCTVYDVNNRDASGVAKMVKELMGYEGFLSSCRFLD-DGHLITGSGDMKICHWDLEKGVKTMDFNGHAGDIAGLSLSP------DMKTYITGSVDKTAKLWDVREEGHKQMFFGHDMDVSSVCYHPSGFGFASCSEDQTARMYDLRADQQIAQY--------------------------EPPQKN---------TGFTSCALSTSGRYLMCGGIEGNVHSWDTMKQRHTG----TLSGHENRITCISLCPNGMCLASTSWDQQVRLWL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P18851-1", "uniprot_id": "GBB_YEAST", "id": "P18851-1", "name": "Guanine nucleotide-binding protein subunit beta", "aln": "---------------MAAHQMDSITYSNNVTQQYIQPQSLQDISAVEDEIQNKIEAARQESKQLHAQINKAKHKIQDASLFQMANKVTSLTKNKINLKPNIVLKGHNNKISDFRWSRDSKRILSASQDGFMLIWDSASGLKQNAIPLDSQWVLSCAISPSSTLVASAGLNNNCTIYRVSKE-NRVAQNVASIFKGHTCYISDIEFTD-NAHILTASGDMTCALWDIPKAKRVREYSDHLGDVLALAIPEEPNSENSSNTFASCGSDGYTYIWDSRSPSAVQSFYVNDSDINALRFFKDGMSIVAGSDNGAINMYDLRSDCSIATFSLFRGYEERTPTPTYMAANMEYNTAQSPQTLKSTSSSYLDNQGVVSLDFSASGRLMYSCYTDIGCVVWDVLKGEIVG----KLEGHGGRVTGVRSSPDGLAVCTGSWDSTMKIWSPGYQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : : : * * : : . : .. *:** *: : *.: ::.* ** :::**: : * : :.: *::: : :**. :*..*::* ::* :. . : ::* : . : .::*.*** . **: .. : .* .* : :. : : . * :** * * * : *:.: :. * .. : *:: : .::*:*:* .: : * * * *** : : ** :* * ** .::: : :* . .: *** :::* ", "identical_positions": 59, "similar_positions": 102, "identity": "13.29%" }, { "cls_id": "homologset.agr.SGD:S000005742", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O95153-1", "uniprot_id": "RIMB1_HUMAN", "id": "O95153-1", "name": "Peripheral-type benzodiazepine receptor-associated protein 1", "aln": "MEQLTTLPRPGDPGAMEPWALPTWHSWTPGRGGEPSSAAPSIADTPPAALQLQELRSEESSKPKGDGSSRPVGGTDPEGAEACLPSLGQQASSSGPACQRPEDEEVEAFLKAKLNMSFGDRPNLELLRALGELRQRCAILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERARKLQETNLRVVSAPLPRPGTSLELCRKALARQRARDLSETASALLAKDKQIAALQRECRELQARLTLVGKEGPQWLHVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPALQARAGAPAPGAPGEATPQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEARKKQRRCEELELQLRQAQNENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSALRKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQREHEGAVQLLESTLDSMQARVRELEEQCRSQTEQFSLLAQELQAFRLHPGPLDLLTSALDCGSLGDCPPPPCCCSIPQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKKAESLSNSSHSESIHNSPKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLARYSYNPFEGPNENPEAELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSDDDLLTSLPPELADLSHSSGPELSFLSVGGGGSSSGGQSSVGRSQPRPEEEDAGDELSLSPSPEGLGEPPAVPYPRRLVVLKQLAHSVVLAWEPPPEQVELHGFHICVNGELRQALGPGAPPKAVLENLDLWAGPLHISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEITWVPGNSNLAHAIYLNGEECPPASPSTYWATFCHLRPGTPYQAQVEAQLPPQGPWEPGWERLEQRAATLQFTTLPAGPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYAIYADGQKIMEVASPTAGSVLVELSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAPASLPARVSCPSPHPSPEARAPLASASPGPGDPSSPLQHPAPLGTQEPPGAPPASPSREMAKGSHEDPPAPCSQEEAGAAVLGTSEERTASTSTLGEKDPGPAAPSLAKQEAEWTAGEACPASSSTQGARAQQAPNTEMCQGGDPGSGLRPRAEKEDTAELGVHLVNSLVDHGRNSDLSDIQEEEEEEEEEEEEELGSRTCSFQKQVAGNSIRENGAKSQPDPFCETDSDEEILEQILELPLQQFCSKKLFSIPEEEEEEEEDEEEEKSGAGCSSRDPGPPEPALLGLGCDSGQPRRPGQCPLSPESSRAGDCLEDMPGLVGGSSRRRGGGSPEKPPSRRRPPDPREHCSRLLSNNGPQASGRLGPTRERGGLPVIEGPRTGLEASGRGRLGPSRRCSRGRALEPGLASCLSPKCLEISIEYDSEDEQEAGSGGISITSSCYPGDGEAWGTATVGRPRGPPKANSGPKPYPRLPAWEKGEPERRGRSATGRAKEPLSRATETGEARGQDGSGRRGPQKRGVRVLRPSTAELVPARSPSETLAYQHLPVRIFVALFDYDPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRTGYIPCNMVAEVAVDSPAGRQQLLQRGYLSPDILLEGSGNGPFVYSTAHTTGPPPKPRRSKKAESEGPAQPCPGPPKLVPSADLKAPHSMVAAFDYNPQESSPNMDVEAELPFRAGDVITVFGGMDDDGFYYGELNGQRGLVPSNFLEGPGPEAGGLDREPRTPQAESQRTRRRRVQC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12234-1", "uniprot_id": "RUD3_YEAST", "id": "Q12234-1", "name": "GRIP domain-containing protein RUD3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKNKKKTGKKAKSHPHVEDVDETVNKPEEIINSVN-----------VTVPPKMSTDPEADG------------------------IVASPDDEG---KDLSEGVDKQKVNDGLTVDTIN--------PLEDKKAGDEMKELREEIERLKLELSHKKDQETPNEDFKNELANVIKERDEFKTQYDTLLSKISSMKSIFNKMKEAQK-------QLEEVQEQLTEYESQNLKLKKKLEATKTENS----ELQSTIVTLNTELENLEKEQESTEEVF-------------------------------------------------------------------------------------------------------------LEYESRIEALEDEKHDIIEKHSKELN-------------------TYRKEKDQLNLQVQELMIILENNKQD-----------------------------------ISDLRTE------------------------------------------------------------------------------------------RDELRQALESHEKEKAVLKNS---LNDLELKIEEVDNKREEEARERDQEVKSLRSQLDTEIETHNN---------------------------------------------------------------------DTEALESMKKQLEAMKEDASMKEKYEEESK---------------------------------QHILQIGKLRHEAIILN-----------EHLTKALAMLKKSSDSE--SVDKELISNLLISFVSIPRADP--------------------------------------------------------------------------------------------------------------------------------------------------------------RKFEVLELLSNFLNWDEDKKQQAG--------LISNNESKNSSAVSRTESFVS-----------------------LWTNYLEKESEKD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . .**:. . **.*.*. :.:.:. : :: :.:**. ...* :. *:..*:.* : ** .*:* :.* :: : *: ::* :* .* ** .**. . :.*:: * * :::.:* .* :***. : : * **:.*::.::::*:*. : : *:.: .* * :.: :*:: :: *:. *:**: ::::.:.:**:: .* * * :: *.:* ** :. .:: .: . . .: : :* * . * : * * .:* ::** . ..****** . ****:* . *.:.:: : .: ..:. . * : . : :::..*. : .* . * * **.:. : * .. *:*:::.. ::::: * :.:::: :*:** .: * . * : ** * ..* *: :: :: .: : :*::::: * ::.*. ::..* *:.:.* . *:: *:*.*:: ", "identical_positions": 107, "similar_positions": 221, "identity": "5.76%" }, { "cls_id": "homologset.agr.SGD:S000005743", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFT1-1", "uniprot_id": "D3ZFT1_RAT", "id": "D3ZFT1-1", "name": "Replication factor C subunit 1", "aln": "--MDIRKFFGVISSGKKPVNETVKKNEKTKPSEGTVKGKKGVKEAKVNNPCKEDASRPKQHNKKKRIIYDSDSESEETVQVKNAKKKSEKLPVSCKPGKISRKDPVTYISETDEDDDFLCKKAASKSKENGVSTNSYLGASNVKKNEENTKTKSKPLSPIKLTPTSVLDYFGTESVQRSGKKMVASKKKESSQTPDDSRLNDEAIAKQLQLDEDAELERQLHEDEEFARTLALLDEEPKTKKARKDSEEGE-SFSPAKAELSKAAKQKSPA--NAEHFSIGRKTYSPAKYGKGRGSEGTKQPCRS-AHQKEACSSLKASSKLALMKAQEENSYKETELLAAKR-ESAIEPKGEKTTPRKTKGSPTKRESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLTFVITGVLESIEREEAKSLIERYGGKVTGNVSKKTSYLVMGRDSGQSKSDKAAALGTKILDEDGLLDLIRTMPG---------KKSKYEIAAEAEMKKEKSKLERTPQKNDQGKRKLSPTKRELEPKKSKLTPLKHSPRKAVKEEERVCPRGLDAKEPHGSHSA--------------SREECLLWVDKYKPTSLKNIIGQQGDQSCANKLLRWLRNWHKSSPEEKKHAAKFGKVASKDDGSSFKAALLSGPPGVGKTTTASLVCQELGYSYVELNASDTRSKNSLKAIVAESLNNTSIKGFYTSGASPS--VSARHALIMDEVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIKSAMLSIAFKEGLKIPPPAMNEIILGANQDVRQVLHNLSMWCAQSKVLTYDQAKADSQRAKKDIRLGPFDVTRKVFAAGEETAHMS----LMDKSDLFFHDYSIAPLFVQENYLHVKPVAAGGDMKKHLMLLSRAADSICDGDLVDNQIRS-KQNWSLLPTQAIYASVVPGELMRGYMSQFPSFPSWLGKHSSTGKHDRTVQDLSLHMSLRTYSSKRTVNMDYLSHIRDALVRPLTSQGVEGVQRVVTLMDTYYLVKEDFDNIMEVSSWGGKP-STFSKLDPKVKAAFTRAYNKEAHLTPYSLQVVKASRPSIGPALDSEYNEESQEDA-------TQSDEKEQDALETDAMIKKKTRSSKPSKSEKEKESKKGKGKNSKK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35601-1", "uniprot_id": "RFC1_MOUSE", "id": "P35601-1", "name": "Replication factor C subunit 1", "aln": "--MDIRKFFGVISSGKKPVNETVK-NEKTKASEGTVKGKKGVKEAKVNNSGKEDASKPKQHSKKKRIIYDSDSESEETVQVKNAKKKSEKLSLSYKPGKVSQKDPVTYVSETDEDDDFVCKKAASKSKENGVSTNSYLGTSNVKKNEENVKTKNKPLSPIKLTPTSVLDYFGTESVQRSGKKMVTSKRKESSQNTEDSRLNDEAIAKQLQLDEDAELERQLHEDEEFARTLALLDEEPKIKKARKDSEEGEESFSSVQDDLSKAEKQKSPN--KAELFSTARKTYSPAKHGKGRASEDAKQPCKS-AHRKEACSSPKASAKLALMKAKEESSYNETELLAARRKESATEPKGEKTTPKKTKVSPTKRESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLTFVITGVLESIERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKILDEDGLLDLIRTMPG---------KRSKYEMAAEAEMKKEKSKLERTPQKNDQGKRKISPAKKESESKKCKLTLLKNSPMKAVKKEASTCPRGLDVKETHGNRSS--------------NKEECLLWVDKYKPASLKNIIGQQGDQSCANKLLRWLRNWHKSSPEEKKHAAKFGKLASKDDGSSFKAALLSGPPGVGKTTTASLVCQELGYSYVELNASDTRSKNSLKAVVAESLNNTSIKGFYTSGAAPS--VSARHALIMDEVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIKSAMLSIAFKEGLKIPPPAMNEIILGANQDVRQVLHNLSMWCAQSKALTYDQAKADSQRAKKDIRLGPFDVTRKVFAAGEETAHMS----LMDKSDLFFHDYSIAPLFVQENYLHVKPVAAGGDMKKHLMLLSRAADSICDGDLVDNQIRS-KQNWSLLPTQAIYASVLPGELMRGYMTQFPSFPSWLGKHSSTGKHDRIVQDLSLHMSLRTYSSKRTVNMDYLSHIRDALVRPLTSQGVEGAQHVIKLMDTYYLMKEDFENIMEVSSWGGKP-SAFSKLDPKVKAAFTRAYNKEAHLTPYSLQVVKTSRLSTGPALDSEYSEEFQEDD-------TQS-EKEQDAVETDAMIKKKTRSSKPSKSEREKESKKGKGKNWKK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35251-1", "uniprot_id": "RFC1_HUMAN", "id": "P35251-1", "name": "Replication factor C subunit 1", "aln": "--MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPSKKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKKAASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKKMVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKKARKDTEAGE-TFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHSKSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSSPAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLESIERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIRTMPG---------KKSKYEIAVETEMKKE-SKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAKTIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIGQQGDQSCANKLLRWLRNWQKSSSEDKKHAAKFGKFSGKDDGSSFKAALLSGPPGVGKTTTASLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASS--VSTKHALIMDEVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIKGAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRAKKDIKMGPFDVARKVFAAGEETAHMS----LVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGDMKKHLMLLSRAADSICDGDLVDSQIRS-KQNWSLLPAQAIYASVLPGELMRGYMTQFPTFPSWLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQDVVALMDTYYLMKEDFENIMEISSWGGKP-SPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAIKASRHSTSPSLDSEYNEELNEDD-------SQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRKGKGKSSKK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35600-1", "uniprot_id": "RFC1_DROME", "id": "P35600-1", "name": "Replication factor C subunit 1", "aln": "MQRGIDSFFKRLP-------------AKAKSAEAE-----------------NGETPSKAPKRRKAVIISSDE--DEVVSPPETKKRKASKTAS------SEDDVVAATPEP------IAKKARNGQKP---------ALSKLKR---------------HVDPT---ELFG-----GETKRVIVPKPK-----------------------TKAVLE---FENEDIDRSLMEVDLDESIKEAAPEK----------------------------KVHSITRSSPSP--------------------------------------KRAKNSSPEPPKPKSTKSKATTPRVKKEKPAADLESSVLTDEE-----RHERKRASAVLYQKYKNRSSCLNPGSKEIPKGSPDCLSGLTFVVTGVLESMEREEAESVIKEYGGKVMTVVGKKLKYLVVGEEAGPKKLAVAEELNIPILSEDGLFDLIREKSGIAKQVKEEKKSPKKEHSSEEKGKKEVKTSRRSSDKKEKEATKLKYGEKH-DIAKHKVKEEHTSPKETKDKLNDVPAVTLKVKKEPSSQKEHPPSPR--TADLKTLDVVGMAWVDKHKPTSIKEIVGQAGAASNVTKLMNWLSKWYVN-HDGNKKPQRPNPWAKNDDGSFYKAALLSGPPGIGKTTTATLVVKELGFDAVEFNASDTRSKRLLKDEVSTLLSNKSLSGYFT-GQGQA--VSRKHVLIMDEVDGMAGNEDRGGMQELIALIKDSSIPIICMCNDRNHPKIRSLVNYCYDLRFQRPRLEQIKGKIMSICFKEKVKISPAKVEEIIAATNNDIRQSINHIALLSAKEDAS----QKSGQQVATKDLKLGPWEVVRKVFTA-DEHKHMS----FADKSDLFFHDYSLAPLFVQQNYLQVLPQ---GNKKDVLAKVAATADALSLGDLVEKRIRA-NSAWSLLPTQAFFSSVLPGEHMCGHFTGQINFPGWLGKNSKSGKRARLAQELHDHTRVCTSGSRLSVRLDYAPFLLDNIVRPLAKDGQEGVPAALDVMKDYHLLREDLDSLVELTSWPGKK-SPLDAVDGRVKAALTRSYNKEVMAYSYSAQAGIKKKKSEAAGADDDYLDEGPGEEDGAGGHLSSEEDEDKDNLELDSLIKAKKRTTTSKASGGSKKATSSTASKSKAKAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38630-1", "uniprot_id": "RFC1_YEAST", "id": "P38630-1", "name": "Replication factor C subunit 1", "aln": "-MVNISDFFGKNK----------------KSVRS------------------STSRPTRQVGSSKPEVIDLDTESDQESTNKTPKKMP-------------------------------------------------------------------------------------------------------------------------------------------VSNVIDVSETPEGEKK--------------------------------LPLPAKRKASSP---------------------------------------TVKPASSKKTKP-SSKSSDSASNITAQDVLDKIPSLDLSNVHVKENAKFDFKSANSNADPDEIVSEIG------SFPEGKPNCLLGLTIVFTGVLPTLERGASEALAKRYGARVTKSISSKTSVVVLGDEAGPKKLEKIKQLKIKAIDEEGFKQLIAGMPAE---------GGDGEAAEKARRKLEEQHNIATKEAELLVKKEEERSKKLAATRVSGGHLERDNVVREEDK----------------------------------------LWTVKYAPTNLQQVCGNKGS---VMKLKNWLANWENSKKNSFKHAGK-------DGSGVFRAAMLYGPPGIGKTTAAHLVAQELGYDILEQNASDVRSKTLLNAGVKNALDNMSVVGYFKHNEEAQNLNGKHFVIIMDEVDGMSGG-DRGGVGQLAQFCRKTSTPLILICNERNLPKMRPFDRVCLDIQFRRPDANSIKSRLMTIAIREKFKLDPNVIDRLIQTTRGDIRQVINLLSTISTTTKTINHENINEISKAWEKNIALKPFDIAHKMLDGQIYSDIGSRNFTLNDKIALYFDDFDFTPLMIQENYLSTRPSVLKPGQS-HLEAVAEAANCISLGDIVEKKIRSSEQLWSLLPLHAVLSSVYPASKVAGHMAGRINFTAWLGQNSKSAKYYRLLQEIHYHTRLGTSTDKIGLRLDYLPTFRKRLLDPFLKQGADAISSVIEVMDDYYLTKEDWDSIMEFFVGPDVTTAIIKKIPATVKSGFTRKYNSMTHPVAIYRTGSTIGGGGVGTSTSTPDFEDVVDADDNPVPADDEETQDSSTDLKKDKLIKQKAKPTKRKTATSKPGGSKKRKTKA------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* .** *. . . : * : . * :: .** .: :. . :: . *.: ** : * : : ::: .: . . : . :. . : * :. . . .:*:* :** ** :*.**** ::** :::: :.**.:* :..* . :*:* ::* .* * :.*:*: :** .. . * : : . * * . : : : : . :: : . . .: *. *: *:.:: : *: * . ** .** :* . : *:. : *... ::**:* ****:****:* ** :***:. :* ****.*** *: * *.* *: *::. . . :..:********:*. ****: :* : :.:. *:* :**:** **:*.: . * *::*:** :.**. :::*.::* .*: * ::.:* :. *:** :: :: .: .. : .: *:: : *:::.:*:: . * : ** *:*.*:.::**::*:**: . * . . * :: :*:.:. **:*:.:**: :. ***** :*. :** *.. : *::: .*..***::*.:.* * *:: * : * .: :.:** . : . :: *: .:* :. .: :*. *:* :** :.::*. . : :. : **:.:** **. . . . ... . :: .. :... :: * :** * :.:. . . . . .. ", "identical_positions": 185, "similar_positions": 301, "identity": "15.68%" }, { "cls_id": "homologset.agr.SGD:S000005745", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0C4DHM8-1", "uniprot_id": "A0A0C4DHM8_DROME", "id": "A0A0C4DHM8-1", "name": "Dipeptidyl peptidase 4", "aln": "-------------------MHTNMTSDRSGGGGGSWRLP---PDETLQVQ----------------------------------------------------DPKQKDHDFDFDEGHNWRSIILSLLVISFVVSGIVTAIYLLGYVDELLYWS--------GRRMILDEYLQGDLIPRRLPSSWVTTQK-YVFQSDDGSLAVLDTTTNLVKVLVTNHTLRQLN-----------------VRRYLCSSDLKYVLFTHN----------------------VKKNFQKSFTAFYTIYDVTN------------------------------------------DHHTPVKLKDTLKVQRTRLQYASWLGNTTAIIFVVKNDIFIRQSPLVEEDIRITSSG-------HENHIYNGVPDWLYQ--EEIFETPEAIWTSSDGTHFMYALFNDTNVGMMTYPWLSSGALFSG---------------------SGIFSGSIFPETKMVRFPTPGTTNPEVELWAVDITNLSDIQ---KFNIKPPATIYGQDYYLTSAGWISDSNCQVSVVYMGRSQNYSVISLCSK--EEDWKCLEVHSERAPEDEWLDIFPHPVFSS---------------------------------------DGSSFLFLANIQESENYQFTHIKHVMISQR----RISVISHGRYEVTK--ILCWDTINHKVYFMATQDKKPGQRHLY------SVQDPIHDDIRKVEPQCITCDLGDDLWSSRYYYTN-----------------CTHFEAFITPSLGVATN---------------------------YGIEFYILECQGPGLPVSGVHMQTTHSL----------------------------------VKILYDTRPFYTERLQKLALPTQRSFEVPLPHGGRAQVQLLLPPSWREELRDAAFPVIVEVNGRPGSESVSEKFKIDWGTYMSSRNDVVYIRLDVRGSKGQ---SKKTLYRHLGGVEVLDQISVIGYLLDT-IGFLDETRVGMWGWGYGGYVTSMALG-TQQDV-----FKCGIAVSPTADW--LYSTFTERILGLP--AENFKGYVEADATQRARLIKSNS-YFLIHGLADTTAPFVHGVQLAKSLTSANIL-FRYQTYADEGHDLSGV--LEHVYSSMEQYFAECLSLDPD----------------------------------------DTKPEVDNSIVPAE------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IR04-1", "uniprot_id": "Q8IR04_DROME", "id": "Q8IR04-1", "name": "Venom dipeptidyl peptidase 4", "aln": "---------------MVEIQKPHSALKRPSLKRETVVVNNSAPTIKKVTL----------------------------------------------------VPKDEELVAISPERRNWRGIFIALLVIAAVFSLIIFSIFLLSPEDEGLRIR--------GRRMLPSDILGRSLQWKPFNGTWSNGRE-LIYRDPTGGLSILNMADLTTRILMTNSTFRQLN-----------------AESFLVAPDQKYVLLQSDSNAEGSRHHVYEVQTANTFPLGPTENIAEAPRLQHVVWAPANPPPPLGAPPPSGASGASGASGASTTTMAPLPSGSIILNSLAGAANGPASAGASGSSAPNPNGKAGGYNLNQAIAFVHHNDIYYKPKVQGELVCRITQTGSGSLEGESTGVVFNGVPDWMYENVPELESRRSSMEFSPDGLFLAFLSYNDSEVNEYKYTWMG--------------------------------DDIKYPAVMSQRYPKTGSRNPNVTVNVVNLSVIKYIF---PTQIKLPSELS-NGSYVGGLTWASSTDLSVTVTNREQTKATTVLCRAP-----HFHCQAVHTEVTINDGWVLPSERPIFSVRNQGHNRLGKMVQNAEEIQAESQNVNVTDGQTHTTHEISNGGYLLKRLPVRDGEHGHYRHVVFISSLDR----RPVPLTMGRFEVTE--IVGWDEPHEIVYFMAAPEKRPGERHLYKISLKLNVTESNRTYITSTSPTCLTCDNTESTYRLHRARISQRGDRWEDIVARLEPDDCLYDIPKNCLFNRVQFS---------------------------QDYSYYVQECLGPEAPSVYLVETASNDK----------------------------------IYVLNAG-DVLRHRLSQLAIPQSRTFSVEIRHGFHAQVRLFLPPGMREEE-DVAFPLVLHVDASPGSQLVTERFHVDWNWYLASQRSFIVAQIDGRGSGFQGELLRTQVHGKLGTVEVEDQLGVLTYLRDN-LKFIDPLRICAFGWGYGGYASSMMLIDDSQQV-----LQCAVAINPIVNFGFHYSFFTERYIPLK--GDYLRALQEADLTMKAGNIKGRN-LMLMHGTADTLVHQEHTLMLVRALVEQQVK-FRHQVYPDEDHAIARS--LSHVYKTMEWYFDECFGPVDDNEWDPTGLFVFKQXLRPPYDPYDEDPLANQLSDIDIGPATDAHPDADAAGDSAGSNLSTLLTATTTSASLSALDELDNRLQALDLITSSTATTLSKVAGKLCNYSSKRRLHQSEAVLAQKSRILQH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "X2J9P4-1", "uniprot_id": "X2J9P4_DROME", "id": "X2J9P4-1", "name": "Venom dipeptidyl peptidase 4", "aln": "----------------------------------------------MPEQ----------------------------------------------------DNYDDELVSSNPNQRNWRGILIALLVIIIVLALIVTSVVLLTPPDEGPRVK--------GQRIKLQDIVDGLFVPQHSNGSWIDGEE-FLYQDHLGRICLLNAANRSERVLMSNVTFKTLS-----------------PFTFTISADKRYLLLAQN----------------------VVKLFRHSYLAQYTLYDIQT-------------------------------------------SESIKLRHSPHQDEWPYLHYARFTPAGNALVWVQSYDIYYREEVRSASVHRITHDA-------VPGVVYNGIPDWLYE--EEILHANNAIWMSDNGQLMLYATFNDTHVQEQHFAWYGTTGPSAGGAAAAAAVGAGGAGTGSPGAGGSNPHASLYPEIRSLRYPKPGTQNPTVTLRVADLKDPLKVH---ITDLHPPQIIANEDHYFSSASWVSHSKIAVVWLNRPQNISVVSVCKAP-----LFQCIETHRVSGDGRGWVDTVAVPLFAAN---------------------------------------ASIYVAISPLRDGLFGYFRHIVHVDIDKN----RVLPLTHGPYEVNR--LLHWDQLDNWIYFLGTPERLPSQQHLYR-----VSALPARQGQALRSPDCLTCPAVSQWSEGYDEGHTKSPPKLVTAWDDDWEDSEEAEAQPPQPALPVEQQPPGRGQSAPLPPPPSDCLYHEAKFPISRQAKYVLIDCLGPVVPTSILYGLKSAAADSAKTKRHSTQQEEPPTEGGDEKPGEEPKSQFLELLVIVQNNTRLKEKMAKTAMPQIKTFPVMISGGYHAQVRLYLPPVLREDE-ITRYPTILHVYSGPGSQLVTDHWHVDWNTYLSGSKDYIVVEIDGRGSAGQGYQLLHEVYKRLGSVEVSDQLEVSEYLRDN-LHFIDSRRMGVWGWSYGGYTAALALA-GQQSI-----FQCGISVSPVTNWKLYDSTYAERYLSFPNVTDNYKGYEESDLSKYVDNLRDRQ-FLLVHGTADDNVHVQQSMVLARSLTSKGVL-YKQQIYPDEGHSLSGV--KRHLYRSMTAFFEDCFKKLID----------------------------------------QQQQNQTDSMDFLDFHSFYGR-----------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6Q629-1", "uniprot_id": "DPP10_RAT", "id": "Q6Q629-1", "name": "Inactive dipeptidyl peptidase 10", "aln": "-------------------------------------------MNQTASVSHHIK----------------------CQPSK----------------------TIKELGSNSPPQRNWKGIAIALLVILVVCSLITMSVILLTP-DELTNSS--------ETRLSLEELLGKGFGLHNPEARWINDTD-VVYKTDNGHVMKLNAETNATTLLLDNSTFVTFK-----------------ASRHSLSPDLKYVLLAYD----------------------VKQIFHYSFTASYLIYNIHT---------------------------------------------GEVWELNPPEVEDSVLQYAAWGVQGQQLIYIFENNIYYQPDIKSSSLRLTSSGK--------EGIVFNGIADWLYE--EELLHSHIAHWWSPDGERLAFLMINDSLVPNMVIPRFTG---------------------------------ALYPKAKQYPYPKAGQANPSVKLYVVNLYGPTHTL---ELMP-PDIFKSR-EYYITMVKWVSNTRTVVRWLNRPQNISILTVCEST-------TGACSRKYEMTSDTWISKQNEEPVFSR--------------------------------------DGSKFFMTVPVKQGGRGEFHHIAMFLVQSKSEQITVRHLTSGNWEVIR--ILAYDETTQKIYFLSTEFS-PRGRQLYS-----------ASTEGLLSRDCISCNFRKEDCTYFDASFS-------------------------------------------------------------PMNQHFLLFCEGPKVPMVSLHSTDNPS-----------------------------------NYYILERNSMMKETIQKKKLAKREIRILHIDD-YELPLQLSFPKDFLEKN---QYALLLIIDEEPGGQMVTEKFHVDWDSVLIDTDNVIVARFDGRGSGFQGLKVLQEIHRRTGSVEAKDQIAAIKYLLK--QPYIDSKRLSIFGKGYGGYIASMILKSDEK------FFKCGTVVAPISDMKLYASAFSERYLGMP--SKEESTYQASSVLHNIHGLKEEN-LLIIHGTADTKVHFQHSAELIKHLIKAGVN-YTLQVYPDEGYHISDK-SKHHFYSTILRFFSDCLKEEVSVL--------------------------------------PQEPEEDE------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NXK7-1", "uniprot_id": "DPP10_MOUSE", "id": "Q6NXK7-1", "name": "Inactive dipeptidyl peptidase 10", "aln": "-------------------------------------------MKQEQQPTPGAR----------------------ATQSQP---------------------ADQELGSNSPPQRNWKGIAIALLVILVVCSLITMSVILLTP-DELTNSS--------ETRLSLEELLGKGFGLHNPEPRWINDTV-VVYKTNNGHVMKLNTESNASTLLLDNSTFVTFK-----------------ASRHSLSPDLKYVLLAYD----------------------VKQIFHYSFTASYLIYNIHT---------------------------------------------GEVWELNPPEVEDSVLQYAAWGVQGQQLIYIFENNIYYQPDIKSSSLRLTSSGK--------EGIIFNGIADWLYE--EELLHSHIAHWWSPDGERLAFLMINDSLVPNMIIPRFTG---------------------------------ALYPKAKQYPYPKAGQANPSVKLYVVNLYGPTHTL---ELMP-PDIFKSR-EYYITMVKWVSNTRTVVRWLNRPQNISILTLCEST-------TGACSRKYEMTSDTWLSKQNEEPVFSR--------------------------------------DGSKFFMTVPVKQGGRGEFHHIAMFLVQSKSEQITVRHLTSGNWEVIR--ILAYDETTQKIYFLSTESS-PQGRQLYS-----------ASTEGLLNRDCISCNFMKEDCTYFDASFS-------------------------------------------------------------PMNQHFLLFCEGPKVPVVSLHITDNPS-----------------------------------RYFLLENNSVMKETIQKKKLAKRETRILHIDD-YELPLQLSFPKDFMEKN---QYALLLIMDEEPGGQMVTDKFHVDWDSVLIDTDNVIVARFDGRGSGFQGLKVLQEIHRRIGSVEAKDQVAAVKYLLK--QPYIDSKRLSIFGKGYGGYIASMILKSDEK------FFKCGAVVAPISDMKLYASAFSERYLGMP--SKEESTYQASSVLHNIHGLKEEN-LLIIHGTADTKVHFQHSAELIKHLIKAGVN-YTLQVYPDEGYHISDK-SKHHFYSTILRFFSDCLKEEVSVL--------------------------------------PQEPEEDE------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N608-1", "uniprot_id": "DPP10_HUMAN", "id": "Q8N608-1", "name": "Inactive dipeptidyl peptidase 10", "aln": "-------------------------------------------MNQTASVSHHIK----------------------CQPSK----------------------TIKELGSNSPPQRNWKGIAIALLVILVVCSLITMSVILLTP-DELTNSS--------ETRLSLEDLFRKDFVLHDPEARWINDTD-VVYKSENGHVIKLNIETNATTLLLENTTFVTFK-----------------ASRHSVSPDLKYVLLAYD----------------------VKQIFHYSYTASYVIYNIHT---------------------------------------------REVWELNPPEVEDSVLQYAAWGVQGQQLIYIFENNIYYQPDIKSSSLRLTSSGK--------EEIIFNGIADWLYE--EELLHSHIAHWWSPDGERLAFLMINDSLVPTMVIPRFTG---------------------------------ALYPKGKQYPYPKAGQVNPTIKLYVVNLYGPTHTL---ELMP-PDSFKSR-EYYITMVKWVSNTKTVVRWLNRAQNISILTVCETT-------TGACSKKYEMTSDTWLSQQNEEPVFSR--------------------------------------DGSKFFMTVPVKQGGRGEFHHVAMFLIQSKSEQITVRHLTSGNWEVIK--ILAYDETTQKIYFLSTESS-PRGRQLYS-----------ASTEGLLNRQCISCNFMKEQCTYFDASFS-------------------------------------------------------------PMNQHFLLFCEGPRVPVVSLHSTDNPA-----------------------------------KYFILESNSMLKEAILKKKIGKPEIKILHIDD-YELPLQLSLPKDFMDRN---QYALLLIMDEEPGGQLVTDKFHIDWDSVLIDMDNVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLK--LPYIDSKRLSIFGKGYGGYIASMILKSDEK------LFKCGSVVAPITDLKLYASAFSERYLGMP--SKEESTYQAASVLHNVHGLKEEN-ILIIHGTADTKVHFQHSAELIKHLIKAGVN-YTMQVYPDEGHNVSEK-SKYHLYSTILKFFSDCLKEEISVL--------------------------------------PQEPEEDE------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z218-1", "uniprot_id": "DPP6_MOUSE", "id": "Q9Z218-1", "name": "A-type potassium channel modulatory protein DPP6", "aln": "-----------------------------------------------------------------MNQTAGASNNVRCPPGKG----------------------HKELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAEDTSLSQ--------KKKVTVEDLFSEDFKIHDPEAKWISNKE-FIYRERKGSVILRNVETNNSTVLIEGKKIESLR-----------------AIRYEISPDKEYVLFSYN----------------------VEPVYQHSHTGYYVLSKIPH---------------------------------------------GDPQSLDPPEVSNAKLQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGK--------EGVIYNGLSDWLYE--EEILKSHIAHWWSPDGTRLAYATINDSRVPLMELPTYTG---------------------------------SVYPTVKPYHYPKAGSENPSISLHVIGLNGPTHDL---EMMP-PDDPRMR-EYYITMVKWATSTKVAVTWLNRAQNVSILTLCDAT-------TGVCTKKHEDESEAWLHRQNEEPVFSK--------------------------------------DGRKFFFVRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITSGDWDVTK--ILSYDEKRNKIYFLSTEDL-PRRRHLYS-----------ANTVDDFNRQCLSCDLVE-NCTYVSASFS-------------------------------------------------------------HNMDFFLLKCEGPGVPTVTVHNTTDKR-----------------------------------RMFDLEANEEVQKAINDRQMPKIEYRKIEVED-YSLPMQILKPATFTDTA---HYPLLLVVDGTPGSQSVTERFEVTWETVLVSSHGAVVVKCDGRGSGFQGTKLLQEVRRRLGFLEEKDQMEAVRTMLK--EQYIDKTRVAVFGKDYGGYLSTYILPAKGENQ--GQTFTCGSALSPITDFKLYASAFSERYLGLH--GLDNRAYEMTKLAHRVSALEDQQ-FLIIHATADEKIHFQHTAELITQLIKGKAN-YSLQIYPDESHYFHSVALKQHLSRSIIGFFVECFRVQDKLP--------------------------------------TATAKEEEEED---------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46101-1", "uniprot_id": "DPP6_RAT", "id": "P46101-1", "name": "A-type potassium channel modulatory protein DPP6", "aln": "--------------------------MASLYQRFTGKINTSRSFPAPPEASHLLGGQGPEED--AGSKPLGPQAQAVAPRERGG----AGGRPRFQYQARSDCDEEDELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAEDTSLSQ--------KKKVTVEDLFSEDFKIHDPEAKWISDKE-FIYRERKGSVILRNVETNNSTVLIEGKKIESLR-----------------AIRYEISPDKEYALFSYN----------------------VEPVYQHSHTGYYVLSKIPH---------------------------------------------GDPQSLDPPEVSNAKLQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGK--------EGVIYNGLSDWLYE--EEILKSHIAHWWSPDGTRLAYATINDSRVPLMELPTYTG---------------------------------SVYPTVKPYHYPKAGSENPSISLHVIGLNGPTHDL---EMMP-PDDPRMR-EYYITMVKWATSTKVAVTWLNRAQNVSILTLCDAT-------TGVCTKKHEDESEAWLHRQNEEPVFSK--------------------------------------DGRKFFFVRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITSGDWDVTE--ILTYDEKRNKLYFLSTEDL-PRRRHLYS-----------ANTVDDFNRQCLSCDLVE-NCTYVSASFS-------------------------------------------------------------HNMDFFLLKCEGPGVPTVTVHNTTDKR-----------------------------------RMFDLEANEQVQKAIYDRQMPKIEYRKIEVED-YSLPMQILKPATFTDTA---HYPLLLVVDGTPGSQSVSERFEVTWETVLVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGFLEEKDQMEAVRTMLK--EQYIDKTRVAVFGKDYGGYLSTYILPAKGENQ--GQTFTCGSALSPITDFKLYASAFSERYLGLH--GLDNRAYEMTKLAHRVSALEDQQ-FLIIHATADEKIHFQHTAELITQLIKGKAN-YSLQIYPDESHYFHSVALKQHLYRSIIGFFVECFRIQDKLP--------------------------------------TATAKEDEEED---------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42658-1", "uniprot_id": "DPP6_HUMAN", "id": "P42658-1", "name": "A-type potassium channel modulatory protein DPP6", "aln": "--------------------------MASLYQRFTGKINTSRSFPAPPEASHLLGGQGPEEDGGAGAKPLGPRAQAAAPRERGGGGGGAGGRPRFQYQARSDGDEEDELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAEDNSLSQ--------KKKVTVEDLFSEDFKIHDPEAKWISDTE-FIYREQKGTVRLWNVETNTSTVLIEGKKIESLR-----------------AIRYEISPDREYALFSYN----------------------VEPIYQHSYTGYYVLSKIPH---------------------------------------------GDPQSLDPPEVSNAKLQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGK--------EGVIYNGLSDWLYE--EEILKTHIAHWWSPDGTRLAYAAINDSRVPIMELPTYTG---------------------------------SIYPTVKPYHYPKAGSENPSISLHVIGLNGPTHDL---EMMP-PDDPRMR-EYYITMVKWATSTKVAVTWLNRAQNVSILTLCDAT-------TGVCTKKHEDESEAWLHRQNEEPVFSK--------------------------------------DGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITSGDWDVTK--ILAYDEKGNKIYFLSTEDL-PRRRQLYS-----------ANTVGNFNRQCLSCDLVE-NCTYFSASFS-------------------------------------------------------------HSMDFFLLKCEGPGVPMVTVHNTTDKK-----------------------------------KMFDLETNEHVKKAINDRQMPKVEYRDIEIDD-YNLPMQILKPATFTDTT---HYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLK--EQYIDRTRVAVFGKDYGGYLSTYILPAKGENQ--GQTFTCGSALSPITDFKLYASAFSERYLGLH--GLDNRAYEMTKVAHRVSALEEQQ-FLIIHPTADEKIHFQHTAELITQLIRGKAN-YSLQIYPDESHYFTSSSLKQHLYRSIINFFVECFRIQDKLL--------------------------------------TVTAKEDEEED---------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NHZ0-1", "uniprot_id": "A0A8M1NHZ0_DANRE", "id": "A0A8M1NHZ0-1", "name": "", "aln": "--------------------------MASLYQRFSGKINTNKSFPHPPEASHLLGGQVPEEENKSGKSPHHPSCRPPLPRHRGGGGAGSGGRGSLQKQARMDADNEGELVGGSAPQRNWKGIAIALLVILVICSLIVTSVILLTPVEDTSLAS--------KQKVTIEDIFSGKLQAHNPQATWLSDTE-LLYHDHDGNVKMLNIQTNYNKTLVENKTFETYR-----------------PTQYQVSPDLKYVLLAYN----------------------IMPIYQYSFMAYYIICSLDS---------------------------------------------PERVELTPNEVQSTALQYAGWGPKGQQLIFIFENNIYYKAQVNSPSIRLVSTGS--------LGVIFNGLADWLYE--EEIFQNHIAHWWSPDGLRLAYATINDTLVPKMEIPMFTS---------------------------------VLYPNGQEYRYPKAGEENPEIYLSVVSLNGPLHTV---RMKK-PEDPRIRKDYYITMVKWATSTKLAVNWLNRAQNSSILTLCEAT-------TGICTKKHEDESDSWLHRQNEPPLFSK--------------------------------------DGYRFFFTRAVPQGGRGKFFHISMSTSQPNSSTDTLQSLTSGDWDVTQ--ILAYNEDTRIVYFLSTEDG-ASRRQLYS-----------ANTTGSFNRRCLSCNFR---CGYVSGSFS-------------------------------------------------------------PDANYFFLNCKGPGVPHSAVYSTRYGQY---------------------------------EKILDVETNELLNVTVNNTQMPIVEYRNVNIDD-YVLSMQILKPAVFVATS---HYPLLLLVDGTPGGQMVTEQFQVDWSTVLVSSFNTIVVRLDGRGSGFQGTNLLHRVKKKLGEFEERDHLEALRIMSQ--MTYIDNSRIGVYGKAYGGYLASRLLHLDESPNLSKIKIKCGTAVSPITDFSIYASAFSERYLGLP--QINKREYEMARLTDRMEQLRDKK-LMIIHPTADEKVHFQHTAKFINHLINEKAN-YTLQIYPDEGHFLNSKDSQQHLSQSLVNFFVECFTPPEIIQ--------------------------------------SEEKQD-NEDDG--------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AP34-1", "uniprot_id": "A0A8M3AP34_DANRE", "id": "A0A8M3AP34-1", "name": "A-type potassium channel modulatory protein DPP6", "aln": "-----------------------------------------MIFDHVSSARLVS-----------------------LPRKRS--------------KVESAKKFWKELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPGEDDSLAF--------KEKVTVEEIFKKDFKVHDPNAKWISNNE-LLYRTREGDVVRFNMETNESTILVTNRKFEMYK-----------------ASKYEVSPDMKLVLLAYN----------------------VQLVYEHSFTADYIICSLET---------------------------------------------PETWILNPPEVRNAHLQYAGWGPRGQQLIFIFENNIYYRATVENRSIRLVSTGK--------EGVIFNGLTDWLYE--AEIFKSHIAHWWSPDGARLAYATINDTLVPRMEIPMFTG---------------------------------SLYPTARQYHYPKAGEENPIISLYVVNLNGPLHTI---EMRR-PEDQRIG-EYYVTMVKWATSTKLAVNWLNRAQNISILTLCVAT-------TGVCTKKHEDESEGWLHRQNEEPLFSK--------------------------------------DGLRLFFTRAIPQGGRGKFFHISMSISQPNSSTDTLQSITSGDWDVTQ--VLAYDEESQLIYFLSTEDD-PKRRHLYS-----------ADTVGTFNRRCLSCDFTD-SCGYVSGSFS-------------------------------------------------------------PTMDYFLLNCKGPGVPYAAVYSTHDRQ-----------------------------------KVQDIELNLNLRRKVNSMQMPRVEYREINIED-YSLSVQILKPAGFIDTS---HYPLLLLVDGTPGSQSVSEQFHIDWASVLVSSFGVVAVRFDGRGSGFQGTNLLHKVQRRLGMFEEKDQLDVLSIMMQ--EPYIDKTRIGAFGQVYGGYITSLLLSSEDS------MLKCAAVLSPITDFALYASAFSERYLGPP--KPDRRAYEMANLAYRASQFIDKK-FLIIHPTADEKVHFQHTAKFISRLISERAN-YSLQIYPDEGHFIHNELTRQHLSQSLVNFFEECFRLPDLVF--------------------------------------EEALEEESEEEG--------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P97321-1", "uniprot_id": "SEPR_MOUSE", "id": "P97321-1", "name": "Prolyl endopeptidase FAP", "aln": "-------------------------------------------------------------------------------------------------------------------MKTWLKTVFGVTTLAALALVVICIVLRPSRVYKPEGNT--------KRALTLKDILNGTFSYKTYFPNWISEQE-YLHQSEDDNIVFYNIETRESYIILSNSTMKSVN-----------------ATDYGLSPDRQFVYLESD----------------------YSKLWRYSYTATYYIYDLQN------------------------------------------------GEFVRGYELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITYTGR--------ENRIFNGIPDWVYE--EEMLATKYALWWSPDGKFLAYVEFNDSDIPIIAYSYYGDG---------------------------------QYPRTINIPYPKAGAKNPVVRVFIVDTTYPHHVG---PMEVPVPEMIASSDYYFSWLTWVSSERVCLQWLKRVQNVSVLSICDFREDWHAWECPKNQEHVEESRTGWAGGFFVSTPAFSQ-------------------------------------DATSYYKIFSDKDG----YKHIHYIKDTVEN----AIQITSGKWEAIY--IFRVTQDS-LFYSSNEFEGYPGRRNIYR----------ISIGNSPPSKKCVTCHLRKERCQYYTASFS-------------------------------------------------------------YKAKYYALVCYGPGLPISTLHDGRTDQE-----------------------------------IQVLEENKELENSLRNIQLPKVEIKKLKDGG-LTFWYKMILPPQFDRSK---KYPLLIQVYGGPCSQSVKSVFAVNWITYLASKEGIVIALVDGRGTAFQGDKFLHAVYRKLGVYEVEDQLTAVRKFIE--MGFIDEERIAIWGWSYGGYVSSLALASGTG------LFKCGIAVAPVSSWEYYASIYSERFMGLPTKDDNLEHYKNSTVMARAEYFRNVD-YLLIHGTADDNVHFQNSAQIAKALVNAQVD-FQAMWYSDQNHGISSGRSQNHLYTHMTHFLKQCFSLSD-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AEN0-1", "uniprot_id": "A0A8I6AEN0_RAT", "id": "A0A8I6AEN0-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------MKTWLKTVFGVTTLVALALVVICIVLRPSRVYSPEGNT--------GRSLTLKDILNGTFSYKTYFPNWISEQE-YLHQSEDDNIVFYNIETRESYIILSNSTMKSVN-----------------ATDYGLSPDRQFIYLESD----------------------YSKLWRYSYTATYYIYDLQN------------------------------------------------GEFVRGYELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITYTGR--------ENRIFNGIPDWVYE--EEMLATKYALWWSPDGKYLAYVEFNDSDIPIIAYSYYGDG---------------------------------QYPRTINIPYPKAGAKNPIVRVFIVDTIYPHHVG---PIEVPVPEMIASSDYYFTWLTWVTNERVCLQWLKRVQNVSVLSICDFREDWHAWDCPKNQEHIEESRTGWAGGFFVSTPAFSQ-------------------------------------DAASYYKIFSDKDG----YKHIHYIKDTVEN----AIQITSGKWEAIY--IFRVTQDS-LFYSSNEFEGYPGRRNIYR----------ISIGNSPPSKKCVTCHLRKERCQYYTASFS-------------------------------------------------------------YKAKYYALICYGPGLPISTLHDGRTDQE-----------------------------------IQVLEENKELENALRNIQLPAVEIKKLEDGG-MTFWYKMILPPQFDRSK---KYPLLIQVYGGPCSQSVKSVFSVNWITYLASKEGIVVALVDGRGTAFQGDKFLHAVYRKLGVYEVEDQLTAVRKFIE--MGFIDEGRIAIWGWSYGGYVSSLALASGTG------LFKCGIAVAPVSSWEYYASIYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVD-YLLIHGTADDNVHFQNSAQIAKALVNAQVD-FQAMWYSDQNHGISSGRSQNHLYTHMTHFLKQCFSLSD-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12884-1", "uniprot_id": "SEPR_HUMAN", "id": "Q12884-1", "name": "Prolyl endopeptidase FAP", "aln": "-------------------------------------------------------------------------------------------------------------------MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENT--------MRALTLKDILNGTFSYKTFFPNWISGQE-YLHQSADNNIVLYNIETGQSYTILSNRTMKSVN-----------------ASNYGLSPDRQFVYLESD----------------------YSKLWRYSYTATYYIYDLSN------------------------------------------------GEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGR--------ENKIFNGIPDWVYE--EEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDE---------------------------------QYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVG---PQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSY-------------------------------------DAISYYKIFSDKDG----YKHIHYIKDTVEN----AIQITSGKWEAIN--IFRVTQDS-LFYSSNEFEEYPGRRNIYR----------ISIGSYPPSKKCVTCHLRKERCQYYTASFS-------------------------------------------------------------DYAKYYALVCYGPGIPISTLHDGRTDQE-----------------------------------IKILEENKELENALKNIQLPKEEIKKLEVDE-ITLWYKMILPPQFDRSK---KYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIE--MGFIDEKRIAIWGWSYGGYVSSLALASGTG------LFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVD-YLLIHGTADDNVHFQNSAQIAKALVNAQVD-FQAMWYSDQNHGLS-GLSTNHLYTHMTHFLKQCFSLSD-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P14740-1", "uniprot_id": "DPP4_RAT", "id": "P14740-1", "name": "Dipeptidyl peptidase 4", "aln": "-------------------------------------------------------------------------------------------------------------------MKTPWKVLLGLLGVAALVTIITVPVVLLNKDE-AAADS--------RRTYTLADYLKNTFRVKSYSLRWVSDSE-YLYK-QENNILLFNAEHGNSSIFLENSTFEIFGDS---------------ISDYSVSPDRLFVLLEYN----------------------YVKQWRHSYTASYSIYDLNK------------------------------------------------RQLITEEKIPNNTQWITWSQEGHKLAYVWKNDIYVKIEPHLPSHRITSTGK--------ENVIFNGINDWVYE--EEIFGAYSALWWSPNGTFLAYAQFNDTGVPLIEYSFYSDES-------------------------------LQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSSTTTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTLVWNCPTTQEHIETSATGWCGRFRPAEPHFTS-------------------------------------DGSSFYKIVSDKDG----YKHICQFQKDRKPEQ-VCTFITKGAWEVIS--IEALTSDY-LYYISNEYKEMPGGRNLYK----------IQLTDHT-NKKCLSCDLNPERCQYYSVSLS-------------------------------------------------------------KEAKYYQLGCRGPGLPLYTLHRSTDQKE-----------------------------------LRVLEDNSALDKMLQDVQMPSKKLDFIVLNE-TRFWYQMILPPHFDKSK---KYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLK--MGFVDSKRVAIWGWSYGGYVTSMVLGSGSG------VFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVE-YLLIHGTADDNVHFQQSAQISKALVDAGVD-FQAMWYTDEDHGIASSTAHQHIYSHMSHFLQQCFSLR--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VMM2-1", "uniprot_id": "Q9VMM2_DROME", "id": "Q9VMM2-1", "name": "Venom dipeptidyl peptidase 4", "aln": "--------------------------------------------------------------------------------------------------------------------MPINPLLITAFGLFITVCPRPSTAAAVIGRVDGAEGN--------KTAWELTEALYGTSGLRSFNGTWITG---TYYTATDRSIHKFNAATKTDVIFQNSSFLNNYVG-----------------ATFSLSPDNTKILIRHN----------------------LTEKFRHSYIAQYDVFDIET-------------------------------------------------NTTVQIHKGEKLQYCGWSPLRDRLAYVYLNNVFIHFS--ESLEISITDDG-------VDGVVYNGVPDWVYE--EEVLSSGSAIWWSSDGSRLAVGFFNDTEVETFTYFLYGDG----------------------------ATTFYQYPHEEQLKYPKSGSKNPVVSLRVYDVSDNDPTMH----TIVAPVDIVGDDHILQSVVWSNSTHLLITWMNRRQNLTSIQSCSYEG-------DCVEVKRLEEPQGWVDISTPKCLSTG-------------------------------------------------KSCIFGYFIDNWHQVWNLDLETGLNSWQSRGNFTVLS--VYGYDEARDKLYYQATLPGDPSVYHVFS---------------NDECLSCGQIDADGAACRSASGTFS-------------------------------------------------------------KSFSYYTLSCTGPNPSYTRIFEASTKTL-----------------------------------QVDWEPNTAYRKQIEEKLRPSYRFMNVTLADGSIGYAKLALPPNFVETK---KYPLIVVVYQGPNSVRVTNGFTLGYEAFVTTSRDTIYAYIDGRGTGNKGKDLLFSVNNDLGDHEVEDQLFVTRWMQQN-LAFVDAERCGIWGWSYGGYMTAKTIEKDDDR-----VFQCGVSVAPVTSWLYYDTIYTERYMGLPTDDDNLKKYNESSVFGNLENFKSHD-FLLIHGSGDDNVHYQHSLLLAKLLQRQDIQ-FEEQTYTDENHGIGNA--LPHLYHTIDAFWTNCLNLDVYEDSA--------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33894-1", "uniprot_id": "STE13_YEAST", "id": "P33894-1", "name": "Dipeptidyl aminopeptidase A", "aln": "MSASTHSHKRKNSHLFPQRKSSNSSMDKPFFPNNDSVANTDPQSNENGHTINEIRPTEATIDVTDVPQTPFLQEQYSMRPRRESFQFNDIENQHHTHSFFSVNKFNRRWGEWSLPEKRSYVLVFTLIALSVLVLLVILIPSKLLPTKITRPKTSAGDSSLGKRSFSIENVLNGDFAIPEDTFHFIDPPQRLLGQDSDPGLYFTTKEIDGHTNFIAKQLFDETFEVNLGGNRFLYEGVEFTVSTVQINYKLDKLIFGTN----------------------LESEFRHSSKGFYWIKDLNTG--------------------------------------NIEPILPPEKSDDNYELGLSKLSYAHFSPAYNYIYFVYENNLFLQQVNSGVAKKVTEDGS---------KDIFNAKPDWIYE--EEVLASDQAIWWAPDDSKAVFARFNDTSVDDIRLNRYTNMN-------------------------------EAYLSDTKIKYPKPGFQNPQFDLFLVNLQNGIIYS---------INTGGQKDSILYNGKWISPDTFRFEITDRNSKILDVKVYDIPS----SQMLTVRNTNSNLFNGWIEKTKDILSIPPK---------------------------------------PELKRMDYGYIDIHADSRGFSHLFYYPTVFAKEPIQLTKGNWEVTGNGIVGYEYETDTIFFTANEIG-VMSQHLYS----------ISLTDSTTQNTFQSLQNPSDKYDFYDFELS-------------------------------------------------------------SSARYAISKKLGPDTPIKVAGPLTRVLN---------------------------VAEIHDDSILQLTKDEKFKEKIKNYDLPITSYKTMVLDDGVEINYIEIKPANLNPKK---KYPILVNIYGGPGSQTFTTKSSLAFEQAVVSGLDVIVLQIEPRGTGGKGWSFRSWAREKLGYWEPRDITEVTKKFIQRNSQHIDESKIAIWGWSYGGFTSLKTVELDNGDT-----FKYAMAVAPVTNWTLYDSVYTERYMNQP--SENHEGYFEVSTIQNFKSFESLKRLFIVHGTFDDNVHIQNTFRLVDQLNLLGLTNYDMHIFPDSDHSIRYHNAQRIVFQKLYYWLRDAFAERFDNTEVLHL-----------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : : : : . : : : : : : :: ::: ::*. **:*: *: : : :. **: : : :*..* ** . . . . * . . . * : * : . : : ::: . . ** . : . : * :. :: : * . : : : . : : **: : * * * . : . .:* : :* ***: : : : . : * : ::** : : . :::* * : : * : :.*..: . . : : :.: ", "identical_positions": 35, "similar_positions": 107, "identity": "2.67%" }, { "cls_id": "homologset.agr.SGD:S000005747", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZPF2-1", "uniprot_id": "D3ZPF2_RAT", "id": "D3ZPF2-1", "name": "Malonyl-CoA-acyl carrier protein transacylase, mitochondrial", "aln": "--MNARVARACWAWGSWG--RRPASSLREPPPDAVDVAGLLRDSSVTEEGVQEAVARR----PPSRCSVLLFPGQGSQAVGMGGGLLHFPRVRQLYEAAHRVLGYDLLELCLRGPQEDLDRTVHCQPAVFVASLAAVEKLHHLQPAVIENCVAAAGFS----VGEFAALVFAGAMEFAEGLYAVKVRAEAMQEASEAVPSGMLS--VLGQRQSNFSFACLEAQEHCRSLGIENPVCQVSNYLFPDCRVISGHLEALQFLRKNSAKFHFRRTKMLPVSGGFHTCLMEPAVEPLMKTLGSINIKKPLVAVHSNVSGHKYTHPQHIRKLLGQQVVSPVKWEQTMHCIYERKKGMEVLQP-------------RGCDADPFGP----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R3F5-1", "uniprot_id": "FABD_MOUSE", "id": "Q8R3F5-1", "name": "Malonyl-CoA-acyl carrier protein transacylase, mitochondrial", "aln": "--MSARVARAGWAWRSWG--RRAASSLREPPPDAVDVAELLRDSSVAEEGAQEAVARRR---PPSQCSVLLFPGQGCQAVGMGSGLLHLPRVRQLYEAAHRVLGYDLLELCLRGPQEDLDRTVHCQPAVFVASLAAVEKLHHLQPAVIDNCVAAAGFS----VGEFAALVFAGAMDFSEGLYAVKARAEAMQEASEAVPSGMLS--VLGQRQSNFSFACLEAQEHCKSLGIENPVCQVSNYLFPDCRVISGHLEALQFLRRNSAKYHFRRTKMLPVSGGFHTCLMEPAVDPLMKVLGSINIKKPLVAVHSNVSGQKYTHPQHIRKLLGQQVVSPVKWEQTMHSIYERKKGMEFPSTYEVGPGQQLGSILKCCNRQAWKSYSHVDVMQNIMDPDP-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IVS2-1", "uniprot_id": "FABD_HUMAN", "id": "Q8IVS2-1", "name": "Malonyl-CoA-acyl carrier protein transacylase, mitochondrial", "aln": "--MSVRVARVAWVRGLGASYRRGASSFPVPPPGAQGVAELLRDATGAEEEAPWAATERR---MPGQCSVLLFPGQGSQVVGMGRGLLNYPRVRELYAAARRVLGYDLLELSLHGPQETLDRTVHCQPAIFVASLAAVEKLHHLQPSVIENCVAAAGFS----VGEFAALVFAGAMEFAEGLYAVKIRAEAMQEASEAVPSGMLS--VLGQPQSKFNFACLEAREHCKSLGIENPVCEVSNYLFPDCRVISGHQEALRFLQKNSSKFHFRRTRMLPVSGAFHTRLMEPAVEPLTQALKAVDIKKPLVSVYSNVHAHRYRHPGHIHKLLAQQLVSPVKWEQTMHAIYERKKGRGFPQTFEVGPGRQLGAILKSCNMQAWKSYSAVDVLQTLEHVDLDPQEPPR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8T3L6-1", "uniprot_id": "FABD_DROME", "id": "Q8T3L6-1", "name": "Probable malonyl-CoA-acyl carrier protein transacylase, mitochondrial", "aln": "MLAARRLLRSPRITGALSWSRWSSDAAKATTETSALLQNAEKRQQLLNELSEPLEQKGRPAIDPKETSVMLFPGQGTQYVGMAKDLLRFPGARRIFELANEVLKYDLLKICLEGPREKLNRTEHAQLAVMVSSLAALEQLREERPKAIETCVAAAGFS----LGEITALVYADALPFDKALRLVQVRATAMQAACDQAAGAMAM--TLYGPDTNLGEACARAQQWCLDKGVESPYCGIANYMYPHCKVVAGNVEALEFLEQNAKSFKIRRMKRLAVSGAFHTPLMQSAVEPFTKALKTVRLQDPVIRVYSNVDGKPYRHAKHILTQLPKQIVRPVKWEQTLHEMYERKQGVDFPRTFECGPGKGLVQVLEKVNAKAAQSSFNVIA----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12283-1", "uniprot_id": "FABD_YEAST", "id": "Q12283-1", "name": "Malonyl CoA-acyl carrier protein transacylase, mitochondrial", "aln": "----MKLLTFP---------------GQGTSISISILKAIIRNK--SREFQTILSQNGK---ESNDLLQYIFQNPSSPGSIAVCSNLFYQLYQILSNPSDPQDQAPKNMTKIDSP----DKKDNEQCYLLGHSLGELTCLSVNSLFSLKDLFDIANFRNKLMVTSTEKYLVAHNINRSNKFEMWALSSPRATDLPQEVQKLLNSPNLLSSSQNTISVANANSVKQCVVTGLVDDLESLR----TELNLRFPRLRITELTNPYNIPFHN-STVLRPVQEPLYDYIWD-----ILKKNGTHTLMELNHPIIANLDGNISYYIHHALDRFVKCSSRTVQFTMCYDTINSG-TPVEIDKSICFGPGNVIYNLIRRNCPQVDTIEYTSLATIDAYHKAAEENKD--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .. : : .* . . :* . . . * : : : : .* ::. : * :: **. : * :. . *.* : . : * : : : : : . : * :..:. * .: : * *: . : .. .: . . .: . :: .*. :: : : : : : : . : :*: .: : * : : .*:: . : . . . . . ", "identical_positions": 19, "similar_positions": 91, "identity": "4.74%" }, { "cls_id": "homologset.agr.SGD:S000005748", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99JD3-1", "uniprot_id": "ODC_RAT", "id": "Q99JD3-1", "name": "Mitochondrial 2-oxodicarboxylate carrier", "aln": "MSAS--NVSLLHETCRQVAAGGCAGLVEICLMHPLDVVKTRFQVQRSVTD-------PQSYKSLRDSFQVIFRTEGLFGFYKGIIPPILAETPKRAVKFSTFELYKKFLG--YMSLSPG-LTFPIAGLGSGLTEAVVVNPFEVVKVGLQVNRNMFTEQPSTFAYARQIIKKEGWGFQGLNKGFTATLGRHGIFNMTYFGFYYNVKDNIPSSKDPTLEFLRKFGIGFVSGTVGSVFNIPFDVAKSRIQGPQPVPGEIK-YRGCFKTMETVYREEGILALYKGLLPKVMRLGPGGGVMLLVYEYTYAWLQENW---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZ09-1", "uniprot_id": "ODC_MOUSE", "id": "Q8BZ09-1", "name": "Mitochondrial 2-oxodicarboxylate carrier", "aln": "MSAS--NVSLLHETSRQVAAGGSAGLVEICLMHPLDVVKTRFQVQRSVTD-------PQSYRTVRGSFQMIFRTEGLFGFYKGIIPPILAETPKRAVKFSTFELYKKFLG--YMSLSPG-LTFLIAGLGSGLTEAVVVNPFEVVKVGLQVNRNLFKEQPSTFAYARQIIKKEGLGFQGLNKGLTATLGRHGIFNMVYFGFYHNVKNIIPSSKDPTLEFLRKFGIGFVSGTMGSVFNIPFDVAKSRIQGPQPVPGEIK-YRSCFKTMEMIYREEGILALYKGLVPKVMRLGPGGGVMLLVYEYTYAWLQENW---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQT8-1", "uniprot_id": "ODC_HUMAN", "id": "Q9BQT8-1", "name": "Mitochondrial 2-oxodicarboxylate carrier", "aln": "MSAKP-EVSLVREASRQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATD-------PNSYKSLVDSFRMIFQMEGLFGFYKGILPPILAETPKRAVKFFTFEQYKKLLG--YVSLSPA-LTFAIAGLGSGLTEAIVVNPFEVVKVGLQANRNTFAEQPSTVGYARQIIKKEGWGLQGLNKGLTATLGRHGVFNMVYFGFYYNVKNMIPVNKDPILEFWRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIK-YRTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAVMLLVYEYTYSWLQENW---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3T2-1", "uniprot_id": "Q9V3T2_DROME", "id": "Q9V3T2-1", "name": "Mitochondrial 2-oxodicarboxylate carrier", "aln": "MAGQQHDISHAKRAAFQVLAGGSAGFLEVCIMQPLDVVKTRIQIQATPAPNAAA-LGEVHYNGVFDCFAKMYRHEGISSYWKGIMPPILAETPKRAIKFLVFEQTKPLFQ--FGSPTPTPLTFSLAGLTAGTLEAIAVNPFEVVKVAQQADR--QKKMLSTFAVAKGIIQQDGLGFSGLNKGITATMGRNGVFNMVYFGFYHSVKNVVPEYKESHLEFLRKVTIGFLAGTLACFVNIPFDVAKSRIQGPQPVPGQIK-YRGTLSSMGIVYREEGFRALYKGLVPKIMRLGPGGAILLLVFEYSYDYLLHNYS--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLF1-1", "uniprot_id": "Q9VLF1_DROME", "id": "Q9VLF1-1", "name": "Mitochondrial 2-oxodicarboxylate carrier", "aln": "MATRS-EETVRSLAHWQFLAGGLSGFIEIICFHPLDVVKTRMQIQGAHPFG-----GEVVYTCPLDAIVKIYRYEGLSSLWKGIVPPICVETPKRGGKFLMYESLKPYFQ--FGAPQPTPLTHAMSGSMAAILESFLVNPFEVVKITQQAHR---GKRLKTLSVVKYIIKHDGYGIKGLYRGITALVARNAVFHFGFFGFYNALKDIVPSPEDKTYNILRKVIIAGLASSLACVMSVTLDMAKCRIQGPQPVKGEVK-YQWTISTIKSTFKEEGFRSLFKGLGAMILRVGPGGAMLLVTYEYLFEFLKSQNI--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99297-1", "uniprot_id": "ODC2_YEAST", "id": "Q99297-1", "name": "Mitochondrial 2-oxodicarboxylate carrier 2", "aln": "MSSDS--NAKPLPFIYQFISGAVAGISELTVMYPLDVVKTRFQLEVTTPTAAAVGKQVERYNGVIDCLKKIVKKEGFSRLYRGISSPMLMEAPKRATKFACNDQYQKIFKNLFNTNETTQKISIAAGASAGMTEAAVIVPFELIKIRMQDVK---SSYLGPMDCLKKTIKNE--GIMGLYKGIESTMWRNALWNGGYFGVIYQVRNSMPVAKTKGQKTRNDLIAGAIGGTVGTMLNTPFDVVKSRIQSVDAVSSAVKKYNWCLPSLLVIYREEGFRALYKGFVPKVCRLAPGGSLMLVVFTGMMNFFRDLKYGH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : *. :*. :*: *: : ********:*:: . * ..: : : **: ::** .*: *:***. ** : : : : : . :* :. *: : ***::*: * : . .. : *::: *: ** :*: : : *:.::: :**. ::: :* : : ... . :..::. ... .:*:.*.***. :.* . :* *. : :: ::***: :*:**: . : *:.***.::*:.: :: ", "identical_positions": 61, "similar_positions": 110, "identity": "19.43%" }, { "cls_id": "homologset.agr.SGD:S000005750", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V678-1", "uniprot_id": "G3V678_RAT", "id": "G3V678-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC3", "aln": "----MAGILFEDIFDVKDIDPEGKKFDRVSRLHCESE-SFKMDLILDVNIQIYPVDLGDKFRLVIASTLYEDGTLDDGE------YNPTDDRPSRADQFEYVMYGKVYRIEGDETSTEAATRLSAYVSYGGLLMRLQGDANNLHGFEVDSRVYLLMKKLAF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q923G2-1", "uniprot_id": "RPAB3_MOUSE", "id": "Q923G2-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC3", "aln": "----MAGILFEDIFDVKDIDPEGKKFDRVSRLHCESE-SFKMDLILDVNIQIYPVDLGDKFRLVIASTLYEDGTLDDGE------YNPTDDRPSRADQFEYVMYGKVYRIEGDETSTEAATRLSAYVSYGGLLMRLQGDANNLHGFEVDSRVYLLMKKLAF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52434-1", "uniprot_id": "RPAB3_HUMAN", "id": "P52434-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC3", "aln": "----MAGILFEDIFDVKDIDPEGKKFDRVSRLHCESE-SFKMDLILDVNIQIYPVDLGDKFRLVIASTLYEDGTLDDGE------YNPTDDRPSRADQFEYVMYGKVYRIEGDETSTEAATRLSAYVSYGGLLMRLQGDANNLHGFEVDSRVYLLMKKLAF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AXL7-1", "uniprot_id": "A0A8I6AXL7_RAT", "id": "A0A8I6AXL7-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC3", "aln": "MHFMTAGILFEDIFDVKDIDPEGKKFDRVSQLHCESE-SFKVDLILDINIQIYPVDLGDKFRLVIASTLYDDDTLDDGE------YNPTDGRPSRADQFEYVMYGKVYRIEGDESSTEAATCLSACVSYGGLLMRPQGDANNLHEFEVDSRVYLLKKKLAF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VNZ3-1", "uniprot_id": "Q9VNZ3_DROME", "id": "Q9VNZ3-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC3", "aln": "----MAGVLFEDIFNVKDMDPEGKKFDRVSRLHCESE-SFKMDLILDINSWLYPMELGDKFRLVLATTLREDGCPDSGE------YNPMEHEGTRADSFEYVMYGKIYRIEGDEAHNEAS-RLSAYVSFGGLLMRLQGDANNLHGFEVDQHMYLLMKRLAF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20436-1", "uniprot_id": "RPAB3_YEAST", "id": "P20436-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC3", "aln": "----MSNTLFDDIFQVSEVDPG--RYNKVCRIEAASTTQDQCKLTLDINVELFPVAAQDSLTVTIASSLNLEDTPANDSSATRSWRPPQAGDRSLADDYDYVMYGTAYKFEEVS-----KDLIAVYYSFGGLLMRLEGNYRNLNNLKQEN-AYLLIRR---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. **:***:*.::** ::::*.::.. * . : .* **:* ::*: *.: :.:*::* :. ... * : **.::*****. *::* . ::. *:****** :*: .**: :: :. *** :: ", "identical_positions": 41, "similar_positions": 57, "identity": "25.47%" }, { "cls_id": "homologset.agr.SGD:S000005752", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RZ79-1", "uniprot_id": "B2RZ79_RAT", "id": "B2RZ79-1", "name": "Iron-sulfur cluster assembly enzyme ISCU", "aln": "-MAAAGAGRLRRAASALLLRSPRLPARELSAPARLYHKKVVDHYENPRNVGSLDKTSKNVGTGLVGAPACGDVMKLQIQVDEK-GKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTIKNTDIAKELCLPPVKLHCSMLAEDAIKAALADYKLKQEAKKDEPEKQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D7P6-1", "uniprot_id": "ISCU_MOUSE", "id": "Q9D7P6-1", "name": "Iron-sulfur cluster assembly enzyme ISCU", "aln": "MAAATGAGRLRRAASALLLRSPRLPARELSAPARLYHKKVVDHYENPRNVGSLDKTSKNVGTGLVGAPACGDVMKLQIQVDEK-GKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTIKNTDIAKELCLPPVKLHCSMLAEDAIKAALADYKLKQESKKEEPEKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1K1-1", "uniprot_id": "ISCU_HUMAN", "id": "Q9H1K1-1", "name": "Iron-sulfur cluster assembly enzyme ISCU", "aln": "-MAAAGAFRLRRAASALLLRSPRLPARELSAPARLYHKKVVDHYENPRNVGSLDKTSKNVGTGLVGAPACGDVMKLQIQVDEK-GKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTIKNTDIAKELCLPPVKLHCSMLAEDAIKAALADYKLKQEPKKGEAEKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHK6-1", "uniprot_id": "ISCU_DROME", "id": "Q9VHK6-1", "name": "Iron-sulfur cluster assembly enzyme IscU", "aln": "-------MSLVRNSSR-LLRS--QLKRVQSVPVALYHENVVEHYENPRNVGSLDKKDVTVGTGLVGAPACGDVMKLQIKVDEN-GKIVDAKFKTFGCGSAIASSSLATEWVKGKSIDEAGKLKNTDIAKELRLPPVKLHCSMLAEDAIKAALADYKVKQQKKVAN----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12056-1", "uniprot_id": "ISU2_YEAST", "id": "Q12056-1", "name": "Iron sulfur cluster assembly protein 2, mitochondrial", "aln": "--------MFARLANPAHFKP-LTGSHITRAAKRLYHPKVIDHYTNPRNVGSMDKSLANVGTGIVGAPACGDVIKLQIQVNDKSGIIENVKFKTFGCGSAIASSSYMTELVRGMSLDEAVKIKNTEIAKELSLPPVKLHCSMLAEDAIKAAIKDYKTKRNPSVLH----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :. ::. : .. *** :*::** *******:**. .****:*********:****:*::: * * :.:************** ** *:* :::** .:***:***** *******************: *** *:: . . ", "identical_positions": 87, "similar_positions": 36, "identity": "51.48%" }, { "cls_id": "homologset.agr.SGD:S000005757", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62862-1", "uniprot_id": "MP2K5_RAT", "id": "Q62862-1", "name": "Dual specificity mitogen-activated protein kinase kinase 5", "aln": "------------------MLWLALGPFRAMENQVLVIR-----------------------------IKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRAGPSQHTSPVVSDSLPSNSLKKSSAELRKILANGQMNE---------QDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVI-LLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVE--NRISICTEFMDGGSLDVYRK--------IPEHVLGRIAVAVVKGLTYLWS-LKILHRDVKPSNMLVNTSGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYP-------------------QIQKNQGSLMPLQLLQCIVDEDSPVLPLG----EFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNATVVSMWVCRALEERRSQQGPP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVS7-1", "uniprot_id": "MP2K5_MOUSE", "id": "Q9WVS7-1", "name": "Dual specificity mitogen-activated protein kinase kinase 5", "aln": "------------------MLWLALGPFCAMENQVLVIR-----------------------------IKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRAGPSQHTSPVVSDSLPSNSLKKSSAELRKILANGQMNE---------QDIRYRDTLGHGNGGTVYKAHHVPSGKILAVKVI-LLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVE--NRISICTEFMDGGSLDVYRK--------IPEHVLGRIAVAVVKGLTYLWS-LKILHRDVKPSNMLVNTGGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYP-------------------QIQKNQGSLMPLQLLQCIVDEDSPVLPLG----EFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNSTVVSMWVCRALEERRSQQGPP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13163-1", "uniprot_id": "MP2K5_HUMAN", "id": "Q13163-1", "name": "Dual specificity mitogen-activated protein kinase kinase 5", "aln": "------------------MLWLALGPFPAMENQVLVIR-----------------------------IKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNE---------QDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVI-LLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVE--NRISICTEFMDGGSLDVYRK--------MPEHVLGRIAVAVVKGLTYLWS-LKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYP-------------------QIQKNQGSLMPLQLLQCIVDEDSPVLPVG----EFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVSMWVCRALEERRSQQGPP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24324-1", "uniprot_id": "DSOR1_DROME", "id": "Q24324-1", "name": "Dual specificity mitogen-activated protein kinase kinase dSOR1", "aln": "-----------------------------MSKNKLNLV-----------------------------LPPVNTEATVAAATVAP--------------------------------------------------------------------TPPFKTPSGTDTHSLLGKPKTSIDALTETLEGLDMGDTERKRIKMFLSQKEKIGELSD---------EDLEKLGELGSGNGGVVMKVRHTHTHLIMARKLI-HLEVKPAIKKQILRELKVLHECNFPHIVGFYGAFYSD--GEISICMEYMDGGSLDLILKRAG----RIPESILGRITLAVLKGLSYLRDNHAIIHRDVKPSNILVNSSGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPNTATLESIFADNAEESGQPTDEPRAMAIFELLDYIVNEPPPKLEHK----IFSTEFKDFVDICLKKQPDERADLKTLLSHPWIRKA-ELEEVDISGWVCKTMDLPPSTPKRNTSPN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32490-1", "uniprot_id": "MKK1_YEAST", "id": "P32490-1", "name": "MAP kinase kinase MKK1/SSP32", "aln": "MASLFRPPESAKCNPNSPRLKLPLLRNNQVDENNIYLTSNGSSTTAYSSHTPEPLTSSTSTLFSQTRLHPSDSSMTLNTMKKRPAPPSLPSLSINSQSKCKTLPELVPIADVSDGKHDLGLKQRVIAENELSGNSDLTPSSMASPFSHTNTSSPYLRNDLSNSVGSDFSNLISAYEQSSSPIKSSSQPKSS-SESYIDLNSVRDVDQLDENGWKYANLKDRIETLGILGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHE-KKVIHRDIKPQNILLNENGQVKLCDFGVSGEAVNSLATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGKFPCS--------------------SEKMAANIAPFELLMWILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPRQMINHPWIKGQMKKN-VNMEKFVRKCWKD------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:: : : : :: . : * . : . . : :. . :.. . . ... .. * . .::.: : :. . ** * ** * * *:* *:* *: :***: **:. . : :*: :** * : . * *. *:*.* *** * :.* :**:*: **::**:** . ::***:**.*:*:* *::*:****** : ::*:*.::.** **:***:.* *.: **:****::::*:* * :* . . : ::** *: . :* * *: *::*:. **. . ::.**:* . : . :. :* : . ", "identical_positions": 93, "similar_positions": 121, "identity": "17.13%" }, { "cls_id": "homologset.agr.SGD:S000005758", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97576-1", "uniprot_id": "GRPE1_RAT", "id": "P97576-1", "name": "GrpE protein homolog 1, mitochondrial", "aln": "----MAAR-----CVRLARRSLPALALSFRPSPRLLCTATKQKNNGQNLEEDLGH-CEPKTDPSSADKTLLEEKVKLEEQLKETMEKYKRALADTENLRQRSQKLVEEAKLYGIQGFCKDLLEVADILEKATQSVPKE-EVSNNNPHLKSLYEGLVMTEVQIQKVFTKHGLLRLDPIGAKFDPYEHEALFHTPV-EGKEPGTVALVSKVGYKLHGRTLRPALVGVVKDA----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LP6-1", "uniprot_id": "GRPE1_MOUSE", "id": "Q99LP6-1", "name": "GrpE protein homolog 1, mitochondrial", "aln": "----MAAR-----CVRLARRSLPALALSFRPSPRLLCTATKQKNNGQNLDEDLGH-CEPKTDPPSADKTLLEEKAKLEEQLRETMEKYKRALADTENLRQRSQKLVEEAKLYGIQGFCKDLLEVADILEKATQSVPKE-EISNNNPHLKSLYEGLVMTEVQIQKVFTKHGLLRLDPIGAKFDPYEHEALFHTPV-EGKEPGTVALVSKVGYKLHGRTLRPALVGVVKDA----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HAV7-1", "uniprot_id": "GRPE1_HUMAN", "id": "Q9HAV7-1", "name": "GrpE protein homolog 1, mitochondrial", "aln": "----MAAQ-----CVRLARRSLPALALSLRPSPRLLCTATKQKNSGQNLEEDMGQ-SEQKADPPATEKTLLEEKVKLEEQLKETVEKYKRALADTENLRQRSQKLVEEAKLYGIQAFCKDLLEVADVLEKATQCVPKE-EIKDDNPHLKNLYEGLVMTEVQIQKVFTKHGLLKLNPVGAKFDPYEHEALFHTPV-EGKEPGTVALVSKVGYKLHGRTLRPALVGVVKEA----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88396-1", "uniprot_id": "GRPE2_MOUSE", "id": "O88396-1", "name": "GrpE protein homolog 2, mitochondrial", "aln": "----MAARSLWA-VQRLQRLLASGAMSESRGWLHPFSTATQRTAGEDCSSEDP----PDGLGPSLAEQALRLKAVKLEKEVQDLTLRYQRAVADCENIRRRTQRCVEDAKIFGIQSFCKDLVEVADILEKTAKCCSEGAEPEDHRRTLEKVFQGLSLLEARLKSVFTKHGLEKMTPIGDKYDPHEHELICHMPAGVGVQPGTVALVRQDGYKLHGRTIRLAQVEVAVESQRRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZVY3-1", "uniprot_id": "A0A8I5ZVY3_RAT", "id": "A0A8I5ZVY3-1", "name": "GrpE protein homolog", "aln": "----MAARSLWA-VQRLQRLLASGAVSESRGWLHPFSTATQRTAGEDCSSEDP----PDGLGPSLAEQALRLKAVKLEKEVQDLTLRYQRAVADCENIRRRTQRCVEDAKIFGIQSFCKDLVEVADILEKTAECFSDGAEPQDHKLTLEKVFQGLSLLEAKLKSVFTKHGLEKMAPIGDKYDPHEHELICHMPAGVGVQPGTVALVRQDGYKLHGRTIRLAQVEVAVESQRRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TAA5-1", "uniprot_id": "GRPE2_HUMAN", "id": "Q8TAA5-1", "name": "GrpE protein homolog 2, mitochondrial", "aln": "----MAVRSLWAGRLRVQRLLAWSAAWESKGWPLPFSTATQRTAGEDCRSEDP----PDELGPPLAERALRVKAVKLEKEVQDLTVRYQRAIADCENIRRRTQRCVEDAKIFGIQSFCKDLVEVADILEKTTECISEESEPEDQKLTLEKVFRGLLLLEAKLKSVFAKHGLEKLTPIGDKYDPHEHELICHVPAGVGVQPGTVALVRQDGYKLHGRTIRLARVEVAVESQRRL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48604-1", "uniprot_id": "GRPE_DROME", "id": "P48604-1", "name": "GrpE protein homolog, mitochondrial", "aln": "----MSAK------AALPLQMFGRRLVHLRSSVTSQNMSALRLYSTEKQPEEAT--EQKATESSPEVEKLTKELAAAKEQNAELMDKYKRSLADSENMRNRLNKQISDAKIFGIQSFCKDLLEVADTLGHATQAVPKD--KLSGNADLKNLYEGLTMTRASLLQVFKRHGLEPLDPINQKFDPNQHEALFQKED-KTVEPNTVVEVTKLGYKLHERCIRPALVGVSKC-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38523-1", "uniprot_id": "GRPE_YEAST", "id": "P38523-1", "name": "GrpE protein homolog, mitochondrial", "aln": "MRAFSAATVRATTRKSFIPMAPRTPFVTPSFTKNVGSMRRMRFYSDEAKSEESKENNEDLTEEQSEIKKLESQLSAKTKEASELKDRLLRSVADFRNLQQVTKKDIQKAKDFALQKFAKDLLESVDNFGHALNAFKEE--DLQKSKEISDLYTGVRMTRDVFENTLRKHGIEKLDPLGEPFDPNKHEATFELPQ-PDKEPGTVFHVQQLGFTLNDRVIRPAKVGIVKGEEN--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . : . : *: . * : :: : : *::** .*::. :: :..** :.:* *.***:* .* : :: :. . . :..:: *: : . : ..: :**: : *:. :** :** . :*.** * : *:.*: * :* * * : ", "identical_positions": 33, "similar_positions": 65, "identity": "14.16%" }, { "cls_id": "homologset.agr.SGD:S000005759", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88866-1", "uniprot_id": "HUNK_MOUSE", "id": "O88866-1", "name": "Hormonally up-regulated neu tumor-associated kinase", "aln": "----MPAAAGDG---------------------------LLGEPAAPGGDGGAEDTTRPAAACEGSFLPAWVS-------------------------------------------------GVSRERLRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTG-----EKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLDEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLA-RKKYG-PKIDVWSIGVNMYAMLTGTLPFTVEPF-----SLRALYQKMVDKAMNPLPTQLSTGAVNFLRSLLEPDPVKRPNIQQALANRWLNENYTGKVPCNVTYPNRISLEDLSPS--VVLHMTEKLGYKNSDVINTVLSNRACHILAIYFLLNKKLERYLS-----GKSDIQDSICYKTQLYQIEKCRATKEPYEASLDTWTRDFEFHAVQDKKPKEQEKRGDFLHR-----------------------PFSKKLDKN-----------------------------LPSHKQPSPS-------------------------------------------------------------------------LITQLQSTKALLKD-----------------------------------------------------RKASKSGFPDKDSFVCRNLFRKTSDSNCVASSSMEFIPVPPPRTPRIVKKLEPHQPG-----------------------------------------PGSASILPK-----------------EEPLLLDMVRSFESVDREDHIELLSPSHHYRILS-----------------------------------------------------------SPVSLARRNSSERTLS---------------------------------------------------------------QGLLSGS------------------------TSPLQTPLHSTLVSFAHEEKNSPPKEE--------------------------------------------------------------------------GVCSPPPVPS------------NGLLQPLGSPNCVKSRGRFPMMGIGQMLRKRHQSLQPSSE--------------RSLDASMSPLQPTAPS-------------------------------------------SLSFDMADGVKGQC--------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZV60-1", "uniprot_id": "A0A8I5ZV60_RAT", "id": "A0A8I5ZV60-1", "name": "Hormonally up-regulated neu tumor-associated kinase", "aln": "----MPAAAGDG---------------------------LLGEPAAPGGDGGAEDTARPAAACEGSFLPAWVS-------------------------------------------------GVSRERLRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTG-----EKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLDEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLA-RKKYG-PKIDVWSIGVNMYAMLTGTLPFTVEPF-----SLRALYQKMVDKEMNPLPTQLSTGAINFLRSLLEPDPVKRPNIQQALANRWLNENYTGKVPCNVTYPNRISLEDLSPS--VVLHMTEKLGYKNSDVINTVLSNRACHILAIYFLLNKKLERYLS-----GKSDIQDSICYKTQLYQIEKCRATKEPYEASLDTWTKDFELHAVQDKKPKEQDKRADFLHR-----------------------PFSKKLDKS-----------------------------LPSHKQPSPS-------------------------------------------------------------------------LITQIQNTKALLKD-----------------------------------------------------RKASKSGFGDKDSFGCRNLFRKTSDSNCVASSSMEFIPVPPPRTPRIVKKQEPHQPG-----------------------------------------PGSASMLPK-----------------EEPLLLDMVRSFESVDREDHIELLSSSHHYRILS-----------------------------------------------------------SPVSLARRNSGERTLS---------------------------------------------------------------PGLLSGS------------------------TSPLQTPLHSTLVSFTHEEKNSPPKEE--------------------------------------------------------------------------GVCSPPPVPS------------NGLMQPLGSPNCVKSRGRFPMMGIGQMLRKRHQSLQPSSE--------------RSLEVSMSPLQPTAPS-------------------------------------------SLSFDMADGVKGQC--------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57058-1", "uniprot_id": "HUNK_HUMAN", "id": "P57058-1", "name": "Hormonally up-regulated neu tumor-associated kinase", "aln": "----MPAAAGDG---------------------------LLGEPAAPGGGGGAEDAARPAAACEGSFLPAWVS-------------------------------------------------GVPRERLRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTG-----EKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLA-RKKYG-PKIDVWSIGVNMYAMLTGTLPFTVEPF-----SLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQALANRWLNENYTGKVPCNVTYPNRISLEDLSPS--VVLHMTEKLGYKNSDVINTVLSNRACHILAIYFLLNKKLERYLS-----GKSDIQDSLCYKTRLYQIEKYRAPKESYEASLDTWTRDLEFHAVQDKKPKEQEKRGDFLHR-----------------------PFSKKLDKN-----------------------------LPSHKQPSGS-------------------------------------------------------------------------LMTQIQNTKALLKD-----------------------------------------------------RKASKSSFPDKDSFGCRNIFRKTSDSNCVASSSMEFIPVPPPRTPRIVKKPEPHQPG-----------------------------------------PGSTGIPHK-----------------EDPLMLDMVRSFESVDRDDHVEVLSPSHHYRILN-----------------------------------------------------------SPVSLARRNSSERTLS---------------------------------------------------------------PGLPSGS------------------------MSPLHTPLHPTLVSFAHEDKNSPPKEE--------------------------------------------------------------------------GLCCPPPVPS------------NGPMQPLGSPNCVKSRGRFPMMGIGQMLRKRHQSLQPSAD--------------RPLEASLPPLQPLAPV-------------------------------------------NLAFDMADGVKTQC--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W532-1", "uniprot_id": "Q9W532_DROME", "id": "Q9W532-1", "name": "non-specific serine/threonine protein kinase", "aln": "MSTCEAAAAGENGSQAKSEESQPPEDQKKKQPQHERNEKQLDKPPENLPQNGKTEAKGAEGACSHPPLDALRSSVLLDAGAASPSIDAIVACKDALLAQKLFASGGGSTPGPSPTSSAVGAGGISGKDLLKLKEPMRVGFYDIER-TIGKGNFAVVKLARHRITK-----NEVAIKIIDK--SQLDQTNLQKVYREVEIMKRLKHPHIIKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIISAVEYCHKKGIVHRDLKAENLLLDLNMNIKIADFGFS---NHFKPGELLATWCGSPPYAAPEVFE-GKQYTGPEIDIWSLGVVLYVLVCGALPFDGS-------TLQSLRDRVLSGRFR-IPFFMSSECEHLIRRMLVLEPTRRYTIDQIKRHRWMCPELLEHVLIAKYNLGAERQTSVEPSEDILRIMAEYVGIGSDKTRASLKKNTYDHVAAIYLLLQDRVSHKKEQSNGLGASALASSTSASRMIYSSRNDHQPTQQQSQQQSKTISTSSILAKDQCHKRLSRHQTVLMSERNAHAGATPTVPDPGPGYYAKYGPLQLPLPLTGHSHLTGYLNGGGVEVDASGIPLPMRYTPLPTAASPAPSNCSSTSSRVGRHSLSSSSPRSHRPVAISLSIDNNPSLANLRCREMMEAGGGPVGAVGVPLASKQLHQTISEFIIKQSTEDCRALLQQSTAVAEGKDDPPKAESSVGGVPPPASTTPTSSTAGPESGSAPCPGEINGKTIKTMSSSSSFDSKANLGQSFRYKMSAEASKLFQTLQESPLPVEQRTKRRVHVGSTNGSGGDSGQETNDAKSNGDSRSEKKVLAQGSSSTDEGCETDQGNDPGSASQESKGSNGGGSGNANGGPTSHSSSDLTRLVGTTTSGQSHKMRSYASSSSSSGVLAGSAGSYSKSLSQNLSRGSSKSNCSGPYDSLDFALPSGKGSLPSCMGSSSMLATPTPASASPAGISSEHSSERSLYGSHNSCIHMPGALPLGLGLPQSSASTPTPNPTPPPNGGGVTFLDKRSPIHFREGRRASDGLVAQGLLSSGSLLGTSRVYGSYRYEQAKRHGWLEIQQLQQLQQEAAVGHSHPHAHQHPHQHPHPHPQAYGLEELCQFPNGQFYALPGKHHPLLTLPHHHAHPAQHHHGHHSLFHSGHQATPLLLEAAAGGDMYGHGCYAPPPPPPGLYTHHQLGVGMAVPMSPMQKPPLQQQLLQHRLLQQKRQLFQKQYALEAQLAGRHHHHQQHSHHHHHHFGHSLGPPPPPAPAPEHHLADELYELALLDRPRSGTPRLQHSMTMPGAHAFSQMNLKTSYISQSDQVPGAAPNGAGSGGSAAGVSCSAPPSTAPGTPTVKCKPTTPHGHSLDSDYHTSTPVLSLFTPNWQSLVKPLSESPILEISEHLESV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q01919-1", "uniprot_id": "KIN4_YEAST", "id": "Q01919-1", "name": "Serine/threonine-protein kinase KIN4", "aln": "----MASVPKR----------------------------------HTYGGNVVTDRDRHSLQRNNEILHPIHK---------------------------------------------------------NQRKHATFGPYIIGS-TLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVN--EFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQTPLK-FPEYITPIPRDLLRRILVPNPRRRINLQTIKRHVWLKPHEAFLSIQPNYWDEHLQKERPKPP--NKGDVGRHSTYSSSASSYSKSRDRNSLIIESTLEQHRMSPQLAT-----SRPASPTFSTGSKVVLNDTKNDMKESNINGERTSASCRYTRDSKGNGQTQIEQVSARHSSRGN------------------KHTSVAGLVTIPG--------------------------SPTTARTRNAPSS-----------------------------------------------------------------------KLTEHVKDSSQTSFT---------------------------------------------------QEEFHRIGNYHVPRSRPRPTSYYPGLSRNTADNSLADIPVNKLGSNGRLTDAKDPVPLN-------------------------------------AIHDTNKATISNN------------------SIMLLSEGPAAKTSPVDYHYAIGDLNHGDKPIT-----------------------------------------------------------EVIDKINKDLTHKAAEN---------------------------------------------------------------GFPRES----------------------IDPESTSTILVTKEPTNSTDEDHVESQLEN------------------------------------------------------------------------VGHSSNKSDAS-----------------SDKDSKKIYEKKRFSFMSLYSSLNGSRSTVESRTS--------------KGNAPPVSSRNPSGQSNRSNIKITQ----------------------------------QQPRNLSDRVPNPDKKINDNRIRDNAPSYAE--SENPGRSVRASVMVSTLREENRSELSNEGNNVEAQTSTARKVLNFFKRRSMRV--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:.. . : . * . . . :. .* * * .:*:*.*. *: . : ::****:* : : * :: ** : : : **:* * ::::..: :* * . *:: . * . *:.*: * : *:**.*:: * *:****** ****** . *: : ***: : .: : * **** *****:. * * : *:** ** :*.:: * **: . : * . : . :. :* ::. ::* :* :* :* .:: : *: . .*. : . .. : : : : : : . . . : . : . . . . : : : : . . .. : .: : * : :. ..: . : . . .: : . * .. .. . ...: : . : : : . . . : . . .. .:: *: . . : . : .: . * . . .. . .. . :. :: * : :::. : .: . * . . :* * ", "identical_positions": 86, "similar_positions": 199, "identity": "6.06%" }, { "cls_id": "homologset.agr.SGD:S000005760", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55142-1", "uniprot_id": "RL35A_MOUSE", "id": "O55142-1", "name": "Large ribosomal subunit protein eL33", "aln": "------------------------------------------------------------------------------------MSGRLWCKAIFAGYKRGLRNQREHTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRV--IWGKVTRAHGNSGMVRAKFRSNLPAKAIGHRIRVMLYPSRI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GLI9-1", "uniprot_id": "A0A8I6GLI9_RAT", "id": "A0A8I6GLI9-1", "name": "Large ribosomal subunit protein eL33", "aln": "MRDERKEKNRKTKRRDKKSKVFERGLAESSLSLTFAFWRSTSGLSVERGGACIPQGRAAGLAFLFPPSWRLWRPAGNRTSKKTSMSGRLWCKAIFAGYKRGLRNQREHTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRV--IWGKVTRAHGNSGMVRAKFRSNLPAKAIGHRIRVMLYPSRI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18077-1", "uniprot_id": "RL35A_HUMAN", "id": "P18077-1", "name": "Large ribosomal subunit protein eL33", "aln": "------------------------------------------------------------------------------------MSGRLWSKAIFAGYKRGLRNQREHTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRV--IWGKVTRAHGNSGMVRAKFRSNLPAKAIGHRIRVMLYPSRI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8L2QJQ6-1", "uniprot_id": "A0A8L2QJQ6_RAT", "id": "A0A8L2QJQ6-1", "name": "Large ribosomal subunit protein eL33", "aln": "------------------------------------------------------------------------------------MSGRLWCKAIFAGYKPGLLNQREYTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRV--IWGKVTRAHGNSGVVRAKFQSNLPAKAIGHRIRVMLYPSQI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VNB9-1", "uniprot_id": "Q9VNB9_DROME", "id": "Q9VNB9-1", "name": "Large ribosomal subunit protein eL33", "aln": "---------------------------------------MADTQAKSTTAPKAAKAQKAPKAVKAPKAEKPAASEAKVSAKKYKRHGRLFAKAVFTGYKRGLRNQHENQAILKIEGARRKEHGSFYVGKRCVYVYKAETKKCVPQHPERKTRVRAVWGKVTRIHGNTGAVRARFNRNLPGHAMGHRIRIMLYPSRI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41056-1", "uniprot_id": "RL33B_YEAST", "id": "P41056-1", "name": "Large ribosomal subunit protein eL33B", "aln": "----------------------------------------------------------------------------------MAESHRLYVKGKHLSYQRSKRVNNPNVSLIKIEGVATPQEAQFYLGKRIAYVYRAS--KEVRG---SKIRV--MWGKVTRTHGNSGVVRATFRNNLPAKTFGASVRIFLYPSNI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: *. . .*: . :. :::****. :. .**:*** .***:*. . . * ** :****** ***:* *** *. ***.:::* :*::****.*", "identical_positions": 44, "similar_positions": 32, "identity": "22.45%" }, { "cls_id": "homologset.agr.SGD:S000005762", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920D2-1", "uniprot_id": "DYR_RAT", "id": "Q920D2-1", "name": "Dihydrofolate reductase", "aln": "--------MVRPLNCIVAVSQNMGIGKNGDLPWPLLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINIVLSRELKEP----PQGAHFLAKSLDDALKLIEQPELASKVDMVWVVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLEKYKLLPE--YPGVLSEIQ-----------------EEKGIKYKFEVYEKKD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00375-1", "uniprot_id": "DYR_MOUSE", "id": "P00375-1", "name": "Dihydrofolate reductase", "aln": "--------MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINIVLSRELKEP----PRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPE--YPGVLSEVQ-----------------EEKGIKYKFEVYEKKD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00374-1", "uniprot_id": "DYR_HUMAN", "id": "P00374-1", "name": "Dihydrofolate reductase", "aln": "--------MVGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEP----PQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPE--YPGVLSDVQ-----------------EEKGIKYKFEVYEKND-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86XF0-1", "uniprot_id": "DYR2_HUMAN", "id": "Q86XF0-1", "name": "Dihydrofolate reductase 2, mitochondrial", "aln": "--------MFLLLNCIVAVSQNMGIGKNGDLPRPPLRNEFRYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINLVLSRELKEP----PQGAHFLARSLDDALKLTERPELANKVDMIWIVGGSSVYKEAMNHLGHLKLFVTRIMQDFESDTFFSEIDLEKYKLLPE--YPGVLSDVQ-----------------EGKHIKYKFEVCEKDD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LWC6-1", "uniprot_id": "Q1LWC6_DANRE", "id": "Q1LWC6-1", "name": "dihydrofolate reductase", "aln": "MMNIEGEEMRKPIRLIAAACRDMGIGKDGQIPWC-LPKEFQFLLDTITAVSAPGKKNLIVWGRICWFSCPETVFPLANCINLVLSRKMISV----PPHAHYLCKDFDSIIRLVSEPPLCHTVEVIWILGGTEVYKESLEHPWCDLIYLTDIMANFECDVFFPEFDPNIFRKQKS--FPGVPDEII-----------------EENGIKFQFQVFKKIKN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P17719-1", "uniprot_id": "DYR_DROME", "id": "P17719-1", "name": "Dihydrofolate reductase", "aln": "--------MLR-FNLIVAVCENFGIGIRGDLPWR-IKSELKYFSRTTKRTSDPTKQNAVVMGRKTYFGVPESKRPLPDRLNIVLSTTLQESD---LPKGVLLCPNLETAMKILEEQ---NEVENIWIVGGSGVYEEAMASPRCHRLYITKIMQKFDCDTFFPAIP-DSFREVAP--DSDMPLGVQ-----------------EENGIKFEYKILEKHS-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07807-1", "uniprot_id": "DYR_YEAST", "id": "P07807-1", "name": "Dihydrofolate reductase", "aln": "----MAGGKIPIVGIVACLQPEMGIGFRGGLPWR-LPSEMKYFRQVTSLTKDPNKKNALIMGRKTWESIPPKFRPLPNRMNVIISRSFKDDFVHDKERSIVQSNSLANAIMNLESN-FKEHLERIYVIGGGEVYSQIFSITDHWLITKINPLDKNATPAMDTFLDAKKLEEVFSEQDPAQLKEFLPPKVELPETDCDQRYSLEEKGYCFEFTLYNRK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.. ::*** * :* : .*:::: . . *:* :: *: : . * . ** . :*:::* : . . . .: : . :: ::::** **.: : : : . .: . : . . . * : ::: : :: ", "identical_positions": 19, "similar_positions": 61, "identity": "8.68%" }, { "cls_id": "homologset.agr.SGD:S000005763", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "S4R1M9-1", "uniprot_id": "OSB10_MOUSE", "id": "S4R1M9-1", "name": "Oxysterol-binding protein-related protein 10", "aln": "MERAAQSTDGGGGGGSNSSSRSSSRATSAGSSPSCSLAGRGVASRSGAAGLGGGGSRSSP-GSVAASPSGGGGRRREPALEGVLSKYTNLLQGWQSRYFVLDFEAGLLQYFVNEQSKHQKPRGVLSLSGAIVSLSDEAPHMLVVYSANGEMYKLRAADSKEKQLWVTQLRACAKYHMEMSSKTTPGSRSRSLTLLPHGTPSSASPCSQRHLSTGAPGVVSVTRHKSPAAARRAKSQYSGQLHEVREMMNQVEGQQKNLVHAIESLPGSGPLTALDQDLLLLKATSAATLSCLGECLSLLQQSVRQAAPPSHKPGASETILGWHGPTSHSTDQLKNGTLGSLPSASANITWAILPNSAEEEHNSQPEPEPDSGPELVLSEEEQSDNEDKGEVEPGAMEDQRSVILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVISFVEYYLTAFHEGRKGTLAKKPYNPIIGETFHCSWEVPKDRVKS--KWTSPHPPISAHEHPMADDPSKS----YKLRFVAEQVSHHPPISCFYCECKEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLDHGEEYVFTLPSAYARSILTVPWVELGGKVNISCAKTGYSATVTFHTKPFYGGKVHRVTAEVKHNPTNTIVCKAHGEWNGTLEFTYSNGETKVIDTTTLPVYPKKLRPLEKQGPMESRNLWQEVTHYLRLGDIDAATEQKRRLEERQRVEERKR-ETLRTPWRPKYFIPEGD------GWVYFNPLWKTH--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LWM8-1", "uniprot_id": "F1LWM8_RAT", "id": "F1LWM8-1", "name": "Oxysterol-binding protein", "aln": "MERAAQSADGGGGGGSNSSSRSSSRATSAGSSPSCSLAGRGVASRSGAAGLGGGGSRSSP-GSVAASPSGGGGRRREPALEGVLSKYTNLLQGWQNRYFVLDFEAGLLQYFVNEQSKHQKPRGVLSLSGAIVSLSDEAPHMLVVYSANGEMYKLRAADSREKQLWVTQLRACAKYHMETSSKTTPGSRSRSLTLLPHGTPSSASPCSQRHLSAGAPGVVSVTRHKSPAAARRAKSQYSGQLHEVREMMNQVEGQQKNLVHAIESLPGSGPLTALDQDLLLLKATSAATLSCLGECLTLLQQSVRQAGPPSHKPGASESILGWHGPTSQSTDQLKNGTLGSLPSASANITWAILPNSAEEEHSSQPEPEPDSGPELVLSEEEQSDHEDKGEVEPGTVEDQHSVILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVISFVEYYLTAFHEGRKGTLAKKPYNPIIGETFHCSWEVPKDRVKS--KWTSPHPPISCHEHPMADDPSKS----YKLRFVAEQVSHHPPISCFYCECKEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLDHGEEYVFTLPSAYARSILTVPWVELGGKVNISCAKTGYSATVTFHTKPFYGGKVHRVTAEVKHNPTNTIVCKAHGEWNGTLEFTYSNGETKVIDTTTLPVYPKKLRPLEKQGPMESRNLWQEVTHYLRLGDIDAATEQKRRLEEKQRTEERKR-ETLRTPWRPKYFIPEGD------GWVYFNPLWKTH--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CI95-1", "uniprot_id": "OSB11_MOUSE", "id": "Q8CI95-1", "name": "Oxysterol-binding protein-related protein 11", "aln": "MQ---------GGEPASVMKVSESEGKLEGLATAVTPN-----KNSGNSSCGGAISSSSSNSSRGGSAKGWQYSDHMESVNGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSGN----SPISQRRPSQNAMSFFNVGHSKLQSVNKRAH-LHPDHLVEVREMMSHAEGQQRDLIRRIECLPASGLLSSLDQDLLMLKATSMATMNCLNDCFHILQL---QHASHQKGALPSGTTIEWLEPKIPLSNHYKNGAEQPFATEPN------KPMGAPEAQCVAESGVLAREPEDISADDEVEDTCDNKEDDLGAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIGITNGATPEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWRMPKSEVASGVSSSSSTPAITDHAPLPEEAPTQSVSDCYTVRFVAEQVSHHPPVSGFYAECAERKMCVNAHVWTKSKFLGMSIGVTMVGEGVLCLLEHGEEYTFSLPCAYARSILTVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKYNLTNTVVCRVQGEWNSVLEFTYSNGETKFVDLAKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKRSLEERQRTEERLR-TETGTPWKTKYFIKEGD------GWVYHKPLWKGIPSQPAE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8BX94-1", "uniprot_id": "OSBL2_MOUSE", "id": "Q8BX94-1", "name": "Oxysterol-binding protein-related protein 2", "aln": "------------------------------------------------------------MNGEEEFFDAVTGFDSDNSSIGEFSEAN-KISGMIDLDTSKSTRSGKNGEKPQQENGIQKHR--TALPAPMFTRSDFSVWSILKKCIGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHKAS----------------------SQSQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHPPISAFYSEGLNQDFRFHGSIYPKLKFWGKSVEAEPR--------------------------------------------------------------------------------------------GTITLELLKHNEAYTWTNPTCCVHNVILGQLWIEQYGIVEIVNHRTGDKCILHFKPCGLFGKELHR----------VEGYIQDKNRKKLFIMYGKWTECLWGIDPASYES---------------------------------FKKQEKRGDQARKAKMDDGPEK---------------------------------ANSDVPGDVADDVPVAQETVQV-IPGSKLLWRINSRPPNSAQMYNFTSFT--------------------------------VSLNELESGMEK--TLPPTDCRLRPDIRG---------------MENGNMDLASQEKERLEEKQREARKER-AKEDAEWRTRWFSPGNNPYTGAPDWLYAGHYFERNFSDCPDIY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AI28-1", "uniprot_id": "A0A8I6AI28_RAT", "id": "A0A8I6AI28-1", "name": "Oxysterol-binding protein", "aln": "------------------------------------------------------------MNGEEEFFDAVTGFDSDNS-TGEFSEAN-KITGMIDLDTSKSTRSGKHGERSPQENGIQKHR--TALPAPMFTRSDFSVWSILKKCIGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRAS----------------------NQSQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHPPISAFYSEGLNQDFMFHGSIYPKLKFWGKSVEAEPR--------------------------------------------------------------------------------------------GTITLELLKHNEAYTWTNPTCCVHNVILGQLWIEQYGIVEILNHRTGDKCILHFKPCGLFGKELHR----------VEGYIQDKNRKKLFIMYGKWTECLWGIDPVSYES---------------------------------FKKQEKRGDHARKAKSDDAPEK---------------------------------VNSDVPGNMADDVPVAQETVQV-IPGSKLLWRINSRPPNSAQMYNFTSFT--------------------------------VSLNELESGMEK--TLPPTDCRLRPDIRG---------------MENGNMDLASQEKERLEEKQREARKER-AKEEAEWRTR---PVHTSTVAVSIRTCTRRLIVSRWNHDK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H1P3-1", "uniprot_id": "OSBL2_HUMAN", "id": "Q9H1P3-1", "name": "Oxysterol-binding protein-related protein 2", "aln": "------------------------------------------------------------MNGEEEFFDAVTGFDSDNS-SGEFSEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKHR--TSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRAS----------------------CQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPR--------------------------------------------------------------------------------------------GTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHK----------VEGHIQDKNKKKLFMIYGKWTECLWGIDPVSYES---------------------------------FKKQERRGDHLRKAKLDEDSGK---------------------------------ADSDV----ADDVPVAQETVQV-IPGSKLLWRINTRPPNSAQMYNFTSFT--------------------------------VSLNELETGMEK--TLPPTDCRLRPDIRG---------------MENGNMDLASQEKERLEEKQREARRER-AKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4LGH8-1", "uniprot_id": "A0A0B4LGH8_DROME", "id": "A0A0B4LGH8-1", "name": "Oxysterol-binding protein", "aln": "--------------------------------------------------------------------------------------------------------------MAEGDYAEHVER--TELPATMISRKEVSIWAILKNCIGKDLSKITMPVMLNEPLSFLQRLCEYMEYAQLLTEAA----------------------QQEHPADRMKYVAAFAVSALASNWERLGKPFNPLLGETYELQKGD--YRIVCEQVSHHPPVSAFHAE--SKDFKFHGTISPKIKFWGKSVEVNPK--------------------------------------------------------------------------------------------GTVTVEFPKWNESYSWTNVNCCVHNIIVGRLWIEQYGKMEITNHATGHVASLTFKSAGSGAKNLHR----------VEGFVKDASETNLYFLYGKWTEFIKCCSAESYVQ---------------------------------FLKQGTRKNDDYDGSPNGTPKKMFSK-----------LNSFKLNSFRSLSIQDVSSDSYPPMEQEGDIPKSDSAYSLDIPDSTTLWSCKPRPSNCSEYYQFTHFA--------------------------------LQLNAMDSNMKPPLTLCPTDSRLRPDILH---------------LEEGNLDGASKEKTRLEEKQRHTRKQRKSTNSDDWSPRWFKYATNPHTKIDDWLYSGGYWDRKYDNTDTIF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35843-1", "uniprot_id": "HES1_YEAST", "id": "P35843-1", "name": "Oxysterol-binding protein homolog 5", "aln": "------------------------------------------------------------------------------------MSQHASSSSWTSFLKSISSFNGDLSSLSAPPFILSPTS----LTEFSQYWAEHPALFLEPSLIDGENYKDHCPFDPNVESKEVAQMLAVVRWFISTLRSQYCS-------------------RSESMGSEKKPLNPFLGEVFVGKWKNDE---HPEFGET----------VLLSEQVSHHPPMTAFSIFNEKNDVSVQGYNQIKTGFTKTLTLTVKP---------------------------------------------------------------------------------------------YGHVILKIKDETYLITTPPLHIEGILVASPFVELGGRSFIQSS-NGMLCVIEFSGRGYFTGKKNS----FKARIYRSPQEHSHKENALYLISGQWSGVSTIIKKDSQVS-------------------------------HQFYDSSETPTEHLLVKPIEEQHPLESR------------------------RAWKDVAEAIRQGNISMIKKTKEELENKQRALREQERVKGVEWQRRWFKQVDYMN--------------------------------ENTSNDVEKASEDDAFRKLASKLQLSVKN---------------VPSGTLIGGKDDKKDVSTALH-------------------------------WRFDKNLWMRENEITI---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : : . : * . : . . . . . .. : *. : . * :. .. . .:. . . . : ::: :* . : . : * . . .. : *: . * . . : . : : . : ::: : . : ....* :. : ", "identical_positions": 9, "similar_positions": 66, "identity": "1.14%" }, { "cls_id": "homologset.agr.SGD:S000005765", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GDZ5-1", "uniprot_id": "A0A8I6GDZ5_RAT", "id": "A0A8I6GDZ5-1", "name": "tRNA N(3)-cytidine methyltransferase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAA-------SLSEG-VPETE----------------------------------DRKRPQFGNRFLSDPARVFHHNAWDNVKWSEEQAAAAERKVQENSSQLVCPEKQADYEVNAHKYWDDFYKVHENGFFKDRHWLFTEFPELAPS----HDHLVNLHLEKQKNEVSKPRSSEDGPG-LAAEQH--KRPCTSHGCETRVPPVEEPVTQKLTHLEICADDFPGSSATYRILEVGCGVGNTVFPILQTN-NNPDLFVYCCDFSATAIELVKTNSEYDPSRCFAFVHDLCDEDQSYP--MPKDSLDVIVLIFVLSAIVPDKMQKAISKLSRLLKPGGVMLLRDYGRYDMAQLRFKKGQCLSGNFYVRGDGTRVYFFTQDELDTLFTAAGLEKVQNVVDRRLQVNRGKQLTMYRVWIQCKYSKPLVPSASQHVPTPHTT---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMK1-1", "uniprot_id": "METL2_MOUSE", "id": "Q8BMK1-1", "name": "tRNA N(3)-cytidine methyltransferase METTL2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAA-------SFPEG-VPETE----------------------------------DGKRPQFGHRFLSDPARVFHHNAWDNVKWSEEQAAAAERKVQENSSPLVCPEKQVDYEVNAHKYWDDFYRIHENGFFKDRHWLFTEFPELAPS----HSHLTGVPLEKQRSDVC-----EDGPG-LTAEQH--KCSCASPGCETQVPPLEEPVTQKLGHLEISGEEFPGSSATYRILEVGCGVGNTVFPILQTN-NNPNLFVYCCDFSATAIELLKTNSQYDPSRCYAFVHDLCDEDQSYP--VPEDSLDVIVLIFVLSAIVPDKMQKAISKLSRLLKPGGVMLLRDYGRYDMAQLRFKKGQCLSGNFYVRGDGTRVYFFTQGELDTLFTAAGLEKVQNLVDRRLQVNRGKQLTMYRVWIQCKYSKPLALRSSQHVPIPHATESSSHSGLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96IZ6-1", "uniprot_id": "MET2A_HUMAN", "id": "Q96IZ6-1", "name": "tRNA N(3)-cytidine methyltransferase METTL2A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAG-------SYPEG-APAVL----------------------------------ADKRQQFGSRFLRDPARVFHHNAWDNVEWSEEQAAAAERKVQENSIQRVCQEKQVDYEINAHKYWNDFYKIHENGFFKDRHWLFTEFPELAPSQN--QNHLKDWFLEN-KSEVPECRNNEDGPGLIMEEQH--KCSSKSLEHKTQTLPVEENVTQKISDLEICADEFPGSSATYRILEVGCGVGNTVFPILQTN-NDPGLFVYCCDFSSTAIELVQTNSEYDPSRCFAFVHDLCDEEKSYP--VPKGSLDIIILIFVLSAIVPDKMQKAINRLSRLLKPGGMMLLRDYGRYDMAQLRFKKGQCLSGNFYVRGDGTRVYFFTQEELDTLFTTAGLEKVQNLVDRRLQVNRGKQLTMYRVWIQCKYCKPLLSSTS------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P1Q9-1", "uniprot_id": "MET2B_HUMAN", "id": "Q6P1Q9-1", "name": "tRNA N(3)-cytidine methyltransferase METTL2B", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAG-------SYPEG-APAIL----------------------------------ADKRQQFGSRFLSDPARVFHHNAWDNVEWSEEQAAAAERKVQENSIQRVCQEKQVDYEINAHKYWNDFYKIHENGFFKDRHWLFTEFPELAPSQN--QNHLKDWFLEN-KSEVCECRNNEDGPGLIMEEQH--KCSSKSLEHKTQTPPVEENVTQKISDLEICADEFPGSSATYRILEVGCGVGNTVFPILQTN-NDPGLFVYCCDFSSTAIELVQTNSEYDPSRCFAFVHDLCDEEKSYP--VPKGSLDIIILIFVLSAVVPDKMQKAINRLSRLLKPGGMVLLRDYGRYDMAQLRFKKGQCLSGNFYVRGDGTRVYFFTQEELDTLFTTAGLEKVQNLVDRRLQVNRGKQLTMYRVWIQCKYCKPLLSSTS------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8KBL7-1", "uniprot_id": "MET2A_DANRE", "id": "A8KBL7-1", "name": "tRNA N(3)-cytidine methyltransferase METTL2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAPVVAADSPVIEN-MPETAGGATE-------------------------NSAEAQKRPQFGTRFLTDPRQVFQHNAWDNVEWSAEQEEAALKKVQENS-QPLPAEKQEEFDNRANEYWNDFYTIHENRFFKDRHWLFTEFPELAPQ----QKHLRG--AEEKES-------------------------------------LEHMLNGEDISLNPTHDEFPGASASYRILEVGCGVGNTVFPILKTN-NDPGLFVYCCDFSSTAVDLVKSNPEYDPSRCHAFVHDMSDESGEYP--MPDHSLDVIVLIFVLSALHPEKMQKSINRLGRLLKPGGVLLLRDYGRYDMAQLRFKKGRCLSENFYVRGDGTRVYFFTQDELHDLFSSAGLEKLQNLVDRRLQVNRGKQLTMYRVWVQCKYRKVLAPT--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9H825-1", "uniprot_id": "METL8_HUMAN", "id": "Q9H825-1", "name": "tRNA N(3)-cytidine methyltransferase METTL8, mitochondrial", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNMIWRNSISCLRLGKVPHRYQSG-------------------------------YHPVAPLGSRILTDPAKVFEHNMWDHMQWSKEEEAAARKKVKENSAVRVLLEEQVKYEREASKYWDTFYKIHKNKFFKDRNWLLREFPEILPVDQKPEEKARESSWDHVKTSATNRFSRMHCPTVPDEKNHYEKSSGSSEGQSKTESDFSNLDSEKHKKGPMETGLFPGSNATFRILEVGCGAGNSVFPILNTLENSPESFLYCCDFASGAVELVKSHSSYRATQCFAFVHDVCDDGLPYP--FPDGILDVILLVFVLSSIHPDRTLFI--------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZFN6-1", "uniprot_id": "D3ZFN6_RAT", "id": "D3ZFN6-1", "name": "tRNA N(3)-cytidine methyltransferase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MINYGILKVLFGMNVIWRNCICRLRQGKVPHRCQSG-------------------------------VHPVAPLGSRILTDPTKVFEHNMWDHMQWSKEEEDEARKKVEENSATRVAPEEQVKFENAANKYWDTFYQTHKNKFFKNRNWLLREFPEILPVDQNTKEKLGESSWDPARSSIS---------RTQGTETHRQETFVSSEPGSR-ERSASNPDLEEYSRGPRKAEQFPGSKATFRILEVGCGAGNSVFPILNTLQNIPGSFLYCCDFAPEAVELVKSHEAYSEAHCSAFIHDVCDDGLAYP--FPDGTLDVILLVFVLSSIHPDRMQAVIHRLSRLLKPGGMLLFRDHGRYDNAQLRFKKGRCLSENFYVRGDGTRAYFFTKGEIHRMFCEAGLHEKQNLVDHRLQVNRKKQIQMHRVWVQGKFQKPSCWTPRSADEHALPSPD-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08641-1", "uniprot_id": "AB140_YEAST", "id": "Q08641-1", "name": "tRNA(Thr) (cytosine(32)-N(3))-methyltransferase", "aln": "MGVADLIKKFESISKEEGDATVDTNSSSKPLKSNDETKELHQQESTAVPQEVDVNEEFENEPETINSSRTAEKPLETNLPKPETNEEDEEEGSMSENKIYSKGENADINVNDFQEYKEMENTGAEVLASSVEESDAIQEGVAEETEGIATPKQKENEKNDESEEESANNASEPAEEYSQSEEDADIEQSNGKETENAENASQQANDGSTSTTTSKNKKKKNKKKNKKKRNGNVNTNANVDDSTKTGENDDTTGDTTSSTTSAIQEVNDLEVVDDSCLGIDQQHNREHLKALTQDVKEETLENIAHEGRGDNTGDQNAVEKSDFEKSDTEGSRIGRDLPFEFGKRNLTEESDVWDHNAWDNVEWGEEQVQQAEEKIKEQFKHPVPEFDKKLYNENPARYWDIFYKNNKENFFKDRKWLQIEFPILY--------------------------------------------------------------------ASTRKDAEPVT-----IFEIGCGAGNTFFPILKDN-ENENLRIIAADFAPRAVELVKNSEQFNPKYGHATVWDLANPDGNLPDGVEPHSVDIAVMIFVFSALAPNQWDQAMDNLHKILKPGGKIIFRDYGAYDLTQVRFKKNRILEENFYVRGDGTRVYFFSEEKLREIFTKKYFLENKIGTDRRLLVNRKRQLKMYRCWVQAVFDVPQ-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q86BS6-1", "uniprot_id": "MET2_DROME", "id": "Q86BS6-1", "name": "tRNA N(3)-methylcytidine methyltransferase Mettl2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLTTSS---------------------------STMLG-----------------------------------KYGWQILRRLASKSWEHTRQ---------------------------------RKKPSGAGSRVLTDAREVFEFNAWDHVQWDEEQELAAKAAVAKNSTSKMEAEQKERFQTDAPKFWDSFYGIHDNRFFKDRHWLFTEFPELAPL------------------------------------------------------------------AADSAVLQPRS-----IFELGCGVGNTILPLLQYS-SEPQLKVFGCDFSARAIEILRSQRQFDEKRCEVFVMDATLDHWQVP--FEENSQDIIVMIFVLSAIEPKKMQRVLDNCYRYLRPGGLLLFRDYGRYDLAQLRFKSGKCMEDNFYVRGDGTMVYFFTEEELRGMMTQAGLQEEQLIVDRRLQVNRCRGLKMYRVWIQTKFRKPL-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * * : *:..* **:::*. *: * : :: : .: :: . .:*: ** :.: ***:*:** *** : * : *:*:***.**:.:*:*: . : .**:. *:::::. : . : * * . *: :::**:*:: *.: ", "identical_positions": 42, "similar_positions": 60, "identity": "5.79%" }, { "cls_id": "homologset.agr.SGD:S000005767", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LTV5-1", "uniprot_id": "A0ABK0LTV5_RAT", "id": "A0ABK0LTV5-1", "name": "tetrahydrofolate synthase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSWARSHLCSALSLAAVSARGATMEGAAYR--------------------------------WLSAWPAPQEPS-----------------MEYQDAVRTLNTLQTNASCLEEVKRQRS--DPQAQLEAMEVYLARSGLQVEDLNQLKIIHVTGTKGKGSTCAFTERILRNYG---LKTGFFSSPHLVQVRERIRINGKPISPELFTKYFWHLYQQLEEFKDDS-------HISMPSYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAFDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIAWQKGGIFKPGVPAFTVL-QPEGPLAVLRDRAQQISCPLYLCPPLEALE--QVGLPLSLGLEGEHQRHNAALALQLARCWLEQQNYHDIQELKASKPSIRWQLPLAPVFRPTPHMRRGLRDTEWPGRTQVLQRGPVTWYLDGAHTTSSVQACVHWYCQSLERSRRTDGGHEVHILLFNSTGDRDSAALLKLLQP-----CHFDYAVFCPNVTEISSIGNAGFLGNAHTHMVRGPRGHVVKMSERALELEHQALPPMTVSSRLHWSRSTVWTTNGVWCRDACRDQELSRCSLSLRPLSSPPLTCLVLDPTDQQNFTVTLDQVLLRCLQH--QKHWNCLAEKQASSNLWGSCGPESARPGSLLLAPHPPQPTSTSSLVFSCISHALQWISQGRDPIFQPESPPRNLLNHPTANSGASILREAAAIHVLVTGSLHLVGGALRLLDPSMSQ------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48760-1", "uniprot_id": "FOLC_MOUSE", "id": "P48760-1", "name": "Folylpolyglutamate synthase, mitochondrial", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSWARSRLCSTLSLAAVSARGATTEGAARR--------------------------------GMSAWPAPQEPG-----------------MEYQDAVRTLNTLQTNASYLEQVKRQRS--DPQAQLEAMEMYLARSGLQVEDLNRLNIIHVTGTKGKGSTCAFTERILRNYG---LKTGFFSSPHMVQVRERIRINGKPISPELFTKHFWCLYNQLEEFKDDS-------HVSMPSYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAFDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIAWQKGGIFKPGVPAFTVV-QPEGPLAVLRDRAQQIGCPLYLCPPLEALE--EVGLPLSLGLEGAHQRSNAALALQLAHCWLERQDHQDIQELKVSRPSIRWQLPLAPVFRPTPHMRRGLRDTVWPGRTQILQRGPLTWYLDGAHTTSSVQACVHWYRQSLERSKRTDGGSEVHILLFNSTGDRDSAALLKLLQP-----CQFDYAVFCPNVTEVSSIGNA-----------------------------------------------------------------------------------------DQQNFTVTLDQVLLRCLQH--QQHWNGLAEKQASSNLWSSCGPDPAGPGSLLLAPHPPQPTRTSSLVFSCISHALLWISQGRDPIFQPQSLPRNLLNHPTANSGASILREAAAIHVLVTGSLHLVGGVLKLLDPSMSQ------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05932-1", "uniprot_id": "FOLC_HUMAN", "id": "Q05932-1", "name": "Folylpolyglutamate synthase, mitochondrial", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRARSHLRAALFLAAASARGITTQVAARR--------------------------------GLSAWPVPQEPS-----------------MEYQDAVRMLNTLQTNAGYLEQVKRQRG--DPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTECILRSYG---LKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGS-------CVSMPPYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIAWQKGGIFKQGVPAFTVL-QPEGPLAVLRDRAQQISCPLYLCPMLEALE--EGGPPLTLGLEGEHQRSNAALALQLAHCWLQRQDRHGAGEPKASRPGLLWQLPLAPVFQPTSHMRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQGRERPSGGPEVRVLLFNATGDRDPAALLKLLQP-----CQFDYAVFCPNLTEVSSTGNA-----------------------------------------------------------------------------------------DQQNFTVTLDQVLLRCLEH--QQHWNHLDEEQASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSPPKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLKLLEPALSQ------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q7N0-1", "uniprot_id": "F1Q7N0_DANRE", "id": "F1Q7N0-1", "name": "Folylpolyglutamate synthase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLLFRVLENLRAWTEVSARNRHWTSIVGLSVR--------------------------------FSSTKAAPRYRR-----------------MDYQDAVCTLNTLQTNASALEQVKRERG--HPQLQLQAMRGFLQRAGLKVEELDRLNIIHVTGTKGKGSTCAFTEKILRNYG---FRTGFYSSPHLVQVRERIRINGQPIGKELFTKYFWQVYGRLEETKDAH-------GGSMPAYFRFLTILAFHVFLQEKVDLAVIEVGIGGAYDCTNIIRRPWVCGISSLGIDHTSILGDTIEKIAWQKGGIFKPGVPAFTVK-QPDGPMKVLQERAEEVGCSLSVCPDLDEYE--SEG-SLSLGLAGQHQRSNASLALQLSHTWLQRHILTDP-----ASPVEFSGVSSAPAFQPSPAMIKGLAETEWPGRNQTLKHGPVTYYMDGAHTTRSMQACVRWFNEVATQHERNAGGSVLRVLLFNATGERDCAAMLKLLAP-----CHFDFAVFCPNITEAIASCNA-----------------------------------------------------------------------------------------DQQNFNVSVENMLTRCLDN--QQSWRVLNGHEEKP------EAELLIGGGLPLVAER----HGDTLVFPCILSALQWISQGRDSVLADAN-KHTIPVKPSINAKAAPLREAQNIHVLITGSLHLVGGALKHLDPALNS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08645-1", "uniprot_id": "FOLE_YEAST", "id": "Q08645-1", "name": "Folylpolyglutamate synthase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHKGKKNYPNLITSFRMNLKKIILNHDRFSHPERWKTNALLRFTFVYI--------------------KFLFDLMIIKNPLRMVG-----------------KTYRDAVTALNSLQSNYANIMAIRQTGDR-KNTMTLLEMHEWSRRIGYSASDFNKLNIVHITGTKGKGSTAAFTSSILGQYKEQLPRIGLYTSPHLKSVRERIRINGEPISEEKFAKYFFEVWDRLDSTTSSLDKFPHMIPGSKPGYFKFLTLLSFHTFIQEDCKSCVYEVGVGGELDSTNIIEKPIVCGVTLLGIDHTFMLGDTIEEIAWNKGGIFKSGAPAFTVEKQPPQGLTILKERAEERKTTLTEVPPFKQLE--NVK----LGIAGEFQKSNASLAVMLASEILHTSN------------ILEEKIKCSSNASIPEKFIIGLQNTKWEGRCQVLEKGKNVWYIDGAHTKDSMVAASTWFRDMVRLSKRK------KILLFNQQ-SRDANALVNNLYSSVSPEITFDDVIFTTNVTWKSGSYSA-----------------------------------------------------------------------------------------DLVSMNTSQEDVEKLKVQESLVKNWNKIDDN------------------------------RAKTHVTASIEEANELIETLYD----------------------------EPADIFVTGSLHLVGGLLVVFDRIDVK------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VYL1-1", "uniprot_id": "Q9VYL1_DROME", "id": "Q9VYL1-1", "name": "Folylpolyglutamate synthase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MAACLLRYLVRQSRKPRSLVVSRESSHCSRMSTYSTVTNLSTVKMQRIQHLAAFRSGVSLAERVLNPPQQSINGNHVSGNIQCSSDNNNKDTN-----------------AAFELAIKQLNSLQSNDAAIRNSMSNSR----VDTKADTIKYLERSGLPLETVEQLSFIHVAGTKGKGSTCALTESLLRHQG---FRTGFFSSPHILFTNERIRIDGQLLSKDKFTEQFWKVYNRLWDLREHD--------HDMPAYFKFLTILGFHVFVAENVDVVVLEVGIGGEHDCTNIVRNVRTVGITSLGLEHTELLGRTLPEIAWQKAGIIKTGSHVFTHVTQPEC-LEVIRQRTKEHSATLYEVPPTEDYFR-SKAYAPIWQTFSNLIRLNGSLAIQLAQDWLSQSG---------------KQQHTPNEVKMDPQLLDGLISTHWPGRCQLIEWHGMRLHLDGAHTLESMEVCTDWFEKNVRDSVNP------KILIFNRTGESGFAPLLKLLNR----TCDFDMVCFVPNLATSTPNAPS--------------------------------------------------------------------------------------------QVMVRFSPEMQLNRARIIASAWSDLCATEQK---------------------------KDVGQVYNTLTDAFTAIRQRFPQATDNEG----------------------QLEVLVTGSIHLLGAAISALDLIDDPKSRTDK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQW0-1", "uniprot_id": "Q9VQW0_DROME", "id": "Q9VQW0-1", "name": "", "aln": "MHSVLPLMYRRRSSHLKALQWTIQSSQNFFKMSFKAPSIKVPKAAAIKELANKPTQPQSQPSQSQSSATQPTQPPQQAEIKKNPLTMGAISPAPPTPISPKPSVQPKIPDQRAKWMAKVSPESQRKAKLAAAGGSPPSGPPKNQFSQANNPSFAMPGQSSPANFSAAPKTQASWQQKVEKSAENEDSGAFKGASSESQRKNWMNRMQGSQQRKQNQWLKEMQAKQQAGKDIQAQKMQKMESQKATTTPAAPPKEAAPSTPQPAEKPEEKSPEHLAYLDAIKQLNSYQVLEPTSGRATTKSSRKEQDPVIEQTLECLEKSGLTKKDLKAIPVIQVAGSKGRGSTCAIVESILRCHG---VKTGVLSSPHLFLTSERIRIDGEPLSDVQFTELFWKINTDLANMQPTP------------SYNKIMTVMAFHAFHQAGVEVAILEVGNAGASDATNIASHAQTIGITTLGWEQSSNLGNSLRDIAWAKASIMKPEANIYTNVTQTEC-CEVLAQKAKQIGAQLRRVPTFNDYVEGDMNNKLLMNKANYSMRLNGSLAVQLAYDFLKRHKP------------EYVVGLEHNSTLLTPGASRGIEIFEQPGHFDFMRHDMFNVYLDSADTFESMMACRDWFYTRTRANRQP------KILLFNKVNEFNAKDLLTIIRSN----LRFEEACFVPNPNYFEGEILAE-----------------------------------------------------------------------------------------EDGKAMVWHGMEELQRAKRNAGNWRALCEENGK---------------------------RDNSQLSISINAFFEYLTNKYGKQKYGMK---------------------NELDVLVTGSRQLVAATISCLRKMKSSNPWQ--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *: **: * : * . .. : .::::*:**:***.*:.. :* : *. :***: . *****:*: :. *:: *: : * . * :::*::.**.* . : *** .* *.*** . . *:: ** ::: ** :: .*** *..*:* :* *. :: ::::: * * . . . : *.:**: *: * *: *: : :. ::*.*.* * .. *: . ::*:** . . ::. : *: . * .* : . * : : : : .:::*** :*:.. : : ", "identical_positions": 77, "similar_positions": 117, "identity": "8.24%" }, { "cls_id": "homologset.agr.SGD:S000005769", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADZ9-1", "uniprot_id": "D4ADZ9_RAT", "id": "D4ADZ9-1", "name": "Pseudouridylate synthase 7 homolog", "aln": "---MEMTSVSLKRGCLVVEDNDSVTPHEETKKQKVSEGCVTNSPDGVESDSLHSSETKPGPPEAESTLKDGENSGAQVQEEEEEEEEEDGLSEAGEEEEPESFADMMKHGLTELDVGITKFVSPHQGFSGILKERYSDFVVHEIGKDGRISHLDDLSVPVDEEDPPEDALTVLTAEDRQQLEELQLFKNKETSVAIEVIEDTKEKRTIIHQAIKSLFPGLETKTEEREGKRYIVAYHAAGKKALANPRKHSWPKSRGSYCHFVLYKENKDTMDAINVLSKYLRVKPNIFSYMGTKDKRAITVQEIAVLKISAQRLAHLNKCLMNFKLGNFSYQKTPLKLGELQGNHFTVVLRNITG------TDEQVQQAMHSLQQTGFINYYGMQRFG-TTAVPTYQVGRAILQNSWTEVMDLILKPRSGAEKGYLVKCREEWAKTKDPASALKKLPVKRCVEGQLLRGLSK--------YGLKNIVSAFGIIPRNNRLMYIHSYQSYVWNSMVSRRIELYGLKPVPGDLVLKGATAT----YIEEDDINN------------------------------------------------YSIHDVVMPLPGFDVIYPKHK-ISEAYREMLAADNLDIDNMRHTIRDYSLSGAYRKIIIRPQSVSWEVVAYDDPKIPLFNTDVDNLEGK--------------PPPVFASEGRYRALKMDFSLPPSTYATMAIREVLKMDTSIKNQTQLNTSWLR------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VU7-1", "uniprot_id": "PUS7_MOUSE", "id": "Q91VU7-1", "name": "Pseudouridylate synthase 7 homolog", "aln": "---MEMTSTSLKRGCLVVEDNDSVTPHDETKKQKVSEGCLTSSQDGVENDGLHRSENEPGPPEAESTVKDDENSSAQVQEEEEEEEEEDGLSEAGEEEEAESFADMMKHGLTELDVGICKFVSSHHGFSGILKERYSDFVVHEIGKDGRISHLDDLSVPVDEEDPPEDALTVLTAEDRQQLEELQLFKNKETSVAIEVIEDTKEKRTVIHQAIKSLFPGLETKTEDREGRKYIVAYHAAGKKALANPRKHSWPKSRGSYCHFVLYKENKDTMDAINVLSKYLRVKPNIFSYMGTKDKRAITVQEIAVLKISAQRLAHLNKCLMNLKLGNFSYQKTPLKLGALQGNHFTVVLRNITG------TDEQVQQAMQSLRETGFINYYGMQRFG-TTAVPTYQVGRAILQNSWTEVMDLILKPRSGAEKGYLVKCREEWAKTKDPASALKKLPVKRCVEGQLLRGLSR--------YGMKNIVSAFGIIPRNNRLMYIHSYQSYVWNTMVSRRIEEYGLRPVPGDLVLKGATPT----YIEEDDVDN------------------------------------------------YSIHDVVMPLPGFDVIYPKHK-ISEAYREMLAADNLDIDNMRHTIRDYSLSGAYRRIIIRPQSVSWEVVAYDDPKIPLFNTDVDNLEGK--------------PPPVFASEGKYRALKMDFSLPPSTYATMAIREVLKMDTSIKNQTQLNTSWLR------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PZ0-1", "uniprot_id": "PUS7_HUMAN", "id": "Q96PZ0-1", "name": "Pseudouridylate synthase 7 homolog", "aln": "MEMTEMTGVSLKRGALVVEDNDSGVPVEETKKQKLSECSLTKGQDGLQNDFLSISEDVPRPPDTVSTGKGGKNSEAQLEDEEEEE--EDGLSEECEEEESESFADMMKHGLTEADVGITKFVSSHQGFSGILKERYSDFVVHEIGKDGRISHLNDLSIPVDEEDPSEDIFTVLTAEEKQRLEELQLFKNKETSVAIEVIEDTKEKRTIIHQAIKSLFPGLETKTEDREGKKYIVAYHAAGKKALANPRKHSWPKSRGSYCHFVLYKENKDTMDAINVLSKYLRVKPNIFSYMGTKDKRAITVQEIAVLKITAQRLAHLNKCLMNFKLGNFSYQKNPLKLGELQGNHFTVVLRNITG------TDDQVQQAMNSLKEIGFINYYGMQRFG-TTAVPTYQVGRAILQNSWTEVMDLILKPRSGAEKGYLVKCREEWAKTKDPTAALRKLPVKRCVEGQLLRGLSK--------YGMKNIVSAFGIIPRNNRLMYIHSYQSYVWNNMVSKRIEDYGLKPVPGDLVLKGATAT----YIEEDDVNN------------------------------------------------YSIHDVVMPLPGFDVIYPKHK-IQEAYREMLTADNLDIDNMRHKIRDYSLSGAYRKIIIRPQNVSWEVVAYDDPKIPLFNTDVDNLEGK--------------TPPVFASEGKYRALKMDFSLPPSTYATMAIREVLKMDTSIKNQTQLNTTWLR------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSK9-1", "uniprot_id": "PUS7_DROME", "id": "Q9VSK9-1", "name": "Pseudouridylate synthase 7 homolog", "aln": "----------MGKDRGRGRRNNHSGPYNKSNWRGQKKDRPQNNGGGQRNS----------APQQKSTLLETQVGITEFTNPEAPGFTGILKSRFSDFHVNEIDSNGKVLELNDLSVPKVAIVAVAENELDNWRKELEAVIGPEVWQD--IANLAKAKNDPAIEQKVEIDVTTLDKEQRTQVHQMIKQLYKGKLLSTTIGQQQAKPKVQEEASLENKDAAEGETSTQKDSQVPAEEKKTIKVFKPKPGRGDKRWSFPADYVTFLVHKTNLVTSDVASTLAARLNLRPSQVNYSGIKDKRAKTTQKFSVKRRTPESILVAARSQRNVHIGNFGFESNTLKLGDLQGNRFRIALRHIAKE-----KREEIEQALQSLKERGFINYYGLQRFGNSASVPTYEVGVALLKHDYKLACELILKPRD-SDVEFLRPIREEWWKNRDSAAAAAQIYGEKFIEKKLLDGLAR--------FGESDYSSALRQIPRNMLMLYPHAYQSLIFNRIASRRIKEFGLKLIPGDLVYVEQDQS----EASEEQAQQGEALEEQKEEEPNDEPLEVPEGDEAIEEESIFKRKVRPLTAEDIASGKYKLCDVVLPLPGHDITYPSNE-CGAWYEEMLAEVGLSSDQLKHKEKTYALAGAYRKMIISSSDLKWSFRMYNTPEDTLIASDWELLKNIPV------------APEPAEAEANYMALLLEFSLPTAAYATMFLRELLKQDTSSASQTQLEKQAMAKEDNEKKAVGTQEEQMEVVKEVADEDGQETEQAETQGAEEAV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08647-1", "uniprot_id": "PUS7_YEAST", "id": "Q08647-1", "name": "Multisubstrate pseudouridine synthase 7", "aln": "-------MSDSSEATVKRPLDAHVGPSENAAKKLKIEQRTQADG-----------------------IHEADVGITLFLSPELPGFRGQIKQRYTDFLVNEIDQEGKVIHLTDKGFKMPKKPQRSK-EEVNAEKESEAARRQEFNVDPELRNQLVEIFGEEDVLKIESVYRTANKMETAKNFEDKSVRTKIHQLLREAFKNELESVTTDTNTFKIARSNRNSRTNKQEKINQTRDANGVENWGYGPSK---------DFIHFTLHKENKDTMEAVNVITKLLRVPSRVIRYAGTKDRRAVTCQRVSISKIGLDRLNALNRTLKGMIIGNYNFSDASLNLGDLKGNEFVVVIRDVTTGNSEVSLEEIVSNGCKSLSENGFINYFGMQRFG-TFSISTHTIGRELLLSNWKKAAELILSDQD-NVLPKSKEARKIWAETKDAALALKQMPRQCLAENALLYSLSNQRKEEDGTYSENAYYTAIMKIPRNLRTMYVHAYQSYVWNSIASKRIELHGLKLVVGDLVIDTSEKSPLISGIDDEDFDEDVREAQFIR--------------------------AKAVTQEDIDSVKYTMEDVVLPSPGFDVLYPSNEELKQLYVDILKADNMDPFNMRRKVRDFSLAGSYRTVIQKPKSLEYRIIHYDDPSQQLVNTDLDILNNTRAKESGQKYMKAKLDRYMPDKGGEKTAVVLKFQLGTSAYATMALRELMKLETSRRGDMCDVKENI-------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * ::: : : . . . : . . * .. : * : *.: .. . .:. . *. * : : * . : : : * : :: : . ::: . : .:: : : .: * ::* * * :. ..:: *.: . . * * **:** * *..:: : : : : .. :**:.:.. .*:** *:**.* :.:*.:: : :.:. :** : *****:*:**** : ::.*: :* :* .:. . :***. :. *: * :.:*.: * :: : * ** .*:. :. . :*: **** :* *:*** ::* :.*:**: .**: : **** : .::: :: *.: ***:* **.*: **.:: * ::* .:. ::::. : ::*:*:** :* ...:.: . *: *. *. :* : *:. .. *: :.*.* .::**** :**::* :** .: . : ", "identical_positions": 111, "similar_positions": 203, "identity": "14.1%" }, { "cls_id": "homologset.agr.SGD:S000005770", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CHK4-1", "uniprot_id": "KAT5_MOUSE", "id": "Q8CHK4-1", "name": "Histone acetyltransferase KAT5", "aln": "---------------MAEVG-EIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLDL-KKIQFPKKE-AKTPTKNGLPG-----------SRPGSPEREVP---------ASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSP-ATPVPSETAPASVFPQNGSARRAVAAQPGRKRKSNCLGTD---------------------EDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLT-----------------KCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLK-SESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHER---AMLKRLLRIDSKCLHFTPKDWSK---RGKW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99MK2-1", "uniprot_id": "KAT5_RAT", "id": "Q99MK2-1", "name": "Histone acetyltransferase KAT5", "aln": "---------------MAEVG-EIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLDL-KKIQFPKKE-AKTPTKNGLPG-----------SRPGSPEREVP---------ASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSP-ATPVPSETAPASVFPQNGSARRAVAAQPGRKRKSNCLGTD---------------------EDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLT-----------------KCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLK-SESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHER---AMLKRLLRIDSKCLHFTPKDWSK---RGKW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92993-1", "uniprot_id": "KAT5_HUMAN", "id": "Q92993-1", "name": "Histone acetyltransferase KAT5", "aln": "---------------MAEVG-EIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLDL-KKIQFPKKE-AKTPTKNGLPG-----------SRPGSPEREVP---------ASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSP-ATPVPSETAPASVFPQNGAARRAVAAQPGRKRKSNCLGTD---------------------EDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLT-----------------KCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLK-SESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHER---AMLKRLLRIDSKCLHFTPKDWSK---RGKW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QDW0-1", "uniprot_id": "A0A8M9QDW0_DANRE", "id": "A0A8M9QDW0-1", "name": "Histone acetyltransferase KAT5", "aln": "---------------MAEPTVEIVEGCRLPVLRKNQENEDEWPLAEILSVKDIPGRKLYYVHYIDFNKRLDEWVTPDRLDL-KKLQFPKKE-AKTPTKNGLPG-----------SRPSSPEREVRKSLDLNVQSASAPSRGKTLPTPKRKAESVSLATQ---VTAATPVPSLPSS--AEASQASVYPAMRDSSF-SIKAREEHEQLTSLTTNGTTRRLIPSQPGRKRK-NCVGTEEIVKVFQNNSPRSSTVYLPPGEDSQDSSDGIPSAPRMTGSLVSDRSHDDIITRMKNIDCIELGRHRLKPWYFSPYPQELTTLPILYLCEFCLKYLKSLKCLQRHLVRAVLGPDVTHSQHQIKTKCNLRHPPGNEIYRKGTISFFEIDGRKNKMYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDSKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMNLK-SENGERPQMTINEISEITSVKKEDVISTLQYLNLINYYKGQYILTLSEDIVEGHER---AMHKRHLRIDSKCLHFTPKDWSK---RGKW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q960X4-1", "uniprot_id": "TIP60_DROME", "id": "Q960X4-1", "name": "Histone acetyltransferase Tip60", "aln": "MKINHKYEFDDDVASICESTAALTEGCRLPVR---MHKTDDWPLAEIVSIKELDGRRQFYVHYVDFNKRLDEWVNEEDLYT-RKVQFPRRDGSQTGTSTGVTTPQRHHSLAGSVSRPTSPQHPGSG----ALAAIPQTPTGASGSVPPPAGIPNSVAPPGTPSSGGELVNGNNLAAALQKRINRKRKNHGGSAHGHHSLTSQQQQSHPHPTTPQTPTATPVHVTGDGLISGAAND----------------------DGDGSQDGKTPTPRQSGSMVT--HQDDVVTRMKNVEMIELGRHRIKPWYFSPYPQELCQMPCIYICEFCLKYRKSRKCLERHLS-----------------KCNLRHPPGNEIYRKHTISFFEIDGRKNKVYAQNLCLLAKLFLDHKTLYYDTDPFLFYVMTEFDSRGFHIVGYFSKEKESTEDYNVACILTMPPYQRKGYGKLLIEFSYELSKFEGKTGSPEKPLSDLGLLSYRSYWAQTILEIFISQNPSTDGEKPTITINDICECTSIKKEDVISTLQNLNLINYYKGQYIVCINRVIIEQHRR---AMDKRKIRIDSKCLHWTPKDWSK---RSK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08649-1", "uniprot_id": "ESA1_YEAST", "id": "Q08649-1", "name": "Histone acetyltransferase ESA1", "aln": "--MSHDGKEEPGIAKKINSVDDIIIKCQCWVQ-----KNDEERLAEILSINTRKAPPKFYVHYVNYNKRLDEWITTDRINLDKEVLYPKLK--------------------------------------------------------------------------------------ATDEDNKKQKKKKATNTSETPQDSLQDGVDGFSRENTDVMDLDN-------LNVQGIK----------------------DENISHEDEIKKLRTSGSMTQN---PHEVARVRNLNRIIMGKYEIEPWYFSPYPIELTDEDFIYIDDFTLQYFGSKKQYERYRK-----------------KCTLRHPPGNEIYRDDYVSFFEIDGRKQRTWCRNLCLLSKLFLDHKTLYYDVDPFLFYCMTRRDELGHHLVGYFSKEKESADGYNVACILTLPQYQRMGYGKLLIEFSYELSKKENKVGSPEKPLSDLGLLSYRAYWSDTLITLLVEHQ-------KEITIDEISSMTSMTTTDILHTAKTLNILRYYKGQHIIFLNEDILDRYNR---LKAKKRRTIDPNRLIWKPPVFTASQLRFAW", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VAV6-1", "uniprot_id": "Q9VAV6_DROME", "id": "Q9VAV6-1", "name": "Histone acetyltransferase", "aln": "-------------------------------------MDKENRSGDHLKYQPLGDQDGISSKLPDIPRALQLTNAKESSATRGLGQSASKS----------------------------------------------------------------------------------------EMGKSQLQNDSSLQKNIQETKTITGSCIEAQRIGATPKKQLEGVKEPNMISLLHTN---------------------ASSNVDDRQRQETIDNEKSDVQKEKEDAKVKVIRNIEKVQFGRYEIETTSSSPYPVINDKATTIYVCEFCLKYMCLRKSYSYHLY-----------------DCKKRCPPGSLLYRKDNIYIYEVDGHKEQLYCQCLCLMSKLFLENKKILYSSSSFLFYILCLKDKDGEHFAGYFAREKTMLN-INLNCILVLPPYMRKGYGKLLIDLSYEISRREACIGGPKKPLSKVARLCYLSYWGHILLNLLRHHS-----SPDLVTIEELSKATGFREEDIISTLEFMGMTKYYKVDHIMFYTTSSIIEDRRGLAQFKKPRLTIHRNRLSWKTPTGRK-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .: :. : : : : *: : . . . . . : . * . : ::*:: : :*::.::. **** :*: :* *:* * . : .* * ***. :**. : ::*:**:*:: :.: ***::* **::*.: *. ..**** : * * *:.***::** : *: ***.:* * * *******::***:*: * * *:****.:. *.* :**.. :: :: . :**:::.. *.. *:: * : :.: .*** ::*: . : .* * *. : * :.. ", "identical_positions": 86, "similar_positions": 114, "identity": "14.41%" }, { "cls_id": "homologset.agr.SGD:S000005771", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A598-1", "uniprot_id": "D4A598_RAT", "id": "D4A598-1", "name": "Acyltransferase", "aln": "-------------------------------------------------------MFWPTKKDLKTAMEVFALFQWALSALVIVITVIMVNLYLVVFTSFWPVTVLMLLWLAFDWK--TPERGGRRFNCVRRWCLWKHYSNYFPLKIVKTKDIPTNH------------------------------------------NYILACHPHGLLSHSWFGHFSTDTTGFSKIFPGITPYMLTLGAFFWVPFLREYIMSTGACSVSQSSIDFLLTQKG-----------TGNMLVVVVGGLAECKYSMPGSTTLFLKKRQGFVRTALRYG-VSLIPAYAFGEADLYDQHIFTPGSFISHFQKWFQ----KMVHVYPCAFYGRG-FTKNSWGLLPYSQPVTTIVGEPLPLPK-IENPSQEIVAKYHTLYIDALRKLFDQHKTKFGISETQELVII-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6E1M8-1", "uniprot_id": "AWAT2_MOUSE", "id": "Q6E1M8-1", "name": "Acyl-CoA wax alcohol acyltransferase 2", "aln": "-------------------------------------------------------MFWPTKKDLKTAMEVFALFQWALSALVIVTTVIIVNLYLVVFTSYWPVTVLMLTWLAFDWK--TPERGGRRFTCVRKWRLWKHYSDYFPLKMVKTKDISPDR------------------------------------------NYILVCHPHGLMAHSCFGHFATDTTGFSKTFPGITPYMLTLGAFFWVPFLRDYVMSTGSCSVSRSSMDFLLTQKG-----------TGNMLVVVVGGLAECRYSTPGSTTLFLKKRQGFVRTALKHG-VSLIPAYAFGETDLYDQHIFTPGGFVNRFQKWFQ----KMVHIYPCAFYGRG-LTKNSWGLLPYSQPVTTVVGEPLPLPK-IENPSEEIVAKYHTLYIDALRKLFDQHKTKFGISETQELVIV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6E213-1", "uniprot_id": "AWAT2_HUMAN", "id": "Q6E213-1", "name": "Acyl-CoA wax alcohol acyltransferase 2", "aln": "-------------------------------------------------------MLLPSKKDLKTALDVFAVFQWSFSALLITTTVIAVNLYLVVFTPYWPVTVLILTWLAFDWK--TPQRGGRRFTCVRHWRLWKHYSDYFPLKLLKTHDICPSR------------------------------------------NYILVCHPHGLFAHGWFGHFATEASGFSKIFPGITPYILTLGAFFWMPFLREYVMSTGACSVSRSSIDFLLTHKG-----------TGNMVIVVIGGLAECRYSLPGSSTLVLKNRSGFVRMALQHG-VPLIPAYAFGETDLYDQHIFTPGGFVNRFQKWFQ----SMVHIYPCAFYGRG-FTKNSWGLLPYSRPVTTIVGEPLPMPK-IENPSQEIVAKYHTLYIDALRKLFDQHKTKFGISETQELEII-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2ADU9-1", "uniprot_id": "AWAT1_MOUSE", "id": "A2ADU9-1", "name": "Acyl-CoA wax alcohol acyltransferase 1", "aln": "-------------------------------------------------------MSCSMKT---EHLQSLSLLQWPLSYVAMFWIVQPL-LICLLFTPLWPLPTVYFVWLLLDWK--TPDKGGRRSDWVRNWNVWNHIRDYFPITILKTKDLSPSE------------------------------------------NYIMGVHPHGLLTFGAFCNFCTEATGFSKTFPGITPHLATLSWFFKIPIIRDYIMAKGLCSVSQASIDYLLSH-G-----------TGNLVGIVVGGVGEALQSVPNTTTLLLKKRKGFVRTALQHG-AHLVPTFTFGETEVYDQVLFHEDSRMFKFQSLFR----RIFGFYCCVFYGQG-FHQDCKGLLPYHKPIITVVGEALPLPQ-VKNPSPEIVDKYHALYMDALYKLFEQHKVQYGCSNTQKLIFL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZVA9-1", "uniprot_id": "D3ZVA9_RAT", "id": "D3ZVA9-1", "name": "Acyltransferase", "aln": "-------------------------------------------------------MSCSMKL---EYLQSLSLLQWPLSYLAIFWIVQPL-FFSLFFTPLWLLPSLYVVWFILDWK--TPNQGGRRSAWVRNWNIWTHIRDYFPITILKTKDLSPSQ------------------------------------------NYIMGVHPHGLLTFGAFCNFCTEATGFSKTFPGITPHLATLSWFFKIPLIRDYIMAKGVCSVSQASIDYLLSH-G-----------TGNLVGIVVGGVGEALQSVPNTTTLILKKRKGFVRTALRHG-AHLVPTFTFGETEVYDQVVFHEESRMFKFQSFFR----RIFGFYFCVFYGQG-FHQECKGLLPYHRPIVTVVGEPLPLPQ-VKNPSPEIVDKYHALYMDALYKLFEQHKVQYGCSDTQKLMFL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q58HT5-1", "uniprot_id": "AWAT1_HUMAN", "id": "Q58HT5-1", "name": "Acyl-CoA wax alcohol acyltransferase 1", "aln": "-------------------------------------------------------MAHSKQP---SHFQSLMLLQWPLSYLAIFWILQPL-FVYLLFTSLWPLPVLYFAWLFLDWK--TPERGGRRSAWVRNWCVWTHIRDYFPITILKTKDLSPEH------------------------------------------NYLMGVHPHGLLTFGAFCNFCTEATGFSKTFPGITPHLATLSWFFKIPFVREYLMAKGVCSVSQPAINYLLSH-G-----------TGNLVGIVVGGVGEALQSVPNTTTLILQKRKGFVRTALQHG-AHLVPTFTFGETEVYDQVLFHKDSRMYKFQSCFR----RIFGFYCCVFYGQS-FCQGSTGLLPYSRPIVTVVGEPLPLPQ-IEKPSQEMVDKYHALYMDALHKLFDQHKTHYGCSETQKLFFL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2ADU8-1", "uniprot_id": "DG2L6_MOUSE", "id": "A2ADU8-1", "name": "Diacylglycerol O-acyltransferase 2-like protein 6", "aln": "-------------------------------------------------------MAAFSCLDLQEGLRTLSILQWIPVYVLLGTLSILGMPYLLLFTTLWPLSVLFLVWIAYDWN--THIQDGRRSAWVRNWTLWKYFQSYFPVKLVKTHDLSPKH------------------------------------------NYIILSHPHGILSYGAFINFATESTGFSRVFPSITPFLATLEGIFWIPFVRDYLMSLGICPVSKLSLTHKLTQKD-----------SGNAVIIVPGGASESLLSRPGVSMIYLKKRQGFVKLALKTG-AYLVPSYSFGENETYNQETFAEGTWLRFFQKNIQKIGKRILGINLCTIHGRG-LTRGSWGFLPFNHPITTVVGEPLPVPK-IPDPDKETVEKYLELYISALRKLFDQHKAEYGLSKTHELKIL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZTG7-1", "uniprot_id": "D3ZTG7_RAT", "id": "D3ZTG7-1", "name": "Acyltransferase", "aln": "-------------------------------------------------------MAFFSRLDLHEGLRTLSVLQWIPVYVILGTLSILGIPYFLLFSTFWPLSVLFLAWVAYDWN--THSQDGRRSAWVRNWTLWKYFQSYFPVKLVKTHDLSPKH------------------------------------------NYIILSHPHGILCYGAFINFATEATGFSRVFPSITPFLATLEGIFWIPFVRDYVMSMGICPVSELALKHQLTQRG-----------SGNAVIIVPGGASEALLCCPGVSTVYLKKRKGFVKLALKTG-AYLVPSYSFGENEAYNQETFPEGTWLRFFQKNFQKIGKRILGINFCTFHGRG-LTRGSWGFLPFNHPITTVVGEPLPVPK-ILDPDKETVAKYFELYISALRKLFDQHKTKYDFSKTQELTII-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZPD8-1", "uniprot_id": "DG2L6_HUMAN", "id": "Q6ZPD8-1", "name": "Diacylglycerol O-acyltransferase 2-like protein 6", "aln": "-------------------------------------------------------MAFFSRLNLQEGLQTFFVLQWIPVYIFLGAIPILLIPYFLLFSKFWPLAVLSLAWLTYDWN--THSQGGRRSAWVRNWTLWKYFRNYFPVKLVKTHDLSPKH------------------------------------------NYIIANHPHGILSFGVFINFATEATGIARIFPSITPFVGTLERIFWIPIVREYVMSMGVCPVSSSALKYLLTQKG-----------SGNAVVIVVGGAAEALLCRPGASTLFLKQRKGFVKMALQTG-AYLVPSYSFGENEVFNQETFPEGTWLRLFQKTFQDTFKKILGLNFCTFHGRG-FTRGSWGFLPFNRPITTVVGEPLPIPR-IKRPNQKTVDKYHALYISALRKLFDQHKVEYGLPETQELTIT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DCV3-1", "uniprot_id": "DGAT2_MOUSE", "id": "Q9DCV3-1", "name": "Diacylglycerol O-acyltransferase 2", "aln": "MKTLIAAYSGVLRGERRAEAARSENKNKGSALSREGSGRWGTGSSILSALQDIFSVTWLNRSKVEKQLQVISVLQWVLSFLVLG-VACSVILMYTFCTDCWLIAVLYFTWLAFDWN--TPKKGGRRSQWVRNWAVWRYFRDYFPIQLVKTHNLLTTR------------------------------------------NYIFGYHPHGIMGLGAFCNFSTEATEVSKKFPGIRPYLATLAGNFRMPVLREYLMSGGICPVNRDTIDYLLSKNG-----------SGNAIIIVVGGAAESLSSMPGKNAVTLKNRKGFVKLALRHG-ADLVPTYSFGENEVYKQVIFEEGSWGRWVQKKFQ----KYIGFAPCIFHGRGLFSSDTWGLVPYSKPITTVVGEPITVPK-LEHPTQKDIDLYHAMYMEALVKLFDNHKTKFGLPETEVLEVN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5FVP8-1", "uniprot_id": "DGAT2_RAT", "id": "Q5FVP8-1", "name": "Diacylglycerol O-acyltransferase 2", "aln": "MKTLIAAYSGVLRGERRAEAARSENKNKGSALSREGSGRWGTGSSILSALQDIFSVTWLNRSKVEKHLQVISVLQWVLSFLVLG-VACSVILMYTFCTDCWLIAALYFTWLAFDWN--TPKKGGRRSQWVRNWAVWRYFRDYFPIQLVKTHNLLTTR------------------------------------------NYIFGYHPHGIMGLGAFCNFSTEATEVSKKFPGIRPYLATLAGNFRMPVLREYLMSGGICPVNRDTIDYLLSKNG-----------SGNAIVIVVGGAAESLSSMPGKNAVTLRNRKGFVKLALRHG-ADLVPTYSFGENEVYKQVIFEEGSWGRWVQKKFQ----KYIGFAPCIFHGRGLFSSDTWGLVPYSKPITTVVGEPITVPK-LEHPTQKDIDLYHTMYMEALVKLFDNHKTKFGLPETEVLEVN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96PD7-1", "uniprot_id": "DGAT2_HUMAN", "id": "Q96PD7-1", "name": "Diacylglycerol O-acyltransferase 2", "aln": "MKTLIAAYSGVLRGERQAEADRSQRSHGGPALSREGSGRWGTGSSILSALQDLFSVTWLNRSKVEKQLQVISVLQWVLSFLVLG-VACSAILMYIFCTDCWLIAVLYFTWLVFDWN--TPKKGGRRSQWVRNWAVWRYFRDYFPIQLVKTHNLLTTR------------------------------------------NYIFGYHPHGIMGLGAFCNFSTEATEVSKKFPGIRPYLATLAGNFRMPVLREYLMSGGICPVSRDTIDYLLSKNG-----------SGNAIIIVVGGAAESLSSMPGKNAVTLRNRKGFVKLALRHG-ADLVPIYSFGENEVYKQVIFEEGSWGRWVQKKFQ----KYIGFAPCIFHGRGLFSSDTWGLVPYSKPITTVVGEPITIPK-LEHPTQQDIDLYHTMYMEALVKLFDKHKTKFGLPETEVLEVN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4V9F0-1", "uniprot_id": "DGAT2_DANRE", "id": "Q4V9F0-1", "name": "Diacylglycerol O-acyltransferase 2", "aln": "MKTILAAYSGVKKG---------------------------SGSSILSALHDLPTVPWLTRSKMVKHLQVISVLQFIMTFLTMG-IACSLLLMYMFCTDFWVISVLYVAWLIYDWN--TPGQGGRRSTWVRDWTVWKYMRDYFPIRLIKTHNLLPSR------------------------------------------NYIFGYHPHGILCFGAFCNFGTEATGFTKVFPGIKPSLATLAGNFRLPMFREYLMCGGICPVNRNSIDYLLSSNG-----------TGNAVVIVIGGAAESLDCAPGRNSVMLKKRKGFVKLALKQG-ADLVPVYSFGENEVYKQLIFEEGSWWRTIQRKLQ----KFLGFAPCLFHGCGLFFPESWGLVPYCKPITTVVGEPITVPK-IEEPTQDVIDMYHAMYIRSLKSLFDNYKTRFGLNESDTLIIH-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86VF5-1", "uniprot_id": "MOGT3_HUMAN", "id": "Q86VF5-1", "name": "2-acylglycerol O-acyltransferase 3", "aln": "-----------------------------------------------MGVATTLQPPTTSKTLQKQHLEAVGAYQYVLTFLFMG-PFFSLLVFVLLFTSLWPFSVFYLVWLYVDWD--TPNQGGRRSEWIRNRAIWRQLRDYYPVKLVKTAELPPDR------------------------------------------NYVLGAHPHGIMCTGFLCNFSTESNGFSQLFPGLRPWLAVLAGLFYLPVYRDYIMSFGLCPVSRQSLDFILSQPQ-----------LGQAVVIMVGGAHEALYSVPGEHCLTLQKRKGFVRLALRHG-ASLVPVYSFGENDIFRLKAFATGSWQHWCQLTFK----KLMGFSPCIFWGRGLFSATSWGLLPFAVPITTVVGRPIPVPQ-RLHPTEEEVNHYHALYMTALEQLFEEHKESCGVPASTCLTFI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80W94-1", "uniprot_id": "MOGT2_MOUSE", "id": "Q80W94-1", "name": "2-acylglycerol O-acyltransferase 2", "aln": "-----------------------------------------------------MVEFAPLLVPWERRLQTFAVLQWVFSFLALAQLCIVIFVGLLFTR-FWLFSVLYATWWYLDWD--KPRQGGRPIQFFRRLAIWKYMKDYFPVSLVKTAELDPSR------------------------------------------NYIAGFHPHGVLAAGAFLNLCTESTGFTSLFPGIRSYLMMLTVWFRAPFFRDYIMSGGLVSSEKVSADHILSRKG-----------GGNLLAIIVGGAQEALDARPGAYRLLLKNRKGFIRLALMHG-AALVPIFSFGENNLFNQVENTPGTWLRWIQNRLQ----KIMGISLPLFHGRGVFQYSFG-LMPFRQPITTIVGKPIEVQM-TPQPSREEVDRLHQRYIKELCKLFEEHKLKFNVPEDQHLEFC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2RZ21-1", "uniprot_id": "B2RZ21_RAT", "id": "B2RZ21-1", "name": "Acyltransferase", "aln": "-----------------------------------------------------MVEFAPLLVPWERRLQTFAVLQWVFSFLALAQLCIFIFIGLLFTR-FWLFSVLYATWWYLDWD--RPRQGGRPIQFFRRMAIWKYMKDFFPVSLVKTAELDPSR------------------------------------------NYIAGFHPHGVLAAGAFLNLCTESTGFTSLFPGIRSYLMMLTVWFRAPIFRDYIMSGGLVSSEKVSADHILSRKG-----------GGNLLAIIVGGAQEALDARPGAYRLLLKNRKGFIRLALTHG-AALVPIFSFGENNLFNQVENTPGTWLRWIQNWLQ----KIMGISLPLFHGRGVFQYSFG-LVPFRQPITTVVGKPIEVQM-IPHPSEEEVNRLHQLYIKELCKLFEEHKLKFNVPEDQHLEFC-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3SYC2-1", "uniprot_id": "MOGT2_HUMAN", "id": "Q3SYC2-1", "name": "2-acylglycerol O-acyltransferase 2", "aln": "-----------------------------------------------------MVEFAPLFMPWERRLQTLAVLQFVFSFLALAEICTVGFIALLFTR-FWLLTVLYAAWWYLDRD--KPRQGGRHIQAIRCWTIWKYMKDYFPISLVKTAELDPSR------------------------------------------NYIAGFHPHGVLAVGAFANLCTESTGFSSIFPGIRPHLMMLTLWFRAPFFRDYIMSAGLVTSEKESAAHILNRKG-----------GGNLLGIIVGGAQEALDARPGSFTLLLRNRKGFVRLALTHG-APLVPIFSFGENDLFDQIPNSSGSWLRYIQNRLQ----KIMGISLPLFHGRGVFQYSFG-LIPYRRPITTVVGKPIEVQK-TLHPSEEEVNQLHQRYIKELCNLFEAHKLKFNIPADQHLEFC-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1LT39-1", "uniprot_id": "F1LT39_RAT", "id": "F1LT39-1", "name": "Acyltransferase", "aln": "--------------------------------------------------------MEVPSSPLHRSLQVFAVLQWVFSFLGLALLCLVTLILASLGR-AWTLVVLYLLWLYQDRH--TPRMGGRRSAWVRNWAVWRYFRDYFPIKLVKTAELDPSQ------------------------------------------NYLFGFHPHGVLVVGAFSNFCTEATGFSHLFPGLKPHLLMLPCWFQVPLFRDYIMTSGLVSSDKASTSYLLSHPE-----------GGRVAVLAVGGPLEALEAKPGTVSLRLRNQKGFVKLSLEHG-ASLVPVFSFGENDLFQQFPNPPGSWVRRMQEALQ----RILSVALPLFHGR------LGLLIPFRVPIHTVVGAPIPVQR-SPRPTREQVNRLHELYVERLTQLFEEHKMRYGVPADQHLVFI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZV4-1", "uniprot_id": "MOGT1_MOUSE", "id": "Q91ZV4-1", "name": "2-acylglycerol O-acyltransferase 1", "aln": "----------------------------------------------------MMVEFAPLNTPLARCLQTAAVLQWVLSFLLLVQVCIGIMVMLVLYN-YWFLYIPYLVWFYYDWR--TPEQGGRRWNWVQSWPVWKYFKEYFPICLVKTQDLDPGH------------------------------------------NYIFGFHPHGIFVPGAFGNFCTKYSDFKKLFPGFTSYLHVAKIWFCFPLFREYLMSNGPVSVSKESLSHVLSKDG-----------GGNVSIIVLGGAKEALEAHPGTFTLCIRQRKGFVKMALTHG-ASLVPVFSFGENDLYKQINNPKGSWLRTIQDAMY----DSMGVALPLIYARGIFQHYFG-IMPYRKLIYTVVGRPIPVQQ-TLNPTSEQIEELHQTYLEELKKLFNEHKGKYGIPEHETLVFK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K7Z7-1", "uniprot_id": "A0A0G2K7Z7_RAT", "id": "A0A0G2K7Z7-1", "name": "Acyltransferase", "aln": "----------------------------------------------------MMVEFEPSNSLLARCLQTAAMLQGILVILVLIPGSIGIMVMLILYN-YWFLYIPYLVWCYYDRR--TPEQGGRRWSWVQNWTVWKYFMDYFPIHLVKTQDLDPAH------------------------------------------NYIFGFHPHGIFVFGAFGNFCTNYSDFKKLFPGFTSYLHVAVSWFWLPLFREYALSNGPVSVSKRSLSHVMSKEG-----------GGNISVIVIGGAKELLESFPGRYSLCLLQRKGFVKIALTHG-AHLVPVFSFGENELYSQVDNPKGSWLRTAQDKVY----NLTGLALPLFYARGIFQNSFG-LMPYRKLIYTVVGRPIPVQK-TLHPTPEQIDELHQTYMEELRKLFNEHKGKYGIPEHETLVFK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96PD6-1", "uniprot_id": "MOGT1_HUMAN", "id": "Q96PD6-1", "name": "2-acylglycerol O-acyltransferase 1", "aln": "----------------------------------------------------MKVEFAPLNIQLARRLQTVAVLQWVLKYLLLGPMSIGITVMLIIHN-YLFLYIPYLMWLYFDWH--TPERGGRRSSWIKNWTLWKHFKDYFPIHLIKTQDLDPSH------------------------------------------NYIFGFHPHGIMAVGAFGNFSVNYSDFKDLFPGFTSYLHVLPLWFWCPVFREYVMSVGLVSVSKKSVSYMVSKEG-----------GGNISVIVLGGAKESLDAHPGKFTLFIRQRKGFVKIALTHG-ASLVPVVSFGENELFKQTDNPEGSWIRTVQNKLQ----KIMGFALPLFHARGVFQYNFG-LMTYRKAIHTVVGRPIPVRQ-TLNPTQEQIEELHQTYMEELRKLFEEHKGKYGIPEHETLVLK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08650-1", "uniprot_id": "DGAT2_YEAST", "id": "Q08650-1", "name": "Diacylglycerol O-acyltransferase 1", "aln": "---------MSGTFNDIRRRKKEEGSPTAGITERHENKSLSSIDKREQTLKPQLESCCPLATPFERRLQTLAVAWHTSSFVLFS----IFTLFAISTPALWVLAIPYMIYFFFDRSPATGEVVNRYSLRFRSLPIWKWYCDYFPISLIKTVNLKPTFTLSKNKRVNEKNYKIRLWPTKYSINLKSNSTIDYRNQECTGPTYLFGYHPHGIGALGAFGAFATEGCNYSKIFPGIPISLMTLVTQFHIPLYRDYLLALGISSVSRKNALRTLSK--------------NQSICIVVGGARESLLSSTNGTQLILNKRKGFIKLAIQTGNINLVPVFAFGEVDCYNVLSTKKDSVLGKMQLWFK----ENFGFTIPIFYARGLFNYDFG-LLPFRAPINVVVGRPIYVEKKITNPPDDVVNHFHDLYIAELKRLYYENREKYGVPDAELKIVG-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A1Z739-1", "uniprot_id": "A1Z739_DROME", "id": "A1Z739-1", "name": "Acyltransferase", "aln": "----------------------------------------------------MTIEWAPLRVPLERRLQTLVTSFFTYTFFTLPISSCLAVAILLYYGEMFVRSLLLIYFVKIYLDYKRNYGIMEGNGWLFYRSNWR-YRNYFPVELVKTAELPPNR------------------------------------------NYIVASFPHGILGTGTCINMSLDIDNWLSLYPHVRPKIATLDHHFKTPFLRDILRWWGMVSVSKESLSYLLSKSNDPMHKDNRDGFTSNAVAVLVGGAKEAMDSHPGQYILTLKDRKGFVKMAVRTG-SSIVPSLSFGEVDIFDQVANPPDSSLRRFQNVVK----KFTGISPLLPKGRGIFNYNYG-ILPHRRRIVQVVGSPIDVER-CETPDPEYVDKIHGQVIDALARMFDEYKEKYTPNSKHIKLIIQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : . . * .::*: ::** :: . .*: .***: . : . :* . : * *. *: * . . :. .. : ** * . .. : : .:.**:: :: * ::* :*** : : * . . . ::.. : :** .: : * . : : * :: : . ", "identical_positions": 28, "similar_positions": 70, "identity": "6.21%" }, { "cls_id": "homologset.agr.SGD:S000005772", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ERI6-1", "uniprot_id": "RDH14_MOUSE", "id": "Q9ERI6-1", "name": "Retinol dehydrogenase 14", "aln": "---------------------------------------------------------------------------------MAVASVAAALLAALGGALWLAARRFSGPRNQRQQGGGDP-GLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRQELCQAGGAGPD-G--TD--GQLVVKELDLASLRSVRAFCQELLQEEPR-------------LDVLINNAGVFHCP-YTKTEDGFEMQFGVN---HLGHFLLTNLLLGLLKSSAP----SRIVVVSSKLYKY-------GEINFEDLNSE------QSYNKSF-CYSRSKLA---NILFTRELARRLEGTN--VTVNVLHPG-IVRTNLGRHIHIP------LLARPLFNLV-------------------------------SWAFFK-----------------------TP----------------LEGAQTSIYLACSPDVEGVS----------------------------------GRYF-GDCKEEELLPKAMDES-----------VARKLWDISEVMVGILK----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HBH5-1", "uniprot_id": "RDH14_HUMAN", "id": "Q9HBH5-1", "name": "Retinol dehydrogenase 14", "aln": "---------------------------------------------------------------------------------MAVA-TAAAVLAALGGALWLAARRFVGPRVQRLRRGGDP-GLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPG--VSGVGELIVRELDLASLRSVRAFCQEMLQEEPR-------------LDVLINNAGIFQCP-YMKTEDGFEMQFGVN---HLGHFLLTNLLLGLLKSSAP----SRIVVVSSKLYKY-------GDINFDDLNSE------QSYNKSF-CYSRSKLA---NILFTRELARRLEGTN--VTVNVLHPG-IVRTNLGRHIHIP------LLVKPLFNLV-------------------------------SWAFFK-----------------------TP----------------VEGAQTSIYLASSPEVEGVS----------------------------------GRYF-GDCKEEELLPKAMDES-----------VARKLWDISEVMVGLLK----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NAK9-1", "uniprot_id": "A0A8M1NAK9_DANRE", "id": "A0A8M1NAK9-1", "name": "", "aln": "------------------------------------------------------------------------------------MSAAVVLAAVLGGGVFFIARRIIFRRKALRLMSYPP-ALMRGKTVIVTGANCGIGKATAAELLKLQARVIMACRDRQRAEDAARDIQNQAGTSQ-------------GEIVIKHLDLASLQSVRRFCEEVIREEPR-------------IDVLINNAGLYQCP-YSKTEEGFEMQLGVN---HLGHFLLTNLLLDLLKQSSP----SRVVVVSSKLYKY-------GSINFEDLNSE------QSYNKSF-CYSQSKLA---NLLFTRELARRLDGTE--VTVNALTPG-IVRTRLGRHVNIP------LLIKPLFWLV-------------------------------SWLFFK-----------------------SP----------------LEGAQTPLYLACSPEVEGVS----------------------------------GKCF-ANCEEEQLLSKATDDH-----------AAKRLWDLSESMVGLRR----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58HZ16-1", "uniprot_id": "A0AC58HZ16_DANRE", "id": "A0AC58HZ16-1", "name": "", "aln": "-----------------------------------------------------------------------MAGIIKSSETLGSSGRSPSFGIKR-QDLAGTRSGLLLLRRWISGGVCRCRVRLDGKTVVITGSNTGIGKETARDMARRGARVVMACRDLSKAEKAAAEIRRSTGNAD---------------IVVRHLNLASLHSVRQFAHQYTATEDR-------------LDILINNAGVMMCP-KSLTEDGYETQFAVN---HLGHFLLTVLLLDMLKKSSP----SRVINVSSITHKG-------GKIHFDDLNFN------KAPYDSLVSYRQSKLA---NLLFTRELARRIKGSG--VSVFSLHPG-VIRTELGRYVQTRH-----PLLSGLLSIP-------------------------------ALLLMK-----------------------TP----------------YQGAQTSIYCATADGLEIHS----------------------------------GCYF-SDCALKEPAPEGKDDL-----------AALRLWEISAKLVGYSEED--------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7TEZ4-1", "uniprot_id": "A0A8N7TEZ4_DANRE", "id": "A0A8N7TEZ4-1", "name": "", "aln": "-------------------------------------------------------------------------MLFTSACEMKDPGTS-SDGVNYGAVLALLVISFVLLRKWIAGGVCKSHARLDGKTVVITGANTGIGRETAKDMAYRGARVVMACRDLIRAEDAAEYIRRCTGNGN---------------VVIRHLNLASLYSVREFAKEFIATEER-------------LDILINNAGVMMCP-KCVTEDRFETQLAVN---HLGHFLLTNLLLEMLKRSSP----SRVVNVSSIAHVG-------GKIEFDDLFFD------KRPYSPLVSYKQSKLA---NVLFSRELARRMKGTG--VSSYCLHPG-VIRTDLSRHILSWF-----PMLKTILYLP-------------------------------SMLLMK-----------------------TP----------------WQGAQTTIYCAVTEGLESKS----------------------------------GSYF-SDCAEKDPAPEGKDDL-----------VARRLWEESVRLVGLNDTLN-------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BG52-1", "uniprot_id": "A0A8M2BG52_DANRE", "id": "A0A8M2BG52-1", "name": "", "aln": "--------------------------------------------------------------------------MQDYANAVKEFVEDHYTGVTF---VLITGVGLFGFRRWLAGGVCRSKARLNGKTVLITGGNTGIGKETAVDMAKRGARVILACRDMGRAHKAAEEVRKRSGNEN---------------VTVKMLDLASLQSVRDLVKDVQQSEKR-------------LDILINNAGVMMCP-KWHTDEGFEMQIGVN---HLGHFLLTNLLLDLLKKSAP----SRIVNVASVAHER-------GKINFNDINMD------KD-YDPYQSYYRSKLA---NVLFTRELAVKLRDTG--VTTYALHPG-VIRTELVRHVVS-------NLWRKLMILP-------------------------------FYFFFK-----------------------NP----------------WQGAQTTIYCAVDESLKHSS----------------------------------GLYY-SDCAPKETAPQGRDDV-----------AARRLWDLSASMVGLA-----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z729-1", "uniprot_id": "A1Z729_DROME", "id": "A1Z729-1", "name": "NADP-retinol dehydrogenase", "aln": "---------------------------------------------------------------------------------MCIFIDCLLS--PLIMWPATIGVGIYFLKEYMQGGKFTKDTDETGKVFIVTGANTGIGKETALEIARRGGTVYLACRDMNRCEKARKDIIKETNNQN---------------IFSRELDLSSLDSIRKFVDGFKKEQPK-------------LHVLINNAGVMRCP-KTLTKDGYELQLGVN---HIGHFLLTNLLLDVLKNSAP----SRIVVVSSLAHAR-------GSINVADLNSE------KSYDEGL-AYSQSKLA---NVLFTRELAKRLEGSG--VTVNALHPG-VVDTELARNWAFFQTN----LVKFFLKPM-------------------------------IWPLLK-----------------------TP----------------KSGAQTSIYAALDPELKNIS----------------------------------GLYF-SDCKPKPVASGALDDK-----------VAKFLWAESEKWTGLDKLEANN-----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KFB3-1", "uniprot_id": "A0A0B4KFB3_DROME", "id": "A0A0B4KFB3-1", "name": "NADP-retinol dehydrogenase", "aln": "---------------------------------------------------------------------------------MEIVIRFLQSIAPVFLAHGIVGIIAFCVRLYMQGGKFRKQTDETGKVAIVTGGNTGLGKETVMELARRGATVYMACRNKEKVERARREIVKETGNSN---------------VFSRECDLSSLDSIRKFAENFKKEQRV-------------LHILINNAGVFWEP-HRLTKEGFEMHLGVN---HIGHFLLTNLLLGVLERSAP----SRVVVVASRAHER-------GQIKVDDINSS------DFYDEGV-AYCQSKLA---NILFTRELAKRLEGTG--VTVNALNPG-IADTEIARNMIFFQTKFAQYVVETILRPL-------------------------------LWAVMK-----------------------TP----------------KNGAQTTLYAALDPDLERVS----------------------------------GQYF-SDCALAPVAPAALDDQ-----------MAQWLWAQSEKWAKIAL----------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W404-1", "uniprot_id": "Q9W404_DROME", "id": "Q9W404-1", "name": "", "aln": "----------------------------------------------------MSEAATPPGSVPGTVFPPGFDPTAESVEKTLCFRGFWAWAVLIFLIVLGILLFMWLLRKCIQGPAYRKANRIDGKVVIVTGCNTGIGKETVLELAKRGARVYMACRDPGRCEAARLDIMDRSRNQQ---------------LFNRTLDLGSLQSVRNFVERFKAEESR-------------LDILINNAGVMACP-RTLTADGFEQQFGVN---HLGHFLLTNLLLDRLKHSSP----SRIVVVSSAAHLF-------GRINREDLMSE------KNYSKFFGAYSQSKLA---NILFTLKLSTILKDTG--VTVNCCHPG-VVRTEINR--HFSGPG----WMKTALQKG-------------------------------SLYFFK-----------------------TP----------------KAGAQTQLRLALDPQLEGST----------------------------------GGYY-SDCMRWPLFPWVRNMQ-----------TADWLWRESEKLLGLPPLEPPPPVQSPTQNGNGTQNGNGSSSASASASSNNPASREMQSVETVVVNRS-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1N3S3-1", "uniprot_id": "A0A8M1N3S3_DANRE", "id": "A0A8M1N3S3-1", "name": "NADP-retinol dehydrogenase", "aln": "---------------------------------------------------------------------------------------------------------MQAMRNMFC--SWSSAARLDGKTVLITGANTGIGKETAIDLAKRGARIIMACRDMEKAEAALKEVKDSSGNQD---------------VFISSLDLSDSKSIRGFAEKINKEEKQ-------------VNILINNAGVMVCP-YGKTADGFEMQIGVN---HMGHFLLTYLLLDLIKRSAP----ARIINVSSTAHQW-------GTINLEDINSE------KNYDKQK-AYCQSKLA---NVLFTRSLAKRLEGTG--VTAYSLHPG-VVQTDLWRHLSKP---------QQAVMWF-------------------------------TKPFTK-----------------------TS----------------VQGAQTSIYCAVDPELQTES----------------------------------GKYY-SDCAPAKAAKAAMDDE-----------VAQRLWELSCRMLNITWE---------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6Z277-1", "uniprot_id": "A0A8M6Z277_DANRE", "id": "A0A8M6Z277-1", "name": "NADP-retinol dehydrogenase", "aln": "-----------------------------------------------------------------------------------------------------MALVMSLHRDFFGG-QWSSNARLDDKTIIITGANTGIGKETTKDLAKRGPRIIMACRDVEKAERAQREIMEESGNQN---------------IVIRKLDLSDTRSIREFAEVINSEERS-------------LHLLINNAGVMMCP-YSKTADGFEMQFGVN---HLGHFLLTFLLIDLLKRSAP----SRIINLSSMAHSW-------GTITLDDINSE------RNYHSRR-AYGQSKLA---NILFTRSLAKKLKDTG--VTSYAVHPG-IVRTELKRHMNLG---------LLIMWKV-------------------------------VRPFTK-----------------------TP----------------VQGAQTTIYCAVQPELDAES----------------------------------GGYY-SDCRPSRCTRAARDDE-----------MAEKLWELSCNMLGILWD---------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9QYF1-1", "uniprot_id": "RDH11_MOUSE", "id": "Q9QYF1-1", "name": "Retinol dehydrogenase 11", "aln": "------------------------------------------------------------------------------------MFGFLLLLS----LPFILYLVTPKIRKMLSSGVCTSNVQLPGKVAIVTGANTGIGKETAKDLAQRGARVYLACRDVDKGELAAREIQAVTGNSQ---------------VFVRKLDLADTKSIRAFAKDFLAEEKH-------------LHLLINNAGVMMCP-YSKTADGFEMHIGVN---HLGHFLLTHLLLEKLKESAP----SRIVNLSSLGHHL-------GRIHFHNLQGE------KFYSAGL-AYCHSKLA---NILFTKELAKRLKGSG--VTTYSVHPG-TVHSELTRYSSI----------MRWLWQL-------------------------------FFVFIK-----------------------TP----------------QEGAQTSLYCALTEGLESLS----------------------------------GSHF-SDCQLAWVSYQGRNEI-----------IARRLWDVSCDLLGLPVDW--------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TC12-1", "uniprot_id": "RDH11_HUMAN", "id": "Q8TC12-1", "name": "Retinol dehydrogenase 11", "aln": "--------------------------------------------------------------------------------MVELMFPLLLLL-----LPFLLYMAAPQIRKMLSSGVCTSTVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQ---------------VLVRKLDLSDTKSIRAFAKGFLAEEKH-------------LHVLINNAGVMMCP-YSKTADGFEMHIGVN---HLGHFLLTHLLLEKLKESAP----SRIVNVSSLAHHL-------GRIHFHNLQGE------KFYNAGL-AYCHSKLA---NILFTQELARRLKGSG--VTTYSVHPG-TVQSELVRHSSF----------MRWMWWL-------------------------------FSFFIK-----------------------TP----------------QQGAQTSLHCALTEGLEILS----------------------------------GNHF-SDCHVAWVSAQARNET-----------IARRLWDVSCDLLGLPID---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BYK4-1", "uniprot_id": "RDH12_MOUSE", "id": "Q8BYK4-1", "name": "Retinol dehydrogenase 12", "aln": "-----------------------------------------------------------------------------------MLFILVLLTS----FLSILYLTAPSIRKFFAGGVCTTNVQIPGKVVVITGANTGIGKETARELARRGARVYIACRDVLKGESAASEIRADTKNSQ---------------VLVRKLDLSDTKSIRAFAERFLAEEKK-------------LHILINNAGVMMCP-YSKTTDGFETHFGVN---HLGHFLLTYLLLERLKESAP----ARVVNLSSIAHLI-------GKIRFHDLQGQ------KRYCSAF-AYGHSKLA---NLLFTRELAKRLQGTG--VTAYAVHPG-VVLSEITRNSYL----------LCLLWRL-------------------------------FSPFFK-----------------------ST----------------SQGAQTSLHCALAEDLEPLS----------------------------------GKYF-SDCKRMWVSSRARNKK-----------TAERLWNVSCELLGIQWE---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZEP9-1", "uniprot_id": "D3ZEP9_RAT", "id": "D3ZEP9-1", "name": "NADP-retinol dehydrogenase", "aln": "-----------------------------------------------------------------------------------MLVILVLLTS----FFSILYLATPSIRKFFAGGVCTTKVQIPGKVVVITGANTGIGKETARELARRGARVYIACRDVLKGESAASEIRADTKNSQ---------------VLVRKLDLSDTKSIRTFAEGFLAEEKK-------------LHILINNAGVMMCP-YSKTVDGFETHFGVN---HLGHFLLTYLLLGRLKESAP----ARVINLSSVAHLG-------GKIRFHDLQSK------KRYCSGF-AYSHSKLA---NVLFTRELAKRLQGTG--VTAYVVHPG-CVLSEITRHSFL----------MCLLWRL-------------------------------FSPFFK-----------------------SP----------------WQGAQTSLHCALEEGLEPLS----------------------------------GKYF-SDCKRTWVSPRARNKK-----------TAERLWNVSCELLGIQWE---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96NR8-1", "uniprot_id": "RDH12_HUMAN", "id": "Q96NR8-1", "name": "Retinol dehydrogenase 12", "aln": "-----------------------------------------------------------------------------------MLVTLGLLTS----FFSFLYMVAPSIRKFFAGGVCRTNVQLPGKVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTKNSQ---------------VLVRKLDLSDTKSIRAFAEGFLAEEKQ-------------LHILINNAGVMMCP-YSKTADGFETHLGVN---HLGHFLLTYLLLERLKVSAP----ARVVNVSSVAHHI-------GKIPFHDLQSE------KRYSRGF-AYCHSKLA---NVLFTRELAKRLQGTG--VTTYAVHPG-VVRSELVRHSSL----------LCLLWRL-------------------------------FSPFVK-----------------------TA----------------REGAQTSLHCALAEGLEPLS----------------------------------GKYF-SDCKRTWVSPRARNNK-----------TAERLWNVSCELLGIRWE---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N061-1", "uniprot_id": "A0A8M1N061_DANRE", "id": "A0A8M1N061-1", "name": "NADP-retinol dehydrogenase", "aln": "-----------------------------------------------------------------------------------MMLALVAFAAGLGLVALILRLLSPQIRKYAAGGSCRSTVRLDGKVALVTGANSGIGKETALDLASRGARVILACRDLEKAEEAAAEIRTRVGGAK---------------VEVRELDLADCCSIRAFAQRFLREVDH-------------LHILINNAGVMMCP-YMKTADGFEMQIGVN---HLGHYLLTYLLIGLLKRSAP----SRIVVVSSLAHNF-------GWIRFHDLHSQ------GSYNSGL-AYCQSKLA---NVLFTRELARRLQGSN--VTVNSVHPG-TVRSELVRHSTL----------MSLLFAF-------------------------------FSMFLK-----------------------SP----------------KEGAQTSIYCAVAEELQSIS----------------------------------GKHF-SDCAPAFVAPQGRSEE-----------TARKLWDVSCELLGIEWD---------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8NBN7-1", "uniprot_id": "RDH13_HUMAN", "id": "Q8NBN7-1", "name": "Retinol dehydrogenase 13", "aln": "------------------------------------------------------------------------------------MSRYLLPLS----ALGTVAGAAVLLKDYVTGGACPSKATIPGKTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNHH---------------VNARHLDLASLKSIREFAAKIIEEEER-------------VDILINNAGVMRCP-HWTTEDGFEMQFGVN---HLGHFLLTNLLLDKLKASAP----SRIINLSSLAHVA-------GHIDFDDLNWQ------TRKYNTKAAYCQSKLA---IVLFTKELSRRLQGSG--VTVNALHPG-VARTELGRHTGIHG----STFSSTTLGPI-------------------------------FWLLVK-----------------------SP----------------ELAAQPSTYLAVAEELADVS----------------------------------GKYF-DGLKQKAPAPEAEDEE-----------VARRLWAESARLVGLEAPS-------------VREQPLPR-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CEE7-1", "uniprot_id": "RDH13_MOUSE", "id": "Q8CEE7-1", "name": "Retinol dehydrogenase 13", "aln": "------------------------------------------------------------------------------------MSRFLLPVS----VVGTVIGGTVLLKDYVAGGACPSKATIPGKTVIVTGANTGIGKQTALELAKRGGNVILACRDMEKCEVAAKDIRGETLNPR---------------VRAERLDLASLKSIREFARKVIKEEER-------------VDILVNNAAVMRCP-HWTTEDGFEMQFGVN---YLGHFLLTNLLLDKLKASAP----SRIINLSSLAHVA-------GHIDFEDLNWQ------MKKYDTKAAYCQSKLA---VVLFTKELSHRLQGSG--VTVNALHPG-VARTELGRHTGMHN----SAFSGFMLGPF-------------------------------FWLLFK-----------------------SP----------------QLAAQPSTYLAVAEELENVS----------------------------------GKYF-DGLREKAPSPEAEDEE-----------VARRLWTESARLVGLAMAHGS----------PGRGHAIPR-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AG15-1", "uniprot_id": "A0A8I6AG15_RAT", "id": "A0A8I6AG15-1", "name": "", "aln": "------------------------------------------------------------------------------------MNRFLLPVS----VVGTVIGGTVLLKDYVAGGACPSKATIPGRTVIVTGANTGIGKQTALELAKRGGNIILACRDREKCEAAAKDIRGETLNPR---------------VRAEHLDLASLKSIREFAGKIIKEEER-------------VDILVNNAAVMRCP-HWTTKDGFEMQFGVN---HLGHFLLTNLLLDKLKASAP----SRIINLSSLAHVA-------GHIDFEDLNWQ------IKKYDTKAAYCQSKLA---VVLFTKELSRRLQGTG--VTVNALHPG-VARTELGRHTGMHN----SAFSGFMLGAYKEKPSLTIDSGPQGFSKRNVTLVCHTHHFFDLFILCRDGNASFPRNCLQQDHNTFLISPVSPGYKRTYRCFVSPKVNSYLWSLPSDPLELLVPGPSVSPIVVWVTVAAVCFLIFFLLLLYLCHHWAKCKTSSAKTR-TQVKYKSSSPAMDNDEKIKYDELECIQPENYCQVDTKKLSAVEDSKEVTYAQLCQEIFLENMDSLPSNTLHHMSTQTCVYATLRLSQEESQS----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UX07-1", "uniprot_id": "DHR13_HUMAN", "id": "Q6UX07-1", "name": "Dehydrogenase/reductase SDR family member 13", "aln": "------------------------------------------------------------------------------------MEALLLGAG------LLLGAYVLVYYNLVKAPPCGGMGNLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFDLRQESGNNE---------------VIFMALDLASLASVRAFATAFLSSEPR-------------LDILIHNAGISSC---GRTREAFNLLLRVN---HIGPFLLTHLLLPCLKACAP----SRVVVVASAAHCR-------GRLDFKRLDRP---VVG--WRQELRAYADTKLA---NVLFARELANQLEATG--VTCYAAHPG-PVNSELFLRHVPG-------WLRPLLRPL-------------------------------AWLVLR-----------------------AP----------------RGGAQTPLYCALQEGIEPLS----------------------------------GRYF-ANCHVEEVPPAARDDR-----------AAHRLWEASKRLAGLGPGEDAE-PDEDPQSEDSEAPSSLSTPHPEEPTVSQPYPSPQSSPDLSKMTHR-IQAKVEPEIQLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SS80-1", "uniprot_id": "DHR13_MOUSE", "id": "Q5SS80-1", "name": "Dehydrogenase/reductase SDR family member 13", "aln": "------------------------------------------------------------------------------------MEMLLLGAG------LLLGAYVLVYYNLVKAPSCGGIGSLRGRTVVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNE---------------VIFMALDLASLASVQAFATAFLSSEPR-------------LDVLIHNAGISSC---GRTRETFNLLLRVN---HVGPFLLTHLLLPRLRSCAP----SRVVIVSSAAHRR-------GRLDFTRLDCP---VVG--WQQELRAYADSKLA---NVLFARELATQLEGTG--VTCYAAHPG-PVNSELFLRHLPG-------WLRPILRPL-------------------------------AWLVLR-----------------------AP----------------QGGAQTPLYCALQEGIEPLS----------------------------------GRYF-ANCHVEEVSPAARDDQ-----------AAQRLWKATKKLAGLAPGDDDDDPDEEPEPEDPRAPSSQSAPSPEKTTVSGPSHSYQGSQDLSKLTQRRIQVKDEPTP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1N3D5-1", "uniprot_id": "A0A8M1N3D5_DANRE", "id": "A0A8M1N3D5-1", "name": "", "aln": "------------------------------------------------------------------------------------MSVLLSVLV------GVLAAYVLIYYCLFKGARYKGNATLNGKTAIVTGSNTGIGKTTALDLARRGARVILACRNQERAEAAVYDIRKESGNSE---------------VLYMHLDLASLQSVRDFAETFLKTEPR-------------LDLLINNAGLIAS---GRTEDGFGMAFGVN---HLGHFLLTLLLLDRLKQSEN----SRVVNVSALLHRL-------GSLDFNLLNTQKDLVTGQSYWHAIKAYCHSKLC---NVLFTRELANRLEGTS--VTCYCLHPG-VISTEIG-RYMGP-------LQKLLCLPM-------------------------------SKLFFL-----------------------DP----------------EAGAQTTLYCALQEGLEPLS----------------------------------GRYF-SSCALQEVGALGRDDA-----------LARKLWDVSERLCGLS-----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N3E3-1", "uniprot_id": "A0A8M1N3E3_DANRE", "id": "A0A8M1N3E3-1", "name": "", "aln": "------------------------------------------------------------------------------------MFFLLLTCG------GLLAVYLLLRVTVMKMPRCTSTARLDGKTVIVTGANTGIGKATAMDLARRGARVILACRDEGRAQAAVTDIQRETGSKE---------------VLYMHLDLASLKSVRSFAENFLKKESR-------------LDILINNAGLVIG---GKTEDGFGRMFGVN---HLGHFLLTDLLLKRLKECGP----SRIVTVSSMAHAW-------GKMDFNCINAQKDLGKGDSALGLLMLYSHSKLC---NVLFTHELAKRLKGTN--VTCYSLHPG-AIKTELS-RHSNI-------WWSLFMAPI-------------------------------FLLFFK-----------------------DV----------------VSGAQTSLHCALQEGIEPLS----------------------------------GRYF-SGCAVQNVSAKARDDA-----------AAKKLWEISERFVGLA-----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NC65-1", "uniprot_id": "A0A8M1NC65_DANRE", "id": "A0A8M1NC65-1", "name": "", "aln": "------------------------------------------------------------------------------------MYLLYTIIS--------ALVCFLVLKWMKRRRYCTDLKRLDGKTVLITGGNSGIGKETAVALAMRGARVIIACRDEEKARKAVREIKARSHNMN---------------VLHMEVDLANMRSIREFSKTFLQKEKR-------------LDILINNAG-MPGV-LDWTDDNFSMCFGVN---HLGHFLLTNLLLPRLKESSP----SRVINLTCSSYKY-------QKLNFQDLNYN---------LFPFFTYCRSKLA---NIYFTQELARMMEGKG--VTAYAVHPG-YVRSRWTCHFSVLY--------QILAQVV-------------------------------MFMFFVS---------------------------------------CEAGAQTVVYCAVSDEVLPRN----------------------------------GGYF-TDCRPAPLKAFARDSG-----------VAKKLWEASERLVKLA-----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VE80-1", "uniprot_id": "Q9VE80_DROME", "id": "Q9VE80-1", "name": "", "aln": "-----------------------------------------------------------------------MGFIFGWLSTEHYVRDIFLMTSVA---AIVATLMSIRFYLRITAGRCFTETKMEGKTVIITGANSGIGKETAKDLAGRGARIIMACRNLETANAVKDEIVKETKNNK---------------ILVKKLDLGSQKSVREFAADIVKTEPK-------------IDVLIHNAGMALAFRGQTSEDGVELTMATN---HYGPFLLTHLLIDVLKKSAP----ARIVIVASELYRL-------SSVNLAKLN-PIGT------FPAAYLYYVSKFA---NIYFARELAKRLEGTK--VTVNFLHPG-MIDSGIWRNVPFP--------LNLPMMAIT-------------------------------KGFFK-----------------------TT----------------KAGAQTTIYLATSNEVANVS----------------------------------GKYF-MDCKEATLNAAALDEE-----------KGLKIWEESVKIVKLTPQDPKI-----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1PEE4-1", "uniprot_id": "A0A8M1PEE4_DANRE", "id": "A0A8M1PEE4-1", "name": "", "aln": "---------------------------------------------------------------------------MNWEWSDLYSHPLWMVSSV-----ILALVVRAQRKSLWNPRACLVR--LKGKTAIVTGANTGIGKFIALDFARRGARVILACRSEARGTAALKEIRESTGNHD---------------VHLRLLDTSSMESVRKFAAQILKEEKE-------------LHILVNNAG-ASGLPIQITADGLEITFATN---HVGPFLLTSLLLDLLKKSAP----ARIVNVASAMHWK-------GDVDFAHFHGEKLN------HGVNRVYNHTKLH---NVIWTNELARRLQGTG--VTANSLHPG-VVMTEVMRNYNFI--------LRLLFNLIG-------------------------------FFFFK-----------------------TA----------------EEGAFSPIYCAVAEENEGIT----------------------------------GKYFDSDCSLVLPAPPARDPA-----------LGVKEYEFCERLIAKL-----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABJ3HKQ2-1", "uniprot_id": "A0ABJ3HKQ2_MOUSE", "id": "A0ABJ3HKQ2-1", "name": "Polyprenol dehydrogenase", "aln": "-----------------------------------------------------------------------------------MSTLRALRAVLCVYAVGIAVALAQLLRRLRGDFRPPVLPPQPGRVAIVTGATAGIGRSTARQLARLGMCVVVAGNDEHCGQEVVSSIRAEMGSDR---------------AHFLPLDLASLASVRGFARDFRALGLP-------------LHLLVNNAGVMLEP-RAETEDGFERHLGVN---FLGHFLLTLLLLPALRASGAEGRGSRVVTVGSATHYV-------GTVDMADLHGR-------HAYSPYAAYAQSKLA---LALFALQLQRILDARGDPVTSNMADPG-VVDTELYRHAGWVL--------RTVKRFLG-------------------------------WLVFK-----------------------SP----------------EEGAWTLVYAAAAPELEGVG----------------------------------GRYL-RDEAEAEPLGTARDQE-----------LQRRLWAEGLRLTGAGGGDSDGVAW--------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8J8YGQ6-1", "uniprot_id": "A0A8J8YGQ6_RAT", "id": "A0A8J8YGQ6-1", "name": "Polyprenol dehydrogenase", "aln": "-------------------------------------------------------------------------------------MLAALWAALRVYAVGVAVTMVQLLRRLRGGFRPPELPLQADRVAIVTGATRGVGLSTACQLARLGMRVIVAGNDEHRGHEVVARIQEESGPES---------------AHFLFLDLASLSSVRSFVRNFEATALP-------------LHLLINNAGVMLDP-SGNTKDGFERHVGVN---FLGHFLLTSLLLPALRASGHQGRKSRVITVCSSTHWV-------GQADVARLLGQS------PAPCALAAYAGSKLA---LALFSLRLQRLLSALGDPVTANIVDPG-VVDTALFAHAGWGT--------RAVQRFLG-------------------------------WLLFK-----------------------TP----------------DEGAWTSVYAAASPKLEGIG----------------------------------GRYL-RDEAEAEVLGAARDLE-----------LQGHLWAESCRLTGAAWVAVGE-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B8A5W4-1", "uniprot_id": "DHRSX_DANRE", "id": "B8A5W4-1", "name": "Polyprenol dehydrogenase", "aln": "----------------------------------------------------------------------------------MWRLLHCILGFIRLYLDGVKVLLYQLFNKS---FRLPDLPEQNGKVAIVTGGTRGMGYEISRHLVSLDMHVIIAGNEEEEGLAAVKKIQEELNQGK---------------VEFMYLDLASLTSVRQFVQRYNAKGLP-------------LHVLVNNAGVMLVP-ERRTEDGFELHFGLN---YLGHFLLTNLLLGALRKTGKPGKCSRIVIMSSATHYG-------GRLTLDDLQGR-------LCYSSHAAYAQSKLA---LLLLSYHLQEQLLVRGDPVTVNAVDPG-MVDTALYDNLCSPA--------QVAKKPFA-------------------------------KLLFR-----------------------TP----------------AEGASTAIYAAAASELEGIG----------------------------------GLYL-YNGRKTESSALSYDKR-----------LQTKLWKQSCALVGLK-----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8N5I4-1", "uniprot_id": "DHRSX_HUMAN", "id": "Q8N5I4-1", "name": "Polyprenol dehydrogenase", "aln": "-----------------------------------------------------------------------------------MSPLSAARAALRVYAVGAAVILAQLLRRCRGGFLEPVFPPRPDRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLNDK---------------VEFLYCDLASMTSIRQFVQKFKMKKIP-------------LHVLINNAGVMMVP-QRKTRDGFEEHFGLN---YLGHFLLTNLLLDTLKESGSPGHSARVVTVSSATHYV-------AELNMDDLQSS-------ACYSPHAAYAQSKLA---LVLFTYHLQRLLAAEGSHVTANVVDPG-VVNTDVYKHVFWAT--------RLAKKLLG-------------------------------WLLFK-----------------------TP----------------DEGAWTSIYAAVTPELEGVG----------------------------------GHYL-YNEKETKSLHVTYNQK-----------LQQQLWSKSCEMTGVLDVTL-------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91WL8-1", "uniprot_id": "WWOX_MOUSE", "id": "Q91WL8-1", "name": "WW domain-containing oxidoreductase", "aln": "MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQ-VFFVDHINKRTTYLDPRLAFTVDD-NPTKPTTRQRYDGSTTAMEILQGRDFTGKVVLVTGANSGIGFETAKSFALHGAHVILACRNLSRASEAVSRILEEWHKAK---------------VEAMTLDLAVLRSVQHFAEAFKAKNVS-------------LHVLVCNAGTFALP-WGLTKDGLETTFQVN---HLGHFYLVQLLQDVLCRSSP----ARVIVVSSESHRFTDINDSSGKLDLSRLSPP------RSDYWAMLAYNRSKLC---NILFSNELHRRLSPRG--VTSNAVHPGNMMYSAIHRNSWVYK---------LLFTLAR--------------------------------PFTKS---------------------------------------MQQGAATTVYCAVAPELEGLG----------------------------------GMYF-NNCCRCLPSEEAQSEE-----------TARALWELSERLIQDRLGSPSS-----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LQK5-1", "uniprot_id": "A0ABK0LQK5_RAT", "id": "A0ABK0LQK5-1", "name": "WW domain-containing oxidoreductase", "aln": "MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQ-VFFVDHINKRTTYLDPRLAFTVDD-NPTKPTTRQRYDGSTTAMEILQGRDFTGKVVLVTGANSGIGFETAKSFALHGAHVILACRNMSRASEAVSRILEEWHKAK---------------VEAMTLDLAVLRSVQHFAEAFKAKNVP-------------LHILVCNAGTFALP-WSLTKDGLETTFQVN---HLGHFYLVQLLQDVLCRSAP----ARVIVVSSESHRFTDINDSSGKLDLSRLSLS------SSDYWAMLAYNRSKLC---NILFSNELHRLLSPRG--VTSNALHPGNMMFSAIHRNSWVYK---------LLFTLAR--------------------------------PFTKS---------------------------------------MQQGAATTVYCAVAPELEGLG----------------------------------GMYF-NNCCRCLPSEEAQNEE-----------TARALWELSERLIQDRLGSPSS-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NZC7-1", "uniprot_id": "WWOX_HUMAN", "id": "Q9NZC7-1", "name": "WW domain-containing oxidoreductase", "aln": "MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQ-VFFVDHINKRTTYLDPRLAFTVDD-NPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHKAK---------------VEAMTLDLALLRSVQHFAEAFKAKNVP-------------LHVLVCNAATFALP-WSLTKDGLETTFQVN---HLGHFYLVQLLQDVLCRSAP----ARVIVVSSESHRFTDINDSLGKLDFSRLSPT------KNDYWAMLAYNRSKLC---NILFSNELHRRLSPRG--VTSNAVHPGNMMYSNIHRSWWVYT---------LLFTLAR--------------------------------PFTKS---------------------------------------MQQGAATTVYCAAVPELEGLG----------------------------------GMYF-NNCCRCMPSPEAQSEE-----------TARTLWALSERLIQERLGSQSG-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803A8-1", "uniprot_id": "WWOX_DANRE", "id": "Q803A8-1", "name": "WW domain-containing oxidoreductase", "aln": "MAALKYAGMEDTDSEDELPPGWEERSTKDGWVYYANHEEMKTQWEHPKTGKKKRCAGALPYGWEQETDDKGQ-IFYVDHINKRKTYFDPRQAFTVED-MQVKP---KRYDGNTGALEILHGQDLSDKVIIVTGANSGIGFETARSFALHGAHVILACRNQSRASKAASLIMGEWSKAR---------------VEVLPLDLASLRSVRQFAELFKATKLP-------------LHVLVCNAAVCSQP-WRLTEDGFESTFQIC---HLGHFLLVQLLQDVLRLSAP----ARVVVVSSESHRFTDLLDSCGNLDLDLLSPP------QKNYWSLLAYNRAKLC---NLLFSSELHRRMSPHG--ICCNALHPGSMMFTSIHRSWWLLT---------LLFSLAR--------------------------------PFTKS---------------------------------------MQQGAATTVYCAVAPELEGIG----------------------------------GMYF-NNCFRCLPSPQAQDPA-----------AALSLWELSERLVQERSTPPQVL----------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLU5-1", "uniprot_id": "WWOX_DROME", "id": "Q9VLU5-1", "name": "WW domain-containing oxidoreductase", "aln": "MIALP-----DTDSEDELPPGWEERATDDGTVCYVNQQGKTSQWTHPRTGRSKRITGELPLGWEKYYDEQGKRFMFLNKETQQRTNVDPRLAFAVEEPTQNVAQVRQRFDSCSTALQVLHGKDLHGRTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARS-------------RCRFAALDLSSLRSVQRFVEEIKQSVSH-------------IDYLILNAGVFALP-YTRTVDGLETTFQVS---HLSHFYLTLQLETLFDYKT------RIIVLSSESHRFANLP--VENLAVHHLSPP------PEKYWSMMAYNNAKLC---NVLFAQELAQRWKQRG--ISVFSLHPGNMVSSDLSRNYWFYR---------LLFAIVR--------------------------------PFTKS---------------------------------------LQQAAATSIYCATANELTGLS----------------------------------GLYF-NNCFFCEPSKLSKSAA-----------LQQQLWKLSENLIAELVEQEQH-----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08651-1", "uniprot_id": "ENV9_YEAST", "id": "Q08651-1", "name": "Probable oxidoreductase ENV9", "aln": "--------------------------------------------------------------------------------------MLDPRILPYYDPAVERKIAVVTGGNTGIGWYTVLHLYLHGFVVYICGRNS---HKISKAIQEILAEAKKRCHEDDDGSSPGAGPGPSIQRLG--------------SLHYIHLDLTDLKCVERAALKILKLEDH-------------IDVLVNNAGIMAVP-LEMTKDGFEVQLQTN---YISHFIFTMRLLPLLRHCRG-----RIISLSSIGHHL--------EFMYWKLSKT--WDYKPNMLFTWFRYAMSKTA---LIQCTKMLAIKYPDVL----CLSVHPGLVMNTNLFSYWTRLPIVG--IFFWLLFQVVG--------------------------------FFFG----------------------VSN----------------EQGSLASLKCALDPNLSVEKDN--------------------------------GKYFTTGGKESKSSYVSNNVD-----------EAASTWIWTVHQLRDRGFDI-------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A8M1RH38-1", "uniprot_id": "A0A8M1RH38_DANRE", "id": "A0A8M1RH38-1", "name": "", "aln": "--------------------------------------------------------------------------------------MSLYRNILWFIKGMREYTRSGFENASKSFAAKDLDVSMVGRSFMITGANSGIGKATAMTIAKKGGTVHIVCRNKEKAERAREEIVSASGNTM---------------VFVHVLDLSESRKVWEFAEAFKKEHTS-------------LNVLINNAGCMVNQ-REINSDGLEKNFATN---TLGVYILTKCLIPLLEKSRD----PRVITVSSGGMLV-------QKLNPDDLQTER------AQFDATMVYAQNKRQ---QVVMTEFWAKAYPKIH----FSVMHPGWADTPAVASAMPQFY--------QLMRDRLR---------------------------------------------------------------------------SAEQSSDTLIWLAMSRVTITFP---------------------------------SGLFFQDRQPVSVHLPLAWTHSPR---------KEVKAFMRCLETLAISVKHSEGDNI--------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B707-1", "uniprot_id": "A0ACD6B707_DANRE", "id": "A0ACD6B707-1", "name": "", "aln": "-----------------------------------------------------MLLGYMAVFGRLWAGCPHGKITFCTFAGLVLALCLGVSGSQTLPDVHWPHCRFMDEKVHVNKEGHIETEYIQRKAVVQFGKDGDSALHPAITFLVTGSEVDMRHYLEGSENMIQCEIRRYSTGGIVMRWPVAGAQEYDVWFTCTLRHTQGLFVITTFLRHTPATPAQGKLDFLQWMKISDGDLLTTSAAMVILTRTPSVEVGFSKEPELHCQFAVDHKLPKATVEWKLQRHGK---HIKLFSYSSLTGKTEGSGVTVKAIEGGNASLKLQPVRKRSEGTYVCSVKIPPLNGSHNIPFSISEQPRVSLNVPNTLAMAAGQDKKVICDAESYYPLDVN------IEWYLERHRENP---------------------------MPSFLNVR--------------------HSSHRLN-----------QDGTYSISAFLYLEPGLENSG----------------------------------YQYTCSVSHKSLLNPINKSFFLVVT------ETDSTMWYFAVFGFIISMLLIMHYIPRIFAGRKSAKRYMSSCLGV-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . : . * .*. . : : ::. . : . ", "identical_positions": 3, "similar_positions": 15, "identity": "0.46%" }, { "cls_id": "homologset.agr.SGD:S000005775", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1L1K3-1", "uniprot_id": "APC5_RAT", "id": "A1L1K3-1", "name": "Anaphase-promoting complex subunit 5", "aln": "-------------MMTNGVVHANLFGIKDWVTP--------------YKIAVLVLLNEMGR------TGEGAVSLVERRKLNQLLLPLLQGPDITLSKLYKLIEESCPQLAN----SVQIRIKLMAEGELKDLEQFFDDL-SDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNG------EKKTVEDADMD---REDGER-QMEKEELDV-SVREEEVSCS----GPLSQ---KQAEFFLSQQAALLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSS-THSLLHYFDRL-ILTGAEGKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKR-ADSYVLLEHSVKKAVHFGLP-------------RAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLESLSAGVQQNNTESFAVALCHLAELHAEQGCFAAAGEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKFHLADSLVTGITALNGIEGVYRKAVVLQAQNQMTEAHKLLQKLLTYCQKLKNTEMVISVLLSVAELYWRSSSPTIAMPVLLEALALSKEYRLQYLASETVLNLAYAQLILGIPEQALTLLHMAIEPILADGAILDKGRAMFLVSKCQVASAASYDPVKKAEALEAAIQNLTEAKNYFAKVDCRERIRDVSYFQARLYHALGKTQERNHCAMVFRQLHQELPSHGVPLINHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BTZ4-1", "uniprot_id": "APC5_MOUSE", "id": "Q8BTZ4-1", "name": "Anaphase-promoting complex subunit 5", "aln": "-------------MMTNGVVHANLFGIKDWVTP--------------YKIAVLVLLNEMGR------TGEGAVSLVERRKLNQLLLPLLQGPDITLSKLYKLIEESCPQLAN----SVQIRIKLMAEGELKDMEQFFDDL-SDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNG------EKKTVEDADMD---REDGEK-QMEKEELDV-SVREEEVSCS----GPLSQ---KQAEFFLSQQAALLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSS-THSLLHYFDRL-ILTGAEGKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKR-ADSYVLLEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLESLNAGVQQNNTESFAVALCHLAELHAEQGCFAAAGEVLKHLKDRFPPNSQHAQLWMLCDQKIQFDRAMNDGKFHLADSLVTGITALNGIEGVYRKAVVLQAQNQMTEAHKLLQKLLTYCQKLKNTEMVISVLLSVAELYWRSSSPTIAMPVLLEALALSKEYRLQYLASETVLNLAYAQLILGIPEQALTLLHMAIEPILADGAVLDKGRAMFLVSKCQVASAASYDPVKKAEALEAAIQNLSEAKNYFAQVDCRERIRDVAYFQARLYHALGKTQERNHCAMIFRQLHQELPAHGVPLINHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJX4-1", "uniprot_id": "APC5_HUMAN", "id": "Q9UJX4-1", "name": "Anaphase-promoting complex subunit 5", "aln": "-MASVHESLYFNPMMTNGVVHANVFGIKDWVTP--------------YKIAVLVLLNEMSR------TGEGAVSLMERRRLNQLLLPLLQGPDITLSKLYKLIEESCPQLAN----SVQIRIKLMAEGELKDMEQFFDDL-SDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNG------EKKTVEDADMELTSRDEGER-KMEKEELDV-SVREEEVSCS----GPLSQ---KQAEFFLSQQASLLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSS-THSLLHYFDRL-ILTGAESKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKR-SDSYVLLEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQGCFAAASEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNSIEGVYRKAVVLQAQNQMSEAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIALPMLLQALALSKEYRLQYLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILDKGRAMFLVAKCQVASAASYDQPKKAEALEAAIENLNEAKNYFAKVDCKERIRDVVYFQARLYHTLGKTQERNRCAMLFRQLHQELPSHGVPLINHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PFK7-1", "uniprot_id": "A0A8M1PFK7_DANRE", "id": "A0A8M1PFK7-1", "name": "Anaphase-promoting complex subunit 5", "aln": "-MASVHESLYFNPMMTNGVVHANIFGIKDWVTP--------------YKIAVLALLYEMST------TKP--MALLDRRRLNKLILPLQQGPDLTLEQFLKIVEECCLRMVN----AVKLRLFLMADGELQDMEHFFTIL-PSAFSDSEP--FKTSVVGLFMRQMLLAYNKLSFSQVYKLYKSLQQFCHRGN---QPELSALPAEDMELTSNEDPSADHIDKDELDTPSLHQSELSRSEESQGPLSQ---KQAEYFLARQAYLLKNDENKAMSPAKLQDELNNILKFNPDFAEAHYLSYLNSLRVQDIYIS-THSLLHYFDRL-ILSGAEGKSNGDEGYGRSLRYAVLNLATLHCRFGHYHQADLALQEAIRIAQEANDHVCLQHCLSWLYTLEQMRGSDSVVLTEDSVKIAAHFCLPYLASLGIQSLVQQGAKQGMPANKLLDALRGTDIMHWKQSLSELIEISLAQTTSIWRMYGKSTMAQQQAQLLLNMNSLEPVNFSVQQNNTEAFAVALCHLAELHAEQGLYPVVTDIMKHLKQQFPPHTQHAKLWMLCDLKIQFEKAMNDGKYHLAEPHVTAITALNSTEGMYRKAQLLKALNQTTEASKILQQLQQQCEKSKNTQMSIRVMLASAELHWDSSGFATALPLLLQALALSRQHNLQSLTSETLLHLAFTQLMLGISEQALGLVQDVLESVLAHGSLMDKGRALLLAARCQMASAGAAAQEHRLSAVELAVHTLDEAAVYFSRLDCKERMRDIYYLQARLHQTLGNISQRNRCAMLFRLLDQELPSSRMTVVNRL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZL2-1", "uniprot_id": "Q9VZL2_DROME", "id": "Q9VZL2-1", "name": "Anaphase-promoting complex subunit 5", "aln": "MILCLHFAGKSKIGFRGPKLTMNLFEELDTLDPSFKLEPPRIETPTAHKITVLILLKQYVINKKNCLDTGISMRTQRRRMFYMLVFKLIQEQDKSYNELHSLLTTGKYKLDTLMLESFEKAMSEFCAGSIEALFDFSEIQNIDEILNENYGISQFSMVGVYVRRVGVVLERLSFPEMMDMYKNVCSYYERGVRAAASGSRMAVAGGILHREETPPPNPITEKPEDPKPKKKVEAVARIAQERNPLSKWAPKQAKFFINKQSELLENNERKALPPLELQKKVQEIIHDLPLTTTPYFLGYMNQLRVRDYYNA-LSALHRALDRS-PVR----LMSQEKGY----QYFCVNLAVLHATFGHRDEALAALRESIMLAQEHGDKRSLNLANTWYCLLRDEL-PLSAVQKSVQDANEVDGSLLQNYTLALHFAVKLGTVAGYQPLRLFDLLQHSDNLTNRNNFADHASEALALRSAVWSAYGRHELAALYSQVLLTGR-------DRFGSGSAGLGSALASFALWLQLQGEPQLSKVLLHHAKQRFP-RLPSAEGWMISQCHVVIQAGIYQCRWHDALKACDQLYLIDPSDSLFQRASIYVAKREFFNARRLLDKLAVQDNIPFLLRMRVQVLLGYCGMANGRFSSETTMLLLRVSEEMS-EAQMDYELALVDLLLALQLLLLGMPQKAYQAIKRCMHDIHINGGLYERAKTDFVFVRCLLAVNQNDAEKRKAQLLKSQVI-LQRAAQSFKKLSAHAKVLDVYVFLAQRFNEFGDRNLRNKYAGEFRRYFTDHPIPREYLGSP-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08683-1", "uniprot_id": "APC5_YEAST", "id": "Q08683-1", "name": "Anaphase-promoting complex subunit 5", "aln": "------------------MSKYGPLGITNFITP--------------YDLCILILIHAHCS------------QDNGISVPTAVFLRLISPTRPSLEWNPLLKDNSNLRSSS-----------IVPPPVLPILDNIIRILLDDKDG---------NKIALTLMGYLEAIN--GLDSINRLMMDLEKNCLVN----------------------NYRSMKMRTTSTRRQMTRASFLGT-------------FLSTCIRKYQIGDFEMRETIWINLQNFKTVFKHTPLWLRFKDNVHIQKVKNCLLANDEISVEDQQMVEFFQHFNNGNDADSKTMNEENYG-----TLISIQHLQSIVNRQIVNWLDNTEFNLMGQEETSSTYEEQSGLVFDLLDTLSLNDATKFPLIFILKYLEAIKENSYQTALDSLHNYFDYKSTGNSQNYFHISLLSLATFHSSFNECDAAINSFEEATRIARENKDMETLNLIMIWIIN-----FIEVHPEYANRFYITVEQIIKYLKNSS--DVEDANIFSNAYKFETLLSMVKESKTAEVSSSLLKFMAITLQNVPSQNFDLFQSLVSYEVKFWKELGYESISDVYEK-FLSKTSSSSLRNYDSSIINQDIKVAFKALEEDDFLKVKQYLLKSESLELDYDQKINLKYLRVKYLVKIGDYDLSMRLINQYVKECCEEVADSNWRFKFEIESINVLLLSDVGIRSLPKIIKLIDEYKEIGNPLRCVILLLKLCEVLIQVGKSMEAECLISCNLSTILEFPFVRKKTDELLESLSVEEDRDVQMT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : * :.: :* *: :.: * . : . : : . . : : .: . . :.: : . . .: .: : : . . . . : . :. : : * :: * : .:: .:. : * * ..* : . ::: ::.* :.: *:. ..: * :.** . : . * : . . : : . : .: : : : . : :: . . : : :: : .. : :* .: .: : : : . : : : : : : : : : . . : : :. : : : :. : .:: . : *.: . . . . . .: : . :. : . : * . : . :: . . :. . . . ", "identical_positions": 18, "similar_positions": 169, "identity": "2.25%" }, { "cls_id": "homologset.agr.SGD:S000005776", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PQL4-1", "uniprot_id": "CLP1_RAT", "id": "Q5PQL4-1", "name": "Polyribonucleotide 5'-hydroxyl-kinase Clp1", "aln": "------MSEESNDD------------KKPTTKFELERETELRFEVEAS-QSVQLELLAGMAEIFGTELTRNKKFTFDAGAKVAVFTWHGCSLQLSG---RTEVAYVSKDTPMLLYLNTHTALEQMRRQAEKEEERGPRVMVVGPTDVGKSTVCRLLLNYAVRLGR-RPTYVELDVGQGSVSIPGTMGALYIERPADVEEG------------FSIQAPLVYHFGSTTPGTNIKLYNKITSRLADVFNQRCEVNRRASVSGCVINTCGWVKGYG-YQALVHAASAFEVDVVVVLDQER--LYNELKRDLPHFVR---TVLLPKSGGVVERSKDFRRECRDERIREYFYGFRG-CFYPHAFNVKFSDVKIYKVGAPTIPDSCLPLGMSQEDNQLKLVPVTPGRD-MVHHLLSVSTAEGTEEN-----LSETSVAGFIVVTSVDVEHQVFTVLSPAPRPLPKNFLLIM-DIRFMDLK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LI9-1", "uniprot_id": "CLP1_MOUSE", "id": "Q99LI9-1", "name": "Polyribonucleotide 5'-hydroxyl-kinase Clp1", "aln": "------MSEESNDD------------KKPTTKFELERETELRFEVEAS-QSVQLELLAGMAEIFGTELTRNKKFTFDAGAKVAVFTWHGCSLQLSG---RTEVAYVSKDTPMLLYLNTHTALEQMRRQAEKEEERGPRVMVVGPTDVGKSTVCRLLLNYAVRLGR-RPTYVELDVGQGSVSIPGTMGALYIERPADVEEG------------FSIQAPLVYHFGSTTPGTNIKLYNKITSRLADVFNQRCEVNRRASVSGCVINTCGWVKGYG-YQALVHAASAFEVDVVVVLDQER--LYNELKRDLPHFVR---TVLLPKSGGVVERSKDFRRECRDERIREYFYGFRG-CFYPHAFNVKFSDVKIYKVGAPTIPDSCLPLGMSQEDNQLKLVPVTPGRD-MVHHLLSVSTAEGTEEN-----LSETSVAGFIVVTSVDVEHQVFTVLSPAPRPLPKNFLLIM-DIRFMDLK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92989-1", "uniprot_id": "CLP1_HUMAN", "id": "Q92989-1", "name": "Polyribonucleotide 5'-hydroxyl-kinase Clp1", "aln": "------MGEEANDD------------KKPTTKFELERETELRFEVEAS-QSVQLELLTGMAEIFGTELTRNKKFTFDAGAKVAVFTWHGCSVQLSG---RTEVAYVSKDTPMLLYLNTHTALEQMRRQAEKEEERGPRVMVVGPTDVGKSTVCRLLLNYAVRLGR-RPTYVELDVGQGSVSIPGTMGALYIERPADVEEG------------FSIQAPLVYHFGSTTPGTNIKLYNKITSRLADVFNQRCEVNRRASVSGCVINTCGWVKGSG-YQALVHAASAFEVDVVVVLDQER--LYNELKRDLPHFVR---TVLLPKSGGVVERSKDFRRECRDERIREYFYGFRG-CFYPHAFNVKFSDVKIYKVGAPTIPDSCLPLGMSQEDNQLKLVPVTPGRD-MVHHLLSVSTAEGTEEN-----LSETSVAGFIVVTSVDLEHQVFTVLSPAPRPLPKNFLLIM-DIRFMDLK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F3I6-1", "uniprot_id": "CLP1_DANRE", "id": "E7F3I6-1", "name": "Polyribonucleotide 5'-hydroxyl-kinase Clp1", "aln": "------MTAEAAEKSVEEGLSSSGSAGSSGTRFDLDKETELRFEVEAG-ERVQLELLSGLAEIFGSELNRNKKYTFGPGSKIAVFTWQGCGVALSG---KTEVAYVSKDTPMLLYLNTHAALEQMRRQAEKDNERGPRVMVVGPTDVGKSTVCRMLLNYAVRLGR-RPTLVELDVGQSSVSVPGTMSALCIERPADVEEG------------FSVQAPLVFHFGSTTPGTNIKLYNKLTSSLADAFSQRCEVNRRASVGGCIINTCGWVKGSG-YQALVHCASAFQVDVVLVLDQER--LYNELKRDLPHFVR---VVLLPKSGGVVERSKDCRRETRDEKIREYFYGFRGTSFYPHAFDVRFSDVRIYKIGAPSIPDSCLPLGMSQDDTQLKLVPVSPGRD-LTHHVLSVSSVDDEAEVGQSRGILESPACGFIVVTAVDTQAQVMTVLSPAPRPLPRHTLLIM-DIRFIDLK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7K284-1", "uniprot_id": "CLP1_DROME", "id": "Q7K284-1", "name": "Protein CLP1 homolog", "aln": "------MSEDQGKD------------------YTLESDSELRFEIEQKDAKVLVSLVSGFAELFGTELVKKKQYEFGVGAKVAIFTYQGCVLHVSG---KMDVCYISKETPMVQYVNCHAALEQFRMEAEEKDRYGPVAMVVGPMDVGKSTLCRILLNYAVRVGR-RPLYADLDVGQGSIAISGSVATILIERPANVEEG------------FAKTAPLVYHFGHKSPSGNSVLYNAVVSKMAEVTLQSLNSNKRTKSSGIIINTCGWVKGSG-YAHLLHAAKAYGACAIFVLDQER--LYNELLRDVPKGVH---VVLLPKSGGVVERSKELRHEARDQRIKEYFYGNTRAPFYPFSFEVKFQDLRLYKIGAPPLPDSCMPIGMKAEDNKTKVVAVTPTPA-LIHHVLALSFAESVEDD-----VIGTNVAGFCCVTEVDMERQAVMLLSPQPRPLPPNALLLWSELQFMDNHT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08685-1", "uniprot_id": "CLP1_YEAST", "id": "Q08685-1", "name": "mRNA cleavage and polyadenylation factor CLP1", "aln": "MASLPGIDEHTTSEELITG-------DNEWHKLVIPKGSDWQIDLKAE-GKLIVKVNSGIVEIFGTELAVDDEYTFQN-WKFPIYAVEETELLWKCPDLTTNTITVKPNHTMKYIYNLHFMLEKIRMSNFE----GPRVVIVGGSQTGKTSLSRTLCSYALKFNAYQPLYINLDPQQPIFTVPGCISATPISDILDAQLPTWGQSLTSGATLLHNKQPMVKNFGLERINENKDLYLECISQLGQVVGQRLHLDPQVRRSGCIVDTPSISQLDENLAELHHIIEKLNVNIMLVLCSETDPLWEKVKKTFGPELGNNNIFFIPKLDGVSAVDDVYKRSLQRTSIREYFYGSLDTALSPYAIGVDYEDLTIWKPSN----------VFDNEVGRVELFPVTITPSNLQHAIIAITFAERRADQAT---VIKSPILGFALITEVNEKRRKLRVLLPVPGRLPSKAMILT-SYRYLE---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .. : :: ::::: : :.: :*:.*:**:** ..:: * *..::: . : . :. :. : .* * * **::* . : ** .::** :.**:::.* * .**::.. :* :** * .::.* :.: *. :.: : *:* :** . * ** * :.:. * . : :. .* :::* . : * * . . :.** .* *:::: : . : .::** .** .. ::. : *:***** : *.:: * :.*: ::* . :. : : ::..*: : * ::::: .: : : : ** :* *: : : . :* * * ** : ::: . :::: ", "identical_positions": 72, "similar_positions": 156, "identity": "15.16%" }, { "cls_id": "homologset.agr.SGD:S000005777", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24329-1", "uniprot_id": "THTR_RAT", "id": "P24329-1", "name": "Thiosulfate sulfurtransferase", "aln": "MVHQVLYRALVSTKWLAESIRSGKVGPSLRVLDASWYSPGT-RQARKEYQER-HVPGASFFDIEECRDTTSPYEMMLPSEAHFGDYVGNLGISNDTHVVVYDGDDLGSFYAPRVWWMFRVFGHRTVSVLNGG-----FRNWLKEGHPVTSEPSRPEPAVFKATLNRSLLKTYEQVLENLQS----KRFQLVDSRAQGRYLGTQPEPDAVGLDSGHIRGSVNVPFMNFLTED--GFEKSPEELRAIFQDKK------VDLSQPLIATCRKGVTACHIALAAYLCGKPDVAVYDGSWSEWFRRAPPETRVSQGKSGKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52196-1", "uniprot_id": "THTR_MOUSE", "id": "P52196-1", "name": "Thiosulfate sulfurtransferase", "aln": "MVHQVLYRALVSTKWLAESIRSGRLGPSLRVLDASWYSPGT-RQARKEYQER-HVPGASFFDIEECRDTTSPYEMMLPSEAHFGDYVGNLGISNDTHVVVYDGDDLGSFYAPRVWWMFRVFGHRTVSVLNGG-----FRNWLKEGHPVTSEPSRPEPAVFKATLNLSLLKTYEQVLENLQS----KRFQLVDSRAQGRYLGTQPEPDIVGLDSGHIRGSVNMPFMDFLTKD--GFEKSPEELRAIFQDKK------VDLSQPLIATCRKGVTACHVALAAYLCGKPDVAVYDGSWSEWFRRAPPETRVSQGKSGKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16762-1", "uniprot_id": "THTR_HUMAN", "id": "Q16762-1", "name": "Thiosulfate sulfurtransferase", "aln": "MVHQVLYRALVSTKWLAESIRTGKLGPGLRVLDASWYSPGT-REARKEYLER-HVPGASFFDIEECRDTASPYEMMLPSEAGFAEYVGRLGISNHTHVVVYDGEHLGSFYAPRVWWMFRVFGHRTVSVLNGG-----FRNWLKEGHPVTSEPSRPEPAVFKATLDRSLLKTYEQVLENLES----KRFQLVDSRSQGRFLGTEPEPDAVGLDSGHIRGAVNMPFMDFLTED--GFEKGPEELRALFQTKK------VDLSQPLIATCRKGVTACHVALAAYLCGKPDVAVYDGSWSEWFRRAPPESRVSQGKSEKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99J99-1", "uniprot_id": "THTM_MOUSE", "id": "Q99J99-1", "name": "3-mercaptopyruvate sulfurtransferase", "aln": "MAAPQLFRALVSAQWVAEALKAPRSSQPLKLLDASWYLPKLGRDARREFEER-HIPGAAFFDIDRCSDHTSPYDHMLPNATHFADYAGSLGVSAATHVVIYDDSDQGLYSAPRVWWMFRAFGHHSVSLLDGG-----FRHWLNQNLPISSGKSHSEPAEFSAQLDPSFIKTHEDILENLDA----RRFQVVDARAAGRFQGTQPEP-RDGIEPGHIPGSVNIPFTEFLTNE--GLEKSPEEIKRLFKEKK------VDLSKPLVATCGSGVTACHVVLGAFLCGKSDVPVYDGSWVEWYMRAQPEHIISEGRGKTQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P97532-1", "uniprot_id": "THTM_RAT", "id": "P97532-1", "name": "3-mercaptopyruvate sulfurtransferase", "aln": "MAAPQLFRALVSAQWVAEALKSPRASQPLKLLDASWYLPKLGRDARREFEER-HIPGAAFFDIDRCSDHTSPYDHMLPSATHFADYAGSLGVSAATHVVIYDGSDQGLYSAPRVWWMFRAFGHHSVSLLDGG-----FRYWLSQNLPISSGKSPSEPAEFCAQLDPSFIKTHEDILENLDA----RRFQVVDARAAGRFQGTQPEP-RDGIEPGHIPGSVNIPFTEFLTSE--GLEKSPEEIQRLFQEKK------VDLSKPLVATCGSGVTACHVVLGAFLCGKPDVPVYDGSWVEWYMRAQPEHVISQGRGKTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P25325-1", "uniprot_id": "THTM_HUMAN", "id": "P25325-1", "name": "3-mercaptopyruvate sulfurtransferase", "aln": "MASPQLCRALVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEER-HIPGAAFFDIDQCSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLDGG-----LRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLES----RRFQVVDSRATGRFRGTEPEP-RDGIEPGHIPGTVNIPFTDFLSQE--GLEKSPEEIRHLFQEKK------VDLSKPLVATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEWYMRARPEDVISEGRGKTH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08686-1", "uniprot_id": "THTR_YEAST", "id": "Q08686-1", "name": "Sulfurtransferase TUM1", "aln": "----MPLFDLISPKAFVKLVASEKVHR-IVPVDATWYLPSWKLDNKVDFLTKPRIPNSIFFDIDAISDKKSPYPHMFPTKKVFDDAMSNLGVQKDDILVVYDR--VGNFSSPRCAWTLGVMGHPKVYLLNNFNQYREFKYPLDSSKVAAFSPYPKSHYESSESFQDKEIVDYEEMFQLVKSGELAKKFNAFDARSLGRFEGTEPEP-RSDIPSGHIPGTQPLPYGSLLDPETKTYPEAGEAIHATLEKALKDFHCTLDPSKPTICSCGTGVSGVIIKTALELAGVPNVRLYDGSWTEWVLKSGPE-WIAENRD---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*.: ..: : : : : :**:** * : : :: : ::*.: ****: * *** *:* * : . **: :*:** * : :** * : .:** * :*:. :: * .. : :: : :*:: : :.: ::*: .*:*: **: **:*** .: .*** *: :*: .:* : :. * :: :: :* *:* :.:* .**:. : . *.* .:* :***** ** :: ** :::.:. ", "identical_positions": 69, "similar_positions": 96, "identity": "21.84%" }, { "cls_id": "homologset.agr.SGD:S000005778", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L7W5-1", "uniprot_id": "A0ABK0L7W5_RAT", "id": "A0ABK0L7W5-1", "name": "Translation machinery-associated protein 16", "aln": "---MLHEPKGLKAKMVGREKKVIHPYSRKAAQITRESHKQDKKERLKTERALRLNLIGDKLQWFHSHLDTKKSR---YSK-KDACELIERYLDRFSSELEQIELHNSIKDRQGRRHHSREAVIKQTMERERQQYEGYGFEIPDIVDSNALNTFREWDFDLKKLPNIKMRKLCANDAVPKKRKQKNILNIEKDLGELDLTGETGDATDGKLEPASESSDTDEEMTAVPDSPH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CR02-1", "uniprot_id": "TMA16_MOUSE", "id": "Q9CR02-1", "name": "Translation machinery-associated protein 16", "aln": "------MPKGLKGKMVGREKKVIHPYSRKAAQITRESHKQDKKERLKTEKALRLNLIGDKLQWFHSHLDMKKTR---YSK-KDACELVERYLDRFSSELEQIELQNSIKDRQGRRHHSREAVIKQTLERERQQYEGYGFEIPDILDSNTLQTFREWDFDLKKLPNIKMRKLCADDAVPKKRKQKNILNIEKDLGELELSGPTGATTDGKLEPASESSDTDEEMTPVPVSPH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EY4-1", "uniprot_id": "TMA16_HUMAN", "id": "Q96EY4-1", "name": "Translation machinery-associated protein 16", "aln": "------MPKAPKGKSAGREKKVIHPYSRKAAQITREAHKQEKKEKLKNEKALRLNLVGEKLQWFQNHLDPQKKR---YSK-KDACELIERYLNRFSSELEQIELHNSIRDRQGRRHCSRETVIKQTMERERQQFEGYGLEIPDILNASNLKTFREWDFDLKKLPNIKMRKICANDAIPKTCKRKTIITVDQDLGELELN--------------DESSDSDEEMTAVA----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A7MCB7-1", "uniprot_id": "TMA16_DANRE", "id": "A7MCB7-1", "name": "Translation machinery-associated protein 16", "aln": "------MPKGRKPKGP-VEKKVIHPYSRKAAYLARDAIKQERKEKLKGEKAQRLNLVGEKLLWFQNQLNPDKPE---YTR-QDACEITERYLQRFDGELEQIELANSIKGRQGRQHSSREAIIKQTIERERAQYEGNGFEIPDIINAKHLKIFREWNGDLKKLPCIKMRKLSAKGSDSKPSTVSQDTHMEEENEE------------------DKSLDSDSDL--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXY4-1", "uniprot_id": "TMA16_DROME", "id": "Q9VXY4-1", "name": "Translation machinery-associated protein 16 homolog", "aln": "-----------MTNLRKELEKCKHPNSRKTKALGKKARRQNNKHKVRLGHAIKSNITGEKLSWFLGQIDEGRTE---PLRPQELEDLIELYFTRFDEELEQINLKQSIGKHRANQHAARKDVITMTLEKERNEFRTGGLELMNLCDPLKLKMLRDWDGSALSVQHLKLDLVSYN-MLQRLKEQSKKKETSEQMET------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08687-1", "uniprot_id": "TMA16_YEAST", "id": "Q08687-1", "name": "Translation machinery-associated protein 16", "aln": "MPVTKSLSKLQKNLSKKGKNITVHPKGRKYEKLVRATMREDKIAAKKKLHQDKRVHELARVKFMQDVVNSDTFKGQPIFDHAHTREFIQSFIERDDTELDELKKK----RRSNRPPSNRQVLLQQRRDQELKEFK-AGFLCPDLSDAKNMEFLRNWNGTFGLLNTLRLIRINDKGEQVVGGNE------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** .** : : : :::. : : : :: :: . :: . . :: : :: * . **:::: : . *: :: ::* ::. *: :: :. :: :*:*: : ::: : . ", "identical_positions": 12, "similar_positions": 57, "identity": "5.19%" }, { "cls_id": "homologset.agr.SGD:S000005779", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9GZZ1-1", "uniprot_id": "NAA50_HUMAN", "id": "Q9GZZ1-1", "name": "N-alpha-acetyltransferase 50", "aln": "MKGSRIELGDVTPHNIKQLKRLNQVIFPVSYNDKFYKDVLEVG---------------ELAKLAYFNDIAVGAVCCRVDHSQNQ----KRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYRKFGFEII-ETKKNYYKRIEP--ADAHVLQKNLK--VPSGQNA-DVQKTDN------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PGB6-1", "uniprot_id": "NAA50_MOUSE", "id": "Q6PGB6-1", "name": "N-alpha-acetyltransferase 50", "aln": "MKGSRIELGDVTPHNIKQLKRLNQVIFPVSYNDKFYKDVLEVG---------------ELAKLAYFNDIAVGAVCCRVDHSQNQ----KRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYRKFGFEII-ETKKNYYKRIEP--ADAHVLQKNLK--VPSGQNA-ETQKTDN------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A5Y6-1", "uniprot_id": "D4A5Y6_RAT", "id": "D4A5Y6-1", "name": "N-alpha-acetyltransferase 50", "aln": "MKG-RIELGDVTPHNIKQLKRLNQVIFPVSYNDKFYKDVLEVG---------------ELAKLAYFNDIAVGAVCCRVDHSQNQ----KRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYRKFGFEII-ETKKNYYKRIEP--ADAHVLQKSLR--VPSGQSA-ETQKTDN------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DBY2-1", "uniprot_id": "NAA50_DANRE", "id": "Q6DBY2-1", "name": "N-alpha-acetyltransferase 50", "aln": "MKG-RIELGDVTPHNIKQLKRLNQVIFPVSYNDKFYKDVLEVG---------------ELAKLAYFNDIAVGAVCCRVDHSQNQ----KRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYQKFGFEII-ETKKNYYKRIEP--ADAHVLQKSLR--SPCAPPAGELQKAD-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NHD5-1", "uniprot_id": "SAN_DROME", "id": "Q9NHD5-1", "name": "Probable N-acetyltransferase san", "aln": "MTRSSIELGDVTPHNIKQLKKLNTVVFPVSYNDKFYVDVLEAG---------------ELAKLAYYNDIVVGAVCCRIDNTENQ----RRLYIMTLGCLSPYRRLGIGTVMFEHIMNFAEKDGNFDSIFLHVQINNNGAIEFYKKFGFEIV-DTKEQYYKRIEP--ADAHVLQKTLRRTAPNSNSTATSTTANSNSRSKARQFTFV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08689-1", "uniprot_id": "NAT5_YEAST", "id": "Q08689-1", "name": "N-alpha-acetyltransferase NAT5", "aln": "MGRDICTLDNVYANNLGMLTKLAHVTVPNLYQDAFFSALFAEDSLVAKNKKPSSKKDVHFTQMAYYSEIPVGGLVAKLVPKKQNELSLKGIQIEFLGVLPNYRHKSIGSKLLKFAEDKCS-ECHQHNVFVYLPAVDDLTKQWFIAHGFEQVGETVNNFIKGVNGDEQDAILLKKHIS-----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *.:* .:*: *.:* * .* *:* *: :: . .::::**:.:* **.: .:: .::: : : * ** *. **: .**: :::. : .. : ..::::: :: : ::: .*** : :* ::: * :: ** :*:* : ", "identical_positions": 33, "similar_positions": 68, "identity": "16.02%" }, { "cls_id": "homologset.agr.SGD:S000005780", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZYJ9-1", "uniprot_id": "A0A8I5ZYJ9_RAT", "id": "A0A8I5ZYJ9-1", "name": "Translocation protein SEC63 homolog", "aln": "MAGQQFQYDDSGNTFFYFLTSFVGLIVIPATYYLWP----------------RDQNAEQIRLKNIRKVYGRCMWYRLRLLKPQPN--IIPTVKKIVLLAGWALFLFLAYKVSKT----DREYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDK-GGDEV---------MFMRIAKAYAALTDEESRKNWEEFGNPDGPQATSFGIALPAWIVDQKNSILVLLVYGLAFMVILPVVVGSWWYRSIRYSGDQILIRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDPQYNKDATSRPTDNVLIPQLIREIGSINLKKNEPPLTCPYSLKARVLLLSHLARMKI-PETLEEDQQFMLKKCPALLQEMVNVICQLIIMARSREEREFRAPTLASLENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKFKIKSIQDLVSLKEADRHSLLHFLEDEKYEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITVGSLVTVLVKLTRQTMAEVFEKEQSICAAEEQPAEDGQSDANKNKAKGGWQQKNKGPKKMPKSKKKKPLKKKPTTVPLPQGKQQKQKQANGVVGSEAAMKEEEEDISDKGSDSEEEETNRDS---QSEKDDGSDRDSDREQDEKQSKDDEAEWQELQQSIQRKERALLETKSKITHPVYSLYFPEEKQEWWWLYIADKKEQTLISMPYHVCTLKDTEEVELKFPAPGRPGNHQYTVFLRSDSYMGLDQTKPLKLEVHEAKPVPENHPQWDTAIEGDEDQEDSEGFEDSFEEEEEEEEGGD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VHE0-1", "uniprot_id": "SEC63_MOUSE", "id": "Q8VHE0-1", "name": "Translocation protein SEC63 homolog", "aln": "MAGQQFQYDDSGNTFFYFLTSFVGLIVIPATYYLWP----------------RDQNAEQIRLKNIRKVYGRCMWYRLRLLKPQPN--IIPTVKKIVLLAGWALFLFLAYKVSKT----DREYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDK-GGDEV---------MFMRIAKAYAALTDEESRKNWEEFGNPDGPQATSFGIALPAWIVDQKNSILVLLVYGLAFMVILPVVVGSWWYRSIRYSGDQILIRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDPQYNKDSTSRPTDNILIPQLIREIGSINLKKNEPPLTCPYSLKARVLLLSHLARMKI-PETLEEDQQFMLKKCPALLQEMVNVICQLIIMARSREEREFRAPTLASLENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKYKIKTIQDLVSLKESDRHSLLHFLEDEKYEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITVGSLVTVLVKLTRQTMAEVFEKEQSICAAEEQPTEDGQSDANKIKAKGGWQQKNKGPKKMPKSKKKKPLKKKPTTVPLPQAKQQKQKQANGVVGSEAAIKEEEDDISDKGSDSEEEETNRDS---QSEKEDGSDRESDREQDEKQSKDDEAEWQELQQSIQRKERALLETKSKITHPVYSLYFPEEKQEWWWLYIADRKEQTLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRSDSYMGLDQIKPLKLEVHEAKPVPENHPQWDTAIEGDEDQEDSEGFEDSFEEEEEEEEGGD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGP8-1", "uniprot_id": "SEC63_HUMAN", "id": "Q9UGP8-1", "name": "Translocation protein SEC63 homolog", "aln": "MAGQQFQYDDSGNTFFYFLTSFVGLIVIPATYYLWP----------------RDQNAEQIRLKNIRKVYGRCMWYRLRLLKPQPN--IIPTVKKIVLLAGWALFLFLAYKVSKT----DREYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDK-GGDEV---------MFMRIAKAYAALTDEESRKNWEEFGNPDGPQATSFGIALPAWIVDQKNSILVLLVYGLAFMVILPVVVGSWWYRSIRYSGDQILIRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDPQYNKDATSRPTDNILIPQLIREIGSINLKKNEPPLTCPYSLKARVLLLSHLARMKI-PETLEEDQQFMLKKCPALLQEMVNVICQLIVMARNREEREFRAPTLASLENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKYKIKTIQDLVSLKESDRHTLLHFLEDEKYEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITVGSLVTVLVKLTRQTMAEVFEKEQSICAAEEQPAEDGQGETNKNRTKGGWQQKSKGPKKTAKSKKKKPLKKKPTPVLLPQSKQQKQKQANGVVGNEAAVKEDEEEVSDKGSDSEEEETNRDS---QSEKDDGSDRDSDREQDEKQNKDDEAEWQELQQSIQRKERALLETKSKITHPVYSLYFPEEKQEWWWLYIADRKEQTLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRSDSYMGLDQIKPLKLEVHEAKPVPENHPQWDTAIEGDEDQEDSEGFEDSFEEEEEEEEDDD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VS57-1", "uniprot_id": "Q9VS57_DROME", "id": "Q9VS57-1", "name": "", "aln": "MAGQKFQYDESGGTFYYFVLSFLALILIPTTIYYWP----------------RKKKQDNSKLKEECQCAD-CQKKKTILANAEPYRALTSWTIKLTIVLGWALLLFLTYRVSQF----DYEMASFDPFEILNVPPTSSQAEIKKAYYRLSKVLHPDKETGDEK---------SFMMLSKAYQALTDDVAKENYEKYGNPDGPGAMSFGIALPSWIVEKENSVWVLGLYGLVFMVAMPSAVGVWWYRSIRFSGDKVLLDTTQMYFYFIHKTPHMLLKRALMVLAASLEFDKRHNSQVQERQSDNDEVPALIRQLPNLNEKCKEHPLCRMYSIKARAILHAHLSRMPLNPETLERDRQFVVKKCPYLVQEMVSCVHQLVMMAYAR--RVPRLPSIETIENCMKMSPMIIQGLWEFKSPLLQLPHLTEDHLYFMN--KKRHVKNLQQFAQLKPEESRQLLKNLSDFEYENTMKVLGKMPLIDFSIRCEVIDDENTNVVTAGAIVTVTVTLERKDMKTLFGDTK---APEKQGIKD---ETNEEAAGDEDEAAAAAPVKKASAWAKPRKGGKGKGGKKPAQNQKNQKKVPAKAATTATITASEDQAAAGNSDAESEAGNADGSDVESAAGSGSEDEEKGKNNSSLDDDDDEEWERLQAKLNKRER--LEGKSRLSHTVHCPYFPEEKQEYWWTYICDRKSRTLLTAPYHVTNLVEKEEIQLKFTAPRWPGVYTFTVCLRSDSYLGMDQQQELKLDVQKAPAPPTDHPQWDLSESEPEHTDQQENLSDYTTDTSDEEDGE--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14906-1", "uniprot_id": "SEC63_YEAST", "id": "P14906-1", "name": "Protein translocation protein SEC63", "aln": "-MPTNYEYDEASETWPSFILTGLLMVVGPMTLLQIYQIFFGANAEDGNSGKSKEFNEEVFKNLNEEYTSDEIKQFRRKFDKNSNKKSKIWSRRNIIIIVGWILVAILLQRINSNDAIKDAATKLFDPYEILGISTSASDRDIKSAYRKLSVKFHPDKLAKGLTPDEKSVMEETYVQITKAYESLTDELVRQNYLKYGHPDGPQSTSHGIALPRFLVDGSASPLLVVCYVALLGLILPYFVSRWWARTQSYTKKGIHNVTASNFVSNLVN----------------------------YKPSEIVTTDLILHWLSFAHEFKQFFPDLQPTDFEK--LLQDHINRRDS--GKLNNAKFRIVAKCHSLLHGLLDIACGFRNLDIALG----AINTFKCIVQAVPLTPN---------CQILQLPNVDKEHFITKTG----DIHTLGKLFTLEDAKIGEVLGIKDQAKLNETLRVASHIPNLKIIKADFLVPGENQVTPSSTPYISLKVLVRSAKQPLIP--------TSLIPEENLTEPQDFESQRDPFAMMSKQPLVPYSFAPFFPTKRRGSWCCLVSSQKDGKILQTPIIIEKLSYKNLND-------------------------DKDFFDKRIKMDLTKHEKFDINDWEIGTIKIPLGQP-----------------APETVGDFFFRVIVKSTD-----------YFTTDLDITMNMKVRDSPAVEQVEVYSEEDDEYSTDD-----------------------DETESDDESDASDYTDIDTDTEAEDDESPE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::**::. *: *: : : ::: * * :. : : : : . : : : . :: :: ** *. :* ::.. * ::*:*:*.: . :: :**. * ** **** . :: ::*** :***: ::*: ::*:**** : *.***** ::*: . * :: * : : :* *. ** *: :: . : *:. : : : : :: ::: : : : * .:: :* *: * .*:. : :: ** *:: ::. : : :: : :.: :: . :****:: :::: . .::.: .: *: . :* .: : ::.: * . :* : : :: .*: : . ::: * : : .. :: : . * . : . ::. : : . :: .. . : . .. * :*: .: : ** :::: * . .. : :: ::: . *. * ..*. . *: :. .: .. * : . *:: ", "identical_positions": 80, "similar_positions": 215, "identity": "10.04%" }, { "cls_id": "homologset.agr.SGD:S000005782", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62351-1", "uniprot_id": "TFR1_MOUSE", "id": "Q62351-1", "name": "Transferrin receptor protein 1", "aln": "-------MMDQARSAFSNLFGGEPLSYTRFSLARQVDGDN-SHVEMKLAADEE----------------ENADNNMKASVRKPKRFNGRLCFAAIALVI---FFLIG--FMSGYLGYCKRVEQKEECVKLAETEETDKSETM-------ETEDVPTSSRLYWADLKTLLSEKLNSIEFADTIKQLSQNTYTPREAGSQKDESLAYYIENQFH--EFKFSKVWRDEHYVKIQVKSSIGQNMVTIVQSNGNLD---PVESPE------------GYVAFSKPTEVSGKLVHANFGTKKDFEELSYS----VNGSLVIVRAGEITFAEKVANAQSFNAIGVLIYMDKNKF------PVVEADLALFG----------HAHLGTGDPYTPGFPSFN-HTQFPPSQSSGLPNIPVQTISRAAAEKLFGKMEG-SCPARWN-IDSSCKLELS----------QNQNVKLIVKNVLKERRILNIFGVIKGYEEPDRYVVVGAQRDALGAGVAAKSSVGTGLLLKLAQVFSDMISKDGFRPSRSIIFASWTAGDFGAVGATEWLEGYLSSLHLKAFTYINLDKV--VLGTSNFKVSASPLLYTLMGKIMQDVKHP---VDGKSLYR-----DSNWISKVEK------LSFDNAAYPFLAYSGIPAVSFCFCED------ADYPYLGTRLDTYEALTQKVP-QLNQMVRTAAEVAGQLIIKLTHDVELNLDYEMYNSKLLSFMKDLNQFKTDIRDM------GLSLQWLYSARGDYFRATSRLTTDFHNAEKT--NRFVMREINDRIMKVEYHFLSPYVSPRESPFRHIFWGSGSH------TLSALVENLKLRQKNIT-----------AFNETLFRNQLALATWTIQGVANALSGDIWNIDNEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02786-1", "uniprot_id": "TFR1_HUMAN", "id": "P02786-1", "name": "Transferrin receptor protein 1", "aln": "-------MMDQARSAFSNLFGGEPLSYTRFSLARQVDGDN-SHVEMKLAVDEE----------------ENADNNTKANVTKPKRCSGSICYGTIAVIV---FFLIG--FMIGYLGYCKGVEPKTECERLAGTESPVREE---------PGEDFPAARRLYWDDLKRKLSEKLDSTDFTGTIKLLNENSYVPREAGSQKDENLALYVENQFR--EFKLSKVWRDQHFVKIQVKDSA-QNSVIIVDKNGRLVY--LVENPG------------GYVAYSKAATVTGKLVHANFGTKKDFEDLYTP----VNGSIVIVRAGKITFAEKVANAESLNAIGVLIYMDQTKF------PIVNAELSFFG----------HAHLGTGDPYTPGFPSFN-HTQFPPSRSSGLPNIPVQTISRAAAEKLFGNMEG-DCPSDWK-TDSTCRMVTS----------ESKNVKLTVSNVLKEIKILNIFGVIKGFVEPDHYVVVGAQRDAWGPG-AAKSGVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAGDFGSVGATEWLEGYLSSLHLKAFTYINLDKA--VLGTSNFKVSASPLLYTLIEKTMQNVKHP---VTGQFLYQ-----DSNWASKVEK------LTLDNAAFPFLAYSGIPAVSFCFCED------TDYPYLGTTMDTYKELIERIP-ELNKVARAAAEVAGQFVIKLTHDVELNLDYERYNSQLLSFVRDLNQYRADIKEM------GLSLQWLYSARGDFFRATSRLTTDFGNAEKT--DRFVMKKLNDRVMRVEYHFLSPYVSPKESPFRHVFWGSGSH------TLPALLENLKLRKQNNG-----------AFNETLFRNQLALATWTIQGAANALSGDVWDIDNEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JKX3-1", "uniprot_id": "TFR2_MOUSE", "id": "Q9JKX3-1", "name": "Transferrin receptor protein 2", "aln": "--------MEQRWGLLRRVQQWSPRPSQ--TIYRRVEGPQLEHLEEE--DREEGAELPAQFCPMELKGPEHLGSCPGRSIPIPWAAAGRKAAPYLVLIT---LLIFTGAFLLGYVAFRGSCQACGDSVLVVDEDVNPE--------------DSGRT-TLYWSDLQAMFLRFLGEGRMEDTIRLTSLR---ERVAGSARMATLVQDILDKLS--RQKLDHVWTDTHYVGLQFPDPAHANTLHWVDADGSVQEQLPLEDPE------------VYCPYSATGNATGKLVYAHYGRSEDLQDLKAKGVE-LAGSLLLVRVGITSFAQKVAVAQDFGAQGVLIYPDPSDFSQDPHKPGLSSHQAVYG----------HVHLGTGDPYTPGFPSFN-QTQFPPVESSGLPSIPAQPISADIADQLLRKLTGPVAPQEWKGHLSGSPYRLG----------PGPDLRLVVNNHRVSTPISNIFACIEGFAEPDHYVVIGAQRDAWGPG-AAKSAVGTAILLELVRTFSSMVSN-GFRPRRSLLFISWDGGDFGSVGATEWLEGYLSVLHLKAVVYVSLDNS--VLGDGKFHAKTSPLLVSLIENILKQVDSPN--HSGQTLYEQVALTHPSWDAEVIQP-----LPMDSSAYSFTAFAGVPAVEFSFMEDD-----RVYPFLHTKEDTYENLHKMLRGRLPAVVQAVAQLAGQLLIRLSHDHLLPLDFGRYGDVVLRHIGNLNEFSGDLKER------GLTLQWVYSARGDYIRAAEKLRKEIYSSERN--DERLMRMYNVRIMRVEFYFLSQYVSPADSPFRHIFLGQGDH------TLGALVDHLRMLRADGSGAASSRLTAGLGFQESRFRRQLALLTWTLQGAANALSGDVWNIDNNF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UP52-1", "uniprot_id": "TFR2_HUMAN", "id": "Q9UP52-1", "name": "Transferrin receptor protein 2", "aln": "--------MERLWGLFQRAQQLSPRSSQ--TVYQRVEGPRKGHLEEEEEDGEEGAETLAHFCPMELRGPEPLGSRPRQPNLIPWAAAGRRAAPYLVLTA---LLIFTGAFLLGYVAFRGSCQACGDSVLVVSEDVNYEPD-----------LDFHQG-RLYWSDLQAMFLQFLGEGRLEDTIRQTSLR---ERVAGSAGMAALTQDIRAALS--RQKLDHVWTDTHYVGLQFPDPAHPNTLHWVDEAGKVGEQLPLEDPD------------VYCPYSAIGNVTGELVYAHYGRPEDLQDLRARGVD-PVGRLLLVRVGVISFAQKVTNAQDFGAQGVLIYPEPADFSQDPPKPSLSSQQAVYG----------HVHLGTGDPYTPGFPSFN-QTQFPPVASSGLPSIPAQPISADIASRLLRKLKGPVAPQEWQGSLLGSPYHLG----------PGPRLRLVVNNHRTSTPINNIFGCIEGRSEPDHYVVIGAQRDAWGPG-AAKSAVGTAILLELVRTFSSMVSN-GFRPRRSLLFISWDGGDFGSVGSTEWLEGYLSVLHLKAVVYVSLDNA--VLGDDKFHAKTSPLLTSLIESVLKQVDSPN--HSGQTLYEQVVFTNPSWDAEVIRP-----LPMDSSAYSFTAFVGVPAVEFSFMEDD-----QAYPFLHTKEDTYENLHKVLQGRLPAVAQAVAQLAGQLLIRLSHDRLLPLDFGRYGDVVLRHIGNLNEFSGDLKAR------GLTLQWVYSARGDYIRAAEKLRQEIYSSEER--DERLTRMYNVRIMRVEFYFLSQYVSPADSPFRHIFMGRGDH------TLGALLDHLRLLRSNSSGTPG--ATSSTGFQESRFRRQLALLTWTLQGAANALSGDVWNIDNNF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TIL0-1", "uniprot_id": "A0AB32TIL0_DANRE", "id": "A0AB32TIL0-1", "name": "Transferrin receptor protein 1", "aln": "----MAGTIGQAKMKFSRMVN--SRSYSRFNQSQNPDGDG-SRVEVKLAVDGEEEEMDG----------TELGNMQQETYTRSTGRSEPLNKYRILVCVGAALLVFLVGLLIGYSVHRKSDNKSEPLETPCSKEIQAEEPD--------PPQYEPIVPSIDWSDIVKLLNDKLSSKSIEEQLSVYSQIG---RSAGSSVDNKLGDTIHDAFT--KLNMEP-WVDEHYVKLQNPDSSNPNKVWFGNEE--------IGSPK------------GFLAYSETGRREGRVVYANYGEPADLQAVQANEVS-LNGTVVLMRAGRISMAQKVMNVAKLGAVAALIYPDPADYD--------GMDTELYG----------HVHLGSGDPYTPGFPSFN-HTQFAPAKSSGLPEILAQTIPASMARKILSKMGGSEVPSKFKGGFTSYKFGD-----------ESNKVALSINNKLVDTKIHNVFGVIKGYVDPDRYVVIGAQRDSMTSG-YAKSAVGTTLLMELARVFNELKKE-GFKPKRSIVFASWTAGDFGKVGATEWLEGYWASLDRKAFTYISLDGV--VSGKDSLRASASPLLHTLLQKTLEKVKAP------MPSYG------SDFSSILTN------MQMDDGAYPFLTFSGIPSVSFSFISSRT---TPDYKYFGTEMDTKERLDFVTGQQVVKLSMLAAQVAGQMALRLVHDQILRLDVTKYGGVIESHVKNIINHVNDLKSEKVEKIETLSTEWLIAAKSSYSRAATKLNNDIKNSDLE--DMEMCRIINNRIMKVEHNFLSPYVSIRDFPFRHIFFGNGWQ------TATDLENYLQDVRDKKA-----------SFDIDQVLNKFALLTWSIQGCANDLAGDIWSLDNEI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y3Q0-1", "uniprot_id": "NALD2_HUMAN", "id": "Q9Y3Q0-1", "name": "N-acetylated-alpha-linked acidic dipeptidase 2", "aln": "------------------------------------------------------------------------------MAESRGRLYLWMCLAAALAS-------FLMGFMVGWFIKPLKE---------------------------------TTTSVRYHQSIRWKLVSEMKAENIKSFLRSFTKL---PHLAGTEQNFLLAKKIQTQWK--KFGLDSAKLVHYDVLLSYPNETNANYISIVDEHETEIFKTSYLEPPPDGYENVTNIVPPYNAFSAQGMPEGDLVYVNYARTEDFFKLEREMGINCTGKIVIARYGKIFRGNKVKNAMLAGAIGIILYSDPADY---FAPEVQPYPKGWNLPGTAAQRGNVLNLNGAGDPLTPGYPAKEYTFRLDVEEGVGIPRIPVHPIGYNDAEILLRYLGGIAPPDKSWKGALNVSYSIGPGFTGS---DSFRKVRMHVYNINKITRIYNVVGTIRGSVEPDRYVILGGHRDSWVFG-AIDPTSGVAVLQEIARSFGKLMSKG-WRPRRTIIFASWDAEEFGLLGSTEWAEENVKILQERSIAYINSDSS--IEGNYTLRVDCTPLLYQLVYKLTKEIPSPDDGFESKSLYESWLE--KDPSPENKNLPRINKLGSGSDFEAYFQRLGIASGRARYTKNKKTDKYSSYPVYHTIYETFELVEKFYD-PTFKKQLSVAQLRGALVYELVDSKIIPFNIQDYAEALKNYAASIYNLSKKHDQQLTD--HGVSFDSLFSAVKNFSEAASDFHKRLIQVDLN--NPIAVRMMNDQLMLLERAFIDPLGLPGKLFYRHIIFAPSSHNKYAGESFPGIYDAIFDIENKANS----------RLAWKEVKKHISIAAFTIQAAAGTLKEVL-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04609-1", "uniprot_id": "FOLH1_HUMAN", "id": "Q04609-1", "name": "Glutamate carboxypeptidase 2", "aln": "---------------------------------------------------------------------MWNLLHETDSAVATARRPRWLCAGALVLAGG----FFLLGFLFGWFIKSSNE---------------------------------ATNITPKHN--MKAFLDELKAENIKKFLYNFTQI---PHLAGTEQNFQLAKQIQSQWK--EFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADY---FAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGN---FSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFG-GIDPQSGAAVVHEIVRSFGTLKKEG-WRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSS--IEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTK--KSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYD-PMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKT--YSVSFDSLFSAVKNFTEIASKFSERLQDFDKS--NPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDP----------SKAWGEVKRQIYVAAFTVQAAAETLSEVA-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UQQ1-1", "uniprot_id": "NALDL_HUMAN", "id": "Q9UQQ1-1", "name": "Aminopeptidase NAALADL1", "aln": "---------------------------------------------------------------------------------MQWTKVLGLGLGAAALLG--------LGIILGHFAIPKKAN--------------------------------SLAPQDLDLEILETVMGQLDAHRIRENLRELSRE---PHLASSPRDEDLVQLLLQRWKDPESGLDSAEASTYEVLLSFPSQEQPNVVDIVGPTGGIIHSCHRTEENVTGEQGGPDVVQPYAAYAPSGTPQGLLVYANRGAEEDFKELQ-TQGIKLEGTIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETFPNSWYLPPSGVERGSYYEY--FGDPLTPYLPAVPSSFRVDLANVSGFPPIPTQPIGFQDARDLLCNLNGTLAP-ATWQGALGCHYRLGPGFRPDGDFPADSQVNVSVYNRLELRNSSNVLGIIRGAVEPDRYVLYGNHRDSWVHG-AVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGLIGSTEFTEEFFNKLQERTVAYINVDIS--VFANATLRVQGTPPVQSVVFSATKEIRSP--GPGDLSIYDNWIRYFNRSSPVYGLVPSLGSLGAGSDYAPFVHFLGISSMDIAYTYDRSKTSARIYPTYHTAFDTFDYVDKFLD-PGFSSHQAVARTAGSVILRLSDSFFLPLKVSDYSETLRSFLQ---AAQQDLGALLEQ--HSISLGPLVTAVEKFEAEAAALGQRISTLQKGSPDPLQVRMLNDQLMLLERTFLNPRAFPEERYYSHVLWAPRTG---SVVTFPGLSNACSRARDTASG----------SEAWAEVQRQLSIVVTALEGAAATLRPVADL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0N4SUJ3-1", "uniprot_id": "A0A0N4SUJ3_MOUSE", "id": "A0A0N4SUJ3-1", "name": "", "aln": "MGENEAGLPNMSLQGKKMAYQKVKADLRTSGHSQYLDNDELQATALDLEWDMEKELEEPGFDQFQPDSAEHQNLGHSETLDLHLDSIQPATSPKGRFQR----LQEESDCVTHYTRSAPKNNHCSFCYMLKILCIATTLFIFGIIIGYYAHMNCPSDASPSGTNNPQLYQDILKTIKAEDIKKSFRNW---LQLYDSKDDMEIAKKIKSHWI--ALGLEDTQFINYSVLLDFPGSSPGTITLSSTGQCFYPDGQPCREEARGGHSQ--DLFFSYAAYSAKGTLQGDVIDVSYGTMDDLKRITKLKN--TTNQIALLKLGKLPLLYKISLLEKAGFGGALLYIDPCDAAESSVLSSEPFVVTLNP---------------GGDPSTPGYPSHDGSFRKS---RTNLTSLLVQPISPSLVKMLISLPKLKMDKDACSPLELPH--------------NEKRTVSLQVQTVTQFKTVSNVVGYLRGLTSPDRYIIVGSNHHAGYSYKGQEWASSTAVITAFIEAMMLRVKK-GWRPERTIVFCSWGGTPWGKIGSYEWGEDFVKILQKNAVAYIGLHSP--IRGNSSLYPVVSPSLQQLVIEKIKFTCMQR---------------AQCLGANVSS------VQIQGDADYFINHLGVPTVQFAYEDIKT---LEGPSFLSEAIFPTHATKIEEVDPSFSLHEAITKLSGEVILQIANEPILPFNALDIALGVQNSLKGNEPSVPHLLALASR---------LRESAELFQSDEMRPANDPKERAPS-----RVRMLNDILQDLEKNFLVQWVPPG--FYRNILYHLDEKTN----QFSILKEAWEHCNPQTSN-------ETFQEALSNVLNSINSAHISFKVGLDVFESVLLGKN---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ACN8-1", "uniprot_id": "A0A8I6ACN8_RAT", "id": "A0A8I6ACN8-1", "name": "", "aln": "MGENEAGLPNMALQGKKMAYHKVKADLRTSGHSQYLDSDDLQATALDLEWDMEKELEEPSFDQFQTDNAEHQNLGHSETLDLHLDSIQPATSPKGRFQR----LQEESDCVTHYTRSAPKNNHCNFCYLLKILCIATTLFIFGIIIGYYAHMNCPSDASPSGTNNPQLYQDILKTIKAEDIKKSFRNL---LQVYDSEDDMEISKKIKSHWI--ALGLEDTQFINYSVLLDCPGPSPGTITVSSTGQCFYPDGQPCREEARRGQSQ--DLFYSYAAYSAKGTLQADVIDVSYGTMDDLKRITKLKN--TTNQIALLKLGKLPLLYKISLLEKAGFGGALLYIDPCDAPESAVLSSEPFMVTLNP---------------GGDPSTPGYPSHDESFRQS---RPNLTSLLVQPISASLATVLISSPKLRMDKDVCRPLELPH--------------NEKRTVSLQVQTVTKFKTVSNVVGYLRGLTSPDRYIIVGSNHHAGHSYNGQEWASSTAVITAFIEALMLRVKK-GWRPERTVVFCSWGGTPWGKIGSYEWGEDFAKILQKNAVAYVSIHSP--IRGNSTLYPVASPSLQQLVLEKNKFNCVRR---------------AQCPGANVSS------VQIQGDAEYFVNHLGVPTVQFAYEDIKA---LEGPSFLSEAIFPKHATKIEELDPSFNLHEVITKLSGEVILQIANDPVLPFNALDIALGVQNSLKDNEPSVPNLLALASK---------LRDSAELFQSDEMRPANDPKERVPS-----RVRMLNDILQDLEKNFLVQRVPPG--FYRNILYHLDEKTS----QFSILKEAWEQCIPETSN-------ETLQEALSTVLNSINSAHTFFKTGLDVFESVLLEKN---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q58DX5-1", "uniprot_id": "NADL2_HUMAN", "id": "Q58DX5-1", "name": "Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2", "aln": "MGENEASLPNTSLQGKKMAYQKVHADQRAPGHSQYLDNDDLQATALDLEWDMEKELEESGFDQFQLDGAENQNLGHSETIDLNLDSIQPATSPKGRFQR----LQEESDYITHYTRSAPKSNRCNFCHVLKILCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQEILKTIQAEDIKKSFRNL---VQLYKNEDDMEISKKIKTQWT--SLGLEDVQFVNYSVLLDLPGPSPSTVTLSSSGQCFHPNGQPCSEEARKDSSQ--DLLYSYAAYSAKGTLKAEVIDVSYGMADDLKRIRKIKN--VTNQIALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCDLPKTVNPSHDTFMVSLNP---------------GGDPSTPGYPSVDESFRQS---RSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLELPN--------------NEIRVVSMQVQTVTKLKTVTNVVGFVMGLTSPDRYIIVGSHHHTAHSYNGQEWASSTAIITAFIRALMSKVKR-GWRPDRTIVFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSP--IRGNSSLYPVASPSLQQLVVEKNNFNCTRR---------------AQCPETNISS------IQIQGDADYFINHLGVPIVQFAYEDIKT---LEGPSFLSEARFSTRATKIEEMDPSFNLHETITKLSGEVILQIANEPVLPFNALDIALEVQNNLKGDQPNTHQLLAMALR---------LRESAELFQSDEMRPANDPKERAPI-----RIRMLNDILQDMEKSFLVKQAPPG--FYRNILYHLDEKTS----RFSILIEAWEHCKPLASN-------ETLQEALSEVLNSINSAQVYFKAGLDVFKSVLDGKN---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08693-1", "uniprot_id": "TRE2_YEAST", "id": "Q08693-1", "name": "Putative zinc metalloprotease TRE2", "aln": "---MRSSYQPVSTTNFEHENAIPTASSSHNLLMSQRFDDSPPSSNDNSIETNITPPPEPPSYEFDIEDPHDDLHKRTHLQRVSIGFQEKILEPLMENIIHP--LLQISKFVPDKADYYLSKIGNPFILRRFFYIIFMSFIAYYVLSSGYLFNEKASGSKGMFSQHDILFEYAKKSVDLAKFERDLEYISSMPHGSGTKGDAAIYRYIQESFD--NNGLKLVKEMGYSVYSNYPGNVSISYYDNKNEKHDLELSKENFNPLS----------------SNGKLSKVSLIYGGKGTTYDLQHLKDSKTIEDGKDYVLLLQYDKLVSQQVLIAEKFGAKAVIFISEPYGENIDVVQSKPVGLPQYST----------------GDASGLNWDGSP--VEEKDHKFWRQTHIPTIPISTRQGKELLSRLSSGGVTVDDGNSDRSNSGKMG---------DVLIDVDLQTN-VREKHFIPNIVGKIEGREQSDKAIIIAASRNSINFG-TTYPNFGTAALLSIVQLFQEVKYKFGWKPLRNIYFISFGGTEFNYAGSSELVEQRLTPLKDEIYSLIDISQLGIPFAEKYENGKTRGELSIETHPLLKKFFNRN--------------AHGNFDISVDN------VQHYGDWTPFLAN-GIPVSVISSDSTRN----RDTPTETSEDKFERVEKILEDEQNQQSVKDLLVYLLHISMELIDDPLLHFDIISYVEDIDERLQRLEQAYPEKLNFTSIIKGLLFWKKIGSEWASWTQGWENIVWSHGDGIEPSLLSINRWTWNKKLTNIGRRTCSPAGLPNRSFYKNVLFGPTLIQE-DKSKNGGNVDFWTFPGVMDAIY---------DDDWKRAQEQIDLIGKVLHQSAALFVEETNDIGYK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : : :. : * . . . . : :: . *: : : : . . :. : **. . . . : . .* :: : : *:.. : * ..*: :: . :.: .. : : . : . ::* *.: * *: . :. *: * * *. . :. . : : : . : *:. . .: .. : :. : . : : * : : : ::: : . : .. : ", "identical_positions": 18, "similar_positions": 101, "identity": "2.01%" }, { "cls_id": "homologset.agr.SGD:S000005783", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RCW6-1", "uniprot_id": "M0RCW6_RAT", "id": "M0RCW6-1", "name": "Centrin-3", "aln": "RGGRASVPQRGQGGRGREAESGADEECRASDLGGPRLPQRRSPSEVSRGFPHASAGFGPGRLLPPESHRRARLSARVPWHAVLWASWVDLVSVTPSSHFRTSPLPIGSSPCPSTLKGAPGPRISLGGELVVDKTKRKKRRELSEEQKQEIKDAFELFDTDKDQAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIMTGDI--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35648-1", "uniprot_id": "CETN3_MOUSE", "id": "O35648-1", "name": "Centrin-3", "aln": "------------------------------------------------------------------------------------------------------------------------MSLALRGELVVDKTKRKKRRELSEEQKQEIKDAFELFDTDKDQAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIMTGDI--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15182-1", "uniprot_id": "CETN3_HUMAN", "id": "O15182-1", "name": "Centrin-3", "aln": "------------------------------------------------------------------------------------------------------------------------MSLALRSELVVDKTKRKKRRELSEEQKQEIKDAFELFDTDKDEAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIMTGDI--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06704-1", "uniprot_id": "CDC31_YEAST", "id": "P06704-1", "name": "Cell division control protein 31", "aln": "-------------------------------------------------------------------------------------------------------------------------MSKNRSSLQSGPLN----SELLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGRHLMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKELGETLTDEELRAMIEEFDLDGDGEINENEFIAICTDS---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "M9PGG8-1", "uniprot_id": "M9PGG8_DROME", "id": "M9PGG8-1", "name": "EF-hand domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------MEQNSTAAGNANPATVPAKRGTQQGRKKSGPKFELSEAQKCDIKEAFDLFDNEGTGYIEVKELKVAIRALGFEPKKEEIKRMISDIDKDCSGRIAFNVFLQLMTIKMAEKDTKEEILKAFRLFDDDDTGKISFRNLKRVARELGETLTDEELREMIDEADLDNDGEVNQEEFLRIMKKTSLY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ** * ** :* :**.*** : :: :*****::****: * :: ::.: * : : :: * :: : ::*. :** :**:*****.:****::**:***:****.::***** **:* * *.***:*::**: * . ", "identical_positions": 63, "similar_positions": 47, "identity": "21.8%" }, { "cls_id": "homologset.agr.SGD:S000005784", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K4H4-1", "uniprot_id": "APTX_RAT", "id": "Q8K4H4-1", "name": "Aprataxin", "aln": "------------------------------------------------------------MRVCWLVRQDCWHQRIKLPHLEAVVIGRSPETKITDKKCSRQQVQLKAECNKRYVNVKQMGVNPTSIDEVVIGKDREMKLLPG--QVLHMVNELYPYMVEFEEVAESP-NVTQRKRKRP-DCDSQE----MEAEAG------ASPSQCSVSPKTGKHGAAKEESLGHWSQGLKISMKDPKMQVYKDDQVVVIKDKYPKARHHWLVLPWASISSLKVVTSEHLELLKHMHAVGEKVIADFTGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIKMVQEAG---RVTVKDGTCELLKLPLRCHECQQLLPSIPQLKEHLRKHWGG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TQC5-1", "uniprot_id": "APTX_MOUSE", "id": "Q7TQC5-1", "name": "Aprataxin", "aln": "---------------------------------------------MPEA--------VAKMRVCWLVRQDSRHQRIKLPHLEAVVIGRSPETKITDKKCSRQQVQLKAECNKGYVKVQQMGVNPTSIDSGVIGKDQEKKLLPG--QVLHMVNGLYPYIVEFEEVAESP-NLTQRKRKRS-DCDSEE----MEAESGTGLAPGSSPSQCSVSPKKDKNGATKKESLGHWSQGLKMSMKDPKMQVYKDDQVVVIKDKYPKARHHWLVLPWASISSLKVVTSEHLELLKHMHAVGEKVIADFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIKMVQEAG---RVTVKDGTCELLKLPLRCHECQQLLPSIPQLKEHLRKHWGG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z2E3-1", "uniprot_id": "APTX_HUMAN", "id": "Q7Z2E3-1", "name": "Aprataxin", "aln": "---------------------------------------------MSNVNLSVSDFWRVMMRVCWLVRQDSRHQRIRLPHLEAVVIGRGPETKITDKKCSRQQVQLKAECNKGYVKVKQVGVNPTSIDSVVIGKDQEVKLQPG--QVLHMVNELYPYIVEFEEEAKNPGLETHRKRKRSGNSDSIERDAAQEAEAGTGLEPGSNSGQCSVPLKKGKDAPIKKESLGHWSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIEMVQEAG---RVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHWTQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61799-1", "uniprot_id": "APTX_DANRE", "id": "P61799-1", "name": "Aprataxin", "aln": "------------------------------------------------------------MPVCLLVSEDNSHKPIELHHQQSVTLGRGPDTKIKDKKCSREQVELRADCNRGFVTVKQLGVNPTLVDDVVVGKGNQVSIKPG--QSLYMVNQQYPYSVKFTEDTSRS---KPSKRAQQIQSPTKT-----TADVS------DSPP---PPKKTTPPAGEKSESAGHWSQGLKASMQDPKMQVYKDDSVVVIKDKYPKARYHWLVLPWQSISSLKALRSEHVELLKHMQRVADQMVEQCPDAHKLSFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFTTDYFVESQDVISMLEHDG---KVQVKEGAGELLKLPLRCHVCGKEQTTIPKLKDHLKTHLPS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08702-1", "uniprot_id": "APTX_YEAST", "id": "Q08702-1", "name": "Aprataxin-like protein", "aln": "---------------------------------------------------------------------MSWRYALKNYVTSPETVNDDTVTYFDDKVSIIRDSFPKSECHL-LILPRTMQLSRSHPTKVIDAKFKN----------------------EFESYVNSA----------------------------------------------------IDHIFRHFQEKFRIKKSDDDKDPCWDD---ILKDKNKFVRN--------------------------------------------FVQVGIHSVPSMANLHIHVISKDFHSVRLKNKKHYNSFNTGFFISWDDLPLNGKNLG---TDKEIETTYLKEHDLLCCYCQRNFSNKFSLLKKHLELEFNSHFELK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8MSG8-1", "uniprot_id": "APTX_DROME", "id": "Q8MSG8-1", "name": "Aprataxin-like protein", "aln": "MSWSSALIKDISKPENLIISSEIAVVIADKFPKAQHHYLVLPLADIPSIFHLNRSHLSLLEELHLLARNVVEVKGVRWQDFNVGFHAEPSMQRLHLHVISKDFVSTSLKTKKHWNSFNTELFVPYTKLYAQLEKENSISRLPKSLKDELLAKPLICNQCEFVARNLPSLKGHLVGHLQDPKSVCQRVRLGNQFFPTAGYRTSELAYCFDFVDFYEYKKQMEVDKLAYIRDELQRKLNDKRNFLIESDRAVVMKADYPKSQYHFRVVAKEEFRDITQLTEAQLPLLDHMMDLANQIIEKQKHLESRNFLIGFKVNTFWNRLNLHVISNDFYSMAMKRISHWNSFNTELFMPFQIAYMMLSVQGSIESISEETYNNLQEKTPLRCNQCEFVTNMLLDLKAHLYQHWQRKEDERDQKKKVDKIIQMISETKLDEAEAKPKLLNEEEPIQAQPVAAIAQYPNEHLGKPLTPQQQPGKQQAQNVYDKNINGPSVNMMNQNNPNNPFRNTPHLNRQSQKPPHPRSGPRGPMAPWTGPRFPCHQQQNRFRPPGFNACRQPYPPYHSGHQQFPNASSVGGGQTGLPGQGQGPRPKWNSNKIFNQQNRQNTVQAQPQAQNQQTNQQQIQNSNKNQTPKKKPWKNRLQPVGKVQNQGGANRDPAPPSNSKPS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . . : : . : . . * .. :* . . : : :: . .* .: ::* . : . :* : . .:::****:** * :*. .*:***.* *: : . * : * * : ** ** . ", "identical_positions": 26, "similar_positions": 47, "identity": "3.93%" }, { "cls_id": "homologset.agr.SGD:S000005785", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V6W6-1", "uniprot_id": "G3V6W6_RAT", "id": "G3V6W6-1", "name": "26S proteasome regulatory subunit 10B", "aln": "---------------------------------MALPGIPYERRLLIMAD-PRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62333-1", "uniprot_id": "PRS10_HUMAN", "id": "P62333-1", "name": "26S proteasome regulatory subunit 10B", "aln": "-----------------------------------------------MAD-PRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62334-1", "uniprot_id": "PRS10_MOUSE", "id": "P62334-1", "name": "26S proteasome regulatory subunit 10B", "aln": "-----------------------------------------------MAD-PRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9W414-1", "uniprot_id": "Q9W414_DROME", "id": "Q9W414-1", "name": "", "aln": "---------------------------------MTVTATP-------MPDNLRVKALSEYRKKLLEHKEIEGRLKEKREEIKDLTKLYDKSENDLKALQSVGQIVGEVLKQLTEDKFIVKATNGPRYVVGCRRQLDKAKLKSGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGDVTYSAIGGLTDQIRELREVIELPLLNPELFLRVGITPPKGCLLYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDSLGQVKMIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARLEILKIHALKIAKHGEIDYEAIVKLSDNFNGADLRNVCTEAGLFAIRAEREYVIQEDFMKAVRKVSDNKKLESKLDYKPV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTQ9-1", "uniprot_id": "Q9VTQ9_DROME", "id": "Q9VTQ9-1", "name": "", "aln": "---------------------------------MSAPLAN------PPTDDERVRALTNYRTKLLEHREIESKLKALRDKYKVVNAEYEKSEDDLKALQSVGQMVGEILKQLTPDNFIVKASNGPRYVVGCRRQINKEKLKPGTRVALDVTTLTIMRYLPREVDPLVYNMTHEDPGNVNYAEIGGLGQQIRELREVIELPLLNPDIFLRVGISPPKGCLLYGPPGTGKTLLARAIASQMDANFLKVVSSAIVDKYIGESARLIREMFAYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDALGQVKMIMATNRPDTLDPALLRPGRLDRKLEIPLPNEVARMDILKIHAEPLNKRGEIDYEAVVKLSDLFNGADLRNICTEAGLFALRCDREFVIQEDFMKAVRKIADNKKLESRLDYKPI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53549-1", "uniprot_id": "PRS10_YEAST", "id": "P53549-1", "name": "26S proteasome subunit RPT4", "aln": "MSEEQDPLLAGLGETSGDNHTQQSHEQQPEQPQETEEHHEEEPSRVDPEQEAHNKALNQFKRKLLEHRRYDDQLKQRRQNIRDLEKLYDKTENDIKALQSIGQLIGEVMKELSEEKYIVKASSGPRYIVGVRNSVDRSKLKKGVRVTLDITTLTIMRILPRETDPLVYNMTSFEQGEITFDGIGGLTEQIRELREVIELPLKNPEIFQRVGIKPPKGVLLYGPPGTGKTLLAKAVAATIGANFIFSPASGIVDKYIGESARIIREMFAYAKEHEPCIIFMDEVDAIGGRRFSEGTSADREIQRTLMELLTQMDGFDNLGQTKIIMATNRPDTLDPALLRPGRLDRKVEIPLPNEAGRLEIFKIHTAKVKKTGEFDFEAAVKMSDGFNGADIRNCATEAGFFAIRDDRDHINPDDLMKAVRKVAEVKKLEGTIEYQKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :** ::: *****:. :.:** *:: : : *:*:*:*:*****:**::**::*:*: :::****:.****:** *..::: *** *.**:**:******* ****.*******: : *::.: **** :************* **::* **** **** **************:*:*: :..**: :*.***********:***** **::*:********:**************************.****** * :.*:***********************:.* **** .*::*:***: : * **:*:** **:** *****:** .****:**:* :::.: :*:******::: ****. ::*: :", "identical_positions": 240, "similar_positions": 98, "identity": "54.92%" }, { "cls_id": "homologset.agr.SGD:S000005786", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70541-1", "uniprot_id": "EI2BG_RAT", "id": "P70541-1", "name": "Translation initiation factor eIF2B subunit gamma", "aln": "-MEFQAVVMAVGG-------------------------GSRMTDLTS----------------SIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTKDVQKALCAEFK-------------------------MKLKPDIVCIPDEADMGTADSLRHIYPKLKTDVLVLGCDLITDVALHEVVDLFR-AYDASLAMLMR-KGQESTEPVPGQKGKKKTVEQRDFIGVDSTGKR-----LLFMANEADLDEELVIKGSILQKHPRIHFQTGLVDAHLYCLKKYVVDFLMENKSITSIRSELIPYLVRKQFSSASSQQRQEDKEED--LKKKEPKSLDIYSFIKKDNTLTLAPYDACWNAFRRDKWEDLSRSQVRCY--------VHIMKEGLCSRVSTLGLYMEANRQVPKLLSVLCPEESMIHPSAQIANKHLIGADSLIGSDTQVGEKSSIKRSVIGSSCVIRDRVTVTNCLLMNSVTVEEGSSIHGSVICNNAVVEAGAEIRDCLIGSGQRIEAK----AKRMNEVIVGNDQLMEI----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AUN2-1", "uniprot_id": "B1AUN2_MOUSE", "id": "B1AUN2-1", "name": "Translation initiation factor eIF2B subunit gamma", "aln": "-MEFQAVVMAVGG-------------------------GSRMTDLTS----------------SIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTKDVQKALCAEFK-------------------------MKMKLDIVCIPDEADMGTADSLRHIYPKLKTDVLVLSCDLITDVALHEVVDLFR-AYDASLAMLMR-KGQESIEPVPGQKGKKKPVEQRDFIGVDSTGKR-----LLFMANEADLDEELVIKGSILQKHPRIHFHTGLVDAHLYCLKKYVVDFLMENRSITSIRSELIPYLVRKQFSSASSQQRQEDKEED--LKKKELKSLDIYSFIKKDDTLTLAPYDACWNAFRGDKWEDLSRSQVRCY--------VHIMKEGLCSRVSTLGLYMEANRQVPKLLSVLCPEESMIHSSAQIVNKHLIGADSLIGPDTQIGEKSSIKHSVIGSSCVIRDRTSITNCLLMNSVTVEEGSSIHGSVICNNAVIETGAEIKNCLVGSGQRIEAK----AKRMNEVIVGNDQLMEI----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NR50-1", "uniprot_id": "EI2BG_HUMAN", "id": "Q9NR50-1", "name": "Translation initiation factor eIF2B subunit gamma", "aln": "-MEFQAVVMAVGG-------------------------GSRMTDLTS----------------SIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKALCAEFK-------------------------MKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDLFR-AYDASLAMLMR-KGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKR-----LLFMANEADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSASSQQGQEEKEED--LKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRCY--------VHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVICNNAVIEKGADIKDCLIGSGQRIEAK----AKRVNEVIVGNDQLMEI----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1ZA22-1", "uniprot_id": "A1ZA22_DROME", "id": "A1ZA22-1", "name": "Translation initiation factor eIF2B subunit gamma", "aln": "MTEFQAVVFAAGR-------------------------GTRLPEVLG----------------DAPKCLLPVGPYPLIWYPLNLLQQHNFTEVIVVVLEQEKLEIQSALENTP----------------------LKLRLDYATIPSDGDFGTADSLRYIYDKIKSDFLVVSCDLVSNVSLYPLINKFR-EHDAALAMLLFPSGFESDVVMPGPKSKHK--PERDLIGIHAATQR-----LAFVSAASDCEETLNIQRHLLKNRGRLDVYSRLVDAHVYVLKKWVIDYLRRKENISTFKGEFLPHLIKKQHSKRPPKTVQDTTSEVGVVTKNEDHVLHYVGHTILDQKITQT---SLFNQSLSQ--SPYHGDIVRCYG-------IQAPRDAIGVRVNNTLSFLAINRKLASIWNNLCGEKHPLISPGAVVKSTQT-KEIIAADNAKLSEKTSLNFSVFGPNCIISPKNIVANSLIMSNAIVEEGCNIDNCIIGHRAQVKSGSVLKNCIIGPNYVVEEG----THSQAVHLSNADQFMEIDIQ-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P09032-1", "uniprot_id": "EI2BG_YEAST", "id": "P09032-1", "name": "Translation initiation factor eIF2B subunit gamma", "aln": "-MSIQAFVFCGKGSNLAPFTQPDFPFQTQNKDSTAATSGDKLNELVNSALDSTVINEFMQHSTRLPKALLPIGNRPMIEYVLDWCDQADFKEISVVAPVDEIELIESGLTSFLSLRKQQFELIYKALSNSNHSHHLQDPKKINFIPSKANSTGESLQKELLPRINGDFVILPCDFVTDIPPQVLVDQFRNRDDNNLAMTIYYKNSLDSSIDKKQQQKQKQQQFFTVYSENEDSERQPILLDVYSQRDVTKTKYLQIRSHLLWNYPNLTVSTKLLNSFIYFCSFELCQLLKLGPQSMSRQASFKDPFTGNQQQQNPPTTDDDEDRNHD-DDDDYKPSATSIQPTYFKKKNDLILDPINCNKSLSKVFRDLSRRSWQHSKPREPIGIFILPNETLFIRANNLNAYMDANRFVLKIKSQTMFTKNIQIQSAAIG------ADAIVDPKCQISAHSNVKMSVLGTQANIGSRCRVAGSLLFPGVHLGDEVILENCIIGPMAKIGSKCKLSNCYIEGHYVVEPKNNFKGETLANVYLDEDEEDELIYDDSVIAGESEIAEETDSDDRSDEDSDDSEYTDEYEYEDDGLFER", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:**.*:. * :: :: . ** ***:* *:* * *: :: .* *: **. : : : : :: . **...: . : : ::: *.::: **:::::. ::: ** * *** : .. . : *:* . . . :* : : * *: :* : .: . : *:::.:* . : : * . : :..: : :* .. .. :: : .. .. * . : . .: : *... :: ** : .: . : .. : : : . ::. ::.:: **:*... * : ::..*:: .. : : :...:* * : . : :* : :* . . *: *: ", "identical_positions": 54, "similar_positions": 154, "identity": "9.22%" }, { "cls_id": "homologset.agr.SGD:S000005787", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P26516-1", "uniprot_id": "PSMD7_MOUSE", "id": "P26516-1", "name": "26S proteasome non-ATPase regulatory subunit 7", "aln": "MP--ELAVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKK-VLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPN-SVLVIIDVKPKDLGLPTEAYISVEEVHD------DGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTVGTLSQRITNQVHGLKGLNSKLLDIRSYLEKVASGKLPINHQIIYQLQDVFNLLP----------DAS-------LQEFVKAFYLKTNDQMVVVYLASLIRSVVALHNLINNKIANRDAEK-----KEGQEK-EESK-KERKDDKEK------EKSDAAKKEEKKEKK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AEH3-1", "uniprot_id": "D4AEH3_RAT", "id": "D4AEH3-1", "name": "26S proteasome non-ATPase regulatory subunit 7", "aln": "MP--ELAVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKK-VLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPN-SVLVIIDVKPKDLGLPTEAYISVEEVHDLSLFSQDGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTVGTLSQRITNQVHGLKGLNSKLLDIRTYLEKVASGKLPINHHIIYQLQDVFNLLP----------DAS-------LQEFVKAFYLKTNDQMVVVYLASLIRSVVALHNLINNKIANRDAEK-----KEGQEK-EESK-KERKDDKEK------EKSD-AKKEEKKEKK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51665-1", "uniprot_id": "PSMD7_HUMAN", "id": "P51665-1", "name": "26S proteasome non-ATPase regulatory subunit 7", "aln": "MP--ELAVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKK-VLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPN-SVLVIIDVKPKDLGLPTEAYISVEEVHD------DGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTVGTLSQRITNQVHGLKGLNSKLLDIRSYLEKVATGKLPINHQIIYQLQDVFNLLP----------DVS-------LQEFVKAFYLKTNDQMVVVYLASLIRSVVALHNLINNKIANRDAEK-----KEGQEK-EESK-KDRKEDKEKD--KDKEKSD-VKKEEKKEKK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P26270-1", "uniprot_id": "PSMD7_DROME", "id": "P26270-1", "name": "26S proteasome non-ATPase regulatory subunit 7", "aln": "MPSQEVSVNKVIVHPLVLLSVVDHFNRMGKIGNQKRVVGVLLGCWRSKGVLDVSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNARERVVGWYHTGPKLHQNDIAINELVRRYCPN-SVLVIIDAKPKDLGLPTEAYISVEEVHD------DGSPTSKTFEHVPSEIGAEEAEEVGVEHLLRDIKDTTVGSLSQKITNQLMGLKGLNAQLRDIKQYLQRVGDSKMPINHQIVYQLQDIFNLLP----------DIT-------NDQFTGTMYVKTNDQMLVVYLASMVRSIIALHNLINNKLANRDAEEGKSDSKEAKEKNKDSKDKDNKETKDKDGKKAEEKADKGKDEGGKGSRK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08723-1", "uniprot_id": "RPN8_YEAST", "id": "Q08723-1", "name": "26S proteasome regulatory subunit RPN8", "aln": "MS---LQHEKVTIAPLVLLSALDHYERTQTKEN-KRCVGVILGDANSS-TIRVTNSFALPFEEDEKNSDVWFLDHNYIENMNEMCKKINAKEKLIGWYHSGPKLRASDLKINELFKKYTQNNPLLLIVDVKQQGVGLPTDAYVAIEQVKD------DGTSTEKTFLHLPCTIEAEEAEEIGVEHLLRDVRDQAAGGLSIRLTNQLKSLKGLQSKLKDVVEYLDKVINKELPINHTILGKLQDVFNLLPNLGTPDDDEIDVENHDRINISNNLQKALTVKTNDELMVIYISNLVRSIIAFDDLIENKIQNKKIQE-----QRVKDK--QSKVSDDSESESG------DKEATAPLIQRKNKKN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : :** : ******.:**::* . * ** ***:** ... .: *:****:**:**:*:..******:*:*** * **:**:*:::****:****: .*: ****.::* * .:*:*:*.* :.:****:**:::*:*:* **:.*.*** *:.. * ******:********::* :.* ** ::***: .****:::* *: **::* ::**** *: :***:***** * ::: :: :****:::*:*::.::**::*:.:**:**: *:. :: :. ::* :** .: .: :. :* * .: ", "identical_positions": 145, "similar_positions": 116, "identity": "40.06%" }, { "cls_id": "homologset.agr.SGD:S000005788", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7C0-1", "uniprot_id": "GPN2_RAT", "id": "D4A7C0-1", "name": "GPN-loop GTPase 2", "aln": "---MA-----GAAPTTAFGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANEGLPYECAVDVGELVGLGDVMDALRLGPNGGLLYCMEYLEANLD-WLRAKLEPLRG--HYFLFDCPGQVELCTHHTSLRSIFSQMAQW-DLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHVNLLSKMDLIEHYG-KLAFNLDYYTEVLDLSYLLDHLA---SDPFFSHYRQLNEKLVQLIEDYSLVSFIPLNIQDKDSIQRVLQAVDKANGYCFGVQEQR----SLEALMSAAVGADFHFSS-------------------------------TLGIQEKYLASSDQTAEQEAMQL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEJ1-1", "uniprot_id": "GPN2_MOUSE", "id": "Q8VEJ1-1", "name": "GPN-loop GTPase 2", "aln": "---MA-----GAAPTTAFGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANDGLPYECAVDVGELVGLGDVMDALRLGPNGGLLYCMEYLEANLD-WLRAKLEPLRG--HYFLFDCPGQVELCTHHTALRSIFSQMAQW-DLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHINLLSKMDLIEHYG-KLAFNLDYYTEVLDLSYLLEHLA---SDPFFRRYRQLNEKLVQLVEDYSLVSFIPLNIQDKDSIQRVLQAVDKANGYCFGVQEQR----SLEAMMSAAMGADFHFSS-------------------------------TLGIQEKYLAPSEQTAEQEAMQL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H9Y4-1", "uniprot_id": "GPN2_HUMAN", "id": "Q9H9Y4-1", "name": "GPN-loop GTPase 2", "aln": "---MA-----GAAPTTAFGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANEGLPYECAVDVGELVGLGDVMDALRLGPNGGLLYCMEYLEANLD-WLRAKLDPLRG--HYFLFDCPGQVELCTHHGALRSIFSQMAQW-DLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHINLLSKMDLIEHYG-KLAFNLDYYTEVLDLSYLLDHLA---SDPFFRHYRQLNEKLVQLIEDYSLVSFIPLNIQDKESIQRVLQAVDKANGYCFRAQEQR----SLEAMMSAAMGADFHFSS-------------------------------TLGIQEKYLAPSNQSVEQEAMQL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PUR6-1", "uniprot_id": "GPN2_DANRE", "id": "Q6PUR6-1", "name": "GPN-loop GTPase 2", "aln": "--MMS-----SDPPSLRFGQVVIGPPGSGKTTYCRGMQEFLSRLGRKVVIVNLDPANEGLPYPCAVDIAELVTLDDVMDGLKLGPNGGLIYSMEYLEANLD-WLENKLKLHHD--CYFLFDCPGQVELYTHHNSVKNIFAQLSKW-NFRLTAVHLVDSHYCADPAKFISVLCTSLSTMLHVELPHVNVLSKMDLIEQYG-KLAFNLDFYTEVLDLSYLVEHLS---ADPFFRNFNHLNVKLAEVIQDYSLVSFVPLNVQDKESMMQVLRTVDKANGYCFGDLEER----NLQAMMSAAVGADFQFST-------------------------------TLGVQEKYLDATKNHVEDEVMDL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VU67-1", "uniprot_id": "Q9VU67_DROME", "id": "Q9VU67-1", "name": "GPN-loop GTPase 2", "aln": "--MMQRFPTQATVENPRYGQLIIGPPGSGKTTYCGEALKFYRELGRQVGVVNLDPANENMSYEPVLSVMELITVEDCMEHLKLGPNGALMHCAEYLADHLEDWLLPALRKLSATYNYFLFDCPGQVELYTHHNAMARIFERLERE-RYSLVTVNLIDSHYCSEPAKFIATLLMALNTMLRMSLPHVNVLSKADLLKKHETKLHFNVDYYTDVLDLKYLLDKLD---DDPAMRKYRKLNAAICSMVEDYALVSFQLLDVFSTDSMLRLRNHIDKANGYVYKAGEEQ----TVNSLLACAVGAETEAAR-------------------------------MEHDVQPYME---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08726-1", "uniprot_id": "GPN2_YEAST", "id": "Q08726-1", "name": "GPN-loop GTPase 2", "aln": "MP---------------FAQIVIGPPGSGKSTYCNGCSQFFNAIGRHSQVVNMDPANDALPYPCAVDIRDFITLEEIMQEQQLGPNGGLMYAVESLDNSIDLFILQIKSLVEEEKAYLVFDCPGQVELFTHHSSLFNIFKKMEKELDIRFCVVNLIDCFYMTSPSQYISILLLALRSMLMMDLPHINVFSKIDMLKSYG-ELPFRLDYYTEVQDLDYLEPYIEKEGSSVLGKKYSKLTETIKELVSDFNLVSFEVLSVDDKESMINLQGVIDKANGYIFGASEVGGDTVWAEASREGALIANYDIQDRWIDNKEKYDKEEEEKRTALLKEQELQNKAVDVNEEDEWENALKEWEEKQGMDFVR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* :********:*** :* :**: :**:****: :.* .:.: ::: : : *: :*****.*::. * * :: :: *::********* *** :: ** :: : : .*:*:*..* :.*:::*: * :* :** :.***:*::** *::: : :* *.:*:**:* **.** : . .: :*. : .::.*: **** *.: ..:*: .: :****** : * :: *: *: . : : ", "identical_positions": 90, "similar_positions": 96, "identity": "24.79%" }, { "cls_id": "homologset.agr.SGD:S000005791", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PEC1-1", "uniprot_id": "TBCA_RAT", "id": "Q6PEC1-1", "name": "Tubulin-specific chaperone A", "aln": "---------------------------------MADPRVRQIKIKTGVVKRLVKEKVMYEKEAKQQEEKIEKMKAE-DGENYAIKKQAEILQESRMMIPDCQRRLEAAYTDLRQILESEKD----LEEAEEYKEARIVLDSVKLEA----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48428-1", "uniprot_id": "TBCA_MOUSE", "id": "P48428-1", "name": "Tubulin-specific chaperone A", "aln": "---------------------------------MADPRVRQIKIKTGVVRRLVKERVMYEKEAKQQEEKIEKMKAE-DGENYAIKKQAEILQESRMMIPDCQRRLEAAYTDLQQILESEKD----LEEAEEYKEARVVLDSVKLEA----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75347-1", "uniprot_id": "TBCA_HUMAN", "id": "O75347-1", "name": "Tubulin-specific chaperone A", "aln": "---------------------------------MADPRVRQIKIKTGVVKRLVKEKVMYEKEAKQQEEKIEKMRAE-DGENYDIKKQAEILQESRMMIPDCQRRLEAAYLDLQRILENEKD----LEEAEEYKEARLVLDSVKLEA----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V9U7-1", "uniprot_id": "Q9V9U7_DROME", "id": "Q9V9U7-1", "name": "Tubulin-specific chaperone A", "aln": "---------------------------------MTDPRIRQLVIKSGVVRRLTREKYCYAKEVLTEQARLEKLRGD-GADDHVLRKQEEVIQECIMMVPDSKRRLQKEYEVLEKYLADEQD----LIETDSYKKAAEILKDAKAELET--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48606-1", "uniprot_id": "TBCA_YEAST", "id": "P48606-1", "name": "Tubulin-specific chaperone A", "aln": "---------------------------------MAP---TQLDIKVKALKRLTKEEGYYQQELKDQEAHVAKLKEDKSVDPYDLKKQEEVLDDTKRLLPTLYEKIREFKEDLEQFLKTYQG----TEDVSDARSAITSAQELLDSK----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VXY1-1", "uniprot_id": "Q9VXY1_DROME", "id": "Q9VXY1-1", "name": "Tubulin-specific chaperone A", "aln": "MYNRHIAHLSAVQANDTRHNATLRFQSRPTDNVYSDPRLEQLIVYRALLQHLLQQKDHYDHERELELQRLERFRSE-GANERRLQIQEQVLKKAQGMLPGIVFKMRNEVDKLKRFLDIDKQQELRQLDTALYDNCVELLNNCQSSLENIN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: : :::* ::. * :* : :: ::: : . : :: * :::.. ::* ::. *.: * : :. .. .. . ", "identical_positions": 8, "similar_positions": 41, "identity": "5.33%" }, { "cls_id": "homologset.agr.SGD:S000005795", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63005-1", "uniprot_id": "LIS1_MOUSE", "id": "P63005-1", "name": "Platelet-activating factor acetylhydrolase IB subunit beta", "aln": "-------MVLSQRQRDELNRAIADYLRS-----------NGYEEAYSVFKKEAELDMNEELDKKYAG----------------LLEKKWTSVIRLQKKVMELES----------KLNEAKEEFTSGGPLGQKRDPKE----WIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERT-LKGHTDSVQDISFDHSG---------KLLASCSADMTIKLWDFQG----FECIRTMHGHDHNVSSVAIMPNGD--HIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESS-YSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTG-----------------MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLN-AHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63004-1", "uniprot_id": "LIS1_RAT", "id": "P63004-1", "name": "Platelet-activating factor acetylhydrolase IB subunit alpha", "aln": "-------MVLSQRQRDELNRAIADYLRS-----------NGYEEAYSVFKKEAELDMNEELDKKYAG----------------LLEKKWTSVIRLQKKVMELES----------KLNEAKEEFTSGGPLGQKRDPKE----WIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERT-LKGHTDSVQDISFDHSG---------KLLASCSADMTIKLWDFQG----FECIRTMHGHDHNVSSVAIMPNGD--HIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESS-YSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTG-----------------MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLN-AHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43034-1", "uniprot_id": "LIS1_HUMAN", "id": "P43034-1", "name": "Platelet-activating factor acetylhydrolase IB subunit beta", "aln": "-------MVLSQRQRDELNRAIADYLRS-----------NGYEEAYSVFKKEAELDVNEELDKKYAG----------------LLEKKWTSVIRLQKKVMELES----------KLNEAKEEFTSGGPLGQKRDPKE----WIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERT-LKGHTDSVQDISFDHSG---------KLLASCSADMTIKLWDFQG----FECIRTMHGHDHNVSSVAIMPNGD--HIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESS-YSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTG-----------------MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLN-AHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T394-1", "uniprot_id": "LIS1A_DANRE", "id": "Q7T394-1", "name": "Lissencephaly-1 homolog A", "aln": "-------MVLSQRQRDELNRAIADYLRS-----------NGYEEAYSVFKKEAELDMNEELDKKYAG----------------LLEKKWTSVIRLQKKVMELES----------KLNEAKEEINIGGPIGQKRDPKE----WIPRPPEKYALSGHRSPVTRVIFHPVFSVIVSASEDATIKVWDHETGDFERT-LKGHTDSVQDISFDHTG---------KLLASCSADMTIKLWDFQG----FECIRTMHGHDHNVSSVAIMPNGD--HIVSASRDKTIKMWEVATGYCVKTFTGHREWVRMVRPNQDGTLIASSSNDQTVRVWVVATKECKAELREHEHVVECISWAPESA-HPTILEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSIG-----------------MCLMTLVGHDNWVRGVLVHPGGKYIVSCADDKTLRIWDYKNKRCTKTLS-AHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q803D2-1", "uniprot_id": "LIS1B_DANRE", "id": "Q803D2-1", "name": "Lissencephaly-1 homolog B", "aln": "-------MVLSQRQRDELNRAIADYLRS-----------NGYEEAYSTFKKEAELDVNDELDKKFAG----------------LLEKKWTSVIRLQKKVMELES----------KLNEAKEEITLGGPVGQKRDPKE----WIPRPPEKYALSGHRSPVTRVIFHPVFSLMVSASEDATIKVWDYEAGDFERT-LKGHTDSVQDISFDQTG---------KLLASCSADMTIKLWDFQG----FECIRTMHGHDHNVSSVAIMPNGD--HIVSASRDKTMKMWEVATGYCVKTFTGHREWVRMVRPNQDGTLLASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESA-HPTISEATGSENKKSGKPGPFLLSGSRDKTIKMWDISTG-----------------MCLMTLVGHDNWVRGVLFHPGGRFVVSCADDKTLRIWDYKNKRCMKTLS-AHEHFVTSLDFHKASPYVVTGSVDQTVKVWECR------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KNS3-1", "uniprot_id": "LIS1_DROME", "id": "Q7KNS3-1", "name": "Lissencephaly-1 homolog", "aln": "-----MKMVLSQRQREELNQAIADYLGS-----------NGYADSLETFRKEADLST--EVEKKFGG----------------LLEKKWTSVIRLQKKVMELEA----------KLTEAEKEVIEGAPTKNKRTPGE----WIPRPPEKFSLTGHRASITRVIFHPIFALMVSASEDATIRIWDFETGEYERS-LKGHTDSVQDVAFDAQG---------KLLASCSADLSIKLWDFQQS---YECIKTMHGHDHNVSSVAFVPAGD--YVLSASRDRTIKMWEVATGYCVKTYTGHREWVRMVRVHIEGSIFATCSNDQTIRVWLTNSKDCKVELRDHEHTVECIAWAPEAA-ASAINEAAGADNKKGHHQGPFLASGSRDKTIRIWDVSVG-----------------LCLLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDLRNKRCMKTLY-AHQHFCTSIDFHKAHPYVISGSVDQTVKVWECR------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39946-1", "uniprot_id": "LIS1_YEAST", "id": "P39946-1", "name": "Nuclear distribution protein PAC1", "aln": "MTNWQQQLPLTDTQKNELDKSVLRYLNWNYKQTVRHEHAQDYESVRHAIVTLSGFLLQESVDRQEFISNNDTSNESMVDIDELLLPKKWNSIVRLQKKIIELEQNTETLVSQIKDLNTQVSELAQFKPTTSNGTSAHNVLKWIPRNLPSCLIN-VESSVTSVKLHPNLPIVFVATDHGKLYAFDLFNYTIPLASLQSHTKAITSMDVLFTNYTNSSKKNYLVIVTASKDLQIHVFKWVSEECKFQQIRSLLGHEHIVSAVKIWQKNNDVHIASCSRDQTVKIWDFHNGWSLKTFQPHSQWVRSID--VLGDYIISGSHDTTLRLTHWPSGNGLSVGTGHEFPIEKVKFIHFIEDSPEIRFRTPSTDRYKNWGMQYCVSASRDRTIKIWEIPLPTLMAHRAPIPNPTDSNFRCVLTLKGHLSWVRDISIR--GQYLFSCADDKSVRCWDLNTGQCLHVWEKLHTGFVNCLDLDVDFDSNVTPRQMMVTGGLDCKSNVFMR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:: *::**:::: ** :.* . .: . : : .:::: ** ***.*::*****::*** .*. .*. * .: . . **** . :. .:.:* * :** :.::. *::...: :* : *:.**.:: .: . . ::.:.* *: *:::.: :: *::: **:* **:* : .: :: *.***:*:*:*:. .*:.:**: * :*** : * : : *:* *:*: : : **. :* : : . * : : : : *.***:**::*::. *::** ** .***.: .: *:::.*.:***::* ** .. :* :. * * ..:*:. :: .. :*: ", "identical_positions": 98, "similar_positions": 155, "identity": "19.64%" }, { "cls_id": "homologset.agr.SGD:S000005796", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZND3-1", "uniprot_id": "A0A8I5ZND3_RAT", "id": "A0A8I5ZND3-1", "name": "V-type proton ATPase subunit a", "aln": "---------LRIMGSMFRSEEVALVQLLLPTASAYNCVSQLGELGLVEFRDLNESVSAFQRRFVVEVRRCEELEKTFTFLREEVQRAGLTLTPPE---------GTLPAPPPRDLLRIQEETDRLAQELRDVRGNQQALRAQLHQLQLHSAVLGQS-------------------------HAPPMAAVHTEGPTTERTPLLSATPGPHADLKVNFVAGAVEPCKAAALERLLWRACRGFLIASFKETEGQLEDPVTG---EPATWMTFVISYWGEQIGQKVRKITDCFHCHVFPYLEQEEARLRTLQQLQQQSQELQEVLGETERFLSQVLGRVQQLLPPGQVQIRKMKAVYLTLN---QCSVNTTHKCLIAEVWCATRDLPTVQQALQ------SGSSEEG--VSAVAHRIPCQ--------------------------------DMPPTLIRTNRFTSSFQGIVDAYGVGRYREVNPAPYTIITFPFLFAVMFGDVGHGLLMFLFALAMVLTENQPAVKTT----QNEIWQTFFGGRYLLLLMGLFSIYTGFIYNECFSRATTIFPSGWSVAAMANQSG----------WSDEYLSQH--PMLTLNPNITGVFLG-PYPFGIDPIWSLA-TNHLSFLNSFKMKMSVILGVTHMAFGVFLSIFNHVHFGQAHRLLLETVPELIFLLGLFGYLVFLIVYKWLYVSAASASS------APSILIHFINMFLFSQNPTNR-----LLFHGQVVVQYALVVLALATVPILLLGTPLYLLRQHHRRNTQRRPT-------AGRQDEDSDKLLASPDASTLENSWSPDEEKAGSSGDEE-AEFVPSEIFMHQAIHTIEFCLGCISNTASYLRLWALSLAHAQLSEVLWAMVMRIGLGMGREIGVASVVLVPVFAAFAVLTVAILLVMEGLSAFLHALRLHWVEFQNKFYSGTGYKLSPFAFTVDSD-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13488-1", "uniprot_id": "VPP3_HUMAN", "id": "Q13488-1", "name": "V-type proton ATPase 116 kDa subunit a 3", "aln": "------------MGSMFRSEEVALVQLFLPTAAAYTCVSRLGELGLVEFRDLNASVSAFQRRFVVDVRRCEELEKTFTFLQEEVRRAGLVLPPPK---------GRLPAPPPRDLLRIQEETERLAQELRDVRGNQQALRAQLHQLQLHAAVLRQG-------------------------HEPQLAAAHTDG-ASERTPLLQAPGGPHQDLRVNFVAGAVEPHKAPALERLLWRACRGFLIASFRELEQPLEHPVTG---EPATWMTFLISYWGEQIGQKIRKITDCFHCHVFPFLQQEEARLGALQQLQQQSQELQEVLGETERFLSQVLGRVLQLLPPGQVQVHKMKAVYLALN---QCSVSTTHKCLIAEAWCSVRDLPALQEALR------DSSMEEG--VSAVAHRIPCR--------------------------------DMPPTLIRTNRFTASFQGIVDAYGVGRYQEVNPAPYTIITFPFLFAVMFGDVGHGLLMFLFALAMVLAENRPAVKAA----QNEIWQTFFRGRYLLLLMGLFSIYTGFIYNECFSRATSIFPSGWSVAAMANQSG----------WSDAFLAQH--TMLTLDPNVTGVFLG-PYPFGIDPIWSLA-ANHLSFLNSFKMKMSVILGVVHMAFGVVLGVFNHVHFGQRHRLLLETLPELTFLLGLFGYLVFLVIYKWLCVWAARAAS------APSILIHFINMFLFSHSPSNR-----LLYPRQEVVQATLVVLALAMVPILLLGTPLHLLHRHRRR--LRRRP-------ADRQEENKAGLLDLPDAS--VNGWSSDEEKAGGLDDEEEAELVPSEVLMHQAIHTIEFCLGCVSNTASYLRLWALSLAHAQLSEVLWAMVMRIGLGLGREVGVAAVVLVPIFAAFAVMTVAILLVMEGLSAFLHALRLHWVEFQNKFYSGTGYKLSPFTFAATDD-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P15920-1", "uniprot_id": "VPP2_MOUSE", "id": "P15920-1", "name": "V-type proton ATPase 116 kDa subunit a 2", "aln": "------------MGSLFRSESMCLAQLFLQSGTAYECLSALGEKGLVQFRDLNQNVSSFQRKFVGEVKRCEELERILVYLVQEITRADIPLPEGE---------ASPPAPPLKHVLEMQEQLQKLEVELREVTKNKEKLRKNLLELVEYTHMLRVTKTFLK--------------------RNVEFEPTYEEFPALENDSLLDYSCMQRLGAKLGFVSGLIQQGRVEAFERMLWRACKGYTIVTYAELDECLEDPETG---EVIKWYVFLISFWGEQIGHKVKKICDCYHCHIYPYPNTAEERREIQEGLNTRIQDLYTVLHKTEDYLRQVLCKAAESVCSRVVQVRKMKAIYHMLN---MCSFDVTNKCLIAEVWCPEVDLPGLRRALE------EGSRESGATIPSFMNTIPTK--------------------------------ETPPTLIRTNKFTEGFQNIVDAYGVGSYREVNPALFTIITFPFLFAVMFGDFGHGFVMFLFALLLVLNEN-HPRLSQ----SQEILRMFFDGRYILLLMGLFSVYTGLIYNDCFSKSVNLFGSGWNVSAMYSSSHSPEEQRKMVLWNDSTIRHS--RTLQLDPNIPGVFRG-PYPFGIDPIWNLA-TNRLTFLNSFKMKMSVILGIFHMTFGVVLGIFNHLHFRKKFNVYLVSVPEILFMLCIFGYLIFMIIYKWLAYSAETSRE------APSILIEFINMFLFPTSKTH------GLYPGQAHVQRVLVALTVLAVPVLFLGKPLFLLWLHNGRNCFGMSR-----SGYTLVRKDSEEEVSLLGNQDIEEGNSRMEEGCR---EVTCEEFNFGEILMTQAIHSIEYCLGCISNTASYLRLWALSLAHAQLSDVLWAMLMRVGLRVDTTYGV--LLLLPVMAFFAVLTIFILLVMEGLSAFLHAIRLHWVEFQNKFYVGAGTKFVPFSFSLLSSKFSNDDSIA----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y487-1", "uniprot_id": "VPP2_HUMAN", "id": "Q9Y487-1", "name": "V-type proton ATPase 116 kDa subunit a 2", "aln": "------------MGSLFRSETMCLAQLFLQSGTAYECLSALGEKGLVQFRDLNQNVSSFQRKFVGEVKRCEELERILVYLVQEINRADIPLPEGE---------ASPPAPPLKQVLEMQEQLQKLEVELREVTKNKEKLRKNLLELIEYTHMLRVTKTFVK--------------------RNVEFEPTYEEFPSLESDSLLDYSCMQRLGAKLGFVSGLINQGKVEAFEKMLWRVCKGYTIVSYAELDESLEDPETG---EVIKWYVFLISFWGEQIGHKVKKICDCYHCHVYPYPNTAEERREIQEGLNTRIQDLYTVLHKTEDYLRQVLCKAAESVYSRVIQVKKMKAIYHMLN---MCSFDVTNKCLIAEVWCPEADLQDLRRALE------EGSRESGATIPSFMNIIPTK--------------------------------ETPPTRIRTNKFTEGFQNIVDAYGVGSYREVNPALFTIITFPFLFAVMFGDFGHGFVMFLFALLLVLNEN-HPRLNQ----SQEIMRMFFNGRYILLLMGLFSVYTGLIYNDCFSKSVNLFGSGWNVSAMYSSSHPPAEHKKMVLWNDSVVRHN--SILQLDPSIPGVFRG-PYPLGIDPIWNLA-TNRLTFLNSFKMKMSVILGIIHMTFGVILGIFNHLHFRKKFNIYLVSIPELLFMLCIFGYLIFMIFYKWLVFSAETSRV------APSILIEFINMFLFPASKTS------GLYTGQEYVQRVLLVVTALSVPVLFLGKPLFLLWLHNGRSCFGVNR-----SGYTLIRKDSEEEVSLLGSQDIEEGNHQVEDGCR---EMACEEFNFGEILMTQVIHSIEYCLGCISNTASYLRLWALSLAHAQLSDVLWAMLMRVGLRVDTTYGV--LLLLPVIALFAVLTIFILLIMEGLSAFLHAIRLHWVEFQNKFYVGAGTKFVPFSFSLLSSKFNNDDSVA----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AWJ9-1", "uniprot_id": "A0A8M3AWJ9_DANRE", "id": "A0A8M3AWJ9-1", "name": "V-type proton ATPase subunit a", "aln": "------------MGSGFRSEEMCLAQLFLQSGSAYACISELGEMGLVEFRDLNPSVSSFQRRFVSEIKRCEEMERILGYLLREIRKANIAVPEAE---------VPPVAPAPKNVLEIMEQLQRLEVELSEVAKNKEKLQRNLLELMEYTHMLRITRSFVHSRS-----------------RHEALGPQYEEFPSLETESVTGCTSMQRLGAKLGFVSGLIQRVKVEAFERMLWRVCKGYTILSYAEVDESLADLDTG---EIRKNVVFLISFWGDQIGQKVQKICDCYHCHIYPHPETDEERADVMDSLRTRIQDLHNVLHRTEDYLKQVLHKASESAQSWVLQVKKMKAIYHILN---LCSFDVTNKCLIAEVWCPVSDLANLRRALE------EGSRKGDATVPSFVNRIPSS--------------------------------DTPPTLLRSNKFTSGFQSIVEAYGVGDYREVSPAPFTIITFPFLFAVMFGDLGHGSVLTLFALWMVLTEKDHTRRRP----GNEIRMTLFDGRYIILMMGLFSIYTGLIYNDCFSKSLNIFGSAWSVKAMFTEQE----------WTNETLRSN--MLLTLNPNVSGVFSG-PYPLGIDPIWNMA-VNRLTFLNSYKMKMSVIIGVVHMSFGVVLSVFNHLHFRQKYKIYLLFLPELLFLLCLFGYLAFMIFYKWLAYTARDSQL------APSILIHFINMFLMQANATS------PLYPGQMGLQVFLVVVALLSVPVLLLGKPLYLYWLHHGGKSLGIHRVCLCSCGYERVRRVSEEDLSPSVVHDEEEGLS--ESGG-------PQEFDFGDVFLHQAIHTIEYSLGCISNTASYLRLWALSLAHAQLSEVLWAMVMRLGLRISSRLGV--IFLVPVFSVFAVLTISILLVMEGLSAFLHALRLHWVEFQNKFYSGAGVKFAPFDFSLLPSVFEQDGLL-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q920R6-1", "uniprot_id": "VPP4_MOUSE", "id": "Q920R6-1", "name": "V-type proton ATPase 116 kDa subunit a 4", "aln": "------------MASVFRSEEMCLSQVFLQVEAAYCCVAELGELGLVQFKDLNANVNSFQRKFVNEVRRCESLERILRFLEDEMQN-EILIQVPE---------KDAETPLPREMITLETTLEKLEGELQEANQSHQALKKSFLELTELKYLLKKTQDFFETETN-------------------LGEDFFVEDTSGLLELR---TIPAFMTGKLGFTAGVINRERMASFERLLWRVCRGNVYLKFSEMDTLLEDPVTK---EEIKKNIFIIFYQGEQLRLKIKKICDGFRATIYPCPEHAAERREMLTSVNVRLEDLITVITQTESHRQRLLQEAAANWHSWVIKVQKMKAVYHVLN---MCNIDVTQQCIIAEIWFPVADTRHIKKALE------QGMELSGSSMIPIMTEVETK--------------------------------TDPPTFNRTNKFTAGFQNIVDAYGVGSYREINPAPYTIITFPFLFAVMFGDCGHGMVMLMAALWMVLNERHLLAQKS----TNEMWNIFFNGRYLILLMGIFSIYTGLIYNDCFSKSFNIFGSSWSVQPMFRNG----------TWNTHIVENS--PYLQLDPAIPGVYSGNPYPFGIDPIWNLA-SNKLTFLNSYKMKMSVILGIAHMIFGVILSLFNHIYFRRTLNIILQFIPEMIFMLSLFGYLVFMIIFKWCRYDAHTSRK------APSILIHFIGMFLFDYDDSSNA----PLYGHQQEVQTFFVIIALVSVPWMLLIKPFVLRAKHQ-KSQLQSFT----------IHEDAVEGDHSGHSSK-------KTAGAHGMKDGHEEEFNFGDIFVHQAIHTIEYCLGCISNTASYLRLWALSLAHAELSEVLWTMVMSIGLRLQGWAGL--VGVFIIFAVFAVLTVAILLVMEGLSAFLHALRLHWVEFQNKFYEGAGSKFSPFSFKHVLE---GTAEE-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A1H0-1", "uniprot_id": "D4A1H0_RAT", "id": "D4A1H0-1", "name": "V-type proton ATPase subunit a", "aln": "------------MASVFRSEEMCLSQVFLQVEAAYCCVAELGELGLVQFKDLNANVNSFQRKFVNEVRRCESLERILRFLEDEMQN-EIIIQVPD---------KDPGTPLPREMITLETTLEKLEGELQEANQSHQALKKSFLELTELKYLLKKTQDFFETETN-------------------LGEDFFVEDTSGLLELR---AMPAFMTGKLGFTAGVINRERMASFERLLWRVCRGNVYLKFSEMDTLLEDPVTK---EEIKKNIFIIFYQGEQLRLKIKKICDGFRATIYPCPEHAAERREMLASVNVRLEDLITVITQTESHRQRLLQEAASNWHSWVIKVQKMKAVYHVLN---MCNIDVTQQCIIAEIWFPVADTRHIKKALE------QGMELSGSSMVPIMTEVETK--------------------------------TDPPTFNRTNKFTAGFQNIVDAYGVGSYREINPAPYTIITFPFLFAVMFGDCGHGMVMLMAALWMVLNERHLLAQKS----TNEMWNIFFNGRYLILLMGIFSIYTGLIYNDCFSKSFNIFGSSWSVQPMFRNG----------TWNAHVVEQN--PYLQLDPAIPGVYSGNPYPFGIDPIWNLA-SNKLTFLNSYKMKMSVILGIVHMIFGVILSLFNHIYFRRTLNIILQFIPEMIFMLSLFGYLVFMIIFKWCQYDAHTSQK------APSILIHFIGMFLFDYDDSSNA----PLYGHQQEVQTFFVIIALVSVPWMLLIKPFILRAKHQ-KSQLQSFT----------IHEDAME----GPSVK-------KTAGAHGTKEGHEEEFNFGDIFVHQAIHTIEYCLGCISNTASYLRLWALSLAHAELSEVLWTMVMSIGLRLRGWGGL--VGVFIIFAVFAVLTVAILLVMEGLSAFLHALRLHWVEFQNKFYEGAGFKFSPFSFKHVLE---GAAEE-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HBG4-1", "uniprot_id": "VPP4_HUMAN", "id": "Q9HBG4-1", "name": "V-type proton ATPase 116 kDa subunit a 4", "aln": "------------MVSVFRSEEMCLSQLFLQVEAAYCCVAELGELGLVQFKDLNMNVNSFQRKFVNEVRRCESLERILRFLEDEMQN-EIVVQLLE---------KSPLTPLPREMITLETVLEKLEGELQEANQNQQALKQSFLELTELKYLLKKTQDFFETETN-------------------LADDFFTEDTSGLLELK---AVPAYMTGKLGFIAGVINRERMASFERLLWRICRGNVYLKFSEMDAPLEDPVTK---EEIQKNIFIIFYQGEQLRQKIKKICDGFRATVYPCPEPAVERREMLESVNVRLEDLITVITQTESHRQRLLQEAAANWHSWLIKVQKMKAVYHILN---MCNIDVTQQCVIAEIWFPVADATRIKRALE------QGMELSGSSMAPIMTTVQSK--------------------------------TAPPTFNRTNKFTAGFQNIVDAYGVGSYREINPAPYTIITFPFLFAVMFGDCGHGTVMLLAALWMILNERRLLSQKT----DNEIWNTFFHGRYLILLMGIFSIYTGLIYNDCFSKSLNIFGSSWSVQPMFRNG----------TWNTHVMEES--LYLQLDPAIPGVYFGNPYPFGIDPIWNLA-SNKLTFLNSYKMKMSVILGIVQMVFGVILSLFNHIYFRRTLNIILQFIPEMIFILCLFGYLVFMIIFKWCCFDVHVSQH------APSILIHFINMFLFNYSDSSNA----PLYKHQQEVQSFFVVMALISVPWMLLIKPFILRASHR-KSQLQASR----------IQEDATENIEGDSSSPSSRSGQRTSADTHGALDDHGEEFNFGDVFVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVMNSGLQTRGWGGI--VGVFIIFAVFAVLTVAILLIMEGLSAFLHALRLHWVEFQNKFYVGDGYKFSPFSFKHILD---GTAEE-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z1G4-1", "uniprot_id": "VPP1_MOUSE", "id": "Q9Z1G4-1", "name": "V-type proton ATPase 116 kDa subunit a 1", "aln": "------------MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEEMDRKLRFVEKEIRKANIPIMDTG---------ENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKRNFLELTELKFILRKTQQFFDEAELHHQQ---------------MADPDLLEESSSLLEPN---EMGRGAPLRLGFVAGVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTG---DYVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKMKAIYHTLN---LCNIDVTQKCLIAEVWCPVTDLDSIQFALR------RGTEHSGSTVPSILNRMQTN--------------------------------QTPPTYNKTNKFTHGFQNIVDAYGIGTYREINPAPYTVITFPFLFAVMFGDFGHGILMTLFAVWMVLRESRILSQKH----ENEMFSMVFSGRYIILLMGLFSIYTGLIYNDCFSKSLNIFGSSWSVRPMFTQG----------NWTEETLLGS--SVLQLNPAIPGVFGG-PYPFGIDPIWNIA-TNKLTFLNSFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMSSLFGYLVILIFYKWTAYDAHSSRN------APSLLIHFINMFLFSYPESGNA----MLYSGQKGIQCFLIVVAMLCVPWMLLFKPLILRHQYLRKKHLGTLN----------FGGIRVGNGPTEEDAEIIQHDQLSTHSEDAEE------FDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLHVRSLAGG--LGLFFIFAAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYTGTGFKFLPFSFEHIRE---GKFDE-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25286-1", "uniprot_id": "VPP1_RAT", "id": "P25286-1", "name": "V-type proton ATPase 116 kDa subunit a 1", "aln": "------------MGELFRSEEMTLAQLFLQSEAAYCCVSELEELGKVQFRDLNPDVNVFQRKFVNEVRRCEEMDRKLRFVEKEIRKANIPIMDTG---------ENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKRNFLELTELKFILRKTQQFFDE----------------------MADPDLLEESSSLLEPN---EMGRGAPLRLGFVAGVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTG---DYVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKMKAIYHTLN---LCNIDVTQKCLIAEVWCPVTDLDSIQFALR------RGTEHSGSTVPSILNRMQTN--------------------------------QTPPTYNKTNKFTHGFQNIVDAYGIGTYREINPAPYTVITFPFLFAVMFGDFGHGILMTLFAVWMVLRESRILSQKN----ENEMFSMVFSGRYIILLMGLFSIYTGLIYNDCFSKSLNIFGSSWSVRPMFTIG----------NWTEETLLGS--SVLQLNPAIPGVFGG-PYPFGIDPIWNIA-TNKLTFLNSFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMSSLFGYLVILIFYKWTAYDAHSSRN------APSLLIHFINMFLFSYPESGNA----MLYSGQKGIQCFLIVVAMLCVPWMLLFKPLILRHQYLRKKHLGTLN----------FGGIRVGNGPTEEDAEIIQHDQLSTHSEDAEEPTEDEVFDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLHVRSLAGG--LGLFFIFAAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYTGTGFKFLPFSFEHIRE---GKFDE-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q93050-2", "uniprot_id": "VPP1_HUMAN", "id": "Q93050-2", "name": "V-type proton ATPase 116 kDa subunit a 1", "aln": "------------MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEEMDRKLRFVEKEIRKANIPIMDTG---------ENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKRNFLELTELKFILRKTQQFFDE----------------------MADPDLLEESSSLLEPS---EMGRGTPLRLGFVAGVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTG---DYVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKMKAIYHTLN---LCNIDVTQKCLIAEVWCPVTDLDSIQFALR------RGTEHSGSTVPSILNRMQTN--------------------------------QTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHGILMTLFAVWMVLRESRILSQKN----ENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLNIFGSSWSVRPMFTY-----------NWTEETLRGN--PVLQLNPALPGVFGG-PYPFGIDPIWNIA-TNKLTFLNSFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYKWTAYDAHTSEN------APSLLIHFINMFLFSYPESGYS----MLYSGQKGIQCFLVVVALLCVPWMLLFKPLVLRRQYLRRKHLGTLN----------FGGIRVGNGPTEEDAEIIQHDQLSTHSEDADEPSEDEVFDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGG--LVLFFFFTAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIRE---GKFEE-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BB25-1", "uniprot_id": "A0A8M2BB25_DANRE", "id": "A0A8M2BB25-1", "name": "V-type proton ATPase subunit a", "aln": "------------MGELFRSEEMTLAQLFLQSESAYCCVSELGEIGMVQFRDLNPDVNAFQRKFVNEVRRCEEMDRKLRFVEKEIKKANIPIVDTG---------ENPEVPFPRDMIDLEATFEKLENELKEINTNQEALKKNFLELTELKHILRRTQQFFDE----------------------MEDPSLLEESSTLLDPN---EVGRAAPLRLGFVAGVIGRERIPTFERMLWRVCRGNVFLRQADIEDPLEDPATG---DNVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMAAGVNTRIDDLQMVLNQTEDHRQRVLQAAAKTVRVWFIKVRKMKAIYHTLN---LCNIDVTQKCLIAEIWCPVSDLDSIQFALR------RGTERSGSTVPSILNRMQTK--------------------------------QTPPTYNKTNKFTSGFQSIVDAYGISNYREMNPAPYTIITFPFLFAVMFGDLGHGVLMTCAALYLVLRESRLIAQKN----DSEMFSMVFAGRYIILLMGLFSMYTGIIYNDCFSKSLNIFGSGWSVRPMFGEKGD--------NWTFAVLEKS--NVLQLNPAVPNVFTG-PYPVGIDPIWNIA-TNKLTFLNSFKMKMSIILGVIHMIFGVSLSLFNHLYFRKPLNIYLGFIPEIIFMVSLFGYLVLLIFYKWIAYDAKSSRV------APSLLITFINMCLFSYNDPTNK----PFYTGQVVIQCLLVIIALSCVPCMLIVKTLVMRRQHLWRRHLGTQN----------FGGIHVGNGPTEDEAEIIQHDQLSQNTEEEPEPSEEEVFNFADEAVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWSMVMHMGLSSRSFGGF--IFLSIIFCFFAVLTVFILLVMEGLSAFLHALRLHWVEFQNKFYTGQGFKFMPFTFDSILD---GKSEE-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9P680-1", "uniprot_id": "A0A8M9P680_DANRE", "id": "A0A8M9P680-1", "name": "V-type proton ATPase subunit a", "aln": "-----------MMSCLFRSEEMCLVQLFLQTESAHNCINELGHLGLVQFKDLNPCATAFQRRFVKEVKKCEQMERILRYLEKEMVKSNIVITATK---------EKEMVPCARDVLELESTFEKLEQELREINHNHDTLRQNLIELMDIDSLLRMTEDFFEEAESLLTFSEA------------SSYDSVSMTISSFITSRRNSSSSTSGPLHLGFIAGVIKQERFPAFEKVLWRLFHGNFVLRHAEIQTTEELEAVR---GAVKKDAFIIFVQGDHVREKIRKVCEGFRASLYSCPKTLYERKEMSNSIMTRMEDLRLVLRRTEEYRAGVLSRAAEHVQEWGSKVKKMKAIYYTLN---LCNIDITQKLIVAEIWCPVSDLTVVQNALI------KGSEQSGSSVTPVLNRIQTK--------------------------------QTPPTFNRTNSFTEGFQAIIDAYGVGTYQEINPAPYTIITFPFLFAVMFGDCGHGLLMALFSVWLITQADYIR--KW----KNELTDVLVGGRFIILLMGLFSIYTGLIYNDCFSKSFNIFGSSWCVRPMFHPHG---------SWQNETLHDH--HHLQLNPFVPGVFSGHPYVFGIDPIWNIA-SNKLSFLNSFKMKMSVILGVAHMLFGVTLSLVNFLHFRKFQDILLQFVPQLVFMLCLFGYLIFLILYKWSVS--LSSEM------APSILLLFISMMLFDY-QPDHK----LLYGGQKAVQICLVVTAVLMVPVLLLVKPFLIYRSRMKTRHQ------------------VFGNSLDDQQCT--------DKRSSFARHQKDETVSMGDVFVYQAIHTIEYCLGCISNTASYLRLWALSLAHAELSEVLWRMVLQAGLKLSFGLGS--LMLALLFAAFAVLTVTVLLVMEGLSAFLHALRLHWVEFQNKFYEGSGYKFTPLSFDSLLK---TEQ-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VE75-1", "uniprot_id": "Q9VE75_DROME", "id": "Q9VE75-1", "name": "V-type proton ATPase subunit a", "aln": "------------MGDMFRSEEMALCQMFIQPEAAYTSVSELGETGCVQFRDLNVNVNAFQRKFVTEVRRCDELERKIRYIETEIKKDGIVLPDIQ--------DDIPRAPNPREIIDLEAHLEKTESEMIELAQNEVNMKSNYLELTELRKVLENTQGFFSD-----------------------QEVLNLDSSNRAGGDNDA---AAQHRGRLGFVAGVINRERVFAFERMLWRISRGNVFLKRSDLDEPLNDPATG---HPIYKTVFVAFFQGEQLKNRIKKVCTGFHASLYPCPSSHNEREEMVRNVRTRLEDLKLVLSQTEDHRSRVLATVSKNLPSWSIMVKKMKAIYHTLN---LFNMDVTKKCLIGECWVPTNDLPVVQKALS------DGSAAVGSTIPSFLNVIDTN--------------------------------EQPPTFNRTNKFTRGFQNLIDAYGVASYRECNPALYTCITFPFLFAVMFGDLGHGLILVLFGAWMVLCERKLARIRN----GGEIWNIFFGGRYIILLMGLFAMYTGLVYNDVFSKSMNLFGSRWFNN-----------------YNTTTVLTN--PNLQLPPNSS--AVGV-YPFGMDPVWQLA-DNKIIFLNSFKMKLSIIFGVLHMVFGVCMSVVNFTHFKRYASIFLEFVPQILFLLLLFGYMVFMMFFKWFSYNARTSFQPETPGCAPSVLIMFINMMLFKN-TEPPKGCNEFMFESQPQLQKAFVLIALCCIPWMLLGKPLYIKFTRKNK--AHANH----------NGQLTGNIELAEGETPLP--TGFSGNEENAGGAHGHDDEPMSEIYIHQAIHTIEYVLSTISHTASYLRLWALSLAHAQLSEVLWQMVLSLGLKMSGVGGA--IGLFIIFGAWCLFTLAILVLMEGLSAFLHTLRLHWVEFMSKFYEGMGYAFQPFSFKAILD---GEEEE-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VE77-1", "uniprot_id": "Q9VE77_DROME", "id": "Q9VE77-1", "name": "V-type proton ATPase subunit a", "aln": "MSKWWSCGSNQESNSIFRSEVMSLVQMYLQPEAAYDTIAALGEVGCVQFRDLNAKINAQQRKFIGEVRRCDELERRIRYVTAELNKEGHKVLDLM--------DDFPPAPQPREIIDLELHLEKTETEILELAANNVNLQTSYLELSEMIQVLERTDQFFSD-----------------------QESHNFD-LNKMGTHRDP---EKSN-GHLGFVAGVISREREYAFERMLWRISRGNVFVRRCDVDVALTDPKTG---NVLHKSVFVVFFQGDQLQARIRKVCTGFHAHMYPCPSSHSERQEMVKNVRTRLEDLQVIINQTSDHRTCVLQAALKQLPTWSAMVKKMKGIYHTLN---LFNVDLGSKCLIGEGWVPKRELELVEVALA------AGSASVGSTVPSFINVLDTK--------------------------------KEPPTHFRTNKFTRGFQNLIDAYGIAGYREVNPGLYTCITFPFLFAVMFGDMGHGTILFLLGLWMVIDEKRLSKKR-----GGEIWNIFFAGRYIIMLMGLFAMYTGFHYNDIFSKSINVFGTRWVNV-----------------YNRTTVLTN--PTLQLNPSVA--TRGV-YPMGIDPIWQSA-SNKIIFLNTYKMKLSIIFGVLHMVFGVCMSVENFVFFKKYAYIILQFVPQVLFLLLMFGYMCFMMFYKWVKYSPTTDVEADTPGCAPSVLIMFIDMVLFKT-ETALPGCDVNMFPIQKNLEMIFLVVALLCIPWILLGKPLYIKYQRRNRPAGPVEE----------VDEIVEKIEVTTGKEIII--TEVAEAHE-SGGHSEEDDEPMSEIWIHQAIHTIEYILSTISHTASYLRLWALSLAHAQLSEVLWTMVLAMGLQMNGYVGA--IGLFFIFAVWEFFTIAIMVMMEGLSAFLHTLRLHWVEFMSKFYVGNGYPFTPFSFKDILI---VVEDD-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKF6-1", "uniprot_id": "Q9VKF6_DROME", "id": "Q9VKF6-1", "name": "V-type proton ATPase subunit a", "aln": "------------MGDMFRSEKMALCQLFIQPEAAYASIAELGEKGCVQFRDLNEEVSAFQRKYVNEVRRCDDMERRLRYVESEMKKDEVKLPVLRP-------EEEPIAPNPREIVDLEAQLEKTDNELREMSANGASLDANFRHMQELKYVLENTEGFFSD-----------------------QEVINLDVNRKLDPEDPANLPGAAQRGQLAFVAGVIKLERFFSFERMLWRISRGNIFLRRADIDGLVADEETG---RPVLKTVFVAFFQGEQLKQRIKKVCTGYHAAVYPCPSSHAERKEMIKDVNVRLEDLKLVLSQSADHRSRVLNSASKHLPRWSIMVRKMKAIYHILN---FFNPDVTGKCLIGEGWVPTNDISTVQDALA------RASKISESSIPAFMNVIETN--------------------------------EMPPTYTRTNKFTNGFQNLVDSYGMASYREVNPALYACITFPFLFAVMFGDLGHGLILLLFASWLIIKEKQLSSIK------EEIFNIFFGGRYIIFLMGIFSIYTGFIYNDVFSKSMNIFGSAWHMN-----------------YTRDVVEDENLKYITLRPNDT--VYKT-YPFGMDPIWQLA-DNKIIFLNTFKMKLSIIVGVIHMIFGVSMSVVNFAYYKKYASIFLEFLPQVLFLLLLFGYMVFMMFFKWVVYN-DTVEGPLSPACAPSILILFINMILQGS-QDTPEPCKEFMFDGQKSIQQVFVVVAIICIPWMLLGKPLYIMIKRKTN-----------------------------GAPPPK--PQSG-----GGEGHGEDDE-MGEIFIHQAIHTIEYVLSTVSHTASYLRLWALSLAHAQLSEVLWNMVFSMGFKYDSYIGG--ILIYVFFGAWALLTVGILVLIEGLSAFLHTLRLHWVEFMSKFYEGAGYAFEPFAFKTILD---VSEDD-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9XZ10-1", "uniprot_id": "Q9XZ10_DROME", "id": "Q9XZ10-1", "name": "V-type proton ATPase subunit a", "aln": "------------MGSLFRSEEMALCQLFLQSEAAYACVSELGELGLVQFRDLNPDVNAFQRKFVNEVRRCDEMERKLRYLEKEIKKDGIPMLDTG---------ESPEAPQPREMIDLEATFEKLENELREVNQNAEALKRNFLELTELKHILRKTQVFFDESVPTVYKSSGAYSSSKYRRYPQMADNQNEDEQAQLLGEEGVRASQPGQNLKLGFVAGVILRERLPAFERMLWRACRGNVFLRQAMIETPLEDPTNG---DQVHKSVFIIFFQGDQLKTRVKKICEGFRATLYPCPEAPADRREMAMGVMTRIEDLNTVLGQTQDHRHRVLVAAAKNLKNWFVKVRKIKAIYHTLN---LFNLDVTQKCLIAECWVPLLDIETIQLALR------RGTERSGSSVPPILNRMQTF--------------------------------ENPPTYNRTNKFTKAFQALIDAYGVASYREMNPAPYTIITFPFLFAVMFGDLGHGAIMALFGLWMIRKEKGLAAQKT----DNEIWNIFFGGRYIIFLMGVFSMYTGLIYNDIFSKSLNIFGSHWHLS-----------------YNKSTVMEN--KFLQLSPKGD--YEGAPYPFGMDPIWQVAGANKIIFHNAYKMKISIIFGVIHMIFGVVMSWHNHTYFRNRISLLYEFIPQLVFLLLLFFYMVLLMFIKWIKFA-ATNDKPYSEACAPSILITFIDMVLFNTPKPPPENCETYMFMGQHFIQVLFVLVAVGCIPVMLLAKPLLIMQARKQAN---------------------VQPIAGATSDAEA--GGVSNSGSHGGGGGHEEEEELSEIFIHQSIHTIEYVLGSVSHTASYLRLWALSLAHAQLAEVLWTMVLSIGLKQEGPVGG--IVLTCVFAFWAILTVGILVLMEGLSAFLHTLRLHWVEFQSKFYKGQGYAFQPFSFDAIIENGAAAAEE-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32563-1", "uniprot_id": "VPP1_YEAST", "id": "P32563-1", "name": "V-type proton ATPase subunit a, vacuolar isoform", "aln": "--------MAEKEEAIFRSAEMALVQFYIPQEISRDSAYTLGQLGLVQFRDLNSKVRAFQRTFVNEIRRLDNVERQYRYFYSLLKKHDIKLYEGDTDKYLDGSGELYVPPSGSVIDDYVRNASYLEERLIQMEDATDQIEVQKNDLEQYRFILQSGDEFFLK----------------------GDNTDSTSYMDEDMIDANGENIAAAIGASVNYVTGVIARDKVATLEQILWRVLRGNLFFKTVEIEQPVYDVKTR---EYKHKNAFIVFSHGDLIIKRIRKIAESLDANLYDVDSSNEGRSQQLAKVNKNLSDLYTVLKTTSTTLESELYAIAKELDSWFQDVTREKAIFEILN---KSNYDTNRKILIAEGWIPRDELATLQARLG------EMIARLGIDVPSIIQVLDTN--------------------------------HTPPTFHRTNKFTAGFQSICDCYGIAQYREINAGLPTIVTFPFMFAIMFGDMGHGFLMTLAALSLVLNEKKINKMK-----RGEIFDMAFTGRYIILLMGVFSMYTGFLYNDIFSKTMTIFKSGWKWP----------------------------DHWKKGESITATSVG-TYPIGLDWAWHGT-ENALLFSNSYKMKLSILMGFIHMTYSYFFSLANHLYFNSMIDIIGNFIPGLLFMQGIFGYLSVCIVYKWAVDWVKDGKP------APGLLNMLINMFLSPGTIDD------ELYPHQAKVQVFLLLMALVCIPWLLLVKPLHFKFTHKKKSHEPLPS-------------TEADASSEDLEAQQLISAMDADDAEEEEVGSGSHGEDFGDIMIHQVIHTIEFCLNCVSHTASYLRLWALSLAHAQLSSVLWTMTIQIAFGFRGFVGV--FMTVALFAMWFALTCAVLVLMEGTSAMLHSLRLHWVESMSKFFVGEGLPYEPFAFEYKDMEVAVASASSSASS", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A1ZBF7-1", "uniprot_id": "A1ZBF7_DROME", "id": "A1ZBF7-1", "name": "V-type proton ATPase subunit a", "aln": "--MRVFKKRQTKVKSFFRSEDMDLCQLLLHTENAFDCLIEVGHHGAVQFNNVYDEDRLLNNLYSKKVTQCYELLRIVDSLHTYIVQLHVNEIFYP-------DVDRENRLKEKDLAKYSDSLKRIHVEASAVTEHYYRLDSRRNRMMEHSFALNKANKYMVS---------------------DMGSELLYSESTVIGLVQDATTTSGAYPAHLNYMIGCIRADKFYSFELLLYRLCSFNLIIRFSEMPSPVYEYHYGYKPERVRKFAILMMASSTMIWPKVLKICAHYHVNIYDCPSSASQREDKVKELSQEIVNVEKVLKEAELMRRQILEVAGRDLFIIRVNLRKALKVYDLMNRLRLVGGVEVPRYLLAEVYIPSSDVPEVEVILRNASRISGGADNIDSSDEDEMNDMKTMPNTTPYPIEADFQPLEDMSAGAILLKKNRLVNHMPPTYFRLNKFTRGFQNLIDAYGMADYKELNPAPYTIITFPFLFAVMFGDLGHGILLILFSSLMIWKHREIEKYQINATSENEILNILYAGRYIILLMGVFSVYMGLVYNIVMAKGFNLFGSSWSCR-----------------YNETTVYDP-AFHVTLDSSHPHFYSGHPYPLGMDPVWAVCGQDSITTTNSLKMKMAIVLGISQMMFGLGLAAANCVLMNRKADLILVVIPQMIFMLCLFGYLVFLIFYKWMSYGGHKPAPYN-AACAPSVLITFINMMLMKKEDPVEN-CLDYMYPNERMIEFALVGIAFCTIPILLAGKPIYLMRRRRKMQQERERD-----------FKRMRRQTIAEMRSTMRYTDDDNSETSRQKSVDNEEEHEMSEIWIHSGIHTIETVLGSVSHTASYLRLWALSLAHDQLSDVLWHMVLTKGFANTLPLYYGVPVLMATFFAWAILTVAILVMMEGLSAFLHTLRLHWVEFQSKFFGGAGESFKAFNFPTSNQRS-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** : * *. : : : . * *:*.:: :. : .: : .: : . : . : . . : : * : : * : : ::* :*:* :: . : :: *: :: . * : . :: :: : * : : :: :* . : ::.* : . : :. * : *** : * ** .** : :.**:. *:* ... : :****:**:**** *** :: . :: *: **:::::**:*::* *: ** ::: .:* : * * .*:* * : : *: ***::::.*. :* :. :. * : :* : *: :* *: . :. ** **.:* :*.* * :: : :: :: : :* :: ..: : .: : . **:** *. :*:************** :*:.*** * : .: : : :* :::::** **:**::****** .**: * * .: * ", "identical_positions": 123, "similar_positions": 177, "identity": "12.6%" }, { "cls_id": "homologset.agr.SGD:S000005797", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63965-1", "uniprot_id": "SFXN1_RAT", "id": "Q63965-1", "name": "Sideroflexin-1", "aln": "------------------MSGEVPPNINIKEPRWDQSTFIGRASHFFTVTDPKNILLTNEQLENARKVVHDYRQG-IVPAGLTENELWRAKYAYDSAFHPDTGEKMTLIGRMSAQVPMNMTITGCMMTFYRTTPAVLFWQWINQSFNAVVNYTNRSGDAPLT-VNELGTAYVSATTGAVATALG-------LNALT--KHVSPLIGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDENGTRLGESTNAAKQAITQVVISRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVTLVGFCLVFATPLCCALFPQKSSMSVTSL---EDDLQASIQKS--HPELRRVYFNKGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JR1-1", "uniprot_id": "SFXN1_MOUSE", "id": "Q99JR1-1", "name": "Sideroflexin-1", "aln": "------------------MSGEVPPNINIKEPRWDQSTFIGRASHFFTVTDPRNILLTNEQLENARKVVHDYRQG-IVPAGLTENELWRAKYAYDSAFHPDTGEKMTLIGRMSAQVPMNMTITGCMMTFYRTTPAVLFWQWINQSFNAVVNYTNRSGDAPLT-VNELGTAYVSATTGAVATALG-------LNALT--KRVSPLIGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDENGTRLGESTNAAKQAITQVVISRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVTLVGFCLVFATPLCCALFPQKSSMSVTSL---EDELQASIQRT--HPEIRRVYFNKGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H9B4-1", "uniprot_id": "SFXN1_HUMAN", "id": "Q9H9B4-1", "name": "Sideroflexin-1", "aln": "------------------MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQG-IVPPGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFWQWINQSFNAVVNYTNRSGDAPLT-VNELGTAYVSATTGAVATALG-------LNALT--KHVSPLIGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESANAAKQAITQVVVSRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLVGFCLVFATPLCCALFPQKSSMSVTSL---EAELQAKIQES--HPELRRVYFNKGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R5W5-1", "uniprot_id": "F1R5W5_DANRE", "id": "F1R5W5-1", "name": "Sidoreflexin", "aln": "------------------MAATISTSINIKEPRWDQGTFVGRAKHFFTVTDPRNILLSNKQLEKAHQIIQDYKKG-VVAADLTEDELWRAKYVFDSAFHPDTGEKMLLIGRMSAQVPMNMTITGCMMTFYRTTPAVLFWQWINQSFNAIVNYTNRSGDAPIT-VNQLGTAYVSATTGAVATALG-------LNALA--KHVSPLIGRFVPFAAVAAANCINIPLMRQRELKHGIPVTDENDNRLGESSKAAQQAITQVVVSRILMASPGMAIPPFLMNSLEKKAFLKRFPWMSAPIQVGLVGFCLVFATPLCCALFPQKSSMAVSRL---EPELQEKIRAS--HPGVETVYFNKGL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q91V61-1", "uniprot_id": "SFXN3_MOUSE", "id": "Q91V61-1", "name": "Sideroflexin-3", "aln": "-------------------MGDLPLNINIQEPRWDQSTFLGRARHFFTVTDPRNLLLSGEQLEASRNIVQNYRAG-VATPGLTEDQLWRAKYVYDSAFHPDTGEKVVLIGRMSAQVPMNMTITGCMLTFYRKTPTVVFWQWVNQSFNAIVNYSNRSGDAPIT-VQQLGTAYVSATTGAVATALG-------LKSLT--KHLPPLVGRFVPFAAVAAANCINIPLMRQRELQVGIPVTDEAGQRLGHSVTAAKQGIFQVVISRIGMAIPAMAIPPVIMNTLEKKDFLKRRPWLGAPLQVGLVGFCLVFATPLCCALFPQRSSIHVTRL---EPELRAQIQAQ--NPSIDVVYYNKGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JHY2-1", "uniprot_id": "SFXN3_RAT", "id": "Q9JHY2-1", "name": "Sideroflexin-3", "aln": "-------------------MGDLPLNINIQEPRWDQSTFLGRARHFFTVTDPRNLLLSGKQLEASRNIVQNYRAG-VVTPGLTEDQLWRAKYVYDSAFHPDTGEKVVLIGRMSAQVPMNMTITGCMLTFYRKTPTMVFWQWVNQSFNAIVNYSNRSGDAPIT-VQQLGTAYVSATTGAVATALG-------LKSLT--KHLPPLVGRFVPFAAVAAANCINIPLMRQRELQVGIPVTDEAGQRLGHSVTAAKQGIFQVVVSRIGMAIPAMAIPPVIMNTLEKKDFLKRRPWLGAPLQVGLVGFCLVFATPLCCALFPQRSSIHVTRL---EPELRAQIQAQ--KPSIDVVYYNKGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BWM7-1", "uniprot_id": "SFXN3_HUMAN", "id": "Q9BWM7-1", "name": "Sideroflexin-3", "aln": "-------------------MGELPLDINIQEPRWDQSTFLGRARHFFTVTDPRNLLLSGAQLEASRNIVQNYRAG-VVTPGITEDQLWRAKYVYDSAFHPDTGEKVVLIGRMSAQVPMNMTITGCMLTFYRKTPTVVFWQWVNQSFNAIVNYSNRSGDTPIT-VRQLGTAYVSATTGAVATALG-------LKSLT--KHLPPLVGRFVPFAAVAAANCINIPLMRQRELQVGIPVADEAGQRLGYSVTAAKQGIFQVVISRICMAIPAMAIPPLIMDTLEKKDFLKRRPWLGAPLQVGLVGFCLVFATPLCCALFPQKSSIHISNL---EPELRAQIHEQ--NPSVEVVYYNKGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VN13-1", "uniprot_id": "SFXN1_DROME", "id": "Q9VN13-1", "name": "Sideroflexin-1-3", "aln": "-------------------MSPLPR-VNIDEPKYDQNSYLGRAKHFFLLTNPLNVLASASKLEEARQIVIKYRAGKDVPECKTIDDVWRAKYLYDSAFHPETGEKQIVIGRMAAQMPMNTIITGGMMAFYKSTPAVVFWQWFNQTFNAIVNYTNRSGTSPIS-QQQLVTSYCLATSGALVTALS-------LNHAV--KNMNPLLGRLVPLVAVGAANCINIPCMRMQELRNGVTLFDEHSNEMGISKKAAVVGISTVILSRIAMAIPGMTLTPVLMNVLEKRGFLAKYPRSNAPIQTLFCGFVLIFATPLGCAFFKQRADIKVDSL---ESEVRDSIRKK--RPELETVWFNKGL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q925N2-1", "uniprot_id": "SFXN2_MOUSE", "id": "Q925N2-1", "name": "Sideroflexin-2", "aln": "-------------------MEGDLSGFNIDAPRWDQCTFLGRVKHFFNITDPRTVFASEQELDWAKAVVEKSRMG-LVPPGTQMEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQVPGGMLITGFMLQFYRTMPAVIFWQWVNQSFNALVNYTNRNAASPTS-VRQMALSYFTATTTAVATAVG-------MNMWT--KRAPPLVGRWVPFAAVAAANCVNIPMMRQQELIQGICVKDRNQNELGHSQRAAAVGIAQVVISRITMAAPGMILLPVIMERLERLHLMKKVKVMHAPLQVLLCGCFLLFMVPVACGLFPQECELSVSYL---EPELRDTIKAK-YGEQVLFVYFNKGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G419-1", "uniprot_id": "A0A8I6G419_RAT", "id": "A0A8I6G419-1", "name": "Sidoreflexin", "aln": "-------------------MEVDLSGFNIDAPRWDQCTFLGRVKHFFNITDPRTVFVSEQELDWAKSVVEKSRMG-LMPPGTQVEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQVPGGMIITGFMLQFYRTMPAVVFWQWVNQSFNALVNYTNRNAVSPTS-VRQMALSYFIATSTAVATAVG-------MNLWT--KRAPPLVGRWVPFAAVAAANCVNIPMMRQQELIQGICVKDRNQNELGHSRRAAAVGITQVVISRITMAAPGMILLPVVMERLERLHLMKKLKVLHAPLQVLLCGCFLLFMVPVACGLFPQECELPVSYL---EPELQNTIKAK-YGEQVLFAYFNKGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96NB2-1", "uniprot_id": "SFXN2_HUMAN", "id": "Q96NB2-1", "name": "Sideroflexin-2", "aln": "-------------------MEADLSGFNIDAPRWDQRTFLGRVKHFLNITDPRTVFVSERELDWAKVMVEKSRMG-VVPPGTQVEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQLPGGMIITGFMLQFYRTMPAVIFWQWVNQSFNALVNYTNRNAASPTS-VRQMALSYFTATTTAVATAVG-------MNMLT--KKAPPLVGRWVPFAAVAAANCVNIPMMRQQELIKGICVKDRNENEIGHSRRAAAIGITQVVISRITMSAPGMILLPVIMERLEKLHFMQKVKVLHAPLQVMLSGCFLIFMVPVACGLFPQKCELPVSYL---EPKLQDTIKAK-YGELEPYVYFNKGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GUY0-1", "uniprot_id": "A0AC58GUY0_DANRE", "id": "A0AC58GUY0-1", "name": "Sidoreflexin", "aln": "----MHEVSCGLRMISRERTMEAVKGFDIDAPRWDQSTFMGRLKHFFNITDCRTALLPDSRLDEAKVLVESCRAG-SVPPGTTEEQLHYAKKLYDSAFHPDTGDRMNLIGRMSFQVPGGMAITGFMLQFYRTVPAVVFWQWVNQSFNALVNYTNRNAASPIT-PKQIGVAYVTATSTALATAVG-------LNLYT--KKAPPLVARWVPFAAVAAANCVNIPMMRQQEILHGIAVTDEDGNKLGHSRKAAVKGITQVVISRVTMAAPGMIILPIIMQRLEKHRFMQKITFLHGPLQVMMVGVFLIFMVPAACSLFPQRCSMAVSKL---EPELRESIISQ-YGEQISHVYFNKGL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVW3-1", "uniprot_id": "SFXN2_DROME", "id": "Q9VVW3-1", "name": "Sideroflexin-2", "aln": "-------------------MSQVSTLIDVDKPLFDLSTFAGRFQYFAWMTDPRTVVVSSDRLLEAKAMVERYRKG-DQSPPLKPEEVHYNMKLYNSAFHPDTGELQNFCGRMSFQVPGGMLITGGMLAFYRTVPAVVLWQFINQSFNAVVNYTNRNANSPTS-VTQLGVAYVSATTSALVAAIGC------KNYWS--KKATPLFQRFVPFAAVAAANFVNIPLMRQNEIINGIEVKNDDGVVVGQSRLAAIKGIGEVVVSRIAMAAPGMLVLPLIMERLEKLPAYRRIKWINAPFQTLLVGCFLCFMVPTACALFPQQCSLDTSIMRTFEPELYEDLEKKTQGKVPKRVYFNKGL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12029-1", "uniprot_id": "FSF1_YEAST", "id": "Q12029-1", "name": "Sideroflexin FSF1", "aln": "------------------MASSVPGPIDLPESRYDLSTYWGRIRHCAEISDPTMLLTTEKDLAHAREIISAYRHG---ELKETTPEFWRAKKQLDSTVHPDTGKTVLLPFRMSSNVLSNLVVTVGMLTPGLGTAGTVFWQWANQSLNVAVNSANANKSHPMS-TSQLLTNYAAAVTASCGVALGLNNLVPRLKNIS--PHSKLILGRLVPFAAVVSAGIVNVFLMRGNEIRKGISVFDSNGDEVGKSKKAAFMAVGETALSRVINATPTMVIPPLILVRLQRGVLKGKSLGVQTLANLGLISVTMFSALPFALGIFPQRQAIHLNKL---EPELHGKKDKD--GKPIEKVYFNRGI", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q925N0-1", "uniprot_id": "SFXN5_MOUSE", "id": "Q925N0-1", "name": "Sideroflexin-5", "aln": "MADTATTASAASAAASAPNASTDAPPFQLGKPRFQQTSFYGRFRHFLDIIDPRTLFVTEKRLREAVQLLEDYKHG-TLRPGVTNEQLWSAQKIKQAILHPDTNEKIFMPFRMSGYIPFGTPIVVGLLLPNQTLASTVFWQWLNQSHNACVNYANRNATKPSP-ASKFIQGYLGAVISAVSIAVGLNVLVQKANKFT--PATRLLVQRFVPFPAVASANICNVVLMRYGELEEGIDVLDADGNLVGSSKIAARHALLETALTRVVLPMPILVLPPIVMSMLEKTALLQARPRLLLPVHSLVCLAAFGLALPLAISLFPQMSEIETSQL---EPEIARATSSR-------TVVYNKGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CFD0-1", "uniprot_id": "SFXN5_RAT", "id": "Q8CFD0-1", "name": "Sideroflexin-5", "aln": "MADTATTASAASAAASASNASSDAPPFQLGKPRFQQTSFYGRFRHFLDIIDPRTLFVTEKRLREAVQLLEDYKHG-TLRPGVTNEQLWSAQKIKQAILHPDTNEKIFMPFRMSGYIPFGTPIVVGLLLPNQTLASTVFWQWLNQSHNACVNYANRNATKPSP-ASKFIQGYLGAVISAVSIAVGLNVLVQKANKFT--PATRLLVQRFVPFPAVASANICNVVLMRYGELEEGIDVLDADGNLVGSSKIAARHALLETALTRVVLPMPILVLPPIVMSMLEKTALLQARPRLLLPVHSLVCLAAFGLALPLAISLFPQMSEIETSQL---EPEIARATSSR-------TVVYNKGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TD22-1", "uniprot_id": "SFXN5_HUMAN", "id": "Q8TD22-1", "name": "Sideroflexin-5", "aln": "MADTATTASAA--AASAASASSDAPPFQLGKPRFQQTSFYGRFRHFLDIIDPRTLFVTERRLREAVQLLEDYKHG-TLRPGVTNEQLWSAQKIKQAILHPDTNEKIFMPFRMSGYIPFGTPIVVGLLLPNQTLASTVFWQWLNQSHNACVNYANRNATKPSP-ASKFIQGYLGAVISAVSIAVGLNVLVQKANKFT--PATRLLIQRFVPFPAVASANICNVVLMRYGELEEGIDVLDSDGNLVGSSKIAARHALLETALTRVVLPMPILVLPPIVMSMLEKTALLQARPRLLLPVQSLVCLAAFGLALPLAISLFPQMSEIETSQL---EPEIAQATSSR-------TVVYNKGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R7K0-1", "uniprot_id": "F1R7K0_DANRE", "id": "F1R7K0-1", "name": "Sidoreflexin", "aln": "MAESAS-----------------CPRFLLGKPRFEQSTFLGRLRHFIDIIDPSTLFVTESRLKECMKLLDDFKRG-NLPAGVTDQQLWEAQKVKQAIIHPDTGEKIFMPFRMSGYVPFGTPIVVGLLLPNQTLASTVFWQWLNQSHNACVNYANRNATKPTP-TSKFIQGYVGAVTSAVSIAVGLNVLIQKSSKFN--PATRLFIQRFIPFPAVASANICNVALMRHNELSEGIDVLDSDGNVVGSSRIAAKHALIETALTRVALPLPIFVLPPIIMAFLEKLPLLQARRRLMLPVHSLVCLLVFGLSLPLAISLFPQMSEIEASHL---EPEIAMATDCK-------VLTYNKGL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1P320-1", "uniprot_id": "A0A8M1P320_DANRE", "id": "A0A8M1P320-1", "name": "Sidoreflexin", "aln": "MPESTE-----------------FPPFRLGESRFDQGSFYGRLRHFLDVIDPRTLFVSGRRLNECMKLLDQFKNG-TLPPGVTNGQLWKAQKIKQAIIHPDTGEKIPMPFRMSGFVPFGTPVVVGLLLPNQTFSSTIFWQWLNQSHNACVNYCNRNATKPTP-ISTFFQGYLGAVSSAVTIAVGLNVLIKRAEHFS--PATRILVQRFIPFPAVASANVCNVLLMRHTELSEGISVLDDKGNVVGTSKLAARHALIETSLTRVVLPMPVLLLPPLVMSLLERLPFLQKRPRVTLPDHSMVCLCAFGLALPVAISLFPQNSQIHVSEL---EPKISAATHCQ-------ILTYNKGL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q925N1-1", "uniprot_id": "SFXN4_MOUSE", "id": "Q925N1-1", "name": "Sideroflexin-4", "aln": "------------------------MEPNLQFWISERQAFFRRFCQWMDLLDPVNMFISIGSIEKSRQLLFT--TEDAPKHYLDNQVIKDAWNKSLSTVHPDSSKLIPHLFRPAAFLPVTAPMVFLLMMPDTGIKSIILTQGCLYGYTTAFNITNGNASYSHG---PVERTLLGAGVSVSSTFIGLIPHLFQMKY----PPNNFWLKRTLPIVFLAQVSGMNVFASRSFENHRGIEVMDKEGHVVGHSRKAGRKAIKDTAKSRAVLFGTSALAPELFIHIFKRTRFYPQTLLSLVILRMSSTFFMMGLMVPVSFSMFPQIGQIQCSQL---EEKIQSSTEEK-------ELFYYRGV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G785-1", "uniprot_id": "A0A8I6G785_RAT", "id": "A0A8I6G785-1", "name": "", "aln": "------------------------------------MSFFRRFCQWMDLLDPVNVFISVESIEKSRQLLFT--TEDAPKHYLDNQRVKDAWNKSLSTVHPDSSKLIPHLFRPAAFLPVTAPMVLLMMMPDTGIKSIILTQGCLYGYTTAFNITNGNASYSHG---PVERTLLGAGVFASSTFFGSIPHLFQLKY----PLNNLWLKRFLPIIFLAQISGMNVFASRSFENHRGIEVMDKEGHVIGYSRKAGRKAIKETAKSRAVLFGTSALAPELFIHIFKRTRFYPQTLLASVILRMSSTLFMMGLMVPVSFSMFPQIGQIQCSQL---EEMIRSSTEEK-------ELFYYRGV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P4A7-1", "uniprot_id": "SFXN4_HUMAN", "id": "Q6P4A7-1", "name": "Sideroflexin-4", "aln": "MSLEQEEETQPGRLLGRRDAVPAFIEPNVRFWITERQSFIRRFLQWTELLDPTNVFISVESIENSRQLLCT--NEDVSSPASADQRIQEAWKRSLATVHPDSSNLIPKLFRPAAFLPFMAPTVFLSMTPLKGIKSVILPQVFLCAYMAAFNSINGNRSYTCK---PLERSLLMAGAVASSTFLGVIPQFVQMKY----GLTGPWIKRLLPVIFLVQASGMNVYMSRSLESIKGIAVMDKEGNVLGHSRIAGTKAVRETLASRIVLFGTSALIPEVFTYFFKRTQYFRKNPGSLWILKLSCTVLAMGLMVPFSFSIFPQIGQIQYCSL---EEKIQSPTEET-------EIFYHRGV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8E7G5-1", "uniprot_id": "SFXN4_DANRE", "id": "A8E7G5-1", "name": "Sideroflexin-4", "aln": "------------------------MDPNLQYWQNNGQSFLSRLGLWSKILDPT-LLLSQAEIEEARTLIQN--EENTPG---KNDKVSNAWLLSLSSVHSDTGAVISPAYRPQVFLPISAPLVVGSLIAHKGIKSAMFWQFVLHTYCAGFNHANRNATATKDNKTTMKQSLLILGAVSYSTVTGALPQIILQRLRLISSLTQTICRSFLPVPLAAGLAAFNILVVRSEEAENGISLFDANGNAVGVSKEAGFKAVKETAISRATLFGTTAALPTFLMALLERAKFVQRNPRLIAPIGSMCTVITFGLMIPVSFSLFPQLGKIKKENL---EKEFQSLDGNE-------ELFYHRGL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * : : . . : . :: . : .*.::. * : . : :: * . .* * . . . . :*. *: * * *: : : :* * *. .: . :* . .. ::: : * .:* * : : * . : :*:", "identical_positions": 20, "similar_positions": 55, "identity": "5.62%" }, { "cls_id": "homologset.agr.SGD:S000005798", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61480-1", "uniprot_id": "WDR12_RAT", "id": "P61480-1", "name": "Ribosome biogenesis protein WDR12", "aln": "------MAQLQARFYTENKK--YAVDDVPFSIPATSEVADLSNIINKLLETKNELHKHVEFDFLIKGQFLRMPLVKHMELEDISSEEVVELEYVEKYTAPQPEQCMFHDDWISSIKG--AEEWILSGSYDKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLTASMDQTILLWEWN-------------------IERNKVKALHCCRGHAGSVDAIAVDSSGTKFCSGSWDKMLKIWSTVP------------TDEEDEIQEPTNRPRKKQKTEQLGLTRTPLVTLSGHTEAISSVLWSDADEVC--SASWDHTVRVWDVESGGLKSTLTGNKVFNCISYSPLCKRLASGSTDRHIRLWDPRT-KDGSLVSLSLTSHTGWVTSVKWSPTHDQQLISGSLDNMVKLWDTRSCKAPLYDLAAH--------EDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJA4-1", "uniprot_id": "WDR12_MOUSE", "id": "Q9JJA4-1", "name": "Ribosome biogenesis protein WDR12", "aln": "------MAQLQARFYSENKK--YAVDDVPFSIPAAAEVADLSNIINKLLETKNELHKHVEFDFLIKGQFLRVPLVKHMELENISSEEVVELEYVEKYTAPQPEQCMFHDDWISSIEG--AEEWILSGSYDKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLTASMDQTVLLWEWN-------------------VEKNKVKALHCCRGHAGSVDAIAVDSSGAKFCSGSWDKMLKIWSTVP------------TDEEDEMEEATNRPRKKQKTEQLGLTRTPLVTLSGHTEAISSVLWSDAEEIC--SASWDHTIRVWDVESGGLKSTLTGNKVFNCISYSPLCKRLASGSTDRHIRLWDPRT-KDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLWDTRSCKAPLYDLAAH--------EDKVLSVDWTDTGLLLSGGADNKLYSYSYSPTTSHVGA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZL7-1", "uniprot_id": "WDR12_HUMAN", "id": "Q9GZL7-1", "name": "Ribosome biogenesis protein WDR12", "aln": "------MAQLQTRFYTDNKK--YAVDDVPFSIPAASEIADLSNIINKLLKDKNEFHKHVEFDFLIKGQFLRMPLDKHMEMENISSEEVVEIEYVEKYTAPQPEQCMFHDDWISSIKG--AEEWILTGSYDKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWN-------------------VERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVP------------TDEEDEMEESTNRPRKKQKTEQLGLTRTPIVTLSGHMEAVSSVLWSDAEEIC--SASWDHTIRVWDVESGSLKSTLTGNKVFNCISYSPLCKRLASGSTDRHIRLWDPRT-KDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLWDTRSCKAPLYDLAAH--------EDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NX08-1", "uniprot_id": "WDR12_DANRE", "id": "Q6NX08-1", "name": "Ribosome biogenesis protein wdr12", "aln": "------MSQLQARFFTENKK--YLVDDVPFSIPASSEVADLSGVINKLLEAKNAGHKHVEFDFLVRGQFLRTSLDKHIETENISTEEVVEIEYVEKFTAPQPEECIMHDDWISSVEA--DSEWILTGSYDKTARIWSMEGKAVMTVAGHADVVKDVAWVKRDGLNSVLLTASLDQTVMLWEWN-------------------SERNKVKARHCCRGHAGSVDTIAVDPTRTKFCSGSWDKMLKIWSAVP------------TEEEDEIEEP-NRPRKKQKTEQMGLTRTPLMTLSGHNEAVSSVLWMDADELC--SASWDHTIRLWDAETGGQKSTLSGSKVFNCISYSPLCRRLASGSTDRHVRLWDPRS-KDGSLVLLSLTSHNGWVTAVRWAPSHEHQLVSGSLDNVVKLWDTRSCKAPLYDLAAH--------EDKVLCADWTENGLILSGGADNKLYTYRYAACVSDAGA--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKQ3-1", "uniprot_id": "WDR12_DROME", "id": "Q9VKQ3-1", "name": "Ribosome biogenesis protein WDR12 homolog", "aln": "MDVDNGEGQVQVHLKTKQEH--YAVPDVPYAIDGTVTTVELNTFVNALLRQKD-GSSDTDFDFLVFDEYLRGRLCDHLREKAISFEDAIEIEYVERFPAPEPQDCLLHDDWVSAVKA--RGKWILSGCYDNTLNLWTNKGKHILTISGHTAPIKAVDWISLDEETGRFVSTSQDQTAMLWQWN-------------------VGSNSVECVSVCKGHERGVDSVSVSPDGLRFATGSWDTMLKVWS---------------AELDDAVEGSSKRMKESG-------VRTPKITLQGHRESVSAVQWMDATTLL--TGSWDHTLKVWDLSLEGIKTEISTNKSIFDASYSKLNRLILTASADKNLRLYDPRT-NQGSVVRNTYLGHNAWVQTVMWSTTEEFLFVSGAYDNQNKLWDCRSPKAPLYDLLGH--------GEKVLDIDWSNPKYIVSGGVDNTVRVFKSRKALAEEAETK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12024-1", "uniprot_id": "YTM1_YEAST", "id": "Q12024-1", "name": "Ribosome biogenesis protein YTM1", "aln": "--MTEDKSQVKIRFFTREKDELLHVQDTPMYAPISLKRYGLSEIVNHLLGSEK----PVPFDFLIEGELLRTSLHDYLTKKGLSSEASLNVEYTRAILPPSYLNSFSNEDWVSSLDVGDGSKHIISGSYDGIVRTWDLSGNVQKQYSGHSGPIRAVKYIS----NTRLVSAGNDRTLRLWKTKNDDLKLTSQQQAQEDDDDEVNIEDGKTLAILEGHKAPVVSIDVS-DNSRILSASYDNSIGFWSTIYKEMTVVDPLEDINNPNNKISTAARKRRKLTMKDGTIRRRAPLSLLESHTAPVEQVIFDSTDNTVGYSVSQDHTIKTWDLVTARCIDTRTTSYSLLSIAQLSTLNLLACGSSARHITLHDPRVGASSKVTQQQLIGHKNFVSSLDTCPENEYILCSGSHDGTVKVWDVRS-TSPMYTITREDKSVQKGVNDKVFAVKWAEKVGIISAGQDKKIQINKGDNIFKN-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*:: :: : ::. * *.* : *. .:* ** :. . ****: .: ** * .:: : :* * :::**.. .*. :.: ::**:*::. : *::*.** . * .*: **: :: * ::. . ::::. *:* **: : :. : .** * :: *. :: :.*:*. : .** : :: :. . .: :: *:* *..* .:. * : .: : * ***:: ** : . : : . : .*: ::: * *** ...:. .*. :* :: .. .: : **: *. *:** ** .:*:* : . :**: .*:: ::*.* *:.: . ", "identical_positions": 78, "similar_positions": 146, "identity": "16.35%" }, { "cls_id": "homologset.agr.SGD:S000005799", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NYN7-1", "uniprot_id": "S22A6_DANRE", "id": "Q6NYN7-1", "name": "Solute carrier family 22 member 6", "aln": "-MAFSDLLEQVGSTGRFQVLHVTLLSMPILMMASHNLLQNFVAAVPPHHCQPHANLSMSS-TDAVDVLRATVPLGLNGKLERCKRYTTPQWQILSLNTSESLWDESMAETETQSCEDGWFYNMTEMSSTIITEWDLVCDYRALKQMSQTTYMGGVLVGAIVFGGLSDRFGRRVLLLISNLMMAIGGTCVAFST-SFTMFCVFRVCCGMALSGLVLNSFSLIVEWIPTRVRTVVGTG-TGYCYT--TGQLILAAVAYCIRDWRWLTLAVSLPFYVSFLYSWWFLESARWLVLTKNPEQAVKNLKTVARINGRSAEGDKIDLEMLQESMKKEMACSKGSYSALDLLRTSTMRTITICLSAVWFSTSFAYYGLS-MDLQKFGVSIYLIQIIFGAVD-------IPAKIIVTICMSMLGRRPS--------------------------QCGALVLAGIMILINLLVPSDLQMLRTSLAVIGKGCLAASFNCCYLYAGELYPTVIRQSGMGWVSMMARFGAMVAP-----------------MVLLLGDDYPWIPGFIYGG---------------------------APIVSGIFAFFLPETLS--------QPLPDTIQDIDDRGLARTNSK--RLPEKLDLAMKDPSCVLLKESV---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6YVM2-1", "uniprot_id": "A0A8M6YVM2_DANRE", "id": "A0A8M6YVM2-1", "name": "", "aln": "MIDFTQILSSVGEFGAFQKRLLVAVCLPNIFTAFHMFGQVFTAISFPHYCNSSWILRQAPNLTEEKQLNLTVPLDSKGQYESCKMFTPVEMDIEDI--------EHYGINTTTSCIDGWVYKAPKDSSTLITEFDLVCENKVYSEASQSIYMAGLLVGALLFGPMADKYGRRFATLLSLFLQFLSGVGVAFSP-NIYVYIALRFVVGTTISGISINTFVLGTEWCGSAKRALFTIL-SHCFFA--IGLMLLSGVAYGIRNWRVLQLVLSAPVGLFFIYYWILPESARWLLTQGKLDSAKREILKAARINGRKVS------ENLLDKMEAENTAK--SSTMIDLFRVGYLRKRALIMCYMWFVTSLVYYGVS-LNVGNFGLDIYLTQLIFGMAE-------FPARLSCFPLIQRFGRRIC--------------------------QSVVLLLGGTACLIIPAIPAKYPIVVTVIAVIGKFSLAASFSIVYVYTAELYPTVVRQNGVGLNSMCARVAGILAP-----------------LIGLLDVYHHAIPMIIYGS---------------------------LPFVGGALTFLLPETLN--------TDLQDHTDIPADESMTVTEVKLERWGRRRGWDRERSTSQDFKSGRL--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PJE3-1", "uniprot_id": "A0A8M9PJE3_DANRE", "id": "A0A8M9PJE3-1", "name": "", "aln": "MGNYDEDTAFLGQTGPFFIRLFCLLNLIYISTGLHGLYIVFVAASPAHRCRVDVNLTEDWLEASAPTETLSNGDLQVSQCWRYSLQTLTNLSGQGYSPGQ----INITDIPRERCEDGWVYSADVYHSTIVSEWDLVCDSEWRVPLASSTLYMGYLLGSIVSGQLSDRFGRKKVLFGSLAAEALLMFAQSFSP-SWLIFCVLYFFIGAFQISLYITAFVLGNEVLSGSLRVLFTTLGAFLHYC--VGYMLLPWVAFAIRHWRTLLRVLSGLTVVYIPLWWLIPESPRWLLSQGHVQESEAILRDAARKNRVPAP-----EVIFKQSQIKEAAFQKSKYSALDVLRTSNIRRTTFMCLLLWMAINIGYFGLS-LNTTNLSGDPFLNCFLSAVTE-------VPAYIVSTFLLKSCPRRPV--------------------------LSAFLVIGGGFLLLVQLIPDRLQTLALALEMAGKFGFTMSFTVVYIYTAELYPTVLRNLGMGMCSSAARIGSITAP-----------------YIIFLGTFNRHLPYVLMGS---------------------------LTITASLANLFLPETFG--------KVLPENLEQMQKSRSFP--------GRDKQSVEDGGGGEKMREEKL--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12256-1", "uniprot_id": "TPO4_YEAST", "id": "Q12256-1", "name": "Polyamine transporter 4", "aln": "MPSSLTKTESNSDPRTNIQQVPKALDKNVTNSGNLDSTSSSTGSITEDEKRSEPNADSNNMTGGEPIDPRDLDWDGPDDPDNPHNWSSLKK--------------WYTTMTSAFLCLVVTMGSSLYVSSVPELVERYHVSQTLALAGLTFYLLG--LSTVIGAPLSEVFGRKPVYLFSLPVSMLFTMGVGLSNGHMRIILPLRFLSGVFASPALSVGSGTILDIFDVDQVSVAMTYFVLSPFLGPVLSPIMAGFATEAKGWRWSEWIQLIAGGLILPFIALMPETHKGIILRKRAKKRNIALKKFSREAQKEFLKTTVTITILRPLKMLVVEPIVFVFSVYVAFIFAILFGFFEAYAVIYRGVYHMSMGISGLPFIGIGVGLWIGAFFYLYIDRKYLFPKPPAGTQPLTEKERTSKRTTPYRGARDAETGELLPVVPEKFLIACKFGSVALPIGLFWQAWTARSDVHWMAPVAAGVPFGFGLILIFFSVLMYFSTCYPPLTVASCLAANNLLRYVMSSVFPLFTIQMYTKMKIKWASTLFALVCVVMIPIPWVFEKWGSKLRHKSQFGYAAMEKEAETEGGIDDVNAVDGELNLTRMTTLRTMETDPSTREKPGERLSLRRTHTQPVPASFDREDGQHAQNRNEPISNSLYSAIKDNEDGYSYTEMATDASARMV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : . .. . . .. : : *:: : . . : * :.::: . ::: :**: : * : .:* : : . * : : : ::. .* : ** : : : *: : :: . .. : :* : : : . : :: *:* : :. . :: :: : ** . :* : * . : : * :* . **.: :. . . . * . :: :* .: . . : *: . : . ", "identical_positions": 25, "similar_positions": 101, "identity": "3.7%" }, { "cls_id": "homologset.agr.SGD:S000005800", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A175-1", "uniprot_id": "D4A175_RAT", "id": "D4A175-1", "name": "tRNA dimethylallyltransferase", "aln": "MAAAAAARAVPVSSGFRGLPRTLPLVVILGATGTGKSTLALQLGQRLGGEIVSADSMQVYEGLDIITNKVSAQEQKMCRHHMISFVDPLVTSYTVVDFRNRATALISLRKLSTHPWRVPSGDIFARDKIPIVVGGTNYYIESLLWKVLVTTKP---QGMGTGKAVDRKVELEKEDGHELHKRLSQVDPEMAAKLHPHDKRKVARSLQVFEETGVSHSEFLHRQHAEEGGGPLGGPLKFPNPCILWLHADQA--DERLDKRVDDMLAAGLLEELRDFHRRYNLKNVSEDSQDYQHGIFQSIGFKEFHEYLTTEGKCTPE-------------------------TSNQLLKKGVEALKQVTKRYARKQNRWVRNRFLSRPGPSVPPVYGLEVSDVSKWEEFVLEPALSIVQSFIQGSKPTATPVKIPYSE--TENKRSYHMCDLCDRIIIGDREWAAHTKSKSHLHQLKKRRKLDLDAVSALGSQSNSPDSELERKEGESSGQ-----RDQELKASV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80UN9-1", "uniprot_id": "MOD5_MOUSE", "id": "Q80UN9-1", "name": "tRNA dimethylallyltransferase", "aln": "MAAAAAARAVPVSSGFRGLRRTLPLVVILGATGTGKSTLALQLGQRLGGEIVSADSMQVYEGLDIITNKVSAQEQKMCQHHMISFVDPLVTSYTVVDFRNKATALI--------------EDIFARDKIPIVVGGTNYYIESLLWKVLITTKP---QEMGTGKVVDRKVELEKEDGHELHKRLSQVDPEMAAKLHPHDKRKVARSLQVFEETGISHSEFLHRQHAEEGGGPLGGPLRFPNPCILWLHADQAVLDERLDKRVDDMLAAGLLEELRGFHRRYNLKNISENSQDYQHGIFQSIGFKEFHEYLTTEGKCTPE-------------------------TSNQLLKKGIEALKQVTKRYARKQNRWVKNRFLSRPGPSVPPVYGLEVSDVSKWEESVLEPALNIVQSFIQGHKPTAMPVKMAYNE--SENKRSYHMCDLCDRIIIGDREWAAHLKSKSHLHQLKKRRRLDLDAVSATGSQSNSPDCDPERIEGESSGQ-----HNQELKASV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H3H1-1", "uniprot_id": "MOD5_HUMAN", "id": "Q9H3H1-1", "name": "tRNA dimethylallyltransferase", "aln": "MASVAAARAVPVGSGLRGLQRTLPLVVILGATGTGKSTLALQLGQRLGGEIVSADSMQVYEGLDIITNKVSAQEQRICRHHMISFVDPLVTNYTVVDFRNRATALI--------------EDIFARDKIPIVVGGTNYYIESLLWKVLVNTKP---QEMGTEKVIDRKVELEKEDGLVLHKRLSQVDPEMAAKLHPHDKRKVARSLQVFEETGISHSEFLHRQHTEEGGGPLGGPLKFSNPCILWLHADQAVLDERLDKRVDDMLAAGLLEELRDFHRRYNQKNVSENSQDYQHGIFQSIGFKEFHEYLITEGKCTLE-------------------------TSNQLLKKGIEALKQVTKRYARKQNRWVKNRFLSRPGPIVPPVYGLEVSDVSKWEESVLEPALEIVQSFIQGHKPTATPIKMPYNE--AENKRSYHLCDLCDRIIIGDREWAAHIKSKSHLNQLKKRRRLDSDAVNTIESQSVSPDHNKEPKEKGSPGQ-----NDQELKCSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LWL7-1", "uniprot_id": "Q1LWL7_DANRE", "id": "Q1LWL7-1", "name": "tRNA dimethylallyltransferase", "aln": "--MAAATRVLQKG-------IKPSLVVILGATGTGKSKLAIEIGKRLNGEIISADSMQVYKGLDIITNKVTEEEQAQCHHHMISFVDPLVSGYTVVDFRNKALSLI--------------EDMHHRKKLPVIVGGTNYYIESILWKVLIDTGQGSDTEPEKGGGADSRAGLEKLGGPELHRRLKEVDPDMAAILHPHDSRKIARSLQVYMDTGVPHSRLLEEQRGQDGGDCLGGPLRFQDPCIFWLNGKTNVLDERLDKRVDQMLSLGLIDELKDFHLRFNEKMIKESSQNYQHGIFQSIGFKEFHEYLTTSENISQE-------------------------ERDKLMNKGIESLKQVTRRYARKQNKWVRNRFLKRPASNVPPVYGLDVTDVTNWETTVLTPALEILDCLQKGEQPSAQPIKAEGVE--SRNKRSHHMCDLCEKVIIGDLEWTAHQKSKNHLYQVRKKRKSEQ-------------ATDLDTKHAKHQND-----CDKQVPAL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IMV0-1", "uniprot_id": "Q8IMV0_DROME", "id": "Q8IMV0-1", "name": "C2H2-type domain-containing protein", "aln": "------------------MIRKVPLIVVLGSTGTGKTKLSLQLAERFGGEIISADSMQVYTHLDIATAKATKEEQSRARHHLLDVATPAEP-FTVTHFRNAALPIV--------------ERLLAKDTSPIVVGGTNYYIESLLWDILVDSDVKP-DEGKHSGEHLKDAELNALSTLELHQHLAKIDAGSANRIHPNNRRKIIRAIEVYQSTGQTLSQMLAEQRAQPGGNRLGGPLRYPHIVLLWLRCQQDVLNERLDSRVDGMLAQGLLPELRQFHNAHHATTV----QAYTSGVLQTIGYKEFIPYLIKYDQQQDEKIEEYLKTHSYKLPGPEKLKEEGLPDGLELLRNCCEELKLVTRRYSKKQLKWINNRFLASKDRQVPDLYELDTSDVSAWQVAVYKRAETIIESYRNEEACEILPMAKREHPGADLDEETSHFCQICERHFVGEYQWGLHMKSNKHKRRKEGQRKRQRDHETMLSTDLAKKQKEEKEEAGKAETQPPPSRVNDTDKAM-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07884-1", "uniprot_id": "MOD5_YEAST", "id": "P07884-1", "name": "tRNA dimethylallyltransferase", "aln": "---------MLKGPLKGCLNMSKKVIVIAGTTGVGKSQLSIQLAQKFNGEVINSDSMQVYKDIPIITNKHPLQEREGIPHHVMNHVDWSEEYYSHR-FETECMNAI--------------EDIHRRGKIPIVVGGTHYYLQTLFNKRVDTKSS------ERKLTRKQLDILESTDPDVIYNTLVKCDPDIATKYHPNDYRRVQRMLEIYYKTGKKPSETFNEQKIT---------LKFDT-LFLWLYSKPEPLFQRLDDRVDDMLERGALQEIKQLYEYYSQNKFTP--EQCENGVWQVIGFKEFLPWLTGKTD-----------------------------DNTVKLEDCIERMKTRTRQYAKRQVKWIKKMLIPDIKG---DIYLLDATDLSQWDTNASQRAIAISNDFISNRPIKQERAPKALEELLSKGETTMKKLDDWTHYTCNVCRNADGKNVVAIGEKYWKIHLGSRRHKSNLKRNTRQADFEKWKINKKETVE--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::*: *:**.**: *::::.:::.**::.:****** : * * * . :*: **::. . :: *.. . : : : . *::****:**::::: . : . *: . ::. * : *. * **:: *:: * :::: .** *. : .*: *:: ::** . :***.*** ** * : *:: :: . . . : *: * **:*** :* . :.. * :* *::*:::* :*:.: :: :* *:.:*:: *: . * * : . .: : : : : . . : : : . : : ", "identical_positions": 74, "similar_positions": 127, "identity": "14.34%" }, { "cls_id": "homologset.agr.SGD:S000005801", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WU78-1", "uniprot_id": "PDC6I_MOUSE", "id": "Q9WU78-1", "name": "Programmed cell death 6-interacting protein", "aln": "MASFIWVQLKKTSEVDLAKPLVKFIQQTY-PSGGEEQAQYCRAAEELSKLRRSALGRPLDKHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEKSCVLFNCAALASQIAAEQNLDNDEGLKTAAKQYQFASGAFLHIKDTVLSALSREPTVDISPDTVGTLSLIMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPK-----EVFPTLAAKQCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKNVASRYDEYVNVKDFSDKINRALTAAKKDNDFIYHDRVPDLKDLDPIGKATLVKPTPVNVPVSQKFTDLFEKMVPVSVQQSLAVFSQRKADLVNRSIAQ-MREATTLANGVLASLNLPAAIEDVSGDT-VPQSILTKSTSVVEQGGIQTVDQLIKELPELLQRNREILEESLRLLDEEEATDNDLRAKFKDR-WQRTPSNDLYKPLRAEGAKFRAVLDKAVQADGQVKERYQSHRDTIALLCKPEPELNAAIPSANPAKTMQGSEVVSVLKSLLSNLDEIKKERESLENDLKSVNFDMTSKFLTALAQDGVINEEALSVTELDRIYGGLTSKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSIPPPAYQS---SPAAGHAAAPPTPAPRTMPPAKPQPPARPPPPVLPANRVPPASAAAAPAGVGTASAAPPQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGP--QQPTYPFPQPP--QQSYYPQQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QZA2-1", "uniprot_id": "PDC6I_RAT", "id": "Q9QZA2-1", "name": "Programmed cell death 6-interacting protein", "aln": "MASFIWVQLKKTSEVDLAKPLVKFIQQTY-PSGGEEQAQYCRAAEELSKLRRSALGRPLDKHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEKSCVLFNCAALASQIAAEQNLDNDEGLKTAAKQYQFASGAFLHIKDTVLSALSREPTVDISPDTVGTLSLIMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDALPKYFYFQEVFPTLAAKQCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKNVASRYDEYVNVKDFSDKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKPTPVNVPISQKFTDLFEKMVPVSVQQSLAVFSQRKADLVNRSIAQ-MREATTLANGVLASLNLPAAIEDVSGDT-VPQSILTKSTAVVEQGGIQTVDQLIKELPELLQRNREILEESLRLLDEEEATDNDLRAKFKDR-WQRTPSNDLYKPLRAEGAKFRAVLDKAVQADGQVKERYQSHRDTIALLCKPEPELNAAIPSANPAKTMQGSEVVNVLKSLLSNLDEIKKEREGLENDLKSVNFDMTSKFLTALAQDGVINEEALSVTELDRIYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNSEASLREEVLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSIPPPAYQS---SPAGGHATAP-TPAPRTMPPAKPQPPARPPPPVLPANRVPPAAAATAPAGVGTASAAPPQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYTYGQYNMPYPPVYHQSPGQAPYPGP--QQPTYPFPQPP--QQSYYPQQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WUM4-1", "uniprot_id": "PDC6I_HUMAN", "id": "Q8WUM4-1", "name": "Programmed cell death 6-interacting protein", "aln": "MATFISVQLKKTSEVDLAKPLVKFIQQTY-PSGGEEQAQYCRAAEELSKLRRAAVGRPLDKHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEKSCVLFNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDISPDTVGTLSLIMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPK-----EVFPVLAAKHCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKTVASRYDEYVNVKDFSDKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKFTDLFEKMVPVSVQQSLAAYNQRKADLVNRSIAQ-MREATTLANGVLASLNLPAAIEDVSGDT-VPQSILTKSRSVIEQGGIQTVDQLIKELPELLQRNREILDESLRLLDEEEATDNDLRAKFKER-WQRTPSNELYKPLRAEGTNFRTVLDKAVQADGQVKECYQSHRDTIVLLCKPEPELNAAIPSANPAKTMQGSEVVNVLKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLTALAQDGVINEEALSVTELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSIPTPAYQS---SPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAP-SATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGP--QQPSYPFPQPP--QQSYYPQQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B6D5-1", "uniprot_id": "A0A8M2B6D5_DANRE", "id": "A0A8M2B6D5-1", "name": "Programmed cell death 6-interacting protein", "aln": "MATFISVPLKKSSEVDLVKPLSKFVTATY-PPG-EEQAEYLRAVDELNKLRKSALGRPLDKHESSLEILLRYYDQLCAIEPKFPFP--ELCLTFTWKDAFDKGSLFGGSVKLALASLGYEKTCVLFNVGALASQIASEQNLDNDEGLKTAAKFYQLASGAFAHIKDTVLSALNREPTMDISPETVGTLSQIMLSQAQEVFVLKATSDKMKDAIVAKLANQAADYYGDAFKQCQYKENLPKYFYFQDVLPVLAAKHCMMQATAEMHQSALANQKKKFGEEIARLQHAQELVKTAASRYDEYVNVKDLSDKINRALTAAKKDNDFIYHDRVPEVKDLEHIGKASLVKATAVQTPLSQKFTDLFEKMVPMAVQQSVSAANSRKAETVNRLIGS-MREATNLCNGVLASLNLPAALEDLSGDA-VPQSILEKSRALIQQGGLQSIEQLIKDLPELLQRNREILDESLKMLDDEEATDNELRGKFNQR-WNRTPSGDLYKPLRAEGNNFRNILDKAVQADQVVRERYTAHCEMIALLCKPENELSAAIPSANPAKTLQGSEVVNVLRSQLAQLDEVKREREVLEGEVKSVTFDLTAKFLTALAQDGAINEEVMTSSELDARYGSHNQRVQQNLRRQEELLSQIQVSHQEFSALKQSNSEANTREDVLKKLASAHDSYIEISSNIKEGTKFYNDLTEILLKFQNKCSDIVFARKTERDELLKELQQSIAREPSAPSFSVPSYQSNTPAPAGGPTPAPRTVFSQQQPQAKPQPPARPPPPSIAPQAASAAVPVSAPMAPGSSNPPPVAPTG---PSQAQGPPYPSYQGYPGYYQMPM--AYNPYAYGQYNMPYMP--YQAQGQAGYPGAPATQQPYPYPQQPPQQQPYYPQQ-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VB05-1", "uniprot_id": "Q9VB05_DROME", "id": "Q9VB05-1", "name": "", "aln": "MSKFLGVPLKKPSEVDVIKPLNNLIQSTYNGASEEEKGKYGEAVNEFSKQRNTAIWKFFEKYEASLEIVYAYYDQICALETKISVS--ELQIPFKWKDAFDKGSIFGGKISLTHTSLLYEKVCVLFNIAALQSNIAANQSLDSDDGLKLTIKLLQQSAGIFQYLKGATPAAVPSEPTPDLSQDTLTVLQALMVAQAQEVFILKAIKDNLKDQIIAKLCCQAEESYADVLRAMQ-KESVRS-LWEKEWIPTIAGKQAGFHALTQLYQSLVCRAAKKIGEEIARLRNAIDLFKAAQTRSGNETYLDEYFSRAKRNLTESTKDNEFIYNEIIPELSTLTSPGKAQLAKPLPIAVPLAENFKDIFSSLVPVELHRALTASDMRRNEIVNVEIMK-LREATQTLNAVLASLNLPAAVETADGNSGLPPSLKEKANEVRQKGGIENVQTMLKDLPELLNRNREILDETERLLDEERDSDNQLRAQFKDR-WTRISSDKLTEMFRTNAKKYREVITNAIEADKVVRQKFEANQKGIQLLSLPPDQIQQSLPSASGSVDPNCS-SVQRLKKLMDDVETIKAEREAIESELKGATFNMKDEFLIALQKDGAIDEPALSLARIGQVLNPLQQQVRESVERQQSLVSEIQSAHGAF--VSETGSCGSSRDTLYQELATAFDSYIELSGNLQEGTKFYNDLTQLLVVFQNKISDFVFARKTEKEELLKDLTTESSRQACPATPALPSHYA---STSGSGSDIP-----------------------------PGSAPSVPPAASTANIPYPAQVQGMPIPYGAQ----PGVP-YPAYVPAPMPQSFNPYAT----LPYPG-NYQYQGFPQGPPP-GHYGTYPGSYAN--QQGGYPNQKPPGW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12033-1", "uniprot_id": "PALA_YEAST", "id": "Q12033-1", "name": "pH-response regulator protein palA/RIM20", "aln": "MSELLAIPLKRTLEVDFATELSKLIDTTS----FQTASFFQSDILKVVDARNNAIAP--DISIDGLSALKEYYVILLQLEKKFPNN----QIEFTWFQTLSQK-----SRGTSQYSLQWEKLTIIYNIGCMYSLLALNSNNDAAESLKTSCLYFQNAAGCFKHVLDHQK---NLETIPVVDDATLNALTSLMLAQAQECFWFKAVQDKHKDSLIAKLSQQIVDFYCEAINDAQRGKLIRS-----DWINHLKAKKAYFSAVTYYRIALSFNEKKQFGNVVKALQMGLQFINESTLSS-----QAKFKTVVESSLKEAQRDNEFIYLQEVPSELPSIKPALMVKPSSSATLLPSIKKDETLFKDLIPIEVMEYCTAYNERQDEYVEQRVTNPLASLNKLLKESLTTFQIPQGLTKVSEAE------------------LSHYQASLNNLLINNKNVQVQLDNIEQILNEEAFTDNQLRLKHGTLNWTLPESSTTNTAYYEKLKKLRGYLDEGSAIDKQTNELFQS-------IDKNLIGSEIRLPESNDPLTNKIKMIIQERNDYIDRTRRKSSEYRILPKIITSYKKNGTVDFEPIFIG---------HLKYFDEDLRYVNSTKEENIKLIEEVNLSKKNNPGRSGIEPKKMVRIDPRELYIEDLRYSFKLLDEVKENLSAGTAFYENLITSTSNLYNEVQEYDTARRAEKARLDKSLTFEDQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :: : **:. ***. . * ::: * : . : :. . *. *: : .*. : ** : :* *:. : *.* :::.: . : ** :** :::* ..: * :* :.. * :.** : * ::* * :: *. :. *: .* :*::**** * :** *: ** ::***. * : : :.:. * . : . : : : .*:. : * : : . *::*: : *: . ::.: . : * : :**:*** : :*. . .. . * :: :*..::*: : . :. . *: : *: : . : . . : *:::::* .: . :. : :::* :. : *:: ::*::* :**:** :. * *. : : * : :. * ..: : : : . :*.:. . : . :. .. : . * . : :.. . : . .* : :. .:.:. : : . : :. . *: :.* :.. *: *:. ** **::* : *: .: **::*: .* *.* . ", "identical_positions": 99, "similar_positions": 228, "identity": "11.12%" }, { "cls_id": "homologset.agr.SGD:S000005804", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIF2-1", "uniprot_id": "Q5XIF2_RAT", "id": "Q5XIF2-1", "name": "Uroporphyrinogen-III synthase", "aln": "---MKVLLLKDAKDDDSGQDPYIQELRLCGLEATLIPVLSFEFMSLPSLSEKLSHPEGFGG----LIFTSPRAVEAVKLCLEKDNKTEAWEKSLKDRWNAKSVYVVGSATASLGEESQKDEVNKIGLDAEGAGSGNAEKLAEYICS--KPSSELPLLFPCGTIKGDTLPKMLRDKGIPMESMHVYQTIPHPGIQGSLESYYENQG----IPASITFFSPSGLKYSLEYIQALSGGSFDQIKFVAIGPSTTRAMAAKGLPVSCTAESPTPQALAAGIRKALKPNSCC--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51163-1", "uniprot_id": "HEM4_MOUSE", "id": "P51163-1", "name": "Uroporphyrinogen-III synthase", "aln": "---MKVLLLKDAKEDDSGLDPYIQELRLCGLEATLIPVLSFEFMSLPSLSEKLSHPEGFGG----LIFTSPRAVEAVKLCLEKDNKTEAWEKSLKDRWNAKSVYVVGSATASL--------VNKIGLDAEGAGSGNAEKLAEYICS--KPSSELPLLFPCGTIKGDTLPKMLKDKGIPMESMHVYQTVPHPGIQGSLKSYYEDQG----IPASITFFSPSGLKYSLEYIQALSGSSFDQIKFIAIGPSTTRAMAAKGLPVSCTAESPTPQALAAGIRNVLKPNHCC--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10746-1", "uniprot_id": "HEM4_HUMAN", "id": "P10746-1", "name": "Uroporphyrinogen-III synthase", "aln": "---MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGG----LIFTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASL--------VSKIGLDTEGETCGNAEKLAEYICS--RESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNLNSYYSQQG----VPASITFFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARALAAQGLPVSCTAESPTPQALATGIRKALQPHGCC--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3B3-1", "uniprot_id": "Q9W3B3_DROME", "id": "Q9W3B3-1", "name": "Uroporphyrinogen-III synthase", "aln": "-MTSRQRTVIIFKSESESSDVYAETLEKHDFNPVFVPTLSFGFKNLDELRAKLQNPDKYAG----IIFTSPRCVEAVAESLNLG--------ELPGGWKMLHNYAVGEVTHNLA------LSTLDQLFTHGKQTGNARALGDYIVDTFDGSRALPLLLPCGNLATDTLLSKLAENGFSVDACEVYETRCHPELGANVERALEIYGE---SIEFLAFFSPSGVNCAQQYFTSRQ-LSMDKWKLVAIGPSTRRALESLGQKVYCTAERPTVEHLVKVLLNPQDSRERLLKERERMAAIENNN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VF38-1", "uniprot_id": "Q9VF38_DROME", "id": "Q9VF38-1", "name": "Uroporphyrinogen-III synthase", "aln": "-MGDRNKQPVILLKVPSSDDFYGSALRSHNLDPIFITPSHFVFKNLKQLQAKLHEPHKYAG----IIFASPRCVQAVNEALGKT--------PLPSCWRALHNYSLGKNTHSAA------WITFQNLPTLGDHAVNANNLCDLIVETFGPKRDLPLLMPCGNGVGQTLRLRLVAQGFRVDACEVYESRSHPDFVNQMRHALKFK-----RMETIVFFGPSSVRSSLEFFGNYN-VSLKDRKLIAVGSGTRKAMEESGIKADGVVNAADVDRLINIIKT----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06174-1", "uniprot_id": "HEM4_YEAST", "id": "P06174-1", "name": "Uroporphyrinogen-III synthase", "aln": "MSSRKKVRVLLLKNKTVPIDKYELECRSKAFEPIFVPLIKHTHV-IQDFRNVLNTIPNYLNTINYIIITSQRTVESLNEAIIPTLTS-----EQKAALLSKTVYTVGPATANFIRRS--GFINVKGGEDAGNGSILADIIIDDLSTDIKACPPSELLFLVGEIRRDIIPKKLHSKGIKVREVVTYKTEELSDGFKRFIHAMKECDEDEVFSDWVVVFSPQGTKEITQYLGDSNRLPGSHLRVASIGPTTKKYLDDNDVTSDVVSPKPDPKSLLDAIELYQRHK-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * * ::. ::. . . : .: * : . :*::* * *:: .: * :* * . . * * : : : **: * : : * :*: : .*:: . . . :..*.*.. :.: . .. :. ::*. * : : . . . . * : ", "identical_positions": 23, "similar_positions": 64, "identity": "7.67%" }, { "cls_id": "homologset.agr.SGD:S000005806", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8WZ82-1", "uniprot_id": "OVCA2_HUMAN", "id": "Q8WZ82-1", "name": "Esterase OVCA2", "aln": "------------------------MAAQRPLRVLCLAGFRQSERGFREKTGALRKALRGR-AELVCLSGPHPVPDPPGPE-GARSDFGSCPP-EEQPRGWWFSEQEADVFSALEEPAVCRGLEESLGMVAQALNRLGPFDGLLGFSQGAALAALVCALG----QAGDPRFPLPRFILLVSGFCPRGIGFKESILQRPLSLPSLHVFGDTDKVIPSQESVQLASQFPG--AITLTHSGGHFIPAAAPQRQAYLKFLD-QFAE---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D7E3-1", "uniprot_id": "OVCA2_MOUSE", "id": "Q9D7E3-1", "name": "Esterase OVCA2", "aln": "------------------------MAARQTLRVLCLAGFRQSERGFREKTGALRKTLRGR-AELVCLSGPHPVPEAAAPE-GSCPDSGPCSP-EEQPRGWWFSEEEADVFSALEESTVCRGLQEALETVARALDTLGPFDGLLGFSQGAALAAYVCALG----QAGDPRFPLPRFIILVSGFCPR--GLKEPILQSPMSLPSLHVFGDTDRVIPSQESMQLASRFLG--AVTLTHSGGHFIPAAASQRQAYLKFLD-QFAE---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q503Y4-1", "uniprot_id": "OVCA2_DANRE", "id": "Q503Y4-1", "name": "Esterase OVCA2", "aln": "------------------------MSA-VPLRILCIHGYRQNGNSFREKTGALRKLLKKQ-VELVFISAPHQVPAIQEENCGTNQQSQTVSVGDEDQRGWWFSDVQARSFNAKQDCESSLGLEESIEAVKAALKDLGPFSGILGFSQGAALVAMLCALQE---QKLEPDFNF-RFAILVAGFRSACLEHQRFYEGPVITIPSLHVFGQDDRVIPEEMSRDLLPAFDG--AQVLLHPGGHFVPAASSHRQTYQDFLK-RFQ----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDL1-1", "uniprot_id": "LOVG_DROME", "id": "Q9VDL1-1", "name": "Esterase CG5412", "aln": "MTNNDAAVEAAGSSRASSSKQQLKLEITEKVRVLCLHGYRQNGEAFKNKLGSFRKFANKY-AEFVFITAPHVAKALESAA-------EPVPE----QRSWWANK-DDGSFKGTNKGGPAFGFQESLRCVEEAWRTQGPFQGLLGFSQGACFVGLICGLAK---KKLTS--IRPEFAVLASGFLSGSLVHMSAYEEA-ISIPTLHIYGQTDEIIPKEMSESLAARFKN--AEVLEHSGGHYFPATAQQKQTFINFFQDRLQEYLEHEELQQSGNASFVDSGAEDDNDAEVAAMTAELDESD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99369-1", "uniprot_id": "FSH3_YEAST", "id": "Q99369-1", "name": "Family of serine hydrolases 3", "aln": "--------------------------MSEKKKVLMLHGFVQSDKIFSAKTGGLRKNLKKLGYDLYYPCAPHSIDKKALFQ---SESEKGRDAAKEFNTSATSDEVYGWFFRNPESFNSFQIDQKVFNYLRNYVLENGPFDGVIGFSQGAGLGGYLVTDFNRILNLTDEQQPALKFFISFSGFKLEDQSYQKEYHRI-IQVPSLHVRGELDEVVAESRIMALYESWPDNKRTLLVHPGAHFVPNSKPFVSQVCNWIQGITSKEGQEHNAQPEVDRKQFDKPQLEDDLLDMIDSLGKL----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* : *: *. . * * *.:** . :: .** . .. * :. :: : : ***.*::****** : . : : .* : :** : :*:**: *: *.::... * : . * *.*.*:.* : . .::. ", "identical_positions": 35, "similar_positions": 54, "identity": "11.67%" }, { "cls_id": "homologset.agr.SGD:S000005807", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q78Y63-1", "uniprot_id": "PDCL2_MOUSE", "id": "Q78Y63-1", "name": "Phosducin-like protein 2", "aln": "---------MQDPNEDTEWNEILRNFGILPPKE---EPKDE----------IEEMVLRLQQEAMVKPYEKMTLAQLKEAEDEFDEEDIKAIEIYREKRLQEWKALKKKQKFGELREISGNQYVNEVTNAEKD------------------LWVVIHLYRSSVPMCLVVNQHLSVLARKFPETKFVKAIVNSCIEHYHDNCLPTIFVYKNGQIEGKFIGIIECGGINLKLEELEWKLSEVGAIQS------------------DLEENPKKGIADMMVSSIRNISIYD-SDSSGSDTEAK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6B5E6-1", "uniprot_id": "A0A8I6B5E6_RAT", "id": "A0A8I6B5E6-1", "name": "", "aln": "---------MQDPNEDTEWNEILRNFGILPPKE---EPKDE----------IEEMVLRLQEEAMVKPYEKMTLAQLKEAEDEFDEEDIKAIEIYREKRLQEWKALTKKQKFGELREISGNQYVNEVTNAEKD------------------LWVIIHLYRSSVPMCLVVNQHLSVLARKFPETKFVKAIVNSCIEHYHDNCLPTIFVYKNGQIEGKFIGVIECGGINLKLEELEWKLSQVGAIQT------------------DLEENPKKGIADMMVSSIRNVSIYD-SDSSGSDAEAK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N4E4-1", "uniprot_id": "PDCL2_HUMAN", "id": "Q8N4E4-1", "name": "Phosducin-like protein 2", "aln": "---------MQDPNEDTEWNDILRDFGILPPKE---ESKDE----------IEEMVLRLQKEAMVKPFEKMTLAQLKEAEDEFDEEDMQAVETYRKKRLQEWKALKKKQKFGELREISGNQYVNEVTNAEED------------------VWVIIHLYRSSIPMCLLVNQHLSLLARKFPETKFVKAIVNSCIQHYHDNCLPTIFVYKNGQIEAKFIGIIECGGINLKLEELEWKLAEVGAIQT------------------DLEENPRKDMVDMMVSSIRNTSIHDDSDSSNSDNDTK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BVF2-1", "uniprot_id": "PDCL3_MOUSE", "id": "Q8BVF2-1", "name": "Phosducin-like protein 3", "aln": "---------MQDPNADTEWNDILRKKGILPPKESLKELEEE----------EAEKEEQLLQQSVVKTYEDMTLEELEENEDEFSEEDERAIEMYRQQRLAEWKATQLKNKFGEVLEISGKDYVQEVTKAGEG------------------LWVILHLYKQGIPLCSLINHHLSGLARKFPDVKFIKAISTTCIPNYPDRNLPTVFVYREGDIKAQFIGPLVFGGMNLTIDELEWKLSESGAIKT------------------ALEENPKKPIQDLLLSSVRGPVPMRRDS--DSEDD----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KLJ8-1", "uniprot_id": "PDCL3_RAT", "id": "Q4KLJ8-1", "name": "Phosducin-like protein 3", "aln": "---------MQDPNADTEWNDILRKKGILPPKESLKELEEE----------EEGKEEQRLQQSVVKTYEDMTLEELQENEDEFSEEDERAIEMYRQQRLAEWKATQLRNKFGEVLEISGKDYVQEVTKAGEG------------------LWVVLHLYKQGIPLCSLINHHLSGLARKFPDVKFIKAISTTCIPNYPDRNLPTVFVYREGDIKAQFIGPLVFGGMNLTIDELEWKLSESGAIKT------------------ELEENPKKAIKDVLLSSVRDPVPMRRDS--DSEDD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H2J4-1", "uniprot_id": "PDCL3_HUMAN", "id": "Q9H2J4-1", "name": "Phosducin-like protein 3", "aln": "---------MQDPNADTEWNDILRKKGILPPKESLKELEEE----------AEE-EQRILQQSVVKTYEDMTLEELEDHEDEFNEEDERAIEMYRRRRLAEWKATKLKNKFGEVLEISGKDYVQEVTKAGEG------------------LWVILHLYKQGIPLCALINQHLSGLARKFPDVKFIKAISTTCIPNYPDRNLPTIFVYLEGDIKAQFIGPLVFGGMNLTRDELEWKLSESGAIMT------------------DLEENPKKPIEDVLLSSVRRSVLMKRDS--DSEGD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P268-1", "uniprot_id": "PDCL3_DANRE", "id": "Q6P268-1", "name": "Phosducin-like protein 3", "aln": "---------MQDPNADTEWNDILRKKGILPPKE--TPVEEE----------EDE-QLHLQSQSVVKTYEDMTLEELEENEDEFSEEDEHAMEMYRLKRLAEWKANQMKNVFGELKEISGQDYVQEVNKAGEG------------------IWVVLHLYKQGIPLCSLINQHLAQLARKFPQSKFLKSISSTCIPNYPDRNLPTLFVYRDGEMKAQFIGPLVFGGMNLTCDELEWRLSESGAVKT------------------DLEENPRKQIQDQLMTSIRCSANTHRDGEEDSDED----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MR62-1", "uniprot_id": "PHLP2_DROME", "id": "Q8MR62-1", "name": "Phosducin-like protein 2", "aln": "---------MQDPNEDTEWNDVLRAKGIIGPKAKEAEITEDQIQKLMDDAIQRRTDLPLNEGQRDKKIDDMSLDELDELED---SEDEAVLEQYRQRRIAEMRATAEKARFGSVREISGQDYVNEVTKAGEG------------------IWVVLHLYANGVPLCALIHHHMQQLAVRFPQTKFVRSVATTCIPNFPEKNLPTIFIYHEGALRKQYIGPLELRGDKLTAEELEFMLGQAGAVPT------------------EITEDPRPQIRDKMLADLEDK---------SSDFY----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12017-1", "uniprot_id": "PLP2_YEAST", "id": "Q12017-1", "name": "Phosducin-like protein 2", "aln": "MQNEPMFQVQVDESEDSEWNDILRAKGVIPERAP--SPTAK----------LEEALEEAIAKQHENRLEDKDLSDLEELED---DEDEDFLEAYKIKRLNEIRKLQERSKFGEVFHINKPEYNKEVTLASQGKKYEGAQTNDNGEEDDGGVYVFVHLSLQSKLQSRILSHLFQSAACKFREIKFVEIPANRAIENYPESNCPTLIVYYRGEVIKNMITLLELGGNNSKMEDFEDFMVKVGAVAEGDNRLIMNRDDEESREERKLHYGEKKSIRSGIRGKFNVGIGGNDDGNINDDDDGFFD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . *:***::** *:: : . : :. * :*.: ** .** :* *: :*: * : : **.: .*. :* :**. * :. ::*.:** .. . :: : : * :* : **:. . .* :: : **:::* * : : * : * : . :::* : : **: : . : : . : ... ..: ", "identical_positions": 42, "similar_positions": 76, "identity": "13.95%" }, { "cls_id": "homologset.agr.SGD:S000005809", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K8S8-1", "uniprot_id": "A0A0G2K8S8_RAT", "id": "A0A0G2K8S8-1", "name": "Fructose-2,6-bisphosphatase TIGAR", "aln": "-------------MPRFALTIIRHGETRLNKEKIIQGQGVDAPLSETGFRQAAATGQFLSN--VHFTHAFSSDLTRTKQTIHGILEKSRFCKDIAVKYDSRLRERMYGVAEGKPLSELRAMAKAAGEECPMFTPPGGETVEQVKMRGKDFFDFICQLILGKAGQRENFLPGAPDNCLESSLAEVFPVGKHGSLGTDPKHGALGLTASILVVSHGAYMRSLFGYFLSDLRCSLPATIDKFELSSITPNTGISVFIID--CEEAR--KPTVQCVCMNLQEHLNKGVEKH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQ88-1", "uniprot_id": "TIGAR_HUMAN", "id": "Q9NQ88-1", "name": "Fructose-2,6-bisphosphatase TIGAR", "aln": "-------------MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNN--VKFTHAFSSDLMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSLFIIN--FEEGREVKPTVQCICMNLQDHLNGLTETR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q29RA5-1", "uniprot_id": "TIGRA_DANRE", "id": "Q29RA5-1", "name": "Probable fructose-2,6-bisphosphatase TIGAR A", "aln": "-------------MLAFGLTVVRHGETQCNKDGLLQGQKIDSLLSDIGIQQSEAAGQYLRD--VKFTNVFVSNMKRAKQTAEIIVRNNRTCHDLELVADPSLIERSFGIAEGGRVIDMKNMAKAAGQPLPEFTPPEGETMEQVKLRIKDFLKAMYQRIAN--DHQDKVQDGGTSSADESTEA---PAGLAN-------DGVSSVPVHALVVGHGAYMSIAMRYFFEDLKCPVPRGLDPAQQFSICPNTGMCRFIITLKCSSVDIALSDIKCVFINRRDHFKTN----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12040-1", "uniprot_id": "YO283_YEAST", "id": "Q12040-1", "name": "Broad-specificity phosphatase YOR283W", "aln": "MTKEVPYYCDNDDNNIIRLFIIRHGQTEHNVKKILQG-HKDTSINPTGEEQATKLGHYLRSRGIHFDKVVSSDLKRCRQTTALVLKHSKQ-ENVPTSYTSGLRERYMGVIEGMQITEAEKYADKHGEGS----------FRNFGEKSDDFVARLTG-------------------CVEEEVAEASNEGVKN----------------LALVSHGGAIRMILQWLKYENHQAHKIIVFNTSVTIVDYVKDSKQFIVR--RVGNTQHLGDGEFVVSDLRLR--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ::***:*. * . ::** * :. * .*: * :* . ::* :.. *:: * :** ::...: .:: . * ** *: ** : : . *. : . :. : **. : . * * * :*.**. : : :: : : . : . : .. **: : : : : : ", "identical_positions": 35, "similar_positions": 66, "identity": "12.2%" }, { "cls_id": "homologset.agr.SGD:S000005811", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NFU3-1", "uniprot_id": "TSTD1_HUMAN", "id": "Q8NFU3-1", "name": "Thiosulfate:glutathione sulfurtransferase", "aln": "------------------------------------MAG--------------------------APTVSLPELRSLLASGR--ARLFDVRSREEA-AAGTIPGALNIPVSELESALQMEPAAFQALYSAEKPKLEDEHLVFFCQMGKRGLQATQLARSLGYTGARNYAGAYREWLEKES-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LEJ3-1", "uniprot_id": "A0ABK0LEJ3_RAT", "id": "A0ABK0LEJ3-1", "name": "Rhodanese domain-containing protein", "aln": "------MEVPENPWDVRVRCLQVPWGGLFVERGAWGVAAGLKQPGRGVQRQVSCPPALKSFFSFPVPTVSFSELRQLLASGR--ARLFDVRSREEA-AAGTIPGALNIPVSELEMALNMDPAAFQTSYCAEKPKLEDKNLIFFCQMGRRGLQATQLAQGLGYTGARNYAGAYKEWLEKEG-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PY03-1", "uniprot_id": "E9PY03_MOUSE", "id": "E9PY03-1", "name": "", "aln": "--------------MLRLAVLRHSH----TSAAAGTMAG--------------------------VPTVSFSELRSLVASGR--ARLFDVRSPEEA-AAGTIPGALNIPVSELEIALNMDPAAFQTLYCAEKPKLEDKNLIFFCQMGRRGLQATQLAQGLGYTGARNYAGAYKEWLEKQG-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B8A5G0-1", "uniprot_id": "B8A5G0_DANRE", "id": "B8A5G0-1", "name": "", "aln": "-------------------------------MAS------------------------------SDNDISYSDLKSILAKGS--AVLVDVRTNEEV-ARGTIPGSIHIPVGNIGQDLSLDAAEFQSKFGVGKPPLDCTELVFFCQLGRRGAAATEKAKSLGFKNARNYAGAYKEWSEKEGK------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12305-1", "uniprot_id": "RDL1_YEAST", "id": "Q12305-1", "name": "Thiosulfate:glutathione sulfurtransferase", "aln": "------------------MWKAVMNAWNGTESQSKNVSN--------------------------IQSYSFEDMKRIVGKHDPNVVLVDVREPSEY-SIVHIPASINVPYRSHPDAFALDPLEFEKQIGIPKPDS-AKELIFYCASGKRGGEAQKVASSHGYSNTSLYPGSMNDWVSHGGDKLDL--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A8M1PUV1-1", "uniprot_id": "A0A8M1PUV1_DANRE", "id": "A0A8M1PUV1-1", "name": "", "aln": "MVSFQILRRLGVFALTKPVCHGRILSACGIKTSNINHSHGQPG---------------------AVSVVTYEQLKGMLANHS--VQLFDVRNPDEF-QAGRIPDSVNVPLGELEVSLKLPAEKFEEQFKVKAPQKADDNIVFHCRSGKRSLTALETAHRLGFSKARHYAGGYIDWEEREKN------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22978-1", "uniprot_id": "CG445_DROME", "id": "P22978-1", "name": "Rhodanese domain-containing protein CG4456", "aln": "-------------------------------------------------------------------MATYEQVKDVPNHPD--VYLIDVRRKEELQQTGFIPASINIPLDELDKALNLDGSAFKNKYGRSKPEK-QSPIIFTCRSGNRVLEAEKIAKSQGYSNVVIYKGSWNEWAQKEGL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCD9-1", "uniprot_id": "Q9VCD9_DROME", "id": "Q9VCD9-1", "name": "Rhodanese domain-containing protein", "aln": "------MMMRHCMMALRVARSQIPFSTARNTQSNLLQRFYSQAP--------------------QIGIVDYDVVKKLPSEPQ--KLLIDVREPEELKETGQIPASINIPLGVVSQELAASEQLFKSKYGREKPKP-ETEIIFHCKIGKRSLKAAEAAAALGFKNVKNYQGSWLDWAEREGLPK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG33-1", "uniprot_id": "Q9VG33_DROME", "id": "Q9VG33-1", "name": "Sulfurtransferase", "aln": "-------------------------------------------------------------------MATYEEVKDIPNHPE--KYLFDVRNESELKETGVLPASINIPLSELEKALNLPEEDFAQTYGRVKPAV-DAVLIFSCKAGGRAARAANLASTLGFTNAKAYAGSWTEWQAKQS-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "G3V8W9-1", "uniprot_id": "G3V8W9_RAT", "id": "G3V8W9-1", "name": "", "aln": "--MLARLVLGTSCRAVLGSVEPALGGLKSRWGSSQHFCSTLS------------------------KDVTYRELKNLLNSKD--IMLIDVRNTWEILEHGKIPGSVNIPLDEVGEALQMNPREFKEKYGEEKPSK-SDRLVFSCLAGVRSKKAMDTAISLGFNSAQHYIGGWTEWVTYEISEKKQS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0B5-1", "uniprot_id": "TSTD3_MOUSE", "id": "Q9D0B5-1", "name": "Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3", "aln": "--MLARLVLGTSGRAALGSVEPALGGLKSIWRCSQAFCSTP-------------------------KGVTYRELKSLLNSKD--IMLIDVRNTLEILEQGKIPGSINIPLDEVGEALQMNPVDFKEKYCQVKPSK-SDRLVFSCLAGVRSKKAMDTAISLGFNSAQHYAGGWKEWVTYEISEEKQES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "H0UI37-1", "uniprot_id": "TSTD3_HUMAN", "id": "H0UI37-1", "name": "Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3", "aln": "------MKIEKCGWS---------EGLTSIKGNCHNFYTAIS------------------------KDVTYKELKNLLNSKN--IMLIDVREIWEILEYQKIPESINVPLDEVGEALQMNPRDFKEKYNEVKPSK-SDS------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : *.*** * :* ::::* : * * ", "identical_positions": 9, "similar_positions": 10, "identity": "4.81%" }, { "cls_id": "homologset.agr.SGD:S000005812", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NFU3-1", "uniprot_id": "TSTD1_HUMAN", "id": "Q8NFU3-1", "name": "Thiosulfate:glutathione sulfurtransferase", "aln": "--------------------------------MAG--------------------------APTVSLPELRSLLASG--RARLFDVRSREEAAAG-TIPGALNIPVSELESALQMEPAAFQALYSAEKPKLEDEHLVFFCQMGKRGLQATQLARSLGYTGARNYAGAYREWLEKES-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LEJ3-1", "uniprot_id": "A0ABK0LEJ3_RAT", "id": "A0ABK0LEJ3-1", "name": "Rhodanese domain-containing protein", "aln": "--MEVPENPWDVRVRCLQVPWGGLFVERGAWGVAAGLKQPGRGVQRQVSCPPALKSFFSFPVPTVSFSELRQLLASG--RARLFDVRSREEAAAG-TIPGALNIPVSELEMALNMDPAAFQTSYCAEKPKLEDKNLIFFCQMGRRGLQATQLAQGLGYTGARNYAGAYKEWLEKEG-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PY03-1", "uniprot_id": "E9PY03_MOUSE", "id": "E9PY03-1", "name": "", "aln": "----------MLRLAVLRHSH----TSAAAGTMAG--------------------------VPTVSFSELRSLVASG--RARLFDVRSPEEAAAG-TIPGALNIPVSELEIALNMDPAAFQTLYCAEKPKLEDKNLIFFCQMGRRGLQATQLAQGLGYTGARNYAGAYKEWLEKQG-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B8A5G0-1", "uniprot_id": "B8A5G0_DANRE", "id": "B8A5G0-1", "name": "", "aln": "---------------------------MAS------------------------------SDNDISYSDLKSILAKG--SAVLVDVRTNEEVARG-TIPGSIHIPVGNIGQDLSLDAAEFQSKFGVGKPPLDCTELVFFCQLGRRGAAATEKAKSLGFKNARNYAGAYKEWSEKEGK------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1PUV1-1", "uniprot_id": "A0A8M1PUV1_DANRE", "id": "A0A8M1PUV1-1", "name": "", "aln": "--MVSFQILRRLGVFALTKPVCHGRILSACGIKTSNIN---------------HSHGQPGAVSVVTYEQLKGMLANH--SVQLFDVRNPDEFQAG-RIPDSVNVPLGELEVSLKLPAEKFEEQFKVKAPQKADDNIVFHCRSGKRSLTALETAHRLGFSKARHYAGGYIDWEEREKN------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22978-1", "uniprot_id": "CG445_DROME", "id": "P22978-1", "name": "Rhodanese domain-containing protein CG4456", "aln": "---------------------------------------------------------------MATYEQVKDVPNHP--DVYLIDVRRKEELQQTGFIPASINIPLDELDKALNLDGSAFKNKYGRSKPEKQ-SPIIFTCRSGNRVLEAEKIAKSQGYSNVVIYKGSWNEWAQKEGL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCD9-1", "uniprot_id": "Q9VCD9_DROME", "id": "Q9VCD9-1", "name": "Rhodanese domain-containing protein", "aln": "MMMRHCMMALRVARSQIPFSTARNTQSNLLQRFYS----------------------QAPQIGIVDYDVVKKLPSEP--QKLLIDVREPEELKETGQIPASINIPLGVVSQELAASEQLFKSKYGREKPKPE-TEIIFHCKIGKRSLKAAEAAAALGFKNVKNYQGSWLDWAEREGLPK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG33-1", "uniprot_id": "Q9VG33_DROME", "id": "Q9VG33-1", "name": "Sulfurtransferase", "aln": "---------------------------------------------------------------MATYEEVKDIPNHP--EKYLFDVRNESELKETGVLPASINIPLSELEKALNLPEEDFAQTYGRVKPAVD-AVLIFSCKAGGRAARAANLASTLGFTNAKAYAGSWTEWQAKQS-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08742-1", "uniprot_id": "RDL2_YEAST", "id": "Q08742-1", "name": "Thiosulfate sulfurtransferase RDL2, mitochondrial", "aln": "--------MFKHSTGILSRTVSARSPTLVLRTFTT----------------------KAP--KIYTFDQVRNLVEHPNDKKLLVDVREPKEVKDY-KMPTTINIPVNSAPGALGLPEKEFHKVFQFAKPPHD-KELIFLCAKGVRAKTAEELARSYGYENTGIYPGSITEWLAKGGADVKPKK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "G3V8W9-1", "uniprot_id": "G3V8W9_RAT", "id": "G3V8W9-1", "name": "", "aln": "--MLARLVLGTSCRAVLGSVEPALGGLKSRWGSSQ--------------------HFCSTLSKDVTYRELKNLLNSK--DIMLIDVRNTWEILEHGKIPGSVNIPLDEVGEALQMNPREFKEKYGEEKPSKS-DRLVFSCLAGVRSKKAMDTAISLGFNSAQHYIGGWTEWVTYEISEKKQS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0B5-1", "uniprot_id": "TSTD3_MOUSE", "id": "Q9D0B5-1", "name": "Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3", "aln": "--MLARLVLGTSGRAALGSVEPALGGLKSIWRCSQ--------------------AFCSTP-KGVTYRELKSLLNSK--DIMLIDVRNTLEILEQGKIPGSINIPLDEVGEALQMNPVDFKEKYCQVKPSKS-DRLVFSCLAGVRSKKAMDTAISLGFNSAQHYAGGWKEWVTYEISEEKQES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "H0UI37-1", "uniprot_id": "TSTD3_HUMAN", "id": "H0UI37-1", "name": "Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3", "aln": "------MKIEKCGWS---------EGLTSIKGNCH--------------------NFYTAISKDVTYKELKNLLNSK--NIMLIDVREIWEILEYQKIPESINVPLDEVGEALQMNPRDFKEKYNEVKPSKS-DS------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : *.*** * :* ::::*:. * * : * ", "identical_positions": 10, "similar_positions": 12, "identity": "5.46%" }, { "cls_id": "homologset.agr.SGD:S000005813", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZDJ5-1", "uniprot_id": "D3ZDJ5_RAT", "id": "D3ZDJ5-1", "name": "rRNA biogenesis protein RRP36", "aln": "------------------------------------------------------MR----KEGCNAKARADGP-----------------HRATKGG----DAIGDRPKADTSDMSFEELLRLQSQVKPKTSKQLVAGNNTKTQS---PRQPACVSDKHRPLEMSAKVPVPFL---RQVVPISKKVA---RDPRFDDLSG-EYNPEVFDKTYQFLNDIRAKEKQLVKRQLK--KHRSGEKHEKLQQLLQRMEQQEMAQQERKQQQELRLALKQERRALAQQGHRPYFLKKSEQRQLALAEKFKDLKRSKKLESFLSRKRRRNAGKDRRHLPLSKEH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UFY0-1", "uniprot_id": "RRP36_MOUSE", "id": "Q3UFY0-1", "name": "Ribosomal RNA processing protein 36 homolog", "aln": "------------------------------------------------------MR----KAGSRARAEAEGP-----------------HRAMEGG----EVTGDRLKADTPDVSFEELLRLQGQGRPKAHKQLVAGNSTRTRS---PQQPVCVADKHRPLEMSAKVRVPFL---RQVVPISKKVA---RDPRFDDLSG-DYNPEVFDKTYQFLNDIRAKEKQLVKKQLK--RHRSGEERDKLQQLLQRMEQQEMAQQERKQQQELRLALKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKELRRSKKLESFLSRKRRRNAGKDRRHLPLSKE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EU6-1", "uniprot_id": "RRP36_HUMAN", "id": "Q96EU6-1", "name": "Ribosomal RNA processing protein 36 homolog", "aln": "------------------------------------------------------MPGANYRAGAGAGAGARRPRGAR-------------DREEDGGGLEPAAVARDLLRGTSNMSFEELLELQSQVGTKTYKQLVAGNSPKKQASRPPIQNACVADKHRPLEMSAKIRVPFL---RQVVPISKKVA---RDPRFDDLSG-EYNPEVFDKTYQFLNDIRAKEKELVKKQLK--KHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRRHLPLSKE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1L876-1", "uniprot_id": "Q1L876_DANRE", "id": "Q1L876-1", "name": "rRNA biogenesis protein RRP36", "aln": "MDKKLNKMPKSTKRAAKLEPQSSDDEEDELEMERNFALLSKKRMNQAPAEDEEDMR----DEGESAEEEDEAPEEVEEDDAASDEDESDSEHEDEGNSKTQSHMEGNIKKELSTMSFEEIMALQNKVGTKVYNKIAYGDTKQKKK----NEPMKRLNKHRPQEISSKQRVPFL---RKVVPVKKMIS---RDPRFDDLSG-EYKPEIFNQTYKFIKNIQEKEAQEVRKQLK--KTKSKAKQEELKALLRRMDNQQRARQRQEQEREKELEFKRKQRELVGQGHKPFYLKKSDKKKLELAEKYSELKKSGKLENFLSKKRKRNATKDRRKLPSKHKTR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFJ1-1", "uniprot_id": "Q9VFJ1_DROME", "id": "Q9VFJ1-1", "name": "rRNA biogenesis protein RRP36", "aln": "-------------------------------------------------------------MSSPSESSSAS------------------EHEASDD----NETQNAIREDLKGMSFEEIMKLKEELGAKVYKEAVLGSKSSRPQKPKAKTDLKRLNKNRPREMTTRRQVPFLGAEHRVERKKNVEL---RDPRFDEKSG-TYSAETFKKNYQFVSQIRAKEVGQLKKKLD--EVEDEAEKHHIKDTMQRLINKNVEDKKWHTKQKQLKKERSAIQKKHDLGQQPHYLTKKERRAKELVAQFEKLKNTGKLNKHMEKRRKKNAAKDRKRIGIE----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12481-1", "uniprot_id": "RRP36_YEAST", "id": "Q12481-1", "name": "rRNA biogenesis protein RRP36", "aln": "-------------------------------MSYYFKNLKPDLNSDVEEDDGNLLESIMANKSKREIDEQESSDDELKTLSFG----SLKKAETVIDEEDFKDTKPVHKKPITTTYREESFDEDEDSEDQSDEDAGFFEEDSEDETHHGQKVPKKKSKHAPVEQSSKKRVPRVRNIPGLEIPRNKRSNLYQDIRFDKSTGKALDSSIIRKRYQFLDEYREKEIDELQKLLQERKFLSKIDQGEREEMEQRLKSMKSRLQSMKNKDLEREILKEYENDMNKNNNTRYHLKKSEKRKVVQKWKFDHMK-AKQREKVMERKRKKRLGKEFKQFEFHNRR-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . ** : . . : :. . .*: * * ::: ** : : : :* ***. :* ... : : *:*:.: : ** ::: *. . . .: . : :*: . : : . : : . .: ..*.*.::: ::..:: : : :. :.::*::. *: ::: ", "identical_positions": 22, "similar_positions": 80, "identity": "6.53%" }, { "cls_id": "homologset.agr.SGD:S000005814", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q922R8-1", "uniprot_id": "PDIA6_MOUSE", "id": "Q922R8-1", "name": "Protein disulfide-isomerase A6", "aln": "--MARLVLGLVSCTFFLAVSG--LYSSSDDVIELTPSNFNREVIQSDGLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVNADKHQS--LGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRGDSSSKKDVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGKVKLAAVDATVNQVLASRYGIKGFPTIKIFQKGE----SPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKKTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQYELENALGIGGFGYPAMAAINARKMKFALLKG-SFSEQGINEFLRELSFGRGSTAPVGGGSFPTITPREPWDGKDGELPVEDDIDLSDVELDDLEKDEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63081-1", "uniprot_id": "PDIA6_RAT", "id": "Q63081-1", "name": "Protein disulfide-isomerase A6", "aln": "--MARLVLGLVSCTFFLAVSA--LYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAASALKDVVKVGAVNADKHQS--LGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRGDSSSKKDVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGKVKLAAVDATVNQVLASRYGIKGFPTIKIFQKGE----SPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKKTCEEHQLCVVAVLPHILDTGATGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQYELENALGIGGFGYPAMAAINARKMKFALLKG-SFSEQGINEFLRELSFGRGSTAPVGGGSFPNITPREPWDGKDGELPVEDDIDLSDVELDDLEKDEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15084-1", "uniprot_id": "PDIA6_HUMAN", "id": "Q15084-1", "name": "Protein disulfide-isomerase A6", "aln": "--MALLVLGLVSCTFFLAVNG--LYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHS--LGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGE----SPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINARKMKFALLKG-SFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREPWDGRDGELPVEDDIDLSDVELDDLGKDEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V438-1", "uniprot_id": "PDIA6_DROME", "id": "Q9V438-1", "name": "Protein disulfide-isomerase A6 homolog", "aln": "--MRQLASILLLAFVVGSVSA--FYSPSDGVVELTPSNFDREVLKDDAIWVVEFYAPWCGHCQSLVPEYKKLAKALKGVVKVGSVNADADST--LSGQFGVRGFPTIKIFGANKKSPTDYNGQRTAKAIAEAALAEVKKKVQGVLGG-GGGSSSGGSG---SSSGDDVIELTEDNFDKLVLNSDDIWLVEFFAPWCGHCKNLAPEWAKAAKEL----KGKVKLGALDATAHQSKAAEYNVRGYPTIKFFPAGSKRASDAQEYDGGRTASDIVSWASDKHVANVPAPELIEIINESTFETACEGKPLCVVSVLPHILDCDAKCRNKFLDTLRTLGEKFKQKQWGWAWAEGGQQLALEESLEVGGFGYPAMAVVNFKKMKFSVLKG-SFSKDGINEFLRDISYGRGHTAPVRGAKKPAIVSVDPWDGKDGQLPTEEDIDLSDIDLD---KDEL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12404-1", "uniprot_id": "MPD1_YEAST", "id": "Q12404-1", "name": "Protein disulfide-isomerase MPD1", "aln": "MLFLNIIKLLLGLFIMNEVKAQNFYDSDPHISELTPKSFDKAIHNTNYTSLVEFYAPWCGHCKKLSSTFRKAAKRLDGVVQVAAVNCDLNKNKALCAKYDVNGFPTLMVFRPPKIDLSKP---------IDNAKKSFSAHANEVYSG-----------------ARTLAPIVDFSLSRIRSYVKKFVRIDTLGSLLRKSP---------------------KLSVVLFSKQDKISPVYKSIALDWLGKFDFYS-------------ISNKKLKQLTDMNPTYEKTPEIFKYLQKVIPEQRQSDK--------------------------------------------------------------SKLVVFDADKDKFWEYEGNSINKNDISKFLRDTFSITPNEGPFSRRSEYIAYLKT------GKKPIKKNHSSSGNKHDEL-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *: .. *.. :*... : ****..*:: : : : :***********: * . ::* *. *..**:*.:*:.* . . * .::.*.****: :* . * . : * . .: .* : :.: .:.: ... :: .. :. **..: : :: :. * . : * . .. :. * .**::: ::: : . : . :...: * ** :* *:.::.*.:***: .*. *: * :.: . *. . * ", "identical_positions": 59, "similar_positions": 114, "identity": "13.08%" }, { "cls_id": "homologset.agr.SGD:S000005815", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L963-1", "uniprot_id": "A0ABK0L963_RAT", "id": "A0ABK0L963-1", "name": "", "aln": "MGKRRCVPPLEPKLAAGCCGVKKPKLS-----GSGTHSPGNQSTTVPGSS---SGPLQTHQHVDSSSGRENVS---------DLTLGP---------GN--------------SP------ITRMNPASGALSPLPRPN----GTANTTKNLVVTAEMCCYCFDVLYCHLYGFPQPRLPRFTNDPYPLFVTWKTGRDKRLRGCIGTFSAMNLHSGLREYTLTSALKDSRFPPLTREELPKLFCSVSLLTNFEDAS--------DYLDWEVGVHGIRIEFINEK-GIKRTATYLPEVAKEQDWDQIQTIDSLLRKGGFKAPITSEFR----KSIKLTRYRSEKVTISYAEYIASRQH-CFQNGTLHAPPLYNHYS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DCA0-1", "uniprot_id": "AMERL_HUMAN", "id": "Q6DCA0-1", "name": "AMMECR1-like protein", "aln": "MGKRRCVPPLEPKLAAGCCGVKKPKLS-----GSGTHSHGNQSTTVPGSS---SGPLQNHQHVDSSSGRENVS---------DLTLGP---------GN--------------SP------ITRMNPASGALSPLPRPN----GTANTTKNLVVTAEMCCYCFDVLYCHLYGFPQPRLPRFTNDPYPLFVTWKTGRDKRLRGCIGTFSAMNLHSGLREYTLTSALKDSRFPPLTREELPKLFCSVSLLTNFEDAS--------DYLDWEVGVHGIRIEFINEK-GVKRTATYLPEVAKEQDWDQIQTIDSLLRKGGFKAPITSEFR----KTIKLTRYRSEKVTISYAEYIASRQH-CFQNGTLHAPPLYNHYS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JZZ6-1", "uniprot_id": "AMERL_MOUSE", "id": "Q8JZZ6-1", "name": "AMMECR1-like protein", "aln": "MGKRRCVPPLEPKLAAGCCGVKKPKLS-----GSGTHSHGNQSTTVPGSS---SGPLQNHQHVDNSSGRENVS---------DLTLGP---------GN--------------SP------ITRMNTASGALSPLPRPN----GTANSTKNLVVTAEMCCYCFDVLYCHLYGFPQPRLPRFTNDPYPLFVTWKTGRDKRLRGCIGTFSAMNLHSGLREYTLTSALKDSRFPPLTREELPKLFCSVSLLTNFEDAS--------DYLDWEVGVHGIRIEFINEK-GIKRTATYLPEVAKEQDWDQIQTIDSLLRKGGFKAPITSEFR----KSIKLTRYRSEKVTISYAEYIASRQH-CFQNGTLHAPPLYNHYS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JHT5-1", "uniprot_id": "AMMR1_MOUSE", "id": "Q9JHT5-1", "name": "Nuclear protein AMMECR1", "aln": "-------------MAAGCCGVKKQKLSSSPPSGSGGGGGASSSSHCSGESQCRAGELGLGGAGTRLNGLGGLSGGGGSGGGGGCPLSPPQGCGGGGGGGGGGGSGSGGGGISLSPPLSCGVGTLLSTPAAATASSPSSS----SSSPGSRKMVVSAEMCCFCFDVLYCHLYGYQQPRTPRFTNEPYPLFVTWKIGRDKRLRGCIGTFSAMNLHSGLREYTLTSALKDSRFPPMTRDELPRLFCSVSLLTNFEDVC--------DYLDWEVGVHGIRIEFINEK-GSKRTATYLPEVAKEQGWDHIQTIDSLLRKGGYKAPITNEFR----KTIKLTRYRSEKMTLSYAEYLAHRQHHHFQNGIGHPLPPYNHYS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZBY1-1", "uniprot_id": "D3ZBY1_RAT", "id": "D3ZBY1-1", "name": "", "aln": "-------------MAAGCCGVKKQKLSSSPPSGSGGGGGASSSSHCSGESQCRAGELGLGGAGTRLNGLGGLSGGGGSGGGGGCTLSPPQGCGGGGGGG----------GISLSPPLSCGVGTLLSTPAAATASSPSSS----SSSPGSRKMVVSAEMCCFCFDVLYCHLYGYQQPRTPRFTNEPYPLFVTWKIGRDKRLRGCIGTFSAMNLHSGLREYTLTSALKDSRFPPMTRDELPRLFCSVSLLTNFEDVC--------DYLDWEVGVHGIRIEFINEK-GSKRTATYLPEVAKEQGWDHIQTIDSLLRKGGYKAPITNEFR----KTIKLTRYRSEKMTLSYAEYLAHRQHHHFQNGIGHPLPPYNHYS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y4X0-1", "uniprot_id": "AMMR1_HUMAN", "id": "Q9Y4X0-1", "name": "Nuclear protein AMMECR1", "aln": "-------------MAAGCCGVKKQKLSSSPPSGSGGGGGASSSSHCSGESQCRAGELGLGGAGTRLNGLGGLTGGGS---GSGCTLSPPQGCGGG-GGG-----------IALSPPPSCGVGTLLSTPAAATSSSPSSSSAASSSSPGSRKMVVSAEMCCFCFDVLYCHLYGYQQPRTPRFTNEPYPLFVTWKIGRDKRLRGCIGTFSAMNLHSGLREYTLTSALKDSRFPPMTRDELPRLFCSVSLLTNFEDVC--------DYLDWEVGVHGIRIEFINEK-GSKRTATYLPEVAKEQGWDHIQTIDSLLRKGGYKAPITNEFR----KTIKLTRYRSEKMTLSYAEYLAHRQHHHFQNGIGHPLPPYNHYS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VCF0-1", "uniprot_id": "Y5902_DROME", "id": "Q9VCF0-1", "name": "Uncharacterized protein CG5902", "aln": "----------------------------------------MSNSHYNNYQ---------QQQPHSSNG---------------------------------------------DP--------EYQHQQMVHQPQRFSN-------GHGMKTVAVPDMCLFCFEVLDCELNNVDGPSVPVFSNDAYPLFVTWKIGRDKRLRGCIGTFSAMELHHGLREYALTSAFKDSRFAPISRDELPRLTVSVSILQNFEEAQ--------GHLDWQLGVHGIRIEFLTER-GCKRTATYLPQVATEQGWDQLQTIDSLLRKGGYRAAITPETR----KSIKLTRYRSQEIQMHYKEYREYQER-RAQFGKVQC--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12012-1", "uniprot_id": "YO289_YEAST", "id": "Q12012-1", "name": "Uncharacterized protein YOR289W", "aln": "----------------------------------------MALRLFRKSSFFAKISMEGPKGSS------------------------------------------------------------PFAFYAFYQLYSHLN-------PGKSSSLSLEDIRRRLYPDFKIDYN-EKTSLFITWKKKSNKHHTIDTNEENYILRGCIGTFAKMPIAHGIEKYSLIAALEDRRFSPIQKRELVDLKCSCNILGNFKTIFRGGGNPNGDIFDWELGKHGIELYFKHPKTGTTCSATFLPDVMPEQHWNKEDTFANLIEKAGYWGNISEVMDNFETYFIEVIRYEGKKSSITYEEFNKQLKDIEA---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : :: : : . . :.:.. .. . .: ********: * : *:.:*:* :*::* **.*: : ** * * .:* **: . :**::* ***.: * : * . :**:**:* ** *:: :*: .*:.*.*: . *: *:: **..:: : * *: : ", "identical_positions": 50, "similar_positions": 66, "identity": "13.37%" }, { "cls_id": "homologset.agr.SGD:S000005816", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51532-1", "uniprot_id": "SMCA4_HUMAN", "id": "P51532-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", "aln": "MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYN--QMKGMGMRSGGHAGMGPPPSPMDQHSQGYP-SPLGGSEHASSPVPASGPSSGPQMSSGPG-GAPLDGADPQALGQ--QNRGPTPFNQNQLHQLRAQIMAYKMLARGQP-LPDHLQMAVQGKR--PMPG---MQQQMPTLPPPSVSATGPGPGPG-------PGPGPGPGPAPPNYSRPHGMGGPN-----MPPPGPSGVPPGMPGQPP--GGPP----KPWPEGPMANAAAPTSTPQKLIPPQP----TGRPSPAPPAVPP--------AASPVMPPQTQSPGQPAQPAPMVP----LHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEVVVCMRRDTALETALNAKAYKRS--KRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTG--EKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESRHCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDD---ESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLN------------------------------------------DLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQS----------------VFTSVRQKIEKEDDSEGEES-----------------EEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSG-----SGSEED---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3TKT4-1", "uniprot_id": "SMCA4_MOUSE", "id": "Q3TKT4-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", "aln": "MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPMPTQGPGGYPQDNMHQMHKPMESMHEKGMPDDPRYN--QMKGMGMRSGAHTGMAPPPSPMDQHSQGYP-SPLGGSEHASSPVPASGPSSGPQMSSGPG-GAPLDGSDPQALGQ--QNRGPTPFNQNQLHQLRAQIMAYKMLARGQP-LPDHLQMAVQGKR--PMPG---MQQQMPTLPPPSVSATGPGPGPG-------PGPGPGPGPAPPNYSRPHGMGGPN-----MPPPGPSGVPPGMPGQPP--GGPP----KPWPEGPMANAAAPTSTPQKLIPPQP----TGRPSPAPPAVPP--------AASPVMPPQTQSPGQPAQPAPLVP----LHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEVVVCMRRDTALETALNAKAYKRS--KRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFREYHRSVTGKLQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEESGSEEEEEEEEEEQPQPAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTG--EKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDE---------------------------------EEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSEAGSSTPTTSTRSRDKDE---ESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSS-GRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLN------------------------------------------DLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQS----------------VFTSVRQKIEKEDDSEGEES-----------------EEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSG-----SGSEED---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K1P7-1", "uniprot_id": "SMCA4_RAT", "id": "Q8K1P7-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", "aln": "MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPMPTQGPGGYPQDNMHQMHKPMESMHEKGMPDDPRYN--QMKGMGMRSGAHTGMGPPPSPMDQHSQGYP-SPLGGSEHASSPVPASGPSSGPQMSSGPG-GAPLDGSDPQALGQ--QNRGPTPFNQNQLHQLRAQIMAYKMLARGQP-LPDHLQMAVQGKR--PMPG---MQQQMPTLPPPSVSATGPGPGPG-------PGPGPGPGPAPPNYSRPHGMGGPN-----MPPPGPSGVPPGMPGQPP--GGPP----KPWPEGPMANAAAPTSTPQKLIPPQP----TGRPSPAPPAVPP--------AASPVMPPQTQSPGQPAQPAPLVP----LHQKQSRITPIQKPRGLDPVEILQEREYRLQARIVHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEVVVCMRRDTALETALNAKAYKRS--KRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFREYHRSVTGKLQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEESGSEEEEEEEEEEQPQPAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTG--EKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDE---------------------------------EEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSEAGSSTPTTSTRSRDKDE---ESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSS-GRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLN------------------------------------------DLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQS----------------VFTSVRQKIEKEDDSEGEES-----------------EEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSDEEQEEDRSG-----SGSEED---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P25439-1", "uniprot_id": "BRM_DROME", "id": "P25439-1", "name": "Brahma chromatin-remodeling complex ATPase subunit", "aln": "MASPSP--ANSPMP-PPQAPSPMAPPSQSPAPSPHSPYPHQQPGPLQGPPPPGHPGAYGHPMQHGPPGQGPPGHHMPPHHQGMIFSKGPHMGMQMPPTGPNMSPYQTHGMPPNAPTQPCIVSPGGPPGGPPPPERSSQENLHALQRAIDSMEEKGLQEDPRYSQLLAMR-ATSKHQHLNGNQVNLLRTQITAYRLLARNKP-ISMQMQQALQAAQQQPPPGPPIGPPGAPGGPPPGSQHAGQPPVPPQQQQQPPPSAGTPPQCSTPPASNPYGPPVPGQKMQVAPPPPHMQQGQPLPPQPPQVGGPPPIQQQQPPQQQQQQSQPPPPEPHQHQLPNGGKPLSMGPSGGQPLIPSSPMQPQVRGTLPGMPPGSQVPQPGGGPQRQVPPAGMPMPKPNRITTVAKPVGLDPITLLQERENRIAARISLRMQELQRLPATMSEDLRLQAAIELRALRVLNFQRQLRMEFVQCTRRDTTLETALNIKLYKRT--KRQGLREARATEKLEKQQKLEAERKRRQKHLEFLAAVLQHGKDLREFHRNNKAQLARMNKAVMNHHANAEREQKKEQERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAFLLSQTDEYISNLTQMVKQHKDDQMKKKEEEGKRLIQFK----KELLMSGEYIGIDEGSIVADMRVHVVEQCTGKKLTGDDAPMLKHLHRWLNMHPGWDWID-DEEDSCGSNDDHKPKVEEQPTATEDATDKAQATG----------NDEDAKDLITKAKVE-DDEYRT------EEQTYYSIAHTIHEKVVEQASIMVNGTLKEYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTISLVTYLMDRKKVMGPYLIIVPLSTLPNWVLEFEKWAPAVGVVSYKGSPQGRRLLQNQMRATKFNVLLTTYEYVIKDKAVLAKIQWKYMIIDEGHRMKNHHCKLTQVLNTHYIAPYRLLLTGTPLQNKLPELWALLNFLLPSIFKSCSTFEQWFNAPFATTG--EKVELNEEETILIIRRLHKVLRPFLLRRLKKEVEHQLPDKVEYIIKCDMSALQRVLYKHMQSKGVLLTDGSEKGKHGKGGAKALMNTIVQLRKLCNHPFMFQHIEEKYCDHTGGHG-VVSGPDLYRVSGKFELLDRILPKLKATNHRVLLFCQMTQCMTIIEDYLGWRQFGYLRLDGTTKAEDRGELLRKFNAKGSDVFVFLLSTRAGGLGLNLQTADTVVIFDSDWNPHQDLQAQDRAHRIGQRNEVRVLRLMTVNSVEERILAAARYKLNMDEKVIQAGMFDQKSTGSERQQFLQTILHQDDNEE--------------------------------EEENEVPDDEMINMMIARSEEEIEIFKRMDAERKKEDEEIHPGRERLIDESELPDWLTKDDDEVERFHYQYDEDTILGRGSRQRKEVDYTDSLTEKEWLKAIDDG--AEFDEEEEEDDSKRKRRK----------RKNRKEESDD---DSLILKRRRRQNLDKRS------KKQMHKIMSAVIKHNQDG--RTLSEPFMKLPSRQRLPDYYEIIKRPVDIKKILQRIEDCKYADLN------------------------------------------ELEKDFMQLCQNAQIYNEEASLIYLDSIALQK----------------VFVGARQRITAAADAAAVAAGDNTGEAHGNGGSDNSDNDDDDGGDDGSDDEEIATTSAAAVKMKLKLNKSLASAPATPTQSSSNVSSGAATTSKKQTRRKRSQKKYTISDDDDDDMD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22082-1", "uniprot_id": "SNF2_YEAST", "id": "P22082-1", "name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "aln": "MNIPQRQFSNEEVNRCYLRWQHLRNEHGMNAPSVPEFIYLTKVLQFAAKQRQELQMQRQQQGISGSQQNIVPNSSDQAELPNNASSHISASASPHLAPNMQLNGNETFSTSAHQSPIMQTQMPLNSNGGNNMLPQRQSSVGSLNATNFSPTPANNGENAAEKPDNSNHNNLNLNNSELQPQNRSLQEHNIQDSNVMPGSQINSPMPQQAQMQQAQFQAQQAQQAQQAQQAQQAQARLQQGRRLPMTMFTAEQSELLKAQITSLKCLVNRKPIPFEFQAVIQKSINHPPDFKRMLLSLSEFARRRQPTDQNNQSNLNGGNNTQQPGTNSHYNNTNTDN----VSGLTRNAPLDSK---DENFASVSPAGPSSVHNAKNGTLDKNSQTVSGTPITQTESKKEENETISNVAKTAPNSNKTHTEQNNPPKPQKPVPLNVLQDQYKEGIKVVDIDDPDMMVDSFTMPNISHSNIDYQTLLANSDHAKFTIEPGVLPVGIDTHTATDIYQTLIALNLDTTVNDCLDKLLNDECTESTRENALYDYYALQLLPLQKAVRGHVLQFEWHQNSLLTNTHPNFLSKIRNINVQDALLTNQLYKNHELLKLERKKTEAVARLKSMNKSAINQYNRRQDKKNKRLKFGHRLIATHTNLERDEQKRAEKKAKERLQALKANDEEAYIKLLDQTKDTRITHLLRQTNAFLDSLTRAVKDQQKYTKEMIDSHIKEAS-----------------------EEVDDLSMVPKMKDEEYDDDDDN-----SNVDYYNVAHRIKEDIKKQPSILVGGTLKDYQIKGLQWMVSLFNNHLNGILADEMGLGKTIQTISLLTYLYEMKNIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLTTFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFANTGGQDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQMLKYRRLFIG--DQNNKKMVGLRGFNNQIMQLKKICNHPFVFEEVEDQINPTR------ETNDDIWRVAGKFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVILERAYKKLDIDGKVIQAGKFDNKSTSEEQEALLRSLLDAEEERRKKRESG--------------------------VEEEEELKDSEINEILARNDEEMAVLTRMDEDRSKKEEELG-VKSRLLEKSELPDIYSRDIGAELKREESESAAVYNGRGARERKTATYNDNMSEEQWLRQFEVSDDEKNDKQARKQRTKKEDKSEAIDGNGEIKGENIDADNDGPRINNISAEDRADTDLAMNDDDFLSKKRKAGRPRGRPKKVKLEGSENSEPPALESSPVTGDNSPSEDFMDIPKPRTAGKTSVKSARTSTRGRGRGRGRGRGRGRGRGRPPKARNGLDYVRTPAAATSPIDIREKVAKQALDLYHFALNYENEAGRKLSDIFLSKPSKALYPDYYMIIKYPVAFDNINTHIETLAYNSLKETLQDFHLIFSNARIYN--TEGSVVYEDSLELEKVVTKKYCEIMGDNSQLDFTEFDEQYGTRPLVLPPVVTSSVAESFTDEADSS------MTEASV--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *. .. :*. . . .. . . . . .. * .. ** :.. . .: . :: :: . :* .::. .: . * :* : . . . . . . * . . . .* * : . *. : : . . : .: : * . .. * *. : . . : . . :. . . :..: : . : *: * . .::: :: . : :* * .: : * .. .: *: :. :: : . .: : * ... . : :: : *** : : * .*:. . . : : :: : :. : *::.* * :. * ::.*..: :. ::.:: *: . : : * . : . . . :: . : :. : .:. .: . ::. .: * :: : * : *: ** :** : * : :*.:::*.*.**:******:*:***:**:******************:*:*** : *.: **:*:*******.** ** ****:: :*:**** *: ::*: :*:*:***:**:**:: :*:*::* :**:******** :.**: .***** * **:********:**********:**.**:* .:*::***:*** ** :*::*.****:*:******************:** :**:*** ::**.*****:::*::* *: . ::.:: * : : * *:**:*:****::*:.:*:. . *::*.:*************:**.*:**:* ***. * *:**:: : : ****** **:::*. **: ** .*: : *:*************:****:***:*******************:****:*** *.***** ** * **::* ****** **:**:. *:. :*:::*. ::: . **:* .*. :* ::** :**: :: *** :* ::: . : **:::.***. :* : . . ***:*.** . *.*.::*::**: :: . : ::: .:. :.:: : .. . :.* :. : * . .:: : . * : .. . . : . * . ::: * . :.. : . .: *: : * : * :: *.. * : : .* . . :* : : . ::. : *. .. : . . . :: . : :.. . * : . ", "identical_positions": 384, "similar_positions": 442, "identity": "21.54%" }, { "cls_id": "homologset.agr.SGD:S000005817", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CTG6-1", "uniprot_id": "AT132_MOUSE", "id": "Q9CTG6-1", "name": "Polyamine-transporting ATPase 13A2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSADSSLLMGSTPPSYGTLTTGTS--------------------------------------------IDPLSSSASSVRLSGYCGSPWRAIGYHAAVWMLAGIPWLLFRWKPLWGVRLRLKPCSLAHAETLVIEIK-DKEGSSRQLFTVQVQTEAVVQGSLELPPQAQAEDGRSQAAVG-VTPEGTWQDTSELHRQEE-----AKQVLRYYVLQGQRYVWMETQQAFCQVSLLDHGRTCDDVHCSSS-GLSLQDQATRKTIYGPNVISIPVKSYLQLLADEALNPYYGFQAFSIALWLADHYYWYALCIFLISAISICLALYKTRKQSLTLRDMVKLSVR--VQVCRPGGEEEWVDSSELVPGDCLVLPQE-GGVMPCDAALVAGECVVNESSLTGESTPVLKTALPEGP--------KPYCPETHR-RHTLFCGTLILQARAY-VGPRVLAVVTRTGFCTAKGGLVSSILHPRPISFKFYKHSMKFVAALSVLALLGTVYSIIILYRNRVPVREIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRTQGIFCIHPLRINLGGKLRLVCFDKTGTLTEDGLDVMGVVP--------------------LKGQVLLPLVPEPCHLPLGPLLRALATCHALSQLHDTPVGDPMDLKMVESTGWVLEEGP--AAGSAPGSQVLVVMRPPPGGPRQQ-------------EEPPVP---------------VSVLCRFPFSSALQRMDVVVTWPGATQPEAYVKGSPELVASLCSPETVPSDFSQVLQSYTAAGYRVVALAGKPLPIAPSLAAAQQLTRDTVERELSLLGLLVMRNLLKPQTAPVIQTLRKTGIRTVMVTGDNLQTAVTVARACGMVGAQEHLAVIHATHPEQGQ--------------PAALEFLPTESSAVMNGAK--------------------------------------------------------------------------ATGYPTVPEPQSC--HLALSGSTFAVLRKHFP----KLLPKVLVQATVFARMAPEQKTELVCELQRLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPTVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPAL-TLVRARPPGALLSVPVLGSLLLQVALVAGIQLGGYFLVIAQPWFVPLNRTVPAPDN-------------------------LPNYENTVVFSLSGFQYLILAAAVSKGAPFRQPLYTNVPFLVALALLGSVLVGLILVPG-LLQGPLGLRNIVDSSFKLLLLGLVAFNFVGAFMLESVLDQCLPA---CLRWLRPKRASKKQFKRLQQELAEHP-WPTLPVGSVR------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1MAA4-1", "uniprot_id": "F1MAA4_RAT", "id": "F1MAA4-1", "name": "Polyamine-transporting ATPase 13A2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSADSSPLLGSTPPSYGTLMTGTS--------------------------------------------IDPLSSSVSSVRLSGYCGSPWRAIGYHAAVWMLAGIPWLLFRWKPLWGVRLRLRPCSLARAETLVIEIR-DKEGSSRQLFTVQVQTEAVVDGSLELPSQAKAEDGRSLAAVG-VAPESMWQDTTQLHRQKE-----AKQVLRYYILQGQRYVWMETQQAFCQVSLLDHGRACDDIHCSSS-GLSLQDQAVRKTIYGPNVIGIPVKSYLQLLVDEALNPYYGFQAFSIALWLADHYYWYAVCIFLISAISICLSLYKTRKQSMTLRDMVKLSVR--VQVCRPGGEEEWVDSSELVPGDCLVLPQE-GGMMPCDAALVAGECVVNESSLTGESIPVLKTALPEGP--------QPYCPETHR-RHTLFCGTLVLQARAY-LGPRVLAVVTRTGFCTAKGGLVSSILHPRPISFKFYRHSMKFVAALSVLALLGTIYSIIILYRNRVPVKEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRTQGIFCIHPLRINLGGKLRLVCFDKTGTLTEDGLDIMGVVP--------------------LKGQMLLPLVPEPCHLPPGPLLRALVTCHALSQLHDTLVGDPMDLKMVESTGWVLEEGS--AAGSAPETQVLVVMRPPPRGPQQQ-------------EESPEP---------------VSVLRRFPFSSALQRMDVVVTWPGATQPEAYVKGSPELVASLCSPETVPRDFPQVLQSYTAAGYRVVALAGKPLPTAPSLEAAQQLTRDTVEQELSLLGLLVMRNLLKPQTTPVIQTLRKTGIRTVMVTGDNLQTAVTVAKACGMVGTQEHLAIIHATHPEQGQ--------------PAALEFLPTEPSAAMNGAKD----------------------------------------------------------------------PVQATDYPVEPESQSR--HLALSGSTFAVLQKHFP----KLLPKVLVQATVFARMAPEQKTQLVCELQRLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPTVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLAIDLFITTTVAVLMSRTGPAL-TLVRARPPGALLSVPVLGSLLLQVALVAGIQLGGYFLVIAQPWFVPLNRTVPAPDN-------------------------LPNYENTVIFSLSGFQYLILAAAVSKGAPFRQPLYTNVPFLVALALLGSVLVGLILVPG-LLQGPLGLRNIADSSFKLLLLGLVAFNFVGAFMLESVLDQCLPA---CLQWLRPKRASKKQFKQLQRELAERP-WPTLPVGSVR------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQ11-1", "uniprot_id": "AT132_HUMAN", "id": "Q9NQ11-1", "name": "Polyamine-transporting ATPase 13A2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSADSSPLVGSTPTGYGTLTIGTS--------------------------------------------IDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGIPLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIR-DKEDSSWQLFTVQVQTEAIGEGSLEPSPQSQAEDGRSQAAVG-AVPEGAWKDTAQLHKSEEAVSVGQKRVLRYYLFQGQRYIWIETQQAFYQVSLLDHGRSCDDVHRSRH-GLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMR--VCVCRPGGEEEWVDSSELVPGDCLVLPQE-GGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGL--------GPYCAETHR-RHTLFCGTLILQARAY-VGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVP--------------------LKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEP--AADSAFGTQVLAVMRPPLWEPQLQAM-----------EEPPVP---------------VSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ--------------PASLEFLPMESPTAVNGVKD----------------------------------------------------------------------PDQAASYTVEPDPRSR--HLALSGPTFGIIVKHFP----KLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPAL-VLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLAQPWFVPLNRTVAAPDN-------------------------LPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVALALLSSVLVGLVLVPG-LLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPA---CLRRLRPKRASKKRFKQLERELAEQP-WPPLPAGPLR------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XF90-1", "uniprot_id": "AT134_MOUSE", "id": "Q5XF90-1", "name": "Probable cation-transporting ATPase 13A4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDHLEKSQH--------------------------------------------ALLNEGDENEMEIFGYRTQGCRKALCLIGSIFSLGMLPLVFYWRPAWRVWANCVPCSLQEADVVLLKT--TDEFKIYSWKKVIWISLS--------ALSSTSGLTPDHPLIT----DEGYIINRAIRKPDLK--------VRYIKVQKIRYVWNNLEGQFQKIGSLEDWLSSAKIHQKFGLGLTSEEQEIRRLICGPNAIDVEITPIWKLLIKEVLNPFYIFQLFSVCLWFSEDYKEYALAIILMSVISIALTVYDLRQQSVKLHHLVESHNSITVSVYERKAGAQDLESRLLVPGDLLILTGS-RVQMPCDAILIDGSCVVDEGMLTGESIPVTKTPLSQTASSVP---WKMQSEADPR-RHVLFCGTEVIQAKAA-GSGAVRAVVLQTGFNTAKGDLVRSILYPKPMNFKLYRDAIRFLLCLVGTATIGMVYTLCVYVLSGEPPEEVVRKALDVITIAVPPALPAALTTGIIYAQRRLKKKGIFCISPQRINVCGQLNLVCFDKTGTLTRGGLDPWGVVP------------------CDQNGFQAVHSFASGKALPQGPLCAAMASCHSLILLDGTIQGDPLDLKMFEATKWEMTASG--DDLHIKEMLAHTIVVKPTDMVG---------------QVPAEG---------------LAIVHQFPFSSALQRMTVIVQEMGGGRL-AFMKGAPERVASFCQPDTVPTSFISELQIYTTQGFRVIALAYKKLEMD---CPTTALMREKVESDLVFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKSGMVSEGQKVILVEANEATGSS--------------SASISWKLVEEKKPGPFGS--------------------------------------------------------------------QDTYINIREEVPENGRDRS-YHFALSGKSFHVISQYFS----SLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKYMALYSMIQYVGVLLLYWKTNSLSNYQFLFQDLAITTLIGVTMNLNGANP-KLVPFRPAGRLISPPLLLSVVLNILLSLAMHIVGFILVQKQPWYIMDY-HSVCPVRNESASALAASPS---VPEKTRSNSTFASFENTTIWFLGTINCIFVALVFSKGKPFRQPTYTNYIFVLVLILQMGVCLFILFADIPEMHRRLDLLCTPVL-WRVYILIMISSNFVVSLAVEKAIIENRAL-WIAVKRCFGYQS-KSQYRIWQRNLANDSSWPPLNQTSYSDM----QGVSYSNPVFESNEEQL-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M9L4-1", "uniprot_id": "F1M9L4_RAT", "id": "F1M9L4-1", "name": "Cation-transporting ATPase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDHLGKSQH--------------------------------------------ALLNEGDENEMEIFGYRTQGCRKALCLIGSIFSLGMLPLVFYWRPAWRVWANCVPCSLQEADIVLLRT--TDEFKIYSWKKVMWISLS--------ALSSTSGLTPDHPLIA----DEEFIINRAIRKPDLK--------VRYIKVQKIRYVWNNLEGQFQKIGSLEDCLSSAKIHQKFGLGLTSEEQEIRRLICGPNAIDVEIIPIWKLLVKEVLNPFYIFQLFSVCLWFSEDYKEYALAIILMSVISIALTVYDLRQQSVKLHHLVESHNSITVSVYERKAGAQDLESRLLVPGDLLILTGS-RVQMPCDAVLIDGSCVVDEGMLTGESIPVTKTPLSQTASSAP---WKMQSEADPR-RHILFCGTEVIQAKAA-GSGTVRAVVLQTGFNTAKGDLVRSILYPKPMNFKLYRDAIRFLLCLVGTATIGMIYTLCVYVLSGEPPEEVVRKALDVITIAVPPALPAALTTGIIYAQRRLKKKGIFCISPQRINVCGQLNLVCFDKTGTLTRGGLDLWGVVP------------------CDQNGFQAVHSFASGEAVPWGPLCAAMATCHSLILLDGTIQGDPLDLKMFEATQWEMTVSG--DDFHNKEMLAHTMVVKPPDTVG---------------QVPAEG---------------LAILHQFPFSSALQRMTVIVQETGGGRM-AFMKGAPERVASFCQPDTVPTTFISELQVYTTQGFRVIALAYKKLETD---CPTTTLMREKVESDLIFLGLLILENRLKEETRPVLEELISARIRTAMITGDNLQTAITVARKSGMVSEGQKVILVEANEATDSS--------------SASITWKLVEEKKHGLFGS--------------------------------------------------------------------QDTYINIREEVPENGREGN-YHFALSGKSFQVISQHFS----SLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGVSLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKYMALYSMIQYVGVLLLYWKTNSLSNYQFLFQDLAITTLIGVTMNLNGANP-KLVPFRPAGRLISPPLLLSVILNILLSLAMHIVGFILVQKQPWYSMDY-HSVCPVRNESVSALSASPN---VPEKTRSNSTFASFENTTIWFLGTINCIVVALVFSKGKPFRQPTYTNYIFVLVLILQMGVCLFILFADIPELHRRLDLLCTPVL-WRVYILIMVSSNFVVSLAVEKAIIENRAL-WTAVKRCFGYHS-KSQYRVWQRNLATDSSWPPLNQTSYSDM----QGVSYSNPVFESNEEQL-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4VNC1-1", "uniprot_id": "AT134_HUMAN", "id": "Q4VNC1-1", "name": "Probable cation-transporting ATPase 13A4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MG-HFEKGQH--------------------------------------------ALLNEGEENEMEIFGYRTQGCRKSLCLAGSIFSFGILPLVFYWRPAWHVWAHCVPCSLQEADTVLLRT--TDEFQIYSWKKVIWIYLS--------ALNSAFGLTPDHPLMT----DEEYIINRAIRKPDLK--------VRCIKVQKIRYVWNYLEGQFQKIGSLEDWLSSAKIHQKFGSGLTREEQEIRRLICGPNTIDVEVTPIWKLLIKEVLNPFYIFQLFSVCLWFSEDYKEYAFAIIIMSIISISLTVYDLREQSVKLHHLVESHNSITVSVCGRKAGVQELESRVLVPGDLLILTGN-KVLMPCDAVLIEGSCVVDEGMLTGESIPVTKTPLPKMDSSVP---WKTQSEADYK-RHVLFCGTEVIQAKAA-CSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVGTATIGMIYTLCVYVLSGEPPEEVVRKALDVITIAVPPALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDLWGVVS------------------CDRNGFQEVHSFASGQALPWGPLCAAMASCHSLILLDGTIQGDPLDLKMFEATTWEMAFSG--DDFHIKGVPAHAMVVKPCRTAS---------------QVPVEG---------------IAILHQFPFSSALQRMTVIVQEMGGDRL-AFMKGAPERVASFCQPETVPTSFVSELQIYTTQGFRVIALAYKKLEND---HHATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGSS--------------SASISWTLVEEKKHIMYGN--------------------------------------------------------------------QDNYINIRDEVSDKGREGS-YHFALTGKSFHVISQHFS----SLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKYMALYSMIQYVGVLLLYWETNSLSNYQFLFQDLAITTLIGVTMNLNGAYP-KLVPFRPAGRLISPPLLLSVIFNILLSLAMHIAGFILVQRQPWYSVEI-HSACTVQNESISELTMSPT---APEKMESNSTFTSFENTTVWFLGTINCITVALVFSKGKPFRQPTYTNYIFVLVLIIQLGVCLFILFADIPELYRRLDLLCTPVL-WRASIVIMLSLNFIVSLVAEEAVIENRAL-WMMIKRCFGYQS-KSQYRIWQRDLANDPSWPPLNQTSHSDMPECGRGVSYSNPVFESNEEQL-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3TYU2-1", "uniprot_id": "AT135_MOUSE", "id": "Q3TYU2-1", "name": "Probable cation-transporting ATPase 13A5", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKSKKDGHQ--------------------------------------------AVLNEGEENELEVFGYHTQNLRRALCLVTAILTLGAVQLMFYWRPEWWVWTSCIPCPLQEADTILLRT--TDEFRRYMRKKVFCLHLS--------TLKFPISKNPEEPLVA----DHHSVINQAVMKPELK--------LRCIQVQKIRYVWDFLKKRFQKVGLLEDSNSCFDIHHTFGLGLTNEEQEVRRLVCGPNSIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDLRQQSVKLHKLVEEHNKVQVTITVRDKGLQELESRLLVPGDILILPG--KISLPCDAILIDGSCVVNEGMLTGESIPVTKTPLPQTENTMP---WKSHSLEDYR-KHVLFCGTEVIQVKPS-AQGLVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYNDAFKFMVFLACVGVVGFFYALGVYMYHEVPPRETATMALILLSATVPPVLPAALTIGNVYAQKRLKKEKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTVP------------------TAGNCFQAVHSFASGEAVPWGPLCAAMTSCHSLILLDGTIQGDPLDLKMFEGTGWNMEDSQ--VASCKFGMADSSTVIKPGPKAS---------------QSPVDS---------------ITILRQFPFSSGLQRMSVIAQLAGDLHLHVYMKGAPEMVARFCRSETVPKNFSQELRNYTVQGFRVIALAHKTLKMER-LSDMDHLAREKVESELAFLGLLIMENRLKKETRPVLKELSEARIRTVMVTGDNLQTAITVAKNSEMIPVGSQVVIVEANEPGDLV--------------PASVTWQLVGTQEPGSGK---------------------------------------------------------------------KDTYIDIGNSSVPAGKG---YHFAMSGKSYQVLFHHFY----SMLPQILVNGTIFARMSPGQKSSLVEEFQKLNYYVGMCGDGANDCGALKMAHAGISLSEQEASVASPFTSKTANIECVPHLIREGRAALVSSFGVFKYLTMYGIIQFIGTSLLYWQLQLFGNYQYLLQDVAITLMVSLTMSINHAYP-KLAPYRPAGQLLSPQLLLSVFMNSCFTCIVQVCTFLTVKQQPWYCEVYKYSECFLVNQSNLSANVSLDRNWTGNATLVPASVLSFEGTTLWPIVTFNCISAAFIFSKGKPFRKPIYANYLFSLLLASAAGLTIFILFCDFQDLYRKMEFIPTPTS-WRVSILIAAFVQFCVAFFVEDAVLQNREL-WLFIKKEFGFYS-KSQYRILQRKLAEDSTWPPVNRTDYAVN---GKNGFYVNRAYESPEEVPKGKLKLEEQASEQHFWTRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1MA70-1", "uniprot_id": "F1MA70_RAT", "id": "F1MA70-1", "name": "Cation-transporting ATPase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKSKTDGHQ--------------------------------------------AVLNEGEENELEVFGYQTQNLRRALCLVTAILTLGAVQLMFYWRPEWWVWTSCIPCPLQEADIVLLRT--TDEFRRYMRKKVFCLHLS--------TLKIPISKNPGEPLVA----DHHSVINQAVMKPELK--------LRCIQVQKIRYVWDFLKKRFQKVGLLEDSNSCFDIHHTFGLGLTSEEQEVRRLVCGPNAIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDLRQQSVKLHKLVEDHNKVQVTITVRDKGLQELESRLLVPGDILILPG--KISLPCDAVLIDGSCVVNEGMLTGESIPVTKTPLPQTENTMP---WKSHSLEDYR-KHVLFCGTEVIQVKPS-GQGPVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYNDAFKFMVFLACIGVVGFFYALGVYLYHEVPPRETVTMALILLTATVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTVP------------------TAGNCFQAVHSFASGEAVPWGPLCAAMASCHSLILLDGTIQGDPLDLKMFEGTGWNMEDGQ--VASCKYSTADSGTVIKPGPNAS---------------QSPVDS---------------ITILRQFPFSSGLQRMSVIAQLAGDLRLHVYMKGAPEMVARFCSSETVPKNFPQELRNYTVQGFRVIALAHKTLKMEK-VSDVERLAREKVESELAFLGLLIMENRLKNETRPVLQELSEARIRTVMVTGDNLQTAITVAKNSEMIPVGSQVIIVEANEPGDLV--------------PASVTWQLVGTQEPGSEKKVSQGSQQCFRS------------------------------------------------PCRNHAFRFQDTYIDIGNSSVPCGKG---YHFAMSGKSYQVLFHHFY----SMLPQILVNGTVFARMSPGQKSSLVEEFQKLNYYVGMCGDGANDCGALKMAHAGISLSEQEASVASPFTSKVANIECVPHLIREGRAALVSSFGVFKYLTMYGIIQFIGTSLLYWQLQLFGNYQYLLQDVAITLMVSLTMSINHAYP-KLAPYRPAGQLLSPQLLLSVFMNSCFTCIVLVCTFLSVKQQPWYCEVYKYSECFLVNQSNFSTNMGLERNWTGNATLVPASVLSFEGTTLWPIVTFNCISAAFIFSKGKPFRKPIYTNYLFSLLLTSAVGLTVFILFSDFQDIYRRMEFIPTTTS-WRISILVAAFVQFCVAFFVEDAILQNREL-WLFIKKEFGFYS-KSQYRILQRKLAEDSTWPPTNRTDYAVN---GKNGLYINRAYESPEQVPKGKLKLGGQASEQHFWTRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4VNC0-1", "uniprot_id": "AT135_HUMAN", "id": "Q4VNC0-1", "name": "Probable cation-transporting ATPase 13A5", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEENSKKDHR--------------------------------------------ALLNQGEEDELEVFGYRDHNVRKAFCLVASVLTCGGLLLVFYWRPQWRVWANCIPCPLQEADTVLLRT--TDEFQRYMRKKVFCLYLS--------TLKFPVSKKWEESLVA----DRHSVINQALIKPELK--------LRCMEVQKIRYVWNDLEKRFQKVGLLEDSNSCSDIHQTFGLGLTSEEQEVRRLVCGPNAIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDLRQQSVKLHNLVEDHNKVQVTIIVKDKGLEELESRLLVPGDILILPG--KFSLPCDAVLIDGSCVVNEGMLTGESIPVTKTPLPQMENTMP---WKCHSLEDYR-KHVLFCGTEVIQVKPS-GQGPVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYSDAFKFIVFLACLGVMGFFYALGVYMYHGVPPKDTVTMALILLTVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTVP------------------TADNCFQEAHSFASGQAVPWSPLCAAMASCHSLILLNGTIQGDPLDLKMFEGTAWKMEDCI--VDSCKFGTSVS-NIIKPGPKAS---------------KSPVEA---------------IITLCQFPFSSSLQRMSVIAQLAGENHFHVYMKGAPEMVARFCRSETVPKNFPQELRSYTVQGFRVIALAHKTLKMGN-LSEVEHLAREKVESELTFLGLLIMENRLKKETKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMIPPGSQVIIVEADEPEEFV--------------PASVTWQLVENQETGPGK---------------------------------------------------------------------KEIYMHTGNSSTPRGEGGSCYHFAMSGKSYQVIFQHFN----SLLPKILVNGTVFARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCGALKAAHAGISLSEQEASVASPFTSKTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGIIQFISALLLYWQLQLFGNYQYLMQDVAITLMVCLTMSSTHAYP-KLAPYRPAGQLLSPPLLLSIFLNSCFSCIVQISAFLYVKQQPWYCEVYQYSECFLANQSNFSTNVSLERNWTGNATLIPGSILSFETTTLWPITTINYITVAFIFSKGKPFRKPIYTNYIFSFLLLAALGLTIFILFSDFQVIYRGMELIPTITS-WRVLILVVALTQFCVAFFVEDSILQNHEL-WLLIKREFGFYS-KSQYRTWQKKLAEDSTWPPINRTDYSGD---GKNGFYINGGYESHEQIPKRKLKLGGQPTEQHFWARL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XF89-1", "uniprot_id": "AT133_MOUSE", "id": "Q5XF89-1", "name": "Polyamine-transporting ATPase 13A3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDKEER--------------------------------------------KTINKGQEDEMEIHGYNLCRWKLAMVFVGVICTGGFLLLLLYWLPEWRVKATCVRAAVKDCEVVLLRT--TDEFRVWFCAKIHFLPVENQPNLNAKCLVNEVSNGHAVHLTE----ENRCEMNKYSQSQSQQ--------MRYFTHHSIRYFWNDAIHNFDFLKGLDEGVSCASLYEKHSAGLTQGMHAYRKLIYGVNEIAVKVPSVFKLLIKEVLNPFYIFQLFSVILWSVDEYYYYALAIVIMSVVSIISSLYSIRKQYVMLHDMVATHSTVRVSVCRENEEIEEIFSTDLVPGDVMIIPLN-GTVMPCDAVLINGTCIVNESMLTGESVPVTKTNLPNPSVDVKGMGEEQYSPETHK-RHTLFCGTTVIQTRFY-TGELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLLCLVVVAGIGFIYTIINSILNEKEVQEIIIKSLDIITITVPPALPAAMTAGIVYAQRRLKKVGIFCISPQRINICGQLNLVCFDKTGTLTEDGLDLWGIQR------------------VENTRFLLPEDNVCSEMLVKSQFVACMATCHSLTKIEGVLSGDPLDLKMFEAIGWILEEAT--EEETALHNRIMPTVVRPSKQLL---------------PEPTTAGNQEMELFELPAIYEIGIVRQFPFSSALQRMSVVARTLGEKRMDAYMKGAPEVVASLCKPETVPVDFEKVLEDYTKQGFRVIALAHRKLESKLTWHKVQHISRDAIENNMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDNMLTAVSVARDCGMILPQDKVIIAEALPPKDGK--------------VAKINWHYTDSLSQCSESS----------------------------------------------------------------AIDSEAIPIKLAHDSLEDLEVTR-YHFAMNGKSFSVILEHFQ----DLVPKLMLHGTVFARMAPDQKTQLVEALQNVDYFVGMCGDGANDCGALKRAHGGISLSELEASVASPFTSKTPSISCVPNLIREGRAALMTSFCVFKFMALYSIIQYFSVTLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAWK-ELVAQRPPSGLISGALLFSVLSQIVISVGFQSLGFFWVKQ---YKVCDPNSDVCNTTRSACWNSSHLYN----GTELDSCKIQNYENTTVFFISSFQYLTVAVAFSKGKPFRQPCYKNYFFVISVIILYVFILFIMLHPVASVDQVLEIMCVPYQ-WRIYMLIIVLINAFVSITVEESVDRWGKC-CLSWALSCRKKTPKAKYMYLAQELRFDPEWPPKPQTTTEAK-----AVVKENGSCQIITIA--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AAY5-1", "uniprot_id": "A0A8I6AAY5_RAT", "id": "A0A8I6AAY5-1", "name": "Polyamine-transporting ATPase 13A3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDKEER--------------------------------------------TIINKGQEDEMEIHGYNLCRWKLAMVCVGVICTGGFLLLLLYWMPEWRVKATCVRAAVKDCEVVLLRT--TDEFRIWFCAKIHFLSLENQPNLNAKSLVNKVSNGHAVRLTE----ENRCEMNKYSQSQSQQ--------MRYFTHHSIRYFWNDAIHNFDFLKGLDEGVSCASMYEKHSAGLTKGMHAYRKLLYGVNEIAVKVPSVFKLLIKEVLNPFYIFQLFSVILWSIDEYYYYALAIVVMSIVSIISSLYSIRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPGDVMIIPLN-GTVMPCDAVLINGTCIVNESMLTGESVPVTKTNLPNPSVDVKGMGEEQYSPETHK-RHTLFCGTTVIQTRFY-TGELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLLCLVVVAGIGFIYTIVNSILNEKEVQEIIIKSLDIITITVPPALPAAMTAGIVYAQRRLKKVGIFCISPQRINICGQLNLVCFDKTGTLTEDGLDLWGIQR------------------VENTRFLLPEDNVCNEMLVKSQFVACMATCHSLTKIEGVLSGDPLDLKMFEAIGWVLEEAT--EEETALHNRIMPTVVRPSKQLL---------------PESTTAGDQEMELFELPAIYEIGIVRQFPFSSALQRMSVVARTLGDKRMDAYMKGAPEVIASLCKPETVPVDFEKVLEDYTKQGFRVIALAHRKLESKLTWHKVQHVSRDAIENNMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDNMLTAVSVARDCGMILPQDKVIIAEALPPKDGK--------------VAKINWHYTDSLTQCSESS----------------------------------------------------------------AIDSEAIPIKLAHDSLEDLQVTR-YHFAMNGKSFSVILEHFQ----DLVPKLMLHGTVFARMAPDQKTQLVEALQNVDYFVGMCGDGANDCGALKRAHGGISLSEFEASVASPFTSKTPSISCVPNLIREGRAALMTSFCVFKFMALYSIIQYFSVTLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAWK-ELVAQRPPSGLISGALLFSVLSQIVISVGFQSLGFFWVKQ---YKECDPYSEVCNTTRSACWNSSHLYN----GTELDSCKIQNYENTTVFFISSFQYLTVAVAFSKGKPFRQPCYKNYFFVISVIILYVFILFIMLHPVASVDQLLEIMCVPYQ-WRIYMLIIVLTNAFVSITVEESVDRWGKC-CLSWALSCRKKTPKAKYMYLAQELQFDPEWPPKPQTTTEAK-----AIVKENGSCQIITIA--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H7F0-1", "uniprot_id": "AT133_HUMAN", "id": "Q9H7F0-1", "name": "Polyamine-transporting ATPase 13A3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDREER--------------------------------------------KTINQGQEDEMEIYGYNLSRWKLAIVSLGVICSGGFLLLLLYWMPEWRVKATCVRAAIKDCEVVLLRT--TDEFKMWFCAKIRVLSLETYPVSSPKSMSNKLSNGHAVCLIENPTEENRHRISKYSQTESQQ--------IRYFTHHSVKYFWNDTIHNFDFLKGLDEGVSCTSIYEKHSAGLTKGMHAYRKLLYGVNEIAVKVPSVFKLLIKEVLNPFYIFQLFSVILWSTDEYYYYALAIVVMSIVSIVSSLYSIRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPGDVMVIPLN-GTIMPCDAVLINGTCIVNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNPETHK-RHTLFCGTTVIQTRFY-TGELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLLCLVAVAGIGFIYTIINSILNEVQVGVIIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFCISPQRINICGQLNLVCFDKTGTLTEDGLDLWGIQR------------------VENARFLSPEENVCNEMLVKSQFVACMATCHSLTKIEGVLSGDPLDLKMFEAIGWILEEAT--EEETALHNRIMPTVVRPPKQLL---------------PESTPAGNQEMELFELPATYEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAIAGLCKPETVPVDFQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQNISRDAIENNMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALPPKDGK--------------VAKINWHYADSLTQCSHPS----------------------------------------------------------------AIDPEAIPVKLVHDSLEDLQMTR-YHFAMNGKSFSVILEHFQ----DLVPKLMLHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRAHGGISLSELEASVASPFTSKTPSISCVPNLIREGRAALITSFCVFKFMALYSIIQYFSVTLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAWK-ELVAQRPPSGLISGALLFSVLSQIIICIGFQSLGFFWVKQQPWYEVWHPKSDACNTTGSGFWNSSHVDN----ETELDEHNIQNYENTTVFFISSFQYLIVAIAFSKGKPFRQPCYKNYFFVFSVIFLYIFILFIMLYPVASVDQVLQIVCVPYQ-WRVTMLIIVLVNAFVSITVEESVDRWGKC-CLPWALGCRKKTPKAKYMYLAQELLVDPEWPPKPQTTTEAK-----ALVKENGSCQIITIT--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8DZ26-1", "uniprot_id": "A8DZ26_DROME", "id": "A8DZ26-1", "name": "Cation-transporting ATPase", "aln": "------------------------------------------------------------------------------------------------------------------MFASQSKACDSPSETVHLQSLPNHIEDLKFRNSDVETDDDLHFPGIAAKNKILKLSWWHSPVDMHYVATESVQPKKSDKVPSNKIKKVENNNTLVNGCSKTSARSVPLLKYNRPDQDGDSEENITSVLEPNVDEIYSKDSERLVDDSKP----------------------------------CIGLLNPDQEDQMKVCGYRRSLMRTGFCWACIFLTGGLLRLVLHWWRHLYLYATCSQCSLEEAEQVLVTEDYQGKHKMYHVKQIQVLTSSN-----LKTLLEKEQQSIERTHIECDHVENVLQLSVHFTSAQFKK----CSSIRIFRCKQLVYAWNNNTNRFQRINGLDLNIPCSYYHQQR--GLPVHEQISRRIVFGDNEITVPLRDFKTLLFLEVLNPFYVFQLFSVILWFTYDYYYYACVILLMSVFGITVSVLQTKKNQDVLQKTVYNTG--NAWVVDHKGLSKELPTRAIVPGDIIEIPSS-GCTLHCDAILISGNCILDESMLTGESVPVTKTPLPSKR-------DMIFDKTEHA-RHTLFCGTKVIQTRYI-GSKKVLAFVINTGNITAKGELIRSILYPPPVDYKFEQDSYKFIQFLAIIACVGFIYTLVTKILRGTDPVKIAVESLDLITIVVPPALPAAMTVGRFYAQKRLKTSEIFCISPRSINVAGSINCCCFDKTGTLTEDGLDMWGVVPK-----------------SSTNQFQIP--LKSVDRLPFDHFLFGMVTCHSITILNGRMMGDPLDLKMFESTGWELEDSNNIPDTEKYGILYPTILRQPRGGLSGMAETESGSKNEIKRQSSVDDLLATVGISPSQKNFDHGIVREFPFTSALQRMSVVTRCLSDQVFNVYCKGSPEMLKKLCKPQSLPDNYSQQLSEFAKKGYRIIAIAFKALSHKMNYTKVQRLSREEVENNMEFLGFVILENRLKPDTTKVINALNAAKIRTIMITGDNILTAISVARDCGIVSPSQSVITVHADPIGDSANIQTNTGTECNFDNSSDKHYKLHYTLDLGSKTSRAYLFKSCFNSNLFDPETPEFTAQVGKTIFHMESTNSLVNESTSSYAESGLPTSDSLASVKTIDTWTHNDAELGIKHTPDESWRRQE-CIFAMDGKTWQIVKDYFP----EEMEILLTRGSIYARMSPDQKQALVIELQNLDYCVAMCGDGANDCGALKVAHAGISLSETEASIASPFTSRNPTISAVLKVIKEGRAALVTSFGIFKYMAAYSLVQFISVMILYSIDSNLTDKQYLYVDLGLISIFAFFFGKTESFDGMLVEQVPLSSLISSTPLASLLLHLTVVTAFQVTCWVHLHQQPWFKAFEPADEDHLG---------------------------CFENYTMFCISSFQYIILAFVFSKGAPYRKPLWSNWPLCLAFIVNLCIIVYLVLYPSDWVASFFQLIVPPTMRFRYVMLAYGAASFICHIFVESFLVEYLVFKKYQVKREKNWVTSKQKYMRLEHDISNIKNWPPITEVYEPNN---LIDCETEQPTYVSLHAEQNHDTQLGKFPGFC------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12697-1", "uniprot_id": "YPK9_YEAST", "id": "Q12697-1", "name": "Vacuolar cation-transporting ATPase YPK9", "aln": "MDIPSSNQIQHGQRSERNRRMPRASFSSTATTSTAATLTSAMVLDQNNSEPYAGATFEAVPSSIVSFHHPHSFQSSNLPSPHSSGNLEQRGRRLTESEPLVLSSAEQSRSSSRNPSHFRFFTQEQISNAEGASTLENTDYDMAWDATPAYEQDRIYGTGLSSRRSSIRSFSRASSLSNAKSYGSFSKRGRSGSRAPQRLGENSDTGFVYHSATHSSSSLSRYTTRERIPIELESQTDEILEDESSTHSLESSDSRRSASENNRGSFSGHDDVHNQHSEYLKPDYHEKFYPQYAPNLHYQRFYIAEEDLVIGIAAYQTSKFWYIIYNLCCFLTFGLVYLLTRWLPHLKVKLYGVKVPLAKAEWVVIEN----EFGEFVIQPIDRQWYNR-----PLSTVLPFENYPNPSYEP----NDINLSHHHANEINPN-----VPILITFEYRYIKFIYSPLDDLFKTNNNWIDPDWVDLSTVSN--GLTKGVQEDRELAFGKNQINLRMKTTSEILFNEVLHPFYVFQVFSIILWGIDEYYYYAACIFLISVLSIFDSLNEQKKVSRNLAEMSHFHCD---VRVLRDKFWTTISSSELVPGDIYEVSDPNITILPCDSILLSSDCIVNESMLTGESVPVSKFPATEETMYQLCDDFQSTQISSFVSKSFLYNGTNIIRARIAPGQTAALAMVVRTGFSTTKGSLVRSMVFPKPTGFKFYRDSFKYIGFMSLIAIFGFCVSCVQFIKLGLDKKTMILRALDIITIVVPPALPATLTIGTNFALSRLKEKGIFCISPTRLNISGKIDVMCFDKTGTLTEDGLDVLGVQISEPNGVRGQKFGELLSDIRQVFPKFSLNDCSSPLDFKSRNFFMSLLTCHSLRSVDGNLLGDPLDFKMFQFTGWSFEEDFQKRAFHSLYEGRHEDDVFPENSEIIP------------AVVHPDSNNRENTFTDNDPHNFLGVVRSFEFLSELRRMSVIVKTNNDDVYWSFTKGAPEVISEICNKSTLPADFEEVLRCYTHNGYRVIACAGKTLPKRT-WLYSQKVSREEVESNLEFLGFIIFQNKLKKETSETLKSLQDANIRTIMCTGDNILTAISVGREAGLIQCSRVYVPSINDTPLHGEP---------------VIVWRDVNEPDKILDTKT--------------------------------------------------------------------LKPVKLGNNSVESLRECN-YTLAVSGDVFRLLFRDENEIPEEYLNEILLNSSIYARMSPDEKHELMIQLQKLDYTVGFCGDGANDCGALKAADVGISLSEAEASVAAPFTSKIFNISCVLDVIREGRAALVTSFACFQYMSLYSAIQFITITILYSRGSNLGDFQFLYIDLLLIVPIAICMSWSKSYE-KIDKKRPSANLVSPKILVPLLISVFLVFLFQFIPWIIVQKMSWYIKPIVGGDDAVQ---------------------------SSDNTVLFFVSNFQYILTAIVLSVGPPYREPMSKNFEFIVDITVSIGASLLLMTLDTESYLGKMLQLTPISNSFTMFIIVWVILNYYAQLYIPPSIKGWLKK----------KKSSKKYKLLIQEEMKLKEV----------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : .* * *: * : : .: ::: : : : . : : : : * **. : *. * * * : : :* :.*:*:* ** *:: ** * *: *.::: ..* :: . :: * . : : :**** :. : **: *: . *:::*. ***** ** * .. : *: ** :::.: . *.* .** *:** *: *::.* * .::: .: :: : . .* : :* ::: .***.***::* :* **: **** * :*: *.: *********..*** * . : : :**:: :.. ***:*:**.: * : * : * * * *:** *:. . : **:** : :* .::* : . * :: *:*::* * : * : *: :* :: ::*::::.* ** :* .:: * : **: * ***.: **::*.: . :: : :*: * : :: . : :: ..:::***:* :* *: :*.::* *.:************ *. *:***: ***:.:**** .*..* :*:***.:* :** *:::: *. *:. :** : : *:* *: : . . :. . . : * . *:* * .:. . . :. : : .:: : :: : * .* * *:*.* * : . . : :: : : :: . : : : * ..: ", "identical_positions": 198, "similar_positions": 260, "identity": "11.77%" }, { "cls_id": "homologset.agr.SGD:S000005818", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9N8-1", "uniprot_id": "D4A9N8_RAT", "id": "D4A9N8-1", "name": "", "aln": "-----------------------------MAAGGWRWARKALA-----------------------------AGRPLFQGRALLVTNTLGCGVLMATGDGARQAWEVR---------------------------------------------------------------ARPEQRFSARRSASMFAVG-CSMGPFLHFWYLWLDRLLPASGLRSLPSVMKKVLVDQTVASPILGVWYFLGLG-SLEGQTLEESCQELRAKFWDFYKADWCVWPAAQLVNFLFIPSHFRVTYINGLTLGWDTYLSYLKYWAPEPLQTPGCAD----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VIK2-1", "uniprot_id": "M17L2_MOUSE", "id": "Q8VIK2-1", "name": "Mpv17-like protein 2", "aln": "-----------------------------MALGGWRWARKALA-----------------------------AGRPLFQGRALLLTNTLGCGVLMAAGDGARQVWEVR---------------------------------------------------------------ARPGQRFSARRSASMFAVG-CSMGPFLHFWYLWLDRLLPASGLRSLPSVMKKVLVDQTVASPILGVWYFLGLG-SLEGQTLEESCQELRAKFWDFYKADWCVWPAAQLVNFLFIPSHFRVTYINGLTLGWDTYLSYLKYWVPEPLQTPGCAD----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q567V2-1", "uniprot_id": "M17L2_HUMAN", "id": "Q567V2-1", "name": "Mpv17-like protein 2", "aln": "-----------------------------MARGGWRRLRRLLS-----------------------------AGQLLFQGRALLVTNTLGCGALMAAGDGVRQSWEIR---------------------------------------------------------------ARPGQVFDPRRSASMFAVG-CSMGPFLHYWYLSLDRLFPASGLRGFPNVLKKVLVDQLVASPLLGVWYFLGLG-CLEGQTVGESCQELREKFWEFYKADWCVWPAAQFVNFLFVPPQFRVTYINGLTLGWDTYLSYLKYRSPVPLTPPGCVALDTRAD----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DGV7-1", "uniprot_id": "M17L2_DANRE", "id": "Q6DGV7-1", "name": "Mpv17-like protein 2", "aln": "----------------------------MISRQGKEFLVRIAG-----------------------------YWKPLFRGRFLIVTNTVSCGGMLAAGDLIQQTREIR---------------------------------------------------------------RTPGRTRDWSRTGCMFAVG-CSMGPFMHYWYQWLDKYFIGNGIN---NVCKKVLVDQLVASPTLGAWYFLGMG-MMEGHTFIEAQQEFRDKFWEFYKADWCVWPAAQMINFYFLPPKFRVLYVNIVTLGWDTYLSYLKHRDTVEVTKEADGTA---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYD6-1", "uniprot_id": "Q9VYD6_DROME", "id": "Q9VYD6-1", "name": "Mpv17-like protein 2", "aln": "-------MQSLRGCPARGLILSRAIRGQRSLRMSWPRNSSATGGAG-GAAPGGGSSTTTSTIGFGALQKLREWHASAFSSRFLLFTNVGISLTLSCVGDVLEQHLEIY---------------------------------------------------------------CGEIERFESTRTAHMAISG-VTVGVICHYWYKMLDKRMPGRTMR---VVAKKIVLDQLICSPIYISAFFVTLG-LLEQKTKHEVWEEIKEKAWKLYAAEWTVWPVAQFVNFYWIPTHYRIFYDNIISLGYDVLTSKVKHKQSHSHLKKIP------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTQ1-1", "uniprot_id": "Q9VTQ1_DROME", "id": "Q9VTQ1-1", "name": "Mpv17-like protein 2", "aln": "----------------------------MALRVLWRRMTNAMD----------------------------RFHQIAFSPKYLLFTNIGISVGLSMVGDTMEQSYERL---------------------------------------------------------------IGELPDWNRTRTIRMGISG-LTVGLVCHYWYQHLDYLFPKRTYK---VVVVKILLDQFICSPFYIAVFFLTMA-ILEDNTWEELEQEIREKALVLYAAEWTVWPLAQFINFLLIKPQYRVFYDNTISLGYDIYTSQVKYRKKPEPKDNS-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZM6-1", "uniprot_id": "Q9VZM6_DROME", "id": "Q9VZM6-1", "name": "Mpv17-like protein 2", "aln": "------MFGTRCLRQCYSLRIHGSHNSRRDFAALCRMRSHGVGYQKYGLRFTHGKGETEGGALSFILLRWTKIAWSNMFGKYLLVTNVVGSGLLMVVGDVIAQEYEYRRG-------------------------------------------------------------LRHQDRFDTDRMYRMFVAG-ALQGPLHHYVYNWMDRVMPARTLKN---IFKKILIDQLVMSPACIVIFFYSLC-YLERQTLDATNQELISKFPYVYMLDWMTWPAAQYLNFRYLDTKYRVTFVNVCTAVYNVLMSYMKHDFGVHLPLEEKLVASSEQNLLPQSSTTSPDAQKAV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IRC8-1", "uniprot_id": "Q8IRC8_DROME", "id": "Q8IRC8-1", "name": "Mpv17-like protein 2", "aln": "-----MMFS--WTRLANPLKMS------------CQLVTH----------FSTAPPPNAK-------------FWTKLFGKYLLLTNTIGSGLLLAIGDAIAQQYER----------------------------------------------------------------FGEKKAFDYSRSGCMMITG-SVIGPIQHGFYLLLDGVLPGTSGWG---VLHKILVDQLIMSPIYIFLFFYVSS-LLGGKSFVECNSELSEKFLYTWMLDCCFWPGLQYLNFRFLNSLYRVVFVNVANCVYVVLLSHIKYGVSNHDP----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99MS3-1", "uniprot_id": "MP17L_MOUSE", "id": "Q99MS3-1", "name": "Mpv17-like protein", "aln": "------------------------------MASWWRAFPQAAR-------------------------------------RYPWPTNVLLYAGLFSAGDALQQRLRGGP--------------------------------------------------------------------ADWRQTRRVATLAVTFHGNFNYVWLRLLERALPGRAPRT---VLAKVLCDQTVGGPIALSAFYVGMS-VLQGK--DDIFLDLKQKFWNTYKSGLMYWPFVQLTNFSLVPVHWRTAYTGLCAFLWATFLC-FSQQSGDGTLQSIFIFLRRK--EASDKSPEK-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GL80-1", "uniprot_id": "A0A8I6GL80_RAT", "id": "A0A8I6GL80-1", "name": "", "aln": "------------------------------MANWWRAFPRAAR-------------------------------------RYPWPTNVLLYAGLFSAGDALQQRLRGGP--------------------------------------------------------------------ADWRQTRRVATLALTFHGNFNYMWLRLLERALPGRAPRT---VLAKVLCDQTVGGPVALSAFYVGMS-ILQGK--DDIFLDLRQKFWNTYK----------LTNFSLVPVNWRTAYTGLCGFLWATFLC-FSQQSGDGTVESIFILLRRK--EAGDRSPEK-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2QL34-1", "uniprot_id": "MP17L_HUMAN", "id": "Q2QL34-1", "name": "Mpv17-like protein", "aln": "------------------------------MAGWWPALSRAAR-------------------------------------RHPWPTNVLLYGSLVSAGDALQQRLQGRE--------------------------------------------------------------------ANWRQTRRVATLVVTFHANFNYVWLRLLERALPGRAPHA---LLAKLLCDQVVGAPIAVSAFYVGMS-ILQGK--DDIFLDLKQKFWNTYLSGLMYWPFVQLTNFSLVPVQWRTAYAGVCGFLWATFIC-FSQQSGDGTFKSAFTILYTKGTSATEGYPKK-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P841-1", "uniprot_id": "A0A8M1P841_DANRE", "id": "A0A8M1P841-1", "name": "", "aln": "------------------------------MNRIWTLF----K-------------------------------------SHPYIPNVVGYTTLFATADLIQQGVMGKAQDKETEQEVQD---------TLKTSIERFTVSKEGKTDDLTLYNAKTNDAGNQTLSEMQHVPQFHRSFIDWSQTARVALVGFCFHANFNYYWLRGLERMFPGGGTKR---VSLKVILDQLIAAPMTISAFYIGLS-TLEGA--EDPFEDWKNKFWTSYKTGVVYWSTMQAVNFSLIPPAARTVFVGGVALGWTIFLCHFKQQKSD--VRS--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W588-1", "uniprot_id": "Q9W588_DROME", "id": "Q9W588-1", "name": "Mpv17-like protein", "aln": "----------------------MVPAAVKLLQASLGQWRRGSK-------------------------------------LHPMAKGALTYAVMWPAGSLIQQAMEGRK-----------------------------------------------------------------LREYDWARALRFSLFGALYVAPTLYGWVRLTSAMWPQTNLRT---GIVKAITEQLSYGPFACVSFFMGMS-LLELKTFSQAVEETKEKAAPTYKVGVCIWPILQTINFSLVPEHNRVVFVSICSLMWTIFLAYMKTHHEE---QSNSAVLPCT------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W587-1", "uniprot_id": "Q9W587_DROME", "id": "Q9W587-1", "name": "Protein sym1", "aln": "-------------------------MAGPLLWQNFKVFVTR----------------------------------------YPIMRGMISYSLIWPTGSLIQQTVEGRR-----------------------------------------------------------------WGTYDWWRVLRFSMYGGLFVAPTLYGWVKISSAMWPQTSLRT---GVIKAAVETISYTPGAMTCFYFIMS-LLESKTVEQAVAEVGKKFLPTYKVALSVWPLVATINFTLIPERNRVPFISACSLCWTCFLAYMKHLEHH---EVDGAI----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VN75-1", "uniprot_id": "Q9VN75_DROME", "id": "Q9VN75-1", "name": "", "aln": "------------------------------MFRSLVNITSK----------------------------------------YKVLRGMISYGTLWPCGSLIEQTMIEKKT----------------------------------------------------------------FRTYDWMKCLRFSLFGFFFMGPTIYVWIRLASVMWPRTDIKS---SLCKAITEQTAYDPMAISSFLFFMT-LMEGNSYAEAKREVSDKFLDAYKVGVIYWPCVQTVNFAFVPARNQVVFTSFFSMCWTTFLAYVKFLQLHPPVDVDHHALDIHFLEM--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JNT1-1", "uniprot_id": "A8JNT1_DROME", "id": "A8JNT1-1", "name": "Mpv17-like protein", "aln": "------------------------------MARLISGVRNLFH-------------------------------------RYPFVTNSAIYGSLYVGAEYSQQFASKRWLAT-----------------------------------------------------------ASKPEDIDYATIGRYAVMGTAVYAPTLYLWYKWLDRAFPGTTKVI---IVKKLVLDQFVLTPYLLTVFYAGMS-IMEGS--ADIFLELREKFVPTFMRSCIFWLPAQALNFSLVAPRFRVIYMGICGLIWVNILCWTKRQSLPVATKEIATDSNNNAAAIRNSET---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08743-1", "uniprot_id": "YO292_YEAST", "id": "Q08743-1", "name": "Vacuolar membrane protein YOR292C", "aln": "MPLQLFGRDQIVVHYDNGNMSNDDQNHQSVLGSWTRRAAAALRTLMNKRIQRITLTHWLLLVIWVTSLWKFTSHYRQLYANSAVFATLCTNILLFGISDILAQSIACFYSYHVDPIPQILNDTFHHVQNNRDVENGGGYESDELSIFNDFTSEHSSYTDNDDYPELDRPLATFKTDTFDFFRWGCFMFWG-FFISFFQAPWYKFLNFFYTEDPTVVQ--VFERVLSDQLLYSPISLYCFFMFSNYVMEGGDKDTLGKKIQRLYISTLGCNYLVWPMVQFINFLIMPRDFQAPFSSSVGVVWNCFLSMRNASK---------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. * . . . : : * : : . ** : : : . : . . ", "identical_positions": 4, "similar_positions": 18, "identity": "1.16%" }, { "cls_id": "homologset.agr.SGD:S000005819", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63326-1", "uniprot_id": "RS10_RAT", "id": "P63326-1", "name": "Small ribosomal subunit protein eS10", "aln": "MLMPKKNRIAIYELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQSLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLHLP-----------PEIVPATLRR-SRPETGRPRPK-GPEGERPARFTRGEADRDTYRRSAVPPGADKKAEAGAGSATEFQFRGGFGRGRGQPPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63325-1", "uniprot_id": "RS10_MOUSE", "id": "P63325-1", "name": "Small ribosomal subunit protein eS10", "aln": "MLMPKKNRIAIYELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQSLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLHLP-----------PEIVPATLRR-SRPETGRPRPK-GPEGERPARFTRGEADRDTYRRSAVPPGADKKAEAGAGSATEFQFRGGFGRGRGQPPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46783-1", "uniprot_id": "RS10_HUMAN", "id": "P46783-1", "name": "Small ribosomal subunit protein eS10", "aln": "MLMPKKNRIAIYELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQSLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLHLP-----------PEIVPATLRR-SRPETGRPRPK-GLEGERPARLTRGEADRDTYRRSAVPPGADKKAEAGAGSATEFQFRGGFGRGRGQPPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NQ39-1", "uniprot_id": "RS10L_HUMAN", "id": "Q9NQ39-1", "name": "Putative ribosomal protein eS10-like", "aln": "MLMPKKNRIAIHELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQSLKSRGCVKEQFAWRHFYWYLTNEGSQYLRDYLHLPPEIVPATLHLPPEIVPATLHR-SRPETGRPRPK-GLEGKRPARLTRREADRDTYRRCSVPPGADKKAEAGAGSATEFQFRGRCGRGRGQPPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A5N7-1", "uniprot_id": "D4A5N7_RAT", "id": "D4A5N7-1", "name": "Small ribosomal subunit protein eS10", "aln": "MLMPKKNQIAIYELLFKEGVMDAQKDIHVPKHPELADKNVPNLHVTKAMQSLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLYLP-----------PEIVPATLSR-SRPETGRPRPK-GAEGERPARFTRGETD--TYRGELCPPGADKKAEAGAGSATEFLFREGFGHRCGQPPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VB14-1", "uniprot_id": "RS10A_DROME", "id": "Q9VB14-1", "name": "Small ribosomal subunit protein eS10A", "aln": "MFIPKANRVAIYEYLFKEGVLVAKKDSPIQKHSELDK--IPNLQVIKVMQSLNSRGWVKEQFAWRHFYWLLTNEGIEELRRYLHLP-----------PEIVPSTLTQTTRSNAVRPRGGPGGPGGGFGGASKTDDDRSNYRRGPGAYGMDKKGDVGAGTG-RVEYRGGFGRASRYDN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWG3-1", "uniprot_id": "RS10B_DROME", "id": "Q9VWG3-1", "name": "Small ribosomal subunit protein eS10B", "aln": "MFMPKAHRVAIYEYLFKEGVIVAKKDFHAQKHPELES--IPNLHVIKAMQSLHSRGLVKEQFAWRHYYWYLTNEGIEELRSYLHLP-----------PEIVPSTLKRPARSETVRPRPAVGGPRG-PGDASKTGEDRSAYRRAPGGSGVDKKGDVGPGAG-EVEFRGGFGRGSRN---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08745-1", "uniprot_id": "RS10A_YEAST", "id": "Q08745-1", "name": "Small ribosomal subunit protein eS10A", "aln": "MLMPKEDRNKIHQYLFQEGVVVAKKDFNQAKHEEIDT---KNLYVIKALQSLTSKGYVKTQFSWQYYYYTLTEEGVEYLREYLNLP-----------EHIVPGTYIQ-ERNPTQRPQRR--------------------Y--------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::** .: *:: **:***: *:** ** *: ** * *.:*** *:* ** **:*:::*: **:** : ** ** ** .***.* : * : **: * ", "identical_positions": 48, "similar_positions": 25, "identity": "26.97%" }, { "cls_id": "homologset.agr.SGD:S000005820", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1A5P2-1", "uniprot_id": "RRS1_RAT", "id": "A1A5P2-1", "name": "Ribosome biogenesis regulatory protein homolog", "aln": "MEGQSVEELLAKAKQEEAEKLQRITVHKELELEFDLGNLLASDRNPP--TVLRQAGPSPEAELRALARDNTQLLVNQLWQLPTERVEEAVVAR-----------LPEPATRLPREKPLPRPRPLTRWQQFARLKGIRPKKKT-NLVWDEVSGQWRRRWGYKRAR-DDTKEWLIEVPGSADPMEDQFAKRIRAKKERVAKNELNRLRNLARAHKMQMPSSAGLHPTGHQSKEELGRAMQVAKVSTASVGRFQERLPKEKAPRGSGKKR-----KFQPLFGDFAAEKKNQLELLRVMNSKKPQLDVTRATNKQMREEDQEEAAKRRKMSQKGKKKGGRQGPSGRRKGGPPSQGEKRKGVLGGKKHSRPPALGGKKKGVPHHGGKRRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CYH6-1", "uniprot_id": "RRS1_MOUSE", "id": "Q9CYH6-1", "name": "Ribosome biogenesis regulatory protein homolog", "aln": "MEGQRVEELLAKAEQEEAEKLQRITVHKELELEFDLGNLLASDRNPP--TVLRQAGPSPEAELRALARDNTQLLINQLWRLPTERVEEAVVAR-----------LPEPATRLPREKPLPRPRPLTRWQQFARLKGIRPKKKT-NLVWDEASGQWRRRWGYKRAR-DDTKEWLIEVPGSADPMEDQFAKRTQAKKERVAKNELNRLRNLARAHKMQMPSSAGLHPTGHQSKEELGRAMQVAKVSTASVGRFQERLPKEKAPRGSGKKR-----KFQPLFGDFAAEKKNQLELLRVMNSKKPRLDVTRATNKQMREEDQEEAAKRRKMSQKGKRKGGRQGPSGKRKGGPPGQGEKRKGGLGSKKHSWPSALAGKKKGVPPQGGKRRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15050-1", "uniprot_id": "RRS1_HUMAN", "id": "Q15050-1", "name": "Ribosome biogenesis regulatory protein homolog", "aln": "MEGQSVEELLAKAEQDEAEKLQRITVHKELELQFDLGNLLASDRNPP--TGLRCAGPTPEAELQALARDNTQLLINQLWQLPTERVEEAIVAR-----------LPEPTTRLPREKPLPRPRPLTRWQQFARLKGIRPKKKT-NLVWDEVSGQWRRRWGYQRAR-DDTKEWLIEVPGNADPLEDQFAKRIQAKKERVAKNELNRLRNLARAHKMQLPSAAGLHPTGHQSKEELGRAMQVAKVSTASVGRFQERLPKEKVPRGSGKKR-----KFQPLFGDFAAEKKNQLELLRVMNSKKPQLDVTRATNKQMREEDQEEAAKRRKMSQKGKRKGGRQGPGGKRKGGPPSQGGKRKGGLGGKMNSGPPGLGGKRKGGQRPGGKRRK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8I937-1", "uniprot_id": "Q8I937_DROME", "id": "Q8I937-1", "name": "Ribosome biogenesis regulatory protein", "aln": "MD--VVKEVLAKH-QKELDKYKPITVEKHLECRLDVGSLLITDPND---FDDRELRDNKEEYLTALTRENTQLLVNAIWELPTERVDESIVAK-----------LPEPTTVLPRLRKPPGPRPLTKWEKFAKEKGISKKKKD-KKTYDETMDKWVPTYGFKRAEAEKAKDWVLEVPQNADPNTDMFQKKIDLRNEKVAKNEIQRMKNIVRAKKIDMPRSGYLGPEAASS-SQLLTAVTVAKSSTASVGKFQNKLPKEKEARGLGIKELIPGGKRKQSHITQTPEKEANLDLIKSVLNKKPKLDVSKAVSMEKRDNRLAREAEAE--NEPGK-KGGKK-PKG--KGSRKAVGKKSKGNRGQRAP-------GKK---AQAGRKRR-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08746-1", "uniprot_id": "RRS1_YEAST", "id": "Q08746-1", "name": "Regulator of ribosome biosynthesis", "aln": "-------------MSAEDYKNLPVTVEKPIPVVYDLGNLAAFDSNVLDKNDLDSSNARREEKIKSLTRDNVQLLINQLLSLPMKTTTESVGGTGGQSSVMTLLQLPDPTTDLPREKPLPKAKAMTKWEKFAAKKGIKPKERAGKMIYDEASGEWVPKWGYKGANKKLDDQWLVEVDD----------------KVKGTDNELIDPRTLNRAERKRLVK----------------------KNEKQQRRNMKNAL-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * :**.* : *:*.* * * * : :*:*:*.***:* : ** : . *:: . **:*:* *** : * .:.:*:*::** *** *:: : :**. .:* :*:: *. . .:*::** : : :.**: :.: **.: : * .. . .::: * ", "identical_positions": 51, "similar_positions": 62, "identity": "13.25%" }, { "cls_id": "homologset.agr.SGD:S000005821", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VZY0-1", "uniprot_id": "Q9VZY0_DROME", "id": "Q9VZY0-1", "name": "", "aln": "MSDISSEDLRREIQAVLKDADLATISAKRVREQVEGKLNCSLLSRKKEFDKIV---MEVINEQQDEEDEDDDEGKDPDADPDDESEPSEEEDPSSSEEEAAKKKKQSPKKRPQPTKHKAPKKKRKTLNADDSGTESDAGSDSDYEVVKKPAAKKKAKAAGGTGSGRKSTGFTRAYNLSPELSALMGESSLPRHEVVKKVWAIIKERDLYDPKNKQFAICDDELMKVMKIRRFRTFGMLKHLKPHFLD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08747-1", "uniprot_id": "UAF30_YEAST", "id": "Q08747-1", "name": "Upstream activation factor subunit UAF30", "aln": "MAELN--DYSTMIDILLSDMDLETVTTKKVRMALKEVYAIDVESQGKAINKLIRKHLDLVKERPRFERSLEDLLKENATLAIELTKEITVSKRSSGEEKNDSETKGTHVEKKKGTVSKSPISTRKVTLSKSLASLLGEHELTRTEVVRRLWAYIKAHNLQNPNN-------KKEILCDEKLELILGKS--------TNMFEMHKILASHMTEPKKISDCPPLIQEVRRKEKPIVSDSEQSDTKGI--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:::. * *: :*.* ** *:::*:** :: .: *: * ::*:: :::::*: * . :* *: : . : :: .. **.**: .:.* : :: : * *:* ..**. :.. .: . . : ***:: * **: .... .: . :*. ::*:* .::: : * : .: *::: * : :* : .: . . : . : ", "identical_positions": 41, "similar_positions": 93, "identity": "16.6%" }, { "cls_id": "homologset.agr.SGD:S000005823", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PCT8-1", "uniprot_id": "DHSD_RAT", "id": "Q6PCT8-1", "name": "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial", "aln": "--MAVLLKLGVLCSGQ---------GARALSLR-SRAVRP--AFVSAFLQDQPTPGWRGTQHIHLSPSHQ-----SGSKAASLHWTSERVVSVLLLGLIPAGYLNP------CSVVDYSLAAALTLHSHWGIGQVVTDYVH----GDALQKATKAGLLAVS---ALTFAGLCYFNYHDVGICRAVAMLWKL-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CXV1-1", "uniprot_id": "DHSD_MOUSE", "id": "Q9CXV1-1", "name": "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial", "aln": "--MAVLLKLGVLCSGQ---------GARALLLR-SRVVRP--AYVSAFLQDQPTQGRCGTQHIHLSPSHH-----SGSKAASLHWTSERVVSVLLLGLIPAGYLNP------CSVVDYSLAAALTLHSHWGLGQVVTDYVH----GDTLPKAARAGLLALS---ALTFAGLCYFNYHDVGICRAVAMLWKL-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14521-1", "uniprot_id": "DHSD_HUMAN", "id": "O14521-1", "name": "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial", "aln": "--MAVLWRLSAVCGAL---------GGRALLLR-TPVVRP--AHISAFLQDRPIPEWCGVQHIHLSPSHH-----SGSKAASLHWTSERVVSVLLLGLLPAAYLNP------CSAMDYSLAAALTLHGHWGLGQVVTDYVH----GDALQKAAKAGLLALS---ALTFAGLCYFNYHDVGICKAVAMLWKL-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q68FN7-1", "uniprot_id": "DHSDB_DANRE", "id": "Q68FN7-1", "name": "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit B, mitochondrial", "aln": "--MAALVRISSLCHR----------GVSPLLFRPSSLIRP--LAVQ---QKDHDCSYLISARIHATPSNYA---GSGSKAATMHWTGERILSIALLSLAPVAYFCP------SPAVDYSLAAALTLHGHWGLGQVVTDYVH----GDAKIKMANAGLFVLS---TVTFAGLCYFNYHDVGICKAVALLWSK-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6DGM2-1", "uniprot_id": "DHSDA_DANRE", "id": "Q6DGM2-1", "name": "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit A, mitochondrial", "aln": "--MASLIRLSSVWQR----------GMRPVLLCHTQLSRG--SACPRIGDVDYTEP---AGRIHTASSST-------GISASQHWTGERVMTLVLLGMAPAAYLCP------GPVVDYSIAAALTMHGHWGIGQVLTDYVH----GEVKIKLAKVGIFLLS---TATFFGLCYFNYNDVGLCKAVVMLWQK-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCI5-1", "uniprot_id": "DHSD_DROME", "id": "Q9VCI5-1", "name": "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial", "aln": "MSLSLLLRGAVRCNAANLVKSARITPLKSYSTLVANVQRK--AVVQPLAVAKIVAPVVREISVSAPRMAS------AGSSHTLLWTVERIVSAGLLAVIPAAFIAP------SQVLDALMAISVVIHTHWGVEAMVVDYMRPSVVGNVLPKVAHIALIIIS---VATLGGLFYFIQNDVGLANGIKRFWAIKGKDAEKA---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08749-1", "uniprot_id": "TIM18_YEAST", "id": "Q08749-1", "name": "Mitochondrial import inner membrane translocase subunit TIM18", "aln": "--MLLFPGLKPVLNASTVIVN----PVRAVFPGLVLSTKRSFYSINRLNAENKINDIANTSKEASSSVQMFKPPEFSQFKDSYQKDYERIAKYTLIPLTMVPFYASFTGGVINPLLDASLSSIFLIYLQYGFTSCIIDYIP----KEKYPRWHKLALYCLYGGSMLSLYGIYELETKNNGFVDLVKKLWNENDDHLYIFGRN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : . : **: . *: : . : . :* :: . :: ::*. : **: : : . .: : :: *: : :: *: : :* ", "identical_positions": 10, "similar_positions": 39, "identity": "4.95%" }, { "cls_id": "homologset.agr.SGD:S000005827", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZY40-1", "uniprot_id": "A0A8I5ZY40_RAT", "id": "A0A8I5ZY40-1", "name": "A-kinase anchor protein 10, mitochondrial", "aln": "MRGAGPSPRHSPRALRPDPGPAMSFFRRKVKGKEQEKNLDVKSIKASIAVHSPQKSTKNHALLEAAGPSHVAINAISANMDSFSSSRTATLKKQPSHMEAAHFGDLGRSCLDYQTQETKSSLSKTLEQVLRDSVVLPYFLQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQSSLAEPVSPSKKQETTASFVTESLDRRLGDSSSAPLLLTQSEGTDLSSRTQNTQNHLLLSQECHSTHSLHHEVARTGTHQISTDSQESSSRLAVASRNSCSSPLRELSEKLMKSIEQDAVNTFTKYISPDAAKPIPITEAMRNDIIAKICGEDGQ-----VDPNCFVLAQAVVFSAMEQEHFSEFLRSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKG-QYDGQEAQNDAMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDLIHSVRG---DEFLGGNVSLAAHG------------SVCLPEESHSGGSDGSTAQSSVKKASIKILKNFDEAIVVDAASLDPESLYQRTYAGKMSFGRVSDLGQFIRESEPEPDVKKSK--------GFMFSQAMKKWVQGNTDEAQEELAWKIAKMIVSDVMQQAHHDQPLEKSTKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88845-1", "uniprot_id": "AKA10_MOUSE", "id": "O88845-1", "name": "A-kinase anchor protein 10, mitochondrial", "aln": "MRGAGPSPRHSPRALRPDPGPAMSFFRRKVKGKEQEKTLDVKSTKASVAVHSPQKSTKNHALLEAAGPSHVAINAISANMDSFSSSRTATLKKQPSHMEAAHFGDLGRSCLDYQTQETKSSLSKTLEQVLRDTVVLPYFLQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQSSLAEPVSPSKRHETPASSVTEALDRRLGDSSSAPLLVTQSEGTDLSSRTQNPQNHLLLSQEGHSARSLHREVARTGSHQIPTDSQDSSSRLAVGSRNSCSSPLRELSEKLMKSIEQDAVNTFTKYISPDAAKPIPITEAMRNDIIAKICGEDGQ-----VDPNCFVLAQAVVFSAMEQEHFSEFLRSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKG-QYDGQEAQNDAMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDLIHSVRG---DEFLGGNVSLAAHG------------SVCLPEESHSGGSDGSTAQSSVKKASIKILKNFDEAIIVDAASLDPESLYQRTYAGKMSFGRVSDLGQFIRESEPEPDVKKSK--------GFMFSQAMKKWVQGNTDEAQEELAWKIAKMIVSDVMQQAHHDQPLEKSTKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43572-1", "uniprot_id": "AKA10_HUMAN", "id": "O43572-1", "name": "A-kinase anchor protein 10, mitochondrial", "aln": "MRGAGPSPRQSPRTLRPDPGPAMSFFRRKVKGKEQEKTSDVKSIKASISVHSPQKSTKNHALLEAAGPSHVAINAISANMDSFSSSRTATLKKQPSHMEAAHFGDLGRSCLDYQTQETKSSLSKTLEQVLHDTIVLPYFIQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQSSLAEPVSPSKKHETTASFLTDSLDKRLEDSGSAQLFMTHSEGIDLNNRTNSTQNHLLLSQECDSAHSLRLEMARAGTHQVSMETQESSSTLTVASRNSPASPLKELSGKLMKSIEQDAVNTFTKYISPDAAKPIPITEAMRNDIIARICGEDGQ-----VDPNCFVLAQSIVFSAMEQEHFSEFLRSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKG-QYDGQEAQNDAMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDLIHSVRG---DEFLGGNVSLTAPG------------SVGPPDESHPGSSDSSASQSSVKKASIKILKNFDEAIIVDAASLDPESLYQRTYAGKMTFGRVSDLGQFIRESEPEPDVRKSK--------GSMFSQAMKKWVQGNTDEAQEELAWKIAKMIVSDIMQQAQYDQPLEKSTKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3I3-1", "uniprot_id": "Q9V3I3_DROME", "id": "Q9V3I3-1", "name": "", "aln": "--MLNYIKRHASRRRSSQDATDAICGQMPAYDVDTN---DVAGAGDAANAHKRHSLRSTTSFCDEVFLEAEEEGGVGTTGGGGGGGGGGGGGGAPSDGISLASNDD--------IFTYNSRLSMNLASIVNDPNCLSYFVQYLDTRQALPLIKFYLDIENFKRAALTQEKE------------EPEEPPRK------------------------------AIEQSSPHKDDKDVPELKTLCD--LSMRKPLTDDEKSRIYAETNKQLNRQKSGTDS-------VLNAELSRASISDAIAIYQKYLIVNASLQVELPIVILAHISLLLCGRDKSECSKPIPASCFDEAREFVLEQLERDHVQGFLQSGYYSTYCLELIEGGSVNIYDVLNSELALFYFTEYLEQRQERECLEFWITAINFRKSFACGEEKEEDRKAAQSDAMIIYDKYFSLQSECRLWMSQKLRLRVEQAICAPN-EQWQAFDLALLVTAKYLEQKYFADFLKSHIFDNYVNELKVKRDNSTTHPNLQHTLSLRRAGKSSNGQQQRHRKTLSMSDCTHISQHN-TLLASMDQAPSKTALNHQSGNLNIDARQLTNPQLLWQRPVGALKFGFVNSLGRYERDFEAVDAVALKSQPWSLSVSGSKLKNAMRKLVNLPEDNVQEEIAWQVAEMIVRDVTSVTLSGKTPPLA---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08760-1", "uniprot_id": "RAX1_YEAST", "id": "Q08760-1", "name": "Bud site selection protein RAX1", "aln": "------MKEELSKVSSMQNFEMIQRERLPTLY--------------EVLIQRTSQPVDLWTFYTFLSQFPYAINYLDFWVD----------------------------------LMTHTRLCKNYIELVRKS--LINFPQEQQQNGSTSTATFDLLNALIEEGHLD-----------------PEAPDKLLE------------------------------NSGPDVPFSPKLNELLGDWKHQSGIGQEALRNEDVALIVDEIMKRRSQQDGKPQ--------ITTKQLLHSAVGLCNTYLVSPEQSERYLSNIPMETRNRIIESVQIERKY------DIEIFDDLKNLTYQFLEMDCFPKFLSR-------------------------------VALHNIHDEISDWRFHSVGVTNEKSNRSRGQTHISRSPFSNHTSISRIGFGLLWLGIGFWIGYVLIFLAYS----------RAIRVVTVVPFTLGCYCIVCGMYQVDIVYSWFGVTQRLLHR-------------------------------------HKNAGNDEGDASSDTDHVPMILAVFGGRRRLTRIEHPFTRQLLRKRGLWCLLLVVGATAAFTVIFSCVPGRRV-------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .: : : . : . . :: . :. . :: *. . .::... * * * : . .* * :. * * : : . . * . .: : : . .. . :. : . : . :. * : . . * : .. . :* : . ** : .: . .* .. . ... . . . . ...: * : * : :. : : . ..: . . . .: . .: .:.. * . : * * . : . : : *. . : . ", "identical_positions": 21, "similar_positions": 114, "identity": "3.04%" }, { "cls_id": "homologset.agr.SGD:S000005831", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZQQ5-1", "uniprot_id": "A0A8I5ZQQ5_RAT", "id": "A0A8I5ZQQ5-1", "name": "", "aln": "--MSSTAEPPPPPPPESAPSKPSAAGA-GGSSSGNKGGPEGGAAPAAPSATGAGPADTEMEEVFDDGSPGKQ-KEIQEPDPTYEEKMQ-----TDRANRFEYLLKQTELFAHFIQPAAQKTPTSPLKMKPGRPRV-KKDEKQNLLSVGDYRHRRTEQEEDEELLT----ESSKATNVCTRFEDSPSYVKWGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKRWVPTLRSVCLIGDKEQRAAFVRDVLLPGEWDVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQ-KLVERLHMVLRPFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSAG--KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGRLVDQNLNKIGKDEMLQMIRHGATHVFASKESEIT-DEDIDGILERGAKKTAEMNEKLSKMGESSLRNFTMDT-----ESSVYNFEGEDYREKQKIAFT-EWIEPPKRERK---ANYAVDAYFREALR------VSEPKAPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVP--------RSPDLP---------NAAQAQ------------KEEQLKIDEAGPLNDEELEEKEKLLTQGFTNWNKRDFNQFIKANEKWGRDDIENIAREVEGKTPEEVIEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDTKIGRYKAPFHQLRISYGTNKGK-NYTEEEDRFLICMLHKLGFDKENVYDELRQCIRNSPQFRFDWFLKSRTAMELQRRCNTLITLIERENMELEEKEKAEKKKRGP--KPSTQKRKMDGAPDGRGRKKKLKL--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZW3-1", "uniprot_id": "SMCA5_MOUSE", "id": "Q91ZW3-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "aln": "--MSSAVEPPPPPPPESAPSKPSAAGA-GGSSSGNKGGPEGGAAPAAPCAAGSGPADTEMEEVFDHGSPGKQ-KEIQEPDPTYEEKMQ-----TDRANRFEYLLKQTELFAHFIQPAAQKTPTSPLKMKPGRPRV-KKDEKQNLLSVGDYRHRRTEQEEDEELLT----ESSKATNVCTRFEDSPSYVKWGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKKWVPTLRSVCLIGDKEQRAAFVRDVLLPGEWDVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQ-KLVERLHMVLRPFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSAG--KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGRLVDQNLNKIGKDEMLQMIRHGATHVFASKESEIT-DEDIDGILERGAKKTAEMNEKLSKMGESSLRNFTMDT-----ESSVYNFEGEDYREKQKIAFT-EWIEPPKRERK---ANYAVDAYFREALR------VSEPKAPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVP--------RSPDLP---------NAAQAQ------------KEEQLKIDEAEPLNDEELEEKEKLLTQGFTNWNKRDFNQFIKANEKWGRDDIENIAREVEGKTPEEVIEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDTKIGRYKAPFHQLRISYGTNKGK-NYTEEEDRFLICMLHKLGFDKENVYDELRQCIRNSPQFRFDWFLKSRTAMELQRRCNTLITLIERENMELEEKEKAEKKKRGP--KPSTQKRKMDGAPDGRGRKKKLKL--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60264-1", "uniprot_id": "SMCA5_HUMAN", "id": "O60264-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "aln": "--MSSAAEPPPPPPPESAPSKPAASIASGGSNSSNKGGPEGVAAQAVASAASAGPADAEMEEIFDDASPGKQ-KEIQEPDPTYEEKMQ-----TDRANRFEYLLKQTELFAHFIQPAAQKTPTSPLKMKPGRPRI-KKDEKQNLLSVGDYRHRRTEQEEDEELLT----ESSKATNVCTRFEDSPSYVKWGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKRWVPTLRSVCLIGDKEQRAAFVRDVLLPGEWDVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQ-KLVERLHMVLRPFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSAG--KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGRLVDQNLNKIGKDEMLQMIRHGATHVFASKESEIT-DEDIDGILERGAKKTAEMNEKLSKMGESSLRNFTMDT-----ESSVYNFEGEDYREKQKIAFT-EWIEPPKRERK---ANYAVDAYFREALR------VSEPKAPKAPRPPKQPNVQDFQFFPPRLFELLEKEILFYRKTIGYKVP--------RNPELP---------NAAQAQ------------KEEQLKIDEAESLNDEELEEKEKLLTQGFTNWNKRDFNQFIKANEKWGRDDIENIAREVEGKTPEEVIEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDTKIGRYKAPFHQLRISYGTNKGK-NYTEEEDRFLICMLHKLGFDKENVYDELRQCIRNSPQFRFDWFLKSRTAMELQRRCNTLITLIERENMELEEKEKAEKKKRGP--KPSTQKRKMDGAPDGRGRKKKLKL--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PGB8-1", "uniprot_id": "SMCA1_MOUSE", "id": "Q6PGB8-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1", "aln": "MEPDTATEAATVAVSDARATVVVVEDEQPGPSTFKEEGAAAAATEGTTATEKGEKK-EKITSPFQLKLAAKASKSEKEMDPEYEEKMVNMPLKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSPLNMKLARPRV-KKDDKQSLISVGDYRHRRTEQEEDEELLS----ESRKTSNVCVRFEVSPSYVKGGPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDVRAAFIRDEMMPGEWDVCVTSYEMVIKEKSVFKKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKNCLGDQ-KLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLSKMQREWYTKILMKDIDVLNSSG--KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEHIVGNSGKMVALDKLLARIKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYSRLDGQTPHEEREEAIDAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKLAKEEMLQMIRHGATHVFACKESELT-DEDIVTILERGEKKTAEMNERMQKMGESSLRNFRMDL-----EQSLYKFEGEDYREKQKLGTV-EWIEPPKRERK---ANYAVDAYFREALR------VSEPKIPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVP--------RNPEIP---------NPAIAQ------------REEQKKIDGAEPLTPQETEEKDKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSPEEVMEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTSKGK-NYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLISLIEKENMEIEERERAEKKKRAT--KTPMVKFSAFS---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5YCJ3-1", "uniprot_id": "A0A8I5YCJ3_RAT", "id": "A0A8I5YCJ3-1", "name": "", "aln": "MEPDTATEAATVAASDARATIVVLEDEQPGPSTFKEEGAAAAATEATTATEKGEKK-EKITSPFQLKLAAKTSKSEKEMDPEYEEKMVNIPLKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSPLNMKLARPRV-KKDDKQSLISVGDYRHRRTEQEEDEELLS----ESRKTSNVCVRFEVSPSYVKGGPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNFPGPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDVRAAFIRDEMMPGEWDVCVTSYEMVIKEKSVFKKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKNCLGDQ-KLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLSKMQREWYTKILMKDIDVLNSSG--KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEHIVSNSGKMVALDKLLARIKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEEREEAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKLAKEEMLQMIRHGATHVFACKESELT-DEDIVTILERGEKKTAEMNERMQKMGESSLRNFRMDL-----EQSLYKFEGEDYREKQKLGTV-EWIEPPKRERK---ANYAVDAYFREALR------VSEPKVPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVP--------RNPELP---------NPAIAQ------------REEQKKIDGAEPLTPQESEEKDKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNVAREVEGKSPEEVMEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTSKGK-NYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLISLIEKENMEIEERERAEKKKRAT--KTPMIEEESHHKRTSLLFEEHVVRNSLVTRLSI-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28370-2", "uniprot_id": "SMCA1_HUMAN", "id": "P28370-2", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1", "aln": "MEQDTAAVAATVAAADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKGEKKKEKNVSSFQLKLAAKAPKSEKEMDPEYEEKMK-----ADRAKRFEFLLKQTELFAHFIQPSAQKSPTSPLNMKLGRPRI-KKDEKQSLISAGDYRHRRTEQEEDEELLS----ESRKTSNVCIRFEVSPSYVKGGPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMVIKEKSVFKKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKNCLGDQ-KLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLSKMQREWYTKILMKDIDVLNSSG--KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEHIVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEEREEAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKLAKEEMLQMIRHGATHVFASKESELT-DEDITTILERGEKKTAEMNERLQKMGESSLRNFRMDI-----EQSLYKFEGEDYREKQKLGMV-EWIEPPKRERK---ANYAVDAYFREALR------VSEPKIPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVP--------RNPDIP---------NPALAQ------------REEQKKIDGAEPLTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSPEEVMEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTSKGK-NYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLISLIEKENMEIEERERAEKKKRAT--KTPMVKFSAFS---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24368-1", "uniprot_id": "ISWI_DROME", "id": "Q24368-1", "name": "Chromatin-remodeling complex ATPase chain Iswi", "aln": "---MSKTDTAAVEATE--------------------ENSNETTSDAATSSSG-------------------------EKEAEFDNKIE-----ADRSRRFDFLLKQTEIFTHFMTNSA-KSPTKPK----GRPKK-IKD-KDKEKDVADHRHRKTEQEEDEELLA----EDS-ATKEIFRFDASPAYIKSGEMRDYQIRGLNWMISLYENGINGILADEMGLGKTLQTISLLGYLKHFKNQAGPHIVIVPKSTLQNWVNEFKKWCPSLRAVCLIGDQDTRNTFIRDVLMPGEWDVCVTSYEMCIREKSVFKKFNWRYLVIDEAHRIKNEKSKLSEILREFKTANRLLITGTPLQNNLHELWALLNFLLPDVFNSSEDFDEWFNTNTCLGDD-ALITRLHAVLKPFLLRRLKAEVEKRLKPKKEMKIFVGLSKMQRDWYTKVLLKDIDVVNGAG--KVEKMRLQNILMQLRKCTNHPYLFDGAEPGPPYTTDTHLVYNSGKMAILDKLLPKLQEQGSRVLIFSQMTRMLDILEDYCHWRNYNYCRLDGQTPHEDRNRQIQEFNMDNSAKFLFMLSTRAGGLGINLATADVVIIYDSDWNPQMDLQAMDRAHRIGQKKQVRVFRLITESTVEEKIVERAEVKLRLDKMVIQGGRLVDNRSNQLNKDEMLNIIRFGANQVFSSKETDIT-DEDIDVILERGEAKTAEQKAALDSLGESSLRTFTMDTNGEAGTSSVYQFEGEDWREKQKLNALGNWIEPPKRERK---ANYAVDAYFREALR------VSEPKAPKAPRPPKQPIVQDFQFFPPRLFELLDQEIYYFRKTVGYKVP--------KNTELGS--------DATKVQ------------REEQRKIDEAEPLTEEEIQEKENLLSQGFTAWTKRDFNQFIKANEKYGRDDIDNIAKDVEGKTPEEVIEYNAVFWERCTELQDIERIMGQIERGEGKIQRRLSIKKALDQKMSRYRAPFHQLRLQYGNNKGK-NYTEIEDRFLVCMLHKLGFDKENVYEELRAAIRASPQFRFDWFIKSRTALELQRRCNTLITLIERENIELEEKERAEKKKKAP--KGSVSAGSGSASSNTPAPAPQPKASQKRKSEVVATSSNSKKKKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08773-1", "uniprot_id": "ISW2_YEAST", "id": "Q08773-1", "name": "ISWI chromatin-remodeling complex ATPase ISW2", "aln": "-----MTTQQEEQRSDTKNSKSESPSEVLVDTLDSKSNGSSDDDNIGQSEELSDKEIYTVEDRPPEYWAQRKKKFVLDVDPKYAKQKD----KSDTYKRFKYLLGVTDLFRHFIGIKAKHDKNIQKLLKQLDSDANKLSKSHSTVSSSSRHHRKTEKEEDAELMADEEEEIVDTYQEDIFVSESPSFVKSGKLRDYQVQGLNWLISLHENKLSGILADEMGLGKTLQTISFLGYLRYVKQIEGPFLIIVPKSTLDNWRREFLKWTPNVNVLVLHGDKDTRADIVRNIILEARFDVLITSYEMVIREKNALKRLAWQYIVIDEAHRIKNEQSALSQIIRLFYSKNRLLITGTPLQNNLHELWALLNFLLPDIFGDSELFDEWFEQNNSEQDQEIVIQQLHSVLNPFLLRRVKADVEKSLLPKIETNVYVGMTDMQIQWYKSLLEKDIDAVNGAVGKREGKTRLLNIVMQLRKCCNHPYLFEGAEPGPPYTTDEHLIFNSGKMIILDKLLKRLKEKGSRVLIFSQMSRLLDILEDYCYFRDFEYCRIDGSTSHEERIEAIDEYNKPNSEKFVFLLTTRAGGLGINLVTADTVILFDSDWNPQADLQAMDRAHRIGQKKQVHVYRFVTENAIEEKVIERAAQKLRLDQLVIQQGTGKKTASLGNSKDDLLDMIQFGAKNMFEKKASKVTVDADIDDILKKGEQKTQELNAKYQSLGLDDLQKFNGIE-----NQSAYEWNGKSFQKKSNDKVV-EWINPSRRERRREQTTYSVDDYYKEIIGGGSKSASKQTPQPKAPRAPKVIHGQDFQFFPKELDALQEKEQLYFKKKVNYKVTSYDITGDIRNEGSDAEEEEGEYKNAANTEGHKGHEELKRRIEEEQEKINSAPDFTQEDELRKQELISKAFTNWNKRDFMAFINACAKYGRDDMENIKKSIDSKTPEEVEVYAKIFWERLKEINGWEKYLHNVELGEKKNEKLKFQETLLRQKIEQCKHPLHELIIQYPPNNARRTYNTLEDKFLLLAVNKYGLRADKLYEKLKQEIMMSDLFTFDWFIKTRTVHELSKRVHTLLTLIVREYEQPDANKKKRSRTSATREDTPLSQNESTRASTVPNLPTTMVTNQKDTNDHVDKRTKIDQEA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: . . : :. : :: :* .**.:** *::* **: * : . . . ... . .. :**:**:*** **:: * : : .. **:::* * :****::****:***:** :.****************::***::: :: **.:::******.** ** :* *.:. : : **:: * ::*: :: ..:** :***** *:**..:*:: *:*:***********:* **:*:* * : ****:*************:********:*..:: **.**: :.. *: :: :** **.******:*::*** * ** * ::::*::.** :**. :* **** :*.: : * ** **:****** ******:*********** *:: ***** ***** :::*:**********:*:******** :*.::*.*:**.*.*::* *: :* ** **:*:*:**********.:**.**::******* *************.* *:*:*::*:.::**:::*** *****.:*** * . *:::*::*:.**.::* * :.:* * ** **::* ** * : ..:* ..*:.* .* *:::*:.:::*.: :**:*.:***: :.*:** *::* : .:. *****.** ******* .* * ::* :::*.:.***. :. :.: .: .*** **: * :. :: .*::*:::.** *.**** **:* *:****::*: :.::.*:**** * :**** .*::. *: : ::* ** : :: :. * *: : : *:*:* :.* .:.: .*. **:**: ::* *: :::*::*: : : * ****:*:**. *:.:* :**::** :* : : .:: ..:. .. . . . ", "identical_positions": 417, "similar_positions": 322, "identity": "36.71%" }, { "cls_id": "homologset.agr.SGD:S000005833", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1AT66-1", "uniprot_id": "MOT7_MOUSE", "id": "B1AT66-1", "name": "Monocarboxylate transporter 7", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRASGQGPQRRRRGWATRDDSAVTFRDPQPRQPAGGARALRGPDPRGPARAHQAGPLLAGARRSQHMVGGAPPRPAETGCSRSRMTQKNSKLCARANVYTQVPDGGWG-WAVAVSFFFVEVFTYGIIKSFGVFFNDLMDSFDESNS-----KISWIISICVFVLTFTAPLSTVLSNRFGHRLVVMAGGLLISLGMITASFSQRVYHMYISIGVISGLG---YCFSFLPTVTILSQYFDKRRSVVTAVASTGECFAVFAFAPAITALK-------EHIGWRYSLLFVGLLQLNIMVCGALLRPIIIQGPGQSPKAVTLEP------------------------------------RREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKMEQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ETRAEQQQTLVTA-PKHSQMKAPLLDFSVLKE-KSFICYALFGLFATLGFFAPSLYIIPLGISLGIDPDR-AAFLLSTMAIAEVFGRIGAG-FVLNREPIR--KIYIEL-----ICVILLTASLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPMLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLV--DQSKIYSRAFYSCAAGMCLAAVCLALVRPCKKG----------LCQNSHSGENQTDRQRGKALQDIPEDF----------------------------LEMDLGKCEHRAHMKMDPV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TMR7-1", "uniprot_id": "MOT7_RAT", "id": "Q7TMR7-1", "name": "Monocarboxylate transporter 7", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQKNSKLCSRANVYTQVPDGGWG-WVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNS-----KISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLG---YCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALK-------EHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPG-SPKAIPLEP------------------------------------RREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EVRVEQQQTLVVG-PKHSQKRAPLLDFSILKD-RSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDR-AAFLLSTMAIAEVFGRIGMG-LVLNREPIR--KIYIEL-----ICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLV--DQSKIYSRAFYSCAAGMALAAVCLALVRPCKKG----------LCQNPHSGENQTDGHRGKALQDIPEDF----------------------------LEMDLGKCEPRAHMKMDPV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15403-1", "uniprot_id": "MOT7_HUMAN", "id": "O15403-1", "name": "Monocarboxylate transporter 7", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQNKLKLCSKANVYTEVPDGGWG-WAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNS-----RISWIISICVFVLTFSAPLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLG---YCFSFLPTVTILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALK-------ERIGWRYSLLFVGLLQLNIVIFGALLRPIFIRGPA-SPKIVIQEN------------------------------------RKEAQYMLENEKTRTSIDSIDSGVELTTSPKNVPTHTNLEL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EPKADMQQVLVKTSPRPSEKKAPLLDFSILKE-KSFICYALFGLFATLGFFAPSLYIIPLGISLGIDQDR-AAFLLSTMAIAEVFGRIGAG-FVLNREPIR--KIYIEL-----ICVILLTVSLFAFTFATEFWGLMSCSIFFGFMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQSIAGLAGPPLAGLLV--DQSKIYSRAFYSCAAGMALAAVCLALVRPCKMG----------LCQHHHSGETKVVSHRGKTLQDIPEDF----------------------------LEMDLAKNEHRVHVQMEPV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O70451-1", "uniprot_id": "MOT2_MOUSE", "id": "O70451-1", "name": "Monocarboxylate transporter 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSEP-----SAPLPQPLPPDGGWG-WVVVCASFISIGFSYAFPKAVTVFFKDIQEIFNTTSS-----QIAWISSIMLAVMYAGGPISSVLVNNYGSRPVVIVGGLLCCIGMILASYSNSVIELYLTVGFIGGLG---LAFNLQPALTIIGKYFYRRRPLANGCAMAGSPVFLSTLAPFNQYLF-------NNYGWKGSFLILGGIFLHSCVAGCLMRPVGPSP---NTKKSKS------------------------------------------KVGSRHD--STLKKASKVSTAQKVNR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FLDFSLFMH-RGFLIYLSGNVILFLGIFAPIIFLAQYAKHIGVDDYN-SAFLLSVMAFIDMFARPSVG-LIANTSLIRPRIQYLFS-----SAIIFTGICHLLCPLATTYSALVVYVVFFGLGFGSIS--SLLFECLMDIVGATRFSSAVGLTTIVECCPVLFGPPLAGKLL--DITGEYKYLYIASGTVVLVSGTYLLIGNAINY----------RLLDKERKREKAKKKKSASHASREMEAL-------NRSKQ-DEVT-----------VKASNAHNPPSDRDKESNI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63344-1", "uniprot_id": "MOT2_RAT", "id": "Q63344-1", "name": "Monocarboxylate transporter 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSESSVKATAAPPPFPLPPDGGWG-WVVVCASFISIGFSYAFPKAVTVFFNDIKDIFKTTSS-----QIAWISSIMLAVMYAGGPISSVLVNNYGSRPVVIVGGLLCCTGMILASFSSSVIELYLTVGFIGGLG---LAFNLQPALTIIGKYFYRKRPLANGFAMAGSPVFLSTLAPFNQFLF-------NSYGWKGSFLILGAIFLHSCVAGCLMRPVGPSP---RAAKSKS------------------------------------------KVGSRQD--SSTKRLSKVSTAEKINR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FLDFGLFTH-RGFLIYLSGNVVLFLGMFAPIIFLAPYAKDKGVDDYN-SAFLLSVMAFTDMFARPSVG-LIANTSLIRPRIQYLFS-----VAIMFTGICHLLCPLAHSYTALVVYVIFFGIGFGSIS--SLLFECLMDQVGASRFSSAVGLVTIVECCPVLFGPPLAGKLL--DITGQYKYLYIASGIVVLSSGIYLLICNAINY----------RLLEKERKREKARRKKSASQASKEMEAL-------SRSKQ-DDVT-----------VKVSNTHNPPSDRDKESSI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60669-1", "uniprot_id": "MOT2_HUMAN", "id": "O60669-1", "name": "Monocarboxylate transporter 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPMP-----SAPPVHP-PPDGGWG-WIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYS-----EIAWISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLG---LAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLF-------NTFGWKGSFLILGSLLLNACVAGSLMRPLGPNQ---TTSKSKN------------------------------------------KTGKTEDDSSPKKIKTKKSTWEKVNK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YLDFSLFKH-RGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYS-AAFLLSVMAFVDMFARPSVG-LIANSKYIRPRIQYFFS-----FAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVS--SVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLV--DLTGEYKYMYMSCGAIVVAASVWLLIGNAINY----------RLLAKERKEENARQK------TRESEPL-------SKSKHSEDVN-----------VKVSNAQSVTSER--ETNI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53986-1", "uniprot_id": "MOT1_MOUSE", "id": "P53986-1", "name": "Monocarboxylate transporter 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPAIG------GPVGYTPPDGGWG-WAVLVGAFISIGFSYAFPKSITVFFKEIEVIFSATTS-----EVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYLCIGVIGGLG---LAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFF-------DIFDWRGSFLILGGLLLNCCVAGSLMRPIGPEQVKLEKLKSKESL------------------------------------QEAGKSDANTDLIGGSPKGEKLSVFQTINK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FLDLSLFTH-RGFLLYLSGNVVMFFGLFTPLVFLSSYGKSKDFSSEK-SAFLLSILAFVDMVARPSMG-LAANTKWIRPRIQYFFA-----ASVVANGVCHLLAPLSTTYVGFCVYAGVFGFAFGWLS--SVLFETLMDLIGPQRFSSAVGLVTIVECCPVLLGPPLLGRLN--DMYGDYKYTYWACGVILIIAGIYLFIGMGINY----------RLLAKEQKAEEKQKREGKEDEASTDVDE-------KPKETMKAAQ-----------SPQ--QHSSGDPTEEESPV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53987-1", "uniprot_id": "MOT1_RAT", "id": "P53987-1", "name": "Monocarboxylate transporter 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPAIG------GPVGYTPPDGGWG-WAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTS-----EVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLG---LAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFF-------GIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESL------------------------------------QEAGKSDANTDLIGGSPKGEKLSVFQTVNK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FLDLSLFTH-RGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEK-SAFLLSILAFVDMVARPSMG-LAANTRWIRPRVQYFFA-----ASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLS--SVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLN--DMYGDYKYTYWACGVILIIAGLYLFIGMGINY----------RLVAKEQKAEEK-KRDGKEDETSTDVDE-------KPKKTMKETQ-----------SPAPLQNSSGDPAEEESPV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35308-1", "uniprot_id": "MOT3_MOUSE", "id": "O35308-1", "name": "Monocarboxylate transporter 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MG-------AGGPRRGAGPPDGGWG-WVVLGACFVVTGFAYGFPKAVSVFFRELKRDFGAGYS-----DTAWVSSIMLAMLYGTGPLSSILVTRFGCRPVMLAGGLLASAGMILASFASRLVELYLTAGVLTGLG---LALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSMLSPLGQLLG-------ERFGWRGGFLLFGGLLLHCCACGAVMRPPPGPP--------------------------------------------------------------PRRDPSPHGGPARRRR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLDVAVCTD-RAFVVYVVTKFLMALGLFVPAILLVNYAKDAGVPDAE-AAFLLSIVGFVDIVARPACG-ALAGLGRLRPHVPYLFS-----LALLANGLTDLISARARSYGTLVAFCIAFGLSYGMVG--ALQFEVLMATVGAPRFPSALGLVLLVEAVAVLIGPPSAGRLV--DALKNYEIIFYLAGSEVALAGVFMAVTTYCCLRCSKNISSGRSAEGGASDPEDVEAERDSEPMPASTEEP-------GSLEALEVLSPRAGSPEQEPEEEAVPELDHESIGGHEARGQKA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70461-1", "uniprot_id": "MOT3_RAT", "id": "O70461-1", "name": "Monocarboxylate transporter 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MG-------AGGPRRGAGPPDGGWG-WVVLGACFVITGFAYGFPKAVSVFFRELKRDFGAGYS-----DTAWVSSIMLAMLYGTGPLSSILVTRFGCRPVMLAGGLLASAGMILASFASRLLELYLTAGVLTGLG---LALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSTLSPLGQLLG-------ERFGWRGGFLLFGGLLLHCCACGAVMRPPPGPQ--------------------------------------------------------------PRPDPAPPGGRARHRQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLDLAVCTD-RTFMVYMVTKFLMALGLFVPAILLVNYAKDAGVPDAE-AAFLLSIVGFVDIVARPACG-ALAGLGRLRPHVPYLFS-----LALLANGLTDLISARARSYGTLVAFCIAFGLSYGMVG--ALQFEVLMATVGAPRFPSALGLVLLVEAVAVLIGPPSAGRLV--DALKNYEIIFYLAGSEVVLAGVFMAVTTYCCQRCSKDIPPGPSAEGGTSDTEDVEAERDSEPMPASTEEP-------GSLEALEVLSPRAGSPE--PEEEAVPDLSHESVGGHEAHGQNA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57787-1", "uniprot_id": "MOT4_MOUSE", "id": "P57787-1", "name": "Monocarboxylate transporter 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGAVV---DEGP-TGIKAPDGGWG-WAVLFGCFIITGFSYAFPKAVSVFFKELMHEFGIGYS-----DTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLG---LALNFQPSLIMLNRYFNKRRPIANGLAAAGSPVFLCALSPLGQLLQ-------DHYGWRGGFLILGGLLLNCCVCAALMRPLVAPQ--------------------------------------------------------------VGGGTEPRGPQRPPQR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLDLSVFRD-RGFLIYAVAASIMVLGLFVPPVFVVSYAKDMGVPDTK-AAFLLTILGFIDIFARPTAG-FITGLKKVRPYSVYLFS-----FAMFFNGFTDLTGSTATDYGGLVVFCIFFGISYGMVG--ALQFEVLMAIVGTQKFSSAIGLVLLLEAVAVLIGPPSGGKLL--DATKVYKYVFILAGAEVLTSSLVLLLGNFFCI--------GKRKRPEVTEPEEVASEE-KLHKPPVDVGV-------DSREVEHFLK-------------AEPEKNGEVVHTPETSV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35910-1", "uniprot_id": "MOT4_RAT", "id": "O35910-1", "name": "Monocarboxylate transporter 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGAVV---DEGP-TGIKAPDGGWG-WAVLFGCFIITGFSYAFPKAVSVFFKELMHEFGIGYS-----DTAWISSILLAMLYGTGPLCSMCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLG---LALNFQPSLIMLNRYFNKRRPMANGLAAAGSPVFLCALSPLGQLLQ-------DHYGWRGGFLILGGLLLNCCVCAALMRPLVAPQ--------------------------------------------------------------ASGGAEPHGPQRPSPR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLDLSVFRD-RGFLIYAVAASIMVLGLFVPPVFVVSYAKDMGVPDTK-AAFLLTILGFIDIFARPTAG-FITGLKKVRPYSVYLFS-----FAMFFNGFTDLTGSTASDYGGLVVFCIFFGISYGMVG--ALQFEVLMAIVGTQKFSSAIGLVLLLEAVAVLIGPPSGGKLL--DATKVYKYVFILAGAEVLTSSLVLLLGNFFCI--------GKRKRPEVTKPEEVASEEEKLHKPPVDVRV-------DSREVEHFLK-------------AEPEKNGEVVHTPETSV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G5E8K6-1", "uniprot_id": "MOT6_MOUSE", "id": "G5E8K6-1", "name": "Monocarboxylate transporter 6", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARALEQADGRWA-WVVLLSSLVTQALTLGFPTCIGVFFTDLQRDFQASNS-----ETSWFPSILGAMVHGGGPLCSILVKHFGCRVTMMLGGVLASLGMVVSTFSGSLTHLFLTAGVITGLG---MCFSFQSSITVVGLYFVRRRPLANALASMGLSMGVTLWPLLARYLL-------ETLGWRGAFLIFGGILLHCCVCGALLRPVATNEVPEPKEDPLL-------------------------------------------------PPKIPTRSCLATCVSTIRY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HLAFDILRHNMGFCIYVTGVTWMNLGFALPHIFLVPYAMHHGVDDYW-AAMLMSIVGFCNIFLRPMAGLLLAGRKSLAAYRKYLFA-----VAILINGLTNLICTVSADFRVLLGYCLVYSLSMCGVG--ILVFQVLMDIVPMDRFPSALGLFTILCGVTSLISPPLAGLLL--DKTNNFSYVFYMSSGFLVSGSLILGVGFYAAEKKK-------LKQDGQAKMENATSEMTPMHDLTSEDKD-------SAKKQP------------------------YPESIYMTNV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A3B5-1", "uniprot_id": "D4A3B5_RAT", "id": "D4A3B5-1", "name": "Monocarboxylate transporter 6", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQALEQADGRWA-WVVLLASLVTQALTVGFPSCIGVFFTDLQRDFQASNS-----ETSWFPSIMGAMLHCGGPLCSILIKRFGCRVTMMLGGVLASLGMVASTFSDSLIHLFLTAGLITGLG---MCFSFQSSITVVGLYFVRQRPLANALASIGISMGVTLWPLLARYLL-------ETLGWRGAFLIFGGIFLHCCVCGAMLRPVATNVDPEPKEDLLL-------------------------------------------------PPKTPTRSCLATCVSTIQY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YLAFDILRHNMVFCIYVTGATWMTLGFSLPHIFLVPYAMHHGMEEYW-AAMLMSIVGFCNIFLRPVAG-MLAGRKSLAAYRKYLFA-----VAILINGLTNLICTVSADFRVLLGYCLVYSLSMCGTG--ILVFQVLMDIVPMDRFPSALGLFTILCGMGSLISPPLAGLLL--DTTNNFNYVFYMSSGLLISASLFMGVGFYVAEKK--------LKQDRQAKMEDATSEITSKHSLTSEDKD-------SAKKQP------------------------YPENIYVTSV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15375-1", "uniprot_id": "MOT6_HUMAN", "id": "O15375-1", "name": "Monocarboxylate transporter 6", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQALERADGSWA-WVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNS-----ETSWFPSILTAVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLG---MCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLL-------ENLGWRGTFLVFGGIFLHCCICGAIIRPVATSVAPETKECPPP-------------------------------------------------PPETPALGCLAACGRTIQR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HLAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQ-AALLISIIGFSNIFLRPLAG-LMAGRPAFASHRKYLFS-----LALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIG--ALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLL--DATNNFSYVFYMSSFFLISAALFMGGSFYALQKK---------EQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWGCPASSRTSHEWLLWPKAVLQAKQTALGWNSPT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W509-1", "uniprot_id": "Q9W509_DROME", "id": "Q9W509-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVHG---PPARRKSQQQ-------HEACEMDMERQP-----------------------TPPDGGWG-WVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKG-----YTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLG---FGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLI-------GNYGWRGAMLIIGGIVLNCIIFGAMFRPL----------------------------------------------------ELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLP---------------------KDQYLQLPQRTDTAVSGGALCRS----NSVGHNLKPNLNNNSN----------GAVNGQGPTLVT------------PPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRE----RSASGTMYRP----DALYQGSLHNLPDYVSS------RNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEMMNFSLLKD-MVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTD-ASYLISTIGVANTVGRIILG-YISDKPWVN--RLLVYN-----VCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVG--LTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMY--DLTDSYAPAFLMAGLMIAIS--GLVMFAIPPLQR-----------LQVRKSERKPHTEHLALS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0L6-1", "uniprot_id": "Q9W0L6_DROME", "id": "Q9W0L6-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVDTNSSNPGIVGGNSASSARLRRFERTDSELACEEAARLTAEQSPEDEDNQDNDEDDDDEESVYGELPPPPDGGYG-WVICFASFMCNMIVDGIAYTFGIFLEEFVAYFHEGKG-----TVAWVGSLLSGVYLSAGPIVSALANKYGCRAVCIAGSIIACIAFVLSTFSTNVSMLMATYGFMGGFG---FGMIYLPAVVAVGYYFETKRSLATGIAVCGSGFGTFAFAPLATYLL-------EEYGWKNALLIFAGLILNCAIFGAMMRPLTYPKKKKQKPLMQRMYEEKQLQLERGSFAGSHFMVQLPDG------------TIERKLKMPLNADPGVHSSLNLELLAQQAGGGGLHPVSTLPTITESKVVDVHRQNGAQSPPNGDSNGQLSARSAAGAVGRRPHRNSESENSPYHSQDAMTRNASQPAFLAGDHQSLPKNGSVPAFNTRVRKTSASERFQPSLAAIRATSRGDLEAGAGGDFASSKLSLSQRQGGSQTGSSGRMVRPMSRKDIFYSGSVTNLPQYQSQKSLANYRNSVLSLTKYEKSMQSVAKLDPLAEAEKHREEYDLCPCLGIPDSVKSVVNTMLDVSLLKD-PVFMLIGVSNIFGMAGLYVPFVYLVDAAKEHDIPKND-AAMLLSIIGITNTVGRVFCG-WVADLPQVN--SLLLNN-----CCLLVSTIAVTLTPLCYSYAAYITMSIFFGLAISGYIS--LTSIILVDLLGLDKLTNAFGLLILFRGFAALIGTPLAGAIY--DMTHTYDLPFYMAGALFGIS--TITSFLAPCLKR-----------CSPSE-ETPVHVETLTPIDEEQGEDA---------------------------EDDEDQPITIVPKIIKTLASPQQEEGHPQFPQKTSESKL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8K1C7-1", "uniprot_id": "MOT14_MOUSE", "id": "Q8K1C7-1", "name": "Monocarboxylate transporter 14", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYTSHEDIGYDLEDDRKAKNKKTLKPH----------------------PDIDGGWA-WMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRG-----LTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVQSLFITFGVAAGLG---SGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLC-------AEYGWRNAMFIQGALSLNLCVCGALMRPLS-------------------------------------------------------PEKLENCPEAEEPCALPAYSTESVKSGGPLGMAEEQD--------------------------------------------------------------------------------------------------------RRPGNEE---------MVCDLQT--------------------------------------------------------QECQGQTHPRKNVCAFRVLKTVSQLTVQVRRGFRDWHSGYFGTASLFTN-RMFVAFIFWALFAYSSFVIPFIHLPEIVSLYNLSEQNDTFPLTSIIAILHIFGKVILG-AVADLPCIS--VWNVFL-----IANFTLVLSIFLLPLMHTYASLAVICALIGFSSG-YFS--LMPVVTEDLVGTEHLANAYGIIICANGISALLGPPFAGWIF--DITQKYDFSFYICGLLYMVG--ILFLLIQPCIQM-----------IDQSRRKCIEGAHV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A0E5-1", "uniprot_id": "D4A0E5_RAT", "id": "D4A0E5-1", "name": "Monocarboxylate transporter 14", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYTSHEDIGYDLEDDRKAKNKKTLKPH----------------------PDIDGGWA-WMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRG-----LTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVQSLFITFGVAAGLG---SGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLC-------AEYGWRNAMFIQGALSLNLCVCGALMRPLS-------------------------------------------------------PEKVENCSGAEEPCALPAYSTESVKSGGPLDMTEEQD--------------------------------------------------------------------------------------------------------RRPGNEE---------TVCDLQT--------------------------------------------------------QELQGQTHPRKNVCAFRVLKTVGQLTVRVQRGFRDWHSGYFGTASLFTN-RMFVAFIFWALFAYSSFVIPFIHLPEIVSLYNLSEQNDAFPLTSIIAILHIFGKVILG-AVADLPCIS--VWNVFL-----IANFTLVLSIFLLPLMHTYASLAVICALIGFSSG-YFS--LMPVVTEDLVGTEHLANAYGIIICANGISALLGPPFAGWIF--DITQKYDFSFYICGLLYMVG--ILFLLIQPCIQM-----------TEQSGRKCMDSAHV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TM99-1", "uniprot_id": "MOT9_MOUSE", "id": "Q7TM99-1", "name": "Monocarboxylate transporter 9", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEFQ----------------------KSPDGGWG-WVIVVVSFFTQFLSYGSPLAVGVLYVEWLDAFGEGKG-----KTAWVGSLASGVGLLASPVCSLFVSSFGARPVTIFSGFLVAGGLMLSSLAPNIYFLFFSYGIVVGLG---CGLLYTATVTITCQYFDSRRGLALGLISTGSSVGLFIYAALQRMLI-------EFYGLDGCLLIVGALALNILACGSLMRPLQ-------------------------------------------------------TSDCPFPEKTAPENVPDRYSMYNEKEKNPEETMNFQD--------------------------------------------------------------------------------------------------------KGYSSEDKCLPNGDWGRETSLPK--------------------------------------------------------SLAIAAHTKEPETYKKKVVEQTNFCKQLAKRKWQLYRNYCGETASLFKN-KVFSALFIAILLFDIGGFPPSLLMEDVARSYHVREEDLTMPLISIFGIMTAVGKLLLG-ILADFKWIN--TLYLYV-----ATLIITGLALCAIPFAKSYVTLAILSGILGFLTG-NWS--IFPYVTTKTVGIDKLAHAYGILMFFAGLGNSLGPPIVGWFY--DWTQTYDIAFYFSGFCVLLGGFILLLAILPCWDM-----------CNKKLPKPAVPTTFFYKVASNV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RCI4-1", "uniprot_id": "MOT9_RAT", "id": "M0RCI4-1", "name": "Monocarboxylate transporter 9", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGFQ----------------------KSPDGGWG-WVIVVVSFFTQFLCYGSPLAVGVLYVEWLDAFGEGKG-----KTAWVGSLASGVGLLASPVCSLFVSSFGARPVTIFSGFLVAGGLMLSSLAPNIYFLFFSYGIVVGLG---CGLLYTATVTITCQYFDSRRGLALGLISTGSSVGLFIYAALQRMLI-------EFYGLDGCLLIVGALALNILACGSLMRPLQ-------------------------------------------------------TSDCPFPEKIAPENVPDRYSIYNEKEKNQEETMTFQD--------------------------------------------------------------------------------------------------------KGYSNEDKCLPNGDWGRETSLPK--------------------------------------------------------NPTGAAHTKEPEPYKKKVVEQTNFCKQLAKRKWQVYRNYCGETASLFKN-KVFSALFVAILLFDIGGFPPSLLMEDVARSYHVREEDLTIPLISIFGIMTAVGKLLLG-ILADFKWVN--TLYLYV-----ATLIITGLALCAIPLAKSYVTLAILSGILGFLTG-NWS--IFPYVTTKTVGIDKLAHAYGILMFFAGLGNSLGPPIVGWFY--DWTQTYDIAFYFSGFCVLLGGFILLLAILPCWGM-----------CNQRLPKPAAPTTFFYKVASNV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGC3-1", "uniprot_id": "MOT12_MOUSE", "id": "Q8BGC3-1", "name": "Monocarboxylate transporter 12", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTKITRVSLAS-----------------------PPDGGWG-WMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDYS-----QTAWIHSIVDCMTMLCAPLGSVVSNQLSCQAGIMLGGLLASTGFILGSFATSLKHLYLSLGVLTGLG---FALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLI-------EQFSWRGALLILGGFVLNLCVCGALMRPIT------------------------------------------------------------LKEDRSVPE--KNHNRESQRE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DCKQASPYSPLTKECTETRLCCSLQQEYGFLLM-SDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHHQ-AAFLMSILGVIDIVGNITFG-WLTDRRCLKNYRYVCYL-----FAVALDGLCYLCLPMLQTFPLLVPFSCTFGYFDGAYVT--LIPVVTAEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGWLV--DTTGSYTAAFLLCGFAMIFSSILLGFVRIVKRMK-----------RTQVPFPVKDSDPKLQLWTNGSVAYS---------------------------VARELDQKDEEPLPKARSGCNLT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZSM3-1", "uniprot_id": "MOT12_HUMAN", "id": "Q6ZSM3-1", "name": "Monocarboxylate transporter 12", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSGSHWTANSSKIITWLLEQPGKEEKRKTMAKVNRARSTS-----------------------PPDGGWG-WMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYA-----QTAWIHSIVDCVTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTGLG---FALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLI-------EQFSWRGALLILGGFVLNLCVCGALMRPIT------------------------------------------------------------LKEDHTTPE--QNHVCRTQKE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DIKRVSPYSSLTKEWAQTCLCCCLQQEYSFLLM-SDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHQQ-AAFLMSILGVIDIIGNITFG-WLTDRRCLKNYQYVCYL-----FAVGMDGLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVT--LIPVVTTEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLV--DTTGSYTAAFLLCGFSMIFSSVLLGFARLIKRMR-----------KTQLQFIAKESDPKLQLWTNGSVAYS---------------------------VARELDQKHGEPVATAVPGYSLT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q503M4-1", "uniprot_id": "MT12B_DANRE", "id": "Q503M4-1", "name": "Monocarboxylate transporter 12-B", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQEKKKGGVL-----------------------PPDGGWG-WMIVAGCFVVTVCTRAVTRCISIFFVEFQMHFAKDYS-----GTAWIHSLVDCTTMLCAPLGSLIGNQLSCRIAVILGGFLASVGLVLSSFATSLEYLYATLGLLTGLG---FALCYTPAIAMVGIYFCERKALAYGIAMSGSGIGTFILAPVVQLLI-------EHYSWRGALLILGGFVLNLCVCGALLRPII------------------------------------------------------------LKEEEACPLPVDSECGYSVKP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTLNGGPTRSAASDAKQR--CFQSMQEYHFLLM-PDFLVLAGSFLLLASGCSLPFVYLVPYALDVGVGHQH-AAFLMSILGVIDIVGNITFG-WLTDRRCLKKYRNICYM-----FAVGMEGLCCLFIPLLRTFVWLVPFSVLYGYFDGAYVA--LIPVVTSDVVGRQYLSSALGVVYFLHAVPYLVSPPIGGWLV--DTTGTYTATFFLSGFALISSSLLLFSVAIIRYCQ-----------RNQKKNSLS-KIPKLVSCEGKQVDYY---------------------------PPKNKDLMLIIPATS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5NC32-1", "uniprot_id": "MOT11_MOUSE", "id": "Q5NC32-1", "name": "Monocarboxylate transporter 11", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTPKPAGPPDGGWG-WVVAAAAFAVNGLSYGLLRSLGLALPDLAEHFERSAQ-----DTAWVSALALAVQQAASPVGSALSTRWGARPVVMVGGVLTSLGLVFSAFARSLLHLYLGLGLLAGSG---WALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQFLL-------DTFGWRGALLLLGAVTLHLTPCGALLRPLALSG---------------------------------------------------------------DPLAPPRTPLAALG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LGLFKR-RAFSVFALGTALIGGGYFVPYVHLGPHALDQGMGGYG-AALVVAVAAVGDACARLASG-WLADQGWVPLPRLLVVFGSLTGLGVLAMGLVPTVGTEEGWGAPLLAAAGAYGLSAGSYAP--LVFGVLPGLVGIGGVVQATGLVMMLMSLGGLLGPPLSGFLR--DKTGDFSASFLVCSSFILSGSFIYMGLPRALPSCR---------PASPPATPPPERGELLPVPQVSLLSA------------------------------------GGTGSIRDTTC------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCK7-1", "uniprot_id": "MOT11_HUMAN", "id": "Q8NCK7-1", "name": "Monocarboxylate transporter 11", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTPQPAGPPDGGWG-WVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQ-----DTAWISALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFG---WALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLL-------DTFGWRGALLLLGAITLHLTPCGALLLPLVLPG---------------------------------------------------------------DPPAPPRSPLAALG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSLFTR-RAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYG-AALVVAVAAMGDAGARLVCG-WLADQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAP--LVFGVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLR--DETGDFTASFLLSGSLILSGSFIYIGLPRALPSCG---------PASPPATPPPETGELLPAPQAVLLSP------------------------------------GGPGSTLDTTC------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O70324-1", "uniprot_id": "MOT8_MOUSE", "id": "O70324-1", "name": "Monocarboxylate transporter 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALPSPASEEAEGPCQEANQEYQEPVCSPVPEPEPEPEPEPEPDPEPVPVPPPEPQPEPEPQPLPDPAPLPELGFEAEPVQEPEPTPTVETRGTARGFQPPEGGFG-WIVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNR-QVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATTGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCG---CSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIKMLG-------DKIKLAQTFQVLSTFMFVLTLLSLTYRPLLPSS-------------------------------------------------------QDTPSKRG-AHTLRQRFLVQFRK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YFNMRVFRQ-RTYRIWAFGIAAAALGYFVPYVHLMKYVEDKFKEIKE-TWVLLVCIGATSGLGRLVSGHISDSIPGLKKIYLQVLS-------FLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFIT--IMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLR--NCFGDYHVAFYFAGVPPIIGAVILFFVPLMHQRM------------FKKEQRDSSKDKMLSHDPDPNGE--------------------------------LLPGSP----TPEEPI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3U9N9-1", "uniprot_id": "MOT10_MOUSE", "id": "Q3U9N9-1", "name": "Monocarboxylate transporter 10", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVPSQE-----EPAAERETNEAQPPGPAP-SDDAPLPGPGPSDVSDVAAEKV-EVELTRSAGSEPPV----PPEGGWG-WLVMLAAMWCNGSVFGIQNAYGVLFVSMLDTFKAKDDDNMAFKTAWVGSLSMGMIFFCCPIVSVFTDMFGCRRTAVVGAAVGFIGLMSSSFVSSIEPLYLTYGIIFACG---CSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLGNLI-------SSVKLFNTLRILCIFMFVLFLAGFTYRPLVPST-------------------------------------------------------KEKESGGSRSSFFSRRKLSPPKK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VFNFALFKE-TTYAVWAAGIPLALFGYFVPYVHLMNHVKERFQDVNN-KEVLFMCIGITSGVGRLLFGRIADYLPGVKKVYLQVLS-------FFFIGLMSMMIPLCSAFGALIAVCLAMGLFDGCFIS--IMAPIAFELVGPQDASQAIGFLLGFMSIPMTVGPPIAGLLH--DKLGTYDVAFYLAGIPPFVGGVVLCLIPWIHSKK------------QRKISKNAGGEKMEKMLENQSS---------------------------------LLSGSSGIFKKDSASII-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VWK0-1", "uniprot_id": "Q9VWK0_DROME", "id": "Q9VWK0-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKKVYQDTTRPLPRVSRARYYN---------------KHDKSDLGDDFVAPDAGWA-WIVCVAAGVSNLSIYPCLQQFGFLFRERLSDLGMSSS-----QITAIINANPAVSACTGLLNGPMFRRFTFRQVAMAGSLLISGSLILTAFCETFLSYMVAYALLFGFG---MGISVSASSLAINTYFQKKRRRAAGFSWTITGLGPIFLPHLVTFLL-------TIYGVQGTTLLFAAISLHSFVCALIYQPVRYHVKPPVEQ--------------------------------------------------LADQEQQAEALCAHCSWQQKREPGGIFSSQYLC----------------------------------------------------------------------------------------QDDDAQRPGYEICEPGTPMLSRANDGWYGSRLSLTSGRLRFRTISSSKDLEQTQRLHCPISEEQNHESDEFLRPNNFRRERVESNLEAKLCCQCSAKREEHNNNRKEKEAEAEEAGMESAPLHDPQMSFLAKVVTFFDLDLLRD-FTFVNLVAGLTIINFGELNFSILTP-FILVDFGFDTPQITLAMSLLAGLDITMRFMVP-FLTEKIPWDNRVFFLIG-------VVGIALGRTVVACTRSYSLILCSFVWIGLCKGVRTI--FWPLIIPGYVPLNRLPGASGLQLLISGLFTLIGGPFVGLVR--DRYD-YSVTLHCLNMMSFVAATSWSLEALIRRHR-----------RKQRLVNS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWJ0-1", "uniprot_id": "Q9VWJ0_DROME", "id": "Q9VWJ0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDNGNNHNNNNNNNNDEALRLRLPEEQAEQLLPKNGSAGQTKIAPPTHTHSIAAASVPQKVPAKKKRDKSDLGEDFVAPDGGWG-WLVSVASGVNILVTFALAQQFGILFRDRMAGLGISSS-----ELTTIINTQIAVSAFTGLLNGPLFRRYTYRVVALVGSVLTFLGLFWMVFADTFAVYIMSFSILYGFG---RGLTVSASSLAVNTYFKVKRRTATAFQFGVAGLGPIVCPYFATYML-------YEFGVQGTTLLFAGASLHTIACSLIYQPVKWHVVK---------------------------------------------------------RDRDAEALQQVQPLAERED---------------------------------------------------------------------------------------------------QDEDIIKN---VVEPETPVLPRANDGWFGSRASLNSVGTRNRLNTWEK---SDSNGHVELKRLSSKDSN---PGRQLRSISVSHSIKEEEATGYNSDHEVQHTELTEKEKQELED--EKERQRRKKLPFYMKVVIFFDMDLLRD-ITYVNLAVGITLINFVEINFAILTP-FILSDLGFNKDQIALAMSTLGFFDLVVRFLIP-LITAKINLSNRTFFVVG-------ILGMCIGRMFLSMTSNFYVMMAIFLWLGLNKAFRTV--FWSLIIPSYVPLKRLPAAAGLQLLMSGTFSMIFGPLIGLIR--DHTS-YAVTLNLLNALCVMAFAGWYLEDFIRARS-----------RKSPPVKSIN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWJ1-1", "uniprot_id": "Q9VWJ1_DROME", "id": "Q9VWJ1-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASKQPRKVAPDGGWG-WVACFGVSLVNLATRSIEPSFGLLFGDTLKELNVGTT-----GAAVIISALDVCMNFSGLFVGPLLKEFSYRKVAIAGSLLCGLGLALTSPATSMAHILSTYSVINGIG---VGLSTSAAFVALNHYFKHKRGQAVGLSMAGTAMGMLIMPQLVRILL-------EAYDFRGAVLLLAGVALNATVGSVLLQPVKWHMKEEFDDEELMCISALPTPQPQLTVGGAGGAASAGAPVFKVIKEDGNEEDALPEMNTLLFHKPHPHQHSMRKNYSEMAMNTMNGSRLGIP----------------------------------------------------------------------------------------KRPTFPRIMSLAGVQSAAHGAGGDSGGYTSQAEVNATQLRCRKASVTSNL-SYMDFTGSILQVHLNTGDDEFEQNDRELRRVGTATGSIVLGGHRDSFIKMKPTELDKQAEAAAALDEEAKKKAKKPGFWRRFADLLDIDMLKD-KMFLNLLFGLSIFYVAEMNFKMVTP-FFFANLGYQKTDVAFCLSITAITDIAARIVLP-PIFDRTTIKKRTIFLVS-------IIFVALTRSIMAEQTEWTQLMIWLSICGFFRGSALS--NFTLTVSEYCSLEKLPSAFGWHLVGKALFVITFGPLIGLIR--DVTDSYPICIHTQSVCIMICATAWGIEYLVEYIQ-----------SRRRTADAAQLPTQDVGATTTATSDQNDVKL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E960-1", "uniprot_id": "Q0E960_DROME", "id": "Q0E960-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDVQSSRVVPDGGYG-WIVVAAVALINMTNQSILSVFGQLFVGELQKMQEDTF-----TAALITNLNSLALNFSGLFIGPAIKSFKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFG---LGLISPSTFMAINSYFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLL-------DNHGFRYAVLSMSSLSLFGLFGAAFLKPLN-----------------------------------------------------------------PPAKHNNRK--------------------------------------------------------------------------------------------------------------HIRLLTEADGEK----------------------------------------TSPLQVVIVPTNQSKIERSPPNVDTLCSRMG-------------------------------------------QRLVQAMDLELLKD-LVFWSIIVGMALVYTATINFTMIFPGFLGQTAQLNSQMVAFCMSLVAGADIVFRLLLP-IVTDHLRIPYRVVFLIG-------IVGLFVARCVLAENQTLPVIITMSVLTGMMKSATVI--NNNLTISAHCRSEKLAGGLGLSMMSKGVIVITVGQLLGWVR--DYADSYLICLYAQGVILLVVVLVWTPEILYRHR-------------RQRCATNKSMETQSIDAAEVAKLNS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQU7-1", "uniprot_id": "Q9VQU7_DROME", "id": "Q9VQU7-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "MVIQCTCDCNCSDSRDNRSVISCLLPGRSQPYKLGSSFGGDDMEQRIPYYRRLSNTSSALYGSCPQLLPSSSSTNNRHSWLRIPKNPQENPSENPSENPRQYSSLVRPKQRSPVLCNKCALXRRYNLSCEHPKQTAGHPGSGNTDQTAQTKPDKDSTNQRYLCYECRFNNQPLAWWVSCPRLSYLPAEQTKMQSTTTPTRHCHGGVGTQTTLPQTTSTPPTLPRFPSKRHCDNFGSYATLPTIEHQMTMPMMPHCSRHGGGGGGGVVGVGGLGGAVGSGMPSVMPAPPPPRYANPNINGCCYMYNPMPPAHQSHHQHDHHHAQQHHPVAQHQHHPHQYGPQYCLCDNWYHQPPPTQQQQHHHQQRAKNLMANGGCYFGYEANHHPSLHATTPHPSHITDEEDSAFPGLADREFHLLHRNIPALRRTGVDTTRIRQYFYPDGGWG-WIICGVSFLVHILTTGLQLSYGLLWFYAVQYLHNTSG------IELLGALSWSVSMVATSFVVSLCRKRSIRLLSIVGGLVMPLGILFTSFATEFGQVVFSYGIVFGVG---VAMVREASTVMLGNYFKRRRQFVEMVAMSGEGVGIALFSVILKEGV-------GKAGWRLGLQIVAALTALSFFMGLMYRPASLYHP---------------------------------------------------------QRRAIQHLKNQRKKMREKKP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILSQDVESTPKYFFLDISSLKS-VTVKILLMTSSVASFGIYTPMFLMALNAAEQGS-DVQELVLLQTFLGISMALGVVIAGALLRRCFVIRHFVINTKIVT--QLFLSIVALAILFLSFVMGYTGLCILSWLYGIGLGGFQY--SLKILALERIKLKHFSKAWGFIRGVESVPVLISVPLTSFLN--DYSLKYGRAGYYICSAAAAISGIIIFFISEPQQQHQQQQQQLHHHYQQRNGHLATPTLMRHASARQHRPHLPMDYGYGEYPAPDLLSRSCISLNQMEPYLQANFCQRHMLQQQQQQQQQQQHSHLQQLACHNLDLQPHQGREAYQLGQGSIGAKMGKRLQRSLSFIQQHSNCCDGQMYCSWHSTYELGCHKSNKNPGSADRQPLICTCSSPNRNPVTYGTHGPTGPPGPTGPPGPPSSTRSRSVPEGLSTMSQQCNCRQGPATFAAPTREFIYVPHAYASLQRTPHRHSQGAGSGPGPGNSALRNNPQCRLKRSQSLCRPNAVQFVEQITTSV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4LFF4-1", "uniprot_id": "A0A0B4LFF4_DROME", "id": "A0A0B4LFF4-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------MSRNRRRSFPSSQYEDKTAAAQPSGSSLRSQSLSRLDISVQNSSIYYNDTRNTRPQMVSVAVGTVSTDILNGRTSFLSLSQSHGSEVDLPSFYESFNPTFLPKLPIRRFPHMLVGASNEPEISKNQPAIPPSRPIEPISEVPFVEPAFEKKYSRTRGFSKELSTHRDNENEYIESTDEVSQMLSFTSYTDEYDRAEPLITKTQKFYKKRSPLIPKYDSEDSYVVPKETDQQESGLSFNVTTVQLADTASPESFSEYDGNRTRKQSFDMESKNSKESFDFSRGGRRLGSGMVFIYMVIPPDGGFG-WVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSIS-----SVSFVASVQIGCYFTSGAFSAVLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGITLSMIWASSQLIVGYYFERYRPMANGFSCSGGGAGIVLFTFLNSWLV-------PIIGWRNMLRTQAGLIMLILLMVVAYVEVAPTQVGMYHLPGSSDTSSDEYYG---------------------------------NFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCPSCSN------------------------------------------------------------------------------------------------------------CCWRRRKKSQNADEQNLLIRPAPLEREDLFYTGPAEYEKPHSKENVDGKEFLLMGSDKNTQQVNYGIKNIRVDDEPDRISRVHRERRWSNENQKKQNSCRNSRFMLTVLKLFDYRLLKQ-FEFKILVASAFLFPMGFNIPFVYSS----ARTTIPVEYARMIGPIIGISNLVMRNILG-ILAYKRRSWTLGLCGCG-------LIFGGVSVLISAFYGENLIWFQFLYGFSYAVAPAVYSTLRGLIYVKYLGLSKLTNAFGITSLAMGMGAFIGTTIAGKLI--GITGNYSAAFCFAGLCLIVSGFLKLLLPLLIKCR-------------NRMAQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08777-1", "uniprot_id": "MCH5_YEAST", "id": "Q08777-1", "name": "Riboflavin transporter MCH5", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSDSLTPKDTIVPEEQTNQLRQPDLDEDSIHYDPEADDLESLETTASYASTSVSAKVYTKKEVNKGTDIESQPHWGENTSSTHDSDKEEDSNEEIESFPEGGFKAWVVTFGCFLGLIACFGLLNSTGVIESHLQDNQLSSES---VSTIGWLFSLFLFVCSASCIISGTYFDRNGFRTIMIVGTVFHVAGLFATANSTKYWHFILSFAIVCGFG---NGIVLSPLVSVPAHYFFKRRGTALAMATIGGSVGGVVFPIMLRSFFSMKSDTDPTYGFVWGIRTLGFLDLALLTLSIILVKERLPH-------------------------------------------------------------VIENSKDGESRWRYILR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYILQCFDAKAFLD-MKYLFCVLGTVFSELSINSALTYYGSYATSHGISAND-AYTLIMIINVCGIPGRWVPGYLSDKFGRFNVAIATLLT--------LFIVMFVGWLPFGTNLTNMYVISALYGFCSGSVFS--LLPVCCGQISKTEEFGKRYSTMYFVVGFGTLVGIPITGAIISIKTTADYQHYIIFCGLATFVSAVCYIISRAYCVG--------------FKWVRF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : * . . : . .. * : . ** . . . . . . : ", "identical_positions": 4, "similar_positions": 18, "identity": "0.27%" }, { "cls_id": "homologset.agr.SGD:S000005834", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C6B1-1", "uniprot_id": "S35E1_RAT", "id": "P0C6B1-1", "name": "Solute carrier family 35 member E1", "aln": "----------------MAAAAAAGPGAGAGIPG-----------------ASGG-GGAREG------------------ARVAALCLLWYALS------AGGNVVNKVILSAFPFPVTVSLCHILA---LCAGLPPLLRAWRVPPAPPVSGPGPSP-----------------HPASGPLLPPRFYPRYVLPLAFGKYFASVSAHVSIWKVPVSYAHTVKATMPIWVVLLSRIIMKEKQSTKVYLSLVPIISGVLLATVTELS----------FDVWGLVSALAATLCFSLQNIFSKKVLRDS-----------------------------RIHHLRLLNILGCHAVFFMIPTWVLVDLSTFLVSSDLAYVSQWPWTLLLLVVSGFCNFAQNVIAFSILNLISPLSYSVANATKRIMVIAVSLIMLRNPVTSTNVLGMMTAILGVFLYNKTKYDANQQARRHLLPVSTSDLSNREHLRSPMEKPHNGALFPQQGDFQY-RNILLTDHFQYSRQGHPNSYALSRHDV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CD26-1", "uniprot_id": "S35E1_MOUSE", "id": "Q8CD26-1", "name": "Solute carrier family 35 member E1", "aln": "----------------MAAAATAGPGAGAGVPG-----------------AGGG-GGAREG------------------ARVAVLCLLWYALS------AGGNVVNKVILSAFPFPVTVSLCHILA---LCAGLPPLLRAWRVPPAPPVSGPGPGP-----------------HPASGPLLPPRFYPRYVLPLAFGKYFASVSAHVSIWKVPVSYAHTVKATMPIWVVLLSRIIMKEKQSTKVYLSLVPIISGVLLATVTELS----------FDVWGLVSALAATLCFSLQNIFSKKVLRDS-----------------------------RIHHLRLLNILGCHAVFFMIPTWVLVDLSTFLVSSDLAYVSQWPWTLLLLAVSGFCNFAQNVIAFSILNLISPLSYSVANATKRIMVITVSLIMLRNPVTSTNVLGMMTAILGVFLYNKTKYDANQQARRHLLPISTSDLSSREHLRSPVEKPHNGALFPQQGDFQY-RNILLTDHFQYSRQGHPNSYALSRHDV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96K37-1", "uniprot_id": "S35E1_HUMAN", "id": "Q96K37-1", "name": "Solute carrier family 35 member E1", "aln": "-----------------MAAAAVGAGHGAGGPG-----------------AASSSGGAREG------------------ARVAALCLLWYALS------AGGNVVNKVILSAFPFPVTVSLCHILA---LCAGLPPLLRAWRVPPAPPVSGPGPSP-----------------HPSSGPLLPPRFYPRYVLPLAFGKYFASVSAHVSIWKVPVSYAHTVKATMPIWVVLLSRIIMKEKQSTKVYLSLIPIISGVLLATVTELS----------FDMWGLVSALAATLCFSLQNIFSKKVLRDS-----------------------------RIHHLRLLNILGCHAVFFMIPTWVLVDLSAFLVSSDLTYVYQWPWTLLLLAVSGFCNFAQNVIAFSILNLVSPLSYSVANATKRIMVITVSLIMLRNPVTSTNVLGMMTAILGVFLYNKTKYDANQQARKHLLPVTTADLSSKERHRSPLEKPHNGLLFPQHGDYQYGRNNILTDHFQYSRQSYPNSYSLNRYDV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VR50-1", "uniprot_id": "S35E1_DROME", "id": "Q9VR50-1", "name": "Solute carrier family 35 member E1 homolog", "aln": "--------------------------------------------------MLGKRTGSRHI------------------AVVLLMCLFWYVIS------SSNNVIGKMVLNEFPFPMTVTLVQLCS---ITLYSGPFFNLWRIRKYQDIPRP--------------------------------YYYRLIVPLALGKLLASVTSHISLWKVPVSYAHTVKATMPLFTVVLTRVFFGEKQPTLVYLSLLPIITGVGIATVTEIS----------FDMMGLISALISTMGFSMQNIFSKKVLKDT-----------------------------NIHHLRLLHLLGKLSLFIFLPLWLYMDSFAVFRHTAIKNLDYR--VIALLFADGVLNWLQNIIAFSVLSLVTPLTYAVASASKRIFVIAVSLLILGNPVTWVNCVGMTLAIVGVLCYNRAKQLTRGRE-QPTLPLSQTSYVKYSPLEQQADPYYRGSVN---GKLSNGLHRTPGNSLLANGSGMPSGTATRLLFV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0ABK0L9N7-1", "uniprot_id": "A0ABK0L9N7_RAT", "id": "A0ABK0L9N7-1", "name": "", "aln": "----------MSSAAKSQVLEETAPGCEEEPKGKTLFTWGSLFGHRSEKIVFTKGDGSPEE------------------SLLTVTITETTVIESDLGVWSSRALIYLTLWFFFSFCTLFLNKYILS---LLEGEPSMLGAVQMLSTTLIGCVKIFVPCCL-------------YQHKTRLSYPPNFIMTMLFVGLMRFATVVLGLVSLKNVAVSFAETVKSSAPIFTVIMSRMILGEYTGLLVNLSLIPVMGGLALCTATEIS----------FNILGFSAALSTNIMDCLQNVFSKKLLSGDK---------------------------YRFSAPELQFYTSAAAVALLIPAWTFFMDVPVIGGSGKS-FSYSQDIVLLLLTDGALFHLQSVTAYALMGKISPVTFSVASTVKHALSIWLSIIVFGNKITSLSAIGTILVTVGVLLYNKARQYQQETMQSLVTATSQGPNDDTEPLVSQDSRQHH----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22215-1", "uniprot_id": "SLY41_YEAST", "id": "P22215-1", "name": "Uncharacterized transporter SLY41", "aln": "MIQTQSTAIKRRNSVHKNLFDPSLYQIPEPPRGGFQHQKKEYSKETFSNQVFGYDITSLKKRFTQLFPSNIQGYLPEVDLRITIICSIWYVTS------SISSNLSKAILRTFNHPIALTELQFLVSAVLCVGFASIVNLFRLPRLKHTKFSKALNSFPDGILPEYLDGNFRSSILHKFLVPSKLVLMTTFPMGIFQFIGHITSHKAVSMIPVSLVHSVKALSPIITVGYYKFFEHRYYNSMTYYTLLLLIFGVMTTCWSTHGSKRASDNKSGSSLIGLLFAFISMIIFVAQNIFAKNILTIRRKVGILPSSSTDDVTSKEGQPSLDKTRFSPLQVDKITILFYCSCIGFSLTLLPFLTGELMHGGSVIN--DLTLETVALVAIHGIAHFFQAMLAFQLIGLLSSINYSVANIMKRIVVISVALFWET-KLNFFQVFGVILTIAGLYGYDKWGLSKKDGRQA-----------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . . : : : * . . : : .:. :: . :.: : : . :: :.** ..:**: *: .* :.: . . :*: :: *: : . .: *: *: : : **:*:*::* : .: .: : :. . . : : *: * * : *: ::. ::.:.::**. *: . * :::: :. . .* . *: *:: . ", "identical_positions": 27, "similar_positions": 97, "identity": "5.12%" }, { "cls_id": "homologset.agr.SGD:S000005835", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIW8-1", "uniprot_id": "SNUT1_RAT", "id": "Q5XIW8-1", "name": "U4/U6.U5 tri-snRNP-associated protein 1", "aln": "MGSSKKHRGEKEAAGTTAAAGTGGTTEQPPRHREHKKHKHRSSGGGSSGGERRKRSRERGAERGSGRRGAEAEARSGAHGRERSQAEPSERRVKREKRDEGYEAAASSKASSGDASSLSIEETNKLRAKLGLKPLEVNAVKKEAGTKEEPVAADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFEQRRQDLYSARDLQGLTVEHAIDSFREGETVVLTLKDKGVLQEGE--DVLVNVNMVDKERADKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILAKYDEELEGERPHSFRLEQGGMADGLRERELEEIRTKLRLQAQSLNTVGPRLASEYLSPEEMVTFKKTKRRVKKIRKKEKEVIMRADDLLPLGEDQTQDGDFGSRLRGRGRRRVPEVEEEALEDEEKDPVAQPPPSDDTRVENMDISDEEDGGALPSGPPE-LEEDEAELELQKQLEKGRRLRQLQQLQQLRDSGEKVLEIVKKLESRQRGWEEEEDPERKGTIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEEKQHQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQKTPYIVLSGSGKSMNANTITK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z315-1", "uniprot_id": "SNUT1_MOUSE", "id": "Q9Z315-1", "name": "U4/U6.U5 tri-snRNP-associated protein 1", "aln": "MGSSKKHRGEKEAAGTTAAAGTGGTTEQPPRHREHKKHKHRSSGGGSSGGERRKRSRERGSERGSGRRGAEAEARSGAHGRERSQAEPSERRVKREKRDDGYEAAASSKASSGDASSLSIEETNKLRAKLGLKPLEVNAVKKEAGTKEEPVAADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFEQRRQDLYSARDLQGLTVEHAIDSFREGETVVLTLKDKGVLQDGE--DVLVNVNMVDKERADKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILAKYDEELEGERPHSFRLEQGGMADGLRERELEEIRTKLRLQAQSLSSVGPRLASEYLSPEEMVTFKKTKRRVKKIRKKEKEVIMRADDLLPLG-DQTQDGDFGSRLRGRGRRRVPEVEEEALEDEEKDPVAQPPPSDDTRVENMDISDEEDGGALPPGSPEGLEEDEAELELQKQLEKGRRLRQLQQLQQLRDSGEKVLEIVKKLESRQRGWEEEEDPERKGTIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEEKQHQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQKTPYIVLSGSGKSMNANTITK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43290-1", "uniprot_id": "SNUT1_HUMAN", "id": "O43290-1", "name": "U4/U6.U5 tri-snRNP-associated protein 1", "aln": "MGSSKKHRGEKEAAGTTAAAGTGGATEQPPRHREHKKHKHRSGGSGGSGGERRKRSRERGGERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEE--DVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLG-DQTQDGDFGSRLRGRGRRRVSEVEEE------KEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQKTPYIVLSGSGKSMNANTITK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12420-1", "uniprot_id": "SNU66_YEAST", "id": "Q12420-1", "name": "66 kDa U4/U6.U5 small nuclear ribonucleoprotein component", "aln": "----------------------------------------------------------------------------MNKTENLSIEETNEIREKLGMKP----IPVFQEKNTDHKESLSIEETNELRASLGLKLIPP----------QQNFNSSPPNVHNTSKIDELREKITKFQKK--ANAPLRMAHLLEETN--VNDDSSWLENMDAIPSSHESKRS--------------STLPRKGATKEDE----NIDLHNVQVSYNIEALSPKKDTILTLKESSIFDDTDSTEVLENVKAAEENADREKLRLRQMNKDRRQKKKILNVSSLDIEE-----EEEGEKHSITTTHLIIGAEQGVMKAPNTISAKPPTGKVKVNFDSANNMSDEDGGDFKP----LKIKKRKIKDPRSTKARKSKITDKMEIVKLVDEDES---------------LSWMEEE-------QPVTIINPRTSSNNE-----------------LKGPEDLAREIEKARDEEK-RRTESILKMREISNS-IVVDEKVTFLNTLDTSLSERSATENK----VKVHGEGEKNIGDVTN-GHTKEGSGNNTLTEAVNNE--PNYEGDAENAPNFFSGLASTLGYLRKKSVFTTGDVDLKPGKDVNNS--------------------ESLRRDVRNKEHTGTGTYTKDKLHGLEQFTSSDSSNANTHSKRQ-DHYDPDIKLVYRDEKGNRLTTKEAYKKLSQKFHGTKSNKKKRAKMKSRIEARKNTPEN-------GSLFEFDDN-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: * *..* * * : .. .: .:.. .********:***.**** : :: . :. * : :*****:: ::* * * : * * : ::* ::*:*. : ..:: .. *** .: :. : **:.: *.: *::: : :****:..:::: : :** **: .::: :::.**: : * : .*..* :: : .*: . .* : : * .. . . : *:::: :* ..:. . ..:: . :.:** * : : * .*. : ::: * :: . :. :*** :**. * .:. * : *: *:* :: ** ** ..: ::::: :* * * *. *:: : . .* . .*.* .:. .* :.:*::.. * : : . :: * : .:* . *. .:. : :. : .*. :::. *::... : : : * : * .. **. ..: :**: :::: :. .. *:. :: * *.**:*: * **.*.:**.***:::**::***. *.* * : .::: . : *:: :::: ", "identical_positions": 125, "similar_positions": 247, "identity": "15.45%" }, { "cls_id": "homologset.agr.SGD:S000005837", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZ86-1", "uniprot_id": "NOP58_RAT", "id": "Q9QZ86-1", "name": "Nucleolar protein 58", "aln": "-MLVLFETSVGYAIFKVLNEKKLQEVDSLWKEFETPEKANKIVKLKHFEKFQDTAEALAAFTALMEGKINKQLKKVLKK-IVKEAHEPLAVADAKLGGVIKEK-LNLSCIHSPVVNELMRGIRSQMDGLIPGVEPREMAAMCLGLAHSLSRYRLKFSADKVDTMIVQAISLLDDLDKELNNYIMRCREWYGWHFPELGKIISDNLTYCKCLQKVGDRKNYASATLSEFLSEEVEAEVKAAAEISMGTEVSEEDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGELVGARLIAHAGSLLNLAKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQTSPKHKGKISRMLAAKTVLAIRYDAFGED--SSSAMGAENRAKLEARLRILEDRGIRKISGTGKALAKAEKYEHKSEVKTYDPSGDSTLPTCSKKRKIEEVDKEDEITEKKAKKAKIKIKAEVEEEM--EEAEEEQVVEEEPTVKKKKKKDKKKHIKEEPLSEEEPCTSTAVPSPEKKKKKKKKKDAED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DFW4-1", "uniprot_id": "NOP58_MOUSE", "id": "Q6DFW4-1", "name": "Nucleolar protein 58", "aln": "-MLVLFETSVGYAIFKVLNEKKLQEVDSLWKEFETPEKANKIVKLKHFEKFQDTAEALAAFTALMEGKINKQLKKVLKK-IVKEAHEPLAVADAKLGGVIKEK-LNLSCIHSPVVNELMRGIRSQMDGLIPGVEPREMAAMCLGLAHSLSRYRLKFSADKVDTMIVQAISLLDDLDKELNNYIMRCREWYGWHFPELGKIISDNLTYCKCLQKVGDRKNYASASLSEFLSEEVEAEVKAAAEISMGTEVSEEDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGELVGARLIAHAGSLLNLAKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQSSPKHKGKISRMLAAKTVLAIRYDAFGED--SSSAMGIENRAKLEARLRILEDRGIRKISGTGKALAKAEKYEHKSEVKTYDPSGDSTLPTCSKKRKIEEVDKEDEITEKKAKKAKIKIKAEVEEEMEEEEAEEEQVVEEEPTVKKKKKKDKKKHIKEEPLSEEEPCTSTAVPSPEKKKKKKKKKDAED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2X3-1", "uniprot_id": "NOP58_HUMAN", "id": "Q9Y2X3-1", "name": "Nucleolar protein 58", "aln": "-MLVLFETSVGYAIFKVLNEKKLQEVDSLWKEFETPEKANKIVKLKHFEKFQDTAEALAAFTALMEGKINKQLKKVLKK-IVKEAHEPLAVADAKLGGVIKEK-LNLSCIHSPVVNELMRGIRSQMDGLIPGVEPREMAAMCLGLAHSLSRYRLKFSADKVDTMIVQAISLLDDLDKELNNYIMRCREWYGWHFPELGKIISDNLTYCKCLQKVGDRKNYASAKLSELLPEEVEAEVKAAAEISMGTEVSEEDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGELVGARLIAHAGSLLNLAKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQTSPKHKGKISRMLAAKTVLAIRYDAFGED--SSSAMGVENRAKLEARLRTLEDRGIRKISGTGKALAKTEKYEHKSEVKTYDPSGDSTLPTCSKKRKIEQVDKEDEITEKKAKKAKIKVKVE-------EEEEEKVAEEEETSVKKKKKRGKKKHIKEEPLSEEEPCTSTAIASPEKKKKKKKKRENED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VM69-1", "uniprot_id": "Q9VM69_DROME", "id": "Q9VM69-1", "name": "Nucleolar protein 58", "aln": "-MFVLYETPAGYAIFKLLDEKKLEQVDNLYQEFETPEKANKLLKLKHFEKFNDTTEALAAATAAVEGKVAKPLKKTLKKLLVDDVQSSLLVADAKLGTAIKDK-LSVQCVCNTGVQELMRCIRQQADSLLGGLPKREMTAMALGLAHSLSRYKLKFSPDKIDTMIVQAQCLLDDLDKELNNYMMRAREWYGWHFPELGKIITDNIAFVKTIKLVGTRDNMATSDLSDILPEDVEEKVKEAAEISMGTEISEEDVLNIQCLCDEIISINDYRTHLYDYLKARMMAMAPNLTVLVGDTVGARLIAHAGSLINLAKHPSSTVQILGAEKALFRALKTKKDTPKYGLIYHAQLVGQASQKNKGKMSRSLAAKASLATRVDAFGEE--ATFELGAAHKVKLESRLRLLEEGNLRKLSGTGKAKAKFEKYQAKSEVFTYQPEADNTLN-VKKKRKHSESEQQTPVKKE-------------------EPAEEEAEVKSE---KKKKKKKKQKDEEVEAVEEAAAPEPEDQPTPAKKKKKSKHQE---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12499-1", "uniprot_id": "NOP58_YEAST", "id": "Q12499-1", "name": "Nucleolar protein 58", "aln": "MAYVLTETSAGYALLKASD-KKIYKSSSLIQDLDSSDKVLKEFKIAAFSKFNSAANALEEANSIIEGKVSSQLEKLLEE-IKKDKKSTLIVSETKLANAINKLGLNFNVVSDAVTLDIYRAIKEYLPELLPGMSDNDLSKMSLGLAHSIGRHKLKFSADKVDVMIIQAIALLDDLDKELNTYAMRCKEWYGWHFPELAKIVTDSVAYARIILTMGIRSKASETDLSEILPEEIEERVKTAAEVSMGTEITQTDLDNINALAEQIVEFAAYREQLSNYLSARMKAIAPNLTQLVGELVGARLIAHSGSLISLAKSPASTIQILGAEKALFRALKTKHDTPKYGLLYHASLVGQATGKNKGKIARVLAAKAAVSLRYDALAEDRDDSGDIGLESRAKVENRLSQLEGRDLRTTPKVVREAKKVEMTEAR----AYNADAD-----TAKAASDSESDSDDEEEEKK------------------EKKEKKRKRDDDEDSKDSKKAKKEKKDKKEKKEKKEKKEKKEKKEKKEKKSKKEKKEKK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** **..***::* : **: : ..* :::::.:*. * .*: *.**:.:::** .: :***: . *:* *:: : .: :..* *:::**. .*:. *... : .. . :: * *:. *: *: .::: *.******:.*::****.**:*.**:** .**********.* **.:**********.**::*.::: : : :* *.: : : **::*.*::* .** ***:*****::: *: ** *. :::.: ** :* :**. ** *:***:* :**: ********:***:.*** .:**:**************:::*******:***.****:: *:***::* ****: :: * **:.*: : :* :.*:* ** ** .:*. . . : * * : : :*:...* * . .: :.: :: * *:: ..: *..** *:*. : * .: :**.*.:::: ", "identical_positions": 196, "similar_positions": 181, "identity": "36.23%" }, { "cls_id": "homologset.agr.SGD:S000005839", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62718-1", "uniprot_id": "RL18A_RAT", "id": "P62718-1", "name": "Large ribosomal subunit protein eL20", "aln": "MKASGTLREYKVVGRCLPTPKCHTPPLYRMRIFAPNHVVAKSRFWYFVSQLKKMKKSSGEIVYCGQVFEKSPLRVKNFGIWLRYDSRSGTHNMYREYRDLTTAGAVTQCYRDMGARHRARAHSIQIMKVEEIA-AGKCRRPAVKQFHDSKIKFPLPHRVLRRQHKPRFTTKRPNTFF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62717-1", "uniprot_id": "RL18A_MOUSE", "id": "P62717-1", "name": "Large ribosomal subunit protein eL20", "aln": "MKASGTLREYKVVGRCLPTPKCHTPPLYRMRIFAPNHVVAKSRFWYFVSQLKKMKKSSGEIVYCGQVFEKSPLRVKNFGIWLRYDSRSGTHNMYREYRDLTTAGAVTQCYRDMGARHRARAHSIQIMKVEEIA-AGKCRRPAVKQFHDSKIKFPLPHRVLRRQHKPRFTTKRPNTFF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02543-1", "uniprot_id": "RL18A_HUMAN", "id": "Q02543-1", "name": "Large ribosomal subunit protein eL20", "aln": "MKASGTLREYKVVGRCLPTPKCHTPPLYRMRIFAPNHVVAKSRFWYFVSQLKKMKKSSGEIVYCGQVFEKSPLRVKNFGIWLRYDSRSGTHNMYREYRDLTTAGAVTQCYRDMGARHRARAHSIQIMKVEEIA-ASKCRRPAVKQFHDSKIKFPLPHRVLRRQHKPRFTTKRPNTFF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZWJ4-1", "uniprot_id": "RL18A_DANRE", "id": "Q7ZWJ4-1", "name": "Large ribosomal subunit protein eL20", "aln": "MKASGTLREYKVVGRLLPSVKNPAPPLYRMRIFAPNHVVAKSRFWYFVSQLRKMKKASGEIVYCGLVFEKSPLKVKNFGIWLRYDSRSGTHNMYREYRDLTTSGAVTQCYRDMGARHRARAHAIQIMKVQVIA-ANKCRRPAIKQFHDSKIKFPLPHRVLRRQHKPRFTTKRPNTFF-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41093-1", "uniprot_id": "RL18A_DROME", "id": "P41093-1", "name": "Large ribosomal subunit protein eL20", "aln": "MRAKGLLKEYEVVGRKLPSEKEPQTPLYKMRIFAPDNIVAKSRFWYFLRQLKKFKKTTGEIVSIKQVYETSPVKIKNFGIWLRYDSRSGTHNMYREYRDLTVGGAVTQCYRDMGARHRARAHSIQIIKVDSIP-AAKTRRVHVKQFHDSKIKFPLVQRVHHKGNRKLFSFRKPRTYFQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX24-1", "uniprot_id": "RL20B_YEAST", "id": "P0CX24-1", "name": "Large ribosomal subunit protein eL20B", "aln": "---MAHFKEYQVIGRRLPTESVPEPKLFRMRIFASNEVIAKSRYWYFLQKLHKVKKASGEIVSINQINEAHPTKVKNFGVWVRYDSRSGTHNMYKEIRDVSRVAAVETLYQDMAARHRARFRSIHILKVAEIEKTADVKRQYVKQFLTKDLKFPLPHRVQKS--TKTFSYKRPSTFY-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::**:*:** **: . . *::*****.:.::****:***: :*:*.**::**** : * * ::****:*:************:* **:: .** *:**.****** ::*:*:** * : . :* :*** ..:**** :** : *: ::* *:: ", "identical_positions": 79, "similar_positions": 51, "identity": "44.38%" }, { "cls_id": "homologset.agr.SGD:S000005843", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62720-1", "uniprot_id": "ZNT1_RAT", "id": "Q62720-1", "name": "Proton-coupled zinc antiporter SLC30A1", "aln": "---MGCWGRNRGRLLCMLLLTFMFMVLEVVVSRVTASLAMLSDSFHMLSDVLALVVALVAERFARRTHATQ------------------------------------KNTFGWIRAEVMGALVNAIFLTGLCFAILLEAVERFIEP---HEMQQPLVVLSVGVAGLLVNVLGLCLFHHHSGEGQGAGHGHSHG-HGHGH-LAKGAR--KAGRAG-GEAGAPPG-RAPDQEPDQEETNTLVANTSNSNGLKADQAEP--EKLRSDDPVDVQVNGNLIQESDSLESEDNRAGQLNMRGVFLHVLGDALGSVIVVVNALVFYFSWKGCTEDDFCVNPCFPDPCKSSVELMNS--TQAPMHEAGPCWVLYLDPTLCIIMVCILLYTTYPLLKESALILLQTVPKQIDIKHLVK-ELRDVEGVEEVHELHVWQLAGSRIIATAHIKCEDPAS----YMQVAKTIKDVFHNHGIHATTIQPEFAS-------------------------------------------------------VGSKSSVVPCELACRTQCALKQCCGTRPQVHSGKEAEKAPTVSISCLELSENLEKK-------PRRTKAEGSVPAVVIEIKNVPNKQPESSL----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60738-1", "uniprot_id": "ZNT1_MOUSE", "id": "Q60738-1", "name": "Proton-coupled zinc antiporter SLC30A1", "aln": "---MGCWGRNRGRLLCMLLLTFMFMVLEVVVSRVTASLAMLSDSFHMLSDVLALVVALVAERFARRTHATQ------------------------------------KNTFGWIRAEVMGALVNAIFLTGLCFAILLEAVERFIEP---HEMQQPLVVLSVGVAGLLVNVLGLCLFHHHSGEGQGAGHGHSHG-HGHGH-LAKGAR--KAGRAG-VEAGAPPG-RAPDQ----EETNTLVANTSNSNGLKADQAEP--EKLRSDDPVDVQVNGNLIQESDNLEAEDNRAGQLNMRGVFLHVLGDALGSVIVVVNALVFYFNWKGCTEDDFCTNPCFPDPCKSSVEIINS--TQAPMRDAGPCWVLYLDPTLCIIMVCILLYTTYPLLKESALILLQTVPKQIDIKHLVK-ELRDVDGVEEVHELHVWQLAGSRIIATAHIKCEDPAS----YMQVAKTIKDVFHNHGIHATTIQPEFAS-------------------------------------------------------VGSKSSVLPCELACRTQCALKQCCGTRPQVHSGKDAEKAPTVSISCLELSENLEKK-------ARRTKAEGSLPAVVIEIKNVPNKQPESSL----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6M5-1", "uniprot_id": "ZNT1_HUMAN", "id": "Q9Y6M5-1", "name": "Proton-coupled zinc antiporter SLC30A1", "aln": "---MGCWGRNRGRLLCMLALTFMFMVLEVVVSRVTSSLAMLSDSFHMLSDVLALVVALVAERFARRTHATQ------------------------------------KNTFGWIRAEVMGALVNAIFLTGLCFAILLEAIERFIEP---HEMQQPLVVLGVGVAGLLVNVLGLCLFHHHSGFSQDSGHGHSHGGHGHGHGLPKGPRV-KSTRPGSSDINVAPGEQGPDQ----EETNTLVANTSNSNGLKLDPADP--ENPRSGDTVEVQVNGNLVREPDHMELEEDRAGQLNMRGVFLHVLGDALGSVIVVVNALVFYFSWKGCSEGDFCVNPCFPDPCKAFVEIINS--THASVYEAGPCWVLYLDPTLCVVMVCILLYTTYPLLKESALILLQTVPKQIDIRNLIK-ELRNVEGVEEVHELHVWQLAGSRIIATAHIKCEDPTS----YMEVAKTIKDVFHNHGIHATTIQPEFAS-------------------------------------------------------VGSKSSVVPCELACRTQCALKQCCGTLPQAPSGKDAEKTPAVSISCLELSNNLEKK-------PRRTKAEN-IPAVVIEIKNMPNKQPESSL----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B789-1", "uniprot_id": "A0A8M2B789_DANRE", "id": "A0A8M2B789-1", "name": "", "aln": "---MACAP-NRVRLLCMLSLTFGFFIVEVVVSRITSSLAMLSDSFHMLSDVIALVVALVAVRFAEQTQSTN------------------------------------KNTFGWIRAEVMGALVNAVFLTALCFTIILEAIERFTEP---HEIEQPWVVIGVGALGLLVNLLGLCLFHGHAG---GGGHGHSHGGHGHSHGGAKKHKNGKVRRSETLEDSRSAG----------EETNNLVANHNSPNGVNAERKAAGKWDMCHSDSLDLQING--SAPYDELENGHDAASQLNMRGVFLHVLGDALGSVIVVINAIIFVFVWKPCEPGTICENPCSGQHCADHALNISSPLTNGTLIKAGPCWVLYLDPTLCIIMVCILLYTTYPLLKESALILLQTVPKQIDMHQLNA-RLRDLEGVLAVHELHIWQLAGSRIIATAHIKCHDPTS----YMDVAKRIKDFFHDEGIHATTIQPEFVT-------------------------------------------------------VNSESRASLCELSCRTQCAPKLCCG---AVDTAKPLEGSLESKKSCESKTPTLPSAS----VTSLEIISESVEDTSRPESVVIITREVESSL----------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3UVU3-1", "uniprot_id": "ZNT10_MOUSE", "id": "Q3UVU3-1", "name": "Calcium/manganese antiporter SLC30A10", "aln": "---MGRYSGKTCRLLFMLVLTAAFFVAELVSGYLGNSIALLSDSFNMLSDLISLCVGLGSGYIARRGPRGS------------------------------------SATYGYVRAEVVGALSNAVFLTALCFTIFVEAVLRLARP---ERIDDPELVLIVGALGLAVNVVGLLIFQ-------DCGACFSRCTRGR--RTRPSQQPSQGDPRGALGCP-------------QEAATATAPGSGTAVTLRGSSAGRKQQEGATVFSNVAGDSLNTENEPEETTKKEKKSEALNIRGVLLHVMGDALGSVVVVITAIIFYVQPLRRE------DPCN--------------------------WQCYIDPSLTVVMVIIILSSAFPLIKETAVILLQMVPKGVNMEELMS-QLSTVPGISSVHEVHIWELISGKIIATLHIKHQKGT----EYQDASRKIREIFHHAGIHNVTIQFETLD-------------------------------------------------------LKEALEQKDFLLTCSAPCITQSCAKKLCCPPGTLPLALVNGCAEHNGRSSRESYRS-----IEAPEVAIDV--DGCPREQGQTLSKTQERQHYENSTHF---------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZJB7-1", "uniprot_id": "D3ZJB7_RAT", "id": "D3ZJB7-1", "name": "", "aln": "---MGRYSGKTCRLLFMLVLTAAFFVAELVSGYLGNSIALLSDSFNMLSDLISLCVGLGSGYIARRGPRGS------------------------------------SATYGYVRAEVVGALSNAVFLTALCFTIFVEAVLRLARP---ERIDDPELVLIVGALGLAVNVVGLLIFQ-------DCGACFSRCTRGH--RTRPSQPPRQGDTGGALGCP-------------REAATATDPGSDSAVTLRGASAGRKQQEGATVFSNVAGDSLNTQNEPEETTKKEKKSEALNIRGVLLHVMGDALGSVIVVVTAIIFYVRPLRHE------DPCN--------------------------WQCYIDPSLTVVMVIIILSSAFPLIKETAVILLQMVPKGVNMEELMS-QLSMVPGVSSVHEVHIWELISGKVIATLHIKHQEGT----EYQDASRKVREIFHHAGIHNVTIQFETLD-------------------------------------------------------LKEALEQKDFLPTCSAPCISQSCAKKLCCPPGTLPLALVNGCAEHNGGPNLESYRS-----IEAPEVVIDVALDGCPRKQGQVHSKTQERQHCENSTHF---------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6XR72-4", "uniprot_id": "ZNT10_HUMAN", "id": "Q6XR72-4", "name": "Calcium/manganese antiporter SLC30A10", "aln": "---MGRYSGKTCRLLFMLVLTVAFFVAELVSGYLGNSIALLSDSFNMLSDLISLCVGLSAGYIARRPTRGF------------------------------------SATYGYARAEVVGALSNAVFLTALCFTIFVEAVLRLARP---ERIDDPELVLIVGVLGLLVNVVGLLIFQ-------DCAAWFACCLRGRSRRLQQRQQLAEGCVPGAFGGPQGAE-------DPRRAADPTAPGSDSAVTLRGTSVERKREKGATVFANVAGDSFNTQNEPEDMMKKEKKSEALNIRGVLLHVMGDALGSVVVVITAIIFYVLPLKSE------DPCN--------------------------WQCYIDPSLTVLMVIIILSSAFPLIKETAAILLQMVPKGVNMEELMS-KLSAVPGISSVHEVHIWELVSGKIIATLHIKYPKDR----GYQDASTKIREIFHHAGIHNVTIQFENVD-------------------------------------------------------LKEPLEQKDLLLLCNSPCISKGCAKQLCCPPGALPLAHVNGCAEHNGGPSLDTYGSDGLSRRDAREVAIEVSLDSCLSDHGQSLNKTQEDQCYVNRTHF---------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IEQ2-1", "uniprot_id": "A0A0R4IEQ2_DANRE", "id": "A0A0R4IEQ2-1", "name": "", "aln": "---MGRYSGKTCRLILMLVITVIFFVAEIVAGYMGNSVALVSDSFNMLSDILSLCVGLTAARVSRRAGSG-------------------------------------RFSFGLGRAEVVGALANAVFLIALCFSISMESLKRLAMP---QAIDDAPLVLIVGSLGLAVNLVGLVIFQ-------DCGRLCGR--RGK---EKKREEHRE----------------------------------DREQELEQVETGLQEE------------------------KTEKDGAPLNIRGVLLHVLNDALGSVVVVVASALFYVWPLEPD------QPCN--------------------------WQCYVDPSLTLVMVIIILSSAAPLLKETTTILLQMSPEDLPVSAILE-SVCRLPGVSSVHEAHVWELAKGRNVASLHVKLQAPAGALWAQVSLQQQITQIFHRAGVHSLTLQLELAD-------------------------------------------------------SDADS-------SCSAPCLSSSCQKLSCCPAG-----PVCVCAPPRDSS-----------------------------------TEKHTPQACTHSSKL---------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32798-1", "uniprot_id": "COT1_YEAST", "id": "P32798-1", "name": "Vacuolar zinc transporter COT1", "aln": "----MKLGSKQVKIISLLLLDTVFFGIEITTGYLSHSLALIADSFHMLNDIISLVVALWAVNVAKNRNPDS------------------------------------TYTYGWKRAEILGALINAVFLIALCVSILIEALQRIIAP---PVIENPKFVLYVGVAGLISNTVGLFLFHDNDQ-EHGHGHGHSHGGIFADHEMHMPSSHTHTHAHVDGIENTTPM---------DSTDNISEIMPNAIVDSFMNENTRLLTPENASKTPSYSTSSHTIASGGNYTEHNKRKRSLNMHGVFLHVLGDALGNIGVMLSAFFIWKTDYSWK--------------------------------------YYTDPLVSLIITGIIFSSALPLSCKASKILLQATPSTLSGDQVEG-DLLKIPGIIAIHDFHIWNLTESIFIASLHIQLDISPEQ---FTDLAKIVRSKLHRYGIHSATLQPEF---------------------------------------------------------ITREVTSTERAGDSQGDHLQNDPLSLRPKTYGTGISGSTCLIDDAANCNTADCLEDH---------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "M9PEG6-1", "uniprot_id": "M9PEG6_DROME", "id": "M9PEG6-1", "name": "", "aln": "---MAKYSGKKCRLLSMMWLTAFFFFVEIIVGYVTNSMALVADSFHMLGDIAALVISFLSVKMSPKK--WS------------------------------------KNTFGWARAEVLGALVNAVFLVALCFSITIEACKRFIEE---EPIHEPELLVIVGALGLLVNVIGLCLLY-----EHGGHHGHSHG-----------GGLTRNHSRLTELANMDEG---------EDEQ-----------NDFAYEKQKEKAPVKKSSHG-----------------HSHDPGQMNMRGAFLHVLSDALGSIIVVISAVVVWKTEWKYR--------------------------------------YYMDPALSIVLVVLILHSVWPLLRESALILLQTVPTHIQVDAIQKRLLEKVDGVLAVHEFHVWQLAGDRIIASAHIRCRN-LSE---YMKIAEKVKEFFHNEGIHSTTIQPEFSEIEGCNMSDGTSSINISGSDCCALDCPTTEEGCVKATCCQNNNKLNQLPSPTNSPYLCRQRNAARQAGDVEAGSLLEATSSGNQGATGGASTGAPVAAIGATSTPKSDLVXRQPHQAQQHVHFATTKTETATATTKAATTAAATSIRDIMYEPRANNLVVSSAQVDVNLGLTVTAQRRRELQLQAEQQYQEQVSPLSTRNGDEVAL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPE3-1", "uniprot_id": "Q9VPE3_DROME", "id": "Q9VPE3-1", "name": "", "aln": "MVKDILQRCKPIPLYTVLVLSICYFVLQLILSHLTHGLTLLMASHHMLCNIFALGGCIITIKHSKQAPEARNPSPALTKINGSGVAISLADTDAQTRAKRECREQKLRNTFGWARIDILTMLIVFIILASLSFSLVVEALQTLVHIDHQDTMHLPIPVMMLGFIGLILNGLTYLLIG---------GYTLHQG----------SFLHLTPGGNVVLERPMS-----------------------SNLDLSLTPMQRHLSKSRNDRQLR-----------EELETEVGSVYFATKRQGAVEMLRDVSSTIFVIVCAAIVYVAEDEQHT------------------------------------AKFIDPVLSIFSCVLLVTLSYPYMKESCLILLQTIPGSIDLEIFERTLVTKFPEIISYHDLHIWQLAAHRYVATIHIQFQNPK----LYLKIIEQVRSYFHDQGIGAVTIQPEFYP---------------------------------------------------------STNKNASASLECLMQCQAVECIEKVCCRDSRTDLREVCDAPSGRKSSSPVKCAGNSHEHSRAKSKSCAELSAVVVEKPEELSAGQLLKGQDQQVAKSMPKLEETCVDATKEDTAELSGSPPGPTSSD---------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: : :: :: . : .:::: *.:** :: :* : : : . ::* * ::: * ::* .*..:: :*: : :. . :: :* ** * : :: . : :.:: *. ..: *:: : .. : ** : :. ::. * :: **** * : . : . : *: *:*:* :*: *:: . : . :* *: *:* * ", "identical_positions": 35, "similar_positions": 91, "identity": "5.12%" }, { "cls_id": "homologset.agr.SGD:S000005844", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CZW4-1", "uniprot_id": "ACSL3_MOUSE", "id": "Q9CZW4-1", "name": "Fatty acid CoA ligase Acsl3", "aln": "MNNHVSSTPSTMKLKQTINPILLYFIHFIISLYTILTYIPFYFLC----ESKQEKPNQIKAKPV----------------------SSKPDSAYRSIN-SVDGLASVLYPGCDTLDKVFMYAKNKFKNKRLLGTREILNEEDEIQPNGKIFKKVILGHYNWLSYEDVFIRALDFGNGLQMLGQKPKAN--IAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHGLNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKP------------------PTWSEFPKGVIVHTMAAVQALGVKANVEKKAHSKPLPSDIAVIMYTSGSTGIPKGVMISHSNIIASITG-MARRIPRLGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSVLKPTLMAAVPEIMDRIYKNVMNKVNEMSAFQRNLFILAYNYKMEQISKGCS-TPLCDRFVFRNVRRLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESTGAGTITEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKTDFFEDENGQRWLCTGDIGEFDPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLIDNICAYANSYHSYVIGFVVPNQKELTELARTKGFKG------TWEELCNSSEMENEVLKVLSEAAISASLEKFEIPLKIRLSPDPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63151-1", "uniprot_id": "ACSL3_RAT", "id": "Q63151-1", "name": "Fatty acid CoA ligase Acsl3", "aln": "MNNHVSSTPSTMKLKQTIHPILLYFIHFIISLYTILTYIPFYFLC----ESKQEKPNHIKAKPV----------------------SSKPDSAYRSVN-SMDGLASVLYPGCDTLDKVFMYAKNKFKDKRLLGTREILNEEDEIQPNGKVFKKVILGHYNWLSYEDVFIRALDFGNGLQMLGQKPKAN--IAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHGLNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKP------------------PTWSEFPKGVIVHTMAAVQALGVKADVDKKAHSKPLPSDIAVIMYTSGSTGIPKGVMISHSNIIASITG-MARRIPRLGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSVLKPTLMAAVPEIMDRIYKNVMNKVNEMSAFQRNLFILAYNYKMEQISKGCS-TPLCDRFVFRNVRRLLGGNIRVLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESTGAGTITEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFDPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLIDNICAYANSYHSYVIGFVVPNQKELTELARTKGFNG------TWEELCNSSEMENEVLKVLSEAAISASLEKFEIPLKIRLSPDPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95573-1", "uniprot_id": "ACSL3_HUMAN", "id": "O95573-1", "name": "Fatty acid CoA ligase Acsl3", "aln": "MNNHVSSKPSTMKLKHTINPILLYFIHFLISLYTILTYIPFYFFS----ESRQEKSNRIKAKPV----------------------NSKPDSAYRSVN-SLDGLASVLYPGCDTLDKVFTYAKNKFKNKRLLGTREVLNEEDEVQPNGKIFKKVILGQYNWLSYEDVFVRAFNFGNGLQMLGQKPKTN--IAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKP------------------PTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNIIAGITG-MAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQISKGRN-TPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKG------TWEELCNSCEMENEVLKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TXZ5-1", "uniprot_id": "A0AB32TXZ5_DANRE", "id": "A0AB32TXZ5-1", "name": "long-chain-fatty-acid--CoA ligase", "aln": "-----------MKLKEDMSPLLLQVFRSVVWVYSVITFLPWYLLSGASGN--QARAKRVKARAI----------------------NGNPAGPYRAVN-SQLKLASLLHEGVDTLDKVFEYAVVHFPERDCLGTRELLSEEDEIQPNGKVFKKVILGDYNWLSYQDTFHLAQRFGSGLAALGQKPLCN--IAIFCETRAEWVIAAQACFMYNFPLVTLYSTLGGSAIAHGLNETEVTHIVTSKDLLQSRLKAILLEVPRLKHIIVVDTKP------------------TSWPDLPRGIMVHNMAAVQELGSKPENIMVSRRQPVPSDIAVIMYTSGSTGIPKGVMISHSNIIAGITG-MAERIPNLDENDTYIGYLPLAHVLELSAELVCVSHGCRIGYSSPQTLADQSSKIKKGSKGDTSVLKPTLMAAVPEIMDRIYKNVMTKVEEMSSVQKTLFVLAYNYKMEQISKGYT-TPLCDRLVFRKVRSLLGGNTRVLLSGGAPLSAATQRFMNICFCCPVGQGYGLTETCGAGTISEMSDYSTGRVGAPLVCSEIMLKDWEEGGYFGTDKPNPRGEILIGGPNVTMGYYKNEQKNREDFFEDKNGQRWFCTGDIGEFHPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAVLKNCPLIDNICAYANSDESYVIGFVVPNQKQLTALAGQKGIRG------SWEEICNHAEMEKEVLRIITDAAISGKLERFEIPKKICLSAEPWTPETGLVTDAFKLKRKELKTHYQDDIERMYGGK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1LVA8-1", "uniprot_id": "Q1LVA8_DANRE", "id": "Q1LVA8-1", "name": "long-chain-fatty-acid--CoA ligase", "aln": "-----------MRLTQDLSPAVVLVFRLVVWLYSLISYLPYLLLRSPESQSLSECSRRLKARSV----------------------SGDPAGPYRDVA-ALKGLEMCLHPGINTLDQVFQSSVSHFPNSDCLGTRELLSEEDETQEDGKVFKKVILGEYRWMSYEQVFKEVNAFGSGLAALGQKPMKN--IAIFCETRAEWIIAAQACFMYNFPLVTLYSTLGGPAIAHGLNEAEVSHIITSKDLLETKLKSIFIEVPRLCHVIVVDDKL------------------STSSEYPRGISIHSMASVKELGARPENASKPKNPPCSSDVAVIMYTSGSTGVPKGVMISHSNIISGITG-MTHRIPKLVEDDTYIGYLPLAHVLELSAEMVCLAHGCRIGYSSPQTLSDQSTKIKKGSRGDISVLRPTLMAAVPEIMDRIYKNVMLRVEQMSGFQRTLFLLAYNYKMEQLAMGYS-TPLCDKLVFRKVRALLGGRLRVLLSGGAPLSAATQRFMNICFCCPVGQGYGLTETCGAGTISHLWDYSTGRVGAPLVCCELQLKDWIEGGYHSTDLPCPRGEILVGGPSITMGYYKNTHKTSEDFFVDKKGQRWFCTGDIGEIHGDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLVDNICAYANSDESYVIGFVVPNQKQLLALAERKRVRG------LWEELCNNPVIEEAVLTVLTEAALTAQLERFEIPRKIRLSVEPWTPDTGLVTDSFKLKRKELKTHYQNDIERMYGAK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9QUJ7-1", "uniprot_id": "ACSL4_MOUSE", "id": "Q9QUJ7-1", "name": "Long-chain-fatty-acid--CoA ligase 4", "aln": "-----------MNLKLNVLTIILLPVHLLITIYSALIFIPWYFLTN--AKKKNAMAKRIKAKPT----------------------SDKPGSPYRSVT-HFDSLAVIDIPGADTLDKLFDHAVAKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWINYLEVNCRVNNFGSGLTALGLKPKNT--IAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGREAVVHGLNESEASYLITSVELLESKLKAALVDINCVKHIIYVDNKT------------------INRAEYPEGLEIHSMQSVEELGAKPENLSVPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTG-QCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYVQKTLFKIGYDYKLEQIKKGYD-APLCNLILFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTVHDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYCVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKKLTLLAQQKGVEG------SWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELKNHYLKDIERMYGGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35547-1", "uniprot_id": "ACSL4_RAT", "id": "O35547-1", "name": "Long-chain-fatty-acid--CoA ligase 4", "aln": "-----------MKLKLNVLTIVLLPVHLLITIYSALIFIPWYFLTN--AKKKNAMAKRIKAKPT----------------------SDKPGSPYRSVT-HFDSLAVIDIPGADTLDKLFDHAVAKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWINYLEVNCRVNNFGSGLTALGLKPKNT--IAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKAALLDINCVKHIIYVDNKT------------------INRAEYPEGLEIHSMQSVEELGSKPENSSIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTG-QCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYD-APLCNLILFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTVHDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKKLTLLAQQKGVEG------SWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELKNHYLKDIERMYGGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60488-1", "uniprot_id": "ACSL4_HUMAN", "id": "O60488-1", "name": "Long-chain-fatty-acid--CoA ligase 4", "aln": "-----------MKLKLNVLTIILLPVHLLITIYSALIFIPWYFLTN--AKKKNAMAKRIKAKPT----------------------SDKPGSPYRSVT-HFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKPKNT--IAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKA------------------INKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTG-QCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYD-APLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEG------TWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKDIERMYGGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KFE4-1", "uniprot_id": "A0A0B4KFE4_DROME", "id": "A0A0B4KFE4-1", "name": "long-chain-fatty-acid--CoA ligase", "aln": "-------------MDSFWVQSAIGAIKAIAFVYDIITLPVYLVLQKP--WKRRQDSRRVKAKPINQKMLVDESKYAPDDIEAKIVRNDDNELTYRTTDPPRDVHVKMLQENIDTLEKVFNYVAKTYTSKRCLGTRQILSEEDEVQQNGRVFKKYNLGDYKWKTFTEAERTAANFGRGLRELGQKPREN--IVIFAETRAEWMIAAHGCFKQAMPIVTVYATLGDDGVAHCITETEVTTVITSHDLLP-KFKTLLDKCPLVKTIIYIEDQLQK----------------TETTGFKEGVKILPFNQVVKTGQDSKFEHVP---PKGDDIAIIMYTSGSTGTPKGVLLSHKNCIATMKG-FVDMVP-IYPDDVLIGFLPLAHVFELVAESVCLMTGVPIGYSTPLTLIDTSSKIKRGCKGDATVLKPTCMTSVPLILDRISKGINDKVNSGSAFKKSLFKFLYQYKVKWVQRGYK-TPLIDKLVFKKVAKLMGGKVRIIMSGGAPLSADTHEQIKTCLCLELIQGYGLTETTSGATVMDYRDMTYGRTGGPLTVCDIRLVNWEEGNYRVTNKPYPQGEVLIGGECVSQGYYKLPGKTNEDFFE-EDGQRWFKTGDIGEIQADGVLKIIDRKKDLVKLQAGEYVSLGKVESELKTCGIIENICVYGDPTKQYTVALVVPNQNHLEELAQKHGLGDK-----SFEELCSSPIIEKAILKEIAEHARKCKLQKYEVPAAITLCKEVWSPDMGLVTAAFKLKRKDIQDRYQHDINRMYAS-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P30624-1", "uniprot_id": "LCF1_YEAST", "id": "P30624-1", "name": "Long-chain-fatty-acid--CoA ligase 1", "aln": "----------------------------MVAQYTVPVGKAANEHETAPRRNYQCREKPLVRPPN-----------------------TKCSTVYEFVLECFQKNKNSNAMGWRDVKEIHEESKSVMKKVD-----------GKETSVEKKWMYYELSHYHYNSFDQLTDIMHEIGRGLVKIGLKPNDDDKLHLYAATSHKWMKMFLGAQSQGIPVVTAYDTLGEKGLIHSLVQTGSKAIFTDNSLLPSLIKPVQAAQD-VKYIIHFDSISSEDRRQSGKIYQSAHDAINRIKEVRPDIKTFSFDDILKLGKESCN-EIDVHPPGKDDLCCIMYTSGSTGEPKGVVLKHSNVVAGVGGASLNVLKFVGNTDRVICFLPLAHIFELVFELLSFYWGACIGYATVKTLTSSS---VRNCQGDLQEFKPTIMVGVAAVWETVRKGILNQIDNLPFLTKKIFWTAYNTKLNMQRLHIPGGGALGNLVFKKIRTATGGQLRYLLNGGSPISRDAQEFITN-LICPMLIGYGLTETCASTTILDPANFELGVAGDLTGCVTVKLVDVEELGYFAKNN---QGEVWITGANVTPEYYKNEEETS----QALTSDGWFKTGDIGEWEANGHLKIIDRKKNLVKTMNGEYIALEKLESVYRSNEYVANICVYADQSKTKPVGIIVPNHAPLTKLAKKLGIMEQKDSSINIENYLEDAKLIKAVYSDLLKTGKDQGLVGIELLAGIVFFDGEWTPQNGFVTSAQKLKRKDILNAVKDKVDAVYSSS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . : . . *. . :.::. . .: : : *..*.: .: : :* ** :* ** : ::. * :*: . : :** * *** .: * : :: . :.*. .** :* : :* .: .. : : * . * .*:. :******** ****:: *.* :: : * : : * * :*****::** * .. * ***:: ** . * :..:** ::** *..*. : : : *.: ::.. . :.:* *: *:: . ::*::: **. * :: **:*:* ::. :. : : ******: .. *: . : * .* : * : * .* : :**: : * :: *:* :. .: *: ****** . :* *:******:*** ***::* *:*: :. : ***.:.. . :.::***: * ** . : . : : : . . * *: : : *:*: *:** : *****:: .:: :*. ", "identical_positions": 140, "similar_positions": 183, "identity": "18.06%" }, { "cls_id": "homologset.agr.SGD:S000005846", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYL5-1", "uniprot_id": "SF3B4_RAT", "id": "Q6AYL5-1", "name": "Splicing factor 3B subunit 4", "aln": "MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIMN-MIKLYGKPIRVNKASAHNKNLDVG-----------ANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKG-ERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAGGHGPPAAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGY-TGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRGPLPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8QZY9-1", "uniprot_id": "SF3B4_MOUSE", "id": "Q8QZY9-1", "name": "Splicing factor 3B subunit 4", "aln": "MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIMN-MIKLYGKPIRVNKASAHNKNLDVG-----------ANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKG-ERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAGGHGPPAAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGY-TGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRGPLPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15427-1", "uniprot_id": "SF3B4_HUMAN", "id": "Q15427-1", "name": "Splicing factor 3B subunit 4", "aln": "MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIMN-MIKLYGKPIRVNKASAHNKNLDVG-----------ANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKG-ERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGY-TGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRGPLPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NWB3-1", "uniprot_id": "Q6NWB3_DANRE", "id": "Q6NWB3-1", "name": "Splicing factor 3B subunit 4", "aln": "MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIMN-MIKLYGKPIRVNKASAHNKNLDVG-----------ANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKG-ERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSMPTPVMTALGAAMPIPGMPPPGAFPP-VPPPGTMPPGMPPGMP---MPPAPGTPAPQGGGGPPPGHP--------PFPPAGMHPPGMPHMPMPPTGPPGMVPPPPGPPGSN-QPRAPPPPQMP---PPPMGVPPRGP-FGPPMGPP--MHP-GMRGPPPPMPPPGYGAGPPRPPPFGFQRGPPMPPRPP-----APRGPMRAPAPS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W424-1", "uniprot_id": "Q9W424_DROME", "id": "Q9W424-1", "name": "Splicing factor 3B subunit 4", "aln": "MAAGPIAERNQDATIYAGGLDDKVSETLLWELFVQAGPVVNVHMPKDRVTQMHQGYGFVEFLSEEDADYGIKIMN-MIKLYGKPIRVNKASAHQKNLDVG-----------ANIFIGNLDVEVDEKLLYDTFSAFGVILQTPKIMRDPETGKSKSFAFINFASFEASDAAMDAMNGQYLCNRPISVSYAFKKDHKG-ERHGSAAERLLAAQNPSTHADRPHQLFADAPVQTMMP-QMPGQIPAQMPGQMMPPPMMAPP--------PPVVPVSNN------NMGMLAPP--------------------PPVPQPAP------FPATIP-----PPPLPPMTGGQPPLPPAMGIP---PPPR------------MMQPNAWAPPGMPAPPPRPPPTNW-----RPPPVPFP--PTPYARPY-----QPDGYQY-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99181-1", "uniprot_id": "HSH49_YEAST", "id": "Q99181-1", "name": "Protein HSH49", "aln": "----MNYSADSGNTVYVGNIDPRITKEQLYELFIQINPVLRIKYPKDKVLQAYQGYAFIEFYNQGDAQYAIKIMNNTVRLYDRLIKVRQVTNSTGTTNLPSNISKDMILPIAKLFIKNLADSIDSDQLVKIFNKFGKLIREPEIFYLSNG--KLKCAYVYFEDFEKADLAIKSLNNQLVANNRITVDYAFKENGKGNAKYGDDVDRLLNKEALKHNMLK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.. *:*.*.:* :::: *:***:* .**:. : ***:* :***.*:** .: **:*.***** ::**.: *:*.:.: . :: *::** ** .:*.. * . *. ** ::: *:*: .: . *:: * .*: :* *:.::*.* :.*. *:*.****:: ** ::*. .:*** : : : ", "identical_positions": 65, "similar_positions": 79, "identity": "14.84%" }, { "cls_id": "homologset.agr.SGD:S000005848", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGQ4-1", "uniprot_id": "POMT2_MOUSE", "id": "Q8BGQ4-1", "name": "Protein O-mannosyl-transferase 2", "aln": "MLYASGRLLAARAATTLSAPPRARGPALRGKRRELQIPWHLETPSYDPLTGQRTRPGVPPARRVILRKGRMPPAIGGGLAGSELRPRRGRCVPQAARAVSRDVVPQAAARKLKRPAWSSRRFQAAGWWATLAVVTLLSFATRFHRLDQPAHICWDETHFGKMGSYYINRTFFFDVHPPLGKMLIGLAGYLSGYDGTFLFQKPGDRYEHHSYMGMRGFCAFLGSWLIPFAYLTVLDLSKSFPAALLTAALLTFDTGCLTLSQYILLDPILMFFIMAAMLSMVKYN--SCANRPFSAPWWFWLSLTGISLAGALGVKFVGLFIIVQVGLNTISDLWHLFGDLSLSLVTVGKHLTARILCLIVLPLVLYVTIFAVHVMVLNKSGPGDGFFSSAFQARLSGNSLHNASIPEHLAYG-SVITVKNLRMAIGYLHSHRHLYPEGIGARQQQVTTYLHKDYNNLWIIKKYNANTDPLDPSFP-VEFVRHGDIIRLEHKETTRNLHSHYHEAPLTRKHYQVTGYGINGTGDSNDFWRIEVVNRKFGNR---IKVLRSRIRLIHLVTGCVLGSSGKILPKWGWEQLEVTCTPYLKETT-NSIWNIEEHINPKLPN-ISLDVLQPSFPEILLESHMVMIRGNNGLKPKDNEFT---SKPWHWPINYQGLRFSGANDTDFRVYLLGNPVVWWLNLVSIVLYLLSGSTIAVAMQRGIQLPAELQG-----------------------------------------------LTKVLLRGGGQLLLGWMLHYFPFFLMGRILYFHHYFPAMLFSSMLTGILWDTLLRLCAWGLAPSPLGRRIHAVGILSLLLTTAYSFYLFHPLAYGMVGPLAQEPESPMAGLRWLESWDF-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14U74-1", "uniprot_id": "Q14U74_RAT", "id": "Q14U74-1", "name": "Dolichyl-phosphate-mannose--protein mannosyltransferase", "aln": "MFYASGRLLAAREATTLYAPPRARGPALRGKRRELQIPWHLETPSYDSLTGQRTRPGVPPARRVILRKGRMPPAIGGGLAGSELRPRRGRSVQQAARAVSRDVVPEAATRKLKRPAWSSRRFQAAGWWATLAVVTLLSFATRFHRLDQPAHICWDETHFGKMGSYYINRTFFFDVHPPLGKMLIGLAGYLSGYDGTFLFQKPGDRYEHHSYMGMRGFCAFLGSWLIPFAYLTVLDLSKSFPAALLTAALLTCDTGCLTLSQYILLDPILMFFIMAAMLSMVKYN--SFANRPFSAPWWFWLSLTGISLAGALGVKFVGLFIIVQVGLNTISDLWHLFGDLSLSLVTVGKHLTARILCLIVLPLVLYVTIFAVHVMVLNKSGPGDGFFSSAFQARLSGNSLHNASIPEHLAYG-SVITVKNLRMAIGYLHSHRHLYPEGIGARQQQVTTYLHKDYNNLWIIKKYNTNTDPLDPSFP-VEFVRHGDIIRLEHKETTRNLHSHYHEAPLTRKHYQVTGYGINGTGDSNDFWRIEVVNRKFGNR---IKVLRSRIRFIHLVTGCVLGSSGKILPKWGWEQLEVTCNPYLKETS-NSIWNIEEHINPKLPN-ISLDVLQPSFPEILLESHMVMIRGNNGLKPKDNEFT---SKPWHWPINYQGLRFSGANDTDFRVYLLGNPVVWWLNLVSLVLYLLTGSTIAIAMQRGIQLPAELQG-----------------------------------------------LTKLLLRGGGQLLLGWTLHYFPFFLMGRVLYFHHYFPAMLFSSMLTGLLWDTLLRFCAWALAPSPLGRRIHMVGILSLLLATAYSFYLFHPLAYGMVGPLAQEPESPMAGLRWLESWDF-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UKY4-1", "uniprot_id": "POMT2_HUMAN", "id": "Q9UKY4-1", "name": "Protein O-mannosyl-transferase 2", "aln": "----------------------------------------------------------------------MPPATGGGLAESELRPRRGRCGPQAARAAGRDVAAEAVARSPKRPAWGSRRFEAVGWWALLALVTLLSFATRFHRLDEPPHICWDETHFGKMGSYYINRTFFFDVHPPLGKMLIGLAGYLSGYDGTFLFQKPGDKYEHHSYMGMRGFCAFLGSWLVPFAYLTVLDLSKSLSAALLTAALLTFDTGCLTLSQYILLDPILMFFIMAAMLSMVKYN--SCADRPFSAPWWFWLSLTGVSLAGALGVKFVGLFIILQVGLNTIADLWYLFGDLSLSLVTVGKHLTARVLCLIVLPLALYTATFAVHFMVLSKSGPGDGFFSSAFQARLSGNNLHNASIPEHLAYG-SVITVKNLRMAIGYLHSHRHLYPEGIGARQQQVTTYLHKDYNNLWIIKKHNTNSDPLDPSFP-VEFVRHGDIIRLEHKETSRNLHSHYHEAPMTRKHYQVTGYGINGTGDSNDFWRIEVVNRKFGNR---IKVLRSRIRFIHLVTGCVLGSSGKVLPKWGWEQLEVTCTPYLKETL-NSIWNVEDHINPKLPN-ISLDVLQPSFPEILLESHMVMIRGNSGLKPKDNEFT---SKPWHWPINYQGLRFSGVNDTDFRVYLLGNPVVWWLNLLSIALYLLSGSIIAVAMQRGARLPAEVAG-----------------------------------------------LSQVLLRGGGQVLLGWTLHYFPFFLMGRVLYFHHYFPAMLFSSMLTGILWDTLLRLCAWGLASWPLARGIHVAGILSLLLGTAYSFYLFHPLAYGMVGPLAQDPQSPMAGLRWLDSWDF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q8R9-1", "uniprot_id": "POMT2_DANRE", "id": "F1Q8R9-1", "name": "Protein O-mannosyl-transferase 2", "aln": "----------------------------------------MDVRPKENFS--------------------QRQDTSAVRHRKTCKVNERAEIPSQPHNGTINGVNKRITKREGGEHISSPSRDAHVPVFILALVIVLSVSTRFYKITEPPHVCWDETHFGKMGSYYINRTFFFDVHPPLGKMLIGLAGYLTGYDGTFPFIKPGDKYEHHNYWGMRAFCAALGSCLPPFAFLVVLELSQSSTAALIAASLLIFDTGCITLSQYILLDPILMFFIMGSVLCMVKFN--TQRLGPFSFSWWFWLLLTGLCLSGSLGVKFVGLFVILLVGINTALDLWRLLGDLSLSLVDFGKHLLARVFGLIMLPLFLYTTIFAIHFIVLNRSGPGDGFFSSAFQSRLIGNNLHNASMPEYLAYG-SVITVKNLRIAGGYLHSHWHLYPEGVGAHQQQVTAYLHKDYNNLWLVKRLD-NSDDLTGSP---ELVRHGDIIRLEHKETTRNLHSHFHEAPLTKKHLQVTGYGINGSGDVNDLWQVEVCGGRKGDP---VKVLRSKVRFLHRATGCVLCSSGKTLPKWGWEQVEVTCSPYVKETP-NSQWNIEDHINPKLPN-ISLAVLKPTFLEILWESHIVMIRGNSGLKPKDNEMN---SKPWHWPINYQGLRFSGVNETEYRVYLLGNPVIWWLNLLSLALFVILLTVASLAVQRRVKMEGMMKV-----------------------------------------------HCHTLMEGGGMLFLGWLLHYLPFYIMGRILYYHHYFPAMMFSSMLTGITLDILLQNLQLLFSSS-LSHYLMRGGQSVLLLGFIYSFYLFHPLSYGMRGPLAHDSASSMAGLRWMESWEF-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W5D4-1", "uniprot_id": "POMT2_DROME", "id": "Q9W5D4-1", "name": "Protein O-mannosyl-transferase 2", "aln": "------------------------------------------------------------------------------MAASVVKT------PKCPRRGSVKDVAQNAPRTAP----TSSKEANWNWWLLLATVFLVTFATRFYKVTEPDHICWDETHFGKMGSWYINRTFFFDVHPPLGKMLIGLSGYLTGYNGTFPFEKPGDKYNETRYQGMRYFCTTLGALIMPMGFDTVYDLTRSHEAALLAAAYLIFDVGLLTLNQYILLDPILLFFMMASVWGMVKVSKSTASGGSYGLRWWLWLFLTGTMLSCTISVKFVGLFVVLLVGLHTATELWLILGDLGQPILETVKQLACRAITLIVWPVLLYILFFYIHLSVLNRSGNGDGFYSSAFQSRLIGNSLYNASMPRDVAYG-SLVTIKNHKTGGGYLHSHHHLYPKGSGARQQQVTTYTHKDENNKWLIRPHN---KPGPPKGK-VQILRHGDLVRLTHMATRRNLHSHNEPAPMTKKHLQVTGYGELGLGDANDVWRVLIVGGKVNET---VHTVTSRLKFIHLLQNCALTSSGKQLPKWGFEQQEVSCNPNVRDK--NSQWNVEDNEHKLMPS-VSFSVYAPGFFARFLESHAVMLQGNAGLKPKEGEVT---SRPWQWPINYRGQFFSGS---SYRIYLLGNPLIWWSNLVFLALFVTVFLCNAVVQQRRAGFARSAAQNQAQVPDSETVAQDEESEHSTTDICSCCTPAKEIVPKAVPSGSPEAPNPAQSLRAAAWLFLGWMLHYLPFWAMGRVLYFHHYFPALIFNSLLTGVMYNYILR---------VLPKWIHHVILGLVLSILVYSFAAFSPLAYGMSGPLANEPNSTMYNLKWLSTWEF-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47190-1", "uniprot_id": "PMT3_YEAST", "id": "P47190-1", "name": "Dolichyl-phosphate-mannose--protein mannosyltransferase 3", "aln": "----------------------------------------------------------------------MPYRVATGYSEKSTDDDLIWRTPIVKEELEDADNFLKDDAELYDKVKNESAVSHLDTIVMPIIFTVLGMFTRMYKIGRNNHVVWDEAHFGKFGSYYLRHEFYHDVHPPLGKMLVGLSGYLAGYNGSWDFPSGEVYPDYIDYVKMRLFQAMFSSLCVPLAYFTGRAIGFSRLSVWLFTILVIFENSYATLGKFILLDSMLLFFTVSSYFCLAKFH--TMRKSPFSARWWLWLCLTGLNLGCAISVKMVGLFIISVVGIYTISELWNLLSDRSVSWKVYVNHWLARIFGLIIIPVCVFLLCFKIHFDLLSNSGPGDSTMPSLFQASLNGTKVGKG--PRDVALGSSIISIKNQALGGALLHSHVQPFPEG--SEQQQVTVYGYSDANNEWFFQRIRGVEPWTDAENKTIEFVKGGEMYRLMHRLTGKNLHTHEVPAPISKSEYEVSAYGDVDLGDYKDNWIIEIVEQVGEEDPTLLHPLSTSFRIKNSILGCYLAQSGKHLPEWGFRQGEVVCLKHASKRDKRTWWNIETHENERLPQGEDFVYPKTSFFRNFMQLNSAMMATNNALVPNPEKFDGIASSAWQWPTLNVGVRLCEWSEKSIKYFLLGSPASVWPSSIAVCALIIHVIFLTLKWQRQCVILSDPVER------------------------------------------------DVFVMAAFYPLLAWLLHYMPFVVMSRVVYAHHYLPTLYFALMILSYYFDMITKR----WATRNTGKFLRLGAYIVYGSIVIAGFFYFSPFSFGMDGPVDD-----YAYLAWLPTWQIVEDIRNT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . :: . **:::: . *: ***:****:**:*:.: *:.**********:**:***:**:*:: * . : * ** * : :.: *:.: . : * :. : : : : . **.::****.:*:** :.: :.* : .:. **:** *** *. ::.**:****:: **: * :** ::.* . . :: .* : **: *: :: * :*. :*..** **. .* **: * *..: :. *. :* * *::::** . . **** : :*:* :.*****.* :.* ** *:.: . :::: *:: ** * * :***:* **:::.. :*:.** . ** :* * : : : :: : : .:: : .* * .*** **:**:.* ** * . .: **:* : : :*. .: . * : : : .*: * .* *: :. * .*:** * :. . : :***.* * . : : : :: ** : : .. :*.* ***:** *.*::* ***:*:: * :: . : : : : : .* * *:::** **: . * *: :*:: ", "identical_positions": 184, "similar_positions": 215, "identity": "20.77%" }, { "cls_id": "homologset.agr.SGD:S000005849", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZPW1-1", "uniprot_id": "D3ZPW1_RAT", "id": "D3ZPW1-1", "name": "Arrestin domain-containing protein 2", "aln": "------------------------MLFDKVKAFVVELDGTRAGTEPVFHGGQAVAGRVLLELAGAARVGALRLRARGRARAHWTESRSAG--------SST-AYTQSYSERVEVVNHRATLLAPDSGD----------------------------------------------------------IVMLPAGRHEFPFSFQLPIS-LVTSFEGKHGSVRYSIKATLHRP-WVPAR------------------------RARKVFTVIEPVDIN--TPALLEPQAGAREKVARSWYCT--RGLVSLSAKIDRKG----------------------------------------------------------------------------YTPGE----------------------VIPIFAEIDNGS-TRAVQPRAALVQTQTFMARGARKQ-------------KCAVVASVDGEPVGPGRRALWP--GRALRIPPVGPSILHCR-VLSVDYSLKVCVDIPGSS-------------------KLLLELPLVIGTVPLHPLGSRSASVGSRASFLQDWGL----------------------------------------------------------------CALMERPEAPPEYSEVVRESPQVAASQGLFSFLHDPDVTTE-----------------------------------------GPYFACLQEFRYRP-------------------------------------PPLYSEEDPNP-PSEAARPRCMTC--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D668-1", "uniprot_id": "ARRD2_MOUSE", "id": "Q9D668-1", "name": "Arrestin domain-containing protein 2", "aln": "------------------------MLFDKVKAFVVEIDGARTGTEPVFHGGQAVAGRVLLELAGAARVGALRLRARGRARAHWTESRSAG--------SST-AYTQSYSERVEVVNHRATLLAPDSGD----------------------------------------------------------IATLPAGRHEFPFSFQLPIS-LVTSFEGKHGSVRYSIKATLHRP-WVPAR------------------------CARKVFTVIEPVDIN--TPALLEPQAGAREKVARSWYCT--RGLVSLSAKIDRKG----------------------------------------------------------------------------YTPGE----------------------VIPIFAEIDNGS-TRAVQPRAALVQTQTFMARGARKQ-------------KRAVVASVDGEPVGPNRRALWP--GRALRIPPVGPSILQCR-VLSVDYSLKVFVDIPGSS-------------------KLLLELPLVIGTVPLHPLGSRSASVGSRASFLQDWGL----------------------------------------------------------------CTMMDRPEAPPEYSEVVRESQLVCASPGPSSLLHDLGVTTE-----------------------------------------GPYFACLQEFRYCP-------------------------------------PPLYSEEDPNP-PSEAVRPRCMTC--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TBH0-1", "uniprot_id": "ARRD2_HUMAN", "id": "Q8TBH0-1", "name": "Arrestin domain-containing protein 2", "aln": "------------------------MLFDKVKAFSVQLDGATAGVEPVFSGGQAVAGRVLLELSSAARVGALRLRARGRAHVHWTESRSAG--------SST-AYTQSYSERVEVVSHRATLLAPDTGE----------------------------------------------------------TTTLPPGRHEFLFSFQLPPT-LVTSFEGKHGSVRYCIKATLHRP-WVPAR------------------------RARKVFTVIEPVDIN--TPALLAPQAGAREKVARSWYCN--RGLVSLSAKIDRKG----------------------------------------------------------------------------YTPGE----------------------VIPVFAEIDNGS-TRPVLPRAAVVQTQTFMARGARKQ-------------KRAVVASLAGEPVGPGQRALWQ--GRALRIPPVGPSILHCR-VLHVDYALKVCVDIPGTS-------------------KLLLELPLVIGTIPLHPFGSRSSSVGSHASFLLDWRL----------------------------------------------------------------GALPERPEAPPEYSEVVADTEEAALGQSPFPLPQDPDMSLE-----------------------------------------GPFFAYIQEFRYRP-------------------------------------PPLYSEEDPNP-LLGDMRPRCMTC--------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TPQ9-1", "uniprot_id": "ARRD3_MOUSE", "id": "Q7TPQ9-1", "name": "Arrestin domain-containing protein 3", "aln": "------------------------MVLGKVKSLTISFDCLNDSNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNAG--------SNT-AYTQNYTEEVEYFNHKDILIGHERDDDNSEE----------------------------------------------------GFHTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRP-WLLPV------------------------KLKKEFTVFEHIDIN--TPSLLSPQAGTKEKTLCCWFCT--SGPISLSAKIERKG----------------------------------------------------------------------------YTPGE----------------------SIQIFAEIENCS-SRMVVPKAAIYQTQAFYAKGKMKE-------------VKQLVANLRGESLSSGKTETWN--GKLLKIPPVSPSILDCS-IIRVEYSLMVYVDIPGAM-------------------DLLLSLPLVIGTIPLHPFGSRTSSVSSQCSMSMNWLA----------------------------------------------------------------LALPERPEAPPSYAEVVTE-EQRRNNLAPVGACDDFERALQ-----------------------------------------GPLFAYIQEFRFLP-------------------------------------PPLYSEIDPNPDQSSEDRPSCPSR--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6TXF1-1", "uniprot_id": "ARRD3_RAT", "id": "Q6TXF1-1", "name": "Arrestin domain-containing protein 3", "aln": "------------------------MVLGKVKSLTISFDCLNDSNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNAG--------SNT-AYTQNYTEEVEYFNHKDILIGHERDDDNCEE----------------------------------------------------GFSTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRP-WLLPV------------------------KLKKEFTVFEHIDIN--TPSLLSPQAGTKEKTLCCWFCT--SGPISLSAKIERKG----------------------------------------------------------------------------YTPGE----------------------SIQIFAEIENCS-SRMVVPKAAIYQTQAFYAKGKMKE-------------VKQLVANLRGESLSSGKTETWD--GKLLKIPPVSPSILDCS-IIRVEYSLMVYVDIPGAM-------------------DLLLSLPLVIGTIPLHPFGSRTSSVSSQCSMNMNWLG----------------------------------------------------------------LSLPERPEAPPSYAEVVTE-EQRRNNLAPVSACDDFERALQ-----------------------------------------GPLFAYIQEFRFLP-------------------------------------PPLYSEIDPNPDQSSEDRPSCPSR--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96B67-1", "uniprot_id": "ARRD3_HUMAN", "id": "Q96B67-1", "name": "Arrestin domain-containing protein 3", "aln": "------------------------MVLGKVKSLTISFDCLNDSNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNAG--------SNT-AYTQNYTEEVEYFNHKDILIGHERDDDNSEE----------------------------------------------------GFHTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRP-WLLPV------------------------KLKKEFTVFEHIDIN--TPSLLSPQAGTKEKTLCCWFCT--SGPISLSAKIERKG----------------------------------------------------------------------------YTPGE----------------------SIQIFAEIENCS-SRMVVPKAAIYQTQAFYAKGKMKE-------------VKQLVANLRGESLSSGKTETWN--GKLLKIPPVSPSILDCS-IIRVEYSLMVYVDIPGAM-------------------DLFLNLPLVIGTIPLHPFGSRTSSVSSQCSMNMNWLS----------------------------------------------------------------LSLPERPEAPPSYAEVVTE-EQRRNNLAPVSACDDFERALQ-----------------------------------------GPLFAYIQEFRFLP-------------------------------------PPLYSEIDPNPDQSADDRPSCPSR--------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J1F4-1", "uniprot_id": "ARRD4_MOUSE", "id": "A0A0B4J1F4-1", "name": "Arrestin domain-containing protein 4", "aln": "-------------MGGEAG---ADGPRGRVKSLGLVFEDESKG---CYSSGETVAGHVLLEAAEPVALRGLRLEAQGRATSAWGPSAGAR--------VCIGGGSPAASSEVEYLNLRLSLLEAPAGEG---------------------------------------------------------VTLLQPGKHEFPFRFQLPSEPLATSFTGKYGSIQYCVRAVLERP-QVPDQ------------------------SVRRELQVVSHVDVN--TPPLLTPMLKTQEKMVGCWLFT--SGPVSLSVKIERKG----------------------------------------------------------------------------YCNGE----------------------AIPIYAEIENCS-SRLVVPKAAIFQTQTYLASGKTKT-------------VRHMVANVRGNHIGSGSTDTWN--GKMLKIPPVTPSILDCC-IIRVDYSLAVYIHIPGAK-------------------RLMLELPLVIGTIPYSGFGRRNSSVASQFSMDMCWLA----------------------------------------------------------------LALPEQPEAPPNYADVVSE-EEFSRHVPPYPQPSDCDGEAC-----------------------------------------YSMFACIQEFRFQP-------------------------------------PPLYSEVDPHPGDAQETQPVSFIL--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCT1-1", "uniprot_id": "ARRD4_HUMAN", "id": "Q8NCT1-1", "name": "Arrestin domain-containing protein 4", "aln": "-------------MGGEAGCAAAVGAEGRVKSLGLVFEDERKG---CYSSGETVAGHVLLEASEPVALRALRLEAQGRATAAWGPSTCPR--------ASASTAALAVFSEVEYLNVRLSLREPPAGEG---------------------------------------------------------IILLQPGKHEFPFRFQLPSEPLVTSFTGKYGSIQYCVRAVLERP-KVPDQ------------------------SVKRELQVVSHVDVN--TPALLTPVLKTQEKMVGCWFFT--SGPVSLSAKIERKG----------------------------------------------------------------------------YCNGE----------------------AIPIYAEIENCS-SRLIVPKAAIFQTQTYLASGKTKT-------------IRHMVANVRGNHIASGSTDTWN--GKTLKIPPVTPSILDCC-IIRVDYSLAVYIHIPGAK-------------------KLMLELPLVIGTIPYNGFGSRNSSIASQFSMDMSWLT----------------------------------------------------------------LTLPEQPEAPPNYADVVSE-EEFSRHIPPYPQPPNCEGEVC-----------------------------------------CPVFACIQEFRFQP-------------------------------------PPLYSEVDPHPSDVEESQPVSFIL--------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BG60-1", "uniprot_id": "TXNIP_MOUSE", "id": "Q8BG60-1", "name": "Thioredoxin-interacting protein", "aln": "-----------------------MVMFKKIKSFEVVFND----PEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQG------------------SQQCKQTLDYLRYEDTLLLEEQPTAGENE----------------------------------------------------MVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGCVDYWVKAFLDRP-SQPTQ------------------------EAKKNFEVMDLVDVN--TPDLMAPVSAKKEKKVSCMFIP--DGRVSVSARIDRKG----------------------------------------------------------------------------FCEGD----------------------DISIHADFENTC-SRIVVPKAAIVARHTYLANGQTKV-------------FTQKLSSVRGNHIISGTCASWR--GKSLRVQKIRPSILGCN-ILKVEYSLLIYVSVPGSK-------------------KVILDLPLVIGSR--SGLSSRTSSMASRTSSEMSWID----------------------------------------------------------------LNIPDTPEAPPCYMDIIPEDHRLESPTTP--LLDDVDDSQD-----------------------------------------SPIFMYAPEFQFMP-------------------------------------PPTYTEVDPCVLNNNNNNNNVQ----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M7W1-1", "uniprot_id": "TXNIP_RAT", "id": "Q5M7W1-1", "name": "Thioredoxin-interacting protein", "aln": "-----------------------MVMFKKIKSFEVVFND----PEKVYGSGEKVAGRVTVEVCEVTRVKAVRILACGVAKVLWMQG------------------SQQCKQTLDYLRYEDTLLLEDQPT-GENE----------------------------------------------------MVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGCVDYWVKAFLDRP-SQPTQ------------------------EAKKNFEVMDLVDVN--TPDLMAPVSAKKEKKVSCMFIP--DGRVSVSARIDRKG----------------------------------------------------------------------------FCEGD----------------------DISIHADFENTC-SRIVVPKAAIVARHTYLANGQTKV-------------LTQKLSSVRGNHIISGTCASWR--GKSLRVQKIRPSILGCN-ILRVEYSLLIYVSVPGSK-------------------KVILDLPLVIGSR--SGLSSRTSSMASRTSSEMSWID----------------------------------------------------------------LNIPDTPEAPPCYMDVIPEDHRLESPTTP--LLDDVDDSQD-----------------------------------------SPIFMYAPEFQFMP-------------------------------------PPTYTEVDPCVLNNNNNN--VQ----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H3M7-1", "uniprot_id": "TXNIP_HUMAN", "id": "Q9H3M7-1", "name": "Thioredoxin-interacting protein", "aln": "-----------------------MVMFKKIKSFEVVFND----PEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQG------------------SQQCKQTSEYLRYEDTLLLEDQPT-GENE----------------------------------------------------MVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGCVDYWVKAFLDRP-SQPTQ------------------------ETKKNFEVVDLVDVN--TPDLMAPVSAKKEKKVSCMFIP--DGRVSVSARIDRKG----------------------------------------------------------------------------FCEGD----------------------EISIHADFENTC-SRIVVPKAAIVARHTYLANGQTKV-------------LTQKLSSVRGNHIISGTCASWR--GKSLRVQKIRPSILGCN-ILRVEYSLLIYVSVPGSK-------------------KVILDLPLVIGSR--SGLSSRTSSMASRTSSEMSWVD----------------------------------------------------------------LNIPDTPEAPPCYMDVIPEDHRLESPTTP--LLDDMDGSQD-----------------------------------------SPIFMYAPEFKFMP-------------------------------------PPTYTEVDPCILNNNVQ---------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99KN1-1", "uniprot_id": "ARRD1_MOUSE", "id": "Q99KN1-1", "name": "Arrestin domain-containing protein 1", "aln": "--------------------------MGRVQLFEIRLSQ----GRVVYGPGEPLAGTVHLRLGAPLPFRAIRVTCMGSCGVSTKAN------------------DGAWVVEESYFNSSLSLADK---------------------------------------------------------------GSLPAGEHNFPFQFLLPAT-APTSFEGPFGKIVHQVRASIDTPRFSKDH------------------------KCSLVFYILSPLNLNS-IPDIEQPNVASTTKKFSYKLVK--TGNVVLTASTDLRG----------------------------------------------------------------------------YVVGQ----------------------VLRLQADIENQS-GKDTSPVVASLLQKVSYKAKRWIY-------------DVRTIAEVEGTGVKAWRRAQWQ--EQILVPALPQSALPGCS-LIHIDYYLQVSMKAP----------------------EATVTLPLFVGNIAVNQTPLSPCP---GRESSPG-------------------------------------------------------------------TLSLVVPSAPPQE--EAEAVASGPHFSDPVSLSTKSHSQQQPLSAPLGSVSVT----TTEPWVQVGSPARHSLHP-PLCISIGATVPYFAEGSAGP-------------------------------------VPTTSALILPPEYSSWGYPYEAPPSYEQSCGAAGTDLGLIPGS-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0BNL6-1", "uniprot_id": "ARRD1_RAT", "id": "B0BNL6-1", "name": "Arrestin domain-containing protein 1", "aln": "--------------------------MGRVQLFEIRLSQ----GRVVYSPGEPLAGAVHLRLGAPLPFRAIRVTCMGSCGVSNKAN------------------DGAWVVEESYFNSSLSLADK---------------------------------------------------------------GSLPPGEHNFPFQFLLPAT-APTSFEGPFGKIVHQVRASIDTPRFSKDH------------------------KCSLVFYILSPLNLNS-IPDIEQPNVASTTKKFSYKLVK--TGSVVLTASTDLRG----------------------------------------------------------------------------YVVGQ----------------------VLRLQADIENQS-GKDTSPVVASLLQKVSYKAKRWIY-------------DVRTIAEVEGTGVKAWRHAQWQ--EQILVPALPQSALPGCS-LIHIDYYLQVSMKAP----------------------EATVTLPLFVGNIAVNQTPLSPCP---GPGSSPG-------------------------------------------------------------------LLSPVVPSAPPQE--EAEAVASGPHFSDPVSLSTKSHSQQQPLSTTLGSVSVT----TIEPCVQVGSPARHSLHP-PLCISIGATVPYFAEGSGGP-------------------------------------VPTTSALILPPEYSSWGYPYEAPPSYEQSCGAGGTDVGLIPGS-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N5I2-1", "uniprot_id": "ARRD1_HUMAN", "id": "Q8N5I2-1", "name": "Arrestin domain-containing protein 1", "aln": "--------------------------MGRVQLFEISLSH----GRVVYSPGEPLAGTVRVRLGAPLPFRAIRVTCIGSCGVSNKAN------------------DTAWVVEEGYFNSSLSLADK---------------------------------------------------------------GSLPAGEHSFPFQFLLPAT-APTSFEGPFGKIVHQVRAAIHTPRFSKDH------------------------KCSLVFYILSPLNLNS-IPDIEQPNVASATKKFSYKLVK--TGSVVLTASTDLRG----------------------------------------------------------------------------YVVGQ----------------------ALQLHADVENQS-GKDTSPVVASLLQKVSYKAKRWIH-------------DVRTIAEVEGAGVKAWRRAQWH--EQILVPALPQSALPGCS-LIHIDYYLQVSLKAP----------------------EATVTLPVFIGNIAVNHAPVSPRP---GLGLPPG-------------------------------------------------------------------APPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLATLSSVPG-----APEPCPQDGSPASHPLHP-PLCISTGATVPYFAEGSGGP-------------------------------------VPTTSTLILPPEYSSWGYPYEAPPSYEQSCG--GVEPSLTPES-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A7Q5-1", "uniprot_id": "A0AB13A7Q5_DANRE", "id": "A0AB13A7Q5-1", "name": "", "aln": "--------------------------MGKVQEFEITFTN----NKVVYNPGESISGTVRIKSSHSLQFKAIKVCCVGSCGISSKLN------------------DASWMLEEKYLSSTLSVADK---------------------------------------------------------------GTLPPGEHSFPFQFLIPAS-VPTSFEGPFGKILYKIRAFIDTPRFSKDY------------------------KAQRPFYLLNVLNLNE-LPDIEQPSCAVTTKKFNYLLVK--TGTLMLKAYTDLRG----------------------------------------------------------------------------YTPGQ----------------------VIKLSAEIHNKS-GKDTGYVMASLIQRVSYKTKRPVF-------------DLRPIAEVEGAGVKAGKHAEWR--EQIIVPPLPQSGLTGCN-LIDIEYFIQVSLKSP----------------------EAAVTLPIYIGNIAVNLTPSIPHPMAHGVPMPTGPSL----------------------------------------------------------------NPAAVVPSAPPVEEELAGQLAAGG--GDSEEIPTKSHSQQDPSGAPLSVAPYGHASGPVLPQSQQHVQSTDGSAP-LFCLSTGATIPFFTDGNATP-------------------------------------VPTSCPLILPPEYSTWEYPHEPPPTYEESCSSNNSSFNSSMR--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TT80-1", "uniprot_id": "A0AB32TT80_DANRE", "id": "A0AB32TT80-1", "name": "", "aln": "--------------------------MGKLQEFEISFDN----NKTVYSPGESLTGTLKISIAQSIQCKAIKVNCQGFCGVTSKSN------------------DTDWTDEEQYFSSSVSIADK---------------------------------------------------------------GTLKEGEHSFPFKFLLPAA-APTSFVGPYGQIMYRVRAFIDTPRFAKDY------------------------KIEKPFSMTNTLNLNE-VPGIREPSSSSVTKNFSYMLVK--NGTVVLNAKTDMRG----------------------------------------------------------------------------YIAGQ----------------------IIKVSAGIENKS-DKTTGHVVASLMQKVTYNTKKQTY-------------DLRSVAEVEGPGVKGGNKSEWN--QQIIVPALPHSSLSDGN-LIQICYYIQVYLKYP----------------------EVALTLPICIGSVALDPSQPSHSQT--VAPMPAPR------------------------------------------------------------------ITPAPSPSAPESEASNLPPRPAPKPAPKPRPRSTHASPSAPPVDLYPQLPSVSNYNGEMLKSPHQEPGSQGPVSPNAFSYAPGLSFRQRQSSSGPS-------------------------------------APPLSLSSSSQDRNQMPSSASVPPSYRSSAYPQATNSEVLDESSSKNW--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7K8-1", "uniprot_id": "Q9I7K8_DROME", "id": "Q9I7K8-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "-----------------------------MVICEIEFCN---NSQGIFYAGQLISGQVVIKTEKEKSVKAVILNIKGYAETHWADTEHD---------PDDQSNGESFNGHVDYLATRAYLHGS------SSS----------------------------------------------------IEVLIEPGTSSYRFACQLPIT-CPSSFEGTLGRIRYLVNVRFVRP-WKFDL------------------------NFNRCFTVIKVMDLNSESLMLRVPSQVESQRTFCCFPCR--SSPLSMRLSVPQSG----------------------------------------------------------------------------FVPGQ----------------------IVPVEVMVSNDS-GVAVEDITVKLTMVVIYYSQPPSA-----DTN----KDRFEMVLKTGGGVSTKCRQQFT--FDLKVPPTPPTCFNLCS-IIQIGYQVEAEARVKGCHG------------------GQSLHMPITIGSVPLT-KQLQKE--PRTWGEVLPPQQL-------------------------------------------------------------DAKALILIGSEQNGEALGSPNPWAADPSIAPPSYAEAKHISPD-----------------------------------------PHKFSKSKKKSQKRGVKGSQERKAE----------------------TIVFSPLYAVFDLSNQVDEMTLRANEPKTDG-----GYVNEGVEKSTWL-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JQV1-1", "uniprot_id": "A8JQV1_DROME", "id": "A8JQV1-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "----------------------------MGIICQILFHN---NTQGVFYAGQMVAGQVTLSTDKAIQIKAIRLKLKGYAETHWTESKTD---------SNNKSTSESYNGFEKYLSSKVYLLGS------EIS----------------------------------------------------PEMALEPGTRSYNFACPIPIN-CPSSFEGTHGRIRYMVDVNIIQP-WKYDS------------------------IFSRAFTVIQVMDINTYNSVSQVPVQAKTEKTFGVWPFR--SDPLTLELNLPQTG----------------------------------------------------------------------------FVPGQ----------------------TVPANVLIGNES-KIRVHEVKVGLSMMITYYSDLSSG-----SKC----ERKSVAKLKADG-VLRNSRKMYD--FQLMIPSTPPSCFHLCR-IIKIGYQIEVVAKVKGMHI------------------NGTLIMPVTICGVPISPSAVQYT--PQSSGPEAPEQ-----------------------------------------------------------------RALTLIEGEGAFAPAAPPYPWSEGSTLSPPNYAEAMHSHSD-----------------------------------------SEKQSESGNAQEKS------------------------------------YKPLYPVFDLSTSTVEKSKEAALDKEE-------------KK---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7L0-1", "uniprot_id": "Q9I7L0_DROME", "id": "Q9I7L0-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "----------------------------MTVTCEIDFDN---NPHGTYFGGEVLTGRVTLKLDKMKLVKAITLNITGYAETRWIERVT----------TNRRRRRRTFCGREDYIASKTFLVGS------NLS----------------------------------------------------SQVSIEAGIHTYNFVCLIPTE-CPSSFEGSHGRVRYMATVTLVRP-WKFDQ------------------------SYTRCFTVLKVMDLNFDSPLLRVPAHSETSKTYCCWPCR--SDPLALQLTVPQTG----------------------------------------------------------------------------FVPGQ----------------------NVPLSVLVTNDS-HIPVEQLLISFVMLVTYHSKPPSMP----NTT----SERLVVNTFKGDAVQRNCKKLFS--YEIRVPATPPTCFNLCG-IIQIAYQVEVEARVKGCHN------------------NEVVTIPLTIGSVPLA-QHVPIQ--PRGFVPQLNVN---------------------------------------------------------------------ELAVEEVATAPNSSSPWSVDASIPPPNYQEAVHMRST-----------------------------------------AATRSDDLDDPEPVPPN---TLSLD----------------------GGAYKPLYPVFDIPSPSAPPPTDYTQNYMAERAFVNPAMDVDKDKGTWL-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7L1-1", "uniprot_id": "Q9I7L1_DROME", "id": "Q9I7L1-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "----------------------------MVVTCEISFDN---NKHGTFYAGQLVKGCATLKCDRSKEVQAVLLKVVGYSITKWSEKSLG---------STKL-----YVGREDYLSSNTYLVGSEQNNTHNNT----------------------------------------------------HRLTIEAGVHSYNFTCQLPYQ-CPSSFEGRHGCIRYIVKVLLIRP-WKFDQ------------------------AYTKGFTVLKMLDLNFDTPQLKSAAHSEGYRTFCCGPCK--TDPLKLELHLPQAG----------------------------------------------------------------------------YVPGQ----------------------KIPVTIVVVNNT-AVAVSEIRLSLVMLVRYYSVSPEH------SR----VERLIISRAKGESVLKQCTRSQT--IDLPVPSTPPTCVELSN-LIQIAYQLEVEALVKSLRE------------------QQLMVMPVTVGTIPLAVSGIVVQQPPRRSAHYEGPDS--------------------------------------------------------------RRNPPDELPMVTALESLPSDLASSAADSALP-NYEESRHTQRG-----------------------------------------NINEEELHAFGSNE------------------------------------FAPLYPVYSIPSPTPVLTANARNAGFVN---------QSFVK---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VI00-1", "uniprot_id": "Q9VI00_DROME", "id": "Q9VI00-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "----------------------------MPSSCSFELDR----REPIYYSGETVNGRAILTTTSEKSVNEVYILFEGEAKVRWDERRTRTRG------GKTEHYTEYFRGKQQYLYTRTSVFGS---------------------------------------------------------------GNLPPGTHTYNFCIPLPLE-CPSSVVAQYGKIFYEVSVVIDRQ-WRFNN------------------------VFKQPLTVIQTYNLN-MSPQLLMPLVREDIKHFCCWPCS--SGPVLSTLTIPFGG----------------------------------------------------------------------------YAPGQ----------------------KIRFTLEIDNQSSGYDLNGIELKLKQIYKFQAQTPHHK----TRE----KEHSLNKSCQQERVLRLSKKKIE--GTLAIPAVPPSSRTEG--IISVSYQVILTISTGDCHV------------------DSDFEVPIVIGTIPLIQS------------------------------------------------------------------------------AENPASAAQWIPETPDTPAGAAADLPPSYDKCKPPTFEEATNFGERFIDIDQDEHNRTD--------------------------DFIPRYPMYTNFAMPSAPP----------------------------------QPPEEFATNQPVPVLSLPHDPTAPLVGQNNTDRPTQSYGWNTNS------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VHZ9-1", "uniprot_id": "Q9VHZ9_DROME", "id": "Q9VHZ9-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "----------------------------MPTTCVFQLDR----LNPVYNSGEYISGRILLRTDKVKRVNAVYVTLEGEAKVQWSMS------------GKSE--TANYSGHQQYLHSRTNVFDN---------------------------------------------------------------TLFRAGVHVYVLTLRIPPD-CPSTCKGPYGYIAYTISLTIDKP-WGFDE------------------------VFRKPIIVVQTLDLN-YNAEFSLPVKDENLKYLCHWPCI--SGPICSTLTLPASG----------------------------------------------------------------------------FTPLQ----------------------EVPYRLEVDNQSPHYDIIGVEVSIKQHFVFLSRKPVKR----N-F----YSKTLVKELISDRTLRLSKRQYE--SSICVPMDTPRSTLNPNYIVFLHYTLQVKLKTGYFHY------------------DTDLSVPIIVGTTSLQHLRDSVHTQQPVRRTPTPERQRLIERVTPRPP------------------------------------------------TVEEDSAGEADPATDEPHRVIEDDEPPSYDSCLPPSFSFATLAGSQQTLGSNAAVVLQR--------------------------IHLPKFPGFSTLIGTAPAHGMEDSGLD----------------------MHMYRSYGSLNTDHTGRSLDTFGSLCGPLSEHVEEQEQEAEENLDVTAQVHRPIQRATVSEVENVLQDEHLF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VI53-1", "uniprot_id": "Q9VI53_DROME", "id": "Q9VI53-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "---------------------------MGLKGCELQLDN----PWNTYYAGQTVNGQVKFTFDSPKKVRGIIIRFLGEANTEWSEEKSVTTSE-----GKTENEVTQLKGHEEYFKIQYYLLGGKNSS----------------------------------------------------------ETELPPGTHTYPFTCALPPN-LPSSFEGEFGHVRYTIKVTLDRP-WKFDQ------------------------DMKMAFTVIAPVDLN-LNPRVKEPFKLELEKSFCCFCCR--SGPLAVITNIPQTG----------------------------------------------------------------------------FVSGQ----------------------VLPITCEVDNTS-NVNLTAVKFELRKLVTFHTNQPRS-----EKR----ESKVIIANLSVGPVNGGESRTFT--QQMEIPALPPTNLLNCG-IIALDYDLHVECEVSGPHR------------------NLTGKVPITLGTIPLAGVRPPTQFTDAPSAVQSEDPS-----------------------------------------------------------------LAPTQPVSPASPPGGDGVGGALGWNVADSTGGGSLYPNIP--------------------------------------------PPQFVETQYR--------------------------------------APTIAGRDDSEHTQMIGDGAFAPRYPTFQFNNATAPPASQ----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KGD9-1", "uniprot_id": "A0A0B4KGD9_DROME", "id": "A0A0B4KGD9-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "----------------------------MPIECLISFDN---NPQGVYYAGQELSGVVDLSVDATKRIKGIHVTVSGYAKIRWIKKGYPR-----------DSERAMCRAYRSYLSSRSYVLGSCANN---------------------------------------------------------SSIDWPAGEYSYTFHVILPDN-LPTSFDGKYGQIHYEIITTIERA-ARHPK------------------------VFKLPFTVIQPLDLN-ADAIYRVPLEILDRKRFWSFCCP--TGPLTVKFSTPYCG----------------------------------------------------------------------------YAPGQ----------------------KIHFVLYINNES-SIDIIECEVKLKQEVSYESHDPQHE----YR-----YDKHLIARKQFGNVLRWSRKVYR--GYLDLPSIPPTSVKPTC-PISVNYSIKIIVNPTEFHW------------------KLKLKIPLTIGSIPIMDGPEALLRFNRQQQQHQVVSQNLQMSTQQRQRDRDRDRDMNVDRERDRDRDRDRISASVQQRRISSINNNNNNHGRLVGGLLPTNSNMNMITNVSPTPTSSTPSSTPTTAALRPTAMPAILVTSDSDNPPDYIPMMPPSYEDAMALSEKFSDDTEFLTN-----VSMSSILSAQADVTTSEPFKPR--------------------------------YPVYYDYETPTIPPETLYDESSSRLRLTLSCQDSAAPETDEDLAPNTRGGEPPSCEKK----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E8K8-1", "uniprot_id": "Q0E8K8_DROME", "id": "Q0E8K8-1", "name": "", "aln": "-------------------------MPRKLLKFLIIFDN----TSLLYFPGQFLSGRVLIELQDETPALGLHFHVVGEGVVRNGRR------------------QERTYDKENYIDFRMRLLGDVDQG---------------------------------------------------------GPAILSPGIHSFPFKLGLPLG-LPSTFLGRYGWIQFYCKAALREN-NGIIH------------------------KNHQVFIVMNPIDLNLEKPILAQPFTCEVEHKLGVVCVG--GGQIKCRVSLDRGG----------------------------------------------------------------------------YVPGE----------------------NILVTAFISNYS-NVSIKRTKASLTETIEYLARGKVVQ----T-------EKRELAVLVRGKIRPGAKDEWH--NELYVPPLPPTNLHGCH-LIKISYDVFFVIEPKSMEK------------------EIKLQLPIVLATYPFRHSGDAVN---------------------------------------------------------------------------------ANTWPESVLKPDTHTHYPSTLPIFRPWLHEKPIEA-------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGU7-1", "uniprot_id": "Q9VGU7_DROME", "id": "Q9VGU7-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "----------------------------MSSKVNFVFDS---NPLGLYQAGQLISGTAELITERPKTIRSIFITINGYGETRWQESEERVGED-----GKTTKSLVTHTTTEVYYSTDQPVYGQAGGS----------------------------------------------------------QLELPTGKYVFPFRATIPPN-APTSFNGAHGQIKHEVTLTIDRA-VRYNN------------------------TFKQCFTVILPHDLN-RRLEYKEPLQRLESKSFWWGSIFGAHKPMIMDVSTSYSA----------------------------------------------------------------------------YVPGQ----------------------KIHFHLVLDNQS-DVQCMDVKVRLIKNVSYRANSSGAK----EQLK---VTESRVADKHCGEVLKHNKAKFD--EFLTVPPTTPSTQSEKD-PIRVSYTLRFIAKTFKLHGG----------------GDLVMDFPITIGTVPLLGSADDKGPGAEKSQPSGASHP------------------------------------------------------------------GSPNFQEDVSDEQFESNTFKPRYPVYPFDGKPGTNGSNGAAN-------------------------------------FPSLYPKAEEAHPATPVKFTPNPVSP----------------------AAQKSPPYTTNTPVASPPGGNFEVLGFSIPPDYKPTPSAPAASSTGGIGWK---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1NYX2-1", "uniprot_id": "A0A8M1NYX2_DANRE", "id": "A0A8M1NYX2-1", "name": "", "aln": "-------------------------MQRSIKELSVRYDP--INETNTFTNGDIVEGRVVLEVTKEINVENLFVKLTGDADVRWTEGSGDD--------ERSYSDHERYFKQKQYFIQDSSKKGQCEKNTTLVSG-------------------------------------------------ETYGSVIKPGSHVFPFRFQLPQQNMPPTFKGFHGWVKYIVMVKLKRSWKPTSS------------------------AQAEINFAPRNFGTN---DHLLQPQSGTEDKKMKLFGSG----KMSMTVTTDKTG----------------------------------------------------------------------------YMLGE----------------------IIRVSVDIDNSS--SRDIKLKYSLKQLQTFIAGRSTT------------HAHKDIVKETKDCIPSGGKTRFV--VDIKLPHDIMVTIENCR-IIKVQYELKVYLDVSFAS-------------------DPTVKFPVVIIPPLQQCPPWHDPPPPYMPPQP------------------------------------------------------------------------NLVPYPGGAAPPPAGLYPNLYDPVPPYPGTAAGTFPNP-----------------------------------------NAMLPGFHP------------------------------------------APSAPVYDLNQSTKESFPNAPH----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGU4-1", "uniprot_id": "Q9VGU4_DROME", "id": "Q9VGU4-1", "name": "", "aln": "---------------------------MESERLRITLDS----ADRVYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEILRKNSN------NNEYSRSLFYTSKEVYEHSETPLPDFEPRG-----------------------------------------------------------LELSAGEHTFIFEVALGRQ-LPSSFKGSYGAIKYKMRVLIQRP-WTFDE------------------------RHTIPFTVVKNMPLQPMQRSIPSSLEKQVTKTISLFGTR----PITLLALLPEDF----------------------------------------------------------------------------AVRGE----------------------PLRICATVINNS-TTAVEKLRFTVLQYVTYYSHVPLR------VQK---VECIAVATKETGSVQKKTERSFA--HELLLPDGAQPTDEQMSGVITIVYELRVEAVLRGFFK------------------NLILNLPFKVYSQDPSNRQSSLRPPPPPRPNDGPPGPELGSGNLFEPALPVYPSLDSSIGSPS--------------------------------HSSQFSECSSINSITSDSSAATLSPAVGAGTGGMDMSYTSGSQSSQYGSPSARTSLRSSNVPYMPYSSSPLMVQSYPPPHLPAYPPPESPQYSLLALTPPPAGVVAAPPTGGA----------------------AAGGAPAYSQLPSTSASASFLQPRQAPGAHELPPSYEELFGLANAPPGTPK---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7K7-1", "uniprot_id": "Q9I7K7_DROME", "id": "Q9I7K7-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "----------------------------MSHRCEIQLDN----PRGVYRAGDTVNGHVYLTLSERALIKAICLEANGYASTAWQQPQKHKNQKK--NEQPVVVQSLDFDYRVDYFAKIDYFVGSEAAQP----------------------------------------------------------QIMEAGTYNYGFHVKLPKN-CPGNFEGGHGHIRYTLQVLIHSSADRPLE------------------------VLHVRQLQIFPQNSLSQETRSCEIQIYEQTPRLRFWMKP-----LHLQLQIPRQG----------------------------------------------------------------------------YSPGA----------------------GISVHLKLHNPE-KLTLREAVYSLVQISTYVAHLKNKPKRLETKVE---RQTVLSSRHELHNLPRGELQNFQHLHMLQVPQTAATLTVAGCACLQLNYEVEVLVTTQQEKR------------------LIAARMPVIIGNVTPPCPGKLLMQEPIDGTAPEPTPP---------------------------------------------------------------------VETASTLIPNFSISTTSLASNFREAEFMVATNLNKT-----------------------------------------NKHYLSGEQLDFRP---------------------------------------RYVYYEMDQTQSEEVKSH------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12502-1", "uniprot_id": "LDB19_YEAST", "id": "Q12502-1", "name": "Protein LDB19", "aln": "MAFSRLTSTHQSNHNGYSNSNKKGQSLPLTLSIDVESPPCVLYGSAMESSGAVLSGLFTVTVVDPYSSAEDKSLKNTESNVSTTSKSLKRKSTFGSALSSRLSSLSASTSNISPSTSSTSISHSPTPANLRIMAGYTKITITSVTLSLVQKIHFHKPFVPNISSMQTCMNCKTKITNMKSWEIQSNTQDLSVGSHSYPFSYLIPGSVPCSSSLGATAETQVKYELIAVVTYIDPHRNSFSSGHSTPRKEGSSSKKRLLQLAMPIAVTRSIPRGPDKNSLRVFPPTELTAAAVLPNVVYPKSTFPLEMKLDGVSSGDRRWRMRKLSWRIEETTRVKAHACPVHKHELRQLEEQVKIKESEKSKKPRSHIKRYGELGPQIRVAVNSLENMPSQRLPGEPGREQAPNSSGPASTGNVGLDDENPVNEDEEDQPGSEFIHPSDDALRQELLMQQQRARQQQLQQELKNNSSLFTEEVRIISKGEMKSGWKTDFDNNGKIELVTEIDCMGLNSGVSNPVMHASTLQTPSTGNKKPSINVACDIQDPNLGLYVSHILAVEIVVAEETLQYANGQPIRKPNSKNKKETNNNTMNVHNPDQRLAELSPIFANRN-----------------------------TPKVRRMGPEDITPVNSNKSNHSTNKEKASNGASNSNIVSVPTGAARVLRMQFRLTVTERSGLGISWDEEVPPIYQDVELLSPPCYELSINNGIKNKLYSTMSTPVRSEDDFVGGSDEDIGNYESQGLEPGPNVQEVTITQNKLTIPPTAHHYQPASSSQRSLTTVQSPPLESVVSVQGSVPFRGHVLTPHSTRDIRIQNFSDFLDSNRITQ--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : * . . : : : . . . : : : : . . : ", "identical_positions": 2, "similar_positions": 17, "identity": "0.24%" }, { "cls_id": "homologset.agr.SGD:S000005850", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AAN3-1", "uniprot_id": "A0A8I6AAN3_RAT", "id": "A0A8I6AAN3-1", "name": "Delta-1-pyrroline-5-carboxylate synthase", "aln": "-MLRHVQRSGLQPFSQRLLPWVQSIALPRSHRVQPSAIRHVRSWSNIPFITVPLSRAHGKPFAHRSELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSVLQNQGREMMLVTSGAVAFGKQRLRHEILLSQSVRQALHSGQNHLKEMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIVNTNDAVVPPAEPNSDLQGV---NVISVKDNDSLAARLAVEMKTDLLIVLSDVEGLFDSPPGSDDAKLIDIFYPGDQQSVTFGTKSRVGLGGMEAKVKAALWALQGGTSVVIANGTHPKVSGHVITDIVEGKKVGTFFSEVKPAG--PTVEQQGEMARSGGRMLATLEPEQRAEIINHLADLLTDQREEILLANKKDLEEAE--GRLAGPLLKRLSLSTS-KLNSLAIGLRQIAASSQESVGRVLRRTRIAKNLELEQVTVPIGVLLVIFESRPDCLPQVAALAIASGNGLLLKGGKEAMHSNRILHLLTQEALSIHGVKE-----AIQLVNTREEVEDLCRLDKIIDLIIPRGSSQLVRDIQKAAKGIPVMGHSEGICHMYVDSEASVDKVTRLVRDSKCEYPAACNALETLLIHR------DLLRTPLFDQIIDMLRVEQVKIHAGPKFASY---------LTFSPSEVKSLRTEYGDLEVCIEVVDSVQEAIDHIHKYGSSHTDVIVTENEKTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGLEGLLTTKWLLRGQDHVVSDFS-EHGRLKYLHENLPVPQ-----RHFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z110-1", "uniprot_id": "P5CS_MOUSE", "id": "Q9Z110-1", "name": "Delta-1-pyrroline-5-carboxylate synthase", "aln": "-MLRHMHRSGVQPFRQRLLPWVQSIAVPRSNRVQPSAIRHVRSWSNIPFITVPLSRAHGKPFAHRSELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSVLQNQGREMMLVTSGAVAFGKQRLRHEILLSQSVRQALHSGQNHLKEMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIVNTNDAVVPPAEPNSDLQGV---NVISVKDNDSLAARLAVEMKTDLLIVLSDVEGLFDSPPGSDDAKLIDIFYPGDQQSVTFGTKSRVGLGGMEAKVKAALWALQGGTSVVIANGTHPKVSGHVITDIVEGKKVGTFFSEVKPAG--PTVEQQGEMARSGGRMLATLEPEQRAEIINHLADLLTDQREEILLANKKDLEEAE--GRLASPLLKRLSLSTS-KLNSLAIGLRQIAASSQESVGRVLRRTRIAKNLELEQVTVPIGVLLVIFESRPDCLPQVAALAIASGNGLLLKGGKEAAHSNRILHLLTQEALSIHGVKE-----AIQLVNTREEVEDLCRLDKIIDLIIPRGSSQLVRDIQKAAKGIPVMGHSEGICHMYVDSEASVDKVTRLVRDSKCEYPAACNALETLLIHR------DLLRTPLFDQIIDMLRVEQVKIHAGPKFASY---------LTFSPSEVKSLRTEYGDLEVCIEVVDSVQEAIDHIHKYGSSHTDVIVTENEKTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGLEGLLTTKWLLRGQDHVVSDFS-EHGSLKYLHENLPVPQ-----RNFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54886-1", "uniprot_id": "P5CS_HUMAN", "id": "P54886-1", "name": "Delta-1-pyrroline-5-carboxylate synthase", "aln": "-MLSQVYRCGFQPFNQHLLPWVKCTTVFRSHCIQPSVIRHVRSWSNIPFITVPLSRTHGKSFAHRSELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSVLQNQGREMMLVTSGAVAFGKQRLRHEILLSQSVRQALHSGQNQLKEMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIVNTNDAVVPPAEPNSDLQGV---NVISVKDNDSLAARLAVEMKTDLLIVLSDVEGLFDSPPGSDDAKLIDIFYPGDQQSVTFGTKSRVGMGGMEAKVKAALWALQGGTSVVIANGTHPKVSGHVITDIVEGKKVGTFFSEVKPAG--PTVEQQGEMARSGGRMLATLEPEQRAEIIHHLADLLTDQRDEILLANKKDLEEAE--GRLAAPLLKRLSLSTS-KLNSLAIGLRQIAASSQDSVGRVLRRTRIAKNLELEQVTVPIGVLLVIFESRPDCLPQVAALAIASGNGLLLKGGKEAAHSNRILHLLTQEALSIHGVKE-----AVQLVNTREEVEDLCRLDKMIDLIIPRGSSQLVRDIQKAAKGIPVMGHSEGICHMYVDSEASVDKVTRLVRDSKCEYPAACNALETLLIHR------DLLRTPLFDQIIDMLRVEQVKIHAGPKFASY---------LTFSPSEVKSLRTEYGDLELCIEVVDNVQDAIDHIHKYGSSHTDVIVTEDENTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGLEGLLTTKWLLRGKDHVVSDFS-EHGSLKYLHENLPIPQ-----RNTN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U570-1", "uniprot_id": "A0AB32U570_DANRE", "id": "A0AB32U570-1", "name": "Delta-1-pyrroline-5-carboxylate synthase", "aln": "MSLQRMFSC------SRLLARPNALQTFRRAASQG---------------KMPLARAHGKSFAHRSELRQAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVAMLQNQGREMMIVTSGAVAFGKQRLRHEILLSQSVRQALHSGQNQLKDMSLPVLEARACAAAGQSGLMALYEAMFTQYSTCTAQILVTNLDFHDEQKRRNLNSTLYELLRMNIVPIINTNDAVVPPPEPNSDLQG-----VISIKDNDSLAARLAVEMRADLLIALSDVEGLYDSPPGSDDAKLLDTFYPGDQQSITYGTKSRVGIGGMEAKVKAALWALQGGTSVVIANGTHPKVTGHVITDIVEGKKVGTFFSEVKPAG--PTVEQQTEMARSAGRTLASLEPEQRSDIICALADLLTERKEEILSANKKDMENAVNTGRLSPAMLKRLSLSSS-KLNSLSIGLRQIAVSSQDSVGRVLRRTRVANNLELEQITVPIGVLLVIFESRPDCLPQVSALAIASGNALLLKGGKEAANTNRILHELAQEALSIHGVKD-----AIQLVSTREEVEDLCRLEKMIDLIIPRGSSQLVRDIQRAAKGIPVLGHSEGICHVYVDHEASIDKAIKIIRDSKCDYPAACNAMETLLVHR------DLLRTPVFDQIIDMLRTEQVKIHAGPKFASY---------LTFSPSEVKSLRTEYGDLECCIEVVDSMQEAIDHIHKYGSSHTDVIVTENENTAEQFLQQLDSACVFWNASSRFADGYRFGLGAEVGISTARIHARGPVGLEGLLTTKWVLRGEGHTVADFS-EHGSMTYLHENLPVAQLLPGYRTTS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VNW6-1", "uniprot_id": "Q9VNW6_DROME", "id": "Q9VNW6-1", "name": "Delta-1-pyrroline-5-carboxylate synthase", "aln": "-MLQNSFKLAQS---LRNGFYRNAWRAFSSHGPRQPLVSP----------ERRLEKAH-PTFTERSQLKYARRLVVKLGSAVITREDNHGLALGRLASIVEQVAECHLEGREVMMVTSGAVAFGKQKLAQELLMSLSMRETLNPKDS--KEFDGATLEPRAAAAVGQSGLMSLYDAMFAQYGVKIAQVLVTKPDFYNEETRNNLFCTLSELISLNIVPIINTNDAVSPPMFIRDDEPAGGARRGIPIKDNDSLSAMLAAEVQADLLILMSDVDGIYNKPPWEDGAKLMHTYTSDDSNSIEFGKKSKVGTGGMDSKVKAATWALDRGVSVVICNGMQEKA----IKTIIGGRKVGTFFTEATESANAVPVEVMAENARTGSRQMQALTPAQRASAVNTLADLLVSREKFILDANAKDLAEAQK-SGLAKPLLSRLSLNPA-KLKNLSVGLKQIAEDSHKNVGRVLRRTRLADQLELKQVTVPIGVLLVIFESRPDSLPQVAALAMASANGLLLKGGKEAAHSNKALMELVKEALATVGAEH-----AVSLVSTREEISDLLSMENHIDLIIPRGSSDLVRSIQQQSLHIPVLGHAEGVCHVYIDRDADLEKALRIARDAKCDYPAACNAMETLLIHE------DLMSGAIFGDVCNMLKREGVKIYAGPRLNQQ---------LTFGPPAAKSLKHEYGALECCIEVVPSLDEAINHIHTYGSSHTDVIVTENDAAARQFLGSVDSACVFHNASSRFADGFRFGLGAEVGISTARIHARGPVGVEGLLTTKWILEGQDHAAADFA-EGGGRTWLHETLPLD----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54885-1", "uniprot_id": "PROA_YEAST", "id": "P54885-1", "name": "Gamma-glutamyl phosphate reductase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSS---------QQIAKNARKAGNILKTISNEGRSDILYKIHDALKANAHAIEEANKIDLAVAK-ETGLADSLLKRLDLFKGDKFEVMLQGIKDVAELEDP-VGKVKMARELDDGLTLYQVTAPVGVLLVIFESRPEVIANITALSIKSGNAAILKGGKESVNTFREMAKIVNDTIAQFQSETGVPVGSVQLIETRQDVSDLLDQDEYIDLVVPRGSNALVRKIKDTTK-IPVLGHADGICSIYLDEDADLIKAKRISLDAKTNYPAGCNAMETLLINPKFSKWWEVLENLTLEGGVTIHATKDLKTAYFDKLNELGKLTEAIQCKTVDADEEQDFDKEFLSLDLAAKFVTSTESAIQHINTHSSRHTDAIVTENKANAEKFMKGVDSSGVYWNASTRFADGFRYGFGAEVGISTSKIHARGPVGLDGLVSYQYQIRGDGQVASDYLGAGGNKAFVHKDLDIKTVTL------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. : : **.... : :: *:. : : * * . . * ** *: * *: .:*.**.* . *:: : *::::* .. **:* .: . * * *:*.*:***********: :.:::**:: *.*. :******: :: : : :.::::: : ::.*:.**:::.** :: ***::****. ***.*: : ***:**::*:* :*:* :*.: *. :: *:* :***.***:****:: ::: : : : :* :: . *... :.: *: *: . :.* . :.**:**:.:.* ***.****:. *. *: :**: *: ***:**:**:*:*:********::********::**:: :: :.*..:..:*: * ::*: * : ", "identical_positions": 140, "similar_positions": 163, "identity": "16.87%" }, { "cls_id": "homologset.agr.SGD:S000005853", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99104-1", "uniprot_id": "MYO5A_MOUSE", "id": "Q99104-1", "name": "Unconventional myosin-Va", "aln": "--MAASELYTKFARVWIPDPEEVWKSAELLK-DYKPGDKVLLLHLEEGKDLEYRLD----PKTGELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLP-IYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASE--------ANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRY---RIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADSFHYTKQGGSPMIEGVDDAKEMAHTRQACTLLGISESYQMGIFRILAGILHLGNVGFA--------SRDSDSCTIPPKHEPLTIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDHVNQALH---SAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNK--CALFEKPRMSNKAFIIKHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRVPVKPTKGRPGQT------AKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLG----------DRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKRYLCMQRAAITVQRYVRGYQAR---CYAKFLRRTKAATTIQKYWRMYVVRRRYKIRRAATIVIQSYLRGYLTRNRYRKILREYKAVIIQKRVRGWLARTHYKRTMKAIVYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLMEKLTNLEGVYNSETEKLRNDVERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKSIEERADKYKQETDQLVSNLKEENTLLKQEKETLNHRIVEQAKEMTETMERKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMLNVPKPGHKRTDSTHSSNESEYTFS----SEFAETEDIAPRTEEPIEKKVPLDMSLFLKLQKRVTELEQEK-QLMQDELDRKEEQVFRSKAKE-EERPQ--IRGAELEYESLKRQE--LESENKKLKNELNELRKALSEKSAPEVTAPGAP-AYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQK--EAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETN----------------------------------------------RLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLYFEELYADDPKKYQSYRISLYKRMIDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQ--IIDEPIRPVNIPRKEKDFQGMLEYKREDEQKLVKNLILELKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVS--FWLSNT----CRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENILQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIAD------EGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIVGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQMRLRD--------RKDSPQLLMDAKHIFPVTFPFNP-------SSLALETIQIPASLGLG-FIARV------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QYF3-1", "uniprot_id": "MYO5A_RAT", "id": "Q9QYF3-1", "name": "Unconventional myosin-Va", "aln": "--MAASELYTKFARVWIPDPEEVWKSAELLK-DYKPGDKVLLLHLEEGKDLEYRLD----PKTSELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLP-IYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASE--------ANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRY---RIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADSFHYTKQGGSPMIEGVDDAKEMAHTRQACTLLGISESYQMGIFRILAGILHLGNVGFA--------SRDSDSCTIPPKHEPLIIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVGHVNQALH---SAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNK--CALFEKPRMSNKAFIIKHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRVPVKPTKGRPGQT------AKEHKKTVGLQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLG----------DRKQTCQNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKRYLCMQRAAITVQRYVRGYQAR---CYAKFLRRTKAATTIQKYWRMYVVRRKYKIRRAATIVLQSYLRGYLARNRYRKILREHKAVIIQKRVRGWLARTHYKRTMKAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLMEKLTNLEGVYNSETEKLRNDVERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKSIEERADKYKQETEQLVSNLKEENTLLKQEKETLNHLMVEQAKEMTETMERKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMLNVPKPGHKRTDSTHSSNESEYTFS----SEFAETEDIAPRTEEPTEKKVPLDMSLFLKLQKRVTELGQEK-QLMQDELDRKEEQVLRSKAKG-GERPQ--IRGAELGYESLKRQE--LESENKKLKNELNELRKALSEKSAPEVNAPGAP-AYRVLMEQLTAVSEELDVRKEEVLILRSQLVSQK--EAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETN----------------------------------------------RLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNEN-------------------------LDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQ--IIDEPIRPVNIPRKGKDFQGMLEYKREDEQKLVKNLILELKPRGVAVNLISGLPAYILFMCVRHADYLDDDQKVRSLLTSTINSIKKVLKKRGDDFETVS--FWLSNT----CRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENILQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIAD------EGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIVGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQVRLRD--------RKDSPQLLMDAKHIFPVTFPFNP-------SSLALETIQIPASLGLG-FIARV------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y4I1-1", "uniprot_id": "MYO5A_HUMAN", "id": "Q9Y4I1-1", "name": "Unconventional myosin-Va", "aln": "--MAASELYTKFARVWIPDPEEVWKSAELLK-DYKPGDKVLLLHLEEGKDLEYHLD----PKTKELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLP-IYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASE--------ANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRY---RIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFT--------SRDADSCTIPPKHEPLCIFCELMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH---SAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNK--CALFEKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQM------AKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLS----------DRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQAR---CYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFS----SEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEK-QVMQDELDRKEEQVLRSKAKE-EERPQ--IRGAELEYESLKRQE--LESENKKLKNELNELRKALSEKSAPEVTAPGAP-AYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQK--EAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSS-------------------ALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNEN-------------------------LDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQ--IIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVS--FWLSNT----CRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENILQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIAD------EGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIIGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQMRLRD--------RKDSPQLLMDAKHIFPVTFPFNP-------SSLALETIQIPASLGLG-FISRV------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TCA0-1", "uniprot_id": "A0AB32TCA0_DANRE", "id": "A0AB32TCA0-1", "name": "Unconventional myosin-Va", "aln": "MNQELDFMFIKYARVWIPDDEEVWRSAELTK-DYRQGDGVLQLQLEDGKDLEFKLD----PKTNNLPHLRNPDILVGENDLTALSYLHEPAVLHNLKVRFIDSKLIYTYCGIVLVAINPYETLP-IYGADIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASE--------ANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKKY---HIIGANMRTYLLEKSRVVFQADEERNYHIFYQLCASAHLPEFKALKLGKANDFHYTKQGRNPVIDGVDDAKEMSTTRNAFILLGINESYQMGLFQILASILHLGNVDVK--------DRDSDSSIIPPNNGHLSVFCELMGVTYQDMSHWLCHKKLKTATETYIKPIPKLQAINARDALAKHIYAKLFNWIVDHVNKALH---STVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIEAKMGILDLLDEECKMPKGSDDSWAQKLYNTHLKT--CALFEKPRMSNKAFIIQHFADKVEYQCDGFLEKNKDTVNEEQINVLKASKFDLLVELFHDEEKATSPTGAAP-GPGGRTRLSVKPDKGKSSQA------SKEHKKTVGLQFRNSLQLLMETLNATTPHYVRCIKPNDYKHAFTFDPKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLT----------DKKMTCKNVLEKLVQDPDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRCWLARKKYLRMKHAATTIQRFVRGYQAR---CLAKFLRRTRAAIIIQKYQRMYIQKTCYKRKQAAALAMQCILRAYMARQLYKALLREHKAVIIQKMVRGWLARQWFKRSLKAIVYLQCCIRRMRAKRELKKLKIEARSVEHFKKLNIGMENKIMQLQRRIDDQNKENRSMSERLNTLETSHAVESERMRAEVTRLRGAEEDAKNNANKVTSLLEELERLRKDLQNTQKEKKAIEDWAQTYQDEMEKMISELKEQNQLLKTEKNNLNQLIQEQSQQWTDKMQRALKEETQQLENDLNEERSRYQNLLTEHLRLEEKYDDLKEEITLAVNVPKPGHRRTDSTHSSNESECTYN----SEFAESEEGSRVGEDVS--KSILDMSLFLKLQKRVSELEQEK-QSLQNELDRREEQFQRARARDDEEHKK--ARGAELEYESLKRQE--LESENKKLKHDLNQMRQSLRGGAEAGSGAPGSP-AYTVLLDQLNASNEELEVRKEEVLILRSQLVSQK--EAMQ---HKTTMTEPLPYIEDVQKLTDAKEISQAYMGLKDTNRSPRFTRRPTEVNELMSRLRSPFPDYHKLNEDGELWLVYEGLKETNRLLESQLQAQRRSHDNEVEVLRGELHSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNEN---LELHSDDPKEYKAYRISMLRRMVDLMEQLEKQDKTVRKLKKQLKVFAKKINDLEGGQMD-VSPGQ--TADEPVHPVNIPRREKDFQGMLEYKKEDELKLVKNIILELKPRGVAVNLIPGLPAYILFMCLRHADYINDDQKVRSLLTSVINSIKKILKKRGDDFETVS--FWLANT----CRFLHCLKQYSGDEQFMKHNSPKQNEHCLSNFDLAEYRQVLSDLAIQIYQQLIKCMENILQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIAD------EGTYTLDSIIRQLNTFHSIMCHHGTDPELIKQVVKQQFYIIGAVTLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMTCGAKETLEPLIQAAQLLQVKKKTDEDAEAICSMCNALSTAQIVKVLNLYTPVNAFEERVSVLFIRTIQTRLRD--------RKESPQLLMDTKLIYPVTFPFNP-------SSLALETIQIPSSLNLA-FLTRV------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3API9-1", "uniprot_id": "A0A8M3API9_DANRE", "id": "A0A8M3API9-1", "name": "", "aln": "--MAAPELYSKLARVWIPDPAEVWRSAELSR-DYRPGDPVLHLLLEDETELEYKLD----LKSGVLPPLRNPDILVGENDLTALSYLHEPAVLHNLRVRFTDSKLIYTYCGIILVAINPYESLP-IYGSDIINAYSGQNMGDMDPHIFAVSEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVSESSDD--------ASVEEKVLASNPIMEAFGNAKTTRNDNSSRFGKYIEIGFDRKH---HIIGANMRTYLLEKSRVVFQASEERNYHIFYQLCACAHLPEFKPLKLGSADDFPYTNQGGSPVIVGVNDLKEMQATRKAFSLLGITEAHQMGLFQILSAILHLGNVEVK--------ERGSSSCSISDENGHLDMFCDLTEVSNESMAHWLCHKKLKTATETLNKPVTRLEAVNGRDALAKHIYAKLFSWIVSQVNKALS---TSSKPHSFIGVLDIYGFETFELNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIEAKMGLLDLLDEECTMPKGSDDSWAQKLYNTHLKK--SSHFEKPRMSNKAFIILHFADKVEYQCDGFLEKNKDTVNEEQINVLKASKFSLLLELFQDEESPAAPNTTASSGRAK---------FGRSTQS------FREHKKSVGLQFRNSLHLLMETLNATTPHYVRCIKPNDVKAPFMMDPHRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYQVLMTKKEILL----------DRKLTCQSVLERLVQNKDKYQFGKTKIFFRAGQVAYLEKLRADKLRTACIHIQKTIRCWLARKKYLRIRQAAITLQKYTRGHQAR---CLCKTLRRTRAAVVFQKNTRMWAARRQYLRQKTAAVLIQRILRGYTARLEYKRLVCEHKALLIQRWVRGFLARWRYRRIKRAVVYLQCCVRRMLARRELKKLKIEARSVEHYKKLNYGMENKIMQLQRKLDEQHKENRELSEQIGAIESHSVVELEKLHVQLKTLQEAEEEARHREDLVTSLQEELELVRRELEKNK------------------EMVVELNEKNTMLKSEKEEMNRLIQEQEQQIREKSEVTNEDVTENLQTQLNEERFRYQNLLTEHLKLEERYADLRSEK-EAAEISTAGDSRADSGYSSSQSESIHS----SMLTGSEVSSLEKEDAV--QVAADVSLLLKLQRRVAELEKEN-MDMQSEMDTKEEQLVLEKAKELEDCRK--TLGAERDYEALKRQE--LESDNKKLKKDLQELRQSLSKGTGSKVTSPGGR-AYNVILEQLNSTNEELEVRKEEVLILRSQLVSHEAFKHKELGTEGDSGDSSRSPTLDLTELNEDGELWMAYESLKETN----------------------------------------------RILVSQLQTQRESHEKETESLRAELQHLKAELDQQQQMLSQSLELPHDARIQASLQHEISRLTQQN-------------------------MDLLEQMGKQDKMVRKLKKQLKIYMKKFGEPEGVHFEQSSPEN--MLAESGRTVSIVRKERDFQGMLEYRREDENKLFKTLITDLKPRGVAVNLVPGLPAYILFMCLRHADYANDDLRVSTLLNTSINSIKNTLKKRGD-FESIS--FWLANT----CRFLHCLKQYSGEEGYSKHNTPRQNEHCLTNFDLSEYRQVLSDLAIQIYQQLIRVIENILQPMIAPAMLEQETIQGVMGVKPTGMRKRTSSFHE------ENSHSLESILKQLDGFYFTLLQHGNDAEVVRQVIKQQFYVICSVTLNNLLLRKDMCSWSKGLQIRYNVCQLEEWLLDKDLQGSGARESLEPLIQAAQLLQIKKKSQDDADAICTMCTALTTQQIVKILSLYTPVNEFEERVSISFIKTIQTLLKD--------RKESSQLLMDAKIIFPVTFPFNP-------SSVALETLQLPSRLNLS-FLTRV------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P21271-1", "uniprot_id": "MYO5B_MOUSE", "id": "P21271-1", "name": "Unconventional myosin-Vb", "aln": "--MSYSELYTRYTRVWIPDPDEVWRSAELTK-DYKEGDKSLQLRLEDDTILEYPVD----VQNNQVPFLRNPDILVGENDLTALSHLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLP-IYGQDVIYAYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASD--------TNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKFIEIGFDKKY---HIIGANMRTYLLEKSRVVFQADDERNYHIFYQLCAAASLPEFKELALTCAEDFFYTAHGGNTTIEGVNDADDFEKTRQALTLLGVRDSHQISIFKIIASILHLGSVEIQS-------ERDGDSCSISPQDEHLSNFCSLLGIEHSQMEHWLCHRKLVTTSETYVKTMSLQQVVNARDALAKHIYAQLFSWIVEHINKALH---TSHKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYERHSN---SQHFQKPRMSNTAFIVNHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDSAPATNTAKNRSSSKIN--VRSSRPLIKVP------NKEHKKSVGYQFRTSLNLLMETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWTYHDFFNRYRVLMKKRELTN-T--------DKKNICKSVLESLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFREATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLAR---RLAEHLRRTRAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNYRQVLMEHKATIIQKYARGWMARKRFLRERDAAIVIQCAFRRLKARQELKALKIEARSAEHLKRLNVGMENKVVQLQRKIDDQNKEFKTLSEQLSAVTSSHAVEVEKLKKELAHYQQNQE----ADTSLQ-LQEEVQSLRTELQKAHSERRVLEDAHNKENGELRKRVADLEHENALLKDEKEYLNNQILCQSK---AESSQSSVEENLLMKKELEEERSRYQNLVKEYSQLEQRYENLRDEQ-------TPGHRKNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGIEKAAMDMTVFLKLQKRVRELEQER-KKLQAQLEK-GQQDSKKGQVEQQNNGLDVDQDADIAYNSLKRQE--LESENKKLKNDLNELRKAVADQAMQDNSTHSSPDSYSLLLNQLKLANEELEVRKEEVLILRTQIMNAD--QRRLSGKNMEPNINARTSWPNSEKHVDQEDAIEAYHGVCQTN----------------------------------------------RLLEAQLQAQSLEHEEEVEHLKAQVEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNEN-------------------------LDFKELVEKLEKNERKLKKQLKIYMKKVQDLEAAQALAQSDR---RHHELTRQVTVQRKEKDFQGMLEYHKEDEALLIRNLVTDLKPQMLSG-TVPCLPAYILYMCIRHADYTNDDLKVHSLLSSTINGIKKVLKKHNDDFEMTS--FWLSNT----CRFLHCLKQYSGDEGFMTQNTAKQNEHCLKNFDLTEYRQVLSDLSIQIYQQLIKIAEGLLQPMIVSAMLENESIQGLSGVRPTGYRKRSSSMVD-----GENSYCLEAIVRQMNSFHTVLCDQGLDPEIILQVFKQLFYMINAVTLNNLLLRKDACSWSTGMQLRYNISQLEEWLRGKNLHQSGAVQTMEPLIQAAQLLQLKKKTHEDAEAICSLCTSLSTQQIVKILNLYTPLNEFEERVTVSFIRTIQAQLQE--------RNDPQQLLLDSKHVFPVLFPYNP-------SALTMDSIHIPACLNLE-FLNEV------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P70569-1", "uniprot_id": "MYO5B_RAT", "id": "P70569-1", "name": "Unconventional myosin-Vb", "aln": "--MTYSELYSRYTRVWIPDPDEVWRSAELTK-DYKDGDESLQLRLEDDTILDYPID----VQNNQVPFLRNPDILVGENDLTALSHLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLP-IYGQDVIYAYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASD--------TNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIEIGFDKKY---HIIGANMRTYLLEKSRVVFQADDERNYHIFYQLCAAASLPEFKELALTCAEDFFYTAHGGNTTIEGVDDAEDFEKTRQALTLLGVRESHQISIFKIIASILHLGSVEIQA-------ERDGDSCSISPQDEHLSNFCRLLGIEHSQMEHWLCHRKLVTTSETYVKTMSLQQVVNARNALAKHIYAQLFSWIVEHINKALQ---TSLKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYERHSN---SQHFQKPRMSNTAFIVIHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFRDDEDSVPATNTAKSRSSSKIN--VRSSRPLMKAP------NKEHKKSVGYQFRTSLNLLMETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWTYHDFFNRYRVLMKKRELANTT--------DKKNICKSVLESLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFREATIMIQKTVRGWLQRVKYRRLRAATLTLQRFCRGYLAR---RLTEHLRRTRAAIVFQKQYRMLKARRAYCRVRRAAVIIQSYTRGHVCTQKLPPVLTEHKATIIQKYARGWMARRHFQRQRDAAIVIQCAFRRLKARQALKALKIEARSAEHLKRLNVGMENKVVQLQRKIDDQNKEFKTLSEQLSAVTSTHAMEVEKLKKELARYQQNQE----ADPSLQ-LQEEVQSLRTELQKAHSERRVLEDAHNRENGELRKRVADLEHENALLKDEKEHLNHQILRQSK---AESSQSSVEENLLIKKELEEERSRYQNLVKEYSQLEQRYENLRDEQQ------TPGHRKNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGIEKAAMDMTVFLKLQKRVRELEQER-KKLQVQLEK-EQQDSKKVQVEQQNNGLDVDQDADIAYNSLKRQE--LESENKKLKNDLNERWKAVADQAMQDNSTHSSPDSYSLLLNQLKLANEELEVRKEEVLILRTQIMNAD--QRRLSGKNMEPNINARTSWPNSEKHVDQEDAIEAYHGVCQTNSQT--------------------EDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQNLKHEEEVEHLKAQVEAMKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNEN-------------------------LDFKELVEKLEKNEKKLKKQLKIYMKKVQDLEAAQALAQSDR---RHHELTRQVTVQRKEKDFQGMLEYHKEDEALLIRNLVTDLKPQMLSG-TVPCLPAYILYMCIRHADYTNDDLKVHSLLSSTINGIKKVLKKHNEDFEMTS--FWLSNT----CRLLHCLKQYSGDEGFMTQNTAKQNEHCLKNFDLTEYRQVLSDLSIQIYQQLIKIAEGLLQPMIVSAMLENESIQGLSGVRPTGYRKRSSSMVD-----GENSYCLEAIIRQMNFFHTVLCDQGLDPEIILQVFKQLFYMINAVTLNNLLLRKDACSWSTGMQLRYNISQLEEWLRGKNLQQSGAVQTMEPLIQAAQLLQLKKKTQEDAEAICSLCTSLSTQQIVKILNLYTPLNGFEERVTVSFIRTIQAQLQE--------RSDPQQLLLDSKHMFPVLFPFNP-------SALTMDSIHIPACLNLE-FLNEV------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ULV0-1", "uniprot_id": "MYO5B_HUMAN", "id": "Q9ULV0-1", "name": "Unconventional myosin-Vb", "aln": "--MSVGELYSQCTRVWIPDPDEVWRSAELTK-DYKEGDKSLQLRLEDETILEYPID----VQRNQLPFLRNPDILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLP-IYGQDVIYTYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASE--------TNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRY---HIIGANMRTYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQA-------ERDGDSCSISPQDVYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALH---TSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDRHSS---SQHFQKPRMSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPVPATTPGKG-SSSKIS--VRSARPPMKVS------NKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKRELAN-T--------DKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLAR---RLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPG----EDTSLR-LQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSK---DEFAQNSVKEN-LMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQ--TPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQER-KKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQE--LESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQIVSAD--QRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKT--------------------EDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNEN-------------------------LDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSER---KRHELNRQVTVQRKEKDFQGMLEYHKEDEALLIRNLVTDLKPQMLSG-TVPCLPAYILYMCIRHADYTNDDLKVHSLLTSTINGIKKVLKKHNDDFEMTS--FWLSNT----CRLLHCLKQYSGDEGFMTQNTAKQNEHCLKNFDLTEYRQVLSDLSIQIYQQLIKIAEGVLQPMIVSAMLENESIQGLSGVKPTGYRKRSSSMAD-----GDNSYCLEAIIRQMNAFHTVMCDQGLDPEIILQVFKQLFYMINAVTLNNLLLRKDVCSWSTGMQLRYNISQLEEWLRGRNLHQSGAVQTMEPLIQAAQLLQLKKKTQEDAEAICSLCTSLSTQQIVKILNLYTPLNEFEERVTVAFIRTIQAQLQE--------RNDPQQLLLDAKHMFPVLFPFNP-------SSLTMDSIHIPACLNLE-FLNEV------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P3E4-1", "uniprot_id": "A0A8M9P3E4_DANRE", "id": "A0A8M9P3E4-1", "name": "Unconventional myosin-Vb", "aln": "--MREHELYVKYTRVWIPDPDEVWRSAEIIK-DYKEGDTVLHLKLEDESTLEYPIG----SKDNPLPFLRNPDILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLH-IYGEEVINAYSGQNMGDMDPHIFAVAEEAFKQMARDEKNQSIIVSGESGAGKTVSAKYAMRFFATVGGSAND--------TNVEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDRRY---HIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASCSLPEFKDLTLTSAEDFTYTSLGENIFIEGVNDAEDLVKTREALTMLGVKENHQMSIFKIIASILHLGNVEIVQ-------ERDGESCHINRNDTHLHHFCRLLGIEQEQMENWLCRRKLVTTSETYVKNMPHSQAVNARDALAKHIYAHLFDWIVEHINKSLH---TSTKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYSKHSG---SGHFEKPRMSNKSFIVVHFADKVEYQCDGFLEKNRDTVYEEQINILKASKFQLVADLFDDAKDAAPHP----GSKTSRIN--VRPAKPAPKGH------NREHRKTVGTQFRNSLHLLMETLNATTPHYVRCIKPNDYKESFVFDSRRAVQQLRACGVLETIRISAAGYPSRWTYPDFFSRYRVLMTKKDLSV-G--------DKKQVCKNLLEILIKDPDKFQFGKTKIFFRAGQVAYLEKLRADKFRFACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLAR---RYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYRRVRAKRQLKQLKIEARSAEHFKKLNVGMENKIVQLQKKMDNQSKELKSQNENLAVAKTVLETEVSKLSKELETLRTRQV----AGTQMTSLQEELEKLRAELQEAHAHKKLLEEEFSNEKQGLEQRVEELEKENTVLKKEKEEMNRRIQTSTQ---DQGGDVSQKES-RLQHELDDERQRYQNLVKEYSRLEQRYENLQEDMSSMKF--HPGHRRNPSNQSSLGSDSNYPSISLSEVGDTDDTIQQVEEMGIEKAAMDLSVFMKLQKRVRELEQER-KRLQTNLDKVEELSKRKG-SEAKNSTSEDDINADLAYNSLKRQE--LETENKKLKNDLNELRKAVADRASENNSSNELQDGYNLLLSQLKAANEELDVRKEEVLMLKTQIVNS----TRQTENLNHINSNDVSEWTDNKSPVNTEDRVDAPASKNKAQ------------------------DWGYLNEDGELGLAYQGLKQVARLLETQLQTQTRQHRDELEALHTQIELLKDNLEKKQDMLDHFSTLSPDALVEFSVQQEITRLTNEN-------------------------LDLKELVEKLEKNEKKLKKQLRIYMKKVQELEVTQATKS-------RPELTRQFTVQRREKDFEGMLEYYKEDEALLVKTLVTDMKPNAVSA-TVPCLPAYILFMCIRHADYINDDQKVHSLLTATINAIKKVLKKNNDDFEMTS--FWLANA----SRLLHCLKQYSGDEAFMTQNSAKQNEHCLKNFDLAEYRQVLSDLSIQIYQQLVKVAEANMQPMIVSAMLESESIPSLAGVKPMGYRNRSSSVDCESG--GPAGYTLQALIKQLAQFYSTMADHGLDPEISQQVLRQLFYSINAVTLNNLLLRKDVCSWSTGMQLRYNISQLEEWLRGKNLHQCGAVATMEPVIQAAQLLQVKKKTSQDAEAICSLCTALSLQQIVKILNLYTPLNEFEERVTVSFIRDIQNRLQD--------RIENNQLLADTKYTFPVLFPYTP-------SNLSLETIHIPASLSLD-FLTRENF----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E9Q1F5-1", "uniprot_id": "E9Q1F5_MOUSE", "id": "E9Q1F5-1", "name": "Unconventional myosin-Va", "aln": "--MAVAELYAQYNRVWIPDPEEVWKSAEIAK-DYRAGDRVLRLLLEDGMELEYPVD----PGS--LPPLRNPDILVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLP-IYGDAIIHAYSGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSSSN--------AHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDERN---QIIGANMRTYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVNDRADMVETQKTFTLLGFKKDFQMDVFKILAAILHLGNVQVT--------TVGNERSSVSEDDSHLKVFCELLGLETSKVAQWLCNRKIVTSSETVVKPMTRPQAINARDALAKKIYAHLFDFIVEQINQALH---FSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNLHVFKLEQEEYMKEDIPWTLIDFYDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNK--NSLFEKPRMSNSSFIIQHFADKVEYQCEGFLEKNRDTVYDMLVEILRASKFHLCAAFFQESPVPSSPFGAMIT---------VKSAKQVIKPN------TKHFRTTVGNKFRSSLYLLMETLNATTPHYVRCIKPNDEKMPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYLEFYSRYGILMTQQELSLS---------DKKEVCKVVLHRLIQDSNQYQFGRTKIFFRAGQVAYLEKLRLDKLRQDCIMIQKHVRGWLQRRKFLRERQAALTIQRYFRGQQTVRKAITATALKEAWAAIILQKYCRGYLVRNLYQLIRVATITIQAHTRGFLARRRYRKLLQEHKAVILQKYARAWLARRRFQNIRRFVLNIQLTYR-------------------------------VQRLQKKLEDQNRENHGLVEKLTSLAALRVGD----------------------------LEKVQKLEAELEKAATHRHSYEEKGRRYRDTVEERLSKLQKHNAELELQRERAEQMLQEKSEELKEKMDKLTRQLFDDVQKEEQQRLVLEKGFELKTQAYEKQIESLREEIKALKDERSQLHHQLEEGQVTSDRLKGEV----ARLSKQAKTISEFEKEIELLQAQKIDVEKHVQSQKREMRERMSEVTKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEGLNFKVVHLSQ------EINHLQKLFREETDINESIRHEVTRLTSENMMIPDFKQQISELERQKQDLESRLKEQAEKIEGKLEEPFSHLNRIREE---------------------------------------------ERMQGRAVEAQSEMHPEGKERLVGAIHEPHEAIKFPK------KQPEAEEEVESILQQEASRLSLEK-------------------------RDLEEELDMKDRMIRRLQDQVKTLTKTTEKAN--------------------HVHLPSGSREYLGMLEYKKEDEGKLIQNLILDLKPRGVVVNMIPGLPAHILFMCVRYADSLNDANMLKSLMNSAINGIKHVVKEHFEDLEMLS--FWLSNT----CHFLNCLKQYSGEEEFMKYNSPQQNKNCLNNFDLTEYRQILSDVAIRIYHQFIIVMENNLQPIIVPGMLEYESLQGISGLKPTGFRKRSSSIDD------TDAYTMTSILQQLSYFYSTMCQNGLDPEIVRQAVKQLFYLVGAVTLNSLLLRKDMCSCRKGMQIRCNISFLEEWLKDKNVQSSLAKETLEPLSQAAWLLQVKKTTDSDAKEIAQCCTSLSAVQIIKILNSYTPIDDFEKRVNPSFVRKVQALLNN--------RGDSAQLMLDTKYLFQVTFPFTA-------SPHALEMTQIPSSFKLG-FLRRL------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M111-1", "uniprot_id": "F1M111_RAT", "id": "F1M111-1", "name": "Unconventional myosin-Va", "aln": "--MAVAELYAQYNRVWIPDPEEVWKSAEIAK-DYRVGDQVLRLLLEDGTELDYPVD----PGS--LPPLRNPDILVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLP-IYGDAIIHAYSGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSSSN--------AHVEEKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDERN---QIIGANMRTYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVDDRADMAETQKTFTLLGFKKDFQMDVFKILAAILHLGNVQVT--------TVGNERSAVSEDDSHLKVFCELLGLETIKVAQWLCNRKIVTSSETVVKPMTRPQAINARDALAKKIYAHLFDFIVEQINQALH---FSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNLHVFKLEQEEYMKEDIPWTLIDFYDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNK--NSLFEKPRMSNSSFIIQHFADKVEYQCEGFLEKNRDTVYDMLVEVLRASKFHLCAAFFQESPVPSSPFGAMIT---------VKSAKQVIKPN------TKHFRTTVGNKFRSSLFLLMETLNATTPHYVRCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYLEFYSRYGVLMTQQELSLS---------DKKEVCKVVLHRLIQDSNQYQFGRTKIFFRAGQVAYLEKLRLDKLRQGCIVIQKHVRGWLQRKKFLRERRAALTIQQYFRGQQTVRKAITATALKEAWAAIILQKHCRGYLVRNLYQLIRVATITIQAHTRGFLARRRYRKLLQEHKAVILQKYARAWLARRRFQNIRRFVLNIQLTYR-------------------------------VQRLQKKLEDQNRENHGLVEKLTSLAALRVGD----------------------------LEKVQRLEAELEKAATHRHSYEEKGRRYRDSMEERLSKLQKHNAELESQRERAEQSLQERTEELKEKMDQLTRQLFDDVQKEEQQRLLLEKSFELKTQAYEKEIESLREEIKALKDERTQLHHQLEEGRVTSDSLKGEV----ARLSKQAKTISEFEKEIELLQAQKIDVEKHVQSQKREMRERMSEVTKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEGLNFKVVHLSQ------EINHLQKLFREETDINESIRHEVTRLTSENMMIPDFKQQISELERQKQDLESRLKEQAEKMEGKQEEPFSHLNRGLEE---------------------------------------------EGRQGKAVEAQSETHPEGKERLVGKIQEPQEAIKFPK------KQAEAEEEVESILRQEASRLSLEN-------------------------RDLEEELDMKDRMIRKLQDQVKTLTRTIEKAN--------------------SVPLPSGSREYLGMLEYKKEDETKLIQNLILDLKPRGVVVNMIPGLPAHILFMCVRYADSLNDANMLKSLMNSAINGIKHVVKEHFEDLEMLS--FWLSNT----CHFLNCLKQYSGEEEFMKCNSPQQNKNCLNNFDLTEYRQILSDVAIRIYHQFILVMENNLQPIIVPGMLEYESLQGISGLKPTGFRKRSSSIDD------TDAYTMTSILQQLSYFYSTMCQNGLDPEIVRQAVKQLFYLIGAVTLNSLLLRKDMCSCRKGMQIRCNISFLEEWLKDKNLQNSLAKETLEPLSQAAWLLQVKKTTDSDAKEISQCCTSLSAVQIIKILNSYTPIDDFEKRVNPSFVRKVQALLNN--------RGDSSQLMLDTKYLFQVTFPFTA-------SPHALEMTQIPSSFKLG-FLRRL------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQX4-1", "uniprot_id": "MYO5C_HUMAN", "id": "Q9NQX4-1", "name": "Unconventional myosin-Vc", "aln": "--MAVAELYTQYNRVWIPDPEEVWKSAEIAK-DYRVGDKVLRLLLEDGTELDYSVN----PES--LPPLRNPDILVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLP-IYGDAIIHAYSGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSN--------AHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQN---QIIGANMSTYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVNDRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQIT--------AVGNERSSVSEDDSHLKVFCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQALQ---FSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPWTLIDFYDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNR--NPLFEKPRMSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPPSPFGSMIT---------VKSAKQVIKPN------SKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQELSFS---------DKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYR-------------------------------VQRLQKKLEDQNKENHGLVEKLTSLAALRAGD----------------------------VEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEV----ARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQ------EINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEE---------------------------------------------EGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLK------KQFETESEVKCNFRQEASRLTLEN-------------------------RDLEEELDMKDRVIKKLQDQVKTLSKTIGKAN--------------------DVHSSSGPKEYLGMLQYKREDEAKLIQNLILDLKPRGVVVNMIPGLPAHILFMCVRYADSLNDANMLKSLMNSTINGIKQVVKEHLEDFEMLS--FWLSNT----CHFLNCLKQYSGEEEFMKHNSPQQNKNCLNNFDLSEYRQILSDVAIRIYHQFIIIMEKNIQPIIVPGMLEYESLQGISGLKPTGFRKRSSSIDD------TDGYTMTSVLQQLSYFYTTMCQNGLDPELVRQAVKQLFFLIGAVTLNSLFLRKDMCSCRKGMQIRCNISYLEEWLKDKNLQNSLAKETLEPLSQAAWLLQVKKTTDSDAKEIYERCTSLSAVQIIKILNSYTPIDDFEKRVTPSFVRKVQALLNS--------REDSSQLMLDTKYLFQVTFPFTP-------SPHALEMIQIPSSFKLG-FLNRL------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z6Z8-1", "uniprot_id": "A1Z6Z8_DROME", "id": "A1Z6Z8-1", "name": "", "aln": "-MSSEEMLYAQGAKIWVPHADLVWESATLEE-SYRKGAGFLKICTDSGKLKEVKLK----ADGSDLPPLRNPAILVGQNDLTTLSYLHEPGVLHNLRVRFCERQIIYTYCGIILVAINPYAEMP-LYGPSIIRAYRGHAMGDLEPHIFALAEEAYTKLERENCNLSIIVSGESGAGKTVSAKYAMRYFAAVGGSESE--------TQVERKVLASSPIMEAFGNAKTTRNDNSSRFGKFTKLLFRNQMGVMFLQGATMHTYLLEKSRVVYQAQGERNYHIFYQLCAAR--SKYPELVLDHQDKFQFLNMGGAPEIERVSDAEQFNETVQAMTVLGFSIQQIADIVKILAGILHLGNIQVSKKFNEGSEEEDSDSCDIFHNDIHLQITADLLRVSADDLRRWLLMRKIESVNEYVLIPNSIEAAQAARDALAKHIYAKLFQYIVGVLNKSLN---NGSKQCSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNQHVFKLEQEEYLKEGITWTMIDFYDNQPCIDLIESRLGVLDLLDEECRMPKGSDESWAGKLIG-KCNK--FPHFEKPRFGTTSFFIKHFSDTVEYDVNGFLEKNRDTVSKELTQVLSESNMSLAKQVMTLEEIDTLCVDSAKSSTLGGRVVISAGRKQQGNDTRRRVVPSKQHRKTVGSQFQESLASLISTLHATTPHYVRCIKPNDDKVAFKWETAKIIQQLRACGVLETVRISAAGFPSRWLYPDFYMRYQLLVYRSKLDKN---------DMKLSCRNIVMKWIQDEDKYRFGNTQIFFRAGQVAFLEQVRANLRKKYITIVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLAR---ERTQKMREARAGLILSKYARGWLCRRRYLRLRHSISGIQTYARGMLARNKFHAMRDHYRAVQIQRFVRGALARRAYQKRRRNIIICQAAIRRFLARRKFKRMKAEAKTISHMENKYMGLENKIISMQQRIDELNRDNSNLKHKTSEISVLKMKLELKKTLEAEFKN--------VKAACQDKDKLIEALNKQLEAERDEKMQLLEENGHAQEEWISQKQTWRQENEELRRQIDEIIDMAK------NAEVNQRNQEDRMLAEIDNRELNEAYQRAIKDKEVIENENFMLKEELSRLTAGSFSLHARKASNASSQNEDDVGY----ASAKNTLDINRPPDLLSKNYSYNDSTSLVVKLRSILEEEKQKHKVLQEQYIKLSSRH-------------------KPTEDSFRVSE--LEVENEKLRSEYDQLRTSIKHG-----------VEINELNAQHAALQEEVRRRREECIQLKAVLLQQS------------QSMRSLEPESLQMRGNDVNELMEAFHSQKLIN----------------------------------------------RQLESELKAITEEHNSKLVEMTQEIERLNNEKDELQKVMFESIDEFEDSNVDT-LRQNDRYLRREL-------------------------QKAVAQFLLVQEELKLANAKLKAYRQDGGQLEHKIEEEMIRNKSNGTSADVGANVTKQKSQNPQGLMKFHSSDLDKILQRLLSALTPRTVVG-LLPGFPAYLIFMCIRYTDLTNADDDVRELLSKFVIQIKKMHR-TPHPIENRV--IWLVNS----ITLLNLMKQYGDVDEYVKFNTEKQNQQQLKNFNLFEYRRVILDLIVNLYQALIMQIQGLLDPKIVPAILNNDEIQ--RGRQAHGMRSRATSIGASSSPEHGGGPAWKQLIGQLEHFYKQFQHFGLDNCYAEQIFHQLLYFICAVALNCLMLRGDICMWETGMIIRYNIGCIEDWVRSKKMSN-DVLTALAPLNQVSQLLQSRK-SEQDVQTICDLCTSLSTAQVLKVMKSYK-LDDYESEITNVFLEKLTEKLNARQMQ----KSNSDEFTIDQKFIQPFKVVFRY-------SDIKLEDIELPSHLNLDEFLTKI------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P19524-1", "uniprot_id": "MYO2_YEAST", "id": "P19524-1", "name": "Myosin-2", "aln": "------MSFEVGTRCWYPHKELGWIGAEVIKNEFNDGKYHLELQLEDDEIVSVDTKDLNNDKDQSLPLLRNPPILEATEDLTSLSYLNEPAVLHAIKQRYSQLN-IYTYSGIVLIATNPFDRVDQLYTQDMIQAYAGKRRGELEPHLFAIAEEAYRLMKNDKQNQTIVVSGESGAGKTVSAKYIMRYFASVEEENSATVQHQVEMSETEQKILATNPIMEAFGNAKTTRNDNSSRFGKYLEILFDKDT---SIIGARIRTYLLERSRLVYQPPIERNYHIFYQLMAGLPAQTKEELHLTDASDYFYMNQGGDTKINGIDDAKEYKITVDALTLVGITKETQHQIFKILAALLHIGNIEIK---------KTRNDASLSADEPNLKLACELLGIDAYNFAKWVTKKQIITRSEKIVSNLNYSQALVAKDSVAKFIYSALFDWLVENINTVLCNPAVNDQISSFIGVLDIYGFEHFEKNSFEQFCINYANEKLQQEFNQHVFKLEQEEYVKEEIEWSFIEFNDNQPCIDLIENKLGILSLLDEESRLPAGSDESWTQKLYQTLDKSPTNKVFSKPRFGQTKFIVSHYALDVAYDVEGFIEKNRDTVSDGHLEVLKASTNETLINILEGLEKAAKKLEEAKKLELEQAG-----SKKPGPIR------TVNRKPTLGSMFKQSLIELMNTINSTNVHYIRCIKPNADKEAWQFDNLMVLSQLRACGVLETIRISCAGFPSRWTFEEFVLRYYILIPHEQWDLIFKKKETTEEDIISVVKMILDATVKDKSKYQIGNTKIFFKAGMLAYLEKLRSNKMHNSIVMIQKKIRAKYYRKQYLQISQAIKYLQNNIKGFIIR---QRVNDEMKVNCATLLQAAYRGHSIRANVFSVLRTITNLQKKIRKELKQRQLKQEHEYNAAVTIQSKVRTFEPRSRFLRTKKDTVVVQSLIRRRAAQRKLKQLKADAKSVNHLKEVSYKLENKVIELTQNLASKVKENKEMTERIKELQVQVEES---------------------------------------------------------AKLQETLENMKKEHLIDIDNQK------------------SKDMELQKTIENNLQSTEQTLKDAQLELEDMVKQHDELKEESKKQLEELEQTK-----------------------------------------------------------------------------------------------------------------------------------------------KTLVEYQTLNGDLQNEVKSLKEEIARLQTAMSLGT-------------VTTSVLPQTPLKDVMGGGASNFNNMMLENSD-----------------------------------------------LSPNDLNLKSRSTPSSGNNHIDSLSVDRE-----------------NGVNATQINEELYRLLEDT------------------------------------------------------------------------------------------EILNQEITEGLLKGFEVPDAGVAIQLSKRDVVYPARILIIVLSEMWRFGLTKQSESFLAQVLTTIQKVVTQLKGNDLIPSGVFWLANVRELYSFVVFALNSILTEETFKNGMTDEEYKEYVS--LVTELKDDFEALSYNIYNIWLKKLQKQLQKKAINAVVISESLPGFSAGETSGFLNKIFANTE--------EYTMDDILTFFNSIYWCMKSFHIENEVFHAVVTTLLNYVDAICFNELIMKRNFLSWKRGLQLNYNVTRLEEWCKTHGLTD--GTECLQHLIQTAKLLQVRKYTIEDIDILRGICYSLTPAQLQKLISQYQ-VADYESPIPQEILRYVADIVKKEAALSSSGNDSKGHEHSSSIFITPETGPFTDPFSLIKTRKFDQVEAYIPAWLSLPSTKRIVDLVAQQVVQDGH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * *. * .* : . .:. * * : :. . :* **** ** . :***:**:*:**.*** :: *: : : ****.**:*:* **: : :* :* :* *: *:::**:**::***: : .:: * :*:*************:* **:**:* . . : * *:**:.** *:.****************: :: * . : ** : *****:**:*:*. ********** * * * ..: : * * :.* : * .: ::*. :.:*::.:**:*.: . . . : .. * . * : . .*: ::: : .* . .::::** **: ** ::* :* * : :*********** *: *****************:** **********:** * *::*:* **** *:*** ::*:*.*****. :* *:*:.* ** *.***:. . *.: *:: * * :**:***:*** . ::* *. .: . : ::* *: ** *:.*:::*. **:****** * .: : :.**********:***. .:**** : :* ** :*: : . * : :: : : .::::*.*:***:** :*:**::* : : :*. :* : :: :*. :* .. . * : : :* * * :* .* * : : * * : : :.: . :: .. . ...: : . . : : . : . :. *:.: . : :.* * : : :: . : . : ...: * : : : : ** :: : : . :: : *:: :** * .: ::. : : . : .: :. :. : * : : : .:*: : : :: .:: : : . .. * .: : :: : :: : : . : : :: :* *::: : *: :. *: :*:* : : : : *.: *** :* : .* . : * :*: *: *::. * : :*. : ::. : :. . . . . : :*: : * ", "identical_positions": 319, "similar_positions": 370, "identity": "15.91%" }, { "cls_id": "homologset.agr.SGD:S000005854", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63045-1", "uniprot_id": "VAMP2_RAT", "id": "P63045-1", "name": "Vesicle-associated membrane protein 2", "aln": "-------------MSATAATVPP--AAPAGEGGPPAPPP--------------NLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKMMIILGVICAIILIIIIVYFST--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q63666-1", "uniprot_id": "VAMP1_RAT", "id": "Q63666-1", "name": "Vesicle-associated membrane protein 1", "aln": "-------------MSAPAQPPAEGTEGAAPGGGPPGPPP--------------NTTSNRRLQQTQAQVEEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASVFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVIYIFT--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63025-1", "uniprot_id": "VAMP3_RAT", "id": "P63025-1", "name": "Vesicle-associated membrane protein 3", "aln": "-------------MST---------------GVPSGSSA--------------ATGSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAIGISVLVIIVIIIIVWCVS--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18489-1", "uniprot_id": "SYB_DROME", "id": "P18489-1", "name": "Synaptobrevin", "aln": "-------------MENNEAPSPSGSNNNDFPILPPPPNANDNYNQFGDHQIRNNNAAQKKLQQTQAKVDEVVGIMRVNVEKVLERDQKLSELGERADQLEQGASQFEQQAGKLKRKQWWANMKMMIILGVIAVVLLIIVLVSVWPSSSDSGSGGGNKAITQAPPH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9WUF4-1", "uniprot_id": "VAMP8_RAT", "id": "Q9WUF4-1", "name": "Vesicle-associated membrane protein 8", "aln": "-------------MEASG------------------------------------SAGNDRVRNLQSEVEGVKNIMTQNVERILARGENLDHLRNKTEDLEATSEHFKTTSQKVARKFWWKNVKMIVIICVIVLIILILIILFATGTIPT----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1P6T1-1", "uniprot_id": "A0A8M1P6T1_DANRE", "id": "A0A8M1P6T1-1", "name": "", "aln": "----------MADYNTES------------------------------------AAPPSKLNQVQDQVNDVKVILKDNINKVLERGERLDDLIGKTDDLQATADSFQRTSTHVARKMWWRNTKMMIIIGVVVVAIIVLIIVLATQVK------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O70480-1", "uniprot_id": "VAMP4_MOUSE", "id": "O70480-1", "name": "Vesicle-associated membrane protein 4", "aln": "MPPKFKRHLNDDDVTGSVKSERR--------NLLEDDSDEEEDFFLRGPSGPRFGPRNDKIKHVQNQVDEVIDVMQENITKVIERGERLDELQDKSESLSDNATAFSNRSKQLRRQMWWRGCKIKAIMALAAAILLLMIIILIVVKFRT----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0KYT3-1", "uniprot_id": "A0ABK0KYT3_RAT", "id": "A0ABK0KYT3-1", "name": "Vesicle-associated membrane protein 4", "aln": "MPPKFKRHLNDDDVTGSVKSERR--------NLLEDDSDEEEDFFLRGPSGPRFGPRNDKIKHVQNQVDEVIDVMQENITKVIERGERLDELQDKSESLSDNATAFSNRSKQLRRQMWWRGCKIKAIMALAAAILLLMIIILIVVKYRT----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75379-1", "uniprot_id": "VAMP4_HUMAN", "id": "O75379-1", "name": "Vesicle-associated membrane protein 4", "aln": "MPPKFKRHLNDDDVTGSVKSERR--------NLLEDDSDEEEDFFLRGPSGPRFGPRNDKIKHVQNQVDEVIDVMQENITKVIERGERLDELQDKSESLSDNATAFSNRSKQLRRQMWWRGCKIKAIMALVAAILLLVIIILIVMKYRT----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33328-1", "uniprot_id": "SNC2_YEAST", "id": "P33328-1", "name": "Synaptobrevin homolog 2", "aln": "-------------MSSSVPYDPY--------VPPEESN-----------SGANPNSQN-KTAALRQEIDDTVGIMRDNINKVAERGERLTSIEDKADNLAISAQGFKRGANRVRKQMWWKDLKMRMCLFLVVIILLVVIIVPIVVHFS-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ::: . :: *: :: *.:.* : ::: * : *. : :: :: ** . *: ::::::: ", "identical_positions": 8, "similar_positions": 34, "identity": "4.85%" }, { "cls_id": "homologset.agr.SGD:S000005857", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYV8-1", "uniprot_id": "DPOG1_RAT", "id": "Q9QYV8-1", "name": "DNA polymerase subunit gamma-1", "aln": "MSRLLWKKVAGAKVASGPVPATGRWVSSSVLDPVPSDGQ-----------------PQSQMPSSENGQLRLNPLHIQMLSRGLHEQIFG-CGGDVPDEAAVQRS---IEHLRKHGLWGQPTTPLPDVQLRLPRLFGGNLDQHFRLLAQKQSLPYLEAAASLSEAQLPPQ-PRKWVWAEGWTRYGPE-GEAEPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSRRLVEERYSWTSQLSPADLIPLGVSASASSSTQQDWQEQ---LVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWMGAKQGKHKTQHPTK-RGQKSQKNANGPAISSWDWMDISSANNLADVHNLYVGGPRLAKEPRELFVKGSMRDIRENFQDLMEYCARDVWATFEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQN-WERYLTEAQSTYEELQREMKKSLMELANDACQLLSG-ERYKEDPWLWDLEWDLQEFKQKKAKKVKK-TASASKLPIEGAGPFGDPMDQEDPGPPSEEEELQQNIMAHTRLQQLKSTTDLLPKRPQHLPGHPGWYRKLCPR-----------LDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSDSHGWGYLVPGRRDNLTELPVSPTEESAAVTCPYRAIESLYRRHCLDQGKQQLETQETDLAEEFLLTD-SAMWQTVEELGCLDVEAEATVE---SSGLSQPLVPPTACAPKTSQPTYHHGNGPYNDVDIPGCWFFKLPHKDGNNYNVGSPFAKDFLPKMEDGTLQAG-PGGARGPRALEINKMISFWRNAHKRISSQMVV---WLPRSALPRAVTRHPSFDEESHYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYVLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTAATVGISREHAKVFNYGRIYGAGQSFAERLLMQFNHRLSRQEAADKAQQMYAVTKGLRRYRLSDDGEWLVKQLNVPVDRTEDGWVSLQDLRKIRREASRKSRWKKWEVVTERAWTGGTESEMFNKLESIAMSDTPRTPVLGCCISRALEPS---VVQGEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDQCLRKEVTMDCKTPSNPTGMERKYGIPQGEALDIYQIIELTKG-SLEKRSQPGP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54099-1", "uniprot_id": "DPOG1_MOUSE", "id": "P54099-1", "name": "DNA polymerase subunit gamma-1", "aln": "MSRLLWKKVAGAKVASGPVPATARWVASSVLDPVPSDGR-----------------PPSQMPSSENGQLRLNPLLIQMLSRGLHEQIFG-CGGEMPDEAAVQRS---VEHLQKHGLWGQPATPLPDVELRLPRLFGGNLDQHFRLLAQKQSLPYLEAAASLLEAQLPPE-PKSWAWAEGWTRYGPE-GEAEPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSRRLVEERYSWTSQLSPADLIPLGGSTSASSSTKQDGQEQ---LVVGHNVSFDRAHIREQYLIQDSRMRFLDTMSMHMAISGLSSFQRSLWMGAKQGKHKNPAAHKARAEVPEESQWSSESSSWDWMDISSANNLADVHNLYVGGPPLEKEPRELFVKGSMRDIRENFQDLMQYCARDVWATFEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQN-WERYLTEAQNTYEELQREMKKSLMDLANDACQLLSG-ERYKEDPWLWDLEWDLQEFKQKKAKKVKK-PASASKLPIEGAGPFGDPMDQEDPGPPSEEEELQRSVTAHNRLQQLRSTTDLLPKRPQHLPGHPGWYRQLCPR-----------LDDPAWAPGPSLLSLQMRVTPKLMALTWDGFPLHYSDSHGWGYLVPGRRDNLTEPPVSPTVESAAVTCPYRAIESLYRKHCLEQGKQQLEPQEVDLAEEFLLTDNSAMWQTVEELGCLDVEAEAKME---NSGLSQPLVLPAACAPKSSQPTYHHGNGPYNDVNIPGCWFFKLPHKDGNNYNVGSPFAKDFLPKMEDGTLQAG-PGGASGPRALEINKMISFWRNAHKRISSQMVV---WLPRSALPRVVTRHPAFDEEGHYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYVLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTAATVGISREHAKIFNYGRIYGAGQSFAERLLMQFNHRLTRQEAAEKAQQMYAVTKGLRRYRLSADGEWLVKQLNLPVDRTEDGWVSLQDLRMIRREASRKSRWKKWEVAAERAWTGGTESEMFNKLESIAMSDTPRTPVLGCCISRALEPS---VVQGEFITSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDQCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTKG-SLEKRSQPGP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54098-1", "uniprot_id": "DPOG1_HUMAN", "id": "P54098-1", "name": "DNA polymerase subunit gamma-1", "aln": "MSRLLWRKVAGATVGPGPVPAPGRWVSSSVPASDPSDGQRRRQQQQQQQQQQQQQPQQPQVLSSEGGQLRHNPLDIQMLSRGLHEQIFG-QGGEMPGEAAVRRS---VEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPK-PPAWAWAEGWTRYGPE-GEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVPTGASSPTQRDWQEQ---LVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKQGKHKVQPPTKQGQKSQRKARRGPAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQN-WERYLAEAQGTYEELQREMKKSLMDLANDACQLLSG-ERYKEDPWLWDLEWDLQEFKQKKAKKVKKEPATASKLPIEGAGAPGDPMDQEDLGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPR-----------LDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLVPGRRDNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEQGKQQLMPQEAGLAEEFLLTDNSAIWQTVEELDYLEVEAEAKMENLRAAVPGQPLALTARGGPKDTQPSYHHGNGPYNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAG-PGGASGPRALEINKMISFWRNAHKRISSQMVV---WLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLRWYRLSDEGEWLVRELNLPVDRTEGGWISLQDLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPS---AVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTKG-SLEKRSQPGP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27607-1", "uniprot_id": "DPOG1_DROME", "id": "Q27607-1", "name": "DNA polymerase subunit gamma-1, mitochondrial", "aln": "MQFHLIRKYA-SKVSREHYASSSVKIFRRVKPPQKVNKP-----------------KKPENVENGPTEYAENLVKVQMISRNLHAQLFP-QAPRSISEQQVASAKVYKDELRRHGVDIESSAPVSDVQLKLPALRGANIEEHFHNIAKEQVQPYEELLLPLVQCEQLPKRPKRWAFHTGWTAYDPEDGTATPVDHPLEKGLVFDVEVCVSEGQAPVLATAVSTKRWYSWVSSKLTKHRLS-VEKLEPLDVDTDSERPHYTTDELIPLGTTGPGLVVGHNVSYDRARLKEQYLTEDTGTRFVDTMSLHMCVSGVTSYQRAMLKSKKE----------------------PAAEDLGWLEQSSLNSLVEVHRLYCGGDTLSKEPRNIFVEGTLEQVRQSFQSLTNYCASDVEATHRILRVLYPLYAERFPHPASLAGMLEMGSAYLPVNSN-WERYIREAQLTYEDLSIEAKYHLGRRAEEACSLLLD-DQYRQNLWLWDEDWSVQELKLKQPPKRKP-------LP---------TVELKDSGNTPEERRLQ------AKFQHLYDQQALLPARRPLLPGYPLWYRKLCRKPPAKRADEILEDDEEPWSPGASEISTGMQIAPKLLSLCWEGYPLHYEREQGWGFLVPFRSD--SEGVDRLPMEQLLAHCPVPEFARLSASKAESDMAFDMLPG-----------------QVEQHLGKREHYKKLSQK------------------QQRLETQYQGSGVWCNKVLDDCCFFLKLPHKNGPSFRVGNPLSKDFLNKFAENVLSSGDPSCQAAARVIDIARMMSYWRNNRDRIMGQMVV---WLDSQQLPNEFTGEKCQP--IAYGAICPQVVACGTLTRRAMEPTWMTASNSRPDRLGSELRSMVQAPPGYRLVGADVDSQELWIASVLGDAYACGEHGATPLGWMTLSGSKSNGSDMHSITAKAVGISRDHAKVINYARIYGAGQLFAETLLRQFNPTFSASEAKAKAMKMFSITKGKRVYRLR--EEFHDELEDRAYSSYEASRLAIQRNRTLAEVFHRPN------------WQGGTESAMFNRLEEIATGSQPRTPFLGGRLSRALEADTGPEQEQRFLPTRINWVVQSGAVDFLHLMLVSMRWLMGS---HVRFCLSFHDELRYLVKEELSPKAALAMHITNLMTRSFCVSRIGLQDLPMSVAFFSSVEVDTVLRKECTMDCKTPSNPHGLRIGYGIQPGQSLSVAEAIEKAGGNDVSQWDWIKKS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15801-1", "uniprot_id": "DPOG_YEAST", "id": "P15801-1", "name": "DNA polymerase gamma", "aln": "MTKLMVRSECMLRMVRRRPLRVQFCARWFSTKKNTAEAP------------------------------RINPVGIQYLGESLQRQVFGSCGGKDEVEQSDKLMELSKKSLKDHGLWGKKTLITDPISFPLPPLQGRSLDEHFQKIGRFNSEPYKSFCEDKFTEMVARP--AEWLRKPGWVKYVPG-MAPVEVAYPDEELVVFDVETLYNVSDYPTLATALSSTAWYLWCSP-----------------FICGGDDPAALIPLNTLNKEQ---VIIGHNVAYDRARVLEEYNFRDSKAFFLDTQSLHIASFGLCSRQRPMFMKNNKKK-------EAEVESEVHPEISIEDYDDPWLNVSALNSLKDVAKFHCKID-LDKTDRDFFASTDKSTIIENFQKLVNYCATDVTATSQVFDEIFPVFLKKCPHPVSFAGLKSLSKCILPTKLNDWNDYLNSSESLYQQSKVQIESKIVQIIKDIVLLKDKPDFYLKDPWLSQLDWTTKPLRLTKKG---------------------------------------------------------VPAKCQKLPGFPEWYRQLFPS----------------KDTVEPKITIKSRIIPILFKLSWENSPVIWSKESGWCFNVP------HEQVETYKAKNYVLADSVSQEEEEIRTHNLG--------------------------------------------------------------------------------LQCTGVLFKVPHPNGPTFNCTNLLTKSYNHFFEKGVLKSE---SELAHQALQINSSGSYWMSARERIQSQFVVPSCKFPNEFQSLSAKSSLNNEKTNDLAIIIPKIVPMGTITRRAVENAWLTASNAKANRIGSELKTQVKAPPGYCFVGADVDSEELWIASLVGDSIFN-VHGGTAIGWMCLEGTKNEGTDLHTKTAQILGCSRNEAKIFNYGRIYGAGAKFASQLLKRFNPSLTDEETKKIANKLYENTKG----------------------KTKRSKLFKK------------------------FWYGGSESILFNKLESIAEQETPKTPVLGCGITYSLMKKN--LRANSFLPSRINWAIQSSGVDYLHLLCCSMEYIIKKYNLEARLCISIHDEIRFLVSEKDKYRAAMALQISNIWTRAMFCQQMGINELPQNCAFFSQVDIDSVIRKEVNMDCITPSNKTAIPHGEALDINQLLDKSNSKLGKPNLDIDSKVSQYAYNYREPVFEEYNKSYTPEFLKYFLAMQVQSDKRDVNRLEDEYLRECTSKEYARDGNTAEYSLLDYIKDVEKGKRTKVRIMGSNFLDGTKNAKADQRIRLPVNMPDYPTLHKIANDSAIPEKQLLENRRKKENRIDDENKKKLTRKKNTTPMERKYKRVYGGRKAFEAFYECANKPLDYTLETEKQFFNIPIDGVIDDVLNDKSNYKKKPSQARTASSSPIRKTAKAVHSKKLPARKSSTTNRNLVELERDITISREY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : :. . : : * : :* :...*: *:* . * . *: **: : : :.: ** * * .:::**: :.: : ** . * **. * * . * * *. :*****. . *.**.*:*.. ** * * . . :::****::***:: *:* ..: *:** *:*:. *: * **.: :: . *:: *: *.* :* .:: * * *::*.. : :.**.* :*** ** ** .:: *:: :: ***.::**: .:. . **.: * *: *: .:: *:: . : : : :: * : * :: ** : :* : :: .: :* : ***.* ***:* . . :: :: * *: * *:. *: :. ** : ** : :. . : ::*:** :* . . . ::*.: : ...*.: . :.::* *:* . :.** .*:** : . . . * *::*. **:****:* :*:****::.:*:****:: *:***** :*******:*****:::**: ** *.:*** *.* *..*:*:*: ** :* **:.**::**.****** **. ** :** :: .*: * ::: *** : . : : * **:** :**:**.** . *:**.** :: :* . *:.:*:**.:**..**:***: :*.::: . . *:*:*:***:*:** *: :**:*::*:*: **.: ::*:::** . **** *::* :*** .*** **** .: .: .: *. : . .:.. ", "identical_positions": 270, "similar_positions": 291, "identity": "17.69%" }, { "cls_id": "homologset.agr.SGD:S000005859", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PCU2-1", "uniprot_id": "VATE1_RAT", "id": "Q6PCU2-1", "name": "V-type proton ATPase subunit E 1", "aln": "-----MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKKEKQIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLVLQGLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKKD--VDVQIDLEAYLPEDIAGGVEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50518-1", "uniprot_id": "VATE1_MOUSE", "id": "P50518-1", "name": "V-type proton ATPase subunit E 1", "aln": "-----MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKKEKQIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLVLQGLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKKD--VDVQIDQEAYLPEEIAGGVEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36543-1", "uniprot_id": "VATE1_HUMAN", "id": "P36543-1", "name": "V-type proton ATPase subunit E 1", "aln": "-----MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKKEKQIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLVLQGLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKND--VDVQIDQESYLPEDIAGGVEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D593-1", "uniprot_id": "VATE2_MOUSE", "id": "Q9D593-1", "name": "V-type proton ATPase subunit E 2", "aln": "-----MALTDIDVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMDYFEKKEKQIEQQKKIQLSTMRNQARITVLRARDNLILELLKDAKMRLSRIVSDEEIYQDLLDKLVLQALLRLLEPVMIVRCRPQDLHLVESAVLRAIPQYMRLCQKH--LEVQVDQTEHLPSNAAGGVEVYSSDQKIKVSNTLESRLNLAAMQKMPEIRGILFGDNTSRKFFT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZJ78-1", "uniprot_id": "D3ZJ78_RAT", "id": "D3ZJ78-1", "name": "", "aln": "-----MALTDIDVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMDYFEKKEKQIEQQKKIQLSTMRNQARITVLRARDNLILELLKEAKMRLSRIVSDEEFYQDLLDKLVLQALLRLLEPVMIVRCREQDFYLVQSALLRAIPQYMMLCQKH--LEVQIDQTEYLSSNAAGGVEVYSSDRKIKVSNTLESRLNLAALQNMPEIRRTLFGDNSNRKFFT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96A05-1", "uniprot_id": "VATE2_HUMAN", "id": "Q96A05-1", "name": "V-type proton ATPase subunit E 2", "aln": "-----MALSDVDVKKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKKEKQIEQQKKILMSTMRNQARLKVLRARNDLISDLLSEAKLRLSRIVEDPEVYQGLLDKLVLQGLLRLLEPVMIVRCRPQDLLLVEAAVQKAIPEYMTISQKH--VEVQIDKEAYLAVNAAGGVEVYSGNQRIKVSNTLESRLDLSAKQKMPEIRMALFGANTNRKFFI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54611-1", "uniprot_id": "VATE_DROME", "id": "P54611-1", "name": "V-type proton ATPase subunit E", "aln": "-----MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQQQRLKIMEYYEKKEKQVELQKKIQSSNMLNQARLKVLKVREDHVSSVLDDARKRLGEVTKNQSEYETVLTKLIVQGLFQIMEPKVILRCREVDVPLVRNVLPAAVEQYKAQINQN--VELFIDEKDFLSADTCGGVELLALNGRIKVPNTLESRLDLISQQLVPEIRNALFGRNVNRKFTD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22203-1", "uniprot_id": "VATE_YEAST", "id": "P22203-1", "name": "V-type proton ATPase subunit E", "aln": "MSSAITALTPNQVNDELNKMQAFIRKEAEEKAKEIQLKADQEYEIEKTNIVRNETNNIDGNFKSKLKKAMLSQQITKSTIANKMRLKVLSAREQSLDGIFEETKEKLSGIANNRDEYKPILQSLIVEALLKLLEPKAIVKALERDVDLIESMKDDIMREYGEKAQRAPLEEIVISNDYLNKDLVSGGVVVSNASDKIEINNTLEERLKLLSEEALPAIRLELYGPSKTRKFFD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: :*:.::::* ***.:**:***:**: **::*::*** .:*: : :* ::.* *: .::* *.: *: *:.** .*:: : ::.::: :*. :..: *: :* *:::.* :::** *::. *. *:. : * :. :: :. .*** : . :*:: ****.**.* : : :* :* *:* . .*** ", "identical_positions": 60, "similar_positions": 87, "identity": "25.75%" }, { "cls_id": "homologset.agr.SGD:S000005861", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ET09-1", "uniprot_id": "MRS2_RAT", "id": "Q9ET09-1", "name": "Magnesium transporter MRS2 homolog, mitochondrial", "aln": "MECLRYLPRLLPRAAQ-SRSALCMAAVRLS-----LAACCGRATPLT-SGSQK--APSTPRTAGDVYRFRTSDASQATLASVAQVFAVTKFDKEGNVTSFERK--KTELYHELALQARDLR------FQHVMSITTRNNRIIMRMEYLKAVITPEYLLILDYRNLNLEHWLFRELPSQLAGEGQLVTYPLPFEFRAIEALLQYWINTLQGKLSILQPLILETLDALVDPKHSSVDRSKLHVLLQNGKSLSELETDIKIFKESILELLDEEEMLEELCLTKWSDPHVFEQSSTGIDHAEEMELLLENYYRLADDLSNEARELRVLIDDSQSIIFINLDSHRNVMMRLNLQLTMGTFSLSLFGLMGVAFGMNLESSLEEDHR------VFWLITGIMFMGSGLIWRRLLSFLGRQLEAPL-----PPVMASLPKKTLLADRRMDVKNSLRPEGLGAGRTILASR-------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5NCE8-1", "uniprot_id": "MRS2_MOUSE", "id": "Q5NCE8-1", "name": "Magnesium transporter MRS2 homolog, mitochondrial", "aln": "MECLRCLPGLLPRAAQ-PRRALWTAVARLS-----LAACGGRATPLR-SRSPK--ASSTARAAGDVLRFRTSDASQATLASVAQVFAVTKFDKEGNVTSFERK--KTELYHELALQARDLR------FQHVMSITTRNNRIIMRMEYLKAVITPECLLILDYRNLNLEHWLFRELPSQLAGEGQLVTYPLPFEFRAIEALLQYWISTLRGRLSVLQPLILETLDALVDPKHSSVDRSKLHVLLQNGKSLSELETDIKIFKESILELLDEEEMLEELCLTKWSDPHVFEKSSTGIDHAEEMELLLENYYRLAEDLSNEARELRVLIDDSQSIIFINLDSHRNVMMRLNLQLTMGTFSLSLFGLMGVAFGMNLESSLEEDHR------VFWLVTGIMFMGSGLIWRRLLSFLGRQLEAPV-----PPVMTSLPKKTLLANRRMDVKNSLRPEGLGASRTILASR-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HD23-1", "uniprot_id": "MRS2_HUMAN", "id": "Q9HD23-1", "name": "Magnesium transporter MRS2 homolog, mitochondrial", "aln": "MECLRSLPCLLPRAMRLPRRTLCALALDVTSVGPPVAACGRRANLIGRSRAAQLCGPDRLRVAGEVHRFRTSDVSQATLASVAPVFTVTKFDKQGNVTSFERK--KTELYQELGLQARDLR------FQHVMSITVRNNRIIMRMEYLKAVITPECLLILDYRNLNLEQWLFRELPSQLSGEGQLVTYPLPFEFRAIEALLQYWINTLQGKLSILQPLILETLDALVDPKHSSVDRSKLHILLQNGKSLSELETDIKIFKESILEILDEEELLEELCVSKWSDPQVFEKSSAGIDHAEEMELLLENYYRLADDLSNAARELRVLIDDSQSIIFINLDSHRNVMMRLNLQLTMGTFSLSLFGLMGVAFGMNLESSLEEDHR------IFWLITGIMFMGSGLIWRRLLSFLGRQLEAPL-----PPMMASLPKKTLLADRSMELKNSLRLDGLGSGRSILTNR-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q01926-1", "uniprot_id": "MRS2_YEAST", "id": "Q01926-1", "name": "Magnesium transporter MRS2, mitochondrial", "aln": "-----MNRRLLVRSIS-----CFQPLSRIT--------FGRPNTPFLRKYADT----STAANTNSTILRKQLLSLKPISASDSLFISCTVFNSKGNIISMSEKFPKWSFLTEHSLFPRDLRKIDNSSIDIIPTIMCKPNCIVINLLHIKALIERDKVYVFDTTNPSAAAKLSVLMYDLESKLSSTKNNSQFYEHRALESIFINVMSALETDFKLHSQICIQILNDLEN----EVNRLKLRHLLIKSKDLTLFYQKTLLIRDLLDELLENDDDLANMYLTVKKSP---------KDNFSDLEMLIETYYTQCDEYVQQSESLIQDIKSTEEIVNIILDANRNSLMLLELKVTIYTLGFTVASVLPAFYGMNLKNFIEESEWGFTSVAVFSIVSALYITKKNFNSLRSVTKMTMYPNSPANSSVYPKTSASIALTNKLKRRRKWWKSTKQRLGVLLYGSSYTNKANLSNNKINKGFSKVKKFNMENDIKNKQNRDMIWKWLIEDKKN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** *: :: . : . : . :... : :. ** : .:: * *:.:**: *:..* * .: * .* .**** :: : :* : * *::.: ::**:* : : ::* * . * : . : .. . . :*.**:*::: :.:*. :.: . : :: *: * : .*:* **: ** :.*.*: : . :::: : *:*:::: * :: :: ..* *: .::*:*:*.** .:: : :..* *..::.*: * **::** :* *:*::*: *:.::: .:: . :****:. :**.. :* :::.: : ..: * :: : ::* * :*:. .. * * *.: : *: : :.: ", "identical_positions": 80, "similar_positions": 168, "identity": "15.84%" }, { "cls_id": "homologset.agr.SGD:S000005862", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZX08-1", "uniprot_id": "SYAM_RAT", "id": "D3ZX08-1", "name": "Alanine--tRNA ligase, mitochondrial", "aln": "MAASVAAAAGR-----LRRAIGRSCPWQ-----RFSTEPHPPHGAAVRDAFLSFFRDRHGHRLVPSASVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSEMAGFRRVANSQKCVRAGGRHNDLEDVGRDLSHHTFFEMLGNWAFGGEYFKKEACSMAWELLTQVYGIPEDRLWVSYFSGDSKTGLDPDLETRDIWLSLGVPASRVLSFGLQENFWEMGDTGPCGPCTEIHYDLAGG------------MGPPQLVELWNLVFMQHYREADGSLHLLPQQHVDTGMGLERLVAVLQGKHSTYDTDLFSPLLDAIHQSCRVPPYSGRVGAA-DEGRIDTAYRVVADHIRTLSVCIADGVSPGMSGAPLVLRRILRRAVRYSTEVLQAPPG-FLGNLVPVVVATLGAAYPELQKNSVKVLIWEIANLVSEDEAAFLASLQRGRRIIDR--------------------------TVKRLGP-SDLFPAEVAWSLSLSGNLGIPLDLVQLMLEEKGVKLDTAGLEQLAQKEAQHRAQQAEAAQE-----EGLCLDVHALEELHRQGIPTTDDSPKYNYSLRPN---GDYEFGLCEAQVLQLYSETGTAVASVGE------GQRCGLLLDRTNFYAEQGGQASDRG-YLIRTGQQ---DVLFPVARAQVCGGFILHEAMAP-----ECLQVGDRVQLYVDKAWRMGCMVKHTATHLLNWALRQTLGPTTEQRGSHLNPERLRFDVATQ-TPLTTEQLRTVESYVQEAVGQDKPVYMEEVPLAHTARIPGLR-SLDEVYPDP-VRVVSVGVPVAQALA-PASQAALQTSVELCCGTHLLSTGAVGDLVIIGDRQLVKGITRLLAITGEQAQQAREVGQSLSQEVEVASERLSRG-SRDLLEAHRLSKDIGRLIEFTESAVIPQWQRQEQQTTLKMLQRRANTAIRKLEKS---QATEKSQELLKRHSEGPLIVDTVSAQSLSVLVKVVRQLCKQA---PSMSVLLLSPQ-PTGSVLCACQVAQ-GATPTFTAEAWALAVCSHMGGKAWGSPVIAQGTG---HTADLEAALRTARAYALNQL--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14CH7-1", "uniprot_id": "SYAM_MOUSE", "id": "Q14CH7-1", "name": "Alanine--tRNA ligase, mitochondrial", "aln": "MAVALAAAAGK-----LRRAIGRSCPWQ-----PFSTEPGPPHGAAVRDAFLSFFRDRHGHRLVPSATVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSEMAGFRRVVNSQKCVRAGGRHNDLEDVGRDLSHHTFFEMLGNWAFGGEYFKEEACSMAWELLTQVYGIPEDRLWVSYFSGDSQTGLDPDLETRDIWLSLGVPASRVLSFGPQENFWEMGDTGPCGPCTEIHYDLAGG------------VGSPQLVELWNLVFMQHYREADGSLQLLPQRHVDTGMGLERLVAVLQGKRSTYDTDLFSPLLDAIHQSCGAPPYSGRVGAA-DEGRIDTAYRVVADHIRTLSVCIADGVSPGMSGAPLVLRRILRRAVRYSTEVLQAPPG-FLGSLVPVVVETLGSAYPELEKNSVK-----IASLVSEDEAAFLASLQRGRRIIDR--------------------------TVKRLGP-SDLFPAEVAWSLSLSGNLGIPLDLVELMLEEKGVKLDTAGLEQLAQKEAQHRAQQAEADQE-----DRLCLDVHALEELHRQGIPTTDDSPKYNYTLHPN---GDYEFGLCEARVLQLYSETGTAVASVGA------GQRCGLLLDRTNFYAEQGGQASDRG-YLVRTGQQ---DMLFPVAGAQLCGGFILHEAMAP-----ERLQVGDQVQLYVDKAWRMGCMVKHTATHLLSWALRQTLGPTTEQRGSHLNPERLRFDVATQ-TLLTTEQLRTVESYVQEVVGQDKPVFMEEVPLAHTARIPGLR-SLDEVYPDP-VRVVSVGVPVAHALG-PASQAAMHTSVELCCGTHLLSTGAVGDLVIIGERQLVKGITRLLAITGEQAQQAREVGQSLSQEVEAASERLSQG-SRDLPEAHRLSKDIGRLTEVAESAVIPQWQRQELQTTLKMLQRRANTAIRKLEKG---QATEKSQELLKRHSEGPLIVDTVSAESLSVLVKVVRQLCKQA---PSISVLLLSPQ-PTGSVLCACQVAQ-DATPTFTAEAWALAVCSHMGGKAWGSRVVAQGTG---HTADLEAALGTARAYALSQL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JTZ9-1", "uniprot_id": "SYAM_HUMAN", "id": "Q5JTZ9-1", "name": "Alanine--tRNA ligase, mitochondrial", "aln": "MAASVAAAARR-----LRRAIRRSPAWRGLSHRPLSSEPPAAKASAVRAAFLNFFRDRHGHRLVPSASVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSEMAGFRRVANSQKCVRAGGHHNDLEDVGRDLSHHTFFEMLGNWAFGGEYFKEEACNMAWELLTQVYGIPEERLWISYFDGDPKAGLDPDLETRDIWLSLGVPASRVLSFGPQENFWEMGDTGPCGPCTEIHYDLAGG------------VGAPQLVELWNLVFMQHNREADGSLQPLPQRHVDTGMGLERLVAVLQGKHSTYDTDLFSPLLNAIQQGCRAPPYLGRVGVA-DEGRTDTAYRVVADHIRTLSVCISDGIFPGMSGPPLVLRRILRRAVRFSMEILKAPPG-FLGSLVPVVVETLGDAYPELQRNSAQ-----IANLVSEDEAAFLASLERGRRIIDR--------------------------TLRTLGP-SDMFPAEVAWSLSLCGDLGLPLDMVELMLEEKGVQLDSAGLERLAQEEAQHRARQAEPVQK-----QGLWLDVHALGELQRQGVPPTDDSPKYNYSLRPS---GSYEFGTCEAQVLQLYTEDGTAVASVGK------GQRCGLLLDRTNFYAEQGGQASDRG-YLVRAGQE---DVLFPVARAQVCGGFILHEAVAP-----ECLRLGDQVQLHVDEAWRLGCMAKHTATHLLNWALRQTLGPGTEQQGSHLNPEQLRLDVTTQ-TPLTPEQLRAVENTVQEAVGQDEAVYMEEVPLALTAQVPGLR-SLDEVYPDP-VRVVSVGVPVAHALD-PASQAALQTSVELCCGTHLLRTGAVGDLVIIGDRQLSKGTTRLLAVTGEQAQQARELGQSLAQEVKAATERLSLG-SRDVAEALRLSKDIGRLIEAVETAVMPQWQRRELLATVKMLQRRANTAIRKLQMG---QAAKKTQELLERHSKGPLIVDTVSAESLSVLVKVVRQLCEQA---PSTSVLLLSPQ-PMGKVLCACQVAQ-GAMPTFTAEAWALAVCSHMGGKAWGSRVVAQGTG---STTDLEAALSIAQTYALSQL--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q6V5-1", "uniprot_id": "A0A8M1Q6V5_DANRE", "id": "A0A8M1Q6V5-1", "name": "Alanine--tRNA ligase", "aln": "MAARITVVKHVHCALLITKLSCLSSGIRRCTALSFSVYRREFTSKRVRRKFIDFFREGYGHRVVPSSSVRPRGDPSLLFVNAGMNQFKPILLGCADPRSEMVSYRRVVNSQKCVRAGGKHNDLQDVGKDVYHHTFFEMLGNWSFG-DYFKVEACAMAWRLLTEEYGIPAQRLYVSYFSGDPANGLPADEETRDIWLSMGLRADHVLPFGMKDNFWEMGETGPCGPCTEIHYDHIGNR----NAALLVNADSPDVVEIWNLVFMQYNRESNGSLRALPQCSVDTGMGLERLVTVLQGKRSNYDTDLFTPLLSAIHQCSKAPAYQGRTGAA-DVAQLDMAYRVVADHIRTICVCIADGVYPGMAGAELVLRRILRRAVRFSTEVLQAPEG-ALASLVPTVAHLLGDAYPELNTESDR-----IMDLINQNEAHFLSSLKQGRRVIDR--------------------------TLSNMDENSSFFPASVAWSLYR--NLGFPLDLIDLMLEEKGKIVDKKEMKVLEDEYEKLGLQSEEDEGE-----KLDQLDLHSLAELQRQRVPHTDDSPKYCYSVGSD---GQYVFEPCKASVLALYCD-GALVSEVRQ------GQHCAVILDQTSFYAEQGGQANDQG-YFTKDGLQ---DVLFPVKCVRLAGGYVVHKVTAA-----ETLRTGDQVHLHVDEAWRLGCMINHTATHVLNFALRELLGPIVSQRGSHCSANRLRFDFSVK-GTLTVSELQKVEELVLNIIRQNADVHVEEVPLSSAKQIAGLR-TVDELYPDP-VRVVSVAVPVSDLL---ASERAEQTSVELCCGTHLLRTGAIRDFVVVSERQMMKGVCRIVAFTGDDAIKAREAGQALQEELESLEARMGLSNTLSIQEAKRLSKEVGHLINAVDITPMPQWKRLELQTRLKAMLKSSNNSIRKLEIK---EAALKAKELLDKHSNKPVVVDLIQTDSISVLMKTVVQLSKST---PKSLVMLFSHWESSGKLLCACLVPK-GSTGG-SAIEWALSVCSRLGGNAEGAKDTAKGVGNAVKVEDVAEILHWAEEFAHNKIRNVPRTD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BGQ7-1", "uniprot_id": "SYAC_MOUSE", "id": "Q8BGQ7-1", "name": "Alanine--tRNA ligase, cytoplasmic", "aln": "-------------------------------------MDATLTAREIRERFINFFRRNE-HTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTIDPSHPMAKLSRAANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGSWSFG-DYFKELACKMALELLTQEFGIPVERLYVTYFGGDEAAGLEPDLECRQIWQNLGLDEARILPGNMKDNFWEMGDTGPCGPCSEIHYDRIGGR----DAAHLVNQDDPNVLEIWNLVFIQYNRESDGVLKPLPKKSIDTGMGLERLVSVLQNKMSNYDTDLFMPYFEAIQKGTGARPYTGKVGAE-DADGIDMAYRVLADHARTITVALADGGRPDNTGRGYVLRRILRRAVRYSHEKLNASRG-FFATLVDVVVQSLGDAFPELKKDPEM-----VKDIINEEEVQFLKTLSRGRRILDR--------------------------KIQSLGD-CKTIPGDTAWLLYD--TYGFPVDLTGLIAEEKGLVVDMNGFEEERRLAQLKSQGKGAGDE------DLIMLDIYAIEELRAKGLEATDDSPKYNYQSDSS---GSYVFECTVATVLALRREKMFVDEVVT-------GQECGVVLDKTCFYAEQGGQIYDEG-YLVKVDDSSEDKTEFTVKNAQVRGGYVLHIGTIY-----GNLKVGDQVRLFIDEPRRRPVMSNHTATHILNFALRSVLG-EADQKGSLVAPDRLRFDFTAK-GAMSTQQIKKAEEIVNGMIEAAKPVYTQDCPLAAAKAIQGLRAVFDETYPDP-VRVVSIGVPVSELLDDPCGPAGSLTSVEFCGGTHLRNSSHAGAFVIVTEEAIAKGIRRIVAVTGAEAQKALRKSETLKKSLSAMEAKVKAQ--TAP--NKDVQREIADLGEALATAVIPQWQKDEQRETLKSLKKVMDDLDRASKADVQKRVLEKTKQLIDSNPNQPLVILEMESGASAKALNEALKLFKTH--SPQTSAMLFTVDNEAGKITCLCQVPQNAANRGLKASEWVQQVSGLMDGKGGGKDMSAQATGK--NVGCLQEALQLATSFAQLRLGDVKN---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50475-1", "uniprot_id": "SYAC_RAT", "id": "P50475-1", "name": "Alanine--tRNA ligase, cytoplasmic", "aln": "-------------------------------------MDSTLTAREIRERFINYFKRNE-HTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTVDPSHPMAKLSRAANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGSWSFG-DYFKELACKMALELLTQEFGIPVERLYVTYFGGDEAAGLEPDLECRQIWQNLGLDEAKILPGNMKDNFWEMGDTGPCGPCSEIHYDRIGGR----DAAHLVNQDDPNVLEIWNLVFIQYNRESDGVLKPLPKKSIDTGMGLERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTGKVGAE-DTDGIDMAYRVLADHARTITVALADGGRPDNTGRGYVLRRILRRAVRYSHEKLNASRG-FFATLVDVVVQSLGDAFPELKKDPDM-----VKDIINEEEVQFLKTLSRGRRILDR--------------------------KIQSLGD-CQTIPGDTAWLLYD--TYGFPVDLTGLIAEEKGLVVDMDGFEEERKLAQLKSQGKGAGGE------DLIMLDIYAIEELRAKGLEATDDSPKYNYHSDSS---GSYVFECTVATVLALRREKMFVDEVVT-------GQECGVVLDKTCFYAEQGGQIFDEG-YLVKVDDSSEDKTEFTVKNAQVRGGYVLHIGTIY-----GNLRVGDQVRLFIDEPRRRPVMSNHTATHILNFALRSVLG-DADQKGSLVAPDRLRFDFTAK-GAMSTEQIKKTEEIVNGMIEAAKPVYTLDCPLAAAKAIQGLRAVFDETYPDP-VRVVSIGVPVSELLDDPSGPAGSLTSVEFCGGTHLRNSSHAGAFVIVTEEAIAKGIRRIVAVTGAEAQKALRKSETLKKSLSAMEVKVKAQ--SAP--NKDVQKEIADLGEVLATAVIPQWQKDEQRETLKSLKKVMDDLDRASKADVQKRVLEKTKQLIDSNPNQPLVILEMESGASAKALNEALKLFKTH--SPQTSAMLFTVDNEAGKITCLCQVPQNAANRGLKASEWVQQVSGLMDGKGGGKDMSAQATGK--NVGCLQEALQLATSFAQLRLGDVKN---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49588-1", "uniprot_id": "SYAC_HUMAN", "id": "P49588-1", "name": "Alanine--tRNA ligase, cytoplasmic", "aln": "-------------------------------------MDSTLTASEIRQRFIDFFKRNE-HTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTIDPSHPMAKLSRAANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGSWSFG-DYFKELACKMALELLTQEFGIPIERLYVTYFGGDEAAGLEADLECKQIWQNLGLDDTKILPGNMKDNFWEMGDTGPCGPCSEIHYDRIGGR----DAAHLVNQDDPNVLEIWNLVFIQYNREADGILKPLPKKSIDTGMGLERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTGKVGAE-DADGIDMAYRVLADHARTITVALADGGRPDNTGRGYVLRRILRRAVRYAHEKLNASRG-FFATLVDVVVQSLGDAFPELKKDPDM-----VKDIINEEEVQFLKTLSRGRRILDR--------------------------KIQSLGD-SKTIPGDTAWLLYD--TYGFPVDLTGLIAEEKGLVVDMDGFEEERKLAQLKSQGKGAGGE------DLIMLDIYAIEELRARGLEVTDDSPKYNYHLDSS---GSYVFENTVATVMALRREKMFVEEVST-------GQECGVVLDKTCFYAEQGGQIYDEG-YLVKVDDSSEDKTEFTVKNAQVRGGYVLHIGTIY-----GDLKVGDQVWLFIDEPRRRPIMSNHTATHILNFALRSVLG-EADQKGSLVAPDRLRFDFTAK-GAMSTQQIKKAEEIANEMIEAAKAVYTQDCPLAAAKAIQGLRAVFDETYPDP-VRVVSIGVPVSELLDDPSGPAGSLTSVEFCGGTHLRNSSHAGAFVIVTEEAIAKGIRRIVAVTGAEAQKALRKAESLKKCLSVMEAKVKAQ--TAP--NKDVQREIADLGEALATAVIPQWQKDELRETLKSLKKVMDDLDRASKADVQKRVLEKTKQFIDSNPNQPLVILEMESGASAKALNEALKLFKMH--SPQTSAMLFTVDNEAGKITCLCQVPQNAANRGLKASEWVQQVSGLMDGKGGGKDVSAQATGK--NVGCLQEALQLATSFAQLRLGDVKN---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLM8-1", "uniprot_id": "SYAC_DROME", "id": "Q9VLM8-1", "name": "Alanine--tRNA ligase, cytoplasmic", "aln": "--------------------------------------MKLLTAKEVRNAYLDFFKEQK-HIYVHSSSTIPLDDPTLLFANAGMNQFKPIFLGTADPNSEMSKWVRVANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGNWSFG-DYFKKEICSWAWEFLTQRLALPKDRLYVTYFGGDAASGLEPDLECKQMWLDLGLKPEHILPGSMKDNFWEMGETGPCGPCSELHFDRIGGR----SVPELVNMDDPDVLEIWNLVFIQYNRESDGSLKQLPKKHIDCGMGFERLVSVIQNKRSNYDTDLFVPLFDAIQAGTGAPPYQGRVGAD-DVDGIDMAYRVLADHARTITIALADGGTPDNTGRGYVLRRILRRAVRYATEKLNAKPG-FFATLVNTVVDLLGDAFPEVKKDPQH-----IIDIINEEELQFLKTLTRGRNLLNR--------------------------TIEKLGN-QTTIPGDVAWRLYD--TYGFPVDLTQLMAEEKSLKIDMDGYEAAKHNSYVLSQGKGASKI------EEINLDVHAISQLQEQGVPPTNDTFKYKYEAVSDERDSAYNYGVCNSKIVALRFENQFVNEITS-------GQKAGIVLDKTNFYAESGGQIYDQG-ALVKVNDEAN---EFLVDRVYNRGGYILHIGVVE-----GTLKVGDELELHIDVERRWLTMKNHSATHALNHCLLQVLGKDTEQKGSLVVPEKLRFDFNSK-AAMTIEQVSKTEQLTKEMVYKNVPIYAKESKLALAKKIRGLRSVFDEVYPDP-VRVISFGVPVDELEQNPDSEAGEQTSVEFCGGTHLRRSGHIMDFVISSEEAIAKGIRRIVALTGPEALKALKKSEAFEQEIVRLKATIDND--KSGKDSKSHVKEIVELTEQISHATIPYVKKDEMRNLLKGLKKTLDDKERALRAAVSVTVVERAKTLCEANPNATVLVEQLEAFNNTKALDAALKQVRSQ--LPDAAAMFLSVDADSKKIFCLSSVPKSAVEKGLKANEWVQHVSATLGGKGGGKPESAQASGT--NYEKVDEIVQLASKFAQSKLS-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40825-1", "uniprot_id": "SYA_YEAST", "id": "P40825-1", "name": "Alanine--tRNA ligase, mitochondrial", "aln": "MTSTTGLRNLT-----LSFKKQLTTSTR---TIMTIGDKQKWTATNVRNTFLDYFKSKE-HKFVKSSPVVPFDDPTLLFANAGMNQYKPIFLGTVDPASDFYTLKRAYNSQKCIRAGGKHNDLEDVGKDSYHHTFFEMLGNWSFG-DYFKKEAITYSWTLLTEVYGIPKDRLYVTYFEGDEKLGLEPDTEARELWKNVGVPDDHILPGNAKDNFWEMGDQGPCGPCSEIHYDRIGGR----NAASLVNMDDPDVLEVWNLVFIQFNREQDGSLKPLPAKHIDTGMGFERLVSVLQDVRSNYDTDVFTPLFERIQEITSVRPYSGNFGEN-DKDGIDTAYRVLADHVRTLTFALADGGVPNNEGRGYVLRRILRRGARYARKYMNYPIGNFFSTLAPTLISQVQDIFPELAKDPAF-----LFEILDEEEASFAKTLDRGERLFEKY------------------------ASAASKTE-SKTLDGKQVWRLYD--TYGFPVDLTELMAEEQGLKIDGPGFEKAKQESYEASKRGGKKDQS-----DLIKLNVHELSELNDAKVPKTNDEFKYGSANVEG-------------TILKLHDGTNFVDEITEP------GKKYGIILDKTCFYAEQGGQEYDTG-KIVIDD-----AAEFNVENVQLYNGFVFHTGSLEE----GKLSVGDKIIASFDELRRFPIKNNHTGTHILNFALKETLGNDVDQKGSLVAPEKLRFDFSHK-KAVSNEELKKVEDICNEQIKENLQVFYKEIPLDLAKSIDGVRAVFGETYPDP-VRVVSVGKPIEELLANPANEEWTKYSIEFCGGTHVNKTGDIKYFVILEESGIAKGIRRIVAVTGTEAFEAQRLAEQFAADLDAADKLPFSP--IKE-------KKLKELGVKLGQLSISVITKNELKQKFNKIEKAVKDEVKSRAKKENKQTLDEVKTFFETNENAPYLVKFIDISPNAKAITEAINYMKSNDSVKDKSIYLLAGNDPEGRVAHGCYISNAALAKGIDGSALAKKVSSIIGGKAGGKGNVFQGMGD--KPAAIKDAVDDLESLFKEKLSI------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VRJ1-1", "uniprot_id": "SYAM_DROME", "id": "Q9VRJ1-1", "name": "Alanine--tRNA ligase, mitochondrial", "aln": "------------------------------MYNSAKQLQRVLTAREIRKTFLDHFTVNHGHKFVRSSPVVPFCDPTVAFVNAGMNQFKSVFLGTAAAP-----HKRVVNSQKCVRVGGKHNDLSVVGTDGYHHTFFEMLGNWSFG-DYFKREACAMALELLRGPYNIDPGRLYVTYFAGDKVLGIPADLECFEIWRSLGFPASRILPFGCADNFWEMGATGPCGPCTEIHIDHRPDLGSVEQRAKLVNAGRSDLTELWNLVFIQYNRHADGSISQLPAHHVDTGMGFERLTAVLQNKSSNYDTDLFTPIFDGIQQAAKTPVYSGSFPDGGNAAVLDTSYRILADHARMVTACLADGMLPDQNQK---LRRVLRKALNISEHVFAHDKL--LTQLVPIVVETLGEAYPEMAAKQQA-----VIDLICHEQEVYKNLRESSSKAFAEVLMEFPNLDDIDLMECPGFVPAYRELQMQRCKFSNNTIPGDFLYKLTD--TYGLTEESFLKLAELENMNCDLERYRAEVSLAKLKAKGNQRETAGGSLCDLATEQRIAEAQAMLTKRLTPTDNSHKYTYSFDKE--SDSYQIPPLKTRVLGMLLNDAEVSRTQGSRIQQPFTDLISIVTAGSNFYYESGGQQSDGGKILVSNHQQPDHPHSLDVIGVKHLNDCVVHICKLSSPTDAFQLAIGDEVELQVDAQQRQLNTCHHTATHLLNAAIRSLFKKVTYQVSSSVSSDQCKLELGLLGKRIQKTDVQLIEDLINRVICSAAPVEVQLLSAAEVLEQNDITMVPGEVYPEQGLRLVNVES-----------PELQLSSKELCCGTHATNTSELSCFCIVNLKQTNRARFAFTAVAGQAAENVLKTAALLRHRVDLLEKQFQTD---KLTNATEAELQTIRHNMLHTDIKLPYAFKMDTLERITEMLKRIKDS-SRTTLKEFVDVEMRTLLQEKPLDTHPFILHYITSSALVEEIPLQRATKLCP------DRPILVISVCDSVVKARCCVPEKCITEKFNASAWLQSFADTFNGQIAAPKGQNPQAVCNMKGRRVSNLFEEQLEQAMSKAHAYAKLYL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* ::..* * * *:.. * **:: *.******:*.::*. . *. *:***:*.**:****. ** * *********.*:** :*** : :* : **:::** ** *: .* * ::* .:*. ::*. . :****** ******:*:* * . . .:: *:*****:*. *. :* : ** :* ***:***.:*:*. *.****:* * :. *: . * * : * :**::*** * : .::** *. ***:**:. . : . : : *. : : :**: . : .:: .:: : . . : . : .. : * *:. : : * :. * . : : : *:: ** :: : . .:: : ** *.*** * * : : * . .. :.* * **.: .* * :*:.** *. .: . : . * .* .:: :::. : :: *. : : . .: .* **: :*::.. * *:* *** :. : : :. : *.:* * :. . . : : . :. : : .. : : . . . . . :: : : :: : . :.: . .. :.*: . : . : ", "identical_positions": 166, "similar_positions": 224, "identity": "15.33%" }, { "cls_id": "homologset.agr.SGD:S000005863", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLA3-1", "uniprot_id": "UGGG1_RAT", "id": "Q9JLA3-1", "name": "UDP-glucose:glycoprotein glucosyltransferase 1", "aln": "MCSRGDANAAGAAAARRVTGLCYNMGLLIALALLC-LFSLAEANSKAITTSLTTKWFSAPLLLEASEFLAEDSQEKFWSFVEASQNIGSS-DQHDTDRSYYDAILEAAFRFLSPLQQNLLKFCLSLRSYSASIQAFQQIAVDEPPPEGCK--SFLSVHGKQTCDLGTLESLLLTAPDRP----KPLLFKGDHRYP-SSNPESPVVIFY--SEIGHEEFSNIHHQLISKSN--EGKINYVFRHYISNPRKEPVHLSGYGVELAIKSTEYKAKDDTQVKG-TEVNTTVIGENDPIDEVQGFLFGKLRELYPSLEGQLKEFRKHLVESTNEMAPLKVWQLQDLSFQTAARILAAPVELALVVMKDISQNFPTKARAITKTAVSAQLRAEVEENQKYFKGTIGLQPGDSALFINGLHIDLDTQDIFSLFDTLRNEARVMEGLHRLGIEGLSLHNILKLN-IQPSETDYAVDIRS----------------PAISWVNNLEVDSRYNSWPSSLQELLRPTFPGVIRQIRKNLHNMVFIVDPVHETTAELVSIAEMFLSNHIPLRIGFIFVVNDSEDVDGMQDAGVAVLRAYNYVGQEVDGYHAFQTLTQIYN-KVRT-GEKVKVEHVVSVLEKKYP---YVEVNSILGIDSAYDQNRKEARGYYEQTGVG--PLPVVLFNGMPFEKEQLDPD-ELETITMHKILETTTFFQRAVYLGELSHDQDVVEYIMNQPNVVPRINSRILTAK-REYLDLTAS-NNFYVDDFARFSALDSRGKTAAIANSMNYLTKKGMSSKEIYDDSFIRPVTFWIVGDFDSPSGRQLLYDAIKHQKTSNNV-RISMINNPSREISDSSTPVSRAIWAALQTQTSNSAKNFITKMVKEETAEALAAGVDIGEFSVGGMDVSLFKEVFESSRMDFILSHALYCRDVLKLKKGQRVVISNGRIIGPLEDS----ELFNQDDFHLLENIILKTSGQKIKSHIQQ---LRVEEDVASDLVMKVDALLSAQPKGEARIEYQFFEDKHSAIKLKPK-EGETYYDVVAVVDPVTREAQRLAPLLLVLAQLINMSLRVFMNCQSKLSDMPLKSFYRYVLEPEISFTADNSFAKGPIAKFLDMPQSPLFTLNLNTPESWMVESVRTPYDLDNIYLEEVDSIVAAEYELEYLLLEGHCYDITTGQPPRGLQFTLGTSANPTTVDTIVMANLGYFQLKANPGAWILRLRKGRSDDIYRIYSHDGTDSPPDAN--DVVVILNNFKSKIIKVKVQKKADMANEDLLSDG-TNENESGFWDSFKWGFSG-QKTEE------VKQDKDDIINIFSVASG--HLYERFLRIMMLSVLKNTKTP-VKFWFLKN-YLSPTFKEFIPYMAKKYNFQ--YELVQYKWPRWLHQQTEKQRIIWGYKILFLDVLFPLVVDKFLFVDADQIVRTDLKELRDFNLDGAPYGYTPFCDSRREMDGYRFWKSGYWASHLAG---RKYHISALYVVDLKKFRKIAAGDRLRGQYQGLSQDPNSLSNLDQDLPNNMIHQVPIKSLPQEWLWCETWCDDASKKRAKTIDLCNNPMTKEPKLEAAVRIVPEWQDYDQEIKQLQTLFQEEKELGTLHEEETQE-------------GSQKHEEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P5E4-1", "uniprot_id": "UGGG1_MOUSE", "id": "Q6P5E4-1", "name": "UDP-glucose:glycoprotein glucosyltransferase 1", "aln": "MCSRGDANTADAAAARRVTGLRYNMRLLIALALPC-LFSLAEANSKAITTSLTTKWFSAPLLLEASEFLAEDSQEKFWSFVEATQNIGSS-DHHDTDHSYYDAVLEAAFRFLSPLQQNLLKFCLSLRSYSASIQAFQQIAVDEPPPEGCK--SFLSVHGKQTCDLDTLESLLLTAADRP----KPLLFKGDHRYP-SSNPESPVVILY--SEIGHEEFSNIHHQLISKSN--EGKINYVFRHYISNPSKEPVYLSGYGVELAIKSTEYKAKDDTQVKG-TEVNATVIGESDPIDEVQGFLFGKLRELYPALEGQLKEFRKHLVESTNEMAPLKVWQLQDLSFQTAARILAASGALSLVVMKDISQNFPTKARAITKTAVSAQLRAEVEENQKYFKGTIGLQPGDSALFINGLHIDLDTQDIFSLFDTLRNEARVMEGLHRLGIEGLSLHNILKLN-IQPSETDYAVDIRS----------------PAISWVNNLEVDSRYNSWPSSLQELLRPTFPGVIRQIRKNLHNMVFIIDPVHETTAELISIAEMFLSNHIPLRIGFIFVVNDSEDVDGMQDAGVAVLRAYNYVAQEVDGYHAFQTLTQIYN-KVRT-GETVKVEHVVSVLEKKYP---YVEVNSILGIDSAYDQNRKEARGYYEQTGVG--PLPVVLFNGMPFEKEQLDPD-ELETITMHKILETTTFFQRAVYLGELSHDQDVVEYIMNQPNVVPRINSRILTAK-REYLDLTAS-NNFYVDDFARFSALDSRGKTAAIANSMNYLTKKGMSSKEIYDDSFIRPVTFWIVGDFDSPSGRQLLYDAIKHQKTSNNV-RISMINNPSQEISDSSTPIFRAIWAALQTQASSSAKNFITKMAKEETAEALAAGVDIAEFSVGGMDVSLFKEVFESSRMDFILSHALYCRDVLKLKKGQRVVISNGRIIGPLEDN----ELFNQDDFHLLENIILKTSGQKIKSHIQQ---LRVEEDVASDLVMKVDALLSAQPKGEARIEYQFFEDKHSAIKLKPK-EGETYYDVVAVVDPVTREAQRLAPLLLVLTQLINMNLRVFMNCQSKLSDMPLKSFYRYVLEPEISFTADSSFAKGPIAKFLDMPQSPLFTLNLNTPESWMVESVRTPYDLDNIYLEEVDSIVAAEYELEYLLLEGHCYDITTGQPPRGLQFTLGTSANPTIVDTIVMANLGYFQLKANPGAWILRLRKGRSDDIYRIYSHDGTDSPPDAN--DVVVILNNFKSKIIKVKVQKKADMANEDLLSDG-TNENESGFWDSFKWGFSG-QKAEE------VKQDKDDIINIFSVASG--HLYERFLRIMMLSVLKNTKTP-VKFWFLKN-YLSPTFKEFIPYMAKKYNFQ--YELVQYKWPRWLHQQTEKQRIIWGYKILFLDVLFPLVVDKFLFVDADQIVRTDLKELRDFNLDGAPYGYTPFCDSRREMDGYRFWKSGYWASHLAG---RKYHISALYVVDLKKFRKIAAGDRLRGQYQGLSQDPNSLSNLDQDLPNNMIHQVPIKSLPQEWLWCETWCDDASKKRAKTIDLCNNPMTKEPKLEAAVRIVPEWQDYDQEIKQLQTLFQEEKELGTLHTEETQE-------------GSQKHEEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYU2-1", "uniprot_id": "UGGG1_HUMAN", "id": "Q9NYU2-1", "name": "UDP-glucose:glycoprotein glucosyltransferase 1", "aln": "MGCKGDASGACAAGALPVTGVCYKMGVLVVLTVLW-LFSSVKADSKAITTSLTTKWFSTPLLLEASEFLAEDSQEKFWNFVEASQNIGSS-DHDGTDYSYYHAILEAAFQFLSPLQQNLFKFCLSLRSYSATIQAFQQIAADEPPPEGCN--SFFSVHGKKTCESDTLEALLLTASERP----KPLLFKGDHRYP-SSNPESPVVIFY--SEIGSEEFSNFHRQLISKSN--AGKINYVFRHYIFNPRKEPVYLSGYGVELAIKSTEYKAKDDTQVKG-TEVNTTVIGENDPIDEVQGFLFGKLRDLHPDLEGQLKELRKHLVESTNEMAPLKVWQLQDLSFQTAARILASPVELALVVMKDLSQNFPTKARAITKTAVSSELRTEVEENQKYFKGTLGLQPGDSALFINGLHMDLDTQDIFSLFDVLRNEARVMEGLHRLGIEGLSLHNVLKLN-IQPSEADYAVDIRS----------------PAISWVNNLEVDSRYNSWPSSLQELLRPTFPGVIRQIRKNLHNMVFIVDPAHETTAELMNTAEMFLSNHIPLRIGFIFVVNDSEDVDGMQDAGVAVLRAYNYVAQEVDDYHAFQTLTHIYN-KVRT-GEKVKVEHVVSVLEKKYP---YVEVNSILGIDSAYDRNRKEARGYYEQTGVG--PLPVVLFNGMPFEREQLDPD-ELETITMHKILETTTFFQRAVYLGELPHDQDVVEYIMNQPNVVPRINSRILTAE-RDYLDLTAS-NNFFVDDYARFTILDSQGKTAAVANSMNYLTKKGMSSKEIYDDSFIRPVTFWIVGDFDSPSGRQLLYDAIKHQKSSNNV-RISMINNPAKEISYENTQISRAIWAALQTQTSNAAKNFITKMAKEGAAEALAAGADIAEFSVGGMDFSLFKEVFESSKMDFILSHAVYCRDVLKLKKGQRAVISNGRIIGPLEDS----ELFNQDDFHLLENIILKTSGQKIKSHIQQ---LRVEEDVASDLVMKVDALLSAQPKGDPRIEYQFFEDRHSAIKLRPK-EGETYFDVVAVVDPVTREAQRLAPLLLVLAQLINMNLRVFMNCQSKLSDMPLKSFYRYVLEPEISFTSDNSFAKGPIAKFLDMPQSPLFTLNLNTPESWMVESVRTPYDLDNIYLEEVDSVVAAEYELEYLLLEGHCYDITTGQPPRGLQFTLGTSANPVIVDTIVMANLGYFQLKANPGAWILRLRKGRSEDIYRIYSHDGTDSPPDAD--EVVIVLNNFKSKIIKVKVQKKADMVNEDLLSDG-TSENESGFWDSFKWGFTG-QKTEE------VKQDKDDIINIFSVASG--HLYERFLRIMMLSVLKNTKTP-VKFWFLKN-YLSPTFKEFIPYMANEYNFQ--YELVQYKWPRWLHQQTEKQRIIWGYKILFLDVLFPLVVDKFLFVDADQIVRTDLKELRDFNLDGAPYGYTPFCDSRREMDGYRFWKSGYWASHLAG---RKYHISALYVVDLKKFRKIAAGDRLRGQYQGLSQDPNSLSNLDQDLPNNMIHQVPIKSLPQEWLWCETWCDDASKKRAKTIDLCNNPMTKEPKLEAAVRIVPEWQDYDQEIKQLQIRFQKEKETGALYKEKTKEPSR---------EGPQKREEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QEQ5-1", "uniprot_id": "A0A8M9QEQ5_DANRE", "id": "A0A8M9QEQ5-1", "name": "UDP-glucose ceramide glucosyltransferase-like 1", "aln": "-------MATHEADSEAGVGFCGKMWLFCAALLALGSVDSVNGDSKAVTTTLTTKWPSTPLLLEASEFLAEESQDKFWAFVEANQNIEN--DHDDTDQAYYDLILKRAGELLSPVQLNLLKFSLSLRAYSSTIHSFQQIASNEPPPSGCK--AFFNVHGQKSCDSERLQGMLDNALERP----KPNLFKGDHRYH-SANPDAPVVILY--AEMGTKEFSRLHQLMLSKAN--KGMITYVLRHFLASPSKSKVHLSGYGVELAIKNQEYKAKDDTQVQAGADANATVIGENDPVDEVQGFLFGKLKTIYPELKEQLKELRKHLIESTNEMAPLKVWQMQDLSFQTAARILAAPSVDALNVMKDLSQNFPTKARSITKTVVNSEIRKEIEENQKYFKGTLGLQPGDSALFINGLHIDLDVQDIFSVFDVLRNEARVMEGLRSLLIETPYIHDILKLN-VQPSDSDYAVDIRN----------------PAVHWINNLETDGRYASWPSNVQELLRPTFPGVIRQIRKNFHNLVMILDPTHENTAELLGVAEMFYSNNIPLRIGVVFVVNDSDDVDGMQDPGVALLRAFNYIADDVDGQMAFDAVISIMN-RIPS-GDKLKVEHVVGVLEKRYP---YVEISSILGPDSAYDNNRKEGKAYYEQTGVG--PLPVVLYNGMPLQREQLDPD-ELETVVMHKILETTSFFQRTVYLGELNSDHDVVDYIMNQPNVVPRINSRILSTS-RNYLDLSAT-NNHFIDEYARFLFLDAKDKNAAVANSMNYMTKKGMSTRDASDDGIIRPVTFWVVGDFDQPSGRQLLYDAIRHMKTSNNV-RLGLINNPSENPSNENSLIARAIWAAMQTQTSNNAKNFITKMAKEETAQALYGGSDIAEFAVGGMDVPLFKSAYESPNVNFLLAHSAYCRDVLKLQKGQRAVISNGRIIGPLEER----EVFNQDDFLLLESIILKTSGERIKGKIQQ---MGMVEDRASDLVMKVDALLSSQPKGEARIEHTFAEDRYSAVKIRPK-EEEVYFDVVAVLDPVTRDAQKLAPLLLVLKQLVNVNLRVFMNCQSKLSDLPLKSFYRYVLEPEIVFLTDSSFAPGPMAKFLDMPQSPLFTLNLNTPESWMVESVHTRYDLDNIYLEEVDSVVAAEYELEYLLLEGHCFDVTTGQPPRGLQFTLGTASDPVIVDTIVMANLGYFQLKANPGAWMLRLRKGRSDDIYKIYSHDGTDSPAEAD--DLIVVLNNFKSKIIKVKVQKKPDMINEELLSDG-THENESGFWTSIARGFTGGSNPEE------PKQEKDDVINIFSVASG--HLYERFLRIMMLSVLKHTKTP-VKFWFLKN-YLSPTFKEFIPYMAEKYGFQ--YELVQYKWPRWLHQQTEKQRIIWGYKILFLDVLFPLAVDKFLFVDADQIVRTDLKELRDFDLEGAPYGYTPFCESRREMDGYRFWKSGYWASHLAG---RKYHISALYVVDLKKFRKIAAGDRLRGQYQGLSQDPNSLSNLDQDLPNNMIHQVPIKSLPQEWLWCETWCDDASKKKAKTIDLCNNPQTKEPKLQAAVRIVGEWSDYDQEIKRIYNNFLDEKERGTLEGYQSTDRKH---------PGGDTHSEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E9Q4X2-1", "uniprot_id": "E9Q4X2_MOUSE", "id": "E9Q4X2-1", "name": "UDP-glucose:glycoprotein glucosyltransferase 1", "aln": "----------------------MRLLLRSVALWLALLGASTATASKAVTAHLTAKWPETPLLLEASEFMAEESNEKFWQFVETVRELAVY-KQTESDYSYYNLILKKAGQFLDNIHINLLKFAFSIRAYSPTIQMFQQMAADEPPPEGCT--AFVVIHTKCTCKVNEIKKLLNKAVSRP----RPYLFERDHKFP-TSSDNLPVIVLY--AEIGTRAFAEFHRVLSKKSK--NGKILYVLRHYIQKPSSRKMYLSGYGVELAIKDTEYKALDDTQIKT---TTDTDIENETEVDEVQGFLFGKLKEIYSDLKDNLTIFQKYLIESSKEMTPLKVWELQDLSFQAATQIVSTPVYDAIKLMKDISQNFPVKARTLTRIAVNELMRKEIQENQKDLRDRFEIKPGDARLFINGLRVDVDVYDPFSILDMLKSEGKLLSGLKSLGLSEEERNRFLKLN-SPVWDHDFVLDIRH----------------SSIVWINDLENDGLYIDWPSSCWEFLKPVLHGTVPSVRRNFHNLVLFIDPAQEYTLDFINLAEFFYFNEIPLRIGFVFILNVDNEVDGTTDAGVALWRAFNYIEEKYDVSEAFISMTHMYQ-EVKG-HRILTVDEVKSILQNKCP---HADILDILGIHSKYDGRRMEGATFYKMTGLG--PLPQALYNGEPFDLKEMNTE-ELKGAVLEKMVGTFVDLQRDVFMGTIRDETSAIDFLMDKSNVVSRLNSLILQTE-PQYLNLLSSSVTADIEDFSTFSFLDSQDKSAVIAKHMHYVTQED---------AVISPVTLWIIADFDVPSGRKLLFNALKHMETSFHS-RLGIVYNPTSKINEESTVISRGILAAFLTHKNKHLRSFLRRLAEEETAEAIYSGDKVQTFLAVEMDKNAFEKKYNTVGVNIFRTHQLFCQDVLKLRPGEPGIISNGKFLGPLSDE------LYQEDFHLLEKITFSNSLQNIAGIVES---MDMNSKHMSDLVMKIDGLMSSLAVRASRYDVTLLKENLSVIKINPP-ENDTFFDVFAIVDPLTREAQKMAQFLVVLGKIVNARIKLFMNCRGKLSEAPLDSFYRFVLEPELTSGPNNRPSHGPVAKFLDIPESHLLTLNMITPEGWLVETVHSNCDLDNINLKDTERSVTAEYELEYLLLEGHCFDMTTEQPPQGLQFTLGTRSNPVVVDTIVMANLGYFQLKANPGAWILKLREGKSEDIYEITGHEGAEPETNVG--NVIVVLNTFKSKILKIQVKKKSGKIQEDVLAD--KHE-NRGMWDSIKSFTKSLHK---------DEKKENDILNIFSVASG--HLYERFLRIMMLSVLRNTETP-VKFWFLKN-YLSPTFKEVIPHMAKEYGFQ--YELVQYKWPHWLHQQTDKQRIIWGYKILFLDVLFPLAVDKVIFVDADQIVRHDLKELRDFDLGGAPYGYTPFCDSRTEMDGYRFWKTGYWASHLVK---RKYHISALYVVDLKKFRRISAGDRLRGQYQALSQDPNSLSNLDQDLPNNMIYQVAIKSLPQDWLWCETWCDDESKQRAKTIDLCNNPKTKEPKLEAAARIVPEWVTYDTEIRTLLDHLENKK-------KSANS----------------VHDEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYU1-1", "uniprot_id": "UGGG2_HUMAN", "id": "Q9NYU1-1", "name": "UDP-glucose:glycoprotein glucosyltransferase 2", "aln": "-------------MAPAKATNVVRLLLGSTALWLSQLGSGTVAASKSVTAHLAAKWPETPLLLEASEFMAEESNEKFWQFLETVQELAIY-KQTESDYSYYNLILKKAGQFLDNLHINLLKFAFSIRAYSPAIQMFQQIAADEPPPDGCN--AFVVIHKKHTCKINEIKKLLKKAASRT----RPYLFKGDHKFP-TNKENLPVVILY--AEMGTRTFSAFHKVLSEKAQ--NEEILYVLRHYIQKPSSRKMYLSGYGVELAIKSTEYKALDDTQVKT---VTNTTVEDETETNEVQGFLFGKLKEIYSDLRDNLTAFQKYLIESNKQMMPLKVWELQDLSFQAASQIMSAPVYDSIKLMKDISQNFPIKARSLTRIAVNQHMREEIKENQKDLQVRFKIQPGDARLFINGLRVDMDVYDAFSILDMLKLEGKMMNGLRNLGINGEDMSKFLKLN-SHIWEYTYVLDIRH----------------SSIMWINDLENDDLYITWPTSCQKLLKPVFPGSVPSIRRNFHNLVLFIDPAQEYTLDFIKLADVFYSHEVPLRIGFVFILNTDDEVDGANDAGVALWRAFNYIAEEFDISEAFISIVHMYQ-KVKKDQNILTVDNVKSVLQNTFP---HANIWDILGIHSKYDEERKAGASFYKMTGLG--PLPQALYNGEPFKHEEMNIK-ELKMAVLQRMMDASVYLQREVFLGTLNDRTNAIDFLMDRNNVVPRINTLILRTN-QQYLNLISTSVTADVEDFSTFFFLDSQDKSAVIAKNMYYLTQDDE--------SIISAVTLWIIADFDKPSGRKLLFNALKHMKTSVHS-RLGIIYNPTSKINEENTAISRGILAAFLTQKNMFLRSFLGQLAKEEIATAIYSGDKIKTFLIEGMDKNAFEKKYNTVGVNIFRTHQLFCQDVLKLRPGEMGIVSNGRFLGPLDED------FYAEDFYLLEKITFSNLGEKIKGIVEN---MGINANNMSDFIMKVDALMSSVPKRASRYDVTFLRENHSVIKTNPQ-ENDMFFNVIAIVDPLTREAQKMAQLLVVLGKIINMKIKLFMNCRGRLSEAPLESFYRFVLEPELMSGANDVSSLGPVAKFLDIPESPLLILNMITPEGWLVETVHSNCDLDNIHLKDTEKTVTAEYELEYLLLEGQCFDKVTEQPPRGLQFTLGTKNKPAVVDTIVMAHHGYFQLKANPGAWILRLHQGKSEDIYQIVGHEGTDSQADLE--DIIVVLNSFKSKILKVKVKKETDKIKEDILTD--EDEKTKGLWDSIKSFTVSLHK---------ENKKEKDVLNIFSVASG--HLYERFLRIMMLSVLRNTKTP-VKFWLLKN-YLSPTFKEVIPHMAKEYGFR--YELVQYRWPRWLRQQTERQRIIWGYKILFLDVLFPLAVDKIIFVDADQIVRHDLKELRDFDLDGAPYGYTPFCDSRREMDGYRFWKTGYWASHLLR---RKYHISALYVVDLKKFRRIGAGDRLRSQYQALSQDPNSLSNLDQDLPNNMIYQVAIKSLPQDWLWCETWCDDESKQRAKTIDLCNNPKTKESKLKAAARIVPEWVEYDAEIRQLLDHLENKK-------QDTIL----------------THDEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F6G9-1", "uniprot_id": "E7F6G9_DANRE", "id": "E7F6G9-1", "name": "UDP-glucose ceramide glucosyltransferase-like 1", "aln": "----------------------MRLVFVVLVFLRVQHVN---SASKGIVASLQAKWAATPLLLETSEFIREDGDEKFWQFVDTVKELTVY-KSGESVRSYYNLILKKAGQFLTDLQVNLLKLSLSLRTYSPAVHALQQIASDEPPPEGCS--AFVVVHGQNACSTKDMKKLLKTAADRP----RPYLYKSDHQYPGVNGTDVPVAILY--AEIGTKEFSTFHKVLSERAQ--EGKLIYVLRHFVSEPKNERMLLSGYGVELAIKSTEYKAVDDTKVKE---SKSAGTDNEDENDEVQGFLFGKLKKSHPELQEELGELRKHLLESTNDMTPLKVWELQDLSFQAASRIMTVPKFDSLKLMQELSQNFPSRARSLTRVAVNQDMKKEIEDNQKRLSESMGVHPGDASLYINGIHVDLDIHNPFSILDILRSEAKILEGLHNLGVKGSSISKFLHLPSSTTVEDSYALDIRH----------------SSIMWVNDIEKDSMYRHWPSSLQELLRATFPGVIRQIRRNFYNLVLFLDPAQEESIELVKLAELFYKHNIPLRIGFVLVVNSDDEVDGLSDAGVALFRLLNYISEEYDEAQAFTSMVSIFN-RIGV-GKTLSVDTIKAYLKKKFP---KANAARILGVDSSYDDNRKAGGTFYKKSGLG--ALPVGLFNGVPLSSEEMDPE-ELETVLLQKIMETTNFFQRSVFMGQITESVDVVDFLMEQANVVPRINPLILSSD-RRYLDFTASPVADDWDDSAMFLYLDSRDKTGVISKRMKYFIREEA--------EVLYGVTMWIVADIEQPSGRQLLRNALKHMKSSSSSCRVGVINNPNRKPTEENSALYRAVWASLLTQSSKNTLDFTLKLLKEENVELLKQGTKIKHLLKQGMDHDAFEKKFNTMEVDFLHSQQKYCREVLKLQAGQRAVVSNGRILGLLDDKDDNEEVFSVEDFHLLEMITLRTSAEKIKSKIKQ---MNFSAQKASDLIMKVDALLSSSPKGEARKDVKFLKDKHSVLHLAQR-EDEVFYDVVAIVDPLTREAQKLAPLLVVLGQVVNMKVQVFMNCRAKLSEMPLKSFYQYVLEPDVSFFGNNSLSPGPMARFTEIPESPLLTLNMITPESWMVEAVRSPYDLDNIHLQEVSGVVNAEYELEYLLLEGHCFDLSTGQPPRGLQFTLGMRQEPLMHDTIVMANLGYFQLKANPGAWILRLREGRSEDIYQIQAHDGTDSPVDAG--DVIVVLNSFHSKIIKVRVQKRPDKLNEDLLSE--GAE-SKGLWDSITSVWSSLEKSFSGGPSVDEGNNKKDVLNIFSVASG--HLYERFLRIMMLSVLRHTTTP-VKFWFLKN-YLSPSFKETISHMAKAYGFQ--YELVQYKWPRWLHQQTEKQRIIWGYKILFLDVLFPLAVDKIIFVDADQIVRADLKELRDLDLEGAPYGYTPFCDSRKEMEGYRFWKTGYWASHLGH---RRYHISALYVVDLKKFRKIAAGDRLRGQYQALSQDPNSLSNLDQDLPNNMIHQVAIKSLPQEWLWCETWCDDHSKTTAKTIDLCNNPRTKEPKLSAAVRIVSEWTEYDNEIKRFLKEAKKEITQSKASTQHTGN----------------RRDEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q09332-1", "uniprot_id": "UGGG_DROME", "id": "Q09332-1", "name": "UDP-glucose:glycoprotein glucosyltransferase", "aln": "------------------MLRAVALCVSVVLIALYTPTSGESSQSYPITTLINAKWTQTPLYLEIAEYLADEQAGLFWDYVSGVTKLDTVLNEYDTESQQYNAALELVKSHVSSPQLPLLRLVVSMHSLTPRIQTHFQLAEELRSSGSCQSFTFAQVGSELACSFNELQKKLEVPLAKDSLDASVVTYSFDHIFP-GSENNTRTVVLY--GDLGSSQFRTYHKLLEKEAN--AGRIRYILRHQLAKKDKRPVRLSGYGVELHLKSTEYKSQDDAPKPE---AGSTSDEDLANESDVQGFDFKVLKQKHPTLKRALDQLRQRLLQGNDEIAQLKAWEFQDLGLQAAAAIAEIQGDETLQILQYTAHNFPMLARTLLAHKVTDGLRAEVKHNTEAFGRSLNVAPPDGALFINGLFFDADTMDLYSLIETLRSEMRVLESLHSNNVRGSLASSLLALDLTASSKKEFAIDIRD----------------TAVQWVNDIENDVQYRRWPSSVMDLLRPTFPGMLRNIRKNVFNLVLVVDALQPTARSVIKLSESFVIHQAPIRLGLVFDARDANEDN--LADYVAITCAYNYVSQKKDARAALSFLTDIYA-AVGE-TKVVTKKDIVKQLTKEFTSLSFAKAEEFLEEDSTYDYGRELAAEFIQRLGFGDKGQPQALLNGVPMPSNVVTADSDFEEAIFTEIMTHTSNLQKAVYKGELTDNDVAIDYLMNQPHVMPRLNQRILSQEDVKYLDINGV-AYKNLGNVGVLNRLSNRDMTATLMDNLKYFGGKKS--TELIGRASLQFLTIWVFADLETDQGRDLLTHALDYVQSGESV-RVAFIPNTESSSASSRRNLNRLVWAAMQSLPPTQATEQVLKWLKKPKEKIEIP--------------TQLEDILGSTELHLKMLR-VYSQRVLGLNKSQRLVIGNGRLYGPLSSD----ESFDSADFALLARFSSLQYSDKVRQVLKESA-QDVNEEFNSDTLLKLYASLLPRQTKTRFKLPTDLKTDHSVVKLPPKQENLPHFDVAAVLDPASRAAQKLTPILILLRQVLNCQLNLYLIPVPQHSDMPVKNFYRYVVEPEVQFEANGGRSDGPLAKFSGLPANPLLTQQLQVPENWLVEAVRAVYDLDNIKLTDIGGPVHSEFDLEYLLLEGHCFDAASGAPPRGLQLVLGTQSQPTLVDTIVMANLGYFQLKANPGAWSLRLREGKSADIYAISHIEGTNTHHSAGSSEVQVLITSLRSHVVKLRVSKKPGMQQAELLSDDNEQAAQSGMWNSIASSFGGGSANQA------ATDEDTETINIFSVASG--HLYERLLRIMMVSLLKHTKSP-VKFWFLKN-YLSPQFTDFLPHMASEYNFQ--YELVQYKWPRWLHQQTEKQRTIWGYKILFLDVLFPLNVRKIIFVDADAIVRTDIKELYDMDLGGAPYAYTPFCDSRKEMEGFRFWKQGYWRSHLMG---RRYHISALYVVDLKRFRKIAAGDRLRGQYQALSQDPNSLSNLDQDLPNNMIHQVAIKSLPDDWLWCQTWCSDSNFKTAKVIDLCNNPQTKEAKLTAAQRIVPEWKDYDAELKTLMSRIEDHENSHSRDSAVDDSVDDSVEVTTVTPSHEPKHGEL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22023-1", "uniprot_id": "KRE5_YEAST", "id": "P22023-1", "name": "Killer toxin-resistance protein 5", "aln": "----------------------MRLLALVLLLLCAPLRAWTYSLRYGIP-------ESAQVWSILVHLLGDVDNQLLTNLYPLVTGLDDEIDIQENLVALTSNVLRERYDKED--VADLLELYASLYPMG---MIQHDISSNAEQDDANS--SYFVLNGNRYEKPDDVFYLKSKDLTIQQK-VPDVDVIQPYDVVIGTNSEAPILILYGCPTVIDSDFEEFNRNLFMEAMNGEGKFRFIWRSTCSLDGKSVEYPLTHPLEITLQNGSRMSSIPQLKKILYTVPKEILVGADNDDQLHDLEPEELRELDLRVTSLISEFYQYKKDIT----------------------------ATLNFTKSIVNNFPLISKQLIKVSS---VNKDIITSNEELN-SKGFDYNMLGLYINGQNWKITSLTPYNLLTALKTEYQSLLKITNLLQELEPSKCILDSKFLLNKFSQFSLGKLQNLQPIKMDLHTIPGFSESVIYFNDIESDPQYDELVNSVQAFFDKSKFGELPEIKQNWSEIIFVIDFARLEDSEVKEALGGLVRAVNVVSQGYPQRVGLLPFSSDSDKSVVNKIYELKNSTDNLTELKSFLETMLLADG---------------------------------LSANAKHSKHIPVPDVFHLLDELQ-IDETSIIINGEIYPFRKNAWN----YLIAKVIKKDTEFIRKELSNSSPKNKQISVRDLLHYKSANLRHNKYTPNYF-----------------ADSVYSSVNNTALESVCSERIGYYTKNEE---------YNLLHTITLVDDFGSIHALKRLRNLLHTSFVGVRIRIIHVGDISDIWYQLRGSLSQKDPIGSINTFIDALKLKKVKSHTYKKS----------------GLNQLGLHKWLPDIPLFELQKGSFIALNGRFIHLDQNEVPETEHFEAIIKRE----ALRTIDSVFALDLLFPGFSQEIINPDLIEMISSILTRLFYQGTHIYNNGIDYTTESSLPRMDLSEFFRPNNLTMFEDG--KSASIDLLLILDPLEERTQMILSLVEQFRPLKFVNIQVILMPTLELNIVPIRRIYVDDADIVKSITSEDSRS------------DPEVDIEMDVPNSFIVDNN---YRIKKLLIELHS------FSSKTVLSTGNIDGMG------GVCLALVDSAGNIIDKTTTMKTFGYGQFHTDKFLKGCYIKSCDSRYTVQSFSTDGHPDFIPSD----SLDILSYNPQKIAVKISEEP--THEEEYEEG---------------------------------RNNDTIINIFTILESGPDEEERYMQMILSILSKCPETQKVNFFILDQPFISDTLRKSCEYINSSDEMRGNVIFLNYEWPQWLRPQRFSSRRRDVSRFLFLDVLLPQNISKVLYMSPTEVPLDPFDIFQFQGLKRAPLG-------LFRMSGDGYWKEGYWEKMLRENNLEFYSTEPAFLVNLERFRELDAGDKYRIHYQRISTDAMSLVNIGQDLVNNLQLEVPIRFLKGSYKKKLVINDECVSEWKKKINKFASSPGDEDVPGESVSSKYQDSDNAAPLHDEL----------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . : : : : . . *. *:.: *: . ::: : . :: : : . : : : ::* : * :: : .: : :: * . : :*: ::. . : .:::.: *: : : : : : . :: . : :*** :: : :. :: . : : . *:*** . :.:: *: * : : : .* : :. :: :.*::* * * .. :: * : .:::* ::::.:* : .. : : * . * : :. :: : * .: :. : . . : ** . . : ::: : . : ::. . * * . :. .. . : * . *: :. *: . . * . : . : . . : .:: : . : :.. : . :. .: : . :: . :. .. * : : : : . . .. : . . . :: ::** . :* : :: : : :.: : . . *: :* : :. : . . :: .*:.::*: :.:: : :. : :* *: . *: :.* .* .* ** *:::: ::. * :* : : . ..: : :::.:.. : : : .. :***:: .. . ** ::::: : : . : *:*::*.: ::* : . :: . :: :::*.**:**: * .* ::******:* : *.:::.. : :. : .* ** . .*.* :** *** . * . * .. ::*:*::**.: ***: * :** :* *. ** *:.*** **: :*.*: * .: . .: * *: .. .* : : :: ", "identical_positions": 117, "similar_positions": 369, "identity": "7.16%" }, { "cls_id": "homologset.agr.SGD:S000005866", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D1C1-1", "uniprot_id": "UBE2C_MOUSE", "id": "Q9D1C1-1", "name": "Ubiquitin-conjugating enzyme E2 C", "aln": "MASQNRDP---AAASVAAVRKGAEPCGGAARGPVGKRLQQELMILMTSGDKGISAFPESDN-LFKWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILKDKWSALYDVRTILLSIQSLLGEPNIDSPLNTHAAELWK-NPTAFKKYLQETYSKQVSSQDP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZUW6-1", "uniprot_id": "D3ZUW6_RAT", "id": "D3ZUW6-1", "name": "Ubiquitin-conjugating enzyme E2 C", "aln": "MASQNRDP---AAASVAAVRKGAEPCGGAARGPVGKRLQQELMTLMMSGDKGISAFPESDN-LFKWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILKDKWSALYDVRTILLSIQSLLGEPNIESPLNTHAAELWK-NPTAFKKYLQETYSKQVSNQEP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00762-1", "uniprot_id": "UBE2C_HUMAN", "id": "O00762-1", "name": "Ubiquitin-conjugating enzyme E2 C", "aln": "MASQNRDP---AATSVAAARKGAEPSGGAARGPVGKRLQQELMTLMMSGDKGISAFPESDN-LFKWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILKEKWSALYDVRTILLSIQSLLGEPNIDSPLNTHAAELWK-NPTAFKKYLQETYSKQVTSQEP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VTY6-1", "uniprot_id": "UBE2C_DROME", "id": "Q9VTY6-1", "name": "Ubiquitin-conjugating enzyme E2 C", "aln": "-MAQNISPEQSGGAGGGGSKHSDDSMPVKDNHAVSKRLHKELMNLMMANERGISAFPDGEN-IFKWVGTIAGPRNTVYSGQTYRLSLDFPNSYPYAAPVVKFLTSCFHPNVDLQGAICLDILKDKWSALYDVRTILLSIQSLLGEPNNESPLNAQAAMMWN-DQKEYKKYLDAFYEKHKDT---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52492-1", "uniprot_id": "UBC11_YEAST", "id": "P52492-1", "name": "Ubiquitin-conjugating enzyme E2-18 kDa", "aln": "-------------------------MAVEEGGCVTKRLQNELLQLLSSTTESISAFPVDDNDLTYWVGYITGPKDTPYSGLKFKVSLKFPQNYPFHPPMIKFLSPMWHPNVDKSGNICLDILKEKWSAVYNVETILLSLQSLLGEPNNRSPLNAVAAELWDADMEEYRKKVLACYEEIDDY---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ***::**: *: : ..***** .:* : *** * *. .* *.. :::**.**..**: .* :***:. :***** .* *******:****:*:*.*****:******** ****: ** :*. : ::* : *.: ", "identical_positions": 71, "similar_positions": 41, "identity": "38.59%" }, { "cls_id": "homologset.agr.SGD:S000005867", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADH7-1", "uniprot_id": "D4ADH7_RAT", "id": "D4ADH7-1", "name": "DNA-directed RNA polymerase subunit", "aln": "MAAGSVESQRPK---------AASERPVAGQAGILPCLELPSYAAACALVSSRYSCLVAAPHRRHIALSPRYLSRKRTGIREQLDAELLRYSES-LLGVPIAYDNIRVVGELGDIYDDQGHIHLNIEAD-----------FVIFCPKPGQKLMGTVNKVSSSHIGCLVHGCFNASIPKPEQMSYEEWQTLEINVGDELEFDVFRLDSDSAGVFCIRGKLN-------TTSLQHKGSVVSEDVEETVIEEVVEKIPKKKKKK-DKDR-------EVCATVESVTEVADVTDAAAED----------------------EAGLPCSDDVNDFFE-------------EEPKKKKKKKKRHQE-DQDPIFQASDSSGYQSDHKKKKKKRKHSEEAN------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q78WZ7-1", "uniprot_id": "RPA43_MOUSE", "id": "Q78WZ7-1", "name": "DNA-directed RNA polymerase I subunit RPA43", "aln": "MAAGSVESQRSQ---------AASERPVAGQAGVLPCLELPSYAAACALVGSRYSCLVAAPHRRHIALSPRYLSRKRTGIREQLDAELLRYSES-LLGVPIAYDNIRVVGELGDIYDDQGHIHLNIEAD-----------FVIFCPEPGQTLMGTVNKVSSSHIGCLVHGCFNASIPKPEQMSYEEWQTLEIHVGDELEFDVFRLDSDSAGVFCIRGKLS-------TTSLQLKHSAVSEDVAETVVEEVVEKTPKKKKKKKDKDT-------DTCGTVDSVTEVADVTDVTPQE----------------------ETDIPCSDNVNDFFE-------------EEPKKKKKKKKRHQE-DQDPIFQASDSSGYQSDHNKKKKKRKHSEEANFESPKKRQ----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3B726-1", "uniprot_id": "RPA43_HUMAN", "id": "Q3B726-1", "name": "DNA-directed RNA polymerase I subunit RPA43", "aln": "MAAGCSEAPRPA---------AASDGSLVGQAGVLPCLELPTYAAACALVNSRYSCLVAGPHQRHIALSPRYLNRKRTGIREQLDAELLRYSES-LLGVPIAYDNIKVVGELGDIYDDQGHIHLNIEAD-----------FVIFCPEPGQKLMGIVNKVSSSHIGCLVHGCFNASIPKPEQLSAEQWQTMEINMGDELEFEVFRLDSDAAGVFCIRGKLN-------ITSLQFKRSEVSEEVTENGTEEAAKK-PKKKKKK--KDP-------ETYEVDSGTTKLADDADDTPME----------------------ESALQNTNNANGIWE-------------EEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAEFTPPLKCSPKRKGKSNFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PHG8-1", "uniprot_id": "RPA43_DANRE", "id": "Q6PHG8-1", "name": "DNA-directed RNA polymerase I subunit RPA43", "aln": "MANWTQEDGAPTPVTNPSEVSQVSGGSVTGGPAVTSCL-IPSFAEAVKLLKARYSCLVLDTHRRHISLPPVHLKKKKTGIQEQLNAELLKYSNS-LDGVPVAYDNIKVVGQHGNIYDDQGFIHFNIEAS-----------FVIFRPKNGSRLMGVINKMGASHVGCLVHGCFNASVMKPNALTSDQWRDSGLCVGQSLEFEVFQLDADAAGVLLIRGRLDRSRVQELVAQFEQKQVTAESSTEADATEDTTDSPKPKKKKKRKKDKNDTESSMEECVNNSSLQETSEHHQTTTEEDCSANGRHKEKKKKKKRDKNDTESSMDECMNNNSLQETALDTTEEDCNANERHKEKKKKKKRDKQQDSAEIVPTSDSSGYISDKTSRKRALEAGDDTETPAAKKKKKSK-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VM72-1", "uniprot_id": "Q9VM72_DROME", "id": "Q9VM72-1", "name": "", "aln": "------------------------------MAKILQKYIKFSVKELENYASSPESCVRCITTDMHLAMGPYGMANFKHALHELLIRTKVGFYDSGLDGIVLGIKNIKVLGQTAGLRADDPTMHLVINAD-----------FYVFRPKAGAILSGVVRHISRHHVSAVIYRVFNTSIR----FTNQSASREDIAMDQEIKIRIKNFDISNLMPYIEG------------------ELLLENGEAPKNKSIKFGSPPPEEKEVKKEDP--------DEMLDALITEIKKEPEFTPRK-----------------------------------------------------KTSTKRK-----------------NGENGDTTKTKKVKKEIKSEPI-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46669-1", "uniprot_id": "RPA43_YEAST", "id": "P46669-1", "name": "DNA-directed RNA polymerase I subunit RPA43", "aln": "-------------------MSQVKRANENRETARFIKKHKKQVTNPIDEKNGTSNCIVRVPIALYVSLAPMYLENPLQGVMKQHLNPLVMKYNNKVGGVVLGYEGLKILDADPLSKEDTSEKLIKITPDTPFGFTWCHVNLYVWQPQVGDVLEGYIFIQSASHIGLLIHDAFNASIKKNNIPVDWTFVHNDVEEDADVINTDENNGNNNNEDNKDSNGGSNSLGKFSFGNRSLGHWVDSNGEPIDGKLRFTVRNVHTTGRVVSVDG----------TLISDADEEGNGYNSSRSQ----------------------AESLPIVSNKKIVFD---------------DEVSIENKESHKELDLPEVKEDNGSEIVYEENTSESNDGESSDSD-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .*: . :::: * : . .: : : :. : *: :. ..::::. * : * .. : :: *: * * * : . *:. ::: **:*: : . .: . . . .. . * : . : : . : . :.* . : .. .. : .. ", "identical_positions": 15, "similar_positions": 72, "identity": "3.65%" }, { "cls_id": "homologset.agr.SGD:S000005868", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54889-1", "uniprot_id": "RPA1_RAT", "id": "O54889-1", "name": "DNA-directed RNA polymerase I subunit RPA1", "aln": "MLASKHTPWRRLQG-ISFGMYSAEELKKLSVKSITNPRYVDSLGNPSADGLYDLALGPAD-SKEVCSTCVQDFNNCSGHLGHIDLPLTVYNPLLFDKLYLLLRGSCLNCHMLTCPRAAIHLLVCQLKVLDVGALQAVYELERILS-----------RFLEET---------------SDPSAFEIQEELEEYTSKILQNNLLG----SQGAHVKNVCESRSKLVAHFWKTHMA--AKRCPHCKTGRSVVRKEHNSKLTITYP----------------------AMVHKKSGQKDAELPEGAPAAPGIDEAQMGKRG--YLTPSSAQEHLFAIWKNEGFFLNYLFSGL----DDIGPESSFNPSMFFLDFIVVPPSRYRPINRLGDQMFTNGQTVNLQAVMKDAVLIRKLLAVMAQEQKLPCEMTEITIDKENDSSGAIDRSFLSLLPGQSLTDKLYNIWIRLQSHVNIVFDSDMDKLMLEKYP---GIRQILEKKEGLFRKHMMGKRVDYAARSVICPDMYINTNEIGIPMVFATKLTYPQPVTPWNVQELRQAVINGPNVHPGASMVINEDGSRTALSAVDATQREAVAKQLLTPSTGIPKPQGAKVVCRHVKNGDILLLNRQPTLHRPSIQAHRAHILPEEKVLRLHYANCKAYNADFDGDEMNAHFPQSELGRAEAYVLACTDQQYLVPKDGQPLAGLIQDHMVSGANMTIRGCFFTREQYMELVYRGLT-----DKVGRVKLFPPAILKPFPLWTGKQVVSTLLINIIPEDYTPLNLTGKAKIGSKAWVKEKPRP-VPDFDPD--SMCESQVIIREGELLCGVLDKAHYGSSAYGLVHCCYEIYGGETSGRVLTCLARLFTAYLQLYRGFTLGVEDILVKPNADVMRQRIIEESTQCGPRAVRAALNLPEAASCDEIQGKWQDAIWRKDQRDFNMIDMKFKEEVNHYSNEINKACMPFGLHRQFPENNLQMMVQSGAKGSTVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAGGFVTGRFLTGIRPPEFFFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVIQYDLTVRDSDGSVVQFLYGEDGLDIPKTQFLQPKQFP-FLASNYEVIMKSKHLHEVLSRADPQKVLRHFRAIKKWHHRHSSALLRKGAFLSFSQKIQAAVKALN-LEGKTQNGRSPETQQMLQMWHELDEQSRRKYQKRAAPCPDPSLSVWRPDIHFASVSETFEKKIDDYSQEWAAQAEKSHNRSELSLDRLRTLLQLKWQRSLCDPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSVPVFNTKKALRRVKSLKKQLTRVCLGEVLQKVDIQESFCMG--EKQNKFRVYELRFQFLPHAYYQQEKCLRPEDILHFMETRFFKLLMEAIKKKNSKASAFRSVNTRRATQKDLDDTEDSGRNRREEERDEEEEGNIVDAEAEEGDADASDTKRKEKQEEEVDYESEEE----GEEEEEEDVQEEENIKGEGAHQTHEPDEEEGSGLEEE-------SSQNPPCRHSRPQGAEAMERRIQAVRESHS-FIEDYQYDTEESLWCQVTVKLPLMKINFDMSSLVVSLAHNAIVYTTKGITRCLLNETINSKNEKEFVLNTEGINLPELFKYSEVLDLRRLYSNDIHAVANTYGIEAALRVIEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPLNRFGIQSSSSPLQQMTFETSFQFLKQATMMGSHDELKSPSACLVVGKVVKGGTGLFELKQPLR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35134-1", "uniprot_id": "RPA1_MOUSE", "id": "O35134-1", "name": "DNA-directed RNA polymerase I subunit RPA1", "aln": "MLASKHTPWRRLQG-ISFGMYSAEELKKLSVKSITNPRYVDYLGNPSANGLYDLALGPAD-SKEVCATCVQDFNNCSGHLGHIDLPLTVYNPFLFDKLYLLLRGSCLSCHMLTCPRAAIYLLISQLRVLEVGALQAVYELERILS-----------RFLEET---------------GDPSAFEIQEELEEYTSKILQNNLLG----SQGTHVKNVCESRSKLVAQFWKTHMA--AKQCPHCKTGRSVVRKEHNSKLIITYP----------------------ATVHKKSDQEGTELPEGVPEAPGIDKAQMGKRG--YLTPSSAQEHLFAIWKNEGFFLNYLFSGL----DDIGPESSFNPSMFFLDFIVVPPSRYRPVNRLGDQMFTNGQTVNLQAVMKDAVLIRKLLALMAQEQKLPCEMTELTIDKENDSSVAIDRSFLGLLPGPSLTDKLYNIWIRLQSHVNIVFDSEMDKLMLEKYP---GIRQILEKKEGLFRKHMMGKRVDYAARSVICPDMYINTNEIGIPMVFATKLTYPQPVTPWNVQELRQAVINGPNVHPGASMVINEDGSRTALSSVDAAQREAVAKQLLTPATGAPKPQGTKVVCRHVKNGDILLLNRQPTLHRPSIQAHRARILPEEKVLRLHYANCKAYNADFDGDEMNAHFPQSELGRAEAYVLACTDQQYLVPKDGQPLAGLIQDHMVSGANMTIRGCFFTREQYMELVYRGLT-----DKVGRVKLFPPAILKPFPLWTGKQVVSTLLINIIPEDYAPLNLSGKAKIGSKAWVKEKPRP-IPDFDPD--SMCESQVIIREGELLCGVLDKAHYGSSAYGLVHCCYEIYGGETSGRVLTCLARLFTAYLQLYRGFTLGVEDILVKPNADVVRQRIIEESTQCGPQAVKAALSLPETASCDEIQGKWQDAHLSKDQRDFNMIDMKFKEEVNHYSNEINKACMPLGLHRQFPENNLQMMVQSGAKGSTVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAGGFVTGRFLTGIRPPEFFFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVIQYDLTVRDSDGSVVQFLYGEDGLDIPKTQFLQPKQFP-FLAGNYEVIMKSKHLHEVLSRADPQKVLGHIKAIKKWHHKHSGALLRKGAFLSFSQKIQAAVKALN-LKGSIQNGRSPETQQMLQMWYDLDEESRWKYQKRAAPCPDPSLSVWRPDIYFASVSETFEKKIDDFSQEWAAQAERSYKKSELSLDRLRTLLQLKWQRSLCDPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSVPVFDTKKALKKVKSLKKRLTRVCLGEVLQKVDIQESFCMG--EKRNKFQVYELRFQFLPHAYYQQEKCLRPEDILHFMETRFFKLLMEAIKKKKNKASAFRNVNSRRATQKDLNDTEDSGRSQREEERDEEEEGNIVDAEAEEGDADASDTKRKEKQEEEVDYESEEE----GEEEEEEEVQEEGNIKGDGVHQGHEPDEEEHLGLEEEE------SSQKPPRRHSRPQGAEAIKRRIQAVRESYS-FIEDYQYDTEESLWCQVTVKLPLMKINFDMSSLVVSLAHKAIVYTTKGITRCLLNETTNSKNEKELVLNTEGINLPELFKYSEILDLRRLYSNDIHAMANTYGIEAALRVIEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPLNRFGIQSSSSPLQQMTFETSFQFLKQATMMGSHDELKSPSACLVVGKVVKGGTGLFELKQPLR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95602-1", "uniprot_id": "RPA1_HUMAN", "id": "O95602-1", "name": "DNA-directed RNA polymerase I subunit RPA1", "aln": "MLISKNMPWRRLQG-ISFGMYSAEELKKLSVKSITNPRYLDSLGNPSANGLYDLALGPAD-SKEVCSTCVQDFSNCSGHLGHIELPLTVYNPLLFDKLYLLLRGSCLNCHMLTCPRAVIHLLLCQLRVLEVGALQAVYELERILN-----------RFLEEN---------------PDPSASEIREELEQYTTEIVQNNLLG----SQGAHVKNVCESKSKLIALFWKAHMN--AKRCPHCKTGRSVVRKEHNSKLTITFP----------------------AMVHRTAGQKDSEP-------LGIEEAQIGKRG--YLTPTSAREHLSALWKNEGFFLNYLFSGM----DDDGMESRFNPSVFFLDFLVVPPSRYRPVSRLGDQMFTNGQTVNLQAVMKDVVLIRKLLALMAQEQKLPEEVATPTTDEEKDSLIAIDRSFLSTLPGQSLIDKLYNIWIRLQSHVNIVFDSEMDKLMMDKYP---GIRQILEKKEGLFRKHMMGKRVDYAARSVICPDMYINTNEIGIPMVFATKLTYPQPVTPWNVQELRQAVINGPNVHPGASMVINEDGSRTALSAVDMTQREAVAKQLLTPATGAPKPQGTKIVCRHVKNGDILLLNRQPTLHRPSIQAHRARILPEEKVLRLHYANCKAYNADFDGDEMNAHFPQSELGRAEAYVLACTDQQYLVPKDGQPLAGLIQDHMVSGASMTTRGCFFTREHYMELVYRGLT-----DKVGRVKLLSPSILKPFPLWTGKQVVSTLLINIIPEDHIPLNLSGKAKITGKAWVKETPRS-VPGFNPD--SMCESQVIIREGELLCGVLDKAHYGSSAYGLVHCCYEIYGGETSGKVLTCLARLFTAYLQLYRGFTLGVEDILVKPKADVKRQRIIEESTHCGPQAVRAALNLPEAASYDEVRGKWQDAHLGKDQRDFNMIDLKFKEEVNHYSNEINKACMPFGLHRQFPENSLQMMVQSGAKGSTVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAGGFVTGRFLTGIKPPEFFFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVVQYDLTVRDSDGSVVQFLYGEDGLDIPKTQFLQPKQFP-FLASNYEVIMKSQHLHEVLSRADPKKALHHFRAIKKWQSKHPNTLLRRGAFLSYSQKIQEAVKALK-LESENRNGRSPGTQEMLRMWYELDEESRRKYQKKAAACPDPSLSVWRPDIYFASVSETFETKVDDYSQEWAAQTEKSYEKSELSLDRLRTLLQLKWQRSLCEPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSVPVLNTKKALKRVKSLKKQLTRVCLGEVLQKIDVQESFCME--EKQNKFQVYQLRFQFLPHAYYQQEKCLRPEDILRFMETRFFKLLMESIKKKNNKASAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMERRVQAVREIHP-FIDDYQYDTEESLWCQVTVKLPLMKINFDMSSLVVSLAHGAVIYATKGITRCLLNETTNNKNEKELVLNTEGINLPELFKYAEVLDLRRLYSNDIHAIANTYGIEAALRVIEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPLNRFGIRSNSSPLQQMTFETSFQFLKQATMLGSHDELRSPSACLVVGKVVRGGTGLFELKQPLR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P91875-1", "uniprot_id": "RPA1_DROME", "id": "P91875-1", "name": "DNA-directed RNA polymerase I subunit A", "aln": "MGSKRAMDVHMFPSDLEFAVFTDQEIRKLSVVKVITGITFDALGHAIPGGLYDIRMGSYGRCMDPCGTCLK-LQDCPGHMGHIELGTPVYNPFFIKFVQRLLCIFCLHCYKLQMKDHECEIIMLQLRLIDAGYIIEAQELELFKS-----------EIVCQN---------------TEN-LVAIKNGDMVHPHIAAMYKLLE----KNEKNSSNSTKTSCSLRTAITHSALQRLGKKCRHCNKSMRFVRYMHRRLVFYVTL----------------------ADIKER---------------VGTGAETGGQNK--VIFADECRRYLRQIYANYPELLKLLVPVLGLSNTDLTQGDRSPVDLFFMDTLPVTPPRARPLNMVGDMLKGNPQTDIYINIIENNHVLNVVLKYMKGGQ---------------EKLTEEAKAAYQTLKGETAHEKLYTAWLALQMSVDVLLDVNMSREMKSGE----GLKQIIEKKSGLIRSHMMGKRVNYAARTVITPDPNINVDEIGIPDIFAKKLSYPVPVTEWNVTELRKMVMNGPDVHPGANYIQDKNGFTTYIPADNASKRESLAKLLLSNPK-----DGIKIVHRHVLNGDVLLLNRQPSLHKPSIMGHKARILHGEKTFRLHYSNCKAYNADFDGDEMNAHYPQSEVARAEAYNLVNVASNYLVPKDGTPLGGLIQDHVISGVKLSIRGRFFNREDYQQLVFQGLS-----QLKKDIKLLPPTILKPAVLWSGKQILSTIIINIIPEGYERINLDSFAKIAGKNWNVSRPRPPICGTNPEGNDLSESQVQIRNGELLVGVLDKQQYGATTYGLIHCMYELYGGDVSTLLLTAFTKVFTFFLQLEG-FTLGVKDILVTDVADRKRRKIIRECRNVGNSAVAAALELEDEPPHDELVEKMEAAYVK-DSKFRVLLDRKYKSLLDGYTNDINSTCLPRGLITKFPSNNLQLMVLSGAKGSMVNTMQISCLLGQIELEGKRPPLMISGKSLPSFTSFETSPKSGGFIDGRFMTGIQPQDFFFHCMAGREGLIDTAVKTSRSGYLQRCLIKHLEGLSVHYDLTVRDSDNSVVQFLYGEDGLDILKSKFFNDKFCADFLTQNATAILRPAQLQLMKDEEQLAKVQRHEKHIRSWEKKKPAKLR--AAFTHFSEELREEVEVKRPNEINSKTGRRRFDEGLLKLWKKADAEDKALYRKKYARCPDPTVAVYKQDLYYGSVSERTRKLITDYAKRKPALKET-----------IADIMRVKTIKSLAAPGEPVGLIAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMLASSNIKTPSMDIPIKPGQQ--HQAEKLRINLNSVTLANLLEYVHVSTGLTLD--PERS--YEYDMRFQFLPREVYKEDYGVRPKHIIKYMHQTFFKQLIRAILKVSNASRTTKIVVID--DKKDADKDDDNDLDNGDEVGRSKAKANDDDSSDDNDDDDATGVKLKQRKTDEKDYD------------DPDDVEELHDANDDDDEAEDEDDEEKGQDGNDND------------------GDDKAVER-----LLSND-MVKAYTYDKENHLWCQVKLNLSVRYQKPDLTSIIRELAGKSVVHQVQHIKRAIIYK----GNDDDQLLKTDGINIGEMFQHNKILDLNRLYSNDIHAIARTYGIEAASQVIVKEVSNVFKVYGITVDRRHLSLIADYMTFDGTFQPLSRKGMEHSSSPLQQMSFESSLQFLKSAAGFGRADELSSPSSRLMVGLPVRNGTGAFELLTKIC---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10964-1", "uniprot_id": "RPA1_YEAST", "id": "P10964-1", "name": "DNA-directed RNA polymerase I subunit RPA190", "aln": "MDISKPVGS-EITS-VDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFL--RNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITLGSLNSSMYTDDEAIEDNEDEMDGEGSKQSKDISSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLS--RGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGFIRQDMIKKQKQAKKLDGSNEASANDEESFDVGRNPTTRPKTGSTYILSTEVKNILDTVFRKEQCVLQYVFHSR----PNLSR-KLVKADSFFMDVLVVPPTRFRLPSKLGEEVHENSQNQLLSKVLTTSLLIRDLN----------------------DDLSKLQKDKVSLEDRRVIFSRLMNAFVTIQNDVNAFIDSTKAQGRTSGKVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGK---------------GSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATA-FTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFC---LDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHS----------------------------------------------------KEPHYKQSVKY-DPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKLFKSSDGVNE---KKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMTLNTFHFAGHGAANVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSD-EQADTFCKSISKVLLSEVIDKVIVTETTGTSNTAGGNAARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRTTGPDIGVAVPRLQTDVANSSSNSKRLEEDNDEEQSHKKTKQAVSYDEPDEDEIETMREAEKSSD-------------EEGIDSDKESDSDSEDEDVDMNEQINKSIVEAN------------------NNMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPE----PENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNAA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .: : . :.*.: : :*:::**. .: . .* **:. ..****: :*. : *.** . *.** ***:* . ***:::. : * ** *: : :*:::: * : :*: : . : :. . ::. : * .. . . .* : : : :* :* .* : . :. * : : . . :. * :: : .*: :. : . . **:* : *.*.* * . :*: : * *. :: ::. : :. : .:* . :: :* *: .:* : . *::* :***.**:*.*******:****:** ** *:.:***:* :** **:** *** :*: ***: *:***: ***. : :::* . : . . :*:::*: **: .. * * **: * *::*:****:**:.*: .*:.::* **.:****:* ************ *:**.* .**** *. . .:**.*..* *: ******: :*. :: :. **.**.* : :: : : :.*:*:** **:***:::*:::*: * . :** . ** .: * . *.:* :::* ** *:*** :**:: **::*. :*:** :.: :*: : ::** :: ** *:.*: :. .: * *:. . . * *. . .* . .. *: . *.. ::* .. :: :.:: . *:* * :** *.:* *. ****** **. ** ***** ***:* *:* ***:**.* .:* . :**:: *** :**:* :::**********:***************: *:***: : ** ::**:*.::***:** *.:** * ..: * .::: : : .. : .. : : .:. ::. : : *: . ** :: :. : .**** . : .: .. . : : ::::* :** ***.**::*:**:****************:* ************:* **: **** * :*: . .:...: :. * *.:::: : : . * ::::*: . *.:: : :.: . : *:: * :* * . : . : . . .. : .:. . :. : : : * . : : ::. : . :. : :*: . : . : ::* :: * :* *. **:..::*. : : .:: .:. ::: * *.: : :: . :* *:*:*: ::. .:*: : ***: *: .***:*** ..* :*:.:** *.*:*. ***.*:** * :*.: .:.* *:. .:*.: :*::*:: ***..*. . ::* ***: ::** . *** *:: : ", "identical_positions": 431, "similar_positions": 513, "identity": "23.84%" }, { "cls_id": "homologset.agr.SGD:S000005871", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3U1N2-1", "uniprot_id": "SRBP2_MOUSE", "id": "Q3U1N2-1", "name": "Sterol regulatory element-binding protein 2", "aln": "MDESSELGVLETMETLTELG--DELTLGDIDEMLQFVSNQVGEFPDLFSEQLCSSFPGGGSNG----GSG---NNSSGRGNNGGATDPAVQRSFSQVPLSTFSPSAASPQAPALQVKVS----PTPPRATPVLQPRPQPQPQPP------------AQLQQQTVMITPTFSTAPQTRIIQQPLIY-QNAATSFQ--------VLQPQVQSLVTSPQVQPVT-IQQQVQTVQAQRVLTQTANGTLQTLAPATVQTVAAPQVQQVPVLV-QPQIIKTDSLVLTTLKTDGSPVMAAVQNP-ALTALTAPIQTAALQVPTLVGSNGTILTTMPVMMGQ-EKVPIKQVPGG-----------VKQLDPP------KEGERRTTHNIIEKRYRSSINDKIIELKDLVMGTDAKMHKS-----GVLRKAIDYIKYLQQVNHKLRQENMVLKLANQKNKLLKGIDLGSLVDSDVDLKIDDFNQNVLL-MSPPASDSGSQ--AGFSPYSI------------DSEPGSPLLDDAKVKDEPDSPPVALGMVDRSRILLCVLTFLGLSFNPLTSLLQWGGAHNTDQHP--YSGSGRSVLSLESGA---GGWFDWMVPTLLLWLVNGVIVLSVFVKLLVHGEPVIRPHSRPSVTFWRHRKQADLDLAKGDFAAAAANLQTCLSVLGRALPTSRLDLACSLSWNVIRYSLQKLRLVRWLLKKVFQRWRATPATAAGFEDEAKSSARDAALAYHRLHQLHITGKLPAGSACSDVHMALCAVNLAECAEEKILPSTLIEIHLTAAMGLKTRCGGKLGFLASYFLNRAQSL-CGPEHSTVPDSLRWLCHPLGQKFFMERSWSIKSAAKESLYCAQRSPADPIAQVHQAFCKNLLERAVESLVKPQAKKKAGDQEEESCEFSSALEYLKLLHSFVDSVGFVTSPFSSSSVLRSALGPDVICRWWTSAVTMAISWLQGDDAAVRSRFTEVERVPKALEVTESPLVKAVFYTCRAMHASLSG-KADGQQNSFCHCERASGHLWSSLNVSGTTSDPSLNHVIQLFTCDLLLSLRTALWQKQASASQLLGETYH-----ASGTELAGFQRDLGSLRRLAHSFRPAYRKVFLHEATVRLMAGASPTRTHQLLEHSLRRRP---TQNTKHGEVDTWPGQRERATAILLACRHLPLSFLSSPGQRAVLLAEAARTLEKVGDRRSCSDCQQMIVKLGGGTAIAAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3T1I5-1", "uniprot_id": "SRBP2_RAT", "id": "Q3T1I5-1", "name": "Sterol regulatory element-binding protein 2", "aln": "MDENSELGGLETMETLTELG--DELTLGDIDEMLQFVSNQVGEFSDLFSEQLCSSFPGGGGGS----GSGGTSNNSSGRGTSGGAADPAVQRSFSQVPLSTFSPSSTSPQAPALQVKVS----PTPPRATPVLQPRPQPQPQPP------------AQLQQQTVMITPTFSTAPQTRIIQQPLIY-QNAATSFQ--------VLQPQVQSLVTSSQVQPVT-IQQQVQTVQAQRVLTQTANGTLQTLAPATVQTVATPQVQQVPVLV-QPQIIKTDSLVLTTLKTDGSPVMAAVQNP-ALTALTAPIQTAALQVPTLVGSNGAILTTMPVMMGQ-EKVPIKQVPGG-----------VKQLEPP------KEGERRTTHNIIEKRYRSSINDKIIELKDLVMGTDAKMHKS-----GVLRKAIDYIKYLQQVNHKLRQENMVLKLANQKNKLLKGIDLGSLVDSDVDLKIDDFNQNVLL-MSPPASDSGSQ--AGFSPYSI------------DSEPGSPLLDDAKVKDEPDSPPVALGMVDRSRILLCVLTFLGLSFNPLTSLLQWGGAHNPDQHP--YSGSGRNVLSLESGS---GGWFDWMMPTLLLWLLNGVIVLSVFVKLLVHGEPVIRPHSRSSVTFWRHRKQADLDLAKGDFAAAAANLQTCLSVLGRALPTSRLDLACSLSWNVIRYSLQKLRLVRWLLKKVFQRWRATPATAAGFEDEAKSSARDAALAYHRLHQLHITGKLPAGSACSDVHMALCAVNLAECAEEKIPPSTLVEIHLTAAMGLKTRCGGKLGFLASYFLNRAQSL-CGPEHSAVPDSLRWLCHPLGQKFFMERSWSIKSAAKDSLYCAQRNPADPIAQVHQAFCKHLLERAVEALVKPQAKKKAGDREEESCEFSSALEFLKLLHSFVDSVGFVASPFSSSSVLRSALGPDVVCRWWTSAITVAISWLQGDDAAVRSHFTEVERVPKALEVTESPLVKAVFYACRAMHASLSG-KADGQQNSFCHCERASGHLWSSLNVSGTTSDPSLNHVVQLLTCDLLLSLRTTLWQKQASASQLLGETYH-----ASGTELAGFQRDLGSLRRLAHSFRPAYRKVFLHEATVRLMAGASPTRTHQLLEHSLRRRT---TQNTKHGEVDTWPGQRERATAILLACRHLPLSFLSSPGQRAVLLAEAARTLEKVGDRRSCSDCQQMIVKLGGGTAIAAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12772-1", "uniprot_id": "SRBP2_HUMAN", "id": "Q12772-1", "name": "Sterol regulatory element-binding protein 2", "aln": "MDDSGELGGLETMETLTELG--DELTLGDIDEMLQFVSNQVGEFPDLFSEQLCSSFPGSGGSGSSSGSSGSSSSSSNGRGSSSGAVDPSVQRSFTQVTLPSFSPSAASPQAPTLQVKVSPTSVPTTPRATPILQPRPQPQPQPQ------------TQLQQQTVMITPTFSTTPQTRIIQQPLIY-QNAATSFQ--------VLQPQVQSLVTSSQVQPVT-IQQQVQTVQAQRVLTQTANGTLQTLAPATVQTVAAPQVQQVPVLV-QPQIIKTDSLVLTTLKTDGSPVMAAVQNP-ALTALTTPIQTAALQVPTLVGSSGTILTTMPVMMGQ-EKVPIKQVPGG-----------VKQLEPP------KEGERRTTHNIIEKRYRSSINDKIIELKDLVMGTDAKMHKS-----GVLRKAIDYIKYLQQVNHKLRQENMVLKLANQKNKLLKGIDLGSLVDNEVDLKIEDFNQNVLL-MSPPASDSGSQ--AGFSPYSI------------DSEPGSPLLDDAKVKDEPDSPPVALGMVDRSRILLCVLTFLCLSFNPLTSLLQWGGAHDSDQHP--HSGSGRSVLSFESGS---GGWFDWMMPTLLLWLVNGVIVLSVFVKLLVHGEPVIRPHSRSSVTFWRHRKQADLDLARGDFAAAAGNLQTCLAVLGRALPTSRLDLACSLSWNVIRYSLQKLRLVRWLLKKVFQCRRATPATEAGFEDEAKTSARDAALAYHRLHQLHITGKLPAGSACSDVHMALCAVNLAECAEEKIPPSTLVEIHLTAAMGLKTRCGGKLGFLASYFLSRAQSL-CGPEHSAVPDSLRWLCHPLGQKFFMERSWSVKSAAKESLYCAQRNPADPIAQVHQAFCKNLLERAIESLVKPQAKKKAGDQEEESCEFSSALEYLKLLHSFVDSVGVMSPPLSRSSVLKSALGPDIICRWWTSAITVAISWLQGDDAAVRSHFTKVERIPKALEVTESPLVKAIFHACRAMHASLPG-KADGQQSSFCHCERASGHLWSSLNVSGATSDPALNHVVQLLTCDLLLSLRTALWQKQASASQAVGETYH-----ASGAELAGFQRDLGSLRRLAHSFRPAYRKVFLHEATVRLMAGASPTRTHQLLEHSLRRRT---TQSTKHGEVDAWPGQRERATAILLACRHLPLSFLSSPGQRAVLLAEAARTLEKVGDRRSCNDCQQMIVKLGGGTAIAAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KNA7-1", "uniprot_id": "SRBP2_DANRE", "id": "A3KNA7-1", "name": "Sterol regulatory element-binding protein 2", "aln": "MDASEFMDTMD--PSLSELG--DEFTLGDIDEMLQFVSNQV-DFPDIFEDQMGG------------G--------ATARTLPQAVPSAILTPPHTPVQTSSQTHTQTLTQAHTQTHTQT----HTQTRTPPVLQPRPQPITQVQTQTFPMQTLAVQTQAQPQTVMITP---TATPSRFIQNQVICQQNNATSFQ--------VLQPQMQSIMTSPQVQPMT-IQH-------QRVLTPAG-QTIQTLS--TAPTTVHTMSQQVPVLVHQPQILKTDSLLLTT-KPDGTQVLSTVQSPTGITTLTTPIQTTALQMPTLMSSN--ILTTVPVVMGGGDKLPIKQLSSGPAHNIGGARVGVEQSPVVGPGGVVKEGERRTTHNIIEKRYRSSINDKILELRDLVLGNDAKMHKS-----GVLRKAIDYIKYLQQVNHKLRQENLTLKMANQKNK--------SACVSDVDLELK---AEVSL-ISPPPSDSGSSSPAQLSPYCI------------DSEPGSPLLEHEQLKSEPDSP-SCVGVMDRSRLLLCALSFLCLSLNPLPSLLGAEAPAGSPEVA--GHGPTRTLFSLPAQTQSFGAWLWCVLPFLLVWVVSGVGVVWGCVRVLYLWEPVTPLHSPTSVRFWRHRKQADLQLYRGDYAGAVLSLQTCLSVLSRVLPVTTLDIMCSLSWNLIRYCLRRPAPLGWLVRLVGGRHEG---------EESQTSSRDAALVYHKLSQLQLTGQMER-RPLWGVCVSLSAVNLCESAEGKLTATQQVQVYVTAAISVRAALGKHLTCLPAYLLSCAEALTCQSDSKPLPDCLRWIFTPLGRQFFLSCDWSVRSESDGQIFTSARDKADPIAQLHRCFCQKLLERATHTLIEPQSREDAG-------EFTGVLEFLQLLNSCTEDSAPSTAPFPALANQSSTSVRDPVCRWWASVLTAAVHWLQGDDASVRSLLAEAERMPRALHTLDHPLPKAVLALCKAVQMSVCPQKGEGVVSCLSHCQRASAQLH--ISVCQSHNNTWLHKGVELLVCDLLLTLRTSLWQRGGGSN---GEPGP-----APGSQLSGFQRDLSSLRRLGQAHRQAQHKLFLHETTVRLMAGASPTRTHQLLRHRTHNYT---TTDG-----ECVLGERERAHAILLACRHLPLPLLTPPGHRARLLAEAKRTLERVGDRRSLQDCQHILLRLSGGTTIAAS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P56720-2", "uniprot_id": "SRBP1_RAT", "id": "P56720-2", "name": "Sterol regulatory element-binding protein 1", "aln": "MDELP-FGEAALEQALAEVCEMDAALLTDIEDMLQLINNQDSDFPGLFDAPYAGGETGDTGPS----SPGASSPESFSSP-ASLGSSLEAFLGGPKVTPAPLSPPPSAPTAVKMYPSVP----PFSPGPGIKEEPVPLTILQPP------------APQPSPGTLLPPSFPPP-PVQLSPAPVLGYSSLPSGFS-GTLPGNTQQTPSSLPLGSTPGISPTP-LHTQVQSSAAQQPPPASAAPRMS---------TVASQIQQVPVVL-QPHFIKADSLLLTAVKTDTG---ATMKTA-GINTLAPGTAVQAGPLQTLVSGG-TILATVPLVVDT-DKLPIHRLAAG-----------GKALGSAQ-----SRGEKRTAHNAIEKRYRSSINDKIVELKDLVVGTEAKLNKS-----AVLRKAIDYIRFLQHSNQKLKQENLTLR-SAHKSKSLKDLVSACGSGGGTDVSMEGMKPEVVETLTPPPSDAGSP--SQSSPLSLGSRGSSSGGS--DSEPDSPAFEDNQVKAQRLPS-HSRGMLDRSRLALCVLVFLCLTCNPLASLFG-WGILTPSDASGVHRSSGRSMLEAESRDG--SNWTQWLLP-PLVWLANGLLVLACLALLFVYGEPVTRPHSGPAVHFWRHRKQADLDLARGDFAQAAQQLWLALQALGRPLPTSNLDLACSLLWNLVRHLLQRLWVGRWLAGQAGGLQRD-----YRLRKDARASARDAAVVYHKLHQLHAMGKYTG-GHLVASNLALSALNLAECAGDAISMATLAEIYVAAALRVKTSLPRALHFLTRFFLSSARQA-CLAQSGAVPLAMQWLCHPVGHRFFVDGDWAVHGAPQESLYSVAGNPVDPLAQVTRLFCEHLLERALNCIAQP--SPGAADGDR---EFSDALGYLQLLNSCSDAVGAPACSFSVSSSMATTTGTDPVAKWWASLTAVVIHWLRRDEEAAERLYPLVEHIPQVLQETERPLPRAALYSFKAARALLDHRKVESSPASLAICEKASGYLRDSLASTSTAS--SIDKAMQLLLCDLLLVARTSLWRRQQSAASAQGAHGTSNGPQASALELRGFQHDLSSLRRLAQSFRPAMRRVFLHEATARLMAGASPARTHQLLDRSLRRRAGSSGKGGAAAELEPRPTWREHTEALLLASCYLPPAFLSAPGQRVSMLAEAARTVEKLGDHRLLLDCQQMLLRLGGGTTVTSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTN3-1", "uniprot_id": "SRBP1_MOUSE", "id": "Q9WTN3-1", "name": "Sterol regulatory element-binding protein 1", "aln": "MDELA-FGEAALEQTLAEMCELDTAVLNDIEDMLQLINNQDSDFPGLFDAPYAGGETGDTGPS----SPGANSPESFSS--ASLASSLEAFLGGPKVTPAPLSPPPSAPAALKMYPSVS----PFSPGPGIKEEPVPLTILQPA------------APQPSPGTLLPPSFPAP-PVQLSPAPVLGYSSLPSGFS-GTLPGNTQQPPSSLPLAPAPGVLPTPALHTQVQSLASQQPLPASAAPRTN---------TVTSQVQQVPVVL-QPHFIKADSLLLTAVKTDAG---ATVKTA-GISTLAPGTAVQAGPLQTLVSGG-TILATVPLVVDT-DKLPIHRLAAG-----------SKALGSAQ-----SRGEKRTAHNAIEKRYRSSINDKIVELKDLVVGTEAKLNKS-----AVLRKAIDYIRFLQHSNQKLKQENLTLR-SAHKSKSLKDLVSACGSGGGTDVSMEGMKPEVVETLTPPPSDAGSP--SQSSPLSFGSRASSSGGS--DSEPDSPAFEDSQVKAQRLPS-HSRGMLDRSRLALCVLAFLCLTCNPLASLFG-WGILTPSDATGTHRSSGRSMLEAESRDG--SNWTQWLLP-PLVWLANGLLVLACLALLFVYGEPVTRPHSGPAVHFWRHRKQADLDLARGDFPQAAQQLWLALQALGRPLPTSNLDLACSLLWNLIRHLLQRLWVGRWLAGQAGGLLRD-----RGLRKDARASARDAAVVYHKLHQLHAMGKYTG-GHLAASNLALSALNLAECAGDAISMATLAEIYVAAALRVKTSLPRALHFLTRFFLSSARQA-CLAQSGSVPLAMQWLCHPVGHRFFVDGDWAVHGAPPESLYSVAGNPVDPLAQVTRLFREHLLERALNCIAQP--SPGAADGDR---EFSDALGYLQLLNSCSDAAGAPACSFSVSSSMAATTGPDPVAKWWASLTAVVIHWLRRDEEAAERLYPLVEHIPQVLQDTERPLPRAALYSFKAARALLDHRKVESSPASLAICEKASGYLRDSLASTPTGS--SIDKAMQLLLCDLLLVARTSLWQRQQSPASVQVAHGTSNGPQASALELRGFQHDLSSLRRLAQSFRPAMRRVFLHEATARLMAGASPARTHQLLDRSLRRRAGSSGKGGTTAELEPRPTWREHTEALLLASCYLPPAFLSAPGQRMSMLAEAARTVEKLGDHRLLLDCQQMLLRLGGGTTVTSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36956-1", "uniprot_id": "SRBP1_HUMAN", "id": "P36956-1", "name": "Sterol regulatory element-binding protein 1", "aln": "MDEPP-FSEAALEQALGEPCDLDAALLTDIEDMLQLINNQDSDFPGLFDPPYAGSGAGGTDPA----SPDTSSPGSLSPPPATLSSSLEAFLSGPQAAPSPLSPPQPAPTPLKMYPSMP----AFSPGPGIKEESVPLSILQTP------------TPQPLPGALLPQSFPAPAPPQFSSTPVLGYPSPPGGFSTGSPPGNTQQPLPGLPLASPPGVPPVS-LHTQVQSVVPQQLLTVTAAPTAAPVT-----TTVTSQIQQVPVLL-QPHFIKADSLLLTAMKTDG----ATVKAA-GLSPLVSGTTVQTGPLPTLVSGG-TILATVPLVVDA-EKLPINRLAAG-----------SKAPASAQ-----SRGEKRTAHNAIEKRYRSSINDKIIELKDLVVGTEAKLNKS-----AVLRKAIDYIRFLQHSNQKLKQENLSLRTAVHKSKSLKDLVSACGSGGNTDVLMEGVKTEVEDTLTPPPSDAGSP--FQSSPLSLGSRGSGSGGSGSDSEPDSPVFEDSKAKPEQRPSLHSRGMLDRSRLALCTLVFLCLSCNPLASLLGARGLPSPSDTTSVYHSPGRNVLGTESRDG--PGWAQWLLP-PVVWLLNGLLVLVSLVLLFVYGEPVTRPHSGPAVYFWRHRKQADLDLARGDFAQAAQQLWLALRALGRPLPTSHLDLACSLLWNLIRHLLQRLWVGRWLAGRAGGLQQD-----CALRVDASASARDAALVYHKLHQLHTMGKHTG-GHLTATNLALSALNLAECAGDAVSVATLAEIYVAAALRVKTSLPRALHFLTRFFLSSARQA-CLAQSGSVPPAMQWLCHPVGHRFFVDGDWSVLSTPWESLYSLAGNPVDPLAQVTQLFREHLLERALNCVTQPNPSPGSADGDK---EFSDALGYLQLLNSCSDAAGAPAYSFSISSSMATTTGVDPVAKWWASLTAVVIHWLRRDEEAAERLCPLVEHLPRVLQESERPLPRAALHSFKAARALLGCAKAESGPASLTICEKASGYLQDSLATTPASS--SIDKAVQLFLCDLLLVVRTSLWRQQQPPAPAPAAQGTSSRPQASALELRGFQRDLSSLRRLAQSFRPAMRRVFLHEATARLMAGASPTRTHQLLDRSLRRRAGPGGKGGAVAELEPRPTRREHAEALLLASCYLPPGFLSAPGQRVGMLAEAARTLEKLGDRRLLHDCQQMLMRLGGGTTVTSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22415-1", "uniprot_id": "USF1_HUMAN", "id": "P22415-1", "name": "Upstream stimulatory factor 1", "aln": "----------------------------------------------------------------------------MKGQQKTAETEEGTVQIQEGAVATGEDPTSVAIASIQSAATFP------DPNVKYVFRTENGGQVMYR------------VIQVSEGQLDGQTEGTGAISGYPATQSMTQAVIQGAFT-------------SDDAVDTEGTAAET-----------------------------------------------HYTYFPSTAVGDGAGGTTSGSTAAVVTTQGSEALLGQATPPGTGQFFVMMSPQEVLQGGSQRSIAP----RTHPYSPK-----------SEAPRTTR------DEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKACDYIQELRQSNHRLSEELQGLD---------------------------------------------------------------------------QLQLDNDVLRQQVEDLKNKNLLLRAQLRHHGLEVVIKNDSN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33122-1", "uniprot_id": "TYE7_YEAST", "id": "P33122-1", "name": "Transcription factor TYE7", "aln": "---------------------------------------------------------------------------MNSILDRNVRSSETTLIKPESEFDNWLSDENDGASHINVNKDSSS---VLSASSSTWFEPLENIISSAS--------------SSSIGSPIEDQFISSNNEESALFPTDQFFSNPSSYS--------------HSPEVSSSIKREE----------------------------------------------------DDNALSLADFEPASLQLMPNMINT--------DNNDDSTPLKNEIELNDSFIKTNLDAKETKKRAPRKRLTPF----------------------------QKQAHNKIEKRYRININTKIARLQQIIPWVASEQTAF---------EVGDSVKKQDEDGAETAAT-------------------------------------------------------------------------------TPLPSAAATSTKLNKSMILEKAVDYILYLQNNERLYEMEVQRLKSEIDTLKQDQK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . .. . .: . :: . . : : . : : : . :: ** :*:* * .** * .* .:: : :. * :: . . . : : . . ", "identical_positions": 10, "similar_positions": 41, "identity": "0.82%" }, { "cls_id": "homologset.agr.SGD:S000005873", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRU9-1", "uniprot_id": "D3ZRU9_RAT", "id": "D3ZRU9-1", "name": "Translesion synthesis protein REV1", "aln": "---MVAWGG----AEGPLRSSTMRRGGWRKRA-EEDGWEKWGGYMAAKVQKLEEQFRSDAAKQ--KDGTASAIFSGVAIYVNGYTDPSAEELRNLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKAGRLLSSVPYQLYTKPSTAQKSLNFTPVCKPEEPVPGPSE-----------------IAKQLTNRVNHIIKKIETENEVKANGVSSWNEDSADDGFSSEGLGQTFPGRKQNGVMHPRDT--AVIFNGHAHSSNGALKTQDCLVPVDHSVASRLSLDSTQEEKR--AEKSSTDFRDCSR-QHLQHSTTNADTLCSP---------HRTSSLSPS-LHSNTKINGAHHSTVQGPSSTKSTS-ALTLSKVAPSVPSKPSDCSFISDFYSRSRLHHISTWKCELTEFVSALQ--RQRSG--VFPGREKLKKVKTGRSSLVVTDTGDMSVLSSPRPQSCVMHVDMDCFFVSVGIRNRPDLKGKPVAVTSNRG---TGRAPLRPGANPQLEWQYYQNK---LLKGKAADIPDSSVWENQDSAQTNGIDS---VLSKAEIASCSYEARQVGIKNGMFFGHAKQLCPN---LQAVPYDFHACREVAQALYETLASYTHS--IEAVSCDEALID--VTDILAETKLSPEEFAAALRMEIKNKT-QCAASVGIGSNILLARMATKKAKPDGQYHLQP-DEVDDFIRGQLVTSLPGVGRSMESKLAS--LGIKTCGDLQC-LTMAKLQKEFGPKTGQMLYRFCRGLDDRP-------VRTEKERKSVSAEINYGIRFTQPREAEAFLLSLSGEIQSRLEAAGMKGKRLTLKIMVRKPGAPIETAKFGGHGICDNIARTVTLDQATDSAKIIGKATLNMFHTMKLNISDMRGVGIQVHQLVPANLHPSTCSSRPSAQSSLFSGLPHSVRDLFQLQKAKKPTEEEHNEG-LAAVDLEVSSNSRACGLLSPPSAHLAT-VSPDANRGECSRKWNGLHSPIGGQSRLNLSIEVPSPSQIDQSVLEALPPDIREQVEQAYAAQQGEPRGSKKKEPVNGCSSGVLPHPVGTVLLQIP-EPQEPNNSDTRISVIALPAFSQVDPDVFAALPAELQKELKAAYDQRQRQGEDTTQQQPASTSVPKNPLLQLKPPAMKDKRNKRKNPIGSPRK-------------IQSLPG---TSGSPQKLMDGFLQHE----ERPLEEVSASTPGAQSLSGLQCGSQSSCFRPAAPNLAGAVEFSDVKTLLKEWITTIS---DPMEEDILQVVKYCTDLIEEKDLEKLDLVIKYMKRLMQQ--SVESVWN--MAFDFILDNVQVVLQQTYGSTLKVT---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q920Q2-1", "uniprot_id": "REV1_MOUSE", "id": "Q920Q2-1", "name": "Translesion synthesis protein REV1", "aln": "----------------------MRRGGWRKRT-ENDGWEKWGGYMAAKVQKLEEQFRTDAANQ--KDGTASAIFSGVAIYVNGYTDPSAEELRNLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKAGRLLSSAPYQLYTKPSAAQKSLNFNPVCKPEDPGPGPSN-----------------RAKQLNNRVNHIIKKIETESEVKANGLSSWNEDGVNDDFSFEDLEHTFPGRKQNGVMHPRDT--AVIFNGHTHSSNGALKTQDCLVPVGNSVASRLSLDSTQEEKR--AEKSNADFRDCTV-QHLQHSTRSADALRSP---------HRTNSLSPS-LHSNTKINGAHHSTVQGPSSTKSTS-VLTLSKVAPSVPSKPSDCNFISDFYSRSRLHHISTWKCELTEFVNTLQ--RQSSG--IFPGREKLKKVKTGRSSLVVTDTGTMSVLSSPRHQSCVMHVDMDCFFVSVGIRNRPDLKGKPVAVTSNRG---TGTAPLRPGANPQLEWQYYQNR---ALRGKAADIPDSSVWENQDSTQTNGIDS---VLSKAEIASCSYEARQVGIKNGMFFGYAKQLCPN---LQAVPYDFHACREVAQAMYETLASYTHS--IEAVSCDEALID--VTDILAETKLSPEEFAAALRIEIKDKT-KCAASVGIGSNILLARMATKKAKPDGQYHLQP-DEVDDFIRGQLVTNLPGVGRSMESKLAS--LGIKTCGDLQC-LTMAKLQKEFGPKTGQMLYRFCRGLDDRP-------VRTEKERKSVSAEINYGIRFTQPKEAEAFLLSLSEEIQRRLEAAGMKGKRLTLKIMVRKPGAPIETAKFGGHGICDNIARTVTLDQATDSAKIIGKATLNMFHTMKLNISDMRGVGIQVNQLVPANSNLSTCSSRPSAQSSLFSGRPHSVRDLFQLQKAKKPTEEEHKEVFLAAVDLEVSSTSRACGLLSPLSAHLAASVSPDTNSGECSRKWNGLHSPVSGQSRLNLSIEVPSPSQIDQSVLEALPLDLREQIEQVCAAQQGEPRG-KKKEPVNGCSSGVLPHPVGTVLLQIP-EPQEPCNSDSKISVIALPAFSQVDPDVFAALPAELQKELKAAYDQRQRQGEDTTHQQPTSTSVPKNPLLQLKPPAMKDKRNKRKNLIGSPRKSP--LKNKLLSSPAKTLPG---AYGSPQKLMDGFLQHEGMASERPLEEVSASTPGAQDLSSLLPG-QSSCFRPAAPNLAGAVEFSDVKTLLKEWITTIS---DPMEEDILQVVRYCTDLIEEKDLEKLDLVIKYMKRLMQQ--SVESVWN--MAFDFILDNVQVVLQQTYGSTLKVT---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBZ9-1", "uniprot_id": "REV1_HUMAN", "id": "Q9UBZ9-1", "name": "Translesion synthesis protein REV1", "aln": "----------------------MRRGGWRKRA-ENDGWETWGGYMAAKVQKLEEQFRSDAAMQ--KDGTSSTIFSGVAIYVNGYTDPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKAGRLLSYIPYQLYTKQSSVQKGLSFNPVCRPEDPLPGPSN-----------------IAKQLNNRVNHIVKKIETENEVKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGS--TAIFNGHTPSSNGALKTQDCLVPMVNSVASRLSPAFSQEEDK--AEKSSTDFRDCTL-QQLQQSTRNTDALRNP---------HRTNSFSLSPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHHISMWKCELTEFVNTLQ--RQSNG--IFPGREKLKKMKTGRSALVVTDTGDMSVLNSPRHQSCIMHVDMDCFFVSVGIRNRPDLKGKPVAVTSNRG---TGRAPLRPGANPQLEWQYYQNK---ILKGKAADIPDSSLWENPDSAQANGIDS---VLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPN---LQAVPYDFHAYKEVAQTLYETLASYTHN--IEAVSCDEALVD--ITEILAETKLTPDEFANAVRMEIKDQT-KCAASVGIGSNILLARMATRKAKPDGQYHLKP-EEVDDFIRGQLVTNLPGVGHSMESKLAS--LGIKTCGDLQY-MTMAKLQKEFGPKTGQMLYRFCRGLDDRP-------VRTEKERKSVSAEINYGIRFTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNIARTVTLDQATDNAKIIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPTNLNPSTCPSRPSVQSSHFPSGSYSVRDVFQVQKAKKSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPT--SPDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQPVGTVLLQIP-EPQE-SNSDAGINLIALPAFSQVDPEVFAALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTIGSPKRIQSPLNNKLLNSPAKTLPG---ACGSPQKLIDGFLKHEGPPAEKPLEELSASTSGVPGLSSLQSD-PAGCVRPPAPNLAGAVEFNDVKTLLREWITTIS---DPMEEDILQVVKYCTDLIEEKDLEKLDLVIKYMKRLMQQ--SVESVWN--MAFDFILDNVQVVLQQTYGSTLKVT---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GEY2-1", "uniprot_id": "A0AC58GEY2_DANRE", "id": "A0AC58GEY2-1", "name": "Translesion synthesis protein REV1", "aln": "MTRLAEGGGKPTPQLGQARSLSMSRDGWRKKASENDGWGGQGGYMAAKVSKLEEQFQKDAPREQKKDGKSSCIFSGVAIYVNGYTDPSAAELRRLMMLHGGQFHLYYSRSKTTHIIATNLPNFKIQELKGEKVVRPEWIIDSIKAGRQLSYIQYQLYAK----QKGLNFTRVSGIEGQDPSSNHGPDIKPQPSHTLSKDVLKSTQANHMANYTEKTDHQLDIRLRNGLHSIISEVDAEKSRVNGIHDDDDDDDIACSILPRGSQDTLLTNGHVHPVNGALKPQDFADHHPHVVDKASNQSHLPQDKYREGEEPCCSYTESKANSHLRSLISAASPAKQPGPHNMQTDLHQKPTSNSGTLGAPQKASLHDQTTVRLNGSYHVTSNSSTLANSSNQSGKSSAEAGIISEFFSHSRLHHISTWRNEFSEYVNSLQSRRRAAGGAVFSGREKLKKLKAN------CNSGSLMAAPQVR-QSCVLHVDMDCFFVSVGIRHRPDLIGKPVAVTSNRG---PGRVAQRPGANPQLEFQYYQNKQKHYRKEKTDGDLEMTPSPQDGEVPSNGVHEDLAALSMAEIASCSYEARQAGVRNGMFFGRAKQLCPD---LQSVPYDFHAYKEVALAMYEILASYTHN--IEALSCDEALVD--ATALLVELGVSPDELARSIREDIKEKT-GCCASVGMSSNILLARMATRKAKPKGQYLLRS-EEVDDFIRDQPVSSLPGVGRSMSSKLTS--LGVSTCGDLQQ-LSLSQLQREFGPRTGQTLFRFCRGLDDRP-------VRSEKERKSVSAEMNYNIRFTQVEEAESFLNNLSMEVQKRLEGAGLRGRRVTLKVMMRKPGAPVEPAKYGGHGICDNFARSVLLAQPTDSGRVIASEAIKLFHAMKLNVKDMRGVGLQVQQLDGSHADPSGQGPSRGRSIRDLLLAKQSAHSPSKESPSQDGLISASSSRAFSSNQKRVTPALSPPPSTSSSSSPPPSFTIIDPMPGTSKGDYHHPHTPNHVRACLNISIEVPSPSQVDPSVLKALPIDIRRQVEETWRYREEQPSTSSHYSTPPRPPS--TPPPGPSLVLQLPNQPGQPCTTG---IILELPDFSQVDPDVFAALPRELQEELCSAYRNK-----GNAQAQASTVVEQKNSFPQLKQPAVGKLKRRYKKRNTSPAKNG-------SSPLKKMFPGNSPAKTSPSKTLP-----------LPLREQDLKCP--SSLSTDVPETLPKPIPRPAPTLAGAHEFSEIRTLLREWVTTIS---EPMEEDILQVVKYCTELVEDKDLEKLYLVIKYMKRLMQQ--SSESVWS--MAFDFVLDNVQVVVQQTYGSTLKIT---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0P2-1", "uniprot_id": "REV1_DROME", "id": "Q9W0P2-1", "name": "DNA repair protein Rev1", "aln": "----------------------MTRD-------EDNGFSEWGGYFEAKKSKLEEQFAAASDPFR-----KSDLFQGISIFVNGRTDPSADELKRIMMVHGGTFHHYER-SHTTYIIASVLPDVKVRNMNLSKFISAKWVVDCLEKKKIVDYKPYLLYTNQKTSQPMLIFG---------------------------------KPKDNGANESKSDVEPPKDKAEVEVDSTKDETQMELG----------GILKN--------------------------------------------------------------------------------------------------LQQAVATSPEKEASASESKITNLSTTSNNS----------TTARTAADPNFLSEFYKNSRLHHIATLGAGFKQYVCRLRQKHGTQG---FPKRETLKSLANS---------------HHNCLERYVMHIDMDCFFVSVGLRTRPELRGLPIAVTHSKGGNAATDVPVHPQADRKAELELFAQR-----------FEHHFHDGDKAEKVRSGFDK---KMSLSEIASCSYEAREKGIRNGMFVGQALKLCPE---LKTIPYDFEGYKEVAFTLYDTVAQYTLN--IEAVSCDEMFVE--LTDLAHELNVDVMAFVSHLRQEVYSKT-GCPCSAGVAGNKLLARMATKEAKPNGQFLLDSSNDILAYMAPMSLDLLPGVGSSISHKLKQ--AGLNNCGDVQN-TTLEKMEKVLGKKLGQNLFQNCRGIDDRP-------LAYEQIRKTVSAEMNFGIRFTNSVECEQFLCQLSEEVTKRLVEIRRKARSINLKIMVRAAEAPVETSKYMGHGVCDIINKSSLIKYATDDVNVITTVVLDLMKDADIPPDELRGLGIHLTRLEDAN------EVRKENNIKEMFGKMSEMRKDKPIPQGAVGDKSIGDDKVNKPLVFENKPKPREPRNVLSMLTAAAVSRKSVTEDRSQRGTSKPITRPLSLVP------------KLDEDVLAQLPEDIRLEVIANREEHLCIAEYDGYRSP------------------QYPTLRSPP----------LLNPYVTTNVSPLKATDLKPSTSRAAVARLQKRKERKEQEHYIRSDQIVADYIDDLPDFVNPHILKLISHPVEMP---------ELLMG------------------------------------------------------------------------DNYKDLLNDWVSREE---VPKPNDVDLILKQVSRMIKNDQLDHVCDVMKYWCRIINMKRSSSCCWH--VAYKHIEESIQNQMLTIEGYSLLFIEYIRCIKCS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12689-1", "uniprot_id": "REV1_YEAST", "id": "P12689-1", "name": "Translesion synthesis protein REV1", "aln": "-------------------------------------MGEHGGLVDLLDSDLEYSINRETPDK------NNCLSQQSVNDSHLTAKTGGLNARSFLSTLSDDSLIEYVNQLSQTNKNNSNPTAGTLRFTTKNISCDELHADLGGGEDSPIARSVIEIQESDSNGDDVKKNTVYTR---------------------------EAYFHEKAHGQTLQDQILKDQYKDQISSQSSKIFKNCVIYINGYTKPGRLQLHEMIVLHGGKFLHYLSSKKTVTHIVASNLPLKKRIEFANYKVVSPDWIVDSVKEARLLPWQNYSLTSKLDEQQKKLDNCKTVNSIP------------LPSETSLHKGSKCVGSALLPVEQQSPVNLNN-------LEAKRIVACDDPDFLTSYFAHSRLHHLSAWKANLKDKFLNEN-------------IHKYTKITDK-------------------DTYIIFHIDFDCFFATVAYLCRSSS-------------------------------------------------FSACDFKRDPIVVCHGTKN-------SDIASCNYVARSYGIKNGMWVSQAEKMLPNGIKLISLPYTFEQFQLKSEAFYSTLKRLNIFNLILPISIDEAVCVRIIPDNIHNTNTLNARLCEEIRQEIFQGTNGCTVSIGCSDSLVLARLALKMAKPNGYNITFKSNLSEEFWSSFKLDDLPGVGHSTLSRLESTFDSPHSLNDLRKRYTLDALKASVGSKLGMKIHLALQGQDDEESLKILYDPKEVLQRKSLSIDINWGIRFKNITQVDLFIERGCQYLLEKLNEINKTTSQITLKLMRRCKDAPIEPPKYMGMGRCDSFSRSSRLGIPTNEFGIIATEMKSLYRTLGCPPMELRGLALQFNKLVDVG---------PDNNQLKLRLPFKTIVTNRAFEALPEDVKNDINNEFEKRNYKRKESGLTSNSLSSKKKGFAISRLEVNDLPS-----------------------------TMEEQFMNELPTQIRAEVRHDLR------------------------------------------------------------------IQKKIQQTKLGNLQEKIKRREESLQNEKNHFMGQNSIFQPIKFQNLTR-------------------------------------------------------------------------------------------------FKKICQLVKQWVAETLGDGGPHEKDVKLFVKYLIKLCDSNRVHLVLHLSNLISRELNLCAFLNQDHSGFQTWERILLNDIIPLLNRNKHTYQTVRKLDMDFEV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** . ..** .: : . : . : :.... : : :: .. . : . * .:. .:. : : : : . .: . . : * .. : . * : .. .. : .:::.:: .*****:: :.: . . .. ..: ::*:*:****.:*. *.. * .. ::****.* **. *::***:.. * :: *: * ::** *. : : ::*. : . * .:* ** . . : : :* :: . * * * * ... :***:* : ***.* : : : ***** * :* . . . .*:: :: :: .* : * :. :* **. **::* ::*:.***.: : : *: . : :* :.**:* * **:*..*: * * ** : :: : .*:. :* . .: : ::**:.::. :* . : . .. . . :: ..: ** ::* :: : . . : . . : : .. *:.:*:: * :*: .:: : ... :. : : : * :: . ::. : . : : ", "identical_positions": 103, "similar_positions": 236, "identity": "7.56%" }, { "cls_id": "homologset.agr.SGD:S000005874", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P11980-1", "uniprot_id": "KPYM_RAT", "id": "P11980-1", "name": "Pyruvate kinase PKM", "aln": "-------------------------------------------------------MPKPDSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVEMLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRAATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKEKGADY-LVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKVLG--EKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAVFHRLLFEELARASSQ-STDPLEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDAVLDAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14618-1", "uniprot_id": "KPYM_HUMAN", "id": "P14618-1", "name": "Pyruvate kinase PKM", "aln": "-------------------------------------------------------MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADF-LVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLG--EKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPI-TSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HSQ3-1", "uniprot_id": "A0AC58HSQ3_DANRE", "id": "A0AC58HSQ3-1", "name": "Pyruvate kinase", "aln": "--------------MGSGSSSS-----------------GGAVVESRILPVSSTMSQTKAQDMGSAFIQTQQLNAAMADTFLEHMCLLDIDSEPTIARNTGIICTIGPASRSVDTLKEMIKSGMNIARMNFSHGSHEYHGETIKNVREACASFEPGSIQYRPVGIALDTKGPEIRTGLIKGSGTAEVELKKGNKIKVTLDDSFMENCDEDTLWLDYKNITKVVEVGSKVYIDDGLISLQVLQIGSDY-LICEIENGGSLGSKKGVNLPGAAVDLPAVSEKDIKDLQFGVEMGVDMIFASFIRKAADVQAVRKVLG--EKGKNIKIISKLENHEGVRRFDEIMEASDGIMVARGDLGIEIPTEKVFLAQKMMIGRCNKAGKPIICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRTQHMIAREAEAATFHRQLFEGLRRSSVL-TRDPSDAVAVGAVEASFKCCASGIIILTKTGRSAHLISRYRPRAPILAVTRNEQTARQAHLYRGIFPIYYNSPSNDVWAEDVDLRVNFAMDVGKARGFFKAGDVVIVLTGWRPGSGYTNTMRVVPVP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BA79-1", "uniprot_id": "A0A8M2BA79_DANRE", "id": "A0A8M2BA79-1", "name": "Pyruvate kinase", "aln": "MFNCEVNPVLAEERIAVGSSSGRYRVDKLRQWRMKSSEVPAGVHQQRTLLADAAPAMSQTKTTASGFIQTQQMPAAMAETFLEHLCLLDIDSEPTVSRNTGIVCTLGPASRSLETLREMILSGMNVARLNFSHGTHEYHAETIKSVREAIESFGAGTIDYRPVAIALDTKGPEIRTGLIKGSGTEEVKLVKGNIIKLTLDDKFMDNCDENTLWLDYKNITKVVQQGSHIYVDDGLISLKVKEIGSDF-LNCEIENGGMLGSKKGVNLPGANVDLPAVSEKDIKDLQFGVEQGVDMVFASFIRKAADVHAVRKVLG--EKGKDIRIISKLENHEGVRKFDEILEASDGIMVARGDLGIEIPTEKVFLAQKMMISRCNRIGKPIICATQMLESMIKKPRPTRAESSDVANAVLDGADCIMLSGETAKGEYPIESVLTQHLIAREAEAAMFHRQLFEELRRTSHL-TRDPTESVAVGAVEASFKCCASAIICLTKTGRSAQLLSRYRPRAPIMAVTRNGQTSRQLHLYRGVIPILYTKPANDIWAEDVDLRVSFALEIGKHRKYFKSGDVIIVVTGWRPGSGYTNTMRIVVVP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P12928-1", "uniprot_id": "KPYR_RAT", "id": "P12928-1", "name": "Pyruvate kinase PKLR", "aln": "------------MSVQENTLPQQLWPWIFRSQKDLAKSALSGAPGGPAGYLRRASVAQLTQELGTAFFQQQQLPAAMADTFLEHLCLLDIDSQPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANIREATESFATSPLSYRPVAIALDTKGPEIRTGVLQGGPESEVEIVKGSQVLVTVDPKFQTRGDAKTVWVDYHNITRVVAVGGRIYIDDGLISLVVQKIGPEG-LVTEVEHGGILGSRKGVNLPNTEVDLPGLSEQDLLDLRFGVQHNVDIIFASFVRKASDVLAVRDALG--PEGQNIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKARPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVMMQHAIAREAEAAVYHRQLFEELRRAAPL-SRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSQYRPRAAVIAVTRSAQAARQVHLSRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSVS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53657-1", "uniprot_id": "KPYR_MOUSE", "id": "P53657-1", "name": "Pyruvate kinase PKLR", "aln": "------------MSVQENELPQQLWPWIFKSQKDLAKSALSGAPGGPAGYLRRASVAQLTQELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANIREAAESFATSPLSYRPVAIALDTKGPEIRTGVLQGGPESEVEIVKGSQVLVTVDPKFRTRGDAKTVWVDYHNITQVVAVGGRIYIDDGLISLVVRKIGPEG-LVTEVEHGGFLGNRKGVNLPNAEVDLPGLSEQDLLDLRFGVEHYVDIIFASFVRKASDVVAVRDALG--PEGRGIKIISKIENHEGVKKFDEILEVSDGIMMARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKARPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPL-SRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLSRGVFPLLYREPPEAVWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLTIS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30613-1", "uniprot_id": "KPYR_HUMAN", "id": "P30613-1", "name": "Pyruvate kinase PKLR", "aln": "------------MSIQENISSLQLRSWVSKSQRDLAKSILIGAPGGPAGYLRRASVAQLTQELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEG-LVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALG--PEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPL-SRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O62619-1", "uniprot_id": "KPYK_DROME", "id": "O62619-1", "name": "Pyruvate kinase", "aln": "----------------------------------------------------MVNVTIYDEAPQLKPNEVPQNMAAGADTQLEHMCRLQFDSPVPHVRLSGIVCTIGPASSSVEMLEKMMATGMNIARMNFSHGSHEYHAATVANVRQAVKNYSAKLGYEHPVAIALDTKGPEIRTGLIGGSGTAEIELKKGEKIKLTTNKEFLEKGSLEIVYVDYENIVNVVKPGNRVFVDDGLISLIVREVGKDS-LTCEVENGGSLGSRKGVNLPGVPVDLPAVSEKDKSDLLFGVEQEVDMIFASFIRNAAALTEIRKVLG--EKGKNIKIISKIENQQGMHNLDEIIEAGDGIMVARGDLGIEIPAEKVFLAQKAMIARCNKAGKPVICATQMLESMVKKPRPTRAEISDVANAVLDGADCVMLSGETAKGEYPLECVLTMAKTCKEAEAALWHQNLFNDLVRGAG--TIDASHAAAIAAVEAATKAKASAIVVITTSGKSAFQVSKYRPRCPIIAVTRFAQTARQAHLYRGLVPLIYKEPGLGDWLKDVDVRVQFGLQVGKKNGFIKTGDSVVVVTGWKQGSGFTNTIRIVTVE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52489-1", "uniprot_id": "KPYK2_YEAST", "id": "P52489-1", "name": "Pyruvate kinase 2", "aln": "----------------------------------------------------------------------------MPESRLQRLANLKIG-TPQQLRRTSIIGTIGPKTNSCEAITALRKAGLNIIRLNFSHGSYEFHQSVIENAVKSEQQFPG-----RPLAIALDTKGPEIRTGRTLN--DQDLYIPVDHQMIFTTDASFANTSNDKIMYIDYANLTKVIVPGRFIYVDDGILSFKVLQIIDESNLRVQAVNSGYIASHKGVNLPNTDVDLPPLSAKDMKDLQFGVRNGIHIVFASFIRTSEDVLSIRKALG--SEGQDIKIISKIENQQGLDNFDEILEVTDGVMIARGDLGIEILAPEVLAIQKKLIAKCNLAGKPVICATQMLDSMTHNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGDYPVNAVNIMAATALIAESTIAHLALYDDLRDATPK-PTSTTETVAAAATAAILEQDGKAIVVLSTTGNTARLLSKYRPSCPIILVTRHARTARIAHLYRGVFPFLYEPKRLDDWGEDVHRRLKFGVEMARSFGMVDNGDTVVSIQGFKGGVGHSNTLRISTVGQEF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VQH0-1", "uniprot_id": "Q9VQH0_DROME", "id": "Q9VQH0-1", "name": "Pyruvate kinase", "aln": "------------------------------------------------------------------MSLSAKSVLKEGSTQLSHICELDLAQQASHQRLVSLIATISVSSRNADTIYTMIMRGVNIFRLNFSHESHEMHSKTIELINEALERIHKETGQIRTVAIAADTRGPQIRTGLLDG----DVFLRSGDNLRLSINRDLYDKGNKEAVYVDYPNIINLTKTGDRLFIDDGRLLLHILEVGVDG-LLCEVIHGGQLNNNCNVILPEIEIDLPAVSEKDMFDIQFSIKANVDFLFASAVRSAKNVKELRTVLG--EKGKHIKIIAKMDSKIALSRFSEILRAADGLLLSRADLGTQIPIEKLFITQKSILGQCNKVGKPVIVASHILESMRTLPHPTRAECFDLANAIIDGADCIMLSSEVAIGSFPKETVATCDTLCREAEKVLWFRDLFSDLVSEVRG-ELDAAHSLAIAAVETAKRTNATLIIVLTTSGRSATLVSKFRPRCPIMAITRCERTARWVYLHRGVLPILYTLEPSTDYATDVDARVQFAMTSAKKWGIIDDGDPIVIVSAWKDGGGFTNNVRVVYAFFEADRVDCLFRSDRRHSRKNTNLQMANREPADKKSGNA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFG4-1", "uniprot_id": "Q9VFG4_DROME", "id": "Q9VFG4-1", "name": "pyruvate kinase", "aln": "---------------------------------------------------------------MEPKKFRLDRG--PYLSQLDYQSRLQFQAPALRLPLTSIICTIGPSSSQPEVLLNLIHAGMKVVRLDFSDGTHDCHCQAIQAAR----------------------------------------------------------KAIA--MYAEETGLPRSLA--------------IALDTKG-----------------PVINPQGVAADLNAITEQDKLDLKFGADQKVDMIFASFIRDAKALKEIRQALGACPSSEHIKIISKIESQQALANIDEIIRESDGIMVALGNMGNEIALEAVPLAQKSIVAKCNKVGKPVICANQMMNSMITKPRPTRAESSDVANAILDGCDALVLSDETAKGKYPVQCVQCMARICAKVESVLWYESIQNNLKSEVRINAADHISAVSTAIAEAATVSQAQAIVVASPCSIVSQMVSQMRPPCPIVLLTGCPHEAAQSLLFRGVYPLLVKEMVYGSVNYCRIMQSGLKILAKLDILKAGQRGTLVLVNAMSADKLTFRLFTFAQPTEAERE-EERCRKLARKQRCKEMSVNKSCPNPKSSKSEISIKSDEKDGTSSKKEFPKDEEVSKCLQLENEIQQKRGEDSVMNKENENLCHNVALKCLHLKNERQAQSEAMMKQTEKLKKAEDPRK--NNGTLKDSFNRKKKDDKTSKSDKKDGSSSKKDRPNHKEVWKCLQRSQDLVMAEENEYLCSKKSKECPNKDDEALKCLQLKKQRQARAEAEMKKKAELKKNNSLSHKKEDDKAPNCNKLKKQGPKKNKCRVVKISRTSEKDNYIPKKEYPRIFNIEKAQPKTVVKHSKELAKSCDIVLENCKTVKRKNCKTVKLEKCKTVKLENCKITKLKKCKTIKLENCKQPRRVRQRTNLTKKA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VD23-1", "uniprot_id": "Q9VD23_DROME", "id": "Q9VD23-1", "name": "Pyruvate kinase", "aln": "---------------------------------------------------------------MRVVRMNFSHGSHEYHCQTIQAARKAIAMYVEQTGLPRTLA-IALDTKGPEIRTGKLAGGNDRAEIELKTGDKVTLSTKKEMAD----------------------------------------------------------KSNKDNIYVDYQRLPQLVKPGNRVFVDDGLIALIVKESKGDE-VICQVENGGKLGSHKGINLPGVPVDLPSVTEKDKQDLKFGAEQKVDMIFASFIRDANALKEIRQVLG--PAGACIKIISKIENHQGLVNIDDIIRESDGIMVARGDMGIEIPTEDVPLAQKSIVAKCNKVGKPVICATQMMESMTNKPRPTRAEASDVANAIFDGCDAVMLSGETAKGKYPVECVQCMARICAKVEAVLWYESLQNSLKREIRTSAADHISAVTTAIAEAATVGQARAIVVASPCSMVAQMVSHMRPPCPIVMLTGNESEAAQSLLFRGIYPLLVEEMVIGSFNFRRIMQSGLKLMGKMDILEPGQKGSVVLVNAMSAEKITFRLFTIRQQTKEERDQDERCRKLALEQSCKERAEKEECRKLQ--------QAEECQKQKLAKKCKQFEEKQKVCPKKNDTPKNDCPKKDCPKKECPKQDDEISKCRQMQEAEAEERKCKEEFEQMCKLAEEKRKEAEKCRKADEERRKEEAEKCRKLEEDRKCKLAEEKKRNEEELKIIEAEVAKLEAAEK----AKRLKEEEKKKEELMKCKQRNEAKKKREEAERCKRKER----------ERELAEMENKWKQVAEKRKRKKAAEMCR-----------------KIEDAKEKAAAESADKILK----------------------AVCEKLKQSLSDPDKSKKGKK----------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : :. : : * . .:::. :: : : . . : ** :: :* *: *. :.::*** :* : : :* .** . *:**:*::.: .: .:.:*:. **:::: .::* :* : ** ::.:** ***:: *.::::** .:***** *:.**::**.*.::**.*.* *.:* : * . .* . . : . * . : . . : . :: : . : ::: ** ..:: :* : * **: *. : : : . :: : . . . . ", "identical_positions": 59, "similar_positions": 123, "identity": "6.2%" }, { "cls_id": "homologset.agr.SGD:S000005875", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TBB6-1", "uniprot_id": "S7A14_HUMAN", "id": "Q8TBB6-1", "name": "Solute carrier family 7 member 14", "aln": "---------MSGFFTSLDPRRVQW----GAAWYAMHSRILRTK--PVESMLEGTGTTTAHGTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAVWVFIMIAGLFFINGKYWAEGQ--FLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVKFLSEEHTKKKEGILADCEKEACSPVSEGDEFSGPATNTCGAKNLPSLGD-------NEMLIGKSDKSTYNVNHPN--YGTVDMTTGIEADESENIYLIKLKKLIGPHYYTMRIRLGLPGKMD--RPTAATGHTVTICVLLLFILMFIFCSFIIFGSDYISEQSWWAILLVVLMVLLISTLVFVILQQPENPKKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVWCFVGLLIYFGYGIWNSTLEIS---------------------------------AREEALHQSTYQRYDVDDPFS---VEEGFSYATEGESQEDWGGPTED---KGFYYQQMSDAKANGRTSSKAKSKSKHKQNSEALIANDELDYSPE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZSU3-1", "uniprot_id": "D3ZSU3_RAT", "id": "D3ZSU3-1", "name": "", "aln": "---------MSGFLSSLDPRRVQW----GAAWYAMHSRILRTK--PVESMLEGTGATSAHGTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMVDTVGTLNGLGKGEESYPDLLALVIAVIVTIIVALGVKNSVGFNNVLNVLNLAVWVFIMIAGLFFVNGKYWAEGQ--FLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSMILTLMVPYYAIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLSLLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVKFLSEEHTKKKEGILADCEKETCSPVSEGEEFSSPATNTCGAKNLPSLGD-------NEMLIGKSDKSAYNVNHPN--YGTVDMTTGIEADESENIYLIKLKKLIGPRYYTMRIRLGLPGKMD--RPTAATGHTVTICVLLLFILMFIFCSFVIFGSEYISGQSWWAILLVVLMLLLITVLVFVILQQPENPKKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVWCFVGMLIYFGYGIWNSTLEIS---------------------------------AREQALHQSTYQRYDVDDPFS---VEEGFSYATEGESQEDWGGPAED---KGFYYQQMSDAKANSRTSSKAKSKSKHKQNSEALIENDELDCSPE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VWD3-1", "uniprot_id": "Q9VWD3_DROME", "id": "Q9VWD3-1", "name": "Cationic amino acid transporter C-terminal domain-containing protein", "aln": "-------MKPSDLLLVLEKVKFRVPLPPGVSSTTLLPKLIRTK--DVKQLQDGN--AQPQKPKLTKCLNTLDLTSLGIGSCCGTGMYLVAGMVAQKIAGPGVIISFIIAAIASIFSGACYAEFGVRVPHTSGSAYMYSYVAVGEFVAFIIGWNMILEYLIGTSACACALSSSFDSLTGNAIARTISESIGTIFGKP------PDFIAFGITLLMTCVLAMGASKSVIFNHSLNAVNLATWVFVMAAGLFYVDTKTWSEHQG-FLPYGWSGVFSGAATCFYAFIGFDIIATTGEEAHNPQKSIPKAIVGSLVVVLIAYVSVSLVLTLVVPYDHINTGAALVQMWSYVNAPKCRAVVAIGATAGLSVAMFGSMFPMPRVIYAMAQDGLIFRQLSQLWHRTNVPGLATIGSGLAAALVALTVRLEILVEMMSIGTLLAYTLVSTCVLVLRYQPHS--TSLVELLPAQLRTPVAHGTASDSRSHVTPA-EVLEVPGKLTIKRVTRGMSDSDDSFIDDSPEGFLGGRDDQFLVSDRSENKFYGSVHGAPTGPTGQATAFDAMGLNFVTRKIHDYAYLCPGFFPWINPGQATAESGMYVTKLVGIMFGLIFFLDLFAAIG---WSGG--LAAFIYFILFIGIFVILLIISRQPQNRYALAFLTPGLPFIPAIAITVNIYLIFKLSILTLVRFTVWMSLGFIMYFYYGITHSSLEQASDDLELHVDYSKNVEEKAVWDQQSYNQTHEPVWASKEVKQPSTEQRYNYGKTTSSSSSAQGSSRSGQGSAPEKPAGRSTAGLNRPVPPPPIAGQAKGSGSGSGPPMERQYTGQFSMFVDEGQFPTWDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B5DFJ0-1", "uniprot_id": "B5DFJ0_RAT", "id": "B5DFJ0-1", "name": "", "aln": "------------MARGLPS---------TARLARFCQKLNRLK--PLE--------ESSTETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGTVAKDMAGPAVLLSFLVAAVASLLAALCYAEFGARVPRTG-SAYLFTYVSMGEIWAFLIGWNVLLEYLIGGAAVARAWSGYLDAIFNHSIRNFTESHMGVWQMPFLA--HYPDFLAAGILLVASAFVSCGARVSSWLNHTFSAISLIVILFIIVLGFILARPHNWSAEEGGFAPFGFSGILAGTATCFYAFVGFDVIAASSEEAKNPRWAVPMAIAISLGLAAGAYILVSTVLTLMVPWHSLDPDSALADAFYRRGYGWAGFIVAVGSICAMNTVLLSNLFSLPRIVYAMAADGLFFQVFARVHPRTQVPVVGILVFGVLMALLALLMDLEALVQFLSIGTLLAYTFVATSIIVLRFQKAS-----------------------------PPSSPCPASPGPTVKKY---------------------------------------------------DSFSDHIQLVDAVQASMSEPGQLRPALKPFLG-FLDGLSPGTAVTWALGILIASAISLACVLVFGNSALHLPRWGYVLLLVVSGAVFLSSLLVLGAHQQQKKQDTFQIPLVPLTPALSILLNLCLMLKLSYLTWLRFIFWLLVGLVVYFGYGIWHSKENQR----------------------------------EPLELTTAHYVVFPSGS---------------------------------------LEETVQAVQPDSQTPVQGPGCTE---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLQ7-1", "uniprot_id": "CTR4_MOUSE", "id": "Q8BLQ7-1", "name": "Cationic amino acid transporter 4", "aln": "------------MARGLPS---------TACLARFCQKLNRLK--PLE--------ESSMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGTVAKDMAGPAVLLSFLVAAVASLLAALCYAEFGARVPRTG-SAYLFTYVSMGEIWAFLIGWNVLLEYLIGGAAVARAWSGYLDAIFNHSIRNFTESHLGVWQVPFLA--HYPDFLAAGILLVASAFVSCGARVSSWLNHTFSAISLIVILFIIVLGFILARPHNWSAEEGGFAPFGFSGILAGTATCFYAFVGFDVIAASSEEAKNPRWAVPMAIAISLSLAAGAYILVSTVLTLMVPWHSLDPDSALADAFYRRGYSWAGFIVAVGSICAMNTVLLSNLFSLPRIVYAMAADGLFFQVFARVHPRTQVPVVGILVFGVLMALLALLLDLEALVQFLSIGTLLAYTFVATSIIVLRFQKAS-----------------------------PPSSPCLASPGPTAKKY---------------------------------------------------DSFSDHIQLVGAEQTSMSEPGQLRPALKPFLG-FLDGCSPGTAVAWALGILVASAISLACVLVFGNSDLHLPQWGYVLLLVISGAVFLSSLLVLGAHQQQKKQDTFQIPLVPLTPALSILLNTCLMLKLSYLTWLRFIFWLLVGLVVYFGYGIWHSKENQR----------------------------------EPLELTTAHYVVFPSGS---------------------------------------LEETVQAVQPSSQSPVRESGCTE---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43246-1", "uniprot_id": "CTR4_HUMAN", "id": "O43246-1", "name": "Cationic amino acid transporter 4", "aln": "------------MARGLPT---------IASLARLCQKLNRLK--PLE--------DSTMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAVLLSFGVAAVASLLAALCYAEFGARVPRTG-SAYLFTYVSMGELWAFLIGWNVLLEYIIGGAAVARAWSGYLDSMFSHSIRNFTETHVGSWQVPLLG--HYPDFLAAGIILLASAFVSCGARVSSWLNHTFSAISLLVILFIVILGFILAQPHNWSADEGGFAPFGFSGVMAGTASCFYAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKSS-----------------------------PPSSPGPASPGPLTKQQ---------------------------------------------------SSFSDHLQLVGTVHASVPEPGELKPALRPYLG-FLDGYSPGAVVTWALGVMLASAITIGCVLVFGNSTLHLPHWGYILLLLLTSVMFLLSLLVLGAHQQQYREDLFQIPMVPLIPALSIVLNICLMLKLSYLTWVRFSIWLLMGLAVYFGYGIRHSKENQR----------------------------------ELPGLNSTHYVVFPRGS---------------------------------------LEETVQAMQPPSQAPAQDPGHME---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P15380-1", "uniprot_id": "PUT4_YEAST", "id": "P15380-1", "name": "Proline-specific permease", "aln": "MVNILPFHKNNRHSAGVVTCADDVSGDGSGGDTKKEEDVVQVTESPSSGSRNNHRSDNEKDDAIRMEKISKNQSASSNGTIREDLIMDVDLEKSPSVDGDSEPHKLKQGLQSRHVQLIALGGAIGTGLLVGTSSTLHTCGPAGLFISYIIISAVIYPIMCALGEMVCFLPGDGSDSAG-STANLVTRYVDPSLGFATG----WNYFYCYVILVAAECTAASGVVEYWTTAVPKGVWITIFLCVVVI-LNFSAVKVYGESEFWFASIKILCIVG---LIILSFILFWGGGPNHDRLGFRYWQHPGAFAHHLTGGSLG-NFTDIYTGIIKGAFAFILGPELVCMTSAECADQRRNIAKASRRFVWRLIFFYVLGTLAISVIVPYNDPTLVNALAQGKPGAGS---SPFVIGIQNAGIKVLPHIINGCILTSAWSAANAFMFASTRSLLTMAQTG---------------------------------QAPKCLGRINKWG------------------------------------------------------VPYVAVGVSFLCSCLAYLNVSSSTADVFNWFSNISTISGFLGWMCGCIAYLRFRKAIFYNGLYDRLPFKTWGQPYTVWFSLIVIGIITITNG-YAIFIPKYWRVADFIAAYITLPIFLVLWFGHKLYTRTWR---QWWLPVSEIDVTTGLVEIEEKSR--------------------------------------------------------------------------------------------EIEEMRLPPTGFKDKFLDALL---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . . : : : . * : : : .: * . .: . : . . . . *: .: . * : :::* :: : . . . .. . . : . :. : : : :: : : . . . . : : : :: : : :. : * . :. : :*: * ... :. * *:. * . .. :: : . * :. . :: : .:. : . * :.. ::: : . : *. * : : : : * : :.: :* . . : . :. . : : : . . : : :. ::.: : : ** * * : . *: . : . : . ", "identical_positions": 22, "similar_positions": 146, "identity": "2.63%" }, { "cls_id": "homologset.agr.SGD:S000005876", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZJB6-1", "uniprot_id": "A0A8I5ZJB6_RAT", "id": "A0A8I5ZJB6-1", "name": "Tubulin-specific chaperone D", "aln": "MVLSNEPAASAAEEEVEDDALVRASTLEAFGESAETRALLRSLPAVHRERAAREVAEERFRVIMDKYQEQPHLLDPHLEWMMNSLLDIVQDETSLPDLVHLAFKFLYIITKVRGYKVFLRLFPHEVADVQPVLDMFTGQNPKDHETWETRYMLLLWLSVTCLIPFDFSRLDGNLPTQSG-----------ETRMPIMDRILQIAQSYLVVSDKARDAAAVLVSKFITRPDVKQRKMASFLDWSLCTLAHSSFQTIDGVITMDGMLQALAQIFKHGKREDCLPYANTVLQCLDGCRLPESSHTLLRKLGVKLVQRLGLTFLKPKVATWRYQRGCRSLAANLQLRAPGKSEQKLLSDSLTSDGDEDYDVPEGVETVIEQLLVGLKDKDTIVRWSAAKGIGRMAGRLPRELADDVVGSVLDCFSFQETDKAWHGGCLALAELGRRGLLLPSRLSEVVTVILKALTYDEKRGACSVG-ANVRDAACYVCWAFARAYEPQELTP-FVTAISSALVIAAVFDRNVNCRRAASAAFQENVGRQG-TFPHGIDILTTADYFAVGNISNCFLIISVFIAGFQEYTKPMIDHLVSMKIN-HWDGAIRELSAKALHNLTSLVPEYMATHVFPALLLMTQSPDLHTRHG--AILACAEVTYALYELAAQSNRLVTDYLDEKAVQSLKQIHQQVCVS--YKSLFGKIMCCFFSFSFSIVCILIEKLSLSRMPFKGDTVIEGWQWLINDTLRSLHLVSSHSREQIKHCPG--LPVMR-----QRPLLNTSFFPEELIPQYLAELR-SPEEMTRCGFSSALGALPC--FLLRGHLQQVLSGLRRVTCTTSPMDVS-------------FAEARRDGLKAISRICQTVGVNTQGPPDEVICQENISEVYAALLGCMSDYTTDSRGDVGAWVREASMTSLMDLMLLLAQTEPVLIEAHICERVMCCVAQQASEKIDRFRAHAARVFLTLLHFDSPPIPHVPHRKELESLFPRSDVATVNWNAPSQAFPLITQLLGLPTYRYHVLLG-LAVSVGGLTESTVRHSTQSLFEYMKGIQKDAQVLESFSETLLKVFEDNLLNDRVSVSLLKMLDQLLANGCFDIFTAEENHPFCVKLLTLCKEEIKKSKDIQKLRSSIAVLCGMVQFSGDVRKKVLLQLFLLLGHPFPVIRKSTASQVYEMVLTYSDLVDA--EVLDEVMSVLSDTAWDSELPVVRGQRNHLCDLLGVPRPQLVPKVILVVVPVLPVVLSSGLK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BYA0-1", "uniprot_id": "TBCD_MOUSE", "id": "Q8BYA0-1", "name": "Tubulin-specific chaperone D", "aln": "MVLSNEPAASAAEEEVEDDALVRASALEAFGESAETRALLRSLPAVHRERASREVAEERFRVIMDKYQEQPHLLDPHLEWMMNSLLDLVQDETSLPDLVHLAFKFLYIITKVRGYKVFLRLFPHEVANVQPVLDMFTGQNPKDHETWETRYMLLLWLSVTCLIPFDFSRLDGNLSTQTG-----------ETRVPTMDRILQIAESYLVVSDKARDAAAVLVSKFITRPDVKQRKMASFLDWSLCTLAHSSFQTIEGVITMDGMLQALAQIFKHGKREDCLPYANTVLQCLDGCRLPESSHTSLRKLGVKLVQRLGLTFLKPKVATWRYQRGCRSLAANLKLCAPGKSDQKLLSDSLTSDGDEDYDVPEGVETVIEQLLVGLKDKDTVVRWSAAKGIGRMAGRLPRELADDVVGSVLDCFSFQETDKAWHGGCLALAELGRRGLLLPSRLSEVVTVILKALTYDEKRGACSVG-ANVRDAACYVCWAFARAYEPQELTP-FVTAISSALVIAAVFDRNVNCRRAASAAFQENVGRQG-TFPHGIDILTTADYFAVGNISNCFLIISVFIAGFQEYTKPMIDHLVSMKIN-HWDGAIRELSAKALHNLTPQVPEYIAMHVFPALLLMTQSPDLHTRHG--AILACAEVTYALYKLATQSNRLVTDYLDEKAVQSLKQIHQQLCDRHLYRGLGGELMR-------QAVCILIEKLSLSRMPFKGDATVEGWQWLINDTLRSLHLVSSHSRQQIKEVAVSALTALCSEYYVKEPGEAGSSIAKELIPQYLAELQ-SPEEMARCGFSSALGALPG--FLLRGHLQQVLSGLRRVTCIS-PNDVS-------------FAEARRDGLKAISRICQTVGVNTRGPPDEVICKENISEVYAALLGCMSDYTTDSRGDVGAWVREAAMTSLMDLMLLLARTEPVLIEAHICERVMCCVAQQASEKIDRFRAHAARVFLTLLHFDSPPIPHVPHRQELESLFPRSDVATVNWNAPSQAFPLITQLLGLPTYRYHVLLG-LAVSVGGLTESTVRHSTQSLFEYMKGIQKDAQVLQSFSETLLKVFEDNLLNDRVSVSLLKMLDQLLANGCFDIFTAEENHPFCVKLLTLCKEEIKKSKDIQKLRSSIAVLCGMVQFNGDVRKKILLQLFLLLGHPFPVIRKSTASQVYEMVLTYSDLVDA--EVLDEVMSVLSDTAWDAELPVVREQRNRLCDLLGVPRPQLVPKPIPGS-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BTW9-1", "uniprot_id": "TBCD_HUMAN", "id": "Q9BTW9-1", "name": "Tubulin-specific chaperone D", "aln": "MALSDEPAAGGPEEEAEDETLAFGAALEAFGESAETRALLGRLREVHGGGAEREVALERFRVIMDKYQEQPHLLDPHLEWMMNLLLDIVQDQTSPASLVHLAFKFLYIITKVRGYKTFLRLFPHEVADVEPVLDLVTIQNPKDHEAWETRYMLLLWLSVTCLIPFDFSRLDGNLLTQPG-----------QARMSIMDRILQIAESYLIVSDKARDAAAVLVSRFITRPDVKQSKMAEFLDWSLCNLARSSFQTMQGVITMDGTLQALAQIFKHGKREDCLPYAATVLRCLDGCRLPESNQTLLRKLGVKLVQRLGLTFLKPKVAAWRYQRGCRSLAANLQLLTQGQSEQKPL--ILTEDDDEDDDVPEGVERVIEQLLVGLKDKDTVVRWSAAKGIGRMAGRLPRALADDVVGSVLDCFSFQETDKAWHGGCLALAELGRRGLLLPSRLVDVVAVILKALTYDEKRGACSVG-TNVRDAACYVCWAFARAYEPQELKP-FVTAISSALVIAAVFDRDINCRRAASAAFQENVGRQG-TFPHGIDILTTADYFAVGNRSNCFLVISVFIAGFPEYTQPMIDHLVTMKIS-HWDGVIRELAARALHNLAQQAPEFSATQVFPRLLSMTLSPDLHMRHG--SILACAEVAYALYKLAAQENRPVTDHLDEQAVQGLKQIHQQLYDRQLYRGLGGQLMR-------QAVCVLIEKLSLSKMPFRGDTVIDGWQWLINDTLRHLHLISSHSRQQMKDAAVSALAALCSEYYMKEPGEADPAIQEELITQYLAELR-NPEEMTRCGFSLALGALPG--FLLKGRLQQVLTGLRAVTHTS-PEDVS-------------FAESRRDGLKAIARICQTVGVKA-GAPDEAVCGENVSQIYCALLGCMDDYTTDSRGDVGTWVRKAAMTSLMDLTLLLARSQPELIEAHTCERIMCCVAQQASEKIDRFRAHAASVFLTLLHFDSPPIPHVPHRGELEKLFPRSDVASVNWSAPSQAFPRITQLLGLPTYRYHVLLG-LVVSLGGLTESTIRHSTQSLFEYMKGIQSDPQALGSFSGTLLQIFEDNLLNERVSVPLLKTLDHVLTHGCFDIFTTEEDHPFAVKLLALCKKEIKNSKDIQKLLSGIAVFCEMVQFPGDVRRQALLQLCLLLCHRFPLIRKTTASQVYETLLTYSDVVGA--DVLDEVVTVLSDTAWDAELAVVREQRNRLCDLLGVPRPQLVPQPGAC--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQ78-1", "uniprot_id": "Q9VQ78_DROME", "id": "Q9VQ78-1", "name": "Tubulin-specific chaperone D", "aln": "--------MSNSVEECKDEDLP-ANTLEHFTELQQVLEMIDNIKSIAANTFEREF--EQYAQVLSRYQEQPHLLDPHLEELLGKLLHKIRKPDLDTGELHAAFKYLYIICKVRTYKVLVKFMPHELSDLEFVLDLLGQQNPKEFEQWETRYILLLWMSILVLNPFHMSRLDAYDTSTSAPTTNCSPVNHVQSKNTKMDRIFELIQLYVSSNDTCSSMAAFLAAKYFIRSDIKDLYLERFLDWIMEQHQADTLN------VKFGQLAAVAAILKHGKREDLLPYADKLLQWITSCQYKDDNDFLKYKNYVKIIQRIGLVHLKPRIASWRYKRGTRSLATNLNQTTAAGGEPVVLEQSLEEG--EEIVVPDAIEEVIEELLQALRSGGNDIRWSAAKGLGRVTNRLPKELADEVIGSVIDILNPLEPHEAWHGACLALAELAKRGLLLPHRLEELVPLLMQALFYDEMKGYMSVG-QHIRDSACYMCWAFARAYNPDDVKP-FVHKISSGLLTVAVFDREVNCRRAASAAFQESVGRLG-NFPFGIEISTTTDFYSVGIRQNSYLNISDYIAQFEVYREPLINHLVQHKVS-HWDSAIRELTAKALHKLSLWEPEYMAAVVLPQLLAKTDTIDINCRHG--CVLAMGEITLTLRKLEEKSD-PQVVYLSNQRVAELNELIITFLDKNFYRGMSGDLMK-------SCTSSYIKNCSLAKLQATPECLVS-WQKVIDS-----CLITKSN--AIRDGAVEAFGELCTTYYCSDSRHGE---NEAIINTYLTGADNDLEEHIRMGYIAALGVLPS--FMIRCHLQAILDSLVKHSLTPLQAVLVGEMGDRENIQAYRWSEARTQSVLALTKLVKTVGYGG--GIDSFAEPKNFNKVIECLLRALQEYTLDNRGDIGAWVREAAMSSLYEIVTTCP---PDLLAPEQVHEIVVGFMQQAVEKIDRTRGLGGRLCCQLIHH-QPRIPYIREHSKLLEIFP-ADADSVLWLFADHTFPLFCELLSLPDYSKRVLLG-LSASIGQLTESLIKYASSALFHFLR---SNPETVPRLCSEVVQIFEEHLLNERVTYPLLSFLDILIGSGTVESVLHDEANPFAEDIFRLLNLEVKGYKKLYKTATSISAFCQLLQVP-RLSKRILSKLSVFLGLQHVHVRKTAATKLYEALALHGDVTEVPEENMDEILTLLSETDWTQPLVEVRPLRNQLCQLMDIKPPVSGAAAAAALQQASADK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40987-1", "uniprot_id": "CIN1_YEAST", "id": "P40987-1", "name": "Chromosome instability protein 1", "aln": "--------------------------------MNNIRALLDSIQSGVQTVSPEKH--QQTIAAINKFQDDPALLDTILPRCVPLLTKSFFCMSQRD--QKLVAELFYNLDKISHSKVLKSLDTSIFRLNEILNYLQDRASPSSFSDVLCVYLNLSWLSVILLSPYAFK-----------------------DKFNKTLQVSSRFENYPICIPPINKIKAVLYFKNFT----------DAFDQLPEREQAN-----------VPFLNQFLKLFIQSSEKANYYFSNENLRHLQQVALSNDGIKLLPKLFQISFNHGSHDILDAIVEFFHDHLSSNSTDTRFQLAHSFAKIAKFLHQADPAS------FIELIDYTIENTVSLLQAPCDSIDS-----------------------------------NELHTSLLIIAEVALAKILPIDLVDRVLTLIIPKTCHFQKSHFQIIKGHHIRDSTNFIIWSVIRSNRSNSLSPQVLQSLLSHLLINAFFDPELIIRYSSFAALQELLGRSNKSLALNQNDIALILQANWKDLPRSFEENSGLIRRLFNPENTSKSAVCVWKVFRDWSFNWNLLENLHLTTMKLNIDYNLVPLIKSKLSSPALLQEVLNKAGSSVTQNCQILYLYLKLFENDVNCPKISEICIDIYQKKIKFQLTTQAKRQFNDNSPELFQ---------IFVILKYWQLTGQNDFNQELFWKFVDIVSPQK-----------------------------------------KLNLYNEFIPIIQQIISQCVSLNYTRIVQLIKSDNELTCRSICHMPDQEKMCSLFFSQFPLLS-------------PQSRSLLIGELDHHWDVR--------ISLLPSNSYRKFRNIIINCLDDYTITQQGDVGRLVRIQALKLMQSHPDFLS---------GDCDSINPKLTRLLAEPVPEIR----KLSYQLLASATSQITVLSD-SSILNFRHKQGLSEEFWKG----YAVSAGAIHFTDSQLTSSIDSFIVYYRSLSPSQQLELCHDLIRIIPSAKQIAESRIRDRNKDPLTGGMRFDTIKFTIHCVKFWTRIMESG---LVVLHPNFNFQGVFAKFYNLHLLDCTTLRVSVIKFFPFLAISCYHTMRENADQKNLSNIILKRLLVLVKREYAATKSKFMTDQNVALQG---MFQIFLELGVTRQLQALQVAC-QKHELANILESDITL----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: : .: :: :.::*::* ***. * : * . . : . : :* : *: *.: : . . : : : .*.... *: * *:*: * *: :. : :: . : * . *.* : : :* . * . :: :...: :: *: : :.. * .:: . *.. : :: : . .* :.:: * . . : :: .**: : *: : : * . * :**:. :* : ::.::: : : : ::**:: :: *:. *: ..:.:.* .: : * *: *.** :: * :: **:** :** . .:. . : : ..: * * : :. . : *: .*. . * * .: . : . * : :: : * : * : . : : . :: :.. .:: :: .*: : . : ::. : ::. .: .: : : : : : : : .::* : : : .. . :. :. :: .:.:** .:**:* ** ::. : . . . : . : * : . * : *: . *. : . .: .: . * :. : :. :. : . *: * *:. : . .: .: . :.: :. :: * . . * : : : .: . : : : : . :* :: : * : . . ::. : ::. *. * * . ::.*.::: . ", "identical_positions": 86, "similar_positions": 312, "identity": "6.86%" }, { "cls_id": "homologset.agr.SGD:S000005883", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q921G7-1", "uniprot_id": "ETFD_MOUSE", "id": "Q921G7-1", "name": "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "aln": "MLVRLTKLSCPAYHWFHALKIKK-CLPLCAPRCSSTSAVPQITTHYTVHPREKDKRWEGVNMERFAEEADVVIVGAGPAGLSAAIRLKQLAAEQGK-DIRVCLVEKAAQIGAHTLSGACLDPAAFKELFPDWK-EKGAPLN----TPVTEDRFAILTEKHRIPVPILPGLPMNNHG-NYIVRLGHLVSWMGEQAEALGVEVYPGYAAAEVLYHEDGSVKGIATNDVGIQKDGAPKTTFERGLELHAKVTVFAEGCHGHLAKQLYKKFDLRASCDAQTYGIGLKELWIIDEKKWKPGRVDHTVGWPLDRHTYGGSFLYHLNEGEPLVAVGFVVGLDYQNPYLSPFREFQRWKHHPSIQPTLEGGKRIAYGARALNEGGLQSIP-KLTFPGGLLIGCSPGFMNVPKIKGTHTAMKSGSLAAESIFKQLTSENLQSKTTG-------------LHVTEYEDNLKQSWVWKELHAVRNIRPSCHGILGVYGGMIYTGIFYWILRGMEPWTLKHKG-SDSDQLKPAKDCTPIEYPKPDGQISFDLLSSVALSGTNHEHDQPAHLTLKDDSIP--VNRNLSIYDGPEQRFCPAGVYEFVPLEQG-DGFRLQINAQNCVHCKTCDIKDPSQNINWVVPEGGGGPAYNGM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UPE1-1", "uniprot_id": "ETFD_RAT", "id": "Q6UPE1-1", "name": "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "aln": "MLVRLTKLSCPAYQWFHALKIKK-CLPLCAPRCSSTSAVPQITTHYTIHPREKDKRWEGVNMERFAEEADVVIVGAGPAGLSAAIRLKQLAAEQEK-DIRVCLVEKAAQIGAHTLSGACLDPAAFKELFPDWK-EKGAPLN----TPVTEDRFAILTEKHRIPVPILPGLPMNNHG-NYIVRLGHLVSWMGEQAEALGVEVYPGYAAAEVLYHEDGSVKGIATNDVGIQKDGAPKTTFERGLELHAKVTIFAEGCHGHLAKQLYKKFDLRASCDAQTYGIGLKELWVIDEKKWKPGRVDHTVGWPLDRHTYGGSFLYHLNEGEPLVAVGFVVGLDYQNPYLSPFREFQRWKHHPSIRPTLEGGKRIAYGARALNEGGLQSIP-KLTFPGGLLIGCSPGFMNVPKIKGTHTAMKSGSLAAEAIFKQLTSENLQSKTAG-------------LHVTEYEDNLKQSWVWKELHAVRNIRPSCHGILGVYGGMIYTGIFYWILRGMEPWTLKHKG-SDSEQLKPAKDCTPIEYPKPDGQISFDLLSSVALSGTNHEHDQPAHLTLKDDSIP--VNRNLSIYDGPEQRFCPAGVYEFVPLEQG-DGFRLQINAQNCVHCKTCDIKDPSQNINWVVPEGGGGPAYNGM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16134-1", "uniprot_id": "ETFD_HUMAN", "id": "Q16134-1", "name": "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "aln": "MLVPLAKLSCLAYQCFHALKIKKNYLPLCATRWSSTSTVPRITTHYTIYPRDKDKRWEGVNMERFAEEADVVIVGAGPAGLSAAVRLKQLAVAHEK-DIRVCLVEKAAQIGAHTLSGACLDPGAFKELFPDWK-EKGAPLN----TPVTEDRFGILTEKYRIPVPILPGLPMNNHG-NYIVRLGHLVSWMGEQAEALGVEVYPGYAAAEVLFHDDGSVKGIATNDVGIQKDGAPKATFERGLELHAKVTIFAEGCHGHLAKQLYKKFDLRANCEPQTYGIGLKELWVIDEKNWKPGRVDHTVGWPLDRHTYGGSFLYHLNEGEPLVALGLVVGLDYQNPYLSPFREFQRWKHHPSIRPTLEGGKRIAYGARALNEGGFQSIP-KLTFPGGLLIGCSPGFMNVPKIKGTHTAMKSGILAAESIFNQLTSENLQSKTIG-------------LHVTEYEDNLKNSWVWKELYSVRNIRPSCHGVLGVYGGMIYTGIFYWILRGMEPWTLKHKG-SDFERLKPAKDCTPIEYPKPDGQISFDLLSSVALSGTNHEHDQPAHLTLRDDSIP--VNRNLSIYDGPEQRFCPAGVYEFVPVEQG-DGFRLQINAQNCVHCKTCDIKDPSQNINWVVPEGGGGPAYNGM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7JWF1-1", "uniprot_id": "ETFD_DROME", "id": "Q7JWF1-1", "name": "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "aln": "-MSALMKMHR----------VRRLFSPALARSISDVAKYPRITTHYTLNPREKDERWTEVDMERCVEEVDLVIVGGGPAGMSAAIRAKQLAAEKDQ-EIRVCVVEKAAEVGGHILSGAVIDPISLNELIPDWQ-EQGAPLN----TPVTKDTFSFLTGSGRISIPVFKGWPMDNHG-NYVVRLGHLVKWLGDQAEALGVEIYPGCAASEVLFHEDGSVKGIATNDVGIAKSGAPKDTFARGMELHAKTTIFAEGCRGHLTKQIMQKFGLNEGSEPQAYGIGLKEVWEIAPEKHQPGLVEHTIGWPLDRFTYGGSFLYHLNEPTPTIAVGFVVGLNYKNPWLSPFQEFQRFKTHPKVRDVFEGATRIAYGARAINEGGFQSLPQKLSFPGGCLVGCSAGFLNVPRIKGSHYAMKSGMLAAESAFEAINAD--AQSTAG-------------VEPTGYAEKIKDSFVWKDLYSVRNVHPSFHNPLGLYGGLVLSG-FSIFMGGREPWTLKHGP-QDHESLKPASSCPPIVYPKPDGKISFDLLSSVALTGTNHEGDQPAHLTLKDDRIP--VDHNLALYEGPEQRFCPAGVYEYVPNEEG-GNMKLQINAQNCIHCKTCDIKDPKQNINWVVPEGGGGPAYNGM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08822-1", "uniprot_id": "ETFD_YEAST", "id": "Q08822-1", "name": "Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "aln": "-MIKFTNENLIR-----GIRMTISAKSRHLALGTDMTRKFSLSCRFLNKANLTEEEKELLNEPRARDYVDVCIVGGGPAGLATAIKLKQLDNSSGTGQLRVVVLEKSSVLGGQTVSGAILEPGVWKELFPDEKSDIGIPLPKELATLVTKEHLKFLKGKWAISVPEPS--QMINKGRNYIVSLNQVVGYLGEKAEEVGVEVYPGIAVSDLIYDENNAVKGVITKDAGISKSGKPKETFERGMEFWARQTVLAEGCHGSLTKQALAKYDLRKGRQHQTYGLGIKEVWEVKPENFNKGFAAHTMGYPLTNDVYGGGFQYHFGDG--LVTVGLVVGLDYKNPYVSPYKEFQKMKHHPYYSKVLEGGKCIAYAARALNEGGLQSVP-KLNFPGGVLVGASAGFMNVPKIKGTHTAMKSGLLAAESIFESIKGLPVLEEVEDEDAKMAMFDKEATINLESYESAFKESSIYKELYEVRNIRPSFSGKLGGYGGMIYSGIDSLILKGKVPWTLKFDEKNDGEILEPASKYKPIEYPKPDGVISFDILTSVSRTGTYHDDDEPCHLRVPGQDMVKYAERSFPVWKGVESRFCPAGVYEFVKDEKSPVGTRLQINSQNCIHCKTCDIKAPRQDITWKVPEGGDGPKYTLT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . :. : :: :: .. .::. :: * : .*: ***.****:::*:: *** ::** ::**:: :*.: :*** ::* :**:** : : * ** * **:: : :*. . *.:* * *:* **:* *.::* ::*::** :***:*** *.:::::.::.:***: *:*.** *.* ** ** **:*: *: *::****:* *:** *:.*. . : *:**:*:**:* : :: : * . **:*:** . .***.* **:.: :::*:****:*:**::**::***: * ** .:**.. ***.***:****:**:* **.**** *:*.*.**:***:***:* ***** ****: *: :.. ... . :. * . :*:* ::*:*: ***::** . ** ***:: :* :: * *****. .* : *:**.. ** ****** ****:*:**: :** *: *:*.** : .: : .::.:.::.* *.*********:* *:. . :****:***:******** * *:*.* *****.** *. ", "identical_positions": 247, "similar_positions": 198, "identity": "38.47%" }, { "cls_id": "homologset.agr.SGD:S000005884", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70492-1", "uniprot_id": "SNX3_MOUSE", "id": "O70492-1", "name": "Sorting nexin-3", "aln": "---------------------------------------------MAET-VADTRRLITK---PQNLNDAYGPPSNFLEIDVSNPQ-TVGVGR---GRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSELERES------KVVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQN-ERCLHMFLQDEIIDKSYTPSKIRHA---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60493-1", "uniprot_id": "SNX3_HUMAN", "id": "O60493-1", "name": "Sorting nexin-3", "aln": "---------------------------------------------MAET-VADTRRLITK---PQNLNDAYGPPSNFLEIDVSNPQ-TVGVGR---GRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSELERES------KVVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQN-ERCLHMFLQDEIIDKSYTPSKIRHA---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5U211-1", "uniprot_id": "SNX3_RAT", "id": "Q5U211-1", "name": "Sorting nexin-3", "aln": "---------------------------------------------MAET-VADTRRLITK---PQNLNDAYGPPSNFLEIDVSNPQ-TVGVGR---GRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSELERES------KVVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQN-ERCLHMFLQDEIIDKSYTPSKIRHA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70493-1", "uniprot_id": "SNX12_MOUSE", "id": "O70493-1", "name": "Sorting nexin-12", "aln": "---------------------------------------------MSDTAVADTRRLNSK---PQDLTDAYGPPSNFLEIDIFNPQ-TVGVGR---ARFTTYEVRMRTNLPIFKLKESCVRRRYSDFEWLKNELERDS------KIVVPPLPGKALKRH-PFRGDEGIFEESFIEERRQGLEQFINKIAGHPLAQN-ERCLHMFLQEEAIDRNYVAGKVLGEKDC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A719-1", "uniprot_id": "D4A719_RAT", "id": "D4A719-1", "name": "", "aln": "MRARVRVVAGCGLAGYFASGRGRARSCLRPLSPTPFAGTGLFFGKMSDTAVADTRRLNSK---PQDLTDAYGPPSNFLEIDIFNPQ-TVGVGR---ARFTTYEVRMRTNLPIFKLKESCVRRRYSDFEWLKNELERDS------KIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRQGLEQFINKIAGHPLAQN-ERCLHMFLQEEAIDRNYVPGKVLGEKDC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UMY4-2", "uniprot_id": "SNX12_HUMAN", "id": "Q9UMY4-2", "name": "Sorting nexin-12", "aln": "---------------------------------------------MSDTAVADTRRLNSK---PQDLTDAYGPPSNFLEIDIFNPQ-TVGVGR---ARFTTYEVRMRTNLPIFKLKESCVRRRYSDFEWLKNELERDS------KIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRQGLEQFINKIAGHPLAQN-ERCLHMFLQEEAIDRNYVPGKVRQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VG51-1", "uniprot_id": "Q9VG51_DROME", "id": "Q9VG51-1", "name": "Sorting nexin-3", "aln": "------------------------------------------MMVESDGTADATRRLNVK---KQTLDDAYAVPANFLEIDVVNPLTTMAAGK---KRYTDYEVRMRTNLPVFKVKESSVRRRYSDFEWLRNELERDS------KIVVPPLPGKAWKRQMPFRGDEGIFDESFIEERRKGLEAFINKIAGHPLAQN-ERCLHMFLQENVIDKNYVPGKIRNT---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08826-1", "uniprot_id": "SNX3_YEAST", "id": "Q08826-1", "name": "Sorting nexin-3", "aln": "------------------------------------------MPREFKSFGSTEKSLLSKGHGEPSYSEIYAEPENFLEIEVHNPKTHIPNGMDSKGMFTDYEIICRTNLPSFHKRVSKVRRRYSDFEFFRKCLIKEISMLNHPKVMVPHLPGKILLSN--------RFSNEVIEERRQGLNTWMQSVAGHPLLQSGSKVLVRFIEAEKFVG-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * * : *. * *****:: ** : * :* **: :**** *: : * *********:::. * :: *::** **** : *.:..****::**: :::.:***** *. .: * *:: : : ", "identical_positions": 53, "similar_positions": 40, "identity": "23.56%" }, { "cls_id": "homologset.agr.SGD:S000005885", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62725-1", "uniprot_id": "NFYC_RAT", "id": "Q62725-1", "name": "Nuclear transcription factor Y subunit gamma", "aln": "----------------------------------------------------------------------------------------------------------------MSTEGGFGSTSSSDAQQSLQSFWPRVMEEIRNLT------VKDFRVQELPLARIKKIMKLDEDVKMISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPRDELKPPKRQEEVRQSVTP------------------------------------------------------------AEPVQYYFTLAQQPTAVQVQGQQQGQQTTS-STTTIQPGQ----------IIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQ------------------------------------------------AQQAQSG-TGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQ-------------------ITQTEVQQGQQQFSQFTDGQ--------------------------------------------------------------------------------------------------------QLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQ-TPQVTGD--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13952-1", "uniprot_id": "NFYC_HUMAN", "id": "Q13952-1", "name": "Nuclear transcription factor Y subunit gamma", "aln": "----------------------------------------------------------------------------------------------------------------MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLT------VKDFRVQELPLARIKKIMKLDEDVKMISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPRDELKPPKRQEEVRQSVTP------------------------------------------------------------AEPVQYYFTLAQQPTAVQVQGQQQGQQTTS-STTTIQPGQ----------IIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQ------------------------------------------------AQQAQSG-TGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQGQRNASQGKPRRCLKETLQITQTEVQQGQQQFSQFTDGQRNSVQQARVSELTGEAEPREVKATGNSTPCTSSLPTTHPPSHRAGASCVCCSQPQQSSTSPPPSDALQWVVVEVSGTPNQLETHRELHAPLPGMTSLSPLHPSQQLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQ-APQVTGD--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70353-1", "uniprot_id": "NFYC_MOUSE", "id": "P70353-1", "name": "Nuclear transcription factor Y subunit gamma", "aln": "----------------------------------------------------------------------------------------------------------------MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLT------VKDFRVQELPLARIKKIMKLDEDVKMISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPRDELKPPKRQEEVRQSVTP------------------------------------------------------------AEPVQYYFTLAQQPTAVQVQGQQQGQQTTS-STTTIQPGQ----------IIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQ------------------------------------------------AQQTQSG-TGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQ-------------------ITQTEVQQGQQQFSQFTDGQ--------------------------------------------------------------------------------------------------------QLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQ-TPQVTGD--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3B3Q2-1", "uniprot_id": "A0A8M3B3Q2_DANRE", "id": "A0A8M3B3Q2-1", "name": "Nuclear transcription factor Y subunit gamma", "aln": "----------------------------------------------------------------------------------------------------------------MSADS-FG-AGGSDAQQSLQSFWPRVMEEIRNLT------VKDFRVQELPLARIKKIMKLDEDVKMISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPRDDLKPPKRQEEVRQSVAP------------------------------------------------------------TEPVQYYFTLAQQPSAVQVQGQQQGQQVSAPTATTLQPGQ----------IIIAQPQQGQSAPVTMQVGEGQQVQIVQAAAQGQ------------------------------------------------AQAQTAQPAGQTMQVMQQIITNTGEIQQIPVQLNTGQLQYIRLAQPVSGTQVVQGQIQTLAANTQQ-------------------LSQTEVQQGQQQFNQFTDGQ--------------------------------------------------------------------------------------------------------QLYQIQQVTMPAGQELTQPMFIQSTNQTADGQVTTQVSAD--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3V9-1", "uniprot_id": "Q9W3V9_DROME", "id": "Q9W3V9-1", "name": "Nuclear transcription factor Y subunit gamma", "aln": "-MYATNNGGTNKAPNSNATSMFDNTITVTPIKMELGQAYAKSQNSAAMQRRTPNAVVVTSSSTVSSAQQQQQQQGQQQQQTVPMASLVSNACTLVNPSMSVTVATTVASGAKEKTTKATRTQVARKPPPTIDNFWPNIVSEVHSIG------QVDAKHQVLPLARIKKIMKLDENAKMIAGEAPLLFAKACEYFIQELTMHAWVHTEESRRRTLQRSDIAQAIANYDQFDFLIDIVPREEIKPSSAQKTKDGSTSSSSGMAGAASSAASTSNTATSNAAASVAGNATATGNFVASGSTVPATTAGGLKLDTTGATNAAEVLGFSTVNSDIFSAQLQQQQQQQQQHAAQQQQQQQQQQHHQAHPQQVQIIQQGAGGQQLQYFIALPSQQAAQLVQQPQPAQNHLPINILSTQQPTQQLILTAGPNGQLTATPAPQTTAQQQTALLQNLAQQQQQHQQHQQQIQLLQQVVTPTGELTNVPIAINASHLNLLQRLQMQQQQQQQQQQQQQQQQQQQVIIPTQLLTTQQLLQLGGAPTVAHQQQQQQQQHANLTQQS-------------------------------------------------------------------------------------------------NASAVASGTPIFINSTMTGAQAAATQAQQQQSAQQQQAQTISTMSTDRTLTGGFR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02516-1", "uniprot_id": "HAP5_YEAST", "id": "Q02516-1", "name": "Transcriptional activator HAP5", "aln": "MTDRNFSPQQGQGPQESLPEGPQPSTMIQREEMNMPRQYSEQQQLQENEGEGENTRLPVSEEEFRMVQELQAIQAGHDQANLPPSGRGSLEGEDNGNSDGADGEMDEDD-EEYDVFRNVGQGLVGHYKEIMIRYWQELINEIESTNEPGSEHQDDFKSHSLPFARIRKVMKTDEDVKMISAEAPIIFAKACEIFITELTMRAWCVAERNKRRTLQKADIAEALQKSDMFDFLIDVVPRRPLPQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . : :* .::.*:.. * : : **:***:*:** **:.***:.***::****.: ** ***::** :* .:*****: *** *: : * ******:*** : ", "identical_positions": 50, "similar_positions": 35, "identity": "7.09%" }, { "cls_id": "homologset.agr.SGD:S000005886", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DF21-1", "uniprot_id": "SMAG1_RAT", "id": "B5DF21-1", "name": "Protein Smaug homolog 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLLPKILAHSIDHNQHIEESRQLLSYALIHPATSLEDRSALAMWLNHLEDRTSTSFGSQN---------------------------------RGRSDSVDYGQTHYYHQRQNSEDKLNGWQNSRDSGICISASNWQDKSLGCENGHVPLYSSSSVPATINTIGTSTSTI----------------------------------------------------------------------LSGQAHHSPLKRSVSLTPPMNVPNQPLGH--------------GWMSHEDLRARGPQCLPSDHAPLSPQSSVASSGSGGSEHLEDQTTARN---------------------------------TFQEEGSGMKDVPAWLKSLRLHKYAALFSQMTYEEMMALTECQLEAQNVTKGARHKIVISIQKLKERQNLLKSLERDIIEG-GSLRIPLQELHQMILTPIKAYSSPST-------TPEVR---RREP------LLM--ESPSPDCKDSAATVTSATASASAGASGGLQPPQLSSCDGELAVAPLPEGDLPGQFTRVMGKVCTQLLVSRPDEENISSYLQLLDKCLVHEAFTETQKKRLLS---WKQQVQKLFRSFPRKTLLDISGYRQQRNRGFGQ-SNSLPTASSVGSGMGRRNPRQYQIASRNVPSARLGLLGTSGFVSSNQRHTAANPTIMKQGRQNLWFANPGGSNSVPSRTHSSVQKTRSLPVHTSPQNMLMFQQPEFQLPVTEPDINNRLESLCLSMTEHALGDGVDRTSTI-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CBY1-1", "uniprot_id": "SMAG1_MOUSE", "id": "Q8CBY1-1", "name": "Protein Smaug homolog 1", "aln": "-----------------------------------------------------------------------MMFRDQVGVLAGWFKGWNECEQTVALLSLLKRVSQTQARFLQLCLEHSLAD------------------------------------CAELHVLEGEAN----------------SPGIINQWQQESKDKVISLLLTHLPLLKPGNLDAKAEYMKLLPKILAHSIEHNQHIEESRQLLSYALIHPATSLEDRSALAMWLNHLEDRTSTSFGSQN---------------------------------RGRSDSVDYGQTHYYHQRQNSDDKLNGWQNSRDSGICISASNWQDKSLGCENGHVPLYSSSSVPATINTIGTGASTI----------------------------------------------------------------------LSGQAHHSPLKRSVSLTPPMNVPNQPLGH--------------GWMSHEDLRARGPQCLPSDHAPLSPQSSVASSGSGGSEHLEDQTTARN---------------------------------TFQEEGSGMKDVPAWLKSLRLHKYAALFSQMTYEEMMALTECQLEAQNVTKGARHKIVISIQKLKERQNLLKSLERDIIEG-GSLRTPLQELHQMILTPIKAYSSPST-------TPEVR---CREP------SLM--ESPSPDCKDSAAAVTSATASASAGASGGLQPPQLSSCDGELAVAPLPEGDLPGQFTRVMGKVCTQLLVSRPDEENISSYLQLLDKCLVHEAFTETQKKRLLS---WKQQVQKLFRSFPRKTLLDISGYRQQRNRGFGQ-SNSLPTASSVGSGMGRRNPRQYQIASRNVPSARLGLLGTSGFVSSNQRHTAANPTIMKQGRQNLWFANPGGSNSMPSRTHSSVQKTRSLPVHTSPQNMLMFQQPEFQLPVTEPDINNRLESLCLSMTEHALGDGVDRTSTI-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPU9-1", "uniprot_id": "SMAG1_HUMAN", "id": "Q9UPU9-1", "name": "Protein Smaug homolog 1", "aln": "-----------------------------------------------------------------------MMFRDQVGVLAGWFKGWNECEQTVALLSLLKRVSQTQARFLQLCLEHSLAD------------------------------------CAELHVLEREAN----------------SPGIINQWQQESKDKVISLLLTHLPLLKPGNLDAKVEYMKLLPKILAHSIEHNQHIEESRQLLSYALIHPATSLEDRSALAMWLNHLEDRTSTSFGGQN---------------------------------RGRSDSVDYGQTHYYHQRQNSDDKLNGWQNSRDSGICINASNWQDKSMGCENGHVPLYSSSSVPTTINTIGTSTSTI----------------------------------------------------------------------LSGQAHHSPLKRSVSLTPPMNVPNQPLGH--------------GWMSHEDLRARGPQCLPSDHAPLSPQSSVASSGSGGSEHLEDQTTARN---------------------------------TFQEEGSGMKDVPAWLKSLRLHKYAALFSQMTYEEMMALTECQLEAQNVTKGARHKIVISIQKLKERQNLLKSLERDIIEG-GSLRIPLQELHQMILTPIKAYSSPST-------TPEAR---RREPQAPRQPSLMGPESQSPDCKDGAAATG-ATATPSAGASGGLQPHQLSSCDGELAVAPLPEGDLPGQFTRVMGKVCTQLLVSRPDEENISSYLQLIDKCLIHEAFTETQKKRLLS---WKQQVQKLFRSFPRKTLLDISGYRQQRNRGFGQ-SNSLPTAGSVGGGMGRRNPRQYQIPSRNVPSARLGLLGTSGFVSSNQRNTTATPTIMKQGRQNLWFANPGGSNSMPSRTHSSVQRTRSLPVHTSPQNMLMFQQPEFQLPVTEPDINNRLESLCLSMTEHALGDGVDRTSTI-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80XS6-1", "uniprot_id": "SMAG2_MOUSE", "id": "Q80XS6-1", "name": "Protein Smaug homolog 2", "aln": "-----------------------------------------------------------------------MMFRDQVGILASWFKGWNECEQTVALLSLLKRVTRTQARFLQLCLEHSLAD------------------------------------CNDIHLLESEAN----------------SAAIVSQWQQESKEKVVSLLLSHLPLLQPGNTEAKSEYMRLLQKVLAYSIESNAFIEESRQLLSYALIHPATTLEDRNALALWLSHLEERLASGFRTR--------------------------------------------PEPSYHSRQGSDE----WGGPAELAPGEAGPGWQDKPP-RENGHVPFHPSSSVPPAINSIGSNANTG----------------------------------------------------------------------LPCQIHPSPLKRSMSLIPTS--PQAPG----------------EWPSPEELGARAAFTTP-DHAPLSPQSSVASSGS---EQTEEQGSSRN---------------------------------TFQEDGSGMKDVPSWLKSLRLHKYAALFSQMSYEEMMTLTEQHLESQNVTKGARHKIALSIQKLRERQSVLKSLEKDVLEG-GNLWNALQELQQIIITPIKAYSVLQA-------TPTAKDEGRGEP------LLP---GAEPPLTHPGSDKGTEAKDPPAAENYPPPPAPAPSDSSEPAPAPVADGDIPSQFTRVMGKVCTQLLVSRPDEENITSYLQLIEKCLTHEAFTETQKKRLLS---WKQQVLKLLRTFPRKAALDMQSYRQQKGWAFG--SNSLPIAGSVGMGVARRTQRQFPMPPRALPPGRMGLLSPSGIGGVSPRHALTSPSLGGQGRQNLWFANPGGSNSMPSQSRSSVQRTHSLPVHSSPQAILMFP-PDCPVPGPDLEINPTLESLCLSMTEHALGDGTDKTSTI-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1W2Q6J6-1", "uniprot_id": "A0A1W2Q6J6_RAT", "id": "A0A1W2Q6J6-1", "name": "", "aln": "-----------------------------------------------------------------------MMFRDQVGILASWFKGWNECEQTVALLSLLKRVTRTQARFLQLCLEHSLAD------------------------------------CNDIHLLESEAN----------------SAAIVSQWQQESKEKVVSLLLSHLPLLQPGNTEAKSEYMRLLQKVLAYSIESNAFIEESRQLLSYALIHPATTLEDRNALALWLSHLEERLASGFRTR--------------------------------------------PEPSYHSRQGSDE----WGGPAELAPGEAGSGWQDKPP-RENGHVPFHPSSSVPPAINSIGSNANTG----------------------------------------------------------------------LPCQIHPSPLKRSMSLIPTS--PQAPG----------------EWPSPEELGARAAFTTP-DHAPLSPQSSVASSGS---EQTEEQGSSRN---------------------------------TFQEDGSGMKDVPSWLKSLRLHKYAALFSQMSYEEMMTLTEQHLESQNVTKGARHKIALSIQKLRERQSVLKSLEKDVLEG-GNLRNALQELQQIIITPIKAYSVLQA-------TPTAKDGGRGEP------LLP---GAEPPLTHPGSDKGTEAKDPPAAENYPPPPAPAPSDSSEPAPAPVADGDIPSQFTRVMGKVCTQLLVSRPDEENITSYLQLIEKCLTHEAFTETQKKRLLS---WKQQVLKLLRTFPRKAALDMQSYRQQKGWAFG--SNSLPIAGSVGMGVARRTQRQFPMPPRALPPGRMGLLSPSGIGGVSPRHALTSPSLGGQGRQNLWFANPGGSNSMPSQSRSSVQRTHSLPVHSSPQAILMFP-PDCPVPGPDLEINPTLESLCLSMTEHALGDFDESCCPEPDSEH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5PRF9-1", "uniprot_id": "SMAG2_HUMAN", "id": "Q5PRF9-1", "name": "Protein Smaug homolog 2", "aln": "-----------------------------------------------------------------------MMFRDQVGILAGWFKGWNECEQTVALLSLLKRVTRTQARFLQLCLEHSLAD------------------------------------CNDIHLLESEAN----------------SAAIVSQWQQESKEKVVSLLLSHLPLLQPGNTEAKSEYMRLLQKVLAYSIESNAFIEESRQLLSYALIHPATTLEDRNALALWLSHLEERLASGFRSR--------------------------------------------PEPSYHSRQGSDE----WGGPAELGPGEAGPGWQDKPP-RENGHVPFHPSSSVPPAINSIGSNANTG----------------------------------------------------------------------LPCQIHPSPLKRSMSLIPTS--PQVPG----------------EWPSPEELGARAAFTTP-DHAPLSPQSSVASSGS---EQTEEQGSSRN---------------------------------TFQEDGSGMKDVPSWLKSLRLHKYAALFSQMSYEEMMTLTEQHLESQNVTKGARHKIALSIQKLRERQSVLKSLEKDVLEG-GNLRNALQELQQIIITPIKAYSVLQATVAAATTTPTAKDGAPGEP------PLP---GAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPAPAPVADGDIPSQFTRVMGKVCTQLLVSRPDEENITSYLQLIEKCLTHEAFTETQKKRLLS---WKQQVLKLLRTFPRKAALEMQNYRQQKGWAFG--SNSLPIAGSVGMGVARRTQRQFPMPPRALPPGRMGLLSPSGIGGVSPRHALTSPSLGGQGRQNLWFANPGGSNSMPSQSRSSVQRTHSLPVHSSPQAILMFP-PDCPVPGPDLEINPTLESLCLSMTEHALGDGTDKTSTI-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q23972-1", "uniprot_id": "SMG_DROME", "id": "Q23972-1", "name": "Protein Smaug", "aln": "MKYATGTDNAMTSGISGQTNNSNSASNEMQPTTSTPTAAHKEATSTATTTATYANGNPNSNANPSQSQPSNALFCEQVTTVTNLFEKWNDCERTVVMYALLKRLRYPSLKFLQYSIDSNLTQNLGTSQTNLSSVVIDINANNPVYLQNLLNAYKTFQPCDLLDAMSSSSSDKDSMPCYGSDFQITTSAQCDERKLYARKEDILHEVLNMLPLLKPGNEEAKLIYLTLIPVAVKDTMQQIVPTELVQQIFSYLLIHPAITSEDRRSLNIWLRHLEDHIQAAAAGLTNRSYFLQPSPQLVAGGSSTGSGSCSSSATSSSTASCSSVASSSLCPASGSRSSRTNDWQTIAPPSKQLQNKLAGDWRGNGGGSSSGSINPLCDNLNGITLNELASSQNSLGLSLEGSSSLVNGVVAGAGSMLGIAGGDDHDTSFSKNGTEILDFDPVTADMGEACSLASSSLCGRNGGNPVEDRSQPPPNLQQQLLQPPPYASILMGNVGDQFGEINRWSLDSKIAALKTRRSNSLTTQTISSCSSSSNSSVITVNDNCSNSTENLAQFANKPRSFSLSIEHQRGALMNSGSDTRLDEFKPNYIKFHTRNVGMSGIGLWLKSLRLHKYIELFKNMTYEEMLLITEDFLQSVGVTKGASHKLALCIDKLKERANILNRVEQELLSGQMELSTAVEELTNIVLTPMKPLESPGP--------PEENIGLRFLK-------VIDIVTNTLQQDPYAVQDDETLGVLMWILDRSIHNEAFMNHASQLKDLKFKLSKMKISMVPKMHHVKPAGVGPNNGNINKPRWNGKTRKCDTKNGSNDRINNRKNSNDMLNFSLNCLPHPLPHHSQQAPPPLPQFDYNGYGGGPSHQPQYKSSSYPSFMGNPQQQPPPPPSSKSHHHPQQMQQMLQQHNHFPALPQQTPPQSHRRSLNNLILVAGGPQQPQQLIFKPGQGVLTNNGSNDNLVLERNQQSQQQQQQRKLSGGVSSAEQQPKKTMAAVVMENLAKFDQHFTLF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08831-1", "uniprot_id": "VTS1_YEAST", "id": "Q08831-1", "name": "RNA-binding protein VTS1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKHPYEEFPTGSKSP------------------------------------------------YNMSRGAHPGAVLLSPQSSAINKNNPGSNSGNNQGNSSVTANVLSPQSHSMSLNDMLDQQSFMLD---------------------------------------------------------------------TAGTRAQPLQQQQQQQQQQQQASLPSLN---------------IQTVSSTAAGSAIVSPMMQSPKALQSTLSSTSMYLD--------------------------------------------SFQRSPNNILGIPSQSGSIPLPQSRQSQQQSQSQKNDPNMGTNFSQDINQLCSWISMLNSSQQNTVMDNILSILNDDVLKY-TKLKIETLTNTPFISPPLPAIASPIP----------NRDDTQILN-------------IDSVFSSSPITNDPENTDNLLYQNWSPQPHSIPISQPIYDNITDASQRSKSAEPHVNSSPNLIPVQKQFNNGNSTKYKKLPSENPNYLSHSLSSSHSFFQ----PKKRSNMGNEYNSHHHHSLHHPLHNTTSYFSN--------TSRPSGTDLNKSNQNVFNNTITHPNAGPTSATSTSTSSNGNTPLSSNSSMNP--KSLTDPKLLKNIPMWLKSLRLHKYSDALSGTPWIELIYLDDETLEKKGVLALGARRKLLKAFGIVIDYKERDLIDRSAY--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :. :. . . . .: .. . ::* : . : * :. . : . : . . .. : :*:: : . .*: .: .: *: * : .: :: :. : .: . :: .:*. :: :::. .* :: .*: . . . . : . .: * . : : . . .: . . : . : : :. * . .* . . . . . : :.* . . : *. : : : : . . : . ", "identical_positions": 15, "similar_positions": 113, "identity": "1.48%" }, { "cls_id": "homologset.agr.SGD:S000005887", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70628-1", "uniprot_id": "PDE9A_MOUSE", "id": "O70628-1", "name": "High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGAGSSSYRPKAIYLDIDGRIQKVVFSKYCNSSD-------------------------IMDLFCIATGLPRNTTISLLTTDDAMVS------------------------------------------------------------------------------------IDPTMPAN------------------------------SERTPYKVRPVAVKQVS------------------------------------------------------------EREELIQGVLAQVAEQFSR-----AFKINELKAEVANH-----------LAVLEKRVELEGLKVVEIEK--------------------------------------------------------------------------------------------------------------------------CKSDIKKMREELAARNSR-TNCPCKYSFLDN-KKLTP------RRDVPTYPKYLLSPETIEALRKPTFDVWLWEP----NEMLSCLEHMYHDLGLVRDFSINPITLRRWLLCVHDNYRNNP--FHNFRHCFCVTQMMYSMVWLCGLQEK--FSQMDILVLMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAIAFQILAR-PECNIFASVPPEGFRQIRQGMITLILATDMARHAEIMDSFKEKMENFDYS---------------------NEEHLTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDRE--KSEGLPVA-PFMDRDKV-TKATAQIGFIKFVLIPMFETVTKLFP----------------------VVEETMLRPLWESREHYEELKQLDDAMKELQKK-TESLTSGAPENTTEKNRDAKDSEGHSPPN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8QZV1-1", "uniprot_id": "PDE9A_RAT", "id": "Q8QZV1-1", "name": "High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGAGSSSYRPKAIYLDIDGRIQKVVFSKYCNSSD-------------------------IMDLFCIATGLPRNTTISLLTTDDAMVS------------------------------------------------------------------------------------IDPTMPAN------------------------------SERTPYKVRPVAVKQVS------------------------------------------------------------EREELVQGVLAQVAEQFSR-----AFKINELKAEVANH-----------LAMLEKRVELEGLKVVEIEK--------------------------------------------------------------------------------------------------------------------------CKSDIKKMREELAARNNR-TNCPCKYSFLDN-KKLTP------RRDVPTYPKYLLSPETIEALRKPTFDVWLWEP----NEMLSCLEHMYHDLGLVRDFSINPITLRRWLLCVHDNYRSNP--FHNFRHCFCVTQMMYSMVWLCGLQEK--FSQMDILVLMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAIAFQILAR-PECNIFASVPPEGFRQIRQGMITLILATDMARHAEIMDSFKEKMENFDYS---------------------NEEHLTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDRE--KSEGLPVA-PFMDRDKV-TKATAQIGFIKFVLIPMFETVTKLFP----------------------IVEETMLRPLWESREHYEELKQLDDAMKELQKK-TENLTSGATENAPEKTRDAKDNEDRSPPN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O76083-1", "uniprot_id": "PDE9A_HUMAN", "id": "O76083-1", "name": "High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSD-------------------------IMDLFCIATGLPRNTTISLLTTDDAMVS------------------------------------------------------------------------------------IDPTMPAN------------------------------SERTPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSR-----AFKINELKAEVANH-----------LAVLEKRVELEGLKVVEIEK--------------------------------------------------------------------------------------------------------------------------CKSDIKKMREELAARSSR-TNCPCKYSFLDNHKKLTP------RRDVPTYPKYLLSPETIEALRKPTFDVWLWEP----NEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNP--FHNFRHCFCVAQMMYSMVWLCSLQEK--FSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAE-PECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYS---------------------NEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDRE--KSEGLPVA-PFMDRDKV-TKATAQIGFIKFVLIPMFETVTKLFP----------------------MVEEIMLQPLWESRDRYEELKRIDDAMKELQKK-TDSLTSGATEKSRERSRDVKNSEGDCA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B2M3-1", "uniprot_id": "A0A8M3B2M3_DANRE", "id": "A0A8M3B2M3-1", "name": "Phosphodiesterase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSASSAY--RMIYLEVDGRVQKVVFSRFCSPCD-------------------------IKELFCTATGVSRNTSISLLDSTGAMVS------------------------------------------------------------------------------------IDPTMPNN------------------------------TERSPYKVVPVTGSQLA------------------------------------------------------------DKEELFQNVLTQVAEQFSR-----AFKINELKTEVTNR-----------LAMLEKRVELEGMKVVEIEK--------------------------------------------------------------------------------------------------------------------------CRSDIKKLREEMASRNNS--------SFLEDNKKLTP------RRDVPSYPKYHLSQDTVEALKQPLFDVWQWES----NEMLSCLEHMYHDLGLVKDFNINPITLKRWLLCIHDNYRNNP--FHNFRHCFCVTQMMYSMIYLCGLQEK--FTQVDILILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQIFSQ-PDCNIFASFDPEAFKQIRQGTITLILATDMARHGEIMDSFKQKVDSFDYN---------------------NEEHVTCLKMVLIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDRE--KAEGLPVA-PFMDREKV-TKPTAQIGFIKFVLIPMFETVMKLFP----------------------QIEEVMVQPLRESRDKYEELKQIDDAMNEMQKKKTENLTTGGKKK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7UT66-1", "uniprot_id": "A0A8N7UT66_DANRE", "id": "A0A8N7UT66-1", "name": "Phosphodiesterase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSCIYFRRHLAGGTFEGWFWWICSWLR----------------------------------------VQVDLTVHFINMGSASSSYSPKTIYLDVDGKVQKVLFSRHCSPCD-------------------------IKELLCSSSNIPRNTAIMMTDPEGAIVS------------------------------------------------------------------------------------IDPTMPTN------------------------------NPNFLYKIIPLSASQLG------------------------------------------------------------EKEDMFQNVLSQVAEQFSR-----AFRINELKTEVTNR-----------LAMLEKRVELEGLKVVEIEK--------------------------------------------------------------------------------------------------------------------------CKNDMRKLRDEMTSRAGARVNCPCKYNFSDDGKKLTP------RRDIPSYPKYTLSQETIEALKKPTFDVWHWEH----NEMLSCLEYMYHDLGLVKEFNINPITLKRWLLGIQENYRSNP--FHNFRHCFCVSQMMYGMIHLCNLQEK--LTLTDLGILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILSL-PECNIFANVEPEAFKQIRQAIITLILATDMARHGEILDSFKHKVDHFDFT---------------------NEEHVACLKMVLIKCCDISNEVRPTEVAEPWVDCLLEEYFMQSDRE--KSEGLPVA-AFMDREKV-TKPTAQIGFIKFVLIPMFETVMKLFP----------------------QIEEIMVQPLRDSRDHYEELKQIDDAMTEAQKKKTESLSLGGKKK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7S6-1", "uniprot_id": "PDE9A_DROME", "id": "Q9I7S6-1", "name": "High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYQDSGCSSSSSRRGSSSAAAATSTAATAAETAAAAAATTTSSSDEETLETLTIITTTITDSDIHATTTTTTVIASGTATTAAAAATTATLATLATLASNSDIEDSSPVESEDSEECEYIEIDCQTTAQEGTSPSGGSSSSGNAVLLQRSSNNLQQQQQQQQQQQQHLQLQLQQADERLLRKIGYIASRVRCLSKYYGDFRLVNPYSARRQRRQLQEILLRHSIFDPGKEHQRAIVL----------------------------------------AAATAAIAGPLAAIDCVCGSSSISLEAVSSRSRSSELEDDHHEQDQVQEEQEQEQHQGDTEDNEEEQEHPSEKPERTDIEEEPPPAIAVTTTTTATVRRKSSSSSTISGTATVSG------------------------------------------------------------SVSVSASASQSFCSNNINLLEELLIQFYEEQDHRSNLTVIRHHHHQQHQQHQQQQRITNNNNNN--------------------------------------------NNCNSIQNNNNMSNPAATAAATATPSVEQPATSGTTNIHLQPTSLPDGSDNPRRRRASDCSAVQAALQNQLHCITLKNNNCGKAMPFHRGSCGAAGEHLLAANSIANRATIILSKSCSNVDGDATATAATALSSTVGGGIGGIGGSIKMRASATDIETNALNGARDAIVASNNGNNGNNGNNGNNEYSILQLNNTIIQCHFNDDDFRALVKDLKRKVEYTERMNWLCLSKRPLGPPHRKSSLPKHQEVKRRFLEICDTTFSEEVRAALRLPAFDSYEWSD----ADVIHLMQTMFVELGFIEKFSIPVDTLREWLYEVYKHYNEVP--FHNFRHCFCVAQMMYAITRQANLLSR--LGDLECLILLVSCICHDLDHPGYNNIYQINARTELALRYNDISPLENHHCSIAFRLLEH-PECNIFKNFSRDTFNNIREGIIRCILATDMARHNEILTQFMEITPIFDYS---------------------NRAHINLLCMILIKVADISNEARPMDVAEPWLDRLLQEFFAQSAAE--KSEGLPVT-PFMDPDKV-SKPGSQVRFIGLVLLPLFEALGELVP----------------------ELTELIIIPVRIALEYYRRLNDAQTKTRKSVADSNTSATSDSNSGTIDSNAAMVSTPGGASDKLSLDKGQGNSQGSGGGGGGGGGGGAGGGTGSGCGSNAAGSVSPQMPRSGSGISVKSRRSIPSQKSASRTSVDEPGGMASELHDLPEGSESGDSETATEVDVAEKTSKFKVDTEGSSNRSKSSHSTSRKSSREKRPSMIGELCSSGGGQRIRNSYGNIHGYHSNRCHFGNNRAVSLDQYSSAGNNRRLSDGLPQVISDSNVFYGRHNRSSTETTVAVGNPQDTNANTNHPVGCQLKELLARTEADSDGEGDGNGREDKKIPLVIPSMPQLATSSNGNISPTLVVTEQILPSNGSTRSSASSGRGGSGVPGGSGGSGMPGPSAGSGSSWKSRLRQFSDYFSFSFDKSNKRFGSTRSSPCPGSNSSSGRTNNNANGLGENQDGLGAGGGIKPGMCCTTITNSSGSTVKGETRGGTAGAGGGALTTMTTGNDAHQRHRAYSLDVPGMMRYSSNDSSRHPSNNTLQSAGGGAGLTTGLEVTAQRVPPSLSVEMGLASGSSSEAGPKI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M6Z8P7-1", "uniprot_id": "A0A8M6Z8P7_DANRE", "id": "A0A8M6Z8P7-1", "name": "Phosphodiesterase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATKIIYFTVNGRPEQAEFPIDCPAQD-------------------------VKDLFRAAAEAGPHDILKLYNTKGNIIN------------------------------------------------------------------------------------ISPQLASN------------------------------SPHSYYKLEVVAADCN-------------------------------------------------------SELLGSELAVALGFDLTSMEKRLQS------LEKRILTEAAETP---------AIVYEMKRQVESFREKLESV---------------EHLS---------------------------------------------------------------------------------------------------------WLGLFKDMSEGTHKPS----PFYHKRTL-----RKTREECEHVREKFLQMSSLEVSEEVRQYLKTPTFDNWQWED----AEIMVLLQVMYTDLDFISTFNIEPDVLQQFLYEVYRRYNNIP--FHNFKHCFCVTQMMYGLIWLTDLRSK--IDSIDLLIMLTSAVCHDLDHTGYNNAYQINARTELALRYNDISPLENHHCAVAFEILEK-TESNIFRNLPTEQYKRIREGIIKCILATDMSRHTDILNKFKAILPVFDFG---------------------NKDHRDVLMMIMIKVSDISNEARPMDVAEPWLDCLLQEFFNQSDME--KLEGLPVT-PFMDRDKV-TKPSSQTGFIRFVLFPLFIELANLFP----------------------CLEQHIIDPVRKALDYYTEMEKALEREKQNRALNETTVKTSTSK---EPDANLEAKPASL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3UEI1-1", "uniprot_id": "PDE4C_MOUSE", "id": "Q3UEI1-1", "name": "3',5'-cyclic-AMP phosphodiesterase 4C", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRRSGTALSFLWTERVREPV-DSGVAPVSPLGGGVILRRFSGTLLLPPLSSRLGSSGEAES-----------AAHVVFTIGTQGTQRN-------------------------------------------------------LGSAQSSFDLENG--LPGGKGLLDAQSGPSLGRALQPPVH--------------------HVQRRESFLYRSDSDHEPSPKAVSRTSS-AASD------------------------------------------------------------------------------LHGEDMIVTPFAQVLASLRTVRNNVAALAHGPG--------S-ATRQVLLGTPPHSSQQAAPT------------------------------------EDSGLQLVQETLEELDWCLEQLETLQTRRSVGEMASNKFKRMLN-RELSYLSETSRSGNQ-----------VSEYISQTFLDQQAEVELPQPPTED-------------------------------------------------------------------------------------------------------------------DPWPMAQITELRRSSHTS---------------------LPTAAIPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAVIFSVFQERDLLKTFQIPADTLLAYLLTLEGHYHSDV-AYHNSMHAADVVQSAHVLLGTPALEAV--FTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQG-ENCDIFRNLSTKQRLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVL-------------LLDNYSDRIQVLQSLVHCADLSNPAKPLPLYRQWTERIMAEFFQQGDRE--RESGLDIS-PMCDKHTA-SMEKSQVGFIDYIAQPLWETWADLV----------------------HPDAQELLDTLEDNREWYQSRIPCSP-----PHTMG-------------SDRFKFELTLEEAEEE----------------------------------------------------------------------------------------------------------------------------EEEEDEGQCTALNRESSELPST-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14644-1", "uniprot_id": "PDE4C_RAT", "id": "P14644-1", "name": "3',5'-cyclic-AMP phosphodiesterase 4C", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NSSRTSS-AASD------------------------------------------------------------------------------LHGEDMIVTPFAQVLASLRTVRSNVAALAHGAG--------S-ATRQALLGTPPQSSQQAAPA------------------------------------EESGLQLAQETLEELDWCLEQLETLQTRRSVGEMASNKFKRMLN-RELTHLSETSRSGNQ-----------VSEYISQTFLDQQAEVELPAPPTED-------------------------------------------------------------------------------------------------------------------HPWPMAQITGLRKSCHTS---------------------LPTAAIPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAVIFRVLQERDLLKTFQIPADTLLRYLLTLEGHYHSNV-AYHNSIHAADVVQSAHVLLGTPALEAV--FTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQG-ENCDIFQNLSTKQKLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVL-------------LLDNYSDRIQVLQSLVHCADLSNPAKPLPLYRQWTERIMAEFFQQGDRE--RESGLDIS-PMCDKHTA-SVEKSQVGFIDYIAHPLWETWADLV----------------------HPDAQELLDTLEDNREWYQSRVPCSP-----PHAIG-------------PDRFKFELTLEETEEE----------------------------------------------------------------------------------------------------------------------------EEEDERH----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08493-1", "uniprot_id": "PDE4C_HUMAN", "id": "Q08493-1", "name": "3',5'-cyclic-AMP phosphodiesterase 4C", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENLGVGEGAEACSRLSRSR-GRHSMTRAPKHLWRQPRR-PIRIQQRFYSDPDKSAGCRER-----------DLSPRPELRKSRLSWP-------------------------------------------------------VSSCRR-FDLENG--LSCGRRALDPQSSPGLGRIMQAPVP--------------------HSQRRESFLYRSDSDYELSPKAMSRNSS-VASD------------------------------------------------------------------------------LHGEDMIVTPFAQVLASLRTVRSNVAALARQQC--------LGAAKQGPVGNPS-SSNQLPPA------------------------------------EDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILN-RELTHLSETSRSGNQ-----------VSEYISRTFLDQQTEVELPKVTAEE-------------------------------------------------------------------------------------------------------------------APQPMSRISGLHGLCHSA--------------------SLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANV-AYHNSLHAADVAQSTHVLLATPALEAV--FTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQA-ENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVL-------------LLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRE--RESGLDIS-PMCDKHTA-SVEKSQVGFIDYIAHPLWETWADLV----------------------HPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDG-------------PDRFQFELTLEEAEEED---------------------------------------------------------------------------------------------------------------------------EEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O89084-1", "uniprot_id": "PDE4A_MOUSE", "id": "O89084-1", "name": "3',5'-cyclic-AMP phosphodiesterase 4A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRT-PIRIQQRGYSDSAERSEPERSPHRPIERADAVDTGDRPGLRTTRMSWPSSFHGTGTG-----------------------------------------------GGSSRRLEAENGPTPSPGRSPLDSQASPGL--MLHAGAA--------------------TSQRRESFLYRSDSDYDMSPKTMSRNSS-VASE------------------------------------------------------------------------------AHGEDLIVTPFAQVLASLRNVRSNFSLLTNVPI--------P-SNKRSPLGGPP-SVCKATLS------------------------------------EETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRMLN-RELTHLSEMSRSGNQ-----------VSEYISNTFLDKQHEVEIPSPTPRQRPFQ-------------------------------------------------------------------------------------------------------QPPPAAVQQAQPMSQITGLKKLVHTG--------------------SLN-INVPRFGVKTDQEDLLAQELENLSKWGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFHIPVDTMMTYMLTLEDHYHADV-AYHNSLHAADVLQSTHVLLATPALDAV--FTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQE-ENCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVL-------------LLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRE--RERGMEIS-PMCDKHTA-SVEKSQVGFIDYIVHPLWETWADLV----------------------HPDAQDILDTLEDNRDWYHSAIRQSPSPTLEEEPGVL--SDPAL-----PDKFQFELTLEEEDEE------------DSLEVPGLPCTEETL---LAPHDTRAQAMEQSKVKGQSPAVVEVAESLKQETASAHGAP---------EESAEAVGHS----FSLETSILPDLRTLSPSEEAQGLLGLPSMAAEVEAPRDHLAAMRACSACSGTSGDNSAVISAPGRWGSGGDPA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54748-1", "uniprot_id": "PDE4A_RAT", "id": "P54748-1", "name": "3',5'-cyclic-AMP phosphodiesterase 4A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRT-PIRIQQRGYPDSAERSETERSPHRPIERADAVDTGDRPGLRTTRMSWPSSFHGTGTG-----------------------------------------------GGSSRRLEAENGPTPSPGRSPLDSQASPGL--VLHAGAT--------------------TSQRRESFLYRSDSDYDMSPKAVSRSSS-VASE------------------------------------------------------------------------------AHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPI--------P-SNKRSPLGGPP-SVCKATLS------------------------------------EETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRMLN-RELTHLSEMSRSGNQ-----------VSEYISNTFLDKQNEVEIPSPTPRQRAFQ-------------------------------------------------------------------------------------------------------QPPPSVLRQSQPMSQITGLKKLVHTG--------------------SLN-TNVPRFGVKTDQEDLLAQELENLSKWGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFHIPVDTMMMYMLTLEDHYHADV-AYHNSLHAADVLQSTHVLLATPALDAV--FTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQE-ENCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVL-------------LLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRE--RERGMEIS-PMCDKHTA-SVEKSQVGFIDYIVHPLWETWADLV----------------------HPDAQDILDTLEDNRDWYHSAIRQSPSPPLEEEPGGL--GHPSL-----PDKFQFELTLEEEEEE------------DSLEVPGLPTTEETF---LAAEDARAQAVDWSKVKGPSTTVVEVAERLKQETASAYGAP---------QESMEAVGCS----FSPGTPILPDVRTLSSSEEAPGLLGLPSTAAEVEAPRDHLAATRACSACSGTSGDNSAIISAPGRWGSGGDPA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P27815-1", "uniprot_id": "PDE4A_HUMAN", "id": "P27815-1", "name": "3',5'-cyclic-AMP phosphodiesterase 4A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPPTVPSERSLSLSLPGPREGQATLKPPPQHLWRQPRT-PIRIQQRGYSDSAERAERERQPHRPIERADAMDTSDRPGLRTTRMSWPSSFHGTGTGS------------------------------------------GGAGGGSSRRFEAENGPTPSPGRSPLDSQASPGL--VLHAGAA--------------------TSQRRESFLYRSDSDYDMSPKTMSRNSS-VTSE------------------------------------------------------------------------------AHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPV--------P-SNKRSPLGGPT-PVCKATLS------------------------------------EETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRMLN-RELTHLSEMSRSGNQ-----------VSEYISTTFLDKQNEVEIPSPTMKEREKQQAP-----------------------------------------------------------------------------------------------RPRPSQPPPPPVPHLQPMSQITGLKKLMHSN--------------------SLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADV-AYHNSLHAADVLQSTHVLLATPALDAV--FTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQE-DNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVL-------------LLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRE--RERGMEIS-PMCDKHTA-SVEKSQVGFIDYIVHPLWETWADLV----------------------HPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESRGP--GHPPL-----PDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAELEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACAGTFGEDTSALPAPGGGGSGGDPT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B1AWC9-1", "uniprot_id": "B1AWC9_MOUSE", "id": "B1AWC9-1", "name": "Phosphodiesterase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKKSRSVMAVTADDNLKDYFECSLSKSYSSSSYTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDG------ISRPTTLPLTTLPSIAITTVSQE--------------------------------------------------------CFDVENG--PSPGRSPLDPQAGSSSGLVLHAAFPG-------------------HSQRRESFLYRSDSDYDLSPKAMSRNSS-LPSE------------------------------------------------------------------------------QHGDDLIVTPFAQVLASLRSVRNNFTLLTNLH----------GAPNKRSPAASQAPVSRVSLQ------------------------------------EESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN-RELTHLSEMSRSGNQ-----------VSEYISNTFLDKQNDVEIPSPTQKDREKKK-------------------------------------------------------------------------------------------------------------KQQ-LMTQISGVKKLMHSS--------------------SLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDV-AYHNSLHAADVAQSTHVLLSTPALDAV--FTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQE-EHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVL-------------LLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKE--RERGMEIS-PMCDKHTA-SVEKSQVGFIDYIVHPLWETWADLV----------------------QPDAQDILDTLEDNRNWYQSMIPQSPSPPLDERSRD---CQGLM------EKFQFELTLEEEDSE--------------------------------------------------------------GPEKEGEGHSYF----SSTKTLCVIDPE----------------------------------NRDSLEETDIDIATEDKSPIDT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14646-3", "uniprot_id": "PDE4B_RAT", "id": "P14646-3", "name": "3',5'-cyclic-AMP phosphodiesterase 4B", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKKSRSVMAVTADDNLKDYFECSLSKSYSSSSYTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDG------ISRPTTLPLTTLPSIAITTVSQE--------------------------------------------------------CFDVENG--PSPGRSPLDPQASSSSGLVLHAAFPG-------------------HSQRRESFLYRSDSDYDLSPKAMSRNSS-LPSE------------------------------------------------------------------------------QHGDDLIVTPFAQVLASLRIVRNNFTLLTNLH----------GAPNKRSPAASQAPVTRVSLQ------------------------------------EESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN-RELTHLSEMSRSGNQ-----------VSEYISNTFLDKQNDVEIPSPTQKDREKKK-------------------------------------------------------------------------------------------------------------KQQ-LMTQISGVKKLMHSS--------------------SLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDV-AYHNSLHAADVAQSTHVLLSTPALDAV--FTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQE-EHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVL-------------LLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKE--RERGMEIS-PMCDKHTA-SVEKSQVGFIDYIVHPLWETWADLV----------------------QPDAQDILDTLEDNRNWYQSMIPQSPSPPLDERSRD---CQGLM------EKFQFELTLEEEDSE--------------------------------------------------------------GPEKEGEGPNYF----SSTKTLCVIDPE----------------------------------NRDSLEETDIDIATEDKSLIDT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07343-1", "uniprot_id": "PDE4B_HUMAN", "id": "Q07343-1", "name": "3',5'-cyclic-AMP phosphodiesterase 4B", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKKSRSVMTVMADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDG------ISRPTTLPLTTLPSIAITTVSQE--------------------------------------------------------CFDVENG--PSPGRSPLDPQASSSAGLVLHATFPG-------------------HSQRRESFLYRSDSDYDLSPKAMSRNSS-LPSE------------------------------------------------------------------------------QHGDDLIVTPFAQVLASLRSVRNNFTILTNLH----------GTSNKRSPAASQPPVSRVNPQ------------------------------------EESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN-RELTHLSEMSRSGNQ-----------VSEYISNTFLDKQNDVEIPSPTQKDREKKK-------------------------------------------------------------------------------------------------------------KQQ-LMTQISGVKKLMHSS--------------------SLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDV-AYHNSLHAADVAQSTHVLLSTPALDAV--FTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQE-EHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVL-------------LLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKE--RERGMEIS-PMCDKHTA-SVEKSQVGFIDYIVHPLWETWADLV----------------------QPDAQDILDTLEDNRNWYQSMIPQSPSPPLDEQNRD---CQGLM------EKFQFELTLDEEDSE--------------------------------------------------------------GPEKEGEGHSYF----SSTKTLCVIDPE----------------------------------NRDSLGETDIDIATEDKSPVDT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JV44-1", "uniprot_id": "A0AC58JV44_DANRE", "id": "A0AC58JV44-1", "name": "Phosphodiesterase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRSRIQKHTHRCVNYKLIFPSNSFCPSVPDLSRRIVKGSPSKLYPEASLSRASKECQRSRPVQDRERKTSQKMRKSRSVLTVSPNEDSKEPPDSRLSESFTSSGCTLGVDLRRRRRRFSGNLQLPPLSWRQMERSRSPDDEF------MARPTTLPFITPPRIDITPVDTE--------------------------------------------------------CFDVENG--PSASCSPLDPQASPGSGLVLHTNFPG-------------------HNQRRESFLYRSDSDYDLSPKSMSRNSS-VASE------------------------------------------------------------------------------LHGDDLIVTPFAQVLASLRSVRNNFTVLTNVQ----------CTSNKRSPVSNQPSITRVCLP------------------------------------DESYQKLAVETMEELDWCLDQLETIQTYRSVSDMASNKFKRMLN-RELTHLSEMSRSGNQ-----------VSEFISNTFLDKQNDVEIPSPTPKAREKKK-------------------------------------------------------------------------------------------------------------KQQ-LMTQISGVKKVSHG---------------------PSLNCGIARFGVKTDKEDLLSKELEDLNRWGLNIFTVSEYSNNRPLTCIMYAIFQERDLLKTFKIPTDTFVTYMMTLEDHYHQDV-AYHNSLHAADVAQSTHILLSTPALDAV--FTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQE-DNCDIFQNLTKKQRTSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVL-------------LLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFHQGDRE--RERGMEIS-PMCDKHTA-SVEKSQVGFIDYIVHPLWETWADLV----------------------HPDAQDILDTLEDNRNWYQSMIPQSPSPPFYQPDKEGNGGSSGP------DKFQFELTLEEEDSE--------------------------------------------------------------GTEKDEQSQ--------GDEEEEAEEDR----------------------------------GEEMESTTHIQIVTEDASPVDT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3APY5-1", "uniprot_id": "A0A8M3APY5_DANRE", "id": "A0A8M3APY5-1", "name": "Phosphodiesterase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRKSQSVLAVTPVDDSKD-----LSG-CTSSGATLGVDLWRCPRRHSGTLVLPPLSWRQAERARSPQEDN------VSRPTSLGFITPPRIDITPVPPD--------------------------------------------------------SLEVENG--PSIGCSPLDLQVSPASGLILHPSMAS-------------------HSQRRESFLYRSDSDYDLSPKSTSRNSSLVGEQ------------------------------------------------------------------------------LHGEDLIVTPFAQVLASLRTVRNNFSILTNVS----------CPSSKRSPISSHGPVTKANLS------------------------------------DESYQKLALETMEELDWCLDQLETIQTYRSVSDMASNKFKRMLN-RELTHLSEMSRSGNQ-----------VSEFISNTFLDKQNELEIPLSTPKSRERKK-------------------------------------------------------------------------------------------------------------RQQQLMTQISGVRKVTHGSG-------------------PSSSCSTTRFGVKTDSEDMLSKDLEDINKWGLNIFKVAEHSHHRPLACIMYAIFQERDLMKTFKIPVDTFVTYMMTLEDHYHADV-AYHNSLHAADVAQSTHILLSTPALDAV--FTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQG-ENCDLFQNLSKKERQTLRKMVIHMVLATDMSKHMSLLADLKTMVETKKVTSSGVL-------------LLDNYTDRIQVLRNMVHCADLSNPTKPLDLYKQWTDRIMQEFFHQGDRE--RERGMEIS-PMCDKHTA-SVEKSQVGFIDYIVHPLWETWADLV----------------------HPDAQDILDTLEENRNWYYSMIPQSPSPPFFEA------GSPSG------DKFQFELEVEEGAKQ--------------------------------------------------------------DTKN-------------------------------------------------------------LSKTDCVEIVTHSTLFSET-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08499-1", "uniprot_id": "PDE4D_HUMAN", "id": "Q08499-1", "name": "3',5'-cyclic-AMP phosphodiesterase 4D", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAEGSSAPARAGSGEGSDSAGGATLKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQPQCPLQPPPPPPLPPPPPPPGAARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVETGH--RPGLKKSRMSWPSSFQGLRRFDVDNG--TSAGRSPLDPMTSPGSGLILQANFV--------------------HSQRRESFLYRSDSDYDLSPKSMSRNSS-IASD------------------------------------------------------------------------------IHGDDLIVTPFAQVLASLRTVRNNFAALTNLQ---------DRAPSKRSPMCNQPSINKATIT------------------------------------EEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLN-RELTHLSEMSRSGNQ-----------VSEFISNTFLDKQHEVEIPSP-TQKEKEKK-------------------------------------------------------------------------------------------------------------KRP--MSQISGVKKLMHSS--------------------SLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADV-AYHNNIHAADVVQSTHVLLSTPALEAV--FTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQE-ENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVL-------------LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRE--RERGMEIS-PMCDKHNA-SVEKSQVGFIDYIVHPLWETWADLV----------------------HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDP----EEGRQGQ-----TEKFQFELTLEEDGES--------------------------------------------------------------DTEKDSGS--------QVEEDTSCSDSKTLCTQDSE-----------STEIPLDEQV-----EEEAVGEEEESQPEACVIDDRSPDT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P14270-5", "uniprot_id": "PDE4D_RAT", "id": "P14270-5", "name": "3',5'-cyclic-AMP phosphodiesterase 4D", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAEGSSVPARAGSHEGSDSSGGAALKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQ----LQPPPPPPLPPPPPPPGATRGRYASSGAS-RVRHRGYSDTERYLYCRAMDRTSYAVETGH--RPGLKKSRMSWPSSFQGLRRFDVDNG--TSAGRSPLDPMTSPGSGLILQANFV--------------------HSQRRESFLYRSDSDYDLSPKSMSRNSS-IASD------------------------------------------------------------------------------IHGDDLIVTPFAQVLASLRTVRNNFAALTNLQ---------DRAPSKRSPMCNQPSINKATIT------------------------------------EEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLN-RELTHLSEMSRSGNQ-----------VSEYISNTFLDKQHEVEIPSP-TQKEKEKK-------------------------------------------------------------------------------------------------------------KRP--MSQISGVKKLMHSS--------------------SLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADV-AYHNNIHAADVVQSTHVLLSTPALEAV--FTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQE-ENCDIFQNLTKKQRQSLRKMAIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVL-------------LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRE--RERGMEIS-PMCDKHNA-SVEKSQVGFIDYIVHPLWETWADLV----------------------HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQ----EDGRQGQ-----TEKFQFELTLEEDGES--------------------------------------------------------------DTEKDSGS--------QVEEDTSCSDSKTLCTQDSE-----------STEIPLDEQV-----EEEAVAEEE-SQPQTGVADDCCPDT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01063-1", "uniprot_id": "PDE4D_MOUSE", "id": "Q01063-1", "name": "3',5'-cyclic-AMP phosphodiesterase 4D", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERDTCDVLSRSKS--ASEETLHSCNEEEDPFRGMEPYLVRRLSSRSIQLPPLAFRQLEQADLRSESE-----NIPRPTSLPLKILPLIAVTSADSS--------------------------------------------------------GFDVDNG--TSAGRSPLDPMTSPGSGLILQANFV--------------------HSQRRESFLYRSDSDYDLSPKSMSRNSS-IASD------------------------------------------------------------------------------IHGDDLIVTPFAQVLASLRTVRNNFAALTNLQ---------DRAPSKRSPMCNQPSINKATIT------------------------------------EEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLN-RELTHLSEMSRSGNQ-----------VSEYISNTFLDKQHEVEIPSP-TQKEKEKK-------------------------------------------------------------------------------------------------------------KRP--MSQISGVKKLMHSS--------------------SLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADV-AYHNNIHAADVVQSTHVLLSTPALEAV--FTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQE-ENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVL-------------LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRE--RERGMEIS-PMCDKHNA-SVEKSQVGFIDYIVHPLWETWADLV----------------------HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQ----EEGRQGQ-----TEKFQFELTLEEDCES--------------------------------------------------------------DTEKDSGS--------QVEEDTSCSDSKTLCTQDSE-----------STEIPLDEQV-----EEEAVAEEE-SQPETCVPDDCCPDT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32TUN7-1", "uniprot_id": "A0AB32TUN7_DANRE", "id": "A0AB32TUN7-1", "name": "Phosphodiesterase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAG-NEVTTLVSPGNVTDG------NAPKHLWRQQNPVSLQIQN---SLGSRKNYRVRQRGFSDTEK------YLNPRTMDRTYAVDTGTR-------------------------------------------PGLKKSRMSWPSSFQGLKRFDVDNG--TSSGRSPLDPMASPGSGLILQANFV--------------------HSQRRESFLYRSDSDYDLSPKSMSRNSS-IASD------------------------------------------------------------------------------IHGDDMIVTPFAQVLASLRTVRNNFAALTNVQQ--------ERSNNKRSPMCNPPPITKTSYTVLEVQTLKSKSTDAQLHKTQTKQANG--------DSEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLN-RELTHLSEMSRSGNQ-----------VSEYISSTFLDKQNEVEMPSPQSQKDKEKK-------------------------------------------------------------------------------------------------------------KRP--MSQISGVKKLTHSS--------------------SLTNSNIPRFGVKTETEDELAKELEDVNKWGLNVFKVSEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADV-AYHNNIHAADVTQSTHVLLSTPALEAV--FTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQE-ENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVL-------------LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRE--RERGMEIS-PMCDKHNA-SVEKSQVGFIDYIVHPLWETWADLV----------------------HPDAQDILDTLEDNREWYQSTIPQSPSPALDTS----SEGRRAAG----QEKFQFELTLEEDGES--------------------------------------------------------------DTEKDSGSPPEEDEEEEEEEENSCSDSKTLCTQDSE-----------CTEIPLDEQVGDVPHEDEYEHEENREISEPCVLEEEEEEEEEEEEDTANT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32U285-1", "uniprot_id": "A0AB32U285_DANRE", "id": "A0AB32U285-1", "name": "Phosphodiesterase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENMRQRDSL-ISSPLELQSKTSSAIRRRFSGPLLLPPLARRHSALDGKKLKDL-----EALYKSALAR---ADTQKET------------------------------------------------------------DFDVENG--LSMGRSSLD--PSPSSGLVLQAN-----------------------SQRRESFLYRSDSDFDLSPKTMSRNSS-TASE------------------------------------------------------------------------------LHGEDMIVTPFAQVLASLRTVRGNVAALTHMQ---------DRS-NKRPSGTNPQSACKTNLS------------------------------------DEAYQKLTVETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLN-RELTQLSETSRSGNQ-----------VSEFIASTILQKQYDVELLSA-ACKE-EKK-------------------------------------------------------------------------------------------------------------RRP--MSQISGVRKLSPSP--------------------SLPPTCIPRFGVNTQHESLLAKELEDLDRWGIDIFKIAEYSGNRPLTVMMYTIFQERDLLKTFKIPSDTFLTFLMTLEDHYHADV-AYHNNIHAADVVQSTHVLLSTPALEDV--FTDLEIMAALFASAIHDVDHPGVTNQFLINTNSELALMYNDASVLENHHLAVGFKLLQE-ENCDIFCNLSKKQRQSLRQMTIDMVLATDMSKHMNFLADLKTMVETKKVTSQGVL-------------LLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFSQGDRE--RDKGIDVS-PMCDKHTA-SMENTQVGFIDYIIHPLWETWADLV----------------------HPDAQDILDTLEDNREWYQSMIPRSPSPTPEEHDSRP-TGVTG----SAGEKFQFELTLEEE-----------------------------------------------------------------DGELETEEEHT-----DIERSRTMTDPEHPQTSP------------------LGITT----ILDSSERELDQELTSVSALQLETSSSSTHD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58HJ32-1", "uniprot_id": "A0AC58HJ32_DANRE", "id": "A0AC58HJ32-1", "name": "Phosphodiesterase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWMLWAWLDLQYFQVTLLTDMREWETVHLHATKPLQSHR--AVKRTFSGILQLPRLPRRLSAYGEYSSTTG-----KATFCIGLPNGLESDTPHGS------------------------------------------------------------SFDVENG--LSVGRSPLDSQASPGSGLVLQANFP--------------------HSQRRESFLYRSDSDFDLSPKAMSRNSS-TASE------------------------------------------------------------------------------LHGEDMIVTPFAQVLASLRTVRSNFAVLTHQQ---------DRVPSKKSTGNNPPSMCKTSLP------------------------------------EEPFQKLAVETLDELDWCLEQLETLKTRHSVSEMASNKFKRMLN-RELTQLSETSKSGNQ-----------VSEYISSTFLEKQHDMDIMST-PSKEKEKK-------------------------------------------------------------------------------------------------------------KRP--MSQISGVKKPTHSS--------------------NIAPSSIPRFGVSTNREDLLAKELEDFDRWGVDMFKISECSGNRPLTVAMYTTFQERDLLKSFKIPVDTFINYMTALEENYRSDV-AYHNSIHAADVVQSTHVLLSTPALEAV--FTDLEILAAMFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQE-ENCDIFQNLTKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVL-------------LLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDRE--RDKGMEIS-PMCDKHNA-SIEKSQVGFIDYIVHPLWETWADLV----------------------HPDAQEILDTLEDNREWYQSMIPHSPTSTPEDKSAVMGMGAMGGGIASAGDKFQFELTLEEEGES--------------------------------------------------------------DVESPVDEDLT-----SSTRDSSRTDPQGKQTSPAARLLSARSPGCRTMSFKMGEPP----DSEDEDKELDQEGKSVSCLRLGT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4T4-1", "uniprot_id": "PDE4A_DROME", "id": "Q9W4T4-1", "name": "3',5'-cyclic-AMP phosphodiesterase, isoform I", "aln": "MMRLARFTQGFSFNKNVAKHRGSGSSNGTGNGSGTGNGQGLGGSCSANGLAATGGVGGGGGSGSGGGGCGSGSGSGSGKRKSKARTKCFGGTVFRCCLPCRGGGSAAPATSPPQTPAQTPDELKVIPEDCNLEKSAEQKRDLLERNNKEDDLLNRTVSGSELDLYGGAGGGTKKHSLADTIDTSVTTPISLKTLINDVDEELDQQLSAADIAAASLASGLVARRAEPETLSDASVSPTAVVQQQQQQQQQLQQPLLQSQPHFVPSSGNILSQVTLYSGSNPSTNPCQSAVQNQGQNSNPNPNQNPNTNPNQNQQRCSCQPQTSPLPHIKEEEESDQANFKHQTSLKEHQPLPPPITIATGYCGSCESVHHSSATSSSAGTVPPGGQQTQEYIAGTSSTPSPRIKLKFRKPHKSCWSRIVLAPIGSAGGSSSATTVIGSNSNETLASSSTTGGTATTTQNSSSVSVAAHHRLTSSSASALATSHPSNSQLLPTSKMQAEQGSIGDLQKYHSRYLKNRRHTLANVRFDVENG---QGARSPLEG-GSPSAGLVLQNLP-----------------------QRRESFLYRSDSDFEMSPKSMSRNSS-IASERFKEQEASILVDR-----------------------------------------------------------------SHGEDLIVTPFAQILASLRSVRNNLLSLTNVPASN-----KSRRPNQSSSASRSGNPPGAPLS----------------------------------QGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLN-KELSHFSESSRSGNQ-----------ISEYICSTFLDKQQEFDLPSLRVEDNPELVAANAAAG------------------------------------------------------------------------------------------QQSAGQYARSRSPRGPPMSQISGVKRPLSHTN-------------------SFTGERLPTFGVETPRENELGTLLGELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDN-PFHNSLHAADVTQSTNVLLNTPALEGV--FTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQN-QGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVL-------------LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKE--RESGMDIS-PMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLV----------------------HPDAQDILDTLEENRDYYQSMIPPSPPPSGVDENPQ-------------EDRIRFQVTLEESDQEN-------------------------------------------------------------LAELEEGDE-------SGGESTTTGTTG--------------------------------TTAASALSGAGGGGGGGGGMAPRTGGCQNQPQHGGM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P70453-1", "uniprot_id": "PDE7A_MOUSE", "id": "P70453-1", "name": "High affinity 3',5'-cyclic-AMP phosphodiesterase 7A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGITLIWCLAL------VLIKWITSKRRGAISYDSS------------------------------------------------------DQTALYIRMLGDVRVRSRAGFETERRGSHPY--IDFRIFHSQSDIEAS-----------VSARNIRRLLSFQR---------------------------------------------------------------------------------------------------------------------------------YLRSSRVFRGATVCS---------------------------SLDILDEDYNGQAKCMLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMVKLRRFLVMIQEDYHSQN-PYHNAVHAADVTQAMHCYLKEPKLASS--VTPWDILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNSSVLENHHWRSAVGLLRE-S--GLFSHLPLESRQEMEAQIGALILATDISRQNEYLSLFRSHLDKGDLH-------------------LDDGRHRHLVLQMALKCADICNPCRNWELSKQWSEKVTEEFFHQGDIE--KKYHLGVS-PLCDRQTE-SIANIQIGFMTYLVEPLFTEWARFS---------------------DTRLSQTMLGHVGLNKASWKGLQRQQP-SSED--------------------------------------------------------------------------------------------------------------------------------------------------------------ANAAFELNSQLLTQENRLS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08593-1", "uniprot_id": "PDE7A_RAT", "id": "O08593-1", "name": "High affinity 3',5'-cyclic-AMP phosphodiesterase 7A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DQTALYIRMLGDVRVRSRAGFETERRGSHPY--IDFRIFHAQSEIEAS-----------VSARNIRRLLSFQR---------------------------------------------------------------------------------------------------------------------------------YLRSSRFFRGATVCR---------------------------SLNILDEDYNGQAKCMLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMVKLRRFLVMIQEDYHSQN-PYHNAVHAADVTQAMHCYLKEPKLANS--VTPWDILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRE-S--GLFSHLPLESRHEMEAQIGALILATDISRQNEYLSLFRSHLDKGDLH-------------------LDDGRHRHLVLQMALKCADICNPCRNWELSKQWSEKVTEEFFHQGDIE--KKYHLGVS-PLCDRQTE-SIANIQIGFMTYLQEPLFTEWARFS---------------------DTRLSQTMLGHVGLNKASWKGLQRQQP-SSED--------------------------------------------------------------------------------------------------------------------------------------------------------------ASAAFELNSQLLTQENRLS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13946-1", "uniprot_id": "PDE7A_HUMAN", "id": "Q13946-1", "name": "High affinity 3',5'-cyclic-AMP phosphodiesterase 7A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEVCYQLPVLPLDRPVP--------------------------------------------------------------------------------------------------------------------------------------------------------QHVLSRRGAISFSSSSALFG------CPNPRQLSQRRGAISYDSS------------------------------------------------------DQTALYIRMLGDVRVRSRAGFESERRGSHPY--IDFRIFHSQSEIEVS-----------VSARNIRRLLSFQR---------------------------------------------------------------------------------------------------------------------------------YLRSSRFFRGTAVSN---------------------------SLNILDDDYNGQAKCMLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMMKLRRFLVMIQEDYHSQN-PYHNAVHAADVTQAMHCYLKEPKLANS--VTPWDILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRE-S--GLFSHLPLESRQQMETQIGALILATDISRQNEYLSLFRSHLDRGDLC-------------------LEDTRHRHLVLQMALKCADICNPCRTWELSKQWSEKVTEEFFHQGDIE--KKYHLGVS-PLCDRHTE-SIANIQIGFMTYLVEPLFTEWARFS---------------------NTRLSQTMLGHVGLNKASWKGLQREQS-SSED--------------------------------------------------------------------------------------------------------------------------------------------------------------TDAAFELNSQLLPQENRLS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FFK5-1", "uniprot_id": "E7FFK5_DANRE", "id": "E7FFK5-1", "name": "Phosphodiesterase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELCYQLPVLPLDRPVP--------------------------------------------------------------------------------------------------------------------------------------------------------KHVLSRRGAISFSSSSSLFG------APDPRQLSQRRGAISYDSS------------------------------------------------------DQTALYIRMLGDVRVRSQVGFEPERRGSHPYLGIDFRTLHSRAESAGS-----------IPARRIRRLFSFQR---------------------------------------------------------------------------------------------------------------------------------HLLSSRLLRGAPHLN---------------------------PLHILDEDYCGQAKCMLEKVGSWNFDIFLFDRLTNGNSLVFLTFHLLSQYGLIELFQLDMVKVRRFLVLVQEDYHNQN-PYHNAVHAADVTQAMHCYLREPKLAQS--LTSFDILLGLLAAATHDLDHPGVNQPFLIKTNHYLAALYRNTSVLENHHWRSAVGLLRE-T--ELFSHLPAEDSLSIERQLGSLILATDISRQNEYLSRFRTHLDENDLN-------------------LGNASHRHFVLQMALKCADICNPCRPWELSKQWSEKVTEEFFHQGDIE--KKLKLEIS-PLCDSEAN-TIASVQIGFMTYVVEPLFAEWARFS---------------------DTRLSQTMLGHLGLNKASWSTMEPEASGSSEDGESDP---------------------------------------------------------------------------------------------------------------------------------------------------------ARSSEEPSSRALTQGSPES----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9QXQ1-1", "uniprot_id": "PDE7B_MOUSE", "id": "Q9QXQ1-1", "name": "3',5'-cyclic-AMP phosphodiesterase 7B", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSCLMVERCGEVLFESP------------------------------------------------------EQSVKCVCMLGDVRLRGQTGVPAERRGSYPF--IDFRLLNNTTHSGEI-----------GTKKKVKRLLSFQR---------------------------------------------------------------------------------------------------------------------------------YFHASRLLRGIIPQA---------------------------PLHLLDEDYLGQARHMLSKVGTWDFDIFLFDRLTNGNSLVTLLCHLFNSHGLIHHFKLDMVTLHRFLVMVQEDYHGHN-PYHNAVHAADVTQAMHCYLKEPKLASF--LTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRE-S--RLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLR-------------------LENVQDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGDLE--QKFELEIS-PLCNQQKD-SIPSIQIGFMTYIVEPLFREWARFTG--------------------NSTLSENMLSHLAHNKAQWKSLLSNQHRRRGSG--------------------------------------------------------------------------------------------------------------------------------------------------------------QDLAGPAPETLEQTEGATP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AIQ8-1", "uniprot_id": "A0A8I6AIQ8_RAT", "id": "A0A8I6AIQ8-1", "name": "Phosphodiesterase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPVLERYFHSAELGRRWTAP--------------------------------------------------------------------------------------------------------------------------------------------------------EAVLPSSLGSRPGCQQGPLPWDLPEMIRMVKLVWKSKSELQATKPR--------------------------------------------------GILENEDAFHGFPGDVRLRGQTGVPAERRGSYPF--IDFRLLNNTTHSGEI-----------GSKKKVRRLLSFQR---------------------------------------------------------------------------------------------------------------------------------HFHESRLLRGMTPQA---------------------------PLHLLDEDYLGQARHMLSKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNSHGLIHHFKLDMVTLHRFLVMVQEDYHGHN-PYHNAVHAADVTQAMHCYLKEPKLASF--LTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRE-S--RLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLR-------------------LENIQDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGDLE--QKFELEIS-PLCNQQKD-SIPSIQIGFMTYIVEPLFREWARFTG--------------------NSTLSESMLNHLAHNKAQWKSLLSNQHRRRGSG--------------------------------------------------------------------------------------------------------------------------------------------------------------QDPAGTAPETLEQTEGATP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NP56-1", "uniprot_id": "PDE7B_HUMAN", "id": "Q9NP56-1", "name": "3',5'-cyclic-AMP phosphodiesterase 7B", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSCLMVERCGEILFENP------------------------------------------------------DQNAKCVCMLGDIRLRGQTGVRAERRGSYPF--IDFRLLNSTTYSGEI-----------GTKKKVKRLLSFQR---------------------------------------------------------------------------------------------------------------------------------YFHASRLLRGIIPQA---------------------------PLHLLDEDYLGQARHMLSKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQN-PYHNAVHAADVTQAMHCYLKEPKLASF--LTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRE-S--RLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLR-------------------LEDAQDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGELE--QKFELEIS-PLCNQQKD-SIPSIQIGFMSYIVEPLFREWAHFTG--------------------NSTLSENMLGHLAHNKAQWKSLLPRQHRSRGSSGSGP---------------------------------------------------------------------------------------------------------------------------------------------------------DHDHAGQGTESEEQ-EGDSP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64338-3", "uniprot_id": "PDE1C_MOUSE", "id": "Q64338-3", "name": "Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MESPTKEIEEFE----------------------------------SNSLKHLQ-------------------------------------------------------------------------PEQIEKIWLRLRGLRKYKKTSQRLRSLVK-------------------QLERGEASVVDLKKNLEYAATVLESVYIDETR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMG-MMLRRSDEKPRFKSI-----------VHAVQAGIFVERMYR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------RTSNMVGLSYPPAVIDALKDVDTWSFDVFSLNEASGDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTVHYLLYKTGVANW--LTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENHHLSAAYRLLQEDEEMNILVNLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPEA------------------------IEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDRE--AELGLPFS-PLCDRKST-MVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLI-------------DESSQTGGTGQRRSSLNSIN----SSDAKRSGVKSSGSDGSAPINNSVIPVDYKSFKATWTEVVQIN------------------------------------------------------------RERWRAKVPKE----------------------------------------------------EKAKKEAEEKARLAAEEKQKEMEAKSQAEQGTTSKGEKKTSGEAKSQVNGTR--KGDNPRGKNSKGEK-AGEKQQNGDLKDGKNKADKKDHSNTGNESKKTDGTKKRSHGSPAPSTSSTSRITLPVIKPPLRHFKRPAYASSSYAPSVPKKTDDHPVRYKMLDQRIKMKKIQNISHHWNKK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14123-1", "uniprot_id": "PDE1C_HUMAN", "id": "Q14123-1", "name": "Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MESPTKEIEEFE----------------------------------SNSLKYLQ-------------------------------------------------------------------------PEQIEKIWLRLRGLRKYKKTSQRLRSLVK-------------------QLERGEASVVDLKKNLEYAATVLESVYIDETR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMG-MMLRRSDEKPRFKSI-----------VHAVQAGIFVERMYR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------RTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEASGDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTVHYLLYKTGVANW--LTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENHHLSAAYRLLQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPEA------------------------IEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDRE--AELGLPFS-PLCDRKST-MVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLI-------------DETSQTGGTGQRRSSLNSIS----SSDAKRSGVKTSGSEGSAPINNSVISVDYKSFKATWTEVVHIN------------------------------------------------------------RERWRAKVPKE----------------------------------------------------EKAKKEAEEKARLAAEEQQKEMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGEQQQNGDFKDGKNKTDKKDHSNIGNDSKKTDGTKQRSHGSPAPSTSSTCRLTLPVIKPPLRHFKRPAYASSSYAPSVSKKTDEHPARYKMLDQRIKMKKIQNISHNWNRK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63421-1", "uniprot_id": "PDE1C_RAT", "id": "Q63421-1", "name": "Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDTSHKKEGFKKCRSATFSIDGYSFTIVANEAGDKNARPLARFSRSKSQNCLWNSLIDGLTGNVKEKP-----------------------------------------------RPTIVQDTRPPEEILADELPQLDSPEALVKTSFRLRSLVK-------------------QLERGEASVVDLKKNLEYAATVLESVYIDETR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMG-MMLRRSDEKPRFKSI-----------VHAVQAGIFVERMYR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------RTSNMVGLSYPPAVIDALKDVDTWSFDVFSLNEASGDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTVHYLLYKTGVANW--LTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENHHLSAAYRLLQEDEEMNILVNLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPEA------------------------IEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDRE--AELGLPFS-PLCDRKST-MVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLI-------------DETSQTGGTGQRRSSLNSIN----SSDAKRSGVKSSGSEGSAPINNSVIPVDYKSFKATWTEVVQIN------------------------------------------------------------RERWRAKVPKE----------------------------------------------------EKAKKEAEEKARLAAEEKQKEMEAKSQAEQGTTSKAEKKTSGETKGQVNGTRTSKGDNPRGKNSKGDK-AGEKQQNGDLKDGKNKADKKDHSNTGNESKKADGTKKRSHGSPAPSTSSTSRLTLPVIKPPLRHFKRPAYASSSYAPSVPKKTDDHPVRYKMLDQRIKIKKIQNISHHWNKK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61481-4", "uniprot_id": "PDE1A_MOUSE", "id": "Q61481-4", "name": "Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSTDTDIEELEN----------------------------------ATYKYLIG-------------------------------------------------------------------------EQTEKMWQRLKG---------ILRCLVK-------------------QLEKGDVNVVDLKKNIEYAASVLEAVYIDETR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLLDTEDELSDIQTDSVPSEVRDWLASTFTRKMG-MMKKKPEEKPKFRSI-----------VHAVQAGIFVERMYR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------KNYHMVGLTYPAAVIVTLKEVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLIAFAEALEVGYSKHKNPYHNLVHAADVTQTVHYIMLHTGIMHW--LTELEILAMVFAAAIHDYEHTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQE-EEMNILVNLSKDDWRDLRNLVIEMVLATDMSGHFQQIKNIRNSLQQPEG------------------------IDRAKTMSLILHAADISHPAKTWKLHYRWTMALMEEFFLQGDKE--AELGLPFS-PLCDRKST-MVAQSQIGFIDFIVEPTFSLLTDSTEKIVIPLI-------------EEASKSQSSNYGASSSSTMIGFHVADSLRRSNTKGSVCDGSYAPDYSLSAVDLKSFKNNLVDIIQQN------------------------------------------------------------KERWKELAAQG----------------------------------------------------ELDLHKNSEELGNTEEKHADTRP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5Y792-1", "uniprot_id": "A0A8I5Y792_RAT", "id": "A0A8I5Y792-1", "name": "Phosphodiesterase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MITASLDGHTLSITTCGALGNIIMGSTDTDIEELEN----------------------------------ATYKYLIG-------------------------------------------------------------------------EQTEKMWQRLKG---------ILRCLVK-------------------QLEKGDVNVVDLKKNIEYAASVLEAVYIDETR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLLDTEDELSDIQTDSVPSEVRDWLASTFTRKMG-MTKKKPEEKPKFRSI-----------VHAVQAGIFVERMYR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------KNYHMVGLTYPAAVIVTLKEVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLIAFAEALEVGYSKHKNPYHNLVHAADVTQTVHYIMLHTGIMHW--LTELEILAMVFAAAVHDYEHTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQE-EEMNILVNLSKDDWRDLRNLVIEMVLATDMSGHFQQIKNIRSSLQQPEG------------------------IDRAKTMSLILHAADISHPAKTWKLHYRWTMALMEEFFLQGDKE--AELGLPFS-PLCDRKST-MVAQSQIGFIDFIVEPTFSLLTDSTEKIVIPLI-------------EEASKPESSNYGASSSSTMIGFHVADALRRSNTKGCMSDGTYAPDYSLSAVDLKSFKNNLVDIIQQN------------------------------------------------------------KERWKELAAQG----------------------------------------------------ELDLHKNSEDL---EEKHADTHP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54750-1", "uniprot_id": "PDE1A_HUMAN", "id": "P54750-1", "name": "Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSSATEIEELEN----------------------------------TTFKYLTG-------------------------------------------------------------------------EQTEKMWQRLKG---------ILRCLVK-------------------QLERGDVNVVDLKKNIEYAASVLEAVYIDETR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLLDTEDELSDIQTDSVPSEVRDWLASTFTRKMG-MTKKKPEEKPKFRSI-----------VHAVQAGIFVERMYR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------KTYHMVGLAYPAAVIVTLKDVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLITFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHW--LTELEILAMVFAAAIHDYEHTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQE-EEMNILINLSKDDWRDLRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPEG------------------------IDRAKTMSLILHAADISHPAKSWKLHYRWTMALMEEFFLQGDKE--AELGLPFS-PLCDRKST-MVAQSQIGFIDFIVEPTFSLLTDSTEKIVIPLI-------------EEASKAETSSYVASSSTTIVGLHIADALRRSNTKGSMSDGSYSPDYSLAAVDLKSFKNNLVDIIQQN------------------------------------------------------------KERWKELAAQE----------------------------------------------------ARTSSQKCEFI------HQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HXQ5-1", "uniprot_id": "A0AC58HXQ5_DANRE", "id": "A0AC58HXQ5-1", "name": "Phosphodiesterase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSVTSAFTRSRNTLVKVGSEPQKEPDGKPRTGTAVRAKHKSRQSLVQKTTGSSRANTPQTATVANEDGETNSRPLARFARSKSQSALWNTLTAGTSKKEKGKA-----------------------------------------------QRDVPDDPQRIEEILADELPSTDTPEATEKTAVRLRCLVK-------------------QLERGEASLVDLKKNLEYAATVLESVYIEETR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLVDTEDELSDIQSDSVPSEVRDWLASTFTRQMG-LMLRRTEEKPRFRSI-----------VHAVQAGIFVERMYR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------RTSNMVGLSYPPNVIAVLKNVDRWSFDVFALNESSGDHALKFIFYELLTRYDLISRFKIPVSALVSFVEALEVGYSKYKNPYHNLIHAADVTQTVHYLLLKTGMVHW--MTELEIFAMIFAAAIHDYEHTGTTNNFHIQTRSDAAILYNDRSVLESHHVSASYRLLQDDDEMNILYNLSKDDWREFRALVVEMVLATDMSCHFQQVKAMKNYLQQPEG------------------------IDKPKAISLLLHAADISHPAKTWDLHHRWTTSLLEEFFLQGDKE--AELGLPFS-PLCDRKST-MVAQSQIGFIDFIVVPTFTVLTDMTEKIVTPLI-------------EEATSSGLSGFRSITG---------GDVKRSSVNSSASDSSSSHNGSLLTVDLKNFKALWNEEVSLN------------------------------------------------------------RERWKMQAAKETE--------------------------------------------------EKAKRELEEQQEVENQVQKKELELS-----------------------------------------------------------------------EPKKDDPEPGVVNGPPEES---------------------PHGKSKKLQNGILLKSDFYSSNCSLFIHDCHDWIIQNITNN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q01065-1", "uniprot_id": "PDE1B_MOUSE", "id": "Q01065-1", "name": "Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELSPRSPPEML-------------------------------ESDCPSPLELKS-------------------------------------------------------------------------APSKKMWIKLRS---------LLRYMVK-------------------QLENGEVNIEELKKNLEYTASLLEAVYIDETR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QILDTEDELRELRSDAVPSEVRDWLASTFTQQTR-AKGRRAEEKPKFRSI-----------VHAVQAGIFVERMFR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------RTYTSVGPTYSTAVHNCLKNLDLWCFDVFSLNRAADDHALRTIVFELLTRHSLISRFKIPTVFLMSFLEALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHC--LSEIEVLAIIFAAAIHDYEHTGTTNSFHIQTKSECAILYNDRSVLENHHISSVFRMMQD-DEMNIFINLTKDEFAELRALVIEMVLATDMSCHFQQVKTMKTALQQLER------------------------IDKSKALSLLLHAADISHPTKQWSVHSRWTKALMEEFFRQGDKE--AELGLPFS-PLCDRTST-LVAQSQIGFIDFIVEPTFSVLTDVAEKSVQPLA-------------DDDSKPKSQP--------------SFQWRQPSLDVDVGDPNP---------DVVSFRATWTKYIQEN------------------------------------------------------------KQKWKERAASG----------------------------------------------------ITNQMSIDELSPCEEEAPSSPAEDEHNQNGNLD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01066-1", "uniprot_id": "PDE1B_RAT", "id": "Q01066-1", "name": "Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELSPRSPPEML-------------------------------ESDCPSPLELKS-------------------------------------------------------------------------APSKKMWIKLRS---------LLRYMVK-------------------QLENGEVNIEELKKNLEYTASLLEAVYIDETR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QILDTEDELRELRSDAVPSEVRDWLASTFTQQTR-AKGRRAEEKPKFRSI-----------VHAVQAGIFVERMFR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------RTYTAVGPTYSTAVHNCLKNLDVWCFDVFSLNRAADDHALRTIVFELLTRHSLISRFKIPTVFLMSFLEALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHC--LSEIEVLAIIFAAAIHDYEHTGTTNSFHIQTKSECAILYNDRSVLENHHISSVFRMMQD-DEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLER------------------------IDKSKALSLLLHAADISHPTKQWSVHSRWTKALMEEFFRQGDKE--AELGLPFS-PLCDRTST-LVAQSQIGFIDFIVEPTFSVLTDVAEKSVQPLT-------------DDDSKSKSQP--------------SFQWRQPSLDVDVGDPNP---------DVVSFRSTWTKYIQEN------------------------------------------------------------KQKWKERAASG----------------------------------------------------ITNQMSIDELSPCEEEAPSSPAEDEHNQNGNLD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01064-1", "uniprot_id": "PDE1B_HUMAN", "id": "Q01064-1", "name": "Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELSPRSPPEMLE------------------------------ESDCPSPLELKS-------------------------------------------------------------------------APSKKMWIKLRS---------LLRYMVK-------------------QLENGEINIEELKKNLEYTASLLEAVYIDETR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QILDTEDELQELRSDAVPSEVRDWLASTFTQQAR-AKGRRAEEKPKFRSI-----------VHAVQAGIFVERMFR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------RTYTSVGPTYSTAVLNCLKNLDLWCFDVFSLNQAADDHALRTIVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHC--LSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQD-DEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLER------------------------IDKPKALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKE--AELGLPFS-PLCDRTST-LVAQSQIGFIDFIVEPTFSVLTDVAEKSVQPLA-------------DEDSKSKNQP--------------SFQWRQPSLDVEVGDPNP---------DVVSFRSTWVKRIQEN------------------------------------------------------------KQKWKERAASG----------------------------------------------------ITNQMSIDELSPCEEEAPPSPAEDEHNQNGNLD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7YZV4-1", "uniprot_id": "PDE1_DROME", "id": "B7YZV4-1", "name": "Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQPSSPNATNYLADNIQISSANLSQTEMVVGRDSADYTAMHSINVGVGNSFLRGDTDIPQESG--------HSFETPSNMSFTAG------------------------------------------------------------------------QWDTESLPPVDTPDALNKAAGRIRSLLR-------------------RMDHETVAYEDMQRNLHYAARVLEAVFIDESREGCNGNCKNLNCSRHSHGRDDQQQDNNNSNRSCSLQEASPGGAGAGVTPGADNQDSIESRTKGVSQAPQTHSGPTGPPSNTSSETIAQPAPKLQPALETVRESVMEESPSKDPGDKGPPPPASTSTLTSQTTTSSSATAEPSAKAAESQAGSAGSSGSCSNPAAVHRQRRLRT---PTWARSMSTNKTRLADEDDELSEVQPDAVPPEVREWLASTFTRQMA-TSRRKSDEKPKFRSV-----------AHAIRAGIFVDRMYR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVSSSALTAFPPDVVRLLKNLDDWTFDVFALTEAASGQVVKYVAYELFNRYGSIHKFKIAPGILEAFLHRVEEGYCRYRNPYHNNLHAVDVMQTIHYCLCNTGLMNW--LTDLEIFASLLAALLHDYEHTGTTNNFHVMSGSETALLYNDRAVLENHHASASFRLLRE-DEYNILSHLSREEFRELRGLVIEMVLGTDMTNHFQQMKAMRQLLTLQEAT-----------------------IDKQKVLSLVLHCCDISHPAKQWGVHHRWTMLLLEEFFRQGDLE--KELGLPFS-PLCDRNNT-LVAESQICFIDFIVEPSMGVMSDMLELILAPIAPMNKSKPATLVEHETTANSTTNSAIVIPNSGITPSMDKPRDHRTEAKTTAAECLARKSVTGTTASKFNIPKPWLTCLVEN------------------------------------------------------------KRIWKEQAVKDAE--------------------------------------------------ARALATAAEEAAAAAAAEAEESKPETETADG-------------------------------------------------------------------EQSEPAAEPADGAAA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E9Q4S1-1", "uniprot_id": "PDE8B_MOUSE", "id": "E9Q4S1-1", "name": "High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGCAPS-------------------------------IHVSQSGVIYCRDSDESNSPRQTSSVSQGPTAPLHGLFV--------------QTDAADAMPPSRAAGPPGAVRVRRSRAELGSGSSTGSSGPATTTCRGRRRHCCSSAEAETQTSYTSVK--------------------VLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLD-----KHHEIIVIDHRQSRNFDAEAVCRSIRATNPSEHTVILAVVSQASD-----------------------------------------DHEEASVLPLLHAGFNRRFMENSSIIACYNELIQIEHGEVRSQFKLR-------------------ACNSVFTALDHCHEAIEITSDDHVIQYVNPAFERMMG--------------------------------------------------------------------------YHKGELLGKELADLPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVKITPVIGQGGKIRHFVSLKKLCCTTDSNKQIHRIHRD---SGDNSQTEPHSFRHKSRRKESIDVKSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINI-----------INAAQENSPVTVAEALDRVLEILRTTELYSPQLGT---------------------------------------------------------------------------------------------------------KDEDPHTSDLVGGLMTDG---LRRLSGNEYVFTKNVHH--SHSHLSMPITINDVPPSIAQLLDNEESWDFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLNCTETTLRAWLQVIEANYHSSN-AYHNSTHAADVLHATAFFLGKERVKGS--LDQLDEVAALIAATVHDVDHPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPLAAESE------GSDCECNPTGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEE--KRQGLPVVMPVFDRNTC-SIPKSQISFIDYFITDMFDAWDAFA------------------------HLPALMQHLADNYKHWKTLDDLKCKTLRLPSDS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZTX5-1", "uniprot_id": "A0A8I5ZTX5_RAT", "id": "A0A8I5ZTX5-1", "name": "Phosphodiesterase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGCAPS-------------------------------IHVSQSGVIYCRDSDESNSPRQTSSVSQGPTAPLHGLFV--------------QTDAADAMPPSRAAGPPGAVRVRRSRAELGSGSSTGSSGPAATTCRGRRRHCCSSAEAETQTSYTSVKQVSSAEVRIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLD-----KHHEIIVIDHRQTRNFDAEAVCRSIRATNPSEHTVILAVVSQASD-----------------------------------------DHEEASVLPLLHAGFNRRFMENSSIIACYNELIQIEHGEVRSQFKLR-------------------ACNSVFTALDHCHEAIEITSDDHVIQYVNPAFERMMG--------------------------------------------------------------------------YHKGELLGKELADLPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVKITPVIGQGGKIRHFVSLKKLCCTTDSSKQIHRIHRD---SGDNSQTEPHSFRHKSRRKESIDVKSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINI-----------INAAQENSPVTVAEALDRVLEILRTTELYSPQLGT---------------------------------------------------------------------------------------------------------KDEDPHTSDLVGGLMTDG---LRRLSGNEYVFTKNVHH--SHSHLSMPITINDVPPSIAQLLDNEESWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCTETTLRAWLQVIEANYHSSN-AYHNSTHAADVLHATAFFLGKERVKGS--LDQLDEVAALIAATVHDVDHPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPLAAESE------GSDCECNPTGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEE--KRQGLPVVMPVFDRNTC-SIPKSQISFIDYFITDMFDAWDAFA------------------------HLPALMQHLADNYKHWKTLDDLKCKSLRLPSNS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95263-1", "uniprot_id": "PDE8B_HUMAN", "id": "O95263-1", "name": "High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGCAPS-------------------------------IHVSQSGVIYCRDSDESSSPRQTTSVSQGPAAPLPGLFV--------------QTDAADAIPPSRASGPPSVARVRRARTELGSGSSAGSAAPAATTSRGRRRHCCSSAEAETQTCYTSVKQVSSAEVRIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLD-----KHHEIIVIDHRQTQNFDAEAVCRSIRATNPSEHTVILAVVSRVSD-----------------------------------------DHEEASVLPLLHAGFNRRFMENSSIIACYNELIQIEHGEVRSQFKLR-------------------ACNSVFTALDHCHEAIEITSDDHVIQYVNPAFERMMG--------------------------------------------------------------------------YHKGELLGKELADLPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVKITPVIGQGGKIRHFVSLKKLCCTTDNNKQIHKIHRD---SGDNSQTEPHSFRYKNRRKESIDVKSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINI-----------INAAQENSPVTVAEALDRVLEILRTTELYSPQLGT---------------------------------------------------------------------------------------------------------KDEDPHTSDLVGGLMTDG---LRRLSGNEYVFTKNVHQ--SHSHLAMPITINDVPPCISQLLDNEESWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAWFQVIEANYHSSN-AYHNSTHAADVLHATAFFLGKERVKGS--LDQLDEVAALIAATVHDVDHPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIE------GSDCECNPAGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEE--KRQGLPVVMPVFDRNTC-SIPKSQISFIDYFITDMFDAWDAFA------------------------HLPALMQHLADNYKHWKTLDDLKCKSLRLPSDS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AWN1-1", "uniprot_id": "A0A8M3AWN1_DANRE", "id": "A0A8M3AWN1-1", "name": "Phosphodiesterase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGCAPS-------------------------------IHVSQSGVIYCRDSDESNSPHQTTTISQGTATTLHGLFI--------------KTDAADTIPSVIAY------QTRHTRTNSHRERRENSGGQMCT-------------EAETQTSCTSVK-VSGAEDRLGPMRLSHEPIQVLLVFAKEDSQSDAFWWACERAAFRCNIARTPESALECFLD-----KHHEIVIIDGRHPRYFEAEAICRMIRATKLSEHTVILAVMPQTPS-----------------------------------------DQEEPSVLPLLSAGFSRRYLENSSVSACYNELIQLEHGEVRAQFKLR-------------------ACNAVFTALEQCQEAVEISSEDHVIQYVNPAFEKMMG--------------------------------------------------------------------------YHRGELIGKELTELPRSDKNSADLLDTINTCIKKGKEWQGIYFSRRKSGDSIQQYVKITPVVGQGGKIRHFVSIKRPYS--DNHRQVHKLSKEEKCCGEHSQSECNSLRHKDRRKESVDVRSISSHSSDAPSLQNRRYSSMARIHSMTIEAPITKVINI-----------INAAQESSPVTVAEALDRVLEILRTTELYSPQLAS---------------------------------------------------------------------------------------------------------KEDDPHTNDLVGGLMSDG---LRRLSGNEYIFSKSALQNMSQSQLGVPVPLNDIPPSIAELLNEEEQWEFNILELEAATHKRPLSYLGLKIFSAFGVCEFLNCSESTLRLWLQVIETNYHSSN-SYHNSTHAADVLHATAYFLRKERVKAS--LDQLDEVAALLAATVHDVDHPGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTVRDSKCNIFKNMERTQFRTLRQAIIDMVLATEMTRHFEHVNKFVNSINKPMSAIEETSSNSEGSDCEGQASIRNSPENRLLIKRMLIKCADVANPCRPLELCIEWAGRISEEYFAQTDEE--KRQGLPVVMPVFDRNTC-SIPKSQISFIDYFITDMFDAWDAFA------------------------SLPGLMEHLAENYKYWKNLDEMKCKSLRPPPPP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O88502-1", "uniprot_id": "PDE8A_MOUSE", "id": "O88502-1", "name": "High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGCAPS-------------------------------IHTSENRTFSHSDGEDEDVDVDVPGPAPR------------------------SIQRWSTAP-----------------GLVEPQPRDNGAS---------------------KVSVADVQ--------FGPMRFHQDQLQVLLVFTKEDSQCNGFHRACEKAGFKCTVTKEVQTVLTCFQD-----KLHDIIIIDHRYPRQMDAETLCRSIRSSKFSENTVIVGVVRRV-------------------------------------------DKEESSLMPFLAAGFTRRFIENPNVMACYNELLQLACGEVRSQLKLR-------------------ACNSVFTALEKSQEAIEITSEDHIIQYANPAFESTMG--------------------------------------------------------------------------YQSGELIGKELAQVPINEK-KGDLLDAINSCVTVDKEWQGVYHTQKKNGDNIQQNVKIIPVIGQGGKIRHYVSIIRVCNGNNKVETTTECVQT-----DSQTDN-QAGKHKDRRKHSMDAKAVSSRTSDVSS--QRRHSSLARIHSMMIEAPITKVINI-----------INAAQENSPVPVTEALNRVLDILRTTELYSPQFNA---------------------------------------------------------------------------------------------------------QDD-PHATDLVGGLMSDG---LRRFSGNEYILATKNLP-PLSNNLATPVSLHDVPPRIALAIENEEQWDFDIFELEVATQNRPLIYLGLKTFARFGMCEFLQCSETTLRSWFQMIESNYHSSN-PYHNSTHAADVLHATAYFLSRDKIKET--LDRIDEVAALIAATVHDVDHPGRTNSFLCNAGNQLAVLYNDTAVLESHHVALAFQLTLENDQCNIFKQMERNDYRTLRQSIIDMVLATEMTKHFEHVNKFINSINKPLTAQESE---EPDRSLEDIKAMLKTPESRALIKRMMIKCADVSNPCRPLEHCIEWAARISEEYFSQTDEE--KQLDLPVVMPVFDRNTC-SIPKSQISFIDYFITDMFDAWDAFV------------------------DLPNLMQHLDDNFRYWKGLDEKKLRSLRPPPE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60658-1", "uniprot_id": "PDE8A_HUMAN", "id": "O60658-1", "name": "High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGCAPS-------------------------------IHIS-ERLVAEDAPSPAAPPLSSGGPRLP------------------------QGQKTAALPR------------TRGAGLLESELRDGSGK---------------------KVAVADVQ--------FGPMRFHQDQLQVLLVFTKEDNQCNGFCRACEKAGFKCTVTKEAQAVLACFLD-----KHHDIIIIDHRNPRQLDAEALCRSIRSSKLSENTVIVGVVRRV-------------------------------------------DREELSVMPFISAGFTRRYVENPNIMACYNELLQLEFGEVRSQLKLR-------------------ACNSVFTALENSEDAIEITSEDRFIQYANPAFETTMG--------------------------------------------------------------------------YQSGELIGKELGEVPINEK-KADLLDTINSCIRIGKEWQGIYYAKKKNGDNIQQNVKIIPVIGQGGKIRHYVSIIRVCNGNNKAEKISECVQS-----DTHTDN-QTGKHKDRRKGSLDVKAVASRATEVSS--QRRHSSMARIHSMTIEAPITKVINI-----------INAAQESSPMPVTEALDRVLEILRTTELYSPQFGA---------------------------------------------------------------------------------------------------------KDDDPHANDLVGGLMSDG---LRRLSGNEYVLSTKNTQ-MVSSNIITPISLDDVPPRIARAMENEEYWDFDIFELEAATHNRPLIYLGLKMFARFGICEFLHCSESTLRSWLQIIEANYHSSN-PYHNSTHSADVLHATAYFLSKERIKET--LDPIDEVAALIAATIHDVDHPGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQGIIDMVLATEMTKHFEHVNKFVNSINKPLATLEENG--ETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFSQTDEE--KQQGLPVVMPVFDRNTC-SIPKSQISFIDYFITDMFDAWDAFV------------------------DLPDLMQHLDNNFKYWKGLDEMKLRNLRPPPE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HUM1-1", "uniprot_id": "A0AC58HUM1_DANRE", "id": "A0AC58HUM1-1", "name": "Phosphodiesterase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGCASS-------------------------------IHIS-DRVVYHSGKESEEPPHTHS-------------------------------HTHTCTP--------------------DTGDRSSAGG---------------------QGSLTELQ--------FGPMKLNEDQLQVLLVFARDDAQSSSFISACERCGFGCSVCRTPEAALECVLQ-----KSPDLIIIDHRHPRGLDGEALCRSIRAVSCSHNTVIVAVVKRP-------------------------------------------DREEATVMPLISAGFNRRFVENSSMMSCYNELLQLHHGEIRAQIKLR-------------------ACNALFTALEQSQEAIEISSEDHIIQYVNPAYECMMG--------------------------------------------------------------------------YQCGELL-KENTEVPKSERNRPDLLDNISSCMLRGKEWQGVYYAKKKNGDSVQQNVRMTPVIGQGGKVRHCVSVNRPLNDHNKTEKSCERVQA-----ESQTDIPQSSKHKDRRKGSLDVRSTTSRGSDAGSS-QRRHSSMARIHSMTIEAPITKVINI-----------INAAQESSPLPVAEALDRVLEILRSSELYSPQLAT---------------------------------------------------------------------------------------------------------KEEDPHTNDLVGGLMTDG---LRRLSGNEYIFTTKQLH-HMTSHQTTPLSLNDIPQCIAQTMENEDSWDFDIFNLESATLKRPLAFLGLKLFSRFGVCEFLGCAEATLRSWLQNIEASYHGSN-PYHNSTHAADVLHATAYFLCKERVKQS--LDPIDEVAALIAAAVHDVDHPGRTNSFLCNAGSELAVLYNDTAVLESHHAALAFQITTRDDKSNIFRNMERNEYRTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPLAALEENG--GSDDE-DSVKSVLTSPENRILVKRMLIKCADISNPCRPLELCIEWAGRISEEYFAQTDEE--KQRGLPVVMPVFDRHTC-SIPKSQISFIDYFITDMFDAWDAFA------------------------DLPNLMQHLDNNFKYWKSLDEQKLRSLRAPPEEHA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6NNF2-1", "uniprot_id": "PDE8_DROME", "id": "Q6NNF2-1", "name": "High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGCSPSTLPPAPSAGQTGERGSLPLDASEKDESRLFCIKLRRSRLRRCSCGGVTLQPPSDGNGSTAGDNLCGQVLLNPLQTKSEADYEKLSTGKKDSIVTVAALGNFTHSVVRRATGSTGTSGTSSSGGNSRP----GHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPNPPLKALLVFHKSDSICEAITAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSSKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFF-----------------------------------------EKDD-VLIALLDAGVNRCVAETTNLAMCSVELKQILHSIIRPHNVMS-------------------TQQALYTALHRLKEVVLITDDLLRIQYANRATERLLN--------------------------------------------------------------------------MRLDEIISKQLEDIFVSDL------STISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVPG--GQMDFIATLPQP--------KEAPRGSLHSVRR-CSFDVRSIASDG--------LRRTSLAKLTSLPLEAPITKIINL-----------LSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEI--------------------------------------------------------------------------------------------------------RTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRTGSST---RTAAIVPAKMKSNP-IIMELLDESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSN-TYHNSTHAADVMQATGAFITQLTNKDMLVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGG---------------EEPRDHNPQTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEE--KQRHLPIVMPMFDRATC-SIPKSQIGFIEYIIQDMMHAWESFI------------------------DMPQLITYMQINYSQWKKYDEQGVNTLAEIMAKQPPVGKMANSK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJ79-1", "uniprot_id": "PDE11_DROME", "id": "Q9VJ79-1", "name": "Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11", "aln": "---------------------------------------------------------------------------------------------------------------------------------MGQAASMCRFRGCRYKNKNKSSKQQQQQQQQQQQQQQQHQQQQQQTPSHSPQIQHHSEIIPATTGLHLRSIEEPATTPLQFQPTGRMNTEQGGTGYGGYGSSEHSLLIATRHAGVPLPLAQHQPLPAHYQPLNHSGAAPPSSSNGSSSSGGGVQTSATPQQQQQYQVQQPYQYQYQHHYHHQANSPQHHRPYDPEHARMEAWLDENQEFVQDYFIRKATRQTVDAWLVSHATSAGNDVVSSTSPTHANGQTSSSRGGSGATTPVRKISAHEFERGGLLKPIVNTIDGTPTFLSIGPPMDNGSVGGSCSNLQNVGGVVAGQYQYNHQQHHHNHAHLHHSQHSHYQAGGAVGSSSLGSTGGASGAGGAPSLGGSGGAGNGHQYPYYHCHQRPQRLSRNELKQLDEKELIFELVKDICNELEVRTLCHKILQNVSILLNADRGSLFLVQGRCNGPDGLKKCLVSKLFDVCPRSTVEEMEQQDEVRVAWGTGIAGHVAESGEPVN-------------------------------------------------------IPDAYQDERFNCEIDSLTGYRTKALLCMPIKDSSGDVIGVAQVINKMNGECFSEIDEKVFSSYLQFCGIGLRNAQLYEKSQLEIKRNQVLLDLARMIFEEQSTIEHMVFRILTHMQSLIQCQRVQILLVHEADKGSFSRVFDFEANDLSEEEATSRTSPYESRFPINIGITGHVATTGETVNVPNAYEDDRFDASVDENSCFKHRSILCMAIKNSLG-------------------------------------------------------------------------------QIIGVIQLINKFNELDFTKNDENFVEAFAIFCGMGIHNTHMYEKAIVAMAKQSVTLEVLSYHASATMDEAHRLRRLRVPSAVHFRLHDFKFDDIHFEDDDTLKACLRMFLDLDFVERFHIDYEVLCRWLLSVKKNYRNVT--YHNWRHAFNVAQMMFAILTTTQWWKI--FGEIECLALIIGCLCHDLDHRGTNNSFQIKASSPLAQLYS-TSTMEHHHFDQCLMILNS-PGNQILANLSSDDYCRVIRVLEDAILSTDLAVYFKKRGPFLESVSQPTSY-------------------WVAEEPRALLRAMSMTVCDLSAITKPWEIEKRVADLVSSEFFEQGDME--KQELNITPIDIMNREKEDELPMMQVNFIDSICLPIYEAFATLS-----------------------DKLEPLVEGVRDNRGHWIDLADVVKTKTSQDQEPEEEQQQQNVISNGDCKAMSDDDVAASEAEVAVD----------------------------------------------------------SPSEKASVNGSNVANNSSNTNKKIAVASHPTSTQPSDDDNDVDADADDVDEQAAEENGHDAEVDEASCRSNSTCSSSTASSCLSTPPPTGEDDSTPVSPLKTLQAKLVAANLNALQRQTSNQAQTQKQRCKSCDHSRSGLQVRKTSSLRGAQELDLDSKTRNGTHAALCKSTPVINNHSHHHNHSHSHNHNHHHHHHHHSHHNHSQHGIGIGSASIGGSGLISLTTPLLAMDSDRIPKIVGKIGNLDGLPFANGIGGPQNGHGLPFGSYQHHHHHQHHHHLLARRHSETNSNGATAMAVEK-------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06776-1", "uniprot_id": "PDE2_YEAST", "id": "P06776-1", "name": "3',5'-cyclic-nucleotide phosphodiesterase 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTLFLIGIHEIEKSQTIVQN--------------------------------------------------------------------------------------------------------------EHYFDRVIELQDLDSLMVALYKDRVSPFPNVHN------------------FETGVSIVLYDPSKFQLSVRQLDVLFKRFFPS-------------------------------------------------------------------------------------------------------------------------FNISAIDHTREENLQRLECVE-----------------------------------------------RENSICRNRITRINHWMYHHHDDTPDGINKNSYGTVNGNSVPTQACEAN----------IYTLLLHLNDSKAQHLR------------------------------------------------------------------------------------------------------------------------------KASVPRLIRNIEFMS---------------------------FLSDPIEKISQEGSHYWNILSTWDFCALSLST----QELIWCGFTLIKKLSKDAKVLIADNKLLLLLFTLESSYHQVN-KFHNFRHAIDVMQATWRLCTYLLKDNP-----VQTLLLCMAAIGHDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHRELFQQLLSE--HWPQLLSISKKKFD----FISEAILATDMALHSQYEDRLMHENPMKQIT----------------------------LISLIIKAADISNVTRTLSISARWAYLITLEFNDCALLETFHKAHRPEQDCFGDSYKNVDSPKEDLESIQNILVNVTDPDDIIK------------------------DHPHIPNGQIFFINTFAEVFFNALSQKFSGLKFLSDNVKINKEYWMKHKKPQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * :** *. * : : .. ** * * .. * : : :* .* : : . ::.*:: : : .*:. : : *: * . : : : . ", "identical_positions": 16, "similar_positions": 35, "identity": "0.82%" }, { "cls_id": "homologset.agr.SGD:S000005888", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4G061-1", "uniprot_id": "EIF3B_RAT", "id": "Q4G061-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MQDAENVAAPEAAEERAEPARQQPVSESPPTD---EAAGSGGSEVGRTEDAEEDA---EARPEPEVRAKPAAQSEEETAASPAASPTPQSAQ-----EPSAPGKAEAGGEQAR-HPSAR-----AEEEGGSDGSAAEAEPRALENGEADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKIINDYYPE--EDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMT--ISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGD---RTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALWGGDKFKQIQRFSHQGVQLIDFSPCERYLVTFS------------PLMDTQDDPQAIIIWDILTGHKKRGFHCESS--AHWPIFKWSHDGKFFARMTLDTLSIYETPS-MGLLDKKSLKISGIKDFSWSPG-------------GNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQ----------GVVTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHG--------EAPRISVSFYHVKSNGK------IELIKMFDKQQANTIFWSPQGQFVVLAGLRSM---NGALAFVDTS---------------DCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQDQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRQYRKMAQELYMKQKNERLELRGGVDTDELDSNVDDWEEETIEFFVTEEVIPLGSQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JZQ9-1", "uniprot_id": "EIF3B_MOUSE", "id": "Q8JZQ9-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MQDAENVAVPEAAEERAEPARQQPASESPPTD---EAAGSGGSEVGQTEDAEEDA---EAGPEPEVRAKPAAQSEEETATSPAASPTPQSAERSPSQEPSAPGKAEAVGEQARGHPSAG-----AEEEGGSDGSAAEAEPRALENGEADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKIINDYYPE--EDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMT--ISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGD---RTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALWGGDKFKQIQRFSHQGVQLIDFSPCERYLVTFS------------PLMDTQDDPQAIIIWDILTGHKKRGFHCESS--AHWPIFKWSHDGKFFARMTLDTLSIYETPS-MGLLDKKSLKISGIKDFSWSPG-------------GNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQ----------GVVTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHG--------EAPRISVSFYHVKSNGK------IELIKMFDKQQANTIFWSPQGQFVVLAGLRSM---NGALAFVDTS---------------DCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQDQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRQYRKMAQELYMKQKNERLELRGGVDTDELDSNVDDWEEETIEFFVTEEVIPLGSQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55884-1", "uniprot_id": "EIF3B_HUMAN", "id": "P55884-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYPE--EDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMT--ISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGD---RTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALWGGEKFKQIQRFSHQGVQLIDFSPCERYLVTFS------------PLMDTQDDPQAIIIWDILTGHKKRGFHCESS--AHWPIFKWSHDGKFFARMTLDTLSIYETPS-MGLLDKKSLKISGIKDFSWSPG-------------GNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQ----------GVVTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHG--------EAPRISVSFYHVKNNGK------IELIKMFDKQQANTIFWSPQGQFVVLAGLRSM---NGALAFVDTS---------------DCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRGGVDTDELDSNVDDWEEETIEFFVTEEIIPLGNQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0E940-1", "uniprot_id": "EIF3B_DROME", "id": "Q0E940-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "----------------------------------------------------------------------MAKKK-------------------------------------------------SEEHSGTDANDSDYQ---------EEPNFDDPPGFVDNISDEDLLGDMLAQRPSEADGVESVVVVDNIPKVEPVRLEKLKLVINKLFSNYGEIVNVVYPVD-EEGKTKGYAFMEYKQARQAEEAVKKLNNHRLDKNHTFAVNLFTDFQKYEN--IPEKWEPPTVQTFKVQSDLYNFINDPDTYDQYCVAAETAPNCVQVGFWQNVLPEPFELETRERFTDTFVKWSPLGTYVVTFHKPGVAIWGGSSFQKIQKFPHPGTQFVEFSPCENYLVTYG------------PTPTG----QKIIIWDIRTGAEKRSFVADGM--SVLSMFRWSHDDKFVARMGENSIHIYETPS-FYLLDLKSIKIPGIRGFSWSPT-------------DNVIAYWVEEQNQIPARVTLMEIPKKREIRNKNLFHVADCKLHWQKSGDYLCVKVDRYSKLKKDKKDLDVKFLGMFYNFEIFHMREKEIPVDSVEIRELILAFAWEPVGNKFSIIHG--------ETNSSNVSFYEVNKGVK------PSLVKRLEKKSCTHLFWSPRGQFIVMANLT-----MGTFEFVDSTN--------------DYIITASPDHFRASEVEWDPTGRYVVTGVSSWKVKEDTGFNMYTFQGRIIKRTILKNFVQFLWRPRPPTLLSEEKQKEIKKNLKKYYAAFEQKDRLRLTRASKELLEKRSQLRETFMEYRNKRIAEWAEQKSRRIMLRGHVDTDNLET--DEVDEEIVEFLVKEEVTLLE---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06103-1", "uniprot_id": "EIF3B_YEAST", "id": "P06103-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "--------------------------------------------------------------MKNFLPRTLKNIYELYFN----------------------------------------------NISVHSIVSRNTQLKRSKIIQMTTETFEDIKLEDIPVDDIDFSDLEEQYKVTEEFNFDQYIVVNGAPVIPSAKVPVLKKALTSLFSKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRLDLKHRLFLYTMKDVERYNSDDFDTEFREPDMPTFVPSSSLKSWLMDDKVRDQFVLQDDVKTSVFWNSMFN---EEDSLVESRENWSTNYVRFSPKGTYLFSYHQQGVTAWGGPNFDRLRRFYHPDVRNSSVSPNEKYLVTFSTEPIIVEEDNEFSPFTKKNEGHQLCIWDIASGLLMATFPVIKSPYLKWPLVRWSYNDKYCARMVGDSLIVHDATKNFMPLEAKALKPSGIRDFSFAPEGVKLQPFRNGDEPSVLLAYWTPETNNSACTATIAEVPRGRVLKTVNLVQVSNVTLHWQNQAEFLCFNVERHTKSGK----------TQFSNLQICRLTERDIPVEKVELKDSVFEFGWEPHGNRFVTISVHEVADMNYAIPANTIRFYAPETKEKTDVIKRWSLVKEIPKTFANTVSWSPAGRFVVVGALVGPNMRRSDLQFYDMDYPGEKNINDNNDVSASLKDVAHPTYSAATNITWDPSGRYVTAWSSSLKHKVEHGYKIFNIAGNLVKEDIIAGFKNFAWRPRPASILSNAERKKVRKNLREWSAQFEEQDAMEADTAMRDLILHQRELLKQWTEYREKIGQEMEKSMNFKIFDVQPEDASDDFTTIEEIVEEVLEETKEKVE-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . : : .*.* :.: :: . : * ..:. :**:. * : . :: ** .: .:**: *:: * :* *****: *:* . .* . :*. .. :** :* : : :.*.::* . : :: * .* ..* :: : . **: : : .:: : :* * .:: .:*::** ***: ::*: *:: *** .*.::::* * ..: ..** *.****:. . : : **** :* * .:.:**::.*: *** ::: ::::.. : *: *::* .**:.**::* . ::*:*. * :: .. .*: ::* : :: **.:* : .****:..::**.:*:* .* : . *::* :: *:::**: **::: :: *.*** *.:* : .: ** :. * .*:* : * .. : *** *:*:*:. * . : * * . . : *::: ***:****.: * . * : .: ::.: *.:::. * :: *****.::**: : *:::*:*::: **::* : * ::*: :: : : : :**: :. . :: *:.: : :: ** :* : ", "identical_positions": 153, "similar_positions": 254, "identity": "17.17%" }, { "cls_id": "homologset.agr.SGD:S000005889", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18422-1", "uniprot_id": "PSA3_RAT", "id": "P18422-1", "name": "Proteasome subunit alpha type-3", "aln": "MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMK---EMTCRDVVKEVAKIIYIVHDEVKDKAFELELSWVG-ELTKGRHEIVPKDVREEAEKYAKESLK---EEDESDDDNM---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70435-1", "uniprot_id": "PSA3_MOUSE", "id": "O70435-1", "name": "Proteasome subunit alpha type-3", "aln": "MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSFMLGSYSANDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMK---EMTCRDVVKEVAKIIYIVHDEVKDKAFELELSWVG-ELTKGRHEIVPKDIREEAEKYAKESLK---EEDESDDDNM---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25788-1", "uniprot_id": "PSA3_HUMAN", "id": "P25788-1", "name": "Proteasome subunit alpha type-3", "aln": "MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMK---EMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVG-ELTNGRHEIVPKDIREEAEKYAKESLK---EEDESDDDNM---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V5C6-1", "uniprot_id": "PSA3_DROME", "id": "Q9V5C6-1", "name": "Proteasome subunit alpha type-3", "aln": "MSTIGTGYDLSASQFSPDGRVFQIDYASKAVEKSGTVIGIRGKDAVVLAVEKIITSKLYEPDAGGRIFTIEKNIGMAVAGLVADGNFVADIARQEAANYRQQFEQAIPLKHLCHRVAGYVHAYTLYSAVRPFGLSIILASWDEVEGPQLYKIEPSGSSFGYFACASGKAKQLAKTEMEKLKM----DMRTDELVESAGEIIYKVHDELKDKDFRFEMGLVG-RVTGGLHLINPSELTEKARKAGDAANK---DED-SDNETH---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21242-1", "uniprot_id": "PSA7_YEAST", "id": "P21242-1", "name": "Probable proteasome subunit alpha type-7", "aln": "MTSIGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKN-GAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAIDFAQKEINGDDDEDEDDSDNVMSSDDENAPVATNANATTDQEGDIHLE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::******** * ****** **::** ****:. * ***: :*.**:.***:: *** . :: :::::* . :**:.*.. :.: .*:**:.::. : **: :..*:. **:*:***.:***** * ::.. . *.:** ::*** :** ..* **.:* **:*:*** : : *:...:*** .*:: *:* *.:*:. . * * * : :: ::* . .. : :** .*.:. ", "identical_positions": 93, "similar_positions": 94, "identity": "32.18%" }, { "cls_id": "homologset.agr.SGD:S000005894", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XFX0-1", "uniprot_id": "TAGL2_RAT", "id": "Q5XFX0-1", "name": "Transgelin-2", "aln": "----MANRGPSYGLSREVQQKIEKQYDPDLEQILIQWITTQCRKGVSQPQPGRENFQNWLKDGTVLCELINSLYPEGQAPVKKIQ--ASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPR---NFSDNQLQEGKNVIGLQMGTNRGASQA-GMTGYGMPRQIL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P37802-1", "uniprot_id": "TAGL2_HUMAN", "id": "P37802-1", "name": "Transgelin-2", "aln": "----MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVLCELINALYPEGQAPVKKIQ--ASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPR---NFSDNQLQEGKNVIGLQMGTNRGASQA-GMTGYGMPRQIL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WVA4-1", "uniprot_id": "TAGL2_MOUSE", "id": "Q9WVA4-1", "name": "Transgelin-2", "aln": "----MANRGPSYGLSREVQQKIEKQYDADLEQILIQWITTQCREDVGQPQPGRENFQKWLKDGTVLCKLINSLYPEGQAPVKKIQ--ASSMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPR---NFSDNQLQEGKNVIGLQMGTNRGASQA-GMTGYGMPRQIL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R1Q8-1", "uniprot_id": "TAGL3_MOUSE", "id": "Q9R1Q8-1", "name": "Transgelin-3", "aln": "----MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKIS--ESKMAFKQMEQISQFLKAAEVYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRR---GFSEEQLRQGQNVIGLQMGSNKGASQA-GMTGYGMPRQIM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UI15-1", "uniprot_id": "TAGL3_HUMAN", "id": "Q9UI15-1", "name": "Transgelin-3", "aln": "----MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKIS--ESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRR---GFSEEQLRQGQNVIGLQMGSNKGASQA-GMTGYGMPRQIM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P37805-1", "uniprot_id": "TAGL3_RAT", "id": "P37805-1", "name": "Transgelin-3", "aln": "----MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRTHFQKWLMDGTVLCKLINSLYPPGQEPIPKIS--ESKMAFKQMEQISQFLKAAEVYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRR---GFSEEQLRQGQNVIGLQMGSNKGASQA-GMTGYGMPRQIM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P37804-1", "uniprot_id": "TAGL_MOUSE", "id": "P37804-1", "name": "Transgelin", "aln": "----MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIVVQCGPDVGRPDRGRLGFQVWLKNGVILSKLVNSLYPEGSKPVKVPEN-PPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLYEGKDMAAVQRTLMALGSLAVTKNDGNYRGDPNWFMKKAQEHKR---DFTDSQLQEGKHVIGLQMGSNRGASQA-GMTGYGRPRQIIS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31232-1", "uniprot_id": "TAGL_RAT", "id": "P31232-1", "name": "Transgelin", "aln": "----MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIVMQCGPDVGRPDRGRLGFQVWLKNGVILSKLVNSLYPEGSKPVKVPEN-PPSMVFKQMEQVAQFLKAAEDYGVTKTDMFQTVDLFEGKDMAAVQRTVMALGSLAVTKNDGHYRGDPNWFMKKAQEHKR---EFTDSQLQEGKHVIGLQMGSNRGASQA-GMTGYGRPRQIIS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01995-1", "uniprot_id": "TAGL_HUMAN", "id": "Q01995-1", "name": "Transgelin", "aln": "----MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGVILSKLVNSLYPDGSKPVKVPEN-PPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEGKDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKR---EFTESQLQEGKHVIGLQMGSNRGASQA-GMTGYGRPRQIIS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08091-1", "uniprot_id": "CNN1_MOUSE", "id": "Q08091-1", "name": "Calponin-1", "aln": "MSSAHFNRGPAYGLSAEVKNKLAQKYDHQREQELREWIEGVTGRRIG------NNFMDGLKDGIILCEFINKLQP-GS--VKKVN--ESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQVQSTLLALASMAKTKG-----NKVNVGVKYAEKQER---RFEPEKLREGRNIIGLQMGTNKFASQQ-GMTAYGTRRHLYDPKLGTDQPLDQATISLQMGTNKGASQAG---------------MTAP----------GTKRQIFEPGLG----MEHCDTLNVSLQ------MGSNKGASQ--------------------RGMTVYGLP-----------------------RQVYDPKYCLNPEYPELSEPTHN---------------HHPHNYYNSA-----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08290-1", "uniprot_id": "CNN1_RAT", "id": "Q08290-1", "name": "Calponin-1", "aln": "MSSAHFNRGPAYGLSAEVKNKLAQKYDHQREQELREWIEGVTGRRIG------SNFMDGLKDGIILCEFINKLQP-GS--VKKVN--ESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQVQSTLLALASMAKTKG-----NKVNVGVKYAEKQER---RFEPEKLREGRNIIGLQMGTNKFASQQ-GMTAYGTRRHLYDPKLGTDQPLDQATISLQMGTNKGASQAG---------------MTAP----------GTKRQIFEPGLG----MEHCDTLNVSLQ------MGSNKGASQ--------------------RGMTVYGLP-----------------------RQVYDPKYCLTPEYPELDEPTHN---------------HHPHNYYNSA-----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51911-1", "uniprot_id": "CNN1_HUMAN", "id": "P51911-1", "name": "Calponin-1", "aln": "MSSAHFNRGPAYGLSAEVKNKLAQKYDHQREQELREWIEGVTGRRIG------NNFMDGLKDGIILCEFINKLQP-GS--VKKIN--ESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQVQSTLLALASMAKTKG-----NKVNVGVKYAEKQER---KFEPGKLREGRNIIGLQMGTNKFASQQ-GMTAYGTRRHLYDPKLGTDQPLDQATISLQMGTNKGASQAG---------------MTAP----------GTKRQIFEPGLG----MEHCDTLNVSLQ------MGSNKGASQ--------------------RGMTVYGLP-----------------------RQVYDPKYCLTPEYPELGEPAHN---------------HHAHNYYNSA-----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DAW9-1", "uniprot_id": "CNN3_MOUSE", "id": "Q9DAW9-1", "name": "Calponin-3", "aln": "--MTHFNKGPSYGLSAEVKNKIASKYDQQAEEDLRNWIEEVTGLGIG------TNFQLGLKDGIILCELINKLQP-GS--VKKVN--ESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTLVALAGLAKTKGF---HTTIDIGVKYAEKQTR---RFDEGKLKAGQSVIGLQMGTNKCASQA-GMTAYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAG---------------MLAP----------GTRRDIYDQKLT----LQPVDNSTISLQ------MGTNKVASQ--------------------KGMSVYGLG-----------------------RQVYDPKYCAAPTEPVIHNGSQGTGTNGSEISDSDYQAEYPDEYHGEYPDDYPREYQYGDDQGIDY-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P37397-1", "uniprot_id": "CNN3_RAT", "id": "P37397-1", "name": "Calponin-3", "aln": "--MTHFNKGPSYGLSAEVKNKIASKYDQQAEEDLRNWIEEVTGMGIG------TNFQLGLKDGIILCELINKLQP-GS--VKKVN--ESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTLVALAGLAKTKGF---HTTIDIGVKYAEKQTR---RFDEGKLKAGQSVIGLQMGTNKCASQA-GMTAYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAG---------------MSAP----------GTRRDIYDQKLT----LQPVDNSTISLQ------MGTNKVASQ--------------------KGMSVYGLG-----------------------RQVYDPKYCAAPTEPVIHNGSQGTGTNGSEISDSDYQAEYPDEYHGEYPDEYPREYQYGDDQGIDY-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15417-1", "uniprot_id": "CNN3_HUMAN", "id": "Q15417-1", "name": "Calponin-3", "aln": "--MTHFNKGPSYGLSAEVKNKIASKYDHQAEEDLRNWIEEVTGMSIG------PNFQLGLKDGIILCELINKLQP-GS--VKKVN--ESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTLVALAGLAKTKGF---HTTIDIGVKYAEKQTR---RFDEGKLKAGQSVIGLQMGTNKCASQA-GMTAYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAG---------------MLAP----------GTRRDIYDQKLT----LQPVDNSTISLQ------MGTNKVASQ--------------------KGMSVYGLG-----------------------RQVYDPKYCAAPTEPVIHNGSQGTGTNGSEISDSDYQAEYPDEYHGEYQDDYPRDYQYSD-QGIDY-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08093-1", "uniprot_id": "CNN2_MOUSE", "id": "Q08093-1", "name": "Calponin-2", "aln": "MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRSWIEGLTGLSIG------PDFQKGLKDGVILCTLMNKLQP-GS--VPKIN--RSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQVQVSLLALAGKAKTKGL---QSGVDIGVKYSEKQER---NFDDATMKAGQCVIGLQMGTNKCASQS-GMTAYGTRRHLYDPKNHILPPMDHCTISLQMGTNKCASQVG---------------MTAP----------GTRRHIYDTKLG----TDKCDNSSMSLQ------MGYTQGAN---------------------QSGQVFGLG-----------------------RQIYDPKYCPQGSAADGAPAGDG----------QGEAPEYLAYCQEEAGY---------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99439-1", "uniprot_id": "CNN2_HUMAN", "id": "Q99439-1", "name": "Calponin-2", "aln": "MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIG------PDFQKGLKDGTILCTLMNKLQP-GS--VPKIN--RSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQVQVSLLALAGKAKTKGL---QSGVDIGVKYSEKQER---NFDDATMKAGQCVIGLQMGTNKCASQS-GMTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVG---------------MTAP----------GTRRHIYDTKLG----TDKCDNSSMSLQ------MGYTQGAN---------------------QSGQVFGLG-----------------------RQIYDPKYCPQGTVADGAPSGTGDCP------DPGEVPEYPPYYQEEAGY---------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0M5V0-1", "uniprot_id": "A0ABK0M5V0_RAT", "id": "A0ABK0M5V0-1", "name": "Calponin", "aln": "MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRSWIEGLTGLSIG------PDFQKGLKDGVILCTLMNKLQP-GS--VPKIN--RSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQVQVSLLALAGKAKTKGL---QSGVDIGVKYSEKQER---NFDDATMKAGQCVIGLQMGTNKCASQS-GMTAYGTRRHLYDPKNHILPPMDHCTISLQMGTNKCASQHQGPGGTSMTPSWAPTSATTPPCPCRWATHRAPTRAARSSDWGGRYMTPSIAHRALQLTGLLPGVMAKARPLNTCPTARRKPATEHPGVPAPRLASAALCGFGGFHCVVLCFETGHLFVAISGLELMQSFCLSFLRTGVTAPSSPTMPRFLPR---TDPPGREHGFPWWDSEAVHFLVGGAVGGAGPKSFRFFPLFYMVFVVCEPRKLQAVSFFFLFFFFFFFGAGD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VZI1-1", "uniprot_id": "Q9VZI1_DROME", "id": "Q9VZI1-1", "name": "Transgelin", "aln": "---MASNRAAKSGFAAEAQRKINSKYSEELAQESLEWIKAVTEEPINTSG-DTDNFFEVLKDGVILCKLANALQP-GS--IKKIN--ESKMAFKCMENISAFLACAKNFGVPTQETFQSVDLWERQNLNSVVICLQSLGRKASNFN------KPSIGPKEADKNVR---NFSDEQLRAGANVISLQYGSNKGATQS-GIN-FGNTRHM---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14318-1", "uniprot_id": "MP20_DROME", "id": "P14318-1", "name": "Muscle-specific protein 20", "aln": "-----------MSLERAVRAKIASKRNPEMDKEAQEWIEAIIAEKFP----AGQSYEDVLKDGQVLCKLINVLSP-NA--VPKVN--SSGGQFKFMENINNFQKALKEYGVPDIDVFQTVDLYEKKDIANVTNTIFALGRATYKHAD---FKGPFLGPKPADECKR---DFTEEQLKAGQTIVGLQAGSNKGATQA-GQN-LGAGRKILLGK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7J0-1", "uniprot_id": "Q9I7J0_DROME", "id": "Q9I7J0-1", "name": "Calponin-homology (CH) domain-containing protein", "aln": "----------------------MAPRNKEQEQEVLNWVFAVIGEKVP----SGQ-YEDILKDGIWLCKLANKLAP-GS--VKKIQ--ERGTNFQLMENIQRFQAAVKKYGVPEEEIFQTADLFERRNIPQVTLSLYALGRITQKHPE---YTGPTLGPKMADKNER---SFTEEQLRAHEGELNLQMGFNKGASQA-GHGGMGNTRHM---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08873-1", "uniprot_id": "SCP1_YEAST", "id": "Q08873-1", "name": "Transgelin", "aln": "--MSYDKKADVTSLDEDLRQLRESKFSPEAIQNIKIWVYKSVLKEIAPP----GDLLECLKDGTVLCKLANILYEADTGEANHISWKSSKMPFVQMDQISQFLSFSRKYGVPEDELFQTIDLFEKKDPAIVFQTLKSLSRYANKKHT---DRFPVLGPQLSTKKPRPPVKSKPKHLQDGTGWSTFEYGYMKGASQATEGVVLGQRRDIV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *: . * :* *. : * * . . : :::: * :*: : *:: **:* : * : *. : : : : * :: :: * : *:* * *.: ", "identical_positions": 20, "similar_positions": 35, "identity": "4.32%" }, { "cls_id": "homologset.agr.SGD:S000005895", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZC52-1", "uniprot_id": "D3ZC52_RAT", "id": "D3ZC52-1", "name": "Cell cycle checkpoint protein RAD1", "aln": "MPLLTQYNEDEYEQYCLVASLDNVRNLSTVLKAIHFKEHATCFATKNGIKVTVENAKCVQANAFIQADVFQEFIIQEE---SVTFRINLTILLDCLSIFGSSPTPGTLTALRMCYQGYGHPLMLFLE---EGGVVTVCKITTQEPED-TLDFDFCSTN-VMNKIILQSEGLREAFSELDMT----GDVLQITVSPDKPYFRLSTFGNAGNSH-LDYPKDS---DLVEAFHCNKTQINR-------YKLSLLKPSTKALALSCKVSIRTDNRGFLSLQYMIRNEDGQI-------------------------CFVEYYCCPDEEVPES----------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QWZ1-1", "uniprot_id": "RAD1_MOUSE", "id": "Q9QWZ1-1", "name": "Cell cycle checkpoint protein RAD1", "aln": "MPLLTQYNEEEYEQYCLVASLDNVRNLSTVLKAIHFREHATCFATKNGIKVTVENAKCVQANAFIQADVFQEFVIQEE---SVTFRINLTILLDCLSIFGSSPTPGTLTALRMCYQGYGHPLMLFLE---EGGVVTVCKITTQEPEE-TLDFDFCSTN-VMNKIILQSEGLREAFSELDMT----GDVLQITVSPDKPYFRLSTFGNAGNSH-LDYPKDS---DLVEAFHCDKTQVNR-------YKLSLLKPSTKALALSCKVSIRTDNRGFLSLQYMIRNEDGQI-------------------------CFVEYYCCPDEEVPES----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60671-1", "uniprot_id": "RAD1_HUMAN", "id": "O60671-1", "name": "Cell cycle checkpoint protein RAD1", "aln": "MPLLTQQIQDEDDQYSLVASLDNVRNLSTILKAIHFREHATCFATKNGIKVTVENAKCVQANAFIQAGIFQEFKVQEE---SVTFRINLTVLLDCLSIFGSSPMPGTLTALRMCYQGYGYPLMLFLE---EGGVVTVCKINTQEPEE-TLDFDFCSTN-VINKIILQSEGLREAFSELDMT----SEVLQITMSPDKPYFRLSTFGNAGSSH-LDYPKDS---DLMEAFHCNQTQVNR-------YKISLLKPSTKALVLSCKVSIRTDNRGFLSLQYMIRNEDGQI-------------------------CFVEYYCCPDEEVPESES--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQD4-1", "uniprot_id": "RAD1_DROME", "id": "Q9VQD4-1", "name": "DNA repair protein Rad1", "aln": "---MTDVEPSPYGDCKFVARVEHIKTFIQAIKSICFNDYGMVQVSEDGLRITVEQGKSIQATLFMPPGAFMEFRVQD----FQCFGVKMNVLSECLSLFGSADCS-----LRMMYRDKGDPLKIILYPHDDDDVSTECAIKTMDCDE-PIDYDQNLKDPDLNVIFVRGPNLSKVFNELEKS----AEEFEFVTSPNRPHFKITTVGIMQAVFSVEVAKTS---PMMMMFNCKQTVVAR-------YKSQQIRMTNKAMQSATKVAIKTNSVGLLELHLVMQGDSQEE-------------------------IFIQFFIIPLLNTD------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48581-1", "uniprot_id": "RAD17_YEAST", "id": "P48581-1", "name": "DNA damage checkpoint control protein RAD17", "aln": "---MRINSELANKFSASTVHLEHITTALSCLTPFGSKDDVLIFIDADGLSFVRENNHVIKIQLLLSRELFMSYSYRNETEDHMKLCVKINHILDSVSVMNRNSDD--IVECTLSYDGHGSPFVLIFEDSFISERVEYSTYLIKDFDTNGLELDRERIS---FEAIIKGEALHSALKDLKEIGCKECYVYAKTEANDENVFALISKSQLGFSK-IKLPSNRSILEKLQVFDGDSTTVIDGFAVIGFFDFTSFDKIRKSTKIASKVLFRMDVHGVLSVNILSQTDDVIITDTTRPSNNRPGSIRQLQLPKDYPGIVIEVCMLEKESIDEAAQTEIELLMETNELGNRNSFKKSTIRKRYGTDKGNETSNDNLLQLNGKKIKLPSEEENNKNRESEDEENHCKYPTKDIPIFF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. :::: . :..: .: :*: .. *: : :: :: * .: :: : :::. : :.:*::. : * . * *: ::: . . : : :: * . :::. * ..:.:*. . : :. * : : . :. .. : *. ..* : :. : *: : ** :: : *.*.:: : : :. .:: . ", "identical_positions": 18, "similar_positions": 99, "identity": "4.39%" }, { "cls_id": "homologset.agr.SGD:S000005896", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P25398-1", "uniprot_id": "RS12_HUMAN", "id": "P25398-1", "name": "Small ribosomal subunit protein eS12", "aln": "MAEEGIAAG----------GVMDVNTALQEVLKTALIHDGLARGIREAAKALDK-----RQAHLCVLASNCDEPMYVKLVEALCA--EHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFKCKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZHB3-1", "uniprot_id": "D3ZHB3_RAT", "id": "D3ZHB3-1", "name": "40S ribosomal protein S12", "aln": "MAEEGIAAG----------GVMDVNTALQEVLKTALIHNGLARGIREAAKALDKKHRKRRQAHLCVLASNCDEPMYVKLVEALCA--EHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFKCKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63323-1", "uniprot_id": "RS12_MOUSE", "id": "P63323-1", "name": "Small ribosomal subunit protein eS12", "aln": "MAEEGIAAG----------GVMDVNTALQEVLKTALIHDGLARGIREAAKALDK-----RQAHLCVLASNCDEPMYVKLVEALCA--EHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFKCKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63324-1", "uniprot_id": "RS12_RAT", "id": "P63324-1", "name": "Small ribosomal subunit protein eS12", "aln": "MAEEGIAAG----------GVMDVNTALQEVLKTALIHDGLARGIREAAKALDK-----RQAHLCVLASNCDEPMYVKLVEALLA--EHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFKCKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6GKR8-1", "uniprot_id": "A0A8I6GKR8_RAT", "id": "A0A8I6GKR8-1", "name": "40S ribosomal protein S12", "aln": "MAEEGIAAG----------GVMDVNTALQEVLKTALIHDGLVRGIREAAKALDK-----RQAHLCVLASNCDEPMYVKLVEALCA--EHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFKCKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LUA5-1", "uniprot_id": "A0ABK0LUA5_RAT", "id": "A0ABK0LUA5-1", "name": "40S ribosomal protein S12", "aln": "MAEEGIAAG----------GVMDVNTALQEVLKTALIHDGLARGIREAAKALDK-----CQAHLCVLASNCDEPMYVKLVEALCA--EHQINLIKVDDNKKLGEWVGLCKIDREGKPQKVVGCSCVVVKDYGKESQAKDVIEEYFKCKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZG05-1", "uniprot_id": "D3ZG05_RAT", "id": "D3ZG05-1", "name": "40S ribosomal protein S12", "aln": "MAEEGIAAG----------GVMDINTALQEVPKTALIHDGLARGICEAAKALDK-----RQGHLCVLASNYDEPMYVKLVAALCA--EHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFEYKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZEB8-1", "uniprot_id": "D3ZEB8_RAT", "id": "D3ZEB8-1", "name": "40S ribosomal protein S12", "aln": "MAEEGIAAG----------GVMDANTALQEVLKTALIHDGLARGIWEAAKALDK-----RQAHLCVLASNYDEPMYVKLVEALCA--EHQVNLIKVDDNKKLGEWVGLCKIDRKGKPRKVVGCSCVVVKDYGKESQAKDVIKEYFKCKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A9C8-1", "uniprot_id": "D4A9C8_RAT", "id": "D4A9C8-1", "name": "40S ribosomal protein S12", "aln": "MAEESIAVG----------GVMDINTALQGMLKTALIHDSLARDIREAAKAFDK-----RQAHVYVLASDCDEPMCVKLVYALCA--EHQINLIKADDNKKLGEWGGLCKIDREGKPQKVVVCSCVVVQDYGKESQAKDIIKEYFKCKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4AAJ3-1", "uniprot_id": "D4AAJ3_RAT", "id": "D4AAJ3-1", "name": "40S ribosomal protein S12", "aln": "MAEGDIAAG----------GVIDINTALQEVLKTAFIHDALACGIREAAKALDK-----CQAHLCVLASNCDEPMYVKLVEALCA--EHQINLMKVDDNKKLGEWVGPCKIDLEGKPLKVVGCSCIVVKDYGKESQDKDVIKEYFKCKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0M3X9-1", "uniprot_id": "A0ABK0M3X9_RAT", "id": "A0ABK0M3X9-1", "name": "40S ribosomal protein S12", "aln": "---------------------MDSNTALQEVLKTAIIHDGLARGIRKAAKALDK-----RQAHLCVLASDCDEPMYVKLVEALCA--EHQINLIKVDDNKKLGEWVGLCKIHREEKPRKVVGCSCVVVKDYGKESQAKDVIEEYFKCKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LJM9-1", "uniprot_id": "A0ABK0LJM9_RAT", "id": "A0ABK0LJM9-1", "name": "40S ribosomal protein S12", "aln": "MAKEDTAAG----------VIMDVNTALQEVLKTALVHDGLARGIHEAAKALGK-----RQAHLCVLAANCDKPMYIKLVETLCA--EHQINLIKVDDNKKLGEWVGLCKIDRKGKPRKVIGCSCVVVKDYGQESQAKDVIEEYFKCKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P80455-1", "uniprot_id": "RS12_DROME", "id": "P80455-1", "name": "Small ribosomal subunit protein eS12", "aln": "MADVDVDVPSAAP---VLDGAMDINTALQEVLKKSLIADGLVHGIHQACKALDK-----RQAVLCILAESFDEPNYKKLVTALCN--EHQIPLIRVDSHKKLGEWSGLCKIDKEGKPRKVCGCSVVVIKDFGEETPALDVVKDHLRQNS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48589-1", "uniprot_id": "RS12_YEAST", "id": "P48589-1", "name": "Small ribosomal subunit protein eS12", "aln": "MSDVEEVVEVQEETVVEQTAEVTIEDALKVVLRTALVHDGLARGLRESTKALTR-----GEALLVVLVSSVTEANIIKLVEGLANDPENKVPLIKVADAKQLGEWAGLGKIDREGNARKVVGASVVVVKNWGAETDELSMIMEHFSQQ-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : **: : :.::: :.*. .: :: **: : :. : :*. . :. *** * *::: *::. . *:**** * **. : :. ** .* :*::::* *: .:: ::: : ", "identical_positions": 26, "similar_positions": 52, "identity": "17.45%" }, { "cls_id": "homologset.agr.SGD:S000005897", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P26374-1", "uniprot_id": "RAE2_HUMAN", "id": "P26374-1", "name": "Rab proteins geranylgeranyltransferase component A 2", "aln": "--------------------------------------MADNLPTEFDVVIIGTGLPESILAAACSRSGQRVLHIDSRSYYGGNWASFSFSGLLSWLKEYQQNNDIGEESTVVWQDLIHETEEAITLRKKDETIQHTEAFCYASQDMEDNVEEIGALQKNPSLGVSNTFTEVLDSA-LPEESQLSYFNSDEMPAKHTQKSDTEISLEVTDVEESVEKEKYCGDKTCMHTVSDKDGDKDESKSTVEDKADEPIRNRITYSQIVKEGRRFNIDLVSKLLYSQGLLIDLLIKSDVSRYVEFKNVTRILAFREGKVEQVPCSRADVFNSKELTMVEKRMLMKFLTFCLEY--EQHPDEYQAFRQCSFSEYL-KTKKLTPNLQHFVLHSIAMTSESSCTTIDGLNATKNFLQCLGRFGNTPFLFPLYG-QGEIPQGFCRMCAVFGGIYCLRHKVQCFVVDKESGRCKAIIDHFGQRINAKYFIVEDSYLSEETCSNVQYKQISRAVLITDQSILKTDLDQQTS--ILIVPPAEPGACA--VRVTELCSSTMTCMKDTYLVHLTCSSS-KTAREDLESVVKKLFTPYTETEINEEE------------------------------LTKPRLLWALYFNMRDSS---------------GISRSSYNGLPSN-VYVCSGPDCGLGNEHAVKQAETLFQEIFPTEEFCPPPPNPEDIIFDGDDKQPEAPGTNNVVMAKLESSEESKNLESPEKHLQN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AAJ7-1", "uniprot_id": "A0A8I6AAJ7_RAT", "id": "A0A8I6AAJ7-1", "name": "Rab proteins geranylgeranyltransferase component A", "aln": "--------------------------------------MADKLPTEFDVVIIGTGLPESILAAACSRSGQRVLHVDSRSYYGGNWASFSFTGLLSWLKDYQQNHDSEGDVTGTWQDLIDETEEAIALCKKDETIQHTEVFCYASQDVEDSMQETDPLQKSPSPEASATPADSLDTASLPKERHSEDCTSYEAPSRRTEGSDGAVSLSSADAQDSLEKEKFCGDETGMHTVSD--GEEGEHKLAAEDNVGQPKRNTITYSQMVKESRTFNIDLVSKLLYSQGSLIDLLIKSNVSRYAEFKNVTRILAFREGKVEQVPCSRADVFNSKELTMVEKRMLMKFLTFCLDY--EQHSDEYQDFKQCSFSDYL-KTKKLTPNLQHFILHSIAMSSDSSCTTLDGLQATKNFLRCLGRFGNTPFIFPLYG-QGEIPQCFCRMCAVFGGVYCLRHKVQCLVVDRDSGRCKGIIDGFGQRISANYFIVEDSYLSKEMCSNIQYKQISRAVLITDQSILKTDSDQQIS--ILVVPPLEPGTAS--VRVMELCSSTMTCMKDSYLVHLTCFSS-KTAREDLEPVVKQLFIPFAEAEADKEE------------------------------LRKPRLLWALYFNMRDSS---------------GVSRSSYCSLPSN-VYICSGPDCGLGNEHAVKQAETLFQEIFPSEEFCPPPPNPEDIIFEAEG----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24386-1", "uniprot_id": "RAE1_HUMAN", "id": "P24386-1", "name": "Rab proteins geranylgeranyltransferase component A 1", "aln": "--------------------------------------MADTLPSEFDVIVIGTGLPESIIAAACSRSGRRVLHVDSRSYYGGNWASFSFSGLLSWLKEYQENSDIVSD-SPVWQDQILENEEAIALSRKDKTIQHVEVFCYASQDLHEDVEEAGALQKNHALVTSANSTEAADSAFLPTEDESLSTMSCEMLTEQTPSSDPENALEVNGAEVTGEKENHCDDKTCVPSTSA--EDMSENVPIAEDTTEQPKKNRITYSQIIKEGRRFNIDLVSKLLYSRGLLIDLLIKSNVSRYAEFKNITRILAFREGRVEQVPCSRADVFNSKQLTMVEKRMLMKFLTFCMEY--EKYPDEYKGYEEITFYEYL-KTQKLTPNLQYIVMHSIAMTSETASSTIDGLKATKNFLHCLGRYGNTPFLFPLYG-QGELPQCFCRMCAVFGGIYCLRHSVQCLVVDKESRKCKAIIDQFGQRIISEHFLVEDSYFPENMCSRVQYRQISRAVLITDRSVLKTDSDQQIS--ILTVPAEEPGTFA--VRVIELCSSTMTCMKGTYLVHLTCTSS-KTAREDLESVVQKLFVPYTEMEIENEQ------------------------------VEKPRILWALYFNMRDSS---------------DISRSCYNDLPSN-VYVCSGPDCGLGNDNAVKQAETLFQEICPNEDFCPPPPNPEDIILDGDSLQPEASESSAIPEANSETFKESTNLGNLEESSE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V8W3-1", "uniprot_id": "RABEP_DROME", "id": "Q9V8W3-1", "name": "Rab proteins geranylgeranyltransferase component A", "aln": "--------------------------------------MLDDLPEQFDLVVIGTGFTESCIAAAGSRIGKSVLHLDSNEYYGDVWSSFSMDALCARLDQEVEPHSALRNARYTWHSMEKESETDAQSWNRD--------------------------------------------------------------------------------------------------------------------------------SVLAKSRRFSLDLCPRILYAAGELVQLLIKSNICRYAEFRAVDHVCMRHNGEIVSVPCSRSDVFNTKTLTIVEKRLLMKFLTACNDYGEDKCNEDSLEFRGRTFLEYL-QAQRVTEKISSCVMQAIAMCG-PSTSFEEGMQRTQRFLGSLGRYGNTPFLFPMYG-CGELPQCFCRLCAVYGGIYCLKRAVDDIALDSNSN--EFLLSSAGKTLRAKNVVSAPGYTPVSKGIELKP-HISRGLFISSSPLGNEELNKGGGGVNLLRLLDNEGGRE--AFLIQLSHYTGACPEGLYIFHLTTPALSEDPASDLAIFTSQLFD-----------------------------------------QSDAQIIFSSYFTIAAQS---------------SKS-----PAAEH-IYYTDPPTYELDYDAAIANARDIFGKMFPDADFLPRAPDPEEIVVDGED--PSALNEHTLPEDLRAQLHDMQQATQEMDIQE-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32864-1", "uniprot_id": "RAEP_YEAST", "id": "P32864-1", "name": "Rab proteins geranylgeranyltransferase component A", "aln": "MLSPERRPSMAERRPSFFSFTQNPSPLVVPHLAGIEDPLPATTPDKVDVLIAGTGMVESVLAAALAWQGSNVLHIDKNDYYGDTSATLTVDQIKRWVNEVNEGSVSCYKNAKLYVSTLIGSG-------------------------------------------------------------------------------------------------------------------------------------------KYSSRDFGIDLSPKILFAKSDLLSILIKSRVHQYLEFQSLSNFHTYENDCFEKLTNTKQEIFTDQNLPLMTKRNLMKFIKFVLNW--EAQTEIWQPYAERTMSDFLGEKFKLEKPQVFELIFSIGLCYDLNVKVPEALQRIRRYLTSFDVYGPFPALCSKYGGPGELSQGFCRSAAVGGATYKLNEKLVSFNP---TTKVATFQDGSKVEVSEKVIISPTQAPKDSKHVPQQQYQVHRLTCIVENPCTEWFNEGESAAMVVFPPGSLKSGNKEVVQAFILGAGSEICPEGTIVWYLSTTEQGPRAEMDIDAALEAMEMALLRESSSGLENDEEIVQLTGNGHTIVNSVKLGQSFKEYVPRERLQFLFKLYYTQYTSTPPFGVVNSSFFDVNQDLEKKYIPGASDNGVIYTTMPSAEISYDEVVTAAKVLYEKIVGSDDDFFDLDFEDEDEIQASGVANAEQFENAIDDDDDVNMEGSGEFVGEMEI---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :.*::: ***: ** :*** : * ***:*...***. ::::. : :.: : . : . . ..* *.:** .::*:: . *:.:**** : :* **: : .. .:. . .:. :: ::*. : *.:: ** ****:. :: : : : :: ::* : :: :: :*.: . :.:: :.:* .:. :* * : . ** **:.* *** .** *. * *.. : : : : . : : .: . : :: * * . . : : . : . . * : * :. : :*: . *: . : :::: *:. .: . . ..: : * :. : .: *. :: :: : :: .:... ", "identical_positions": 66, "similar_positions": 165, "identity": "8.8%" }, { "cls_id": "homologset.agr.SGD:S000005901", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CZS1-1", "uniprot_id": "AL1B1_MOUSE", "id": "Q9CZS1-1", "name": "Aldehyde dehydrogenase family 1 member B1, mitochondrial", "aln": "-MLTARLLLPRLLCLQGR-TTSYSTAAALPNPIPNPE----ICYNKLFINNEWHDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDLAVKAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYVLDLDEVIKVYRYFAGWADKWHGKTIPMDGEHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGHLIQKAAGESNLKRVTLELGGKSPSIVLADADMEHAVDQCHEALFFNMGQCCCAGSRTFVEESIYREFLERTVEKAKQRKVGNPFELDTQQGPQVDKEQFERILGYIRLGQKEGAKLLCGGER-LGERGFFIKPTVFGDVQDGMRIAKEEIFGPVQPLFKFKKIEEVIQRANNTRYGLAAAVFTRDLDKAIYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLRAYTEVKTVTIKVPEKNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66HF8-1", "uniprot_id": "AL1B1_RAT", "id": "Q66HF8-1", "name": "Aldehyde dehydrogenase family 1 member B1, mitochondrial", "aln": "-MLNARFLVPRLLCLQGR-TTSYSTAAALPNPIPNPE----IRYNQLFINNEWHDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDLAVRAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYVLDLDEVIKVYRYLAGWADKWHGKTIPMDGEHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMDHAVDQCHEALFFNMGQCCCAGSRTFVEESIYHEFLERTVEKAKKRKVGNPFELDTQQGPQVDKEQFEKILGYIRLGQKEGAKLLCGGER-FGERGFFIKPTVFGNVQDDMRIAREEIFGPVQPLFKFKKIEEVIQRANNTRYGLAAAVFTRDLDKALYFSQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIKVSEKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30837-1", "uniprot_id": "AL1B1_HUMAN", "id": "P30837-1", "name": "Aldehyde dehydrogenase family 1 member B1, mitochondrial", "aln": "-ML--RFLAPRLLSLQGR-TARYSSAAALPSPILNPD----IPYNQLFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDRAVKAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYALDLDEVIKVYRYFAGWADKWHGKTIPMDGQHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHVDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFLERTVEKAKQRKVGNPFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGER-FGERGFFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKKIEEVVERANNTRYGLAAAVFTRDLDKAMYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIKVPQKNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47738-1", "uniprot_id": "ALDH2_MOUSE", "id": "P47738-1", "name": "Aldehyde dehydrogenase, mitochondrial", "aln": "-MLRAALTTVRRGPRLSR-LLSAAATSAVPAPNHQPE----VFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGNKEDVDKAVKAARAAFQLGSPWRRMDASDRGRLLYRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEGVDKVAFTGSTEVGHLIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQENVYDEFVERSVARAKSRVVGNPFDSRTEQGPQVDETQFKKILGYIKSGQQEGAKLLCGGGA-AADRGYFIQPTVFGDVKDGMTIAKEEIFGPVMQILKFKTIEEVVGRANDSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11884-1", "uniprot_id": "ALDH2_RAT", "id": "P11884-1", "name": "Aldehyde dehydrogenase, mitochondrial", "aln": "-MLRAALSTARRGPRLSR-LLSAAATSAVPAPNQQPE----VFCNQIFINNEWHDAVSKKTFPTVNPSTGEVICQVAEGNKEDVDKAVKAAQAAFQLGSPWRRMDASDRGRLLYRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEVGHLIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDVYDEFVERSVARAKSRVVGNPFDSRTEQGPQVDETQFKKILGYIKSGQQEGAKLLCGGGA-AADRGYFIQPTVFGDVKDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05091-1", "uniprot_id": "ALDH2_HUMAN", "id": "P05091-1", "name": "Aldehyde dehydrogenase, mitochondrial", "aln": "-MLRAA---ARFGPRLGRRLLSAAATQAVPAPNQQPE----VFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGI-AADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLC5-1", "uniprot_id": "Q9VLC5_DROME", "id": "Q9VLC5-1", "name": "aldehyde dehydrogenase (NAD(+))", "aln": "-MLRVLKTGALLRSQAKNFAAAVANYSSLPQPQTTPD----ILYTGVFINNEWHKSKSGKIFETINPTTAEVIAEIQCADKEDIDIAVQAARNAFKLGSPWRRMDASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWADKNHGKTIPMDGDFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPAEQTSLTALYIAQLVKEAGFPEGVVNVVPGFG-TAGAALANHCDVDKVAFTGSTDVGKLIQLASGNTNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKKRTVGNPFDLNTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGGSRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTKDLDKANYIVGGLRAGTVWVNTYNVLAAQAPFGGYKMSGHGRENGEYALSNYTEVKSVIVKVAQKNS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9JHW9-1", "uniprot_id": "AL1A3_MOUSE", "id": "Q9JHW9-1", "name": "Retinaldehyde dehydrogenase 3", "aln": "-MATTN------GAVENG--QPDGKPPALPRPIRNLE----VKFTKIFINNDWHESKSGRKFATYNPSTLEKICEVEEGDKPDVDKAVEAAQAAFQRGSPWRRLDALSRGQLLHQLADLVERDRAILATLETMDTGKPFLHAFFVDLEGCIKTFRYFAGWADKIQGRTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLAWKLAPALCCGNTVVLKPAEQTPLTALYLASLIKEVGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVREAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYGEFVRRSVEFAKKRPVGDPFDAKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSA-MEDRGLFIKPTVFSDVTDNMRIAKEEIFGPVQPILKFKNLEEVIKRANSTDYGLTAAVFTKNLDKALKLAAALESGTVWINCYNAFYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLEEKNP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K4D8-1", "uniprot_id": "AL1A3_RAT", "id": "Q8K4D8-1", "name": "Retinaldehyde dehydrogenase 3", "aln": "-MATAN------GAVENG--QPDGKPPALPRPIRNLE----VKFTKIFINNDWHEPKSGRKFATYNPSTLEKICEVEEGDKPDVDKAVEAAQAAFQRGSPWRRLDALSRGQLLHQLADLIERDRAILATLETMDTGKPFLHAFFVDLEGCIKTFRYFAGWADKIQGRTIPTDDNVMCFTRHEPIGVCGAITPWNFPLLMLAWKLAPALCCGNTVVLKPAEQTPLTALYLASLIKEVGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGRNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYGEFVRRSVEFAKKRPVGDPFDAKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSA-MEDRGLFIKPTVFSDVTDNMRIAKEEIFGPVQPILKFKNLEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWVNCYNAFYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLDEKNP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47895-1", "uniprot_id": "AL1A3_HUMAN", "id": "P47895-1", "name": "Retinaldehyde dehydrogenase 3", "aln": "-MATAN------GAVENG--QPDRKPPALPRPIRNLE----VKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSA-MEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGDKNP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P24549-1", "uniprot_id": "AL1A1_MOUSE", "id": "P24549-1", "name": "Aldehyde dehydrogenase 1A1", "aln": "-MSS-------------------PAQPAVPAPLADLK----IQHTKIFINNEWHNSVSGKKFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLMERDRLLLATMEALNGGKVFANAYLSDLGGCIKALKYCAGWADKIHGQTIPSDGDIFTYTRREPIGVCGQIIPWNFPMLMFIWKIGPALSCGNTVVVKPAEQTPLTALHLASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTQVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDIAVEFAHHGVFYHQGQCCVAASRIFVEESVYDEFVKRSVERAKKYVLGNPLTPGINQGPQIDKEQHDKILDLIESGKKEGAKLECGGGR-WGNKGFFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSVDDVIKRANNTTYGLAAGLFTKDLDKAITVSSALQAGVVWVNCYMMLSAQCPFGGFKMSGNGRELGEHGLYEYTELKTVAMKISQKNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51647-1", "uniprot_id": "AL1A1_RAT", "id": "P51647-1", "name": "Aldehyde dehydrogenase 1A1", "aln": "-MSS-------------------PAQPAVPAPLANLK----IQHTKIFINNEWHDSVSGKKFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLMERDRLLLATIEAINGGKVFANAYLSDLGGSIKALKYCAGWADKIHGQTIPSDGDIFTFTRREPIGVCGQIIPWNFPLLMFIWKIGPALSCGNTVVVKPAEQTPLTALHMASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTQVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDIAVEFAHHGVFYHQGQCCVAASRIFVEESVYDEFVRKSVERAKKYVLGNPLTQGINQGPQIDKEQHDKILDLIESGKKEGAKLECGGGR-WGNKGFFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSIDDVIKRANNTTYGLAAGVFTKDLDRAITVSSALQAGVVWVNCYMILSAQCPFGGFKMSGNGRELGEHGLYEYTELKTVAMKISQKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35945-1", "uniprot_id": "AL1A7_MOUSE", "id": "O35945-1", "name": "Aldehyde dehydrogenase, cytosolic 1", "aln": "-MSS-------------------PAQPAVPAPLANLK----IQHTKIFINNEWHDSVSSKKFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLMERDRLLLATMESMNAGKVFAHAYLLDVEISIKALQYFAGWADKIHGQTIPSDGNIFTYTRREPIGVCGQIIPWNGPLIIFTWKLGPALSCGNTVVVKPAEQTPLTALHMASLIKEAGFPPGVVNIVPGYGPTAGGAISSHMDIDKVSFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDSAVEFAHQGVFFHQGQICVAASRLFVEESIYDEFVRRSVERAKKYILGNPLNSGINQGPQIDKEQHNKILGLIESGKKEGAKLECGGGR-WGNKGFFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSMDDVIKRANNTTYGLAAGVFTKDLDKAITVSSALQAGMVWVNCYLAVPVQCPFGGFKMSGNGRELGEHGLYEYTELKTVAMQISQKNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00352-1", "uniprot_id": "AL1A1_HUMAN", "id": "P00352-1", "name": "Aldehyde dehydrogenase 1A1", "aln": "-MSS-------------------SGTPDLPVLLTDLK----IQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGP-WGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKISQKNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62148-1", "uniprot_id": "AL1A2_MOUSE", "id": "Q62148-1", "name": "Retinal dehydrogenase 2", "aln": "-MTSSEIAMPGEVKADPA--ALMASLQLLPSPTPNLE----IKYTKIFINNEWQNSESGRVFPVCNPATGEQVCEVQEADKVDIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRATLATMESLNGGKPFLQAFYIDLQGVIKTLRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFTWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVVNILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVKRSVERAKRRIVGSPFDPTTEQGPQIDKKQYNKVLELIQSGVAEGAKLECGGKG-LGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALMVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63639-1", "uniprot_id": "AL1A2_RAT", "id": "Q63639-1", "name": "Retinal dehydrogenase 2", "aln": "-MTSSEIAMPGEVKADPA--ALMASLQLLPSPTPNLE----IKYTKIFINNEWQNSESGRVFPVCNPATGEQVCEVQEADKVDIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRATLATMESLNGGKPFLQAFYIDLQGVIKTLRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFTWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVVNILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVKRSVERAKRRIVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKG-LGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALMVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O94788-1", "uniprot_id": "AL1A2_HUMAN", "id": "O94788-1", "name": "Retinal dehydrogenase 2", "aln": "-MTSSKIEMPGEVKADPA--ALMASLHLLPSPTPNLE----IKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKG-LGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4K6I6-1", "uniprot_id": "A0A0B4K6I6_DROME", "id": "A0A0B4K6I6-1", "name": "Aldehyde dehydrogenase domain-containing protein", "aln": "-MMN------KLQKLLAHQLAVSRKWSKFDHTYAQCE----PNYCQLFINNEFVDSVSGKTFATFNPATSKEIVQVSEGDKADIDLAVKAAKKAFHRDSEWRKLSPLQRTNLMNKLCALMDRDKAFLASLETQDNGKPYAEA-LFDVTYSILTLQYYAGWTDKFFGDTIPAGG-FVSMTRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTALHMAALAKEAGFPAGVINVVNGFGPTAGAAISAHPDIAKVAFTGSVEIGRIVMQAAATSNLKRVSLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFVAKAAAKAKARKVGNPFEQNVQQGPQIDDDMLTKVLGYIESGKKEGAKLQAGGKR-IGNVGFFVEPTVFSDVKDDMRIAQEEIFGPVQSIFKFSSLEEMIDRANNVQYGLAAGVITNDINKALKFANNVDAGSVWINCYDAVLPSTPFGGYKHSGIGRELGKDGLDNYLETKTITMKLL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46367-1", "uniprot_id": "ALDH4_YEAST", "id": "P46367-1", "name": "Potassium-activated aldehyde dehydrogenase, mitochondrial", "aln": "MFSRSTLCLKTSASSIGRLQLRYFSHLPMTVPIKLPNGLEYEQPTGLFINNKFVPSKQNKTFEVINPSTEEEICHIYEGREDDVEEAVQAADRAFSNGS-WNGIDPIDRGKALYRLAELIEQDKDVIASIETLDNGKAISSS-RGDVDLVINYLKSSAGFADKIDGRMIDTGRTHFSYTKRQPLGVCGQIIPWNFPLLMWAWKIAPALVTGNTVVLKTAESTPLSALYVSKYIPQAGIPPGVINIVSGFGKIVGEAITNHPKIKKVAFTGSTATGRHIYQSAAAG-LKKVTLELGGKSPNIVFADAELKKAVQNIILGIYYNSGEVCCAGSRVYVEESIYDKFIEEFKAASESIKVGDPFDESTFQGAQTSQMQLNKILKYVDIGKNEGATLITGGER-LGSKGYFIKPTVFGDVKEDMRIVKEEIFGPVVTVTKFKSADEVINMANDSEYGLAAGIHTSNINTALKVADRVNAGTVWINTYNDFHHAVPFGGFNASGLGREMSVDALQNYLQVKAVRAKLDE---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . :****.: . . : * . **:* : : .: . . *:: **.** ** .* *. :.. * . : :*. *:::*: :*::*: : ** : *: : : **::** * * . . *:::*:** * * *** *::: ** .*** * .:::* **.*.*:**::. :.*:* **:*:: *:* .* *:: * : *::****. *: : ::. **:*:*****:.* :: *:::. **: .:: : *: * *.** :*.:.:* :*: . :: :*.*: **.* .. ::* : * :**.* ** * *::****. * : * *.:******* : :*.. :::: **. :** *.: * ::: * . : :* **:* * . ****:: ** *** . .: * : *:: :: ", "identical_positions": 143, "similar_positions": 157, "identity": "27.19%" }, { "cls_id": "homologset.agr.SGD:S000005902", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P26443-1", "uniprot_id": "DHE3_MOUSE", "id": "P26443-1", "name": "Glutamate dehydrogenase 1, mitochondrial", "aln": "MYRRLGEALLLSRAGPAALGSAAADSAALLGWARGQPSAAPQPGLTPVARRHYSEAAADREDDPNFFKMVEGFFDRGASIVEDKLVEDLKTR--ESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCVGVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKVYEG-SILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMS-------------VQESLERKFGKHGGTIP-VVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYN----LGLDLRTAAYVNAIEKVFKVYNEAGVTFT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10860-1", "uniprot_id": "DHE3_RAT", "id": "P10860-1", "name": "Glutamate dehydrogenase 1, mitochondrial", "aln": "MYRRLGEVLLLSRAGPAALGSAAADSAALLGWARGQPSAVPQPGLTPVARRHYSEAATDREDDPNFFKMVEGFFDRGASIVEDKLVEDLKTR--ENEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGLGDKTFVVQGFGNVGLHSMRYLHRFGAKCVGVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKVYEG-SILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMS-------------VQESLERKFGKHGGTIP-VVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYN----LGLDLRTAAYVNAIEKVFKVYNEAGVTFT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00367-1", "uniprot_id": "DHE3_HUMAN", "id": "P00367-1", "name": "Glutamate dehydrogenase 1, mitochondrial", "aln": "MYRYLGEALLLSRAGPAALGSASADSAALLGWARGQPAAAPQPGLALAARRHYSEAVADREDDPNFFKMVEGFFDRGASIVEDKLVEDLRTR--ESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEG-SILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMS-------------VQESLERKFGKHGGTIP-IVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYN----LGLDLRTAAYVNAIEKVFKVYNEAGVTFT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49448-1", "uniprot_id": "DHE4_HUMAN", "id": "P49448-1", "name": "Glutamate dehydrogenase 2, mitochondrial", "aln": "MYRYLAKALLPSRAGPAALGSAANHSAALLGRGRGQPAAASQPGLALAARRHYSELVADREDDPNFFKMVEGFFDRGASIVEDKLVKDLRTQ--ESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTENELEKITRRFTMELAKKGFIGPGVDVPAPDMNTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFRDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEG-SILEVDCDILIPAATEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNILVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLLS-------------VQESLERKFGKHGGTIP-IVPTAEFQDSISGASEKDIVHSALAYTMERSARQIMHTAMKYN----LGLDLRTAAYVNAIEKVFKVYSEAGVTFT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54385-1", "uniprot_id": "DHE3_DROME", "id": "P54385-1", "name": "Glutamate dehydrogenase, mitochondrial", "aln": "MYHLKSLARQGARRQQELATLAKALPTAVMQSSRGYATEHQIP-------DRLKDVPTAK--DPRFFDMVEYFFHRGCQIAEESLVDDMKGK--LTRDEKKQKVKGILMLMQPCDHIIEIAFPLRRDAGNYEMITGYRAQHSTHKTPTKGGIRFSLDVSRDEVKALSALMTFKCACVDVPFGGAKAGLKINPKEYSEHELEKITRRFTLELAKKGFIGPGVDVPAPDMGTGEREMSWIADTYAKTIGHLDINAHACVTGKPINQGGIHGRVSATGRGVFHGLENFINEANYMSQIGTTPGWGGKTFIVQGFGNVGLHTTRYLTRAGATCIGVIEHDGTLYNPEGIDPKLLEDYKNEHGTIVGYQNAKPYEGENLMFEKCDIFIPAAVEKVITSENANRIQAKIIAEAANGPTTPAADKILIDRNILVIPDLYINAGGVTVSFFEWLKNLNHVSYGRLTFKYERESNYHLLASVQQSIERIINDESVQESLERRFGRVGGRIP-VTPSESFQKRISGASEKDIVHSGLDYTMERSARAIMKTAMKYN----LGLDLRTAAYVNSIEKIFTTYRDAGLAF-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCN3-1", "uniprot_id": "Q9VCN3_DROME", "id": "Q9VCN3-1", "name": "Glutamate dehydrogenase", "aln": "MLRYTARILNGIYP--------------LMPRQVLKRSAHQVP-------EKLKKVETDK--DPEFSEMVLYYYHKAAQTMEPALLKEMEKYPHMKPEERQARVTAILNLLGSVSTSVEVNFPIVRKNGTYEIISGYRSHHVRHRLPLKGGIRYALDVNESEVKALAAIMTFKCACVNVPYGGSKGGICIDPKKYTVDELQTITRRYTMELLKRNMIGPGIDVPAPDVNTGPREMSWIVDQYQKTFGYKDINSSAIVTGKPVHNGGINGRHSATGRGVWKAGDLFLKDKEWMDLLKWKTGWKDKTVIVQGFGNVGSFAAKYVHEAGAKVIGIKEFDVSLVNKDGIDINDLFEYTEEKKTIKGYPKAQESKE-DLLVAETDILMPCATQKVITTDNAKDIKAKLILEGANGPTTPSGEKILLDKGVLLVPDLYCNAGGVTVSYFEYLKNINHVSYGKMNSKSTSELIIELMNS-------------INESLHECP---DSQLPNICPNKKLKRIQQCTTEADIVDSALQTVMESAARGIKEMAHKFE----LCNDLRRAAYVWSSFKIFQAMESSGISQQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07262-1", "uniprot_id": "DHE4_YEAST", "id": "P07262-1", "name": "NADP-specific glutamate dehydrogenase 1", "aln": "------------------------------------------------------------------------MSEPEFQQAYEEVVSSLEDS---TLFEQHPEYRKVLPIVSVPERIIQFRVTWENDKGEQEVAQGYRVQYNSAKGPYKGGLRFHPSVNLSILKFLGFEQIFKNSLTGLDMGGGKGGLCVDLKGRSNNEIRRICYAFMRELSRH--IGQDTDVPAGDIGVGGREIGYLFGAYRS----YKNSWEGVLTGKGLNWGGSLIRPEATGYGLVYYTQAMIDYATNG-----KESFEGKRVTISGSGNVAQYAALKVIELGGTVVSLSDSKGCIISETGITSEQVADISSAKVNFKSLEQIVNEYS---TFSENKVQYIAGAR---PWTHVQKVDIALPCATQNEVSGEEAKALVAQGVKFIAEGSNMGSTPEAIAVFETARSTATGPSEAVWYGPPKAANLGGVAVS---------------G---------------LEMAQNSQRITWTSER--VDQELKRIMINCFNECIDYAKKYTKDGKVLPSLVKGANIASFIKVSDAMFDQGDVF-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . ::..:. . ::: . :* :: . :.. .. .. * *: *** :: : * ***:*: .*. . :* *. :* : ..: **.*.*: :: * : .*:. * : ** :: ** . **** *:..* **:.:: . * . . . . :*** : ** * .*** *: : ::. . . .* . :.* ***. .: : . *.. :.: : . : . ** : : : . : .: . : . .: .. . . :. :. : * : .. :. : :: . .: ::: ** :. . : : . . . ::* *.. * * . . * *: : .* .* : : *: . . * ", "identical_positions": 66, "similar_positions": 151, "identity": "11.4%" }, { "cls_id": "homologset.agr.SGD:S000005905", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VPE0-1", "uniprot_id": "Q9VPE0_DROME", "id": "Q9VPE0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "------------MAQLKFLRPLVKVLVNRSGIGKASVWHAVIVTFMHYFSWGLLTVPFIEKLSGSFGNRVLLVDGLVYGVRGILGFVTTP----------VMGAISDFHGRKVVMLLAVATTYAP---IPFMMLKSWWFFAILTVSSICGSTYSSSLAYVADTTTVENRSKG---YGIVAASFGAGIAFSPSLGNYLMKSYGSASVILIAAITGLINIMFIIFAVPESLVLKEKNNMLDEESDN-----KMEDINPKERKEILNREEKLNNHVSANKSNHGTSQNLVTNKELGQQFNKEENLQNDLTEKEKIDNGSLNSSDLWEVLRKSRKDKNLLVIYLITFLSIWPFAGVDSTAPVYLKTNMGFEYEEVSMMLGLLSVLAITSNLLLGYIINIVGAKWSIRLGLLLLLLQLFFFGFGTHHWMYWLSSILAALAT-----IIPAANNAVASIYASPDNRGAVLGIISGIECLSEGVGPAFFGVLFFIFQDDSKN--KVNSPIS------MPFVISAIGVFVAIVLTGFIKKETVEKAPLIYKIIDDASEDEVEPLAKTTFKYEKNNGYVKLEIDDNYDSDCKEHSFK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPD9-1", "uniprot_id": "Q9VPD9_DROME", "id": "Q9VPD9-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "------------MAQLKFLRPLVKVLVNRSGIGKASVWHAVIVTFMHYFSWGLLTVPFIEKLSGSFGNRVLLVDGLVYGVRGILGFVTTP----------VMGAISDFHGRKVVMLLAVATTYAP---IPFMMLKSWWFFAILTVSSICGSTYSSSLAYVADTTTVENRSKG---YGFVAASFGAGIAFSPSLGNYLMKSYGSASVILIATITGMINILFIIFAVPESLVLKEKKVILNENNDNKVEDTKVDDISPKEKKENLNGEGKVN--VEVNKP---TSQNIVTNKELDQQFSKEENLQNDLTEKEKIDNGSLNSSDLWEVLRKSRKDKNLLVIYLITFLSIWPFAGVDSTAPVYLKTNMGFEYEEVSMMLGLLSVLAITSNILLGYIMNIVGAKWSIRLGLLLLFLQMLFFGFGTHHWMYWLSSILAALAT-----IIPAANNAVASIYASPDNRGAVLGIISGIECLSEGVGPAFFGLLFFIFQDDSETDLKVNSPIS------MPFVISAISVFVAIVLSSFIKKDTLGNE-------ETRVANENIP---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPD8-1", "uniprot_id": "Q9VPD8_DROME", "id": "Q9VPD8-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "------------MSKFG-LKKLLVSLASTSGIGKPSVGHILVVVFLEYFAWGLLTMPMIATLKETFPDHTFLMNGLVMGVKGILSFLSSP----------LIGALSDIYGRKVLLLITVIFTSLP---IPMMTMDNWWFFVISSISGVLGVSFSVAFAYVADVTTKEERSRS---YELVSATFAASLVIAPAMGNLIMDRYGINTVVLVATLVSTTNVMFVLLAVPETLQQNVRSTGL-----------------------------------------------------------------------------SWKQADPFLSLRRVGSDPNVLLLCVVMFTFLLPEAGEYSSVPAYLKLTMGFDFTELSTLVAFMAILGISINVTLGSIVKTLGAKNAIILGLLLELLQLILFAIGYEKWQMWLAGNVAALSS-----ITFPAVSAYVSLYTDVETQGAVQGMITGMSGLCSGLGPALFGIVFYLSDMDLDKNRILIGSVSGDRTVTNPFMIGAISVFIGILLASYIPDEKVSRG----RREEFSALKYIIEMEEATTI--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08902-1", "uniprot_id": "AMF1_YEAST", "id": "Q08902-1", "name": "Low affinity ammonium transporter", "aln": "MSTSSSVTQKNLDTNAEALKKEDKVLSEFDIQDERPKSLLWESAFVGVLCSAQLMT--QAGLGQSLAPLHIIGNSFGTTNAGQLSWFASAYSLTVGTFILIAGRLGDIFGHKKFFVLGFFWYALWSLLAGFSVYSNQIFFDCCRAFQGMGPAFLLPNAIAILGRTYKPGRRKNMVFSLFGASAPGGFFLGAVFSSMLGQLAWWPWAYWIMGIACFVLAVAGYFVIPHTPMPSRDASSFKLLERIDFAGSVTGVVGLILFNFAWNQGPVVG------------------------WQTPYTYALLIVGTFFLVIFAYIESRAAFPLLPFAALSSDTAFVLSCIAAGWASFGIWIFYTWQFMEDSRGQTPLLSSAQFSPVAISGFCAAVTTGFLLSHTPPSTVMLFAMTAFTVGTILIATAPVHQTYWAQTFVSIIVMPWGMDMSFPAATIMLSDSMPHEHQGLAASLVNTVVNYSISIG---LGIAGTIESRVNDGGAKPLKGYR------CSWYMGIGLSGLGIFVAATYAWSTFMKS-----KKRISEKQHFIE---------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: *: * . . .: . .*: :. . * * :: :: :.: * *.:.::. : * :.*:.*:* .::: . : .. ** * :: . * . * : : : :..*: ..: :.. :.. : . . : :. : :.:*.: . : :. : * . : .: . . . ::: . * * .. ::: .: : * ::. .. : :.: : :::. . : * :: : : .* . * : :* . .::. : . .:* :*: : . . .: :. :.*.::. ... . . ", "identical_positions": 29, "similar_positions": 149, "identity": "4.93%" }, { "cls_id": "homologset.agr.SGD:S000005911", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q672J9-1", "uniprot_id": "NOX3_MOUSE", "id": "Q672J9-1", "name": "NADPH oxidase 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPVCWILNESGSFVVALLWLA------------------------------------------------------------------------------------------------VNAYLFIDTFFWYTEEEAFFYTRVILGSALAWARASAVCLNFNCMLILLPVSRNFISLVRGTSVCCRGPWRRQ-------------------------------------------------------------------------------------------------------------------------------------LDKNLNFHKLVAYGIAVNSVIHIVAHLFNLERYHLGQAKDAEGLLAALSKLGDAPNE-SYLNPVRTFDMGTTTELLMTVS---GITGLGISLALVFIMTSSTEFIRRS-----SYELFWYTHHIFVFFFISLAIHGGGRIIRGQT--------------PESLRLHNVTYCRDHYA--------------EWQAAA-LCPVPQFSGKEPSAWKWALGPVVLYACERIIRFWRSH---QEVVITKVVSHPSAVLELHMKK--RDFKMAPGQYIFIQCP-SVSPLEWHPFTLTSAPQE--DFFSVHIRASGDWTEALLKAFR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VEGQAPSELCSMPR-------------------------------------LAVDGPFGGSLADVFHYPVSVCIATGIGVTPFASLLKSVWYKCCES----------------QSLPELSKVYFYWICRDAGAFEWFADLLLSLETRMSEQG--KAHLLSYHIYLTGWDEN--------QAIHIALHWDESLDVITGLKQKAFYGRPNWNDEFKQIAYNH-PSSSIGVFFCGSK-AMSKTLQKMCRLYSSVDPRGVHFYYNKENF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q672K1-1", "uniprot_id": "NOX3_RAT", "id": "Q672K1-1", "name": "NADPH oxidase 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPTCWILNESVSFVVALLWLA------------------------------------------------------------------------------------------------INIYLFIDTFCWYAEEESFFYTRVILGSALAWARASAVCLNFNCMLILLPVSRNFVSLVRGTSVCCRGPWRRQ-------------------------------------------------------------------------------------------------------------------------------------LDKNLKFHKLVAYGIAVNSVIHIVAHLFNLERYHLGQAKDAEGLLAALSKLGNAPNE-SYLNPVRTLYTGTTTQLLMTVS---GITGLVISLALILIMTSSTEFIRQS-----SYELFWYTHHIFIFLFISLAIHGGGRIIRGQT--------------PESLRLHNVTFCRDHFD--------------EWQEAA-SCPVPQFSGKEPSAWKWTLGPVVLYACEIIIRFWRSH---QEVVITKVVSHPSAVLELHMKK--RDFKMAPGQYIFIQCP-SISPLEWHPFTLTSAPQE--DFFSVHIRASGDWTEALLKAFG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AEGQAPSELCSMPR-------------------------------------LAVDGPFGGSLADVFHYPVSVCIATGIGVTPFASLLKSVWYKCCES----------------QSLPGLSKVYFYWICRDAAAFEWFADLLLSLETQMSEQG--KAHLLSYHIYLTGWDEY--------QAIHIALHWDESLDVITGLKQKTFYGRPNWNEEFKQIAYNH-PSSSIGVFFCGPK-AMSKTLQKMCRLYSSSDPRGVHFYYNKENF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HBY0-1", "uniprot_id": "NOX3_HUMAN", "id": "Q9HBY0-1", "name": "NADPH oxidase 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMGCWILNEGLSTILVLSWLG------------------------------------------------------------------------------------------------INFYLFIDTFYWYEEEESFHYTRVILGSTLAWARASALCLNFNCMLILIPVSRNLISFIRGTSICCRGPWRRQ-------------------------------------------------------------------------------------------------------------------------------------LDKNLRFHKLVAYGIAVNATIHIVAHFFNLERYHWSQSEEAQGLLAALSKLGNTPNE-SYLNPVRTFPTNTTTELLRTIA---GVTGLVISLALVLIMTSSTEFIRQA-----SYELFWYTHHVFIVFFLSLAIHGTGRIVRGQT--------------QDSLSLHNITFCRDRYA--------------EWQTVA-QCPVPQFSGKEPSAWKWILGPVVLYACERIIRFWRFQ---QEVVITKVVSHPSGVLELHMKK--RGFKMAPGQYILVQCP-AISSLEWHPFTLTSAPQE--DFFSVHIRAAGDWTAALLEAFG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AEGQALQEPWSLPR-------------------------------------LAVDGPFGTALTDVFHYPVCVCVAAGIGVTPFAALLKSIWYKCSEA----------------QTPLKLSKVYFYWICRDARAFEWFADLLLSLETRMSEQG--KTHFLSYHIFLTGWDEN--------QALHIALHWDENTDVITGLKQKTFYGRPNWNNEFKQIAYNH-PSSSIGVFFCGPK-ALSRTLQKMCHLYSSADPRGVHFYYNKESF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61093-1", "uniprot_id": "CY24B_MOUSE", "id": "Q61093-1", "name": "NADPH oxidase 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNWAVNEGLSIFVILVWLG------------------------------------------------------------------------------------------------LNVFLFINYYKVYDDGPKYNYTRKLLGSALALARAPAACLNFNCMLILLPVCRNLLSFLRGSSACCSTRIRRQ-------------------------------------------------------------------------------------------------------------------------------------LDRNLTFHKMVAWMIALHTAIHTIAHLFNVEWCVNARVGISDRYSIALSDIGDNENE-EYLNFAREKIKNPEGGLYVAVTRLAGITGIVITLCLILIITSSTKTIRRS-----YFEVFWYTHHLFVIFFIGLAIHGAERIVRGQT--------------AESLEEHNLDICADKIE--------------EWGKIK-ECPVPKFAGNPPMTWKWIVGPMFLYLCERLVRFWRSQ---QKVVITKVVTHPFKTIELQMKK--KGFKMEVGQYIFVKCP-KVSKLEWHPFTLTSAPEE--DFFSIHIRIVGDWTEGLFNACG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CDKQEFQDAWKLPK-------------------------------------IAVDGPFGTASEDVFSYEVVMLVGAGIGVTPFASILKSVWYKYCDN----------------ATSLKLKKIYFYWLCRDTHAFEWFADLLQLLETQMQERN--NANFLSYNIYLTGWDES--------QANHFAVHHDEEKDVITGLKQKTLYGRPNWDNEFKTIASEH-PNTTIGVFLCGPE-ALAETLSKQSISNSESGPRGVHFIFNKENF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ERL1-1", "uniprot_id": "Q9ERL1_RAT", "id": "Q9ERL1-1", "name": "NADPH oxidase 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNWAVNEGLSIFVILVWLG------------------------------------------------------------------------------------------------LNVFLFVKYYKVYDDEPKYNYTRKLLGSALALARAPAACLNFNCMLILLPVCRNLLSFLRGSSACCSTRIRRQ-------------------------------------------------------------------------------------------------------------------------------------LDRNLTFHKMVAWMIALHTAIHTIAHLFNVEWCVNARVGTSDPYSVALSNIGDKENE-EYLNFAREKIKNPEGGLYVAVTRLAGITGIVITLCLILIITSSTKTIRRS-----YFEVFWYTHHLFVIFFIGLAIHGAERIVRGQT--------------SDSLKEHNLDVCADKIK--------------EWGKIK-ECPVPKFAGNPPMTWKWIVGPMFLYLCERLVRFWRSQ---QKVVITKVVTHPFKTIELQMKK--KGFKMEVGQYIFVKCP-QVSKLEWHPFTLTSAPEE--DFFSIHIRIVGDWTEGLFNACG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CDKQEFQDAWKLPK-------------------------------------IAVDGPFGTASEDVFSYEVVMLVGAGIGVTPFASILKSVWYKYCDN----------------ATSLRLKKIYFYWLCRDTHAFEWFADLLQLLETQMQERN--NANFLSYNIYLTGWDES--------QANHFAVHHDEEKDVITGLKQKTLYGRPNWDNEFKTIASQH-PNTRIGVFLCGPE-ALAKTLSKQSISNSESGPRGVHFIFNKENF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04839-1", "uniprot_id": "CY24B_HUMAN", "id": "P04839-1", "name": "NADPH oxidase 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNWAVNEGLSIFVILVWLG------------------------------------------------------------------------------------------------LNVFLFVWYYRVYDIPPKFFYTRKLLGSALALARAPAACLNFNCMLILLPVCRNLLSFLRGSSACCSTRVRRQ-------------------------------------------------------------------------------------------------------------------------------------LDRNLTFHKMVAWMIALHSAIHTIAHLFNVEWCVNARVNNSDPYSVALSELGDRQNE-SYLNFARKRIKNPEGGLYLAVTLLAGITGVVITLCLILIITSSTKTIRRS-----YFEVFWYTHHLFVIFFIGLAIHGAERIVRGQT--------------AESLAVHNITVCEQKIS--------------EWGKIK-ECPIPQFAGNPPMTWKWIVGPMFLYLCERLVRFWRSQ---QKVVITKVVTHPFKTIELQMKK--KGFKMEVGQYIFVKCP-KVSKLEWHPFTLTSAPEE--DFFSIHIRIVGDWTEGLFNACG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CDKQEFQDAWKLPK-------------------------------------IAVDGPFGTASEDVFSYEVVMLVGAGIGVTPFASILKSVWYKYCNN----------------ATNLKLKKIYFYWLCRDTHAFEWFADLLQLLESQMQERN--NAGFLSYNIYLTGWDES--------QANHFAVHHDEEKDVITGLKQKTLYGRPNWDNEFKTIASQH-PNTRIGVFLCGPE-ALAETLSKQSISNSESGPRGVHFIFNKENF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CIZ9-1", "uniprot_id": "NOX1_MOUSE", "id": "Q8CIZ9-1", "name": "NADPH oxidase 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGELRGSRGPLQRIQIAPREAPNLHLTMGNWLVNHWLSVLFLVSWLG------------------------------------------------------------------------------------------------LNIFLFVYAFLNYEKSDKYYYTREILGTALALARASALCLNFNSMMILIPVCRNLLSFLRGTCSFCNRTLRKP-------------------------------------------------------------------------------------------------------------------------------------LDHNLTFHKLVAYMICIFTVIHIIAHLFNFERYRRSQQAMDGSLASVLSSLSHPEKEDSWLNPIQSPNMTVMYAAFTSIA---GLTGVIATVALVLMVTSAMEFIRRN-----YFELFWYTHHLFIVYIICLGIHGLGGIVRGQT--------------EESLGESHPHNCSHSFH--------------EWDDHKGSCRHPHFAGHPPESWKWILAPIAFYIFERILRFYRSQ---QKVVITKVVMHPSNVLELQMRK--RGFSMEVGQYIFVNCP-SISFLEWHPFTLTSAPEE--EFFSVHIRAAGDWTRNLIRTFE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QQHS------PMPR-------------------------------------IEVDGPFGTVSEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQRA----------------DNKLKTQKIYFYWICRETGAFAWFNNLLNSLEQEMEELG--KMDFLNYRLFLTGWDSN--------IAGHAALNFDRATDILTGLKQKTSFGRPMWDNEFSRIATAH-PKSAVGVFLCGPR-TLAKSLRKRCQRYSSLDPRKVQFYFNKETF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JHI8-1", "uniprot_id": "NOX4_MOUSE", "id": "Q9JHI8-1", "name": "NADPH oxidase 4", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAVSWRSWLANEGVKHLCLLIWLS------------------------------------------------------------------------------------------------LNVLLFWKTFLLYNQGPEYYYIHQMLGLGLCLSRASASVLNLNCSLILLPMCRTVLAYLRGSQKVPSRRTRRL-------------------------------------------------------------------------------------------------------------------------------------LDKSKTLHITCGVTICIFSGVHVAAHLVN-----------------ALNFSVNYSEDFLELNAARYQNEDPRKLLFTTIP---GLTGVCMVVVLFLMVTASTYAIRVS-----NYDIFWYTHNLFFVFYMLLLLHVSGGLLKYQTNVDTHPPGCISLNQTSSQNMSIPDYVSEHFHGSLPRGFSKLEDRYQKTLVKICLEEPKFQAHFPQTWIWISGPLCLYCAERLYRCIRSN---KPVTIISVINHPSDVMELRMIK--ENFKARPGQYIILHCP-SVSALENHPFTLTMCPTETKATFGVHFKVVGDWTERFRDLLLP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PSSQDSEILPFIHSRNYPK-------------------------------------LYIDGPFGSPFEESLNYEVSLCVAGGIGVTPFASILN----TLLDD----------------WKPYKLRRLYFIWVCRDIQSFQWFADLLCVLHNKFWQEN--RPDFVNIQLYLSQTDGI--------QKIIGEKYHT--------LNSRLFIGRPRWKLLFDEIAKCN-RGKTVGVFCCGPS-SISKTLHSLSNRNNS---YGTKFEYNKESFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q924V1-1", "uniprot_id": "NOX4_RAT", "id": "Q924V1-1", "name": "NADPH oxidase 4", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALSWRSWLANEGVKHLCLLVWLS------------------------------------------------------------------------------------------------LNVLLFWKTFLLYNQGPEYYYIHQMLGLGLCLSRASASVLNLNCSLILLPMCRTVLAYLRGSQKVPSRRTRRL-------------------------------------------------------------------------------------------------------------------------------------LDKSKTLHITCGITICIFSGVHVAAHLVN-----------------ALNFSVNYSEHFLALNAARYQNEDPRKLLFTTVP---GLTGVCMVVVLFLMVTASTYAIRVS-----NYDIFWYTHNLFFVFYMLLLLHVSGGLLKYQTNLDTHPPGCISLNRTPSQNMSIADYVSEHFHGSLPGGFSKLEDHYQKTLVKICLEEPKFQAHFPQTWIWISGPLCLYCAERLYRCIRSN---KPVTIISVINHPSDVMELRMIK--ENFKARPGQYIILHCP-SVSALENHPFTLTMCPTETKATFGVHFKVVGDWTERFRDLLLP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PSSQDSEILPFIQSRNYPK-------------------------------------LYIDGPFGSPFEESLNYEVSLCVAGGIGVTPFASILN----TLLDD----------------WKPYKLRRLYFIWVCRDIQSFQWFADLLYVLHNKFWQEN--RPDFVNIQLYLSQTDGI--------QKIIGEKYHT--------LNSRLFIGRPRWKLLFDEIAKCN-RGKTVGVFCCGPS-SISKTLHNLSNRNNS---YGTKFEYNKESFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NPH5-1", "uniprot_id": "NOX4_HUMAN", "id": "Q9NPH5-1", "name": "NADPH oxidase 4", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAVSWRSWLANEGVKHLCLFIWLS------------------------------------------------------------------------------------------------MNVLLFWKTFLLYNQGPEYHYLHQMLGLGLCLSRASASVLNLNCSLILLPMCRTLLAYLRGSQKVPSRRTRRL-------------------------------------------------------------------------------------------------------------------------------------LDKSRTFHITCGVTICIFSGVHVAAHLVN-----------------ALNFSVNYSEDFVELNAARYRDEDPRKLLFTTVP---GLTGVCMVVVLFLMITASTYAIRVS-----NYDIFWYTHNLFFVFYMLLTLHVSGGLLKYQTNLDTHPPGCISLNRTSSQNISLPEYFSEHFHEPFPEGFSKPAEFTQHKFVKICMEEPRFQANFPQTWLWISGPLCLYCAERLYRYIRSN---KPVTIISVMSHPSDVMEIRMVK--ENFKARPGQYITLHCP-SVSALENHPFTLTMCPTETKATFGVHLKIVGDWTERFRDLLLP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PSSQDSEILPFIQSRNYPK-------------------------------------LYIDGPFGSPFEESLNYEVSLCVAGGIGVTPFASILN----TLLDD----------------WKPYKLRRLYFIWVCRDIQSFRWFADLLCMLHNKFWQEN--RPDYVNIQLYLSQTDGI--------QKIIGEKYHA--------LNSRLFIGRPRWKLLFDEIAKYN-RGKTVGVFCCGPN-SLSKTLHKLSNQNNS---YGTRFEYNKESFS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8DWJ8-1", "uniprot_id": "A8DWJ8_DROME", "id": "A8DWJ8-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNADQESNNHRGSVSSSRSLEIPATPSRSPKKVSFSDELPQSQTPAQQPINQQSAPTVVSHVLQQAAQYLERLHGARDSAEEKTEEVQPERADIRDSSDTSEAAVLDLDALDASADEPAANAGPIVASSPSILIGSVNRQEAIGSANGNGNANPNQRQSNLYMERYNLNLDKNCSSMELEARREKQRWLLISECSALFDEGEGKHTREAFRKLFLDEEFQQKLFQLFDLERNGYLLQDRWIEHLKGRLTDDRQMDFAEQIESVAYVICGENKRVSFKNFRDIWHTRGILDKLYRLIELDGSNLVSTNQVMEFISHLTNSRPRTGFDKSSLARLEQLFRTTVGNEQEIRREEFQKIVTSKNPFFTERVFQIFDKDNSGSISLQEF-----IDAIHQFSGQSADDKIRFLFKVYDIDGDGLIQHKELHDVIRHCIKENGMEFSEDQIEDLTSAMFEDADPHNSGEITYEALKNQLHKHGGLLENLSITIDRWLVPIAEDRQAGGAAKSGFW--------------------------------------------------------------------------------------------------------------------------NSLPHQFSLAYMKNNQVFVTYLFFYITVNLCLFISRAIQYRASNGFVIIARACGQCLNFNCAWVLVLMLRHSLTYLRGRGLSSYLPLDHHVYLHKLTGITISVLSLIHTI-----MHLFNFSIIVINDPNINAGHYTIGEWLLTDRPGLFGLIPGCANPTGVALLAILVVMFVCSQPFVRRKGS----FEVFYWTHLLYVPFWILCLFHGPNFWKWFLLPGLVYIVERALRFIWMRGEHGKTYISSGLLLPSKVVHLVIKRP-HHFNFRPGDYVFVNIP-AIANYEWHPFTISSAPEQ-EDYMWLHIRTVGEWTNRLYRYFEREQQKLQQSGSSQEIPQHMHAIPTPSFMLLNEARNPAIAGERSATPQTDFLAKNLGVQAVPPVRPPRQNRKPAPGAPIDPPATGVNRIRSIKKTLQRTFSRKEAVDPKKGIPNGAFIADGEREDSNLKQRPLEKSISLPDISVKSKKRSRLKALRALGRSESESAFDEKRVRRARNNSVGLAYLSPQNKSLAQSFRYMRTKPTIIAFKTPSMEEREHQVAAGEANGASPASRAEQGQLSSRMDSADKLQLARLSLSAEGASKPLEDQTQTGSPSRKSILRRPTFLRSLSASINNRTGGGGGGSTGSSTTNSGGKVTLDAGVMEIFIDGPYGAPSSHIFGAQHAVLIGTGIGVTPFASILQSIMHRYWKARHSCPRCQFEWASEIPKSVMNLRKVDFFWINRDQRSFEWFVNLLSQLEIEQAELGGAMERFLDMHMYITSALQRTDMKAVGLQLALDLLHEKGKRDLITGLKTRTNAGRPNWDKVFKQLQAQQ-KGK-VTVFYCGPP-QLAKTLRYKCD--------QYGFAFRKECF-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q96PH1-1", "uniprot_id": "NOX5_HUMAN", "id": "Q96PH1-1", "name": "NADPH oxidase 5", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNTSGDPAQTGPEGCRG----------------------TMSAEEDAR-----------WLRWVTQQFKTIAGEDGE------------------------ISLQEFKA---------------------ALHVKESF--------FAERFFALFDSDRSG-------------------TITLQELQEALTLLIHG-----------------SPMDKLKFLFQVYDIDVCARQGASAGTEWGAGAGP--HWASSPLG-----------------------------------------------------------------------------------TGSGSIDPDELRTVLQSCLRESAISLPDEKLDQLTLALFESADADGNGAITFEELRDELQRFPGVMENLTISAAHWLTAPAPRPRP------------------------------------------------------------------------------------------------------------------------------------RRPRQLTRAYWHNHRSQLFCLATYAGLHVLLFGLAASAHRDLGASVMVAKGCGQCLNFDCSFIAVLMLRRCLTWLRATWLAQVLPLDQNIQFHQLMGYVVVGLSLVHTV-----AHTVNF----VLQAQAEASPFQFWELLLTTRPG-IGWVHGSASPTGVALLLLLLLMFICSSSCIRRSGH----FEVFYWTHLSYLLVWLLLIFHGPNFWKWLLVPGILFFLEKAIGLAVSR--MAAVCIMEVNLLPSKVTHLLIKRP-PFFHYRPGDYLYLNIP-TIARYEWHPFTISSAPEQ-KDTIWLHIRSQGQWTNRLYESFK-------------------------------------------------------------------------------------------------------ASDP-------------------------------------------------LGRGS-------KRLSRSVT---------------------MR-------------------------------------------------------------------KSQRSSKGSEILLEKHKFCN-----------------------------------IKCYIDGPYGTPTRRIFASEHAVLIGAGIGITPFASILQSIMYRHQKRKHTCPSCQHSWIEGVQDN-MKLHKVDFIWINRDQRSFEWFVSLLTKLEMDQAEEA-QYGRFLELHMYMTSALGKNDMKAIGLQMALDLLANKEKKDSITGLQTRTQPGRPDWSKVFQKVAAEK-KGK-VQVFFCGSP-ALAKVLKGHCE--------KFGFRFFQENF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NRD8-1", "uniprot_id": "DUOX2_HUMAN", "id": "Q9NRD8-1", "name": "Dual oxidase 2", "aln": "----------------------------------MLRARPEALMLLGALLTGSLGPSGNQDALSLPWEVQRYDGWFNNLRHHERGAVGCRLQRRVPANYADGVYQALEEPQLPNPRRLSNAATRGIAGLPSLHNRTVLGVFFGYHVLSDVVSVETPGCPAEFLNIRIPPGDPVFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDLANQVTGWLDGSAIYGSSHSWSDALRSFSGGQLASGPDPAFPRDSQNPLLMWAAPDP-ATGQNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFLQKTLPEYTGYRPFLDPSISPEFVVASEQFFSTMVPPGVYMRNASCHFRKVLNKGFQSSQALRVCNNYWIRENPNLNSTQEVNELLLGMASQISELEDNIVVEDLRDYWPGPGKFSRTDYVASSIQRGRDMGLPSYSQALLAFGLDIPRNWSDLNPNVDP---QVLEATAALYNQDLSQLELLLGGLLESHGDPGPLFSAIVLDQFVRLRDGDRYWFENTRNGLFSKKEIEDIRNTTLRDVLVAVINIDPSALQPNVFVWHKGAPCPQPKQLTTDGLPQCAPLTVLDFFEGSSPGFAITIIALCCLPLVSLLLSGVVAYFRG--REHKKLQKKLKESVKKEAAKDGVPAMEWPGPKERSSPIIIQLLSDRCLQVLNRHLTVLRVVQLQPLQQVNLILSNN---RGCRTLLLKIPKEYDLVLLFSSEEERGAFVQQLWDFCVRWALGLHVAEMSEKELFRKAVTKQQRERILEIFFRHLFAQVLDINQADAGTLPLDSSQ-KVREALTCELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMKGSPEDKSRLMFTMYDLDENGFLSKDEFFTMMRSFIEIS-NNCLSKAQLAEVVESMFRESGFQDKEELTWEDFHFMLRDHDSELRFTQLCVKGGGGGGNGIRDIFK------QNISCRVSFITRTPGERSHPQGLGPPAPEAPELGGP--GLKKRFGKKAAVPTPRLYTEALQEKMQRGFLAQKLQQYKRFVENYRRHIVCVAIFSAICVGVFADRAYYYGFASPPSDIAQTTLVGIILSRGTAASVSFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRWIAMAAVVLAILHSAGHAVNVYIFSVSPLSLLACIFPNVFVNDGSKLPQKFYWWFFQTVPGMTGVLLLLVLAIMYVFASHHFRRRSFRGFWLTHHLYILLYALLIIHGSYALIQLPTFHIYFLVPAIIYGGDKLVSLSRKK---VEISVVKAELLPSGVTYLQFQRP-QGFEYKSGQWVRIACL-ALGTTEYHPFTLTSAPHE--DTLSLHIRAVGPWTTRLREIYSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKGNGCAGYPK-------------------------------------LYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFKSSLG-----------------SQMLCKKIYFIWVTRTQRQFEWLADIIQEVEEND------HQDLVSVHIYVTQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEPFFNSLQEVHPQVRKIGVFSCGPP-GMTKNVEKACQLVNRQ--DRAHFMHHYENF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NRD9-1", "uniprot_id": "DUOX1_HUMAN", "id": "Q9NRD9-1", "name": "Dual oxidase 1", "aln": "--------------------------------------MGFCLALAWTLLVGAWTPLGAQNPIS--WEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPHLPNPRDLSNTISRGPAGLASLRNRTVLGVFFGYHVLSDLVSVETPGCPAEFLNIRIPPGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPANQVTGWLDGSAIYGSSHSWSDALRSFSRGQLASGPDPAFPRDSQNPLLMWAAPDP-ATGQNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFLQKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDFWPGPLKFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSNDTVLEATAALYNQDLSWLELLPGGLLESHRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNGLFSKKEIEEIRNTTLQDVLVAVINIDPSALQPNVFVWHKGDPCPQPRQLSTEGLPACAPSVVRDYFEGSGFGFGVTIGTLCCFPLVSLLSAWIVARLRM--RNFKRLQGQDRQSIVSEKLVGGMEALEWQGHKEPCRPVLVYLQPGQ-IRVVDGRLTVLRTIQLQPPQKVNFVLSSN---RGRRTLLLKIPKEYDLVLLFNLEEERQALVENLRGALKESGLSIQEWELREQELMRAAVTREQRRHLLETFFRHLFSQVLDINQADAGTLPLDSSQ-KVREALTCELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMKGSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEIS-NNCLSKAQLAEVVESMFRESGFQDKEELTWEDFHFMLRDHNSELRFTQLCVKG-VEVPEVIKDLCRRASYISQDMICPSPRVSARCSRSDIETELTPQRLQCPMDTDPPQEIRRRFGKKVTSFQPLLFTEAHREKFQRSCLHQTVQQFKRFIENYRRHIGCVAVFYAIAGGLFLERAYYYAFAAHHTGITDTTRVGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRLIASTAIVLTVLHSVGHVVNVYLFSISPLSVLSCLFPGLFHDDGSELPQKYYWWFFQTVPGLTGVVLLLILAIMYVFASHHFRRRSFRGFWLTHHLYILLYVLLIIHGSFALIQLPRFHIFFLVPAIIYGGDKLVSLSRKK---VEISVVKAELLPSGVTHLRFQRP-QGFEYKSGQWVRIACL-ALGTTEYHPFTLTSAPHE--DTLSLHIRAAGPWTTRLREIYSA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTGDRCARYPK-------------------------------------LYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFKSSVS-----------------CQVFCKKIYFIWVTRTQRQFEWLADIIREVEEND------HQDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEPFFNSLQEVHPQVRKIGVFSCGPP-GMTKNVEKACQLINRQ--DRTHFSHHYENF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQH2-1", "uniprot_id": "DUOX_DROME", "id": "Q9VQH2-1", "name": "Dual oxidase", "aln": "MSVPSAPHQRAESKNRVPRPGQKNRKLPKLRLHWPGATYGGALLLLLISYGLELGSVHCYEKMYSQTEKQRYDGWYNNLAHPDWGSVDSHLVRKAPPSYSDGVYAMAG-ANRPSTRRLSRLFMRGKDGLGSKFNRTALLAFFGQLVANEIVMASESGCPIEMHRIEIEKCDEMYDRECRGDKYIPFHRAAYDRDTGQSPNAPREQINQMTAWIDGSFIYSTSEAWLNAMRSFHNGTLLTEKDGKLPVRNTMRVPLFNNPVPSVMKMLSPERLFLLGDPRTNQNPAILSFAILFLRWHNTLAQRIKRVHPDWSDEDIYQRARHTVIASLQNVIVYEYLPAFLGTSLPPYEGYKQDIHPGIGHIFQAAAFRFGHTMIPPGIYRRDGQCNFKETP----MGYPAVRLCSTWWD--SSGFFADTSVEEVLMGLASQISEREDPVLCSDVRDKLFGPMEFTRRDLGALNIMRGRDNGLPDYNTARESYGLKRHKTWTDINPPLFETQPELLDMLKEAYDNKLDDVDVYVGGMLESYGQPGEFFTAVIKEQFQRLRDADRFWFENERNGIFTPEEIAELRKITLWDIIVNSTDVKEEEIQKDVFMWRTGDPCPQPMQLNATELEPCTYLEGYDYFSGSELMFIYVCVFLGFVPILCAGAGYCVVKLQNSKRRRLKIRQEALRAPQHKGSVDKMLAREWLHAN-HKRLVTVKFGPEAAIYTVDRKGEKLRTFSLKHIDVVSVEESATNHIKKKPYILLRVPSDHDLVLELESYGARRKFVKKLEDFLLLHKKEMTLMEVNRDIMLARAETRERRQKRLEYFFREAYALTFGLRPGERRRRSDASSDGEVMTVMRTSLSKAEFAAALGMKPNDMFVRKMFNIVDKDQDGRISFQEFLETVVLFSRGKTDDKLRIIFDMCDNDRNGVIDKGELSEMMRSLVEIARTTSLGDDQVTELIDGMFQDVGLEHKNHLTYQDFKLMMKEYKGDFVAIGLDCKG-----------------AKQNFLDTSTNVARMTS---------------------------------------FNIEPMQDK-PRHWLLAKWDAYITFLEENRQNIFYLFLFYVVTIVLFVERFIHYSFMAEHTDLRHIMGVGIAITRGSAASLSFCYSLLLLTMSRNLITKLKEFPIQQYIPLDSHIQFHKIAACTALFFSVLHTVGHIVNFYHVSTQSHENLRCLTREVHF--ASDYKPDITFWLFQTVTGTTGVMLFIIMCIIFVFAHPTIRKKAYNFFWNMHTLYIGLYLLSLIHGLARLTGPPRFWMFFLGPGIVYTLDKIVSLRTKY---MALDVIDTDLLPSDVIKIKFYRP-PNLKYLSGQWVRLSCT-AFRPHEMHSFTLTSAPHE--NFLSCHIKAQGPWTWKLRNYFD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PCNYNPEDQPK-------------------------------------IRIEGPFGGGNQDWYKFEVAVMVGGGIGVTPYASILNDLVFGTSTNR---------------YSGVACKKVYFLWICPSHKHFEWFIDVLRDVEKKD------VTNVLEIHIFITQFFHKFDLRTTMLYICENHFQRLSKTSIFTGLKAVNHFGRPDMSSFLKFVQKKHSYVSKIGVFSCGPR-PLTKSVMSACDEVNKTR-KLPYFIHHFENFG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08908-1", "uniprot_id": "FRE5_YEAST", "id": "Q08908-1", "name": "Ferric reductase transmembrane component 5", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLFARLVLLLVYLAPGSLAKPASTKKRTQWDQIAIDACAKELESHKFDTDVKGRHATLCTYEPALGSWLHCAKDVLDSRKKSKKIFEKTFSKINQYCHDYHKDEVVSNEEYYRIFANASLFIRPLDEVKENIRYPVTPNKASLDR------------------------------------------------------------------------------------------------WVWAYFGPLDNIDKGNVYGVTICLYWIGVLFIAAVYHFLNFSRLKQTVFKNKVSAFLRGHYVLPALVHNHAMSVG--------------------------------------------------------------------------------------------------------------------------------RWFFIGLVPTRLETLVLFGYVLLHGFLLSSYNFDHNELLSDRRSQVLIFLSDRAGILAFAHFPLIVLFGGKNSTMTWLTGIR----YTAFITYHKWLGRFMLVDCTIHAIG-----YTYHAYIENYWKYVKYSDLWTSGRHAMIIVG----------------ILVFFSFFFFRRHYYELFVIT--------HIILAIGFFHACWKHCYKLGWGEWIMACALFWIADRILRLIKIA--IFGMPWAKLKLCGESMIEVRISKSSKWWKAEPGQYIYLYFLRPKIFWQSHPFTVMDSLVE-DGELVVVITVKNGLTKKLQEYLLE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEGYTEMR-------------------------------------VLAEGPYGQSTR-THLFESLLFIAGGAGVPGPLSMAIKAGRQVKSN-------------------DSHQMIKFVWSVRNLDLLEVYRKEIMVLKELNIDTK---IYFTGERKDESNTEEG---------AIANMSTEGRLLTTSKSAEMITDFGRPNIDEIIEEAVSGA---KSLLVTCCGSEGFVDKTRELTAKRVLEHGDKWIEYVEEFQNW-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : :: . : .: : . : : : *::: : : *.**: . : : : . * : . :**:* : :. * *:. :: : * * : . : :. . : . *** . :. : * **. : . . : : : ", "identical_positions": 18, "similar_positions": 58, "identity": "0.92%" }, { "cls_id": "homologset.agr.SGD:S000005913", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q923I8-1", "uniprot_id": "CRY2_RAT", "id": "Q923I8-1", "name": "Cryptochrome-2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAAVVAATVPVQSMGADGASSVHWFRKGLRLHDNPAL------LAAVRGAR---CVRCVYILDPWFAASSSVGINRWRFLLQSLEDLDTSLRKLN---SRLFVVRGQP--ADVFPRLFKEWGVTRLTFEYDSEPFGKE-RDAAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPVGAVSSQHMEN-CRAEIQENHDDTYG-VPSLEELGFPTEGLGPAV---WQGGETEALVRLDK--HLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYRKVKR-------NSTPPLSLFGQLLWREFFYTAATNNPRFDR-MEGNPICIQIPWDR-NPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFH--CYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAANCIIGVDYPRPIVNHAETSRLN----IERMKQIYQQLSRYRGLCLWASVPSCVED----LSHPVAEPGS------------------------SQ---------------AGSISN-TGPRPLSSGPASPKRKLEAAEEPPGEELS--KRARVTVTQMPAQEPPSKDS--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R194-1", "uniprot_id": "CRY2_MOUSE", "id": "Q9R194-1", "name": "Cryptochrome-2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAAVVAATVPAQSMGADGASSVHWFRKGLRLHDNPAL------LAAVRGAR---CVRCVYILDPWFAASSSVGINRWRFLLQSLEDLDTSLRKLN---SRLFVVRGQP--ADVFPRLFKEWGVTRLTFEYDSEPFGKE-RDAAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMES-CRAEIQENHDDTYG-VPSLEELGFPTEGLGPAV---WQGGETEALARLDK--HLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKR-------NSTPPLSLFGQLLWREFFYTAATNNPRFDR-MEGNPICIQIPWDR-NPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFH--CYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAETSRLN----IERMKQIYQQLSRYRGLCLLASVPSCVED----LSHPVAEPGS------------------------SQ---------------AGSISN-TGPRALSSGPASPKRKLEAAEEPPGEELT--KRAR--VTEMPTQEPASKDS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q49AN0-1", "uniprot_id": "CRY2_HUMAN", "id": "Q49AN0-1", "name": "Cryptochrome-2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MAATVATAAAVAPAPAPGTDSASSVHWFRKGLRLHDNPAL------LAAVRGAR---CVRCVYILDPWFAASSSVGINRWRFLLQSLEDLDTSLRKLN---SRLFVVRGQP--ADVFPRLFKEWGVTRLTFEYDSEPFGKE-RDAAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQAIISRMELPKKPVGLVTSQQMES-CRAEIQENHDETYG-VPSLEELGFPTEGLGPAV---WQGGETEALARLDK--HLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKR-------NSTPPLSLFGQLLWREFFYTAATNNPRFDR-MEGNPICIQIPWDR-NPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFH--CYCPVGFGRRTDPSGDYIRRYLPKLKAFPSRYIYEPWNAPESIQKAAKCIIGVDYPRPIVNHAETSRLN----IERMKQIYQQLSRYRGLCLLASVPSCVED----LSHPVAEPSS------------------------SQ---------------AGSMSS-AGPRPLPSGPASPKRKLEAAEEPPGEELS--KRAR--VAELPTPELPSKDA--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97784-1", "uniprot_id": "CRY1_MOUSE", "id": "P97784-1", "name": "Cryptochrome-1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGVN---AVHWFRKGLRLHDNPAL------KECIQGAD---TIRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDANLRKLN---SRLFVIRGQP--ADVFPRLFKEWNITKLSIEYDSEPFGKE-RDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGK-CMTPLSDDHDEKYG-VPSLEELGFDTDGLSSAV---WPGGETEALTRLER--HLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKK-------NSSPPLSLYGQLLWREFFYTAATNNPRFDK-MEGNPICVQIPWDK-NPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFH--CYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLN----IERMKQIYQQLSRYRGLGLLASVPSNSNGNGGLMGYAPGENVPS------------------CSSSGNGGLMGYAPGENVPSCSGGNCSQGSGILHYAHGDSQQTHSLKQGRSSAGTGLSSGKRPSQEEDAQSVGPKVQRQSSN------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q32Q86-1", "uniprot_id": "CRY1_RAT", "id": "Q32Q86-1", "name": "Cryptochrome-1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGVN---AVHWFRKGLRLHDNPAL------KECIQGAD---TIRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDANLRKLN---SRLFVIRGQP--ADVFPRLFKEWNITKLSIEYDSEPFGKE-RDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGK-CTTPLSDDHDEKYG-VPSLEELGFDTDGLSSAV---WPGGETEALTRLER--HLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKK-------NSSPPLSLYGQLLWREFFYTAATNNPRFDK-MEGNPICVQIPWDK-NPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFH--CYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLN----IERMKQIYQQLSRYRGLGLLASVPSNPNGNGGLMGYAPGENVP---------------------SGGSG---------------GGNCSQGSGILHYAHGDSQQTNPLKQGRSSMGTGLSSGKRPSQEEDAQSVGPKVQRQSSN------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16526-1", "uniprot_id": "CRY1_HUMAN", "id": "Q16526-1", "name": "Cryptochrome-1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGVN---AVHWFRKGLRLHDNPAL------KECIQGAD---TIRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDANLRKLN---SRLFVIRGQP--ADVFPRLFKEWNITKLSIEYDSEPFGKE-RDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLISKMEPLEIPVETITSEVIEK-CTTPLSDDHDEKYG-VPSLEELGFDTDGLSSAV---WPGGETEALTRLER--HLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKK-------NSSPPLSLYGQLLWREFFYTAATNNPRFDK-MEGNPICVQIPWDK-NPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFH--CYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLN----IERMKQIYQQLSRYRGLGLLASVPSNPNGNGGFMGYS-AENIP----------------------GCSS---------------SGSCSQGSGILHYAHGDSQQTHLLKQGRSSMGTGLSGGKRPSQEEDTQSIGPKVQRQSTN------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0E8P0-1", "uniprot_id": "Q0E8P0_DROME", "id": "Q0E8P0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSQRSTLVHWFRKGLRLHDNPALSHIFTAANAAPGKY---FVRPIFILDPGILDWMQVGANRWRFLQQTLEDLDNQLRKLN---SRLFVVRGKP--AEVFPRIFKSWRVEMLTFETDIEPYSVT-RDAAVQKLAKAEGVRVETHCSHTIYNPELVIAKNLGKAPITYQKFLGIVEQLKVPKVLGVPEKLKNMPTPPKDEVEQKDSAAYD-CPTMKQLVKRPEELGPNK---FPGGETEALRRMEE--SLKDEIWVARFEKPNTAPNSLEPSTTVLSPYLKFGCLSARLFNQKLKEIIKRQPK-------HSQPPVSLIGQLMWREFYYTVAAAEPNFDR-MLGNVYCMQIPWQE-HPDHLEAWTHGRTGYPFIDAIMRQLRQEGWIHHLARHAVACFLTRGDLWISWEEGQRVFEQLLLDQDWALNAGNWMWLSASAFFHQYFR--VYSPVAFGKKTDPQGHYIRKYVPELSKYPAGCIYEPWKASLVDQRAYGCVLGTDYPHRIVKHEVVHKEN----IKRMGAAYKVNREVR---------------------------------------------------------------------TGKEEE-SSFEEKSETSTSGKRKVRRATGSAP------KRKR------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O77059-1", "uniprot_id": "CRY1_DROME", "id": "O77059-1", "name": "Cryptochrome-1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATRG-ANVIWFRHGLRLHDNPAL------LAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFLLDSLQDIDDQLQAATDGRGRLLVFEGEP--AYIFRRLHEQVRLHRICIEQDCEPIWNE-RDESIRSLCRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARLEDATFVELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINWRGGETQALLLLDERLKVEQHAFERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQLRACVRGVQMTGGAHITGQLIWREYFYTMSVNNPNYDR-MEGNDICLSIPWAKPNENLLQSWRLGQTGFPLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNWMWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSAEQQEQYECLIGVHYPERIIDLSMAVKRN----MLAMKSLRN----------------------------------------------------------------------------------SLITPPPHCRPSNEEEVRQFFWLADVVV-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M3ARS6-1", "uniprot_id": "A0A8M3ARS6_DANRE", "id": "A0A8M3ARS6-1", "name": "", "aln": "MSAGEETKPVSEVRELLRELILGREDPQGFFCMCVSLLGDADTRRLFLDLIKPLSSEYEHLHSQLTSVFLEYFSKDESEELELALTLSLYETKQIDPEDKLHNSDHQHHVPRSYKTYADVRTESSGADGSVVPENQPTAKCTLDTEVHKTRNAIKHINGDKITKSQKRRLRKKQHLLKNPSGPRPVVLWFRRDLRMWDNPALIG-----CLELGAPVIPVFLWNAMEEEGPGVTMSTGGASKYWLHQALVSLKRSLEERG---SHLVTLKAEPSSLTALQGLMDETGAASVVATALYEPWLKE-RDDALWETLEKRGVTCHIYHSYCLRDPYTVSTRGVGLRGIGSVSHFMSCCQQNPAGGLGSPLDAPTTLPSPSAWPQGCPLADLGLARMPRRKDGTVIDWAVDIRKTWDFSEEGAHT------HLEAFLRDGVYRYEKESCRADAPNTSCLSPYLHFGQLSARQVLWAARGARCKSPK--------------FQRKLAWRDLAYWQISLFPDLPW-ESLRPPYKALRWSS-DHAHLKAWQRGRTGYPLVDAAMRQLWQTGWMNNYMRHVVASFLIA-YLHFPWQEGYRWFQDTLVDADVAIDAMMWQNGGMCGLDHWNFV---MHPIDAALTCDPCGTFVRQWCPELKALPDDLIHKPWKCPTSMLRRAGVVFGDSYPERIVIDLEERRAQSLQDVASVRRRFRQFVDQRSGCDLVPVPSRLVQDALGSMEDIVKHEKNGFLLPVITRMEFKHQSEDPDRQDNPYSAVLKGYVSRKRDETVAFLNERDFTASVMCESAQRRERLERDSCLLEGLPRPTASRGGARRTQTRDPYSKVPGGVAVPRK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P05066-1", "uniprot_id": "PHR_YEAST", "id": "P05066-1", "name": "Deoxyribodipyrimidine photo-lyase, mitochondrial", "aln": "-------------------------------------------------------------------------------------------------------------MKRTVISSSNAYASKRSRLDIEHDFEQYHSLNKKYYPRPITRTGANQFNNKSRAKPMEIVEKLQKKQKTSFENVSTVMHWFRNDLRLYDNVGLYKSVALFQQLRQKNAKAKLYAVYVINEDDWRAHMDSGWKLMFIMGALKNLQQSLAELHIP-LLLWEFHTPKSTLSNSKEFVEFFKEKCMNVSSGTGTIITANIEYQTDELYRDIRLLENEDHRLQLKYYHDSCIVAPGLITTDRGTNYSVFTPWYKKWVLYVNNYKKSTSEICHLHIIEPLKYNETFELKPFQYSLPDEFLQYIPKSKWCLPDVSEEAALSR---LKDFLGTKSSKYNNEKDMLYLGGTSGLSVYITTGRISTRLIVNQAFQSCNGQIMSKALK--DNSSTQNFIKEVAWRDFYRHCMCNWPYTSMGMPYRLDTLDIKWEN-NPVAFEKWCTGNTGIPIVDAIMRKLLYTGYINNRSRMITASFLSK-NLLIDWRWGERWFMKHLIDGDSSSNVGGWGFCSSTGIDAQPYFR-VFNMDIQAKKYDPQMIFVKQWVPELISSENKRPEN-------------------YPKPLVDLKHSRERA----LKVYKDAM----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ***..**: ** .* . : : . :: * .:. .* * .. : . : . : . : : . : : :: . ... :* :: * :* * . : :: **: * . : * . : * *.** * :*. * :* *:::: * .* ** * *. * : * . *:* * : . * . .: . ** ::::: * * . **. :: . : ", "identical_positions": 46, "similar_positions": 77, "identity": "5.42%" }, { "cls_id": "homologset.agr.SGD:S000005920", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15429-1", "uniprot_id": "ENOB_RAT", "id": "P15429-1", "name": "Beta-enolase", "aln": "-------------------------------------------------------------------MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPD--LVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSP-DDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKAVFAGRKFRNPKAK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21550-1", "uniprot_id": "ENOB_MOUSE", "id": "P21550-1", "name": "Beta-enolase", "aln": "-------------------------------------------------------------------MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKARYLGKGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPD--LVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSP-DDPARHISGEKLGELYKNFIQNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKAVFAGRKFRNPKAK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13929-1", "uniprot_id": "ENOB_HUMAN", "id": "P13929-1", "name": "Beta-enolase", "aln": "-------------------------------------------------------------------MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGKGVLKAVENINNTLGPALLQKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPD--LILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSP-DDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKAIFAGRKFRNPKAK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17183-1", "uniprot_id": "ENOG_MOUSE", "id": "P17183-1", "name": "Gamma-enolase", "aln": "-------------------------------------------------------------------MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSRIAPALISSGISVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERDLPLYRHIAQLAGNSD--LILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKMVIGMDVAASEFYRDGKYDLDFKSP-ADPSRYITGDQLGALYQDFVRNYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09104-1", "uniprot_id": "ENOG_HUMAN", "id": "P09104-1", "name": "Gamma-enolase", "aln": "-------------------------------------------------------------------MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAGNSD--LILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSP-TDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04764-1", "uniprot_id": "ENOA_RAT", "id": "P04764-1", "name": "Alpha-enolase", "aln": "-------------------------------------------------------------------MSILKIHAREIFDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDNDKTRFMGKGVSKAVEHINKTIAPALVSKKLNVVEQEKIDQLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNPE--VILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKSAIAKAGYTDQVVIGMDVAASEFYRAGKYDLDFKSP-DDASRYITPDQLADLYKSFIKDYPVVSIEDPFDQDDWDAWQKFTATAGIQVVGDDLTVTNPKRIAKAAGEKSCNCLLLKVNQIGSVTESLQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGSKAKFAGRSFRNPLAK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5YC61-1", "uniprot_id": "A0A8I5YC61_RAT", "id": "A0A8I5YC61-1", "name": "phosphopyruvate hydratase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MLFPVGESKKLNVVEQEKIDQLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNPE--VILPVPAFNVINGGSHAGHKLAMQEFMILPVGASSFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNNLENKDALELLKSAIAKAGSTDQVVIGMDVAASEFYRAGKYDLDFKSP-DDASWYITPDQLADLYKSFIKDYPVVSIEDPFDQDDWD------------VVGDDLTVTSPKRIAKAAGEKSCNCLLLKVNQIGSVTESLQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGSKAKFAGRSFRNPLAK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06733-1", "uniprot_id": "ENOA_HUMAN", "id": "P06733-1", "name": "Alpha-enolase", "aln": "-------------------------------------------------------------------MSILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKGVSKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNSE--VILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYTDKVVIGMDVAASEFFRSGKYDLDFKSP-DDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDDWGAWQKFTASAGIQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACKLAQANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKAKFAGRNFRNPLAK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q1X2-1", "uniprot_id": "A0A2R8Q1X2_DANRE", "id": "A0A2R8Q1X2-1", "name": "phosphopyruvate hydratase", "aln": "-------------------------------------------------------------------MSILKIHAREIFDSRGNPTVEVDLYTKKGLFRAAVPSGASTGIYEALELRDNDKTRYLGKGVKRAVKYVNEFLAPALCNQNVSVLEQEKIDKLMLDMDGTDNKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPE--VILPVPAFNVINGGSHAGNKLAMQEFMILPVGASNFKEAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKNAISKAGYTDKIVIGMDVAASEFYKGGKYDLDFKSP-DDPSRYISPDKLADLYKSFVKDYPVVSIEDPFDQDDWEAWTNFTATTNIQVVGDDLTVTNPKRIAKAVSDKACNCLLLKVNQIGSVTESLQACKMAQTNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGDKARFAGKNFRKPI--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15007-1", "uniprot_id": "ENO_DROME", "id": "P15007-1", "name": "Enolase", "aln": "MSWTASVFLRTSTTSMKFLRLRWPLPRIPQNKSANVAPRFRSKSAVSQLSSGFKFVQIRKSTCDSNEMTIKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDNDKANYHGKSVLKAVGHVNDTLGPELIKANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAKAGAAKKGVPLYKHIADLAGNKE--IILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAMKMGSEVYHHLKNVIKAKFGLDATAVGDEGGFAPNIQSNKEALNLISDAIAKAGYTGKIEIGMDVAASEFYKDGQYDLDFKNEKSDKSQWLPADKLANLYQEFIKDFPIVSIEDPFDQDHWEAWSNLTGCTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGTVTESIAAHLLAKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEIGAGVKFAGKSFRKPQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX10-1", "uniprot_id": "ERR1_YEAST", "id": "P0CX10-1", "name": "Enolase-related protein 1", "aln": "-------------------------------------------------------------------MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSELCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVEAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . : * :* :*::*:.:***.***::**********.*.:*.*.:: :.**::**:**. : .::*** ***:***:*** .****** * *.** .* :**::*:**** ** : * ::* .* ******.**: .:.*::: ** .* :: :*:* *.* *:: *:***:**. * : :. :*. *:.:::.:*::*:***: :*.* ::.**** *. .** * .*..* ****:****::**:: * * ***.*:*********.**.****** ****:** .*********:::**** :* :**: *:. ", "identical_positions": 164, "similar_positions": 107, "identity": "32.54%" }, { "cls_id": "homologset.agr.SGD:S000005922", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M939-1", "uniprot_id": "HAT1_RAT", "id": "Q5M939-1", "name": "Histone acetyltransferase type B catalytic subunit", "aln": "MAGFGAMEKFLVEYKSAVEKKLAEYKCNTNTAIELKLVRFPEDLENDIRTFFPEYTHQLFGDDETAFGYKGLKILLYYIAGSLSTMFRVEYASKVDEN-FDCVEADDVEGKIRQIIPPG-FCTNTNDFLSLLEKEADFKPFGTLLHTYSVPSPTGGENFTFQIYKADMTCRGFREYHERLQTFLMWFIETASFIDVDDERWHYFLVFEKY-NKDGATLFATVGYMTVYNYYVYP----------DKTRPRVSQMLILTPFQGQGHGAQLLETVHRYYIASSSVLDITAEDPSKSYVKLRDFVLVKLCQDLPCFSRERLLQGFNEDMAIQAQQKFKINKQHARRVYEILRLLVTDMSDAEQCRSYRLDIKRRLISPYKKKQTDLAKMRKCLRPEELTNQMNQIEISVQHEQLEEQFQELVEDYRRVIERLAQE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14929-1", "uniprot_id": "HAT1_HUMAN", "id": "O14929-1", "name": "Histone acetyltransferase type B catalytic subunit", "aln": "MAGFGAMEKFLVEYKSAVEKKLAEYKCNTNTAIELKLVRFPEDLENDIRTFFPEYTHQLFGDDETAFGYKGLKILLYYIAGSLSTMFRVEYASKVDEN-FDCVEADDVEGKIRQIIPPG-FCTNTNDFLSLLEKEVDFKPFGTLLHTYSVLSPTGGENFTFQIYKADMTCRGFREYHERLQTFLMWFIETASFIDVDDERWHYFLVFEKY-NKDGATLFATVGYMTVYNYYVYP----------DKTRPRVSQMLILTPFQGQGHGAQLLETVHRYYTEFPTVLDITAEDPSKSYVKLRDFVLVKLCQDLPCFSREKLMQGFNEDMVIEAQQKFKINKQHARRVYEILRLLVTDMSDAEQYRSYRLDIKRRLISPYKKKQRDLAKMRKCLRPEELTNQMNQIEISMQHEQLEESFQELVEDYRRVIERLAQE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BY71-1", "uniprot_id": "HAT1_MOUSE", "id": "Q8BY71-1", "name": "Histone acetyltransferase type B catalytic subunit", "aln": "---MAALEKFLVEYKSAVEKKLAEYKCNTNTAIELKLVRFPEDLENDIRTFFPEYTHQLFGDDETAFGYKGLKILLYYIAGSLSTLFRVEYSSKVDEN-FDCVEADDVEGKIRQIIPPG-FCTNTNDFLSLLEKETNFKPFGTLLHTYTVPSQTGGETFTFQIHKADMTCRGFREYHERLQTFLMWFIETASFIDVDDERWHYFLVFEKY-NKDGATLFATVGYMTVYNYYVYP----------DKTRPRVSQMLILTPFQGQGHGAQLLETVHRYYISFPTVLDITAEDPSRSYLKLRDFVLVKFCQFLPSFSRERLLQGFSEDMAIQAQQMFKINKQHARRVYEILRLLVTDMSDAEQYRSYRLDIKRRLISPYKKKQRDLAKMKKCLRPEELTNQMNQIEISVQHEQLEERFQELVEDYRRVIERLAQE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q0KIB3-1", "uniprot_id": "Q0KIB3_DROME", "id": "Q0KIB3-1", "name": "Histone acetyltransferase type B catalytic subunit", "aln": "---------------MAQIEKYQDFVIDALEVVDFKLIRDKADINNDALTFHPAMAHQIFGETETIFGYQDLHVRVMYTAGPLHIYLGVDYGKRVNEISGGEIKADDVVSTIAQSLPDGCYFINLDEFLKTLDKADKFQPFGEKISEYRRVSDDGSERL-FEIYQCEYKSSSFLKFFARLQTFILWFVDAASYIDTDDPQWCYFLSYEKYKNNDGQWQYATAGYTTVYEYYAYP----------QNKRPRISQMLILPPFQKLGLATQLVESIYRFYQSQKNVVDITVEDPSEDFQRLRNFVDARSCMKLKSFAPGEIVKGFNKEMVREAREALKLNPLQVRKVYELLRLFYTNVKDEKEYRPYRLEVKKRLNAVYYKQLKDLKKMERFKMDTEMLRAR-LPTVQQRMEQLHEEYRVVEQEYQSTIAKLRAS--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12341-1", "uniprot_id": "HAT1_YEAST", "id": "Q12341-1", "name": "Histone acetyltransferase type B catalytic subunit", "aln": "--------------MSANDFKPETWTSSANEALRVSIVG------ENAVQFSPLFTYPIYGDSEKIYGYKDLIIHLAFDSVTFKPYVNVKYSAKLGDD-----NIVDVEKKLLSFLPKD--DVIVRDEAKWVDCFAEERKTHNLSDVFEKVSEYSLNGEEFVVYKSSLVDDFARRMHRRVQIFSLLFIEAANYIDETDPSWQIYWLLNKK-------TKELIGFVTTYKYWHYLGAKSFDEDIDKKFRAKISQFLIFPPYQNKGHGSCLYEAIIQSWLEDKSITEITVEDPNEAFDDLRDRNDIQRLRKLGYDAVFQKHSDLSDEFLESSRKSLKLEERQFNRLVEMLLLLNNSP-------SFELKVKNRLYIKN-------------------YDALDQTDPEKAREALQNSFILVKDDYRRIIESINKSQG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : .: .: ..:: :: * * :: ::*: *. :**:.* : : : : .: . *.*. ::.: : ** .: . :* . : . :: . : : * . : * :::.. . . *:* * : *:::*.:** * * : :* *: *.*:*: * .: *.::**:**:.*:* * .: * *:: : : .: :**.***.. : **: : * : . ..:..:: .::: :*:: : .:: *:* *: .. .:.*.:*.** . * *.: : : ::*: * : . ", "identical_positions": 61, "similar_positions": 132, "identity": "14.06%" }, { "cls_id": "homologset.agr.SGD:S000005923", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RK19-1", "uniprot_id": "SNF8_RAT", "id": "Q5RK19-1", "name": "Vacuolar-sorting protein SNF8", "aln": "MHRRGVGAGAIAKKKLAEAKYKERGTVLAEDQLAQMSKQLDMFKTNLEEFASKHKQEIRKNPEFRVQFQDMCATIGVDPLASGKGFWSEMLGVGDFYYELGVQIIEVCLALKHRNGGLITLEELHQQVLKGRGK--FAQDVSQDDLIRAIKKLKALGTGFGIIPVG-GTYLIQSVPAELNMDHTVVLQLAE--KNGYVTVSEIKASLKWETERARQVLEHLLKEGLAWLDLQAPGEAHYWLPALFTDLYSQEISAEEAKEVFP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CZ28-1", "uniprot_id": "SNF8_MOUSE", "id": "Q9CZ28-1", "name": "Vacuolar-sorting protein SNF8", "aln": "MHRRGVGAGAIAKKKLAEAKYKERGTVLAEDQLAQMSKQLDMFKTNLEEFASKHKQEIRKNPEFRVQFQDMCATIGVDPLASGKGFWSEMLGVGDFYYELGVQIIEVCLALKHRNGGLITLEELHQQVLKGRGK--FAQDVSQDDLIRAIKKLKALGTGFGIIPVG-GTYLIQSVPAELNMDHTVVLQLAE--KNGYVTVSEIKTSLKWETERARQVLEHLLKEGLAWLDLQAPGEAHYWLPALFTDLYSQEISAEEAKEAFP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96H20-1", "uniprot_id": "SNF8_HUMAN", "id": "Q96H20-1", "name": "Vacuolar-sorting protein SNF8", "aln": "MHRRGVGAGAIAKKKLAEAKYKERGTVLAEDQLAQMSKQLDMFKTNLEEFASKHKQEIRKNPEFRVQFQDMCATIGVDPLASGKGFWSEMLGVGDFYYELGVQIIEVCLALKHRNGGLITLEELHQQVLKGRGK--FAQDVSQDDLIRAIKKLKALGTGFGIIPVG-GTYLIQSVPAELNMDHTVVLQLAE--KNGYVTVSEIKASLKWETERARQVLEHLLKEGLAWLDLQAPGEAHYWLPALFTDLYSQEITAEEAREALP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5U3V9-1", "uniprot_id": "SNF8_DANRE", "id": "Q5U3V9-1", "name": "Vacuolar-sorting protein SNF8", "aln": "MHRRGVGAGAIAKKKLAEAKYKERGSVLAEDQIAQMSKQLDTFKTHLEEFASKHKQEIRKSSQFRVQFQEMCATIGVDPLASGKGFWSEMLGVGDFYYELGVQIIEVCLALKHRNGGLITLDELHHRVLKGRGK--FAQDVSQDDLVRAIKKLKAMGNGFGMIPVG-GTYLVQSVPAELNMDHTVVLQLAE--KKGYVTVSEIRESLKWEKERACHVLDHLLKEGLAWLDSQAAGEPQYWLPALFSELLSQDVTPEEANQMTP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VD72-1", "uniprot_id": "Q9VD72_DROME", "id": "Q9VD72-1", "name": "Vacuolar-sorting protein SNF8", "aln": "MRRR-VGLGAIQQQKLAAEKYKDKGTDLQENQLEQMTKQMEVFRVKLEEFAMKHKEDIRKNSQFRKQFQEMCAAIGVDPLATGKGFWS-VLGMGDFYYELGVQVVEVCLAANHKTGGLMELDDLRRRLIAARGQSSVHQEITKEDILMAAKKLSIFGNGFVVHKLGKGKYIVQSIPGELSMEETNILNAASNTEQGCVTQSQLIKDLGWTDYRAQQSLDKVLGEGLCWIDKQAGDEPAYWFPSLFPGRNAQTTAAT-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12483-1", "uniprot_id": "SNF8_YEAST", "id": "Q12483-1", "name": "Vacuolar-sorting protein SNF8", "aln": "----MKQFGLAAFDELKDGKYNDVNKTILEKQSVELRDQLMVFQERLVEFAKKHNSELQASPEFRSKFMHMCSSIGIDPLSLFD-RDKHLFTVNDFYYEVCLKVIEICRQTKDMNGGVISFQELEKVHFR-------KLNVGLDDLEKSIDMLKSLEC-FEIFQIR-GKKFLRSVPNELTSDQTKILEICS--ILGYSSISLLKANLGWEAVRSKSALDEMVANGLLWIDYQGGAEALYWDPSWITRQL--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .:* **:: .. : *.* :: .*: *: .* *** **:.::: ..:** :* .**::**:***: . . :: :.*****: ::::*:* :. .**:: :::*.: : :: :*: : . *. : * : : *. :::*:* **. :.* :*: .. * : * : .* * *: *:.:: :** *:* *. *. ** *: :. ", "identical_positions": 59, "similar_positions": 88, "identity": "22.43%" }, { "cls_id": "homologset.agr.SGD:S000005924", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1A5-1", "uniprot_id": "ULA1_RAT", "id": "Q9Z1A5-1", "name": "NEDD8-activating enzyme E1 regulatory subunit", "aln": "MAQQGKILKEQ-----KYDRQLRLWGDHGQEALESAHVCLIN-ATATGTEILKNLVLPGIGSFTIIDGNQVSGEDVGNNFFLQKCSIGKNRAQAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTIVVATQLLESTLLRLADVLWNSQ----IPLLICRTYGLVGYMRIIIKE-HPVIESHPDNALEDLRLDKPFPELREHFQSYDLDHMEKKDHSHTPWIVIIAKYLAQWYSE--TNGRIPKSYKEKEDFRELIRQGILKNENGAPEDEENFEEAIKNVNTALNTTQIPSSIEDIFNDDRCINIT---KQTPSFWILARALKEFVAKEGQG---NLPVRGTIPDMIADSNKYIKLQNVYREKAKKDAAAVGNHVAKLLQSCGQAPESISEKELKLLCSNSAFLRVVRCRSLAEEYGLHTVNKDEIISSMDNPDNEIVLYLMLRAVDRFHKQHGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYGAAEPHTVAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGMSQTSATFQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VBW6-1", "uniprot_id": "ULA1_MOUSE", "id": "Q8VBW6-1", "name": "NEDD8-activating enzyme E1 regulatory subunit", "aln": "MAQPGKILKEQ-----KYDRQLRLWGDHGQEALESAHVCLIN-ATATGTEILKNLVLPGIGSFTIIDGNLVSGEDAGNNFFLQKSSIGKNRAQAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTIVVATQLLESTLLRLADVLWNSQ----IPLLICRTYGLVGYMRIIIKE-HPVIESHPDNALEDLRLDKPFPELREHLQSYDLDHMEKKDHSHTPWIVIIAKYLAQWYNE--TNGRIPKSYKEKEDFRDLIRQGILKNENGAPEDEENFEEAIKNVNTALNTTQIPSSIEDIFNDDRCINIT---KQTPTFWILARALKEFVAKEGQG---NLPVRGTIPDMIADSNKYIKLQNVYREKAKKDAAAVGNHVAKLLQSVGQAPESISEKELKLLCSNSAFLRVVRCRSLAEEYGLDTVNKDEIISSMDNPDNEIVLYLMLRAVDRFHKQHGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGMSQTSATFQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13564-1", "uniprot_id": "ULA1_HUMAN", "id": "Q13564-1", "name": "NEDD8-activating enzyme E1 regulatory subunit", "aln": "MAQLGKLLKEQ-----KYDRQLRLWGDHGQEALESAHVCLIN-ATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPESTSLRLADVLWNSQ----IPLLICRTYGLVGYMRIIIKE-HPVIESHPDNALEDLRLDKPFPELREHFQSYDLDHMEKKDHSHTPWIVIIAKYLAQWYSE--TNGRIPKTYKEKEDFRDLIRQGILKNENGAPEDEENFEEAIKNVNTALNTTQIPSSIEDIFNDDRCINIT---KQTPSFWILARALKEFVAKEGQG---NLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIGQAPESISEKELKLLCSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIVLYLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGMSQTSATFQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXP2-1", "uniprot_id": "ULA1_DANRE", "id": "Q7SXP2-1", "name": "NEDD8-activating enzyme E1 regulatory subunit", "aln": "MTDP-KTSKEQ-----KYDRQLRLWGDHGQEALENAHVCLIN-ATASGTEILKNLVLPGIGAFTIVDGHKVSGEDVGNNFFLSSSAIGKNRAQAATELLQELNSDVSGNFVEESPDKLLDNDCEFFHRFSLVIAVQLPESTCLRLGAVLWEAG----VPFLVCRTYGLIGYMRLIVKE-HTVVESHPDNALEDLRLDQPFTELKRHVESYDLDNMEKKDHSHTPWIIVVARYLEKWYNE--NNSQLPKNYKEKEAFRQLLREGILKNENGGLEDEENFEEAIKNVNTALNPTKISSGTQDIFNAEQCENIT---SQSSSFWVMAHGVRDFVQNEGNG---NLPVRGSIPDMIADSDKFIKLQNVYRDKAMRDAAVVSKHVEMLLQSVGKTPESISEQEIKLFCKNAAFLRVVRCRSLADEYSVDTFNKDEITSCMDSPDSEMVLYLMLRSVDRFYQQHSRYPGVYNYQVEEDINKLKLCVNSLLQEYSLNVNVKDDYIHEFCRYGAAEPHTVAAFLGGSAAQEAIKIITHQFVPFNNTFLYNAMSQTSATFQL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTE9-1", "uniprot_id": "ULA1_DROME", "id": "Q9VTE9-1", "name": "Nedd8-activating enzyme E1 regulatory subunit", "aln": "MSSPAPKSPELSDKSKKYDRQIRLWGEHGQTLLEAATVCLVN-VTAVGCETAKGLVLPGIGGFTVADGSTVKEEDLGNNFFLDSSYLGKSKALACMQLLQELNPDVNGDYVDESADFLLANRPNFFDSFDLVIASNLNEQTLLLLAERLWELN----VPLIYCRSLGMLGTIRLQIRE-HCIVEAHPDNRQFDLRLEHPFDALREHLDGTEVT-------SKVPWLLVLHKYLNVWQKQQADGTQTPRNYKEKNQLKETIREEMK-------ADEENYEEAIKAVNTAFGAGQVPKSLKAIFEDDACEQLN---KKSNVFWIMAKALKHFVIHENEG---HLPLPGVLPDMTANTDSYIALQHIYRQQALQDADQVYHKCQEYLKQLALPADSIDERSVRLICKEAAGLAVIRGTRIAEEYEKSSRLLP-LVEDNELQGNLTAYNFALRAYERFLSECGNIPG--ECIVEQDIGRLKSIAAKMLSDLGMHATISDDVLHEICRYGGAELHAVSAFIGGCAAQEVIKIITKQYKPIDNTFIYNAITTESVTLKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12059-1", "uniprot_id": "ULA1_YEAST", "id": "Q12059-1", "name": "NEDD8-activating enzyme E1 regulatory subunit", "aln": "--------------MERYDRQLRLWGALGQDSLNRSRVCVVGPATPLLQEVFKNLVLAGISSLTWLKVECAVQSGS-----LFLAELKKDLEPLASKQLEYEENDLRKTLQQPQYD---------WTRFSVVILTCIGEQTAMLDLNEIRRQRGTKFPPVLNTFVSGFYGYIYLVLSETHFVLQAHPDSKKYDLRLQNPWPELINYVDTFDLSKMDTATFSGIPYTVLLMKCIAKLERD-------GNNGRITIDQMKKVLDQICLPLGNDVIYEPNYVEAKRYAYLACSQNDCCKELEDLLRNLEISDYGNDWHDTYNYEILTLLLTLKNIAKENGELSFQPLTGTLPDMESTTENYIRLKKLYEVKAKLDKSRV-------EESLARSKKIVSQDVLETFCSHYGEVRKILPP------------KSDLLGIFSTSN-------------------------------------ALLDALVMVQFWEQPAVTAEDKDEFIGLRVDDNYSVMAFFGGAVVQEAIKLITHHYVPIDNLFLYNGINNSSATYKI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :****:**** ** *: : **::. .*. * *.***.**..:* . . .. * . : *. . : *: : *: : . : : * :*: : *.* : : . *.: *: * : : : * * ::::***. ****::*: * .:.: :: * *: ::: : : : .. : . . : : : * *: ** : . * . . . : ::. : .: : ::: : : :* *: * :*** : : .:* *:::*. :* * * :. . . . :.: :. :*.. . : : : . . .: : :. : .*: : ::: **:**...**.**:**::: ::* ::*..:. *.* ::", "identical_positions": 79, "similar_positions": 154, "identity": "14.29%" }, { "cls_id": "homologset.agr.SGD:S000005927", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6T3U3-1", "uniprot_id": "NPCL1_RAT", "id": "Q6T3U3-1", "name": "NPC1-like intracellular cholesterol transporter 1", "aln": "-MAAAWLGWLLWALLLSAAQGELYTPKHEAGVCTFYEECGKNPELSGGLTSLSNVSCLSNTPARHVTGEHLALLQRICPRLYN------GPNTTFACCSTKQLLSLESSMSITKALLTRCPACSDNFVSLHCHNTCSPDQSLFINVTRVVERGAGEP----PAVVAYEAFYQRSFAEKAYESCSQVRIPAAASLAVGSMCGVYGSALCNAQRWLNFQGDTGNGLAPLDITFHLLEPGQALPDGIQPLNGKIAPCNESQGDDSAVCSCQDCAASCPVIPPPE---------ALRPSFYMGRMPGWLALIIIFTAVFVLLSAVL-----VRLR-----VVSNRNKNKAEGPQEAPKLPHKHKLSPHTILGRFFQNWGTRVASWPLTVLALSFIVVIALAAG-LTFIELTTDPVELWSAPKSQARKEKSFHDEHFGPFFRTNQIFVTARNRSSYKYDSLLLGSKN-FSGILSLDFLLELLELQERLRHLQVWSPEAERNISLQDICYAPLN--PYNTSLSDCCVNSLLQYFQNNRTLLMLTANQTLNGQTSLVDWKDHFLYCANAPLTFKDGTSLALSCMADYGAPVFPFLAVGG--------YQGTDYSEAEALIITFSLNNYPADDPRMAQAKLWEEAFLKEMESFQRN-TSDKFQVAFSAERSLEDEINRTTIQDLPVFAVSYIIVFLYISLALGSYSRCSRVAVESKATLGLGGVIVVLGAVLAAMGFYSYLGVPSSLVIIQVVPFLVLAVGADNIFIFVLEYQR-LPRMPGEQREAHIGRTLGSVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAIILDFLLQMTAFVALLSLDSKRQEASRPDVLCCFS-TRKLPPPKEKE--------GLLLRFFRKIYAPFLLHRFIRPVVMLLFLTLFGANLYLMCNINVGLDQELALPKDSYLIDYFLFLNRYLEVGPPVYFVTTSGFNFSSEAGMNATCSSAGCKSFSLTQKIQYASEFPDQSYVAIAASSWVDDFIDWLTPSSSCCRLYIRGPHKDEFCPSTDTSFNCLKNCMNRTLGP---VRPTAEQFHKYLPWFLNDPPNIRCPKGGLAAYRTSVNLSS-DGQVIA---------------------------SQFMAYHKPLRNSQDFTEALRASRLLAANITADLRKVP-------GTDPNFEVFPYTISNVFYQQYLTVLPEGIFTLALCFVPTFVVCYLLLGLDMCSGILNLLSIIMILVDTIGLMAVWGISYNAVSLINLVTAVGMSVEFVSHITRSFAVS---TKPTRLERAKDATVFMGSAVFAGVAMTNFPGILILGFAQAQLIQIFFFRLNLLITLLGLLHGLVFLPVVLSYLGPDVNQALVQEEKLASEAAVAPE-PSCPQYPSPADADAN--VNYGFAPELAHGANAARSSLPKSDQKF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6T3U4-1", "uniprot_id": "NPCL1_MOUSE", "id": "Q6T3U4-1", "name": "NPC1-like intracellular cholesterol transporter 1", "aln": "-MAAAWQGWLLWALLLNSAQGELYTPTHKAGFCTFYEECGKNPELSGGLTSLSNISCLSNTPARHVTGDHLALLQRVCPRLYN------GPNDTYACCSTKQLVSLDSSLSITKALLTRCPACSENFVSIHCHNTCSPDQSLFINVTRVVQRDPGQL----PAVVAYEAFYQRSFAEKAYESCSRVRIPAAASLAVGSMCGVYGSALCNAQRWLNFQGDTGNGLAPLDITFHLLEPGQALADGMKPLDGKITPCNESQGEDSAACSCQDCAASCPVIPPPP---------ALRPSFYMGRMPGWLALIIIFTAVFVLLSVVL-----VYLR-----VASNRNKNKTAGSQEAPNLPRKRRFSPHTVLGRFFESWGTRVASWPLTVLALSFIVVIALSVG-LTFIELTTDPVELWSAPKSQARKEKAFHDEHFGPFFRTNQIFVTAKNRSSYKYDSLLLGPKN-FSGILSLDLLQELLELQERLRHLQVWSHEAQRNISLQDICYAPLN--PHNTSLTDCCVNSLLQYFQNNHTLLLLTANQTLNGQTSLVDWKDHFLYCANAPLTYKDGTALALSCIADYGAPVFPFLAVGG--------YQGTDYSEAEALIITFSINNYPADDPRMAHAKLWEEAFLKEMQSFQRS-TADKFQIAFSAERSLEDEINRTTIQDLPVFAISYLIVFLYISLALGSYSRWSRVAVDSKATLGLGGVAVVLGAVVAAMGFYSYLGVPSSLVIIQVVPFLVLAVGADNIFIFVLEYQR-LPRMPGEQREAHIGRTLGSVAPSMLLCSLSEAICFFLGALTSMPAVRTFALTSGLAIIFDFLLQMTAFVALLSLDSKRQEASRPDVVCCFS-SRNLPPPKQKE--------GLLLCFFRKIYTPFLLHRFIRPVVLLLFLVLFGANLYLMCNISVGLDQDLALPKDSYLIDYFLFLNRYLEVGPPVYFDTTSGYNFSTEAGMNAICSSAGCESFSLTQKIQYASEFPNQSYVAIAASSWVDDFIDWLTPSSSCCRIYTRGPHKDEFCPSTDTSFNCLKNCMNRTLGP---VRPTTEQFHKYLPWFLNDTPNIRCPKGGLAAYRTSVNLSS-DGQIIA---------------------------SQFMAYHKPLRNSQDFTEALRASRLLAANITAELRKVP-------GTDPNFEVFPYTISNVFYQQYLTVLPEGIFTLALCFVPTFVVCYLLLGLDIRSGILNLLSIIMILVDTIGLMAVWGISYNAVSLINLVTAVGMSVEFVSHITRSFAVS---TKPTRLERAKDATIFMGSAVFAGVAMTNFPGILILGFAQAQLIQIFFFRLNLLITLLGLLHGLVFLPVVLSYLGPDVNQALVLEEKLATEAAMVSE-PSCPQYPFPADANTSDYVNYGFNPEFIPEINAASSSLPKSDQKF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHC9-1", "uniprot_id": "NPCL1_HUMAN", "id": "Q9UHC9-1", "name": "NPC1-like intracellular cholesterol transporter 1", "aln": "MAEAGLRGWLLWALLLRLAQSEPYTTIHQPGYCAFYDECGKNPELSGSLMTLSNVSCLSNTPARKITGDHLILLQKICPRLYT------GPN-TQACCSAKQLVSLEASLSITKALLTRCPACSDNFVNLHCHNTCSPNQSLFINVTRVAQLGAGQL----PAVVAYEAFYQHSFAEQSYDSCSRVRVPAAATLAVGTMCGVYGSALCNAQRWLNFQGDTGNGLAPLDITFHLLEPGQAVGSGIQPLNEGVARCNESQGDDVATCSCQDCAASCPAIARPQ---------ALDSTFYLGQMPGSLVLIIILCSVFAVVTILL-----VGFR-----VAPARDKSKMVDPKKGTSLSDKLSFSTHTLLGQFFQGWGTWVASWPLTILVLSVIPVVALAAG-LVFTELTTDPVELWSAPNSQARSEKAFHDQHFGPFFRTNQVILTAPNRSSYRYDSLLLGPKN-FSGILDLDLLLELLELQERLRHLQVWSPEAQRNISLQDICYAPLN--PDNTSLYDCCINSLLQYFQNNRTLLLLTANQTLMGQTSQVDWKDHFLYCANAPLTFKDGTALALSCMADYGAPVFPFLAIGG--------YKGKDYSEAEALIMTFSLNNYPAGDPRLAQAKLWEEAFLEEMRAFQRR-MAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIVIFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVVPFLVLSVGADNIFIFVLEYQR-LPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEASRLDVCCCVK-PQELPPPGQGE--------GLLLGFFQKAYAPFLLHWITRGVVLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLDYFLFLNRYFEVGAPVYFVTTLGYNFSSEAGMNAICSSAGCNNFSFTQKIQYATEFPEQSYLAIPASSWVDDFIDWLTP-SSCCRLYISGPNKDKFCPSTVNSLNCLKNCMSITMGS---VRPSVEQFHKYLPWFLNDRPNIKCPKGGLAAYSTSVNLTS-DGQVLDTVAILSPRLEYSGTISAHCNLYLLDSTSRFMAYHKPLKNSQDYTEALRAARELAANITADLRKVP-------GTDPAFEVFPYTITNVFYEQYLTILPEGLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAVSLINLVSAVGMSVEFVSHITRSFAIS---TKPTWLERAKEATISMGSAVFAGVAMTNLPGILVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGPDVNPALALEQKRAEEAVAAVMVASCPNHPSRVSTADNIYVNHSFEGS-IKGAGAISNFLPNNGRQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35604-1", "uniprot_id": "NPC1_MOUSE", "id": "O35604-1", "name": "NPC intracellular cholesterol transporter 1", "aln": "--MGAHHPALG-LLLLLLCPAQVFSQS-----CVWYGECG-------IATGDKRYNCKYSGPPKPLPKDGYDLVQELCPGLF--------FDNVSLCCDIQQLQTLKSNLQLPLQFLSRCPSCFYNLMTLFCELTCSPHQSQFLNVTATEDYFDPKTQENKTNVKELEYFVGQSFANAMYNACRDVEAPSSNEKALGLLCGRD-ARACNATNWIEYMFNKDNGQAPFTIIPVFSDLS---ILGMEPMRNATKGCNESVDEVTGPCSCQDCSIVCGPKPQPPPPPMPWRIWGLDAMYVIMWVTYVAFLFVFFGALLAVWCHRR-----RYFVSEYTPIDSNIAFSVNSSDKGEASCCDPLGAAFDDCLRRMFTKWGAFCVRNPTCIIFFSLAFITVCSSG-LVFVQVTTNPVELWSAPHSQARLEKEYFDKHFGPFFRTEQLIIQAPNTSVHIYEPYPAGADVPFGPPLNKEILHQVLDLQIAIESITAS--YNNETVTLQDICVAPLS--PYN---KNCTIMSVLNYFQNSHAVLDSQVGDDFY---IYADYHTHFLYCVRAPASLNDTSLLHGPCLGTFGGPVFPWLVLGG--------YDDQNYNNATALVITFPVNNYYNDTERLQRAWAWEKEFISFVKNYKN----PNLTISFTAERSIEDELNRESNSDVFTVIISYVVMFLYISLALGHIQSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYMGMPLTLIVIEVIPFLVLAVGVDNIFILVQTYQR-DERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFGALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNHLDILCCVRGADDGQGSHASE--------SYLFRFFKNYFAPLLLKDWLRPIVVAVFVGVLSFSVAVVNKVDIGLDQSLSMPNDSYVIDYFKSLAQYLHSGPPVYFVLEEGYNYSSRKGQNMVCGGMGCDNDSLVQQIFNAAELDTYTRVGFAPSSWIDDYFDWVSPQSSCCRLYN---VTHQFCNASVMDPTCVRCRPLTPEGK---QRPQGKEFMKFLPMFLSDNPNPKCGKGGHAAYGSAVNIVG-DDTYIG--------------------------ATYFMTYHTILKTSADYTDAMKKARLIASNITETMRSK----------GSDYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGSIFLVTLVVLGCELWSAVIMCITIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTMS---TKGSRVSRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFEIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVNKAKR-----------------HTTYERYRGTERERLLNF------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V7K5-1", "uniprot_id": "G3V7K5_RAT", "id": "G3V7K5-1", "name": "", "aln": "--MGAHHPALGLLLLLLLCPAQVFSQS-----CVWYGECG-------VAFGDKRYNCEYSGPPKPLPKDGYDLVQELCPGLF--------FGNVSLCCDVQQLQTLKSNLQLPLQFLSRCPSCFYNLMTLFCELTCSPHQSQFLNVTATEDYFDPETRENKTNVKELEYYVGRSFANAMYNACRDVEAPSSNEKALGLLCGRD-ARACNATNWIEYMFNKDNGQAPFTIIPVFSDLS---VLGMEPMRNATKGCNESVDEVTGPCSCQDCSAVCGPKPQPPPPPVPWRILGLDAMYVIMWVAYMAFLVLFFGGLLAVWCHRR-----RYFVSEYTPIDSNIAFSSNSSDKGEASCCDPLGVAFDDCLRRMFTKWGAFCVRNPTCIIFFSLVFIAACSSG-LVFVQVTTNPVELWSAPHSQARLEKEYFDKHFGPFFRTEQLIIQAPNSSVHIYEPYPSGADVPFGPPLNKEILHQVLDLQIAIESITAS--YNNETVTLQDICVAPLS--PYN---KNCTIMSVLNYFQNSHAVLDNQVGDDFF---VYADYHTHFLYCVRAPASLNDTSLLHGPCLGTFGGPVFPWLVLGG--------YDDQNYNNATALVITFPVNNYYNDTEKLQRAWAWEKEFINFVKNYKN----PNLTISFTAERSIEDELNRESNSDVFTVLISYAVMFLYISLALGHIQSWNRVLVDSKISLGIAGILIVLSSVTCSLGIFSYIGMPLTLIVIEVIPFLVLAVGVDNIFILVQTYQR-DERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFGALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSFLGLDIKRQEKNRLDILCCVRGPDDGQESQASE--------SYLFRFFKNAFAPFLLTDWLRPVVMAVFVGILSFSIAVVNKVEIGLDQSLSMPNDSYVIDYFKSLGQYLHSGPPVYFVLEEGYNYSSRRGQNMVCGGMGCDNDSLVQQIFNAAELDTYTRVGFAPSSWIDDYFDWVSPQSSCCRLYN---VTHQFCNASVIDPTCVRCRPLTPEGK---QRPQGKEFMKFLPMFLSDNPNPKCGKGGHAAYSSAVNIMG-DDTYIG--------------------------ATYFMTYHTILKTSADYIDALKKARLIASNITETMRSK----------GSDYRVFPYSVFYVFYEQYLTIIDDAIFNLSVSLGSIFLVTLVALGCELWSAVIMCLTIAMILVNMFGVMWLWGISLNAVSLVNLVMTCGISVEFCSHITRAFTMS---TKGSRVSRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFEIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVNKAKR-----------------HTTQERYKGTERERLLNF------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15118-1", "uniprot_id": "NPC1_HUMAN", "id": "O15118-1", "name": "NPC intracellular cholesterol transporter 1", "aln": "--MTARGLALG-LLLLLLCPAQVFSQS-----CVWYGECG-------IAYGDKRYNCEYSGPPKPLPKDGYDLVQELCPGFF--------FGNVSLCCDVRQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATEDYVDPVTNQTKTNVKELQYYVGQSFANAMYNACRDVEAPSSNDKALGLLCGKD-ADACNATNWIEYMFNKDNGQAPFTITPVFSDFP---VHGMEPMNNATKGCDESVDEVTAPCSCQDCSIVCGPKPQPPPPPAPWTILGLDAMYVIMWITYMAFLLVFFGAFFAVWCYRK-----RYFVSEYTPIDSNIAFSVNASDKGEASCCDPVSAAFEGCLRRLFTRWGSFCVRNPGCVIFFSLVFITACSSG-LVFVRVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKHIYQPYPSGADVPFGPPLDIQILHQVLDLQIAIENITAS--YDNETVTLQDICLAPLS--PYN---TNCTILSVLNYFQNSHSVLDHKKGDDFF---VYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGG--------YDDQNYNNATALVITFPVNNYYNDTEKLQRAQAWEKEFINFVKNYKN----PNLTISFTAERSIEDELNRESDSDVFTVVISYAIMFLYISLALGHMKSCRRLLVDSKVSLGIAGILIVLSSVACSLGVFSYIGLPLTLIVIEVIPFLVLAVGVDNIFILVQAYQR-DERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLGALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCVRGAEDGTSVQASE--------SCLFRFFKNSYSPLLLKDWMRPIVIAIFVGVLSFSIAVLNKVDIGLDQSLSMPDDSYMVDYFKSISQYLHAGPPVYFVLEEGHDYTSSKGQNMVCGGMGCNNDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRVDN---ITDQFCNASVVDPACVRCRPLTPEGK---QRPQGGDFMRFLPMFLSDNPNPKCGKGGHAAYSSAVNILLGHGTRVG--------------------------ATYFMTYHTVLQTSADFIDALKKARLIASNVTETMGIN----------GSAYRVFPYSVFYVFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCELWSAVIMCATIAMVLVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVS---MKGSRVERAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVNKAKS-----------------CATEERYKGTERERLLNF------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VL24-1", "uniprot_id": "Q9VL24_DROME", "id": "Q9VL24-1", "name": "", "aln": "MSPRSPLRISPFGVHILIAAVLFTLIQSSKQDCVWYGVCN-------TNDFSHSQNCPYNGTAKEMATDGLELLKKRCGFLLENSENK-------FCCDKNQVELLNKNVELAGNILDRCPSCMENLVRHICQFTCSPKQAEFMHVVATQKNKKGDE-----YISSVDLHISTEYINKTYKSCSQVSVPQTGQLAFDLMCGAYSASRCNPTKWFNFMGDATNPYVPFQITYIQHEPKSN-SNNFTPLNVTTVPCNQAVSSKLPACSCSDCDLSCPQGPPEPPRPEPFKIVGLDAYFVIMAAVFLVGVLVFLMGSFLFTQGSSMDDNF---------QVDGNDVSDEMPYSENDSYFEKLGAHTETFLETFFTKWGTYFASNPGLTLIAGASLVVILGYG-INFIEITTDPVKLWASPNSKSRLEREFFDTKFSPFYRLEQIIIKAVNLPQIVHNTS-NGPYT-FGPVFDREFLTKVLDLQEGIKEIN-AN-----GTQLKDICYAPLSDDGSEIDVSQCVVQSIWGYFGDD---RERLDDHDED-NGFNVTYLDALYDCISNPYL----------CLAPYGGPVDPAIALGGFLPPGDQLTGSTKFELANAIILTFLVKNHHNKT-DLENALTWEKKFVEFMTNYTKNNMSQYMDIAFTSERSIEDELNRESQSDVLTILVSYLIMFMYIAISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGVFGYIGLPATLIIVEVIPFLVLAVGVDNIFILVQTHQR-DQRKPNETLEQQVGRILGKVGPSMLLTSLSESFCFFLGGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCFIK--GKKPDSITSN-------EGLLYKFFSSVYVPFLMKKIVRASVMVIFFAWLCFSIAIAPRIDIGLDQELAMPQDSFVLHYFQSLNENLNIGPPVYFVLKGDLAYTNSSDQNLVCAGQYCNDDSVLTQIYLASRHSNQTYIARPASSWIDDYFDWAAAASSCCKYRK---DSGDFCPHQDTS--CLRCN--ITKNSL--LRPEEKEFVKYLPFFLKDNPDDTCAKAGHAAYGGAVRYSNSHERLN-------------------------IEASYFMAYHTILKSSADYFLALESARKISANITQMLQGRLMSNGVPMASALTVEVFPYSVFYVFYEQYLTMWSDTLQSMGISVLSIFVVTFVLMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVEFCSHLVHSFATS---KSVSQIDRAADSLSKMGSSIFSGITLTKFAGILVLAFAKSQIFQVFYFRMYLGIVVIGAAHGLIFLPVLLSYIGAPVSNARL-------------------RYHSQAAAEHETALAGIL----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VRC9-1", "uniprot_id": "NPC1B_DROME", "id": "Q9VRC9-1", "name": "NPC intracellular cholesterol transporter 1 homolog 1b", "aln": "-------MKVIFATIWLIAGAWS--QSAEQLGCIWYGQSH-------MIGAHWVNKGDTNPARPLNSPTSEAIFAKRCPMLYKEYKGESGEDELSLCCDAAQIETMESGLSQADGVFSRCPTCTRNMALTVCAMTCAKNHTLFLTAYN-DTNDAGVD-----YVKYIDYRLTDDTVSKIYNSCIGIQHTQTGRPAMDLGCGSYNAKTCNYRRWYEFMGDVSGDYVPFQINYKWSEDAEE-GSNEIYLDLSPLKCGESYEDSY-ACACIDCEESCPLTDAPTGPDELWKIAGLYG------VTFILALIIACALSFFIFWG---------------------------AFGKTSAPSVCMPTLFGEFFYHGFRIWGTFCAKHPVIVLALCSWAIAGLSFG-IRYMTITTDPVELWAGEESQTRIEKDYFDQHFGPFYRTNQMFVKAVNQTYFTHETS-NGVLN-FGPAFEYNFLKEVFELQDSIMKLGMAD-----NEGLDKICYAPVLMAGETPTVDRCAIQSVYGYFQHD---MDRFENSYVDSNNYTINYLNQLEDCLRVPMME--------DCFGTFGGPIEPGIAVGG--MPKVAVGEDPDYMLATGLVLTFLGRNYNDES-KLEPNMKWEKLFVDFLRDYK----SDRLDIAYMAERSIQDAIVELSEGEVSTVVISYVVMFVYVAIALGHIRSCRGFLRESRIMLAIGGIVIVLASVVCSLGFWGYLDVTTTMLAIEVIPFLVLAVGVDNIFIMVHTYQR-LDHSKFKTTHEAIGEAIGQVGPSILQTAGSEMACFAIGCISDMPAVKTFAMYAAIAILLDFLLQITAFVALMAIDEKRYLDGRLDMLCCVKSGGKKINDEDGDGVDRPKEVGLLETLFKNFYSPFLLSKPVKVSVLLIFTVITCLSLMVTPSIEKGLDQEMSMPKNSHVVKYFRYMVDLLAMGAPVYWVLKPGLNYSEPLQQNLICGGVECNNNSLSVQLYTQAQYPEITSLARPASSWLDDYIDWLAIS-DCCKYNV---TTGGFCSSNSKSEDCLPCERGFTENG---LRPDAETFNKYIPYFLFDLPDAECAKAGRASYADAVIYTIDDVGMST------------------------VQDSYFMQYSTTSTTSEEFYSQLREVRRISGEINAMFK----------ENNVDAEIFAYCVFYIYYEQYLTIWGDAMFSLGMSLVAIFLVTLLITGLDITSTFIVLFMVICILINMLGMMWAWSINLNAISLVNLVVCVGIGVEFVAHIVRSFKRA---EGTAQ-ERARHSLNVTGSSVLSGITLTKFAGIVVLGFSNSQIFQVFYFRMYLGIVLIGAAHGLILLPVLLSLLGPPQKLARS-------------------SGAEPTASITITTN--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12200-1", "uniprot_id": "NPC1_YEAST", "id": "Q12200-1", "name": "NPC intracellular sterol transporter 1-related protein 1", "aln": "----------MNVLWIIALVGQLMRLVQGTATCAMYGNCGKKS----VFGNELPCPVPRSFEPPVLSDETSKLLVEVCGEEWK--------EVRYACCTKDQVVALRDNLQKAQPLISSCPACLKNFNNLFCHFTCAADQGRFVNITKVEKSKEDKD-----IVAELDVFMNSSWASEFYDSCKNIKFSATNGYAMDLIGGGA----KNYSQFLKFLGDAKPMLGGSPFQINYKYDLANEEKEWQEFNDEVYACDDAQ----YKCACSDCQESCPHLKPLKDG--VCKVGPLPCFSLSVLIFYTICALFAFMWYYLCKRKKN-------GAMIVDDDIVPESGSLDESETNVFESFNNETNFFNGKLANLFTKVGQFSVENPYKILITTVFSIFVFSFIIFQYATLETDPINLWVSKNSEKFKEKEYFDDNFGPFYRTEQIFVVNET-----------------GPVLSYETLHWWFDVENFITEELQSS----ENIGYQDLCFRPTED-------STCVIESFTQYFQGALP--------------NKDSWKRELQECGKFPVN----------CLPTFQQPLKTNLLFSD-----------DDILNAHAFVVTLLLTNH------TQSANRWEERLEEYLLDLKVP---EGLRISFNTEISLEKELN--NNNDISTVAISYLMMFLYATWALRRKD------GKTRLLLGISGLLIVLASIVCAAGFLTLFGLKSTLIIAEVIPFLILAIGIDNIFLITHEYDRNCEQKPEYSIDQKIISAIGRMSPSILMSLLCQTGCFLIAAFVTMPAVHNFAIYSTVSVIFNGVLQLTAYVSILSLYEKRSN------------YKQITGNEETK-----------ESFLKTFYFKMLTQKRL---IIIIFSAWFFTSLVFLPEIQFGLDQTLAVPQDSYLVDYFKDVYSFLNVGPPVYMVVKN-LDLTKRQNQQKICGKFTTCERDSLANVLEQERHR--STITEPLANWLDDYFMFLNPQNDQCCRLKKG--TDEVCPPSFPSRRCETCFQQGSWNYNMSGFPEGKDFMEYLSIWIN-APSDPCPLGGRAPYSTALVYNETSVSASV-----------------------------FRTAHHPLRSQKDFIQAYSDGVRISS------------------SFPELDMFAYSPFYIFFVQYQTLGPLTLKLIGSAIILIFFISSVFL-QNIRSSFLLALVVTMIIVDIGALMALLGISLNAVSLVNLIICVGLGVEFCVHIVRSFTVVPSETKKDANSRVLYSLNTIGESVIKGITLTKFIGVCVLAFAQSKIFDVFYFRMWFTLIIVAALHALLFLPALLSLFGGESYRDDS------------------------IEAED------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * . . . :. . * ** *: : .:. . .: **:* *: * **: : *: : : . . *.:* : . : *.. * * .: :: : : : *.:: *:* ** * * .. : * * . * : : . : : : *:*:.** . *: *: :.* :*.**:* :*::: . :. : * :::: : ..:* * * : *. ** : : * * *: : *: . : ... . * .:::*: *: **: : . : : ::: :* *::. : . :: . ** ::*:* : :* .:: *.:.*: :**.:: .: *. :.: ::: :*:***:*::* ****::. ::* : . : :* :.*::: .: .* :. : ****: *:: : :::::: :**::.:*::: : ** . . :: . : :* :: :* .: :. **** :::*.:*.::.** : : *.*** : : *. . . :: . : : . :.*:**:: : . * . .* . * . . * * .::. :: *. * .* *.* :: * .. :: ::. :*.* ::: ** *: : :. .. * : : :: * .: : :::: ..* .*. **:**:**: *:.*** *:.::* .*. : *.::: *:::*:: *: :*.:::::::::*:**: : : ::. *.*::**.:** .* : ", "identical_positions": 159, "similar_positions": 323, "identity": "11.13%" }, { "cls_id": "homologset.agr.SGD:S000005929", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LEZ3-1", "uniprot_id": "A0ABK0LEZ3_RAT", "id": "A0ABK0LEZ3-1", "name": "ATP-dependent DNA helicase DDX11", "aln": "------MAEESQEMGGIHFPFP-FPPYP------------IQKDFMAELYKVLEAGK-IGIFESPTGTGKSLSLICGALSWLRDFEQKKLQAEAGLLAPASGPTSSGRN-SVLSSSSCQEPSDTLRPAGDPDWVTEFVQKKEERDLVERLREEQLRRRKREE-RLQEVCQDGRRRFAAKRSRQEEEETETLLRLSREMLAADTAPEQLGQLECGEEHLVLAEYESDEER-RGSR--------ADEGEDDLEEEHITKIYYCSRTHSQLAQFVREVQKSPFG---------KETRLVSLGSRQSLCVNEDVKSLGSVHLMNDRCVDMQRRKH-KKMRIGEDKPKRRRQKMQASCPFYNHEQMELLRDEILLEVKDMEQLVALGKEAQACPYYGSRFAIPAAQLVVLPYPMLLHAATRQAAGIRLQGQVVIIDEAHNLIDTITNIHSTEVNGSQLCQAHSQLLQYMERYRKRLKAKNLMYIKQILYLLDKFVAVLGGNVKQNPSTQSLPQTGSELQSINDFLFQSQVDNINLFKVQRYLEKSMLSRKLFGFTECF---------------GVVLPSLSDSEENRGLGGFQQFLKSLQSGPPE---DSLEEGQAVALR-----PASPLMHIEAFLEALTTANQDGRVIVNRQGSVGQSSLKFLLLNPAVHFAQVVKECRALVIAGGTMQPALRSQGLMSLLQVSDFREQLLACSGVEASRVVEFSCGHVIPPDNILPLIICSGPSNQQLEFTYQRRELPQMME-ETGRILCNLCNVVP--GGMVCFLPSYEYLRQVHAHWDKTGLLARLSVRKKIFQEPKRASQVEQVLTAYSTCIASCSHSEGHLTGALLLSVVGGKMSEGINFSDDLGRCVVMVGMPYPNIKSPELQEKMAYLDQTIPRTHG---------QPPPGTVLIENLCMKAIN-----QSIGRAIRHQKDFASIVLLDHR--------YARPSILAKLP--------------AWIRDR---VEVKATFGPAFAAMRK-------------------------FHREKSHPCLGFVVNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6AXC6-1", "uniprot_id": "DDX11_MOUSE", "id": "Q6AXC6-1", "name": "ATP-dependent DNA helicase DDX11", "aln": "------MADENQEIGGIHFPFP-FPPYP------------IQKDFMAELYKVLEGGK-IGIFESPTGTGKSLSLICGALSWLRDFEKKKLQAEALLLAPGSGPPSSEKN-SLLTSSSCQEPTDTPRPAGEPDWVTEFVQKKEERDLVERLREEQVRRRKREE-RLKEVCQDGRLRFAAKRTKHEEEETEALLRLSREMLDAGTGPEQLEQLECGEEHLVLAEYESDEER-RGSR--------VDEAEDDLEEEHITKIYYCSRTHSQLAQFVREVLKSPFG---------KETRLVSLGSRQTLCVNEDVKNLGSVQLMNDRCVDMQRSKR-EKNGTGEDKPKRKRQKIQTSCPFYNHEQMELLRDEILLEVKDMEQLVALGKEARACPYYGSRFAIPAAQLVVLPYPMLLHAATRQAAGIRLQGQVVIIDEAHNLIDTITNIHSTEVNGSQLCQAHSQLLQYMERYRKRLKAKNLMYIKQILYLLEKFVAVLGGNVKQNPTTQSLSQTGSELKSINDFLFQSQVDNINLFKVQRYLEKSMLSRKLFGFTECF---------------GVVLPSLSDSQENRGLAGFQQFLKSLQSGPTE---DSPEEGQAVALR-----PASPLMHIEAFLAALTTANQDGRVIVNRQGSVGQSSLKFLLLNPAVHFAQVVKECRAVVIAGGTMQP------------MSDFREQLLACSGVEAGRVVEFSCGHVIPPDNILPLIICSGPSNQQLEFTYQRRELPQMVE-ETGRILCNLCNVVP--GGVVCFLPSYEYLRQVHAHWDKTGLLTRLSVRKKIFQEPKRASQVEQVLMAYSKCIMSCSHSEGHLTGALLLSVVGGKMSEGINFSDDLGRCVVMVGMPYPNIKSPELQEKMAYLNQTLPRTQG---------QPLPGTVLIENLCMKAIN-----QSIGRAIRHQRDFASIVLLDHR--------YARPSILAKLP--------------AWIRDR---VEVKATFGPAFAAVRK-------------------------FHREKSHPSLV-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MPP1-1", "uniprot_id": "D11L8_HUMAN", "id": "A8MPP1-1", "name": "Putative ATP-dependent DNA helicase DDX11-like protein 8", "aln": "------MANETQKVGAIHFPFP-FTPYS------------IQEDFMAELYRVLEAGK-IGIFESPTGTGKSLSLICGALSWLRDFEQKKREEEARLLETGTGPLHDEKDESLCLSSSCEGAAGTPRPAGEPAWVTQFVQKKEERDLVDRLKVEQARRKQREE-RLQQLQHRVQLKYAAKRLRQEEEETENLLRLSREMLETGPEAERLEQLESGEEELVLAEYESDEEKKVASGHR------VDEDEDDLEEEHITKIYHCSRTHSQLAQFVHEVKKSPFG---------KDVRLVSLGSRQNLCVNEDVRSLGSVQLINDRCVDMQRSRHEKKKGAEEEKPKRRRQEKQAACPFYNHEQMGLLRDEALAEVKDMEQLLALGKEARACPYYRSRLAIPAAKLVVLPYQMLLHAATRQAAGIRLQDQVVIIDEAHNLIDTITGMHSVEVSGSQLCQAHSQLLQYMERYGKRLKAKNLMYLKQILYLLEKFVAVLGGNIKQNPNTQSLSQTGTELKTINDFLFQSQIDNINLFKVQRYCEKSMISRKLFGFTERY---------------GAVFS----SREQPKLAGFQQFLQSLQPRTTEALAAPADESQASVPQ-----PASPLMHIEGFLAALTTANQDGRVILSRQGSLSESTLKFLLLNPAVHFAQVVKECRAVVIAGGTMQP------------VSDFRQQLLACAGVEAERVVEFSCGHVIPPDN-IPLVICSGISNQPLEFTFQKRDLPQMMD-EVGRILCNLCGVVS--GGVVCFFSSYEYLRQVHAHWEKGGLLGRLAARKKIFQEPKSAHQVEQVLLAYSRCIQACGQERGQVTEALLLSVVGGKMSEGINFSDNLGRCVVMVGMPFPNIRSAELQEKMAYLDQTLPRAPG---------QAPPGKALVENLCMKAVN-----QSIGRAIRHQKDFASIVLLDQR--------YARPPVLAKLP--------------AWIRAS---VEVKATFGPAIAAVQK-------------------------FHREKSASS-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q92771-1", "uniprot_id": "DDX12_HUMAN", "id": "Q92771-1", "name": "Putative ATP-dependent DNA helicase DDX12", "aln": "MRSGGGCSGSLSLRGPASFKFSGVCPDSRGLAFSVAILPAKKEDFMAELYRVLEAGK-IGIFESPTGTGKSLSLICGALSWLRDFEQKKREEEARLLETGTGPLHDEKDESLCLSSSCEGAAGTPRPAGEPAWVTQFVQKKEERDLVNRLKAEQARRKQREE-RLQQLQHRVQLKYAAKRLRQEEEERENLLRLSREMLETGPEAERPEQLESGEEELVLAEYESDEEKKVASG--------VDEDEDDLEEEHITKIYHCSRTHSQLAQFVHEVKKSPFG---------KDVRLVSLGSRQNLCVNEDVRSLGSVQLINNRCVDMQRSRHEKKKGAEEEKPKRRRQEKQAACPFYNHEQMGLLRDEALAEVKDMEQLLALGKEARACPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRLQDQVVIIDEAHNLIDTTTSMHSVEVSGSQLCQAHSQLLQYMERYGKRLKAKNLMYLKQILYLLEKFVAVLGGNIKQNPNTQSLSQTGMELKTINDFLFQSQIDNINLFKVQRYCEKSMISRKLFGFTERY---------------GAVFS----SREQPKLAGFQQFLQSLQPRTTEALAAPADESQASVPQ-----PASPLMHIEGFLAALTTANQDGRVILSRQGSLSQSTLKFLLLNPAVHFAQVVKECRAVVIAGGTMQP------------VSNFRQQLLACAGVEAERVVEFSCGHVIPPDNILPLVICSGVSNQPLEFTFQKRDLPQMMD-EVGRILCNLCGVVS--GGVVCFFPSYEYLRQVHAHWEKGGLLGRLAARKKIFQEPKSAHQVEQVLLAYSRCLQACGQERGPVTGALLLSVVGGKMSEGINFSDNLGRCVVMVGMPFPNIRSAELQEKMAYLDQTLPRAPG---------QAHPGKALVENLCMKAVN-----QSIGRAIRHQKDFASIVLLDQR--------YARPPVLAKLP--------------AWIRAR---VEVKATFGPAIAAVQKVSPTFFFLRASQPRDHISHCLLSAQFHREKSASS-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96FC9-1", "uniprot_id": "DDX11_HUMAN", "id": "Q96FC9-1", "name": "ATP-dependent DNA helicase DDX11", "aln": "------MANETQKVGAIHFPFP-FTPYS------------IQEDFMAELYRVLEAGK-IGIFESPTGTGKSLSLICGALSWLRDFEQKKREEEARLLETGTGPLHDEKDESLCLSSSCEGAAGTPRPAGEPAWVTQFVQKKEERDLVDRLKAEQARRKQREE-RLQQLQHRVQLKYAAKRLRQEEEERENLLRLSREMLETGPEAERLEQLESGEEELVLAEYESDEEKKVASR--------VDEDEDDLEEEHITKIYYCSRTHSQLAQFVHEVKKSPFG---------KDVRLVSLGSRQNLCVNEDVKSLGSVQLINDRCVDMQRSRHEKKKGAEEEKPKRRRQEKQAACPFYNHEQMGLLRDEALAEVKDMEQLLALGKEARACPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRLQDQVVIIDEAHNLIDTITGMHSVEVSGSQLCQAHSQLLQYVERYGKRLKAKNLMYLKQILYLLEKFVAVLGGNIKQNPNTQSLSQTGTELKTINDFLFQSQIDNINLFKVQRYCEKSMISRKLFGFTERY---------------GAVFS----SREQPKLAGFQQFLQSLQPRTTEALAAPADESQASTLR-----PASPLMHIQGFLAALTTANQDGRVILSRQGSLSQSTLKFLLLNPAVHFAQVVKECRAVVIAGGTMQP------------VSDFRQQLLACAGVEAERVVEFSCGHVIPPDNILPLVICSGISNQPLEFTFQKRELPQMMD-EVGRILCNLCGVVP--GGVVCFFPSYEYLRQVHAHWEKGGLLGRLAARKKIFQEPKSAHQVEQVLLAYSRCIQACGQERGQVTGALLLSVVGGKMSEGINFSDNLGRCVVMVGMPFPNIRSAELQEKMAYLDQTLSPRPGTPREGSGGEPVHEGRQPVHRQGHQAPEGFCQRSAPGPAICPAPCPGQAAGLDPSPCGGQSYLWPRHCCCAEVSPGEVGLFLMGNHTTAWRRALPLSCPLETVFVVGVVCGDPVTKVKPRRRVWSPECCQDPGTGVSSRRRKWGNPE-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R345-1", "uniprot_id": "DDX11_DANRE", "id": "F1R345-1", "name": "ATP-dependent DNA helicase DDX11", "aln": "------MESKSG-----RFPFP-FQPYP------------IQESFMEALYTALDQRK-VGIFESPTGTGKSLSLICGALTWLRDYEEQRKQEAARLLE-------GQKD-----SDVVKEKNSNSGPP-EPDWVSEFVQKKAERDMVNKLKDEELKRKKREE-RLEMIRHNAQLRYAMKRKADEDDEAVKLLQLSREGAEPETHSPE-------EEGLIVAEYESDDEATPKSRLCDD----DNDDDDDLEEEHVTKIYYCSRTHSQLAQFVHEVQKSPYG---------DAVRLVNLGSRQNLCINPEVVRLGNVQMMNERCLEMQKNKHEKRQKASDSESKRSRGLAKATCVFSRFENLMAMKDEVLVKVRDVEQLIQHGRETHTCPYYSTRMSIPAAQVVVLPYQSLLHASTRKASGIKLKDQIVIIDEAHNLMDTISAIHSAEISGGQLCRAHSQLSQYCERYRSRLKAKNLMYIKQILFVLEGLVRTLGGKVGQNPNTQS-CQTGSELLTINDFLFKAQVDNINLFKVQKYFEKSMISRKLCGFAEKYE------------GSGINTHSSSKNKENRRTEGLGRFLQTLQSKPTD--VSEQQMAVEDKPI-----MASPMMLAESFLFALTNANKDGRVVIQRQACVAQSSLKFLLLNAAVHFAQILQECRAVIIAGGTMQP------------VADFKEQLLFSAGVTEERILEFSCGHVIPPENILPIVLCAGPSGQQLEFTFQTRDSPQMME-ETGRVLSNLCNIVP--GGVVCFFPSYEYEKRILGHWESTGILQRLQSKKKIFQEPKKASQVEQVLSEYSKCIQRCSNIGGGQTGALLFSVVGGKMSEGINFSDDLGRCIVMVGMPYPNIKSPELQEKMAYLDKHMPHVAG----------KSPGKALVESLCMKAVN-----QSIGRAIRHRGDYACIVLCDHR--------YARTGTLQKLP--------------EWIRSS---THTHATFGPAFASARR------------------------FFLEKRQKATL------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XZS9-1", "uniprot_id": "Q9XZS9_DROME", "id": "Q9XZS9-1", "name": "DNA 5'-3' helicase", "aln": "-MSQYTPNQRLDTPGAQEFGFP-YSPYE------------IQEQLMQELFQVLERGQ-VGIFESPTGTGKSLTLTCGALTWLARHEELVRTEMLARIR----------------GVEQELAKLKEESEQSSNWLESQGKSRAQRAELLRLQHLQALLDKQEQ-QLDQIRKG-----AKKHKRQGRVHPGKLEELEKD---------------------LDPESDSDSEHETADG----------PQEAAEDRYRPVQIFFCSRTHSQLAQIVAELRKTPHG---------QSVRSISLGSRQQLCGNPAVRKLKHVGLMNERCLDMA----TKKARPNPSKKSRLTAEANSRCPFKAASLVESLRDLALTEPLDIEELANEGTACGGCSYYASRSAVEHAQLILLPYQLLLQKSARNQLGISLKGSIVIVDEAHNLLDSVAQLHGSEISRQQLERAKVQISGYKDHFQKRFTTKNLLKINQIIFIIRRLLKILD-------QRKELQSNGCSMMRTYELTAEGDFFNIDLCELLDFCARTRFARKVQGRADRMEREPRPSENQAPVSTARSLILQRLASEQKLKEKTKSVKRRVEDINKEDKAEELQEQQKPTKKPVEEVAPSPIRPLLAFLETLTSNAEDGRILVDPVG----GTLKYILLDPAEQFADIVAEARAIVIAGGTMQP------------TKELKEQLFTGC---HDRLVERFYNHVVANDAILPFVISNGPSGAPLSFKFAHRGSAEMLR-ELSMILRNLCQVVP--GGVVCFLPSYEYLDKVYKYLEQSGTLETISGRKSVFREVS--GSAEQLLDNYALAIKRPAS-----YGALLLSVVGGKLSEGLNFADDLGRAVLVVGLPYSNSLSPELRQRMQHLDEKLGPGAG--------------NEYYENLCVKAVN-----QCIGRAVRHIKDYACVYLLDKR--------FADPKIRGKLP--------------KWISRH--IVEANAANG-GFGAVQG-------------------------RTARFFKGR-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22516-1", "uniprot_id": "CHL1_YEAST", "id": "P22516-1", "name": "ATP-dependent DNA helicase CHL1", "aln": "---------MDKKEYSETFYHP-YKPYD------------IQVQLMETVYRVLSEGKKIAILESPTGTGKTLSLICATMTWLRMNKADIFTRMETNIKTNEDDSENLSD---DEPDWVIDTYRKSVLQEKVDLLNDYEKHLNEINTTSCKQLKTMCDLDKEHGRYKSVDPLRKKRKGARHLDVSLEEQDFIPRPYESDSENNDTSKSTRGGRISDKDYKLSELNSQIITLLDKIDGKVSRDPNNGDRFDVTNQNPVKIYYASRTYSQLGQFTSQLRLPSFPSSFRDKVPDEKVKYLPLASKKQLCINPKVMKWKTLEAINDACADLR-------------HSKEGCIFYQNTNEWRHCPDTLALRDMIFSEIQDIEDLVPLGKSLGICPYYASREALPIAEVVTLPYQYLLSESTRSSLQINLENSIVIIDEAHNLIETINSIYSSQISLEDLKNCHKGIVTYFNKFKSRLNPGNRVNLLKLNSLLMTLIQFIVKN----------FKKIGQEIDPNDMFTGSNIDTLNIHKLLRYIKVSKIAYKID-----------------------------------------TYNQALKEEESSKNENPIKETHKKSVS-----SQPLLFKVSQFLYCLTNLTSEGQFFFEKNYS-----IKYMLLEPSKPFESILNQAKCVVLAGGTMEP------------MSEFLSNLLPEVP--SEDITTLSCNHVIPKENLQTYITNQ----PELEFTFEKRMSPSLVNNHLFQFFVDLSKAVPKKGGIVAFFPSYQYLAHVIQCWKQNDRFATLNNVRKIFYEAK---DGDDILSGYSDSVAEGRG-------SLLLAIVGGKLSEGINFQDDLCRAVVMVGLPFPNIFSGELIVKRKHLAAKIMKSGG-----TEEEASRATKEFMENICMKAVN-----QSVGRAIRHANDYANIYLLDVR--------YNRPNFRKKLS--------------RWVQDS---INSEHTTHQVISSTRK------------------------FFSMRSLNSR-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .. * : .:* :: .*. : :.*:********:*:* *.:::** : : . . : . : : : .:*. : . : . :: . : . .. .* :*: . . . .:*:..***:***.*:. :: ... . .: : *.*:: ** * * : :*: * :: . .. : : ::* : : *:*:* * *.** :* :: *::: *** ** ::*. * *:..:**:******::: ::. ::. :* ..: : * ::: .*:.. * : : :: :: :: : .. . :: .:. .::: :: : : :: *: : :: . . . : ** **. .:*:.... :*::**:.: * .:: :.:.:::*****:* :: .:*: : .**:. : . : *.*.: * ..:: . .: :*. *. **:*.*:.**:* :: .. . : : :.:* * . . :::* *: .: :**:::****:***:** *:* *.:::**:*:.* * ** : :* : * . :* : .. * *: . * : ::. * . . . . . ", "identical_positions": 130, "similar_positions": 262, "identity": "12.33%" }, { "cls_id": "homologset.agr.SGD:S000005930", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ARH7-1", "uniprot_id": "A0A8I6ARH7_RAT", "id": "A0A8I6ARH7-1", "name": "Ribosome quality control complex subunit NEMF", "aln": "MTESFASTKSMIYYMFRFCSLLGMRVNNVYDVDNKTYLIRLQ--KPDFKATLLLESGIRIHTTEFEWPKNMMPSSFAMKCRKHLKSRRLVSAKQLGVDRIVDFQFGSDEAAYHLIIELYDRGNIVLTDYEYLILNILRFRTDEADDVKFAVRERYP-IDHARAAEPLLTLERLTEVIARAPRGELLKRVLNPLLPYGPALIEHCLIEN---GFS--------------------------GNVKVDEKLESK------DIEKILVCVQRAEDYLEKT--------ANFNGKGYIIQKREVKPSLDANKPAEDILTYEEFHPFLFSQH-----LQCPYIEFESFDKAVDEFYSKIEGQKIDLKALQQEKQALKKLDNVRKDHENRLEALQQAQEIDKLKGELIEMNLQIVDRAIQVVRSALANQIDWTEIGVIVKEAQAQGDPVASAIKE-LKLQTNHITMLLRNP---YLLSEEEDG--DGDGSIENSDAEAPKGKKKKQKNKQLQKPQKNKPLLVDVDLSLSAYANAKKYYDHKRYAAKKTQRTVEAAEKAFKSAEKKTKQTLKEVQTVTS--IQKARKVYWFEKFLWFISSENYLIIGGRDQQQNEIIVKRYLTPGDIYVHADLHGATSCVIKNPTGDPIPPRTLTEAGTMALCYSAAWDARVITSAWWVHHHQVSKTAPTG-EYLTTGSFMIRGK--KNFLPPSYLMMGFSFLFKVDESCVWRHRGERKVRVQDEDMETLTSCTSELMSEEMEQLEGGDSSEEETEELRGTTEEVELRTQADPEDIAAHSGREEL--------SSEDGEAIKTATKDEEPIGEVREEEEEPFEYPDTTIDLSHLQSQRPLQKLTPREESFNSSDSKSQSRRHLSAKERREMKKKKLPCDSGDLEVIEEKDKEKESAVHSEADQNTSKNVAAGQPMKRGQKSKMKKMKEKYKDQDDEDRELIMKLLASAGSNKEEKGKKGKKGKTKDEPVKKNPQKPRGGQRVLD-VVKETPSLQASTPDLQDFAVDEPHDDKEEHDLDQQGNEENLFDSLTGQPHPEDVLMFAIPICAPYTIMTNYKYKVKLTPGVQKKGKAAKTALNSFMH---------SKEATAREKDLFRSVKDTDLSRNIPG-KVKVSAPNLLHVKRK-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CCP0-1", "uniprot_id": "NEMF_MOUSE", "id": "Q8CCP0-1", "name": "Ribosome quality control complex subunit NEMF", "aln": "MKSRFSTVDLRAVLAELNASLLGMRVNNVYDVDNKTYLIRLQ--KPDFKATLLLESGIRIHTTEFEWPKNMMPSSFAMKCRKHLKSRRLVSAKQLGVDRIVDFQFGSDEAAYHLIIELYDRGNIVLTDYEYLILNILRFRTDEADDVKFAVRERYP-IDHARAAEPLLTLERLTEVIAAAPKGEVLKRVLNPLLPYGPALIEHCLIES---GFS--------------------------GNAKVDEKLESK------DIEKILVCVQRAEDYLRKT--------SNFNGKGYIIQKREAKPSLDADKPAEDILTYEEFHPFLFSQH-----LQCPYIEFESFDKAVDEFYSKIEGQKIDLKALQQEKQALKKLDNVRKDHENRLEALQQAQEIDKLKGELIEMNLQIVDRAIQVVRSALANQIDWTEIGVIVKEAQAQGDPVACAIKE-LKLQTNHVTMLLRNP---YLLSEEEDG--DGDASIENSDAEAPKGKKKKQKNKQLQKPQKNKPLLVDVDLSLSAYANAKKYYDHKRYAAKKTQRTVEAAEKAFKSAEKKTKQTLKEVQTVTS--IQKARKVYWFEKFLWFISSENYLIIGGRDQQQNEIIVKRYLTPGDIYVHADLHGATSCVIKNPTGEPIPPRTLTEAGTMALCYSAAWDARVITSAWWVYHHQVSKTAPTG-EYLTTGSFMIRGK--KNFLPPSYLMMGFSFLFKVDESCVWRHRGERKVRVQDEDMETLTSCTSELMAEEMEQLEGGDSSEEETEELHGMPGDVELMTQVDQEDIAVHSGRDEL--------SSEDGE-AKAVTKDQEPIGEMKEEEEDTFEYPDTTIDLSHLQSQRPLQKLAPREESLNSNDSKSQGRRHLSAKERREMKKKKLPCESGDLEVIEEKDKERESAVHTEAYQNTSKNVAAGQPMKRGQKSKMKKMKEKYKDQDDEDRELIMKLLASAGSNKEEKGKKGKKGKPKDEPVKKPPQKPRGGQRVLD-VVKEPPSLQVLAHDLQDLAVDDPHDDKEEHDLDQQGNEENLFDSLTGQPHPEDVLMFAIPICAPYTIMTNYKYKVKLTPGVQKKGKAAKTALNSFMH---------SKEATAREKDLFRSVKDTDLSRNIPG-KVKVSAPNLLHVKRK-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60524-1", "uniprot_id": "NEMF_HUMAN", "id": "O60524-1", "name": "Ribosome quality control complex subunit NEMF", "aln": "MKSRFSTIDLRAVLAELNASLLGMRVNNVYDVDNKTYLIRLQ--KPDFKATLLLESGIRIHTTEFEWPKNMMPSSFAMKCRKHLKSRRLVSAKQLGVDRIVDFQFGSDEAAYHLIIELYDRGNIVLTDYEYVILNILRFRTDEADDVKFAVRERYP-LDHARAAEPLLTLERLTEIVASAPKGELLKRVLNPLLPYGPALIEHCLLEN---GFS--------------------------GNVKVDEKLETK------DIEKVLVSLQKAEDYMKTT--------SNFSGKGYIIQKREIKPSLEADKPVEDILTYEEFHPFLFSQH-----SQCPYIEFESFDKAVDEFYSKIEGQKIDLKALQQEKQALKKLDNVRKDHENRLEALQQAQEIDKLKGELIEMNLQIVDRAIQVVRSALANQIDWTEIGLIVKEAQAQGDPVASAIKE-LKLQTNHVTMLLRNP---YLLSEEEDDDVDGDVNVEKNETEPPKGKKKKQKNKQLQKPQKNKPLLVDVDLSLSAYANAKKYYDHKRYAAKKTQKTVEAAEKAFKSAEKKTKQTLKEVQTVTS--IQKARKVYWFEKFLWFISSENYLIIGGRDQQQNEIIVKRYLTPGDIYVHADLHGATSCVIKNPTGEPIPPRTLTEAGTMALCYSAAWDARVITSAWWVYHHQVSKTAPTG-EYLTTGSFMIRGK--KNFLPPSYLMMGFSFLFKVDESCVWRHQGERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHELQDFAVDDPHDDKEEQDLDQQGNEENLFDSLTGQPHPEDVLLFAIPICAPYTTMTNYKYKVKLTPGVQKKGKAAKTALNSFMH---------SKEATAREKDLFRSVKDTDLSRNIPG-KVKVSAPNLLNVKRK-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VBX1-1", "uniprot_id": "NEMF_DROME", "id": "Q9VBX1-1", "name": "Ribosome quality control complex subunit NEMF homolog", "aln": "MKTRFNTFDIICGVAELQK-LVGWRVNQIYDVDNKTYLFRMQGTGAVEKVTLLIESGTRFHTTRFEWPKNMAPSGFSMKLRKHLKNKRLEKVQQMGSDRIVDFQFGTGDAAYHVILELYDRGNVILTDYELTTLYILRPHT-EGENLRFAMREKYP-VERAKQPTKELELEALVKLLENARNGDYLRQILTPNLDCGPAVIEHVLLSH---GLDNHVIKKETTEETPEAEDKPEKGGKKQRKKQQNTKLEQKPFDMVNDLPILQQAVKDAQELIAEG--------NSGKSKGYIIQVKEEKP--TENGTVEFFFRNIEFHPYLFIQF-----KNFEKATFESFMEAVDEFYSTQESQKIDMKTLQQEREALKKLSNVKNDHAKRLEELTKVQDVDRKKAELITSNQSLVDNAIRAVQSAIASQLSWPDIHELVKEAQANGDAVASSIKQ-LKLETNHISLMLSDP---YDNDEDDD----------------------------LKDPEVT---VVDVDLALSAWANARRYYDMKRSAAQKEKKTVDASQKALKSAERKTQQTLKEVRTISN--IVKARKVFWFEKFYWFISSENYLVIGGRDAQQNELIVKRYMRPKDIYVHAEIQGASSVIIQNPTGEEIPPKTLLEAGSMAISYSVAWDAKVVTNSYWVTSDQVSKTAPTG-EYLATGSFMIRGK--KNFLPSCHLTMGLSLLFKLEDSFIERHLGERKVRSLEDDQIDPNVKENEVEHDLLSDNEDADSNINLSEPSSNTEITAFPNTEVK---IEHDTG--------------------RIIVRSDSVNPEIEETKE------------SEVVLDKILKKTDDEETTIILAGPSR--KKQVSAKKTK-----------------EDKARAKQEAAKQEVPPVSSEPKNPSQ-VKRGQKGKLKKMKQKYKDQDDEEREIRMMILKSSG--KEKPQASADKVVEKSESTKEYVKPEKS-------------------------AAPKNPVELDDADEVPVGGDVDVLNSLTGQPHEGDELLFAIPVVAPYQALQNYKFKVKLTPGTGKRGKAAKLALNIFAK---------EKSCSAREKDLLKSIKEESLARNIPG-KVKLSAPQLQKYHK------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12532-1", "uniprot_id": "RQC2_YEAST", "id": "Q12532-1", "name": "Ribosome quality control complex subunit 2", "aln": "MKQRISALDLLLLARELKQDLEGYRLSNIYNIADSSKQFLLKFNKPDSKLNVVVDCGLRIYLTEFSRPIPPTPSGFVVKLRKHLKAKRLTALKQVDQDRILVLQFADG--HFYLVLEFFSAGNVILLDENRRIMALQRVVLEHENKVGQIYEMFDESLFTTNNESADESIEKNRKAEYTSELVNEWIKAVQAKYESDITVIKQLNIQGKEG-------AKKKKVKVPSIHKLLLSKVPHLSSDLLSKNLKVFNIDPSESCLNLLEETDSLAELLNSTQLEYNQLLTTTDRKGYILAKR-NENYISEKDTADLEFIYDTFHPFKPYINGGDTDSSCIIEVEGPYNRTLDKFFSTIESSKYALRIQNQESQAQKKIDDARAENDRKIQALLDVQELNERKGHLIIENAPLIEEVKLAVQGLIDQQMDWNTIEKLIKSEQKKGNRIAQLLNLPLNLKQNKISVKLDLSSKELNTSSDEDNESEGNTTDSSSDSDSEDMESSKERSTKSMKRKSNEKINVTIDLGLSAYANATEYFNIKKTSAQKQKKVEKNVGKAMKNIEVKIDQQLKKKLKDSHSVLKKIRTPYFFEKYSWFISSEGFLVMMGKSPAETDQIYSKYIEDDDIYMSNSFN--SHVWIKNPEKTEVPPNTLMQAGILCMSSSEAWSKKISSSPWWCFAKNVSKFDGSDNSILPEGAFRLKNENDQNHLPPAQLVMGFGFLWKVKTSGNEDNGDDDEEEEEEEEEEEEEEEEEEEEEEEEKEEEEKEEEQQQDEDDSNEVNGLEKGGDSN------------------------------DSTKNNS---------------------FEHDNLEKDIEKHCTISSDTDSDSGNAKAKNDNSS----------------------TQRILDEPGVPISLIENINSN-------VRGKRGKLKKIQKKYADQDETERLLRLEALGTLKGIEKQQQRKKEEIMKREVREDRKNKREKQRR-----------------------LQALKFTKKEKARVNYDKHKSELKPSLD----KGDVVDDIIPVFAPWPALLKYKYKVKIQPGSAKKTKTLTEILHYFKSRPLDGSSTDNEMDWPQEHEMIKGLKEQDLVLLLCVDKLKVTIAGQKSTKNGGNSSKKGKKKR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : : . * * *:.::*:: :.: : :: . * .::::.* *:: *.*. * **.* :* ***** :** :*:. ***: :**. . :::::*::. **::* * : : : * . :.: . : :. :* : : : : : . . ::*:: :. . . :*: . : . : : . . ****: : : . ..: : ***: . .: .::*:*:*. *..* :: :** :* **:.:.: :: .::: * ..*:::. *..** * :::.. .*:. : .*:.* * ::*. * :*: :* :: *:*: *:::: * . ..::* . : . * :**.***:*** .*:: *: :*:* ::. . **:*. * * .* **: . : : * *. ::***: ******.:*:: *:. :.: * .:*: ***: .:: : *:** :**.** :** :.:. * **. :: :..:* .:*** :. . *. *:* ::.: :*.**.. * **:.:*:*:. * : .: : . ::: .* : .: : : . : : : . :.:. .. :: ::* . . . :.. *: : : . . .. **::.*:**:::** ***: :* : : * : ::: . .: :. .. : : . :. . :: ** * : **: **: : :**:***: ** *: *: . *: * .: .:*:::::.:*: .* : *:*:: . :. ", "identical_positions": 178, "similar_positions": 340, "identity": "15.38%" }, { "cls_id": "homologset.agr.SGD:S000005931", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LAY8-1", "uniprot_id": "A0ABK0LAY8_RAT", "id": "A0ABK0LAY8-1", "name": "Coatomer subunit zeta", "aln": "MRFCGVGGLAESSFRERGRTQRPATQDWVEGQRRGGRARGGAALSVQAASGMQRPEAWPRPHPGEGASAAQAGGAAPPTRA---TEQRFQEPSLYTIKAVFILDNDGRRLLAKYYDDTFPS----------MKEQMVFEKNVFNKTSRTESEIAFLAGMTIVYKSSIDIFLYVVGSSSENELMLMSVLACLFDSLSHILRKNVEKRWLLENMDGAFLVLDEIVDGGVILESDPQQVIQKVNFRTDDSGLTEQSVAQVLQSAKEQIKWSLLK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHH9-1", "uniprot_id": "COPZ2_MOUSE", "id": "Q9JHH9-1", "name": "Coatomer subunit zeta-2", "aln": "---------------------------------------------------MQRPEAWPRPHPGEGASAAQAGGAAPPTRA---TEQR--EPSLYTIKAVFILDNDGRRLLAKYYDDTFPS----------VKEQMVFEKNVFNKTSRTESEIAFLGGMTIVYKSSIDIFLYVVGSSSENELMLMSVLACLFDSLSHILRKNVEKRWLLENMDGAFLVLDETVDGGVILESDPQQVIQKVNFRTDDSGLTEQSVAQVLQSAKEQIKWSLLK------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P299-1", "uniprot_id": "COPZ2_HUMAN", "id": "Q9P299-1", "name": "Coatomer subunit zeta-2", "aln": "---------------------------------------------------MQRPEAWPRPHPGEGAAAAQAGGPAPPARAGEPSGLRLQEPSLYTIKAVFILDNDGRRLLAKYYDDTFPS----------MKEQMVFEKNVFNKTSRTESEIAFFGGMTIVYKNSIDLFLYVVGSSYENELMLMSVLTCLFESLNHMLRKNVEKRWLLENMDGAFLVLDEIVDGGVILESDPQQVIQKVNFRADDGGLTEQSVAQVLQSAKEQIKWSLLK------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61923-1", "uniprot_id": "COPZ1_HUMAN", "id": "P61923-1", "name": "Coatomer subunit zeta-1", "aln": "------------------------------------------------------------------------------------MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPS----------VKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLLR------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GES6-1", "uniprot_id": "A0A8I6GES6_RAT", "id": "A0A8I6GES6-1", "name": "Coatomer subunit zeta", "aln": "------------------------------------------------------------------------------------MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPS----------VKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLLR------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61924-1", "uniprot_id": "COPZ1_MOUSE", "id": "P61924-1", "name": "Coatomer subunit zeta-1", "aln": "------------------------------------------------------------------------------------MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPS----------VKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLLR------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VV89-1", "uniprot_id": "Q9VV89_DROME", "id": "Q9VV89-1", "name": "Coatomer subunit zeta", "aln": "----------------------------------------------------------------------------------------MDGFMMDIIKGMCIMDNDGNRILAKYYDKNILST---------LKEQKAFEKNLFNKTHRSNTEIIMLDGLTCVYKSNVDLFFYVMGNAYENELILLSVLNCLYDSISLILKKNVEKRLVLENLEIIMLAFDEICDGGIILDADPSSVVKRVDLRNDDIPIAEQTVAQVLQSAREQLKWSILK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53600-1", "uniprot_id": "COPZ_YEAST", "id": "P53600-1", "name": "Coatomer subunit zeta", "aln": "----------------------------------------------------------------------------------------MSSLSLYTVQAVLILDQQGERIYAKYYQPPHRSDEGHQLLFNSVKKQKEFEKQLYRKTHKQDSEILIFEDHLVLYKEYIDITIYLVASLEENEIVLQQGFSAIRGALDLILNSGMDKKNIQENYDMVLLAIDETIDNGVILETDSNTIASRVSKPPTNEPQMALDLDKGFLGAWGFAKSKFQERLQQGL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::.: *:*::* *: ****: * :*:* ***:::.** : ::** :: . :**. :*: :*::.. ***::* : .: ::. :*...::*: : ** : :*..** *.*:**::*.. : :* : : : : .* * .: . ", "identical_positions": 41, "similar_positions": 67, "identity": "14.8%" }, { "cls_id": "homologset.agr.SGD:S000005933", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R3M8-1", "uniprot_id": "M0R3M8_RAT", "id": "M0R3M8-1", "name": "", "aln": "MGRSGKLPSGVSAKLKRWKKGHSSDSNPTTCRHRQAARSRFFSR-----PSGKSDLTVDAVKLHNELQ------------SGTLSLGKSQAPETTMD------QDPEVAFTEKSSGTFLSGLSDCTNVTFSKVQRFWESNSAAHKEICAVLAAVTEVIRSQGGKETETEYFAALMTTMEAVESPESLAAVAYLLNLVLKRVPSPVLMKKFSDTSKAFMNIMSAQASSGSTSALRWVLSCLAILLRKQDLEAWGYPITLQVY-----HGLLSFTVHAKPKVRKAAQHGVCSVLKG-----SDFMFGEEAPA--------------HHPAAVSTAKFCIQEIE----------------KSGGSREATTTLHMLTLLKDMLPC--FPEGLVKSCSETLLRVMTLNHVLVTACAMQAFHNLFHAKPSPSTLS---AELNAQIITALYDYVPSENDLQPLLAWLKVMEKAHINLVRLQRDLGLGHLARFFGIAVT-CLLSPHSQVVAAATQTLKEILRECVAPHVADIG-SVTS-SASGPPQYIAKMFRAVEEGLTYRFHAAWSSVLQLLGVFFEACGKQAHPVMKKCLQSLCDLRLSPHFPHTA--ALDQAVGAAVTSMGPEVVLQAVPLEIDGSEETLDFPRSWLLPVIRDHVRETRLGFFTTYFLPLATALKRKAMDLAQAGSAVESKIYDTLQWQIWTLLPGFCIRPTDVAASFKGLAR-TLGTAISERPDLRVTVCQALRTLITKGC--------------------EAEADRAEVSRFAKNFLPILFNLYGQPVAAGEAEAPRRAVLETIKTYLTITESQ------------LVNGFLEKATEKVLDPASSDFTRLSVLDLVVALAPYSDEAAISKLYSTIRPYLESKVHG------------VQKKAYRVLEEVCASSQGPAARFVQSHLDDLKKTLLDSLQSTSSPAKRPRLKCLIHIVKKLS--AEHEEFIAALIPEVILCTKEVSVGARKNAFTLLVEMG---------------HAFLRFDSSQEEALQRYLVLIYPGLLG-AVTTVSCSILALTHLLFEFKGLMGTSTVEQLLENVCLLLASRTRDVVKSALGFIKVAVVVMDVVHLAKHVQLVLEAIGKLSDDMRRHFRMKLRNLFIKFIRKFGSVFELVKDLLPAEYHKVLVNIRKAETRAKKHRALSQAAMEEEEE-EEEEK-PVQSKGDSIEEILADS-----EDED--EEEERSQGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAHRVLAT---------QPGPGRGKKKDHGFKLSADGRLIIREEEDGDKVEEEDVTKGEDEEMTDVMEDASVRSKK--KLKRQRE-DEEDELEIPPR---------------------YQAGGSGIHRPVAKKAA--------------PGAEYKAKKAKGDVKRKGRLDPYAYVPLNRTKLNRRKKVKLQGQFKGLVK--AAQRGSQVGHKLHRKDRRP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P5B0-1", "uniprot_id": "RRP12_MOUSE", "id": "Q6P5B0-1", "name": "RRP12-like protein", "aln": "MGRSGKLPSGVSAKLKRWKKGHSSDSNPATCRHRQAARSRFFSR-----PSGKSDLTVDAVKLHNELQ------------SGTLSLGKSQAPETTMD------QDPEVAFTEKSSGTFLSGLSDCTNVTFSKVQRFWESNSAAHKEICAVLAAVTEVIRSQGGKETETEYFAALMTTMEAVESPESLAAVAYLLNLVLKRVPSPVLMKKFSDTSKAFMDIMSAQASSGSTSALRWVLSCLAILLRKQDLEAWGYPITLQVY-----HGLLSFTVHAKPKIRKAAQHGVCSVLKG-----SDFMFGEKAPA--------------HHPAAVSTAKFCIQEIE----------------KSGGSKEATTTLHMLTLLKDMLPC--FPEGLVKSCSETLLRVMTLNHVLVTACAMQAFHNLFHAKPSPSTLS---AELNAQIVTALYDYVPSENDLQPLLAWLKVMEKAHINLVRLQRDLGLGHLARFFGTAVT-CLLSPHSQVAAAATQTLKEILKECVAPHIADIG-SVTS-SASGPPQYITKMFRAVEEGLTYKFHAAWSSVLQLLGVFFEACGKQAHPVMKKCLQSLCDLRLSPHFPHTA--ALDQAVGAAVTSMGPEVVLQAVPLEIDGSEETLDFPRSWLLPVIRDHVRETRLGFFTTYFLPLATTLKRKAMDLAQAGSTVESKIYDTLQWQIWTLLPGFCTRPTDVAASFKGLAR-TLGTAINERPDLRVTVCQALRTLITKGC--------------------EAEADRAEVSRFAKNFLPILFNLYGQPVAAGEAAAPRRAVLETIKTYLTITEAQ------------LVNSFLEKATEKVLDPASSDFTRLSVLDLVVALAPYSDEAAISKLYSTIRPYLESKVHG------------VQKKAYRVLEEVCASSQGPAARFVQSHLDDLKKTLLDSLRTTSSPAKRPRLKCLIHIVKTLS--AEHEEFIAALIPEVILCTKEVSVGARKSAFTLLVEMG---------------HAFLRFGSNQEDALQRYLVLIYPGLLG-AVTTVSCSILALTHLLFEFKGLMGTSTVEQLLENVCLLLASRTRDVVKSALGFIKVAVVVMDVVHLAKHVQLVMEAIGKLSDDMRRHFRMKLRNLFIKFTRKFG--FELVKGLLPAEYHKVLINIRKAETRAKKHRALSQAAVEEEEE-EEEEEEPVQSKGDSIEEILADS-----EDED--EEEERGRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAHRVLAT---------QPGPGRGKKRDHGFKLSADGRLIIREEEDGNKVEEEDGTKGEDEDMTDAMEDASVRSKK--KLKRQRE-DEEDELEIPPR---------------------YQAGGSGIHRPVAKKAA--------------PGAEYKAKKAKGDVKKKGRLDPYAYVPLNRSKLNRRKKVKLQGQFKGLVK--ATQRGSQAGHKLRRKDRRRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JTH9-1", "uniprot_id": "RRP12_HUMAN", "id": "Q5JTH9-1", "name": "RRP12-like protein", "aln": "MGRSGKLPSGVSAKLKRWKKGHSSDSNPAICRHRQAARSRFFSR-----PSGRSDLTVDAVKLHNELQ------------SGSLRLGKSEAPETPME------EEAELVLTEKSSGTFLSGLSDCTNVTFSKVQRFWESNSAAHKEICAVLAAVTEVIRSQGGKETETEYFAALMTTMEAVESPESLAAVAYLLNLVLKRVPSPVLIKKFSDTSKAFMDIMSAQASSGSTSVLRWVLSCLATLLRKQDLEAWGYPVTLQVY-----HGLLSFTVHPKPKIRKAAQHGVCSVLKG-----SEFMF-EKAPA--------------HHPAAISTAKFCIQEIE----------------KSGGSKEATTTLHMLTLLKDLLPC--FPEGLVKSCSETLLRVMTLSHVLVTACAMQAFHSLFHARPGLSTLS---AELNAQIITALYDYVPSENDLQPLLAWLKVMEKAHINLVRLQWDLGLGHLPRFFGTAVT-CLLSPHSQVLTAATQSLKEILKECVAPHMADIG-SVTS-SASGPAQSVAKMFRAVEEGLTYKFHAAWSSVLQLLCVFFEACGRQAHPVMRKCLQSLCDLRLSPHFPHTA--ALDQAVGAAVTSMGPEVVLQAVPLEIDGSEETLDFPRSWLLPVIRDHVQETRLGFFTTYFLPLANTLKSKAMDLAQAGSTVESKIYDTLQWQMWTLLPGFCTRPTDVAISFKGLAR-TLGMAISERPDLRVTVCQALRTLITKGC--------------------QAEADRAEVSRFAKNFLPILFNLYGQPVAAGDTPAPRRAVLETIRTYLTITDTQ------------LVNSLLEKASEKVLDPASSDFTRLSVLDLVVALAPCADEAAISKLYSTIRPYLESKAHG------------VQKKAYRVLEEVCASPQGPGALFVQSHLEDLKKTLLDSLRSTSSPAKRPRLKCLLHIVRKLS--AEHKEFITALIPEVILCTKEVSVGARKNAFALLVEMG---------------HAFLRFGSNQEEALQCYLVLIYPGLVG-AVTMVSCSILALTHLLFEFKGLMGTSTVEQLLENVCLLLASRTRDVVKSALGFIKVAVTVMDVAHLAKHVQLVMEAIGKLSDDMRRHFRMKLRNLFTKFIRKFG--FELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEE-EEEEEEPAQGKGDSIEEILADS-----EDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLAT---------QPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKE-AEEEELEIPPQ---------------------YQAGGSGIHRPVAKKAM--------------PGAEYKAKKAKGDVKKKGRPDPYAYIPLNRSKLNRRKKMKLQGQFKGLVK--AARRGSQVGHKNRRKDRRP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4KMF4-1", "uniprot_id": "RRP12_DANRE", "id": "Q4KMF4-1", "name": "RRP12-like protein", "aln": "MVKSGKLRSGAAQKVRRWKKGHSSDSNPETNRYRKAARSRYFSR-----PSEKSDLTVDALKLHNDLQ------------SGSLQQS-SDVAGDSME------DEA---LTEKTSGTFLSGLSDCSNLTFRKVQRYWESNSATHKEICAVLAAVTEVIRSQGGKETETEYFAALMTTLEAVDSSESLAAVAYLLNLVMKRMPPAVLKKKFSDTAKAFMDAISNQSNSYSILYLRWILSCLATLLRKQDLSVWSYPSTLQVY-----HGLLSFTVHSKPKVRKAAQQGICSVLRY-----SDFMFSDNAPN--------------HHPAAVSTAKFCCKELE----------------QSGGSKEDTTTLHILGLLKDLLSA--FPLSSVKSCCETLLRVMTLSHVLVTAHAMQAFHKLFISKPSTSSMS---AELNAQIITALYDYVPSENDLQPLLAWLAVMEKAHVHLSSLQSSLCLGHLPRLFSVTMS-CLLSPHTQVVSAAASTMKTLINDCVASHMAEIG-PVQPNTSSGNGACVLKMFHIVEEGLSYRFHASWPFVLKILGCFYRAAGKQAHPIMIKSLQSLSDLRATPQFPFTG--ELDLAVGGAVESMGPEVVLNAVPLLITGTDDDLEFPRSWLIPVIRDHVKNSQLAYFNSHFFPLANKLKQTADELEQSGQKLMAKVYQTLQMQIWTMLPGFCTKPTDLLVSFKGIAR-SLGMALNDRPDLRMCICQALRTLINKSC--------------------ETEEEKAEMNRFSKNFLPILFNVYSQQPKPGEMTSARMAVLDTIRVYLTITDQT------------MVCTFLQKALER-LNADNTEFTRLAVIDLVVAMAPFVDEASMSQILEFIKPFVESKDTG------------IQKKAYRVLEEICGGERASCKAFVLANLEQLKKMLMESLKTAASPAKRPRLKCLIHIVKQLN--EEHRDFITALLPEVILCTKEMSIGARKNAYTLLVEIG---------------NAFERFCGNTKDAINEYLGYVYIGLTG-SVTLITCTVLALTRLIFHYKDSIDLSSLELLLQNVCLLLTSRTRDIVKASLGFLKVIIFSLDVKVLAGHVNVIMEGISNMN-DMRRHFRVKLKNIYTKLIRKFG--FELVKSMLPAEQHKVLGNIRKSEARNKKR----KLTKTEEDE-SDTEDGKPKVKGESIEDILAET-----DSDDSDEDEKRKKG--QKKPMKKKGQAWLKEGVSDEPLNFLDPKAAQRVLAT---------NPNLKKATKADHGFKVTSDGRLIIKEEDDDDYEEE----KTKDAEMDDVLEEAGVKTKKNPKRKIAADLDDDMDVEPALK---------------------YKAGGIGIHRPLGGRPE--------------IGTEYKSKKGKGDIKKAGKCDPYAYIPLKKSQLNRRKKAKLQGQFKGMVR--GAKKGALSGSRILKKRKA--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYA7-1", "uniprot_id": "RRP12_DROME", "id": "Q9VYA7-1", "name": "RRP12-like protein", "aln": "-MGKFRSKLKRNGKGKTWSRGESATSNPTQMKHRMKAKSRFFQPNLSLAAATTTGLTMEAVHKHEQSQAFNAETTTVNDVAGSLRSFKLDDDDDGMSGSGTAPTGTAPTGTIKTFQTFASNYSGCSNTCFQKLVTSFRSSSALHKEMLAILSALTEIIRENGGGESSTEYFLLLMEQIEAATEERDIVAGVTLLAMGINSVPAPVLKKRFAQTADTMQRLLQRFMESTNQSVIRHVIGCLSVILRAQDYAAWSYSSTFQYF-----DAILAFSIHSQPKIRKAAQHAIALIIHG-----SCFMLPAIKSDDNEMDEAVEQPKVKHHPASSRVAKFCLAQFK----------------PEVLANAQTTVLHTLELLKDTLYG--FKTEDIRSVCEHLLSIMTAANVLVRTNCFQTLYSLFLKK--SPNLN---ASLCAKLLAAIHEYRPDKSDIRQTIAWVTVLKEGHLHLATMQLDLCMQALPRLIDVCTTDLWLSDQKELVAGVSNCIKELLQDCVSRACATAE-DAQC-----NRQSVSRIIASLHKMLNAPFGEISRFVILIFSFVFEACGKLFGSELTPPLMTICKR-YDTQSAHRL--QIEHTVISAIKALGPELVLTAIPLAD--GKGVMQLERSWLLPLLREGANGASLQFFKEKIVALAMDCQLKWKEFAEAKNNSSSHIYELLCCQLWGLFPGFCRQPRDPEY-LRYLAP-TLGAAVEKNPEFRPPIYDGLMELLGDNQ--------------------SAECHQAIG-QYAKNFLPRLFNIYTQKPNGTYEADQRKRVLEVIRLYISRAPAD------------VQLELFENAQEQLAASALASFEYDAFFDINAAIVRVQTCKGIKAYFDKYMAPILRNDKSKLVAKDEQKLKKQQRKTYELLRELMTSELPSCQKFTRKNSIVLQQILLDSFNTSCNVCQASRLHCLKSLIDCHSNLAYNDQLVMKAIPEAVLNYKEFSNYKEQVAEQLIKSIT---------------QLYHDAG-----KINDFVDILTAGFAG-DEMLVTNTILAFRAVLQQQGEHLTVATLEFVLQQVSVFLVQKSRKQAEAAIAFLITFIKVMPIPLVANHLEAIMRSLSAMTKDTKRYCRIQIGYLLKKLCIRFS--PGELAGFVPGDDDVIHRRLKMIRKRTRRDLRKKQNLEAQEDSSDDELVSGLQEKSYTIDDMLADSDSDLPEDMDAKDEAGAAAAASKRSKNAKQQKSTYIREDPDEIVDLADLKSIGNVLTSGSAQTATPAQSQKTKAQLPNGGFKTADDGRLIISDKALRGQGGNDQSDDDSDSDASMAYGTVAKQPKVKRGMEDDSSDEDKLQQKLVPKRVRKGDDAMSMKSGKTTASSRYTAGGKGIHRQLTAGNSDAMSVKSGKSTSRPAGSEYGSKKAKGDMKKSGKLDPYAYIPLTRNNLNKRKRSMNSRKFKSVLRGAGAENGGAGGGRVSKKYK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12754-1", "uniprot_id": "RRP12_YEAST", "id": "Q12754-1", "name": "Ribosomal RNA-processing protein 12", "aln": "--------------MDQDKVAFLLELEDKLAKIRSQVNSKLENQ-------KHIAIILTAVEENIAGQ----------------------------------------------------------------------ATNDVSKNIVNYIISFMSLLD------------QAVDPSTHEIKDIQLASSSTYLLDLIFHYSPKVLLRSKFSEILTKIAPCITAEKAN--APLIRAAIGCLESLLIAQDAQAWNNTYDLNVTPKRGLQGILELSLDVRPKVRKRALDAVHAVLLNPPVAPT-----------------------AEHVAAVFVADFCDKQLAGILNDLSNLSNKQLKAQKTKEDINASVMRSLRLITSVVSTGQWPSSQIEPLCDVLLGVTKSSEQYLVSASFECFESMFKTMAETTISSGLAENKYLRVLDTIFALKPSNVDTLLTKSWIAVVIKGMSTYATHQPLKALRKIPGVFHIMCT-YLASETPEVYQAASQCLISILSESVKDDLLLYTPSVDEKVFKNVDEIISQIAKTFIDFLSIRYSHCSREILKILVAAFNKFRYRSNPHFLKSLKIVDTWRVNEEQFMDLRNEIELVIGASISAMGPEMILAEAPLNLD-NPSSERPGRAWLLPLIRDYTKNANLATFQNELAPYIKSFQSKFDKVPE--ESIQLRVFQTIVDQIWSTLPRFCELPMDLRESFTDEFASELSSLLYSEVELRTTICHALKVLAESNVSYAEESSSHNVLLLQRFPISEAQKNIEYLSTKSTNLLAVLFNVYTQTTPN-----ARSYILETIDQYLKITSKEDLEKTFNNVCGLLKNSMNEESSGNVNKEKKKPQLTATLLDLIICMITYLPVSSYSALFSMFSLTVNSADAL------------IQKRAYRIITKLS--ELKSGSTAVAQFISDIENVMVDSASSVQTSAKAARLTAIKTIVELLP--LDHLDFIVRTVAEVILSTKDVNEKSRETAFDTLICMGRKMNEPNGIIKLFQIPGYDPTTPDQSSSISEFFKIISAGLIGESQHMVSSSITGYACLVFEFKNELDSGILMDIYDTIELYLTSNSREIVKSAIGFTKVCVLGLPEELMRPKVPELLLKLLRWSHEHTGHFKAKVKHIIERLIRRFG--YDYIEANFPEEDRRLLTNIRKMRNRNKRK----------DEEVTTGVSDVAATKGSRFMSAFDEA----VYGSDEENDNGSDQEENVAGGKMKNGAKQFIVESGDNPLDLLDSQTLAHISSTRPKK----FNKNQNRARFNDDAFNFDSEGKLVVKGQPK------------PSTNVDDPLSAVT----------------------------------------------------SGINAYLEAVKS----------------GPVRGQRNKLKFRKNGK----DSDEFGDDDDGEKDSRLMRGRVNQGNK---IGKHNKKGPKFKSRKKL--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : * ..*: . : : *:. : * :.. *:: : :. .:: : . . . : . ** : :: * :* .:*:: : : . :* :.** :* ** .*. . :: ..:* :::. :**:** * ..: :: : .* *: .*.** :: . ::.:: * *:.. : : :.. .: ** : . . : : .:: : .:* . . . ::: ::. *.: * :*: *: :. * : :. .: : * :: ..:. : :: :.* . : :: . . *. : :: :: :. . : * : . :: .: .:: ::***::* ** *:**:*::*: .. : * * : . : . .. : . :::: : *:* :* ** * * : *. : .. ::* : ..* * .. .:: . :.*:*. ***:* * * :*:.* *:. : : : ::: . :.:*: .: . . . : *:::*.:: :: . . ::: :::* : . .: .** .: :: : ::: :.*.:* *:.. .: * : : : :. :. : *: * :: :: . :: . : . : : : : : *...:*. .::::.* . : : : :: :: : . : : : :: : :: :*. : .* : : .:: . * :: ::. *. : . : :: . : :: :. *: ::: * : .: :: : :. : .*: :*:*:: : . : . **: : .:: * ..:: *: : . ..:. :.: : . * : : : ", "identical_positions": 106, "similar_positions": 391, "identity": "7.11%" }, { "cls_id": "homologset.agr.SGD:S000005934", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7X1-1", "uniprot_id": "D4A7X1_RAT", "id": "D4A7X1-1", "name": "Small ribosomal subunit protein bS16m", "aln": "RQAGFELLPSLSLPPKCAVIKGVSCHAQHLPPPPPSTTSRNRFAVEAPKGRTRSQLTTFFCKAYHGGHLTIRLALGGCTNRPFYRIVAAHNKCPRDGRFVEQLGSYDPLPNSHG----------EKLVALNLDRIRHWIGCGAQLSKPMEKLLGLSGFFPLHPMMITNAERLRRKRAREVFLASQKADSEPQETEAS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CPX7-1", "uniprot_id": "RT16_MOUSE", "id": "Q9CPX7-1", "name": "Small ribosomal subunit protein bS16m", "aln": "----------------------------------------------------MVQLTTIFCKAYHGGHLTIRLALGGCTNRPFYRIVAAHNKCPRDGRFVEQLGSYDPLPNSHG----------EKLVALNLDRIRHWIGCGAHLSKPMEKLLGLSGFFPLHPMMITNAERLRRRRAREVLLASQKAESEAKETEAS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3D3-1", "uniprot_id": "RT16_HUMAN", "id": "Q9Y3D3-1", "name": "Small ribosomal subunit protein bS16m", "aln": "----------------------------------------------------MVHLTTLLCKAYRGGHLTIRLALGGCTNRPFYRIVAAHNKCPRDGRFVEQLGSYDPLPNSHG----------EKLVALNLDRIRHWIGCGAHLSKPMEKLLGLAGFFPLHPMMITNAERLRRKRAREVLLASQKTDAEATDTEATET", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V6Y3-1", "uniprot_id": "RT16_DROME", "id": "Q9V6Y3-1", "name": "Small ribosomal subunit protein bS16m", "aln": "---------------------------------------------------MSLSPASGIGRFYAKSAKIIRFVRLGCTNRPFYHIVVMERRKNQHQPVIEQVGSFDPLPNDYN----------ERLVALNTERIRYWLGKGAHLSTPAAELLGIAGLLPIHPRTYMTAWRNRR-TAAEAEASPEKAESTA--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02608-1", "uniprot_id": "RT16_YEAST", "id": "Q02608-1", "name": "Small ribosomal subunit protein bS16m", "aln": "---------------------------------------------------------------MTCGLVRIRLARFGRKNSPVYNIVVANSRKARDAKPIEVLGTYVPVPSPVTKRELKRGVVPIKDVKLDFDRTKYWIGVGAQPSETVTKLLRKAGILN-------DAWATSKNSNVNRKVVFERMETLE--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **:. * .* *.*.**. . : :. :* :*:: *:*. : * *: :* ::*:* **: * . :** :*:: * : : :: :: ", "identical_positions": 24, "similar_positions": 35, "identity": "12.06%" }, { "cls_id": "homologset.agr.SGD:S000005936", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJQ4-1", "uniprot_id": "SIR2_RAT", "id": "Q5RJQ4-1", "name": "NAD-dependent protein deacetylase sirtuin-2", "aln": "--------------------------------------------------------------------------------------------------MDFLRNLFTQTLGLGSQK--------ERLLDELTLEGVTRYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYANLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFIRLLKEKGLLLRCYTQNIDTLERVAGLEPQDLVEAHGTFYTSHCVNTSCGKEYTMSWMKEKIFSEATP---KCEKCQNVVKPDIVFFGENLPPRFFSCMQSD-------------FSKVDLLIIMGTSLQV---QPFASLISKAPLATPRLLINKEKTGQTDPFLGMMMGLGGGMDFDSKK-AYRDVAWLGDCDQGCLALADLLGWK-ELEDLVRREH--------------ANIDAQSGSQASNPSATVSPRKSPPPAKEAARTKEKEEH---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDQ8-1", "uniprot_id": "SIR2_MOUSE", "id": "Q8VDQ8-1", "name": "NAD-dependent protein deacetylase sirtuin-2", "aln": "-------------MAEPDPSDPLETQAGKVQEAQDSDSDTEG------------------------------------------------GATGGEAEMDFLRNLFTQTLGLGSQK--------ERLLDELTLEGVTRYMQSERCRKVICLVGAGISTSAGIPDFRSPSTGLYANLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFIRLLKEKGLLLRCYTQNIDTLERVAGLEPQDLVEAHGTFYTSHCVNTSCRKEYTMGWMKEKIFSEATP---RCEQCQSVVKPDIVFFGENLPSRFFSCMQSD-------------FSKVDLLIIMGTSLQV---QPFASLISKAPLATPRLLINKEKTGQTDPFLGMMMGLGGGMDFDSKK-AYRDVAWLGDCDQGCLALADLLGWKKELEDLVRREH--------------ANIDAQSGSQAPNPSTTISPGKSPPPAKEAARTKEKEEQQ--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IXJ6-1", "uniprot_id": "SIR2_HUMAN", "id": "Q8IXJ6-1", "name": "NAD-dependent protein deacetylase sirtuin-2", "aln": "-------------MAEPDPSHPLETQAGKVQEAQDSDSDSEG------------------------------------------------GAAGGEADMDFLRNLFSQTLSLGSQK--------ERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTP---KCEDCQSLVKPDIVFFGESLPARFFSCMQSD-------------FLKVDLLLVMGTSLQV---QPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKK-AYRDVAWLGECDQGCLALAELLGWKKELEDLVRREH--------------ASIDAQSGAGVPNPSTSASPKKSPPPAKDEARTTEREKPQ--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVK3-1", "uniprot_id": "SIR2_DANRE", "id": "Q7ZVK3-1", "name": "NAD-dependent protein deacetylase sirtuin-2", "aln": "-------------MSEEVSKRVEEEADTPGLEGQSDDSSDEG------------------------------------------------DASG-DTEMDFLRSLFSRTLGLSPG---------DKVLDELTLDSVARYILSGKCKNIICMVGAGISTSAGIPDFRSPGTGLYANLQKYNLPYPEAIFQIDYFKKHPEPFFALARELYPGQFKPTVYHYFIKMLKDKGLLRRCYSQNIDTLERVAGLEGEDLIEAHGTFHTSHCVSFLCRKEYSMDWMKNQIFSEEIP---KCDSCGSLVKPDIVFFGESLPSRFFTSMKAD-------------FPQCDLLIIMGTSLQV---QPFASLVSRVSNRCPRLLINMEKTGQSEFGMGLFS-FGGGMDFDSDK-AYRDVAHLSTCDDGCMTLAELLGWKKELEEMVKREH--------------ALIDSKDAKKTDKEASQSS--KS---AVAEAEKTDKTE----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7I7-1", "uniprot_id": "SIRT2_DROME", "id": "Q9I7I7-1", "name": "NAD-dependent protein deacetylase Sirt2", "aln": "-------------MGDIEVKK--EEQPTTPSNSSSSDDDEE----------------------------------------------------APDDTMDKVRRFFANTLHLGGSSDAKEEVKVEKVIPDLSFDGFAEHWRVHGFRKIVTMVGAGISTSAGIPDFRSPGSGLYSNLKKYELPHPTAIFDLDYFEKNPAPFFALAKELYPGSFIPTPAHYFIRLLNDKGLLQRHYTQNIDTLDRLTGLPEDKIIEAHGSFHTNHCIK--CRKEYDMDWMKAEIFADRLP---KCQKCQGVVKPDIVFFGENLPKRFYSSPEED-------------FQDCDLLIIMGTSLEV---QPFASLVWRPGPRCIRLLINRDAVGQASCVL-FMDPNTRSLLFDKPN-NTRDVAFLGDCDAGVMALAKALGWDQELQQLITSER--------------KKLSGSQNSEELQQGKEKP--QSDPDKMTSGDRDKKDASL--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8R104-1", "uniprot_id": "SIR3_MOUSE", "id": "Q8R104-1", "name": "NAD-dependent protein deacetylase sirtuin-3", "aln": "---------MALDPLGAVVLQSIMALSGR--------LALAA-----------------------------------------------LRLWGPGGGRRPISLCVGASGGFGGGG--------SSEK-KFSLQDVAELLRTRACSRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPKPFFMLAKELYPGHYRPNVTHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGTFVTATCTV--CRRSFPGEDIWADVMADRVP---RCPVCTGVVKPDIVFFGEQLPARFLLH-MAD-------------FALADLLLILGTSLEV---EPFASLSEAVQKSVPRLLINRDLVG----------------PFVLSP-RRKDVVQLGDVVHGVERLVDLLGWTQELLDLMQ------------------------RERGKLDGQDR------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5XWT5-1", "uniprot_id": "A0A8I5XWT5_RAT", "id": "A0A8I5XWT5-1", "name": "", "aln": "----MRSPDLAPQPISQSLTDGEAANTRHKPTLRHIGLTFRG-----------------------------------------------LAWEPITGGRRPISLSVGASGGFGCGG--------HSEK-KLSLQDVAELLRTRACSRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPKPFFTLAKELYPGHYRPNVAHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGSFVSATCTV--CRRSFPGEDIRADVMADRVP---RCPVCTGVVKPDIVFFGEQLPARFLLH-VAD-------------FALADLLLILGTSLEV---EPFASLSESVQKSVPRLLINRDLVG----------------SFALSP-RRKDVVQLGDVVQGVERLVDLLGWTQELQDLIQ------------------------RENGKLDGQDG------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NTG7-1", "uniprot_id": "SIR3_HUMAN", "id": "Q9NTG7-1", "name": "NAD-dependent protein deacetylase sirtuin-3, mitochondrial", "aln": "MAFWGWRAAAALRLWGRVVERVEAGGGVGPFQACGCRLVLGGRDDVSAGLRGSHGARGEPLDPARPLQRPPRPEVPRAFRRQPRAAAPSFFFSSIKGGRRSISFSVGASSVVGSGG--------SSDKGKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTV--CQRPFPGEDIRADVMADRVP---RCPVCTGVVKPDIVFFGEPLPQRFLLH-VVD-------------FPMADLLLILGTSLEV---EPFASLTEAVRSSVPRLLINRDLVG----------------PLAWHP-RSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQ------------------------RETGKLDGPDK------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LWD1-1", "uniprot_id": "Q1LWD1_DANRE", "id": "Q1LWD1-1", "name": "", "aln": "--MSKARLSRDRRAASVGVSRVTRSSMMSPQDCERSRAPDPG-------------------------------------------LLDELSLMSVSEQQASATRKGSSKPALSSPS--------GRSVSRGALETIGRLMKLGRVRNIVVVAGAGISTASGIPDFRTPGTGLYANLAKYDIPYPEAVFNIDYFSDNPHPFFSLAKELYPGHHRPNYVHYFIRMLHQKGLLLRMYTQNIDGLEKLCGIPDDKLVEAHGSFATAACHL--CYTPYPAEEAKQAIMNGSVP---ICTFCAGAVKPNVVFFGEDLPEKYFQH-AED-------------FPKADLLMIMGTSLKVGLIEPFASLINTVKSTVPRLLLNRDAVG----------------PFERRPLRRADYMELGDLSESVRKLAEILGWHTEIQTLMNSHE--------------NGLYSYISSSGENSGDSETDSMH-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53686-1", "uniprot_id": "HST2_YEAST", "id": "P53686-1", "name": "NAD-dependent protein deacetylase HST2", "aln": "-------------------------------------------------------------------------------------------------------------MSVSTAS------------TEMSVRKIAAHMKSNPNAKVIFMVGAGISTSCGIPDFRSPGTGLYHNLARLKLPYPEAVFDVDFFQSDPLPFYTLAKELYPGNFRPSKFHYLLKLFQDKDVLKRVYTQNIDTLERQAGVKDDLIIEAHGSFAHCHCIG--CGKVYPPQVFKSKLAEHPIKDFVKCDVCGELVKPAIVFFGEDLPDSFSETWLNDSEWLREKITTSGKHPQQPLVIVVGTSLAV---YPFASLPEEIPRKVKRVLCNLETVG----------------DFKANK-RPTDLIVHQYSDEFAEQLVEELGWQEDFEKILTAQGGMGDNSKEQLLEIVHDLENLSLDQSEHESADKKDKKLQRLNGHDSDEDGASNSSSSQKAAKE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :. . .:: :.******..******:*.:*** ** : .:*:* *:*:: :* .* **: **:***** . *. **:::::::* :* * *:**** *:: *: . ::****:* * * : : * * *** :***** ** : * . *::::**** * ***** *:* * : .* : * *.. *** :: :: . ", "identical_positions": 86, "similar_positions": 64, "identity": "17.2%" }, { "cls_id": "homologset.agr.SGD:S000005937", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BM75-1", "uniprot_id": "ARI5B_MOUSE", "id": "Q8BM75-1", "name": "AT-rich interactive domain-containing protein 5B", "aln": "-----------------------------------MEPNSLQWVGSPCGLHGPYIFYKAFQFHLEGKPRILSLGDFFFVR--------------------------------CTPKDPICIAELQLLWEERTSRQLLSSSKLYFLPEDTPQGRNSDHGEDEVIAVSEKVIVKLEDLVKWAHSDFSKWRCGLRATPVKT------------EAFGRNGQKEALLRYRQSTLNSGLNFKDVLKEKADLGEDEEETNVIVLSYPQYCRYRS-----MLKRIQDKPSSILTDQFALALGGIAVVSRNPQILYCRDTFDHPTLIENE-SVCDEFAPNLKGRPRKKKT-CPQRRDSFSGSKDPNNNCDGKVISKVKGEARSALTKPKN-NHNNCKKTSNEEKPKLSIGEECRADEQAFLVALYKYMKERKTPIERIPYLGFKQINLWTMFQAAQKLGGYETITARRQWKHIYDELGGNPGSTSAATCTRRHYERLILPYERFIKGEEDKPLPPIKPRKQENNTQENENKTKVSGNKRIKQEMAKNKKEKENTPKPQDTSE----------------VSSEQRKEEETLN-HKSAPEPLPAPEVKGKPEGHKDLGARAPVSRADPEKANETDQGSNSEKEAEEMGDKGLAPLLPSPPLPPEKDSAPTPGAGKQP-LASPSTQMDSKQEAKPCCFTESPEKDLQGAPFSSFSATKPPLTSQNEAEEEQLPATANYIANCTVKVDQLGSDDIHTALKQTPKVLVVQSFDMF-----KDKDLTGPMNENHGLNYTPLLYSRGNPGIMSPLAKKKLLSQVSGASLSSSYPYGSPPPLISKKKLIAREDLCSGLSQGHHSQS--SDHTAVSRPSVIQHVQSFKNKASEDRKSINDIFKHDKLS----RSDAHRCGFSKHQLGSLADSYILKQETQEGKDKLLEKRAVSHAHVPSFLADFYSSPHLHSLYRHTEHHLHNEQSSKYAA--RDAYQ-ESENGA-FLSHKHPEKIHVNYLASLHLQDKKVAAAEASTDDQPTDLSLPKNP---HKLTSKVLGLAHSTSGSQEIKGASQFQVVSNQSR--DCHPKACRVSPMTMSGPKKYPESLARS-GKPHQVRLENFR--KMEGMVHPILHRKMSPQNIGAARPIKRSLEDLDLVIAGKKARAVSPLDPA--KEASGKEKASEQESEGNKGAYGG--HSGAASEGHKLPLSTPIFPGLYSGSLCN------SGLNSRLPAGYSHSLQYLKNQTVLSPLMQPLAFHSLVMQRGIFTSPTNSQQLYRHLAAATPVGSSYGDLLHNSIYPLAGINPQAAFPSSQLSSVHPSTKL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AEL5-1", "uniprot_id": "A0A8I6AEL5_RAT", "id": "A0A8I6AEL5-1", "name": "AT-rich interactive domain-containing protein 5B", "aln": "-----------------------------------MEPNSLQWVGSPCGLHGPYIFYKAFQFHLEGKPRILSLGDFFFVR--------------------------------CTPKDPICIAELQLLWEERTSRQLLSSSKLYFLPEDTPQGRNSDHGEDEVIAVSEKVIVKLEDLVKWAHSDFSKWRCGLRATPVKT------------EGFGRNGQKEALLRYRQSTLNSGLNFKDVLKEKADLGEDEEENNVIVLSYPQYCRYRS-----MLKRIQDKPSSILTDQFALALGGIAVVSRNPQILYCRDTFDHPTLIENE-SVCDEFAPNLKGRPRKKKT-CPQRRDSFSGSKDPNNNCDGKVISKVKGEARSALTKPKN-NHNNCKKSSSEEKPKLSIGEECRADEQAFLVALYKYMKERKTPIERIPYLGFKQINLWTMFQAAQKLGGYETITARRQWKHIYDELGGNPGSTSAATCTRRHYERLILPYERFIKGEEDKPLPPIKPRKQENNAQENENKTKVSGNKRIKQEMAKNKKEKENTPKPQDPSE----------------VSSEQRKEEETLS-QKSVPEPLPAPEVKKKPEGHKDLVVRAPVSRADPEKGNETDQGSNCEKEAEEVGDKGLAPLLPSPPLPPEKGSAPTPGAGKQP-LASPSAQMDSKQEAKPCCFPESPENDLQGAPFSSLPTTEQPLAVQPEAEEEKLPAMANYIANCTVKVDQLGSDDIHTALKQTPKVLVVQSFDMF-----KDKDLTGPMNENHGLNYTPLLYSRGNPGIMSPLAKKKLLSQVSGASLSSSYPYGSPPPLISKKKLIARDDQ----SQAHHSQS--SDHMAISRPSVIQHVQSFKNKASEDRKSINDIFKHDKLS----RSDAHRCGFSKHQLGSLADSYILKQEAQESKDKLLEKRAVSHAHVPSLLADFYSSPHLHSLYRHTEHHLHNEQSAKYAA--RDVYQ-ESENGA-FLSHKHPEKIHVNYLASLHLQDKKLAAAEASTDEQPTDLSLPKNP---HKLTSKVLGLAHSASGSQEIKGTSQFQVISSQSR--DCHPKACRVSPMTMSAPKKYPESLARS-GKPHHVRLENFR--KMEGMVHPILHRKMSPQNIGAARPIKRSLEDLDLVIAGKKARAVSPLDPA--KEASGKEKASEQESEGNKAAYSG--HSGAASEGHKVPLSSPIFPGLYSGSLCN------SGLNSRLPAGYSHSLQYLKNQTVLSPLMQPLAFHSLVMQRGIFTSPTNSQQLYRHLAAATPVGSSYGDLLHNSIYPLAAINPQAAFPSSQLSSVHPSTKL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14865-1", "uniprot_id": "ARI5B_HUMAN", "id": "Q14865-1", "name": "AT-rich interactive domain-containing protein 5B", "aln": "-----------------------------------MEPNSLQWVGSPCGLHGPYIFYKAFQFHLEGKPRILSLGDFFFVR--------------------------------CTPKDPICIAELQLLWEERTSRQLLSSSKLYFLPEDTPQGRNSDHGEDEVIAVSEKVIVKLEDLVKWVHSDFSKWRCGFHAGPVKT------------EALGRNGQKEALLKYRQSTLNSGLNFKDVLKEKADLGEDEEETNVIVLSYPQYCRYRS-----MLKRIQDKPSSILTDQFALALGGIAVVSRNPQILYCRDTFDHPTLIENE-SICDEFAPNLKGRPRKKKP-CPQRRDSFSGVKDSNNNSDGKAVAKVKCEARSALTKPKN-NHN-CKKVSNEEKPKVAIGEECRADEQAFLVALYKYMKERKTPIERIPYLGFKQINLWTMFQAAQKLGGYETITARRQWKHIYDELGGNPGSTSAATCTRRHYERLILPYERFIKGEEDKPLPPIKPRKQENSSQENENKTKVSGTKRIKHEIPKSKKEKENAPKPQDAAE----------------VSSEQEKEQETLISQKSIPEPLPAADMKKKIEGYQEFSAKPLASRVDPEKDNETDQGSNSEKVAEEAGEKGPTPPLPSAPLAPEKDSALVPGASKQP-LTSPSALVDSKQESKLCCFTESPESEPQEASFPSFPTTQPPLANQNETEDDKLPAMADYIANCTVKVDQLGSDDIHNALKQTPKVLVVQSFDMF-----KDKDLTGPMNENHGLNYTPLLYSRGNPGIMSPLAKKKLLSQVSGASLSSSYPYGSPPPLISKKKLIARDDLCSSLSQTHHGQS--TDHMAVSRPSVIQHVQSFRSKPSEERKTINDIFKHEKLS----RSDPHRCSFSKHHLNPLADSYVLKQEIQEGKDKLLEKRALPHSHMPSFLADFYSSPHLHSLYRHTEHHLHNEQTSKYPS--RDMYR-ESENSS-FPSHRHQEKLHVNYLTSLHLQDKKSAAAEAPTDDQPTDLSLPKNP---HKPTGKVLGLAHSTTGPQESKGISQFQVLGSQSR--DCHPKACRVSPMTMSGPKKYPESLSRS-GKPHHVRLENFR--KMEGMVHPILHRKMSPQNIGAARPIKRSLEDLDLVIAGKKARAVSPLDPS--KEVSGKEKASEQESEGSKAAHGG--HSGGGSEGHKLPLSSPIFPGLYSGSLCN------SGLNSRLPAGYSHSLQYLKNQTVLSPLMQPLAFHSLVMQRGIFTSPTNSQQLYRHLAAATPVGSSYGDLLHNSIYPLAAINPQAAFPSSQLSSVHPSTKL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F888-1", "uniprot_id": "ARI5B_DANRE", "id": "E7F888-1", "name": "AT-rich interactive domain-containing protein 5B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVSDLRSWKKGLQAVPLKPG---------VLKELGKNGQREALHKYRESTLNSGLNFKDVLKEKAELGEDADDKKVLVLSYPQYCRYRS-----IIARLRERPSSLLTDHVVLALGGIASLTNSTQILYCRDTFEHPTLVENE-SVCDEFAPNLKGRPRKKKLSISQRRDSQSGGARESNGVEGKTLVKMRADSKSGVSKPRNPSTGSCKRVQSENKPKGDGGDECRTDEQAFLVALYKYMKERKTPIERIPYLGFKQINLWTMFQAAQKLGGYEVITARRQWKNVYDELGGNPGSTSAATCTRRHYERLILPYERFTKGEEDKPLPPAKPRKQEGSVQESIIKAKMMPIKRPKDEQKTPRGDKDASAKVLELGM----------------EDMEELQE-------KQNSQQLQAPTQTDR-------DPNSPLTEDDEGVLVIKDEDQPVLHNAYEHANGGLLPSLP-------QDGAQLKSEDCDA-FPVAAVPLHHGHP-----LPNSHTSDQWKHGILEYKVPPSALAN---------------VEQSRPKEGQNQVVMVLPTLQQKP----VTSPEIP-----PER-VEPLKKEESCFNFNPLLYPRGNPGIMSPLAKKKMLSQVSGTGLLNNYPYGPPPPLVSRRLSSSGTEVSSAGQSSSQVSSSVETSIVIKRPSVIQHAQSFKSRGSEDRRSSTEGSQKDGCS----EGEP-----VHHSQTLIREPYLKRVDPHSSMEKSAEMPRP--GQAPSFLSEFYSSPHLHNLCRQTEHHLSKEQISKYLS--RDVYTRDSETAQGFPPSQHPDNVGLNFSARLSQKEKG-PPPERVTEEQPTDLSLPKSSPLKLPLSTSTLGGIPHAAIQQDIKNSPHFQAGNSQSSSVDYHPRACRVPPMTVSASKKVTESHSKVLEKTPNSRGEESMGFKIDEMSRPILSTKSSPQNICTARPLKRNIEDLENGPTEKKIRAVTPLHCSTQRDLPGKPRTPEADSESVKPAEPAVHINSYTSEGHKIPLHSHLFQGLYPGTFVSQVQDMCESLGSHVTPSYSHPLQYLKNQAVLSPLMPPFAIHSLMMQRQFLAA--NPAHMYRH-----QVGTSYGDILHPGLYPMSALHPQPAFSPPQLSSVHPSTKLS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09547-1", "uniprot_id": "SWI1_YEAST", "id": "P09547-1", "name": "SWI/SNF chromatin-remodeling complex subunit SWI1", "aln": "MDFFNLNNNNNNNNTTTTTTTTNNNNTNNNNTNNNNNPANNTNNNNSTGHSSNTNNNTNNNNTNTGASGVDDFQNFFDPKPFDQNLDSNNNNSNSNNNDNNNSNTVASSTNFTSPTAVVNNAAPANVTGGKAANFIQNQSPQFNSPYDSNNSNTNLNSLSPQAILAKNSIIDSSNLPLQAQQQLYGGNNNNNSTGIANDNVITPHFITNVQSISQNSSSSTPNTNSNSTPNANQQFLPFNNSASNNGNLTSNQLISNYAASNSMDRSSSASNEFVPNTSDNNNNSNNHNMRNNSNNKTSNNNNVTAVPAATPANTNNSTSNANTVFSERAAMFAALQQKQQQRFQALQQQQQQQQNQQQQNQQPQQQQQQQQNPKFLQSQRQQQQRSILQSLNPALQEKISTELNNKQYELFMKSLIENCKKRNMPLQSIPEIGNRKINLFYLYMLVQKFGGADQVTRTQQWSMVAQRLQ-----ISDYQQLESIYFRILLPYERHMISQEGIKETQAKRIFLQQFLQELLKKVQQQQQAAALANANNNINSASSAPTPAAPGASVPATAAPGTEAGIVPVSANTPKSLNSNININVNNNNIGQQQVKKPRKQRVKKKTKKELELERKEREDFQKRQQKLLEDQQRQQKLLLETKLRQQYEIELKKLPKVYKRSIVRNYKPLINRLKHYNGYDINYISKIGEKIDSNKPIFLFAPELGAINLHALSMSLQSKNLGEINTALNTLLVTSADSNLKISLVKYPELLDSLAILGMNLLSNLSQNVVPYHRNTSDYYYEDAGSNQYYVTQHDKMVDKIFEKVNNNATLTPNDSNDEKVTILVDSLTGNQLPTPTPTEMEPDLDTECFISMQSTSPAVKQWDLLPEPIRFLPNQFPLKIHRTPYLTSLKKIKDEIDDPFTKINTRGAEDPKVLINDQLSTISMILRNISFSDNNSRIMSRNFYLKRFISDLLWLVLIHPENFTCNRKILNFKKDLVIVLSNISHLLEIASSIDCLLILILVISFGQPKLNPMASSSSFGSESLTFNEFQLQWGKYQTFGVDILAKLFSLEKPNLNYFKSILLNKNTGNNLYDRNSNNNHKDKKLLRRLLNLYNDN--NKNNNNRHNLLNDVVSFLFSAIPLQQVLSQSADPSLLIDQFSPVISQSLTSILVIVQKILPLS--NEVFEISENNSDSNSNNNGNKDSSFNFNKNLPFVWLSSEENIGSGLLKLSEIILNINNSTSKNTLLQQQNYSKVLLPSINISCVQLIKCLVEKSICFEN----CLNNDPEILKKIASIPNLFPTDLEIFQLFTNPSVDIQIINQYQLLYNLKNDILTNLE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: . . .: : : :.:*.. .: :** *:. :* . :. :: *: .: : : .: * :: . :. .. ..:. .. : ... : . . : . .* :: .* *. : . :*:: ::. . .: : : : : . : . :: . : . : : . : : *: :* : *:*: *:: ** :* ::***: :: .**:** : :* :**. : :.* * . * *::*****. .:*. . * : ** *.: : . . . :.. . . : :. : : : . . .. . . . . . * : . . :. : :.: . : .: : :* : * : .: : .: : : . :..* : . ..: * . . . .:: . . .: . *:* * . .: . : : : : :. : : . . . : : :** . .: .* . * : : :. .. : . : : : . :. . .*:: : :. :. : . .:. : : : .. . :: : : : . .: :. : .* : .*. .: :.: :. : . . * : .: . . .... : . . :. : ** : . .: : : . : *: :. :*: ::. . * .: :: : .: :::: * :: : . . *:* ", "identical_positions": 67, "similar_positions": 320, "identity": "5.05%" }, { "cls_id": "homologset.agr.SGD:S000005941", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91ZX6-1", "uniprot_id": "SENP2_MOUSE", "id": "Q91ZX6-1", "name": "Sentrin-specific protease 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYRWLAKVLGTILRLCERPAPGARALLKRRR-SSSTLFSTAVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVSSACNGTRNVAPSGEVFSNSSSCELMSSGSCSSMLKLGNKSPNGISDYPKIRVTVTRDQPRRVLPSFGFTLKSEGYNRRPSGRRHSKSNPESSLTWKPQEQGVTEMISEEGGKGV------RRPHCTVEEGVQKDEREKYRKLLERLKEGAHG------------------------------------------------------------------------------------------------------------------------STFPPTVSHHSSQRIQMDTLKTKGWVE------------EQNHGVRTTHFVPKQYRVVETRGPLCSMRSEKRYSKGK------------------------------------------------------------------------------------------ADTEKVVGLRFEKEGTRGHQMEPDLSEEVSARLRLGSGSNGLLR--RKISVLEIKEKNFP----SKEKDRRTEDLFEFTEDMEKEISNALG---HGPPDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYMNLLVERSKKQG--YPALHAFSTFFYPKLKSGGYQAVKRWTKG--VNLFEQELVLVPIHRK-VHWSLVVMDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNTDLNLLEWTHYSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9EQE1-1", "uniprot_id": "SENP2_RAT", "id": "Q9EQE1-1", "name": "Sentrin-specific protease 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYRWLTKVLGTILRLCERPAPGARALLKRRR-SSSSLFSTAVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVSSACNGTRNVAPSGEVFSNSPSCELTTSGSCSSMLKLGNKSPNGISDYPKIRVTVARDQPRRVLPSFGFTLKSEGYNRRPSGRRHSKSNPESSLPWKPQEQGVTEMISEEGGKGA------RRPHCTVEEGVQKDEREKYLKLLERLKEGAHG------------------------------------------------------------------------------------------------------------------------STFPPAVSHHSSQRTQMDTLKTKGWME------------EQNHGVRTTHLVPKQYRVVETRGPLCSVRSEKRYSKGK------------------------------------------------------------------------------------------ADTEKVVGLRFEKDGTRGHQLEPDLSEEVSARLRLGSGSNGLLR--RKISVLEAKEKNFP----SKEKDRRTEDLFELTEDMEKEISNALG---HGPPDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYMNLLVERSKKQG--YPALHALSTFFYPKLKSGGYQAVKRWTKG--VNLFDQELVLVPIHRK-VHWSLVVMDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNTDLNLLEWTHYSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HC62-1", "uniprot_id": "SENP2_HUMAN", "id": "Q9HC62-1", "name": "Sentrin-specific protease 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYRWLVRILGTIFRFCDRSVPPARALLKRRR-SDSTLFST-VDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSSSCELTGSGSWNNMLKLGNKSPNGISDYPKIRVTVTRDQPRRVLPSFGFTLNSEGCNRRPGGRRHSKGNPESSLMWKPQEQAVTEMISEESGKGL------RRPHCTVEEGVQKEEREKYRKLLERLKESGHGN-----------------------------------------------------------------------------------------------------------------------SVCPVTSNYHSSQRSQMDTLKTKGWGE------------EQNHGVKTTQFVPKQYRLVETRGPLCSLRSEKRCSKGKI-----------------------------------------------------------------------------------------TDTETMVGIRFENESRRGYQLEPDLSEEVSARLRLGSGSNGLLR--RKVSIIETKEKNCS----GKERDRRTDDLLELTEDMEKEISNALG---HGPQDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYMNLLVERNKKQG--YPALHVFSTFFYPKLKSGGYQAVKRWTKG--VNLFEQEIILVPIHRK-VHWSLVVIDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3X9P9-1", "uniprot_id": "G3X9P9_MOUSE", "id": "G3X9P9-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWQPKLPGLEM----KPEASAIGQTRKYH-DES---GTEIESEALGQEPKRK---------------------------------CQ-----DGSGMVFK-----------------EPGKAQKKTSQEPQDL--ELPREQP------------SKGQVRKPQGK-TPKQLKPLELTEGPPEQAVTGRKPADGGKGH------KRPYSVMEENEQSPQKEKYGRLLQHLQCDQDV-----------------------------------------------------------------------------------------------------------------------------RSDQHRPHPILTNTWKIKGGES------------GDSHGSERIQSNREPSTVAALKECLSPEGREKCCSEEK--------------------------------------------------------------------------------------------CVTEKKGCVKGEGRRGNSLEPDLPETWAQIILDSGRGNSLLP--NKVAVLAAEKKPIT----DQGKGRKMDQILDISEDMEKEIENALG---PGPQEEILSSRFKLQISRGDIQTLENGQWLNDEVINFYMNLLVERNENQG--YPALHVFSTFFYPKLKHSGYSSVKRWTRG--INLFEKELILVPIHQR-VHWSLVVIDLRKRSIVYLDSMGQTGKSICETIFQYLQNESKTRRNIELDPLEWKQCSVTSEEIPLQLNGSDCGVFTCKYADYIARDQPVTFSQQHMPTFRKRMVWEILHSQLL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z741-1", "uniprot_id": "D3Z741_MOUSE", "id": "D3Z741-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWQPKQPGLEM----KPEASGIGQKRKYH-DES---VTEIESEPLGQEPKRK---------------------------------CQ-----DGTGMVFK-----------------EPG-------KEPRDQ--ELPREHP------------SKGQVRKPQGK-TPKQLEPLELTEGSPEQVVTGRKPADGGKGH------KRPYSVMEENEQSPQKEKYGRLLQHLQCDQDV-----------------------------------------------------------------------------------------------------------------------------SSDPHRPHPFLTNTWKIKGGES------------EDSRGSERTQSDREPSTVVALKECLSPEEREKCCSEEK--------------------------------------------------------------------------------------------CVTEKKDCIKGEGRRGNSLEPDLPGTQAQIILDSGKGNSLFP--NKVAVLAAEKKPIT----DRGKGREMDQILDITEDMEKEIENALG---PGPQEEILSSRFKLQISRGDIQTLENGQWLNDEVINFYMNLLVERNENQG--YPALHVFSTFFYPKLKHGGYSSVKRWTRG--INLFEKELILVPIHQR-VHWSLVVIDLRKRSIVYLDSMGQTGKSICETIFQYLQNESKTRRNVELDPLEWKQYSVTSEEIPLQLNGSDCGMFTCKYADYIARDQPVTFSQQHMPTFRKRMVWEILHSQLL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PXF3-1", "uniprot_id": "E9PXF3_MOUSE", "id": "E9PXF3-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEK----KPEASGKGQKRKHQ-DES---RIEIDSEALGQDPKRK---------------------------------CQ-----DGTTMVFK-----------------VPGKAQKMTPQEPPDL--ELAIEQF------------SKGQVRKSQGE-TPNQPKPLELTEGPPEQVVTGRAPADSGKGH------KRPYSAMEENEQIPQKEKKRRLLQNLK------------------------------------------------------------------------------------------------------------------------------------------LILIKAGKIKGGES------------EDSHGSETTLRDPEPSTVVALKECLSPDEREKCCFEET--------------------------------------------------------------------------------------------SVTEKKGCVKVEGRRGNSLEP---GTQAQIILDSSRGNSLLP--NKMAVLAAQKKPLR----DHEKHREMDQILDITEDMEKEIENALG---PGPQEEILSSRFKLLITRGDIQTLKNGQWLNDEVINFYMNLLVERNENQG--YPALHVFSTFFYPKLKHSGYSSVKRWTRG--INLFEKELILVPIHQR-LHWSLVVIDLRKQSIAYFDSIGQTGKSICETIFQYLQNESKTRRNIELDPLEWKQYSMASEEIPLQMNGSDCGMFTCKYADYIARDQPVTFSQQHMPTFRKRMVWEILHSQLL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RCW3-1", "uniprot_id": "M0RCW3_RAT", "id": "M0RCW3-1", "name": "Ubiquitin-like protease family profile domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWQPKHPGVGM----KPEASGQHRKQKHL-DQN---GTETESEALGQGPSRN---------------------------------CQ-----DGAQMVFQ-----------------KPGKAQKKTRQEHQDQ--KLKKEQP------------GKGQGQKIQDE-GSGNIKPLE---GLPDQAVVEKS-AEGGKCR------KRPYSVLQEKPQSPQNEKHARSLEHLQGGHPV-----------------------------------------------------------------------------------------------------------------------------RSDPHRPHPTFSDTSNNKGGMP------------GHPHGSETAQGDGQSST-----EVLSTK-REKRCAEEK--------------------------------------------------------------------------------------------CVR------------GNSLEHGLRGTENANILDSG-GGRLLP--DKVAVVAGEKNALP----EQEN----NQEKEFTKEMEKEVEKALG---PGAQEEILSMGFKLKITRGDMQTLKNGQWLNDEVINFYMNLLVQRNENPG--YPALHAFSTFFYAKLKHSGYNSVKRWTRG--INLFEKELILVPIHQR-VHWSLVVIDLRKRSIVYLDSMGQTGKNICETIFHYLQNESKTRRNMELDPVEWKQYSLTSQEIPQQLNGSDCGMFTCKYADYISRDQPVTFSQQHMPLFRKRMVWEILHSHLL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59110-1", "uniprot_id": "SENP1_MOUSE", "id": "P59110-1", "name": "Sentrin-specific protease 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDDTADGVKMDAGEVTLVNHGSTFRTHRPPQSGFPEEQLLLSDQQSLPFRQGTLDGSFTCSTRSPAYRPDYHSDNPSSDSFLGSGDVRTFGQSANGQWRN--------------STPASGSAPQKPRNSRSLCLETRKTSSG-------LSNTFVGKSNHHCHMSAYEKSFPIKPAPSPSWSGSCRRSLLSPKKTQ------RRHFSTAEETVQEEEKEIYRQLLQMVTGKQFCV-----------------------------------------------------------------------------------------------------------------------AKPTTHFPLRLSRCLSSNKNSLKDSLLRNGNSCASHVIGSDTSSSGSASILTAQEQLSHSAHSLSSGTPDVAFGSKDS----DPHHHLAAPHQPNSLPASNTQSEGSDSVILLKVKESQTPAS--------------------------SPTFFQAELWIKELTSVYDSRARERLRRIEEQKALALQLQNQRLQEQEHAVLDSVELHLRVPLEKEIPVTAAQETRKK----SHQLTDSEDEFPEITEEMEKEIKNVFR---NGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEKG--FPSVHAFNTFFFTKLKTAGYQAVKRWTKK--VDVFSVDILLVPIHLG-VHWCLAVVDFRRKSITYYDSMGGINNEACRILLQYLKQESVDKKRKEFDTNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K1R8-1", "uniprot_id": "A0A0G2K1R8_RAT", "id": "A0A0G2K1R8-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRNPLTATVFLPGSSPLGFCIFTTVSDVKRPEMEDTADGVKMDAGEVTLVNHSSAFRAHLLPHSGFPEDQLALSDQQILPFRQGTLHRAFTGSTSSAAYNPDYHSDNPSSDSFLGSGDIRTFGQSANGQWRN--------------STPASGSALQKPRNSRSLYLETRKTSSG-------LSNTFVGKSNHHCHVSAYEKSFPIKPAPSPSWSGSCRRSLLSPKKTQ------RRHFSTAEETVQEEEKEIYRQLLQMVTGKQFSV-----------------------------------------------------------------------------------------------------------------------AKPTTHFPLHLSRCLSSNKNSLKDSLLRNGNSCASHVIGSDTSSSGSASILTAQEQLSHSAHSLISGTPDVAFGSKDS----ALHHHLSAPHQPDSLPASNPQSEGSDSVILLKVKESQTPASRYLSPLKRSTCPYIIPYSAVTDLLSSSPTFFQAELWIKELTSVYDSRARERLRQIEEQKALALQLQNQRLQEQEHAVLDSVELHLRVPLEKEVPVTAAQETRKK----SHQLTDSEDEFPEITEEMEKEIKNVFR---NGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEKG--FPSVHAFNTFFFTKLKAAGYQAVKRWTKK--VDVFSVDILLVPIHLG-VHWCLAVVDFRKKSVTYYDSMGGVNNEACRILLQYLKQESVDKKRKEFDTNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P0U3-1", "uniprot_id": "SENP1_HUMAN", "id": "Q9P0U3-1", "name": "Sentrin-specific protease 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDDIADRMRMDAGEVTLVNHNSVFKTHLLPQTGFPEDQLSLSDQQILSSRQGHLDRSFTCSTRSAAYNPSYYSDNPSSDSFLGSGDLRTFGQSANGQWRN--------------STPSSSSSLQKSRNSRSLYLETRKTSSG-------LSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQ------RRHVSTAEETVQEEEREIYRQLLQMVTGKQFTI-----------------------------------------------------------------------------------------------------------------------AKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNSCASQIIGSDTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGSKDSGTLHHPHHHHSVPHQPDNLAASNTQSEGSDSVILLKVKDSQTPTP--------------------------SSTFFQAELWIKELTSVYDSRARERLRQIEEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQETQKK----GHKLTDSEDEFPEITEEMEKEIKNVFR---NGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEKG--LPSVHAFNTFFFTKLKTAGYQAVKRWTKK--VDVFSVDILLVPIHLG-VHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9EP97-1", "uniprot_id": "SENP3_MOUSE", "id": "Q9EP97-1", "name": "Sentrin-specific protease 3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKETIQGTGSWGPEPPGPGT--TYSNPRRERLRWPLPPKPRLKSGG-GFGPDPGSGTTVPTRRLPAPRP----SFDASASEEEEEEEEED----EEEVAAWRL-----------------PPRWGQLGASQRSRALRPSHRKTCSQRRRRAMRAFQMLLYSKSTSLTFHWKLWGRHRGRRRNLAHPKNHLSPQEGGATP------QVPSPCCRFDSPRGLPPPRLGLLGALMAEDG---------------------------------------------------------------------------------------------------------------------MRGSPPVPSGPPMEEDGLRWTPKSPLDPDSGLLSCTLPNGFGGLSGPEGERSLAPPDASILISNVCSIGDHVAQELFQSSDL------------------------------------------------------------------------------------GIAEEADRTGEKAGQHSPLR-------------EEHVTCVQSILDEFLQTYGSLIPLSTDEVVEK----LEDIFQQEFSTPSRKSLVLQLIQSYQRMPGNAMVRGFRVSYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEK------VHFFNSFFYDKLRTKGYDGVKRWTKN--VDIFNKELLLIPIHLE-VHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDF-HQGWKGYFKMN--VARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPKLRRQIYKELCHCKLTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LKC6-1", "uniprot_id": "A0ABK0LKC6_RAT", "id": "A0ABK0LKC6-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKETIQGTGSWGPEPPGPGT--TYSNPRRERLRWPLPPKPRLKSGG-GFGPDPGSGTTVPTRRLPGPRP----SFDASASEEEEEEEEED----EEEVAAWRL-----------------PPRWGQLGTSQRPRALRPSHRKTCSQRRRRAMRAFQMLLYSKSTSLTFHWKLWGRHRGRRRNLAHPKNHLSPQEGGATP------QVPSPCCRFDSPRGLPPPRLGLLGALMAEDG---------------------------------------------------------------------------------------------------------------------MRGSPPVPSGPPMEEDGLRWTPKSPLDPDSGLLSCTLPNGFGGLSGPEGERSLAPPDASILISNVCSIGDHVAQELFQSSDL------------------------------------------------------------------------------------GTAEEADRPGEKAGQHSPLR-------------EEHVTCVQSILDEFLQTYGSLIPLSTDEVVEK----LEDIFQQEFSTPSRKSLVLQLIQSYQRMPGNAMVRGFRVSYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEK------VHFFNSFFYDKLRTKGYDGVKRWTKN--VDIFNKELLLIPIHLE-VHWSLVSVDVRRRTITYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDF-HQGWKGYFKMN--VARQNNDSDCGAFVLQ---VFILETSFLY----MPIPGEQMAVRM-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H4L4-1", "uniprot_id": "SENP3_HUMAN", "id": "Q9H4L4-1", "name": "Sentrin-specific protease 3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKETIQGTGSWGPEPPGPGIPPAYSSPRRERLRWPPPPKPRLKSGG-GFGPDPGSGTTVPARRLPVPRP----SFDASASEEEEEEEEEEDEDEEEEVAAWRL-----------------PPRWSQLGTSQRPRPSRPTHRKTCSQRRRRAMRAFRMLLYSKSTSLTFHWKLWGRHRGRRRGLAHPKNHLSPQQGGATP------QVPSPCCRFDSPRGPPPPRLGLLGALMAEDG---------------------------------------------------------------------------------------------------------------------VRGSPPVPSGPPMEEDGLRWTPKSPLDPDSGLLSCTLPNGFGGQSGPEGERSLAPPDASILISNVCSIGDHVAQELFQGSDL------------------------------------------------------------------------------------GMAEEAERPGEKAGQHSPLR-------------EEHVTCVQSILDEFLQTYGSLIPLSTDEVVEK----LEDIFQQEFSTPSRKGLVLQLIQSYQRMPGNAMVRGFRVAYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEK------VHFFNSFFYDKLRTKGYDGVKRWTKN--VDIFNKELLLIPIHLE-VHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDF-HQGWKGYFKMN--VARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPKLRRQIYKELCHCKLTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NCS7-1", "uniprot_id": "A0A8M1NCS7_DANRE", "id": "A0A8M1NCS7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRDSGGSLSQN-------RWQGELSLTVSQEASSVAGMGGG--LMDPNSPPNATSPIHLKLSNRE---RVWSEDYIEPVELDEEAGFDENEDDMEEDEE-----------------EDEE-ERDEEDIDSECAPWEEKDDLEDWQMPFESQPHVMLANTYQQQVTLTEG-EAKSQARDFSENPFQMRLH-GLRQQ------RLNRWR-RLRSSARLRNRLVQNWKTWRQQAQ---------------------------------------------------------------------------------------------------------------------WVGTLGYRRARRWRQYSLYASK--KREKGCDTKGSTLRG-LVTTSERETENQFSAYNGYGDSQSVSSLSG-------VREYL------------------------------------------------------------------------------------SMPMKPTIQR----IEMTLT-------------EEHKAYVHGLIEDDLRKYGSLIPVHADDIAEQ----LQSIFNEDFSQTHRKMAVQHLIQSYQRSSGTAMVKGFRVNYKRHVLTMDDLSTLYGQNWLNDQVMNMYGDLVMDSVPEK------VHFFNSFFYDKLRTKGYDGVKRWTKN--VDIFQKDLLLIPIHLE-VHWSLVSVDIKRRSITYFDSQRTLNRRCPKHIFKYLQAEAMIKEKRDF-LTGWKGFFKMN--VGRQNNDSDCGAFVLQYCKCLALGQPFSFSQQDMPKLRRMMYKELCHCKLSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2BEN4-1", "uniprot_id": "A2BEN4_DANRE", "id": "A2BEN4-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRDSGSSLAQT-------HWSNELTLTAGQEGAGGGGAIGGGHLMNPAMAQHAPSPAHFKLGRREEDVRMWGADYTVPEVEDEE------EEEEEEEED-----------------DVEM-ESGEDLEDQGIFHLQDQGDDKDWGTPEHSQ-------VAEMDVRVTD---------DFTHCMAQRRPR-LLKVR------RLARLPNRGRRYLSIRFRLAQHWRTWRQRAK---------------------------------------------------------------------------------------------------------------------WAGTMGYRRVRRCHRRRYFGSQHFQRPPGRSLLNGDPEGRLQGTEISDSCSTNGALKGRDGLH--GAVLG-------EREGR------------------------------------------------------------------------------------ASPTNVQSQREKASLQNQLS-------------SEHISCVQGILDEFLQQYGSLIPIHVDEVVEK----LQEIFTESFSSPHRKIMVQHLMQSYQRMSGSAMMRGFRVNYKRHVLVMDDLTTLYGQNWLNDQVMNMYGDLVMDAAPEK------VHFFNSFFYDKLRTKGYEGVKRWTKN--VDIFQKKFLLIPIHLE-VHWSLVCVNVPQRSVTYFDSQRTLNRRCPKHIAKYLQAEAIKREQKDF-YTGWKGFFKMN--VARQNNDSDCGAFVLQYCKCLALEQPFSFGQQDMPKLRRQMYKELCHCKLSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4A2S8-1", "uniprot_id": "D4A2S8_RAT", "id": "D4A2S8-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKKQKKILWKKGIHLAFSEKWNAGFGGFKKLYFPQNLCFLKAKLGRPVVWHRQSKHFQCNKRGLHIQKTWTQDVPLCSKTKSGVATQNVSSLYAKVKRKDTKHFISSSRSLLKLQADKLLSSAKNLGREYCREKSLLKAVTGLSANTVL-----------------GKANGHKPSTDPQASDFPMKFNGESQSPSDSGKTVV-LNKHRKR-VCYGCYQGLEHHRNRRPLIPKKFQPNQHRRVKVS-LMMYEKLSMIRFRYRIFRSQHFRTKSRVCKLRKAQRSWVQKVTGDHQENFRDNNTEGGDCSPVPSLEPKDP-CRCQPYFPDMDSSAVVKGKNCHVPDGHTKESPALDKEHGLDAAFPDQQNGSTTYTWDQP-SSSPKWECTEQIHEIPLMGHPSSDNFTPGTERALMTLGQESGTSAVSDDGVKLSVSGADESVSSVDGPVSEEPAQNEN-FQMEEDGSLRQNILSSKLLDHPYC------------------------------------------------------------------------------------KSPLDAPLVCSELKVENQVAGGKSGQTASPVDDEQLSTCLSGFLDEVMKKYGSLVPLSEKDVLGR----LKDVFNEDFSN--RKPFINREITNYR---ARHQKCNFRIFYNKHMLDMDDLATLDGQNWLNDQVINMYGELIMDAVPDK------VHFFNSFFHRQLVTKGYNGVKRWTKK--VDLFKKSLLLIPIHLE-VHWSLITVTLSSRIISFYDSQGIHFKFCVENIRKYLLTEAREKNRPEF-LQGWQTAVTKC--IPQQKNDSDCGVFVLQYCKCLALEQPFQFSQEDMPRVRKRIYKELCECRLLD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2JZW2-1", "uniprot_id": "A0A0G2JZW2_RAT", "id": "A0A0G2JZW2-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKKQKKILWKKGIHLAFSEKWNTGFGGFKKLYFPQNLCFLKAKLGRPVVWHRQSKHFQCNKRGLHIQKTWAQDVPLCSKTKSGVATQNVSSLYAKVKRKDTKHFISSSRSLLKLQADKLLSSAKNLGREYCREKSLLKAGPGLSANTVL-----------------GKANGHKPSTDPQASDFPMKFNGESQSPSDSGKTVV-LNKHRKR-VCYGCYQGLEHHRNRRPLIPKKFQPNQYRRVKVS-LMMYEKLSMIRFRYRIFRSQHFRTKSRVCKLRKAQQSWVQKVTGDHQENFRDNNTEGGDCSPVPSLEPKDP-CRCQPYFPDMDSSAVVKGKNCHVPDGHTKESPALDKEHGLDAAFPDQQNGSTTYTWDQP-FSSPKWECTEQIHEIPLMGHPSSDNFTPGTERALMTLGQESGTSAVSDDGVKLSVSGADESVSSVDGPVSEEPAQNKN-FQMEEDGSLRQNILSLKLLDHPYC------------------------------------------------------------------------------------KSPLDAPLVCSELKVENQVAGGKSGQTASPVDDEQLSTCLSGFLDEVMKKYGSLVPLSEKDVLGR----LKDVFNEDFSN--RKPFINREITNYR---ARHQKCNFRIFYNKHMLDMDDLATLDGQNWLNDQVINMYGELIMDAVPDK------VHFFNSFFHRQLVTKGYNGVKRWTKK--VDLFKKSLLLIPIHLE-VHWSLITVTLSSRIISFYDSQGIHFKFCVENIRKYLLTEAREKNRPEF-LQGWQTAVTKC--IPQQKNDSDCGVFVLQYCKCLALEQPFQFSQEDMPRVRKRIYKELCECRLLD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NXL6-1", "uniprot_id": "SENP5_MOUSE", "id": "Q6NXL6-1", "name": "Sentrin-specific protease 5", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKKQKKILWKKGIHLAFSEKWNAGFGSFKKFYFPQNLCFLKAKLGRPVAWHRQVKHFQCN-KGLHIQKTWIQDVPFCSKTKSGLATQNVSTLYPKVKRKDSKHFISSSRSLLKLQADKLLSSAKSLDHKYCREKSLLKAAPGLSANTVL-----------------GRANGHEPTTDPQASDFPMKFSGESQSPGDSGKTVV-LNKHRKR-VCHGCYQGLEHHRNRRPLIPKQFQLNQHRRVRAS-LMMYEKLSMIRFRYRIFRSQHFRTKSRVCKLRKAQRSWVQKVTGDHQENLRDNNTEGDNCNPVPSLEPKDP-CRCQPYFPDMDSSAVGKGKNCHVPDGHTKENPVLDKEHGLDDTFPDQQNGCVAYNWDQS-SSCPKWECTEQIHEIPLMEHPSSDKFSPETERALMALGQESGTSAVSDDREKLPVSGADKSVSSVDGPVSEEPAQNEN-FQMEEDGSLKQSILSSKLLDHPYC------------------------------------------------------------------------------------KSPLDAPLLCSEPKVENQMSGGKSSQTASPVDDEQLSTCLSGFLDEVMKKYGSLVPLSEKDVLGR----LKDVFNEDFSN--RKPFINREITNYR---ARHQKCNFRIFYNKHMLDMDDLATLDGQNWLNDQVINMYGELIMDAVPDK------VHFFNSFFHRQLVTKGYNGVKRWTKK--VDLFKKSLLLIPIHLE-VHWSLITVTLSSRIISFYDSQGIHFKFCVENIRKYLLTEAREKNRPEF-LQGWQTAVTKC--IPQQKNDSDCGVFVLQYCKCLALEQPFQFSQEDMPRVRKRIYKELCECRLLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96HI0-1", "uniprot_id": "SENP5_HUMAN", "id": "Q96HI0-1", "name": "Sentrin-specific protease 5", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKKQRKILWRKGIHLAFSEKWNTGFGGFKKFYFHQHLCILKAKLGRPVTWNRQLRHFQGRKKALQIQKTWIKDEPLCAKTKFNVATQNVSTLSSKVKRKDAKHFISSSKTLLRLQAEKLLSSAKNSDHEYCREKNLLKAVTDFPSNSAL-----------------GQANGHRPRTDPQPSDFPMKFNGESQSPGESGTIVVTLNNHKRKGFCYGCCQGPEHHRNGGPLIPKKFQLNQHRRIKLSPLMMYEKLSMIRFRYRILRSQHFRTKSKVCKLRKAQRSWVQKVTGDHQETRREN-GEGGSCSPFPSPEPKDPSCRHQPYFPDMDSSAVVKGTNSHVPDCHTKGSSFLGKELSLDEAFPDQQNGSATNAWDQSSCSSPKWECTELIHDIPLPEHRSNTMFISETEREIMTLGQENQTSSVSDDRVKLSVSGADTSVSSVDGPVSQKAVQNENSYQMEEDGSLKQSILSSELLDHPYC------------------------------------------------------------------------------------KSPLEAPLVCSGLKLENQVGGGKNSQKASPVDDEQLSVCLSGFLDEVMKKYGSLVPLSEKEVLGR----LKDVFNEDFSN--RKPFINREITNYR---ARHQKCNFRIFYNKHMLDMDDLATLDGQNWLNDQVINMYGELIMDAVPDK------VHFFNSFFHRQLVTKGYNGVKRWTKK--VDLFKKSLLLIPIHLE-VHWSLITVTLSNRIISFYDSQGIHFKFCVENIRKYLLTEAREKNRPEF-LQGWQTAVTKC--IPQQKNDSDCGVFVLQYCKCLALEQPFQFSQEDMPRVRKRIYKELCECRLMD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWK5-1", "uniprot_id": "Q9VWK5_DROME", "id": "Q9VWK5-1", "name": "", "aln": "MSLPPEDTDLSTNSAYESALQIASNVSAARVVGSAVGQRFSPSPAAHPNVIERVASHVDSRRSTFPSWGNPSVAPRGSEEAAANATATQLLWAENQGLPTSHLLPTEQAFETLNTNAYCSPPGDSRFTFPSQNYSPLLPRCVPVPNQRYSPDGSPIHQLHELQNCPLIDSPIRLRFPSPLPEPPSLPTITLTVDALIDLDQNNQVAYYVQQYNNQPVLYQQNIHIGTGIQLCDQASENNQPIILHIVEHNPQTITESQEQFHQVVPEIQINNIQEQDQKFENGISEQNHPIATEAQDQTLTEIRDENQIVLAVQEKNLTRASEIQDQNQQTLTEIPEKCLQIASPVTTDIQVQSPQVVIEIQEQNHQSVTEIQEEVHQTAPEIQVNVFQTSSDIQGQNHQIVTEEQNHQTITETQEDYSAVSEIQWENLSFSAEIQEQNQQIVTEVTKLASPSVTDIQAQSPQSVIEIQDDDDEDLKFESDDLHTIPEIQEKNQQSPQFVIEIHYDNEDLKFASDNQEQDQQTAELQKERFQFASEIEKRDLQIVTDTHKQNYHNVTDIPFATYIQEENEQLTPEDQEEDQHYLNFEGNQQFQLQKQDQLSVPQIQKQTHQFESKVKKRKLQPFSEYQQKGQKDHIQERQYIQQEFTIHSNQAYSKVQYIQTIQTATPYVPQLEISQENSFEVQPAYEVNEGQRDRELVSYTGHEHQNFVDEVSTPLPPAEAQPGSTSEDISDPVSPEHWEQLESLDPSTICIRKTFNLIRDISESLVADPEQPEAEAHRKSIFLLRQKLADVCHKVLTEIIHGRATDEIISILREILEQTKEIPPRPTPKRDLQEDISMGLEILKKIRGMLSGWYSSRESETDSTDTGTGFQAQNGKGFGAGRQPENSFLSQKRRNQEENPRLIKYRRVDNSFPRLITNETAEDLIPNNSMAKRDQPQSSKRLSIFNPPVYTQHRVRNDAPHVPTPFDDEESSQRLANAGPSSRPMTYSDAVRLGHNGISESRVNGHSSHTVRREPSRLHRSILSHEMNCKDQEQYNELIRTQTNYVGSRYLKPGTPPTFQRAKAQSA------------------------------------------------------------TSSSCSLQDNQSNITDSFPSPHGRANPELTEYAKLINRQENEENRSPAPQQPKRNASNSSASHASTISSSASSSCSTCSTCSSSDTEPMLVKDSPEVKEANEANEAN-----------------------------------------------------EANEANETKENDAPQPTTTRIKKPDFLHRRFANCIFLRNDFAENFKARANRRQLESMHLLGIAEQQANESKDERLAYEKKLREVMFRSGAPHRPFFEIGPLEQPEEKKETKLIPLTKEDHARFQEMTTIEVTTNLIFKYNLQITTDDIFTFVDGEWLNDAIINFYMSMLTERSEKRAGELPATYAMNTFFMPRLLQAGYAGVRRWTRK--VDLFSKDIIPVPVHCGNVHWCMAIIHLRNKTIFYYDSMGRPNQPALDALVKYLHEESLDKRKQPFDMTGFVVENAQN--IPRQGNSSDCGVFSCMFAEYITRDVPITFSQAEMLYFRTKMALEIADGKLWQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQH8-1", "uniprot_id": "Q8IQH8_DROME", "id": "Q8IQH8-1", "name": "Ubiquitin-like protease family profile domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLAFEKEIVEKSRYFDLITKECQDYPMAKTM--PVLK--------------------------------------QPEN------------------------------FQEQEEDVV----MAVQEK------LKFFR-------KLTSNGPAVPTPLKVVEKED-------------------IGHK--------------------------------------------------------------------------------------------------------------------------------------------------------------EIPKVVKKVDR------------------------------------------------KTKLLQAIPAVFKHSHN-------------------------------------------------------------------------------------RRFRRSLFLRSNYIEQFRRWTDQKNKLNRKRLNEAHQLCLKAKHERIACEIDRYKKLILKQSVH---------VIEDIRISSELIPLTKEHHDRLMELSKYPLQQVIVAKFNLDICGSDIKILTSGGWLNDKIINFYMNLLVERSEKRPGTVPSVYAMSTFFVPRLLQSGFDGVKRWTRK--VDLFSMDLILVPVHQMLVHWCLVIIDLPAKTMLYYNSRGRGDPNLMRALVKYLQMESEDKLGLCLDTSEFRIEDAQN--VPQQDNMNDCGVFVCMFAEYLTRDAPITFSKKDMKYFRTKMVLELTGDQLWK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02724-1", "uniprot_id": "ULP1_YEAST", "id": "Q02724-1", "name": "Ubiquitin-like-specific protease 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVEVDKHRNTLQYHKKNPYSPLFSPISTYRCYPRVLNNPSESRRSASFSGIYKKRTNTSRFNYLNDRRVLSMEESMKDGSDRASKAGFIGGIRETLWNSGKYLWHTFVKNEPRNFDGSEVEASGNSDVESRSSG---------------SRSSDVPYGLRENYSSDTRKHKFDTSTWALPNKRRRIESEGVGTPSTSPISSLASQKSNCDSDNSITFSRDPFGWNKWKTS------AIGSNSENNTSDQKNSYDRRQYGTAFIRKKK------------------------------------------------------------------------------------------------------------------------VAKQNINNTKLVSRAQSEEVTYLRQIFNGEYKVPKILKEERERQLKLMDMDKEKDTGLKKSIIDLTEKIKTILIENNKN---------------------------------------------------------------------------------------RLQTRNENDDDLVFVKEKKISSLERKHKDYLNQKLKFDRSILEFEKDFKRYNEILNERKKIQ---EDLKKKKEQLAKKKLVPELNEKDDDQVQKALASRENTQLMNRDNIEITVRDFKTLAPRRWLNDTIIEFFMKYIEKSTPNT-------VAFNSFFYTNLSERGYQGVRRWMKRKKTQIDKLDKIFTPINLNQSHWALGIIDLKKKTIGYVDSLSNGPNAMSFAILTDLQKYVMEESKHTI----GEDFDLIHLDCPQQPNGYDCGIYVCMNTLYGSADAPLDFDYKDAIRMRRFIAHLILTDALK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . : *: : **** ::::: . : . . :.:** .* *: .*:** : :: . . : *:: **.: : . : : : :* : * . : * * *** : .. : : : ", "identical_positions": 22, "similar_positions": 48, "identity": "1.35%" }, { "cls_id": "homologset.agr.SGD:S000005943", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZT95-1", "uniprot_id": "D3ZT95_RAT", "id": "D3ZT95-1", "name": "DNA repair endonuclease XPF", "aln": "---------------------------------------------MERGLPGERQSMAP--------------------------------LLEYERQQVLELLDSDGLVVCARGLGADRLLYHFLRLHCHPA--------CLVLVLNTQPAEEEYFINQLKIEGVEHLPR---------------------RVTNEIASNSRYEVYTQGGIIFATSRILVVDFLTGRIPSDLITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVERVMRNLFVKKLYLWPRFHVAVNSFLEQH----KPEVVEIHVSMTPAMLAIQTAILDVLNACLKELKYHNPSLEVEDLSLENALGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESLRATEK----VFGQNSGWLFLDASTSMFVNARARVYRVPDVKLSKKTKTSEKMAGPEEQETKKELVLESNPKWEALTEVL-KEIETENKESEALGGPGQVLICASDDRTCCQLRDYLTAGAEAFLLRLYRKTFEKDGKAEEVWVNFRKGDGPKRTMKSDKRPKDAQNKERASTKRGALKRKKKRELTLTQVLGTAEEPPEEGAVEEDLHKQTGSS-------PEVCGGEI----------QHESFDLNVSSDAAYGILKEPLTIIHPLLG-CSDPYALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASR---PGKPLRVYFFVYGGSTEEQRYLTALRKEKEAFEKLIREKASMVVPEEREGRDETNLDLAR--GTAAMDTPTDTRKAGGQE--RNGTQPSIVVDMREFRSELPSLIHRRGIDIEPVTLEVGDYILTPELCVERKSVSDLIGSLHSGRLYSQCLAMSRYYRRPVLLIEFDPSKPFSLAPRGAFVQEMSSS--------------DVSSKLTLLTLHFPRLRLLWCPSPHATAELFEELKQNKPQPDAATAMAITADSE------TLPE-SDRYNPGPQDFVLKMPGVNAKNCRSLMNQVQNIAELATLSLERLTGILGHSGNAKQLHDFLHTAYADLVSKGRVRK-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZD4-1", "uniprot_id": "XPF_MOUSE", "id": "Q9QZD4-1", "name": "DNA repair endonuclease XPF", "aln": "---------------------------------------------MEPGLSGERRSMAP--------------------------------LLEYERQQVLELLDSDGLVVCARGLGTDRLLYHFLRLHCHPA--------CLVLVLNTQPAEEEYFINQLKIEGVEHLPR---------------------RVTNEIASNSRYEVYTQGGIIFATSRILVVDFLTGRIPSDLITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVERVMRNLFVRKLYLWPRFHVAVNSFLEQH----KPEVVEIHVSMTPAMLAIQTAILDILNACLKELKCHNPSLEVEDLSLENALGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESLRATEK----VFGQNSGWLFLDASTSMFVNARARVYRVPDVKLNKKAKTSEKTSSPEVQETKKELVLESNPKWEALTDVL-KEIEAENKESEALGGPGRVLICASDDRTCCQLRDYLSAGAETFLLRLYRKTFEKDGKAEEVWVNVRKGDGPKRTTKSDKRPKAAPNKERASAKRGAPLKRKKQELTLTQVLGSAEEPPEDKALEEDLCRQTSSS-------PEGCGVEI----------KRESFDLNVSSDAAYGILKEPLTIIHPLLG-CSDPYALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASR---PGKPLRVYFLIYGGSTEEQRYLTALRKEKEAFEKLIREKASMVVPEEREGRDETNLDLAR--GSAALDAPTDTRKAGGQE--QNGTQSSIVVDMREFRSELPSLIHRRGIDIEPVTLEVGDYILTPELCVERKSVSDLIGSLHSGRLYSQCLAMSRYYRRPVLLIEFDPSKPFSLAPRGAFFQEMSSS--------------DVSSKLTLLTLHFPRLRLLWCPSPHATAELFEELKQNKPQPDAATAMAITADSE------TLPE-SDRYNPGPQDFVLKMPGVNAKNCRSLMNQVKNIAELATLSLERLTTILGHSGNAKQLHDFLHTAYADLVSKGRVRK-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92889-1", "uniprot_id": "XPF_HUMAN", "id": "Q92889-1", "name": "DNA repair endonuclease XPF", "aln": "---------------------------------------------MESGQPARRIAMAP--------------------------------LLEYERQLVLELLDTDGLVVCARGLGADRLLYHFLQLHCHPA--------CLVLVLNTQPAEEEYFINQLKIEGVEHLPR---------------------RVTNEITSNSRYEVYTQGGVIFATSRILVVDFLTDRIPSDLITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVERVMRNLFVRKLYLWPRFHVAVNSFLEQH----KPEVVEIHVSMTPTMLAIQTAILDILNACLKELKCHNPSLEVEDLSLENAIGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESLRATEK----AFGQNSGWLFLDSSTSMFINARARVYHLPDAKMSKKEKISEKMEIKEGEETKKELVLESNPKWEALTEVL-KEIEAENKESEALGGPGQVLICASDDRTCSQLRDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKK-KKRKLTLTQMVGKPEELEEEGDVEEGYRREISSS-------PESCPEEI----------KHEEFDVNLSSDAAFGILKEPLTIIHPLLG-CSDPYALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASR---PGKPLRVYFLIYGGSTEEQRYLTALRKEKEAFEKLIREKASMVVPEEREGRDETNLDLVR--GTASADVSTDTRKAGGQE--QNGTQQSIVVDMREFRSELPSLIHRRGIDIEPVTLEVGDYILTPEMCVERKSISDLIGSLNNGRLYSQCISMSRYYKRPVLLIEFDPSKPFSLTSRGALFQEISSN--------------DISSKLTLLTLHFPRLRILWCPSPHATAELFEELKQSKPQPDAATALAITADSE------TLPE-SEKYNPGPQDFLLKMPGVNAKNCRSLMHHVKNIAELAALSQDELTSILGNAANAKQLYDFIHTSFAEVVSKGKGKK-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U361-1", "uniprot_id": "A0AB32U361_DANRE", "id": "A0AB32U361-1", "name": "DNA repair endonuclease XPF", "aln": "-------------------------------------------------------MASA--------------------------------LLEYETEMFLSVFSTDGLLITAEGLGIDRLLLHFMKVYSEEG--------SLVLLLNTSTPEQEYLTERLRAEGVTHLPQ---------------------TVTSDVQSADRYNVYTKGGVLFVTSRILVVDFLTDRIPAHLVTGILVYRAHNIIESCQEAFILRLYRQKNKTGFIKAFTDKATSFSSGFCKVERVMRNLFVKKLFLWPRFQASVNATLDKH----KPDVVELHVTLTPAMRAIQSSILDIMNACLKELKRYNPTLEAEDLSLENSLGTAFEKTIRHYLDPLWHQLGSRTKSLVQDLKILRTLLLYLTQYDCVTFLNLLESLRTSQK----SFGSNSGWLFLDSSMSMFVNARSRVYRIQESK--KKLKVGETEQKQNLAPPKRELVLEKNPKWEALTEVL-QEIEKENSKSEHE--PGRVLICASDDRTCAQLKEYIQKGPEHLLNRLYSRTIGKE-DPQPDLLKLDKGWQKKDSARS-KGKNSRQKRTKANSKK-------------PAKMEKLSRVSQDDSADKDLN-ENSED-------EGGLIEEE----------EEEEIVLDLSSDDYYGILKEPLTVIHPLKG-CSDPYSLTRVLHEVDPMFVVLYDAELSFVRQLEIYKACR---PGKPLRVYFLIYGGSTEEQRYLTALNKEKQAFEHLIREKASMVVPEEREGREDTNLDLVR--SQEPASAATNTRKAGGLE--EVKEPHRIIVDMREFRSELPSLLHRRGLDIEPVTLEVGDYILTSDICVERKSVSDLIGSLQSGRLYTQCLSMTRFYRRPVLLIEFDPAKPFSLVARSDFRQEISAN--------------DVTSKLTLLTLHFPRLRLLWCPSPYVTAELFQELKHGRTEPDASTAQAVTAESE------TVTESADLYNPGPYDFLLRMPGVNVKNVKSLIKHVSCLADLVTFSQETLSEILGSSSNARMLYEFIHNP-MDVRPIQKNK------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24087-1", "uniprot_id": "XPF_DROME", "id": "Q24087-1", "name": "DNA repair endonuclease XPF", "aln": "---------------------------------MADSCAENAAKGTENERPKEVEASADTVPQVEEGVEEYLKRKNMV-------------LLDYEKQMFLDLVEADGLLVCAKGLSYDRVVISILKAYSDSG--------NLVLVINSSDWEEQYYKSKIEPKYVHEVAS---------------------TAT------ERERVYLEGGLQFISTRILVVDLLKQRIPIELISGIIVLRAHTIIESCQEAFALRLFRQKNKTGFVKAFSSSPEAFTIGYSHVERTMRNLFVKHLYIWPRFHESVRTVLQPW----KIQSIEMHVPISQNITSIQSHILEIMNFLVQEIKRINRTVDMEAVTVENCVTKSFHKILQAQLDCIWHQLNSQTKLIVADLKILRSLMISTMYHDAVSAYAFMKRYRSTEY----ALS-NSGWTLLDAAEQIFKLSRQRVFNG-----------------------QQEFEPEPCPKWQTLTDLLTKEIPGDMRRSRRSEQQPKVLILCQDARTCHQLKQYLTQGGPRFLL---QQALQHEVPVGKLSDNYAKESQTRSAPPKNVSSNKELRREEVSGSQPPLAGMDELAQLLSESETEGQHFEESYMLTMTQPVEVGPAAIDIKPDPDVSIFET----------IPELEQFDVTAALAS-VPHQPYICLQTFKTEREGSMALEHMLEQLQPHYVVMYNMNVTAIRQLEVFEARRRLPPADRMKVYFLIHARTVEEQAYLTSLRREKAAFEFIIDTKSKMVIPKYQDGKTDEAFLLLKTYDDEPTDENAKSRQAGGQAPQATKETPKVIVDMREFRSDLPCLIHKRGLEVLPLTITIGDYILTPDICVERKSISDLIGSLNSGRLYNQCVQMQRHYAKPILLIEFDQNKPFHLQGKFMLSQQTSMAN------------ADIVQKLQLLTLHFPKLRLIWSPSPYATAQLFEELKLGKPEPDPQTAAALGSDEP------TAGE-QLHFNSGIYDFLLRLPGVHTRNIHGLLRKGGSLRQLLLRSQKELEELLQSQESAKLLYDILHVAHLPEKDEVTGSTALLAASKQFGAGSHNRFRMAAAASRRGRR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06777-1", "uniprot_id": "RAD1_YEAST", "id": "P06777-1", "name": "DNA repair protein RAD1", "aln": "MSQLFYQGDSDDELQEELTRQTTQASQSSKIKNEDEPDDSNHLNEVENEDSKVLDDDAVLYPLIPNEPDDIETSKPNINDIRPVDIQLTLPLPFQQKVVENSLITEDALIIMGKGLGLLDIVANLLHVLATPTSINGQLKRALVLVLNAKPIDNVRIKEALEELSWFSNTGKDDDDTAVESDDELFERPFNVVTADSLSIEKRRKLYISGGILSITSRILIVDLLSGIVHPNRVTGMLVLNADSLRHNSNESFILEIYRSKNTWGFIKAFSEAPETFVMEFSPLRTKMKELRLKNVLLWPRFRVEVSSCLNATNKTSHNKVIEVKVSLTNSMSQIQFGLMECLKKCIAELSRKNPELALDWWNMENVLDINFIRSIDSVMVPNWHRISYESKQLVKDIRFLRHLLKMLVTSDAVDFFGEIQLSLDANKPSVSRKYSESPWLLVDEAQLVISYAKKRIFYKNEYTLEENPKWEQLIHILHDISHERMTNHLQGPTLVACSDNLTCLELAKVLNASNKKRGVRQVLLNKLKWYRKQREETKKLVKEVQSQDTFPENATLNVSSTFSKEQVTTKRRRTRGASQVAAVEKLRNAGTNVDMEVVFEDHKLSEEIKKGSGDDLDDGQEENAANDSKIFEIQEQENEILIDDGDAEFDNGELEYVGDLPQHITTHFNKDLWAEHCNEYEYVDRQDEILISTFKSLNDNCSLQEMMPSYIIMFEPDISFIRQIEVYKAIVK---DLQPKVYFMYYGESIEEQSHLTAIKREKDAFTKLIRENANLSHHFETNEDLSHYKNLAERKLKLSKLRKSNTRNAGGQQGFHNLTQDVVIVDTREFNASLPGLLYRYGIRVIPCMLTVGDYVITPDICLERKSISDLIGSLQNNRLANQCKKMLKYYAYPTLLIEFDEGQSFSLEPFSERRNYKNKDISTVHPISSKLSQDEIQLKLAKLVLRFPTLKIIWSSSPLQTVNIILELKLGREQPDPSNAVILGTNKVRSDFNSTAKGLKDGDNESKFKRLLNVPGVSKIDYFNLRKKIKSFNKLQKLSWNEINELINDEDLTDRIYYFLRTEKEEQEQESTDENLESPGKTTDDNALHDHHNDVPEAPV----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : .:. *.*:: ..**. :: ::: . ***::*:. :: . :. . .: .* .:* .**: ::***:**:*. : . ::*::* .*. : ...:*:* *.::*.**. **:***:. . :* :. :. *::* :::: :****: * : *: : . :*::*.:: : ** ::: :: : *:. * : : .:** : * : : : **::. .:* :* *:::** *: *.* :: :: :* * ::* : :: :: *:: :: *. : :: * . .: : :: . * .: . : : . . : . . . :. : : .: : . : . *.:: * :::::: ::: :**:*::.* :***: :. : *** :**::.:** ** :* ::.: : . * . . :.:*:*** ::** ***.:.** *::: *: : * : :***::*.::*:****:*******:..** .** * :.* * ****** :.* * : . :: ** *.*:** *:::*..** *.::: *** .: :**. .* : ::. * * . . :*.:*** : .* .: : .* * . : :: : :: ::: ", "identical_positions": 159, "similar_positions": 273, "identity": "14.36%" }, { "cls_id": "homologset.agr.SGD:S000005944", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A4C5-1", "uniprot_id": "A0A8I6A4C5_RAT", "id": "A0A8I6A4C5-1", "name": "Methylenetetrahydrofolate reductase", "aln": "MNHQKAGVLPDGHCYTSLGMWASEAGCVGLSVPPSIRNPAMSNEARRSGSPSPRSEGSSS-GSESSKDSSRCSTPSLDPDRHERLREKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTALNYCGLETILHMTCCQQRQEEISGHLHRAKQLGLKNIMALRGDP-VGDHWEA---EEGGFSYATDLVKHIRNEFGDYFDICVAGYPKGHPDAESFED------DLKHLKEKVSAGADFIITQLFFEASSFFSFVKACED-IGISCPILPGIFPIQGYTSLRQLVKLSKLEVPQTIKDVIEP--------IKDNDAAIRNYGIELAVNLCRELLD--SGLVPGLHFYTLNREVATMEVLKQLGMWTEDPRRPLP--------------------------------WAVSAHPKRREED------------------------------VRPIFWASRPKSYIYRTQGWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWNDEPLAAETSLMKEELLRVNRLGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELR--VNYHIVDVKGENITNAPELQPNAVTWGIFPGREIVQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFLLDNCLWQVVEDTFELLNRHTT-KKEAQAP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WU20-1", "uniprot_id": "MTHR_MOUSE", "id": "Q9WU20-1", "name": "Methylenetetrahydrofolate reductase (NADPH)", "aln": "----------------------------------------MVNEARGSGSPNPRSEGSSS-GSESSKDSSRCSTPSLDPERHERLREKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDP-VGDHWEA---EEGGFSYATDLVKHIRTEFADYFDICVAGYPRGHPDAESFED------DLKHLKEKVSAGADFIITQLFFEASTFFSFVKACTE-IGISCPILPGIFPIQGYTSLRQLVKLSKLEVPQKIKDVIEP--------IKDNDAAIRNYGIELAVSLCRELLD--SGLVPGLHFYTLNREVATMEVLKQLGMWTEDPRRPLP--------------------------------WALSAHPKRREED------------------------------VRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWNDEPLAAETSLMKEELLRVNRLGILTINSQPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELR--VNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDSCLWQVVEDTFELLNRHPT-ERETQAP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42898-1", "uniprot_id": "MTHR_HUMAN", "id": "P42898-1", "name": "Methylenetetrahydrofolate reductase (NADPH)", "aln": "----------------------------------------MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDP-IGDQWEE---EEGGFNYAVDLVKHIRSEFGDYFDICVAGYPKGHPEAGSFEA------DLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTD-MGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEP--------IKDNDAAIRNYGIELAVSLCQELLA--SGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLP--------------------------------WALSAHPKRREED------------------------------VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELR--VNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYEEESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLNRPTQNARETEAP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0V153-1", "uniprot_id": "B0V153_DANRE", "id": "B0V153-1", "name": "Methylenetetrahydrofolate reductase (NADPH)", "aln": "----------------------------------------MVNQRADVGWHSKSDSSGASNSGESSRESSRCSTPVPDADRTDRLRDKMKRRIESGDHWFSLEFFPPRTSSGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESVLHLTCCNQTKEKITDHLNKAKRLGLKNIMALRGDP-VGEDWVE---EDGGFNFATDLVKHIRHEFDDYFDICVAGYPTGHPEAESYED------DLRHLKEKVDAGAHFIVTQLFFRAETFLKFVKDCRA-IGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIKQVIEP--------IKDNDAAIRNYGIQQAVEMCKVLLA--SGEVSGLHFYTLNREVATMEVLRQLGLWAEDPRRPLP--------------------------------WAISAHPKRKVED------------------------------VRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQMWGEELMSEESVYEVFTNYITGQTNRSGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGVLTINSQPNINGKASSDAIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPR--VNYQIVNVQGRNITNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDNCLWQVIEDMFALLDSSQVPQQEANEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P46151-1", "uniprot_id": "MTHR1_YEAST", "id": "P46151-1", "name": "Methylenetetrahydrofolate reductase 1", "aln": "----------------------------------------------------------------------------------MSIRDLYHARASP---FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGG----TTAEKTLTLASLAQQTLNIPVCMHLTCTNTEKAIIDDALDRCYNAGIRNILALRGDPPIGEDWLDSQSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGHCEGEAEGHEQDPLKDLVYLKEKVEAGADFVITQLFYDVEKFLTFEMLFRERISQDLPLFPGLMPINSYLLFHRAAKLSHASIPPAILSRFPPE-------IQSDDNAVKSIGVDILIELIQEIYQRTSGRIKGFHFYTLNLEKAIAQIVSQSPVLSHIVNESSEEEGEDETSGEIGSIENVPIEDADGDIVLDDSNEETVANRKRRRHSSLDSAKLIFNRAIVTEKGLRYNNENGSMPSKKALISISKGHGTLGRDATWDEFPNGRFGDSRSPAYGEIDGYGPSIKVSKS---KALELWGIPKTIG-DLKDIFIKYLEG-------STDAIPWSDLGLSAETALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWSE-WAKLFPRNTPANILLRLVHKDYCLVSIVHHDFKETDELWEMLLDQA----------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VTI0-1", "uniprot_id": "Q9VTI0_DROME", "id": "Q9VTI0-1", "name": "Methylenetetrahydrofolate reductase-like catalytic domain-containing protein", "aln": "-----------------------------------------------MHAIQVPAGGSSPGAASYIPCVTFAPDQNESVVTKQRIGTLVAERTAQHRLFYGIEVMASDPSG--RPTCLDFNHFLPLLPTFVSFVWLSQRYWDVEPVGQVESLQMAQHLATRIPVLPHVSAYRMSRQ----RLDQFLALNFSSLLAVRGDR---------VHEDQDFSISYPMVEQSIRQRGETISVCVGGYPEGYTSLGDIPQ--NSAKNMEFLKAKIDAGADCIITQLCYRPEVIVQFVKDCRA-AGISVPIVVGLMSHESFRSYSMIEQITGVHLPDDLREQLDQLHSAHMKDMKSDQDLIRRFFVSLTVRTIRNVLD-ADVGVWGFHFFTLNRFKSVQAVLQELRDLDLLKDSEKD---------------------------------------KKGYEK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : .:*.:.. . :.:: . * :: ..* . . : : *::. . *.: .: .::*:*** :: *. : :*. . : : : *..** *: . :: .** *:.***. ::*** : . :. * . *:. *::. :.: ::: :* : . : ::.:: :: :. : : : . : *:**:*** : :: . *: .. ", "identical_positions": 36, "similar_positions": 99, "identity": "4.61%" }, { "cls_id": "homologset.agr.SGD:S000005949", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8QZT1-1", "uniprot_id": "THIL_MOUSE", "id": "Q8QZT1-1", "name": "Acetyl-CoA acetyltransferase, mitochondrial", "aln": "MAALVALHG---VVRRPLLRGLLQEVRCLERSYASKPTLNEVVIVSAIRTPIGSFLGSLASQPATKLGTAAIQGAIEKAGIPKE--EVKEVYMGNVIQGGEGQAPTRQATLGAGLPISTPCTTVNKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVM--SRGATPYGGVKLEDLIVKDGLTDVYNKIHMGNCAENTAKKMNISRQEQDTYALSSYTRSKEAWDAGKFASEITPITIS-VKGKPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTITAANASTLNDGAAALVLMTAEAAQRLNVKPLARIAAFADAAVDPIDFPLAPAYAVPKVLKYAGLKKED-IAMWEVNEAFSVVVLANIKMLEIDPQKVNIHGGAVSLGHPIGMSGARIVVHMAHALKP--GEFGLASICNGGGGASALLIEKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17764-1", "uniprot_id": "THIL_RAT", "id": "P17764-1", "name": "Acetyl-CoA acetyltransferase, mitochondrial", "aln": "MAALAVLHG---VVRRPLLRGLLQEVRCLGRSYASKPTLNDVVIVSATRTPIGSFLGSLASQPATKLGTIAIQGAIEKAGIPKE--EVKEVYMGNVIQGGEGQAPTRQATLGAGLPIATPCTTVNKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVM--SRGATPYGGVKLEDLIVKDGLTDVYNKIHMGNCAENTAKKLSISREEQDKYAIGSYTRSKEAWDAGKFANEITPITIS-VKGKPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAAVVLMTAEAAQRLKVKPLARIAAFADAAVDPIDFPLAPAYAVPKVLKYAGLKKED-IAMWEVNEAFSVVVLANIKMLEIDPQKVNVHGGAVSLGHPIGMSGARIVVHLAHALKQ--GEFGLASICNGGGGASAVLIEKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24752-1", "uniprot_id": "THIL_HUMAN", "id": "P24752-1", "name": "Acetyl-CoA acetyltransferase, mitochondrial", "aln": "MAVLAALLRSGARSRSPLLRRLVQEIRYVERSYVSKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKE--EVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVM--NRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTVT-VKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKED-IAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQ--GEYGLASICNGGGGASAMLIQKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6AZA0-1", "uniprot_id": "THIL_DANRE", "id": "Q6AZA0-1", "name": "Acetyl-CoA acetyltransferase, mitochondrial", "aln": "-MTSRALYS----TRSQLCRHLAH--KYLSRSYSTRPSLNEVVIVSAVRTPIGSFKGSLSTLPATKLGSIAIKGAIDKAGIPVE--EVKEVYMGNVLQAGEGQAPTRQALLGAGLPLSTPATTINKVCASGMKSIMLASQSLMCGHQDVMVAGGMESMSQVPYIM--AREAPPYGGVKMEDLIVKDGLTDVYNKFHMGNCAENTAKNSSISREEQDAFAIKSYTLSKAAWESGILAKEVVPVSIP-QRGKPDVVVKEDEEYRKVDFSKVPKLKAVFLKENGTVTAANASTLNDGAAALVLMTADAAQRLNVTPLAKIVAFADAAVAPIDFPIAPAFAVPKVLKAAGIKKED-IAMWEINEAFSVVVLANIKMLDIDPDRVNINGGAVSLGHPIGMSGARIVGHMVHNLKS--GQYGLAGICNGGGGASSIVIQKF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3N9-1", "uniprot_id": "Q9W3N9_DROME", "id": "Q9W3N9-1", "name": "", "aln": "-----------------MSARLLQATRRWSAHRNYSSKIAEVVVVSAARTPIGSFQSQLAPLTATQLGARAIEAAIEKAGIAKT--DVQEVIMGNVVSAGLGQAPARQAAIFAGLPTNVCCTTVNKVCSSGMKAVMLGAQSLMLGYADVVVAGGMESMSNVPYYL--KRGATPYGGVNLTDGIVFDGLWDVYNKFHMGNCAENTAKKLEITRQQQDDFAIESYKRSAAAWANKVFQDEIAPVKIQ-QKRKPEIVISEDEEYKRVNFDKFGQLATVFQRENGTVTAGNASTLNDGGAAVVLMSAEAAQKAGIKPLARIVAFQDAETDPIDFPIAPALAIPKLLKRAGVRKED-VAMWEVNEAFSLVVLANIKKLDVDPAKVNVHGGAVSIGHPIGMSGARLVAHLSHSLKK--GELGCASICNGGGGASSILIEKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41338-1", "uniprot_id": "ERG10_YEAST", "id": "P41338-1", "name": "Acetyl-CoA acetyltransferase", "aln": "-------------------------------------MSQNVYIVSTARTPIGSFQGSLSSKTAVELGAVALKGALAKVPELDASKDFDEIIFGNVLSANLGQAPARQVALAAGLSNHIVASTVNKVCASAMKAIILGAQSIKCGNADVVVAGGCESMTNAPYYMPAARAGAKFGQTVLVDGVERDGLNDAYDGLAMGVHAEKCARDWDITREQQDNFAIESYQKSQKSQKEGKFDNEIVPVTIKGFRGKPDTQVTKDEEPARLHVEKLRSARTVFQKENGTVTAANASPINDGAAAVILVSEKVLKEKNLKPLAIIKGWGEAAHQPADFTWAPSLAVPKALKHAGIEDINSVDYFEFNEAFSVVGLVNTKILKLDPSKVNVYGGAVALGHPLGCSGARVVVTLLSILQQEGGKIGVAAICNGGGGASSIVIEKI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :**: ******* ..*: .*.:**: *::.*: *. :..* :***:... ****:**. : ***. .:*:****:*.**::::.:**: * **:**** ***::.** : * .. :* . : * : *** *.*: : ** **: *:. .*:*::** :*: ** * : : .*: *:.: : :*: :.:*** ::...*. . :** :****:**.***.:***.**::*:: .. :. :.*** * .: :* * **. ** * . ** .*:.. : : :*.*****:* *.* * *.:** :**: ****::***:* ****:* : *: *: * *.*********:::*:*:", "identical_positions": 154, "similar_positions": 131, "identity": "35.4%" }, { "cls_id": "homologset.agr.SGD:S000005950", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5EBA1-1", "uniprot_id": "SUV3_RAT", "id": "Q5EBA1-1", "name": "ATP-dependent RNA helicase SUPV3L1, mitochondrial", "aln": "---------MSLPRCALLWARLPAGRGAGPRAAPCSALRALVGSFPGASGRVPCLA-ASSSASGGSKAPNTSLFVPLTVKPQGPSADGDVGAELTRPLDKNEVKKILDKFYKRQEIQKLSADYGLDARLFHQAFISFRNYIMQSHSLDVDIHIVLNDICFSAAHVDDLFPFFLR--------------------HAKQIFPVLECKDDLRQIS--DLRRPPNWYPEARAIQRKIIFHSGPTNSGKTYHAIQRYLSATSGVYCGPLKLLAHEIFEKSNAAGVPCDLVTGEERL-TVEPEGKQATHVSCTVEMCNVATPYEVAVIDEIQMIRDPARGWAWTRALLGLCAEEVHLCGESAAIDLVTELLYTTGEEVEVQKYERLTPISVLDRALES-LDNLRPGDCIVCFSKNDIYSVSRQIEIRG-LESAVIYGSLPPGTKLAQARKFNDPNDPCKILVATDAIGMGLNLSIRRIIFYSLIKPSINEKGEKELEPITTSQALQIAGRAGRFSSHFKEG-----EVTTMHRDDLALLKEILNRPVDPIQAAGLHPTAEQIEMFAYHLPE--TTLSNLIDIFVDFAQVDG-QYFVCNMDDFKFSAELIQHIPLSLRVRYVFCTAPINKKQPFVCSSLLQFARQYSRNEPLTFAWLRRYIKWPLL--PPKNIKDLMDLEAVHDVFDLYLWLSYRFIDMFPDSSFVRSLQKELDVIIQEGVHNITKLIKISESHKLLNLE--PSGSQSRLPGASKSPARRTRGTKTG-NKAAEPPSPSDKELPLASRLVQQGLLTADMLKQLQKEWLTQRP-------EQGKEK----------VGTRRKKKDPNSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80YD1-1", "uniprot_id": "SUV3_MOUSE", "id": "Q80YD1-1", "name": "ATP-dependent RNA helicase SUPV3L1, mitochondrial", "aln": "---------MSLPRCTLLWARLPAGRGAGPRAAPCSALRALVGSFPGASGRVPCLA-ASSSASGGSKAPNTSLFVPLTVKPQGPSADGDVGAELTRPLDKNEVKKILDKFYKRQEIQKLSADYGLDARLFHQAFISFRNYIMQSHSLDVDIHIVLNDICFSAAHVDDLFPFFLR--------------------HAKQIFPVLECKDDLRKIS--DLRIPPNWYPEARARQRKIIFHSGPTNSGKTYHAIQRYLSATSGVYCGPLKLLAHEIFEKSNAAGVPCDLVTGEERL-TVEPEGKQATHVSCTVEMCNVATPYEVAVIDEIQMIRDPARGWAWTRALLGLCAEEVHLCGESAAINLVSELLYTTGEEVEVQKYERLTPISVLDHALES-LDNLQPGDCIVCFSKNDIYSVSRQIEIRG-LESAVIYGSLPPGTKLAQARKFNDPNDPCKILVATDAIGMGLNLSIRRIIFYSLIKPSINEKGEKELEPITTSQALQIAGRAGRFSSHFKEG-----QVTTMHRDDLALLKDILNRPVDPIQAAGLHPTAEQIEMFAYHLPE--TTLSNLIDIFVDFAQVDG-QYFVCNMDDFKFSAELIQHIPLSLRVRYVFCTAPINKKQPFVCSSLLQFARQYSRNEPLTFAWLRRYIKWPLL--PPKNIKDLMDLEAVHDVFDLYLWLSYRFIDMFPDSSLVRSLQKELDAIIQEGVHNITKLIKISESRKLLNLESLPSGDQSRLSGASKSPARRTRGTKSAGNKATEPLSPSDKELPLASRLVQQGLLTADMLRQLQKEWLTQQP-------EHSREK----------VGTRRKKKDPDSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IYB8-1", "uniprot_id": "SUV3_HUMAN", "id": "Q8IYB8-1", "name": "ATP-dependent RNA helicase SUPV3L1, mitochondrial", "aln": "---------MSFSR-ALLWARLPAGRQAGHRAAICSALRPHFGPFPGVLGQVSVLATASSSASGGSKIPNTSLFVPLTVKPQGPSADGDVGAELTRPLDKNEVKKVLDKFYKRKEIQKLGADYGLDARLFHQAFISFRNYIMQSHSLDVDIHIVLNDICFGAAHADDLFPFFLR--------------------HAKQIFPVLDCKDDLRKIS--DLRIPPNWYPDARAMQRKIIFHSGPTNSGKTYHAIQKYFSAKSGVYCGPLKLLAHEIFEKSNAAGVPCDLVTGEERV-TVQPNGKQASHVSCTVEMCSVTTPYEVAVIDEIQMIRDPARGWAWTRALLGLCAEEVHLCGEPAAIDLVMELMYTTGEEVEVRDYKRLTPISVLDHALES-LDNLRPGDCIVCFSKNDIYSVSRQIEIRG-LESAVIYGSLPPGTKLAQAKKFNDPNDPCKILVATDAIGMGLNLSIRRIIFYSLIKPSINEKGERELEPITTSQALQIAGRAGRFSSRFKEG-----EVTTMNHEDLSLLKEILKRPVDPIRAAGLHPTAEQIEMFAYHLPD--ATLSNLIDIFVDFSQVDG-QYFVCNMDDFKFSAELIQHIPLSLRVRYVFCTAPINKKQPFVCSSLLQFARQYSRNEPLTFAWLRRYIKWPLL--PPKNIKDLMDLEAVHDVLDLYLWLSYRFMDMFPDASLIRDLQKELDGIIQDGVHNITKLIKMSETHKLLNLEGFPSGSQSRLSGTLKSQARRTRGTKALGSKATEPPSPDAGELSLASRLVQQGLLTPDMLKQLEKEWMTQQT-------EHNKEKTESGTHP---KGTRRKKKEPDSD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4IG62-1", "uniprot_id": "SUV3_DANRE", "id": "A4IG62-1", "name": "ATP-dependent RNA helicase SUPV3L1, mitochondrial", "aln": "---------MSVNRCIYLLSRSHIRYRVCASTN-LSTVSTLSTTQHSTRRTFDKLS-TRHSSSGSSRPLDTSLFIPLPVKTD-EDAEGSVGAELTKPLDKNELLKVLNRFYKRKEMQKLASDQGLDARLFHQAFVSFRKYVLEMNSLNADLHIILNDICCGAGHIDDIFPYFMR--------------------HAKQIFPMLDCIDDLRKIS--DLRVPANWYPEARAIQRKIVFHAGPTNSGKTYHAIKRYLEAKSGVYCGPLKLLAHEIYEKSNAAGVPCDLVTGEERI-FVDPEGKPSGHIASTIEMCSVTTPYEVAVIDEIQMIKDPARGWAWTRALLGLCAEEIHVCGEAAAVDFITELMFTTGEEVEVHNYKRLTPFSISNHAVES-LDNLKPGDCIVCFSKNDIYSISRQIEIRG-LECAVIYGSLPPGTKLAQAKKFNDPDDPCKILVATDAIGMGLNLSIRRIIFNSLVKHSLNEKGEKEVDTISTSQALQIAGRAGRFSSVFKEG-----EVTTMHRDDLPVLKEILGKPVDPIATAGLHPTAEQIEMFAYHLPQ--ATLSNLIDIFVSLSQVDG-LYFVCNIDDFKFLADMIQHIPLNLRSRYVFCTAPINKKQPFVCTSFLKFARQFSRDEPLTFNWVCRQVNWPLS--PPKNIKDLVHLEAVHDVLDLYLWLSYRFMDMFPDSNQIREIQKELDENIQIGVRNITRLIRAIDSQ--------PTDTESNSSSTVPESETSQRKGRVLRSQNQRKELP--RKSSLSSRLLRDGLLTKELLSQLQKEWAREQN-------EDNSIP----------VNNGKRKKK----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN03-1", "uniprot_id": "SUV3_DROME", "id": "Q9VN03-1", "name": "ATP-dependent RNA helicase SUV3 homolog, mitochondrial", "aln": "--------MQNCRRCISLTGLLRMTLYLRPSFSIDLSLRRLHRAAFLFSRKKPETN-------------LSTLFKPVQVHAYVDSED--VGSELSGKLEKAELLKILNKFTQRREIKSLCNENGLDDYLQQQAFGSFRRFCIEAENLPVDLHITFSDITQGAGHIDDIFPYFLR--------------------HAKTVFPHLDCMDDLKKIS--DLRQPANWYSNARAITRKIVFHAGPTNSGKTYHAMERYLSAKTGVYCGPLKLLATEVYNKANERGTPCDLVTGEERK-FGISESLPANHVACTVEMTSVNTPYEVAVIDEIQQIRDPQRGWAWTRAFLGLIADEVHVCGEPGALDLLQKICETTGETVEVRLYDRLTELTVENTALGS-LDNIVPGDCIVCFSKHDIYTVSREIEARG-KEVAVIYGGLPPGTKLAQAAKFNDPANSCKVMVATDAIGMGLNLSIRRIIFYSLIKPSMNERGEREIDTISVSSALQIAGRAGRFRTQWEHG-----YVTAFKSEDLQTLQRILARTPEPIKQAGLHPTADQIELYAYHLPS--SSLSNLMDIFVNLCTVDDSLYFMCNIEDFKFLAEMIQHVALPLRARYVFCCAPINRKMPFVCSMFLKVARQYSRNEPITFDFIKKNCGWPFK--LPKTILDLVHLEAVFDVMDLYLWLSYRFMDLFPEAAYVRDAQKELDEIIQQGVFQITRLLKN---------------TEASQDGETSNYAIRR------ITHVKEPRLPSLSRGRLTERLLAQGLLTPGMLSELRKEWDAQQLGKSNSQSNENSEPVVNSDDEDNYSGIGRKTRKKRRK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32580-1", "uniprot_id": "SUV3_YEAST", "id": "P32580-1", "name": "ATP-dependent RNA helicase SUV3, mitochondrial", "aln": "MALVKYSTVFFPLRSLRLFVSIKKAYYHSEPHSIDLFHDKDWIVKRPKFLNLPKNEHSKLDIFQFNFNKSESNNVYLQDSSFKDNLDKAMQFIYNDKLSSLDAKQVPIKNLAWLKLRDYIYQQLKDPKLQAKTYVPSVSEIIHPSSPGNLISLLINCNKISNLVWKSVLKYSLSNNITTLDKFIHVLQQTFDHVYEQEILPMMTNTDDTDGAHNVDITNPAEWFPEARKIRRHIIMHIGPTNSGKTYRALQKLKSVDRGYYAGPLRLLAREVYDRFHAEKIRCNLLTGEEVIRDLDDRGNSAGLTSGTVEMVPINQKFDVVVLDEIQMMSDGDRGWAWTNALLGVVSKEVHLCGEKSVLPLVKSIVKMTGDKLTINEYERLGKLSVEEKPIKDGIKGLRKGDCVVAFSKKKILDLKLKIEKDTNLKVAVIYGSLPPETRVQQAALFN--NGEYDIMVASDAIGMGLNLSIDRVVFTTNMKYNG-----EELMEMTSSQIKQIGGRAGRFKSRSASGGVPQGFITSFESKVLKSVRKAIEAPVEYLKTAVTWPTDEICAQLMTQFPPGTPTSVLLQTISDELEKSSDNLFTLSDLKSKLKVIGLFEHMEDIPFFDKLKLSNAPVKDMPMVTKAFTKFCETIAKRHTRGLLSYRLPFNLLDYNCIPNESYSLEVYESLYNIITLYFWLSNRYPNYFIDMESAKDLKYFCEMIIFEKLDRLKK-----------------------------------------NPYAHKPFGSTRGHLSSSRRRLRT--------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : : . . : : . *.. : :: : :::. : * * ::: . :. . : : :. . ..:: : : : : ::* : ** *: *.:*:.:** *:*::* *********:*::: .. * *.***:*** *:::: : *:*:**** .. : : *:** : ::*.*:**** : * ******.*:**: :.*:*:*** ..: :: .: **: : :. *.** ::: : .: . :..: ***:*.***:.* :. :** : *****.*** *:: ** ** . .::**:*********** *::* : :* . .*: :: *. **.****** : * :*::. . * :: : . : : * ** : ::* .: * * .: .. : :.::.. :::*: : . :. *:* . : :... :: .. : *: .* *::.::: **:*** *: : * : :. : : * : .:.: . . . : * : ", "identical_positions": 143, "similar_positions": 207, "identity": "17.0%" }, { "cls_id": "homologset.agr.SGD:S000005951", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZS79-1", "uniprot_id": "D3ZS79_RAT", "id": "D3ZS79-1", "name": "tRNA (uracil-O(2)-)-methyltransferase", "aln": "MLFRVASSQCAESADMEELRRVPLDDPDSLLPGGFWAAVTVWLERPQVANKRLCGARIEARGRTLRPSAQA------------ECGPRQGQG-----------HGLE---------------------REPGQGS---------RADREGTAPAADLDLLWNRVSQSLVHSNPEILTFYG-PSLGSPPEAAQELDLVLRTVIPKASPHFPFTEPKKELVVQDVSSGSVTFLPLEEDNEENLEVKMSNVYQLRLHHSEGEWFISVLIFCPERWHSDGVVYPKPTWLAEELLSKLARWAVENRKSEFKSTLSLVSVLRYGRMYQELKEKYR----DMVKVWPEVTDPEKFVYEDVAIATYLLILWEEERAEKGITTKQSFVDLGCGNGLLVHILSNEGHPGRGIDVRRRKIWDMYGPQTQ---LEEGSITPSDKTLFPGVDWLIGNHSDELTPWIPVIAARSSYTCRFFVLPCCFFDFVG-RYRRRQSKKTQYREYLDFVLEVGLSCGFHVQEDCLRIPSTKRVCLIGKSRTYLPSAEVWMDEQRTRYLHSRQGLPQSLPGGGHAPSVPQIAAHDDDAGHQDSHRTFDAGAECMPEGLAAERGTGAPATGLWVPGFCPREKAERVRNCAALPRDFIDQVVLQVANLLLDGKRFNTGNSEAGSLKTWNGGGSLSLAEVAAELNSETLQQLKRECGGLQTLLRNSHQVFEVLNGRVHIRDWRRE-LQREKPPEGKRSLSAEVFKTRICWFFTHHPDGCVLPAACCPFAHGLEELRPSQTLKKQRQAP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D2Q2-1", "uniprot_id": "TRM44_MOUSE", "id": "Q9D2Q2-1", "name": "Probable tRNA (uracil-O(2)-)-methyltransferase", "aln": "---------------MEELGRVRLSDPDALLPAGFWAAVTVWLERPQVANKRLCGARMEARGRTLRSHAQA------------ECGPRQGQG-----------HGLE---------------------REPGQASPKGEPESGPRASREGTAPAADLNSLWDRVSQSLVHANPEMLAFLCGPSLGPQPEAAQELDLILRTVIPKASPHSPLTEPKKELVVQDVSSGSVTFLPLEEDNEGNLEVKTSNVYQLHLHHNEGEWFISVLIFCPERWHSDGVVYPKPAWLGEELLSKLARWAVENRKSEFKSTLSLVSILRYSRMYQELKEKYR----DMVKVWPEVTDPEKFVYEDVAIATYLLILWEEERAEKGVTTKQSFVDLGCGNGLLVHILSNEGHPGRGIDIRRRKIWDMYGPQTQ---LEEGSITPSDETLFPGVDWLIGNHSDELTPWIPVIAARSSYTCRFFVLPCCFFDFVG-RYQRQQSRKTQYREYLDFVLEVGLSCGFHVQEDCLRIPSTKRVCLIGKSRTYPPSAEVWMDEQRTRYLHSRQGHPQSRPGGAHAPSAPQTAAHD--AGLQDSCRTVNAGSECVLEGLAAERGAGAPAPGLWVPGFCPREKAERVRNCAALPRDFVDQVVLQVANLLLDRKKFNTGNSEARSLKPWNGGGSLSLAEVAAELNSETLQRLKRECGGLQTLLKNSHQVFEVLNGRVHIRDWRQE-LQRGKPPEAKQNLSAAVFKTRICWFFAHHPDGCVLPAAQCPFAHGPEELRLSQTLKKQRQAP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IYL2-1", "uniprot_id": "TRM44_HUMAN", "id": "Q8IYL2-1", "name": "Probable tRNA (uracil-O(2)-)-methyltransferase", "aln": "---------------MAEVGRTGISYPGALLPQGFWAAVEVWLERPQVANKRLCGARLEARWSAALPCAEARGPGTSAGSEQKERGPGPGQGSPGGGPGPRSLSGPEQGTACCELEEAQGQCQQEEAQREAASVPLRDSGHPGHAEGREGDFPAADLDSLWEDFSQSLARGNSELLAFLTSSGAGSQPEAQRELDVVLRTVIPKTSPHCPLTTPRREIVVQDVLNGTITFLPLEEDDEGNLKVKMSNVYQIQLSHSKEEWFISVLIFCPERWHSDGIVYPKPTWLGEELLAKLAKWSVENKKSDFKSTLSLISIMKYSKAYQELKEKYK----EMVKVWPEVTDPEKFVYEDVAIAAYLLILWEEERAERRLTARQSFVDLGCGNGLLVHILSSEGHPGRGIDVRRRKIWDMYGPQTQ---LEEDAITPNDKTLFPDVDWLIGNHSDELTPWIPVIAARSSYNCRFFVLPCCFFDFIG-RYSRRQSKKTQYREYLDFIKEVGFTCGFHVDEDCLRIPSTKRVCLVGKSRTYPSSREASVDEKRTQYIKSRRGCPVSPPGWELSPSPRWVAAGS--AGHCDGQQALDARVGCVTRAWAAEHGAGPQAEGPWLPGFHPREKAERVRNCAALPRDFIDQVVLQVANLLLGGKQLNTRSSRNGSLKTWNGGESLSLAEVANELDTETLRRLKRECGGLQTLLRNSHQVFQVVNGRVHIRDWREETLWKTKQPEAKQRLLSEACKTRLCWFFMHHPDGCALSTDCCPFAHGPAELRPPRTTPRKKIS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHB9-1", "uniprot_id": "TRM44_DROME", "id": "Q9VHB9-1", "name": "Probable tRNA (uracil-O(2)-)-methyltransferase", "aln": "--------------------------MAAVEEAQFWQAIGILIKNYHALNKKIFEVVITQVTKQQN--------------------------------------------------------------------------------GRVCESSAEELAMSLKEDPSQRTCTG----------------------------------FTIGFKLLSKKLAENILGTGIVDFENC--------------LYECQFASDSIEGFSVGLLGGEFKLKSK----SNTNWLEFVLRPKLLSWSQSKQDEAKVKSLGLVNVEKYNDLYKELKQRHSQRLLEHWKTAQESTDPLKFIYEDLAIAAYLIVLWSQTQSEP-----TAFADLGCGNGLLVHVLNAEGYKGYGYDIRKRKLWSLYPPDTQRSLIEKAVEPNSFRLDFPGVDWLIGNHSDELSPWLPVLAGR--LNINYFLLPCCPFELSGAKFRRRNTKISAYQDFFQYVTQVSHECGYEILQDRLKIPSTKRLALLGIKRKASKAIEDLEYFVQEELRKYKTGDAK----------------------------------------------------------IKLREKEESVRNCTQVDKTIIDGLVFKIFKLILDSNED-----------KWSG--RLPMREIAQALTKEELSGIKSECGGIKTLLRNKHEVFEFCGGDLIG--------IRTPKPTATLPKSHLTIKKRSCFFKLHHPLGCPLDDAECSFIH------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02648-1", "uniprot_id": "TRM44_YEAST", "id": "Q02648-1", "name": "tRNA (uracil-O(2)-)-methyltransferase", "aln": "-MTGDGSAHISKNNQNQHKDRFKFIVNDKSILGPQWLSLYQTDGKVTFAKSHFEQAMMNVIREPNINSTVILR----------------------------------------------------ADILKEINHAAEAGSEPKFDESVLKKFEIDNGNESGEEDVKKINIEDLNIRSCETSESLKLSPVHEFVRRIIPRNFYKDAIINQTCLILNSKDPNFQETSLIVYTPHINSEKDCPFYIPRTQSVGILLHQSVLSVHYIPFPEDKTAFTDESERVVRTAYRLLQTANKHSKGVMQG-YEKRVNHDQVVNKVNFQNTYIVLKKKYS---KFLVENWAESTDPKKHVFEDIAIAAFLIELWIK-VYGPDFRSKMQFRDLGCGNGALCYILLSESIKGLGIDARKRKSWSIYPPEVQSSLKEQVIIPSILLRPHPALKRQVP-HLEHNGRFFPVKVTHEVIAPATVVYSSEDLLKSP----QVNTAEFPPDTFIIGNHSDELTCWIPLLGHPYMVIPCCSHNFSGQRVRFNVRKRSPRSNEIKNQNNSKSTYSG----------------------------------------------------------LVDHVEYISSRVGWKVEKEMLRIPSTRNAAIIG------------------------VENATLKHFPTQAVYDMIWEDGGAEGWIQNTMSLLKRNPRNH-----------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: . :.:: . : . : . .. . : . : : . . . : .. .. : * . . . ::. .: * **::: : * *** *.::**:***::*: ** : * ******* * ::* *. * * * *:** *.:* *:.* *: . .* :. : * :. ::** . : .: .. : : :: :: . * : . : . : * . . : : . : : : * : : :: : :: : .: : : * ** : ::*. .::: ", "identical_positions": 51, "similar_positions": 112, "identity": "6.51%" }, { "cls_id": "homologset.agr.SGD:S000005952", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49615-1", "uniprot_id": "CDK5_MOUSE", "id": "P49615-1", "name": "Cyclin-dependent kinase 5", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFD-----SCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPG-NDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKPY-PMYPATTSLVNVVPKLNATGRD-----LLQNLLKCNPVQRISAEEALQHPYFSDFCPP--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03114-1", "uniprot_id": "CDK5_RAT", "id": "Q03114-1", "name": "Cyclin-dependent kinase 5", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFD-----SCNGDLDPEIVKSLLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPG-NDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKPY-PMYPATTSLVNVVPKLNATGRD-----LLQNLLKCNPVQRISAEEALQHPYFSDFCPP--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00535-1", "uniprot_id": "CDK5_HUMAN", "id": "Q00535-1", "name": "Cyclin-dependent kinase 5", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFD-----SCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPG-NDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPY-PMYPATTSLVNVVPKLNATGRD-----LLQNLLKCNPVQRISAEEALQHPYFSDFCPP--------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48609-1", "uniprot_id": "CDK5_DROME", "id": "P48609-1", "name": "Cyclin-dependent kinase 5 homolog", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVRLIDVLHSDKKLTLVFEHCDQDLKKYFD-----SLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAELADAGRPLFPG-SDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVAL-PSFPAITSWSQLVPRLNSKGRD-----LLQKLLICRPNQRISAEAAMQHPYFTDSSSSGH------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O94921-1", "uniprot_id": "CDK14_HUMAN", "id": "O94921-1", "name": "Cyclin-dependent kinase 14", "aln": "--------------MCDLIEPQPAEKIGKMKKLRRTLSESFSRIALKK---DDTTFDEICVTKM----------------STRNCQGMDSVIKPL--------DTIPEDKK--------------VRVQRTQSTFDPFEKPA------NQVKRVHSENN----------------------ACINFKTSSTG-KESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEE-EGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMD-----KHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQ-GVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHA---EDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96Q40-1", "uniprot_id": "CDK15_HUMAN", "id": "Q96Q40-1", "name": "Cyclin-dependent kinase 15", "aln": "------------------------------------MGQELCAKTVQP---GCSCY--HCSEGG----------------EAHSCR----RSQPE--------TTEAAFKL--------------TDLKEASCSMTSFHPRG------LQAARAQKFKS----------------------KRPRSNSDCFQ-EEDLRQGFQWRKSLP----FGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAE-EGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMS-----QHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQ-GQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEA---EDLASQMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDEESLFTVSGVRLKPEMCDLLASYQKG-HHPAQFSKCW-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PE01-1", "uniprot_id": "M9PE01_DROME", "id": "M9PE01-1", "name": "cyclin-dependent kinase", "aln": "MATTTTTTTTTGATNAKDGVTMREKKGGALQKLKKRLSHSFGRLTISREDGDESTHHHHHHHHHRGGHGGHHNHGNKVPYNGYNSEEYLDRLEPN--------GNIPADKTNCRYGAQESAKNDNNKPQDWRSTDSTDHHDR------VQRQLSVSSDSKLLDEDIREEMKYHSHVVMRPKKPPRPKSEVFLNKQETHPRRKRFSAFGGDSPFGKQEAYVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQEE-EGAPFTAIREASLLKELKHSNIVTLHDIVHTRETLTFVFEYVNTDLSQYME-----KHPGGLDHRNVRLFLFQLLRGLSYCHKRRVLHRDVKPQNLLISDCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEMVT-GMPTFPGIRDTYDQLDKIFKLLGTPTEDTWPGVTHFPGYKPHKLGFYRPRKLGHNFPRLYDIIEG---ETIANGFLQLNPEQRLGADDALQHPYFAQLPKKLYELPDETSIFTVEGVQLYTEPNRQNKXKLKQVLSVDGVRFYC-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17157-1", "uniprot_id": "PHO85_YEAST", "id": "P17157-1", "name": "Cyclin-dependent protein kinase PHO85", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSSSQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMIT-GKPLFPGTNDE-EQLKLIFDIMGTPNESLWPSVTKLPKYNPN-IQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFAEYYHHAS------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q04899-1", "uniprot_id": "CDK18_MOUSE", "id": "Q04899-1", "name": "Cyclin-dependent kinase 18", "aln": "----------------MNKMKNFKRRLSLSVPRPETIEESLAEFTEQFNQLHTQTNE---------------------------------------------------------------------DGTDEPEQLSPGMQYQ-----QRQNQRRFSMEDLN--------KRLSLPMDIRLPQEFLQKLQLENPGLPKPLTRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLD-----HCGNLMNMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCILYEMAT-GKPLFPG-STVKEELHLIFRLLGTPTEESWPGVTSISEFRAYNFPRYLPQPLLSHAPRLDTEGIN-----LLSSLLLYESKSRMSAEAALNHPYFQSLGDRVHQLHDTASIFSLKEIQLQKDPGYRGLAFQHPGRGKSRRQSIF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35832-1", "uniprot_id": "CDK18_RAT", "id": "O35832-1", "name": "Cyclin-dependent kinase 18", "aln": "----------------MNKMKNFKRRLSLSVPRPETIEESLTEFTEQFNQLHTQRNE---------------------------------------------------------------------DGRDEPGQLSPGVQYQ-----QRQNQRRFSMEDLN--------KRLSLPMDIRLPQEFLQKLQLENPGLPKPLTRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLD-----HCGNLMNMHNVKIFMFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCILYEMAT-GKPLFPG-STVKEELHLIFRLLGTPTEESWPGVTSISEFRAYNFPRYLPQPLLSHAPRLDTEGIN-----LLTSLLLYESKSRMSAEAALSHPYFQSLGERVHQLDDTASIFSLKEIQLQKDPGYRGLAFQHPGRGKSRRQSIF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07002-2", "uniprot_id": "CDK18_HUMAN", "id": "Q07002-2", "name": "Cyclin-dependent kinase 18", "aln": "--------------MIMNKMKNFKRRFSLSVPRTETIEESLAEFTEQFNQLHNRRNENLQLGPLGRDPP------------------------------------------------QECSTFSPTDSGEEPGQLSPGVQFQ-----RRQNQRRFSMEDVS--------KRLSLPMDIRLPQEFLQKLQMESPDLPKPLSRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLD-----HCGNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMAT-GRPLFPG-STVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSFPCYLPQPLINHAPRLDTDGIH-----LLSSLLLYESKSRMSAEAALSHSYFRSLGERVHQLEDTASIFSLKEIQLQKDPGYRGLAFQQPGRGKNRRQSIF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q00537-1", "uniprot_id": "CDK17_HUMAN", "id": "Q00537-1", "name": "Cyclin-dependent kinase 17", "aln": "-------------------MKKFKRRLSLTLRGSQTIDESLSELAEQMTIEENSSKDNEPIVKNGRPPTSHSMHSFLHQYTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDGESDQASGTSSDEVQSPTGVCLRNRIHRRISMEDLN--------KRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMD-----DCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMAS-GRPLFPG-STVEDELHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYKPQPLINHAPRLDSEGIE-----LITKFLQYESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGHGKNRRQSMLF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ::: :*:*:*.**:*. .: . **** : :: : **.* :*:** .*:* *** *** * *::*: ..**:***. . ** :*:. : : : *:*:**.: * . :****:*******. *:***.******* .:* . :* ********.**.*:*: *:: :*:*. *** *: * . *** ::* *: ::*.*.:. **.: : : :* . *:.*. *: * :* ", "identical_positions": 99, "similar_positions": 82, "identity": "17.58%" }, { "cls_id": "homologset.agr.SGD:S000005958", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96K17-1", "uniprot_id": "BT3L4_HUMAN", "id": "Q96K17-1", "name": "Transcription factor BTF3 homolog 4", "aln": "-------------------------------------------------MNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQSSLKKLAVNNIAGIEEVNMIKDDGTVIHFNNPKVQASLSANTFAITGHAEAKPITEMLPGILSQLGADSLTSLRKLAEQFPRQVLDSKAPKPEDIDEEDDDVPDLVENFDEASKNEAN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A3I4-1", "uniprot_id": "D4A3I4_RAT", "id": "D4A3I4-1", "name": "Transcription factor BTF3", "aln": "-------------------------------------------------MNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQSSLKKLAVNNIAGIEEVNMIKDDGTVIHFNNPKVQASLSANTFAITGHAEAKPITEMLPGILSQLGADSLTSLRKLAEQFPRQVLDSKAPKPEDIDEEDDDVPDLVENFDEASKNEAN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQH7-1", "uniprot_id": "BT3L4_MOUSE", "id": "Q9CQH7-1", "name": "Transcription factor BTF3 homolog 4", "aln": "-------------------------------------------------MNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQSSLKKLAVNNIAGIEEVNMIKDDGTVIHFNNPKVQASLSANTFAITGHAEAKPITEMLPGILSQLGADSLTSLRKLAEQFPRQVLDSKAPKPEDIDEEDDDVPDLVENFDEASKNEAN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PC91-1", "uniprot_id": "BT3L4_DANRE", "id": "Q6PC91-1", "name": "Transcription factor BTF3 homolog 4", "aln": "-------------------------------------------------MNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQSSLKKLVVNNIAGIEEVNMIKDDGTVIHFNNPKVQASLSANTFAITGHAETKQLTEMLPGILSQLGADSLTSLRKLAEQFPRQVLDNKAPKAEDIDEEDDDVPDLVENFDEASKNEAN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20290-1", "uniprot_id": "BTF3_HUMAN", "id": "P20290-1", "name": "Transcription factor BTF3", "aln": "MRRTGAPAQADSRGRGRARGGCPGGEATLSQPPPRGGTRGQEPQMKETIMNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKAPLATGEDD-DDEVPDLVENFDEASKNEAN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0R5M7-1", "uniprot_id": "M0R5M7_RAT", "id": "M0R5M7-1", "name": "Transcription factor BTF3", "aln": "--------------------------------------------MKETIMNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNSISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKAPLAAGEEE-EDEVPDLVENFDEASKNEAN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64152-1", "uniprot_id": "BTF3_MOUSE", "id": "Q64152-1", "name": "Transcription factor BTF3", "aln": "MRRTGAPTQADSRGRGRARGGWPGAEATPSLP--LGGSRGRESQMKETIMNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKAPLATGEDD-DDEVPDLVENFDEASKNEAN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7KM15-1", "uniprot_id": "Q7KM15_DROME", "id": "Q7KM15-1", "name": "Transcription factor BTF3", "aln": "-------------------------------------------------MNAEKLKKLQAQVRIGGKGTPRRKKKIVHSTPATDDKKLQSSLKKLSVNTIPGIEEVNIIKNDGTVIHFNNPKAQASLPTNTFAITGHGENKTITEMVPGILTQLGPQDINQLKKLATEIASKSGAGGAAGSSAADAGDDDVPDLVENFEEVAIADTKEE------KSGEVAASA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPR2-1", "uniprot_id": "Q9VPR2_DROME", "id": "Q9VPR2-1", "name": "Transcription factor BTF3", "aln": "-------------------------------------------------MNVEKLKRLQAQVRIGGKGTPRRKKKVMHQTAATDDKKLQSSLKKLSVSTIPGIEEVNIIKDDLTVIHFNNPKAQASLSANTFAVTGHGETRKVVEMLPDILPQLGQETVVQLRMYANAMNSQKGAPGSGDGPLPAEEDDDVPLLVGDFDEVAKVEATKQPVHEPKESAEIKAKDKQQQQPKKEQKQSAKVPETTNPSENPKEKQENKKGQAKNNKKGDPQTNKDKTNKSKDQAKGQPAPQANKETTQAAQALKQNPSKPAVQQKKDQVLAVDQKIEANGAIQKAQQPKPAETKSTDQKVEPKSAEKQVDKAKPIEQTKTKESKVEHPKPAQKQLDQNTQAKPTAERSEAKPVVPTPEPQKSAPPAVQTLAQIVALPAEKPANEAVAAPKAEEQKKDSSGPAKVEPAITPSAPQPVTTAEPPKSALKQDSPPKSAPKQGSPPKNVPKQESPPQSAPKQDSPPKGAPKQDSPPKGAPKQDSPPKGAPKQDSAPQQKTPPPVKQEVAPAKQDEPPAKQDAPPAKQDAPVPVPEVIKTLAPEVPNVSQAPAQPQGQAALASEKPADAPKAIEEPKAAPKKESPPPTKPVTATVPVAPATPAEAPSPLAPSTPPSTPTSVPPSAATVTPPSPATVTPPSPAVVTPPQKQSAAPQAGIKKQEAGTKTKQQQPANKPQQPQKQPPGGAGGSAGPGGNKGVQKQPNPNAKPAVAPKPAQATPKPAAASPKASPNQTNPQQQQGKAANKASPPKQTGPTGGQQKSAANASKATASPKSAASPKATSPKAGTPTNPASASGGPN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02642-1", "uniprot_id": "NACB1_YEAST", "id": "Q02642-1", "name": "Nascent polypeptide-associated complex subunit beta-1", "aln": "--------------------------------------------MPIDQEKLAKLQKLSANNKVGGTRRKLNKKAGSSAGANKDDTKLQSQLAKLHAVTIDNVAEANFFKDDGKVMHFNKVGVQVAAQHNTSVFYGLPQEKNLQDLFPGIISQLGPEAIQALSQLAAQMEKH----EAKAPADAEKKDEAIPELVEGQTFDADVE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** :*.*: ::**. .** . **.*** .* ** . .* .: *.*::.:: .*:***: .*.: ** .. * : : : ::.*.*: *** : : * * : : : :: :* ** . : : ", "identical_positions": 37, "similar_positions": 48, "identity": "4.38%" }, { "cls_id": "homologset.agr.SGD:S000005961", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K261-1", "uniprot_id": "A0A0G2K261_RAT", "id": "A0A0G2K261-1", "name": "Isoleucine--tRNA ligase, mitochondrial", "aln": "MLWGLHPHGPGTAALTAAGSLWGPARFPSRLGCLGMTRRLVVRSVAGADSPQSSPKSGRYRDTVLLPQTNFPMKLLGHQQSDME-LEIQQKCGFSELYSWQRER-KVKTEFCLHDGPPYANGDPHVGHALNKILKDIVNRFHMMRGSKVHFVPGWDCHGLPIETKVLSEL-GVNTQTLSAMEIREKARSFAQAAIEKQKSAFARWGVMADWS--NCYYTFDPKYEAKQLRVFQQMYEKGLVYRSYKPVYWSPSSRTALAEAELEYNPEHVSRSVYVRFPLLKPPPTLESLTG---ASSPVSALVWTTQPWTVPANQAICYMPEAKYAVVKCS--ASGNFYILAEDKISPVASALETTFDVTATFSGVDLEGGTCSHPLIPDKVS-PLLPATHVTMAKGTGLVHTAPAHGMEDYSVASQHSLPMDCLVDEEGMFTSAAGPELQNKAVLTEG-------------TDVVIKMLQATKNLLKEESIVHSYPCDWRTKKPVLIRASKQWFVNIMDIKATAKESLKTVKFIP----GAALNSMMDMLDRRPYWCISRQRVWGVPIPVFHHKTK-DEYLINSQTTEHIIKLVEQHG-SDVWWTLPAEKLLPEEVVAQAGGPGALEYVPGQDILDIWFDSGTSWSCVLQGTEQRADL----------YLEGKDQLGGWFQSSLLTSVATR--SKAPFRTVMVHGFTLGEKGEKMSKSLGNVIDPDTIISGGKDHSKEPPYGADILRWWIAES-NVFTEVTIGPSVLSAARDDISKLRNTLRFLLGNLAGFNPETASVPVKNMYIIDQYMLHLIQDFATKVTDSYKQYDFGKVVRLLKAFYTRELSSFYFSIVKDRLYCESETDPKRRSCQTALAEILDVLVRSFAPVLPHLAEEVFQHIPYVKEPKSVFRTGWISTSSVWKKPGLEEAVESACAMRDSFLGSIPGKNAAEYDVIIVIEPGLLFEIMEMLQA--EETSSTSQLNELMMASQTTLLAQEPRERSADAIELTGTFVINLEGQNLTR------VRIVEGRRALGRSVQ----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BIJ6-1", "uniprot_id": "SYIM_MOUSE", "id": "Q8BIJ6-1", "name": "Isoleucine--tRNA ligase, mitochondrial", "aln": "MHWGLCPRGPGAAAVAAAGSFWGPARLPSRLGCLGMTRRLVVRSVAGADSPQSSSKGGRYRDTVLLPQTSFPMKLLGRQQSDME-LEIQQKCGFSELYSWQRER-KVKTEFCLHDGPPYANGDPHVGHALNKILKDIANRFHMMRGSKVHFVPGWDCHGLPIETKVLSEL-GVDAQSLSAMEIREKARSFAQAAIEKQKSAFVRWGVMADWN--NCYYTFDPKYEAKQLRVFYQMYEKGLVYRSYKPVYWSPSSRTALAEAELEYNPEHVSRSIYVRFPLLRPPPKLESLTD---ASSPVSVLVWTTQPWTIPANQAICYMPEAKYAVVKCS--ASGHLYILAEDKIAPVASALETTFDVVAAFSGVDLEGGTCSHPLTPDKVS-PLLPATHVTMAKGTGLVHTAPAHGMEDYSVASQHSLPMDCLVDEGGMFTDAAGPELQNKAVLKEG-------------TDVVIKMLQATKNVLKEENIVHSYPCDWRTKTPVLIRASKQWFVNITDIKAAAKESLKTVKFIP----GAALNSMTDMLDRRPYWCISRQRVWGVPIPVFHHKTK-DEYLINSQTTEHIIKLVEQHG-SDVWWTLPAEQLLPAEVLAQAGGPGALEYAPGQDILDIWFDSGTSWSCVLQDTQQRADL----------YLEGKDQLGGWFQSSLLTSVATR--SKAPFRTVMVHGFTLGEKGEKMSKSLGNVINPDTIISGGKDHSKEPPYGADILRWWIAES-NVFTEVTIGPSVLSAARDDISKLRNTLRFLLGNLTGFNPETDSVPVKNMYVIDQYMLHLIQDFATKITDSYKQYDFGKVVRLLKAFYTRELSSFYFSIVKDRLYCENEKDPKRRSCQTALAEILDVLVRAFAPILPHLAEEVFQHIPYVTEPKSVFRTGWINTSSIWKKPGLEEAVESACAMRDSFLGSIPGKNAAEYEVIIVIEPGLLFEIMEMLQA--EETSSTSQLNELMMASQTTLLAQEPRERTAGDIELTGTFVINLEGGDIREESSYKVIVVPTAREKCPRCWKHTSETADALCPRCAEVIGAK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NSE4-1", "uniprot_id": "SYIM_HUMAN", "id": "Q9NSE4-1", "name": "Isoleucine--tRNA ligase, mitochondrial", "aln": "MRWGLRPRGPGAAALATARSLWGTPRLPCSPGWQGATKRLLVRSVSGASNHQPNSNSGRYRDTVLLPQTSFPMKLLGRQQPDTE-LEIQQKCGFSELYSWQRER-KVKTEFCLHDGPPYANGDPHVGHALNKILKDIANRFHMMNGSKIHFVPGWDCHGLPIEIKVLSEL-GREAQNLSAMEIRKKARSFAKAAIEKQKSAFIRWGIMADWN--NCYYTFDGKYEAKQLRTFYQMYDKGLVYRSYKPVFWSPSSRTALAEAELEYNPEHVSRSIYVKFPLLKPSPKLASLID---GSSPVSILVWTTQPWTIPANEAVCYMPESKYAVVKCS--KSGDLYVLAADKVASVASTLETTFETISTLSGVDLENGTCSHPLIPDKAS-PLLPANHVTMAKGTGLVHTAPAHGMEDYGVASQHNLPMDCLVDEDGVFTDVAGPELQNKAVLEEG-------------TDVVIKMLQTAKNLLKEEKLVHSYPYDWRTKKPVVIRASKQWFINITDIKTAAKELLKKVKFIP----GSALNGMVEMMDRRPYWCISRQRVWGVPIPVFHHKTK-DEYLINSQTTEHIVKLVEQHG-SDIWWTLPPEQLLPKEVLSEVGGPDALEYVPGQDILDIWFDSGTSWSYVLPGPDQRADL----------YLEGKDQLGGWFQSSLLTSVAAR--KRAPYKTVIVHGFTLGEKGEKMSKSLGNVIHPDVVVNGGQDQSKEPPYGADVLRWWVADS-NVFTEVAIGPSVLNAARDDISKLRNTLRFLLGNVADFNPETDSIPVNDMYVIDQYMLHLLQDLANKITELYKQYDFGKVVRLLRTFYTRELSNFYFSIIKDRLYCEKENDPKRRSCQTALVEILDVIVRSFAPILPHLAEEVFQHIPYIKEPKSVFRTGWISTSSIWKKPGLEEAVESACAMRDSFLGSIPGKNAAEYKVITVIEPGLLFEIIEMLQS--EETSSTSQLNELMMASESTLLAQEPREMTADVIELKGKFLINLEGGDIREESSYKVIVMPTTKEKCPRCWKYTAESSDTLCPRCAEVVSGK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VUY4-1", "uniprot_id": "Q9VUY4_DROME", "id": "Q9VUY4-1", "name": "isoleucine--tRNA ligase", "aln": "---------------------------MLRIFYFRVGNRLYSMKAAKKDAK-------KYTDTINLPKTKFPNRLTAAKREEQERLVLENKIAVSYAYQEQRLAEKGKPTFVLHDGPPYANGQLHMGHAVNKILKDITLRQRVAHGQRVNYIPGWDCHGLPIELKATS-----TAPGQSAQEIRQKSRAFAWEAIKSQKEEFSSWGILANWQKDNIYMTFQPEFIVNQLEMFYNLYEKGLVYRDLKPVYWSPSSRTALAEAELEYDANHISPSVYVRFALNP-----SSFDV---KDKQIYALVWTTTPWTLPSNQAICYNASLEYVIVRLSDRNQDELYLMASALMADFEANTQLKCEIVQHLSGELLSKLSYNHPIDKEQSNLPFFDASHVQDSKGTGLVHTAPAHGPEDFLVSLTQKIPVKCFVNEEGTYTKEAPDFLRGKSVLDQG-------------NSLVLD--RIAEDVVHSSKLEHSYPIDWRTKKPVIIRASEQWFINTEKLKTPAADALEQVEIYPRANAEASKKALLTQLQKRPYWCISRQRAWGVPIPVLYSRES-GKVVLNSALIEHLCNLLRKEGSIDFWWVKSVEELVPEHLLRELH-HEAKDLVKGTDILDIWFDSGSTWSAVL-GKDKIADL----------YLEGYDQFTGWFQSSLLMSIAAR--ECAPYKALFVHGFTVDEKGYKMSKSLGNVISPKQITK---------KYGTDALRWWVASHGTQHMSITVSDKLLQQAAENLCKIRGTMRYLKGVIGEKQSGEKLIRTSDKSYLNRYLLSQLVEFESEVEKLYQAYEYNRVVACVQNFIANQVSAVYVHLIKDRLYCG--DDHELLAIRQTLTHCYQQLCKSLWPIVPFLVEESWS---YYDTTGGAFHEQIVQTNPEWQDTKATEVINAAFDVKRLINQQAGDVNTWHLAVTIKGKERSQLDLLRELHSPLGESVSNSELCEILQVGSVTLLQSHN---SDLDIALS-KLQISL----------------------CPRCRRYGLEDEQKTCQRCSDVMEAKN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48526-1", "uniprot_id": "SYIM_YEAST", "id": "P48526-1", "name": "Isoleucine--tRNA ligase, mitochondrial", "aln": "---------------------MKRSRLVPQHIFSIISKRYLAKHAYQKTLNLP---KTKFPNRSNLEITLRELIPKSSQLVYKEQLRDFFEEFSKLNTTDEKLEFIKEKLFILHDGPPYANGELHLGHALNKILKDIINRYQLSQGKYIFYKPGWDCHGLPIEIKALKDLSAQQIESISPLKIRSMALKHAQKAIKRQRETFQHFAILTDWET--PYLTMDKDYEINQLNIFKEMYERGLIKRQNKPVYWGTETRTALAEGELEYNENHKSIAAYVKFPLEKKSQMDLCKKLGITNNLPIYCLIWTSTPWTLLSNRAICFNQDFSYSLLRLN-----SELILVETGSIDKLGLTTNSFETIKQFQGTHLNGLYYQNLLVDDKVGRPLLHGAHVTSGTGTGLVHTAPGHGQDDYLIGIQNGLEIYSPVDHQGRYQLNELPQSVRSIVRDEGDLTKGRQVLDAETAKIILCKLSDLNLLYKSHEYTHSYPYDWRSKKPVIIRATPQWFADLHDVKNLALESISRVKFCP----KRGYSRLSSFMKSRNEWCISRQRSWGIPILSFYKKSEPDSVLMNSEILAHAIEKIKQKG-INAWFNDKDNDMK--EWLPEKYHDVAHEYCRSQDTMDVWFDSGSSWSVIKDFYEKSLKLSKLPSPLYQVCLEGSDQHRGWFQSSLLTKVASSNVPVAPYEEVITHGFTLDENGLKMSKSVGNTISPEAIIRGDENLG-LPALGVDGLRYLIAQS-NFTTDIVAGPTVMKHVGEALKKVRLTFRYLLSNLQKSQ-DFNLLPIEQLRRVDQYTLYKINELLETTREHYQKYNFSKVLITLQYHLNNELSAFYFDISKDILYSNQISSLARRQVQTTLVHILNAYRAILAPILPVMVQEVWK---YIPEGWLQGQEHIDINPMRGKWPFLDSNTEIVTSFENFELKILKQFQEEFKRLSLEEGVTKTTHSHVTIFTKHHLPFSSDELCDILQSSAVDILQMDDNNNSLPTIELGSGINVQILVERSKR-------------HNCPRCWKANSAEEDKLCDRCKEAVDHLMS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* . :: : * * . : * * : . :: : * **********: *:***:******* * :: .*. : : *********** *. . *. :**. : .* **: *:. * :.::::*. * *:: .: :**. * ::*::**: *. ***:*...:******.****: :* * : **:*.* . . : *:**: ***: :*.*:*: . .* ::: . ::. . . : :.* *. .: : :: . *:: . ** ..*********.** :*: :. : : : . *:. * : . * :* .::: : : :. . **** ***:*.**:***: *** : .:* * : :. *:: * . . : :. * ******* **:** :: : . .. ::** * : :.:.* : *: :.: . : : * : . * :*:*****::** : :: .* *** ** ******** .:*: **:. ::.****:.*:* *****:**.* *. : *.* **: :*. . .:. . .::. . : : *:* *:*:* . : : : .: :::* * : :: . *: *::.:*: :: . .::* .*. : ** **. . : :*.. : : *::* :.:* :. * : . : . . : . .. : : . : : . *..:* ::: . :* . : * * : :.: *. : ", "identical_positions": 221, "similar_positions": 277, "identity": "20.87%" }, { "cls_id": "homologset.agr.SGD:S000005963", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R3L8-1", "uniprot_id": "CDK8_MOUSE", "id": "Q8R3L8-1", "name": "Cyclin-dependent kinase 8", "aln": "-----------MDYDFKVKLSSERERVEDLFEYEGCKVG-------------------------------------------RGTYGHVYKAKRKDGK---------------------------------------------------------------------------------------DDKDYALKQIEGTGISMSACREIALLRELKHPNVISLLKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCR--QEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSD-VFAGCQIPYPKREFLTEEEPDEKGDKKTQQQ-----------------------QQGNNHTNGTG-------------HPGNQDSGHAQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPN--------PGPSTSQPQSS--------------------------------MGYSATS--QQPPQYSHQTHRY--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49336-1", "uniprot_id": "CDK8_HUMAN", "id": "P49336-1", "name": "Cyclin-dependent kinase 8", "aln": "-----------MDYDFKVKLSSERERVEDLFEYEGCKVG-------------------------------------------RGTYGHVYKAKRKDGK---------------------------------------------------------------------------------------DDKDYALKQIEGTGISMSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCR--QEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSD-VFAGCQIPYPKREFLTEEEPDDKGDKKNQQQ-----------------------QQGNNHTNGTG-------------HPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPN--------PGPSTSQPQSS--------------------------------MGYSATS--QQPPQYSHQTHRY--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JH47-1", "uniprot_id": "CDK8_DANRE", "id": "Q8JH47-1", "name": "Cyclin-dependent kinase 8", "aln": "-----------MGYDFKVKLTGERERVEDLFEYEGCKVG-------------------------------------------RGTYGHVYKAKRKDGK---------------------------------------------------------------------------------------DDRDYALKQIEGTGISMSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPLQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLSNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCR--QEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIRRITSEQAMQDPYFLEEPLPTSD-VFAGCQIPYPKREFLTEEEPEDKADKKNQQQ-----------------------QQGNNHTNGAG-------------HTGNPDNSHAQGPPLKKVRVVPPTATSSGLIMTSDYQRSNPHAAYQN--------PGPSTSLPQSS--------------------------------MGYSSTS--QQPPQYSHQTHRY--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I5ZVW8-1", "uniprot_id": "A0A8I5ZVW8_RAT", "id": "A0A8I5ZVW8-1", "name": "Cyclin-dependent kinase 8", "aln": "-----------MDYDFKVKLSSERERVEDLFEYEGCKVG-------------------------------------------RGTYGHVYKAKRKDGK---------------------------------------------------------------------------------------DDKDYALKQIEGTGISMSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCR--QEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSD-VFAGCQIPYPKREFLTEEEPDEKGDKKNQQQ-----------------------QQGNNHTNGTG-------------HPGNQDSGHAQGPPLKKVRVVPPTTTSAFQSTCCLSQPWTKHITAPEQHGILSYLPAASTVLTSDTSVLSCAGVCPCTVAHAAGLAAALCGNLVWAMRMYCTTTSS-QCPVAEFHSCHRSGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BWD8-1", "uniprot_id": "CDK19_MOUSE", "id": "Q8BWD8-1", "name": "Cyclin-dependent kinase 19", "aln": "-----------MDYDFKAKLAAERERVEDLFEYEGCKVG-------------------------------------------RGTYGHVYKARRKDGK---------------------------------------------------------------------------------------DEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCR--QEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLD-VFAGCQIPYPKREFLNEDEPEEKGDKNQPQQQNPHQQPAAPAQQTAAPPQAPPPQQSSAQTNGTAGGATAGGGGAGAGLQHSQDPGLNQVPPNKKPRIGPSGANSGGPVMPSDYQHSSSRLNYQS--------SVQGSSQSQST--------------------------------LGYSSS-QQSTQYHSSHQTHRY--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZDM6-1", "uniprot_id": "D3ZDM6_RAT", "id": "D3ZDM6-1", "name": "cyclin-dependent kinase", "aln": "-----------MDYDFKAKLAAERERVEDLFEYEGCKVG-------------------------------------------RGTYGHVYKARRKDGK---------------------------------------------------------------------------------------DEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCR--QEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLD-VFAGCQIPYPKREFLNEDEPEEKGDKNQPQQQNPHQQPVAPQQQAAAPTQAPPPQQSSAQTNGTAGGATTGGGAAGAGLQHSQDSGLNQVPPNKKPRIGPSGANSGGPVMPSDYQHSSSRLNYQS--------SVQGSSQSQGT--------------------------------LGYSSS-QQSTQYHPSHQAHRY--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BWU1-1", "uniprot_id": "CDK19_HUMAN", "id": "Q9BWU1-1", "name": "Cyclin-dependent kinase 19", "aln": "-----------MDYDFKAKLAAERERVEDLFEYEGCKVG-------------------------------------------RGTYGHVYKARRKDGK---------------------------------------------------------------------------------------DEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCR--QEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLD-VFAGCQIPYPKREFLNEDDPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGTGAGLQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDYQHSSSRLNYQS--------SVQGSSQSQST--------------------------------LGYSSSSQQSSQYHPSHQAHRY--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QLR0-1", "uniprot_id": "A0A8M1QLR0_DANRE", "id": "A0A8M1QLR0-1", "name": "cyclin-dependent kinase", "aln": "-----------MDYDFKTKLAAERERVEDLFEYEGCKVG-------------------------------------------RGTYGHVYKAKRKDGK---------------------------------------------------------------------------------------DEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCR--QEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFLEDPLPTSD-VFAGCQIPYPKREFLSEDEPEEKAEKNQTQQ---HQQTAA---QTQTQTQQAPTQQSSAQTNGTSGTAGAN---TGPSMQHGQD----QGPPNKKTRT------SGTGVHQTDYQHSSSRLGYQS--------NIQGSTQSQST--------------------------------MGYSSS------SQHSHQSHRY--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VT57-1", "uniprot_id": "CDK8_DROME", "id": "Q9VT57-1", "name": "Cyclin-dependent kinase 8", "aln": "-----------MDYDFKMKTQIERTKVEDLFNYEGCKVG-------------------------------------------RGTYGHVYKAKWKETS---------------------------------------------------------------------------------------DGKEYALKQIDGTGLSMSACREIALLRELKHQNVITLIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCR--QEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIKKMPEHHTLTKDFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDQYFQEEPQPTQD-VFAGCPIPYPKREFLTDDDQEDKSDNKRQQQ-----------------------QQQQQQQQQQQ--------------QQQQQQQQQQQQQQMNAEPNAKRVRLSGAGNQQDFHHQQQQQQQQQ----------QQQQQQQQQ--------------------------------MMFNQQ----------QNFQRFN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39073-1", "uniprot_id": "SSN3_YEAST", "id": "P39073-1", "name": "Meiotic mRNA stability protein kinase SSN3", "aln": "MYNGKDRAQNSYQPMYQRPMQVQGQQQAQSFVGKKNTIGSVHGKAPMLMANNDVFTIGPYRARKDRMRVSVLEKYEVIGYIAAGTYGKVYKAKRQINSGTNSANGSSLNGTNAKIPQFDSTQPKSSSSMDMQANTNALRRNLLKDEGVTPGRIRTTREDVSPHYNSQKQTLIKKPLTVFYAIKKFKTEKDGVEQLHYTGISQSACREMALCRELHNKHLTTLVEIFLER--KCVHMVYEYAEHDLLQIIHFHSHPEKR----MIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDG----CVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIGLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEKYPEYDQITKFPKYR----DNLATWYHSAGGR-DKHALSLLYHLLNYDPIKRIDAFNALEHKYFTESDIPVSENVFEGLTYKYPARRIHTNDNDIMNLGSRTKNN-----------------------TQASGITAGAAAN--------------------ALGGLGVNRRILAAAAAAAAAVSGNNASDEPSRKKNRR---------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : : : * : .:* ****:****: : . . .. .::*:. **:* *****:** ***:: :: :* .:**.: : * :: :****** :**:** .: :* **:*:::*:***: *** *************:* :* ***.*:*:** : *:.* * ****:*************** *:*:*::*******: :***: . : * *.: *:: :**:**:.*:* * :* * :.* **: : * : .* .: . : *.:.: ** :** ** :** : :*::. ** *. *. : ** * ** *.: .::: : .. :: * . : . . : ", "identical_positions": 144, "similar_positions": 114, "identity": "20.93%" }, { "cls_id": "homologset.agr.SGD:S000005964", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CGC6-1", "uniprot_id": "RBM28_MOUSE", "id": "Q8CGC6-1", "name": "RNA-binding protein 28", "aln": "----------------------MAGLTLFVGRLPPSARSDQLEELFSQVGPVKQCFVVTEKGSKACRGFGYVTFSMLEDVQRALKEITTFEGCKIDVTVAKKKLRNKSKETRKNENAESPKKEPKHKKAKVADK------------KARLIIRNLSFKCSE-DDLKAVFTHYGTVLEVNIPKKPDGKMRGFAFVQFKNLLEAGKALKGANMKEIKGRTVAVDWAVAKDKYKDAQHASAPGVKKSSDRKPKESGKKNCRVEEQVEDSDD----EEDDD------SHDDEEE-RESTIASPVSVHKRAVKRAAPEESIEEDDSYEDSDLEEGGSS-YDEGTVDSESSAEDQEDEDVPVSEKKKRKLPSDVTEGKTVFIRNLSFDSEEEALGEVLQQFGDLKYVRVVLHPDTEHSKGCAFAQFMTQEAAQKCLAAASLE---------AEGGGLKLDGRQLKVDLAVTRDEAAKLQTKKVKK--------PTG--TRNLYLAREGLIRAGTKAAEGVSAADMAKRERFELLKHQKLK-NQNIFVSQTRLCLHNLPKAVDDKQLRKLLLEATRGEKGVRIKECRVMRDLKGVHGKMKGQSLGYAFAEFQKHEHALRALRHFNNNPEIFGSQKRPIVEFSLEDRRKLKVKELRIQRSLQKMESKPVTSKPQKEQKEVGKD-KQQKVVQSATQDQSKAPGEQKGKAGSTSWSGFQTKAEVEQVELPDGKKRRKVLALPSHRGPKIRLRDKGKVKSLPSRKPKPQMGQRKQKKQQLASSVQAPKRKAKE------NKAEARFNQLVEQYKQKLLGPSKGAPLMK-------RSKWFDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A5K7-1", "uniprot_id": "D4A5K7_RAT", "id": "D4A5K7-1", "name": "", "aln": "----------------------MLNWRSCQS-LKTSAKP------------------ISVEWSKACRGFGYVTFSMLEDVQRALKEITTFEGCKINVTIAKKKLKNKSKETRKNENSESPKKEPKHKKAKVADK------------KARLIIRNLSFKCSE-DDLKSVFTHYGTVLEVNIPRKPDGKMRGFAFIQFKNLLEAGKALKGANMKEIKGRTVAVDWAVAKDKYKDAQHTSVSGGKKSSERKPKESSKKSCRVEEQVEDDDDDGEDEEDDD------TQDDEDESRDSTVASPVSVRKRAVKRAAPEESTEED-TYDDSDLEEGSSS-YGDGTAHSESSTEELEDEDVPVSKKKKRKLPSDVTEGKTVFIRNLSFDSEEEALGEVLQQFGDLKYVRIVLHPDTEHSKGCAFAQFVTQEAAQKCLAAASPE---------TEGGGLKLDGRQLKVDLAVTRDEAAKLQTKKVKK--------PTG--TRNLYLAREGLIRAGTKAAEGVSAADMAKRERFELLKHQKLK-NQNIFVSQTRLCLHNLPKSVDDKQLRKLLLQATGGEKGVRIKECRVMRDLKAVHGKMKGQSLGYAFVEFQKHEHALRALRHFNNNPETFGPQKRPIVEFSLEDRRKLKVKELRIQRSLQKMGSKPVTSKPQKEQKEQGKD-KQQKAAQGGTRDQSKAPGEQ-GKGRCTSWTGFQTKAEVEQVELPDGTRRRKVLALPSHRGPKVRLRDRGKVKSLPSKKPKPQMGQRKQKKQQSASSLQAPKKKAKE------SKAEAHFNRLVEQYKQKLLGPSKGASLVK-------RSKWFDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NW13-1", "uniprot_id": "RBM28_HUMAN", "id": "Q9NW13-1", "name": "RNA-binding protein 28", "aln": "----------------------MAGLTLFVGRLPPSARSEQLEELFSQVGPVKQCFVVTEKGSKACRGFGYVTFSMLEDVQRALKEITTFEGCKINVTVAKKKLRNKTKEKGKNENSECPKKEPKAKKAKVADK------------KARLIIRNLSFKCSE-DDLKTVFAQFGAVLEVNIPRKPDGKMRGFGFVQFKNLLEAGKALKGMNMKEIKGRTVAVDWAVAKDKYKDTQSVSAIGEEKSHESKHQESVKKKGREEEDMEEEENDDDDDDDDEEDGVFDDEDEEEENIESKVTKPVQIQKRAVKRPAPAKSSDHS--EEDSDLEESDSIDDGEELAQSDTSTEEQEDKAVQVSNKKKRKLPSDVNEGKTVFIRNLSFDSEEEELGELLQQFGELKYVRIVLHPDTEHSKGCAFAQFMTQEAAQKCLLAASPE---------NEAGGLKLDGRQLKVDLAVTRDEAAKLQTTKVKK--------PTG--TRNLYLAREGLIRAGTKAAEGVSAADMAKRERFELLKHQKLK-DQNIFVSRTRLCLHNLPKAVDDKQLRKLLLSATSGEKGVRIKECRVMRDLKGVHGNMKGQSLGYAFAEFQEHEHALKALRLINNNPEIFGPLKRPIVEFSLEDRRKLKMKELRIQRSLQKMRSKPATGEPQKGQPEPAKD-QQQKAAQHHTEEQSKVPPEQKRKAGSTSWTGFQTKAEVEQVELPDGKKRRKVLALPSHRGPKIRLRDKGKVKPVHPKKPKPQINQWKQEKQQ-LSSEQVSRKKAKG------NKTETRFNQLVEQYKQKLLGPSKGAPLAK-------RSKWFDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W124-1", "uniprot_id": "Q9W124_DROME", "id": "Q9W124-1", "name": "RRM domain-containing protein", "aln": "------------------------------------------------------------------------------------MELKKMKSLKDDAAESQSQPETGVRKRRNPFNTQRLKEE----KERRQKK------------RARLIVRNISYKSTE-DSLREHFGQWGTLEDVHILKRGDGKLVGCAFVQYETINQATKAILNSNGKELLGRKVFVDWALGKDEYVSKNPK----DEEPDEKKPKVEVKEENGDEKEVKEESDAEVGKEDES-------------------------------------SGEDSDAESGEDEEDSGESEDEENDEDHKENKDELKSKLDIKNVKREKQISNDVQEGCTVFIKNVPFDAEDADLRKACRKFGLVSYAIINRQAVSGHSKGTAFVKFKAKESADLCLQAG---------------TEFKLMDEVLDPHPALSREEMKSKQSQENKK--------DDAKDSRNLYLAREGLIMAGAKAADGVSASDMAKRHELEQVKTQVLK-NLNRFVSRNRLSIHNLPQNYDNEKLKQMALTYTG----FRPHECRVMREHKVTPEHPQGKSKGFGFLSFDTHQRALAALRKLNNNPNIFGTQSRPIVAFSIEDRAVHKIKEKRTERSKQNNPTYQNKQQERKERRQQKRNGQETKTPVPQADNKSKLQKHIKKLEASRAAKAEGKVAEKKQLSDVQG----DFVGTAAKPGTSLKMRSKKKIVEQAKEHLKKVKTEKRKQKNKKIRESHLAERKANNRPKQGRKKETDDLRPLINKYKNMISGNQGGGGVTGGKIKKPKRTKWYTE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P37838-1", "uniprot_id": "NOP4_YEAST", "id": "P37838-1", "name": "Nucleolar protein 4", "aln": "MEETIENVEVPSSNVSKQNDDGLDMKTLFVRSIPQDVTDEQLADFFSNFAPIKHAVVVKDTN-KRSRGFGFVSFAVEDDTKEALAKARKTKFNGHILRVDIAKRRDRSKKTSEVVEKSTPESSEKITGQNNEDEDDADGEDSMLKGKPKLIIRNMPWSCRDPVKLKKIFGRYGTVVEATIPRKRDGKLCGFAFVTMKKISNCRIALENTKDLKIDGRKVAVDFAVQKNRWEDYKKAQPEMNDKDDNESGNEDAEENHDDEEDENEEEDRQVDQASKN---------------------------------------------------------------------------------KESKRKAQNKREDFSVFVRNVPYDATEESLAPHFSKFGSVKYALPVIDKSTGLAKGTAFVAFKDQYTYNECIKNAPAAGSTSLLIGDDVMPEYVYEGRVLSITPTLVREDAGRMAEKNAAKRKEALGKAPGEKDRRNLYLLNEGRVVEGSKMADLLTNTDMEIREKSYKLRVEQLKKNPSLHLSMTRLAIRNLPRAMNDKALKALAR----------KAVVEFATEVKNKERHPLSKE---------------EIIRSTKEKYKFMGPDE--IEAQKKKDKKSGVVKQAKVIMEVKGSTAGRSRGYGFVEFRDHKNALMGLRWLNCHAVTSDEILEGLNDDEKKQVDNDLGKGRRLCVEFAIEN------SNVVKRRREQLKQARTKRTRPDNEDTGDVGESENKKPKKEEATTPTNPDDKKMG----------DDIKRIIGFKRKRKHAKK---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : . :: : : . :.. . .: :.:**:**:.:.. : .*: * ::*:: :. * :: ***: * .*: :.: :. *: . : :: **.* **:*: *:.: . : .: : . : . ::. *:: ::..: . ... *..:: ..: *. :**::*:.:*: : * :** :.*. . : :** **. * : : : *: . .. *. :: *:: : * ***** .** : *:* *: :: :** *.. :: : ** : . .:* .**.::***: ::: *: : .. : * : .:. :* ::: : :*. . * . :*: :*: : . : : : . : : ..: . . . :. : .:: : . : :: *:: . * :. :: :: . . ", "identical_positions": 71, "similar_positions": 196, "identity": "8.54%" }, { "cls_id": "homologset.agr.SGD:S000005966", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920Q4-1", "uniprot_id": "VPS16_MOUSE", "id": "Q920Q4-1", "name": "Vacuolar protein sorting-associated protein 16 homolog", "aln": "--MDCYTANWNPLGDSAFYRKYELYSMDWDLKEELKDCLVAAAPYGGPIALLRNCWRKEKAAS-VRPVLEIYSASGLPLASLLWK--SGPVVALGWSAEEELLCVQEDGAVLVYGLHGDFRRHFSMGNEVLQNRVLDAR-IFHTEFGSGVAILTGAYRFTLSANVGDLKLRRMPEVPGLQSAPSCWTTLCHDRVPHILLAVG-PDLYLLDHATCSAVTPAGLAPGVSSFLQMAVSFTYRYLALFTDTGYIWMGTASLKEKLCEFNCNIRAPPKQMVWCSRP-RSKERAVVVAWERRLMVVGNAPESIQFVLDE-DSYLVPELDGVRIFSRSTHEFLHEVPVASEEIFKIASMAPGALLLEAQKEYEKESQKADEYLREIQELGQLIQAVQQCIEAAGHEHQPDMQKSLLRAASFGKCFLDRFPPDS--FVHMCQDLRVLNAIRDYHIGIPLTYTQYKQLTIQVLLDRLVLRRLYPLAIQICEYLRLPEVQGVSRILAHWACYKARAW-DMRDEDVARAINQKLG---DTPGVSYSDIAARAYGCGRTELAIKLLEYEPRSGEQVPLLLKMKRSKLALSKAIESGDTDLVFTVLLHLKNELNRGDFFMTLRNQPMALSLYRQFCKHQELDTLKDLYNQDDNHQELGSFHIRASYAAEERIEGRVAALQTAADAFYKAKNEFAAKATEDQMR----LLRIQRRLEDELGGRFLDLSLHDTVTTLILGGHNKRAEQLARDFRIPDKRLWWLKLAALADLEDWEELEKFSKSKKSPIGYLPFVEICMKQHNKHEAKKYASRVG---PEQKVKALLLVGDVAQAAEVAIEHRNETELSLVLSHCTGATDGAIADKIQRARAQAQKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H269-1", "uniprot_id": "VPS16_HUMAN", "id": "Q9H269-1", "name": "Vacuolar protein sorting-associated protein 16 homolog", "aln": "--MDCYTANWNPLGDSAFYRKYELYSMDWDLKEELRDCLVAAAPYGGPIALLRNPWRKEKAAS-VRPVLDIYSASGMPLASLLWK--SGPVVSLGWSAEEELLCVQEDGAVLVYGLHGDFRRHFSMGNEVLQNRVLDAR-IFHTEFGSGVAILTGAHRFTLSANVGDLKLRRMPEVPGLQSAPSCWTVLCQDRVAHILLAVG-PDLYLLDHAACSAVTPPGLAPGVSSFLQMAVSFTYRHLALFTDTGYIWMGTASLKEKLCEFNCNIRAPPKQMVWCSRP-RSKERAVVVAWERRLMVVGDAPESIQFVLDE-DSYLVPELDGVRIFSRSTHEFLHEVPAASEEIFKIASMAPGALLLEAQKEYEKESQKADEYLREIQELGQLTQAVQQCIEAAGHEHQPDMQKSLLRAASFGKCFLDRFPPDS--FVHMCQDLRVLNAVRDYHIGIPLTYSQYKQLTIQVLLDRLVLRRLYPLAIQICEYLRLPEVQGVSRILAHWACYKVQQK-DVSDEDVARAINQKLG---DTPGVSYSDIAARAYGCGRTELAIKLLEYEPRSGEQVPLLLKMKRSKLALSKAIESGDTDLVFTVLLHLKNELNRGDFFMTLRNQPMALSLYRQFCKHQELETLKDLYNQDDNHQELGSFHIRASYAAEERIEGRVAALQTAADAFYKAKNEFAAKATEDQMR----LLRLQRRLEDELGGQFLDLSLHDTVTTLILGGHNKRAEQLARDFRIPDKRLWWLKLTALADLEDWEELEKFSKSKKSPIGYLPFVEICMKQHNKYEAKKYASRVG---PEQKVKALLLVGDVAQAADVAIEHRNEAELSLVLSHCTGATDGATADKIQRARAQAQKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHG1-1", "uniprot_id": "VPS16_DROME", "id": "Q9VHG1-1", "name": "Vacuolar protein sorting-associated protein 16 homolog", "aln": "MPIMYNTGEWFKVRP-DYYRKVELATPDWPLDLDLEYMWVEVAPYGGPLAVTRDPTKLVPVKGNARPMIRIFDTTGREMGHILWN--HGKLIAMGWSDMEELICIQENATVFVYDMFGREKESYSIGDEASVTKIVEGK-VFQSSAGTGVAVMTTSGRVFLKQNS-SKTERKLPDIPNSSMNCSCWEIVTEGRNSYCLLGRDREVIKLFPGETVGTITANLFEKPHERIIKISVSYNHQHLALYTNTGLLWLGSVDMRQKYCEFDTGRKDMPLQMEWIMNSDNSEADAVVISYPSYLLIVNRNADRSDFPYDP-VMFLVAEMDGVRIITQSSHEIIQRLPKCVENIFAVNSQEPASYLFEAQKKFEEKSYKSDEYLSMCREK--IDLAVSECIEAASYEFCPETQKSLLRTAYFGKGFIRNHNPDE--YMRIMRILRVLNTLRHERIAMPITFKQFSHLNTEVILSRLVFRKHYAIAIQVAKHLNLPES----WILEHWAYHKVMN--DPNDTEVARKITEKFKNP-SVEGISFCNIASKAHQAGRDDLAIKLLELESRASLHVPLLLKMRKFDRAVGSATQSGDTELITQVLLEMKMHMMLSNLHMTIRDHPLALNIYKKIMRESNRAGLYGIYNTEDDQKAIAEYHFQN----AIETEGLESNLSMIGNAYAQGRCTLEAELCADTSR----LIKLQKTLSTKYNVSLNGLSIHETIQELLLIGELKEAERIRSEFKVPDRRFWWLRILTLSSQHKWEELEKLAKSKKSPIGYDPFVEVCLKQDNVMEARKYIPRCR---DNRRVVWYMRANLFNEAIDSAFEQRDVHSLFELQKNQAIVNNGTLLSKVCDCIAMLEGK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03308-1", "uniprot_id": "VPS16_YEAST", "id": "Q03308-1", "name": "Vacuolar protein sorting-associated protein 16", "aln": "--MKNPSFDWERLKD-VFYRSRAIGELKWPTQYEEFKCALSLT----------------VIAVEIQDFIQVYNYFGQLLGKINLQRIHEDIIKFEFDKDEKLILVTKSSIKIVKGWSPLTIESVPLQDPTIDTIWDYHNGIMLLAKSRDIYKLNGNEWELLYENK--DKKYNLLTKNHWSCNDDSIILLDVDHVYQVSTSNG-ALLKLITDSSWHKVTIS------SRGFICLYNMKDNKLQIFRDPARILM------------EHNLDSTPDDICWCGND------TVACSFEDEIKLYGPDGLYVTFWYPFTVTNLRAEVDGLKVITTEKIYFLSRVQPQTSNIFRIGSTEPGAMLVDSFSLLEDHAPKAIEILKN----FVLEKGVLDCIAAAIDEFEPKLQKMLLNAASYGKASLQYKSFDASIFVNACNTIKLLNCFR--SFGIFLTVEEYRCISLKGVIDRLLKYHRYYECIQICKLANERFLLG--YVFTEWAKDKIKGSPDMEDDELLDKIKSRLSVIDMTDTLQMVAVAKVAYLEGRFQLSRNLALLEKNEEARIEQLYNLDDDSIALKECIKVQNYSLTISLLIALSKKLTNSQLTKLLIIDMFNNPLYLYYMR-MDKAYLYDFYRQTDRFIDLAHVLLQQ----GKEQQSLHSFLPQIKDLYSQVQNSEVVNNTIEQLQRQEKLWIYQESLGKRFAISFTNMTLDQTLSKLIETGQDKQVKEIVKKFKISEKKLYHLKCKTLVEAKKFDELLQFAQSRKSPIGYMPFYTYLKSRGHMDKASPYVNMIPGLSYQEKKKLYVECRGFRDAIQLAGKEKDIPGLKEIYN-IIPPNEPELKALANETMSRI---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :* : :**. : .* . : : : : .: ::. * :. : : :: : :. *:*: : :.. :* . . .: : . . . :: . .: :. * * . .: . .. : .: . . : *: : :* . : . . . * :: :.. : : : . * :: * . :*. :: : : . * * .*:**::::: .. :: .: .:** : * *.: *.:: . *..: *: * * : .* :** ** *. *. ** **.:* :** : * ::. . :::** .* :.: :* :: :. : ::.**: : * .**:.: . :: .** * * * :: *..:: . :. :* *: ** :*: :* * . :: * :: . *: .. : : .* :*: :. .: .:: : . : :* : : * .:*. * :. :: . :. : * : : : : .: : : * *. * . : .:::.:*: *: *. *..:.: .*::.::::: *: :* . ..::** ::::*:****** ** .: : :* * :.: : . :* : * :.:: * : . .: : ", "identical_positions": 102, "similar_positions": 271, "identity": "11.85%" }, { "cls_id": "homologset.agr.SGD:S000005967", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P83941-1", "uniprot_id": "ELOC_RAT", "id": "P83941-1", "name": "Elongin-C", "aln": "MDGEEKTYGGCEGPDAMYVKLISSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEVNFREIPSHVLSKVCMYFTYKVRYT---NSSTEIPEFPIAPEIALELLMAANFLDC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0M532-1", "uniprot_id": "A0ABK0M532_RAT", "id": "A0ABK0M532-1", "name": "Elongin-C", "aln": "MDGEEKTYGGCEGPDAMYVKLISSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEVNFREIPSHVLSKVCMNFTYKVRYT---NSSTEIPEFPTAPEIALELLMAVNFLDC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15369-1", "uniprot_id": "ELOC_HUMAN", "id": "Q15369-1", "name": "Elongin-C", "aln": "MDGEEKTYGGCEGPDAMYVKLISSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEVNFREIPSHVLSKVCMYFTYKVRYT---NSSTEIPEFPIAPEIALELLMAANFLDC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P83940-1", "uniprot_id": "ELOC_MOUSE", "id": "P83940-1", "name": "Elongin-C", "aln": "MDGEEKTYGGCEGPDAMYVKLISSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEVNFREIPSHVLSKVCMYFTYKVRYT---NSSTEIPEFPIAPEIALELLMAANFLDC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03071-1", "uniprot_id": "ELOC_YEAST", "id": "Q03071-1", "name": "Elongin-C", "aln": "MSQD-------------FVTLVSKDDKEYEISRSAAMISPTLKAMIEGP--FRESKG-RIELKQFDSHILEKAVEYLNYNLKYSGVSEDDDEIPEFEIPTEMSLELLLAADYLSI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : :*.*:*.*.:*: :.*. *: * *:***:.** * *.: .:::::: **:*.*. :.*:::*: :.. ***** ..*::****:*.::*. ", "identical_positions": 35, "similar_positions": 46, "identity": "30.43%" }, { "cls_id": "homologset.agr.SGD:S000005968", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M2B264-1", "uniprot_id": "A0A8M2B264_DANRE", "id": "A0A8M2B264-1", "name": "Ataxin-7-like protein 3", "aln": "MKMEDVSLSSMDNSKMEGFAQEILSDLVEDACLGLCFEVHRAVKQGYFFLDDTDQESMKDFEIVDQPGVDIFGQVYNQWKNKECVCPNCSRSIAASRFAPHLEKCLGMGRNSSRIANRRIASGNNTNKSESDQEDNDDVNDNDWSYGAEKKAKKRKSDK----------------------------------------------------------------------------------VFLHS------------LKQPVHLNPN----------------SPRRSKSMKHKN---------------------GRLNRRDEPEKISTS--KKAESQNTPLITTGQW-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1L209-1", "uniprot_id": "AT7L3_DANRE", "id": "A1L209-1", "name": "Ataxin-7-like protein 3", "aln": "MKMEDMSLSGLDNTKLEALAHDVYSDLVEDACLGLCFEVHRAVKQGYFFLDETDQESMKDFEIVDQPGVDIFGQVYNQWKNKECVCPNCSRSIAASRFAPHLEKCLGMGRNSSRIANRRIASSNNTSKSESDQEDNDDINDNDWSYGSEKKAKKRKSEKNPNSPRRSKSLKHKNGELSGSVNPDMYKYNYSSGISYETLGPEELRSILTTQCGVVSEHTKKMCTRSQRCPQHTDEQRRAVRVFLLGPSASTLPDADTMLENEAYEPPDGQLIMSRLHWDASSDISPSDSASSKASTNNSESKRPKKKKPSTLSLTPAGERDKAQERDRIAGSGSSGSSSQNALGLSSRKKRPKLAVPPAPSIYDDLN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03067-1", "uniprot_id": "SGF11_YEAST", "id": "Q03067-1", "name": "SAGA complex subunit SGF11", "aln": "MTEETITIDSISNGILNNLLTTLIQDIVARETTQQQLLKTRYPDLRSYYFDPNGSLDINGLQKQQES---------SQYIH----CENCGRDVSANRLAAHLQRCLSRG-------ARR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. * :::..:.* :: : : .*:* : * . :::* ... .::.:: ::. .*: : * **.*.::*.*:*.**::**. * ** ", "identical_positions": 22, "similar_positions": 44, "identity": "5.99%" }, { "cls_id": "homologset.agr.SGD:S000005969", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68FR6-1", "uniprot_id": "EF1G_RAT", "id": "Q68FR6-1", "name": "Elongation factor 1-gamma", "aln": "MAAGTLYTYPENWRAFKALIAAQYSGAQIRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDDGFCVFESNAIAYYVS---------NEELRG-STPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVKRILGLLDTHLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAILGEVKLCEKMAQFDAKKFAESQPKKDTPRK-EKGSREE-KQKPQ----TERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLPKSTFVLDEFKRKYSNEDTLSVALPYFWEHFDKDGWSLWYAEYRFPEELTQTFMSCNLITGMFQRLDKLRKNAFASVILFGTNNSSSISGVWVFRGQDLAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWEG--AFQHVGKAVNQGKIFK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D8N0-1", "uniprot_id": "EF1G_MOUSE", "id": "Q9D8N0-1", "name": "Elongation factor 1-gamma", "aln": "MAAGTLYTYPENWRAFKALIAAQYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDDGFCVFESNAIAYYVS---------NEELRG-STPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVKRILGLLDTHLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAILGEVKLCEKMAQFDAKKFAESQPKKDTPRK-EKGSREE-KQKPQ----AERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLPKSTFVLDEFKRKYSNEDTLSVALPYFWEHFDKDGWSLWYAEYRFPEELTQTFMSCNLITGMFQRLDKLRKNAFASVILFGTNNSSSISGVWVFRGQELAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWEG--TFQHVGKAVNQGKIFK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P26641-1", "uniprot_id": "EF1G_HUMAN", "id": "P26641-1", "name": "Elongation factor 1-gamma", "aln": "MAAGTLYTYPENWRAFKALIAAQYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDDGFCVFESNAIAYYVS---------NEELRG-STPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVRRILGLLDAYLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAVLGEVKLCEKMAQFDAKKFAETQPKKDTPRK-EKGSREE-KQKPQ----AERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLPKSTFVLDEFKRKYSNEDTLSVALPYFWEHFDKDGWSLWYSEYRFPEELTQTFMSCNLITGMFQRLDKLRKNAFASVILFGTNNSSSISGVWVFRGQELAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWEG--AFQHVGKAFNQGKIFK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PE25-1", "uniprot_id": "EF1G_DANRE", "id": "Q6PE25-1", "name": "Elongation factor 1-gamma", "aln": "MAAGTLYTYPENWRAFKAQIAAQYSGARLKIASAPPAFTFGQTNRSPAFLGNFPLGKVPAYQGDDGFCLFESNAIAHYLS---------NDVLRG-STPQASAQVLQWVSFADSEVIPPASAWVFPTLGIMQFNKQATEQAKEEVKRVLAVLNQHLNTRTFLVGERISLADITVVCSLLWLYKQVLEPAFRQPYPNVTRWFVTCVNQPQFKTVLGEVKLCEKMAQFDAKKFAEMQPKKEAPIKKEKGGKEGGKQQPQQQEKKEKKKEEKKAAPA-EEEMDECEAALASEPKAKDPFAHLPKSSFVMDEFKRKYSNEDTMTVALPYFWDHFDREGFSIWYAEYRFPEELTMAFMSCNLITGMFQRLDKLRKNAFASVILFGANNDSCISGIWVFRGQDLAFPLSDDWQIDYESYTWRKLDVDSEECKTMVKEYFAWEG--EFKHVGKPFNQGKIFK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NJH0-1", "uniprot_id": "EF1G_DROME", "id": "Q9NJH0-1", "name": "Elongation factor 1-gamma", "aln": "MVKGTLYTYPENFRAYKALIAAQYSGAQVKVADN---FKFGETNKSAEFLKKFPGGKVPAFETAEGQYLSESNAIAYLLA---------NEQLRGGKCPFVQAQVQQWISFADNEIVPASCAWVFPLLGILPQQKNS--TAKQEAEAVLQQLNQKLQDATFLAGERITLADIVVFSSLLHLYEYVLEPSVRSAFGNVNRWFVTILNQKQVQAVVKDYKLCEKALVFDPKKYAEFQAKTGAAKPQQQAQQQKQEKKPK-----EKKEAPKKAAEP-AEELDAADEALAAEPKSKDPFDALPKGTFNFDDFKRVYSNED-EAKSIPYFFDKFDAENYSIWFGEYKYNEELSKVFMSCNLITGMFQRLDKMRKAAFASVCLFGEDGNSTISGIWVWRGQDLAFTLSPDWQIDYEVYDWKKLDAKSEETKKLVTQYFSWSG--TDKD-GRKFNQGKIFK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P29547-1", "uniprot_id": "EF1G1_YEAST", "id": "P29547-1", "name": "Elongation factor 1-gamma 1", "aln": "MSQGTLYANFR-IRTWVPRGLVKALKLDVKVVTP--------DAAAEQFARDFPLKKVPAFVGPKGYKLTEAMAINYYLVKLSQDDKMKTQLLGADDDLNAQAQIIRWQSLANSDLCIQIANTIVPLKGGAPYNKKSVDSAMDAVDKIVDIFENRLKNYTYLATENISLADLVAASIFTRYFESLFGTEWRAQHPAIVRWFNTVRASPFLKDEYKDFKFADKPLSPPQKKKEKKAP-----------------------------AAAPAASKKKEEAKPAATETETSSKKPKHPLELLGKSTFVLDDWKRKYSNEDTRPVALPWFWEHYNPEEYSLWKVTYKYNDELTLTFMSNNLVGGFFNRLSASTKYMFGCLVVYGENNNNGIVGAVMVRGQ--DYVPAFDVAPDWESYDYAKLDPTNDDDKEFINNMWAWDKPVSVNGEPKEIVDGKVLK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ****: . *:: . .: ::: : * .** ****: .* : *: ** : : .: * . . . **: :* *:*:.:: . :.* * :*:: * : . :: :: *: *:*. *.::***:.. . : :: :: . * . *** * . .: : *:.:* ** : . *: * . : ::. *.*.*: * *.:* :*::** ***** . ::*:*::::: : :*:* *:: :**: .*** **: *:*:**. * *..: ::* :... * * : *** : : * *:* * : *** .:: : :: : ::*. : : . :**::*", "identical_positions": 94, "similar_positions": 133, "identity": "20.66%" }, { "cls_id": "homologset.agr.SGD:S000005972", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63055-1", "uniprot_id": "ARFRP_RAT", "id": "Q63055-1", "name": "ADP-ribosylation factor-related protein 1", "aln": "MYTLLSGLYKYMFQKDEYCILILGLDNAGKTTFLEQSKTRFNKNYKGMSLSKITTTVGLNIGTVDVG-KARLMFWDLGGQEELQSLWDKYYAECHGVIYVIDSTDEERLSESKEAFEKVVSSEALDGVPILVLANKQDVETCLSIPDIKTAFSDCTCKIGRRDCLTQACSALTGKGVREGIEWMVKCVVRN-VHRPPRQRDIT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BXL7-1", "uniprot_id": "ARFRP_MOUSE", "id": "Q8BXL7-1", "name": "ADP-ribosylation factor-related protein 1", "aln": "MYTLLSGLYKYMFQKDEYCILILGLDNAGKTTFLEQSKTRFNKNYKGMSLSKITTTVGLNIGTVDVG-KARLMFWDLGGQEELQSLWDKYYAECHGVIYVIDSTDEERLSESKEAFEKVVSSEALDGVPILVLANKQDVETCLSIPDIKTAFSDCTCKIGRRDCLTQACSALTGKGVREGIEWMVKCVVRN-VHRPPRQRDIT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13795-1", "uniprot_id": "ARFRP_HUMAN", "id": "Q13795-1", "name": "ADP-ribosylation factor-related protein 1", "aln": "MYTLLSGLYKYMFQKDEYCILILGLDNAGKTTFLEQSKTRFNKNYKGMSLSKITTTVGLNIGTVDVG-KARLMFWDLGGQEELQSLWDKYYAECHGVIYVIDSTDEERLAESKQAFEKVVTSEALCGVPVLVLANKQDVETCLSIPDIKTAFSDCTSKIGRRDCLTQACSALTGKGVREGIEWMVKCVVRN-VHRPPRQRDIT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W389-1", "uniprot_id": "Q9W389_DROME", "id": "Q9W389-1", "name": "ADP-ribosylation factor-related protein 1", "aln": "MYTLMHGFYKYMTQKDDYCVVILGLDNAGKTTYLEAAKTTFTRNYKGLNPSKITTTVGLNIGTIDVQ-GVRLNFWDLGGQQELQSLWDKYYQESHGVIYVIDSNDRERMEESKAIFDKMIKNELLSGVPLLILANKQDLPDVMGVREIKPVFQQAGALIGRRDCLTIPVSALHGEGVDEGIKWLVEAIKRHAVVRPPREND--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02804-1", "uniprot_id": "ARL3_YEAST", "id": "Q02804-1", "name": "ADP-ribosylation factor-like protein 3", "aln": "MFHLVKGLYNNWNKKEQYSILILGLDNAGKTTFLETLKKEYSLAFK--ALEKIQPTVGQNVATIPVDSKQILKFWDVGGQESLRSMWSEYYSLCHGIIFIVDSSDRERLDECSTTLQSVVMDEEIEGVPILMLANKQDRQDRMEVQDIKEVFNKIAEHISARDSRVLPISALTGEGVKDAIEWMIVRLERNKKSRPPIYK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *: *:*: :*::*.::***********:** *. :. :* .** .*** *:.*: * * ***:***:.*:*:*.:** .**:*:::**.*.**: *.. ::.:: .* : ***:*:****** : : :** .*.. *. **. . . *** *:** :.*:*:: : *: *** . ", "identical_positions": 79, "similar_positions": 65, "identity": "38.92%" }, { "cls_id": "homologset.agr.SGD:S000005975", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXP6-1", "uniprot_id": "MKRN1_MOUSE", "id": "Q9QXP6-1", "name": "E3 ubiquitin-protein ligase makorin-1", "aln": "MAEAAAPGTTATTSGAGAAAAAVA----AASLTSIPTVAAPSPGAGGGGGGSDGSGGG-------------------------------WTKQVTCRYFMHGVCKEGDNCRYSHDLSDSPYGVVCKYFQRGYCVYGDRCRYEHSKPLKQEEVTATDLSAKPSLAASSSLSSGVGSLAEMNSGEAESRNPSFPTVGAGSEDWVNAIEFVPGQPYCGRTAPSCTEVPPQGSVTKEESEKEPTTVETKKQLCPYAAVGECRYGENCVYLHGDSCDMCGLQVLHPVDAAQRSQHIKSCIEAHEKDMELSFAVQRTKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLIQKYKEAMSNKACRYFDEGRGSCPFGGNCFYKHAYPDGRREEPQ--RQKVGTSSRYRAQRRSHFWELIEEREN-NPFDNDEEEVVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDFYDLDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHC7-1", "uniprot_id": "MKRN1_HUMAN", "id": "Q9UHC7-1", "name": "E3 ubiquitin-protein ligase makorin-1", "aln": "MAEAATPGTTATTSGAGAAAATAA----AASPTPIPTVTAPSLGAGGGGGGSDGSGGG-------------------------------WTKQVTCRYFMHGVCKEGDNCRYSHDLSDSPYSVVCKYFQRGYCIYGDRCRYEHSKPLKQEEATATELTTKSSLAASSSLSSIVGPLVEMNTGEAESRNSNFATVGAGSEDWVNAIEFVPGQPYCGRTAPSCTEAPLQGSVTKEESEKEQTAVETKKQLCPYAAVGECRYGENCVYLHGDSCDMCGLQVLHPMDAAQRSQHIKSCIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLILKYKEAMSNKACRYFDEGRGSCPFGGNCFYKHAYPDGRREEPQ--RQKVGTSSRYRAQRRNHFWELIEERENSNPFDNDEEEVVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDFYDLDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q13434-1", "uniprot_id": "MKRN4_HUMAN", "id": "Q13434-1", "name": "Putative E3 ubiquitin-protein ligase makorin-4", "aln": "MAEAAAPGTTVTTSGAGAAAAEAAETAEAVSPTPIPTVTAPSPRAGGGVGGSDGSDGSGGRGDSGAYDGSGACGGSDACDGSGDSSGDSWTKQVTCRYFKYGICKEGDNCRYSHDLSDRLCGVVCKYFQRGCCVYGDRCRCEHSKPLKQEEATATELTTKSSLAASSSLSSIVGPLVEMNTNEAESRNSNFATVVAGSEDWANAIEFVPGQPYCGRTVPSCTEAPLQGSVTKEESEEEQTAVETKKQLCPYAAVGQCRYGENCVYLHGDLCDMCGLQVLHPMDAAQRSQHIQACIEAHEKDMEFSFAVQRSKDKVCGICMEVVYEKANPNEHRFGILSNCNHTFCLKCIRKWRSAKEFESRIVKSCPQCRITSNFVIPSEYWVEEKEEKQKLIQKYKEAMSNKACKYFDEGRGSCPFGENCFYKHMYPDGRREEPQ--RQQVGTSSRNPGQQRNHFWEFFEEGANSNPFD-DEEEAVTFELGEMLLML-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4VBT5-1", "uniprot_id": "MKRN1_DANRE", "id": "Q4VBT5-1", "name": "Probable E3 ubiquitin-protein ligase makorin-1", "aln": "MAEAAAASTAAPAVIGG------------------------------------------------------------------------WTKHVTCRYFMHGLCKEGENCRYSHDLSSCKQTMICKFFQKGCCAFGDRCRYEHTKPSKQDEVPS----SKPSMPLTAAP--LAGTPEPVSDGPGGTTGAQEKPQGSGAVDWVNAAEFVPGQPYCGRADPVLCEGP--GPLIEEEYEKEQANKEMKKQLCPYAAVGECRYGLNCAYLHGDVCDMCGLQVLHPSDTSQRSQHIRACIEAHEKDMEISFAIQRSKDMMCGVCMEVVFEKTNPSERRFGILSNCCHCYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEDKEEKQQLIQKYKDGMGTKPCRYFDEGRGTCPFGANCFYKHAFPDGRLEEPQPQRRQNGSNGRNRNTRRTHLWDLLDERENSDSFDNEDEEMVRFELSEMLLMLLAAGTDDDVTDSEDEWDLFHEELDDYYELYL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02799-1", "uniprot_id": "LEE1_YEAST", "id": "Q02799-1", "name": "Zinc finger protein LEE1", "aln": "---------------------------------------------------------------------------------------------MDAFENMSVSNHPGGNARRNSQSANEMLASQIQDFQN--------------------------------------------IPRSFNDSNANVNLSKNCTVGN-------------QLPFSSRQQKIIMEHLL---ITKNNSQQQ---KDYSHVPCKFFKMGNCQAGSSCPFSHSPDIISSANNLPCKYFAKGNCKFGNKCVNAHVLPNGFKMNSKEPIDITP------------PSQNNY-LSHARSASFSTYTSPPLSAQTEFSHSASNAN---------YFSSQYLMYSPQKSPEALYTEFFSPPSSSSSYINYSYNNSNINAYSPVSSSSSNIWQEQGQ---TTLSNPSVNQNLRYRTGPAIQEESDN--------------EIEDLLIHNFNSRYCHE-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : * *.* . : :. : **. .. . . .. . *:..* * : ::: ::: : .: * : :*:*: * .* : *. .. :: : ..:. . *::** :.: :.. * *.:..: : :. : .:*. :: :.*:* : . ::. : : . . .... *:: . ... :. . . .: *: * .. . : : :* * *: ::*: ", "identical_positions": 29, "similar_positions": 108, "identity": "5.59%" }, { "cls_id": "homologset.agr.SGD:S000005980", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADD7-1", "uniprot_id": "D4ADD7_RAT", "id": "D4ADD7-1", "name": "Glutaredoxin-related protein 5, mitochondrial", "aln": "MRLPGKAHRYGVSDMIGGIEPVLSNHETHPRAYPMRTSSGPAGHQGLCKPSGGRRSGDQRAGMSASLSRAAAALLRWGRGAGGGVLPRAGVRAASS----GGQAEQLDALVKKDKVVVFLKGTPEQPQCGFSNAVVQILRLHGVR--DYAAYNVLEDPELRQGIKDYSNWPTIPQVYLNGEFVGGCDILLQMHQNGDLVEELKKLGIRSALIDEK-DQDSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80Y14-1", "uniprot_id": "GLRX5_MOUSE", "id": "Q80Y14-1", "name": "Glutaredoxin-related protein 5, mitochondrial", "aln": "--------------------------------------------------------------MSASLSRAAAALLRWGRSAGGGGLPGAGVRAASS----GGQAEQLDALVKKDKVVVFLKGTPEQPQCGFSNAVVQILRLHGVR--DYAAYNVLDDPELRQGIKDYSNWPTIPQVYLNGEFVGGCDILLQMHQNGDLVEELKKLGIRSALVDEK-DQDSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86SX6-1", "uniprot_id": "GLRX5_HUMAN", "id": "Q86SX6-1", "name": "Glutaredoxin-related protein 5, mitochondrial", "aln": "--------------------------------------------------------------MSGSLGRAAAALLRWGRGAGGGGLWGPGVRAAGSGAGGGGSAEQLDALVKKDKVVVFLKGTPEQPQCGFSNAVVQILRLHGVR--DYAAYNVLDDPELRQGIKDYSNWPTIPQVYLNGEFVGGCDILLQMHQNGDLVEELKKLGIHSALLDEKKDQDSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PBM1-1", "uniprot_id": "GLRX5_DANRE", "id": "Q6PBM1-1", "name": "Glutaredoxin-related protein 5, mitochondrial", "aln": "----------------------------------------------------------MNSVFRSTARCLRSATWQYKTAHKNGELSVGRARLMCS----SAGQKNLEEMVKKDKVVVFMKGTPAQPMCGFSNAVVQILRMHGVD--NYASYNVLDDQDVRQGIKTFSNWPTIPQVFFNGEFVGGCDILLQMHQSGDLVEELQKLGIRSALLDQE--KESK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02784-1", "uniprot_id": "GLRX5_YEAST", "id": "Q02784-1", "name": "Monothiol glutaredoxin-5, mitochondrial", "aln": "-----------------------------------------------------------------MFLPKFNPIRSFSPILRAKTLLRYQNRMYLS----TEIRKAIEDAIESAPVVLFMKGTPEFPKCGFSRATIGLLGNQGVDPAKFAAYNVLEDPELREGIKEFSEWPTIPQLYVNKEFIGGCDVITSMARSGELADLLEEAQALVPEEEEE-TKDR-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * * * : :: ::. **:*:**** * ****.*.: :* :** .:*:****:* ::*:*** :*:******::.* **:****:: .* :.*:*.: *:: . ::: :: ", "identical_positions": 47, "similar_positions": 44, "identity": "21.27%" }, { "cls_id": "homologset.agr.SGD:S000005981", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ET09-1", "uniprot_id": "MRS2_RAT", "id": "Q9ET09-1", "name": "Magnesium transporter MRS2 homolog, mitochondrial", "aln": "MECLRYLPRLLPRAAQ-SRSALCMAAVRLS-----LAACCGRATPLT-SGSQK--APSTPRTAGDVYRFRTSDASQATLASVAQVFAVTKFDKEGNVTS--FERKKTELYHELALQARDLR-------FQHVMSITTRNNRIIMRMEYLKAVITPEYLLILDYR------NLNLEHWLFRELPSQLAGE--GQLVTYPLPFEFRAIEALLQYWINTLQGKLSILQPLILETLDALVDPKHSSVDRSKLHVLLQNGKSLSELETDIKIFKESILELLDEEEMLEELCLTKWSDPHVFEQSSTGIDHAEEMELLLENYYRLADDLSNEARELRVLIDDSQSIIFINLDSHRNVMMRLNLQLTMGTFSLSLFGLMGVAFGMNLESSLEEDHRVFWLITGIMFMGSGLIWRRLLSFLGRQLEAPLPPVMASLPKKTLLADRRMDVKNSLRPEGLGAGRTILASR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5NCE8-1", "uniprot_id": "MRS2_MOUSE", "id": "Q5NCE8-1", "name": "Magnesium transporter MRS2 homolog, mitochondrial", "aln": "MECLRCLPGLLPRAAQ-PRRALWTAVARLS-----LAACGGRATPLR-SRSPK--ASSTARAAGDVLRFRTSDASQATLASVAQVFAVTKFDKEGNVTS--FERKKTELYHELALQARDLR-------FQHVMSITTRNNRIIMRMEYLKAVITPECLLILDYR------NLNLEHWLFRELPSQLAGE--GQLVTYPLPFEFRAIEALLQYWISTLRGRLSVLQPLILETLDALVDPKHSSVDRSKLHVLLQNGKSLSELETDIKIFKESILELLDEEEMLEELCLTKWSDPHVFEKSSTGIDHAEEMELLLENYYRLAEDLSNEARELRVLIDDSQSIIFINLDSHRNVMMRLNLQLTMGTFSLSLFGLMGVAFGMNLESSLEEDHRVFWLVTGIMFMGSGLIWRRLLSFLGRQLEAPVPPVMTSLPKKTLLANRRMDVKNSLRPEGLGASRTILASR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HD23-1", "uniprot_id": "MRS2_HUMAN", "id": "Q9HD23-1", "name": "Magnesium transporter MRS2 homolog, mitochondrial", "aln": "MECLRSLPCLLPRAMRLPRRTLCALALDVTSVGPPVAACGRRANLIGRSRAAQLCGPDRLRVAGEVHRFRTSDVSQATLASVAPVFTVTKFDKQGNVTS--FERKKTELYQELGLQARDLR-------FQHVMSITVRNNRIIMRMEYLKAVITPECLLILDYR------NLNLEQWLFRELPSQLSGE--GQLVTYPLPFEFRAIEALLQYWINTLQGKLSILQPLILETLDALVDPKHSSVDRSKLHILLQNGKSLSELETDIKIFKESILEILDEEELLEELCVSKWSDPQVFEKSSAGIDHAEEMELLLENYYRLADDLSNAARELRVLIDDSQSIIFINLDSHRNVMMRLNLQLTMGTFSLSLFGLMGVAFGMNLESSLEEDHRIFWLITGIMFMGSGLIWRRLLSFLGRQLEAPLPPMMASLPKKTLLADRSMELKNSLRLDGLGSGRSILTNR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02783-1", "uniprot_id": "LPE10_YEAST", "id": "Q02783-1", "name": "Mitochondrial inner membrane magnesium transporter MFM1", "aln": "---MRAFPRVLPFRHQRSYNNILLRTVRLF---------GSSLSSFDFSRQMP--KVDPDNTAAMLLQKNLIQRNNMLYGYGSGTIRCTLLDSTGRAKSPLVEIKREDLVSKHGLLPRDLRKIEKSRKNDLVPSLLVRENSILISLLTVKALIKPDMVIIFDSAGSGITLNSEAHKDFINDMKLRLKNQETSELNSDPLPYEFRALETIFISALSNLTSEMKVLLTICKG----VLQDLEFSITRDKLRFLLGQNKKLSSFNKKAVLVKDMLDDLLEQDDMLCDMYLTDKKAGKIRVQ-----DDHTEIEMLLETYHNYVDEIVQKSESAISDVKTTEEIINIILDSNRNELMLLGIRYAIGMLSLGGALFLGSIYGMNLESFIEESNYAYLTVTILGLISTVWLYAKGIRHLHKLQRMTLLSKIKTDSVHELLKK------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :* :** : . : . : . : * . ..*. : : . : .: . : .: * :*. *...* .* *: :* : .* .**** : * *: .*:* *:: : :**:*.*: ::*:* * : .: ::.:: :* .: .:* : ***:****:*::: :..* ..:.:* .: ::: . *: *.**:.** :.*.**.::.. :.*: : ::*:::::* :: ::. . :: : *. *:*:***.*:. .::: : :.. :. ::.** * ***:** :* *.:: ::* :**. ::* :****** :**.: : :* : ::.: :: : : .* : . .: . : : . : ** . ", "identical_positions": 87, "similar_positions": 170, "identity": "18.91%" }, { "cls_id": "homologset.agr.SGD:S000005982", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CZS1-1", "uniprot_id": "AL1B1_MOUSE", "id": "Q9CZS1-1", "name": "Aldehyde dehydrogenase family 1 member B1, mitochondrial", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLTARLLLPRLLCLQGR-TTSYSTAAALPNPIPNPEIC-----------------------------------------------------------------YNKLFINNEWHDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDLAVKAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYVLDLDEVIKVYRYFAGWADKWHGKTIPMDGE----HFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGHLIQKAAGESNLKRVTLELGGKSPSIVLADADMEHAVDQCHEALFFNMGQCCCAGSRTFVEESIYREFLERTVEKAKQRK-VGNPFELDTQQGPQVDKEQFERILGYIRLGQKEGAKLLCGGER-LGERGFFIKPTVFGDVQDGMRIAKEEIFGPVQPLFKFK--KIEEVIQRANNTRYGLAAAVFTRDLDKAIYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLRAYTEVKTVTIKVPEKNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66HF8-1", "uniprot_id": "AL1B1_RAT", "id": "Q66HF8-1", "name": "Aldehyde dehydrogenase family 1 member B1, mitochondrial", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLNARFLVPRLLCLQGR-TTSYSTAAALPNPIPNPEIR-----------------------------------------------------------------YNQLFINNEWHDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDLAVRAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYVLDLDEVIKVYRYLAGWADKWHGKTIPMDGE----HFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMDHAVDQCHEALFFNMGQCCCAGSRTFVEESIYHEFLERTVEKAKKRK-VGNPFELDTQQGPQVDKEQFEKILGYIRLGQKEGAKLLCGGER-FGERGFFIKPTVFGNVQDDMRIAREEIFGPVQPLFKFK--KIEEVIQRANNTRYGLAAAVFTRDLDKALYFSQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIKVSEKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30837-1", "uniprot_id": "AL1B1_HUMAN", "id": "P30837-1", "name": "Aldehyde dehydrogenase family 1 member B1, mitochondrial", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ML--RFLAPRLLSLQGR-TARYSSAAALPSPILNPDIP-----------------------------------------------------------------YNQLFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDRAVKAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYALDLDEVIKVYRYFAGWADKWHGKTIPMDGQ----HFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHVDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFLERTVEKAKQRK-VGNPFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGER-FGERGFFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFK--KIEEVVERANNTRYGLAAAVFTRDLDKAMYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIKVPQKNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47738-1", "uniprot_id": "ALDH2_MOUSE", "id": "P47738-1", "name": "Aldehyde dehydrogenase, mitochondrial", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRAALTTVRRGPRLSR-LLSAAATSAVPAPNHQPEVF-----------------------------------------------------------------CNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGNKEDVDKAVKAARAAFQLGSPWRRMDASDRGRLLYRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGD----FFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEGVDKVAFTGSTEVGHLIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQENVYDEFVERSVARAKSRV-VGNPFDSRTEQGPQVDETQFKKILGYIKSGQQEGAKLLCGGGA-AADRGYFIQPTVFGDVKDGMTIAKEEIFGPVMQILKFK--TIEEVVGRANDSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11884-1", "uniprot_id": "ALDH2_RAT", "id": "P11884-1", "name": "Aldehyde dehydrogenase, mitochondrial", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRAALSTARRGPRLSR-LLSAAATSAVPAPNQQPEVF-----------------------------------------------------------------CNQIFINNEWHDAVSKKTFPTVNPSTGEVICQVAEGNKEDVDKAVKAAQAAFQLGSPWRRMDASDRGRLLYRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGD----FFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEVGHLIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDVYDEFVERSVARAKSRV-VGNPFDSRTEQGPQVDETQFKKILGYIKSGQQEGAKLLCGGGA-AADRGYFIQPTVFGDVKDGMTIAKEEIFGPVMQILKFK--TIEEVVGRANNSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05091-1", "uniprot_id": "ALDH2_HUMAN", "id": "P05091-1", "name": "Aldehyde dehydrogenase, mitochondrial", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRAA---ARFGPRLGRRLLSAAATQAVPAPNQQPEVF-----------------------------------------------------------------CNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGD----FFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSRV-VGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGI-AADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFK--TIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLC5-1", "uniprot_id": "Q9VLC5_DROME", "id": "Q9VLC5-1", "name": "aldehyde dehydrogenase (NAD(+))", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRVLKTGALLRSQAKNFAAAVANYSSLPQPQTTPDIL-----------------------------------------------------------------YTGVFINNEWHKSKSGKIFETINPTTAEVIAEIQCADKEDIDIAVQAARNAFKLGSPWRRMDASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWADKNHGKTIPMDGD----FFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPAEQTSLTALYIAQLVKEAGFPEGVVNVVPGFG-TAGAALANHCDVDKVAFTGSTDVGKLIQLASGNTNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKKRT-VGNPFDLNTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGGSRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFK--KLDEVIERANNSEYGLAAAVFTKDLDKANYIVGGLRAGTVWVNTYNVLAAQAPFGGYKMSGHGRENGEYALSNYTEVKSVIVKVAQKNS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9JHW9-1", "uniprot_id": "AL1A3_MOUSE", "id": "Q9JHW9-1", "name": "Retinaldehyde dehydrogenase 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATTN------GAVENG--QPDGKPPALPRPIRNLEVK-----------------------------------------------------------------FTKIFINNDWHESKSGRKFATYNPSTLEKICEVEEGDKPDVDKAVEAAQAAFQRGSPWRRLDALSRGQLLHQLADLVERDRAILATLETMDTGKPFLHAFFVDLEGCIKTFRYFAGWADKIQGRTIPTDDN----VVCFTRHEPIGVCGAITPWNFPLLMLAWKLAPALCCGNTVVLKPAEQTPLTALYLASLIKEVGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVREAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYGEFVRRSVEFAKKRP-VGDPFDAKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSA-MEDRGLFIKPTVFSDVTDNMRIAKEEIFGPVQPILKFK--NLEEVIKRANSTDYGLTAAVFTKNLDKALKLAAALESGTVWINCYNAFYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLEEKNP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K4D8-1", "uniprot_id": "AL1A3_RAT", "id": "Q8K4D8-1", "name": "Retinaldehyde dehydrogenase 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATAN------GAVENG--QPDGKPPALPRPIRNLEVK-----------------------------------------------------------------FTKIFINNDWHEPKSGRKFATYNPSTLEKICEVEEGDKPDVDKAVEAAQAAFQRGSPWRRLDALSRGQLLHQLADLIERDRAILATLETMDTGKPFLHAFFVDLEGCIKTFRYFAGWADKIQGRTIPTDDN----VMCFTRHEPIGVCGAITPWNFPLLMLAWKLAPALCCGNTVVLKPAEQTPLTALYLASLIKEVGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGRNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYGEFVRRSVEFAKKRP-VGDPFDAKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSA-MEDRGLFIKPTVFSDVTDNMRIAKEEIFGPVQPILKFK--NLEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWVNCYNAFYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLDEKNP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47895-1", "uniprot_id": "AL1A3_HUMAN", "id": "P47895-1", "name": "Retinaldehyde dehydrogenase 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATAN------GAVENG--QPDRKPPALPRPIRNLEVK-----------------------------------------------------------------FTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDN----VVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRP-VGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSA-MEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFK--SIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGDKNP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P24549-1", "uniprot_id": "AL1A1_MOUSE", "id": "P24549-1", "name": "Aldehyde dehydrogenase 1A1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSS-------------------PAQPAVPAPLADLKIQ-----------------------------------------------------------------HTKIFINNEWHNSVSGKKFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLMERDRLLLATMEALNGGKVFANAYLSDLGGCIKALKYCAGWADKIHGQTIPSDGD----IFTYTRREPIGVCGQIIPWNFPMLMFIWKIGPALSCGNTVVVKPAEQTPLTALHLASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTQVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDIAVEFAHHGVFYHQGQCCVAASRIFVEESVYDEFVKRSVERAKKYV-LGNPLTPGINQGPQIDKEQHDKILDLIESGKKEGAKLECGGGR-WGNKGFFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFK--SVDDVIKRANNTTYGLAAGLFTKDLDKAITVSSALQAGVVWVNCYMMLSAQCPFGGFKMSGNGRELGEHGLYEYTELKTVAMKISQKNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51647-1", "uniprot_id": "AL1A1_RAT", "id": "P51647-1", "name": "Aldehyde dehydrogenase 1A1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSS-------------------PAQPAVPAPLANLKIQ-----------------------------------------------------------------HTKIFINNEWHDSVSGKKFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLMERDRLLLATIEAINGGKVFANAYLSDLGGSIKALKYCAGWADKIHGQTIPSDGD----IFTFTRREPIGVCGQIIPWNFPLLMFIWKIGPALSCGNTVVVKPAEQTPLTALHMASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTQVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDIAVEFAHHGVFYHQGQCCVAASRIFVEESVYDEFVRKSVERAKKYV-LGNPLTQGINQGPQIDKEQHDKILDLIESGKKEGAKLECGGGR-WGNKGFFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFK--SIDDVIKRANNTTYGLAAGVFTKDLDRAITVSSALQAGVVWVNCYMILSAQCPFGGFKMSGNGRELGEHGLYEYTELKTVAMKISQKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35945-1", "uniprot_id": "AL1A7_MOUSE", "id": "O35945-1", "name": "Aldehyde dehydrogenase, cytosolic 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSS-------------------PAQPAVPAPLANLKIQ-----------------------------------------------------------------HTKIFINNEWHDSVSSKKFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLMERDRLLLATMESMNAGKVFAHAYLLDVEISIKALQYFAGWADKIHGQTIPSDGN----IFTYTRREPIGVCGQIIPWNGPLIIFTWKLGPALSCGNTVVVKPAEQTPLTALHMASLIKEAGFPPGVVNIVPGYGPTAGGAISSHMDIDKVSFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDSAVEFAHQGVFFHQGQICVAASRLFVEESIYDEFVRRSVERAKKYI-LGNPLNSGINQGPQIDKEQHNKILGLIESGKKEGAKLECGGGR-WGNKGFFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFK--SMDDVIKRANNTTYGLAAGVFTKDLDKAITVSSALQAGMVWVNCYLAVPVQCPFGGFKMSGNGRELGEHGLYEYTELKTVAMQISQKNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00352-1", "uniprot_id": "AL1A1_HUMAN", "id": "P00352-1", "name": "Aldehyde dehydrogenase 1A1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSS-------------------SGTPDLPVLLTDLKIQ-----------------------------------------------------------------YTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWADKIQGRTIPIDGN----FFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYI-LGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGP-WGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFK--SLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKISQKNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62148-1", "uniprot_id": "AL1A2_MOUSE", "id": "Q62148-1", "name": "Retinal dehydrogenase 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSSEIAMPGEVKADPA--ALMASLQLLPSPTPNLEIK-----------------------------------------------------------------YTKIFINNEWQNSESGRVFPVCNPATGEQVCEVQEADKVDIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRATLATMESLNGGKPFLQAFYIDLQGVIKTLRYYAGWADKIHGMTIPVDGD----YFTFTRHEPIGVCGQIIPWNFPLLMFTWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVVNILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVKRSVERAKRRI-VGSPFDPTTEQGPQIDKKQYNKVLELIQSGVAEGAKLECGGKG-LGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFK--TMDEVIERANNSDFGLVAAVFTNDINKALMVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63639-1", "uniprot_id": "AL1A2_RAT", "id": "Q63639-1", "name": "Retinal dehydrogenase 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSSEIAMPGEVKADPA--ALMASLQLLPSPTPNLEIK-----------------------------------------------------------------YTKIFINNEWQNSESGRVFPVCNPATGEQVCEVQEADKVDIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRATLATMESLNGGKPFLQAFYIDLQGVIKTLRYYAGWADKIHGMTIPVDGD----YFTFTRHEPIGVCGQIIPWNFPLLMFTWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVVNILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVKRSVERAKRRI-VGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKG-LGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFK--TMDEVIERANNSDFGLVAAVFTNDINKALMVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O94788-1", "uniprot_id": "AL1A2_HUMAN", "id": "O94788-1", "name": "Retinal dehydrogenase 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSSKIEMPGEVKADPA--ALMASLHLLPSPTPNLEIK-----------------------------------------------------------------YTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGD----YFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRV-VGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKG-LGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFK--TMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4K6I6-1", "uniprot_id": "A0A0B4K6I6_DROME", "id": "A0A0B4K6I6-1", "name": "Aldehyde dehydrogenase domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMN------KLQKLLAHQLAVSRKWSKFDHTYAQCEPN-----------------------------------------------------------------YCQLFINNEFVDSVSGKTFATFNPATSKEIVQVSEGDKADIDLAVKAAKKAFHRDSEWRKLSPLQRTNLMNKLCALMDRDKAFLASLETQDNGKPYAEA-LFDVTYSILTLQYYAGWTDKFFGDTIPAGG-----FVSMTRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTALHMAALAKEAGFPAGVINVVNGFGPTAGAAISAHPDIAKVAFTGSVEIGRIVMQAAATSNLKRVSLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFVAKAAAKAKARK-VGNPFEQNVQQGPQIDDDMLTKVLGYIESGKKEGAKLQAGGKR-IGNVGFFVEPTVFSDVKDDMRIAQEEIFGPVQSIFKFS--SLEEMIDRANNVQYGLAAGVITNDINKALKFANNVDAGSVWINCYDAVLPSTPFGGYKHSGIGRELGKDGLDNYLETKTITMKLL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54115-1", "uniprot_id": "ALDH6_YEAST", "id": "P54115-1", "name": "Magnesium-activated aldehyde dehydrogenase, cytosolic", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTKLH--------------FDTAEPVKITLPNGLTYEQ-----------------------------------------------------------------PTGLFINNKFMKAQDGKTYPVEDPSTENTVCEVSSATTEDVEYAIECADRAFH-DTEWATQDPRERGRLLSKLADELESQIDLVSSIEALDNGKTLALA-RGDVTIAINCLRDAAAYADKVNGRTINTGDG----YMNFTTLEPIGVCGQIIPWNFPIMMLAWKIAPALAMGNVCILKPAAVTPLNALYFASLCKKVGIPAGVVNIVPGPGRTVGAALTNDPRIRKLAFTGSTEVGKSVAVDSSESNLKKITLELGGKSAHLVFDDANIKKTLPNLVNGIFKNAGQICSSGSRIYVQEGIYDELLAAFKAYLETEIKVGNPFDKANFQGAITNRQQFDTIMNYIDIGKKEGAKILTGGEK-VGDKGYFIRPTVFYDVNEDMRIVKEEIFGPVVTVAKFK--TLEEGVEMANSSEFGLGSGIETESLSTGLKVAKMLKAGTVWINTYNDFDSRVPFGGVKQSGYGREMGEEVYHAYTEVKAVRIKL-----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q3SY69-1", "uniprot_id": "AL1L2_HUMAN", "id": "Q3SY69-1", "name": "Mitochondrial 10-formyltetrahydrofolate dehydrogenase", "aln": "MLRRGSQALRRFSTGRVYFKNKLKLALIGQSLFGQEVYSHLR-KEGHRVVGVFTVPDKDGKADPLALAAEKDGTPVFKLPKWRVKGKTIKEVAEAYRSVGAELNVLPFCTQFIPMDIIDSPKHGSIIYHPSILPRHRGASAINWTLIMGDKKAGFSVFWADDGLDTGPILLQRSCDVEPNDTVDALYNRFLFPEGIKAMVEAVQLIADGKAPRIPQPEEGATYEG-IQKKENAEISWDQSAEVLHNWIRGHDKVPGAWTEING-----QMVTFYGSTLLNS-SVPPGEPLEIKGAKKPGLVTKNGLVLFGNDGKALTVRNLQFEDGKMIPASQYFSTGET-SVVELTAEEVKVAETIKVIWAGILSNVPIIEDSTDFFKSGASSMDVARLVEEIRQKCGGLQLQNEDVYMATKFEGFIQKVVRKLRGEDQ---EVELVVDYISKEVNEIMVKMPYQCFINGQFTDADDGKTYDTINPTDGSTICKVSYASLADVDKAVAAAKDAFENGE-WGRMNARERGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQGSTIPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVKAGFPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKSPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEESIHDEFVTRVVEEIKKMK-IGDPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGATLVYGGRQVQ-RPGFFMEPTVFTDVEDYMYLAKEESFGPIMVISKFQNGDIDGVLQRANSTEYGLASGVFTRDINKAMYVSEKLEAGTVFINTYNKTDVAAPFGGVKQSGFGKDLGEEALNEYLKTKTVTLEY-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O75891-1", "uniprot_id": "AL1L1_HUMAN", "id": "O75891-1", "name": "Cytosolic 10-formyltetrahydrofolate dehydrogenase", "aln": "----------------------MKIAVIGQSLFGQEVYCHLR-KEGHEVVGVFTVPDKDGKADPLGLEAEKDGVPVFKYSRWRAKGQALPDVVAKYQALGAELNVLPFCSQFIPMEIISAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFSIFWADDGLDTGDLLLQKECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGKAPRLPQPEEGATYEG-IQKKETAKINWDQPAEAIHNWIRGNDKVPGAWTEACE-----QKLTFFNSTLNTSGLVPEGDALPIPGAHRPGVVTKAGLILFGNDDKMLLVKNIQLEDGKMILASNFFKGAAS-SVLELTEAELVTAEAVRSVWQRILPKVLEVEDSTDFFKSGAASVDVVRLVEEVKELCDGLELENEDVYMASTFGDFIQLLVRKLRGDDE---EGECSIDYVEMAVNKRTVRMPHQLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFENGR-WGKISARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDEFVRRVVEEVRKMK-VGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVP-RPGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRVKTVTFEY-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIC9-1", "uniprot_id": "Q9VIC9_DROME", "id": "Q9VIC9-1", "name": "10-formyltetrahydrofolate dehydrogenase", "aln": "------------------MALKMRIAIIGQSNFAADVLELLLDRSNIQIVGVFTIPDKGSREDILATTATIHNIPVFKFACWRRKGVALPEVLEQYKSVGATLNVLPFCSQFIPMEVINGALLGSICYHPSILPRHRGASAISWTLIEGDEVAGFSIFWADDGLDTGPLLLTRQTNVESTDTLDTIYKRFLYPEGVKAMGVAVDMVASGTAPKIIQPEVGATYDPAMFKTENQVINLQATAEKIWNFVRGLDSVPGAIATVLHGNGTEEQIRLFGAHLYSAGPVSNGKVLRLRGLTKTAWIHSGGLLIEGTDGAFVNIRRIKR-GTKVISASEWFKQAEDQSITDFSEDELVKRSLLAGIWKAILK--EDVESSTDFFASGAGSMDVVRLVEEVKEAFD-VPLQNEQVFMAPVFEEFFSLLVRFLRQGSAGFGNQQLDFEAFTLKANKREIRVPTQLFINGEFVDAEAQRTLEIVNPTNEEVLCKVACASATDVDKAVRAAHSAFY-GS-WRQITPRQRGQLMLNLADLMERNKEELATIESVDSGAVYTLALKTHVGMSIEAWRYFAGWCDKIQGNTIPVNPARPNNVLTFTRKEPIGVCGLITPWNYPLMMLSWKMAACIAAGNTCLIKPAQTCPLTALKFAELTVRAGFPPGVINVLPGKGSDAGQAVADHELVRKLGFTGSTPIGKHIMKSCADSNLKKCSLELGGKSPLIIFADCDMDKAVKHGMSSVFFNKGENCIAAGRLFVEDRIHDEFIRRVLKDLRTMT-IGDPLDRSTAHGPQNHKAHFDKLLEFCRRGVDEGAKLVYGGCRVPNLKGYFFTPTVFTNVTDDMFIAQEESFGPIMIISKFNGSDIDSLMQRANRTEYGLASGVFTKDIGKALNFADRIEAGTVFVNVYNKTDVAAPFGGFKQSGYGKDLGQEALNEYLKTKCVTVEY-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . **...: .. : :*: . : .: . *:: *: .* ** . * . * .*: .*. :: . ::::*: : * : .: : : *.: ** * ** . . * **:** . * *** *::: ** ...:. * . ::* * .*.** .. * ..*:* **:*:: * * .* :: . : *:.****. :*: : .. :*:*: :*****:.. :: * ::. :: .:* : *: * :..* :*.: :: *:: . :*.*: :*. . :: * :**.: ** * *. **** * : * :.:** ***: : :* :: : ** :** :.: *..:. . . : :* *::* * **** * ** *:: *: * . * : .: ", "identical_positions": 109, "similar_positions": 152, "identity": "11.56%" }, { "cls_id": "homologset.agr.SGD:S000005984", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJX5-1", "uniprot_id": "D3ZJX5_RAT", "id": "D3ZJX5-1", "name": "Mitochondrial import inner membrane translocase subunit TIM50", "aln": "-------------------------MAASAALFSRLRSG---LRVGARGLCTRLAPP---------PPRTPEQVTEIANRGGS----------------------------KTQGPQHQPGSEG-------------------PSYAKKVALWIAGLLGAGGTVSIVYIFGNNPVDENGTKVRRSVFCKDPILVQQLRRTYKYFKDYRQMIIEPTSPCLLPDPLREPYYQPPYTLVLELTGVLLHPEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDP-HGFISYRLFRDATRYMEGHHVKDISCLNRDPARVVVVDCKKEAFRLQPFNGVALRPWDGNSDDRVLLDLSAFLKTIALNQVEDVRTVLEHYALEDDPLEAFKQRQSRLE---------------------------------------------------QEEQQRLAELSKSNKQGLFFGSLTSRLWPRSKQP----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D880-1", "uniprot_id": "TIM50_MOUSE", "id": "Q9D880-1", "name": "Mitochondrial import inner membrane translocase subunit TIM50", "aln": "-------------------------MAASAALFSRLRSG---LRVGARGLCTRLAPP---------PPRTPEQVTEIANRGGS----------------------------KAQGPQHQPGSEG-------------------PSYAKKIALWIAGLLGAGGTVSIVYIFGNNPVDENGTKIP-DEFDSDPILVQQLRRTYKYFKDYRQMIIEPTSPCLLPDPLREPYYQPPYTLVLELTGVLLHPEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDP-HGFISYRLFRDATRYMEGHHVKDISCLNRDPARVVVVDCKKEAFRLQPFNGVALRPWDGNSDDRVLLDLSAFLKTIALNQVEDVRTVLEHYALEDDPLEAFKQRQSRLE---------------------------------------------------QEEQQRLAELSKSNRQGLSFGSLASRLWPRSKQP----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3ZCQ8-1", "uniprot_id": "TIM50_HUMAN", "id": "Q3ZCQ8-1", "name": "Mitochondrial import inner membrane translocase subunit TIM50", "aln": "-------------------------MAASAAVFSRLRSG---LRLGSRGLCTRLATP---------PRRAPDQAAEIGSRGST----------------------------KAQGPQQQPGSEG-------------------PSYAKKVALWLAGLLGAGGTVSVVYIFGNNPVDENGAKIP-DEFDNDPILVQQLRRTYKYFKDYRQMIIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLHPEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDP-HGFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWDGNSDDRVLLDLSAFLKTIALNGVEDVRTVLEHYALEDDPLAAFKQRQSRLE---------------------------------------------------QEEQQRLAELSKSNKQNLFLGSLTSRLWPRSKQP----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NWD4-1", "uniprot_id": "TIM50_DANRE", "id": "Q6NWD4-1", "name": "Mitochondrial import inner membrane translocase subunit TIM50", "aln": "-------------------------MSAVSVYPMCVRASRGLLRLRQGARCSTAPPL---------LDVVRPLSADTSSSSATGGLAQAI---------------LQERLQQQQKSQEQPPPEGEDSGHKQDEQGEDKKQKENTAYAKKMVLRLAGIMGLGGTVGIVYIFGSNSVDEQGNKIP-DEFDNDVPVIQQLRRTFKYFKDYRQMIIEPTSPKLLPDPLREPYYQPPYTLVLELTDVLLHPEWSLATGWRFKKRPGIDYLFQQLAPLYEIVIFTSETGMTAYPLIDSIDP-QGFVMYRLFRDATRYMEGHHVKDVSCLNRDTSKVIVVDCKREAFGLQPFNGLALCKWDGNSEDRTLYDLAAFLKTIATSGVEDVRSVLENYAHEEDPIEAFKRRQAQLA---------------------------------------------------REEEQRISEMAQQKKQGFSLGTIAGRFWSRKQQ-----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0S3-1", "uniprot_id": "TI50B_DROME", "id": "Q9W0S3-1", "name": "Mitochondrial import inner membrane translocase subunit TIM50-B", "aln": "----MSLIAIERVLCGWPK-ICRKLIVTSRSLTSGLRRALVKQPRKGGDVGKPGMELGRCSCFGLRVNLSNASVVYVGHRRYSTYEKTST---------------QILTKLFPQTSEESNDEESRERRKLEEEEEQKELERAFRRMK--LGFGLFGIGSMLFSFWAIYFYGRPSLD-EHGNEVIDEFSCLPQMQQLMWRTWKSVNRFQRFFKEPSRKKLLPDPLQPPYVQPPYTLVLEIKDVLVHPDWTYETGWRFKKRPGVDVFLKECAKYFEIVVYTAEQGVTVFPLVDALDP-NGCIMYRLVRDSTHFDGGHHVKNLDNLNRDLKRVVVVDWDRNSTKFHPSNSFSIPRWSGNDNDTTLFELTSFLSVLGTSEIDDVREVLQYYNQFSDSLSQFRENQRKLG---------------------------------------------------ELMHAEEV-EKTSKSR-PVVKNWTRGFINH--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W4V8-1", "uniprot_id": "TI50C_DROME", "id": "Q9W4V8-1", "name": "Mitochondrial import inner membrane translocase subunit TIM50-C", "aln": "MSMSMAPATVLQLLRGLSTPRLLTHIHQHRALGNHYHHYHQHYQHQHHLLHHQQQYLRLFTCTALPAAAPALFSILHTARGYSSTTKQEAGATGPNDAPEVAPNAPLLAKLFPQTSPEVDSNAEQERKKREEEEE-KENERAWKRMK--LGFAIFGGSAVAAGFWAVYEFGKPEVD-PNGQPIEDEFTHKPLVQQYLQRMWKSIHYYQRMIQEPSRAKLLPDPLKPPYVQPRYTLVLEMKDVLVHPDWTYQTGWRFKKRPGVDHFLAECAKDFEIVVFTAEQGMTVFPILDALDP-NGYIMYRLVRDATHFVDGHHVKNLDNLNRDLKKVIVVDWDANATKMHPDNTFGLARWHGNDDDGQLLDLIAFLKIIAQNNVDDVREVLHYYRQFDDPINQFRENQRKLA---------------------------------------------------EQMLEAER-IEQSKTK-PMVKQWSRNILGR--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9P3-1", "uniprot_id": "TI50A_DROME", "id": "Q9V9P3-1", "name": "Mitochondrial import inner membrane translocase subunit TIM50-A", "aln": "----------------------MHKIVWFGTLN-----------KSIGYIGKKKTCL----------LSPCEKICLNSAR---------------------------------KTVQRCDKNYSPPK---------------LRRIKNFYTYSVVLGSLFSIVMWAIYKLGKPEED-HRG-PIEDEFSQLPWFRQYIMRMWHTLQYYEKMMEEPQMARLLPNVVPPPYIQPPYSLVLEIKDVLVHPDWTYQTGWRFKKRPGVDYFLQQCSRNFEIVIYTSEQGMTAFPLLDALDP-YGYIKYRLVRGATDLVEGQHTKNLDYLNRDLSRVIVVDCDPYTTPLHPDNSLVLTKWLGNDDDVQLFDLTAFLQLIAEHQVNDVREVLRYYRQFEDPMEQFKDNQRRLQ---------------------------------------------------EQSQESIQNLPTSERQ-WNLTLLGRSLRGSSIK-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02776-1", "uniprot_id": "TIM50_YEAST", "id": "Q02776-1", "name": "Mitochondrial import inner membrane translocase subunit TIM50", "aln": "-------MLSILRNSVRLNSRALRVVPSAANTLTSVQASRRLLTSYSSFLQKETKDDKPKSILTDDMLFKAGVDVDEKGQGKN-----------------------------EETSGEGGEDKNEPSSKSEKSRRKRQTSTDIKREKYANWFYIFSLSALTG----TAIYMARDWEPQESEELKKDIDNGYTLSLMYKRFKARFNSMFTYFQEPPFPDLLPPPPPPPYQRP-LTLVITLEDFLVHSEWSQKHGWRTAKRPGADYFLGYLSQYYEIVLFSSNYMMYSDKIAEKLDPIHAFVSYNLFKEHCVYKDGVHIKDLSKLNRDLSKVIIIDTDPNSYKLQPENAIPMEPWNGEADDK-LVRLIPFLEYLATQQTKDVRPILNSFEDKKNLAEEFDHRVKKLKDKFYGDHKSGGNWAMTALGLGNSLGGSTKFPLDLIHEEGQKNYLMFMKMIEEEKEKIRIQQEQMGGQTFTLKDYVEGNLPSPEEQMKIQLEKQKEVDALFEEEKKKKKIAESK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : : . : . * .: : ** *** ** :* :**: : ..*:*.:*: *** **** : :: : :***::::: : : : :** . : *.*.: * * *::. **** :*:::* . : ::* * . : * *: :* * * .**. :. .*** :*. : .: * . :* . : . ", "identical_positions": 52, "similar_positions": 70, "identity": "10.04%" }, { "cls_id": "homologset.agr.SGD:S000005985", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIB2-1", "uniprot_id": "CWC27_RAT", "id": "Q5XIB2-1", "name": "Spliceosome-associated protein CWC27 homolog", "aln": "MSNIYIQEPPTNGKVLLKTTAGDIDIELWSKEAPKACRNFIQLCLEAYYDNTIFHRVVP-GFIVQGGDPTGTGTGGESVYGAPFKDEFHSRLRFNRRGLVAMANAGPHDNGSQFFFTLGRADELNNKHTIFGKVTGDTVYNMLRLTEVDIDDEERPRNPHRIKSCEVLFNPFDDIIPREIKKPKKEKAEEEIKKLKPKGTKNFSLLSFGEEAEEEEEEVNRVSQSMKGRSKSSHDLLKDDPHLS--SVPAVESEKDDATGDLEDDAEDDSVEHDGSMEEDEKNLMRERIAKRLKKDASANVKSAGDG------------EKKPASR--SEE---LRKEARQLKRELLAAKQKKES--ATKAEKGSEEEEAVPDG---PVAEYRREKQKYEALRKQQPKKGTSREDQTLALLSQFKSKLTQAITEM---PEN-CAEAEVEDD---------EGWMSHVLQFEDKT-RKVKDASMQDSDTFEIYDPRNPVNKRRREES----KKLLREKKERR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TKY6-1", "uniprot_id": "CWC27_MOUSE", "id": "Q3TKY6-1", "name": "Spliceosome-associated protein CWC27 homolog", "aln": "MSNIYIQEPPTNGKVLLKTTAGDIDIELWSKEAPKACRNFIQLCLEAYYDNTIFHRVVP-GFIVQGGDPTGTGTGGESIYGAPFKDEFHSRLRFNRRGLVAMANAGPHDNGSQFFFTLGRADELNNKHTIFGKVTGDTVYNMLRLTEVDIDDEERPRNPHRIKSCEVLFNPFDDITPREIKKPKNEKPEEEVKKLKPKGTKNFSLLSFGEEAEEEEEEVNRVSQSMKGRSKSSHDLLKDDPHLS--SVPAVESEKDDATGDLEDDGEDDSAERDEYMEDDEKNLMRERIAKRLKKDASASVKSAGDG------------EKKPASR--SEE---LRKEARQLKRELLAAKQKKET--AIKVEEGREEEEAAPDG---AVAEYRREKQKYEALRKQQPKKGTSREDQTLALLSQFKSKLTQAITET---PENSVPEAEVEDD---------EGWMSHVLQFEDKT-RKVKDASMQDSDTFEIYDPRNPVNKRRREES----KKLLREKKERR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UX04-1", "uniprot_id": "CWC27_HUMAN", "id": "Q6UX04-1", "name": "Spliceosome-associated protein CWC27 homolog", "aln": "MSNIYIQEPPTNGKVLLKTTAGDIDIELWSKEAPKACRNFIQLCLEAYYDNTIFHRVVP-GFIVQGGDPTGTGSGGESIYGAPFKDEFHSRLRFNRRGLVAMANAGSHDNGSQFFFTLGRADELNNKHTIFGKVTGDTVYNMLRLSEVDIDDDERPHNPHKIKSCEVLFNPFDDIIPREIKRLKKEKPEEEVKKLKPKGTKNFSLLSFGEEAEEEEEEVNRVSQSMKGKSKSSHDLLKDDPHLS--SVPVVESEKGDAP-DLVDDGEDESAEHDEYIDGDEKNLMRERIAKKLKKDTSANVKSAGEGE----------VEKKSVSR--SEE---LRKEARQLKRELLAAKQKKVENAAKQAEKRSEEEEAPPDG---AVAEYRREKQKYEALRKQQSKKGTSREDQTLALLNQFKSKLTQAIAET---PENDIPETEVEDD---------EGWMSHVLQFEDKS-RKVKDASMQDSDTFEIYDPRNPVNKRRREES----KKLMREKKERR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZW86-1", "uniprot_id": "CWC27_DANRE", "id": "Q7ZW86-1", "name": "Spliceosome-associated protein CWC27 homolog", "aln": "MSNIYIQEPPTNGKVLLKTSAGDIDIELWSKETPKACRNFVQLCMEGYYDGTIFHRMVP-EFIVQGGDPTGTGTGGESIYGRPFKDEFHSRLRFNRRGLVAMANAGPHDNGSQFFFTLGRADELNNKHTIFGKVTGDTVYNMLRLADVACDGDERPLNPHKIRSTEVLHSPFDDIIPREIKG-KKEKNKDEAKKSQSKATKNFSLLSFGEEAEEDEEMVNQVSQTMKGKSKSSHDLLKDDPKLS--SVPVVD--RNQGEGDFEDSDDDEDDAEDDSDREAEKAKVRENIAKKLKKDKTDEEKSSQDL-------------VKKTSR--SDE---LRKEARQLKKELLAIKQRKED-GVKKEEDVSEVGDSKQNSE--AVTEYLESRKKYDDMRKQKLKKGSGREAQTLALLESFKSKLSSAISETPSAPEEDVEELAEDDD---------KGWMAHVLHFDEQS-RKVKDANMQDEDTFEIYDPRNPVNKRRREES----KKLLKDKKARR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTN7-1", "uniprot_id": "Q9VTN7_DROME", "id": "Q9VTN7-1", "name": "Spliceosome-associated protein CWC27 homolog", "aln": "MSNIYIQEPPTSGKVLLKTTVGDIDIELWARECPKACRNFVQLCLEGYYKNTEFHRLVK-GFIVQGGDPNGDGTGGESIYGQPFKDEFHSRLRYTRRGLVGMANSGKDDNGSQFFFTFAPTPELQNKNTLFGKITGDTIYNMLKLEDGIVDHQERPMHAHRIVSTEVLSNPFDDIVPRILSQPSTKSKK---TKKERQGVKNFGLLSFGEEAEGDEEETNVYVKQNAGKAKSLHDVT-DDPKLSKEPIRVPKVEKADIEEHLSDDCPEDSVKDKPS--TASSDLIKMKLSKRSKSGADKKVQPVEEKSDSEDDEDVLLTREEEQSRKVSEEKSKIREEIASLKKQYQMDKQSKDK-LVNGQEKAAKSNEIKGSSENHYINDFIESKEKYTAKVKLQPK-GQSREAFTLSLLSKFRTKLDNLKQKS--SSDDGESEPKDIDDRVVEQEIIGDDWLSHTLNFNSTTPVLAKDANKKGDDWYDAYDPRNPLNKRKRGETGSSKSSSGKSKSSKRDF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02770-1", "uniprot_id": "CWC27_YEAST", "id": "Q02770-1", "name": "Peptidyl-prolyl isomerase CWC27", "aln": "MS--SNIEPQTTAKCILYTTKGNIAIELWAKECPETCKRFLSMLSDGTFTNGEFKELKPTQWLMFNANSTGEYR--------TVAEEKNPRIRFNRDGLLGWDRR----RNTWFITVLADSKHVLNDCNVFGKIVGKSIYIFREILGGEIEASSRDNDVKRFMYPAVLKDVEITIPFFEDIFGSKRRLEDNEKKEQEPAKKLVKSAKVKMVYEDEQEDDDGDVQKLKPRK------------------------RMILPAWIKDDSRSEGIKLDASLDQPQEALIREKTELHDNVDEATTKETESQEN----------------IKEEPMD----------------------------------------------------------------------KRERETLAMLSKFQERIKNKNILK----------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ** *..* :* *: *:* ****::* *::*:.*:.: :. : . *:.: ::: ..:..* .. :* :.*:*:.* **:. . ..: *: .:. : .: *. .:***:.*.::* : .: : ..* . ::: ** . * ... : .* : . * . .. * ::* : : : : : *. .:. . .. :: . : : . :. : : . : ** **::*..*: :: . ", "identical_positions": 48, "similar_positions": 113, "identity": "9.36%" }, { "cls_id": "homologset.agr.SGD:S000005986", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DEN9-1", "uniprot_id": "VPS28_RAT", "id": "B5DEN9-1", "name": "Vacuolar protein sorting-associated protein 28 homolog", "aln": "-MFHGIPATPGVGALPCSVAAPGNKPELYEEVKLYKN---AREREKYDNMAELFAVVKTMQALEKAYIKDCVTPNEYTAACSRLLVQYKAAFRQVQGSEIS----SIDEFCRKFRLDCPLAMERIKEDRPITIK-------------------DDKGNLNRCIADVVSLFITVMDKLRLEIRAMDEIQPDLRELMETMHRMSHLPPDFEGRQTVSQWLQTLSGMSASDELDDSQVRQMLFDLESAYNAFNRFLHS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D1C8-1", "uniprot_id": "VPS28_MOUSE", "id": "Q9D1C8-1", "name": "Vacuolar protein sorting-associated protein 28 homolog", "aln": "-MFHGIPATPGVG-------APGNKPELYEEVKLYKN---AREREKYDNMAELFAVVKTMQALEKAYIKDCVTPNEYTAACSRLLVQYKAAFRQVQGSEIS----SIDEFCRKFRLDCPLAMERIKEDRPITIK-------------------DDKGNLNRCIADVVSLFITVMDKLRLEIRAMDEIQPDLRELMETMHRMSHLPPDFEGRQTVSQWLQTLSGMSASDELDDSQVRQMLFDLESAYNAFNRFLHA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UK41-1", "uniprot_id": "VPS28_HUMAN", "id": "Q9UK41-1", "name": "Vacuolar protein sorting-associated protein 28 homolog", "aln": "-MFHGIPATPGIG-------APGNKPELYEEVKLYKN---AREREKYDNMAELFAVVKTMQALEKAYIKDCVSPSEYTAACSRLLVQYKAAFRQVQGSEIS----SIDEFCRKFRLDCPLAMERIKEDRPITIK-------------------DDKGNLNRCIADVVSLFITVMDKLRLEIRAMDEIQPDLRELMETMHRMSHLPPDFEGRQTVSQWLQTLSGMSASDELDDSQVRQMLFDLESAYNAFNRFLHA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V359-1", "uniprot_id": "VPS28_DROME", "id": "Q9V359-1", "name": "Vacuolar protein sorting-associated protein 28 homolog", "aln": "--------------------MQEQSPELYEEVKLFRN---AREREKYDNMADLYAIINTIQQLEKAYIRDCITPQEYTAACSKYLVQYKVAFKQVQCDEFP----SVETFVKKFRLDCPAALERIREDRPITIR-------------------DDKGNTSKCIAEIVSLFITIMDKLRLQINTMDALQPDVKDLADNMNRLSLIPEDFDAKLKVEKWLGSLNEMQASDELSEGQVRQFLFDLESAYADFNKLLHSQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02767-1", "uniprot_id": "VPS28_YEAST", "id": "Q02767-1", "name": "Vacuolar protein sorting-associated protein 28", "aln": "MQKHNIKLN----------QNQDISQLFHDEVPLFDNSITSKDKEVIETLSEIYSIVITLDHVEKAYLKDSIDDTQYTNTVDKLLKQFKVYLNSQNKEEINKHFQSIEAFCDTYNITASNAITRLERGIPITAEHAISTTTSAPSGDNKQSSSSDKKFNAKYVAEATGNFITVMDALKLNYNAKDQLHPLLAELLISINRVTR--DDFENRSKLIDWIVRINKLSIGDTLTETQIRELLFDLELAYKSFYALLD--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :::** *: * ::::* :.:::::::: *:: :****::*.: :** : .: * *:*. :.. : .*: *:: * .:.: .. *: *:... *** . .** : :*: .. ***:** *:*: .: * ::* : :* .::*:: **: : .: .*: :. :. .* * : *:*::***** ** * :*. ", "identical_positions": 54, "similar_positions": 89, "identity": "21.09%" }, { "cls_id": "homologset.agr.SGD:S000005990", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6F596-1", "uniprot_id": "GGPPS_RAT", "id": "Q6F596-1", "name": "Geranylgeranyl pyrophosphate synthase", "aln": "------------------------------------------MEKTKEKAERILLEPYKYLLQLPGKQVRTKLSQAFNHWLKVPEDKLQIIIEVTEMLHNASLLIDDIEDSSKLRRGFPVAHSIYGVPSVINSANYVYFLGLEKVLTLDHPD-----AVKLFTRQLLELHQGQGLDIYWRDTY--TCPTEEEYKAMVLQKTGGLFGLAVGLMQLFS---DYKEDLKPLLDTLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIWSRP------ESTQVQNILRQRTENIDIKKYCVQYLE-DVGSFEYTRYTLRELEAKAYKQIEACGGNPSLVALVKHLSKMFTEENE--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTN0-1", "uniprot_id": "GGPPS_MOUSE", "id": "Q9WTN0-1", "name": "Geranylgeranyl pyrophosphate synthase", "aln": "------------------------------------------MEKTKEKAERILLEPYRYLLQLPGKQVRSKLSQAFNHWLKVPEDKLQIIIEVTEMLHNASLLIDDIEDSSKLRRGFPVAHSIYGVPSVINSANYVYFLGLEKVLTLDHPD-----AVKLFTRQLLELHQGQGLDIYWRDTY--TCPTEEEYKAMVLQKTGGLFGLAVGLMQLFS---DYKEDLKPLLDTLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIWSRP------ESTQVQNILRQRTENIDIKKYCVQYLE-DVGSFAYTRHTLRELEAKAYKQIEACGGNPSLVALVKHLSKMFTEENK--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95749-1", "uniprot_id": "GGPPS_HUMAN", "id": "O95749-1", "name": "Geranylgeranyl pyrophosphate synthase", "aln": "------------------------------------------MEKTQETVQRILLEPYKYLLQLPGKQVRTKLSQAFNHWLKVPEDKLQIIIEVTEMLHNASLLIDDIEDNSKLRRGFPVAHSIYGIPSVINSANYVYFLGLEKVLTLDHPD-----AVKLFTRQLLELHQGQGLDIYWRDNY--TCPTEEEYKAMVLQKTGGLFGLAVGLMQLFS---DYKEDLKPLLNTLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIWSRP------ESTQVQNILRQRTENIDIKKYCVHYLE-DVGSFEYTRNTLKELEAKAYKQIDARGGNPELVALVKHLSKMFKEENE--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z9I5-1", "uniprot_id": "A0A8M6Z9I5_DANRE", "id": "A0A8M6Z9I5-1", "name": "Geranylgeranyl pyrophosphate synthase", "aln": "MLASWLTVEKKTESGRVTCWITEAEVTERRFSFWKVWIYRGMDEKQRATSERILLEPYKYLLQLPGKQVRTKLSQAFNHWLNVPEDKLQVIIEVTEMLHNASLLIDDIEDSSKLRRGFPVAHSIYGIPSVINSANYVYFLGLEKVLMLEHPE-----AVRVFTRQLLELHRGQGLDIHWRDTY--TCPSEAEYRAMVLQKTGGLFGLAVGLMQLFS---DWKRDLKPLLDTLGLYFQIRDDYANLNSKEYSANKSFCEDLTEGKFSFPTIHAIWSHP------ESTQVQNILRQRTENLDIKRYCVDYLE-KVGSFAYTRQTLLDLEVEAYRLIKELGGNPELEALVEHLSRMYKEPEGGATVSQSK------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VS54-1", "uniprot_id": "Q9VS54_DROME", "id": "Q9VS54-1", "name": "", "aln": "------------------------------MEELNIILQKTKDKSTQKEQDEILLQPFTYIQQIPGKQFRSELALAFNHWLLIPGEKLAQIGDIVQMLHNSSLLIDDIEDNSILRRGVPVAHSIYGVASTINAANYALFLALEKVQQLDHPE-----ATKVYTEQLLELHRGQGMEIYWRDSF--TCPSESDYKLMTVRKTGGLFMLAIRLMQLFS---SNKEDYSKLTAILGLYFQIRDDYCNLSLKEYTENKSFAEDLTEGKFGFPVIHAVRTQK------QDKQVLHILRQRTHDIEVKKYCITLLE-KLGSFQYTRKVLESLDAEARSEVARLGSNPYMDRLLNKLLSWKTSDSASITQSNQINHNNVSRSSPNQNTLNCN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12051-1", "uniprot_id": "GGPPS_YEAST", "id": "Q12051-1", "name": "Geranylgeranyl pyrophosphate synthase BTS1", "aln": "-------------------------------MEAKIDELINNDPVWSSQNESLISKPYNHILLKPGKNFRLNLIVQINRVMNLPKDQLAIVSQIVELLHNSSLLIDDIEDNAPLRRGQTTSHLIFGVPSTINTANYMYFRAMQLVSQLTTKEPLYHNLITIFNEELINLHRGQGLDIYWRDFLPEIIPTQEMYLNMVMNKTGGLFRLTLRLMEALSPSSHHGHSLVPFINLLGIIYQIRDDYLNLKDFQMSSEKGFAEDITEGKLSFPIVHALNFTKTKGQTEQHNEILRILLLRTSDKDIKLKLIQILEFDTNSLAYTKNFINQLVN----MIKNDNENKYLPDLASHSDTATNLHDELLYIIDHLSEL---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :*: :: ***:.* :* :*: : :* ::* : ::.::***:*********.: **** ..:* *:*:.*.**:*** * .:: * * : ::..:*::**:***::*:*** *:: * *.:.****** *:: **: :* .. : **: :****** ** : : :*.*.**:****:.** :**: : .:: .** ** : ::* : ** . .*: **: : .* : . * : * .: . . ", "identical_positions": 95, "similar_positions": 94, "identity": "24.68%" }, { "cls_id": "homologset.agr.SGD:S000005995", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BPY9-1", "uniprot_id": "FIGL1_MOUSE", "id": "Q8BPY9-1", "name": "Fidgetin-like protein 1", "aln": "---------------------------METSSSMSVETTRSVQVDEWQKNYCVVTSSICTPKQKADAYRALLLHIQYAYANSEISQVFATNLFKRYTEKYSAIIDSDNVVTGLNNYAESIFALAGSRQ------------------------------------------ADSNKWQSGLSIDNVFKMSCVQEMMQAGKKFEESLLEPADASVVLCKE-----------------------------PTAFEVP---------------QLSVCGGSEDADILSSSGHDTDKTQAIPGSSLRCSPFQSARLPKETNTTKTCLTSSTSLGESATAAFHMTPLFGNTEKDTQSFPKTSTGLNMFLSNLSCVPSGCENPQERKAFNDSDIIDILSNPTLNKAPSKTEDRGRREDNSLPTFKTAKEQLWVDQKKKGHQSQHTSKSSNG-------VMKKSLGAGRSRGIFGKFVPPVSNKQDGSEQH-AKKHKSSRAGSAEPAHLTDDCLKN-----------------VEPRMVELIMNEIMDHGPPVHWDDIAGVEFAKATIKEIVVWPMMRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSE----------DRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVGNLMSKEQCCLSDEETDLVVQQSDGFSGADMTQLCREASLGPIRSLHAADIATISPDQVRPIAYIDFENAFKTVRPTVSPKDLELYENWNETFGCGK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6GX84-1", "uniprot_id": "FIGL1_RAT", "id": "Q6GX84-1", "name": "Fidgetin-like protein 1", "aln": "---------------------------METSS------SRSVQVDDWQKNYSVVASSICTPKQKADAYRALLLHIQDAYANSEISQVFATNLFKRYTEKYSAIIDSDNVVTGLNNYAESIFALAGSQQ------------------------------------------ADSDKWQSGLSINNVFKMSTVQEMMQAGQKFKESLLEPADASVVMCKE-----------------------------PTIFEVP---------------QLGVCGGSEEADLLSSSVHGTEKTQAIPGNSLRCSPFQSTLFPMATN-TKTCLTSSAPSGESTTATFHRTPLFGNTKKEPQSFPKTSTGLNMFLSNPSCVPSGCENPRERKAFNDSDTINMLSNPTLNKAPSKTEDSGQREDNSLPTFKTAKEQLWADQKKRSHQSQHTSKSFNG-------AIKKSLGAGRSRGIFGKFVPPVSNKQDGSEQNGNVKPKSSRAGSAEPAHLTDDRLKN-----------------VEPRMVELIMNEIMDHGPPVHWEDIAGVEFAKATIKEIVVWPMMRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSE----------DRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVVNLMSKEQCCLTDEETELVVQQSDGFSGADMTQLCREASLGPIRSLHTADIATISPDQVRPIAYIDFENAFRTVRPSVSPKDLELYENWNKTFGCGK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PIW4-1", "uniprot_id": "FIGL1_HUMAN", "id": "Q6PIW4-1", "name": "Fidgetin-like protein 1", "aln": "---------------------------MQTSS------SRSVHLSEWQKNYFAITSGICTG-PKADAYRAQILRIQYAWANSEISQVCATKLFKKYAEKYSAIIDSDNVESGLNNYAENILTLAGSQQ------------------------------------------TDSDKWQSGLSINNVFKMSSVQKMMQAGKKFKDSLLEPALASVVIHKE-----------------------------ATVFDLP---------------KFSVCGSSQESDSLPNSAHDRDRTQDFP-ESNRLKLLQNAQPPMVTNTARTCPTFSAPVGESATAKFHVTPLFGNVKKENHSSAKENIGLNVFLSNQSCFPAACENPQ-RKSFYGSGTIDALSNPILNKACSKTEDNGPKEDSSLPTFKTAKEQLWVDQQKKYHQPQRASGSSYG-------GVKKSLGASRSRGILGKFVPPIP-KQDGGEQNGGMQCKPYGAGPTEPAHPVDERLKN-----------------LEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSE----------DRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRSLQTADIATITPDQVRPIAYIDFENAFRTVRPSVSPKDLELYENWNKTFGCGK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQN8-1", "uniprot_id": "FIGL1_DROME", "id": "Q9VQN8-1", "name": "Fidgetin-like protein 1", "aln": "------------------------------------------------------------MSDEQSSWRSKLLLICQQTRSSSESIHFAA----------------------LKDHHARLQACESMEK------------------------------------------AMKERCQKKITMS---------RRTKRGITHAGYLFEMPHN-------------------------------------SVFEPE---------------CRGFYESCQQTEMASS-------------------DLQAPALEVSSTYPVQQAVKSRPEGQFPESRNNSTKKIDAQQYSSESSSQSGFG----------------------------------------------------------FRTAREQLIMDELKK---KNRQATSEVD-------AVPTGMMNFRKKTLGGKRTVSSNFVSPVAQNDNSTSSRSS---------SIPPALAH-----------------LDSKMVDHILGESMHDFKPVAWEDIAGLESAKSTFLEAIIMPLRRPDLFTGVRCPPRGVLLFGPPGTGKTLIAKSIASQAKAKFFSINPSSLTSKWVGDAEKLVKTLFAVAAAHQPAIIFIDEVDSLLSKRSANENESTLRLKNEFLIHLDGAASNEE----------IRVLVIGATNRPQELDEAVRRRFVRRLYVPLPTREARQKIIEKLIHQVKHNLDVRQVIELAELTDGYSGADVDTLCRYASMAPLRSLTPDQMEVIETHQLPAVTMDDFKQALRVISKSVSSEDCKQFEAWNEIYGVRH--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9QYY8-1", "uniprot_id": "SPAST_MOUSE", "id": "Q9QYY8-1", "name": "Spastin", "aln": "--------------------------------------------------------------------------MSSPAGRRKKKGSGGAS---------PAPARPPPPAAVPAP-AAGPAPAAG---------------------------------------------SPPKRNPSSFSSPLVVGFALLRLLACHLGLLFAWLCQRFSRALMAAKR-----------------------------SSGTA------------------PAPASPSPPEPGPGG-EAESVRVFHKQAFEYISIALRIDEEEKAGQKEQAVEWYKKGIEELEKGIAVIVT-GQGEQYERARRLQAKMMTNLVMAKDRLQLLEKLQPVLQFSKSQTDVYNESTNLTCRNGHLQSESGAVPKRKDPLTHASNSLPRSKTVLKSGSAGLSGHHRAP--------SCSGLSMVSGARPGPGPAATTHKGTPKPNRTNKPSTP--------TTAVRKKKDLKN--------------FRNVDSNLANLIMNEIVDNGTAVKFDDIAGQELAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSAGD----------DRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKDFGDTTV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2RYN7-1", "uniprot_id": "SPAST_RAT", "id": "B2RYN7-1", "name": "Spastin", "aln": "--------------------------------------------------------------------------MSSPAGRRKKKGSGGAS---------PAPARPPPPAAVPAP-AAGPAPAPG---------------------------------------------SPHKRNLYYFSYPLVVGFALLRLLACHLGLLFVWLCQRFSRALMAAKR-----------------------------SSGTA------------------PAPASPSTPAPGPGG-EAESVRVFHKQAFEYISIALRIDEEEK-GQKEQAVEWYKKGIEELEKGIAVIVT-GQGEQYERARRLQAKMMTNLVMAKDRLQLLE--------------------------------SGAVPKKKDPLTHASNSLPRSKTVMKSGSTGLSGHHRAP--------SCSGLSMVSGARPGSGPAATTHKGTSKPNRTNKPSTP--------TTAVRKKKDLKN--------------FRNVDSNLANLIMNEIVDNGTAVKFDDIAGQELAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSAGD----------DRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKDFGDTTV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBP0-1", "uniprot_id": "SPAST_HUMAN", "id": "Q9UBP0-1", "name": "Spastin", "aln": "--------------------------------------------------------------------------MNSPGGRGKKKGSGGASN--------PVPPRPPPPCLAPAPPAAGPAPPPE---------------------------------------------SPHKRNLYYFSYPLFVGFALLRLVAFHLGLLFVWLCQRFSRALMAAKR-----------------------------SSGAA------------------PAPASASAPAPVPGG-EAERVRVFHKQAFEYISIALRIDEDEKAGQKEQAVEWYKKGIEELEKGIAVIVT-GQGEQCERARRLQAKMMTNLVMAKDRLQLLEKMQPVLPFSKSQTDVYNDSTNLACRNGHLQSESGAVPKRKDPLTHTSNSLPRSKTVMKTGSAGLSGHHRAP--------SYSGLSMVSGVKQGSGPAPTTHKGTPKTNRTNKPSTP--------TTATRKKKDLKN--------------FRNVDSNLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSAGD----------DRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKDFGDTTV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NW58-1", "uniprot_id": "SPAST_DANRE", "id": "Q6NW58-1", "name": "Spastin", "aln": "--------------------------------------------------------------------------MNSG---HKARLRGGR--------------------------ACGPVSDGS---------------------------------------------ARGNRLLFYTRSLSRVPEWLLRVLL----LLLRWLFQPIRRAMAARAK-----------------------------ECGPD------------------GSEETG------------ERIRNYHKQAFEFISVALQIDEDEK-GDKQKAVQWYRKGIAELEKGIQIQVT-GAGEKADRARKLQDKMITNLSMAEDRLKLLGNLLSQSPAESSSDDSFYSFSN---GNLRPAPASGAVSKKKDTLTITNQTSLRPKNPPKS-TPNASGLNCTP--------SAAQSSRTGPQNNQKGP---TVKGK---NNVKASTTA--------TASPQRKRDMKN--------------FKNVDSKLASLILNEIVDSGSVVRFDDIAGQDLAKQALQEIVILPALRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAMESNATFFNISAATLTSKYVGEGEKLVRALFAVARELQPSIIFIDEIDSLLCERREGEHDASRRLKTEFLIEFDGVQSGGD----------ERVLVMGATNRPQELDEAVLRRFAKRIYVALPTEETRLKLLKNLLSKHRNPLSQKELSQLARLTDGYSGSDLTSLAKDAALGPIRELKPEQVRNMSAHEMRDIRISDFLESLKRIKRSVSPQTLDQYVRWNREYGDTTGV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8I0P1-1", "uniprot_id": "SPAST_DROME", "id": "Q8I0P1-1", "name": "Spastin", "aln": "--------------------------------------------------------------MVRTKNQSSSSSASSSSTKSPIKSSSGAGSSGGGLGGRQSTHRSSSASNVAAVVAGGSSAAGGGSSSNRRSPGSSPDGDDDTTTTDDLTPTTCSPRSGHHHSYGGYSSSVHKQNLYVVSFPIIFLFNVLRSLIYQLFCIFRYLYGASTKVIYRPHRRDCNIEIVVQNSSKEQQQSLNHPSELNREGDGQEQQLSNQPQRFRPIQPLEMAANRPGGGYSPGPGDPLLAKQKHHHRRAFEYISKALKIDEENE-GHKELAIELYRKGIKELEDGIAVDCWSGRGDVWDRAQRLHDKMQTNLSMARDRLHFLALREQDLQMQRLSLKEKQKEEAQ--SKPQKTREPMLAGMTNEPMKLRVRSSGYGPKATTSAQPTASGRKLTIGSKRPVNLAVANKSQTLPRNLGSKTSVGAVQRQPAKTAATPPAVRRQFSSGRNTPPQRSRTPINNNGPSGSGASTPVVSVKGVEQKLVQLILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFTGLRAPAKGLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLSERSSSEHEASRRLKTEFLVEFDGLPGNPDG---------DRIVVLAATNRPQELDEAALRRFTKRVYVSLPDEQTRELLLNRLLQKQGSPLDTEALRRLAKITDGYSGSDLTALAKDAALEPIRELNVEQVKCLDISAMRAITEQDFHSSLKRIRRSVAPQSLNSYEKWSQDYGDITI-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40328-1", "uniprot_id": "TBP6_YEAST", "id": "P40328-1", "name": "Microtubule severing ATPase YTA6", "aln": "MAHEKFSIPENFTLAQSLQLLYSVVKNQYKNLADLIINSKGNKDTVTYGKIHKNLDTLLVYVNEGLRKIEKTYTLKKGLGNLVVDHPELRSIIEDFQILGQDIRIARRKAETLMAEGNGSPSLSSSSS------------------------------------------VLGLGTGNGLRFPKLWRMGSKRDKLKEADEKEAKINKQADNIRRARKLEE-------------------------EKKLGAKLQYERDLELQREKLIELKVKEKVEFEVAQKLEEERVKREEEERKHREQAEKKRISTLKHERKTNYKSRASLDNFSSSSKSSGKIDNSLIKRRSLDVVRTSGERVRTPVRKSMEAAEIGMAAQLAWSQYQNGANHSKVSNNGSHSNELQIRYKPTPPLKKRYDYKKPTVNRPIIKSPTLNRQNSKSSRNIPTNSKLKASKSNTNKVSRRNEQNLEPSSPVLVSATAVPAESKPMRSKSGTPDKESSASSSLDSRKED----------ILKSVQGVDRNACEQILNEILVTDEKVYWEDIAGLRNAKNSLKEAVVYPFLRPDLFKGLREPVRGMLLFGPPGTGKTMIAKAVATESNSTFFSVSASSLLSKYLGESEKLVRALFYMAKKLSPSIIFIDEIDSMLTARSDNENESSRRIKTELLIQWSSLSSATAQSEDRNNTLDSRVLVLGATNLPWAIDDAARRRFSRKLYIPLPDYETRLYHLKRLMAKQKNSLQDLDYELITEMTEGFSGSDLTSLAKEAAMEPIRDLG-DKLMFADFDKIRGIEIKDFQNALLTIKKSVSSESLQKYEEWSSKFGSNGS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . . . . . :: . . *:.* : * : **** ** :: * :: * **::*.*:* * :*:*******.***::.:.:* :. :.*:.:..::* **::*:.**:*::** :* .*::*****:**:* * .*:::: *:*.*:*:. .. *::*:.*** * :*:*. **: :::*:.** .:* : .*: : * :.. ::.:**:*: *.: *:: *:*.* .: : : ** .:: : :*:.: . : *. :* ", "identical_positions": 84, "similar_positions": 119, "identity": "10.08%" }, { "cls_id": "homologset.agr.SGD:S000005997", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PQQ4-1", "uniprot_id": "PIGC_RAT", "id": "Q5PQQ4-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit C", "aln": "MCAQHVADTSEVKWQKVLYERQPFPDNYVDQRFLEELRKNIYARKYQYWAVVFESSVVIQQLCSVCVFVVIWWYMDEGLLAPQWLFGTGLASSLVGYVLFDLIDGGDGRKKSGRTRWADLKSTLVFITFTYGFSPVLKTLTESVSTDTIYAMSVFMLLGHLIFFDYGANAAIVSSTLSLNMAIFASVCLASRLPRSLHAFIMVTFAIQIFALWPMLQKKLKAYTPRSYVGVTLLFAFSAFGGLLSISGVGAILFALLLFSISCLCPYYLIHLQLFKENIHGPWDEAEIKEDLSRFLS-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CXR4-1", "uniprot_id": "PIGC_MOUSE", "id": "Q9CXR4-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit C", "aln": "MCAQRVTDTPEVKWQKVLYERQPFPDNYVDQRFLEELRKNIYARKYQYWAVVFESSVVIQQLCSVCVFVVIWWYMDEGLLAPQWLFGTGLASSLVGYVLFDLIDGGDGRKKSGRTRWADLKSTLVFITFTYGFSPVLKTLTESVSTDTIYAMAVFMLLGHLIFFDYGANAAIVSSTLSLNMAIFASVCLASRLPRSLHAFIMVTFAIQIFALWPMLQKKLKAYTPRSYVGVTLLFAFSAFGGLLSISAVGAILFALLLFSISCLCPYYLIHLQLFKENIHGPWDEAEIKEDLSRFLS-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92535-1", "uniprot_id": "PIGC_HUMAN", "id": "Q92535-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit C", "aln": "MYAQPVTNTKEVKWQKVLYERQPFPDNYVDRRFLEELRKNIHARKYQYWAVVFESSVVIQQLCSVCVFVVIWWYMDEGLLAPHWLLGTGLASSLIGYVLFDLIDGGEGRKKSGQTRWADLKSALVFITFTYGFSPVLKTLTESVSTDTIYAMSVFMLLGHLIFFDYGANAAIVSSTLSLNMAIFASVCLASRLPRSLHAFIMVTFAIQIFALWPMLQKKLKACTPRSYVGVTLLFAFSAVGGLLSISAVGAVLFALLLMSISCLCPFYLIRLQLFKENIHGPWDEAEIKEDLSRFLS-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2U8U156-1", "uniprot_id": "A0A2U8U156_DROME", "id": "A0A2U8U156-1", "name": "", "aln": "--MVKNGQSKRQPWVKNLYSNREYPDNYTDASFLKDLRTNLHCRIYTFGEAIAGITVLNNQISCITGFLILYQLMLSDSVSPTTILVPSCGITGIGYLCYR------GRSLSWALLGEDSKTLVTVVLFGYLFSPMLHTLTQAISTDTIYTMTFFVLLGNLIFGHYGLDVAMVSKAVSLNAAIFGAICLASRLPTSYHAFVLLVEAAVFFVLYPIMTEAN------WHAGFMLPIFAICCMALYCISRPVLYLYASTTIFINFVCPFIFVWQQQYKFNIHGPWDEAIVEENTEENLDGNLXRQLRFSEQLPPRLGSGDVEEHFTDR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46961-1", "uniprot_id": "GPI2_YEAST", "id": "P46961-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase GPI2 subunit", "aln": "--------MTRSPWKRLLWLKQEYPDNYTDPSFIELRARQKAESNQKSDRKLSEAARAQIRLDFISFYQTILNTSFIYITFTYIYYYGFDPIPPTIFLSFITLIISRTKVDPLLSSFMDVKSSLIITFAMLTLSPVLKSLSKTTASDSIWTLSFWLTL-WYIFVISSTKSKDKPSNLSTNILVALVAVLSSRLSTTIDVFCFLLICIQLNIILPTYLSVTNKVVPIISNIIVYSFLNVALGWIYML-----LIFFASVFYITVLPKWFIYWKINYHKRDN---DLLSTWDARTPILD-----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : *: .: :****.* *:: : : : :: : : : . . :: : : . * *: : . :**:*::*::: ::*:*::::.:: * ** . . .. :* * : *:***. : ..* :: . : : * . . : . : : :: : *. : : : :: . : * : *. ", "identical_positions": 30, "similar_positions": 79, "identity": "9.2%" }, { "cls_id": "homologset.agr.SGD:S000005999", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P19511-1", "uniprot_id": "AT5F1_RAT", "id": "P19511-1", "name": "ATP synthase peripheral stalk subunit b, mitochondrial", "aln": "--MLSRVVLSAAATAAPCLKNAAVLGPGVLQATRVFHTGQPRLAPLPPLPEYGGKVRLGLIPEEFFQFLYPKTGVTGPYVLGTGLSLYFLSKEIYVITPETFSTISVVGLIVYVIKKYGASIGEFIDKLNEEKIAQLEEIKQSSMKQIQDAINREKAQQALVQKRHYLFDVQRNNIALALEVTYRERLHKAYKEVKNRLDYHISVQDMMRRKEGEHMINWVEKHVIQSIS-AQQEKETIAKCIGDLKMLAKKAQAQPIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQQ7-1", "uniprot_id": "AT5F1_MOUSE", "id": "Q9CQQ7-1", "name": "ATP synthase peripheral stalk subunit b, mitochondrial", "aln": "--MLSRVVLSAAATAAPCLKNAAALGPGVLQATRAFHTGQPRLAPLPPLPEYGGKVRLGLIPEEFFQFLYPKTGVTGPYVLGTGLSLYFLSKEIYVITPETFSTISVVGLIVYVIKKYGASFGEFIDKLNEEKIAQLEEVKQSSMKQIQDAIDMEKAQQALVQKRHYLFDVQRNNIALALEVTYRERLHKAYKEVKNRLDYHISVQNMMRRKEEEHMIDWVEKHVVKSIS-VQQEKETIAKCIEDLKLLAKKAQAQPIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24539-1", "uniprot_id": "AT5F1_HUMAN", "id": "P24539-1", "name": "ATP synthase peripheral stalk subunit b, mitochondrial", "aln": "--MLSRVVLSAAATAAPSLKNAAFLGPGVLQATRTFHTGQPHLVPVPPLPEYGGKVRYGLIPEEFFQFLYPKTGVTGPYVLGTGLILYALSKEIYVISAETFTALSVLGVMVYGIKKYGPFVADFADKLNEQKLAQLEEAKQASIQHIQNAIDTEKSQQALVQKRHYLFDVQRNNIAMALEVTYRERLYRVYKEVKNRLDYHISVQNMMRRKEQEHMINWVEKHVVQSIS-TQQEKETIAKCIADLKLLAKKAQAQPVM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q94516-1", "uniprot_id": "AT5F1_DROME", "id": "Q94516-1", "name": "ATP synthase subunit b, mitochondrial", "aln": "--MFSRAAL---LTAQRPLTVAATRSAAAAAAPGGAIERRQR-------PEHPGKVRLGFLPEEWFQFFYNKTGVTGPYTFGVGLITYLCSKEIYVMEHEYYSGLSLGIMAIIAVKKLGPVIAKWADGEIDKIESEWKEGREAELKVLSDAIEAEKKEQWRADGALLLMEAKKENIALQLEAAFRERAMNVYSEVKRRLDYQVECRHVERRLSQKHMVNWITTNVLASIS-PQQEKETLNKCIADLSALALRVKSA---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05626-1", "uniprot_id": "ATPF_YEAST", "id": "P05626-1", "name": "ATP synthase subunit 4, mitochondrial", "aln": "MSMSMGVRGLALRSVSKTLFSQGVRCPSMVIGARYMSSTPEK----QTDPKAKANSIINAIPGN---NILTKTGVLG---TSAAAVIYAISNELYVINDESILLLTFLGFTGLVAKYLAPAYKDFADARMKKVSDVLNASRNKHVEAVKDRIDSVSQLQNVAETTKVLFDVSKETVELESEAFELKQKVELAHEAKAVLDSWVRYEASLRQLEQRQLAKSVISRVQSELGNPKFQEKVLQQSISEIEQLLSKLK-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . :. * . .. .. : *: .: . :* : : **** * ... * *:*:**: * ::. . * .. .: * .: : :: :: :.: *: . * .: *::..::.: : *. :: . *.* ** : . *: . .:: . : ..* .:. : :::.: :.* ::. * : : ", "identical_positions": 29, "similar_positions": 85, "identity": "11.2%" }, { "cls_id": "homologset.agr.SGD:S000006000", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O09167-1", "uniprot_id": "RL21_MOUSE", "id": "O09167-1", "name": "Large ribosomal subunit protein eL21", "aln": "MTNTKGKRRGTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAVGIIVNKQVKGKILAKRINVRIEHIKHSKSRDSFLKRVKENDQKKKEAKEKGTWVQLKRQPAPPREAHFVRTNGKEPELLEPIPYEFMA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46778-1", "uniprot_id": "RL21_HUMAN", "id": "P46778-1", "name": "Large ribosomal subunit protein eL21", "aln": "MTNTKGKRRGTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAVGIVVNKQVKGKILAKRINVRIEHIKHSKSRDSFLKRVKENDQKKKEAKEKGTWVQLKRQPAPPREAHFVRTNGKEPELLEPIPYEFMA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20280-1", "uniprot_id": "RL21_RAT", "id": "P20280-1", "name": "Large ribosomal subunit protein eL21", "aln": "MTNTKGKRRGTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAVGIIVNKQVKGKILAKRINVRIEHIKHSKSRDSFLKRVKENDQKKKEAKEKGTWVQLNGQPAPPREAHFVRTNGKEPELLEPIPYEFMA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZEK2-1", "uniprot_id": "D3ZEK2_RAT", "id": "D3ZEK2-1", "name": "Large ribosomal subunit protein eL21", "aln": "MTNTKGKRRGTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKYYHGKTGRVYNVTQHSVGIIVNKQVKGKILAKRINVRIEHIKHLKSRDSFLKRVKENDQKKKEAKEKGTWVQLKRQPAPPREAHFVRTNGKEPGLLEPSPYGFMA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6A5T5-1", "uniprot_id": "A0A8I6A5T5_RAT", "id": "A0A8I6A5T5-1", "name": "Large ribosomal subunit protein eL21", "aln": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0M392-1", "uniprot_id": "A0ABK0M392_RAT", "id": "A0ABK0M392-1", "name": "Large ribosomal subunit protein eL21", "aln": "MTNTKGKRRGTWYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAVGIIVNKQVKGKIPAKRINVWFEHIKHSKSRDSFLKRVKENDQKKKEAKEKGTWVQLKRQPAPPREAHFVRTNGKEPELLEPSPYEFMA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZQ96-1", "uniprot_id": "D3ZQ96_RAT", "id": "D3ZQ96-1", "name": "Large ribosomal subunit protein eL21", "aln": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9V9M7-1", "uniprot_id": "Q9V9M7_DROME", "id": "Q9V9M7-1", "name": "Large ribosomal subunit protein eL21", "aln": "MTNSKGYRRGTRDMFSRPFRKHGVIPLSTYMRVFKIGDIVDIKGHGAVQKGLPYKAYHGKTGRIFNVTQHAVGVIVNKRVRGKILAKRVNVRIEHIHHSKCREDFLRRVKENERLLKEAKEKGQWVSLKRQPEQPKKAHFVKK-LEEPIALAPIPYEFIA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12672-1", "uniprot_id": "RL21B_YEAST", "id": "Q12672-1", "name": "Large ribosomal subunit protein eL21B", "aln": "MGKSHGYRSRTRYMFQRDFRKHGAVHMSTYLKIYKVGDIVDIKANGSIQKGMPHKFYQGKTGVVYNVTKSSVGVIINKMVGNRYLEKRLNLRVEHIKHSKCRQEFLERVKANAAKRAEAKAQGVAVQLKRQPAQPRESRIVSTEGNVPQTLAPVPYETFI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::: * * :*.* **:**.: : **::::* *******. *: ***:.:* *:*** :***: :**:::** * .: **:*: .** :* *.*: **.:** * *** :* *.*. ** *:::::* . : * * * ", "identical_positions": 62, "similar_positions": 45, "identity": "38.75%" }, { "cls_id": "homologset.agr.SGD:S000006002", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29314-1", "uniprot_id": "RS9_RAT", "id": "P29314-1", "name": "Small ribosomal subunit protein uS4", "aln": "MPVARS-WVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZWN5-1", "uniprot_id": "RS9_MOUSE", "id": "Q6ZWN5-1", "name": "Small ribosomal subunit protein uS4", "aln": "MPVARS-WVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46781-1", "uniprot_id": "RS9_HUMAN", "id": "P46781-1", "name": "Small ribosomal subunit protein uS4", "aln": "MPVARS-WVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZV50-1", "uniprot_id": "D3ZV50_RAT", "id": "D3ZV50-1", "name": "Small ribosomal subunit protein uS4", "aln": "MLVARS-WVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55935-1", "uniprot_id": "RS9_DROME", "id": "P55935-1", "name": "Small ribosomal subunit protein uS4", "aln": "MVNGRIPSVFSKTYVTPRRPYEKARLDQELKIIGEYGLRNKREVWRVKYALAKIRKAARELLTLDEKDEKRLFQGNALLRRLVRIGVLDESRMKLDYVLGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFVVRLDSQKHIDFSLKSPFGGGRPGRVKRKNLKKNQGGGGGAAEEEED----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O13516-1", "uniprot_id": "RS9A_YEAST", "id": "O13516-1", "name": "Small ribosomal subunit protein uS4A", "aln": "MPRAPR--TYSKTYSTPKRPYESSRLDAELKLAGEFGLKNKKEIYRISFQLSKIRRAARDLLTRDEKDPKRLFEGNALIRRLVRVGVLSEDKKKLDYVLALKVEDFLERRLQTQVYKLGLAKSVHHARVLITQRHIAVGKQIVNIPSFMVRLDSEKHIDFAPTSPFGGARPGRVARRNAARKAEASGEAADEADEADEE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . *** **:**:*.:*** ***: **:**:**:*::*:.: *:***:***:*** **** :***:****:*****: **.*.: ****:*.**:************:** ****:***:*** **** * **:******:* ***.*****: **:**.***** *:* : ..* . :* .: ", "identical_positions": 118, "similar_positions": 45, "identity": "59.3%" }, { "cls_id": "homologset.agr.SGD:S000006003", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LW16-1", "uniprot_id": "F1LW16_RAT", "id": "F1LW16-1", "name": "", "aln": "MGYQACPVFLLILDRLFILLDTGTTPVTRKAAAQQLGEVVKLHPHELNNLLSKVLIYLRSANWDTRIAAGQAVEAIVKNVPEWNPVPRTK-----------------QEPT-ECSMEDSSTTDR--LNFDRFDICRLLQHGASLLGSAGAEFEVQDEK----SGEVDP--KERIARQRKLLQKK--LGLNMGEAIGMSTEELFNDEDLDYTPTSAALVNK----------QSTLQAAELIDSEFRAG------MSNRQKNKAKRMAKLFAK---------------QRSRDAVETNEKSNDSTDGEPEEKRRKV-ANVVINQTASDAKVLIDNVPE---SSSFIEETNEWPLESFCEELCNDLFNPSWEVRHGAGTGLREILKAHGKSGGKMGDSTLEEMIQQHQEWLEDLVIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVVLKHMNETGVHKTVDVLLKLLT---------QEQWEVRHGGLLGIKYALAVRQDVINTL--LPKVLTRIIEGLQDLDDDVRAVAAASLVPVVESLVYLQ-TQKVPSIINTLWDSLLELDD-LTASTNSIMTLLSSMLTYPQVQQCSIQQSLT--------VLVPRVWPFLHHTISSVRRAALETLFTLLSTQ-------DQN----------------SSSWLIPILSDMLRHIFQFCVLESSQEILDLIHKVWMELLSKASVQYVVAAACPWMGAWLCLMMQPSHLPID---LNMLLEVK---------ARTKEKTGGKVRQG--QMQSKEVLQEYIAGADTIMEDPATRDFVVMR--ARMMAAKLLGALCCCICDPG--VNMVNQEIKPAESLGQLLLFHLNSKSALQRISAALVICEWAALQKECKAVTLAVQPRLLDILSEHLY-------YDEIAVPFTRMQNECKQFISSLADA-----------HIEVGNRVNN--NVLTIDQANDLVTTLFNEVTSTFD--LNPQVLQQLDSKRHQVQMTVAETNQEWQVLQLRVHTFAACAVVSLQQLPEKLNPIIKPLMETIKKEENTLVQNYAAQYIAKLLQQCTTRTPCPNS-KVIKNLCSSLCVDPYLTPCVTCPVPTQSG--QENSKGSNSEKDGMHHTVTKHRGIITLYRH----QKAAFAITSRRGP-IPKAIKAQIA-DLPAGSSGNILVELDEGQKPYLVQRRGAEFALTTVVKHFGAEMALKLPHLWDAMVGPLKTMIDLNNFDGKSLLERGDAPAQELVNSLQVFETAAASMDSELHP-LLVQHLPHLYMCLQYPSTAVRHMAARCVGVMSKIATMETMNIFLEKVLPWLGAIDDNVKQEGAIEALACVMEQLDVGIVPYIVLLVVPVLGRMSDQTDSVRFMATQCFATLIRLMPLEAGIPDPPNMSEELIQLKAKERHFLEQLLDGKKLENYKIPVPINAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHCQRAQEYARSKLAECMPLPSLVVCPPTLTGHWVDEVGKFCSR-EYLNPLHYTGPPTERIRLQHQV-KRHNLIVASYDVVRNDIDFFRNIKFNYCILDEGHVIKNGKTKLSKAVKQLTANYRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGVLAMDALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCTLSPLQVQLYEDFAKSRAKCDVDETVSSAALSEETEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEFKNTTEKLAVQNSSLHDIQHAPKLSALKQLLLDCGLG-------NGTSSESGTESVVAQHRILIFCQLKSMLDIVEHDLLKPHLPSVTYLRLDGSIPPGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMNIANTVISQENSSLQSMGTDQLLDLFTLD------------KDGKAEKAD----SSTSGKASMKSVLENLSDLWDAEQYDSEYNLETFMRSLE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9QAE3-1", "uniprot_id": "E9QAE3_MOUSE", "id": "E9QAE3-1", "name": "", "aln": "-------MAVSRLDRLFILLDTGTTPVTRKAAAQQLGEVVKLHPHELNNLLSKVLIYLRSTNWDTRIAAGQAVEAIVKNVPEWNPVPRTK-----------------QEPT-ESSMEDSSTTDR--LNFDRFDICRLLQHGASLLGSAGAEFEVQDEK----SGEVDP--KERIARQRKLLQKK--LGLNMGEAIGMSTEELFNDEDLDYTPTSAALVNK----------QSTLQAAELIDSEFRAG------MSNRQKNKAKRMAKLFAK---------------QRSRDAVETNEKSNDSTDGEPEEKRRKV-ANVVINQTASDSKVLIDNVPE---SSSLIEETNEWPLESFCEELCNDLFNPSWEVRHGAGTGLREILKAHGKSGGKMGDSTLEEMIQQHQEWLEDLVIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVVLKHMNETGVHKTVDVLLKLLT---------QEQWEVRHGGLLGIKYALAVRQDVINTL--LPKVLTRIIEGLQDLDDDVRAVAAASLVPVVESLVYLQ-TQKVPSIINTLWDSLLELDD-LTASTNSIMTLLSSMLTYPQVQQCSIQQSLT--------VLVPRVWPFLHHTISSVRRAALETLFTLLSTQ-------DEN----------------SSSWLIPILSDMLRHIFQFCVLESSQEILDLIHKVWMELLSKASVQYLVAAACPWMSAWLCLMMQPSHLPID---LNMLLEVK---------ARAKEKTGGKVRQG--QIQNKEVLQEYIAGADTIMEDPATRDFVVMR--ARMMAAKLLGALCCYICDPS--VNMVNQEIKPADSLGQLLLFYLNSKSALQRISVALVICEWAALQKECKAVTLAVQPRLLDILSEHLY-------YDEIAVPFTRMQNECKQFISSLADA-----------HIEVGNRVNN--NVLTIDQANDLVTTIFNEVTSTFD--LNPQVLQQLDSKRHQVQMTVAETNQEWQVLQLRVHTFAACAVVSLQQLPEKLNPIIKPLMETIKKEENTLVQNYAAQYIAKLLQQCTTRTPCPNS-KVIKNLCSSLCVDPYLTPCVTCPVPTQSG--QENSKGSNSEKDGMHHTVTKHRGIITLYRH----QKAAFAITSRRGP-IPKAIKAQIA-DLPAGSSGTILVELDEGQKPYLVQRRGAEFALTTIVKHFGAEMAVKLPHLWDAMVGPLKSMIDLNNFDGKSLLERGDVPAQELVNSLQVFEIAAASMDSALHP-LLVQHLPHLYMCLQYPSTAVRHMAARCIGVMSKIATMETMNIFLEKVLPWLGAIDDNVKQEGAIEALACVMEQLDVGIVPYIVLLVVPVLGRMSDQTDSVRFMATQCFATLIRLMPLEAGIPDPPNMSEELIQLKAKERHFLEQLLDGKKLENYKIPVPINAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHCQRAQEYARSKLAECMPLPSLVVCPPTLTGHWVDEVGKFCSR-EYLNPLHYTGPPTERIRLQHQV-KRHNLIVASYDVVRNDIDFFRNIKFNYCILDEGHVIKNGKTKLSKAVKQLTANYRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGVLAMDALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCTLSPLQVQLYEDFAKSRAKCDVDETVSSAALSEETEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEFKSTTEKLTVQNSSLHDIQHAPKLSALKQLLLDCGLG-------NGSSTESGTESVVAQHRILIFCQLKSMLDIVEHDLLKPHLPSVTYLRLDGSIPPGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMNIANTVISQENSSLQSMGTDQLLDLFTLD------------KDGKAEKAD----SSTSGKASMKSVLENLSDLWDAEQYDSEYNLETFMRSLE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14981-1", "uniprot_id": "BTAF1_HUMAN", "id": "O14981-1", "name": "TATA-binding protein-associated factor 172", "aln": "-------MAVSRLDRLFILLDTGTTPVTRKAAAQQLGEVVKLHPHELNNLLSKVLIYLRSANWDTRIAAGQAVEAIVKNVPEWNPVPRTR-----------------QEPTSESSMEDSPTTER--LNFDRFDICRLLQHGASLLGSAGAEFEVQDEK----SGEVDP--KERIARQRKLLQKK--LGLNMGEAIGMSTEELFNDEDLDYTPTSASFVNK----------QPTLQAAELIDSEFRAG------MSNRQKNKAKRMAKLFAK---------------QRSRDAVETNEKSNDSTDGEPEEKRRKI-ANVVINQSANDSKVLIDNIPD---SSSLIEETNEWPLESFCEELCNDLFNPSWEVRHGAGTGLREILKAHGKSGGKMGDSTLEEMIQQHQEWLEDLVIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVVLKHMNETGVHKTVDVLLKLLT---------QEQWEVRHGGLLGIKYALAVRQDVINTL--LPKVLTRIIEGLQDLDDDVRAVAAASLVPVVESLVYLQ-TQKVPFIINTLWDALLELDD-LTASTNSIMTLLSSLLTYPQVQQCSIQQSLT--------VLVPRVWPFLHHTISSVRRAALETLFTLLSTQ-------DQN----------------SSSWLIPILPDMLRHIFQFCVLESSQEILDLIHKVWMELLSKASVQYVVAAACPWMGAWLCLMMQPSHLPID---LNMLLEVK---------ARAKEKTGGKVRQG--QSQNKEVLQEYIAGADTIMEDPATRDFVVMR--ARMMAAKLLGALCCCICDPG--VNVVTQEIKPAESLGQLLLFHLNSKSALQRISVALVICEWAALQKECKAVTLAVQPRLLDILSEHLY-------YDEIAVPFTRMQNECKQLISSLADV-----------HIEVGNRVNN--NVLTIDQASDLVTTVFNEATSSFD--LNPQVLQQLDSKRQQVQMTVTETNQEWQVLQLRVHTFAACAVVSLQQLPEKLNPIIKPLMETIKKEENTLVQNYAAQCIAKLLQQCTTRTPCPNS-KIIKNLCSSLCVDPYLTPCVTCPVPTQSG--QENSKGSTSEKDGMHHTVTKHRGIITLYRH----QKAAFAITSRRGP-TPKAVKAQIA-DLPAGSSGNILVELDEAQKPYLVQRRGAEFALTTIVKHFGGEMAVKLPHLWDAMVGPLRNTIDINNFDGKSLLDKGDSPAQELVNSLQVFETAAASMDSELHP-LLVQHLPHLYMCLQYPSTAVRHMAARCVGVMSKIATMETMNIFLEKVLPWLGAIDDSVKQEGAIEALACVMEQLDVGIVPYIVLLVVPVLGRMSDQTDSVRFMATQCFATLIRLMPLEAGIPDPPNMSAELIQLKAKERHFLEQLLDGKKLENYKIPVPINAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHCHRAQEYARSKLAECMPLPSLVVCPPTLTGHWVDEVGKFCSR-EYLNPLHYTGPPTERIRLQHQV-KRHNLIVASYDVVRNDIDFFRNIKFNYCILDEGHVIKNGKTKLSKAVKQLTANYRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGVLAMDALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCTLSPLQVQLYEDFAKSRAKCDVDETVSSATLSEETEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEFKTTAEKLAVQNSSLHDIQHAPKLSALKQLLLDCGLG-------NGSTSESGTESVVAQHRILIFCQLKSMLDIVEHDLLKPHLPSVTYLRLDGSIPPGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMNIANTVISQENSSLQSMGTDQLLDLFTLD------------KDGKAEKAD----TSTSGKASMKSILENLSDLWDQEQYDSEYSLENFMHSLK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BGW0-1", "uniprot_id": "A0A8M2BGW0_DANRE", "id": "A0A8M2BGW0-1", "name": "", "aln": "-------MAVSRLERLFILLDTGTTPVTRKAAAQQLGDVVKLHPHELNNLLSKVLTYLRSPNWDTRIAAGQAVEAIVKNIPEWNPSPKPK-----------------DEVCAEDLSPEDVSTDR--LSFYRFDISRLLKHGASLLGSAGAEFELQDDK----SGETDP--KERLARQRKQLQKK--LGLDMGAAIGMDTEELFNDEDLEDACASSTNRTQPGKSLGCHFSRNHLPAAELIDSEFRPG------MSNRQKNKAKRMAKLVAK---------------QRSRD-VDSNEKSNDSFEGEPEEKRRKT-TNVVIEQPANDSKVLIDNVPD---NSSLFEETQEWPLESFCDELCNDLFNPSWEIRHGAGTGLREVLKCHGAGGGKTVGSTAEQMERQHQEWLEDLVIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVALRHMENSGVAMTVDILLKLLT---------EDQWEVRHGGLLGIKYALAVRQDLIAEL--LPRVLPAITEGLRDLDDDVRAVAAAALIPVVDGLVQLQ-PAKVPFIVDTLWNALLELDD-LTASTNSIMTLLSSLLTYPQVRQCSTQQSLT--------VLVPRVWPFLRHTIASVRRAALDTLFTLLSKA-------DQS----------------CAVWLNPIMQDMLRHIFQSCILESNQEILELIQKVWRELLRQAPQQYVVAASCPWMGAWLCLMMQAPHIPID---PNMLLEVK---------ARFKEKAAGKARQG--SVPVKETVQEYIGGAETVTEEPATRDYVVTR--ARLMAAKLLGALCSCICDPR--LNSSSLELRPAESLAQLLLFHLNSKSALQRIAVSMVICEWAGLQKECELLSSVVQPRLLVILSEQLY-------YDEIAIPFTRMQNECKQLIALLADA-----------HIDVRERINS--TVFTIDQANELVTTIFSESTSTLN--LKSRQFQPLDSKRIQAQSTVCETSAEWQQLQLRVHTFTACAVVGLGMLPDKLNPVVRPLMEAARREENSLVQGCAASNIAHLLQLCAARSPCPNA-KIVKNLCSSVCVDPMLTPSAACPVPPASTPIQESSKASVAEKDAMHHMVNKTKGIITLYRH----QKAAFAITSKRGP-TPKTPKSNTNNDLPVG--GSISTETDESKKPCLIQRRGAEFCLMTVARHFSKELTKTLPYLWESMTGPLRNALDAQEFDSSQLLKQGDSVAQDLVNSLQVLEVTAGAMSQELIP-LLMEQLPLLCTCLQHPYTAVRHMAARCVGVLSKIATMETMNVFLEQVLPWLGAIDDNTKQEGAIEALACVMEQLDVDIVPYIVLLVVPVLGRMSDPCDSVRFMATQCFATLIRLLPLEAGIPDPPSMSEDLIRQKARERHFLEQLLDGRKLENYKIPVPIKAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHFLRAQEYTRTKAPDSCPLPSIVVCPPTLTGHWVDEVGKFCSK-EFLNPLHYTGPPTERARLQHQV-KKHNLIVASYDVVRNDVEFFRDIKFNYCILDEGHVIKNGKTKLSKAIKQLTANYRLILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDAKSSSREQEAGVLAMEALHRQVLPFLLRRMKDDVLQDLPPKIIQDYYCNLSPLQVQLYEDFAKSRAKVNVDDVISTASTQEDEEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEYKHITEQLSTQHSSLRDIQHAPKLSALKQLLLDCGLG-------SAGASDSGTEAVVAQHRVLIFCQLKSMLDIVEQDLLKPQLPGVTYLRLDGSVQAGLRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMTIANTVISQENASLQSMGTEQLLNLFTLD------------KDDKAEKCDG--SSSSSGKSSMKSVLDGLGDLWDQQQYENEYDLGTFMHSLK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VF02-1", "uniprot_id": "Q9VF02_DROME", "id": "Q9VF02-1", "name": "", "aln": "--------MTSRLDRLFILLETGSTAATRQAAAKQIGEVQKLYPHELHALLNRLVGYLHSTSWETRIAAAQTVEAILKQVPPWQPEFQVLPKKERCATNTATAAAAAEEDSCQSSGSNSTTASERLLSFDEFDLQQILHKGARLIGSEGNEFDVQEEQPASGGGEEDRSLASRLSRQRAVLNDK--LGLTTAAKLGVNLTDMITDEDVALNRSGSTYNVN----------AEKLPVEHLLNIKTAANGSGQAPLSCREMNRAKRKARQNTSGCSVTAVTPTCSRRNSNSNHSTGSNHSSNGTTGAAIEEPEKKK-LKSTDRQEIFYS--LNAAVPD---ATGTWVDAVSWPLENFCSRLFIDLFHAKWEVRHGAATALRELINQHAQGAGKAVLQTREQMDEAHSRWLEDAALRLLCVLCLDRFGDFVSDQVVAPVRETCAQVLGTLVKEMEASKVQRIVNILLQLIQH--------KNEWDVRHGGLLGLKYVFVVREELLPIY--LPQSISNILIGLLDAVDDVGAVAAATLIPVSSWLPKLLNPAQVSSIVKMLWDLLLDQDE-LTSACNSFMGLLAAILCLPNAARWVEMEPMA--------ILVPRLWPFLSHSTSSVRRSTLKTLMTLTSADRVKSEPKDENQVKEEADKEEMKLNFGVSDWKWELLQQALRHIYQRILVEPQADIQALARQVWSNLIQHADLGALLHAACPFVSSWICLSMQPPRLAFD---AGVLIRAGGDVSTPGSTSRKRTPRIGDELGGNILAQSNASLKLYLGGSEATPLD--VRDANFMR--ARISSSRALGALSHYLVQPAPGVVYTPQTESPTDCYTKVLLGHLNAHSAVQRIVCGLIIAFWALEDEPVRPGPPNLQEKLHQCVSEYVY-------YDEVAISLTRLLQEAQDFIATLKQN-----------KIPINDFNNA--KILTLDQIEAVATTLS-ENLRSYP--LKPKVLDMLEERRRSLQASYQQTTSEQSAYHVSAQAALAGAICALHCLPDKLNPVVKPLMESIKREQCLQLQQLSAEFLVHLMDQVCDRNPSPNS-KILNNLCTLLRSDPEFTPKLVMPLETLKQTPVSSEVINNCVYYGILTLALQQTVTTTNTRSGAGGATTPTATTAPRGPGRPPTGEILSATNATAHIELKAQQAKEAEAKQCRIQRLGAACAIEKLCRIFGEQIIEKVAVFQHLMFGKVEQFVKEAYDWRLGSLLPDLGVCNELVSSMQLIETAAPHLHVALHP-QMFALLPSLGFIVCHPLKAVRHMAARCIAVLAEIDACQTMQFVVHDLLPLLGKIEQLIERQGAIEAIERVVSRLQIKVVPYIVLLVVPLLGAMSDPDESVRLLSTHCFANLVQLMPLDG--KTEQLKSDPLQARKTRDREFLDYLFNPKSIPNYKVPVPISVELRCYQQAGINWLWFLNKYNLHGILCDDMGLGKTLQTICILAGDHMHR-------QTANLANLPSLVICPPTLTGHWVYEVEKFLDQGSVLRPLHYYGFPVGREKLRSDIGTKCNLVVASYDTVRKDIDFFSGIHFNYCVLDEGHIIKNGKTKSSKAIKRLKANHRLILSGTPIQNNVLELWSLFDFLMPGFLGTEKQFVQRFSRPILSSRDAKSSAKEQEAGVLAMEALHRQVLPFLLRRVKEDVLKDLPPKITQDLLCELSPLQLRLYEDFSNKHLKDCLDKLGDSSSASMVTEN--LSAKTHIFQALRYLQNVCNHPKLVLR-QSEELTKVTSQLALSNSSLDDIEHSAKLPALKQLLLDCGIG-------VQTES-------VSQHRALIFCQLKAMLDIVEQDLLRRHLPSVTYLRLDGSVPASQRQDIVNNFNSDPSIDVLLLTTMVGGLGLNLTGADTVIFVEHDWNPMKDLQAMDRAHRIGQKKVVNVYRLITRNSLEEKIMGLQKFKILTANTVVSAENASLQTMGTSQIFDLFNGG------------KDKGAESGSSAVQGTASGGMSMNTIIENLPELWSEHQYEEEYDLGNFVQALKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32333-1", "uniprot_id": "BTAF1_YEAST", "id": "P32333-1", "name": "TATA-binding protein-associated factor MOT1", "aln": "-----MTSRVSRLDRQVILIETGSTQVVRNMAADQMGDLAKQHPEDILSLLSRVYPFLLVKKWETRVTAARAVGGIVAHAPSWDPN---------------------ESDLVGGTNEGSPLDNAQVKLEHEMKIKLEEATQNNQLNLLQEDHHLSSLS----DWKLNEILKSGKVLLASSMNDYNVLGKADDNIRKQAKTDDIKQETSMLNASDKANENK---------SNANKKSARMLAMARRKK-------KMSAKNTPKHPVDITES---------------SVSKTLLNGKNMTNSAASLATSPTSNQLNPKLEITEQADESKLMIESTVRPLLEQHEIVAGLVWQFQGIYELLLDNLMSENWEIRHGAALGLRELVKKHAYGVSRVKGNTREENNLRNSRSLEDLASRLLTVFALDRFGDYVYDTVVAPVRESVAQTLAALLIHLDSTLSIKIFNCLEQLVLQDPLQTGLPNKIWEATHGGLLGIRYFVSIKTNFLFAHGLLENVVRIVLYGLNQSDDDVQSVAASILTPITSEFVKLN-NSTIEILVTTIWSLLARLDDDISSSVGSIMDLLAKLCDHQEVLDILKNKALEHPSEWSFKSLVPKLYPFLRHSISSVRRAVLNLLIAFLSIK-------DDS----------------TKNWLN---GKVFRLVFQNILLEQNPELLQLSFDVYVALLEHYKVKHTEKTLDHVFSKHLQPILHLLNTPVGEKGKNYAMESQYILK-----PSQHYQLHPEKKRSISETTTDSDIPIPKNNEHINIDAPMIAGDITLLGLDVILNTRIMGAKAFALTLSM--FQDSTLQSFFTNVLVRCLELPFSTPRMLAGIIVSQFCSSWLQKHPEGEKLPSFVSEIFSPVMNKQLLNRDEFPVFRELVPSLKALRTQCQSLLATFVDVGMLPQYKLPNVAIVVQGETEAGPHAFGVETAEKVYGEYYDKMFKSMNNSYKLLAKKPLEDSKHRVLMAINSAKESAKLRTGSILANYASSILLFDGLPLKLNPIIRSLMDSVKEERNEKLQTMAGESVVHLIQQLLENNKVNVSGKIVKNLCGFLCVDTSEVPDFSVNAEYKEK---------------ILTLIKE-----------------------------------------SNSIAAQDDINLAKMSEEAQLKRKGGLITLKILFEVLGPSILQKLPQLRSILFDSLSDHENEEAS------KVDNEQGQKIVDSFGVLRALFPFMSDSLRSSEVFTRFPVLLTFLRSNLSVFRYSAARTFADLAKISSVEVMAYTIREILPLMNSAGSLSDRQGSTELIYHLSLSMETDVLPYVIFLIVPLLGRMSDSNEDVRNLATTTFASIIKLVPLEAGIADPKGLPEELVASRERERDFIQQMMDPSKAKPFKLPIAIKATLRKYQQDGVNWLAFLNKYHLHGILCDDMGLGKTLQTICIIASDQYLRKEDYEKTRSVESRALPSLIICPPSLTGHWENEFDQYAPF---LKVVVYAGGPTVRLTLRPQL-SDADIIVTSYDVARNDLAVLNKTEYNYCVLDEGHIIKNSQSKLAKAVKEITANHRLILTGTPIQNNVLELWSLFDFLMPGFLGTEKMFQERFAKPIAASRNSKTSSKEQEAGVLALEALHKQVLPFMLRRLKEDVLSDLPPKIIQDYYCELGDLQKQLYMDFTKKQKNVVEKDIENSEIAD---------GKQHIFQALQYMRKLCNHPALVLSPNHPQLAQVQDYLKQTGLDLHDIINAPKLSALRTLLFECGIGEEDIDKKASQDQNFPIQNVISQHRALIFCQLKDMLDMVENDLFKKYMPSVTYMRLDGSIDPRDRQKVVRKFNEDPSIDCLLLTTKVGGLGLNLTGADTVIFVEHDWNPMNDLQAMDRAHRIGQKKVVNVYRIITKGTLEEKIMGLQKFKMNIASTVVNQQNSGLASMDTHQLLDLFDPDNVTSQDNEEKNNGDSQAAKGMEDIANETGLTGKAKEALGELKELWDPSQYEEEYNLDTFIKTLR-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:* .**::**:* ..*: **.*:*:: * :*.:: **.:: :* .*:**::*.::* .*: : * *:* :. . . .:.: :. :..:.. . . : : . ::. ** : :.:* :. : : .:: . * .*: . . . *. :. :*.: . .: : : : : * ::.: . * :*: .**:****. .***::: *. . .: .* *: :.. *** . *** *:.******:* * *******: **.*.. : .:: : .: * :*: :. *:. ******::* . :: :.: * . : : ** : *** :***: * *: . : * : :: :*. * *: :::: .*:* **: : :. :.: ***:::*** *: :****:.*. *::: * *:. * . :* ::* ::* . :: * .*: *: : : .. : :: . ... . :. . : . . . : . . . : :: :** . : . . :: : * :.: : * . . . * . . . :. : :.: : : *:. .:. : :.:.::: : : * : : : :: . : : : : . *:. : : .:. . . : * :: : ** ****:::.**:: :.*. :* :.. :.:*:: .. : *:::*** : *. .* . : : . : ::* *. : : . :. .: .:. : : . : . . :.:*.*: ::. : * . :. :* * : ...*: *** .. :::* : :.* :..:** :. . .::*: * : : :: ::**:::*:**:** *** :.** ::* **.:::*:**:. . * : ::*.*:: ::: . :*:*:.*.. ** *** *:*** *****:****************:***:*.*: * : : ***:::***:***** *. :: *. : * * *. * *: :: . :::*:***..*:*: .: .:***:*****:***.::* :**:*.:.**:*:**:**************************: * *:.:** :**::::*::********::***:*****:***:*:***.****** ** * *. ** :** **::.: : .. .: . .. *:****:*::::**** *** : : . * .* ** ::.**.**: **::**:* ::*** ******* ***:**:**:: :*.***:*****: . *:.:* .**.***** ***** **************:*********.**************:******:**:.:************: *.**:. :*:.* :*.* *:::** . * * . :. . : : * :**. **:.**.* .*:::*. ", "identical_positions": 488, "similar_positions": 557, "identity": "23.95%" }, { "cls_id": "homologset.agr.SGD:S000006004", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AEJ0-1", "uniprot_id": "A0A8I6AEJ0_RAT", "id": "A0A8I6AEJ0-1", "name": "", "aln": "--------MSRRGPQPRRGAFGGWGGDSAPVASELRAARSRSQKLPQRSHGPKDFLPDGSEAQAERLRLCRQELWQLLAEER-VERLGSLVAAEWRPEEGFVELTSPAGKFWQTMGYSE-EGRQRLHPEEALYLLECGSIQLFY-------------QDLPLSIQEAYQLLLTEDTLS-FLQYQVFSHLKRLGYVVRRFQL-----SSVVSPYERQLNLDGYAQCLEDGSGKRKRSSSC-RSVNKKAKALQNSLPPVSLADSSPPACDQSSPYPEEKPRDSSPEQGSELPMQFLGSPEPCPDPGREDAGCDQESDKIENGAKGTPKPRWNFERISFPNMASDSRHTLLPAPAPELLPVNVIGRGTDAESWCQKLNQRREKLSRRDREQQAEVRQFREDVNADPEVQGCSTWQEYKELLRRRQMQRSQPRPPHLWGQSVTPLLNPDTADSPAAVLQRISVLQTTHLADGGYRLLEKSGGLEISFDVYQADAVATFRKNSPGKPYVRMCISGFDEPVPDLCSLKRLTYQSGDVPLIFALVDHGDISFYSFRDFTLPQDLGH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C2A2-1", "uniprot_id": "SEN54_MOUSE", "id": "Q8C2A2-1", "name": "tRNA-splicing endonuclease subunit Sen54", "aln": "--------ME---PEPEPGSVEVPAG-RVLSASELRAARSRSQKLPQRSHGPKDFLPDGSEAQAERLRLCRQELWQLLAEER-VERLGSLVAAEWKPEEGFVELTSPAGKFWQTMGYSE-EGRQRLHPEEALYLLECGSIQLFY-------------QDLPLSIQEAYQLLLTEDTLS-FLQYQVFSHLKRLGYVVRRFQL-----SSVVSPYERQLNLDGYAQCLEDGSGKRKRSSSC-RSVNKKPKVLQNSLPPVSLAASSSPACDQSSQYPEEKSQDSSPRQGSELPLQFLGSSEPCSDLAREDVGCDRESHKIENGAKGTPKLRWNFEQISFPNMASDSRHTFLPAPAPELLPANVIGRGTDAESWCQKLNQRREKLSRRDREQQAVVQQFREDVNADPEVRGCSSWQEYKELLQRRQTQKSQPRPPHLWGQSVTPLLDPDKADCPAAVLQHISVLQTTHLADGGYRLLEKSGGLQISFDVYQADAVATFRKNSPGKPYVRMCISGFDDPVPDLCSLKCLTYQSGDVPLIFALVDHGDISFYSFRDFTLPRDLGH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z6J9-1", "uniprot_id": "SEN54_HUMAN", "id": "Q7Z6J9-1", "name": "tRNA-splicing endonuclease subunit Sen54", "aln": "--------ME---PEPEPAAVEVPAG-RVLSARELFAARSRSQKLPQRSHGPKDFLPDGSAAQAERLRRCREELWQLLAEQR-VERLGSLVAAEWRPEEGFVELKSPAGKFWQTMGFSE-QGRQRLHPEEALYLLECGSIHLFH-------------QDLPLSIQEAYQLLLTDHTVT-FLQYQVFSHLKRLGYVVRRFQP-----SSVLSPYERQLNLDASVQHLEDGDGKRKRSSSSPRSINKKAKALDNSLQPKSLAASSPPPCSQPSQCPEEKPQESSPMKGPGGPFQLLGSLGPSPGPAREGVGCSWESGRAENGVTGAGKRRWNFEQISFPNMASDSRHTLLRAPAPELLPANVAGRETDAESWCQKLNQRKEKLSRREREHHAEAAQFQEDVNADPEVQRCSSWREYKELLQRRQVQRSQRRAPHLWGQPVTPLLSPGQASSPAVVLQHISVLQTTHLPDGGARLLEKSGGLEIIFDVYQADAVATFRKNNPGKPYARMCISGFDEPVPDLCSLKRLSYQSGDVPLIFALVDHGDISFYSFRDFTLPQDVGH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VTV4-1", "uniprot_id": "Q9VTV4_DROME", "id": "Q9VTV4-1", "name": "", "aln": "--------MDT--KTQDSEYVEIHPKNSYLSAQELIAHRHTEFEPP--SGGLKRTKNEGTAAEVEELKRAQEYLRAQLSVPR-IERLGGRALAIWNEEQQVAEVKRKDGKFEN-FGYSE-QGKLYLEYYEAMFLLEVGRLQLEY-------------CGLVVSIEQAYVLLLGELESERYTNYLVYSALSRSGYIVVKHVP-----PKEIP--QEVTSADCIWALLKEKVGN----------------------------------------LPVPDHIKTSP-------------IYPIAEKRMEDLKELITSQKAED-----------------PNIVVDPIDLKFGQ-----------RKRMAVEKPIEEPASKKEKFSTTGR-------------SLVDQLKGEFAYAKFEEIFEKFDLVQLESQ-------------------------------------DYTKDELDTPSALKIIFDLHLHN--RGFKKSAPNAPNFNVIILPSQVAFPTHDKISKIKHLLTAPLLVISVSESKQIQAFLYYIS--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02825-1", "uniprot_id": "SEN54_YEAST", "id": "Q02825-1", "name": "tRNA-splicing endonuclease subunit SEN54", "aln": "MQFAGKKTDQVTTSNPGFEEEEEEEEELQQDWSQLASLVSKNAALSLPKRGEKDYEPDGTNLQDLLLYNASKAMFDTISDSIRGTTVKSEVRGYYVPHKHQAVLLKPKGSFMQTMGRADSTGELWLDFHEFVYLAERGTILPYYRLEAGSNKSSKHETEILLSMEDLYSLFSSQQEMD---QYFVFAHLKRLGFILKPSNQEAAVKTSFFPLKKQRSNLQAITWRLLSLFKIQELSLFS--------------------------GFFYSKWNFFFRKYTTSPQLYQGLNRLVRSVAVPKNKKELLDAQSDREFQKVKDIP---------------LTFKVWKPHSNFKKRDPGLPDFQVFVYNKNDD--LQHFPTYKELRSMFSSLDYKFEFLSEIEDDDDWETNSYVEDIPRKEYIHKRSAKSQTEKS-----------------------------------ESSMKASFQKKTAQSSTKKKRKAYPPHIQQNRRLKTGYRSFIIAIMDNGLISFVKMSEADFGSESVWYTPNTQKKVDQRWKKH-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* : . . . * * :*: : * . : : :: : . . . : .: . : *.* : :* :: *. *. * ::* * * : : : :*::: * *: : :* *:: *.* *::: .. .. :. . : * . :** * . : :: .: . : : :. :* * . : . :* :.: . : . ::. . . . :: . * : . .:. . . : . ", "identical_positions": 30, "similar_positions": 98, "identity": "5.37%" }, { "cls_id": "homologset.agr.SGD:S000006005", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PB44-1", "uniprot_id": "PTN23_MOUSE", "id": "Q6PB44-1", "name": "Tyrosine-protein phosphatase non-receptor type 23", "aln": "MEAVPRMPMIWLDLKEAGDFHFQSAVKKFVLKNYGEN---PEAYNEELKKLELLRQNAIRVARDFEGCSVLRKYLGQLHYLQSRVPMGSGQEAAVAVTWTEIFSGKSV----SHEDIKYEQACILYNLGALHSMLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAFSVD--MSRQILTLNVNLMLGQAQECLLEKSMLDNRKS---FLVARISAQVVDYYKEACRALEN-----PDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVAYFQSALDKLNEAIKLAKGQPD--TVQDALRFAMDVIGGKYNSAKKDNDFIYHEAVPALDTLQPVKGAPLVKP------LPVNPTDPAVTGPDIFAKLVPMAAHEASSLYSEEKAKLLREMLAKIEDKNEVLDQFMDSMQLDPETVDNLDAYNHIPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELQEQKLQETLGQAGAGPGPSVAKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVGNLRLLSGPLDQVRAALPTPALTPEDKAVLQNLKRILAKVQEMRDQRVSLEQQLRELIQKDDITASLVTT---DHSEMKKLFEEQLKKYDQLKVYLEQNLAAQDNVLRALTEANVQYAAVRRVLSELD------QKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVATLLERAQSICRAQEAARQQ-----------LLDRELKKKAPPPRPTAPKPLLSRREEGEAVEAGDTPEELRSLPPDMMVGPRLPDPFLG-TTAPLHFSPGPFPSSTGPATHYLSGPLPPGTYSGPTQLMQPRA----AVPMAP--------------------ATVLYPAPAYTSELGLVPRSSPQHGIVSSPYAGVGPPQPVVGLPSAPPPQLSGPELAMTVRPATTTVDSVQAPISSHTAPRPNPTPALPQPCFPVPQPVPQSVPQPQPLPVPYTYSIGTKQPLPAPYTYS--------IGTKQHLTGPLPQHQFPPGIPTGFPVPRTGPQAQAQPQPQPQPQPQPQPQPQPQPQPQSQSQPQPQPQPQPQRPAFGPQPTQQPLPFQHPHLFPSQAPGILPPPPPTPYHFTPQPGVLGQPPPTLHTQLYPGPSQDPLPPHSGALPFPSPGPPHP-HPTLAYGPAPSPRPLGPQATPVSIRGPPPASQPTPSPHLVPSPAPSPGPGPVP-----------------------SRPPTAEPPPCLRRGAAAADLLSSSPESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQD-----PYEHPERLQQLQQELEAFRGQLGDAGALDAIWRELQEAQEHDARGRSIAIARCYSLKNRHQDVMPYDSNRVVLRSGKDDYINASCVEGLSPY---CPPLVATQAPLP---GTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTERGQPMVHGALSVALSSIRTTETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPGNLLRFIQEVHAHYLHQRPLHTPIVVHCSSGVGRTGAFALLYAAVQEVEAGNG--------IPELPQLVRRMRQQRKHMLQEKLHLKFCHEALVRHVEQVLQRHGVPPPGKP----------------------------------------------VASVNISQKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPLGGLDSPAASLPGLVEPPGLPPASLPESTPVPSSSPPPLSSPLPEAPQPEEEPSVPEAPSLGPPSSSLELLASLTPEAFSLDSSLRGKQRMSKQNFLQAHNGQGLR--------------AAQPTDDPLSLLDPLWTLNKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88902-1", "uniprot_id": "PTN23_RAT", "id": "O88902-1", "name": "Tyrosine-protein phosphatase non-receptor type 23", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LNVNLMLGQAQECLLEKSMLDNRKS---FLVARISAQVVDYYKEACRALEN-----PDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVAYFQSALDKLNEAIKLAKGQPD--TVQDALRFAMDVIGGKYNSAKKDNDFIYHEAVPALDTLQPVKGAPLVKP------LPVNPTDPAVTGPDIFAKLVPMAAHEASSLYSEEKAKLLREMLAKIEDKNEVLDQFMDSMQLDPDTVDNLDAYNHIPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELQEQKLQETLGQAGAGPGPSVTKAELGEVRREWAKYTEVHEKASFTNSELHRAMNLHVGNLRLLSGPLDQVRAALPTPALTPEDKAVLQNLKRILAKVQEMRDQRVSLEQQLRELIQKDDITASLVTT---DHSEMKKLFEEQLKKYDQLKVYLEQNLAAQDNVLRALTEANVQYAAVRRVLSELD------QKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERAQSLCRAQEAARQQ-----------LLDRELKKKAPPPRPTAPKPLLSRREEGEAAEAGDQPEELRSLPPDMMAGPRLPDPFLG-TAAPLHFSPGPFPGSTGPATHYLSGPLPPGTYSGPTQLMQPRA----AVPMAP--------------------GPVLYPAPVYTSELGLVPRSSPQHGIVSSPYAGVGPPQPIVGLPSAPPPQFSGPELAMDVRPATTTVDSVQAPISSHMALRPGPAPAPPQPCFPVPQPVPQSVPQPQ--------------PLPTPYTYS--------IGTKQHLTGPLPQHHFPPGIPTSFPAPRIGPQPPPQLQPQPQPQPQPQPPPQPQPQPQP--QPQPQPQPQPQRPVFGPQPTQQPLPFQHPHLFPSQAPGILTPPP--PYPFTPQPGVLGQPPPTRHTQLYPGPPPDTLPPHSGALPFPSPGPPHP-HPTLAYGPAPSPRPLGPQATPVSIRGPPPANQPAPSPHLVPSPAPSPGPGPVP-----------------------SRPPTAEPPPCLRRGAAAADLLSSSPESQHGGTQPPGGGQPLLQPTKVDAAERPTAQALRLIEQD-----PYEHPERLQKLQQELESFRGQLGDAGALDAVWRELQEAQEHDARGRSIAIARCYSLKNRHQDVMPYDSNRVVLRSGKDDYINASCVEGLSPY---CPPLVATQRPLP---GTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPIERGQPMVHGALSVALSSVRTTDTHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPGNLLRFIQEVHAHYLHQRPLHTPIVVHCSSGVGRTGAFALLYAAVQEVEAGSR--------IPELPQLVRRMRQQRKHMLQEKLHLKFCHEALVRHVEQVLQRHGVPPPGKP----------------------------------------------VASMSVSQKSHLPQDSQDLVLGGDVPISSIQATIAKLSIRPLGGLDSPAASLPSLVEPPGLPPASLPEPTPAPPSSPPPPSSPLPEPPQPEEEPSVPEAPSLGPPSSSLELLASLTPEAFSLDSSLRGKQRMSKQNFLQAHNGQGLR--------------AAQPTDDPLSLLDPLWTLNKT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H3S7-1", "uniprot_id": "PTN23_HUMAN", "id": "Q9H3S7-1", "name": "Tyrosine-protein phosphatase non-receptor type 23", "aln": "MEAVPRMPMIWLDLKEAGDFHFQPAVKKFVLKNYGEN---PEAYNEELKKLELLRQNAVRVPRDFEGCSVLRKYLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKSV----AHEDIKYEQACILYNLGALHSMLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVD--MSRQILTLNVNLMLGQAQECLLEKSMLDNRKS---FLVARISAQVVDYYKEACRALEN-----PDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVAYFQSALDKLNEAIKLAKGQPD--TVQDALRFTMDVIGGKYNSAKKDNDFIYHEAVPALDTLQPVKGAPLVKP------LPVNPTDPAVTGPDIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAYSHIPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQEAVGQAGAIS--ITSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVGNLRLLSGPLDQVRAALPTPALSPEDKAVLQNLKRILAKVQEMRDQRVSLEQQLRELIQKDDITASLVTT---DHSEMKKLFEEQLKKYDQLKVYLEQNLAAQDRVLCALTEANVQYAAVRRVLSDLD------QKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAREAARQQ-----------LLDRELKKK-PPPRPTAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAGPRLPDTFLG-SATPLHFPPSPFPSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAP--------------------GPALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQ----------------------PLPTPYTYP--------AGAKQPIP---AQHHFSSGIPAGFPAPRIGPQ--------PQPHPQPHPS-----------------------QAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQS--PYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVP-----------------------PRPPAAEPPPCLRRGAAAADLLSSSPESQHGGTQSPGGGQPLLQPTKVDAAEGRRPQALRLIERD-----PYEHPERLRQLQQELEAFRGQLGDVGALDTVWRELQDAQEHDARGRSIAIARCYSLKNRHQDVMPYDSNRVVLRSGKDDYINASCVEGLSPY---CPPLVATQAPLP---GTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTERGQPMVHGALSLALSSVRSTETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAHYLHQRPLHTPIIVHCSSGVGRTGAFALLYAAVQEVEAGNG--------IPELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRHVEQVLQRHGVPPPCKP----------------------------------------------LASASISQKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSGPPSSSLELLASLTPEAFSLDSSLRGKQRMSKHNFLQAHNGQGLR--------------ATRPSDDPLSLLDPLWTLNKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VUH6-1", "uniprot_id": "Q9VUH6_DROME", "id": "Q9VUH6-1", "name": "", "aln": "MEAVPRLHMLWFALKSSPEGTSFAALKKYIAEFYHED---PEAYSKEVHALETLRNQAMHTTK--DGAPVMKRYYCQLHALQNRFPQLADR-GIFTFKWKDLYHSAVH----EVTDLRFERAAVLFNIAALHTQSGASVTRGDVDGMKMACTHFQAAAWAYGELRERYANVNGGGDFMTPELLVFQQQVCFAQAQECILEKSLIDNRKP---HIVAKVTAQIVVYYGAALAALLTGGDDGPVAQVIDSSVYKLWKKYVRFKINYLTCILYLYQGQHSEEKRQMGERVTLYQASWDKLEEARKESKGLPDQREINESLSFTADVVEAKRKNAKNENEFIYHEAVPELSTIAAVQGANLVNG------IGFQVSDEEHAGPDIFARLVPMKAHEASSLYSEEKAKLLRKYGALLEEKDTQLESYMSSLTLDNLNINEEQAN-KLPQGIVDRCAALNANKTAISDLVEAMSQLAEITADVETNLGEISSMLEAEAKAEREFQSATGVQ------RTPNAHITELSREFQKYSEAHARAGESNNTLRKAMSLHVNNLKILARPLPEIQQLMPKLSSELNTTEIFRDVKLILNKVNEMKAQRAQFHADLRIAINEDDITGKVIAHG--GQEGLQALFATELGKHDKITELLDQNMVAQGNILQALTENYAKAAPVLKTLQDVK------QKREHFYSSLAASYDVYEDLLAKSAKGLEFYKKLAGNVQKLLTRFRSARDVQSEERQQRMQSVKAATTPVVSKPIAETTPVPAVSSTPKLRDYLKAKAAMADASNPAYVPTVRPVPVGSENPTQAACSYATAPPNEPPPPYSLTQQQYFDPSAAGYTNPMYQQQQQHIAPPAYKAQASPNSQTLHGALGQMNLQGQSQDNNQAGMAYNYGYPSGSVPPLAYAPPGTVPASSASQGLNIQQPLYVATSGNPVSVSNPSELPSTLQAPFVVNPMSNPYQTAAGYSGQAYQQVNAQAQQVTYPTAPSGSSTGQSAQQPLGYAPSQGPQQQAGGYPQSQTPQQQVGAYQQQPLSGYAQQLTPQQQTGYSQSQAPQLQAPSYAQNQQSTGQAQQQQTGYPQTPQQHLAGYAQSQQQATGYPQSQTSQQQTTGYSQSQTPQQPLAYQQQPS--GYPQQQQQQSLAPQQPSLYPSQAVQASPQPIPGQQATPPNAGQPLPYPQQYTDPNAAPAPAPGVSSVPSPVPVPTPAPTSSQAQVPTSPHPSATYTSYSNHPGYSFNPQTGKYEYSSGYQQDTSSLKGSQASQSYQFSQSGKQQSVGTTDSEIASRSNTATGFDSPIVSHTKVNMAAKDSTSAIEGNESSNYYSTPYGYLGSVNPQQQPTPAPPSNSTASIYMQSGASSTAETQTTSSGVPYASSAALTKVEPKPEALPPKVTSNVDLLSDLDIDCSVAVPPPMLPQPVLQPQVVATPTPPASQVSVPVKVESVAEHAAPATAEIPVAATEGTAQTPVTIPSGPKCASLDNLSNCSDLSSLENFDWDSVSVTHSVSEKQTKASATANGHSSSFAFQSETFTDEKTTKYFQKEVESYEKLLENLHVKMLNGKTQLG--AKWQELQQKLDKEAAANKRSTTIAKLFPEKNRSLDCLPYDHARVKLDKQTDDYINAAYMKNLSAGCPNFIVAQTPQPNTINDFWSMIWSEKSRTVVCLHTPNELFDPYWPQALDQPTHYDDYTVTCLKVQQLSHCSEYQLKLSMHGADAVLDLSLLQLKQWTKGAPAQLLGVAENALETHRQRCKAANAPQSPLIMNCLTGSERSELVAIGVCAIIATQNKQPILLNTIDVWSRICAQRQNSLRDSAILEQSMQIVLCNAHNVLNKRGIMTSYQMKMAPQVTAKEQQENKDPLNELDALWKLK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48582-1", "uniprot_id": "BRO1_YEAST", "id": "P48582-1", "name": "Vacuolar-sorting protein BRO1", "aln": "----MKPYLFDLKLKDTEKLDWKKGLSSYLKKSYGSSQWRTFYDEKATSELDHLRNNANGELAPSSLSEQNLKYYSFLEHLYFRLGSKGSRLKMDFTWYDAEYSSAQKGLKYTQHTLAFEKSCTLFNIAVIFTQIARENIN---EDYKNSIANLTKAFSCFEYLSENFLNSPSVD--LQSENTRFLANICHAEAQELFVLKLLNDQISSKQYTLISKLSRATCNLFQKCHDFMKE------IDDDVAIYGEPKWKTTVTCKLHFYKSLSAYYHGLHLEEENRVGEAIAFLDFSMQQLISSLPFKTWLVEFIDFDG----FKETLEKKQKELIKDNDFIYHESVPAVVQVDSIKALDAIKSPTWEKILEPYMQDVANKCDSLYRGIIPLDVYEKESIYSEEKATLLRKQVEETETANLEYSSFIEFTNLP-RLLSDLEKQFSDGNIFSNTDTQGQLMRDQIQTWCKFIQTN--EFRDIEEQMNKIVFKRKQILEILSALPNDQKEN-----VTKLKSSLVAASNSDEKLFACVKPHIVEINLLNDNGKIWKKFDEFNRNTPPQPSLLDIDDTKNDKILELLKQVKGHAEDLRTLKEERSRNLSELRDEINNDDITKLLIINKGKSDVELKDLFEVELEKFEPLSTRIEATIYKQSSMIDDIKAKLDEIFHLSNFKDKSSGEEKFLEDRKNFFDKLQEAVKSFSIFASDLPKGIEFYDSLFNMSRDLAERVRVAKQTEDSTANS----------------------------PAPPLPPLDSKASVVGGP----------------------------------------------------------------------------------------------------------------PLLPQKSAAFQSLSRQGLNLGDQFQNLKISAG--------------------SDLPQGPGIPPRTYEASPYAATPTMAAPPVPPK---------------------------------------------------------------------------------------------------------------------QSQEDMYDLRRRKAVENEERELQENPT----SFYNRPSVFDENMYSKYSS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: .:*** :: * : *: .. :::::: : . : : **. * *: : .: : * : **:.:.** :: : : ::* .: . : .: :.: * :. ::*:*****:** : : .::. :: : * .:: ::*: .:* .*:******.***: * : ..::. * :.: : : : : . : : :. *:* .: .* : : . :: : .. * . *. .: .: . : : : :::::* .:. :: :* :** *::**** :: .. :: ** :* *.: :. :: .: *. :: :. : : . .. . :. : ..* : . :. : . :* :** .* . * * : ... :. . . : . :. .. * .:. .:. : . * . . . * *. :: : . : : . :.. ", "identical_positions": 69, "similar_positions": 205, "identity": "3.68%" }, { "cls_id": "homologset.agr.SGD:S000006006", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q75N33-1", "uniprot_id": "SC16B_RAT", "id": "Q75N33-1", "name": "Protein transport protein Sec16B", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELWVPQ----TQGRTTGPSRDANRRLQS-GHYRPRPHPQYSGDNYHQWQDTHKNSKPQQDPRDDH-QQPHYVPRSGEWSQPVSGADYLKGSYPSHPYSRSGYEDPYQSYHTPTPRDEYAYGNYYYHGHPQLPQGERVARQ--------------------------GSPYIWHEDHR--------DQRHFSEHHWEKHNSTFEANSDTQFQFTSKNPYNDNPASAFGLEQPGEFFP---ESGAQKQKPSLTSK-----SNLLQQHESGLSSS--SYELSQYMTEAP--EQYEPMVSATWRPIQADDTSATVPKAPMRFYVPHVSVSFGPGGQLICVSPNSPADGQTALVEVHSMEVILNDFEDQEEMRAFPGPLIREDIHKVDIMTFCQKKAAQCLKS--------------ETPGSRD-SALLWQLLVLLCRQNGSMVGSDIAELLMQDCKKLEKYKRQPPVANLINLTDEDWPVLSSGTR-----NLLTGEIPLNVDTPAQ-----------------------IVEKFTNLLYYGRKK--EALEWAMKNHLWGHALFLASKMDPRTYNWVMSGFTT-TLALNDPLQTLFQLMSGRIPQAATCCGDKQWGDWRPHLAVILSNQAGDAELY--QRAIVSMGDTLAGKGLVEASHFCYLMAHVPFGHYTV----------KTDHLALVGSNHSQEFLKFATIEAIQRTEIFEYCQMLGRPKSFIPSFQVYKLLYASR---LADYGLASQALHYCEAIGAAVLSEGGSSHPVLLAELIKLAEKLKLSDP------LVL-----------ESRRGDRVLEPDWLVQLRRKHKELEQTRTGDLRDPDLTPSDIYGARGTT--DTPYRDLYGQQNYSEDSEYSSALWPTSEQTSLTNPTPQQ----PFPLQRDTYSERDGPVHMGTPVPLYSVPAT---------------------------HLTVISGSSSGSGVAVTGAPG----------------GRVGEEMLQKHPALGENTVPQEAVQDPDGLAVISS-------------------PQTPLAPRDRSFSEDSAISAKEDEEGTSDGADKPPHPDASQKEKLRDGK-NTKSSGFGWFSWFRS--------KPASSVSTSGDEDSVDSSDSEESPRASPPHHASLGLSPTPPL-------------------------SSPSLPGASTFPRGTGGNSLQ----------GSSNSSGMAEGVGIGGFSGPQGVSSEFYSQPGALPPPP----------------------------------------------------------------------------------------------------------------------TLQGAVPLYNPSQVPQLPTASSLNRPNRLAQRRYPSQPC-------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XT4-1", "uniprot_id": "SC16B_MOUSE", "id": "Q91XT4-1", "name": "Protein transport protein Sec16B", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPWVPQ----TQGRTTGPSRDTNRGLQS-GHYRPRLHSQYSGDKYHQWQDAHKNSKSQQDLRDDH-QQSHSVSRSGEWSQPVSGADYLKGSYPSHLYSRSGYGDPYQRYHTPTPRDEYAYGNYYYHGHPQLLPEERVARQ--------------------------GSPYIWHEDHG--------DQRYFGEHHREKHNGTFGANSDTQFQFTSKNPYRDSPASVSGQEQPGEFFP---ESEAQKQKPLLTSK-----SSLLQQHESGLSSS--SYELSQYMTAAP--EEYEPMVSAAWRPIQADDTSATVPKAPMRFYVPHVSVSFGPGGQLVCVPPNSPADGQTALVEVHSMEVLLNDFEDQEEMRAFPGPLIREDIHKVDIMTFCQQKATQCLKS--------------ETPGSRD-SALLWQLLVLLCRQNGSMVGSDIAELLMQDCKKLEKYKRQPPVANLINLTDEDWPVLSSGTR-----DLLTGEIPPNVDTPAQ-----------------------IVEKFTKLLYYGRKK--EALEWAMKNHLWGHALFLASKMDPRTYNWVMSGFTS-TLALNDPLQTLFQLMSGRIPQAATVCGDKQWGDWRPHLAVILSNQAGDTELY--QRAIVSMGDTLAGKGLVEASHFCYLMAHVPFGHYTV----------KTDHLALVGSSHSQEFMKFATIEAIQRTEIFEYCQMLGRPKSFIPSFQVYKLLYASR---LADYGLASQALHYCEAIGAAVLSQEGSSHPVLLAELIKLAEKLKLSDP------LVL-----------ERRRGDRDLEPDWLVQLRRKHKDLEQNRTGAPRDPDSTPSDIYGAGGTT--DTPYPDLSGHQNYSEDSEYSSTLWSTAEQTSLTNPLAQQ----SFPLQRDTYSG-----HMGTPVPLYSVPAT---------------------------HLAVTSG-ASGSSVAVTGTPG----------------GRVGEDMLRTHPAFGENTMTQEPLEDPDGLEVISS-------------------LQTPAAPRVPSFSEDSAASAKEDEEGSSDGADKPSHPDASQKGKLGDGK-NTKSSGFGWFSWFRS--------KPASSVSTSGDEDSSDSSDSEESPRASSPHHASPGLSPTPPL-------------------------TSPSLPGASTFSRGTGGSILQ----------GSSNSSGIAEGMGIGGFSGTQGVSSEFYSQPGALPPPP----------------------------------------------------------------------------------------------------------------------TLQGAVPLYNPSQVPQLPTASSLNRPNRLAQRRYPTQPC-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96JE7-1", "uniprot_id": "SC16B_HUMAN", "id": "Q96JE7-1", "name": "Protein transport protein Sec16B", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELWAPQRLPQTRGKATAPSKDPDRGFRRDGHHRPVPHSWHNGERFHQWQDNRGSPQPQQEPRADHQQQPHYASRPGDWHQPVSGVDYYEGGYRNQLYSRPGYENSYQSYQSPTMREEYAYGSYYYHGHPQWLQEERVPRQ--------------------------RSPYIWHEDYR--------EQKYLDEHHYENQHSPFGTNSETHFQSNSRNPCKDSPASNSGQEWPGELFPGSLLAEAQKNKPSLASE-----SNLLQQRESGLSSS--SYELSQYIRDAP--ERDDPPASAAWSPVQADVSSAG-PKAPMKFYIPHVPVSFGPGGQLVHVGPSSPTDGQAALVELHSMEVILNDSEEQEEMRSFSGPLIREDVHKVDIMTFCQQKAAQSCKS--------------ETLGSRD-SALLWQLLVLLCRQNGSMVGSDIAELLMQDCKKLEKYKRQPPVANLINLTDEDWPVLSSGTP-----NLLTGEIPPSVETPAQ-----------------------IVEKFTRLLYYGRKK--EALEWAMKNHLWGHALFLSSKMDPQTYSWVMSGFTS-TLALNDPLQTLFQLMSGRIPQAATCCGEKQWGDWRPHLAVILSNQAGDPELY--QRAIVAIGDTLAGKGLVEAAHFCYLMAHVPFGHYTV----------KTDHLVLLGSSHSQEFLKFATTEAIQRTEIFEYCQMLGRPKSFIPSFQVYKLLYASR---LADYGLVSQALHYCEAIGAAVLSQGESSHPVLLVELIKLAEKLKLSDP------LVL-----------ERRSGDRDLEPDWLAQLRR---QLEQKVAGDIGDPHPTRSDISGAGGTTTENTFYQDFSGCQGYSEAPGYRSALWLTPEQTCLLQPSPQQ----PFPLQPGSYPAGGGAGQTGTPRPFYSVPET---------------------------HLP-----GTGSSVAVTEATG----------------GTVWEEMLQTHLGPGENTVSQETSQPPDGQEVISK-------------------PQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRS--------KPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSP-------------------------ESPPLPDVSAFSRGRGGGEGR----------GSASSGGAAAGAGVGGLSGPESVSFELCSNPGVLLPPP----------------------------------------------------------------------------------------------------------------------ALKGAVPLYNPSQVPQLPTATSLNRPNRLAQRRYPTQPC-------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QAT4-1", "uniprot_id": "SC16A_MOUSE", "id": "E9QAT4-1", "name": "Protein transport protein Sec16A", "aln": "MQPPPQAVPSGVAGPPPAGNPRSMFWANSPYRKPANN-APVAPITRPLQPVTDPFAFNRQTLQNTPVGSSSKSSLPNLPGPALSVFSQWPGLPVTPTNAGDSSTGLHEPLSGTLSQPRADASLFPPASTPSSLPGLEVSRNAEADPSSGHEVQMLPHSAHYIPGVGPEQPLGGQMNDSGSGPDQPMNRHAPHDGAVTHAASPFLPQP--QMPGQWGPAQGGPQPSYQ-HHSPYLEGPVQNMGLQAASLPHFPPPSSLHQGPGHESHAPQTFTPASLASGEGNEIVHQQSKNHPLSSFPPKHTFEQNSRIGNMWASPELKQNPGVNKEHLLDPAHVNPFTQGNSPENQAHHPPVAATN-----HALQEAASGALSMFFQGEETENEENLSSEKAGLDKRLNLDSFSSTSRLGHPPPPGASGVYQAFPRGPSSEAAQEGDAQPYFSQSVGVRLDKQSTVPPANDAWGDVPGTGTRCASGPQCENVENLEFVQNQEVLPRETLSVDPFPLSDQIRYGPLPGPAASRPATVGLTRGGGLNLEAPDTPLHPTRPDSVSSSYSSHSHRSPPGS------ARPQELVGTFIQQEVGKLEDD-----TSGSFFKQIDSSPVGGETDEVTGSQNCCSSLSQPSTPSPPKPTGVFQTSANSSFEPVKSHLVGVKPVEADRANMVVEVRGTQYCPKKRRAAVAPPDATSGNLEQPPDNMETPCAPQACPLPLSTTGEAGQLVSNTAGTPLDTVRPVPDKRPSARAQGPVK-CESPATTLWAQNELPDFGGNVLLAPAAPALYVPVKP-KPSEVVHHPEKGMSGQKAWKQGSVPPLQNQDPPGASENLENPPKVGEEEALPVQASSGYASLLSSPPTESLHNQPVLIAQPDQSYNLAQPINFSVSLLNPNEKNQSWGDAVVGERSIVSNNWALGGDPEERAALSGVPASAVTGASLPSSIPQNCAPQGSGSSEMIASQSASWLVQQLSPQTPQSPHPNAEKGPSE------FVSSPAGNTSVMLVPPASSTLVPNSNKAKHSSNQEEAVGALDFTLNRTLENPVRMYSPSPSDGPASQQPLPNHPRQSGPGLHNQDHFYQQVTKDAQ--DQHRLERAQPELVPPRPQNSPQ-VPQASCPEPSNPESPPTQGQSESLAQP--PASPASVNTGQLL-PQPPQASSASVTSTNSSQAAVRSEQLWLHPPPPNTFGPAPQDLASYYYYRPLYDAYQSQYPSPYPSDPGTASLY-YQDMYGLYEPRYRPYDSSASAYAENHRYSEPERPSSRASHYSDQLAPRQGYPEGYYNSKSGWSSHSDYYANYYSGQYD-YGDPSRWDRY-YGSRLRDPRTWDRRYWYDSEHDPYRKDHYAYSDRPEKC-----DDHWRYDPRFTGSFDDDAEIHRDPYGEEADRRSIHSEHSARSLRSTHSLPSRRSSLSSHSHQSQIYRSH-HVTGGSFEAPHAPGSFHG--DYAYGTYASNFSGAHGFPEYSYPADTSWPAVEQVPSRPTSPEKFTVPHVCARFGPGGQLLKVIPNLPSEGQPALVEIHSLETLLQHTPEQEEMRSFPGPLGKDDTHKVDVINFAQNKATKCLQN--------------ESLIDKESASLLWKFIILLCRQNGTVVGTDIAELLLRDHRTVWLPGKSPNEANLIDFTNEAVEQVEEEESGEAQLSFLTDSQTVTTSVLEK-----------------------ETERFRELLLYGRKK--DALESAMKNGLWGHALLLASKMDSRTHARVMTRFAN-SLPINDPLQTVYQLMSGRMPAASTCCGDEKWGDWRPHLAMVLSNLNNNMDVE--SRTMATMGDTLASKGLLDAAHFCYLMAQVGFGVYTK----------KTTKLVLIGSNHSLPFLKFATNEAIQRTEAYEYAQSLGAHTCSLPNFQVFKFIYLCR---LAEMGLATQAFHYCEVIAKSVLTQPGAYSPVLISQLTQMASQLRLFDP------QLK-----------EKPEEESFVEPAWLVQLQHVERQIQEGTVLWSQDGTEPQQCRITSGSEVEQSDGPGLNQQAGPQADNPLLMPSTEPLMHG---VQLLPTA----PQTLPDGQPAHLSRVPMFPVPMSRGPLELSPAYGPPGSALGFPESSRSDPAVLHPGQALPPTTLSLQESGLPPQEAK------------------SPDPEMVPRGSPVRHSPPELSQEEFGESFADPGS-------------------SRTAQDLETSPVWDLGSSSLTRAP-SLTSDSEGKKPAQAVKKEPKEPKKTES--WFSRWLPGKKRTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSFPRVPQVAP---------------------TGPAGPP-TASVNVFSRKAGGSRARYVDVLNPS--GTQRSEPALAPADFFAPLAPLPIPSNLFVPNPDAEEPQPADGTGCRGQAPAGTQSKAESTLEPKVGSSTVSAPGPELLPSKP-------------------------------------DGSQGG--------------------EAPGDHCPTGAPHGGSVPFYNPAQLVQASVTSGNSRPGRIGQRKYAALN--------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZTA3-1", "uniprot_id": "A0A8I5ZTA3_RAT", "id": "A0A8I5ZTA3-1", "name": "Protein transport protein sec16", "aln": "MQPPPQAVPSGVAGPPPAGNPRSSFWANSPYRKPANNNAPVAPITRPLQPVTDPFAFNRQTLQNTPVGSSSKSSPPNLPGPALPVFSQWPGLPVPPTNAGDSSTGLHEPLPGTLSQPRADPSLFPPASTPSSLPGLEVNRSAEVDSSSGPEVQMLPHPPHYIPGVGPEQPHGGHLNDSGAGPDQSMNRHAPHDGAVAHAASPFFPQP--QMPGQWGPVHGGPPPSYH-HHSPCLEGPVQDMGPQAASLPHFPSPSSLHEGPGHESRVPQTFTPASLASGEGNEIVHQQSKNYPSSSFPPKHSFEQNSRVGNMWASAEFRQNPGVNKEHLLDPAHVNPFTQGNSPENQVHHPPVAATN-----HALQEAASGALSMFFQGEETENEENLSSEKAGLDDRLDSGSFSSTSRLGHPPLPGAGGVYQ---------AAQEGDVQPYFSQFVGIRHDKQTTMTPANDAWGDIPGAGTHCASGPQCENVENLEFVQNQEVLPRETVNVDPFSPSDQFRYGPLPGPAASRPVTSGLTRGGGLNLEAPDMPLHPTRPDSVSSSYSNHSHRSPPGS------ARPQELVGTFIQQEVGKLEDD-----TSGSFFKQIDSSPVGGETDEMTRSQNYCSSLSQPSTPSPPKPTGVFQTSANSSFEPVKSHLVGVKPVEADRANMVVEVRGTQNCQKHG-AAVLPPDATPGNLEQPPDNMETLCAPQACPLPLSTTGEAGQLVSHTAGPPLDTVRPMPDKRSSARAQGPVK-CESPATTLWAQNELPDFGGNVLLAPAAPALYVPVKP-KPSEVVHHPEKGMSGQQSWKSGSVPPLQNQDPPGASENLENPPKVGEEEALPLQASSGYASLLSSPPTESLHNQPVLIAQPDQSYNLAQPINFSVSLPNPNEKNQCWGDAVVGEKSMVS-TRALGADHEEHAALSAIPASTVTGSSLPNSVTQNCAPRGSGSSEMIASQPASWLVQQLSPQIPQSQHPNAEKGPSE------FVNSPA-NGSVMLAPPANSAVIPNSNKGYHSRNPEEAIGALDFTLSRTLENPVRMCSPSHSNSPASQQPLANHPRQSGPGLHNQDHFYQQVTKDAQ--DHRSLERGQSELVPPPPQNSPQQVPQAACPEPSNPESPPTQGQSEGLVQP--SASPAPVNTGQQ--PQPPQSSSASVTSTNSNQAAVRSEQPWLHPPP-TTFGPAPQDLASYYYYRPPYEAYQSPYPSPYPSDPGAASLY-YQDIYGLYEPRYRPYDSSASAYAENHRYSEPERPSSRASHYSDQLTPRQGYPEGYYNSKSGWSSHSDYYANYYSGQYD-YGDPGRWDRY-YGSRFRDPRTWDRRYWYDSDHDPYRKDNYAYSDRPEKC-----DDHWRYDPRFTGSFDDDTELHRDPYGEEVDRRSIHSEHSARSLRSTHSLPSRRSSLSSHSHQSQIYRSH-HVTGGSFEAPHAPGSFHG--DYAYGTYASNFSGAHGFPEYSYPADTSWPAAEQVPSRPTSPEKFTVPHVCARFGPGGQLLKVIPNLPSEGQPALVEIHSLETLLQHTPEQEEMRSFPGPLGKDDTHKVDVINFAQNKATKCLQN--------------ESLIDKESASLLWNFIILLCRQNGTVVGTDIAELLLRDHRTVWLPGKSPNEANLIDFTNEAVEQVEEEESGEAQLSFLTDSQTVTSSVLEK-----------------------ETERFRELLLYGRKK--DALESAMKNGLWGHALLLASKMDSRTHARVMTRFAN-SLPINDPLQTVYQLMSGRMPAASTCCGDEKWGDWRPHLAMVLSNLNNNMDVE--SRTMATMGDTLASKGLLDAAHFCYLMAQVGFGVYTK----------KTTKLVLIGSNHSLPFLKFATNEAIQRTEAYEYAQSLGAHTCSLPNFQVFKFIYLCR---LAEMGLATQAFHYCEVIAKSVLTQPTAYSPVLISQLIQMASQLRLFDP------QLK-----------EKPEEESFVEPAWLVQLQHVERQIQEGTVLWNQDGTEPQQCHITSGSEVEQPDGPGLNQQAGPRADNPLLMPSTEPLVHS---VQLLPTA----PQTLPDGQPAHLARVPMFPVPMSRPPLELSAAYGPPGSVLGFPESSRSDPAVLHPGQALPPATPGLQESGPPLQEAR------------------SPDPEMVPQGSPVRHSPPEPREEEFGKNVADLGS-------------------SRTAQDSETSPVWDLGSSSLTRAP-SLTPDSEGKKPAQAVKKEPKEPKKTES--WFSRWLPGKKRTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSFPRVPQAAP---------------------TGPAGPP-MASVNVFSRKAGGSRARYVDVLNPS--GTQRSEPALAPADFFAPLAPLPIPSNLFVPNPDAEESQPADGTGCRGQAPAGTQSKAEPTLEAKVVSSTVSAPGPELSPSKPA------------------------------------DGSQGGELSRCSSLSSLSQEVSRHFHQAPGDHCPAGATPGGSVPFYNPAQLVQASVTSGTSRPGRIGQRKYAALN--------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15027-1", "uniprot_id": "SC16A_HUMAN", "id": "O15027-1", "name": "Protein transport protein Sec16A", "aln": "MQPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQ-HRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPENRTHHPLGAGAGSGCAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAP-----------------THVGAGSLCQALLPGPSNE------AAGDVWGDTASTGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTG-------APDATLHTVHPDSVSSSYSSRSHGRLSGS------ARPQELVGTFIQQEVGKPEDE-----ASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCRPAAALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVK-CESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKP-QPP-VVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEALQSQASSGYASLLSSPPTESLQNPPVLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGDRPAVS-SWALGGDSGENTSLSGIPTSSVLSLSLPSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQ--GQPGLERAQQELVPPQQQASPPQLPKAMFSELSNPESLPAQGQAQNSAQS--PASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLY-YQDVYSLYEPRYRPYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQGYPEGYYSSKSGWSSQSDYYASYYSSQYD-YGDPGHWDRYHYSARVRDPRTYDRRYWCDAEYDAYRREHSAFGDRPEKR-----DNNWRYDPRFTGSFDDDPDPHRDPYGEEVDRRSVHSEHSARSLHSAHSLASRRSSLSSHSHQSQIYRSH-NVAAGSYEAPLPPGSFHG--DFAYGTYRSNFSSGPGFPEYGYPADTVWPAMEQVSSRPTSPEKFSVPHVCARFGPGGQLIKVIPNLPSEGQPALVEVHSMEALLQHTSEQEEMRAFPGPLAKDDTHKVDVINFAQNKAMKCLQN--------------ENLIDKESASLLWNFIVLLCRQNGTVVGTDIAELLLRDHRTVWLPGKSPNEANLIDFTNEAVEQVEEEESGEAQLSFLTGGPAAAASSLER-----------------------ETERFRELLLYGRKK--DALESAMKNGLWGHALLLASKMDSRTHARVMTRFAN-SLPINDPLQTVYQLMSGRMPAASTCCGDEKWGDWRPHLAMVLSNLNNNMDVE--SRTMATMGDTLASRGLLDAAHFCYLMAQAGFGVYTK----------KTTKLVLIGSNHSLPFLKFATNEAIQRTEAYEYAQSLGAETCPLPSFQVFKFIYSCR---LAEMGLATQAFHYCEAIAKSILTQPHLYSPVLISQLVQMASQLRLFDP------QLK-----------EKPEEESLAAPTWLVHLQQVERQIKEGAGVWHQDGALPQQCPGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSA----PQTLPDGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPS---------GPGLPPGVPPLQERRHLLQEAR------------------SPDPGIVPQEAPVGNSLSELSEENFDGKFANLTP-------------------SRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGES--WFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAP---------------------PALPGPP-GAPVNMYSRRAAGTRARYVDVLNPS--GTQRSEPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEPKVLSSAASLPGSELPSSRP-------------------------------------EGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPPSGAMPFYNPAQLAQACATSGSSRLGRIGQRKHLVLN--------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B225-1", "uniprot_id": "A0A8M3B225_DANRE", "id": "A0A8M3B225-1", "name": "Protein transport protein sec16", "aln": "MQPPPRTTPPGASGPPPPSGGPNSFRRNRPHKHGAAS--AMTPAAPSTMPVTDPFAFGRQNFSSMAGSSQ---APPTNSNPLPMQSPPLPGFNPTAPPQGPP------PGPAQAASPGPPPRIFTPQPVPSRPGSSSIPPPAEAGYFSSQ--EPIPYIAQLPNPAPPLIPSTSHPPSTTPTPP-------------VQSQAPFHSQPTPPLPSHWVPEHGSRPPSVQNYFQPTSDLPSQPFQAQAP----HPGPSPLTAPPPVPSPLTAPPPLTSPLTAPPLTQSQNQFQSAQPNVSGPAATYQQNS----HFPAHNYFSQSGGPSEPWFN-------QNPQDPSQRAYHVPYSEVP----------SDSGTLSMFFGGNDVENEETLTGE--GRVNGIHQPLHSTTEFSG-----------------------------------------------------PYLNDSGNIRAGTGPSDSVENLECVPNQEVLPSEPP------PSHAFEGGPN--------------------LETPDSAPRLARSASVSSSYSNVSHSSGHGAHSGGHVPRRQQVVGTFIQQESPRPPDHPPLHPSTGGYFEQIDSNPAAEASPTFP-------------TPSPPKPVGVFQASANSSFEPVRSHGVGVRPAEVDRARVVMEKGG--------------RDMQPGNLEHPPDNLETIYLS--------------------------------ERRPSSRAQGARRPIESPATALWAQNDTASLSANILLAPAAPSLTATFVPAHPSEVIQPPEDGPLDLHPARPDPQPP---------SENLEIPPDS------TPQASLGYASLLVTSPPEEALNQPVLIAPPSSNYSLIS----SQNLLQPS---------------------ILPSPQETAAPVHPHPQSSLTNQMPQNSPPTNQPPLLFSQTPVNFSSSSAQGVLNLTREANDGQAARPN-----------LSRAQSLKGDSQFLPPS-ATQAPPSSAASTNHNQPSNYQLLDFSMHQ----------PQSTNQVTSVPAVSQSTHPAG-LVNNTPGFYLQVTKDAQQGGQSDTDSLSHQQNSNPPLPSSNQLDNNQTLN-SHPPPPPAQNQPPPQAPPTHPGAPPTGPGSAQPPPYPPQSGNSTTQPPQEPQRPPSSLGSQSGYGVPPAMPPGPGYPGYYPGAYPEYQDGRVPYPPQYPVDPRTQNYY-QDDPYRRGDPRYGWYDGQNPGYREAER--QPERPSSRTSQYSDRPSSRQGYQEDFS--RSSRSAYDEYYANYYKRQYDAYGDRSRWYDPNAAYDPRYKAYYDQMYGWYYNQDGYRGGQAYYNQQYQNRGREGYDDPWRYYPGYDSSFDDDSR-RRDPYADDFDRRSVHSEQSAHSVHSSH---SRRSSFSSRSQQSQVYRSQPDLVSAAYDATG--TTLPA--DYTYSQYPNPSDTVNYGQDPYNSADNTWSAPEQPPPRPLTPEKFSIPHRCARFGPAGQLILVQPNLPSAGQPTLVEIHSMETLLQDSPEQSDMRSFPGPLVKEETHKVDVMKFAQNKAQECLRN--------------DDLIDKDSAYLIWEFIVLLCRQNGTVVGTDIADLLLKEHRSVWLPGKSPNEANLIDFNNEAIEHAEEDMG---QMSLLSDTFMGVPENIGK-----------------------DTERFRELLLFGRKK--DALESAMKNGLWGHALLLASKMDNRTHARVMTRFAN-SLPINDPLQTVYQLMSGRMPAAATCCGDEKWGDWRPHLAMVLSNLTHTLDLD--TRTISTMGDTLASKGLVDAAHFCYLMAQVGFGVYTK----------KSTKMVLISSNHSLPFLKFCSSEAIQRTESYEYAQSLGSQPLSLPNFQVFKFIYACR---LAESGLCAQAFHYCEVISRTLLSLPEYYSPVFISQLIQMSLRLRFFDP------QLK-----------ERPEQELFIEPDWLLHLRQLDGQIKEGVISLRTDRSTPQLYPCSTPSSEDQCSPPEP-PALTPDPHNALMTSLVPP-----AAVQLMPPA----PPTILQDGAVSLQQVPPPSESVPFYPVAPGPPQPNFVAPYQPEMQEQYMPMPPQIPQHMPPQMPTYNPAEMPPQMPQGMPGQMPPPMHGAERGSAPSSPQQFPQPSPTFANPPPPGKD-FYDEMARLGPGRRSRTTSQSSMHMAPGRRSRTTSESSNHSGRERSSSFANQGSPPPPPIPEAPPQDVPERTKKDSPKKQGSGGGLLTWLFPKRKNEAHLPDDKNKSIVWDEKKQKWVNLDEPEEESKPPPPPPTGFPKAPMSAPAMVP-----------------PGVAGPPSGPPVNMFSRRAG-TRSRYVDVLNPGRGGAKAVASVPPPADLFAPLAPMAMPANLFTPAAAPDEQQPMEGS--VPDTSGENTLQTSATVPQMFNPNAALPPGPE--------------------------------------------GTQSGELSRSSSMSSLSREVSQHLNQAPAQQPVQGAPPAGGVTFYNPSQFAQSVPTN-RTRPGRLGQRGYPTPK--------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9P971-1", "uniprot_id": "A0A8M9P971_DANRE", "id": "A0A8M9P971-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMEPRREGWRMPGYQYQSSDRDDHYRSSHQSQYYYPP-TESRG-RERQWQQVDPRYGSYMTSPPPKPEYIPGYSSAYASNQPSHFRPHSRQEYDYSTSSYWPYREDYGYYDYHG-YHRTQYS-SPDGGGWSQT---------------------------------------------DGWRTEGHQGQGLTQES--ARASYSDQQGYSFKTDSQHDRGVSERH-----RESMDNGNGTGEVYDNS------ALANSKASGLSSS--SYELSQYMNGAE----------QSELELISHTGVVPVEVAPLKFSIPHVAVSFGPAGQLVWVSPALASEGEPAQVELHSLEVILCDTHAQHDMRDFPGPLAREDLHKVDAINFAIQMSEMCLKD--------------EKLEDHTSAALLWHFLILLCRQNGRILGSDVAELLMRESSSLGVWGDTAEPADGKSLIDLSETPTVEKETLN-FSDLLTGFPPTDKEAEEQ-----------------------NLQKYTKLLLSGRKK--EALESAMQSGQWGHALFLASKMDSRSYNTVLSRFTG-SLTPSDPLQTLFQLLSGRIPAVSMSWSSEKWGDWRPHLAVMLSNETTDPVIH--HRSIIAMGDTLASRDMLFASHICYLTAQCPFGWYRN----------RSERLVLLGSKQSVMFSKFCHNSAIRCTELFEYCQRLGNAEFVIPAFQVYKFLYACR---LLDCGLVSQAFHYCEVVGKALLRIDQPH-VVLLGELIKLVDRLKFSEA------QLN-----------DTGDGQLFLDPDWLVQIRCRHQTLLGENYCSETYQSPAEETSWTQDSNKYSDFTEGQAEAIDNPSTETESSNPPYSAIPH---TDAQFEG----TYSLMSHSYSSEEQAPKTIAPVPLYPTQQP--------------------------MTLPPVTP----------------------------------TEMFGPPSVSVEQSYANDSSTYHDDLHNAMSS------------------SSPRNYTDTGGDFSAEAMIASENDATVGKVNQFGTFPSEDNKTKTQSAKASKPGWFSGWFKSKPK---------------DEPKEEIPDPDSPTEESTANFPFPPPPPRSILKTE-----------------------------QPQFNPFSKRAGQSQNQQQTLSEGP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JEM2-1", "uniprot_id": "X2JEM2_DROME", "id": "X2JEM2-1", "name": "", "aln": "---MLHNNAPWLPPHQQQQQQAPQQHPTPQQQHAMPQQQQTLPAQQQQQQVYASQMFQQHQPNYWPEDQHQQQQQPQSLNYNNYFPGQQQQHPMQQQQLPPQQQLPPQQQQPTQQQHTIQQQLYYPTQQQPQVPAPAEPALDSFDNNNSGGGGGGGRSDGWGDWGDWNDNSNNNNSNGTDGLLEPTGQLLEDSFNVQSSQGSWQAFATSNNVNNNGELPPPANPQSTSLQQQPLNQQSIPLLHQQPQSPPELGQEPELDAIVPPQAFQNQPPTAAPPPTSLTSFSAQMTAVGSPIYAVGASSAHSAGVGASPAPPTGVVAPPAHLAGIGAPPAHLAGVGASPAPSALVGASP----------------------------------------------------------------------------------------------------------------APIIGVGAPPVGAPPVGAPP----------------------------------------------------ADATTIAPPAALPPSIVPSSGSNPFKRSTGLN-----------------------------------KRVNIMADPAAG-------------------APSPPAPAAAIAPVAPVAPIPPPADQLFGMPAEAHGEGFN-----------------------------------------------------------------------------LIAAPPVEASLGTPLSAPIPAPIPVPNASLYASPAVPQAFAHLEPDNQEVLSAPNDERAQYLQTSHLSEQLGEGEADQDAGLLPPPGLSRLVLGQPELDSQQQRQVTGATEQPPLNVAQAAALHMQERRAD-----------------------------------GEDTSDGEQQVRNIQTPPRRVVTGVETNAPSLREQREVVLDGENLEDREAIPPPTLAELPTTSVHHNILPDEAEQLHHNNPPQAMTPLNAQQPHQQQSTLQQQHQQHSTTQQEKKRAAVGRRTTASLDLESDESDEFLQSERERDRERERRDLMEERHSRGRSHSHYPYEGETEDSVRGAAHHETKSLRETHHKRNHDSARSRRHQDPKVERERERDRERDRTWRRRSNKYHSGGEDPDRSYDHSRRYNNSNYEGESDNPEYNHMGDAELDGSGGRSSKTSRHRRSAAEEDFDDYERERNRSRRSTKPQSSAEKSRSSGGRRNYENSGRSARADDGRRRYQDQRNPGAQYPVSATGYVPYGMYEQMSRNPQVYADMYAKFYGQMINSMNAAVSAAASKGGVPAGAGVIPGLMPSAVPVSAAQLVAATSGGSVSGSSEAAMLRERERYTHAYITQANEFHRHQYKELIYQQQQQQQQQQQQQQQREDHLNSSFSVAEDNASFYGSHGGGSIYNQYQSYPLSSARSLSNLNGDGRNSRCGPYYAGSECGLDIRAAADAAPSTYGGVAGTAGPVTNTAVARPPRRRTPLQFSRPHLVASYAMS-LLLKVKPKYAGRGR--LRNDVEVAPPRIRDGTSSLLRMYPGPLQGRKLHKDKIISFCKEQIRLGPTKGCTALYATQKKPQGSVTKYRASHALMWHLLILLLRQNGYIADTDVGDLLLENQQEYPYDPSEFEAENEPDADAEQDAAAPADKTVDSDLDSESAAGVTPAEPLAAGAATSSINGADAANAATPLSEQAATDKFRSYVLRGNVE--EALQWATDNGLWTHAFFLALYEDRYALTDVAQKFLNRAIKANDPLQTLYQMKSCHTPACVSQLRDEQWGDWRSHLSILVTNKSRQPEYD--RSSVVALGDTLFQRGDIYAAHFCYLVAQEEFGRYDSSATELTTLTANVPRLILLGSSHYKHFNEFASNEAIIMTEIYEYARSLFDPKFSIAHFQHYKFLLATR---ILDYGQHFRCTNYLEQIARHIELKPESYDSNFIQRVCGLAERLRYHDP------ILINRVSFASPPNATSKDSAAAEEKAWLRQLRSLAYVQPQQEQLQQLQQNQQVQQEQNDIDQQFAEVNKQFRELNMQYESNSNMENTLQPQLPPVDQQPPQQQQQVL-SESYQQPTQQYYEPPPQAPTESDPYGQGQPSYYDPNAGQLHYDPNAAQHQYDQQQPQPQPTPSYGQIEPGTEAYQPGQATADPAAVPSGYGYDYWSGTQQPPYGDEPNENQAALKDEEEEDEEQDEQQILQYAKQQILQQTKQQQLQQEQHTRSNGAASINNRFKSNALKQERSSGSLRKRQEASRTATIAAAAAAIAQITPATVAAAATPPAASAKAFNLNDVSSFSSTNKRHQATSSSNNRSSSNQAAAAAAATKAAAIATVPAAPNQLLSCRKSNSQNSPYLATPKTLTTPTRFIAAKAATVTATPTAPATSTTTSTTIGARGSSTKRVYFNLPSTIAESEQEFEHELDYDEEMEEENSMALAQAKPNVHLARKPHIVFNGTYPIDMPLTQGQSQLKSNSYDPEANADRGDLQRYRNYMLHDYVIDEDAEGEEQAEEEGEEDEYGDGDEDLFPYADDDESFDDGDYYTHQLLNKYGIIPSGEKQRVERTPASVEAATSAAQPQHVWSMKELIANPAIPLNYKKMCSEVEQSLSRFENYLDSKKEQQVPPGAAVRTFDIDAPTRRGHRSSTSTNAGLDLRSKKKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48415-1", "uniprot_id": "SEC16_YEAST", "id": "P48415-1", "name": "COPII coat assembly protein SEC16", "aln": "-------MTPEAKKRKNQKKKLKQKQKKAAEKAASHSEEPLELPESTINSSFNDDSVNRTESDIASKSDVPPVSSSTNISPANETQLEIPDTQELHHKLLNDSDQHDITADSNDLPDNSIVEHDSVITQTKPAMSQEYEETAAHLSSRNPSLDVVAGELHNNNEHTQKIAVSAVEEDSFNEEEGENHDSIIISSLNDATPSQYNHFLPSDGNLLSPELSSGDTPTHNVPLGTKDNEINDDEYCNDKEISLNANNVLPDELSKEEDERLKLETHVSTEEKKQDIADQETAENLFTSSTEPSENKIRNSGDDTSMLFQDDESDQKVPWEEDVKKDFHNENTNNTQESAPNTDDRDKGYE------------------------------------------------------------------------------------------------------GNEALKKSESCTAADERSYSEETSEDIFHGHDKQVVEG----------------------------------------QNDFTGKNIENESQKLMGEGNHKLPLSAEADIIEPGKDIQDQAEDLFTQSSGDLGEVLPWESTDKNADVTSKSQEKHEDLFAASGNDEKLPWEVSDGEVSSGKTENSMQTSTEKIAEQKFSFLENDDDLLDDDDSFLASSEEEDTVPN-------------------------------------------------------------TDNTTNLTSKPVEEKKASRYKPIIEEEAGMRQEQVHFTNTTGIVTPQQFHGLTKTGLGTPNQQVSVPNIVSPKPPVVKDNRSNFKINEEKKKSDAYDFPLEIISESSKKGHAKPVAVPTQRFGSGNSFSSLDKPIPQSRK-------------------------------GSNNSNRPPVIPLGTQEPRSSRTNSAISQSPVNYAFPNPYKIQQLQQAPIQSGMPLPNTNIPPPALKVETTVSAPP-------IRARGVSNASVGSSASFGARHATQYGLNNGVPPVSPYGQATINLPTANKYAPVSPTVQQKQYPSVVQNLGASAVNTPNFVKTHRGHTSSISSYTPNQNEHASRYAPNYQQSYQVPYTSQPVGPVAGNSSYQSQTRSSYAVPMMPQAQTSASIQPHANIQPPTGILPLAPLRPLDPLQAATNLQPRASNITAANSLPLANLPLAENILPEIITHRATSSVAPPRQENNPIKIDNEALLRRQFPIFHWSAANKVVYAVPPIPDQSQYMISSSIVQEIKVTPIDQIIKPNDMLKSFPGPLGSAKLKKKDLTKWMETTIKSISENESSTDMTIWQLLEMKLNDKVNWKNISKLLYNSDELLMYLSQPFP-------NGDMIPNAYRLDINCQMRVLAFLQTGNHDEALRLALSKRDYAIALLVGSLMGKDRWSEVIQKYLYEGFTAGPNDQKELAHFLLLIFQVFVGNSKMAIKSFYTNNETSQWASENWKSIVAAVLINIPENNEDPLLIPPVVLEFLIEFGIFLTKKGLTAAASTLFIIGNVPLSNEPVMADSDVIFESIGNMNTFESILWDEIYEYIFSYDPKFKG----------FSSILPQKIYHASLLQEQGLNSLGTKYTDYLSSSVRKLPKKDILTINLTRELSEVASRLSESNTGWLAKPKLSSVWGQLDKSFNKYIGGDDIDALN-------------------KKNDKKKVFDGFTPGSSANSSTVDLTQTFTPFQAQVTSQSYVDTTALLHNAHNVPSHSVLHSKPSNVSKGLVEANLPYTHRIGDSLQGSPQRIHNTQFAAAEPQMASLRRVRTDQHTNEKALKSQQILEKKSTAYTPQFGQNHSVPMEKS-------NSNVPSLFADFPAPPKLGTVPSNYVSSPDLVRRESIISTGSEFLPPPKIGVPTKANSSQGSLMYSPSVEALPIDPVVPQVHETGYNDFGNKHSQKSMPEDESHTSHDNSNADQN--------TLKDSADVTDETMDIEGPGFNDVKNLLPMEPNHQPTSTVNPIQTISDDIQPILQTNVEVRGTDASKMENSLPSIENERSSEEQPENISKSASSAYLPSTGGLSLENRPLTQDENSISETVQSTYLPAGSISMEAKPISQVQDVPRNVNNKASKLVEQHMAPPKPKSTDATKMNYSPYVP---------------QSTAASADGDESTILKTSPAIYARTHQAHASNPSQ-----------------YFPLVNQANETASFELSESTSQAQSNGNVASENRFSPIKKAEVVEKDTFQPTIRKASTNQYRAFKPLESDADKYNDVIEDESDDDNMSTDEAKNRKEEKKNVNMKKETKPSNKDIDDKSNG-----------------WFGWLKKDTGDKKVYKAKLGHKNTLYYDEKLKRWVNKDATEEEKQKIIESSAPPPPPIVKRKDGGPKTKPRSGPINNSLPPVHATSVIPNNPITGEPLPIKTSPSPTGPNPNNSPSPS--------------------------------------------------------------SPISRISGVNLTSKKANGLDDLLSLAGGPKPASTRRKKKTARGYVNVMDNIQ-----------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : : : * : :. . . . . : * : . . : * . : * : .:.: .* .: . . . . .: . * .::: : : . * : . :: ..* :. : . . * . : . * * : . : : .:* : : .* . *... . : .: . : :. : . .. : . : : .:: . . . . . . ", "identical_positions": 14, "similar_positions": 94, "identity": "0.52%" }, { "cls_id": "homologset.agr.SGD:S000006007", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACM1-1", "uniprot_id": "D4ACM1_RAT", "id": "D4ACM1-1", "name": "Elongator complex protein 3", "aln": "----MKQKRKG--DLSPA-ELMMLTIGDVIKQLVEAHEQG--KDVDLNNAKCFAFRLKTKTASKYGLSSQPRLVDIIAAVPPHYRKILIPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAIKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQFIEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYRSYSPSDLIELVARILALVPPWTRVYRVQRDIPMPLVSSGVDHGNLRELAFARMKDLGIQCRDVRTREVGIQEIHHRVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEE-TFRFELGGG-VSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIALEEHGSGKIAVISGVGTRNYYRKMGYRLQGPYMVKMLK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CZX0-1", "uniprot_id": "ELP3_MOUSE", "id": "Q9CZX0-1", "name": "Elongator complex protein 3", "aln": "----MRQKRKG--DLSPA-ELMMLTIGDVIKQLVEAHEQG--KDVDLN-------KMKTKTAAKYGLASQPRLVDIIAAVPPHYRKILIPKLKAKPVRTASGIAVVAVMCKPHRCPHISFTGNICIYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRSLHDALSGHTSNNIHEAIKYSERSFTKCVGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAACESFHLAKDSGFKVVTHMMPDLPNVGLERDIEQFIEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYRSYSPSDLIELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELAFARMKDLGIQCRDVRTREVGIQEIHHRVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEE-TFRFELGGG-VSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKMAVISGVGTRNYYRKIGYRLQGPYMVKMLK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H9T3-1", "uniprot_id": "ELP3_HUMAN", "id": "Q9H9T3-1", "name": "Elongator complex protein 3", "aln": "----MRQKRKG--DLSPA-ELMMLTIGDVIKQLIEAHEQG--KDIDLN-------KVKTKTAAKYGLSAQPRLVDIIAAVPPQYRKVLMPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEE-TFRFELGGG-VSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGPYMVKMLK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RIC0-1", "uniprot_id": "ELP3_DANRE", "id": "Q5RIC0-1", "name": "Elongator complex protein 3", "aln": "---MGKPKKKS--DLSRA-ELMMMTIADVIKQLVEAHEEG--KDINLN-------KVKTKTSAKYGLSAQPRLVDIIAAVPPHYRRALVPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYLQTRHRVEQLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNVTEAVRYSERSNTKCVGITIETRPDYCLKRHLSDMLGYGCTRLEIGVQSVYEDVARDTNRGHTVRAVCESFHLAKDAGFKVVAHMMPDLPNVGMERDVEQFIEFFENPAFRPDGLKLYPTLVIRGTGLYELWKTGRYKSYSPSALVDLVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDMGTECRDVRTREVGIQEIHHKVRPYQVELIRRDYVANGGWETFLSYEDPEQDILIGLLRLRRCSPQ-SFRPELKGG-VSIVRELHVYGSVVPVSSRDPSKFQHQGFGMMLMEEAERIARDEHGSSKLAVISGVGTRNYYRKMGYELEGPYMVKNLY---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQZ6-1", "uniprot_id": "ELP3_DROME", "id": "Q9VQZ6-1", "name": "Elongator complex protein 3", "aln": "----MKAKKKLGVGLSRQ-ERQVLVIGEIIQELLKAHEAK--KDVNLN-------RMKSLVASKYGLDSSPRLVDIIAAVPQDAKKILLPKLRAKPIRTASGIAVVAVMCKPHRCPHINMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRSRYDPFLQTRHRVEQLKQLGHSVDKVEFIVMGGTFMCLPEEYRDYFIRNLHDALSGHSSANVAEAVRYSEKSRTKCIGITIETRPDYCLKRHISDMLSYGCTRLEIGVQSVYEDVARDTNRGHTVRAVCESFQLGKDAGYKIVTHMMPDLPNVDFERDIEQFIEYFENPAFRSDGLKIYPTLVIRGTGLYELWKTGRYKSYPPSMLVDLVAKILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGTTCRDVRTREVGIQEIHNKVRPYEIELIRRDYVANGGWETFLSYEDPEQDILVGLLRLRKCSPD-TFRPELKGE-CSIVRELHVYGSVVPVNARDPTKFQHQGFGMLLMEEAERIAREEHGSTKLAVISGVGTRNYYRKMGYQLDGPYMSKSIEENN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02908-1", "uniprot_id": "ELP3_YEAST", "id": "Q02908-1", "name": "Elongator complex protein 3", "aln": "MARHGKGPKTNKKKLAPEKERFIQCCADITLELTDSLTSGTTREINLN-------GLITKYSKKYKLKQQPRLTDIINSIPDQYKKYLLPKLKAKPVRTASGIAVVAVMCKPHRCPHIAYTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYEQARGRVEQLKQLGHSIDKVEYVLMGGTFMSLPKEYREDFIVKLHNALSGFNGNDIDEAILYSQQSLTKCVGITIETRPDYCTQTHLDDMLKYGCTRLEIGVQSLYEDVARDTNRGHTVRSVCETFAVSKDAGYKVVSHMMPDLPNVGMERDIEQFKEYFENPDFRTDGLKIYPTLVIRGTGLYELWKTGRYKSYSANALVDLVARILALVPPWTRIYRVQRDIPMPLVTSGVDNGNLRELALARMKDLGTTCRDVRTREVGIQEVHHKVQPDQVELIRRDYYANGGWETFLSYEDPKKDILIGLLRLRKASKKYTYRKEFTSQRTSIVRELHVYGSVVPLHSRDPRKFQHQGFGTLLMEEAERIAKEEHGSEKISVISGVGVRNYYGKLGYELDGPYMSKRI----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. *: * : .:: :* .: ::::** : : : ** * .***.*** ::* . :: *:***:***:********************* *****:*****************************:****: *:* *:*********:****:::******.**:***: ** .**:****... :: **: **::* ***:*********** : *:.*** ************:**************::.**:* :.**:*:*:*:*********.:***:*** *:**** **.****:****************:***:**... *::***:**********:************:***::*******:*****:* *************:*::*:* ::**:**** **************.:***:******:.* . ::* *: . **************: :*** ******** :********* :**** *::******.**** *:**.*:**** * : ", "identical_positions": 368, "similar_positions": 113, "identity": "64.79%" }, { "cls_id": "homologset.agr.SGD:S000006008", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D099-1", "uniprot_id": "ACER3_MOUSE", "id": "Q9D099-1", "name": "Alkaline ceramidase 3", "aln": "---------MAPAVDRKGYWGPTTSTLDWCEENYVVTLFVAEFW----------------------------NTVSNLIMIIPP--IFGAIQGIRDRLEKRYIAAYLALTVVGMGSWCFHMTLKYEMQLLDELPMIYSCCIFVYCMFECFKTKSS------------INYHLLFTLFLYSLTVTTIYLKVKEPIFHQVMYGMLVFTLVLRSIYIVTWVYPWLRGLG------YTSLTVFLLGFLLWNIDNIFCDSLRNFR-KRVPPVLGVTTQFHAWWHILTGLGSYLHILFSLYTRTLYLRYRPKVKFLF--GIWPAVMFEPQRKH------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ADP7-1", "uniprot_id": "A0A8I6ADP7_RAT", "id": "A0A8I6ADP7-1", "name": "Alkaline ceramidase", "aln": "---------MAPAVDRKGYWGPTTSTLDWCEENYVVTLFVAEFCEWSLRRGARARAEGRRVENAEGEPGREGNTVSNLIMIIPP--IFGAIQGFRDRLEKRYIAAYVALTVVGMGSWCFHMTLKYEMQLLDELPMIYSCCIFVYCMFECFKTKSS------------INYHLLFTLVLFSLIVTTIYLKVKEPIFHQVMYGMLVFALVLRSIYIVTWVYPWLRGLG------YTSLTVFLLGFLLWNVDNIFCDSLRNFR-KTVPPVLGVATQFHAWWHILTGLGSYLHILFSLYTRTLYLRYRPKVKFLF--GIWPMVMFEPQRKH------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NUN7-1", "uniprot_id": "ACER3_HUMAN", "id": "Q9NUN7-1", "name": "Alkaline ceramidase 3", "aln": "---------MAPAADREGYWGPTTSTLDWCEENYSVTWYIAEFW----------------------------NTVSNLIMIIPP--MFGAVQSVRDGLEKRYIASYLALTVVGMGSWCFHMTLKYEMQLLDELPMIYSCCIFVYCMFECFKIKNS------------VNYHLLFTLVLFSLIVTTVYLKVKEPIFHQVMYGMLVFTLVLRSIYIVTWVYPWLRGLG------YTSLGIFLLGFLFWNIDNIFCESLRNFR-KKVPPIIGITTQFHAWWHILTGLGSYLHILFSLYTRTLYLRYRPKVKFLF--GIWPVILFEPLRKH------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P6A3-1", "uniprot_id": "A0A8M1P6A3_DANRE", "id": "A0A8M1P6A3-1", "name": "Alkaline ceramidase", "aln": "---------MAPAADRPGYWGTPTSTLDWCEENYVVSYYIAEFW----------------------------NTVSNLIMILPP--IYGAIQTCRDGLEVRYVWSFLGLAAVGIGSWSFHMTLQYEMQLLDELPMIYSCCVFVYCLYECFKQERA------------VNYFSIILLLTFSIIVSVIYLLWKEPVFHQVMYAVLVAFLVIRSVFIVTWVYPWLRALG------FTSLSVFLLGFVLWNIDNMMCDSLRSAR-QQLPPVVGAVTQLHAWWHILTGLGSYLHILLSLQIRSTYLKHRPKVKFLC--GVWPMLHIESQKAS------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02896-1", "uniprot_id": "YDC1_YEAST", "id": "Q02896-1", "name": "Alkaline ceramidase YDC1", "aln": "----MLFSWPYPEAPIEGYWGKPTSLIDWCEENYVVSPYIAEWS----------------------------NTITNSIFLMTA--FYSTYSAWRNKLETRYILIGMGFSLVGIGSWLFHMTLQYRYQLLDELPMLYATIIPSWSIFAETQEILIKDEKKRKESSFRIQMVISFIMCGIVTILTWIYVVVQKPAIFQVLYGILTLLVVVLSGWLTYYHVHDSFAKKNLFITMVMGMIPFVIGFICWQLDIHLCSFWIYIRRTYLALPLGVLLELHAWWHLLTGTGVYIFVVYLQYLRILTHGNPNDFLFIWRWGFFPELVRKGLPIGTSYSLEYLGPIVNTQVDDETKKNN", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VIP7-1", "uniprot_id": "ACASE_DROME", "id": "Q9VIP7-1", "name": "Inactive alkaline ceramidase", "aln": "MGGMGGGGLLDIYAMAWEHLRPGSSPVDWCEGNYLISSNIAEFV----------------------------NTFSNFLFILLPPVLIMLFKEYGRFVTPGIHVIWVLLIVVGLSSMYFHATLSLIGQLLDELAILWVFMAAFSLFYPKRYYPKFVK----------NDRKTFSWLMLLSAIAATGLSWWKPIVNAFVLMFMSVPTMVMLYTELQRVSDQRVYRLG------IRSTTVWAVAVFCWINDRIFCEAWSSINFPYLHGFWHIFIFIAAYTVLV--LFAYFYVESELPQRQPLLKYWPKNEFEFG---IPFISIRNPGKALRNTI-------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :* :**** ** :: :**: **.:* :::: . : . : : : **:.* ** **. ******.::: :: : : : : *: : . :*: : . : :... * * :*. . : : *: :: *:.: * . * * : . ", "identical_positions": 35, "similar_positions": 59, "identity": "9.97%" }, { "cls_id": "homologset.agr.SGD:S000006009", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43448-1", "uniprot_id": "KCAB3_HUMAN", "id": "O43448-1", "name": "Voltage-gated potassium channel subunit beta-3", "aln": "-----------------MQVSIACTEQNLRSR----------------------SSEDRLCGPRPGPGGGNGGPAGGGHGNPPGGGGSGPKARAALVPRP--------------------------------------------------------------------------------------PAPAGALRESTGRGTGMKYRNLGKSGLRVSCLGLGTWVTFGSQISDETAE------DVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSKGWRRSSYVITTKIFWGGQA------------------ETERGLSRKHIIEGLRGSLERLQLGYVDIVFANRSDPNCPM---------------EEIVRAMTYVINQGLALYWGTSRWGAAEIMEAYSMARQFNLIPPVCEQAEHHLFQREKVEMQLPELYHKIGVGSVTWYPLACGLITSKYDG-RVPDTCRASIKGYQWLKDKVQS---------------EDGKKQQAKVMDLLPVAHQLGCTVAQLAIAWCLRSEGVSSVLLGVSSAEQLIEHLGALQVLSQLTPQTVMEIDGLLGNKPHSKK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63494-1", "uniprot_id": "KCAB3_RAT", "id": "Q63494-1", "name": "Voltage-gated potassium channel subunit beta-3", "aln": "-----------------MQVSIACTEQNLRSR----------------------SSEDRLCGPRPGPGGGNGGPVGGGHGNPPGGGGLGSKSRTAVVPRP--------------------------------------------------------------------------------------PAPAGALRESTGRGTGMKYRNLGKSGLRVSCLGLGTWVTFGSQISDETAE------DLLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSKGWRRSSYVITTKIFWGGQA------------------ETERGLSRKHIIEGLQGSLDRLQLEYVDIVFANRSDPSSPM---------------EEIVRAMTYVINQGLALYWGTSRWSAAEIMEAYSMARQFNLIPPVCEQAENHFFQREKVEMQLPELYHKIGVGSVTWSPLACSLITSKYDG-QVPDACKATVKGYQWLKEKVQS---------------EDGKKQQARVTDLLPIAHQLGCTVAQLAIAWCLRSEGVSSVLLGVSSAEQLMEHLGSLQVLGQLTPQTVMEIDALLGNKSHSKK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97382-1", "uniprot_id": "KCAB3_MOUSE", "id": "P97382-1", "name": "Voltage-gated potassium channel subunit beta-3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRGYGLIFS-------------LKVVFTFLSLPHPP-----------------------------------------------------------------------------------------------GLQGSLDRLQLEYVDIVFANRSDPNSPM---------------EEIVRAMTYVINQGLALYWGTSRWSAAEIMEAYSMARQFNLIPPVCEQAENHFFQREKVEMQLPELYHKIGVGSVTWSPLACGLITSKYDG-RVPDTCKATVKGYQWLKEKVQS---------------EEGKKQQARVMDLLPTARQLGCTVGQLAIAWCLRSEGVSSVLLGVSSAEQLMEHLGSLQVLSQLTPQTVVEIDALLGNKSHSKK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62482-1", "uniprot_id": "KCAB2_MOUSE", "id": "P62482-1", "name": "Voltage-gated potassium channel subunit beta-2", "aln": "------------------------MYPESTTG--------------------SPARLS-LRQTGSPG-------MIYST-------RYGS------PKRQ-------------------------------------------------------------------------------------LQF----------------YRNLGKSGLRVSCLGLGTWVTFGGQITDEMAE------HLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIFWGGKA------------------ETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPM---------------EETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLIPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDS-GIPPYSRASLKGYQWLKDKILS---------------EEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNAEQLMENIGAIQVLPKLSSSIVHEIDSILGNKPYSKKDYRS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62483-1", "uniprot_id": "KCAB2_RAT", "id": "P62483-1", "name": "Voltage-gated potassium channel subunit beta-2", "aln": "------------------------MYPESTTG--------------------SPARLS-LRQTGSPG-------MIYST-------RYGS------PKRQ-------------------------------------------------------------------------------------LQF----------------YRNLGKSGLRVSCLGLGTWVTFGGQITDEMAE------HLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIFWGGKA------------------ETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPM---------------EETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLIPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDS-GIPPYSRASLKGYQWLKDKILS---------------EEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNAEQLMENIGAIQVLPKLSSSIVHEIDSILGNKPYSKKDYRS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13303-1", "uniprot_id": "KCAB2_HUMAN", "id": "Q13303-1", "name": "Voltage-gated potassium channel subunit beta-2", "aln": "------------------------MYPESTTG--------------------SPARLS-LRQTGSPG-------MIYST-------RYGS------PKRQ-------------------------------------------------------------------------------------LQF----------------YRNLGKSGLRVSCLGLGTWVTFGGQITDEMAE------QLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIFWGGKA------------------ETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPM---------------EETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDS-GIPPYSRASLKGYQWLKDKILS---------------EEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNADQLMENIGAIQVLPKLSSSIIHEIDSILGNKPYSKKDYRS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GU13-1", "uniprot_id": "A0AC58GU13_DANRE", "id": "A0AC58GU13-1", "name": "Voltage-gated potassium channel subunit beta-1", "aln": "-----------------MFA---GGYAGGTVGRR------KSILPSENLQIPKPAGASGVRKSSSSSSGGKMLSMSYSESIRSGISRYHSDQGLNQPPRQT--DQAELQRLREQRVAA-----------------------------------------------------------QIKNMEDFLKMNGLALEECVSYQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAE------QLMTLAYENGINLFDTAEVYAAGKAEVVLGNVIKKKGWRRSSLVITTKIFWGGKA------------------ETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPM---------------EETVRAMTHVINQGMAMYWGTSRWSPMEIMEAYSVARQFNQIPPICEQSEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIISGKYDS-GVPPYSRASLKGYQWLKDKILS---------------EEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNTDQLMENIGAIQVLPKLSSSIVHEVDSILGNKPYSKKDYRS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B970-1", "uniprot_id": "A0A8M2B970_DANRE", "id": "A0A8M2B970-1", "name": "Voltage-gated potassium channel subunit beta-1", "aln": "-----------------MFATHRSSLTELRVGHTGRRLSRQHSVPSEQVPKNGPPGNS-VRRSSSISSS-KLLSLSFSESMRSDIDRYLSDQG-LYPLRQGGGEMGEIRSLREVRAAA-----------------------------------------------------------QLKNLEDFLRSNGVSLQESISFQTGMRYRNLGKSGLRVSCLGLGTWVTFGGQITDEIAE------QLMTLAYENGINLFDTAEVYAAGKAEMVLGSIIKKKGWRRSSLVITTKIYWGGKA------------------ETERGLSRKHIIEGLRASLERLQLEYVDVVFANRPDPNTPMEGDPFNTSKSRTFIIEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLIPPVCEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIISGKYDS-GVPPCSRASLKGYQWMKDKILS---------------EEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSCVLLGASSTDQLMENIGAIQVLPKLSSSIIHEVDSILGNKPYSKKDYRS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P63143-1", "uniprot_id": "KCAB1_MOUSE", "id": "P63143-1", "name": "Voltage-gated potassium channel subunit beta-1", "aln": "-----------------MQVSIACTEHNLKS----------------------RNGEDRLLSKQSS----NAPNVVNAAR-----AKFRT----VAIIAR--------------------------------------------------------------------------------SLGTFTPQHHISLKESTAKQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAE------RLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKA------------------ETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPM---------------EEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGN-GVPESSRASLKCYQWLKERIVS---------------EEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63144-1", "uniprot_id": "KCAB1_RAT", "id": "P63144-1", "name": "Voltage-gated potassium channel subunit beta-1", "aln": "-----------------MQVSIACTEHNLKS----------------------RNGEDRLLSKQSS----TAPNVVNAAR-----AKFRT----VAIIAR--------------------------------------------------------------------------------SLGTFTPQHHISLKESTAKQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAE------RLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKA------------------ETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPM---------------EEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGN-GVPESSRASLKCYQWLKERIVS---------------EEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9PRF1-1", "uniprot_id": "A0A8M9PRF1_DANRE", "id": "A0A8M9PRF1-1", "name": "Voltage-gated potassium channel subunit beta-1", "aln": "-----------------MQVSFACTDHGLKA----------------------PRTSE--PNKQNT----SSPNTASAAR-----ARFRT----VALIAR--------------------------------------------------------------------------------SLGSFTHRHHISLKESTGKLTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAE------QLMTIAYENGVNLFDTAEVYSAGKAEIILGNIIKKKCWRRSSLVITTKLYWGGKA------------------ETERGLSRKHIIEGLKGSLQRLQLDYVDVVFANRPDSNTPM---------------EEIVRAMTHVINHGMSMYWGTSRWSAMEIMEAYSVARQFNLIPPVCEQAEYHLFQRDKVEMQLPELYHKIGVGVVSWSPLACGIITGKYEN-GIPESSRASMKSYQWLKEKILG---------------EDGRKQQAKLKELTHIAERLSCTLPQLAIAWCLRNEGVSSVLLGTSNPAQLTENLGAIQVLPKITAHVASDIDKILGNRPHSKKDYHH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q14722-1", "uniprot_id": "KCAB1_HUMAN", "id": "Q14722-1", "name": "Voltage-gated potassium channel subunit beta-1", "aln": "-------MLAARTGAAGSQISEENTKLRRQSG-------------------FSVAGKDKSPKKASENAKDSSLSPSGESQ-----LRARQ----LALLREV-------------------------------------------------------------------------------EMNWYLKLCDLSSEHTTVCTTGMPHRNLGKSGLRVSCLGLGTWVTFGGQISDEVAE------RLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKA------------------ETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPM---------------EEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGN-GVPESSRASLKCYQWLKERIVS---------------EEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PHI0-1", "uniprot_id": "M9PHI0_DROME", "id": "M9PHI0-1", "name": "", "aln": "MSMALCNLNGDGSAAQSTSQSQSQSPAATAAAAPLLPHSHSHTLQPESTPLLLGHEQSGSAAPEGSGGGDVTDGAVTSIEMPTVVADDAGVPPLPLPLPQSTPQPLLMALPANLNFITGPTTQQLMIGNGAMGVIPSTNDSNNNNNNNNNVDNTSDESNPVTIYRCRAPIASLDCMEEFSRSISLGSNPALPLRHGSTPTPGLRYKNLGKSGLRISNVGLGTWPVFSPGVSDDQAE------AILKLAIESGINLFDISEAHS----ETEIGKILQRAGWKRTAYVITTKVYWSTKS------------------E-ERGLSRKHIIECVRASLQRLQLQYIDIVIIHKADPMCPM----------------EVVRAMSYVIQQGWAMYWGTARWSQVEIMEAYTNCRQFNCITPIVEQSEYHMFCREKCELYLPEMYNKIGVGLMAWGPLSMALSDTQNGDKLFLPKGSFKTKSFSWTEDEINRNAALSPQGSWGKDRIDEGRRHCDRLRDLAALAEKLGCSPTQLSIAWSLKHEPVQCLLLGATSAEQLHQSLQSLQLLPRLSSSVMLELERILENKPVRPPMISTLALRXQSACPQGPLSLSGGGPCGADSPKHEDEAFIEEVDAAKDAAKQGFCLIQXQKESLDNDNKFLKVISSKTSLSSNTMTTTISKQEQQQQQQQQQQQQHLQPQQYVQLQQQHLMASGSTSDSAAAVPIAAELQFDSLNNNNNNNNNNTNGSPEQALPTSDERQKRRSLLNFKSLDFHLKSLYSGLRSNSGTTPPSQPNSSVPAVDQPQRRMPYLRVESVDPEEPRGSVLPGHSPSFLSPYSGVGGGAGSLQLPSNDGGTIRRSSTSDIVNCRRGGGAGGSGGGAASAQDSRRPSTSDLLRKARERKGSEARMGRSVSHSGLTRGGPGGGGGGLGGRRTSMAF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02895-1", "uniprot_id": "AAD16_YEAST", "id": "Q02895-1", "name": "Putative aryl-alcohol dehydrogenase AAD16", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLVKQVRLGNSGLKISPIVIGCMSYGSKKWADWVIEDKTQIFKIMKHCYDKGLRTFDTADFYSNGLSERIIKEFLEYYSIKRETVVIMTKIYFPVDETLDLHHNFTLNEFEELDLSNQRGLSRKHIIAGVENSVKRLG-TYIDLLQIHRLDHETPM---------------KEIMKALNDVVEAGHVRYIGASSMLATEFAELQFTADKYGWFQFISSQSYYNLLYRE-DERELIPFAKRHNIGLLPWSPNARGMLTRPLNQ------STDRIKSDPTFKSLHLD---------------NLEEEQKEIINRVEKVSKDKKVSMAMLSIAWVLHKG--CHPIVGLNTTARVDEAIAALQVT-------LTEEEIKYLEEPYKPQRQRC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. *:.** *:*:: :: * ** * ::*:. *:: * * *:: *: * . ::. : .*: ::: *: * * : :: .:* :.* * : .: * :. : ..: : : :. : *::** *: ::* ... :: : : ::*: : : :.. ", "identical_positions": 30, "similar_positions": 71, "identity": "3.22%" }, { "cls_id": "homologset.agr.SGD:S000006010", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MJY4-1", "uniprot_id": "MEF2C_RAT", "id": "A0A096MJY4-1", "name": "Myocyte-specific enhancer factor 2C", "aln": "MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNSDIVETLR--------------------------------------------KKGLNGCDSPDPDADDSVGHSPESEDKYRKINEDIDL-MISRQRLCA----------------------------VPPPNFEMPVTIPVSSHNSLVYSNPVSSLGNPNLLP---------LAHP------SLQRNSMSPGVTHRPPSAGNTGGLMGG---DLTSGAGTSAG---------NGYGNPRNSPGLLVSPG--NLNKNIQAKSPP----PMNLGMNNRKPDLRVLIPPGSKNTMPSVSEDVD------LLLNQRINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTTYGTEYSLSSADLSSLSGFNTASALHLGSVTGWQQQHLHNMPP-----------------------------------------SALSQLGACTSTHLSQSS-------NLSLPSTQSLNIKSEPVSPPRDRTTT--PSRYP-----QHT---------------RHEAGRSPVDSLSS-CSSSYDGSDREDHRNEFHSPIGLTRPSP---DERESPSVKRMRLSEG-WAT------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CFN5-1", "uniprot_id": "MEF2C_MOUSE", "id": "Q8CFN5-1", "name": "Myocyte-specific enhancer factor 2C", "aln": "MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNSDIVETLR--------------------------------------------KKGLNGCDSPDPDADDSVGHSPESEDKYRKINEDIDL-MISRQRLCA----------------------------VPPPSFEMPVTIPVSSHNSLVYSNPVSTLGNPNLLP---------LAHP------SLQRNSMSPGVTHRPPSAGNTGGLMGG---DLTSGAGTSAG---------NGYGNPRNSPGLLVSPG--NLNKNIQAKSPP----PMNLGMNNRKPDLRVLIPPGSKNTMPSVSEDVD------LLLNQRINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTTYGTEYSLSSADLSSLSGFNTASALHLGSVTGWQQQHLHNMPP-----------------------------------------SALSQLGACTSTHLSQSS-------NLSLPSTQSLSIKSEPVSPPRDRTTT--PSRYP-----QHTT--------------RHEAGRSPVDSLSS-CSSSYDGSDREDHRNEFHSPIGLTRPSP---DERESPSVKRMRLSEG-WAT------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06413-1", "uniprot_id": "MEF2C_HUMAN", "id": "Q06413-1", "name": "Myocyte-specific enhancer factor 2C", "aln": "MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNSDIVETLR--------------------------------------------KKGLNGCDSPDPDADDSVGHSPESEDKYRKINEDIDL-MISRQRLCA----------------------------VPPPNFEMPVSIPVSSHNSLVYSNPVSSLGNPNLLP---------LAHP------SLQRNSMSPGVTHRPPSAGNTGGLMGG---DLTSGAGTSAG---------NGYGNPRNSPGLLVSPG--NLNKNMQAKSPP----PMNLGMNNRKPDLRVLIPPGSKNTMPSVSEDVD------LLLNQRINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTTYGTEYSLSSADLSSLSGFNTASALHLGSVTGWQQQHLHNMPP-----------------------------------------SALSQLGACTSTHLSQSS-------NLSLPSTQSLNIKSEPVSPPRDRTTT--PSRYP-----QHT---------------RHEAGRSPVDSLSS-CSSSYDGSDREDHRNEFHSPIGLTRPSP---DERESPSVKRMRLSEG-WAT------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B3N7-1", "uniprot_id": "A0A8M3B3N7_DANRE", "id": "A0A8M3B3N7-1", "name": "", "aln": "MGRKKIQIARIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNSDIVETLR--------------------------------------------KKGLNGCDSPDIDAEDS-GHSPESEDKYRKINEDIDL-MISRQRLCA----------------------------IPQSNYDMPVSIPVSNPNSLIYGHPGASLGNPNLLP---------LTHP------SLQRNSMSPGVTHRPPSAGNTGGLMAA---DLGSGAGTSTG---------NGYGNHRNSPGLLVSPG--NMSKNLQAKSPP----SMNMSLS-RKPDLRVLIPPGAKNTMPSISEDVD------MLLNQRISSSQSAQSLSTPVVSVATPTLPGEVMGGYPSAINTSYGTEYSLSSGDLSSLSAFNSSASLHLGSMTGWP----QNMQH-----------------------------------------SGLGHLGNCSSAQLCQSS-------ALSLPSNQNLHIKSEPVSPPRDRASG-TPGLYG-VP--QQTP-------------LRQDSGRSPVDSLSS-CGSSYDGSDRDEHRANFHSPVGLMRAAE---NERQSPSVKRMRLSEAGWAS------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3B2S1-1", "uniprot_id": "A0A8M3B2S1_DANRE", "id": "A0A8M3B2S1-1", "name": "", "aln": "MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNSDIVETLR--------------------------------------------KKGLNGCDSPDPDADDSVGHSPESKDKYREINDDIDLHMISRQRICA----------------------------VPSSTYDM--TIPVNN---QIYP------GNHNLLP---------LAHH------GLQRNSMSPGVTHRPPSAG---GLMGT---DLSTGAGTSAGKDGIPTYYRNGYGNHRNSPGLLVSSG--GMNKSMQAKSPP----PVNLGMNSRKPDLRVLIPPGAKNNMPSISEDVD------LLLNQRINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTSYGTEYSLSSADLSSISGFNSANTLHLGSMSGWQQHQIQNMQH-----------------------------------------SALSQLGNCSSSHLCQGS-------NLSLPSTQSLHIKSEPVSPPRDRSSSTTPGGYGQLPSHQQHQG--------PTSQGRQDSGRSPADSLSS-CGSSHEGSDRDEHRPDFHSPLGLGRPGL---DDQDSPSIKRIRLSEG-WAT------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02078-1", "uniprot_id": "MEF2A_HUMAN", "id": "Q02078-1", "name": "Myocyte-specific enhancer factor 2A", "aln": "MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNSDIVEALN--------------------------------------------KKEHRGCDSPDP--DTSYVLTPHTEEKYKKINEEFDNMMRNHKIAPG----------------------------LPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSPPQ----TTLHRN-VSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVG--------NGFVNSRASPNLIGATGANSLGKVMPTKSPPP-PGGGNLGMNSRKPDLRVVIPPSSKGMMPPLSEEEE-L----ELNTQRISSSQATQPLATPVVSVTTPSLPPQGL--VYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQQ---HHLGQ-----------------------------------------AALSSL--VAGGQLSQGS-------NLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQQQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSS-SSSSYDGSDREDPRGDFHSPIVLGRPPN--TEDRESPSVKRMRMDA--WVT------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2MJT0-1", "uniprot_id": "MEF2A_RAT", "id": "Q2MJT0-1", "name": "Myocyte-specific enhancer factor 2A", "aln": "MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNSDIVEALN--------------------------------------------KKEHRGCDSPDP--DTSYVLTPHTEEKYKKINEEFDNMMRNHKIAPG----------------------------LPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLAESSMLSPPP----ATLHRN-VSPGAPQRPPSTGSAGGMLSTTDLTVPNGAGNGPVG--------NGFVDSRASPNLIGNTGANSVGKVMPTKSPPP-PGGGSVGMNSRKPDLRVVIPPSSKGMMPPLN-------------AQRISSSQATQPLATPVVSVTTPSLPPQGL--VYSAMPTAYNTDYSLTSADLSALQGFTSPGMLSLGQASAWQQ---HHLGQ-----------------------------------------AALSSL--VAGGQLSQGS-------NLSINTNQNINIKTEPISPPRDRMTPSGFQQQQQQQPQQQPPP----QPPQPQPQPRQEMGRSPVDSLSS-SSSSYDGSDREDPRGDFHSPIVLGRPPN--AEDRESPSVKRMRMDT--WVT------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60929-1", "uniprot_id": "MEF2A_MOUSE", "id": "Q60929-1", "name": "Myocyte-specific enhancer factor 2A", "aln": "MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNSDIVETLR--------------------------------------------KKGLNGCESPDA--DDYFEHSPLSEDRFSKLNEDSDFIFK--RGPPG----------------------------LPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLADSSMLSPPP----ATLHRN-VSPGAPQRPPSTGSASGMLSTTDLTVPNGAGNSPVG--------NGFVNSRASPNLIGNTGANSLGKVMPTKSPPP-PGGGSLGMNSRKPDLRVVIPPSSKGMMPPLSEEEE-L----ELNAQRISSSQATQPLATPVVSVTTPSLPPQGL--VYSAMPTAYNTDYSLTSADLSALQGFTSPGMLSLGQASAWQQ---HHLGQ-----------------------------------------AALSSL--VAGGQLSQGS-------NLSINTNQNINIKSEPISPPRDRMTPSGFQQQQQQ-PQQQPPP------QPPQPQPRQEMGRSPVDSLSS-SSSSYDGSDREDPRGDFHSPIVLGRPPN--TEDRESPSVKRMRMDT--WVT------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32T6Z3-1", "uniprot_id": "A0AB32T6Z3_DANRE", "id": "A0AB32T6Z3-1", "name": "", "aln": "MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNSDIVEKLRNKGHNDCPSPDPDDCFGHSPLMDDRFGKLNEESDLMYKRCGALNKKEHRGCDSPDP--DASYVLTPHTEEKYKKINEEFDNMMRNHKIPTA----------------------------LPPQNFSMHVAVPVTNPNAMSY-NPGASLSSQSLSAAASLSDGAMLSPPQ----GSMHRS-VVP--PQRPPSTG-------------------STAG--------NGFVNPRGSPGLLGTPSGNGLGKVMPAKSPPP-PGG-NMGIGSRKPDLRVVIPPSSKGMMPPLQSEEEEM----ELNTQRISSSQSTQPLATPVVSVTTPSLAPQGL--VYSGMPTAYNSEYSLSSAELSSLQGFGSPG-LSIGSVSAWQQ---HQLGQ-----------------------------------------AALSSL--VGGGHLPQGS-------NLSINTSQNVNIKSEPISPPRERVTPSGFPPQQQQ-----------------PPSGRPDMGRSPVDSLSS-SCSSYDGSDREDHRPDFHSPLGLGRPPAGGADERESPSVKRMRMDT--WVT------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q63943-1", "uniprot_id": "MEF2D_MOUSE", "id": "Q63943-1", "name": "Myocyte-specific enhancer factor 2D", "aln": "MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNADIIETLR--------------------------------------------KKGFNGCDSPEPDGEDSLEQSPLLEDKYRRASEELDG--LFRRYGSS----------------------------VPAPNFAMPVTVPVSNQSSMQFSNPSSSLVTPSLVTSS-LTDPRLLSPQQ----PALQRNSVSPGLPQRPASAG---AMLGG-DLNSANGACPSPVG--------NGYVSARASPGLLPVANGNSLNKVIPAKSPPPPTHNTQLGAPSRKPDLRVITSQGGKGLMHHLTEDHL-D----LNNAQRLGVSQSTHSLTTPVVSVATPSLLSQGLP--FSSMPTAYNTDYQLPSAELSSLPAFSSPAGLALGNVTAWQQPQPPQQPQPPQPPQ-----------------SQPQPPQPQ----PQQPPQQQPHLVPVSLSNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVF------------------------PAARPEPGEGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAP--EPEAEGSAVKRMRLDT--WTLK-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O89038-1", "uniprot_id": "MEF2D_RAT", "id": "O89038-1", "name": "Myocyte-specific enhancer factor 2D", "aln": "MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNADIIETLR--------------------------------------------KKGFNGCDSPEPDGEDSLEQSPLLEDKYRRASEELDG--LFRRYGSS----------------------------VPAPNFAMPVTVPVSNQSSMQFSNPSSSLVTPSLVTSS-LTDPRLLSPQQ----PALQRNSVSPGLPQRPASAG---AMLGR-DLNSANGACPNPVG--------NGYVSARASPGLLPVANGNGLNKVIPAKSPPPPTHNTQLGAPSRKPDLRVITSQGGKGLMHHL------------NNAQRLGVSQSTHSLTTPVVSVATPSLLSQGLP--FSSMPTAYNTDYQLPSAELSSLPAFSSPAGLALGNVTAWQQPQQPQQPQPPQPPQ-----------------SQPQPPQPQ----PQQPPQQQPHLVPVSLSNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVF------------------------PAARPEPGEGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAP--EPEAEGSAVKRMRLDT--WTLK-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14814-1", "uniprot_id": "MEF2D_HUMAN", "id": "Q14814-1", "name": "Myocyte-specific enhancer factor 2D", "aln": "MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNADIIETLR--------------------------------------------KKGFNGCDSPEPDGEDSLEQSPLLEDKYRRASEELDG--LFRRYGST----------------------------VPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSS-LTDPRLLSPQQ----PALQRNSVSPGLPQRPASAG---AMLGG-DLNSANGACPSPVG--------NGYVSARASPGLLPVANGNSLNKVIPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHL-D----LNNAQRLGVSQSTHSLTTPVVSVATPSLLSQGLP--FSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVTAWQQPQQPQQPQQPQPPQQ--------------QPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVF------------------------PAARPEPGDGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAP--EPEAEGSAVKRMRLDT--WTLK-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O55087-1", "uniprot_id": "MEF2B_MOUSE", "id": "O55087-1", "name": "Myocyte-specific enhancer factor 2B", "aln": "MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVLLKY-------------TEYSEPHESRTNADILQTLK--------------------------------------------RRGV-GLDGPELDMEEGPEGPGEKLLR--TLGGDRGSASPRPRIYPV----------------------------APAMSVSE----------LSYRVPPATPGCDPGGLG-------------------------EVPSVHSRPAYFR------------------------------PPGLGHPIFSPSHLAS------------KTPPP----LYLATDGRRPDL----PPGLVGARGGLG---------------------TSRSLYSGLQ---SPGAPGPA-----------LGS-FAFLPS------------------------------------------------------------------------GSTDCSPGDAAQGPLQPSP---------WPPTRDAV----DPARPVARSLCKEGPPSRG------------------------ASPPTPPVSIKS--ERLSPVTGTSGDFPRSFPYPLLLARPLA---EP-LRPSASLHRLTPDSWPR------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7EZT3-1", "uniprot_id": "F7EZT3_RAT", "id": "F7EZT3-1", "name": "", "aln": "MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVLLKY-------------TEYSEPHESRTNADILQTLK--------------------------------------------RRGV-GLDGPELDMEEGPEGPGEKLLR--TLGGDRGLVSPPPRIYPV----------------------------APAMSVSE----------LSYRVPPATSGCDPGGLG-------------------------EAPSVHSRSPHFR------------------------------PPGLGHPIFSPSHLAG------------KTPPP----LYLATDGRRPDL----PPGLVGARGGLG---------------------TSRSLYSGLQ---SPGAPGPA-----------LGS-FAFLPP------------------------------------------------------------------------GSADCSPGDAAQVPLQPSP---------WPPTRDAV----DPAGPAARSLCEEGPPSRE------------------------ASPPTPPVSIKS--ERLSPVTGTSGDFPRSFPYPLLLARPLA---EP-LRP-ASLRRLTPDSWPR------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02080-1", "uniprot_id": "MEF2B_HUMAN", "id": "Q02080-1", "name": "Myocyte-specific enhancer factor 2B", "aln": "MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYASTDMDRVLLKY-------------TEYSEPHESRTNTDILETLK--------------------------------------------RRGI-GLDGPELEPDEGPEEPGEKFRR--LAGEGGDPALPRPRLYPA----------------------------APAMPSPD----------VVYGALPP-PGCDPSGLG-------------------------EALPAQSRPSPFRPAAPK---------------AG--------PPGLVHPLFSPSHLTS------------KTPPP----LYLPTEGRRSDL----PGGLAGPRGGLN---------------------TSRSLYSGLQNPCSTATPGPP-----------LGS-FPFLPG------------------------------------------------------------------------GPP---VGAEAWARRVPQP---------AAPPRRPP----QSASSLSASLRPPGAPATF------------------------LRPSPIPCSSPGPWQSLCGLGPPCAGCPWPTAGPGRRSPGGT---SPERSPGTARARGDPTSLQASSEKTQQ-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IEL7-1", "uniprot_id": "A0AC58IEL7_DANRE", "id": "A0AC58IEL7-1", "name": "", "aln": "MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNRLFQYASTDMDKVLLKY-------------TEYSEPHESRTNTDILETLR--------------------------------------------RKGL-GLESSEIDPEDGVTMGAEKYHDGMDLSLARQRYYAPSLLHSE----------------------------VINTSAENGYINSSNPNLGAHRTPSYKPLCTRPGST-------------------------GTVSANSHPALMGPHADTNLY----------NDIG--------DTGLGYSMFPHGSLSRAL--------EMKTPPP----LNMSSDGRRVEA----HAGLCGTRSSLANAVR---------------ESTKRALYQSMHAGGHMMAMGKTGL---------LGHGLNYSPSEYSHPGYTVGFQRSSMNTWQPLTHQDAHQSMI----------------------------------------SPGMASGGSCSYPSQSSSP---------SSPSHPSLNLSIKSERTSPVHMISPTPPSHH------------------------MLQHSPIAEPKS---SSCPPSDEYADLQREEAQKSSFSGQQQ---GPNRDPPETKSSPNPKQQDISNGWIR------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40791-1", "uniprot_id": "MEF2_DROME", "id": "P40791-1", "name": "Myocyte-specific enhancer factor 2", "aln": "MGRKKIQISRITDERNRQVTFNKRKFGVMKKAYELSVLCDCEIALIIFSSSNKLYQYASTDMDRVLLKY-------------TEYNEPHESLTNKNIIEKEN--------------------------------------------KNGVMSPDSPEA--ETDYTLTPRTEAKYNKIDEEFQNMMQRNQMAIGGAGAPRQ---------------------LPNSSYTLPVSVPVPGSYGDNLLQASPQMSHTNISPRPSSSETDSGGMSL----IIYPSGSMLEMSNGYPHSHSPLVGSPSP---------GPSPGIAHHLSIKQQSPGSQNGRASNLRVVIPPTIAPIPPNMSAPDDVGYADQRQSQTSLNTPVVTLQTPIPALTSYSFGAQDFSSSGVMNSADIMSLNTWHQGLVPHSSLSHLAVSNSTPPPATSPVSIKVKAEPQSPPRDLSASGHQQNSNGSTGSGGSSSSTSSNASGGAGGGGAVS--------------AANVITHLNNVSVLAGGPSGQGGGGGGGGSNGNVEQATN-------LSVLSHAQQHHLGMPNSRPSSTGHITPTPGHDKYEG----------------YPYRALMGHNPRWNLNFAGAPSSDQDVRLAAVAVQQQQQQPHQQQQ--LGDYDAPNHKRPRISGG-WGT------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12224-1", "uniprot_id": "RLM1_YEAST", "id": "Q12224-1", "name": "Transcription factor RLM1", "aln": "MGRRKIEIQRISDDRNRAVTFIKRKAGLFKKAHELSVLCQVDIAVIILGSNNTFYEFSSVDTNDLIYHYQNDKNLLHEVKDPSDYGDFHKSASVNINQDLLRSSMSNK------------------------------------PSKSNVKGMNQSENDDDENNDEDDDDHGNFERNSNMHSNKKASDKNIPSAHMKLLSPTALISKMDGSEQNKRHPENALPPLQHLKRLKPDPLQISRTPQQQQQQNISRPYHSSMYNLNQPSSSSSSPSTMDFPKLPSFQNSSFNGRPPPISISPNKFSKPFTNASSRTPKQEHKINNSGSNNNDNSNYTQSPSNSLEDSIQQTVKARRKLSARP---VLRVRIPNNNFSSNSAIPSEPSSASSTSANGNSMGSSQIMKENKTSRSSKISPLSASASGPLTLQKGNNGRMVIKLPNANAPNGSNNGNGSNNNNHPYPFGSGSSPLFSATQPYIATPLQPSNIPGGPFQQNTSFLAQRQTQQYQQMSFKKQSQTVPLTTTLTGRPPSTFSGPETSNGPPTGSLPSKFVHDLMSNSPNVSSISMFPDWSMGPNSAKPGNTNNPGTFPPVQTAVNNGNSSNISSTNNTNNNNNNNNNNSSNNNSNNGNDNNSNNSNNSYYSNNEDAPVNGAAISEHTTDGDSNNQSNSSTYDAAATAYNGNTGLTPYINTAQTPLGTKFFNFSTDISGEKNSSKI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:**:* ** *:*** *** *** *::***:******: :**:**:. : :::::* * : :: :* ::*.: *:* : : . : . : .: : . . . . :. . . . . . . ", "identical_positions": 38, "similar_positions": 47, "identity": "5.31%" }, { "cls_id": "homologset.agr.SGD:S000006011", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62753-1", "uniprot_id": "RS6_HUMAN", "id": "P62753-1", "name": "Small ribosomal subunit protein eS6", "aln": "MKLNISFPATGCQKLIEVDDERKLRTFYEKRMATEVAADALGEEWKGYVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKRKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPRRLGPKRASRIRKLFNLSKEDDVRQYVVRKPLN-KEGKKPRTKAPKIQRLVTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62754-1", "uniprot_id": "RS6_MOUSE", "id": "P62754-1", "name": "Small ribosomal subunit protein eS6", "aln": "MKLNISFPATGCQKLIEVDDERKLRTFYEKRMATEVAADALGEEWKGYVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKRKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPRRLGPKRASRIRKLFNLSKEDDVRQYVVRKPLN-KEGKKPRTKAPKIQRLVTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62755-1", "uniprot_id": "RS6_RAT", "id": "P62755-1", "name": "Small ribosomal subunit protein eS6", "aln": "MKLNISFPATGCQKLIEVDDERKLRTFYEKRMATEVAADALGEEWKGYVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKRKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPRRLGPKRASRIRKLFNLSKEDDVRQYVVRKPLN-KEGKKPRTKAPKIQRLVTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29327-1", "uniprot_id": "RS6_DROME", "id": "P29327-1", "name": "Small ribosomal subunit protein eS6", "aln": "MKLNVSYPATGCQKLFEVVDEHKLRVFYEKRMGQVVEADILGDEWKGYQLRIAGGNDKQGFPMKQGVLTHGRVRLLLKKGHSCYRPRRTGERKRKSVRGCIVDANMSVLALVVLKKGEKDIPGLTDTTIPRRLGPKRASKIRKLYNLSKEDDVRRFVVRRPLPAKDNKKATSKAPKIQRLITPVVLQRKHRRIALKKKRQIASKEASADYAKLLVQRKKESKAKREE--AKRRRSASIRESKSSVSSDKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX37-1", "uniprot_id": "RS6A_YEAST", "id": "P0CX37-1", "name": "Small ribosomal subunit protein eS6A", "aln": "MKLNISYPVNGSQKTFEIDDEHRIRVFFDKRIGQEVDGEAVGDEFKGYVFKISGGNDKQGFPMKQGVLLPTRIKLLLTKNVSCYRPRRDGERKRKSVRGAIVGPDLAVLALVIVKKGEQELEGLTDTTVPKRLGPKRANNIRKFFGLSKEDDVRDFVIRREVT--KGEKTYTKAPKIQRLVTPQRLQRKRHQRALKVRNAQAQREAAAEYAQLLAKRLSERKAEKAE--IRKRRASSLKA----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:*:*..*.** :*: **:::*.*::**:. * .: :*:*:*** .:*:*************** *::***.*. ******* **********.**..:::** **::****::: ******:*:*******..***::.******** :*:*: : ..:*. :********:** **:*::: *** :. .:* :*:**:**.:* .* * :: * ::** :*:: ", "identical_positions": 127, "similar_positions": 76, "identity": "50.8%" }, { "cls_id": "homologset.agr.SGD:S000006012", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P47791-1", "uniprot_id": "GSHR_MOUSE", "id": "P47791-1", "name": "Glutathione reductase, mitochondrial", "aln": "---------MALLPRALGVGAAPSLRRAA-----------------RALTCAMASPGEPQPPAP----------------------------------------------DTSSFDYLVIGGGSGGLASARRAAELGARAAVVESH----------KLGGTCVNVGCVPKKVMWNTAVHSEFMHDHVDYGFQS------CEGKFSWHVIKQKRDAYVSRLNTIYQNNLTKSHIEIIHGYATFAD-GPRPTVEVNGKK---FTAPHILIATGGVPTVPHESQIPGASLGITSDGFFQLEDLPSRSVIVGAGYIAVEIAGILSALGSKTSLMIRHDKVLRNFDSLISSNCTEELENAG-VEVL---KFTQVKEVKKTSSGLELQVVTSVPGRK---PTTTMIPDVDCLLWAIGRDPNSKGLNLNKVGIQTDEKGHILVDEFQNTNVKGVYAVGDVCG-KALLTPVAIAAGRKLAHRLFECK--QDSKLDYDNIPTVVFSHPPIGTVGLTEDEAVHKYGKDNVKIYSTAFTPMYHAVTTRKTKCVMKMVCANK--EEKVVGIHMQGIGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P70619-1", "uniprot_id": "GSHR_RAT", "id": "P70619-1", "name": "Glutathione reductase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------VNVGCVPKKVMWNTAVHSEFIHDHVDYGFQN------CKSKFNWHVIKEKRDAYVSRLNNIYQNNLTKSHIEVIHGYATFRD-GPQPTAEVNGKK---FTAPHILIATGGVPTVPHENQIPGASLGITSDGFFQLEDLPSRSVIVGAGYIAVEIAGILSALGSKTSLMIRHDKVLRSFDSLISSNCTEELENAGGVEVLTVKKFSQVKEVKKTSSGLELHVVTALPGRK---PTVTTIPDVDCLLWAIGRDPNSKGLNLNKLGIQTDDKGHILVDEFQNTNVKGVYAVGDVCG-KALLTPVAIAAGRKLAHRLFEGK--EDSRLDYDNIPTVVFSHPPIGTVGLTEDEAVHKYGKDNVKIYSTAFTPMYHAVTTRKTKCVMKMVCANK--EEKVVGIHMQGIGCDEMLQGFAVAVKMGATKADFDNRVAIHPTSSEELVTLR----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00390-1", "uniprot_id": "GSHR_HUMAN", "id": "P00390-1", "name": "Glutathione reductase, mitochondrial", "aln": "---------MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAA-----------------------------------------GAVASYDYLVIGGGSGGLASARRAAELGARAAVVESH----------KLGGTCVNVGCVPKKVMWNTAVHSEFMHDHADYGFPS------CEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTS-DPKPTIEVSGKK---YTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAG-VEVL---KFSQVKEVKKTLSGLEVSMVTAVPGRL---PVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCG-KALLTPVAIAAGRKLAHRLFEYK--EDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANK--EEKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BHF6-1", "uniprot_id": "A0A8M2BHF6_DANRE", "id": "A0A8M2BHF6-1", "name": "Glutathione reductase", "aln": "---------MEILSPLARLRS--SFLSLG-----------------RSLSSSCKLLGRSMASGS-----------------------------------------------VSRFDFLVVGGGSGGLAGARRAAELGATTAVIESH----------RLGGTCVNVGCVPKKVMWNTSTHAEYLHDHEDYGFEG------AKAHFSWQIIKHKRDAYVSRLNQIYRSNLEKGKIEFIHGYARFTD-DPEPTVEVNGKK---YTATHILISTGGHPSTVSEDDVPGSSLGITSDGFFELESCPKRSVIVGAGYIAVEMAGILSTLGSKTSIIIRQGGVLRNFDALISSNCTKELQNNG-IDLR---KNTQVKSVKKNGKGLSITLVTKDPDDKDSQEKFDTINDVDCLLWAIGREPNTAGLNLSQIGVKLDERGHIVVDEFQNTSRPGVYAVGDVCG-RALLTPVAIAAGRKLAHRLFEGK--ADSKVDYNNIPTVVFSHPPIGTVGLTEDEAVKTYGKDKVKVYTTSFTPMYYAITSRKSQCIMKLVCAGE--NEKVVGLHMQGFGCDEMLQGFAVAVNMGATKADFDRTIAIHPTSSEELVTLR----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41921-1", "uniprot_id": "GSHR_YEAST", "id": "P41921-1", "name": "Glutathione reductase", "aln": "-----------MLS---------------------------------ATKQTFRSLQIRTMSTN-----------------------------------------------TKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAK----------ALGGTCVNVGCVPKKVMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNK-DGNVEVQKRDNTTEVYSANHILVATGGKAIFP--ENIPGFELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEG-INVH---KLSKIVKVEKNVETDKLKIHMN--DSK-------SIDDVDELIWTIGRK-SHLGMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVG-KVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGP--NEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR----------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VNT5-1", "uniprot_id": "TRXR2_DROME", "id": "Q9VNT5-1", "name": "Thioredoxin reductase 2, mitochondrial", "aln": "------MSTIKFLR--------------------------------SSTHNALRSSLGWCRLAASRP--------------------------------------------RYDYDLVVLGGGSAGLACAKEAAGCGARVLCFDYVKPTP-VGTKWGIGGTCVNVGCIPKKLMHQASLLGEAVHEAVAYGWNVDDTN----IRPDWRKLVRSVQNHIKSVNWVTRVDLRDKKVEYVNSMATFRDSHTIEYVAMPGAEHRQVTSEYVVVAVGGRPRYP--DIPGAVELGITSDDIFSYEREPGRTLVVGAGYVGLECACFLKGLGYEPTVMVR-SIVLRGFDRQMSELLAAMMTERGIPFLG----TTIPKAVERQADGRLLVRYRNTTTQMD------GSDVFDTVLWAIGRKGLIEDLNLDAAGVKTHD-DKIVVDAAEATSVPHIFAVGDIIYGRPELTPVAILSGRLLARRLFAGS---TQLMDYADVATTVFTPLEYSCVGMSEETAIELRGADNIEVFHGYYKPTEFFIPQKSVRHCYLKAVAEVSGDQKILGLHYIGPVAGEVIQGFAAALKTGLTVKTLLNTVGIHPTTAEEFTRLSITKRSGRDPTPASCCS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P91938-1", "uniprot_id": "TRXR1_DROME", "id": "P91938-1", "name": "Thioredoxin reductase 1, mitochondrial", "aln": "MNLCNSRFSVTFVRQCSTILTSPSAGIIQNRGSLTTKVPHWISSSLSCAHHTFQRTMNLTGQRGSRDSTGATGGNAPAGSGAGAPPPFQHPHCDRAAMYAQPVRKMSTKGGSYDYDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVGCIPKKLMHQASLLGEAVHEAAAYGWNVDEK-----IKPDWHKLVQSVQNHIKSVNWVTRVDLRDKKVEYINGLGSFVDSHTLLAKLKSG--ERTITAQTFVIAVGGRPRYP--DIPGAVEYGITSDDLFSLDREPGKTLVVGAGYIGLECAGFLKGLGYEPTVMVR-SIVLRGFDQQMAELVAASMEERGIPFLR----KTVPLSVEKQDDGKLLVKYKNVETGEE------AEDVYDTVLWAIGRKGLVDDLNLPNAGVTVQK-DKIPVDSQEATNVANIYAVGDIIYGKPELTPVAVLAGRLLARRLYGGS---TQRMDYKDVATTVFTPLEYACVGLSEEDAVKQFGADEIEVFHGYYKPTEFFIPQKSVRYCYLKAVAERHGDQRVYGLHYIGPVAGEVIQGFAAALKSGLTINTLINTVGIHPTTAEEFTRLAITKRSGLDPTPASCCS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****:***:* :: . : . ** .* : .. : :: :* : : :* . ::: : . . * . . :: .:::.** . . . . * **.:* : * : ::*****:.:* * .: ** :. :::* *** ** : : : * : : *:: . : * ::*:*** .:. *: .. .:* .* : *. ::::**: : *****: :** *:.**: . . :** ::.:.:*: . :*::*. *:. * :::: : :.. . : .. . * :::: *:* * . *::***..*:: * * : . :.****::**:. : ", "identical_positions": 84, "similar_positions": 139, "identity": "13.55%" }, { "cls_id": "homologset.agr.SGD:S000006014", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99P77-1", "uniprot_id": "GTPB4_RAT", "id": "Q99P77-1", "name": "GTP-binding protein 4", "aln": "MAHYNFKKITVVPSAKDFIDLTLSKTQRKTPTVIHKHYQIHRIRHFYMRKVKFTQQNYHDRLSQILSDFPKLDDIHPFYADLMNILYDKDHYKLALGQINIAKNLVDNVAKDYVRLMKYGDSLYRCKQLKRAALGRMCTIIKRQRQSLEYLEQVRQHLSRLPTIDPNTRTLLLCGYPNVGKSSFINKVTRADVDVQPYAFTTKSLFVGHVDYKYLRWQVVDTPGILDHPLEDRNTIEMQAITALAHLRAAVLYVMDLSEQCGHGLKEQLGLFQNIRPLFINKPLIVVASKCEVKRIAELSEEDQKIFLDLQAE-GFPVIETSTLTEEGVIQVKTEACDRLLAHRVETKMKGN-KVNEVLNRLHLAVPNKRDDKERPPFIPEGVVARRKR-MEIAEPKKKRERDLELEMGDD--YILDLQKYWDLMNSSEKYDKIPEIWEGHNAADYIDPAIMKKLEELEKGKKSSEQLLGSMPVSLRV------KTRKWWKIRQLAKQIR-EKK-KLKILQSKEKNTQGPRMPRTAKKVQR----ADLENEMRSLGVDMDDKDNAHY---AVRARRSRSVTRKRKREES----VPPSSIARSRSRSCSKTP-RDVSGLRDVKMVKKAKTMMK-KAQKKMNRLGKKGEADRHVFDMKPKHLLSGKRKAGKKERR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99ME9-1", "uniprot_id": "GTPB4_MOUSE", "id": "Q99ME9-1", "name": "GTP-binding protein 4", "aln": "MAHYNFKKITVVPSAKDFIDLTLSKTQRKTPTVIHKHYQIHRIRHFYMRKVKFTQQNYHDRLSQILSDFPKLDDIHPFYADLMNILYDKDHYKLALGQINIAKNLVDNVAKDYVRLMKYGDSLYRCKQLKRAALGRMCTIIKRQRQSLEYLEQVRQHLSRLPTIDPNTRTLLLCGYPNVGKSSFINKVTRADVDVQPYAFTTKSLFVGHMDYKYLRWQVVDTPGILDHPLEDRNTIEMQAITALAHLRAAVLYVMDLSEQCGHGLKEQLELFQNIRPLFINKPLIVVANKCDVKRIAELSEEDQKIFLDLQAE-GFPVIETSTLTEEGVIQVKTEACDRLLAHRVETKMKGN-KVNEVLNRLHLAVPNKRDDKERPPFIPEGVIARRKR-MEIEEPKKKRERDLELEMGDD--YILDLQKYWDLMNSSEKYDKIPEIWEGHNVADYIDPAIMKKLEELEK-EEELRTAAGEYDSDSES------EDEEMMEIRQLAKQIR-EKK-KLKILQSKEKNKQGPRMPRTAKKVQR----ADLENEMRSLGVDMDDKNNAHY---AVQARRSRSVTRKRKREES----VPPSSTARSRS--CSRTP-RDVSGLRDVKMVKKAKTMMK-KAQKKMNRLGKKGEADRHVFDMKPKHLLSGKRKAGKKDRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZE4-1", "uniprot_id": "GTPB4_HUMAN", "id": "Q9BZE4-1", "name": "GTP-binding protein 4", "aln": "MAHYNFKKITVVPSAKDFIDLTLSKTQRKTPTVIHKHYQIHRIRHFYMRKVKFTQQNYHDRLSQILTDFPKLDDIHPFYADLMNILYDKDHYKLALGQINIAKNLVDNVAKDYVRLMKYGDSLYRCKQLKRAALGRMCTVIKRQKQSLEYLEQVRQHLSRLPTIDPNTRTLLLCGYPNVGKSSFINKVTRADVDVQPYAFTTKSLFVGHMDYKYLRWQVVDTPGILDHPLEDRNTIEMQAITALAHLRAAVLYVMDLSEQCGHGLREQLELFQNIRPLFINKPLIVVANKCDVKRIAELSEDDQKIFTDLQSE-GFPVIETSTLTEEGVIKVKTEACDRLLAHRVETKMKGN-KVNEVLNRLHLAIPTRRDDKERPPFIPEGVVARRKR-METEESRKKRERDLELEMGDD--YILDLQKYWDLMNLSEKHDKIPEIWEGHNIADYIDPAIMKKLEELEK-EEELRTAAGEYDSVSES------EDEEMLEIRQLAKQIR-EKK-KLKILESKEKNTQGPRMPRTAKKVQR----TVLEKEMRSLGVDMDDKDDAHY---AVQARRSRSITRKRKREDS----APPSSVARSGS--CSRTP-RDVSGLRDVKMVKKAKTMMK-NAQKKMNRLGKKGEADRHVFDMKPKHLLSGKRKAGKKDRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V411-1", "uniprot_id": "NOG1_DROME", "id": "Q9V411-1", "name": "Nucleolar GTP-binding protein 1", "aln": "MSLYNFKKIMVVPPAKDFIDIMLSKTQRKTPTVVHKGYKISRIRAFYTRKVKYTQQNFHDRLSQIIQDFPKLDDVHPFYADLMNVLYDKDHYKLALGQLNTARHLVDNVAKDYVRLLKYGDSLYRCKQLKKAALGRMATIMKRQASNLTYLEQVRQHLSRLPTIDPYSRTIIICGFPNVGKSSFINKITRADVEVQPYAFTTKSLYVGHTDYKYLRWQVIDTPGILDHPLEERNVIEMQAITALAHLRACVLYFMDISEQCGHSLEEQVKLFESIKPLFTNKPLILAINKIDILTPEDLPEERRAIITKLQEDKNIPVMLMSTVQETGVMEVKTEACERLLSYRVDQKMRTK-KVDNILNRLHVAMPAPRDDKLRAPCIPEKASARLLQNADKAERKRKLEKEIEEEMGDD--YTLDLKKNYSEIPEEERYDIIPEFWQGHNIADYIDADIFDKLEELER-EEGLREESGVYKVPDMT------MDETLKEIREIAKQIR-GKRFELRDEKRLSSRKNKPVIPRNKQPKVRDRSVQKLVSTMEGLGVDMSGSENANFTKSVVDLRRGQVAVGSKKVPMQPLLDKESSAVVRKTGQPLKRAPSRDTLGIKNLAIRKKAQIMAKRDIAKKVTSRGLKGEADRFIGTKMPKHLFSGKRGNGKTDRR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02892-1", "uniprot_id": "NOG1_YEAST", "id": "Q02892-1", "name": "Nucleolar GTP-binding protein 1", "aln": "-MQLSWKDIPTVAPANDLLDIVLNRTQRKTPTVIRPGFKITRIRAFYMRKVKYTGEGFVEKFEDILKGFPNINDVHPFHRDLMDTLYEKNHYKISLAAISRAKSLVEQVARDYVRLLKFGQSLFQCKQLKRAALGRMATIVKKLRDPLAYLEQVRQHIGRLPSIDPNTRTLLICGYPNVGKSSFLRCITKSDVDVQPYAFTTKSLYVGHFDYKYLRFQAIDTPGILDRPTEEMNNIEMQSIYAIAHLRSCVLYFMDLSEQCGFTIEAQVKLFHSIKPLFANKSVMVVINKTDIIRPEDLDEERAQLLESVKEVPGVEIMTSSCQLEENVMEVRNKACEKLLASRIENKLKSQSRINNVLNKIHVAQPQARDDVKRTPFIPESVKN-LKKYDPEDPNRRKLARDIEAENGGAGVFNVNLKDKYLLEDDEWKNDIMPEILDGKNVYDFLDPEIAAKLQALEEEEEKLENE-GFYNSDDEEEIYDGFEASEVDDIKEKAAWIRNRQKTMIAEARNRKSLKNKAIMPRSKLTKSFG----KMEEHMSTLGHDMSALQDKQN----RAARKNRYVERGSDVVFG----DQDALTASTENGVKLRQTDRLLDGVADGSMRSKADRMAK-MERRERNRHAKQGESDRHNAVSLSKHLFSGKRGVGKTDFR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:*.* .*..*:*::*: *.:********:: ::* *** ** ****:* :.: :::.:*: .**:::*:***: ***: **:*:***::*. :. *: **::**:*****:*:*:**::*****:******.*::*: . * ********:.***:*** :**:::**:********:. :*::**:***********:*** ******:*.:*******:* *: * ****:* *:****:.***.**:*****. :. *: **..*:*** **.:::. .* :: :* *: :: .:: .. :: * * .*::*:.:**::**: *:: *:: : :::::**::*:* * *** *.* *** . : ::* :::* * *. : ::*:. : . : * :**: :*:* *::*. * **: **. :: . * .*:: * ** :: : . .. .: . :**. : . * ** **. :: : *:.: . : . . . : . * *: : : .**. * * :: . . :**:**. .***:**** **.: *", "identical_positions": 236, "similar_positions": 204, "identity": "35.6%" }, { "cls_id": "homologset.agr.SGD:S000006015", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BU14-1", "uniprot_id": "SEC62_MOUSE", "id": "Q8BU14-1", "name": "Translocation protein SEC62", "aln": "--------MAERRRHKKR-------------IQEVGEPSKEEKAVAKYLRFNCPTKSTNMMGHRVDYFIASKAVECLLDSKWAKAKKGEDALFTTRESVVDYCNRLLKKQFFHRALKVMKMKYDKDVKKEKDKGKSESGKEDDKKSKKESVKEEKTKKEKEKKKDGEKEDSKKEETPGTPKKKETKKKFKLEPHDDQVFLDGNEVFVWIYDPVHIKTFVMGLILVIAVIAATLFPLWPAEMRVGVYYLSVGAGCFVASILLLAIARCILFLIIWLITGGRHHFWFLPNLTADVGFIDSFRPLYTHEYKG----PKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKGAPADHGPEGSGGERHSDTDSDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCDE-EDDDKDGEVPKSAHEKS-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99442-1", "uniprot_id": "SEC62_HUMAN", "id": "Q99442-1", "name": "Translocation protein SEC62", "aln": "--------MAERRRHKKR-------------IQEVGEPSKEEKAVAKYLRFNCPTKSTNMMGHRVDYFIASKAVDCLLDSKWAKAKKGEEALFTTRESVVDYCNRLLKKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKKKFKLEPHDDQVFLDGNEVYVWIYDPVHFKTFVMGLILVIAVIAATLFPLWPAEMRVGVYYLSVGAGCFVASILLLAVARCILFLIIWLITGGRHHFWFLPNLTADVGFIDSFRPLYTHEYKG----PKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEKS-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VL49-1", "uniprot_id": "Q9VL49_DROME", "id": "Q9VL49-1", "name": "Translocation protein SEC62", "aln": "MSGEEEYFQEEEEEEQEQDIYDDGTEYTEPGAQKVDKPSKDEKNVAKWLKKNVKTKKTKFLSHIVEYFTSSKAIDALLKSKFTEG---SNPLFTTREQVIEFLDVMLEHKFFHRAKKVPVTLEEIRGKSGGDKKADKEKTQDKEKDKAKDEKKDTDPEGDNGQGDGGASGNEKEKE----KKEKKKRKIRLDMHPEQIFVDGSEAYVWIYDPIPLHYWIFGFILLLGAVGICLFPLWPPLLRKGVYYLSIAAAGFLVFILALTIVRLIVFIIVWALTGGKLHFWIFPNLTEDVSFFASFWPLYESNYNSDPNNSSAKTDKKSKSKDKKKEKESDAEDTAVDADGDADGDVDAEVSTLEPEKIELIKEHDTDMEIRKRRKVGADDYEEDDVDEEETKAQPKDSKAGTPRNSGSDSESSSKDYEIISSSEVQNVAGN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21825-1", "uniprot_id": "SEC62_YEAST", "id": "P21825-1", "name": "Translocation protein SEC62", "aln": "--------MSAVGPGSNAG-------------ASVNGGSATAIATLLRNHKELKQRQGLFQAKQTDFFRYKRFVRALHSEEYANKSARQPEIYPT-IPSNKIEDQLKSREIFIQLIKAQMVIPVKKLHSQECKEHG----------------------------------------------LKPSKDFPHLIVSNKAQLEADEYFVWNYNPRTYMDYLIVIGVVSIILALVCYPLWPRSMRRGSYYVSLGAFGILAGFFAVAILRLILYVLSLIVYKDVGGFWIFPNLFEDCGVLESFKPLYGFGEKD-----TYSYKKKLKRMKKKQAKRESNKKKAINEKAEQN----------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .*. * . : : :. : .: .::* .: : .* ..:::: . ::.* . : : .:::* : *. :. * : .:.: :: ::..* :** *:* ::: : :: :. :**** :* * **:*:.* ::. :: ::: * *:::: : . **::*** * ..: ** *** :. . . .*. * **: * .. :.. : . : : ", "identical_positions": 41, "similar_positions": 101, "identity": "9.43%" }, { "cls_id": "homologset.agr.SGD:S000006016", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A3D4-1", "uniprot_id": "D4A3D4_RAT", "id": "D4A3D4-1", "name": "Phospholipase ABHD3", "aln": "MGQRILSLYPASSPSPSALESEASAGLLQTAASSWAESTGSRSSGGPACFHLGSRALSWLWRDTGGPQSGGVPARVWKVRRWGGAGRAWSRLQGRGWLRPSRAPPLRRLFPASPVPRAPASWPPLQLRRARAMQRLAMDLRVLSRELALYVEH------QVRVGFFGSGVGLSLILG--------FSVAYACYYLSSIAKKPQLVIGGESFSRFLQDHCPVVTETYYP-TVWCWESRGQTLLRPFITAK--PRVQYRNELIKTADGGQ--ISLDWFDNNNSAC--YVDASTRPTILLLPGLTGTSKESYILHMIHLSEELG---YRCVVFNNRGVA-GESLLTPRTYCCANTEDLEAVIHHVHSLYPL-APFLAAGVSMGGMLLLNYLGKIGSKTP--LMAAATFSVGWNTFACSES-LERPLNWLLFNYYLTTCLQSSVKKHRHMFVGQ---------------------IDMDQVMKAKSIREFDRRFTSVMFGYRT-LDDYYTDASPNRRLKSVGIPVLCLNAADDVFSPSHAIPIETAK--QNPNVALVLTSYGGHIGFLEG--IWP-RQCTYMD--RVFKQ-FVQAMVEHGHELSNM----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZH7-1", "uniprot_id": "ABHD3_MOUSE", "id": "Q91ZH7-1", "name": "Phospholipase ABHD3", "aln": "------------------------------------------------------------------------------------------------------------------------------------MQRLAMDLRVLSRELALYLEH------QVRVGFFGSGVGLSLILG--------FSVAYACYYLSSIAKKPQLVIGGESFSRFLQDHCPVVTETYYP-TVWCWESRGQTLLRPFITSK--PPVQYRNELIKTADGGQ--ISLDWFDNNNSAY--YVDASTRPTILLLPGLTGTSKESYILHMIHLSEELG---YRCVVFNNRGVA-GESLLTPRTYCCANTEDLEAVVHHVHSLYPG-APFLAAGVSMGGMLLLNYLGKIGSKTP--LMAAATFSVGWNTFACSES-LERPLNWLLFNYYLTTCLQSSVKKHRHMFVEQ---------------------IDMDQVMKAKSIREFDKRFTAVMFGYRT-LDDYYTDASPNRRLKSVGIPVLCLNATDDVFSPSHAIPIETAK--QNPNVALVLTAYGGHIGFLEG--IWP-RQCTYMD--RVFKQ-FVQAMVEHGHELSNM----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WU67-1", "uniprot_id": "ABHD3_HUMAN", "id": "Q8WU67-1", "name": "Phospholipase ABHD3", "aln": "------------------------------------------------------------------------------------------------------------------------------------MQRLAMDLRMLSRELSLYLEH------QVRVGFFGSGVGLSLILG--------FSVAYAFYYLSSIAKKPQLVTGGESFSRFLQDHCPVVTETYYP-TVWCWEGRGQTLLRPFITSK--PPVQYRNELIKTADGGQ--ISLDWFDNDNSTC--YMDASTRPTILLLPGLTGTSKESYILHMIHLSEELG---YRCVVFNNRGVA-GENLLTPRTYCCANTEDLETVIHHVHSLYPS-APFLAAGVSMGGMLLLNYLGKIGSKTP--LMAAATFSVGWNTFACSES-LEKPLNWLLFNYYLTTCLQSSVNKHRHMFVKQ---------------------VDMDHVMKAKSIREFDKRFTSVMFGYQT-IDDYYTDASPSPRLKSVGIPVLCLNSVDDVFSPSHAIPIETAK--QNPNVALVLTSYGGHIGFLEG--IWP-RQSTYMD--RVFKQ-FVQAMVEHGHELS------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QZC8-1", "uniprot_id": "ABHD1_MOUSE", "id": "Q9QZC8-1", "name": "Protein ABHD1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MEYPYTTKMLSSSLSP------QN--GTWSDTISLLLALG--------VAL-YLGYYWACVPQRPRLVAG-PQFLAFLEQHCPVTVETFYP-TLWCFEGRLQTIFRVLLQSQ--PVVPYRSEVLQTPDGGQ--FLLDWAEQPNSTH--YPDPTTQPIVLLLPGISGSSQEPYILHLVNQALKDG---YRAVVFNNRGCR-GEELLTHRAYCASNTEDLETVVKHIKRRYSQ-APLLAVGISFGGILVLNYLAQTGKAGG--LVAGLTMSACWDSFETVDS-LETPLNSLLFNQPLTAGLCRLVARNRKPIEKV---------------------LDVDFAIKARTIRQLDERYTSVAFGYKD-CAAYYQAASPRTKVDAIHTPVLCLNAADDPFSPVHAFPLQAAQ--KSPYVALLITARGGHIGFLEG--LMP-WQHCYMN--RVLHQ-YARAIFQHSVGLPDLG--------VLTP-EDGKS---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5RK23-1", "uniprot_id": "ABHD1_RAT", "id": "Q5RK23-1", "name": "Protein ABHD1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MEYLHITKMLSSSLSP------QN--GTWSDAISLLLALG--------IAL-YLGYYWACVPQRPRLVAG-PQFLAFLEQHCPVTVETFYP-TLWCFEGRLQTIFRVLLQSQ--PVIPYRSEVLQTPDGGQ--FLLDWAEQPYSSH--CPDPTTQPIVLLLPGISGSSQEPYILHLVDQALKDG---YRAVVFNNRGCR-GEELLTHRAYCASNTEDLETVVKHIKHRYSR-APLLAVGISFGGILVLNYLARTGKAGG--LVAGLTMSACWDSFETVDS-LETPLNSLLFNQPLTAGLCRLVARNRKSIEKV---------------------LDVDFAIKARTIRQLDERYTSVAFGYKD-CAAYYHASSPRTKVDAICTPVLCLNAADDPFSPVQALPLQAAQ--KSPYVALLITARGGHIGFLEG--LLP-WQHCYMN--RVLHQ-YARAVFQHSVGLPGLG--------ALTP-EDGKS---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96SE0-1", "uniprot_id": "ABHD1_HUMAN", "id": "Q96SE0-1", "name": "Protein ABHD1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MLSSFLSP------QN--GTWADTFSLLLALA--------VAL-YLGYYWACVLQRPRLVAG-PQFLAFLEPHCSITTETFYP-TLWCFEGRLQSIFQVLLQSQ--PLVLYQSDILQTPDGGQ--LLLDWAKQPDSSQ--DPDPTTQPIVLLLPGITGSSQETYVLHLVNQALRDG---YQAVVFNNRGCR-GEELRTHRAFCASNTEDLETVVNHIKHRYPQ-APLLAVGISFGGILVLNHLAQARQAAG--LVAALTLSACWDSFETTRS-LETPLNSLLFNQPLTAGLCQLVERNRKVIEKV---------------------VDIDFVLQARTIRQFDERYTSVAFGYQD-CVTYYKAASPRTKIDAIRIPVLYLSAADDPFSPVCALPIQAAQ--HSPYVALLITARGGHIGFLEG--LLP-WQHWYMS--RLLHQ-YAKAIFQDPEGLPDLR--------ALLPSEDRNS---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z7Q7-1", "uniprot_id": "A1Z7Q7_DROME", "id": "A1Z7Q7-1", "name": "", "aln": "----------------------------------------------------------MLCALVRGPTTGHKLVLYRSVAELLGPVHDIRCLSAGRGVYQRQS-------------RSQSQSQSQLQNPAHRPDLLSLSRPALSSKLSVRSLH------SENDAMFYSMYAYLSNLPR-LHVLGMAVVAYVVYYLIQVVKRPIIACSDGPFKQYLIRKVPTLENKYWP-TFWCVESRAQTVLASLLRSKSLPRVNYRREILSLKDGGE--VALDWMEEG--------CDQSAPCILILPGLTGESQAEYIKCLVFAAQQAG---MRVVVFNNRGLG-GIELKTPRLYCAANCEDLCEVVQHVRRTLPEKCKLGATGISMGGLILGNYLARKSDEARSFLSAAKIISVPWDVHKGSAS-IEKPVINSLLGRHLAGSLCRTLRNHLDIYRDIY-----------QD-----SDIDIQRILRCKTIKEFDALFTAKQFGYAH-VNDYYSDATLHNKLDHISVPLLCLSAADDPFQPLDAIPIKAAN--QCTHVAIVITARGGHIGFLEG--WWPSTKDQYMG--RLFTEYFTKALFDEDGEFQHTANKMHERFLAKQTVALASSSPVLFAKKIDADQLDHKVKLM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9QXM0-1", "uniprot_id": "ABHD2_MOUSE", "id": "Q9QXM0-1", "name": "Monoacylglycerol lipase ABHD2", "aln": "------------------------------------------------------------------------------------------------------------------------------------MN-----AMLETPELPAVFDG------VKLAAVAAVLYVIVRCLN-----------------LKSPTAPPDLYFQDSGLSRFLLKSCPLLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITMSDGAT--STFDLFEPLAEHC--VGDDIT---MVICPGIANHSEKQYIRTFVDYAQKNG---YRCAVLNHLGALPNIELTSPRMFTYGCTWEFGAMVNYIKRTYPQ-TQLVVVGFSLGGNIVCKYLGETQ-ANQEKVLCCVSVCQGYSALRAQETFMQWDQCRRFYNFLMADNMKKIILSHRQALFGDH-----------VKKPQSLEDTDLSRLYTATSLMQIDDNVMRKFHGYNS-LKEYYEEESCMRYLHRIYVPLMLVNAADDPLVHESLLTIPKSLSEKRENVMFVLPLHGGHLGFFEGSVLFP-EPLTWMD--KLVVE-YANAICQWERNKSQCSDTEQMEAELE-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A7W1-1", "uniprot_id": "D4A7W1_RAT", "id": "D4A7W1-1", "name": "Monoacylglycerol lipase ABHD2", "aln": "------------------------------------------------------------------------------------------------------------------------------------MN-----AMLETPELPAVFDG------VKLAAVAAVLYVIVRCLN-----------------LKSPTAPPDLYFQDSGLSRFLLKSCPLLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITMSDGAT--STFDLFEPLAEHC--VGDDVT---MVICPGIANHSEKQYIRTFVDYAQKNG---YRCAVLNHLGALPNIELTSPRMFTYGCTWEFGAMVNYIKKTYPQ-TQLVVVGFSLGGNIVCKYLGETQ-ANQEKVLCCVSVCQGYSALRAQETFMQWDQCRRFYNFLMADNMKKIILSHRQALFGDH-----------VKKPQSLEDTDLSRLYTATSLMQIDDNVMRKFHGYNS-LKEYYEEESCMRYLHRIYVPLMLVNAADDPLVHESLLTIPKSLSEKRENVMFVLPLHGGHLGFFEGSVLFP-EPLTWMD--KLVVE-YANAICQWERNKSQCSDTEQMEAELE-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08910-1", "uniprot_id": "ABHD2_HUMAN", "id": "P08910-1", "name": "Monoacylglycerol lipase ABHD2", "aln": "------------------------------------------------------------------------------------------------------------------------------------MN-----AMLETPELPAVFDG------VKLAAVAAVLYVIVRCLN-----------------LKSPTAPPDLYFQDSGLSRFLLKSCPLLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITMSDGAT--STFDLFEPLAEHC--VGDDIT---MVICPGIANHSEKQYIRTFVDYAQKNG---YRCAVLNHLGALPNIELTSPRMFTYGCTWEFGAMVNYIKKTYPL-TQLVVVGFSLGGNIVCKYLGETQ-ANQEKVLCCVSVCQGYSALRAQETFMQWDQCRRFYNFLMADNMKKIILSHRQALFGDH-----------VKKPQSLEDTDLSRLYTATSLMQIDDNVMRKFHGYNS-LKEYYEEESCMRYLHRIYVPLMLVNAADDPLVHESLLTIPKSLSEKRENVMFVLPLHGGHLGFFEGSVLFP-EPLTWMD--KLVVE-YANAICQWERNKLQCSDTEQVEADLE-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q802V6-1", "uniprot_id": "ABH2A_DANRE", "id": "Q802V6-1", "name": "Monoacylglycerol lipase ABHD2", "aln": "------------------------------------------------------------------------------------------------------------------------------------MNTHESEVYTVAPEMPAMFDG------MKLAAVATVLYVIVRCLN-----------------LKSPTAPPDLTFQDTTLNHFLLKSCPILTKEYIPPLLWGKSGHLQTALYGKLGRVSSPHPFGLRKYLPMQDGAT--ATFDLFEPLADHQ--SGEDVT---MVICPGIGNHSEKHYIRTFVDHSQKQG---YRCAVLNHLGALPNIELTSPRMFTYGCTWEFAAMVGFIKKTYPQ-SKLIVVGFSLGGNIVCKFLGENR-TNQERVLCCVSVCQGYSALRAQETFLQWDQCRRFYNFLMADNMKKIILSHRGVLFGVG-----------SK----MVDSELSRLYTATSLMQIDDNIMRKFHGHNS-LKEYYEKESCVHYIHNINVPLLLVNSVDDPLVHNSLLTIPRTLAEKKENVVFALTLHGGHLGFFEGAVLFP-QPLTWMD--KVIVD-YATAMCQWEKQKPPCQSKDAQSNQTTCQENTS-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24093-1", "uniprot_id": "ABHD2_DROME", "id": "Q24093-1", "name": "Abhydrolase domain-containing protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MSTAF----------LTLIAVIVCILFRILN-----------------VHSQPLKPSVWCLDAHFLDCLYKIAPVLREPYIPPRLWGFSGHVQTVLHSIVGRVRCPWPLGERVYMSLKDGST--LTYDLYQPLNEQ----EDDIT---VAICPGIANSSESVYIRTFVHLAQCNG---YRCAVLNHIGALRSVQVTSTRIFTYGHTEDFAAMVEHLHQKYRQ-SRIVAVGFSLGGNLVTKYMGEDQKTKPDKVIGGISICQGYNAVEGTKWLLNWQNFRRFYLYIMTENVKSIILRHRHILLSDE-----------VKARHNLNERE---IIAAATLPELDEAYTRRVYNFPS-TQELYKWSSSLFYFDTIKKPMIFINAKDDPLIPEDLLHPIKEYATTRQNTAYVEVAHGGHLGFYEGGFLYP-NPVTWLD--RTLVA-MVGSLVMMHEVGKVAP---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q5F2F2-1", "uniprot_id": "ABH15_MOUSE", "id": "Q5F2F2-1", "name": "Protein ABHD15", "aln": "------------------------------------------------------------------------------------------------------------------------------------MPPWAAALALLLAALALLLLR------PWKRAVGARTS--VRDHEE-QEVASGGPADQFSDRREALPGGCSLICKPSALAQCLLRALRRSAALEPSPRSWLSGPHLQTFCHFILPVG--PGPELAREYLQLADDGL--VALDWVIGPCARGRRVTNPGSLPPVLLVIPNAWGRLTRNVLGLCLLALERG---YYPVIFHRRGHH-GCPLVSPRLQPFGDPSDLKEAVTYIRFRHPA-APLFAVSEGSGSALLLSYLGECGSSSY--VTGAACISPVLRCREWFEAGLPWPYERGFLLHQKIS-----LSRYASALEDT---------------------VDTGKLFRSGSLREFEETLFCHTKSCPISWDTYWDLNDPLRDVDEAAVPVLCICSADDPVCGPPEHTLPAELFHSNPYFFLLLSHHGGHCGFLRPEPLPAWSHEVILESFRALTEFFRMEERMKGLSRRRTSFLGGRRRWGGLQKREVSPSSNLEEIFNWKRSYTR-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z8B6-1", "uniprot_id": "D3Z8B6_RAT", "id": "D3Z8B6-1", "name": "Protein ABHD15", "aln": "------------------------------------------------------------------------------------------------------------------------------------MPPWPAALALLLAALALLLLR------PWKRAVGARTS--VRDHEE-QEVVSGGPADHFSDRREPLPGGCSLICKPSALAQCLLRALRRSAALEPSPRSWLSGPHLQTFCHFILPVG--PDPELAREYLQLADDGL--VALDWVIGPCARGRRVTNPGSLPPVLLVIPNAWGRLTRNVLGLCLLALEHG---YYPVIFHRRGHH-GCPLVSPRLQPFGDPSDLKEAVTYIRFRHPA-APLFAVSEGSGSALLLSYLGECGSSSY--VTGAACISPVLRCREWFEAGLPWPYERGFLLYQKIA-----LSRYASALEDT---------------------VDTGKLFKSSSLREFEETLFCHTKSLPISWDTYWDLNDPLRDVDEAAVPVLCICSADDPVCGPPDRTLPAELFHTNPYFFLLLSSHGGHCGFLRPEPLPAWSHEIILESFRALTEFFRMEERMKGLSRRRTSFLGGRRRWGGLQKREVSPSSNLEEIFDWKRSYTR-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UXT9-1", "uniprot_id": "ABH15_HUMAN", "id": "Q6UXT9-1", "name": "Protein ABHD15", "aln": "------------------------------------------------------------------------------------------------------------------------------------MPPWGAALALILAVLALLGLLGPRLRGPWGRAVGERTLPGAQDRDDGEEADGGGPADQFSDGREPLPGGCSLVCKPSALAQCLLRALRRSEALEAGPRSWFSGPHLQTLCHFVLPVA--PGPELAREYLQLADDGL--VALDWVVGPCVRGRRITSAGGLPAVLLVIPNAWGRLTRNVLGLCLLALERG---YYPVIFHRRGHH-GCPLVSPRLQPFGDPSDLKEAVTYIRFRHPA-APLFAVSEGSGSALLLSYLGECGSSSY--VTGAACISPVLRCREWFEAGLPWPYERGFLLHQKIA-----LSRYATALEDT---------------------VDTSRLFRSRSLREFEEALFCHTKSFPISWDTYWDRNDPLRDVDEAAVPVLCICSADDPVCGPPDHTLTTELFHSNPYFFLLLSRHGGHCGFLRQEPLPAWSHEVILESFRALTEFFRTEERIKGLSRHRASFLGGRRRGGALQRREVSSSSNLEEIFNWKRSYTR-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02891-1", "uniprot_id": "MCFS1_YEAST", "id": "Q02891-1", "name": "Medium-chain fatty acid ethyl ester synthase/esterase 1", "aln": "--------------------------------------------------------------------------------------------------------------------MFRSGYYPTVTPSHWGYNGTVKHVLGEKGTKSLAFRDS-----KRQIPLHEFVTKHVPTLKDG----ANFRLNSLLFTGYLQTLYLSAGDFSKKFQVFYGREIIKFSDGGVCTADWVMPEWEQTYSLNAEKASFNEKQFSNDEKATHPKGWPRLHPRTRYLSSEELEKCHSKGYSYPLVVVLHGLAGGSHEPLIRALSEDLSKVGDGKFQVVVLNARGCS-RSKVTTRRIFTALHTGDVREFLNHQKALFPQ-RKIYAVGTSFGAAMLTNYLGEEGDNCP--LNAAVALSNPWDFVHTWDKLAHDWWSNHIFSRTLTQFLTRTVKVNMNELQVPENFEVSHKPTVEKPVFYTYTRENLEKAEKFTDILEFDNLFTAPSMGLPD-GLTYYRKASSINRLPNIKIPTLIINATDDPVTGENVIPYKQAR--ENPCVLLCETDLGGHLAYLDN------ESNSWLT---KQAAEFLGSFDELVL---------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * *: .. : : : : * .::: * : : * :. : . : : ... . *. :: ..:.. : .. : : : : ::: . : . * : : : ** . *** .: : ", "identical_positions": 12, "similar_positions": 53, "identity": "1.87%" }, { "cls_id": "homologset.agr.SGD:S000006017", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI55-1", "uniprot_id": "NGLY1_RAT", "id": "Q5XI55-1", "name": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase", "aln": "----MASATLGSSSSSASPAVAELCQNTPETFLEASKLLLTYADNILRNPSDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEG--ETHLIFPKKASVEQLQKIRDLIAVERRSRLDGS--SQKVEFSQHPAA-VRLPAEQPEDPTGLMQHSGNQPGQPLSLPSAPLVVGDSTIFKVLQSNIQHVQLYENPVLQEKALACIPVNELKRKSQEKLFRARKLDKGTKVSDE-----DFLLLELLHWFKEEFFHWVNNVVCSRCGR---ETRSRDEALPPNDDELKWGAKNVEDHYCDACQLSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRALGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYIIAFSKDEVVDVTWRYSCKHEEVMSRRTKVKEELLRETINGLNKQRQLLLSESRRKELLQRIIVELVEFISPKTPRPGELGGRVSGSLAWRVARGETCLE-----RKEILFIPSENEKISKQFHLRYDIVRDRYIRVSDNN------ANISGWENGVWKMESIFRKVEKDWNMVYLARKEGSSFAYISWKFECGSAGLKVDNVSIRTSSQSFETGSVRWKLRSEMAQVNLLGDRNLRSYDDFCGATEVTLEAELSRGDGDVAWQHTQLFRQSLNDHAENGLEIIITFSDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JI78-1", "uniprot_id": "NGLY1_MOUSE", "id": "Q9JI78-1", "name": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase", "aln": "----MASATLGSSSSSASPAVAELCQNTPETFLEASKLLLTYADNILRNPSDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEG--ETHLIFPKKASVEQLQKIRDLIAIERSSRLDGS--SKKVQFSQHPAA-AKLPLEQSEDPAGLIRHSGNQTGQLPSLPSAPMVVGDSTILKVLQSNIQHVQLYENPVLQEKALTCIPVSELKRKAQEKLFRARKLDKGTNVSDE-----DFLLLELLHWFKEEFFRWVNNIVCSKCGG---ETRSRDEALLPNDDELKWGAKNVENHYCDACQLSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRALGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYIIAFSKDEVVDVTWRYSCKHDEVMSRRTKVKEELLRETINGLNKQRQLSLSESRRKELLQRIIVELVEFISPKTPRPGELGGRVSGSLAWRVARGETGLE-----RKEILFIPSENEKISKQFHLRYDIVRDRYIRVSDNN------INISGWENGVWKMESIFRKVEKDWNMVYLARKEGSSFAYISWKFECGSAGLKVDTVSIRTSSQSFESGSVRWKLRSETAQVNLLGDKNLRSYNDFSGATEVTLEAELSRGDGDVAWQHTQLFRQSLNDSGENGLEIIITFNDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96IV0-1", "uniprot_id": "NGLY1_HUMAN", "id": "Q96IV0-1", "name": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase", "aln": "----MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEG--ETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDE-----DFLLLELLHWFKEEFFHWVNNVLCSKCGG---QTRSRDRSLLPSDDELKWGAKEVEDHYCDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARRTKVKEALLRDTINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQ-----RKETLFIPCENEKISKQLHLCYNIVKDRYVRVSNNN------QTISGWENGVWKMESIFRKVETDWHMVYLARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTVEWKLRSDTAQVELTGDNSLHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEENCLEIIIKFSDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q503I8-1", "uniprot_id": "NGLY1_DANRE", "id": "Q503I8-1", "name": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase", "aln": "--------------MPGSQGVLALCENTTEVFLDVSKLLITYADNILRNPNEEKYRSIRIGNPTFSTKLLPVKGAVECLFEMGFEEA--ETHLVFPRSASVEKLRQVRETIAAERDQRLGAS----NTASSPQNASVPPVPAPPPSLSSTASAGPAAAAVPTPAPASIPFTSSSATFQRTVQSNFQHVLVYEDPELQQKALECIPHELLRSRAKERLKQANDADAACSLGEE-----DMLVLDLLQWFKSDFFSWVDNLPCIQCGG---KTQPSG-SLSPSSDDLHWDAGRVENHFCHTCQLSTRFPRYNNPEKLLETRKGRCGEWANCFTLLCRALGLEARYIWDSTDHVWTEVYSQSQRRWIHCDPCENACDKPLLYEVGWGKKLSYILAFSKDQVADVTWRYSCKHPEVLSRRTQVQETWLLHMLNKLNAERQQFLGAERKQQLLQRLLVELVEFISPKSPQPGELGGRMSGSLAWRAARGETGASNAKEDTQENVFTPSESEKESKRFHICYNVTKDCYYRVSNGQ------ETIQGWQKGAWRTENMFRKEEHDWQMVYLARTEGASFGRMSWKFNCAPAGMKMKSASVRVFSQTFHSGTVRWSLSTNETTTEFPGDGELHSFSNVSGGTELIVEAELTGGDGSTSWQHAQLFRQSLKDTEKVLFEVMVEMEKS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KRR5-1", "uniprot_id": "NGLY1_DROME", "id": "Q7KRR5-1", "name": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase", "aln": "MVDINLECVHQIEPKTRSAGQQQQERGLKEAYLEAVRILLVLLENILAQPENSMFRTIRQENKAIKEKLLSLPGCERLLEAIGFVRAPSSNAYTLPTEVSLQQVKKYRDALSERRTAWLNGT---------------VSKSPPQQSTTSTTPLFIKPSVEYRHRIAFPRVLRTNNNFLQSLELYSDAVMQYEDNLLLATGRTLIPVEELTEMASEKLIDIQDQIASGERQEKEPCVRDLLLVELVNWFNTQFFQWVNNIPCRVCGS---EESRLRRTEREGD---------IRVEVTVCCGQESKFYRYNDISQLLVSRKGRCGEYANCFTFLCRALDYDARIVHSHFDHVWTEVYSEAQMRWLHVDPSENVIDSPLMYQHGWKRHIDYILAYSRDDIQDVTWRYTNDHQKILHLRKLCGEKEMVQTLDAIRAKRRQNCTADRKLFLSQRNMYEVIGLTLERKPTENELKGRSSGSLSWRQSRGEHTFT------NIFVFNLSATELQKRQLNVRYSCATDTYERYAKEGEHITILDSYKTWQKAQFSSKNIFRKVERDWKMAYLARLEDTDCGEIAWTFDFSKTNLKVKSYNLVFETKTFGDGKISVTVDATDGSASVEN------------ATGFKIVAKLTGGKGDVAWQHTQLFRQSLN-SRDYPFDLQVQLH--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02890-1", "uniprot_id": "PNG1_YEAST", "id": "Q02890-1", "name": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase", "aln": "--------------------MGEVYEKNNIDFDSIAKMLLIKYKDFILS--------------------------------------------KFKKAAPVENIR-------------------------------------------------------------FQNLVHTNQFAQGVLGQSQHLCTVYDNPSWHSIVLETLDLDLIYKNVDKEFAKDGHAEGENIYTDY-------LVKELLRYFKQDFFKWCNKPDCNHCGQNTSENMTPLGSQGPNGEESKFNCGTVEIYKCNRCGNITRFPRYNDPIKLLETRKGRCGEWCNLFTLILKSFGLDVRYVWNREDHVWCEYFSNFLNRWVHVDSCEQSFDQPYIYSINWNKKMSYCIAFGKDGVVDVSKRYILQN---ELPRDQIKEEDLKFLCQFITKRLRYSLNDDEIYQLACRDEQEQIELIRGKTQETKSESVSAASKSSNR-----------------------------------------------------------------------------------------GRESGSADWKAQRGEDGK--------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . ::*: .::: . : ..::::: . : . *:: : . : .:.: . : *: :*:.:*: :** * :: * ** : : .. :. * .:* ***: :** :* *****:.* **: ::.. :.* : . **** * :* **:* *..*: *.* :*. .* :::.* :*:.:* : **: ** .: * * : : : . : .. * * * : : :. . :.. : * . . . *. : . . ", "identical_positions": 57, "similar_positions": 108, "identity": "8.39%" }, { "cls_id": "homologset.agr.SGD:S000006018", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5I0L3-1", "uniprot_id": "SYYM_RAT", "id": "Q5I0L3-1", "name": "Tyrosine--tRNA ligase, mitochondrial", "aln": "-----MAAPMLRHLCR------VPQSGVWTRGPRAVRPGARGMLVAPRARGLFKEFFPESG------TKTELPELFDRRRAGS-PQTVYCGFDPTGDSLHVGHLLTLLGLFHFQRAGHNVIALVGGSTALLGDPSGRTKEREALSAECVRANARALQRGLETLAANHARLFADGR------PWGTFTVLDNAAWFQKQHLMDFLATVGGHFRMGTLLSRLSVQSRLKSPEGMSLAEFFYQVLQAYDFYYLFRHYGCRVQLGGSDQLGNIMSGYEFIHKLTG----EDVFGITVPLITSTTGAKLGKSAGNAVWLNREKTSPFELYQFFIRQQDDSVERYLKLFTFLPLPEIDHIMQLHVKEPEKRIAQKRLAAEVTKLVHGQEGLDSAKRCTQALYHSSIEALEVMSDQELKELFKEASFSELVLDPGTSVIDTCRKANAIPDGPRGYRMITEGGVSINHRQVTNPESVLVIGQHILKNGLSLLKIGKRNFYIIKWLQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BYL4-1", "uniprot_id": "SYYM_MOUSE", "id": "Q8BYL4-1", "name": "Tyrosine--tRNA ligase, mitochondrial", "aln": "-----MAAPMLRRLCR------VPQSLVWLRGSRAVRPGARGMLVAPRARGLFKEFFPESG------TKTELPELFDRRRAGSSPQTVYCGFDPTGDSLHVGHLLTLLGLFHFQRAGHNVIALVGGSTALLGDPSGRTKGREALSAECVRANAHALRRGLEALAANHARLFADGR------PWGSFTVLDNAAWFQEQHLVDFLATVGGHFRMGTLLSRLSVQSRLKSPEGMSLAEFFYQVLQAYDFYYLFQHYGCRVQLGGSDQLGNIMSGYEFIHKLTG----EDVFGITVPLITSTTGAKLGKSAGNAVWLNREKTSPFELYQFFVRQQDDSVERYLKLFTFLPLPEIDHIMQLHVKEPEKRVAQKRLAAEVTKLVHGQEGLDSAKRCTQALYHSSIEALEVMSDQELKELFKEASFSELVLDPGTSVIDTCRKANAIPDGPRGYRMITEGGVSINHRQVTNPESVLVIGQHILKNGLSLLKIGKRNFYIIKWLQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2Z4-1", "uniprot_id": "SYYM_HUMAN", "id": "Q9Y2Z4-1", "name": "Tyrosine--tRNA ligase, mitochondrial", "aln": "-----MAAPILRSFSWGRWSGTLNLSVLLPLGLRKAHSGAQGLLAAQKARGLFKDFFPETG------TKIELPELFDRG-TASFPQTIYCGFDPTADSLHVGHLLALLGLFHLQRAGHNVIALVGGATARLGDPSGRTKEREALETERVRANARALRLGLEALAANHQQLFTDGR------SWGSFTVLDNSAWYQKQHLVDFLAAVGGHFRMGTLLSRQSVQLRLKSPEGMSLAEFFYQVLQAYDFYYLFQRYGCRVQLGGSDQLGNIMSGYEFINKLTG----EDVFGITVPLITSTTGAKLGKSAGNAVWLNRDKTSPFELYQFFVRQPDDSVERYLKLFTFLPLPEIDHIMQLHVKEPERRGPQKRLAAEVTKLVHGREGLDSAKRCTQALYHSSIDALEVMSDQELKELFKEAPFSEFFLDPGTSVLDTCRKANAIPDGPRGYRMITEGGVSINHQQVTNPESVLIVGQHILKNGLSLLKIGKRNFYIIKWLQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W107-1", "uniprot_id": "SYYM_DROME", "id": "Q9W107-1", "name": "Tyrosine--tRNA ligase, mitochondrial", "aln": "------MLPLRRSLLK-------PLQDVLRHSHRQMS---QKNLLELTDRGFFHGIFPDT-------AAPRMKQLFTRG-----QQSIYAGFDPTADSLHVGNLLVIMGLIHCQRAGHRPIALVGGATGLIGDPSGRKTERNQLGETVIETNLKAIEQQLRRVFENHENCLWDSKKQ--KLPLAPLIIVNNADWYADLQLIDFVANMGRHFRMGSMLSRSSVQSRLESEDGMSFTEFTYQIFQAYDWLHLLRRHNCCFQMGGSDQTGNLMTGHELISRVERK---REVFGLTLPLVTTEEGDKFGKSAGNAVWLDGNKTSPFALYQFFLRMPDSEVEKLLKLFTFIPLPQVEQLMREHTKEPEKRKAQTLLAEDVTLLVHGESGLKQAERVTNALYKGNVEGLAELNLSEIQQTFQGATMVNLLTEPGMSILELAMKAKCFPTETDAVRIINAGGFYVNQKRVQNIAEVLTTGVHILRNGISLLRVGKRNFYIVRWQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48527-1", "uniprot_id": "SYYM_YEAST", "id": "P48527-1", "name": "Tyrosine--tRNA ligase, mitochondrial", "aln": "MLELRSCSNLVNSSRRLVPLVTYSGLSAITLPKSRFYSQPSALEVQGTSDSRSDNILDELKQRGLVSQVSQPESFLRTKLNGNDKIKLYCGVDPTAQSLHLGNLVPLMVLLHFYVKGHDIVTVIGGATGKVGDPSGRKTERDVMENDIRQSNVASISQQLQRFFKNGLEYYRNRCALTEDVPSGKYTPRNNFNWWKDIKMLDFLADFGRHIRVQSMLARDSISSRLQTKNGLGFNEFTYQVLQAYDFYHLYKEENVTIQVGGNDQWGNITAGIDLINRIQPIKNKGLPFGITVPLLTTATGEKFGKSAGNAVFIDPSINTAYDVYQFFYNTLDADVPKFLKIFTFLNSSEIKKIVETHIKSPSLRYGQTLLAKEVTDMLYGVGSGSDSEALSNIIFG---RYDGTLSAAKLVDLCKKARILQYADREIDLIKLICKLVNCSVSEAR--RKLSQGSVYLHHSKSKVNENISNLAPFLIDDRVLILRIGKQKCFIIEMR--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . :: : . .:: .:*.*.***.:***:*:*: :: *:* ** ::::**:*. :******.. *: : .:* :: *. . * . : . . :* *: . :::**:* .* *:*: ::*:* *:. **:: :*:.: ** **::****: :* :. . .*:**.** **: :* ::* :: **:*:**:*: * *:********::: . .:.: :**** . * .* : **:***: .::.:::. * *.*. * *. ** :** :::* . ..:: :: :: :. :: : : * : : : . .:. . * :. *.. ::: : .: . .:: : : :*::**:: :*:. ", "identical_positions": 103, "similar_positions": 162, "identity": "20.64%" }, { "cls_id": "homologset.agr.SGD:S000006019", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60602-1", "uniprot_id": "ROMO1_HUMAN", "id": "P60602-1", "name": "Reactive oxygen species modulator 1", "aln": "MPVAVGPYGQ-SQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIGMRGRELMGGIGKTMMQSGGTFGTFMAIGMGIRC----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60603-1", "uniprot_id": "ROMO1_MOUSE", "id": "P60603-1", "name": "Reactive oxygen species modulator 1", "aln": "MPVAVGPYGQ-SQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIGMRGRELMGGIGKTMMQSGGTFGTFMAIGMGIRC----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A742-1", "uniprot_id": "D4A742_RAT", "id": "D4A742-1", "name": "Reactive oxygen species modulator 1", "aln": "MPVAVGPYGQ-SQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIGMRGRELMGGIGKTMMQSGGTFGTFMAIGMGIRC----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NYD1-1", "uniprot_id": "ROMO1_DANRE", "id": "Q6NYD1-1", "name": "Reactive oxygen species modulator 1", "aln": "MPVSVGSYGQQAQPSCFDRVKMGFMMGFAVGMAAGAMFGTFSCLRIGMRGRELMGGVGKTMMQSGGTFGTFMAIGMGIRC----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUM2-1", "uniprot_id": "Q9VUM2_DROME", "id": "Q9VUM2-1", "name": "Reactive oxygen species modulator 1", "aln": "MPLPTSSFSQ-QGPTCFDKMKTGFIIGFCVGMASGAVFGGFSALRYGLRGRELINNVGKTMVQGGGTFGTFMAIGTGIRC----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02889-1", "uniprot_id": "MGR2_YEAST", "id": "Q02889-1", "name": "Protein MGR2", "aln": "MPPLPQNYAQ-QQPSNWDKFKMGLMMGTTVGVCTGILFGGFAIATQGPGPDGVVRTLGKYIAGSAGTFGLFMSIGSIIRSDSESSPMSHPNLNLQQQARLEMWKLRAKYGIRKD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :.* *: :*:.* *:::* **:.:* :** *: * :: :** : ..**** **:** **. ", "identical_positions": 27, "similar_positions": 22, "identity": "23.68%" }, { "cls_id": "homologset.agr.SGD:S000006021", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80W47-1", "uniprot_id": "WIPI2_MOUSE", "id": "Q80W47-1", "name": "WD repeat domain phosphoinositide-interacting protein 2", "aln": "-------MNLAS-QSGEAG--AGQLLFANFNQDNT------------------SLAVGSKSGYKFFSLSSVD-----------KLEQIYECTDTEDVCIVERLFSSSLVAIVS----LKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEES-LYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSASIGEVQVFDTINLRAANMIPAHDSPLAALAFDAS---GTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASS-NTETVHIFKLEA-VREK-----PPEEPTTWTGY--FGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLTTIQKIPRLLVGA--SDGYLYMYNLDPQEGGECALMRQHRLDGSMETTSEIVDSASHDCPLATQTYGTAAAKGAYVPSSPTRLGKGQDANLEAYTD--------------DLGAVGGACLEDEASALR---------------------LDED--SEHPPMILRTD------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AY57-1", "uniprot_id": "WIPI2_RAT", "id": "Q6AY57-1", "name": "WD repeat domain phosphoinositide-interacting protein 2", "aln": "-------MNLAS-QSGEAG--AGQLLFANFNQDNT------------------SLAVGSKSGYKFFSLSSVD-----------KLEQIYECTDTEDVCIVERLFSSSLVAIVS----LKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEES-LYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDAS---GTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASS-NTETVHIFKLEA-VREK-----PPEEPTTWTGY--FGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLTTIQKIPRLLVGA--SDGYLYMYNLDPQEGGECALMRQHRLDGSMETTSEIVDSASHDCPLVTQTYGTAAAKGAYVPSSPTRLGKGQDANLEAYTD--------------DLGAVGGACLEDEASALR---------------------LDED--SEHPPMILRTD------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y4P8-1", "uniprot_id": "WIPI2_HUMAN", "id": "Q9Y4P8-1", "name": "WD repeat domain phosphoinositide-interacting protein 2", "aln": "-------MNLAS-QSGEAG--AGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSSVD-----------KLEQIYECTDTEDVCIVERLFSSSLVAIVS----LKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEES-LYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDAS---GTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASS-NTETVHIFKLET-VKEK-----PPEEPTTWTGY--FGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGA--ADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRL---------AYTD--------------DLGAVGGACLEDEASALR---------------------LDED--SEHPPMILRTD------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P910-1", "uniprot_id": "A0A8M1P910_DANRE", "id": "A0A8M1P910-1", "name": "", "aln": "-------MNLAS-QSGEAG--CSQLLFANFNQDNT------------------SLAVGTKSGYKFFSLSSVD-----------KLEQIYECTDTEDVCIVERLFSSSLVAIVS----LKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEES-LYIHNIRDMKVLHTIRETPPNPSGLCALSISNDNCYLAYPGSATIGEVQVFDTVNLRAANMIPAHDSPLAALAFDAS---GTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMEGLYLSASS-NTETVHIFKLET-QREKSV---PQEEPTTWTGY--FGKVLMASTTYLPAHVTEMFTQGRAFATVRLPFSGHKNICALAIIQKIPRLLVAA--ADGYLYLYNLDPQEGGECTLMKQHKLDGSAEPANEILEQTAHDRPLVAQTYSAAVAKG--------------------YSE--------------DQGAVGGAGVEDDMNTLH---------------------LDEE--NEQPPLILETD------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8R3E3-1", "uniprot_id": "WIPI1_MOUSE", "id": "Q8R3E3-1", "name": "WD repeat domain phosphoinositide-interacting protein 1", "aln": "-------MEAEA-ADAPPGRVEAALSCFSFNQDCT------------------SLAIGTKAGYKLFSLSSVE-----------QLDQVHGSNEIPDVYIVERLFSSSLVVVVS----HTKPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEES-IYIHNIKDMKLLKTVLDIPSNPTGLCALSINHSNSYLAYPGSQSTGEIVLYDGNSLKTVCTIAAHEGTLAAITFNSS---GSKLASASEKGTVIRVFSVPEGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASS-NTETVHIFKMEH-LTDS-----RPEEPSTWSGY--MGKMFMAATNYLPAQVSDMMNQDRAFATGRLNFSGQKNICTLSTIQKLPRLLVAS--SDGHLYIYNLDPQDGGECVLIKTHSLLSSGTTE---ENKENDLRPSLPPSYAATVARPSTSAASTVPG----------YSE--------------DGGALRGEVIPEHEFATG------------------PVCLDDE--NEFPPIILCRGSQKGKTKQS---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5MNZ9-1", "uniprot_id": "WIPI1_HUMAN", "id": "Q5MNZ9-1", "name": "WD repeat domain phosphoinositide-interacting protein 1", "aln": "-------MEAEA-ADAPPGGVESALSCFSFNQDCT------------------SLATGTKAGYKLFSLSSVE-----------QLDQVHGSNEIPDVYIVERLFSSSLVVVVS----HTKPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEES-IYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNAS---GSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASS-NTETVHIFKLEQ-VTNS-----RPEEPSTWSGY--MGKMFMAATNYLPTQVSDMMHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVAS--SSGHLYMYNLDPQDGGECVLIKTHSLLGSGTTE---ENKENDLRPSLPQSYAATVARPSASSASTVPG----------YSE--------------DGGALRGEVIPEHEFATG------------------PVCLDDE--NEFPPIILCRGNQKGKTKQS---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8L2Q1U4-1", "uniprot_id": "A0A8L2Q1U4_RAT", "id": "A0A8L2Q1U4-1", "name": "WD repeat domain phosphoinositide-interacting protein 1", "aln": "-------MEAEA-ADAPPGRVEAALSCFSFNQDCT------------------SLAIGTKTGYKLFSLSSVE-----------QLDQVHGSNEIPDVYIVERLFSSSLVVVVS----HTKPRQMNVYHFKKGTEICNYCYSSNILSIRLNRQRLLVCLEES-IYIHNIKDMKLLKTLLDIPSNPTGLCALSINHSNSYLAYPGSQSTGEIVLYDGNSLKMVCTIAAHEGTLAAITFNSS---GSKLASASEKGTVIRVFSVPEGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASS-NTETVHIFKLEQ-LTDS-----RPEEPSTWSGY--MGKMLTAATNYLPAQVSDMMNQDRAFATGRLNFSGQKNICTLSTIQKLPRLLVAS--SDGHLYIYNLDPQDGGECVLIKTHSLLSSGTAE---ENKENDLRPSLPPSYAATVARPSASTASTVPDNL-----VPWKSEGQNEAVLTRSLPQKSGQPLSGGFGKNKESGRNGMQSMLWAERGGRQEAWAPHCLSHRPWSAPLPKPLSLGCQWARRMLESHNAIQATV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M9PER1-1", "uniprot_id": "M9PER1_DROME", "id": "M9PER1-1", "name": "", "aln": "------MMSLLGRTDVDAG-----EVFVNFNQNIT------------------SLAVATSGGYSLYSLGSVDS----------TLDKIYHTK-SDELFLIERLFESSLVAIVS----QRAPRKLKVCHFKKQSEICNYSYANTILAVKLNRERLIVCLEES-LYIHNIQDMKVVHTIRDTPCNPQGLCALSSSSEHCYLAYPGSVTAGEVQIFDAINLHAKTMIPAHDTPLAALAFSPS---GTEIATASERGTVIRVFSSQDGSRLFELRRGLKRCVSIVSLSFSTCAEYLVSSS-NTETVHIFRLDRSATETAEGHGSKQSSDDWMGYSFFRFLSKTVTSYLPTQVTDVFSQGRAFASVTLPEAGVRRMCAIATIQKQLRLLIAS--QDGYLYVYSIPTVEGAECQLIKRHDLRLEDHYA---MDIKVDSPQTLGLNSGVSIGGAAGVPPSSAS----------------------------AAGAGTGGSGGDGKSAVS-----------------VTGGVDKP--SSSYASAVKGDDPVGPSSA----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02887-1", "uniprot_id": "ATG21_YEAST", "id": "Q02887-1", "name": "Autophagy-related protein 21", "aln": "MKVLQFNQDATCCVVAASSHQISIFNCDPFGKCFEIDTKNSKKKTSNNNGSASNSESRNNEESILITNGSRDRTDAEEEEDNEDNALVTGNILKEGEFVIEMLFSTSLIAIADRGQGLNKGKKLKIVNTKRKCTICEIVFPHEIVDVVMNRKRMCVLLESDQIFIYDISCMKPLETIDLWEDHYKRSQANSFSNASNTGTLEGDSANLNRVATNLLANATQKSVNGSNPSVRTRRNSLRSKIRPRMVLSNDDRSILCFTAYSSPKKNKPNSEALYDVVIYDTLNVTPVNYLNSVHKGNVACLAVSHDGKLLATASDKGTIIRVFHTGVDSDYMSSRSLFKEFRRGTRLCNLYQLAFDKSMTMIGCVGDTDTIHLFKLDDASNSLPGDNSSNGHWNEEEYILASNSNPSMGTPKEIPLSKPRIANYFSKKIKS-SIPNQNLSRNFAYITVNESNRSCLG-------------------------FPDEFPNQVYIASDDGTFS--------------------IYSIP--SKPGECVLTKNNKFT--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. *.: . .. : : .* : : ::* **.:**:.:.. ::::: : *: **: :. *: : :**:*: * **.. ::*::* ** :.*: : * * . : *. : : : : . : .: : . ..:. :.: ::: . : . .: ..: * :* .: . *. : : : . . : ::: :: : : * : ::. . * . .*: . ...: : : : . . . . . . . . . : . ", "identical_positions": 31, "similar_positions": 123, "identity": "5.56%" }, { "cls_id": "homologset.agr.SGD:S000006022", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M086-1", "uniprot_id": "F1M086_RAT", "id": "F1M086-1", "name": "Elongator complex protein 4", "aln": "----------------------MAAAATCGAG-TLSSECVASEAGQSRTSSFQRRG-KASGAPGGGPRLLSIAGTRPSVRNGQLLVSTGLPALDQLLG-GGLAVGTLLLIEEDKYNIYSPLLFKYFLAEGIVN---GHTLLVASAKENPANILQELPAPLLDDNGKKEL-EDVHSAKPPEADANMKIAWRYQLQPRMEQVGPVLSSRFGHYYDVSRRIPQELLE---------SSNWHGFFLPEHTPPGLKGEPCFLSCG-------------------------------------------------------------YMKLLQFFQNIIYTEGFDGANPQKKQKNILRIGIQNLGSPLWGDDICCKEN--SDNHHRLTKFLYILRG--LLRSSLSACIITMPAQLVQ--NKAITTRVRNLSDTVVGLESFIGSERETNPLYKDYHGLIHIRKIPRLNNLTCDESDVKDLAFKLKRKLFTIERLHLPPDLSDTVGRSSRQDLAPSTTLLGTGCSGMTGGKKRLDF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1M7K9-1", "uniprot_id": "F1M7K9_RAT", "id": "F1M7K9-1", "name": "Elongator complex protein 4", "aln": "---------------------MFSASETCYELRRLLLECVASEAGQSRTSSFQRRG-KASGAPGGGPRLLSIAGTRPSVRNGQLLVSTGLPALDQLLG-GGLAVGTLLLIEEDKYNIYSPLLFKYFLAEGIIN---GHTLLVASAKENPANVLQELPAPLLDDNGRKEL-EDVHSTKPPEADANMKIAWRYQLQLRMEQVGPVLSSRFGHYYDVSKRIPQELLE---------SSNWHGFFLPEHTPPGLKGEPCFLSCG-------------------------------------------------------------YMKLLQFFQNIIYTEGFDGANPQKKQKNILRIGIQNLGSPLWGDDICCKENKNSDNYHRLTKFLYILRG--LLRSSLSACIITMPAQLVQ--NKAITTHVRNLSDTVI----------------------------PRLNNLTCDESDVKDLAFKLKRKLFTIERLHLPPDLSDTVGRSSKQDPAPSTTLLGTGCSGMTGGKKHLDF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER73-1", "uniprot_id": "ELP4_MOUSE", "id": "Q9ER73-1", "name": "Elongator complex protein 4", "aln": "----------------------MAAADTCGAG-TLSSRSVASEAGQGGTSSFQRKG-KASGGPGGGPRLLSIAGTRPSVRNGQLLVSTGLPALDQLLG-GGLAVGTLLLIEEDKYNIYSPLLFKYFMAEGIIN---GHTLLVASAKENPAKILQELPAPLLDDNSKKEL-EDVHSAKTPEPNVNMKIAWRYQLQPKME-VGPVSSSRFGHYYDLSKRIPWELLQ---------SSKWHGFFLPEHISPDLKGESCFLSCG-------------------------------------------------------------YMRLLEFIQKSVYAEGFDGANPQKKQKNILRIGIQNLGSPLWGDDICCKEN--CDNNHRLTKFLYILRG--LLRSSLSACIITMPAHLVQ--NKSITTRVRNLSDTVVGLESFIGSERETNPLYKDYHGLIHIRKIPRLNNLTCDESDVKDLAFKLKRKLFTIERLHLPPDLSDTVGRSSKQDLAASTARLGAGCSSMAEGKKHLDF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EB1-1", "uniprot_id": "ELP4_HUMAN", "id": "Q96EB1-1", "name": "Elongator complex protein 4", "aln": "----------------------MAAVATCGSVAASTGSAVATAS-KSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLG-GGLAVGTVLLIEEDKYNIYSPLLFKYFLAEGIVN---GHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKME-IGPVSSSRFGHYYDASKRMPQELIE---------ASNWHGFFLPEKISSTLKVEPCSLTPG-------------------------------------------------------------YTKLLQFIQNIIYEEGFDGSNPQKKQRNILRIGIQNLGSPLWGDDICCAEN--GGNSHSLTKFLYVLRG--LLRTSLSACIITMPTHLIQ--NKAIIARVTTLSDVVVGLESFIGSERETNPLYKDYHGLIHIRQIPRLNNLICDESDVKDLAFKLKRKLFTIERLHLPPDLSDTVSRSSKMDLAESAKRLGPGCGMMAGGKKHLDF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q566Y1-1", "uniprot_id": "ELP4_DANRE", "id": "Q566Y1-1", "name": "Elongator complex protein 4", "aln": "----------------------MAAP----------VRGMAVSSSIGNTTSFQKKT---------RSKLVFIPGTRPSVQNGQLLVSSGVSSLDYVIG-GGLAVGTLLLVEEDRYDSYSRMLLKYFLAEGIVC---GHELFLASARDHPDQIMQELPSPILDDVASMKMSEGQSQPNDPDNPDTMKIAWRYQNQPRVQ-TALASSSRFGHYYDASKTMDPELLQ---------AAKYHSFYQLQETP--VTTGLSSLPSP-------------------------------------------------------------YLALLKSIQTLIQKEGFDGSTPQLRGRNVLRVGLHSLGSVLWGDDVCCKDN--SAHCHALSTFLYALRG--LLRTSLSVAMMTVPSHLIQ--SRAVMGRIIRLSDTAIALESFRGSEKETNPLYKDYHGLLYVRQIPRLNCLTSEVPDTKDLAFKLKRKQFTIERLHLPPDLSETVSRVSKADLAA-------GCASTATGNKHLHF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMQ7-1", "uniprot_id": "ELP4_DROME", "id": "Q9VMQ7-1", "name": "Elongator complex protein 4", "aln": "------------------------------------------------MTSFRKRT-----------VQKPIRGTRTSPHTAQVITSSGNPYLDVVIG-GGLPMGSICLIEEDRFMTHAKVLAKYFLAEGVIS---KQEIFLGSLDDIPAEMLRRLPRPLTDQESMEQS--EVQALGDAGAENGLRIAWRYNDLPLVN--SEHATAKIGHHFNLMEQMDSMMLYNVKTTLWDDSPKHLDIVIDEEFSKSSSPTTPSLEQQPVEDAPPIPGTETAPQEKMPAQEEENSANNNNNNNNNSSSVTSSTKTGSQDSPLQVFHNPRYKGLLNDIQQLLRNESFVAGTKN----NLCRVCLTSLGSPLWYDEHFGEDL---------IKFLTLLMA--SVRNCNSVCLITMPMHLIAKYDASLVPKIRQLVDYAIELESFAGSERETHPAFKEYSGLLHLHKMSAINTLAVHMPETPDLAFKLRRKKFIIEKFHLPPELQESSAKPDN---------CISGLLSNSNATASLDF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02884-1", "uniprot_id": "ELP4_YEAST", "id": "Q02884-1", "name": "Elongator complex protein 4", "aln": "MSFRKRGEILNDRGSGLRGPLLRGPPRTSSTPLRTGNRRAPGNVPLSDTTARLKKLNIADESKTKMGLDSSHVGVRPSPATSQPTTSTGSADLDSILGHMGLPLGNSVLVEEQSTTEFHSILGKLFAAQGIVHNRISDSSADKTRNGDTHVIVLSLNQMFAKELPGIYKGSRKQMKKNLISEEESKVTVQNLNETQRSTPSRYKDLKIAWKYKLADEKRLGSPD---------RDDIQQNSEYKDYNHQFDITTRLMPAP----------------------------------------------------------IASELTFIAPTQPVSTILSQIEQTIKRNDKKLIRIVIPSLLHPAMYPPKMFESSEIIGLMHGVRSLVKKYYERVVLFASISIDIITPPLLVLL---RNMFDSVINLEPFNQEMTEFLERVYKSQPG-KIQHGLVHILKLPVFTDRGEMRVLKSEWAFKNGRKKFEIEQWGIPVDDAEGSAASEQSHSHSHSDEISHNIPAKKT-KISLDY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :: *.*.* ..* .*:* . ** ::* **.:*. *:**: . :* * * *:*:: . : . :: * : .: ::: : . . ::. :. . :. : :: * . . : :: *: : .* . .:: : . * ::* * :: : : * . :. : *** ** * **: :* : : . .. . . *.:", "identical_positions": 38, "similar_positions": 83, "identity": "7.2%" }, { "cls_id": "homologset.agr.SGD:S000006024", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q769K2-1", "uniprot_id": "NAPEP_RAT", "id": "Q769K2-1", "name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D", "aln": "-----------------------------------------MDENENSQSPAPSHQYPKETLRKRQNSVQNSGGSESSRLSRKSFKLDYRLEED----------VTKSKKGKDGRFVNPWPTWKNVSIPNVLR---WLIMEKDHSSVPGSKEELDKELPVLKP---------------------------YFISDPEEAGVREAGLRVTWLGHATLMVEMDELILLTDPMFSSRASPSQYMGPKRFRRPPCTISELPPIDAVLISHNHYDHLDYGSVLALNERFGSELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPG-HDKVTFVFTPSQHWCKRTLLDDNKVLWGSWSVLGPWN-RFFFAGDTGYCP-AFEEIGKRFGP-FDLAAIPIGAYEPRWFMKYQHADPEDAVRIHIDVQAKRSVAIHWGTFALANEHYLEPPVKLNEALERYGLKSEDFFILKHGESRYLNTDDKAFEET", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH82-1", "uniprot_id": "NAPEP_MOUSE", "id": "Q8BH82-1", "name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D", "aln": "-----------------------------------------MDEYEDSQSPAPSYQYPKETLRKRQNSVQNSGGSVSSRFSRKSFKLDYRLEED----------VTKSKKGKDGRFVNPWPTWKNISIPNVLR---WLIMEKNHSGVPGSKEELDKELPVLKP---------------------------YFVSDPEDAGVREAGLRVTWLGHATLMVEMDELIFLTDPMFSSRASPSQYMGPKRFRRPPCTISELPTIDAVLISHNHYDHLDYGSVLALNERFGSELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPG-HDKVTFVFTPSQHWCKRTLLDDNKVLWGSWSVLGPWS-RFFFAGDTGYCP-AFEEIGKRFGP-FDLAAIPIGAYEPRWFMKYQHADPEDAVRIHIDLQTKRSVAIHWGTFALANEHYLEPPVKLNEALERYGLSCEDFFILKHGESRYLNTDDRAFEET", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IQ20-1", "uniprot_id": "NAPEP_HUMAN", "id": "Q6IQ20-1", "name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D", "aln": "-----------------------------------------MDENESNQSLMTSSQYPKEAVRKRQNSARNSGASDSSRFSRKSFKLDYRLEED----------VTKSKKGKDGRFVNPWPTWKNPSIPNVLR---WLIMEKDHSSVPSSKEELDKELPVLKP---------------------------YFITNPEEAGVREAGLRVTWLGHATVMVEMDELIFLTDPIFSSRASPSQYMGPKRFRRSPCTISELPPIDAVLISHNHYDHLDYNSVIALNERFGNELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPG-HDKVTFVFTPSQHWCKRTLMDDNKVLWGSWSVLGPWN-RFFFAGDTGYCP-AFEEIGKRFGP-FDLAAIPIGAYEPRWFMKYQHVDPEEAVRIHTDVQTKKSMAIHWGTFALANEHYLEPPVKLNEALERYGLNAEDFFVLKHGESRYLNNDDENF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8RJ40-1", "uniprot_id": "A0A2R8RJ40_DANRE", "id": "A0A2R8RJ40-1", "name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D", "aln": "-----------------------------------------MAEQP------------------------LVGASSST-------PLDYRQEAD----------VTCSRRDSQGRFVNPWSTWHFPSYTTVAR---LFLTEKNNSKIPSAKEALDRELPIVQP---------------------------YFIQNPDQCGQTGTSVRATWLGHATVLVEMEGLLVLTDPIFSQRASPVAFMGPKRYRDPPCTIEQLPRLDAVVISHTHYDHLDAASVTALNSRFGSALHWFVPLGLAEWMQKTGCENVTELDWWVGSRIPG-HDNVSFFCTPAQHWCKRTPVDDNKTLWGSWSIVGSHS-RFFFAGDTGYCA-SFKEIGRHFGP-FDLAAIPIGAYVPRGIMKSQHVDPEEAVQIHIDVQAKASLAIHWGTFPLSYEHYLEPPARLREAMVNLGLNPDDFFTLHHGESRMINLKDMHSSS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02883-1", "uniprot_id": "FMP30_YEAST", "id": "Q02883-1", "name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D, mitochondrial", "aln": "MNFVTCHVQMRLLLQRRLVRLRESELFRPQTSLSTFKRHASQKTRPIQKCSRKYARILLLSVLVPYTGYAFYVSLATVKQIDLRNEMCQRLEENNNEVTYKGSLLKYSPLEVLGRFENPFEEYRIQTVFEFFANRVFELFERNRGGIPRDVHQMNKLMPVHKPTWGPNLVDVDPAEETALPLECKVLDELHIPTAVEENEGSKCPVYNTWLGQSCNYTVYNGLRILTDPLFSD-FLIHKTLGPKRITQMPSQITEVPKPDIILVSHNHPDHLDLESLEYWSGKD--SPLWIVPKGMKSYMTSNGCDNVLELSWWETLQVKKNNEIYHISATPAMHWSGRSLLDTNKSLWCSFLLTHHGNPILFHAGDTGYVKDLFVRIKERFGKGCKLALLPCGQYCPEWHQKPRHINPQEVLKIMKDLEARNVLGVHWGTFVLSGEYFLEPKEKL-EMLAEWGGFKDRCYCPELGKTECFD---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : * * : :. * *** **: :: : . : *::.. :* . ::: :*: :* :: :: : ****:: . : * .****:**. :**** *. * ::* * :::**.* **** *: . : *:** *: .:* . **:** **.** : :: : **: **. *: :* ** ** *: : . :*.****** * .* .:** .** :* * * *. * :* :*::.::* *:::: :.:***** *: *::*** :* * : . * : : . *::. :: ", "identical_positions": 99, "similar_positions": 101, "identity": "20.58%" }, { "cls_id": "homologset.agr.SGD:S000006025", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3KRD0-1", "uniprot_id": "SYDM_RAT", "id": "Q3KRD0-1", "name": "Aspartate--tRNA ligase, mitochondrial", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYLGSWLN--------RLGRG-----------------LSRPIGKTKQPIWGSLSR---------------------------------------------------------------------------------SLTLSSQR-VPEFSSFVARTNTCGELRSSHLGQEVTLCGWIQYR-----RQNTFLVLRDCHGLVQILIPQDESAASVRRTLCEAPVESVVRVSGTVIARPLGQENPKMPTGEIEIKAKTAELLNACKK-LPFEIKDFVKKTEALRLQYRYLDLRSSQMQHNLRLRSQMVMKMREYLCTLHGFVDIETPTLFKRTPGGAKEFLVPSREPGR-----FYSLPQSPQQFKQLLMVGGLDRYFQVARCYRDEGSRPDRQPEFTQIDIEMSFVDQTGIQHLVEGLLHYSWPED-------------------KDPLVAPFPSMTFAEALATYGTDKPDTRFGMKIVDISDVFRN-TEIRFLQDALAKPQGTVKAICVHEGAKYLRKEDIEFIRKFAAHHFSQEVLPIFLNARKNWSSPFAKFITEEERLELTRLMEIQEDDMVLLTAG--QHEKACSLLGKLRLECADLLETRGLALRDPA-LFSFLWVLDFPLFL---------------AKEESPTELESAHHPFTAPHPGDIHLLYTEPE---KVRGQHYDLVLNGNEIGGGSIRIHDAQLQRYILETLLKED--VKLLSHLLQALDYGAPPHGGIALGLDRLVCLVTGAPSIRDVIAFPKSYRGHDLMSNAPDTVSPEDLKPYHIHVSWP--------------TDSEER-ASATPSKYLSS---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BIP0-1", "uniprot_id": "SYDM_MOUSE", "id": "Q8BIP0-1", "name": "Aspartate--tRNA ligase, mitochondrial", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYLGFWLS--------RLCRG-----------------LSRPIGKTMRPIWGSLSR---------------------------------------------------------------------------------NLALSSQR-IPEFSSFVARTNTCGELRSSHLGQEVTLCGWIQYR-----RQNTFLVLRDCHGLVQILIPQDESAASVRRILCEAPVESVVRVSGTVISRPPGQENPKMPTGEIEIKVKTAELLNACKK-LPFEIKDFVKKTEALRLQYRYLDLRSFQMQYNLRLRSQMVMKMREYLCNLHGFVDIETPTLFKRTPGGAKEFLVPSREPGK-----FYSLPQSPQQFKQLLMVGGLDRYFQVARCYRDEGSRPDRQPEFTQIDIEMSFVEQTGIQRLVEGLLQYSWPGD-------------------KDPLVTPFPSMTFAEALATYGTDKPDTRFGMKIVDVSDVFRN-TELRFLQDALAKPQGTVKAICVHDGAKYLRKEDIEFIRKFAVHHFSQEVLPIFLNAKKNWSSPFAKFIMEEERLELARSMEIQEEDIVLLTAG--EHEKACSLLGKLRLECADLLEMRGAVLRDPA-VFSFLWVVDFPLFL---------------AKEESPTELESAHHPFTAPNSSDIHLLYTEPE---KVRGQHYDLVLNGNEIGGGSVRIHDAQLQRYILETLLKED--VKLLSHLLQALDYGAPPHGGIALGLDRLVCLVTGAPSIRDVIAFPKSYRGQDLMSNAPDSVSPEELKPYHIHVLWP--------------ADSEEESASATPSKHLSS---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PI48-1", "uniprot_id": "SYDM_HUMAN", "id": "Q6PI48-1", "name": "Aspartate--tRNA ligase, mitochondrial", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYFPSWLS--------QLYRG-----------------LSRPIRRTTQPIWGSLYR---------------------------------------------------------------------------------SLLQSSQRRIPEFSSFVVRTNTCGELRSSHLGQEVTLCGWIQYR-----RQNTFLVLRDFDGLVQVIIPQDESAASVKKILCEAPVESVVQVSGTVISRPAGQENPKMPTGEIEIKVKTAELLNACKK-LPFEIKNFVKKTEALRLQYRYLDLRSFQMQYNLRLRSQMVMKMREYLCNLHGFVDIETPTLFKRTPGGAKEFLVPSREPGK-----FYSLPQSPQQFKQLLMVGGLDRYFQVARCYRDEGSRPDRQPEFTQIDIEMSFVDQTGIQSLIEGLLQYSWPND-------------------KDPVVVPFPTMTFAEVLATYGTDKPDTRFGMKIIDISDVFRN-TEIGFLQDALSKPHGTVKAICIPEGAKYLKRKDIESIRNFAADHFNQEILPVFLNANRNWNSPVANFIMESQRLELIRLMETQEEDVVLLTAG--EHNKACSLLGKLRLECADLLETRGVVLRDPT-LFSFLWVVDFPLFL---------------PKEENPRELESAHHPFTAPHPSDIHLLYTEPK---KARSQHYDLVLNGNEIGGGSIRIHNAELQRYILATLLKED--VKMLSHLLQALDYGAPPHGGIALGLDRLICLVTGSPSIRDVIAFPKSFRGHDLMSNTPDSVPPEELKPYHIRVSKP--------------TDSKAERAH------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PDL2-1", "uniprot_id": "M9PDL2_DROME", "id": "M9PDL2-1", "name": "", "aln": "MLLISRTLWRSHQRLQLQQQLVHSASSGGFLADRHIRHRSTPDSLFSAKEPADCGHIMSGRYRGGGGGRFGGRGGGGYADGGGYNDFDNYRGGGGPGFNDNFGPGPGPNPFNMGGPNISGNELMQLMSAMASNFNMNSQPPQPMRQSCGELRNHHCGLFVELSGRLIKKRVNRFAELRDRNGGACQLVVLEDKHPRVARRMNNMPENTTLTIVGLVMRRPHNSCNQTMPTGEIEVEVQDILNIHFPAGGTKRAGDKRTYSTMVQQQSNLGITSTEYKIAKNENILKYFENRDLTCNDLRRDDVGKTVTLVGWIPSTKNNKFLQLKDGYGQTQLMIEDQSLSDTFLSTPEQTVIQIVGKVLGRPKANVNLKYDTGEVEVSVTSVKVLNPDDPYDGPIKAKEKKQKFSIDDLEAEEAAAEASANLTSNNGESTEDSAEASTTANASLIAEQRAKVADTNKFADRTHNCGELTSNDINEKVVICGWLEFQ-----RMNKFFILRDAYGQTQVLLSP-KTYGLEEYAETGVPIESIVRVEGTVIPRPAATINPKMQTGHVEVEADKVVVLNPAKKNLPFEIRKFNRAGERLRLTHRYLDLRFNDMQHNLRLRSAVIMKMREYLINYLGFVEVETPTLFRRTPGGAQEFVVPTRKAGH-----FYSLVQSPQQFKQMLMSGGIDRYFQVARCYRDEATRPDRQPEFTQLDIELSFTSRDDIMQLIEETLRYSWPKD-------------------FPRLQTPFRRITYEEAMEKYGNDKPDTRFGFLLNNVSEIIEKSDEFKEKYDDLG-----AYAIVVRASEAFWNGAARKHYESLG-KEFKGTLFVRKFGPTKDVQEKLGKLLGEDVATEVADKFDLEENDLLFLGIG--SKVETRELLGRIRLDYQDFLVEN-AKIKKPN-DFRFLWVIDFPLFE---------------RNRETN-QLESVHHPFTLPHSDDLENFATSCENLESIRSQAYDLVLNGQEVGGGSIRIHDRDMQHFILEQILKIP--HDHLSHLLSALESGCPPHGGIALGLDRLIAILCRARSIRDVIAFPKSLNGRDPLSNAPVPISDEEMRLYHLSVVDEEEPSTNNTSHEQEDDDPDQERAPPSPMSATSESEQPQINVDIKQEPEGLNEDFAPESPATKSTVKADPDEPSPSNPLASEAATPARARRTVKKKV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15179-1", "uniprot_id": "SYDM_YEAST", "id": "P15179-1", "name": "Aspartate--tRNA ligase, mitochondrial", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLARSRVCLQTITRRLAD------------------------------------------------------------------------------------FPEANAIKKKFLFRKDTSTIKQLKGLSSGQKIVLNGWIEQKPKRVGKNLIFGLLRDSNGDIIQLVDN-------KSLLKGFTLEDVVQAVGILSLKRKLSNE---DADEYEVQLEDITVLNASNK-KPAQMQDFKLS-AIYPPEFRYLQLRNPKYQDFLKKRSSISKEIRNSFNNFD-FTEVETPMLFKATPEGAREFLVPTRTKRSDGKPSFYALDQSPQQYKQLLMASGVNKYYQMARCFRDEDLRADRQPEFTQVDMEMAFANSEDVMKIIEKTVSGVWSKFSKKRGLLTLDSKGTLVPAKKENGTVSIFRMTYEQAMTSYGIDKPDLRAPDLKIINLGEFNAFSHLNKKFPVFEVIILRSAFSNMEEYKERWS--FLTNNSNYNYRVPIVLPIENDEQANSNWFENFHAIATFENPHLITKFLKLKKGDIVCGCTREPNHSIFENPTPLGRLRQLVLQSEHGKNIYHAVNKDVASWIVDFPLFSPVIIEDKSGKKEKLAYPEYEKDRLCSTHHPFTMVKLKDYEKLEKTPE---KCLGRHYDLVVNGVELGGGSTRIHDPRLQDYIFEDILKIDNAYELFGHLLNAFDMGTPPHAGFAIGFDRMCAMICETESIRDVIAFPKSITGADLVVKSPSVIPESILEPYNIKYSNSKK---------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * . : . * * . :* . .:::.: **:: : : * :*** * :: . .:*.:*:. * : : : :.. *:: . :**..:* * :::.* .***:** . * *: ** : ::*: : . *.::*** **: ** **:**:**:* **:* *****:**:** .*:::*:*:***:*** *.********:*:*::*.. .: ::* : *. ..: :*: :.: .** **** * :. .: : : . : . : . . : . : :. :: *:: .: . ** : . : .. *::***** . .* *.***** : * . : . : . .: ****:** *:**** ***: :* :*: :** . :.***.*:: * ***.*:*:*:**: .:: : *********** * * : ::* :. . :. *:: ", "identical_positions": 151, "similar_positions": 169, "identity": "12.61%" }, { "cls_id": "homologset.agr.SGD:S000006026", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LD97-1", "uniprot_id": "A0ABK0LD97_RAT", "id": "A0ABK0LD97-1", "name": "", "aln": "--MAAETLNFGPEWLRALSSGGS--------------------VASPPPSPAMPKYKLADYRYGREEMLALYVKENKVPEELQDKEFAAVLQEEPLQPLALEPLTEDEQRNFSLSVNSVAVLRLMGKG-AGPPLAATSRGRGSTRS-RGRGRGDSCFYQRSIEEGDGAFGRNP-REIQRSQSWDDRGERRFEKSARRDGGMRVLDVVASRVGRQPRWGSQVECGRETGVSYLEALPYLLFVSPVPVRSGFEE---GGAGPRKEHARSDSENWRSLREEQEDD--SSWRLGAGPRRDGDRWRS------------TSPDGGPRSAGWREHGE-------------RRRKFDFDLRGERGGCGEEDGRVGGGNSHLRRCRG---------LDGFEDDKDGLPEWCLDDEDEEMGTFDASGAFLPLK-----KGPKEPIPEEQELDFQGLEEEEEE-----PSDGVDEEGPEAGGKEVTPLPPSE-KSSSPSSLP-------ALGPLWTANEDG-EAVEKELPPAEGDEMRG----------------------------------------------LPLSPRISSPPA--------------------------GPPADLEDEEGLKHLQQEAEKLVASLQDSSLEEEQFTAAMQTQGLRHSTAATALPLSHGAARKWFYKDPQGEIQGPFTTQEMAEWFQAGYFSMSLLVKRGCDEGFQPLG---EVIKMWG-RVPFAP-------------------------------GPSPPPLLGNMDQERLKKQQE---------------------------------LAAAALYQQLQHQHFLQLVGSRQLPQCATLREKAAMGDLTPP-----------------------------------------QQQ-LTTFLQQLQALKTP-----------------RGGDQNLLPTMSRSLSVPDSGPLWDLHTSASSQ------------SGGEASLWDIPINSSTQGPILEQLQLQHKFQ------ERREVELR-----------VKREEEERKRREEKRRQQQQQ-----EEQKRRQEEEELFRRKQV---------------------------------------------------------------------------------------------------------------------------RQQELLLKLLQQQQATNVPVPPAPSSP-------------------------------------------------------------PPLWAGLAKQG------------------------------------------LSMKTLLELQMESERQLHKQPAPREPLRAQAPNHRVQLGGLGTAPLN---------------------QWVSEAGPLWGGPDK--------------------SGGSSSGNLGLWEDTLKSGGSLARSLGLKNSRSSPSLSDSYSHLSGRPVRKKTEE----------------------------EEKLLKLLQGIPRPQDGFTQWCEQMLHTLSTTS-----SLDVPMAVAILKEVESPYDVHDYIRSCLGDTLEAKEFAKQFLERRAKQKASQQRQQQQQQQQQQQQQQQ--------------EAWLSSSSLQTAFQANHST-----KLG--PGEGSKAKRR-ALMLHSDPSILGYSLHGPS-----GEIESVDDY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MR1-1", "uniprot_id": "GGYF1_MOUSE", "id": "Q99MR1-1", "name": "GRB10-interacting GYF protein 1", "aln": "--MAAETLNFGPEWLRALSSGGS--------------------VASPPPSPAMPKYKLADYRYGREEMLALYVKENKVPEELQDKEFAAVLQEEPLQPLALEPLTEEEQRNFSLSVNSVAVLRLMGKG-AGPPLPATSRGRGSTRS-RGRGRGDSCFYQRSIEEGDGAFGRNP-REIQRSQSWDDRGERRFEKPARRDG----------------------------------------------VRSGFEE---GGAGPRKEHARSDSENWRSLREEQEDD--GSWRLGAGPRRDGDRWRS------------TSPDGGPRSAGWREHGE-------------RRRKFDFDLRGERGGCGEEDGRVGGGNSHLRRCRG---------LDGFEDDKDGLPEWCLEDEDEEMGTFDASGAFLPLK-----KGPKEAIPEEQELDFRGLEEEEEEEE--EPSEGVDEERPEAGGKEATPLPPPE-NSSSPSSLP-------ALGPLWTTNEEGGEAVEKELPPAEGDELRG----------------------------------------------LSLSPRISSPP---------------------------GPPGDLEDEEGLKHLQQEAEKLVASLQDSSLEEEQFTAAMQTQGLRHSTAATALPLSHGAARKWFYKDPQGEIQGPFTTQEMAEWFQAGYFSMSLLVKRGCDEGFQPLG---EVIKMWG-RVPFAP-------------------------------GPSPPPLLGNMDQERLKKQQE---------------------------------LAAAALYQQLQHQHFLQLVGSRQLPQCTTLREKAAMGDLTPP-----------------------------------------QQQQLTTFLQQLQALKTP-----------------RGGDQNLLPTMSRSLSVPDSGPLWDLHTSASSQ------------SGGEASLWDIPINSSTQGPILEQLQLQHKFQ------ERREVELR-----------AKREEEERKRREEKRRQQQQQQ----EEQKRRQEEEELFRRKQV---------------------------------------------------------------------------------------------------------------------------RQQELLLKLLQQQQATNVPVPPAPSSP-------------------------------------------------------------PPLWAGLAKQG------------------------------------------LSMKTLLELQMESERQLHKQAAPREPLRAQAPNHRVQLGGLGSAPLN---------------------QWVSEAGPLWGGPDK--------------------SGGSSGGNLGLWEDTLKSGGSLARSLGLKSSRSSPSLSDSYSHLSGRPVRKKTEE----------------------------EEKLLKLLQGIPRPQDGFTQWCEQMLHTLSTAG-----SLDVPMAVAILKEVESPYDVHDYIRSCLGDTLEAKEFAKQFLERRAKQKASQQRQQQQQQQQQQQQ-----------------EAWLSSTSLQTAFQANHST-----KLG--PGEGSKAKRR-ALMLHSDPSILGYSLHGPS-----GEIESVDDY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75420-1", "uniprot_id": "GGYF1_HUMAN", "id": "O75420-1", "name": "GRB10-interacting GYF protein 1", "aln": "--MAAETLNFGPEWLRALSGGGS--------------------VASPPPSPAMPKYKLADYRYGREEMLALYVKENKVPEELQDKEFAAVLQDEPLQPLALEPLTEEEQRNFSLSVNSVAVLRLMGKG-AGPPLAGTSRGRGSTRS-RGRGRGDSCFYQRSIEEGDGAFGRSP-REIQRSQSWDDRGERRFEKSARRDG----------------------------------------------ARCGFEE---GGAGPRKEHARSDSENWRSLREEQEEEEEGSWRLGAGPRRDGDRWRS------------ASPDGGPRSAGWREHGE-------------RRRKFEFDLRGDRGGCGEEEGRGGGGSSHLRRCRA---------PEGFEEDKDGLPEWCLDDEDEEMGTFDASGAFLPLK-----KGPKEPIPEEQELDFQGLEEEEEP------SEGLEEEGPEAGGKELTPLPPQEEKSSSPSPLP-------TLGPLWGTNGDGDETAEKE-PPAAEDDIRG----------------------------------------------IQLSPGVGSSA---------------------------GPPGDLEDDEGLKHLQQEAEKLVASLQDSSLEEEQFTAAMQTQGLRHSAAATALPLSHGAARKWFYKDPQGEIQGPFTTQEMAEWFQAGYFSMSLLVKRGCDEGFQPLG---EVIKMWG-RVPFAP-------------------------------GPSPPPLLGNMDQERLKKQQE---------------------------------LAAAALYQQLQHQQFLQLVSSRQLPQCA-LREKAALGDLTPPPPPPPQQ----------------------------------QQQQLTAFLQQLQALKPP-----------------RGGDQNLLPTMSRSLSVPDSGRLWDVHTSASSQ------------SGGEASLWDIPINSSTQGPILEQLQLQHKFQ------ERREVELR-----------AKREEEERKRREEKRRQQQQE------EQKRRQEEEELFRRKHV---------------------------------------------------------------------------------------------------------------------------RQQELLLKLLQQQQA--VPVPPAPSSP-------------------------------------------------------------PPLWAGLAKQG------------------------------------------LSMKTLLELQLEGERQLHKQPPPREPARAQAPNHRVQLGGLGTAPLN---------------------QWVSEAGPLWGGPDK--------------------SGGGSSG-LGLWEDTPKSGGSLVRGLGLKNSRSSPSLSDSYSHLSGRPIRKKTEE----------------------------EEKLLKLLQGIPRPQDGFTQWCEQMLHTLSATG-----SLDVPMAVAILKEVESPYDVHDYIRSCLGDTLEAKEFAKQFLERRAKQKASQQRQQQQ-------------------------EAWLSSASLQTAFQANHST-----KLG--PGEGSKAKRR-ALMLHSDPSILGYSLHGSS-----GEIESVDDY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q2B5-1", "uniprot_id": "A0A8M9Q2B5_DANRE", "id": "A0A8M9Q2B5-1", "name": "", "aln": "--MTAETLNFGPEWLRALSSGSS--------------------LSSPPASPAMPKYKLAEYRYGREEMLALYVKDNKVPEEMQDKEFAAILQDEPQQPLALLPLTEEEQRNFSMSVNSVAVLRLMGKG-GGAVPAGVNRGRGSVRGGRGRGRGESGFYQRSTEEGEGGFARSV-REIHRSQSWDDRSERRFEKPLRRDG----------------------------------------------VRVGFEE---GAPGVRKEFMRSDSDNWRTLREEQEEE-----DAGETAVSSWRLTVA------------KREDGGPRSAGWREHTGPGE---------VRRRKFDFDFRD-------------GGNEGGRRRAG---------SEGAEDDRDGLPEWCTDEEDGEMGTFDSSGAFMSIK-----KGPKDPILEE---EFQGLEDEEDEGAHQEMKNGMGAEKTEKDVIDSAAVSETEVKLVSPSTPPPPSLPPSLPAPISEAVPSAAPSGLEESPPAPSIPHKLPSEVLSEA-------------------------------------MLDLSPSASSSLPSSPPSLSSAATDL------------PPPGGDIEDDEGMKHLQQEAEKMVAALQDTSLEEECFTQTLQES----RNTASALPLSHDSAMKWFYKDPQGEIQGPFSTVEMCEWFQAGYFAMNLLVKRGCDEGFQPLG---EVIKMWG-RVPFAP-------------------------------GPSPPPLLVRN-QAQLHPQPP---------------------------------RGATGNMDQER------LKKQQELAAATALYQQLQQ-----------------------------------------------QQQ-----QQQLFQLIN------------------RCGEQGMIPSLNRSMSVPDTGSMWDMHTSASQP------------AGGEASIWDL-MNSSSQGPILEQLQ---KLQ------ERREAELR-----------AKREEEERKRRDEKRRE----------EQKRR-EEEEHYRRK-----------------------------------------------------------------------------------------------------------------------------QQQDLLMKLLQQAPRQGSSGSGSSWSS-------------------------------------------------------------GPISG-LGKQS------------------------------------------KPLN-LLDVQQEADR-MHKQ------------QHRVQQQRWSDASS-----------------------LWGAAGSLDGKVGS--------------------SGSSSGGGMGVWDEALKNQSALRNNMGLKNSRSSPSLSEQYMMRG----RKRTEE----------------------------EDRLLKLLQGMK-SQDGFTTWCEQMLHALNTSANNSSSSQDVPIIVAYLKDLESPYEVLNFICSYLGDTVEAKEFARQFLERRAKQKANHQRQQQQLSKEMAGLSMNNFPLQ-------DSVRGMNPSALQSMFQAVHSG-----KGSGVYDQAAKLKKKQPTMLHSDPSILGYSFHGGPDRYGLNEMEMVEDY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6Y7W8-1", "uniprot_id": "GGYF2_MOUSE", "id": "Q6Y7W8-1", "name": "GRB10-interacting GYF protein 2", "aln": "MAAETQTLNFGPEWLRALSSGGS--------------------ITSPPLSPALPKYKLADYRYGREEMLALFLKDYKIPFDLLEKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGGTVVGAPRGRSSSRG-RGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVG----------------------------------------------RPNFEESGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRP------------HSPDG-PRSTGWREHME-------------RRRRFEFDFRDRDD-----------ERGYRRVRSG---------SGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLK-----KVQKEPIPEEQEMDFRPVEEGEERSD-SDSSHNEEAKEPDKTNRREGEKTDR-AGAEASEEVPQTSLSSARPGTPSDHQPQEATQFERKDEPKAEQVEKAEEENRSENSLSAKVPSRGDETVPASQQP--STPLP-PDTASPLLILSPPVPTPSSASRPVETAAVEAPGMS-------------SVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLTSKLQEH----RAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLG---DIMKMWG-RVPFSP-------------------------------GPAPPPHMGELDQERLTRQQE---------------------------------LTAL---YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQ--------------------------------------------QQQQLALLLQQFQALKM------------------RMSDQNIIPSVTRSVSVPDTGSIWELQPAASQP-----------AVWEGGSVWDLPLDTTAPGPSLEQLQQLEKAKAAKLEQERREAEMR-----------AKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR--------------LRHEEEERKRKELELQRQKDLMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTAT--CQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQQKLSGWGNVSKPA------------------------------------------GTTKSLLEIQQEEARQMQK---QQQQQQQQQQQHQQSNRARNSTHSN---------------------LHTSLGNSVWGSINTGPSNQ----WASELVSSIWSNADTKNSNMGFWDDAVKEVGP-----RNSTNKNKNNASLSKSVGVSNRQNKKVEE----------------------------EEKLLKLFQGVNKAQDGFTQWCEQMLHALNTAN-----NLDVPTFVSFLKEVESPYEVHDYTRAYLGDTSEAKEFAKQFLERRAKQKVNQQRQQQQQQQQQQ-----------------DSVWGMNHSTLHSVFQTNQSN----NQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A096MKC0-1", "uniprot_id": "A0A096MKC0_RAT", "id": "A0A096MKC0-1", "name": "", "aln": "MAAETQTLNFGPEWLRALSSGGS--------------------ITSPPLSPALPKYKLADYRYGREEMLALFLKDYKIPFDLLEKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGGTVVGAPRGRSSSRG-RGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVG----------------------------------------------RPNFEESGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRP------------HSPDG-PRSTGWREHME-------------RRRRFEFDFRDRDD-----------ERGYRRVRSG---------SGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLK-----KVQKEPIPEEQEMDFRPVEEGEERSD-SDSSHNEEAKEPDKTNRRDGEKTDR-AGTDANEEVPQTSLSSARPGTPSDHQPQEAAQFERKDEPKAEQMEKAEEESRSENSLPAKIPSRGDETVPASQQP--STQLP-PDTASPLLILSPPLPTPSSASRPVETAAVEAPGMS-------------SVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLTSKLQEH----RAKGVSVPLVHEAMQKWYYKDPQGEVQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLG---DIMKMWG-RVPFSP-------------------------------GPAPPPHMGELDQERLTRQQE---------------------------------LTAL---YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQ--------------------------------------------QQQQLALLLQQFQALKM------------------RMSDQNIIPSVTRSVSVPDTGSIWELQPAASQP-----------AVWEGGSVWDLPLDTTTPGPSLEQLQQLEKAKAAKLEQERREAEMR-----------AKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR--------------LRHEEEERKRKELELQRQKDLMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTT--CQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQQKLSGWGNVSKPA------------------------------------------GTTKSLLEIQQEEARQMQK---QQQQQQQQQQ-HQQSNRARNSTHSN---------------------LHTSIGNSVWGSINTGPPNQ----WASDLVSSIWSNADTKNSNMGFWDDAVKEVGP-----RNSTNKNKNNASLSKSVGVSNRQNKKVEE----------------------------EEKLLKLFQGVNKAQDGFTQWCEQMLHALNTAN-----NLDVPTFVSFLKEVESPYEVHDYTRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQDSVWGMNHSTLHSVFQTNQSN----NQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6Y7W6-1", "uniprot_id": "GGYF2_HUMAN", "id": "Q6Y7W6-1", "name": "GRB10-interacting GYF protein 2", "aln": "MAAETQTLNFGPEWLRALSSGGS--------------------ITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPSDLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGG-TVVGAPRGRSSSRG-RGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVG----------------------------------------------RPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRP------------HSPDG-PRSAGWREHME-------------RRRRFEFDFRDRDD-----------ERGYRRVRSG---------SGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLK-----KVQKEPIPEEQEMDFRPVDEGEECSD-SEGSHNEEAKEPDKTNKKEGEKTDR-VGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQP--LSQIP-SDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMG-------------SVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEH----RAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLG---DIMKMWG-RVPFSP-------------------------------GPAPPPHMGELDQERLTRQQE---------------------------------LTAL---YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQ--------------------------------------------QQQQLALLLQQFQTLKM------------------RISDQNIIPSVTRSVSVPDTGSIWELQPTASQP-----------TVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMR-----------AKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR--------------LRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA--CQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ-KLSGWGNVSKPS------------------------------------------GTTKSLLEIQQEEARQMQK---QQQQQQQHQQ----PNRARNNTHSN---------------------LHTSIGNSVWGSINTGPPNQ----WASDLVSSIWSNADTKNSNMGFWDDAVKEVGP-----RNSTNKNKNNASLSKSVGVSNRQNKKVEE----------------------------EEKLLKLFQGVNKAQDGFTQWCEQMLHALNTAN-----NLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQ---QDSVWGMNHSTLHSVFQTNQSN----NQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4KME6-1", "uniprot_id": "GGYF2_DANRE", "id": "Q4KME6-1", "name": "GRB10-interacting GYF protein 2", "aln": "-MAETQTLNFGPEWLRALAGGVGSS-----------------IVASPPLSPALPKYKLADYRYGREEMLALYVKDNMIPVDLHDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGR--GGGTVAGAPRGRSSSRG-RGRGRGD-GFYQRSFDDVEGGFGRGG-REMHRSQSWEERGDRRFEKPGRKDPDGAPAHFPLNH-----------------------------------IRANYED--PAAVN-ARKFIHAECDNWRTTRDELNGEEDDNGWRLAGARRENERWCP------------PSPDG-PRSAGWREHPD-------------QRRRFGFGDEERS--------------GYRRPRSG---------SGSAEEERDSLPEWCLEDAEEETGTFDSSGAFLSLKVRALEKAPKEPILEEAELDFRPLEENDEYAE-KDDSETEQTKDTDTNTRHESDRNEENCKSEEPSPVAVPFSAVVTPPKATTPAPIQPVHLEKAEDKERPSERTTLPEIRHELSKAPLHTALSNSIVEAISIPHVANKLPDLPVPAPSVLPVKSVPPQSQQVKPIEMPVSVPPALLRSTGSVGPISRPSALPSDLDEDEGLKHFEQEAEKMVAYLQDGGVDDERLASKIGP-------KPSALPITNEAAFKWFYKDPQGEIQGPFNNQEMSEWFQAGYFTMTLQVKRGCDEMFQPLG---EMIKLWG-RVPFTP-------------------------------GPTLPPILGDADQERMKRQQE---------------------------------INALN-MYQLQQMQYQYLLRQQYALQQKVLNSAPPPPPP--------------------------------------------PQQQLNLLLHQALKIRT------------------PEPQQSLLPPVTRSMSVPDSGSVWEMQNPSTQASCSPNMQPAAPSTWEGSSVWDLPLDNMPQASSIEQLQ-LEKAKALKLEMERREAELR-----------AKREEEERKR-------LEEALRARQEEERKRLEEEELARRKQEEALKRQREQEEAQRRKKEEEERLAQEEALRRLEERRREEEERRQREEFLRKQQEEERRKQEELEAQRRREEEKRLEEEAAAAAAAL-----------LRQQQEEQKKREQEAQRQQELQRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSKWGQQSTTANSLSQSQNALSLAEIQKLEEERERQTREEQRRQQ----QELQRVQQQQPQTKLPGWGSVAKQP------------------------------------------MATKSLLEIQREEAQQMKQRKDQQQQQQQQQQPPPQPQPQQHSTNTQQNRTQ----------------NRAAINTSVWGSVNNVSSN-----WMMD--SSVWG--DTQNSNIGFWDEAVKEAAPPQTTRKSHTPKNKGNANLSNSS--SGKASKKVEE----------------------------EEKLLKLFQGANKNQDGFMQWCEQTLHTLNTAN-----NLDVPTFASFLKEVDSPYEVHDYVRAYLGDTPQAKDFAKQFLERRAKQNDNQQKPQQGQQQKQQ-----------------ESVWGIREVPQSVLLQQQQQQQLQQQQQQRFETVTSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETVEDF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KQM6-1", "uniprot_id": "GGYF1_DROME", "id": "Q7KQM6-1", "name": "GIGYF family protein Gyf", "aln": "---MTDSMKFGPEWLRNMSAEPSGSPSTYNVGNAAQNNSIGGHNLGNNTAASASRNLFPEYRYGREEMLSLFDRNCLLPQILP--SFKKLFVEKVQCPLALTPSSEEDINQNSLGNNSRPAWLQRSPSGFGSASRGSGRGGTVDRG---RMRGKSAYHP-IYQRPSGLYDESLSVISKAERTWSDRNGTGDSAATTTSTSGS-------------------------------------------GALDWNGTPSSSPRKDYSNNHRNLENWRRTRNE-DGSGDGPSSSGSMSGPDIAGWRSGVVGGSTNAGFGTNSHRWGRSTSWRDEDPSVDNAASLQRSISTVATLSTDRTGNNKGSGIGAAEGVGSISHPRLSSSKISQLWTVNNAAGVDADENLPEWAIENPSKLGGSFDASGAFHGDTDLKPIKSSHNTLKTKSLDSYDDVKRPKSKDL-SDPDSGNDITPETSLTKDTNTTAVQEEVESSLSPISSTTTKEVIHGDISDRIKEVADEVEKLIMDDDHKISSNQSQHQNHDG------------------------------------FTAALPRMADIEINVKPSVTAVHRQA-------------PSTMPIQITPTITDVAPPSHAVVSFSDHETMQHHNMHHLPQFP-----MIPTPHIITPNLNELWFYRDPQANVQGPFSAVEMTEWYRAGYFNENLFVRRYSDNRFRPLG---ELIKFCHGNMPFTHSHLLPSPIELENIPVGQIPAPLTASLSITPHKPSPIPIALSVVEQQLQQQRDEQLKANVTATAEALRAAIKGSFGGNSIGNTSHLLTMRFQMLQDQYIQHQEYQILAELSKNECFQRLSAVEQETVVRRKVQLLGLPEYLISLNGLSNSLSVLNPVAGRQLYRAVVEHAKKDQQHIFANTEQQRSVGNLLDANNFILNAQIMIQQSQQEVGPLVSSVDCIMQGGTAADLNKPNEIPRN----ELDLINEYNLRMLLRGQPTSTQQQPPALTNSATENLPGVDFLTETQLLERQNLMIPIWLPPNNNKQQETDQQWAEMSNADASLWETANLNEERNEDQQLLIQKSSEACFADTEKDVKIAQLFQVQSGNVVNHTALEELDQSPQNLKGSHNQKIVKSLVSDIQQNHNEELNSHQHQVKQANKQNLNTKQNAAQSALKPINNENDRKREQTEEKKRQREERKRQQLEDDKRRALNESEEQTRQIQEEKERQQQIQAQRRKALLGNVHSLSVQNGMSGTLASAQSKKNDDAKTAEPQVSSRLPSTSVAPWSFQLQNSMRSAPGLAEIQKAERRERRADQQRHQELLDKQLRANAAAAAEANDALLKWQSTPASAPVMSLAEIQAEEARRLANDLVDRQRRRELEHHQQAPLSSAVLVTSATSNIWGNANKAWSSSAAQSLSLKTSSGTGLWDEPNPLGSNGSGTSGTSSVTAAAVLAGGLNSANKSTLQAQNKSSALFASPRNLRKSQTLPALSNPEKSNKNGPGQRPEKQKLAQTRSKGAAVSIEEKDRERKLNAKSQQSSTDQAISKVNEYENEFTSWCIKSLDNMSAKV-------DVPTFVAFLQDLEAPYEVKDYVRIYLGDGKDSLDFAKQFLERRSKYKSLQRAQKAHN------------------------DDMCKPAPAITPSANDYAD-----------SKNKQKKIKKNKMTKMDARILGFSVTAAEGRINVGIRDYVEGP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02875-1", "uniprot_id": "SYH1_YEAST", "id": "Q02875-1", "name": "SMY2 homolog 2", "aln": "-MNPINSLAFDLHSVKLADANSD-------------------------------TAALSNSNTPTMNNAALLQRPSSIMDSIGVQRVPSPFVPGSN---AISGASTVPFNAYDAEITGSPLQISANQENNSAFSAASSNLHMNASS------------PSVLNKPSSTFPNVAPYLYNATGPAPNVGNQPPPP---------------------------------------------------------------GIESQWKYIDSNGNIQGPFGTNNMSQWYQGGYFTPTLQICRLATSP-------------EPFG---------------------------------------------------VNDRFIRLG-----------ELTTLVNNYQDPFVAFDFIVIRALNAVPLVAPTS---------SEKQKVESRDLIPVADVHSDDFTYEEILGLKFEDGSYYHETQVWVPVDGRHITKVDRIPKISAYTAPLSTTSSRSNKTTSSHEEKVPSHEEASPEE-------------------------------------------------------------------------------------QEVFSEEGRTVSNITNEEESIVKNPTKQEEESRGSEKEQNILD----QVQPEIEEVDRKDVISTADEPKSKDTPQMTSEEQKRFAKAELMAQKLLEEQQRQEEEKKRREEQRKLK-----------------------------------------KEKKLKQKQKKEEEKLKKKKK-----------------------------------EEGKLEKEKQKELLNNILTGDTETPSSENTATSITTN----------------------------------------------------LAPWANKKP------------------EGAVYNQISSALEDLKKENSSKKEKKPNRTQLD-------------REQALKLQKEILSSAQIPKTQTGSAWGIKPQQPIKVDIKGELMK-----------DSTKINSQSKINKANNGDIKPDSTFIEEQKKLWEQVQKKTKKFN----------------------------------------------------------------------------------------------------------------------------RASSLDDFISRTPSPSSSALNSSNTS--------------------------------------------------------------NAWTTVSSKS-----------------------------------------TTHIASTMPVAGNQSKSYIS------------------LDTLR---SS---------------------------------------------------------GGLSTATKTKMSDKSKQIGSSTSIPTLKARQVKPSRIPAYPG------------------------------------------------NASVSKRQEFLRWCRSQLKLNTGVQ-----PDNVLEMLLSLPPGSESKEIIADTIYSYSSTMDGRRFATDFIKKRLECEEEIN-------------------------------DPLSWSEVLAMPEGSSED----------WEFQVVGKKKGKRF------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: *. . :: . . :.: . : :* : : : . : *: : . . .. . . . . . . : .. : . : . : . . . : : : . . . :. : :::: . . . . : .. . . . : :... . :* . : . :*:.: :. * .: :* : .* .: :: : :* : :: : : : . : . . . . . : : : . : : .: ::.: :: :. . : : . : : : . . . . . *. . : . .: * ** . *. . :* * . . :: .. :. ** :*:::* : : . * : : ", "identical_positions": 21, "similar_positions": 161, "identity": "1.21%" }, { "cls_id": "homologset.agr.SGD:S000006027", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66HA8-1", "uniprot_id": "HS105_RAT", "id": "Q66HA8-1", "name": "Heat shock protein 105 kDa", "aln": "-MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGPKNRTIGVAAKNQQITHANNTVSSFKRFHGRAFNDPFIQKEKENLSYDLVPMKNGGVGIKVMYMDEDHLFSVEQITAMLLTKLKETAENNLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGIYKQDLPNADEKPRVVVFVDMGHSSFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEHFCAEFKTKYKLDAKSKIRALLRLHQECEKLKKLMSSNSTDLPLNIECFMNDKDVSAKMNRSQFEELCAELLQKIEVPLHLLMEQTHLKTEEVSAIEIVGGATRIPAVKERIARFFGKDVSTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLVWNHDSEETEGVHEVFSRNHAAPFSKVLTFLRRGPFELEAFYSDPQAVPYPE-AKIGRFVVQNVSAQKDGEKSKVKVKVRVNTHGIFTISTASMVEKVPTEEEDGSSVEADMECPNQKPAESSDVDKNIQQDNSEAGTQPQVQTDGQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPVEANLVWQLGRDLLNMYIETEGKMIMQDKLEKERNDAKNAVEECVYEFRDKLCG-PYEKFICEQEHEKFLRLLTETEDWLYEEGEDQAKQAYIDKLEELMKMGTPVKVRFQEAEERPRVLEELGQRLQHYAKIAADFRGKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKRSLHQDPVVRTHEISAKVKELNNVCEPVVTQPKPKIESPKLERTPNGPNMDKKE-DLEGKSNLGADAPHQNGECHPNE--KGSVSMDLD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61699-1", "uniprot_id": "HS105_MOUSE", "id": "Q61699-1", "name": "Heat shock protein 105 kDa", "aln": "-MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNTVSSFKRFHGRAFNDPFIQKEKENLSYDLVPMKNGGVGIKVMYMDEEHFFSVEQITAMLLTKLKETAENNLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGIYKQDLPNAEEKPRVVVFVDMGHSSFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEHFCAEFKTKYKLDAKSKIRALLRLHQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQFEELCAELLQKIEVPLHSLMAQTQLKAEDVSAIEIVGGATRIPAVKERIAKFFGKDVSTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLVWNHDSEETEGVHEVFSRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPE-AKIGRFVVQNVSAQKDGEKSRVKVKVRVNTHGIFTISTASMVEKVPTEEEDGSSLEADMECPNQRPTESSDVDKNIQQDNSEAGTQPQVQTDGQQTSQSPPSPELTSEESKTPDADKANEKKVDQPPEAKKPKIKVVNVELPVEANLVWQLGRDLLNMYIETEGKMIMQDKLEKERNDAKNAVEECVYEFRDKLCG-PYEKFICEQEHEKFLRLLTETEDWLYEEGEDQAKQAYIDKLEELMKMGTPVKVRFQEAEERPKVLEELGQRLQHYAKIAADFRGKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKRSLDQDPVVRTHEIRAKVKELNNVCEPVVTQPKPKIESPKLERTPNGPNIDKKE-DLEGKNNLGAEAPHQNGECHPNE--KGSVNMDLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92598-1", "uniprot_id": "HS105_HUMAN", "id": "Q92598-1", "name": "Heat shock protein 105 kDa", "aln": "-MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKDISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVFSRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPE-AKIGRFVVQNVSAQKDGEKSRVKVKVRVNTHGIFTISTASMVEKVPTEENE-MSSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCG-PYEKFICEQDHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPHQNGECYPNE--KNSVNMDLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61316-1", "uniprot_id": "HSP74_MOUSE", "id": "Q61316-1", "name": "Heat shock 70 kDa protein 4", "aln": "-MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACVSFGPKNRSIGAAAKSQVISNAKNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLSKLKETAESVLKKPVVDCVVSVPSFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNKGKLKVLATAFDTTLGGRKFDEVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDIDVSGTMNRGKFLEMCDDLLARVEPPLRSVLEQSKLKKEDIYAVEIVGGATRIPAVKEKISKFFGKELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGLSDCEVFPKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPD-PAIAQFSVQKVTPQSDGSSSKVKVKVRVNVHGIFSVSSAALVEVH---KSE--ESEEPMETDQNAKEEEK-----MQVDQEEPHTEEQQQQ------PQTPAENKAESEEMETSQAGSKDKKTDQPPQAKKAKVKTSTVDLPIE-HTLWQLDREMLALYTENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSG-EYEKFVSEDDRNTFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKSLGQPIKTRFQESEERPKLFEELGKQIQQYMKVISSFKNKEDQYEHLDAADVTKVEKSTNEAMEWMNSKLNLQNKQSLTVDPVVKTKEIEAKIKELTSICSPIISKPKPKVEPP--KEEPKH-AEQNGPVDGQGDNPGSQAAEHGADTAVPSDGDKKLPEMDID", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P34932-1", "uniprot_id": "HSP74_HUMAN", "id": "P34932-1", "name": "Heat shock 70 kDa protein 4", "aln": "-MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGKELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVFSKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPD-PAIAQFSVQKVTPQSDGSSSKVKVKVRVNVHGIFSVSSASLVEVH---KSE--ENEEPMETDQNAKEEEK-----MQVDQEEPHVEEQQQ--------QTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSG-EYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPP--KEEQKN-AEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMDID", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48722-1", "uniprot_id": "HS74L_MOUSE", "id": "P48722-1", "name": "Heat shock 70 kDa protein 4L", "aln": "-MSVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNVRNTIHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSTGVKVRYLEEERPFAIEQVTGMLLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAYGIYKQDLPSLDEKPRNVVFIDMGHSAYQVSVCAFNKGKLKVLATTFDPYLGGRNFDEALVDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNRAQFEQLCASLLARVEPPLKSVMDQANLQREDINSIEIVGGATRIPAVKEQVTRFFLKDISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSVTLRWKTSFEEGTGECEVFSKNHPAPFSKVITFHKKEPFELEAFYTNLHEVPYPD-PRIGNFTIQNVFPQSDGDSSKVKVKVRINIHGIFSVASASVIEKQ---NLEGDHNDAAMETEAP-KSEGKEDVDKMQVDQEEGGHQKCHA-------EHTPEEEIDHTGAKAKAPPSDKQDRINQT--IKKGKIKS--IDLPIQSSLYRQLTQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDKLGT-VYEKFITPEDMNKLSAMLEDTENWLYEEGEDQPKQVYVDRLQELKKYGQPIQMKYVEHEERPKALNDLGKKIQLVLKVIEAHRNKDERYDHLDPAEMERVEKYISDSMNWLNSKMNAQNKLSLTQDPVVKVSEIVTKSKELDNFCNPIVYKPKPKVEAP--EDKAKTGSEHNGPMDGQSGSETSPDPPKGSSQHTDS------GEMEVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95757-1", "uniprot_id": "HS74L_HUMAN", "id": "O95757-1", "name": "Heat shock 70 kDa protein 4L", "aln": "-MSVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNVRNTIHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGMLLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAYGIYKQDLPPLDEKPRNVVFIDMGHSAYQVLVCAFNKGKLKVLATTFDPYLGGRNFDEALVDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNRAQFEQLCASLLARVEPPLKAVMEQANLQREDISSIEIVGGATRIPAVKEQITKFFLKDISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSITLRWKTSFEDGSGECEVFCKNHPAPFSKVITFHKKEPFELEAFYTNLHEVPYPD-ARIGSFTIQNVFPQSDGDSSKVKVKVRVNIHGIFSVASASVIEKQ---NLEGDHSDAPMETETSFKNENKDNMDKMQVDQEEG-HQKCHA-------EHTPEEEIDHTGAKTKSAVSDKQDRLNQT--LKKGKVKS--IDLPIQSSLCRQLGQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDRLGT-VYEKFITPEDLSKLSAVLEDTENWLYEDGEDQPKQVYVDKLQELKKYGQPIQMKYMEHEERPKALNDLGKKIQLVMKVIEAYRNKDERYDHLDPTEMEKVEKCISDAMSWLNSKMNAQNKLSLTQDPVVKVSEIVAKSKELDNFCNPIIYKPKPKAEVP--EDKPKANSEHNGPMDGQSGTETKSDSTKDSSQHTKSS-----GEMEVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9MSL3-1", "uniprot_id": "M9MSL3_DROME", "id": "M9MSL3-1", "name": "", "aln": "-MSVIGIDFGNESCYVAAARSGGIETLANDYSLRATPSFVAFDGKKRIIGVAAKNQQVTNMKNTVGGFKRLLGRKFNDPHVQHELTSIPARVEARGDGSIGIKVNYLGEDQHFGPEQLTAMLFTKLKETSAAAMQTQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYKNDL--FEDKPRNVIFVDFGHSSLQASACAFTKGKLKMLASTWD-QIGGRDIDLALGDYFAKEFQERYKINAKTNARANLRLLTEIEKLKKQMSANSTKLPLNIECFLDDIDVSSSMQRSQMEELCAPVLQRVEQTFKRLLAESKLQLDDIHSVEIVGGSSRIPSVKQLIEQVFNKPASTTLNQDEAVSRGAALQCAIMSPAVRVREFGVTDIQNYAVKVLWDSEGSAAPGEIEIFPQYHASPFSRLLTINRKGPFNVSIVYG--QQVPYPD-QTIGVWKVKDVKPTERGEGQDVKLKVRINNNGIVLISSATLVEKK--------EAEEAAAAAEQAASEEKPGDQTNNTGEPADGQQEAYCE--------NEDDNNTSTASSPGGQGWAQRVKGWFGSGADKKKKASKATELPLECTTHGFSPVDLSN-YTQQESKMIGNDQKETERIDAKNALEEFVYDMRNKLQGGPFERYVVEAEREKIVSQLNDLENWLYEDGEDCERDIYTSRLQALHQKTDPIKLRASDYEQGPAAFDELKNSIAIARLAVAEFRKGVPKYDHLTETEFINISETADKAQSWLDANLPKFTQSPRTADSPVQISAVRQEVQTLNSCVSSVINRAKPKPTPAKTATPPKDEANAEQNGGEPAANSGDKMDVDNNGQSAAGN----DPSMEVE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32589-1", "uniprot_id": "HSP7F_YEAST", "id": "P32589-1", "name": "Heat shock protein homolog SSE1", "aln": "MSTPFGLDLGNNNSVLAVARNRGIDIVVNEVSNRSTPSVVGFGPKNRYLGETGKNKQTSNIKNTVANLKRIIGLDYHHPDFEQESKHFTSKLVELDDKKTGAEVRFAGEKHVFSATQLAAMFIDKVKDTVKQDTKANITDVCIAVPPWYTEEQRYNIADAARIAGLNPVRIVNDVTAAGVSYGIFKTDLPEGEEKPRIVAFVDIGHSSYTCSIMAFKKGQLKVLGTACDKHFGGRDFDLAITEHFADEFKTKYKIDIRENPKAYNRILTAAEKLKKVLSAN-TNAPFSVESVMNDVDVSSQLSREELEELVKPLLERVTEPVTKALAQAKLSAEEVDFVEIIGGTTRIPTLKQSISEAFGKPLSTTLNQDEAIAKGAAFICAIHSPTLRVRPFKFEDIHPYSVSYSWDKQVED-EDHMEVFPAGSSFPSTKLITLNRTGDFSMAASYTDITQLPPNTPEQIANWEITGVQLPEGQDSVPVKLKLRCDPSGLHTIEEAYTIEDI--------EVEEPIPLPEDAPEDAEQ--------------------------------------------------------EFKKVTKTVKKDDLTIVAHTFG-LDAKKLNELIEKENEMLAQDKLVAETEDRKNTLEEYIYTLRGKLEE-EYAPFASDAEKTKLQGMLNKAEEWLYDEGFDSIKAKYIAKYEELASLGNIIRGRYLAKEE---------------------------------EKKQAIRSKQEASQMAAMAEKLAAQRKAEAEKKEEKKDTEGDVDMD----------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .*:*.* .. :*.** **: :.*: * *.**: :.:. :.* :* :.*.: :: .**: .:*:: * : .* .: * :. : * :* : *.: * *::.*:: *:*:* : : * :: * ::*: :* : *:::.*** :*::*: **..: **::* ** ::*** * *:*:***: **.:*:**:*.:: * :**:.:* : ::*. ** :**:: : : :* *: ***** :*:* :. *:.:*..::* ***. :.* :: :: :* :: .. : :::*. ::: :**:**::***::*: : . * * ***** ***:::*.*: *** **:.:** * . * :.:. *. . . *:* . * ::::*: : * : * :* *. : : * . . **:*:* : *: : * :* : : .* . :*.: . : *.:*: :*: * * **::** :* :*.:* : : : .: * . *:***::* * : * : * . :: : *: . .: . : : : . : . . ", "identical_positions": 160, "similar_positions": 224, "identity": "18.52%" }, { "cls_id": "homologset.agr.SGD:S000006028", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VBA6-1", "uniprot_id": "Q9VBA6_DROME", "id": "Q9VBA6-1", "name": "Oxidoreductase-like domain-containing protein", "aln": "MLAPLGFSCPRCLLLRRGAERWASLARQLSGSSSQDDASSKDAAAQEAASGCPPNSTTTGTDTPKAKDKTTKGRKRLRNIEIPPEPTTCCMSGCANCVWLDYAQTLAKLLGDNDEEAREIVLSKITDPN---------LKMFLSLELRQMAKQREEKAAAEKAAKQGK----PKKSSPPP-----------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02873-1", "uniprot_id": "YP107_YEAST", "id": "Q02873-1", "name": "UPF0651 protein YPL107W, mitochondrial", "aln": "MIRNQGWSLLYRIYPVRRFTRYSRVDMTFEG-NTQDISTSVEERMTTVFGGRLKGEPPR--STSRVLSGGTKKIAGVQVPAKPQEPDNCCMSGCVNCVWEIYSEDLRDWKHRRKEAAEKIAGTKEKWPKDWNPPLGLLHMENVPVELREKKLETDSKKAEQPHDLSAIRSLFPKRKGPLPKSVLAAKRKNIALRHNYEQKDGGDQSVSESDADEGWEDIPVYVKAFAEFESKKRLQKIRRQEEIKKRTALV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *:* : * *:: : :.* .:** ::* : . .* .... .*.:. . ** :: * ** .******.**** *:: * . ..* *.:*. :* . *: :.:***: : :.* * : .. **:..* * ", "identical_positions": 42, "similar_positions": 52, "identity": "16.73%" }, { "cls_id": "homologset.agr.SGD:S000006030", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NSR3-1", "uniprot_id": "ADCK2_MOUSE", "id": "Q6NSR3-1", "name": "Uncharacterized aarF domain-containing protein kinase 2", "aln": "-------MVTPWRLSVRVCLSHLRCFEFRKELG------HSRPLGCSRNARLCWFLLGTLPKLISAHGSVGEGAPGSLCQRKTHWSDLAENGLVEKVAQEG------PLARVLLCLRLGLRAGVLLAKFFPLLFLYPLTYLAPGLST------------LWLHLLFKATETSGPTYIKLGQWASTRRDLFSEAFCTQFSKLHVQVTPHPWARTEYLLQQAFGEDWGSLLFFET-REPVGSGCVAQVYKAFASISLLEEDRIWRLGELSAPG----TRAVVMQREPF---MKDRKPSENLADEAFLEKLLLPKADLGGSEVGVS--QAPWHLPKSDHLIPVAVKVLHPGLLSQVSMDLLLMKIGSKALGLLPGVKWLSLPEIVEEFEKLMVQQTDLRYEAQNLEHFQHNFQDMASVKFPTPLRPLITRDILVETYEESVPVSSYQQAG---IPTDLKRKIAQLGINMLLKMIFVDNFVHGDLHPGNILVQGADG-------VSPSLEMQQQQVNVCDTLVATIAP----------ALCPLRLVLLDAGIVAKLQASDLRNFRAVFQAVVMGQGHRVAELMLHHAQ-ANECRDVERFKAEMATLVTQARKNIVTLEKLHVSSLLSSVFKLLMTHKVKLESNFASIVVAIMVLEGLGRSLDPTLDILEAAKPFLFKG-----PASFL-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZRE6-1", "uniprot_id": "D3ZRE6_RAT", "id": "D3ZRE6-1", "name": "", "aln": "-------MVNPWRLSVRVCLSHLRCFEFGKELG------LSRPLGCSRNARLCWFLLGALPKFISAQGSVGEAAPGSLCQRKTHWSNLPENGLVK-VAQEG------PLARILLCLCLGLRAGVLLAKFLPLLFLYPLTYLAPGFST------------LWLHLLFKATETSGPTYIKLGQWASTRRDLFSEAFCVQFSKLHVQVTPHPWARTEYLLQQAFGEDWHSILFFET-QEPVGSGCVAQVYKAFANISLLEKGRIWRLGELSVPG----TGTVGTQRDPF---MKDWRPSENLADETFIEKLLLPKADLVRSEVGVS--QAPGQPPKSDHLIPVAVKVLHPGLLSQVYIDLLLMKIGSQALGLIPGVKWLSLPEIVEEFEKLMVQQTDLRYEAQNLEHFQHNFQNMASVKFPTPLHPLITRDILVETYEESVPVSSYQQAG---VPTDLKRKIAQLGINMLFKMIFVDNFVHGDLHPGNILVQGADG-------VSSSLEMQQQQVDVYDTLVATIAP----------ALCPLRLVLLDAGIVAKLQASDLRNFRAVFLAVAMGQGHRVAELMLHHAQ-ANECKDVEKFKAEMATLVTQARKNTLTLEKLHVSSLLSSVFKLLMTHKVKLESNFASIVVAIMVLEGLGRSLDPKLDILEAAKPFLLKG-----PASFL-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z695-1", "uniprot_id": "ADCK2_HUMAN", "id": "Q7Z695-1", "name": "Uncharacterized aarF domain-containing protein kinase 2", "aln": "-------MVAPWRVSVRVCLSHLRCFELRQGLS------LLRPSECPRDARLCWLLLGTLPKVVSLCGDVGEGAPDVLSRRRVRCSGAAGAGPAESLPRAG------PLGGVFLHLRLWLRAGALLVKFFPLLLLYPLTYLAPSVST------------LWLHLLLKATETSGPTYIKLGQWASTRRDLFSEAFCAQFSKLHVRVTPHPWTHTERFLRQAFGDDWGSILSFEN-REPVGSGCVAQVYKAYANTAFLETDSVQRLGRASCLPPFSHTGAVGGLRELFGYLGNGRKPPENLADQSFLERLLLPKADLVGSNAGVSRAQVPGHQPEATNLISVAVKVLHPGLLAQVHMDLLLMKIGSRVLGVLPGIKWLSLPEIVEEFEKLMVQQIDLRYEAQNLEHFQVNFRNVKAVKFPTPLRPFVTREVLVETYEESVPVSSYQQAG---IPVDLKRKIARLGINMLLKMIFVDNFVHADLHPGNILVQGANG-------LSSSQEAQLQQADICDTLVVAVPS----------SLCPLRLVLLDAGIVAELQAPDLRNFRAVFMAVVMGQGQRVAELILHHAR-ASECRDVEGFKTEMAMLVTQARKNTITLEKLHVSSLLSSVFKLLMTHKVKLESNFASIVFAIMVLEGLGRSLDPKLDILEAARPFLLTG-----PVCPP-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PXA8-1", "uniprot_id": "A0A8M9PXA8_DANRE", "id": "A0A8M9PXA8-1", "name": "", "aln": "----------MSVFCTRHLLHSFKCFARRLPIPT-----QSRRVFFVKATRLLSQTPKVGLFCWTACGTIYAAGPESLKN--------HQNPTERKSVAGV------QIHRLVFVLRLGLRALVLLLKFSPLLLLYPLTLLSQRWAS------------HWLDCLLWVTETSGPTFIKLGQWASTRRDIFSQDFCDRFSRLHVRVKAHSWSHTKLCLKRAFGEGWRQMFVFDS-KEPVGSGCVAQVYRAKAKVANIQDPAFQKLLEELEKK------NLLEAWEIP-------GLGGALSDFWEINRDEDEMTDGKMKEFGER--SGQGEHLEEERLIPVAIKVLHPGIRQQVQIDLILMKAGSLFLNCLPGVKWLSLPEIVEEFQKLMTKQIDLRFEAQNIEKFQKNFKDLEYVKFPTPLRPFVTRTVLVETYEESEPISKYLSSN---IPAGVKQRIARMGVDLLLKMVFVDNFVHGDLHPGNILVQGSCG-------EES--EDRATLTDLWDTVVVSMRA----------TPPSLQLVLLDAGIVAQLSEADQRNFRAVFTAVVLRQGERVAELILHHAR-ANECQDVMRFKKEMAELVDRALSDTLSLGKIQVAELLSQVFGLLIHHKVKLESNFASMVFAIMVLEGLGRSLDPNLDILEMAKPLLLKN-----CTSLL-----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02981-1", "uniprot_id": "YP109_YEAST", "id": "Q02981-1", "name": "ABC1 family protein YPL109C, mitochondrial", "aln": "MSFLKFAYRNSWRYYSKSTRHFHKIPIRQFIIPTSIAFYLTQNSFPKQNCLIYNDSLKPDPKGDTFEMGLYVSSENELQEKLKSFRSAKITESRNKLIRYLRIFWFGFNDNIVEPVCTILRFLEISAIFLPLLLLYPISWFGHKLKITDTNITETRGSLIWCQLLRKALELAGPSFIKLGQWAGSRTDIFSHALCHELGKLHSNVTAHSLSFTLEKLSQALKVDKIEDAFDEFNRTPIGVGSIAQVYVGELSQKYIDKYDNIQIGKDGNRW--------------------------------------------------------------------CAIKILHPNVRSQIRRDLKIMKFCADAINWIPTMEWLSLPSEVDQFSILMNIQLDLRIEALNLERFNENFKNSIQVKFPKPFLPLSNRDVMFEEHVYGLSMEKFLSTKKQINDVELCKKVSDPFVDAFLQMLILDDFVHADLHPGNVIIRFVKTNKYGTNIISSELESYRITHDLRKKIEEDQDQDFVGKLKSVLTNYTPQICFIDTGIITELNEKNRINFIALFNALARFDGYRAGELMIERSRTPETAIDKEVFAFKVEKLVDKVKQRTFTLGTVSIGDLLDQMLSMVRSHHVRMESDFVSVVVAILLLEGIGRQLDPNLDLFESSLPILREFGFKREAKSLLKDASTLSMLKIWVGLEVRQLMHLSMKQIYDLVRTDQLCPNY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : : : : : .. * . . :. : ** : * ***:***:: :. * . * . * :**::*******.:* *:**. :* .:.:** .*..*. : * * :*: . . : : *:* *.:**** . . :: :: . *:*:***.: *: ** :** : :. :* ::*****. *::*. ** * *** ** *:*:*: **:: ****.*: *: .* ::.* : . .:..: .: . : :::: :: :::*:::*:***.******:::: .. * :: ..: : . :: ::*:**:::*. : ** *:* *:. :* *..**::.::: .. . * * :: ** :. . .:* .: :..**..:: :: *:*::**:*.*:*.**::***:**.***.**::* : *:* . ", "identical_positions": 134, "similar_positions": 182, "identity": "18.48%" }, { "cls_id": "homologset.agr.SGD:S000006031", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80VJ4-1", "uniprot_id": "GPCP1_RAT", "id": "Q80VJ4-1", "name": "Glycerophosphocholine phosphodiesterase GPCPD1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTPSQVTFEIRGTLLPGEVFAMCGNCDALGNWSPQNAVPLT-ESETGES----VWKAVIVLSRGMSVKYRYFRGCFLEPKTIGGPCQVIVHKWETHLQPRSITPLENE---------------------------------------------------------------IIIDDGQFGIHN-------------------------------------------------------------------------------------------------------------------------GVET-----LDSGWLT-CQTEIRLRLHFSEKPPVSITKKKFKKSRFRVKLTLEGLEED-DDDDDKASPTVLHKMSN-------------------------------------SLEISLISDNEFKCRHSQPECGYGLQPDRWT-----EYSIQTMEPDNLELIFDFFEEDLSEHVVQGDVLPGHVGTACLLSSTIAESERSA---------------------------GILTLPIMSRSSR-KTIGKVRVDFIIIKP-LPGYSCSMQSSFSKYWKPR-IPLDVGHRGAGN-STTTAKLAKVQENTIASLRNAASHGAAFVEFDVHLSKDLVPVVYHDLTCCLTMK----------------------------------RKYEADPVELFEIPVKELTFDQLQLLKLSHVTALKTKDQKQCMAEEENSF----------------SENQPFPSLKMVLES--LPENVGFNIEIKWICQHRDGVWDG-NLSTYFDMNAFLDIILKTVLENSGKRRIVFSSFDADICTMVRQKQNKYPILFLTQGKSDIYPELMDLRSRTTPIAMSFAQFENILGINAHTEDLLR--NPSYVQEAKDKGLVIFCWGDDTNDPENRRKLKEFGVNGLIYDRIYDWMPEQPNIFQVEQLERLKRELPELKNCLCPTVSHFIPPSFCMESKIHVDANGIDNVENA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C0L9-1", "uniprot_id": "GPCP1_MOUSE", "id": "Q8C0L9-1", "name": "Glycerophosphocholine phosphodiesterase GPCPD1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTPSQVTFEIRGTLLPGEVFAICGSCDALGNWNPQNAVALINENETGDSV---LWKAVIALNRGVSVKYRYFRGCFLEPKTIGGPCQVIVHKWETHLQPRSITPLESE---------------------------------------------------------------IIIDDGQFGIHN-------------------------------------------------------------------------------------------------------------------------GVET-----LDSGWLT-CQTEIRLRLHFSEKPPVSISKKKFKKSRFRVKLTLEGLEEDEDDDDDKVSPTVLHKMSN-------------------------------------SLEISLISDNEFKCRHSQPECGYGLQPDRWT-----EYSIQTMEPDNLELIFDFFEEDLSEHVVQGDVLPGHVGTACLLSSTIAESGRSA---------------------------GILTLPIMSRNSR-KTIGKVRVDFIIIKP-LPGYSCSMQSSFSKYWKPR-IPLDVGHRGAGN-STTTAKLAKVQENTIASLRNAASHGAAFVEFDVHLSKDFVPVVYHDLTCCLTMK----------------------------------RKYEADPVELFEIPVKELTFDQLQLLKLSHVTALKTKDRKQSLYEEENFF----------------SENQPFPSLKMVLES--LPENVGFNIEIKWICQHRDGVWDG-NLSTYFDMNVFLDIILKTVLENSGKRRIVFSSFDADICTMVRQKQNKYPILFLTQGKSDIYPELMDLRSRTTPIAMSFAQFENILGINAHTEDLLR--NPSYVQEAKAKGLVIFCWGDDTNDPENRRKLKEFGVNGLIYDRIYDWMPEQPNIFQVEQLERLKQELPELKNCLCPTVSHFIPSSFCVEPDIHVDANGIDSVENA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPB8-1", "uniprot_id": "GPCP1_HUMAN", "id": "Q9NPB8-1", "name": "Glycerophosphocholine phosphodiesterase GPCPD1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTPSQVAFEIRGTLLPGEVFAICGSCDALGNWNPQNAVALLPENDTGESM---LWKATIVLSRGVSVQYRYFKGYFLEPKTIGGPCQVIVHKWETHLQPRSITPLESE---------------------------------------------------------------IIIDDGQFGIHN-------------------------------------------------------------------------------------------------------------------------GVET-----LDSGWLT-CQTEIRLRLHYSEKPPVSITKKKLKKSRFRVKLTLEGLEED---DDDRVSPTVLHKMSN-------------------------------------SLEISLISDNEFKCRHSQPECGYGLQPDRWT-----EYSIQTMEPDNLELIFDFFEEDLSEHVVQGDALPGHVGTACLLSSTIAESGKSA---------------------------GILTLPIMSRNSR-KTIGKVRVDYIIIKP-LPGYSCDMKSSFSKYWKPR-IPLDVGHRGAGN-STTTAQLAKVQENTIASLRNAASHGAAFVEFDVHLSKDFVPVVYHDLTCCLTMK----------------------------------KKFDADPVELFEIPVKELTFDQLQLLKLTHVTALKSKDRKESVVQEENSF----------------SENQPFPSLKMVLES--LPEDVGFNIEIKWICQQRDGMWDG-NLSTYFDMNLFLDIILKTVLENSGKRRIVFSSFDADICTMVRQKQNKYPILFLTQGKSEIYPELMDLRSRTTPIAMSFAQFENLLGINVHTEDLLR--NPSYIQEAKAKGLVIFCWGDDTNDPENRRKLKELGVNGLIYDRIYDWMPEQPNIFQVEQLERLKQELPELKSCLCPTVSRFVPSSLCGESDIHVDANGIDNVENA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LVM1-1", "uniprot_id": "Q1LVM1_DANRE", "id": "Q1LVM1-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSTKVTLTVRGSTALGEVIAVVGSCETLGSWCQQKAVTLQPAEEDGTL-----WRTTIHVPRGAETKYRYFKAFILESKNAGGPCQVIVNRWETHQLPRSLSPSEPE---------------------------------------------------------------LVVDDGHFGVHD-------------------------------------------------------------------------------------------------------------------------GAEC-----VDSGWLT-CQTEIRLRLHYSVKPPVSITKKKFKTSRFRLKLMLEGVEEE---EEEEESPSSWHKMTT-------------------------------------TLEMSMISDDGYKSRHSQPECGYALEPSRWT-----EYTIHTMDPDNLVLTFEFFEEDLSETVVQGDAHPGHVGTACLLSSSFVESGKDL---------------------------GVVTLPIMSRNSR-QTLGKVRVDYLVTRP-IQGLQCDMSRSFTKYWRKR-SALDVGHRGAG--STHAAKHHKIRENTIASFLSAANHGAAYVEFDVHLSKDLVPVVYHDLTCCISTK----------------------------------KKNDKTSMLLFEVPVKDLTFDQLQLLKLAHTTALDTHDHKD-LQDEEEYI----------------DEHQPFPSLPQIFQS--VPENVGFNIELKWISQFKDGSWDA-NLSTYFNMNQFLDIILTCVLQNAGNRRIIFSCFDPDVCTMVRQKQNKYPILFLTQGVTQLYPELMDIRCQSTKIAMSFAQSENILGISAHTDELLK--NMEFIGEAQSKGLVVFCWGDYNNDHENRRKLREHGIDGLIYDRICEDKLEQSNIFKMEEQGGNLKEV--IQTCACSTYSIPCSSFPCPGRPSETNGESDSGLSSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVV4-1", "uniprot_id": "Q9VVV4_DROME", "id": "Q9VVV4-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYRSRVCLNVLKSISIPHGLLVLQLLLLLLPLCGAFVN-----------------------ETTVFGPEKLQAFKIFDD---------EQPGQISGRSFICVPLFRIFSLELRHNIRLAPDEFVAVSGDHPALGLWQLEKALPLKEQD-----KARTKWYLRVWICASQRFYYRYLIYSKN------RQGNRVLRTWEGQRVARMLQTYEIY---------------------------------------------------------------RSPGLDIFGEAY-------------------------------------------------------------------------------------------------------------------------PVSVGGGFYLERGWLQ-YEYVIELKFVWQ------------DHIAISGMG-------SNAKYRLILTPLNLIDD-----------------------------------------TRIEVSRYAYNQSSFRPQNQRGVRYTQGT-----IVVFRIYQPLDTYNALRLSIYQAS------RDLQLSLGEAYIFPDQIKGSR------------------------------GILQLPIFASLQN-LAIGEITLPYLVVQPMPKVEAGNLRASFHHYWPDNWPTLDVGYRGLG--ASYFQSSTSLTENTIESYLAVLKAKGDMVQLDVQLTKDYVPVVWHGFGFYTSDT----------------------------------DRSVRDRFDLRFVLIRELTYSELKASRVFILKRWTVQEYTNLNVKDVS------------------QKHRIFPKLSEVFEA--LPKTLGLLVEIKWPQIMASGVPES---TQSLNKNIYVDRILQITIHHGCGRPLIFASFDADICTMIRLKQHVFPVILMSIGKSQIWDEYMDLRAQSFQQAINFVQSAEILGTALHVENFQ--NKHQQVNLALDLQQSLFLWGNDMQDEHLLEQFRALDVTGLIYDHMDRVGPFAWKRSEFFRAP--QLMELFGAQCVSSGNSTTIPGIKPAKPTIWPKLR--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q86BI9-1", "uniprot_id": "Q86BI9_DROME", "id": "Q86BI9-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------MIFSRAPVQHVILFAPLKVTSGSGATKDACLSRELVFDSKSRNRRFRRAGGGIGSTGARELGSRDSRQSTPRLEKLYQAETESARGHRLISLAQQESCRAFNSGLRRSIDFQSARDLHSNPMAMSRTVLILAVALSLQCAAFVDGASITYGTGNELESGSGSSAACKPTLREFN--VRLEVPLAAEERLGLTGDVKALGEWQLSRSVALESLD-----ELN--WQATVALQSCRQLEYRYFVYVED------LSGYKQIRRWETHFKPRSLGPCTEL---------------------------------------------------------------QCSQLDVFGITS-------------------------------------------------------------------------------------------------------------------------DNSD-LKPQVHRGWLN-HEAILQLKFNGE------------KMFQVHDIETF-----DPQHVQLKIVPVEKTAG-----------------------------------------LHVEYSKQEYGKSQLELQPTFGVPYTKGD-----IVIFHITLPLERMMEQHFRLECYS------MSNEL-LGSATLVTSDLTGSE------------------------------GVLHLPIKSAKNADETLARLRLPYVAVQPY-RYSPLDFKNTYAHYWPKSWPNLDVGHRGNG--KSYIADAPAERENTIASFLSAHEHHADMIELDVHLTADGVPVIYHDFGLRTAPP----------------------------------GKQISRPDQLEYVLIKDINYELLKRLRIFSVIAGQVREYPSHNAEPR-------------------MEHRIFPTLVEVLEK--LPKSLGIDVEIKWPQRRQGGGSEA---EQTIDKNFFADKVIHQVIQKGCGRPIIFSSFDADMCTMLRFKQNVFPVMFLTQGETKKWQPFLDLRTRTFIAAVNNAQAFELAGTAPHAEDFLGENASEMLRKAKDLGQIAVIWGDDCNSKERVQYFTRIGATATCYDRSDLFMP-EGKREAFFKSP--ALMAEFAAQCRI------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQU3-1", "uniprot_id": "Q9VQU3_DROME", "id": "Q9VQU3-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHNWLASHNGDED---------------------------------AMAAPSSCPASSE---------NGSRLESRRIFGDITTNRLWTFRVLMNQDLAPNEQLAIVGNCEALGNWQHSGAAILSKNEEDNEYS--NLWTGEIYIPRHCDTEYRYMVCAVDP-----GTEQLIVRRWETQLQPRIVKELDEQP--------------------------------------------------------------AKNQSDIFGSFN-------------------------------------------------------------------------------------------------------------------------GQE-----KVDRGWLT-KETLVQLKFFYAPFTFKQRMKRRHIQVKVTPMNLS--IPSAGCDTMLPSSPMEDSLSNDTHDTKENGGESST------------------------AFAFSEVVTLSADECEIRSQEQFGTGCGPTD-----LVIFHLTVGDFENTAYLIDLYSYSSRVAKEDGPPNHLGYHYVLPNLFKRSE------------------------------GNLELPITCAKGH-RPLGMMRLGYLIVKPSSLCALMDMSVSYARYWNSKWTGLDVGHRGSG--TSFKAKDAVIRENTITSLKNAAEHGADMVEFDVQLSKDLVPVVYHDFMIYVSLK----------------------------------SKCSLQEHDFLALPMRELSLEQLKKLKVYHIAEGLSRETRSF-HNDDC------------------LEHQPFPQLCDVLD--ALDVHVGFNIEIKWSQRLEDGKMEE-EFEHVVDRNLYIDCILDVILRKAGNRRIVLSCFDPDICTILRFKQNRYPVMFLTLGRTTKYQKYMDPRGNSMELAVWHAVAMEFLGVVAHTEDLLR--DPSQVNLAKERGLVLFCWGDDNNSKDTIKLLKELGLHAIIYDKMDVLTTKEVKQSVFHLQAKDSQKELLKLQALEMGHVWHTSADGNEEQQA-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGB2-1", "uniprot_id": "Q9VGB2_DROME", "id": "Q9VGB2-1", "name": "Glycerophosphocholine phosphodiesterase GPCPD1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHRWFFANEREEC---------------------------------ERKPEEDGPSSAS---------ETQEPPPP----PPVPTTEWPFCVVFHSSLNGNEYVAISGNCPSLGNWDPKEVYILAKNDCISCLCNCRQFEASLEIPRNIDIHYRYCVVIHDP-----ETDEVYIRFWESQLYPRVIRTCQN----------------------------------------------------------------MLKNCDVFGKPH-------------------------------------------------------------------------------------------------------------------------DDDE--ANQVDRGWAT-TETIVHLKIFNAPFCWQR-QKPRLLYVHVQPMFEVPENPCNEPANPIKMVSSQTRLSRYLSTREIKAGNQYL------------------------QLAQVEVTNLCVQN-ALAAQQRFGARCGPKD-----MELFHCSIAFPEETLYRLDLYTYAHKAGYDE-PPYHYGYGFLMPDQLLGTE------------------------------GSARVKITCASTH-RPLMEMCVRYLIIRP-LPNFRCDLSHSYERYWRKNRLCMNIGHKGSG--NTYRLGSDVVRENTLYGFKQAVLANADMVEMDVQLTQDAQVVVYHDFVLRFMLQRMPSFEDLLENQDLLIFAYENLNKL------MLLAMGGSKRKDLIAVPLEAFSYDQLKEVKVLRFAG--SKGCDKS-CDRML------------------LEQRPFPLLLDLLDEENLPVDMGFLIEIKWPQMTNMRRWESGSFKPTFDRNFYVDTILEIVLNKAGKRRIVFCSFDADICAMVRFKQNVYPVTLLLEDPHSP-VQYADQRVSVQDVAVRFCNSLEFLGLTLHANSLLN--KPSTMAYLHQINLDAFVYGSSTIDLEIRNKLKKHGVLGIIYDRLDQLDQVGEELEGDTMCTIDSVTTRRVIQETEVEEWIQKCGYKPETSIVVHNIYID------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2L6-1", "uniprot_id": "Q9W2L6_DROME", "id": "Q9W2L6-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVSWSKTFAAFT----------------------------------VAWLSALCLLPVETFCDTSYYEKYYAARRYVPLKRNAPLVFNFTLTLPDADQLASFERPALVGNLPVLGAWQAGRAVLLNRTAILN------VWSASVEIPQNSSVEYRYFAAAVGQ------SGAVQIRRWESHVQARTFNTTKFS----------------------------------------------------------------GNRSDEFGLIG-------------------------------------------------------------------------------------------------------------------------NERQ-----LSRGWLQDSGNILQLKLFREALSLEEQPEVGQEKLRLRLQP----------VDPKTLAPILSSARAN-----------------------------------------VEYVRMAYGDSKLRVQPEYGVPYATGD-----ILMFHVNLEQLDRVAYLVEVYAEQP----DEDLVRLLGYSHLLHTSFSGTE------------------------------GDVSIDLISPLWQ-RVVGQLRIEYLHIRP-MEKDGFDLRTSFANYWRSNWTALEIGHRGLGKSLTVTTNAAPLIENTVATMLASSELGADLVEFDVQLTSDLVPIIHHDFSIRVCID----------------------------------SKTPTSKDDLTEVLLKDISYEQLKDLKTYQIVGNKIVEYPAHNNVEPP-------------------EQRLFPTLQDFFER--VNLSTGFDIEIKWPQQRADGLFES---EQTLDKNLFADRILAVVRRHGCGRLNVIKSFDADLCSLLRFKQHMYPVLFLS---SSKENVFNDPRTSTVEQSVNFAQAFDLGGVSPNAVFVKA--DPGLVQRAKAQVPIVLLWGSDLKDRESIDWFLQQGPTGVIYDRLDLWLGANRTSAFEAEQDLPGYFQLQCDPAPKEREVNSTIESILSNVNFL------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02979-1", "uniprot_id": "GDE1_YEAST", "id": "Q02979-1", "name": "Glycerophosphocholine phosphodiesterase GDE1", "aln": "MKFGKTFANHRIPEWSSQYVGYKSLKKMIKEITRLQEDIYRAHNKNSYDEGRPPTKMRDSSNSAQNYLDSPKIQKLLASFFFAVDRDIEKVDTFYNSQYAEYKKRFERLLSSNQFNEIKSTLVVDANKEDAVAQTLLTKDTREMNMLLKGTSQASRLSYHKDDLIEIQSILAELRKQFRNLKWYAELNKRAFGKILKKLDKKVGTNQQMSTMKTRILPLQFANDSLITKDLSLLKTIWEQVTFRINSYERVMRSTSPNANANDNTEFFKIICVFIEEDDSKGLIRELTNLYSELSLIPTRIMISVLNKAALSKSLACIDAILKVIPSLNDSEDINRRNFFHHHIIAIGKLIRKQEILSRKKKSQPSKYTNSEGEIVTDLRTLHTTLSAPAESDSITEEEKSSACTLSYILEELPIHLRPCLFQHDNYKRTPLHYSCQYGLSEVTKLIIKLMKEWNIWNEIPIDDVSAFGDAESLTPLHLCVLGAHPKTTEVLLQSLDPNVKLKSSSLLHLATEWNNYPLLHVLLSSKRFDINYQDNELHETPLYLACRLNFFEAAVCLLYNGADLEIREKLFGWTAIFVAAAEGFTDIVKLLIANNANFDIEDEGGWTPMEHAVLRGHLHIADMVQIRDELVTHPHSQLNSGSEEKEPLNEISAGELNERNENGNGGNKGSLGKLAGPIKSYGHRFLDNNESLILITLGSNDTRNKSPSISLSSEALAKVIGLETDCALSLVISCNDSIDKSSVILDLPLDDNVDAVDFKVPFKVDYSHTLYFDIVPTYGTRSLETHNRIDCQKNNNNYVMARGVSMLNKSYSSVGVNRSILNGSVTVPIIANHTL-EILGTLKFEYIIITP-FEHPQLPLER-TETYWKSLVSTRVIGHRGLGK--NNPNKSLQIGENTVESFIMAASLGASYVEFDVQLTKDNVPVVYHDFLVAETGVDIPMHELTLEQFLDLNNADKEHIQRGAGHSPHHVNGADTALQKYRGRSVDDSDVSTLRRAWDLHDNDPNGKSNNAHWSDNRMRLTKTFKKNNFKGNARGHSIASSFVTLKELFKK--IPANVGFNIECKFPMLDEAEEEELG--QIMMEMNHWVDTVLKVVFDNANGRDIIFSSFHPDICIMLSLKQPVIPILFLTEGGSEQ---MADLRASSLQNGIRFAKKWNLLGIVSAAAPILK--APRLVQVVKSNGLVCVTYGVDNNDPENASIQIEAGVDAVIVDSVLAIRRGLTKKNEK------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .: . :. : * :. . . . ** ** :. :: . : . : * : * : : . : : . :: * : ** :*::* * . ***: . :::**:*: * :: *.: : . *: * * .:. : *: :* *: : .: * : * :: :. * :: .*..*:* :: ** *: :: * * .: :: * . . : . :* . . . . * ", "identical_positions": 41, "similar_positions": 88, "identity": "3.19%" }, { "cls_id": "homologset.agr.SGD:S000006032", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07824-1", "uniprot_id": "ARGI1_RAT", "id": "P07824-1", "name": "Arginase-1", "aln": "------------------------MSSKPKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVR---DHGDLAFV---DVPNDSPFQ-------IVKNPRS--VGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPG-FSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRK--KRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGTKREGNHKPETDYLKPPK------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61176-1", "uniprot_id": "ARGI1_MOUSE", "id": "Q61176-1", "name": "Arginase-1", "aln": "------------------------MSSKPKSLEIIGAPFSKGQPRGGVEKGPAALRKAGLLEKLKETEYDVR---DHGDLAFV---DVPNDSSFQ-------IVKNPRS--VGKANEELAGVVAEVQKNGRVSVVLGGDHSLAVGSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVSFLLKELKGKFPDVPG-FSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRK--KRPIHLSFDVDGLDPAFTPATGTPVLGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTAEEVKSTVNTAVALTLACFGTQREGNHKPGTDYLKPPK------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05089-1", "uniprot_id": "ARGI1_HUMAN", "id": "P05089-1", "name": "Arginase-1", "aln": "------------------------MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVK---DYGDLPFA---DIPNDSPFQ-------IVKNPRS--VGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPG-FSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRK--KRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKP-IDYLNPPK------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O08691-1", "uniprot_id": "ARGI2_MOUSE", "id": "O08691-1", "name": "Arginase-2, mitochondrial", "aln": "------MFLRSSASRLLHGQIPCVLTRSVHSVAIVGAPFSRGQKKLGVEYGPAAIREAGLLKRLSRLGCHLK---DFGDLSFT---NVPQDDPYNN------LVVYPRS--VGLANQELAEVVSRAVSGGYSCVTMGGDHSLAIGTIIGHARHRPDLCVIWVDAHADINTPLTTVSGNIHGQPLSFLIKELQDKVPQLPG-FSWIKPCLSPPNIVYIGLRDVEPPEHFILKNYDIQYFSMREIDRLGIQKVMEQTFDRLIGKR--QRPIHLSFDIDAFDPKLAPATGTPVVGGLTYREGVYITEEIHNTGLLSALDLVEVNPHLATSEEEAKATARLAVDVIASSFGQTREGGHIVYDHLPTPSSPHESENEECVRI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08701-1", "uniprot_id": "ARGI2_RAT", "id": "O08701-1", "name": "Arginase-2, mitochondrial", "aln": "------MFLRSSVSRLLHGQIPCALTRSVHSVAVVGAPFSRGQKKKGVEYGPAAIREAGLLKRLSMLGCHIK---DFGDLSFT---NVPKDDPYNN------LVVYPRS--VGIANQELAEVVSRAVSGGYSCVTLGGDHSLAIGTISGHARHHPDLCVIWVDAHADINTPLTTVSGNIHGQPLSFLIRELQDKVPQLPG-FSWIKPCLSPPNLVYIGLRDVEPAEHFILKSFDIQYFSMRDIDRLGIQKVMEQTFDRLIGKR--KRPIHLSFDIDAFDPKLAPATGTPVVGGLTYREGLYITEEIHSTGLLSALDLVEVNPHLATSEEEAKATASLAVDVIASSFGQTREGGHIAYDHLPTPSSPHESEKEECVRI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P78540-1", "uniprot_id": "ARGI2_HUMAN", "id": "P78540-1", "name": "Arginase-2, mitochondrial", "aln": "------MSLRGSLSRLLQTRVHSILKKSVHSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSSLGCHLK---DFGDLSFT---PVPKDDLYNN------LIVNPRS--VGLANQELAEVVSRAVSDGYSCVTLGGDHSLAIGTISGHARHCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPG-FSWIKPCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIGKR--QRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQLATSEEEAKTTANLAVDVIASSFGQTREGGHIVYDQLPTPSSPDESENQARVRI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00812-1", "uniprot_id": "ARGI_YEAST", "id": "P00812-1", "name": "Arginase", "aln": "-----------------METGPHYNYYKNRELSIVLAPFSGGQGKLGVEKGPKYMLKHGLQTSIEDLGWSTELEPSMDEAQFVGKLKMEKDSTTGGSSVMIDGVKAKRADLVGEATKLVYNSVSKVVQANRFPLTLGGDHSIAIGTVSAVLDKYPDAGLLWIDAHADINTIESTPSGNLHGCPVSFLMG-LNKDVPHCPESLKWVPGNLSPKKIAYIGLRDVDAGEKKILKDLGIAAFSMYHVDKYGINAVIEMAMKAVHPETNGEGPIMCSYDVDGVDPLYIPATGTPVRGGLTLREGLFLVERLAESGNLIALDVVECNPDLAIHDIHVSNTISAGCAIARCALGETLL--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "O76895-1", "uniprot_id": "O76895_DROME", "id": "O76895-1", "name": "Arginase", "aln": "MWWSRKFASRSLRLHRLKSTGSTAPREPEQSLGIIGVPFAKGQAKQGVELAPDLLRQSSLRQVLQSSHDGLVIR-DYGNLQYAVDEPLLQQQRVHY-----HHIRNYAD--FMACNRALIEQVKLMLVENTQFLAIGGDHAIGFGSVAGHLQHTPNLSLVWIDAHADINLHSTSQSGNIHGMPVSFLLEQLRNTWQHAGL-QEIAPNCLPKDQLVYIGLRDIDPYEAFILNKVGIRYYAMDTIDRVGVPKIIEMTLDALNPQN----KIHVSFDIDALDSNVAPSTGTAVRGGLTLREGISIVEALRDTKRVQGVDLVEINPKLGS-ERDVRTTVESGLEILKSMFGYRRSGRWSNIDTGILGSD------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: .**: ** : *** .* : : .* :. . .: :. : ::. : . ... : * . :.:****::..*:: . *: ::*:***:*** :: ***:** *::**: *. . . :. .:.******::. * *:: .* ::* :*: *: ::* ::. : . * *:*:*..*. *:***.* ***: ***: :.* : .: : .:*::* ** *. .. * . : . :* ", "identical_positions": 69, "similar_positions": 102, "identity": "18.3%" }, { "cls_id": "homologset.agr.SGD:S000006038", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LRA8-1", "uniprot_id": "A0ABK0LRA8_RAT", "id": "A0ABK0LRA8-1", "name": "isopentenyl-diphosphate Delta-isomerase", "aln": "-----------------------------------------------------MSDVTVDWIDKHQLERLDEMMIVVDENDKVIGADTKRNCHQNK-NIEKGLLHRAFSVALFNSEKKVLIQRRADTKLTFPGYYTDSCCSHPLSNPEEMEEK-----DALGVKKAALRRLQAELGIPQDQVPMS-DIVFMKRYHYKAKSDAVWGEHEVCYLLLIKK----DVKICPDPSEVSSFSYLTREELEELLERGARGEVQVTPWLRFVVEQFLYAWWPYLDEATRFIELDKIYRV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LVT8-1", "uniprot_id": "A0ABK0LVT8_RAT", "id": "A0ABK0LVT8-1", "name": "isopentenyl-diphosphate Delta-isomerase", "aln": "-----------------------------------------------------MSDVTVDWIDKHQLERLDEMMIVVDENDKVIGADTERNCHQNK-NIEKGLLHRAFSVALFNSEKKVLIQRRADTKLTFPGYYTDSCCSHPLSNPEEMEEK-----DALGVKKAALRRLQAELGIPQDQVPMS-DIVFMKRYHYKAKSDAVWGEHEVCYLLLIKK----DVKICPDPSEVSSFSYLTREELEELLERGARGEVQVTPWLRFVVEQFLYAWWPYLDEATRFIELDKIYRV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LJQ1-1", "uniprot_id": "A0ABK0LJQ1_RAT", "id": "A0ABK0LJQ1-1", "name": "isopentenyl-diphosphate Delta-isomerase", "aln": "-----------------------------------------------------MADVTVDWIDKHQLERLDEMMIVVDENDKVIGADTKRNCHQNK-NIEKGLLHRAFSVALFNSEKKVLIQRRADTKLTFPGYFSDSCSSHPLSNPEEMEEK-----DALGVKRAALRRLQAELGIAQEQV----DIVFMTRYHYKAKSDAVWGEHEVCYLLLIKK----DVKICADPSEVSSFSYLTREELEELLERGARGEVQVTPWLRFVVEQFLYAWWPYLDEATKFIELDKIYRV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BXS1-1", "uniprot_id": "IDI2_HUMAN", "id": "Q9BXS1-1", "name": "Isopentenyl-diphosphate delta-isomerase 2", "aln": "-----------------------------------------------------MSDINLDWVDRRQLQRLEEMLIVVDENDKVIGADTKRNCHLNE-NIEKGLLHRAFSVVLFNTKNRILIQQRSDTKVTFPGYFTDSCSSHPLYNPAELEEK-----DAIGVRRAAQRRLQAELGIPGEQISPE-DIVFMTIYHHKAKSDRIWGEHEICYLLLVRK----NVTLNPDPSETKSILYLSQEELWELLEREARGEVKVTPWLRTIAERFLYRWWPHLDDVTPFVELHKIHRV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JYZ4-1", "uniprot_id": "A0A0G2JYZ4_RAT", "id": "A0A0G2JYZ4-1", "name": "isopentenyl-diphosphate Delta-isomerase", "aln": "-----------------------------------------------------MFQASKTHLNELQIKRLEEILIVIDKQDQIIGADTKRNCHLME-TINKGLLHRGFSVVLFNTQNQLLVQQRADAKYTFPGHFTDSCSSHPLYVPEELEEE-----DAVGVRRAALRRLQAELGIPQDQTSIM-DSIFMNRIYHKSPSDDIWGDHENGYLLLVR-----------DPREVRSYSYMSQEDVQELLDRGTRGEEKITPWFRTIAEGFLLSWWPHLEDVSPFVEPDKIYGL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AD97-1", "uniprot_id": "A0A8I6AD97_RAT", "id": "A0A8I6AD97-1", "name": "isopentenyl-diphosphate Delta-isomerase", "aln": "-----------------------------------------------------MFQASKTHLNELQIKCLEEIVIVIDKQDQIIGADTKRNCHLME-NIDKGLLHRGFSVVLFNTQNQLLVQRRADAKYTFPGHFTDSCSSHPLYVPEELEEE-----DAVGVRRAALRRLQAELGIPQDQISIM-DIIFMNRIYHKSPSDDIWGDHEIGYLLLVRK----DLTLNPDPREVRSYSYMSQEDVQELLDRGTRGEEKITPWFRTIAEGFLLSWWPHLEDVSPFVEPDKIYGL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LU59-1", "uniprot_id": "A0ABK0LU59_RAT", "id": "A0ABK0LU59-1", "name": "isopentenyl-diphosphate Delta-isomerase", "aln": "-----------------------------------------------------MFQASKTHLNELQIKRLEEILIVIDKQDQIIGADTKRNCHLME-NINKGLLHRGFSVVLFNTQNQLLVQQRADAKYTFPGHFTDSCSSHPLYVPEELEEE-----DALGVRRAALRRLQAELGIPQDQISIK-DITFMTRKYQKCQSDAVWGDHEIGYLLLVRK----DLTLNPDPREVRSYSYMSQEDVQELLDREARGAEKITPWFRSMVEDFLLPWWPYLEDVSPFVEPDKIYGL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFZ6-1", "uniprot_id": "IDI2_MOUSE", "id": "Q8BFZ6-1", "name": "Isopentenyl-diphosphate delta-isomerase 2", "aln": "-----------------------------------------------------MFQASKTHLDELQLKRLEEMCIVIDKQDQIIGADTKKNCHLME-NINKGLLHRAFSVVLFNMKNELLVQQRADAKYTFPGHFTDSCSSHPLYVPEELEEK-----DALGVRRAALRRLQAELGISQDQISIK-DIIFMTRKYHKCQSDAIWGEHEIGYLLLVRK----DLMLNPDTREVRRCCYMSQKDVQELLDREARGEEKITPWFRSMVEDFLFSWWPHLEDVSSFVEPDKIYGL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58044-1", "uniprot_id": "IDI1_MOUSE", "id": "P58044-1", "name": "Isopentenyl-diphosphate Delta-isomerase 1", "aln": "-----------------------------------------------------MPEINTSHLDEKQVQLLAEMCILIDENDNKIGADTKKNCHLNE-NIDKGLLHRAFSVFLFNTENKLLLQQRSDAKITFPGCFTNSCCSHPLSNPGELEEN-----NAIGVKRAAKRRLKAELGIPLEEVDLN-EMDYLTRIYYKAQSDGIWGEHEVDYILFLRK----NVTLNPDPNEIKSYCYVSKEEVREILKKAASGEIKLTPWFKIIADTFLFKWWDNLNHLSPFVDHEKIHRL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35760-1", "uniprot_id": "IDI1_RAT", "id": "O35760-1", "name": "Isopentenyl-diphosphate Delta-isomerase 1", "aln": "-----------------------------------------------------MPEINASNLDEKQVQLLAEMCILIDENDNKIGADTKKNCHLNE-NIDKGLIHRAFSVFLFNTENKLLLQQRSDAKITFPGCFTNSCCSHPLNNPGELEEN-----DAMGVKRAAQRRLKAELGIPLEEVDLN-EMNYLTRIYYKAQSDGIWGEHEIDYILFLRK----NVTLNPDPNEIKSYCYVSKEELKEILKKEARGEIKLTPWFKIIADAFLFKWWDNLNHLSPFVDHEKIHRM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13907-1", "uniprot_id": "IDI1_HUMAN", "id": "Q13907-1", "name": "Isopentenyl-diphosphate Delta-isomerase 1", "aln": "-----------------------------------------------------MPEINTNHLDKQQVQLLAEMCILIDENDNKIGAETKKNCHLNE-NIEKGLLHRAFSVFLFNTENKLLLQQRSDAKITFPGCFTNTCCSHPLSNPAELEES-----DALGVRRAAQRRLKAELGIPLEEVPPE-EINYLTRIHYKAQSDGIWGEHEIDYILLVRK----NVTLNPDPNEIKSYCYVSKEELKELLKKAASGEIKITPWFKIIAATFLFKWWDNLNHLNQFVDHEKIYRM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P15496-1", "uniprot_id": "IDI1_YEAST", "id": "P15496-1", "name": "Isopentenyl-diphosphate delta-isomerase", "aln": "MTADNNSMPHGAVSSYAKLVQNQTPEDILEEFPEIIPLQQRPNTRSSETSNDESGETCFSGHDEEQIKLMNENCIVLDWDDNAIGAGTKKVCHLME-NIEKGLLHRAFSVFIFNEQGELLLQQRATEKITFPDLWTNTCCSHPLCIDDELGLKGKLDDKIKGAITAAVRKLDHELGIPEDETKTRGKFHFLNRIHYMAPSNEPWGEHEIDYILFYKINAKENLTVNPNVNEVRDFKWVSPNDLKTMFADPS---YKFTPWFKIICENYLFNWWEQLDDLSEVENDRQIHRML", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VDC2-1", "uniprot_id": "Q9VDC2_DROME", "id": "Q9VDC2-1", "name": "isopentenyl-diphosphate Delta-isomerase", "aln": "-----------------------MLASRLNLLLPRVSWLRGCSTTAVGQKHQRQVPTEFAVHDPLQAHALKEQCILVDANDQAIGAASKADCHRVHPETNDVKLHRAFSVFLFNSQGEMLVQKRSSHKITFPNTYTNACCSHPLYEIEQERQER----NAQGIRVAAQRRLNYELGIPTEELQPQ-DFRYLTRIHYADTGDGVWGEHEIDYILFLQK----DVTLRPNSNEVSEVRYLRRDKIDEAVAKFS---APLTPWFSLILQHRLKLWWDNLHQLEQFEDLSNIQRF-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . : * *::* :*: *** :: ** . :. :**.*** :** : .:*:*:*: * ***. ::::*.**** : . . * ** *:*. ****. :: . ::. : .: **:** *:*: : : * :: ..: . : .***: : * ** *.. . : :* . ", "identical_positions": 53, "similar_positions": 63, "identity": "18.15%" }, { "cls_id": "homologset.agr.SGD:S000006040", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADE8-1", "uniprot_id": "D4ADE8_RAT", "id": "D4ADE8-1", "name": "RNA helicase", "aln": "-------------------------MSHVAVENALGLDQQFAGLDLNSSDNQTGG--------STASKGRYIPP-------------HLR----NREATK------------GFYDKDSSGWSSSKDKDAYS------SFGSRGDSRGKSSFF-------GDRG--SGSRGR-----------------FDDRGR---------------GDYDGIGGRGDR-----------SGFGK---FERG---------------GNSRWCDKSDEDDWSKPLPPS-------------------------------------------------ERLEQELFSGGN------TGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYADGPGEALRAMK----ENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGAEIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLD-EYIFLAVGRVGSTSENITQKVVWVEEIDKRSFLLDLLNAT-----------------GKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV-----------------------AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFN-ERNINITKDLLDLLVEAKQEVPSWLENMAFEHHYKGSSR-GRSKSSRFSGGFGARDYRQSSGASSSSFSS----SRASSSRSGGGGHGSSRGFGGG--GYGGFYNS--------DGYGG---NYNSQGVDWWGN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62167-1", "uniprot_id": "DDX3X_MOUSE", "id": "Q62167-1", "name": "ATP-dependent RNA helicase DDX3X", "aln": "-------------------------MSHVAVENALGLDQQFAGLDLNSSDNQSGG--------STASKGRYIPP-------------HLR----NREATK------------GFYDKDSSGWSSSKDKDAYS------SFGSRGDSRGKSSFF-------GDRG--SGSRGR-----------------FDDRGR---------------GDYDGIGGRGDR-----------SGFGK---FERG---------------GNSRWCDKSDEDDWSKPLPPS-------------------------------------------------ERLEQELFSGGN------TGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYADGPGEALRAMK----ENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGAEIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLD-EYIFLAVGRVGSTSENITQKVVWVEEIDKRSFLLDLLNAT-----------------GKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV-----------------------AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFN-ERNINITKDLLDLLVEAKQEVPSWLENMAFEHHYKGSSR-GRSKSSRFSGGFGARDYRQSSGASSSSFSS----SRASSSRSGGGGHGGSRGFGGG--GYGGFYNS--------DGYGG---NYNSQGVDWWGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00571-1", "uniprot_id": "DDX3X_HUMAN", "id": "O00571-1", "name": "ATP-dependent RNA helicase DDX3X", "aln": "-------------------------MSHVAVENALGLDQQFAGLDLNSSDNQSGG--------STASKGRYIPP-------------HLR----NREATK------------GFYDKDSSGWSSSKDKDAYS------SFGSRSDSRGKSSFF-------SDRG--SGSRGR-----------------FDDRGR---------------SDYDGIGSRGDR-----------SGFGK---FERG---------------GNSRWCDKSDEDDWSKPLPPS-------------------------------------------------ERLEQELFSGGN------TGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMK----ENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLD-EYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNAT-----------------GKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV-----------------------AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFN-ERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSR-GRSKSSRFSGGFGARDYRQSSGASSSSFSS----SRASSSRSGGGGHGSSRGFGGG--GYGGFYNS--------DGYGG---NYNSQGVDWWGN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P16381-1", "uniprot_id": "DDX3L_MOUSE", "id": "P16381-1", "name": "Putative ATP-dependent RNA helicase Pl10", "aln": "-------------------------MSHVAEEDELGLDQQLAGLDLTSRDSQSGG--------STASKGRYIPP-------------HLR----NREAAK------------AFYDKDGSRWS--KDKDAYS------SFGSRSDTRAKSSFF-------SDRGG-SGSRGR-----------------FDERGR---------------SDYESVGSRGGR-----------SGFGK---FERG---------------GNSRWCDKADEDDWSKPLPPS-------------------------------------------------ERLEQELFSGGN------TGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALRAMK----ENGKYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLD-EYIFLAVGRVGSTSENITQKVVWVEEADKRSFLLDLLNAT-----------------GKDSLILVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV-----------------------AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFN-ERNINITKDLLDLLVEAKQEVPSWLENMAFEHHYKGGSR-GRSKS-RFSGGFGARDYRQSSGASSSSFSS----GRASNSRSGGGSHGSSRGFGGG--SYGGFYNS--------DGYGG---NYSSQGVDWWGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15523-1", "uniprot_id": "DDX3Y_HUMAN", "id": "O15523-1", "name": "ATP-dependent RNA helicase DDX3Y", "aln": "-------------------------MSHVVVKNDPELDQQLANLDLNSEKQSGGA--------STASKGRYIPP-------------HLR----NREASK------------GFHDKDSSGWSCSKDKDAYS------SFGSR-DSRGKPGYF-------SERG--SGSRGR-----------------FDDRGR---------------SDYDGIGNR-ER-----------PGFGR---FERS---------------GHSRWCDKSVEDDWSKPLPPS-------------------------------------------------ERLEQELFSGGN------TGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVK----ENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLD-EYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGAT-----------------GSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV-----------------------AARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFN-EKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSR-GRSKSNRFSGGFGARDYRQSSGSSSSGFGA----SRGSSSRSGGGGYGNSRGFGGG--GYGGFYNS--------DGYGG---NYNSQGVDWWGN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62095-1", "uniprot_id": "DDX3Y_MOUSE", "id": "Q62095-1", "name": "ATP-dependent RNA helicase DDX3Y", "aln": "-------------------------MSQVAAESTAGLDQQFVGLDLKSSDNQNGGG-------NTESKGRYIPP-------------HLR----NRETSK------------GVCDKDSSGWSCSKDKDAYS------SFGSR-DSRGKPNYF-------SDRG--SGSRGR-----------------FDDHGR---------------NDYDGIGGR-DR-----------TGFGK---FERS---------------GHSRWSDRSDEDDWSKPLPPS-------------------------------------------------ERLEQELFSGGN------TGINFEKYDDIPVEATGNNCPPHIENFSDIEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAMK----ENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADTVQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLD-EYIFLAVGRVGSTSENITQKVVWVEELDKRSFLLDLLNAT-----------------GKDSLTLVFVETKKGADSLENFLFQERYACTSIHGDRSQKDREEALHQFRSGRKPILVATAV-----------------------AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFN-ERNLNITKDLLDLLVEAKQEVPSWLESMAYEHHYKGSSR-GRSKS-RFSGGFGARDYRQSSGSANAGFNS----NRANSSRSSGSSHN--RGFGGG--GYGGFYNN--------DGYGG---NYNSQAVDWWGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A7A4-1", "uniprot_id": "A0A8I6A7A4_RAT", "id": "A0A8I6A7A4-1", "name": "RNA helicase", "aln": "----------------------------MAAENTVGLDQQFAGLDMNS-DNQNGGV-------STESKGRYIPP-------------HLR----NRETSK------------GVCDKDNSGWS--KDKDAYS------SFGSR-DSRGKPNYF-------SDRG--SGSRGR-----------------FDDPGR---------------SDYDCIASR-DR-----------SGFGK---FERS---------------GYSRWGDKSDEDDWSKPLPPS-------------------------------------------------ERLEQELFSGGN------TGINFEKYDDIPVEATGNNCPPHIENFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAMK----ENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADTVQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLD-EYIFLAVGRVGSTSENITQKVVWVEELDKRSFLLDLLNAT-----------------GKDSLTLVFVETKKGADSLENFLFQERYACTSIHGDRSQKDREEALHQFRSGRKPILVATAVCIFYFLVILSDCYFNLISIIFQVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFN-ERNLNITKDLLDLLVEAKQEVPSWLESMAYEHHYKGNSR-GRSK--RFSGGFGARDYRQSSGYANSGFNN----NRANSSRTSGSTHN--RGFGGG--GYGGFYSN--------EGYGG---NYNSQAVDWWGN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2BG36-1", "uniprot_id": "A0A8M2BG36_DANRE", "id": "A0A8M2BG36-1", "name": "RNA helicase", "aln": "-------------------------MSHVAVENVHGLDQQLAALDLSSADVQGVT------------GRRYIPP-------------HLR----NKEAAKNDAPG-------GWDNGRSNGFVNGYHDGRDN------RMNGGSSFAGRGPIR-------SDRGGRGGFRGKSTGSYNPIQPMQSAGFGYDNKDAGGWNV-------PKDNAYNSFGGRSDRGKSSFFNDRGSSSRGR---YERGGFGGG----------GNSRWVEECRDEDWSKPLPPN-------------------------------------------------ERLEHELFSGSN------TGINFEKYDDIPVEATGHNGPQPIDSFHDLEMGEIIMGNINLSRYTRPTPVQKHAIPIIKSKRDLMACAQTGSGKTAAFLLPVLSQIYTDGPGEALQAAKNSAQENGKYGRRKQYPISLVLAPTRELALQIYDEARKFSYRSHVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDYCNYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGLRQTMMFSATFPKEIQILARDFLE-DYIFLAVGRVGSTSENITQKVVWVEENDKRSFLLDLLNATVIPSEVQESTGESVEKPGKDSLTLVFVETKKGADALEDFLYREGYACTSIHGDRSQRDREEALHQFRSGRCPILVATAV-----------------------AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFN-DKNGNITKDLLDILVEAKQEVPSWLESLAYEHQHKSSSR-GRSK--RFSGGFGARDYRQNSSSGGGGFG-------GRGGRSTG-GHGGNRGFGGGKGGFGNFYSS--------DGYGG---NYS--QVDWWGN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHP0-1", "uniprot_id": "DDX3_DROME", "id": "Q9VHP0-1", "name": "ATP-dependent RNA helicase bel", "aln": "-------------------------MSNAINQNGTGLEQQVAGLDLNGGSADYSGPITSKTSTNSVTGGVYVPP-------------HLRGGGGNNNAADAESQGQGQGQGQGFDSRSGNPRQETRDPQQSRGGGGEYRRGGGGGGRGFNRQS-------GDYGYGSGGGGRRGGGGRFEDN--YNGGEFDSRRG---------------GDWNRSGGGGGGG----------RGFGRGPSYRGGGGGSGSNLNEQTAEDGQAQQQQQPRNDRWQEPERPAGFDGSEGGQSAGGNRSYNNRGERGGGGYNSRWKEGGGSNVDYTKLGARDERLEVELFGVGN------TGINFDKYEDIPVEATGQNVPPNITSFDDVQLTEIIRNNVALARYDKPTPVQKHAIPIIINGRDLMACAQTGSGKTAAFLVPILNQMYELGHVPPPQSTR-------QYSRRKQYPLGLVLAPTRELATQIFEEAKKFAYRSRMRPAVLYGGNNTSEQMRELDRGCHLIVATPGRLEDMITRGKVGLENIRFLVLDEADRMLDMGFEPQIRRIVEQLNMPPTGQRQTLMFSATFPKQIQELASDFLS-NYIFLAVGRVGSTSENITQTILWVYEPDKRSYLLDLLSSIRDGPE-----------YTKDSLTLIFVETKKGADSLEEFLYQCNHPVTSIHGDRTQKEREEALRCFRSGDCPILVATAV-----------------------AARGLDIPHVKHVINFDLPSDVEEYVHRIGRTGRMGNLGVATSFFN-EKNRNICSDLLELLIETKQEIPSFMEDMSSDRGHGGAKRAGRGGGGRYGGGFGSRDYRQSSGGGGGGRSGPPPRSGGSGSGGGGGSYRSNGNSYGGNSGGGGYYGGGAGGGSYGGSYGGGSASHSSNAPDWWAQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24784-1", "uniprot_id": "DBP1_YEAST", "id": "P24784-1", "name": "ATP-dependent RNA helicase DBP1", "aln": "---------------------------------MADLPQKVSNLSINNKENGGGG-----------GKSSYVPP-------------HLR----SR-------------------GKPSFERSTPKQEDKVT----------------GGDFF-------RRAGRQTGNNGG-----------------FFGFSK------------------ERNGGTSAN-------------------YNRG---------------GSSNYKSSGNRWVNGKHIPGP-----------------------------------------------KNAKLEAELFGVHDDPDYHSSGIKFDNYDNIPVDASGKDVPEPILDFSSPPLDELLMENIKLASFTKPTPVQKYSIPIVTKGRDLMACAQTGSGKTGGFLFPLFTELFRSGPSPVPEKAQ-------SFYSRKGYPSALVLAPTRELATQIFEEARKFTYRSWVRPCVVYGGAPIGNQMREVDRGCDLLVATPGRLNDLLERGKVSLANIKYLVLDEADRMLDMGFEPQIRHIVEECDMPSVENRQTLMFSATFPVDIQHLARDFLD-NYIFLSVGRVGSTSENITQRILYVDDMDKKSALLDLLSAE------------------HKGLTLIFVETKRMADQLTDFLIMQNFKATAIHGDRTQAERERALSAFKANVADILVATAV-----------------------AARGLDIPNVTHVINYDLPSDIDDYVHRIGRTGRAGNTGVATSFFN-SNNQNIVKGLMEILNEANQEVPTFLSDLSRQNSRGGRTR--GGGGFFNSRNNGSRDYRKHGG--NGSFGS---------TRPRNTGTSNWGSIGGG------FRND--------NEKNG----YGNSNASWW--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9NQI0-1", "uniprot_id": "DDX4_HUMAN", "id": "Q9NQI0-1", "name": "Probable ATP-dependent RNA helicase DDX4", "aln": "MGDEDWEAEINPHMSSYVPIFEKDRYSGENGDNFNRTPASSSEMDDGPSRRDHFMK-------SGFASGRNFGNRDAGECNKRDNTSTMGGFGVGKSFGNRGFSNS------RFEDGDSSGFWRESSNDCEDNPTRNRGFSKRGGYRDGNNSEASGPYRRGGRGSFRGCRGGFG-----------LGSPNNDLDPDECMQRTGGLFGSRRPVLSGTGNGDTSQ----------SRSGSG--SERGGYKG-LNEEVITGS-GKNSWKSEAEGGESSDTQGPK-------------------------------------------VTYIPPPPPEDEDSIFAH----YQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITA-------------SRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNI------------------GDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSV-----------------------AARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEIAFSTYIPGFSG----------------------STRGNVFAS-------VDTRKGKSTLNTAGFSSSQ--------------------------APNPVDDESWD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09052-1", "uniprot_id": "VASA1_DROME", "id": "P09052-1", "name": "ATP-dependent RNA helicase vasa", "aln": "MSD-DWDDE---------PIVDTR---GARGGDWSDDEDTAKSFS-GEAEGDGVGG-------SGGEGGGYQGG----------NRDVFGRIGGGRGGGAGGYRGG------NRDGGGFHGGRREGERDFRGGEGGFRGG--QGGSRGGQGG------SRGGQGGFRGGEGGF------------RGRLYENEDGDE-----------RRGRLDREERGGERR----------GRLDR---EERGGERGERGDGGFARR-RRNEDDINNNNNIVEDVERKR-------------------------------------------EFYIPPEPSNDAIEIFSSG---IASGIHFSKYNNIPVKVTGSDVPQPIQHFTSADLRDIIIDNVNKSGYKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLED-----------------PHELELGRPQVVIVSPTRELAIQIFNEARKFAFESYLKIGIVYGGTSFRHQNECITRGCHVVIATPGRLLDFVDRTFITFEDTRFVVLDEADRMLDMGFSEDMRRIMTHVTMRP--EHQTLMFSATFPEEIQRMAGEFLK-NYVFVAIGIVGGACSDVKQTIYEVNKYAKRSKLIEILSEQ------------------ADG-TIVFVETKRGADFLASFLSEKEFPTTSIHGDRLQSQREQALRDFKNGSMKVLIATSV-----------------------ASRGLDIKNIKHVINYDMPSKIDDYVHRIGRTGRVGNNGRATSFFDPEKDRAIAADLVKILEGSGQTVPDFLRTCG-----AGGDG----------------------GYSNQNFGG-------VDVR-GR------GNYVGD--------------------------ATNVEEEEQWD-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : .. . * * * . . . . : :**:*.:*: * *..:* : * * * . : : : *: : : **:** :**:: **************..**.*:: .: . * ::::*****. **: **:**:: : :: ::*** .. . : :**.:: ****** *:: : : : .::************* :::::: * . ::*:******* :** :* :**. :*:*:::* **.:. :: * : * . *:. *:::* . ::*****: ** : ** *:***** * :**.** *: . :*:**:* *:***** :: ****:*:** :::********** ** * * ***: . : : *:.:* : * :* :: . . . . . . . * ", "identical_positions": 158, "similar_positions": 139, "identity": "17.19%" }, { "cls_id": "homologset.agr.SGD:S000006041", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M4I5-1", "uniprot_id": "F1M4I5_RAT", "id": "F1M4I5-1", "name": "", "aln": "------MSP-----ALFLCHRCNEPLKLLQQ--------------------QGGPLEVQHHANLPTEMPVSGQ---------SRVRTSHRAHSDGGRTCQG------------------------GACCTFTLLGES---VSVRT-----------LHTVQNTTIEIFEILSEQKVVDHPLCVDCTDNLLVQLDDQLTLVASDNQSYQGFLERQS----LVSEEETEALHAELRAELSGLEQEEARLVQELEDLDGHHARVAAELRAAQAESKELYQQNEEHRASYSVLKMEQLELTDQLSSVENQLQYALGQLCHLRKTSIFDATFTISDDGPLGMINNFRLGCLPAVRVGWTEINAAWGQTALLLFSLSKMAGLQFQRYQLVPLGDHSYLKS--------------LTAD-EVLPLFSDG----NHSVFLNNTFDCAMKAFLDCLQQFVEETEKDERYPCLP----YRIHPLEGVMEDIGDSGDCCPIRTHLNTEEE---------------WSRALKFMLADLKLIVAWASSRCSR------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0DM65-1", "uniprot_id": "BECN2_MOUSE", "id": "P0DM65-1", "name": "Beclin-2", "aln": "------MSP-----ALFLCQRCKEPLKLLQQ--------------------QGGPLEVQHHANTPTEIPVSAE---------SQVRTSGRPHSDGGRVSQGSALCTFTLLTSGGPDSEGGTTSQGNACCTFTLLGES---ASMRT-----------MNTIQNTVLETFEILSDQKVVDHPLCVDCTDHLLMQLDDQLALLASDNQKYKSFQDREL----LVSEEEREALHAELCAELSSLEQEEARLTQELEDLDGHHARVAAELRAAQAESKELYKQHEQHRVEYSVFKMEQLELMDQLSSVENQLTYALSQQYRLRQTNIFNATFTISDEGPLGVINNFRLGCLPGVRVGWTEISSAWGQTVLLLFSLSKIAGLQFQRYQLVPFGDHSYLKS--------------LTGD-GVLPLFSDG----SHSVFLNNKFDCGMKAFLDCLQQFVEEIERDERCPCLP----YRIHVKEGLMEDVWDSGECCSIRTHLNTEEE---------------WSRALKFMLSDLKLILAWASLRFSRVQRP--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MW95-1", "uniprot_id": "BECN2_HUMAN", "id": "A8MW95-1", "name": "Beclin-2", "aln": "------MSS-----IRFLCQRCHQALKLSGSSESRS-----LPAAPAPTSGQAEPGDTREPGVTTREVTDAEE---------QQDGASSRSPPGDGSVSKG-------------------------HANIFTLLGEL---GAMHM-----------LSSIQKAAGDIFDIVSGQAVVDHPLCEECTDSLLEQLDIQLALTEADSQNYQRCLETGE----LATSEDE---AAALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKEINCFTATFEIWVEGPLGVINNFRLGRLPTVRVGWNEINTAWGQAALLLLTLANTIGLQFQRYRLIPCGNHSYLKS--------------LTDDRTELPLFCYG----GQDVFLNNKYDRAMVAFLDCMQQFKEEAEKGELGLSLP----YGIQVETGLMEDVGGRGECYSIRTHLNTQEL---------------WTKALKFMLINFKWSLIWVASRYQK------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88597-1", "uniprot_id": "BECN1_MOUSE", "id": "O88597-1", "name": "Beclin-1", "aln": "-MEGSKASS-STMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEEANSGEEPFIET---------RQDGVSRRFIPPARMMSTES-------------------------ANSFTLIGEASDGGTMEN-----------LSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILE----QMNEDDS----EQLQRELKELALEEERLIQELEDVEKNRKVVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQVRYAQIQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLES--------------LTDKSKELPLYCSG----GLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLP----YRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQ---------------WTKALKFMLTNLKWGLAWVSSQFYNK-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91XJ1-1", "uniprot_id": "BECN1_RAT", "id": "Q91XJ1-1", "name": "Beclin-1", "aln": "-MEGSKASS-STMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGESQEEEANSGEEPFIET---------RQDGVSRRFIPPARMMSTES-------------------------ANSFTLIGEASDGGTMEN-----------LSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEMLE----QMNEGDS----EQLQRELKELALEEERLIQELEDVEKNRKVVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQMQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSAPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLES--------------LTDKSKELPLYCSG----GLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLP----YRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQ---------------WTKALKFMLTNLKWGLAWVSSQFYNK-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14457-1", "uniprot_id": "BECN1_HUMAN", "id": "Q14457-1", "name": "Beclin-1", "aln": "-MEGSKTSNNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETP--------RQDGVSRRFIPPARMMSTES-------------------------ANSFTLIGEASDGGTMEN-----------LSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILE----QMNEDDS----EQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLES--------------LTDKSKELPLYCSG----GLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLP----YRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQ---------------WTKALKFMLTNLKWGLAWVSSQFYNK-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RCP1-1", "uniprot_id": "BECN1_DANRE", "id": "F1RCP1-1", "name": "Beclin-1", "aln": "-METLRFSS-NTMQVSFVCQRCNQPLKLDTSFNVLDRMTIHELTAPLVMVTANKQQDSGESSSFP-EETFLEN---------KQDGVARKFIPPARMMSAES-------------------------TNSFTLIGEASDGGTMEN-----------LSRRLKVTSNLFDIMSGQTDIDHPLCEECTDTLLDHLDTQLNITENECQNYKSCLELLS----QLPEEEE----ASLLNALQQLKQEEESLIQELESIETKREAVAKELDEGRNHSQLMDTEELRYQKEYCEFKRQQLELDDDLKSVDNQMRYCQIQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALASKMGLCFQRYQLVPYGNHSYLES--------------LSDKSKELPLYCSG----GLRFFWDNKFDHAMVAFLDCVQQFKEEVEKDDTGFCLP----YRMDVDKGKIEDTGGSGGSYSIKTQFNSEEQ---------------WTKALKFMLTNLKWGLAWVSSQFYNR-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCE1-1", "uniprot_id": "BECN1_DROME", "id": "Q9VCE1-1", "name": "Beclin-1-like protein", "aln": "------MSEAEKQAVSFACQRCLQPIVLDEQLEK-----------------ISVHAMAELSLPIYGDNGNTLDP--------QDASSFDHFVPPYRLTDSIN-------------------------GTGFMLVSDG---RDNKK-----------MSAAFKLKAELFDCLSSNSEIDHPLCEECADSMLEIMDRELRIAEDEWDVYKAYLDELE----QQRVAPN---VEALDKELDELKRSEQQLLSELKELKKEEQSLNDAIAEEEQEREELHEQEESYWREYTKHRRELMLTEDDKRSLECQIAYSKQQLDKLRDTNIFNITFHIWHAGHFGTINNFRLGRLPSVSVDWSEINAAWGQTVLLLSALARKIGLTFERYRVVPFGNHSYVEV--------------LGEN-RELPLYGSG----GFKFFWDTKFDAAMVAFLDCLTQFQKEVEKRDTEFLLP----YKMEK--GKIIDP-STGNSYSIKIQFNSEEQ---------------WTKALKFMLTNLKWGLAWVSSQFVSP-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02948-1", "uniprot_id": "BECN1_YEAST", "id": "Q02948-1", "name": "Vacuolar protein sorting-associated protein 30", "aln": "MKCQTCHLPLQLDPSLEGLSLTQRNLLLSNNSIITATNENVISNKGIEAADNCGPQIPKERLRRLGEIQNIKDLNLKDDKLITDSFVFLNHDDDDNANITSNSREDQRYGNANGNDNKKANSDTSDGTSTFRDHDEEEQEATDEDENQQIQLNSKTLSTQVNAMTNVFNILSSQTNIDFPICQDCCNILINRLKSEYDDAIKERDTYAQFLSKLESQNKEISESNKEKQYSHNLSEKENLKKEEERLLDQLLRLEMTDDDLDGELVRLQEKKVQLENEKLQKLSDQNLMDLNNIQFNKNLQSLKLQYELSLNQLDKLRKINIFNATFKISHSGPFATINGLRLGSIPESVVPWKEINAALGQLILLLATINKNLKINLVDYELQPMGSFSKIKKRMVNSVEYNNSTTNAPGDWLILPVYYDENFNLGRIFRKETKFDKSLETTLEIISEITRQLSTIASSYSSQTLTTSQDESSMNNANDVENSTSILELPYIMNKDKINGLSVKLHGSSPNLEWTTAMKFLLTNVKWLLAFSSNLLSKSITLSPTVNYNDKTISGN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * . : . * .: . : : : *: :* : :*.*:* :* : :: :. : : : * . * .* * .:* :. : . . : :. . : : .: .:. * . * :*:. . * ** * * :. **.:*** :* * *.**.:* ** *** :: : : *.: * *..* :: . **:: . . :..:* .: : *: : :: .: . . . * . : :*.:: *: *:**:* :.* : : : ", "identical_positions": 53, "similar_positions": 104, "identity": "9.52%" }, { "cls_id": "homologset.agr.SGD:S000006043", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q92759-1", "uniprot_id": "TF2H4_HUMAN", "id": "Q92759-1", "name": "General transcription factor IIH subunit 4", "aln": "MESTPSRG------------------LNRVHLQCRNLQEFLGG-LSPGVLDRLYGHPATCLAVFRELPSLAKNWVMRMLFLEQPLPQAAVALWVKKEFSKAQEESTGLLSGLRIWHTQLLPGGLQGLILNPIFRQNLRIALLGGGKAWSDDTSQLGPDKHARDVPSLDKYAEERWEVVLHFMVGS------PSAAVSQDLAQLLSQAGLMKSTEPGEPPCITSAGFQFLLLDTPAQLWYFMLQYLQTAQSRGMDLVEILSFLFQLSFSTLGKDYSVEGMSDSLLNFLQHLREFGLVFQRKRKSRRYYPTRLAINLSSG-------------------------VSGAGG-------TVHQP------------GFIVVETNYRLYAYTESELQIALIALFSEMLYRFPNMVVAQVTRESVQQAIASGITAQQIIHFLRTRAHPVM------------------LKQTPVLPPTITDQIRLWELERDRLRFTEGVLYNQFLSQVDFELLLAHARELGVLVFENSAKRLMVVTPAGHSDVKRFWKRQKHSS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O70422-1", "uniprot_id": "TF2H4_MOUSE", "id": "O70422-1", "name": "General transcription factor IIH subunit 4", "aln": "MEITPARGG-----------------LNRAHLQCRNLQEFLGG-LSPGVLDRLYGHPATCLAVFRELPSLAKNWVMRMLFLEQPLPQAAVALWVKKEFSKAQEESTGLLSGLRIWHTQLLPGGLQGLILNPVFRQNLRIALLGGGKAWSDDTSQLGPDKHARDVPSLDKYAEERWEVVLHFMVGS------PSAAVSQDLAQLLSQAGLMKSTEPGEPPCITSAGFQFLLLDTPAQLWYFMLQYLQTAQSRGMDLVEILSFLFQLSFSTLGKDYSVEGMSDSLLNFLQHLREFGLVFQRKRKSRRYYPTRLAINLSSG-------------------------VSGAGG-------TVHQP------------GFIVVETNYRLYAYTESELQIALIALFSEMLYRFPNMVVAQVTRESVQQAIASGITAQQIIHFLRTRAHPVM------------------LKQNPVLPPTITDQIRLWELERDRLRFTEGVLYNQFLSQVDFELLLAHARELGVLVFENSAKRLMVVTPAGHSDVKRFWKRQKHSS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VUR1-1", "uniprot_id": "Q9VUR1_DROME", "id": "Q9VUR1-1", "name": "General transcription factor IIH subunit 4", "aln": "MADTKSGSGRHSAAGGSGNAVLSPLGQGPANLECKDFQEYLRTRQTPESLEKLYNYPPICLAVFRELPEIARQFIIRILFVDQPVPQAVVTSWGAQRCAKEQAEATSCLTALNVWRVTAIPGGLSAWELSPTFKKSVRQVLLGGGKPWP-MTNTLDKDSKPRDIAFLDTYAMSRWRCVLHYMVGTGNRNGTDAEAISPDAVRILLHANLMKRDE-RDGITITRQGFQFLLLDTRAQVWHFMLQYLDTCEERGISLPECLSMLFQLSFSTLGRDYSSEGMNSQMLTFLQHLREFGLVFQRKRKEGRFYPTRLALNVTSK-------------------------EAAATASVAMDEEATQDC------------GYIVVETNYRVYAYTDSPLQVAVLGLFTELLYRFPNLVVGVLTRDSVRQALRGGITAEQIVSYLEQYAHPNMR------------MVESAIHSKSCLPPTVVDQIKLWELERNRFTYTEGVLYNQFLSHTDFVTLRDYAQSIHMLVWQNERTRTMVVQKNGHDDVKRYWKKYSKSGV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02939-1", "uniprot_id": "TFB2_YEAST", "id": "Q02939-1", "name": "General transcription and DNA repair factor IIH subunit TFB2", "aln": "----------------------------MSDYSLKHSVTQYLEEIPQQVQNRLYTSPATCLAIYRILPPLAKFFIMAMVFNENEVPLLDLDKWVNSNGKLQFQNAIKSMKSLHLLIPNKSSG-TLMINLNPTFKISLRNALTGG---EVQNSFGVVVEENVVSLDLLDEYSANKWETILHFMVGTP-----LAKIPSEKVLNLLKHSKLMEEVNSTGEFKITNEGFQFLLQEINSQLWTLLLQYLKMIETSKMDLVDVLHFIFMLGALEVGKAYKIDALSETQRIMLQDMRDYGLVFQKHSNDSIFYPTKLALMLTSDTKTIRSASNAMDSVLRQNREEPSVNEDGANGKSTTDITTSDDLNKAGLKNQDIPDGSLIVETNFKIYSYSNSPLQIAVLSLFVHLKARFVNMVLGQITRESIRRALTNGITADQIIAYLETHAHPQMRRLAEEKLEKKLELDPNCKEPLQVLPPTVVDQIRLWQLELDRVITYEGSLYSDFETSQEYNLLSKYAQDIGVLLWKDDKKKKFFISKEGNSQVLDFAKRKLKKKQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :. . ::** *. ***::* ** :*: ::: ::* :: :* : * .. :: :..*.: .* *.* *: .:* .* ** : : :.: .: ** *: .:*. :**:***: : * . .:* :: **: : ** ****** : :*:* ::****. : :.* : * ::* *. :*: *. :.:.. :**.:*::*****:: :. :***:**: ::* .* . : .: * ::****:::*:*::* **:*::.** .: ** *:*:. :**:*:::*: .****:**: :*. *** * . ****:.***:**:** :*. ** **.:* : :: * :*:.: :*::::. .: :.: *:.:* : *: :. ", "identical_positions": 125, "similar_positions": 160, "identity": "22.73%" }, { "cls_id": "homologset.agr.SGD:S000006044", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "C0HKG5-1", "uniprot_id": "RNT2A_MOUSE", "id": "C0HKG5-1", "name": "Ribonuclease T2-A", "aln": "-MAPAEARGALPGWISVLGWGLALCSLCGAGPLWSG------------------------------------SHEWKKLILTQHWPPTVCKEVN--------SCQDSLDYWTIHGLWPDRAED-----CNQSWHFN-------LDEIKDLLRDMKIYWPDVIH--------RSSNRSQFWKHEWVKHGTCAAQV-------------DALNSEKKYFGKSLDLYKQIDLNSVLQKFGIKPSI-NYYQLADFKDALTRIY-GVVPKIQCLMPEQGESVQTVGQIELCFTKEDLHLRNCTEPGEQLSSRQEAWLAM---EAS-THGMMVCED-GPIFYPPPTKTQH---------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZCH6-1", "uniprot_id": "D3ZCH6_RAT", "id": "D3ZCH6-1", "name": "", "aln": "---MAEARGALPGWVSVLGWGLALCCLCGAGPLWSG------------------------------------SHEWKKLILTQHWPPTVCKEVN--------RCRDSLDYWTIHGLWPDRAED-----CNHSWHFN-------LNEIKDLLRDMKIYWPDVIH--------PSSNRSQFWKHEWDKHGTCAAQV-------------DALNSERKYFGKSLDLYKQIDLNSVLQKFEIKPSI-NYYQLADFKDALTRIY-GVVPKIQCLMPEQGENVQTIGQIELCFTKEDFHLRNCTEPEEQPSSGQEARLAR---EAS-THGMMVCED-GPIFYPPP-KSQH---------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00584-1", "uniprot_id": "RNT2_HUMAN", "id": "O00584-1", "name": "Ribonuclease T2", "aln": "-MRPAALRGALLGCL-----CLALLCLGGADKRLRD------------------------------------NHEWKKLIMVQHWPETVCEKIQN-------DCRDPPDYWTIHGLWPDKSEG-----CNRSWPFN-------LEEIKDLLPEMRAYWPDVIH--------SFPNRSRFWKHEWEKHGTCAAQV-------------DALNSQKKYFGRSLELYRELDLNSVLLKLGIKPSI-NYYQVADFKDALARVY-GVIPKIQCLPPSQDEEVQTIGQIELCLTKQDQQLQNCTEPGEQPSPKQEVWLAN---GAAESRGLRVCED-GPVFYPPPKKTKH---------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8XY56-1", "uniprot_id": "RNT2_DANRE", "id": "B8XY56-1", "name": "Ribonuclease T2", "aln": "------MRFIAFAVI------FSAVYLCSS-AFTHP------------------------------------RGEWTKLILTQHWPQTFCKMEH---------CKTDFSYWTLHGLWPNTGVR-----CNTSWHFN-------ASLIEDILPEMEKFWPDLLE--------PSS--PKFWNYEWTKHGTCAAKS-------------ESLNSEHKYFGKALELYHKFDLNSVLLKNQIVPSE-KHYTLEDVEEAITSAY-GVKPKIQCVHPGQGGQVQILGQIEICVDR-DFQLMGCEKSSEDTWSNDLPTVPV---SGQ--SGLSVCDHSMPVYYPPVQA------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSC3-1", "uniprot_id": "Q9VSC3_DROME", "id": "Q9VSC3-1", "name": "", "aln": "MQSQRFLFVAILACFLVTIKSTPLSDISYSDESTSVNEKTQKRPDDDSEFDGFPFREDDDSLQDSSREMSVQDHNWDVLIFTQQWPVTTCYHWREENPDQECSLPQKKEFWTIHGIWPTKLHQMGPNFCNNSANFD-------PSKLNPIEDRLETFWPDLKG--------MDS-TEWLWKHEWQKHGTCAMLV-------------EELDNELKYFEQGLTWREEYIMSRILDASDIHPD--SNNTVAAINNAIVKAL-GKNPSIHCLYDGKHG-ISYLSEIRICFSK-SLELIDCDGIKQG--DAVPVGVPG---GTIITNCHIGSLVHYPSLVPPLQRKSHWKLPLVNVYKLLQFLMWFTL-------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0AB13A9V5-1", "uniprot_id": "A0AB13A9V5_DANRE", "id": "A0AB13A9V5-1", "name": "", "aln": "-MTYNKHILWAFTAALATGWVLSNDEGCYYGTVMKH------------------------------------SCNWTCMLLTLQWPGSFCIGLTN---KTICKIPLTIQNWTIHGLWPMHTGH-----CCNCWPIF-------HSHLQEIEPELTQLWPSLIK--------GKH-FFNFWREEWIKHGTCAGCD-------------GAMGSPLLYFQAAVKLRKLFDINSVLESSGIKASCEVSYKYDDISKALTSLL-GDNFDLQCVTDSKGREAWIQLKIHLSRNQ----TIGCPTEKQDEAFYNLAWYKS---PGH-PCPKNTTIFFVPINYDNPHEPCN---------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02933-1", "uniprot_id": "RNY1_YEAST", "id": "Q02933-1", "name": "Ribonuclease T2-like", "aln": "-MLLKNLHSLLQLPIFSNGADKGIEPNCPINIPLSCSNKTDIDN------------------------SCCFEYPGGIFLQTQFWNYFPSKNDLN--ETELVKELGPLDSFTIHGLWPDNCHGGYQQFCNRSLQIDDVYYLLHDKKFNNNDTSLQISGEKLLEYLDLYWKSNNGNHESLWIHEFNKHGTCISTIRPECYTEWGANSVDRKRAVYDYFRITYNLFKKLDTFSTLEKNNIVPSVDNSYSLEQIEAALSKEFEGKKVFIGCDRHNSLNEVWYYNHLKGSLLSEMFVPMDSLAIRTNCKKDGIKFFPKGYVPTFRRRPNKGARYRGVVRLSNINNGDQMQGFLIKNGHWMSQGTPANYELIKSPYGNYYLRTNQGFCDIISSSSNELVCKFRNIKDAGQFDFDPTKGGDGYIGYSGNYNWGGDTYPRRRNQSPIFSVDDEQNSKKYKFKLKFIKN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . * . . :*:**:** * . : . :: : .: :* *: ***** ** . * * .. .. *: * : * . .:. . .. ", "identical_positions": 21, "similar_positions": 32, "identity": "4.56%" }, { "cls_id": "homologset.agr.SGD:S000006046", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6APG6-1", "uniprot_id": "A0A8I6APG6_RAT", "id": "A0A8I6APG6-1", "name": "Importin-11", "aln": "MDLNSASSVVLQVLTQATS---QDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINVRWLAVLYFKHGIDRYWRRVAPHALSEEEKSTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWP----ELIPTLVESVKVQDDLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQQVSSGNEAAVLSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGFLHGIFERLKQFLECSRSIGTDNVCRDRLEKT----IILFTKVLLDFLDQHPISFTPLIQRSLEFSVSYVFTEVGEGVT---FERFIVQCMNLIKMIVKNYAYKPSKNFEDSS---PETLEAHKIKMAFFTYPTLTEICRRLVSHYFLLTEEELTMWEEDPEGFTVEETGGDSWKYSLRPCTEVLFIDIFHEYNQTLTPVLLEMMQTLQGPTNVEDMNALLIKDAVYNAVGLAAFELFDSVDFDQWFKTQLLPELQ---VSHNRYKPLRRRVIWLIGQWISVKFKSDLRPRLYEAICNLLQDQD-LVVRIETATTLKLTVDDFEFRTDQFLPYLET-MFTLLFQLLQQVTECDTKMHVLHVLSCVIERVN-IQIRPYVGCLVQYLPLLWKQSEEHN---MLRCAILTTLIHLVQGLGADSKNLYPFLLPVIQLSTDVSQPPHVYLLEDGLELWLVTLENSPCVTPELLRIFQNMSPLLELSSEN----LRTCFKIINGYIFLSS--TEFLQTYAAGLCQSFYELLPEITTEGQVQVLKVVENTLKVN-----PVLGPQMFQR-ILPYVFRGVIEGER-YPVVMSIYLAVMGRVLLQNASFFSSLLNEMGHEFN-------------------QEMDQLLGNVIEMWVDRMDNITQPERKKLSALALLSLLPSDNSVIQDKFCGIINISVEALHDVMTEDPETRTYKDCMLMSHHEEPKVTEDEEPPTEQDKRKKMLALKDPVHTVSLQQFIYEKLKAQQEILGEQGFQSLMETVDTEIVTQLQEFLQGF------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K2V6-1", "uniprot_id": "IPO11_MOUSE", "id": "Q8K2V6-1", "name": "Importin-11", "aln": "MDLNSASSVVLQVLTQATS---QDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINVRWLAVLYFKHGIDRYWRRVAPHALSEEEKSTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWP----ELIPTLVESVKVQDDLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQHVSSGNEAAVLSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGFLHGIFERLKQFLECSRSIGTDNVCRDRLEKT----IILFTKVLLDFLDQHPISFTPLIQRSLEFSVSYVFTEVGEGVT---FERFIVQCMNLIKMIVKNYAYKPSKNFEDSS---PETLEAHKIKMAFFTYPTLTEICRRLVSHYFLLTEEELTMWEEDPEGFTVEETGGDSWKYSLRPCTEVLFIDIFHEYNQTLTPVLLEMMQTLEGPTNVEDMNALLIKDAVYNAVGLAAFELFDSVDFDQWFKTQLLPELQ---VSHNRYKPLRRRVIWLIGQWISVKFKSDLRPMLYEAICNLLQDQD-LVVRIETATTLKLTVDDFEFRTDQFLPYLET-MFTLLFQLLQQVTECDTKMHVLHVLSCVIERVN-VQIRPYVGCLVQYLPLLWKQSEEHN---MLRCAILTTLIHLVQGLGADSKNLYPFLLPVIQLSTDVSQPPHVYLLEDGLELWLVTLENSPCVTPELLRIFQNMSPLLELSSEN----LRTCFKIINGYIFLSS--TEFLQTYAAGLCQSFYELLPEITTEGQVQVLKVVENALKVN-----PVLGPQMFQR-ILPCVFRGVIEGER-YPVVMSIYLAVMGRVLLQNTSFFSSLLNEMGHEFN-------------------QEMDQLLGNVIEMWVDRMDNITQPERKKLSALALLSLLPSDNSVIQDKFCGIINISVEALHDVMTEDPETRTYKDCMLMSQHEEPKVTEDEEPPTEQDKRKKMLALKDPVHTVSLQQFIYEKLKAQQEILGEQGFQSLMETVDTEIVTQLQEFLQGF------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UI26-1", "uniprot_id": "IPO11_HUMAN", "id": "Q9UI26-1", "name": "Importin-11", "aln": "MDLNSASTVVLQVLTQATS---QDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINVRWLAVLYFKHGIDRYWRRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWP----ELIPTLIESVKVQDDLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGFLHGIFERLKQFLECSRSIGTDNVCRDRLEKT----IILFTKVLLDFLDQHPFSFTPLIQRSLEFSVSYVFTEVGEGVT---FERFIVQCMNLIKMIVKNYAYKPSKNFEDSS---PETLEAHKIKMAFFTYPTLTEICRRLVSHYFLLTEEELTMWEEDPEGFTVEETGGDSWKYSLRPCTEVLFIDIFHEYNQTLTPVLLEMMQTLQGPTNVEDMNALLIKDAVYNAVGLAAYELFDSVDFDQWFKNQLLPELQ---VIHNRYKPLRRRVIWLIGQWISVKFKSDLRPMLYEAICNLLQDQD-LVVRIETATTLKLTVDDFEFRTDQFLPYLET-MFTLLFQLLQQVTECDTKMHVLHVLSCVIERVN-MQIRPYVGCLVQYLPLLWKQSEEHN---MLRCAILTTLIHLVQGLGADSKNLYPFLLPVIQLSTDVSQPPHVYLLEDGLELWLVTLENSPCITPELLRIFQNMSPLLELSSEN----LRTCFKIINGYIFLSS--TEFLQTYAVGLCQSFCELLKEITTEGQVQVLKVVENALKVN-----PILGPQMFQP-ILPYVFKGIIEGER-YPVVMSTYLGVMGRVLLQNTSFFSSLLNEMAHKFN-------------------QEMDQLLGNMIEMWVDRMDNITQPERRKLSALALLSLLPSDNSVIQDKFCGIINISVEGLHDVMTEDPETGTYKDCMLMSHLEEPKVTEDEEPPTEQDKRKKMLALKDPVHTVSLQQFIYEKLKAQQEMLGEQGFQSLMETVDTEIVTQLQEFLQGF------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02932-1", "uniprot_id": "KA120_YEAST", "id": "Q02932-1", "name": "Importin beta-like protein KAP120", "aln": "MASSLNELNLVQVLEQASNPQHIRSDVQKLAEQQLRQWETQAGFHYLLQSIYLNLSNSLQIRWLAVIQFKNGVDKYWRSTRINAIPKDEKASIRGRLFEMIDEQNNQLCIQNAQASARIARLDFPVEWPTLFEDLENLLNDEIIRKDSVKIYNILMHINQIVKVLGTARIGRCRPAMQSKVPLILPLIVRIYLQSFEEWTTSSNLN--YEDLSSLQVSYLALKVLRRIICEGYDRPQTDQSVCDFIKLSVSHFEMLISNHENFKKFDIYEKFIKCLGKLYFNLVTGSPANFILLPCSTQILITYTRLIFDKAPKVYRENSDVTGDFWEQTAIRGLLILKRVINFIHKKGAITLKARSDKLTIDASINKINTEFLNENLITRLVDTLMEWYLRLRPTELENWFMDPEEWINEQMAT-SYEYQIRPCAENVFQDLMNTFSELLVPYLLKKIEN-DASKLSNSLDDFLRKDAIYASFQLSASAVSEMVDFDRLLIQVFLPEATNTNISGDELRIIRRRVALIINEWSTVKCSEESKSLCYKLFTNFLTDEDDKVVLLTTVQTVRTMVDDWNFNKDTFQPFLTENVHLLLRKILPSVSLTETRLYVLNTLSDIIIQTKPLISRDLLVEILQIIPNLWEIATNNASEAILANALLRLLRNLVSSLGSQSHLTWDIAIPVVALACDPSSMQYQLLSEDGYELWGMLLQNFSSHDQEFDDKFVELVPFLKYGIETHTEILPTLLEIIKSYALILNPVDFFSNNTFQDIFKQMSKYLLKLREDSFQLVLEIWEILILSNESDYENLLLQKFYETGVLSALFDAIFLEEAPSSYLCSQIIQIIARISYVNPDALMTFLATYHDNLPTSNENARMPESIRKIVSKDQTYDSVVNKLLTGWIVCFRDIFDPKFKKVHILGISSLLRTGLVPILTEFSSIASLWIEMLEEIN--ETNRGDCEKYHLNDIVTEQSIAFHP-LTAEQLRYHQLCKNNDPVHNISLKDFISQSMEYLESHLGVERYQEFLKTINPSLLENLQMFLSIQPQEARP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . ::*** **:. : * * **:**:*****.**: :* .*: * : .:::*****: **:*:*:*** . :*:.::**:::*. *: ::* **:. * * *::**** * :** :* * :.: :*.:: :. *: : ::.*.*.: *:. * : . .. * : :: : : : . . ****: : *:*****:: :*: .*:.: .* .*:: ..::: ::. ..: . :: .. :: : *.* :*: : : * *. : . . ...** :*: :: : ::* ::: * : .:: * . . :**: *:. :*.: *:. *: * ** * *** : *: . *::*.:***:* :* *::: :.: *.* **: ::. :... :.:: :* ***:* :. *:* : : ****: : :*** : :. : :**** :*.:* :** ..: :. *: : *:* *:* ** : *. *:: ***::*..* * *:* :. ** ::* .*: :*:::**:.** :* :.: : * : ::* :* **: : :: :* *:* * :**..**::*: : : :**: *: * *. : * *** *** : *:* .. *: * :: *:*: . *. * * ::**:.* :: . * :. .: :.: : * :: :. **:: * : * :* :::: :*. :* .:: * . : * : ::.*: *.. : ::* .:: * *.::.::: *: : :* :*: :*: *.: *** :. * :*..* .: :* *.:: :.: :. * . * .:: . .:** : ::: :****.:**::** :.:: :. ** : :*.:::*::..:: :** **. ", "identical_positions": 248, "similar_positions": 377, "identity": "23.87%" }, { "cls_id": "homologset.agr.SGD:S000006047", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3U821-1", "uniprot_id": "WDR75_MOUSE", "id": "Q3U821-1", "name": "WD repeat-containing protein 75", "aln": "-----MVEEG-VRVVRCGGSRLN--------FRRAVFSVDSKYIFCVSGDFVKVYSTTTEECVHILHGHTDLVSG---------------------ILVNPSNHLQLYSCSFDGTIKLWDYVDGILIKT--FTIGPKLHAFFIPLHAEDSVFLTISKEEP---DIFQLVSVKLPKSTSQDVEARQLTFVLDYINRSPKCIAFGNEGEYVAAVRDFYLSVYFFKKK-------KTCNFTLPSTKNKKNAKNKFTCVACHPKEDCIASGHMDGKIRLWR---NFHSDQKYTYTCLHWHHDMVMDLAFTVTGTSLLSGGRECVLVEWRDGSEKNKEFLPRLGSSIEHISVSPAGDLFCTSHSDNKITVIHRN--------LDASAVIQGLVKDRSISTG-LMVDPRTKALVLNGKPGHLQFYSLQGDKQLYNLDIIQQEYINDEG---LTQTELTKAAFGCSGTWLATVEQRQENENELELQMKLWNYSKKTQGFVLNTKIAMPHDDHITA----LCFNNAESYEKPILVTASRDGHFKVWILTDDSD--IYKKAIAWTCDFVGSYHKYQATNCCFSEDGSLLAVSFEEIVTIWDS--------------------------------------------QTWELKCTFCQRAGK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IRHLCFGRLTCSKYLLGTTDNGILCCWNLLSCSIQWSAKLNVRVMEPDPYSDHVAAVAQSSAGSDLFVFKPSEPRPLYIQKNVSREEVQWGVFVPRDVPESFTSETHQWLNRSQFYFLTKSQSLLTFSTK-SPEEKLTPTSKQLLAEESLPTTPFSFILGKHRQQQGA-KLTETSENELVQLPLTENIPAITELLHTPAHVLPSASFLCSLFVNSLLLSKETKSAEEVPDDVDMEGN------------KESDDSDEEYDLTEKDKETNNNTDLGEDAIHQLSKSEEKELRKFRKVDYSWLTAL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K9A7-1", "uniprot_id": "A0A0G2K9A7_RAT", "id": "A0A0G2K9A7-1", "name": "WD repeat-containing protein 75", "aln": "-----MVEER-VRVVRCGGSRLN--------FRRAVFSVDSKYIFCVSGDFIKVYSTATEECVHILRGHKHVVSG---------------------ILINPNNHLQLYSCSFDGTIKLWDYLDGILIKT--FTVGPKLHALFIPAHAEDTVFLTINKEDP---DIFQLVSVKLPKSTSRNVEAKELTFVLDYINKSPKSIAFGNEGEYVAAVRDFYLSVYFLKKK-------KTCNFTLPSTKNKKNARNKFTCVACHPKEDCIASGHMDGKIRLWR---NFHDDKLYTYTCLHWHHDMVMDLAFTVTGTSLLSGGQECVLVEWRDGSEKNKEFLPRLGSAIEHISVSPAGDLFCTSHSDNKITVIHRN--------LDASAVIQGLVKDRSISTG-LMVDPRTKALVLNGKPGHLQFYSLQSDKQLYNLDIIQQEYINDQG---LIQIELTKAAFGCSGSWLATVEQRQENENELELQMKLWNYSKKTQGFVLNTKISMPHDDHITA----LCFNNAENYEKPILVTASRDGHFKVWVLTDDSD--IYKKAIGWTCDFVGSYHKYQATNCCFSEDGSLLAVSFEEIVTIWDS--------------------------------------------ETWELKCTFCQRAGK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IRHLCFGRLTCSKYLLGTTENNLLCCWNLLSCSMQWSAKLNVRVMEADPYSDHIAAVARSSEGSDLFVFKPSEPRPLYIQKNVSREKVQWGVFVPRDVPESFTSEAHQWLNRSQFYFLTESQCLLTFSTK-YAEEKLTPTSKQLLAEESLPTTPFSFILGKHRQQQDT-KSTETSESELVQLPLTENIPAITELLHTPAHVLPSASFLCTLFVNSLLLSKETKSAEEISDDVDMEGN------------EESDDSDEEYDLTEKAKETSN-PDLGEDAIHQLSKSEEKELRKFRKVDYSWLTAL---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IWA0-1", "uniprot_id": "WDR75_HUMAN", "id": "Q8IWA0-1", "name": "WD repeat-containing protein 75", "aln": "-----MVEEENIRVVRCGGSELN--------FRRAVFSADSKYIFCVSGDFVKVYSTVTEECVHILHGHRNLVTG---------------------IQLNPNNHLQLYSCSLDGTIKLWDYIDGILIKT--FIVGCKLHALFTLAQAEDSVFVIVNKEKP---DIFQLVSVKLPKSSSQEVEAKELSFVLDYINQSPKCIAFGNEGVYVAAVREFYLSVYFFKKK-------TTSRFTLSSSRNKKHAKNNFTCVACHPTEDCIASGHMDGKIRLWR---NFYDDKKYTYTCLHWHHDMVMDLAFSVTGTSLLSGGRESVLVEWRDATEKNKEFLPRLGATIEHISVSPAGDLFCTSHSDNKIIIIHRN--------LEASAVIQGLVKDRSIFTG-LMIDPRTKALVLNGKPGHLQFYSLQSDKQLYNLDIIQQEYINDYG---LIQIELTKAAFGCFGNWLATVEQRQEKETELELQMKLWMYNKKTQGFILNTKINMPHEDCITA----LCFCNAEKSEQPTLVTASKDGYFKVWILTDDSD--IYKKAVGWTCDFVGSYHKYQATNCCFSEDGSLLAVSFEEIVTIWDS--------------------------------------------VTWELKCTFCQRAGK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IRHLCFGRLTCSKYLLGATENGILCCWNLLSCALEWNAKLNVRVMEPDPNSENIAAISQSSVGSDLFVFKPSEPRPLYIQKGISREKVQWGVFVPRDVPESFTSEAYQWLNRSQFYFLTKSQSLLTFSTK-SPEEKLTPTSKQLLAEESLPTTPFYFILGKHRQQQDE-KLNETLENELVQLPLTENIPAISELLHTPAHVLPSAAFLCSMFVNSLLLSKETKSAKEIPEDVDMEEE------------KESEDSDEENDFTEKVQDTSN-TGLGEDIIHQLSKSEEKELRKFRKIDYSWIAAL---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVR1-1", "uniprot_id": "WDR75_DANRE", "id": "Q7ZVR1-1", "name": "WD repeat-containing protein 75", "aln": "-----MVEKTDIRVVRCGGSKIN--------FRPPIISHDSRFVLCVSGDSVKVYSTRTEEWLHNLQGHNNQVTG---------------------IAFNPANQLQVYSCSADGTVKLWDFIDGILIKT--FVIGYPLYSLYVSEKHEGVIFLIVSMVTDSNNESFQLVAVHLPKSAEQEVEAKELSTVASKISPNPSCTAFGRGGEFIAFSRHLQLNVYFFRKQ-------KTYSFSLKAT-DKKAGKNAFTCVACHPTDDCIASGHEDGKIRLWR---NFNHKKEYTYSTKHWHHDAVNHLCFTPEGSNLLSGGIESVLVQWQYGDMSKKEFLPRLGGSISHVSASADGQLFCTAHSDNKISIIESS--------FKVSGLIQGLVRGDAVSTD-LMIDPRSKALVLNGKPGHLQFYSLLRDKHLYNLDIVQQEYIYEAG---LDQFEVVKAVFDVKGSWLATVEERGHKTSDLEFFLKLWAFDETTQSFVLNTTVTEAHSERITS----MCFSSSE--ETTMLVTTALDGQFKAWCQTADAQ--QAQN--YWSCDFVGSYHNLKPKNCCFSADGSILAVSFQEVLTLWSP--------------------------------------------ETWELLTTLCQPPGE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IRDLCFGRLSCSKYLLSTTTKNLLCCWNLLTCALEWSTSVDVSRLQSDPLSENVAAFSFESKHTHLFVFKPSEPRPLFSQRYVCLERVDRAVFVPREEPFNSCDESCQWLNRSQLYFLTHNMDLLTFSSA-TEEDRMLSSSKRLVIDESVAVTPFYLLLGRHRKQQHK-LNTETQEP-ADKPQHTQGSVTIKQLLHTPAHVLPAASVLCSMFVRSLLISNTGVREEMDSSEQEMDSE------------KEEEESEEEMEACDGQQELRA-QGSVDEQKPKLSKAQERELKSLRKTDFSWMTSLIDSKP----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIG1-1", "uniprot_id": "Q9VIG1_DROME", "id": "Q9VIG1-1", "name": "", "aln": "---MNFDDEDRLELQFLAGGNIV--------EHAPVFSPDGRFMFVRCLTKVQVYATSTGELTRVLDDATAPLIS---------------------LELDLKQPDLLIGCTSTGELVRWNWRAGVLKKT--VSLTLGPGDTILTCHLMDLYKGGDTACAFVTAKGKAGEQVKWFVVNTSTGEKIDVNCGLKLKLRVPLVDVGKGQFKYIVLAQGFYIYFVNYETW-------TFCRY-------KSAKQHTITCVKMSPCEMVAATADSEGQIFVWR---DFEKKDSMTNTLFHWHHTEVTSLAFSPSGVSIYSGGHECVLVKWTVASPGYRKYLPRMSSVIRHIVVSDDNENVLVCTEDNAIQLISGSDNIIKSTVQHFTYETKDKTGQSKFPLG-LRLNPRTNTLVLNGRSGHLQFYSAYTKSLLYNLRVVDTNVHNEEANHIIYNTRITRAAFNIN--WMATGEVYNDLVNFAEVRLKFWHYNERLQSYILNTEIELPHENGFKA----IIFSNQFQVDNLRCATAGEDNVVKVWCITDSEN--IYKRGTMWSCLAQTSYRNLPIGSLCFSQDGSLLAVGYGNTLALYDARNPRLPLQTLSCPPGLDGVISKAQLRLAQTPLNGARKEFTQQRQQLWALLKTLLNSNDENLIQQAKDLIVGPPAKAKLVSEPDNTTKETVFKYIMKMPELGLHQKLQLLRRFGVECSVPLAHRQRLFQHLQQRAVIPQATKLRLRKLEFRLHRLHTRHRYKAKQRLSHVNNRRQKFENLVPQDVMNLFSVLKLDESSKPKKEKTGKCKLNGNSKPNTKAKKIPASAAPLQGLAQISHVQFG-AGDQAHLVAVCTESRVLIWNLLTLRLQAGLKLSVRQLAFDPLTNLMAVITKND---ELHVFQPNVPLPLYQRSNLP--KTHGLAWLPRRQPR-QSSINIDWQAQSTLLMLTHSQEIAYLALPGQSPSDDAPTPISFSQPAATDIILKHATFGIHVIKPQQ-ASGESLEKNGPLIVGREEHSAVNAFVNLSAHTMPAMSLICGEFVKSLLIPADSTSRHSSSAASDAALTNGVTVNGNGVGHQDSDGEHEDEELGEEARNTLDTRKTLLEQNEKLVDLPLEGETDLQGLDNRLRTITALRTKLRI-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02931-1", "uniprot_id": "UTP17_YEAST", "id": "Q02931-1", "name": "NET1-associated nuclear protein 1", "aln": "MTQSLGIEQYKLSVVSGGKPALNNLSSVTGNKNIARLSQDQRNYIIPFNNQIKVYSVETRQCVKTLKFANNSLLSGIFLQEEENNESIVKILLGDITVPQQEDAHLITVFTNNGHVIVLNYKGKLVESPKHFKISLADEKLANVFHSEGNYRILTTFKDPSQKAHNSLQSYRLYALTFDDAKKQFEVAHQAEWHNVILSNISSNGKLLAHMCKDVSTKDHEHKSISVVSLFDDSVNLSFPLGSILSSQTQSLSYNTRYVSSMAIDNMGQQLAVGFASGVISIVSLADLQIRLLKWHIDSVLSLSFSHDGSYLLSGGWEKVMSLWQLETNS-QQFLPRLNGIIIDCQVLGPQGNYYSLILQMTENNSNSD---YQFLLLNASDLTSKLSINGPLPVFNSTIKHIQQPISAMNTKNSNSITSLNHSKKKQSRKLIKSRRQDFTTN--VEINPINKNLYFPHISAVQIFDFYKNEQVNYQYLTSGVNNSMGKVRFELNLQDPIITDLKFTKDGQWMITYEIEYPPNDLLSSKDLTHILKFWTKNDNETNWNLKTKVINPHGISVPITKILPSPRSVNNSQGCLTADNNGGLKFWSFD----------------------------------------------SHESNWCLKKIS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPNFNHFSNSVSLAWSQDGSLIFHG--FDDKLQILDFDTFKKFESLENTKTVSEFTLDSEIQTVKLINDTN-LIVATRTTLNAINLLRGQVINSFDLYPFVNGVYKNGHMDRLITCDERTGNIALVINQQLTDLDGVPTINYKSRIIIFDSDLSTKLGNFTHHEYISWIGWNYDTDFIFLDIESTLGVVGTTVNTQLSDEVNNEGILDGLVSNTITTSASNSDIFAEQLHKLSSRG-----------KKSDTRDKNTNDNDEDEEDIALEFINGEKKDKLVNMN-SFTSMFDNIQNVQMDTFFDRVMKVLT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : : . : . . :* * : : ::**:. * : : * : . : : : : * : :: :: .. . : : . . : : : . .. . : :: . . : : . .: :** * *.*: * : *** * *: * :::***:.. * . . : . . : . . :. :.: . . .: * .. . ::. . : : : : : : . : . . : ** . :. : . : .* * . . : . . : ... . . *:.. : ::. . . *. . * . : : :: . : :. :: .: .. : ::: . : : : . : . . . : . : . .. :* . : . : . .: :: : :* . : . . :..: .:: : : .: : :* . : : ", "identical_positions": 34, "similar_positions": 193, "identity": "2.98%" }, { "cls_id": "homologset.agr.SGD:S000006048", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10922-1", "uniprot_id": "H10_MOUSE", "id": "P10922-1", "name": "Histone H1.0", "aln": "-MTENSTSAPAAK--------PKRAKASKKSTD-------------HPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHY-KVGENADSQIKLS--IKRLVTTGVLKQ---TKGVGASGSFRLAK----GDEPKRSVAFKKTKKEVKKVATPKKAAKPKKAASKAPSKKPKATPVKKAKKK--PAATPKKAKKPKVVKVK---------------PVKASKPKKA----------------KTVKPKAKSSAKRASKKK--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07305-1", "uniprot_id": "H10_HUMAN", "id": "P07305-1", "name": "Histone H1.0", "aln": "-MTENSTSAPAAK--------PKRAKASKKSTD-------------HPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHY-KVGENADSQIKLS--IKRLVTTGVLKQ---TKGVGASGSFRLAK----SDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKK--LAATPKKAKKPKTVKAK---------------PVKASKPKKA----------------KPVKPKAKSSAKRAGKKK--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43277-1", "uniprot_id": "H13_MOUSE", "id": "P43277-1", "name": "Histone H1.3", "aln": "-MSETAPAAPAAP--APVEKTPVKKKAKKTGAA--AGKRKA----SGPPVSELITKAVAASKERSGVSLAALKKALAAAG-YDVEKNNSRIKLG--LKSLVSKGTLVQ---TKGTGASGSFKLNK----KAASGEAKPKAKKAGAAKAKKPAGAAKKPKKATGAATPKKTAKKTPKKAKKPAAAAGAKKVSKSPKKVKAA--------------KPKKAAKSPAKAKAPKAKASKP-----KASKPK-ATKAKKAAPRKK-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16402-1", "uniprot_id": "H13_HUMAN", "id": "P16402-1", "name": "Histone H1.3", "aln": "-MSETAPLAPTIP--APAEKTPVKKKAKKAGAT--AGKRKA----SGPPVSELITKAVAASKERSGVSLAALKKALAAAG-YDVEKNNSRIKLG--LKSLVSKGTLVQ---TKGTGASGSFKLNK----KAASGEGKPKAKKAGAAKPRKPAGAAKKPKKVAGAATPKKSIKKTPKKVKKPATAAGTKKVAKSAKKVKTP--------------QPKKAAKSPAKAKAPKPKAAKP-----KSGKPK-VTKAKKAAPKKK-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P15864-1", "uniprot_id": "H12_MOUSE", "id": "P15864-1", "name": "Histone H1.2", "aln": "-MSEAAPAAPAAA--PPAEKAPAKKKAAKK-PA--GVRRKA----SGPPVSELITKAVAASKERSGVSLAALKKALAAAG-YDVEKNNSRIKLG--LKSLVSKGILVQ---TKGTGASGSFKLNK----KAASGEAKPQAKKAGAAKAKKPAGAAKKPKKATGAATPKKAAKKTPKKAKKPAAAAVTKKVAKSPKKAKVT--------------KPKK-VKSAS-------KAVKP-----KAAKPK-VAKAKKVAAKKK-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16403-1", "uniprot_id": "H12_HUMAN", "id": "P16403-1", "name": "Histone H1.2", "aln": "-MSETAPAAPAAA--PPAEKAPVKKKAAKK-AG--GTPRKA----SGPPVSELITKAVAASKERSGVSLAALKKALAAAG-YDVEKNNSRIKLG--LKSLVSKGTLVQ---TKGTGASGSFKLNK----KAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVA--------------KPKKAAKSAA-------KAVKP-----KAAKPK-VVKPKKAAPKKK-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43274-1", "uniprot_id": "H14_MOUSE", "id": "P43274-1", "name": "Histone H1.4", "aln": "-MSETAPAAPAAP--APAEKTPVKKKARKA-AG--GAKRKT----SGPPVSELITKAVAASKERSGVSLAALKKALAAAG-YDVEKNNSRIKLG--LKSLVSKGTLVQ---TKGTGASGSFKLNK----KAASGEAKPKAKRAGAAKAKKPAGAAKKPKKAAGTATAKKSTKKTPKKAKKPAAAAGAKK-AKSPKKAKAT--------------KAKKAPKSPAKAKTVKPKAAKP-----KTSKPK-AAKPKKTAAKKK-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10412-1", "uniprot_id": "H14_HUMAN", "id": "P10412-1", "name": "Histone H1.4", "aln": "-MSETAPAAPAAP--APAEKTPVKKKARKS-AG--AAKRKA----SGPPVSELITKAVAASKERSGVSLAALKKALAAAG-YDVEKNNSRIKLG--LKSLVSKGTLVQ---TKGTGASGSFKLNK----KAASGEAKPKAKKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKK-AKSPKKAKAA--------------KPKKAPKSPAKAKAVKPKAAKP-----KTAKPK-AAKPKKAAAKKK-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43276-1", "uniprot_id": "H15_MOUSE", "id": "P43276-1", "name": "Histone H1.5", "aln": "-MSETAPAETAAP--APVEKSPAKKKTTKKAG---AAKRKA----TGPPVSELITKAVSASKERGGVSLPALKKALAAGG-YDVEKNNSRIKLG--LKSLVSKGTLVQ---TKGTGASGSFKLNK----KAASGEAKPKAKKTGAAKAKKPAGAT--PKKPKKTAGAKKTVKKTPKKAKKPAAAG-VKKVAKSPKKAKAAA-------------KPKKAAKSPAKPKAVKSKASKPKVTKPKTAKPK-AAKAKKAVSKKK-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16401-1", "uniprot_id": "H15_HUMAN", "id": "P16401-1", "name": "Histone H1.5", "aln": "-MSETAPAETATP--APVEKSPAKKKATKKAAGAGAAKRKA----TGPPVSELITKAVAASKERNGLSLAALKKALAAGG-YDVEKNNSRIKLG--LKSLVSKGTLVQ---TKGTGASGSFKLNK----KAASGEAKPKAKKAGAAKAKKPAGAT--PKKAKKAAGAKKAVKKTPKKAKKPAAAG-VKKVAKSPKKAKAAA-------------KPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPK-AAKAKKAAAKKK-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43275-1", "uniprot_id": "H11_MOUSE", "id": "P43275-1", "name": "Histone H1.1", "aln": "-MSETAPVAQAAS--TATEKPAAAKKTKKP-AKAAAPRKKP----AGPSVSELIVQAVSSSKERSGVSLAALKKSLAAAG-YDVEKNNSRIKLG--LKSLVNKGTLVQ---TKGTGAAGSFKLNK----KAES-----KAITTKVSVKAKASGAAKKPKKTAGAAAKK--TVKTPKKPKKP---AVSKKTSKSPKKPKVV--------------KAKKVAKSPAKAKAVKPKASKA-----KVTKPKTPAKPKKAAPKKK-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07133-1", "uniprot_id": "H1T_MOUSE", "id": "Q07133-1", "name": "Histone H1t", "aln": "-MSETAPAASSTLVPAPVEKPSSKRRGKKPG---LAPARKP----RGFSVSKLIPEALSTSQERAGMSLAALKKALAAAG-YDVEKNNSRIKLA--LKRLVNKGVLVQ---TKGTGASGSFKLSK----KAASGNDKGKGKKSASAKAKK-------MGLPRASRSPK--SSKT-KAVKKP--KATPTKASGSGRKTKGA--------------KGVQQRKSPAKARAANPNSGKA-----KMVMQ--KTDLRKAAGRK--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22492-1", "uniprot_id": "H1T_HUMAN", "id": "P22492-1", "name": "Histone H1t", "aln": "-MSETVPAASASAGVAAMEKLPTKKRGRKPAGL-ISASRKV----PNLSVSKLITEALSVSQERVGMSLVALKKALAAAG-YDVEKNNSRIKLS--LKSLVNKGILVQ---TRGTGASGSFKLSK----KVIPKSTRSKAKKSVSAKTKK-------LVLSRDSKSPK--TAKTNKRAKKP--RATTPKTVRSGRKAKGA--------------KGKQQQKSPVKARAS-----KS-----KLTQHH-EVNVRKATSKK--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P02255-1", "uniprot_id": "H1_DROME", "id": "P02255-1", "name": "Histone H1", "aln": "-MSDSAVATSASPVAAPPATVEKKVVQKKASGSAGTKAKKASATPSHPPTQQMVDASIKNLKERGGSSLLAIKKYITATYKCDAQKLAPFIKKY--LKSAVVNGKLIQ---TKGKGASGSFKLSA----SAKKEKDPKAKSKVLSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAKAKDA-------------KKTGIIKSKPAATKAKVTAAKPKAVVAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4ABE3-1", "uniprot_id": "Q4ABE3_DROME", "id": "Q4ABE3-1", "name": "", "aln": "-MSDSAVATSASPVAAPPATVEKKVVQKKASGSAGTKAKKASATPSHPPTQQMVDASIKNLKEHGGSSLLAIKKYITATYKCDAQKLAPFIKKY--LKSAVVNGKLIQ---TKGKGASGSFKLSA----SAKKEKDPKAKSKVLSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAKAKDA-------------KKTGIIKSKPAATKAKVTAAKPKAVVAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4ABD8-1", "uniprot_id": "Q4ABD8_DROME", "id": "Q4ABD8-1", "name": "", "aln": "-MSDSAVATSASPVAAPPATVEKKVVQKKASGSAGTKAKKASATPSHPPTQQMVDASIKNLEERGGSSLLAIKKYITATYKCDAQKLAPFIKKY--LKSAVVNGKLIQ---TKGKGASGSFKLSA----SAKKEKDPKAKSKVLSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAKAKDA-------------KKTGIIKSKPAATKAKVTAAKPKAVVAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4AB54-1", "uniprot_id": "Q4AB54_DROME", "id": "Q4AB54-1", "name": "", "aln": "-MSDSAVATSASPVAAPPATVEKKVVQKKASGSAGTKAKKASATPSHPPTQQMVDASIKNLKERGGSSLLAIKKYITATYKCDAQKLAPFIKKY--LKSAVVNGKLIQ---TKGKGASGSFKLSA----SAKKEKDPKAKSKVLSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAKAKDA-------------KKTGIIKSKPAATKAKVTAAKPKAVIAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4AB94-1", "uniprot_id": "Q4AB94_DROME", "id": "Q4AB94-1", "name": "", "aln": "-MSDSAVATSASPVAAPPATVEKKVGQKKASGSAGTKAKKASATPSHPPTQQMGDASIKNLKERGGSSLLAIKKYITATYKCDAQKLAPFIKKY--LKSAVVNGKLIQ---TKGKGASGSFKLSA----SAKKEKDPKAKSKVLSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAKAKDA-------------KKTGIIKSKPAATKAKVTAAKPKAVIAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53551-1", "uniprot_id": "H1_YEAST", "id": "P53551-1", "name": "Histone H1", "aln": "-MAPKKSTTKTTSKGKKPATSKGKEKSTSKAAIKKTTAKKEE--ASSKSYRELIIEGLTALKERKGSSRPALKKFIKENYPIVGSASNFDLYFNNAIKKGVEAGDFEQ---PKGPAGAVKLAKKKSPEVKKEKEVSPKPKQAATSVSATASKAKAASTKLAPKKVVKKKSPTVTAKKASSPSSLTYKEMILKSMPQLNDGKGSSRIVLKKYVKDTFSSKLKTSSNFDYLFNSAIKKCVENGELVQPKGPSGIIKLNKKKVKLST---------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "D3ZEG0-1", "uniprot_id": "D3ZEG0_RAT", "id": "D3ZEG0-1", "name": "Histone H1.8", "aln": "MAPGSVSSVSSSSSVPSSDTSPPGSCGLPGAVSPDPSCSRIQVGQRNPTMLRMVLEALKAREKRQGTSVVAIKVYIQHKY-PTVGTTRFKYLLKQALETGMRRGLLTRPANSKAKGATGSFKLVP----KPKKKRTCAPKARGGATGTKETGSKESGLRKKDQVGKAKTEKAAPNPGRKRKAYPCSAATLEKAPKNAKAVPR----------EVREAPLKRDKAAGAPLTANIGQKVKHSGTGQEADAHGKTKDVCEKSKASASKVGPE----------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : .: ::: * * ::: : :: : * : : .:. ..: .: . : . ", "identical_positions": 3, "similar_positions": 28, "identity": "1.08%" }, { "cls_id": "homologset.agr.SGD:S000006050", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AM29-1", "uniprot_id": "AF9_MOUSE", "id": "A2AM29-1", "name": "Protein AF-9", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASSCAVQVKLELGHRAQVR---KKPTVEGFTHDWMVFVRGPEHSN---IQHFVEKVVFHLHESFP-RPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEP---------------------KKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKAGG-----------------DPNR-----------------------SIHTSSSS------------------------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSS-------------SSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKDSSKKPKENK-----------------------------------------PLKEEKIVPKMAFKEPKPMSKEPKADSNLLTV---TSGQQDKKAPSKRPPASDSEELSAKKRKKSSSEALFK------------------------------------------------------------------------------------SFSSAPPLILTCS-ADKKQIKDKSHVKMGKVKIESETSE--------------------------------------------------------------KKKSMLPPFDDIVDPNDSDVEENMSSKSDSEQPSPASSSSSSSSS----FTPSQTRQ-QGPLRSIMKDLHSDDNEEESDEAEDNDNDSEMERPVNRGGS-----------------RSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTN-NNQILEVKS-----------------------PIKQSKSDKQIKNGECDK---------------------------------------------------------------------------------------AYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITNTT-------------FDFDLCS-------LDKTTVRKLQSYLETSGTS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZRB6-1", "uniprot_id": "A0A8I5ZRB6_RAT", "id": "A0A8I5ZRB6-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASSCAVQVKLELGHRAQVR---KKPTVEGFTHDWMVFVRGPEHSN---IQHFVEKVVFHLHESFP-RPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEP---------------------KKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKAGG-----------------DPNR-----------------------SIHTSSSS------------------------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSS-------------SSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKDSSKKPKENK-----------------------------------------PLKEEKIVPKMAFKEPKPMSKEPKADSNLLTV---TSAQQDKKAPSKRPPVSDSEELSAKKRKKSSSEALFK------------------------------------------------------------------------------------SFSSAPPLILTCS-ADKKQIKDKSHVKMGKVKIESETSE--------------------------------------------------------------KKKSTLPPFDDIVDPNDSDVEENMSSKSDSEQPSPASSSSSSSSS----FTPSQTRQ-QGPLRSIMKDLHSDDNEEESDEAEDNDNDSEMERPVNRGGS-----------------RSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTN-NNQILEVKS-----------------------PIKQSKSDKQIKNGECDK---------------------------------------------------------------------------------------AYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITNTT-------------FDFDLCS-------LDKTTVRKLQSYLETSGTS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42568-1", "uniprot_id": "AF9_HUMAN", "id": "P42568-1", "name": "Protein AF-9", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASSCAVQVKLELGHRAQVR---KKPTVEGFTHDWMVFVRGPEHSN---IQHFVEKVVFHLHESFP-RPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEP---------------------RKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKAGG-----------------DPNR-----------------------SIHTSSSS------------------------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSS-------------SSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENK-----------------------------------------PLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTI---TSGQ-DKKAPSKRPPISDSEELSAKKRKKSSSEALFK------------------------------------------------------------------------------------SFSSAPPLILTCS-ADKKQIKDKSHVKMGKVKIESETSE--------------------------------------------------------------KKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSS----FTPSQTRQ-QGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGS-----------------RSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTN-NNQILEVKS-----------------------PIKQSKSDKQIKNGECDK---------------------------------------------------------------------------------------AYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITNTT-------------FDFDLCS-------LDKTTVRKLQSYLETSGTS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BAV5-1", "uniprot_id": "A0A8M3BAV5_DANRE", "id": "A0A8M3BAV5-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASSGAVQVKLELGHRAQVR---KKPTVEGFTHDWMVFVRGPEHSN---IQHFVEKVVFHLHESFP-RPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEP---------------------KKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEEFRRKLLKAGGQ---------------RDPHKRSSEDSKVMVMQEGSTSLFGPHLKLPTLPSS------------------------SLTLTFSDAKKSKSFPGSKDGSKSSSALTT-------------TNNISSSSLKLHKPPKDHKDHKDKPSKDSKESKSAFRDFSKDSGKLSKDS-KKPKENQ-----------------------------------------PIQEDRPIPQMGFKEPKSTSKEQRS-SELSFS---SLGQ------SKRRPVLDNEGHVTKKRKSSFSESSQK------------------------------------------------------------------------------------QQACPALLQQQHHHSDKKVLKDKPQIRHNRLQNSELSEK--------------------------------------------------------------KKLQALPPFQDVLDPNDSDMDDNTFTRSDSDQPSPASSSSSSSSG----FGRGHKRQVLGPLRSVIPDLHSDENEEDSEEDDDNDMDSDLERPVHTQMTH----------------RHRRVSLSDGSESENSSGSSPLPHNDPPPLLKNS-SNQ-IEVKG-----------------------PIKQAKMDK-NKNIDCDK---------------------------------------------------------------------------------------AYLDELVELHRRLMALRERHILQQIVNLIEETGHFHITNTT-------------FDFDLCS-------LDKTTVRKLQSYLETTGSS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03111-1", "uniprot_id": "ENL_HUMAN", "id": "Q03111-1", "name": "Protein ENL", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDNQCTVQVRLELGHRAQLR---KKPTTEGFTHDWMVFVRGPEQCD---IQHFVEKVVFWLHDSFP-KPRRVCKEPPYKVEESGYAGFIMPIEVHFKNKEEP---------------------RKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRYKLLRAGG------------------------------------------VMVMPEGADT------------------------VSRPSPDYPMLPTIPLSAFSDPKKTKPSHG-------------SKDANKESSKTSKPHKVTKEHRERPRKDS-ESKSSSKELEREQAKSSKDTSRKLGEGRL----------------------------------------PKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRS------------------------------------------------------------------------------------APGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPRE--------------------------------------------------------------AKK--------ALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHS-QGPLRSMVEDLQSEESDED-------DSSSGEEAAGKTNPG-----------------RDSRLSFSD-SESDNSADSSLPSREPPPPQKPPPPNSKVSGRRS-----------------------PESCSKPEKILKKGTYDK---------------------------------------------------------------------------------------AYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTT-------------FDFDLFS-------LDETTVRKLQSCLEAVAT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0R462-1", "uniprot_id": "M0R462_RAT", "id": "M0R462-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDNQCTVQVKLELGHRAQLR---KKPTTEGFTHDWMVFVRGPEQCD---IQHFVEKVIFRLHDSFP-KPKRVCKEPPYKVEESGYAGFIMLIEVYFKNKEEP---------------------RKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRCKLLMAGG------------------------------------------VMVMPEGADT------------------------VSRPSPDYPMLPTIPLSAFSDPKKNKPSHG-------------SKDANKESGKASKPHKVAREHRERPRKDS-ESRSCSKEPERE-PKSAKDAARKL---------------------------------------------PKEEKAPVPKAAFKEPKMALKETKLESLSPKG--VSQPPTLPKASSKRPAATDSPKPSAKKPKKSGSKGARR------------------------------------------------------------------------------------APGTSPRAS---SFPDKKVARDKSS-KGDKGKMESEPRE--------------------------------------------------------------AKR--------TLQAEDSNSEDEASFRSESAQSSPAHASSSSDSSSDSDFEPSQNHS-QGPLRSMVEDLQSEGSDED-------DSSSGEESTVKTNPG-----------------RESRLSFSD-SESDNSADSCLPGREPLPPQKPPPPSSKVTGRRS-----------------------PEPCSKPEKILKKATYDK---------------------------------------------------------------------------------------AYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTT-------------FDFDLFS-------LDESTVRKLQSCLEAVAT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0B4KG69-1", "uniprot_id": "A0A0B4KG69_DROME", "id": "A0A0B4KG69-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAVKVQFEIGHTSKLRS-KKTPHPQAFTHDWEIYVQGVNKAD---ISAFVEKVVFVLHESFP-KPKRVVKEPPYAIQESGYAGFLLPVEIYFRNRDEP---------------------KRIVYQYDLVLQSTG-PPQHHVEVKTHIFEAPSEEFRTKLMRGGGVPVFGANIGAGSLARTLSPSVGSGETAHSNEMSGVKAKGVPGTISMNSDLNTGKKHKSRSEDPGKSNAFSALFGPPITKTSVTANNMAQVPVSKHSPEAKSAAVGGKG---VFHEGREKASKDRDKSSGGDKPREKDKKDRHGRDKDRKSSKSGDGKHERDKEKSKKDKSRDKEREREQGSGNTTSANALTVATSVGTAGGL----------------VKHTASPKPGKPNEMGAPSPKKTANDSAAGAVAPTSRSKERDEHKSVKSESKDKERSSSKKSKKDKKDKDKQRDESKDKRMPKDERPGQSDSPASGNLQSAHLQQQSQVASTGKATPTSVGSNSSSSMVSNIGKQKEEATGKHSEKAAESKGDKSTSNGNATDTKKSHKHKKKEKSKDKEKERNDRDKDKDKERDKDKLKEREKDKQHVTGSEKSSTVDPSPKLEGASPATEGGAPDKTPVSASASSGSKKEKHKKSKEKSSGKDEKRQREAVDKQADTKHTGKSQQSQSGQSKTPSNLDLSDMDSAQSAPDLAATNALAAAAAATLQHSDSSNSSFPDLPARSSSQQKPTKGNTGSGKETKSTVK------EHKGKSKQNDKTLEKNTDKTEKPDKTPDPKVDKSEKSEKEDKKRNRRSSQSSNSGSGAGVTGAFIEP-PVKASKKEQGKAAGEKSKSPSLRPPRETNSTGTGGGTPNAG---------AGFLAPPSSSPSNNHSAAVAASLNNNNNNNNNNTNSNSSHSPGEMTTPGQLQLPTEYLSELQELHHKIMTLQDNEELQHVVEMIAATGCYEITHKT-------------FDFDLCK-------LDRGTVQRLQEFLATSVSXHSLTSATGPALYS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35189-1", "uniprot_id": "TAF14_YEAST", "id": "P35189-1", "name": "Transcription initiation factor TFIID subunit 14", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVATVKRTIRIKTQQHILP-EVPPVENFPVRQWSIEIVLLDDEGKEIPATIFDKVIYHLHPTFA-NPNRTFTDPPFRIEEQGWGGFPLDISVFLLEKAGE---------------------RKIPHDLNFLQESYEVEHVIQIPLNKPLLT-------EELAKSGS-----------------------------------------------------------------------------------------------------------------------TEETTANTGTIGK------------------------------------------------------------------------------------------------------------------------------------RRTTTNTTAEPKAKRAKTGSASTVKG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVDLEKLA--------------------------FGLTKLNEDDLVGVVQMVTDNKTPEMNVTN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------NVEEGE-------------FIIDLYS-------LPEGLLKSLWDYVKKNTE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9ULM3-1", "uniprot_id": "YETS2_HUMAN", "id": "Q9ULM3-1", "name": "YEATS domain-containing protein 2", "aln": "MSGIKRTIKETDPDYEDVSVALPNKRHKAIENSARDAAVQKIETIIKEQFALEMKNKEHEIEVIDQRLIEARRMMDKLRACIVANYYASAGLLKVSEGSKTCDTMVFNHPAIKKFLESPSRSSSPANQRAETPSANHSESDSLSQHNDFLSDKDNNSNMDIEERLSNNMEQRPSRNTGRDTSRITGSHKTEQRNADLTDETSRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWMVYVRGSRREPS--INHFVKKVWFFLHPSYKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKDSQNKRIDIIHNLKLDRTYTGLQTLGAETVVDVELHRHSLGEDCIYPQSSESDISDAPPSLPLTIPAPVKASSPIKQSHEPVPDTSVEKGFPASTEAERHTPFYALPSSLERTPTKMTTSQKVTFCSHGNSAFQPIASSCKIVPQSQVPNPESPGKSFQPITMSCKIVSGSPISTPSPSPLPRTPTSTPVHVKQGTAGSVINNPYVIMDKQPGQVIGATTPSTGSPTNKISTASQVSQGTGSPVPKIHGSSFVTSTVKQEDSLFASMPPLCPIGSHPKVQSPKPITGGLGAFTKVIIKQEPGEAPHVPATGAASQSPLPQYVTVKGGHMIAVSPQKQVITPGEGIAQSAKVQPSKVVGVPVGSALPSTVKQAVAISGGQILVAKASSSVSKAVGPKQVVTQGVAKAIVSGGGGTIVAQPVQTLTKAQVTAAGPQKSGSQGSVMATLQLPATNLANLANLPPGTKLYLTTNSKNPSGKGKLLLIPQGAILRATNNANLQSGSAASGGSGAGGGGGGGGGGGSGSGGGGSTGGGGGTAGGGTQSTAGPGGISQHLTYTSYILKQTPQGTFLVGQPSPQTSGKQLTTGSVVQGTLGVSTSSAQGQQTLKVISGQKTTLFTQAAHGGQASLMKISDSTLKTVPATSQLSKPGTTMLRVAGGVITTATSPAVALSANGPAQQSEGMAPVSSSTVSSVTKTSGQQQVCVSQATVGTCKAATPTVVSATSLVPTPNPISGKATVSGLLKIHSSQSSPQQAVLTIPSQLKPLSVNTSGGVQTILMPVNKVVQSFSTSKPPAILPVAAPTPVVPSSAPAAVAKVKTEPETPGPSCLSQEGQTAVKTEESSELGNYVIKIDHLETIQQLLTAVVKKIPLITAKSEDASCFSAKSVEQYYGWNIGKRRAAEWQRAMTMRKVLQEILEKNPRFHHLTPLKTKHIAHWCRCHGYTPPDPESLRNDGDSIEDVLTQIDSEPECPSSFSSADNLCRKLEDLQQFQKREPENEEEVDILSLSEPVKINIKKEQEEKQEEVKFYLPPTPGSEFIGDVTQKIGITLQPVALHRNVYASVVEDMILKATEQLVNDILRQALAVGYQTASHNRIPKEITVSNIHQAICNIPFLDFLTNKHMGILNEDQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : : : : .:.* : : :..** : ** :: . :**: : . *:. * : :.:.: : . :: . :. . . : : : : : . . . . . . : :: . : * . : ", "identical_positions": 11, "similar_positions": 56, "identity": "0.77%" }, { "cls_id": "homologset.agr.SGD:S000006052", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09895-1", "uniprot_id": "RL5_RAT", "id": "P09895-1", "name": "Large ribosomal subunit protein uL18", "aln": "MGFVKVVKNKAYFKRYQVRFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYEGQVEVNGDEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNNVTPDMMEEMYKKAHAAIRENPVYEKKPKR------EVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAAES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47962-1", "uniprot_id": "RL5_MOUSE", "id": "P47962-1", "name": "Large ribosomal subunit protein uL18", "aln": "MGFVKVVKNKAYFKRYQVRFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYEGQVEVNGGEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNNVTPDMMEEMYKKAHAAIRENPVYEKKPKR------EVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAAES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46777-1", "uniprot_id": "RL5_HUMAN", "id": "P46777-1", "name": "Large ribosomal subunit protein uL18", "aln": "MGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNSVTPDMMEEMYKKAHAAIRENPVYEKKPKK------EVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAAES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W5R8-1", "uniprot_id": "RL5_DROME", "id": "Q9W5R8-1", "name": "Large ribosomal subunit protein uL18", "aln": "MGFVKVVKNKQYFKRYQVKFRRRREGKTDYYARKRLTFQDKNKYNTPKYRLIVRLSNKDITVQIAYARIEGDRVVCAAYSHELPKYGIQVGLTNYAAAYCTGLLVARRVLNKLGLDSLYAGCTEVTGEEFNVEPVDDGPGAFRCFLDVGLARTTTGARVFGAMKGAVDGGLNIPHSVKRFPGYSAETKSFNADVHRAHIFGQHVADYMRSLEEEDEESFKRQFSRYIKLGIRADDLEDIYKKAHQAIRNDPTHKVTAKKS----SAVTKKRWNAKKLTNEQRKTKIAAHKAAYVAKLQSETEA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P26321-1", "uniprot_id": "RL5_YEAST", "id": "P26321-1", "name": "Large ribosomal subunit protein uL18", "aln": "MAFQKDAKSSAYSSRFQTPFRRRREGKTDYYQRKRLVTQHKAKYNTPKYRLVVRFTNKDIICQIISSTITGDVVLAAAYSHELPRYGITHGLTNWAAAYATGLLIARRTLQKLGLDETYKGVEEVEGEYELTEAVEDGPRPFKVFLDIGLQRTTTGARVFGALKGASDGGLYVPHSENRFPGWDFETEEIDPELLRSYIFGGHVSQYMEELADDDEERFSELFKGYLADDIDADSLEDIYTSAHEAIRADPAFKPTEKKFTKEQYAAESKKYRQTKLSKEERAARVAAKIAALAGQQ------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.* * .*.. * .*:*. ************ ****. *.* ********::**.:*:** ** : * ** ::.***:****:**: ****:****.****:*** *:::*:*. * * ** * .*.::. * .* :** ** ***** :****:*** **** :*** :****:. *::.::.:: * :*:* :*::**. * ::**: :.. *. *: .: .* :*::*..** *** :*..: . *: . .*::. *:: :: ::* : *: ", "identical_positions": 131, "similar_positions": 91, "identity": "43.23%" }, { "cls_id": "homologset.agr.SGD:S000006053", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZNJ0-1", "uniprot_id": "D3ZNJ0_RAT", "id": "D3ZNJ0-1", "name": "Cytochrome c oxidase assembly protein COX11, mitochondrial", "aln": "MGGLWCPGWRFITLCGRGWSQPRWSGRTVVNAERALRPGWNGVGGAEQGLRRLGTWKRPSG-ARGPVAQPPRRPKSSNPFQRAQEDEWRRRNKTVLTYVAAAAVGMLGASYAAVPLYRLYCQVGRDEARHGSHLSHHSVPEAEVTHPWSPRFQTGKDVPKTTGLGGSAVAGHASDQIENMVPVK-DRIIKVTFNADVHASLQWNFRPQQTEIYVVPGETALAFYKAKNPTDKPVIGISTYNVVPFEAGQYFNKIQCFCFEEQRLNPQEEVDMPVFFYIDPEFAEDPRMVNVDLITLSYTFFEAKEGHKLAVPGYN---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P8I6-1", "uniprot_id": "COX11_MOUSE", "id": "Q6P8I6-1", "name": "Cytochrome c oxidase assembly protein COX11, mitochondrial", "aln": "MGGLWCPGWRLVASCGRGWRQPGWSGRTVVNAELVLRPGWDGLGGAERGLRRLGTWKRPCG-VRGPATQPPRRPRSSNPFQRAQEDEWRRRNKTVLTYVAAAAVGMLGASYAAVPLYRLYCQT--------------------------------------TGLGGSAVAGHSSDQIENMVPVK-DRVIKVTFNADVHASLQWNFRPQQTEIYVVPGETALAFYKAKNPTDKPVIGISTYNVVPFEAGQYFNKIQCFCFEEQRLNPQEEVDMPVFFYIDPEFAEDPRMVNVDLITLSYTFFEAKEGHKLPVPGYN---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6N1-1", "uniprot_id": "COX11_HUMAN", "id": "Q9Y6N1-1", "name": "Cytochrome c oxidase assembly protein COX11, mitochondrial", "aln": "MGGLWRPGWRCVPFCGWRWIHPGSPTRAAERVEPFLRPEWSGTGGAERGLRWLGTWKRCSLRARHPALQPPRRPKSSNPFTRAQEEERRRQNKTTLTYVAAVAVGMLGASYAAVPLYRLYCQT--------------------------------------TGLGGSAVAGHASDKIENMVPVK-DRIIKISFNADVHASLQWNFRPQQTEIYVVPGETALAFYRAKNPTDKPVIGISTYNIVPFEAGQYFNKIQCFCFEEQRLNPQEEVDMPVFFYIDPEFAEDPRMIKVDLITLSYTFFEAKEGHKLPVPGYN---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VMQ6-1", "uniprot_id": "Q9VMQ6_DROME", "id": "Q9VMQ6-1", "name": "Cytochrome c oxidase assembly protein COX11, mitochondrial", "aln": "---------MMRSLCALRG-----------QCQQLFRSSIRPQNSVHK-------------------SQQFWRMKSTD---SPEDAARKLRAKSTLYYITAGGVLIVGLSYAAVPLYSIFCQA--------------------------------------YSYGGTTTQGHDAEKVEHMKKIE-DRVLKIRFNADIGSSMRWNFKPQQYEIKVAPGETALAFYTARNPTDKPVIGISTYNVIPFEAGAYFNKIQCFCFEEQQLNPHEEVDMPVFFYIDPEITADPALETCDTITLSYTFFEAKEGLKLNFPSYAKPHAASA--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P19516-1", "uniprot_id": "COX11_YEAST", "id": "P19516-1", "name": "Cytochrome c oxidase assembly protein COX11, mitochondrial", "aln": "----------MIRICPIVRSKVPLLGTFLRSDSWLAPHALALRRAICKNVALRSYSVNSEQPKHTFDISKLTRNEIQQLRELKRARERKFKDRTVAFYFSSVAVLFLGLAYAAVPLYRAICAR--------------------------------------TGFGGIPITDRRKFTDDKLIPVDTEKRIRISFTSEVSQILPWKFVPQQREVYVLPGETALAFYKAKNYSDKDIIGMATYSIAPGEAAQYFNKIQCFCFEEQKLAAGEEIDMPVFFFIDPDFASDPAMRNIDDIILHYTFFRAHYGDGTAVSDSKKEPEMNADEKAASLANAAILSPEVIDTRKDNSN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . : . * . : . : : ::. *.:: .* ::* :******* * . ** . .: ::: :. :: ::: *.::: : *:* *** *: * ********* *:* :** :**::**.: * **. *************:* . **:******:***::: ** : . * * * ****.*: * ... ", "identical_positions": 79, "similar_positions": 62, "identity": "22.7%" }, { "cls_id": "homologset.agr.SGD:S000006055", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99JD3-1", "uniprot_id": "ODC_RAT", "id": "Q99JD3-1", "name": "Mitochondrial 2-oxodicarboxylate carrier", "aln": "MSAS--NVSLLHETCRQVAAGGCAGLVEICLMHPLDVVKTRFQVQRSVTD----------PQSYKSLRDSFQVIFRTEGLFGFYKGIIPPILAETPKRAVKFSTFELYKKFLGYMSLSPG-----LTFPIAGLGSGLTEAVVVNPFEVVKVGLQVNRNMFTEQPSTFAYARQIIKKEGWGFQGLNKGFTATLGRHGIFNMTYFGFYYNVKDNIPSSKDPTLEFLRKFGIGFVSGTVGSVFNIPFDVAKSRIQGPQPVPGEIKYRGCFKTMETVYREEGILALYKGLLPKVMRLGPGGGVMLLVYEYTYAWLQENW-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZ09-1", "uniprot_id": "ODC_MOUSE", "id": "Q8BZ09-1", "name": "Mitochondrial 2-oxodicarboxylate carrier", "aln": "MSAS--NVSLLHETSRQVAAGGSAGLVEICLMHPLDVVKTRFQVQRSVTD----------PQSYRTVRGSFQMIFRTEGLFGFYKGIIPPILAETPKRAVKFSTFELYKKFLGYMSLSPG-----LTFLIAGLGSGLTEAVVVNPFEVVKVGLQVNRNLFKEQPSTFAYARQIIKKEGLGFQGLNKGLTATLGRHGIFNMVYFGFYHNVKNIIPSSKDPTLEFLRKFGIGFVSGTMGSVFNIPFDVAKSRIQGPQPVPGEIKYRSCFKTMEMIYREEGILALYKGLVPKVMRLGPGGGVMLLVYEYTYAWLQENW-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQT8-1", "uniprot_id": "ODC_HUMAN", "id": "Q9BQT8-1", "name": "Mitochondrial 2-oxodicarboxylate carrier", "aln": "MSAKP-EVSLVREASRQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATD----------PNSYKSLVDSFRMIFQMEGLFGFYKGILPPILAETPKRAVKFFTFEQYKKLLGYVSLSPA-----LTFAIAGLGSGLTEAIVVNPFEVVKVGLQANRNTFAEQPSTVGYARQIIKKEGWGLQGLNKGLTATLGRHGVFNMVYFGFYYNVKNMIPVNKDPILEFWRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAVMLLVYEYTYSWLQENW-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3T2-1", "uniprot_id": "Q9V3T2_DROME", "id": "Q9V3T2-1", "name": "Mitochondrial 2-oxodicarboxylate carrier", "aln": "MAGQQHDISHAKRAAFQVLAGGSAGFLEVCIMQPLDVVKTRIQIQATPAPN----AAALGEVHYNGVFDCFAKMYRHEGISSYWKGIMPPILAETPKRAIKFLVFEQTKPLFQFGSPTPTP----LTFSLAGLTAGTLEAIAVNPFEVVKVAQQADR--QKKMLSTFAVAKGIIQQDGLGFSGLNKGITATMGRNGVFNMVYFGFYHSVKNVVPEYKESHLEFLRKVTIGFLAGTLACFVNIPFDVAKSRIQGPQPVPGQIKYRGTLSSMGIVYREEGFRALYKGLVPKIMRLGPGGAILLLVFEYSYDYLLHNYS----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLF1-1", "uniprot_id": "Q9VLF1_DROME", "id": "Q9VLF1-1", "name": "Mitochondrial 2-oxodicarboxylate carrier", "aln": "MATRS-EETVRSLAHWQFLAGGLSGFIEIICFHPLDVVKTRMQIQGAHPFG--------GEVVYTCPLDAIVKIYRYEGLSSLWKGIVPPICVETPKRGGKFLMYESLKPYFQFGAPQPTP----LTHAMSGSMAAILESFLVNPFEVVKITQQAHR---GKRLKTLSVVKYIIKHDGYGIKGLYRGITALVARNAVFHFGFFGFYNALKDIVPSPEDKTYNILRKVIIAGLASSLACVMSVTLDMAKCRIQGPQPVKGEVKYQWTISTIKSTFKEEGFRSLFKGLGAMILRVGPGGAMLLVTYEYLFEFLKSQNI----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03028-1", "uniprot_id": "ODC1_YEAST", "id": "Q03028-1", "name": "Mitochondrial 2-oxodicarboxylate carrier 1", "aln": "MTSID---NRPLPFIYQFTAGAIAGVSELLVMYPLDVVKTRMQLQVTTKGHPAVVAAKAAVDHYTGVMDCLTKIVKKEGFSHLYKGITSPILMEAPKRAIKFSGNDTFQTFYKKIFPTPNGEMTQKIAIYSGASAGAVEAFVVAPFELVKIRLQDVN---SQFKTPIEVVKNSVVKG--GVLSLFNGLEATIWRHVLWNAGYFGIIFQIRKLLPAAKTSTEKTRNDLIAGAIGGTVGCLLNTPFDVVKSRIQ--RSSGPLRKYNWSLPSVLLVYREEGFKALYKGFAPKVMRLAPGGGLLLVVFTNVMDFFREVKYGKKQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . *. **. :*. *: : ********:*:* * ..: : : **: :*** .** *:***. ** : : * :* :. *:. * ***:**: * . : ... .: : : *. .* .*: * : *: ::: :**: ::. :* : : ... . :..::..... .:*:.*.*** :. **. : :: ::***: :*:**: . ::*:.***.::*:.: :: ", "identical_positions": 66, "similar_positions": 99, "identity": "20.62%" }, { "cls_id": "homologset.agr.SGD:S000006056", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RZ79-1", "uniprot_id": "B2RZ79_RAT", "id": "B2RZ79-1", "name": "Iron-sulfur cluster assembly enzyme ISCU", "aln": "-MAAAGAGRLRRAASALLLRSPRLPARELSAPARLYHKKVVDHYENPRNVGSLDKTSKNVGTGLVGAPACGDVMKLQIQVDE-KGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTIKNTDIAKELCLPPVKLHCSMLAEDAIKAALADYKLKQEAKKDEPEKQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D7P6-1", "uniprot_id": "ISCU_MOUSE", "id": "Q9D7P6-1", "name": "Iron-sulfur cluster assembly enzyme ISCU", "aln": "MAAATGAGRLRRAASALLLRSPRLPARELSAPARLYHKKVVDHYENPRNVGSLDKTSKNVGTGLVGAPACGDVMKLQIQVDE-KGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTIKNTDIAKELCLPPVKLHCSMLAEDAIKAALADYKLKQESKKEEPEKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1K1-1", "uniprot_id": "ISCU_HUMAN", "id": "Q9H1K1-1", "name": "Iron-sulfur cluster assembly enzyme ISCU", "aln": "-MAAAGAFRLRRAASALLLRSPRLPARELSAPARLYHKKVVDHYENPRNVGSLDKTSKNVGTGLVGAPACGDVMKLQIQVDE-KGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTIKNTDIAKELCLPPVKLHCSMLAEDAIKAALADYKLKQEPKKGEAEKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHK6-1", "uniprot_id": "ISCU_DROME", "id": "Q9VHK6-1", "name": "Iron-sulfur cluster assembly enzyme IscU", "aln": "-------MSLVRNSSR-LLRS--QLKRVQSVPVALYHENVVEHYENPRNVGSLDKKDVTVGTGLVGAPACGDVMKLQIKVDE-NGKIVDAKFKTFGCGSAIASSSLATEWVKGKSIDEAGKLKNTDIAKELRLPPVKLHCSMLAEDAIKAALADYKVKQQKKVAN----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03020-1", "uniprot_id": "ISU1_YEAST", "id": "Q03020-1", "name": "Iron sulfur cluster assembly protein 1, mitochondrial", "aln": "-MLPVITRFARPALMAIRPVNAMGVLRASSITKRLYHPKVIEHYTHPRNVGSLDKKLPNVGTGLVGAPACGDVMRLQIKVNDSTGVIEDVKFKTFGCGSAIASSSYMTELVQGMTLDDAAKIKNTEIAKELSLPPVKLHCSMLAEDAIKAAIKDYKSKRNTPTMLS---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * . *** :*::** :*********. .***************:***:*:: .* * *.:************** ** *:* ::::* .:***:***** *******************: *** *:: ", "identical_positions": 89, "similar_positions": 26, "identity": "52.66%" }, { "cls_id": "homologset.agr.SGD:S000006059", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7EKZ5-1", "uniprot_id": "F7EKZ5_RAT", "id": "F7EKZ5-1", "name": "CXXC-type zinc finger protein 1", "aln": "----------------------------------MEGDGSDLEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRHKKCRERDGSERDGSEPRDEGGGRKRPASDPELQRRAGSGTGVGAMLARGSASPHKSSPQPLVATPSQHHQQQQQQQQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSEALPRPRRPPPTQQQPQQSQKLGRIREDEGTVLSSVVKEPPEATATPEPLSDEDLALDPDLYQDFCAGAFDDH-VPWMSDAEESPFLDPALRKRAVKVKHVKRREKKSEKKVMERKEERYKRHRQKQKHKDKWKHPERADAKDPASLPQCLGPGCVRAAQPGSKYCSDDCG--MKLAANRIYEILPQRIQQWQQSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILRAKQQAVREDEENNENDSDDTDLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYPTRIEGATRLFCDVYNPQSKTYCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELTGDFCRLPKRQCNRHYCWEKLRRAEVDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALMLHQTIQHDPLTTDLRSSADR---------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWW7-1", "uniprot_id": "CXXC1_MOUSE", "id": "Q9CWW7-1", "name": "CXXC-type zinc finger protein 1", "aln": "----------------------------------MEGDGSDLEPPDAGDDSKSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRHKKCRERDGSERAGSEPRDEGGGRKRPASDPELQRRAGSGTGVGAMLARGSASPHKSSPQPLVATPSQHHHQQQQQQQQQ-IKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSEALPRPRRPPPTQQQPQQSQKLGRIREDEGTVLSSVVKEPPEATATPEPLSDEDLALDPDLYQDFCAGAFDDHGLPWMSDAEESPFLDPALRKRAVKVKHVKRREKKSEK----KKEERYKRHRQKQKHKDKWKHPERADAKDPASLPQCLGPGCVRAAQPGSKYCSDDCG--MKLAANRIYEILPQRIQQWQQSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILRAKQQAVREDEENNENDSDDTDLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYPTRIEGATRLFCDVYNPQSKTYCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELTGDFCRLPKRQCNRHYCWEKLRRAEVDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALMLHQTIQHDPLTTDLRSSADR---------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P0U4-1", "uniprot_id": "CXXC1_HUMAN", "id": "Q9P0U4-1", "name": "CXXC-type zinc finger protein 1", "aln": "----------------------------------MEGDGSDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRHKKSRERDGNERDSSEPRDEGGGRKRPVPDPDLQRRAGSGTGVGAMLARGSASPHKSSPQPLVATPSQHHQQQQQQ-----IKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSESLPRPRRPLPTQQQPQPSQKLGRIREDEGAVASSTVKEPPEATATPEPLSDEDLPLDPDLYQDFCAGAFDDHGLPWMSDTEESPFLDPALRKRAVKVKHVKRREKKSEK----KKEERYKRHRQKQKHKDKWKHPERADAKDPASLPQCLGPGCVRPAQPSSKYCSDDCG--MKLAANRIYEILPQRIQQWQQSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILRAKQQAVREDEESNEGDSDDTDLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYPTRIEGATRLFCDVYNPQSKTYCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELTGDFCRLPKRQCNRHYCWEKLRRAEVDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALMLHQTIQHDPLTTDLRSSADR---------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W352-1", "uniprot_id": "CXXC1_DROME", "id": "Q9W352-1", "name": "CXXC-type zinc finger protein 1", "aln": "MTDKRKYKKTVSFTRCTAIIFLTTKEVSKQKEEIRREIAREFDLPERKSKIATILKQEDQAYCICRSSDCSRFMIGCDGCEEWYHGDCIGITEKEAKHIKQYYCRRCKKENPELQTIFRLVATERAAASNAASTSLNAPG---------------VGPSGAAPAAAPVASATTSQQAPPPTTAAAKRKNSSAREP-------KMGKRCGTCEGCRR-PNCNQCDACRVRVGH------KPRCIFRTCVVQAATVLK--------------------------ESQATQAGPSRKREKAAPKSRNVQVGPRAASP----------------EIFLNPELQG--------------------------------------------------------------------------IRQCYGPNCCSHARPQSKYCSDKCG--FNLATKRIFQVLPQRLQEWNLTPSRAAEETRKHLDNIRHKQSLVRFALAELEKRSEELNMVVERAKRSSIDTLGSQDTADMED-EQSMYCITCGHEIHSRTAIKHMEKCFNKYESQASFGSIFKTRMEGNN-MFCDFYNPASKTYCKRLRVLCPEHSKDPKVNDTDVCGSPLVNNVFNPTGEFCRAPKKNCFKHYAWEKIRRAEIDLERVRQWLKMDDLMEQERVMRQQLTSRANLLGLMLHSTYNHEVMDELVRKQQEHLVEFEKQRRRLAHQQQIQTQQKQYQEKQKLMLQQQQQQQQQQQQQQQQQQQQQLQQPQQQQQQQQQQQQEQQQLQLKPHHLQQLQLQLLQQQQKKAQIPQKTQIIYLQKKT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03012-1", "uniprot_id": "SPP1_YEAST", "id": "Q03012-1", "name": "COMPASS component SPP1", "aln": "------------------------------------MSLPQWCPPHSTLKRNPTTGED--VYCICKRPDYGELMVGCDGCDDWFHFTCLHIPEQFKDLVFSFYCPYCQ-----------------------------------------------AGITGKNKDAIINGEGSLPKTLWKR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KCRISDCYKPCLQDSKYCSEEHG--REFVN----DIWSRLKTDEDRAVVKKMVEQTGHIDKFKKFGQLDFIDNNIVVKTDDEKEIFDQIVVRDMTLKTLEDDLQEVQEISLPLFKKKLELLEVYLGWLDNVYTEMRKLDDDAAS-HVECGKEDSKGTKRKKKKNSSRSRARKNICGYCSTYERIP-CSVEEFVRDFGSNEEATKIHEVC--TKWKCNRHLDWVSTN-------QEQYLQQIDSLESMQERLQHLIQARKKQLNIQYYEEILRRGL-------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VQN2-1", "uniprot_id": "Q9VQN2_DROME", "id": "Q9VQN2-1", "name": "PHD-type domain-containing protein", "aln": "-------------------------------------MAPVQKINVFGEADTAVSSKD--VYCICRQSHINGFMICCDNCNEWFHGDCIGLPANIGEQHDTYYCTECFRKNPLLKCTYKKSPSTTGVPKTPKTPKTPKTPKNPKTP--------KTPKNSKTPKTARIINSIGVRQNPRRRSTFVQERPSEVPNP--------------SRQSTKLQKAVNYENATEEPTEDAEKVDQKPKKTAKKKNPKPEDKVT----------------------DDAQKPAVEKLFESKGTQCNMFRDWSKYVPPENSKK----------------------------------------------------------------------------------------------------RGTCFTVFCQQLARSCSRYCCDECGNFTAITNVFALGLLPNMPAMKVAMGHVGLLLGNDLTNNQKSNKNSEASESKTETKPKVKKPKSEGRKSRYRSPSSSLERSPDVSRTAAKRPKLQEELPSSSSRSSRKLVEE-SRSETERHKAKHKTSKKEKTSSQRAYSLSPIPSPKSYRAARNTSETAPNSPVNLKKTFKQKHVISSPTGKKRVCRSQTISADDPLPSQPKS------TEVSPMASAGTSSSNKKPVPETSCQKYRKLSFTDENCEKIKIIRCIVSNMSPTEKALLARKRMMMKLASEQHIRQAPGEI------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: ****: .. . :*: **.*::*:* *: :. : . :** * . .. : * * . *:**.:. * :. : .. :. : . : : : . : . :: : : : : : .. . . . . . . .* . .. . . . . :. : : * : . : ", "identical_positions": 22, "similar_positions": 73, "identity": "2.71%" }, { "cls_id": "homologset.agr.SGD:S000006061", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62862-1", "uniprot_id": "MP2K5_RAT", "id": "Q62862-1", "name": "Dual specificity mitogen-activated protein kinase kinase 5", "aln": "-----------------------------------MLWLALGPFRAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIF-------PRACKPPGERNIHG---LKVNTRAGPSQHTSPVVSDSLPSNSLKKSSAELRKILANGQMN---EQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVI-LLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVE--NRISICTEFMDGGSLDVYRK--------IPEHVLGRIAVAVVKGLTYLWS-LKILHRDVKPSNMLVNTSGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYP-------------------QIQKNQGSLMPLQLLQCIVDEDSPVLPLG----EFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNATVVSMWVCRALEERRSQQGPP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVS7-1", "uniprot_id": "MP2K5_MOUSE", "id": "Q9WVS7-1", "name": "Dual specificity mitogen-activated protein kinase kinase 5", "aln": "-----------------------------------MLWLALGPFCAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIF-------PRACKPPGERNIHG---LKVNTRAGPSQHTSPVVSDSLPSNSLKKSSAELRKILANGQMN---EQDIRYRDTLGHGNGGTVYKAHHVPSGKILAVKVI-LLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVE--NRISICTEFMDGGSLDVYRK--------IPEHVLGRIAVAVVKGLTYLWS-LKILHRDVKPSNMLVNTGGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYP-------------------QIQKNQGSLMPLQLLQCIVDEDSPVLPLG----EFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNSTVVSMWVCRALEERRSQQGPP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13163-1", "uniprot_id": "MP2K5_HUMAN", "id": "Q13163-1", "name": "Dual specificity mitogen-activated protein kinase kinase 5", "aln": "-----------------------------------MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIF-------PRACKPPGERNIHG---LKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMN---EQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVI-LLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVE--NRISICTEFMDGGSLDVYRK--------MPEHVLGRIAVAVVKGLTYLWS-LKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYP-------------------QIQKNQGSLMPLQLLQCIVDEDSPVLPVG----EFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVSMWVCRALEERRSQQGPP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24324-1", "uniprot_id": "DSOR1_DROME", "id": "Q24324-1", "name": "Dual specificity mitogen-activated protein kinase kinase dSOR1", "aln": "----------------------------------------------MSKNKLNLVLPPVNTEATVAAATVAP---------------------------------------------------------------------------TPPFKTPSGTDTHS---LLGKPKTSIDALTETLEGLDMGDTERKRIKMFLSQKEKIGELS---DEDLEKLGELGSGNGGVVMKVRHTHTHLIMARKLI-HLEVKPAIKKQILRELKVLHECNFPHIVGFYGAFYSD--GEISICMEYMDGGSLDLILKRAG----RIPESILGRITLAVLKGLSYLRDNHAIIHRDVKPSNILVNSSGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPNTATLESIFADNAEESGQPTDEPRAMAIFELLDYIVNEPPPKLEHK----IFSTEFKDFVDICLKKQPDERADLKTLLSHPWIRKA-ELEEVDISGWVCKTMDLPPSTPKRNTSPN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32491-1", "uniprot_id": "MKK2_YEAST", "id": "P32491-1", "name": "MAP kinase kinase MKK2/SSP33", "aln": "MASMFRPPESNRSHQKTPKLTLPVNLVQNAKSTNDGQHLNRSPYSSVNESPYSNNSTSATSTTSSMASNSTLLYNRSSTTTIKNRPVPPPLPPLVLTQKKDGIEYRVAGDSQLSERFSNLHVDITYKELLSSAPISTKLSNIDTTFIKKDLDTPEGEDSYPSTLLSAYDFSSSGSNSAPLSANNIISCSNLIQGKDVDQLEEEAWRFGHLKDEITTLGILGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHE-RKVIHRDIKPQNILLNEKGEIKLCDFGVSGEAVNSLAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFE--------------------SDKITQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQMLKHPWIVGQ-MKKKVNMERFVKKCWEKEKDGI-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:. .: : : ..* : : * :. . : . . .: . . : : . .::: . ** * ** * * ::* * * :: :***: **:. . . :*: :** * : . * *. *:*.* **: * :.* ::*:*: :*::**:** . ::***:**.*:*:* *::*:****** : ::*:* ::.** **:***:.* *.: .*:****::::*:* * :* . : ::** *: . :* * *: *::*:. **. . :: **:* : . :. :* : : . ", "identical_positions": 87, "similar_positions": 114, "identity": "16.26%" }, { "cls_id": "homologset.agr.SGD:S000006062", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88866-1", "uniprot_id": "HUNK_MOUSE", "id": "O88866-1", "name": "Hormonally up-regulated neu tumor-associated kinase", "aln": "----MPAAAGDG---------------------------LLGEPAAPGGDGGAEDTTRPAAACEGSFLPAWVS-------------------------------------------------GVSRERLRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLDEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLA-RKKYG-PKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKAMNPLPTQLS----TGAVNFLRSLLEPDPVKRPNIQQALANRWLNEN-YTGKVPCNVTYPNRISLEDLSPS--VVLHMTEKLGYKNSDVINTVLSNRACHILAIYFLLNKKLERYLS-----GKSDIQDSICYKTQLYQIEKCRATKEPYEASLDTWTRDFEFHAVQDKKPKEQEKRGDFLHR-----------------------PFSKKLDKN-----------------------------LPSHKQPSPS-------------------------------------------------------------------------LITQLQSTKALLKD-----------------------------------------------------RKASKSGFPDKDSFVCRNLFRKTSDSNCVASSSMEFIPVPPPRTPRIVKKLEPHQPG-----------------------------------------PGSASILPK-----------------EEPLLLDMVRSFESVDREDHIELLSPSHHYRILS-----------------------------------------------------------SPVSLARRNSSERTLS---------------------------------------------------------------QGLLSGS------------------------TSPLQTPLHSTLVSFAHEEKNSPPKEE--------------------------------------------------------------------------GVCSPPPVPS------------NGLLQPLGSPNCVKSRGRFPMMGIGQMLRKRHQSLQPSSE--------------RSLDASMSPLQPTAPS-------------------------------------------SLSFDMADGVKGQC----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZV60-1", "uniprot_id": "A0A8I5ZV60_RAT", "id": "A0A8I5ZV60-1", "name": "Hormonally up-regulated neu tumor-associated kinase", "aln": "----MPAAAGDG---------------------------LLGEPAAPGGDGGAEDTARPAAACEGSFLPAWVS-------------------------------------------------GVSRERLRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLDEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLA-RKKYG-PKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLS----TGAINFLRSLLEPDPVKRPNIQQALANRWLNEN-YTGKVPCNVTYPNRISLEDLSPS--VVLHMTEKLGYKNSDVINTVLSNRACHILAIYFLLNKKLERYLS-----GKSDIQDSICYKTQLYQIEKCRATKEPYEASLDTWTKDFELHAVQDKKPKEQDKRADFLHR-----------------------PFSKKLDKS-----------------------------LPSHKQPSPS-------------------------------------------------------------------------LITQIQNTKALLKD-----------------------------------------------------RKASKSGFGDKDSFGCRNLFRKTSDSNCVASSSMEFIPVPPPRTPRIVKKQEPHQPG-----------------------------------------PGSASMLPK-----------------EEPLLLDMVRSFESVDREDHIELLSSSHHYRILS-----------------------------------------------------------SPVSLARRNSGERTLS---------------------------------------------------------------PGLLSGS------------------------TSPLQTPLHSTLVSFTHEEKNSPPKEE--------------------------------------------------------------------------GVCSPPPVPS------------NGLMQPLGSPNCVKSRGRFPMMGIGQMLRKRHQSLQPSSE--------------RSLEVSMSPLQPTAPS-------------------------------------------SLSFDMADGVKGQC----------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57058-1", "uniprot_id": "HUNK_HUMAN", "id": "P57058-1", "name": "Hormonally up-regulated neu tumor-associated kinase", "aln": "----MPAAAGDG---------------------------LLGEPAAPGGGGGAEDAARPAAACEGSFLPAWVS-------------------------------------------------GVPRERLRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLA-RKKYG-PKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLS----TGAISFLRSLLEPDPVKRPNIQQALANRWLNEN-YTGKVPCNVTYPNRISLEDLSPS--VVLHMTEKLGYKNSDVINTVLSNRACHILAIYFLLNKKLERYLS-----GKSDIQDSLCYKTRLYQIEKYRAPKESYEASLDTWTRDLEFHAVQDKKPKEQEKRGDFLHR-----------------------PFSKKLDKN-----------------------------LPSHKQPSGS-------------------------------------------------------------------------LMTQIQNTKALLKD-----------------------------------------------------RKASKSSFPDKDSFGCRNIFRKTSDSNCVASSSMEFIPVPPPRTPRIVKKPEPHQPG-----------------------------------------PGSTGIPHK-----------------EDPLMLDMVRSFESVDRDDHVEVLSPSHHYRILN-----------------------------------------------------------SPVSLARRNSSERTLS---------------------------------------------------------------PGLPSGS------------------------MSPLHTPLHPTLVSFAHEDKNSPPKEE--------------------------------------------------------------------------GLCCPPPVPS------------NGPMQPLGSPNCVKSRGRFPMMGIGQMLRKRHQSLQPSAD--------------RPLEASLPPLQPLAPV-------------------------------------------NLAFDMADGVKTQC----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W532-1", "uniprot_id": "Q9W532_DROME", "id": "Q9W532-1", "name": "non-specific serine/threonine protein kinase", "aln": "MSTCEAAAAGENGSQAKSEESQPPEDQKKKQPQHERNEKQLDKPPENLPQNGKTEAKGAEGACSHPPLDALRSSVLLDAGAASPSIDAIVACKDALLAQKLFASGGGSTPGPSPTSSAVGAGGISGKDLLKLKEPMRVGFYDIER-TIGKGNFAVVKLARHRITKNEVAIKIIDK--SQLDQTNLQKVYREVEIMKRLKHPHIIKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIISAVEYCHKKGIVHRDLKAENLLLDLNMNIKIADFGFS---NHFKPGELLATWCGSPPYAAPEVFE-GKQYTGPEIDIWSLGVVLYVLVCGALPFDGS--TLQSLRDRVLSGRFR-IPFFMS----SECEHLIRRMLVLEPTRRYTIDQIKRHRWMCPE-LLEHVLIAKYNLGAERQTSVEPSEDILRIMAEYVGIGSDKTRASLKKNTYDHVAAIYLLLQDRVSHKKEQSNGLGASALASSTSASRMIYSSRNDHQPTQQQSQQQSKTISTSSILAKDQCHKRLSRHQTVLMSERNAHAGATPTVPDPGPGYYAKYGPLQLPLPLTGHSHLTGYLNGGGVEVDASGIPLPMRYTPLPTAASPAPSNCSSTSSRVGRHSLSSSSPRSHRPVAISLSIDNNPSLANLRCREMMEAGGGPVGAVGVPLASKQLHQTISEFIIKQSTEDCRALLQQSTAVAEGKDDPPKAESSVGGVPPPASTTPTSSTAGPESGSAPCPGEINGKTIKTMSSSSSFDSKANLGQSFRYKMSAEASKLFQTLQESPLPVEQRTKRRVHVGSTNGSGGDSGQETNDAKSNGDSRSEKKVLAQGSSSTDEGCETDQGNDPGSASQESKGSNGGGSGNANGGPTSHSSSDLTRLVGTTTSGQSHKMRSYASSSSSSGVLAGSAGSYSKSLSQNLSRGSSKSNCSGPYDSLDFALPSGKGSLPSCMGSSSMLATPTPASASPAGISSEHSSERSLYGSHNSCIHMPGALPLGLGLPQSSASTPTPNPTPPPNGGGVTFLDKRSPIHFREGRRASDGLVAQGLLSSGSLLGTSRVYGSYRYEQAKRHGWLEIQQLQQLQQEAAVGHSHPHAHQHPHQHPHPHPQAYGLEELCQFPNGQFYALPGKHHPLLTLPHHHAHPAQHHHGHHSLFHSGHQATPLLLEAAAGGDMYGHGCYAPPPPPPGLYTHHQLGVGMAVPMSPMQKPPLQQQLLQHRLLQQKRQLFQKQYALEAQLAGRHHHHQQHSHHHHHHFGHSLGPPPPPAPAPEHHLADELYELALLDRPRSGTPRLQHSMTMPGAHAFSQMNLKTSYISQSDQVPGAAPNGAGSGGSAAGVSCSAPPSTAPGTPTVKCKPTTPHGHSLDSDYHTSTPVLSLFTPNWQSLVKPLSESPILEISEHLESV--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03002-1", "uniprot_id": "FRK1_YEAST", "id": "Q03002-1", "name": "Fatty acyl-CoA synthetase and RNA processing-associated kinase 1", "aln": "---------------------------------------MSYTNKRHTYYGGFTNDLSDTFQYPQRTDEQRRK----------------------------------------------------HVTFGPYILGSTLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVN--EFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLYNYINSTPLKFPDYILPIPRDLLRRMLVSDPKKRINLKQIKKHEWLKPHSSFLSITPDEWDKLNNTQSVFRLAKPRRRYGSRPQSSCSTSSLGSRSDKRDSLVIDSTLITFPAPPQESQNHIITRPASIASDQRLSPIRRSNRHNRSNSAASVALQAVVNADREYVLSHEQSLSPVQNIRQTTGN--------------------MTASLSPPPAISPGD--------------------------IIIETTPIKRN------------------------------------------------------------------------TISGSSIVPSLEEESS--------------------------------------------------TTMQTSKIQPNNMASSQNHQYNKNKTQNSLQSAKNFYRTSSSSHTKPRPTSYHPGSYTTP---------------------------------------PYNSNTLSIYEIN--------EKAKSSASSQTLNQRDTSPFDSTPYLALDTCITSSSSIE----------------------------------------------------------SSPKLITHGQFSVAKPS---------------------------------------------------------------VDLQSVSG------------------------DLIKYKRDADVVTRIYDEKYKQKRKSLRYSG-------------------------------------------------------IFSDISCDTVTEESDELRPPESPLQQHEGQESIDKAKTEDTSEKGSKSSNIAKATAQKHVNNHLERSLNEAESTKKRFSFLSLYSYDTSKSSLYSSMDSKRKPSPPS------------------------------------------QRRPKKDDSYQTNSKNHYITASNMQTSHQVSKDLPAPTMVQNKCTLETKKAVRSNRSSIMVSEVNKASVDNKAAQSPEHSTAKRVLGFFKRRSMKI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* : . : :* : .:* . ::****:*.: . * :: ** : : : **:* :* ::::... :* * . *:: . * : *:.* * : *:**.*.: * *:****** ****** : *: : ***: .: : * **** *****:. : * : *:** ** :*.:: * **: . . .. : :. * :. . ::* :* :* :* .:.* :.*: . : . : :. . . . : .: : :: : . : : .. . . .: : . . .: : . .:. . : * . :* :: :.. .: :. . . : .: :* . * .:. . . . : : : ** :: : . . .* * . . :: . * : . . :: . ** * . . : . * : :. : *: . :* . * . ", "identical_positions": 87, "similar_positions": 175, "identity": "6.15%" }, { "cls_id": "homologset.agr.SGD:S000006064", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55142-1", "uniprot_id": "RL35A_MOUSE", "id": "O55142-1", "name": "Large ribosomal subunit protein eL33", "aln": "------------------------------------------------------------------------------------MSGRLWCKAIFAGYKRGLRNQREHTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRV--IWGKVTRAHGNSGMVRAKFRSNLPAKAIGHRIRVMLYPSRI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GLI9-1", "uniprot_id": "A0A8I6GLI9_RAT", "id": "A0A8I6GLI9-1", "name": "Large ribosomal subunit protein eL33", "aln": "MRDERKEKNRKTKRRDKKSKVFERGLAESSLSLTFAFWRSTSGLSVERGGACIPQGRAAGLAFLFPPSWRLWRPAGNRTSKKTSMSGRLWCKAIFAGYKRGLRNQREHTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRV--IWGKVTRAHGNSGMVRAKFRSNLPAKAIGHRIRVMLYPSRI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18077-1", "uniprot_id": "RL35A_HUMAN", "id": "P18077-1", "name": "Large ribosomal subunit protein eL33", "aln": "------------------------------------------------------------------------------------MSGRLWSKAIFAGYKRGLRNQREHTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRV--IWGKVTRAHGNSGMVRAKFRSNLPAKAIGHRIRVMLYPSRI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8L2QJQ6-1", "uniprot_id": "A0A8L2QJQ6_RAT", "id": "A0A8L2QJQ6-1", "name": "Large ribosomal subunit protein eL33", "aln": "------------------------------------------------------------------------------------MSGRLWCKAIFAGYKPGLLNQREYTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRV--IWGKVTRAHGNSGVVRAKFQSNLPAKAIGHRIRVMLYPSQI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VNB9-1", "uniprot_id": "Q9VNB9_DROME", "id": "Q9VNB9-1", "name": "Large ribosomal subunit protein eL33", "aln": "---------------------------------------MADTQAKSTTAPKAAKAQKAPKAVKAPKAEKPAASEAKVSAKKYKRHGRLFAKAVFTGYKRGLRNQHENQAILKIEGARRKEHGSFYVGKRCVYVYKAETKKCVPQHPERKTRVRAVWGKVTRIHGNTGAVRARFNRNLPGHAMGHRIRIMLYPSRI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05744-1", "uniprot_id": "RL33A_YEAST", "id": "P05744-1", "name": "Large ribosomal subunit protein eL33A", "aln": "----------------------------------------------------------------------------------MAESHRLYVKGKHLSYQRSKRVNNPNVSLIKIEGVATPQDAQFYLGKRIAYVYRAS--KEVRG---SKIRV--MWGKVTRTHGNSGVVRATFRNNLPAKTFGASVRIFLYPSNI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: *. . .*: . :. :::****. :. .**:*** .***:*. . . * ** :****** ***:* *** *. ***.:::* :*::****.*", "identical_positions": 44, "similar_positions": 32, "identity": "22.45%" }, { "cls_id": "homologset.agr.SGD:S000006066", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "S4R1M9-1", "uniprot_id": "OSB10_MOUSE", "id": "S4R1M9-1", "name": "Oxysterol-binding protein-related protein 10", "aln": "---------MERAAQSTDGGGGGGSNSSSRSSSRATSAGSSPSCSLAGRGVASRSGAAGLGGGGSRSSPGSVAASPSGGGGRRR-------EPALEGVLSKYTNLLQGWQSRYFVLDFEAGLLQYFVNEQSKHQKPRGVLSLSGAIVSLSDEAPHMLVVYSANGEMYKLRAADSKEKQLWVTQLRACAKYHMEMSSKTTPGSRSRSLTLLPHGTPSSASPCSQRHLSTGAPGVVSVTRHKSPAAARRAKSQYSGQLHEVREMMNQVEGQQKNLVHAIESLPGSGPLTALDQDL-LLLKATSAATLSCLGECLSLLQQSVRQAAPPSHKPGASETILGWHGPTSHSTDQLKNGTLGSLPSASANITWAILPNSAEEEHNSQPEPEPDSGPELVLSEE--EQSDNEDKGEVEPGAMEDQRSVILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVISFVEYYLTAFHEG-----RKGTLAKKPYNPIIGETFHCSWEVPKDRVKS-KWTSPHPPISAHEHPMADD-----PSKSYKLRFVAEQVSHHPPISCFYCECKEKRLCVNTHVWTKSKFMG-MSVGVSMIGEGVLRLLDHGEEYVFTLPSAYAR-SILTVPWVELGGKVNISCAKTGYSATVTFHTKPFYGGKVHRVTAEVKHNP-----TNTIVCKAHGEWNGTLEFTYS--------------------------------------------------------------------------------------NGETKVIDTTTLPVYPKKLRPLEKQ--GPMESRNLWQEVTHYLRLGDIDAATEQKRRLEERQRVEERKR-ETLRTPWRPKYFIPEGD------GWVYFN----------------------------------------PLWKTH---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LWM8-1", "uniprot_id": "F1LWM8_RAT", "id": "F1LWM8-1", "name": "Oxysterol-binding protein", "aln": "---------MERAAQSADGGGGGGSNSSSRSSSRATSAGSSPSCSLAGRGVASRSGAAGLGGGGSRSSPGSVAASPSGGGGRRR-------EPALEGVLSKYTNLLQGWQNRYFVLDFEAGLLQYFVNEQSKHQKPRGVLSLSGAIVSLSDEAPHMLVVYSANGEMYKLRAADSREKQLWVTQLRACAKYHMETSSKTTPGSRSRSLTLLPHGTPSSASPCSQRHLSAGAPGVVSVTRHKSPAAARRAKSQYSGQLHEVREMMNQVEGQQKNLVHAIESLPGSGPLTALDQDL-LLLKATSAATLSCLGECLTLLQQSVRQAGPPSHKPGASESILGWHGPTSQSTDQLKNGTLGSLPSASANITWAILPNSAEEEHSSQPEPEPDSGPELVLSEE--EQSDHEDKGEVEPGTVEDQHSVILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVISFVEYYLTAFHEG-----RKGTLAKKPYNPIIGETFHCSWEVPKDRVKS-KWTSPHPPISCHEHPMADD-----PSKSYKLRFVAEQVSHHPPISCFYCECKEKRLCVNTHVWTKSKFMG-MSVGVSMIGEGVLRLLDHGEEYVFTLPSAYAR-SILTVPWVELGGKVNISCAKTGYSATVTFHTKPFYGGKVHRVTAEVKHNP-----TNTIVCKAHGEWNGTLEFTYS--------------------------------------------------------------------------------------NGETKVIDTTTLPVYPKKLRPLEKQ--GPMESRNLWQEVTHYLRLGDIDAATEQKRRLEEKQRTEERKR-ETLRTPWRPKYFIPEGD------GWVYFN----------------------------------------PLWKTH---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BXB5-1", "uniprot_id": "OSB10_HUMAN", "id": "Q9BXB5-1", "name": "Oxysterol-binding protein-related protein 10", "aln": "---------MERAVQGTDGGG--GSNSSSRSSSRATSAGSSPSCSLAGRGVSSRSAAAGLGGGGSRSSPGSVAASPSGGGGRRR-------EPALEGVLSKYTNLLQGWQNRYFVLDFEAGILQYFVNEQSKHQKPRGVLSLSGAIVSLSDEAPHMLVVYSANGEMFKLRAADAKEKQFWVTQLRACAKYHMEMNSKSAPSSRSRSLTLLPHGTPNSASPCSQRHLSVGAPGVVTITHHKSPAAARRAKSQYSGQLHEVREMMNQVEGQQKNLVHAIESLPGSGPLTALDQDL-LLLKATSAATLSCLGECLNLLQQSVHQAGQPSQKPGASENILGWHGSKSHSTEQLKNGTLGSLPSASANITWAILPNSAEDEQTSQPEPEPNSGSELVLSED--EKSDNEDKEETELGVMEDQRSIILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVICFVEYYLTAFHEG-----RKGALAKKPYNPIIGETFHCSWEVPKDRVKP-KRTASRSPASCHEHPMADD-----PSKSYKLRFVAEQVSHHPPISCFYCECEEKRLCVNTHVWTKSKFMG-MSVGVSMIGEGVLRLLEHGEEYVFTLPSAYAR-SILTIPWVELGGKVSINCAKTGYSATVIFHTKPFYGGKVHRVTAEVKHNP-----TNTIVCKAHGEWNGTLEFTYN--------------------------------------------------------------------------------------NGETKVIDTTTLPVYPKKIRPLEKQ--GPMESRNLWREVTRYLRLGDIDAATEQKRHLEEKQRVEERKR-ENLRTPWKPKYFIQEGD------GWVYFN----------------------------------------PLWKAH---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CI95-1", "uniprot_id": "OSB11_MOUSE", "id": "Q8CI95-1", "name": "Oxysterol-binding protein-related protein 11", "aln": "----------------MQGGE---PASVMKVSESEGKLEGLATAVTPNKNSGNSSCGGAIS---SSSSNSSRGGSAKGWQYSDH-------MESVNGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSGN----SPISQRRPSQNAMSFFNVGHSKLQSVNKRAH-LHPDHLVEVREMMSHAEGQQRDLIRRIECLPASGLLSSLDQDL-LMLKATSMATMNCLNDCFHILQL---QHASHQKGALPSGTTIEWLEPKIPLSNHYKNGAEQPFATEPN------KPMGAPEAQCVAESGVLAREPEDISADD--EVEDTCDNKEDDLGAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIGITNGATPEDRMIRFVEYYLTSFHEG-----RKGAIAKKPYNPIIGETFHCSWRMPKSEVASGVSSSSSTPAITDHAPLPEEAPTQSVSDCYTVRFVAEQVSHHPPVSGFYAECAERKMCVNAHVWTKSKFLG-MSIGVTMVGEGVLCLLEHGEEYTFSLPCAYAR-SILTVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKYNL-----TNTVVCRVQGEWNSVLEFTYS--------------------------------------------------------------------------------------NGETKFVDLAKLAVTKKRVRPLEKQ--DPFESRRLWKNVTDSLRESEIDKATEHKRSLEERQRTEERLR-TETGTPWKTKYFIKEGD------GWVYHK----------------------------------------PLWKGIPS-QPAE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXB4-1", "uniprot_id": "OSB11_HUMAN", "id": "Q9BXB4-1", "name": "Oxysterol-binding protein-related protein 11", "aln": "----------------MQGGE---PVSTMKVSESEGKLEGQATAVTPNKN---SSCGGGIS---SSSS--SRGGSAKGWQYSDH-------MENVYGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSSN----SPISQRRPSQNAISFFNVGHSKLQSLSKRTN-LPPDHLVEVREMMSHAEGQQRDLIRRIECLPTSGHLSSLDQDL-LMLKATSMATMNCLNDCFHILQL---QHASHQKGSLPSGTTIEWLEPKISLSNHYKNGADQPFATDQS------KPVAVPEEQPVAESGLLAREPEEINADD--EIEDTCDHKEDDLGAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEG-----RKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLG-MSIGVTMVGEGILSLLEHGEEYTFSLPCAYAR-SILTVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKHNI-----TNTVVCRVQGEWNSVLEFTYS--------------------------------------------------------------------------------------NGETKYVDLTKLAVTKKRVRPLEKQ--DPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHR-TETGTPWKTKYFIKEGD------GWVYHK----------------------------------------PLWKIIPTTQPAE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z814-1", "uniprot_id": "A1Z814_DROME", "id": "A1Z814-1", "name": "Oxysterol-binding protein", "aln": "MASTTGSAPSLGPPQSGSGGSGTLEGTLSKWTNVMKGWQYRFFVLDENAGLLSYYTSKDKMIKGVRRGCVRLKDALIGIDDQEDNTFTITVDHKTFHFQARHNEEREQWVRRLEDTIRRHANRSRLWDSQSAFYIAGGYTKEGGGSGTGGRRPNHLELVARRVSEADAYLQLMIEQTNLLDKRIAELTDPAEQSKCKALQDNANAMLDHIKHSIVSLQIAKNMAHPINGIYNGPPATASTSSSTSGVAMGSCNN--VQAGGLKVPLEGQVIGKGELVDDEEDSATENATTAPLGLIVPATSYSSSEGEEDFYDAYDDPFTSIGSSPIGCATRGFAETTSPTHEKAPDGFANAEPVAVGDSVAPQTLPEIDESVADADTSIKTARTAVSSRSASYDNGIDYDALYEEEEETDLSMEAHGSMITHLLSQVKIGMDLTKVVLPTFILERRSLLEMYADYFAHPDLFIKISDLDDPRDRIVQVCRWYMSAYHAG-----RKSAVAKKPYNPILGEVFQCHWDIPGISQDAQEVRDGPVPWCRRDQ----------------LTFLAEQVSHHPPISAFYAEHYNKKITFAAHVWTKSKFLG-LSIGVHNIGEGVVTLVDRSEEYIVTFPNGYGR-SILTVPWIELGGSVEIKCPQSGYYANVEFLTKPFYGGKRNRVSAEVYAPS-----EKKPFVSITGEWSGLMEAKWHD------------------------------------------------------------------------------------KNKTEVFVDVNRIPIFKKQVRPIVEQ--DEYESRRVWKEVTAGLKFNDIERATTAKFVVEQQQRDQAKVR-KEYDLAWEHKHFKPVGD------NWIYAK----------------------------------------PLSQRMYLQEKEAKR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8BX94-1", "uniprot_id": "OSBL2_MOUSE", "id": "Q8BX94-1", "name": "Oxysterol-binding protein-related protein 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNGEEEFFDAVTGFDSDNSSIGEFSEAN-KISGMIDLDTSKSTRSG------------------KNGEKPQQENGIQKHRTALPAPMFTRSD-----------------------FSVWSILKKCIGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHKASSQSQPLERMQSVAAFAVSAVAS-------QWERTGKPFNPLLGETYELIREDLG------------------------------------FRFISEQVSHHPPISAFYSEGLNQDFRFHGSIYPKLKFWG-KSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVILGQLWIEQYGIVEIVNHRTGDKCILHFKPCGLFGKELHRVEGYIQDKN-----RKK-LFIMYGKWTECLWGIDPASYESFKKQEKRGDQARKAKMDDGPEK----------------------ANSDVPGDVADDVPVAQETVQV-IPGSKLLWRINSRPPNSAQMYNFTSFTVSLNELESGMEK--TLPPTDCRLRPDIRGMENGNMDLASQEKERLEEKQREARKER-AKEDAEWRTRWFSPGNNPYTGAPDWLYAG----------------------------------------HYFERNFSDCPDIY-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AI28-1", "uniprot_id": "A0A8I6AI28_RAT", "id": "A0A8I6AI28-1", "name": "Oxysterol-binding protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNGEEEFFDAVTGFDSDNS-TGEFSEAN-KITGMIDLDTSKSTRSG------------------KHGERSPQENGIQKHRTALPAPMFTRSD-----------------------FSVWSILKKCIGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASNQSQPLERMQSVAAFAVSAVAS-------QWERTGKPFNPLLGETYELIREDLG------------------------------------FRFISEQVSHHPPISAFYSEGLNQDFMFHGSIYPKLKFWG-KSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVILGQLWIEQYGIVEILNHRTGDKCILHFKPCGLFGKELHRVEGYIQDKN-----RKK-LFIMYGKWTECLWGIDPVSYESFKKQEKRGDHARKAKSDDAPEK----------------------VNSDVPGNMADDVPVAQETVQV-IPGSKLLWRINSRPPNSAQMYNFTSFTVSLNELESGMEK--TLPPTDCRLRPDIRGMENGNMDLASQEKERLEEKQREARKER-AKEEAEWRTR---PVHTSTVAVSIRTCTR----------------------------------------RLIVSRWNHDK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H1P3-1", "uniprot_id": "OSBL2_HUMAN", "id": "Q9H1P3-1", "name": "Oxysterol-binding protein-related protein 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNGEEEFFDAVTGFDSDNS-SGEFSEANQKVTGMIDLDTSKNNRIG------------------KTGERPSQENGIQKHRTSLPAPMFSRSD-----------------------FSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSAVAS-------QWERTGKPFNPLLGETYELIREDLG------------------------------------FRFISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWG-KSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKN-----KKK-LFMIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGK----------------------ADSDV----ADDVPVAQETVQV-IPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEK--TLPPTDCRLRPDIRGMENGNMDLASQEKERLEEKQREARRER-AKEEAEWQTRWFYPGNNPYTGTPDWLYAG----------------------------------------DYFERNFSDCPDIY-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4LGH8-1", "uniprot_id": "A0A0B4LGH8_DROME", "id": "A0A0B4LGH8-1", "name": "Oxysterol-binding protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEGDYAEHVERTELPATMISRKE-----------------------VSIWAILKNCIGKDLSKITMPVMLNEPLSFLQRLCEYMEYAQLLTEAAQQEHPADRMKYVAAFAVSALAS-------NWERLGKPFNPLLGETYELQKGD--------------------------------------YRIVCEQVSHHPPVSAFHAE--SKDFKFHGTISPKIKFWG-KSVEVNPKGTVTVEFPKWNESYSWTNVNCCVHNIIVGRLWIEQYGKMEITNHATGHVASLTFKSAGSGAKNLHRVEGFVKDAS-----ETN-LYFLYGKWTEFIKCCSAESYVQFLKQGTRKNDDYDGSPNGTPKKMFSKLNSFKLNSFRSLSIQDVSSDSYPPMEQEGDIPKSDSAYSLDIPDSTTLWSCKPRPSNCSEYYQFTHFALQLNAMDSNMKPPLTLCPTDSRLRPDILHLEEGNLDGASKEKTRLEEKQRHTRKQRKSTNSDDWSPRWFKYATNPHTKIDDWLYSG----------------------------------------GYWDRKYDNTDTIF-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35844-1", "uniprot_id": "KES1_YEAST", "id": "P35844-1", "name": "Oxysterol-binding protein homolog 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQYASSSSWTSFLKSIASFNGDLSSLSAP-----------------------PFILSPISLTEFSQYWAEHPELFLEP----SFINDDNYKEHCLIDPEVESPELARMLAVTKWFISTLKSQYCSRNESLGSEKKPLNPFLGELFVGKWENKEHPEFG------------------------------ETVLLSEQVSHHPPVTAFSIFNDKNKVKLQGYNQIKASFTKSLMLTVKQFGHTMLDIKD--ESYLVTPPPLHIEGILVASPFVELEGKSYIQSS-TGLLCVIEFSGRGYFSGKKNSFKARIYKDSKDSKDKEKALYTISGQWSGSSKIIKAN-----------------------------------------------------------------------------------KKEESRLFYDAARIPAEHLNVKPLEEQ--HPLESRKAWYDVAGAIKLGDFNLIAKTKTELEETQRELRKEE-EAKGISWQRRWFKDFDYSVTPEEGALVPEKDDTFLKLASALNLSTKNAPSGTLVGDKEDRKEDLSSIHWRFQRELWDEEKEIVL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * : * . : : *: . : ::: . ** **::** : ::.********:: * .. . . * .* : . * : : . * * : . :: ::* * : :* . : * . : : . . : . . *:*. : :. : . : : :. .::: : * :*: ** : . * : ", "identical_positions": 34, "similar_positions": 70, "identity": "3.59%" }, { "cls_id": "homologset.agr.SGD:S000006067", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BK35-1", "uniprot_id": "NOP53_MOUSE", "id": "Q8BK35-1", "name": "Ribosome biogenesis protein NOP53", "aln": "MAAGGNRDGEKRGSRSQADSGFLGLR---PTSVDPALRRRRRGPRNKKRGWRRLAEEPLGLEVDQFLEDVRLQERTTGG-LLAEAPNEKLFFVDTGFKRKEPRKKRTLVQKKSQRLQKPLRVDLALENHSKIPAPKDILAHQ-VPNAKKLRRKEELWEKLAKQGELPRDVRKAQARLLSPP---TPKAKPGPQDII--ERPFYDLWNPDNPLDTPLIGQDAFFLEQTK-KKGVRRPQRLHIKPSQVPAV-EVIPAGASYNPTFEDHQALLREAHEVELQREKEAEKLERQLALPTSEQAATQES--VFREMCEGLLEESDGEDEHEAGRAGQPEAGDGTTEISPTGAAGPEKRMEKKTEQQRRREKAARKLRVQQAALRAARLQHQELFRLRGIKAQVARRLAELARRREQRRIRRLAEADKPRRLG-RLKYQAPDIDVQLSSELSGSLRTLKPEGHILRDRFKSFQKRNMIEPRERAKFKRKYKVKLVEKRAYREIQL------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6QLN3-1", "uniprot_id": "Q6QLN3_RAT", "id": "Q6QLN3-1", "name": "", "aln": "MAAGSNRGGDKRGSKSQADSNFLGLR---PTSVDPALRRRRRGPRNKKRGWRRLAEEPLGLEVDQFLEDVRLQERTTGG-LLAEAPNEQLFFVDTGLKKKEPRKKRTWVQKKSKHLQKPLRVDLALENHSKIPAPKDILAHQ-VPNAKKLRRKEELWEKLAKQGELPRDVRKAQARLLNPP---APKAKPGPQDII--ERPFYDLWNPNNPLDKPLIGQDAFFLEQTK-KKGVRRPPRLHIKPSQVPAV-EVIPAGASYNPTFEDHQALLLEAHEVELQREKEAEKLERQLALPTAEQAATQES--VFREMCEGLLEES--EDEDGPGCAEQPEADDGATETSPTGAAGPEKRMEKKTEQQRRREKAARKLRVQQAALRAARLQHQELFRLRGIKAQVARRLAELARRKEQRRIRRLAEADKPRRLG-RLKYQAPDIDVQLSSELSDSLRKLKPEGNILRDRFKSFQKRNMIEPRERAKFKRKYKVKLVEKRAFREIHSTLCPQVVAVQMLEPLPLNKVL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NZM5-1", "uniprot_id": "NOP53_HUMAN", "id": "Q9NZM5-1", "name": "Ribosome biogenesis protein NOP53", "aln": "MAAGGSGVGGKRSSKSDADSGFLGLR---PTSVDPALRRRRRGPRNKKRGWRRLAQEPLGLEVDQFLEDVRLQERTSGG-LLSEAPNEKLFFVDTGSKEKGLTKKRTKVQKKSLLLKKPLRVDLILENTSKVPAPKDVLAHQ-VPNAKKLRRKEQLWEKLAKQGELPREVRRAQARLLNPS---ATRAKPGPQDTV--ERPFYDLWASDNPLDRPLVGQDEFFLEQTK-KKGVKRPARLHTKPSQAPAV-EVAPAGASYNPSFEDHQTLLSAAHEVELQRQKEAEKLERQLALPATEQAATQES--TFQELCEGLLEES--DGEGEPGQGEGPEAGD--AEVCPTPAR--LATTEKKTEQQRRREKAVHRLRVQQAALRAARLRHQELFRLRGIKAQVALRLAELARRQRRRQARREAEADKPRRLG-RLKYQAPDIDVQLSSELTDSLRTLKPEGNILRDRFKSFQRRNMIEPRERAKFKRKYKVKLVEKRAFREIQL------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NCB9-1", "uniprot_id": "A0A8M1NCB9_DANRE", "id": "A0A8M1NCB9-1", "name": "Ribosome biogenesis protein NOP53", "aln": "MAAAR-----KHKRMAASQPGFLPLKSDLDGSISNAKRRKRVN-KNKKKNWNKYSDIR---DVEDFLDDVRLQEKATGG-LISEKPDDSLFFVDTGEKEKD---KQPQTTAKKGKRSKPLRIDLILQPDSHIPPPKNVLAYQ-QPNAKKQRRMAEKAAKLAAMGVLPRREKLLQLRRAAAASGVSVKEKPVANNNP--ERPFYDLWSEGTPET-----ADPFYLEQTK-KKLIKRPDRLNEKPSVLPAI-EVIAAGGSYNPDFFSHQELLREAHEVEVKKLKVEEKLARQLAVN--QDIATEES--TFKEQVEGLIEED----EDQPEDADG-DADD--TVIGPTAIQ------EKKTERQRKKEKAEKVKELQRKAEREVIDKKQQLFQLRSIRANLKNQEQRTKMRQAQRKAKQEAEKSMPRRLG-RLKYQEPDLDIQLSDELASSLRSLKPEGSILKDRFKSLQKRNLIEPRERAKFKRRYKLKYSEKRAFREIQ-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3C2-1", "uniprot_id": "NOP53_DROME", "id": "Q9W3C2-1", "name": "Ribosome biogenesis factor Nop53", "aln": "-----------------------------MTAVEPATKKKRISKKNKS-AWRKTDIQD----VEQFLEDQRQEERVG---TFADKQDEDLFVVDSSLPKTKATVLSVKQ-KRKLNAKKPMRSYQALENTSKVQDPIAKRNHV-RQKKNGRNIELEVCNPTKPRHRQANSDRAQYYVKLEQRLADKKNKKLDVEKDIWQEVDFRDEIPGLKDEKGWISRELALHTAGNIGKKVVKTHASLHHKTTKAKKF-ELPHPGMSYNPAPEDHQALIDQVVEREEGIIKKEQHLKRVTTSMFSKVTPEERDRRRLNEMSQGMDEEEGSELDEDVQTNGKKKEDDDEKPYHTINAP---VENKKKSKQARRNELKQKELARQTELKRKLKQQTADLIRIKSIRHELDDEEEDLNDLKKRRKQRAEKAKFEPKRLG-RHKFEEPDLDVNLPEDIAGNLRNVKTESSLLKDRFHTLQRNNML-PTTKLVSRKKSKVKRFERNSHKEPGVSYNDLKERRRAAAAAAKATANIKI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12080-1", "uniprot_id": "NOP53_YEAST", "id": "Q12080-1", "name": "Ribosome biogenesis protein NOP53", "aln": "---------------------------MAPTNLTKKPSQYKQSSRKGKKAWRKNIDLS---DVEQYMEKKIDHEITHGTSDITSLQNDALFHVDVE--GDEILKNKLIKRKQIKKVLKSKEILDAVKTNSKIAALNHHKNSSGNPNKIQGVSKHELKKLMALAGRVHGESKIKNRVAKDGLVKTTAGDLWGEESNSKKQKVKLPSGIKLDVEKKDQIPEELLKKSTTSWSTASVRPSTLDIEPIAVKEFTEIPHAGKSYNPNNKAWSELINKEYKEEKAREDERIALEKYKERIRHLMETLDDN---EEEESSSNEEEEEEEEENENENESTQCSGSDKEIKLSINKP---VKNKKKTKYQRNKAKRHEEKVKLQQELKELRQRVKDLEEVINS-----EETEILSAIESDSNKVKKSKKNKKHKLGTKYSVIDERLEIKFSDELSDSLRKLKPEGNLLYDTVRKLQSSGKVETRVPVRKGRKYKQKITEKWTHKDFK-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . :: . *.: *:::::. .* . ::. :: ** ** : *. . :: *:: : : : :. : : . .. *. :. . *: .* **** . *: : * . * : . : . .* .. **. : .. . :**:: *.. . : : :* .: . . . . ::** : . :::::..:::..**.:*.*. :* * .:.:* . : . :: * * *: :.:: ", "identical_positions": 38, "similar_positions": 111, "identity": "7.27%" }, { "cls_id": "homologset.agr.SGD:S000006068", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QY44-1", "uniprot_id": "ABCD2_RAT", "id": "Q9QY44-1", "name": "ATP-binding cassette sub-family D member 2", "aln": "---------------------------------------------MIHMLNAAAYR---------VKWTRSGAAKRAACLVAAAYALKTLYPILGRRLKQPGHRKAKA---------------------EDYPPAENRERLHCTEIICKKPA----------------------------PGLNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFLSIYVAGLDGKIVKSIVEKKPRTFIIKLVKWLMIAVPATFVNSAIRYLECKLALAFRTRLVDHAYETYFANQTYYKVINMDGRLA-----NPDQSLTEDIMMFSQSVAHLYSNLTKPILDVILTSYTLIRTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGTLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMKQLQKCYKALAYQMNLILSKRLWYIMIEQFLMKYVWSGCGLIMVAIPIITATGFADGDLEDGPKQAM-------VSDRTEAFTTARNLLASGADAIERIMSSYKEITELAGYTARVYNMFWVFDEVKRGIYKRT--VTQEPENNSKSRGGLELPLSDTL---AIKGTVIDVDHGILCENVPIITPAG----------------------------------EVVASSLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYE--GVLYKPPPQH----MFYIPQRPYMSLG-SLRDQVIYPDSVDDMHEKGYTDRDLEHILHSVHLYHIVQ---REGGWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAIGAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRLNELCKILGEDSVLKTIQTAE--------DTS--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61285-1", "uniprot_id": "ABCD2_MOUSE", "id": "Q61285-1", "name": "ATP-binding cassette sub-family D member 2", "aln": "---------------------------------------------MIHMLNAAAYR---------VKWTRSGAAKRAACLVAAAYALKTLYPIIGKRLKQPGHRKAKA---------------------EAYSPAENREILHCTEIICKKPA----------------------------PGLNAAFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFLSIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIPATFVNSAIRYLECKLALAFRTRLVDHAYETYFANQTYYKVINMDGRLA-----NPDQSLTEDIMMFSQSVAHLYSNLTKPILDVILTSYTLIRTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGSLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMKQLQKCYKALAYQMNLILSKRLWYIMIEQFLMKYVWSSCGLIMVAIPIITATGFADGDLEDGPKQAM-------VSDRTEAFTTARNLLASGADAIERIMSSYKEITELAGYTARVYNMFWVFDEVKRGIYKRT--VTQEPENHSKRGGNLELPLSDTL---AIKGTVIDVDHGIICENVPIITPAG----------------------------------EVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYE--GVLYKPPPQH----MFYIPQRPYMSLG-SLRDQVIYPDSADDMREKGYTDQDLERILHSVHLYHIVQ---REGGWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAIGAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRLNELCKILGEDSVLKTIQTAE--------KTS--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBJ2-1", "uniprot_id": "ABCD2_HUMAN", "id": "Q9UBJ2-1", "name": "ATP-binding cassette sub-family D member 2", "aln": "---------------------------------------------MTHMLNAAADR---------VKWTRSSAAKRAACLVAAAYALKTLYPIIGKRLKQSGHGKKKA---------------------AAYPAAENTEILHCTETICEKPS----------------------------PGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFLSIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIPATFVNSAIRYLECKLALAFRTRLVDHAYETYFTNQTYYKVINMDGRLA-----NPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLTSYTLIQTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGLIMVAIPIITATGFADG--EDGQKQVM-------VSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYTARVYNMFWVFDEVKRGIYKRTA-VIQESESHSKNGAKVELPLSDTL---AIKGKVIDVDHGIICENVPIITPAG----------------------------------EVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYE--GVLYKPPPQH----MFYIPQRPYMSLG-SLRDQVIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQ---REGGWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAKGAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRLNELCKILGEDSVLKTIKNED--------ETS--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48410-1", "uniprot_id": "ABCD1_MOUSE", "id": "P48410-1", "name": "ATP-binding cassette sub-family D member 1", "aln": "------------------------------------------------MPVLSTP----------RPSRVTTLKRTAVVLALTAYGVHKIYPLVRQCLTPARGPQVP----------------------------AGEPTQEASGATATKA------------------------------GMNRVFLQRLLALLRLLFPRVLCRETGLLALHSAALVSRTFLSVYVARLDGRLARCIVRKDPRAFSWQLLQWLLIALPATFINSAIRYLEGQLALSFRSRLVAHAYGLYFSQQTYYRVSNMDGRLR-----NPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVANSEEIAFYGGHEVELALLQHSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAVPIITATGYAESDSEAMKKAALEMKEEELVSERTEAFTIARNLLTAAADATERIMSSYKEVTELAGYTARVYEMFQVFEDVKHCRFKRTG-DLEEAQAGPGVMVQSGVHVEGPL---KIQGQVVDVEQGIICENIPIITPTG----------------------------------EVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTYS--GVLYKPPPQR----MFYIPQRPYMSVG-SLRDQVIYPDSAEDMRRKGCSEQQLEAILGIVHLRHILQ---REGGWEAVCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIPKMQGRLQELRQILGEAAAPVQPLVP---------GVPT-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZHR2-1", "uniprot_id": "ABCD1_RAT", "id": "D3ZHR2-1", "name": "ATP-binding cassette sub-family D member 1", "aln": "------------------------------------------------MPVLSTPS---------RPSRVTTLKRTAVVLALTAYGVHKIYPLVRQCLTPARGPQVP----------------------------AGESTQEASGATTAKA------------------------------GMNRVFLQRLLVLLRLLFPGVLCRETGLLALHSAALVSRTFLSVYVARLDGRLARCIVRKDPRAFSWQLLQWLLIALPATFINSAIRYLEGQLALSFRSRLVAHAYGLYFSQQTYYRVSNMDGRLR-----NPDQSLTEDMVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVANSEEIAFYGGHEVELALLQHSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAVPIITATGYAESDSEAMKKAALEMKEEELVSERTEAFTIARNLLTAAADATERIMSSYKEVTELAGYTARVYEMFQVFEDVQHCRFKRTG-DLEEAQAGPGSMVHSGVHIEGPL---KIQGQVVDVEQGIICENIPIITPTG----------------------------------EVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTYS--GVLYKPPPQR----MFYIPQRPYMSVG-SLRDQVIYPDSAEDMRRKGCSEQQLEAILGIVHLRHILQ---REGGWEAVCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGISLLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIPKMQGRLQELRQILGEAAAPVQPLVP---------GIPT-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P33897-1", "uniprot_id": "ABCD1_HUMAN", "id": "P33897-1", "name": "ATP-binding cassette sub-family D member 1", "aln": "------------------------------------------------MPVLSRP----------RPWRGNTLKRTAVLLALAAYGAHKVYPLVRQCLAPARGLQAP----------------------------AGEPTQEASGVAAAKA------------------------------GMNRVFLQRLLWLLRLLFPRVLCRETGLLALHSAALVSRTFLSVYVARLDGRLARCIVRKDPRAFGWQLLQWLLIALPATFVNSAIRYLEGQLALSFRSRLVAHAYRLYFSQQTYYRVSNMDGRLR-----NPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVANSEEIAFYGGHEVELALLQRSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAVPIITATGYSESDAEAVKKAALEKKEEELVSERTEAFTIARNLLTAAADAIERIMSSYKEVTELAGYTARVHEMFQVFEDVQRCHFKRPR-ELEDAQAGSGTIGRSGVRVEGPL---KIRGQVVDVEQGIICENIPIVTPSG----------------------------------EVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTYG--GVLYKPPPQR----MFYIPQRPYMSVG-SLRDQVIYPDSVEDMQRKGYSEQDLEAILDVVHLHHILQ---REGGWEAMCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIPKMQRRLQELCQILGEAVAPAHVPAPSPQGPGGLQGAST-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RBC8-1", "uniprot_id": "ABCD1_DANRE", "id": "F1RBC8-1", "name": "ATP-binding cassette sub-family D member 1", "aln": "------------------------------------------------MSVYSKL----------PSQLKKPLVKKAVVLLIALYGVKKLSPYFFGKLKGRTSKQVKG---------------------ADPLTSNGEPLVEAARKRKRSP------------------------------AVNREFFDRLIRLLKILFPRLFCKELGLLGFHSLALISRTFLSIYVANLDGQIVKTIVKKDPRAFVVELTKWLLIAIPATFVNSAIRYLEGQLTLAFRTRLVTHAYMLYFSDQTYYRVSNMDGRLA-----NPDQSLTEDVVMFAASVAHLYSNLTKPILDVVVTCYTLIKTAESKGANTTWPSVIAGIVVALTAKVLRAFSPRFGKLVAEEARRKGDLRYMHSRIIANSEEIAFYGGHKIEMLQLQRSYNSLSRQINLILFKRLWYVMLEQFLMKYLWSASGLVMVAVPIITATGYSKYDSEDVKQAALDMKEEDLVSERTQAFTTARSLLNAAADAVERIMVSYKEVTELAGYTARVYEMFEVFEDVRDGVYRRSATEVKPEETGAPQNVTHGMRVEGPL---QIRGQVIDVEQGIKCENLPIITPTG----------------------------------DVVVSSLNMQVDEGMHLLITGPNGCGKSSLFRILSGLWPVYS--GVLYKPSPDH----MFYIPQRPYMSVG-TLRDQVIYPHSVQEMQEKGITDRQLEEILQTVSLRYILE---REGGWDAVSDWKDVLSGGEKQRMGMARMFYHKPQYALLDECTSAVSIDVEGKIFEAAKDAGISLLSITHRPSLWKYHSHLLQFDGEGGWRFEKLDASTRISLQDEKIRLETQLSGIPKMQQRLTELCRILGEDSSLPTPGDEEEDEEEDEKQTERDVQSAGKEKDLME", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7JUN3-1", "uniprot_id": "ABCD1_DROME", "id": "Q7JUN3-1", "name": "ATP-binding cassette sub-family D member 1", "aln": "------------------------------------------------MSVLSKYVDRIAEKCEHNGFTKHAFSYALVTSAILALTIKVTIPYVKNVNTTSSVRTQKGKTNGQLSPS------TRDSSEEDFKLAEAEKLLVAQQLKKKATNNLV------------------------EPGLNKEFLKHLQMLAKIMIPQAFCYETGLLSVHTFCLISRTFLSIYVAALEGALVKFIVRKDIKQFALVLLKWFGIAIPATFVNSMIRFLESKLSLAFRTRLVRHSYRLYFKNQNYYRVSNLDGRIE-----NADHRLTEDISVFANSVAHLYSSLTKPCFDLMLIGLALMRSSKKMKANIITGPALSIGVIALTAHILRIVSPKFGQLVSEEANRYGYLRHIHSRIITNAEEIAFYGGHKVEMQQLRQAYNRLVNQMTTIFNQKLWFIMLEQFFMKYVWSGTGMIMVSLPILTGSDVGLGTVPNTAISESR------VSERTQYLTTARNLLISAADAIERLMSSYKEIVSLAGYTFRVAGMMDVFEETALGVYCKTS-VMESNQSNGIIEFRNGKPIAKGR---IIYSDDP-KNMSISLRAVPVVTPNC----------------------------------DIVVPKLTLCIEPGVHLLITGPNGCGKSSLFRILSGLWPIYA--GELHIPRPVKDVPCMFYIPQRPYMSIG-SLCDQIIYPDTREDMKRKHITENELRSILKMVSLEHIAQ---RDS-FDVVRDWKDILSGGEKQRMAIARLFYHRPRYALLDECTSAVSIDVESSIYEIAKGMGITLLTITHRPTLWKYHTHILEFDGLGNWQFRKMNSDE-----EQKGQFLS---------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P16970-1", "uniprot_id": "ABCD3_RAT", "id": "P16970-1", "name": "ATP-binding cassette sub-family D member 3", "aln": "------------------------------------------------MAAFSKY------------LTARNSSLAGAAFLLFCLLHKRRRALGLHGKKSGKPPLQN------------------------------------NEKEGKKE----------------------------RAVVDKVFLSRLSQILKIMVPRTFCKETGYLILIAVMLVSRTYCDVWMIQNGTLIESGIIGRSSKDFKRYLFNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTRYLYEEYLQAFTYYKMGNLDNRIA-----NPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQGP------ASMMAYLLVSGLFLTRLRRPIGKMTIMEQKYEGEYRFVNSRLITNSEEIAFYNGNKREKQTIHSVFRKLVEHLHNFIFFRFSMGFIDSIIAKYIATVVGYLVVSRPFLDLAHPRHLHSTHSE--------------LLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNHGKYERTMVS--QQDKGIEGAQASPLIPGA--------GEIINADNIIKFDHVPLATPNG----------------------------------DILIQDLSFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFG--GHLTKPERGK----LFYVPQRPYMTLG-TLRDQVIYPDGKEDQKKKGISDQVLKGYLDNVQLGHILE---REGGWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEDYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYEFKKIT--------EDTVEFGS---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55096-1", "uniprot_id": "ABCD3_MOUSE", "id": "P55096-1", "name": "ATP-binding cassette sub-family D member 3", "aln": "------------------------------------------------MAAFSKY------------LTARNTSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQN------------------------------------NEKEGKKE----------------------------RAVVDKVFLSRLSQILKIMVPRTFCKETGYLLLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSSKDFKRYLFNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTRYLYEEYLQAFTYYKMGNLDNRIA-----NPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQGP------ASMMAYLLVSGLFLTRLRRPIGKMTIMEQKYEGEYRYVNSRLITNSEEIAFYNGNKREKQTIHSVFRKLVEHLHNFIFFRFSMGFIDSIIAKYVATVVGYLVVSRPFLDLAHPRHLHSTHSE--------------LLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNHGRYERTMVS--QQEKGIEGAQASPLVPGA--------GEIINTDNIIKFDHVPLATPNG----------------------------------DILIQDLSFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFG--GRLTKPERGK----LFYVPQRPYMTLG-TLRDQVIYPDGKEDQKKRGISDQVLKEYLDNVQLGHILE---REGGWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEDYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYEFKKIT--------EDTVEFGS---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28288-1", "uniprot_id": "ABCD3_HUMAN", "id": "P28288-1", "name": "ATP-binding cassette sub-family D member 3", "aln": "------------------------------------------------MAAFSKY------------LTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQN------------------------------------NEKEGKKE----------------------------RAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDNRIA-----NPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQGP------ASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHPRHLKSTHSE--------------LLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNHGKYERTMVS--QQEKGIEGVQVIPLIPGA--------GEIIIADNIIKFDHVPLATPNG----------------------------------DVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFG--GRLTKPERGK----LFYVPQRPYMTLG-TLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILE---REGGWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYEFKQIT--------EDTVEFGS---------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PXC6-1", "uniprot_id": "A0A8M9PXC6_DANRE", "id": "A0A8M9PXC6-1", "name": "ATP-binding cassette sub-family D member 3", "aln": "------------------------------------------------MAAVSKY------------LTAKNSAVAGGVLLVLYILKQRRRAAALNRKK-GSANELN------------------------------------SEKDGKKE----------------------------RAAVDKLFFIRISRILKIMVPKFFSKETWYLLLIAVMLVTRTYCDVWMIQNGTMIESGIISRDIKLFKRHFYSYLTVIPGIALVNNFLKLGLNELKLCFRVRLTKHLYDEYLKGYTYYKMGNLDNRIA-----NADQLLTQDVERFCNSVVDLYSNLSKPLLDIGLYIFKLTTAIGAQGP------ATMMAYLLISGLFLTRLRRPIGKMTVTEQKYEGEYRYVNSRLITNSEEIAFYNGNTREKQTIHSTFKKLVDHLHNFIFFRFSMGMVDSIIAKYFATVVGYLVVSRPFLNLSHSRHLNSSHAE--------------LLEDYYQSGRMLLRMSQALGRIVLAGREMTRLSGFTARITELMRVLKELNSGKYERTMVS--QSEK--DASEKLTLVPGS--------GRIINIDNIIKFDHTPLATPNG----------------------------------DVLIRDLCFEVKSGTNVLVCGPNGCGKSSLFRVLGELWPLFG--GNLTKPERGK----LFYVPQRPYMTLG-SLRDQVIYPDTHESQKKKGISDLVLKEYLDNVQLGHILD---REGSWDTVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEDYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYEFKPIT--------PETVEFGS---------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWC8-1", "uniprot_id": "Q9VWC8_DROME", "id": "Q9VWC8-1", "name": "ATP-binding cassette sub-family D member 3", "aln": "------------------------------------------------MAPALSK------------LANNQSAIVGVAGMTAALWIIAYGKMSNKKRKPGYEDKIQY---------------------------------TIAEKKDKKAG---------------------------KAHVNSVFFKQLRQLLPILIPGFWSVETGLLFLVAAALIGRSVSDIWMIQNATVVESTIIHMNRTKFKTALLKYLTALPAISVVTNVLKWSLGELKLRFRTNLTHHLYSQYLNGYTYYKMSNLDNRIA-----NADQLLTTDIDKFCESATDLYSNISKPVLDIFIYVYRLTVNLGGKTP------SILMLYLLFAGVFLTRLRRPTGRLTVEEQKLEGEFRYVNSRLITNSEEVAFYQGNVREKLTLLASYSKLRSHLRKFLEFRVSMGIIDNIIGKYFASIVGFYAVSIPFFSENHPLLSGENSGQ--------------RLQAYYTYGRMLVKLAEAIGRLVLAGREMSRLAGFTARMTELIKVLSDLNKGTYERTMVNGNNLAQNAVGSASSNFGPNK--------GIMCFEDNIIRFEKVPLVTPNG----------------------------------DVLLQELSFEVKSGTNVLVCGPNGCGKSSLFRILGELWPTWG--GKVTKPSRGK----LFYVPQRPYMTLG-TLRDQIIYPHTRDDMRRLGHSDEDLMHYLDIVQLTYLEQ---RENGLDSIEDWIDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGKMYSYCREVGITLFTVSHRKSLWAHHDYYLQFDGRGSYEFATID--------QDKDHFGS---------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41909-1", "uniprot_id": "PXA1_YEAST", "id": "P41909-1", "name": "Peroxisomal long-chain fatty acid import protein 2", "aln": "MSTTLAAPAKLKSLLLNLHTHCIGLHVNDVTPKVYFKLLIRHLLQISRSNAAHPKLRRRAQILLVSLFLSGVTLFSGVTYSTFKIILKCYKFYKFPWKRRNRRPLIRRTRSQMQLDSGARIMYIPEVELVDRQSPDDNKFMNATDKKKRKRIFIPPKDNDVYEHDKFLFKNVELERAKNSQLFYSKFLNQMNVLSKILIPTVFDKNFLLLTAQIFFLVMRTWLSLFVAKLDGQIVKNIIAGRGRSFLWDLGCWFLIAVPASYTNSAIKLLQRKLSLNFRVNLTRYIHDMYLDKRLTFYKLIFDAKASNSVIKNIDNSITNDVAKFCDATCSVFANIAKPVIDLIFFSVYLRDNLGTVGVAG------IFVNYFITGFILRKYTPPLGKLAGERSASDGDYYNYHLNMINNSEEIAFYQGTAVERTKVKELYDVLMEKMLLVDKVKFGYNMLEDYVLKYTWSGLGYVFASIPIVMSTLATGINSEEKN---------------MKEFIVNKRLMLSLADAGSRLMHSIKDISQLTGYTNRIFTLLSVLHRVHSLNFNYGAVPSILSIRTEDASRNSNLLPTTDNSQDAIRGTIQRNFNGIRLENIDVIIPSVRASEGIKLINKLTFQIPLHIDPITSKSNSIQDLSKANDIKLPFLQGSGSSLLILGPNGCGKSSIQRIIAEIWPVYNKNGLLSIPSENN----IFFIPQKPYFSRGGTLRDQIIYPMSSDEFFDRGFRDKELVQILVEVKLDYLLKRGVGLTYLDAIADWKDLLSGGEKQRVNFARIMFHKPLYVVLDEATNAISVDMEDYLFNLLKRYRFNFISISQRPTLIKYHEMLLEIGENRDGKWQLQAVGTDEAITSIDNEIEELERKLERVKGWEDERTKLREKLEII--------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *: :: : ::.* : * *: *: .::: : *: * : :: : .. :: :* * ** .*. : : *: : :* : * *: :* *: *. :. :::.::** :*: . * :. .* * :. . * : .:: * **:*** * * : : * :: . :. :::. . ** : * .: *:. : :: ::* *:: : ::: *:*:* *: :: *: : . * : * . * : * :*: *********: *::. :** : * : * . :*::**:**:: * :* **:*** :. : * * * * :: . : : ** *:********: :**:::*:* :.:***.*.*:*:*:*. ::. : ::::::* :* :* *.:. . .: .: ", "identical_positions": 108, "similar_positions": 161, "identity": "11.65%" }, { "cls_id": "homologset.agr.SGD:S000006070", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3MQ06-1", "uniprot_id": "ATG5_RAT", "id": "Q3MQ06-1", "name": "Autophagy protein 5", "aln": "--MTDDKDVLRDVWFGRIPTCFTLYQDEITEREAEPYYLLLPRVS-------YLTLVTDKVKKHFQKVMRQEDVS-EIWFEYEGTPLKWHYPIGLLFDLLASS-SALPWNIT--------------VHFKSFPEKDLLHCPCKDAVEAHFMSCVKEADALKHKS-QVINEMQRKDHKQLWMGLQNDRFDQFWTINRKLMEYPPEENGFRYIPFRIYQTTTERPFIQKLFRPVAADGQLHTLGDLLREVCPSAVAPEDGEKKSQVMIHGIEPLLETPLQWLSEHLSYPDNFLHISIVPQPTD-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J83-1", "uniprot_id": "ATG5_MOUSE", "id": "Q99J83-1", "name": "Autophagy protein 5", "aln": "--MTDDKDVLRDVWFGRIPTCFTLYQDEITEREAEPYYLLLPRVS-------YLTLVTDKVKKHFQKVMRQEDVS-EIWFEYEGTPLKWHYPIGLLFDLLASS-SALPWNIT--------------VHFKSFPEKDLLHCPSKDAVEAHFMSCMKEADALKHKS-QVINEMQKKDHKQLWMGLQNDRFDQFWAINRKLMEYPPEENGFRYIPFRIYQTTTERPFIQKLFRPVAADGQLHTLGDLLREVCPSAVAPEDGEKRSQVMIHGIEPMLETPLQWLSEHLSYPDNFLHISIVPQPTD-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1Y0-1", "uniprot_id": "ATG5_HUMAN", "id": "Q9H1Y0-1", "name": "Autophagy protein 5", "aln": "--MTDDKDVLRDVWFGRIPTCFTLYQDEITEREAEPYYLLLPRVS-------YLTLVTDKVKKHFQKVMRQEDIS-EIWFEYEGTPLKWHYPIGLLFDLLASS-SALPWNIT--------------VHFKSFPEKDLLHCPSKDAIEAHFMSCMKEADALKHKS-QVINEMQKKDHKQLWMGLQNDRFDQFWAINRKLMEYPAEENGFRYIPFRIYQTTTERPFIQKLFRPVAADGQLHTLGDLLKEVCPSAIDPEDGEKKNQVMIHGIEPMLETPLQWLSEHLSYPDNFLHISIIPQPTD-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RDC0-1", "uniprot_id": "F1RDC0_DANRE", "id": "F1RDC0-1", "name": "Autophagy protein 5", "aln": "MIMADDKDVLRDVWFGRIPACFTLSPDETTEREAEPYYLLLPRVS-------YLTLVTDKVKKHFLKVMKAEDVE-EMWFEHEGTPLKWHYPIGVLFDLHASN-SALPWNIT--------------VHFKNFPEQDLLHCSTNSVIEAHFMSCIKEADALKHKG-QVINDMQKKDHKQLWMGLQNDKFDQFWAMNRKLMEYPTEEGGFRYIPFRIYQTMSDRPFIQTLFRPVSSEGQALTLGDLLKELFPAAIE--DEPKKFQVMIHGIEPLLETPIQWLSEHLSHPDNFLHISIIPAPSD-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3R7-1", "uniprot_id": "ATG5_DROME", "id": "Q9W3R7-1", "name": "Autophagy protein 5", "aln": "--MAHDREVLRMIWEGQIGICFQADRDEIVGIKPEPFYLMISRLS-------YLPLVTDKVRKYFSRYISAEHQDGAVWFDFNGTPLRLHYPIGVLYDLLHPEEDSTPWCLT--------------IHFSKFPEDMLVKLNSKELLESHYMSCLKEADVLKHRG-LVISAMQKKDHNQLWLGLVNEKFDQFWAVNRRLMEPYGDLESFKNIPLRIY-TDDDFTYTQKLISPISVGGQKKSLADLMAELSTPVR------RAVGCRTHGIDLHEETQLQWMSEHLSYPDNFLHLSVDYKDV--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12380-1", "uniprot_id": "ATG5_YEAST", "id": "Q12380-1", "name": "Autophagy protein 5", "aln": "-----MNDIKQLLWNGELNVLVSIDPSFLMKGSPREIAVLRIRVPRETYLVNYMPLIWNKIKSFLSFDPLTDSEK-YFWFEHNKTPIPWNYPVGVLFDCLAGKSATFTTSFENQVKDVLTFLRIHLVMGDSLPPTIIPIASSKTQAEKFWFHQWKQVCFILNGSSKAIMSLSVNEARKFWGSVITRNFQDFIEISNKISSSRP-----RHIPLIIQTSRTSGTFRISQP-TISMTGVNPTLKDIEGDILDVKEG--INGNDVMVICQGIEIPWHMLLYDLYSKLRSFDGFLYITLVPIKGGDKASSEL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: : :* *.: . . ... :: *:. *:.*: :*::..: : . .**:.: **: :**:*:*:* . : . : : ..:* : : * .:: *:. : : . .* :. :: .::* .: . .*::* :..:: . : **: * : . .: . .:: * :* *: :: . :**: . : : .:* *.**:::: ", "identical_positions": 34, "similar_positions": 101, "identity": "11.04%" }, { "cls_id": "homologset.agr.SGD:S000006071", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61846-1", "uniprot_id": "MELK_MOUSE", "id": "Q61846-1", "name": "Maternal embryonic leucine zipper kinase", "aln": "------------------------------MKDYDELLKYYELYETIGTGGFAKVKLACHVLTGEMVAIKIMDKNALGSDLPRVKTEIDALKSLRHQHICQLYHVLETKNKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQILSAVAYVHSQGYAHRDLKPENLLFDENHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDN-VMALYKKIMRGKYEVPKWLSPSSILLLQQMLQVDPKKRISMRNLLNHPWVMQDYSCPVEWQSKTPLTHLDEDCVTELSVHHRSSR---------QTMEDLISSWQYDHLTATYLLLLAKKARGKPARLQLLSFSCGTASTTP----KSKNLSLEDMSTSDDNCVAG--LIDYELCEDKLLA----PKTPQVT------------KHLAESNHAASKSPAPGVRRAVANKL-------MDKENVCTPKSSVKNEEQFVFSEPKIPVS----------KNQYKREIPASP----TRFPTPAKARAQCLREAPVRTPGNSAG-------------------------------------ADTLTTGVISPERRCRSMDVDLNQAHMEDTPK---------------------------------------KKGTNVFGSLERGLDKVLT---------ALTRNKKKGSARDGPRKRKLHYNVTTTR--------------------------------------------------------LVNPDQLLSEIMAILPKKNVDFVQKGYTLKCQTQSDFGKVT-------------------------MQFELEVCQLQ----RPDVVGIRRQRLKGDAWVYKRLVEDILSGCKM------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14680-1", "uniprot_id": "MELK_HUMAN", "id": "Q14680-1", "name": "Maternal embryonic leucine zipper kinase", "aln": "------------------------------MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDN-VMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNR---------QTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLRLSSFSCGQASATPFTDIKSNNWSLEDVTASDKNYVAG--LIDYDWCEDDLSTGAATPRTSQFT------------KYWTESNGVESKSLTPALCRTPANKL-------KNKENVYTPKSAVKNEEYFMFPEPKTPVN----------KNQHKREILTTP----NRYTTPSKARNQCLKETPIKIPVNSTG-------------------------------------TDKLMTGVISPERRCRSVELDLNQAHMEETPK---------------------------------------RKGAKVFGSLERGLDKVIT---------VLTRSKRKGSARDGPRRLKLHYNVTTTR--------------------------------------------------------LVNPDQLLNEIMSILPKKHVDFVQKGYTLKCQTQSDFGKVT-------------------------MQFELEVCQLQ----KPDVVGIRRQRLKGDAWVYKRLVEDILSSCKV------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QGZ6-1", "uniprot_id": "MELK_DANRE", "id": "F1QGZ6-1", "name": "Maternal embryonic leucine zipper kinase", "aln": "----------------------------MPVDSTSELLKHYEVYETIGSGGFAKVKLGRHKLTGEKVAIKIMEKKDLGDDLPRVKIEIEAMKNLSHQHVCRLYHVIETTSKIYMVLEYCPGGELFDYIIAKDRLSEEETRVFFRQIISALAYVHSQGYAHRDLKPENLLIDEDHNLKLIDFGLCAKPKGGLGFELLTCCGSPAYAAPELIQGKAYIGSEADVWSMGVLLYALLCGFLPFDDDN-CMVLYRKITRGKYSNPHWLSPSSILLLNQMMQVDPKRRLTVKHLLDHPWVMRGYSTPVEWHSKYPLGHIDEDCITEMAVTFKQSK---------QRTIQLVSEWKYDQITATYLLLLAKKRQGRPVRLRAECPVIDIVCSPLQDMQLKKSLRFTEDDDGVHPVVLGSMVFPPDCYDDENPWTPLTPKNTHTTNTPRMKLYPETTEKWNEMAYSPVIEHSRPCRQKPERRE-------RTKENKENLAVPGTDGDVFALPAPRTPTSS--------RKVKSNRTVMTTPNHNNNKSSEVNKGAGSATKEGSRRREVEQQQNG----------------------------------QQGELNILAFSPERRSRS--LDLAGCQVDSGQK---------------------------------------RKGGKVFGSLERGLDKVIT---------MLTPSKKRG-PRDGPRKIKAQYNVTLTN--------------------------------------------------------QTNADQVLNQILSILPEKNVDFVQKGYTLKCHTQSDFGKVT-------------------------MQFELEVCLLQ----KPEVVGIRRQRLKGDAWVYKHLVEDILSSSSQWSA---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12152-1", "uniprot_id": "YP150_YEAST", "id": "Q12152-1", "name": "Putative serine/threonine-protein kinase YPL150W", "aln": "MVNPVGSSKLEQNNIKSIIGSSYNRLYSQFTSDELTEVGNYKILKQIGEGSFGKVYLALHRPTHRKVCLKTSDKN-----DPNIVREVFYHRQFDFPYITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTR--ECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIPDDARDLISRLLAKNPGERPSLSQVLRHPFLQPYGSVVLDQTQKILCRQRSGGTQFKSKLERRLLKRLKQSGVDTQAIKQSILKKKCDSLSGLWLLLLAQGKKQENCKYPKRSRSVLSVKKVIESATHNDTNGISEDVLKPSLELSRAASLSKMLNKGSDFVTSMTPVSRKKSKDSAKVLNPTLSKISSQRAYSHSIAGSPRKSNNFLQKVSSFFKSKKSSNSNSNNSIHTNVSESLIASNRGAPSSGSFLKKNSGSIQKSRTDTVANPSRTESIGSLNENVAGAIVPRSANNTTLENKKTSGNEIGLKVAPELLLNEHIRIEEPRLKRFKSSISSEISQTSTGNYDSESAENSRSISFDGKVSPPPIRNRPLSEISQISNDTYISEYSTDGNNSSFKISDTIKPSYIRKGSETTSQYSASSEKMTNGYGRKFVRRDLSIVSTASSTSERSSRTDSFYDITTATPVVTTDNRRNKNNNLKESVLPRFGTQRPWTGKRTYTTSRHGKNARRSSKRGLFKITSSNTDSIIQEVSSSEEEDHNVIYSKGKGLPTPVLQTKGLIENGLNERDEEGDDEYAIHTDGEFSIKPQFSDDVIDKQNHLPSVKAVATKRSLSEGSNWSSSYLDSDNNRRRVSSLLVEDGGNPTA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : *:: : ** *.*.** *. * * . *.:* :*: *.: *: :.: . :: :**.*: * .*::*.****** **:*:::: *:* * .* ** .*: *.** .***** **:*:*: : ** ***: : * * **: .* *****: ::* * : *:**:*::**.*: *:******: . :: : . .: :. .: *:.::: :* .* :: ::* **:: . :: .* : . . : : : : * : : : * ::. :*****: : . : . . ... : : : : ... * . : : : : : . .: .:. . . : : . * . : . :.* . . : . . . :. . ..* .* :.: : :** :. .. . . :*: . *: . . . : . : . *::* : *.*.::.:: : :.: : .** * . . * : **. :* * ..*. :*. :*. * . * .* ", "identical_positions": 121, "similar_positions": 205, "identity": "13.33%" }, { "cls_id": "homologset.agr.SGD:S000006072", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUC8-1", "uniprot_id": "PLRG1_RAT", "id": "Q9WUC8-1", "name": "Pleiotropic regulator 1", "aln": "-MVEEVQKHSVHTL----VFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPTSK-ENLKEKGPQNAPDSYPHKQYPANQGQDVEYLVTGTHPYPPGPGVALTADTKIQRMPSESAAQSLAVALPSQTRVDANRTAPAGSEYRHPGASDRSQPTAMNSMIMETSNTKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEP-GNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPLHYTFASGSPDNIKQWKFPDGGFIQNLSG-HNAIINTLAVNTDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDRSESRLLTAEADKTIKVYREDETATEETHP-VSWKPEIIKRKRF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q922V4-1", "uniprot_id": "PLRG1_MOUSE", "id": "Q922V4-1", "name": "Pleiotropic regulator 1", "aln": "-MVEEVQKHSVHTL----VFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPTSK-ENLKEKGPQNATDSYPHKQYPANQGQDVEYLVTGTHPYPAGPGVALTADTKIQRMPSESAAQSLAVALPSQTRVDANRTGPAGSEYRHPGASDRSQPTAMNS-IMETGNTKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEP-GNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTLDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPLLYTFASGSPDNIKQWKFPDGGFIQNLSG-HNAIINTLAVNADGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDRSESRLLTAEADKTIKVYREDETATEETHP-VSWKPEIIKRKRF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43660-1", "uniprot_id": "PLRG1_HUMAN", "id": "O43660-1", "name": "Pleiotropic regulator 1", "aln": "-MVEEVQKHSVHTL----VFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPTSK-ENLKEKGPQNATDSYVHKQYPANQGQEVEYFVAGTHPYPPGPGVALTADTKIQRMPSESAAQSLAVALPLQTKADANRTAPSGSEYRHPGASDRPQPTAMNSIVMETGNTKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEP-GNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSG-HNAIINTLTVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVYREDDTATEETHP-VSWKPEIIKRKRF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYQ9-1", "uniprot_id": "Q9VYQ9_DROME", "id": "Q9VYQ9-1", "name": "Pleiotropic regulator 1", "aln": "MAMEDVQKHSVHTL----IFRSLKRTHDLFVSNQGNLPEIDERLEKLRRSIKAKDGYGLVLDKVAKIGEARKASGAQTPGD----KTLAITDG--------SATDAASGAGSLVKYNAGAR--PAEKTAP-----LVTGTHTSLVRASLANS------NADMSANGAIAS---------HLQLIPKKAPSIPKPKWHAPWKLSRVISGHLGWVRCIAVEP-GNEWFATGAGDRVIKIWDLASGKLKLSLTGHVSTVRGVAVSTKHPYLFSCGEDRQVKCWDLEYNKVIRHYHGHLSAVYSLALHPTIDVLATSGRDSTARIWDMRTKANVHTLTGHTNTVASVVAQATNPQIITGSHDSTVRLWDLAAGKSVCTLTNHKKSVRSIVLHPSLYMFASASPDNIKQWRCPEGKFVQNISG-HTSIVNCMAANSEGVLVSGGDNGTMFFWDWRTGYNFQRFQAPVQPGSMDSEAGIFAMCFDQSGSRLITAEADKTIKVYKEDDEASEESHP-INWRPDLLKRRKF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12417-1", "uniprot_id": "PRP46_YEAST", "id": "Q12417-1", "name": "Pre-mRNA-splicing factor PRP46", "aln": "---MDGNDHKVENLGDVDKFYSRIRWNNQFSYMATLPPHLQSEMEGQKSLLMRYDTY-------------RKESSS------------------------------FSGEGKKVTLQHVPTDFSEASQAV------ISKKDHDTHASAFVNKIF----QPEVAEELIVNR---------YEKLLSQ------RPEWHAPWKLSRVINGHLGWVRCVAIDPVDNEWFITGSNDTTMKVWDLATGKLKTTLAGHVMTVRDVAVSDRHPYLFSVSEDKTVKCWDLEKNQIIRDYYGHLSGVRTVSIHPTLDLIATAGRDSVIKLWDMRTRIPVITLVGHKGPINQVQCTPVDPQVVSSSTDATVRLWDVVAGKTMKVLTHHKRSVRATALHPKEFSVASACTDDIRSWGLAEGSLLTNFESEKTGIINTLSINQDDVLFAGGDNGVLSFYDYKSGHKYQSLATREMVGSLEGERSVLCSTFDKTGLRLITGEADKSIKIWKQDETATKESEPGLAWNPNLS-AKRF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.*.*..* * * * :: * ::.. . : : : * * ... .* * :. : . . * . . :. .. .: . : *:.: :*:**.**** ***.********:*::* .*:** **: * .:*:****:**** :*:**: ***.* ** : ***** .**: ******* *::**.*:****.* : :***:*::.*..***. ::**:**: * ** **...: * . ..:**:::.* *:*:****:.***: .**:**:***: .*** : .**...*:*:.* .:* :: *:.. :..*:* :: * :.**.:*.***.: ::*:::*:::* . : **::.* .::. **:: **:*.****:**::::*: *::*:.* : *.*:: ::*", "identical_positions": 160, "similar_positions": 164, "identity": "30.59%" }, { "cls_id": "homologset.agr.SGD:S000006073", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LHB2-1", "uniprot_id": "A0ABK0LHB2_RAT", "id": "A0ABK0LHB2-1", "name": "Serine/threonine-protein phosphatase 2A activator", "aln": "MAEGERQPPPDSSEETPSATP--TFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLT-----FDYKV-----------------------------------SEAIEKLVALLDTLDRWIDETPP--VDQP--SRFGN---KAYRTWYAKLDQEAENLVATVIPTNLAAAVPEVAVYLKEAVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVD-DQVAIVFKVFDRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPHLEPRHFVDEKAVSENHKDYMFLQCILFITEMKTGP-FAEHSNQLWNISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTS--------------G-----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58389-1", "uniprot_id": "PTPA_MOUSE", "id": "P58389-1", "name": "Serine/threonine-protein phosphatase 2A activator", "aln": "MAEGERQPPPDSSEETPPTTQ--NFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLT-----FDYKV-----------------------------------SEAIEKLVALLDTLDRWIDETPP--VDQP--SRFGN---KAYRTWYAKLDQEAENLVATVVPTHLAAAVPEVAVYLKEAVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVD-DQVAIVFKVFDRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPHLEPRHFVDEKAVSENHKDYMFLQCILFITEMKTGP-FAEHSNQLWNISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTS--------------G-----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15257-1", "uniprot_id": "PTPA_HUMAN", "id": "Q15257-1", "name": "Serine/threonine-protein phosphatase 2A activator", "aln": "MAEGERQPPPDSSEEAPPATQ--NFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLT-----FEYRVSEMWNEVHEEKEQAAKQSVSCDECIPLPRAGHCAPSEAIEKLVALLNTLDRWIDETPP--VDQP--SRFGN---KAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVD-DQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGP-FAEHSNQLWNISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTS--------------G-----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2CF49-1", "uniprot_id": "A2CF49_DANRE", "id": "A2CF49-1", "name": "Serine/threonine-protein phosphatase 2A activator", "aln": "MAETEQASGSSHEDDKPPSSVGFNFMVPKKEISMVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLT-----CEYQV-----------------------------------SETVEKLLALLGTLDQWIDETPP--VDQP--SRFGN---KAFRTWYAKLDQEAEALVAGVLPAERQDAAPEIAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKVGALRME-DQLAIIFNVFDKYLRVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPTLEPRHFVEEKVVNEYHQDYMFLECIKFINEMKTGP-FAEHSNQLWNISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLSIQPVKP--------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12461-1", "uniprot_id": "PTPA2_YEAST", "id": "Q12461-1", "name": "Serine/threonine-protein phosphatase 2A activator 2", "aln": "-------------------------MLPEKRLLTPDDMKLWEESPTRAHFTKFIIDLAESVKGHENSQ---YKEP------------------------------------ISESINSMMNLLSQIKDITQKHPV--IKDADSSRFGK---VEFRDFYDEVSRNSRKILRSEFPSLTDEQLEQLSIYLDESWGNKRRIDYGSGHELNFMCLLYGLYSYGIFNLSNDSTNLVLKVFIEYLKIMRILETKYWLEPAGSHGVWGLDDYHFLPFLFGAFQLTTHKHLKPISIHNNELVEMFAHRYLYFGCIAFINKVKSSASLRWHSPMLDDISGVKTWSKVAEGMIKMYKAEVLSKLPIMQHFYFSEFLPCPDGVS--------------PPRGHIH------DGT--------------DKDDECN--FEGHVHTTWGDCCG----IKLPSAIAATEMNKKHHKPIPFD----------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VQQ0-1", "uniprot_id": "PTPA_DROME", "id": "Q9VQQ0-1", "name": "Serine/threonine-protein phosphatase 2A activator", "aln": "MASGINQAAG-------------KLPAIAKKVQNLGDMGVWQKSRAFHDLIGYINGTSSAIQGIKTT-----DEIFE-----------------------------------SEMLKKLLRLFDALEKLVEQNPP--LEQP--QRFGN---KAYRDWAQAMRELLPELLEQLLPDDKKRYQVELGQYLTESFGNATRIDYGTGHELSFLFFLCSLFKAEILQER-DIVSAALRLFNRYLELARQLQRTYNMEPAGSQGVWSLDDFQFVPFIWGSAQLAVKSPFDPSKFVDEAIITEYKDHFMFISCIDYICKVKTGH-FGEHSNQLWSITDVPTWAKINAGLVKMYQKEILSKFPVIQHVYFGELMTFEPVSSGTTLSNARLGHVAPPPSKRIC------IGTPNLVPPVPVATAPPPPAESLS--IEQNVGDSSSESSDNSVVLRPSTSSSSLVAAAEGSGDKPSKE---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNG7-1", "uniprot_id": "Q9VNG7_DROME", "id": "Q9VNG7-1", "name": "Serine/threonine-protein phosphatase 2A activator", "aln": "-----MEPQSEVNPKRVAAFFRRSNIGPVCRVQSSSDMEAWLASRAYFTLITYLNDVSAEIQGIRNTDLFP----------------------------------------ISKNIKRLTTIFEQLDSMIVANSP--APLVLGANMDSR-TKSYRRWAHGMLRDIYKIVEKAVPSSKCRHVNELGVYLSGSFGSSAKIEYGTGHELSFLFFVCALFKAEILDKEQDLAASALVLFDRYLHFVRRLQVTYSVNSSNWHGGYSLDKFQFVPFVWGFAQLCHEAPFSPKKMLDEDTIAKYRDAYMLINCVGHMATTNVGT-FARHSSQLWSLAALSSWTKIHRSLMFMYMEDILMDIDNLNALRFGELMSFEEDKSGRHLGSARMGVKSPLRRQMAEDPDDQDQDQDLTSRSGTPSISRSEQNDSAR--KKAKVEETSSDCMSNSGLSLGSECTSLSGVSVHLPTWLDDCTATSKNAF--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VXN8-1", "uniprot_id": "Q9VXN8_DROME", "id": "Q9VXN8-1", "name": "Serine/threonine-protein phosphatase 2A activator", "aln": "-MSNKLGYDVTDPTVQLLRASAFMQNGPVKQVRSLEDLDRWVRSQAYYDIIAYISNTSKAIQGHRLTQTFP----------------------------------------VTEQMRRLSEIFDGLDHLIVEHTPKIEDSYLALPFGQVRSKAYRTWMREMYQHVFSKLDEAINVN-CKHINELGQYLRRSFGNGNTLDFGPANELMFLFFLCGLFRAGILLAK-DTVAAALMLFNRYVNVVRRLISTYGLTIAKDP-ACTIEDYYFLPYLWGAAQLSVDSPFSPMQCEQGKIMDNYRQDFMMLEIIDHLQKTRSGP-LSRVALQLWSILSIPTWPQVYRGLERNYIDHVLSSFGTVEQAIFCELMSFEAVVPIMPLQRAHLGTHLIVDEKENEDELEQKYGENRWSLSPPVSRYVSMEPESFLGFQASKTHNKSKESEDERLWMMRQLVDENDPNSDMFFPDREVKGRDSLTSFAN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: *: * * : :: ::* . : :: :. : :: :. . :.. :* : : . : . ::. ** : *. :::*..:* * :: * : * : :* .*:.. * * .* : : ::.: *:*:::* ** . :.* : : . :: : : .: . . : : * .: : :*.:: .: * . * .: :: * .::. . ", "identical_positions": 29, "similar_positions": 95, "identity": "6.08%" }, { "cls_id": "homologset.agr.SGD:S000006075", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24268-1", "uniprot_id": "CATD_RAT", "id": "P24268-1", "name": "Cathepsin D", "aln": "-----MQTPGVLLLILGL-----LDASSSALIRIPLR---KFTSIRRTMTEVGGSVEDLILKGPI--------------------TKYSMQSSPRTKE-PVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCK--SDLG---GIKVEKQIFGEATKQPGVVFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPT---GQPGGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELT--LCKGGCEAIVDTGTSLLVGPVDEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILK----------------------VSQAGKTICLSGFMG-MDIPPPSGPLWILGDVFIGCYYTVFDREYN----RVGFAKAATL--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18242-1", "uniprot_id": "CATD_MOUSE", "id": "P18242-1", "name": "Cathepsin D", "aln": "-----MKTPGVLLLILGL-----LASSSFAIIRIPLR---KFTSIRRTMTEVGGSVEDLILKGPI--------------------TKYSMQSSPKTTE-PVSELLKNYLDAQYYGDIGIGTPPQCFTVVFDTGSSNLWVPSIHCKILDIACWVHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCK--SDQSKARGIKVEKQIFGEATKQPGIVFVAAKFDGILGMGYPHISVNNVLPVFDNLMQQKLVDKNIFSFYLNRDPE---GQPGGELMLGGTDSKYYHGELSYLNVTRKAYWQVHMDQLEVGNELT--LCKGGCEAIVDTGTSLLVGPVEEVKELQKAIGAVPLIQGEYMIPCEKVSSLPTVYLKLGGKNYELHPDKYILK----------------------VSQGGKTICLSGFMG-MDIPPPSGPLWILGDVFIGSYYTVFDRDNN----RVGFANAVVL--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07339-1", "uniprot_id": "CATD_HUMAN", "id": "P07339-1", "name": "Cathepsin D", "aln": "-----MQPSSLLPLALCL-----LAAPASALVRIPLH---KFTSIRRTMSEVGGSVEDLIAKGPV--------------------SKYSQAVPAVTEG-PIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPD---AQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLT--LCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLK----------------------VSQAGKTLCLSGFMG-MDIPPPSGPLWILGDVFIGRYYTVFDRDNN----RVGFAEAARL--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O09043-1", "uniprot_id": "NAPSA_MOUSE", "id": "O09043-1", "name": "Napsin-A", "aln": "-------MSPLLLLLLCL-LLGNLEPEEAKLIRVPLQ---RIHLGHRILNPLNG------WEQLA--------------------ELSRT--STSGGN-PSFVPLSKFMNTQYFGTIGLGTPPQNFTVVFDTGSSNLWVPSTRCHFFSLACWFHHRFNPKASSSFRPNGTKFAIQYGTGRLSGILSQDNLT-----------IGGIHDAFVTFGEALWEPSLIFALAHFDGILGLGFPTLAVGGVQPPLDAMVEQGLLEKPVFSFYLNRDSE---GSDGGELVLGGSDPAHYVPPLTFIPVTIPAYWQVHMESVKVGTGLS--LCAQGCSAILDTGTSLITGPSEEIRALNKAIGGYPFLNGQYFIQCSKTPTLPPVSFHLGGVWFNLTGQDYVIK----------------------ILQSDVGLCLLGFQA-LDIPKPAGPLWILGDVFLGPYVAVFDRGDKNVGPRVGLARAQSRSTDRAERRTTQAQFFKRRPG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FL28-1", "uniprot_id": "F7FL28_RAT", "id": "F7FL28-1", "name": "Napsin-A", "aln": "------MLPPPLLLLLCLVLLGNLEP-AATLIRVPLR---RIHPGHRIFSPLYG------WEQRA--------------------ELSRT--PTSGGK-TAFVPLSKFMNTQYFGDIGLGTPPQNFTVVFDTGSSNLWVPSTRCHFFSLACWFHHRFNPKASSSFRPNGTKFAIQYGTGRLSGILSRDNLT-----------IGGIHNVSVTFGEALWEPSLVFALARFDGILGLGFPTLAVGGVQPPLDALVEQRLLEKPVFSFYLNRDSE---GSDGGELVLGGSDPDHYVPPLTFIPVTIPAYWQVHMQSVKVGTGLN--LCAQGCGAILDTGTSLITGPSEEIRALNKAVGGFPLLTGQYLIQCSKIPELPTVSFSLGGVWFNLTGQDYVIKVQQGQSNPEPRDSQCPGVVTLQILQSDVGLCLLGFQA-LDIPKPEGPLWILGDVFLGSYVAVFDRGDKNIGPRVGLARARSRATGRAERKATQAQFLRRRPG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O96009-1", "uniprot_id": "NAPSA_HUMAN", "id": "O96009-1", "name": "Napsin-A", "aln": "-----MSPPPLLQPLLLLLPLLNVEPSGATLIRIPLH---RVQPGRRILNLLRG------WREPA--------------------ELPKLGAPSPGDK-PIFVPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLT-----------IGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPE---EPDGGELVLGGSDPAHYIPPLTFVPVTVPAYWQIHMERVKVGPGLT--LCAKGCAAILDTGTSLITGPTEEIRALHAAIGGIPLLAGEYIILCSEIPKLPAVSFLLGGVWFNLTAHDYVIQ----------------------TTRNGVRLCLSGFQA-LDVPPPAGPFWILGDVFLGTYVAVFDRGDMKSSARVGLARARTRGADLGWGETAQAQFPG----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00796-1", "uniprot_id": "RENI2_MOUSE", "id": "P00796-1", "name": "Renin-2", "aln": "MD-RRRMPLW-ALLLLWSPCTFSLPTG-TTFERIPLK---KMPSVREILEERGVD---MTRLSAE--------------------WDVFTKRSSLTDL-ISPVVLTNYLNSQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGDDFTIHYGSGRVKGFLSQDSVT-----------VGGITVT-QTFGEVTELPLIPFMLAQFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEKVFSVYYNRGP----HLLGGEVVLGGSDPEHYQGDFHYVSLSKTDSWQITMKGVSVGSSTL--LCEEGCEVVVDTGSSFISAPTSSLKLIMQALGAKEKRLHEYVVSCSQVPTLPDISFNLGGRAYTLSSTDYVLQ----------------------YPNRRDKLCTVALHA-MDIPPPTGPVWVLGATFIRKFYTEFDRHNN----RIGFALAR----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06281-1", "uniprot_id": "RENI1_MOUSE", "id": "P06281-1", "name": "Renin-1", "aln": "MD-RRRMPLW-ALLLLWSPCTFSLPTRTATFERIPLK---KMPSVREILEERGVD---MTRLSAE--------------------WGVFTKRPSLTNL-TSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVT-----------VGGITVT-QTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGS----HLLGGEVVLGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTL--LCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQ----------------------YPNRRDKLCTLALHA-MDIPPPTGPVWVLGATFIRKFYTEFDRHNN----RIGFALAR----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08424-1", "uniprot_id": "RENI_RAT", "id": "P08424-1", "name": "Renin", "aln": "MG-GRRMPLW-ALLLLWTSCSFSLPTDTASFGRILLK---KMPSVREILEERGVD---MTRISAE--------------------WGEFIKKSSFTNV-TSPVVLTNYLDTQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYTACEIHNLYDSSESSSYMENGTEFTIHYGSGKVKGFLSQDVVT-----------VGGIIVT-QTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVDGVIPVFDHILSQRVLKEEVFSVYYSRES----HLLGGEVVLGGSDPQHYQGNFHYVSISKAGSWQITMKGVSVGPATL--LCEEGCMAVVDTGTSYISGPTSSLQLIMQALGVKEKRANNYVVNCSQVPTLPDISFYLGGRTYTLSNMDYVQK----------------------NPFRNDDLCILALQG-LDIPPPTGPVWVLGATFIRKFYTEFDRHNN----RIGFALAR----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00797-1", "uniprot_id": "RENI_HUMAN", "id": "P00797-1", "name": "Renin", "aln": "MDGWRRMPRWGLLLLLWGSCTFGLPTDTTTFKRIFLK---RMPSIRESLKERGVD---MARLGPE--------------------WSQPMKRLTLGNT-TSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIIT-----------VGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSEN-SQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTL--LCEDGCLALVDTGASYISGSTSSIEKLMEALGAK-KRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQ----------------------ESYSSKKLCTLAIHA-MDIPPPTGPTWALGATFIRKFYTEFDRRNN----RIGFALAR----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z9Q9-1", "uniprot_id": "A1Z9Q9_DROME", "id": "A1Z9Q9-1", "name": "Peptidase A1 domain-containing protein", "aln": "---MWLLVSLLPVLFILPVQFQHPVSCKLQLYRVPLR---RFPSARHRFEKLGIR-MDRLRLKYA--------------------EEVSHFRGEWNSA-VKSTPLSNYLDAQYFGPITIGTPPQTFKVIFDTGSSNLWVPSATCASTMVACRVHNRYFAKRSTSHQVRGDHFAIHYGSGSLSGFLSTDTVR-----------VAGLEIRDQTFAEATEMPGPIFLAAKFDGIFGLAYRSISMQRIKPPFYAMMEQGLLTKPIFSVYLSRNGE----KDGGAIFFGGSNPHYYTGNFTYVQVSHRAYWQVKMDSAVIRN-LE--LCQQGCEVIIDTGTSFLALPYDQAILINESIGGTPSSFGQFLVPCDSVPDLPKITFTLGGRRFFLESHEYVFR----------------------DIYQDRRICSSAFIA-VDLPSPSGPLWILGDVFLGKYYTEFDMERH----RIGFADARS---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9D106-1", "uniprot_id": "PEPA5_MOUSE", "id": "Q9D106-1", "name": "Pepsin A-5", "aln": "-----MK----WLWVLGLV---ALSECLV---KIPLM---KIKSMRENLRESQVLKDYLEKYPRS--------------------RAHVLLEQRRNPA-VTYEPMRNYLDLVYIGIISIGTPPQEFRVVLDTGSSVLWVPSIYCS--SPACAHHKAFNPLRSSTFLVSGRPVNVAYGSGEMSGFLAYDTVR-----------IGDLTVVAQAFGLSLEEPGIFMEYAVFDGILGLGYPNLGLQGITPVFDNLWLQGLIPQNLFAFYLSSKDEK-----GSMLMLGGVDPSYYHGELHWVPVSKPSYWQLAVDSISMNGEVI--ACDGGCQGIMDTGTSLLTGPRSSIVNIQNLIGAKASGDGEYFLKCDTINTLPDIVFTIGSVTYPVPASAYIR-------------------------KDRSHNCRSNFEEGMDDPSDP-EMWVLGDVFLRLYFTVFDRANN----RIGLAPAA----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JJX2-1", "uniprot_id": "Q9JJX2_RAT", "id": "Q9JJX2-1", "name": "", "aln": "-----MK----WLWVLGLV---ALSECLV---KIPLM---KIKSMRENLRESHMLKDYLEKYPRS--------------------RAHVLLEQRRNPS-VTYEPMRNYLDLVYIGTISIGTPPQEFKVVLDTGSSDLWVPSIYCS--SPACAHHKVFNPLQSSTFLVSGRPVNVAYGSGEMSGFLAYDTVK-----------IGDLTVVAQAFGLSLEEPGRFMEHAVFDGILGLGYPNLGLQGVTPVFDNLWIQGLIPQNLFAFYLSSKDEK-----GSVLMLGGVDPSYYHGELHWVPVSKPSYWQLAVDSISMNGEII--ACDGGCQGIMDTGTSLVTGPRSSILNIQNLIGAKASGDGEYFLKCDTINTLPDIVFTIDSVTYPVPASAYIR-------------------------KDHSHNCRSNFEESTDDPSDP-ELWVLGDVFLRLYFTVFDRANN----RIGLASAA----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0DJD8-1", "uniprot_id": "PEPA3_HUMAN", "id": "P0DJD8-1", "name": "Pepsin A-3", "aln": "-----MK----WLLLLGLV---ALSECIMY--KVPLI---RKKSLRRTLSERGLLKDFLKKHNLN--------------------PARKYFPQWKAPTLVDEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCS--SLACTNHNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQ-----------VGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQS-----GSVVIFGGIDSSYYTGSLNWVPVTVEGYWQITVDSITMNGEAI--ACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYIL-------------------------QSEGS-CISGFQG-MNLPTESGELWILGDVFIRQYFTVFDRANN----QVGLAPVA----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DJD7-1", "uniprot_id": "PEPA4_HUMAN", "id": "P0DJD7-1", "name": "Pepsin A-4", "aln": "-----MK----WLLLLGLV---ALSECIMY--KVPLI---RKKSLRRTLSERGLLKDFLKKHNLN--------------------PARKYFPQWEAPTLVDEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCS--SLACTNHNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQ-----------VGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQS-----GSVVIFGGIDSSYYTGSLNWVPVTVEGYWQITVDSITMNGEAI--ACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYIL-------------------------QSEGS-CISGFQG-MNLPTESGELWILGDVFIRQYFTVFDRANN----QVGLAPVA----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DJD9-1", "uniprot_id": "PEPA5_HUMAN", "id": "P0DJD9-1", "name": "Pepsin A-5", "aln": "-----MK----WLLLLGLV---ALSECIMY--KVPLI---RKKSLRRTLSERGLLKDFLKKHNLN--------------------PARKYFPQWEAPTLVDEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCS--SLACTNHNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQ-----------VGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDKS-----GSVVIFGGIDSSYYTGSLNWVPVTVEGYWQITVDSITMNGETI--ACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYIL-------------------------QSEGS-CISGFQG-MNVPTESGELWILGDVFIRQYFTVFDRANN----QVGLAPVA----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3V8C5-1", "uniprot_id": "G3V8C5_RAT", "id": "G3V8C5-1", "name": "", "aln": "-----MRC---FVLLLAVL---AIAQSHVVT-RIPLH---KGKSLRNTLKEQGLLEDFLRRH------------------------QYEFSEKNSNIGVVASEPLTNYLDSEYFGLIYVGTPPQEFKVVFDTGSSELWVPSVYCS--SKVCRNHNRFDPSKSFTFQNLSKPLFVQYGTGSVEGFLAYDTVT-----------VSDIVVPHQTVGLSTEEPGDIFTYSPFDGILGLAYPTFASKYSVPIFDNMMNRHLVAQDLFSVYMSRNDQ------GSMLTLGAIDQSYFIGSLHWVPVTVQGYWQFTVDRITINDEVV--ACQGGCPAVLDTGTALLTGPGRDILNIQHAIGAVQGQHDQFDIDCWRLNFMPTVVFEINGREFPLPPSAYTN-------------------------QFQGS-CSSGFRH-------GSQMWILGDVFIREFYSVFDRANN----RVGLAKAI----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70269-1", "uniprot_id": "CATE_MOUSE", "id": "P70269-1", "name": "Cathepsin E", "aln": "-----MKPLLVLLLLLLL----DLAQAQGALHRVPLR---RHQSLRKKLRAQGQLSEFWRSHN----------------------LDMTRLSESCNVYSSVNEPLINYLDMEYFGTISIGTPPQNFTVIFDTGSSNLWVPSVYCT--SPACKAHPVFHPSQSDTYTEVGNHFSIQYGTGSLTGIIGADQVS-----------VEGLTVDGQQFGESVKEPGQTFVNAEFDGILGLGYPSLAAGGVTPVFDNMMAQNLVALPMFSVYLSSDPQGG---SGSELTFGGYDPSHFSGSLNWIPVTKQAYWQIALDGIQVGDTVM--FCSEGCQAIVDTGTSLITGPPDKIKQLQEAIGATP-IDGEYAVDCATLDTMPNVTFLINEVSYTLNPTDYILPD----------------------LVEGMQFCGSGFQG-LDIPPPAGPLWILGDVFIRQFYSVFDRGNN----QVGLAPAVP---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16228-1", "uniprot_id": "CATE_RAT", "id": "P16228-1", "name": "Cathepsin E", "aln": "-----MKPLFVLLLLLLLL---DLAQAQGVLHRVPLR---RHQSLRKKLRAQGQLSDFWRSHN----------------------LDMIEFSESCNVDKGINEPLINYLDMEYFGTVSIGSPSQNFTVIFDTGSSNLWVPSVYCT--SPACKAHPVFHPSQSSTYMEVGNHFSIQYGTGSLTGIIGADQVS-----------VEGLTVEGQQFGESVKEPGQTFVNAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVALPMFSVYLSSDPQGG---SGSELTFGGYDPSHFSGSLNWIPVTKQGYWQIALDGIQVGDTVM--FCSEGCQAIVDTGTSLITGPPKKIKQLQEAIGATP-MDGEYAVDCATLNMMPNVTFLINGVSYTLSPTAYILPD----------------------LVDGMQFCGSGFQG-LDIQPPAGPLWILGDVFIRKFYSVFDRGNN----QVGLAPAVP---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14091-1", "uniprot_id": "CATE_HUMAN", "id": "P14091-1", "name": "Cathepsin E", "aln": "-----MK--TLLLLLLVLL---ELGEAQGSLHRVPLR---RHPSLKKKLRARSQLSEFWKSHN----------------------LDMIQFTESCSMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCT--SPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVS-----------VEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGG---AGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVM--FCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAP-VDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLD----------------------FVDGMQFCSSGFQG-LDIHPPAGPLWILGDVFIRQFYSVFDRGNN----RVGLAPAVP---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D7R7-1", "uniprot_id": "PEPC_MOUSE", "id": "Q9D7R7-1", "name": "Gastricsin", "aln": "-----MK-----WMVVALL---CLPLLEAALIRVPLK---KMKSIRETMKEQGVLKDFLKNHKYD--------------------PGQKYHFGKFGDYSVLYEPMA-YMDASYYGEISIGTPPQNFLVLFDTGSSNLWVSSVYCQ--SEACTTHTRYNPSKSSTYYTQGQTFSLQYGTGSLTGFFGYDTLR-----------VQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPGLSSGGATTALQGMLGEGALSQPLFGVYLGSQQGS----NGGQIVFGGVDENLYTGELTWIPVTQELYWQITIDDFLIGNQASGWCSSSGCQGIVDTGTSLLVMPAQYLNELLQTIGAQEGEYGQYFVSCDSVSSLPTLTFVLNGVQFPLSPSSYIIQ--------------------------EEGSCMVGLESLSLNAESGQPLWILGDVFLRSYYAVFDMGNN----RVGLAPSV----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04073-1", "uniprot_id": "PEPC_RAT", "id": "P04073-1", "name": "Gastricsin", "aln": "-----MK-----WMVVALL---CLPLLEASLLRVPLR---KMKSIRETMKEQGVLKDFLKTHKYD--------------------PGQKYHFGNFGDYSVLYEPMA-YMDASYFGEISIGTPPQNFLVLFDTGSSNLWVSSVYCQ--SEACTTHARFNPSKSSTYYTEGQTFSLQYGTGSLTGFFGYDTLT-----------VQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPGLSSGGATTALQGMLGEGALSQPLFGVYLGSQQGS----NGGQIVFGGVDKNLYTGEITWVPVTQELYWQITIDDFLIGDQASGWCSSQGCQGIVDTGTSLLVMPAQYLSELLQTIGAQEGEYGEYFVSCDSVSSLPTLSFVLNGVQFPLSPSSYIIQ--------------------------EDNFCMVGLESISLTSESGQPLWILGDVFLRSYYAIFDMGNN----KVGLATSV----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VLK3-1", "uniprot_id": "Q9VLK3_DROME", "id": "Q9VLK3-1", "name": "", "aln": "-----MFKTIAVVVLLAA-------LASAELHRVPIL---KEQNFVKTRQNVLAEKSYLRTKYQ-----------------------LPSLRSVDE------EQLSNSMNMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTCKS--DACLTHNQYDSSASSTYVANGESFSIQYGTGSLTGYLSTDTVD-----------VNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYESLAVDGVAPPFYNMVSQGLVDNSVFSFYLARDGTS---TMGGELIFGGSDASLYSGALTYVPISEQGYWQFTMAGSSIDGYSL----CDDCQAIADTGTSLIVAPYNAYITLSEILNVGE--DG--YLDCSSVSSLPDVTFNIGGTNFVLKPSAYIIQS----------------------DGN----CMSAFEYMG------TDFWILGDVFIGQYYTEFDLGNN----RIGFAPVA----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKP6-1", "uniprot_id": "Q9VKP6_DROME", "id": "Q9VKP6-1", "name": "Peptidase A1 domain-containing protein", "aln": "-----MRQLLVLLVLVGIG------HSAAKLNRVQLQ---VNKNFTKTHGSVKAEKTVLASKYS-----------------------FLAETSFSVSSSGATENLHNSMNNEYYGVIAIGTPEQRFNILFDTGSANLWVPSASCPASNTACQRHNKYDSSASSTYVANGEEFAIEYGTGSLSGFLSNDIVT-----------IAGISIQNQTFGEALSEPGTTFVDAPFAGILGLAFSAIAVDGVTPPFDNMISQGLLDEPVISFYLKRQGTA---VRGGELILGGIDSSLYRGSLTYVPVSVPAYWQFKVNTIKTNGTLL----CNGCQAIADTGTSLIAVPLAAYRKINRQLGATDN-DGEAFVRCGRVSSLPKVNLNIGGTVFTLAPRDYIVKV----------------------TQNGQTYCMSAFTYMEG-----LSFWILGDVFIGKFYTVFDKGNE----RIGFARVADY--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQ12-1", "uniprot_id": "Q9VQ12_DROME", "id": "Q9VQ12-1", "name": "Peptidase A1 domain-containing protein", "aln": "-----MLKWLVLLTILAL--------VSAEIHRIKIH---KNQDHKNTRQHRKQAIQALKLKYHQQDVVIIYDDGVPIYMQPDYGYDYPSQTSVDYTS----EELGNSMNMYYYGLIGIGTPEQYFKVVFDTGSANLWVPSAQCLATDVACQQHNQYNSSASSTFVSSGQNFSIQYGTGSVSGYLAIDTVT-----------INGLAIANQTFGEAVSQPGASFTDVAFDGILGMGYQQIAEDNVVPPFYNLYEEGLIDEPVFGFYLARNGSA---VDGGQLTLGGTDQNLIAGEMTYTPVTQQGYWQFAVNNITWNGTVI----SSGCQAIADTGTSLIAAPSAAYIQLNNLIGGVPI-QGDYYVPCSTVSSLPVLTINIGGTNFYLPPSVYIQTY----------------------TEGNYTTCMSTFTDIG------TGFWILGDVFLGQYYSEFDFGQN----RVGFATLA----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07267-1", "uniprot_id": "CARP_YEAST", "id": "P07267-1", "name": "Saccharopepsin", "aln": "--MFSLKALLPLALLLVSANQVAAKVHKAKIYKHELSDEMKEVTFEQHLAHLGQKYLTQFEKANP--------------------EVVFSREHPFFTEGGHDVPLTNYLNAQYYTDITLGTPPQNFKVILDTGSSNLWVPSNECG--SLACFLHSKYDHEASSSYKANGTEFAIQYGTGSLEGYISQDTLS-----------IGDLTIPKQDFAEATSEPGLTFAFGKFDGILGLGYDTISVDKVVPPFYNAIQQDLLDEKRFAFYLGDTSKDT--ENGGEATFGGIDESKFKGDITWLPVRRKAYWEVKFEGIGLGDEYA---ELESHGAAIDTGTSLITLPSGLAEMINAEIGAKKGWTGQYTLDCNTRDNLPDLIFNFNGYNFTIGPYDYTLEV--------------------------SGSCISAITP-MDFPEPVGPLAIVGDAFLRKYYSIYDLGNN----AVGLAKAI----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . : : * : :*:* * * : :*:**: :**.* * * * : * :. . . : *.:* : * :. * : .: .. * : * *:.*:.: . . : . : :..* *. :*. : : : : *:. . . ***:: : . : :. : * :* : : :. : : * * : :* .*: : : :* :*:* ", "identical_positions": 39, "similar_positions": 80, "identity": "7.83%" }, { "cls_id": "homologset.agr.SGD:S000006076", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZV60-1", "uniprot_id": "D3ZV60_RAT", "id": "D3ZV60-1", "name": "Centromere-associated protein E", "aln": "MTLRSPIRCDAEDILNLKAGRPGSSVGAVDPLHFPSWAAADRMAEEAAVAVCVRVRPLNSREEELGEASHIYWKTDKNAIYQSDGGKSFQFDRVFHSNETTKNVYEEIAVPIISSAIQGYNGTIFAYGQTASGKTHTMMGSEDCLGVIPRAIHDIFQRIKKFPEREFLLRVSYMEIYNETITDLLCNTQKVKPLIIREDINRNVYVADLTEEVVYTAEMALKWLATGEKNRHYGITKMNQRSSRSHTIFRMILESREKAESSNCDGSIKVSHLNLVDLAGSERAAQTGAEGMRLKEGCYINRNLLILGQVIKKLSDGQVGGFINYRDSKLTRILQNSLGGNAKTRIICTITPASLDETLTTLQFASTAKYMKNTPYVNEVSNDEALLKRYRREIVDLKKQLEEVNTKTRAQEIEKDQLAQLLDEKDLLQKVQDEKIQNLKRMLVTSSSIALQQELEIKKKRRVTWCFG---KMKDSNYVKEFKIPTNITTRTRKTSVTPLRENSLMKLGESALSWESEVFDNTLEPLAEAEWSSATALLSEENLESELTSLNTQYNNLVLDYEQLRRENEDLKLKLKEKNELEEFEFLEQREEKDQELQLMHEVSNLKNLIKHAEEYNQDLENELSSKVELLKEKEDQIKELQRYIDA-QKSETTKTDLSYSSEATEDLKQAMRTLSDLDTVALDAKRESAFLRSENLELKERINELSDSCKQMENGIQMYQRQLEAKKQVQADLEKELQLAFQEISKLSALVDG---KGLLSNLELEKRITDLQKELNKEVEEKETLQKEVHLLSELKSLPSEVETLRRELHEKSEELCVITTEREKLFSEMAHKDSRIQGLLEEIGNTKDDLAASQLSQRSSDEECQALKSLHVELKHRQEEVLEESERVKQEL---------------------SQKTQELAQKTAEGQEMLNQMEELREKLERRDSSLQSAEKEKNLLTEKLQQTLEEVRALTQEKNDLKQLQESLQTERDQLRSDIQDTVNMNIDTQEQLLN-ALESLKQHQETINMLKMKATEEMSDHLPIKG-REGSSDEVEQKLDGID-EENLLAESAHTVVGSGEDHGETEEQRKIDSLLQENSRLQQTLESIIAEKEQLKMDLKENIEMSVENQEELRILRDELKRQQEIAAQEKDHVTEKSEELSRAHERLAEIEEKLKEKNQKLQETQ---QQLVSIQEAMSEMQAKVTDLENLQNEFRNQALALERVETERLELAQKLHENYEKMESITKERNDLKELQESFEIEKKQLKEYAREMESAG---LQTKEQLNIAHANLKEYQEIIKELRGSISEKEAQASSTQDTGKTNPASQGETPVPRE-QELLPDAEEARASAEKGSELEPVEEHSRTAHSLTTEGIEMEILALTKKLEESQKEISCLTKERS---------------------------------------------------------------------------------------------DLRRTQEALQVECAQLKDDARRTLANHLETEEELSLARCCLKEQENKIDSLIVSLSQKEAELSSVRVQLEVTTGELERKVQELCEKQEQLNIKETSEVQGKMSELDHIRALLLTKDSALQSVESDRLRLNKQLEESQEEIKILIKEREELRRAQEALHVEREQQQESIKEISTRLQELQDKEYEYLVMKSLNETQGNKCED--LNQQLEAQKSSLEKVEMQNVNLTQRLNETLEEMKSVAKERDELRSVEERLTADRDQLKKSLEETITK----------------------------------------------------------------------------------------------------------NQELQEKGHQLSQVKADLRET---MDQMEQLKEQLEAQNSTLESIEIEKLKLTQQLNENLKEMTLVAKENDDLKIMDEALREERDQLRESLRQTEASDLEKQEKLRIAHLDLKEHQETIERLMGSVAKRTEEVSDMNMELERANTRLQEKVQELKASELQLLKSKVEA----------GETKKQLKEQGLALSKIEMENLNLAQQIHQNLEEMKSISKERDDLKRMEEILRMEKDQLKDSLREAKFKAHQNYEETVQYGKGLLCGGEQHCTGRLREKCLRIEKLLKRYSEMANDYECLNRFSLDLEKETKTQKELSVTIKTKLSLPYTQTKEIEKLLTANQRCSMEFHRILKKLKYVLSYITRIKEEQHEFINKFEMAFIQEVEKQNELQIKIQSLSQTSNIPSRDS-QSKLSQEMDLHIEEILKDFSENDFLTIKTEVKQVLSNRKEITEFLEKWLNTHFDTENLKSSIQKENKSIGLVNNFYHSKITAMVNESTEFEERCAARAKDLERHLKALTETTEQLSKVYQSLTVSWSIVR------PSTQDSKDPRVALEAEQLTSK--------------------------------------------------------------DKNALGAMPYKEEIEDLKMQLVKIDLEKKAKAKEFEKEMLAIKATVEHQEEVIRLLRENLRRNQQAQDTSMLSEQ-DSHPLRKPLTCGGGSGIVQSTKALILKSEYKKMESEISKLKQQNEQLRKQKNQLLCDNSQLSKEVKSWEERTLRRDSYREASHENPPKSPAVTGMESKRRQNTASQCKERNFQDPVPKDSPKSSFFDSRSKSLPAPPPIRYFDNSSLGLCPEE-PAEIENVDPKANLCQASSGKDVSECKMQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6RT24-1", "uniprot_id": "CENPE_MOUSE", "id": "Q6RT24-1", "name": "Centromere-associated protein E", "aln": "------------------------------------------MAEEASVAVCVRVRPLNSREEELGEATHIYWKTDKNAIYQSDGGKSFQFDRVFDSNETTKNVYEEIAVPIISSAIQGYNGTIFAYGQTASGKTHTMMGSEDCLGVIPRAIHDIFQRIKKFPEREFLLRVSYMEIYNETITDLLCNAQKMKPLIIREDTNRTVYVSDLTEEVVYTAEMALKWLATGEKNRHYGITKMNQRSSRSHTIFRMILESREKAEPSNCDGSVKVSHLNLVDLAGSERAAQTGAEGVRLKEGCFINRNLFILGQVIKKLSDGQVGGFINYRDSKLTRILQNSLGGNAKTRIICTITPASLDETLTTLQFASTAKYMKNTPYVNEVSNDEALLKRYRREIADLRKQLEEVNTKTRAQEMEKDQLAQLLDEKDLLQKVQDEKINNLKRMLVTSSSIALQQELEIKRKRRVTWCYG---KMKDSNYEKEFKVPTSITTRKRKTSVTSLRENSLMKFGESAASSEFEMLNNTLESLAEVEWSSATTLLSEENVESELNSLNAQYNDLVLDYEQLRRENEDLKLKLKEKNELEEFELLEQKEERDQEMQLMHEVSNLKNLIKHAEEYNQDLENDLSSKVKLLKEKEEQIKNLQEYIDA-QKSEKMKIDLSYTSDATEDLKQAMRTLSDLDTVALDAKKESAFLRSENLELKEKINELSDSRKQMESDIQMYQRQLEAKKKMQTDLDKELQLAFQEISKLSALVDG---KGLLSNLELEKRITDLQKELNKEAEEKQTLQEEVNLLSELKSLPSEVETLRRELYEKSEELHIITTEREKLFSEMAHKDSRIQGLLEEIGNTRDDLATSQLSRRGSDGEWQALESLHAELEHRHAGVLEERERLKQEIGALSKEAESLAFSLDSVKAELSHKTQELEQKTVEGQERLNKMEALREELESRDSSLQSVEKEKVLLTEKLQQALKEVKALTQEKKNLKQLQESLQTERDQLRSDIQDTVNMNIDTQEQLLN-ALESLKQHQETINMLKMKAAEELSDNLHVKD-RGGARDEAQQKMDGID-EQN---ESAHTLLGGGKDNEVTEEQRKIDSLMQENSGLQQTLESVRAEKEQLKMDLKENIEMSIENQEELRILRDELKRQQEVAAQEKDHATEKTQELSRTQERLAKTEEKLEEKNQKLQETQ---QQLLSTQEAMSKLQAKVIDMESLQNEFRNQGLALERVETEKLELAQRLHESYEEVKSITKERNDLKELQESFEIEKKQLKEYAREIEAEG---LQAKEELNIAHANLKEYQEIITELRGSISENEAQGASTQDTAKSAPELQGEVPELLE-QELLPVVKEARHSAEKVNGLEPVGAHSRTVHSMTMEGIEIGNLRLTKKLEESQMEISCLTRERE---------------------------------------------------------------------------------------------DLRRTQETLQVECTQLKEDARRTLANHLETEEELNLARCCLKEQENKIDTLITSLSQRETELSSVRGQLALTTAELERKVQELCEKQEELTRKETSEAQGKMSELEQLRELLLAQASALQNAESDRLRLNTQLEESQEEMKTLREEREELRRMQEALHVESEQQKESMKEISSKLQELQNKEYECLAMKTINETQGSRCEMDHLNQQLEAQKSTLEKVEMENVNLTQRLHETLEEMRSVAKERDELWSMEERLTVERDQLKKSLEETVTKGMEKEEELRVAHVHLEEHQETINKLRKMVSDYTDEISHTQGDLKHT-----------------------------------------------------NAVVEAQNQDLREKEHQLSQVKADLRET---VDQMEQLKKKLEAQSSTLESREIEKLELTQQLNENLKKITLVTKENDSLKIMDEALREERDQLRKSLQQTEARDLENQEKLRIAHMNLKEHQETIDRLMETMSEKTEEISNMKMELENVNMKLQEKVQELKTSERQRVKLKADA----------SEAKKELKEQGLTLSKIEMENLNLAQKIHENLEEMKSVRKERDDLKKLEEILRMERDQLKDNLREAMLKAHQNHEETMKCGKGLLCAG-EYCTGRLREKCFRIEKLLKRYSEMANDYECLNKVSLDLERETKTQKELSVTVRTKLSLPHTQTKEMEKLLTANQRCSLEFHRALKRLKYVLSSIARIKEEQHESINKREMAFIQEVEKQNELQIQIQSLSQTYRIPARDL-QIKLSQEMDLHIEEMLKDFSENDFLTIKTEVQQVLNNRKEITEFLGKWLNTLFDTENLKSTIQKENKSIGLVNNFYHSRITAMINESTEFEERSATRSKDLDQYLKSLKETTEQLSEVYQTLTASQSVVHLHPTVQPSTRDSERPQAASGAEQLTSK--------------------------------------------------------------NKIALGAVPYKEEIEDLKMQLVKSDLEKKATAKEFDKKILSLKATVEHQEEMIRLLRENLRGHQQAQDTSMISEQ-DSQLLSKPLTCGGGSGIVQSTKALILKSEYKRMGSEISKLKQQNEQLRKQNNQLLSDNSQLSNEVKTWEERTLKRDSYRETTCENSPKSPKVTRTDSKRRQNTTSQCRAQNLQDPVPKDSPKSWFFDNRSKSLPAPHPIRYFDNSSLGLCPE--PDDVENVEPKTDLCQASLEKDVSQCKTQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02224-1", "uniprot_id": "CENPE_HUMAN", "id": "Q02224-1", "name": "Centromere-associated protein E", "aln": "------------------------------------------MAEEGAVAVCVRVRPLNSREESLGETAQVYWKTDNNVIYQVDGSKSFNFDRVFHGNETTKNVYEEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMGSEDHLGVIPRAIHDIFQKIKKFPDREFLLRVSYMEIYNETITDLLCGTQKMKPLIIREDVNRNVYVADLTEEVVYTSEMALKWITKGEKSRHYGETKMNQRSSRSHTIFRMILESREKGEPSNCEGSVKVSHLNLVDLAGSERAAQTGAAGVRLKEGCNINRSLFILGQVIKKLSDGQVGGFINYRDSKLTRILQNSLGGNAKTRIICTITPVSFDETLTALQFASTAKYMKNTPYVNEVSTDEALLKRYRKEIMDLKKQLEEVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEKIENLTRMLVTSSSLTLQQELKAKRKRRVTWCLGKINKMKNSNYADQFNIPTNITTKTHKLSINLLR-----EIDESVCS-ESDVFSNTLDTLSEIEWNPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDS-QKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRN-ALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQ---QQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATG---LQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPE--KRLLSDGQQHLTESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSMRVKANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQHESINKFEMDFIDEVEKQKELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQVN---PTTQDNKNPHVTSRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALGAKPYKEEIEDLKMKLVKIDLEKMKNAKEFEKEISATKATVEYQKEVIRLLRENLRRSQQAQDTSVISEHTDPQPSNKPLTCGGGSGIVQNTKALILKSEHIRLEKEISKLKQQNEQLIKQKNELLSNNQHLSNEVKTWKERTLKREAHKQVTCENSPKSPKVTGTASKKKQITPSQCKERNLQDPVPKESPKSCFFDSRSKSLPSPHPVRYFDNSSLGLCPEVQNAGAESVDSQPGPWHASSGKDVPECKTQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKI0-1", "uniprot_id": "Q9VKI0_DROME", "id": "Q9VKI0-1", "name": "", "aln": "----------------------------------------MSAKNASSIQVCIKVRPCEP-----GLTSLWQVKERRSIHLADSHAEPYVFDYVFDEGASNQEVFDRMAKHIVHACMQGFNGTIFAYGQTSSGKTYTMMGDEQNPGVMVLAAKEIFQQISSETERDFLLRVGYIEIYNEKIYDLLN--KKNQDLKIHESGN-GIVNVNCEECIITSEVDLLRLLCLGNKERTVGETNMNERSSRSHAIFKIIIESRKSDHSD--DDAVIQSVLNLVDLAGSERADQTGARGARLKEGGHINKSLLFLSNVIKSLSENADNRFTNYRDSKLTRILQASLGGNAFTSIICTIKPSIMEESQSTLSFATRAKKIRIKPQVNEMVSDATMMKRLEREIKVLKDKLAEEERKNENQQK--------------VEHLERQIKHDMHKIICGHS-----LSDKGQQKRRRTWCPTASGS---HLELAETGTTEDRIDQFPKVSHLPKP----VFFHTSNAGKRWDNIPKTINILGSLDIGTESNSISEEFLPAECIDFGSPRPDVLKPMLTIRQLP----------------DLPLTPKGPLTTDKIKKEIQDLQMFTSLEKHFEVECEEVQGLKEKLAEVTAQRDNLEQESLAEKERYDALEKEVTSLRADNEAANSKISELEEKLSTLKQTMRIMEVENQVAVGLEFEFEAHKKSSKLRVDDLLSALLEKESTIESLQKSLDNLTRDVLRNSKEGHMLSIAPEQEDIAGDSICNKCEELEKLIADLESK---------------KNSCECDQLRLEIVSVRDKLESVESAFNLASSEIIQKATDCERLSKELSTSQNAFGQLQERYDALDQQWQAQQAGITTLHEKHEHVQEKYQKLQEEYEQLESRAR-------------SASSAEFQRLQNDNTKFQADIASLNERLEEAQNMLTEVQNSESTVEKLRIQNHELTAKIKELETNFEEMQREYDCLSNQLMESVQENDALREEIKQRPTSHVEESMRSSGISSDFD--EQKQDINLLHQFVQLSESVQQIELQHHSGIS------------RLFRANQMKLDQSEPGLKLCLESAEYIEEDNRQSDATEPICLKGFLKRHRFQIKRLSQEHVDMGEEKRLLDIISQLEQEIEEKSALMEATEATINEMREQMTNLESALLEKSVIINKVEDYQRQIESLEKQNAEMTMVYEELQDRVTRESSMSESLLRVPPDEDTLPGCPTSPSRREQEVATLKTSITELQSQVSDLKAELENHLRQIQLKDGNIARLQTDFEEMSERCLSMEVRLAELDEDTKQKQELLDRQAQKLSDDLCLID-QLQKKNAQLVEQYHKATESLSLADAKPDQ--ILLSSQYDSQIEKLNQLLNAAKDELHDVRRIKDD-------------------------------------------------------------------------------------------EISALRMEFLLQIETNEKENQAKFYAELQETKDRYESNVAELKEKLLQVEETLSSVTVR------CQAELEALKSAHKENISQAVEERNNLIVQHQAEMETIRETLKNKLAEASTQQSKME--DAFRAEINEVRATLMEQLNQTKEDRDKGASKLEEVKKTLEQMINGGRVMSDTIAELEKTK--------------------------AEQDLAVNKLTKDNIELEKQCSKTQEQLQMESLTRDQISFEIEAHIKKLELIVASSKKRIIE------------------------------------------------------------------------------------------------------------LEEKCDQQVLELDKCRLEKLSLESEIQKANSEHSCTMEKLQELQAEMKVLSNRNEK----------EKCDFETKLETFTFKITDLEEVLKEAQHK-VILYDDLVSQHERLKICLAEANELSSNLQKKVMSLHTELIDSQKGISSRDVEINELREELKAAMDAKATAS---------AEQMTLVTQLKDVEERMANQAEKFTREAANLKGSINELLLKLNSMQETKDMLESGNEELKEQLRNSQNLRN-------------MLDEESKMCISLKEKLVKLEDAKTSLEQQLRDNKSE------IYQRHTELTKEVELGRNRIGELTKKCEELCSDLENSDQIRLDLQETKEQLKKTLENNLGWQQKVDEVTRECEKLRFDMQSKEVQNESKVQELISECEELRSTL------------------KSKEASFQSEKESMDRTISSLLEDKRNLEEKLCSANDIVAKLETEIAALRPRKSLDRNPVPRKSITFESEIRKNRRISVHDERRQSYWNDVREFGI-----------------------MTDPVDNNCNCAELNSKLQDC-------------------------------------------------------------------QRELFIRESQVTALKMELDHHPLKDENAQLTKRVIEEQDKAKVEQKRLKMKLQDLNARINDLTTASAKEP--------------ESNQMAQAAKPATVAAQTQTESDLETILEKTNVKYQEAVRMLRYRYHLIQELKEKLRQNENSDTSNITSLSAGQTSALKAQCESQKKEILAIKYKYEAAKRILAIRNDDLDALREKLAKYETTTSDK------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKH9-1", "uniprot_id": "Q9VKH9_DROME", "id": "Q9VKH9-1", "name": "", "aln": "----------------------------------------MSTKNASSIQVCIKVRPCEP-----GLTSLWQVKEGRSIQLADSHAEPYVFDYVFDEGASNQEVFDRMAKHIVHACMQGSNGTIFAYGQTSSGKTYTMMGDEQNPGVMVLAAKEIFQQISSETERDFLLRVGYIEIYNEKIYDLLN--KKNQDLKIHESGN-GIVNVNCKESIVTSEDDLLRQLYMGNKERVVGETNMNERSSRSHAIFRIIIESRKSDHSD--NDTVKQSVLSLVDLAGSEQVDPADH-----------ASSLMIFRNLVKSLSESVDSKPNSFRDSKLPRIMLPSLGGNVLTSIICTITPSFVEESSSTISFGTCAKKIRCKPQVCKIDSETTMMRQLDRGISMLKDKLAKKKIKNESQLV--------------LQELEGRIKRDMLKIVSSAS-----LDDYRLQKRRRTWTLTASGSEGDAPVLALPEPEESRLPRPSKLTNLPKP----LFQRRGIAPKAKG----------------ICKTLKEKRLQTDNMDTMPGRAKQLG-RETASRIP----------------SVMMSKK-------------------------------------------------YQESVPN---CDAPQTEISALTASNQVAKETIEKYEEQVKRLKETIERLEMENGKAVNLGEQFETHKAKSKQMEEELLSSISEKDSTIVSLQQSLEELSRDVLRNSKEDQMRSMCPELESSC-ERICNKCLELERLLPLASASG------------LDSVACQFDQLRSEIAATRMKLESMLSTFSHASCEVSQKTTDCKRLSEQISTAHDDFGQLQEKYNNLKHKWSSQKLAIDTMQVDYNTIQQKYLQLQDEYRHLELRS-----------------DEQCQQLQDENSKLQAEIGTLKERVEEIHSELLEVPNPDTHPEDMELQNQELKKRLSKLQWEFDEIQLNYECLSNELMSTIQECDALREEHKQRTTNSDLESMKSSGVGTECSDPENELDTDLLQQFTKLSKSIQQIELTDYSGGR------------RLFIYNHAEQDQSVPSLKLCLEPAKYLEGDGKQHDASDSVFLKGFLKCQRFQIVKINQEQNLVKEEDRMRDIIFQLKQEVDGKKNLIEEEKEVINNLRAQITSLN------------------QIETIKNQNAKTKILCEELQTKDT---------------------VQTANKQESQEVLTLKTSLAHLKSKVCELQKKLE-----KQSEDEKISELQSDIGEISECCLSMELKLADIVN--------------WQAEELRPLD-QLQESGVELQHHSTTAEESLNVEKPIQEQTERTLTTEYERRIEQLEESLQRAQEELSILEKRKTD-------------------------------------------------------------------------------------------ENKSLQLEYMAKIETSENENRSKFRAYCLDLKETQKR----YEEQLQQTNEKLASVTTQ------CQVHLDVIKRSLQEKITQAEKERNELAVRHKAELEKIRETLK------------------------EKESSYKEKLRQAEEERDKEISRLEVMRN--------------TIAELHKTN--------------------------SDREVELEGVKMEKCQLKKLYDKSMLELEQLQCTADQ---------KSSDLLPGSSNENIDD------------------------------------------------------------------------------------------------------------LQKKCDQYVQDLELLRGEKAELLSEIQKINGQHSNTIKKLEEIEAEMITLTTQKEL----------ERCEIAEKLETFKSKEADIKEALHCAQLR-LHAYDKLVCEYERLKGCLSDSNKLSENLQKKVERLHAEQLALQEGISGRDSEIKQLRSELKDAIDENKTVR---------EAKVGLENSLKAVQENMSAQEGQFKQKIADIKGSVDELQIKLKSLQEVRDHLESRNEELKRKLKDAQELQN-------------MVDKERKLNSSLREDFDKLEQTKLDLEEQLRAKKVE------IDRRSKEL-----------GEVTKDCENIRSDLEAQT---NDFLKERETLNLTISDLRLHNEQLLETSKNYLSDITAANNLNLEMKKNLHDLTKECKSLRSDL------------------QSKEEYFQTQKQLLDETISNLKEENRKMEEKLSSGN---KALKEDCEKLR--STLE----SKELILQQNKQELEERLTVINEK-------------------------------------------NGKNALLDAQLKS--------------------------------------------------------------------------NETAFTSLRKAWIKQSLAIEAAN--KRSLEMEQKVDKRTREYEELRSTLKTREINFRSEKER---------------------MDGTISSLLEDKRNLEEKLCTVTELL-AKLKRELPALHTQKVNGGDVSIELNSSNGSPTPAAVPATKKPLDCNSAECVPKKSSSLETAER----------KNRRMTAYDENRKQFC------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28743-1", "uniprot_id": "KIP2_YEAST", "id": "P28743-1", "name": "Kinesin-like protein KIP2", "aln": "----------------------------------------------------------------------MIQKMSPSLRRPSTRSSSGSSNIPQSPSVRSTSSFSNLTRNSIRSTSNSGSQSISASSTRSNSPLRSVSAKSDPFLHPGRIRIRRSDSINNNSRK------------NDTYTGSITVTIRPKPRSVGTSRD-----------------------HVGLKSPRYSQPRSNSHHGSNTFVRDPWFITNDKTIVHEEIGEFKFDHVFASHCTNLEVYERTSKP-------------------MIDKLLMGFNATIFAYGMTGSGKTFT--MSGNEQELGLIPLSVSYLFTNIMEQSMNGDKKFDVIISYLEIYN---------ERIYDLLESGLEE----------------------------SGSRISTPSRLYMSKS--------------------------NSNGLGVELKIRDDSQYGVKVIGLTERR------------------------------------------------------------------------------------------------------------------------------------------------------CESSEELLRWIAVGDKSRK--IGETDYNARSSRSHAIVLIRLTSTNVKNGTSRSSTLSLCDLAGSERATGQQERRKEGSFINKSLLALGTVISKLS--------------------ADKMNSVGSNIPSPSASG-----------------------------SSSSSGNATNNGTSPSNHIPYRDSKLTRLLQPALSGDSIVTTICTVDTRNDAAAETMNTLRFASRAKNVALHVS--------------------------------KKSIISNGNNDGDKDRTIELLRRQLEEQRRMISELKNRSNIGEPLTKSSNESTYKDIKATGNDGDPNLALMRAEN-------RVLKYKLENCEKLLDKDVVDLQDSEIMEIVEMLPFEVGTLLETKFQGLESQIR----------------------------QYRKYTQKLEDKIMALEKSGHTAMSLTGCDGTEVIELQKMLERKDKMIEALQSAKRLRDRALKPLINTQQSPHPVVDNDK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . ... : . . . :..:: : : :. . :* * . :.. :: ...: : *.. . : *:. . : : : : . : * *. . .. *.: . . : : :... . . . : . :. * :. ::..* . : : : : :.** : .:. . . .: * . : : *.. * : . :: * . : : : : : . : . . . : . * . . : : .: : . . . .: : : * : . . . . . : . : . . : . : *...:* : . . . : : : : : : . : :: . .::. . : :. :: . . : : : .. : . : * . : ", "identical_positions": 21, "similar_positions": 176, "identity": "0.76%" }, { "cls_id": "homologset.agr.SGD:S000006078", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P85107-1", "uniprot_id": "TGS1_RAT", "id": "P85107-1", "name": "Trimethylguanosine synthase", "aln": "---MCCEKWSHVAEMLLFIEDREEEYKILCLCSRAFVEDRKLYNLGLKGYYVKSSGNNAGDRVTEEEE---DDHSSGTTESHSA-----DEGDLDPEAKLMRSMGLPVRFGRMSTHGSFEVSMNARNKAKVRQKRRKHRKQYLDEIVREDWRNDCEEDDLVVSDDPSSVEHCENNSACEIQSKTDAEAENLPVENTLAPKLEVTENWEKYWNEYGEGLLWQSWQEKYPDQTLSSEPWNLPDTKEEWEQHYSQLYWYYLEQFQYWEAQGWTFVASQNCDKDVCTSHTQVD-QNAESSLKADGTTLSSSPNTAEDESLGSNDNDHNEIIAGINKITLSAEEVEQSQLDSSEHCD--KPLSEVTG-KECPASGGSDSCHG-TPKESDISENRSSDQPAQELQESSGTNTSKHRPHHNGTDGNESEDDPPDHKPSKMKRSHELDIDENPDSEVDDNGFHLGFKHGSGQKYGGIPNFSRRQVRYLEKNVKYKSKYLDMRKRMTVKNKHIVFSEESGKPFIR-KSKVRSKVEKFLKWVNEPVD-EEISQEPL------SHNKMQDTCTSSDSEEQDMSMEKTDGLMETRDPEP-----ENCQTISSASELEAEKSEGGSLVAAVP--ENCSTEGVANSPRAEAEVEIKKKKKKKKKNKNKKINGLPPEIASVPELAKYWAQRYRLFSRFDDG-IKLDKEGWFSVTPEKIAEHIAGRVSQSFN-CDIIVDAFCGVGGNTIQFALTGKRVIAIDIDPVKIDLARNNAEVYGVADKIEFICGDFLLLAP-----CLKADVVFLSPPWGGPDYATAETFDIRTMMSPD-GFEIFRLSQKITNNIVYFLPRNADVDQVASLA----GPGGQVEIEQNFLNNKLKTITAYFGDLIRRPALR---SAEA---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q923W1-1", "uniprot_id": "TGS1_MOUSE", "id": "Q923W1-1", "name": "Trimethylguanosine synthase", "aln": "---MCCEKWNHVAEMLLFIEDREEEYKILCLCSRAFVEDRKLYNLGLKGYYVKSSGNNAGDQGTEEEE---DGHSNGTAESHSP-----NESDLDSEAKLMRSMGLPIQFGRMSSHENFEMSMNARNKAKVKQKRRKHQKRYLDEMVRESWRNDYEEDDLVVSDDPSSVEHCENNRTCEIQSKAGSEVENLPVENTLAPKLEVPENWEKYWNEYGEGLLWQSWQEKYPDQTLSSEPWNLPDTKEEWEQHYSQLYWYYLEQFQYWEAQGWTFTASQNCDKDVYTSHTEVD-QNAESSLKADVMTFSSSPNIVEDEIPGSNDNDHNEIITAINNITVSAEKVEQSQLDSSQHCD--EPLSEITG-KECPASGGSDSCNG-TPKENDISENRSSDQPAKELQESSGTNKGKHRPHHNGADGHESDDDPPEHKPSKVKRSHELDVDENPDSEVDDNGFLLGFKHGSGQKYGGIPNFSHRQVRYLEKNVKYKSKYLDLRKQMPVKSKHILFTEDSGKPFVVCKSKVRSKVEKFLKWVNERVD-EETSQDSL------SQNKMQDTCTSSDSEEQDMSLEKADNLMETRDPEP-----EKCQIISSATELEAEKSEVGSLVATVP--ENCSTEEIPNSPHAETEVEIKKKKKK---NKNKKINDLPPEIASVPELAKYWAQRYRLFSRFDDG-IKLDKEGWFSVTPEKIAEHIAGRVSQAFR-CDVVVDAFCGVGGNTIQFALTGKRVIAIDIDPVKIDLARNNAEVYGIADKIEFICGDFLLLAP-----CLKADVVFLSPPWGGPDYATAETFDIRTMMSPD-GFEIFRLSQKITNNIVYFLPRNADIDQVASLA----GLGGQVEIEQNFLNNKLKTITAYFGDLIRRPALLKTSTSEAEV-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RS0-1", "uniprot_id": "TGS1_HUMAN", "id": "Q96RS0-1", "name": "Trimethylguanosine synthase", "aln": "---MCCEKWSRVAEMFLFIEERED-CKILCLCSRAFVEDRKLYNLGLKGYYIRDSGNNSGDQATEEEE---GGYSCGTAESHDSKGIGLDESELDSEAELMRSMGLPLQFGRITAHKDFEVSMNTRNKVKIKKK--KHQKKYLDEIVQESWRKEYEEDDILASDDPSSIEQYENTRTYELQSKKDTETENPPVENTLSPKLEITEKWEKYWNEYGGGLLWQSWQEKHPGQALSSEPWNFPDTKEEWEQHYSQLYWYYLEQFQYWEAQGWTFDASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFK-KSKILSKVEKFLTWVNKPMD-EEASQESS------SHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEP-----EKCQSVSSAGELETENYERDSLLATVPDEQDCVTQEVPDSRQAETEAEVKKKKNK---KKNKKVNGLPPEIAAVPELAKYWAQRYRLFSRFDDG-IKLDREGWFSVTPEKIAEHIAGRVSQSFK-CDVVVDAFCGVGGNTIQFALTGMRVIAIDIDPVKIALARNNAEVYGIADKIEFICGDFLLLAS-----FLKADVVFLSPPWGGPDYATAETFDIRTMMSPD-GFEIFRLSKKITNNIVYFLPRNADIDQVASLA----GPGGQVEIEQNFLNNKLKTITAYFGDLIRRPASET---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GD28-1", "uniprot_id": "A0AC58GD28_DANRE", "id": "A0AC58GD28-1", "name": "Trimethylguanosine synthase", "aln": "MMIDYGERNVVPLADIIFYQGEETEMTIHCLCSRAYVNDRELYRSDFKAISSQADSQVQGDVETNDGEQLLEDLNCSVDEDEEEEEEE-EDAAVDEETLLMASLGLPVQFASSSKQR-------RAGQVLARPK------------------------------NKRTVKCLETSSDYTDANENSEDIAEPPCEQICP---TSDEAWLRYWQQHGEGLLWQSWLEKHPENS-SSTVQDFSHSQTDWDDHFQQIYKYYWEQFQYWAAQGWTLDESYSTTAASEENQNCQG-----------------ETEALESETKDRSKADASSVTHLISSLSLLTEEVDMD--------D--GRQPLVCSCADEPCDGGNRKRPSSRAACTDASDGNMKQTSGSAPMNNGSGRPTKSRSNDEDQSDDDDDDEPPGNRRAKVKRAHELDAEEIAEVPVEEAWDALGLRRGSQPKFESVVKLKAGQGSYTGRRREDRKPPEQRRKAACKINKHIFFTDDGPQTTKPKISKALQKVQSFLQQVQTDADSEDVATTSMPEALIGPFDKAELASLPTRKEDEEEASNDTDEEDCETTPQPSRICEEQQHIIPDLEEIHEDEADPRGELQPLDVPDFLLPDAHEDTKKESVQAFKKNKRKK---RKRRKDVEMPPEIAAEPELAKYWAQRYRLFSRFDEG-IKLDHEGWFSVTPEKIAEHIALRVQDCFN-TELIIDAFCGVGGNAIQFALTGKRVIGIDIDPVRLALAQHNAAVYGVEQRIDFLQGDFLQLAP-----HLRGDMVFLSPPWGGPEYLTADVFNIQTMMTPD-GFEIFRLSKMISDNIVYFLPRNADMEQIASLA----GPGGKVEVEQNFLNNKLKTITAYFGNLIK---------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEA4-1", "uniprot_id": "Q9VEA4_DROME", "id": "Q9VEA4-1", "name": "Trimethylguanosine synthase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------MNTHHLTTSRTNPQFYIFSQLFGNDFDWNNCNWGGIQNVTWKEFWQREGHELLEQKWHKRFPEYKDLIEVVSS-EEQGLWQELWEKHASDYSEKFWYIFSCAFENYQHDLAKSFGLDVAENSE----------------------------------------------------------------------------------------------DVEEDLQNLSLTNKPIKSKQQRVTEKEEDESYLTANDDPED----------------------CDEEQQLRLLGLPTSFASKADIINYRKERK------------------------------------------------------------------------------TQYELSSSDSEDDHDLLTMENNEN----------------------------------------------------EALHGVQSGSVKKKKRRQRQIKKLKARMPECMQEDNNKMVKYWVKRFSLFSRFDQG-IRLDRESWFSVTPEKIAKQTAR----RLA-CDVIVDAFCGCGGNAIQFANTCGRVIAVDIDAEKLAMAKHNAGIYGVAHKIEFIHADFLQFAAS---TKLRPNVVFLSPPWGGPDYQKQATFDIETGLLPVGASQLMQLSRSLASDVAFFLPRNANMKQVVALS----GVGQQCEVEHNYLDTRMVALTAYYGKGIIKGSVGEDE-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12052-1", "uniprot_id": "TGS1_YEAST", "id": "Q12052-1", "name": "Trimethylguanosine synthase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGRTFIHASKIKHAARKRKHHSNFR------------------------------------TLIKLLNNDAYKIESSKPLKNGK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LFKYWKNRRRLFSKIDSASIYMTDELWFSVTPERIACFLANFVKACMPNAERILDVFCGGGGNTIQFAMQFPYVYGVDYSIEHIYCTAKNAQSYGVDDRIWLKRGSWKKLVSKQKLSKIKYDCVFGSPPWGGPEYLRNDVYDLEQHLKPMGITKMLKSFLKLSPNVIMFLPRNSDLNQLSRATRKVLGPFAKCKVLYVKENGYMKGIFCMWGECFFNYEPASTENSRRESSEKEELSSENEELSKRKKHESTTTTKDNTVDIYDVNG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . . : : . * . : : *** :* ***::*.. * : * *******:** * : : ::*.*** ***:**** * .:* . :: : :** **: .:* : ..: :.. :: : ** *******:* .:::. : * :::: :: :: *****:::.*: : * : :: : : : . :*. : ", "identical_positions": 58, "similar_positions": 76, "identity": "6.2%" }, { "cls_id": "homologset.agr.SGD:S000006081", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BMJ2-1", "uniprot_id": "SYLC_MOUSE", "id": "Q8BMJ2-1", "name": "Leucine--tRNA ligase, cytoplasmic", "aln": "---MAGRKGTAKVDFLKEIEKEAQQKWEAEKVFEVSASRLEKQ--------KQSSKGKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKGKSCLFPFGLHCTGMPIKACADKLKREIELYG-CPPDFPEEEEEEEESSAKPGDIVVRDKAKGKKSKAAAKAGSSKYQWDIMKSLGLSDDDIVKFSEAEHWLDYFPPLAVQDLKTIGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLVKLKVLEPYPSKLSGLKG-------KNIFLVAATLRPETMFGQTNCWVRPDMKYIGFET-ANGDIFICTQRAARNMSYQGFTKHNGVVPVVKELMGEEILGASLSAPLTCYKVVYVLPMLTIKEDKGTGVVTSVPSDSPDDLAALRDLKKKQALRTKFGIRDDMVLPFEPVPVLEIPGIGNLPAVTVCDELKIQSQNDREKLAEAKEKLYLRGFYDGVMLVDGFKGQKIQHVKKTIQKNMIDAGDALIYMEPEKQVMSRSADECVVALCDQWYLDYGDENWKKQTFQCLKNMETFCEESRKNFEASLDWLQEHACSRTYGLGTRLPWDEQWLIESLSDSTIYMAFYTVAHLLQGGDLNGQAESPLGIRPQQMTKDVWDYVFFKDAPFP-KTQIPKEKLDQLKQEFEFWYPVDLRASGKDLIPNHLSYYIYNHVAMWPEQSDKWPVSVRANGHLLLNSEKMSKSTGNFLTLSQAVDKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMLASCSSLRSGPADSFNDRVFASEMNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELA-TEGMHRELVFRFIEVQTILLTPFCPHLCEHIW-TLLGKPDSIMHASWPVAG-PVDESLIRSSQYLMEVAHDLRLRLKNYMMPAKGKKTDKQP---AQRPSHCTIYVAKNYPVWQHITLTTLRSHFEANNGKLPDNKVIASELGSLPELKKYMKKVMPFVAMIKENMEK-KGPRVLDLELEFDEQAVLMENIVYLTNSLELEHIEVKFAS--EAEDKVREECCPGKPLNVFRTEPGVPVSLVNPQPSSGHFSTKIDIRQGDSCESIIRRLMKTDRGIKDLSKVKLMRFDDPLLGPRRVPVLGREHSEKTLISENAVFHVDLVSKKVHLTENGLRTDIGDTMVYLVH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2J5-1", "uniprot_id": "SYLC_HUMAN", "id": "Q9P2J5-1", "name": "Leucine--tRNA ligase, cytoplasmic", "aln": "---MAERKGTAKVDFLKKIEKEIQQKWDTERVFEVNASNLEK----------QTSKGKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKGKCCLFPFGLHCTGMPIKACADKLKREIELYG-CPPDFPDEEEEEEETSVKTEDIIIKDKAKGKKSKAAAKAGSSKYQWGIMKSLGLSDEEIVKFSEAEHWLDYFPPLAIQDLKRMGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLLKLKVLEPYPSKLSGLKG-------KNIFLVAATLRPETMFGQTNCWVRPDMKYIGFET-VNGDIFICTQKAARNMSYQGFTKDNGVVPVVKELMGEEILGASLSAPLTSYKVIYVLPMLTIKEDKGTGVVTSVPSDSPDDIAALRDLKKKQALRAKYGIRDDMVLPFEPVPVIEIPGFGNLSAVTICDELKIQSQNDREKLAEAKEKIYLKGFYEGIMLVDGFKGQKVQDVKKTIQKKMIDAGDALIYMEPEKQVMSRSSDECVVALCDQWYLDYGEENWKKQTSQCLKNLETFCEETRRNFEATLGWLQEHACSRTYGLGTHLPWDEQWLIESLSDSTIYMAFYTVAHLLQGGNLHGQAESPLGIRPQQMTKEVWDYVFFKEAPFP-KTQIAKEKLDQLKQEFEFWYPVDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDKWPTAVRANGHLLLNSEKMSKSTGNFLTLTQAIDKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMVANWDSLRSGPASTFNDRVFASELNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELA-VEGMHRELVFRFIEVQTLLLAPFCPHLCEHIW-TLLGKPDSIMNASWPVAG-PVNEVLIHSSQYLMEVTHDLRLRLKNYMMPAKGKKTDKQP---LQKPSHCTIYVAKNYPPWQHTTLSVLRKHFEANNGKLPDNKVIASELGSMPELKKYMKKVMPFVAMIKENLEK-MGPRILDLQLEFDEKAVLMENIVYLTNSLELEHIEVKFAS--EAEDKIREDCCPGKPLNVFRIEPGVSVSLVNPQPSNGHFSTKIEIRQGDNCDSIIRRLMKMNRGIKDLSKVKLMRFDDPLLGPRRVPVLGKEYTEKTPISEHAVFNVDLMSKKIHLTENGIRVDIGDTIIYLVH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQR8-1", "uniprot_id": "Q9VQR8_DROME", "id": "Q9VQR8-1", "name": "leucine--tRNA ligase", "aln": "-MATTERKGTFKVEYLQKIEREVQQRWEAERVHESDAPTAPK----------KRQAEKFFVTFPFPYMNGRLHLGHTFSLSKAEYSMRYHRLKGRRVLWPFGFHCTGMPIKACADKLTRELEQFG-FPPQFP-ETEEVVPVAAEAASEVPKDKSKGKKSKAVAKTGAAKYQWQIMQSLGLKDEEIKDFANAEHWLNYFPPLAVQDLKRIGVHVDWRRTFITTDANPYFDSFVRWQFNHLKERGKIMYGKRYTIYSPKDGQPCMDHDRSSGEGVGPQEYTLIKMKVLE-VPKALSSIK--------QPIFMVAATLRPETMYGQTNCWLHPDIKYIAWQANKNNEVWVSTRRAARNMTYQGFTAVEGEIKVLAEVTGQDLLGVPLSAPLTKHKVVYSLPMLSIKEDKGTGVVTSVPSDSPDDYAALVDLQKKEAFRQKYGLKDEMVLPYEPIPIIEVPTLGKLSAVHAYETLKIQSQNDKDKLAEAKEMCYLKSFYDGVMLVGAFAGRKIQDVKKDLQKRLVDANEADVYYEPEKTIMSRSADECVVALCNQWYLNYGEPEWQAQATKILHGMETFHEEARNNFEACLNWLHEYACSRTYGLGTKLPWDDKWLIESLSDSTIYMAFYTVVHLLQGGTFRGEKPGPFGIKPSDMTGEIWDYIFFKETPLPKKTAIKQEHLAVLRREFEYWYPMDLRVSGKDLIQNHLTFCLYNHAAIWPNDENKWPKGMRVNGHLLLNSAKMSKSDGNFLTLTEAVDKFSADGMRLCLADAGDSVEDANFVESTADAGILRLYTFIEWVKEMLENRSSLRKGTDKTFNDQVFLSELNLKTQQTDENYRKMLFKEALRSGFYELQLARDKYRELCGANGMHEDLVLEFIRRQALLVSPICPHMAEHVW-GLLGNKESIVHARWPEVG-AINEVDILCSEYLMEAAHSFRLNLKNLLQIKGKAGKDKSVNVQAAKPNRGLVWVAKTYPPWQCCVLDTMKELFNKSQ-ALPDNKVIAATLQQKAELKKFMKRVMPFAQMIREKVESGKGVAALAVTLEFDERQVLISNLEYLKNTLDLDVLEIKYTDDPSAPEKTREEVRPGSPFISFSVAPNVSVELTNPIERSSLFQVNTVISEGDTVQSLREKLSKIIGLKTDAATLKIWRYEDPVLGPRKIPNFEDYKAGKSVLGE-GNFVLDVENKKVSLEQAGKLTEVGRNLIYVVD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P26637-1", "uniprot_id": "SYLC_YEAST", "id": "P26637-1", "name": "Leucine--tRNA ligase, cytoplasmic", "aln": "MSSGLVLENTARRDALIAIEKKYQKIWAEEHQFEIDAPSIEDEPITMDSEELHRTYPKFMSSMAYPYMNGVMHAGHCFTLSKVEFSIGFERMNGKRALFPLGFHCTGMPILACADKLKREAELFGKNFDNVPAEEEEIKEETPAEKDHEDVTKFKAKKSKAAAKKGRGKYQFEIMLQLGIPREEIIKFADAKYWLTYFPPLCESDCTSLGARIDWRRSFVTTDANPYYDAFIRWQMNKLKAAGKIKFGERYTIYSEKDGQACMDHDRQSGEGVTPQEYIGVKIEALEFADDAAKIIDSSSDLDKSKKFYFVAATLRPETMYGQTCCFVSPTIEYGIFDA--GDSYFITTERAFKNMSYQKLTPKRGFYKPIVTVPGKAFIGTKIHAPQSVYPELRILPMETVIATKGTGVVTCVPSNSPDDYITTKDLLHKPEY---YGIKPEWID-HEIVPIMHTEKYGDLTAKAIVEEKKIQSPKDKNLLAEAKKIAYKEDYYTGTMIYGPYKGEKVEQAKNKVKADMIAAGEAFVYNEPESQVMSRSGDDCIVSLEDQWYVDYGEESWKKQAIECLEGMQLFAPEVKNAFEGVLDWLKNWAVCRTYGLGTRLPWDEKYLVESLSDSTIYQSFYTIAHLLFK-DYYGNEIGPLGISADQMTDEVFDYIFQHQDDVK-NTNIPLPALQKLRREFEYFYPLDVSISGKDLIPNHLTFFIYTHVALFP--KKFWPKGIRANGHLMLNNSKMSKSTGNFMTLEQTVEKFGADAARIAFADAGDTVEDANFDESNANAAILRLFNLKEWAEEITKE-SNLRTGEITDFFDIAFEHEMNALIEKTYEQYALTNYKNALKYGLFDFQAARDYYREAS--GVMHKDLIARYIETQALLLAPIAPHFAEYIYREVLGNQTSVQNAKFPRASKPVDKGVLAALDYLRNLQRSIREGEGQALKKKKGKSAEIDA----SKPVKLTLLISESFPEWQSQCVEIVRKLFSEQT--LDDNKKVREHIE-----PKEMKRAMPFISLLKQRLANEKPEDVFERELQFSEIDTVKAAARNVKKAAQALKIAEFSAISFPYGAKTGKDIFTG---EEVEIPP-VTKIVENAVPGN----------PGVVFQNI--------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* : : * **:: *: * *: .* .*. . : *:: ::.:***** :* ** *:*** *::: :.*::*: *:*:*:******* ******.** * :* :.* * ** : . * *.*****.** * .***: ** .**: ::* .*::*::** *****. .* . :* ::****:*:***.***:*:*:***: *: .** :*:****** ****.******.:**** **** :*::.** . . :. : :::**********:*** *:: * ::* ::: ... :: *.:* :**:** :* .* : : *: ::*. : ** : : : *** :: *******.***:**** : ** :* :*:: : : .* :*::. *.*.* : **** :*:: *****: * ..:* * *: . : *.*::..*: :: :: *.:* :* ***. :****.*:*:*:* :***::**: .*: *: : *..:: * * :. **. *.**:: * .*******:****:::*:********* :***:.*** *: .*:** ..:** :::**:* :: . :* * * *::***::**:*: *****: ***:: :*.*.*::* .. ** .:*.****:**. ***** ***:** ::::**.**. *:.:*****:****** *: *:*.****:. **.:*: . ..**.* * * .* *:* :* ::* :*:**: *::::* *:* *** . **.:*: .:*. *::*::*:.**:.*::: :**: *: :* :* .. .::: : . :** : :.:* : : : . :* : : :::.:* ** : ::. *. . * *** : : * **:.*** ::::.: . : *:*.* .: :.:: : : : * :: .* . * *. : *. . * :.: ", "identical_positions": 391, "similar_positions": 346, "identity": "32.37%" }, { "cls_id": "homologset.agr.SGD:S000006082", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K1D2-1", "uniprot_id": "A0A0G2K1D2_RAT", "id": "A0A0G2K1D2-1", "name": "Rap1 GTPase-GDP dissociation stimulator 1", "aln": "--MDNLSDALKKLKITAADKTEGSLEGCLDCLLQALAQNNAETSEKIQGSGILQLFANLLTPQASCTAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSK-----DQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLCGRADPAN--------EKLLTVFCGMLMNYSNENDSLQAQLINMGVIPTLVKLLGIHCHNAALTEMCLVAFGNLAELESS--KEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQ-KVDSTKEDDLAELKTASDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNSQQLQLAGALAIANFARNDGNCIHMVDNGIVEKLMDLLDR-HVEDGNVTVQHAALSALRNLAIPVVNKAKMLSAGVTETVLKFLKSEMPPVQFK-LLGTLRMLIDAQAEAAEQLGKNAKLVERLVEWCEAKDHAG-VMGESNRLLSALIRHSKSKDVIKTIVQ------------------------------SGGIKHLVTMATSEHVIMQNEALVALALIAALELGPAEKDLASAQLVQILHRLLADERSAPEIKYNSMVLICALMGSEALHKEVQDLAFLD-VVSKLRSHENKS------------------VAQQASLTEQRLTVQS------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q912-1", "uniprot_id": "GDS1_MOUSE", "id": "E9Q912-1", "name": "Rap1 GTPase-GDP dissociation stimulator 1", "aln": "--MDNLSDTLKKLKITAADRTEGSLEGCLDCLLQALAQNNAETSEKIQGSGILQLFANLLTPQASCTAKVADIIAEVAKNEFMRIPCVDAGLISPLVQLLNSK-----DQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLCGRTDPAS--------EKLMTVFCGMLMNYSNENDSLQAQLISMGVIPTLVKLLGIHCHNAALTEMCLVAFGNLAELESS--KEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQ-KVDSNKEDDVAELKTASDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDGNCIHMVDNGIVEKLMDLLDR-HVEDGNVTVQHAALSALRNLAIPVVNKAKMLSAGVTETVLKFLKSEMPPVQFK-LLGTLRMLIDAQAEAAEQLGKNAKLVERLVEWCEAKDHAG-VMGESNRLLSALIRHSKSKDVIKTIVQ------------------------------SGGIKHLVTMATSEHVIMQNEALVALALIAALELGPAEKDLASAQLVQILHRLLADERSAPEIKYNSMVLICALMGSESLYKEVQDLAFLD-VVSKLRSHENKS------------------VAQQASLTEQRLTVES------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52306-1", "uniprot_id": "GDS1_HUMAN", "id": "P52306-1", "name": "Rap1 GTPase-GDP dissociation stimulator 1", "aln": "--MDNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSK-----DQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLCSITDPAN--------EKLLTVFCGMLMNYSNENDSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESS--KEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQ-KVDSDKEDDITELKTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEKLMDLLDR-HVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQFK-LLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAG-VMGESNRLLSALIRHSKSKDVIKTIVQ------------------------------SGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLD-VVSKLRSHENKS------------------VAQQASLTEQRLTVES------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z6S7-1", "uniprot_id": "GDS1_DROME", "id": "A1Z6S7-1", "name": "GTPase-GDP dissociation stimulator vimar", "aln": "MATAEIDDLIEKLKTTSVSPAN-----TTNLLCEISATKDPKLFDKHELAECFLGLT--KCDDTNVRKEAAKCIAEITKSEVQRKKFTKRNIIAAFLECLRQVPTSDGSMELPIQICRALGNICYLNDEARDLILELEGDAVLLRLLDITTIEDVANA--------AQFIKVRGGLLSNYLLGGEGLAKRAMELGVMKKLQGIIDIGASNVEQHEDLLLNTLPLLSILTENVSDLNFDSSLNIQLSRILAASTNPDLAEMCLELLHYQAESDEVKLILAKDGLCETIYNLLEKYKTLASTSEARALMKLACELIVLILTGDDSMHYLYTTP---LLKNMVDWLDSTDIDLLTTGVLALGNFARTDSHCIYFVEQQTMNKLLEVLAKNNGVKDDVRLQHALLSALRNLVIPKPNKNAVIQAGLVQTILPMLEIHQPPVVFK-LLGTLRMTVDGQEKLALELLKNKTLIEQLVHWSKSSDYAG-VTGESLRLMAWLIKHAYLSKIAYALPRKGDAPAEQIADKIPLTQDYDRSSLSEFLANEGTVEAMVSMLTAQHLVMQNEALIALCILSVVYLSQPSEAAQAQLLQDELVKCEVGKKLAELISKSSDTMTKEIVEN--LQNCVNLLKSSEQLVAHLEQHNINE------------------LLKSIPILTEYCTL--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39011-1", "uniprot_id": "GDS1_YEAST", "id": "P39011-1", "name": "GTPase-GDP dissociation stimulator BEM4", "aln": "---MDYEEILFGLQP----------------ILNASSIKDVPMNDVYLGSYLAVMDQLAVSLREPSNRDIVGKTGLLLNLVRVLEQALDICFHDTSISINDKIA----FYEISSEVIRCIANAIIDNDDNREILLDSGGKKLLNYYIGGVLQLDEISSDKSEDSLVDKLQMRSVVLLRNFCIGNLKYTENLAPFIRGPLFVLLKTTQYSYLSSPEKVVLGSDLLNDILKVNYSNVQISDLFFLSQYIKKISSNVQNKELQAMEDGAVEAYSNTETQKFAGQGNQEYIEKEEED----DEEDVNCELLLNLSTCLETIVAKDETINFTNEEQLVLSMQKNLILSLVCLESKTFNNKLIVMRRLISCAGNISANLTNSNKREQSLCIETIKSSASSYALAAALMILCNSVASKSDAVALLKLISLSELIQVGSLLQDPLQYQGFLDLLRKLLNLENTMWLDIKDLFTLFQIMRRCHEQTKYYNNLRSLLTNLLNKTLTVLPSSKIHNSISSD-----------------------PTIISFIAEHGTLTSCIAMDKLLVSKKALPKEAITSLWDSIFKFQNLGQAEQLSISDLFHITKTVGIYLKDSSVTADVNPIENILFKDYIQKLTLILETILSFKENKDKGSESCFNNGKFIAGIILNIVKNTKCLTPEEQNLEALAKSFF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: : *: : : : :: : : . . . : : . : . :. . *: : *.:.* ..: *. : : * :: : :: :* *: . . : : : * :: * .: . .: . : . . : :* * .: . :. * * : : :. . : . : :: *:::: ::. : . . * : . . . * :: .: . . . * * * * . . : ::. . :: . . *: :: :*. ** :: : :: . .*.: : . : ..: . : . .*: : ..: :: . :.: : :::::.::** .: : : . : . :. .* . : . : . :: * : :..:: : : : : : .: ", "identical_positions": 31, "similar_positions": 180, "identity": "4.54%" }, { "cls_id": "homologset.agr.SGD:S000006083", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UF25-1", "uniprot_id": "STIMA_MOUSE", "id": "Q3UF25-1", "name": "Store-operated calcium entry regulator STIMATE", "aln": "MQGPGGNVSRGLPSGPASTVASGAGRCESGALMHSFGIFLQGLLGVVAFSTLMLKRFREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLADLTE---------------EDPCSLYLINFLLDATVGMLLIYVGVRAVGVLVEWQQWESLRFGEYGDPLQCG---------AWVGQCALYIVIMIFEKSVVFIVLLILQWKKVALLNPIE-----NPDLKLAIVMLIVPFFVNAFMFWVVDNFLMRKGKTKAKLEERGANQDSRNGSKVRYRRAASHEESESEILISADDEMEESDAEEDLR-----RPVKKK-HRFGLPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TSW6-1", "uniprot_id": "STIMA_RAT", "id": "Q7TSW6-1", "name": "Store-operated calcium entry regulator STIMATE", "aln": "MQGPGGNVSRGLPGGPASTVASGAGRCESGALMHSFGIFLQGLLGVVAFSTLMLKRFREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLADLTE---------------EDPCSLYLINFLLDATVGMLLIYVGVRAVGVLVEWQQWESLRFGEYGDPLQCG---------AWVGQCALYIVIMIFEKSVVFIVLLILQWKKVALLNPIE-----NPDLKLAIVMLIVPFFVNAFMFWVVDNFLMRKGKTKAKLEERGANQDSRNGSKVRYRRAASHEESESEILISADDEMEESDAEEDLR-----RPVKKK-HRFGLPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86TL2-1", "uniprot_id": "STIMA_HUMAN", "id": "Q86TL2-1", "name": "Store-operated calcium entry regulator STIMATE", "aln": "MQGPAGNASRGLPGGPPSTVASGAGRCESGALMHSFGIFLQGLLGVVAFSTLMLKRFREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLADLTE---------------EDPCSLYLINFLLDATVGMLLIYVGVRAVSVLVEWQQWESLRFGEYGDPLQCG---------AWVGQCALYIVIMIFEKSVVFIVLLILQWKKVALLNPIE-----NPDLKLAIVMLIVPFFVNALMFWVVDNFLMRKGKTKAKLEERGANQDSRNGSKVRYRRAASHEESESEILISADDEMEESDVEEDLRRLTPLKPVKKKKHRFGLPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12042-1", "uniprot_id": "YP162_YEAST", "id": "Q12042-1", "name": "Vacuolar membrane protein YPL162C", "aln": "-----------------MYVSNGKDTCQ---LLGPVSLFVQTLMGMTAVIVLLVKRN--YEHPRRKMIVWSYDIGKQIIGSLGIHFLNLGISILKKRRRSLFAITAKGNDDEDQCDWYFLNLLLDTTVGIPILWLCLYIIEKVLKSLHFQNIESGNYFPSKTVGSHPRKPLFSAFVKQLLIFIVGLGVMKFCVFLILNYLEDLAYWFADLILGWSDSWPNFQVFLVMFVFPILLNCFQYFCVDNVIRLHSESLTITNAENFETNTFLNDEIPDLSEVSNEVPNKDNNISSYGSII----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:.* . *: *: ...:*:* *:*:.*. .*::** :* ** :* * .** ** * *** *: :: *.: ** *. *::*:***:***: :::: : : ::: :::.:. *:* . * *:* * ::** : . * **::* *: : : * *:::: :**::.*:::*.: :: ***.: :.:: : : .. : :: ..:: .*:* .:.: **: ..: ", "identical_positions": 64, "similar_positions": 100, "identity": "19.81%" }, { "cls_id": "homologset.agr.SGD:S000006085", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADG4-1", "uniprot_id": "D4ADG4_RAT", "id": "D4ADG4-1", "name": "", "aln": "---MIRCLSDEVQAKLRSGLALSSLGQCVEELTLNSIDAEATCVAIRVNMETFQVQVIDNGLGMAGDDVEKVGNRYFTSKCHSVRDLENPTFYGFRGEALASIADMASAVEISSKKSTTLKTFVKMFQNGKALAA----------READLTRPSVGTTVTVYNLFYQFPVRR---KSMDPRLEFEKVRQRVEALSLMHPSISFSLRNDV-----------SGSMILQLPKTKDICSRFCQIYG-LGKSQKLREIHYKYKEFEFNGYISSEAHYNKNMQFLFVNRRLVLRTKLHKLIDFLLRKESIICRPKNGSASRQMNSSPRHRSASELHGIYVINVQCPFCEYDVCIEPAKTLIEFQNWDTVLICVQEGIKKFLKQEKLFVELSSEDIKEFNEDNGFSLIGTTLQTQS-THEKCDQSSFQEACNNILDSYEMFNLQSKAVKRIATLENRTTQNSGDSGAIRKKTEDS--YTYESDDLGHRKTVESALYNSD-SAYLGSRMSEEDIAKTSHAGENEKWKKSLLENRTSERPHETSPKMFSSPIQTHHPLEESEADLEIEMKSSTVNVMAANIPPNSEIQSQLEQLEDAPEVECQPLPFETTLLRAQGTLKKKER-KKELSSHGRVNVFSYGQVKLCSTGFITHVVQREPAKSPETEQLFKNYARPGPVSAQEAFGNRTHHASETPDSSSLTSTLSKESTQPPHKRFCRTNTGYGTENKPVATDDNLALFQGSRKESHTDCFLPDTT-SFPWCRNVSGGYKKKGKVGSF-KHVVRRKLSLRSQIGSLEKFKRQYGKVNNSLAAEEDNDTDFRTHLEPHNEPDVLLKDKSLSDMSDGGEITPSEHSDG---CQPLRPILYPET--LSKED--RLEQRPSLRESPITLAELLHGNRKPSEVKKSTEALASKLSRLK-DSEKEMQTMEMAGPVSERPDSDPSWKDNSQCARLDLNFCELYKNKLEKTESEVLPMPDSAPEDDSINKNSVLCSN-SVTDDREKPETSLLLPCSDSKIS-KDSDVLIRVSEQQSGSPDSASREVTRQVEDSAGSQCGICSQSHGFKARSCSDNEESSTHSMDWQQHFDVTLGRTVYINRMTGLSTFVAP-TDDIQTPCTKDLTTVAVDVLLGNGVQYRCHPFRSDLVLPFLPRAQEERTRRR-HNRDAVD--AAAVSEPLQSLFSEWSNPVFARYPEVAVDVSSGQAGSLAVKIHNVLYPYRFTKEMIHSVQVLQQVDNKFIACLMSSRTDGSGQAEILVGFVGGNLLVLVDQHAAHERVRLEQLITDSYEKQAPQSAGRKKLLSSTIIPPLAITVSEEQRRLLRSYHKHLEDLGLELLFPD--ASDSSILVGKVPLCFVEREANELRRGRSPVTKSIVEELIREQLELLQTTGG------------IQGTLPLTVQKVLASQACHGAIKFNDRLSLEESCRLIEALSLCQLPFQCAHGRPSMLPLADLDHLEQEKQV-KPNLTKLRKMAHAWHLFGKAEGCDTKQEPQQPVPPCEPP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A1Y7VMP7-1", "uniprot_id": "A0A1Y7VMP7_MOUSE", "id": "A0A1Y7VMP7-1", "name": "", "aln": "---MIRCLSDDVKTKLRSGLAISSLGQCVEELTLNSIDAEATCVAIRVNMETFQVQVIDNGLGMAGDDVEKVGNRYFTSKCHSVRDLENPAFYGFRGEALASIADMAGAVEISSKKNTTLKTFVKMFQNGKALAT----------HEADLTRPSVGTTVTVYNLFYQFPVRR---KSMDPRLEFEKVRQRVEALSLMHPSISFSLRNDV-----------SGSMVLQLPKTKDICSRFCQIYG-LGKSQKLREIRFKYKEFEFSGYISSEAHYNKNMQFLFVNRRLVLRTKLHKLIDFLLRKESIICRPKNGSASRQMNSSPRHRSASELHGIYVINVQCPFCEYDVCIEPAKTLIEFQSWDTVLICIQEGVKRFLKQEKLFVELSGEDIKEFNEDNGFSLFGTTLQTHVSTHEKCDQSSFREACNKILDSYEMFNLQSKAVKRIATLENKTRQNPGDSETIRKKTVGSL-YTDASDGPCYSKSVESVLQDSNNSAYLEPRVSEEEVAKTSHSGENEKWKKSFLENKTSGRIHETSPKMFSSPIQMHHLLEEREADLEMQTISSTVNVMAANIPQNNDIPSQLEKWKDAPEVGCQPLPFETTLLRVRGTQRKKERRKKEPSSRGRVNVFSYGQVKLCSTGFITHVVQSEHAKSTETEHSFKNYARPGPVSAQETFGKRTHHAIETPDSSDLTSTLSKESSQPPNKRFCRTNTGYGTENKPVATDDNLALFQESCKESHTDRLLPDAS-SFPWCRYVSDGCRKIDKRGSF-KQVVRRKLSLRSQVGSLEKFKRQYGKVSSSLDTEKDNNTEVRTHLDPQNEPDVLLKDKSHLDMSDGCEITTVEHSET---CQPLSPILYPEKILFSKED--RLEQMPHLRESPITLEELSHCNRK-ADVEKSAASLASKLSKLK-DSEKEMQTVGMTGHTSELPDSNPSWKDNSQCTRLDLDFCELLKNKLEKIESDMLPMADSATEDGPINKNSELHPN-NTTDDTEKPETPLLFPCNDSKIS-RDSDVLIRTSEQPTGNPDSVGKVIMSQVEDGIGSQGGVCPQGDESKARSCSKNE-PNAHCMDWQQHFDVTLGRMVYINRMTGLSTFVAP-TDDLHTACTKDLTTVAVDVLLGNGAQYRCHPFRSDLVLPFLPRAQEERTMLR-HNSNAVDAAAAAVSEPLQSLFSEWSNPVFARYPEVAVDVSSGQAESLAVKIHNVLYPYRFTKEMIHSVKVLQQVDNKFIACLMSTRMDEDGR-------TGGNLLVLVDQHAAHERIRLEQLITDSYEKQDPQSAGRKKLLSSTIIPPLAITVSEEQRRLLRSYHKHLEDLGLELLFPD--ASDSLILVGKVPLCFVEREASELRRGRSTVTKSIVEELIREQVELLQTTGG------------IQGTLPLTVQKVLASQACHGAIKFNDRLSLEESCRLIEALSLSQLPFQCAHGRPSMLPLADLDHLEQEKQV-KPNLAKLRKMVRAWHLFGKTE-----QNLQQPIRPCEPP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHC1-1", "uniprot_id": "MLH3_HUMAN", "id": "Q9UHC1-1", "name": "DNA mismatch repair protein Mlh3", "aln": "---MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFGMGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTFVKLFQSGKALKA----------CEADVTRASAGTTVTVYNLFYQLPVRR---KCMDPRLEFEKVRQRIEALSLMHPSISFSLRNDV-----------SGSMVLQLPKTKDVCSRFCQIYG-LGKSQKLREISFKYKEFELSGYISSEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTPELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGEDIKEFSEDNGFSLFDATLQKRVTSDERSN---FQEACNNILDSYEMFNLQSKAVKRKTTAENVNTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKD-SSCSESKMLEQETIVASEAGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAANILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEK-KKESSNCGRRNVFSYGRVKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLASTLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWYRHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTTNLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDCLEQQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLK-GSERETQTMGMMSRFNELPNSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTTENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGICFQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAP-TEDIQAACTKDLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVD--DTVSSESLQSLFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFIACLMSTKTEENGE-------AGGNLLVLVDQHAAHERIRLEQLIIDSYEKQQAQGSGRKKLLSSTLIPPLEITVTEEQRRLLWCYHKNLEDLGLEFVFPD--TSDSLVLVGKVPLCFVEREANELRRGRSTVTKSIVEEFIREQLELLQTTGG------------IQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRLIEALSSCQLPFQCAHGRPSMLPLADIDHLEQEKQI-KPNLTKLRKMAQAWRLFGKAE-CDTRQSLQQSMPPCEPP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B931-1", "uniprot_id": "A0A8M2B931_DANRE", "id": "A0A8M2B931-1", "name": "", "aln": "---MIKSLPINVQAQLRSGVAIFSLQQCVEELILNSIDAGATCVAVKIDIEACKLQVIDNGSGMCLEDMEKVGLRYNTSKCSSLEDLDNLHFYGFRGEAISSIVSLAEMVEISSRTKQSVKTYVKSFNETNALEV----------FEAQTVRPSAGTTVSVYNLFHNMPVRR---KRMDPVLETERIRQRVEAISLMHPSVSFTVKKEN-----------SAHMMVQLSKTSSTYYRFVQIHG-LNRAQKLGEVNYEHEQFQITGHIGREGHYNNSLQFLFVNERLLLKTRIHKTLNCLLKRVSGAARQNNSPTSYPVTSSPKQKGGYDLHGIYVINIKCHYSEYDICLEPAKSLIEFKDWDNVLICIEEGVKAFLTKENLVSELN-----TISNDG---------------------------------------LPCSPVRNAESSEKQKRSSEETN-----------------------EACETMIEKND---------------------------------------------------------------------SSVVDVADG--VQMLEQESIYTESDEGKALQSEDLPFQTTLVGAAEINNNHEE----------------DENAVCSN--ISHTDS--------------------PLAVNKNVMGSKSHKISLPEAQDSLQKFYTPNKTSPKKRRMPLN----------DTEEEKHVFYGGPSKT--------------------------------FKATPPRKLTLSFETGSLDKFKRLFGK-----EAEKKQPSTEKTSLLNPNPNDRFVGSTSCLD-------------------DLHHPVLRNSS------------GHPTTHRS----TESSSLNKK------NKISLAAKCSYLKQDKELCRDSNFLKRDLSSFPPSQDSCFKELEKTLLDEDVLFGSSGIVDSVD---FPLIEQDTALPSVAEESHLFNN-----------NVTFFIGNESSVD-----------------------------EASVASQRDPQHSIAGNEGQTTNESVESIPVSNSWLAHYDSWLGKLVYINQVTGLSKYNSPPMEETQVPCTTDVTNMAVSVISKAGFEYRCYPFQSDIVLPFLPKPRAERAFNS--GTDSRE--DAQAPDSLSTLFSEWHNPVFIRPPEVAVDVTSGQAEGLAVKIHNILFPYRFTKNMIHTMRVINQVDKKFLACLINTAGQNTSES----STDEGNLLVLVDQHAAHERVRLEGLIADSYE-DDPDTPGKKRLCSSRVTPPLEINVTEEELRLLRSCQGFLRGLALDVRFPK--SESLSVFLESLPACFIEKESTELRRGRRSVIKTIAEDYLREHIELLRSTGR------------VRGILPLTVHNVLASQACHGAIKFNDVLNKEECCSLVSSLSSCRLPFQCAHGRPSIVPLADLHHLEEQQDIPKPNLKKLRRMYKSWQLYGQNQ------YFAQNKA-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12083-1", "uniprot_id": "MLH3_YEAST", "id": "Q12083-1", "name": "DNA mismatch repair protein MLH3", "aln": "MSQHIRKLDSDVSERLKSQACTVSLASAVREIVQNSVDAHATTIDVMIDLPNLSFAVYDDGIGLTRSDLNILATQNYTSKIRKMNDLVTMKTYGYRGDALYSISNVSNLFVCSKKKDYNSAWMRKFPSKSVMLSENTILPIDPFWKICPWSRTKSGTVVIVEDMLYNLPVRRRILKEEPPFKTFNTIKADMLQILVMHPMISLNVQYTDKLRINTEVLFRSKNITEGLTKHQQMSQVLRNVFGAIIPPDMLKKVSLKFNEYQIEGIISKMPVGLKDLQFIYINGRRYADSAFQGYVDSLFQAQDFGEKGMSLLKTKSVGKPYRS------HPVFILDVRCPQTIDDLLQDPAKKIVKPSHIRTIEPLIVKTIRSFLTFQGYLTPDK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDSSFEIVNCSQKTATLPDSRIQISKR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NQVLNSKMKIAR----------------------------------INSYIGKPAVN--------------------------------------------------------------------------------------------------------------------------------GCRINNSTINYEKIKN-------------------------------------------IRIDGQKSRLR----------NKLSSRPYDSGFTEDYD-----------------------SIGKTITDFSISRSVLAKYEVINQVDKKFILIRCLDQSIHNCP-----------LLVLVDQHACDERIRLEELFYSLLTEVVTG------TFVARDLKDCCIEVDRTEADLFKHYQSEFKKWGIGYETIEGTMETSLLEIKTLPEMLTSKYNGDKDYLKMVLLQHAHDLKDFKKLPMDLSHFENYTSVDKLYWWKYSSCVPTVFHEILNSKACRSAVMFGDELTRQECIILISKLSRCHNPFECAHGRPSMVPIAELK------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: * :*. :*:* . ** ..*.*: **:** *. : : ::: .. * *:* *: .*:: :. : *** .:.** . **:**:*: .* .:: . *.:.. . * .. * . *.. **.* * ::::::**** * * : :: : : :*** :*:.:: * : *.* .. : ::.* : .: * :: :.::::: * *. :.:**:::* * : :: :: *:: . : . : : .. : : :::::::* *: :***.::: . .: : : :: **. : . . . . : .. .: .:: * :* . : : . . * . .. : ::: . . .: *:* : .* : : : ::: :: . .*::***:**: *********..**:*** *: . . : * * . : *: : :. .: . . : : .:* : .: : : : : : ::: : : . :* ..:::* *:**:.*: *.* *. :*. *:. ** .: **:*******::*:*::. ", "identical_positions": 122, "similar_positions": 238, "identity": "8.06%" }, { "cls_id": "homologset.agr.SGD:S000006086", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NB12-1", "uniprot_id": "SMYD1_HUMAN", "id": "Q8NB12-1", "name": "Histone-lysine N-methyltransferase SMYD1", "aln": "-MTIGRMENVEVFTAEGK----GRGLKATKEFWAADIIFAERAYS-AVVFDSLVNFVCHTCFKRQEKLHRCGQCKFAHYCDRTCQKDAWLNHKNECSAIKRYGK--VPNENIRLAARIMWRVEREGTGLTEGCLVSVDDLQNHVEHFGEEEQKDLRVDVDTFLQYWPPQSQ----QFSMQYISHIFGVINCNGFTLSDQRGLQAVGVGIFPN------------------------------------------------------LGLVNHDCWPNCTVIFNNGNHEAVKSMFHTQMRIELRALGKISEGEELTVSYIDFLNVSEERKRQLKKQYYFDCTCEHCQKKLKDDLFLGVK---DNPKPSQEVVKEMIQFSKDTLEKIDKARSEGLYHEVVKLCRECLEKQEPVFADTNIYMLRMLSIVSEVLSYLQAFEEASFYARRMVDGYMKLYHPNNAQLGMAVMRAGLTNWHAGNIEVGHGMICKAYAILLVTHGPSHPITKDLEAMRVQTEMELRMFRQNEFMYYKMREAALNNQPMQVMAEPSNEPSPALFHKKQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97443-1", "uniprot_id": "SMYD1_MOUSE", "id": "P97443-1", "name": "Histone-lysine N-methyltransferase Smyd1", "aln": "-MTIGSMENVEVFTSEGK----GRGLKATKEFWAADVIFAERAYS-AVVFDSLINFVCHTCFKRQEKLHRCGQCKFAHYCDRTCQKDAWLNHKNECAAIKKYGK--VPNENIRLAARIMWRVEREGTGLTEGCLVSVDDLQNHVEHFGEEEQKELRVDVDTFLQYWPPQSQ----QFSMQYISHIFGVINCNGFTLSDQRGLQAVGVGIFPN------------------------------------------------------LGLVNHDCWPNCTVIFNNGNHEAVKSMFHTQMRIELRALGKISEGEELTVSYIDFLHLSEERRRQLKKQYYFDCSCEHCQKGLKDDLFLAAK---EDPKPSQEVVKEMIQFSKDTLEKIDKARSEGLYHEVVKLCRECLEKQEPVFADTNLYVLRLLSIASEVLSYLQAYEEASHYARRMVDGYMKLYHHNNAQLGMAVMRAGLTNWHAGHIEVGHGMICKAYAILLVTHGPSHPITKDLEAMRMQTEMELRMFRQNEFMYHKMREAALNNQPMQVMAEPSNEPAPALFHKKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PGA4-1", "uniprot_id": "A0A8M1PGA4_DANRE", "id": "A0A8M1PGA4-1", "name": "[histone H3]-lysine(4) N-trimethyltransferase", "aln": "-MTVEKTDPVEVFGAGLK----GRGLRGTRDLSAGEVVFAEASFA-AVVLDSLSLQVCHSCFRRQVNPHRCAQCKFAHYCDRTCQRAAWDEHRKECSAIRNIGK--APNENVRLVARILWRIQKHTGLVSDSQLTTLDMLEDHLSRMTPEDLKELKVDVKTFYTYWPKKSK----AVGEDYVSHLFGVISCNGFTLSDQRGLQSVGIGLFPN------------------------------------------------------LCLVNHDCWPNCTVILNHGDQSALDASFHSSRRIELRALEPISAGQELTVSYVDFLSVSTDRQRLLQQQYYFDCKCEHCVNGTKDELMTAVKPTEDGKQPSAEVVKQLTDFSLQALVKIEAARAQGNFHEVIRICRECLEKQDPVFADTNVHVLRVLSTASEVLSFLQQFQEAAGYAQRMVDGYMKLYHPNNAQLGMAIMRAGVTHWHAGLIEAAHGLICRAYGILMITHGPHHPISKDLEAMRRQTEMELRMFKQNEHVYHSMREAALTSKPMSVAGEQVQIKA--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9CWR2-1", "uniprot_id": "SMYD3_MOUSE", "id": "Q9CWR2-1", "name": "Histone-lysine N-methyltransferase SMYD3", "aln": "----MEALKVEKFTTANR----GNGLRAVAPLRPGELLFRSDPLA-YTVCKGSRGVVCDRCLLGKEKLMRCSQCRIAKYCSAKCQKKAWPDHRRECSCLKSCKP-RYPPDSVRLLGRVIVKLMDEKP-SESEKLYSFYDLESNISKLTEDKKEGLRQLAMTFQHFMREEIQDASQLPPSFDLFEAFAKVICNSFTICNAE-MQEVGVGLYPS------------------------------------------------------MSLLNHSCDPNCSIVFN-------------GPHLLLRAVREIEAGEELTICYLDMLMTSEERRKQLRDQYCFECDCIRCQTQDKDADMLTGD-------------EQIWKEVQESLKKIEELKAHWKWEQVLALCQAIINSNSNRLPDINIYQLKVLDCAMDACINLGMLEEALFYAMRTMEPYRIFFPGSHPVRGVQVMKVGKLQLHQGMFPQAMKNLRLAFDIMKVTHGREHSLIEDLILLLEECDANIRAS---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H7B4-1", "uniprot_id": "SMYD3_HUMAN", "id": "Q9H7B4-1", "name": "Histone-lysine N-methyltransferase SMYD3", "aln": "----MEPLKVEKFATAKR----GNGLRAVTPLRPGELLFRSDPLA-YTVCKGSRGVVCDRCLLGKEKLMRCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKP-RYPPDSVRLLGRVVFKLMDGAP-SESEKLYSFYDLESNINKLTEDKKEGLRQLVMTFQHFMREEIQDASQLPPAFDLFEAFAKVICNSFTICNAE-MQEVGVGLYPS------------------------------------------------------ISLLNHSCDPNCSIVFN-------------GPHLLLRAVRDIEVGEELTICYLDMLMTSEERRKQLRDQYCFECDCFRCQTQDKDADMLTGD-------------EQVWKEVQESLKKIEELKAHWKWEQVLAMCQAIISSNSERLPDINIYQLKVLDCAMDACINLGLLEEALFYGTRTMEPYRIFFPGSHPVRGVQVMKVGKLQLHQGMFPQAMKNLRLAFDIMRVTHGREHSLIEDLILLLEECDANIRAS---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HNI9-1", "uniprot_id": "A0AC58HNI9_DANRE", "id": "A0AC58HNI9-1", "name": "[histone H3]-lysine(4) N-trimethyltransferase", "aln": "---MMEAVIMERFISEGK----GNGLRALREIKPGEVIYSCKPFA-FCVARDFLKTACQSCLKRGESLSRCSQCKTARYCSVQCQKQAWPDHKRECKCLKHLQP-RIPTDSVRLVARIIFKLLSQSE-SDQEELYSIAEHQSHLADMSEEKKEGLKHLCTTLQVYLAEENCDLSRLPSGLDPVSLLARVTCNCFSISDGE-LQDVGVGLYPRNMFSTIMLQDRAECVSLSPGRGWLCLTAQILHTSTGINRKLLENKSYAGVTMHGMSLLNHDCQPNCIMMFE-------------GKRLTLRAVRVIRSAEELTISYTDILAPSKDRRSQLQEQYHFRCECKRCSTEDKDCEMLSGE-------------KSAWTSIKDSIHHLEQLQSEQHWDELLKESQALLHRHSDVVPDRNIYMLRLLDLAMDACISLDDYETALEYGNRALGPYKLYFSDPHPSRAVELLRVGKLQHFLGRLEEARGSFTQAYSIMSVTHGAAHALTNQVQRRLSECQAELNTL---------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NRG4-1", "uniprot_id": "SMYD2_HUMAN", "id": "Q9NRG4-1", "name": "N-lysine methyltransferase SMYD2", "aln": "-MRAEGLGGLERFCSPGK----GRGLRALQPFQVGDLLFSCPAYA-YVLTVNERGNHCEYCFTRKEGLSKCGRCKQAFYCNVECQKEDWPMHKLECSPMVVFGENWNPSETVRLTARILAKQKIHPERTPSEKLLAVKEFESHLDKLDNEKKDLIQSDIAALHHFYSKHLG----FPDNDSLVVLFAQVNCNGFTIEDEE-LSHLGSAIFPD------------------------------------------------------VALMNHSCCPNVIVTYK-------------GTLAEVRAVQEIKPGEEVFTSYIDLLYPTEDRNDRLRDSYFFTCECQECTTKDKDKAKVEIR--KLSDPPKAEAIRDMVRYARNVIEEFRRAKHYKSPSELLEICELSQEKMSSVFEDSNVYMLHMMYQAMGVCLYMQDWEGALQYGQKIIKPYSKHYPLYSLNVASMWLKLGRLYMGLEHKAAGEKALKKAIAIMEVAHGKDHPYISEIKQEIESH----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R5A0-1", "uniprot_id": "SMYD2_MOUSE", "id": "Q8R5A0-1", "name": "N-lysine methyltransferase SMYD2", "aln": "-MRAEARGGLERFCSAGK----GRGLRALRPFHVGDLLFSCPAYA-CVLTVGERGHHCECCFARKEGLSKCGRCKQAFYCDVECQKEDWPLHKLECSSMVVLGENWNPSETVRLTARILAKQKIHPERTPSEKLLAVREFESHLDKLDNEKKDLIQSDIAALHQFYSKYLE----FPDHSSLVVLFAQVNCNGFTIEDEE-LSHLGSAIFPD------------------------------------------------------VALMNHSCCPNVIVTYK-------------GTLAEVRAVQEIHPGDEVFTSYIDLLYPTEDRNDRLRDSYFFTCECRECTTKDKDKAKVEVR--KLSSPPQAEAIRDMVRYARNVIEEFRRAKHYKSPSELLEICELSQEKMSSVFEDSNVYMLHMMYQAMGVCLYMQDWEGALKYGQKIIKPYSKHYPVYSLNVASMWLKLGRLYMGLENKAAGEKALKKAIAIMEVAHGKDHPYISEIKQEIESH----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5BJI7-1", "uniprot_id": "SMY2A_DANRE", "id": "Q5BJI7-1", "name": "N-lysine methyltransferase SMYD2-A", "aln": "-MKKEGIEGTERFLSPGK----GRGLKAIKHFKVGDLVFACPAYA-YVLTVNERGGRCECCFTRKEGLSKCGKCKQAYYCNVECQRGDWPMHKLECSAMCAYGENWCPSETVRLVARIILKQKHQTERTPSERVLTLRELEAHLDKLDNEKNEMNDTDIAALHHFYSRHLD----FPDNAALTELIAQVNCNGFTIEDEE-LSHLGSALFPD------------------------------------------------------VALMNHSCSPNVIVTYK-------------GTVAEVRAVQEINPEEEIFNSYIDLLYPTEDRIERLKDSYFFNCDCKECTSKSKDEAKMEIRQ-KLSIPPEEEEIKQMVIYARNVIEEFRRAKHYKTPSELLEICELSMEKMGAIFAETNVYMLHMMYQAMGVCLYMQDWDGAMKYGEKIIHPYSVHYPPYSLNVASMYLKLGRLYLGLEKRTQGVKALKKALAIMDIAHGKDHPYIDEIKKEMEEQT---------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5RGL7-1", "uniprot_id": "SMY2B_DANRE", "id": "Q5RGL7-1", "name": "N-lysine methyltransferase SMYD2-B", "aln": "MMKAEGIPGIEQFASPGK----GRGLRVSRAYGVGELLFSCPAYS-YVLSVGERGLICEQCFTRKKGLAKCGKCKKAFYCNANCQKKNWPMHKLECQAMCAFGENWRPSETVRLVARIIARLKAQKERSPSEILLLLGEMEAHLEDMDNEKREMTEAHIAGLHQFYSKHLD----FPDHQALLTLFSQVHCNGFTVEDEE-LSNLGLAIFPD------------------------------------------------------IALLNHSCSPNVIVTYR-------------GINAEVRAVKDISPGQEIYTSYIDLLYPTADRLERLRDMYYFSCDCKECTTKSMDVVKMSVR--KRSDEIGEKEIKDMVRYARNSMENFRRAKQDKSPTELLEMCELSIDKMSTVFDDSNVYILHMMYQAMGICLFTEDYEGAVRYGEKVIKPFTVLYPAYSMNVASMFLKLGRLYIALDRKLAGIDAFQKALTIMEVVHGKDHTYVTELKQEMRDF----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12529-1", "uniprot_id": "SET6_YEAST", "id": "Q12529-1", "name": "Potential protein lysine methyltransferase SET6", "aln": "MTIDGDVHEISPFFQVRQTKWGGRACFSNGNIPKGTTVLQVSNFTGTSISYEFRKEVCHNCFAYANAKTMKYKLNYDYLRDLVCNAHYQINPKKFLGAGLWFCSEHCRTSYLQIPN----------------IIELIECYEILLHHFPSMLKR---------YNYTSEQEE------------KLNSILISENVIQSSWD---EIESKWIPR---------------------------------------------------------INN--------------------------MKSAKRINQLPPTCEDEYCCIRFVCES------LFNLKYMDPQCITYRAFN----MLQSN-----------------ELSKISKFPVLLHFQKLVFQTLYILLPSHLHRMLS-IPLLRHILGTEYGNAFGLWQEGEASDSREYFGYWVFPEASYFNHSCNPNITKYRKGNSMLFTMNRDIKKDEQICIDYSGVLDLPTVKRRAFLADSWFFDCACERCKSELQSVH-----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : *.. . : : : *. *: : . . *: : . ::: : . : : : : . : .: . . : * :*: : : : * . :: : * . : * . : . . . : :. . . :: : :. : ", "identical_positions": 10, "similar_positions": 59, "identity": "1.79%" }, { "cls_id": "homologset.agr.SGD:S000006088", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61493-1", "uniprot_id": "REV3L_MOUSE", "id": "Q61493-1", "name": "DNA polymerase zeta catalytic subunit", "aln": "---------------------MFSVRIVTADYYMASPLPGLDTCQSPLTQLPVKKVPVVRVFGATPAGQKTCLHLHGIFPYLYVPYDGYGQQ---------------PESYLSQMAFSIDRALNVALGNPSSTAQHVFKVSLVSGMPFYGYHEKERHFMKIYLYNPAMVKRICELLQSGAIMNKCYQPHEAHIPYLLQLFIDYNLYGMNLINLAAVKFRKARRKGNASHATG--------LFKHQLSGNSPAGTLFR-WEEDEIPSSLLLEGVEPLSTCELEVDAVAADILNRLDIEAQIGG---NPGLQAIWEDEKQRRRNRNESSQISQPESQDCRFVPATESEKQFQKRLQEVLKQNDFSV-TLSGSVDYSNGSQEFSAELTLHSEILSPEMLPCSPANMIEVHKDTDL-SKGNTKHKVEEALINEEAILNLIENSQTFQPLTQRLSETPVFMGSSPDESLVHLLAGLESDGYQGEKNRMPLPCHSFGESQNPQNSDDEENEPQIEKEEMELSVVMSQRWDSDIEEHCAKKRSLCRNAHRSSTEEDDSSSEEEMEWTDNSLLFANLSIPQLDGTADENSDNPLNNENSRAHSSVIATSKLSVRPSIFHKDAATLEPPSSAKITFQCKHTSALSSHVLNKDGLTEDLSQPNS-TEKGRDNSVT-FTKESTYSMKYSGSLSSTVHSDNSHKEICKKDKSLPVSSCESSVFDYEEDIPSVTRQVPSRKYSNMRKIEKDASCIHVNRHISETILGKNSFNFADLNHSKRKLSSEGNEKGNSTSLSGVFPSSLTENCDLLPSSGENRSMAHSLESITDESGLNKLKIRYEEFQEHKMEKPSLSQQAAHYMFFPSVVLSNCLTRPQKLSP------VTYKLQ-SGNKPSRLKLNKKKLIGLQETSTKSTETGATKDSCTHNDLYTGASEKENGLSSDSAKATHGTFENKPPTEHFIDCHFGDGSLEAEQSFGLYGNKYTLRAKRKVNYETEDSESSFVTQNSKISLPHPMEIGENLDGTLKSRKRRKMSKKLPPVIIKYIIINRFRGRKNMLVKLGKIDSKEKQVILTEEKMELYKKLAPLKDFWPKVPDSPATKYPIYPLTPKKSHRRKSKHKSAKKKPGKQHRTNSENIKRTLSFRKKRTHA---VLSPPSPSYIAETEDCDLSYSDVMSKLGFLSERSTSPINSSPPRCWSPTDPRAEEIMAAAEKESMLFKGPNVYNTKTVSPRVGKASRARAQVKKSKARLANSSVVTNKRNKRNQTTKLVDDGKKKPRAKQKQRANEKSLSRKHAIPADEKMKPHS--EAELTPNHQSVSELTSSSG-AQALSKQKEMSQTGPAVDHPLPPAQPTGISAQQRLSNCFSSFLESKKSVDLRTFPSSRDDSHSSVVYSSIGPGISKINIQRSHNQSAMFTRKETTLIQKSIFDLSNHLSQVAQSTQVCSGIISPKTEESSSTQKNCGSSMGKLNEYRSSLESKPEQVCAPNFLHCKDSQQQTVSVSEQSKTSETCSPGNAASEESQTPN-CFVTSLKSPIKQIAWEQKQRGFILDMSNFKPEKVKQRSLSEAISQTKALSQCKNQNVSTPSVFGEGQSGLAVLKELLQKRQQKAQSTNVVQDSTS-THQPDKNISVSNEHKKANKRTRPVTSPRKPRTPRRTKPKEQTPRRLKVDPLNLQTSGHLDNSLSDDSPILFSDPGFESCYSLEDSLSPEH--NYNFDINTIGQTGFCSFYSGSQFVPADQNLPQKFLSDAVQDLFPGQAIDKSELLSHDRQSCSEEKHHVSDSSPWIRASTLNPELFEKVAMDNNENHRHSQWKNSFHPLTSHSNSIMESFCVQQAENCLTEKSRLNRSSVSKEVFLSLPQANSSDWIQGHNRKEADQSLHSANTSFTTILSSPDGELVDAASEDLELYVSRNNDVLTPTPDSSPRSTSSPLQSKNGSFTPRTAHILKPLMSPPSREEIVATLLDHDLSEAIYQEPFCSNPSDVPEKPREIGGRLLMVETRLPNDLIEFEGDFSLEGLRLWKTAFSAMTQNPRPGSPLRNGQAVVNKESSNSHKMVEDKKIVIMPCKYAPSRQLVQAWLQAKEEYERSKK----LPKTELTPVTKSAENVSPSLNPGDTCAVSPQVDKCPHTLSSSAHTKEEVSKSQIALQTSTTGC------SQTLLAAASAAVPEEDEDD---------NDNCYVSYSSPDSPGIPPWQQAASPDFRSLNGDDRHSSPGKELCSLAVENFLKPIKDGIQKSSCSESWEPQVISPIHARARTGKWDPLCLHSTPVMQRKFLEKLPEATG-LSPLSVEPKTQKLYNKKGSDADGLRRVLLTTQVENQFAAVNTPKKETSQ-IDGPSLNNTYGFKVSIQNLQEAKALHEIQNLTLISVELHARTRRDLQPDPEFDPICALFYCISSDTPLPDTEKTELTGVIVIDKDKTVTHQDIRSQTPLLIRSGITGLEVTYAADEKALFQEITNIIKRYDPDILLGYEIQMHSWGYLLQRAAALS-VDLCQMISRVPDDKIENRFAAERDDYGSDTMSEINIVGRITLNLWRIMRNEVALTNYTFENVSFHVLHQRFPLFTFRVLS-DWFDNKTDLYRWKMVDHYVSRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRGSQYRVESMMLRIAKPMNYIPVTPSIQQRSQMRAPQCVPLIMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTCLGHVENLGKYDEFKFGCTSLRVPPDLLYQIRHD--VTVSPNGVAFVKPSVRKGVLPRMLEEILKTRLMVKQSMKSYKQD-RALSRMLNARQLGLKLIANVTFGYTAANFSGRMPCIEVGDSIVHKARETLERAIKLVNDTKKWGARVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNPRPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKEPVFDAKGIETVRRDSCPAVSKILERSLKLLFETRDISLIKQYVQRQCMKLVEGKASIQDFIFAKEYRGSFSYRPGACVPALELTRKMLAYDRRSEPRVGERVPYVIIYGTPGLPLIQLIRRPAEVLQDPTLRLNATYYITKQILPPLARIFSLIGIDVFSWYQELPRIQKA-----TSSSRSELEGRKGTISQYFTTLHCPV-CDDLTQHGICSKCRSQPQHVAIILNQEIRELERKQEQLIKICRNCTG---------SFDRHIPCVSLNCPVLFKLSRVNRELSKAPYLRQLLDQF-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M8G6-1", "uniprot_id": "F1M8G6_RAT", "id": "F1M8G6-1", "name": "DNA polymerase zeta catalytic subunit", "aln": "---------------------MFSVRIVTADYYMASPLPGLDICQSPLTQHPVKKVPVVRVFGATPAGQKTCLHLHGVFPYLYVPYDGYGQQ---------------PERYLSQMALSIDRALNVALGNPSSTAQHVFKVSLVSGMPFYGYHEKERHFMKIYLYNPAMVKRICELLQSGAIMNKFYQPHEAHIPYLLQLFIDYNLYGMNLINLAAVKFRKARRKGDASHATG--------LFKPQLSGNSPAGTLFR-WEEDEIPSSLLLEGVEPLSTCELEVDAVAADILNRLDIEAQIGG---NPGLQAIWEDEKQRRRNRNENSQISQPESQDCRLVPATESEKIFQKRLQEILKQNDFSVRTLSGSVDYSSGSQEFSAELTLHSEILSPEMLPCSPANMIEVHRDNDW-SKGNTKHKVEEALINEEAILNLIENSQTFQPLTQRLSETPVFMDSSPDESLVHLLAGLESDGYQGEKNRMPLPRHTFGESQNPQNSDDEENAPQMEKEEMELSVLMSQRWDSDTEEQCAKKRSLCRNAHRSSTEEDDSSSEEEMEWTDNSLLFANLSIPQLDGTADENSDNPLNNENSRAHSSVIATSKLSVRPSVFHKDAATLEPPSSAKITFQCKHTSALSSHGLNKDDLIEGLSQPNN-TEKGRDSSVT-FTKESTYSMKYSGSLSSTVHSDNSHKEICKKDKSLPVPSCESSVFDYEEDIPSVTRQAPSRKYSNMRKIEKDAPFIHANRHTSESTLGKNSFNFADLNHSKNKLSSEGNERGNSTALNSVFPSSLAESCDLLSSSGENRSVAHSLDSITDESGRSKLKIRYEEFQEHKMERPSLSQQAAHYMFFPSVVLSNCLTRPQKLSP------VTYKLQ-PGSKTSRLKLNKKKLISLQETSTKSSETGAAKDSCTHNHPYSGTPEKESGLSSDLIKATHGTFENKTPTEHFIDCHFGDGSLETEQSFGLYGNKYTLRAKRKVNYETEDSESSFVTHNSKISLPHPMEIGENLDGTLKSRKRRKMSKKLPPVIIKYIIINRFRGRKNMLVKLGKIDSKEKQVILTEEKMELYKKLAPLKDFWPKVPDSPATKYPIYPLTPKKSHRRKSKHKSAKRKPGKQHRASSENIKRTLSFRKKRTHA---VLSPPSPSYIAETEDCDLNYSDVMSKLGFLSERSTSPVNSSPPRCWSPTDPRAEEIMAAAEKESVLFKGPNVCNTKTVSPRVGKASRARAQVKKSKARLAKSSVVTNKRNKRNQTNQLVDNGKKKPRAKQKQRANEKGISRKPVIPTDETTKPPS--EAELTPSQRSVPELTSSSG-IHTLSKQKEMTQTGPAMDHPLPPCQPTGINAQQRLSNCFSSFLESRKSVQFPTFPSSRGDSRSS-VYSSIGPGVSKVNTQRSHSQSAMFTRKETTLIQKSIFDLSNHLSQVAQSTQLCSGIISPKTEESSNTQKNCGSSIGKLNEYRSSLESKPEKVCAPNFLHCRDSQQQTVNVSEQSKPSETCSPGNAASEESQTPN-CFVTSLRSPIKQITWEQRQRGCILEMSSFKPEKVKQRSLSEAISQTKALSQCKNQNVSTPSVFGEGQSGLAVLKELLQKRQQKAQTTN-VQDSAS-SHQPDKDISVSAEHKKTNKRTRAVASPRKPRAPRRTKPKEQTPRRLKVDPLNLQTSGHLDNSLSDDSPILFSDPGFESCYSLEDSLSPEH--NYNFDINTIGQTGFCSLYSGSQFVPADQNLPQKFLSDAVQDLFPGQAIEKNELLSHDRQSCTEEKHHVSDSGPWVRASTLNPELFEKVGIDNNENHRHSQWKTSFHPLTSHSNSIMESFCVQQAESCLPEKSRLNRSSVSKEVFLSLPQASSSDWIQGHNGKEIEQSLDSANTSFTTVLSSPDGELVDAASEDLELYVSRNNDVLTPTPDSSPRSTSSPLQSKNGSFTPRTAHILKPLMSPPSREEIVATLLDHDLSEAIYQEPFCSNPSDVPEKPREIGGRLLMVETRLPNDLIEFEGDFSLEGLRLWKTAFSAMTQNPRPGSPLRNGPAVVNKESSNSHKTVEDKKIVIMPCRYAPSRQLVQAWLQAKEEYVRSKR----LPRTESTPVIKSADNVSPSLNPGDTRAVAPQMDTCPHTLSSTAHAKEEVCQSQIALQTSRTGCGQTVSASQTLLPAASAAVPEEEEEEEEEEEEEEEDENGYVSYSSPDSPGIPPWQQAASPDFRALNGEHRCSSPVEELCSRAVENFLKPIKDGIQKASCCES---QVISPIHARTRTEKCEPLCLHSTPVMPRKFLEKLPEATG-LSPLSVEPKTQKLYNKKGSDTDHLRRVLLTTQVENQFAAVNTPKKETSQ-IDGPSLNNTYGFKVSIQNLQEAKALHEIQNLTLISVELHARTRRDLQPDPEFDPICALFYCISSDTPLPDTEKTELTGVIVIDKDKTVTHQDIRCQTPLLIRSGVTGLEVTYAADEKALFQEVTNIMKRYDPDILLGYEIQMHSWGYLLQRAAALS-VDLCQMISRVPDDKIENRFAAERDDYGSDTMSEINIVGRITLNLWRIMRNEVALTNYTFENVSFHVLHQRFPLFTFRVLS-DWFDNKTDLYRWKMVDHYVSRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRGSQYRVESMMLRIAKPMNYIPVTPSVQQRSQMRAPQCVPLIMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTCLGHIENLGKYDEFKFGCTSLRVPPDLLYQIRHD--ITVSPNGVAFVKPSVRKGVLPRMLEEILKTRFMVKQSMKAYRQD-RALSRMLNARQLGLKLIANVTFGYTSANFSGRMPCIEVGDSIVHKARETLERAIKLVNDTKKWGARVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNPKPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKDPVFDAKGIETVRRDSCPAVSKILERSLKLLFETRDISLIKQYVQRQCMKLVEGKASIQDFIFAKEYRGSFSYRPGACVPALELTRKMLAYDRRSEPRVGERVPYVIVYGTPGLPLIQLIRRPAEVLQDPTLRLNATYYITKQILPPLARIFSLIGIDVFSWYQELPRIQKA-----TSSSRSDLEGRKGTISQYFTTLHCPV-CDGLTQHGICSQCRSQPQHVAIILNQEIRELERQQEQLVKICRNCTG---------SFDRHIPCVSLNCPVLFKLSRVNRELSKAPYLRQLLDQF-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60673-1", "uniprot_id": "REV3L_HUMAN", "id": "O60673-1", "name": "DNA polymerase zeta catalytic subunit", "aln": "---------------------MFSVRIVTADYYMASPLQGLDTCQSPLTQAPVKKVPVVRVFGATPAGQKTCLHLHGIFPYLYVPYDGYGQQ---------------PESYLSQMAFSIDRALNVALGNPSSTAQHVFKVSLVSGMPFYGYHEKERHFMKIYLYNPTMVKRICELLQSGAIMNKFYQPHEAHIPYLLQLFIDYNLYGMNLINLAAVKFRKARRKSNTLHATG--------SCKNHLSGNSLADTLFR-WEQDEIPSSLILEGVEPQSTCELEVDAVAADILNRLDIEAQIGG---NPGLQAIWEDEKQRRRNRNETSQMSQPESQDHRFVPATESEKKFQKRLQEILKQNDFSV-TLSGSVDYSDGSQEFSAELTLHSEVLSPEMLQCTPANMVEVHKDKES-SKGHTRHKVEEALINEEAILNLMENSQTFQPLTQRLSESPVFMDSSPDEALVHLLAGLESDGYRGERNRMPSPCRSFGNNKYPQNSDDEENEPQIEKEEMELSLVMSQRWDSNIEEHCAKKRSLCRNTHRSSTEDDDSSSGEEMEWSDNSLLLASLSIPQLDGTADENSDNPLNNENSRTHSSVIATSKLSVKPSIFHKDAATLEPSSSAKITFQCKHTSALSSHVLNKEDLIEDLSQTNKNTEKGLDNSVTSFTNESTYSMKYPGSLSSTVHSENSHKENSKKE-ILPVSSCESSIFDYEEDIPSVTRQVPSRKYTNIRKIEKDSPFIHMHRHPNENTLGKNSFNFSDLNHSKNKVSSEGNEKGNSTALSSLFPSSFTENCELLSCSGENRTMVHSLNSTADESGLNKLKIRYEEFQEHKTEKPSLSQQAAHYMFFPSVVLSNCLTRPQKLSP------VTYKLQ-PGNKPSRLKLNKRKLAGHQETSTKSSETGSTKDNFIQNNPCNSNPEKDNALASDLTKTTRGAFENKTPTDGFIDCHFGDGTLETEQSFGLYGNKYTLRAKRKVNYETEDSESSFVTHNSKISLPHPMEIGESLDGTLKSRKRRKMSKKLPPVIIKYIIINRFRGRKNMLVKLGKIDSKEKQVILTEEKMELYKKLAPLKDFWPKVPDSPATKYPIYPLTPKKSHRRKSKHKSAKKKTGKQQRTNNENIKRTLSFRKKRSHA---ILSPPSPSYNAETEDCDLNYSDVMSKLGFLSERSTSPINSSPPRCWSPTDPRAEEIMAAAEKEAMLFKGPNVY-KKTVNSRIGKTSRARAQIKKSKAKLANPSIVTKKRNKRNQTNKLVDDGKKKPRAKQKT--NEKGTSRKHTTLKDEKIKSQSGAEVKFVLKHQNVSEFASSSGGSQLLFKQKDMPLMGSAVDHPLSASLPTGINAQQKLSGCFSSFLESKKSVDLQTFPSSRDDLHPSVVCNSIGPGVSKINVQRPHNQSAMFTLKESTLIQKNIFDLSNHLSQVAQNTQISSGMSSKIEDNANNIQRNYLSSIGKLSEYRNSLESKLDQAYTPNFLHCKDSQQQIVCIAEQSKHSETCSPGNTASEESQMPNNCFVTSLRSPIKQIAWEQKQRGFILDMSNFKPERVKPRSLSEAISQTKALSQCKNRNVSTPSAFGEGQSGLAVLKELLQKRQQKAQNANTTQDPLSNKHQPNKNISGSLEHNKANKRTRSVTSPRKPRTPRSTKQKEKIPKLLKVDSLNLQNSSQLDNSVSDDSPIFFSDPGFESCYSLEDSLSPEH--NYNFDINTIGQTGFCSFYSGSQFVPADQNLPQKFLSDAVQDLFPGQAIEKNEFLSHDNQKCDEDKHHTTDSASWIRSGTLSPEIFEKSTIDSNENRRHNQWKNSFHPLTTRSNSIMDSFCVQQAEDCLSEKSRLNRSSVSKEVFLSLPQPNNSDWIQGHTRKEMGQSLDSANTSFTAILSSPDGELVDVACEDLELYVSRNNDMLTPTPDSSPRSTSSPSQSKNGSFTPRTANILKPLMSPPSREEIMATLLDHDLSETIYQEPFCSNPSDVPEKPREIGGRLLMVETRLANDLAEFEGDFSLEGLRLWKTAFSAMTQNPRPGSPLRSGQGVVNKGSSNSPKMVEDKKIVIMPCKCAPSRQLVQVWLQAKEEYERSKK----LPKTKPTGVVKSAENFSSSVNPDDKPVVPPKMDVSPCILPTTAHTKEDVDNSQIALQAPTTGCSQTASESQMLPPVASASDPEKDEDD---------DDNYYISYSSPDSPVIPPWQQPISPDSKALNGDDRPSSPVEELPSLAFENFLKPIKDGIQKSPCSEPQEPLVISPINTRARTGKCESLCFHSTPIIQRKLLERLPEAPG-LSPLSTEPKTQKLSNKKGSNTDTLRRVLLT-QAKNQFAAVNTPQKETSQ-IDGPSLNNTYGFKVSIQNLQEAKALHEIQNLTLISVELHARTRRDLEPDPEFDPICALFYCISSDTPLPDTEKTELTGVIVIDKDKTVFSQDIRYQTPLLIRSGITGLEVTYAADEKALFHEIANIIKRYDPDILLGYEIQMHSWGYLLQRAAALS-IDLCRMISRVPDDKIENRFAAERDEYGSYTMSEINIVGRITLNLWRIMRNEVALTNYTFENVSFHVLHQRFPLFTFRVLS-DWFDNKTDLYRWKMVDHYVSRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRGSQYRVESMMLRIAKPMNYIPVTPSVQQRSQMRAPQCVPLIMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTCLGHVENLGKYDEFKFGCTSLRVPPDLLYQVRHD--ITVSPNGVAFVKPSVRKGVLPRMLEEILKTRFMVKQSMKAYKQD-RALSRMLDARQLGLKLIANVTFGYTSANFSGRMPCIEVGDSIVHKARETLERAIKLVNDTKKWGARVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNPKPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKDPVFDAKGIETVRRDSCPAVSKILERSLKLLFETRDISLIKQYVQRQCMKLLEGKASIQDFIFAKEYRGSFSYKPGACVPALELTRKMLTYDRRSEPQVGERVPYVIIYGTPGVPLIQLVRRPVEVLQDPTLRLNATYYITKQILPPLARIFSLIGIDVFSWYHELPRIHKA-----TSSSRSEPEGRKGTISQYFTTLHCPV-CDDLTQHGICSKCRSQPQHVAVILNQEIRELERQQEQLVKICKNCTG---------CFDRHIPCVSLNCPVLFKLSRVNRELSKAPYLRQLLDQF-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T757-1", "uniprot_id": "A0AB32T757_DANRE", "id": "A0AB32T757-1", "name": "DNA polymerase zeta catalytic subunit", "aln": "----------MSCSVWFCRINMFSVRIVTADYYMSSPIRELDVCYSEFRESDVKKVPVVRIFGATPAGQKTCLHLHGIFPYIYVPYDGFGQE---------------ADRYLRQVAYSIDRALNISMGNPSSNVQHIFKVVLVTGMPFYGYHMREKSFMKIFLYNPQMVKRVSELLQAGAVMNKSFQPHEAHIPFLLQLFIDYNLYGMNMISLAAVKFRKSRATASEEEQMGGGTSPLRNACASTFNETGLRDTLCTRWEENNIPSSLILEEVERVSVCELEVDAVAADVLNRLEIENQIGR---NPGLQAIWDDEKQRRRQRSESSHIDVTESQDRDLAEVAESEKIFMKRVKDILRENEFDMTQAGSEMDS-------FPDLSLYSTVLSPDRLPSIHASQVDLHQDAVKDTKRDSRKDDEVAVVDEEAILSMLENSQSFLQLSQTSSQSAIFDGSQ-EQAMVDLLEALANDGF-GDKSSKAVTQQLTGIASCVYNSDDEEAGPELEKKESELSKIMSQRWDSDIPEPSARQR-LFMKANESSSEEQQASSDEEGNWKGINSFQTDLSIPQLDGAADESSDSSLKEKGSQRRSYITGTDKILASRKVFANEAVRIEASSSVNIVNEYKCSEQRP----DREDLADKHSKCGESIESSNISSLK-EVTPVKHPISSNSRITYKVDSDH--------------PDLEDLMFGNSKLAQSIK------KYSSIKHVEKNTLLILEDQRSS-------SACYSGLTDSATKTKIVLNPSDCRS------PVKVFDQTQTLEDSPALGPEESEMGQGTKEDDVGELKIRYEDYQENKADRTIVAQQEAHYKFFPSVILSNCLARPIKKQAGSKIGEVSCTLDQPEQRKSRLKLTKKKPTLDQKRELPVKTHSPTKEEPPALLSITPGSHNQNEVSKEVDMETSGSLIESSGKGDFADIPTN---ISCTKVASLPGSKYTLRTKRKRIYEKGDHPRSGSSKQASVHHDDPKGS-----DHVFSQKKRKVTKKEPPVIIKYIIINRFKGQKNMLVKISKVSSDETHTVLTPEKLAGYEQLAPLKKFWPKIPESTAEKYPSLEPKVKKCPKRKAKINPVVKRMTTFPKSKCPRVGQTRGERRAKAMLPVQTLAPPWPSYNDFTDDTCTEYCDVMMKLGYLSERAPSPTDSTPPRCWSPT----EHLHGSNSNDHFINPHNDPCLGSSCEALTPKPSQSGLLNRSRMQRPKKTSGTSQKRKSNSLTTATNKGSLKTEDSKWKS---IPAASRKHKKYCDG-------------IERPMFVDVTSTSQ-KGWMRNEKQLLQR--KQDHGKGSNNSQGLNSSDNLP--VTQLSDYLTPFQCPSFLKSNPEDLALGCSDSKTEVHSFFDSIASNNSQKDLRIAPNSTIEKSFSILS----QPTKTVGHPCSVITYGSSNSKSKNTSQDGTKTKNHDVISVVSGHEERSGT-----VQQSQLPITSRRPQARKKDTG------------------TALLKPVDSISSPTSS--------------TKSAAIYESNTDLTLSSDFKNR-------------EMCVLKELLQKRQLKEEQEANKSDGLT---EAVSSTSQNTDVAKRAKSKRTLSSP--SRKPRGARTKVQTRCKK-----NKQDDQRNDCLSSDGSPVFFSDPGFDSCCSVEDSLSPELPDNYRFDINVIGQTEFSSLYSGNQFVLTDKILPQKFLSDVSQEAAN--ALVGLGNRTQKMFDVDDDFNHGNDRN---KSGALSPELFDKVSCE---NGRVFPNKVSLSLLDSEK---IFSTNWAGSLGKIHGLSHFRDFHCEKRDVLLDPEPKSP--------------IMSASFAYG---VSPNSDLLDGS---------------SLTPSSSPRSINSLSQLKTS--RTGGTRILKPLMSPPAREEILANLMDLDFSEATKQEPFYSDPSDVPLKPREVGGRKLILETRQASRLVEFHGDLSQNGLQFWKVAFSAMTNQASAPTQGCKSSKLIKNQSPSS---VSDPKVIILPCKCAPSREQVQLWAQAKKQYECLQRGRIQMGGHEISELKQSTCDRSTTQKTSN-SLFSENHDKRPEKNSESQHNSRNDFCSPIHFSPVKAAS------SDSSPSSVKCVQDIDKTKD-------------CRITSPPNSPEISTWQD--SPD--EVEQDEDKENLTGGLQPLSMDQNLN---ETLLENAESKDHLSPSFFGIKGLVSDVRCS-HLLHSTPVQRRNSTDDEASSCSPVRHEDTECRSQRLHQRSNKNKNALRRVLLSTQVKNQLINMNVPKKENSQ-IEGPSFCNSYGFKVSMQNLQEAKALHEVQHLTLMSMELHARTRRNLEPDPEFDPICALFYCLSSDVLLHDSGTTRIEGAIVIDKESCTSAQASRSSTPFLFRCGVTGLPVTYTCDEKELFEEVSNIIRKYDPDILVGYEVQMHSWGYLLQRASTLG-VNLCQQLSRVPGDSQQNHFIPEKDEYGAETMTEIHITGRIILNIWRIMKTEAALNNYTFENVAFHLLHQRYPLYSHRTLS-DWFD--THLHRWKVMDHYVSRVCGTVQLLQQQDIIGRTSELARVFGIQFYHVLTRGSQYRVESMMLRVAKPMNYIPVTPSTQQRAQQRAAQCIPLVMEPESRFYSNSVIVLDFQSLYPSIVIAYNYCYSTCLGHIENLGTYDEFKFGCASLRVPPDLLYQLRND--ITVSPNGVAFVKSSVRRGVLPRMLEEILKTRIMVKQSMKAYRND-KALSRLLDARQLGLKLIANVTFGYTSANFSGRMPCVEVGDSIVHKARETLERAIKMVNDTKKWGARVVYGDTDSMFVLLKGATKEQAFKIGNEIAEAVTATNPKPIKLKFEKVYLPCILQTKKRYVGYMYESVDQENPVFDAKGIETVRRDGCPGVSKILERSLKLLFESRDISQVKQYVQRQCVKVVEGKASMQDLTFAKEYRGSGSYRPGACVPALELTRRMMAFDRRLEPRVGERVPYVIVYGSPGVPLIQLVRRPLEVLQDPSLRLNATYYITKQILPPLARIFNLIGVDVFSWYHELPRVQRAW--SFTSSGRGEEGTKKGTISQYFTTLHCPV-CDELTQLGVCARCRAEPQCVAVHLHQDLRLWESQQDQLLKICRSCSG---------SAERQVPCVSLDCPILYKLSRVNRNLSRGPYLRQLVEQFL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9GSR1-1", "uniprot_id": "DPOZ_DROME", "id": "Q9GSR1-1", "name": "DNA polymerase zeta catalytic subunit", "aln": "-----------MAAAGEAIDGVYSVRLVIADFYMEKPQFGMDPCYSELRGKEIKRVPVIRVFGGNSRGQKTCMHVHGVFPYLYIPYDKKDFES--------------LERGILQMAMHLDKAINISLGQGSSNAQHVFKIQLVKGIPFYGYHRVEHQFLKIYMFNPRFVRRAANLLQSGAILSKNFSPHESHVPYILQFMIDYNLYGMSYVHVPLEVLKFRRNHDDDVIPYAN----------------------------VKQAQLLDITTAKKVACSALEVDVSSNFILNRFQLVAKSKSNHTNPGIEAIWNDEKLRR-QKLVEKHTDAGDEEKAEAVPVLELPPTQERHQIEIAESDIFYRTALES------------KLMTLEQSTLSEQTLSDQTILPQATMQTTMPGTKAQKRRFNLQKLLANAVYPEECSQDQQQLLVNASFIQNHVTCGYS-----------------------------------------------------SSVSLSTSKDESDDLDETVVDEELILSLTQPHGAIPHDATLREE-----------DLELLDALQLLEEQNESESHVDLDSSLAPLSQHKKFELTPELLDKETAATAALFDEDVD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDEDADQETRHDFSTVLDDVDELLLKLTQSQPAESKELKASSKLPQIDGADDRLQRTPIKSISSKSK---------------SSPSKTPTTPIGQKSLPKSPRTPKTSAAKKYAPLALTIGSSSSKKSNDEFAGRPSNPRLSLQLDQGTG-----------------------------TGTLRPEISLRKKLAMSEMRRKSFEDSFVLLKNDCTPVRSTRRSTSNLDKTHIICSLTPRDRNPGLSDMFETEDGKQLPPKKVVRKTRWSTRNQDIESLPKAGCEIERPHRSEGSALDELKPRRSARHKVNSANPDECSSEIQTTGPRVTTTSLDRPQKKAR--------------------------------------------------------------------LSQSPKENTKTSMNGTVALEKATKDSSSNSESPHQQENSVSEQIEYLESKPKKSDETARSCDEKLQR----------------------------------------------------------------ELIPQEPAGISPG-----------DSANSTEEITFSPCHDEAIESDTESD-----YIVTKLRKTPNLKRLRWSIRSELLN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KQFTPSSGIRPPETETTPQLSPKSNES-------------------------------------------------------------------------------------------------------------------------------------------------------------------------NTPELMRSFYEHSLIVNSPSVFSDFLDSPEIHMD------------------------------------------------------SPRSAPPSPDS------------NSFVIAPLELPPSYDEVVSGSRKMDIPEYEFQKPYYSNPSDVS-KVTEVGFLVLHIPGNKLNDCDPFQSILGND------RGLASWRRRQLIAIGGLAMLQRHRGEQKVREYFSTQQRIAIEPAQLAPTWQEAKIWLKAKELLRQREE------------PKKSSDDIDSPIKIKRQKITMMLQAEEGDGGSGDEDAGEELDCS---------------------------------------------------------------------------------------------------------------------LSLTPLSQAKDKCKATPTSSKARETGKSRLKRGTRLSFIGSQDEEPPSSQSSEQSVSSSAAQAELDRSSFLRQLEGSSQDRQHDLSFGLSHATLDNTFGFKVNLENLQQAKADIDCNHLTIITLEVFVSTRGDLQPDPMHDEIRCLFYAIEHSLPDEKLPSKACGYIMVNTVQDLLSEGP--------FHGIDRDIEVQVVTSEAEAFEALLALCERWDADIYAGYEIEMSSWGYVIDRAKHLC-FNIAPLLSRVPTQKVR-DFVDEDREQFTDLDVEMKLCGRILLDVWRLMRSEIALTSYTFENVMYHILHKRCPWHTAKSLT-EWFG--SPCTRWIVMEYYLERVRGTLTLLDQLDLLGRTSEMAKLIGIQFYEVLSRGSQFRVESMMLRIAKPKNLVPLSPSVQARAHMRAPEYLALIMEPQSRFYADPLIVLDFQSLYPSMIIAYNYCFSTCLGRVEHLGGSSPFEFGASQLRVSRQMLQKLLEHDLVTVSPCGVVFVKREVREGILPRMLTEILDTRQMVKQSMKLHKDS-SALQRILHSRQLGLKLMANVTYGYTAANFSGRMPSVEVGDSVVSKGRETLERAIKLVENNEEWKVRVVYGDTDSMFVLVPGRNRAEAFRIGEEIAKAVTEMNPQPVKLKLEKVYQPCMLQTKKRYVGYMYETADQEQPVYEAKGIETVRRDGCPAVAKMLEKVLRILFETQDVSKIKAYVCRQFTKLLSGRANLQDLIFAKEFRGLNGYKPTACVPALELTRKWMQKDPRHVPRRGERVPFIIVNGPPGMQLIRLVRSPHDILANEGHKINAIYYITKAIIPPLNRCLLLIGANVHDWFASLPRKLLMTPAVGTANELAGARGAKSTISQYFSTTSCVIDCGRQTKAGICPDCLKNATTCVVVLSDKTARLERGYQLTRQICQACCG---------RLG-SLQCDSLDCPVLYVLEGKRRELQQIEHWNKLLEHHF----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14284-1", "uniprot_id": "DPOZ_YEAST", "id": "P14284-1", "name": "DNA polymerase zeta catalytic subunit", "aln": "MSRESNDTIQSDTVRSSSKSDYFRIQLNNQDYYMSKPTFLDPSHGESLPLNQFSQVPNIRVFGALPTGHQVLCHVHGILPYMFIKYDGQITDTSTLRHQRCAQVHKTLEVKIRASFKRKKDDKHDLAGDKLGNLNFVADVSVVKGIPFYGYHVGWNLFYKISLLNPSCLSRISELIRDGKIFGKKFEIYESHIPYLLQWTADFNLFGCSWINVDRCYFRSPVLN-----------------------------------------SILDIDKLTINDDLQLLLDRFCDFKCNVLSRRDFPRVG------------------------------------------------------------------------------------------------------------------------NGLIEIDILPQFIKNREK----------------------------------------------------------------------------LQHRDIHHDFLEKLGDISDIPVKPYVSSAR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DMINELTMQREELSLKEYKEPPETKRHVSGHQWQSSGEFEAFYKKAQHKT------------------STFDGQIPNFENFIDKNQKFSAINTPYEALPQLWPRLPQIEINNNSMQD--------------------------------------------------------------------------------------------KKNDDQVNASFTEYEICGVDNENEGVKGSNIKSRSYSWLPESIASPKDSTILLDHQTKYHN--TINFSMDCAMTQNMASKRKLRSSVSANKTSLLSRKRKKVMAAGLRYGKRAFVYG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EPPFGYQDILNKLEDEGFPKIDYKDPFFSNPVDLENKPYAYAG-----------------------------KRFEISSTHVSTRIPVQFGGETVSVYNKPTFDMFSSWKYALKPPTYDAVQK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WYNKVPSMGNKKTESQISMHTPHSKFLYKFASDVSGKQKRKKSSVHDSLTHLTLEIHANTRSDKIPDPAIDEVSMIIWCLEEETFPLDLDIAYEGIMIVHKASEDS-------TFPTKIQHCINEIPVMFYESEFEMFEALTDLVLLLDPDILSGFEIHNFSWGYIIERCQKIHQFDIVRELARVKCQIKT----KLSDTWGYAHSSGIMITGRHMINIWRALRSDVNLTQYTIESAAFNILHKRLPHFSFESLTNMWNAKKSTTELKTVLNYWLSRAQINIQLLRKQDYIARNIEQARLIGIDFHSVYYRGSQFKVESFLIRICKSESFILLSPGKKDVRKQKALECVPLVMEPESAFYKSPLIVLDFQSLYPSIMIGYNYCYSTMIGRVREIN-LTENNLGVSKFSLPRNILALLKND--VTIAPNGVVYAKTSVRKSTLSKMLTDILDVRVMIKKTMNEIGDDNTTLKRLLNNKQLALKLLANVTYGYTSASFSGRMPCSDLADSIVQTGRETLEKAIDIIEKDETWNAKVVYGDTDSLFVYLPGKTAIEAFSIGHAMAERVTQNNPKPIFLKFEKVYHPSILISKKRYVGFSYESPSQTLPIFDAKGIETVRRDGIPAQQKIIEKCIRLLFQTKDLSKIKKYLQNEFFKIQIGKVSAQDFCFAKEVKLGAYKSEKTAPAGAVVVKRRINEDHRAEPQYKERIPYLVVKGKQGQLLRERCVSPEEFLEGENLELDSEYYINKILIPPLDRLFNLIGINVGNWAQEIVKSKRAS-------TTTTKVENITRVGTSATCCNCGEELTKICSLQLCDDCLEKRSTTTLSFLIKKLKRQKEYQTLKTVCRTCSYRYTSDAGIENDHIASKCNSYDCPVFYSRVKAERYLRDNQSVQREEALISLNDW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::: *:** .* . : ..:** :*:**. . *::. *:**::**::: ** : : : . : *: .. :.: .: :*.*:****** . * ** : ** : * .:*:: * ::.* :. :*:*:*::** *:**:* . : : :: . * : * :* . * :. :: . .: : : : * : . .: . .:* :: : . : .. :.: . : . . * . . . . .. . : . * .: . . :. * . : : . . :: .. . . . .: : : * . :::: . .:.: :.*: *:* *: * . : . . . : : * . : : : : . : . : * .:.. *: * : ** :::*:.. ** : *** * : :::.:. . . :* .. :: : * .* *. : : *.** *:*:. ****:::*. : .:: ::** : : : ** :::** ::.: *..**:*.. :::**:* * .: . *: * : ::::::.*. .: :* : * :.:. * *:::**:* * ****::***:::*:.*. . : ::*. : : :* : :.*:***:* ** ..::**********::*.****:** :*::..:. ::* :.: :. ::* : .. :*::* **.:.* .**.. *.:** :**..* *:*::*: :. :*.*:*. :**.***:****:***:*.******. ::.**:* ..*****:**.:::. : * .:********:** : * . ::* **. :*: ** **:*: **:**** *.:* :******: **: .* *:::**********. *. *::*: :::**:::*:* :* *: .: *: *:.. **: **** : :. .. :.:: : * * *: **:*:::: * * * . * :.* . .::: ***.* ::*** * : *** :* .* .: : :. : * . :* * : .: : . : : :*: * * * :**::: .* * .: ", "identical_positions": 298, "similar_positions": 440, "identity": "9.21%" }, { "cls_id": "homologset.agr.SGD:S000006090", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M355-1", "uniprot_id": "F1M355_RAT", "id": "F1M355-1", "name": "Tip-associated protein", "aln": "---------------------------------------------MESRSET----NPFRRRMRCRRIFRRRFLNSTEYISDTMRTSFYHQQDEELAMSNAPMYTR------RRYTPYGILSHHQRINLHKWDQMNVNMEEGAKPPERKME--------RDKQDDTSENWFKVTIPFGIKYDKKWMLNLIQSQCS-IPFTPVQFHYEKMQATFFVDDPNIAFMLKAISDKIRDETDNKPQSHITPS---------------VILQLTMN------QQCDTSQRILNRQRLSFDQDLTTYPTDLVLSPRRYMTPSLNISEEDVTQAN------------------------------------SEGKMAKEQASDIEEICAVKSSLSTTMPDKSSNINSILELFPKLLSLDGQESCKPALCGPEDQKTISTYKRSFFESESIKTLVLQFLQQYYFIYDNGDREGLLNAYHADACFSLTVPFSTMDLSASSVCEYVKYSRSMKVLKDPYMRKQLLKHKKC-DIIHFLRALPKTQHDLTSFSVDICFQTEKTLCFSVSGLFKEVEGSSQG-------CFHAFTRIFVAT-WDNSDLCIINDKLSVRNVYGFPSAS---NAVDTCSSSRLPSLSQDQQQMMPTFC------------------------------------------------------------SQSGVNVERSQKCLHDDQWNYNKAIQSFALLKVKDTVPEDKTTHTSPRS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H4D5-1", "uniprot_id": "NXF3_HUMAN", "id": "Q9H4D5-1", "name": "Nuclear RNA export factor 3", "aln": "-------------------------------------------MSLPSGHTTGHTDQVVQRRARCWDIYQRRFSSRSEPVNPGMHSSSHQQQDGDAAMHGAHMDSP------VRYTPYTISPYNRKGSFRKQDQTHVNMEREQKPPERRME--------GNMPDGTLGSWFKITVPFGIKYNEKWLLNLIQNECS-VPFVPVEFHYENMHASFFVENASIAYALKNVSGKIWDEDNEKISIFVNPAGIPHFVHRELKSEKVEQIKLAMN------QQCDVSQEALDIQRLPFYPDMVNRDTKMASNPRKCMAASLDVHEENIPTVM------------------------------------SAGEMDKWKGIEPGEKCADRSPVCTTFSDTSSNINSILELFPKLLCLDGQQSPRATLCGTEAHKRLPTCKGSFFGSEMLKNLVLQFLQQYYLIYDSGDRQGLLSAYHDEACFSLSIPFNPEDSAPSSFCKFFKDSRNIKILKDPYLRGELLKHTKL-DIVDSLSALPKTQHDLSSFLVDMWYQTEWMLCFSVNGVFKEVEGQSQG-------SVLAFTRTFIATPGSSSSLCIVNDKLFVRDTSHQGTQSALFTLVPTAFSSSVPAFSQEQQKMLPS--------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9GZY0-1", "uniprot_id": "NXF2_HUMAN", "id": "Q9GZY0-1", "name": "Nuclear RNA export factor 2", "aln": "-------------------------------MCSTLKKCGTYRTEVAECHDHGSTFQGRKKGGSSFRDNFDKRSCHYEHGGYERPPSHCQENDGSVEMRDVHKD------QQLRHTPYSIRCE-RRMKWHSEDEIRITTWRNRKPPERKMS--------QNTQDGYTRNWFKVTIPYGIKYDKAWLMNSIQSHCS-DRFTPVDFHYVRNRACFFVQDASAASALKDVSYKIYDDENQKICIFVNHSTAPYSVKNKLKPGQMEMLKLTMN------KRYNVSQQALDLQNLRFDPDLMGRDIDIILNRRNCMAATLKIIERNFPELLSLNLCNNKLYQLDGLSDITEKAPKVKTLNLSKNKLESAWELGKVKGLKLEELWLEGNPLCSTFSDQSAYVSAIRDCFPKLLRLDGRELSAPVIVDIDSSETMKPCKENFTGSETLKHLVLQFLQQYYSIYDSGDRQGLLGAYHDEACFSLAIPFDPKDSAPSSLCKYFEDSRNMKTLKDPYLKGELLRRTKR-DIVDSLSALPKTQHDLSSILVDVWCQTERMLCFSVNGVFKEVEGQSQG-------SVLAFTRTFIATPGSSSSLCIVNDELFVRDASPQETQSAFSIPVSTLSSSSEPSLSQEQQEMVQAFS------------------------------------------------------------AQSGMKLEWSQKCLQDNEWNYTRAGQAFTMLQTEGKIPAEAFKQIS--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9H1B4-1", "uniprot_id": "NXF5_HUMAN", "id": "Q9H1B4-1", "name": "Nuclear RNA export factor 5", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MR--------RNTQDENMRKWFKVTIPYGIKYDKAWLMNSIQSNCS-VPFTPVDFHYIRNRACFFVQVASAASALKDVSYKIYDDENQKICIFVSHFTAPYSVKNKLKPGQMEMLKLTMN------KRYNVSQQALDLQNLRFDPDLMGRDIDIILNRRNCMAATLKITERNFPELLSLNLCNNKLYQLDGLSDITEKAPKVKTLNLSKNKLESAWELGKVKGLKLEELWLEGNPLCSTFSDQSAYVSAIRDCFPKLLRLDGRELSAPVIVDIDSSETMKPCKENFTGSETLKHLVLQFLQQ------------------------------------SNLCKYFKDSRNIKILKDPYLQRKLLKHTKCPRNVDSLSALPETQHDFTSILVDMWYQT-------VNTCFLPRAG-----------------------PESQRWWCLLS--LKWKDG----------LRVLILPSCGPSSLPLAAIPVCAS--------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LCE1-1", "uniprot_id": "A0ABK0LCE1_RAT", "id": "A0ABK0LCE1-1", "name": "", "aln": "--------------------------------------------------------------MSSFQEVSGNKNLYDEFHLDTVLPPQLQDNDGNMQIMDANGDPQMLYEQQLKSSLESLESS-YTFSVKEDCGTTYSACQEKTLSDEEMN--------RSILGEVFERWFKITIPNGKKYNKMWLINLLQSYCS-MGFTPVDFQYIRNGIQFFVQSTKTAVELMNINYQISDEENKKISIYVNSSSEPASVHYKLTAAQMHSLKLSMK------KRYDVSKKALYLGKLRFDQDLMDHGIDMFLNRRSCMTAALQIIQENFPELLSLNVSNNKIYWLDGLSELIEKAPHVKTLNLSRNLLRTAWELEKIRGLNLEQLWLEGNPLCSTFPDHSSYVSAILNYFPELSHLDGRKLFP--TIDINTLEIIKPRKESYKGSECLKNLLVQFMLQYYLIYDYGDRHSLLNAYHANACFSLAITFNSDKADMSSLEDYLKDNRNMKMLTNSFLRMQLLKHKKY-NIVTCLHELPKTQHDLNSYVVDICVQTEKMICFSVNGVFKEVEGKSWG-------SVRAFTRTFILTPDRHFRLCIVNDEMILRNANPAEARKAFSTTRPTVSYTQSCWNTHTDLKLCGMREGIV----------------------------------------------------RTSGNASERMKPSLHSRVRKDPQVNSSDTSSERSPWKLSSSSSTLLFVCFFLSHSPGQN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z8R9-1", "uniprot_id": "D3Z8R9_RAT", "id": "D3Z8R9-1", "name": "Tip-associated protein", "aln": "-------------------------------MWSSPDKDPEDRPSMIVLKNTN---SETQKHRYDLPYKRSETHCHSEYKMSHRRGFQGRKRGANYIWHKFDRRNN---HFNYPGTPYAVGLK-RRKERYSYEDRYFLTVWNDRKTEECED--------LYAERRATERWYKVTIPSGRKYEKTWLINSIQKLCT-VPFVPVDFHYDKNRARFFVQDAKIASALKDVNLKICDETSRKISLFVSPSVVPYSVQNKFSSEQMEHLKISIM------KRYDASQKALDLEKFRFDQDLMDKDIDMMLNRRSCMVATLQIIESNIPELLSLNLKNNKLYQLDGLSDMTEKAPQVKILNLSRNKLKSIFELEKVKELKLEELWLEGNPFCNCYLDDSEYISAVRDLFPKLLRLDGRELIVPTGMDIEAP---QLCKKTHNETELIKNLVLRFLKEYYLFYDNGDRLRLLDAYHDQACFSLSVPFNVSDPDLDNLEEYLKYNRDIKKQQDSNMRVQLLKHTKH-DIVTSLSLLPKTQHDLCSFWVDLCFHSEMMLCFSVNGLFKEVEGKCQG-------CIRAFTRIFIAIPCSDSRICIMNDELIVRNASPKEIQKAF-TSSPAPDTSLKPLLSAEQQEMVKSFS------------------------------------------------------------VQSGMKLDWSQKCLEDNEWDYTKAGEAFTALQNEGKIPKEFFK-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JX7-1", "uniprot_id": "NXF1_MOUSE", "id": "Q99JX7-1", "name": "Nuclear RNA export factor 1", "aln": "--------------------------------MADEGKSYNEHDD-RVSFPQ-----RRKKGRGPFRWKCGEGNRRSGRGGSGVQSSRFEEDDGDVAMNDPQDG------PRVRYNPYTNRPNRRGDGWHDRDRIHITVRRDRAPAERGG--------AGTSQDGTTKNWFKITIPYGRKYDKTWLLSMIQSKCS-VPFNPIEFHYENTRAHFFVEDATTASALKGVNHKIQDRENRRISIIINASAPPYTVQNELKPEQIEQLKLIMS------KRYDGNQQALDLKGLRSDPDLVAQNIDVVLNRRSCMAATLRIIEENIPELLSLNLSSNRLYKLDDMSSIVQKAPNLKTLNLSGNELKTERELDKIKGLKLEELWLDRNPMCDNFGDQSSYISAIRERFPKLLRLDGHELPPPISFDVEAPTMLPPCKGSYFGTENLKSLVLRFLQQYYVIYDSGDRQGLLYAYHDGACCSLSIPYNPQNPVRKNLAEYVKDSRNVKKLKEPTQRFRLLKHTRL-NVVAFLNELPKTQHDVNAFVVDISAQTSTLLCFSVNGVFKEVDGKSRD-------SLRAFTRTFIAVPASNSGLCIVNDELFVRNASPEEIQRAFAMSAPTPSSSPVPTLSPEQQEMLQAFS------------------------------------------------------------TQSGMNLEWSQKCLQDNNWDYTRSAQAFTLLKAKGEIPEVAFMK----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88984-1", "uniprot_id": "NXF1_RAT", "id": "O88984-1", "name": "Nuclear RNA export factor 1", "aln": "--------------------------------MADEGKSYNEHDD-RVSFPQ-----RRKKGRGPFRWKCGVGNRRSGRGGSGIRSSRFEEDDGDVAMNDPQDG------PRVRFNPYTTRPNRRRDTWHDRDRIHVTVRRDRAPQERGG--------AGTSQDGTTKNWFKITIPYGKKYDKMWLLSMIQSKCS-VPFNPIEFHYENTRAHFFVENATTASALKAVNYKIQDRENGRISIIINSSAPPYIVQNELKPEQVEQLKLIMS------KRYDGSQQALDLKGLRSDPDLVAQNIDVVLNRRGCMAAALRIIEENIPELLSLNLSNNRLYKLDDMSSIVQKAPNLKILNLSGNELKSEWELDKIKGLKLEELWLDRNPMCDTFLDQSTYISTIRERFPKLLRLDGHELPPPIAFDVEAPTMLPPCKGSYFGTENLKSLVLHFLQQYYAIYDSGDRQGLLDAYHDGACCSLSTPSNPQNPVRHNLAKYFNDSRNVKKIKDTTTRFRLLKHTRL-NVVAFLNELPKTHHDVNSFVVDISAQTSTLLCFSVNGVFKEVDGKSRD-------SLRAFTRTFIAVPASNSGLCIVNDELFVRNASPEEIQRAFAMPAPTPSSSPVPTLSQEQQDMLQAFS------------------------------------------------------------TQSGMNLEWSQKCLQDNNWDYTRSAQAFTHLKAKGEIPEVAFMK----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBU9-1", "uniprot_id": "NXF1_HUMAN", "id": "Q9UBU9-1", "name": "Nuclear RNA export factor 1", "aln": "--------------------------------MADEGKSYSEHDDERVNFPQ-----RKKKGRGPFRWKYGEGNRRSGRGGSGIRSSRLEEDDGDVAMSDAQDG------PRVRYNPYTTRPNRRGDTWHDRDRIHVTVRRDRAPPERGG--------AGTSQDGTSKNWFKITIPYGRKYDKAWLLSMIQSKCS-VPFTPIEFHYENTRAQFFVEDASTASALKAVNYKILDRENRRISIIINSSAPPHTILNELKPEQVEQLKLIMS------KRYDGSQQALDLKGLRSDPDLVAQNIDVVLNRRSCMAATLRIIEENIPELLSLNLSNNRLYRLDDMSSIVQKAPNLKILNLSGNELKSERELDKIKGLKLEELWLDGNSLCDTFRDQSTYISAIRERFPKLLRLDGHELPPPIAFDVEAPTTLPPCKGSYFGTENLKSLVLHFLQQYYAIYDSGDRQGLLDAYHDGACCSLSIPFIPQNPARSSLAEYFKDSRNVKKLKDPTLRFRLLKHTRL-NVVAFLNELPKTQHDVNSFVVDISAQTSTLLCFSVNGVFKEVDGKSRD-------SLRAFTRTFIAVPASNSGLCIVNDELFVRNASSEEIQRAFAMPAPTPSSSPVPTLSPEQQEMLQAFS------------------------------------------------------------TQSGMNLEWSQKCLQDNNWDYTRSAQAFTHLKAKGEIPEVAFMK----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58H6Y3-1", "uniprot_id": "A0AC58H6Y3_DANRE", "id": "A0AC58H6Y3-1", "name": "", "aln": "MSRYREWYPNLSVITRVCSSSSDSSGSTVVREVWHADRSFTGQDGHLVGVRQSWGSVKANLHNGPARLLHGSGAR--GRCGSGPRG-RMQNSSMDVSLMNGQFGT-----AKQRFIPYR-RPSWRGEGQVEMIGEGNKQRFRVGDEKKGGKQWFKMTLCFLQLLDASRVPLKQPIPHGKKYDKRWLLTSLQNLCP-IAFTPLHYTTEGDKVHFYLEDTTTASALSKLSRRILDSDGQRVVVLMNSCYFPPFLKSELRLEDLELLKLCLS------KRFDDSQKSLDLTSIRTDPELVSHNVDIILNRKNCMQAVIKIIQESIPELLSLNLSKNKLYKLDGLTELVNKAPNLQSLNLSCNELKSHCELDKVKGFRLVELCLDGNPLCDRFKDQTTYISAVQKCFPRLLRLDGHVLSLPICFEVETSSNIPLCKGSHFVSNEIQGLIQRFLEQYYSIYDSGDRQPLLEAYHESACFSLCLPSIS-NPSRYKL-DYFKNSRNVKNIKDSPTRFRLLKHTRL-TVVACLNELPKTQHDINSINVDVNAYASTLLAFTVSGVFKEVDDQSED-------LFKAFSRVFVTVPAQNSGLCIVNDELFVRNTTMEEIQCAFTTPTQSPSSSPVPILSAYQQEMLSAFS------------------------------------------------------------QMSEMNLQWSQKCLEDNAWDFQQAAQIFAELQAHGMIPEAAFIK----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9U1H9-1", "uniprot_id": "NXF1_DROME", "id": "Q9U1H9-1", "name": "Nuclear RNA export factor 1", "aln": "----------------------------------MPKRGGGSSQRYNNNVGNGGGRYNAPEDFDDFDVEDRQRRKDRNKRRVSFKPSQCLHNKKDIKLRPEDLR--------------RWDEDDDMSDMTTAVKDRPTSRRRGSPIPRGKFG---------KLMPNSFGWYQVTLQNAQIYEKETLLSALLAAMSPHVFIPQYWRVERNCVIFFTDDYEAAERIQHLGKNGHLPDGYRLMPRVRSGIPLVAIDDAFK----EKMKVTMA------KRYNIQTKALDLSRFHADPDLKQVFCPLFR--QNVMGAAIDIMCDNIPDLEALNLNDNSISSMEAFKGVEKRLPNLKILYLGDNKIPSLAHLVVLRNLSILELVLKNNPCRSRYKDSQQFISEVRRKFPKLVKLDGETLEPQITFDLSEQGRLLETKASYLCDVAGAEVVRQFLDQYFRIFDSGNRQALLDAYHEKAMLSISMPSASQAGRLNSFWKFNRNLR--RLLNGEENRTRNLKYGRL-ACVSTLDEWPKTQHDRRTFTVDLTIYNTSMMVFTVTGLFKELNDETNNPASMELYDVRHFARTYVVVPQNNG-FCIRNETIFITNATHEQVREFKRSQHQPAPGAMPSTSSAVTSPQAGAAAGLQGRLNALGVATGPVAILSGDPLAATAPVNSGSAAISTTAVAPGAQDESTKMQMIEAMSAQSQMNVIWSRKCLEETNWDFNHAAFVFEKLFKENKIPPEAFMK----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99257-1", "uniprot_id": "MEX67_YEAST", "id": "Q99257-1", "name": "mRNA export factor MEX67", "aln": "---------------------------------------------MSGFHNVGNINMMAQQQMQQNRIKISVRNWQNATMN---DLINFISRNARVAVYDAHVEG--------PLVIGYVNSKAEAESLMKWNGVRFAGSNLKFELLDNNG---------ASAGTSDTISFLRGVLLKRYDPQTKLLNLGALHSDPELIQKGVFSSISTQSKMFPAMMKLASTEKSLIVESVNLADNQLKDISAISTLAQTFPNLKNLCLANNQIFRFRSLEVWKNKFKDLRELLMTNNPITTDKLYRTEMLRLFPKLVVLDNVIVRDEQKLQTVYSLPMKIQQFFFENDALGQSSTDFATNFLNLWDNNREQLLNLYSPQSQFSVSVDSTIPPSTVTDSDQTPAFGYYMSSSRNISKVSS-EKSIQQRLSIGQESINSIFKTLPKTKHHLQEQPNEYSMETISYPQINGFVITLHGFFEETG--KPELESNKKTGKNNYQKNRRYNHGYNSTSNNKLSKKSFDRTWVIVPMNNSVIIASDLLTVRAYSTGAWKTASIAIAQPPQQQASVLPQVASMN--------------PNITTPPQPQPSVVPGGMSIPGAPQGAMVMAPTLQLPPDVQSRLNPVQLELLNKLH---------------------------------------------------------------LETKLNAEYTFMLAEQSNWNYEVAIKGFQSSMNG--IPREAFVQF---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ::. : : :: * : . . : . : :: . . * .: : : .. .: : . . * .. .: :.. * .: : . . . : . . : : .. : .. .: : . ", "identical_positions": 4, "similar_positions": 57, "identity": "0.53%" }, { "cls_id": "homologset.agr.SGD:S000006091", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70580-1", "uniprot_id": "PGRC1_RAT", "id": "P70580-1", "name": "Membrane-associated progesterone receptor component 1", "aln": "--MAAED---VVATGADPSELEGGG-----------------------LLQEIFTSPLNLLLLGLCIFLLYKIVR--GDQPGASGDNDDDEPPP---LPRLKPRDFTPAELRRYDGVQ-DPRILMAINGKVFDVTKGRKFYGPEGPYGVFAGRDASRGLATFCLDKEALKDEYDDLS---DLTPAQQETLNDWDSQFTFKYHHVGKLLKEGEEPTVYSDDEEPK-------------------DEAARKSD------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55022-1", "uniprot_id": "PGRC1_MOUSE", "id": "O55022-1", "name": "Membrane-associated progesterone receptor component 1", "aln": "--MAAED---VVATGADPSELEGGG-----------------------LLHEIFTSPLNLLLLGLCIFLLYKIVR--GDQPGASGDNDDDEPPP---LPRLKRRDFTPAELRRFDGVQ-DPRILMAINGKVFDVTKGRKFYGPEGPYGVFAGRDASRGLATFCLDKEALKDEYDDLS---DLTPAQQETLSDWDSQFTFKYHHVGKLLKEGEEPTVYSDDEEPK-------------------DETARKNE------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00264-1", "uniprot_id": "PGRC1_HUMAN", "id": "O00264-1", "name": "Membrane-associated progesterone receptor component 1", "aln": "--MAAED---VVATGADPSDLESGG-----------------------LLHEIFTSPLNLLLLGLCIFLLYKIVR--GDQPAASGDSDDDEPPP---LPRLKRRDFTPAELRRFDGVQ-DPRILMAINGKVFDVTKGRKFYGPEGPYGVFAGRDASRGLATFCLDKEALKDEYDDLS---DLTAAQQETLSDWESQFTFKYHHVGKLLKEGEEPTVYSDEEEPK-------------------DESARKND------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80UU9-1", "uniprot_id": "PGRC2_MOUSE", "id": "Q80UU9-1", "name": "Membrane-associated progesterone receptor component 2", "aln": "--MAAGDGDVKLSTLGSGGESGGDG---SPGGAGATAARSSWVAA---LLATGGEMLLNVALVALVLLGAYRLWVRWGRRGLCSGPGAGEESPAAT-LPRMKKRDFSLEQLRQYDGAR-TPRILLAVNGKVFDVTKGSKFYGPAGPYGIFAGRDASRGLATFCLDKDALRDEYDDLS---DLNAVQMESVREWEMQFKEKYDYVGRLLKPGEEPSEYTDEEDTK-------------------DHSKQD--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XIU9-1", "uniprot_id": "PGRC2_RAT", "id": "Q5XIU9-1", "name": "Membrane-associated progesterone receptor component 2", "aln": "--MAAGDGDVKLSTLGSGGERGGDG---SPGGAGATAARSSWVAA---LLATGGEMLLNVALVALVLLGAYRLWVRWGRRGLCSGPGAGEESPAAT-LPRMKKRDFSLEQLRQYDGAR-TPRILLAVNGKVFDVTKGSKFYGPAGPYGIFAGRDASRGLATFCLDKDALRDEYDDLS---DLNAVQMESVREWEMQFKEKYDYVGRLLKPGEEPSEYTDEEDTK-------------------DHSKQD--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15173-1", "uniprot_id": "PGRC2_HUMAN", "id": "O15173-1", "name": "Membrane-associated progesterone receptor component 2", "aln": "--MAAGDGDVKLGTLGSGSESSNDGGSESPGDAGAAAEGGGWAAAALALLTGGGEMLLNVALVALVLLGAYRLWVRWGRRGLGAGAGAGEESPATS-LPRMKKRDFSLEQLRQYDGSR-NPRILLAVNGKVFDVTKGSKFYGPAGPYGIFAGRDASRGLATFCLDKDALRDEYDDLS---DLNAVQMESVREWEMQFKEKYDYVGRLLKPGEEPSEYTDEEDTK-------------------DHNKQD--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXM4-1", "uniprot_id": "Q9VXM4_DROME", "id": "Q9VXM4-1", "name": "", "aln": "MDSKVGADPSSAYDKEIGNNLNNDD--------------SSFLGN---IIREILYSPMNLALLAIICFLVYKIVR---DRTEVPSVGVAKPSEPE--LPKIR-RDFTVKELRQYDGTQPDGRVLVAVNGSVYDVSKGRRFYGPGGPYATFAGRDASRNLATFSVVSID-KDEYDDLS---DLSAVEMDSVREWEMQFKEKYELVGKLLRKGEEPTNYDDDEDEENVNNDEQERKNLPKSKTETDDTKQEKESHILQSNVTNKNNAQDQATPSTDC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12091-1", "uniprot_id": "DAP1_YEAST", "id": "Q12091-1", "name": "Damage response protein 1", "aln": "-----------------------------------------------------------MSFIKNLLFGGVKTSE---DPTGLTGNGASNTNDSNKGSEPVVAGNFFPRTLSKFNGHD-DEKIFIAIRGKVYDCTRGRQFYGPSGPYTNFAGHDASRGLALNSFDLDVIKDWDQPIDPLDDLTKEQIDALDEWQEHFENKYPCIGTLIP---EPGVNV---------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VJY5-1", "uniprot_id": "Q9VJY5_DROME", "id": "Q9VJY5-1", "name": "Cytochrome b5 heme-binding domain-containing protein", "aln": "-----------MAESSKGMEHTTSWY--------------------CKLYNSLKETPIDVTLLIMSIVVFLKLGF-FARRLSREEPDFSDDNNQEVDLPPLR-KDFTVRELREYDGTRADGRILVAILFNIYDVSRSVHYYGRNGVNPNYAGRDISR-ILINSPEDLKDSEDFDDLS---DLSRNQMNTLREWEQRYKMKYPFVGKLKEKLQINEEEDFELQQA--------------------DPLVD--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: . : . . : :* * .::* ::::*: .::* ::. ::** * :**:* ** : . : : :. **. : ::: :*: :: ** :* * ", "identical_positions": 20, "similar_positions": 43, "identity": "7.27%" }, { "cls_id": "homologset.agr.SGD:S000006093", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LVF4-1", "uniprot_id": "F1LVF4_RAT", "id": "F1LVF4-1", "name": "Protoheme IX farnesyltransferase, mitochondrial", "aln": "---MAASPHTISSRLLTGSVGRSVWYLERRAIQGLPHRVTRLFRNVTN-QWVTVQHLSFLKRMYVTQLHRGLNQRVKPKPAPPASPLLEHTSSGQARAEVDELPPFPAPSLPLSQKPNE--LMELEATSIVDHSLDTAKEQKEERQWKEMKLHTDDLPGILARLSKIKLTALVVSTTSAGFALAPCPFDWSCFLLTSLGTGLASCAANSINQFFEVPFDSNMSRTKNRPLVRGQISPLLAVSFATCCAVPGVALLTWGVNPLTGALGVFNIFLYTCCYTPLKRVSIANTWVGAVVGAIPPVMGWTAATGSLDAGALLLGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPALCRRVALRHCLALIALSTTAPVLDITTWVFPVISLPINLYISYLGFRFYVDA---------------------DRKSSRKLFFCSLWHLPLLLLLMLTCKQ-----RPGQEGDKGEAPS-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CFY5-1", "uniprot_id": "COX10_MOUSE", "id": "Q8CFY5-1", "name": "Protoheme IX farnesyltransferase, mitochondrial", "aln": "---MAASPHTISSRLLTGSVGGCIWYLERRAIQGLPHRVTRLFRNVSN-QWVTLQHLSFLKRMYVTQLHRGLSQRVKPKPEPPASPFLEHTSSGQARADEDELPSFPAPSRPLSRKPNEE-LVELEATSIVDHSLDTAKEKKEERQWKEMKLHTDDLPGILARLSKIKLTALVVSTTSAGFALAPGPFDWSCFLLTSLGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCAVPGVALLTWGVNPLTGALGVFNIFLYTCCYTPLKRVSITNTWVGAVVGAIPPVMGWTAATGSLDAGALLLGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPALCRRVALRHCLALIALSTAAPVLDITTWVFPVISLPINLYISYLGFRFYVDA---------------------DRRSSRKLFFCSLWHLPLLLLLMLTCKQ-----RPGQEGDKGEAPS-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12887-1", "uniprot_id": "COX10_HUMAN", "id": "Q12887-1", "name": "Protoheme IX farnesyltransferase, mitochondrial", "aln": "---MAASPHTLSSRLLTGCVGGSVWYLERRTIQDSPHKFLHLLRNVNK-QWITFQHFSFLKRMYVTQLNRSHNQQVRPKPEPVASPFLEKTSSGQAKAEIYEMRPLSPPSLSLSRKPNEKELIELEPDSVIEDSIDVGKETKEEKRWKEMKLQVYDLPGILARLSKIKLTALVVSTTAAGFALAPGPFDWPCFLLTSVGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCAVPGVAILTLGVNPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGWTAATGSLDAGAFLLGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDA---------------------DRRSSRRLFFCSLWHLPLLLLLMLTCK------RPSGGGDAGPPPS-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKZ1-1", "uniprot_id": "Q9VKZ1_DROME", "id": "Q9VKZ1-1", "name": "Protoheme IX farnesyltransferase, mitochondrial", "aln": "------------MILFKG------------------------IRRVQS-QLRTPVDLVLIRYSTAATIASQDDKGVTTASPVSQAGKVQHLPDSQITWMP---SPYTMPGKTLSQ---------------------------------------------YKKLSKFRLTSLVVITTMGGYAMAPAAFDPTTFAMCTLGTGLVSAAANAINQYHEVPFDSQMSRTKNRVLVTGQMTPLHAVTFAAVSATAGLSMLYFGVNGLTAALGAGNLFLYTTIYTPMKRISIVNTWVGSIVGAIPPLMGWAGCAATLDAGAMILAGVLYAWQFPHFNALSWNLRPDYSRAGYRMMAVTNPGLCRRTALRYSVAIVGLSAMAPVLDVTNYWFALETLPLNAYFAYLAYKFHEKS---------------------DSGSSRKLFRFSLIHLPALMLLFLTNKKEWYFSKPAGEENKKESTYSAIKHSASSLGNVLPVAVAEGPR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21592-1", "uniprot_id": "COX10_YEAST", "id": "P21592-1", "name": "Protoheme IX farnesyltransferase, mitochondrial", "aln": "MSYFPRTYAHLMRNVLAHNKGNIYLQIGTQLHDTQIKIRFNGVRYISRNHGGKQQHINTAPIEFTPNFGYGDRTSNCNKKVESTAMKTLRCTDDISTSSGSEATTDASTQLPFNVKLVDP------------MVRKSKRPSHAISEGLNMKTLKKKVIMPYLQLTKPRLTILVMLSAICSYALSPYPASVNELLCLTVGTTLCSGSANAINMGREPEFDRQMVRTQARPVVRGDVTPTQAFEFAALIGTLGVSILYFGVNPTVAILGASNIALYGWAYTSMKRKHIINTWLGALVGMVPPLMGWAAASPLSHPGSWCLAGLLFAWQFPHFNTLSHNIRNEYKNAGYVMTAWKNPLLNARVSLRYSILMFPLCFGLSYFNITDWYYQIDSGLINAWLTFWAFKFYWQQRINYSAKTLKDNVKFNKGLSVANIYARKTFMASVLHLPAILILAIIHKKGRWDWIYPGEAKRPQERF-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .* : : . .: .. : : : ... . . . .:. :*:* :** **: :: .:*::* . . : ::** * * :**:** * ** :* **: * :* *:::* *. **: .. *:::* *** .. ** *: ** **.:** * ***:*::** :**:***:..: ..*: *.*:*::*******:** .:* :*...** * : .:* * *.:**:.: :. *. . :::* : : : : :* :::: .::*: . :*: * *: *** :::* : * . ", "identical_positions": 91, "similar_positions": 117, "identity": "18.31%" }, { "cls_id": "homologset.agr.SGD:S000006094", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66H47-1", "uniprot_id": "RM24_RAT", "id": "Q66H47-1", "name": "Large ribosomal subunit protein uL24m", "aln": "-----MRLSALLALASK------------------------------ATLSPHYRYGMSRPGSIADKRKNPPWSRRRPVVVEPISDEDWHLFCGDMVEILEGKDAGKQGKVVQVVRQRNWVVLEG-----------------------------LNTHYRYIGRTKDHRG-----TMIPSEAPL-----------------------LHHQVKLVDPVDRKPTEIQWRFTEAGERVRVSTRSGRIIPKPEFP--RADGIVPETWTDGPKDTSVEDALERTYVPR---------------LKTLEEDVMEAMGIQETRRFKKIYWY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ06-1", "uniprot_id": "RM24_MOUSE", "id": "Q9CQ06-1", "name": "Large ribosomal subunit protein uL24m", "aln": "-----MRLSALLALASK------------------------------ATSSPFYRYGMSRPGSIADKRKNPPWSRRRPVVVEPISDEDWHLFCGDMVEILEGKDAGKQGKVVQVVRQRNWVVLEG-----------------------------LNTHYRYIGRTKDHRG-----TMIASEAPL-----------------------LHHQVKLVDPVDRKPTEIQWRFTEAGERVRVSTRSGRIIPKPEFP--RADGIVPETWTDGPKDTSVEDALERTYVPR---------------LKTLEEDVMEAMGIQETRRFKKVYWY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96A35-1", "uniprot_id": "RM24_HUMAN", "id": "Q96A35-1", "name": "Large ribosomal subunit protein uL24m", "aln": "-----MRLSALLALASK------------------------------VTLPPHYRYGMSPPGSVADKRKNPPWIRRRPVVVEPISDEDWYLFCGDTVEILEGKDAGKQGKVVQVIRQRNWVVVGG-----------------------------LNTHYRYIGKTMDYRG-----TMIPSEAPL-----------------------LHRQVKLVDPMDRKPTEIEWRFTEAGERVRVSTRSGRIIPKPEFP--RADGIVPETWIDGPKDTSVEDALERTYVPC---------------LKTLQEEVMEAMGIKETRKYKKVYWY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DH02-1", "uniprot_id": "RM24_DANRE", "id": "Q6DH02-1", "name": "Large ribosomal subunit protein uL24m", "aln": "-----MRLTALLSMAAK------------------------------VALPHGYRYGTNRPWTIAARRLNPPGKRRRKVFVEPIANEDWPVVRGDTVEVLSGKEKGKQGKVAQVIRARNWVILEG-----------------------------LNTHYRYVGRSGDYRG-----TYLASEAPL-----------------------LLKDIALIDPTDRKPTEIQWRYTEEGERVRVSVRTGRIIPKPVFQ--RKDGIVPQQWKDGPKDTSPEDTLQKTYTPS---------------LKTLEEEVMEKMNIQENRRPRKSYWY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMY1-1", "uniprot_id": "RM24_DROME", "id": "Q9VMY1-1", "name": "Large ribosomal subunit protein uL24m", "aln": "-----MRLTQYLASKLKNFSNLPKEYIERSKKQVYWQTPKEINYLPRTVERKRFRYTTNRSWTGQFRQQNMPGTVRRKVLVEPI--EDWSFFRGDRIEVLVGKDKGKQGIVTQVIPERNWVIVEG-----------------------------LNWHYRKVGGEKEFPG-----IIIKSEAPLH----------------------VTKDIRLVDPSDLQGTDFEWRFTEEGEKVRVSLRSGRIIPIPETNNQTHDYKTPNAYIEREKDTPGAVVGEITFQPK---------------LSTFEMDIMEEMGIKEERTPVKSYWY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36534-1", "uniprot_id": "RM40_YEAST", "id": "P36534-1", "name": "Large ribosomal subunit protein uL24m", "aln": "MSGSYQHLSNVGSRVMKR----------------------------LGNRPKNFLPHSEKFIKKSTPEFMKSDLKEVDEKTSFKSEKEWKFIPGDRVVVMSGASKGNIAVIKSFDKRTNSFILDENGPTKTVPVPKQFWLEGQTSHMITIPVSILGKDLRLVADIDDEKTPGKTRTVAVRDVSFNGSYYDADYKKVMPYRCVKGQPDLIIPWPKPDPIDVQTNLATDPVIAREQTFWVDSVVRNPIPKKAIPSIRNPHSKYKRGTLTAKDIAKLVAPEMPLTEVRKSHLAEKKELAEREVPKLTEEDMEAIGARVFEFLEKQKRE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: : * : . . . . . .. ::* .. ** : :: * . *: . : .. * .:: *. . * :. : :..: : ** * : . : . *. . ** : ** . . : . : .: : ** :. : . * ", "identical_positions": 21, "similar_positions": 56, "identity": "6.46%" }, { "cls_id": "homologset.agr.SGD:S000006095", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JK25-1", "uniprot_id": "CLIP1_RAT", "id": "Q9JK25-1", "name": "CAP-Gly domain-containing linker protein 1", "aln": "-----------------------------------------------MSMLKPSGLKAPTKILKPGSTALKT--------PAAAAAPLEKTVPSEKASGPPSS-----------ETQEEFVDDFRVGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRPSKLTRKVQAEDEANGLQTAHA-RAASPLSTAAATMVSSSPATPSNIPQKPSQPVAKETSATPQISNLTKTASESISNLSEAGSVKKG-ERELKIGDRVLVG---GTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVHKVTKIGFPSTTPAKAKAAAVRRVMATTPASLKRSPSA---------SSLSSMSSVASSVSSKPSRTGLLTETSSRYARKISG-----------TTALQEALKEKQQHIEQLLAERDLER---AEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAAD------------------------------REKVELLNQLEEEKRKVEDLQFRVEEESITKGDLET-----------QTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEK---------------SRIMELEKDLALRVQEVAELRRRLE--------SSKPPGDVDMSLSLLQEISALQEKLEVTHTDHQNEVTSLKDHFGTREEMFQKEIKALHAATEKLSKENESLRSKLDH------ANKENSDVIALWKSKLETAIASHQQAMEELKVS-------------------------------FSKGIG-------TDSAEFAELKTQIERLRLDYQHEIESLQSKQD-----------------SERSAHAKEMESMKAKLMKIIKEKEDSLEAVKARLDTAED---------------------------------------------QHLVEMEEMLSKLQEAEIK-------------------------------------------------------------------------------------------------------------------KEKFASASEEAVSTQTSMQDTVNKLHQKEEQFNMLSSELEKLREN----LTDMEAKFKEKDERED-------------QLVKAKEKLENDIAEIMKMSGDNSSQ-----LTKMNDELRLKERSVEELQLKLTKANENASLLQKSIGEVTLKAEQSQ-------------QEAAKKHEEEKKELENKLLELEKKMETSHYQCQDLKAKYEKASSETKIKHEEILQNFQKMLVDTEDKLKAAQEANRDLMQDMEELKSQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQS-----------ELDTLKENNLKTVEELNKSKELLNEENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERS-VLNNQLLEMKKSLPSNTLRESEYRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDVQTEEDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGEDPNSYDSDDQEKQSKKKPRLFCDICDCFDLHDTEDCPTQAQMSEDPPHSTHHGSRSEE-------RPYCEICEMFGHWATNCNDDETF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q922J3-1", "uniprot_id": "CLIP1_MOUSE", "id": "Q922J3-1", "name": "CAP-Gly domain-containing linker protein 1", "aln": "-----------------------------------------------MSMLKPSGLKAPTKILKPGSTALKT--------PAAAAAPVEKTIPSEKASGPPSS-----------ETQEEFVDDFRVGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRPSKLTRKVQAEDEANGLQAAPG-RTASPLSTAAATMVSSSPATPSNIPHKPSQSTAKEPSATPQISNLTKTASESISNLSEAGSVKKG-ERELKVGDRVLVG---GTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVHKVTKIGFPSTTPAKAKAAAVRRVMAATPASLKRSPSA---------SSLSSMSSVASSVSSKPSRTGLLTETSSRYARKISG-----------TTALQEALKEKQQHIEQLLAERDLER---AEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAAD------------------------------REKVELLNQLEEEKRKVEDLQFRVEEESITKGDLE----------------------------------------------VATVSEK---------------SRIMELEKDLALRAQEVAELRRRLE--------SSKPPGDVDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKALHTATEKLSKENESLRSKLDH------ANKENSDVIALWKSKLETAIASHQQAMEELKVS-------------------------------FSKGIG-------TDSAEFAELKTQIERLRLDYQHEIESLQSKQD-----------------SERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAED---------------------------------------------QHLVEMEDTLNKLQEAEIKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLREN----LTDMEAKFKEKDDRED-------------QLVKAKEKLENDIAEIMKMSGDNSSQ-----LTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQ-------------QQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQN-----------ELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERS-VLNNQLLEMKK-------RESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERAQESQ--IDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGEDLNSYDSDDQEKQSKKKPRLFCDICDCFDLHDTEDCPTQAQMSEDPPHSTHHGSRSEE-------RPYCEICEMFGHWATNCNDDETF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30622-3", "uniprot_id": "CLIP1_HUMAN", "id": "P30622-3", "name": "CAP-Gly domain-containing linker protein 1", "aln": "-----------------------------------------------MSMLKPSGLKAPTKILKPGSTALKT--------PTAVVAPVEKTISSEKASSTPSS-----------ETQEEFVDDFRVGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRPSKLTRKVQAEDEANGLQTTPASRATSPLCTSTASMVSSSPSTPSNIPQKPSQPAAKEPSATPPISNLTKTASESISNLSEAGSIKKG-ERELKIGDRVLVG---GTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVHKVTKIGFPSTTPAKAKANAVRRVMATTSASLKRSPSA---------SSLSSMSSVASSVSSRPSRTGLLTETSSRYARKISG-----------TTALQEALKEKQQHIEQLLAERDLER---AEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAAD------------------------------REKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQISEDPENTQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEK---------------SRIMELEKDLALRVQEVAELRRRLE--------SNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEH------ANKENSDVIALWKSKLETAIASHQQAMEELKVS-------------------------------FSKGLG-------TETAEFAELKTQIEKMRLDYQHEIENLQNQQD-----------------SERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAED---------------------------------------------QHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLREN----LADMEAKFREKDEREE-------------QLIKAKEKLENDIAEIMKMSGDNSSQ-----LTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQ-------------QEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQN-----------ELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERS-VLNNQLLEMKK-------RESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQ--IDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGDDLNNYDSDDQEKQSKKKPRLFCDICDCFDLHDTEDCPTQAQMSEDPPHSTHHGSRGEE-------RPYCEICEMFGHWATNCNDDETF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q4W2-1", "uniprot_id": "A0A8M9Q4W2_DANRE", "id": "A0A8M9Q4W2-1", "name": "", "aln": "-----------------------------------------------MNMLKSSGLKIPGRGPKHASPVGRTT-----AGPSTSPAAQKEGCPYKQTTPTPSSNASDKSSSKASEVGDEVAGDFVVGERVWVNGVKPGVIAYLGETQFSPGQWAGVVLNDLVGKNDGSVNGVRYFECQALQGIFTRPSKLTRQPIGDGSDE---------------QQNAQLQGGAGASGQRVVMPLREGILNSS---------VKTGNESGSNMSDSGSVKKGGEKDLKVGDRVLVG---GTKTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAKAKKSKR---MAMGVSSLAHSPSS---------SSISSVSSVASSVGGRPSRTGLLTETSSRYARKISG-----------TTALQEALKEKQQHIEQLLAERDLER---AEVAKATSHICEVEKELAALKARHLQYATETESNLQQVRAMLASTQ------------------------------KDKMELANQLEEEKRKVEDLQFRVEEESITKGDLET-----------QTKLEHARIRQLEQCLHLEKSKAERLQKELEEKMQTTVEEK---------------TRVMQLEEELALRKAEVEELQVRFQRGS-----SGSATDAEDGEPGITSETLVLREQLLSVGRERREESSQLRERYEASLSTSQKEIERLKAITERQGQEISDLKQRLQQ------ATRENMEMMDSWKAKLDALVGDHQRALEELKAS-------------------------------LTTDCGSGEINGGEGEGSLPEMRAALEGLKMEHQLELENLKAKHE-----------------IDAAVMAKEREDLRSRLQELRDQLEDSEENWKIQVETKSN---------------------------------------------QHTLEIKEVSEKLQKAELR-------------------------------------------------------------------------------------------------------------------------------------IVDLDKSHEEREKVNQLLKEQLMLAEKK---MVDYEALQKAEAQSRA-------------EILSLQEKLR-----------------------------------VTENRLQAVEADH-------TTQDVNMIENNDN-------------SDEKVKLKQNVEETLEKLTKREKEVSTLTTQVDALKT----------------------------------------------QITALEEKVRLGEKTADG------LIKEKTRLEAELETMTKKSHDASG-----------QLVNISQELLKKERSLNELRVLL-------------LESPRHSAG-----------VDRDLSREVHRAEWRMK-EQKLQDDIK-TLREKLLLLGR-----------ERSSPDHRRYSMMD----PSASDTEVARLRQRLLNTEDALRNALEHNQHVDQLVQAMRT--------------RPDKNQAHASANSANGIHQEDTSFTQEEEH-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJE5-1", "uniprot_id": "CL190_DROME", "id": "Q9VJE5-1", "name": "Restin homolog", "aln": "MSDDTSASGGTSAPFPSPVTADPEPGATASKLPGPIRSNIPTPATSGTGIPQPSKMKAPSSFGSTGSVSKIGRPCCNHTTPKSGPPPREATSMSRESDDNLSSIN-SAYTDNSSAVLTANTEQFIIGQRVWLGGTRPGQIAFIGDTHFAAGEWAGVVLDEPNGKNDGCVSGKRYFQCEPKRGIFSRLTRLTTYPLAG-----------------AQTPTSPLAKSSPDRSRTVS---------------------PTASIRSSMLRSPG---IGGKNGMAVGDRVIVSSGFGSRPGILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFVPIAKVSLSPSSKKTRLSRTGSRESLTSIGTMNSIATTATSRMRMNAQQRKSSTPVKPILATPKSQFSMQDLLREKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVELESALDNERKKTEELQCSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSILPPDLPSDDGALQEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSK-----DEALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLS-KFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEK--------GNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLAK--INFLNSIIADMQQKNDALKAKVQTLETLPMDFTKP-----HAFDALTKRKPAPRLFCDICDEFDQHDTEDCPIQGSEDQDYSTPSSESNNNEKERKLPAPRKYCDSCEVFGHDTSECADDETY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33420-1", "uniprot_id": "NIP80_YEAST", "id": "P33420-1", "name": "Protein NIP100", "aln": "--------------------------------------------------MRNAGVQVDTN-----------------------------------------------------------MQKISLQDTVLVN-EMKGRVKFIGETQFAKGIWYGIELDKPLGKNDGSANGIRYFDIDLKKANSNGGYYG------------------------LFCKKDTLQFYKPDDDEHSLLN------------------GNAAQETIKNLQVKCESLASKLNKIKIENHELKTS--VEKLSTNETVLLSKISRLDKLVKELKVENGNMKTHLDNFNHLLDASDSVMAPDLDKGTLLERSHLLQGLLDQTKLSYDKAMKVQEDLLEENT------------------------------QLLEENAVLSKKISD--------------LGLQLQQTNNTIGDLALQIEAQS-----------KSSNIVDKLTNDNILLTSNIKALNNELEELQAKEKLDEN------------------------------LRITYEQLEQELRLQLSNLQSALENEKEIAGTYIEE--------------------------------------------NSRLKAT--------------------LESIEAKTSHKFQSLELKVN-----------TLQEELYQNKLLKKFYQIYEPFAQPHLAALSSQLQYLAEVIESENFGKLENIEIHIILKVLSSISYALHIYTIK---------NTPDHLETTLQCFKVNIAPISMWLSEFLQR----------------------------------------------------------KFSSKQETAFSICQFLED----------------------NKFLDKDVTLILKILHPILETTVPKLLAFLRTNSN---------------------------------------------FNDNDTLCLIGSLYERSLS------------------------------------------------------------------------------------------------------------------------------------LIARIDKLIGKEEISKQDNRLFLYPSCDIT--LSSILTILFSDALFLR---------------------------------------------------------QDYKRISSLKKLEVFFQGIESLLENITIFPEQPS-------------------QQTSDSESQCNIKEGNFSNSLLSDRLNEENIR---------------------------------------------LKEVLVQKENMLTELETKIKIIIGRDLERKTLEENIKTLKVELNNKNE------------------ENCGKTEILNKLKEENFNLVNRLKNMELKLYQIKDNNTLNKIYLDREKVDRVNLVSEIMELRETIRRQIKEQKRVS------------------------------IDFSWLDELPAVENKQPFKEHINHSLDTLGIEMFNFVSTSRILDLKLDQPLAEDELWHERDHSYISYLKRKRKNIRLKSQNVVTYYK--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: .: : : * :. * : ::*:*:*: * * *: *:. *****.. * ***: : :. . : :.. . : . . : : :: : : . . : :.:: : **. *: . : . .:: .. : : * . . .: * * . : : * ::: : * :* : : . .:* . : :: :: : : . : :* : .::: *: . : . **. . : *. ... . : . : : . . : : : . *: : : : : :. :. . :.:: : . : :. : . * : : . .. : .* . :.. . * : . : . : : . : : .: : . : .: :: . . . : : : . . : .:: . . * : . : :. * * . : : :. . . . . . : : : . . : * : . ", "identical_positions": 41, "similar_positions": 203, "identity": "2.34%" }, { "cls_id": "homologset.agr.SGD:S000006096", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ADP6-1", "uniprot_id": "A0A8I6ADP6_RAT", "id": "A0A8I6ADP6-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit A", "aln": "MANRR-GGGQGQPPSVSPSPGSSGSLSTD---RTCTHNICMVSDFFYPNMGGVESHIYQLSQCLIERGHKVITVTHAYGNRKGVRYLTNGLKVYYLPLRVMYNQSTATTLFHSLPLLRYIFVRERITIIHSHSSFSAMAHDALFHAKTMGLQTVFTDHSLFGFADVSSVLTNKLLTVSLCDTNHIICVSYTSKENTVLRAALNPEIVSVIPNAVDPTDFTP-EP---FRRHDSV--ITVVVVSRLVYRKGTDLLSGIIPELCQKYQELNFLIGGEGPKRIILEEVRERYQLHDRVQLLGALEHKDVRNVLVQGHIFLNTSLTEAFCMAIVEAASCGLQVVSTKVGGIPEVLPENLIILCEP-SVKSLCEGLEKAIFQVKSGTLPAPENIHNVVKTFYTWRNVAERTEKVYERVSKESVLP---MHKRLDRLISHCGPVTGYIFALLAVLSYLFLIFLQWMTPDSVIDVAIDATGPRRAWTHQWPRDKKRDEN-DKVSKSR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64323-1", "uniprot_id": "PIGA_MOUSE", "id": "Q64323-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit A", "aln": "MANRR-GGGQGQPPSVSPSPGSSGNLSDD---RTCTHNICMVSDFFYPNMGGVESHIYQLSQCLIERGHKVITVTHAYGNRKGVRYLTNGLKVYYLPLRVMYNQSTATTLFHSLPLLRYIFVRERITIIHSHSSFSAMAHDALFHAKTMGLQTVFTDHSLFGFADVSSVLTNKLLTVSLCDTNHIICVSYTSKENTVLRAALNPEIVSVIPNAVDPTDFTP-DP---FRRHDSV--ITVVVVSRLVYRKGTDLLSGIIPELCQKYQELHFLIGGEGPKRIILEEVRERYQLHDRVQLLGALEHKDVRNVLVQGHIFLNTSLTEAFCMAIVEAASCGLQVVSTKVGGIPEVLPESLIILCEP-SVKSLCDGLEKAIFQVKSGTLPAPENIHNVVKTFYTWRNVAERTEKVYERVSKETVLP---MHKRLDRLISHCGPVTGYMFALLAVLSYLFLIFLQWMTPDSFIDVAIDATGPRRAWTHQWPRDKKRDEN-DKISQSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P37287-1", "uniprot_id": "PIGA_HUMAN", "id": "P37287-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit A", "aln": "MACRG-GAGNGHRASATLSRVSPGSLYTC---RTRTHNICMVSDFFYPNMGGVESHIYQLSQCLIERGHKVIIVTHAYGNRKGIRYLTSGLKVYYLPLKVMYNQSTATTLFHSLPLLRYIFVRERVTIIHSHSSFSAMAHDALFHAKTMGLQTVFTDHSLFGFADVSSVLTNKLLTVSLCDTNHIICVSYTSKENTVLRAALNPEIVSVIPNAVDPTDFTP-DP---FRRHDS---ITIVVVSRLVYRKGIDLLSGIIPELCQKYPDLNFIIGGEGPKRIILEEVRERYQLHDRVRLLGALEHKDVRNVLVQGHIFLNTSLTEAFCMAIVEAASCGLQVVSTRVGGIPEVLPENLIILCEP-SVKSLCEGLEKAIFQLKSGTLPAPENIHNIVKTFYTWRNVAERTEKVYDRVSVEAVLP---MDKRLDRLISHCGPVTGYIFALLAVFNFLFLIFLRWMTPDSIIDVAIDATGPRGAWTNNYSHSKRGGEN-NEISETR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S6Z8-1", "uniprot_id": "B0S6Z8_DANRE", "id": "B0S6Z8-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit A", "aln": "MGHRRRGHTHAPKTPTCLNAHSSNTVQHADHEQSVKHSICMVSDFFYPNMGGVESHIYQLSQCLIEKGHKVVIATHAYGDRRGIRYLTNGLKVYYLPLQVMYNQSTSTTCFHSLPLLRCIFVRECITIVHAHSSFSAMAHDALFHAKTMGLNTVFTDHSLFGFADLSSVLTNKLLTVSLCDTNHIVCVSYTSKENTVLRATLDPEIVSVIPNAVDPTDFTP-DP---CRRDNSK--ITIVVISRLVYRKGIDLLSGIIPELCGRHPDLCFLIGGEGPKRIILEEVREKYQLHDRVRLLGALDHKDVRDVLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEVLPNELVTLCGP-SVCSLCDGLETVIKKIRSGNVESPAAIHRKVRTLYTWRNVAERTEKVYNRVCREPVLP---LSARLHRLRSHCGAVAGSIFSFVAVINFLFLLFLQWLRPDSLIDVAVDASGPHSRLKQQVSHKTSKTANPNDLT---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32363-1", "uniprot_id": "GPI3_YEAST", "id": "P32363-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase GPI3 subunit", "aln": "----------------------------------MGFNIAMLCDFFYPQLGGVEFHIYHLSQKLIDLGHSVVIITHAYKDRVGVRHLTNGLKVYHVPFFVIFRETTFPTVFSTFPIIRNILLREQIQIVHSHGSASTFAHEGILHANTMGLRTVFTDHSLYGFNNLTSIWVNKLLTFTLTNIDRVICVSNTCKENMIVRTELSPDIISVIPNAVVSEDFKPRDPTGGTKRKQSRDKIVIVVIGRLFPNKGSDLLTRIIPKVCSSHEDVEFIVAGDGPKFIDFQQMIESHRLQKRVQLLGSVPHEKVRDVLCQGDIYLHASLTEAFGTILVEAASCNLLIVTTQVGGIPEVLPNEMTVYAEQTSVSDLVQATNKAINIIRSKALDT-SSFHDSVSKMYDWMDVAKRTVEIYTNISSTSSADDKDWMKMVANLYKRDGIWAKHLYLLCGIVEYMLFFLLEWLYPRDEIDLAP--KWPKKTVSNETKEARET-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..*.*:.*****::**** ***:*** **: **.*: **** :* *:*:**.*****::*: *::.::* .* * ::*::* *::** : *:*:*.* *::**:.::**:****.********:** :::*: .*****.:* : ::::*** *.*** ::*: *.*:*:******* . **.* :* :*.:* *.:**:.**. .** ***: ***::* : :: *::.*:*** * :::: * ::*:.**:***:: *:.**:** **.*:*::****** :**.***.* :*:*:*********:.: . ** .* :. :..* ::* : : :* * .:* * :**:** ::* .:. . : .* .: * : :: : .:..::::::*.*: * . **:* . *: .:: . ", "identical_positions": 182, "similar_positions": 161, "identity": "36.4%" }, { "cls_id": "homologset.agr.SGD:S000006097", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62351-1", "uniprot_id": "TFR1_MOUSE", "id": "Q62351-1", "name": "Transferrin receptor protein 1", "aln": "---MMDQARSAFSNLFGGEPLSYTRFSLARQVDGDNSHVEMKLAAD-EEENADNNMKASVRKP--KRFNG----------RLCFAAIALVIFFLIGFMSGYLGYCKRVEQKEECVKLAETEETDKSETMETEDVPTSSRLYWADLKTLLSE-KLNSIEFADTIKQLSQNTYTPREAGSQKDESLAYYIENQFHEFKFSKVWRDEHYVKIQVKSSIGQNMVTIVQSN---GNLDPVESPEGYVAFSKPTEVSGK-LVHANFGTKKDFEELSY---SVNGSLVIVRAGEITFAEKVANAQSFNAIGVLIYMDKNKFPV--------------VEADLALFGHAHLGTGDPYTPGFPSFN-HTQFPPSQSSGLPNIPVQTISRAAAEKLFGKMEGS-CPARWNIDSS-CKLELSQ----------NQNVKLIVKNVLKERR-ILNIFGVIKGYEEPDRYVVVGAQRDALGAGVAAKSSVGTGLLLKLAQVFSDMISKDGFRPSRSIIFASWTAGDFGAVGATEWLEGYLSSLHLKAFTYINLDKVVLGTS--NFKVSASPLLYTLMGKIMQDVKHPVDGKSLYRDSNWIS------------KVEKLSFDNAAYPFLAYSGIPAVSFCFCED------ADYPYLGTRLDTYEALTQKV-PQLNQMVRTAAEVAGQLIIKLTHDVELNLDYEMYNSKLLSFMKDLNQFKTDIRD------MGLSLQWLYSARGDYFRATSRLTTDFHNAEK--TNRFVMR---EINDRIMKVEYHFLSPYVSPRESPFRHIFWGSGS---HTLSALVENLKLRQKNI-----------TAFNETLFRNQLALATWTIQGVANALSG--DIWNIDNEF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99376-1", "uniprot_id": "TFR1_RAT", "id": "Q99376-1", "name": "Transferrin receptor protein 1", "aln": "---MMDQARSAFSNLFGGEPLSYTRFSLARQVDGDNSHVEMKLAAD-EEENADSNMKASVRKP--KRFNG----------RLCFATIAVVIFFLIGFMIGYLGYCKRVEQKEECVRLAEAEEADKSENDETEYVPKSSRLFWADLKTLLSE-KLNSIEFTDIIKQLSQNTYTPREAGSQKDENLAYYIENLFHDFKFSKVWRDEHYVKIQVKNSVSQNLVTIN-SG---SNIDPVEAPEGYVAFSKAGEVTGK-LVHANFGTKKDFEELNY---SVNGSLVIVRAGKITFAEKVANAQSFNAIGVLIYMDRNTFPV--------------VEADLQFFGHAHLGTGDPYTPGFPSFN-HTQFPPSQSSGLPSIPVQTISRAAAEKLFKNMEGN-CPPSWNIDSS-CKLELSQ----------NQNVKLTVNNVLKETR-ILNIFGVIKGYEEPDRYIVVGAQRDAWGPGVA-KSSVGTGLLLKLAQVFSDMISKDGFRPSRSIIFASWTAGDYGAVGATEWLEGYLSSLHLKAFTYINLDKVVLGTS--NFKVSASPLLYTLMGKIMQDVKHPIDGKYLYRDSNWIS------------KIEELSLDNAAFPFLAYSGIPAVSFCFCED------EDYPYLGTKLDTYEILIQKV-PQLNQMVRTAAEVAGQFIIKLTHDIELTLDYEMYNSKLLSFMKDLNQFKADIKD------MGLSLQWLYSARGDYFRATSRLTTDFHNAEK--TNRFVMR---EINDRIMKVEYHFLSPYVSPRESPFRHIFWGSGS---HTLSALVENLRLRQKNI-----------TAFNETLFRNQLALATWTIQGVANALSG--DIWNIDNEF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AB32TIL0-1", "uniprot_id": "A0AB32TIL0_DANRE", "id": "A0AB32TIL0-1", "name": "Transferrin receptor protein 1", "aln": "MAGTIGQAKMKFSRMVNSR--SYSRFNQSQNPDGDGSRVEVKLAVDGEEEEMDGTELGNMQQETYTRSTGRS--EPLNKYRILVCVGAALLVFLVGLLIGYS-VHRKSDNKSEPLETPCSKEIQAEEPDPPQYEPIVPSIDWSDIVKLLND-KLSS---KSIEEQLSVYSQIGRSAGSSVDNKLGDTIHDAFTKLNMEP-WVDEHYVKLQNPDSSNPNKVWFG--------NEEIGSPKGFLAYSETGRREGR-VVYANYGEPADLQAVQANEVSLNGTVVLMRAGRISMAQKVMNVAKLGAVAALIYPDPADY----------------DGMDTELYGHVHLGSGDPYTPGFPSFN-HTQFAPAKSSGLPEILAQTIPASMARKILSKMGGSEVPSKFKGGFT-SYKFGDE----------SNKVALSINNKLVDTK-IHNVFGVIKGYVDPDRYVVIGAQRDSMTSGYA-KSAVGTTLLMELARVFNELK-KEGFKPKRSIVFASWTAGDFGKVGATEWLEGYWASLDRKAFTYISLDGVVSGKD--SLRASASPLLHTLLQKTLEKVKAPMPS----YGSDFSS------------ILTNMQMDDGAYPFLTFSGIPSVSFSFISSRT---TPDYKYFGTEMDTKERLDFVTGQQVVKLSMLAAQVAGQMALRLVHDQILRLDVTKYGGVIESHVKNIINHVNDLKSEKVEKIETLSTEWLIAAKSSYSRAATKLNNDIKNSDL--EDMEMCR---IINNRIMKVEHNFLSPYVSIRDFPFRHIFFGNGW---QTATDLENYLQDVRDKK-----------ASFDIDQVLNKFALLTWSIQGCANDLAG--DIWSLDNEI-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9JKX3-1", "uniprot_id": "TFR2_MOUSE", "id": "Q9JKX3-1", "name": "Transferrin receptor protein 2", "aln": "MEQRWGLLRRVQQWSPRPSQTIYRRVEGPQLEHLEEE--DREEGAELPAQFCPMELKGPEHLGSCPGRSIPIPWAAAGRKAAPYLVLITLLIFTGAFLLGYVAFRGSCQACGDSVLVVDEDVNPE---DSGRTT-----LYWSDLQAMFLR-FLGE---GRMEDTIRLTSLRERVAGSARMATLVQDILDKLSRQKLDHVWTDTHYVGLQFPDPAHANTLHWVDADGSVQEQLPLEDPEVYCPYSATGNATGK-LVYAHYGRSEDLQDLKAKGVELAGSLLLVRVGITSFAQKVAVAQDFGAQGVLIYPDPSDFSQDPHKPG--------LSSHQAVYGHVHLGTGDPYTPGFPSFN-QTQFPPVESSGLPSIPAQPISADIADQLLRKLTGPVAPQEWKGHLSGSPYRLGP----------GPDLRLVVNNHRVSTP-ISNIFACIEGFAEPDHYVVIGAQRDAWGPGAA-KSAVGTAILLELVRTFSSMV-SNGFRPRRSLLFISWDGGDFGSVGATEWLEGYLSVLHLKAVVYVSLDNSVLGDG--KFHAKTSPLLVSLIENILKQVDSPNHSGQTLYEQVALTHPSWD-----AEVIQPLPMDSSAYSFTAFAGVPAVEFSFMED-----DRVYPFLHTKEDTYENLHKMLRGRLPAVVQAVAQLAGQLLIRLSHDHLLPLDFGRYGDVVLRHIGNLNEFSGDLKE------RGLTLQWVYSARGDYIRAAEKLRKEIYSSER--NDERLMR---MYNVRIMRVEFYFLSQYVSPADSPFRHIFLGQGD---HTLGALVDHLRMLRADGSGAASSRLTAGLGFQESRFRRQLALLTWTLQGAANALSG--DVWNIDNNF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UP52-1", "uniprot_id": "TFR2_HUMAN", "id": "Q9UP52-1", "name": "Transferrin receptor protein 2", "aln": "MERLWGLFQRAQQLSPRSSQTVYQRVEGPRKGHLEEEEEDGEEGAETLAHFCPMELRGPEPLGSRPRQPNLIPWAAAGRRAAPYLVLTALLIFTGAFLLGYVAFRGSCQACGDSVLVVSEDVNYEPDLDFHQGR-----LYWSDLQAMFLQ-FLGE---GRLEDTIRQTSLRERVAGSAGMAALTQDIRAALSRQKLDHVWTDTHYVGLQFPDPAHPNTLHWVDEAGKVGEQLPLEDPDVYCPYSAIGNVTGE-LVYAHYGRPEDLQDLRARGVDPVGRLLLVRVGVISFAQKVTNAQDFGAQGVLIYPEPADFSQDPPKPS--------LSSQQAVYGHVHLGTGDPYTPGFPSFN-QTQFPPVASSGLPSIPAQPISADIASRLLRKLKGPVAPQEWQGSLLGSPYHLGP----------GPRLRLVVNNHRTSTP-INNIFGCIEGRSEPDHYVVIGAQRDAWGPGAA-KSAVGTAILLELVRTFSSMV-SNGFRPRRSLLFISWDGGDFGSVGSTEWLEGYLSVLHLKAVVYVSLDNAVLGDD--KFHAKTSPLLTSLIESVLKQVDSPNHSGQTLYEQVVFTNPSWD-----AEVIRPLPMDSSAYSFTAFVGVPAVEFSFMED-----DQAYPFLHTKEDTYENLHKVLQGRLPAVAQAVAQLAGQLLIRLSHDRLLPLDFGRYGDVVLRHIGNLNEFSGDLKA------RGLTLQWVYSARGDYIRAAEKLRQEIYSSEE--RDERLTR---MYNVRIMRVEFYFLSQYVSPADSPFRHIFMGRGD---HTLGALLDHLRLLRSNSSGTPG--ATSSTGFQESRFRRQLALLTWTLQGAANALSG--DVWNIDNNF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UQQ1-1", "uniprot_id": "NALDL_HUMAN", "id": "Q9UQQ1-1", "name": "Aminopeptidase NAALADL1", "aln": "--------------------MQWTKVLG--------------------------------------------------------LGLGAAALLGLGIILGHFAIPKKANSLAPQDLDLEILETVMGQLDAHRIR--------ENLRELSREPHLASSPRDEDLVQLLLQRWKDPESGLDSAEASTYEVLLSFPSQ------EQPNVVDIVGPTGGIIHSCHRTEEN-VTGEQGGPDVVQPYAAYAPSGTPQGL-LVYANRGAEEDFKELQTQGIKLEGTIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETFPNSWYLPPSGVERGSYYEYFGDPLTPYLPAVPSSFRVDLANVSGFPPIPTQPIGFQDARDLLCNLNGTLAPATWQGALG-CHYRLGPGFRPDGDFPADSQVNVSVYNRLELRN-SSNVLGIIRGAVEPDRYVLYGNHRDSWVHGAV-DPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGLIGSTEFTEEFFNKLQERTVAYINVDISVFANA--TLRVQGTPPVQSVVFSATKEIRSPGPGDLSIYDNWIRYFNRSSPVYGLVPSLGSLGAGSDYAPFVHFLGISSMDIAYTYDRSKTSARIYPTYHTAFDTFDYVDKFLDPGFS-SHQAVARTAGSVILRLSDSFFLPLKVSDYSETLRSFLQAAQQDLGALLEQ-----HSISLGPLVTAVEKFEAEAAALGQRISTLQKGSPDPLQVR---MLNDQLMLLERTFLNPRAFPEERYYSHVLWAPRTGSVVTFPGLSNACSRARDTAS----------GSEAWAEVQRQLSIVVTALEGAAATLR---PVADL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08919-1", "uniprot_id": "TRE1_YEAST", "id": "Q08919-1", "name": "Uncharacterized protein TRE1", "aln": "MVNTRGYTTLPNVEEPANNSQDELNSQDFEQAIGMPSEPPVYVEEMGMEEPQAPEAFSEKVQRFRMCFENNVVIPVKKNVVDPLAQMISLASEKFDLFLSKIGNVMVMRRIFYIMMMSIIAALIIASDRLPNGKARGSNGSFSDHDLLLQY-ARKSIDLSKIERDLEYISSMPHMSGTSGDAAIRHYIKESFDKNGIRLAGEEEFMAYSNYPGNVSLRVYSKDDTEG----FDIPLNEENFNPMSHNGQLNNIPVIYANKASLDDMASMQDQGLLNGDFILLVHYGDYVFQQMLT-AQEYGAKAIIFISEPYQDNK--------------DVIQMKSVALPQYGTGDALTPEWEGSI-RDPIDATEAKCLPKIPSIPISANQGDKILAILSDTGVKFSNNLFSG----SLND-----------CRLDLLVQTAIRERHPVHDIVGKIEGSEQAGRAIVIAAPRNSASYGTM-YPSFGTVVLLSLIQLYQEMVYKFDWKPLRNIYFISFGGSEFNEAGATELMEKRTEALKSEIYTIIDVGQIGIWDDSNNLEIQCHPLLVDLFQKNMTSRKFNVKVDN------------------------VHQFGDWTPYLAQGIPVAIISSPGVMN------REHPIYTVEDKFDFIKDKLRDKKKGEVLSEIMLYLVEKSLELIDDPFIPFSISNYVDFLSTTLKDLQKECPDTVN---FDEVFLGTTLWENTKLQFEKWKSEWTELMYGAGTYIEPTIIAINRWSWNYLLSLIGVTQCLEEGLMDRTFYKNVIFGPKLWVDKGDPLRSWTFPEIRDTIA-----------IKDWSSVQVQANTLGTILQNTARYFLENKNLHGINTNEF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: . . : : . : :* : : : . . . : . : . :::*: . *: : . : : : * . . .. . :. : . **. ** . . . :* * .* . :: : . : . : : : . ::.. *.* :..: :: . *:: * .: ** :*:.* : : . ::* *.: * *: . ::. *:** * *. . . :.:. .:. . * : :. . . .. : :. :. . : . . . :.* .. : :. * : : : : : .: : * : : : ::: . : . : ::. * : : .: ", "identical_positions": 33, "similar_positions": 149, "identity": "3.82%" }, { "cls_id": "homologset.agr.SGD:S000006098", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A2T5-1", "uniprot_id": "D4A2T5_RAT", "id": "D4A2T5-1", "name": "", "aln": "----------MAQ-RYDELPHYGGMDGVGVPASMYGDPHAPRP----IPPVHHLNHGPPLHATQHYG----------AHAPHPNVMPAS--MGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVA------GGDVCSSDSFNEDIAVFAK-QVRAEKPLFSSNPELDNLMIQAIQVLRFHLL----------------------------ELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDG------------------------SSKSDHEELSGSSTNLADHN------------PSSWRDHDDATSTHSAGTPGPSS------------GGHAS------------------------QSGDNS-----------------SEQGDGLDNSVASPGT-GDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPS--------------------VSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGLQSMPGDYVSQGGPVGMGMAQPSYTPPQMTPHPTQLRHGPPMHSYLPSHPHHPAMMMHGGPPTHPGMTMSAQSPTMLNSVDPNVGGQVMDIHAQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97367-1", "uniprot_id": "MEIS2_MOUSE", "id": "P97367-1", "name": "Homeobox protein Meis2", "aln": "----------MAQ-RYDELPHYGGMDGVGVPASMYGDPHAPRP----IPPVHHLNHGPPLHATQHYG----------AHAPHPNVMPAS--MGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVA------GGDVCSSDSFNEDIAVFAK-QVRAEKPLFSSNPELDNLMIQAIQVLRFHLL----------------------------ELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDG------------------------SSKSDHEELSGSSTNLADHN------------PSSWRDHDDATSTHSAGTPGPSS------------GGHAS------------------------QSGDNS-----------------SEQGDGLDNSVASPGT-GDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPS--------------------VSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGLQSMPGDYVSQGGPMGMGMAQPSYTPPQMTPHPTQLRHGPPMHSYLPSHPHHPAMVMHGGPPTHPGMTMSAQSPTMLNSVDPNVGGQVMDIHAQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3AK57-1", "uniprot_id": "A0A8M3AK57_DANRE", "id": "A0A8M3AK57-1", "name": "", "aln": "----------MAQ-RYDELAHYGGMDGVG----MYGDPHAPRP----LPQVHHLNHGPPLHASQHYG----------THAPHPNVMPTS--MGSAVNDVLKRDKDQIYGHPLFPLLALVFEKCELATCTPREPGVA------GGDVCSSDSFNEDIAVFAK-QVRAEKPLFSSNPELDNLMIQAIQVLRFHLL----------------------------ELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDG------------------------SSKSDHEELSGSSTNLADHMGNGWIRSDRLQNPASWRDHDDATSTHSAGTPGPSS------------GGLAS------------------------QSGDNS-----------------SEQGDGLDNSVASPGT-GDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPS--------------------VSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGPMS------------GMGMN----------------------------------------------MGMDGQWHYM----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6GI80-1", "uniprot_id": "A0A8I6GI80_RAT", "id": "A0A8I6GI80-1", "name": "", "aln": "----------MAQ-RYDDLPHYGGMDGVGIPSTMYGDPHAARS----MQPVHHLNHGPPLHSHQYP------------HTAHTNAMAPS--MGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPGVA------GGDVCSSESFNEDIAVFAK-QIRAEKPLFSSNPELDNLMIQAIQVLRFHLL----------------------------ELEKVHELCDNFCHRYISCLKGKMPIDLVIDDREG------------------------GSKSDSEDVTR-AANLTDQP-------------SWNRDHDDTASTRSGGTPGPSS------------GGHTS------------------------HSGDNS-----------------SEQGDGLDNSVASPST-GDDDDPDKDKKRHKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGKSPLVTVFKSGKRKPTSSHSPGGLLPVSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGLQSMPGEYVARGGPMGVSMGQPSYTQAQMPPHPAQLRHGPPMHTYIPGHPHHPAVMMHGGQP-HPGMPMSASSPSVLNTGDPTMSGQVMNIHAQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60954-1", "uniprot_id": "MEIS1_MOUSE", "id": "Q60954-1", "name": "Homeobox protein Meis1", "aln": "----------MAQ-RYDDLPHYGGMDGVGIPSTMYGDPHAARS----MQPVHHLNHGPPLHSHQYP------------HTAHTNAMAPS--MGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPGVA------GGDVCSSESFNEDIAVFAK-QIRAEKPLFSSNPELDNLMIQAIQVLRFHLL----------------------------ELEKVHELCDNFCHRYISCLKGKMPIDLVIDDREG------------------------GSKSDSEDVTR-SANLTDQP-------------SWNRDHDDTASTRSGGTPGPSS------------GGHTS------------------------HSGDNS-----------------SEQGDGLDNSVASPST-GDDDDPDKDKKRHKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRA---------------------------VSQGTPYNPDGQPMGGFVMDGQQHMGIRAPG--PMSG--------MGMNMG---------------------------------------------------------------MEGQWHYM-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8K0S8-1", "uniprot_id": "ME3L2_HUMAN", "id": "A8K0S8-1", "name": "Putative homeobox protein Meis3-like 2", "aln": "----------MAR-RYDELPHYPSIADGPAALAGFPEAVP-------AAPGPYGPHRP------------------------PQPLPPG--LDS---DGLKRDKDEIYGHPLFPLLALVFEKCELATCSPRDGAGAGLGTPRGGDVCSSDSFNEDNTAFAK-QVRSERPFFSSNPELDNLMIQAIQVLRFHLL----------------------------ELE-----------------KGKMPIDLVIEDRDG------------------------GCREDFEDYPASCLSLPDQN------------NIWIRDHEDSGSVHLG-TPGPSS------------GGLAS------------------------QSGDNS-----------------SDQGVGLDTSVASPSSGGEDEDLDQEPRRNKKRGIFPKVATNIMRAWLFQHLWHPYPSEEQKKQLVQDTGLTILQVNNWFINARRRMVQPMIDQSNRIG----------------------------QGAAFSPEGQPIGGYTET-EPHVAFRPPAS-------------VGMSLN---------------------------------------------------------------LEGEWHYL-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97368-1", "uniprot_id": "MEIS3_MOUSE", "id": "P97368-1", "name": "Homeobox protein Meis3", "aln": "----------MAR-RYDELRHYPGITEHTTALASFSEAAPSVP----RAPGPYTPHRP------------------------PQLQAPG--LDS---DSLKREKDDIYGHPLFPLLALVFEKCELATCSPRDGASAGLGSPPGGDVCSSDSFNEDIAAFAK-QIRSERPLFSSNPELDNLMVQAIQVLRFHLL----------------------------ELEKVHDLCDNFCHRYITCLKGKMPIDLVIEDRDG------------------------SCREDLEDYAASCPSLPDQN------------TTWIRDHEDSGSVHLG-TPGPSS------------GGLAS------------------------QSGDNS-----------------SDQGDGLDTSVASPSSAGEDEDLDLERRRNKKRGIFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRTG----------------------------QGASFNPEGQPMAGFTET-QPQVTVRTPGS-------------MGMNLN---------------------------------------------------------------LEGEWHYL-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O46339-1", "uniprot_id": "HTH_DROME", "id": "O46339-1", "name": "Homeobox protein homothorax", "aln": "----------MAQPRYDDGLHGYGMDSGAAAAAMYDPHAGHRPPGLQGLPSHHSPHMTHAAAAAATVGMHGYHSGAGGHGTPSHVSPVGNHLMGAIPEVHKRDKDAIYEHPLFPLLALIFEKCELATCTPREPGVQ------GGDVCSSESFNEDIAMFSK-QIRSQKPYYTADPEVDSLMVQAIQVLRFHLL----------------------------ELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDTTKP------------------PELGSANGEGRSNADSTSHTDGASTPDVRPPSSSLSYGGAMNDDARSPGAGSTPGPLSQQPPALDTSDPDGKFLSSLNPSELTYDGRWCRREWSSPADARNADASRRLYSSVFLGSPDNFGTSASGDASNASIGSGEGTGEEDDDASGKKNQKKRGIFPKVATNILRAWLFQHLTHPYPSEDQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVY--------------------------TPHPGPSGYGHDAMGYMMDSQAHMMHRPPGD-------------PGFHQG-----------------------------------------------------------YPHYPPAEYYGQHL-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M3B5L4-1", "uniprot_id": "A0A8M3B5L4_DANRE", "id": "A0A8M3B5L4-1", "name": "", "aln": "---------MMAAQSVSIDKYPEGDQQMQVMEQSENDLKKGFS--------------------------------------NGNTGNSSSPVSNEPQTQMDIDKACIYRHPLFPLLALLFEKCEQSTLG--------------SDCVTSASFDVDIENFVRSQEKDGKAFFSEDPDLDNLMVKAIQVLRIHLL----------------------------ELEKVSDLCKDFCSRYISCLKAKMNSETLLSGDPGS-----------------------PYSPVHDQLSNPFSGPLSPQSLLIPSSGLQQGSVTVTTVNPSQVATGNTVYQPVTVVTP-------QGQVVT------------------------QAISPG---------------ALHIQNSQLQLQLNQDLSFFGGDDSSP----KNKRGVLPKQATNVMRSWLFQHIAHPYPTEEEKKQIATQTNLTLLQVNNWFINARRRILQPMLDANSTEAS---------------------------KSKKKVAQSRPLHRFWSDSIASTGSQQQLTMPDGSLVTVGMNVDGFQALSSDGATLAMQQVLMG--------------------------NHSEDETDESGNEDDTDMSTANMPGLGLDVSD-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z916-1", "uniprot_id": "A1Z916_DROME", "id": "A1Z916-1", "name": "", "aln": "MISPEQEEVNMVLDRHVRQNIQDMMHEAHVQASLLENEGRGRF-------HSDSSLDQDSLHADVIVEEDQSTEHGANQVQNYHDMMVDSEHHIDINGSLRKRRGNLPKTSVKILKRWLYEHRYNAYPSDAE------------KFTLSQEANLTVLQVCNWFINARRRILPEMIRREGNDPLHFTISRRGKKVSPNCSRSSALGANLTGPNPAHGSPASEVVVGATEEVDGAGEIHEGIANVLTNFEQYVQGPNGQMVKMEPEYEDSVIYSWQQAIANNPMGFQSLHSSLQATMIDKIK--------------NYQMRKAAAIGGSAVGSGGAGGSSSNSSPATSILPYSLF-----------------------GQLPPE----------------FDDEEKPRPPKRVRTRTVAAKSPRENAKQAKQKTGNKQETMYCYKDSYGGIVVSPRSEGEESAQGYESCGPNSEEEVRFETSHDWQSVIKTVFGTEEVSTS--------------------------AGNNPGTSGSKGSVQNTAIWNRNQTAKRDVNQQLTDFESELNRIQASEIQTIDPTNSNQQDIGDNLQADEVFTGAEAEAGQSQLSAMSQGTSPDERAKYKCLYYLVETAMAVRQNDDVQDDDFVYMGD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z913-1", "uniprot_id": "A1Z913_DROME", "id": "A1Z913-1", "name": "", "aln": "MISPEQEEVNMVLDRHVRQNIKDLMHEAHVHASLLNNEGRDRF-------HSDSSLDQDSLHA--VVGNDLSTEQGANQVQNYHDMMVDSEHHVDINGSLRKRRGNLPKSSVKILKRWLYEHRYNAYPSDAE------------KFTLSQEANLTVLQVCNWFINARRRILPEMIRREGNDPLHFTISRRGKK-----------------------------VVGATEEVDGAGEIHEGIANVLTNFEQYVQGPNGQMVKMEPEYEDSVIYSWQQAIANNPMGFQSLHSSLQATMIDKIK--------------NYQMRKAAAIGGSAVGSGGAGGSSSNSSPATSILPYSLF-----------------------GQLPPE----------------FDDEEKPRPPKRVRTRTVAAKSPRENAKQAKQKTGNKQETMYCYKDSYGGIVVSPRSEGEESAQGYESCGPNSEEEVRFETSHDWQSVIKTVFGTEEVSTS--------------------------AGNNPGTSGSKASVQNTAIWNRNQTAKRDVNQQLTDFESELNIIQASEIQTIDPTNSNQQDIGDNLQADEVFTGAEAEAGQSQLSALSQGTSSDEEGKYKCLYYLVETAMAVRQNDDVQDDDFVYMGD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9GZN2-1", "uniprot_id": "TGIF2_HUMAN", "id": "Q9GZN2-1", "name": "Homeobox protein TGIF2", "aln": "--------------------------------------------------MSDSDLGED------------------------EGLLS--------LAGKRKRRGNLPKESVKILRDWLYLHRYNAYPSEQE------------KLSLSGQTNLSVLQICNWFINARRRLLPDMLRKDGKDPNQFTISRRGGK-----------------------------ASDVALPRGSS----------PSVLAVSVPAPTN-------------------------------VLSLSVCSMP---------------------------LHSGQGEKPAA-------------PFPRG-----------------------ELESP---------------------KPLVTPG--STLTLLTRAEAG------SPTGG-------------------------------------------------------LFNTPPPTPP--------------------------EQDKEDFSSFQLLVEVALQRAAEMELQKQQDPSLPLLHTPIPLVSENPQ-------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZTL5-1", "uniprot_id": "A0A8I5ZTL5_RAT", "id": "A0A8I5ZTL5-1", "name": "", "aln": "--------MTLLLG---SATLERGTGDLGPRTRAVQLEGVVAA-------ASGSDSEDE------------------------DSMDSPLDLSSSAASGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQE------------KALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFTISRRGAK-----------------------------ISEASSIEAAMGIKNFMPTLEESPFHSCVVGPNP-------------------------------TLGRPVSPKPPSP--------------GPILARPSVICHTTVTALKDG-------------PFSLC-----------------------QAVSVG----------------HSTDVQQVAPSNFTDASLRYPEDTCKSGPSPNPQSG-------------------------------------------------------LFNTPPPTPP--------------------------DLN-QDFSGFQLLVDVALKQAAEMELQAKLTA------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IUE1-1", "uniprot_id": "TF2LX_HUMAN", "id": "Q8IUE1-1", "name": "Homeobox protein TGIF2LX", "aln": "-----------------MEAAADGPAETQSPVEKDSPAKTQSP-------AQDTSIMSR--------------------------NNADTGRVLALPEHKKKRKGNLPAESVKILRDWMYKHRFKAYPSEEE------------KQMLSEKTNLSLLQISNWFINARRRILPDMLQQRRNDPIIGHKTGKDAH-----------------------------ATHLQSTEASVP------------AKSGPSGPDN-------------------------------VQSLPLWPLPKG-------------------------------------------------QMSRE-----------------------KQPDPE----------------SAPSQKLTGIAQPKKKVKVS------------VTSP----------------------------------------------------------SSPELVS--------------------------PEEHADFSSFLLLVDAAVQRAAELELEKKQEPNP----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41817-1", "uniprot_id": "CUP9_YEAST", "id": "P41817-1", "name": "Homeobox protein CUP9", "aln": "-------------MNYNCEIQNRNSKNVDNQVSLPPIQVLFNS----------------------------------------IEKRSMPELAFSNIEYSHGNLRSSTEEQNYPAPVLLPQHHSIAYPAINSGGTS--------TTATPTASTVETSKTSSSAMDTQSQYGSSKKSKSASDDAKPCYKSAPIY---------------------------EIINKEKDAGAQYNRPFSDFVESKSRRKQNSGRRSN------------------------LPKETVQILNTWLLNHLNNP-------------YPTQQEKRELLIKTGLTKIQLS------------NWFIN-----------------------------------------------VRRRKIFSDYYTLVNSIPNDNANNTPVERVQNVSAYHNTLSATN--------------------------------------------NTMYDATSTCST------------------------DYELSKRFAHAPVTRRKKLIDRLEELKKLSNPDMN-----------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . . . ", "identical_positions": 0, "similar_positions": 6, "identity": "0.0%" }, { "cls_id": "homologset.agr.SGD:S000006099", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC40-1", "uniprot_id": "NCBP2_RAT", "id": "B1WC40-1", "name": "Nuclear cap-binding protein subunit 2", "aln": "MSGGLLKALRSDSYVELSEYRDQHFRGDNEEQEKLLKK------SCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYREDYDAGRGGYGKLAQKQ----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ49-1", "uniprot_id": "NCBP2_MOUSE", "id": "Q9CQ49-1", "name": "Nuclear cap-binding protein subunit 2", "aln": "MSGGLLKALRSDSYVELSEYRDQHFRGDNEEQEKLLKK------SCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYREDYDAGRGGYGKLAQKQ----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52298-1", "uniprot_id": "NCBP2_HUMAN", "id": "P52298-1", "name": "Nuclear cap-binding protein subunit 2", "aln": "MSGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKK------SCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JGR6-1", "uniprot_id": "NCBP2_DANRE", "id": "Q8JGR6-1", "name": "Nuclear cap-binding protein subunit 2", "aln": "MS-IKLNALFSDSYVDVSQYRDQHFKGNRYEQEKLLKQ------SATLYVGNLSFYTTEEQVHELFAKCGDVKRIIIGLDKIKKTACGFCFVEYYTRADAENAMRFVNGTRLDDRIIRTDWDAGFKEGRQYGRGKSGGQVRDEYRQDYDPARGGYGKMVQKS----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3L6-1", "uniprot_id": "NCBP2_DROME", "id": "Q9V3L6-1", "name": "Nuclear cap-binding protein subunit 2", "aln": "--------MFAS--VELSSYRDQHFKGSRSEQERSLRD------SCTLYVGNLSFYTTEEQIHELFSRCGDVRVIVMGLDKYKKTPCGFCFVEYYVRSEAEAAMRFVNGTRLDDRLIRVDWDAGFVEGRQYGRGKTGGQVRDEYRTDYDAGRGGYGKLLSQKI------------APNTDNR--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A6PVI3-1", "uniprot_id": "NCB2L_HUMAN", "id": "A6PVI3-1", "name": "Nuclear cap-binding protein subunit 2-like", "aln": "MS-KDLKILCKDPALELSCYRDHQFSGRKFQQEKLLKE------SSTLNMGNLSFYTTEEKIHELFSRS-DIRNIFMGLDKIKKTACGFCFVECHNRADAENAMRFLTGTCLDEWIICTDWDVGFREGQQYGRGKSGGQVRDEFREDFHSGRGGFGRQTQI-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08920-1", "uniprot_id": "NCBP2_YEAST", "id": "Q08920-1", "name": "Nuclear cap-binding protein subunit 2", "aln": "MSLEEFDEVKYDHSTKRLDTPSRYLLRKARRNPNGLQELRESMKSSTIYVGNLSFYTSEEQIYELFSKCGTIKRIIMGLDRFKFTPCGFCFIIYSCPDEALNALKYLSDTKLDEKTITIDLDPGFEDGRQFGRGKSGGQVSDELRFDFDASRGGFAIPFAERVGVPHSRFDNSSSQSNTNNYIPPPDAMGTFRPGFDEEREDDNYVPQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . .: : .: . *:. *.*: :*******:**:::***::. :: *.:***: * *.*****: :* *::::..* **: * * * ** :*:*:***::**** ** * *:...***:. ", "identical_positions": 52, "similar_positions": 47, "identity": "25.0%" }, { "cls_id": "homologset.agr.SGD:S000006100", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P11612-1", "uniprot_id": "PPY_DROME", "id": "P11612-1", "name": "Serine/threonine-protein phosphatase PP-Y", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAVLTT-----------------------------------------------------HEIDCIIKELTSL----------NGSECTLKEELIERLIQQTREVIKWQPMLLELQAPVNICGDIHGQFTDLLRIFKACGFPPKANYLFLGDYVDRGKQSLETICLLFAYKVKYPLNFFLLRGNHESASINKIYGFYDEIKRRHTVRLWHSFTDCFNWLPVAALVGERIFCCHGGLSPSLRNLQQINHIQRPTDIPDEGIMCDLLWADLNHTTKGWGHNDRGVSFTFDKVIVRDFLKAFDLQLMVRAHEVVEDGYEFFANRQLVTVFSAPNYCGMMNNAGGVMSVSTDLICSFVIILP---------CHKYKMIATDANQMPTNEEE----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2A5-1", "uniprot_id": "Q9W2A5_DROME", "id": "Q9W2A5-1", "name": "Serine/threonine-protein phosphatase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRRSTVLSTGKESSKEEK-----------------------------------------NRMSQLDVIIGQLKTMA-------VGNRRAGNLSEATITYICQASRELFLSQPMLLELSAPVKICGDLHGQFKDLLRIFQQCGVPPLSNYLFLGDYVDRGHCSIETLSLLLTYKLRYPETFFLLRGNHESADLNRVYGFFDECKRRYSIKLWRSFVDCYDCMPVAAIIADRIFCVHGGLSPDLNNLDDIRRLNRPTDVPSDGLLCDLLWSDPDETTGTWASNDRGVSFTFGANIVEGFLMQHKFNLIVRAHQVVEDGYEFFADRQLVTIFSAPNYCDIFDNCGAVLVVDAKLVCHFVIIRPRPFSRPTGFESDSGSTATATNGPPPSMREKRLY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32945-1", "uniprot_id": "PPQ1_YEAST", "id": "P32945-1", "name": "Serine/threonine-protein phosphatase PPQ", "aln": "MRRSPSRSNNNFAVPNCSTNSNSSQQQLTTPSDDLNSNEPNDPDDSRSLPTIKKFNNKHSINNYNTLASAGKNNNNKRASNDNLLIPGENAHKQKIYTKDENLKSLYLDIDVSVAKALSSSATAPKLINTARTSSTTTATTSNNILTSPSYRESNYSSPSSYSFSSYYSSATSASSSTSSFLKSSGLSSRVKSPSSSVKAGSFGAPSSPTSGIPNPKSSKKPIFLRRYSHDTSSNEGLDIDVAIEKLLQVGESREITKTSKKKNFPFHSWEIQLICYHAREIFLNQPTLLRLQAPIKVVGDVHGQFNDLLRILKLSGVPSDTNYLFLGDYVDRGKNSLETILLLLCYKIKYKDNFFMLRGNHESANVTKMYGFYDECKRRLSSKVWKMFVDVFNTLPLAAIIQDKIFCVHGGISPDLHDMKQIEKVARPTDIPESGLVTDLLWSDPDPQVTDWSENDRGVSYTFSKRNVLDFCAKFKFDLILRGHMVVEDGYEFFARKKFVTIFSAPNYCGEFHNWGAVMSVTTGMMCSFELLKP-------------RALKNKKKLYKTKV------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.*.: ::* * :* : : : . * : :**:: ** **.*.**::: **:****.*****:: .*.*. :************: *:**: **: **::* .**:********.:.::***:** *** : ::*: *.* :: :*:**:: ::*** ***:**.*.::.:*.:: ****:*..*:: ****:* : . *. ******:**. * .* ..::*::*.* ********** :::**:*******. :.* *.*: * : ::* * :: * . : .. ", "identical_positions": 132, "similar_positions": 102, "identity": "23.24%" }, { "cls_id": "homologset.agr.SGD:S000006102", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CCJ9-6", "uniprot_id": "P20L1_MOUSE", "id": "Q8CCJ9-6", "name": "PHD finger protein 20-like protein 1", "aln": "MSKKPPNRPGITFEIGARLEALDYLQKWYPSRIEKIDYEEGKMLVHFERWSHRYDEWIYWDSNRLRPLERPALRKEGLKDE-------------------------------EELFDFKAGEEVLARWTDCRYYPAKIEAINKEGTFTVQFYDGVIRCLKRMHIKAMPEDAK----GQVKSQHPLSWCCPID-------PAGSCNQSMGSEDWIALVK-------AAAAAAAKNKTGTKPRASANSNKEKERDGGK-------------WFKLPSKKAETSTCIVTAEIEK-----KEELPTSSETFGLHIDTVPKIVFPQP-------ESTLTNKRKNNQGN--SFQAKRARLNKITGLLASKAVGVDGAERKEDCSATAPVLEQ----AISPKPQSQKKNEAVISSSANTQKPA----LLS---------------------STLSSGKARSKKCKHESGESSGCIKTPKSPLAP-----ELIQAKDLTLVSQLSSVINKTSSPQPVNPPRPCKHS-----ERRRRSQRLAT-------------------------LPMPDDSLEKLSSSSSATDGKAFS--------ISSQNQQQSSVPEVPAIAYVPLQKLGPCLP-----LDLSCGSEVTGSRTPHPSYHGGECPREEKEE---TPLFANPTSKVVSDVKGAAAATGISKTEKKVKLEEKTSTAFGKRKEKDKEKKEKRDKDHYKPKQKKKKKKKKKSKQHDYSDYEDSSLDFLERCSSPLTRSSGSSLAPRSTFTEKTTTYQYPRAILSVDLSGENLSDVEFLDDSSTESLLLSGDEYNQDFDSTNFEESQDEDD---ALNEIVRCICELDEENGFMIQCEECLCWQHSVCMGLLEDSIPEQYICYICRDPP-------GQRWSAKYRYDKEWLNNGRMYGLSFLKENYSHLNAKKIVSTHHLLADVYGVTEVLHGLQLKIGILKNKHHPDLHLWAYSGKRKDQDQAVAEA---------ERKITPQDRANSEGKECVQNHKEPALRMEETYITSEHSYQKPQSFSQDCQSLTDPGSSDDDDASSFEEDGELRVPDKSHLLY--KNRGVSEKNPASGNKVFVYNDKKGTEGPGDS----------------------------HLQWQLNLLTHIENVQNEVTSRMDLIEKEVDVLESWLDFTGELEPPDPLARLPQLKRHLKQLLLDVGKVQQIATLCSV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V9H5-1", "uniprot_id": "P20L1_RAT", "id": "Q4V9H5-1", "name": "PHD finger protein 20-like protein 1", "aln": "MSKKPPNRPGITFEIGARLEALDYLQKWYPSRIEKIDYEEGKMLVHFERWSHRYDEWIYWDSNRLRPLERPSLRKEGLKDE-------------------------------EDLFDFKAGEEVLARWTDCRYYPAKIEAINKEGTFTVQFYDGVIRCLKRMHIKAMPEDAK----GQVKSQHPLSWCCPID-------PAGSCNQSMGSEDWIALVK-------AAAAAAAKNKTGSKPRTSANSNKEKERDGGK-------------WFKVPSKKAETSTCIVTAEIEK-----KEELPTSSEPFGLHIDSVPKIVFPQP-------ESTLTNKRKNNQGN--SFQAKRARLNKITGLLASKAVGVDGAEKKEDCSATAPVLEQ----AISPKPQSQKKNEAVISSSANTQKPA----LLS---------------------STLSSGKARSKKCKHESGESSGCIKAPKSPLAP-----ELIQAKDLTLVSQLSSVINKTSSPQPVNPPRPCKHS-----ERRRRSQRLAT-------------------------LPMPDDSLEKLSSSSSATDGKVFS--------ISSQNQQESSVPEVPAIAYVPLQKLGPCLP-----LDLSCGSEVTGSQAPDSSYPGGECPREEKEE---TPLFANPTSKVVSDVKGAAAATGILKTEKKVKLEEKTSTAFGKRKEKDKERKEKRDKDHYKPKQKKKKKKKKKSKQHDYSDYEDSSLDFLERCSSPLTRSSGSSLAPRSTFTEKTTTYQYPRAILSVDLSGENLSDVEFLDDSSTESLLLSGDEYNQDFDSTNFEESQDEDD---ALNEIVRCICELDEENGFMIQCEECLCWQHSVCMGLLEDSIPEQYICYICRDPP-------GQRWNAKYRYDKEWLNNGRMYGLSFVKENYSHLNAKKIVSTHHLLADVYGITEVLHGLQLKIGILKNKHHPDLRLWAYSGKRKDQDQVVAGA---------ERKVILQDTANSEGRKYVQNHKEPPLKMEETYITSEHSYQKPQSFSQDCHSLTDPGSSDDDDVSSFEEDGELHVADNSHLLYSVKERGVSEKNPASENKVFVYNDKKGMEGPGDA----------------------------HLQWQLNLLTHIENVQNEVTSRMDLIEKEVDVLESWLDFTGELEPPDPLARLPQLKRHIKQLLLDMGKVQQIATLCSV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9PN27-1", "uniprot_id": "A0A8M9PN27_DANRE", "id": "A0A8M9PN27-1", "name": "PHD finger protein 20-like protein 1", "aln": "MSKKTPNRPGITFEVGARVEAQDYLQKWYPSRIEKIDYDEGKMLVHFDRWSHRYDEWILWDSNRLRPLERPALRKEGLKEEEVSERLSEMRASRLRELPGSTESTEDQKDLPQQRQELRDGEEVLARWTDCRYYPAKIESINKEGTYTVQFYDGVIRCVKRIHIKSMPEDAK----GQQDWIALVKAASAAAKNKGGNRPRTSANSNKDREDRREQRSDEEEDDDDADEDDDDDEDDDEEEEDSESEKLADLDSEEEDSKPPAEELESAIAKRRSKRQGNPCSIKRSRLGKGAGCADTETELKAETKELPVTPQQKVPSPEPSPADEKSQSVSAQKTTPSLSNPPACKARSRRLKHDSGESASSCQNTPAAPESSPLPSPTQTLPDSTHTAPSSSPQRRRRSQRLATTSDLICPPS----PHTRDTATHPTPPPDGPLIADEDSSTLVKTEAISQKPVSESPSTATSTASAQAPITEKEKMNDVLPSNQAALEGNSPAVVPAAIQKVPSRTPKANKHAREPIINTKRSDDPLAPNECIIDLDHNKFKCKVSGCSKAFRKAKLLDYHLKYYHNTEKEMDTEVCSPEREGRTRATSASMPTSTLSDVPDNKRRRTVSTSSSLSSQGFMLQMDSGGCVRPSKFCKKKRSSASMSSDSTEVSLPPPTFDNLHDKIIKKDKHLDGLC--IKTERKFKLDDKCQLFVKKR---DKDRRDRKEKDLFRIKQKKKKKKKKKSKLHCYPDLDEMSLAYLERPSSPPHRSSSS--------AFKHSTFQYPRAILSVDLTGENLSDIDFLEDSTTESLLFSGDEYNQDLDSITMEDFQDEDDD--GADEIVRCICEMDEENGFMIQCEECMCWQHSVCMGLLEDSIPEQYICYICRDPP-------GQRWSAKYRHDKDWLQKGHMYGLSFLTENYSHQNAKKIVSTHQLLADVYSVKNLLHGLQLKMDILQNKHNPSLHLWARSWVNSDEDQPMGGV---------PDGLHFKEHLN-------QNSNP------ETYITSEHSYQKP----------PGTGAEHTRDEQGMQMGSQFNIKEE----------EVSSAIALSG----CVNDS-SVEQTRN-----------------------------CLQWQMNLLTHIEDIQNQLSGRMDLIEKELDVLESWLDFTGELEPPDPLARLPQLKCRIKQLLTDLGKVQQMSTLCSV-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9QDM8-1", "uniprot_id": "A0A8M9QDM8_DANRE", "id": "A0A8M9QDM8-1", "name": "", "aln": "MSKRPPNRRGIKFEVGASLEARDSLKNWYVANIEKIDYEDEKVLVHYRQWSHRYDEWFDWASPYLRPVERVQLRREARQDD-------------------------------SFIPGFHVNDRVLASWSDCRFYPAKVLAVNKDASYTVKFYDGVVQTVKGIHVKPFTKER------RKKLSDQNGEKPVIQQAEKEIQENEANGDKQAAGQTNCVPEK------DEDGISEVNGEEGEQMR-IKVENESVKE-------------------ERDLEEIGQHNYSKSLVK-----KGSGFEEKEEE---------VMVKMEDSALFDSNVNFSESTVKRNETEETDVLAQ------QKKEEVEEQCLVHDKKARRQRIK------------RKRRLSMARRS-SKKNKTDSEKSHNDGKP-----------------------NNQQTQGKEPDSLHLTQ--PSNGTSASQAQCQSE---TFKPTAVRKQAFHNP--NRFSREPLYRVIRNQPPPVLSINLDHNLYKCNTPGCSKSFR--------------------KAKLLHYHMKYYHGEECPIEP------------EQTREMDKKTTLNSHDGSKKRCVTSRECAR------------VTVKNRS---LAPPTASTQNYQQW--------PLLKDKTRENQLDDTMQRCYNKERDRRFMEMESVKERNR------LKEKQRRDFLRIKLKEKKK-IRKTTSD-----------------------------------------------------------EDSISDWSSESCGWSEDEMEADLDVITSPLSCSSVASTTESQETVRCVCEADEENDFMLQCEECLYWQHGTCMGLLEENVPERYSCFICRDSSGLERRVRGQRQSLRYWYDRDWLSTGHMYGLSFLEN-YSHQNGKKIAATHQLLGDVQHVVEVLSGLQLKISVLQNQTHPDLKLWRQPWKPTE--RSRMKS-----KALHDAKTVSSSAGLETIENKE----AFSSSFQD-YISSEHCYQKPQTLYQVLEPRLVLKTRVESLLEDRLHSTERVPMNEQHYNGDMLKTSNSQ--LFN--HSKVIGEKCEAGADGGGDKSG------AQP----------------QQWKVNLLDHIETVQEEVTHRMDFIERELDVLENWLDCTGELEPPEPLDRLPELKHSIKQLLSELGKVQQVALTCAT-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B947-1", "uniprot_id": "A0A8M2B947_DANRE", "id": "A0A8M2B947-1", "name": "", "aln": "MTKSPPNRRGIVFEVGAQLEARDTLKNWYAANIEKIDYEDEKVLIHYRQWSHRYDEWFDWSSPYLRPVERIQLRKQGLNER-------------------------------QCASGFQVNQKVLASWSDCRYYPAKILSRDKDDFYTVKFFDGIIKTVKGIKVKPFRKQS------SDGRSNQQARK-RADQNEKELKPKE-NGNSRHNSSRHSVSDH------DGESESEADEDTTVMDESTDLQNGGEKE-------------------STETKMVNDSEVSSAEHQ-----PSEDQNQPSED---------KTENLEN-GNVEIKIEEEEEEEMDGGQEEAKVLHNGIDKNDEHKGEASDESPSLPKRTRSRTADGKEAEMVNGPELRKRRASTGQTSPAKRSRANSSTDRNTQTP-----------------------IKPVKSDSVPDTLDIKDEKTSPAGKPAPAEEAGS---TPELAAALKRQVHLPTTNKYSREPLYRVIKNQPPPILSIELDHNPFKCKMAGCLKSFR--------------------KASLLHYHMKYYHAQSDPSPPR----------CVQTRSSDKQSPSQETPRRRRTVSASHHTPS------------PLSDSKSGHSLSPPAVGIKHRQRS--------ATLGAERSKE--NQVFNRSLHDDRD-WVAKETALKERER------LREKRQREFFRIKLKKKKKKKRKSKSDSHSTEESIGPKPLPCNLNSAH---------------KLPLSLTHRSYTGHGPEKMLSQGEDSSSDLSSDSPVWSEDESDTELDLN-VPLSEQGVETVTHSSEIVRCICEVQEENDFMIQCDECLCWQHGTCMGLYEDSVPDSYSCYICRDPP-------AQRQSQRYWYDKDWLSSGHMYGLSFLEENYSHQNSKKVTAAHQLLGDVHRVFEVLNGLQLKMSILQTQAHPDLKLWRQPWKHADGLRRRMAGDSGIATPLPPSPPEMGENEFETLKSEAPSPMETHCSFQDSYISSEHCYQKPRTYYPAVERRLVVETRGGSELEDSLRSTEDLLEMAEQRYGTQLDHDQHK--LADRSFSKELESRMKRLVSAEQEKSCGVEIKEEEPDPVTPDPKPDPDLVLHQQWQLNLLEHIEAVQDEVTHRMDLIERELDVLESWLDYTGELEPPDPLARLPQLKHRIRQLLTDLGTVQQIALCSSSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BLG0-1", "uniprot_id": "PHF20_MOUSE", "id": "Q8BLG0-1", "name": "PHD finger protein 20", "aln": "MTKHPPNRRGISFEVGAQLEARDRLKNWYPAHIEDIDYEEGRVLIHFKRWNHRYDEWFCWDSPYLRPLEKIQLRKEGLHDE-------------------------------DGSSEFQINQQVLACWSDCRFYPARVTAVNKDGTYTVKFYDGVVQTVKHIHVKAFSKDQNIVGNARPKETDHKSLSSSPEKREKFKEQRKVTVNVKKDKVEKALKTEKRPKQPDKEGKLICSEKGKVSEKSLPKNEKEDKENIS----------------ENEREYSGDAQVEKKPEKDLVKNPQENLKEPKRKRGRPPSITPTAVDSNSQTLQPITLELRRRKISKRSDTPLKRPRLDKNSPQEQSKKRSENSDKDLSRRRSSRLSTNGTREILDPDSIVPDLVHTVDTNPLPDKSPSAKDSAEGQL-----------------------KSPLEAGQVSSALTCHPIGDGLGAADLELNCKSMGENTMKTEPVSPLAEVQEVSTVEVPNTLKKVDDSVTLNVPAVDLDH-KFRCKVLDCLKFFR--------------------KAKLLHYHMKYFHGMEKSPEPEEGP----GKTHVQTRGSAVPDKTSQESLTRKRVSASSPTAK------------EKEKTKE--KKFKELVRVKPKKKK--------KKKKKTKPECPCSEDISDTSQEPSPPKTFAVTRCGSSHK------PGVHMSPQLHGSDNGNHKGKLKTCE-------------------------------------------------------------EDNLSESSSESFLWSDEEYGQDVDVTTNPDE-ELEGDDRYDFEVVRCICEVQEENDFMIQCEECQCWQHGVCMGLLEENVPEKYTCYVCQDPP-------GQRPGFKYWYDKEWLSRGHMHGLAFLDQNYSHQNARKIVATHQLLGDVQRVIQVLHGLQLKMSILQSREHPDLQLWCQPWKQHSGEGRAHPR----HIHITDARSEESPS-YRTLNGAVEKPSPLPRSVEESYITSEHCYQKPRAYYPAVEQRLVVETRGSALDAAVSPLCENGDDSLSPRLGWPIDQDRSRGDIDPKPSSPKVREYISKNVLPEETPARKLLDRGGEG-----------LVSSQHQWQFNLLTHVESLQDEVTHRMDSIEKELDVLESWLDYTGELEPPEPLARLPQLKHCIKQLLTDLGKVQQIALCCST-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08923-1", "uniprot_id": "CTI6_YEAST", "id": "Q08923-1", "name": "Histone deacetylase complex subunit CTI6", "aln": "------------MESTAIVPKGPVVGSEDMEKAEVIASGSTDIISTTSTATT---------TAAIGSVQEESVKQEDVPME-------------------------------------GGEGEVEEEEGETRCICGELDTPDDSG-----FFIQCEQCSSWQHGYCVSITQD-----------------------------------------------------NAPDKYWCEQCRPELHQLFTTDTGEARSIYKP---------------VQEKRRQSRRKARSAAASK---------------------------------------SHAANEAEKSPRNTSNTDDNVDDIGDEEDEVEDEASAVALAKDGN------------------TRSSRRRRRNSMDDASTDQYSLD------------------------------------------------PGDSDK------------KLLDRKRATFMAREEKQYQR-----------------------------------------------------------MLEKALKESRRTSHQEDPE------------SYENDADIYQGDTDNHNGTTRLQTDVMLT------------------------------------------------EGKPDSVTNDDMKESLRPSKEQSMEKTNDVEKEAS-----------------------------------------------------------------------------------------------QEKESSTGSAQDTEKTDEPILPLTSISSSEDDSRKASSRGSKRVSKPARKGN-------------RTRRSNTSSDTNQNRRSADIGTDKP------------------------------------VKPRLPPQRTSLNEMRRRVSAILEFISRTQWELSEDQSDREEFVRFVEN------------------------------------------------------------------------------------------------------------------------------------------------------------------------QHFVEKVDTIYNGYNESLSMMDDLTRELLLWEKKYSNNTNAIQ----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* * : : . . * * . :: . : : .::. :::: .* : * ..: : :.. *: : . : . . : . . . . .. : . : . :: . . . . .. :: . . :: . . * : * : . .:. : . : * . . : .: :.: * : :.: * ::. :. . ::: * .: : : :: ** : :*: : *. . . : ", "identical_positions": 17, "similar_positions": 105, "identity": "1.39%" }, { "cls_id": "homologset.agr.SGD:S000006104", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XFW6-1", "uniprot_id": "WDR6_RAT", "id": "Q5XFW6-1", "name": "tRNA (34-2'-O)-methyltransferase regulator WDR6", "aln": "---------MDAFGDYVWPRATSELILLPVTGLECVG-DRLLAGEGPDLLVYNLDFGGHLRMVKRVQNLLGHYLIHGFRVQPEPKG------------DLDSEAMIAVFGSKGLRVVKISWGQSHLRELWRSGLWNMSDWIWDARWLEGN--------VALALGHNSVVLYDPVIGC-----MLQDVPCTDRCTLSSACLIGDTWKELTIVAGAVSNELLVWYPATALP-----DNKPVAPDRRVSGHVGVIFSMSYLESKGLLATASEDRSVRIWKVGDLRVPGGRVQN----IGHCFGHSARVWQVKLLEN----YLISAGEDCVCLVWSHEG--------EILQAFRGHQGRGIRAIAAHER-----QTWVITGGDDSGIRLWHLVG-----RGYPGLGVSSLSFKSPSRPGALKAVT--LAGSWRVLAVTDVGGLYLYDLEVKCWEQLLED-NRFQSYCLLEAAPGPEGFG-----LCALANGEGLVKVVPINTPTAAVDQNLFQGKVHSLSWALRGY---EELLLLASGPGGVVACLEISAAPTGKAIFVKERCR--YLLPPSKQRWHTCSAFLPPGD-FLVCGDRRGSVLLFPARPCLFKKPGVGPKAITAAEAPQAGSSSGGSESVVTGLGPVSSLHSLHGKQGVTSVTCHGGYVYSTGRDGSYYQLFVHGGRLQPVLRQKACRGMNWIAGLRMAP-------------------------DGSMVVLGFHANEFVVWSPRSHEKLHIVNCGGGHRSWAFS-----------DTEAAMAFAYLKDGDVMLYRALG--GCIRPNVILREGLHGREITCVKRVGTVTLGPEFEVPNLEHPDSLEPGSEGPGLIDIVITGSEDTTVCVLALPTTTGAAHALTAVCNHISSVRALAVWGVGTPGGPQDSH----PGLTAQVVSAGGRAEMHCFSLMITPDASTPSRLACHIMHLSSHRLDEYWDRQRNRHRMIKVDP-ETRYMSLAICELDSDRPGLGPGPLVAAACSDGAVRLFLLQDSGRILHLLAETFHHKRCVLKVHSFTHEAPNQRRRLILCSAATDGSIAFWDLTT----AMDRGSTTLEPPAHPGLPYQMGTPCLTVQAHSCGVNSLHTLP------TPEGHHLVASGSEDGSLHVFTLAVKMPELEEADGEAELVPQLCVLDEYSVPCAHAAHVTGIKILSPKLMVSASIDQRLTFWRLGNGEPTFMNSTVYHVPDVADMDCWPVN--PEFGHRCALAGQGLEVYNWYD----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99ME2-1", "uniprot_id": "WDR6_MOUSE", "id": "Q99ME2-1", "name": "tRNA (34-2'-O)-methyltransferase regulator WDR6", "aln": "---------MDAFGDYVWPRATSELILLPVTGLECVG-DRLLAGEGPDLLVYNLDLGGHLRMVKRVQNLLGHFLIHGFRVRPEPKG------------DLDSEAMIAVFGSKGLKVVKVSWGQSHLRELWRSGLWNMSDWIWDVRWIEGN--------VAVALGHNSVVLYDPVIGC-----MLQDVPCTDRCTLSSACLVGDTWKELTIVAGAVSNELLIWYPATALT-----DNKPVAPDRRVSGHVGVIFSMSYLESKGLLATASEDRSVRLWKVGDLRVPGGRVQN----IGHCFGHSARVWQVKLLEN----YLISAGEDCVCLVWSHEG--------EILQAFRGHRGRGIRAIATHER-----QAWVVTGGDDSGIRLWHLAG-----RGYPGLGVSSLSFKSPSRPGALKAVT--LAGSWRVLAVTDVGSLYLYDLEVKSWEQLLED-NRFRSYCLLEAAPGPEGFG-----LCALANGEGLVKVVPINTPTAAVEQKLFQGKVHSLSWALRGY---EELLLLASGPGGVIACLEISAAPTGKAIFVKERCR--YLLPPSKQRWHTCSAFLPPGD-FLVCGDRRGSVMLFPVRPCLFKKPGAGSKAITAAEAPGAGSGSGGSESVPTGIGPVSTLHSLHGKQGVTSVTCHGGYLYSTGRDSSYFQLFVHGGHLQPVLRQKACRGMNWVAGLRMVP-------------------------DGSMVILGFHANEFVVWSPRSHEKLHIVNCGGGHRSWAFS-----------DTEAAMAFTYLKDGEVMLYRALG--GCIRPNVILREGLHGREITCVKRVGTVTLGPEFEVPNLEHPDSLEPGSEGPGLIDIVITGSEDTTVCVLALPTTTGSAHALTSVCNHISSVRALAVWAVGTPGGPQDTR----PGLTAQVVSAGGRAEIHCFSVMVTPDASTPSRLACHVMHLSSHRLDEYWDRQRNKHKMIKVDP-ETRYMSLAICELDNDRPGLGPGPLVAAACSDGAVRLFLLQDSGRILHLLAESFHHKRCVLKVHSFTHEAPNQRRRLILCSAATDGSLAFWDLTT----AMDKGSTTLELPAHPGLPYQMGTPSMTVQAHSCGVNSLHTLP------TPEGHHLVASGSEDGSLHVFTLAVKMPEPEEADGEAELVPQLCVLEEYSVPCAHAAHVTGVKILSPKLMVSASIDQRLTFWRLGQGEPTFMNSTVYHVPDVADMDCWPVS--PEFGHRCALAGQGLEVYNWYD----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NNW5-1", "uniprot_id": "WDR6_HUMAN", "id": "Q9NNW5-1", "name": "tRNA (34-2'-O)-methyltransferase regulator WDR6", "aln": "---------MDALEDYVWPRATSELILLPVTGLECVG-DRLLAGEGPDVLVYSLDFGGHLRMIKRVQNLLGHYLIHGFRVRPEPNG------------DLDLEAMVAVFGSKGLRVVKISWGQGHFWELWRSGLWNMSDWIWDARWLEGN--------IALALGHNSVVLYDPVVGC-----ILQEVPCTDRCTLSSACLIGDAWKELTIVAGAVSNQLLVWYPATALA-----DNKPVAPDRRISGHVGIIFSMSYLESKGLLATASEDRSVRIWKVGDLRVPGGRVQN----IGHCFGHSARVWQVKLLEN----YLISAGEDCVCLVWSHEG--------EILQAFRGHQGRGIRAIAAHER-----QAWVITGGDDSGIRLWHLVG-----RGYRGLGVSALCFKSRSRPGTLKAVT--LAGSWRLLAVTDTGALYLYDVEVKCWEQLLED-KHFQSYCLLEAAPGPEGFG-----LCAMANGEGRVKVVPINTPTAAVDQTLFPGKVHSLSWALRGY---EELLLLASGPGGVVACLEISAAPSGKAIFVKERCR--YLLPPSKQRWHTCSAFLPPGD-FLVCGDRRGSVLLFPSRPGLLKDPGVGGKARAGAGAPVVGSGSSGGGNAFTGLGPVSTLPSLHGKQGVTSVTCHGGYVYTTGRDGAYYQLFVRDGQLQPVLRQKSCRGMNWLAGLRIVP-------------------------DGSMVILGFHANEFVVWNPRSHEKLHIVNCGGGHRSWAFS-----------DTEAAMAFAYLKDGDVMLYRALG--GCTRPHVILREGLHGREITCVKRVGTITLGPEYGVPSFMQPDDLEPGSEGPDLTDIVITCSEDTTVCVLALPTTTGSAHALTAVCNHISSVRAVAVWGIGTPGGPQDPQ----PGLTAHVVSAGGRAEMHCFSIMVTPDPSTPSRLACHVMHLSSHRLDEYWDRQRNRHRMVKVDP-ETRYMSLAVCELD--QPGLG--PLVAAACSDGAVRLFLLQDSGRILQLLAETFHHKRCVLKVHSFTHEAPNQRRRLLLCSAATDGSLAFWDLTT----MLDHDSTVLEPPVDPGLPYRLGTPSLTLQAHSCGINSLHTLP------TREGHHLVASGSEDGSLHVFVLAVEMLQLEEAVGEAGLVPQLRVLEEYSVPCAHAAHVTGLKILSPSIMVSASIDQRLTFWRLGHGEPTFMNSTVFHVPDVADMDCWPVS--PEFGHRCALGGQGLEVYNWYD----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BEZ5-1", "uniprot_id": "A0A8M2BEZ5_DANRE", "id": "A0A8M2BEZ5-1", "name": "tRNA (34-2'-O)-methyltransferase regulator WDR6", "aln": "MKSTACCADCEMASPVESAVVKSAVLVAPITALEFLGEDFLLTGEGPILSVYSLQAS---PKKCASINVLQNYRIHGIRPYKKHQSGGIPFSGASSASDNSYKGDIIVFGGKGVRLVSFESEGQCLKLIG--PLLELQDWVLDIHCFKRQP----HSLLGISLAHNAIMLLEAESGN-----IISFYSCVETCLLYSALMVGPNWDSVVLVGGTVFNQLVLWRPAGTKL-----SGQ-SQVERRLLGHSGVIFSLCYLQESGWLASASDDRSVRLWSVGTLGGDAGCGKESPTCLRVLYGHQARVFCVKLTPS----RLFSAGEDGACLLWEWGGEG------KVGCAFRGHKSGGVRALAVSEGSISCRAGWVATGGADGGVRLWRVAEGKKISEETQEETQLDLGFRGHGCPKVVRLVG--EGESNAILVCTDQGEVCLS--QGDIWDVIWQGGSEFQSYCVMEVASIQVQNSDCIVQVCAVGNLNGGVQVFLVGQPGVGVFLRAGEGKVHSVLWVKGLFGESGNVCLLASGSEGLVYRWTINVTEDKSGLHIKEEALLPFLLPPCAKRWLTAAVTLSQRNGFCLCGDRRGSLLLYMER----ENNDRINEGEESRIDSQDQETENRQTELVSSLSPISTLYGVHGKQGVTSVCEYQDLCYSTGRDGSVRILTVEESTLKVRRVHRACKGMDWLEMVLFLGSDGPERMLNKTIVKRTNDTGRESIAEARFVMVGFHSVHFVIWDPHRQEKLLSVTCGGGHRSWAFKRPISTHIDTQTQALRQGTLVFIKQGAVMASRSLMSTDTSVNGHTLKEGLHGRGISCVCHLGSLSG-------------------DLSELWEVFVTGGEDTTVGVLAVCPQSGIVKVLAVLTDHISIVRALAAIRRGDMNERERNNGMETSVLSSLVFSAGGRAQLQCYRLLIHLD-EQQSQPICQVTQIAGHRLDEQWERKRNRHKTVKMDP-ETRYMSIAVVQNE------SEGVLLALGCSDGAVRLFSVNESSRSVDVLWECFYHQRCVLSVATCKLEDSQGRKLLLLFSATTDGCISVWDLTA----VLNSKASVSWQGPS--------VPFFSIPVHQSGVNTLALSPRTEKGQTEDNVISLASGGDDGQLSLLRIKIDQAEQE------NGVASLQLLSHWSIPLAHSSPLTGLCLLSPALLASTSPDQRMCLWSVESDGLRPLQVRFSHIADAAGLWAWRSEG-QEGGAWIVVCGQGLQLFQLTEKEIDEAENGRAEGEERKKVMFSHQCSRT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08924-1", "uniprot_id": "WDR6_YEAST", "id": "Q08924-1", "name": "tRNA (34-2'-O)-methyltransferase regulator RTT10", "aln": "--------------------MKDLSHYGPALCVKFYN-DYVLAGYGPFIHVYDYHSATLINKCR----LFHYNKVHGLSLSS--------------------EGKILAYGARSVTIVELEDVLKKESLVDFERIN--SDWITGATFSFDN------LQIYLLTCYNKVLICDLNCEV-----LFRKSLGGERSILYSGIIKVFGPDKVYVNAGTVMGGVIIWDLFSETK-----IHN-------LLGHEGSIFYVNLSNNGRYVASCSDDRSIRLWDLETGKQ-----------LSVGWSHTARIWNLMFFDNDS--KLISVSEDCTCRVWNIIESRENVAELSISNVYEVHLIKSIWGVDVKDD-----EMIAVTSGNDGRLKLIDLLQLKRHGDEETSFSLDDIAKQCGDIFEKNESIKGFQWFSFGVIAITSLGKILKYSDVTKQWKLLLTN-EKFNSYPITNGIQTQNIAV------FSNNKSDILLIKFSKDSADIIETEEFHLDELSKTNNCLVTEYDDDSFLLTLQSPNPREKFVCLEISLQNLKIKSKHCFN--------KPENFSSSCLTSFRN-HILVGSRFSTLVIYNLLD----------ESEEPFIIRRLSPGDTTTSIEFVEDKDNSAVFSVTNRDGYYVFIELTKNSLEEGPYRLSYKVLHSNKMMK-----------GFLEGAFFNS-------------------------KGEYITYGFKSSLFYLYNETNCYELASEVCGGSHRLWNLA-----------KITDGHVLMYIKASRFHLRKIYN----SIVPETLENGVHGREIRDISICPVSNTNTN----------------DNFKDGHIFCTASEDTTIKLGYFNNRTGKVQNFWTQRKHVSGLQRCQFIN------------------HKLMISSSAREELFLW------------------------ELNDKYNKRPYMTIRQALPV-STNNSDLRIMDFDVKFISQSGDFLLVTVYSDSTIKIWHYRENQNKFDLIMQGRYKTCCLFNVVFIALK-----EELLVVISPTDGHLVVYNITEYVPFSVDPISGDLVDHKLDATISNLPAPVAQLPVHQSGVKSLDYVAN-----ATRTSATILTGGDDNGLGLSNLKLDD-----------SNKVTLKTSDFIAAAASSTITSGMLINGGKEVITTSVDQVIRAWEITAGKLSLVDKKRTTVADTGSLEIISNDEDADSEKTLLIGGVGLSIWKK------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q86B53-1", "uniprot_id": "WDR6_DROME", "id": "Q86B53-1", "name": "tRNA (34-2'-O)-methyltransferase regulator WDR6", "aln": "-----------------------MVLISDAFGLEISP-NGILVGHGDQAVLYSSEPKVELPVQLR------EGKVRGFAWSSLRKS----------------QRLLLLYSENEYSLIRCTTSSEN-DLFQLVYEGETRDWINAALFLEDENESEDRKRFVLHTSHSALLYMEYDLTSNADCTVLELARCTDSSILYYTKLHGSSFNKLAIISGNAFGELLVWQTQFPTESDPKSVMKTYPLLLRIEAHNGVIHSIEFDLQSQLLVTTSDDRSVKFWNIQKSGDWTTAEIKP---MFSCYGHSSRVMCVVILKIDDRTFVASGGEDSYVCIWSSSG--------ELILKRRQQFGAPIWRLGFSQD-----AEILYSTSSTGNLVGQNLKEVLN--RPKIESTILSSLGDANEFVRNLKFVN--NEIIVGLSSLNRLYYTRISPDSSHENKWLMVN--DFPSYKRTVLEVFDDIIAT-----CGHRRITLHRYNTNTNDFEQLFDGIRMKGTIRSFQFLSRDR---------YLVSDNLGYCLLLQTHQLHIESHIALFNN--------REPWITAALLISEQY--LLLGNREGHVMLYCRSS----------ASDDFQLKDSIRYLHGKMGSNFFKLLSLNADNAHVMSGGHEAFLKYLSVRFSDSTLRVSQREGIP---------------LAWVEASPSDD-----------------------------LILGFNDNHIVAWS-RRNDILLQLACGGGHRCWDFRLS---------DGDSQLSIAYVKQKRVYFYRNSLY--NAVDNRLKDIEPNNWHVRNCNTLRLITP--------------------RNQSDPFILSAGDDNIIKVTQVTNDS--LSQRAEMHSHISTVRSLQAIPYKSNGGDSS---------TWLVFSVGGRSQLCISQLSIDAS-------------------NKCWISEISSHTLHNVAASKTSTIEARLMAIDVVQHSDGDLFSIYVAGGDGNISHYIWELETPNQLDLKHFVDIQRCPLGIQWIASKG-------MLLVSTTNGEVYGFDRTL-------------------------ETTYFQLQLHVTGINTIDIYVD-------RHLLHILSGGDDESIKYTVLNLNNN---------NVEQKIEYLGLHNAQVNALAIHCPTKSVAASELFAYTCSIDRQIYRIDLSTHKYKRVGYTCIADVKGMLLDEHQR-------MYFYGCGLQTMSISNIL--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : :*.* * :*. . ::*: : : :. . :: . **: : . : :. :: : :: : . * : ..: : .* . . :::* : : .* * *. : . :.: *:***:::*.: : :.* :*: : : : * .** :*. .: . : : : : : . . : : . : : . . . : . * ** . . . . : . . :. :.: . : *.* . :::: . .: . * . . :: : **: : :. * ***.** * : . : ::* . : :. : . .. : .:*. : : . : .*:* :: :.* ..* :: :. : . : .* . : : . : .*. : : . . : . * : : : :: :.*:* : :: * .. : * *:::: : :*.:* : : :. : . : : : . : : . :.*. .: . . * **. . ", "identical_positions": 59, "similar_positions": 217, "identity": "4.58%" }, { "cls_id": "homologset.agr.SGD:S000006109", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O95544-1", "uniprot_id": "NADK_HUMAN", "id": "O95544-1", "name": "NAD kinase", "aln": "MEMEQEKMTMNKELSPDAAAYCCSACHGDETWSYNHPIRGRAKSRSLSASPALGSTKEFRRTRSLHGPCPVTTFGPKACVLQNPQTIMHIQDPASQRLTWNKSPKSVLVIKKMRDASLLQPFKELCTHLMEEN--MIVYVEKKVLEDPAIASDESFG-AVKKKFCTFREDYDDISNQIDFIICLGGDGTLLYASSLFQG-SVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVKELRGKKTAVHNGLGENGSQAAGLDMDVGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARN-----TAWVSFDGRKRQEIRHGDSISIT------------------------TSCYPLPS--ICVRDPVSDWFESLAQCLHWNVRKKQAHFEEEEEEEEEG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q06892-1", "uniprot_id": "POS5_YEAST", "id": "Q06892-1", "name": "NADH kinase POS5, mitochondrial", "aln": "-------MFVRVKLNKPVKWYRFYSTLD------SHSLKLQSGSKFVKIKPVN----------NLRSSSSADFVSPPNSKLQS--------------LIWQNPLQNVYITKKPWTPSTREAMVEFITHLHESYPEVNVIVQPDVAEEISQDFKSPLENDPNRPHILYTGPEQDIVNRTDLLVTLGGDGTILHGVSMFGNTQVPPVLAFALGTLGFLSPFDFKEHKKVFQEVISSRAKCLHRTRLECHLKKKDSNSSIVTH-------------------------AMNDIFLHRGNSPHLTNLDIFIDGEFLTRTTADGVALATPTGSTAYSLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPHSSHIRIKIGSKLNQKPVNSVVKLSVDGIPQQDLDVGDEIYVINEVGTIYIDGTQLPTTRKTENDFNNSKKPKRSGIYCVAKTENDWIRGINELLGFNSSFRLTKRQTDND-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. :*. . * : . .*.:: :: *: :. .*. .*:..... ..* . **. * *::. :.* : ** .* :.: *: *** *. : * *: .* *: : ...: :: . : :** *: *::: ******:*:. *:* . .****:** **:****:**.*::.:. . :**...* : *:**: :: *: ... ..* .:*::.:.** *.:*:*:*:::**.::* . .*** ::********: :**.*:: * ****::*****:******:::* . .::* :..: .: .. :*.** :*:: **.* : .* * * ** .. .**:..: : * :* : :: : ::: ", "identical_positions": 119, "similar_positions": 158, "identity": "24.74%" }, { "cls_id": "homologset.agr.SGD:S000006110", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BMT9-1", "uniprot_id": "HHAT_MOUSE", "id": "Q8BMT9-1", "name": "Protein-cysteine N-palmitoyltransferase HHAT", "aln": "-----------------------------------------------------------------------------MLPGWELTLCLLVSLGFHFRSFYEVYKVSREHEEELDQEFELEMD-TLFGGLKKDPTDFEWNFWMEWGKRRLVWLFIGHMAVSQLATLLTKKHRPWIVMVYGMWACWCV----LGAPGVVMVLLHSTIAFCVAQFRSVLLSWLCSLLLLST-------------LRLQSVEEVKRRWYKTENEYYLLQFT--LTVRCLYYTSFSLELCRQPPSAQP--------------------------------TPSAQGASHSYPWLLTYVFYYPVFHNGPILNFPEFFRQMQQPELNSLQHSLCIVAKGLGRLLCWWWLAELMVHLMYMHALYSSAPLLESVSCWTLGG-LALAQVLFFYVKYLVLFGVPALLMRLDGLTPPP-LPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPLGGSQHGLLGTLLSTATTFAFVSYWHGSYEDLWCWAALNWLGVTVESGVRRLLETPCVRETLARHLSPQAHHRLHALLAACSTSMLILFNLV-FLGGIQVGKTYWNRIFLQGWPWVTLSVLGFLYCYSHVDIAWAQTYTVL-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GIY5-1", "uniprot_id": "A0A8I6GIY5_RAT", "id": "A0A8I6GIY5-1", "name": "", "aln": "MYRAPANPLSRQPGATSQAKAFTPAASDRRSPQPSRVLPGPGLRAAGCRDAFFPAHSALHAAIQKLSTLHWEAESPAMLSRWELTLCLLVSLGFHFRSFYEVYKVSREHEEELDQEFELEMD-TLFGGLKKDPTDFEWNFWLEWGKQRLVWLLLGHMAVSQLATLLTKKHRPWIIMIYGMWACWCV----LGAPGVVMVLLHTTIAFCVAQFRSMLLSWLCSLLLLST-------------LRLQSVEEVKRRWYKTESEYYLLQFT--LTVRCLYYTSFSLELCRQPP--------------------------------------SAQRACFSFPWLLTYVFYYPVFHNGPILNFPEFFRQMQQPELSSLQHSLCILAKGLGRLLCWWWLAELMVHLMYMHALYSSIPLLESVSCWTLGG-LALAQVLFFYVKYLVLFGAPALLMRLDGLTPPP-LPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPLGGSQHGLLGTLLSTAMTFAFVSYWHGSYEDLWCWAALNWLGVTVESGVRRLLQTPCVRETLARHLSPQARRRLHALLASCSTSMLILFNLV-FLEGIQVGKTYWNRIFLQGWPWVTLSVLGFLYCYSHVGIAWAQTYTVL-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5VTY9-1", "uniprot_id": "HHAT_HUMAN", "id": "Q5VTY9-1", "name": "Protein-cysteine N-palmitoyltransferase HHAT", "aln": "-----------------------------------------------------------------------------MLPRWELALYLLASLGFHFYSFYEVYKVSREHEEELDQEFELETD-TLFGGLKKDATDFEWSFWMEWGKQWLVWLLLGHMVVSQMATLLARKHRPWILMLYGMWACWCV----LGTPGVAMVLLHTTISFCVAQFRSQLLTWLCSLLLLST-------------LRLQGVEEVKRRWYKTENEYYLLQFT--LTVRCLYYTSFSLELCWQQL--------------------------------------PAASTSYSFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQQEHDSLKASLCVLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGG-LALAQVLFFYVKYLVLFGVPALLMRLDGLTPPA-LPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRRFHAALASCSTSMLILSNLV-FLGGNEVGKTYWNRIFIQGWPWVTLSVLGFLYCYSHVGIAWAQTYATD-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D1G3-1", "uniprot_id": "HHATL_MOUSE", "id": "Q9D1G3-1", "name": "Protein-cysteine N-palmitoyltransferase HHAT-like protein", "aln": "------------------------------------------------------------------------MGIKTALPAAELGLYSLVLSGALAYAGRGLLEASQDGAHRKAFRESVRPG-WEYLGRKMDVADFEWVMWFTNFRNVIVFALSGHVLFAKLCTMVAPQLRSWMYAVYGVLAVVGT----MGPWYLLLLLGHCMVLYVASLLGQRWLCLALGLASLAS-------------FKVDPGISWQSGFVTGTFDLQDVLFHGGSSFTVLRCTSFALESCAHPD------------------------------------------RRYSLADLLKYNFYLPFFFFGPIMTFDRFHAQVSQ-EPVRPEGELWHIQAQAGLSAAAIVAVDVFFHFFYILTIPSDLKFASRLPDSALAG-LAYSNLVYDWVKAAVLFGVVNTVARLDHLDPPQ-PPKCITALYVFG--ETHFDRGINDWLCKYVYDHIGGDHSTVIPELAASVATFVVTTLWLGPCDIVYLWSVLNCFGLNFELWVQKLAERGPLAQIEAR-LSEQMSRRVRALCGAVNFWAIIMYNLV-SLNSLEFTELVARRLILTGFPQTTLAVLFVTYCGVQLVKERERSLALEEEQRQDREKLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VZU2-1", "uniprot_id": "HHAT_DROME", "id": "Q9VZU2-1", "name": "Protein-cysteine N-palmitoyltransferase Rasp", "aln": "---------------------------------------------------------------------MSRLPDRSLLTRCEIFVYFGVYIAYIVVGLYKIYGLRDHIVKEAKFQFPEGWSLYPFSQRRRDDSNDELENFGDFIVSFWPFYLL-HVAVQGFIRWKRPRLQCLGFIGVCALALSVN----LDWSSMVLLVTLIASYYIVSLLSLKFLVWLLSAGWILC-------------INVMQKNVWWTDRVG-YTEYVLVIVT--MSWSVLRGCSYSLSKIGAKQ---------------------------------------EDLTRYSLVQYLGYAMYFPCLTYGPIISYQRFAARREDEVQNWLG-----FVGGVLRSAIWWLVMQCALHYFYIHYMSRDVRMVEMMDSVFWQHSAGYFMGQFFFLYYVVTYGLGIAFAVQDGIPAPN-RPRCIGRIHFYSDMWKYFDEGLYEFLFQNIYAELCGKRSSAAAKFGATALTFAFVFVWHGCYTYVLIWSILNFLCLAAEKVFKTFTAMPEYQRWTQRHLGAVGAQRLYAMLATQLFIPAAFSNVY-FIGGQEIGDFLMRGAYLSGVG-NYVALCFCSYCFFQCSELLLTKSDGRSKTKTF-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08929-1", "uniprot_id": "GUP2_YEAST", "id": "Q08929-1", "name": "Membrane-bound O-acyltransferase GUP2", "aln": "----------MSMLRIWSCIVHFFSVQALDSRIKPDIEFKRRQRIFINSSKEENGSSSSAVTVTRNPVLSSNSPSPPLWNTWEFRLYYLAFTVVVPFMIKAALATSSE-SNPNYYKFSGLLAHGWILGRKVDNSDPQYRFFRSNFFLLAILILLQIILKKVFVKFSKIPKTKFDFACGLVFVCFMYGINSVKLFTHAFIFFTLAHSLKRKRLIAAFAIWSYGIFTLFINQKMKNLPFNNIAIILSPMDQWYKGIVPRWDFFFNFTLLRLLSYSMDFLERWHEQLSRQPSIDYDDRRPEFRKSLSGSTLQTIYESGKNVLEEKERLVAEHHIQDYNFINFIAYITYAPLFLVGPIITFNDYLYQSENKLPSLTKKN---IGFYALKVFSSLLLMEIILHYIYVGAIARTKAWNN--DTPLQQAMIALFNLNIMYLKLLIPWRLFRLWAMVDGIDAPENMLRCVDNNYSTVGFWRAWHTSFNKWVIRYIYVPFGGSNN----KILTSFAVFSFVAIWHDIQLRVLFWGWLTVLLLLGETYITNCFS---------RYRFRSWYRFVCGIGAAINICMMMIINVYGFCLGAEGTKLLLKGIFNNSHSPEFLTAVMVSLFIAVQVMFEIREEEKRHGINLKC----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : . . . . : * :: : : : : : . : ::. : . : : : . . : : . .. : * * * : ***:.: : : .: . : * :*: : . . :: : : * : .* :*: . :. .: .:: : :* . *.. : :: .* .. * . : *. *. : : * . * : . . .: : *: . : . . . :: ", "identical_positions": 22, "similar_positions": 95, "identity": "3.43%" }, { "cls_id": "homologset.agr.SGD:S000006111", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V9R8-1", "uniprot_id": "HNRPC_RAT", "id": "G3V9R8-1", "name": "Heterogeneous nuclear ribonucleoprotein C", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASNVTNKTDPRSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIVGCSVHKGFAFVQYVNERNARAAVAGEDGRMIAGQVLDINLAAEPKVN-----RGKAGVKRSAAEMYG-------------SSFDLDYDFQR-DYYDRMYSYPARVPP-PPP-IARAVVPSKRQRV--SGNTSRRGKSGFNSKSGQRGSSSKS------------------------VKGDDLQAIKKELTQIKQKVDSLLESLEKIEKEQSKQADLSFSSPVEMKNEKSEEEQSSASVKKDETNVKMESEAGADDSA----------EEGDLLDDDDNEDRGDD------------------------------------QLELK-DDEKEP----EEG---------------------------------------------------------------------------------------------------EDDRDSANG--EDDS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z204-1", "uniprot_id": "HNRPC_MOUSE", "id": "Q9Z204-1", "name": "Heterogeneous nuclear ribonucleoproteins C1/C2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASNVTNKTDPRSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIVGCSVHKGFAFVQYVNERNARAAVAGEDGRMIAGQVLDINLAAEPKVN-----RGKAGVKRSAAEMYGSVPEHPSPSPLLSSSFDLDYDFQR-DYYDRMYSYPARVPP-PPP-IARAVVPSKRQRV--SGNTSRRGKSGFNSKSGQRGSSSKSG----------------------KLKGDDLQAIKKELTQIKQKVDSLLESLEKIEKEQSKQADLSFSSPVEMKNEKSEEEQSSASVKKDETNVKMESEAGADDSA----------EEGDLLDDDDNEDRGDD------------------------------------QLELK-DDEKEP----EEG---------------------------------------------------------------------------------------------------EDDRDSANG--EDDS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07910-1", "uniprot_id": "HNRPC_HUMAN", "id": "P07910-1", "name": "Heterogeneous nuclear ribonucleoproteins C1/C2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASNVTNKTDPRSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIVGCSVHKGFAFVQYVNERNARAAVAGEDGRMIAGQVLDINLAAEPKVN-----RGKAGVKRSAAEMYGSVTEHPSPSPLLSSSFDLDYDFQR-DYYDRMYSYPARVPP-PPP-IARAVVPSKRQRV--SGNTSRRGKSGFNSKSGQRGS-SKSG----------------------KLKGDDLQAIKKELTQIKQKVDSLLENLEKIEKEQSKQA-------VEMKNDKSEEEQSSSSVKKDETNVKMESEGGADDSA----------EEGDLLDDDDNEDRGDD------------------------------------QLELIKDDEKEA----EEG---------------------------------------------------------------------------------------------------EDDRDSANG--EDDS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O60812-1", "uniprot_id": "HNRC1_HUMAN", "id": "O60812-1", "name": "Heterogeneous nuclear ribonucleoprotein C-like 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVN-----RGNAGVKRSAAEMYG-------------SSFDLDYGFQR-DYYDGMYSFPARVPP-PPP-IALAVVPSKRQRL--SGNTSRRGKSGFNSKSGKRGS-SKSG----------------------KLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEQSKQE-------VEVKNAKSEEEQSSSSMKKDETHVKMESEGGAEDSA----------EEGDPLDDDVNEDQGDD------------------------------------QLELIKDDEKEA----EEG---------------------------------------------------------------------------------------------------EDDRDSTNG--QDDS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B2RXH8-1", "uniprot_id": "HNRC2_HUMAN", "id": "B2RXH8-1", "name": "Heterogeneous nuclear ribonucleoprotein C-like 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASNVTNKMDPHSVNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVAVINLAAEPKVN-----RGNAGVKRSAAEMYG-------------SSFDLDYGFQR-DYYDGMYSFPARVPP-PPP-IALAVVPSKRQRI--SGNTSRRGKSGFNSKSGKRGS-SKSG----------------------KLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEQSKQE-------VEVKNAKSEEEQSSSSMKKDETHVKMESEGGAEDSA----------EEGDPLDDDDNEDQGDN------------------------------------QLHLIKNNEKDA----EEG---------------------------------------------------------------------------------------------------EDNRDSTNG--QDDS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DMR1-1", "uniprot_id": "HNRC4_HUMAN", "id": "P0DMR1-1", "name": "Heterogeneous nuclear ribonucleoprotein C-like 4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVN-----RGNAGVKRSAAEMYG-------------SSFDLDYNLQR-DYYGGMYSFPARVPP-PPP-IALAVVPSKRQRI--SGNTSRRGKSGFNSKSGKRGS-SKSG----------------------KLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQG-------VEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSV----------EEGDLLCDDDNEDQGDN------------------------------------QLELIKDDEKGA----EEG---------------------------------------------------------------------------------------------------EDDRDRANG--QDDS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TXW0-1", "uniprot_id": "A0AB32TXW0_DANRE", "id": "A0AB32TXW0-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVAFGFSWISAKHGRTVTCCMLKKVIICEGWVIGRRWKALVGTQGGLIATTVTSNPQYCSWKCCSLVWCWNCDFAARNLQCDLLSSINPNAMDRASSASQLIASNVTNKTDPRSLNSRVFIGNLNTMLVTKADVEAIFSKYGKIVGCSVHKGYAFVQFAQERNARTAVQGEDGRMVVGQVLDVNLAGEPKPH-----RSKT-TKRSAGDMYSSS-----------SSFELDYDFQR-DYYDRMYSYPSRVPA-PPP-LSRAVIPSKRPRVSTSGATSRRTKSSFAT-SSKSSQRTSSR----------------------TLKADDLQTIKRELSQIKHKVDFLLESLDRMEKDHGKKS--------EGKSVKAEVGEVSPLQHSSKKEREREEQE-INDSE----------EERDLLGEEEEEEEEEEVCVVVAGGRHPKPCDILMLLRLTSVFVLLRLKARVERMRMRKRKEKRKRVSMKKGKMMAIALMVTTRNFKRSGYQTSTQISALS--------------------------------------------------------VLLKRLKQVFKRSIYDDVDVCALILADTAITSV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PNP7-1", "uniprot_id": "A0A8M9PNP7_DANRE", "id": "A0A8M9PNP7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDHSPTTSSLMASNVTNKTDPRSLNSRVFIGNLNTMLVTKADVEAIFSKYGKIVGCSVHKGFAFVQYANERNARAAVNGEDGRMIVGQVLDINLAGEPKPH-----RSKT-IKRSAGDMYSS-------------SFDLDYDFQR-DYYDRMYSYPSRVPP-PPPPLSRAVIPSKRARVSVSG--SRRTKSSFSSKSSQRTSRTSETRTLISHCNKKSGCFDLKIYRHIQMRADDLQTIKKELTQIKHKVDYLLESLERMERDHSKKS--------DVKSAKAE--EVSP-QHGKK---DRENSE-MNDYE----------DEGDLLEEEE-------------------------------------IKS-----RGREDDEEEEDGEQEEG---------------------------------------------------------------------------------------------------EDDGDSAN---GDHA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q64012-1", "uniprot_id": "RALY_MOUSE", "id": "Q64012-1", "name": "RNA-binding protein Raly", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLKIQTSNVTNKNDPKSINSRVFIGNLNTAVVKKSDVETIFSKYGRVAGCSVHKGYAFVQYANERHARAAVLGENGRVLAGQTLDINMAGEPKPN-----RPK-GLKRAATAIYS--------------GYSFDYDYYQDYFCARLFDYRGRLSPVPVP----RAVPVKRPRV--TVPLVRRVKTTIPVKLFARSTAVTTG------------------SAKIKLKSSELQTIKTELTQIKSNIDALLGRLEQIAEEQKANP--------DGKKKGDSSSGGGGGSS-GGGGSSNVGGGSSGGSGSCSSSSRLPAPQEDTASEAGTPQGEVQ--------------------------------------TRDDGDEEGLLTHSEEEL--------------------------------------------------------------------------------------------------EHSQDTDAEDGALQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PTI6-1", "uniprot_id": "E9PTI6_RAT", "id": "E9PTI6-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLKIQTSNVTNKNDPKSINSRVFIGNLNTAVVKKSDVETIFSKYGRVAGCSVHKGYAFVQYANERHARAAVLGENGRVLAGQTLDINMAGEPKPN-----RPK-GLKRAATAIY------------------------------RLFDYRGRLSPVPVP----RAVPVKRPRV--TVPLVRRVKTTIPVKLFARSTAISTG------------------SAKIKLKSSELQTIKTELTQIKSNIDALLGRLEQIAEEQKANP--------DGKKKGDSSSGGGGGSSSGGGGSGNVGSGGSGGSG--SSSSRPPAPQEDTASEAGTPQGEVQ--------------------------------------TRDDGDEEGLLTHSEEELPLFLVSLTGALAISRRASLSQASSQA----------------------------------------------------------------------PISGCQSRESTRGRLAAVTSLPIASQPVSATSFASGVTGLPLSHALFLSALPGPRGRSTLLFFSQDIPRLGVFL---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UKM9-1", "uniprot_id": "RALY_HUMAN", "id": "Q9UKM9-1", "name": "RNA-binding protein Raly", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLKLQASNVTNKNDPKSINSRVFIGNLNTALVKKSDVETIFSKYGRVAGCSVHKGYAFVQYSNERHARAAVLGENGRVLAGQTLDINMAGEPKPD-----RPK-GLKRAASAIYS--------------GYIFDYDYYRDDFYDRLFDYRGRLSPVPVP----RAVPVKRPRV--TVPLVRRVKTNVPVKLFARSTAVTTS------------------SAKIKLKSSELQAIKTELTQIKSNIDALLSRLEQIAAEQKANP--------DGKKKGD---GGGAGGGGGGGGSGGGGSGGGGGGG----SSRPPAPQENTTSEAGLPQGEAR--------------------------------------TRDDGDEEGLLTHSEEEL--------------------------------------------------------------------------------------------------EHSQDTDADDGALQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QAY0-1", "uniprot_id": "F1QAY0_DANRE", "id": "F1QAY0-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLKVQTSNITNKNDPKSINSRVFIGNLNTAVVKKSDVETIFSKYGRVLGCSVHKGYAFVQYANERHARGAVIGENGRVLAGQTLDINMAGEPKPN-----RPK-GLKRSAATLYS--------------GYDFDYDYYRDDFYDRLFEYRGRVS--PVP----RAVPVKRPRV--AVPVVRRVKS-LPVKLLTRSAILPNS------------------SVKHKLKSTELQAIKSELTQIKSNIDALLGRLDQITEDKYCST--------ELQKAEDLKSEASQDES----GS-----------------------ESEDLQHSDVEEGEDH--------------------------------------THEECDDD------------------------------------------------------------------------------------------------------------MENNHISEMDPILQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BTF8-1", "uniprot_id": "RALYL_MOUSE", "id": "Q8BTF8-1", "name": "RNA-binding Raly-like protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTGKTQTSNITNKNDPKSINSRVFIGNLNTAIVKKVDIEAIFSKYGKIVGCSVHKGYAFVQYMSERHARAAVAGENARVIAGQPLDINMAGEPKPY-----RPKPGSKRPLSALYRLESKEPFLSV---GGYVFDYDYYRDDFYNRLFDYHGRVPP-PPR----AVIPLKRPRV--AVTTTRRGKGVFSMKGGSRSTVGGSS------------------SSGSKLKSDELQTIKKELTQIKTKIDSLLGRLEKIEKQQKAEA--------EAQKKQLEESIELIQDECVSENAD----------------------HSTEEPAEGGQEADGG--------------------------------------EMTDGVEED-----------------------------------------------------------------------------------------------------------FDEDGGHELFLQIK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AIC1-1", "uniprot_id": "A0A8I6AIC1_RAT", "id": "A0A8I6AIC1-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTGKTQTSNVTNKNDPKSINSRVFIGNLNTAIVKKVDIEAIFSKYGKIVGCSVHKGYAFVQYMSERHARAAVAGENARVIAGQPLDINMAGEPKPY-----RPKPGSKRPLSALYRLESKEPFLSV---GGYVFDYDYYRDDFYNRLFDYHGRVPP-PPR----AVIPLKRPRV--AVTTTRRGKGVFSMKGGSRSSVGGSS------------------SSGSKLKSDELQTIKKELTQIKTKIDSLLGRLEKIEKQQKAEA--------EAQKKQLEESIELIQDECVSENAD----------------------HSTEEPAEGGQEADGG--------------------------------------EMTDGVEED-----------------------------------------------------------------------------------------------------------FDEDGGHELFLQIK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86SE5-1", "uniprot_id": "RALYL_HUMAN", "id": "Q86SE5-1", "name": "RNA-binding Raly-like protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTGKTQTSNVTNKNDPKSINSRVFIGNLNTAIVKKVDIEAIFSKYGKIVGCSVHKGYAFVQYMSERHARAAVAGENARVIAGQPLDINMAGEPKPY-----RPKPGNKRPLSALYRLESKEPFLSV---GGYVFDYDYYRDDFYNRLFDYHGRVPP-PPR----AVIPLKRPRV--AVTTTRRGKGVFSMKGGSRSTASG--------------------STGSKLKSDELQTIKKELTQIKTKIDSLLGRLEKIEKQQKAEA--------EAQKKQLEESLVLIQEECVSEIAD----------------------HSTEEPAEGGPDADGE--------------------------------------EMTDGIEED-----------------------------------------------------------------------------------------------------------FDEDGGHELFLQIK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BB10-1", "uniprot_id": "A0A8M2BB10_DANRE", "id": "A0A8M2BB10-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTGKTQTSNITNKTDPRSLNSRVFIGNLNTAVVKKTDIELIFAKYGKITGCSVHKGFAFVQYACERNARSAVAGENTRVLAGQTLDINMAGEPRPY-----RPKVASKRPFS-LY--------------SGYEFDYDFYRDDFYTRIFDIHGRLAQ-TPR----AVIPIKHSRL--VALSTRRMKYSFQPK---MSTCSSYL------------------KTLSTVKSDQLLTIKQELSQIKIKIDSLLGRLEKIERKQLAEA--------ELHKKHEKAYRSLYLETEKNPGTD----------------------VDGCHQEAGSWEVTD---------------------------------------EGDDGYDER-----------------------------------------------------------------------------------------------------------VNNGLIENHISDVDN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KU81-1", "uniprot_id": "Q7KU81_DROME", "id": "Q7KU81-1", "name": "RRM domain-containing protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLSKLSNQTNSQDPQAVNSRIFVGNLNTFQCSKTDVERMFQIYGRLAGISMHKGYAFVQFTNPFDARNACHGEDGKTVLSQTLDVNMVAEPKAHQIGRKRQNVSKTGNDWDYFYDSYCSSALLRGGGGAGGGGSNGVRAKKRKRLMTNGGGLAVAVQQQQQQHHHSAAAVAAAAAAAVHQQQQQVQQQQQQQHHQQQQQQHQQQVAAVAMAAMANLLPQQQLLLHQQNLLSNAAVATTVTAAPSSIHWSQYKQEQQHHPHAHHPHHQQPFGFQLKSSVAVQATTSPQNAKSAIIANQTALGEPYPVGAAAFAAHQQQHQHQQQHQQPLLQPLTLALSPQQPQPHQAATPLQLHSQLMQQHQHQQQQQQQQQQQQQQHNQQQQHAQEQLSLHQQWGPFKVYSNPDTLICGNCRESFGELSELLDHKKSYCKLRFTCKCQDVAFAASAKTPPTSAKLLCAVCKDAFVNPWDLMVHAQAAHMVNIYELGDDEGSSNSNATTASSNNVANAAVENGHTIADVAATKQQMPQMPDASSTLNKEPNNNNKISNNNIISGAINGHMSPSGTGIIMASVSSAENGMASDMETNCLDIKFSPSASPKEASDMITAAPGSGSHSPVIPLQDQHRDDLSLDGRMSSSSQQTHHSDELNVKLLNGSVSSRGSSPGLEADEPPATRACIVRTLSIETAGSSTAPTANTLSLMSNSLGLALAPQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38996-1", "uniprot_id": "NAB3_YEAST", "id": "P38996-1", "name": "Nuclear polyadenylated RNA-binding protein 3", "aln": "MSDENHNSDVQDIPSPELSVDSNSNENELMNNSSADDGIEFDAPEEEREAEREEENEEQHELEDVNDEEEEDKEEKGEENGEVINTEEEEEEEHQQKGGNDDDDDDNEEEEEEEEDDDDDDDDDDDDEEEEEEEEEEGNDNSSVGSDSAAEDGEDEEDKKDKTKDKEVELRRETLEKEQKDVDEAIKKITREENDNTHFPTNMENVNYDLLQKQVKYIMDSNMLNLPQFQHLPQEEKMSAILAMLNSNSDTALSVPPHDSTISTTASASATSGARSNDQRKPPLSDAQRRMRFPRADLSKPITEEEHDRYAAYLHGENKITEMHNIPPKSRLFIGNLPLKNVSKEDLFRIFSPYGHIMQINIKNAFGFIQFDNPQSVRDAIECESQEMNFGKKLILEVSSSNARP--QFDHGDHGTNSSSTFISSAKRPFQTE-----SGDMYNDDNGAGYKKSRRHTVSCNIFVKRTADRTYAIEVFNRFRDG-TGLETDMIFLKPRMELGKLINDAAYN------------------GVWGVVLVNKTHNVDVQTFYKGSQGETKFDEYISISADDAVAIFN------NIKNNRNNSRPTDYRAMSHQQNIYGAPPLPVPNGPAVGPPPQTNYYQGYSMPPPQQQQQQPYG------------------------------NYGMPPPSHDQGYGSQPPIPMNQSYG----------------------------------------------------------------------------------------RYQTSIPPPPPQQQIPQGYGRYQAGPPPQPPSQTPMDQQQLLSAIQNLPPNVVSNLLSMAQQQQQQPHAQQQLVGLIQSMQGQAPQQQQQQLGGYSSMNSSSPPPMSTNYNGQNISAKPSAPPMSHQPPPPQQQQQQQQQQQQQQQQPAGNNVQSLLDSLAKLQK---------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9U9Q2-1", "uniprot_id": "Q9U9Q2_DROME", "id": "Q9U9Q2-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDPGSAGYNITKDPALAKSRIFLGNLP--VCTREELVSICQPYGKVLGSMVQKNYGFVQFETEELANKAASALHKSTFKQNMLTVRNASIKSKAAN--AIAKRNSNQGGQVTVQGGLVMSAAAAAAGQPLINDCEIIVQNRENTKYAEYIEERLKNSSLRVDVLFPNEDVLLGKVLANISSRGCLYAVLVTPQHEEHNSITVNILYG--------VPAEHRNMPLEDAITLISTDFRLKKQRDAVVLPPSTSIHKGQRRHP--------QEMQGLLERLADNHPLTASQYEVILKYLEGEREEQ----------LKREVGEANALAKLKAP--------------------------------------DPEIELQKKILSIMNKP--------------------------------------------------------------------------------------------------AVTDVTSELMYPTFEAVKEDRRLMELLADDRVLAALESVYNSDLRQILAEYL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :**:*:*** .: :: : **:: ::: :.*:*: .. * : :. . . . . . ", "identical_positions": 11, "similar_positions": 29, "identity": "1.08%" }, { "cls_id": "homologset.agr.SGD:S000006112", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJQ2-1", "uniprot_id": "MINY1_RAT", "id": "Q5BJQ2-1", "name": "Ubiquitin carboxyl-terminal hydrolase MINDY-1", "aln": "------------------------------------------------------------------------------------------MEQPQAECPAPSKTNSAETVESEKHEALSGPEKHPQDKDG------ADAAPEKHPQ----DKDGADAHGEAGKQK--SGDQTLPPVQDGGN-------LECPPPEASSS--PPGPACGIPSEVETTEACSRPQ--QLPQSPRIQQPD---LDFYCVKWIPWKGERTPIITQSSNGPCPLLAIMNILFLQWKVKLPPQKEVITSDELLTHLGNCLLSIKPQEKSEGLQLNFQQNVGDAMTVLPKLATGLDVNVRFTGVSDFEYTPECSVFDLLGVPLYHGWLVDPQSPEAVSAVGKLSYNQLVEKIIICKHSSDS---------NLVTEGLIAEQFLETTAAQLTYHGLCELTATAKEDELSVFFRNNHFSTMTKHKSHLYLLVTDQGFLQEEQVVWESLHNVDG-DSCFCDSDFHLSHSLGK-SHGAEGGSGSPEKQLQVDQDYLIALSLQQQQQ------PQGMLGLSDLELAQQLQQEE-------YQQQQAVQPV--RTRAPSSPGRG----------ATSGRPAGERR-------QRSKTESDCVLL------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q76LS9-1", "uniprot_id": "MINY1_MOUSE", "id": "Q76LS9-1", "name": "Ubiquitin carboxyl-terminal hydrolase MINDY-1", "aln": "------------------------------------------------------------------------------------------MEQPQTENPAPSKATSAETVESENHEALSGP--------------------EKHPQ----DKDGADADGAAGEQE--PGDQTLPPAQDGEN-------LECPPPEASSS--PPGPACGTSPKVETAEVCSRPQ--ELPQSPRIQQPE---LDFYCVKWIPWKGERTPIITQSTNGPCPLLAIMNILFLQWKVKLPPQKEVITSDELLTHLGNCLLSIKPQEKSEGLQLNFQQNVDDAMTVLPKLATGLDVNVRFTGVSDFEYTPECSIFDLLGIPLYHGWLVDPQSPEAVSAVGKLSYNQLVEKIITCKHSSDS---------NLVTEGLVAEQFLETTAAQLTYHGLCELTAAATEDELSVFFRNNHFSTMTKHKSHLYLLVTDQGFLQEEQVVWESLHNVDG-DSCFCDSDFHLSHSLGK-SHGAEGGGGSPEKQLQVDQDYLIALSLQQQQQ------PQGTLGLSDLELAQQLQQEE-------YQQQQAVQPV--RTRAPSPQGRG----------ATSGRPAGERR-------QRSKTESDCVLL------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N5J2-1", "uniprot_id": "MINY1_HUMAN", "id": "Q8N5J2-1", "name": "Ubiquitin carboxyl-terminal hydrolase MINDY-1", "aln": "------------------------------------------------------------------------------------------MEYHQPEDPAPGKAGTAEAVIPENHEVLAGP--------------------DEHPQ----DTDARDADGEARERE--PADQALLPSQCGDN-------LESPLPEASSA--PPGPTLGTLPEVETIRACSMPQ--ELPQSPRTRQPE---PDFYCVKWIPWKGEQTPIITQSTNGPCPLLAIMNILFLQWKVKLPPQKEVITSDELMAHLGNCLLSIKPQEKSEGLQLNFQQNVDDAMTVLPKLATGLDVNVRFTGVSDFEYTPECSVFDLLGIPLYHGWLVDPQSPEAVRAVGKLSYNQLVERIITCKHSSDT---------NLVTEGLIAEQFLETTAAQLTYHGLCELTAAAKEGELSVFFRNNHFSTMTKHKSHLYLLVTDQGFLQEEQVVWESLHNVDG-DSCFCDSDFHLSHSLGK-GPGAEGGSGSPETQLQVDQDYLIALSLQQQQ-------PRGPLGLTDLELAQQLQQEE-------YQQQQAAQPVRMRTRVLSLQGRG----------ATSGRPAGERR-------QRPKHESDCILL------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KQS4-1", "uniprot_id": "MINY1_DANRE", "id": "A3KQS4-1", "name": "Ubiquitin carboxyl-terminal hydrolase MINDY-1", "aln": "-------------------------------------------------------MADSCADTVDGEIKG------FSEGQQLNITKNEDLEQTKPQKEAIANTEESSACVSQIKQDLAPCKDPP---TT------TTASLEDDAK----ATSSASVTSKSQDESEVINSQSYTPSQSEATPSFSMASLEFSEENNGVP--PDGPLSSAKSARDGNQVSVQEN--EGAVAGAMRPAEPTMPAYYFVKWITWKEKKTAVITQSENGPCPLIAIMNILLLRWKVKFPAQTEVVTTEELMAHLGECVLSIKPREKAEGMELNFQQNMSDAMAVLPKLSTGLDVNVRFTGVSDFEYTPECIVFDLLDIPLYHGWLVDPQSPEVVSAVGKLSYNQLVEKIIEFKHSTDS---------SQVSEGLIAEQFLESTATQLSYHGLCELNTTAKEGELSVFFRNNHFSTMIKHKGHLYLLVTDQGFLQEESVVWESLHNVEG-DGNFCDSDFRLCHPSQKPSAAAAQPSTQQQQQMQIDQDYLVAMSLQQEQ-------GEAPGPLSDLELARQLQQEE-------YQQPQTQQQQ--QQQPSAGQMRG----------QATSPQGGQRR-------REKKEETDCCIL------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6PDI6-1", "uniprot_id": "MINY2_MOUSE", "id": "Q6PDI6-1", "name": "Ubiquitin carboxyl-terminal hydrolase MINDY-2", "aln": "MENSPDSPQPLELGVAAGRVS----PPEGRRRGGREAEDGPAGRAVD-SGGQGAAAAAARSSLGDPTSPS-------QLGCGAGSDLKDGASSSPAASEVPSRGQHKVTASPELAEAAAGRGSGPVGDT-------GTCRVEQAAE---EPSSTGAPSSSCSEPSPPGDSPSLDSLESFSNLHSFPSSSEFNSEEGAETRVPEDVEEGAAGPPRAAPLCKEEE-EDPAQVLAASKERFPGQSVYHIKWIQWKEENTPIITQNENGPCPLLAILNVLLLAWKVKLPPMMEIITAEQLMEYLGDYMLEAKPKEISEIQRVNYEQNMSDAMAILHKLQTGLDVNVRFTGVRVFEYTPECIVFDLLDIPLYHGWLVDPQIDDIVKAVGNCSYNQLVEKIISCKQSDNS---------QLVSEGFVAEQFLNNTATQLTYHGLCELTSTVQEGELCVFFRNNHFSTMTKYKGQLYLLVTDQGFLTEEKIVWESLHNVDG-DGNFCDSEFHLRPPSDP-------ETVYKGQQDQIDQDYLMALSLQQEQQSQEINWEQIPEGISDLELAKKLQEEEDRRASQYYQEQEQAQAVVTTTTPSTQAQQGQPAQASPSSIKQPGNSERKRKEPREKDKEKEKEKNSCVIL------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M6W4-1", "uniprot_id": "A0ABK0M6W4_RAT", "id": "A0ABK0M6W4-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "MENGPDSPQPLELGVPAGRVS----TPEGRRRDGREAEDGPAGRAVD-SGGQG--AAAARSSLGDPTSPS-------QHGCSAGSDLKNSASSSPVASEAPSRGQHKVTASPELAEAAAGRGSGPVGDT-------GTCRVEQAAE---EPSSAGALSSSCSEPSPPGDSPSLDSLESFSNLHSFPSSSEFNSEEGAETRVPEDVEEGAAEPPRVAPLCKEEE-EDPAQVLAASKERFPGQSVYHIKWIQWKEENTPIITQNENGPCPLLAILNVLLLAWKVKLPPMMEIITAEQLMEYLGDYMLEAKPKEISEIQRVNYEQNMSDAMAILHKLQTGLDVNVRFTGVRVFEYTPECIVFDLLDIPLYHGWLVDPQIDDIVRAVGNCSYNQLVEKIISCKQSDNS---------QLVSEGFVAEQFLNNTATQLTYHGLCELTSTVQEGELCVFFRNNHFSTMTKYKGQLYLLVTDQGFLTEEKIVWESLHNVDG-DGNFCDSEFRLRPPSDP-------ETVYKGQQDQIDQDYLMALSLQQEQQSQDINWEQIPEGISDLELAKKLQEEEDRRASQYYQEQEQAQAAVATTTPSTQAQRSCCCCLLSSSLSRAIRSASLRRSFRHTGMNQTQSKDRRCLCPDHIIQDKKTRITTFAMYQEVICL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NBR6-1", "uniprot_id": "MINY2_HUMAN", "id": "Q8NBR6-1", "name": "Ubiquitin carboxyl-terminal hydrolase MINDY-2", "aln": "MESSPESLQPLEHGVAAGPASGTGSSQEGLQETRLAAGDGPGVWAAETSGGNGLGAAAARRSLPDSASPAGSPEVPGPCSSSAGLDLKDSGLESPAAAEAPLRGQYKVTASPETAVAGVGHELGTAGDAGARPDLAGTCQAELTAAGSEEPSSAGGLSSSCSDPSPPGESPSLDSLESFSNLHSFPSSCEFNSEEGAENRVPEE-EEGAAVLPGAVPLCKEEEGEETAQVLAASKERFPGQSVYHIKWIQWKEENTPIITQNENGPCPLLAILNVLLLAWKVKLPPMMEIITAEQLMEYLGDYMLDAKPKEISEIQRLNYEQNMSDAMAILHKLQTGLDVNVRFTGVRVFEYTPECIVFDLLDIPLYHGWLVDPQIDDIVKAVGNCSYNQLVEKIISCKQSDNS---------ELVSEGFVAEQFLNNTATQLTYHGLCELTSTVQEGELCVFFRNNHFSTMTKYKGQLYLLVTDQGFLTEEKVVWESLHNVDG-DGNFCDSEFHLRPPSDP-------ETVYKGQQDQIDQDYLMALSLQQEQQSQEINWEQIPEGISDLELAKKLQEEEDRRASQYYQEQEQAAAAAAAAS--TQAQQGQPAQASPSSGRQSGNSERKRKEPREKDKEKEKEKNSCVIL------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08930-1", "uniprot_id": "YP191_YEAST", "id": "Q08930-1", "name": "Ubiquitin carboxyl-terminal hydrolase MIY1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDLSFTTKSVKINGQNHRILLQNENGPCALLALANILILSPDHTRFSN-ELIRLVNKGSQISLKELIEVLADIALQVTDKPSTDISELLSLLPRLHEGLNINPEFNGS--FENTKEMSIFRLFNVDVVHGWVINSFINENIDEKLSHYSYESAQRILTQAADINCGISQDENSDEVLRDAMHLGLFLNESPTQLTAFGLLRLREKLLHNKFSILFRNDHFSTLFKYEDRLYTLVTDFGYKNCKDIVWQSLDSVDGSCDAFFAGNFSAAEVNGQ--------QLSTDIERDFGTGNLLLEEIQQIEN--------------DKELAKQLQEQE----------QERVTKFEAKRKIHSHKKNSE-------IHAPVKKDKFKRRSSLLNAKASEKEKSECVVM------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : : :. :: *. ****.*:*: *:*:* . . . *:: : :. * : : : . ::.: :::* :* **::* .*.* ** * * :* *:.: : ***:::. : : . : .::*: . : . : :.: **: :.:**: .** .* ..::.::***:****: *::.:** **** *: :.:**:**..*:* . * .:* : :.. . *: .:** : * ***::**::* : : .. *: : : : ", "identical_positions": 71, "similar_positions": 113, "identity": "10.68%" }, { "cls_id": "homologset.agr.SGD:S000006116", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DFK6-1", "uniprot_id": "B5DFK6_RAT", "id": "B5DFK6-1", "name": "AP-3 complex subunit delta-1", "aln": "--------MALKMVKG-SIDRMFDKNLQDLVRGIRNH---KEDEAKYISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKRVGYLAASQCFHEGTDVIMLTTNQIRKDLSSPSQ---YDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEG---------------------TTYRDELLTKIIDICSQSNYQHITNFEWYISILVELTRLEG----TRHGHLIAAQMLDVAIRVKAIRKFAVSQMSSLLDSAHLVASSTQRNGICEVLYAAAWICGEFSEHLQGPQQTLEAMLRPKVTTLPGHIQAVYVQNVVKLYASILQQKEQAADTEGAQEVTQLLVERLPQFVQSADLEVQERASCILQLVKHVQKLQAK------------------GVPVAEEVSALFAG-ELNPVAPKAQKKVPVPEGLDLDAWINEPP-----SDSESEDEKPKAIFHEEEP------RHTRRRQPEEDEEELARRREARKQEQANNPFYIKSSPSPQ--KRYQDAPGVEHIPVVQIDLSVP----LKVPGMPMSDQYVKLEEQRRHRQRLEKDKKRKKKE----KGKRRHSSLPTESDEDIAPAQRVDIITEEMPENALPSDEDDKD----PNDPYRALDIDLD--------KPLADSEKLPVQKHRNAETVKSPEKEG-----VPGVEKKSKKPKKKEKKPKERERE--KKDKKGE-------------------------------------DLDFWLSTTPPPAAAPVPAPSTEGLAASIVTPPKGECEVLKGEEPQDEEDHMDHDQERKSSRHKKKKHRKEKE--ERPRDKKKAKRKQVVQLEN-GAPAEEEEEE-EEPIPPMSSYCLLAENPYIKVT-------YDVQASLQKDSQVTVSIILENQSSSFLKNMELNVLDSLNTKMARPEGSSVHDGVPVPFQLPPGVSNEAQFVFTIQSIVMAQKLKGTLSFIAKDDEGATHEKLDFRLHFSCSSYLITTPCYSDAFAKLLESGDLSMNSIKVDGISISFQNLLAKICFYHHFSVVERVDSCASMYSRSIQGHHVCLLVKKGESSVSVDGKCSDATLLSSLLEEMKTTLSQC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54774-1", "uniprot_id": "AP3D1_MOUSE", "id": "O54774-1", "name": "AP-3 complex subunit delta-1", "aln": "--------MALKMVKG-SIDRMFDKNLQDLVRGIRNH---KEDEAKYISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKRVGYLAASQCFHEGTDVIMLTTNQIRKDLSSPSQ---YDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEG---------------------TTYRDELLTKIIDICSQSNYQHITNFEWYISILVELTRLEG----TRHGHLIAAQMLDVAIRVKAIRKFAVSQMSSLLDSAHLVASSTQRNGICEVLYAAAWICGEFSEHLQGPQQTLEAMLRPKVTTLPGHIQAVYVQNVVKLYASILQQKEQAADTEAAQEVTQLLVERLPQFVQSADLEVQERASCILQLVKHVQKLQAK------------------GVPVAEEVSALFAG-ELNPVAPKAQKKVPVPEGLDLDAWINEPP-----SDSESEDEKPKAIFHEEEP------RHTRRRQPEEDEEELARRREARKQEQANNPFYIKSSPSPQ--KRYQDAPGVEHIPVVQIDLSVP----LKVPGMPMSDQYVKLEEQRRHRQRLEKDKKRKKKE----KGKRRHSSLPTESDEDIAPAQRVDIITEEMPENALPSDEDDKD----PNDPYRALDIDLD--------KPLADSEKLPVQKHRNAEAVKSPEKEG-----VLGVEKKSKKPKKKEKKTKERERE--KKDKKGE-------------------------------------DLDFWLSTTPPPAAAPIPAPSTEELAASTITSPKDECEVLKGEE----EDHVDHDQERKSSRHKKKKHRKEKEKEERPRDKKKAKKKQVAPLEN-GAAAEEE----EEPIPPMSSYCLLAESPYIKVT-------YDIQASLQKDSQVTVSIILENQSSSFLKNMELNVLDSLNTKMTRPEGSSVHDGVPVPFQLPPGVSNEAQFVFTIQSIVMAQKLKGTLSFIAKDDEGATHEKLDFRLHFSCSSYLITTPCYSDAFAKLLESGDLSMNSIKVDGISMSFQNLLAKICFYHHFSVVERVDSCASMYSRSIQGHHVCLLVKKGESSVSVDGKCSDATLLSSLLEEMKTTLAQC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14617-1", "uniprot_id": "AP3D1_HUMAN", "id": "O14617-1", "name": "AP-3 complex subunit delta-1", "aln": "--------MALKMVKG-SIDRMFDKNLQDLVRGIRNH---KEDEAKYISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKRIGYLAASQSFHEGTDVIMLTTNQIRKDLSSPSQ---YDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEG---------------------TTYRDELLTKIIDICSQSNYQYITNFEWYISILVELTRLEG----TRHGHLIAAQMLDVAIRVKAIRKFAVSQMSALLDSAHLLASSTQRNGICEVLYAAAWICGEFSEHLQEPHHTLEAMLRPRVTTLPGHIQAVYVQNVVKLYASILQQKEQAGEAEGAQAVTQLMVDRLPQFVQSADLEVQERASCILQLVKHIQKLQAK------------------DVPVAEEVSALFAG-ELNPVAPKAQKKVPVPEGLDLDAWINEPL-----SDSESEDERPRAVFHEEEQ------RRPKHRPSEADEEELARRREARKQEQANNPFYIKSSPSPQ--KRYQDTPGVEHIPVVQIDLSVP----LKVPGLPMSDQYVKLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVDIVTEEMPENALPSDEDDKD----PNDPYRALDIDLD--------KPLADSEKLPIQKHRNTETSKSPEKD------VPMVEKKSKKPKKKEKKHKEKERD--KEKKK--------------------------------------------------------------------------------------------EKEKKKSPKPKKKKHRKEKE--ERTKGKKKSKKQPPGSEEAAGEPVQNGAPE-EEQLPPESSYSLLAENSYVKMT-------CDIRGSLQEDSQVTVAIVLENRSSSILKGMELSVLDSLNARMARPQGSSVHDGVPVPFQLPPGVSNEAQYVFTIQSIVMAQKLKGTLSFIAKNDEGATHEKLDFRLHFSCSSYLITTPCYSDAFAKLLESGDLSMSSIKVDGIRMSFQNLLAKICFHHHFSVVERVDSCASMYSRSIQGHHVCLLVKKGENSVSVDGKCSDSTLLSNLLEEMKATLAKC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AM99-1", "uniprot_id": "A0A8M3AM99_DANRE", "id": "A0A8M3AM99-1", "name": "AP-3 complex subunit delta-1", "aln": "--------MALKIVKG-SIDRMFDKNLQDLVRGIRNH---KEDEAKYISTCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDVSWAAFNIVEVMSSSKFTYKRIGYLAASQCFHEGTDVIMLTTNQIRKDLSSPNQ---YDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMLHVDKAEG---------------------TTYRDELLTKIIDICSQSNYQYITNFEWYISILVELTRLEG----TRHGHLIASQMLDVAIRVKAIRAFAVAQMATLLDNAHLLTGNTQRNGICEVLYAAAWICGEFAEHLEDPMLTLEAMLRPKVATLPGHIQAVYVQNAAKLFATVLQKHEGETDSQAAQETSQLLIDRLPLFVQSANLEVQERASCILQLVKYIQKLQQK------------------NVEVAEEVTALFAG-ELNPVAPKAQKKVPIPEGLDLDAWINEPP-----SESESEDEKPKAVFAKEEP------KHSRSRHTEVDEKELARRREARKQEQANNPFYIKASPSSQ--KVY-DAPGVEHIPVVQIDLSVP----LKVPGMPMSDQYVKLEEERRQKEKADKKKKEKKKK-REKRGKGRKGDSGPESEEDITPAHHVDIVTEEMPENALPSDDDDKD----PNDPHKALDIDLDNLLSGAGSRPLADSEKLPVRTHR-PEVLKSPAEDRDDNTIPQETKKKSSKDKKEKKKDKEKDRKRSKEDKKKKKKHKDVEEELPESLPEEVVQSEETKEVAVPPTSADASDLDFWLSSAPVPPVAQVVTVSSSAAAATVDSSSAAAAESEPEE------LKDTEPDDTKSSKHKKKKQKKEKEEKEKKKKKRHHHHHHHHSDAGAEDSVQNGTVEDEEPLPPMSNYSLLAENSYIKMMKEDADQVCDIQGNHQDESKVVVSVIFENKSDSFLKSMEFNVLDSLNSKLQRPDGAGPHDGLTVPFQLPPGVSNEARFVFSVQSIVMPQKLKGTLTFIVKTDESSTHEKLDFKLHFTCTSYLITTPCYSDAYAKLLESGDLKGSSLRLEGVNMPFHHLLARICFHHHFSVVERIDSCASMYSRSIQGHHVCLLVKSSDQTVSIDAKCDEPSLLGNVLDEIKQTFSKC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P54362-1", "uniprot_id": "AP3D_DROME", "id": "P54362-1", "name": "AP-3 complex subunit delta", "aln": "--------MALKKVKGNFFERMFDKNLTDLVRGIRNN---KDNEAKYISTCIEEIKQELRQDNISVKCNAVAKLTYIQMLGYDISWAGFNIIEVMSSSRFTCKRIGYLAASQCFHPDSELLMLTTNMIRKDLNSQNQ---YDAGVALSGLSCFISPDLSRDLANDIMTLMSSTKPYLRMKAVLMMYKVFLRYPEALRPAFPKLKEKLEDPDPGVQSAAVNVICELARKNPKNYLPLAPIFFKLMTTSTNNWMLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECINTVIAVLISISSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQAHKDLILACLDDKDESIRLRALDLLYGMVSKKNLMEIVKRLLGHMERAEG---------------------SAYRDELLYKVIEICAQSSYLYVTNFEWYLTVLVELIQLEAG---SRHGRLIAEQLLDVAIRVPVVRQFAVNEMTNLLD---TFTVSAQSNSMYEVLYAAAWIVGEFAGELEDAEKTLNILLRPRL--LPGHIQGVYVQNVIKLFARLATTCLELQDLPGLVTLCDHVLDKLQHFNGSSDIEVQERANSACMLIEMLRNQLSTSTDAMAMDTTTEGGIPPLAIEIVQEMTLLFTG-ELIPVAPKAQRKVPLPDGLDLDEWINAPPPEDAASSSSSEHDKDELFVSATQAGTGADGGEKRRQSLELTPEQLERQRMARLIEQSNNPHYLKSTPTASGASNADQYDNIDDIPITELPLDMEGVAALRVGITKRSDKYLQEQQAAQGSKDGKKKHKKGKKS---KKAKNKVAYNSSSESEGEPKPLHIVNTTLDMPEGVSMSDSEDKDGKYDPNDPHRALDIELD----------ITEFEAPAVRSASKKSAADKENLKT-----PADLAGGGNAAKKDRKKDKDKDKE-----------------------------------------------------------------------------------------------------------RKVKREHR------ESKRERKEAAVQPVIDLIDADTPTPSP--------------SHISAT---------------------SNNNNTSTVLPDAPKHHKKKKNKEKTTDEAPDALATATGSSIID-----------VGGEE--ASEVASKVHKKKHK--------KEKSQRKEKK--------------KASESASVSAIVSIGDYEQP----LGISTPSKEIL--------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08951-1", "uniprot_id": "AP3D_YEAST", "id": "Q08951-1", "name": "AP-3 complex subunit delta", "aln": "MTSLYAPGAEDIRQRLRPFGFFFEKSLKDLIKGIRSHNETPEKLDQFFKQVLSECREEVNSPDLNSKTNAVLKLTYLEMYGFDMAWCNFHILEVMSSNKLQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDGNNDVVKVGIALSGLSTIITPSLARDIADDLFTMLNSTRPYIRKKAITALFKVFLQYPEALRDNFDKFVSKLDDDDISVVSAAVSVICELSKKNPQPFIQLSPLLYEILVTIDNNWIIIRLLKLFTNLSQVEPKLRAKLLPKILELMESTVATSVIYESVNCIVKGNMLEED----DFETAMACLERLHTFCDSQDPNLRYISCILFYKIGKINTDFISRFDQLIIRLLSDVDVSIRSKAIELVEGIVDEDNLKAIVQTLMKQFVDEDVVILQTGSIVYEKSKRIPIIIPENYKIKMVNVIISICSADNYSSVNDFEWYNAVIMDLAMLCQDISDKSLGSKIGEQFRNLMIKVPSMREVTIANIIKLIS------NDNINKQLPTVLRECIWCLGEFSTLVENGN-DLIKIMTENISYYSHSVQEVLILALVKVFSNWCNN-FQEDKRFEIKMVLKELIEFFENLSYSSTFEVQERSVEVLEFLRLSLEALEEDTEG-------------LPMLLSEVLPSFFNAYELAPIARGTQLKLAVDENLDLETPFLTKEA----ADELLDEQKSDAISDLMSD-----ISMDEQVELKFVDDSDTSYEEKEKLDDFENPFEIEREKERMSNPYYLGEEDEERT--------------------KNSKDLLDLNEEESSDKKPETIRLNRTDN-----SLNSLSLSTTEISRKKKKGKKKNRVQVLSDEPVIEAAPKRKDAFQKPHDNHSTQNPLKK--------------DKINLRMHSQLENFDFSNFGQ------SSNAGRGSQEEGNLRKEDELELS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLEANLIVKDEKDNLSDTEEVIVIKKKKKGKKSKSKN----------------------------------------------------------------KLKTKAKNSPEPNEFLRDQSTDI------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :*:*.* **::***.: :. :::. :.* ::*:.. :: * *** ****::* *:*::*. *:*:****:.:: **:*******.*: .::::**:** ::***. .: ..*:**:*** :::*.*:**:*:*::*::. *:**:* **: ::****:***:** * :: .**:* * .* ****.*****:::**: :: *:*::::::.: ***::*:::*** *: :**:* **: : :*:.** * *::**.:* :: : .. . : *:::*: : :..* **:*:. : : ** * :.. :. ..:**: *.* * *** :*::*: *:*.:.** **: *: :. : *: ::: :*.**: ..* :.:**** :::::* * . * *. *: :: *:* :* .:: :: *:. . : : ** . * ***: :: * :: .: . :* * : *::: . . ::: : : *: :*****: ::. : : : : :. :* . ** *:* :* *:.: :.***: : :.. :.:: . . . : .. . . :: :**. :: . : *.. :. :: : .. : . . . . . .. .. : * . : . ** *:* : : : . : :: . . .. : . :* .: : . . :: . . . : . .. .. * :: . . ", "identical_positions": 193, "similar_positions": 313, "identity": "14.29%" }, { "cls_id": "homologset.agr.SGD:S000006117", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQ38-1", "uniprot_id": "D3ZQ38_RAT", "id": "D3ZQ38-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKGRQWRYTQ-----------------LPTEMEDT----------------LSGEEG--------------EEEEEEE-----------------------------------------------------------------------PAPAPQDP-VEPQLTEASQVLGASEIKQLSLHLPPRVTGH-PWNLIFCTSRDGFSLQRLYRQMEGHSG-----PVLLLLRDQDGQMFGAFSSSALRLSKG--FYGTGETFLFSFSPQ-----------------------------LKVFKWTGHNSFFVKGDLDSLMMGSGSGQFGLWLDGDLYHGGSYPCATFNNEVLARR-EQFCIRELEAWALS-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2ACG1-1", "uniprot_id": "TLDC2_MOUSE", "id": "A2ACG1-1", "name": "TLD domain-containing protein 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDT----------------LSGEEG--------------EEEEEEEPA---------------------------------------------------------------------PAPAPQDP-VEPQLTEASQVLGASEIKQLSLHLPPRVTGH-PWSLVFCTSRDGFSLRRLYRQMEGHSG-----PVLLLLRDQDGQMFGAFSSSAIRLSKG--FYGTGETFLFSFSPQ-----------------------------LKVFKWTGHNSFFVKGDLDSLMMGSGSGQFGLWLDGDLYHGGSYPCATFNNEVLARR-EQFCIKELEAWVLS-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0PJX2-1", "uniprot_id": "TLDC2_HUMAN", "id": "A0PJX2-1", "name": "TLD domain-containing protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRGLRWRYTR-----------------LPSQVEDT----------------LSGEEGN-------------EEEEEEEAAPD-------------------------------------------------------------------PAAAPEDP-TVPQLTEASQVLSASEIRQLSFHFPPRVTGH-PWSLVFCTSRDGFSLQSLYRRMEGCSG-----PVLLVLRDQDGQIFGAFSSSAIRLSKG--FYGTGETFLFSFSPQ-----------------------------LKVFKWTGSNSFFVKGDLDSLMMGSGSGRFGLWLDGDLFRGGSSPCPTFNNEVLARQ-EQFCIQELEAWLLS-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B4Y3-1", "uniprot_id": "A0A8M2B4Y3_DANRE", "id": "A0A8M2B4Y3-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDHRAPRDKSRASYFGNVKNRLGSKLPAGISQTPGFISAQCSIGAPGAMGRSV--------------GQEGVKGHHHIRNPKLRQYYLKEAAFPAKD--------------------------------PTMKTLALCTNNEDGLPKKKASTSSPTASVPSLNPSLDTCVVG-----------------------TATLVSPSTD-----------AEYDKLTDVEAVPLPDGNVCL--------LALPSECSQGEDPAGLSCLKLFSRYITDRKGVVSGILLVTSSKIFFDPQKSHPLVQENGCEEYVFSCPVDDLASVSFYTDISHVYFSKTTY---------------------------------------------------------------------------------------RCNSSKT----------------------------------------------------------SKSKTHSNKKPHHS------------ALEDIPAPDSCDPTAAPSAKAEVEDEESGETGDMADAERQLTLQSGGMLTAAATFC---------------------------------------------CGGPDSVQRGNNPFEHSD-------------------------------------------------------------------------KTQQQ--------------------------------------------SYWERQLLADPCTSTS----------------------------------------NCGINGSLMFVRIRQKLQHGKKRAFSKSKIASRDA--------WFTMQQERSDELYAYLSQHRPDLCILEGDEEDEAERDEEDFVLLDEEEQEEEDESPR------------ASHTGEDWEIVS------------------------------------AEESALKAPGSTEPDSLSYILSQSVILDAQQVKEISRELPPRTIGY-TWQLSYSTDKHGASLKTLYRKLSATDS-----PVLILIKDHNQQVFGSFLSHPLHPSDA--FYGTGETFLFLSHPR-----------------------------FKCFKWTGENSFFIKGDLDSFAIGGGSGHFGLWVDERLFLGRSSPCFTFNNCSLSET-NDFTILDLEAWTFG-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q4KMM3-1", "uniprot_id": "OXR1_MOUSE", "id": "Q4KMM3-1", "name": "Oxidation resistance protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVSNLSWLKKKS-QSVDITAPGFNPLGGAGKQAPQASKPPAPKTPIIEEEQNNSANTQKHPS------RKSELKRFYTIDTGQKKTLDKKDGRRMSFQ--------------------------------KPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAVVTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSE-----------AEFDKTTTPDVAHPKEAPPAS-TVSGIRPARVVSSTSEEEEAFTEKFLKINCKYITIGKGTVSGVLLVTPNNIMFDPHKTDPLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKIKESLP------------------------------------------------------------------------------------IELDQLSGRGSCHSKKATGVSAEDADPRAR--------------------------------------DQGNDSASTAPR-STEES--------LSEDAFTESELSPIREELLSS-EPRQE-KSSDASSESVQTVSQMEVQSLTATSEAANVPDRTSSNPG-------ALSHETGLSGLETATKGGDKATESLQEVSGPKEQSTEVKGQDNQD-----------SSHQESSLQQEAGE-DSVSSGETVELKEKPAVLKDQQGQELKRDSETEVEELRKLWKTHSMQQAKQQ--------------------------------------------RDTIQQVSQRESKHSS------------AAADAHG--------------EGSSLLKEKRRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFIQWSPE---IYAEDSGEYTREPGFIVVKKMDESEANEAP-A------------GEAAAREWEVVSVAEYHRRIDALNTEELRTLCRRLQ----ITTREDINSKQVAPAKADLEPESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGY-PWTLVYGTGKHGTSLKTLYRTMTGLDT-----PVLMVIKDSDGQVFGALASEPFKVSDG--FYGTGETFVFTFCPE-----------------------------FEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNHTLSKK-EDFFIQDIEIWAFE-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V8B0-1", "uniprot_id": "OXR1_RAT", "id": "Q4V8B0-1", "name": "Oxidation resistance protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDYLTTFTGKSGRLLRGTASRLWGLGGGG-EARQVRFEDYLREPAPGD-PGCGPGELRPPS------PTSPEG----PDTGQKKTLDKKDGRRMSFQ--------------------------------KPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAVVTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSE-----------AEFDKTTTPDVVHPKEAPPSS-TESSIRPARVVSSTSEEEEAFTEKFLKINCKYITNGKGTVSGVLLVTPNNIMFDPHKTDPLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKLKESLP------------------------------------------------------------------------------------IEVDQLSGRGFCHSKKMTGVPAEETDSRSR--------------------------------------DQGNDSVSTAPR-STEES--------LSEDVFTESELSPIREELPSS-ELRQE-KSSDASSESVQTVSQIEVESLTAASESADVPDHTNANSGRSSSEVGALSHETGLSSLEIATKEGDKATGNLQEVSGPKEQSTDIKGQDNQD-----------SFHHENSLQQEAGE-DSLSSGETVELTEKPTVLKDQQGKELKRDSETEVEELRKLWKTHSMQQAKQQ--------------------------------------------RDTIQQVAQRESKHRG------------APADAHG--------------EGSSLLKEKRRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFIQWSPE---IYAEDTGEYTREPGFIVVKKMAESGPDEAP-A------------GEAAAREWEIT-------------------------------TREDINSKQAAPAKADLEPESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGY-PWTLVYGTGKHGTSLKTLYRTMTGLDT-----PVLMVIKDSDGQVFGALASEPFKVSDG--FYGTGETFVFTFCPE-----------------------------FEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNHTLSKK-EDFFIQDIEIWAFE-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N573-1", "uniprot_id": "OXR1_HUMAN", "id": "Q8N573-1", "name": "Oxidation resistance protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTKDKNSPGLKKKSQSVDINAPGFNPLAGAGKQTPQASKPPAPKTPIIEEEQNNAANTQKHPS------RRSELKRFYTIDTGQKKTLDKKDGRRMSFQ--------------------------------KPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAVVTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSE-----------AEFDKTTNPD-VHPTEATPSS-TFTGIRPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIMFDPHKNDPLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKIKESLP------------------------------------------------------------------------------------IDIDQLSGRDFCHSKKMTGSNTEEIDSRIR--------------------------------------DAGNDSASTAPR-STEES--------LSEDVFTESELSPIREELVSSDELRQD-KSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKE-DQIADNFQGISGPKEDSTSIKGNSDQD-----------SFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQ--------------------------------------------RENIQQVSQKEAKHKI------------TSADGHI--------------ESSALLKEKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFIQWSPE---IYAEDTGEYTREPGFIVVKKIEESETIEDS-S------------NQAAAREWEVVSVAEYHRRIDALNTEELRTLCRRLQ----ITTREDINSKQVATVKADLESESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGY-PWTLVYGTGKHGTSLKTLYRTMTGLDT-----PVLMVIKDSDGQVFGALASEPLKVSDG--FYGTGETFVFTFCPE-----------------------------FEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKK-EDFFIQDIEIWAFE-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PD70-1", "uniprot_id": "OXR1A_DANRE", "id": "A0A8M9PD70-1", "name": "Oxidation resistance protein 1A", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPLQHTPRLKKKSQSVDIGSQGFPARLIPSLSLNRSS-PPAAKTNTSEVQENNTTNAQRRVP------RCSDLKRGYTIDTGQKKTPEKKDGRRMSFQ--------------------------------RPKGTIEYSVESRDTLNNIALKFDTTPNELVQLNKLFSRNVVPGQVLYVPDPEYVSSAGSSPSFSPSSPLSPTSSE-----------ADLEKVTTDSNGPPRSDAPAPPVLSALRSSRVVSSTSEEEEALTEKFLKINCKYITDGKGVVSGVLLVTPNNIMFDPHRTDPLVLEKGCEEYGIMCPLEEVQSAAVYKEIIDSKIRDSVT------------------------------------------------------------------------------------DLEAVFS-----------------SFSHQT--------------------------------------DQRYDSASTAPR-STEGS--------FSEDVFTESELSPIREEHQSTEELQQEDKSSGASSQSVKTLLQ-EPQSHTEEKDNDGEPAG---------------------------------------DTAKPIQD--EPTSRDHQQ-----------TPHCQTEGEPAAQE----SSAEGVKLT-----------RDGTRDSETDVEELRKMCKTHTMQQAKEQ--------------------------------------------RESVQQAQRESEQQTT------------EQSQRLS--------------SAEGPVVSKERQKSHKFLCLRVGKAMKKTFVSNASASMQQYAQRDRKHEYWFAVPQERSDHLYVFFIQWSPD---VFGDGLGSISRDPGFIVVKKIEESEANEEQQP------------EENSEKEWEVVSWTEYHRRIDALNSEDLRSLCKRLQ----ITTKEDVNSKHGTSITASLEPETFKPNLNEPSDLLEAEQIEKLAKHLPPRTIGY-PWNLAFSTSKHGMSIKTLYRAMQDQDS-----PMLLVIKDSDGQIFGALASEPFKVSEG--FYGTGETFLFTFYPE-----------------------------FEAYKWTGDNLFFIKGDMDSLAFGGGSGEFGLWLDGDLYHGRNHSCKTFGNPMLSMK-EDFFVQDIEIWSFE-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6DFV7-1", "uniprot_id": "NCOA7_MOUSE", "id": "Q6DFV7-1", "name": "Nuclear receptor coactivator 7", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDTKEEKKEQKERKQSYFARLKKKKQAKQNAEIVSAASSKSRSGKDDANSDILEQDKFNVTAEGDHSTDDKKKRKSNQLKEIRRTELKRYYSVDDNQNKTHDKKE-KKMMVQ--------------------------------KPQGTMEYTAGSQDTLNSVALKFNVTPNKLVELNKLFTHTIVPGQVLFVPDANISSSTIQLSSSTPGATVSPSSSD-----------AEYDKLPDADLARKALKPIER----------VLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYSDISHMKIKDALPSDLPRDL----------------------------------------------------------------------CPLYRPGEWEDLASEKDINPFSKFKSINKEKRQQNGERTLALDAKSVRSPEESTERTCTRIEPPDNSELWKLKNLQSSRGTTSESPS-VTQLS-----MRAALEPTAKENCLLKGDEDFVDLEELSSQPESGINKGDATKECLSYD---QKKDGPHTVMSAKKGHVQS-AQEVMGPESDTELKGALDLETAEKQDEAPEVDKHSGSPENLGESTLNIHEDLDKIKLIEFYLNKNKEGSQLLENVQKSELSDRKSIEPGGIDITLSSSLPQAGDSPPEDNKEPGTLWVKGGETLPLKLD--------------------------------------------PSAEETVINNKEVLDS-LGSSLDKMCHSAQMDNKSEIQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFASHTATMVQQYSKRRKQPEYWFAVPRERVDHLYTFFVQWSPD---VYGKD----AKEQGFVVVEKEELN--MIDNFF------------SEPTTKSWEIITVEEAKRR-----------------------------KSTCSYYEEEEEEEEGLPILQPHSALLENMHIEQLARRLPARVQGY-PWRLAYSTLEHGTSLKTLYRKSASLDS-----PVLLVIKDMDNQIFGAYATHPFKFSDH--YYGTGETFLYTFSPN-----------------------------FKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKK-EDFIVQDLEVWTFE-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LWN1-1", "uniprot_id": "F1LWN1_RAT", "id": "F1LWN1-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDTKEEKKEPKERKQSYFARLKKKKQAKQNAEIVSAARSHS--GKDDSHSVILEQDKSNIAAEGDQSTDEKKKRKNNQLKEIRRMELKRYYNADDNQSKSHDKKE-KKMVVQ--------------------------------KPQGTLEYTAGSQDTLNSVALKFNVTPNRLVELNKLFTHTIVPGQVLFVPDANIPSSTLRLSSSTPGATVSPSSSD-----------AEYDKLPDADLARKALKPIER----------VLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSDLPRDV----------------------------------------------------------------------CPLYRPGEWEDLASEKDINPFSKFKSINKEKRQQNGERTLALDVKSVGSPEESTERMRTRTEPPDDSESWKLKNLEYSRGTASEFPS-VTQLSKGPSSVCAALEPTAKENRLL-GDEDFVDLEELSSQPGSGMDKGDARKECLPYD---QKKDAPQTIMSAKKGEEQS-APDVTGTESDAELKGALDSETGEKQDEAPEVDKQSGSPENWRESTLSIHEDLDKVKLIEFYLNKNKEGSQLSENVLKSELSERKSIEPDGIDITLSSSLPQAGDSPPESHKEPGTLCVKGGGTPPPKLH--------------------------------------------PSAEETVTNNKEALDS-LESSLDKLCQGAQMDNRSEIQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFASHSTTMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPD---VYGKD----AKEQGFVVVEKEELT--MIDNFF------------SEPTTKSWEIITVEEAKRR-----------------------------KSTCSYYEEEEEEEEGLPILQSHSALLENMHIEQLARRLPARVQGY-PWRLAYSTLEHGTSLKTLYRKSASLDS-----PVLLVIKDMDNQIFGAYATHPFRFSDH--YYGTGETFLYTFSPN-----------------------------FKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKK-EDFIVQDLESIITAQTDPGRLPVEDRHRRQKSEVQIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NI08-1", "uniprot_id": "NCOA7_HUMAN", "id": "Q8NI08-1", "name": "Nuclear receptor coactivator 7", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDTKEEKK---ERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLEPDKCNIAVEEEYMTDEKKKRKSNQLKEIRRTELKRYYSIDDNQNKTHDKKE-KKMVVQ--------------------------------KPHGTMEYTAGNQDTLNSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANSPSSTLRLSSSSPGATVSPSSSD-----------AEYDKLPDADLARKALKPIER----------VLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSDLPQDL----------------------------------------------------------------------CPLYRPGEWEDLASEKDINPFSKFKSINKEKRQQNGEKIMTSDSRPIVPLEKSTG--HTPTKPSGSSVSEKLKKLDSSRETSHGSPT-VTKLSKEPSDTSSAFESTAKENFLG-EDDDFVDLEELSSQTGGGMHKKDTLKECLSLDPEERKKAESQINNSAVEMQVQS-ALAFLGTENDVELKGALDLETCEKQDIMPEVDKQSGSPESRVENTLNIHEDLDKVKLIEYYLTKNKEGPQVSENLQKTELSDGKSIEPGGIDITLSSSLSQAGDPITEGNKEPDKTWVKKGEPLPVKLN--------------------------------------------SSTEANVI--KEALDSSLESTLDNSCQGAQMDNKSEVQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFATHTAAMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPD---VYGKD----AKEQGFVVVEKEELN--MIDNFF------------SEPTTKSWEIITVEEAKRR-----------------------------KSTCSYYEDEDE--EVLPVLRPHSALLENMHIEQLARRLPARVQGY-PWRLAYSTLEHGTSLKTLYRKSASLDS-----PVLLVIKDMDNQIFGAYATHPFKFSDH--YYGTGETFLYTFSPH-----------------------------FKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKK-EDFIVQDLEVWAFD-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4K620-1", "uniprot_id": "A0A0B4K620_DROME", "id": "A0A0B4K620-1", "name": "Oxidation resistance protein 1", "aln": "MSIIDSGKYRLRKDWASASIPSLVNIDEHDGDSGDTEGSLNATAPLPPQKPPRRSSLALGLFSSKSDKSQKRRSSIAVSFLRRDSSKNSTKDSYESAVRSEKSDGSGTPTSPEIVYSSEENIRASSPNDPGKQTFFEDGSQSPRPVLQGLNTSYEGPQNDRQRRRRSSLQTKLDRHRRKKMEYSNQRSLDSGMMCSESHSDLTNDSLAEGSGSFANRSRNGNDDEDDIIDPSHGEYFPREKRHSWWNIFVPDNFKNRSRRASQDVSSLSRSVDNLAIPVRRSKSRSVDHGLAAPFDLDSLRSKVEQRFESVDKLSRQKSSLPTIPTISYTVGNRDTLTSVAARFDTTPSELTHLNRLNSSFIYPGQQLLVPDKSAKDDASSSSTHDADGASLSGKSSPVERKLSGDESREKDILEGLRPGSPKPGHIERVGGSSQQQQAEEEANKSDDPVITQRFLKINVRHITDGQGVVGGVLLVTPNAVMFDPNVSDPLVIEHGPESYGVIAPMELVVNAAIFHDIAHMRVAGGAGQGLNSASGDAEKPEIYYPKPVLVEEDSKELPEQQSLLGEDGNKRLDAEIGSLEIADDQESLCSSTGRDGDAFPKAFDRERVEDSSMEAKDSAKTDALDDEDKKAGLGLSSTRSTLEERRKSLLDHHWAIPSKDRSSEDEGDNESNVTVDSGARVQDPHSANSSVSGVPLSQPPVAAAAAAAAVAPASAVVPLPPSGIDLEHLEQLSKQSCYDSGIDIREPVPNVQPIPKKTVYSDADIVLSSDWVPPKTIVPTHFSESPPRSTILGQSLDAGTGGAGGVRKKTSSVSFSVDDEAAQQAQAQSAALAVTDKQADKKNKMLKRLSYPLTWVEGLTGEGGAVPPGGVGSGSLNKSGDTDSAPNTGDSNQSVFSKVFSSSPITLVSELGGNLFSKTPSEDSGGSPVPPLTPHSTHSEGHMTYGRSSIGTFIRPHSSEGTSSSTKLKEAKQAPKLDYRSMVSMDDKPELFISVDKLIPRPARACLDPPLYLRLRMGKPIGKAIPLPTSVMS--YGKNKLRAEYWFSVPKNRVDELYRFINTWVKH---LYGELDEEQIKARGFELIQEDTEWTKSGTTKAGMGGGSQDGEEISDLTRESWELIKAPFAKTYKIIKTASHAASHDLEMLGGEVLSMSTDEYRKTSLFATGSFDLDFPIPDLIGKTEILTEEHREKLCSHLPARAEGY-SWSLIFSTSQHGFALNSLYRKMARLES-----PVLIVIEDTEHNVFGALTSCSLHVSDH--FYGTGESLLYKFNPS-----------------------------FKVFHWTGENMYFIKGNMESLSIGAGDGRFGLWLDGDLNQGRSQQCSTYGNEPLAPQ-EDFVIKTLECWAFV-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08952-1", "uniprot_id": "OXR1_YEAST", "id": "Q08952-1", "name": "Oxidation resistance protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFGVKDAIFKIKRSIAGTDSSDSTAYTTASESSPQLKDSHNPFRNKTTSERTIVEEG-----------------------------------------------------------------------------------------------------SLPPVRLNGYLPSTKN--KLLTPEMCDEIRTLMPTRIQLYTEWNLLYSLEQHGSSLHSLYSNVAPDSKEFRRVGYVLVIKDRKNGIFGAYSNEAFHPNEHRQYTGNGECFLWKLDKVPDVNISEKEESEQEGKEGKEEGDKEERWRFSGYPYTGVNEFAIYCTSEFLSMGAGDGHYGLLCDDGLLHGVSNPCQTYGNEVLSKEGKKFSIVALEVWRVG-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* :: :*.* : * * : ..* ::. ** . ::::.* . :**: . .:: .. : *.** ::: :. : ::* * : : . : :*.*.*.:.* * * * . * *:.* *: :.* : :* ", "identical_positions": 29, "similar_positions": 56, "identity": "2.06%" }, { "cls_id": "homologset.agr.SGD:S000006119", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LUE9-1", "uniprot_id": "F1LUE9_RAT", "id": "F1LUE9-1", "name": "Large ribosomal subunit protein uL30", "aln": "----------------------------------------------------LEGARGTLKK----------KKVPAVPETLKKKRRNFAELKVKRLRKKFALKTLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARKAGNFYVPAEPKLAF-------------VRNVLQLLRLRQIFNGTFVKLNKASVNMLRIVEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDISLIARSLG-KFGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRGGM--KKKTTHFVEGGDAGNREDQINRLIRRMN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0L1D0-1", "uniprot_id": "A0ABK0L1D0_RAT", "id": "A0ABK0L1D0-1", "name": "Large ribosomal subunit protein uL30", "aln": "MLTWEMHADWWAGTHNAAHYFRTCWATVLNVPWPSSLFPAGTMEAVPEKKKKVAAAPGTLKK----------KKVPAVPETLKKKRRNFAELKVKRLRKKFALKTLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASVNMLRIVEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDNSLVARSLG-KFGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRGGM--KKKTTHFVEGGDAGNREDQINRLIRRMN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14148-1", "uniprot_id": "RL7_MOUSE", "id": "P14148-1", "name": "Large ribosomal subunit protein uL30", "aln": "------------------------------------------MEAVPEKKKKVATVPGTLKKKVPAGPKTLKKKVPAVPETLKKKRRNFAELKVKRLRKKFALKTLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRIVEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDNSLIARSLG-KFGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRGGM--KKKTTHFVEGGDAGNREDQINRLIRRMN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18124-1", "uniprot_id": "RL7_HUMAN", "id": "P18124-1", "name": "Large ribosomal subunit protein uL30", "aln": "----------------------------------------------------MEGVE--EKK----------KEVPAVPETLKKKRRNFAELKIKRLRKKFAQKMLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRIVEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDNALIARSLG-KYGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRGGM--KKKTTHFVEGGDAGNREDQINRLIRRMN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32100-1", "uniprot_id": "RL7_DROME", "id": "P32100-1", "name": "Large ribosomal subunit protein uL30", "aln": "-----------------------------------------------------MPAPVVKKP--------AAKKLPAVPESKLKFSKKQISKRVAESKRRLKKAAVIALRKKENLVRAEKYQNEYIKAEQREIKLRRLAKKRNQFYVPAEAKLAFVVRIRGINKVAPKVRKVLQLFRLRQINNGVFIKLNKATINMLRIAEPYITWGYPNLKSVRELIYKRGFVKHNRQRVPITDNFVIERKLRQAHQIQCVEDLVHEIFTVGPNFKYASNFLWPFKLNTPTGGW--RKKANHYVNGGDFGNREDQINRLLRKMV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12213-1", "uniprot_id": "RL7B_YEAST", "id": "Q12213-1", "name": "Large ribosomal subunit protein uL30B", "aln": "-----------------------------------------------------MSTEKILTP-----------------ESQLKKTKAQQKTAEQIAAERAARKAANKEKRAIILERNAAYQKEYETAERNIIQAKRDAKAAGSYYVEAQHKLVFVVRIKGINKIPPKPRKVLQLLRLTRINSGTFVKVTKATLELLKLIEPYVAYGYPSYSTIRQLVYKRGFGKINKQRVPLSDNAIIEANLG-KYGILSIDDLIHEIITVGPHFKQANNFLWPFKLSNPSGGWGVPRKFKHFIQGGSFGNREEFINKLVKAMN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . *: * : . .: :: : *::** : *: * *: ..:** *: **.* *:****:** :* .*.*:*:.**::::*:: ***:::***. .::.:*:****: * *::*:.::* :: .* . * .::**:*** *** .** *.********..* ** :* .*:::**. ****: **:*:: * ", "identical_positions": 79, "similar_positions": 73, "identity": "25.08%" }, { "cls_id": "homologset.agr.SGD:S000006120", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F8VQG7-1", "uniprot_id": "F8VQG7_MOUSE", "id": "F8VQG7-1", "name": "NEDD4-binding protein 2-like 2", "aln": "--------------------------------------------------------------------------------------------------MDCLLELSATDAKGAESSAQTSGDRDSKPGAAGNSVMETCHPEGEGEDSKLDSFLDMQLTEDLDSLIQNAFEKLNSPPDDQVYPFSPLQDANSFNDPSTFMNSDSSGMTSLLSVQSTSSNSETLKSSASLPGSNPPTSHSVLNAPESCAK---LALEGGYSEGSPLSSSGNPTNGSVRGCGNFSQRQKDLSESECPSAQHSQALADLGNSDPQAPSTHPLHNSGSDLPGTDGDQKSASAPDVFVPSEGFNFKPHKHPELPPKGKDMNYCPVLTPLPLLLPPPPPPPIWNPMIPAFDLFQGNHGFVAPVVTTAAHWRPVNYTFPPPIISHNSPTKVWRGGEGASAYQVQEAPASQPVRKKATSFVGLVLVLLRGLPGSGKSFLARTLQEDNPGGVILSTDDYFYINGQYQFDVKYLGEAHEWNQNRAKEAFEKKVSPVIIDNTNLQAWEMKPYVALSQKHKYKVLFREPDTWWKFKPKELARRNIHGVSKEKISRMLEHYQRFVSVPIIMSSSDPEKTERIELCAYASDD---SPRDSEAISSAKEDSVSSASPKHSELTEEKTLEVATQAVLSVRDPQLPCPGLNRGRKELGDVSHGGHNPFFQEAPSTYFPNPESKGQATDRSEEEQ-EMVSEKEHCEADAWRPAGGASSDGRCADDNQEACGSAGAAALPGETPSPPEMLEERTAGKKKTIGKQKGKSSLEKIPKQELSNFVGDWPVDKTISQRTKRNRKTEKGLSVQSDKKGNLPQSHKVLDARVSVNTDPVQPQGSSHG---------NDDLSEVPSSYHYDPYRSTEQSSLSAVSDWPSSASLAPREHRPRMPKADLSEPSVEFGTNDNLGEIPLYPAHEAYWGTSPEELKTLSSS-LRSSEMLPSQTAPEHHPTSLNPLAHSQHA-LPLTFPSSAAALPGVVGPRSLTEFPVGVSGIVSGVDTGTCTQTEPQDFALLWKIEKNKINVSDSVRVLTGRLDGFKPKDFTLNRKVNVQETIPYRVMHDKSTFVEESELTSADESENLNILCKLFGSFSLEALKDLYERCNKDIIWATSLLLDSETKLCEDTAVESSPKSYSESQVGPFSMGLDLKEIISHRGTSEGSNSSVSEFSPGIGIRNTSARSAGNPGKGTSEQEGRRAMNPENPELITRVFPNAAVKVKSNNETLPDRQAELPGAYTFKQPLSLTPRSYIPKDVSEIEKNLVMTETRDNMHSFLNLSDIINSATSTSNPELNEDVYLTGSLEVKKNENLPKDYVKFANMEEFINEDKQEMEKNLMPGSGWSAGVSEEGKAEVLTPTPVTATSLTIDCLELALPPELAFQLNELFGPVGIDSGSLTVEDCVVHIDLNLAKVIHEKWRESVMERQRQEEVSRGKRTQDPLLAGHTGLDNFEQKSSQKTGKRLLKTLAAPETL---DHWNTQTKKVSLREIMSEEIALQEKHDLKRETLMFEKDCATKLKEKQLFKIFPAINQNFLVDIFKDHSYSLENTVQFLNCVLEGDPVKTVVAQECVHQNENNT-YTAQKSKEKKAKKPKEAEDSPGDPSFQDFEYPEYDDYRAEAFLHQQKRMECYSKAKEAYRMGKKNVATFYAQQGSLHEQKMKEANHLAAVEIFEKVNASLLPQNVLDLHGLHVDEAIEHLTAVLQQKTEEFKQSGGKPYLSVITGRGNHSQGGVARIKPAVIKYLTSHSFRFSEIKPGCLKVMLK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A4H4-1", "uniprot_id": "A0A8I6A4H4_RAT", "id": "A0A8I6A4H4-1", "name": "NEDD4-binding protein 2-like 2", "aln": "MSIVSASQPGNILVLEVRMPRKRKNVGGNPLRKTANSKKSVVSRVASREEPTTTLPSMCETKIDQEELFTSISEMFSALDPDVVYLMLSECDFKVESAMDCLLELSAANAKMEASPSQTSAARERRLRASGGTVTGTRRPEDETEDSKLDSFLDMQLTEDLDSLIQNAFEKLNSPPDDQVYPFSPLQDANSFNDPSTFVNSDSSGMTSLPSVQNTGSNSEIVKSSAALLGSNPLTSHSVLNEPESCAQSSTLALEEGYLEDSPLGSSSNPANDSVMGCGNFSQRQKDHLESECPSVQHSQALVSVGNSEPQVPSNRSLHNSGSDLPSTDGDQKSTSAPDVFVPSEGFSFKPHKHPELPPKGKDMNYCPVLTPLPLLLPPPPPPPIWNPMIPAFDLFQGNHGFVAPVVTTAAHWRPVNYTFPPPIISHTSPTKVWRGSEGASAYQVQEAPVSQPARKKTTSYVGLVLVLLRGLPGSGKSFLARTLQEDNPGGVILSTDDYFYINGQYQFDVKYLGEAHEWNQNRAKEAFEKKVSPVIIDNTNLQAWEMKPYVALSQKHKYKVLFREPDTWWKFKPKELARRNIHGVSKEKISRMLEHYQRFVSVPIIMSSSDPEKTERIELCAYACEDRNSSPRDSEAVTSTKEENVSSASPKHLDLTEEKTLEVATQAVLPSSEPPLPPTSLNRGRKELGDGSHSVHGHFIQEDPSTYFPNAEGSVQAPDRSEKEQ-EVVSAKERSEADAWSPAEGASSNGHCVEGDQEASEFASAATLPRENPSPPEILEERTAGKKKTIGKQKSKSSLEK-PKPELSNFVGDWPVDKTISQRTKRNRKTEKGSSVQNDKKCNRPQSHKVLDTRVSVNTDPIQPQGSPHG---------NDDPSEVPSNYHYDPYKSTEQTSFSTVSDWPSSASLAQREHRSRMPKAGLSEPNVEFGTNDKLGEIPLYPAHEAYWGTSPEELKTLSSN-LRSSEVLPSKTAHEHHQTPLSQMVPGQHT-LPLPFPSSAATLPGVVGPRALTEFPVGVSGIVSGVDTGTCTQTEPQDFALLWKIEKNKISVSDSVRVLTGRVDGFKPKDFTLNRKLNVQETIPYRVMHDKSTFVEESELTNADESENLNILCKLFGSFSLEALKDLYERCNKDIIWATSLLLDSETKLCEDAEVVNPPESYSESQVGPFSMGLDLKEIISHRGTSEGSNSCVSEFSPGIGIRNTSAQSDGDPEKGNSEQEGIRAINPENPESVARIFPNATVNVKSSNGMAPD----LSGAYTFKQPLSLTPRSYVPKDVSEIEKSLVT-ETRDNIHSFLNLSDIINSATSTSNPELNEDVYLTGSLEVKKNENLPKDYVKFANMEEFINEDKQEMEKSLMPGTGWSAGVSEESKPEVSTPAPVAAKSLTIDCLELTLPPELAFQLNELFGPVGVDSGSLTVEDCVVHIDLNLAKVIHEKWRESVMERQRQEEVSLGKRMQDPSLAGHTVLDNSEQKSSQKTGKRLLKTLAAPETL---DHWNTQTKKVSLREIMSEEIALQEKHDLKRETLMFEKDCATKLKEKQLFKIFPAINQNFLADIFKDHNYSLENTVQFLNCVLEGDPVKTVIAQECAHQNESNTSHSAQKSKEKKAKKPKEADDTAGDPSFQDFEYPEYDDYRAEAFLHQQKRMECYSKAKEAYRMGKKNVATFYAQQGSLHEQKMREANHLAAVEIFEKVNASLLPQNVLDLHGLHVDEAIEHLTAVLQQKTEEFKQSGGKPYLSVITGRGNHSQGGVARIKPAVIKYLTSHSFRFSEIKPGCLKVMLK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86UW6-1", "uniprot_id": "N4BP2_HUMAN", "id": "Q86UW6-1", "name": "NEDD4-binding protein 2", "aln": "------------------MPRRRKNLGGNPFRKTANPKEVVVSSVASREEPTTTLPSMGETKVDQEELFTSISEIFSDLDPDVVYLMLSECDFKVENAMDCLLELSATDTKIEESSSQSFVASENQVGAAESKIMEK-RPEEESEDSKMDSFLDMQLTEDLDSLIQNAFEKLNSSPDDQVYSFLPSQDVNSFNDSSEFINPDSSNMTPIFSTQNMNLNGENLENSGSTLSLNPLPSHSVLNESKCFIKDNTLALESNYPEDSLLSSSLNVASDSIAGCSSLNQKQKELLESECVEAQFSEAPVDLDASEPQA----CLNLPGLDLPGTGGDQKSTRVSDVFLPSEGFNFKPHKHPELPTKGKDVSYCPVLAPLPLLLPPPPPPPMWNPMIPAFDLFQGNHGFVAPVVTTAAHWRSVNYTFPPSVISHTSPTKVWRNKDGTSAYQVQETPVSQVVRKK-TSYVGLVLVLLRGLPGSGKSFLARTLQEDNPSGVILSTDDYFYINGQYQFDVKYLGEAHEWNQNRAKEAFEKKISPIIIDNTNLQAWEMKPYVALSQKHKYKVLFREPDTWWKFKPKELARRNIHGVSKEKITRMLEHYQRFVSVPIIMSSSVPEKIERIELCAYSCEDRSTSPRDDEDIISEKEENILSLSLKHLEFTEEKNLDVTKETMLPENVAYLSNADLNKRRKEISDMNPSIQSALILETPHMYFSDSESKLQATDKSENEQIEMVAVKGYSKTDTDSSMERVSPSTCCSENNQEDCDLANSGPLQNEKSSPGEIVEERATVTKKAFGKQKSKSTLEKFPRHELSNFVGDWPVDKTIGQRTKRNRKTEKTSSVQSDKKYNYPQSHKLVNS-VSVNTDCVQQRGSPHESVEDGRKSQCDDASEPLNSYKYDAYKNIDKNSFNIMGDWPSSDSLAQREHRSRMPKTGLSEPNLEIGTNDKMNEISLSTAHEACWGTSSQKLKTLGSSNLGSSEMLLSEMTCES-QTCLSKKSHGQHTSLPLTFTNSAPTVSGVVEPQTLAECQEQMPKRDPGKEVGMCTQTEPQDFALLWKIEKNKISISDSIKVLTGRLDGFKPKVFNINTKSDVQEAIPYRVMYDKSTFVEESELTSADESENLNILCKLFGSFSLEALKDLYERCNKDIIWATSLLLDSETKLCEDTEFENFQKSCDGSQIGPFSLGLNLKEIISQRGTLENSNSPVPEFSHGIGISNADSQSTCDAERGNSEQAEMRAVTPENHESMTSIFPSAAVGLKNNNDILPNSQ--EELLYSSKQSFPGILKATTPKDMSETEKNLVVTETGDNIHSPSHFSDIFNFVSSTSNLELNEEIYFTDSLEIKRNENFPKDYVKFSDEEEFMNEDEKEMKEILMAGSSLSAGVSGEDKTEILNPTPAMAKSLTIDCLELALPPELAFQLNELFGPVGIDSGSLTVEDCVVHIDLNLAKVIHEKWKESVMERQRQEEVSCGKFMQDPSLVGHTGLDNPEQKSSQRTGKKLLKTLTASEMLPLLDHWNTQTKKVSLREIMSEEIALQEKHNLKRETLMFEKDCATKLKEKQLFKIFPAINQNFLVDIFKDHNYSLEHTVQFLNCVLEGDPVKTVVAQEFVHQNENVTSHTGQKSKEKKPKKLKETEETPSELSFQDFEYPDYDDYRAEAFLHQQKRMECYSKAKEAYRIGKKNVATFYAQQGTLHEQKMKEANHLAAIEIFEKVNASLLPQNVLDLHGLHVDEALEHLMRVLEKKTEEFKQNGGKPYLSVITGRGNHSQGGVARIKPAVIKYLISHSFRFSEIKPGCLKVMLK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08954-1", "uniprot_id": "NBR9_YEAST", "id": "Q08954-1", "name": "Endonuclease NBR9", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKGTGGVVVG--------------------TQNPVRDYNHSTDEEYQRLRRLADEAYKKRDQLSHESQTAYQQGDKKLAHELSE---------------------KSKAQLKTAEDFNMQAAEYVFVENNADSSSNE--IDLHGLYVKEALFILQKRIKFAIDHNEPQLNVIVGKG-------------------------------------------------------------LHSQN----------GIAKLKPSIEEFCAKHG--------------IRNHLEKGNSGVL---VLELQGVQMQMDGP----AVNAPTNQYNAQPHPQYN----NNGGQPQGQAQNYNNSGNDNKDSTLTSIFKIFCNCIQSLA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. *: * : ::. :** . : * : *.: .*.: *: .*:* : *: . :: *..::: :* :: * . .:: :.:. :: * : * .:::::. ** :: . **.*: . * .: * *::* : :** *:.:* **:*:*:::: .:: *:::: . * ..*.:.** . . : : . * : :* .*:: : ", "identical_positions": 42, "similar_positions": 95, "identity": "2.34%" }, { "cls_id": "homologset.agr.SGD:S000006124", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51817-1", "uniprot_id": "PRKX_HUMAN", "id": "P51817-1", "name": "cAMP-dependent protein kinase catalytic subunit PRKX", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MEAPGLAQAAAAESDSRK-----VAEETP--------------------------------------------------DGAPALCPSPEALSPEP-------------------------PVYSLQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDN--PFGIYQKILAGKIDFPRHLDFHVKDLIKKLLVVDRTRRLGNMKNGANDVKHHRWFRSVDWEAVPQRKLKPPIVPKIAG-DGDTSNFETYPENDWDTAAPVPQKDLEIFKNF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P16912-1", "uniprot_id": "KAPC3_DROME", "id": "P16912-1", "name": "cAMP-dependent protein kinase catalytic subunit 3", "aln": "MDLWHIFLERILVACRVSASVFANFGCGLYSSWKLICGDHDSASGLRAGLATPTQRGKATGDNGTTGTPARTIGKPQARIATAMSTATCARFCTPLSSGTAGSTSKLTTGNGSGNTMTSAYKIPSNNSTTANDSSNTETTFTFKLGRSNGRSSSNVASSESSDPLESDYSEEDPEQEQQRPDPATNSRSSSTATTTTTSSADHDNDVDEEDEEDDENEGEGNGRDADDATHDSSESIEEDDGNETDDEEDDDESEESSSVQTAKGVRKYHLDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQ--PFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHH-DGDTKNFDDYPEKDWKPAKAVDQRDLQYFNDF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06245-1", "uniprot_id": "KAPB_YEAST", "id": "P06245-1", "name": "cAMP-dependent protein kinase type 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------MEFVAERAQPVGQTIQQQNVNTYGQGVLQPHHDLQQ-----------------------------------------------RQQQQQQRQHQQLLTSQLPQ-----------------KSLVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTT--PMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFDQYPEEQLDYGIQGDDPYAEYFQDF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P68182-1", "uniprot_id": "KAPCB_RAT", "id": "P68182-1", "name": "cAMP-dependent protein kinase catalytic subunit beta", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MGN--TAIAKKGSEVESVK------------------------------------------------------------EFLAKAKEDFLRKWENPPPS------------------------NAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQ--PIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRG-SGDTSNFDDYEEEEIR--VSITEKCGKEFCEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P68181-1", "uniprot_id": "KAPCB_MOUSE", "id": "P68181-1", "name": "cAMP-dependent protein kinase catalytic subunit beta", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MGN--TAIAKKGSEVESVK------------------------------------------------------------EFLAKAKEDFLRKWENPPPS------------------------NAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQ--PIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRG-SGDTSNFDDYEEEEIR--VSITEKCGKEFCEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22694-1", "uniprot_id": "KAPCB_HUMAN", "id": "P22694-1", "name": "cAMP-dependent protein kinase catalytic subunit beta", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MGN--AATAKKGSEVESVK------------------------------------------------------------EFLAKAKEDFLKKWENPTQN------------------------NAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQ--PIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRG-SGDTSNFDDYEEEDIR--VSITEKCAKEFGEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05132-1", "uniprot_id": "KAPCA_MOUSE", "id": "P05132-1", "name": "cAMP-dependent protein kinase catalytic subunit alpha", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MGN--AAAAKKGSEQESVK------------------------------------------------------------EFLAKAKEDFLKKWETPSQN------------------------TAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQ--PIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKG-PGDTSNFDDYEEEEIR--VSINEKCGKEFTEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27791-1", "uniprot_id": "KAPCA_RAT", "id": "P27791-1", "name": "cAMP-dependent protein kinase catalytic subunit alpha", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MGN--AAAAKKGSEQESVK------------------------------------------------------------EFLAKAKEDFLKKWEDPSQN------------------------TAQLDHFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQ--PIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKG-PGDTSNFDDYEEEEIR--VSINEKCGKEFTEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P17612-1", "uniprot_id": "KAPCA_HUMAN", "id": "P17612-1", "name": "cAMP-dependent protein kinase catalytic subunit alpha", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MGN--AAAAKKGSEQESVK------------------------------------------------------------EFLAKAKEDFLKKWESPAQN------------------------TAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQ--PIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKG-PGDTSNFDDYEEEEIR--VSINEKCGKEFSEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22612-1", "uniprot_id": "KAPCG_HUMAN", "id": "P22612-1", "name": "cAMP-dependent protein kinase catalytic subunit gamma", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MGN--APAKKDTEQEESVN------------------------------------------------------------EFLAKARGDFLYRWGNPAQN------------------------TASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQ--PIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPKYTG-PGDASNFDDYEEEELR--ISINEKCAKEFSEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12370-1", "uniprot_id": "KAPC1_DROME", "id": "P12370-1", "name": "cAMP-dependent protein kinase catalytic subunit 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MGNNATTSNKKVDAAETVK------------------------------------------------------------EFLEQAKEEFEDKWRRNPTN------------------------TAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQ--PIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKG-PGDTSNFDDYEEEALR--ISSTEKCAKEFAEF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P16911-1", "uniprot_id": "KAPC2_DROME", "id": "P16911-1", "name": "cAMP-dependent protein kinase catalytic subunit 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MSQHT--SQYVFNSKEDYN------------------------------------------------------------VILDNMSREFEERWNHQTQS-----------------------PYTNLENYITRAVLGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKRVDGRTSTLCGTPEYLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSKICICDYKMPSYFTSQLRSLVESLMQVDTSKRLGNSNDGSSDVKSHPWFQGVDWFGILNQEVTAPYQPTISG-AEDLSNFENFEFKDRY--KSRINRHPELFANF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VA47-1", "uniprot_id": "Q9VA47_DROME", "id": "Q9VA47-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MGPQPEQAQMHFSPKVDYI------------------------------------------------------------LILDKLREDFNKKFATNTPS-----------------------PSTGLDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKVETRTMTLCGTPEYLPPEIIQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEADYKMPSYFSGALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAPYVPNISN-PEDISNFDKVSDKPRP--KAKTMRHEEAFADF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: .:* *:** * : : . * * : .::: ** * .*: :*. .* : : : ::::: : ***:*: :. :* . . **:*:: :.:*:* :::*******:::: *::::*****:*.: * ******:*:.**:: : :. :****::*:*::*: * .** : *.** : *: *: * ::* ** * *:* : ** * : : : .* * * . *: : : * :*", "identical_positions": 78, "similar_positions": 90, "identity": "13.31%" }, { "cls_id": "homologset.agr.SGD:S000006125", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JMK2-1", "uniprot_id": "KC1E_MOUSE", "id": "Q9JMK2-1", "name": "Casein kinase I isoform epsilon", "aln": "--------MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFG----------------------AARNPEDVDRERREH----------------------------EREERMGQLRGSATRALPPGPPTG--------ATANRLRSAAEPVASTPASRIQQTGNTS-PRAISRADRERKVSMRLHRGAPANVSSS---DLTGRQEVSRLAASQTS-------VPFDHLGK---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49674-1", "uniprot_id": "KC1E_HUMAN", "id": "P49674-1", "name": "Casein kinase I isoform epsilon", "aln": "--------MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFG----------------------AARNPEDVDRERREH----------------------------EREERMGQLRGSATRALPPGPPTG--------ATANRLRSAAEPVASTPASRIQPAGNTS-PRAISRVDRERKVSMRLHRGAPANVSSS---DLTGRQEVSRIPASQTS-------VPFDHLGK---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DC28-1", "uniprot_id": "KC1D_MOUSE", "id": "Q9DC28-1", "name": "Casein kinase I isoform delta", "aln": "--------MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFG----------------------ASRAADDAERERR------------------------------DREERLRHSRNPATRGLPS-------------TASGRLRGTQEVAPPTPLTPTSHTANTS-PRPVSGMERERKVSMRLHRGAPVNVSSS---DLTGRQDTSRMSTSQIP-------GRVASSGLQSVVHR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06486-1", "uniprot_id": "KC1D_RAT", "id": "Q06486-1", "name": "Casein kinase I isoform delta", "aln": "--------MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFG----------------------ASRAADDAERERR------------------------------DREERLRHSRNPATRGLPS-------------TASGRLRGTQEVAPPTPLTPTSHTANTS-PRPVSGMERERKVSMRLHRGAPVNVSSS---DLTGRQDTSRMSTSQIP-------GRVASSGLQSVVHR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48730-1", "uniprot_id": "KC1D_HUMAN", "id": "P48730-1", "name": "Casein kinase I isoform delta", "aln": "--------MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFG----------------------ASRAADDAERERR------------------------------DREERLRHSRNPATRGLPS-------------TASGRLRGTQEVAPPTPLTPTSHTANTS-PRPVSGMERERKVSMRLHRGAPVNISSS---DLTGRQDTSRMSTSQIP-------GRVASSGLQSVVHR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P3K7-1", "uniprot_id": "KC1DB_DANRE", "id": "Q6P3K7-1", "name": "Casein kinase I isoform delta-B", "aln": "--------MELRVGNRYRLGRKIGSGSFGDIYLGTDISVGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFG----------------------ANRTAEEADRERR------------------------------ERDERMRHSRNPAARGIP--------------AASGRPRPTQDGAPPTPLTPTSHTANTSSPRPVTGMERERKVSMRLHRGAPVNVSSS---DLTGRQDTSRMSTSQNS-------IPFDHHGK---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7T2E3-1", "uniprot_id": "KC1DA_DANRE", "id": "Q7T2E3-1", "name": "Casein kinase I isoform delta-A", "aln": "--------MELRVGNRYRLGRKIGSGSFGDIYLGTDITTGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFG----------------------GAR--EDPERDRR------------------------------DREERIRQGRIPLPRVMLP-------------TSSGRPRGTQEVAPAPPLTPDSHT----------GMERERKVSMRLHRGAPVNVSSS---DLTGRQDCSRISTSQAH-------SRVP-SGLQSAVPR---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O76324-1", "uniprot_id": "DCO_DROME", "id": "O76324-1", "name": "Discs overgrown protein kinase", "aln": "--------MELRVGNKYRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQGGIGIPRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMISRIDYIHSRDFIHRDIKPDNFLMGLGKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKLSTSIVVLCKGFPSEFVNYLNFCRQMHFDQRPDYCHLRKLFRNLFHRLGFTYDYVFDWNLLKFG----------------------GPRNPQAIQQAQDGA----------------------------DGQAGHDAVAAAAAVAAAAAASSHQQQ---QHKVNAALGGGGGSAAQQQLQGGQTLAMLGGNGGGNGSQLIGGNGLNMDDSMAATNSSRPPYDTPERRPSIRMRQGGGGGGGGVGVGGMPSGGGGGGVGNAK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8BK63-1", "uniprot_id": "KC1A_MOUSE", "id": "Q8BK63-1", "name": "Casein kinase I isoform alpha", "aln": "MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQK----------------------AAQQAASSSGQGQ---------------------------------------------------------------QAQTPTGKQTDKTKSNMKGF--------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48729-1", "uniprot_id": "KC1A_HUMAN", "id": "P48729-1", "name": "Casein kinase I isoform alpha", "aln": "MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQK----------------------AAQQAASSSGQGQ---------------------------------------------------------------QAQTPTGKQTDKTKSNMKGF--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97633-1", "uniprot_id": "KC1A_RAT", "id": "P97633-1", "name": "Casein kinase I isoform alpha", "aln": "MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQGKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQK----------------------AAQQAASSSGQGQ---------------------------------------------------------------QAQTPT------------GF--------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N752-1", "uniprot_id": "KC1AL_HUMAN", "id": "Q8N752-1", "name": "Casein kinase I isoform alpha-like", "aln": "MTNNSGSKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEDVAVKLESQKVKHPQLLYESKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLRAMTKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQK----------------------AAQQAASSSGQGQ---------------------------------------------------------------QAQTQTGKQTEKNKNNVKDN--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29295-1", "uniprot_id": "HRR25_YEAST", "id": "P29295-1", "name": "Casein kinase I homolog HRR25", "aln": "--------MDLRVGRKFRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYLSGGVGIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYCHRRFSFKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMGVGRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQSRRDDLESLGYVLIYFCKGSLPWQGLKATTKKQKYDRIMEKKLNVSVETLCSGLPLEFQEYMAYCKNLKFDEKPDYLFLARLFKDLSIKLEYHNDHLFDWTMLRYTKAMVEKQRDLLIEKGDLNANSNAASASNSTDNKSETFNKIKLLAMKKFPTHFHYYKNEDKHNPSPEEIKQQTILNNNAASSLPEELLNALDKGMENLRQQQPQQQVQSSQPQPQPQQLQQQPNGQRPNYYPEPLLQQQQRDSQEQQQQVPMATTRATQYPPQINSNNFNTNQASVPPQMRSNPQQPPQDKPAGQSIWL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ** :::: **********:* . **:**:***. : :**** **:.* :.**:*** : * * : *.:*::***********:* *:*::***::** **:.**:*:* :.*:***:******** *:: . :.:*****:**:** .: :******:* * **.****:*:***********:******::** :******:* .*:***::* ***:...: .**.* * ** *: :*: ::*:: *** .* :**: * . *: ***.:*: . . ", "identical_positions": 153, "similar_positions": 86, "identity": "30.48%" }, { "cls_id": "homologset.agr.SGD:S000006127", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q0VGK4-1", "uniprot_id": "GDPD1_RAT", "id": "Q0VGK4-1", "name": "Lysophospholipase D GDPD1", "aln": "MSSTAAFCLLSTLGG---YLVTSFLLLKYPALLHQRKKQRFLSRHISHRGGAGENLENTMAAFQHAVTIGTDMLELDCHITKDEQVVVSHDANLKRSTGVNVNVSDLKYCELPPYLCKLDVPFQRACKCEGTDTRIPLLKEVFEAFPETPINIDIKVNNNVLIQKVSELVKQYKREHLTVWGNASSEIVDKCYKENSDIPILFSLQRVLLILGLFFTGLLPFVPIREQF-FEIPMPSIILKLKEPHIISKGHKFLIWLSDTLLMRKALFDHLT-ARGIQVYIWVLNEEHEYKRAFDLGATGVMTDYPTKLKEFLNNMS-------A----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CRY7-1", "uniprot_id": "GDPD1_MOUSE", "id": "Q9CRY7-1", "name": "Lysophospholipase D GDPD1", "aln": "MSSTAAFCLLSTLGG---YLVTSFLLLKYPALLHQRKKQRFLSRHISHRGGAGENLENTMAAFQHAVTIGTDMLELDCHITKDEQVVVSHDANLKRSTGVNVNVSDLKYCELPPYLCKLDVPFQRACKCEGKDTRIPLLKEVFEAFPETPINIDIKVNNNVLIKKVSELVKQYKREHLTVWGNANSEIVDKCYKENSDIPILFSLQRVLLILGLFFTGLLPFVPIREQF-FEIPMPSIILKLKEPHTISKGHKFLIWLSDTLLMRKALFDHLT-ARGIQVYVWVLNEEYEYKRAFDLGATGVMTDYPTKLKDFLNNFS-------A----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N9F7-1", "uniprot_id": "GDPD1_HUMAN", "id": "Q8N9F7-1", "name": "Lysophospholipase D GDPD1", "aln": "MSSTAAFYLLSTLGG---YLVTSFLLLKYPTLLHQRKKQRFLSKHISHRGGAGENLENTMAAFQHAVKIGTDMLELDCHITKDEQVVVSHDENLKRATGVNVNISDLKYCELPPYLGKLDVSFQRACQCEGKDNRIPLLKEVFEAFPNTPINIDIKVNNNVLIKKVSELVKRYNREHLTVWGNANYEIVEKCYKENSDIPILFSLQRVLLILGLFFTGLLPFVPIREQF-FEIPMPSIILKLKEPHTMSRSQKFLIWLSDLLLMRKALFDHLT-ARGIQVYIWVLNEEQEYKRAFDLGATGVMTDYPTKLRDFLHNFS-------A----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z9C9-1", "uniprot_id": "A0A8M6Z9C9_DANRE", "id": "A0A8M6Z9C9-1", "name": "", "aln": "-MDTVSWVLLLCLAVL-FYVVCSLFLLRYPLILHKRKRLEFYCRHISHRGGSGERIENTMEAFTHAVSAGTDMLEMDCHLTLDGYVVVSHDNNLLRQTGDDKTVSSLKFQDLPLYEEKLEVTFYVGHYSTGKDRRFVLLENVLKNFPNMPMTLEIKENNDLLIKKVSNLVHKYGREHITVWASEEHEVMAKCLKQNPSMPYMFTMRRVIMLLLLFYTGLLPFVPLGESV-LMFYLPRIINRTYIPEEAYMKNRFVVYLLQKLITWKSLFEHLI-KRGLQVQLFVCNEETDMAAAFAMGATGVMTDYPTVLSDYIRKHP-------PPPAVY-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q99LY2-1", "uniprot_id": "GDPD3_MOUSE", "id": "Q99LY2-1", "name": "Lysophospholipase D GDPD3", "aln": "-MIPLLYFVLPTLGS---YVMLSIFFLRRPHLLHTPRAPVFPIRLAAHRGGSGERLENTMEAVENSMAQRADLLEFDCQLTRDGVVVVSHDKNLSRQSGLNKDVNTLDFEELPLYKEELEIYFSPGHFAHGSDRHMISLEDVFQKFPRTPMCLEVKERNEELIHKVANLTRRFDRNEITIWAAEKSSVMKRCRAANPEMPMAFTIWRSFWILLLYYLGLLPFVSIPEKF-FFCFLPTIINRTYFPFRCGWMNQLSATITKWIIMRKSLIRHLQ-DRGVQVLFWCLNEESDFEVAFSLGANGVMTDYPTALRHYLDKQEEETQPPQPEALSCLSLKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A1N8-1", "uniprot_id": "D4A1N8_RAT", "id": "D4A1N8-1", "name": "Lysophospholipase D GDPD3", "aln": "-MIPLVYFVLPTLGS---YVILSIFFLRRPHLLHTPWAPGFSIRLAAHRGGSGERLENTMEAIENSMAQRADLLEFDCQLTRDGVVVVSHDKNLSRQSGLNKDINTLDFAQLPLYKEELEIYFSPGHFAHGSDRHMISLEDVFQKFPRTPMCLEIKEKNEELIHKVANMARRFNRNEITIWTSEKNSIMKRCKAANPEMPTAFTIWRSFWILLLYYLGLLPFVSIPEKF-FFCFLPTIINRTYFPFSCGWMNKLSATVTKWAIMRKSLIQYLQ-DRGVQVLFWCLNEESDFEVAFSLGANGVMTDYPTALRHYLDKQE------QRDSASSV----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7L5L3-2", "uniprot_id": "GDPD3_HUMAN", "id": "Q7L5L3-2", "name": "Lysophospholipase D GDPD3", "aln": "-MSLLLYYALPALGS---YAMLSIFFLRRPHLLHTPRAPTFRIRLGAHRGGSGELLENTMEAMENSMAQRSDLLELDCQLTRDRVVVVSHDENLCRQSGLNRDVGSLDFEDLPLYKEKLEVYFSPGHFAHGSDRRMVRLEDLFQRFPRTPMSVEIKGKNEELIREIAGLVRRYDRNEITIWASEKSSVMKKCKAANPEMPLSFTISRGFWVLLSYYLGLLPFIPIPEKF-FFCFLPNIINRTYFPFSCSCLNQLLAVVSKWLIMRKSLIRHLE-ERGVQVVFWCLNEESDFEAAFSVGATGVITDYPTALRHYLDNHG-------PAARTS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08959-1", "uniprot_id": "PGC1_YEAST", "id": "Q08959-1", "name": "Phosphatidylglycerol phospholipase C", "aln": "MVEIVGHRAFKARYPENTLLAFEKAYAAGADVIETDLQMTSDGMVVVNHDSDTGRMWDKNLVIGESTWEEVKRLRCKEDGSLAMMTLKEILTWAVCHPGAKLMLDIKFTNEKIIMIKTFVIMLEVKNDLKFWQERITWGLWLLDWYDFGIETGVLKDFKVIVISLSLDIASQFVKRSLTLN-DPHYKLFGISVHFVSSWTSQFRLRLLPVLMKNDIKVYLWTVNKPIDFKYLCELPIHGAITDDPIKARKLCDGHTVAKKPTAEKKFVAPSLASVDGLRFHAFIKVYNILCTLLYSKWVHIKLCGWSIAYVIFLFLRT----------IHFL----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . ::. ::.. : :. .. .: . *. . . : .: . .* . :. : : : : : :: ::. : :* : :* :. :: :. :*: .:. . .. . * : :: * : .. :* * . * : * *::. : : : . : .:. :: ", "identical_positions": 12, "similar_positions": 80, "identity": "3.57%" }, { "cls_id": "homologset.agr.SGD:S000006128", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABZ3NNP0-1", "uniprot_id": "A0ABZ3NNP0_RAT", "id": "A0ABZ3NNP0-1", "name": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1", "aln": "MELPTDPPLYTLNQSEKYRKCSNIFPRVTIDGFSLVPPLFYLSLSERRLELPLAPSSSSSGPASVPCSQCGRACGRHGFPSPVNPTFLISVPGSLCLLAICGARAPWRMGPPLDVWDFSS-PLLSLWMNRFYIYMGCALGVTLWFCVQIIIKKQVTRSQEKSVPGAP-----DSSLSPQEKHTHVSGVKI---FYGSQTGTAKGFAVVLAKA-------VTSLDLPVAIINLKEYDPDDNLIGEITSKNVCAFLVATYTDGRPTESAEWFCK---WLEEAANDFRFGKTYLKGLRYAVFGLGDSAYRSHFNKVSTNVDKWLWMLGAQRVLTRGEGDCNAVQSKHGSIEA-------DFTAWKTKFISR-----------------------LQALQRGE-KKGCG--------GDCKRGKCESAQHGP--GEVRSHPHGELHPGDAEEEEPCESSSEDEHGT---KGYQSLNSVVDVEDLGNIMNPVKREKREKAQPEEKVV-----VHRNSEKNE------DSEARAMITP--ALREALTKQGYQLIGSHSGVKLCRWTKSMLRGRGGCYKHTFYGIESHRCMEATPSLACANKCVFCWRHHTNPVGTEWRWKMDQPELILKEAIENHRNMIKQFKGVPGLKAERFEEGMEVKHCALSLVGEPIMYPEINRLLKLLHQHGISTFLVTNAQFPEEIRNLTPVTQLYVSVDASTKDSLKKIDRPLFKDFWQRFLDSLQALSAKQ--QRTVYRLTLVKCWNVDELQAYAELVSLGSPDFIEVKGVTYCGES--AASSLTMANVPWHEEVVRFVRELVDLLP----DYEIACEHEHSNCLLIGHKKFKIGGEWWTWIDYSRFQELVLQYEESGGSKTFSSKDYMARTPQWALFGARERGFDPKDTRYQRKNKTKDISGC---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJM7-1", "uniprot_id": "TYW1_MOUSE", "id": "Q8BJM7-1", "name": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1", "aln": "------------------------------------------------------------------------------------------------------------MG-PLDVWDLS--PLLSLWMNRFYIYMGCALGLTLCICVQ-IIKKQVTRSQEKRVPGAP-----DSSLSPQKKQTHVSGVKI---FYGSQTGTAKGFAVVLAKA-------VTSLDLPVAIINLKEYDPDDSLIGEITSKTVCAFLVATYTDGCPTESAEWFCK---WLEESANDFRFGKTYLKGLRYAVFGLGDSAYRSHFNKVSTNVDKWLWMLGAQRVLTRGEGDCNAVQSKHGSIEA-------DFTAWKTKFISR-----------------------LQALQRGE-KKACG--------GNCKRGKCESAQHGP--GEARPHPQGELHPGDAEEEEPCESSSEDELGT---QDYQSLTSVVDVEDLGNIMNPVKREKREKSHQDGKAA-----MQRNPEKTE------DGEGRAMITP--ALREALTKQGYQLIGSHSGVKLCRWTKSMLRGRGGCYKHTFYGIESHRCMEATPSLACANKCVFCWRHHTNPVGTEWRWKMDQPELILKEAIENHQNMIKQFKGVPGLKAERFEEGMEVKHCALSLVGEPIMYPEINRLLKLLHQHGISSFLVTNAQFPEEIRKLTPVTQLYVSVDASTRDGLKKIDRPLFKDFWQRFLDSLKALSAKQ--QRTVYRLTLVKCWNVDELQAYAELVSLGNPDFIEVKGVTYCGES--AASSLTMANVPWHEEVVRFVRELVDLLP----DYEVACEHEHSNCLLIGHKKFKIDGEWWTWINYSRFQELVLQYEESGGSKTFSSRDYMARTPQWALFGARERGFDPKDTRYQRKNKTKDISGC---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NV66-1", "uniprot_id": "TYW1_HUMAN", "id": "Q9NV66-1", "name": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1", "aln": "------------------------------------------------------------------------------------------------------------MDPSADTWDLFS-PLISLWINRFYIYLGFAVSISLWICVQIVIKTQGKNLQEKSVPKAAQDLMTNGYVSLQEKDIFVSGVKI---FYGSQTGTAKGFATVLAEA-------VTSLDLPVAIINLKEYDPDDHLIEEVTSKNVCVFLVATYTDGLPTESAEWFCK---WLEEASIDFRFGKTYLKGMRYAVFGLGNSAYASHFNKVGKNVDKWLWMLGAHRVMSRGEGDCDVVKSKHGSIEA-------DFRAWKTKFISQ-----------------------LQALQKGERKKSCG--------GHCKKGKCESHQHGSEEREEGSHEQDELHHRDTEEEEPFESSSEEEFGG---EDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSG-----LFRNMGRNE------DGERRAMITP--ALREALTKQGYQLIGSHSGVKLCRWTKSMLRGRGGCYKHTFYGIESHRCMETTPSLACANKCVFCWRHHTNPVGTEWRWKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEEGMTVKHCALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPVTQLYVSVDASTKDSLKKIDRPLFKDFWQRFLDSLKALAVKQ--QRTVYRLTLVKAWNVDELQAYAQLVSLGNPDFIEVKGVTYCGES--SASSLTMAHVPWHEEVVQFVHELVDLIP----EYEIACEHEHSNCLLIAHRKFKIGGEWWTWIDYNRFQELIQEYEDSGGSKTFSAKDYMARTPHWALFGASERGFDPKDTRHQRKNKSKAISGC---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NUM6-1", "uniprot_id": "TYW1B_HUMAN", "id": "Q6NUM6-1", "name": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B", "aln": "------------------------------------------------------------------------------------------------------------MDPSADTWDLSS-PLISLWINRFYIYLGFAVSISLWICVQIVIEMQG-------------------------------------------------FATVLAEA-------VTSLDLPVAIINLKEYDPDDHLIEEVTSKNVCVFLVATYTDGLPTESAEWFCK---WLEEASIDFRFGKTYLKGMRDAVFGLGNSAYASHFNKVGKNVDKWLWMLGVHRVMSRGEGDCDVVKSKHGSIEA-------NFRAWKTKFISQ-----------------------LQALQKGERKKSCG--------GHCKKGKCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFGG---EDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSG-----LFRNMGRNE------DGERRAMITP--ALREALTKQ-----------------VDAPRERSLLQTHILWN-ESHRCMETTPSLACANKCVFCWWHHNNPVGTEWLWKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEEGMTVKHCALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPVTQLYVSVDASTKDSLKKIDRPLFKDFWQQFLDSLKALAVKQ--QRTVYRLMLVKAWNVDELQAYAQLVSLGNPDFIEVKGVTYCRES--SASSLTMAHVPWHEEVVQFVRELVDLIP----EYEIACEHEHSNCLLIAHRKFKIGGEWWTWIDYNRFQELIQEYEDSGGSKTFSAKDYMARTPHWALFGANERSFDPKDTRHQRKNKSKAISGC---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08C92-1", "uniprot_id": "TYW1_DANRE", "id": "Q08C92-1", "name": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1", "aln": "-----------------------------------------------------------------------------------------------------------MSGVLNDVRDYTEGYLQVLWQNRLYVYSTAAVLIGVWFTVNMLFKKKKMVHPVSPLASKSVK--KQEPASEAKKVIYVSGVKV---FYGSQTGTAKGFAKELAED-------VIAQGIQCEVIDMKDFDPEDRLAEECTSKIICVFLVATYTDGQPTESAEWFCK---WLEEASTDFRYGKTYLKGMRYAVFGLGNSVYVGHFNTVSKSIDKWLWMLSAARIMTRGEGDCNVVKSRHGSVQA-------DFQVWKGKFLNR-----------------------LQALAKGE-KKACS--------GNCKKASCKNKKKHK----EEAEDNHSLAEKNNSEEELMESSSDEESSS---EDEKSHGSVIDMEDLGNVMNHMKKAKQRMEEDEEDSQR----VKQNGERKSEC----EEERREMITP--ALRDSLTKQGYKLIGSHSGVKLRRWTKSMLRGRGGCYKHTFYGIESHRCMETTPSLACANKCVFCWRHHTNPVGTEWRWKMDPAEKIIQEAMENHRNMIRQFRGVPGVRPERFEEGLTVKHCALSLVGEPIMYPEINSFLKLLHQQNISSFLVTNAQFPEEIRSLVPVTQLYVSVDASTKDSLKKIDRPLFKDFWQRFLDSLRALGEKQ--QRTVYRLTLVKAWNVDELKAYADLIALGQPDFIEVKGVTYCGES--SASSLTMANVPWHEEVIYFVQQLANLLP----DYEIACEHEHSNCLLLANHKFKVDGEWWTWIDYERFQELIQQYEESGGTKNFSAMDYMAKTPSWAVFGAGERGFDPTDTRFQRKNKTKDISGC---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08960-1", "uniprot_id": "TYW1_YEAST", "id": "Q08960-1", "name": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase", "aln": "----------------------------------------------------------------------------------------------------------------MDGFRVAG-ALVVGALTAAYLYFGGRFSIALVIIVGYGIYCNEASGGSQDSQEKLDLNKQQKKPCCSDKKIADGGKKTGGCCSDKKNGGGKGGGCCSSKGGKKGGCCSSKGGKKGGCCSSKKNIGDNENTATEVEKAVNYPVTVDFTEVFRKPTKKRSSTPKVFSKNSSSNSRVGKKLSVSKKIGPDGLIKSALTISNETLLSSQIYVLYSSLQGAASKAAKSVYDKLKELDELTNEPKLLNLDDLSDFDDYFINVPVENALYVLVLPSYDIDCPLDYFLQTLEENANDFRVDSFPLRKLVGYTVLGLGDSESWPEKFCYQAKRADHWISRLGGRRIFPLGKVCMKTGGSAKIDEWTSLLAETLKDDEPIIYEYDENADSEEDEEEGNGSDELGDVEDIGGKGSNGKFSGADEIKQMVAKDSPTYKNLTKQGYKVIGSHSGVKICRWTKNELRGKGSCYKKSLFNIASSRCMELTPSLACSSKCVFCWRHGTNPVSKNWRWEVDEPEYILENALKGHYSMIKQMRGVPGVIAERFAKAFEVRHCALSLVGEPILYPHINKFIQLLHQKGITSFLVCNAQHPEALRNIVKVTQLYVSIDAPTKTELKKVDRPLYKDFWERMVECLEILKTVQNHQRTVFRLTLVKGFNMGDVSAYADLVQRGLPGFIEVKGATFSGSSDGNGNPLTMQNIPFYEECVKFVKAFTTELQRRGLHYDLAAEHAHSNCLLIADTKFKINGEWHTHIDFDKFFVLLN----SG--KDFTYMDYLEKTPEWALFGNG--GFAPGNTRVYRKDKKKQNKENQETTTRETPLPPIPA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * . *:* . : : : * : : . :: . . *. :: ..* : :.. :*: . : : .. : :::: : * **. . : . ** .*. :.: .. *: . .:. : ::. . : :: :. *:. **:* .. . . * . .. . . . : . . . . . . . * : :* : : :. . . . : . : : . * : *:: . . **** . * :. .: ::. * **** ******:.****** * .***..:* *::* .* *:::*::.* .**:*::****: .*** :.: *:***********:**.** :::**** *::*** ***.* :*.: *******:**.*: ***:****:****:::::.*. * * ****:** *** :*:.::.***:*: * *.******.*:. .* ...*** ::*::** : **: :. : .*::*.** ******:.. ***:.*** * *::.:* *: ** * *: **: :** **:** .* * :** **:*.* . ", "identical_positions": 192, "similar_positions": 206, "identity": "20.62%" }, { "cls_id": "homologset.agr.SGD:S000006129", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NVD3-1", "uniprot_id": "SETD4_HUMAN", "id": "Q9NVD3-1", "name": "SET domain-containing protein 4", "aln": "---------MQKGKGRTSRIRRR----------KLCGSSE---------------------------SRGVNESHKSEFIELRKWLKAR--KFQDSNLAPACFPGTGRGLMSQTSLQEGQMIISLPESCLLTTDTVIRSYLGAYITKWKPPPSPLLALCTFLVSEKHAGHRSLWKPYLEILPKAYTCPVCLEPEVVN-LLPKSLKAKAEE-QRAHVQEFFASSRDFFSSLQPLFAEAVDSIFSYSALLWAWCTVNTRAVYLRPRQRECLSAEPDTCALAPYLDLLNHSPHVQVKAAFNEETHSYEIRTTSRWRKHEEVFICYGPHDNQRLFLEYGFVSVHNPHACVYVSR-------------EILVKY----------LPSTD----------------KQMDKKISILKDHGYIENLTFG-------WDGPS--WRLLTALKLL---------------------CLEAEKFTCWK------------------KVLLGEVISDTNEKTSLDIAQKICYYFIEETN---------------------------------------AVLQKVSHMKDEKEALINQLTLVES-LWTEE-LKILRASAETLHSLQTAFT--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91WC0-1", "uniprot_id": "SETD3_MOUSE", "id": "Q91WC0-1", "name": "Actin-histidine N-methyltransferase", "aln": "MGKKSRVKTQKSGTGATATVSPKEILNLTSELLQKCSSPAPSPGKEWEEYTQIRALVEKIRKKQKGLSVTFDGKREDYFPDLMKWASEN--GASVEGFEMVNFKEEGFGLRATRDIKAEELFLWVPRKLLMTVESAKNSVLGPLYSQDRILQAMGNIALAFHLLCERASPNSFWQPYIQTLPSEYDTPLYFEEEEVR-CLQSTQAIHDVFSQYKNTARQYAYFYKVIQTHPHANKLPLKESFTYEDYRWAVSSVMTRQNQIPTED-----GSRVTLALIPLWDMCNHT-NGLITTGYNLEDDRCECVALQDFQAGDQIYIFYGTRSNAEFVIHSGFFFDNNSHDRVKIKLGVSKSDRLYAMKAEVLARAGIP-TSSVFALHSTEPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNAEFPVSWDNEVKLWTFLEDRASL---------------------LLKTYKTTIEEDKIVLKNPDLSVRATMAIKLRLGEKEILEKAVKSAAVNREYYRKHMEERAPLPRYEESDLGLLEGGVGDSRLPLVLRKLEEEAGVQESLSLTETVSKVKAAENGLVNGENLIPNGTRSEN-ESLSPEESENVTGEESSGSMAKVKERL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08961-1", "uniprot_id": "RKM1_YEAST", "id": "Q08961-1", "name": "Ribosomal lysine N-methyltransferase 1", "aln": "----------MSSDALKALLQWG----------ASFGVIVP------------------------EELKFLYTDLKGIICVCEKDIDNPSIKIPPEIVISRNLPMKFFGLSESTKNINGWLKLFFAKIKFDRDNDTIVDNVRVNDKFKPYLDALPSRLNSPLVWNPSELKRLSSTNIGNSIHEKFEGIFKEWFELVSSSDMFDLERVADDVQTFHNLDELTYEALYEKILKITELQRPTIWYSFPAFLWSHLIFISRAFPEYVLNRN---CPDNSIVLLPIVDLLNHD--YRSKVKWYPENGWFCYEKIGTASQSRELSNNYGGKGNEELLSGYGFVLEDNIFDSVALKVKLPLDVVSTILETEPSLKLPLLSDYTTYAFENKDCVQQEKKATRSATDYINGVTYFINIQNEQCLEPLLDLFTYLSKAEEEDLHDLRARLQGIQMLRNALQSKLNSITGPPATDDSYAIDPYRVYCADVYTKGQKQILKEALTRLKKLEKTMLSENKHQLLTMSKILKNDPAFAETELPSLFSNEDGEEVIFESTYDLLILWILLKTKKNSYPTKYEWVGQQYTNFKQTAYISDDAKAFHTAYFEKQDDVDLAEVDHAIQFVVDNSFTRTSSTTEETILVRK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . .: : . . . :. : * . . . : ** . : : ... : : . . : . : : : . : : . : . * * * : : . ::: *: . :* : : .* * *: ** .. : * :: ** :.* .:. **. .* . * :. * : : ..: . : : : : :. * * :.. : . *: : : : . * : : ::.* : : .:: .: . :.: : ", "identical_positions": 27, "similar_positions": 104, "identity": "4.27%" }, { "cls_id": "homologset.agr.SGD:S000006130", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59241-1", "uniprot_id": "AURKA_RAT", "id": "P59241-1", "name": "Aurora kinase A", "aln": "-------MDRCKENCVSRPVKSTVPFG-PKRVLVTEQIPSQ-----------------HPGSASSGQAQRVLCPSNS-QRVPPQAQKPVAGQKPVL----KQLPAASGPRPASR-LSNPQKSEQPQPAASGNNSEKEQTSIQKTEDSKKRQWTLEDFDIGRPLGKGKFGNVYLAREKQSKFILALKVLFKVQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKL--SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSNGELKIADFGWSVHAP-SSRRTTLCGTLDYQPPEMIEGRMHDEKVDLWSLGVLCYEFLVGMPPFEAHTYQETYRRISRVEFTFPDFVTEGARDLISRLLKHNSSQRLTLAEVLEHPWIKANSSKPPTGHNSKEATSKSS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97477-1", "uniprot_id": "AURKA_MOUSE", "id": "P97477-1", "name": "Aurora kinase A", "aln": "-------MDRCKENCVSRPVKTTVPFG-PKRVLVTEQIPSQ-----------------NLGSASSGQAQRVLCPSNS-QRVPSQAQKLGAGQKPAP----KQLPAASVPRPVSR-LNNPQKNEQ--PAASGNDSEKEQASLQKTEDTKKRQWTLEDFDIGRPLGKGKFGNVYLARERQSKFILALKVLFKTQLEKANVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKL--SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSNGELKIADFGWSVHAP-SSRRTTMCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGMPPFEAHTYQETYRRISRVEFTFPDFVTEGARDLISRLLKHNASQRLTLAEVLEHPWIKANSSKPPTGHTSKEPTSKSS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14965-1", "uniprot_id": "AURKA_HUMAN", "id": "O14965-1", "name": "Aurora kinase A", "aln": "-------MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQ-----------------NPLPVNSGQAQRVLCPSNSSQRIPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKL--SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAP-SSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQN-KESASKQS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NW76-1", "uniprot_id": "AURKB_DANRE", "id": "Q6NW76-1", "name": "Aurora kinase B", "aln": "-------MQN-KENREPR-VQQTPSAG--VGPLRVEMNPDT-----------------HAVSGPG----RVPVKSNS------------------------------------------------------------------------KVLSIDDFDIGRPLGKGKFGNVYLARERKLKVVIALKVLFKSQMVKEGVEHQLRREIEIQSHLRHPNILRFYNYFHDDTRVFLILEYAPRGEMYKELQRY--GRFDDQRTATYMEEVSDALQYCHEKKVIHRDIKPENLLLGYRGELKIADFGWSVHAP-SLRRRTMCGTLDYLPPEMIEGHSHDEKVDLWSIGVLCYECLVGNPPFETASHAETYKRITKVDLQFPKLVSEGARDLISKLLRHSPSMRLPLRSVMEHPWVKANSRRVLPPVCSSEPH-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O88445-1", "uniprot_id": "AURKC_MOUSE", "id": "O88445-1", "name": "Aurora kinase C", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MEPSTSTRKHFTINDFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRH--QKLDQQRTATIIQELSDALTYCHEKKVIHRDIKPENLLLGLNGEVKISDFGWSVHTP-SLRRKTMCGTLDYLPPEMIAQKPYNEMVDLWCIGVLCYELLVGKPPFESSTSSETYRRIRQVDFKFPSSVPAGAQDLISKLLRYHPSERLSLAQVLKHPWVREHSRRVLP-C-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AD76-1", "uniprot_id": "D4AD76_RAT", "id": "D4AD76-1", "name": "non-specific serine/threonine protein kinase", "aln": "----------------------------------MLEISRL-----------------LVSLGYPVPNLELLCQREQVQEPWTVVKSPSESTSLAT-------------------------------------------GQMEPSTSTKKHFTINDFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIGKEGLEHQLRREVEIQSHLQHPNILRLYNYFYDDSRVYLILEYAPRGELYKELQRN--QKLNQQRTATIIEELSDALIYCHRNKVIHRDLKPENLLLGLKGEVKIADFGWSVHTP-SLRRKTMCGTLDYLPPEMIEGKSYNETVDLWCIGVLCYELLVGKPPFESSTSSETCRRICQVDFRFPSSMPAGAQDLISKLLRHHPSERLSLAQVLKHPWVRKHSQRMLPPCAQMAS--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UQB9-1", "uniprot_id": "AURKC_HUMAN", "id": "Q9UQB9-1", "name": "Aurora kinase C", "aln": "-----------------------------------MSSPRA-----------------VVQLGKAQPAGEELATANQTAQ--------------------------------------------------------------QPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKS--EKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTP-SLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSRRVLPPCAQMAS--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O70126-1", "uniprot_id": "AURKB_MOUSE", "id": "O70126-1", "name": "Aurora kinase B", "aln": "--------MAQKENAYPWPYGSKTSQS------GLNTLSQR-----------------VLRKEPATTSALALVNRFNSQSTAAPGQKLAENKS-QG-------------------------------------------STASQGSQNKQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKS--RTFDEQRTATIMEELSDALTYCHKKKVIHRDIKPENLLLGLQGELKIADFGWSVHAP-SLRRKTMCGTLDYLPPEMIEGRMHNEMVDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSVPSGAQDLISKLLKHNPWQRLPLAEVAAHPWVRANSRRVLPPSAL-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O55099-1", "uniprot_id": "AURKB_RAT", "id": "O55099-1", "name": "Aurora kinase B", "aln": "--------MAQKENVYPWPYGSKTSQS------GLNTLPQR-----------------VLRKEPAVTPAQALMNRSNSQSTAVPGQKLTENK---G-------------------------------------------ATALQGSQSRQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKS--GTFDEQRTATIMEELSDALMYCHKKKVIHRDIKPENLLLGLQGELKIADFGWSVHAP-SLRRKTMCGTLDYLPPEMIEGRMHNEMVDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSMPLGAKDLISKLLKHNPSQRLPLEQVSAHPWVRANSRRVLPPSAL-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96GD4-1", "uniprot_id": "AURKB_HUMAN", "id": "Q96GD4-1", "name": "Aurora kinase B", "aln": "--------MAQKENSYPWPYGRQTAPS------GLSTLPQR-----------------VLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENS------------------------------------------------SGTPDILTRH-FTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKS--CTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAP-SLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGF9-1", "uniprot_id": "Q9VGF9_DROME", "id": "Q9VGF9-1", "name": "Aurora kinase", "aln": "MSHPSDHVLRPKENAPHRMPEKSAAVHNMQKNLLLGKKPNSENMAPASKPLPGSSGALIRKPGLGGSNSIASSEGNNFQKPMVPSVKKTTSEFAAPAPVAPIKKPESLSKQKPTAASSESSKELG---AASSSAEKEKTKTETQPQKPKKTWELNNFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFKRQIGESNVEHQVRREIEIQSHLRHPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQPMKRFDERQSATYIQALCSALLYLHERDIIHRDIKPENLLLGHKGVLKIADFGWSVHEP-NSMRMTLCGTVDYLPPEMVQGKPHTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEHISKAASHLISKLLVLNPQHRLPLDQVMVHPWILAHTQ-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKN7-1", "uniprot_id": "AURKB_DROME", "id": "Q9VKN7-1", "name": "Aurora kinase B", "aln": "-----------------------------------MTLSRA-----------------KHANRNHLPHLLAKVPEEHQEPIKNMCLKMMS----------------------------------------------------HDAYGQPYDWSPRDFEMGAHLGRGKFGRVYLARERHSHYLVAMKVMFKEELRKGCVQRQVLREIEIQSRLKHPHILRLLTWFHDESRIYLALEIASEGELFKHLRGAPNHRFDEPRSAKYTYQVANALNYCHLNNVIHRDLKPENILLTSTDDLKLADFGWSAHTP-NNKRRTLCGTLDYLPPEMVDGNSYDDSVDQWCLGILCYEFVVGCPPFESNSTESTYSKIRRMEISYPSHLSKGCKELIGGLLRKESKGRITLVDVMTHYWVKAGMAERELQLQKRERGKENTARN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38991-1", "uniprot_id": "AURK_YEAST", "id": "P38991-1", "name": "Aurora kinase", "aln": "MQRNSLVNIKLNANSPSKKTTTRPNTSRINKPWRISHSPQQRN--------------PNSKIPSPVREKLNRLPVNNKKFLDMESSKIPSPIRKATS---------------------------------------SKMIHENKKLPKFKSLSLDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLH--GPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDAQDLILKLLKYDPKDRMRLGDVKMHPWILRNKPFWENKRL------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*::* **:****.** .* : : *:*:: * :: : :::*. **:***: *.* :: : :*:* *::* :* * ::. *: ::: :: :..** * * . :****:****:*: . :*::***** * . * *:***:** .***: . : . :* *.:*:*.:* :.* .** * :* :: * :. . .** ** . * * .: * *: ", "identical_positions": 78, "similar_positions": 78, "identity": "17.97%" }, { "cls_id": "homologset.agr.SGD:S000006131", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZUX3-1", "uniprot_id": "A0A8I5ZUX3_RAT", "id": "A0A8I5ZUX3-1", "name": "Signal recognition particle subunit SRP72", "aln": "MASGGS-GGVSVPALWSEVNRYGQNSDFTRALKTVNKILQINKDD-VTALHCKVVCLIQNGSFKEALNVINTHTKVLANN--SLSFEKAYCEYRLNR-----------IENALKTIESANQQ--TDKLKELYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTNLSA-VVAAQS-NWEKVVPVSMRVTHTHTHPTAMNEYSYLLSDRHVSLWQENLGLQEGTHELCYNAACALIGQGQLTQAMKILQKAEDLCRRSFSEDSDGTEEDPQAELAIIHGQMAYIMQLQGRIEEALQLYNQIIKLKPTDVALLAVIAN------NIITINKDQNVFDSKKKVKLTNAEGVEFKLSKRQLQAIEFNKALLAMYTNQAEQCRKIASSLQSQSPE-HLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILR------SIEELKHKPGMVS-ALVTMYSHEEDIDSAIEVFTQAIQWYQSHQPKSPAHLSLIREAANFKLKYGRKKEAVSDLEQLWKQNSKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSPGATYIRKKGGKVTGDNQPKEQGQGDLKKKK---KKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGKGTQGATAGASSELDASKTVSSPPTSPRPGSAATMASSTSNIVPPRHQKPAGAPATKKKQQQKKKKGGKSGW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F8VQC1-1", "uniprot_id": "F8VQC1_MOUSE", "id": "F8VQC1-1", "name": "Signal recognition particle subunit SRP72", "aln": "MASGGS-GGVSVPALWSEVNRYGQNSDFTRALKTVNKILQINKDD-VTALHCKVVCLIQNGSFKEALNVINTHTKVLANN--SLSFEKAYCEYRLNR-----------IENALKTIESATQQ--TDKLKELYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTNLSA-VVAAQS-NWEKVVP-------------------------------ENLGLQEGTHELCYNAACALIGQGQLTQAMKILQKAEDLCRRSFSEDSDGAEEDPQAELAIIHGQMAYIMQLQGRTEEALQLYNQIIKLKPTDVALLAVIAN------NIITINKDQNVFDSKKKVKLTNAEGVEFKLSKRQLQAIEFNKALLAMYTNQAEQCRKIAASLQSQSPE-YLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILR------SIEELRHKPGMVS-ALVTMYSHEEDIDSAIEVFTQAIQWYQSHQPKSPAHLSLIREAANFKLKYGRKKEAVSDLEQLWKQNSKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSPGATYIRKKGGKVTGDNQPKEQGQGDLKKKK---KKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGKGTQGATAGASSELDASKAVSSPPTSPRPGSAATISSSASNIVPPRHQKPAGAPATKKKQQQKKKKGGKSGW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76094-1", "uniprot_id": "SRP72_HUMAN", "id": "O76094-1", "name": "Signal recognition particle subunit SRP72", "aln": "MASGGS-GGVSVPALWSEVNRYGQNGDFTRALKTVNKILQINKDD-VTALHCKVVCLIQNGSFKEALNVINTHTKVLANN--SLSFEKAYCEYRLNR-----------IENALKTIESANQQ--TDKLKELYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTNLSA-VVAAQS-NWEKVVP-------------------------------ENLGLQEGTHELCYNTACALIGQGQLNQAMKILQKAEDLCRRSLSEDTDGTEEDPQAELAIIHGQMAYILQLQGRTEEALQLYNQIIKLKPTDVGLLAVIAN------NIITINKDQNVFDSKKKVKLTNAEGVEFKLSKKQLQAIEFNKALLAMYTNQAEQCRKISASLQSQSPE-HLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILR------SIEELKHKPGMVS-ALVTMYSHEEDIDSAIEVFTQAIQWYQNHQPKSPAHLSLIREAANFKLKYGRKKEAISDLQQLWKQNPKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSAGATYIRKKGGKVTGDSQPKEQGQGDLKKKK---KKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGKGTQGATAGASSELDASKTVSSPPTSPRPGSAATVSASTSNIIPPRHQKPAGAPATKKKQQQKKKKGGKGGW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDK7-1", "uniprot_id": "Q9VDK7_DROME", "id": "Q9VDK7-1", "name": "Signal recognition particle subunit SRP72", "aln": "MSKDANPKEALIKAAYADVNKFGNNQEFDKAVKAVNRILGVAPDD-PTALHCKVVCLVQLSKFEEAYKFIEKN----RLS--SLFFEKAYCEYQLNK-----------QQQALKTIDDAGLQPLPPNLKELRTQVLYRLERYDECLDSYRDIIKNTSDEYEEERRTNLSA-VAANLAVDQTKEVP----------------------------------EVPEDTYEQYFNSACIQANRQKYAEAERKLRTSEKLC----LEDECASEEEIIEEVDVIRVQLAYVLQLQGKTKEASSIYADCLRHKPKDAALVAVASN------NLVVVNKDQNVFDSKKKIRAALADACESRLTSRQKQVIALNNCLLALYTNAGDQVQQLSQKLAQTYPQVEFEALLIRCTQLAKDRKHKEAIEQLQKFAAAHKSHEFVSKFAIIQLQLLQGNRKDAIETLL------SLGEAKYKPGVVS-ALVSLYLGTDNKTAASALLKSAVDWYKKNEVSSGDLSDMWRQAAEFHLRGGASETAASSLEELLKLNPNDTKVLAQLVIAYAQFQPKRALELSRKLPKLETLTTASEIDALEAAN--WVMSAKAAKKTANTKVEPSPSTPLEKKKNRNRKRKGKLPKNYNAEVAPDPERWLPKYERTGFRKKRGGARGKDVIKGSQGMASGAADQYDMSSRVNLTKNSP--------------ATPVYQETAPGPRQQHRKGGHKKKKGGRF--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38688-1", "uniprot_id": "SRP72_YEAST", "id": "P38688-1", "name": "Signal recognition particle subunit SRP72", "aln": "-MAKDN-----LTNLLSQLNIQLSQDEHSQVEQTCVKLLDSGCENPADVFRRCLVAVIQQDKYQKALHYLKKFKHIDDKYGRKFALEKLYIFYKLNMPDEFNTLYTAIITDDLDTVLKKDIES-LRGILHVRAQYCYKNGLYQEAFKIYQHLASHNEKDQDSQIELSCNERVPLSVATELMNRSP-------------------------------LVTPMDESSYDLLFNESFIMASVGKYDKAIELLEK----------ALQGATNEGYQNDINTIKLQLSFVLQMVGKTAQSKEILKGLLQELKADSPFSLICQNNLNAFVDFSKYNTNFNLLLRELNVEKLNTFNLQT-FTHEQWSNIQRNVLFLRLFNNVKIHSQESLLSRTFDKYSKLVDNVTLESYKTQAKKLYHHTTKTILSGTDGSTIGILLLTIQLLIIEKEWENAIRIGELFLNESWKSSFEKFNDSQAIVCYILFELYKIKGRNNSKSVLLKKLGSVRVQLSGKIQENIPFWKHVGFELLSMGNAKESKALLREISNFSKGDADVLVDRVVSSDSLDIAQGIDLVRDIDIDKLIQLGVKPLES---------SAKRSKNTAVSKVQKRKVLELKKKRK--IKRLEKFLQGRDTSKLPDPERWLPLRDRSTYRPKKKQQGAKQTQGG--AMNKKSEQALDISKKG---------------------------------KPTVNKKPKNKKKGRK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :::* .: :. :. :: ::* :: .:: :*.::* ..:::* : ::. .: :** * *:** : *.*: . : : .: * *: *:*.: *:.: :...: :.: . . . * : : : * : *.::: :* : . : :* . *.. .::* :: *: *:::::*: *: :: .: :: * : : * :: *.: *:: : ::. : : :: .* . * * :* ::.* : :: . . . : :.. : .: : .: : : . : .: : :: * : *: : . . .:*. *. :* : ::.. . . . . : :... * * : : : *.:: : . * ..*.: : : .: :. * :.: . : . * .* *. .: : *:**: *: *: :. :.. ******** :*: :* :: .: * . : . * *. .* ::**** : ", "identical_positions": 75, "similar_positions": 222, "identity": "10.16%" }, { "cls_id": "homologset.agr.SGD:S000006132", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y221-1", "uniprot_id": "NIP7_HUMAN", "id": "Q9Y221-1", "name": "60S ribosome subunit biogenesis protein NIP7 homolog", "aln": "MRPLTEEETRVMFEKIAKYIGENLQLLVDRPDGTYCFRLHNDRVYYVSEKIMKLAANISGDKLVSLGTCFGKFTKTHKFRLHVTALDYLAPYAKYKVWIKPGAEQSFLYGNHVLKSGLGRITENTSQYQGVVVYSMADIPLGFGVAAKSTQDCRKVDPMAIVVFHQADIGEYVRHEETLT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CXK8-1", "uniprot_id": "NIP7_MOUSE", "id": "Q9CXK8-1", "name": "60S ribosome subunit biogenesis protein NIP7 homolog", "aln": "MRPLTEEETRVMFEKIAKYIGENLQLLVDRPDGTYCFRLHNDRVYYVSEMMLKLAANISGDKLVSLGTCFGKFTKTHKFRLHVTALDYLAPYAKYKVWVKPGAEQSFLYGNHVLKSGLGRITENTSQYQGVVVYSMADIPLGFGVAAKSTQDCRKVDPMAIVVFHQADIGEYVRHEETLT-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WV50-1", "uniprot_id": "NIP7_RAT", "id": "Q9WV50-1", "name": "60S ribosome subunit biogenesis protein NIP7 homolog", "aln": "MRPLTEEETRVMFEKIAKYIGENLQLLVDRPDGTYCFRLHNDRVYYVSEMILKLAANISGDKLVSLGTCFGKFTKTHKFRLHVTALDFLAPYAKYKVWIKPGAEQSFLYGNHVLKSGLGRITENTSQYQGVVVYSMADVPLGFGVAAKSTQDCRKVDPMAIVVFHQADIGEYIRHEETLT-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q503P2-1", "uniprot_id": "NIP7_DANRE", "id": "Q503P2-1", "name": "60S ribosome subunit biogenesis protein NIP7 homolog", "aln": "MRPLTDEETKTMFEKLSKYIGENIKLLIDRPDGTYCFRLHNDRVYYMSEKILKLATNVSRDKLVSVGTCFGKFTKTQKFRLHITALDFLAPYAKFKVWVKPGSEQSFLYGNHIMKSGLGRITENTDKYQGVLVYSMADVPLGFGVAARTTQECRKVDPMAIVVFHQADIGEYIRSEDTLT-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC28-1", "uniprot_id": "Q9VC28_DROME", "id": "Q9VC28-1", "name": "60S ribosome subunit biogenesis protein NIP7 homolog", "aln": "MKRLSDERAKILFEHLSKYIGTNVKHLIDRPDGTYCFREHKDRVYYVSERILKLSECFGYKQLVCVGTCFGKFSKTNKLKFHITALYYLAPYAQYKVWVKPSFEQQFLYGNHIPKTGLGRITENAGQYQGVVVYSMNDLPLGFGVLARSTTDCKTADPMTTVCFHQSDIGEYIRAEDTLF-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08962-1", "uniprot_id": "NIP7_YEAST", "id": "Q08962-1", "name": "60S ribosome subunit biogenesis protein NIP7", "aln": "MRQLTEEETKVVFEKLAGYIGRNISFLVDNKELPHVFRLQKDRVYYVPDHVAKLATSVARPNLMSLGICLGKFTKTGKFRLHITSLTVLAKHAKYKIWIKPNGEMPFLYGNHVLKAHVGKMSDDIPEHAGVIVFAMNDVPLGFGVSAKSTSESRNMQPTGIVAFRQADIGEYLRDEDTLFT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *::*.:: :**::: *** *:. *:*. : .: ** ::*****:.: : **: .. :*:.:* *:***:** *:::*:*:* ** :*::*:*:**. * ******: *: :*::::: :: **:*::* *:****** *::* :.:. :* * *:*:*****:* *:** ", "identical_positions": 74, "similar_positions": 68, "identity": "40.88%" }, { "cls_id": "homologset.agr.SGD:S000006133", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WU56-1", "uniprot_id": "PUS1_MOUSE", "id": "Q9WU56-1", "name": "Pseudouridylate synthase 1 homolog", "aln": "MGFPRL---------WAALLRNWGRWTARPGPRVPGLPPMAGNKVPPALASHQP-DRK------GRGG--WVWEET-EHPAKRVKGGEDEE---PPRKLPKRKIVLLMAYSGKGYHGMQRNLGSSQFRTIEDDLVSALVQAGCIPENHGTDMRKMSFQRCARTDKGVSAAGQVVSLKVWL-IDDILDKINSHLPSHIRILGLKRVTGGFNSKNKCDARTYCYMLPTFAFAHKD------RDVQD----------------------------------------------------------------------ESYRLSAETLQQVNRLLACYKGTHNFHNFTSQKGPREPSARRYILEMYCEEPFVR--EGLEFAVIKVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGEEKVDVPKAPGLGLVLERVHFEKYNQRFGGDGLHEPLDWTQEEGKVTAFKEQYIYPTIVSTERDERSMAQWLNTLPIHNFSGTALG-----------------------------------------------AADTGAKVPSSLEGSEGDGDTD----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KM92-1", "uniprot_id": "PUS1_RAT", "id": "Q4KM92-1", "name": "Pseudouridylate synthase 1 homolog", "aln": "MGFPRL---------WAALLRAWGRWTARPGPRVPGLPPMAGNKVPPALPSHQP-DRK------GRGG--WVWEET-EHPAKRVKGGEDEE---PPRKLPKRKIVLLMAYSGKGYHGMQRNLGSSQFRTIEDDLVSALVQAGCIPENHGTDMRKMSFQRCARTDKGVSAAGQVVSLKVWL-IDDILDKINSHLPSHIRILGLKRVTGGFNSKNKCDARTYCYMLPTFAFAHKD------RDVQD----------------------------------------------------------------------ESYRLSAETLQQVNRLLGCYKGTHNFHNFTSQKGPREPSARRYILEMYCEEPFVR--EGLEFAVIKVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGEEKVDVPKAPGLGLVLERVHFEKYNQRFGSDGLHEPLDWAQEEGKVTAFKEQYIYPTIVSTERDERSMAQWLNTLPIHNFSGTALG-----------------------------------------------ADDTGAKVPSSLEGSEGDGDTD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y606-1", "uniprot_id": "PUS1_HUMAN", "id": "Q9Y606-1", "name": "Pseudouridylate synthase 1 homolog", "aln": "MGLQ-----------LRALLGAFGRWTLRLGPRPSCSPRMAGNAEPPPAGAACPQDRRSCS---GRAGGDRVWEDG-EHPAKKLKSGGDEE---RREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWL-IDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKD------RDVQD----------------------------------------------------------------------ETYRLSAETLQQVNRLLACYKGTHNFHNFTSQKGPQDPSACRYILEMYCEEPFVR--EGLEFAVIRVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGTEKVDVPKAPGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQEEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATALT-----------------------------------------------AGGTGAKVPSPLEGSEGDGDTD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1JIR1-1", "uniprot_id": "E1JIR1_DROME", "id": "E1JIR1-1", "name": "Pseudouridylate synthase 1 homolog", "aln": "MFLRRLLNDYTKAVRLKTLCNPWNRHKSFAAAMSEALDKLEVEKEARKEAKELEGEAVKDANRIKRTLKRKKWVDWKEQDEKDAANGVKRAPFDPADRIKRKKSAILLSYCGANYYGMQRNPG---MQTIEEELFKAMLKHKWITEDSFEQIQISCFQRAARTDKGVSAARQVCSVKLPE-ELD-LEAFNADLPQQIRLFGVERVTKGFNAKDQCNARTYTYTLPTVAFAPFE------EKVDDV--------------------------------------------------------------------HDTFRISPELLQKVKETLKLYEGTKNFHNFTSKKSFLDPSSKRFIMSFTSSEPFRSP-QDIEFVTLKVKGQSFMLHQIRKMVGLAIAIVRGNTTAATLERALTEERLDLPMAPGLGLVLDTVHYERYNDRYGKDGIHNPLTWQAQEAQVQEFIEREIFSQIYKTEAEQRNMLDWIGTLHYHSYDTRTED-----------------------------------------------APPP-SSEDKKVKGGDDDNDE-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12211-1", "uniprot_id": "PUS1_YEAST", "id": "Q12211-1", "name": "tRNA pseudouridine synthase 1", "aln": "-------------------MSEENLRPAYDDQVNEDVYKRGAQSKLTKARKADFDDEKD-----KKKDNDKHIDKRPKSGPRLDENGNPLP---KEPRLPKRKVAVMVGYCGTGYHGMQYNPP---NPTIESALFKAFVEAGAISKDNSNDLKKNGFMRAARTDKGVHAGGNLISLKMIIEDPDIKQKINEKLPEGIRVWDIERVNKAFDCRKMCSSRWYEYLLPTYSLIGPKPGSILYRDIEESKTELPGVLDEDLESKEFWEEFKKDANEKFSTEEIEAILAYVPPARDEFDINEELYQKVKKYKQLENAHRRRYRISAAKLAKFRASTSQYLGAHNFHNFTLGKDFKEPSAIRFMKDIKVSDPFVIGDAQTEWISIKIHGQSFMLHQIRKMVSMATLITRCGCPVERISQAYGQQKINIPKAPALGLLLEAPVFEGYNKRLEQFG-YKAIDFSKYQDEVDKFKMKHIYDKIYKEEVDENVFNAFFSYIDSFNKVTGAQGEETADKSGPAVQKSIFEFLTAKGIPGLTDAPESNKKIKQRKRMEEEEAASKKAEISSTTQSNEPEVQPEAAAN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : . : : .* : ::* .:::.*.* .*:*** * ***. *..*::. *.:: ::: * *.******* *. :: *:*: * : :* .**. **: .::**. .*:.:. *.:* * * *** :: . ..::: :*:*. * :.. * *::****** *. :**: *:: .: .:** *: ::::*****:*******.:. *.: . :.:: :::::* **.***:*: :* **.* * ::.: : : :* * . *: * * ::. : ::. : .. : * :. . :..: : : ", "identical_positions": 92, "similar_positions": 133, "identity": "16.0%" }, { "cls_id": "homologset.agr.SGD:S000006134", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P57784-1", "uniprot_id": "RU2A_MOUSE", "id": "P57784-1", "name": "U2 small nuclear ribonucleoprotein A'", "aln": "MVKLTAELIEQAAQYTNAVRD-----------RELDLRGYKIPVIENLGATLDQFDAIDFSDNEIRKLDGFPLLRRLKTLLVNNNRICRIGEGLDQALPCLTELILTNNSLVELGDLDPLA-SLKSLTYLSILRNPVTNKKHYRLYVIYKVPQVRVLDFQKVKLKERQEAEKMFKGKRGAQLAKDIARRSKTFNPGAGLPTDKK--KGGPSAG-------DVEAIKNAIANASTLAEVERLKGLLQSGQIPG--RERRSGPSDEGEEEIEDDTVTNGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZZR5-1", "uniprot_id": "D3ZZR5_RAT", "id": "D3ZZR5-1", "name": "", "aln": "MVKLTAELIEQAAQYTNAVRD-----------RELDLRGYKIPVIENLGATLDQFDAIDFSDNEIRKLDGFPLLRRLKTLLVNNNRICRIGEGLDQALPCLTELILTNNSLVELGDLDPLA-SLKSLTYLSILRNPVTNKKHYRLYVIYKVPQVRVLDFQKVKLKERQEAEKMFKGKRGAQLAKDIARRSKTFNPGAGLPTDKK--KGGPSAG-------DVEAIKNAIANASTLAEVERLKGLLQSGQIPG--RERRSGPSDEGEEEMEDGTVTNGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09661-1", "uniprot_id": "RU2A_HUMAN", "id": "P09661-1", "name": "U2 small nuclear ribonucleoprotein A'", "aln": "MVKLTAELIEQAAQYTNAVRD-----------RELDLRGYKIPVIENLGATLDQFDAIDFSDNEIRKLDGFPLLRRLKTLLVNNNRICRIGEGLDQALPCLTELILTNNSLVELGDLDPLA-SLKSLTYLSILRNPVTNKKHYRLYVIYKVPQVRVLDFQKVKLKERQEAEKMFKGKRGAQLAKDIARRSKTFNPGAGLPTDKK--KGGPSPG-------DVEAIKNAIANASTLAEVERLKGLLQSGQIPG--RERRSGPTDDGEEEMEEDTVTNGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V4Q8-1", "uniprot_id": "RU2A_DROME", "id": "Q9V4Q8-1", "name": "Probable U2 small nuclear ribonucleoprotein A'", "aln": "MVKLTPELINQSMQYINPCRE-----------RELDLRGYKIPQIENLGATLDQFDTIDLSDNDLRKLDNLPHLPRLKCLLLNNNRILRISEGLEEAVPNLGSIILTGNNLQELSDLEPLV-GFTKLETICLLINPVSTKPNYREYMAYKFPQLRLLDFRKIKQKDRQAAQEFFRTKQGKDVLKEISRKSK-MSAAAAIAAEAGNGKGRGSEGGRLANPQDMQRIREAIKRASSLAEVERLSQILQSGQLPDKFQHEMEAVAQNGAGHNGSGAVAMEY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08963-1", "uniprot_id": "RU2A_YEAST", "id": "Q08963-1", "name": "U2 small nuclear ribonucleoprotein A'", "aln": "-MKFTPSIVIDAPQYYVDHFNGKYNVDKCVILRDLQLETDSESMPSSLKHLTKPTHILDLTNNDLIMIPDLSRRDDIHTLLLGRNNIVEVDGRLLPMN--VQNLTLSNNSIRRFEDLQRLRRAPRTLKNLTLIGNQVCHLANYREHVLRLVPHLETLDFQNVTAEERKSAMSFPRQADGDTLGPVNTAIRDNGSRDKTMEIMNLVVSKMTVER--------RNELKKQLAEATSLEEIARLEKLLSGGV-----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:*..:: :: ** : *:*:*. . . ..* . . :*:::*:: : .:. :: **:..*.* .:. * : .: *:.*.: .: **: * . .* : :: * * :** :: .*::. ***:::. ::*: * .: : * : : . . : . : ::: : .*::* *: **. :*..* ", "identical_positions": 39, "similar_positions": 88, "identity": "14.03%" }, { "cls_id": "homologset.agr.SGD:S000006136", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q32Q54-1", "uniprot_id": "Q32Q54_RAT", "id": "Q32Q54-1", "name": "", "aln": "---------MALLVRVLRKQTSISQWVPICSQLMSVSSTQSQRSKTLSSTSQWLQKNPSGMCVGSEQIVGMDTP-HSRKYHNTSKLSTARDSPQPVEEKVGPFTKIIEAMGFTGPLKYSKWKIKIAALRMYTSCVEKTDFEEFFLRCQMPDTFNSWFLITLLHVWMCLVRMKQEG----RTGKYMCRIIVHFMWEDVEQRG-RVMGVN-SYILKKNMALMTNNFYAAVLGYDEGILSDDHGLAAALWRTFFN-QKCEDPRQLELLVEYVRKQMQYLDSMN------GEDLLLTGEVRWRPLVEKNPQSILKPHAPTYNDEGL----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWU6-1", "uniprot_id": "UQCC1_MOUSE", "id": "Q9CWU6-1", "name": "Ubiquinol-cytochrome c reductase complex assembly factor 1", "aln": "---------MALLVRVLRNQTSISQWVPVCSQLVSVSPTQRQWS----STSQWLQKNQSRVCLGSEQTVGADTA-QNRKYHNTSKLLTTQDFPQPVEEKVGPFTKIIEAMGFTGPLKYSKWKIKIAALRMYTSCVEKTDFEEFFLRCQMPDTFNSWFLITLLHVWMCLVRMKQEG----RTGKYMCRIIVHFMWEDVEQRG-RVMGVN-SYILKKNMALMTNNFYAAILGYDEGILSDDHGLAAALWRTFFN-QKCEDPRQLELLVEYVRKQMQYLDSMN------GEDLLLTGEVRWRPLVEKNPQSILKPHAPTYNDEGL----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NVA1-1", "uniprot_id": "UQCC1_HUMAN", "id": "Q9NVA1-1", "name": "Ubiquinol-cytochrome c reductase complex assembly factor 1", "aln": "---------MALLVRVLRNQTSISQWVPVCSRLIPVSPTQGQGDRALSRTSQWPQMSQSRACGGSEQIPGIDIQ-LNRKYHTTRKLSTTKDSPQPVEEKVGAFTKIIEAMGFTGPLKYSKWKIKIAALRMYTSCVEKTDFEEFFLRCQMPDTFNSWFLITLLHVWMCLVRMKQEG----RSGKYMCRIIVHFMWEDVQQRG-RVMGVN-PYILKKNMILMTNHFYAAILGYDEGILSDDHGLAAALWRTFFN-RKCEDPRHLELLVEYVRKQIQYLDSMN------GEDLLLTGEVSWRPLVEKNPQSILKPHSPTYNDEGL----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRZ7-1", "uniprot_id": "UQCC1_DROME", "id": "Q9VRZ7-1", "name": "Ubiquinol-cytochrome c reductase complex assembly factor 1", "aln": "--------------------MQCTRAVARLAGGLARTAWATQHTYKHRPAILGLLEQPCRLCSST----GVVDN-TNKTKPGTAEAAEG-----------GILKRVLNKVGFT---PNTKARLKVTSHLLYESVADKINYVTFFRDFNLPNTFNSWFLVTELHVWLLLMRSMAEGSETGEDGRFLRNCIVEAMWGDVNTRA-KKLGAHNPSRTRQQIETLSEQFQAALIAYDEGIMSDDRVLACALWRRFFE-MNCDDYAQIERLVKYVRQQASMLDSLP------RDQFIVKPKVAWLELDKCKV--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21560-1", "uniprot_id": "CBP3_YEAST", "id": "P21560-1", "name": "Protein CBP3, mitochondrial", "aln": "MMSVNRFTSGRLPVFLRKSPFYYSRAYLHQTCVFKQNKETAQDSPELLAKSSHLNSKPLDVSNKAPVKTAQNKIPLAHSKYESSKYELPKWKEALGELVIRAFHLDMDRVRAGPVAGSYYYKICKEQGLQYEDEPLSETAKYFYEDLKLPRTFSQWFQITVLHEWILFVRMRAMP---FKYGRNYQQKLVDRTFSDIELRLFEEMKVNSGRIADQYLKDFNTQLRGAIFAYDEGFATDDGTLATAVWRNLFGGRKNIDMVHLESVVRYIYSQLYVLSRLSDREFATGKFKFVPPGVKVEKLTPKQEEELKAKTIAKYEALDKDPKTLPSERSRLSYTN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : . . * . . : . :. : : : :: : :: * . . *: ::* **..** :* ** *: ::* . *: . :*. : *:: * . : .: : : :. :: .*::.****: :** ** *:** :* : * ::* :*.*: .* *. : . :: * * : ", "identical_positions": 38, "similar_positions": 69, "identity": "11.24%" }, { "cls_id": "homologset.agr.SGD:S000006137", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0AB13A7N8-1", "uniprot_id": "A0AB13A7N8_DANRE", "id": "A0AB13A7N8-1", "name": "Bromodomain adjacent to zinc finger domain protein 1A", "aln": "MPLLHKKPFVRQKP-PADLRPDEEVFLCKYTHEIFRTYDEFFERTILCNSLVWSCAVTGKPGLTYQEALESEKKARLSLQN-FPNALAVPLLHLTALTHRSRLHEICDDVYAYVKDRFFPGEMVDITSRSTRQLCKILEVIPPYSNGAVNGHTKHRIEGDSIVISDSDDEPTVTSPKTPSNGKKKKAINPSSFKYRVQPVSPEACEPVIVKVAQMSRKKSIFSRDRLKLLLKQHCEPMHGTIRVKPSSALQYKLAEHSFSHFFPDEPPVFTFSPPGKGRGRPPNNASSTEINYIEEKLKLMQQKEQMMSMEKFRKERDDLIEAKKKEKEDKEKKKEEMKRILEEEKLRRKEERERMKVEKEREREKLKEEKKKYAERLKLWSKPREDMECDDLKELPKPIPVKTRLPPELFGDALMVLEFLHAFGELFDLKDEFPDGVTLEVLEEAVVGSDPEGPLCELLFFFLSAIFQALAEEQEEVAKDQLAEDLSEALDDDADPTQSAISAVASLAAAWPQLHQGCSLKQLDLDSCTLSEILRLHILSSGADCGFTNAKFRYQKQGGFGSTDDPCVELRLSNHGLLKKLSCTSVYDLLPGEKLKILHSMCGKLLTLVSTRDFIEDNADEQRAAKQELRELKAEQHRREREEAAERVRKRKEEKLREQELKLKEKHERLKEEAKNGGQLAGEEMDTSTESQEGHAEQHTEDEEEQPAKSKKVKKTNGTTKEKPSGEVEMKDNLSPEELQLQQLKERELLERIQQAMACTYILPLGRDRLYRRYWIFPSAGALFVEDDFFGLTEDMLEPRPTPEPKIEEVLSAESPVKTDGATEELVLVQNTSPPVNRPNQWYFYSTTEEVEQLIEALNPRGLRESSLKETLTLERGRIFQLMESNAAQRYHHSGESLPETKGSSGKAKVGPQSTVPAECFMENRLRDLLLDIEDRIYQGTLGSIKVMERNSWRAALENGNYELLDPDFKEYGLTDREEEPMEIEENHRVKDRLQELKVEGHSATSTSVSTPQPVNNVVHCLAHALAQVEQGIERKFLKAPLGDEDAKKDQKAKKKDKKKDDDQSSEKDDGSESGRQVKTVQERWRESLLACTSLSQVFLHLSTLERSVAWAKSILNTRCKVCRRKGDAENMLLCDGCGRGYHIFCVRPKLKAVPSEDWFCPECRPKQRLNRINSRQRSSVDSEEEMEDEEESEEEDEEESEEEEESEEEQSEEEEVPKKAAVKLPLQNNKGGRSNSKSKQAESANSTSRSQQNTPKQSQPANKGGSKNSGKKATPVSNGKPPSRAGNRSSARLSLEVISTNDTTGKSEQSSPAAGNAESRKRPITAEVSPKSKIILAPTTTSSSRRSSGRNLGVHELSACELLSVDLVRHEDSWPFMKLVSRTQVPDYYDIIKKPIALSTIREKVNNCEYQTAAEYIEDVELMFSNCLEYNPHNTNEAKAGLRLQAFFHSELQRLGLADRMTPPQKRPRM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08964-1", "uniprot_id": "YP216_YEAST", "id": "Q08964-1", "name": "Putative ISWI chromatin-remodeling complex subunit YPL216W", "aln": "MVLLNRRKIQPKEIGQSADSFSETPWVIKESSERINDYDSDLKKLDFYKRDIFTCEISGKDGLSYFKALKSEEQHREKVRYLLPKELRKAIANFANFSPIRKVGHLVESAFQRFSNRFFIGDTVCLKT----------------------------IQKNALITYKEGEPNLVESPTIENN------------------VTLFLVKDVFQSNGMMESEKGEISAPKLSLYLITECLNRE---------------------------------------------------------------------------SKGAALIVGQNEIKRPESHFSKFIIACFLNEILIKVSNKEHAPWRVKQEYIERYDVNPKCSPNMIDYLPDRMNSSSSELYTPLTIPPESDVEPADWKETSETSETSETSLSKIKAIDDEIS--VSFDHIYDNVN--------------------------------SLAYNDLKGTVDDKELPFTGPSIPFENIS------YLDSSLEYKNID------------------------QKWFKECSQFPTERLLVVYQFLSFFGRFIGLSHFNFDQFLTTIKCTSPEALVDEYVKINFLKTYNSKGSFTNEKPRNEIYNQVTSSNVSQREKANVFN--------------------------ADESQRIPSNFTRNQKMRKFITDKSTEFVMYSIFKGKPLKNDD------------------------MEFQSYEKVNILYIDIVCSLMCLMTDN----------------EPDWNCNLMDNWTEEKRKEEGNKTEIDIAIEKCLNYGDTSWVKLLHNKN----FSNGNWLICLLGILQQNTHMIAYSDVAKCITKKILPLSMN-------------FVNLGDELWDN----FRKRLSIKDKIDVLWVLVDFASNFSSYIKELVDK--------------VPKLCNGIRLKLDSAKKEY------------IKLKRQLKTLTKNRVKLHSNVSMNRYGSDECKGKVNALKVKIAYLMEDIA--FLEAKLIQSDIKR---LEILGKDRNGNRYYWMDSNGSSSAISEKNEELYNCCFLWVQGPSEADINFCLDVDVESLKKWELLAKAKGT-AYATKEVFSIFRSTDGSYYQIAQGENFMIINSNGILMRPTIPAFIDKKIISETPEKLLLSHHQWAFFNDIEDIHMLVDRLDDLRENEGQLKKALTSKMDRIEVSYKQQFKIKRRIECDETFKKNHKLLKNN-EFTFPELKRIETTCTSNGQHFSNMEKISKKLSRTKNDLVLEAILK-DVAHLGECERALLKKQQNLIYPLNFHFEQLRTIDLEFIVETKRKRQE-----------------------------DILTKLLNHQRYKHISHVSGYGISSQRVDKAAHLDVQGILEEIECQLISRRREDEERN-----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **::: : :: : .* :: * : * :. **. ::: : : :::* ::** **:* :**:**:: * .:: :*: * .: ::: :: :: .: :..: ..:*** *: * :.: *: :::: ...: * **. .* *: : *: . . *. :*. :* :*.* * .* . .: ** .::: *. :.: .: : : :* * : .::*: . ::* : : : * : .: : * : ...:* . * . *.: : ::.:: :.**:. *::: : : * . :**. ::**. * .. .. .:: : ..**: ::* : ::: . * : * ** .* : ** .. ::*. * . .:: .: :.: : : ...: :. .::*: : :..: :**:* : .* .:: . : :: ::: ** . *.* :*: : :::. * :: : :.*: : : : * .* :: * : . * : *: * . . * *. : *::*.. .* :: . ::* . : .: :. *: *.*. . : : *:.* :. : ::. :..: . .: : :: *:: : : . * ** **. *** : :* . * : :*: ** .* . .: :. *:.* :* : :.* **:* * :.* *: : .*.::.:: *....*. :. :* :. .:* . *:. :::. : * * ::.* . * : : . . .*: :. :: : *:. : * ::* *. ..: ... :. *: . :. :: .*::.: ::. .. :: :. :: : : : : *: :.. : :*. : : * * .... .:. .** : *: .*:. * **.* . *.: .* . . : :. *:. ... .* * . :. :*.. .:::: : *. *.: . . ::*::. : . :*::* : . . : ... ", "identical_positions": 167, "similar_positions": 458, "identity": "11.35%" }, { "cls_id": "homologset.agr.SGD:S000006138", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MJ94-1", "uniprot_id": "A0A096MJ94_RAT", "id": "A0A096MJ94-1", "name": "", "aln": "----MEATDHKKHRKKHSGPKAEKKKKRHLQDLQLGD-EEDARKRNPKAFAVQSAVRMARSFHRTQDLKTKRHHIPVVDRTPLE-PPPIVVVVMGPPKVGKSTLIRCLIRNFTRQKLSEIRGPVTIVSGKKRRLTIIEC-GCDINVMIDLAKVADLVLMLIDASFGFEMETFEFLNICQVHGFPKIMGVLTHLDSFKHNKQLKKTKKRLKHRFWTEVYPGAKLFYLSGMVHGEYQNQEIHNLGRFITVMKFRPLTWQTSHPYILADRMEDLTNPEDIRTN-IKCDRKVSLYGYLRGAYLKTN--SQIHMPGVGDFVASDVSFLPDPCALP----------------------------EQQKKRCLNEKEKLVYAPLSGVGGVLYDKDAVYVDLGGSHGFQT---VEEAGPTHELVQSLISTHASIDAKMASSRVTLFSDSRPLGSEDVDSQGLWMPKEEKQVDVETGRVRRKAVFGDTEEESGDDDSEGDEDEMSDDDGMENGSSDDEVEEEEGAKSSSCKYTTVRGHKRPKLEEQEEDSEADLPAFADSDDDLERSSGGEEEAEEADESS-ADGASTGERDTGEASSVGGARGARPPAAHQWGPHPDGQKPSPVRKAALTTSDSGHCTAEEAFPSEDESEESE-LSSEEEDSEHKEVG----GTNPQQHRGQKPESENVGDETSDIENLLKEEEDHKEENSSSVETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYG-------TVTE-----DNEDEDGDASEELGGLFRVSQPDKGCK--HKADSLDCS------RFHVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAAKLLAED------EELYGDFEDLETG-DVHKGKPGLDTQSEDIEEEEEVKEETGP-------AEEE-----SAREKHLNKKRKLKELFDAEYDE--------------GESTYFDDLKGEMQRQAQLNQAEFEDQDDETRVQYEGFRPGMYVRIEIENIPCEFVQNFDPHYPIILGGLGNSEGTVGYVQMRLKKHRWYKKILKSRDPVIFSVGWRRFQTIPLYYIEDHNGRQRLLKYTPQHMHCGATFWGPITPQGTGFLAIQSVSGAMP-----EFRIAATGVVLDLDKSIKIVKKLKLTGFPFKIFKNTSFIKGMFNSALEVAKFEGAVIRTVSGIRGQIKKALRAPEGAFRASFEDKLLMSDIVFMRTWYPVSIPAFYNPVTSLLKPVGEKDTWSGMRTTHQLRLAHGIKLKPNKDSLYKPILRQKKHFNSLHIPKALQKALPFKNKPKTQAKAGKVPRDRQRPAVIREPHERKVLALLDALSTIHGQKMKKAKEQRHLHNKEHVKMKQKEEEEKLRRQKDLRKKLFRIQGQKEKRSQKSSLRGAEAT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14692-1", "uniprot_id": "BMS1_HUMAN", "id": "Q14692-1", "name": "Ribosome biogenesis protein BMS1 homolog", "aln": "----MEAKDQKKHRKKNSGPKAAKKKKRLLQDLQLGD-EEDARKRNPKAFAVQSAVRMARSFHRTQDLKTKKHHIPVVDRTPLE-PPPIVVVVMGPPKVGKSTLIQCLIRNFTRQKLTEIRGPVTIVSGKKRRLTIIEC-GCDINMMIDLAKVADLVLMLIDASFGFEMETFEFLNICQVHGFPKIMGVLTHLDSFKHNKQLKKTKKRLKHRFWTEVYPGAKLFYLSGMVHGEYQNQEIHNLGRFITVMKFRPLTWQTSHPYILADRMEDLTNPEDIRTN-IKCDRKVSLYGYLRGAHLKNK--SQIHMPGVGDFAVSDISFLPDPCALP----------------------------EQQKKRCLNEKEKLVYAPLSGVGGVLYDKDAVYVDLGGSHVFQ-----DEVGPTHELVQSLISTHSTIDAKMASSRVTLFSDSKPLGSEDIDNQGLMMPKEEKQMDLNTGRMRRKAIFGD-EDESGDSDDE-EDDEMSEDDGLENGSSDEEAEEEENAEMT-DQYMAVKGIKRRKLELEE-DSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYKEENNDSKETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYG-------TVTE-----DNEEEDDDTLEELGGLFRVNQPDRECK--HKADSLDCS------RFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAAKVLAED------EELYGDFEDLETG-DVHKGKSGPNTQNEDIEK--EVKEEIDP-------DEEE-----SAKKKHLDKKRKLKEMFDAEYDE--------------GESTYFDDLKGEMQKQAQLNRAEFEDQDDEARVQYEGFRPGMYVRIEIENVPCEFVQNFDPHYPIILGGLGNSEGNVGYVQMRLKKHRWYKKILKSRDPIIFSVGWRRFQTIPLYYIEDHNGRQRLLKYTPQHMHCGAAFWGPITPQGTGFLAIQSVSGIMP-----DFRIAATGVVLDLDKSIKIVKKLKLTGFPYKIFKNTSFIKGMFNSALEVAKFEGAVIRTVSGIRGQIKKALRAPEGAFRASFEDKLLMSDIVFMRTWYPVSIPAFYNPVTSLLKPVGEKDTWSGMRTTGQLRLAHGVRLKANKDSLYKPILRQKKHFNSLHIPKALQKALPFKNKPKTQAKAGKVPKDRRRPAVIREPHERKILALLDALSTVHSQKMKKAKEQRHLHNKEHFRAKQKEEEEKLKRQKDLRKKLFRIQGQKERRNQKSSLKGAEGQLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VVC9-1", "uniprot_id": "Q9VVC9_DROME", "id": "Q9VVC9-1", "name": "Bms1-type G domain-containing protein", "aln": "MADDAGQDKRKQHRARQSGVKADKKKLKAKKDSNQKEPELTARQRNPKAFAINSAQRAERNFRRKEDLTAKKQHIPVVDQTPNV-PPPVLIAVVGPPKVGKTTLIKDLIKSFTRTNVTDIKGPITIVTSKKRRITLLEC-NNDVNSMIDVAKCADLVLLLCDASYGFEMEIFEFLNICQVHGMPKIMGVLTHLDMIKNPKQLRKRKKELKHRFWTEVYDGAKLFYLSGLLHGEYLRNEVKNLGRFISVMKFRPLQWRGAHSYLLVDRIEDVTNTDRVRRD-PKCDREVVLYGYVRGVPLKQE--HMVHIAGLGDARIDELNVIPDPCPLP----------------------------GTEKKRSLLEKERLLYAPMSGVGGIVYDKDAVYIELQGSHSHKEQEQTAEAAEQAELVNKLIDKKATIDEQMEQQEFRLFSDAKPIKSKDFRND------------------------QDDEEEDEEAESSENEDDDGEDSGLDAADSEEEQQDE-----------------------------------FDADDWRGENSEEEEDAEEDASSGDEEYQSLGNVKTSNE-------------------------------------------------SDSDDEEARVLASN-------------------------------------------------------------MSWKTNLAQKARDAFLQRHSESKNLMRLVYG-------VYNQSEHSRQEAEAEDDSEEELGGLFRVAAKKQSLK--QSDQDIRDKDERCFFEYQGDATRDWLAEDNKELIKNCFVTGKWKASEDAENLLKMDDMSDAESEVYGDFEDLETG-EQHSGKPKAEDGGESEEENSKPEDSSAPKRKLTRVEEEN-----LTKAELMAKKLKLKAKFDAEYDNSGEGKGEEDNGRITGDHSFYEDLKAEAQRQSELNKSEFAHLDNEFRIQIEGYRPGLYVRLGFKQLPAEFIENFDASYPVLVGALNMTEENVGYVNCKVKKHRWYKKILKTGDPLIISMGWRRFQTVAIYAKVEDNFRQRYLKYTPNHVTCSMTFWGPITPQNTGFLALQTVRQDQEEMRRLGFRIAATGCVTEVDKSSQIMKKLKLVGHPFKIYKKTAFVKDMFNSSLEVAKFEGAKIKTVSGIRGQIKKAHHTPEGSYRATFEDKILLSDIVFCRTWFRVEVPRFYAPVSSLLLPLDQKSQWQGMKTLGQLKRERAVQNAAQPDSMYTTIVRKEKIFRPLTIPKALQRALPYKDKPKLGPENPKAALER--VAVVNSPYEQKVSKMMKMIETNFKDKRQRERMEMKKRIKNYREKKREKMASQERRQKELRKKVSRA---------ISKLRGKQTA--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08965-1", "uniprot_id": "BMS1_YEAST", "id": "Q08965-1", "name": "Ribosome biogenesis protein BMS1", "aln": "----MEQSN-KQHRKAKEKNTAKKK--------------LHTQGHNAKAFAVAAPGKMARTMQRSSDVNERKLHVPMVDRTPEDDPPPFIVAVVGPPGTGKTTLIRSLVRRMTKSTLNDIQGPITVVSGKHRRLTFLECPADDLNAMIDIAKIADLVLLLIDGNFGFEMETMEFLNIAQHHGMPRVLGVATHLDLFKSQSTLRASKKRLKHRFWTEVYQGAKLFYLSGVINGRYPDREILNLSRFISVMKFRPLKWRNEHPYMLADRFTDLTHPELIETQGLQIDRKVAIYGYLHGTPLPSAPGTRVHIAGVGDFSVAQIEKLPDPCPTPFYQQKLDDFEREKMKEEAKANGEITTASTTRRRKRLDDKDKLIYAPMSDVGGVLMDKDAVYIDIGKKNEEPSFVPGQERGEGEKLMTGLQSVEQSIAEKFDGVGLQLFSNGTELHEVADHEG--------------------------MDVESGEESIEDDEGKSKGRTSLRKPRIYGKPVQEE-----------------------------------DADIDNLPSDEEPYTNDDDVQDSEPRMVEIDFNNTGEQG-----------------------------------------AEKLALETDSEFEESE----------------------------------------------------------------DEFSWERTAANKLKKTESKKR--TWNIGKLIYMDNISPEECIRRWRGEDDDSKDESDIEEDVDDDFFRKKDGTVTKEGNKDHAVDLEKFVPYFDTFEKLAKKWKS---VDAIKERFLGAGILGNDNKTKSDSNE----GGEELYGDFEDLEDGNPSEQAEDNSDKESEDEDENEDTNGDDDNSFTNFDAEEKKDLTMEQEREMNAAKKEKLRAQFEIEEGENFKEDDENN-----EYDTWYELQKAKISKQLEINNIEYQEMTPEQRQRIEGFKAGSYVRIVFEKVPMEFVKNFNPKFPIVMGGLLPTEIKFGIVKARLRRHRWHKKILKTNDPLVLSLGWRRFQTLPIYTTTDSRTRTRMLKYTPEHTYCNAAFYGPLCSPNTPFCGVQIVANSDTG---NGFRIAATGIVEEIDVNIEIVKKLKLVGFPYKIFKNTAFIKDMFSSAMEVARFEGAQIKTVSGIRGEIKRALSKPEGHYRAAFEDKILMSDIVILRSWYPVRVKKFYNPVTSLLL--KEKTEWKGLRLTGQIRAAMNLETPSNPDSAYHKIERVERHFNGLKVPKAVQKELPFKS-QIHQMKPQKKKTYMAKRAVVLGGDEKKARSFIQKVLTISKAKDSKRKEQKASQRKERLKKLAKMEEEKSQRDKEKKKEYFAQNGKRTTMGGDDESRPRKMRR-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 356, "similar_positions": 356, "identity": "25.63%" }, { "cls_id": "homologset.agr.SGD:S000006139", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y6B6-1", "uniprot_id": "SAR1B_HUMAN", "id": "Q9Y6B6-1", "name": "Small COPII coat GTPase SAR1B", "aln": "MS--FIFDWIYSGFSSVLQFLGLYKKTGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHVQARRVWKNYLPAINGIVFLVDCADHERLLESKEELDSLMTDETIANVPILILGNKIDRPEAISEERLREMFGLYGQTTGKGSISLKELNARPLEVFMCSVLKRQGYGEGFRWMAQYID", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5HZY2-1", "uniprot_id": "SAR1B_RAT", "id": "Q5HZY2-1", "name": "Small COPII coat GTPase SAR1B", "aln": "MS--FIFDWIYSGFSSVLQFLGLYKKTGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHLQARRVWKNYLPAINGIVFLVDCADHERLLESKEELDSLMTDETIANVPILILGNKIDRPEAISEERLREMFGLYGQTTGKGSVSLKELNARPLEVFMCSVLKRQGYGEGFRWMAQYID", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQC9-1", "uniprot_id": "SAR1B_MOUSE", "id": "Q9CQC9-1", "name": "Small COPII coat GTPase SAR1B", "aln": "MS--FIFDWIYSGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHVQARRVWKNYLPAINGIVFLVDCADHERLLESKEELDSLMTDETIANVPILILGNKIDRPEAISEERLREMFGLYGQTTGKGSVSLKELNARPLEVFMCSVLKRQGYGEGFRWMAQYID", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36536-1", "uniprot_id": "SAR1A_MOUSE", "id": "P36536-1", "name": "Small COPII coat GTPase SAR1A", "aln": "MS--FIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLQMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLMESKVELNALMTDETISNVPILILGNKIDRTDAISEEKLREIKGLYGQTTGKGNVTLKELNARPMEVFMCSVLKRQGYGEGFRWLSQYID", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NR31-1", "uniprot_id": "SAR1A_HUMAN", "id": "Q9NR31-1", "name": "Small COPII coat GTPase SAR1A", "aln": "MS--FIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLVESKVELNALMTDETISNVPILILGNKIDRTDAISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVFMCSVLKRQGYGEGFRWLSQYID", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7ZD40-1", "uniprot_id": "B7ZD40_DANRE", "id": "B7ZD40-1", "name": "small monomeric GTPase", "aln": "MS--FIFDWLYRGFSNVLQLLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELSIAGMTFTTFDLGGHAQARRVWRNYLPAINGIVYLVDCADHERLQEAKIELDALLTDETISNVPILILGNKIDRPEAISEDALRGMFGLYGHTTGKGNVSLKELNLRPMEVFMCSVLKRQGYGEGFRWLSQYID", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VD29-1", "uniprot_id": "Q9VD29_DROME", "id": "Q9VD29-1", "name": "", "aln": "-M--FIWDW----FTGVLGYLGLWKKSGKLLFLGLDNAGKTTLLHMLKDDKLAQHVPTLHPTSEELSIGNMRFTTFDLGGHTQARRVWKDYFPAVDAIVFLIDAWDRGRFQESKNELDSLLTDEALSNCPVLILGNKIDKPGAASEDELRNVFGLYQLTTGKGKVARADLPGRPLELFMCSVLKRQGYGEGFRWLAQYID", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20606-1", "uniprot_id": "SAR1_YEAST", "id": "P20606-1", "name": "Small COPII coat GTPase SAR1", "aln": "MAGWDIFGW----FRDVLASLGLWNKHGKLLFLGLDNAGKTTLLHMLKNDRLATLQPTWHPTSEELAIGNIKFTTFDLGGHIQARRLWKDYFPEVNGIVFLVDAADPERFDEARVELDALFNIAELKDVPFVILGNKIDAPNAVSEAELRSALGLLN-TTGSQRIE----GQRPVEVFMCSVVMRNGYLEAFQWLSQYI-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: * * .** ***::* ***:*************:***:*:*. ** *******:*..: ********* ****:*::*:* ::.**:*:*. * *: *:: **::*:. : : *.:******* . * ** ** ** ***. : **:*:*****: *:** *.*:*::*** ", "identical_positions": 101, "similar_positions": 45, "identity": "50.5%" }, { "cls_id": "homologset.agr.SGD:S000006141", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P53026-1", "uniprot_id": "RL10A_MOUSE", "id": "P53026-1", "name": "Large ribosomal subunit protein uL1", "aln": "MSSKVSRDTLYEAVREVLHG-NQRKRRKFLETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCVLGDQQHCDERKAVDIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENMVAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62907-1", "uniprot_id": "RL10A_RAT", "id": "P62907-1", "name": "Large ribosomal subunit protein uL1", "aln": "MSSKVSRDTLYEAVREVLHG-NQRKRRKFLETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCVLGDQQHCDEAKAVDIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENMVAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62906-1", "uniprot_id": "RL10A_HUMAN", "id": "P62906-1", "name": "Large ribosomal subunit protein uL1", "aln": "MSSKVSRDTLYEAVREVLHG-NQRKRRKFLETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCVLGDQQHCDEAKAVDIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENMVAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6A8X9-1", "uniprot_id": "A0A8I6A8X9_RAT", "id": "A0A8I6A8X9-1", "name": "Ribosomal protein", "aln": "MSSKVSHDTLYEAVREVLHG-NQRKRRKFLETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCVLGDQQHCDEAKVVDIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKVGKFPSLMTHNENMVAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTDDKLVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQHLY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZRE5-1", "uniprot_id": "A0A8I5ZRE5_RAT", "id": "A0A8I5ZRE5-1", "name": "Ribosomal protein", "aln": "MSSKVSRDTLYEAVWEVLHG-NQRKRRKFLETVELQISLKNYDPQKEKHFSGTVRLKSTPRPKFSVCVLGDQQHCDEAKAVDIPDMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPRLNKAGKFPSLLTHNENMGAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PC69-1", "uniprot_id": "RL10A_DANRE", "id": "Q6PC69-1", "name": "Large ribosomal subunit protein uL1", "aln": "-MSKVSRDTLYEAVKEVQAG-SRRKKRKFLETVELQISLKNYDPQKDKRFSGTVRLKTTPRPKFSVCVLGDQQHCDEAKAAELPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENLGTKVDEVKSTIKFQMKKVLCLAVAVGHVKMSEEELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P0CX43-1", "uniprot_id": "RL1A_YEAST", "id": "P0CX43-1", "name": "Large ribosomal subunit protein uL1A", "aln": "-MSKITSSQVREHVKELLKYSNETKKRNFLETVELQVGLKNYDPQRDKRFSGSLKLPNCPRPNMSICIFGDAFDVDRAKSCGVDAMSVDDLKKLNKNKKLIKKLSKKYNAFIASEVLIKQVPRLLGPQLSKAGKFPTPVSHNDDLYGKVTDVRSTIKFQLKKVLCLAVAVGNVEMEEDVLVNQILMSVNFFVSLLKKNWQNVGSLVVKSSMGPAFRLY", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VTP4-1", "uniprot_id": "R10AB_DROME", "id": "Q9VTP4-1", "name": "Large ribosomal subunit protein uL1", "aln": "MASKVSRDTLYEGVNGLLEA-SAKKKRGFLETVELQIGLKNYDPQKDKRFSGTVKLKHIPRPKMKVCILGDQQHCDEAKANNVDFMDAEALKKLNKNKKLVKKLAKSYDAFLASESLIKQIPRLLGPGLNKAGKFPALLSHQESMIGKIEEVKSTIKFQMKKVLCLSVAVGHVGMKSDELAQNVNLSINFLVSLLKKNWQNVRSLHVKSSMGPPQRLY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFE0-1", "uniprot_id": "Q9VFE0_DROME", "id": "Q9VFE0-1", "name": "Large ribosomal subunit protein uL1", "aln": "MVSKVSRDTIYVAVKNILLN-SQAKGPDCLETVELQIGLRDYDPDKCKRFHGSVLLHHLAVPQLKVCVFGDQEHCYKAKAIGVDCLDVEALKKLNKDPKLTKKLSKAYDVFLASESIIKQIPRLLGPGLTNAGKFLTPLARGESMSSKIK-ILSTKKKHMKRMECLSVNVGHVGMHPEELARNIAISINFLVSLLKDNWQNVRSLHIKSSLGVPHQLY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:: . : * : . * *******:.*::***:: *:* *:: * . *::.:*::** . . * : :. : ******: ** ***:* *:.*:*** :***:**:*** *.:.*** : ::: :.: *: : ** * ::*:: **:* **:* * : *. :: :::**:*****.***** :* :**::* . :**", "identical_positions": 84, "similar_positions": 69, "identity": "38.53%" }, { "cls_id": "homologset.agr.SGD:S000006143", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ACD6B5B5-1", "uniprot_id": "A0ACD6B5B5_RAT", "id": "A0ACD6B5B5-1", "name": "Selenoprotein O", "aln": "MASFRAAFGASLAVARTRPQCVGLELQSSAPWSAWA-AAMEPTPRWLARLRFDNRALRALPVETPPPGPEDSLSTPRPVPGACFSRARPAPLRQPRLVALSEPALALLGLEVSEEAEVEAEAALFFSGNALLPGTEPAAHCYCGHQFGQFAGQLGDGAAMYLGEVCTAAG-------------ERWELQLKGAGPTAFSRQADGRKVLRSSIREFLCSEAMFHLGIPTTRAGACVTSESTVMRDVFYDGNPKYEKCTVVLRIAPTFIRFGSFEIFKPPDELTGRAGPS--------------VGRNDIRVQMLDYV----------ISSFYPEIQAAHTCDTDNIQRNAAFFREVTRRTARMVAEWQCVGFCHGVLNTDNMSIVGLTIDYGPFGFLDRYDPDHVCNASDNAGRYTYSKQPQVCRWNLQKLAEALEPELPLVL--AEAILKEEFDTEFQRHYLQKMRKKLGLVRVEKEDE-TLVAKLLETMHQT--GADFTNTFCVLSSFPAEPSDT--------AEFLTQLTSQCASLEELKLAFRPQMDPRQLSMMLMLAQSNPQLFALIGTQAN----VTKELERVEHQSRLEQLSPSELQSKNRDHWETWLQEYRERLDKEKEGVGDIAAWQAERVRIMHANNPKYVLRNYIAQKAIEAAENGDFSEVRRVLKLLESPYHSEE-----------------------EATGPEAVARTTDE--QSSYSSRPPLWAAELCVTCSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBC0-1", "uniprot_id": "SELO_MOUSE", "id": "Q9DBC0-1", "name": "Protein adenylyltransferase SelO, mitochondrial", "aln": "MASVRAAVGASLAVARTRPRCVGLALPSSAPRSAWA-AAMEPTPRWLAGLRFDNRALRELPVETPPPGPEDSLATPRPVPGACFSRARPAPLRRPRLVALSEPALALLGLEASEEAEVEAEAALFFSGNALLPGTEPAAHCYCGHQFGQFAGQLGDGAAMYLGEVCTAAG-------------ERWELQLKGAGPTPFSRQADGRKVLRSSIREFLCSEAMFHLGIPTTRAGACVTSESTVMRDVFYDGNPKYEKCTVVLRIAPTFIRFGSFEIFKPPDEHTGRAGPS--------------VGRDDIRVQLLDYV----------ISSFYPEIQAAHTCDTDNIQRNAAFFREVTQRTARMVAEWQCVGFCHGVLNTDNMSIVGLTIDYGPFGFLDRYDPDHICNASDNAGRYTYSKQPQVCKWNLQKLAEALEPELPLAL--AEAILKEEFDTEFQRHYLQKMRKKLGLIRVEKEEDGTLVAKLLETMHLT--GADFTNTFCVLSSFPADLSDS--------AEFLSRLTSQCASLEELRLAFRPQMDPRQLSMMLMLAQSNPQLFALIGTQAN----VTKELERVEHQSRLEQLSPSDLQRKNRDHWEAWLQEYRDRLDKEKEGVGDTAAWQAERVRVMRANNPKYVLRNYIAQKAIEAAENGDFSEVRRVLKLLESPYHSEE-----------------------EATGPEAVARSTEE--QSSYSNRPPLWAAELCVTUSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BVL4-1", "uniprot_id": "SELO_HUMAN", "id": "Q9BVL4-1", "name": "Protein adenylyltransferase SelO, mitochondrial", "aln": "MAVYRAALGASLAAARLLP--LGRCSPSPAPRSTLSGAAMEPAPRWLAGLRFDNRALRALPVEAPPPGPEGAPSAPRPVPGACFTRVQPTPLRQPRLVALSEPALALLGLGAPPAREAEAEAALFFSGNALLPGAEPAAHCYCGHQFGQFAGQLGDGAAMYLGEVCTATG-------------ERWELQLKGAGPTPFSRQADGRKVLRSSIREFLCSEAMFHLGVPTTRAGACVTSESTVVRDVFYDGNPKYEQCTVVLRVASTFIRFGSFEIFKSADEHTGRAGPS--------------VGRNDIRVQLLDYV----------ISSFYPEIQAAHASDS--VQRNAAFFREVTRRTARMVAEWQCVGFCHGVLNTDNMSILGLTIDYGPFGFLDRYDPDHVCNASDNTGRYAYSKQPEVCRWNLRKLAEALQPELPLEL--GEAILAEEFDAEFQRHYLQKMRRKLGLVQVELEEDGALVSKLLETMHLT--GADFTNTFYLLSSFPVELESPG------LAEFLARLMEQCASLEELRLAFRPQMDPRQLSMMLMLAQSNPQLFALMGTRAG----IARELERVEQQSRLEQLSAAELQSRNQGHWADWLQAYRARLDKDLEGAGDAAAWQAEHVRVMHANNPKYVLRNYIAQNAIEAAERGDFSEVRRVLKLLETPYHCEAG----------------------AATDAEATEADGADGRQRSYSSKPPLWAAELCVTUSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LVN8-1", "uniprot_id": "SELO1_DANRE", "id": "Q1LVN8-1", "name": "Protein adenylyltransferase SelO-1, mitochondrial", "aln": "MASVGSRLTRFYISR------PGVIARRFLAHAGMDDMGVSLSRSSLERLEFDNVALKKLPLDPSTE------PGVRQVRGSCFSRVQPTPLKNPEFVAVSAPALALLGLDA-EEVLKDPLGPEYLSGSKVMPGSEPAAHCYCGHQFGQFAGQLGDGAACYLGEVKAPAG--QSPELLRENPTGRWEIQVKGAGLTPYSRQADGRKVLRSSIREFLCSEAVFALGVPTTRAGSVVTSDSRVMRDIFYDGNPRMERCSVVLRIAPSFIRFGSFEIFKRADEFTGRQGPS--------------YGHDELRTQMLEYV----------IENFYPEIHRNYPDLT---ERNTAFFKEVTVRTARLVAQWQCVGFCHGVLNTDNMSILGLTLDYGPFGFMDRFDPDFICNASDNSGRYSYQAQPAICRWNLARLAEALEPDLPPDR--AEQVL-DEYLPLYNDFYLSNMRKKLGLLRKEEPEDEMLITELMQTMHNT--GADFTNTFRSLSQISCPTQEEAEDESETIKQATELLLHQSASLEELKAANRPSMDPRELAMLVSMAQSNPALFQMISDRGT----VSRQLERLSRLKELMDTTEEQLRVKHTEHWSDWIQKYRQRLARECESGVDVKDVQTERVRVMNNNNPHVVLRNYIAQNAIAAAENGDFSEVQRVLKVLEKPFSVQEGLEQPGWMGRGGAAIPG---ERDETEEEGSNSSGAGARGLVPYDSKPPVWANEICVTUSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1P5M3-1", "uniprot_id": "A0A8M1P5M3_DANRE", "id": "A0A8M1P5M3-1", "name": "Selenoprotein O", "aln": "MCVAYCVLSVESLIF------YRIMLLLSRAAAALISLRMDQSLTPLERLKFNNVALKALPVDSSLE------PGSRTVKAACFSLVKPQALIKPTIVALSGPALALLGLKV-EDVLQDPHAAEYLSGSRLIQGSEPAAHCYCGHQFGQFAGQLGDGAVCYLGEVEVEVGAEQTTDPNRTSPCGRWEIQVKGAGLTPYSRLSDGRKVLRSSIREFLCSEAMFALGIPTTRAGSLVTSDLYVQRDEFYSGNPKPERCSVVLRIAPTFIRFGSFEIFHPLDDFTGRQGPS--------------VGRPDIRAGLLDYV----------IETFYPEIQRGHLDRK---ERNAAFFREVTVRTAKLVALWQSVGFCHGVLNTDNMSILGLTIDYGPFGFMDRFDPEFVCNASDKKGRYTYEAQPYVCRWNLARLAEALGAEIQSIK--AGVIL-DEFMSLYEDFYLGNMRKKLGLLRKQEPEDGELVADMLKTMHIT--GADFTNTFRLLSDISSPVGDPAEKDN--TDSVVELIVDQCALLEELKVANHPTMQPGELEMILSMAETNPEMFNMVANQPE----VTKQLEKIGRLRELLMISEAELKVKQREHWQRWVKQYRKRLAFECNQASDPASVEKERVRFMNSTNPAVVLRNYIAQNAIDAAEKGDFSEVQRVLRVLENPYSVSPDLECPVWSAGKGSGQADGISIKGQEVMENTQRKTAAETHHISYNSKPSEWAKAISVTUSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08968-1", "uniprot_id": "SELO_YEAST", "id": "Q08968-1", "name": "Protein adenylyltransferase SelO, mitochondrial", "aln": "MGEKRTIIKALKNSA------ASHFIKKLTADTSLSSIQEAIN----VVQQYNATDPVRLKLFHTPR---------MVSQGAHFAFCLPTKKPHYKPLLLSQNALDEFNLVQDQDLEKILSGEKVYYSDSIFP----YSTVYSGFQFGSFAAQLGDGRVVNLFDLKDKCSG------------QWQTFQLKGAGMTPFSRFADGKAVLRSSIREFIMSEALHSIGIPSTRAMQLTLLPGTKAQ------RRNQEPCAVVCRFAPSWIRLGNFNLFRWRHDLKGLIQLSDYCIEELFAGGTQFEGKPDFNIFKRDFFPDTETKIDEQVEKDETEVSTMTGDNISTLSKYDEFFRHVVSLNANTVAHWQAYGFANGVLNTDNTSIMGLTIDYGPFAFLDKFEPSFTPNHDDTAKRYSFANQPSIIWWNLQQFAKDLACLLGPEARDLELLLKGELNSVDDALEKTMIERVQKLVELSANEYKYVFTTRYAQIMSQRLGVDLDLEKCMSSTNLKDIEHAAEKAKEFCDVIVEPLLDILQATKVDYNNFFIHLQNYKGPFFIKDKSDTATLFGAFDEEYLGMFFNSKQLQQMAETEEAFAAGEKVFDANGELRLLNEKLQEIRNWTQDYLTLVPPTET-AARASLAKKANPLFVPRSWVLEEVVDDLMYSQRDGLQDPSSELDTSALKKLYLMSVN-------------PYDRTKWDVTLRPELETKWADLSHQDDAKFMMQASCSS---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . : .:: * : . .: *: * . : :* ** :.* . .. :: : *.*.***.**.***** . * :: . :*:**** *.:** :**: *********: ***:. :*:*:*** . : . . * *:** *.*.::**:*.*::*: .: .* * *: ::. ::. :.. .*: .: **:.*. .*. ** **. **.:******* **:***:*****.*:*:::*.. * .*. **:: ** : *** ::*: * : :* * . : :.: *:. . : :.: : *.*: * : : :: : ::: . .. :* . . :::*::: . . : . : . : :. . . ** * *.:: ::.: .: . :: *:.. . .:.. . . : ", "identical_positions": 117, "similar_positions": 169, "identity": "15.68%" }, { "cls_id": "homologset.agr.SGD:S000006146", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BVG4-1", "uniprot_id": "PBDC1_HUMAN", "id": "Q9BVG4-1", "name": "Protein PBDC1", "aln": "MAATSGTDEPVSGELVSVAHALSLPAESYGNDPDIEMAWAMRAMQHAEVYYKLISSVDPQFLKLTKVDDQIYSEFRKNFETLR----IDVLDPEELKSESAKEKWRPFCLKFNGIVEDFNYGTLLRLDCSQGYTEENTIFAPRIQFFAIEIARNREGYNKAVYISVQDKEGEKGVNNGGEKRADSGEEENTKNGGEKGADSGEEKEEGINREDKTDKGGEKGKEADKEINKSGEKAM-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D0B6-1", "uniprot_id": "PBDC1_MOUSE", "id": "Q9D0B6-1", "name": "Protein PBDC1", "aln": "MDAAGESEEPVSGEALSIAHALSHPPESYGNDPDIEMAWAIRAMQHAEVYYKLISSVDPQFLKLTKVDDQIYSEFREIFETLR----VDVLDPEELKSESAKEKWRPFCLKFEGIVEDYNYGTLLRLDCSQGYTEENTIFAPRIQFFAIEIARNREGYNKAVSVSIQDKEGEEGAGN---------KEE----AAEKGADSGGEKEEGANRE------GEK-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V6C3-1", "uniprot_id": "G3V6C3_RAT", "id": "G3V6C3-1", "name": "", "aln": "MDAASESEEPVSGEALSIAHALSYPPESYGNDPDIEMAWAIRAMQHAEVYYKLISSVDPQFLKLTKVDDQIYSEFRENFETLR----IDVLDPEELKSESAKEKWRPFCLKFEGIVEDYNYGTLLRLDCSQGYTEENTIFG--FNFLPLKLLGTGKAITKQFPSVFRTKKERKELTIKKRK----LRKELIVEEKKRKESTEKEKSKKLNKG------GEKVKKPVTQLNPHMSVLLTQPPLVK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VP29-1", "uniprot_id": "Q9VP29_DROME", "id": "Q9VP29-1", "name": "Polysaccharide biosynthesis domain-containing protein", "aln": "------------MEMMHGASLLSRPAEEFGNDTLVEEMWAAKALEHAEVHFNLITSVHPSQLKLTPYDDQIYATFRQDFPDLH----VGRLTDDILKSATAKLKWRQFAEKFN-KLDDYSYGTLMRADASREFSPDNSIFVFRVQFLAIEIARNREGLNDEAY------------------------------EKHKPARKVPEEEQ-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08971-1", "uniprot_id": "YP225_YEAST", "id": "Q08971-1", "name": "Protein PBDC1 homolog", "aln": "--------------------MSTFNAETADNLEDIEKQFAVVAVEQAETYWKLLTSVPGSKLRLTKFDDEIYENFMERFPEYKDVERVKKFTEEELKTKEAKERWRKFFTIFEKKIEDYNFGTLLRTDASAEYGQFTTCFVVRLQFYAFEIARNKHGLNDWIVG-------------------------------QK-----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* .* :* :* *:::**.:::*::** . *:** **:** * : * : : : : **: ** :** * *: ::*:.:***:* *.* : .: * .:* .::: . .. .. .: ", "identical_positions": 36, "similar_positions": 48, "identity": "14.75%" }, { "cls_id": "homologset.agr.SGD:S000006147", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6MG08-1", "uniprot_id": "ABCF1_RAT", "id": "Q6MG08-1", "name": "ATP-binding cassette sub-family F member 1", "aln": "---------------MPKGPKQQ----------PPEPEWIGDGEGTSP--ADKVVKKGKKDKKTKKTFFEELAVEDKQAGEEEKLQKEKEQQQQQQQQ--KKKRDTRKGRRKKDVDDDDDGDERVLMER-----LKQLSVPASDEEDEVPVPVPRGRKKAKGGNVFEA-----LIQDESEEEKEEEEEKPVLKPAKP-----------------------------------------EKNRINKAVA-----------EEP-PGLRNKKGKEEK---SKGKAK--NKPSATDSE---GEDDE-DMTKEKEPPRPGKDKDKKG----AEQGSEEEKEEKEGEVKANDPYAH--------------------------------------------LSKKEKKKLKKQMDYERQVESLKAANAA----------------------------ENDFSVSQAEVSS-------RQAMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYG---LVGPNGKGKTTLLKHIANRALS------------IPPNIDVLLCEQEVVADETPAVQAV-----------LRADTKRLRLLE------------EEKRLQGQLEQGDDT---AAEKLEKVYEELRATG-----------------AAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWR-KTLLIVSHDQGFLDDVCTDIIHLDTQRLHYYRGNYMTFKKMYQQKQ----------------KELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEVLTRKQQKCRRKNQDEESQDPP-ELLKRPREYTVR--FTFPDPPPLSPPVLGLHGVTFG-----------------YEGQKPLFKNLDFGIDMDSRICIVGPNGVGKSTLLLLLTGKLTPTNGEMRKNHRLKIGFFNQQYAEQLHMEETPTEYLQRGFN--LPYQDARKCLGRFGLES---------------HAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVE------------EQSVSQIDGDFDDYKREVLEALGEVMVNRPRD-------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P542-1", "uniprot_id": "ABCF1_MOUSE", "id": "Q6P542-1", "name": "ATP-binding cassette sub-family F member 1", "aln": "---------------MPKGPKQQ----------PPEPEWIGDGEGTSP--ADKVVKKGKKDKKTKKTFFEELAVEDKQAGEEEKLQKEKEQQQQQQQQ--KKKRDTRKGRRKKDVDDDSD--ERVLMER-----LKQLSVPASDEEDEVPAPIPRGRKKAKGGNVFEA-----LIQDDSEEE-EEEEENRVLKPAKP-----------------------------------------EKNRINKAVA-----------EEP-PGLRSKKGKEEK---SKGKAK--SKPAAADSE---GEEEEEDTAKEKEPPQQGKDRDKKE----AEQGSGEEKEEKEGDLKANDPYAN--------------------------------------------LSKKEKKKLKKQMDYERQVESLKAANAA----------------------------ENDFSVSQAEVSS-------RQAMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYG---LVGPNGKGKTTLLKHIANRALS------------IPPNIDVLLCEQEVVADETPAVQAV-----------LRADTKRLRLLE------------EERRLQGQLEQGDDT---AAEKLEKVYEELRATG-----------------AAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWR-KTLLIVSHDQGFLDDVCTDIIHLDTQRLHYYRGNYMTFKKMYQQKQ----------------KELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEVLTRKQQKCRRKNQDEESQEPP-ELLKRPKEYTVR--FTFPDPPPLSPPVLGLHGVTFG-----------------YEGQKPLFKNLDFGIDMDSRICIVGPNGVGKSTLLLLLTGKLTPTNGEMRKNHRLKIGFFNQQYAEQLHMEETPTEYLQRSFN--LPYQDARKCLGRFGLES---------------HAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINDYKGAVIVVSHDARLITETNCQLWVVE------------EQGVSQIDGDFDDYKREVLEALGEVMVNRPRD-------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NE71-1", "uniprot_id": "ABCF1_HUMAN", "id": "Q8NE71-1", "name": "ATP-binding cassette sub-family F member 1", "aln": "---------------MPKAPKQQ----------PPEPEWIGDGESTSP--SDKVVKKGKKDKKIKKTFFEELAVEDKQAGEEEKVLKEKEQQQQQQQQQQKKKRDTRKGRRKKDVDDDGE--EKELMER-----LKKLSVPTSDEEDEVPAPKPRGGKKTKGGNVFAA-----LIQDQSEEE--EEEEKHPPKPAKP-----------------------------------------EKNRINKAVS-----------EEQQPALKGKKGKEEK---SKGKAKPQNKFAALDNE---EEDKEEEIIKEKEPPKQGKEKAKKAEQGSEEEGEGEEEEEEGGESKADDPYAH--------------------------------------------LSKKEKKKLKKQMEYERQVASLKAANAA----------------------------ENDFSVSQAEMSS-------RQAMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYG---LVGPNGKGKTTLLKHIANRALS------------IPPNIDVLLCEQEVVADETPAVQAV-----------LRADTKRLKLLE------------EERRLQGQLEQGDDT---AAERLEKVYEELRATG-----------------AAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWR-KTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQKQ----------------KELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEESQEAP-ELLKRPKEYTVR--FTFPDPPPLSPPVLGLHGVTFG-----------------YQGQKPLFKNLDFGIDMDSRICIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGFN--LPYQDARKCLGRFGLES---------------HAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVE------------EQSVSQIDGDFEDYKREVLEALGEVMVSRPRE-------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYW4-1", "uniprot_id": "Q9VYW4_DROME", "id": "Q9VYW4-1", "name": "ATP-binding cassette sub-family F member 1", "aln": "-------------MSKAKGKKKERF--------DDDEEQLEKVQEKKPPTSKKGGKKGKRGGGGGDSSDEDVTTRNRDNEDLESIASSNQSKQQTAGK--KQAKKGKKGKRNNDWSDEDEKPEKSLPANDLDDEDDDEAPLASKPAAKKPQPSKKNKKNKKKNDDFSDEDKPELDLDDLDNE-EDEVEVVAVKPASK-----------------------------------------KSKKKQQAQQKNMFAMSDDEEDEVADDLPNDSEEEEKEQLSNKAAKESKKEQQKQPEKEVEEQKVEQVLSEKVAAVSLKEKTPEPVPKAEPEPESEPQPDEEADAEVDSKFEESKEAKEK------------------------------------KLTHKEKKKQKKQQEYERQMELMTKKGGAGHSDL-----------------------DNNFTMSQVQKSAG------QKAALEQAVDIKIENFTISAKGNDLFVNANLLIAHGRRYG---LVGPNGHGKTTLLRHIATRAFA------------IPPNIDVLLCEQEVVATDKTAINTI-----------LEADVRRTEMLK------------KADELEKQFVAGDLT---VQEELNDTFAELKAIG-----------------AYSAEARARRILAGLGFSKEMQDRPTNKFSGGWRMRVSLARALYLEPTLLMLDEPTNHLDLNAVIWLDNYLQGWK-KTLLIVSHDQSFLDNVCNEIIHLDQKKLQYYKGNYSMFKKMYVQKR----------------REMIKEYEKQEKRLRELKAHGQSKKAAEKKQKESLTRKQEKNKSKQQKQDEDEGPQELLARPKEYIVK--FRFPEPSQLQPPILGVHNVTFA-----------------FPSQKPLFIKVDFGIDLTSRVAIVGPNGVGKSTFLKLLLGELEPQEGEQRKNHRLHVGRFDQHSGEHLTAEESAAEYLQRLFN--LPHEKARKALGSFGLVS---------------HAHTIKMKDLSGGQKARVALAELCLSAPDVLILDEPTNNLDIESIDALAEAINEYEGGVIIVSHDERLIRETGCTLYVIE------------DQTINEIVGEFDDYRKEVLDSLGEVVNNPSVVANAAVLQ------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08972-1", "uniprot_id": "NEW1_YEAST", "id": "Q08972-1", "name": "[NU+] prion formation protein 1", "aln": "MPPKKFKDLNSFLDDQPKDPNLVASPFGGYFKNPAADAGSNNASKKSSYQQQRNWKQGGNYQQGGYQSYNSNYNNYNNYNNYNNYNNYNNYNKYNGQGYQKSTYKQSAVTPNQSGTPTPSASTTSLTSLNEKLSNLELTPISQFLSKIPECQSITDCKNQIKLIIEEFGKEGNSTGEKIEEWKIVDVLSKFIKPKNPSLVRESAMLIISNIAQFFSGKPPQEAYLLPFFNVALDCISDKENTVKRAAQHAIDSLLNCFPMEALTCFVLPTILDYLSSGAKWQAKMAALSVVDRIREDSANDLLELTFKDAVPVLTDVATDFKPELAKQGYKTLLDYVSILDNLDLSPRYKLIVDTLQDPSKVPESVKSLSSVTFVAEVTEPSLSLLVPILNRSLNLSSSSQEQLRQTVIVVENLTRLVNNRNEIESFIPLLLPGIQKVVDTASLPEVRELAEKALNVLKEDDEADKENKFSGRLTLEEGRDFLLDHLKDIKADDSCFVKPYMNDETVIKYMSKILTVDSNVNDWKRLEDFLTAVFGGSDSQREFVKQDFIHNLRALFYQEKERADEDEGIEIVNTDFSLAYGSRMLLNKTNLRLLKGHRYGLCGRNGAGKSTLMRAIANGQLDGFPDKDTLRTCFVEHKLQGEEGDLDLVSFIALDEELQSTSREEIAAALESVGFDEERRAQTVGSLSGGWKMKLELARAMLQKADILLLDEPTNHLDVSNVKWLEEYLLEHTDITSLIVSHDSGFLDTVCTDIIHYENKKLAYYKGNLAAFVEQKPEAKSYYTLTDSNAQMRFPPPGILTGVKSNTRAVAKMTDVTFSYPGAQKPSLSHVSCSLSLSSRVACLGPNGAGKSTLIKLLTGELVPNEGKVEKHPNLRIGYIAQHALQHVNEHKEKTANQYLQWRYQFGDDREVLLKESRKISEDEKEMMTKEIDIDDGRGKRAIEAIVGRQKLKKSFQYEVKWKYWKPKYNSWVPKDVLVEHGFEKLVQKFDDHEASREGLGYRELIPSVITKHFEDVGLDSEIANHTPLGSLSGGQLVKVVIAGAMWNNPHLLVLDEPTNYLDRDSLGALAVAIRDWSGGVVMISHNNEFVGALCPEQWIVENGKMVQKGSAQVDQSKFEDGGNADAVGLKASNLAKPSVDDDDSPANIKVKQRKKRLTRNEKKLQAERRRLRYIEWLSSPKGTPKPVDTDDEED", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* : . . ... .: *:* . :. . .: : :. . :: :: *. . ::. . * . : :. . *: :. :: : ** . :.: ::* * : . : :: ** . :: .: . : . : . . : *: ..::: :: .:: : :: :.: : : .: : **:. *: ::::. ... **:. : :* *. .. .. . *..: . .:. : *: .*: ::: * : .:: : : : . .:*: * : *: : *. : * : * ::. . * .:**. * : :.. .:****:*::.****: :. :*:*********:. * **::** * ******..*** **.:*** : ::* **:** * : : : ::. :.: : : ::. * *:* . :: . . . *: * . . . * :. * : . : .:: :: : . *. .: :. .:... : . : . : ::.:: :. : . : : . ::: .: :: :*: ** * . *: : .***** .:*.:* *.:*:****** ** :*:.**. **.::.*.*:::**: .:: :::* :* : *: : :. : : . ", "identical_positions": 121, "similar_positions": 284, "identity": "10.12%" }, { "cls_id": "homologset.agr.SGD:S000006148", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DB25-1", "uniprot_id": "ALG5_MOUSE", "id": "Q9DB25-1", "name": "Dolichyl-phosphate beta-glucosyltransferase", "aln": "-------MATLLLQLLGLGVALAAAALILVSIVAFITATKMPPCYQHEEEKFFLNAKGQK--EALPSIWDSPT---KQLSVVVPSYNEEKRLPVMMDEALNYLEKRQKHDCTFTYEVIVVDDGSEDQTSKVALKYCQ---KYGSDKVRVITLVRNRGKGGAVRMGVFSSRGEKILMADADGATKFPDVEKLEKGLSDLQPWPEQM-----AIACGSRAHLEK-ESIAQRSYFRTFLMYGFHFLVWFLCVKGIRDTQCGFKLLTREAAARTFSSLHIERWAFDVELLYIAQCLQIPIAEVAVNWTEIEGSKLVPFWSWLQMGKDLLFIRLRYLTGAWRLKQTRKAS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y673-1", "uniprot_id": "ALG5_HUMAN", "id": "Q9Y673-1", "name": "Dolichyl-phosphate beta-glucosyltransferase", "aln": "-------MAPLLLQLAVLGAALAAAALVLISIVAFTTATKMPALHRHEEEKFFLNAKGQK--ETLPSIWDSPT---KQLSVVVPSYNEEKRLPVMMDEALSYLEKRQKRDPAFTYEVIVVDDGSKDQTSKVAFKYCQ---KYGSDKVRVITLVKNRGKGGAIRMGIFSSRGEKILMADADGATKFPDVEKLEKGLNDLQPWPNQM-----AIACGSRAHLEK-ESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKLFTREAASRTFSSLHVERWAFDVELLYIAQFFKIPIAEIAVNWTEIEGSKLVPFWSWLQMGKDLLFIRLRYLTGAWRLEQTRKMN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NAE9-1", "uniprot_id": "A0A8M1NAE9_DANRE", "id": "A0A8M1NAE9-1", "name": "Dolichyl-phosphate beta-glucosyltransferase", "aln": "MLTEIWRMEFCLCDLLQYSLILALVVLLLVVIAAHVTA-KMVDQTRHEKEKQFLTADGKR--EDFPSLMEPPS---IDLSVVVPSYNEELRLPVMMDEAMDYLEKRQKENPSFTYEVIVVDDGSKDKTTEVAMKYTK---KYGAKKVRVLTLVKNRGKGGAVKMGTLSCRGRLILMADADGATKFADVEKVEEGLESITEKPDNM-----AISCGSRAHLEK-ESVAQRSMFRTFLMYGFHFLVWFFCVRGIKDTQCGFKLFTREAALKTFSSLHVERWAFDVELLFIAQCFDIPIEEVAVNWTEIEGSKLVPFWSWLQMGRDLIFIRLRYLTGAWRLESEKKTQ-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLQ1-1", "uniprot_id": "ALG5_DROME", "id": "Q9VLQ1-1", "name": "Dolichyl-phosphate beta-glucosyltransferase", "aln": "-------MWTCLCQLCFYLLSTLAVAALSIAALVLYKTKPYPNIKRHKDEETFLDPHTIKT-VTFPSLEDSPS---LELSVIVPAYNEEQRLPSMLDECLAFLEQKSAGTPNFTYEVIVVSDGSQDATVSVALGYSK---KHGAEKVRVLELIENRGKGGAVRMGMLSARGRNLLFADADGATKFPDYDKLEVALKQLAPEWRDD-----GIAIGSRAHLEN-DAIATRSFFRTILMHGFHFLVWLFAVRSIRDTQCGFKLFTRTTARKLFTSLHVERWAFDVELLYLAENLKLPMSEVAVRWTEIDGSKLTPFWSWLQMGRDLFMIWVRYLVGAWRIASIQKKEK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40350-1", "uniprot_id": "ALG5_YEAST", "id": "P40350-1", "name": "Dolichyl-phosphate beta-glucosyltransferase", "aln": "----MRALRFLIENRNTVFFTLLVALVLSLYLLVYLFSHTPRPPYPEELKYIAIDEKGHEVSRALPNLNEHQDDEEIFLSVVIPSYNETGRILLMLTDAISFLKEKYGSR----WEIVIVDDGSTDNTTQYCLKICKEQFKLNYEQFRIIKFSQNRGKGGAVRQGFLHIRGKYGLFADADGASKFSDVEKLIDAISKIETSSTDLKTTKPAVAIGSRAHMVNTEAVIKRSMIRNCLMYGFHTLVFIFGIRSIKDTQCGFKLFNRAAILKIFPYLHTEGWIFDVEILILAIRKRIQIEEIPISWHEVDGSKMALAIDSIKMAKDLVIIRMAYLLGIYRDN--KKC--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . : : . : .: : : . . :*.: : ***::*:*** *: *: :.: :*::: :*:::*.*** * * . .: : * . .:.*:: : .*******:: * : **. *:******:**.* :*: .:..: : .:: *****: : ::: ** :*. **:*** **::: ::.*:********:.* : : *. ** * * ****:* :* : : *:.: * *::***:. . ::*.:**.:* : ** * :* :* ", "identical_positions": 92, "similar_positions": 106, "identity": "26.59%" }, { "cls_id": "homologset.agr.SGD:S000006153", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61265-1", "uniprot_id": "STX1B_RAT", "id": "P61265-1", "name": "Syntaxin-1B", "aln": "-MKDRTQELRSAK-DSDDEEEV--VHVD-------------------------------------RDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQEL------EDLTADIKKTANKVRSKLKAIEQSIEQEEGL-NRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGR-TTTNEELEDMLESGKLAIFTDDIKMDSQMT--KQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMII--ICCVVLGVVLASSIGGTLGL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61266-1", "uniprot_id": "STX1B_HUMAN", "id": "P61266-1", "name": "Syntaxin-1B", "aln": "-MKDRTQELRSAK-DSDDEEEV--VHVD-------------------------------------RDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQEL------EDLTADIKKTANKVRSKLKAIEQSIEQEEGL-NRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGR-TTTNEELEDMLESGKLAIFTDDIKMDSQMT--KQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMII--ICCVVLGVVLASSIGGTLGL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61264-1", "uniprot_id": "STX1B_MOUSE", "id": "P61264-1", "name": "Syntaxin-1B", "aln": "-MKDRTQELRSAK-DSDDEEEV--VHVD-------------------------------------RDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQEL------EDLTADIKKTANKVRSKLKAIEQSIEQEEGL-NRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGR-TTTNEELEDMLESGKLAIFTDDIKMDSQMT--KQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMII--ICCVVLGVVLASSIGGTLGL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35526-1", "uniprot_id": "STX1A_MOUSE", "id": "O35526-1", "name": "Syntaxin-1A", "aln": "-MKDRTQELRTAK-DSDDDDDVT-VTVD-------------------------------------RDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEEL------EELMSDIKKTANKVRSKLKSIEQSIEQEEGL-NRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGR-TTTSEELEDMLESGNPAIFASGIIMDSSIS--KQALSEIETRHSEIIKLETSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMII--ICCVILGIIIASTIGGIFG---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32851-1", "uniprot_id": "STX1A_RAT", "id": "P32851-1", "name": "Syntaxin-1A", "aln": "-MKDRTQELRTAK-DSDDDDDVT-VTVD-------------------------------------RDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEEL------EELMSDIKKTANKVRSKLKSIEQSIEQEEGL-NRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGR-TTTSEELEDMLESGNPAIFASGIIMDSSIS--KQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMII--ICCVILGIIIASTIGGIFG---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16623-1", "uniprot_id": "STX1A_HUMAN", "id": "Q16623-1", "name": "Syntaxin-1A", "aln": "-MKDRTQELRTAK-DSDDDDDVA-VTVD-------------------------------------RDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEEL------EELMSDIKKTANKVRSKLKSIEQSIEQEEGL-NRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGR-TTTSEELEDMLESGNPAIFASGIIMDSSIS--KQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMII--ICCVILGIVIASTVGGIFA---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24547-1", "uniprot_id": "STX1A_DROME", "id": "Q24547-1", "name": "Syntaxin-1A", "aln": "MTKDRLAALHAAQSDDEEETEVA-VNVDG------------------------------------HDSYMDDFFAQVEEIRGMIDKVQDNVEEVKKKHSAILSAPQTDEKTKQEL------EDLMADIKKNANRVRGKLKGIEQNIEQEEQQ-NKSSADLRIRKTQHSTLSRKFVEVMTEYNRTQTDYRERCKGRIQRQLEITGR-PTNDDELEKMLEEGNSSVFTQGIIMETQQA--KQTLADIEARHQDIMKLETSIKELHDMFMDMAMLVESQGEMIDRIEYHVEHAMDYVQTATQDTKKALKYQSKARRKKIMIL--ICLTVLGILAASYVSSYFM---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q64704-1", "uniprot_id": "STX3_MOUSE", "id": "Q64704-1", "name": "Syntaxin-3", "aln": "-MKDRLEQLKAKQLTQDDDTDEV-EIAID------------------------------------NTAFMDEFFSEIEETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDDL------EQLTTEIKKRANNVRNKLKSMEKHIEEDE---VRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGK-KTTDEELEEMLESGNPAIFTSGII-DSQIS--KQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKRAMKYQGQARKKLIIII--VVVVVLLGILALIIGLSVGLK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08849-1", "uniprot_id": "STX3_RAT", "id": "Q08849-1", "name": "Syntaxin-3", "aln": "-MKDRLEQLKAKQLTQDDDTDEV-EIAID------------------------------------NTAFMDEFFSEIEETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDDL------EQLTTEIKKRANNVRNKLKSMEKHIEEDE---VRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGK-KTTDEELEEMLESGNPAIFTSGII-DSQIS--KQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKRAMKYQGQARKKLIIII--VIVVVLLGILALIIGLSVGLK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13277-1", "uniprot_id": "STX3_HUMAN", "id": "Q13277-1", "name": "Syntaxin-3", "aln": "-MKDRLEQLKAKQLTQDDDTDAV-EIAID------------------------------------NTAFMDEFFSEIEETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDDL------EQLTTEIKKRANNVRNKLKSMEKHIEEDE---VRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGK-KTTDEELEEMLESGNPAIFTSGII-DSQIS--KQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKKAVKYQSQARKKLIIII--VLVVVLLGILALIIGLSVGLN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q00262-1", "uniprot_id": "STX2_MOUSE", "id": "Q00262-1", "name": "Syntaxin-2", "aln": "-MRDRLPDLTACRTNDDGDT-AV-VI-VE------------------------------------KDHFMDGFFHQVEEIRSSIARIAQHVEDVKKNHSIILSAPNPEGKIKEEL------EDLDKEIKKTANRIRGKLKSIEQSCDQDENG-NRTSVDLRIRRTQHSVLSRKFVDVMTEYNEAQILFRERSKGRIQRQLEITGR-TTTDDELEEMLESGKPSIFISDIISDSQIT--RQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMVNNIERNVVNSVDYVEHAKEETKKAIKYQSKARRKKWIIA--AVAVAVIAVLALIIGLSVGK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50279-1", "uniprot_id": "STX2_RAT", "id": "P50279-1", "name": "Syntaxin-2", "aln": "-MRDRLPDLTACRKSDDGDN-AV-IITVE------------------------------------KDHFMDAFFHQVEEIRSSIARIAQHVEDVKKNHSIILSAPNPEGKIKEEL------EDLNKEIKKTANRIRGKLKAIEQSCDQDENG-NRTSVDLRIRRTQHSVLSRKFVDVMTEYNEAQILFRERSKGRIQRQLEITGR-TTTDEELEEMLESGKPSIFISDIISDSQIT--RQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMVNNIERNVVNSVDYVEHAKEETKKAIKYQSKARRKKWIIA--AVVVAVIAVLALIIGLTVGK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32856-1", "uniprot_id": "STX2_HUMAN", "id": "P32856-1", "name": "Syntaxin-2", "aln": "-MRDRLPDLTACRKNDDGDT-VV-VV--E------------------------------------KDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEEL------EDLNKEIKKTANKIRAKLKAIEQSFDQDESG-NRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGR-TTTDDELEEMLESGKPSIFTSDIISDSQIT--RQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWIII--AVSVVLVAIIALIIGLSVGK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BEN6-1", "uniprot_id": "A0A8M2BEN6_DANRE", "id": "A0A8M2BEN6-1", "name": "", "aln": "-MRDRLADLNVGRHNASEDG-GV-AVSME------------------------------------RNDFMQDFFQKVEEVRRVIEKISSLVDEVKKKYSVILSAPNPDEKTKEEL------EQLTVEIKKHANYVQKSLKSMHQSLPSDEQV-NQASVDARIQKTQYTNLSHKFVEVMTQYNEAQVSFREKSKSRIQRQLEITGK-ITTNEELEEMLETGNPSIFTSDIISDSQIT--RQALNEIESRHQDILRLESSIKELHDMFVDMAMLVETQGEMIDNIEKNVHNAVEYVGQAKVETKKAVRYQTRARR-KWVYG--AICGAVCIIILLLIIITAVYVD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1PT03-1", "uniprot_id": "A0A8M1PT03_DANRE", "id": "A0A8M1PT03-1", "name": "Syntaxin-1A", "aln": "-MKDRTQELRHGKELEEQNEVTMNNKMVI------------------------------------EDGFMDEFFEQVEEIREFIDSLAEKVGEVKRNHSATLASPNPDEKTKTEF------EELMNDIKTLANKVRSRLQHIQQSIEHEEAF-NGQSADVRIRKTQHSTLSRKFVEVMSEYNAAQSEYRERCKGRIQRQLEITGR-KTTKEELETILESDNPSIFTTGVFMDCSIT--KQAMNEIETRHNEIIQLESCIRELQDMFVDLAVLVENQGELINNIETNVSSAQEYVEKAKEETKAAIKIQKTSRTKLILIGGCVSVCVLILIIALIFGLT-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P70452-1", "uniprot_id": "STX4_MOUSE", "id": "P70452-1", "name": "Syntaxin-4", "aln": "-MRDRTHELRQGDNISDDEDEVRVALVVHS-------------------------------GAARLGSPDDEFFQKVQTIRQTMAKLESKVRELEKQQVTILATPLPEESMKQGL------QNLREEIKQLGREVRAQLKAIEPQK-EEADE-NYNSVNTRMKKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSGQSEVFVSNILKDTQVT--RQALNEISARHSEIQQLERSIRELHEIFTFLATEVEMQGEMINRIEKNILSSADYVERGQEHVKIALENQKKARKKKVMIA--ICVSVTVLILAVIIGITITVG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08850-1", "uniprot_id": "STX4_RAT", "id": "Q08850-1", "name": "Syntaxin-4", "aln": "-MRDRTHELRQGDNISDDEDEVRVALVVHS-------------------------------GAARLSSPDDEFFQKVQTIRQTMAKLESKVRELEKQQVTILATPLPEESMKQGL------QNLREEIKQLGREVRAQLKAIEPQK-EEADE-NYNSVNTRMKKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSGQSEVFVSNILKDTQVT--RQALNEISARHSEIQQLERSIRELHEIFTFLATEVEMQGEMINRIEKNILSSADYVERGQEHVKIALENQKKARKKKVMIA--ICVSVTVLILAVIIGITITVG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12846-1", "uniprot_id": "STX4_HUMAN", "id": "Q12846-1", "name": "Syntaxin-4", "aln": "-MRDRTHELRQGDDSSDEEDKERVALVVHP-------------------------------GTARLGSPDEEFFHKVRTIRQTIVKLGNKVQELEKQQVTILATPLPEESMKQEL------QNLRDEIKQLGREIRLQLKAIEPQK-EEADE-NYNSVNTRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSGQSEVFVSNILKDTQVT--RQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINRIEKNILSSADYVERGQEHVKTALENQKKARKKKVLIA--ICVSITVVLLAVIIGVTVVG--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R1Q0-1", "uniprot_id": "STX19_MOUSE", "id": "Q8R1Q0-1", "name": "Syntaxin-19", "aln": "-MKDRLQELKQKTKEIELSRDGQVFVEE------------------------EQGVLVQQAVIYEREPVAERHLHEIQKLQENINSFVDDVQRFGQQQKSLVASMRRFSLLKRDS-------TIAKEIKIQAEHINRALGDVVKEVKKSEVENGPSSVVTRILKSQYAAMFRRFQQTMFLYNDTIALKQEKCKTFIVRQLEVAGK-EVSEEEVNDMLHHGKWEVFNESLLTETSIT--KAQLSEIEQRHKELVNLENQVKDLRDLFIQISLLVEEQGESINSIEVMVNSTKDYVNNTKEKFGLAVKYKKRNPCRALCCCCCPRCGSK----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ASN7-1", "uniprot_id": "A0A8I6ASN7_RAT", "id": "A0A8I6ASN7-1", "name": "Syntaxin-19", "aln": "-MKDRLQELKQKTKEIELSRDSQVFAEE------------------------EQGVLVQQAVIYEREPVAERHLHEIHKLQENINSFVDDVHRFGQQQKSLVASMRRFSLLKRDS-------TITKEIKLQAEHINRALGDVVREVKKSEVENGPSSVITRILKSQYAAMFRRFQQTLFLYNDTIALKQEKCKTFIVRQLEVSGK-EVSEEEVNDMLHHGKWEVFNESLLTETSMT--KAQLSEIEQRHKELVNLENQVKDLRDLFIQISLLVEEQGESINNIEVMVNSTKDYVNNTKEKFGLAVKYKRKNPCRALCCCCCPCCGSK----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N4C7-1", "uniprot_id": "STX19_HUMAN", "id": "Q8N4C7-1", "name": "Syntaxin-19", "aln": "-MKDRLQELKQRTKEIELSRDSHVSTTETE----------------------EQGVFLQQAVIYEREPVAERHLHEIQKLQESINNLADNVQKFGQQQKSLVASMRRFSLLKRES-------TITKEIKIQAEYINRSLNDLVKEVKKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGK-EMSEEDVNDMLHQGKWEVFNESLLTEINIT--KAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLVEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRNPCRVLCCWCCPCCSSK----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AVX8-1", "uniprot_id": "A0A8M3AVX8_DANRE", "id": "A0A8M3AVX8-1", "name": "", "aln": "-MKDRMEELRQQMKASEKLVDSKPFNKEEDEDM------------------DPSSLIGLQAVIFEAEPVLEIFLKDAQGIRDSIEELNSEVSKFNEQQKNFVATMRRLSIMKKES-------NMTRDIKLLAESLHKRLDALSKQAKQTEAELGPNATTSRIQKIQHAALFLQFHQVMRQHNDAILSKQEKCKQFIIRQLEVSGR-EVSEEEVDNMIEQGKWEIFNENIIVDAKIT--RTQLSEIEQRHKELLNLESNMKDLRDLFLDVFMLVEEQGHQIQNIQANVEKTQDYVSVTKEKFKRAARYKKNNPLRRLCCCCCPWFR------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9D3G5-1", "uniprot_id": "STX11_MOUSE", "id": "Q9D3G5-1", "name": "Syntaxin-11", "aln": "-MKDRLAELQELSRSYDQQFPDGDNDFDAP----------------------------REDIVFETDNILESLYRVIQDIQDENQLLLIDVRRLGRQNVRFLTSMRRLSSIKRDT------NSIAKAIKTRGEGIHQKLRSMKELSEQAEARHGAHSAVARISHAQYSALARAFQQAMYEYNQAEMKQRDNCKIRIQRQLEIMGK-DMSGEQIEDMFEQGKWDVFSENLLADLKGA--RAALNEIESRHRELLRLEGRIRDVHELFLQMAVLVEKQEDTLNVIELNVQKTLDYTGEAKAQVRKAVQYKKKNPCRTICCFCCPCVN------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K516-1", "uniprot_id": "A0A0G2K516_RAT", "id": "A0A0G2K516-1", "name": "Syntaxin-11", "aln": "-MKDRLAELQELSRSYDQQFPDGDDDFDAP----------------------------QEDIVFETDHILESLYRVIQDIQDENQLLLIDVRRLGRQNVRFLTSMRRLSSIKRDT------NSIAKAIKTRGEGIHQKLRSMKEMSEQAEAQHGAHSAVARISHAQYSALARAFQQAMYEYNQAEMKQRDNCKIRIQRQLEIMGK-DVSGEQIEDMFEQGKWDVFSENLLADVKGA--RAALNEIESRHRELLRLEGRIRDVHELFLQMAVLVEKQADTLNVIELNVQKTLDYTGEAKAQVRKAVQYKKKNPCRTICCFCCPCVN------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75558-1", "uniprot_id": "STX11_HUMAN", "id": "O75558-1", "name": "Syntaxin-11", "aln": "-MKDRLAELLDLSKQYDQQFPDGDDEFDSP----------------------------HEDIVFETDHILESLYRDIRDIQDENQLLVADVKRLGKQNARFLTSMRRLSSIKRDT------NSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGK-EVSGDQIEDMFEQGKWDVFSENLLADVKGA--RAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32867-1", "uniprot_id": "SSO1_YEAST", "id": "P32867-1", "name": "Protein SSO1", "aln": "MSYNNPYQLETPFEESYELDEGSSAIGAEG-------------------------------------HDFVGFMNKISQINRDLDKYDHTINQVDSLHKRLLTEVNEEQ---------------ASHLRHSLDNFVAQATDLQFKLKNEIKSAQRDGIHDTNKQAQAENSRQRFLKLIQDYRIVDSNYKEENKEQAKRQYMIIQPEATEDEVEAAISDVGGQQIFSQALLNANRRGEAKTALAEVQARHQELLKLEKSMAELTQLFNDMEELVIEQQENVDVIDKNVEDAQLDVEQGVGHTDKAVKSARKARKNKIRCWLIVFAIIVVVVVVVVVPAVVKTR-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q7KVY7-1", "uniprot_id": "STX4_DROME", "id": "Q7KVY7-1", "name": "Syntaxin-4", "aln": "MGKDRLPELLQRSLSTNSSNSSSNGSLLLNVYSGTTEFIIGNTGGNNNSYSVVSQNSHSCSNNNSSTEPKDRSSSKMTQYGSNVDDILNPYTEIRQQLAQIAANLETMNRMAQTVNLRTFNENEMDELHNKNLRLGNQLMTRFNDFKANLPAENDYSLEARMKRTLFYGLHQTFINLWHKNELFLQNYETKVKKNLRLHTKIINS-EASEQEIELLIENKTTKLFVDNFLQETEKE--RQTLREMMDRFNELRRLEKSIEEVHALFMRIQTLVMEQSEVIQRVEFHAQQATLHVDKGADELDQAEQHQKKARKKKIMLIVILAAVLLVLLLVGIYL-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * : :: . . : * . . . : : : : . :* . : : :: *. :: .** : :: :* : * * . :: :: : . . * . ", "identical_positions": 10, "similar_positions": 40, "identity": "2.92%" }, { "cls_id": "homologset.agr.SGD:S000006155", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63081-1", "uniprot_id": "VATL_RAT", "id": "P63081-1", "name": "V-type proton ATPase 16 kDa proteolipid subunit c", "aln": "--MA--DIKNNPEYSSFFGVMGASSAMVFSAMGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANSLTD--GITLYRSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63082-1", "uniprot_id": "VATL_MOUSE", "id": "P63082-1", "name": "V-type proton ATPase 16 kDa proteolipid subunit c", "aln": "--MA--DIKNNPEYSSFFGVMGASSAMVFSAMGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANSLTD--GITLYRSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27449-1", "uniprot_id": "VATL_HUMAN", "id": "P27449-1", "name": "V-type proton ATPase 16 kDa proteolipid subunit c", "aln": "--MS--ESKSGPEYASFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEQIMKSIIPVVMAGIIAIYGLVVAVLIANSLND--DISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QSP4-1", "uniprot_id": "F1QSP4_DANRE", "id": "F1QSP4-1", "name": "V-type proton ATPase proteolipid subunit", "aln": "---M--DTQN-PQYSPFFAVMGASSAMVFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANNIGD--KISLYKSFLHLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTKG--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P23380-1", "uniprot_id": "VATL_DROME", "id": "P23380-1", "name": "V-type proton ATPase 16 kDa proteolipid subunit c", "aln": "--MSSEVSSDNPIYGPFFGVMGAASAIIFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAGALEEPSKYSLYRGFIHLGAGLAVGFSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVAIYLYTK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQG3-1", "uniprot_id": "Q8IQG3_DROME", "id": "Q8IQG3-1", "name": "V-type proton ATPase proteolipid subunit", "aln": "-MATDAADKDKPAYSFFFGSMGAASAIIFSALGAAYGTAKSGTGIAAMAVMRPELIMKSIIPVVMAGIIAIYGLVVSVLIAGSLSD--SYTIRKGYIHLAAGLSVGFAGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVAIYLYTK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTI6-1", "uniprot_id": "Q9VTI6_DROME", "id": "Q9VTI6-1", "name": "V-type proton ATPase proteolipid subunit", "aln": "-MVTAALNEE-PSYAFFLGCTGAAVAIIFTTLGASYGTAVSGVGIAKMAVNRPDMIMKAIIPVVMAGIIAIYGLVVSVLIAGSIGD--DYTMEDSYVHLGAGLSVGLPGLTAGVAIGIAGDAGVRGTAEQPRLFVGMVLILIFAEVLALYGLIVAIYLYTKL--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32842-1", "uniprot_id": "VATL2_YEAST", "id": "P32842-1", "name": "V-type proton ATPase subunit c'", "aln": "MSTQLASNIYAPLYAPFFGFAGCAAAMVLSCLGAAIGTAKSGIGIAGIGTFKPELIMKSLIPVVMSGILAIYGLVVAVLIAGNLSPTEDYTLFNGFMHLSCGLCVGFACLSSGYAIGMVGDVGVRKYMHQPRLFVGIVLILIFSEVLGLYGMIVALILNTRGSE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *. *:. *.: *:::: :**: *** ** *** :.. :*: ***::*****:**:*******:****. : :: .:::*..**.**:. *::* ***:.**.*** .*******::*****:***.***:***: * *: ", "identical_positions": 75, "similar_positions": 47, "identity": "45.73%" }, { "cls_id": "homologset.agr.SGD:S000006156", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y230-1", "uniprot_id": "RUVB2_HUMAN", "id": "Q9Y230-1", "name": "RuvB-like 2", "aln": "MATVTATTKVPEIRDVTRIERIGAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVLEMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALTQAFRRSIGVRIKEETEIIEGEVVEIQIDRPATGTGSKVGKLTLKTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSPHGIPIDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDAFLFNELKGET-MDTS---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WTM5-1", "uniprot_id": "RUVB2_MOUSE", "id": "Q9WTM5-1", "name": "RuvB-like 2", "aln": "MATVAATTKVPEIRDVTRIERIGAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVLEMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALTQAFRRSIGVRIKEETEIIEGEVVEIQIDRPATGTGSKVGKLTLKTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSPHGIPIDLLDRLLIVSTSPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDAFLFNELKGET-MDTS---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AAZ0-1", "uniprot_id": "A0A8I6AAZ0_RAT", "id": "A0A8I6AAZ0-1", "name": "RuvB-like helicase", "aln": "---CEAGRPAPRTPAVQEATPTCAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVLEMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALTQAFRRSIGVRIKEETEIIEGEVVEIQIDRPATGTGSKVGKLTLKTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSPHGIPIDLLDRLLIVSTSPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDAFLFNELRKET-MGSTPGGQPGRRTEAKRSSR-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P83571-1", "uniprot_id": "RUVB2_DANRE", "id": "P83571-1", "name": "RuvB-like 2", "aln": "MAAQVATTKVPEVRDITRIERIGAHSHIRGLGLDDALEPRQVSQGMVGQLASRRAAGLILEMIKDGQIAGRAVLIAGQPGTGKTAIAMGIAQSLGPDTPFTALAGSEIFSLEMSKTEALSQAFRKAIGVRIKEETEIIEGEVVEIQIDRPATGTGAKVGKLTLKTTEMETIYDLGTKMIESLSKERVQAGDVITIDKATGKISKLGRSFTRARDYDAMGAQTQFVQCPEGELQKRKEVVHTVSLHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVSEWREEGKAEIIPGVLFIDEVHMLDIECFSFLNRALESDLSPVLIMATNRGITRIRGTNYQSPHGIPIDMLDRLLIIATTPYTEKETRQILKIRCEEEDVELSEEAHTVLTRIGQETSLRYAIQLISTAGLVCRKRRGTEVQVEDIKRVYSLFLDEARSSQYMKEYQDSFLFNETQTSQ-MDTS---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3K3-1", "uniprot_id": "RUVB2_DROME", "id": "Q9V3K3-1", "name": "RuvB-like helicase 2", "aln": "----MAETEKIEVRDVTRIERIGAHSHIRGLGLDDVLEARLVSQGMVGQKDARRAAGVVVQMVREGKIAGRCILLAGEPSTGKTAIAVGMAQALGTETPFTSMSGSEIYSLEMSKTEALSQALRKSIGVRIKEETEIIEGEVVEIQIERPASGTGQKVGKVTLKTTEMETNYDLGNKIIECFMKEKIQAGDVITIDKASGKVNKLGRSFTRARDYDATGAQTRFVQCPEGELQKRKEVVHTVTLHEIDVINSRTHGFLALFSGDTGEIKQEVRDQINNKVLEWREEGKAEINPGVLFIDEVHMLDIECFSFLNRALESDMAPVVVMATNRGITRIRGTNYRSPHGIPIDLLDRMIIIRTVPYSEKEVKEILKIRCEEEDCIMHPDALTILTRIATDTSLRYAIQLITTANLVCRRRKATEVNTEDVKKVYSLFLDENRSSKILKEYQDDYMFSEITEEVERDPAAGGGAKRRVEGGGGDAQPMEH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12464-1", "uniprot_id": "RUVB2_YEAST", "id": "Q12464-1", "name": "RuvB-like protein 2", "aln": "--MSIQTSDPNETSDLKSLSLIAAHSHITGLGLDENLQPRPTSEGMVGQLQARRAAGVILKMVQNGTIAGRAVLVAGPPSTGKTALAMGVSQSLGKDVPFTAIAGSEIFSLELSKTEALTQAFRKSIGIKIKEETELIEGEVVEIQIDRSITG-GHKQGKLTIKTTDMETIYELGNKMIDGLTKEKVLAGDVISIDKASGKITKLGRSFARSRDYDAMGADTRFVQCPEGELQKRKTVVHTVSLHEIDVINSRTQGFLALFTGDTGEIRSEVRDQINTKVAEWKEEGKAEIVPGVLFIDEVHMLDIECFSFINRALEDEFAPIVMMATNRGVSKTRGTNYKSPHGLPLDLLDRSIIITTKSYNEQEIKTILSIRAQEEEVELSSDALDLLTKTGVETSLRYSSNLISVAQQIAMKRKNNTVEVEDVKRAYLLFLDSARSVKYVQENESQYIDDQGNVQISIAKSADPDAMDTTE-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ***** *****: *:.* .*:***** :*****::::*:::* ****.:*:** *.*****:*:*::*:** :.***:::****:***:******:**:*::**::******:**********:*. :* * * **:*:***:*** *:**.*:*: : *::: *****:****:**:.******:*:***** *::*:*****:******* *****:***********:******:******:.***:*** ** **:******* ***************.***:*****.:::*:::******::: ***.*:****:*:*:*** :*: * .*.*:: : ** **.:**: : :* :**: . :*****: :**:.* :. :*: . *:.:*:*:.* ****. ** : ::* :. :: .: . : ", "identical_positions": 257, "similar_positions": 129, "identity": "52.99%" }, { "cls_id": "homologset.agr.SGD:S000006157", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P57760-1", "uniprot_id": "STK16_RAT", "id": "P57760-1", "name": "Serine/threonine-protein kinase 16", "aln": "----------MGHALCVCSRGTVIIDNKRYLFVQKLGEGGFSYVDLVEG----------LHDGHFYALKRILCHEQQDQEEAQREADMHRLFQHPNILRLMAYSLKERG-----AKHEAWLLLPFFKRGTLWNEIERLKDQGNFLTEDQILPLLLGICRGLEAIHAKG----------------------------------------------YAHRDLKPTNILLGDEGQPVLMDLGSMNQACIQVEGSRQALALQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQK-GDSVALAVQN-DLSIPQSPRHSSALRQLLASMMTVDPQQRPHIPVLLSQLEALQPPAPGQHTTQI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88697-1", "uniprot_id": "STK16_MOUSE", "id": "O88697-1", "name": "Serine/threonine-protein kinase 16", "aln": "----------MGHALCVCSRGTVIIDNKRYLFVQKLGEGGFSYVDLVEG----------LHDGHFYALKRILCHEQQDQEEAQREAEMHRLFQHPNILRLMAYSLKERG-----AKHEAWLLLPFFKKGTLWNEIERLKDQGSFLTEDQILPLLLGISRGLEAIHAKG----------------------------------------------YAHRDLKPTNILLGDEGQPVLMDLGSMNQACIQVEGSRQALALQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQK-GDSVALAVQN-ELSIPQSPRHSSALRQLLSSMMTVDPQQRPHIPVLLSQLEALQPPAPGQHTTQI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75716-1", "uniprot_id": "STK16_HUMAN", "id": "O75716-1", "name": "Serine/threonine-protein kinase 16", "aln": "----------MGHALCVCSRGTVIIDNKRYLFIQKLGEGGFSYVDLVEG----------LHDGHFYALKRILCHEQQDREEAQREADMHRLFNHPNILRLVAYCLRERG-----AKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEAIHAKG----------------------------------------------YAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQK-GDSVALAVQN-QLSIPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQLEALQPPAPGQHTTQI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VI84-1", "uniprot_id": "Q9VI84_DROME", "id": "Q9VI84-1", "name": "non-specific serine/threonine protein kinase", "aln": "MQSIGWTLIMKRGCLFSCRKETLNINGSRYTIRERLATGGFSLIDLGEN----------ASTRRSYAIKRITCHSIDDQNIALREIENCRKIDSENVIRVVDYELKGQADIVINTTSTLFIVLPYYKHGSLADHLQLRSRKQDHMPEAQILQIFLGVCEGLKAIHEAMP-------------------------------------------VPLAHRDLKTANICLSDSFEPIIVDLGSMTEARLQIVGQTDAQRLQDEAEERSSIVYRAPELFTVKTYCTIDERTDIWSLGCVLYAMCYFNSPYDPIYER-GDSVALAVLSGNINIPEDSIYTEDMHELIKYMLRTDPMERPFVFSVIERTHDLIQKLEGRL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12003-1", "uniprot_id": "ENV7_YEAST", "id": "Q12003-1", "name": "Serine/threonine-protein kinase ENV7", "aln": "MISIVLELFQNLCCCRGFSDATIRVNDKRYRIQRLLGEGGMSFVYLVQLSKNSLIIDNGIATPELYALKKIICPSVESISNGMREIENYKRFQSPYVIKSIDSQVMQEKD----GSKTIYIVLPYYSLGSLQDSINRRLLEGTFVSEAECVRIMLGVTRGLLCLHDPASRQDNATSRVNVDAVSMTYSDETAMLLEDTPLEMDMLSSNSAGSIAYAHRDITPSNILFSSDGLPVIGDLGSCSQADITIENRHQLSELQEWVNDNCTLPYTPPELLNLKLNQVLSSKVDIWSLGCTFYTLMFGISPFEREEQIHGASLTYAINTGKYSFPRNSRFSEGLLSVIKKCIQVDPIQRPTTSQLLNLLQDLDT----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *: ::..** : . *. **:* : * : . **:*:* * . :. . . ** : : :: ::: : : . . :::**::. *:* : :: : .:.* : : ::**: .** .:* ****:..:** :... *:: **** .:* : : . : **: . :..:: * .***:.:: .:..:.*:*****.:*:: : .*:: : * *:: *: . . .:*... .:. : .:: : .** :** ::. . * ", "identical_positions": 60, "similar_positions": 121, "identity": "15.87%" }, { "cls_id": "homologset.agr.SGD:S000006158", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99L45-1", "uniprot_id": "IF2B_MOUSE", "id": "Q99L45-1", "name": "Eukaryotic translation initiation factor 2 subunit 2", "aln": "MS---GDEMIFDPTMSKKKKKKKKPFMLDEEGDAQTEETQPSETKEVEPEPTEEKDVDADEEDSRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEAIKDVKIE--SDAQEPAEPEDDLDIMLGNKKKKKKNVKFPEEDEILEKDEA-LEDEDSKKDDGISFSSQT--AWAGSERDYTYEELLNRVFNIMREKNPDMVAGEK-RKFVMKPPQVVRVGTKKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTILQKDT--RLYFLQCETCHSRCSVASIKTGFQAVTGKRAQLRAKAN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20042-1", "uniprot_id": "IF2B_HUMAN", "id": "P20042-1", "name": "Eukaryotic translation initiation factor 2 subunit 2", "aln": "MS---GDEMIFDPTMSKKKKKKKKPFMLDEEGDTQTEETQPSETKEVEPEPTEDKDLEADEEDTRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGVKDLKIE--SDVQEPTEPEDDLDIMLGNKKKKKKNVKFPDEDEILEKDEA-LEDEDNKKDDGISFSNQTGPAWAGSERDYTYEELLNRVFNIMREKNPDMVAGEK-RKFVMKPPQVVRVGTKKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTILQKDT--RLYFLQCETCHSRCSVASIKTGFQAVTGKRAQLRAKAN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41375-1", "uniprot_id": "IF2B_DROME", "id": "P41375-1", "name": "Eukaryotic translation initiation factor 2 subunit 2", "aln": "MD---AEDG-FDPTLLKKKKKKKTTFDLD------AALGLEDDTKKEDPQ----------DEASAEGGAAAEEDNLDLESFGKKKKKKKKPFNMDEIEAAIPSFGGDDVAASEEPEEEEINLDMDFSMAKKKKKSKKKELDELFADQADD-DKSEDKENDEDNSS------TWFGSDRDYTYDELLKRVFEIILDKNPDMAAGRK-PKFVMRPPQVLRVGTKKTSFANFMDIAKTLHRLPKHLLDFLLAELGTSGSMDGNQQLIIKGRFQPKQIENVLRRYIKEYVTCHTCRSPETILQKDT--RLFFLQCESCGSRCSVASIKSGFQAVTGKRAAIRAKTT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P09064-1", "uniprot_id": "IF2B_YEAST", "id": "P09064-1", "name": "Eukaryotic translation initiation factor 2 subunit beta", "aln": "MSSDLAAELGFDPALKKKKKTKK---------------VIPDDF-----------------DAAVNGKENGSGDDL-FAGLKKKKKKSKSVSADAEAEK--------------EPTDDIAEALGELSLKKKKKKTKDSSVDAFEKELAKAGLDNVDAESKEGTPSAN----SSIQQEVGLPYSELLSRFFNILRTNNPELAGDRSGPKFRIPPPVCLRDG-KKTIFSNIQDIAEKLHRSPEHLIQYLFAELGTSGSVDGQKRLVIKGKFQSKQMENVLRRYILEYVTCKTCKSINTELKREQSNRLFFMVCKSCGSTRSVSSIKTGFQATVGKRRRM-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . : ***:: ****.** .: : : : . *:* : . *****.*. * * ** : : :. *****. . : : . .. * :..:. . : .: . .*.***.*.*:*: :**::..... ** : ** :* * *** * *: **.: *** *:**: :*:********:**:::*:***:** **:******** *****:**:* :* *::: **:*: *::* * **:***:****..*** : ", "identical_positions": 111, "similar_positions": 83, "identity": "32.46%" }, { "cls_id": "homologset.agr.SGD:S000006160", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C0J6-1", "uniprot_id": "SWAHC_MOUSE", "id": "Q8C0J6-1", "name": "Ankyrin repeat domain-containing protein SOWAHC", "aln": "MEGSLELSSEAILRFLAERGGRAGHSELVQHFRDVLGGQREQRTRARERFKELVNAVATVRTDPADGTKYVHLKKRFCTGDSPPLEAKLPREPPRIEVTEEPQVPDLAAEPCEGSQLQEANPQLSLGLGGEVSDQEPPAPAQGGAQGKDSPPQEVEAVSWASGPGSSENLKLPPQGEAEGGSSPSGPNTPRSARQNFRDLVLGSSPQLKRSVGPGDGNAGGRSRGGGDSDTASLASSSAEEESSVGASVTLDPLDHAWMLSASEGKWDSLEGLLTCEPGLLSKRDFITGFTCLHWAAKHGRQELLAMLVNFATKHQLPVNINAKSSGGYTALHLAAMHGHVEVVKLLVGAYDADVDIRDYSGRKASQYLSESIAEEIKNLVGALDEDDGDSPAARGGGRWRLSKVLPSHITHKLSPVVEDGAELHHHVPEGWTGGSKAKDSGRKASGSSSGRMKPRLNKIRFRTQIIHTTPSFRDAKPTLEEGEEEEEEEEERSLRGYSSSFKLRPKSNVFG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46683-1", "uniprot_id": "YAR1_YEAST", "id": "P46683-1", "name": "Ankyrin repeat-containing protein YAR1", "aln": "-----------------------------------------------------------------------------------------------------------------------------MGLHSEPLDQE-----------------DQDTIILDARAGDLD-----------------------SLKDIFTTLVS-----------------------------PELLSTCKESESDS----------TALHMAAANGHIETVR-------------------------------YILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYF------------------------------------------LKKYDVEPEDDEEDTQTEGKNSVQITKG------------TEIEQVT---KEATEALREETEKLNINKD--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** .* *** : ::: : .*. : * :: * ** ..* *:. *.**. * ::*::*: :::. :* : . : .:* . :* .. * **** *:::*:::***** . *:** **: *:.* .:* **::. . *::: * . ..:: .*::: :.* *:* :.* ::*. :*.* *: : ::: ", "identical_positions": 55, "similar_positions": 81, "identity": "10.74%" }, { "cls_id": "homologset.agr.SGD:S000006161", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07901-1", "uniprot_id": "HS90A_MOUSE", "id": "P07901-1", "name": "Heat shock protein HSP 90-alpha", "aln": "MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPSKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEEKEEEKEKEEKESDDKPEIEDVGSDEEEEE----KKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITN-----------------------------------EEYGEFYKSLTNDWEEHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTE------------------------------------------------------------------------LAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLK------------------------------------------------------------------------DYCTRMKENQKHIYFITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEAD-KNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDD--PTVDDTSAAVTEEMPP-------------LEGDDDTSRMEEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZQP6-1", "uniprot_id": "A0A8I5ZQP6_RAT", "id": "A0A8I5ZQP6-1", "name": "", "aln": "----------------------------------------------------------------------------------WTRGRSCTLISFPTSKTEPSLLRN---------------------------------------------------------------------------------------------------------------------------VSDDEAEEKEEKEEEKEKEEKESDDKPEIEDVGSDEEEEE----KKDGDKKEKKKIKEKYIDQEELNKTKPIWTRNPDDITN-----------------------------------EEYGEFYKSLTNDWKEHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVQRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISHEMLQQSKILKVIRKNLVKKCLELFTE------------------------------------------------------------------------LAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSAFGDEMVSLK------------------------------------------------------------------------DYCTRMKENQKHIYFITGETKDQV-----------HGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSSCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEAD-KNDKSVKDLVILLYKTALLSSSFSLEDPQTHANRIYRMIKLGLGIDEDD--PTVDDTSAAVTEEMPP-------------LEGDDDISRMEEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P82995-1", "uniprot_id": "HS90A_RAT", "id": "P82995-1", "name": "Heat shock protein HSP 90-alpha", "aln": "MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEEKEEEKEKEEKESDDKPEIEDVGSDEEEEE----KKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITN-----------------------------------EEYGEFYKSLTNDWEEHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTE------------------------------------------------------------------------LAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLK------------------------------------------------------------------------DYCTRMKENQKHIYFITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEAD-KNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDD--PTVDDTSAAVTEEMPP-------------LEGDDDTSRMEEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P02829-1", "uniprot_id": "HSP82_YEAST", "id": "P02829-1", "name": "ATP-dependent molecular chaperone HSP82", "aln": "--------------MASETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTLDEVN---------------------------------------ERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLVVTKEVEKEVP-IPEEEKKDEEKKDEEKKDEDDKKPKLEEVDEEE--EKK----PKTKKVKEEVQEIEELNKTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNE------------------------------------------------------------------------IAEDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLT------------------------------------------------------------------------DYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITKD-FELEETDEEKAEREKEIKEYEPLTKALKEILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTKLLYETALLTSGFSLDEPTSFASRINRLISLGLNIDEDE--ETETAPEAST-AAP---------------VEEVPADTEMEEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P02828-1", "uniprot_id": "HSP83_DROME", "id": "P02828-1", "name": "Heat shock protein 83", "aln": "------------MPEEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADKVTVTSKNNDDEQYVWESSAGGSFTVRADNS----------------------------------------EPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKLLVEKEREKEV---SDDEADDEKKEGDEKKEMETDEPKIEDVGEDEDADKKDKDAKKKKTIKEKYTEDEELNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRTPFDLFENQKKRNNIKLYVRRVFIMDNCEDLIPEYLNFMKGVVDSEDLPLNISREMLQQNKVLKVIRKNLVKKTMELIEE------------------------------------------------------------------------LTEDKENYKKFYDQFSKNLKLGVHEDSNNRAKLADFLRFHTSASGDDFCSLA------------------------------------------------------------------------DYVSRMKDNQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVIQHLKEYKGKQLVSVTKEGLELPEDESEKKKREEDKAKFESLCKLMKSILDNKVEKVVVSNRLVDSPCCIVTSQFGWSANMERIMKAQALRDTATMGYMAGKKQLEINPDHPIVETLRQKADAD-KNDKAVKDLVILLFETSLLSSGFSLDSPQVHASRIYRMIKLGLGIDEDE--PMTTDDAQSAGDAPSL-------------VEDTEDASHMEEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q90474-1", "uniprot_id": "H90A1_DANRE", "id": "Q90474-1", "name": "Heat shock protein HSP 90-alpha 1", "aln": "---MPEKSAQPVMEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSCKDLKIELIPDQKERTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPDFG----------------------------------------ESIGRGTKVILHLKEDQSEYVEEKRIKEVVKKHSQFIGYPITLYIEKQREKEVD-LEEGEKQEEE---EVAAGEDKDKPKIEDLGADEDEDSKDGKNKRKKKVKEKYIDAQELNKTKPIWTRNPDDITNEEYGEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCEELIPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLDLFTE------------------------------------------------------------------------LAEDKDNYKKYYEQFSKNIKLGIHEDSQNRKKLSDLLRYYTSASGDEMVSLK------------------------------------------------------------------------DYVSRMKDTQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEYDGKNLVSVTKEGLELPEDEEEKKKQDELKAKYENLCKIMKDILDKKIEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKSQALRDNSTMGYMTAKKHLEINPAHPIVETLREKAEAD-KNDKAVKDLVILLFETALLSSGFTLDDPQTHANRIYRMIKLGLGIDDDD--SVVEEISQPAEEDMPV-------------LEGDDDTSRMEEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q58FG1-1", "uniprot_id": "HS904_HUMAN", "id": "Q58FG1-1", "name": "Putative heat shock protein HSP 90-alpha A4", "aln": "------------------------------------------------------------MESLTDPSKLDSGKEPHISLIPNKQDRTLTIVDTGIGMTKADLINNLGTITKSETKVFMEVLQAGADISMIGQFSVGFYSAYSVAEKVTVITKHNNDEQYAWESSLRGSFT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYREFYKSLTINWEDYLAVKHFSVEGQLEFRAFLFVPRLAPFELLETRKKKNKIKLSARRDLIMDNCEELIPEYLNFIRGVVDSEDLPLNIFR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ETKDQVANSTIVQRLWKHGLEVIYTIEPIDEYCVQQLKEFEGKTLVSVTKEDLELPEDEEEKKKQEEGKQKTK----------QKKNQSLRTS----------AKSTYGWTANMERIMKAQALRDNSTTGYMAAKKHLEINPDHSFIDTLRQKAETD-KNDKSVKDLVILLYETALLSSDFGLEGPQTHANRIYRMNKLGLGTDEDD--PTADDTSAAVTEEMPP-------------LEGDDDTSRMEK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GLF3-1", "uniprot_id": "A0A8I6GLF3_RAT", "id": "A0A8I6GLF3-1", "name": "", "aln": "-----MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKS----------------------------------------------------------------------------------------------------------------------EDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKE---ISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDES----------------------------------------------SKDKKKKTKTIKEKSID-QEEL----------------NKTKP---------IWTRNPDDITQEEYGEFYKSLTNAWEDHLA----------------------------------------------------------------------------------------------------------------------------------------------------MTSLS------------------------------------------------------------------------GYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEAD-TNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDE--VTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P34058-1", "uniprot_id": "HS90B_RAT", "id": "P34058-1", "name": "Heat shock protein HSP 90-beta", "aln": "-----MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHG----------------------------------------EPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKE---ISDDEAEEEKGEKEEEDKEDEEKPKIEDVGSDEEDDS----------------------------------------------GKDKKKKTKKIKEKYID-QEEL----------------NKTKP---------IWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLS------------------------------------------------------------------------EYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEAD-KNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDE--VTAEEPSAAVPDEIPP-------------LEGDEDASRMEEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08238-1", "uniprot_id": "HS90B_HUMAN", "id": "P08238-1", "name": "Heat shock protein HSP 90-beta", "aln": "-----MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHG----------------------------------------EPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKE---ISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLN------------------------------------------------------------------------------------------------------------------------------------------------ISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEAD-KNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDE--VAAEEPNAAVPDEIPP-------------LEGDEDASRMEEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58FF7-1", "uniprot_id": "H90B3_HUMAN", "id": "Q58FF7-1", "name": "Putative heat shock protein HSP 90-beta-3", "aln": "-----MPEEVHHGEEEVETFAFQAEIAQLISLIINTFYSNEEIFLQELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLALVDTGIGMTKADLINNLRTIAKSGTKACMEALQA---------------------EKLVVITKHNDDEQYAWESSAGGSFTVHADHG----------------------------------------EPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEQDKE---ISDDEAEEEKGEKEEEDKDDEEKPKIKDVGSDEEDDS-------------------------------------KEYGEFYKSLTSDWEDHLAVKHFSVEGQLEFRALLFSPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIHGVVDSEDLPLN------------------------------------------------------------------------------------------------------------------------------------------------ISREMLQQSKILK---------------------------------------------------------------------YVSHMKETQKSTYYITGESKEQVANSAFVERVRKQGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKEKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMEQIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKAEAD-KNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNHIYHMIKLGLGTDEDE--VAAEEPSDAVPDEIPP-------------LEGDEDASRMEEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11499-1", "uniprot_id": "HS90B_MOUSE", "id": "P11499-1", "name": "Heat shock protein HSP 90-beta", "aln": "-----MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHG----------------------------------------EPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKE---ISDDEAEEEKGEKEEEDKEDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLN------------------------------------------------------------------------------------------------------------------------------------------------ISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEAD-KNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDE--VTAEEPSAAVPDEIPP-------------LEGDEDASRMEEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q58FF6-1", "uniprot_id": "H90B4_HUMAN", "id": "Q58FF6-1", "name": "Putative heat shock protein HSP 90-beta 4", "aln": "-----------------------------MSLIINTFYSNKEIFLQELISNASDALDKIRYESLTDPSKLDGGKELKIDIIPNPRECILTLVNTGIGMTKADLINNLGAIAKSGTEAFMEAFQSCAEISMIGQFGVG-FYSAYLVAEKVAITKHNDEEQYSWVSSAGSSFTLHVDHG----------------------------------------EPIDRDTKVILHLKEDQTEYLEERWVKEVVKKHPQFIGCLIAVYLEKEPEKE---ISDD--EEEKGEKEEEDKDDKEKPKTEDVGSDEEDDT----------------------------------------------DKNNKKKTKKIKEKYTD-REEL----------------NQTKP---------IWTRNPDDITQEECGEFYKSLTSAWEDHLAVKQFPVEEQEENEQLCVHHVWIMDSFDDLMPEYVG-----------------------------------------------------------------FVREDKENNKKLDEVFSKISWLGIHEDSINWRHLSELLWSHTFQSGDEMTSLS------------------------------------------------------------------------EYVSCMKEAQKSICDIIGECKEQVANSAFVEQEWKKGFEVIYMSEPIDEYCVQQLKEFDGKSLLSVTKEGLELPEDEEEKKIMEESNVKFENLCRLMKEILDKKVERVTISSRLVSSPCRIVTSTYS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O57521-1", "uniprot_id": "HS90B_DANRE", "id": "O57521-1", "name": "Heat shock protein HSP 90-beta", "aln": "-----MPEEMRQ-EEEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELVSNASDALDKIRYESLTDPTKLDSGKDLKIDIIPNVQERTLTLIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVKVDHG----------------------------------------EPIGRGTKVILHLKEDQTEYIEEKRVKEVVKKHSQFIGYPITLYVEKERDKE---ISDDEAEEEKAEKEEKEEEGEDKPKIEDVGSDDEEDT----------------------------------------------KDKDKKKKKKIKEKYID-QEEL----------------NKTKP---------IWTRNPDDISNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFAELAEDKDNYKKFYDAFSKNLKLGIHEDSQNRKKLSELLRYQSSQSGDEMTSLT------------------------------------------------------------------------EYVSRMKENQKSIYYITGESKDQVAHSAFVERVCKRGFEVLYMTEPIDEYCVQQLKDFDGKSLVSVTKEGLELPEDEDEKKKMEEDKAKFENLCKLMKEILDKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKAEAD-KNDKAVKDLVILLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDEDEDVPVEEPSSAAAPEDIPP-------------LEGDDDASRMEEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07900-1", "uniprot_id": "HS90A_HUMAN", "id": "P07900-1", "name": "Heat shock protein HSP 90-alpha", "aln": "MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTG----------------------------------------EPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEK----------------------------------------------KDGDKKKKKKIKEKYID-QEEL----------------NKTKP---------IWTRNPDDITNEEYGEFYKSLTNDWEDHLA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q14568-1", "uniprot_id": "HS902_HUMAN", "id": "Q14568-1", "name": "Heat shock protein HSP 90-alpha A2", "aln": "MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIWYESLTDPSKLDSGKELHINLIPNKQDQTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVSFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTG----------------------------------------ERMGRGTKVILHLKEDQTEYLEEQRIKEIVKKHSQLIGYPITLFVEKECDKEVSDDETEEKEDKEEEKEKEEKESKDKPEIEDVGSDEEEEK----------------------------------------------KDGDKKKKK-TKEKYID-QEEL----------------NKTKP---------IWTRNPDDITNEEYGEFCKNLTNDWEDHLA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKHFSVEGQLEFRALLFVP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58FG0-1", "uniprot_id": "HS905_HUMAN", "id": "Q58FG0-1", "name": "Putative heat shock protein HSP 90-alpha A5", "aln": "------------------------------------------------------------------------------MGFHHVGQAGLELLTSGHPALER------------------------------------------------------------------------------------------------------------------------------------RPEYLEERRIKEIVKKHSQFIGYPITLFVEKKRNKQ----VSDAEAEKKEDKRKKKKESNDKPEIEDVGSDEEEEK-----------------------------------------------KDADKKKKKSKEKYIDQEL------------------NKTKP---------IWTRNPDAITNEEYGEFHQSLTNNWEDHLAVKHFSVEG-------------------------------------------------------------------------------------------------------------------------------------------QLEELK------------------------------------------------------------------------DSRRVMKANQKHIYYITGETKDQVANSAFVECLQKHGLEVIYMIELIDKYCVQQLKELESKTVVSVAKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDMLEKKVKKVVVSN---------------------------------------------------------------------------------------CMEDPQRHTNKIYRMIKLGLGVDEYD--PTANDINAAITKEMPP-------------LRGGDDTSRMEEVGGSG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :. *. : . .:.* : * .* :.:.. : * :..: . : . .: ", "identical_positions": 5, "similar_positions": 27, "identity": "0.45%" }, { "cls_id": "homologset.agr.SGD:S000006163", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCS4-1", "uniprot_id": "D3ZCS4_RAT", "id": "D3ZCS4-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------MESCTAGQARTAY------DRLTAEEMDEQRRQNVAYQYLCRLEEAKRWMEVCLKEELPSPVELEESLRNGVLLAKLGHCFAPSVVPLKKIYDMEQLRYQATGLHFRHTDNINFWLSAVAHIGLPSTFLPETTDIYDKKNMPRVIYCIHALSLFLFRLGLAPQIHDLYGKVKFTAEELSNIASELAKYGLQLPAFSKIGGILANEFSADEAAVHAAILAINDAVERGVVEDTLVALQNPNALLGNLREPLAAVYQELLALAKMEKAANARNH---DDGQDQDIYESCLTQAEIQGHINLANVQGALEVVDDALERQSPEALLEALRDPVLALQGVRQAFADWYLEQLTSDREQKSQELGLVRLLEKEEIQAGVAAANEKGDQEQAMLRAVWKINKAIQRGVAADTVKELMCPEAQLPQVYPFASAVYQQELALLQKQQQGE-LDQEELFVAVEMLSAVVLINRALEAGDACTFWDNLVNPATGLAQVEEENAQRYFDALVKVQ-QLRGTHRGFLSWNDLQAAVSQVNAQVQEETDQVLAISLINEALDQGCPEKTLSALLLPAAGLEDVSLPVAPRYHHLLVAAKRQKAQKTGDPGAVLWLEEIRQGVARANEDTNTAQRIALGVAAINQAIKEGKAAQTERVLRNPNVALRGIVPDCAKSYQQALEGAAAKKHRPGDT-AFWVPRDMKDGTAYYFHLQTFQGTWERPPSRHLNASHLTWEEIQSVITKVTAAHDRQLLWKANVGFVIKLQARLRGFLVRQKFAESSHFLRTLLPAVIKIQAHWRGYRQRKTYQERLQYFKANLNAIITIQAWARMWAARRQYLRRLRYFQKNVDSVVKIQAFFRARKARDDYRMLVHARHPPLSVVRKFAHLLNQSQEDFSAEAELLRLQEEVVRKIRSNQQLEQDLNLMDIKIGLLVKNRITLQEVVSHCKKLTKKNKEQLSDMMILDKQK-GLKSLSREKRQKLEAYQHLFYLLQTQPIYLAKLIFQMPQNKTTKFMEGVIFSLYNYASNRREAYLLLQLFRTALQEEIKSKVEQPQDVVTGNPTVVRLVVRFYRNGRGQSALQEILGKVIQDVLEDRSVSIHTDPVHIYKSWINQVEAQTGQRSHLPYDVTPEQALSHSEVQRRLDISLRNLLAMTEKFFVAISSSVDHIPYGIRYMAKVLKTTLETKFPNATERDIYKVVGNLLYYRFLNPAVVAPDAFDIVAMAAGSSLAAPQRHALGAVAQLLQHAAAGKVFSGESRHLRILNGYLEDLHHKFRKFICRACRVPEPEERFAIDEYSDMVAVAKPMVYITVGELIGTHRLLLEHQDQLAPGHQDPLHQLLEDLGEPPTITD-----LIGDHVATDGH-------EDLSRLEVSLTLTNKFEGLETDADHNSTQSLLLSTKQMLADLIQFHPGDSLEEILTSSAPREHEEAHHRLMCWRQACDTQKPEPLQRRHSLMAHSLLPLAEKQQRVLRNLRRLQGLGLVRANDCYQGLVDELAKDICNQRRHRQRRKAEMLRLRATLQGLDAKTIFYEEQGDYYNQYTQACLDHLAPNP---------RSSGKGKKQPS-LHYTAAQLLEKGVLVEIEDLPVSHFRNVIFDITPGDEAGRFAVNAKFLGVDMEKFQLHYQDLLQLQYEGVAVMKLFNKAKVNVNLLIFLLNKKFLRK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F8VQ29-1", "uniprot_id": "F8VQ29_MOUSE", "id": "F8VQ29-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------MEPCAAGRARTAY------ERLTAEEMDEQRRQNVAYQYLCRLEEAKRWMEVCLKEELPSPVELEESLRNGVLLAKLGHCFAPSVVPLKKIYDVEQLRYQATGLHFRHTDNINFWLSAVAHIGLPSIFLPETTDIYDKKNMPRVIYCIHALSLFLFRLGLAPQIHDLYGKVKFTAEELGNIASELAKYGLQLPAFSKIGGILANEFSADEAAVHAAILAINDAVERGVVEDTLVTLQNPNALLGNLREPLAAVYQELLALAKMEKAANARNH---DDGQEQDIYESCLTQAEIQGHINLANVQGALEVVDDALERQNPGALLEALHDPVLALQGVRGTFADWYLEQLTSDREQKSQELGLVRLLEKEEIQAGVAVANEKGDEEQTMLQAVWRINKAIRRGVAADTVKELMCPEAQLPRVYPFASAFYQQELALLQKQQQGE-LGQEELFVAVEMLSAVVLINRALEAGDVCAFWDNLVNPATGLAQVEEENAQRYFDALVKVQ-QFQGTHRGILSWNDLQAAVSQVNEQVQEETDQVLAISLINEALDQGCPEKTLSALLLPAAGLEDVSLHVAPRYHLLLVAAKRQKARVTGDPGAVLWLEEIRQGVARANEDTSTAQRIALGVAAINQAIKEGKAAQTERVLRNPNVALRGIVPDCAKSYQQALEGAAAKKQCPGDT-AFWVQHDMKDGTAYYLHLQTFQGTWEHPSGCHLNTSHLTWEEIQSVITKVTAAHDRQLLWKANVGFVIKLQARLRGFLVRQKFAESSHVFRTLLPAVIKIQAHWRGYRQRKAYQERLQHFKANLDAIIKIQAWARMWAARRRYLRRLRYFQKNVDSVVKIQAFFRARKARDDYRMLVHARHPPLCVVRKFAHLLNQSQEDFSAESELLKLQEEVVRKIRSNQQLEQDLNLMDIKIGLLVKNRITLQEVVSHCKKLTKKNKEQLSDMMILDKQK-GLKSLSREKRQKLEAYQHLFYLLQTQPIYLAKLIFQMPQNKTTKFMEGVIFSLYNYASNRREAYLLLQLFRTALQEEIKSKVEQPQDVVTGNPTVVRLVVRFYRNGRGQSALQEILGKVIQDVLEDRSVSIHTDPVHIYKSWINQEEAQTGQRSHLPYDVTPEQALSHSEVQRRLDISLRSLLTLTEKFFVAISSSVDHIPYGMRYMAKVLKTTLEKKFPNATERDIYKVVGNLLYYRFLNPAVVAPDAFDIVAMAAGSTLAAPQRHALGAVAQLLQHAAAGQIFSGESRHLRVLNDYLEDLHLKFRKFICRACRVPEPEERFAIDEYSDMVAVAKPMVYITVGELIGTHRLLLEHQDQLAPGHQDPLHQLLEDLGEPPTISD-----LIGDNIATDGH-------VDLSRLEVSLTLTNKFEGLETDADHNSNQSLLLSTKQMLADLIQFHPGESLEEILTSSAPREHEEAHRRLMCWRQACDTQKPEPLRRHHSLMAHSLLSLSEKQQRVLRNLRRLQGLGLVRASDCYQGLVDELAKDICNQRRHRQRRKAEMLRLRTTLQGLDAKTIFYEEQGDYYNQYIQACLDHLAPKP---------KSSGKGKKQPS-LHYTAAQLLEKGVLVEIEDLPVSHFRNVIFDITPGDEAGRFFVNAKFLGVDMEKFQLHYQDLLQLQYEGVAVMKLFNKAKVNVNLLIFLLNKKFLRK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86VI3-1", "uniprot_id": "IQGA3_HUMAN", "id": "Q86VI3-1", "name": "Ras GTPase-activating-like protein IQGAP3", "aln": "---------------------------------------------------------------------------------------------------------------------------MERRAAGPGWAAY------ERLTAEEMDEQRRQNVAYQYLCRLEEAKRWMEACLKEELPSPVELEESLRNGVLLAKLGHCFAPSVVPLKKIYDVEQLRYQATGLHFRHTDNINFWLSAIAHIGLPSTFFPETTDIYDKKNMPRVVYCIHALSLFLFRLGLAPQIHDLYGKVKFTAEELSNMASELAKYGLQLPAFSKIGGILANELSVDEAAVHAAVLAINEAVERGVVEDTLAALQNPSALLENLREPLAAVYQEMLAQAKMEKAANARNH---DDRESQDIYDHYLTQAEIQGNINHVNVHGALEVVDDALERQSPEALLKALQDPALALRGVRRDFADWYLEQLNSDREQKAQELGLVELLEKEEVQAGVAAANTKGDQEQAMLHAVQRINKAIRRRVAADTVKELMCPEAQLPPVYPVASSMYQLELAVLQ-QQQGE-LGQEELFVAVEMLSAVVLINRALEARDASGFWSSLVNPATGLAEVEGENAQRYFDALLKLR-QERGMGEDFLSWNDLQATVSQVNAQTQEETDRVLAVSLINEALDKGSPEKTLSALLLPAAGLDDVSLPVAPRYHLLLVAAKRQKAQVTGDPGAVLWLEEIRQGVVRANQDTNTAQRMALGVAAINQAIKEGKAAQTERVLRNPAVALRGVVPDCANGYQRALESAMAKKQRPADT-AFWVQHDMKDGTAYYFHLQTFQGIWEQPPGCPLNTSHLTREEIQSAVTKVTAAYDRQQLWKANVGFVIQLQARLRGFLVRQKFAEHSHFLRTWLPAVIKIQAHWRGYRQRKIYLEWLQYFKANLDAIIKIQAWARMWAARRQYLRRLHYFQKNVNSIVKIQAFFRARKAQDDYRILVHAPHPPLSVVRRFAHLLNQSQQDFLAEAELLKLQEEVVRKIRSNQQLEQDLNIMDIKIGLLVKNRITLQEVVSHCKKLTKRNKEQLSDMMVLDKQK-GLKSLSKEKRQKLEAYQHLFYLLQTQPIYLAKLIFQMPQNKTTKFMEAVIFSLYNYASSRREAYLLLQLFKTALQEEIKSKVEQPQDVVTGNPTVVRLVVRFYRNGRGQSALQEILGKVIQDVLEDKVLSVHTDPVHLYKNWINQTEAQTGQRSHLPYDVTPEQALSHPEVQRRLDIALRNLLAMTDKFLLAITSSVDQIPYGMRYVAKVLKATLAEKFPDATDSEVYKVVGNLLYYRFLNPAVVAPDAFDIVAMAAGGALAAPQRHALGAVAQLLQHAAAGKAFSGQSQHLRVLNDYLEETHLKFRKFIHRACQVPEPEERFAVDEYSDMVAVAKPMVYITVGELVNTHRLLLEHQDCIAPDHQDPLHELLEDLGELPTIPD-----LIGESIAADGH-------TDLSKLEVSLTLTNKFEGLEADADDSNTRSLLLSTKQLLADIIQFHPGDTLKEILSLSASREQEAAHKQLMSRRQACTAQTPEPLRRHRSLTAHSLLPLAEKQRRVLRNLRRLEALGLVSARNGYQGLVDELAKDIRNQHRHRHRRKAELVKLQATLQGLSTKTTFYEEQGDYYSQYIRACLDHLAPDS---------KSSGKGKKQPS-LHYTAAQLLEKGVLVEIEDLPASHFRNVIFDITPGDEAGKFEVNAKFLGVDMERFQLHYQDLLQLQYEGVAVMKLFNKAKVNVNLLIFLLNKKFLRK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JKF1-1", "uniprot_id": "IQGA1_MOUSE", "id": "Q9JKF1-1", "name": "Ras GTPase-activating-like protein IQGAP1", "aln": "-----------------------------------------------------------------------------------------------------------------------MSAAEEVDGLGVVRPHYGSVLDNERLTAEEMDERRRQNVAYEYLCHLEEAKRWMEACLGEDLPPTTELEEGLRNGVYLAKLGNFFSPKVVSLKKIYDREQTRYKATGLHFRHTDNVIQWLNAMDEIGLPKIFYPETTDIYDRKNMPRCIYCIHALSLYLFKLGLAPQIQDLYGKVDFTEEEINNMKIELEKYGIQMPAFSKIGGILANELSVDEAALHAAVIAINEAIDRRVAADTFTALKNPNAMLVNLEEGLAPTYQDVLYQAKQDKMTNAKNR-TENSDRERDVYEELLTQAEIQGNVNKVNTSSALANISLALEQGCAVTLLKALQSLALGLRGLQTQNSDWYMKQLQSDLQQKRQ-SGQTDPLQKEEVQAGVDAANSAAQQYQRRLAAVAAINAAIQKGIAEKTVLELMNPEAQLPQVYPFAADLYQKELATLQQQSPEHSLTHPELTVAVEMLSSVALINRALESGDMTTVWKQLSSSVTGLTNIEEENCQRYLDELMKLKAQAHAENNAFITWNDIQACVDHVNLVVHEEHERILAIGLINEALDEGDAQKTLQALQIPAAKLEGVLAEVAQHYQDTLIRAKREKAQETQDESAVLWLDEIQGGIWQSNKDTQEAQRFALGISAINEAVDSGDVGRTLSALRSPDVGLYGVIPECGETYQSDLAEAKKKRLAAGDNNSKWVKHWVKGGYHYYHNLETQAGGWAEPPDFVQNSVQLSREEIQSSISGVTAAYNREQLWLANEGLITKLQACCRGYLVRQEFRSRMNFLKKQIPAITCIQSQWRGYKQKKAYQDRLAYLHSHKDEVVKIQSLARMHQARKRYRDRLQYFRDHINDIIKIQAFIRANKARDDYKTLINAEDPPMIVVRKFVHLLDQSDQDFQEELDLMKMREEVITLIRSNQQLENDLNLMDIKIGLLVKNKITLQDVVSHSKKLTKKNKEQLSDMMMINKQKGGLKALSKEKREKLEAYQHLFYLLQTNPTYLAKLIFQMPQNKSTKFMDSVIFTLYNYASNQREEYLLLRLFQTALQEEIKSKVDQIQEIVTGNPTVIKMVVSFNRGARGQNALRQILAPVVKEIMDDKSLNIKTDPVDIYKSWVNQMESQTGEASKLPYDVTPEQALSHEEVKTRLDNSIRNMRAVTDKFLSAIVSSVDKIPYGMRFIAKVLKDSLHEKFPDAGEDELLKIIGNLLYYRYMNPAIVAPDAFDIIDLSAGGQLTTDQRRNLGSIAKMLQHAASNKMFLGDNAHLSIINEYLSQSYQKFRRFFQVACDVPELQDKFNVDEYSDLVTLTKPVIYISIGEIINTHTLLLDHQDAIAPEHNDPIHELLDDLGEVPTIES-----LIGESCGNSNDPNKE----ALAKTEVSLTLTNKFDVPGDENAEMDARTILLNTKRLIVDVIRFQPGETLTEILETPATNEQEAEHQRAMQRRAIRDAKTPDKMKKSKPMKEDNNLSLQEKKEKIQTGLKKLTELGTVDPKNRYQELINDIAKDIRNQRRYRQRRKAELVKLQQTYSALNSKATFYGEQVDYYKSYIKTCLDNLASKG--KVSKKPREMKGKKSKKIS-LKYTAARLHEKGVLLEIEDLQANQFKNVIFEIGPTEEVGDFEVKAKFMGVQMETFMLHYQDLLQLQYEGVAVMKLFDRAKVNVNLLIFLLNKKFYGK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AJK7-1", "uniprot_id": "A0A8I6AJK7_RAT", "id": "A0A8I6AJK7-1", "name": "Ras GTPase-activating-like protein IQGAP1", "aln": "MARGGALRTATARALGRSCCCYGRPRLQGLCSSSPETGTRPPCPPRRRSMAWVWSGRTMAVSTGYLGVRGRGFPRGSAERVRGVAWDRTDPEEQPAVWLVARLASEPSRAPEAAGRNLEASAFARRRGRGAPPRASTAVLDNERLTAEEMDERRRQNVAYEYLCHLEEAKRWMEACLGEDLPPTTELEEGLRNGVYLAKLGNFFSPKVVSLKKIYDREQTRYKATGLHFRHTDNVIQWLNAMDEIGLPKIFYPETTDIYDRKNMPRCIYCIHALSLYLFKLGLAPQIQDLYGKVDFTEEEINNMKIELEKYGIQMPAFSKIGGILANELSVDEAALHAAVIAINEAIDHRVAADTFTALKNPNAMLVNLEEALAPTYQDVLYQAKQDKMTNAKNR-TENSDRERDVYEELLTQAEIQGNVNKVNTSSALANINLALEQGCALTLLKALQSVALGLRGLQTQNSDWYLKQLQSDLQQKRQ-SGQTDPLQKEEVQAGVDAANGAAQQYQRRLAAVAAINAAIQKGIAEKTVLELMNPEAQLPQVYPFAADLYQKELATLQQQSPEHSLTHPELTVAVEMLSSVALINRALESGDMNTVWKQLSSSVTGLTNIEEENCQRYLDELMKLKAQAHAENNEFVTWNDIQACVDHVNLVVHEEHERILAIGLINEALDEGDAQKTLQALQIPAAKLEGVLPEVAQHYQDTLIRAKREKAQETQDESAVLWLDEIQGGIWQSNKDTQEAQRFALGIFAINEAVESGDVGRTLSALRSPDVGLYGVIPECGETYQSDLAEAKKKRLAAGDNNSKWVKHWVKGGYHYYHNLETQAGGWAEPPDFVQNSVQLSREEIQSSISGVTAAYNREQLWLANEGLITKLQACCRGYLVRQEFRSRMNFLKKQIPAITCIQSQWRGYKQKKAYQDRLAYLHSHKDEVVKIQSLARMHQARKRYRDRLQYFRDHINDIIKIQAFIRANKARDDYKTLINAEDPPMIVVRKFVHLLDQSDQDFQEELDLMKMREEVITLIRSNQQLENDLNLMDIKIGLLVKNKITLQDVVSHSKKLTKKNKEQLSDMMMINKQKGGLKALSKEKREKLEAYQHLFYLLQTNPTYLAKLIFQMPQNKSTKFMDSVIFTLYNYASNQREEYLLLRLFQTALQEEIKSKVDQIQEIVTGNPTVIKMVVSFNRGARGQNALRQILAPVVKEIMDDKSLNIKTDPVDIYKSWVNQMESQTGEASKLPYDVTPEQALSHEEVKTRLDNSIRNMRAVTDKFLSAIVSSVDKIPYGMRFIAKVLKDSLHEKFPDAAEDELLKIIGNLLYYRYMNPAIVAPDAFDIIDLSAGGQLTTDQRRNLGSIAKMLQHAASNKMFLGDNAHLSIINEYLSQSYQKFRRFFQAACDVPELQDKFNVDEYSDLVTLTKPVIYISIGEIINTHTLLLDHQDAIAPEHNDPIHELLDDLGEVPTIES-----LIGESCGNSNDPSKE----ALAKTEVSLTLTNKFDVPGDENAEMDARTILLNTKRLIVDVIRFQPGETLTEILETPATNEQEAEHQRAMQRRAIRDAKTPDKMKKSKPMKEDNNLSLQEKKEKIQTGLKKLTELGTVDPKNRYQELINDIAKDIRNQRRYRQRRKAELVKLQQTYSALNSKATFYGEQVDYYKSYIKTCLDNLASKG--KVSKKPREMKGKKSKKIS-LKYTAARLHEKGVLLEIEDLQANQFKNVIFEIGPTEEVGDFEVKAKFMGVQMETFMLHYQDLLQLQYEGVAVMKLFDRAKVNVNLLIFLLNKKFYGK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P46940-1", "uniprot_id": "IQGA1_HUMAN", "id": "P46940-1", "name": "Ras GTPase-activating-like protein IQGAP1", "aln": "-----------------------------------------------------------------------------------------------------------------------MSAADEVDGLGVARPHYGSVLDNERLTAEEMDERRRQNVAYEYLCHLEEAKRWMEACLGEDLPPTTELEEGLRNGVYLAKLGNFFSPKVVSLKKIYDREQTRYKATGLHFRHTDNVIQWLNAMDEIGLPKIFYPETTDIYDRKNMPRCIYCIHALSLYLFKLGLAPQIQDLYGKVDFTEEEINNMKTELEKYGIQMPAFSKIGGILANELSVDEAALHAAVIAINEAIDRRIPADTFAALKNPNAMLVNLEEPLASTYQDILYQAKQDKMTNAKNR-TENSERERDVYEELLTQAEIQGNINKVNTFSALANIDLALEQGDALALFRALQSPALGLRGLQQQNSDWYLKQLLSDKQQKRQ-SGQTDPLQKEELQSGVDAANSAAQQYQRRLAAVALINAAIQKGVAEKTVLELMNPEAQLPQVYPFAADLYQKELATLQRQSPEHNLTHPELSVAVEMLSSVALINRALESGDVNTVWKQLSSSVTGLTNIEEENCQRYLDELMKLKAQAHAENNEFITWNDIQACVDHVNLVVQEEHERILAIGLINEALDEGDAQKTLQALQIPAAKLEGVLAEVAQHYQDTLIRAKREKAQEIQDESAVLWLDEIQGGIWQSNKDTQEAQKFALGIFAINEAVESGDVGKTLSALRSPDVGLYGVIPECGETYHSDLAEAKKKKLAVGDNNSKWVKHWVKGGYYYYHNLETQEGGWDEPPNFVQNSMQLSREEIQSSISGVTAAYNREQLWLANEGLITRLQARCRGYLVRQEFRSRMNFLKKQIPAITCIQSQWRGYKQKKAYQDRLAYLRSHKDEVVKIQSLARMHQARKRYRDRLQYFRDHINDIIKIQAFIRANKARDDYKTLINAEDPPMVVVRKFVHLLDQSDQDFQEELDLMKMREEVITLIRSNQQLENDLNLMDIKIGLLVKNKITLQDVVSHSKKLTKKNKEQLSDMMMINKQKGGLKALSKEKREKLEAYQHLFYLLQTNPTYLAKLIFQMPQNKSTKFMDSVIFTLYNYASNQREEYLLLRLFKTALQEEIKSKVDQIQEIVTGNPTVIKMVVSFNRGARGQNALRQILAPVVKEIMDDKSLNIKTDPVDIYKSWVNQMESQTGEASKLPYDVTPEQALAHEEVKTRLDSSIRNMRAVTDKFLSAIVSSVDKIPYGMRFIAKVLKDSLHEKFPDAGEDELLKIIGNLLYYRYMNPAIVAPDAFDIIDLSAGGQLTTDQRRNLGSIAKMLQHAASNKMFLGDNAHLSIINEYLSQSYQKFRRFFQTACDVPELQDKFNVDEYSDLVTLTKPVIYISIGEIINTHTLLLDHQDAIAPEHNDPIHELLDDLGEVPTIES-----LIGESSGNLNDPNKE----ALAKTEVSLTLTNKFDVPGDENAEMDARTILLNTKRLIVDVIRFQPGETLTEILETPATSEQEAEHQRAMQRRAIRDAKTPDKMKKSKSVKEDSNLTLQEKKEKIQTGLKKLTELGTVDPKNKYQELINDIARDIRNQRRYRQRRKAELVKLQQTYAALNSKATFYGEQVDYYKSYIKTCLDNLASKG--KVSKKPREMKGKKSKKIS-LKYTAARLHEKGVLLEIEDLQVNQFKNVIFEISPTEEVGDFEVKAKFMGVQMETFMLHYQDLLQLQYEGVAVMKLFDRAKVNVNLLIFLLNKKFYGK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UQ44-1", "uniprot_id": "IQGA2_MOUSE", "id": "Q3UQ44-1", "name": "Ras GTPase-activating-like protein IQGAP2", "aln": "--------------------------------------------------------------------------------------------------------------------------MPHEELPSLQRPRYGSIVDDERLSAEEMDERRRQNIAYEYLCHLEEAKRWMEVCLVEELPPTTELEEGLRNGVYLAKLAKFFAPKMVSEKKIYDVEQTRYKKSGLHFRHTDNTVQWLRAMEAIGLPKIFYPETTDVYDRKNIPRMIYCIHALSLYLFKLGIAPQIQDLLGKVDFTEEEISNMRKELEKYGIQMPAFSKIGGILANELSVDEAALHAAVIAINEAIEKGVAKQTIITLRNPNAVLTCVDDSLSQEYQKELWEAKKKKEESAKLKNSCISEEERDAYEELLTQAEIQSNISTVN------------------------------------------------------------------------------------RMAAVDHINAVLQEGDPENTLLALKKPEAQLPAVYPFAAVMYQNELFNLQKQNTSNYLAHEELLIAVEMLSAVALLNQALESSDLVAVQNQLRSPTIGFNNLDEAHVDRYADALLSVKQEALSQGQDTLSWNEIQNCIDMINNQIQEENDRMVVLGYINEAIDAGNPLKTLDTLLLPTANIRDVDPDCAQHYQDVLFYTKSQKLGDPKNVSKVLWLDEIQQAINEANVDENRAKQWVTLVVDVNECLDRKQSDHILTALKSSPSNIHNILPECANKYYDTLVKAKESKTDNESSEGSWVTLNVQEKYNYYYNTDSKEGSWVPPELCLSKESWLTGEEIEDIVEEVTSDYIREKLWSASEDLLVRFEATTLGPALREEFEARKAFLYEQTESVVKIQAFWKGFKQRQEYLHRQQVFAGNVDSVVKIQSWFRMVTARKSYLSRLRYFEDHKNEIVKIQSLLRASKARDDYKALVGSENPPLTVIRKFVYLLDQSDLDFQEELEVARLREEVVTKIRANQQLEKDLNLMDIKIGLLVKNRITLEDVISHRKKLNKKKGGEIEILNNTDNK--GIKSLSKERRKTLETYQQLFYLLQTKPSYLAKLIFQMPQNKSTKFMDTVIFTLYNYASNQREEYLLLKLFKTALEEEIKSKVDQVQDIVTGNPTVIKMVVSFNRGARGQNTLRQLLAPVVKEIIEDKALVINTNPVEVYKAWVNQLETQTGEASKLPYDVTTEQALTYPEVKNKLEASIENLRKVTDKVLGSIISSLDLLPYGLRYIAKVLKNSIREKFPDATEEELLKIVGNLLYYRYMNPAIVAPDGFDIIDMTAGGQINSNQRRNLGSVAKVLQHAASNKLFEGENEHLSSMNNYLSETYQEFRKYFQEACDVPEPEEKFNMDKYTDLVTVSKPVIYISIEEIINTHLLLLEHQDAIATEKSDLLNELLESLGEVPTVES-----FLGEGAVDPNDPNKENTLNQLSKTEISLSLTSKYDVKDGE--AVDGRSLMIKTKKLIIDVTRNQPGSTLTEILETPATGQQELEHAKDMESRAVVDSRTPEEGKQSQAVIEDARLPLEQKKRKIQRNLRTLEQTGHVSSKNKYQDILNEIAKDIRNQRIHRKLRKAELSKLQQTLNALNKKAAFYEDQINYYDTYIKTCVDNLKRKNSRRSIKLDGKAEPKGTKRVKPVRYTAAKLHDKGVLLGIDDLQTNQFKNVMFDIIATEDMGIFDVRSKFLGVEMEKVQLNIQDLLQMQYEGVAVMKMFDKVKVNVNLLIYLLNKKFYGK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AM38-1", "uniprot_id": "A0A8I6AM38_RAT", "id": "A0A8I6AM38-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------MPHEELPSLQRPRYGSIVDDERLSAEEMDERRRQNIAYEYLCHLEEAKRWMEVCLVEELPPTTELEEGLRNGVYLAKLAKFFAPKVVSEKKIYDVEQSRYKKSGLHFRHTDNTVQWLRAMEAIGLPKIFYPETTDVYDRKNIPRMIYCIHALSLYLFKLGIAPQIQDLLGKVDFTEEEISNMRKELEKYGIQMPAFSKIGGILASELSVDEAALHAAVIAINEAIEKGVAKQTIITLRNPNAVLTCVDDSLSQEYQKELWEAKKKKEETAKLKNSCISEEERDAYEELLTQAEIQSNIHAVN------------------------------------------------------------------------------------RMAAVDHINAVLREGDPENTLLALKKPEAQLPAVYPFAAAMYQNELFNLQKQNTSNYLAHEELLIAVEMLSAVALLNQALESNDLVAVQNQLRSPTIGFNNLDEAHVDRYADALLSVKQEALSQGQDTLSWNEIQNCIDMINNQIQEENERMVVLGYINEAIDEGNPLKTLDTLLLPTANIRGVDPDCAHHYQDVLFHTKSQKLRDPKNVSKVLWLDEIQQAINEANVDKNRAKQWVTLVVGVNECLDRKQSDDILTVLKSSSSNVHNILPECANKYFDTLMKAKESKTDGEPTEGPWVKLDVQQKYNYYYNTDSKEGSWIPPESCLCKESWLTGEEIEDIVEKVTSDYIRENLWSASEDLLLRFEATNSGPILREEFEARKAFLYKQVGNVVKIQAFWKGYKQRQEYLHRQQVFARNVDSVVKIQSWFRMVTARKSYLSRLQYFEDHENEIVKIQSLLRASKARDDYKALVGSENPPLTVIRKFVYLLDQSDLDFQEELEVARLREEVVTKIRANQQLEKDLNLMDIKIGLLVKNRITLEDVISHSKKLNKKKGGEIEILTNTDNQ--GIKSLSKERRKTLETYQQLFYLLQTKPSYLAKLIFQMPQNKSTKFMDTVIFTLYNYASNQREEYLLLKLFKTALEEEIKSKVDQVQDIVTGNPTVIKMVVSFNRGARGQNSLRQLLAPVVKEIIEDKALIINTNPVEVYKAWVNQLETQTGEASKLPYDVTTEQALTYPEVKNKLEASIENLRKVTDKVLSSIISSLDLLPYGLRYIAKVLKNSIREKFPDATEEELLKIVGNLLYYRYMNPAIVAPDGFDIIDMTAGGQINSNQRRNLGSVAKVLQHAASNKLFEGENEHLSSMNNYLSETYQEFRKYFQEACDVHEPEEKFNMDKYTDLVTVSKPVIYISIEEIINTHLLLLEHQDAIATEESDLLNELLESLGEVPTVES-----FLGEGAVDPNDPNKENTLNQLSKTEISLSLTSKYDVKDGE--AIDGRSLMIKTKKLIIDVVRNQPGSTLMEILETPATEQQELEHTKDMESRAVADSRALEEGKQSQAVIEDASLPLEQKKRKIQRNLRTLEQTGHVSSKNKYQDILNEIAKDIRNQRIHRKLRKAELSKLQQTLNALNKKAAFYEDQINYYDTYIKTCVDNLKRKNSRRSIKLDGKAEPKGTKRVKPVRYTAAKLHDKGVLLGIDDLQTNQFKNVMFDIIATEDMGIFDVRSKFLGVEMEKVQLNIQDLLQMQYEGVAVMKMFDKVKVNVNLLIYLLNKKFYGK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13576-1", "uniprot_id": "IQGA2_HUMAN", "id": "Q13576-1", "name": "Ras GTPase-activating-like protein IQGAP2", "aln": "--------------------------------------------------------------------------------------------------------------------------MPHEELPSLQRPRYGSIVDDERLSAEEMDERRRQNIAYEYLCHLEEAKRWMEVCLVEELPPTTELEEGLRNGVYLAKLAKFFAPKMVSEKKIYDVEQTRYKKSGLHFRHTDNTVQWLRAMESIGLPKIFYPETTDVYDRKNIPRMIYCIHALSLYLFKLGIAPQIQDLLGKVDFTEEEISNMRKELEKYGIQMPSFSKIGGILANELSVDEAALHAAVIAINEAVEKGIAEQTVVTLRNPNAVLTLVDDNLAPEYQKELWDAKKKKEENARLKNSCISEEERDAYEELLTQAEIQGNINKVN------------------------------------------------------------------------------------RQAAVDHINAVIPEGDPENTLLALKKPEAQLPAVYPFAAAMYQNELFNLQKQNTMNYLAHEELLIAVEMLSAVALLNQALESNDLVSVQNQLRSPAIGLNNLDKAYVERYANTLLSVKLEVLSQGQDNLSWNEIQNCIDMVNAQIQEENDRVVAVGYINEAIDEGNPLRTLETLLLPTANISDVDPAHAQHYQDVLYHAKSQKLGDSESVSKVLWLDEIQQAVDDANVDKDRAKQWVTLVVDVNQCLEGKKSSDILSVLKSSTSNANDIIPECADKYYDALVKAKELKSERVSSDGSWLKLNLHKKYDYYYNTDSKESSWVTPESCLYKESWLTGKEIEDIIEEVTVGYIRENIWSASEELLLRFQATSSGPILREEFEARKSFLHEQEENVVKIQAFWKGYKQRKEYMHRRQTFIDNTDSIVKIQSWFRMATARKSYLSRLQYFRDHNNEIVKIQSLLRANKARDDYKTLVGSENPPLTVIRKFVYLLDQSDLDFQEELEVARLREEVVTKIRANQQLEKDLNLMDIKIGLLVKNRITLEDVISHSKKLNKKKGGEMEILNNTDNQ--GIKSLSKERRKTLETYQQLFYLLQTNPLYLAKLIFQMPQNKSTKFMDTVIFTLYNYASNQREEYLLLKLFKTALEEEIKSKVDQVQDIVTGNPTVIKMVVSFNRGARGQNTLRQLLAPVVKEIIDDKSLIINTNPVEVYKAWVNQLETQTGEASKLPYDVTTEQALTYPEVKNKLEASIENLRRVTDKVLNSIISSLDLLPYGLRYIAKVLKNSIHEKFPDATEDELLKIVGNLLYYRYMNPAIVAPDGFDIIDMTAGGQINSDQRRNLGSVAKVLQHAASNKLFEGENEHLSSMNNYLSETYQEFRKYFKEACNVPEPEEKFNMDKYTDLVTVSKPVIYISIEEIISTHSLLLEHQDAIAPEKNDLLSELLGSLGEVPTVES-----FLGEGAVDPNDPNKANTLSQLSKTEISLVLTSKYDIEDGE--AIDSRSLMIKTKKLIIDVIRNQPGNTLTEILETPATAQQEVDHATDMVSRAMIDSRTPEEMKHSQSMIEDAQLPLEQKKRKIQRNLRTLEQTGHVSSENKYQDILNEIAKDIRNQRIYRKLRKAELAKLQQTLNALNKKAAFYEEQINYYDTYIKTCLDNLKRKNTRRSIKLDGKGEPKGAKRAKPVKYTAAKLHEKGVLLDIDDLQTNQFKNVTFDIIATEDVGIFDVRSKFLGVEMEKVQLNIQDLLQMQYEGVAVMKMFDKVKVNVNLLIYLLNKKFYGK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12280-1", "uniprot_id": "IQG1_YEAST", "id": "Q12280-1", "name": "Ras GTPase-activating-like protein IQG1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MTAYSGSPSKPGNNNSYLNRYVENLGTNVTPPLRPQSSSKINSSLNIASPSHLKTKTSASNSSATILSKKVESSVSKLKPS-LPNKLVGKYTVDLSNYSKIELR--YYEFLCRVSEVKIWIEAVIEEALPSEIELCVGDSLRNGVFLAKLTQRINPDLTTVIFPAGDKLQFKHTQNINAFFG--LVEHVGVPDSFRFELQDLYNKKNIPQVFETLHILISMINKKWPGKTPALTNVSGQISFTKEEIAACKKAWPRIRDFKSLGTNINTAPASPEEPKEK------------------------------------------------------------------------------------RSGLIKDFNKFERPNIPVEEILITPRKNITDANCSDFSNTPSPYNEAPKMSNLDVVVEKRKFTPIEPSLLGPTPSLEYSPIKNKSLSYYSPTISKYLTYDTEFYTRRSRAREEDLNYYQTFKYSPSHYSPMRRERMTEEQFLEKVVQLQN---ICRGVNTRFNLYIQKRLLNLFEQDILRFQACLRGNKFRVLSSMYLPIRRAKIDVPHVEAIQSRIKGSRIRYKYDKLKFTLSRFSCTVELLQAYCRSKLLKTTVNTKLNDIEISHYPLTKLQSYMRASYVRKKVMSLNTKLNDERESIMKFSAIIRGNVVRCSEDAILSAVHDVHKENISKLQSLIRGIFTRSCLASIIYSLGKENCN-IIQLSACIRGNAVRHKVQSLFAPENNLSETVHDLQGLVRGILVR--YTLDLVDDIVEYNNLALFQAFSRGALVRESLDQKSSFYKRNVRSVIMIQSWIRKSLQRSAYLELLDCPNPSLWAVKKFVHLLNG-----------TATIEEVQNQLESCQASLDSENMKKERLLKSIRQQLNINGVLDKFGLLKDKDHELG-------------ISDSTIPKSKYQKYEKLFYMLQVDPSYWKLLYLKEPEFVAKNVY--MTFGTVNQRMNDRERSYFTRFVCEMLQNAIN-EAPSIESFLDNRSQFWQTILQDFLRRESPEFFSIIVP--VLDYLSDPVVDFESDPYKIYQEIHGFSSPQHCS------------PVDDASTKNKFIDNLRCLWHAIEMVAEIYTRKVHTIPVEIRYLCTKIFCYAADKN--IEEIDSLRAISSILVNVFVSEYLVNREYYGYKDSNVQ-----KNNQKIDILMKSLATVFEIKNFDG---FLDPLNQYANEIKPHIKDVLYNVLVDPEYEQEGDRLIYLDMVSPS-PKLELLTEKVLEISGKFEEYLNEFP--EADILHDILEKNLDNSSFPRSGRVTLELDASAYRFLVSDDKMRKIYDQVKRAFVYMMQIEDVDTNLYDLSISTILPQDEPNFANFLEQNPKIRDDPMIQKLKPLKYFTLKNVTLKKIHELESTGTFCSSDNKLQNFLNDIANTIKNPNYAIDYVTQEIYITKETLTKISEMNHSLDIELSRLKKHVDHTIKDFQKAKDFSPVHKSKFGNFKNAVKKVQGRERSELQGMKFKWN--TKQLYERGVLKTIRGEKLAELTVKVFGSSGPKFPDIIFKISTSDGSRFGIQMIDKR---KGPDKRYSDDVDSFSFKDLIKTQVEPKIETWKLFHSNVVVNNSQLLHLIVSFFYKRNAL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* . . : * :*: : * : .. : . .: . * . .. . .* : . : : : * : ..: * * * : : : * . : * : :* : : : .*: : . :*: .:*..::. : . .. .: : ::: :: :.. :*: ::: : . . * * : .. . :. * . . : : :* . . : : . .: : : : : .:*... :: : . . . .* : :. . . : . . : : :* :: : *. : : : : . . : : : .: : :: . . :.. . . . : . : . *.. . : . : ::.* * :*.:. : :*. :* : * . : : :*: * .*. : ::. : .:: **: :* :. * *: . .*.: .:::*.:**: *** :.: * .. *: . :: :::::.:: *:.: *..:. : * :.. : *::***:**..* * * :: *: :.:. : * * . ** : ::. *:: *: :. . :..: ... . : :: .. . : :: : : :.* : ..::* .:*: . ..* . .: ..: :: :. : : . .:. :* :*::.. : * : : : :..:* ::. :* : :. . :.: :. : : * . : * * .* :* * .: .:: : . * ::. * *:*: : * : : ::: : :: : :. . * : ::* . : .:. : : : : :: : : : . ::: . : : :. . :* :: . : : : : : :. *: . . . . : ..: :: . : : . :: : : . * : : . . :: :: : . . * : . . *. : ..* . : . . * * :. * . ::: . :: *:: : : :.... ** . *:.*: . * : ", "identical_positions": 105, "similar_positions": 463, "identity": "5.86%" }, { "cls_id": "homologset.agr.SGD:S000006164", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G2B2-1", "uniprot_id": "A0A8I6G2B2_RAT", "id": "A0A8I6G2B2-1", "name": "Signal recognition particle subunit SRP68", "aln": "MLWNVETQLSHQLNPGRAGAHQHTAKAREKNEAESVSVPSTRPGRCRSLPLLVVSPPPSHPALRLRGKMAAEKQIPGGGSGGGGSGGGG-GGGGSGGGRSAGGDENKENERPSAGSKANKEFGDSLSLEILQVIKESQQQHGLRHGDFQRYRGYCSRRQRRLRKTLNFKMGNRHKFTGKKVTEELLT----DSRYLL--LVLMDAERAWSYAMQLKQEANTEPRKR----FHLLSRLRKAVKHAEELERLCESSRVDAKTKLEAQAYTAYLSGMLRFEHQEWKAAIEAFNRCKTIYEKLASAFTEEQAVLYNQRVEEISPNIRYCAYNIGDQS----AINELMQMRLRSGGTEGLLAEKLEALITQTRAKQAATMSEVEWRGRTVPVKIDKVRIFLLGLADNEAAIVQAESEETKERLFESMLSECRDALQAVREELKPDQKQRDYTVDGESGKVSNLQYLHSYLTYIKLSTAIRRNENMAKGLHR-----ALLQQQPEDDSKRSPRPQDLIRLYDIILQNLVELLQLPGLEEDRTFQKEIGLKTLVFKAYR-CFFIAQSYVLVKKWSEALVLYDRVLKYASEVSSHGGAFKNSLKDLPDVQELITQVRSEKCSLQAAAILDANESHQTDTAS-QVKDNTPLVERFETFCLDPSLVTKQASLVHFPPGFQPIPCKPLFFDLALNHVAFPPLED-------------KLEQKTKSG--LTGYIKGIFGFRS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMA6-1", "uniprot_id": "SRP68_MOUSE", "id": "Q8BMA6-1", "name": "Signal recognition particle subunit SRP68", "aln": "--------------------------------------------------------------------MAAEKQIPGGGSGGGGSGSGG-GGGGSGGGRSAGGDENKENERPSAGSKANKEFGDSLSLEILQIIKESQQQHGLRHGDFQRYRGYCSRRQRRLRKTLNFKMGNRHKFTGKKVTEELLT----DNRYLL--LVLMDAERAWSYAMQLKQEANTEPRKR----FHLLSRLRKAVKHAEELERLCESNRVDAKTKLEAQAYTAYLSGMLRFEHQEWKSAIEAFNKCKTIYEKLASAFTEEQAVLYNQRVEEISPNIRYCAYNIGDQS----AINELMQMRLRSGGTEGLLAEKLEALITQTRAKQAATMSEVEWRGRTVPVKIDKVRIFLLGLADNEAAIVQAESEETKERLFESMLSECRDALQAVREELKPDQKQRDYALDGESGKVSNLQYLHSYLTYIKLSTAIRRNENMAKGLHR-----ALLQQQPEDDSKRSPRPQDLIRLYDIILQNLVELLQLPGLEEDRTFQKEISLKTLVFKAYR-CFFIAQSYVLVKKWSEALVLYDRVLKYANEVSSHGGASKNSLKDLPDVQELITQVRSEKCSLQAAAILDANDSHQTDTSS-QVKDNTPLVERFESFCLDPSLVTKQANLVHFPPGFQPIPCKPLFFDLALNHVAFPPLED-------------KLEQKTKSG--LTGYIKGIFGFRS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHB9-1", "uniprot_id": "SRP68_HUMAN", "id": "Q9UHB9-1", "name": "Signal recognition particle subunit SRP68", "aln": "--------------------------------------------------------------------MAAEKQVPGGGGGGGSGGGGGSGGGGSGGGRGAGGEENKENERPSAGSKANKEFGDSLSLEILQIIKESQQQHGLRHGDFQRYRGYCSRRQRRLRKTLNFKMGNRHKFTGKKVTEELLT----DNRYLL--LVLMDAERAWSYAMQLKQEANTEPRKR----FHLLSRLRKAVKHAEELERLCESNRVDAKTKLEAQAYTAYLSGMLRFEHQEWKAAIEAFNKCKTIYEKLASAFTEEQAVLYNQRVEEISPNIRYCAYNIGDQS----AINELMQMRLRSGGTEGLLAEKLEALITQTRAKQAATMSEVEWRGRTVPVKIDKVRIFLLGLADNEAAIVQAESEETKERLFESMLSECRDAIQVVREELKPDQKQRDYILEGEPGKVSNLQYLHSYLTYIKLSTAIKRNENMAKGLQR-----ALLQQQPEDDSKRSPRPQDLIRLYDIILQNLVELLQLPGLEEDKAFQKEIGLKTLVFKAYR-CFFIAQSYVLVKKWSEALVLYDRVLKYANEVNSDAGAFKNSLKDLPDVQELITQVRSEKCSLQAAAILDANDAHQTETSSSQVKDNKPLVERFETFCLDPSLVTKQANLVHFPPGFQPIPCKPLFFDLALNHVAFPPLED-------------KLEQKTKSG--LTGYIKGIFGFRS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSS2-1", "uniprot_id": "SRP68_DROME", "id": "Q9VSS2-1", "name": "Signal recognition particle subunit SRP68", "aln": "--------------------------------------------------------------------MVVQEDNPNTG-------------------------DVQEKTETAPVAEPSKIF----TVEILHMIKDAQQQHGLRHGDFQRYRGYCSRRIRRLRKALKYPQGDKRHFKRRDVTIGQLTGKKADERFIH--IPLICAERAWAYAMQLKQESNTEPRKR----FHLVNKLRRACFYALQLQELCNTEAFDARTKLECEAYVAWMHGTLHFELQLWKTAGEHLKRAQVVYENLGKALPEDEQELYRAKVNEFTPNLRYCAYNISGGASGG-KIDEILELRAQG------VLENLDVLVSQTKTESSEGLQTIDWRGRKVTVRPEKVRLFLLSAQELDKSLAKTTKQDAKIELIERILMDCKDAIQAVRDEIKQDPKLRSLTTG---QTVSGVQYLLAYLSYIRHSRTLQRNLCLVEQAKLNFYDPNLQSQQNVGDGKR-VRPQDLARLYEIILQNVTEMQQINGLEDDATYQSEVENLAITFKAFR-CYYIALTLIDIKKWKEAVALYERASNYATEALK--GKSSPEFQLQEELKKVVSAIDGCKFSAHAYSVLEDDNSEESGTTTKSQKTTKPLYERLSLYKEDQSLHTKAPNVFKLTPDMEPIPCKPIFFDLAMTYVELPSLEG-------------KLESPGKKGASITGFVKGFLGWGGGGNK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38687-1", "uniprot_id": "SRP68_YEAST", "id": "P38687-1", "name": "Signal recognition particle subunit SRP68", "aln": "--------------------------------------------------------------------MVAYSP-------------------------------------------------------IIATYGNRAEQFLETDSDFAKYHAKLNKKLQHLRSRCHLVTKDTKKYSSKNKYGEINSEDYDNKTKLIGVLILLHAERDLALAETLKLRARQRGKLKKSEEKVLSTRLKKACKTADKLVNVTQNE-QQWITRAQYLAFAKLVHSEYLINGKRFKRKDNAKISNNLALVFAALEHLKNLSLLAEEVVDNIVNKYQYSLKQYAGNLITTPEINNFIVERVQSDEN---KDDELVKLLLDNGFNMKKITTSTEDQKVTTNINWRSFNAKIIDAEVAQFLEQGLSIHPTQITQYTQRLSKLEKALDRH-EFFIANHDDQDDIDEMVENSSENNQIILAYIKYNILLTSISRERDLFTHLWN------QWLKLNTSLPSKLTKYKEMERIVKNLTKYLSDIMELPGVYSDDELLSQLDLCKLYFQLFLNTGCLSVLYQSKGRYMEALALYVDAYRRLENKLSEIESLDEILLPANLLSLNSVRSLQKRIENGGNSVITLAEYEKRNHGGSLGKYDLTVIEKLDSKKILP-TDIQLKNLFPLKPKMLPIPSKPTLFDLAFNYITYDKQEPSASQVKDSVTETESISQTPISNEQTEGEPKKKRGFLGLFGR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. . *: : :*. ..** :*:. .:: ::**. : : :::. :. : :. : : *: *** : * ** .:. . : : * .:*::* * :* .: :.. : *: : *:. : . :: : :* : : . :: * . *::: : :*. : .. *:::: * :. ::* *: :. : : : .. :. ... ::. : . :: * . ..*:: : : : . :. . .. * : :*:.* :: *: : : . .: : ::: *: . : : : :: :: *: .* .:: : *: : :: :: **:.** . . : . . : :. : . . ::: : .: * .: *::. : .:. : * : ***.** :****:.:: * .:.. .. * * *: . ", "identical_positions": 60, "similar_positions": 198, "identity": "8.17%" }, { "cls_id": "homologset.agr.SGD:S000006165", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97858-1", "uniprot_id": "S35B1_MOUSE", "id": "P97858-1", "name": "Solute carrier family 35 member B1", "aln": "-----------------------------------------------------------------------------------------------------------------------------MAASRSLVP------DRLRLPLCFLGVFVCYFYYGILQEKITRGKYGEGPKQ-----ETFTFALTLVFIQCVINAMFAKILIQFFDTAR----VDRTRTWLYAACSVSYVGAMVSSNSALQFVNYPTQVLGKSCKPIPVMLLGVTLLKKKYPLAKYLCVLLIVAGVALFMYKPKK-------VVGIEEHTVGFGELLLLMSLTLDGLTGVSQDHMRAHYQTGSN---------HMMLNINLWSTFLLGAGILFTG--ELWEFLSFAERYPTIIYNILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISSMQWVGTVLVFLGLGLDAKFGKGTKKTSH-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6V7K3-1", "uniprot_id": "S35B1_RAT", "id": "Q6V7K3-1", "name": "Solute carrier family 35 member B1", "aln": "-----------------------------------------------------------------------------------------------------------------------------MAASRSLVP------DRLRLPLCFLGVFVCYFYYGILQEKITRGKYGEGPKQ-----ETFTFALTLVFIQCVINAMFAKILIQFFDTAR----VDRTRTWLYAACSVSYVGAMVSSNSALQFVNYPTQVLGKSCKPIPVMLLGVTLLKKKYPLAKYLCVLLIVAGVALFMYKPKK-------VVGIEEHTVGFGELLLLLSLTLDGLTGVSQDHMRAHYQTGSN---------HMMLNINLWSTVLLGAGILFTG--ELWEFLSFAERYPTIIYNILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISSMQWVGTVLVFLGLGLDAKFGKGTKKTSH-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P78383-1", "uniprot_id": "S35B1_HUMAN", "id": "P78383-1", "name": "Solute carrier family 35 member B1", "aln": "-----------------------------------------------------------------------------------------------------------------------------MASSSSLVP------DRLRLPLCFLGVFVCYFYYGILQEKITRGKYGEGAKQ-----ETFTFALTLVFIQCVINAVFAKILIQFFDTAR----VDRTRSWLYAACSISYLGAMVSSNSALQFVNYPTQVLGKSCKPIPVMLLGVTLLKKKYPLAKYLCVLLIVAGVALFMYKPKK-------VVGIEEHTVGYGELLLLLSLTLDGLTGVSQDHMRAHYQTGSN---------HMMLNINLWSTLLLGMGILFTG--ELWEFLSFAERYPAIIYNILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISPMQWVGTVLVFLGLGLDAKFGKGAKKTSH-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66HX0-1", "uniprot_id": "S35B1_DANRE", "id": "Q66HX0-1", "name": "Solute carrier family 35 member B1", "aln": "-----------------------------------------------------------------------------------------------------------------------------MAAGKAASKPSLWQNERVRFAVCFCGVFVCYFYYGILQETITRADYTHAGKK-----EKFRYATTLVFIQCIINAAFARLLIQFFEGSK----QDHTRSWLYGLCSLSYLGAMVSSNSALQYVNYPTQVLGKSCKPIPVMILGVTILRKKYPMAKYLCVFLIVGGVALFLYKPNKG------SSTSDEHVFGFGEMLLLLSLTLDGLTGVVQDHMRGRFQTGAN---------HMMLNVNMWSTLVLGIAVLWSG--EVWEFLAFTDRYPSIIYNILLFGITSALGQTFIFMTVVYFGPLTCSIVTTTRKFFTILGSVLLFGNVISHMQWFGTILVFLGLGLDAKFGKSPKKTTH-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDD7-1", "uniprot_id": "S35B1_DROME", "id": "Q9VDD7-1", "name": "Solute carrier family 35 member B1 homolog", "aln": "-----------------------------------------------------------------------------------------------------------------------------MNLP-----------ERSRFVIYAVGIFVCYFLYGIVQEKLTRGRYGEEVQTDGSVGERFTYALALVWVQCLCNYVFAKVLLTIR-PQK----EDTTNAGSYVACSLTYLLAMVSTNMAMRWVPYPTAVVGKSAKPIPVMILGVLIGRKSYSWTRYACVLTIVLGVILFMYKEGK-------VSNLPAETTLLGEVLLFLSLSMDGLTGAVQERIRAASAPSGQ---------QMMRAMNFWSTLMLGVAMVFTG--EAKEFMYFTIRHPEAWTHLSLIAVCGVLGQFFIFLMVASFGPLACSVVTTTRKFFTVLCSVLLFGNVLIARQWLGAVLVFAALFVDMLYGKKAPLATAKKPPVEGKLSEEKKLNS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q91ZN5-1", "uniprot_id": "S35B2_MOUSE", "id": "Q91ZN5-1", "name": "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "aln": "MDA------------RWWAVVVLATLP--------SLG-----AGGESPEAPPQSWTQLWLFRFLLNVAGYASFMVPGYLLVQYLRRKNYLETG-RGLCFPLVKACVFGN-------EPKAPDEVLLAPRTETAESTPSWQVLKLVFCASGLQVSYLTWGILQERVMTGSYGATATSPG---EHFTDSQFLVLMNRVLALVVAGLYCVLRKQP-----RHGAPMYRYSFASLSNVLSSWCQYEALKFVSFPTQVLAKASKVIPVMMMGKLVSRRSYEHWEYLTAGLISIGVSMFLLSSGP-------EPRSSPATTLSGLVLLAGYIAFDSFTSNWQDALFA-YKMSSV---------QMMFGVNLFSCLFTVGSLLEQG--ALLEGARFMGRHSEFALHALLLSICSAFGQLFIFYTIGQFGAAVFTIIMTLRQAIAILLSCLLYGHTVTVVGGLGVAVVFTALLLRVYARGR-KQRGKKAVPTEPPVQKV-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FLA1-1", "uniprot_id": "F7FLA1_RAT", "id": "F7FLA1-1", "name": "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "aln": "MDAS-----------RWWAVVVLATLP--------SLG-----AGGESPEAPPQSWTQLWLFRFLLNVAGYASFMVPGYLLVQYLRRKNYLETG-RGLCFPLVKACVFGN-------EPKAPDEVPLAPRTETAESTPSWQVLKLVFCAAGLQVSYLTWGVLQERVMTGSYGATATSPG---EHFTDSQFLVLMNRVLALVVAGLYCILRKQP-----RHGAPMYRYSFASLSNVLSSWCQYEALKFVSFPTQVLAKASKVIPVMMMGKLVSRRSYEHWEYLTAGLISIGVSMFLLSSGP-------EPRSSPATTLSGLVLLAGYIAFDSFTSNWQDALFA-YKMSSV---------QMMFGVNLFSCLFTVGSLLEQG--ALLEGARFMGRHSEFALHALLLSVCSAFGQLFIFYTIGQFGAAVFTIIMTLRQAIAILLSCLLYGHTVTVVGGLGVAVVFTALLLRVYARGR-KQRGKKAVPTEPAVQKV-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TB61-1", "uniprot_id": "S35B2_HUMAN", "id": "Q8TB61-1", "name": "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "aln": "MDA------------RWWAVVVLAAFP--------SLG-----AGGETPEAPPESWTQLWFFRFVVNAAGYASFMVPGYLLVQYFRRKNYLETG-RGLCFPLVKACVFGN-------EPKASDEVPLAPRTEAAETTPMWQALKLLFCATGLQVSYLTWGVLQERVMTRSYGATATSPG---ERFTDSQFLVLMNRVLALIVAGLSCVLCKQP-----RHGAPMYRYSFASLSNVLSSWCQYEALKFVSFPTQVLAKASKVIPVMLMGKLVSRRSYEHWEYLTATLISIGVSMFLLSSGP-------EPRSSPATTLSGLILLAGYIAFDSFTSNWQDALFA-YKMSSV---------QMMFGVNFFSCLFTVGSLLEQG--ALLEGTRFMGRHSEFAAHALLLSICSACGQLFIFYTIGQFGAAVFTIIMTLRQAFAILLSCLLYGHTVTVVGGLGVAVVFAALLLRVYARGRLKQRGKKAVPVESPVQKV-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VEI3-1", "uniprot_id": "S35B2_DROME", "id": "Q9VEI3-1", "name": "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "aln": "MYAYNKMGRVPELVICSFIVVTLLVIHFFSDLLRASLGGYYNQDVTLSQLVESQNSDYAWFLKLLVNCFGYSCVFVPGFLIYKYVGRINYLERGNKTFLHKAINMCITGNSGYDQLDAGTSTADKDRPAASTAPKRTSSQEAVQLLWCFGGLMISYLTWGVLQEKIMTQNY-LNFTGES---AKFKDSQFLVFSNRLLAFLVALAYLQWQPSPV----RHRAPLYKYSYASFSNIMSAWFQYEALKFVNFPTQVLAKSCKIIPVMLMGKIMSKAKYESYEYVTALLISLGMIFFMSGSSD-------SSKASGVTTLTGIFLLSMYMVFDSFTANWQGSLFKSYGMTPL---------QMMCGVNLFSSIFTGASLSMQG--GFMDSLAFATEHPKFVFDMVVLSVCSAVGQLFIYHTIDVFGPVVFTIIMTLRQAVAIMLSCFIYQHSISLLGIFGVLIVFVAIFLRVYCTQRLRAIRKRAEANKPKMAV------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12520-1", "uniprot_id": "HUT1_YEAST", "id": "Q12520-1", "name": "UDP-galactose transporter homolog 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MAGSTSSLVICAIGIYATFLTWALVQEPLATRTWPNSMGK-------FQFPNVISLIQASVAMMMGYLYLNWKKVEYPPRKMIKDHWKQLMLISFTQSSSGPLATTSLKHVDYLTYMLAKSCKMIPVLLVHLLLYRTPIASQKKVVALLVSLGVTIFTIGGNDGKKLKRSFNESGNDNKLQGFGLLFSSLFLDGLTNATQDKLLKANKAKEKGKQTLITGAHLMFTLNLFVILWNILYFIVIDCKQWDNAVSVLTMDPQVWGYLMLYSFCGAMGQCFIFYTLEQFGSLVLIMITVTRKMVSMILSIIVFGKSVRFQQWVGMFIVFGGITWEALNKKKANIPKAKSA--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *: :: :.::** : : * . : : .. *.: : ::: * : * ::.*:.* ***::: : : . . : *: :* * ** : :*.:* * : ::* :*:: . . . : . . : .. .. ** **: : **. . :: . *: .::: * ::: : : .* :** .: ", "identical_positions": 33, "similar_positions": 80, "identity": "6.64%" }, { "cls_id": "homologset.agr.SGD:S000006167", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BHC7-1", "uniprot_id": "RHBL4_MOUSE", "id": "Q8BHC7-1", "name": "Rhomboid-related protein 4", "aln": "-----------------MQRRTRGINTGLLLLLSQVFQIGINNIPPVTLATLAVNVWF----FLNPWKPLYHSCISV-EKCYQQKDWQRLLLSPLHHGDDWHLYFNMVSMLWKGVKLERRLGSRWFAYVIATFSLLTGVVYLLLQFTVAELLNQPDFKRNCAVGFSGVLFALKVLS-NHYCPGGFVNILGFPVPNRFACWAELVAIHFCTPGTSFAGHLAGILVGLMY------TQGPLKKIMDTCAGIFISHAGPSGQQNHFNNAGPSG---YQNHYADGRPVTYDATYRNYDVYTAGLSEEEQLERALRASIWDRG-----------------NTRNGPMPYGFRLPPEEMRRQRLHRFDGQ-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TEB9-1", "uniprot_id": "RHBL4_HUMAN", "id": "Q8TEB9-1", "name": "Rhomboid-related protein 4", "aln": "-----------------MQRRSRGINTGLILLLSQIFHVGINNIPPVTLATLALNIWF----FLNPQKPLYSSCLSV-EKCYQQKDWQRLLLSPLHHADDWHLYFNMASMLWKGINLERRLGSRWFAYVITAFSVLTGVVYLLLQFAVAEFMDEPDFKRSCAVGFSGVLFALKVLN-NHYCPGGFVNILGFPVPNRFACWVELVAIHLFSPGTSFAGHLAGILVGLMY------TQGPLKKIMEACAGGFSSSVGYPGRQYYFNSSGSSG---YQDYYPHGRPDHYEEAPRNYDTYTAGLSEEEQLERALQASLWDRG-----------------NTRNSPPPYGFHLSPEEMRRQRLHRFDSQ-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VEK2-1", "uniprot_id": "RHBD2_MOUSE", "id": "Q8VEK2-1", "name": "Rhomboid domain-containing protein 2", "aln": "---------------------------MAAPGPASRFWCSCPEVPSATFFTALLSLLVSGPRLFLLQPPLAPSGLSLRSEALRNWQVYRLVTYIFVYENPVSLLCGAIIIWRFAGNFERTVGTVRHCFFTLIFTVFSAIIYLSFES-VSSLSKLGEVED--ARGFTPVAFAMLGVT-SVRSRMRRALVFGVVVPSVLVPWLLLCAS-WLIPQTSFLSNVSGLLIGLSYGLTYCYSLDLSERVALKLDQKFPFSLMRRIPLFKYISGSSAERRAAQSRRLNPAPGSYPTQSCHPHLTPSYPVTQMQHASGQKLASWPPGHMPSLPPYQPASGLCYVQNHFGPNPNASSVYPASAGTSQGVQPPSPISCPGTVYSGALGTPGATGSKESSKVAMP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZQG3-1", "uniprot_id": "D3ZQG3_RAT", "id": "D3ZQG3-1", "name": "Rhomboid domain-containing protein 2", "aln": "MGDRRKEAEIAEEGGECRGGTREGLAAMAASGPASRFWCSCPEVPSATFFTALLSLLVSGPRLFLLQPPLAPSGLSLRSEALRNWQVYRLVTYIFVYENPISLLCGAIIIWRFAGNFERSVGTVRHCFFTLIFTVFSAIIYLSFES-VSSLSKLGEVED--ARGFTPVAFAMLGVT-SVRSRMRRALVFGVVVPSVLVPWLLLCAS-WLIPQTSFLSNVSGLLIGLSYGLTYCYSLDLSERVALKLDQKFPFSVMRRIPLFKYISGSSAERRAAQSRRLNPPPGSYPTQGCHTHLTPSHPVTQMQHASGQKLASWPPGHLPSLPPYQPASGLCYVQNHFGPNPNASSVYPASAGTSQGLQPPSPISCPGSVYSGVLGTPGATGSKESSKVAMP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12270-1", "uniprot_id": "RBD2_YEAST", "id": "Q12270-1", "name": "Rhomboid-type serine protease 2", "aln": "-----------------------------MNWKSYVFPGGHPPAALTTGLVVFLTAIY-----LLSFIFALREDLSLAPESLFKLQMSRLSLYPLIHLSLPHLLFNVLAIWAPLNLFEETHGTVYTGVFLNLSALFAGILYCLLGK-----LLYPEALVAGASGWCFTLFAYYSFKESQIRPRTRIFRTDYSIPTLYTPLVLLVAIAVVIPGSSFWGHFFGLCVGYAIG----------------YKESWFNKITPPGWIITKIEKSLDG---LIRLIPWGIKYYRDEDIDRTKDYEPLMSTET------------------------------------PLPLHNDNSGTVLGTA-------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . . .* . :. : . :*: :. : : ** : : . * . : :*. *: . ::::.::* : : * *: . ** .. . . :*. . * * * :** .:. *: :* : . . . . . : * * ", "identical_positions": 23, "similar_positions": 55, "identity": "5.85%" }, { "cls_id": "homologset.agr.SGD:S000006168", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61962-1", "uniprot_id": "DCAF7_HUMAN", "id": "P61962-1", "name": "DDB1- and CUL4-associated factor 7", "aln": "------------MSLHGKRKEIYK-------------------------------------------------YEAPWTVYA-MNWS---VRPDK-RFRLALG----------------SFVEEYNNKVQLVGLDEESSEFICRNTFDHP-------------------------YPTTKLMWIPDTKGVYPDLLATSGDYLRVWRVGETETRLECLLN------NNKNSD------------FCAPLTSFDWNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQ-----------------HHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTA-ADDHQALIWDI---------------------------------------------------QQMPRAIEDPILAYT-AEGEINNVQWASTQPDWIAICYNNCLEILRV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61963-1", "uniprot_id": "DCAF7_MOUSE", "id": "P61963-1", "name": "DDB1- and CUL4-associated factor 7", "aln": "------------MSLHGKRKEIYK-------------------------------------------------YEAPWTVYA-MNWS---VRPDK-RFRLALG----------------SFVEEYNNKVQLVGLDEESSEFICRNTFDHP-------------------------YPTTKLMWIPDTKGVYPDLLATSGDYLRVWRVGETETRLECLLN------NNKNSD------------FCAPLTSFDWNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQ-----------------HHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTA-ADDHQALIWDI---------------------------------------------------QQMPRAIEDPILAYT-AEGEINNVQWASTQPDWIAICYNNCLEILRV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32TDP9-1", "uniprot_id": "A0AB32TDP9_DANRE", "id": "A0AB32TDP9-1", "name": "DDB1- and CUL4-associated factor 7", "aln": "------------MSLHGKRKEIYK-------------------------------------------------YEAPWTVYA-MNWS---VRPDK-RFRLALG----------------SFVEEYNNKVQLVGLEEESSEFVCRNTFDHP-------------------------YPTTKIMWIPDTKGVYPDLLATSGDYLRIWRVNDTETRLECLLN------NNKNSD------------FCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQ-----------------HHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAVADDHQALIWDI---------------------------------------------------QQMPRAIEDPILAYT-AEGEINNVQWASTQPDWIAICYNNCLEILRV-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VR53-1", "uniprot_id": "Q9VR53_DROME", "id": "Q9VR53-1", "name": "DDB1- and CUL4-associated factor 7", "aln": "-----------MSSTAGKRKEIYK-------------------------------------------------YLAPWPLYS-MNWS---VRPDK-RFRLALG----------------SFIEEYNNKVQIISLDEDTSEFSAKSTFDHP-------------------------YPTTKIMWIPDSKGVYPDLLATSGDYLRVWRAGEPDTRLECVLN------NNKNSD------------FCAPLTSFDWNEVDPNLVGTSSIDTTCTIWGLETGQPHARV-YVAGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPA-----------------HTALLRLAWNKQDPNYLATVAMDSCEVIILDVRVPCTPVARLSNHRACVNGIAWAPHSSCHICTA-GDDHQALIWDI---------------------------------------------------QQMPRAIEDPILAYTAAEGEVNQIQWGATQPDWIAICYNKACEILRV-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12523-1", "uniprot_id": "YP247_YEAST", "id": "Q12523-1", "name": "WD repeat-containing protein YPL247C", "aln": "MDPFHNGNKRSSISFGSSQRQPYNKNNYLSGTNGPSSAAQDQGRGPSPFGMSGNTTNGGNSKRNSGCDLSATYYASRSPMYSPLDFSPPVFSPNHSQLQQARGYAANIPVVSNLMNPSMASVCEYQSHYPLFGLDWSADDYVCLGSYKEDSRNKLQVLHSNDLLSWESVVDADVVYPVSKIQWVPS--QLYPRKLATCSDSLRIWSVSPEERQFQEQINLSLCKYNRQHPANPAAADDMKVIGTFPPITSFDWNTVDTNLIISSSIDTTCIVWDLQS----------SHYVKTQLIAHDSEVFDVRFLTKS--TQLFASCGGDGSVRVFDLRSLAHSTIIYEPPSSSVSGATAGTITPSSKGSDALLRLEPSPYDPNVLATFAADSNKIIILDMRNPESPILNLQGHGSSVNGIKWHPTKRNVLLSC-GDDCQVLYWDLNSSFMEINAAGSKSPSIHGTSLEDPDGDTEMTDGGAGSGLNEDPLSLNNNSKQVCKTLETPNMMYANKTQEINNIAWRPQRGDWFGCVSGKKFQNVRVL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ..::: *: * : .:*: :::* . *:: ::: * * : : **:.: :..*: .:.:: . .::.. **.:*: *:*. :** ***..* **:* .. : ::: :* *.::. .*:****** **. *: :******* :*.*:: : :*********.**:*: * . ::*** *.*****:**** * ******* * .**** . *** ***.* *. :::***:* * :*: .*..* :.**** * * . : :. .** *.* **: :*: :::* * : *: *:*:: * . : **:. .: : :** ", "identical_positions": 124, "similar_positions": 118, "identity": "23.05%" }, { "cls_id": "homologset.agr.SGD:S000006170", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AWA9-1", "uniprot_id": "RBGP1_MOUSE", "id": "A2AWA9-1", "name": "Rab GTPase-activating protein 1", "aln": "MDD----KASVGKISVS------SDSVSTLNSEDFVLVSRQGDETP---------------STNNGSDDEKTGLKIVGNGSEQQLQKELADVLMDPPMDD----------------QPG-ERSQLDGEGDGPLSNQLSA-SSTINPVPLVGLPKPEMSLPVKPGQGDSEVSSPFTPVADED---------------------SVVFNKLTYLGCASVNAPRSEVEALRMMSILRSQC-QISLDVTLSVPNVSEGTVRLLDPQTNTEIANYPIYKILFCVRG---HDGTPESDCFAFTESHYNAELFRIHVFRCEIQEAVSRILYSFATAFRR-------SAK-QTPLSATAAPQTP----DSDIFTFSVSLEIKEDDGKGYFSAVPKDKDRQCFKLRQGIDKKIVICVQQTAN---KELAIERCFGLLLSPGKDVRNSDMHLLDLESMGKSSDGKS-----------------YVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQEPVRFLLETKVRVCSP-NERLFWPFS-KRSTTENFFLKLKQIKQ-KEKKNNADTLYEVVCLESESERERRKTTASPSVRLPQSGSQSSMIPSPPEDDEEEDNDEPLLSGFGDVSKECAEKILETWGELLSKWHLNLSVRPKQLSSLVRSGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKESPQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQS-------FLAAVLLLHMP-EEQAFSVLVKIMFDYGLRELFKQ---------------NFEDLHCKFY-------------------------------------------------QLERLMQEYIPDLYNHFL---------------------------------------------------DISLEAHMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFFRVQLPKRYRSEENAKRLMELACNTKISQKKLKKFEKEYHTMREQQAQQEDPIERFER-----------------------------------------------------------------------------------------------------ENRRLQEANMRLEQENDDLAHELVTSK--------IALRKDLDNA---EEKADALNKELLMTKQKLIDAEDEKRRLEEESAQLKEMCRRELD------------KAESEIKKNSSIIG-----------DYKQICSQLSERLEKQQTANKVEIEKIRQKVDDCDRCRDFFNKEGRVKG-------------------ISSAKGVSDEDTDEEKETLKNQLREMELELAQTKLQLV----EAECKIQDLEHHLG--LALSEVQAAKKTWFNRTLSSIKT--ATGVQGKE------------------------TC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZX42-1", "uniprot_id": "D3ZX42_RAT", "id": "D3ZX42-1", "name": "Rab GTPase-activating protein 1", "aln": "MDD----KASVGKISVS------SDSVSTLNSEDFVLVSRQGDETP---------------STNNGSDDEKTGLKIVGNGSEQQLQKELADVLMDPPMDD----------------QPGMERSHLDGEGDGPLSNQLSA-SSTINPVPLVGLQKPEMSLPVKSGQGDSEVSSPFTPVADED---------------------SVVFNKLTYLGCASVNAPRSEVEALRMMSILRSQC-QISLDVTLSVPNVSEGTVRLLDPQINTEIANYPIYKILFCVRG---HDGTPESDCFAFTESHYNAELFRIHVFRCEIQEAVSRILYSFATAFRR-------SAK-QTPLSATAAPQTP----DSDIFTFSVSLEIKEDDGKGYFSAVPKDKDRQCFKLRQGIDKKIVICVQQTAN---KELAIERCFGLLLSPGKDVRNSDMHLLDLESMGKSSDGKS-----------------YVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQEPVRFLLETKVRVCSP-NERLFWPFS-KRSTTENFFLKLKQIKQ-KEKKNNADTLYEVVCLESESERERRKTTASPSVRLPQSGSQSSMIPSPPEDDEEEDNDEPLLSGFGDVSKECAEKILETWGELLSKWHLNLNVRPKQLSSLVRSGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKESPQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQS-------FLAAVLLLHMP-EEQAFSVLVKIMFDYGLRELFKQ---------------NFEDLHCKFY-------------------------------------------------QLERLMQEYIPDLYNHFL---------------------------------------------------DISLEAHMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFFRVQLPKRYRSEENAKRLMELACNTKISQKKLKKFEKEYHTMREQQAQQEDPIERFER-----------------------------------------------------------------------------------------------------ENRRLQEANMRLEQENDDLAHELVTSK--------IALRKDLDNA---EEKADALNKELLMTKQKLIDAEDEKRRLEEESAQLKEMCRRELD------------KAESEIKKNSSIIG-----------DYKQICSQLSERLEKQQTANKVEIEKIRQKVDDCDRCRDFFNKEGRVKG-------------------ASSVKGVSDEDTDEEKETLKNQLRELELELAQTKLQLV----EAECKIQDLEHHLG--LALSEVQAAKKTWFNRTLSSIKT--ATGVQGKE------------------------TC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AC58IFA0-1", "uniprot_id": "A0AC58IFA0_DANRE", "id": "A0AC58IFA0-1", "name": "", "aln": "MDD----SSSLGRVSGS------TESVSTVTSEEFVLVPPSAGGSP---------------SSSEG----RPRLKMSWNGSEQ-LERAMEEVLDD--------------------------------VADGAGAEQEKG-CTQIRPPSLDTAPHESSAALLES-----------PTVPEEE---------------------SVQFSKLSYLGCTWVKAPRSETEAQKAMATLRAES-AIPIPVILHVPNGSDGCVRIVDQASGTEIASFPIYKVLFCARG---CEGSVESDCFSFTESYRSSEDFQIHVFSCHIKEAVSRILYSFSTAFKR-------SAKAATEMQDSPLPLSP----DSDVFTFSVSLEVREDDGKGNFSPVPKDRDKYYFKLRQGVQKKVSVVVQQLNN---KELVIERCFGMLLSPGQKVRNSDMHLLDMESMGKNADGKA-----------------YVITGIWNPNTPAFQPLNEDTPKDKQVYMTVAVDLVVTEVVEPVRFLMEALVRVYPA-NER-FWYFS-RKAFCETFYLKLKQGSV-KGSQD--DMMYEVVSLEKHSECG--------------SQARGRLQSPTEEEEPEEDSDSEISSGTGDVSKDCPEKILESWGGILNRWQGNLLTRPKGLSALVKPGIPEALRAEVWQLLSGCHNDQALLEQYRILITKESAQEAVITRDIHRTFPAHDYFKDSGGDGQDSLYKICKAYSVYDEEIGYCQGQS-------FLAAVLLLHMP-EEQAFCVLVKIMFNYGLRELYRN---------------NFEDLHCKFY-------------------------------------------------QLERLLQELLPDLWSHFQ---------------------------------------------------ELNLEAHMYASQWFLTLFTAKFPLCMVFHITDLLLCEGLNIIFNVALALLKTSKEDLLQADFEGALKFFRVQLPKRYRAAENARRLMEQACNIKVPTKKLKKFEKEYQSLRESQLQQEDPIDRYQR-----------------------------------------------------------------------------------------------------ENRRLQEASMRLEQENDDLAHELVTSK--------IALRNDLDQA---EDKADVLNKELLNTKQRLVETEEEKRRQEEETAQLKEVFRRELE------------KAEQEIKKTTAIIA-----------EYKQICSQLSTRLEKQQASTKEELDIVKAKVMACERCREVFSKDGPLQI-------------------PPVSQDNRDTDLDEEKDSLKAQLRELELELAQTKLQLV----EAKCKIQELEHQRG--VLMTEVQAAKNSWFSKTLGSLKN--SASNQSPS------------------------SPKEGP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JNN5-1", "uniprot_id": "A8JNN5_DROME", "id": "A8JNN5-1", "name": "", "aln": "MDDNLSTKSSESSITTSGEYEIVTDSNVASPMEQVKQVVNQEGTQPEVGGKPPTSLSALALSSPEAGGDRSPTLDMAHNRNLSDMQHEMTDALKDLELERGVAASGEKSAQRLPSHQQKSLTLPLTGSGGGSVDPEMRFPCTLFTPKSEETLDDASSSNRVGHSVFYDCIDASPACVEEKQDAMKPEKGDTTDEEVSEIDQGCTIFSGVTYLGAANINAPKSETEVYRIMGELNSGSKSVGLKITVSIPNCSEGLVVLHDAESNTIIATYEISSIILYYRG---PVDTVENGCFAFTWLHG-DALFQCHVFRCHIPEAVNQVSACFQKAFQTYPPSMSCSLNSAVDMANSVTSDVSGNPLNTAGYEFIVSLEIRERVAKNSYAAVPRDRG--CFKLRANTDKEVCITVKQTPSNVLQPLHIERCFGVLVAPGKLVVQKDMHLIDMHSMGYIQPGGTGVATESDSNAQQSSSWPYTIRAEWKAQEKAFEQLNLESSKTN---LTVAVDIVMRRIQEPVRFVIETPVTIQSASEMRIMDHFMSKRPMTLRFYLHLKRTEESNWKVNSIDPSEEITEQPGHQQSSSLLKMGMNNLSRIVRSSSIASIEDDCPSDYSSDGDEPLLSGTGEVSKDCSQDTLDEWDPILREWDS--EKRPKNLAPLVRLGVPEALREKIWQKLANVEGRMEMNDKYKILITKETKCETVIQRDIHRTFPAHKCFKEIGGSGQDALFKVSKAYAVHDSEVGYCQGLS-------FIAASLLLHMP-EEDAFCVLVALMYDYGLRDLYKA---------------GFEVLYLRLY-------------------------------------------------QLERLIKDQLPKLHEHFT---------------------------------------------------ACGIETHMYASQWFLTLYTARFPLCFVFHVLDVFLLDGLPVLFQVAVTLLSICESDLRQLDFEGILKYFRVTLPKKCRSSSQARKVMKQACERKI--KKLKQYEEEFLLKKQHKERLEKEAQIYENR--------------------------------------------------------------------------------------------------FGEERRKMQAEIDALNKQLTSAKERAVEKEKKHTGIIQEYKQIIQRQ---EQDMNTLSETLGKVMHMVSNCQDCQQQIDAGNDNAKSDDGKNRG------------QTDAMRNANEHPLG-----------PLDPLNAASQRIRELELELAQAKLAQVEAECKNQDLNHQLSNTLSELQTNRNSWQPWLSKTFNSLQEKVTTRGGHRDNGSGGPMPSFQSYMGQAPTTLSEASSPSG----NQEYKTFAFASVGGSPKLPSKFQATKLRNSIDSLRNIVVPLDTGKTLAE------------------------NLKQQLQQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P97366-1", "uniprot_id": "EVI5_MOUSE", "id": "P97366-1", "name": "Ecotropic viral integration site 5 protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVTTKMTAAFRNPNRRQVATDKVAEKLSSTLSWVKNT--VSHTVSQMASQVASPSASLHTTSSSTTLSTPTQSPSSPSK---------------------------------------------LSPDDLELLAKLEEQNRLIETDSKSLRSVNG-----------------------------------------------------------------------------SRRNSGSSLVSSSSASSNLSHLEEDSWILWGRIVNEWDDVRKKKEKQVKELVRKGIPHHFRAIVWQLLCN-AQSMTIKDQYSELLKMTSPCEKLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDRELVTVRAVL-------SSLDCCCMQMP-EEEAFCVFVKLMQDYRLRELFKP---------------SMAELGLCMY-------------------------------------------------QFECMIQEYLPELFVHFQ---------------------------------------------------SQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQMNQAELMQLDMEGMLQHFQKVIPHQFDG--GPEKLIQSAYQVKYNSKKMKKLEKEYTTIKTKEMEEQGEIKRLRTENRLLKQRIETLEK--------------------------------------------------------------------------------HKCSSTYNEDFVLQLEKELVQARLSEAESQCALKEMQDKVLDIEKKNNSFPD---ENNIARLQEELIAVKLREAEAIMGLKELRQQVRTLEEHWQRHLA---RTSG-----RWKDPPKKNAVN------------ELQDELMSIRLREAETQAEIREMKQRMMEMETQNQINSNQLRRAEQEVNSLQEKVCSLSVKNKGLLAQLSEAKRRQAEIECKNKEEVMAVRLREADSIAAVAELQQH----IAELEIQKEEGKLQGQLNR-SDSNQYIRELKDQIAELTHELRCLKGQRD--------------FSSRPPFDGIHIVSHLIG----------------DDELFHSSDEDFID---------------SSLQESAIGFPLHRKS----------------GPMSLNPALADG----------------SESEA-----------------------EDGMLGPQESDPEAPQKQPPQR-ESYSTTV------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZM01-1", "uniprot_id": "A0A8I5ZM01_RAT", "id": "A0A8I5ZM01-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQLVFFFPFFIVLIKMPLVQQGILTFTGSASVYLAQSLRHSSCLWVATDKVAEKLSSTLSWVKNT--VSHTVSQMASQVASPSASLHTTSSSTTLSTPTQSPSSPSK---------------------------------------------LSPDDLELLAKLEEQNRLIETDSKSLRSVNG-----------------------------------------------------------------------------SRRNSGSSLVSSSSASSNLSHLEEDSWILWGRIVNEWDDVRKKKEKQVKELVRKGIPHHFRAIVWQLLCD-AQTMPVKDQYSELLKMTSPCEKLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSA-------FIVGLLLLQMP-EEEAFCVFFKLMQDYRLRELFKP---------------SMAELGLCMY-------------------------------------------------QFECMIQEYLPELFVHFQ---------------------------------------------------SQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQMNQAELMQLDMEGMLQHFQKVIPHQFDG--GPEKLIQSAYQVKYNSKKMKKLEKEYTTIKTKEMEEQGEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENYLIKRELATIKQQTDAARAKLEQAESTIRELQH--------------------HRHWHKCSSTYNEDFVLQLEKELVQARLSEAESQCALKEMQDKVLDIEKKNNSFPD---ENNIARLQEELIAVKLREAEAIMGLKELRQQVRDLEEHWQRHVA---RTSG-----RWKDPPKRNAVS------------ELQGELMSIRLREAETQAEMREMKQRMMEMETQNQINSNQLRRAEQEVTSLQEKVCSLSLKNKGLLAQLSEAKRRQAEIECKNKEEVMAVRLREADSIAAVAELQQH----IAELEIQKEEGKLQGQLNR-SDSKQYIRELKDQIAELTHELRCLKGQRD--------------FSSRPPFDGIHIVSHLIG----------------DDESFHSSDEDFID---------------SSLQESAIGFPLHRKS----------------GPVSLNPALADG----------------SESEA-----------------------EDGVLGTQESDPEAPEKQIPQR-ESYSTTV------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60447-1", "uniprot_id": "EVI5_HUMAN", "id": "O60447-1", "name": "Ecotropic viral integration site 5 protein homolog", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVTNKMTAAFRNPSGKQVATDKVAEKLSSTLSWVKNT--VSHTVSQMASQVASPSTSLHTTSSSTTLSTPALSPSSPSQ---------------------------------------------LSPDDLELLAKLEEQNRLLETDSKSLRSVNG-----------------------------------------------------------------------------SRRNSGSSLVSSSSASSNLSHLEEDSWILWGRIVNEWEDVRKKKEKQVKELVHKGIPHHFRAIVWQLLCS-AQSMPIKDQYSELLKMTSPCEKLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSA-------FIVGLLLMQMP-EEEAFCVFVKLMQDYRLRELFKP---------------SMAELGLCMY-------------------------------------------------QFECMIQEHLPELFVHFQ---------------------------------------------------SQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQMNQAELMQLDMEGMLQHFQKVIPHQFDG--VPDKLIQAAYQVKYNSKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEK--------------------------------------------------------------------------------HKCSSNYNEDFVLQLEKELVQARLSEAESQCALKEMQDKVLDIEKRNNSLPD---ENNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRHLA---RTTG-----RWKDPPKKNAMN------------ELQDELMTIRLREAETQAEIREIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNKEEVMAVRLREADSIAAVAELRQH----IAELEIQKEEGKLQGQLNK-SDSNQYIGELKDQIAELNHELRCLKGQRG--------------FSGQPPFDGIHIVNHLIG----------------DDESFHSSDEDFID---------------NSLQETGVGFPLHGKS----------------GSMSLDPAVADG----------------SESET-----------------------EDSVLETRESNQVVQKERPPRRRESYSTTV------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ATD7-1", "uniprot_id": "A0A8M3ATD7_DANRE", "id": "A0A8M3ATD7-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVATDKVTGKLSSTLSWVKNS--VSHTVSQMASQVATPS-SLHTTVASSTASLSSPSSASPTQ---------------------------------------------LSPDDVELLAKLEEQNRLLETDSKSLRSVNG-----------------------------------------------------------------------------SRRNSGSSLVSSSSASSNLSHLEEDSWILWGRIVNEWEDVRKKKEKQLKELVRKGVPHHFRAIVWQLLCN-AQNLPIKEQYSELLKMTSPCEKLIRRDIARTYPEHEFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSA-------FIVGLLLMQMP-EEEAFCVFVKLMQEYRLRELFKP---------------SMAELGLCMY-------------------------------------------------QFECMIQEQLPELHVHFQ---------------------------------------------------AQSFHTSMYASSWFLTIFLTSFPLPVATRIFDIFMCEGLEIVFRVGMAILQMNQAELMQLDMEGMLQHFQKVIPHQLDS--GPDKVIQAAYQVKYNAKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIDTLEKESASLADRLIQGQVTRAQEAEENYLVKRELATVKQHIEETSVQLEQAQSTIRQLQQ--------------------P--FAKGNPRYTEESILQLERELVQARLKEAESQCALKEMQDKILYMEQRNTSLPD---ENNVVRLQEELIGVKLREAEALTGLKELRQQVRDLEEHWQRHLA---RTAG-----RWKDSPRKNAAS------------ELQDELMSVRLREAEAQAELRETRQRMLELETQNQIHSNQLRRAELEARNLQDRLHVLSNQNKMLHSELQETKRKQAEIECKNKEEVMAVRLREADNIAAMAELQQQ----ISELEIQKEEGKVQGQLNN-TDSSQYIRDLKDQIADLKHEIRCLRGHQG--------------LPNQHTFDGIHIVNHYGG----------------DNESYQSSDEDGVK---------------LSPHLT-----THQDR----------------GRITLHPNLED-----------------SESEG-----------------------DE------EGD--ALRLTVPSNVSHKTTTV------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "H3BL92-1", "uniprot_id": "H3BL92_MOUSE", "id": "H3BL92-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASPTLSPDSSSQE-ALSAPTCSPTSDSEN--------------------------------------------LSPDELELLAKLEEQNRLLEADSKSMRSMNG-----------------------------------------------------------------------------SRRNSGSSLVSSSSASSNLSHLEEDTWILWGRIANEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQLLCS-ATDMPVKNQYSELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSA-------FIVGLLLMQMP-EEEAFCVFVRLMQEYRLRELFKP---------------SMAELGLCIY-------------------------------------------------QFEYMLQEQLPDLNTHFR---------------------------------------------------SQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQTELMQLDMEGMSQYFQRVIPHQFDS--CPDKLVLKAYQVKYNPKKMKRLEKEYAAMKSKEMEEQIEIKRLRTENRLLKQRIETLEK-----------GQVTRAQEAEENYVIKRELAVVRQQCSSTAEDLQKAQSTIR------------------------QLQEQQENPRLTEDFVAHLETELEQSRLRETETLGALREMQDKVLDMEKRNSSLPD---ENNVARLQEELKALKVREGEAVASARELKLQLQELSDTWQAHLS---RGG------RWKESPRKLVLG------------ELQDELMTVRLREAQALADGREWRQRVVELETQDNIHRNLLNRVEAERAALQEKLQYLAAQNKGLQTQLSESRRKQAEAECKSKEEVMAVRLREADSMAAVAEMRQR----IAELEIQREEGRIQGQLNH-SDSSQYIRELKDQIEELKTEVRLLKGPPT--------------FEDPLAFDGLSLTRHLD------------------EDSLPSSDEELL-----------GVGVGVGAALQDPLYPLSPRD----------------ARFFRSLDRPA-----------------KDSEG-----------------------SS--------DSDADELATPYSNQGLDN--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K1A4-1", "uniprot_id": "A0A0G2K1A4_RAT", "id": "A0A0G2K1A4-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLSTMASPTLSPDSSSQE-ALSAPTCSPTSDSEN--------------------------------------------LSPDELELLAKLEEQNRLLEADSKSMRSMNG-----------------------------------------------------------------------------SRRNSGSSLVSSSSASSNLSHLEEDTWILWGRIANEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQLLCS-ATDMPVKNQYSELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSA-------FIVGLLLMQMP-EEEAFCVFVRLMQEYRLRELFKP---------------SMAELGLCIY-------------------------------------------------QFEYMLQEQLPDLNTHFR---------------------------------------------------SQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQTELMQLDMEGMSQYFQRVIPHQFDS--CPDKLVLKAYQVKYNPKKMKRLEKEYAAMKSKEMEEQIEIKRLRTENRLLKQRIETLEKESAALADRLIQGQVTRAQEAEENYVIKRELAVVRQQCSSTAEDLQKAQSTIR------------------------QLQEQQENPRLTEDFVSHLETELEQSRLRETETLGALREMQDKVLDMEKRNSSLPD---ENNVARLQEELKALKVREGEAVASARELKLQLQELSDTWQAHVS---RGG------RWKESPRKLVLG------------ELQDELMTMRLREAQALADGREWRQRVVELETQDNIHRNLLNRVEAERAALQEKLQYLAAQNKGLQTQLSESRRKQAEAECKSKEEVMAVRLREADSMAAVAEMRQR----IAELEIQREEGRIQGQLNH-SDSSQYIRELKDQIEELKTEVRLLKGPPT--------------FEDPLAFDGLSLTRHLD------------------EDSLPSSDEELLG---------VGVGVGVGAALQDPLYPLSPRD----------------ARFFRSLDRPA-----------------KDSEG-----------------------SS--------DSDADELATPYSNQVLDN--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96CN4-1", "uniprot_id": "EVI5L_HUMAN", "id": "Q96CN4-1", "name": "EVI5-like protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASPTLSPDSSSQE-ALSAPTCSPTSDSEN--------------------------------------------LSPDELELLAKLEEQNRLLEADSKSMRSMNG-----------------------------------------------------------------------------SRRNSGSSLVSSSSASSNLSHLEEDTWILWGRIANEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQLLCS-ATDMPVKNQYSELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSA-------FIVGLLLMQMP-EEEAFCVFVRLMQEYRLRELFKP---------------SMAELGLCIY-------------------------------------------------QFEYMLQEQLPDLNTHFR---------------------------------------------------SQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQAELMQLDMEGMSQYFQRVIPHQFDS--CPDKLVLKAYQVKYNPKKMKRLEKEYAAMKSKEMEEQIEIKRLRTENRLLKQRIETLEK-----------GQVTRAQEAEENYVIKRELAVVRQQCSSAAEDLQKAQSTIR------------------------QLQEQQENPRLTEDFVSHLETELEQSRLRETETLGALREMQDKVLDMEKRNSSLPD---ENNVAQLQEELKALKVREGQAVASTRELKLQLQELSDTWQAHLA---RGG------RWKESPRKLVVG------------ELQDELMSVRLREAQALAEGRELRQRVVELETQDHIHRNLLNRVEAERAALQEKLQYLAAQNKGLQTQLSESRRKQAEAECKSKEEVMAVRLREADSMAAVAEMRQR----IAELEIQREEGRIQGQLNH-SDSSQYIRELKDQIEELKAEVRLLKGPPP--------------FEDPLAFDGLSLARHLD------------------EDSLPSSDEELL-------------GVGVGAALQDALYPLSPRD----------------ARFFRRLERPA-----------------KDSEG-----------------------SS--------DSDADELAAPYS-QGLDN--------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AUU5-1", "uniprot_id": "A0A8M3AUU5_DANRE", "id": "A0A8M3AUU5-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSPSSSPEREGGMAGSVQLEDLN--SPAGLEIDPPFIGSPVLSPDSSSHDAALSAPAASP-ADSEN--------------------------------------------LSPDELELLAKLEEQNRLLEADSKSMRSMSG-----------------------------------------------------------------------------SRRNSGSSLVSSSSASSNLSQLEEDTWILWGRIVNEWDEWRRKKDKLLKELIRKGIPHHFRAIVWQLLCN-ATDMPVKNQYSELLKMSSPCEKLIRRDIARTYPEHDFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSA-------FIVGLLLMQMP-EEEAFCVFVRLMQEYRLRELFKP---------------SMAELGLCIY-------------------------------------------------QFEHLLQEQLPELNVHFR---------------------------------------------------SQSFHTSMYASSWFLTLFLTFLPLPIATRIFDIFMYEGLEIIFRVGIAILQYNQTDLIQLDMEGMSQHFQKVIPHQFDS--CPDKLILRAYQVKYNPKRMKKLEKEYTTIKNKEMEEQIEIKRLRTENRLLKQRIETLEKESAALADRLIQGQVTRAQEAEENYVIKRELAVVRQQCHTASESLEKAQDTIR------------------------ELQQH----KYTEEFVSGLQTQLEQSRLQEAELLGALKEMQDKVLDLEKRNSSLPD---EINVAQLQEELKLVKLREQETLRSFREMQEAVTDLNHCWQHHTS---RGGGGGGGGHWKESPKKNAMN------------ELQDKLMSLRLREAQGQAELKEVKLKNLQLESQNQINGKLLGRHEQESTSLQERLQNALSHNKTLQSQLNEMKRKQAESDCKSKEEVMAVRLREADSMAAMAELRQK----IADLEIQKEEGLIQGQLNH-SDSRQYITELRQQIAELKSEIRQLRGQPSKFQNNGSGVYQDLCLESPASAEGDYLSSDEDPLQSLPVSSLYPNHSSPRLDSQGSTDSDDPAGFRYGPPPSPVQWLPVNSRDIADIHSLSSRDGALDCPIVSPKYCSLCGKVFSSLSRLESHVFRAHGGHHGRALVFRDSKDPVMPCRIKERTFECKECGKVFKRSSTLSTHLLIHSDTRPYPCLYCGKRFHQKSDMKKHTFIHTGEKPHVCKVCGKAFSQSSNLITHSRKHYRPYS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYY9-1", "uniprot_id": "EVI5_DROME", "id": "Q9VYY9-1", "name": "Ecotropic viral integration site 5 ortholog", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLTTTTTASSAESQAKMDVKGGALPGEEN--------------------------------------------LPTSEMDLLAKLEAANKLIESDAKSLNSLHSTH---------------------------------------------------------------------------SRKNSDTSQISLTSSGN--SVAEEDIWTTWATILNDWEGALKRKNPCVSELVRRGIPHHFRAIVWQQLSG-ASDG-DKKQYAEYIKATSACEKVIRRDIARTYPEVEFFKEKDGPGQEALFNVIKAYSLHDREVGYCQGSG-------FIVGLLLMQMP-EEEAFAVLVQIMQQHRMRHMFKP---------------SMSELGLCMY-------------------------------------------------QLENLVQEQIPDMHIHFQ---------------------------------------------------QQGFQTTMYASSWFLTLYTTTLNVNLSCRIMDVFLSEGMEFIFKVALALLLTGKDTLLCLDMEAMLKFFQKELPGRVEA--DVEGFFNLAYSIKLNTKRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRRSYLEVSHQLENANEEVRGLSLRLQENNVSIDSNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAKVEELEEDKKTLRETTPDNSVAHLQDELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQRSESERTTNAVDSTPKKLLTNFFDSSKSSEHTQKLEEELMTTRIREMETLTELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKEELEMAVTREKDMSNKAREQQHRYSDLESRMKDELMNVKIKFTEQSQTVAELKQE----ISRLETKNSEMLAEGELRANLDDSDKVRDLQDRLADMKAELTALKSRGK--------------------FPGAKLRSSSIQ-------------------SIESTEIDFND---------------LNMVRRG------------------------------STELST---------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8I5ZMX5-1", "uniprot_id": "A0A8I5ZMX5_RAT", "id": "A0A8I5ZMX5-1", "name": "TBC1 domain family member 1", "aln": "----------------------MEAITFTARKHPFPNEVSVD----------------FGLQLVGSLPVHSLTTMPMLPWVVAEVRRLSGQCSKK---EPGMKQVRLWVSPSGLRCEPDLRK-------SQPWDPLICSSIFECKPQRVHKLIHNSQDPSYFACLIKEDAAHQQS--LCYVFKADDQ---------------TKVPEIISSIRQAGKIARQEELRCPSEFDDTFAK--KFEVLFCGRVTVAHKKAPPALIDECIEKFNHVS------CGRR------------IDWDAPT-----------GQPSAPGARPMRKSF----SQPGLRS--LAFRK---------EFQDASLRSSTFS------SFDNDIENHLIGGHN----VVQPTDMEENRTMLFTIGQSEVYLISPDTKKIALEKNFKEISFCSQGIRHVDHFGFICRECSGGGGAG-----------------------------------FHFVCYVFQCTNEALVDEIMMTLKQAFTVAAVQQTAKAPAQLCEGCPLQGLHKLCERIEGMNSS-----------------------------------------KTKLELQKHLTTLTNQEQAMIFEEVQKLRPRNEQRENELIISFLRCLYEEKQKEHSHTGEPKQTLQVAAENIGSELPPSASRFRLDSLKNRAKRSLTESLESILSRGNKARGLQDHSASVDLDSSTSSTLSNTSKELSMGDKEALPISESSFKLLGSSDDLSSDSESHI-AEESALLSPQQAFRRRANTLSHFPVECPAPPEPAQTSPGVSQRKLMRYHSVSTETPHERNVDHLPGGESRCCPGQPSDPPPLPPRLNPSASSPNFFKYLKHNSSGEQSGNAVPKSVSYRNALRKKLHSSSSVPNFLKFLAPVDENNTCDFKNTNRDFESKANHLGDTDGTPVKARRHSWRQQIFLRVATPQKACDSPSR-YEDYSELGELPPRSPLEPVCEDGPFGPVQE--------EKKKTSR--ELRELWKKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCLKEVTTVWEKMLSTPGRSKIKFDMEKVHSAVGQGVPRHHRGEIWKFLAEQFHLKHPFPSKQQP------------------------KDVPYKELLKKLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEYEIG----PSLYAAPWFLTVFASQFPLGFVARVFDMIFLQGSEVIFKVALSLLGSHKPLILQHENLETIVDFIKNTLPNLGLVQMEKTISQVFEMDIAKQLQAYEVEYHVLQEELIDSSPLS-DNQRMDKLEKTNSSLRKQNLDLLEQLQVANARIQSLEVTVEKLLTSES---------------------KLKQAVLTLEM----------------ERSALLQMVEELRRQMAQPSTAEPDCTR---LEPTGD--------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z881-1", "uniprot_id": "D3Z881_RAT", "id": "D3Z881-1", "name": "TBC1 domain family member 4", "aln": "----------------------MESPSCIQ-DEPFPHPLEPEPIALAQPGATKPGDKRFRLWYVGGSCLDRRTTLPMLPWLMAEIRRRSLKPEAGGCGAPAAREVLLVLSAPFLRCVPAPGVGVGGGAGSGAVQPNTGVFIFEHKAQHISRFIHNSHDLTYFAYLIKAQPDDPESQMACHVFRATDP---------------NQVPDVISSIRQLSKAAMKEDAKPSKDNEDAFYNSQKFEVLYCGRVIVTHKKAPSSLIDDCKDKFSLHEQQRLKLQGERGGDPGDGDEMGVLEAESPVSPDDGLPEKPDGLVNCPRALPSLASLPALASQPALASSRVCFPERILEDCGFDEQQEFRSRCSSVTGVMQKKVHENNQKTQPRRRHASAPSHVQPSDSEKNRTMLFQVGRFEINLISPDTKSVVLEKNFKDISSCSQGIKHVDHFGFICRESLEPGLS-------------------------------------QYICYVFQCANESLVDEVMLTLKQAFSTAAALQSAKTQIKLCEACPMHSLHKLCERIEGLYPP-----------------------------------------RAKLVIQRHLSSLTDNEQADIFERVQKMKPISDQEENELVILHLRQLCEAKQKTHVHIGEGQ---AIISNSTIPENSTSGGRFKLDVLKNKAKRSLTSSLENIFSRG--ANRMRGRLGSVDSFERSNSLAS--EKDFSPGGSPPGTPPAS---------PLSSAWHTFP-EEDSD--SPQ--FRRRAHTFSHP--------------PSSSRRKLN-----------------LQDGKAHGLR------------------SP----LLRQNSSEQCSDGEGRK------------RTSSTCSN-----------------------ESLS-----AGGTPVTPRRISWRQRIFLRVASPVNKSPSAMQQQKDGLDRTELLPLSPLSPTMEEEPLVIFLSGDEDTEKVEEKKKSK--EIKSLWKKAIHQQILLLRMEKENQKLEARRDELQSRKVKLDYEEVGTCQKEVLIAWDKKLLN-CRTKIRCDMEDIHTSLKEGVPKSRRGEIWQFLALQYRLRHRLPNKHQP------------------------PDTSYKELLKQLTAQQHAILVDLGRTFPTQPYFSVQLGAGQLSLFNLLKAYSLLDKEVGYCQGISFVAGVLLLHMSEEQAFEMLKFLMYDLGFRKQYRPDMMSLQIQMYQLSRLLHDYHRDLYNHLEENEIS----PSLYAAPWFLTLFASQFPLGFVARVFDIIFLQGTEVIFKVALSLLSSQEALVMECENFENIVEFLKSTLPDMNTTEMEKIITQVFEMDISKQLHAYEVEYHVLQDELLESSYACEDNESLEKLERANNQLKRQNMDLLEKLQVAHAKIQALESNLETLLTRET---------------------KMKALIRTLEQ----------------DKMAYQKTVEQIRKLLPADALANCELLLKDLSYPTNDKAKAGNKP------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12344-1", "uniprot_id": "GYP5_YEAST", "id": "Q12344-1", "name": "GTPase-activating protein GYP5", "aln": "---------------------MSSDKSIEKNTDTIASEVHEGDNHS---------------NNLGSMEEEIKSTPSDQYEEIAIIPTEPLHSDKELND------------------------------KQQSLGHEAPTNVSREEPIGISGDEDTQITEQNVNEQRQETREPSSEIDLNEP--------------------LDVEKDVTTDVQAPNGLNIEKEYDAVKENEKVYADTKEVVSSPENREVTGKNSGGEKSSSSK--------------FLDDESGTTTAANANDISISSEVTPERSSENDNNQIHITNEVAAGINLNENKEQKAAIEDGPVTAENLSSETARKVPPIPTQIINEKGDNSSENEVSAIPTTSSPPLPPRQNVATSTSPKLPPRGKQREQPPKTKNAVPPPLEEEMKSEKFRKNFEETKRNSYHHVPLTGSKTAQLESTAEIN------------------------------------LIASRYRKTSHHLNKEGEETRESLQEGQSFLKSTFT-----------------------------------------------------------------------------SFLENLSEYNEVENVNEEDREMFKIDWSFWTQVVNDYATVASNEPENLEAHVTNGIPPQIRGIIWQLMAN-SKSREMEDIYETLLDTECLHEATIRRDLRRTKFVAEDKMES-------LYKVIKVYSVYDPDVGYTQGMG-------FIAAPLLINCENEAESFGLLVGLMKNYGLRELFLP---------------GMPGLMLMLY-------------------------------------------------QFDRLLEEHSPSLYNRLIR---------------------------------------------------EGISSTMYATQWFLTFFAYKFPLEFVLRIFDIVFVEGIEVLLKFAVNLMLKNEETLVKLRFDELLDFLKDELFNYYLMG--NQDDASVVQMGLSNGNSFKGNDDGTFSYNVDLFVHDAMTG-------------------------------------------------------------------------------------------------------------VYITPLTLRRYRGEYVEIHEKEQKKEDHYESLRIQNHQLQR-----EAQKLEHDYSILNKENISAANELIQNRLNMEMLLDEKNDLIN-------------------------------------------TITDIKSQIEEEIRKQNLPNPDASLPKADLREDLERTISRNNE-------------------VMRENGQLEERITELQAEIDELININKEQVSTASLLER-------------------------DSKAKGRKGWTGFKKVFK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . . . : . . . . * : . :: . : . : . . . .* :: : : . . :: :. . . . : . : . . : : ", "identical_positions": 2, "similar_positions": 44, "identity": "0.12%" }, { "cls_id": "homologset.agr.SGD:S000006173", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CPW2-1", "uniprot_id": "FDX2_MOUSE", "id": "Q9CPW2-1", "name": "Ferredoxin-2, mitochondrial", "aln": "-MAASMARG-VSARVLLRAAGGSWGPRAG--------HAAVTSRT-FGTTGERR------AGEEAADSPE----LPRDVVNVVFVDRSGKRIPVRGKVGDNVLYLAQRHGVDLEGACEASLACSTCHVYVSEAHLDLLPPPEEREDDMLDMAPLLQENSRLGCQIVLTPELEGVEFALPKITRNFYVDGHIPKPH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A8N2-1", "uniprot_id": "D4A8N2_RAT", "id": "D4A8N2-1", "name": "Ferredoxin-2, mitochondrial", "aln": "-MAASMARG-VSARVLLRAAGGSWGPRAG--------HAAVTSRT-FGSTGERR------AGEDEADSPE----LPRDVVNVVFVDRSGKRIPVRGRVGDNVLHLAQRHGVDLEGACEASLACSTCHVYVSEAHLDLLPPPEEREDDMLDMAPLLQENSRLGCQIVLTPELEGAEFALPKITRNFYVDGHIPKPH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P4F2-1", "uniprot_id": "FDX2_HUMAN", "id": "Q6P4F2-1", "name": "Ferredoxin-2, mitochondrial", "aln": "-MAASMARGGVSARVLLQAARGTWWNRPGGTSGSGEGVALGTTRK-FQATGSRP------AGEEDAGGPE----RPGDVVNVVFVDRSGQRIPVSGRVGDNVLHLAQRHGVDLEGACEASLACSTCHVYVSEDHLDLLPPPEEREDDMLDMAPLLQENSRLGCQIVLTPELEGAEFTLPKITRNFYVDGHVPKPH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08C57-1", "uniprot_id": "FDX2_DANRE", "id": "Q08C57-1", "name": "Ferredoxin-2, mitochondrial", "aln": "MAAAAAVRAGVNFTQRLNRISPVCRVCPLLRLNRCTGAAVRRAVDGFSAPSRRLRTSIGVCQSEDSSAPEEDAHAQEHIVNVVYIDRSGRRIPVQARVGDNVLYLAHKHGIDLEGACEASLACSTCHVYVSSGHYDRLPEPEEREDDMLDMAPLLQENSRLGCQIILTPELDGMELTLPKVTRNFYVDGHVPKPH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P37193-1", "uniprot_id": "ADXH1_DROME", "id": "P37193-1", "name": "Adrenodoxin-like protein 1, mitochondrial", "aln": "MFCLLLRRSAVHNSCKLISKQIAKP-------------AFYTPHNALHTTIPRR------HGEFEWQDPK----STDEIVNITYVDKDGKRTKVQGKVGDNVLYLAHRHGIEMEGACEASLACTTCHVYVQHDYLQKLKEAEEQEDDLLDMAPFLRENSRLGCQILLDKSMEGMELELPKATRNFYVDGHKPKPH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12184-1", "uniprot_id": "ADRX_YEAST", "id": "Q12184-1", "name": "Adrenodoxin homolog, mitochondrial", "aln": "-MLKIVTRAGHTARISNIAAHLLRTSPSL--------LTRTTTTTRFLPFSTSS-----FLNHGHLKKPK-----PGEELKITFILKDGSQKTYEVCEGETILDIAQGHNLDMEGACGGSCACSTCHVIVDPDYYDALPEPEDDENDMLDLAYGLTETSRLGCQIKMSKDIDGIRVALPQMTRNVNNNDFS----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : . : . *: . :::.:: :.* : *:.:* :*: *.:::**** .* **:**** *. : : * .*: *:*:**:* * *.******* : .::* .. **: ***. :.. ", "identical_positions": 41, "similar_positions": 47, "identity": "21.03%" }, { "cls_id": "homologset.agr.SGD:S000006175", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJQ7-1", "uniprot_id": "TADA1_RAT", "id": "Q5BJQ7-1", "name": "Transcriptional adapter 1", "aln": "-------------------------------------------------------MATFVSELEAAKKNLSEALG-DNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDN--------------VHSHNDFLLAILTRCQILVSTPEGAGSLPWTGGSA-AKPGKP-KGKKKLSS---------VRQKFDHRFQPQNPLSGAQ-------------------QFVAKDPQDDDDLK---------------------LCSHTMMLPTRGQLEGRMIVTAYEHGLD-NVTEEAVSAVVYAVENHLKDILTSVVS----RRKAYRVR-DGHFKYAFGSNVTPQPYLKNSVVAYNNLVEGPPAFPAPCASQNPASHPHTDDAEQQAAFLLACSGDTLPASLPP-----VNMYDLFEALQVHREVIP-THTVYALN------------IERIIMKLWHPNHEELQQDKVHRQRLAAKEGLLLC--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LM9-1", "uniprot_id": "TADA1_MOUSE", "id": "Q99LM9-1", "name": "Transcriptional adapter 1", "aln": "-------------------------------------------------------MATFVSELEAAKKNLSEALG-DNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDN--------------VHSHNDFLLAILTRCQILVSTPEGAGSLPWTGGSA-AKPGKP-KGKKKLSS---------VRQKFDHRFQPQNPLSGAQ-------------------QFVAKEPQGDDDLK---------------------LCSHTMMLPTRGQLEGRMIVTAYEHGLD-NVTEEAVSAVVYAVENHLKDILTSVVS----RRKAYRVR-DGHFKYAFGSNVTPQPYLKNSVVAYNNLVEGPPAFSAPCANQSPASQPHPDDAEQQAAFLLACSGDTLPASLPP-----VNMYDLFEALQVHREVIP-THTVYALN------------IERIIMKLWHPNHEELQQDKVHRQRLAAKEGLLLC--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96BN2-1", "uniprot_id": "TADA1_HUMAN", "id": "Q96BN2-1", "name": "Transcriptional adapter 1", "aln": "-------------------------------------------------------MATFVSELEAAKKNLSEALG-DNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDN--------------VHSHNDFLLAILTRCQILVSTPDGAGSLPWPGGSA-AKPGKP-KGKKKLSS---------VRQKFDHRFQPQNPLSGAQ-------------------QFVAKDPQDDDDLK---------------------LCSHTMMLPTRGQLEGRMIVTAYEHGLD-NVTEEAVSAVVYAVENHLKDILTSVVS----RRKAYRLR-DGHFKYAFGSNVTPQPYLKNSVVAYNNLIESPPAFTAPCAGQNPASHPPPDDAEQQAALLLACSGDTLPASLPP-----VNMYDLFEALQVHREVIP-THTVYALN------------IERIITKLWHPNHEELQQDKVHRQRLAAKEGLLLC--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NWA8-1", "uniprot_id": "TADA1_DANRE", "id": "Q6NWA8-1", "name": "Transcriptional adapter 1", "aln": "-------------------------------------------------------MAAHASELEIAKKNLTDAIG-ENVKHYWANLKLWFKQKISKEEFDLEARRLLAQDN--------------VHVHNDFLLAILTRCQIIVSTSEGPGSLQWSGGSA-SKPGKPSRGKKKFPS---------VRQKFDHRFQPQNPLAGVP-------------------VFSPREAE-EEELK---------------------LSAQTLLLPSRGQLEARMMVSAFESDLD-SVAEDAVSCMLCALQVHLKDILTALVS----RRKAYRLR-DGHFLYAFGSDVTPRPYLKNSLPAYHSATECPPASASLPAAAP--ARVCPDEAEQNAALLLACSADTAAPPLQP-----VSVYDLLEALQVQRRVMP-SHSMYALN------------MERILARLWHPSHEELEQDHIHRQHLALRDGLVT---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IP99-1", "uniprot_id": "TAD11_DROME", "id": "Q8IP99-1", "name": "Transcriptional adapter 1-1", "aln": "---------------------------------------------------------MLTDRVLATKEALVVALG-DNWERYRANMKNWFRSRWTKEEFDAESRKILTPDK--------------LHLHNQFLLALLNKIDAFAP-LENPPAVQTSSSSG-NRSKRRKRSCRTFAERLNFELSDVLDFVAEDNMQIIRPPTTIG-------------------IPSDQQQQQLQSQR---------------------YCAQELFLPDAGFIMGRFLIGAWEIGLV-SVDDNVAEYVAMAVQVLLKDLLSAIIK----KRKHYKTSGEGNFYYDVGAPLR-DPSLRN-TVTRQKVDDTPLELDKELNTANFMRRQNDD------VTFLSACEEVQPTERTV-----ITLKDCQLALR-DRNLIG-SHAVYSIN------------MERLNMMMH----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IPA1-1", "uniprot_id": "TAD12_DROME", "id": "Q8IPA1-1", "name": "Transcriptional adapter 1-2", "aln": "---------------------------------------------------------MLTDRVLATKEALVVALG-DNWERYRANMKNWFRSRWTKEEFDAESRKILTPDK--------------LHLHNQFLLALLNKIDAFAP-LENPPAVQTSSSSG-NRSKRRKRSSRTFAERLNFELSDVLDFVAEDNMQIIRPPTTIG-------------------IPSDQQQQQLQSQR---------------------YCAQELFLPDAGFIMGRFLIGAWEIGLV-SVDDNVAEYVAMAVQVLLKDLLSAIIK----KRKHYKTSGEGNFYYDVGAPLR-DPSLRN-TVTRQKVDDTPLELDKELNTANFMRRQNDD------VTFLSACEEVQPTERTV-----ITLKDCQLALR-DRNLIG-SHAVYSIN------------MERLNMMMH----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12060-1", "uniprot_id": "HFI1_YEAST", "id": "Q12060-1", "name": "SAGA complex subunit HFI1", "aln": "MSAIQSPAPKPLQPTYPAASPASTNAYMKPGLIGSPAVSNHTEPNNGNNETAEPQGPNQRIDLGAMIEELTSLLGKESWTKYAQIISLFILGKLSRKELSNELELVFSPSAASLEKSNTNHHHSLVRLHNQLLLGIFANSLRENPLGRNGNESSWGFGNGSNNPNNKLKRINKHNSQIEVYKKIVMSLPLNDRNRLKMITKEAGKRGFIFCSVFQARLNNIPKIPIVTNPESLKRVKSNNLKTPLEWSQDIMNGFNVPLASESHSLPDTDSFYLRMVGIAREHGLVGTVDARCVELISLALDQYLKNIIEFTIDTVRYRRKKYSDYYDLNESGLYKSVSEMAADKRDAKIKQLDDDKNEDECADEAKSINNGNNSSKDDIGDISMSSITKAGEAVNEELHENRTISLTNEDIYDSLSIFPNLVEPSGSYYALTNLGLVNDDELVDMKSNIDDLPDFLNEKPTFTPLDERNVGTRHELNWLIKGILTED", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * :* :. :* :. :: : :::*:. * . ::: . :: **::**.:: . . . ... .. . : .. . : :.. : : : . : .:. ** . : *:: * * .* .* .. : *:: **::: :. :** * : : : . :: . . . * :: . :. :. * :* .:: : : *::. :: : ", "identical_positions": 26, "similar_positions": 98, "identity": "5.33%" }, { "cls_id": "homologset.agr.SGD:S000006177", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1QGH4-1", "uniprot_id": "F1QGH4_DANRE", "id": "F1QGH4-1", "name": "", "aln": "--------------MSSRSFAPLSSRQENILGRAEGLR---------------QLKPGQRIVLGVLTENEQHNR----IFGQVASKYETTLQEVSKRDVSTFRASIGDSVIETATVQSVKSTSFLLPS----------------------------ELLVLDDAVQDIGSGSFMDSSMHSLADEEAAS------------------SEDVLCVSEYAEDIHRYLRECEVKY--------------RPKPGYMRKQPDITNCMRVI-LVDWLVEVG-EEYKLCSETLYLAVN----------------YLDRFLSCMSVLRGKLQLVGTAAILLAAKYEEVYPPEVDEFVYIT---DDTYTKKQLLRMEQHLLRVLAFDMTAPTIHQFLMQYSLEEHVCARTLNLALYLSELSLLEVDPFVQYLP------------SKTAAAAYCLANYTLNGALWPEN----LYAFTG----------YSLAVIGPCLKELHK----LHLGAGSRPQQAIQEKYKSSKYHGVSQLEPVETLPLP----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20438-1", "uniprot_id": "CG12_YEAST", "id": "P20438-1", "name": "G1/S-specific cyclin CLN2", "aln": "MASAEPRPRMGLVINAKPDYYPIELSNAELLSHFEMLQEYHQEISTNVIAQSCKFKPNPKLIDQQPEMNPVETRSNIITFLFELSVVTRVTNGIFFHSVRLYDRYCSKRIVLRDQAKLVVATCLWLAAKTWGGCNHIINNVVIPTGGRFYGPNPRARIPRLSELVHYCGDGQVFDESMFLQMERHILDTLNWNIYEPMINDYVLNVDENCLMQYELYENQVTYDKQCSEKRQSQLSQDSDATVDERPYQNEEEEEEDLKLKIKLINLKKFLIDVSAWQYDLLRYELFEVSHGIFSIINQFTNQDHGPFLMTPMTSESKNGEILSTLMNGIVSIPNSLMEVYKTVNGVLPFINQVKEYHLDLQRKLQIASNLNISRKLTISTPSCSFENSNSTSIPSPASSSQSHTPMRNMSSLSDNSVFSRNMEQSSPITPSMYQFGQQQSNSICGSTVSVNSLVNTNNKQRIYEQITGPNSNNATNDYIDLLNLNESNKENQNPATAHYLNGGPPKTSFINHGMFPSPTGTINSGKSSSASSLISFGMGNTQVI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .: *:. : ::*.: * *: ::**. ::: * ..* * * . : : :.* : .. :: .: * :*.: *.: .: *.: *: *.*..:*.**. :.. . .*: * * *: * ::*. * ** . .:: *:. :::* * .:*::*. :*.* *: . : :* ::. * *. : .. : :. . *** . . : :*. : :: *:: .:* : :::*: : : .: : . : . ** : . * : : .: : : * :. ::*. : .:* :** .* :. . ** :: :*..*. . *:. .* :.. :. .: .* ", "identical_positions": 64, "similar_positions": 153, "identity": "11.74%" }, { "cls_id": "homologset.agr.SGD:S000006180", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35585-1", "uniprot_id": "AP1M1_MOUSE", "id": "P35585-1", "name": "AP-1 complex subunit mu-1", "aln": "MSASAVYVLDLKGKVLICRNYRGD-VDMSEVEHFMPILMEKEEEG-MLSPILAHGGVRFMWIKHNNLYLVATS--KKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDSKILQEYITQE------GHKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIEAVNLLVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLF-------------------------------DNTGRGKSKS-VELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMVKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSVKSFPGGKEYLMRAHFGLPSVEAED-----------KEGKPPISVKFEIPYFTTSGIQVRYLKIIE-KSGYQALPWVRYITQNGD-YQLRTQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q32Q06-1", "uniprot_id": "AP1M1_RAT", "id": "Q32Q06-1", "name": "AP-1 complex subunit mu-1", "aln": "MSASAVYVLDLKGKVLICRNYRGD-VDMSEVEHFMPILMEKEEEG-MLSPILAHGGVRFMWIKHNNLYLVATS--KKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDSKILQEYITQE------GHKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIEAVNLLVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLF-------------------------------DNTGRGKSKS-VELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMVKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAED-----------KEGKPPISVKFEIPYFTTSGIQVRYLKIIE-KSGYQALPWVRYITQNGD-YQLRTQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BXS5-1", "uniprot_id": "AP1M1_HUMAN", "id": "Q9BXS5-1", "name": "AP-1 complex subunit mu-1", "aln": "MSASAVYVLDLKGKVLICRNYRGD-VDMSEVEHFMPILMEKEEEG-MLSPILAHGGVRFMWIKHNNLYLVATS--KKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDSKILQEYITQE------GHKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIESVNLLVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLF-------------------------------DNTGRGKSKS-VELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAED-----------KEGKPPISVKFEIPYFTTSGIQVRYLKIIE-KSGYQALPWVRYITQNGD-YQLRTQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O62531-1", "uniprot_id": "O62531_DROME", "id": "O62531-1", "name": "", "aln": "MSSSAIFVLDVKGKVLISRNYRGDNIDMAVIDKFMPLLMEREEEG-LITPILQTAETTFAYIKTNNLYIVSTTPRNKNVNIALVFVFLHKIAQVFVEYFKELEEESIRDNFVIIYELLDELLDFGYPQTTDSKILQEYITQE------GHKLEL-QPRIPVAVTNAVSWRSEGIKYRKNEVFLDVIESVNLLANANGNVLRSEIVGAIKMRVYLSGMPELRLGLNDKVLF-------------------------------ESTGRGKSKS-VELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIERHAHSRVEYMIKAKSQFKRRSTANNVEIVIPVPADADSPKFKTTIGSCKYAPEQNAIIWTIKSFPGGKEYLMRAHFGLPSVESEDN----------TEGKPPIQVRFEIPYFTTSGIQVRYLKIIE-KSGYQALPWVRYITQNGD-YQLRTN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9WVP1-1", "uniprot_id": "AP1M2_MOUSE", "id": "Q9WVP1-1", "name": "AP-1 complex subunit mu-2", "aln": "MSASAVFILDVKGKPLISRNYKGD-VPMTEIDHFMPLLMQREEEG-VLAPLLSHGRVHFLWIKHSNLYLVATT--LKNANASLVYSFLYKTVEVFCEYFKELEEESIRDNFVIVYDLLDELMDFGFPQTTDSKILQEYITQQ------GNKLETGKSRVPPTVTNAVSWRSEGIKYKKNEVFIDVIESVNLLVNANGSVLLSEIVGTIKLKVFLSGMPELRLGLNDRVLF-------------------------------ELTGRSKNKS-VELEDVKFHQCVRLSRFDNDRTISFIPPDGDFELMSYRLSTQVKPLIWIESVIEKFSHSRVEIMVKAKGQFKKQSVANGVEISVPVPSDADSPRFKTSVGSAKYVPEKNVVIWSIKSFPGGKEYLMRAHFGLPSVETEE-----------VEGRPPIGVKFEIPYFTVSGIQVRYMKIIE-KSGYQALPWVRYITQSGD-YQLRTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZRP6-1", "uniprot_id": "AP1M2_RAT", "id": "D3ZRP6-1", "name": "AP-1 complex subunit mu-2", "aln": "MSASAVFILDVKGKPLISRNYKGD-VPMTEIDHFMPLLMQREEEG-MLAPLLSHGRVHFLWIKHSNLYLVATT--LKNANASLVYSFLYKTVEVFCEYFKELEEESIRDNFVIVYELLDELMDFGFPQTTDSKILQEYITQQ------GNKLETGKSRVPPTVTNAVSWRSEGIKYKKNEVFIDVIESVNLLVNANGSVLLSEIVGTIKLKVFLSGMPELRLGLNDRVLF-------------------------------ELTGRSKNKS-VELEDVKFHQCVRLSRFDNDRTISFIPPDGDFELMSYRLSTQVRPRVDXESVIEKFSHSRVEIMVKAKGQFKKQSVANGVEISVPVPSDADSPRFKTSVGSAKYVPEKNVVIWSIKSFPGGKEYLMRAHFGLPSVETEE-----------VEGRPPIGVKFEIPYFTVSGIQVRYMKIIE-KSGYQALPWVRYITQSGD-YQLRTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6Q5-1", "uniprot_id": "AP1M2_HUMAN", "id": "Q9Y6Q5-1", "name": "AP-1 complex subunit mu-2", "aln": "MSASAVFILDVKGKPLISRNYKGD-VAMSKIEHFMPLLVQREEEG-ALAPLLSHGQVHFLWIKHSNLYLVATT--SKNANASLVYSFLYKTIEVFCEYFKELEEESIRDNFVIVYELLDELMDFGFPQTTDSKILQEYITQQ------SNKLETGKSRVPPTVTNAVSWRSEGIKYKKNEVFIDVIESVNLLVNANGSVLLSEIVGTIKLKVFLSGMPELRLGLNDRVLF-------------------------------ELTGRSKNKS-VELEDVKFHQCVRLSRFDNDRTISFIPPDGDFELMSYRLSTQVKPLIWIESVIEKFSHSRVEIMVKAKGQFKKQSVANGVEISVPVPSDADSPRFKTSVGSAKYVPERNVVIWSIKSFPGGKEYLMRAHFGLPSVEKEE-----------VEGRPPIGVKFEIPYFTVSGIQVRYMKIIE-KSGYQALPWVRYITQSGD-YQLRTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q618-1", "uniprot_id": "A0A8M9Q618_DANRE", "id": "A0A8M9Q618-1", "name": "", "aln": "MAASAIFILDLKGKVLICRNYMGN-IDMNVIDNFMPIMMKREEEA-ELSPVVIHGSTHFLWIKHSNLYLVAMT--KKNTNAALVYSFLYKLVEVFTEYFKSLEEESIRDNFVTVYELMDEVMDFGFPQTTDSKILLEYITQQ------GHKLEVGAPRPPATVTNAVSWRSEGIKYRKNEVFMDVIESVNLLVSATGSVLRSEILGCIKLKVVLSGMPELRLGLNDKVLF-------------------------------EITGREKTKS-VELEDVKFHQCVRLSRFENDRTISFIPPDGESELMSYRLNTTVKPLIWIESVIEKFSHSRVEIKVKARSQFKSRSTANNVSILVPVPSDADSPKFKTTTGQAKWVPEKSAVEWNIKSFPGGKEFMMRAHFGLPSVESDE-----------LEGKRPITVKFEIPYFTVSGIQVRYLKIIE-KSGYQALPWVRYITQSGD-YQLRTN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q00776-1", "uniprot_id": "AP1M1_YEAST", "id": "Q00776-1", "name": "AP-1 complex subunit mu-1-I", "aln": "-MASAVYFCDHNGKPLLSRRYRDD-IPLSAIDKFPILLSDLEEQSNLIPPCLNHNGLEYLFIQHNDLYVVAIVT-SLSANAAAIFTFLHKLVEVLSDYLKTVEEESIRDNFVIIYELLDEVMDYGIPQITETKMLKQYITQKSFKLVKSAKKKRNATRPPVALTNSVSWRPEGITHKKNEAFLDIVESINMLMTQKGQVLRSEIIGDVKVNSKLSGMPDLKLGINDKGIFSKYLDDDTNIPSASATTSDNNTETDKKPSITSSSATNKKKVNIELEDLKFHQCVRLSKFENEKIITFIPPDGKFDLMNYRLSTTIKPLIWCDVNVQVHSNSRIEIHCKAKAQIKRKSTATNVEILIPVPDDADTPTFKYSHGSLKYVPEKSAILWKIRSFPGGKEYSMSAELGLPSISNNEDGNRTMPKSNAEILKGPVQIKFQIPYFTTSGIQVRYLKINEPKLQYKSYPWVRYITQSGDDYTIRLT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**::. * :** *:.*.* .: : : :::* :: . **:. :.* : : :*: .:**:*: .. : :: **:* :*: :*:* :********** :*:*:**::*:* ** *::*:* :****: . * : .* * ::**:****.***.::***.*:*::*::*:* . .*.** ***:* :*:. *****:*:**:**: :* . :. *.* :****:*********:*:*:: *:******. :**.***.* ::* : : :: .::**:* **:.*:* :*.*..*.* :*** ***:* ** : *. *:.**.. : *.::*******: * *.:****:. :: : *: ::*:*****.*******:** * * *:: ********.** * :* ", "identical_positions": 186, "similar_positions": 144, "identity": "38.91%" }, { "cls_id": "homologset.agr.SGD:S000006183", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P14408-1", "uniprot_id": "FUMH_RAT", "id": "P14408-1", "name": "Fumarate hydratase, mitochondrial", "aln": "MNRAFCLLAR-SRRFPRVPSAGAVLS---GEAATLPRCAPNVVRMASQNSFRIEYDTFGELKVPTDKYYGAQTVRSTMNFKIGGATERMPIPVIKAFGILKRAAAEVNQEYG-LDPKIASAIMKAADEVAEGKLNDH--FPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKKPVHPNDHVNKSQSSNDTFPTAMHIAAALEVHQVLLPGLQKLHDALSAKSKEFAQVIKIGRTHTQDAVPLTLGQEFSGYVQQVQYAMERIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLGPK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97807-1", "uniprot_id": "FUMH_MOUSE", "id": "P97807-1", "name": "Fumarate hydratase, mitochondrial", "aln": "MYRALRLLAR-SRRLLRVPSAGAAVS---GEATTLPRCAPNVARMASQNSFRVEFDTFGELKVPTDKYYGAQTVRSTMNFKIGGATERMPIPVIQAFGILKRAAAEVNQEYG-LDPKIASAIMKAADEVAEGKLNDH--FPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKKPVHPNDHVNKSQSSNDTFPTAMHIAAAVEVHKVLLPGLQKLHDALSAKSKEFAQVIKIGRTHTQDAVPLTLGQEFSGYVQQVQYAMVRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALVELSGAMNTAACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDASVSFTDNCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLGPK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07954-1", "uniprot_id": "FUMH_HUMAN", "id": "P07954-1", "name": "Fumarate hydratase, mitochondrial", "aln": "MYRALRLLAR-SRPLVRAPAAALASAPGLGGAAVPSFWPPNAARMASQNSFRIEYDTFGELKVPNDKYYGAQTVRSTMNFKIGGVTERMPTPVIKAFGILKRAAAEVNQDYG-LDPKIANAIMKAADEVAEGKLNDH--FPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKIPVHPNDHVNKSQSSNDTFPTAMHIAAAIEVHEVLLPGLQKLHDALDAKSKEFAQIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLGPK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SX99-1", "uniprot_id": "FUMH_DANRE", "id": "Q7SX99-1", "name": "Fumarate hydratase, mitochondrial", "aln": "MYRSARSLHRFSASLSDLRAAQRSIK--ARNVCPAPGLRHQTVRMASSEAFRIERDTFGELKVPSDKYYGAQTVRSTMNFRIGGVTERMPIQVIRAFGILKKAAAEVNKDYG-LDPKIADAIMKAADEVESGKLDDH--FPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGKLGSKDPVHPNDHVNKSQSSNDTFPTAMHIAAAKEVHEVLLPGLQTLHDALAAKAEQFKDIIKIGRTHTQDAVPLSLGQEFGGYVQQVKYSIARVKASLPRVYELAAGGTAVGTGLNTRIGFAEKVADKVSALTGLPFVTAANKFEALAAHDALVELSGALNTVAVSMMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMIIKNVLNSARLLGDASVSFTNNCVVGIEANTERINKLMSESLMLVTALNPHIGYDKAAKIAKTAHKDGSTLKEAALKLGFLNEQQFEEWVRPHDMLGPK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08417-1", "uniprot_id": "FUMH_YEAST", "id": "P08417-1", "name": "Fumarate hydratase, mitochondrial", "aln": "MLRFTNCSCK---------------------TFVKSSYKLNIRRMNS--SFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDH--FPLVVFQTGSGTQSNMNANEVISNRAIEILGGKIGSKQ-VHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGPK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W3X5-1", "uniprot_id": "Q9W3X5_DROME", "id": "Q9W3X5-1", "name": "fumarate hydratase", "aln": "MLKQNNGLHLARRNLWVVCSG--------LRAKDCDSGGKGGKGKENG-KFRTEKDTFGELKVPADKLYGAQTMRSKLNFPIGDIGERMPMPVIQAMGILKKACAEVNKDYG-LDGKVSDAVSCACDDVISGKLYKQGHFPLVIWQTGSGTQTNMNTNEVISNAAIKMMGGELGSKKPVHPNDHVNKSQSSNDTFPTAIHISVGMELNERLVPAVTHLRDALKSKSDEFKDIIKIGRTHLMDAVPLTLGQEFSGYTQQLTNGLERIKGCLPRVYELALGGTAVGTGLNTRKGFAEKVAKRISELTCLPFVSAPNKFEALAARDAMVEVHGVLNTIAVSLMKIANDIRLLGSGPRCGLGELMLPENEPGSSIMPGKVNPTQCESMTMLCAQVMGNQVAVTIGGSNGHFELNVFKPLVVSNVLRSIRLLADGSMTFSKNCVEGLQANKERIDKIMNESLMLVTALNPHIGYDKAALIAKTAHKNKTTLKEEALKTG-ITEEQFKEWVNPKEMLGPK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W3X6-1", "uniprot_id": "Q9W3X6_DROME", "id": "Q9W3X6-1", "name": "fumarate hydratase", "aln": "-----MVLPLLQR---STLRG--------VQQMTKPWAAIGSLRLASQ-EFRVESDTFGELKVPADKYYGAQTMRSQINFPIGGATERMPKPVVQAMGILKKAAAEVNKEFG-LDSKVSEAISKAADDVISGKLYDD-HFPLVIWQTGSGTQSNMNVNEVISNRAIELLGGKLGSKTPVHPNDHVNKSQSSNDTFPTAIHISVALELNNNLKPAIKTLHDALRAKSEEFKDIIKIGRTHTMDAVPLTLGQEFSGYAQQLAYAQERIDACLPRVYELALGGTAVGTGLNTRKGFAEKCAAKIAELTSLPFVTAPNKFEALAARDAMVEVHGVLNTIAVSLMKIANDIRFLGSGPRCGLGELSLPENEPGSSIMPGKVNPTQCESLTMLSAQVMGNQVAVTIGGSNGHFELNVFKPLIVSNVLRSIRLLSDGSRTFTANCVNGIQANRENIAKIMNESLMLVTALNPHIGYDKAAKIAKTAHKNGTTLKEEAINLGYLTEQQFNDWVRPEQMLGPK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTI5-1", "uniprot_id": "Q9VTI5_DROME", "id": "Q9VTI5-1", "name": "fumarate hydratase", "aln": "MSSTKK------------------------------------------VETRQESDTLGPMEVPMDRYYGAQTMRCLINFRIGGEEERMPRQIIQAMGILKKAAAETNQEFG-LDPKLSTAISNAADDVISGKLYDEGHFPLPIWQTGSGTQSNMNSNEVIGNRAIELLGGRIGTKDPVHPNDHVNKSQSSNDTFPSAIHIAVATALTKDLRPAVTALRDSLQAKSNEWKDIIKIGRTHTQDAVPLTLGQEFSGYAQQLTNGLQRIDAVLPRVYQLALGGTAVGTGLNTRRGFAEKCVKRIAQLSGLPFVVAPNFFEALACRDAMVEVHGALNVLAVSLMKVTNDIRFLGSGPRCGLGELFLPENEPGSSIMPGKVNPTQCEAMTMICAQVMGNHVAVSVGGANGHFELNVFKPLIASNVLRSIKLLADGCISFNCNCVKGIKPNKEKLAKIVNESLMLVTALNPHIGYDKSAQIAKAAHKNGTTLKVEALNAG-ISEKDFNEWVRPEKMLGPS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IPD2-1", "uniprot_id": "Q8IPD2_DROME", "id": "Q8IPD2-1", "name": "fumarate hydratase", "aln": "MSFDQKEIFS----------------------------LMYKLARLIVPDTRVEYDSMGAVHIPLDRMFGPQTMRSLMKFPIGGVEERMPRPLIKALGIVKKSAAETNKIHC-LEEHLCDAISKACDDVISGKLYDEEHFPLVIWQDGSGEHTNMNVNEVICNRAIEILGGQMGSKEPVDPNEHVNMAQSSHDTFSTAVRIAVAMQLQETLYPSLRTFIDLLGKKSNDWMDLIKIGRTHLMDAVPLSLGQEFSGYQQQLVNGRTRLDCAMCRLYQLPMGGTSVGTKVDTKAEYSAQCIKRIAELTFLPFVESPNFFESISACDCLVELHGELNTIAASVMKIANDIRFLGSGPRCGFGELHLPENEPGSSIMPGKVNPTQCEAMSMICAQVMGNHVAVSMGGSSGHFQLNTFMPMIASNVLRSITLLGDGMKSFCTNCLEGIEPNRSKIGSIVKESLMLVTALSPHIGYERSAAIAKAAHHNGTTLEQEAILDG-IQREDFREWVQPSKMLGPE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * *::* :.:* *: :*.** *. :* **. **** :::*:*::*::.* .*: *: ::. *: *.*:* .*** .. *** ::* *** ::*** **** * **:::**.:*:* *.**:* * :***:***.:.::*:.. : : * * : : : * *:.:: .::****** **.**:*****.** **: . *: : : *. ***:*** ::*: : : ::: : * * :.* **:::. *.:** * :*. * *::*:::*** ******.* ** ******************* *::: :..*****:.*::..*:.*:*:**.* *:: *:*.* *: *. :* :*: *::.* .: .::.:********.*:***: :: :** **:. **: *: * : ::* :** * .****.", "identical_positions": 190, "similar_positions": 153, "identity": "36.96%" }, { "cls_id": "homologset.agr.SGD:S000006184", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q921I2-1", "uniprot_id": "KLDC4_MOUSE", "id": "Q921I2-1", "name": "Kelch domain-containing protein 4", "aln": "-----------------------------------------------------------------------------------------MGKKGKKEKKGRGA------EKTAAKMEKKVSKRSRKE---------EEDLEALIAHFQTLDAKKTQVTETPCPPPSPRLNASLSAHPEK--DELILFGGEYFN--GQKTFMYNELYIYSIRKDTWTKVDIPGPPPRRCAHQAVVVPQGGGQLWVFGGEFASPDGEQFYHYKDLWVLHLATKTWEQIRSTG---GPSGRSGHRMVAWKRQLILFGGFHES-ARDYIYYSDVYTFSLDTFQWSKLSPSGA-GPTPRSGCLMAVTPQGSIAIYGGYSKQRVK--KDVDKGTQHSDMFLLKPAEGG---EGKWAWTRINPSGVKPTARSGFSVAVAPNHQILVFGGVCDEEEE-ESLEGSFFSDLYIYDAAKSRWFAAQLKGPKSEKKKRRRGKAEDPEGTTEQETGGSSAPEPLEVIKEVVSEDGT-VVTIKQVLTPSGLGVQPSPKADDSASEASSTGQEPCPRSNAMLAVKHGLLYVYGGMFEAGDRQVTLSDLYCLDLHKMEEWKTLVEMD-------------PKSQEWLEESDSEEDSSSDEESEDGEDKDQE-----DSAEEGADPQHPEVARGEQFEEYLSRTEQHWLKLARSHVGPEAKEKKVLKVAQAMAKSCFDDAVQDIAQARH---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZU48-1", "uniprot_id": "D3ZU48_RAT", "id": "D3ZU48-1", "name": "", "aln": "MRPPVSHFLAFKTSHPEFAGVLGSGYILTRPETRGPADPKYWWSRLLHGTLEKRTGSDVHIARRSFLAGQNIIIHFPPVASRYPFRTCAMGKKGKKEKKGRGA------EKTAAKMEKKVSKRSRKE---------EEDLEALIAHFQTLDAKKTQVTETPCPPPSPRLNASLSAHPEK--DELILFGGEYFN--GQKTFMYNELYIYSIRKGTWTKVDIPGPPPRRCAHQAVVVPQGGGQLWIFGGEFASPDGEQFYHYKDLWVLHLATKTWEQIRSTG---GPSGRSGHRMVAWKRQLILFGGFHES-TRDYIYYSDVYTFSLDTFLWSKLSPSGP-GPTPRSGCLMAVTPQGSIAIYGGYSKQRVK--KDVDKGTQHSDMFLLKPEDGG---EDKWTWTRVNPSGVKPTVRSGFSVAVAPNHQILVFGGVCDEEEE-EHLEGSFFNDLYIYDAAKSRWFAAQLKGPKSEKKRRRRGKADDPEGATEEETGGTSAPEPLEVIKEVVSEDGT-VITIKQVLTPSGLGVQPPPKADDSASEASSTGQEPCPRSSAMLAVKHGLLYVYGGMFEAGDRQVTLSDLYCLDLHKMEEWKTLVEMD-------------PKSQEWLEESDSEEDSSSDEEGAEGGDEDQEEDSSEDSAEEGADPQHPEVAHGEQYEEYLSRTEQHWLKLARNHVGPDAKEKKVLRVAQAMAKACFDDAVPDIAQAKH---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TBB5-1", "uniprot_id": "KLDC4_HUMAN", "id": "Q8TBB5-1", "name": "Kelch domain-containing protein 4", "aln": "-----------------------------------------------------------------------------------------MGKKGKKEKKGRGA------EKTAAKMEKKVSKRSRKE---------EEDLEALIAHFQTLDAKRTQTVELPCPPPSPRLNASLSVHPEK--DELILFGGEYFN--GQKTFLYNELYVYNTRKDTWTKVDIPSPPPRRCAHQAVVVPQGGGQLWVFGGEFASPNGEQFYHYKDLWVLHLATKTWEQVKSTG---GPSGRSGHRMVAWKRQLILFGGFHES-TRDYIYYNDVYAFNLDTFTWSKLSPSGT-GPTPRSGCQMSVTPQGGIVVYGGYSKQRVK--KDVDKGTRHSDMFLLKPEDGR---EDKWVWTRMNPSGVKPTPRSGFSVAMAPNHQTLFFGGVCDEEEE-ESLSGEFFNDLYFYDATRNRWFEGQLKGPKSEKKKRRRGRKEEPEGGSRPACGGAGTQGPVQLVKEVVAEDGT-VVTIKQVLTAPGSAGQPRSEDEDSLEEAGSPAPGPCPRSNAMLAVKHGVLYVYGGMFEAGDRQVTLSDLHCLDLHRMEAWKALVEMD-------------PETQEWLEETDSEEDSE-EVEGAEGGVDDED-----SGEESGAED------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VTZ7-1", "uniprot_id": "Q9VTZ7_DROME", "id": "Q9VTZ7-1", "name": "Kelch domain-containing protein 4", "aln": "-----------------------------------------------------------------------------------------MGKKDKNKKKGKGA------EKTAMKTDKKQAARQKKML----EKLGEANIADIIQLLEAKEGKIEAISESVCPPPTPRSNFTLVCHPEK--EELIMFGGELYT--GTKTTVYNDLFFYNTKTVEWRQLKSPSGPTPRSGHQMVAVASNGGELWMFGGEHASPSQLQFHHYKDLWKFALKSRKWERIAAPN---GPSPRSGHRMTVSKKRLFIFGGFHDN-NQSYHYFNDVHIFSLESYQWLKAEIGGAIVPSPRSGCCIAASPEGKIYVWGGYSRAAMK--KEADRGVTHTDMFVLSQDKNAGDADNKYKWAPVKPGGYKPKPRSSVGCTVAANGKAYTFGGVMDVDEDDEDVHGQFGDDLLAFDLTSQTWRLQEIQTKSSSAEKKDSEESKDVEMSAVDKPVTTTTDG----IFTVTVGGPS-TSTTPFVSKIPSLFAKPKPTN------------VPSPRMNPGMCVCKGTLYIFGGIFEEDDKQLTYNDFYALDLHKLE-WKVLIPNS-------------LKGHEWE-----DSDSSSSDEECSGSEEDIS------SSSSDMDTD-----------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08979-1", "uniprot_id": "KEL3_YEAST", "id": "Q08979-1", "name": "Kelch repeat-containing protein 3", "aln": "-----------------------------------------------------------------------------------------MAKKNKKDKEAKKARAELKNQKNQKKQEKKFQKNKNKSLNGEEDDESDQDLDEILSSFSKKQIELEHVDITSVEKPSCRTHPLMFANPQHNKHELFIFGGEFTDPETKLTHFYNDLYSYSIKNNSWKKYVSQNAPLPRSSAAVAVHPS--GIALLHGGEFSSPKQSKFYHYSDTWLFDCVERKFTKLEFGGRDSSPSARSGHRIIAWKNYFILFGGFRDLGNGQTSYLNDLWCFDISTYKWTKLETNSK--PDARSGHCFIPTDN-SAILMGGYCKIIAKNNKNLMKGKILNDAWKLNLTPDP----KKWQWEKLKNFKNQPSPRVGYSFNLWKQNKSVAFGGVYDLQETEESLESVFYNDLYMFHLELNKWSKLRIKPQRQTNSKNSPATSKRKSNKDQEKELQDLLNSILAKSNLNDDDDDNDDNSTTGPNSIDDDEDNEDDSDLDNQEDITISNQLPHPRFNAATCVVGDSLFIYSGVWELGEKDYPINSFYSIDLNKLDGVKVYWEDLSAIEEAKRLGDRDSDEDEFEYEDDEEDEDDGEEEQDAGPLEGDEDEESESDDDKQAQMEIPDERSWLPHPKPFETLRAFYLREGANFLTWSISNNRNLKGKQLKTKSFELCEDRWWERRDQVTLEEERLEDTGGIIERDTTTKPSKRR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.**.*:.*:.: * :*. * :** ...* : :: :: :. : : *: * : : :*:: .**::**** * .**:*: *. :. * : . * *.. .. .. * :.***.:**. :*:**.* * : :.: :: . .** *****: . *. :::****:: . * .*: *.:.:: * * . .. * .*** : : : : ***.: * *: :* .* : *. . *: * :: :*. * . . : : : **** * :* * : . * .** :. . * .:: . .:. . . . . : . . : * ** .. .* . *:::.*::* .::: . ..::.:**:::: *. . .*: :.:.. . * * .. . . .. : ", "identical_positions": 96, "similar_positions": 167, "identity": "12.82%" }, { "cls_id": "homologset.agr.SGD:S000006185", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BY79-1", "uniprot_id": "S35G1_MOUSE", "id": "Q8BY79-1", "name": "Solute carrier family 35 member G1", "aln": "MGPPESAAELAAEAVELREPELQLADPASPG--EEHVDVEAEGAPGRGRCWPCGAWACGSRGEPEAKKKAPCPGLGLFYTVLSAFLFSVASLFVKKVQGVHAVEISAFRCVVQMLVIIPCLIYRKTGFIGPKGQRLFLFLRGVFGSSAMILMYYAFQTTSLADATVIAFSCPVFTSIFAWIFLKEKYSLWDAFFTLFAIAGVILIVRPPFIFGSDTSGMRES-----YSEHIKGTFAAIGHAVLAAI----TLVILRKMGKSVDYFLSIWYYVILGLPEAIIILFVIG--EWSLPYCGLDRLFLILIGLLGLGGQIFITKAVQIEKAGLVAIMKTMDIVFAFIFQIAFFDNVPTWWTVGGALCVVVSTTGATIRRWLQGSK-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LVD2-1", "uniprot_id": "A0ABK0LVD2_RAT", "id": "A0ABK0LVD2-1", "name": "Solute carrier family 35 member G1", "aln": "MGPPESAAELSPEAVELREPELQLADPASPG--EEHVDVEAEGAPGRGRCWPCRAWACGSRGEPEAKKTAPCPGLGLFYTVLSAFLFSVVSLLVKKVQGVHAVEISAFRCVVQMLVIIPCLIYRKTGFIGPKGQRLFLFLRGVFGSSAMILMYYAFQTTSLADATVIAFSCPVFTSIFAWIFLKEKYSLWDAFFTLFAIAGVILIVRPTFLFGSNTSGMRES-----YSEHIKGTFAAIGHAVLAAM----TLVILRKMGKSVDYFLSIWYYVILGLPETIVVLFVIG--EWSLPYCGRDRLFLILIGLVGLGAQIFITKALQIEKAGLVAIMKTMDVVFAFIFQIAFFDNVPTWWTVGGALCVVVSTTGATIRRWLQSK--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2M3R5-1", "uniprot_id": "S35G1_HUMAN", "id": "Q2M3R5-1", "name": "Solute carrier family 35 member G1", "aln": "MRPQD-----STGVAELQEPGLPLTDDAPPGATEEPAAAEAAGAPDRGRCWLCLSSPCCSRTEPEAKKKAPCPGLGLFYTLLSAFLFSVGSLFVKKVQDVHAVEISAFRCVFQMLVVIPCLIYRKTGFIGPKGQRIFLILRGVLGSTAMMLIYYAYQTMSLADATVITFSSPVFTSIFAWICLKEKYSPWDALFTVFTITGVILIVRPPFLFGSDTSGMEES-----YSGHLKGTFAAIGSAVFAAS----TLVILRKMGKSVDYFLSIWYYVVLGLVESVIILSVLG--EWSLPYCGLDRLFLIFIGLFGLGGQIFITKALQIEKAGPVAIMKTMDVVFAFIFQIIFFNNVPTWWTVGGALCVVASNVGAAIRKWYQSSK-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGN6-1", "uniprot_id": "Q9VGN6_DROME", "id": "Q9VGN6-1", "name": "EamA domain-containing protein", "aln": "----------MPENLELQQ------------------FQEGAPPPDPAPRWLER---------LQRRLGADCPYLGILLATLSSLFFSLCSVIVKGLVDVNPMELASFRFVGVLLPALPILIYTRQPVF-PEGKRVILLLRCFMGTTGLMLSFYAFRHMPLADASVIIFSTPVFVAIFARAFLKEPCTLFNVLTINMTLLGVVLITRPPFVFGDTAESEDVAG----KTYDIWGPVAAISSTLFGAN----VYILLRAL-KNLHFSVIMTNFGTIALVYTLIVCASIG--AVCWPSCGRDRWLVVVLGVFSFLGQILLTLSLQIEQAGPVAIARCADIVFAFVWQMLFFGETPTAYSLVGAVMVMGSVVLTALKKWAGTLPRESSLRKRFRLILLE----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08980-1", "uniprot_id": "YP264_YEAST", "id": "Q08980-1", "name": "Probable transport protein YPL264C", "aln": "--------------MTLQR------------------ISKDYLKPNYGLILLIVSYFFNSSMVVSTKVLENDP------LETSQSRINPLQILLVRMSITYCCTLVYMHWNKQSVPDIP---------WGPAPCRKWLILRGIMGFFGVFGMYFSLMYLSISDAVLITFMSPTLTIFLSFLLLGEPFSKLEALGSLISFSGVVLIIRPTFLFGEQTQGQQSPQDDIVETQNPKLRLIAIGVSLLGVCGLSSVYIIIRYIGNKAHAIMSVSYFSLVTTVVAALGVLLIPSMSLQLPHSWKQWGLFLNLGISGFIHQILLTMGIQRERAGRGSLMTYTQVIYAVFWDVVLFHHWPNIWTWCGMAVIVSSTIWVINMRASKQNVVATAELLSTSDFELDDLED", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:. : *. . . : * * :. .::: : . : :: : :* * * *:** .:* .:: ::: .::** :* * *.:. ::: * * : :.: ::: **:** **.*:**. :.. . : . . **. :::.. . :::* : :. . : : : : : : : * . : :.: :*: .: **::* .:* *:** :: ::::*..::: :* . *. :: * :: * . : ", "identical_positions": 44, "similar_positions": 112, "identity": "11.0%" }, { "cls_id": "homologset.agr.SGD:S000006186", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TBB6-1", "uniprot_id": "S7A14_HUMAN", "id": "Q8TBB6-1", "name": "Solute carrier family 7 member 14", "aln": "----MSGFFTSLDPRR-VQW----GAAWYAMHSRILRTKPVESMLEGTGTTTAHGTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAVWVFIMIAGLFFINGKYWAEGQ-FLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVKFLSEEHTKKKEGILADCEKEACSPVSEGDEFSGPATNTCGAKNLPSLGD-------NEMLIGKSDKSTYNVNHPN--YGTVDMTTGIEADESENIYLIKLKKLIGPHYYTMRIRLGLPGKMD--RPTAATGHTVTICVLLLFILMFIFCSFIIFGSDYISEQSWWAILLVVLMVLLISTLVFVILQQPENPKKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVWCFVGLLIYFGYGIWNSTLEIS---------------------------------AREEALHQSTYQRYDVDDPFS---VEEGFSYATEGESQEDWGGPTED---KGFYYQQMSDAKANGRTSSKAKSKSKHKQNSEALIANDELDYSPE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZSU3-1", "uniprot_id": "D3ZSU3_RAT", "id": "D3ZSU3-1", "name": "", "aln": "----MSGFLSSLDPRR-VQW----GAAWYAMHSRILRTKPVESMLEGTGATSAHGTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMVDTVGTLNGLGKGEESYPDLLALVIAVIVTIIVALGVKNSVGFNNVLNVLNLAVWVFIMIAGLFFVNGKYWAEGQ-FLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSMILTLMVPYYAIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLSLLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVKFLSEEHTKKKEGILADCEKETCSPVSEGEEFSSPATNTCGAKNLPSLGD-------NEMLIGKSDKSAYNVNHPN--YGTVDMTTGIEADESENIYLIKLKKLIGPRYYTMRIRLGLPGKMD--RPTAATGHTVTICVLLLFILMFIFCSFVIFGSEYISGQSWWAILLVVLMLLLITVLVFVILQQPENPKKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVWCFVGMLIYFGYGIWNSTLEIS---------------------------------AREQALHQSTYQRYDVDDPFS---VEEGFSYATEGESQEDWGGPAED---KGFYYQQMSDAKANSRTSSKAKSKSKHKQNSEALIENDELDCSPE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VWD3-1", "uniprot_id": "Q9VWD3_DROME", "id": "Q9VWD3-1", "name": "Cationic amino acid transporter C-terminal domain-containing protein", "aln": "--MKPSDLLLVLEKVK-FRVPLPPGVSSTTLLPKLIRTKDVKQLQDGN--AQPQKPKLTKCLNTLDLTSLGIGSCCGTGMYLVAGMVAQKIAGPGVIISFIIAAIASIFSGACYAEFGVRVPHTSGSAYMYSYVAVGEFVAFIIGWNMILEYLIGTSACACALSSSFDSLTGNAIARTISESIGTIFGKP------PDFIAFGITLLMTCVLAMGASKSVIFNHSLNAVNLATWVFVMAAGLFYVDTKTWSEHQGFLPYGWSGVFSGAATCFYAFIGFDIIATTGEEAHNPQKSIPKAIVGSLVVVLIAYVSVSLVLTLVVPYDHINTGAALVQMWSYVNAPKCRAVVAIGATAGLSVAMFGSMFPMPRVIYAMAQDGLIFRQLSQLWHRTNVPGLATIGSGLAAALVALTVRLEILVEMMSIGTLLAYTLVSTCVLVLRYQPHS--TSLVELLPAQLRTPVAHGTASDSRSHVTPA-EVLEVPGKLTIKRVTRGMSDSDDSFIDDSPEGFLGGRDDQFLVSDRSENKFYGSVHGAPTGPTGQATAFDAMGLNFVTRKIHDYAYLCPGFFPWINPGQATAESGMYVTKLVGIMFGLIFFLDLFAAIG---WSGG--LAAFIYFILFIGIFVILLIISRQPQNRYALAFLTPGLPFIPAIAITVNIYLIFKLSILTLVRFTVWMSLGFIMYFYYGITHSSLEQASDDLELHVDYSKNVEEKAVWDQQSYNQTHEPVWASKEVKQPSTEQRYNYGKTTSSSSSAQGSSRSGQGSAPEKPAGRSTAGLNRPVPPPPIAGQAKGSGSGSGPPMERQYTGQFSMFVDEGQFPTWDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53388-1", "uniprot_id": "DIP5_YEAST", "id": "P53388-1", "name": "Dicarboxylic amino acid permease", "aln": "MKMPLKKMFTSTSPRNSSSLDSDHDAYYSKQNPDNFPVKEQEIYNIDLEENNVSSRSSTSTSPSARDDSFAVPDGKDENTRLRKDLKARHIS---------MIAIGGSLGTGLLIGTGTALLTGGPVAMLIAYAFVGLLVFYTMACLGEMASYIPLDGFTSYASRYVDPALGFAIG----------------------YTYLFKYFILPPNQLTAAALVIQYWISRDRVNPGVWITIFLVVIVAIN----------------------VVGVKFFGEFEFWLSS--------------------FKVMVMLGLILLLFIIMLGGGPNHDRLGFRYWRDPGAFKEYSTAITGGKGKFVS--------------------FVAVFVYSLFSYTGIELTGIVCSEAENPRKSVPKAIKLTVYRIIVFYLCTVFLLGMCVAYN--------------DPRLLSTKGKSMSAAASPFVVAIQNSGIEVLPHIFNACVLVFVFSACN-------SDLYVSSRNLYALAIDGKAP------KIFAKTSRWGVPYNALILSVLFCG-LAYMNVSSGSAKIFN-----------------------YFVNVVSMFG-----------ILSWITILIVYIYFDKACRAQGIDKSKFAYVAPGQRYGAYFALFFCILIALIKNFTVFLGHKFDYKTFITGYIGLPVYIISWAGYK------------------------------LIYKTKVIKSTDVDLYTFKEIYD----------------REEEEGRMKD------------QEKEERLKSNGKNMEWFYEKFLGNIF----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: . . .. . : .* : . . :. : *:.: . . . : .: *:.:: : *:.. :. *. : * :*. ** :* : :. : * . :. * .*. . :*. : .::. .. : : : :* ..*: :: . :. :: .. . * *:: :: . : . :.: ::* ::: : .. : . .. *. . : :: : : * . : * . :: :. : : : * : *:. ** . . * . : . *. : . : . : . : : . : *. : : * :: ::. . :* : . :.: : * : :.:::* : . :*: . * : : . . : . . : *: : : :. : : : * . . *. * ... : : :. ", "identical_positions": 39, "similar_positions": 187, "identity": "4.69%" }, { "cls_id": "homologset.agr.SGD:S000006187", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D0D4-1", "uniprot_id": "DIM1_MOUSE", "id": "Q9D0D4-1", "name": "Dimethyladenosine transferase", "aln": "MPKAKSAASSRRRDRQEQRRELKRAGGLMFNTGIGQHILKNPLIVNSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPLASKLQVLVGDVLKSDLPFFDACVANLPYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVQNTVIPEDFS-----IADKIQQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G2S6-1", "uniprot_id": "A0A8I6G2S6_RAT", "id": "A0A8I6G2S6-1", "name": "rRNA adenine N(6)-methyltransferase", "aln": "MPKAKSAASSRRRDRQEQRGELKRAGGLMFNTGIGQHILKNPLIVNSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPLASKLQVLVGDVLKSDLPFFDACVANLPYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVQNTVIPEDFS-----IADKIQQILTNTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UNQ2-1", "uniprot_id": "DIM1_HUMAN", "id": "Q9UNQ2-1", "name": "Dimethyladenosine transferase", "aln": "MPKVKSGAIGRRRGRQEQRRELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDFS-----IADKIQQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VAQ5-1", "uniprot_id": "DIM1_DROME", "id": "Q9VAQ5-1", "name": "Probable dimethyladenosine transferase", "aln": "MPKVTKEKKSRIHNDVQKQ-------GIVFNKDFGQHILKNPLVITTMLEKAALRATDVVLEIGPGTGNMTVRMLERAKKVIACEIDTRLAAELQKRVQATPLQPKLQVLIGDFLKAELPFFDLCIANVPYQISSPLIFKLLLHRPLFRCAVLMFQREFAERLVAKPGDKLYCRLSINTQLLARVDMLMKVGKNNFRPPPKVESSVVRLEPKNPPPPVNFTEWDGLTRIAFLRKNKTLAATFKVTSVLEMLEKNYKLYRSLRNEPIEDDFK-----MQDKVISILEEQDMAAKRARSMDIDDFMRLLLAFNSAGIHFN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41819-1", "uniprot_id": "DIM1_YEAST", "id": "P41819-1", "name": "Dimethyladenosine transferase", "aln": "MGKAAKKKYSGATSSKQVSAEKHLSSVFKFNTDLGQHILKNPLVAQGIVDKAQIRPSDVVLEVGPGTGNLTVRILEQAKNVVAVEMDPRMAAELTKRVRGTPVEKKLEIMLGDFMKTELPYFDICISNTPYQISSPLVFKLINQPRPPRVSILMFQREFALRLLARPGDSLYCRLSANVQMWANVTHIMKVGKNNFRPPPQVESSVVRLEIKNPRPQVDYNEWDGLLRIVFVRKNRTISAGFKSTTVMDILEKNYKTFLAMNNEMVDDTKGSMHDVVKEKIDTVLKETDLGDKRAGKCDQNDFLRLLYAFHQVGIHFS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *. . . . : : **..:*********: :::** :*.:*****:******:**::**:**:*:* *:*.*:.*** ***:.**: **::::**.:*::**:** *::* *******::***: : * ::******** **:*:***.****** *.*: *.* :************:*******:* *** * ::: ***** **.*:***:*::* ** ::* ::*****: . ::.* : : : :*: :* . .:. *** . * :**:*** .*: ****.", "identical_positions": 154, "similar_positions": 89, "identity": "48.43%" }, { "cls_id": "homologset.agr.SGD:S000006189", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10686-1", "uniprot_id": "PLCG1_RAT", "id": "P10686-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------MAGVGTPCANGCGPSAPSEAEV----------------------------------LHLCRSLEVGTVMTLFYSKKSQ-----RPERKTFQVKLETRQITWSRGADK-----IEGSIDIREIKEIRPGKTSRDFDRYQE------DPAFRPDQSHCFVILYGM-EFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAA--------------TPLQIERWLRKQFYSVD----------RNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDFEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLETN---TLRTGERPELCQVSLSEFQQFLLEYQGELWAVDRL------QVQEFMLSFLRDPLREIEEPYFFLDELVTFLFSKENSVWNSQLDAVCPETMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWD--GPDGMPVIYHGH---------------TLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCS-IAQQRNMAQHFRKVLGDTLLTKPVDIAADG-----LPSPNQLKRKILIKHKKLAEGSAYEEVPTSV------------------MYSENDISNSIKNGILYLEDPVNHEWYP------------------------------HYFVLTSSKIYYS---------------EETSSDQGNEDEEEPK--------------------------------------EASGSTELHSSEKWFHGKLGAGRDGRHIAERLLT--------------------EYCIETGAPDGSFLVRESET--FVGDYTLSFWRNGKVQHCRIHSRQDAGTPKF---FLTDNLVFDSLYDLITHYQQVPLRCNE-------FEMRLSEP---VPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR------KRNEPNSYAISFRAEG-------KIKHCRVQQEGQTVML---GNSE-FDSLVDLISYYEKHPLYRKMKLRYPINEEAL--EKIGTAEPDYGALYEGRNPGFYVEANPMP--TFKCAVKALFDYKAQREDELT--------------------FTKSAIIQNVEKQDGGWWRGDYGGKKQLWFPSNYVEEMINPAILEPER--------------------EHLDENSPLGDLLRGVLDVPACQIAIR--------------PEGKNNRLFVFSISMPS-VAQWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVN--------------------------------------------------------------------------------------------------------------KAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMAGGHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCVICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAKENGDLSPFSGTSLRERASDASSQLFHVRAREGSFEARYQQPFEDFRISQEHLADHFDSRERRAP----RRTRVNGD---NRL----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62077-1", "uniprot_id": "PLCG1_MOUSE", "id": "Q62077-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------MAGVATPCANGCGPGAPSEAEV----------------------------------LHLCRSLEVGTVMTLFYSKKSQ-----RPERKTFQVKLETRQITWSRGADK-----IEGSIDIREIKEIRPGKTSRDFDRYQE------DPAFRPDQSHCFVILYGM-EFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAA--------------TPLQIERWLRKQFYSVD----------RNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLETN---ALRTGERPEHCQVSLSEFQQFLLEYQGELWAVDRL------QVQEFMLSFLRDPLREIEEPYFFLDELVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWD--GPDGMPVIYHGH---------------TLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCS-IAQQRNMAQHFRKVLGDTLLTKPVDIAADG-----LPSPNQLRRKILIKHKKLAEGSAYEEVPTSV------------------MYSENDISNSIKNGILYLEDPVNHEWYP------------------------------HYFVLTSSKIYYS---------------EETSSDQGNEDEEEPK--------------------------------------EASSSTELHSSEKWFHGKLGAGRDGRHIAERLLT--------------------EYCIETGAPDGSFLVRESET--FVGDYTLSFWRNGKVQHCRIHSRQDAGTPKF---FLTDNLVFDSLYDLITHYQQVPLRCNE-------FEMRLSEP---VPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR------KRNEPNSYAISFRAEG-------KIKHCRVQQEGQTVML---GNSE-FDSLVDLISYYEKHPLYRKMKLRYPINEEAL--EKIGTAEPDYGALYEGRNPGFYVEANPMP--TFKCAVKALFDYKAQREDELT--------------------FTKSAIIQNVEKQDGGWWRGDYGGKKQLWFPSNYVEEMINPAVLEPER--------------------EHLDENSPLGDLLRGVLDVPACQIAIR--------------PEGKNNRLFVFSISMPS-VAQWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVN--------------------------------------------------------------------------------------------------------------KAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMAGGHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCVICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAKENGDLSPFSGISLRERASDASSQLFHVRAREGSFEARYQQPFEDFRISQEHLADHFDSRERSTSDGPSSATNLIEDPLHDKLWKCSL-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19174-1", "uniprot_id": "PLCG1_HUMAN", "id": "P19174-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------MAGAASPCANGCGPGAPSDAEV----------------------------------LHLCRSLEVGTVMTLFYSKKSQ-----RPERKTFQVKLETRQITWSRGADK-----IEGAIDIREIKEIRPGKTSRDFDRYQE------DPAFRPDQSHCFVILYGM-EFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAP--------------TPLQIERWLRKQFYSVD----------RNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEAS---TLRAGERPELCRVSLPEFQQFLLDYQGELWAVDRL------QVQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWD--GPDGMPVIYHGH---------------TLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCS-IAQQRNMAQYFKKVLGDTLLTKPVEISADG-----LPSPNQLKRKILIKHKKLAEGSAYEEVPTSM------------------MYSENDISNSIKNGILYLEDPVNHEWYP------------------------------HYFVLTSSKIYYS---------------EETSSDQGNEDEEEPK--------------------------------------EVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLT--------------------EYCIETGAPDGSFLVRESET--FVGDYTLSFWRNGKVQHCRIHSRQDAGTPKF---FLTDNLVFDSLYDLITHYQQVPLRCNE-------FEMRLSEP---VPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR------KRNEPNSYAISFRAEG-------KIKHCRVQQEGQTVML---GNSE-FDSLVDLISYYEKHPLYRKMKLRYPINEEAL--EKIGTAEPDYGALYEGRNPGFYVEANPMP--TFKCAVKALFDYKAQREDELT--------------------FIKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVNPVALEPER--------------------EHLDENSPLGDLLRGVLDVPACQIAIR--------------PEGKNNRLFVFSISMAS-VAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVN--------------------------------------------------------------------------------------------------------------KAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAKENGDLSPFSGTSLRERGSDASGQLFHGRAREGSFESRYQQPFEDFRISQEHLADHFDSRERRAP----RRTRVNGD---NRL----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CIH5-1", "uniprot_id": "PLCG2_MOUSE", "id": "Q8CIH5-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MTTMVN---VDTLPEYEK----------------------------------SQIKRALELGTVMTVFNARKS------TPERRTVQMIMETRQVAWSKTADK-----IEGFLDIMEIKEIRPGKNSKDFERAK---------AVRHKAECCFTILYGT-QFVLSTLSLATDSKEDAVKWLSGLKILHQEAMSAS--------------TPTMIESWLRKQIYSVD----------QTRRNSISLRELKTILPLVNFKVSGIKFLKDKLVEIGAQKDELSFEQFHLFYKKLMFDQQKSILDEFKKDSSVFILGNTDRPDASAVYLQDFQRFLLHEQQELWAQDLN------KVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRAGCRCIELDCWD--GPDGKPIIYHGW---------------TRTTKIKFDDVVQAIRDHAFVTSSFPVILSIEEHCS-VEQQRHMAKVFKEVLGDMLLTKPTEASADQ-----LPSPSQLREKIIIKHKKLGP---KGDVDVNV------------------EDKKDEHK---PQGELYMWDSIDQKWTR------------------------------HYCAIADAKLSFG---------------DDIEQA----VEEEPV--------------------------------------QDTPPTELHFGEKWFHKKVES----RTSAEKLLQ--------------------EYCAETGAKDGTFLVRESET--FPNDYTLSFWRSGRVQHCRIRSTMENGVMKY---YLTDNLTFNSIYALIQHYREAHLRCAE-------FELRLTDP---VPNPNPHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIR------KREGTNSYAITFRARG-------KVKHCRINRDGRHFVL---GTSAYFESLVELVSYYEKHALYRKMRLRYPVTPELL--ERYN-MERDINSLYDVSR--MYVDPSEINPSMPQRTVKALYDYKAKRSDELT--------------------FCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISAGDAEEMEK--------------------QIIEDN-PLGSLCKGILDLNTYNVVKA--------------PQGKNQKAFVFILEPKK-QGDPPVEFATDRVEELFEWFQSIREITWKMDTKENNMKYWERNQSIAIELSDLVVYCKPTSKTKDHL--ENPDFREIRSFVETKADSIV---------------------------------------------------------------------------------------------------------------RQKPVDLLRYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKYMQMNHALFSLNGRTGYVLQPESMRSEKYDPMPLESQR-KILMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDSNKFKTTVVNDNGLSPVWAP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TQEKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCRQLRRRQEELNNQLFLYDTHQNLRGANRDALVKEFNVNENQLQLYQEKCNRRLR-----EKRVSNS----RFYS--------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24135-1", "uniprot_id": "PLCG2_RAT", "id": "P24135-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MTTMVN---VDTLPEYEK----------------------------------SQIKRALELGTVMTVFSARKS------TPERRTVQMIMETRQVAWSKTADK-----IEGFLDIMEIKEIRPGKNSKDFERAK---------AVRHKADCCFTIFYGT-QFVLSTLSLATDSKEDAVKWLSGLKILHQEAMNAS--------------TPTMIESWLRKQIYSVD----------QTRRNSISLRELKTILPLVNFKVSGIKFLKDKLVEIGAQKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASAVYLQDFQRFLLHEQQELWAQDLN------KVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRAGCRCIELDCWD--GPDGKPIIYHGW---------------TRTTKIKFDDVVQAIRDHAFVTSSFPVILSIEEHCS-VEQQRHMAKVFKEVLGDLLLTKPTEASADQ-----LPSPSQLREKIIIKHKKLGP---RGDVDVNV------------------EDKKDEHK---TQGELYMWDSIDQKWTR------------------------------HYCAIADAKLSFS---------------DDIEQT----VEEDPV--------------------------------------QDTPPTELHFGEKWFHKKVES----RTSAEKLLQ--------------------EYCAETGAKDGTFLVRESET--FPNDYTLSFWRSGRVQHCRIRSTMEGGVMKY---YLTDNLTFNSIYALIQHYREAHLRCAE-------FELRLTDP---VPNPNPHESKPWYYDRLSRGEAEDMLMRIPRDGAFLIR------KREGTDSYAITFRARG-------KVKHCRINRDGRHFVL---GTSAYFESLVELVSYYEKHALYRKMRLRYPVTPELL--ERYN-MERDINSLYDVSR--MYVDPSEINPSMPQRTVKALYDYKAKRSDELT--------------------FCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISAGDAEEMEK--------------------QIIEDN-PLGSLCRGILDLNTYNVVKA--------------PQGKNQKAFVFILEPKK-QGDPPVEFATDRVEELFEWFQSIREITWKIDTKENNMKYWERNQSIAIELSDLVVYCKPTSKTKDHL--ENPDFREIRSFVETKADSIV---------------------------------------------------------------------------------------------------------------RQKPVDLLRYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKYMQMNHALFSLNGRTGYVLQPESMRSEKYDPMPPESQR-KILMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDSNKFKTTVVNDNGLSPVWAP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TQEKVTFEIYDPNLAFLRFLVYEEDMFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCRQLRRRQEELNNQLFLYDTHQNLRGANRDALVKEFNVNENQLRLYQEKCNRRLR-----EKRVSNS----RFYS--------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16885-1", "uniprot_id": "PLCG2_HUMAN", "id": "P16885-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MSTTVN---VDSLAEYEK----------------------------------SQIKRALELGTVMTVFSFRKS------TPERRTVQVIMETRQVAWSKTADK-----IEGFLDIMEIKEIRPGKNSKDFERAK---------AVRQKEDCCFTILYGT-QFVLSTLSLAADSKEDAVNWLSGLKILHQEAMNAS--------------TPTIIESWLRKQIYSVD----------QTRRNSISLRELKTILPLINFKVSSAKFLKDKFVEIGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASAVYLHDFQRFLIHEQQEHWAQDLN------KVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDCWD--GPDGKPVIYHGW---------------TRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCS-VEQQRHMAKAFKEVFGDLLLTKPTEASADQ-----LPSPSQLREKIIIKHKKLGP---RGDVDVNM------------------EDKKDEHK---QQGELYMWDSIDQKWTR------------------------------HYCAIADAKLSFS---------------DDIEQT----MEEEVP--------------------------------------QDIPPTELHFGEKWFHKKVEK----RTSAEKLLQ--------------------EYCMETGGKDGTFLVRESET--FPNDYTLSFWRSGRVQHCRIRSTMEGGTLKY---YLTDNLTFSSIYALIQHYRETHLRCAE-------FELRLTDP---VPNPNPHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIR------KREGSDSYAITFRARG-------KVKHCRINRDGRHFVL---GTSAYFESLVELVSYYEKHSLYRKMRLRYPVTPELL--ERYN-MERDINSLYDVSR--MYVDPSEINPSMPQRTVKALYDYKAKRSDELS--------------------FCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISTADFEELEK--------------------QIIEDN-PLGSLCRGILDLNTYNVVKA--------------PQGKNQKSFVFILEPKQ-QGDPPVEFATDRVEELFEWFQSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNL--ENPDFREIRSFVETKADSII---------------------------------------------------------------------------------------------------------------RQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKYMQMNHALFSLNGRTGYVLQPESMRTEKYDPMPPESQR-KILMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDNNKFKTTVVNDNGLSPIWAP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TQEKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKAVKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCRQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFSVNENQLQLYQEKCNKRLR-----EKRVSNS----KFYS--------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXH3-1", "uniprot_id": "Q9VXH3_DROME", "id": "Q9VXH3-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma", "aln": "--------------------------------------------------------------------------------------------------------------------------------------MSCFS--AMSAPLLGEM----------------------------------EQTIGMLERGTIVTKLYGKQR------RPDRRHLMLIRETRQLLWATVATQTPRTDYEGAIQLREIREIRVGKHSKEFRLFAD------D-CQRFESSKCFVILHGN-HFKLKSFSVVALSEIEADNWVRGLRYMVKDTLGAP--------------YPLQIDRWLRREYYQIENVNTHSAKATEQSPAQVTIKDFKLFLAGVSCKMTTGKFMEHFTEDVR-RKHDLKFDDFSRLYQKLLLPNG---FASVLSGSGVANFPYSE--DQQVVRPAELKQFLETEQRDVSASEISS----AAIASFIRDFVQDVERDVQEPYLTFPEFVDFLFSKQNDLWNSKYDQVFMD-MNLPLSSYWIASSHNTYLTGDQFSSESSCEAYARALRMGCRCIELDCWN--GPDNLPYIFHGH---------------TITSKIKFMDVIKTIKDHAFTSSEYPVILSIEQNCS-LEQQRNMAQALIEVFGDMLLTQPCDRNEQH-----LPSPYQLRRKIILKHKKLPQFDDIANGISSTGSLGHRSSLGGAGGGAHGENDGENVRKVFKEGLLYFKDPVDKSWNL------------------------------YQFVLTHQELIYS---------------SEINESRNGNSEDDDFG---------------------LSSSCSLNSNMQQKQKDTSANDELHFGENWFHGKLEGG---RKEADDLLK--------------------KYKHFG---DGTFLVRESAT--FVGDYSLSFWRRNRPNHCRIKLKHENGSIKY---YLVENFVFDSLYSLIVYYRKNMLRSSE-------FSIILKEP---VPQPKKHEDQEWFHPNTTKEQAEQGLYRLEIG-SFLVRP-----SVQSINAFVISFTINR-------KIKHCRIMQEGRLYGI---DTMN-FESLVSLINYYTRNPLYRNVKLSHPVSQELLRQALAEAAQGDHSGGHDDNGASNYMGSNLEEN----VTCKALYSYKANKPDELS--------------------FPKHAIITNVQRDNSMWWIGDYGGMIKKHLPANYVKVIDS---TTEDY--------------------NSLNEE---GTDGR-TDSIEIFGAVAS--------------LFESNDPGIIFKLQIQTPTMQNPFVIGFDNQETAYEWIKAIQEAALIASQLASERRKKERTARVAKEMSDLIIYFRSVPFREHSW-----IFQEMSSFPETKAEKQFF--------------------------------------------------------------------------------------------------------------QQNTQLFLSYHRNQISRVYPKGQRLDSSNFNPMPFWNVGSQMIALNYQTGDKAMQLNQAKFRNNGQCGYILKPSFMKSDSFNPNNPLCDG-LSEVKVSIRLIAARHLFRGGK-SNNPQIVVELIGASFDTGVKYRTKVNENGFNPVWN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ESCEFNVRNPQFAILRFEVQDEDMFAETHFIAQACYPLTCIRQGYRSVILRNKFSEELELSSLLINIKIANVTAP------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8K3R3-1", "uniprot_id": "PLCD4_MOUSE", "id": "Q8K3R3-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MTSQIQDLLAT-----------------------------------DQDLLLMQEGTMMRKVRTKS-------WKKLRYFRLQNDGMTVWHGSQPE----SMPKPTFSISDVERIRKGQDSELLRY---------LVE-EFPLEQGFTVVFHG---RRPNLDLVANSVEEAQIWMRGLQLLVDLVASMD--------------HQEQMDQMLNEWFQQADR-------NQDGRMSFREAQRLLLLMNVEMDEEYAFSLFQEADVT---QSDDLGSEEFVQFYKALTKRTEIEEIFED----------FSSDKQ--KLTLLEFVDFLRKEQKEKDHAPDLA--------LELIDRYEPSENGRLLHVLSKDGFLKYLCSKDGNIFNSDCLPIYQD-MTQPLSHYYINSSHNTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDTW--DGPDGEPVVYHGH---------------TLTSRILFKDVLATLAQYAFQSSDYPLILSLENHCT-WEQQRTMAHHLTEILGEQLLRNTLEGLLVD----SMPSPEQLRGKILVKGKKLRTIEVDKEEEEEEEEEELEKDEGPDLDP--------------------------------------------------------------ASPELDTQPQP----------------ETQGQAAGNKKERKKKVMKCPMSCLLICGHVMAQAPSSIPESILLSKQFLLLSSTTIMCPDLSALVVYLRTVPFCSFTH-SKENYHI---------------------YDISSFSESKAKNLIKEAGN--EFVQHNARQLCRVYPSGLRTDSSNFNPQEHWNVGCQMVAMNMQTAGSAMDICDGLFRQNGG-------SGYVLKPE---FLRDTQSSFNPER--PISLYKAQILVVQVISGQQLPKVD---KTKETTVVDPLVKVELYG-------VPEDTKEQETSHVEN------NGINPYWGET--FYFRLQVPELAMLRFVVKD-YSRKSRNNFIGQYTLPWTCMKQG--YRHVSLLSRDGTSLNPASIFVYTCMQEDLD--------------------MDEP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62711-1", "uniprot_id": "PLCD4_RAT", "id": "Q62711-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MASQIQKLLTT-----------------------------------NQDLLLMQKGTMMRKVRTKS-------WKKLRYFRLQDDGMTVWHGRHLE----SISKPTFSISDVERIRKGQDSELLRY---------LVE-EFPLEQGFTIVFNG---RRPNLDLVANSVEEAQTWMRGLQLLVDLVARMN--------------YQEQLDQMLREWFQQADR-------NQDSRMSFREAQRLLLLMNVEMDEEYAFSLFQEADVS---QSNTLDSEEFVQFYKALTKRTEIEELFEN----------FSSDKQ--KLTLLEFVDFLREEQKESDHSSDLA--------LKLIDRYEPSENGRLLRVLSKDGFLSYLCSADGNIFNPDCLPIYQD-MTQPLSHYYINSSHNTYLLGDQFCGQSSVEGYIRALKRGCRCVEVDTW--DGPDGEPVVYHGR---------------TLTSRILFKDVLATLAQYAFQSSDYPLILSLDNHCT-WEQQKTMAHHLIAILGEQLLSTTLEEQLID----IMPSPEQLRGKILVKGKKLRTIEV---VESDKEEEELEKDEGSDLDP--------------------------------------------------------------ASAELDMQSQP----------------ESQEQASGNKSKNKK--------------------------------KFLLQSSTTILCPDLSALVVYLRTAPFCSFTH-SKENYHI---------------------YDISSFSESKAKNLIREAGN--EFVQHNARQLCRVYPSGLRTDSSNYNPQEHWNVGCQMVAMNMQTAGSAMDICDGLFRQNGG-------SGYVLKPE---FLRDTQSSFNPMK--PVSLYKAQILVVQVISGQRLPKVD---KTKETTVVDPLVRVELYG-------VPEDTKQQETSYVEN------NGINPYWGET--FYFQIQVPELAMLRFVVKD-YSRTSRNNFIGQYTLPWTCMKHG--YRHVSLLSKDGTSLHPASIFVYTCMQEDLD--------------------MDEP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BRC7-1", "uniprot_id": "PLCD4_HUMAN", "id": "Q9BRC7-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MASLLQDQLTT-----------------------------------DQDLLLMQEGMPMRKVRSKS-------WKKLRYFRLQNDGMTVWHARQAR----GSAKPSFSISDVETIRNGHDSELLRS---------LAE-ELPLEQGFTIVFHG---RRSNLDLMANSVEEAQIWMRGLQLLVDLVTSMD--------------HQERLDQWLSDWFQRGDK-------NQDGKMSFQEVQRLLHLMNVEMDQEYAFSLFQAADTS---QSGTLEGEEFVQFYKALTKRAEVQELFES----------FSADGQ--KLTLLEFLDFLQEEQKERDCTSELA--------LELIDRYEPSDSGKLRHVLSMDGFLSYLCSKDGDIFNPACLPIYQD-MTQPLNHYFICSSHNTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDVW--DGPSGEPVVYHGH---------------TLTSRILFKDVVATVAQYAFQTSDYPVILSLETHCS-WEQQQTMARHLTEILGEQLLSTTLDGVLPT----QLPSPEELRRKILVKGKKL-TLEEDLEYEEEEAEPELEESE--------------------------------------------------------------------LALESQFETEP----------------EPQEQNLQNKDKKKK--------------------------------------SKPILCPALSSLVIYLKSVSFRSFTH-SKEHYHF---------------------YEISSFSETKAKRLIKEAGN--EFVQHNTWQLSRVYPSGLRTDSSNYNPQELWNAGCQMVAMNMQTAGLEMDICDGHFRQNGG-------CGYVLKPD---FLRDIQSSFHPEK--PISPFKAQTLLIQVISGQQLPKVD---KTKEGSIVDPLVKVQIFG-------VRLDTARQETNYVEN------NGFNPYWGQT--LCFRVLVPELAMLRFVVMD-YDWKSRNDFIGQYTLPWTCMQQG--YRHIHLLSKDGISLRPASIFVYICIQEGLE--------------------GDES-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R3B1-1", "uniprot_id": "PLCD1_MOUSE", "id": "Q8R3B1-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MDSGRDFLTLHGLQD-----------------------------------DPDLQALLKGSQLLKVKSSS-------WRRERFYKLQEDCKTIWQESRKV--MRSPESQLFSIEDIQEVRMGHRTEGLEK---------FAR-DIPEDRCFSIVFKD---QRNTLDLIAPSPADVQHWVQGLRKIIDRSGSMD--------------QRQKLQHWIHSCLRKADK-------NKDNKMNFKEVKDFLKELNVQVDDSYARKIFRECDHS---QTDSLEDEEIETFYRMLTQRAEIDRAFAE----------AAGSAE--TLSVEKLVTFLQHQQREEEAGPALA--------LSLIERYEPSETAKAQRQMTKDGFLMYLLSADGNAFSLAHRRVYQD-MNQPLSHYLVSSSHNTYLLEDQLTGPSSTEAYIRALCKGCRCLELDCW--DGPNQEPIIYHGY---------------TFTSKILFCDVLRAIRDYAFKASPYPVILSLENHCS-LEQQRVMAHHLRAILGPMLLDQPL-DGVTT----SLPSPEQLKEKILLKGKKLGGLLPAGGENGPEATDVSDEDE-----------------------------------------------------------------------AAEMEDEA----------------VRSQVQHKPKEDKLK------------------------------------------LVPELSDMVIYCKSVHFGGFSSPSTSGQAF---------------------YEMASFSESRALRLLQESGN--SFVRHNVGHLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYLGCFQDNGG-------CGYVLKPA---FLRDPDTTFNSRALTQGPWWAPKKLRVWIISGQQLPKVN---KNK-NSIVDPKVIVEIHG-------VGQDVASRQTAVITN------NGFNPRWDTE--FEFVVAVPDLALVRFMVED-YDSSSKNDFIGQSTIPWNSLKQG--YRHVHLLSKNGDLHPSATLFVKISIQD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10688-1", "uniprot_id": "PLCD1_RAT", "id": "P10688-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MDSGRDFLTLHGLQD-----------------------------------DPDLQALLKGSQLLKVKSSS-------WRRERFYKLQEDCKTIWQESRKV--MRSPESQLFSIEDIQEVRMGHRTEGLEK---------FAR-DIPEDRCFSIVFKD---QRNTLDLIAPSPADAQHWVQGLRKIIHHSGSMD--------------QRQKLQHWIHSCLRKADK-------NKDNKMNFKELKDFLKELNIQVDDGYARKIFRECDHS---QTDSLEDEEIETFYKMLTQRAEIDRAFEE----------AAGSAE--TLSVERLVTFLQHQQREEEAGPALA--------LSLIERYEPSETAKAQRQMTKDGFLMYLLSADGNAFSLAHRRVYQD-MDQPLSHYLVSSSHNTYLLEDQLTGPSSTEAYIRALCKGCRCLELDCW--DGPNQEPIIYHGY---------------TFTSKILFCDVLRAIRDYAFKASPYPVILSLENHCS-LEQQRVMARHLRAILGPILLDQPL-DGVTT----SLPSPEQLKGKILLKGKKLGGLLPAGGENGSEATDVSDEVE-----------------------------------------------------------------------AAEMEDEA----------------VRSQVQHKPKEDKLK------------------------------------------LVPELSDMIIYCKSVHFGGFSSPGTSGQAF---------------------YEMASFSESRALRLLQESGN--GFVRHNVSCLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYLGCFQDNGG-------CGYVLKPA---FLRDPNTTFNSRALTQGPWWRPERLRVRIISGQQLPKVN---KNK-NSIVDPKVIVEIHG-------VGRDTGSRQTAVITN------NGFNPRWDME--FEFEVTVPDLALVRFMVED-YDSSSKNDFIGQSTIPWNSLKQG--YRHVHLLSKNGDQHPSATLFVKISIQD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51178-1", "uniprot_id": "PLCD1_HUMAN", "id": "P51178-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MDSGRDFLTLHGLQD-----------------------------------DEDLQALLKGSQLLKVKSSS-------WRRERFYKLQEDCKTIWQESRKV--MRTPESQLFSIEDIQEVRMGHRTEGLEK---------FAR-DVPEDRCFSIVFKD---QRNTLDLIAPSPADAQHWVLGLHKIIHHSGSMD--------------QRQKLQHWIHSCLRKADK-------NKDNKMSFKELQNFLKELNIQVDDSYARKIFRECDHS---QTDSLEDEEIEAFYKMLTQRVEIDRTFAE----------AAGSGE--TLSVDQLVTFLQHQQREEAAGPALA--------LSLIERYEPSETAKAQRQMTKDGFLMYLLSADGSAFSLAHRRVYQD-MGQPLSHYLVSSSHNTYLLEDQLAGPSSTEAYIRALCKGCRCLELDCW--DGPNQEPIIYHGY---------------TFTSKILFCDVLRAIRDYAFKASPYPVILSLENHCT-LEQQRVMARHLHAILGPMLLNRPL-DGVTN----SLPSPEQLKGKILLKGKKLGGLLPPGGEGGPEATVVSDEDE-----------------------------------------------------------------------AAEMEDEA----------------VRSRVQHKPKEDKLR------------------------------------------LAQELSDMVIYCKSVHFGGFSSPGTPGQAF---------------------YEMASFSENRALRLLQESGN--GFVRHNVGHLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYQGRFQDNGA-------CGYVLKPA---FLRDPNGTFNPRALAQGPWWARKRLNIRVISGQQLPKVN---KNK-NSIVDPKVTVEIHG-------VSRDVASRQTAVITN------NGFNPWWDTE--FAFEVVVPDLALIRFLVED-YDASSKNDFIGQSTIPLNSLKQG--YRHVHLMSKNGDQHPSATLFVKISLQD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BAJ8-1", "uniprot_id": "A0A8M2BAJ8_DANRE", "id": "A0A8M2BAJ8-1", "name": "Phosphoinositide phospholipase C", "aln": "-----------------------------------------------------------------------------------------------------------------MQCIRRQPTRTKSQESLYRAHIKTIARDNMKLLVLEG-----------------------------------DRDLQFLMNGGDLLKVRSES-------WKKTRYFKLQEDCKTMWHESKKT--LKT--KQTFSIEDIEEVRTGRQTDSLRK---------YTE-ETLEGRAFSILFKG---RQKSLDLIASTEEEAKKWVSGLEKVISSLNNLS--------------SQKKTEHWIYSSLRKADK-------NLDNKMSLKEVKSFLKDINVEVHEDYAEMLFKECDKS---NGGFLEGNEIEHFYKILTKREEIDVIYGE----------YAKTDG--LMSANDLLNFLLTEQREEVS-QNDA--------LQLIEKYELDENAKAKQQMTQDGFLMYLHQPEGLIFNQAHKSVYHD-MNQPLSHYFISSSHNTYLMEDQLKGPSSTEAYIRALLKGCRCVELDCW--DGSDGEPVIYHGY---------------TLTSKILFKDVIKAIKEYAFKTSEYPVILSLENHCG-VEQQKIMAQHLTSILGSALVTKPLGDQMPT----CLPAPEELKGRFIVKGKRLDKLENAFS----DESKMADEES-----------------------------------------------------------------------VSEEEDDE----------------GDEENNEK-KSGSLK------------------------------------------LAKELSDIVIYCKSVPFHGLED-SREKHSF---------------------YEMASFKEGKALKLAEESAT--EYIRHNTDKLSRIYPGGMRTDSSNYNPVPMWNAGCQIVALNFQTPCLEMDLNQGLFYQNGR-------SGYILKPS---YLRERDTEFDPITLTKGPWLKRKTLHVMVISAQQLPKVG---KRE-SAIVDPIVKVQVYG-------VPADTAAVETSYIKN------NGFNPMWNEN--FQLEVCVPDLALVRFLIED-YDSTSDNEFIGQYTLPFNSLRNG--YHHVPLLTQDGNLLSSAGLFVHIMVVDTE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8K2J0-1", "uniprot_id": "PLCD3_MOUSE", "id": "Q8K2J0-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3", "aln": "--------------------------------------------------------------------------------------------MLCGGWKRSRRSPEES----RVSAQVAAPLAFPPSPASSDSSTKRPGLRALKKMGLTE-----------------------------------DEDVQAMLRGSRLLKIRSRT-------WHKERLYRLQEDGLSVWFQRRIP---RAASKHIFFVQHIEAVREGHQSEGLRR---------FGG-AFAPACCLTIAFKG---RRKNLDLAAPTAEEAQRWVRGLAKLRARLDAMS--------------QRERLDHWIHSYLHRADS-------DQDSKMSFKEIKSLLRMVNVDMNDMYAYRLFKECDHS---NNERLEGAEIEAFLRRLLKRPELEEIFRR----------YSGEDR--VLSASELLEFLED-QGEDGATLACA--------QQLIQTYELNETAKQHELMTLDGFMMYLLSPEGAALNVAHTCVFQD-MGQPLAHYFISSSHNTYLTDSQIGGTSSTEAYIRAFAQGCRCVELDCW--EGPGGEPVIYHGH---------------TLTSKILFRDVIQAVRDHAFTSSPYPVILSLENHCG-LEQQAVMARHLRSILGDMLVTQALDSQNPE----ELPSPEQLKGRILVKGKKLP--AARSE----DGRILSDREE-----------------------------------------------------------------------EEEEEEEA----------------EEALEAAEQRSRAKQ------------------------------------------ISPELSALAVYCCATRLRTLDP-SPGPPQS---------------------CTVGSLSERKARKFTREAGT--SFVRHNTQQLTRVYPLGLRMNSANYNPQEMWNSGCQLVALNFQTPGYEMDLNTGRFLINGQ-------CGYVLKPA---YLRQLNTTFDPEC----PGPPRTTLAIQVLTAQQLPKLN---AEKPSSIVDPLVRVEIHG-------VPEDCAQKETDYVLN------NGFNPCWEQT--LQFRLRAPELVLVRFVVED-YDTTSPNDFVGQSTLPLSSLKQG--YRHIHLLSKDGASLAPATLFVHIRIQNS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LMR7-1", "uniprot_id": "A0ABK0LMR7_RAT", "id": "A0ABK0LMR7-1", "name": "Phosphoinositide phospholipase C", "aln": "--------------------------------------------------------------------------------------------MLCGGWRRSRRSPEEP----RVSAQVAAPLAFLPSPASSDSSTKRPGLRALKKMGLTE-----------------------------------DEDVQAMLRGSKLLKIRSRT-------WHKERLYRLQEDGLSVWFQRRIP---RAASQHIFFVQHIEAVREGHQSEGLRR---------FGG-AFAPARCLTIAFKG---RRKNLDLAAPTAEEAQRWVRGLAKLRARLDAMS--------------QRERLDHWIHSYLHRADS-------DQDSKMSFKEIKSLLRMVNVDMNDMYAYRLFKECDHS---NNERLEGAEIEAFLRRLLKRPELEEIFRR----------YSGEDR--VLSASELLEFLED-QGEDGATLACA--------QKLIQTYELNETAKQHELMTLDGFMMYLLSPEGAALNVAHTCVFQD-MGQPLAHYFISSSHNTYLTDSQIGGTSSTEAYIRAFTQGCRCVELDCW--EGPGGEPVIYHGH---------------TLTSKILFRDVIQAVRDHAFTLSPYPVILSLENHCG-LEQQIVMARHLRNILGDMLVTQALDSQNPE----ELPSPEQLKCRVLVKGKKLP--AARNE----DGRILSDRED-----------------------------------------------------------------------EDEDEEEA----------------EEALETAEQRKRAKQ------------------------------------------ISPELSALVVYCCATRLRTLEP-SPGPPQP---------------------CKIGSLSERKARKFTREAGT--SFVRHNTQQLTRVYPLGLRMTSANYNPQEMWNSGCQLVALNFQTPGYEMDLNTGRFLINGQ-------CGYVLKPA---YLRQLNTTFDPEC----PGPPRTTLTVQVLTAQQLPKLN---VEKPNSIVDPLVRVEIYG-------VPEDCAHKETDYVLN------NGFNPCWEQT--LQFQLRAPELVLVRFVVED-YDTTSPNDFVGQFTLPLNSLKQG--YRHIHLLSKDGASLSPATLFVHIRIENS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N3E9-1", "uniprot_id": "PLCD3_HUMAN", "id": "Q8N3E9-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3", "aln": "--------------------------------------------------------------------------------------------MLCGRWRRCRRPPEEPPVAAQVAAQVAAPVALPSPPTPSDGGTKRPGLRALKKMGLTE-----------------------------------DEDVRAMLRGSRLRKIRSRT-------WHKERLYRLQEDGLSVWFQRRIP---RAPSQHIFFVQHIEAVREGHQSEGLRR---------FGG-AFAPARCLTIAFKG---RRKNLDLAAPTAEEAQRWVRGLTKLRARLDAMS--------------QRERLDHWIHSYLHRADS-------NQDSKMSFKEIKSLLRMVNVDMNDMYAYLLFKECDHS---NNDRLEGAEIEEFLRRLLKRPELEEIFHQ----------YSGEDR--VLSAPELLEFLED-QGEEGATLARA--------QQLIQTYELNETAKQHELMTLDGFMMYLLSPEGAALDNTHTCVFQD-MNQPLAHYFISSSHNTYLTDSQIGGPSSTEAYVRAFAQGCRCVELDCW--EGPGGEPVIYHGH---------------TLTSKILFRDVVQAVRDHAFTLSPYPVILSLENHCG-LEQQAAMARHLCTILGDMLVTQALDSPNPE----ELPSPEQLKGRVLVKGKKLP--AARSE----DGRALSDREE-----------------------------------------------------------------------EEEDDEEE----------------EEEVEAAAQRRLAKQ------------------------------------------ISPELSALAVYCHATRLRTLHP-APNAPQP---------------------CQVSSLSERKAKKLIREAGN--SFVRHNARQLTRVYPLGLRMNSANYSPQEMWNSGCQLVALNFQTPGYEMDLNAGRFLVNGQ-------CGYVLKPA---CLRQPDSTFDPEY----PGPPRTTLSIQVLTAQQLPKLN---AEKPHSIVDPLVRIEIHG-------VPADCARQETDYVLN------NGFNPRWGQT--LQFQLRAPELALVRFVVED-YDATSPNDFVGQFTLPLSSLKQG--YRHIHLLSKDGASLSPATLFIQIRIQRS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5D6R3-1", "uniprot_id": "PLD3A_DANRE", "id": "A5D6R3-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A", "aln": "-----------------------------------------------------------------------------------------------------------------MLGRKKNPETVQTESKSVESKTHDP----LRRLGVLD-----------------------------------DEDVLLMLQGSKMMKVRSQR-------WRKDRRLKLLEDCVTVWCESSKTS-RKSNRQQTFSVTEVECVREGCQSECLRR---------MTD-LVPEKNCFTVVFRG---GRKSLDLCCHTQEEAERWVRGIRTLKDRVSNMS--------------QKEKLDHWIRGYLRRADQ-------NQDGKMSYDEVKHLLQLINIDLNEQYARTLFKKCDRS---CDGRLDHVEIEEFCREMMRRPELDAVFRH----------YSGNGC--VLTTLELRDFLGD-QGED-ASLVHA--------KSLIQTFELNDWAQKNLFMTQNGFTMYMLSKENDVFNPDHTHVYQD-MSKPLAHYYISSSHNTYLTKDQVTSASSTEPYIRALNQGCRCVELDCW--DGDKGEPIIYHGH---------------TLTSKVLFKEVIETIAQYAFKASPYPLILSLENHCS-VEQQAIMAQQLQSILGKKLLAKPLSDLPLK----QLPSPEELKGRILLKGKKLNGLLGKTE----SWTSFTNSSD-----------------------------------------------------------------------EESVAGGN----------------KKESKKDLARSASTK------------------------------------------LSPELSDLVVYCQSVPFSGFET-ANQRP-P---------------------SVITSFSENEALKLIKDSGK--LFVRNNSRQLSRIYPSAQRLQSSNFDPQDMWNAGCQMVALNFQTPGEQMDLNQGRFLPNGR-------CGYVLKPE---FLCDPKSDFDPENTGGGPGHIPTQLTIRVISAQQLPKIN---TDKPNSIVDPQVWVEIHG-------VSIDKARAKTQRIDN------NGFNPRWDCT--VSFQLQLPELALVRFMVED-HDHKSKNDFIGQFTLPFTSLRTG--YRHVHLLKADGSTLSPATLFIHVKVVRRGV--------------------HIKTVSERIGKA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2AP18-1", "uniprot_id": "PLCH2_MOUSE", "id": "A2AP18-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2", "aln": "---MGGLAWG---PSRAAGSSWVN---ASGTWEQPLRGFSG---LQ------GGRRRGRGEKGIPEEPLCQLTPQLGLSLRVPFGLGDYGLDMPGPQPS--------------AASQTTGAVACLAEVLLWVG--GSVVVSPRWQLSLVV-----------------------------------ERCMSAMQEGTQMVKLRGSS-------KGLVRFYYLDEHRSCLRWRPSRK-----NEKAKISIDSIQEVSEGRQSEIFQR---------YPDSSFDPNCCFSIYHGS---HRESLDLVSPSSEEARTWVTGLRYLMAGISDEDSLA----------RRQRTRDQWLKQTFDEADK-------NGDGSLSISEVLQLLHKLNVNLPRQRVKQMFREADTDD--HQGTLGFEEFCAFYKMMSTRRDLYLLMLT----------YSNHKD--HLDASDLQRFLEVEQKMNGVTLESC--------QNIIEQFEPCLENKSKGMLGIDGFTNYTRSPAGDIFNPEHNRVHQD-MTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVLQAGCRCVEVDCW--DGPDGEPIVHHGY---------------TLTSKILFKDVIETINKYAFIKNEYPVILSIENHCS-VVQQKKMAQYLTDILGDKLDLSSVSSEDAT----MLPSPQMLKGKILVKGKKLPANISEDAEEGEVSDEDSADEMEDDCKL-LNGDASTNRKRVENIAKKKLDSLIKESKIRDCEDPNDFSVSTLSPSGKLGRKAEAKKGQSKVEEDVEAGEDS----------GVSRQNSRLFMSSFSKRKKKG-----SKIKKVASVEEGDETLDSPGSQSRGTARQ---KKTMKLSRALSDLVKYTKSVGTH--DVEIE-VVSS---------------------WQVSSFSETKAHQILQQKPT--QYLRFNQHQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGD-------CGYVLKPQ---CMCQG--VFNPNSEDPLPGQLKKQLALRIISGQQLPKPRDSVLGDRGEIIDPFVEVEVIG-------LPVDCSKEQTRVVDD------NGFNPMWEET--LVFTVHMPEIALVRFLVWD-HDPIGR-DFIGQRTLAFSSIMPG--YRHVYLEG-----MEEASIFVHVAVSDISG--------------------KVKQTLGLKGLFLRGTKPGSLDSHAAGQPLPRPSVSQRLLRRTASAPT--------------------KSQKPSRKGFPELALGTQDAGSEGAADD--------------------------VAPSSPNPALEAPTQERSGSSSPRDTRLFP-LQRPISPLCS--LEPIAEEPAL-GPGLPLQAAAPTG-----PSQEGSQCPVGLGAKVTSSQQTSLGAFGTLQLRIGGGRENEEPPL---------------------RPHNGGISSGPREGTSGRQTDSKS-------------------------RSRVPGHLPVVRRAKSEGQVLSELS----------PTPAVYSDATGTDR----LWQRLEPGSHRDSVSSSSSMSSND---------------TVIDLSLPSLG----LCRSRESIPGVSLGRLTSRPCLASAARPDLPPVTKSKSNPNLRVAGGLPTAPDELQPRPLAPR--------------------------------------------------------------------------------------------------------------------------LTGHHPRPPWHHLTLVGLRDCP-------------------------------VSAKSKSLGDLTADDFAPSFQGSTSSLSCGLGSLGVAHQ-----VLEPGIRRDALTEQLRWLTGFQQAG--DITSPTSLGPAGDGSVGGPSFLRRSSSRSQSRVRAIASRARQAQERQQRLRGQ----------------------------------DSRGPPEEERGTPEGACSVGHEGCVDVPMPAK---GAPEQVCGAADGQLLLRL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GLE1-1", "uniprot_id": "A0A8I6GLE1_RAT", "id": "A0A8I6GLE1-1", "name": "Phosphoinositide phospholipase C", "aln": "MTSLSALLWLRGAASRCGKRSQPRPLLVQGSGHAEARGEAAGASLQKEYFGCGGARGGCWPRCPPGSQSLRVALARGSTSRPALRAALPGPPAPSQRGAGRGCGAGGTSDSALLARRLHGAQCHSAERAARTVRRGSPALAKRCPRSLSLSQSQATDHPSPRPRGHLAAVNAETMDAGAAPQKHMERCMSAMQEGTQMVKLRGSS-------KGLVRFYYLDEHRSCLRWRPSRK-----NEKAKISIDSIQEVSEGRQSEIFQR---------YPDSSFDPNCCFSIYYGS---HRESLDLVSPSSEEARTWVTGLRYLMAGISDEDSLA----------RRQRTRDQWLKQTFDEADK-------NGDGSLSISEVLQLLHKLNVNLPRQRVKQMFREADTDD--HQGTLGFEEFCAFYKMMSTRRDLYLLMLT----------YSNHKD--HLDASDLQRFLEVEQKMSGVTLESC--------QSIIEQFEPCLENKSKGVLGIDGFTNYTRSPAGDIFNPEHHRVHQD-MTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVLQAGCRCVEVDCW--DGPDGEPIVHHGY---------------TLTSKILFKDVIETINKYAFIKNEYPVILSIENHCS-VVQQKKMAQYLTDILGDKLDLSSVSGEDAT----MLPSPQMLKGKILVKGKKLPANISEDAEEGEVSDEDSADEIEDDCKL-LNGDASTNRKRVENIAKKKLDSLIKESKIRDCEDPNDFTVSTLSPSGKLGHKAEAKKAQSKAEEDVESGEDT----------GVSRRNSRLLMSSFSKRKKKG-----SKIKKVASVEEGDESLDSPGSQSRGTARQ---KKTMKLSRALSDLVKYTKSVGTH--DVEME-VVSS---------------------WQVSSFSETKAHQILQQKPA--QYLRFNQHQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGG-------CGYVLKPQ---CMCQG--VFNPNSEDPLPGQLKKQLALRIISGQQLPKPRDSVLGDRGEIIDPFVEVEVIG-------LPVDCSKEQTRVVDD------NGFNPMWEET--LVFTVHMPEIALVRFLVWD-HDPIGR-DFIGQRTLAFSSMMPG--YRHVYLEG-----MEEASIFVHVAVSDISG--------------------KVKQTLGLKGLFLRGPKPGSLDSHAAGQPLPRPSVSQRLLRRTASAPT--------------------KSQKPSRKGFPELALGTQDAGSEGAADD--------------------------VAPPSPNPALEAPTQERSGSSSPRDTRLFP-LQRPISPLCS--LEPIAEEPAL-GPGLPLQAAVPTG-----PSQEGPQCPVGQGAKVTGPQQTSLGASGTLQLRTGGDREKEEPPL---------------------RPHNGGIPHGPREGTSGRQTDSKS-------------------------RSWAPGHLPVVRRAKSEGQVLSELS----------PTPAVYSDATGSDR----LWQRLEPGSHRDSVSSSSSMSSND---------------TVIDLSLPSLG----LCRSRESIPGVSLGRLTPRPCLASAARPDLPPVTKSKSNPNLRVAGGLPLAPDELQPRPLAPR--------------------------------------------------------------------------------------------------------------------------LTGLHSRPPWHHLTLVGLRDCP-------------------------------VSAKSKSLGDLTADDFGPSFQGSTGSLSCGLSPLGVVHQ-----VLEPGRRRDALTEQLRWLTGFQHAG--DITSPTSLGPAADGSVGGPSFLRRSSSRSQSRVRAIASRARQAQERQQRLRGL----------------------------------DSRGPPEEERGTPEGACSVGHEGCVDVPMPAK---GAPEQVCGAADDQLLLRL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75038-1", "uniprot_id": "PLCH2_HUMAN", "id": "O75038-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2", "aln": "--------------------------------------------------------------------------------------------MSGPWPS--------------PDSRTKGTVAWLAEVLLWVG--GSVVLSSEWQLGPLV-----------------------------------ERCMGAMQEGMQMVKLRGGS-------KGLVRFYYLDEHRSCIRWRPSRK-----NEKAKISIDSIQEVSEGRQSEVFQR---------YPDGSFDPNCCFSIYHGS---HRESLDLVSTSSEVARTWVTGLRYLMAGISDEDSLA----------RRQRTRDQWLKQTFDEADK-------NGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDD--HQGTLGFEEFCAFYKMMSTRRDLYLLMLT----------YSNHKD--HLDAASLQRFLQVEQKMAGVTLESC--------QDIIEQFEPCPENKSKGLLGIDGFTNYTRSPAGDIFNPEHHHVHQD-MTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVLQAGCRCVEVDCW--DGPDGEPIVHHGY---------------TLTSKILFKDVIETINKYAFIKNEYPVILSIENHCS-VIQQKKMAQYLTDILGDKLDLSSVSSEDAT----TLPSPQMLKGKILVKGKKLPANISEDAEEGEVSDEDSADEIDDDCKL-LNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVSTLSPSGKLGRK-------SKAEEDVESGEDA----------GASRRNGRLVVGSFSRRKKKG-----SKLKKAASVEEGDEGQDSPGGQSRGATRQ---KKTMKLSRALSDLVKYTKSVATH--DIEME-AASS---------------------WQVSSFSETKAHQILQQKPA--QYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGG-------CGYVLKPG---CMCQG--VFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGEIIDPFVEVEIIG-------LPVDCSREQTRVVDD------NGFNPTWEET--LVFMVHMPEIALVRFLVWD-HDPIGR-DFIGQRTLAFSSMMPG--YRHVYLEG-----MEEASIFVHVAVSDISG--------------------KVKQALGLKGLFLRGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPT--------------------KSQKPGRRGFPELVLGTRDTGSKGVADD--------------------------VVPPGPGPAPEAPAQEGPGSGSPRDTRPLS-TQRPLPPLCS--LETIAEEPAP-GPGPPPPAAVPTS-----SSQGRPPYPTGPGANVASPLEDTE--------------EPRDSRP---------------------RPCNGEGAGGAYERAPGSQTDGRS-------------------------QPRTLGHLPVIRRVKSEGQVPTEPLGGWRPLAAPFPAPAVYSDATGSDP----LWQRLEPCGHRDSVSSSSSMSSSD---------------TVIDLSLPSLG----LGRSRENLAGAHMGRLPPRPHSASAARPDLPPVTKSKSNPNLRATGQRPPIPDELQPRSLAPR--------------------------------------------------------------------------------------------------------------------------MAGLPFRPPWGCLSLVGVQDCP-------------------------------VAAKSKSLGDLTADDFAPSFEGGSRRLSHSLGLPGGTRR-----VSGPGVRRDTLTEQLRWLTVFQQAG--DITSPTSLGPAGEGVAGGPGFVRRSSSRSHSRVRAIASRARQAQERQQRLQGL----------------------------------GRQGPPEEERGTPEGACSVGHEGSVDAPAPSK---GALGPASAAAENLVLLRL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PAP8-1", "uniprot_id": "A0A8M1PAP8_DANRE", "id": "A0A8M1PAP8-1", "name": "Phosphoinositide phospholipase C", "aln": "------------------------------------------------------------------------------MDTASLNTSLFSGSMSTDSPN--------------LSTRSMGFTTDTDSSRSSTLLHCNHFLAANYIS--VV-----------------------------------EKCMSSMQTGTQMVKLRGGS-------KGLVRFFYLDEHKSCIRWRPSRK-----NEKAKISIDSIREVCEGKQSEIFQR---------YSDGSFDPNCCFSIYYGE---HMESLDLVSGTGEEARTWITGLKYLMAGISDEDSLA----------KRQRTRDQWLKQTFAEADK-------NGDGCLSISEVLQLLHKLNVNLPRQKVKQMFKEADTDD--NQGTLGFEEFCSFYKMMSTRRDLYLLMLT----------YSNHKD--HLDTDDLKRFLETEQKMTNVSKEHC--------LEIVAKFEPCPENQTSGVLGIDGFTNYMRSPAGDIFNPEHYEVNQD-MTQPLSDYFIASSHNTYLMGDQLMSQSRVDMYAWVLQAGCRCVEVDCW--DGQDGEPIVHHGY---------------TLTSKILFKDVIETINKYAFAKNQYPVILSIENHCS-VPQQKKMAQYLTEVLGDKLDVSSIPADPSG----LLPSPEALKGKILIKGKKLPSNIDENAEEGDVSDEDSADEMEDDCKL-LNGDTSMNRKQAENVAKKKLDNLMKESKIRDREDPDSFTITALPPSGKHDKSP----LKGKAEDSTDTGDEAN--------IGGNKRLARTFMGSFSKRKKKT-----SKVKKSSSFEDTDTDQESSSGASKAQAHHSRKKKTMKLSRALSDLV-YMKSVGMP--DFESQ-GVT----------------------WQVSSMSETKAHQLIQQKPV--PFMRFNQRQLSRVYPSPYRVDSSNFNPQPFWNAGCHLVALNYQSEGRVLQLNRAKFYCNGN-------CGYIQKPG---CLCEG--SFNPVAEDPLPGRLKKQLILKVISGQQLPKPKDSMLGDRGEIIDPFVEVEIIG-------LPVDCCKEQTRVVDD------NGFNPMWEET--LVFTLHMPENALIRFLVWD-HDPIGQ-DFIGQRTIAFNSMIPG--YRHVYLEG-----MEEASIFVHVAVNDITS--------------------KARAVSGIKGLFHRNPKQASLDSHAAALLNRKSTFGAHLLRRTASAPT--------------------KGQPKVKRGFPEISIDTKDCSSDGASEERESEEGP------------------LVHHNGDTASAKSWGQGTNGQLHPDDRKENSEVQSPTPSLNASCLESITENFQENSPSTSTQSPVDTSPHCPLSSPSTAITASSNGENLSPVKNNEDILKSFALTQSTSGKDSGNSPVNSSISTNYLDIGCDTPTFPTFHRADGEVAQETVINQTGLTLEIDAGKEPTAIQSSQRIQALKAVFDRDIGRSMQTGLRTPVRRSKSEGQMKKADG--------PSVVPEVCTDATLNDR----LWSKLDPSSHRDSVSSSSSISSND---------------TVIDLSLPNLSRKSLTCLSAARDYSDKQASLTNN-HRSVIAGCGVSLVSKSKSNPNLR-DGEMCNTDDDLQPRPLVADK-----------------------------------------------------------------------------------------------------------------------DPIRPMQRRHTWSRLYVEGLKQSSTL-------------AASAASKKSTTLSAKDIDSKSKSLGDLTSDDIICNFESKYRSISRSFIVRPSRQH-----GKTLRKPQNDFTEQLKRLTDVEPLTSKDFAQCRADSEAGQEEEEMP-PLRRSSSRSQSRVRYIANRARQAQERQRLQSIT----------------------------------RMSGSPIEERGNPEGACSVPHSPCTCLDLLSQLPPGPPQQSPLSPDNEVFFMLRL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PVI9-1", "uniprot_id": "A0A8M9PVI9_DANRE", "id": "A0A8M9PVI9-1", "name": "Phosphoinositide phospholipase C", "aln": "-----------------------------------------------------------MNSSPAMAPSSPVLFSPSLARRPPSPGRRPNTNFRSASPS----------IMTSPKLWQKAAISRLAEEFFWIG--GSIVASPKWRMGQIV-----------------------------------ERCMCNMQAGSQMIKLRGKS-------KALVRLFYLDEHKSCIRWRPSRK-----HERAKITIDSIHEVCEGMRTEVFRR---------FANNNFDPNCCFSIYHGD---HVESLDLVSTNGEEARTWITGLKYLLAGISDEDSLA----------KRQRTRDQWLRQTFSEADK-------NGDGNLSIGEVLQLLHKLNVNLPKQKVREMFQEADTDE--NQGSLTFEEFCTFYKLISTRRDLYLLMIS----------YSNHKE--HLDLNDLQRFLESEQKMVNVTKEYC--------KMIINQFEPCSQNQSHVVLGIDGFTNYMRSPAGDIFNPEHYQVNQD-MTQPLTNYYIASSHNTYLTGDQLLSQSRVDMYAYVLQMGCRCVEVDCW--DGPDGEPIVHHGY---------------TLTSKILFKDVVETINKYAFAKTQFPVILSIENHCT-VPQQKKMAQYLMEVLQDKVDLSNINTNESR----RLPSPEDLKGKILVKGKKLPANIDADADEGDVSDEDSGEEDEEEELQ-LNGDTTEG-----------------------------------------------------APESASADESK-------------KRSRRKFMGSFRRKKKKQ-----VKVKKKPIVSDSDTEPEITSTNDKQVINYGKRRKTMRLSRALSDLVKYTKSVRVH--DIETQAYMSS---------------------WQVSSLNESITNQILQLKPA--QLVRFNQRQLLRVYPSNYRVDSSNFNPQPFWNAGCHLVALNYQTEGRMLQLNRAKFAANGN-------CGYVLKPK---CMCKG--AFNPVLEDPLPGHRKSQLVLKIISGQQLPKPKDSMLGDRGEIIDPFVEVEIIG-------LPIDCNKQQTRVVDD------NGFNPTWEET--LVFTLHMPQIALVRFMVWD-HDPIGR-DFIGQRTISFKSMMPG--YRHVYLEG-----MEEASIFVHVAVNDITG--------------------KVKSSNAVKQLIQKNLMQTSED-------GTRKSFAPNFLRKSGKNQS--------------------KVVK-------VECYTKEDFLNRRYSDD--------------------------VSSKDSRSTSQSASLLRGAQSEPLKRAHRVSFQEPEG----------SHEPRRRLSSIP-----YTG--------------------------------------------------------------------------------GAAVDYTNLAFDSHS---------------------------------------SSELDIQTFSH------------LEDNTESKQNDS----LSSKLEFESTDIPKSPASTLNEQC---------------LSRQISAANEH-------SEQKPEMSKMIHSVPDPLNFHPIPDGVLDPSRGTLNTLVPQNKFRSSLDARLNPR----------------------------------------------------------------------------------------------------------------------------------------WQPLSIPATPALN---------------------------------------RRMNDKGTPNSLLKGCRSQSVPRRRPTSPPN-----TPG-HIRRDPINQYFLPQCSYTTAN--DLVPNNHNIAESES----------SSLSSLDSLDLSTLPCRFPDNQQQTMGTL----------------------------------QREMNALFEQKIQEIRCHS--------PLFFR-------------DSSTL-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q4KWH5-1", "uniprot_id": "PLCH1_MOUSE", "id": "Q4KWH5-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1", "aln": "-------------------------------------------------------------------------------------------------------------------MADLEVYKNLSPEK-------------------------------------------------------VERCMSVMQSGTQMIKLKRGT-------KGLVRLFYLDEHRTRLRWRPSRK-----SEKAKILIDSIYKVTEGRQSEIFHR---------QAEGNFDPSCCFTIYHGN---HMESLDLITSNPEEARTWITGLKYLMAGISDEDSLA----------KRQRTHDQWVKQTFEEADK-------NGDGLLNIEEIHQLMHKLNVNLPRRKVRQMFQEADTDE--NQGTLTFEEFCVFYKMMSLRRDLYLLLLS----------YSDKKD--HLTVEELAQFLKVEQKMSNVTLDYC--------LDIIMKFEVSEENKVKNVLGIEGFTNFMRSPACDVFNPLHHEVYQD-MDQPLCNYYIASSHNTYLTGDQLLSQSKVDMYARVLQEGCRCVEVDCW--DGPDGEPVVHHGY---------------TLTSKILFRDVVETINKHAFVKNEFPVILSIENHCS-IQQQRKIAQYLKGILQDKLDLSSVDTGECR----QLPSPQSLKGKILVKGKKLPYHLGDDAEEGEVSDEDSADEIEDECKFKLHYSNGTTEHQVESFIRKKLESLLKESQIRDKEDPDSFTVRALLKATHEGLN-------AHLKQNLDVKESG------------KKSHGRSLMANFGKHKQKAT----KSRSKSYSTDDEDDSLQNPGKEGGQLYRLGRRRRTMKLCRELSDLVVYTNSVAAQ--DIVDD--GTT---------------------GNVLSFSETRAHQVVQQKSE--QFMIYNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNYQSEGRMMQINRAKFKANGN-------CGYILKPQ---QMCKG--TFNPFSGDPLPANPKKQLILKVISGQQLPKPPDSMFGDRGEIIDPFVEVEIIG-------LPVDCCKDQTRVVDD------NGFNPVWEET--LTFTVHMPEIALVRFLVWD-HDPIGR-DFVGQRTVTFSSLVPG--YRHVYLEG-----LTEASIFVHITINEIFGKWSPLILNPSYTILHFLGATKNRQLQGLKGLFNKNPRHASSENNS--HYVRKRSIGDRILRRTASAPA--------------------KGRKKSKVGFQEMVEIKDSVSEASRDQDGVLRRTTRSLQVRPVSMPVDKSLLGALSLPISEAAKDTDGKENCLAGDKDDRRKGAATRKDPHFSNFNKKLSSSSSALLHKDA-NQGPTASVSNP----EQCGGRGAKSERIKPNMTNDCQENHNPPKFLSPRKHLALDPATKGLQERLHGMKTNEKE--HAEGFLGEKSMLSGSVLSQSSLEVENLEG-------------------SRAKGRAATSFSLSDVSALCSDIPDLHSTAILQDTEISNLIDDVTLTNENQSGSSISALIGQFEESNHPANVTVVS-HLSTSGASG------SAPFQTPFKHGLSQGNQKASFLCSSPELNKLSSVETTKLANNAVPCGVIGSPISTPKPGDDPSDKAKTRVIEGNLPGFPDASPGQFPKSPTHGEDHSQVMN-SPALSTELAIEDIIADPALSINSAESSLVEIDGESENLSLTTCDYREEAPSQLVSPLKLQQSQEMVEHIQRGLRNGYCKETLLP--SEIFNNIPGVKNHSISHLTYQGAGFVYNHFSSSDAKTNQICEPQQPRAPDMHAPTPTPSTHAPLAALKLPSPCKSKSLGDLTSEDIACNFESKYQCISRSFVTNGIRDK-SVTMKTKSLEPLDALTEQLRKLVSFDQED-----SCQVLYSKQDVNQCPRALVRKLSSRSQSRVRNIASRAKEKQEAGKQKAMAQSTRGGVVLRSKPPAPALAVNRHSTGSYIASYLRNMKAGGLEGRGIPEGACTALRYGYMDQFCSDNSVLQTEPSSEDKPEIYFLLRL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A096MJ91-1", "uniprot_id": "A0A096MJ91_RAT", "id": "A0A096MJ91-1", "name": "Phosphoinositide phospholipase C", "aln": "-------------------------------------------------------------------------------------------------------------------MADLEVYKNLSPEK-------------------------------------------------------VERCMSVMQSGTQMIKLKRGT-------KGLVRLFYLDEHRTRLRWRPSRK-----SEKAKILIDSIYKVTEGRQSEIFHR---------QAEGNFDPSCCFTIYHGN---HMESLDLITSNPEEARTWITGLKYLMAGISDEDSLA----------KRQRTHDQWVKQTFEEADK-------NGDGLLNIEEIHQLMHKLNVNLPRRKVRQMFQEADTDE--NQGTLTFEEFCVFYKMMSLRRDLYLLLLS----------YSDKKD--HLTVEELAQFLKVEQKMSNVTLDYC--------LDVIKKFEVSEENKVKNVLGIEGFTNFMRSPACDVFNPLHHEVYQD-MDQPLCNYYIASSHNTYLTGDQLLSQSKVDMYARVLQEGCRCVEVDCW--DGPDGEPVVHHGY---------------TLTSKILFKDVVETINKHAFVKNEFPVILSIENHCS-IQQQRKIAQYLKGIFQDKLDLSSVDTGECR----QLPSPQSLKGKILVKGKKLPYHLGDDAEEGEVSDEDSADEIEDECKFKLHYSNGTTEHQVESFIRKKLDSLLKESQIRDKEDPDSFTVRALLKATHEGLN-------AHLKQNLDVKESG------------KKSHGRSLMANFGKHKKTP-----KSRSKSYSTDDEEDTLQNPGKEGGQLYRLGRRRRTMKLCRELSDLVVYTNSVAAQ--DIVDD--GTT---------------------GNVLSFSETRAHQVVQQKSE--QFMIYNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNYQSEGRMMQINRAKFKANGN-------CGYILKPQ---QMCKG--TFNPLSGDPLPANPKKQLILKVISGQQLPKPPDSMFGDRGEIIDPFVEVEIIG-------LPVDCCKDQTRVVDD------NGFNPVWEET--LTFTVHMPEIALVRFLVWD-HDPIGR-DFVGQRTVTFSSLVPG--YRHVYLEG-----LTEASIFVHITINEIFG--------------------KNRQLQGLKGLFNKNPRHGSSENNS--HYVRKRSIGDRILRRTASAPA--------------------KGRKKSKVGFQEMVEIKDSVCEATRDQDGVLRRTTRSLQLRPVSMPVDKNLLGALSLPISEAAKNTDGKENYLAEDKDDGRKGPATIKDPHFSNFNKKLSSSSSALLHKDAKNQGPTASVSNP----EQCGGLGLKSGRIKPHMTNDCQENRSPQNFLSPRKHLALDPATKGLQD-LHGMRTDEKEQERAKGFVGRKSTQSESVLSQSSLEVENLEG-------------------SKAKGRAATSFSLSDVSALCSDIPDLHSTAILQDTEISDLINDVTLTNANESGSSISALIGQFEESNHRANVAVVSRLLSTSGTSEGVALPVALGLQTPIKNGFSQGKHKASFLCSSPELNKPSSAETTKLANNTVACGVIGSPISTPKPGDDASDKAKTRVTEDNLPDSPDAFPGQFPQSPTHGEDHRQVMS-SPALSMPLAMEDTTADPALCINSEESSLVEIDGDSESLSLTACDYGEEALSQLVSPLKLQQSQETVEHIQKGLSNGYCKETLLP--SEIFNNIPGVKNQSISHLTYQGAGFVYNHFSSSDAKTNQICGPQQPRAPDMHVPTPTPSTHAPLAALKLPSPCKSKSLGDLTSEDIACNFESKYQCISRSFVTNSIRDK-SVTMKTKSFEPLDALTEQLRKLVSFDQED-----SCQGLYSKQDVNQCPRALVRKLSSRSQSRVRNIASRAKEKQEAGKQKAMTQNPRGGVVLRSKPPAPTLAVNRHSTGSYIASYLRNMKASGLEGRGIPEGACTALRYGYMDQFCSDNSVLQTEPSSEDKPEIYFLLRL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4KWH8-1", "uniprot_id": "PLCH1_HUMAN", "id": "Q4KWH8-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1", "aln": "-------------------------------------------------------------------------------------------------------------------MADLEVYKNLSPEK-------------------------------------------------------VERCMSVMQSGTQMIKLKRGT-------KGLVRLFYLDEHRTRLRWRPSRK-----SEKAKILIDSIYKVTEGRQSEIFHR---------QAEGNFDPSCCFTIYHGN---HMESLDLITSNPEEARTWITGLKYLMAGISDEDSLA----------KRQRTHDQWVKQTFEEADK-------NGDGLLNIEEIHQLMHKLNVNLPRRKVRQMFQEADTDE--NQGTLTFEEFCVFYKMMSLRRDLYLLLLS----------YSDKKD--HLTVEELAQFLKVEQKMNNVTTDYC--------LDIIKKFEVSEENKVKNVLGIEGFTNFMRSPACDIFNPLHHEVYQD-MDQPLCNYYIASSHNTYLTGDQLLSQSKVDMYARVLQEGCRCVEVDCW--DGPDGEPVVHHGY---------------TLTSKILFRDVVETINKHAFVKNEFPVILSIENHCS-IQQQRKIAQYLKGIFGDKLDLSSVDTGECK----QLPSPQSLKGKILVKGKKLPYHLGDDAEEGEVSDEDSADEIEDECKFKLHYSNGTTEHQVESFIRKKLESLLKESQIRDKEDPDSFTVRALLKATHEGLN-------AHLKQSPDVKESG------------KKSHGRSLMTNFGKHKKTT-----KSRSKSYSTDDEEDTQQSTGKEGGQLYRLGRRRKTMKLCRELSDLVVYTNSVAAQ--DIVDD--GTT---------------------GNVLSFSETRAHQVVQQKSE--QFMIYNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNYQSEGRMMQLNRAKFKANGN-------CGYVLKPQ---QMCKG--TFNPFSGDPLPANPKKQLILKVISGQQLPKPPDSMFGDRGEIIDPFVEVEIIG-------LPVDCCKDQTRVVDD------NGFNPVWEET--LTFTVHMPEIALVRFLVWD-HDPIGR-DFVGQRTVTFSSLVPG--YRHVYLEG-----LTEASIFVHITINEIYGKWSPLILNPSYTILHFLGATKNRQLQGLKGLFNKNPRHSSSENNS--HYVRKRSIGDRILRRTASAPA--------------------KGRKKSKMGFQEMVEIKDSVSEATRDQDGVLRRTTRSLQARPVSMPVDRNLLGALSLPVSETAKDIEGKENSLAEDKDGRRKGKASIKDPHFLNFNKKLSSSSSALLHKDTSQGDTIVSTAHMSVTGEQLGMSSPRGGRTTSNATSNCQENPCPSKSLSPKQHLAPDPVVNPTQD-LHGVKIKEKG--NPEDFVEGKSILSGSVLSHSNLEIKNLEG-------------------NRGKGRAATSFSLSDVSMLCSDIPDLHSTAILQESVISHLIDNVTLTNENEPGSSISALIGQFDETNNQA-LTVVSHLHNTSVMSGHCPLP-SLGLKMPIKHGFCKGKSKSSFLCSSPELIALSSSETTKHATNTV-YETTCTPISKTKPDDDLSSKAKTAALESNLPGSPNTSRGWLPKSPTKGEDWETLKSCSPASSPDLTLEDVIADPTLCFNSGESSLVEIDGESENLSLTTCEYRREGTSQLASPLKLKYNQGVVEHFQRGLRNGYCKETLRPSVPEIFNNIQDVKTQSISYLAYQGAGFVHNHFSDSDAKMFQTCVPQQSSAQDMHVPVPKQLAHLPLPALKLPSPCKSKSLGDLTSEDIACNFESKYQCISKSFVTTGIRDKKGVTVKTKSLEPIDALTEQLRKLVSFDQED-----NCQVLYSKQDANQLPRALVRKLSSRSQSRVRNIASRAKEKQEANKQKVPNPSNGAGVVLRNKPSAPTPAVNRHSTGSYIAGYLKNTKGGGLEGRGIPEGACTALHYGHVDQFCSDNSVLQTEPSSDDKPEIYFLLRL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3USB7-1", "uniprot_id": "PLCL1_MOUSE", "id": "Q3USB7-1", "name": "Inactive phospholipase C-like protein 1", "aln": "------------MAEGAAS-REAPAPLDVAGGEDDPRAGADAASGDAPPPALGGRMRDRRS--------------GVALPGAAGVPADSEAGLLEAARAT---------------PRRSSIIKDPSNQKCGG-RKKTVSFSSMPSEKKISS---------------------------------AHDCISFMQAGCELKKVRPNS-------RIYNRFFTLDTDLQALRWEPSKK----DLEKAKLDISAIKEIRLGKNTETFRNN--------GLADQICEDCAFSILHGE---NYESLDLVANSADVANIWVSGLRYLVSRSKQPLDFIEGNQ--------NTPRFMWLKTVFEAADV-------DGNGIMLEDTSVELIKQLNPTLKESKIRLKFKEIQKSKEKLTTRVTEEEFCEAFCELCTRPEVYFLLVQ----------ISKNKE--YLDANDLMLFLEAEQGVTHITEDMC--------LDIIRRYELSEDGRQKGFLAIDGFTQYLLSPECDIFDPEQKKVAQD-MTQPLSHYYINASHNTYLIEDQFRGPADINGYVRALKMGCRSIELDVS--DGPDNEPILCNRN---------------NMAMHLSFRSVLEVINKFAFVASEYPLILCLGNHCS-LPQQKVMAQQMKKVFGEKLYTEAPLSS-----ESYLPSPEKLKNMIIVKGKKLPSESDLLEGEVTDEDE-----------------------------------------------------------------------------EAEMS-------------------RRMSGDYNGEQ------------------------------------------KHIWLCRELSDLVSICKS--VQHRDFELSMKTQN--------------------YWEMCSFSETEASRIANEYPE--DFVNYNKKFLSRVYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDLHTGWFLQNGG-------CGYVLRPS---IMRDEVSYFSANTKGIVPGVSPLVLHIKIISGQNFPKPKG--ACAKGDVIDPYVCVEIHG-------IPADCCEQRTKTVQQ------NSDNPIFDET--FEFQVNLPELTMVRFVILD-DDYIGD-EFIGQYTIPFECLQPG--YRHVPLRSFVGDIMEHVTLFVHIAITNRSG------------------GGKPQKRSLSVRMGKKV-REYTMLRNIGLKTIDDIFKIAVHPLREAIDMR--------------------ENMQNAIVSVKELCG----------------------------------------LPPIASLKQCLLTLSSRLITSDSTPSVSLVMKDCFPYLEPLGAIPDVQKRMLAAYDLMIQESR----------------------------------------------------------------------------------------------------------------------------------------------------------VLIEMADTVQEKIVQCQKAGMEFHEELHNLGAKEGLKGRKLNKAIES--------------FAWNITVLKGQGDLLKNAKNEAVENIKQIQLACLSCGLSK-GPGGGSEAKGKRSLEAIEEKESSEENGKL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62688-1", "uniprot_id": "PLCL1_RAT", "id": "Q62688-1", "name": "Inactive phospholipase C-like protein 1", "aln": "------------MAEGAAS-REAPAPLDVAGGEDDPRAGADAASGDAAPEASGGRMRDRRS--------------GVALPGNAGVPADSEAGLLEAARAT---------------PRRTSIIKDPSNQKCGG-RKKTVSFSSMPSEKKISS---------------------------------AHDCISFMQAGCELKKVRPNS-------RIYNRFFTLDTDLQALRWEPSKK----DLEKAKLDISAIKEIRLGKNTETFRNN--------GLADQICEDCAFSILHGE---NYESLDLVANSADVANIWVSGLRYLVSRSKQPLDFMEGNQ--------NTPRFMWLKTVFEAADV-------DGNGIMLEDTSVELIKQLNPTLKESKIRLKFKEIQKSKEKLTTRVTEEEFCEAFCELCTRPEVYFLLVQ----------ISKNKE--YLDANDLMLFLEVEQGVTHVTEDMC--------LDIIRRYELSEDGRQKGFLAIDGFTQYLLSPECDIFDPEQKKVAQD-MTQPLSHYYINASHNTYLIEDQFRGPADINGYVRALKMGCRSIELDVS--DGPDNEPILCNRN---------------NMAMLLSFRSVLEVINKFAFVASEYPLILCLGNHCS-LPQQRVMVQQMKKVFGNKLYTEAPLSS-----ESYLPSPEKLKHMIIVKGKKLPSESDLLEGEVTDEDE-----------------------------------------------------------------------------EAEMS-------------------RRVSGDYNGEQ------------------------------------------KHIWLCRELSDLVSICKS--VQYRDFELSMKTQN--------------------YWEICSFSETLASRIANEYPE--DFVNYNKKFLSRVYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDLHTGWFLQNGG-------CGYVLRPS---IMRDEVSYFSANTKGIVPGVSPLLLHIKIISGQNFPKPKG--ACAKGDVIDPYVCVEIHG-------IPADCSEQRTKTVQQ------NSDNPIFDET--FEFQVNLPELTMVRFVILD-DDYIGD-EFIGQYTIPFECLQPG--YRHVPLRSFVGDIMEHVTLFVHIAITNRSG------------------GGKAQKRSLSVRMGKKV-REYTMLRNIGLKTIDDIFKIAVHPLREAIDMR--------------------ENMQNAIVSVKELCG----------------------------------------LPPIASLKQCLLTLSSRLITSDSTPSVSLVMKDCFPYLEPLGTIPDVQKRMLAAYDLMIQESR----------------------------------------------------------------------------------------------------------------------------------------------------------VLIEMADTVQEKIVQCQKAGMEFHEELHNLGAKEGLKGRKLNKAIES--------------FAWNITVLKGQGDLLKNAKNEAVENIKQIQLACLSCGLSK-GPGSAAEAKGKRSLEAIEEKESSEENGKL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15111-1", "uniprot_id": "PLCL1_HUMAN", "id": "Q15111-1", "name": "Inactive phospholipase C-like protein 1", "aln": "------------MAEGAAG-REDPAPPDAAGGEDDPRVGPDAAG-DCVTAASGGRMRDRRS--------------GVALPGAAGTPADSEAGLLEAARAT---------------PRRSSIIKDPSNQKCGG-RKKTVSFSSMPSEKKISS---------------------------------ANDCISFMQAGCELKKVRPNS-------RIYNRFFTLDTDLQALRWEPSKK----DLEKAKLDISAIKEIRLGKNTETFRNN--------GLADQICEDCAFSILHGE---NYESLDLVANSADVANIWVSGLRYLVSRSKQPLDFMEGNQ--------NTPRFMWLKTVFEAADV-------DGNGIMLEDTSVELIKQLNPTLKEAKIRLKFKEIQKSKEKLTTRVTEEEFCEAFCELCTRPEVYFLLVQ----------ISKNKE--YLDANDLMLFLEAEQGVTHITEDIC--------LDIIRRYELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVAQD-MTQPLSHYYINASHNTYLIEDQFRGPADINGYIRALKMGCRSVELDVS--DGSDNEPILCNRN---------------NMTTHVSFRSVIEVINKFAFVASEYPLILCLGNHCS-LPQQKVMAQQMKKVFGNKLYTEAPLPS-----ESYLPSPEKLKRMIIVKGKKLPSDPDVLEGEVTDEDE-----------------------------------------------------------------------------EAEMS-------------------RRMSVDYNGEQ------------------------------------------KQIRLCRELSDLVSICKS--VQYRDFELSMKSQN--------------------YWEMCSFSETEASRIANEYPE--DFVNYNKKFLSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDLHTGWFLQNGG-------CGYVLRPS---IMRDEVSYFSANTKGILPGVSPLALHIKIISGQNFPKPKG--ACAKGDVIDPYVCIEIHG-------IPADCSEQRTKTVQQ------NSDNPIFDET--FEFQVNLPELAMIRFVVLD-DDYIGD-EFIGQYTIPFECLQPG--YRHVPLRSFVGDIMEHVTLFVHIAITNRSG------------------GGKAQKRSLSVRMGKKV-REYTMLRNIGLKTIDDIFKIAVHPLREAIDMR--------------------ENMQNAIVSIKELCG----------------------------------------LPPIASLKQCLLTLSSRLITSDNTPSVSLVMKDSFPYLEPLGAIPDVQKKMLTAYDLMIQESR----------------------------------------------------------------------------------------------------------------------------------------------------------FLIEMADTVQEKIVQCQKAGMEFHEELHNLGAKEGLKGRKLNKATES--------------FAWNITVLKGQGDLLKNAKNEAIENMKQIQLACLSCGLSK-APSSSAEAKSKRSLEAIEEKESSEENGKL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K394-1", "uniprot_id": "PLCL2_MOUSE", "id": "Q8K394-1", "name": "Inactive phospholipase C-like protein 2", "aln": "------------MAECGRG-AAGGALPTSPSPALGAKGALKAGAGEGGGGGGGGRLGHGRARYDSGGVSNGDCSLGVSGDEARTSPGRGPLGVALARTPSPAAGPVPRDSKPGGLPRRSSIIKDGTKQKRE--RKKTVSFSSMPTEKKISS---------------------------------ASDCINSMVEGSELKKVRSNS-------RIYHRYFLLDADMQSLRWEPSKK----DSEKAKIDIKSIKEVRTGKNTDIFRSN--------GISEQISEDCAFSVIYGE---NYESLDLVANSADVANIWVTGLRYLISYGKHTLDMLESSQ--------DNMRTSWISQMFSEIDV-------DGLGHITLCHAVQCIRNLNPGLKTSKIELKFKELHKSKDKAGTEITKEEFIEVFHELCTRPEIYFLLVQ----------FSSNKE--FLDTKDLMMFLEAEQGVAHINEEIS--------LEIIHKYEPSKEGQEKGWLSIDGFTNYLMSPDCYIFDPEHKKVCQD-MKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALKMGCRSVELDVW--DGPDNEPVIYTGH---------------TMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCS-IKQQKVMVQHMKKILGDKLYTTSPNME-----ESYLPSPDVLKGKILIKAKKLSSNCSGVEGDVTDEDE-----------------------------------------------------------------------------GAEMS-------------------QRMGKENVEQPNHVPV-------------------------------------KRFQLCKELSELVSICKS--VQFKEFQVSFQVQK--------------------YWEVCSFNEVLASKYANENPG--DFVNYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNVGWFRQNGN-------CGYVLRPA---IMREEVSFFSANTKDSVPGVSPQLLHIKIISGQNFPKPKG--SGAKGDVVDPYVYVEIHG-------IPADCAEQRTKTVNQ------NGDAPIFDES--FEFQINLPELAMVRFVVLD-DDYIGD-EFIGQYTIPFECLQTG--YRHVPLQSLTGEVLAHASLFVHVAITNRRG------------------GGKPHKRGLSVRKGKKS-REYASLRTLWIKTVDEVFKNAQPPIRDATDLR--------------------ENMQNAVVSFKELCG----------------------------------------LSSVANLMQCMLAVSPRFLGPDNNPLVVLNLSEPYPTMELQAIVPEVLKKIVTTYDMMMQSLK----------------------------------------------------------------------------------------------------------------------------------------------------------ALIENADAVYEKIVHCQKAAMEFHEHLHSIGTKEGLKERKLQKAVES--------------FTWNITILKGQADLLKYAKNETLENLKQIHFAAVSCGLNKPGTENSEAQKPRRSLEAIPEKAS-DENGD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M324-1", "uniprot_id": "F1M324_RAT", "id": "F1M324-1", "name": "Phosphoinositide phospholipase C", "aln": "------------MAECGRG-AAGGALPTSPGPALGAKGALKAGAGEGGGSGGGGRLGHGRARYDSGGVSNGDCSLGVSGDEARASPARGPRGVALARTPSPAAGPVPRDSKPGGLPRRSSIIKDGTKQKRE--RKKTVSFSSMPTEKKISS---------------------------------ASDCINSMVEGSELKKVRSNS-------RIYHRYFLLDADMQSLRWEPSKK----DSEKAKIDIKSIKEVRTGKNTDIFRSN--------GISEQISEDCAFSVIYGE---NYESLDLVANSADVANIWVTGLRYLISYGKHTLDMLESSQ--------DNMRTCWVSQMFSEIDV-------DDLGHITLCNAVQCIRNLNPGLKTSKIELKFKELHKSKDKTGTEITKEEFVEVFHELCTRPEIYFLLVQ----------FSSNKE--FLDTKDLMMFLEAEQGVAHINEEIS--------LEIIHKYEPSKEGQEKGWLSIDGFTNYLMSPDCYIFDPEHKKVCQD-MKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALKMGCRSVELDVW--DGPDNEPVIYTGH---------------TMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCS-IKQQKVMVQHMKKILGDKLYTTSPNME-----ESYLPSPDVLKGKILIKAKKLSSNCSGVEGDVTDEDE-----------------------------------------------------------------------------GAEMS-------------------QRMGKENVEQPNHVPV-------------------------------------KRFQLCKDLSELVSICKS--VQFKEFQVSFQVQK--------------------YWEVCSFNEVLASKYANENPG--DFVNYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNIGWFRQNGN-------CGYVLRPA---IMREEVSFFSANTKDSVPGVSPQLLHIKIISGQNFPKPKG--SGAKGDVVDPYVYVEIHG-------IPADCAEQRTKTVNQ------NGDAPMFDES--FEFQINLPELAMVRFVVLD-DDYIGD-EFIGQYTIPFECLQTG--YRHVPLQSLTGEVLAHASLFVHVAITNRRG------------------GGKPHKRGLSVRKGKKS-REYASLRTLWIKTVDEVFKNAQPPIRDATDLR--------------------ENMQNAVVSFKELCG----------------------------------------LSSVANLMQCMLAVSPRFLGPDNTPLVVLNLSEPYPTMELQAIVPEVLKKIVTTYDMMIQSLK----------------------------------------------------------------------------------------------------------------------------------------------------------ALIENADAVYEKIVHCQKAAMEFHEHLHSIGTKEGLKERKLQKAVES--------------FTWNITILKGQADLLKYAKNETLENLKQIHYAAVSCGLNKPGTENSEAQKPRRSLEVIPEKTS-DENGD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UPR0-1", "uniprot_id": "PLCL2_HUMAN", "id": "Q9UPR0-1", "name": "Inactive phospholipase C-like protein 2", "aln": "------------MAECGRGGAAGGALPTSPGPALGAKGALKAGVGEGG--GGGGRLGHGRARYDSGGVSNGDCSLGVSGDEARASPTRGPRGVALAPTPSAVVCTLPRESKPGGLPRRSSIIKDGTKQKRE--RKKTVSFSSMPTEKKISS---------------------------------ASDCINSMVEGSELKKVRSNS-------RIYHRYFLLDADMQSLRWEPSKK----DSEKAKIDIKSIKEVRTGKNTDIFRSN--------GISDQISEDCAFSVIYGE---NYESLDLVANSADVANIWVTGLRYLISYGKHTLDMLESSQ--------DNMRTSWVSQMFSEIDV-------DNLGHITLCNAVQCIRNLNPGLKTSKIELKFKELHKSKDKAGTEVTKEEFIEVFHELCTRPEIYFLLVQ----------FSSNKE--FLDTKDLMMFLEAEQGVAHINEEIS--------LEIIHKYEPSKEGQEKGWLSIDGFTNYLMSPDCYIFDPEHKKVCQD-MKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALKMGCRSVELDVW--DGPDNEPVIYTGH---------------TMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCS-IKQQKVMVQHMKKLLGDKLYTTSPNVE-----ESYLPSPDVLKGKILIKAKKLSSNCSGVEGDVTDEDE-----------------------------------------------------------------------------GAEMS-------------------QRMGKENMEQPNNVPV-------------------------------------KRFQLCKELSELVSICKS--VQFKEFQVSFQVQK--------------------YWEVCSFNEVLASKYANENPG--DFVNYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNIGWFRQNGN-------CGYVLRPA---IMREEVSFFSANTKDSVPGVSPQLLHIKIISGQNFPKPKG--SGAKGDVVDPYVYVEIHG-------IPADCAEQRTKTVHQ------NGDAPIFDES--FEFQINLPELAMVRFVVLD-DDYIGD-EFIGQYTIPFECLQTG--YRHVPLQSLTGEVLAHASLFVHVAITNRRG------------------GGKPHKRGLSVRKGKKS-REYASLRTLWIKTVDEVFKNAQPPIRDATDLR--------------------ENMQNAVVSFKELCG----------------------------------------LSSVANLMQCMLAVSPRFLGPDNTPLVVLNLSEQYPTMELQGIVPEVLKKIVTTYDMMIQSLK----------------------------------------------------------------------------------------------------------------------------------------------------------ALIENADAVYEKIVHCQKAAMEFHEHLHSIGTKEGLKERKLQKAVES--------------FTWNITILKGQADLLKYAKNETLENLKQIHFAAVSCGLNKPGTENADVQKPRRSLEVIPEKAN-DETGE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QKN6-1", "uniprot_id": "A0A8M1QKN6_DANRE", "id": "A0A8M1QKN6-1", "name": "Phosphoinositide phospholipase C", "aln": "------------MSESYEDGVCGDGAPDFIPPR---------------------ALRSGRRS-------------GVAVP----LVERDEAALLESVKAA---------------PRRSSIIKDPSVAKVSGGRKKTVSFSSMPSEKKVSS---------------------------------AADCLAFMQGGCELKKVRPNS-------RIYSRFYTLDTELGCLRWEPSKK----DGDRARLDISAIREVRTGKSTETFIHN--------GPLDNLAEEAAFSIIHGD---DYQSLDLVALSADVANIWVTGMRYLLSHPGAIGGGIGGDGGVGEGSIGSKMRRNWLVAEFALVDE-------DGHGIVSEDTAVATICKLCPGIKEAKVRLRFKEIQRSKEKLTSHVTLEEFQEAYCELCTRPDVYFLLVQ----------LSKDRE--CLDAQDLRLFLESEQGLSMATTEGC--------LELLRLFEPSAAGRERGLLGLDGFARYLQSAECQLLDPEHQNVCQD-MKMPLSHYFISASYRSYLLDDQVHGRADLGGLTRALQAGCRCLELGVT--DGPEGEPLLGVDHGAEVKHHHHHHHHHHHHHGSVTLRSALEVVNKYAFLTSQYPLLLYLCQRCS-PSQQRTLAQHLKKVFGPKLYTPESLPVSLGGRATTLPSPEQLKGKVLLVGKKLPPEEEGSEGEVSEEDEEI------------------------------------------------------------------------GGGGPLAG-------------------RRMTIPGEEELGVVLVV------------------------------PPPPQPRRLRLRHELSDLVAVARTGSRNFYAHRASILPSQQHSPPSTPSTPGTPLNIDPSYWTLCSLGEGEAGRLASESPE--ELVSFTKRNLTRVRPSSVRLDSSNPNPQGYWKGGVQLVALNQQTPGAMLDLNRGRFMQNGG-------CGYVLRPA---VMREEVSYFSAQSQGCVPGVPPQTLRVKVISAHSLPKPQG--SGAKGEVIDPYVVLELHG-------VPADCTEQRTRTAAQ------NQDDPLFDET--FEFQVNMPELALLRFVVLD-DDYIGD-DFIGQYTIAFECLQPG--YRNVPLLGLAGDPLPHASLFIHIAITNRRG------------------GGKAQRRGLSVRRGVRRGREYVTLRNTGIKVLDDTFRPASGPLREATDLR--------------------EDAMCATVAFKELCG----------------------------------------LPPMATLKQCIQSLATRLQSPDGPPGATLTLKDGYPFLEPAANLTDATRKLLNGYDTMISANK----------------------------------------------------------------------------------------------------------------------------------------------------------QLIENADGVQEKIAQVQKEGMVFHEDLPRLGEKENLKGRKQSKAVES--------------FAWNITVLKGQCDLLRSAKIDALDTLRQLALACEASGLIVTSDGQ------YTSHGLSSRRGSSHGNGRI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8K4D7-1", "uniprot_id": "PLCZ1_MOUSE", "id": "Q8K4D7-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MESQLHELAEARWFLS----------------------------------------KVQDD-------FRGGKINVEITHKLLEKLDFPCHFAHVKHIFKENDRQ---NQGRITIEEFRAIYRCIVHREEITEIFNT----------YTENRK--ILSENSLIEFLTQEQYEMEIDHSDS--------VEIINKYEPIEEVKGERQMSIEGFARYMFSSECLLFKENCKTVYQD-MNHPLSDYFISSSHNTYLISDQILGPSDIWGYVSALVKGCRCLEIDCW--DGSQNEPIVYHGY---------------TFTSKLLFKTVVQAINKYAFVTSDYPVVLSLENHCS-PGQQEVMASILQSTFGDFLLSDMLEEFPDT-----LPSPEALKFKILVKNRKVGTLSETHERIGTDKSGQVLEWKEVIY----------------------------------------------------------------EDGDEDSGMDPETWDVFLSRIKEEREADPSTLSGIAGVKKRK--------------------------------------RKMKIAMALSDLVIYTKAEKFRNFQYSRVYQQFN----------------------ETNSIGESRARKLSKLRVH--EFIFHTAAFITRVYPKMMRADSSNFNPQEFWNVGCQMVALNFQTPGLPMDLQNGKFLDNGG-------SGYILKPD---ILRDTTLGFNPNEPEY--DDHPVTLTIRIISGIQLPVS------SSSNTPDIVVIIEVYG-------VPNDHVKQQTRVVKN------NAFSPKWNET--FTFLIQVPELALIRFVVETQQGLLSGNELLGQYTLPVLCMNKG--YRRVPLFSKSGANLEPSSLFIYVWYFRE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5FX52-1", "uniprot_id": "PLCZ1_RAT", "id": "Q5FX52-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MESH-YELAEARWFMS----------------------------------------KIQDY-------FRGGKISAGITHKLLEKLDFPCHFAHVKRIFKENDRH---NQGRITTEDFRTIYRCIVHREEIVEIFNT----------YTENRK--ILPEDSLIEFLTQEQYEMEMDESSS--------VEIIQKYEPIAEVKNERQMSIEGFARYMFSSECLLFKETCNTVYQD-MNKPLNDYYISSSHNTYLISDQILGPSDIWGYISALVKGCRCLEIDCW--DGAQNEPIVYHGY---------------TLTSKLLFKTVIQAINKYAFVTSDYPVVLSLENHCS-PGQQEVMTDILQSTFGDFLLSDILDEFPDS-----LPSPEALKFKILVKNKKVGTLSETRERLGTDKRGIALDLEEEIY----------------------------------------------------------------ENEDEDSGKEPETWDDFLSRVKEEQEADPSTLSGIADAKKKI--------------------------------------RKLRVALALSDLVIYTKAEKFRNFQYSRVYQQFN----------------------ETTSMGESRARKLSKLRAH--EFIFHTAAFITRVYPKFTRADSSNFNPQEFWNVGCQMVALNFQTPGLPMDLQNGKFLDNGG-------SGYVLKPD---FLRDTTLGFNPNEPEG--DGHPVTLTIRLISGIQLPVN------VPSNTSDIIVIIEVYG-------VPNDHMKQQSRAVKN------NAFSPRWNET--FTFLIQVPELALIRFVVET-QGFLSGNELLGQYTLPVLCMNKG--YRRVPLFSKSGANLEPSSLFIYVWYYRE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86YW0-1", "uniprot_id": "PLCZ1_HUMAN", "id": "Q86YW0-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEMRWFLS----------------------------------------KIQDD-------FRGGKINLEKTQRLLEKLDIRCSYIHVKQIFKDNDRL---KQGRITIEEFRAIYRIITHREEIIEIFNT----------YSENRK--ILLASNLAQFLTQEQYAAEMSKAIA--------FEIIQKYEPIEEVRKAHQMSLEGFTRYMDSRECLLFKNECRKVYQD-MTHPLNDYFISSSHNTYLVSDQLLGPSDLWGYVSALVKGCRCLEIDCW--DGAQNEPVVYHGY---------------TLTSKLLFKTVIQAIHKYAFMTSDYPVVLSLENHCS-TAQQEVMADNLQATFGESLLSDMLDDFPDT-----LPSPEALKFKILVKNKKIGTLKETHERKGSDKRG--------------------------------------------------------------------------DNQDKETGVKK--------------------LPGVMLFKKKKT-------------------------------------RKLKIALALSDLVIYTKAEKFKSFQHSRLYQQFN----------------------ENNSIGETQARKLSKLRVH--EFIFHTRKFITRIYPKATRADSSNFNPQEFWNIGCQMVALNFQTPGLPMDLQNGKFLDNGG-------SGYILKPH---FLRESKSYFNPSNIK---EGMPITLTIRLISGIQLPLTH-----SSSNKGDSLVIIEVFG-------VPNDQMKQQTRVIKK------NAFSPRWNET--FTFIIHVPELALIRFVVEG-QGLIAGNEFLGQYTLPLLCMNKG--YRRIPLFSRMGESLEPASLFVYVWYVR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KGF7-1", "uniprot_id": "PLCB2_MOUSE", "id": "A3KGF7-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MSLLNP-----VLLPP-----------------------------------NVKAYLSQGERFIKWDDET------SIASPVILRVDPKGYYLYWTYQNQ------EMEFLDVTSIRDTRFGKFAKIPKSQKLREVFNMDFPDNHFLLKTLTVVSGPDMVDLTFYNFVSYKENVGKDWAEDVLALAKHPMTVNAPR-----------STFLDKILVKLKMQLNPE-------GKIPVKNFFQMFP---ADRKRVEAALGACHLAKGKNDA-INPEDFPESVYKSFLMSLCPRPEIDEIFTS----------YHSKAK-PYMTKEHLTKFINQKQRDPRLNSLLFPPARPEQVQVLIDKYEPSGINVQRGQLSPEGMVWFLCGPENSVLAHDTLLIHQD-MTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGF---------------TMTTDILFKEAIEAIAESAFKTSPYPVILSFENHVDSPRQQAKMAEYCRSMFGETLLTDPLENFPLKP-GIPLPSPEDLRGKILIKNKKNQFSGP----ASPSKKPGGV----AEGSLPSSVPVEEDTGWTAEDRTEVEE----------------------------------------EEVVEEEEEEE----------------SGNLDEEEIKKMQSD---------------------------------EGTAGLEVTAYEEMSSLVNYIQPTKFISFEFSAQKNRSY----------------------VVSSFTELKAYELLSKASM--QFVDYNKRQMSRVYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQ-------SGYLLKHE---FMRRLDKQFNPFSVDRIDVVVATTLSITIISGQFLSERS----------VRTYVEVELFG-------LPGDPKRR-YRTKLSP---TANSINPVWKEEPFIFEKILMPELASLRIAVME-----EGSKFLGHRIIPINALHSG--YHHLCLRSESNMALTMPALFVFLEMKDYIP----------------------DTWADLTVALANPIKYFNAQDKKSVKLKGVTG-----------------------------------SLPEKLFS-GTPVASQSNGAP--------------------VSAGNGSTAPGTKATGEEATKEVTEPQTASLEELRELKGVVKLQRRHEKELRELERRGARRWEELLQRGAAQLAELQT----QAAG----CKLRPGKGSRKKRT-------------------------------------------------------------------------------------------------------------------LPCEETV-VAPSEPHDRADPRVQELKDRLEQELQQQGEEQYRSVLKRKEQHVTEQIAKMMELAREK-QAAELKTFKETSETDTKEMKKKLEAKRLERIQAMTK--VTTDKVAQERLKREINNSHIQEVVQAVKQMTETLER---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HQEKLEERQTACLEQIQAMEKQFQEKALAEYEAK----MKGLEAEVKESVRAYFKDCFPTEAEDK------PERSCEASEESCPQEPLVSKADTQE--SRL-----------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O89040-1", "uniprot_id": "PLCB2_RAT", "id": "O89040-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MSLLNP-----VLLPP-----------------------------------KVKAYLSQGERFIKWDDET------SIASPVILRVDPKGYYLYWTHQSK------EMEFLDVTSIRDTRFGKFAKIPKSQKLREVFNMDFPDNHFLLKTFTVVSGPDMVGLTFHNFVSYKENVGKDWAEDVLALAKHPMTANASR-----------STFLDKILVKLKMQLSPE-------GKIPVKNFFQMFP---ADRKRVEAALSACHLAKGKNDA-INPEDFPESVYKSFLMSLCPRPEIDEIFTS----------YHAKAK-PYMTKEHLTKFINQKQRDPRLNSLLFPPARPEQVQALIDKYEPSGINVQRGQLSPEGMVWFLCGPENSVLAHDTLRIHQD-MTQPLNHYFINSSHNTYLTAGQFSGPSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGF---------------TMTTDILFKEAVEAIAESAFKTSPYPVILSFENHVDSPRQQAKMAEYCRTMFGETLLTEPLENFPLKP-GMPLPSPEDLRGKILIKNKKNQFSGP----ASPNKKPDGV----SEGGFPSSVPVEEDTGWTAEDRTEVEEGE-------------------------------------EEEEVEEEEEEE----------------SGNLDEEEIKKMQSD---------------------------------EGTAGLEVTAYEEMSSLVNYIQPTKFISFEFSAQKNRSY----------------------LVSSFTELKAYELLSKASM--QFVDYNKRQMSRVYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQ-------SGYLLKHE---FMRRQDKQFNPFSVDRIDVVVATTLSITVISGQFLSERS----------VRTYVEVELFG-------LPGDPKRR-YRTKLSP---TANSINPVWKEEPFIFEKILVPELASLRIAVME-----EGGKFIGHRIIPINALHSG--YHHLCLRSESNMPLTMPALFVFLEMKDYVP----------------------DTWADLTVALANPIKYFSAHDKKSVKLKEVTG-----------------------------------SLPEKLFS-GIPVASQSNGAP--------------------VSAGNGSTAPGTKAK-EEATKEVAEPQTTSLEELRELKGVVKLQRRHEKELRELERRGARRWEELLQRGAAQLAELQD----PAAS----CKLRPGKGSRKKRI-------------------------------------------------------------------------------------------------------------------VPCEETI-VVPREVLEGPDPRVQDLKDRLEQELQQQGEEQYRSVLKRKEQHVTEQIAKMMELAREK-QAAELKSFKETSETDTKEMKKKLEAKRLERIQAMTK--VTTDKVAQERLKREINNSHIQEVVQAVKQMTETLER---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HQEKLEEKQTACLEQIQAMEKQFQEKALAEYEAK----MKGLEAEVKESMRACFKACFPTEAEEK------PERPCEASEESCPQEPLVNKTDTQE--SRL-----------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00722-1", "uniprot_id": "PLCB2_HUMAN", "id": "Q00722-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MSLLNP-----VLLPP-----------------------------------KVKAYLSQGERFIKWDDET------TVASPVILRVDPKGYYLYWTYQSK------EMEFLDITSIRDTRFGKFAKMPKSQKLRDVFNMDFPDNSFLLKTLTVVSGPDMVDLTFHNFVSYKENVGKAWAEDVLALVKHPLTANASR-----------STFLDKILVKLKMQLNSE-------GKIPVKNFFQMFP---ADRKRVEAALSACHLPKGKNDA-INPEDFPEPVYKSFLMSLCPRPEIDEIFTS----------YHAKAK-PYMTKEHLTKFINQKQRDSRLNSLLFPPARPDQVQGLIDKYEPSGINAQRGQLSPEGMVWFLCGPENSVLAQDKLLLHHD-MTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGF---------------TMTTDIFFKEAIEAIAESAFKTSPYPIILSFENHVDSPRQQAKMAEYCRTIFGDMLLTEPLEKFPLKP-GVPLPSPEDLRGKILIKNKKNQFSGP----TSSSKDTGGE----AEGSSPPSAPAGEGTVWAGEEGTELEE-----------------------------------------EEVEEEEEEE----------------SGNLDEEEIKKMQSD---------------------------------EGTAGLEVTAYEEMSSLVNYIQPTKFVSFEFSAQKNRSY----------------------VISSFTELKAYDLLSKASV--QFVDYNKRQMSRIYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMAVFEFNGQ-------SGYLLKHE---FMRRPDKQFNPFSVDRIDVVVATTLSITVISGQFLSERS----------VRTYVEVELFG-------LPGDPKRR-YRTKLSP---STNSINPVWKEEPFVFEKILMPELASLRVAVME-----EGNKFLGHRIIPINALNSG--YHHLCLHSESNMPLTMPALFIFLEMKDYIP----------------------GAWADLTVALANPIKFFSAHDTKSVKLKEAMG-----------------------------------GLPEKPFPLASPVASQVNGAL--------------------APTSNGSPAARAGAR-EEAMKEAAEPRTASLEELRELKGVVKLQRRHEKELRELERRGARRWEELLQRGAAQLAELGP----PGVGGVGACKLGPGKGSRKKRS-------------------------------------------------------------------------------------------------------------------LPREESAGAAPGEGPEGVDGRVRELKDRLELELLRQGEEQYECVLKRKEQHVAEQISKMMELAREK-QAAELKALKETSENDTKEMKKKLETKRLERIQGMTK--VTTDKMAQERLKREINNSHIQEVVQVIKQMTENLER---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HQEKLEEKQAACLEQIREMEKQFQKEALAEYEAR----MKGLEAEVKESVRACLRTCFPSEAKDK------PERACECPPELCEQDPLIAKADAQE--SRL-----------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P51432-1", "uniprot_id": "PLCB3_MOUSE", "id": "P51432-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MAGARPGVHALQLEPP-----------------------------------TVVETLRRGSKFIKWDEEA------SSRNLVTLRVDPNGFFLYWTGPNM------EVDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDTRLEEKLMTVVAGPDPVNTTFLNFMAVQDDTVKVWSEELFKLAMNILAQNASR-----------NTFLRKAYTKLKLQVNQD-------GRIPVKNILKMFS---ADKKRVETALESCGLNFNRSES-IRPDEFPLEIFERFLNKLCLRPDIDKILLE----------IGAKGK-PYLTLEQLMDFINQKQRDPRLNEVLYPPLRSSQARLLIEKYETNKQFLERDQMSMEGFSRYLGGEENGILPLEALDLSMD-MTQPLSAYFINSSHNTYLTAGQLAGPSSVEMYRQALLWGCRCVELDVWKGRPPEEEPFITHGF---------------TMTTEVPLRDVLEAIAEAAFKTSPYPVILSFENHVDSAKQQAKMAEYCRSIFGDALLIDPLDKYPLSA-GIPLPSPQDLMGRILVKNKKRHRPSTGVPDSSVRKRPLEQ----SNSALSESSAATEPSSPQLGSPSSDSCPGLSNGEEVGLEKTSLEPQKSLGEESLSREPN-----VPMPDRDREDEEED----------------EEEEETTDPKKPTTD---------------------------------EGTASSEVNATEEMSTLVNYVEPVKFKSFEAARKRNKCF----------------------EMSSFVETKAMEQLTKSPM--EFVEYNKQQLSRIYPKGTRVDSSNYMPQLFWNVGCQLVALNFQTLDLPMQLNAGVFEYNGR-------SGYLLKPE---FMRRPDKSFDPFTEVIVDGIVANALRVKVISGQFLSDKK----------VGIYVEVDMFG-------LPVDTRRK-YRTRTS----QGNSFNPVWDEEPFDFPKVVLPTLASLRIAAFE-----EGGKFVGHRILPVSAIRSG--YHYVCLRNEANQPLCLPALLIYTEASDYIP----------------------DDHQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQASTETYQET--------------------PCQQPGSQLPSNPTPNPLDASPRWPPGP--------------TTSSTSSSLSSPGQRDDLIASILSEVTPTPLEELRSHKAMVKLRSRQDRDLRELHKKHQRKAVALT-----------------RRLLDGLAQARAEGKCRPSPS-------------------------------------------------------------------------------------------------------------------ALGKATNSEDVKEEEE--AKQYREFQNRQVQSLLELREAQADVETKRKLEHLRQAHQRLKEVVLDT-HTTQFKRLKELNEREKKELQKILDRKRNNSISEAK----TREKHKKEVELTEINRRHITESVNSIRRLEEAQKQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHERLVAGQQQVLQQLEEEEPKLLAQLTQECQEQ----RERLPQEIRR----CLLGETAEGLGDG----PLVACASNGHAPGSGGHLSSADSESQEENTQL-----------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99JE6-1", "uniprot_id": "PLCB3_RAT", "id": "Q99JE6-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MAGARPGVHALQLEPP-----------------------------------TVVETLRRGSKFIKWDEEA------SSRNLVTLRLDPNGFFLYWTGPNM------EVDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDTRLEEKLMTVVAGPDPVNTTFLNFMAVQDDTVKVWSEELFKLAMNILAQNAP------------EHVLRKAYTKLKLQVNQD-------GRIPVKNILKMFS---ADKKRVETALI-CGLNFNRSES-IRPDEFSLEIFERFLNKLLLRPDIDKILLE----------IGAKGK-PYLTLEQLMDFINQKQRDPRLNEVLYPPLRSSQARLLIEKYEPNKQFLERDQMSMEGFSRYLGGEENGILPLEALDLSMD-MTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRCVELDVWKGRPPEEEPFITHGF---------------TMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAKQQAKMAEYCRSIFGEALLIDPLDKYPLSA-GTPLPSPQDLMGRILVKNKKRHRPSTGVPDSSVAKRPLEQ----SNSALSESSAATEPSSPQLGSPSSDSCPGLSNGEEVGLEKTSLEPQKSLGEEGLNRGPN-----VLMPDRDREDEEED----------------EEEEETTDPKKPTTD---------------------------------EGTASSEVNATEEMSTLVNYVEPVKFKSFEASRKRNKCF----------------------EMSSFVETKAMEQLTKSPM--EFVEYNKQQLSRIYPKGTRVDSSNYMPQLFWNVGCQLVALNFQTLDLPMQLNAGVFEYNGR-------SGYLLKPE---FMRRPDKSFDPFTEVIVDGIVANALRVKVISGQFLSDRK----------VGIYVEVDMFG-------LPVDTRRK-YRTRTS----QGNSFNPVWDEEPFDFPKVVLPTLASLRIAAFE-----EGGRFVGHRILPVSAIRSG--YHYVCLRNEANQPLCLPALLIYTEASDYIP----------------------DDHQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQASTEMCQET--------------------PSQQQGSQLSSNPVPNPLDDSPRWPPGP--------------TTSPTSTSLSSPGQRDDLIASILSEVTPTPLEELRSHKAMVKLRSRQDRDLRELHKKHQRKAVALT-----------------RRLLDGLAQARAEGKCRPSSS-------------------------------------------------------------------------------------------------------------------ALSRATNVEDVKEEEKEAARQYREFQNRQVQSLLELREAQADAETERRLEHLKQAQQRLREVVLDA-HTTQFKRLKELNEREKKELQKILDRKRNNSISEAK----TREKHKKEVELTEINRRHITESVNSIRRLEEAQKQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHERLLAGQQQVLQQLVEEEPKLVAQLTQECQEQ----RERLPQEIRR----CLLGETSEGLGDG----PLVACASNGHAAGSGGHQSGADSESQEENTQL-----------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01970-1", "uniprot_id": "PLCB3_HUMAN", "id": "Q01970-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MAGAQPGVHALQLEPP-----------------------------------TVVETLRRGSKFIKWDEET------SSRNLVTLRVDPNGFFLYWTGPNM------EVDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDARLEEKLMTVVSGPDPVNTVFLNFMAVQDDTAKVWSEELFKLAMNILAQNASR-----------NTFLRKAYTKLKLQVNQD-------GRIPVKNILKMFS---ADKKRVETALESCGLKFNRSES-IRPDEFSLEIFERFLNKLCLRPDIDKILLE----------IGAKGK-PYLTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKYEPNQQFLERDQMSMEGFSRYLGGEENGILPLEALDLSTD-MTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRCVELDVWKGRPPEEEPFITHGF---------------TMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAKQQAKMAEYCRSIFGDALLIEPLDKYPLAP-GVPLPSPQDLMGRILVKNKKRHRPSAGGPDSAGRKRPLEQ----SNSALSESSAATEPSSPQLGSPSSDSCPGLSNGEEVGLEKPSLEPQKSLGDEGLNRGPY-----VLGP-ADREDEEED----------------EEEEEQTDPKKPTTD---------------------------------EGTASSEVNATEEMSTLVNYIEPVKFKSFEAARKRNKCF----------------------EMSSFVETKAMEQLTKSPM--EFVEYNKQQLSRIYPKGTRVDSSNYMPQLFWNVGCQLVALNFQTLDVAMQLNAGVFEYNGR-------SGYLLKPE---FMRRPDKSFDPFTEVIVDGIVANALRVKVISGQFLSDRK----------VGIYVEVDMFG-------LPVDTRRK-YRTRTS----QGNSFNPVWDEEPFDFPKVVLPTLASLRIAAFE-----EGGKFVGHRILPVSAIRSG--YHYVCLRNEANQPLCLPALLIYTEASDYIP----------------------DDHQDYAEALINPIKHVSLMDQRARQLAALIGESEAQAGQETCQDT--------------------QSQQLGSQPSSNPTPSPLDASPRRPPGP--------------TTSPASTSLSSPGQRDDLIASILSEVAPTPLDELRGHKALVKLRSRQERDLRELRKKHQRKAVTLT-----------------RRLLDGLAQAQAEGRCRLRPG-------------------------------------------------------------------------------------------------------------------ALGGAADVEDTKEGEDE-AKRYQEFQNRQVQSLLELREAQVDAEAQRRLEHLRQALQRLREVVLDA-NTTQFKRLKEMNEREKKELQKILDRKRHNSISEAK----MRDKHKKEAELTEINRRHITESVNSIRRLEEAQKQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHDRLVAGQQQVLQQLAEEEPKLLAQLAQECQEQ----RARLPQEIRR----SLLGEMPEGLGDG----PLVACASNGHAPGSSGHLSGADSESQEENTQL-----------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z1B3-1", "uniprot_id": "PLCB1_MOUSE", "id": "Q9Z1B3-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MAGAQPGVHALQLKPV-----------------------------------CVSDSLKKGTKFVKWDDDS------TIVTPIILRTDPQGFFFYWTDQNK------ETELLDLSLVKDARCGKHAKAPKDPKLRELLDVGN-IGHLEQRMITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSR-----------DAFLEKAYTKLKLQVTPE-------GRIPLKNIYRLFS---ADRKRVETALEACSLPSSRNDS-IPQEDFTPDVYRVFLNNLCPRPEIDNIFSE----------FGAKSK-PYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNSSLAKKGQMSVDGFMRYLSGEENGVVSPEKLDLNED-MSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGF---------------TMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLES-GVPLPSPMDLMYKILVKNKKKSHKSS---EGSGKKKLSEQ----ASNTYSDSSSVFEPSSPGAG----------------------------------------------------EADTES----------------DDDDDDDDCKKSSMD---------------------------------EGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNKSF----------------------EMSSFVETKGLEQLTKSPV--EFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQINMGMYEYNGK-------SGYRLKPE---FMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKK----------VGTYVEVDMFG-------LPVDTRRKAFKTKTS----QGNAVNPVWEEEPIVFKKVVLPSLACLRIAAYE-----EGGKFIGHRILPVQAIRPG--YHYICLRNERNQPLTLPAVFVYIEVKDYVP----------------------DTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGE--------------------TSSEAPSETRTTPAENGVNHTASLAPKPPSQA---------PHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTELIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEPSSP-------------------------------------------------------------------------------------------------------------------DHGSSAIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEEC-QNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAK----SKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RQEKLVEKHNEIRQQILDEKPKLQTELEQEYQDK----FKRLPLEILEFVQEAMKGKISEDSNHGSAPPSLASDAAKVNLKSPSSEEIERENPGREFDTPL-----------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10687-1", "uniprot_id": "PLCB1_RAT", "id": "P10687-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MAGAQPGVHALQLKPV-----------------------------------CVSDSLKKGTKFVKWDDDS------TIVTPIILRTDPQGFFFYWTDQNK------ETELLDLSLVKDARCGKHAKAPKDPKLRELLDVGN-IGHLEQRMITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSR-----------DAFLEKAYTKLKLQVTPE-------GRIPLKNIYRLFS---ADRKRVETALEACSLPSSRNDS-IPQEDFTPDVYRVFLNNLCPRPEIDNIFSE----------FGAKSK-PYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNSSLAKKGQMSVDGFMRYLSGEENGVVSPEKLDLNED-MSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGF---------------TMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLES-GVPLPSPMDLMYKILVKNKKKSHKSS---EGSGKKKLSEQ----ASNTYSDSSSVFEPSSPGAG----------------------------------------------------EADTES----------------DDDDDDDDCKKSSMD---------------------------------EGTAGSEAMATEEMSNLVNYIQPVKFESFETSKKRNKSF----------------------EMSSFVETKGLEQLTKSPV--EFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQINMGMYEYNGK-------SGYRLKPE---FMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKK----------VGTYVEVDMFG-------LPVDTRRKAFKTKTS----QGNAVNPVWEEEPIVFKKVVLPSLACLRIAAYE-----EGGKFIGHRILPVQAIRPG--YHYICLRNERNQPLMLPAVFVYIEVKDYVP----------------------DTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGE--------------------TSSEAPSETRTTPAENGVNHTATLAPKPPSQA---------PHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTELIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEPSSP-------------------------------------------------------------------------------------------------------------------DHGSSAIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEEC-QNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAK----SKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RQEKLVEKHKEIRQQILDEKPKLQMELEQEYQDK----FKRLPLEILEFVQEAMKGKVSEDSNHGSAPPSLASDPAKVNLKSPSSEEVQGENAGREFDTPL-----------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQ66-1", "uniprot_id": "PLCB1_HUMAN", "id": "Q9NQ66-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MAGAQPGVHALQLKPV-----------------------------------CVSDSLKKGTKFVKWDDDS------TIVTPIILRTDPQGFFFYWTDQNK------ETELLDLSLVKDARCGRHAKAPKDPKLRELLDVGN-IGRLEQRMITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSR-----------DAFLEKAYTKLKLQVTPE-------GRIPLKNIYRLFS---ADRKRVETALEACSLPSSRNDS-IPQEDFTPEVYRVFLNNLCPRPEIDNIFSE----------FGAKSK-PYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEKLDLNED-MSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGF---------------TMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLES-GVPLPSPMDLMYKILVKNKKKSHKSS---EGSGKKKLSEQ----ASNTYSDSSSMFEPSSPGAG----------------------------------------------------EADTES----------------DDDDDDDDCKKSSMD---------------------------------EGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNKSF----------------------EMSSFVETKGLEQLTKSPV--EFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGK-------SGYRLKPE---FMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKK----------VGTYVEVDMFG-------LPVDTRRKAFKTKTS----QGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYE-----EGGKFIGHRILPVQAIRPG--YHYICLRNERNQPLTLPAVFVYIEVKDYVP----------------------DTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGE--------------------TPSEAPSEARTTPAENGVNHTTTLTPKPPSQA---------LHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEPSSP-------------------------------------------------------------------------------------------------------------------DHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEEC-QNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAK----SKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RQEKLVEKHKEIRQQILDEKPKLQVELEQEYQDK----FKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEELGGDIPGKEFDTPL-----------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25455-3", "uniprot_id": "PIP1_DROME", "id": "P25455-3", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MMSAGGTYISTASV-----------------------------------EVPQALQDGEKFIRWDDDS------GTGTPVTMRVDAKGFFLYWVDQNN------ELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLGP-QDTLEEKTVTVCHGSDFVNMTFVNFCCTRRDIAQLWTDGLIKLAYSLAQLNGSA-----------IMFLQKAHTKLCLQVDKS-------GRIPVKNIIKLFAQNKEDRKRVEKALDVTGLPSGKVDS-ISVSKFQFEDFYNLYKYLTQRSEVERLFDS----------IVGNSKRKCMSIAQLVEFLNKTQRDPRLNEILYPYANPARAKELIQQYEPNKFNAQKGQLSLDGFLRYLMGDDNPIMAPSKLDLCDD-MDQPMSHYFINSSHNTYLTGHQLTGKSSVEIYRQCLLAGCRCVELDFWNGRT--EEPVIVHGY---------------TFVPEIFAKDVLEAIAESAFKTSEYPVILSFENHCN-PRQQAKIANYCREIFGDMLLDKPLDSHPLEP-NMDLPPPAMLRRKIIIKNKKKHHHHH---HHHHHKKPAQVGTPAANNKLTTANSVDAKAAQQVGLSASHEDGGVTRSTANGDVATGTGTGSAAGTAGHAPPLQ-----QIRQSSKDSTGSSD----------------SDSSSEDESLPNTTPNL------------------------PSGNEPPPEKAQKETEAGAEISALVNYVQPIHFSSFENAEKKNRCY----------------------EMSSFDEKQATTLLKERPI--EFVNYNKHQLSRVYPAGTRFDSSNFMPQLFWNAGCQLVALNFQTLDLAMQLNLGIFEYNAR-------SGYLLKPE---FMRRSDRRLDPFAESTVDGIIAGTVSITVLSGQFLTDKR----------ANTFVEVDMYG-------LPADTVRKKFRTKTV----RDNGMNPLYDEEPFVFKKVVLPELASIRIAAYE-----EGGKLIGHRVLPVIGLCPG--YRHVNLRSEVGQPIALASLFLCVVVKDYVP----------------------DDLSNFAEALANPIKYQSELEKRDIQLSVLTDEAEALGSADEDLSKSFVFVQVGGQKKELRPVESLATSPKHRPSISAAAAMSVDVTVDRTDGGRGEDSISIVAPSIQHQHSLDQSVSTSIRQVESSQFDVDLVLAEPLEKILDHKSVKEKRLEMEKKLESLRKKHDKEKIKIAGQKSSPLEGKKPKFAITNKLVKRLSNKSLNCLSPHSEPGVEI----------------------------------------------------------------------------------------------------------PACPLDLGDSSEESAAADAGEDLAGGSSSLDGRTQESRLRSACREYTSQYRELQEKYHEAIYSAAEKVLKTSQTGQTKQLKASLDKVTGEVMHQLQEARRNEVKNLAT--VHRDRDELIRMKREVASSVVERGVAERVRLKQTFDR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RTDELQKQHDSVRNALAEHRSKARQILDKEAESRSCVSSNGFLVLFHGPHHHGCTGSGSSALSGNNLTLNLDAGAAGSHSAISPAKSHNSIAAAAEMKT-------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q15147-1", "uniprot_id": "PLCB4_HUMAN", "id": "Q15147-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MAKP---YEFNWQK-----------------------------------EVPSFLQEGAVFDRYEEES-----FVFEPNCLFKVDEFGFFLTWRSEGK------EGQVLECSLINSIRSGAIPKDPKILAALEA--VGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSP-----------MTCLKKHWMKLAFMTNTN-------GKIPVRSITRTFASG-KTEKVIFQALKELGLPSGKNDE-IEPTAFSYEKFYELTQKICPRTDIEDLFKK----------INGDKT-DYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQE-MDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGK---------------AMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCS-KYQQYKMSKYCEDLFGDLLLKQALESHPLEP-GRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDNEEEIESADQEEEAHPEFKFG---------------------------------------NELSADDLGH----------------KEAVANSVKKGLVTVED------------------------EQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHY----------------------NMSSFNESVGLGYLKTHAI--EFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGS-------CGYLLKPD---FMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKK----------IGTYVEVDMYG-------LPTDTIRKEFRTRMV----MNNGLNPVYNEESFVFRKVILPDLAVLRIAVYD-----DNNKLIGQRILPLDGLQAG--YRHISLRNEGNKPLSLPTIFCNIVLKTYVP----------------------DGFGDIVDALSDPKKFLSITEKRADQMRAMGIETS-------------------------------DIADVPSDTSKNDKKGKANTAKANVTPQ--------------SSSELRPTTTAALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGG-SNC-------------------------------------------------------------------------------------------------------------------LEMKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINA-HEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EMDQLKKVQLEHLEFLEKQNEQ------AKEMQQ------------------------------------MVKLEAEMDRRPATVV--------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QW07-1", "uniprot_id": "PLCB4_RAT", "id": "Q9QW07-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MAKP---YEFNWQK-----------------------------------EVPSFLQEGAVFDRYEEES-----FVFEPNCLFKVDEFGFFLTWKSEGK------EGQVLECSLINSIRLAAIPKDPKILAALES--VGKSENDLEGRILCVCSGTDLVNIGFTYMVAENPEITKQWVEGLRSIIHNFRANNVSP-----------MTCLKKHWMKLAFLTNTS-------GKIPVRSITRTFASG-KTEKVIFQALKELGLPSGKNDE-IEPAAFTYEKFYELTQKICPRTDIEDLFKK----------INGDKT-DYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEELKKKGLISSDGFCRYLMSDENAPVFLDRLELYQE-MDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGK---------------AMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCS-KYQQYQMSKYCEDLFGDLLLKQALESHPLEP-GRLLPSPNDLKRKILIKNKRLKPEVEKKQLEALKSMMEAGESAAPASILEDDNEEEIESADQEEEAHPEYKFG---------------------------------------NELSADDFSH----------------KEAVANSVKKGLVTVED------------------------EQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHY----------------------NMSSFNESVGLGYLKTHAI--EFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGS-------CGYLLKPD---FMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKK----------IGTYVEVDMYG-------LPTDTIRKEFRTRMV----MNNGLNPVYNEESFVFRKVILPDLAVLRIAVYD-----DNNKLIGQRILPLDGLQAG--YRHISLRNEGNKPLSLPTIFCNIVLKTYVP----------------------DGFGDIVDALSDPKKFLSITEKRADQLRAMGIETS-------------------------------DIADVPSDTSKNDKKGKANPAKANVTPQ--------------SSSELRPTTTAALGSGQEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGG-SNC-------------------------------------------------------------------------------------------------------------------LEIKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLRKLLINA-HEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EMDQLKKVQLEHLEFLEKQNEQ------AKEMQQ------------------------------------MVKLEAEMDRRPATVV--------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9PL02-1", "uniprot_id": "A0A8M9PL02_DANRE", "id": "A0A8M9PL02-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase", "aln": "---------------------------------------------------------------------------------------------------------------MYFCVSPQPHSGESQTDYINSSTAGQMAKP---YEFNWQR-----------------------------------PVPQFMQKGACFDRFDEDP-----LVFESNCFFKVDESGFFLTWKSEGK------EGQVLEFSLINSIRDASALKDPKVLCALEA--SGKCESNLEDRIICICSGTDLVNLSFMYMVTQNPTTAKEWTDGLRSLIQNTRANNVCP-----------MTCLRKHWMRLSFLTNVN-------EQIPVRSITRTFASG-KTEKGIFQALKDLGLPSGKNDE-IQREIFTFDKFYSLTQKICPRTDIEVLFKK----------FKGDKG-DYLSVEQFVHFLNDNQRDPRLNEILFPFFNSKCAFQIIQRYEPDEKLKRKGLLSCDGFCRFLMSDENAPVFLDRLEVYQE-MDHPLSHYFINSSHNTYLTGRQFGGKSSVEIYRQVLLTGCRCVELDCWDGKGEDQEPIITHGK---------------AMCTDVLFKDVIQGIKETAFLTSEYPVILSFENHCT-KHQQYKLARYCEDIFGDLLLKQPLEDFPMEP-GCPLPSPNDLKGKILIKNRRLKPEVEKKQLEDFRKHMEAGEPSVSTNLFEDENEDETNTAELLNEAHPERIHG---------------------------------------CLITEEENRE----------------EEVLLRHRKAEEENVAD------------------------ELAVIQSYTYVAATTNIHPYLSNIINYAQAVKFTGFDEAEEKNIHH----------------------NMSSFNESVGLGYLRTNAI--EFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNFQTPDLAMQLNQGKFEYNGS-------CGFLLKPD---FMRRPDRMFDPFSETPVDGVIAATCSVQVISGQFLSDKK----------IGTYVEVDMYG-------LPTDTIRKEFRTRMV----MNNGLNPVYNAEAFVFRKVILPDLAVLRVAVYD-----DNNKLIGQRILPLDGLQSG--YRHISLRNEYNKPLPLATVFCNIILKTYVP----------------------DGFGAIVDALSDPKKFLSICEKRTDQMRAMGIETS-------------------------------DIADVPSDVWKGNKKRKTNQAGMMMKPQ--------------KDSD-RPRENMPISSKEDSS---VLTPQLTIDDLKQTKTFLKLIKKQQKEVNALKKKHAKAQHALRSSHSAQLDKTVAQHEKEKHTLEKQLHKNTSRKVSESSS-------------------------------------------------------------------------------------------------------------------LEMSRDIEQQMKTAVMNHKSKVKDMASAQASECSEMLRWHSAEEQTVVEQHLLQQCEQLHKLLMLE-QEQQTHQLTLLHERQSKEMRTNQAKTSMESSKAISQDKSIKNKAERERRVRELNSTNTRKFLTERKRLAMKQTK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ECEQLQAAQREQLERLEKHNEELSNSCYAKSQCQ------------------------------------GQNEAVCGDMREDEPLTGQTHMSLQ-----------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13217-1", "uniprot_id": "PIPA_DROME", "id": "P13217-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MTKK---YEFDWII-----------------------------------PVPPELTTGCVFDRWFENEKETKENDFERDALFKVDEYGFFLYWKSEGR------DGDVIELCQVSDIRAGGTPKDPKILDKVTKK-NGTNIPELDKRSLTICSNTDYINITYHHVICPDAATAKSWQKNLRLITHNNRATNVCP-----------RVNLMKHWMRLSYCVEKS-------GKIPVKTLAKTFASG-KTEKLVYTCIKDAGLPDDKNAT-MTKEQFTFDKFYALYHKVCPRNDIEELFTS----------ITKGKQ-DFISLEQFIQFMNDKQRDPRMNEILYPLYEEKRCTEIINDYELDEEKKKNVQMSLDGFKRYLMSDENAPVFLDRLDFYME-MDQPLAHYYINSSHNTYLSGRQIGGKSSVEMYRQTLLAGCRCVELDCWNGKGEDEEPIVTHGH---------------AYCTEILFKDCIQAIADCAFVSSEYPVILSFENHCN-RAQQYKLAKYCDDFFGDLLLKEPLPDHPLDP-GLPLPPPCKLKRKILIKNKRMKPEVEKVELELWLK----GELKTDDDPEEDASAGKPPEAAAAPAPAPEAAAA---------------------------------------AEGAAEGGGG----------------AEAEA-----------------------------------------AAANYSGSTTNVHPWLSSMVNYAQPIKFQGFDKAIEKNIAH----------------------NMSSFAESAGMNYLKQSSI--DFVNYNKRQMSRIYPKGTRADSSNYMPQVFWNAGCQMVSLNFQSSDLPMQLNQGKFEYNGG-------CGYLLKPD---FMRRADKDFDPFADAPVDGVIAAQCSVKVIAGQFLSDKK----------VGTYVEVDMFG-------LPSDTVKKEFRTRLV----ANNGLNPVYNEDPFVFRKVVLPDLAVLRFGVYE-----ESGKILGQRILPLDGLQAG--YRHVSLRTEANFPMSLPMLFVNIELKIYVP----------------------DGFEDFMAMLSDPRGFAGAAKQQNEQMKALGIEE--------------------------------QSGGAARDAGKAKEEEKKEPP--------------------------------------------LVFEPVTLESLRQEKGFQKVGKKQIKELDTLRKKHAKERTSVQKTQNAAIDKLIKGKSKDD------------------------------------------------------------------------------------------------------------------------------------------------------IRNDANIKNSINDQTKQWTDMIARHRKEEWDMLRQHVQDSQDAMKALMLTV-QAAQIKQLEDRHARDIKDLNAKQAKMSADTAKEVQNDKTLKTKNEKDRRLREKRQNNVKRFMEEKKQIGVKQGR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AMEKLKLAHSKQIEEFSTDVQK------LMDMYK------------------------------------IEEEAYKTQGKTEFYA--------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32383-1", "uniprot_id": "PLC1_YEAST", "id": "P32383-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1", "aln": "--------------------------------------------------------MTESAIDDQRFNLTKELQRHSCRDQGKITQKDDALDFISYSSFQSSFNTDQKSANNGSTVRRSIRSIFRRAAELPRVHMGPLTYSHGINELVNKKLR---------------------------KDCDLSTLCRVLQRGIRMIRMTRRR--------RKFYEFKLINNNGQIIWKDGSK---------YLELDSVKDIRIGDTASTYQEEVD-------PKRLRSDSKLWIAIIYKVSNKLKALHVVALNELDFNTFLSCICGLVKLRRELMESILLPD------NSQFARIHWQITVSEKEED-------EKKDTLSFADVKKLCDKFHIYVSTGQLLEFFQLADIN---HNGLLNYFEFEKFIKILKNRKEVNMIWSK-----------FTKPPHSHLSFENFFQFLITEQHEQVDRQTAWS-------------YFIKYREPTQLTMGQDGFTKFLKEQ------PYLVEVKEELYSKPLNHYFIASSHNTYLLGKQIAETPSVEGYIQVLQQGCRCVEIDIWD---GENGPVVCHGF----------------LTSAIPLKTVIRVIKKYAFITSPYPLIISLEINCN-KDNQKLASLIMREVLAEQLYFVGTRTDK-------LPSPRELKHKILLKSKKTSEATRGLSVNEPFPSSFSSS----------------------------------------------------------------------YESANEQELRMK--------------DDSTNSSSATNSSSMQR------------------------------------IKRIGLKKHADIINDVSNISGIHGIKFRNFSLPESK------------------TIAHCFSLNERKVEYMIKDKHLKLSLDKHNRRYLMRVYPHVLRYKSSNFNPIPFWKAGVQMVATNWQTNDIGQQLNLAMFQILDHQPDGSFKSGYVLKPKKLLPVVTKAKMIPLIYEHFENGSDPVTVKIRILSTQLLPRLN--DTSPSRNNTNSFVKVEFHTDDEPTMPISIDKGTRISATEASTKSSQGNGFNPIWDAE--VSITLKDTDLTFIKFMVIS------EETQIASVCLKLNYLRMG--YRHIPLFNMEGEQYIFCTLFIHTQIL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : : : *: * : : : . : *: * : :*:.:** *. . : ***.:*:. * : : : : . ** . :*::: : . :* : : :*.* * .:: :: . * : .: : : : . . : * : ", "identical_positions": 22, "similar_positions": 58, "identity": "1.05%" }, { "cls_id": "homologset.agr.SGD:S000006191", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JI39-1", "uniprot_id": "ABCBA_MOUSE", "id": "Q9JI39-1", "name": "ATP-binding cassette sub-family B member 10, mitochondrial", "aln": "MRAPSARALLLIPRRGPAVRAWAPAVSSRIWLASEWTP----------LVRAWTS---LIHKPGSGLRFPAPLSG-LPGG----------VGQWATSSGARRCWVLAGPRAAHPLFARLQGAAATGVRD------------LGNDSQRRPAATGRSEVWKLLGLVRPERGRLSAAVGFLAVSSVITMSAPFFLGRIIDVIYTNPSEGYGDS--------LTRLCAVLTCVFLCGAAANGIRVYLMQSSGQSIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENLSDGLRAGAQASVGVGMMFFVSPSLATFVLSVVPPISVLAVIYGRYLRKLSKATQDSLAEATQLAEERIGNIRTIRAFGKEMTEVEKYTGRVDQLLQLAQKEALARAGFFGAAGLSGNLIVLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVGLSIGGLSSFYSELMKGLGAGGRLWELLERQPRLPFNEGMVLDEKTFQGALEFRNVHFTYPARPEVSVFQDFSLSIPSGSVTALVGPSGSGKSTVVSLLLRLYDPNSGTVSLDGHDIRQLNPVWLRSKIGTVSQEPVLFSCSVAENIAYGADNLSSVTAQQVERAAEVANAAEFIRSFPQGFDTVVGEKGILLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEHLVQEALDRLMEGR--TVLIIAHRLSTIKNANFVAVLDH-GKICEHGTHEELLLKPNGLYRKLMNKQSFLSYNGAEQFLEPARA--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRK6-1", "uniprot_id": "ABCBA_HUMAN", "id": "Q9NRK6-1", "name": "ATP-binding cassette sub-family B member 10, mitochondrial", "aln": "MRGPPAWPLRLLEPPSPAEPGRLLPVAC-VWAAASRVPGSLSPFTGLRPARLWGAGPALLWGVGAARRWRSGCRGGGPGASRGVLGLARLLGLWARGPGSCRCGAFAGPGAPRLPRARFPGGPAAAAWAGDEAWRRGPAAPPGDKGRLRPAAAGLPEARKLLGLAYPERRRLAAAVGFLTMSSVISMSAPFFLGKIIDVIYTNPTVDYSDN--------LTRLCLGLSAVFLCGAAANAIRVYLMQTSGQRIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENLSDGLRAGAQASVGISMMFFVSPNLATFVLSVVPPVSIIAVIYGRYLRKLTKVTQDSLAQATQLAEERIGNVRTVRAFGKEMTEIEKYASKVDHVMQLARKEAFARAGFFGATGLSGNLIVLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVGISIGGLSSFYSELMKGLGAGGRLWELLEREPKLPFNEGVILNEKSFQGALEFKNVHFAYPARPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYDPASGTISLDGHDIRQLNPVWLRSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEIQRVAEVANAVAFIRNFPQGFNTVVGEKGVLLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRLMDGR--TVLVIAHRLSTIKNANMVAVLDQ-GKITEYGKHEELLSKPNGIYRKLMNKQSFISA--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33311-1", "uniprot_id": "MDL2_YEAST", "id": "P33311-1", "name": "ATP-dependent permease MDL2, mitochondrial", "aln": "MLNGRLPLLRLGICRNMLSRPRLAKLPSIRFRSLVTPS-------------------SSQLIPLSRLCLRSPAVG-----------------------KSLILQSFRCNSSKTVPETSLPSASPISKGS-----------ARSAHAKEQSKTDDYKDIIRLFMLAKRDWKLLLTAILLLTISCSIGMSIPKVIGIVLDTLKTSSGSDFFDLKIPIFSLPLYEFLSFFTVALLIGCAANFGRFILLRILSERVVARLRANVIKKTLHQDAEFFDNHKVGDLISRLGSDAYVVSRSMTQKVSDGVKALICGVVGVGMMCSLSPQLSILLLFFTPPVLFSASVFGKQIRNTSKDLQEATGQLTRVAEEQLSGIKTVQSFVAEGNELSRYNVAIRDIFQVGKTAAFTNAKFFTTTSLLGDLSFLTVLAYGSYLVLQSQLSIGDLTAFMLYTEYTGNAVFGLSTFYSEIMQGAGAASRLFELTDRKPSISPTVGHKYKPD--RGVIEFKDVSFSYPTRPSVQIFKNLNFKIAPGSSVCIVGPSGRGKSTIALLLLRYYNPTTGTITIDNQDISKLNCKSLRRHIGIVQQEPVLMSGTIRDNITYGLTYTP--TKEEIRSVAKQCFCHNFITKFPNTYDTVIGPHGTLLSGGQKQRIAIARALIKKPTILILDEATSALDVESEGAINYTFGQLMKSKSMTIVSIAHRLSTIRRSENVIVLGHDGSVVEMGKFKELYANPTSALSQLLNEKAAPGPSDQQLQIEKVIEKEDLNESKEHDDQKKDDNDDNDNNHDNDSNNQSPETKDNNSDDIEKSVEHLLKDAAKEANPIKITPQP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 222, "similar_positions": 260, "identity": "26.75%" }, { "cls_id": "homologset.agr.SGD:S000006192", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29418-1", "uniprot_id": "ATP5E_RAT", "id": "P29418-1", "name": "ATP synthase F(1) complex subunit epsilon, mitochondrial", "aln": "MVAYWRQAGLSYIRFSQICAKAVRDALKTEFK-ANAEKTSGTSIKTVKIKKE--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0R601-1", "uniprot_id": "M0R601_RAT", "id": "M0R601-1", "name": "ATP synthase F(1) complex subunit epsilon, mitochondrial", "aln": "MVAYWQQAGLSYIRFSQICAKAVRDALKTEFK-ANAEKTSGSSIKTVKVKKPD-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56382-1", "uniprot_id": "ATP5E_MOUSE", "id": "P56382-1", "name": "ATP synthase F(1) complex subunit epsilon, mitochondrial", "aln": "MVAYWRQAGLSYIRFSQICAKAVRDALKTEFK-ANAEKTSGSSIKIVKVSKKE-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56381-1", "uniprot_id": "ATP5E_HUMAN", "id": "P56381-1", "name": "ATP synthase F(1) complex subunit epsilon, mitochondrial", "aln": "MVAYWRQAGLSYIRYSQICAKAVRDALKTEFK-ANAEKTSGSNVKIVKVKKE--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5VTU8-1", "uniprot_id": "AT5EL_HUMAN", "id": "Q5VTU8-1", "name": "ATP synthase subunit epsilon-like protein, mitochondrial", "aln": "MVAYWRQAGLSYIRYSQICAKVVRDALKTEFK-ANAKKTSGNSVKIVKVKKE--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXN2-1", "uniprot_id": "SUN_DROME", "id": "Q9VXN2-1", "name": "Protein stunted", "aln": "MTA-WRAAGITYIQYSNIAARILRESLKTGLR-ADAAKRDASHVKFTPWANGKPAQR---QTQSES", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VH24-1", "uniprot_id": "Q9VH24_DROME", "id": "Q9VH24-1", "name": "", "aln": "MKA-WRDLGITYIQYSNIAARVVREALRIELR-ADAAKRNISHVKFTPWVNGKPVPRKKVERESES", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21306-1", "uniprot_id": "ATP5E_YEAST", "id": "P21306-1", "name": "ATP synthase subunit epsilon, mitochondrial", "aln": "-MSAWRKAGISYAAYLNVAAQAIRSSLKTELQTASVLNRSQTDAFYTQYKNGTAASEPTPITK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: *::* : ::.*: :*.:*: :: *.. : . . . : ", "identical_positions": 7, "similar_positions": 22, "identity": "10.61%" }, { "cls_id": "homologset.agr.SGD:S000006194", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91WS4-1", "uniprot_id": "BHMT2_MOUSE", "id": "Q91WS4-1", "name": "S-methylmethionine--homocysteine S-methyltransferase BHMT2", "aln": "MAPAGSTRAKKGILERLDSGEVVVGDSGFLFTLEKRGFVKAG------------LWTPEAVVEHPSAVRQLHTEFLRAGADVLQTFTFSATEDNMASK---------WEAVNAAACDLAQEVAGGGGALVAGGICQTSLYKYHKDETRIKNIFRLQLEVFARKNVDFLIAEYFEHVEEAVWAVEVLREVGAPVAVTMCIGPEGDMHDVTPGECAVKLARAGADIIGVNCRFGPWTSLQTMKLMKEGLRDASLQAHLMVQCLGFHTPDCGKGGFVDLPEYPFGLEPRVATRWDIQKYAREAYNLGIRYIGGCCGFEPYHIRAIA-EELAPERGFLPPASEKHG-SWGSGLNMHTKPWIRARARREYWENLLPASGRPFCPSLSKPDA----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68FT5-1", "uniprot_id": "BHMT2_RAT", "id": "Q68FT5-1", "name": "S-methylmethionine--homocysteine S-methyltransferase BHMT2", "aln": "MAPAGGPRVKKVILERLDSGEVVVGDGGFLFTLEKRGFVKAG------------LWTPEAVVEYPSAVRQLHTEFLRAGADVLQTFTFSAAEDRMESK---------WEAVNAAACDLAQEVADGGAALVAGGICQTSLYKYHKDETRIKNIFRLQLGVFARKNVDFLIAEYFEHVEEAVWAVEVLREVGAPVAVTMCIGPEGDMHGVTPGECAVRLSRAGANIIGVNCRFGPWTSLQTMKLMKEGLRDAGLQAHLMVQCLGFHTPDCGKGGFVDLPEYPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIA-EELAPERGFLPPASEKHG-IWGSGLDMHTKPWIRARARREYWETLLPASGRPFCPSLSKPDA----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H2M3-1", "uniprot_id": "BHMT2_HUMAN", "id": "Q9H2M3-1", "name": "S-methylmethionine--homocysteine S-methyltransferase BHMT2", "aln": "MAPAGRPGAKKGILERLESGEVVIGDGSFLITLEKRGYVKAG------------LWTPEAVIEHPDAVRQLHMEFLRAGSNVMQTFTFSASEDNMESK---------WEDVNAAACDLAREVAGKGDALVAGGICQTSIYKYQKDEARIKKLFRQQLEVFAWKNVDFLIAEYFEHVEEAVWAVEVLKESDRPVAVTMCIGPEGDMHDITPGECAVRLVKAGASIVGVNCRFGPDTSLKTMELMKEGLEWAGLKAHLMVQPLGFHAPDCGKEGFVDLPEYPFGLESRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIA-EELAPERGFLPPASEKHG-SWGSGLDMHTKPWIRARARREYWENLLPASGRPFCPSLSKPDF----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q93088-1", "uniprot_id": "BHMT1_HUMAN", "id": "Q93088-1", "name": "Betaine--homocysteine S-methyltransferase 1", "aln": "MPPVGGKKAKKGILERLNAGEIVIGDGGFVFALEKRGYVKAG------------PWTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYASEDKLENRGNYVLEKISGQEVNEAACDIARQVADEGDALVAGGVSQTPSYLSCKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPVAATMCIGPEGDLHGVPPGECAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAARLKAHLMSQPLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIA-EELAPERGFLPPASEKHG-SWGSGLDMHTKPWVRARARKEYWENLRIASGRPYNPSMSKPDGWGVTKGTAELMQQKEATTEQQLKELFEKQKFKSQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJ32-1", "uniprot_id": "Q9VJ32_DROME", "id": "Q9VJ32-1", "name": "Hcy-binding domain-containing protein", "aln": "--------MGLTR--------VLVKDGGFGTQMTVHVGDSVDGDP---------LWSARFNATNPAAIISTHLDFLQNGADIILTNTYQSSVDGYMEY---------LELDEEQSIELIKNTVR-----LAHIAKERYLTECYQAQLSVQEGYPLIIASIGPFGAHLHDGSEYTGSYADFVPAKEITDWHR-VRIEACLEAGVDALAIETIPCQMEAEALVEMLCDDYPDVKFWVAFQCKDENTLAHGETFADAANAIWDLLAERNAQDKCLAIGVNCVHPKFVTPLFKSLNGDREVGEQIPLVVYPNSGEVYDVVNG-WQGR-EHCVPLANYVPEWAQLGAKVIGGCCRTYARDIRHIGEAIRDWNKLKKLS-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJ31-1", "uniprot_id": "BHMT_DROME", "id": "Q9VJ31-1", "name": "Betaine-homocysteine S-methyltransferase", "aln": "--------MEVNQKWNWDTKPILVKCGGFSSQLAKNVTEKVDGDP---------LWGSRFDATNPEAVIQTHLDFLRNGADIILTNTYQSSVEGFVKY---------LGVTRERGVELIQKSVQ-----LAKQAKEQYLSEIGS---EAESALPLIMGSIGPYGAYLHDGSEYTGNYADKMSKEELRAWHK-TRIEICLAAGVDGLALETLPCLMEAEAVTELVLDNFPDAKFWVSLQCMDEKHMASGENFAEAALSLWRLVQSRKAENRLLGIGLNCVNPLFVTPLLSSLT-KVAGSDRIPLVVYSNRGEIYDVEQGDWTG---TGEEVVKFVPEWIQLGVRIVGGCCRVYPTDVLAIRKYVDGLN-IKP-------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08985-1", "uniprot_id": "SAM4_YEAST", "id": "Q08985-1", "name": "Homocysteine S-methyltransferase 2", "aln": "-----MARLPLKQFLADNPKKVLVLDGGQGTELENRGIKVANPVWSTIPFISESFWSDESSANR-KIVKEMFNDFLNAGAEILMTTTYQTSYKSVSEN---------------TPIRTLSEYNN-------------LLNRIVDFSRNCIGEDKYLIGCIGPWGAHICR--EFTGDYGAEPENIDFYQYFKPQLENFNKNDKLDLIGFETIPNIHELKAILSWDESILSRP-FYIGLSVHEHGVLRDGTTMEEIAQVIKDLGDKINPN--FSFLGINCVSFNQSPDILESLHQALPN---MALLAYPNSGEVYDTEKKIWLPNSDKLNSWDTVVKQYISSGARIIGGCCRTSPKDIQEISAAVKKYT-----------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: .. : . .. * . : . . :**. *:::: * *: :: . . : . : : .. : : : * . . . . .:. . . * :.: . : * * : . *. . ", "identical_positions": 11, "similar_positions": 51, "identity": "2.62%" }, { "cls_id": "homologset.agr.SGD:S000006195", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TBB6-1", "uniprot_id": "S7A14_HUMAN", "id": "Q8TBB6-1", "name": "Solute carrier family 7 member 14", "aln": "--------MSGFFTSLDPRRVQW----GAAWYAMHSRILRTKPVESMLEGTGTTTAHGTK------------LAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAVWVFIMIAGLFFING----------KYWAEGQ--FLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVKFLSEEHTKKKEGILADCEKEACSPVSEGDEFSGPATNTCGAKNLPSLGD-------NEMLIGKSDKSTYNVNHPN--YGTVDMTTGIEADESENIYLIKLKKLIGPHYYTMRIRLGLPGKMD--RPTAATGHTVTICVLLLFILMFIFCSFIIFGSDYISEQSWWAILLVVLMVLLISTLVFVILQQPENPKKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVWCFVGLLIYFGYGIWNSTLEIS---------------------------------AREEALHQSTYQRYDVDDPFS---VEEGFSYATEGESQEDWGGPTED---KGFYYQQMSDAKANGRTSSKAKSKSKHKQNSEALIANDELDYSPE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZSU3-1", "uniprot_id": "D3ZSU3_RAT", "id": "D3ZSU3-1", "name": "", "aln": "--------MSGFLSSLDPRRVQW----GAAWYAMHSRILRTKPVESMLEGTGATSAHGTK------------LAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMVDTVGTLNGLGKGEESYPDLLALVIAVIVTIIVALGVKNSVGFNNVLNVLNLAVWVFIMIAGLFFVNG----------KYWAEGQ--FLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSMILTLMVPYYAIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLSLLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVKFLSEEHTKKKEGILADCEKETCSPVSEGEEFSSPATNTCGAKNLPSLGD-------NEMLIGKSDKSAYNVNHPN--YGTVDMTTGIEADESENIYLIKLKKLIGPRYYTMRIRLGLPGKMD--RPTAATGHTVTICVLLLFILMFIFCSFVIFGSEYISGQSWWAILLVVLMLLLITVLVFVILQQPENPKKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVWCFVGMLIYFGYGIWNSTLEIS---------------------------------AREQALHQSTYQRYDVDDPFS---VEEGFSYATEGESQEDWGGPAED---KGFYYQQMSDAKANSRTSSKAKSKSKHKQNSEALIENDELDCSPE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VWD3-1", "uniprot_id": "Q9VWD3_DROME", "id": "Q9VWD3-1", "name": "Cationic amino acid transporter C-terminal domain-containing protein", "aln": "------MKPSDLLLVLEKVKFRVPLPPGVSSTTLLPKLIRTKDVKQLQDGN--AQPQKPK------------LTKCLNTLDLTSLGIGSCCGTGMYLVAGMVAQKIAGPGVIISFIIAAIASIFSGACYAEFGVRVPHTSGSAYMYSYVAVGEFVAFIIGWNMILEYLIGTSACACALSSSFDSLTGNAIARTISESIGTIFGKP------PDFIAFGITLLMTCVLAMGASKSVIFNHSLNAVNLATWVFVMAAGLFYVDT----------KTWSEHQG-FLPYGWSGVFSGAATCFYAFIGFDIIATTGEEAHNPQKSIPKAIVGSLVVVLIAYVSVSLVLTLVVPYDHINTGAALVQMWSYVNAPKCRAVVAIGATAGLSVAMFGSMFPMPRVIYAMAQDGLIFRQLSQLWHRTNVPGLATIGSGLAAALVALTVRLEILVEMMSIGTLLAYTLVSTCVLVLRYQPHS--TSLVELLPAQLRTPVAHGTASDSRSHVTPA-EVLEVPGKLTIKRVTRGMSDSDDSFIDDSPEGFLGGRDDQFLVSDRSENKFYGSVHGAPTGPTGQATAFDAMGLNFVTRKIHDYAYLCPGFFPWINPGQATAESGMYVTKLVGIMFGLIFFLDLFAAIG---WSGG--LAAFIYFILFIGIFVILLIISRQPQNRYALAFLTPGLPFIPAIAITVNIYLIFKLSILTLVRFTVWMSLGFIMYFYYGITHSSLEQASDDLELHVDYSKNVEEKAVWDQQSYNQTHEPVWASKEVKQPSTEQRYNYGKTTSSSSSAQGSSRSGQGSAPEKPAGRSTAGLNRPVPPPPIAGQAKGSGSGSGPPMERQYTGQFSMFVDEGQFPTWDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B5DFJ0-1", "uniprot_id": "B5DFJ0_RAT", "id": "B5DFJ0-1", "name": "", "aln": "-----------MARGLPS---------TARLARFCQKLNRLKPLE--------ESSTETS------------LRRCLSTLDLTLLGVGGMVGSGLYVLTGTVAKDMAGPAVLLSFLVAAVASLLAALCYAEFGARVPRTG-SAYLFTYVSMGEIWAFLIGWNVLLEYLIGGAAVARAWSGYLDAIFNHSIRNFTESHMGVWQMPFLA--HYPDFLAAGILLVASAFVSCGARVSSWLNHTFSAISLIVILFIIVLGFILARP----------HNWSAEEGGFAPFGFSGILAGTATCFYAFVGFDVIAASSEEAKNPRWAVPMAIAISLGLAAGAYILVSTVLTLMVPWHSLDPDSALADAFYRRGYGWAGFIVAVGSICAMNTVLLSNLFSLPRIVYAMAADGLFFQVFARVHPRTQVPVVGILVFGVLMALLALLMDLEALVQFLSIGTLLAYTFVATSIIVLRFQKAS-----------------------------PPSSPCPASPGPTVKKY---------------------------------------------------DSFSDHIQLVDAVQASMSEPGQLRPALKPFLG-FLDGLSPGTAVTWALGILIASAISLACVLVFGNSALHLPRWGYVLLLVVSGAVFLSSLLVLGAHQQQKKQDTFQIPLVPLTPALSILLNLCLMLKLSYLTWLRFIFWLLVGLVVYFGYGIWHSKENQR----------------------------------EPLELTTAHYVVFPSGS---------------------------------------LEETVQAVQPDSQTPVQGPGCTE---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLQ7-1", "uniprot_id": "CTR4_MOUSE", "id": "Q8BLQ7-1", "name": "Cationic amino acid transporter 4", "aln": "-----------MARGLPS---------TACLARFCQKLNRLKPLE--------ESSMETS------------LRRCLSTLDLTLLGVGGMVGSGLYVLTGTVAKDMAGPAVLLSFLVAAVASLLAALCYAEFGARVPRTG-SAYLFTYVSMGEIWAFLIGWNVLLEYLIGGAAVARAWSGYLDAIFNHSIRNFTESHLGVWQVPFLA--HYPDFLAAGILLVASAFVSCGARVSSWLNHTFSAISLIVILFIIVLGFILARP----------HNWSAEEGGFAPFGFSGILAGTATCFYAFVGFDVIAASSEEAKNPRWAVPMAIAISLSLAAGAYILVSTVLTLMVPWHSLDPDSALADAFYRRGYSWAGFIVAVGSICAMNTVLLSNLFSLPRIVYAMAADGLFFQVFARVHPRTQVPVVGILVFGVLMALLALLLDLEALVQFLSIGTLLAYTFVATSIIVLRFQKAS-----------------------------PPSSPCLASPGPTAKKY---------------------------------------------------DSFSDHIQLVGAEQTSMSEPGQLRPALKPFLG-FLDGCSPGTAVAWALGILVASAISLACVLVFGNSDLHLPQWGYVLLLVISGAVFLSSLLVLGAHQQQKKQDTFQIPLVPLTPALSILLNTCLMLKLSYLTWLRFIFWLLVGLVVYFGYGIWHSKENQR----------------------------------EPLELTTAHYVVFPSGS---------------------------------------LEETVQAVQPSSQSPVRESGCTE---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43246-1", "uniprot_id": "CTR4_HUMAN", "id": "O43246-1", "name": "Cationic amino acid transporter 4", "aln": "-----------MARGLPT---------IASLARLCQKLNRLKPLE--------DSTMETS------------LRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAVLLSFGVAAVASLLAALCYAEFGARVPRTG-SAYLFTYVSMGELWAFLIGWNVLLEYIIGGAAVARAWSGYLDSMFSHSIRNFTETHVGSWQVPLLG--HYPDFLAAGIILLASAFVSCGARVSSWLNHTFSAISLLVILFIVILGFILAQP----------HNWSADEGGFAPFGFSGVMAGTASCFYAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKSS-----------------------------PPSSPGPASPGPLTKQQ---------------------------------------------------SSFSDHLQLVGTVHASVPEPGELKPALRPYLG-FLDGYSPGAVVTWALGVMLASAITIGCVLVFGNSTLHLPHWGYILLLLLTSVMFLLSLLVLGAHQQQYREDLFQIPMVPLIPALSIVLNICLMLKLSYLTWVRFSIWLLMGLAVYFGYGIRHSKENQR----------------------------------ELPGLNSTHYVVFPRGS---------------------------------------LEETVQAMQPPSQAPAQDPGHME---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08986-1", "uniprot_id": "SAM3_YEAST", "id": "Q08986-1", "name": "S-adenosylmethionine permease SAM3", "aln": "MDILKRGNESDKFTKIETESTTIPNDSDRSGSLIRRMKDSFKQSNLHVIPEDLENSEQTEQEKIQWKLASQPYQKVLSQRHLTMIAIGGTLGTGLFIGLGYSLASGP-AALLIGFLLVGTSMFCVVQSAAELSCQFPVSG-SYATHVSRFIDESVGFTVATNYALAWLISFPSELIGCALTISYWN-QTVN--------------------PAVWVAIFYVFIMVLNLFGVRGFAETEFALSIIKVIAIFIFIIIGIVLIAGGGPNSTGYIGAKYWHDPGAFAKPVFKNLCNTFVSAAFSFGGSELVLLTSTESKN-ISAISRAAKGTFWRIAIFYITTVVIIGCLVPYN----DPRLLSGSNSEDVSASPFVIALSNTGSMGAKVSNFMNVVILVAVVSVCNSCVYASSRLIQALGASGQLPSVCS----------YMDRKGRPLVGIGISGAFGLLGFLVASKKE-----------------------------------------------------------------------------------------------------DEVFTWLFALCSISSFFTWFCICMSQIRFRMALKAQGRSNDEIAYKSILGVYG----------------------GILGCVLNALLIAGEIYVSAAPVGSPSS---AEAFFEYCLSIPIMIVVYFAHRFYRRDWKHFYIKRSE-IDLDTGCSVENLELFKA-------------------------------------------------------------------------------------------QKEAEEQLIASKPFYYKIYRFWC--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * : . .. : *. .* :.:*. *:*::: * . . ..:::.* :.. : : . **:. :.* : * . :.* .* :. * * ::*. .: . : :. ::: * . . : :. . *. : :. :.: . .:.: *:. : * :..: .:. ::* * ::: :. *::* ::. * :: *: . :: :**: . * . . . ::* . .: . : . : : : . . :. .: : : . ::.:* *: ::. : : . : : : . . : : : .: : : : . . . ::.: : : :: :* . : : .: : * . ", "identical_positions": 35, "similar_positions": 169, "identity": "4.08%" }, { "cls_id": "homologset.agr.SGD:S000006202", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15429-1", "uniprot_id": "ENOB_RAT", "id": "P15429-1", "name": "Beta-enolase", "aln": "-------------------------------------------------------------------MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPD--LVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSP-DDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKAVFAGRKFRNPKAK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21550-1", "uniprot_id": "ENOB_MOUSE", "id": "P21550-1", "name": "Beta-enolase", "aln": "-------------------------------------------------------------------MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKARYLGKGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPD--LVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSP-DDPARHISGEKLGELYKNFIQNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKAVFAGRKFRNPKAK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13929-1", "uniprot_id": "ENOB_HUMAN", "id": "P13929-1", "name": "Beta-enolase", "aln": "-------------------------------------------------------------------MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGKGVLKAVENINNTLGPALLQKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPD--LILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSP-DDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKAIFAGRKFRNPKAK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17183-1", "uniprot_id": "ENOG_MOUSE", "id": "P17183-1", "name": "Gamma-enolase", "aln": "-------------------------------------------------------------------MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSRIAPALISSGISVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERDLPLYRHIAQLAGNSD--LILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKMVIGMDVAASEFYRDGKYDLDFKSP-ADPSRYITGDQLGALYQDFVRNYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09104-1", "uniprot_id": "ENOG_HUMAN", "id": "P09104-1", "name": "Gamma-enolase", "aln": "-------------------------------------------------------------------MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAGNSD--LILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSP-TDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04764-1", "uniprot_id": "ENOA_RAT", "id": "P04764-1", "name": "Alpha-enolase", "aln": "-------------------------------------------------------------------MSILKIHAREIFDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDNDKTRFMGKGVSKAVEHINKTIAPALVSKKLNVVEQEKIDQLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNPE--VILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKSAIAKAGYTDQVVIGMDVAASEFYRAGKYDLDFKSP-DDASRYITPDQLADLYKSFIKDYPVVSIEDPFDQDDWDAWQKFTATAGIQVVGDDLTVTNPKRIAKAAGEKSCNCLLLKVNQIGSVTESLQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGSKAKFAGRSFRNPLAK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5YC61-1", "uniprot_id": "A0A8I5YC61_RAT", "id": "A0A8I5YC61-1", "name": "phosphopyruvate hydratase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MLFPVGESKKLNVVEQEKIDQLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNPE--VILPVPAFNVINGGSHAGHKLAMQEFMILPVGASSFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNNLENKDALELLKSAIAKAGSTDQVVIGMDVAASEFYRAGKYDLDFKSP-DDASWYITPDQLADLYKSFIKDYPVVSIEDPFDQDDWD------------VVGDDLTVTSPKRIAKAAGEKSCNCLLLKVNQIGSVTESLQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGSKAKFAGRSFRNPLAK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06733-1", "uniprot_id": "ENOA_HUMAN", "id": "P06733-1", "name": "Alpha-enolase", "aln": "-------------------------------------------------------------------MSILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKGVSKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNSE--VILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYTDKVVIGMDVAASEFFRSGKYDLDFKSP-DDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDDWGAWQKFTASAGIQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACKLAQANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKAKFAGRNFRNPLAK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q1X2-1", "uniprot_id": "A0A2R8Q1X2_DANRE", "id": "A0A2R8Q1X2-1", "name": "phosphopyruvate hydratase", "aln": "-------------------------------------------------------------------MSILKIHAREIFDSRGNPTVEVDLYTKKGLFRAAVPSGASTGIYEALELRDNDKTRYLGKGVKRAVKYVNEFLAPALCNQNVSVLEQEKIDKLMLDMDGTDNKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPE--VILPVPAFNVINGGSHAGNKLAMQEFMILPVGASNFKEAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKNAISKAGYTDKIVIGMDVAASEFYKGGKYDLDFKSP-DDPSRYISPDKLADLYKSFVKDYPVVSIEDPFDQDDWEAWTNFTATTNIQVVGDDLTVTNPKRIAKAVSDKACNCLLLKVNQIGSVTESLQACKMAQTNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGDKARFAGKNFRKPI--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15007-1", "uniprot_id": "ENO_DROME", "id": "P15007-1", "name": "Enolase", "aln": "MSWTASVFLRTSTTSMKFLRLRWPLPRIPQNKSANVAPRFRSKSAVSQLSSGFKFVQIRKSTCDSNEMTIKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDNDKANYHGKSVLKAVGHVNDTLGPELIKANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAKAGAAKKGVPLYKHIADLAGNKE--IILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAMKMGSEVYHHLKNVIKAKFGLDATAVGDEGGFAPNIQSNKEALNLISDAIAKAGYTGKIEIGMDVAASEFYKDGQYDLDFKNEKSDKSQWLPADKLANLYQEFIKDFPIVSIEDPFDQDHWEAWSNLTGCTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGTVTESIAAHLLAKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEIGAGVKFAGKSFRKPQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX11-1", "uniprot_id": "ERR2_YEAST", "id": "P0CX11-1", "name": "Enolase-related protein 2", "aln": "-------------------------------------------------------------------MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSELCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVEAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . : * :* :*::*:.:***.***::**********.*.:*.*.:: :.**::**:**. : .::*** ***:***:*** .****** * *.** .* :**::*:**** ** : * ::* .* ******.**: .:.*::: ** .* :: :*:* *.* *:: *:***:**. * : :. :*. *:.:::.:*::*:***: :*.* ::.**** *. .** * .*..* ****:****::**:: * * ***.*:*********.**.****** ****:** .*********:::**** :* :**: *:. ", "identical_positions": 164, "similar_positions": 107, "identity": "32.54%" }, { "cls_id": "homologset.agr.SGD:S000006205", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VHF5-1", "uniprot_id": "CISY_RAT", "id": "Q8VHF5-1", "name": "Citrate synthase, mitochondrial", "aln": "MALLTA---AARLLGAKNSSCLVLAARHASASSTNLKDILSNLIPKEQARVKTFRQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGYSIPECQKLLP-KAKGGEEPLPEGLFWLLVTGQMPTEEQVSWLSQEWAKR-AALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGIN-RTKYWELIYEDCMDLIAKLPCVAAKIYRNLYREGSSIGAIDSKLDWSHNFTNMLCYT---------------EPQFTELMRLYLTIHSDHDGGNVSAHTSHLVGSALSDTYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYSCQREFALKH---LPKDPMFKLVAQLYKIVPNILLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLMKFVDSKSG---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CZU6-1", "uniprot_id": "CISY_MOUSE", "id": "Q9CZU6-1", "name": "Citrate synthase, mitochondrial", "aln": "MALLTA---ATRLLGAKNSSCLVLAARHASASSTNLKDVLSNLIPKEQARIKTFKQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGYSIPECQKMLP-KAKGGEEPLPEGLFWLLVTGQMPTEEQVSWLSREWAKR-AALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGMN-RAKYWELIYEDCMDLIAKLPCVAAKIYRNLYREGSSIGAIDSRLDWSHNFTNMLGYT---------------DPQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYSCQREFALKH---LPKDPMFKLVAQLYKIVPNILLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLMKFVDSK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75390-1", "uniprot_id": "CISY_HUMAN", "id": "O75390-1", "name": "Citrate synthase, mitochondrial", "aln": "MALLTA---AARLLGTKNASCLVLAARHASASSTNLKDILADLIPKEQARIKTFRQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLP-KAKGGEEPLPEGLFWLLVTGHIPTEEQVSWLSKEWAKR-AALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSESNFARAYAQGIS-RTKYWELIYEDSMDLIAKLPCVAAKIYRNLYREGSGIGAIDSNLDWSHNFTNMLGYT---------------DHQFTELTRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKH---LPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTEGLMKFVDSKSG---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVY5-1", "uniprot_id": "CISY_DANRE", "id": "Q7ZVY5-1", "name": "Citrate synthase, mitochondrial", "aln": "MSFLSISRLAPRLLSSKNAACVVVAARNASAS-TNLKDVLSDLVPKEQSRIKNFKQQYGKTSIGQITVDMVYGGMRGVKGLVYETSVLDPDEGIRFRGYSIPECQQLLP-KAPGGEEPLPEGLFWLLVTGQVPTEEQVSWLSKEWAKR-AALPSHVVTMLDNFPTNLHPMSQFSAAITALNSESSFARAYSEGVN-KAKYWEFVYEDSMDLIAKLPCVAAKIYRNLYREGSSIGAIDSNLDWSHNFTNMLGYT---------------EPQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFSAAMNGLAGPLHGLANQEVLVWLTALQKELGGEVSDEKMRDYIWNTLKSGRVVPGYGHAVLRKTDPRYTCQREFALKH---LPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLVWSRALGFPLERPKSMSTDGLMALVGAKSG---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43635-1", "uniprot_id": "CISY3_YEAST", "id": "P43635-1", "name": "Citrate synthase 3, mitochondrial", "aln": "MVQR-------LLPGAHICRRSFNSSAIIKSSALTLKEALENVIPKKRDAVKKLKACYGSTFVGPITISSVLGGMRGNQSMFWQGTSLDPEHGIKFQGLTIEECQNRLPNTGIDGDNFLPESMLWLLMTGGVPTFQQAASFRKELAIRGRKLPHYTEKVLSSLPKDMHPMTQLAIGLASMNKGSLFATNYQKGLIGKMEFWKDTLEDSLNLIASLPLLTGRIYSNITNEGHPLGQYSEEVDWCTNICSLLGMTNGTNSSNTCNLTSQQSLDFINLMRLYTGIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMGLAGPLHGLAAQEVVRFLIEMNSNISSIAREQEIKDYLWKILNSNRVIPGYGHAVLRKPDPRFTAMLEFAQKRPIEFENDKNVLLMQKLAEIAPKVLLEHGKSKNPFPNVDSASGILFYHYGIRELLFFTVIFGCSRAMGPLTQLVWDRILGLPIERPKSLNLEGLEALTKASNVNKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * .:: . . :: .:* .**: * :::**:: :*.:: :*.* :* **:. : ***** :.:.:: : ***:.**:*:* :* ***: ** .. .*:: ***.::***:** :** :*.: : :* * * ** :. .:*..:*.::***:*:: .::::*. * ** * :*: : ::*: **.::***.** ::.:** *: .** :* ...:**. *: .:* * . :* :* *** ** **:********:*********.***:::.: ********** ***: :* ::.::. . :::::**:*: *:*.**:**********.***::. *** *: : :* . *: :* :*.*::***:**:***:****: **:*: :**: *: ::**:** ***:* *:**:*.* **:*:*****:. :** :. :. ", "identical_positions": 193, "similar_positions": 167, "identity": "39.15%" }, { "cls_id": "homologset.agr.SGD:S000006206", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWM1-1", "uniprot_id": "D3ZWM1_RAT", "id": "D3ZWM1-1", "name": "Cis-aconitate decarboxylase", "aln": "-MMLKSVTES-FASMIHGLRVGHLTDGVIQRSKR------------------------------MILDSLGVGFLGTGTEVFHNVTQYSKIYSSNTSSTVWGRPDFRLPPTYAAFVNGVAIHSMDFDDTWHPAT--HPS---GAVLPVLTALSEALPQTPKFSGLDLLLAFSVGIEVQGRLLH-FSKEAKDIPKRFHPPSVVGTLGSAAATSKFLGLSLTKCREALAIAVSHAGAP----IANAATQTKPLHIGNAAKHGMEATFLAMLGLQGNKQILDLGSGFGAFYANYS--PKDLPSLDSHIWLLDQQDVAFKSFPAHLATHWVADAAAAVRKHLVTSERALLPADHIERIVLRIPDVQYVNRPFPDSEHEAR-HSFQYVACATLLDGSVTVPSFYSQKVNRPQVKELLKKVELEHPPDNLPSFN-----TLYCEISITLKDGTTFTERSDTFYGHWRKPLSQEDLHKKFRANASKILGEDTVESLITVVEKLEDLEDCAMLTRLLKGPSVQEEASKLSSIFSFHHTSLPKFTNI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54987-1", "uniprot_id": "IRG1_MOUSE", "id": "P54987-1", "name": "Cis-aconitate decarboxylase", "aln": "-MMLKSVTES-FAGMIHGLKVNHLTDGIIRRSKR------------------------------MILDSLGVGFLGTGTEVFHKVTQYSKIYSSNTSSTVWGRPDFRLPPTYAAFVNGVAVHSMDFDDTWHPAT--HPS---GAVLPVLTALSEALPQIPKFSGLDLLLAFNVGIEVQGRLMH-FSKEAKDIPKRFHPPSVVGTLGSAAAASKFLGLSLTKCREALAIAVSHAGAP----IANAATQTKPLHIGNAAKHGMEATFLAMLGLQGNKQILDLGSGFGAFYANYS--PEDLPSLDSHIWLLDQQDVAFKSFPAHLATHWVADAAAAVRKHLVTPERALFPADHIERIVLRIPDVQYVNRPFPDSEHEAR-HSFQYVACASLLDGSITVPSFHSQQVNRPQVRELLKKVKLEHPPDNPPSFD-----TLYCEISITLKDGTTFTERSDTFYGHWRKPLSQEDLRNKFRANASKMLCRDTVESLITVVEKLEDLEDCSVLTRLLKGPSVQDEASKLSSMSSFDHTTLPRFTNI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NK06-1", "uniprot_id": "IRG1_HUMAN", "id": "A6NK06-1", "name": "Cis-aconitate decarboxylase", "aln": "-MMLKSITES-FATAIHGLKVGHLTDRVIQRSKR------------------------------MILDTLGAGFLGTTTEVFHIASQYSKIYSSNISSTVWGQPDIRLPPTYAAFVNGVAIHSMDFDDTWHPAT--HPS---GAVLPVLTALAEALPRSPKFSGLDLLLAFNVGIEVQGRLLH-FAKEANDMPKRFHPPSVVGTLGSAAAASKFLGLSSTKCREALAIAVSHAGAP----MANAATQTKPLHIGNAAKHGIEAAFLAMLGLQGNKQVLDLEAGFGAFYANYS--PKVLPSIASYSWLLDQQDVAFKRFPAHLSTHWVADAAASVRKHLVA-ERALLPTDYIKRIVLRIPNVQYVNRPFPVSEHEAR-HSFQYVACAMLLDGGITVPSFHECQINRPQVRELLSKVELEYPPDNLPSFN-----ILYCEISVTLKDGATFTDRSDTFYGHWRKPLSQEDLEEKFRANASKMLSWDTVESLIKIVKNLEDLEDCSVLTTLLKGPSPPEVASNSPACN----NSITNLS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12428-1", "uniprot_id": "PRPD_YEAST", "id": "Q12428-1", "name": "Probable 2-methylcitrate dehydratase", "aln": "MFLAKNLKNNKIKVCLPKKKFAALSTASIQTNERPNPDKVLKDIAKYVHETPLKSSLALDTARLCFLDTLGCGLAALKFKQAQNIIKPIVPGTIVPSGTKILGTSYVMDPVKGAFAIGTLIRWLDYNDCWLAAEWGHPSDNLGGILAVADHLSRLNKATHGKNGKQFLVKDVLEAMIKAHEIQGIIALENSFNKVGLDHVVLVKVATAGVVSKMLGLSQEQTIEALSQAFVDGQSLRTYRHAPNTGSRKSWAAGDAVSRAVNLAYLVKNANVGTIPSVLTARTWGFYDVLFKGKPFSFQQRSKYDSYVMENVLFKISFPAEFHAQTAVEAAVKAYRILAKQGKTFKDIKSIR-IRTQEAAMRIIDKSGPLYNYADRDHCIQYMIAVPLITGNLTATDYSDEVARNPEIDNLRSKMYCIEDTHLTQNYHDPDKRSIGNALLIELNDGTQLDEIFVEY------PVGHKFRREEGIPLLMNKFQRHLREHFVESPDKVDLIMKVSSKTNFLNMQIDKYMDLFTEG---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: *.:.:. : : :. *: *: .:* :**:** *: . : : : : *.* .. : *. .**. *. :: :*::* * .* *** *.:*.* *:. .* ::*: : ::.: :: : :.: * *: .:.:*...**:**** : ***: *. .. : * : . *. *:*..:.:: ::*. . *. : :* : . :. * : . .: : :: : ***.: :: ..:**. . : *. ::: . *. * : . :: :::. * :: * *.:**: .. *: *.:*...: . ..*:: :* .*: .. .:. : : : *:**: : : : *:.:: .:: . : : . * :: .::: : . : * :*: . ", "identical_positions": 75, "similar_positions": 183, "identity": "13.94%" }, { "cls_id": "homologset.agr.SGD:S000006207", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R154-1", "uniprot_id": "S26A4_RAT", "id": "Q9R154-1", "name": "Pendrin", "aln": "-----------------MAARDRRSEPPQLAEYSCSYAVSRPVYS------------------ELAFQQQRERRLPERRTLRDSLA-RSCSCSRKRAFGALKALLPILDWLPKYRVKEWLLSDIISGVSTGLVGTLQGMAYAL-LAAVPVQYGLYSAFFPILTYFVFGTSRHISVGPFPVVSLMVGSVVLSMAPDDHFLVPSGNGSTLNTTTLDT--------------GTRDAARVLLASTLTLLVGIIQLVFGGLQIGFIVRYLADPLVGGFTTAAAFQVLVSQLKIVLNVSTKNYNGVLSIIYTLIEIFQNIGDT----NIADFIAGLLTIIVCMAVKELNDRFK--HKIPVPIPIEVIVTIIATAISYGANLEANYNAGIVKSIPSG-----FLPPVLPSVGLFSDMLAASFSIAVVAYAIAVSVGKVYATKHDYIIDGNQEFIAFGISNVFSGFFSCFVATTALSRTAVQESTGGKTQVAGLISAVIVMVAIVALGKLLEPLQKSVLAAVVIANLKGMFMQVCDVPRLWKQNK--TDAVIWVFTCIMSIILGLDLGLLAGLLFGLLTVVLRVQFPSWNGLGSVPSTDIYKSITHYK-----------NLEEPEGVKILRFSSPIFYGNVDGFKKCVKSTVGFDAIRVYNKRLK-----------ALRRIQKLIKKGQLRATKNGIISDVGS--SNNAFEPDEDVEEPEELDIPTKEIEIQVDWN----------SELPVKVNVPKVPIHSLVLDCGAVSFLDVVGVRSLRMIVKEFQRIDVNVYFALLQDDVLEKMEQCGFFDDN--IRKDRFFLTVHDAILYLQNQAKSREGQDSLLETITLIQDCKDPLELMEAEINEEELDVQDEAMRRLAS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43511-1", "uniprot_id": "S26A4_HUMAN", "id": "O43511-1", "name": "Pendrin", "aln": "-----------------MAAPGGRSEPPQLPEYSCSYMVSRPVYS------------------ELAFQQQHERRLQERKTLRESLA-KCCSCSRKRAFGVLKTLVPILEWLPKYRVKEWLLSDVISGVSTGLVATLQGMAYAL-LAAVPVGYGLYSAFFPILTYFIFGTSRHISVGPFPVVSLMVGSVVLSMAPDEHFLVSSSNGTVLNTTMIDT--------------AARDTARVLIASALTLLVGIIQLIFGGLQIGFIVRYLADPLVGGFTTAAAFQVLVSQLKIVLNVSTKNYNGVLSIIYTLVEIFQNIGDT----NLADFTAGLLTIVVCMAVKELNDRFR--HKIPVPIPIEVIVTIIATAISYGANLEKNYNAGIVKSIPRG-----FLPPELPPVSLFSEMLAASFSIAVVAYAIAVSVGKVYATKYDYTIDGNQEFIAFGISNIFSGFFSCFVATTALSRTAVQESTGGKTQVAGIISAAIVMIAILALGKLLEPLQKSVLAAVVIANLKGMFMQLCDIPRLWRQNK--IDAVIWVFTCIVSIILGLDLGLLAGLIFGLLTVVLRVQFPSWNGLGSIPSTDIYKSTKNYK-----------NIEEPQGVKILRFSSPIFYGNVDGFKKCIKSTVGFDAIRVYNKRLK-----------ALRKIQKLIKSGQLRATKNGIISDAVS--TNNAFEPDEDIEDLEELDIPTKEIEIQVDWN----------SELPVKVNVPKVPIHSLVLDCGAISFLDVVGVRSLRVIVKEFQRIDVNVYFASLQDYVIEKLEQCGFFDDN--IRKDTFFLTVHDAILYLQNQVKSQEGQGSILETITLIQDCKDTLELIETELTEEELDVQDEAMRTLAS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z5Y9-1", "uniprot_id": "A0A8M6Z5Y9_DANRE", "id": "A0A8M6Z5Y9-1", "name": "", "aln": "-----------------MMDECFHEN---------DYLVSRPIYS------------------NQIFDQVHERRNQETQSLQERLS-RTFGHTDKWAVQKVKGLLPIMEWLPKYPVKQWLPGDVVSGVTTGLVCCLQGVAYAL-LTSVAPVYGLYSAFFPILTYFVLGTSRHISVGPFPVTCLMVGSVVLTLAPDEHFLR-SVNMTDVNETMVEDTLMEVD-------VEAREAQRVMVACTMTVLVGLMQVAMGLMQVGFLVRYLSDPLVGGFTTAAAFHVFISQIKTILSVPTHNHNGFFSFAYTLIDVGSNINQA----NMADLIAGLLTISIVMAVKEINTKFQ--HKIPVPIPIEVIVTVIASAISHVMDLNSQYGASIVHNLPRG-----FASPQPPNIELIGSILGSSFSTAVVGYAVAVSVAKVYAAKHDYTVNGNQELIAFGVSNIFGGCFSSFVASTALSRTAVQESTGGKSQVAGLISAVMVMIVILALGPFLQPLQKSVLAGIVIANLKGMFLQISEVPVLWRQNR--TDCFIWIASCLASVVLGLDVGLLAGLVFEMGTVVVRTQFPSCATLGNVPNTDIYKNMKDYK-----------KVDEIPGVKIFKCNSPIYFANIDYFKEKLRDEVGFDAVRVFKKRNK-----------ALKKIHKLIKKGKLQVTEAGLVPVASLGVENKGFENEPGHEMEKQASKTDSEVKIQVDWT----------SELPVSVSVPRVHIHSLVVDFSSVSFLDVVAAKSLKLVVKEFIRIGVSVYIAGCDGELVRKMEALSFFDEE--VNRDLLFLSVHDAILFIQHQNSIGYEDNPLAEKISQLQDDKEPLPFTDDEDLIETYDNQHLAIHGLSN---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9WVC8-1", "uniprot_id": "S26A3_MOUSE", "id": "Q9WVC8-1", "name": "Chloride anion exchanger", "aln": "-----------------MIEAIG-----------NQYVVARPVYS------------------TKTFGEEFKKTHRHHKTFLDHLK-GCCSCSSQKAKKIALSLFPIASWLPAYKIKEWLLSDIVSGISTGLVAVLQGLAFAL-LVNIPPAYGLYAAFFPVITYFFLGTSRHISVGPFPVLSMMVGVVVTRVVSDP------NASSELSSSSTEN--------------DSFIEEKVMVAASVTVLSGIIQLLLGVLQVGFVVIYLSESLISGFTTAAAIHVLVSQLKFMLQLPVPAYSDPFSIFKVLESVFTQIQKT----NIADLVTSVIILVVVFVFKEINQRYR--SKLPVPIPIELIMTVIATGVSYGCNFEDRFGVAVVGNMSLG-----FQPPITPSVEVFQDTIGDSFGIAIVGFAVAFSVASVYSLKYDYPIDGNQELIALGVSNIFTGAFKGFAGSTALSRSGVQESTGGKTQVAGLLSAVIVLIVIVAIGFLLQPLQKSVLAALALGNLKGMLMQFAEIGRLWKKDK--YDCLIWIMTFIFAIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANVGRSNIYKNKKNYA-----------EVYEPEGVKIFRCPSPIYFANIGFFKQKLIDAVGFSPLRILRKRNK-----------ALKKIRKLQKRGLIQMTPKGFICTSDG-FKDSDEELDNNQIEELDQPINTTDLPFDIDWN----------GDLPLNITIPKISLHSLILDFSAVSFLDVSSMRGLRTILQEFIRIKVDVYIVGTDDDFIDKLARCEFFDDE--VTDSIFFLTIHDAILHILMKKDYSTSKF----NSSQEKERKFDFTINTNGGLRNRECQVPVETKF------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q924C9-1", "uniprot_id": "S26A3_RAT", "id": "Q924C9-1", "name": "Chloride anion exchanger", "aln": "-----------------MIEAIG-----------NQYVVARPVYS------------------TKAFGEEFKKTYGHHKTFLDHLK-GCCSCSSQKAKKIALSLFPIASWLPAYKIKEWLLSDIVSGISTGLVAVLQGLAFAL-LVNIPPAYGLYAAFFPVITYFFLGTSRHISVGPFPVLSMMVGVVVTRVASGS------DTSPALSSSSAEN--------------DSMIEEKVMVAASVTVLSGIIQLLLGVLQIGFVVIYLSESLISGFTTAAAIHVLVSQLKFMLQLTVPAHSDPFSIFKVLESVFSQIQKT----NIADLVTSVIILVVVFVVKEINQRYR--SKLPVPIPIELIMTVIATGISYGCNFEQRFGVAVVGNMSLG-----FQPPITPSVEVFQDTIGDCFGIAIVGFAVAFSVASVYSLKYDYPIDGNQELIALGVSNIFTGAFKGFAGSTALSRSGVQESTGGKTQVAGLLSAVIVLIVIVAIGFLLQPLQKSVLAALALGNLKGMLMQFAEIGRLWKKDK--YDCLIWIMTFIFAIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANVGRSNIYKNKKNYA-----------DVYEPEGVKIFRCPSPIYFANIGFFKQKLIDAVGFNPLRILRKRNK-----------ALKKIRKLQKQGLIQVTPKGFICTSDG-FKDSDEELDNNQIEELDQPINTTDLPFEIDWN----------ADLPLNITIPKISLHSLILDFSAVSFLDISSMRGLRTILQEFIRIKVDVYIVGTDDDFIDKLARCEFFDDE--VTDSIFFLTIHDAILHIWMKKDYSTSKF----NSSQEKERKFDFTINTNGGLRNRECQVPVETKF------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9Q0J5-1", "uniprot_id": "A0A8M9Q0J5_DANRE", "id": "A0A8M9Q0J5-1", "name": "", "aln": "------------------MQPFG-----------RHYVVVRPLFS------------------EDSFAEQHERINRKRKTLRHHLK-DYFSCDAKRAKNAALSLFPFIGWMKDYKIKEWLLGDIVSGISTGLVAVLQGLAFSL-LASLPPGYGLYTAFFPAIIYFFLGTSRHLSVGAFPILSLMVGAVVTRLVP--------DEGPSFNITGFEG--------------LSLEQQRVLVASSVTFLMGAFQLVMGLLQVGFIVMYLSETLVSGFTTAAAVHILVSQLRFVLGLDFPGINGPLAIIYTLVEVFSRITST----NVADLVTSIAIMALVLIVKEINDRFK--SKLPVPIPIEVIMTVIACGVSYAFNFEERFDVVIVGEMVNG-----YESPVAPNLEVIEETAVEAFPMAIVGFAVAFSVAKVYSVKHDYTIDGNQELIAFGVSNMFGASFRSFAASTALSRTAIQESTGGKTQIAGILSAMMVLIVIVGVGFLLEPLPRSVLGALVIVNLKGMLMQFSELPFLWRNDR--PDFVTWMVTFMASLFLGLDLGLAVGIGAELFTVVYRTQFPRCSVLANISGTDLYRDRKDYTS---------IQIYEPDGVKIFKIPSPIFFANIDFFRDKLVQEVGFNPMRVLKKRNK-----------ALRKIRKMLCNGELEVSDRGPVLRQPS-VDTSE-----GSMEDLDQPIDFSDLPIQVNWN----------SQLPANISVPPVNIHSLILDFCAVSFIDVSALKGLKATLKEFIRIEVDVYIVSCDVYIMEKLQHCTFFDDE--IKTSIFYPTLHDAMLHILETHPD---------HGELEKDININYEVIQRDSLTV-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BU91-1", "uniprot_id": "S26A9_MOUSE", "id": "Q8BU91-1", "name": "Solute carrier family 26 member 9", "aln": "-----------------------------MNQPRPRYVVDRAAYS------------------LSLFDDEFEKKDRAYPVGEKLR--NTFRCSSAKFKAFVFGLLPVLSWLPKYKIKDYIIPDLLGGLSGGCIQVPQGMAFAL-LANLPAVNGLYSSFFPLLTYFFLGGIHQMVPGTFAVISILVGNICLQLAPESKFQIFNNVTNETYVDTAAM-----------------EAERLHVSATLACLTAVIQMALGFMQFGFVAIYLSESFIRGFMTAAGLQILISVLKYIFGLTIPSYTGPGSIVFTFIDICKNLPHT----NIASLIFALVSGVFLVLVKELNARYM--HKIHFPIPTEMIVVVVATAISGSCKMPKKYHMQIVGEIRQG-----FPTPVAPMVSQWKGMVGTAFSLAIVGYVINLAMGRTLASKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLAVDGAGGKSQVASLCVSLVVMITMLVLGSYLYPLPKAVLGALIAVNLKNSLKQLTDPYYLWRKSK--LDCCVWVVSFLSSFFLSLPYGVAVGVAFSILVVIFQTQFRNGSTLAQVMDTDIYVNPKTYN-----------RAQEIAGVKIVTYCSPLYLANSEIFRQKVIAKTGMDPQKVLLAKQKYLRKQEKRTAIPTQQRKSLFMKTKTVSLQELQQDFESAPSTDPNNNQAPAAEAHISYITFSPDASTAAACELPASTRSPQEASDTLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYEKIGVQIFLVNIHAQVYNDISHGGVFEDGC-VQRSHVFPSIHDAVLFAQANAREA-PDRNFHGAPGDTEFSLYDSEEEGPSYWDLEQEMFGTMFHTETLTAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZV32-1", "uniprot_id": "D3ZV32_RAT", "id": "D3ZV32-1", "name": "", "aln": "-----------------------------MSQTRPRYVVDRAAYS------------------LSLFDDEFEKKDRAYPVGEKLR--NTFRCSSAKLKAIVFGLLPVLSWLPKYKIKDYIIPDLLGGLSGGCIQVPQGMAFAL-LANLPAVNGLYSSFFPLLTYFFLGGIHQMVPGTFAVISILVGNICLQLAPESKFQIFNATTNETYVDTVAM-----------------EAERLHVSATLACLTAVIQMALGFMQFGFVAIYLSESFIRGFMTAAGLQILISVLKYIFGLTIPSYTGPGSIVFTFIDICKNLPHT----NIASLVFALVSGVFLVLVKELNARYM--HKIHFPIPTEMIVVVVATAISGSCKMPKKYHMQIVGEIRHG-----FPIPVAPMVSQWKDMVGTAFSLAIVGYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLAVDGAGGKSQVASLCVSLVVMITMLVLGSYLYPLPKAVLGALIAVNLKNSLKQLTDPYYLWRKSK--LDCCVWVVSFLSSFFLSLPYGVAVGVAFSILVVIFQTQFRNGSTLAQVMDTDIYVNPKTYN-----------RVQEIEGVKIVTYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLRKQEKRMAVPTQQRKSLFMKTKTVSLQELQQDFESAASTDPNNNQAPVADAHISYITFSPDSSATAASELPTSTQSPREASDALASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYEKIGVQIFLVNIHAQVYNDISQGGIFEDGC-VQRNHVFPSIHDAVLFAQANAREA-PAHNFQGAPGDTEFSLYDSEEDGSSYWDLEQEMFGTMFHTETLTAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7LBE3-1", "uniprot_id": "S26A9_HUMAN", "id": "Q7LBE3-1", "name": "Solute carrier family 26 member 9", "aln": "-----------------------------MSQPRPRYVVDRAAYS------------------LTLFDDEFEKKDRTYPVGEKLR--NAFRCSSAKIKAVVFGLLPVLSWLPKYKIKDYIIPDLLGGLSGGSIQVPQGMAFAL-LANLPAVNGLYSSFFPLLTYFFLGGVHQMVPGTFAVISILVGNICLQLAPESKFQVFNNATNESYVDTAAM-----------------EAERLHVSATLACLTAIIQMGLGFMQFGFVAIYLSESFIRGFMTAAGLQILISVLKYIFGLTIPSYTGPGSIVFTFIDICKNLPHT----NIASLIFALISGAFLVLVKELNARYM--HKIRFPIPTEMIVVVVATAISGGCKMPKKYHMQIVGEIQRG-----FPTPVSPVVSQWKDMIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPYYLWRKSK--LDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTDIYVNPKTYN-----------RAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQEKRRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSSSPAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGKIGVKVFLVNIHAQVYNDISHGGVFEDGS-LECKHVFPSIHDAVLFAQANARDVTPGHNFQGAPGDAELSLYDSEEDIRSYWDLEQEMFGSMFHAETLTAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CIW6-1", "uniprot_id": "S26A6_MOUSE", "id": "Q8CIW6-1", "name": "Solute carrier family 26 member 6", "aln": "-----MGLPDGSDQGTHQTQALLSAAQEMELQRRD-YHVERPLLN------------------QEQLEDLGHWG--PAAKTHQWR--TWFRCSRARAHSLLLQHVPVLGWLPRYPVREWLLGDLLSGLSVAIMQLPQGLAYAL-LAGLPPMFGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLTAD--------KAFVQGLNATA------------------DDARVQVAYTLSFLVGLFQVGLGLVHFGFVVTYLSEPLVRSYTTAASVQVLVSQLKYVFGIKLSSHSGPLSVIYTVLEVCAQLPET----VPGTVVTAIVAGVALVLVKLLNEKLH--RRLPLPIPGELLTLIGATGISYGVKLNDRFKVDVVGNITTG-----LIPPVAPKTELFATLVGNAFAIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGFFQCFPVSCSMSRSLVQESTGGNTQVAGAVSSLFILLIIVKLGELFRDLPKAVLAAVIIVNLKGMMKQFSDICSLWKANR--VDLLIWLVTFVATILLNLDIGLAVSIVFSLLLVVVRMQLPHYSVLGQVPDTDIYRDVAEYS-----------GAKEVPGVKVFRSSATLYFANAELYSDSLKEKCGVDVDRLITQKKKRIKKQE-MKLKRMKKAKKSQKQDASSKISSVSVNVNTNLEDVKSNDVEGS-EAKVHQGEELQDVVSSNQED-----AKAPTMTSLKSLGLPQPGFHSLILDLSTLSFVDTVCIKSLKNIFRDFREIEVEVYIAACYSPVVAQLEAGHFFDES--ITKQHVFASVHDAVTFALSHRKSV-----------------------------PKSPVLATKL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z9I5-1", "uniprot_id": "D3Z9I5_RAT", "id": "D3Z9I5-1", "name": "", "aln": "----------------------------MELERRD-YHVERPLLN------------------QEQLEDLGHWG--PVSKTHPWR--TWFRCSRARAKSLLIQHVPVLGWLPRYPVREWLLGDLLSGLSVAIMQLPQGLAYAL-LAGLPPMFGLYSSFYPVFVYFLFGTSRHISVGTFAVMSVMVGGVTESLTAD--------EAFVQSLNTTV------------------DGARVQVAYTLSFLVGLFQVGLGLVHFGFVVTYLSEPLVRSYTTAASVQVLVSQLKYVFGIKLNSHSGPLSVIYTVLEVCAQLPKT----VPGTVVTAIVAGVVLVLVKLLNEKLR--RRLPLPIPGELLTLIGATAISYGVKLNDRFKVDVVGNITTG-----LIPPVAPKTELFATLVGNAFAIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGFFQCFPVSCSMSRSLVQESTGGNTQIAGAVSSLFILLIIVKLGELFRDLPKAVLAAVIIVNLKGMMKQFSDICSLWKANR--VDLLIWLVTFVATILLNLDIGLAVSIVFSLLLVVIRMQLPHYSVLGQVPDTDIYRDVAEYS-----------GAKEVPGVKVFRSSATMYFANAELYSDSLKKKCGVDVDRLITQKKKRIKKQE-MKIKRMNKAKKSQKQAASSKISSVSVNVNTNFEDIKSNDVEGS-EAKVHQGEELEDVVASNQED-----AKPPIMTSLKALGLPQPDFHSLILDLSTVSFVDTVCIKSLKNIFRDFREIEVEVYIAACYSPVVTQLEAGHFFDES--ITKQHVFASVHDAVTFALHHRKSG-----------------------------PKSPVLATKL--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BXS9-1", "uniprot_id": "S26A6_HUMAN", "id": "Q9BXS9-1", "name": "Solute carrier family 26 member 6", "aln": "-----MGLADAS--GPRDTQALLSATQAMDLRRRD-YHMERPLLN------------------QEHLEELGRWG--SAPRTHQWR--TWLQCSRARAYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYAL-LAGLPPVFGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQ--------ALNDSMINETAR-----------------DAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQS----KVGTVVTAAVAGVVLVVVKLLNDKLQ--QQLPMPIPGELLTLIGATGISYGMGLKHRFEVDVVGNIPAG-----LVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANR--ADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYS-----------EAKEVRGVKVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQAASPKGASVSINVNTSLEDMRSNNVEDCKMMQVSSGDKMEDATANGQED-----SKAPDGSTLKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGHFFDAS--ITKKHLFASVHDAVTFALQHPRPV-----------------------------PDSPVSVTRL--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A9C3T3-1", "uniprot_id": "A9C3T3_DANRE", "id": "A9C3T3-1", "name": "", "aln": "-----------------------MEEDMKELRKRVPYHIQREVLD------------------ELSVDQVAEKSDFNISVKEKLK--DAVRCTGPKAKSCFLSFIPLLAWLPKYPFRENAIGDLISGISVGIMHLPQGMAYAL-LAAVPPVFGLYSSFYPILIYFIFGTSKHISVGTYAVMSVMIGSVTERLAPDSDFTFPGNETNSTYIDFSSR-----------------DAERVKIAATVTFLSGIFQLLLGVVRFGFVVTYLSEPLVRSYTTAAAIHVIVSQLKYSFGINPHRYSGPLSLIYTVIEICALLGKT----NIGTLVVSIVTIVGLIIAKELSALAA--KKIPIPIPVELITIIIATVVSWYMDLKTIYKVEVVGEIPSG-----LQAPVAPKVSQLGSMVGDAFALAVVGYGIAISLGRIFALKYAYKVDSNQELIALGLSNSIGGLFSCFAISCSMSRSMVQVSTGGKSQVAGAISALVILVILLKIGELFEELPKAVLAAIIYVNLQGMMKQFGDICSLWRTNK--VDMVVWVMTMILTILFNPDMGLAASIAFSILTVVFRTQLPKYSILGQIPGTDIYKPVEDYN-----------QVKEIPGITIFRSSATLYFANAEMYIDALYEKTGVDVAKLLSHKKKLQAKRLRKEKKAAKKAKKEAKKRA--KEAARQAKEEPVFSDTEESEEEPELVSHSQTNGNVHELSVKEPKD-----MVVVEAGPYTDPDTPLP--KAIILDLNPVNFLDTVGVKTLRNIYKDYGEAGVQIYLCGCQRGVVESMEKGDFFNEK--VTKSILFSTVHDAVLYCQQGNN--------------------------------EKVMQGTHL--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7T2C4-1", "uniprot_id": "S26A5_DANRE", "id": "Q7T2C4-1", "name": "Prestin", "aln": "---------------------MEHVTVSEEPSATLMYHVERPIFS------------------EAYIDSELLHKRKKTPKPYKLRVAEHLCCSSEKVKSVVFGFLPILTWLPSYPLKEYLFGDIVSGISTGVMQLPQGLAYAM-LAAVPPVFGLYSSFYPVLLYTFFGTSKHISIGTFAVISLMIGGVAVREAPDSMFMVNG-TNSSLVVNIEAR-----------------DSRRVEVVVALTTLVGIIQFVLGLLRFGFLAIYLTEPLVRGFTTAAAVHVSVSQLKYLLGVKTARFNGPLSVVYSLDAVLRNIADT----NIVTLIIGLGCTVFLYIIKQLNERFK--KKLLIPIPGEIIVVIVSTGISYGMLMSENYGVDVVGKIPTG-----LLPPKVPDFSVFPNLFADAVPIAVVGFSITISLAKTFALKYGYSVDGNQELIALGLCNFVSSFFHTFVVTASMSRSLVQESTGGHTEIAGLLASLLVLLVVVAIGFVFQPLPTTVLAAIIMVNLLGMFKQTRDIPVLWRKSK--IELAIWLVSFFASVLLGLDYGLAVAMAFAILTVIYRTQRPKNVVLGQIPDTGLYFDVDEYE-----------EAEECSGIKIFQSNSSIYFANSELYVKALKAKTGIDPEKLLDAKKLQLKYAK----RDTEGTKTVNQGSLLKKNAVVLLDMELGVTHEVLNGPQKP--KHVHTNGQMTEKHIESESE-----DEFFLQR--------LTPIHSVILDFTPVNFIDSVGAKTIKSVIKEYATVDVKVVLAGCSRTLLSELRTLQFFSEP--VTPDLIFPTIHDAVLQCKRWRDLP-----------------------------VHPNIH------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P58735-1", "uniprot_id": "S26A1_MOUSE", "id": "P58735-1", "name": "Sulfate anion transporter 1", "aln": "----------------MDASPEPQQKGG-----------------------------------TLVLVRRQPPVSQGLLETLKARLKKSCTCSMPCAQALVQGLFPAIHWLPQYRLKEYLAGDVMSGLVIGIILVPQAIAYSL-LAGLQPIYSLYTSFFANLIYFLMGTSRHVNVGIFSLLCLMVGQVVDRELQLAGFD--PSQDSLGPKNNDSTLNNSATTLIIGLQDCRRDCYAIRVATALTLMAGLYQVLMGILRLGFVSTYLSQPLLDGFAMGASVTILTSQAKHMLGVQIPRHQGLGMVVHTWLSLLQNVGQA----NICDVVTSALCLGVLLAAKELSDRYR--HRLKVPIPTELFVIVVATIVSHFGQLHTRFDSRVAGNIPTG-----FVAPQVPDPKIMWRVALDAMSLALVGSAFSISLAEMFARSHGYSVSANQELLAVGCCNVLPAFFHCFATSAALSKTLVKIATGCQTQLSSVVSAAVVLLVLLVLAPLFHDLQRCVLACIIVVSLRGALRKVKDLPQLWRLSP--ADALVWVATAATCVLVSTEAGLLAGVFFSLLSLAGRTQRPRAALLARIGDSTFYEDAAEFEG-----------LLPPPEVRVFRFTGPLYYANKDFFLRSLYRLTGLDAGHSATRKDQ----------------------------------------GPEVGVSNRSLVDGKDLGSVSSGAGLVVPLA---------------------FGFHTVVIDCAPLLFLDVAGMATLKDLRRDYRALDITLLLACCSPSVRDTLRKGGFLGEEQGAENELLFPSVHSAVEAACARR--------------------------------EELLAADSAL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P45380-1", "uniprot_id": "S26A1_RAT", "id": "P45380-1", "name": "Sulfate anion transporter 1", "aln": "----------------MDASPEPPQKGG-----------------------------------TLVLVRRQPPVSQGLLETLKARLKKSCTCSMPCAQALVQGLFPVIRWLPQYRLKEYLAGDVMSGLVIGIILVPQAIAYSL-LAGLQPIYSLYTSFFANLIYFLMGTSRHVNVGIFSLLCLMVGQVVDRELQLAGFD--PSQDSLGPGNNDSTLNNTAT-LTVGLQDCGRDCHAIRIATALTLMAGLYQVLMGILRLGFVSTYLSQPLLDGFAMGASVTILTSQAKHLLGVRIPRHQGLGMVIHTWLSLLQNVGQA----NLCDVVTSAVCLAVLLTAKELSDRYR--HYLKVPVPTELLVIVVATIASHFGQLHTRFGSSVAGNIPTG-----FVAPQIPDPKIMWSVALDAMSLALVGSAFSISLAEMFARSHGYSVSANQELLAVGCCNVLPAFFHCFATSAALSKTLVKIATGCQTQLSSVVSAAVVLLVLLVLAPLFHDLQRCVLACIIVVSLRGALRKVKDLPQLWRLSP--ADALVWVATAATCVLVSIEAGLLAGVFFSLLSLAGRTQRPRAALLARIGDSTFYEDAAEFEG-----------LLPPPEVRVFRFTGPLYYANKDFFLRSLYSLTGLDAGYSATRKDR----------------------------------------GTEVGVSNRSLVDRKDLGSVSSGDGLVVPLA---------------------FGFHTVVIDCAPLLFLDVAGMATLKDLRKNYRALDITLLLACCSPSVRDTLRKGGFLGEDQGTAEELLFPSVHSAVETACARR--------------------------------EELMAADSAL--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50443-1", "uniprot_id": "S26A2_HUMAN", "id": "P50443-1", "name": "Sulfate transporter", "aln": "--------MSSESKEQHNVSPRDSAEGNDSYPSGIHLELQRESSTDFKQFETNDQCRP----YHRILIERQEKSDTNFKEFVIKKLQKNCQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSL-LAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGETVDRELQKAGYDNAHSAPSLGMVSNGSTLLNHTS-----DRICDKSCYAIMVGSTVTFIAGVYQVAMGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFRNIHKT----NLCDLITSLLCLLVLLPTKELNEHFK--SKLKAPIPIELVVVVAATLASHFGKLHENYNSSIAGHIPTG-----FMPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLFYSLQKSVLGVITIVNLRGALRKFRDLPKMWSISR--MDTVIWFVTMLSSALLSTEIGLLVGVCFSIFCVILRTQKPKSSLLGLVEESEVFESVSAYKN-----------LQIKPGIKIFRFVAPLYYINKECFKSALYKQT-VNPILIKVAWKK----------------------------------------AAKRKIKEKVVT----LGGIQDEMSVQLSHDP--------------------LELHTIVIDCSAIQFLDTAGIHTLKEVRRDYEAIGIQVLLAQCNPTVRDSLTNGEYCKKE---EENLLFYSVYEAMAFAEVSKN-------------------------------QKGVCVPNGLSLSSD---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1W2Q625-1", "uniprot_id": "A0A1W2Q625_RAT", "id": "A0A1W2Q625-1", "name": "Anion exchange transporter", "aln": "-------------------------------------------------------------------------MTGAKRKKRSVLWGKMHTPHREDIKQWCKRRLPILEWAPQYNLKENLLPDTVSGVLLAVQQVTQGLSFAI-LSSVHPVFGLYGSLFPAIIYAIFGMGRHVATGTFALTSLISANAVERLVPQSNRNLTTQSNSSVLG------------------LSEFELQRIGVAAAVSFLGGVIQLVMFVLQLGNATFLLTEPVISAMTTGAATHVVTSQVKYLLGIKMPYISGPLGFFYIYAYVFENIKSV----QLEALLLSLLSIVVLVLVKELNEQFK--RKIKVVLPVDLVLIIAASFACYCTNMENTYGLEVVGRIPKG-----IPPPRAPPMNILSAVLTEAFGVALVGYVASLALAQGSAKKFKYSVDDNQEFLAHGLSNVIPSFLFCIPSAAAMGRTAGLYSTGAKTQVACLISCIFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDLKKYWNVDK--IDWGIWISTYIFTICFAANVGLLFGVVCTIAIVLGRFPRAKTLSITDMKEMELKVKTETYD-------------ENSQQIKIISINNPLVFLNAKKFSADLMKIILKETDGSQ-------------------------------------------ALDDVSKCEQNTLLSPLPNGSCTEEASQPCPSE-----------------------KYSLVLNCSGLTFFDYTGVSTLVELYLDCKSRSVDVFLANCTASLIKAMTYYGDLDTEK----PIFFDSVATAISVIQSNKNLS-------------------------------KDTDHSEV--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53394-1", "uniprot_id": "SULX_YEAST", "id": "P53394-1", "name": "Putative sulfate transporter YPR003C", "aln": "MTSNNSLLGRGRMSYSSTAPPRFKRSVDQRDTFSDNFDYDKDSSNRGRTYIAASNSTTGVPPPNNSRSGCTNNTNNTNNTSNTSNTNNNDSVDENTVFETLPYYLPCFSWLPEYTFNK-LWGDVIAGISVASFQIPLALSYTTSIAHVPPLCGLYSLAISPFVYGILGSVPQMIVGPESAISLVVGQAVESITLHKEN-----------------------------------VSLIDISTVITFVSGTILLFSGISRFGFLGNVLSKALLRGFISSVGLVMIINSLISELKLDKFLVSLPQHYHTPFEKILFLIDYAPAQYHIPTAIFSGCCLIVLFLTRLLKRKLMKYHKSAIFFPDILLVVIVTILISMKFNLKHRYGISIIGDFSMDNFDELKNPLTRPRRKLIPDLFSASLIVAMLGFFESTTASKSLGTTYNLTVSSNRELVALGFMNIVISLFGALPAFGGYGRSKINALSGAQSVMSGVFMGVITLITMNLLLQFVHYIPNCVLSVITTIIGISLLEEVPGDIKFHLRCGGFSELFVFAVTFCTTIFYSIEAGICIGCVYSIINIIKHSAKSRIQILARVAGTSNFTNLDDYMMNMKRNSLDVEGTEEIEGCMIVRIPEPLTFTNSEDLKQRLDRIERYGSSKIHPGRKS-----------------------------------------LRSKDSIKYVIFDLGGMTSIDSSAAQVLEE-------------------------IITSYKRRNVFIYLVNVSINDKVRRRLFKAGVAASVERAQANNNENNTSNTFSDAG--ETYSPYFDSIDAALYEIEKMKIKG----------------------NNVPNNDSESFMSNTLFNSSLV---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* * * ... * :.*: . .:::: : .** . : * .:* :: * .:: . : : :: : . . :.* *:...: . ... : . : : : : . : :. .* :. : : . : : : : . * .. :::. : . . . :. *:*: * * * . . : . . : :* :: :: . :: : : . : **. : . : : : : : *: . : : : : : : :. .: * : : *. : . : :: *: ", "identical_positions": 26, "similar_positions": 125, "identity": "2.94%" }, { "cls_id": "homologset.agr.SGD:S000006208", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P13803-1", "uniprot_id": "ETFA_RAT", "id": "P13803-1", "name": "Electron transfer flavoprotein subunit alpha, mitochondrial", "aln": "MFR--AAAPGQLRRAASLLR-FQSTLVIAEHAND-SLAPITLNTITAAGRLGGEVSCLVAGTKCDKVVQDLCK---VAGVAKVLVAQHDAYKGLLPEELTPLILETQKQFSYTHICAGASAFGKNLLPRVAAKLNVAPVSDIIEIKSPDTFVRTIYAGNALCTVKCDEKVKVFSVRGTSFEAAAA-SGGSASSEKAPS-SSSAGISEWLDQKLTKSDRPELTGAKVVVSGGRGLKSGENFK-LLYDLADQLHAAVGASRAAVDAGFVPNDMQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADYGIVADLFKVVPEMTEILKKK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LC5-1", "uniprot_id": "ETFA_MOUSE", "id": "Q99LC5-1", "name": "Electron transfer flavoprotein subunit alpha, mitochondrial", "aln": "MFR--AAAPGQLRRAASLLR-FQSTLVIAEHAND-SLAPITLNTITAAGRLGGEVSCLVAGTKCDKVVQDLCK---VAGVAKVLVAQHDAYKGLLPEELTPLILETQKQFSYTHICAGASAFGKNLLPRVAAKLNVAPVSDIIEIKSPDTFVRTIYAGNALCTVKCDEKVKVFSVRGTSFEAAAT-SGGSASSEKAPS-SSSVGISEWLDQKLTKSDRPELTGAKVVVSGGRGLKSGENFK-LLYDLADQLHAAVGASRAAVDAGFVPNDMQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADYGIVADLFKVVPEMTEILKKK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13804-1", "uniprot_id": "ETFA_HUMAN", "id": "P13804-1", "name": "Electron transfer flavoprotein subunit alpha, mitochondrial", "aln": "MFR--AAAPGQLRRAASLLR-FQSTLVIAEHAND-SLAPITLNTITAATRLGGEVSCLVAGTKCDKVAQDLCK---VAGIAKVLVAQHDVYKGLLPEELTPLILATQKQFNYTHICAGASAFGKNLLPRVAAKLEVAPISDIIAIKSPDTFVRTIYAGNALCTVKCDEKVKVFSVRGTSFDAAAT-SGGSASSEKASS-TSPVEISEWLDQKLTKSDRPELTGAKVVVSGGRGLKSGENFK-LLYDLADQLHAAVGASRAAVDAGFVPNDMQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADYGIVADLFKVVPEMTEILKKK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KN94-1", "uniprot_id": "ETFA_DROME", "id": "Q7KN94-1", "name": "Electron transfer flavoprotein subunit alpha, mitochondrial", "aln": "MF---ASNTRNLMRSSILQR-CKSTLVVAEHNNE-VLNPITLNTISAAKKIGGDVTVLVAGTKCGPASEALSK---VDGVTKVLVAENAAFNGFTAESLTPLVLAAQSQFKFTHILAGASAFGKNVLPRVAAKLDVSPISEIIDVKSDDTFVRTIYAGNAILTLKSKDAVKVITVRSTNFPPAAT-SGGSGAVEQAPAGDFASSLSEFVSQELTKSDRPELAGAKVIVSGGRGLKSGDNFK-LLYDLADKFGAAVGASRAAVDAGFVPNDLQIGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADIGIVADLFKAVPELTGKL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12480-1", "uniprot_id": "ETFA_YEAST", "id": "Q12480-1", "name": "Electron transfer flavoprotein subunit alpha, mitochondrial", "aln": "MFKSLAAVLPRASKAKFLQKNYASTLAFIESSKDGSVSRSSLSLLAAAQKLSNPITAVITGSKAEKTAEALKSSYSCSNLEKLVIFEDSKLDTCLPEQLTPLLVKLLKGGDYSHFVVSNSSVGKSVLPRVGALLDVQPVCEVTVIKDPKTFIRPIYAGNIISTIECQAEKKLLIIRASAFPPIAEGSMDSVTIEKRTDIPPCDLNVTWVKTILTKSERPELTSAQNVVTGGRALKDKETFEKLLSPLADVLHAAIGATRASVDNGLCDNSLQIGQTGKVVAPNLYIAIGVSGAVQHLAGMKDSKVIVAINNDPDAPIFNVADYGLQGDLYKIVPELTEKLGKYK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *: . :: * : ***.. * :: : :*. ::** ::.. :: :::*:*. . : * . .: *::: :. . .*.****:: . .::*: .. *:.**.:****.* *:* *:.:: :*. .**:*.***** : *::.. *:: :*.: * . * * .* : *: . ::. ****:****:.*: :*:***.**. :.*: ** *** : **:**:**:** *: *.:*:*****:***:****:*:***:**********.*****:**:****:*** *: .**:* ***:* * ", "identical_positions": 130, "similar_positions": 112, "identity": "37.79%" }, { "cls_id": "homologset.agr.SGD:S000006211", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYJ4-1", "uniprot_id": "REC8_RAT", "id": "Q6AYJ4-1", "name": "Meiotic recombination protein REC8 homolog", "aln": "--MFYYPNVLQRHTGCFATIWLAATRGSRLVK--------REYLKVNVVKTCEEILNYVLVRVQPPMPGLP--RPRFSLYLSAQLQIGVIRVYFQQCQYLVEDIQHILEHLHRA--------QLRIRID-MEEADLPSLLLPNCLAMMETLEDAPEPFFGTMSVDPTLPSPFDIPQIRHLLEAATPEKIREETLPEATPEPRKPDRTLAMVQSPEVITLQEAEPIRMLRIE----GEQDLPEISRGDLDLLIAE----EDDAILLEERQRGRLLRQRRASPPLDESKEEPRALEGDGLVSSLSPPAPAQVEGIREPLPDQAFPPEVQKMPGWEPGVLLTEVTPPQELRLPAPPSIEKRPPSPQRPPRRRRRGRQLL---FWDKETQISREKFEEQLQTGAHCCEYP--VVQPPKRKLMSPAELFRTPTLSGWLSPELLALWTHCAQVPPRMLRQRPQLETEETVEEERVADKEERRKTEALSEIEVLREAQEPSGPLMLSSELSLEVAEEEKSRTS-------------------FIPPEERWAWIE-------ERQPEPPALPMLPELPEVPMEMP----PGPELLSSEAVLRAVALELQANREPDFSSLVPPLS----------------SRKLASRVFYLLLVLSAQKILLVDQQKPYGRLLIRLGPKFP-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C5S7-1", "uniprot_id": "REC8_MOUSE", "id": "Q8C5S7-1", "name": "Meiotic recombination protein REC8 homolog", "aln": "--MFYYPNVLQRHTGCFATIWLAATRGSRLVK--------REYLNVNVVKTCEEILNYVLVRVQPPVAGLP--RPRFSLYLSAQLQIGVIRVYFQQCQYLVEDIQHILEHLHRA--------QLRIRID-MEEADLPSLLLPNCLAMMETLEDAPEPFFGKMSVDPRLPSPFDIPQIRHLLEAATPEKTRKETLPEATPDPRKPDRTLATVQSPEVITLQEAEPIRMLQIE----GEQDLPEISRGDLELLIAE----KDDAILLEERQRGRLLRQRRASLPLDESREEPRALEGAGLVSALSPPAPAQVEGIQEALPGQVFPPEVQKMTGWEPGALLTEVTPPQELRLPAPPSTEKRLPSLQRPLPRRHRRRQLL---FWDKETQISREKFEEQLQTGAHCWEYP--VAQPPKRMLTSPAELFRTPTLSGWLPPELLGLWTHCAQVPQRMLRQRPQLETEETVEEERAADEEERRKTEALSEIEVLREAQEPSGPLMLSSELSLEAAEDEKSRTS-------------------LIPP-EWWAWSE-------EGQPEPPALPMLPELPEVPMEMP----PRPE-LSSEAVLRAVALKLQANKELDFSSLVPPLS----------------PRKLASRVFYLLLVLSTQKILLVEQQKPYGPLLIRPGPKFP-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95072-1", "uniprot_id": "REC8_HUMAN", "id": "O95072-1", "name": "Meiotic recombination protein REC8 homolog", "aln": "--MFYYPNVLQRHTGCFATIWLAATRGSRLVK--------REYLRVNVVKTCEEILNYVLVRVQPPQPGLP--RPRFSLYLSAQLQIGVIRVYSQQCQYLVEDIQHILERLHRA--------QLQIRID-MET-ELPSLLLPNHLAMMETLEDAPDPFFGMMSVDPRLPSPFDIPQIRHLLEAAIPERV-EEIPPEVPTEPREPERIPVTVLPPEAITILEAEPIRMLEIE----GERELPEVSRRELDLLIAE----EEEAILLEIPR--------------------------------LPPPAPAEVEGIGEALG-----PEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVP--PPPRRRRRRRLL---FWDKETQISPEKFQEQLQTRAHCWECP--MVQPPERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQPPPKALRR--------ELPEEAAAE-EERRKIEVPSEIEVPREALEPSVPLMVSLEISLEAAEEEKSRIS-------------------LIPPEERWAWPE-------VEAPEAPALPVVPELPEVPMEMPLVLPPELELLSLEAVHRAVALELQANREPDFSSLVSPLS----------------PRRMAARVFYLLLVLSAQQILHVKQEKPYGRLLIQPGPRFH-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TGX4-1", "uniprot_id": "A0AB32TGX4_DANRE", "id": "A0AB32TGX4-1", "name": "", "aln": "--MFYYPNVLQRHTGCFSTIWLAATKGIRISR--------RDYLKVNVRRTCEDIVDYVMVQVPPVHPSLP--RPRFSLYLSSQLQYGVIIVYHRQCAFLLEEVQQTIERLLRS--------KRHLNID-MPDNDRLVLNVPDSLFQLEEAEWALEPFFGVMGVD-CVPSPCLSSQQ--FMSASSPLTHTKEITSPKG-----------LVASPETITIKDAELVPVLAAEF---GGAELPEATAHEIDLLMEQ----QDQFHLEDEDKERERVADAEKSGSLDP-------------AMVSIEQLKNSECLMDEGNGRFTEVTLDRVALEMTPPPITMTTTTDASERDVEMESSETLTAEQSVPLKRRGRKRQLI---FADQNTQISQDAMRQQINNPLTETQSLSDVLQSIPASRKASAAVLLSTPCNLLIHPDLQTLWKSCSVSSTLSRPSRKRQAKKESELMEREKERGVERSRESSREVIRESEAALVLSESSAASDVPLDVSKGDRSPSD-------------------LITPNSRWSPIE-------EAP--VSMEVILEEHVDLPLGEA---ELEMSDIITEDLFRLITGFIECRGKVGFHSLLPPEA----------------DRSTVAHLFYQILELLCDLKLSAHQTEAFGVITFTTER----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12188-1", "uniprot_id": "REC8_YEAST", "id": "Q12188-1", "name": "Meiotic recombination protein REC8", "aln": "MAPLSLNFKDDKKYKGLTTVWLLSALGNSIVKESNNYYSNKSNSTGNISSSTVKKKDIVNISIPKTCDEIQNFENDFSLRYISNLLYGVTICYNKKTEYVLNDLNHLLVQLQKNDVYAFKAKNKSTRINGLNSNNSIIGNKNNNYTWEECVFFDDDPLYDITKVPALEFLNTTLQDNVSFIEEAKSIRRQDYINELSNSNRFELHGDMTNSDAQSNLGSNVRNSFPLDEIPVDVDFNLDLDDIVSHQGTPLGSHSSSQKDGNDFKFNYQGDELVLNFENDNENNSNGGEDTSVENEGPVANLKDYELGLEAQASEEENDLQQKLNTRMQRGHRADVGGQFSKVQFDAKTSYPNEVLKFNHGNYSHLMEKNRIRKLTGQNFLTSNISSLVRSCGEEEFFSTNWLSIFNDFSNIKTSEWDLYPQGFSSVERGRKRAHSLVSTQSSSSTRSHEYGRKSFRNNKNDNYSSDMENDNLLLNLEQINEDLEDGHYIEENSQGNILDFNLNLPPSSFGRSHTRNSTRSSGFNEDIVGALRRRVGPSEQNFAEEDDSSNSCFSDGSQQNLQQDKTNFQDVILDYQTKKFYDYIKERSIVVGRTTRSNPPFKRKMLLVDIIPSRMGEAQTGANFDDVERGVSRQIAASAFLSLLNLATKGMVKLNEYPVADAVTKDLKLRREDEIIVYA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::: ::*:** :: * : : :. *: : . : * : : : . *** ::* ** * :: :::::::: : :* : : .*: : : : * :*::. * : ::. : . . . . : : . : :* : : * . :: : : * . . . : . .: * *:* * .: . :: . . : . : : . .* . .: . : : . : :: :: * :. :* . .. . :: : : :: : : * . : : .::.. * .: * :* * . : .: . : ", "identical_positions": 33, "similar_positions": 132, "identity": "4.85%" }, { "cls_id": "homologset.agr.SGD:S000006214", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54888-1", "uniprot_id": "RPA2_RAT", "id": "O54888-1", "name": "DNA-directed RNA polymerase I subunit RPA2", "aln": "-MDVDSRWRNLPSGPSLKHLTDPSYAVPPEQQK---AALQDLTRAHVDSFNYAVLEGLS-----------------HAVQAIPPFEFAFK---DERISLTIVDAAISPPAVPKGTI-CKELNIYPAECRGRRSTYRGKLTADISWAVN-GVPKGIIKQFLGXVPIMVKSKLCNLYNLPPQVLIEHHEEAEEMGGYFIINGIEKVIRMLIMPRRNFPIAMIRPKWKSRGLGYTQFGVSIHCVREEHSAVNMNLHYVENGTVMLNFIYRKELFFLPLGFALKALVSFSDYQIFQELIKGKEEDSFFKNSVSQMLRIVMEEGCHTQ--KQVLDYLGERFRVKL-SLPDWYPNAEAAEFLFNQCICIHLKSN--TDKFYLLCLMTRKLFALARGECMEDNPDSLVNQEVLTPGQLFLMFLKEKMENWLLSIKIALDKRAQKTNVSINNEN---LMKIFSMGTELTRPFEYLLATGNLRSKTGLGFMQDSGLCVVADKLNFIRYLSHFRCVHRGADFAKMRTTTVRKLLPESWGFLCPVHTPDGAPCGLLNHLTAVCEVVTK--FVYTASIPALLCGLGVTPVDAAPCRPYSDCYPVLLDGVMVGWVDKELAPEVADTLRRFKVLRER-RCSSLDGGGPDSHDRKAKPVPRAVPLHHSLQAGEACAEPGAGQRRARWNYGAALHEHCHLRGRGFWWSFHTPGALPSQPAEVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQTPQSPLVRPCMYDHYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEFIDLSEKFKQGD---DSLVFGVKPGDPRVMQKLDNDGLPFIGAKLEFGDPYYGYLNLNTGEGFVVYYKSKENCVVDNIKVCSNDTG-SGKFKCVCVTVRVPRNPTIGDKFASRHGQKGILSRLWPAEDMPFTESGMMPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALEYFGEMLKAAGYNFYGTERLYSGISGMELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDKVTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPLLEKPPPSWS-AMRNRKYNCTVCGRS-------------------------------DSIDTVSVPYVFRYFVAELAAMNIKVKLDVI--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70700-1", "uniprot_id": "RPA2_MOUSE", "id": "P70700-1", "name": "DNA-directed RNA polymerase I subunit RPA2", "aln": "-MDVDGRWRNLPSGPSLKHLTDPSYGIPPEQQK---AALQDLTRAHVDSFNYAALEGLS-----------------HAVQAIPPFEFAFK---DERISLTIVDAVISPPSVPKGTI-CKDLNVYPAECRGRKSTYRGRLTADISWAVN-GVPKGIIKQFLGYVPIMVKSKLCNLYNLPPRVLIEHHEEAEEMGGYFIINGIEKVIRMLIVPRRNFPIAMVRPKWKSRGLGYTQFGVSMRCVREEHSAVNMNLHYVENGTVMLNFIYRKELFFLPLGFALKALVSFSDYQIFQELIKGKEEDSFFRNSVSQMLRIVIEEGCHSQ--KQVLNYLGECFRVKL-SLPDWYPNVEAAEFLLNQCICIHLQSN--TDKFYLLCLMTRKLFALARGECMDDNPDSLVNQEVLSPGQLFLMFLKEKMENWLVSIKIVLDKRAQKANVSINNEN---LMKIFSMGTELTRPFEYLLATGNLRSKTGLGFLQDSGLCVVADKLNFLRYLSHFRCVHRGAAFAKMRTTTVRRLLPESWGFLCPVHTPDGAPCGLLNHLTAVCEVVTK--FVYTASIPALLCGLGVTPVDTAPCRPYSDCYPVLLDGVMVGWVDKDLAPEVADTLRRFKVLREK-RIPPWMEVALIPMTGKPSLYPGLFLFTTPCRLVRPVQNLELGREELIGTMEQLFMNVAIFEDEVFGGISTHQELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQNRSDNKLYRLQTPQSPLVRPCMYDFYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEFIDLSEKFKQGE---DNLVFGVKPGDPRVMQKLDDDGLPFIGAKLEYGDPYYSYLNLNTGEGFVVYYKSKENCVVDNIKVCSNDMG-SGKFKCICITVRIPRNPTIGDKFASRHGQKGILSRLWPAEDMPFTESGMMPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALEYFGEMLKAAGYNFYGTERLYSGISGMELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDKVTNQPLGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHMCVECGSLLSPLLEKPPPSWS-AMRNRKYNCTVCGRS-------------------------------DTIDTVSVPYVFRYFVAELAAMNIKVKLDVI--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H9Y6-1", "uniprot_id": "RPA2_HUMAN", "id": "Q9H9Y6-1", "name": "DNA-directed RNA polymerase I subunit RPA2", "aln": "-MDPGSRWRNLPSGPSLKHLTDPSYGIPREQQK---AALQELTRAHVESFNYAVHEGLG-----------------LAVQAIPPFEFAFK---DERISFTILDAVISPPTVPKGTI-CKEANVYPAECRGRRSTYRGKLTADINWAVN-GISKGIIKQFLGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIRMLIMPRRNFPIAMIRPKWKTRGPGYTQYGVSMHCVREEHSAVNMNLHYLENGTVMLNFIYRKELFFLPLGFALKALVSFSDYQIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCSTQ--KQVLNYLGECFRVKL-NVPDWYPNEQAAEFLFNQCICIHLKSN--TEKFYMLCLMTRKLFALAKGECMEDNPDSLVNQEVLTPGQLFLMFLKEKLEGWLVSIKIAFDKKAQKTSVSMNTDN---LMRIFTMGIDLTKPFEYLFATGNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCVHRGADFAKMRTTTVRRLLPESWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQ--FVYTASIPALLCNLGVTPIDGAPHRSYSECYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREK-RIPPWMEVVLIPMTGKPSLYPGLFLFTTPCRLVRPVQNLALGKEELIGTMEQIFMNVAIFEDEVFAGVTTHQELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQTPQSPLVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEFIDLSEKIKQGD---SSLVFGIKPGDPRVLQKLDDDGLPFIGAKLQYGDPYYSYLNLNTGESFVMYYKSKENCVVDNIKVCSNDTG-SGKFKCVCITMRVPRNPTIGDKFASRHGQKGILSRLWPAEDMPFTESGMVPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALEYFGEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDRVTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPLLEKPPPSWS-AMRNRKYNCTLCSRS-------------------------------DTIDTVSVPYVFRYFVAELAAMNIKVKLDVV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20028-1", "uniprot_id": "RPA2_DROME", "id": "P20028-1", "name": "DNA-directed RNA polymerase I subunit RPA2", "aln": "MLEEMQQMKTIP----VLTNSRPEFKQIPKKLS---RHLANLGGPHVDSFDEMLTVGLDN----------------SAKHMIPNHWLSPA---GEKISMKVESIWIAKPKVPQDVIDVRTREIYPTDSRQLHVSYSGMCSVRLGWSVN-GVQKTPINMDLGEVPIMLRSKACNLGQATPEEMVKHGEHDSEWGGIFVIRGNEKIVRMLIMTRRNHPICVKRSSWKDRGQNFSDLGMLVQTVREDESSLSNVVHYLNNGTAKFMFSHVKRLSYVPVCLILKCLMDYTDEEIYNRLVQGYESDQYYVSCVQAMLREVQNENVYTH--AQCKSFIGNLFRARFPEVPEWQPDDDVTDFILRERVMIHLDTY--EDKFQLIVFMIQKLFQCAQGKYKVENVDSAMMQEVLLPGHLYQKYLSERVESWVSQVRRCLQKKLTSPDALVTSAV---MTQCMRQAGGVGRAIESFLATGNIASRTGLGLMQNSGLVIMAENINRMRYMSHFRAIHRGSYFTTMRTTEARQLLPDAWGFICPVHTPDGTPCGLLNHLTLTCEISMRPDPKLVKAIPKHLIDMGMMPLSNRRYLG-EKLYVVFLDGKHLGHIHQSEAEKIVDELRYGKIFG---TLPQMMEIGFIPFK-KNGQFPGLYIATGPARMMRPVWNLKWKRVEYIGTLEQLYMEIAIDAKEMYPDFTTHLELAKTHFMSNLANLIPMPDYNQSPRNMYQCQMGKQTMGTPCLNWPKQAANKLYRLQTPGTPLFRPVHYDNIQLDDFAMGTNAIVAVISYTGYDMEDAMIINKAAYERGFAYGSIYKTKFLTLDKKSS---------YFARHPHMPELIKHLDTDGLPHPGSKLSYGSPLYCYFDGEVATYKVVKMDEKEDCIVESIRQLGSFDL-SPK-KMVAITLRVPRPATIGDKFASRAGQKGICSQKYPAEDLPFTESGLIPDIVFNPHGFPSRMTIAMMIETMAGKGAAIHGNVYDATPFRFSEENTAIDYFGKMLEAGGYNYYGTERLYSGVDGREMTADIFFGVVHYQRLRHMVFDKWQVRSTGAVEARTHQPIKGRKRGGGVRFGEMERDALISHGAAFLLQDRLFHNSDKTHTLVCHKCGSILAPLQRIVKRNETGGLSSQPDTCRLCGDN-------------------------------SSVSMIEIPFSFKYLVTELSSVNINARFKLNEI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22138-1", "uniprot_id": "RPA2_YEAST", "id": "P22138-1", "name": "DNA-directed RNA polymerase I subunit RPA135", "aln": "-MSKVIKPPGQARTADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFN-ALTEGPDGGLLNLGVKDIGEKVIFDGKPLNSEDEISNSGYLGNKLSVSVEQVSIAKPMSNDGVSSAVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQ-SDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQ--QSDVSRIPSILYSLGVAPASHTFAAG-PSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPS-TRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALNRNRGDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKKLLTKSEDGEKIFIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : . . . : . * : .*: **: * . . . :: .:::*..: . *: * ... ::**::.* :* * : *:** * : * :*:*::*: *:* : .* :::* *. .* ** *::.* **::****: ***.*:.: *..: ** .::. *: :: ** :.:: . :**:::* . : * *. :*: : **.* :* :*:: :: . .*.: . :. :** . :. : * .::*: **. : *: .: :. : :: . : :** . :** :: :* :**: . *: :* *: **** * *: *.*::: :: .: . . . : : :: :::***: *::**.: * ** ::*:::* *::**** :***: *: ::** .*:***::***:******** ****:**:: *.: : . ** * .:*: * . . * :** :* : :. . :.* ** *: . . . * : .. : : . . . :**: *:.*.****************** * : .:: ******** :*:.:. ** :*::. * **:***********:****:**:: ****.:*::**:: : * : . *. . . :::** ****. *: :. *.* *:: : ...* . ::.:. .. : : :.:. *: * . *****:** ****: *: :*: *:**:*:*: ***::***.*******.*::*::***..*:** *:**: *.*:::. :***: * .***::*.* :*** * *: ***:.***:******** **:***:**. : * **: **: **:*.********:.**::***:***:: ** : : :* :***:*:. . : : . . . . . : :*: ::*: :**:::.*. : .: ", "identical_positions": 334, "similar_positions": 354, "identity": "27.6%" }, { "cls_id": "homologset.agr.SGD:S000006215", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JVD2-1", "uniprot_id": "A0A0G2JVD2_RAT", "id": "A0A0G2JVD2-1", "name": "Mitochondrial adenyl nucleotide antiporter SLC25A23", "aln": "-----------------------------------------------------------------------MRGGSGDAERRQRWGR--------------------------------LFEELDSN--KDGRVDVHELRQGLARLGRGDPDRAQQGISSDWDSDADGGLSLEEFTQYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRALGFSISMEQAEKILHSMDRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSKQEKLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKSNR-LNILGGLRNMVQEGGLLSLWRGNGINVLKIAPESAIKFMAYEQIKRAICGQQET-----LHVQERFVAGSLAGATAQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILE--------------REGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNRWLQQYSHESANPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGG-----------------PQVSMVGLLRHILSQEGVWGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B8ZHC9-1", "uniprot_id": "S2541_RAT", "id": "B8ZHC9-1", "name": "Calcium-independent mitochondrial carrier protein SCaMC-3L", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGVHLEVLDTGEQLMVPGDVLEEENK-GTLWKFLLSGAMAGAVSRTGTAPLDRARVYMQVYSSKSNF-RHLLSGLRSLVQEGGIRSLWRGNGINVLKIAPEYAIKFSVFEQSRNFFYGVHTS-----PSFQERVVAGSLAVAISQTLINPMEVLKTRLTLRFTGQYKGLLDCARQILE--------------RDGTRALYRGYLPNMLGIIPYACTDLAVYELLRCLWQKS-GRDMKDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEG------------------SNPTMLGVFKRILNQQGWPGLYRGMTPTLLKVLPAGGISYLVYEAMKKTLGVQVLSR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K3P6-1", "uniprot_id": "SCMC2_RAT", "id": "Q8K3P6-1", "name": "Mitochondrial adenyl nucleotide antiporter SLC25A25", "aln": "-----------------------------------------------------------------------MLCLCLYVPIAGEAQT--------------------------------EFQYFESKGLPTELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNN-MCIIGGFTQMIREGGAKSLWRGNGINVLKIAPESAIKFMAYEQMKRLVGSDQET-----LRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCAKRILA--------------KEGVAAFYKGYIPNMLGIIPYAGIDLAVYETLKNTWLQRYAVNSADPGVFVLLACGTISSTCGQLASYPLALVRTRMQAQASIEGA-----------------PEVTMSSLFKQILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F7EXY7-1", "uniprot_id": "F7EXY7_RAT", "id": "F7EXY7-1", "name": "Mitochondrial adenyl nucleotide antiporter SLC25A24", "aln": "-----------------------------------------------------------------------MLRWLRAFVLPTAVCQDA----------------------EPPTRYETLFRALDRNG--DGVVDIGELQQGLQSLGIPLGQAAEEKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEPFEIVQSLQMLGLNISEKQAELILQSIDSDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGVAGAVSRTSTAPLDRLKVMMQVHGSKS---MNIFGGFRQMVKEGGIRSLWRGNGINVIKIAPETAVKFWAYEQYKKLLTEEGQK-----LGTSERFISGSMAGATAQTFIYPMEVLKTRLAVAKTGQYSGIYGCAKKILK--------------HEGFRAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVVVLLGCGALSSTCGQLASYPLALVRTRMQAQATTEGA-----------------PQLSMVGLFQRIVSKEGVSGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVAQK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZTW5-1", "uniprot_id": "D3ZTW5_RAT", "id": "D3ZTW5-1", "name": "Mitochondrial adenyl nucleotide antiporter SLC25A24", "aln": "-----------------------------------------------------------------------MLSWLQDVLWPSKAPKSD----------------------YDDLAFEILFEDLDRNG--DGVVDITELRDGLEHWNSSFGIDPEKKILKSADSNADSGLDFGEFVKYLQDHEKKMKLAFKSLDKNADGVIDASEVVAAMKSLGIHISLAQANDILKSMDADGSMTVDWDEWRDYFFFHPAKNVTDIIRFWKHSTIIDIGESVSIPDEFTEQEKKSGEWWKRLVAAGIASAITRTCTAPLDRLKVMIQVQSSKMSK-LRLVHVFKQMVKEGGLFSLWRGNGVNIFKITPETAIKIGAYEQYKKLLSFEDAN-----LGFLQRFTAGSMAGITSQTCVYPLEVIKTRLILGRTGEFSGIIDCGRKLLR--------------REGIQAFSRGYVPNLLSIVPYAGLDLTIFELLKNYWLEHYAESSVNPGLAIVLGCSTLSHTFGQLASFPLNLVRTRMQAAMLEN-------------------ETIPMMQLIQEIYTKEGKKGFFRGLTPNVLKLLPAVGIGCVAHELVNLLFGLT----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0E8F2-1", "uniprot_id": "SCMC_DROME", "id": "Q0E8F2-1", "name": "Mitochondrial adenyl nucleotide antiporter SCaMC", "aln": "MVRKQVGIENSASLAVSKQQDQKEQDYKPEDQKQQHIDIDLTPDPASNFNFAQQAQANYSARTLAASYEHGQNLGLQHAHLATSSTTNTPLAYDLHEVASSGSILPTEIPIEDEERLERIFNKLDRDG--DGRIDIHDLSAALHEFGLS--SVYAEKFLQQSDKDQSGNVGFAEFLHYVREHEKNLVLQFSHLDKNRDGKVDLEELISAFKDLGLDIDMDEARNLLTRMDKDGSLNISFNEWRDFMLLAPSTDIHDLIKFWRHSTYLDIGEDMNVPDDFTQKEMQTGLWWRHLVAGGIAGAVSRTCTAPLDRIKVYLQVQTQRMG----ISECMHIMLNEGGSRSMWRGNGINVLKIAPETAFKFAAYEQMKRLIRGDDGSR---QMSIVERFYAGAAAGGISQTIIYPMEVLKTRLALRRTGQYAGIADAAVKIYK--------------QEGVRSFYRGYVPNILGILPYAGIDLAVYETLKRRYIANHDNNE-QPSFLVLLACGSTSSTLGQLCSYPLALVRTRLQAQAAETIANQKRKTQIPLKSSDAHSGEETMTGLFRKIVRQEGLTGLYRGITPNFLKVLPAVSISYVVYEYTSRALGIKMS--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12251-1", "uniprot_id": "YP011_YEAST", "id": "Q12251-1", "name": "Uncharacterized mitochondrial carrier YPR011C", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEVLTVLEQPNSIKDFLKQDSN-----IAFLAGGVAGAVSRTVVSPFERVKILLQVQSSTTSYNRGIFSSIRQVYHEEGTKGLFRGNGLNCIRIFPYSAVQFVVYEACKKKLFHVNGNNGQEQLTNTQRLFSGALCGGCSVVATYPLDLIKTRLSIQTANLSSLNRSKAKSISKPPGIWQLLSETYRLEGGLRGLYRGVWPTSLGVVPYVALNFAVYEQLREFGVNSSDAQPSWKSNLYKLTIGAISGGVAQTITYPFDLLRRRFQVLAMGGNELG--------------FRYTSVWDALVTIGRAEGVSGYYKGLAANLFKVVPSTAVSWLVYEVVCDSVRNW----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :. .: :::.. *.*::** .:*::* :: :** . : : : .* * .::****:* ::* * *.:: .:* :. . . :*. :*: . : *::::***: : :. . . : . * .: :* *. *.::**. :::::* *: . . * : * .* ::*: *:* *:*. .: : * :* * ::*::...:*::*: .:. :.:* . ", "identical_positions": 48, "similar_positions": 105, "identity": "7.86%" }, { "cls_id": "homologset.agr.SGD:S000006220", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55135-1", "uniprot_id": "IF6_MOUSE", "id": "O55135-1", "name": "Eukaryotic translation initiation factor 6", "aln": "MAVRASFENNCEVGCFAKLTNAYCLVAIGGSENFYSVFEGELSDAIPVVHASIAGCRIIGR--MCVGNRHGLLVPNNTTDQELQHIRNSLPDSVQIRRVEERLSALGNVTTCNDYVALVHPDLDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSLLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDSLT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3KRD8-1", "uniprot_id": "IF6_RAT", "id": "Q3KRD8-1", "name": "Eukaryotic translation initiation factor 6", "aln": "MAVRASFENNCEVGCFAKLTNTYCLVAIGGSENFYSVFEGELSDTIPVVHASIAGCRIIGR--MCVGNRHGLLVPNNTTDQELQHIRNSLPDSVQIRRVEERLSALGNVTTCNDYVALVHPDLDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSLLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDSLT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AC66-1", "uniprot_id": "A0A8I6AC66_RAT", "id": "A0A8I6AC66-1", "name": "Eukaryotic translation initiation factor 6", "aln": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVL--TVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56537-1", "uniprot_id": "IF6_HUMAN", "id": "P56537-1", "name": "Eukaryotic translation initiation factor 6", "aln": "MAVRASFENNCEIGCFAKLTNTYCLVAIGGSENFYSVFEGELSDTIPVVHASIAGCRIIGR--MCVGNRHGLLVPNNTTDQELQHIRNSLPDTVQIRRVEERLSALGNVTTCNDYVALVHPDLDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSLLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAQPSTIATSMRDSLIDSLT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZM19-1", "uniprot_id": "IF6_DANRE", "id": "Q6ZM19-1", "name": "Eukaryotic translation initiation factor 6", "aln": "MAVRASFEKNNEIGCFAKLTNTYCLVAIGGSENFYSVFEGELSETMPVIHASIAGCRIIGR--MCVGNRHGLLVPNNTTDQELQHIRNCLPDSVRIQRVEERLSALGNVIACNDYVALVHPDLDRETEEILADTLKVEVFRQTVAEQVLVGSYCAFSNQGGLVHAKTSIEDQDELSSLLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVIESVFRLSETQPSAIATTMRDSLIDSLT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P56538-1", "uniprot_id": "IF6_DROME", "id": "P56538-1", "name": "Eukaryotic translation initiation factor 6", "aln": "MALRVQFENNDDIGVFTKLTNTYCLVAIGGSETFYSAFEAELGDTIPVVHANVGGCRIIGR--LTVGNRNGLLVPNSTTDEELQHLRNSLPDAVKIYRVEERLSALGNVIACNDYVALVHPDLDKETEEIIADVLKVEVFRQTIADNSLVGSYAVLSNQGGMVHPKTSIQDQDELSSLLQVPLVAGTVNRGSEVLAAGMVVNDWLSFVGMNTTATEISVIESVFKLNQAQPATVTTKLRAALIEDMS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12522-1", "uniprot_id": "IF6_YEAST", "id": "Q12522-1", "name": "Eukaryotic translation initiation factor 6", "aln": "MATRTQFENSNEIGVFSKLTNTYCLVAVGGSENFYSAFEAELGDAIPIVHTTIAGTRIIGR--MTAGNRRGLLVPTQTTDQELQHLRNSLPDSVKIQRVEERLSALGNVICCNDYVALVHPDIDRETEELISDVLGVEVFRQTISGNILVGSYCSLSNQGGLVHPQTSVQDQEELSSLLQVPLVAGTVNRGSSVVGAGMVVNDYLAVTGLDTTAPELSVIESIFRLQDAQPESISGNLRDTLIETYS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. *..**:. ::. *::***:*.***:****.***.**.**.:::*::*:.:.. ***** *. * *. ***:****:::.* *:*:* **** ****.** ***********:*:****:::..* ***: *:: : *****. :*****:*:.:**::**:**** **************.*:.*******: :. *::**:.*:**:**:*:*.:::* ::: .:* :**: :", "identical_positions": 130, "similar_positions": 83, "identity": "52.63%" }, { "cls_id": "homologset.agr.SGD:S000006221", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08326-1", "uniprot_id": "MSS4_RAT", "id": "Q08326-1", "name": "Guanine nucleotide exchange factor MSS4", "aln": "--MEPCELQ---NELVSAEGRNRKAVLCQRCGSRVLQPGTALFSRRQ-----LFLPSMRKKPDLVDGSNPDGDVLEEHWLVNDMFIFENVGFTKDVGNVKFLVCADCEIGPIGWHC-------LDDKNSFYVALERVSHE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6GKW6-1", "uniprot_id": "A0A8I6GKW6_RAT", "id": "A0A8I6GKW6-1", "name": "Guanine nucleotide exchange factor MSS4", "aln": "--MEPCELQ---NELVSAEGRNRKAVLCQRCGSRVLQPGTALFSRRQ-----LFLPSMRKKPDLVDGSNPDGDLLEKHWLVNDMFIFENVGFTKDVGNVKFLVCADCEIGPIGWHC-------LDDKNSFYVALERVSHE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91X96-1", "uniprot_id": "MSS4_MOUSE", "id": "Q91X96-1", "name": "Guanine nucleotide exchange factor MSS4", "aln": "--MEPCELQ---NELVSAEGRNRKAVLCQRCGSRVLQPGTALFSRRQ-----LFLPSMRKKPDLADGSNPDGDLLQEHWLVNDMFTFENVGFTKDVGNIKFLVCADCEIGPIGWHC-------LDDKNSFYVALERVSHE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47224-1", "uniprot_id": "MSS4_HUMAN", "id": "P47224-1", "name": "Guanine nucleotide exchange factor MSS4", "aln": "--MEPAEQP---SELVSAEGRNRKAVLCQRCGSRVLQPGTALFSRRQ-----LFLPSMRKKPALSDGSNPDGDLLQEHWLVEDMFIFENVGFTKDVGNIKFLVCADCEIGPIGWHC-------LDDKNSFYVALERVSHE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLP3-1", "uniprot_id": "MSS4_DROME", "id": "Q9VLP3-1", "name": "Guanine nucleotide exchange factor MSS4 homolog", "aln": "-MTEEADFS---EQIT--DGKNKSNVRCQFCNCLMLKAQEGTYNQEE-----VDVPLMTQKQDRTADS-LNSEPLKDFWLVKDMMTFENIGFSNTVDGRKFLVCADCERGPVGYHD-------LSTR-HCYLALKRVVHKDT-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32601-1", "uniprot_id": "MSS4_YEAST", "id": "P32601-1", "name": "Protein DSS4", "aln": "MSKATCSFEGCHSAVITINDDNIINLPEQVHSEFKLLENRTMRDATPSESNFLVVPDVWDFDNVGVSREIPSSILGDLSDKSDFVFEYGNSSWKIKKCLKYLICADCDKGPIGIICKVQDQTKNEERVLHLLSLRSLQIMGRN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . : :. * : * . * . : :* : . . .. * . .*:. . . : *:*:****: **:* . : ::*. : ", "identical_positions": 16, "similar_positions": 33, "identity": "11.19%" }, { "cls_id": "homologset.agr.SGD:S000006222", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0JMK9-1", "uniprot_id": "CAF1A_DANRE", "id": "A0JMK9-1", "name": "Chromatin assembly factor 1 subunit A", "aln": "----MVVVMLAAEEPLASTPRRDMDCVGKANTNKKLVQARLPFKRLNP-----------------------------------------------EPKECNE---------------------------------------------------------------PKRTKG-------------------------------------PVAPKCSEPSD---------------------QENDQDSSSISHHGPALVNGRG--------PLDCFMSRRKRSPLRSAP-----EATIDLTEDSNDSAKQQPAPPIAATCPLSEEKTKTSEGTTEPTIP----------------LTEEETEKDEAEDVDALPLLDITQDSDTEEEEEEEEEEEEQQQEAEVSHGNESVLSTG---------------------------STSSASVIASSPEPSKSAPTTPASTSRINAANKVKRRSLKSVQ-------------------EQEEKQRQRDEKERLKQEAKAAKEKKKEEARKMKEEK---EREKKEKKEKDEKERREKKERDEKEKADKLKAKEEQRQMKIEAKLEEKRKKEEEKRLKEEKDRIKAEK----------------AEITRFLQKPKTQLAPKTLASACGKFAPFEIKAHMSLAP---LTRVQCEDSVLEDLDRYLAQPDSTLNG-----LKDWTGHKPR----------SSGPTRPRHSAQGDCVVITESQKADDG-------------------PDRSRYGRMKLLHFHDNYRPAYWGTWSKKSTHISPRCPLRLDKDLLDYEVDSDEEWEEEEPGESLSHSEGDDDDEAGED-DDDDDGFFVPHGYLSEGEGALED---EEGGDPEKQKVRQRMKAREWENELMSKGKVKVLEAVVRGCFWEGEKP---------LPDFLQPYAVCMLEPLSKDEASTPEQDASRQQR------NEKLLTMLLPLLHGNVNSNKVIITEFLEFCRQQTSSPTES--------------LLNTTESIPPRIHVRRIIKENAVYEKRSTFKRCCWYVHADVLARYSQEALPVPCQWSYLTSGANVTRDEHSGSQGNSPTTNSSTTPSNKRKSASSHSITKYMKKCGESEQTEAMETDGFQADTEDDEDDDCIIIGEQSGSSEQDINTSLPQTDRETEPMDTSASETAALALPCPTPATA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3D1-1", "uniprot_id": "Q9W3D1_DROME", "id": "Q9W3D1-1", "name": "", "aln": "MHAGVVKTPLSGRKKDAAVPAKSAEKT--ASGGKKFVQTRLPFKLLTPGGGAVPTSSSSSSSPATIGSGPVTVILDEDDPAPRKRKLSYDDESPSEGTGCSTGQLRRSTSKENLDLASSIATKKVKTTDSVVEDVIELDEDEADKEIEDQDQLVEAKSSKEVKLKPKKSEGKKGSPAPIQIKLPLVNKRSKRRKSLKKSEEPLETSTADVAKGDSESSDDIEIIAEELNPQKRQKVQTPREKSPENSSTSGKHTEEVMQKNGKDSKKQEESMKAVKESKKEEPKTAEQNKKNDQATIDLFMGKKMETNKKDKPEVKTTAKDNKKDPLIAEDSKPKEVPKKETSKTGGKGKKEGAKPAEKSKKEEKEDSTTKSKKEKADSPANNQKEQQIGVKKKTSEPEDASNSHKSVTAKKDSKKDEASTQVKSDNESPEAAEISMILSTSEANSSSSEHEMDADTDTAATDRPSAQKETRLNRKSLPEVTGAPKGLTPKQQRLMEQRKKAREEKEQKLAEERRLKQQDKEHREQQKKQERDEKEQQRKLERDQKEQQRKMEKEEKERKRQAEVDSKNEEKRKRNEAKEEVQRKKDEERRKKEQEREEAEQKKKRAAESFSKFFVPKQPKCGSGSNNTSYLEHEQSSCDSSKASSQTLAFRPFQIKDDMLLAP---IVRNSLGQEQRSQLDGLFRHRDEEADDEEEEEEQDIVRRKPPNRANLYLSELSSGRRKPLKMQRDVKLQRRTKDEEDDDDVQVIDYLSPAGLPIEVEQPKQLTRMKAKYLHFADNRRPPYYGTWRKKSSSISARRPLAQDKVLFDYEVDSDCEWEEEEPGESLSASEDEKEKESEEESEEEYNEWYVPHGHLSDEELQNDGDGMEDGHTREAQKAKLQVLQQEFAQEMKK--QTKKIKARLLGPVWLDENGNKSELFPAIFAHTIDMYACWQVEPLSLEPPPEPERQDQTPEQPVPLQLDDRLMQQLVRLTHGNRNSKTFLINEYLEYLKTQATAEANQTTLPSKAVLREKFDELASWKTVELSTPEAAAASANSAKKGRKPKKRLCWVVASDMLEKFQLPDLQLQNQWNYTLT-PKVSDGPDAAQQEQSPPADAVPAASPASNQTTNSAPTTPISGQTQAGQGVKKRATLIMSVPRDQP--------IPSATKNKLISQFLQRQSDASKPKEKMQEKPPPIVFDDVVMLSD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12495-1", "uniprot_id": "CAF1A_YEAST", "id": "Q12495-1", "name": "Chromatin assembly factor 1 subunit A", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEQHLKSIPLQDDT------------KKKGILSFFQNTTTVKSNKFLTKEKDVITLDDP----------------------------KEDVSGPMIETVKQETMKSINKECADEMKTTPKKANAEDKLLCYK------------------------------------NSPIQSTKYDRNTNKQVPNGNIIAIETKSRSS------------------------------SPCSKRELSSSKKEEAKREKELKKQQRAEEKHRKELLRQEEKKKKELKVEEERQRRAELKKQKEEEKRRKEEARLEAKRRKEEERLKKEEEIRLKEEAKERAQSR-----------------IGNFFKKLSDSNTPVVEKSDYEKFFLPFYAKDGVRVSNKWKLTKVELEGSKRKIDDELLNSKDKTSSDD----LLNWLQSRRLP-----------RGHKIKRKAVDVLQQMPLKEKTDDEL------------------QSLLAQVPHKYIKFYENVRPPFIGTYS-MDFTLPPNDPFSTKGTGFNYDYDSDVEWVNEEEEGEVDNLESGEEEEEEEDDEDVPSEGEFDGFLDSEENSDLDG---------------LPCAKRKFVGPLIP-----------------------------------TICLKSNFENLSEEN------------------------------------------KRYLQQLKAEVIIETDG-----------------------------PIDPFKEPKTSSLPSKRSNSDLQAQTASQSQSPEKKQKAMITDPMDLLRLFDGVQDSTFSLGTVTEIAQKNLPQYNKQTIKNTIKEYAIR--------------------------------SSGKGDLPRKWVIKDAQNWENLRANANMPTPSL---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * * . : : . : :. .::. : . *:: .. . : : .. .:: :: : : : : .: ::. : . . .. . : .: . . : . *:: * :* :*:: . *..: .:::*:::. :*.:::: . : :. :: : *.: . * :*. :*:*: * : * .. . . : : .:. :. * ** * : :: :.: . . . * : *. .. : : : : . .:: ** . * ::* :* **.: **: . :... *: . ::*: *** ** :** .:. *. .:.* *: :: . . *: : :. ::: : .* ** : ..:*: : :. :: : . ** : :: : . . .: . . . .. :: :. : . *. . . : : : . ... ", "identical_positions": 52, "similar_positions": 203, "identity": "4.34%" }, { "cls_id": "homologset.agr.SGD:S000006223", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49717-1", "uniprot_id": "MCM4_MOUSE", "id": "P49717-1", "name": "DNA replication licensing factor MCM4", "aln": "MSSPASTPSR--RSSRRGRVTPTQSL---------------------RSEESRSSPNRRRRGEDS-STGELLPMPTSPGAD---LQSPPAQNALFSSPPQMHSLAIPLDFDVSSPLTYGTPSSR-VEGTPRSGVRGTPVRQRPDLGSARKGLQVDLQS---------DGAAAEDIVPSEQSLGQKLVIWGTDVNVATCKENFQRFLQ----CFTDPLAKEEENVG-IDITQPLYMQQLGEINITGEPFLNVNCEHIKSFSK--NLYRQLISYPQEVIPTFDMAVNEIFFDRYPDSILEHQI--------QVRPFNALKTKSMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEIDRGRIAEPCSCV--HCHTTHSMALIHNRSFFSDKQMIKLQESPEDMPAGQTPHTIVLFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFS---------------EKRVKLLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVSLYYQ--SEEQVEEEFLDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVNMRKIG----SSRGMVSAYPRQLESLIRLAEAHAKVRFSNKVEAIDVEEAKRLHREALKQSATDPRTGIVDISILTTGMSATSRKRKEELAEALRKLILSKGKTPALKYQQLFEDIRGQSDTAITKDMFEEALRALADDDFLTVTGK-TVRLL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V681-1", "uniprot_id": "G3V681_RAT", "id": "G3V681-1", "name": "DNA replication licensing factor MCM4", "aln": "MSSPASTPSR--RSSRRGRVTPTQSL---------------------RSEESRSSPSGRRRGEDS-STGELLPMPTSPGAD---LQSPAAQNALFSSPPQMHSSAIPLEFDVSSPLTYGTPSSR-VEGTPRSGVRGTPMRQRPDLGSARKGLQVDLQS---------DGAAAEDTVASEQSLGQKLVIWGTDVNVATCKEHFQRFLQ----CFTDPLAKEEENVG-IDITQPLYMQRLGEINITGEPFLNVNCEHIKSFGK--NLYRQLISYPQEVIPTFDMAVNEIFFDRYPDSILEHQI--------QVRPFNALKTKSMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRGRIAEPCTCV--HCHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVVLFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFS---------------EKRVKLLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVSLYYQ--SEEQVEQEFLDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVNMRKIG----SSRGMVSAYPRQLESLIRLAEAHAKVRFSDKVEAIDVEEAKRLHREALKQSATDPRTGIVDISILTTGMSATSRKRKEELAEALRKLILSKGKTPALKYQQLFEDIRGQSDTAITKDMFEEALRALADDDFLTVTGK-TVRLL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P33991-1", "uniprot_id": "MCM4_HUMAN", "id": "P33991-1", "name": "DNA replication licensing factor MCM4", "aln": "MSSPASTPSR--RGSRRGRATPAQTP---------------------RSEDARSSPSQRRRGEDSTSTGELQPMPTSPGVD---LQSPAAQDVLFSSPPQMHSSAIPLDFDVSSPLTYGTPSSR-VEGTPRSGVRGTPVRQRPDLGSAQKGLQVDLQS---------DGAAAEDIVASEQSLGQKLVIWGTDVNVAACKENFQRFLQ----RFIDPLAKEEENVG-IDITEPLYMQRLGEINVIGEPFLNVNCEHIKSFDK--NLYRQLISYPQEVIPTFDMAVNEIFFDRYPDSILEHQI--------QVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRGRIAEPSVCG--RCHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFS---------------EKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQ--SEEQAEEELLDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVDMRKIG----SSRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREALKQSATDPRTGIVDISILTTGMSATSRKRKEELAEALKKLILSKGKTPALKYQQLFEDIRGQSDIAITKDMFEEALRALADDDFLTVTGK-TVRLL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q26454-1", "uniprot_id": "MCM4_DROME", "id": "Q26454-1", "name": "DNA replication licensing factor MCM4", "aln": "MSSPARSPSVGGATPKQGARTPTRGI---------------------ASQDVET-PMRMGPGRAVRPSDNISLPPTSPG-----------NISLPATSPARGLGANMSEIDLSSPLNYGTPSSMGSIRTPRSGIRGTPLRARPDIRTDKRIRQVAIGGGSGLEPIPEKGSETTDPVS-ESSQAPQLVVWGTNVVVSQCKSKFKSFIM----RFIDPSAEQDEISENIDVNQPLYLQKLEEIHTLEEPYLNLNCAHLKTFDQ--DLYRQLICYPQEVIPGFDMAINEMFFERYPAALLEHQI--------QVRPFNADKTRNMRSLNPEDMDQLISISGMVIRSSNVIPEMREAFFSCNICSFSTTVEVDRGRINQPTLCT--NCNTNHCFRLIHNRSEFTDKQLVKLQESPDDMAAGQTPHNVLLYAHNDLVDKVQPGDRVTVTGIYRATPLKTGGLSSSVKSVYKTHVDVVHFRKVDNKRLY-EDEEGKDHIFP---------------PERVELLQLLAKKPDIYDRLARAIAPSIYENDDIKKGILLQLFGGTKKKHATLGRQNFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSAVGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPAESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLYYV--TRHEEEDTMFDMSVLRDYIAYAREHLSPTLSDEAQQRLIQAYVDMRKVG----AGRGQISAYPRQLESLIRLSEAHAKVRLSNQVELLDVEEAWRLHREALKQSATDPLSGKIDVGILTTGLSTAARKKRADLVAAIKENLKKKGKVLTVPYQKLFSDIKEGSQIMITREQFEDALKEVQDEGAIVVMGKNTIRIC------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P30665-1", "uniprot_id": "MCM4_YEAST", "id": "P30665-1", "name": "DNA replication licensing factor MCM4", "aln": "MSQQSSSPTKEDNNSSSPVVPNPDSVPPQLSSPALFYSSSSSQGDIYGRNNSQNLSQGEGNIRAAIGSSPLNFPSSSQRQNSDVFQSQGRQGRIRSSASASGRSRYHSDLRSDRALPTSS-SSLGRNGQNRVHMRRNDIHTS-DLSSPRRIVDFDTRSG------VNTLDTSSSSAPPSEASEPLRIIWGTNVSIQECTTNFRNFLMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSNLNLDARNLLAYKQTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKFYKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRGVIQEPARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGTFRSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTSTIEQELMQNKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGR--YRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNLVQTGKSVIQRKLQEDLSREIMNVLKDQASD-SMSFNELIKQINEHSQDRVESSDIQEALSRLQQEDKVIVLGEGVRRSVRLNNRV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. : :*: . . . :: .. . . :. : .:* : : ::.. :: . .* .: ** * :* . :: *: : :: :. . : . .. ..: ::***:* : *. :*: *: * . :.:* : *:::* *:. . **::. :: :: : :**:**: ******. :* :::: :.. *:::: :***:*. . :.**.***:*:*:**.:.*:*:*:: :**:*: ***.*::* .: **:*** * :* * *: :.: *****. *:***::****:*: :. *****.: * .:::***. :.***: *** :*: *::.. :**:***::**:* :*.. *** . ::.:: : : :: :: : *:*. ** ::****** :*:************.* .: ** :*.:*::******.*****:****.::.**. ****:**********: :* :*:****::*****:*.*:*********.:**************:******** ****:*:**:*** *::* . :*::** .*******::*:** ** *:.** **. ** ... :: .: : .* **:**:. : * ::: *. *:.***.***:* :.. ::* .*****:***:*****:::.: ** **:** ** *.*:*: **** :* :*:.:: ** *. ** : :* : : : .:.. :: :::*:.:*. *: : . :::** : ::. : * *: . * ", "identical_positions": 309, "similar_positions": 293, "identity": "32.73%" }, { "cls_id": "homologset.agr.SGD:S000006224", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CPQ8-1", "uniprot_id": "ATP5L_MOUSE", "id": "Q9CPQ8-1", "name": "ATP synthase F(0) complex subunit g, mitochondrial", "aln": "----MAKFIRNFAEKAPSMVAAAVTYSKP-RLATFWHYAKVELVPPTPAEIPTAIQSVKKIIQSAKT---GSFK-----HLTVKEAVLNGLVATEVWMWFYIGEIIGKRGIVGYDV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "J3QNM7-1", "uniprot_id": "J3QNM7_MOUSE", "id": "J3QNM7-1", "name": "ATP synthase F(0) complex subunit g, mitochondrial", "aln": "----MAKFIHNFSEKALSMVAAAVTYLKP-QLVTFWHYAKVELVPPTPGEIPTAIQNVKKIIQSAKT---GSFK-----HLTVKEAVLNGLVATEVLMWFYIGEIMGKRGIVGYDV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PDU7-1", "uniprot_id": "ATP5L_RAT", "id": "Q6PDU7-1", "name": "ATP synthase F(0) complex subunit g, mitochondrial", "aln": "----MAKFIRNLADKAPSMVAAAVTYSKP-RLATFWHYARVELVPPTLGEIPTAIQSMKSIIHSAQT---GNFK-----HLTVKEAVLNGLVATEVWMWFYIGEIIGKRGIVGYDV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75964-1", "uniprot_id": "ATP5L_HUMAN", "id": "O75964-1", "name": "ATP synthase F(0) complex subunit g, mitochondrial", "aln": "----MAQFVRNLVEKTPALVNAAVTYSKP-RLATFWYYAKVELVPPTPAEIPRAIQSLKKIVNSAQT---GSFK-----QLTVKEAVLNGLVATEVLMWFYVGEIIGKRGIIGYDV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7Z4Y8-1", "uniprot_id": "AT5L2_HUMAN", "id": "Q7Z4Y8-1", "name": "ATP synthase subunit g 2, mitochondrial", "aln": "----MAPFVRNLVEKTPALVNAAVTYLKP-RLAAFWYYTTVELVPPTPAEIPRAIQSLKKIVSSAQT---GSFK-----QLTVKEALLNGLVATEVSTWFYVREITGKRGIIG----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKM3-1", "uniprot_id": "Q9VKM3_DROME", "id": "Q9VKM3-1", "name": "ATP synthase subunit g", "aln": "--------MASLATKGSGLVNRLLTQARP-QLDVFLKYAKVELTPPTPADIPAIRQGLGNIIKGAKT---GAYK-----NLTVREAWLNTLVTAEVIFWFYIGECIGKRHIVGYNV-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLY0-1", "uniprot_id": "Q9VLY0_DROME", "id": "Q9VLY0-1", "name": "ATP synthase subunit g", "aln": "--------MSQLIAKAKTLVNKMIVAARP-QLDEFWKYAKVELSPPLPADFQKLKQTAESAKLASKKDMKGQLKKSGLSQVTVAEAWLNVLVTVEVITWFYMGEVIGRRHLVGYKV-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12233-1", "uniprot_id": "ATPN_YEAST", "id": "Q12233-1", "name": "ATP synthase subunit g, mitochondrial", "aln": "MLSRIQNYTSGLVSKANLLSSKALYYGKVGAEISKQIYLKEGLQPPTVAQFKSVYSNLYKQSLNFALKPTEVLS--CLKNIQKNELLKYGAYGIQLIGFYSVGEIIGRRKLVGYKHH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : : : * * ** .:: . . . :: * :: :: : * *:* ::* ", "identical_positions": 10, "similar_positions": 20, "identity": "8.55%" }, { "cls_id": "homologset.agr.SGD:S000006225", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LZW6-1", "uniprot_id": "S2513_RAT", "id": "F1LZW6-1", "name": "Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial", "aln": "--------------------------------MAAAKVALTKRADPAELKAIFLKYASIEKNGEFFMSPHDFVTRYLN-----------IFGESQPNPKTVELLSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVRQVFG------------QTTIHQHIPFNWDSEFVQLHFGKERKRHLTYAEFT---------------QFLLEIQLEHAKQAFVQRDNAKTGKVTAIDFRDIMVTIRPHVLTPFVEECLVA------------------------------AAGGTRSHQVSFSYFNGFNSLLNNMELIRKIYSTLAGSRKDVEVTKEEFALAAQKFGQVT--------------PMEVDILFQLADLYEPRGRMTLADIERIAPLEEG-MLPFNLAEAQRQQ--------------------------------------------------------------------------------------KASGDAARPFLLQLAESAYRFGLGSIAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLLAEIFAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSA--------------------------LSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASF-------ANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARA-GQTTYSGVTDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWFYVDFGGVKPVGSEL----VPKSRIT--LPAPNPDHVGGYKLAVATFAGIENKFGLYLPLFKP---SASTSKVTAVGS----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXX4-1", "uniprot_id": "S2513_MOUSE", "id": "Q9QXX4-1", "name": "Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial", "aln": "--------------------------------MAAAKVALTKRADPAELKAIFLKYASIEKNGEFFMSPHDFVTRYLN-----------IFGESQPNPKTVELLSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQIFG------------QTTIHQHIPFNWDSEFVQLHFGKERKRHLTYAEFT---------------QFLLEIQLEHAKQAFVQRDNAKTGKVSAIDFRDIMVTIRPHVLTPFVEECLVA------------------------------AAGGTRSHQVSFSYFNGFNSLLNNMELIRKIYSTLAGNRKDVEVTKEEFALAAQKFGQVT--------------PMEVDILFQLADLYEPRGRMTLADIERIAPLEEG-MLPFNLAEAQRQQ--------------------------------------------------------------------------------------KASGDAARPFLLQLAESAYRFGLGSIAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLLAEIFAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSA--------------------------LSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASF-------ANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARA-GQTTYNGVTDCFRKILREEGPKALWKGVAARVFRSSPQFGVTLLTYELLQRWFYVDFGGVKPVGSEP----VPKSRIT--LPAPNPDHVGGYKLAVATFAGIENKFGLYLPLFKP---SASTSKVTAGDS----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJS0-1", "uniprot_id": "S2513_HUMAN", "id": "Q9UJS0-1", "name": "Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial", "aln": "--------------------------------MAAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLN-----------IFGESQPNPKTVELLSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQVFG------------QTTIHQHIPFNWDSEFVQLHFGKERKRHLTYAEFT---------------QFLLEIQLEHAKQAFVQRDNARTGRVTAIDFRDIMVTIRPHVLTPFVEECLVA------------------------------AAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTLAGTRKDVEVTKEEFVLAAQKFGQVT--------------PMEVDILFQLADLYEPRGRMTLADIERIAPLEEG-TLPFNLAEAQRQ---------------------------------------------------------------------------------------KASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSA--------------------------LSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASF-------ANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARA-GQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWFYIDFGGVKPMGSEP----VPKSRIN--LPAPNPDHVGGYKLAVATFAGIENKFGLYLPLFKP---SVSTSKAIGGGP----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BH59-1", "uniprot_id": "S2512_MOUSE", "id": "Q8BH59-1", "name": "Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial", "aln": "---------------------------------MAVKVHTTKRGDPHELRNIFLQYASTEVDGEHYMTPEDFVQRYLG-----------LYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFG------------QTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYVEFT---------------QFLQELQLEHARQAFALKDKSKSGMISGLDFSDVMVTIRSHMLTPFVEENLVS------------------------------AAGGGTSHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDIEVTKEEFAQSAIRYGQVT--------------PLEIDILYQLADLYNASGRLTLADIERIAPLAEG-ALPYNLAELQRQ----------------------------------------------------------------------------------------QSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGTGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTKRDGSIPLPAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSA--------------------------LNVLQDLGLFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLL-------ADENGRVGGINLLTAGALAGVPAASLVTPADVIKTRLQVAARA-GQTTYSGVVDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPSGSEP----TPKSRIAD-LPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPSVAVAQPKAAAAAQ----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LX07-1", "uniprot_id": "S2512_RAT", "id": "F1LX07-1", "name": "Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial", "aln": "---------------------------------MAVKVHTTKRGDPHELRNIFLQYASTEVDGEHYMTPEDFVQRYLG-----------LYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFG------------QTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYVEFT---------------QFLQELQLEHARQAFALKDKSKSGMISGLDFSDVMVTIRSHMLTPFVEENLVS------------------------------AAGGSTSHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDIEVTKEEFAS-AITYGVVT--------------PINVGILYFINNVHISTGRLTLADIERIAPLAEG-ALPYNLAELQRQ----------------------------------------------------------------------------------------QSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGTGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSIPLPAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSA--------------------------LNVLQDLGLFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLL-------ADENGHVGGINLLTAGAMAGVPAASLVTPADVIKTRLQVAARA-GQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPSGSEP----TPKSRIAD-LPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPGVAAAQPKVAAAAQ----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75746-1", "uniprot_id": "S2512_HUMAN", "id": "O75746-1", "name": "Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial", "aln": "---------------------------------MAVKVQTTKRGDPHELRNIFLQYASTEVDGERYMTPEDFVQRYLG-----------LYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFG------------QTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFT---------------QFLQELQLEHARQAFALKDKSKSGMISGLDFSDIMVTIRSHMLTPFVEENLVS------------------------------AAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAIRYGQVT--------------PLEIDILYQLADLYNASGRLTLADIERIAPLAEG-ALPYNLAELQRQ----------------------------------------------------------------------------------------QSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSA--------------------------LNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLL-------ADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARA-GQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPAGSEP----TPKSRIAD-LPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPSVAVVQPKAAVAATQ---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VA73-1", "uniprot_id": "CMC_DROME", "id": "Q9VA73-1", "name": "Electrogenic aspartate/glutamate antiporter Aralar, mitochondrial", "aln": "--------------MPMHIPFPFNWIPTLPVARCQESPSLLKRAGTEKLREVFLKYASIQKNGEHYMTSEDFVRKFLG-----------LFSESAFNDESVRLLANIADTSKDGLISFSEFQAFEGLLCTPDALYRTAFQLFDRKGNGTVSYADFADVVQ------------KTELHSKIPFSLDGPFIKRYFGDKKQRLINYAEFT---------------QLLHDFHEEHAMEAFRSKDPAGTGFISPLDFQDIIVNVKRHLLTPGVRDNLVS------------------------------VTEG---HKVSFPYFIAFTSLLNNMELIKQVYLHATEGSRTDMITKDQILLAAQTMSQIT--------------PLEIDILFHLAGAVHQAGRIDYSDLSNIAPEHYTKHMTHRLAEIKAV-----------------------------------------------------------------------------------------ESPADRSAFIQVLESSYRFTLGSFAGAVGATVVYPIDLVKTRMQNQR-AGSYIGEVAYRNSWDCFKKVVRHEGFMGLYRGLLPQLMGVAPEKAIKLTVNDLVRDKLTDKKGNIPTWAEVLAGGCAGASQVVFTNPLEIVKIRLQVAGEIASGSKIRA--------------------------WSVVRELGLFGLYKGARACLLRDVPFSAIYFPTYAHTKAMM-------ADKDGYNHPLTLLAAGAIAGVPAASLVTPADVIKTRLQVVARS-GQTTYTGVWDATKKIMAEEGPRAFWKGTAARVFRSSPQFGVTLVTYELLQRLFYVDFGGTQPKGSEAHKITTPLEQAAASVTTENVDHIGGYRAAVPLLAGVESKFGLYLPRFGRGVTAASPSTATGS------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9DB41-1", "uniprot_id": "GHC2_MOUSE", "id": "Q9DB41-1", "name": "Mitochondrial glutamate carrier 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIACR--------MSSQDLSISAKLING----------------------------------------------------------------------------------------------------------------------------GIAGLVGVTCVFPIDLAKTRLQNQ------QGKDVYRGMTDCLMKTARAEGFLGMYRGAAVNLTLVTPEKAIKLAANDFLRQLLMQDGTQRNLKMEMLAGCGAGICQVVITCPMEMLKIQLQDAGRLAVCHQASASATPTSRPYSTGSTSTHRRPSATLIARELLRTQGLSGLYRGLGATLLRDIPFSIIYFPLFANLNQLG--V----SELTGKASFTHSFVAGCTAGSVAAVAVTPLDVLKTRIQTLKKGLGEDTYSGVTDCARKLWTQEGPAAFMKGAGCRALVIAPLFG-------IAQGVYFIGIG--------------------------------------------ERILKCFE------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q505J6-1", "uniprot_id": "GHC2_RAT", "id": "Q505J6-1", "name": "Mitochondrial glutamate carrier 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIACR--------MSSQDLSITAKLING----------------------------------------------------------------------------------------------------------------------------GIAGLVGVTCVFPIDLAKTRLQNQ------QGKDVYKGMTDCLVKTARAEGFLGMYRGAAVNLTLVTPEKAIKLAANDFLRQLLMQDGTQRNLKMEMLAGCGAGICQVVITCPMEMLKIQLQDAGRLAVCQQASASATPTSRPYSTGSTSTHRRPSATLIAWELLRTQGLSGLYRGLGATLLRDIPFSIIYFPLFANLNQLG--V----SELTGKASFTHSFVAGCAAGSVSAVAVTPLDVLKTRIQTLKKGLGEDTYRGVTDCARKLWTQEGAAAFMKGAGCRALVIAPLFG-------IAQGVYFIGIG--------------------------------------------ERILKCFE------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H1K4-1", "uniprot_id": "GHC2_HUMAN", "id": "Q9H1K4-1", "name": "Mitochondrial glutamate carrier 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTHQDLSITAKLING----------------------------------------------------------------------------------------------------------------------------GVAGLVGVTCVFPIDLAKTRLQNQ------HGKAMYKGMIDCLMKTARAEGFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLFANLNNLG--F----NELAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAGCRALVIAPLFG-------IAQGVYFIGIG--------------------------------------------ERILKCFD------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8INJ3-1", "uniprot_id": "Q8INJ3_DROME", "id": "Q8INJ3-1", "name": "Mitochondrial glutamate carrier 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLEQVEQKN-QEQKKPQKFNVFPKIING----------------------------------------------------------------------------------------------------------------------------GVAGIIGVACVYPLDMVKTRLQNQT--IGPNGERMYTSIADCFRKTIASEGYFGMYRGSAVNIVLITPEKAIKLTANDFFRYHLASDDGVIPLSRATLAGGLAGLFQIVVTTPMELLKIQMQDAGRVAAADRAAG--------------REVKTITALGLTKTLLRERGIFGLYKGVGATGVRDITFSMVYFPLMAWINDQGPRK----SDGSGEAVFYWSLIAGLLSGMTSAFMVTPFDVVKTRLQ----ADGEKKFKGIMDCVNRTLKEEGISAFFKGGLCRIMVLAPLFG-------IAQMFYFLGVG--------------------------------------------EKILGIERTKSV--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGF7-1", "uniprot_id": "Q9VGF7_DROME", "id": "Q9VGF7-1", "name": "Mitochondrial glutamate carrier 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSSATIATPLPQPQHQQFALLPKIING----------------------------------------------------------------------------------------------------------------------------GIAGIIGVTCVFPLDLVKTRLQNQQ--IGPNGERMYNSMFDCFRKTYKAEGYFGMYRGSGVNILLITPEKAIKLTANDYFRHKLTTKDGKLPLTSQMVAGGLAGAFQIIVTTPMELLKIQMQDAGRVAAAAKLAG--------------KTVEKVSATQLASQLIKDKGIFGLYKGIGATGLRDVTFSIIYFPLFATLNDLGPRR----NDGSGEAVFWCSFLAGLAAGSTAALAVNPFDVVKTRLQAIKKADGEKEFKGISDCITKTLKHEGPTAFFKGGLCRMIVIAPLFG-------IAQTVYYLGVA--------------------------------------------EGLLGYQKK-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12482-1", "uniprot_id": "AGC1_YEAST", "id": "Q12482-1", "name": "Mitochondrial aspartate-glutamate transporter AGC1", "aln": "MEQINSNSRKKKQQLEVFKYFASVLTKEDKPISISNGMLDMPTVNSSKLTAGNGKPDTEKLTGELILTYDDFIELISSSKTIYSKFTDHSFNLNQIPKNVFGCIFFAIDEQNKGYLTLNDWFYFNNLLEYDNYHLIILYEFFRKFDVENLKAKQKKELGSSSFNLKAADDRIKSINYGNRFLSFDDLLLNLNQFKDTIRLLHESIDDNFVKDNKLLLDWNDFRFLKFYKCYHENEEYLSLNSLVTILQNDLKNEKIFIGFDRLAQMDSQGHRLALSKNQLTYLLRLFYSHRVSADIFSSLNLSNTELLKADNNSIPYNVFKDIFYLFQNFDLLNQIFHKYVTENNLNEQDIREQIVTKNDFMTVLNAQYNKVNNIIEFSPSQINLLFSIVANSKENRRLRKRNQDRDDELLNDHHYDSDIDFFIHNEYLHGVSRSRKNLESFNDYYHDLSDGFDQDSGVKKASKASTGLFESVFGGKKDKATMRSDLTIEDFMKILNPNYLNDLVHQMELQKNQNESLYINYYFYPIFDSLYNFSLGSIAGCIGATVVYPIDFIKTRMQAQR------SLAQYKNSIDCLLKIISREGIKGLYSGLGPQLIGVAPEKAIKLTVNDFMRNRLTDKNGKLSLFPEIISGASAGACQVIFTNPLEIVKIRLQVQSDYVGENIQQAN----------------------ETATQIVKKLGLRGLYNGVAACLMRDVPFSAIYFPTYAHLKKDLFDFDPNDKTKRNRLKTWELLTAGAIAGMPAAFLTTPFDVIKTRLQIDPRK-GETKYNGIFHAIRTILKEESFRSFFKGGGARVLRSSPQFGFTLAAYELFKGFIPSPDNKLKSREGRK-----RFCIDDDAGNEETVVHSNGELPQQKFYSDDRKHANYYYKSCQIAKTFIDLDNNFSRFDSSVYKNFQEHLRSING", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ..** :*.: *:*:*: ***:* * . * . **: * ** *:* * :: ::*******:.** .* : .:* ** *::.* *:*::**::* . . . ::: *: *:*.* * :**:.** :*** * : . : :* :* :* ..* **:***:* *: : *: .. .*. :: ** .* : :* ** : : . ", "identical_positions": 72, "similar_positions": 70, "identity": "7.69%" }, { "cls_id": "homologset.agr.SGD:S000006227", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60762-1", "uniprot_id": "MO4L1_MOUSE", "id": "P60762-1", "name": "Mortality factor 4-like protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAP-KQDPKPKFQEGERV-------------------LCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKKSAVRPRRSEKSLKTREDIVALFPVPEGAPSVHHPLLTSSWDEWVPESRVLKYVDTNLQKQRELQKANQEQYAEG---------KMRGAAPGK--------KTSGLQQKNVEVKTKKNKQKTPGNGDGGSTS------------ETP--------------------------------------------------------QPPRKKRARVDP-------------------------------------TVE--NEE---------------------------------------------------------------------------------------------------------------------------------------------------------------------TFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKKS-RGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAP----MSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSATLFSASD--------YEVAPPEYHRKAV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBU8-1", "uniprot_id": "MO4L1_HUMAN", "id": "Q9UBU8-1", "name": "Mortality factor 4-like protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAP-KQDPKPKFQEGERV-------------------LCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKKSAVRPRRSEKSLKTHEDIVALFPVPEGAPSVHHPLLTSSWDEWVPESRVLKYVDTNLQKQRELQKANQEQYAEG---------KMRGAAPGK--------KTSGLQQKNVEVKTKKNKQKTPGNGDGGSTS------------ETP--------------------------------------------------------QPPRKKRARVDP-------------------------------------TVE--NEE---------------------------------------------------------------------------------------------------------------------------------------------------------------------TFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKKS-RGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAP----MSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSATLFSASD--------YEVAPPEYHRKAV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6AYU1-1", "uniprot_id": "MO4L1_RAT", "id": "Q6AYU1-1", "name": "Mortality factor 4-like protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAP-KQDPKPKFQEGERV-------------------LCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKN---------------------------------------WDEWVPESRVLKYVDANLQKQRELQKANQEQYAEG---------KMRGAAPGK--------KTSGLQQKNVEVKTKKNKQKTPGNGDGGSTS------------ETP--------------------------------------------------------QPPRKKRARVDP-------------------------------------TVE--NEE---------------------------------------------------------------------------------------------------------------------------------------------------------------------TFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKKS-RGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAP----MSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSATLFSASD--------YEVAPPEYHRKAV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0Q4-1", "uniprot_id": "MO4L2_MOUSE", "id": "Q9R0Q4-1", "name": "Mortality factor 4-like protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSRKQASQTRGQQSAEE-------------------DNFKKPTRSNMQRSKMRG----------------------------------------------------------------------AASGKKSAGSQPKNLDPALPG---------RWGGRSAEN--------PPSGSVR-----KTRKNKQKAPGNGDGGSTS------------EVP--------------------------------------------------------QPPRKKRARADP-------------------------------------TVE--SEE---------------------------------------------------------------------------------------------------------------------------------------------------------------------AFKSRMEVKVKIPEELKPWLVEDWDLVTRQKQLFQLPAKKNVDAILEEYANCKKS-QGNVDNKEYAVNEVVGGIKEYFNVMLGTQLLYKFERPQYAEILLAHPDAP----MSQIYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASD--------YKVASADYHRKAL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6QI89-1", "uniprot_id": "MO4L2_RAT", "id": "Q6QI89-1", "name": "Mortality factor 4-like protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSRKQASQTRGQQSAEE-------------------DNFKKPTRSNMQRSKMRG----------------------------------------------------------------------AASGKKSAGSQPKNLDPALPG---------RWGGRSAEN--------PPSGSVR-----KTRKNKQKTPGNGDGGSTS------------EVP--------------------------------------------------------QPPRKKRARADP-------------------------------------TVE--SEE---------------------------------------------------------------------------------------------------------------------------------------------------------------------AFKSRMEVKVKIPEELKPWLVEDWDLVTRQKQLFQLPAKKNVDAILEEYANCKKS-QGNVDNKEYAVNEVVGGIKEYFNVMLGTQLLYKFERPQYAEILLAHPDAP----MSQIYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASD--------YKVASADYHRKAL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15014-1", "uniprot_id": "MO4L2_HUMAN", "id": "Q15014-1", "name": "Mortality factor 4-like protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSRKQGSQPRGQQSAEE-------------------ENFKKPTRSNMQRSKMRG----------------------------------------------------------------------ASSGKKTAGPQQKNLEPALPG---------RWGGRSAEN--------PPSGSVR-----KTRKNKQKTPGNGDGGSTS------------EAP--------------------------------------------------------QPPRKKRARADP-------------------------------------TVE--SEE---------------------------------------------------------------------------------------------------------------------------------------------------------------------AFKNRMEVKVKIPEELKPWLVEDWDLVTRQKQLFQLPAKKNVDAILEEYANCKKS-QGNVDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILLAHPDAP----MSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASD--------YKVASAEYHRKAL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LME2-1", "uniprot_id": "A0ABK0LME2_RAT", "id": "A0ABK0LME2-1", "name": "", "aln": "MSSKKKGPYLCDQQFAEGDDFSKLKPSDRRVRKARSVSSPQKSTELRSLQSTLQRRRRARSVKKSHSVEKSYSEEKTCAVEKIPSTEKAYSTKKNPSAEKRRSVAKKHHTIVKSSSTEKLLLAEKHAYAEKCLTTEKRSSAEKHPPTLKGRMTQKSASAGRHHSESHRSGKTLRFPEKSNIKENHHSSVKHSSLEKDHPEDRGRPIKKRCPTEKSQSTEKGQLTERSSYAPATERGRPTKRSQPTKKGLSNENRHPAKKGYSAKTPGSAERDHQIERGGATDSGLSTEKDCPSRRRRPAKKSHLEEKVHSQKSSYESRVISAEKDGLAGRVRRKRSNPSEEGHSVKCSICDSSVPSAGKDRPVRSRSDKSNPGEDRRSVESGISASRGPSAGKDSPAGRGRPNKIRRAEKGHSMEYGSSAPRGPSAGKDRPGGRGHPNKSGPTEESRSVESDTCASKGPSTTGKERPVRRCRLNKNSLAERLCSIQCGICTPRGPSAGKHCSERRGRPNKRVPAEEDRSLKNISASRRPSGGKDRPARSRSNKSGPTKEGWSVEGSRSTSGRPSEGKDRSGGRGRPNKSGPEKEGPSVNDSRSTSRGPSAGKDRSARRSSSNKSGPTEESLSDERDICESRGPSTGKERPARKCRLNKNSLAEQWCSIKCGICALKQFSTRKDHSRERGRSKESGVEVGSHLVKSGVSTPRGPSAGKDLPAGRGRPNKSSPAEEGCSVKSSISASRRPSVGRDRPARSCSNKSGSAEESCSVKCGICTPKVPSAGKDRPGGRGCPNKNSPKKEDPSVKGGRSTSRGPSAGKDRSGGRGHTNKSGPAEESRSVEGSRSTSRGPSAGKDRSGRRRHTNKSGPAEESRSVEGIRSTSRGPSAGKDRPGRRGYPNKSSPKKEGPSVKGSRSTSRGPSAGKDRSGGRGHTNKSGSAEESHSVEGSRSTSRGPSAGKDRPGRRGYPNKNSPKKEGPSVKGSRSTSRGPSAGKDRPGGRGYPNKSSPKKEGPSVKGSRSTSRGPSAGKDRPGRRGYPNKSSPKKEGPSVKGSRSTSRGPSAGKDRPGRRGYPNKNIPKKEGPSVKCSRNTSRGSSAGKDRPGGRGRSNKSSPTEESRSVEGSRSTSRGPSAGKDRPGRRGYPNKSSPKKEGSSVKGSRSTSRGPSAGKDRPGRRSYPNKSSPKKEGPSVKGSRSTSRGPSAGKDRPGGRSHLNECGPEKKCPSVKDSRSTSRGPSAGKDRPGRRGRSNKSSPTEESRSVEGSRSTSRGPSAGKDRPGRRGYPNKSSPKKEGPSVKGSRSTSRGPSAGKDHPGRRSYPNKSSPKKEGPSVKGSRSTSRGPSAGKDRPGRRGYPNKSSPKKEGPSVKGSRSTSRGPSAGKDRPGRRGYPNKNISKKEGPSVKCSRSTSRGSSAGKDRPGGRGRSNKSSPTEESRSVEGIRSTSRGPSVGKDRPGRRGYPNKNIPKKEGPSVKCSRSTSRGSSAGKDRPGGRGRSSKSSPTEESRSVEGIRSTSRGPSVGKDHSGKRGHPSKRGPEEEGPSFKGSRSTSRRPSVGKDRSGGRGHSNKSGPEKGDPSVKGRLSISRGSSVGKDHSGGRGHPNERGPEKEGPSAKGSRSTSRGPSVGKDRSGGRGHSNKSGPEKEGPSVKGSRSTSRGSSVGKDRRGGRGHSNKSGPEREDPSVKGSHNTSRGPSLGKDRPGGRGHPNKSGPAEKIRSVESSTCASKEPSAGNERPARRYHSNKSSLAEGCCSIKSGICVPRGPSAGNDHCGRGRPNKSGSAKKSHSVEHSSNISRGPSAGKDRSTSRSGPSKKNQLAQEGPSKEKESYAKRGPSKRKEHHAGRRPNSSQHEEEFRSFGRGKSKRGPSAGKDHPTGKGQPPKKSRPEKDSSSAERGNHAERGQSTGKDHPTDRGQPRKKSHPEEVGHSVEKGNEERKPSAGKDPHTKRGRPSKKSHPAERHLSASMKYCPPKKHRPAENVCVKRVRSPERVHSMERGHIAKRSCLAERQLSAEEGSMAEEGCSVETDLSEERAEEGTVVDNMCSVENGHPSMEKVFLEVKPSSGSMSRVTEPNNLQSTPEKRIDSDTNQVAQVPHCNLPVTVKIKMGVELRVPDELKSRLVEDWDLINKQKQLFQLPAEKNVDTILAEYVTFVKS-QGLADNREYSVDEVVAGIREYFNRMLGTQLLCQFEKPQYAEIHLAYPDIP----MSQVYGAPHLLRLFVKIGTALANSPLNRQSLLLVSSYMHDFLEYLAENSTSLFKVSN--------YKVASAEYCCKAL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y0I1-1", "uniprot_id": "EAF3_DROME", "id": "Q9Y0I1-1", "name": "NuA4 complex subunit EAF3 homolog", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGEVKPAKVEN-YSTGTDANTLFVDGERVLCFHGPLIYEAKVLKTKPDATPVEYYIHYAGWSKNWDEWVPENRVLKYNDDNVKRRQELARQCGERSKK------------------DNKKGSAKAKKMEQMRNESRASTPSKDSNTSQSTASSTP-------------------TTSAGPGSKSEAGSTGTTTTN------------------------------------------------------------------STANSTTSRAHRKSTQSTPSTA---------RPGTPSDKKE-------DPAAAETTEEEGPVAPKKKRMSEQRPSLTGS---------DVAEKP--------------------------------------------------------LPPTTTPSTPTTEPAP---------------------------------CVE--SEE---------------------------------------------------------------------------------------------------------------------------------------------------------------------AYAAKVEVKIKIPDELKHYLTDDWYAVVREHKLLELPAKVTVQQISEQYLAHKKSVKSTSASKEVAINDVLDGIVEYFNVMLGSQLLYKFERTQYADVMQKHPDTP----LSELYGSFHLLRLFVRLGSMLSYSALDQQSMQNLLTHVQDFLKFLVKNSSIFFSMSN--------FINVDPEYVRNAQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12432-1", "uniprot_id": "EAF3_YEAST", "id": "Q12432-1", "name": "Chromatin modification-related protein EAF3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVDLEQEFALGGRCLAFHGPLMYEAKILKIWDPSSKMYTSIP-NDKPGGSSQATKEIKPQKLGEDESIPEEIINGKCFFIHYQG----------------WKSSWDEWVGYDRIRAYNEENIAMKKRLANEAKEAKKSLLE------------------QQKKKKLSTSLGGPSNGGKR--------------------------------------------------------------------KGDSRSNASISKSTSQSFLTS---------SVSGRKSGR--------SSANSLHPGSSLRSSSDQNGNDDRRRSSSLS------------------------------------------------------------------------PNMLHHIAGYP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPKISLQIPIKLKSVLVDDWEYVTKDKKICRLPADVTVEMVLNKYEHEVSQ-ELESPGSQSQLSEYCAGLKLYFDKCLGNMLLYRLERLQYDELLKKSSKDQKPLVPIRIYGAIHLLRLISVLPELISSTTMDLQSCQLLIKQTEDFLVWLLMHVDEYFNDKDPNRSDDALYVNTSSQYEGVALGM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: . . . . . . : . . . : * * . :.:::* :** *.:** : ::::: ***. .*: : .* .. . . : :.: *: **: **. ** ::*: ** :: .. .:**: *****: : :: :.:: :* : .*** :* : *. .: : . .:* * ", "identical_positions": 38, "similar_positions": 75, "identity": "1.67%" }, { "cls_id": "homologset.agr.SGD:S000006228", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q925S8-1", "uniprot_id": "YMEL1_RAT", "id": "Q925S8-1", "name": "ATP-dependent zinc metalloprotease YME1L1", "aln": "MFSLSSTVQPQVTV-------PLSHLIN--AFHSPKNISVSVN-TSASPKQHRDTVAEHEAPSSE---------------------------------------------------------PVLNLRDLGLS-ELKIGQIDKLVENLLPGFYKDKRVSSCWHTSHISAQSFFENKYGHLDMFSTLRSSSLYRQHPKTLQSICSDLQNFPVFIQS-----RGFKT---LKSRTRRLQSTSERLAEAQNIAPSFVKGFLLRDRGTDLESLDKLMK-TKNIPEAHQDAFKTGFAEGFLKAQ-----ALTQKTNDSLRRTRLILFVLLLFGIYG-LLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTVLGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIEFPMHPYSRQTIIQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDKSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNEIRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTG------KLSPETQSAIEQEIRILLRESYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88967-1", "uniprot_id": "YMEL1_MOUSE", "id": "O88967-1", "name": "ATP-dependent zinc metalloprotease YME1L1", "aln": "MFSLSSTVQPQVTI-------PLSHLIN--AFHSPKNISVSVN-TPVSQKQHRDTVPEHEAPSSE---------------------------------------------------------PVLNLRDLGLS-ELKIGQIDKMVENLLPGFYKDKRVSSCWHTSHISAQSFFENKYGHLDMFSTLRSSSLYRQHPKTLRSICSDLQYFPVFIQS-----RGFKT---LKSRTRRLQSTSERLVEAQNIAPSFVKGFLLRDRGTDLESLDKLMK-TKNIPEAHQDAFKTGFAEGFLKAQ-----ALTQKTNDSLRRTRLILFVLLLFGIYG-LLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTVLGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDKSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTG------KLSPETQSAIEQEIRILLRESYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96TA2-1", "uniprot_id": "YMEL1_HUMAN", "id": "Q96TA2-1", "name": "ATP-dependent zinc metalloprotease YME1L1", "aln": "MFSLSSTVQPQVTV-------PLSHLIN--AFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSECMFSDFLTKLNIVSIGKGKIFEGYRSMFMEPAKRMKKSLDTTDNWHIRPEPFSLSIPPSLNLRDLGLS-ELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLRSSCLYRHHSRALQSICSDLQYWPVFIQS-----RGFKT---LKSRTRRLQSTSERLAETQNIAPSFVKGFLLRDRGSDVESLDKLMK-TKNIPEAHQDAFKTGFAEGFLKAQ-----ALTQKTNDSLRRTRLILFVLLLFGIYG-LLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTG------KLSPETQSAIEQEIRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F3YDF1-1", "uniprot_id": "YMEL1_DROME", "id": "F3YDF1-1", "name": "ATP-dependent zinc metalloprotease YME1L", "aln": "MFSTTTHSVPYLYLGNF-SRKPHYYSVNRTKLHGSAGAARLSKSTSTSSRSHDLVLDLRNLLSRSS-----------------------------------------------------ASIQGMVERAARLNGILDRRLVDDVLAKVTSMLPSMRDVRVTLEESATQIGRVQLQNYQFEVSLTGAAGSVPTGANVKVIPTITPGLLR-PLFSQQQLNQIRGFKTDRSIEAEQKRNPTMTSRLKNALANSPQRLDG----DTPLQAEKLRRLLAKSEEHGFNKAESLKIAFAEGYLAAANSEDSPKSGKTMKYLKTLQTIVVIVVFLGIFLSFFTTSNGSVFRSIQLGNQVEVDPEEIN-VTFEDVKGCDEAKQELKEVVEFLKSPEKFSNLGGKLPKGVLLVGPPGTGKTLLARAVAGEAKVPFFHAAGPEFDEVLVGQGARRVRDLFKAAKARAPCVIFIDEIDSVGAKRTNSVLHPYANQTINQLLSEMDGFHQNAGVIVLGATNRRDDLDQALLRPGRFDVEVMVSTPDFTGRKEILSLYLTKILHDE-IDLDMLARGTSGFTGADLENMINQAALRAAIDGAETVSMKHLETARDKVLMGPERKARLPDEEANTITAYHEGGHAIVAFYTKESHPLHKVTIMPRGPSLGHTAYIPEKERYHVTKAQLLAMMDTMMGGRAAEELVFGTDKITSGASSDLKQATSIATHMVRDWGMSDKVGLRTIEASKGLGTGDTLGPNTIEAVDAEIKRILSDSYERAKAILRKHTREHKALAEALLKYETLDADDIKAILNESQT-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32795-1", "uniprot_id": "YME1_YEAST", "id": "P32795-1", "name": "Mitochondrial inner membrane i-AAA protease supercomplex subunit YME1", "aln": "MNVSKILVSPTVTTNVLRIFAPRLPQIGASLLVQKKWALRSKKFYRFYSEKNSGEMPPKKEADSSG--------------------------------------------------------KASNKSTISSIDNSQPPPPSNTNDKTKQANVAVSHAMLATREQEANKDLTSPDAQAAFYKLLLQSNYPQYVVSRFETPGIASSPECMELYMEA-------------LQRIGRHSEADAVRQNLLTASSAGAVNPSLASSSSNQSGYHGNFPSMYSPLYGSRKEPLHVVVSESTFTVVS-------------RWVKWLLVFGILTYSFSEGFKYITENTTLLKSSEVADKSVDVAKTN-VKFDDVCGCDEARAELEEIVDFLKDPTKYESLGGKLPKGVLLTGPPGTGKTLLARATAGEAGVDFFFMSGSEFDEVYVGVGAKRIRDLFAQARSRAPAIIFIDELDAIGGKRNPK-DQAYAKQTLNQLLVELDGFSQTSGIIIIGATNFPEALDKALTRPGRFDKVVNVDLPDVRGRADILKHHMKKITLADNVDPTIIARGTPGLSGAELANLVNQAAVYACQKNAVSVDMSHFEWAKDKILMGAERKTMVLTDAARKATAFHEAGHAIMAKYTNGATPLYKATILPRGRALGITFQLPEMDKVDITKRECQARLDVCMGGKIAEELIYGKDNTTSGCGSDLQSATGTARAMVTQYGMSDDVGPVNLSENWES-----WSNKIRDIADNEVIELLKDSEERARRLLTKKNVELHRLAQGLIEYETLDAHEIEQVCKGEKLDKLKTSTNTVVEGPDSDERKDIGDDKPKIPTMLNA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . * : * :. : . ..: : :: . . . .. : . . . : : . * .. :: : :: :: : : * :. :. . : .: . : :.:: .:*. : . ::. :: .: : . :. : ** : : *.*:.* * :**: **:*:*:***.* *: ********:**.*************.**** * *:. :*.****: ** ** *:*:** *::.**.:*****:*::*.** :.*:.**: *** *:*** . *:*::**** : **:** ****** * * **. ** :**. ::.** . :* ::**** *::**:* *::****: *. .. * *..:* ::**:***.**:: : .. **:**.****:* **: : *: *.**:*** :** . :** :: . : : * :*. ***: ****::*.*: *:*..**:..** * ** .:***:.:* . . . . : . : *: :* :* ***: :* .: * : **:.*: ******.:*: : : .: ", "identical_positions": 202, "similar_positions": 199, "identity": "24.16%" }, { "cls_id": "homologset.agr.SGD:S000006229", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61458-1", "uniprot_id": "CCNH_MOUSE", "id": "Q61458-1", "name": "Cyclin-H", "aln": "-----------------------------------------------MYHSSSQKRHWTFASEEQLARLRADANRKFKCKAVA--------------NGKVLPNDPVFLEPHEELTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQERALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDIKTRYPMLENPEILRKTAD---DFLSRIALTDAYLLYTPSQIALTAILSS---------ASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSDEVAVLKQKLERCHSSDLALNAVTKKRKG---YED-DDYVSKKPKQEEEEWTDDDLVDSL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R1A0-1", "uniprot_id": "CCNH_RAT", "id": "Q9R1A0-1", "name": "Cyclin-H", "aln": "-----------------------------------------------MYHNSSQKRHWTFASEEQLARLRADANRKFKCKAVA--------------NGKVLPNDPLFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDIKTRYPMLENPEILRKTAD---DFLSRIALTDAYLLYTPSQIALTAILSS---------ASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAILKQKLERCHSSDLALNMVTKKRKG---YED-DDYVSKKPKQEEEEWTDDDLVDAL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51946-1", "uniprot_id": "CCNH_HUMAN", "id": "P51946-1", "name": "Cyclin-H", "aln": "-----------------------------------------------MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVA--------------NGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTAD---DFLNRIALTDAYLLYTPSQIALTAILSS---------ASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKG---YED-DDYVSKKSKHEEEEWTDDDLVESL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JIW9-1", "uniprot_id": "A0AC58JIW9_DANRE", "id": "A0AC58JIW9-1", "name": "Cyclin-H", "aln": "-----------------------------------MRMHLPRGRGLNMYHNSSQKKFWTYDKEETLDKLRLEANQKFCSKALS--------------SGKPGINESTLLNEQEEKVLFKHYEKRLLDFCAVFKPVMPKSVVGTACMYFRRFYLNNSLMEYHPRTIMLTCAYLSCKVDEFNVSSTQFVGNLQESPAGQERAVDQILEYELLLIQQLNFHLVVHNPYRPLEGFLIDLKTRYPLLENPEMLRKSAE---DFLNRATMTDAGLLFSPSQIALTAVLNS---------AARAGLKMDVYLNECMGLKEDKETLSKMYESMRRMTSLVKAYELPKAEEVSICKQKLERIY-AEFATN--LKRKHG---YED-DDHVVKRQMVADEEWTDDDL-DAL---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O76513-1", "uniprot_id": "O76513_DROME", "id": "O76513-1", "name": "Cyclin-H", "aln": "-----------------------------------------------MYPVSSQKRSWTFANEGQLMEFRVEQNSKYIESHEE--------------EAQGRDLNEHFLTSAEERLLLKQYEIYLFDFCRRFEPTMPKCVVGTAFHYFKRFYLNNSPMDYHPKEILATCVFVACKVEEFNVSINQFVNNIKGD---RNKATDIVLSNELLLIGQLNYYLTIHNPFRPIEGFLIDIKTRSNMQ-NPDRLRPHID---SFIDSTYYSDACLLHTPSQIALAAVLHA---------ASREQENLDSYVTDLLFVS-AREKLPGLIDAVRKIRIMVKQYQQPDREKVKAIEKKLDKCRNQANNPDSELYKERLRRLYTDEDDMPAEDASFHIADVSSDTSAMNISQ-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P37366-1", "uniprot_id": "CCL1_YEAST", "id": "P37366-1", "name": "Cyclin CCL1", "aln": "MTDIQLNGKSTLDTPSATMSAKEKEAKLKSADENNKPPNYKRISDDDLYRHSSQYRMWSYTKD-QLQEKRVDTNARAIAYIEENLLKFREAHNLTEEEIKVLEAKAIPLTMEEELDLVNFYAKKVQVIAQHLN--LPTEVVATAISFFRRFFLENSVMQIDPKSIVHTTIFLACKSENYFISVDSFAQKAKSTR-------DSVLKFEFKLLESLKFSLLNHHPYKPLHGFFLDIQNVLYGKVDLNYMGQIYDRCKKRITAALLTDVVYFYTPPQITLATLLIEDEALVTRYLETKFPSREGSQESVPGNEKEEPQNDASTTEKNKEKSTESEEYSIDSAKLLTIIRECKSIIEDCKPPSTEEAKKIAAKNYYCQNPSTLIQKLKRKLNGEDTSSTVEKKQKT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *** : *:: .: * . * : * : . : . * ** * : * : :. :: :* **.** :*:**:*:** *: .*: *: * :::** ::: :* .*. : : : :*. *: *: .*:: * *:*::*:.**::*::. : : : : . : :*. :.:*.**:*:::* :: . . . : : : *. . : .: . : * : . : . ", "identical_positions": 51, "similar_positions": 92, "identity": "12.66%" }, { "cls_id": "homologset.agr.SGD:S000006230", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZY02-1", "uniprot_id": "D3ZY02_RAT", "id": "D3ZY02-1", "name": "Protein-glucosylgalactosylhydroxylysine glucosidase", "aln": "---------------------------------------------------------------------------------------------------------------------------MDCSEDDPTRFSADCLPSDPRLWATVTNSYLGTRI----YHDTIHINGVYNGAGGDTHR-----------------------------------------AILPSPLNVHLEAP----------AGT-EQLTETFTLDTNTGSF--LHTLESSSFRASQCIYAHRVLPHVLVFSVSIARLTTGNEPIT-------VPLRADFSPESPDLDLHVGPDFQG-LRYLHGHTLIPEHP--GEPRPEVHMLWVP---VPPALTLGEDEKDRTWEFVTVVGSS------------------------QAEAQGCYAEALQLQTRG---VLYTIHADTWGQLWA-GCGLDVAG-PLALRQALRGSLYYLFSELP---KPGTQGSTSHGLSPGGLSNGSQEECYWGHIFWDQDLWMFPNILMFHPEAARAILEYRIRTLGGALKNAQNLGYQGAKFAWESAGTGLEVCP--EDIYGTQEIHINGAVVLAFQLYYYY--TQDLQLFQEDGGWDVVSSVAEFWCSRVEWSSQDKMYHLKGVMPPDEYHSGVNNSVYTNVLVQNSLHFAAALAEDLGLPVPK---QWLEVADRIKVPFDSEQNFHPEFDGYERGEEVKQADVVLLGYPVPFPLRPDIRRK---NLETYEAVTSPRGPAMTWSMFAVGWMELKDP-SRAQVHLNRSFAN-VTEPFKVWTENANG--------SGAVNFLTGMGGFLQAALFGCTGFRITAAGV----------TFDPLCPDLVS-KVSVSGVSYLGNKLNFAFSKDLVTLEVTARAEPGAPLLEAELWPSLARLTLSPGQK----------------------------VSFPHTAGRIQRSTSIAAQKFI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BP56-1", "uniprot_id": "PGGHG_MOUSE", "id": "Q8BP56-1", "name": "Protein-glucosylgalactosylhydroxylysine glucosidase", "aln": "---------------------------------------------------------------------------------------------------------------------------MDGSEDDPTIFSARCLPSDPRLWATVTNSYLGTRV----YHDTIHINGVYNGAVGDTHR-----------------------------------------ASLPSPLNVQLEAP----------AGT-EQLTETFTLDTNTGSF--LHTLEGPSFRASQRIYAHRVLPHVLVFSVSIARLTTGNKPIT-------VPLRADFSPESPDLDLRVGPDFQG-LRYLHGHVLNPEQP--GEPQQEVHMLWMP---VPPALTLGEEEKDRTWEFLTVVGSS------------------------QAEAQDCFAEALQLQTRG---VLYTIHADSWGRLWA-GCGLDVAG-PLALRQALRGSLYYLFSELP---QPGTQGFISHGLSPGGLSNGSKEECYWGHIFWDQDIWMFPNILMFHPEAARAILEYRVRTLGGALKNGQNLGYQGAKFAWESASTGLEVCP--EDIYGTQEIHINGAVALAFQLYYYY--TQDSKLFQEDGGWDVVSSVAEFWCSRVEWSSQDKMYHLKGVMPPDEYHSGVNNSVYTNVLVQNSLHFAAALAKDLGLPIRK---QWLEVADRIKIPFDSEQNFHPEFDGYERGEEVKQADVVLLGYPVPFPLTPDIRRK---NLETYEAVTSPQGPAMTWSMFAVGWMELRDP-SRAQVHLSRSFAN-VTEPFKVWTENADG--------SGAVNFLTGMGGFLQAALFGCTGFRITEAGV----------TFDPLCPDLVS-RVSVSGISYLGNKINFAFSKDSVTLEVTARAEPWAPLLEAELWPSLAHLPLTPGQK----------------------------VSFPHSAGRIQRSSP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q32M88-1", "uniprot_id": "PGGHG_HUMAN", "id": "Q32M88-1", "name": "Protein-glucosylgalactosylhydroxylysine glucosidase", "aln": "---------------------------------------------------------------------------------------------------------------------------MEDAGEDPTTFAAHSLPSDPRLLATVTNAYLGTRV----FHDTLHVSGVYNGAGGDTHR-----------------------------------------AMLPSPLNVRLEAP----------AGMGEQLTETFALDTNTGSF--LHTLEGPRFRASQCIYAHRTLPHVLAFRVSIARLAPGSGPIT-------LLLRSAFSPESPDLDLHQGPDFQG-ARYLYGHTLTPEQP--GGPQQEVHMLWTP---APPDLTLGEGEEARTWDFLTAVGGS------------------------QAEAQACLTEALQLQARG---ALYTAHAQAWAQLWV-ECGLDVVG-PLQLRQALRGSLYYLLSALP---QPKAPGYICHGLSPGGLSNGSREECYWGHVFWDQDLWMFPSILMFHPEAARAILEYRIRTLDGALENAQNLGYQGAKFAWESADSGLEVCP--EDIYGVQEVHVNGAVVLAFELYYHT--TQDLQLFREAGGWDVVRAVAEFWCSRVEWSPREEKYHLRGVMSPDEYHSGVNNSVYTNVLVQNSLRFAAALAQDLGLPIPS---QWLAVADKIKVPFDVEQNFHPEFDGYEPGEVVKQADVVLLGYPVPFSLSPDVRRK---NLEIYEAVTSPQGPAMTWSMFAVGWMELKDA-VRARGLLDRSFAN-MAEPFKVWTENADG--------SGAVNFLTGMGGFLQAVVFGCTGFRVTRAGV----------TFDPVCLSGIS-RVSVSGIFYQGNKLNFSFSEDSVTVEVTARAGPWAPHLEAELWPSQSRLSLLPGHK----------------------------VSFPRSAGRIQMSPPKLPGSSSSEFPGRTFSDVRDPLQSPLWVTLGSSSPTESLTVDPASE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0JMP0-1", "uniprot_id": "PGGHG_DANRE", "id": "A0JMP0-1", "name": "Protein-glucosylgalactosylhydroxylysine glucosidase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGVYNGDGGTCHR-----------------------------------------GNIPCPLAAQMKTG----------EVG----RQLYELNMHTGVF--SHTVVTSDFEAIQVLYAHRNQSNLLVMEILLKRIKTSAEPIT-------IQLESSFKPQSEDIAFQNAPDYKG-GRHIFGQTASSEVP--GGVRPVVHLIWTP---VTPTLTLPANQSQSSWTFLVAVARS------------------------NESAQSFYDSGLALINTG---DLRPSHQRSWAELWK-GSSIEVIG-AESLNRALIGCMFYLLGSFPYVNKEASAAFEFGGVSPGGLSNGSEDEDYHGHVFWDQDTWMYPSIALFYPALARAVLQYRVETLEGAQVNAQQMGCKGLKFAWESAVTGVDVCP--EDVYSQQELHINGDVILAFQQYYYL--TQDLELFQSGRGSEVVWGVADFWVSRVTWDSADQQYHIKGVIPPDEYYFTVDNSVFTNAVAQRSLEFAVELSALLAEVPPP---AWQDIADKIKIPFDPELKFHPEFDGYKPGNKVKQADVVLLGFPLAFPMSPEIRRN---DLEMYEAVTDPLGPAMTWGMFALGWLELGEA-EKAQKLLQKCFKN-VQKPFQVWSESADG--------SGCVNFLTGMGGFLQAVLFGYTGFRVQKEQL----------AFSPLLPLDVS-ALSVKGVCYLGHKMDWTITSEEVKVSVRKTDSKETFTLQVVLN-SGSTLLLTPGQS----------------------------VSFPRQPGHICQLKSSSSCWPI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKD9-1", "uniprot_id": "Q9VKD9_DROME", "id": "Q9VKD9-1", "name": "Glycoside hydrolase family 65 central catalytic domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------MRKSIVFIGLIALFQSCLAETPETYLLKTHSLPSDLNFMPTLGNGHVGYTI----FGDAIFMNGVYNGAGGNSKR-----------------------------------------ARIPNWINISTEACDRFGCA----TDSDVVNGTSYEMNLRDGYFRVVTTYRGLGISVEQRTYPHKYYNRALVYEVVANRLAGRNSRINSPKFLRLTQFAGNFSDAFDFVVVNNGSSASGNYRTLRGQTKVVENEQFQPDPQEIFVLFSESLEQPLELQWPTWQDQLSHRVIIAIDRD------------------------ESVTRKELQDVLQLSSD----NLLQKHSQSWNSFWDDEFSIEIKGDALELSQIVNAGIFYIVSSLP-SLETNQKNELFYGLSPTGLGRGNLEADYQGHNFWDTEIWMLPIVSLFGLDYAKEVLGYRSRKLEAAKYHANATGYKGARFPWESAYTGTEVTNPCCPEVAEQEIHISPDISFALQKFFAQ--SND-SEWTCGTAWPITADVADFLVSRATCDDSTKTCHLLNVMGPDEDHPNVNDNVYTNAVSKIALNFAEWLAKHCGNASTERLEKWREVSDGLVILRDESLNYHPEYAGYVRDTIIKQADTILLGYPLNFDKS-STHIN---DLRFYANVTRESGPAMTWSMFAANYLRNLQL-TLANEYFERGYKSYVRPEFKVWSETPIGY-------DGSANFLTGIGGFLQALIFGYGGLDFGRTDD----------DQFLMFFGISL-TPPNVEEVFINSIPYGQHAKCTLRFKSRHSEISCYDRIGKGFKMAQGQKRTILGRS----------------------------FNLTRQNEDPPIEISFLR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48016-1", "uniprot_id": "ATH1_YEAST", "id": "P48016-1", "name": "Periplasmic acid trehalase ATH1", "aln": "MKRIRSLWFNAEASYSNLNNSPSLRNKNSTGNNSRSKNYRSFSRFDLINSILLLMMLFLLAIFVTALYLTKSSRLTYSHASRAALFNPLGVISPSLGNHTLNYDPEARESSKKLYELLSDFNTAYYDDENMILGSNLFSKNTYSRQPYVANGYIGSRIPNIGFGYALDTLNFYTDAPGALNNGWPLRNHRFAGAFVSDFYCLQPKLNSTNFPELDDVGYSTVISSIPQWTNLQFSLVNDSKWFNPQNVTLDDVTNYSQNLSMKDGIVTTELDWLNSQIHVKSEIWAHRHIHPLGVVSLEIS-LNTDHLPSDFDSLDVNIWDILDFNTSHRTVLHSTGTDEKNNAVFMIVQPDNVPSS--NCAIYSTCTVKYENSTNPINSSESFEEKDVSSNIYNVILTEDQPKIIVHKYVGIMSTEFNKNKEQQDNTNIGLAKMIALNSKGNYEKLLSSHKRAWYDLYN-DAFIEIPS-DSLLEMTARSSLFHLLANTR---DYNVSSDRGLPVGVSGLSSDS----YGGMVFWDADIWMEPALLPFFPNVAQNMNNYRNATHSQAKLNAEKYGYPGAIYPWTSGKYANCTST---GPCVDYEYHINVDVAMASFSIYLNGHEGIDDEYLRYTTWPIIKNAAQFFTAYVKYNSSLGLYETYNLTDPDEFANHINNGAFTNAGIKTLLKWATDIGNHLGEVVDP---KWSEISKDIYIPRSSS-NITLEYSGMNSSVEIKQADVTLMVYPLGYINDESILNNAIKDLYYYSERQSASGPAMTYPVFVAAAAGLLNHGSSSQSYLYKSVLPYLRAPFAQFSEQSDDNFLTNGLTQPAFPFLTANGGFLQSILFGLTGIRYSYEVDPDTKKINRLLRFNPIELPLLPGGIAIRNFKYMNQVLDIIIDDHNGTIVHKSGDVPIHIKIPNRSLIHDQDINFYNGSENERKPNLERRDVDRVGDPMRMDRYGTYYLLKPKQELTVQLFKPGLNARNNIAENKQITNLTAGVPGDVAFSALDGNNYTHWQPLDKIHRAKLLIDLGEYNEKEITKGMILWGQRPAKNISISILPHSEKVENLFANVTEIMQNSGNDQLLNETIGQLLDNAGIPVENVIDFDGIEQEDDESLDDVQALLHWKKEDLAKLIEQIPRLNFLKRKFVKILDNVPVSPSEPYYEASRNQSLIEILPSNRTTFTIDYDKLQVGDKGNTDWRKTRYIVVAVQGVYDDYDDDNKGATIKEIVLND", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..*.. * :. . :* . :. . * . : . . :.*: . : : *. : ... .. : : : . :. : . .: . : :. . : * * * :* :: ::: . * . ::::.. . :. **. .. * * *** : ** * : * *: : ** . * :.: * * :.* *. . . * *:. : :* : . : : .*:* : . . . .: *** :::..:**. : *.:* :. . * ::. : : . . : *: * . :****. *: :*: : . : :* * *****: :*. : :. : : : * ::* . . . . ***. *****: :** *: : . : . . . : * . . .: . ", "identical_positions": 73, "similar_positions": 157, "identity": "5.93%" }, { "cls_id": "homologset.agr.SGD:S000006232", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI60-1", "uniprot_id": "REEP6_RAT", "id": "Q5XI60-1", "name": "Receptor expression-enhancing protein 6", "aln": "-----------MDGLRQRFERFLEQK-NVATDALGALEARTGVEKRYLAAGA--LTLLGLYLLFGYGASLLCNVIGFVYPAYASVKAIESPNKEDDTVWLTYWVVYALFGLVEFFSDLLLFWFPFYYAGKCAFLLFCMTPGPWNGALLLYHRVIRPLFLKHHVALDSAASQLSGRALDIAAGITRDVLQALARGRTLVTPASASESPAALEPDPKSSQTTLLKHK----------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JM62-1", "uniprot_id": "REEP6_MOUSE", "id": "Q9JM62-1", "name": "Receptor expression-enhancing protein 6", "aln": "-----------MDGLRQRFERFLEQK-NVATEALGALEARTGVEKRYLAAGA--LALLGLYLLFGYGASLLCNVIGFVYPAYASVKAIESPSKEDDTVWLTYWVVYALFGLVEFFSDLLLFWFPFYYAGKCAFLLFCMTPGPWNGALLLYHRVIRPLFLKHHMALDSAASQLSGRALDLAAGITRDVLQALARGRALVTPASTSEPPAALELDPK--------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96HR9-1", "uniprot_id": "REEP6_HUMAN", "id": "Q96HR9-1", "name": "Receptor expression-enhancing protein 6", "aln": "-----------MDGLRQRVEHFLEQR-NLVTEVLGALEAKTGVEKRYLAAGA--VTLLSLYLLFGYGASLLCNLIGFVYPAYASIKAIESPSKDDDTVWLTYWVVYALFGLAEFFSDLLLSWFPFYYVGKCAFLLFCMAPRPWNGALMLYQRVVRPLFLRHHGAVDRIMNDLSGRALDAAAGITRNVLQVLARSRAGITPVAVAGPSTPLEADLKPSQTPQPKDK----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66IF1-1", "uniprot_id": "REEP6_DANRE", "id": "Q66IF1-1", "name": "Receptor expression-enhancing protein 6", "aln": "-------MFAIFTKIKDRVEAFLNEK-NIVTDCLNKIEEKTGIKKRYLAYGA--AGVTGAFLLLGYGASLICNLIGFVYPAYFSIKAIESPGKEDDTQWLTYWVIYGFFSVGEFFSDIFLHWFPFYYVCKCLFLLWCMAPVSWNGSQVLYRHVVRPFFLKHEAAVDGMVSNISVKAMSAAENVTREVLHTLVRNRT-VGPAESEPRSLPSSAHTEPTVD----------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q60870-1", "uniprot_id": "REEP5_MOUSE", "id": "Q60870-1", "name": "Receptor expression-enhancing protein 5", "aln": "--------------MRERFDRFLHEK-NCMTDLLAKLEAKTGVNRSFIALGV--IGLVALYLVFGYGASLLCNLIGFGYPAYISMKAIESPNKDDDTQWLTYWVVYGVFSIAEFFSDLFLSWLPFYYMLKCGFLLWCMAPSPANGAEMLYRRIIRPIFLRHESQVDSVVKDVKDKAKETADAISKEVKKATVNLLGDVKKST---------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2RZ37-1", "uniprot_id": "REEP5_RAT", "id": "B2RZ37-1", "name": "Receptor expression-enhancing protein 5", "aln": "----------MSAAMRERFDRFLHEK-NCMTDLLAKLEAKTGVNRSFIALGV--IGLVALYLVFGYGASLLCNLIGFGYPAYISMKAIESPNKDDDTQWLTYWVVYGVFSIAEFFSDLFLSWFPFYYMLKCGFLLWCMAPSPSNGAELLYRRVIRPIFLKHESQVDSVVKDVKDKAKETADAISKEVKKATVNLLGDEKKST---------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00765-1", "uniprot_id": "REEP5_HUMAN", "id": "Q00765-1", "name": "Receptor expression-enhancing protein 5", "aln": "----------MSAAMRERFDRFLHEK-NCMTDLLAKLEAKTGVNRSFIALGV--IGLVALYLVFGYGASLLCNLIGFGYPAYISIKAIESPNKEDDTQWLTYWVVYGVFSIAEFFSDIFLSWFPFYYMLKCGFLLWCMAPSPSNGAELLYKRIIRPFFLKHESQMDSVVKDLKDKAKETADAITKEAKKATVNLLGEEKKST---------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PBX9-1", "uniprot_id": "REEP5_DANRE", "id": "Q6PBX9-1", "name": "Receptor expression-enhancing protein 5", "aln": "----------MAAALKQRFDNALHEK-NMVTDLLAKIEAKTGVNRSYIAYAV--IAFIAIYLVIGYGASLLCNLIGFVYPAYISIKAIESPAKDDDTKWLTYWVVYGVFSVVEFFADIFLSWFPFYFLAKCAFLVWCMAPTPSNGSIMLYTRIIRPFFLKNEAKIDNVMKDLTDKAAGAADKIKDEAKKATANIMFEEKKHY---------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9M2-1", "uniprot_id": "A1Z9M2_DROME", "id": "A1Z9M2-1", "name": "Receptor expression-enhancing protein", "aln": "---MATQVKQFLNGYKDDVSKSLRDASKPWTKVFDTVEEKTGVDRVNIFVGA--VGLCAIYLIFGWGAQLLCNIIGVLYPAYISIHAIESSTKQDDTKWLIYWVTFGIFTVIEFFSSLLTSVIPFYWLLKCAFLIWCMLPTEQNGSTIIYNKLVRPYFLKHHESVDRII----DDGMKKAAGVLKHD------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBM3-1", "uniprot_id": "Q9VBM3_DROME", "id": "Q9VBM3-1", "name": "Receptor expression-enhancing protein", "aln": "MAAQVSQVQRFFNGYKQDINRSLRDASKPWTKAFDSLEEKTGVERVNIFVGS--ILFCAFYLVFGWCAQLLCNIIGVLYPAYISIHGIESSTKQDDIRWLIYWVTFGIFTVIEFYPSLLTSMIPFYWLLKCTFLIWCMLPTERNGSTLIYHKLVRPYFLKLHDPVD-----------MMSAGVPKDD------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12402-1", "uniprot_id": "YOP1_YEAST", "id": "Q12402-1", "name": "Protein YOP1", "aln": "-------MSEYASSIHSQMKQFDTKY--SGNRILQQLENKTNLPKSYLVAGLGFAYLLLIFINVGGVGEILSNFAGFVLPAYLSLVALKTPTSTDDTQLLTYWIVFSFLSVIEFWSKAILYLIPFYWFLKTVFLIYIALPQTG-GARMIYQKIVAP--LTDRYILRDVSKTEKDEIRASVNEASKATGASVH-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q4QQW1-1", "uniprot_id": "REEP4_RAT", "id": "Q4QQW1-1", "name": "Receptor expression-enhancing protein 4", "aln": "-------------------------------------------------------------MVSWMICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEIKMAFVLWLLSPYTK-GASLLYRKFVHPSLSRHEKEIDACIVQAKERSYETMLSFGKRSLNMAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDTSAPTYQDPLYLEDQAPRRRPPIGYRPGGLQDSDTEDECWSDNEIAPQPPVRPREKPLSRSQSLRVVKRKPLVREGTSRSLKVRTRKKTIPSDLDS", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: . *. *** * .::: : : **: :..: * :.. : :***: * *::: * *: ::* :.: * . : ", "identical_positions": 17, "similar_positions": 33, "identity": "5.33%" }, { "cls_id": "homologset.agr.SGD:S000006233", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y697-1", "uniprot_id": "A0A8I5Y697_RAT", "id": "A0A8I5Y697-1", "name": "AP-1 complex subunit gamma", "aln": "-------------MALSASRPRRGEMTSLEPGSAAYLTEERMPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTY--RCRNVAKLLYMHMLGYPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTS-NSYLRKKAALCAVHVIRKVPELMEMFLPATKNLLNEKN----HGVLHTSVVLLTEMCERSPDMLAHFRK-----------------LVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRILGRNDDDSS--------EAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGVFLAAEKYAP----SKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNS---VEMHAYTVQRLYKAILGD---YSQQPL--VQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCT--VNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPS-EIVQTNGETEPAPLETK------------------------------------------------------------PPPSGPQPTSQANDLLDLLGGNDITPVIPTA-------------------------------------------PTSKPASAG-GELLDLLGDITLTGAPAAAPTPAS-----VPQITQPPFLLDGLSSQPLFNDIAPGIPSITAYSKNGLKIEFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSVVPAFNTGTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22892-1", "uniprot_id": "AP1G1_MOUSE", "id": "P22892-1", "name": "AP-1 complex subunit gamma-1", "aln": "-----------------------------------------MPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTY--RCRNVAKLLYMHMLGYPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTS-NSYLRKKAALCAVHVIRKVPELMEMFLPATKNLLNEKN----HGVLHTSVVLLTEMCERSPDMLAHFRK-----------------LVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRILGRNDDDSS--------EAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAP----SKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNS---VEMHAYTVQRLYKAILGD---YSQQPL--VQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCT--VNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPS-EIVQTNGETEPAPLETK------------------------------------------------------------PPPSGPQPTSQANDLLDLLGGNDITPVIPTA-------------------------------------------PTSKPASAG-GELLDLLGDITLTGAPAAAPTPAS-----VPQISQPPFLLDGLSSQPLFNDIAPGIPSITAYSKNGLKIEFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSVVPAFNTGTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43747-1", "uniprot_id": "AP1G1_HUMAN", "id": "O43747-1", "name": "AP-1 complex subunit gamma-1", "aln": "-----------------------------------------MPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTY--RCRNVAKLLYMHMLGYPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTS-NSYLRKKAALCAVHVIRKVPELMEMFLPATKNLLNEKN----HGVLHTSVVLLTEMCERSPDMLAHFRK-----------------LVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRILGRNDDDSS--------EAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAP----SKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNS---VEMHAYTVQRLYKAILGD---YSQQPL--VQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCT--VNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPT-EIVQTNGETEPAPLETK------------------------------------------------------------PPPSGPQPTSQANDLLDLLGGNDITPVIPTA-------------------------------------------PTSKPSSAG-GELLDLLGDINLTGAPAAAPAPAS-----VPQISQPPFLLDGLSSQPLFNDIAAGIPSITAYSKNGLKIEFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNTGTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TXY2-1", "uniprot_id": "A0AB32TXY2_DANRE", "id": "A0AB32TXY2-1", "name": "AP-1 complex subunit gamma", "aln": "-----------------------------------------MPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTY--RCRNVAKLLYMHMLGYPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQYVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTS-NSYLRKKAALCAVHVIRKVPELMEMFLPATKNLLSEKN----HGVLHTSVVLLTEMCERSPDMLSHFRK-----------------LVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRILGKGDDDSS--------EAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCDPEFKADCASGIFLAAEKYAP----SKRWHIDTIMRVLTTAGSYVRDDSVPNLIQLITNS---VEMHAYTVQRLYKALLDD---ISQQPL--VQVASWCIGEYGDLLVSGQCEEEEPIQVSEDEVLDVLEGLLVSNLSAPVTRGYSLTAIMKLSTRFSS---VNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRPALLERMPIMEKSATNGPA-EIVQTNGETDAPILDTK------------------------------------------------------------HPPNIPQPISQANDLLDLLGGNDVVPVIQTT-------------------------------------------APTKPASAG-GELLDLLGDLSLTGGPAPTPAPS------VP-MSQPPFLLDGLTSQPLFNDIGAGIPPMTAYNKNGLKIEFTFERSNPNPNIAVITIHATNTTEVDMTEFVFQAAVPKTFQLQLLSPSSNVVPALNQGSVTQVIRVLNPQKQQLRMRIKLTYTHKGSPVQDLAEVNNFPPQSWQ--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B0R024-1", "uniprot_id": "B0R024_DANRE", "id": "B0R024-1", "name": "AP-1 complex subunit gamma", "aln": "-----------------------------------------MTPSVRLQEMIRVIRSARTQGEERGIIQKECAEIRAQFRQTDNGE--RSHSLAKLLYVHMLGYPAHFGQMECVRLIASPRYSEKRIGYLGAMMLLDEKQDASLLITNSIKNDLSHSSQYVQSLALCTLACMGSSEMCRDLAPEIERLLRAS-TSYIKKKATLCAVHIIRKVPELAELFTPSARSLLSEKN----HGVLHGAVVLITELCERNAETLDKFRK-----------------AVPELVTIMKGLVTSSYSPEHNVAGISDPFLQVRILRLLRILGHNNDSAS--------DAMNDLLAQVATNTDSSKTAGSAVLYETVLTIMDINSESGLRVLAVNILGRFLLNNDRNIRYISMTSLQKIVQTDHNAVQRHRGTIVDCLKDQDTSVKRRALELSLALVSPVNIRSMMKELLIFLSSCPVELRSQTASGIFNAAERYSP----SKRWHIDTILHVLTTAGGDVRDETVPNLIQLITTA---SELHCYTVHKLYRALVKD---ISQQSL--VQVACWCIGEYGDLLLKGECEEIEPVQVTEDDVLDALETVLQSHMSAPATRGFALTATMKLSTRITDN--VDRIRSIVSIYGSCIDLELQQRAVEYNALFKKYDHMRAAVLERMPLMEKNSPGHTNGDSSGEIKEPEPAKTKPV------------------------------------------------------------EPILLSEPANQVCDLLDLLGGTDTPVQPSSA-------------------------------------------PTSTATTTSSADLLDLLGGLEPT-----------------------------------------PVPAVTVYEKNGVSLKIQCD-SQTDTDIT-VTLIASNSTQNDISNFTLQAAVPKSVQLQMKAPSGNVIAAHGLGQVTQTVLLNNPNKVSLKMRVRVSYSDQGTMLQDTVQIDSFPSPSWNSQPSIGVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O88512-1", "uniprot_id": "AP1G2_MOUSE", "id": "O88512-1", "name": "AP-1 complex subunit gamma-like 2", "aln": "----------------------------------------MVVHSLRLQDLIEEIRGAKTQAQEREVIQKECAQIRASFRDGDPLQ--RHRQLAKLLYVHMLGYPAHFGQMECLKLIASPRFTDKRVGYLGAMLLLDERHDSHLLITNSIKNDLSQGNQPVQGLALCTLSTMGSAEMCRDLAPEVEKLLLQP-SPYVRKKAILTAVHMIRKDPELSGIFLPPCTKLLRERH----HGIQLGTVTLITELCERNPAALRHFRK-----------------VVPQLVQILRTLVTTGYSTEHSISGVSDPFLQVQILRLLRILGRNHEESS--------ETMNDLLAQVATNTDTSRNAGNAVLLETVLTIMAIHSAAGLRVLAVNILGRFLLNNDKNIRYVALTSLLQLVQSDHSAVQRHRSTVVECLQETDASLSRRALELSLALVNSSNVRAMMQELQAFLESCPPDLRADCASGILLAAERFAP----SKRWHIDTILHVLTTAGAHVRDDAVANLTQLIGEA---EELHTYSVRRLYSALAED---ISQQPL--VQVAAWCIGEYGDLLLEGNCEETEPFQVEEEDVLALLEKVLQSHMSLPATRGYAITALMKLSTRLRGD--NNRIRQVVSIYGSCVDLELQQRAVEYNTLFQKYDHMRAAILEKMPLVER---GDPHVKEGGKEKQTEAQPLEVT------------------------------------------------------------APAPTEPQATKLLDLLDLLGDTSEPLSSGHA-------------------------------------------QHLPPQTPSPGEALIHLLDLPCTPPPP------------------------------------APIPSVRVFEREGLQLDLSFMRPLETPALLLVTATTTNSSKEDVTHFVCQAAVPKSFQLQLQAPSGNTIPAQGGLPITQVFRILNPNQAPLRLKLRLTYNHSGQPVQEIFEVDNLPVETWQ--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75843-1", "uniprot_id": "AP1G2_HUMAN", "id": "O75843-1", "name": "AP-1 complex subunit gamma-like 2", "aln": "----------------------------------------MVVPSLKLQDLIEEIRGAKTQAQEREVIQKECAHIRASFRDGDPVH--RHRQLAKLLYVHMLGYPAHFGQMECLKLIASSRFTDKRVGYLGAMLLLDERHDAHLLITNSIKNDLSQGIQPVQGLALCTLSTMGSAEMCRDLAPEVEKLLLQP-SPYVRKKAILTAVHMIRKVPELSSVFLPPCAQLLHERH----HGILLGTITLITELCERSPAALRHFRK-----------------VVPQLVHILRTLVTMGYSTEHSISGVSDPFLQVQILRLLRILGRNHEESS--------ETMNDLLAQVATNTDTSRNAGNAVLFETVLTIMDIRSAAGLRVLAVNILGRFLLNSDRNIRYVALTSLLRLVQSDHSAVQRHRPTVVECLRETDASLSRRALELSLALVNSSNVRAMMQELQAFLESCPPDLRADCASGILLAAERFAP----TKRWHIDTILHVLTTAGTHVRDDAVANLTQLIGGA---QELHAYSVRRLYNALAED---ISQQPL--VQVAAWCIGEYGDLLLAGNCEEIEPLQVDEEEVLALLEKVLQSHMSLPATRGYALTALMKLSTRLCGD--NNRIRQVVSIYGSCLDVELQQRAVEYDTLFRKYDHMRAAILEKMPLVER---DGPQADEEAKE-SKEAAQLSEA------------------------------------------------------------APVPTEPQASQLLDLLDLLDG-----ASGDV-------------------------------------------QHPPHLDPSPGGALVHLLDLPCVPPPP------------------------------------APIPDLKVFEREGVQLNLSFIRPPENPALLLITITATNFSEGDVTHFICQAAVPKSLQLQLQAPSGNTVPARGGLPITQLFRILNPNKAPLRLKLRLTYDHFHQSVQEIFEVNNLPVESWQ--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KVR8-1", "uniprot_id": "Q7KVR8_DROME", "id": "Q7KVR8-1", "name": "AP-1 complex subunit gamma", "aln": "MYPYYEQDWSVLPPENNRRFNPAFNMATIRQAFTEAVERVRMPTPTRLRDLIRQIRAARTAAEERAVVNKECAYIRSTFREEDSVW--RCRNIAKLLYIHMLGYPAHFGQLECLKLTASTRFTDKRIGYLGAMLLLDERQDVHLLITNCLKNDLNSSTQFVVGLALCTLGAIASPEMARDLASEVERLMKSP-NTYIRKKATLCAFRVIRRVPELMEIFLPATRSLLSEKN----HGILITGVTLITEMCENSSDTLMHFKKD-----------SGNREIVPNLVRILKNLILGGYSPEHDVSGVSDPFLQVKILRLLRILGHNDPDAS--------EAMNDILAQVATNTETSKNVGNTILYETVLSIMDIRSEGGLRVLAVNILGRFLLNSDKNIRYVALNTLLRTVHADTSAVQRHRTTILECLKDPDVSIRRRAMELSFALINAQNIRTMTKELLLFLEKADAEFKAQCSSGMILAAERYSP----TTRWHLDTQLSVLIAAGNYVRDDVVSSTIQLVSSSP--VPEQTYITNRFWESLQVANHCEDKQPL--LQVAVWAIGEYGDLFMYGANED-EFERPTESDLIAVYYKFLTSAQVSTTSKQYALVSLAKLSTRLQQC--VEEIQALITSFGSHLNVDLQQRGVEFTQLFGHYKHLRPPLLEKMPAMQISRISSQNGESGGGSFDDNSPDVIENGVEGGGGGGHSLIESNMNTLGDNTNILLDLLGSTDLSAGGAGDLVAATDLSNAVHKKNSRNANDVVAPVSNNQDLLDLLDLDLSAPSSTTTGAPAGGGGGGGIVALVGDNNQSSAANMNNMLGGLDLGGFGSGLDSSASIPTNGNDLASMLGGLGAPPAASPSLAASAPVGNLIDGHAGSLLADLNPTAASNNVVVPPQGPRLTALDKDGLLVQLVSVRGSD---CMRIYMTTTNNSDNTLDQYLLQAAVQRSFQLQMLTPSGSVLPPGG--VITQEMRVVATSNATLRMRLRIQYVLDGQQQVEQTEVSGFPEQQPAPAAAE---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12028-1", "uniprot_id": "AP1G1_YEAST", "id": "Q12028-1", "name": "AP-1 complex subunit gamma-1", "aln": "-------------------------------------------MGSSLRSFIKDVRGAKTLADERAIITKQSAKIRTKLRDDHLPHEKRRVNIQKLLYLYILGEKTHFGQVESINLIASDDFVDKRLGYLAATLLLDESEDLLTLLTNMLNNDLHHPNKYAVSLALTSLGFLSSPELARDLYPDVENIIKNSRDPFLLKKALQCAAKLIFKDVSLLEIFNIEDITKILSSHSICTHGVLLGVTKIIQSILLIGLNRKKDEDEDEDGIDYSNDILSPLSLLLRDFFIRLENMNSKNIEPGYDVQGICDPFLQCEIIYTLKLYFQVGELLNSNNVLDYKDNFCDLLTRIATNTDSTKNSGQAILYETVKTIFSLDLNQPLRVLGINILAKFLAGKDNNTKYVSLNTLLKVVPQEPTAVQRHRKFISHCLQDTDVSIRMRALELSFAILDDSNLVELVNELMKFLAKQDEDSKDLIIYTIDHLIDTFDTRVVKDESWKLDVFFNILKLVGSFINYEKINDILIIINNTSQLSDKSEFLRKMLTISLNGTSAEISEENIGWQLVLIWCIGEYGDLVLNEGNKNGADIINESSITDYLLTLQELYTATNLKIINYILTAALKLSVRFHDAKNIEKLRQLILSYTDSTDLSLQMKSNQYEIFFNQSISVKKIILETMPKFEKITEEQDNGKALSKNLISNEPVDLLS---------------------------------------------------------DLLGEDSKAESKASTGDNVKPIDILEEIFGEKND-------------------------------------------IAQVPKNANKEESINHSSAVEANSGVT------------------------------------LPLDANKIYDSSSLNVYASLLSANSGLAHLDLYFQAKS----LISDLKTFCAVPKAQKLTLGQLYPSST-INASQICKQSLKISGSGK--LKLRVKLDFHLNGSSSITNEQFDHKFDETL---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "D3ZGW2-1", "uniprot_id": "D3ZGW2_RAT", "id": "D3ZGW2-1", "name": "Junctophilin", "aln": "--------------------------------------------MSPGGKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGC--WAHGFESLGVFTGPGGHSYQGHWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQWQAGKRHGYGVRQS-------------------VPYHQAALLRSPRRTSLDSG----HSDPPTPPPPLPLPGDEGGSPASGSRGG---------------------FVLAGPGDADGASSRKRTPAAGGFFRRSLLLSGLRAGGRRSSLGS---------KRGSLRSEVSSEVGSTGPPGSEASGPPIPAPPALIEGSATEVYAGEWRADRRSGYGVSQRSNGLRYEGEWLGNRRHGYG--RTTRPDGSREEGKYKRNR-------LVHGGRVRSLLPLALRRGKVKEKVDRAVEGARRAVSAARQRQ------------EIAAARAADALLKAVAASSVAEKAVEA---ARMAKLIAQDLQPMLEAP----GRRPR--------------------QDSGGSDTEPLDEDSPGVYENGLTPSEGSPELP------------------------------SSPASSHQPWRAPPCRSPLPPGGNWGPFSSPKAWPEEWGGPGEQAEELAGYEAEDEAGMQGPG-----------------------------------------------------------------------PRDGSPLLGGCSDSSGSLRE---------------------------------------------------EEGEDEESLPQLRAPGGSE-----------------------------------------------------------------------SEPVTTPVLRGLSSRGPDAGCLTEEFEEPAATERPAQPGAANPLVVGAVALLDLSLAFLFSQLLT-----------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . . . * . . : . .* . * :: *: : . . ..* * . : : .. .. :. . . : . .: : : : . : . *. : . . . .. . . * : :: *: : . .: :.::::. :: *. .: : : .* . : . . . . : .: . : . * . :: . * :: .: : : : .. :. . : . : : ... . .. . . :. : : . : * :. : : : . : . . . * : . ", "identical_positions": 15, "similar_positions": 130, "identity": "1.46%" }, { "cls_id": "homologset.agr.SGD:S000006234", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZPW1-1", "uniprot_id": "D3ZPW1_RAT", "id": "D3ZPW1-1", "name": "Arrestin domain-containing protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLFDKVKAFVVELDGTRAGTEPVFHGGQAVAG-------------------------------------------------------------RVLLELAGAARVGALRLRARGRARAHWTESRSAG-------------------------------------------SST-AYTQSYSERVEVVNHRATLLAPDSGD---------IVMLPAGRHEFPFSFQLPIS-LVTSFEGKHGSVRYSIKATLHRP-WVPARRARKVFTVIEP--------------------------------------------------------------------------------VDIN--TPALLEPQAGAREKV-ARSWYCT--RGLVSLSAKIDRKGYTPGEVIPIFAEIDNGS-TRAVQPRAALVQTQTFMARGARKQ---------------------------------------------KCAVVASVDGEPVGPGRR-----------ALWP--GRALRIPPVGPSILHCR-VLSVDYSLKVCVDIPGSS--------------KLLLELPLVIGTVPLHPLGSRSASVGSRASFLQDWGL----------------------------------------------------------------CALMERPEAPPEYSEVVRESPQVAASQGLFSFLHDPDVTTE-------------------------------------------GPYFACLQEFRYRP---------------PPLYSEEDPNP-PSEAARPRCMTC--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D668-1", "uniprot_id": "ARRD2_MOUSE", "id": "Q9D668-1", "name": "Arrestin domain-containing protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLFDKVKAFVVEIDGARTGTEPVFHGGQAVAG-------------------------------------------------------------RVLLELAGAARVGALRLRARGRARAHWTESRSAG-------------------------------------------SST-AYTQSYSERVEVVNHRATLLAPDSGD---------IATLPAGRHEFPFSFQLPIS-LVTSFEGKHGSVRYSIKATLHRP-WVPARCARKVFTVIEP--------------------------------------------------------------------------------VDIN--TPALLEPQAGAREKV-ARSWYCT--RGLVSLSAKIDRKGYTPGEVIPIFAEIDNGS-TRAVQPRAALVQTQTFMARGARKQ---------------------------------------------KRAVVASVDGEPVGPNRR-----------ALWP--GRALRIPPVGPSILQCR-VLSVDYSLKVFVDIPGSS--------------KLLLELPLVIGTVPLHPLGSRSASVGSRASFLQDWGL----------------------------------------------------------------CTMMDRPEAPPEYSEVVRESQLVCASPGPSSLLHDLGVTTE-------------------------------------------GPYFACLQEFRYCP---------------PPLYSEEDPNP-PSEAVRPRCMTC--------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TBH0-1", "uniprot_id": "ARRD2_HUMAN", "id": "Q8TBH0-1", "name": "Arrestin domain-containing protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLFDKVKAFSVQLDGATAGVEPVFSGGQAVAG-------------------------------------------------------------RVLLELSSAARVGALRLRARGRAHVHWTESRSAG-------------------------------------------SST-AYTQSYSERVEVVSHRATLLAPDTGE---------TTTLPPGRHEFLFSFQLPPT-LVTSFEGKHGSVRYCIKATLHRP-WVPARRARKVFTVIEP--------------------------------------------------------------------------------VDIN--TPALLAPQAGAREKV-ARSWYCN--RGLVSLSAKIDRKGYTPGEVIPVFAEIDNGS-TRPVLPRAAVVQTQTFMARGARKQ---------------------------------------------KRAVVASLAGEPVGPGQR-----------ALWQ--GRALRIPPVGPSILHCR-VLHVDYALKVCVDIPGTS--------------KLLLELPLVIGTIPLHPFGSRSSSVGSHASFLLDWRL----------------------------------------------------------------GALPERPEAPPEYSEVVADTEEAALGQSPFPLPQDPDMSLE-------------------------------------------GPFFAYIQEFRYRP---------------PPLYSEEDPNP-LLGDMRPRCMTC--------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TPQ9-1", "uniprot_id": "ARRD3_MOUSE", "id": "Q7TPQ9-1", "name": "Arrestin domain-containing protein 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLGKVKSLTISFDCLNDSNVPVYSSGDTVSG-------------------------------------------------------------RVNLEVTGEIRVKSLKIHARGHAKVRWTESRNAG-------------------------------------------SNT-AYTQNYTEEVEYFNHKDILIGHERDDDNSEE---GFHTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRP-WLLPVKLKKEFTVFEH--------------------------------------------------------------------------------IDIN--TPSLLSPQAGTKEKT-LCCWFCT--SGPISLSAKIERKGYTPGESIQIFAEIENCS-SRMVVPKAAIYQTQAFYAKGKMKE---------------------------------------------VKQLVANLRGESLSSGKT-----------ETWN--GKLLKIPPVSPSILDCS-IIRVEYSLMVYVDIPGAM--------------DLLLSLPLVIGTIPLHPFGSRTSSVSSQCSMSMNWLA----------------------------------------------------------------LALPERPEAPPSYAEVVTE-EQRRNNLAPVGACDDFERALQ-------------------------------------------GPLFAYIQEFRFLP---------------PPLYSEIDPNPDQSSEDRPSCPSR--------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6TXF1-1", "uniprot_id": "ARRD3_RAT", "id": "Q6TXF1-1", "name": "Arrestin domain-containing protein 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLGKVKSLTISFDCLNDSNVPVYSSGDTVSG-------------------------------------------------------------RVNLEVTGEIRVKSLKIHARGHAKVRWTESRNAG-------------------------------------------SNT-AYTQNYTEEVEYFNHKDILIGHERDDDNCEE---GFSTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRP-WLLPVKLKKEFTVFEH--------------------------------------------------------------------------------IDIN--TPSLLSPQAGTKEKT-LCCWFCT--SGPISLSAKIERKGYTPGESIQIFAEIENCS-SRMVVPKAAIYQTQAFYAKGKMKE---------------------------------------------VKQLVANLRGESLSSGKT-----------ETWD--GKLLKIPPVSPSILDCS-IIRVEYSLMVYVDIPGAM--------------DLLLSLPLVIGTIPLHPFGSRTSSVSSQCSMNMNWLG----------------------------------------------------------------LSLPERPEAPPSYAEVVTE-EQRRNNLAPVSACDDFERALQ-------------------------------------------GPLFAYIQEFRFLP---------------PPLYSEIDPNPDQSSEDRPSCPSR--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96B67-1", "uniprot_id": "ARRD3_HUMAN", "id": "Q96B67-1", "name": "Arrestin domain-containing protein 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLGKVKSLTISFDCLNDSNVPVYSSGDTVSG-------------------------------------------------------------RVNLEVTGEIRVKSLKIHARGHAKVRWTESRNAG-------------------------------------------SNT-AYTQNYTEEVEYFNHKDILIGHERDDDNSEE---GFHTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRP-WLLPVKLKKEFTVFEH--------------------------------------------------------------------------------IDIN--TPSLLSPQAGTKEKT-LCCWFCT--SGPISLSAKIERKGYTPGESIQIFAEIENCS-SRMVVPKAAIYQTQAFYAKGKMKE---------------------------------------------VKQLVANLRGESLSSGKT-----------ETWN--GKLLKIPPVSPSILDCS-IIRVEYSLMVYVDIPGAM--------------DLFLNLPLVIGTIPLHPFGSRTSSVSSQCSMNMNWLS----------------------------------------------------------------LSLPERPEAPPSYAEVVTE-EQRRNNLAPVSACDDFERALQ-------------------------------------------GPLFAYIQEFRFLP---------------PPLYSEIDPNPDQSADDRPSCPSR--------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J1F4-1", "uniprot_id": "ARRD4_MOUSE", "id": "A0A0B4J1F4-1", "name": "Arrestin domain-containing protein 4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGEAG---ADGPRGRVKSLGLVFEDESKG---CYSSGETVAG-------------------------------------------------------------HVLLEAAEPVALRGLRLEAQGRATSAWGPSAGAR-------------------------------------------VCIGGGSPAASSEVEYLNLRLSLLEAPAGEG--------VTLLQPGKHEFPFRFQLPSEPLATSFTGKYGSIQYCVRAVLERP-QVPDQSVRRELQVVSH--------------------------------------------------------------------------------VDVN--TPPLLTPMLKTQEKM-VGCWLFT--SGPVSLSVKIERKGYCNGEAIPIYAEIENCS-SRLVVPKAAIFQTQTYLASGKTKT---------------------------------------------VRHMVANVRGNHIGSGST-----------DTWN--GKMLKIPPVTPSILDCC-IIRVDYSLAVYIHIPGAK--------------RLMLELPLVIGTIPYSGFGRRNSSVASQFSMDMCWLA----------------------------------------------------------------LALPEQPEAPPNYADVVSE-EEFSRHVPPYPQPSDCDGEAC-------------------------------------------YSMFACIQEFRFQP---------------PPLYSEVDPHPGDAQETQPVSFIL--------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCT1-1", "uniprot_id": "ARRD4_HUMAN", "id": "Q8NCT1-1", "name": "Arrestin domain-containing protein 4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGEAGCAAAVGAEGRVKSLGLVFEDERKG---CYSSGETVAG-------------------------------------------------------------HVLLEASEPVALRALRLEAQGRATAAWGPSTCPR-------------------------------------------ASASTAALAVFSEVEYLNVRLSLREPPAGEG--------IILLQPGKHEFPFRFQLPSEPLVTSFTGKYGSIQYCVRAVLERP-KVPDQSVKRELQVVSH--------------------------------------------------------------------------------VDVN--TPALLTPVLKTQEKM-VGCWFFT--SGPVSLSAKIERKGYCNGEAIPIYAEIENCS-SRLIVPKAAIFQTQTYLASGKTKT---------------------------------------------IRHMVANVRGNHIASGST-----------DTWN--GKTLKIPPVTPSILDCC-IIRVDYSLAVYIHIPGAK--------------KLMLELPLVIGTIPYNGFGSRNSSIASQFSMDMSWLT----------------------------------------------------------------LTLPEQPEAPPNYADVVSE-EEFSRHIPPYPQPPNCEGEVC-------------------------------------------CPVFACIQEFRFQP---------------PPLYSEVDPHPSDVEESQPVSFIL--------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BG60-1", "uniprot_id": "TXNIP_MOUSE", "id": "Q8BG60-1", "name": "Thioredoxin-interacting protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVMFKKIKSFEVVFND----PEKVYGSGEKVAG-------------------------------------------------------------RVIVEVCEVTRVKAVRILACGVAKVLWMQG-----------------------------------------------------SQQCKQTLDYLRYEDTLLLEEQPTAGENE---MVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGCVDYWVKAFLDRP-SQPTQEAKKNFEVMDL--------------------------------------------------------------------------------VDVN--TPDLMAPVSAKKEKK-VSCMFIP--DGRVSVSARIDRKGFCEGDDISIHADFENTC-SRIVVPKAAIVARHTYLANGQTKV---------------------------------------------FTQKLSSVRGNHIISGTC-----------ASWR--GKSLRVQKIRPSILGCN-ILKVEYSLLIYVSVPGSK--------------KVILDLPLVIGSR--SGLSSRTSSMASRTSSEMSWID----------------------------------------------------------------LNIPDTPEAPPCYMDIIPEDHRLESPTTP--LLDDVDDSQD-------------------------------------------SPIFMYAPEFQFMP---------------PPTYTEVDPCVLNNNNNNNNVQ----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M7W1-1", "uniprot_id": "TXNIP_RAT", "id": "Q5M7W1-1", "name": "Thioredoxin-interacting protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVMFKKIKSFEVVFND----PEKVYGSGEKVAG-------------------------------------------------------------RVTVEVCEVTRVKAVRILACGVAKVLWMQG-----------------------------------------------------SQQCKQTLDYLRYEDTLLLEDQPT-GENE---MVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGCVDYWVKAFLDRP-SQPTQEAKKNFEVMDL--------------------------------------------------------------------------------VDVN--TPDLMAPVSAKKEKK-VSCMFIP--DGRVSVSARIDRKGFCEGDDISIHADFENTC-SRIVVPKAAIVARHTYLANGQTKV---------------------------------------------LTQKLSSVRGNHIISGTC-----------ASWR--GKSLRVQKIRPSILGCN-ILRVEYSLLIYVSVPGSK--------------KVILDLPLVIGSR--SGLSSRTSSMASRTSSEMSWID----------------------------------------------------------------LNIPDTPEAPPCYMDVIPEDHRLESPTTP--LLDDVDDSQD-------------------------------------------SPIFMYAPEFQFMP---------------PPTYTEVDPCVLNNNNNN--VQ----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H3M7-1", "uniprot_id": "TXNIP_HUMAN", "id": "Q9H3M7-1", "name": "Thioredoxin-interacting protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVMFKKIKSFEVVFND----PEKVYGSGEKVAG-------------------------------------------------------------RVIVEVCEVTRVKAVRILACGVAKVLWMQG-----------------------------------------------------SQQCKQTSEYLRYEDTLLLEDQPT-GENE---MVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGCVDYWVKAFLDRP-SQPTQETKKNFEVVDL--------------------------------------------------------------------------------VDVN--TPDLMAPVSAKKEKK-VSCMFIP--DGRVSVSARIDRKGFCEGDEISIHADFENTC-SRIVVPKAAIVARHTYLANGQTKV---------------------------------------------LTQKLSSVRGNHIISGTC-----------ASWR--GKSLRVQKIRPSILGCN-ILRVEYSLLIYVSVPGSK--------------KVILDLPLVIGSR--SGLSSRTSSMASRTSSEMSWVD----------------------------------------------------------------LNIPDTPEAPPCYMDVIPEDHRLESPTTP--LLDDMDGSQD-------------------------------------------SPIFMYAPEFKFMP---------------PPTYTEVDPCILNNNVQ---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99KN1-1", "uniprot_id": "ARRD1_MOUSE", "id": "Q99KN1-1", "name": "Arrestin domain-containing protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGRVQLFEIRLSQ----GRVVYGPGEPLAG-------------------------------------------------------------TVHLRLGAPLPFRAIRVTCMGSCGVSTKAN-----------------------------------------------------DGAWVVEESYFNSSLSLADK--------------GSLPAGEHNFPFQFLLPAT-APTSFEGPFGKIVHQVRASIDTPRFSKDHKCSLVFYILSP--------------------------------------------------------------------------------LNLNS-IPDIEQPNVASTTKK-FSYKLVK--TGNVVLTASTDLRGYVVGQVLRLQADIENQS-GKDTSPVVASLLQKVSYKAKRWIY---------------------------------------------DVRTIAEVEGTGVKAWRR-----------AQWQ--EQILVPALPQSALPGCS-LIHIDYYLQVSMKAP-----------------EATVTLPLFVGNIAVNQTPLSPCP---GRESSPG-------------------------------------------------------------------TLSLVVPSAPPQE--EAEAVASGPHFSDPVSLSTKSHSQQQPLSAPLGSVSVT----TTEPWVQVGSP--ARHSLHP-PLCISIGATVPYFAEGSAGP---------------VPTTSALILPPEYSSWGYPYEAPPSYEQSCGAAGTDLGLIPGS-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0BNL6-1", "uniprot_id": "ARRD1_RAT", "id": "B0BNL6-1", "name": "Arrestin domain-containing protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGRVQLFEIRLSQ----GRVVYSPGEPLAG-------------------------------------------------------------AVHLRLGAPLPFRAIRVTCMGSCGVSNKAN-----------------------------------------------------DGAWVVEESYFNSSLSLADK--------------GSLPPGEHNFPFQFLLPAT-APTSFEGPFGKIVHQVRASIDTPRFSKDHKCSLVFYILSP--------------------------------------------------------------------------------LNLNS-IPDIEQPNVASTTKK-FSYKLVK--TGSVVLTASTDLRGYVVGQVLRLQADIENQS-GKDTSPVVASLLQKVSYKAKRWIY---------------------------------------------DVRTIAEVEGTGVKAWRH-----------AQWQ--EQILVPALPQSALPGCS-LIHIDYYLQVSMKAP-----------------EATVTLPLFVGNIAVNQTPLSPCP---GPGSSPG-------------------------------------------------------------------LLSPVVPSAPPQE--EAEAVASGPHFSDPVSLSTKSHSQQQPLSTTLGSVSVT----TIEPCVQVGSP--ARHSLHP-PLCISIGATVPYFAEGSGGP---------------VPTTSALILPPEYSSWGYPYEAPPSYEQSCGAGGTDVGLIPGS-------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N5I2-1", "uniprot_id": "ARRD1_HUMAN", "id": "Q8N5I2-1", "name": "Arrestin domain-containing protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGRVQLFEISLSH----GRVVYSPGEPLAG-------------------------------------------------------------TVRVRLGAPLPFRAIRVTCIGSCGVSNKAN-----------------------------------------------------DTAWVVEEGYFNSSLSLADK--------------GSLPAGEHSFPFQFLLPAT-APTSFEGPFGKIVHQVRAAIHTPRFSKDHKCSLVFYILSP--------------------------------------------------------------------------------LNLNS-IPDIEQPNVASATKK-FSYKLVK--TGSVVLTASTDLRGYVVGQALQLHADVENQS-GKDTSPVVASLLQKVSYKAKRWIH---------------------------------------------DVRTIAEVEGAGVKAWRR-----------AQWH--EQILVPALPQSALPGCS-LIHIDYYLQVSLKAP-----------------EATVTLPVFIGNIAVNHAPVSPRP---GLGLPPG-------------------------------------------------------------------APPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLATLSSVPG-----APEPCPQDGSP--ASHPLHP-PLCISTGATVPYFAEGSGGP---------------VPTTSTLILPPEYSSWGYPYEAPPSYEQSCG--GVEPSLTPES-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A7Q5-1", "uniprot_id": "A0AB13A7Q5_DANRE", "id": "A0AB13A7Q5-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKVQEFEITFTN----NKVVYNPGESISG-------------------------------------------------------------TVRIKSSHSLQFKAIKVCCVGSCGISSKLN-----------------------------------------------------DASWMLEEKYLSSTLSVADK--------------GTLPPGEHSFPFQFLIPAS-VPTSFEGPFGKILYKIRAFIDTPRFSKDYKAQRPFYLLNV--------------------------------------------------------------------------------LNLNE-LPDIEQPSCAVTTKK-FNYLLVK--TGTLMLKAYTDLRGYTPGQVIKLSAEIHNKS-GKDTGYVMASLIQRVSYKTKRPVF---------------------------------------------DLRPIAEVEGAGVKAGKH-----------AEWR--EQIIVPPLPQSGLTGCN-LIDIEYFIQVSLKSP-----------------EAAVTLPIYIGNIAVNLTPSIPHPMAHGVPMPTGPSL----------------------------------------------------------------NPAAVVPSAPPVEEELAGQLAAGG--GDSEEIPTKSHSQQDPSGAPLSVAPYGHASGPVLPQSQQHVQ--STDGSAP-LFCLSTGATIPFFTDGNATP---------------VPTSCPLILPPEYSTWEYPHEPPPTYEESCSSNNSSFNSSMR--------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TT80-1", "uniprot_id": "A0AB32TT80_DANRE", "id": "A0AB32TT80-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKLQEFEISFDN----NKTVYSPGESLTG-------------------------------------------------------------TLKISIAQSIQCKAIKVNCQGFCGVTSKSN-----------------------------------------------------DTDWTDEEQYFSSSVSIADK--------------GTLKEGEHSFPFKFLLPAA-APTSFVGPYGQIMYRVRAFIDTPRFAKDYKIEKPFSMTNT--------------------------------------------------------------------------------LNLNE-VPGIREPSSSSVTKN-FSYMLVK--NGTVVLNAKTDMRGYIAGQIIKVSAGIENKS-DKTTGHVVASLMQKVTYNTKKQTY---------------------------------------------DLRSVAEVEGPGVKGGNK-----------SEWN--QQIIVPALPHSSLSDGN-LIQICYYIQVYLKYP-----------------EVALTLPICIGSVALDPSQPSHSQT--VAPMPAPR------------------------------------------------------------------ITPAPSPSAPESEASNLPPRPAPKPAPKPRPRSTHASPSAPPVDLYPQLPSVSNYNGEMLKSPHQEPG--SQGPVSPNAFSYAPGLSFRQRQSSSGPS---------------APPLSLSSSSQDRNQMPSSASVPPSYRSSAYPQATNSEVLDESSSKNW--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7K8-1", "uniprot_id": "Q9I7K8_DROME", "id": "Q9I7K8-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVICEIEFCN---NSQGIFYAGQLISG-------------------------------------------------------------QVVIKTEKEKSVKAVILNIKGYAETHWADTEHD--------------------------------------------PDDQSNGESFNGHVDYLATRAYLHGS------SSS---IEVLIEPGTSSYRFACQLPIT-CPSSFEGTLGRIRYLVNVRFVRP-WKFDLNFNRCFTVIKV--------------------------------------------------------------------------------MDLNSESLMLRVPSQVESQRT-FCCFPCR--SSPLSMRLSVPQSGFVPGQIVPVEVMVSNDS-GVAVEDITVKLTMVVIYYSQPPSA-----DTN------------------------------------KDRFEMVLKTGGGVSTKCR-----------QQFT--FDLKVPPTPPTCFNLCS-IIQIGYQVEAEARVKGCHG-------------GQSLHMPITIGSVPLT-KQLQKE--PRTWGEVLPPQQL-------------------------------------------------------------DAKALILIGSEQNGEALGSPNPWAADPSIAPPSYAEAKHISPD-------------------------------------------PHKFSKSKKKSQKRGVKGSQERKAETIVFSPLYAVFDLSNQVDEMTLRANEPKTDG-----GYVNEGVEKSTWL-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JQV1-1", "uniprot_id": "A8JQV1_DROME", "id": "A8JQV1-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGIICQILFHN---NTQGVFYAGQMVAG-------------------------------------------------------------QVTLSTDKAIQIKAIRLKLKGYAETHWTESKTD--------------------------------------------SNNKSTSESYNGFEKYLSSKVYLLGS------EIS---PEMALEPGTRSYNFACPIPIN-CPSSFEGTHGRIRYMVDVNIIQP-WKYDSIFSRAFTVIQV--------------------------------------------------------------------------------MDINTYNSVSQVPVQAKTEKT-FGVWPFR--SDPLTLELNLPQTGFVPGQTVPANVLIGNES-KIRVHEVKVGLSMMITYYSDLSSG-----SKC------------------------------------ERKSVAKLKADG-VLRNSR-----------KMYD--FQLMIPSTPPSCFHLCR-IIKIGYQIEVVAKVKGMHI-------------NGTLIMPVTICGVPISPSAVQYT--PQSSGPEAPEQ-----------------------------------------------------------------RALTLIEGEGAFAPAAPPYPWSEGSTLSPPNYAEAMHSHSD-------------------------------------------SEKQSESGNAQEKS--------------YKPLYPVFDLSTSTVEKSKEAALDKEE-------------KK---------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7L0-1", "uniprot_id": "Q9I7L0_DROME", "id": "Q9I7L0-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTVTCEIDFDN---NPHGTYFGGEVLTG-------------------------------------------------------------RVTLKLDKMKLVKAITLNITGYAETRWIERVT---------------------------------------------TNRRRRRRTFCGREDYIASKTFLVGS------NLS---SQVSIEAGIHTYNFVCLIPTE-CPSSFEGSHGRVRYMATVTLVRP-WKFDQSYTRCFTVLKV--------------------------------------------------------------------------------MDLNFDSPLLRVPAHSETSKT-YCCWPCR--SDPLALQLTVPQTGFVPGQNVPLSVLVTNDS-HIPVEQLLISFVMLVTYHSKPPSMP----NTT------------------------------------SERLVVNTFKGDAVQRNCK-----------KLFS--YEIRVPATPPTCFNLCG-IIQIAYQVEVEARVKGCHN-------------NEVVTIPLTIGSVPLA-QHVPIQ--PRGFVPQLNVN---------------------------------------------------------------------ELAVEEVATAPNSSSPWSVDASIPPPNYQEAVHMRST-------------------------------------------AATRSDDLDDPEPVPPN---TLSLDGGAYKPLYPVFDIPSPSAPPPTDYTQNYMAERAFVNPAMDVDKDKGTWL-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7L1-1", "uniprot_id": "Q9I7L1_DROME", "id": "Q9I7L1-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVVTCEISFDN---NKHGTFYAGQLVKG-------------------------------------------------------------CATLKCDRSKEVQAVLLKVVGYSITKWSEKSLG--------------------------------------------STKL-----YVGREDYLSSNTYLVGSEQNNTHNNT---HRLTIEAGVHSYNFTCQLPYQ-CPSSFEGRHGCIRYIVKVLLIRP-WKFDQAYTKGFTVLKM--------------------------------------------------------------------------------LDLNFDTPQLKSAAHSEGYRT-FCCGPCK--TDPLKLELHLPQAGYVPGQKIPVTIVVVNNT-AVAVSEIRLSLVMLVRYYSVSPEH------SR------------------------------------VERLIISRAKGESVLKQCT-----------RSQT--IDLPVPSTPPTCVELSN-LIQIAYQLEVEALVKSLRE-------------QQLMVMPVTVGTIPLAVSGIVVQQPPRRSAHYEGPDS--------------------------------------------------------------RRNPPDELPMVTALESLPSDLASSAADSALP-NYEESRHTQRG-------------------------------------------NINEEELHAFGSNE--------------FAPLYPVYSIPSPTPVLTANARNAGFVN---------QSFVK---------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VI00-1", "uniprot_id": "Q9VI00_DROME", "id": "Q9VI00-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSSCSFELDR----REPIYYSGETVNG-------------------------------------------------------------RAILTTTSEKSVNEVYILFEGEAKVRWDERRTRTRG-----------------------------------------GKTEHYTEYFRGKQQYLYTRTSVFGS--------------GNLPPGTHTYNFCIPLPLE-CPSSVVAQYGKIFYEVSVVIDRQ-WRFNNVFKQPLTVIQT--------------------------------------------------------------------------------YNLN-MSPQLLMPLVREDIKH-FCCWPCS--SGPVLSTLTIPFGGYAPGQKIRFTLEIDNQSSGYDLNGIELKLKQIYKFQAQTPHHK----TRE------------------------------------KEHSLNKSCQQERVLRLSK-----------KKIE--GTLAIPAVPPSSRTEG--IISVSYQVILTISTGDCHV-------------DSDFEVPIVIGTIPLIQS------------------------------------------------------------------------------AENPASAAQWIPETPDTPAGAAADLPPSYDKCKPPTFEEATNFGERFIDIDQDEHNRTD----------------------------DFIPRYPMYTNFAMPSAPP------------QPPEEFATNQPVPVLSLPHDPTAPLVGQNNTDRPTQSYGWNTNS------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VHZ9-1", "uniprot_id": "Q9VHZ9_DROME", "id": "Q9VHZ9-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPTTCVFQLDR----LNPVYNSGEYISG-------------------------------------------------------------RILLRTDKVKRVNAVYVTLEGEAKVQWSMS-----------------------------------------------GKSE--TANYSGHQQYLHSRTNVFDN--------------TLFRAGVHVYVLTLRIPPD-CPSTCKGPYGYIAYTISLTIDKP-WGFDEVFRKPIIVVQT--------------------------------------------------------------------------------LDLN-YNAEFSLPVKDENLKY-LCHWPCI--SGPICSTLTLPASGFTPLQEVPYRLEVDNQSPHYDIIGVEVSIKQHFVFLSRKPVKR----N-F------------------------------------YSKTLVKELISDRTLRLSK-----------RQYE--SSICVPMDTPRSTLNPNYIVFLHYTLQVKLKTGYFHY-------------DTDLSVPIIVGTTSLQHLRDSVHTQQPVRRTPTPERQRLIERVTPRPP------------------------------------------------TVEEDSAGEADPATDEPHRVIEDDEPPSYDSCLPPSFSFATLAGSQQTLGSNAAVVLQR----------------------------IHLPKFPGFSTLIGTAPAHGMEDSGLDMHMYRSYGSLNTDHTGRSLDTFGSLCGPLSEHVEEQEQEAEENLDVTAQVHRPIQRATVSEVENVLQDEHLF------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VI53-1", "uniprot_id": "Q9VI53_DROME", "id": "Q9VI53-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGLKGCELQLDN----PWNTYYAGQTVNG-------------------------------------------------------------QVKFTFDSPKKVRGIIIRFLGEANTEWSEEKSVTTSE----------------------------------------GKTENEVTQLKGHEEYFKIQYYLLGGKNSS---------ETELPPGTHTYPFTCALPPN-LPSSFEGEFGHVRYTIKVTLDRP-WKFDQDMKMAFTVIAP--------------------------------------------------------------------------------VDLN-LNPRVKEPFKLELEKS-FCCFCCR--SGPLAVITNIPQTGFVSGQVLPITCEVDNTS-NVNLTAVKFELRKLVTFHTNQPRS-----EKR------------------------------------ESKVIIANLSVGPVNGGES-----------RTFT--QQMEIPALPPTNLLNCG-IIALDYDLHVECEVSGPHR-------------NLTGKVPITLGTIPLAGVRPPTQFTDAPSAVQSEDPS-----------------------------------------------------------------LAPTQPVSPASPPGGDGVGGALGWNVADSTGGGSLYPNIP----------------------------------------------PPQFVETQYR----------------APTIAGRDDSEHTQMIGDGAFAPRYPTFQFNNATAPPASQ----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KGD9-1", "uniprot_id": "A0A0B4KGD9_DROME", "id": "A0A0B4KGD9-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPIECLISFDN---NPQGVYYAGQELSG-------------------------------------------------------------VVDLSVDATKRIKGIHVTVSGYAKIRWIKKGYPR----------------------------------------------DSERAMCRAYRSYLSSRSYVLGSCANN--------SSIDWPAGEYSYTFHVILPDN-LPTSFDGKYGQIHYEIITTIERA-ARHPKVFKLPFTVIQP--------------------------------------------------------------------------------LDLN-ADAIYRVPLEILDRKR-FWSFCCP--TGPLTVKFSTPYCGYAPGQKIHFVLYINNES-SIDIIECEVKLKQEVSYESHDPQHE----YR-------------------------------------YDKHLIARKQFGNVLRWSR-----------KVYR--GYLDLPSIPPTSVKPTC-PISVNYSIKIIVNPTEFHW-------------KLKLKIPLTIGSIPIMDGPEALLRFNRQQQQHQVVSQNLQMSTQQRQRDRDRDRDMNVDRERDRDRDRDRISASVQQRRISSINNNNNNHGRLVGGLLPTNSNMNMITNVSPTPTSSTPSSTPTTAALRPTAMPAILVTSDSDNPPDYIPMMPPSYEDAMALSEKFSDD--TEFLTN-----VSMSSILSAQADVTTSEPFKPR----------YPVYYDYETPTIPPETLYDESSSRLRLTLSCQDSAAPETDEDLAPNTRGGEPPSCEKK----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E8K8-1", "uniprot_id": "Q0E8K8_DROME", "id": "Q0E8K8-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRKLLKFLIIFDN----TSLLYFPGQFLSG-------------------------------------------------------------RVLIELQDETPALGLHFHVVGEGVVRNGRR-----------------------------------------------------QERTYDKENYIDFRMRLLGDVDQG--------GPAILSPGIHSFPFKLGLPLG-LPSTFLGRYGWIQFYCKAALREN-NGIIHKNHQVFIVMNP--------------------------------------------------------------------------------IDLNLEKPILAQPFTCEVEHK-LGVVCVG--GGQIKCRVSLDRGGYVPGENILVTAFISNYS-NVSIKRTKASLTETIEYLARGKVVQ----T---------------------------------------EKRELAVLVRGKIRPGAK-----------DEWH--NELYVPPLPPTNLHGCH-LIKISYDVFFVIEPKSMEK-------------EIKLQLPIVLATYPFRHSGDAVN---------------------------------------------------------------------------------ANTWPESVLKPDTHTHYPSTLPIFRPWLHEKPIEA-----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGU7-1", "uniprot_id": "Q9VGU7_DROME", "id": "Q9VGU7-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSKVNFVFDS---NPLGLYQAGQLISG-------------------------------------------------------------TAELITERPKTIRSIFITINGYGETRWQESEERVGED----------------------------------------GKTTKSLVTHTTTEVYYSTDQPVYGQAGGS---------QLELPTGKYVFPFRATIPPN-APTSFNGAHGQIKHEVTLTIDRA-VRYNNTFKQCFTVILP--------------------------------------------------------------------------------HDLN-RRLEYKEPLQRLESKS-FWWGSIFGAHKPMIMDVSTSYSAYVPGQKIHFHLVLDNQS-DVQCMDVKVRLIKNVSYRANSSGAK----EQLK-----------------------------------VTESRVADKHCGEVLKHNK-----------AKFD--EFLTVPPTTPSTQSEKD-PIRVSYTLRFIAKTFKLHGGG-----------DLVMDFPITIGTVPLLGSADDKGPGAEKSQPSGASHP------------------------------------------------------------------GSPNFQEDVSDEQFESNTFKPRYPVYPFDGKPGTNGSNGAAN---------------------------------------FPSLYPKAEEAHPATPVKFTPNPVSPAAQKSPPYTTNTPVASPPGGNFEVLGFSIPPDYKPTPSAPAASSTGGIGWK---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1NYX2-1", "uniprot_id": "A0A8M1NYX2_DANRE", "id": "A0A8M1NYX2-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQRSIKELSVRYDP--INETNTFTNGDIVEG-------------------------------------------------------------RVVLEVTKEINVENLFVKLTGDADVRWTEGSGDD-------------------------------------------ERSYSDHERYFKQKQYFIQDSSKKGQCEKNTTLVSGETYGSVIKPGSHVFPFRFQLPQQNMPPTFKGFHGWVKYIVMVKLKRSWKPTSSAQAEINFAPRN--------------------------------------------------------------------------------FGTN---DHLLQPQSGTEDKK-MKLFGSG----KMSMTVTTDKTGYMLGEIIRVSVDIDNSS--SRDIKLKYSLKQLQTFIAGRSTT--------------------------------------------HAHKDIVKETKDCIPSGGK-----------TRFV--VDIKLPHDIMVTIENCR-IIKVQYELKVYLDVSFAS--------------DPTVKFPVVIIPPLQQCPPWHDPPPPYMPPQP------------------------------------------------------------------------NLVPYPGGAAPPPAGLYPNLYDPVPPYPGTAAGTFPNP-------------------------------------------NAMLPGFHP--------------------APSAPVYDLNQSTKESFPNAPH----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGU4-1", "uniprot_id": "Q9VGU4_DROME", "id": "Q9VGU4-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MESERLRITLDS----ADRVYFAGDIIRG-------------------------------------------------------------EIWMNVNKRTKIRAIKVQVTGKGKCKWMEILRKNSN-----------------------------------------NNEYSRSLFYTSKEVYEHSETPLPDFEPRG----------LELSAGEHTFIFEVALGRQ-LPSSFKGSYGAIKYKMRVLIQRP-WTFDERHTIPFTVVKN--------------------------------------------------------------------------------MPLQPMQRSIPSSLEKQVTKT-ISLFGTR----PITLLALLPEDFAVRGEPLRICATVINNS-TTAVEKLRFTVLQYVTYYSHVPLR------VQK-----------------------------------VECIAVATKETGSVQKKTE-----------RSFA--HELLLPDGAQPTDEQMSGVITIVYELRVEAVLRGFFK-------------NLILNLPFKVYSQDPSNRQSSLRPPPPPRPNDGPPGPELGSGNLFEPALPVYPSLDSSIGSPS--------------------------------HSSQFSECSSINSITSDSSAATLSPAVGAGTGGMDMSYTSGSQSSQYGSPSARTSLRSSNVPYMPYSSSPLMVQ--SYPPPHLPAYPPPESPQYSLLALTPPPAGVVAAPPTGGAAAGGAPAYSQLPSTSASASFLQPRQAPGAHELPPSYEELFGLANAPPGTPK---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7K7-1", "uniprot_id": "Q9I7K7_DROME", "id": "Q9I7K7-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSHRCEIQLDN----PRGVYRAGDTVNG-------------------------------------------------------------HVYLTLSERALIKAICLEANGYASTAWQQPQKHKNQK-------------------------------------KNEQPVVVQSLDFDYRVDYFAKIDYFVGSEAAQP---------QIMEAGTYNYGFHVKLPKN-CPGNFEGGHGHIRYTLQVLIHSSADRPLEVLHVRQLQIFP--------------------------------------------------------------------------------QNSLSQETRSCEIQIYEQTPR-LRFWMKP-----LHLQLQIPRQGYSPGAGISVHLKLHNPE-KLTLREAVYSLVQISTYVAHLKNKPKRLETKVE-----------------------------------RQTVLSSRHELHNLPRGEL-----------QNFQHLHMLQVPQTAATLTVAGCACLQLNYEVEVLVTTQQEKR-------------LIAARMPVIIGNVTPPCPGKLLMQEPIDGTAPEPTPP---------------------------------------------------------------------VETASTLIPNFSISTTSLASNFREAEFMVATNLNKT-------------------------------------------NKHYLSGEQLDFRP-----------------RYVYYEMDQTQSEEVKSH------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12734-1", "uniprot_id": "CSR2_YEAST", "id": "Q12734-1", "name": "Transcription factor CSR2", "aln": "MQSTVPIAIASNGNKRDVVQNVSAGDEGDILQRLARNREMISTSLSPQKSSGFSGRRRSSSVRDALSSFFGTGNSPTSSMDDYSNLMNRNYSTASTAMCRGNSFPSDVGTKAYNITGSYQPDRHRNSVPYTTIDQLHTRQDTGLRRESDPVAAKQISSNNDIVRSFITHHASNSTMFINRVLSDYLADRGFIKQTPLYNKKSVLEISIATSAESVFLPTTKSDETEYLSLIHGSLNQARTQPVGSTNTAESDFLPSCPTMDTLNENNDLSLFPLHTQRTSPSNTARTGNAMDTSNSDRASPASNNNTTDADSFVASGNNNPMNNNNSPARNRHPNSHSRSLPNAWNSQMPSFSFALIFSLNKSTTLSDIKVELTSNVRVVWFNGLPPTKNVNEECYNIGSLDWTLNADNFNLFIPQGAKSPLDIVENHSNNRKLKVLQKLSMRKRRSFSNKAVLRENILNNLNASN---STNKLNAGVYVFTIPIVLASR-IPESLYYPSARVSYSLRLATKLKDEHTQLVASRPRSSSISSPQKLRSYSCSDSYEYSQIDDTIEGETYNNDKNSTGKIAFPSSWLKSAKGRLKRNNSNGRSDNNGASSSGLAMQHDSEDTINLQYPLNLVRTPPEISVTTANKPLYINKVWENCLSYEISFAQKYVPLNGEIPITIKVAPLVKSLSVKRIRVSCREKISYRSKDYQYDFDQLDPLASDPCNPYHMRYLVRKKKDRSLPLFEVASKCTSGPSIREEVVTNTVDDNLLAYTSSKENNKDIPFSESFTVKTKLKFPKYCEVDATKAASLPPYGIDLFDPIKDPTQSENTSNNGNVLGFLVGRPNRASKTVHKIPQDKNHNEVNDTNGNSNTSLQTSSNVPIQHYTRLNKPRRGLYLDSMHFKN---IQCSHKLEIVLRVSKTDSGSSKIIRHYEVIVDTPIYLISDLCNTSNIDLPTYDMATTESSKVLPPTFEEATSVSASPRSSVSYYPDDISMQQLNLSRSTSLANGYLSTLHPKTTAVSDSSNGAPIRDQQEQQARPLRTEDYALQMGNENNAYSNMDGLLSQDIFEQETAATLFKRDIVTMNFNNNIFTPRYSPRTFTNTDYNYNDNDNNDNDTEGPGPIIHPGPEPPRYDEISS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *: : . : . . . : : : . . : . : : . : . : ", "identical_positions": 1, "similar_positions": 21, "identity": "0.09%" }, { "cls_id": "homologset.agr.SGD:S000006235", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G5E8P1-1", "uniprot_id": "BRD1_MOUSE", "id": "G5E8P1-1", "name": "Bromodomain-containing protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MRRKGR-----CHRGSAARHPSSPCSIKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEIILEDDLTAQEMSECNSNKE--NSERPPVCLRTKRHKNNRVKKKNEVLPSTHGTPA-------SASALPEPKVRIVEYS-PPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIINEKRKGDCVSAVSQNMFEFLMDRFEKESYCENQKQGEQQ-----------------------SLIDEDAVCCICMDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDD-RWGHVVCALWIPEVGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGLYMKMEPVKELTG--GSATFSVRKTAYCDVHTP---------PGCTRRPLNIYGDVEMKNGVCRKESSV---------------------KTVRSTSKVRKKAKKAKKTLAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYWLLKRLSRNGAPLLRRLQSSLQSQRNTQQREND--EEMKAAKEKLKYWQRLRHDLERARLLIELLRKREKLKREQVKVEQMAMELRLTPLTVLLRSVLEQLQE---KDPAKIFAQPVSLKEVPDYLDHIKHPMDFATMRKRLEAQGYKNLHAFEEDFNLIVDNCMKYNAKDTVFYRAAVRLRDQGGVVLRQARREVESIGLEEASGMHLPERPIAAPRRPFSWEEVDR--------LLDPANRAHMSLE---------------EQLRELLDKLDLTCSMKSSGSRSKR-----------AKLLKKEIA---------------------------LLRNKLSQQHSQAPPTGAGTGG----------------FEDEAAPLAPDTAEE---------------------------------------------------------------------------------------------------------------------------------------------VLPRLETLL----------------------QPRKRSR--STCGDS-EVEEESPGKRLDTGLTNGFGGARSEQEPGGGPGRKAAPRRRCASESSICSSNS---PLCDSSFSTPK--------------------------------------------------CGRGK---------------PALVRR----HTLEDRSELISCIENGNYAKAA------------RIAAEVGQSNMWISTDAAASVLEPLKVVWAKCSGYPSYPALIIDPKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSEEKLFLVLFFDNKRSWQWLPKSKMVPLGVDETIDKLKMMEGRNSSIRKAVRIAFDRAMNHLSRVHGEPASDLSDID", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZUW8-1", "uniprot_id": "D3ZUW8_RAT", "id": "D3ZUW8-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MRRKGR-----CHRGSAARHPSSPCSIKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEIILEDDLTAQEMSECNSNKE--NSERPPVCLRTKRHKNNRVKKKNEVLPSTHGTPA-------SASALPEPKVRIVEYS-PPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIINEKRKGDCVSAVSQNMFEFLMDRFEKESYCENQKQGEHQ-----------------------SLIDEDAVCCICMDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDD-RWGHVVCALWIPEVGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGLYMKMEPVKELTG--GSTTFSVRKTAYCDVHTP---------PGCTRRPLNIYGDVEMKNGVCRKESSV---------------------KTVRSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYWLLKRLSRNGAPLLRRLQSSLQSQRNTQQREND--EEMKAAKEKLKYWQRLRHDLERARLLIELLRKREKLKREQVKVEQMAMELRLTPLTVLLRSVLEQLQE---KDPAKIFAQPVSLKEVPDYLDHIKHPMDFATMRKRLEAQGYKNLHAFEEDFNLIVDNCMKYNAKDTVFYRAAVRLRDQGGVVLRQARREVDSIGLEEASGMHLPERPIAAPRRPFSWEEVDR--------LLDPANRAHMSLE---------------EQLRELLDKLDLTCSMKSSGSRSKR-----------AKLLKKEIA---------------------------LLRNKLSQQHSQTPSIGAGTGG----------------FEDDAAPLAPDTGEEGDK-SPPKLEPSDALPLPSDPETNSEPPTLKPVELNPEQSKLFKRVTFDNESHSTCTQSALVSG--HPPEPTLASSGDVPAAAASAVAEPSSDVNRRTSVLFCKSKS-VSPPKS------AKNTETQPTSPQLGTKTFLSVVLPRLETLL----------------------QPRKRSR--STCGDS-EVEEESPGKRLDTGLTNGFGGTRSEQEPGSGPGRKAAPRRRCASESSICSSNS---PLCDSSFSTPK--------------------------------------------------CGRGK---------------PALVRR----HTLEDRSELISCIENGNYAKAA------------RIAAEVGQNSMWISTDAAASVLEPLKVVWAKCSGYPSYPALIIDPKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSEEKLFLVLFFDNKRSWQWLPKSKMVPLGVDETIDKLKMMEGRNSSIRKAVRIAFDRAMNHLSRVHGEPASDLSDID", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95696-1", "uniprot_id": "BRD1_HUMAN", "id": "O95696-1", "name": "Bromodomain-containing protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MRRKGR-----CHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEIILEDDLTAQEMSECNSNKE--NSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPA-------SASALPEPKVRIVEYS-PPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPAVSQSMFEFLMDRFEKESHCENQKQGEQQ-----------------------SLIDEDAVCCICMDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDD-RWGHVVCALWIPEVGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGLYMKMEPVKELTG--GGTTFSVRKTAYCDVHTP---------PGCTRRPLNIYGDVEMKNGVCRKESSV---------------------KTVRSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYWLLKRLSRNGAPLLRRLQSSLQSQRSSQQREND--EEMKAAKEKLKYWQRLRHDLERARLLIELLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQD---KDPARIFAQPVSLKEVPDYLDHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGGVVLRQARREVDSIGLEEASGMHLPERPAAAPRRPFSWEDVDR--------LLDPANRAHLGLE---------------EQLRELLDMLDLTCAMKSSGSRSKR-----------AKLLKKEIA---------------------------LLRNKLSQQHSQPLPTGPGLEG----------------FEEDGAALGPEAGEE---------------------------------------------------------------------------------------------------------------------------------------------VLPRLETLL----------------------QPRKRSR--STCGDS-EVEEESPGKRLDAGLTNGFGGARSEQEPGGGLGRKATPRRRCASESSISSSNS---PLCDSSFNAPK--------------------------------------------------CGRGK---------------PALVRR----HTLEDRSELISCIENGNYAKAA------------RIAAEVGQSSMWISTDAAASVLEPLKVVWAKCSGYPSYPALIIDPKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLVLFFDNKRSWQWLPKSKMVPLGIDETIDKLKMMEGRNSSIRKAVRIAFDRAMNHLSRVHGEPTSDLSDID", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B678-1", "uniprot_id": "A0ACD6B678_DANRE", "id": "A0ACD6B678-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MKRKSQ-----PLNIFTPHR-------------EPLTYAQAQRMVDLEVDGQLHRISIFDKLEIITDEDPLAQEIIKCISSKE--NAEKHLQISEYSAQIKNNNQKKNTSDSSIQGS------------ILPEPKFHTVDYN-LPVIPSRPSTYYKYEQKTVEELDQEVEYDMDEEDFAWLDLVNEKRKDEGLNLVSFDDFEFLLDRFEKESFLESQGQHTLQ-----------------------SIDDEDAVCCICMDGDCMDSNVILFCDMCNLAVHQDCYGVPYIPEGQWLCRHCLHSPTQPANCILCPNKGGAVKQTEDD-RWGHVVCALWVPEVGFSNTVFIEPIDGVSNIPPARWKLTCYLCKEKGVGACIQCHKANCYTAFHVSCAQKSGLFMKMEPIKVLTDS-GIPTFSVKKTAYCGAHTP---------NGSVKRPLAIYKDNETNYGLCQLVD-------------------------RKSSRIGFNKQKRLKKNEEAIVTTIPPLSVPSFSSERLSPILNQVSLQKKTAFGELVLSYWTLKRQSRNGVPLNRRLQTRLHPPKNSQRKQTE--EETQALKEQLKEWHQLRHDLERARILLELIRKREKLKREEVLLQQTLMEFQLTPFTVILRAVLDQLQE---KDQAHIFAEPVNIKEVPDYMDHVLHPMDFSTMSKRIEAQGYKYLDEFEADFNLITDNCMKYNGKDTFFYRAAVKLRDQGGAILRKTRRDVQRIGLDLETGLHLLEPPKIEPSVPFSWEDVDR--------LLVPANREHMSFE---------------EQLRELLEKLDMTTAMKSSPSRSRR-----------LKLLKKNIS---------------------------DVRLELSLRKALTAVKLKNAA------------------EEEVG----HIHQKGDKSVPPKLEPSVSVLPLINAESHSEPPTLKPIEPNPDKHSHQK--DGISQS---LNGDS----------HLLLEDSDINVVATSTLAEPSSPVNRRTSVLFRKSKSSTSPLRT------LKDDETLKGSSQIGTKTFLSVVIPRLETLL----------------------HTRKRPR--SASGDS--CKDELPIKRLDTELSNSFG----LSSERELSS-SSQPRQRCTSESSMSSSNS------SIALNLMK--------------------------------------------------CGKGK---------------PALIRR----NTVEDKSEIIACIESRNFAKAA------------RIAAEVNSSSIWMPSNAATVLLEPLKVVWAKCSGYPSYPALIIDPQMPRVGCQHNGVSIPMPPLNVLQIGEQMQYKSEEKLYLVLFFDNKRTWQWLHKSKMVPLGVDKTIDKIKMMEGRTSAIRKAVRTAFNRAMNHLNHVQDEPVNDFSDVD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BA66-1", "uniprot_id": "A0A8M2BA66_DANRE", "id": "A0A8M2BA66-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MRKKVR-----QNRVATPQRPSS--PIKPSRNRETLTYAEAQRMVELEIDGRVHRLSIYDKLDVIDSDDPLAQEISECTSNKE--NTEKPQQVLVRSVRLKNNQQKKSAALTNVQGSPA-------QG-RLPEPKIRMVEYN-LPAVPRRPSVYYTYMEKTLDELDEEVEYDMDEEDYAWLEMMNEKRKSDGHSQVSQNVFEFLMDRFEKESFFDSQAQGEPQ-----------------------SLIDEDAVCCICMDGECQNSNAILFCDMCNLAVHQECYGVPHIPEGRWLCRHCLNSPSQLAECIFCPNKGGALKRTDDD-RWGHVVCAIWVPEVGFTNTLFIEPIDGVANIPPARWKLTCYLCKKKGVGACIQCSKANCYTAFHVSCAQKAGLYMKMEPVKEVTES-GGTTFSVKKTAYCCPHTP---------NGFVRRPLTIYDDSKSKNGVCQKAA-------------------------HRERVKGCQK-KKNKKPESEPDTVVPTVSGPSITPKSFNTILNQVSVQKKRMFVERVLSYWMLKRQSRNGVPLIRRLQTAIQTQKDPEDDPCV--DDHQTLTDQLKDLHRLRHDLERARLLLELIRKREKLKREEMKLQQSVLEMQLTPFPIILRVALDQLQE---KDQAKIFAQPVSVTEVPDYLDHIKHPMDFSTMRKRIDGHEYQSLDEFEEDFNLIINNCLKYNAKDTYFYRAGVRMRDHGGVILRRTRRETERIGFEFPSGIHLPEPPKLELPPSFTWHDVDR--------VLNPANRAHMSKD---------------EQLKKLLEMLDLTFAMKSCPSRSKR-----------LKLLKKTIG---------------------------DVRMDMGQKTEPPSLEQNNTK------------------EEEKAPLILPQEEEGDKSLPPKLEPSDSVPLLKNSDSPCEPPTLKPMEPSPEKCPKKVKFDGETFSTSLLNGLS----------PDVLPSENNVMVATSTLTEPANIVNRRTAVLFRKSKN-TSPQKL------LNTSEPSIDCPQLGTKTFLSVVIPRLETLL----------------------QHRKRTH--SASGDSPDEEDECPIKRLDTGLSNGFS----EPKKGIIVTRPSEPRRRCASESSISSSGSGSIQENSSDVSHTK--------------------------------------------------SGKGK---------------LAMARR----NTTDDKKELLNCTEPGNISKAN------------KLAAEIDSSNIWMPANTTPLNLEPLKVVWAKLSGYPSYPALIIDPQLPRVGCHLNEEYIPTPPRDVLRVGELMQFRSKEKLFLVRFFDSKRNWQWLPKSKMVPFGMDKTLDKRKMLEGRTSGIRKAVQSAFNRAMNHLSLVQDLSAGD-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B2KF05-1", "uniprot_id": "BRPF3_MOUSE", "id": "B2KF05-1", "name": "Bromodomain and PHD finger-containing protein 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------MRKPRRKS-----RQNAEGRRSP-SPYSLKCSPTRETLTYAQAQRIVEVDIDGRLHRISIYDPLKIITEDELTAQDITECNSNKE--NSEQP-QFPAKSKKPSSKGKRKESCSKHASG----------TSFHLPQPSFRVVDTGSQPEAPPLPAAYYRYIEKPPEDLDAEVEYDMDEEDIAWLDMVNEKRRADGHSSVSADTFELLVDRLEKESYLESRSSGAQQ-----------------------SLIDEDAFCCVCLDDECHNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRCCLQSPSRPVDCVLCPNKGGAFKQTSDG-HWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICKQKGLGAAIQCHKVNCYTAFHVTCAQRAGLFMKIEPMRETSL--NGTTFTVRKTAYCEAHSP-SVAVARRKGDSPRSLSEVGDEDGPKEGGGEEEQEE-AEEEGQEGQGGVGSPLKGVSKKGKMSLKQKIKKEPEEAGREAPSITLPMVTVPQIPSYRLNKICSGLSFQRKTQFMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQREQD--EKTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQAAMELELMPFTVLLRTTLDLLQE---KDSAHIFAEPVSLSEVPDYLEFISKPMDFSTMRRKLESHLYHTLEEFEEDFNLIVTNCMKYNAKDTIFHRAAVRLRDLGGAILRHARRQAENIGYDPERGTHLPESPRLEDFYRFSWEDVDN--------ILIPENRAHLSPE---------------AQLKELLEKLDLVSTMRSSGARTRR-----------VRMLRREIN---------------------------ALRQKLAQPPPPQLLSLNKTVPNGELPAGSRGDTAVLEQAQQEEPEEEGDRDDSKLPAPPTLEPTGPAPSLSEQESPPDPPTLKPISDSKPSSRFLKSRKVEDEELLEKSALQLGSEPLQCLLSDNGIDRLSLTNPDSHPDTPLGTVGRRTSVLFKKAKNGVKLQRG-----PDGT--LENGEDHGPEDDPASPASTEDEHYS----------------------RKRPRSR---SCSDS--EGERSPQQEEETGVTNGFG-------KHTESGSDSECSLGLSGGLAFEAGSG---------LTPPK--------------------------------------------------RSRGK---------------PALSRV----PFLEGVNGDSDHS---------------------------GSGRSLLMPFEDHGDLEPLELVWAKCRGYPSYPALIIDPKMPREGLLHNGVPIPVPPLDVLKLGEQKQAEAGERLFLVLFFDNKRTWQWLPRDKVLPLGVEDTVDKLKMLEGRKTSIRKSVQVAYDRAMIHLSRVRGSHAFVTSSYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AAK8-1", "uniprot_id": "A0A8I6AAK8_RAT", "id": "A0A8I6AAK8-1", "name": "", "aln": "MGRGGDARALPWSEGGDEARESAREGAAKRGPPPAPAILFLPGPGSGAAKPRPPRALLLARPEQSSALKGPPLAHGFPLDGQAG--RPISARISASLPSSPSPSFAGARFPCEKGSDFASVCGLSSSFPVAMRKPRRKS-----RQNAEGRRSP-SPYSLKCSPTRETLTYAQAQRIVEVDMDGRLHRISIYDPLKIITEDELTAQDITECNSNKE--NSEQP-QFPAKSKKPSSKGKKKESCSKHAPG----------TSFHLPQPSFRVVDTGSQPEAPPLPAAYYRYIEKPPEDLDAEVEYDMDEEDMAWLDMVNEKRRADGHSSVSADTFELLVDRLEKESYLESRSSGAQQ-----------------------SLIDEDAFCCVCLDDECHNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRCCLQSPSRPVDCVLCPNKGGAFKQTSDG-HWAHVVCAIWIPEVCFANTVFLEPIEGIDSIPPARWKLTCYICKQKGLGAAIQCHKVNCYTAFHVTCAQRAGLFMKIEPMRETSL--NGTIFTVRKTAYCEAHSP-SVATARRKGDSPRSLSEVGDEDGLKEGGGEEEQEE-GEEEGQEGQGGVGSPLKGVSKKSKMTSKQKIKKELEEAGRETPSITVPMVTVPQIPSYRLNKICSGLSFQRKNQFMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQREHD--EKTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQAAMELELMPFTVLLRTTLDLLQE---KDPAHIFAEPVSLSEVPDYLEFISKPMDFSTMRRKLESHLYHTLEEFEEDFNLIVTNCMKYNAKDTIFHRAAVRLRDLGGAILRHARRQAENIGYDPERGTHLPESPKLEDFYRFSWEDVDN--------ILIPENRAHLSPE---------------AQLKELLEKLDLVSAMRSSGARTRR-----------VRMLRREIN---------------------------ALRQKLAQPPPPQLLSLTKTVPNGELPAGSRGDAAGLEQTLQEEPEDEGDRDDSQLPAPPTLEPTGPAPSLSEQESPPDPPTLKPISDSKPSGRLPKPRKVDDEELLGDSALQLGSEPLQCLLSDNGADRLPLTNPDSPPGTPLGNVGRRTSVLFKKAKNGVKLQRG-----PDGT--LENGE-----DAPASPASMEEEHCS----------------------RKRPRSQ---SCSDS--EGERSPQQEEETGVTNGFG-------KHTESGSDSECSLGLSGGLAFEAGSG---------LTPPK--------------------------------------------------RSRGK---------------PALSRV----PFLEGVNGDSDHS---------------------------GSGRSLLMPFEDRGDLEPLELVWAKCRGYPSYPALIIDPKMPREGLLHNGVPIPVPPLDVLRLGEQKQAEAGERLFLVLFFDNKRTWQWLPRDKVLPLGVEDTVDKLKMLEGRKTSIRKSVQVAYDRAMIHLSRVRGSHSFVTSSYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ULD4-1", "uniprot_id": "BRPF3_HUMAN", "id": "Q9ULD4-1", "name": "Bromodomain and PHD finger-containing protein 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------MRKPRRKS-----RQNAEGRRSP-SPYSLKCSPTRETLTYAQAQRIVEVDIDGRLHRISIYDPLKIITEDELTAQDITECNSNKE--NSEQP-QFPGKSKKPSSKGKKKESCSKHASG----------TSFHLPQPSFRMVDSGIQPEAPPLPAAYYRYIEKPPEDLDAEVEYDMDEEDLAWLDMVNEKRRVDGHSLVSADTFELLVDRLEKESYLESRSSGAQQ-----------------------SLIDEDAFCCVCLDDECHNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRCCLQSPSRPVDCILCPNKGGAFKQTSDG-HWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICKQKGLGAAIQCHKVNCYTAFHVTCAQRAGLFMKIEPMRETSL--NGTIFTVRKTAYCEAHSPPGAATARRKGDSPRSISETGDEEGLKEGDGEEEEEEEVEEEEQEAQGGVSGSLKGVPKKSKMSLKQKIKKEPEEAGQDTPS-TLPMLAVPQIPSYRLNKICSGLSFQRKNQFMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQREQD--EKTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQAAMELELMPFNVLLRTTLDLLQE---KDPAHIFAEPVNLSEVPDYLEFISKPMDFSTMRRKLESHLYRTLEEFEEDFNLIVTNCMKYNAKDTIFHRAAVRLRDLGGAILRHARRQAENIGYDPERGTHLPESPKLEDFYRFSWEDVDN--------ILIPENRAHLSPE---------------VQLKELLEKLDLVSAMRSSGARTRR-----------VRLLRREIN---------------------------ALRQKLAQPPPPQPPSLNKTVSNGELPAGPQGDAAVLEQALQEEPEDDGDRDDSKLPPPPTLEPTGPAPSLSEQESPPEPPTLKPINDSKPPSRFLKPRKVEEDELLEKSPLQLGNEPLQRLLSDNGINRLSLMAPDTPAGTPLSGVGRRTSVLFKKAKNGVKLQRS-----PDRV--LENGEDHGVAGSPASPASIEEERHS----------------------RKRPRSR---SCSES--EGERSPQQEEETGMTNGFG-------KHTESGSDSECSLGLSGGLAFEACSG---------LTPPK--------------------------------------------------RSRGK---------------PALSRV----PFLEGVNGDSDYN---------------------------GSGRSLLLPFEDRGDLEPLELVWAKCRGYPSYPALIIDPKMPREGLLHNGVPIPVPPLDVLKLGEQKQAEAGEKLFLVLFFDNKRTWQWLPRDKVLPLGVEDTVDKLKMLEGRKTSIRKSVQVAYDRAMIHLSRVRGPHSFVTSSYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BGP9-1", "uniprot_id": "A0A8M2BGP9_DANRE", "id": "A0A8M2BGP9-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------MRKLRKRVAQSRAGGFGRGLVREEDQDQVGPSS-----HVDMDALLCPPSPCRLNFSPTRDTLTYAQAQRMVEIELEGRLHRINICDQLSVVTEDEMLAQDLTECNSNKE--NSEQR-QGNKQAASKSKKKDGKHTAKKKSGGQYGLQGQVAHLQAPLPKPTFRKLDNFTVSDAPPLPVAYYRYMEKSGEELDNEAEYDMDEEDMAWLEMVNQKRVSDGHASVPPDTFELLIDRLERESILESRSQALSQ-----------------------STIDEDAYCCVCLDDECLNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRRCLQSPSRPVDCVLCPNRGGAFKQTSDG-SWAHVICAIWIPEVCFANTVFLEPVEGVKNIPPARWKLTCYLCKQKGRGASIQCHKANCYRAFHVTCAQRAGLYMKIDPVRETGT--NGTTFTVKKTAYCENHSP------------PGTGTEGYEDNGLVGGRGNRGQRS----------YTLGPPLQQNQNGRKKGSAAQQKKTQKNSGGGSRKTGVPLLLVPQIPSFRLNKICTGVSVERKNQFMQRLHNYWLLKRHSRNGVPLIRRLHSHLQAQK-SEQREPD--AKLQAVREELKYWQKLRQDLEKARLLIELIRKRERLKREQMKLQQAALELQLTPALVFLRATLEQLKE---KDTDHIFTTPVNLKEVPDYLEFVTVPMDFSTMHDKLEAHKYSSVADLENDFNLMVSNCLRYNSNDTVFHKAAMQLREVGGAILRHAQHQALSIGLDPSTGMHLPDKPIPHNTTVSWCDEVDM--------LLDPDNRVHMCAE---------------DQLKTLLDKLDLVASMRTSGGRTKR-----------MRLLRREIN---------------------------SLRHKISHQDRNSRLLNGKIREEKSKDAKSE---KKMDYITSEDPKKSASQKAQEPACPASSPLPGDAPPNPPLFCLETGRTTTPAQSNKPGSRKQRAKGKDRSLRENHNQTPKEDENFHTKENDSSPQEDRVCSAKNQSDSPKIGVGRRTSILFKKAKNGARPTKDKPVLLPNGVSKAQNGASQEQNTQAKAPSTPKPVSPS----------------------PHQLRSRGLSTCSDG--EGMKANSLPEENGLTNGLK-------RHNGNSSDSENST-----PAFPTHS----------SSPPK--------------------------------------------------RSRGK---------------PALSKV----PVDEEKNEVTNTN---------------------------SEAS------QNDGEMEPLTLVWAKCRGYPSYPAMIVDPKMPQEGILHNGIPIPVPPTDVLDLGKRRQEESEEKLFLVLFFDTKRTWQWLPQDKLHHMGIDDTVDRLRLMEGKKPNVRKSVHTAYDRAMTHLSHVQENSSFNPSNFI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B2RRD7-1", "uniprot_id": "BRPF1_MOUSE", "id": "B2RRD7-1", "name": "Peregrin", "aln": "------------------------------------------------------------------------MGVDFDVKTFCH--NLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDSPPPPQQTPLRKHKKKG-----RQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVSEDEEAPEEAPENGSNKE--NTETPAATPKSGKHKNKEKRKDSNHHHHS-APAS-------AAPKLPEVVYRELEQD-TPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRLEKESYFESHNKGDPN-----------------------ALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDG-RWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGA--NGTSFSVRKTAYCDIHTP---------PGSARRLPALSHSEGEEEEDEEEDEGK----------------SWSSEKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCEQVGRDSDDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKIQQIAMEMQLTPFLILLRKTLEQLQE---KDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHNLAGDEVSHHTEDVEEE-------RLVLLENQKHLPVE---------------EQLKLLLERLDEVNASKQSVGRSRR-----------AKMIKKEMT---------------------------ALRRKLAHQRETGRDGPERHGPS---------------GRGNLTPHPAACDKDGQTDSAAE---------------------------------------------------------------ESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPKTAGPPK------RPGRPPKNRESQMTPSHGGSPVGPPQLPIMGS-------------------LRQRKRGRSPRPSSSSDSDSDKSTEDPPMDLPANGFSSGNQPVKKSFLVYRNDCNLPRSSSDSESSSSSSSSAASDRTSTTPSK--------------------------------------------------QGRGK---------------PSFSRG----TFPEDSSEDTSGTENEAYSVGTGRGVGHS-----MVRKSLGRGAGWLSEDEDSP-LDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGEQSSETSDSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A411-1", "uniprot_id": "D4A411_RAT", "id": "D4A411-1", "name": "", "aln": "------------------------------------------------------------------------MGVDFDVKTFCH--NLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDSPPPPQQTPLRKHKKKG-----RQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVSEDEEAPEEAPENGSNKE--NTETPAATPKSGKHKNKEKRKDSNHHHHS-APAS-------AAPKLPEVVYRELDQD-TPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRLEKESYFESHNKGDPN-----------------------ALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDG-RWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGA--NGTSFSVRKTAYCDIHTP---------PGSARRLPALSHSEGEEEEDEEEDEGK----------------SWSSEKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKIQQIAMEMQLTPFLILLRKTLEQLQE---KDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHNLAGDEVSHHTEDVEEE-------RLVLLENQKHLPVE---------------EQLKLLLERLDEVNASKQSVGRSRR-----------AKMIKKEMT---------------------------ALRRKLAHQRETGRDGPERHGPS---------------GRGNLTPHPAACDKDGQTDSAAE---------------------------------------------------------------ESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPKTAGPPK------RPGRPPKNRESQMTPSHGGSPVGPPQLPIMGS-------------------LRQRKRGRSPRPSSSSDSDSDKSTEDPPMDLPANGFSSGNQPVKKSFLVYRNDCNLPRSSSDSESSSSSSSSAASDRTSTTPSK--------------------------------------------------QGRGK---------------PSFSRG----TFPEDSSEDTSGTENEAYSVGTGRGVGHS-----MVRKSLGRGAGWLSEDEDSP-LDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGEQSSETSDSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55201-1", "uniprot_id": "BRPF1_HUMAN", "id": "P55201-1", "name": "Peregrin", "aln": "------------------------------------------------------------------------MGVDFDVKTFCH--NLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRKHKKKG-----RQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVSEDEEAPEEAPENGSNKE--NTETPAATPKSGKHKNKEKRKDSNHHHHHNVSAS-------TTPKLPEVVYRELEQD-TPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRLEKESYFESHNKGDPN-----------------------ALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDG-RWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGA--NGTSFSVRKTAYCDIHTP---------PGSARRLPALSHSEGEEDEDEEEDEGK----------------GWSSEKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQE---KDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEE------RLVLLENQKHLPVE---------------EQLKLLLERLDEVNASKQSVGRSRR-----------AKMIKKEMT---------------------------ALRRKLAHQRETGRDGPERHGPS---------------SRGSLTPHPAACDKDGQTDSAAE---------------------------------------------------------------ESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPKTAGPPK------RPGRPPKNRESQMTPSHGGSPVGPPQLPIMSS-------------------LRQRKRGRSPRPSSSSDSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASDRTSTTPSK--------------------------------------------------QGRGK---------------PSFSRG----TFPEDSSEDTSGTENEAYSVGTGRGVGHS-----MVRKSLGRGAGWLSEDEDSP-LDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGEQSSETSDSD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7JVP4-1", "uniprot_id": "BRDH_DROME", "id": "Q7JVP4-1", "name": "Bromodomain-containing protein homolog", "aln": "------------------------------------------------------------------------MGLDFDAVEYCKGVKTQQSQPPFACPVRGCDRSYKTIMGLQYHLMKYDHDNPQPLTPVLTPSRKKARSRSGGHHSTPRPHKDHPTPGGGGAEARNGCSSASAGGGSASGVSARQYAN--PESLVSYNEEEATVTFNLDGKSVRLGIDDALPLVEDEEFAALVARGCILNADAPPLEENAP------WARVQVPVARVAEIPDYRVSDAPPRPLAYYRFIEKSLEELDGEVEYDVDEEDSAWLEHMNEERQRLGLNAVGIDTMELLMDRLEKESHFQAAANGTPTG----------------------VEVDDDAVCCICLDGECQNTNVILFCDMCNLAVHQDCYGVPYIPEGQWLCRRCLQSPSKPVNCVLCPNAGGAFKQTDHG-QWAHVVCALWIPEVRFANTVFLEPIDSIETIPPARWRLTCYVCKEKGLGACIQCHRNSCYAAFHVTCAQQAGLYMTMDTVKDGHN---DSSMHVQKFAYCHAHTP--------------------ADAKLKMNVPDFEDTR-------------------------------HKMKEARKALAKKRSTAPVVLIPTIPPDRVQEIATMVTMQRKKEFLDRIIAYWTLKRHYRNGVPLLRRLQSQGNNHGVIQRNGIEGSPDTGELYRQLKYWQCLRQDLERARLLCELVRKREKLKVAFVRISEEVVMLQLNPLEAALNKLLDALEA---RDSMQIFREPVDTSEVPDYTDIVKQPMDLGTMRAKLKECQYNSLEQLEADFDLMIQNCLAYNNKDTVFYRAGIRMRDQAAPLFVQVRKELQRDGLLARSQRYHVDHVEAEVEQELRLLLAAPASEGIVQKLLILADKSQVLKNPTYRTKKIKQIRLEISRMRKSLQKARFAARHSSHANQSQSDDEDTLGGSPSKKRTRKRFNSSGVDMELGHDDDDEEEDSDEDSMGEDTVSKDLLNSTQTPPCSPIKSLNNSSSPVGINRRTAILLTRKAQAALKRPSEPLTTPVKEEQHNSQSSNTQSTSGSSSSVTTAATAASSGAGTLNHVLSSAPPTASSFALTQNNSSGGGALASGTGIGGSSSAGTAAAASLTSTALAMNSKLSANLPVKSPKRPGRYRRVPEVRHSSSMSPKKSPNPAVTVSQALPMPETLPFERIPDSFRVYRANNQRDVSDSDDAPSQSSSPCSSCSDFSMSGSCSDFDSDEASEGDADGDPDRDGGRSRSEERDSTSQEGTTDAMDMQHASLNNVQGNNGNMAISSSSGGSGGSSSEDDELEERPLSARQNKPMKVGTRGTPTPTTMARAVALSAGRGRGKRRSNLSESTSSTATPPPLRRAGKLRSATPNASPLVNNIKARRNTTAAGSAPLTNNNRSKHSEDSASSERHNNHSHGQKPALEPLQLVWAKCRGYPWYPALILDPKTPK-GFVYNGVPLPAPPTDVLALRKN---CLDEIVFLVLFFDVKRTWQWLPANKLDILGIDKQLDQQKLVESRKPAERKAVKKAYQDALHYQSQVSDLEGQGPDPIM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6ZQF7-1", "uniprot_id": "JADE2_MOUSE", "id": "Q6ZQF7-1", "name": "E3 ubiquitin-protein ligase Jade-2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MEEKRRKYSISSDNSDTTDGHVTSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITAMKIPDSYQLSP----DDYYILADPWRQEWEKGVQVPAGAEAIPEPVVR-----LLPPLKGPPTQMSP---------DSPTLG-EGAHPDWP---GGSRYDLDEIDAYWLELLNSELKEMEKPELDELTLERVLEELETLCHQNMAQAIETQEGLG-------------------IEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGSWLCRTCALG--VQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKEC-TGTCIQCSMPSCITAFHVTCAFDRGLEMRTILA---------DNDEVKFKSLCQEHS---------------------DGGPRSEPTSE------------------------PVEPSQAVE--------DLEKVTLRKQRLQQLEENFYELVEPAEVAERLDLA--EALVDFIYQYWKLKRRANANQPLLT---PKTDEVDNLAQQEQD------VLYRRLKLFTHLRQDLERVRNLCYMVTRRERTKHTICKLQEQIFHLQMKLIEQDLCREPSGRRSKGKKNDSKRKGREGPKGSSPEKKEKVKAGPESVLGQLGLSTSFPIDGTFFNSWLAQSVQITAEDMAMSEWSLNSGHREDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPSP------------------------------------LQDGPSARTTPDKQPKKAWAQD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GKGTQGPPMRKPPRRTSSHLPSSPAAGDCPVPATLESPPPLASEILDKT---------------------------------------------------------------------------------------------------------------------------------------------APMASDLNVQVPGPTVSPKPLGRLRPPR--EMKVSRKSPGARSDAGTGLPSAVAERPKVSLHFDTEADG---------------YFSDEEMSDSEV--EAEDS----GVQRASREAGAEEVVRMGVLAS--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LGP6-1", "uniprot_id": "A0ABK0LGP6_RAT", "id": "A0ABK0LGP6-1", "name": "", "aln": "----------------------------------------------------------------------------------------MFPDLLISLKGNWDLSRHYHHSVCVCWPPCGPLTPIGRLLFVHVPPRGLLSKKLALWMEEKRRKYSISSDNSDTTDGHVTSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITAMKIPDSYQLSP----DDYYILADPWRQEWEKGVQVPAGAEAIPEPVVR-----ILPPLKGPPTLMSP---------ESPTLG-EGAHPDWP---GGSRYDLDEIDAYWLELLNSELKEMEKPELDELTLERVLEELETLCHQNMAQAIETQEGLG-------------------IEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGSWLCRTCALG--VQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKEC-TGTCIQCSTPSCLTAFHVTCAFDRGLEMRTILA---------DNDEVKFKSLCQEHS---------------------DGGPRSEPSSE------------------------PVEPSQAVE--------DLEKVTLRKQRLQQLEENFYELVEPAEVAERLDLA--EALVDFIYQYWKLKRRANANQPLLT---PKTDEVDNLAQQEQD------VLYRRLKLFTHLRQDLERVRNLCYMVTRRERTKHTICKLQEQIFHLQMKLIEQDLCREPSGRRSKGKKNDSKRKGREGPKGSSPEKKEKMKAGPESVLGQLGLSTSFPIDGTFFNSWLAQSVQITAEDMAMSEWSLNSGHREDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPPP------------------------------------LQDGPSARTTPEKPAKKAWAQD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GKGTQGPPARKPPRRTSSHLPSSPAAGDCPVPATLESPPTLASEILDET---------------------------------------------------------------------------------------------------------------------------------------------VPAASDLNVQVPGPTVSPKPLGRLRPPR--EMKVSRKSPGARSDAGTGLPSTVAERPKVSLHFDTEADG---------------YFSDEEMSDSDV--EAENR----GVQRASREAGAEEVVRMGVLAS--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQC1-1", "uniprot_id": "JADE2_HUMAN", "id": "Q9NQC1-1", "name": "E3 ubiquitin-protein ligase Jade-2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITAMKIPDSYQLSP----DDYYILADPWRQEWEKGVQVPAGAEAIPEPVVR-----ILPPLEGPPAQASP---------SSTMLG-EGSQPDWP---GGSRYDLDEIDAYWLELINSELKEMERPELDELTLERVLEELETLCHQNMARAIETQEGLG-------------------IEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGSWLCRTCALG--VQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKEC-TGTCIQCSMPSCVTAFHVTCAFDHGLEMRTILA---------DNDEVKFKSFCQEHS---------------------DGGPRNEPTSE------------------------PTEPSQAGE--------DLEKVTLRKQRLQQLEEDFYELVEPAEVAERLDLA--EALVDFIYQYWKLKRKANANQPLLT---PKTDEVDNLAQQEQD------VLYRRLKLFTHLRQDLERVRNLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCR--------------------------------------------GLSTSFPIDGTFFNSWLAQSVQITAENMAMSEWPLNNGHREDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPPPP----------------------------------PPQDGPGSRTTPDKAPKKTWGQDA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSGKGGQGPPTRKPPRRTSSHLPSSPAAGDCPILATPESPPPLAPETPDEA---------------------------------------------------------------------------------------------------------------------------------------------ASVAADSDVQVPGPAASPKPLGRLRPPR--ESKVTRRLPGARPDAGMGPPSAVAERPKVSLHFDTETDG---------------YFSDGEMSDSDV--EAEDG----GVQRGPREAGAEEVVRMGVLAS--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZPI0-1", "uniprot_id": "JADE1_MOUSE", "id": "Q6ZPI0-1", "name": "Protein Jade-1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MKRGR----LPSSSEDSDDNGSLSTTWSQHSRSQHGRSSTCSRPEDRKPSEVFRTDLITAMKLHDSYQLNP----DDYYVLADPWRQEWEKGVQVPVSPGTIPQPVAR-----VVSEE-KSLMFIRPKKYIASSGSEPPALGYVDIRTLAD---SVCRYDLNDMDAAWLEVTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLG-------------------IEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALG--VQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNEK-FGASIQCSVKNCRTAFHVTCAFDRGLEMKTILA---------ENDEVKFKSYCPKHSSH-----------RKPEEGLGEGAAQENGAPESSPQS-------------------PLEPYGSLEPNRE----EAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLP--EEVVDFLYQYWKLKRKINFNKPLIT---PKKDEEDNLAKREQD------VLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFTQYTKLLEQEKVSGVPSSCSS--ALENMLFFNSPSVGPNAPKIEDLKWHSAFFRKQMGTSLVHPLKKSHK-RDAVQNSSGTEGKTSHKQPGLCGRREGLEVS----ESLLSLEKTFA----EARLLSSAQQKNGVVTP---DHGKRRD-------------------------------------NRFHCDLVKGDLK-DKSFKQS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HKPLRSTDTSQR--HLDNTRAATSPGVGQSAPGTRKEIVPKCNGSLVKV-----------------------------------------------------------------------------------------------------------------------------------------------PITPASPVKSWGGFRIPKKGERQQQG---EAHDGACHQHSDCSHLGVSRAPAKERAKSRLRADSENDG---------------YAPDGEMSDSES-EASEKK----CIHASSTISRRTDIIRRSILAS--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZM64-1", "uniprot_id": "D3ZM64_RAT", "id": "D3ZM64-1", "name": "Protein Jade-1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MKRGR----LPSSSEDSDDNGSLSTTWSQHSRSQHGR-STCSRHEDRKPSEVFRTDLITAMKLHDSYQLNP----DEYYVLADPWRQEWEKGVQVPVSPGTIPQPVAR-----VVSEE-KSLMFIRPKKYIASSGSEPPELGYVDIRTLAD---SVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLG-------------------IEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALG--VQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNEK-FGASIQCSVKNCRTAFHVTCAFDRGLEMKTILA---------ENDEVKFKSYCPKHSSH-----------RKPEESLGEGAAQENGATECSPQS-------------------PLEPFASLEQNRE----EAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLP--EEVVDFLYQYWKLKRKINFNKPLIT---PKKDEEDNLAKREQD------VLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFSLYAKLLEQGKVSGVPSSCS---SLENMLLFNSPSVGPNVPKIEDLKWHSAFFRKQMGTNLVHSLKKSHK-RDALQNSSGTEGKTLLKQPGLSGRREGSGVP----ESLLSFEKTFA----EARLISSAQQKNGVVTP---DHGKRRD-------------------------------------NRFHCDLVKGDLK-DKSFKQS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HKPLRSTDTSQR--HLDNTRAATSPGVGQSAPGTRKEIVPKCNGSLVKV-----------------------------------------------------------------------------------------------------------------------------------------------PTTPASPVKSWGGFRIPKKGERQQQG---EAHDGACHQHSDCSHLGISRAPAKERSKSRLRTDSENDG---------------YAPDGEMSDSES-EASEKK----CIHASSTISRRTDIIRRSILAS--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6IE81-1", "uniprot_id": "JADE1_HUMAN", "id": "Q6IE81-1", "name": "Protein Jade-1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MKRGR----LPSSSEDSDDNGSLSTTWSQNSRSQHRR-SSCSRHEDRKPSEVFRTDLITAMKLHDSYQLNP----DEYYVLADPWRQEWEKGVQVPVSPGTIPQPVAR-----VVSEE-KSLMFIRPKKYIVSSGSEPPELGYVDIRTLAD---SVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLG-------------------IEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALG--VQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNEK-FGASIQCSVKNCRTAFHVTCAFDRGLEMKTILA---------ENDEVKFKSYCPKHSSH-----------RKPEESLGKGAAQENGAPECSPRN-------------------PLEPFASLEQNRE----EAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLP--EEVVDFLYQYWKLKRKVNFNKPLIT---PKKDEEDNLAKREQD------VLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFNLYTKLLEQERVSGVPSSCSSS-SLENMLLFNSPSVGPDAPKIEDLKWHSAFFRKQMGTSLVHSLKKPHK-RDPLQNSPGSEGKTLLKQPDLCGRREGMVVP----ESFLGLEKTFA----EARLIS-AQQKNGVVMP---DHGKRRD-------------------------------------NRFHCDLIKGDLK-DKSFKQS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HKPLRSTDVSQR--HLDNTRAATSPGVGQSAPGTRKEIVPKCNGSLIKVNYNQ--------------------------------------------------------------------------------------------------------------------------------------TAVKVPTTPASPVKNWGGFRIPKKGERQQQG---EAHDGACHQHSDYPYLGLGRVPAKERAKSKLKSDNENDG---------------YVPDVEMSDSES-EASEKK----CIHTSSTISRRTDIIRRSILAS--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803A0-1", "uniprot_id": "JADE1_DANRE", "id": "Q803A0-1", "name": "Protein Jade-1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MKRSR----VPSTSEDSD-NGSNSTSWSQHSNSKHRK------QSGKRPSEVFRTDLITAMKLHDSHQLNP----EDYYELADPWRQEWEKGVQVPVSPESIPQCAVR-----TVAEKSTAPLFIKPKKLIRS--SESSMLGYVGIQTLAD---GMCRYDLNEEDVAWLQITNEEFSKMGMQPLDELTMERVMEEFERRCYDNMSHAMETEEGLG-------------------IEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALG--IFPKCHLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGNPEKMEPITNVSHIPSNRWALICCLCKEK-TGACIQCSAKSCRVAFHVTCGLHCGLKMNTILT---------EADEVKFKSFCPKHSGL-----------DWNEEEGDDDRPVKVPTREDRSRN-------------------RGIDFSASSQTRLSQNPEETRLSERKLRVQQLEDEFYRFVAADEVAEHLQLP--LEMVDILFQYWKLKRKVNFNQPLIM---PKKEEEDSLARREQE------VLLRRLRLFTHLRQDLERVRNLTYMVSRRERIKRTLCRVQEQIFHHHVRLLEQGRVTGVSSTRR---LEEAMFYFRTTPPVPASP--QPLKGHCG-----QNSTLSSSEKGSNSYRSSKHIEADKPAKMLMDGVPSSG---DSVRS----ETVMSASSRRS----EGRTRSGESHRKEEESERPLEDRRRKS-------------------------------------KLWDQVSIKDKLRHAKSMEDT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSSETELDTMDDRLLLSHTNANSVATAPNMYSGSPRKTNASHQGKLVPN------------------------------------------------------------------------------------------------------------------------------------------------GTSGRHLKNWGSFRIPKRSERTSAGRQTERQEADNTADQNSSLKTFSTSPSSPQIRTRLRTGSENRR---------------HLEESDLGQSEQGKRCHTQ----RLPSPMTRRYGSDVIQRGVLAS--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6IE82-1", "uniprot_id": "JADE3_MOUSE", "id": "Q6IE82-1", "name": "Protein Jade-3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MKRHR-----PVSSSESSD-ECPSTSFTSSSMYRKKS---KNPKEQKKSAEVFRKDLISAMKIPDSHHVNP----DSYYLFTDTWKEEWEKGVQVPANPDSVPTPSLR-----IISEKVKEMLFVRPRKYIRCSSPESAEPGYINTLEQAA---STCRYDLDDMDIFWLQELNEDLGEMGYGPIDETLMEKTIEVLERHCHENMNHAIETVEGLG-------------------IEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKIPEGSWLCRSCVLG--IYPQCVLCPKKGGAMKTTRTGTKWAHVSCALWIPEVSIACPERMEPVTKISHIPPSRWALVCNLCKLK-TGACIQCSVKSCITAFHVTCAFEHGLEMKTILD---------EGDEVKFKSFCLKHSQ----------------------NKPKLGDAE-------------------------YHHHRVAEQSQA----KSEKTSLRAQKLRELEEEFYTLVQVEDVAKEMELS--AFTVDFIYNYWKLKRKSNFNKPLIP---PKEEEENGLVQPKEE------SIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSHTKVQEQIFGLQVQLINEEITEGLSLTN----ALENSLFYPPP-----------------------RITLKLKMPKSTSEDCKDSSTETEHQLSSPGSSSPGHSKRSPQMPEEPLDMNVKIYPRYPLESKSNCLQTSRSHSRCETKSSSPTPRAPSA-------------------------------------EFYHGQSLGKPLALQAALHGQV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SIGNGKNQP-NSRVSSSNGLEGNWSGNITQKVNSSEVCYDQE--SMLSSHL----------------------------------------------------------------------------------------------------------------------------------------------PSPGNIRKSSMEHFSRSFKEATNTWVKPTEDLQYCVKPTKNVSSKEQLWGRQLLRRPTGRASYQETDG---------------YCPDLEPSDSEAEGEGSKETPRVKRESSDRENPSHDSARECHGKTKTHPHSHSSMQR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M6J5-1", "uniprot_id": "F1M6J5_RAT", "id": "F1M6J5-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MMKRHR-----PVSSSESSD-ECPSTSFTSGSMYRKKS---KNPKEHKKSAEVFRKDLISAMKIPDSHHINP----DSYYLFTDTWKEEWEKGVQVPANPDSVPTPSLR-----IISEKVKEILFVRPRKYIRCSSPESAEPGYINTLELAA---STCRYDLDDMDIFWLQELNEDLGEMGYGPIDETLMEKTIEVLERHCHENMNHAIETVEGLG-------------------IEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKIPEGSWLCRSCVLG--IYPQCVLCPKKGGAMKTTRTGTKWAHVSCALWIPEVSIACPERMEPVTKISHIPPSRWALVCNLCKLK-TGACIQCSVKSCITAFHVTCAFEHGLEMKTILD---------EGDEVKFKSFCLKHSQ----------------------NKPKLGDAE-------------------------YHHHRAAEQSQA----KSEKTSLRAQKLRELEEEFYTLVQVEDVAKEMGLS--AFTVDFIYNYWKLKRKSNFNKPLIP---PKEDEQNGLVQPKEE------SIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSHTKVQEQIFGLQVQLINEEITDGLSLTN----ALENSLFYPPP-----------------------RITLKLKMPKSTSEDCRDSSTETEHQPSSPGSSSPSHSKRSPEMPEEPLDMNVKIYPRYPLESKSNCVLASRSHSQSETRSSSPTQRAPSA-------------------------------------EFYHGQTLGKPLALQAALHGQA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SIGNGKNQP-NSRLASSNGLEGNWSGNITQKVNSGEMCYDQE--SMLSSHL----------------------------------------------------------------------------------------------------------------------------------------------PSSGNIRKSGMEHFSRSFKEATNTWVKPNEDLQYCVKPTKNVSSKEQLWGRPLLRRSTGRASYQETDG---------------YCPDLEPSDSEAEGEGNKETVRVKRESSDRENPSHDSARECHGKTKTHPHSHSSMQR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92613-1", "uniprot_id": "JADE3_HUMAN", "id": "Q92613-1", "name": "Protein Jade-3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MKRHR-----PVSSSDSSD-ESPSTSFTSGSMYRIKS---KIPNEHKKPAEVFRKDLISAMKLPDSHHINP----DSYYLFADTWKEEWEKGVQVPASPDTVPQPSLR-----IIAEKVKDVLFIRPRKYIHCSSPDTTEPGYINIMELAA---SVCRYDLDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLERHCHENMNHAIETEEGLG-------------------IEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVPEGSWLCRSCVLG--IYPQCVLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLCKLK-TGACIQCSIKSCITAFHVTCAFEHGLEMKTILD---------EGDEVKFKSYCLKHSQ----------------------NRQKLGEAE-------------------------YPHHRAKEQSQA----KSEKTSLRAQKLRELEEEFYSLVRVEDVAAELGMP--TLAVDFIYNYWKLKRKSNFNKPLFP---PKEDEENGLVQPKEE------SIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSHNKIQEQIFGLQVQLLNQEIDAGLPLTN----ALENSLFYPPP-----------------------RITLKLKMPKSTPEDHRNSSTETDQQPHSPDSSSSVHSIRNMQVPQESLEMRTKSYPRYPLESKNNRLLASLSHSRSEAKESSPAWRTPSS-------------------------------------ECYHGQSLGKPLVLQAALHGQS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SIGNGKSQP-NSKFAKSNGLEGSWSGNVTQKDSSSEMFCDQE--PVFSPHL----------------------------------------------------------------------------------------------------------------------------------------------VSQGSFRKSTVEHFSRSFKETTNRWVKNTEDLQCYVKPTKNMSPKEQFWGRQVLRRSAGRAPYQENDG---------------YCPDLELSDSEAESDGNKEKVRVRKDSSDRENPPHDSRRDCHGKSKTHPLSHSSMQR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVP1-1", "uniprot_id": "JADE3_DANRE", "id": "Q7ZVP1-1", "name": "Protein Jade-3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MKRLR-----TPSSSDSSDNESPSTSFSSNKYGSKPG---TPASAQKKPAEVFRKDLISAMKLPDSHHISS----EDYYLLADTWKQEWEKGVQVLASPDTIPQPSVR-----IITEKPKEVLFSKPRKYIQCWSQDSTETGYVNIKELAE---AMCRYDLDDMDLYWLQQLNAELGMMGDGVVDELTMERVMEALERQCHENMNHAIETEEGLG-------------------IEYDEDVICDVCRSPDSEEGNDMVFCDKCNICVHQACYGIVKVPDGNWLCRTCVLG--ITPQCLLCPKTGGAMKATRAGTKWAHVSCALWIPEVSIACPERMEPITKVSHIPPSRWSLICSLCKLK-TGACIQCSVKNCTIPFHVTCAFEHSLEMKTILD---------EGDEVKFKSYCLKHS------------------------KPKAGEPG-------------------------LSPARHKPPT------ETDKLSLRAQKLQELEEEFYTYVHPEEVAHDLSLP--LHLLDFIFQYWKMKRKSNFNKALLP---PKEDEENLLLQPQED------SIHTRMRMFMHLRQDLERVRNLCYMVSRREKLKLSQSKAQEQIFNLHVKLVNQELSAGLPVSS----SIENLLFHPPP-----------------------RITLKLKMPKVQLGNGK-SSSKSGNGPLCPDNSCNLYDTSEGGIGQGKPQLHLG---RQRIEERINGILPASIYIRRDGGTPPLAVKQS-----------------------------------------------GKPLALHAALHGQS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNGKTKNEAEKSRQIKSNGILDKP---ILQRDTSCLAASEKDPRSEISGKS----------------------------------------------------------------------------------------------------------------------------------------------QSSG-FHKTSLEHFSRSLKEATVSLVR-TEDLRTFEKNSRKSSGFSKPLSTERPQ-GGGRAS-QESDG---------------YCPDAELSDSEPEAKG------KCRQGGRTQNQRGDYVKSAS-RAKHSYGSRTSVQR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12311-1", "uniprot_id": "NTO1_YEAST", "id": "Q12311-1", "name": "NuA3 HAT complex component NTO1", "aln": "------------------------------------------------------------------------------------------------------------------MNRGSLDDGPKLREEKHFQDFYPDLNADTLLPFIVPLVETKDNSTDTDSDDISNRNNREIGSVKSVQTKELIFKGRVTTEPLVLKKNEVEFQKCKITTNELKGKKNPYCVRFNESFISRYYHINKVRNRKSYKQQQKEFDG-----VEAPYFTKFSSKEAPNITISTSTKSAIQKFASISPNLVNFKPQYDMDEQDELYLHYLNKRYFKDQMS---HEIFEILMTTLETEWFHIEKHIPSTNSLIARHNILRDCKNYELYGSDDGTGLSMDQACAVCLGTDSDNLNTIVFCDGCDIAVHQECYGIIFIPEGKWLCRRCMISKNNFATCLMCPSHTGAFKQTDTG-SWVHNICALWLPELYFSNLHYMEPIEGVQNVSVSRWKLNCYICKKK-MGACIQCFQRNCFTAYHVTCARRAGLYMSKGKCTIQELASNQFSQKYSVESFCHKHAP------------RGWQTSIEGINKARKYFSLLS----------------------TLQTETPQHNEANDRTNSKFNKTIWKTPNQTPVAPHVFAEILQKVVDFFGLANPPAGAFDICKYWSMKRELTGGTPLTACFENNSLGSLTEEQVQTR-----------IDFANDQLEDLYRLKELTTLVKKRTQASNSLSRSRKKVFDIVKSPQKYLLKINVLDIFIK--SEQFKALERLVTEPKLLVILEKCKHCDFDTVQIFKEEIMHFFEVLETLPGASRILQTVSSKAKEQVTNLIGLIEHVDIKKLLSRDFIINDDKIEERPWSGPVIMEEEGLSDAEELS------------------------------------------------AGEHRMLKLILNSG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . .**::: * :*. * :* : :* . * * :* . : : * ::*** *::.*** ***: :* * **** * . * :**. **.* * . * * **:*:**: : :**: : :. ** * * :*: *:.*** .* .:**:*. .* * : * *: : . . ** :** . .* : .** : : * :: :* : . : . ", "identical_positions": 70, "similar_positions": 67, "identity": "4.39%" }, { "cls_id": "homologset.agr.SGD:S000006236", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K4K5-1", "uniprot_id": "L2GL1_RAT", "id": "Q8K4K5-1", "name": "Lethal(2) giant larvae protein homolog 1", "aln": "--------------MMKFRFRR-QGADP------------------------------------QREKLKQELFTFHKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKI--------YGAPGVEFTGLHRDAA------TVTQMHFLPGQGRLLTLLDDSSLHLWEIIQRNGCAHLEEGLSFHPPSRPSFGNASFPAGLTRVTVVLL-AAGDTVVLGTESGSIFFLDVATLALLEGQTLSPDEVLRSVPDDYRCGKALGPVESLQGHLQDPSKILIGYSRGLLVIWSQATQSVEHVFLGNQQLESLCWGR--GGSNIISSHSDGSYAIWSTDTGSPPTLQPTVVTTPYGPF--------PCKAINKILWRSCESG-DHFIIFSGGMPRASYGDRHCVSVLRAE-TLVTLDFTSRVIDFFTVHSTQPEDGFDNPQALAVLLEEELVVLDLQTPG-WPAVPAPYLAPLHSSAITCSAHVANVPSKLWARIVSAG-ERQSPQPASSALSWPITGG---RNLAQ-----EPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLSTAGLFQTDCEH-----ADSLAQAVEDDWPPFRKVGCFDPYSDDPRLG--IQKVALCKYTAQMVVAGTAGQVLVLELSDVPGEHTVSVASVDLLQDREGFTWKGHERLSPHTGPLP------------------------WPAGFQPRVLIQCL-----PPAAVTAVALHAEWSLVAFGTSHGFGLFDYQRKSPVLARCTLHPNDSLAMEGPLSRVKS-----------------------------------------------LKKSLRQSFRRIRKSRVSGKKRATTAS--SKLQEANAQLAEQTCPHDVEMTP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQRRIEPRSADDSLSGVVRCLYFADTFLRDATHH--GPTMWAGTNSGSVFAYALEVPAATAGGEKRPEQA----------VEAVLGKEVQLMHRAPVVAIAVLDGRGRPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPKVS---------------------------------------------------------------------------------AKTKFKLTAHEGCRVRKVALATFASVMSED-------------------------------------YAETCLACLTNLGDVHVFSVPGLRPQVHYSCIR----KEDISG-----------------------------IASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLDISWPQNATQPRLQESPK----------------LSQANGTRDIILAPESCEGSPSSAHSKRADTMEPPEAALSPVSIDS-AASGDTMLDTTGDVTVEYVKDFLG----------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80Y17-1", "uniprot_id": "L2GL1_MOUSE", "id": "Q80Y17-1", "name": "Lethal(2) giant larvae protein homolog 1", "aln": "--------------MMKFRFRR-QGADP------------------------------------QREKLKQELFAFHKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKI--------YGAPGVEFTGLHRDAA------TVTQMHFLPGQGRLLTLLDDSSLHLWEIIHHNGCAHLEEGLSFHPPSRPSFDNASFPASLTRVTVVLL-VAGNTAALGTESGSIFFLDVATLALLEGQTLSPDVVLRSVPDDYRCGKALGPVESLQGHLQDPSKILIGYSRGLLVIWSQATQSVDNVFLGNQQLESLCWGR--DGSSIISSHSDGSYAIWSTDTGSPPTLQPTVVTTPYGPF--------PCKAINKILWRSCESG-DHFIIFSGGMPRASYGDRHCVSVLRAE-TLVTLDFTSRVIDFFTVHSTQPEDECDNPQALAVLLEEELVVLDLQTPG-WPAVPAPYLAPLHSSAITCSAHVANVPSKLWARIVSAG-EQQSPQPASSALSWPITGG---RNLAQ-----EPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLSTAGLFQTDCEH-----ADSLAQAVEDDWPPFRKVGCFDPYSDDPRLG--IQKVALCKYTAQMVVAGTAGQVLVLELSEVPAEHAVSVANVDLLQDREGFTWKGHERLNPHTGLLP------------------------WPAGFQPRMLIQCL-----PPAAVTAVTLHAEWSLVAFGTSHGFGLFDYQRKSPVLARCTLHPNDSLAMEGPLSRVKS-----------------------------------------------LKKSLRQSFRRIRKSRVSGKKRTPAAS--SKLQEANAQLAEQTCPHDLEMTP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQRRIEPRSADDSLSGVVRCLYFADTFLRDATHH--GPTMWAGTNSGSVFAYALEVPAATAGGEKRPEQA----------VEAVLGKEVQLMHRAPVVAIAVLDGRGRPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPKVS---------------------------------------------------------------------------------AKTKFKLTAHEGCRVRKVALATFASVMSED-------------------------------------YAETCLACLTNLGDVHVFSVPGLRPQVHYSCIR----KEDISG-----------------------------IASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLDISWPQNATQPRLQESPK----------------LSQANGTRDIILAPESCEGSPSSAHSKRADTMEPPEAALSPVSIDS-AASGDTMLDTTGDVTVEYVKDFLG----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2BBF6-1", "uniprot_id": "A0A8M2BBF6_DANRE", "id": "A0A8M2BBF6-1", "name": "", "aln": "--------------MMKFRFRR-QGNDP------------------------------------HREKIKQDLFAFNKTVEHGFPNQPSALAYDPKLQLMAIGTKSGAIKI--------YGAPGVEMTGLHKDTA------AVTQIHFLCGQGRILSLLDDNTIHLWEIVQRENRSHLLEVHSFNLPGRPGIEST----SATRVTVMLLNLSCNLLALGTEGGGVHFLELPTLTLLN-KSLFQDEIMQSVPEEYKCGKSLGPVESLQEHPKDSDKILIGYSRGLVVLWDLSSRHVDNLFLGKQQLESLVWER--SGNSFVSSHSDGGYMVWAVSSSNPCTHDPVSSTIPYGPF--------PCKAVNKILWRTTESG-APLVLFSGGMPRASYGDRHCLTILQDS-SHVTLDFTSRVIDFFTIHCTDTEKDFDEPSALVVLLEEELVVIDLQMPG-WPTVPAPYLAPLHSSAITCSCHISNVPPKLWERVISAG-QQQCP--LQNYENWPICGG---KNLAP-----DPKQKELLLTGHEDGTVRFWDASGVSLKPLYKLSTASIFQTDCEH-----NDSLTQAGEEEWPPFRKVGCFDPYSDDPRLG--IQKISLCKYSGKLVVAGTAGQVIVMVLGDEKSDHMIDVATVDLLQDREGFTWKGHDRLPPKSGSVV------------------------FAPGFQPVVLVQCL-----PPAAVTAVTLHAEWNLIAFGTSHGFGLFDYHRRSPVLARCTLHPNDSLAMEGPLSRVKS-----------------------------------------------LKKSLRQSFRRIRKSRVSGKKRVVVNSPTSKVQEANAHLAD----HDAEVTP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQRRIEPRSADDSLSGVVRCLCFADTFLRDGTHH--GPTMWAGTNSGSVYAYALDVPSQ----EKFSEQS----------VEALLGKEIQLMHRAPVVSIAVLDGRGNPLPEPYEVSRDLAKAPDMQGSHSVLIASEEQFKVFMLPKVS---------------------------------------------------------------------------------AKTKFKLTAHEGCRVRKVALANFTSVSSED-------------------------------------YSENALVCLTNMGDIHMFSVPALRPQVRYDCVR----KEDISG-----------------------------IASCVFTKTGQGFYLISPSEYERFSLSARVITEPLCGVDVERPHDVSAHSSSSTTL----------------PPQANGT---------HKSQAESKSAETEDLLEEMRSVLSSPILDSPNSSADITLDTTGDLTVEDVKDFLMTVDEAENNFRNITEEDGRSAGILIN---------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3TJ91-1", "uniprot_id": "L2GL2_MOUSE", "id": "Q3TJ91-1", "name": "LLGL scribble cell polarity complex component 2", "aln": "----------------MRRFLR-TGHDP------------------------------------ARERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAVKL--------YGAPGVEFMGLHKENN------AVLQIHFLPGQCQLVTLLDDNSLHLWSLKVKGGVSELQEEESFTLRGPPGAAPS-----ATQVTEILPHSSGELLYLGTESGNVFVVQLPGFRTLHDRTICSDEVLQWLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRALSHFLSSQQLENASWQR--DGCLIVTCHSDGSHCQWPVSSDTQ-NPEPLRSSIPYGPF--------PCKAITKIFWLTTRQG-LPFTIFQGGMPRASYGDRHCISVVHNG-QQTAFDFTSRVIDFTVLSEADPAAAFDDPYALVVLAEEELVVIDLQTPG-WPPVQLPYLASLHCSAITCSHHVSNIPLKLWERIIAAG-SRQNS--HFSTMEWPIDGG---TSLAP-----PPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDP-----SENLIAQGEDEWPPLRKVGSFDPYSDDPRLG--IQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEHAVEQVEADLLQDQEGYRWKGHERLAARPGPVC------------------------FEAGFQPFVLVQCQ-----PPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKS-----------------------------------------------LKKSLRQSFRRMRRSRVSSHKRRPGGPTGEAQAQAVNIKAERTGLQNMELAP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQRKIEARSAEDSFTGFVRTLYFADTYLRDSSRH--CPSLWAGTNGGTVYAFSLRVPPA----ERRTDEP----------VRAEQAKEIQLMHRAPVVGILVLDGHNVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVS---------------------------------------------------------------------------------AKLKLKLTALEGSRVRRVGVAHFGSCRAED-------------------------------------YGEHHLAVLTNLGDIQVVSMPLLKPQVRYSCIR----REDVSG-----------------------------IASCVFTKYGQGFYLISPSEFERFSLSTKWLVEPRCLVDSTKAKKHNRPSNGNGTG----------------LKMTSSGHVRNSKSQSDGDEKKPGPVMEHALLNDAW-VLKEIQSTLEGDRRSY-GNWHPHRVAVGCRLSNGEAE-------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F3E6-1", "uniprot_id": "F7F3E6_RAT", "id": "F7F3E6-1", "name": "LLGL scribble cell polarity complex component 2", "aln": "----------------MRRFLR-TGHDP------------------------------------ARERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAVKL--------YGAPGVEFMGLHKENN------AVLQIHFLPGQCQLVTLLDDNSLHLWSLKVKGGVSELQEEESFTLRGPPGAAPS-----ATQITEILPHSSGELLYLGTESGSVFVVRLPGFCALHDRTISSDEVLQWLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLRASRVLSHFLSHQQLENVSWQR--DGCLIVTCHSDGSHCQWSVPSDTQ-SPEPLRSSVPYGPF--------PCKAITKIFWLTTRQG-LPFTIFQGGMPRASYGDRHCISVVHNG-QQTAFDFTSRVIDFTVLMEADPVAAFDDPYALVVLAEEELVVIDLQTPG-WPPVQLPYLASLHCSAITCSHHVSNIPLKLWERIIAAG-SRQNS--HFSTMEWPIDGG---TSLAP-----PPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDL-----SENLSAQGEDEWPPLRKVGSFDPYSDDPRLG--IQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEHAVEQVEADLLQDQEGYRWKGHERLAARPGPVR------------------------FEAGFQPFVLVQCQ-----PPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKS-----------------------------------------------LKKSLRQSFRRMRRSRASSHKRRPGGPTGEAQAQAVNTKAERTGLQNMELAP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQRKIEARSAEDSFTGFVRTLYFADTYLRDSSRH--CPSLWAGTNGGTVYAFSLRVPPA----ERRADEP----------VRAEQAKEIQLMHRAPVVGILVLDGHNVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVS---------------------------------------------------------------------------------AKLKLKLTALEGSRVRRVGVAHFGSCRAED-------------------------------------YGEHHLAVLTNLGDIQVVSVPLLKPQVRYSCIR----REDVSG-----------------------------IASCVFTKYGQGFYLISPSEFERFSLSTKWLVEPRCLVDSAKARNHNRPSNGNSTG----------------PKRTS-GQVRNSRSQSDGAETKPGPVMEHALLSDASGVLKEVQSTLEGDQGSC-GNWRSHRVAVGCRLSNGEAE-------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P1M3-1", "uniprot_id": "L2GL2_HUMAN", "id": "Q6P1M3-1", "name": "LLGL scribble cell polarity complex component 2", "aln": "----------------MRRFLR-PGHDP------------------------------------VRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKL--------YGAPGVEFMGLHQENN------AVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLRGPPGAAPS-----ATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQR--DGRLLVSCHSDGSYCQWPVSSEAQ-QPEPLRSLVPYGPF--------PCKAITRILWLTTRQG-LPFTIFQGGMPRASYGDRHCISVIHDG-QQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAG-WPPVQLPYLASLHCSAITCSHHVSNIPLKLWERIIAAG-SRQNA--HFSTMEWPIDGG---TSLTP-----APPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDP-----NENFSAQGEDEWPPLRKVGSFDPYSDDPRLG--IQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAARSGPVR------------------------FEPGFQPFVLVQCQ-----PPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKS-----------------------------------------------LKKSLRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSA--KAERPGLQNMELAP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRH--CPSLWAGTNGGTIYAFSLRVPPA----ERRMDEP----------VRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVS---------------------------------------------------------------------------------AKLKLKLTALEGSRVRRVSVAHFGSRRAED-------------------------------------YGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIR----REDVSG-----------------------------IASCVFTKYGQGFYLISPSEFERFSLSTKWLVEPRCLVDSAETKNH-RP--GNGAG----------------PKKAP-SRARNSGTQSDGEEKQPGLVMERALLSDER-VLKEIQSTLEGDRGS--GNWRSHRAAVGCSLSNGGAE-------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SZE3-1", "uniprot_id": "L2GL2_DANRE", "id": "Q7SZE3-1", "name": "LLGL scribble cell polarity complex component 2", "aln": "----------------MKRFRR-HGHES------------------------------------QRDKHKQDLYQFNKTVEHGFPHQPSALGFSPSLELLAIGTRSGAIKL--------YGAPGVEFMGLHDENA------AVTQVHFLPNQVELVTLLEDNSLHMWTLRAHNSMCELLEIGRFTLSGPPGAIPS-----VTRVTAVLAHSSGELLLLGTEGGHVFVVEVPGFRELEENNISVEDVQNRVPEDYVGRRNLESVETLHENPLNPRQVLIGYSRGLMVLWDLDRQRPVQHFLGTQQLESVWWME--DGESILSSHSDGSYCQWTVTGEDP-QTEPEKQETPYGAF--------PCKAISKIIQLPSKQG-PPFLIFSGGMPRASYGDRHCISVIHSK-THEALDFTSRIIDFFVIREGE--NHKGEPSALVVLVEEELVVVDLQTEG-WPVIQTPYLVPLHCSAITCSHHVSSIPLKLWERVQAAG-AHQNT--HYSRKPWPINGG---KNLAP-----DPPQRDLLLTGHEDGTVRFWDASGVCLYPMYKLSTAGVFHTDADP-----NDNMNQGSEGEWPPFRKVGCFDPYSDDPRLG--IQKIHLCKYSGYLTVAGTAGQILVLELNDEAAEQMVEATVVDLLQGQEGFRWKGQARLDVREEPVL------------------------FPPGFQPFALVQCQ-----PPAVVTAIALHSEWKLVGFGTSHGFGLYDYNQRNNIMVKCTLNPSDQMAMEGPLSRVKS-----------------------------------------------IKKSLRQSFRRIRRSRVSMRKHHTNN---AAKLQEINARLEAEALQEMELAP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQRKIEARSSDDSFTGLVRTLYFADTFVSDSSHS--TPSLWAGTNGGAVFAYVLRVPPQ----ERRAEDP----------VTAHAAKEIQLMHRAPVVGLVVLDGKGAPLPEPLEVAHDLARSPEMHGSHHLLVVSEEQFKLFTLPKVS---------------------------------------------------------------------------------SKSKLKLTAVDGSRVRRVGVAWFGS-RTDE-------------------------------------QLESCLVVLTNQGELHVISLPSIKMLVHYPCIR----REDVSG-----------------------------IASCVFTKYGQGFYLISPSEFERFSLSTRWVVQPHCLVEPPLQMRSKSPSSPVHRD----------------LPDGVPTEHRNFKGDSEGYENSARQVMEHALLNDES-VLQEIQKSLEGDQTTFLENNLKTKPKAGNVLSNGD---------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08111-1", "uniprot_id": "L2GL_DROME", "id": "P08111-1", "name": "Lethal(2) giant larvae protein", "aln": "----------------MLKFIRGKGQQPSA----------------------------------DRHRLQKDLFAYRKTAQHGFPHKPSALAYDPVLKLMAIGTQTGALKV--------FGQPGVELYGQHTLLNNSASELNVQLLEWVYGTGRILSLTAANQLILWEPVG----ATLLPIKTLPFDGK-----------LKKVSSLCCSLSKDLLWIGTEGGNIYQLDLHTF-TIKEPVIYHDVVLEQVPPAYKLNP--GAIESIRQLPNSPSKLLVAYNRGLCVLWDFESASVQRAYIAPGHGQSVGLTVNFEGSEFTWYHADGSYATWSIDNPEP---PSNVNYVPYGPD--------PCKSINRLYKGKRRSN-D-VIVFSGGMPRSAYGDHNCVSVHASDGHKVCLDFTSKVIDFFVTFENN----RDVAEVLVVLLEEELCAYDLTDPN-ICAIKAPYLHSVHASAVTCNYLASEVVQSVYESILRAG-DEQDI--DYSNISWPITGGTLPDNLEESVEEDATKLYEILLTGHEDGSVKFWDCTGVLLKPIYNFKTSSIFGSESDFRDDAAADMSAEQVDEGEPPFRKSGLFDPYSDDPRLA--VKKIAFCPKTGQLIVGGTAGQIVIADFIDLPEKVSLKYISMNLVSDRDGFVWKGHDQLNVRSNLLDGEA------------------IPTTERGVNISGVLQVL-----PPASITCMALEASWGLVSGGTAHGLVLFDFKNFVPVFHRCTLNPNDLTGAGEQLSRRKS-----------------------------------------------FKKSLRESFRKLRKGRSTRTNQSNQVP------------------TTLEARP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VERQIEARCADDGLGSMVRCLLFAKTYVTNVNIT--SPTLWSATNASTVSVFLLHLPPAQTAATAVPSASGNAPPHMPRRISAQLAKEIQLKHRAPVVGISIFDQAGSPVDQ-------LNAGENGSPPHRVLIASEEQFKVFSLPQLK---------------------------------------------------------------------------------PINKYKLTANEGARIRRIHFGSFSCRISPETLQSMHGCSPTKSTRSHGDGEADPNISGSLAVSRGDVYNETALICLTNMGDIMVLSVPELKRQLNAAAVR----REDING-----------------------------VSSLCFTNSGEALYMMSSSELQRIALATSRVVQPTGVVPVEPLENEESVLEENDAENNKETYACDEVVNTYEIKNPSGISICTRPAEENVGRNSVQQVNGVNISNSPNQANETISSSIGDITVDSVRDHLNMTTTTLCSINTEETIGRLSVLSTQTNKASTTVNMSEIPNINISNLEDLESKRNTTETSTSSVVIKSIITNISHEKTNGDNKIGTPKTAPEESQF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8K400-1", "uniprot_id": "STXB5_MOUSE", "id": "Q8K400-1", "name": "Syntaxin-binding protein 5", "aln": "--------------MRKFNIRKVLDGLTAGSSSA-------------SQQQQQQQHPPGNREPEIQETLQSEHFQLCKTVRHGFPYQPSALAFDPVQKILAVGTQTGALRL--------FGRPGVECYCQHD--SG----AAVIQLQFLINEGALVSALADDTLHLWNLRQKR--PAVLHSLKFC---------------RERVTFCHLPFQSKWLYVGTERGNIHIVNVESFTLSGYVIMWN------KAIELSSKAHPGPVVHISDNPMDEGKLLIGFESGTVVLWDLKSKKADYRYTYDEAIHSVAWHH--EGKQFICSHSDGTLTIWNVRSPAK----PVQTITPHGKQLKDGKKPEPCKPILKVELKTTRSG-EPFIILSGGLSYDTVGRRPCLTVMHGK-STAVLEMDYSIVDFLTLCETPYPNDFQEPYAVVVLLEKDLVLIDLAQNG-YPIFENPYPLSIHESPVTCCEYFADCPVDLIPALYSVG--ARQKRQGYSKKEWPINGG----NWGLG----AQSYPEIIITGHADGSVKFWDASAITLQVLYKLKTSKVFEKSRNK-----DDRQNTDIVDEDPYAIQIISWCPESRMLCIAGVSAHVIIYRFSKQEVLTEVIPMLEVRLLYEINDVDTPEG--EQPPPLSTPVGSSNPQPIPPQSHPSTSSS-SSDGLRDNVPCLKVKNSPLKQSPGYQTELVIQLVWVGGEPPQQITSLALNSSYGLVVFGNCNGIAMVDYLQKAVLLNLSTIELYGSNDPYRREPRSPR-------KSRQPSGAG---------------------------LCDITEGTVVPE-DRCKSPTSGSSSPHNSDDEQKVNNFIEKVKTQSRKFSKMVAND----------------------------------------------------LAKMSRKLSLPTDLKPD---------------------------------------------------------------------------------------------------------------------------------------------------------LDVKDNSFSRSRSSSVTSIDKESRETISALHFCETLTRKADSS-PSPCLWVGTTVGTAFVITLNLPPGP---EQRLLQP-----------VIVSPSGTILRLKGAILRMAFLDATGCLMSPAYEPWKEHNVAEEKDEKEKLKKRRPVSVSPSSSQE-----------------------------------------------------------------------------------ISENQYAVICSEKQAKVMSLPTQSCAYKQN----------------------ITETSFVLRGDIVALSNSVCLACFCANGHIMTFSLPSLRPLLDVYYLP----LTNM-----------------------------RIARTFCFANNGQALYLVSPTEIQRLTYSQETCENLQEMLGELFTPVETPEAPNRGFFKGLFGGGAQSLDREELFGESSSGKASRSLAQHIPGPGGIEGVKGAASGVVGELARARLALDERGQKLSDLEERTAAMMSSADSFSKHAHEMMLKYKDKKWYQF------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WU70-1", "uniprot_id": "STXB5_RAT", "id": "Q9WU70-1", "name": "Syntaxin-binding protein 5", "aln": "--------------MRKFNIRKVLDGLTAGSSSA-------------SQQQQQQQHPPGNREPEIQETLQSEHFQLCKTVRHGFPYQPSALAFDPVQKILAVGTQTGALRL--------FGRPGVECYCQHD--SG----AAVIQLQFLINEGALVSALADDTLHLWNLRQKR--PAVLHSLKFC---------------RERVTFCHLPFQSKWLYVGTERGNIHIVNVESFTLSGYVIMWN------KAIELSSKSHPGPVVHISDNPMDEGKLLIGFESGTVVLWDLKSKKADYRYTYDEAIHSVAWHH--EGKQFICSHSDGTLTIWNVRSPTK----PVQTITPHGKQLKDGKKPEPCKPILKVEFKTTRSG-EPFIILSGGLSYDTVGRRPCLTVMHGK-STAVLEMDYSIVDFLTLCETPYPNDFQEPYAVVVLLEKDLVLIDLAQNG-YPIFENPYPLSIHESPVTCCEYFADCPVDLIPALYSVG--ARQKRQGYSKKEWPINGG----NWGLG----AQSYPEIIITGHADGSIKFWDASAITLQVLYKLKTSKVFEKSRNK-----DDRQNTDIVDEDPYAIQIISWCPESRMLCIAGVSAHVIIYRFSKQEVVTEVIPMLEVRLLYEINDVETPEG--EQPPPLSTPVGSSTSQPIPPQSHPSTSSS-SSDGLRDNVPCLKVKNSPLKQSPGYQTELVIQLVWVGGEPPQQITSLALNSSYGLVVFGNSNGIAMVDYLQKAVLLNLSTIELYGSNDPYRREPRSPR-------KSRQPSGAG---------------------------LCDITEGTVVPE-DRCKSPTSGSSSPHNSDDEQKVNNFIEKVKTQSRKFSKMVASD----------------------------------------------------LAKMSRKLSLPTDLKPD---------------------------------------------------------------------------------------------------------------------------------------------------------LDVKDNSFSRSRSSSVTSIDKESREAISALHFCETFTRKADSS-PSPCLWVGTTVGTAFVITLNLPLGP---EQRLLQP-----------VIVSPSGTILRLKGAILRMAFLDAAGCLMPPAYEPWTEHNVPEEKDEKEKLKKRRPVSVSPSSSQE-----------------------------------------------------------------------------------ISENQYAVICSEKQAKVISLPTQNCAYKQN----------------------ITETSFVLRGDIVALSNSVCLACFCANGHIMTFSLPSLRPLLDVYYLP----LTNM-----------------------------RIARTFCFANSGQALYLVSPTEIQRLTYSQETCENLQEMLGELFTPVETPEAPNRGFFKGLFGGGAQSLDREELFGESSSGKASRSLAQHIPGPGGIEGVKGAASGVVGELARARLALDERGQKLSDLEERTAAMMSSADSFSKHAHEMMLKYKDKKWYQF------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5T5C0-1", "uniprot_id": "STXB5_HUMAN", "id": "Q5T5C0-1", "name": "Syntaxin-binding protein 5", "aln": "--------------MRKFNIRKVLDGLTAGSSSA-------------SQQQQQQ-HPPGNREPEIQETLQSEHFQLCKTVRHGFPYQPSALAFDPVQKILAVGTQTGALRL--------FGRPGVECYCQHD--SG----AAVIQLQFLINEGALVSALADDTLHLWNLRQKR--PAILHSLKFC---------------RERVTFCHLPFQSKWLYVGTERGNIHIVNVESFTLSGYVIMWN------KAIELSSKSHPGPVVHISDNPMDEGKLLIGFESGTVVLWDLKSKKADYRYTYDEAIHSVAWHH--EGKQFICSHSDGTLTIWNVRSPAK----PVQTITPHGKQLKDGKKPEPCKPILKVEFKTTRSG-EPFIILSGGLSYDTVGRRPCLTVMHGK-STAVLEMDYSIVDFLTLCETPYPNDFQEPYAVVVLLEKDLVLIDLAQNG-YPIFENPYPLSIHESPVTCCEYFADCPVDLIPALYSVG--ARQKRQGYSKKEWPINGG----NWGLG----AQSYPEIIITGHADGSVKFWDASAITLQVLYKLKTSKVFEKSRNK-----DDRPNTDIVDEDPYAIQIISWCPESRMLCIAGVSAHVIIYRFSKQEVITEVIPMLEVRLLYEINDVETPEG--EQPPPLPTPVGGSNPQPIPPQSHPSTSSS-SSDGLRDNVPCLKVKNSPLKQSPGYQTELVIQLVWVGGEPPQQITSLAVNSSYGLVVFGNCNGIAMVDYLQKAVLLNLGTIELYGSNDPYRREPRSPR-------KSRQPSGAG---------------------------LCDISEGTVVPE-DRCKSPTSGSSSPHNSDDEQKMNNFIEKVKTKSRKFSKMVAND----------------------------------------------------IAKMSRKLSLPTDLKPD---------------------------------------------------------------------------------------------------------------------------------------------------------LDVKDNSFSRSRSSSVTSIDKESREAISALHFCETFTRKTDSS-PSPCLWVGTTLGTVLVIALNLPPGG---EQRLLQP-----------VIVSPSGTILRLKGAILRMAFLDTTGCLIPPAYEPWREHNVPEEKDEKEKLKKRRPVSVSPSSSQE-----------------------------------------------------------------------------------ISENQYAVICSEKQAKVISLPTQNCAYKQN----------------------ITETSFVLRGDIVALSNSICLACFCANGHIMTFSLPSLRPLLDVYYLP----LTNM-----------------------------RIARTFCFTNNGQALYLVSPTEIQRLTYSQETCENLQEMLGELFTPVETPEAPNRGFFKGLFGGGAQSLDREELFGESSSGKASRSLAQHIPGPGGIEGVKGAASGVVGELARARLALDERGQKLGDLEERTAAMLSSAESFSKHAHEIMLKYKDKKWYQF------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AKV9-1", "uniprot_id": "A0A8M3AKV9_DANRE", "id": "A0A8M3AKV9-1", "name": "Syntaxin-binding protein 5-like", "aln": "--------------MKKFNIRKVLDGLTAVSSPS-------------PSP---QLGAKE--NELIPETLQSEHFQLCKTVRHGFPYQPSSMAFDPVQKILAIGTQSGALRL--------FGRPGVECYCQHE--SG----AAVIQLQFLINEGALVSALADDSIHLWNLRQKR--PAVLHSLKFN---------------KERITFCHLPFQSKWLYIGSERGNIHIVNVESFTLSGYTIMWN------KAIELSSKAHPGPVVHISDNPMDEGKLIIGFESGIVVLWDLKSKRADYRYTYDEAIHSVAWHH--EGKQFICSHSDGTLTIWNLKSPAK----PIQTITPHGKQPKDGKKPEPCKPILKVEYKTTRAG-DPFMIFSGGLSYDTVGRRPCLTVMHGK-STAVLEMDYPIVDFLTLCETPYPNDFQEPYAVVVLLEKDLVVIDLAQNG-YPIFENPYPMMIHESPVTCCEYLADCPVDLIPALYSVG--SRQKRQGYSKKEWPVSGG----NWGLG----TQSYPEIIITGHADGSVKFWDASAIMLQVLYKLKTAKVFEKARCK-----EEKPSTEIVDEDPFAIQLMSWCPESRMLCVAGVSAHVIIYRFSKQEITTEVVQLLELRLQHELNDLESPEGGGDQTPAPPTPSTSPSPQTAGPQTHTSSSSN-SSDGMRDNVPCLKVRSSPLKQSPGYQVELVVQLVWVSGEPPQQISSLAINSCYGLVVFGNSNGLAVVDYLQKTVLLNLGTVELYGSNDPYQRQPRSPR-------KSRQPSGG----------------------------LCDINEGSATSE-DRCKSPTSVLMS--------NHQHFYNGGGRG----------------------------------------------------------------AKMSRKLSLPTELKPDLVLLSVCPPRGS-------------------------------------------------------------------------------------------------------------------------------------------IPLDNRDNSFSRSRSSSVTSIDKETREAITSFYFCETYTRKADGG-LTPSLWVGTSLGTVLAISLNMPPAG---EQRLLQP-----------VIVSPCGTLFRLKGSVVRMAFLDSTGSILPSPFEPWYEPNAPANGEERDKVRKRRPVSVSPSTSQE-----------------------------------------------------------------------------------LNENQYAVVCSEKQAKVVILPSQTCVFKHN----------------------ITETSFVLRADVVQMNAGICVACFCANGHIMTLSLPGLRPLLDVNYLP----LTDM-----------------------------RIARTFCFTNLGQALYLTSPTEIQRITYSQEVCENLQEMLGELFTPVETPEAPNRGFFKGLFGGGAQSLDRMELFGETGAGKAPRSLAQHIPGPGGIEGMKGAASGIVGDLARARIALDERGQKLSEVEERTAAMMASADSFSKHAHEMMLKCKDKKWYQF------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32T9L0-1", "uniprot_id": "A0AB32T9L0_DANRE", "id": "A0AB32T9L0-1", "name": "Syntaxin-binding protein 5-like", "aln": "MHISAFVSHSLENNMKKFNIRKVLDGLTAASSSS-------------SSA---AAASPQSGNDMIQETLQSEHFQLCKTVRHGFPYQPSSMAFDPVQKILAIGTQSGALRL--------FGRAGVECYCQHE--SG----SAVIQLEFLVNVGALVSALADDSIHLWNLRQKL--PAVLHSLKFN---------------RERITFCHLPFQSKWLYVGTERGNIHIVNVESFTLSGYVIMWN------KAIELSSKTHPGPVVHISDNPMDEGKLLIGFECGIVVLWDLKSKKADYRYNYDEAIHSVAWHH--EGKQFVCSHSDGTLTTWNVRAPAK----PAQIITPHGKQPKDGKKPEPCKPILKVEYKTTRAG-DPFMILCGGLSYDTVGRRACLTVMHGK-STAVLEMDYPIVDFLTLCETPYPNDFQEPYAVVVLLEKDLVVIDLAQIG-YPIFENPYPLSIHESPVTCCEYFADCPAEAIPALYSVG--SRQKRQGFSKKEWPISAG----NWGQG----TLSFSEIIITGHADGSIKFWDASALMLQVLYKLKTAKVFDKPRSK-----EEKSSTDIVDEDPFAIQMLSWCPESRVLCVAGVSAHVIVYRFSKQEVTTEVVQLLEVRMQCELNEVESPEGGGDQASAVSTPGTAPSPQTSLPQSHPSTSSNNSCDGLRDNVPCLKVRSSPLKQFPGYHVELLIQLVWVSGEPPQQITSLAINSAYGLVAFGNGNGLAVVDYIQKTLLLNVTTAELYGSTDPHHRQPRSPR-------KTRQPSADTLHKKSCMSGLSNFYSESVKKLRSSYLSLCDGNDASAAPE-ERCKSPTSGSGSPCNSD-EDSKQKFIERVKTKSKRISKTVAND----------------------------------------------------FAKISRKINMLADQKDDRRLRRHCSLPGKKQSCVKEM---------------------------------------------------------------------------------------------------------------------KRQRHTVSFRETSFCERNARDNSFSRSRSSSVTSIDRESREVISSFYFCDSLSKKSETL-AVPSLWVGTSLGSMLAIALTVPSTP---EQRMQQP-----------VGVSFCGSVVRLKGAILRMAQLDASGTVLPHIYEPWYEPNAPE--EERERPRRRRPT--SPPSSQE-----------------------------------------------------------------------------------NQDCQYAVVCSEKQAKVVALPSQHCIFEHN----------------------ITEASFVLRADVVTMTAGVAIACFCANGHIMTLSLPSLRPLLDVNYLP----LTDM-----------------------------RIARTFCFSNQGQALYLTSPTEIQRITYSQETCENLQEMLGEMFTLVETPEAPNRGFFKGLFGGGAQSLDREDLFGEVAAGKASRSLAQHIPGPGGMEGMKGAASGVVGELARARIALDERGQKLGELEERTAAMMASADSFSKHAHDMMLKYKDKKWYQL------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5DQR4-1", "uniprot_id": "STB5L_MOUSE", "id": "Q5DQR4-1", "name": "Syntaxin-binding protein 5-like", "aln": "--------------MKKFNFRKVLDGLTASSPGS-GSSSGSNSGG-AGSGSVHPGGTAGLPREEIQESLTSDYFQICKTVRHGFPYQPTALAFDPVQKILAIGTRTGAIRI--------LGRPGVDCYCQHE--SG----AAVLQLQFLINEGALVSASSDDTLHLWNLRQKR--PAILHSLKFN---------------RERITYCHLPFQSKWLYVGTERGNTHIVNIESFILSGYVIMWN------KAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKSKRAELRVYYDEAIHSIDWHH--EGKQFMCSHSDGSLTLWNLKSPSR----PFQTTVPHGKSQREGRKSESCKPILKVEYKTCRNS-EPFIIFSGGLSYDKACRRPSLTIMHGK-AITVLEMDHPIVEFLTLCETPYPNEFQEPYAVAVLLEKDLIVVDLTQTN-FPIFENPYPMDIHESPVTCTAYFADCPPDLILVLYSIG--VKHKKQGYSNKEWPVSGG----AWNLG----AQTYPEIIITGHADGTIKFWDASAMTLQMLYKLKTSKVFEKQKAG-----EGKQTCELVEEDPFAVQMIYWCPESRIFCVSGVSAYVIIYKFSRHEVTTEIVS-LEVRLQCDVEDIITP-EPETSPPFPDLSSQLPPSRSLSGSTNTVSSEG----VTKDSIPCLSVKTRPVRMPPGYQADLVIQLVWVDGEPPQQITSLSISSAYGIVAFGNCTGLVVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPR-------KNRQFIADNF----CMRGLSNFYPDLTKRIRTSYQSLTELNDSPVPLELERCKSPTSDHVNGHCTSPTSQSCSSGKR--LSSADVSKVNRWG----------------------------------------------------PGRPPFRKAQSAACMEISLP---------------------------------------------------------------------------------------------------------------------------------------------------VTTEETRENSYNRSRSSSISSIDKDSKEAITALYFMESFARKNDST-VSPCLFVGTSLGMVVLISLNLPSSD---EQRFTEP-----------VVVLPSGTFLSLKGAVLTFSCMDRTGSLMQPPYEVWRDPNNTD---ENEKTWKRKLVMNYSSSSQE-----------------------------------------------------------------------------------MGDHQYTIICSEKQAKVFSLPSQTCLYVHN----------------------ITETSFILQADVVVMCNSACLACFCANGHIMIMSLPSLRPMLDVNYLP----LTDM-----------------------------RIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCDNIQDMLGDLFTPIETPEAQNRGFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRARIALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZU84-1", "uniprot_id": "D3ZU84_RAT", "id": "D3ZU84-1", "name": "Syntaxin-binding protein 5-like", "aln": "--------------MKKFNFRKVLDGLTASSPGS-GSSSGSNSGG-AGSGSVHPGGTAGVLREGIQESLISECFQICKTVRHGFPYQPTALAFDPVQKILAIGTRTGAIRI--------LGRPGVDCYCQHE--SG----AAVLQLQFLINEGALVSASSDDTLHLWNLRQKR--PAILHSLKFN---------------RERITYCHLPFQSKWLYVGTERGNTHIVNIESFILSGYVIMWN------KAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKSKRAELRVYYDEAIHSIDWHH--EGKQFMCSHSDGSLTLWNLKSPSR----PFQTTVPHGKSQREGRKSESCKPILKVEYKTCRNS-EPFIIFSGGLSYDKACRRPSLTIMHGK-AITVLEMDHPIVEFLTLCETPYPNEFQEPYAVAVLLEKDLIVVDLTQTN-FPIFENPYPMDIHESPVTCTAYFADCPPDLILVLYSIG--VKHKKQGYSNKEWPVSGG----AWNLG----AQTYPEIIITGHADGTIKFWDASAMTLQMLYKLKTSKVFEKQKVG-----DGKQTCEIVEEDPFAVQMIYWCPESRIFCVSGVSAYVIIYKFSRHEITAEIVS-LEVRLQCDVEDIITP-EPETSPPFPDLSSQLPSSRSLSGSTNTVSSEG----VTKDSIPCLSVKTRPVRMPPGYQADLVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCTGLVVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPR-------KNRQFIADNF----CMRGLSNFYPDLTKRIRTSYQSLTELNDSPVPLELERCKSPTSDHVNGHCTSPTSQSCSSGKR--LSSADVSKVNRWG----------------------------------------------------PGRPPFRKAQSAACMEISLP---------------------------------------------------------------------------------------------------------------------------------------------------VTTEETRENSYNRSRSSSISSIDKDSKEAITALYFMESFARKNDST-VSPCLFVGTSLGMVILISLNLPSSD---EQRFTEP-----------VVVLPSGTFLSLKGAVLTFSCMDRTGNLMQPPYEVWRDPNNTD---ENEKTWKRKLVMNYSSSSQE-----------------------------------------------------------------------------------MGDHQYTIICSEKQAKVFSLPSQTCLYVHN----------------------ITETSFILQADVVVMCNSACLACFCANGHIMIMSLPSLRPMLDVNYLP----LTDM-----------------------------RIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCDNIQDMLGDLFTPIETPEAQNRGFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRARIALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2K9-1", "uniprot_id": "STB5L_HUMAN", "id": "Q9Y2K9-1", "name": "Syntaxin-binding protein 5-like", "aln": "--------------MKKFNFRKVLDGLTASSPGS-GSSSGSNSGGGAGSGSVHPAGTAGVLREEIQETLTSEYFQICKTVRHGFPHQPTALAFDPVQKILAIGTRTGAIRI--------LGRPGVDCYCQHE--SG----AAVLQLQFLINEGALVSASSDDTLHLWNLRQKR--PAILHSLKFN---------------RERITYCHLPFQSKWLYVGTERGNTHIVNIESFILSGYVIMWN------KAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKSKRAELRVYYDEAIHSIDWHH--EGKQFMCSHSDGSLTLWNLKSPSR----PFQTTIPHGKSQREGRKSESCKPILKVEYKTCKNS-EPFIIFSGGLSYDKACRRPSLTIMHGK-AITVLEMDHPIVEFLTLCETPYPNEFQEPYAVVVLLEKDLIVVDLTQSN-FPIFENPYPMDIHESPVTCTAYFADCPPDLILVLYSIG--VKHKKQGYSNKEWPISGG----AWNLG----AQTYPEIIITGHADGSIKFWDASAITLQMLYKLKTSKVFEKQKVG-----EGKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVSAYVIIYKFSRHEITTEIVS-LEVRLQYDVEDIITP-EPETSPPFPDLSAQLPSSRSLSGSTNTVASEG----VTKDSIPCLNVKTRPVRMPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCNGLAVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPR-------KNKQFIADNF----CMRGLSNFYPDLTKRIRTSYQSLTELNDSPVPLELERCKSPTSDHVNGHCTSPTSQSCSSGKR--LSSADVSKVNRWG----------------------------------------------------PGRPPFRKAQSAACMEISLP---------------------------------------------------------------------------------------------------------------------------------------------------VTTEENRENSYNRSRSSSISSIDKDSKEAITALYFMDSFARKNDST-ISPCLFVGTSLGMVLIISLNLPLAD---EQRFTEP-----------VMVLPSGTFLSLKGAVLTFSCMDRMGGLMQPPYEVWRDPNNID---ENEKSWRRKVVMNSSSASQE-----------------------------------------------------------------------------------IGDHQYTIICSEKQAKVFSLPSQTCLYVHN----------------------ITETSFILQANVVVMCSSACLACFCANGHIMIMSLPSLRPMLDVNYLP----LTDM-----------------------------RIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCDNLQDMLGDLFTPIETPEAQNRGFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRARIALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SQE2-1", "uniprot_id": "STB5L_DANRE", "id": "Q5SQE2-1", "name": "Syntaxin-binding protein 5-like", "aln": "--------------MKKF--RKVLDGLTTSSPVNPGGSPG------CGSAAGTPSAAPTPRELEIQETLMSEHFQICKTVRHGFPYQPTALAFDPVQKILAIGSRSGGIRMYPFLSFPHLGRPGVDCHSQHE--SG----AAVLQMQFLINEGALVTACADDTLHLWSLRQRL--PAILHSLKFN---------------RERITFCHLPFQSKWLYVGTERGNTHIVNIESFILSGYVIMWN------KAIELSTKTHPGPVVHLSDSPKDEGKLLIGFESGTIVMWDLRAKRADFRIYYDEAIHSVSWHH--EGRQFMCSHSDGSLSMWNMRNTAK----PFQVTFPHGKTQRDGRK-ESCKPILKVEYKTSRNSSEAFVIFSGGLSYDKAGRRPTLTIMHGK-AITVLEMDYPIVDFMVLCETPYLNEVQEPYAVVVLLEKDFVVVDLTQSN-FPIFENPYPMDVHESPVTCTAYFADCPPDIIPVLYSIG--AKHKKTGYSHKEWPVSGG----TWTVG----SQTYPEIIITGHADGSIKFWDATAITLQMLYKLKTSKVFEKPKTG-----DMGRSADLVEEDPYAVQMISWCPQSRIFCVVGISAHVILYRFSKHDANTIITS-LELRLQCEMEDVISPSDTENTPCFSDPSGHSPQPQPPSPRSNTPDS-------VRDSIPCLKVKDRMIRMPPGYQAELVVQLLWVDGEPPQQITCLDLNSAYGLLALGNCNGLAVVDYLQKTILLCMSTLELYGSADPFQRLTRSPR-------KNRQSTSG----------------------------LTELSDNQVSLDLERSKSPTSDHVNGHCTSPTSQPCPSGRARVPGGPEGPRLARRG----------------------------------------------------PGRPPFRKAQSAACMEVSLP---------------------------------------------------------------------------------------------------------------------------------------------------VSS-LTEENSFSRSRSSSVSSIDRETKEAVTTLQFAESYGRKSDSL-PTPCLWVGTSLGLVLIIPMSIPTDE---QERQEDP-----------VTVAPTGTVLMLKGSVLRFGFLDCGGALINSPYEVWRDQHAPD---DPDRPRKRKLVNFSPSSSQEA----------------------------------------------------------------------------------CGDGHLAVVCSERQAKVFYMPSQACLYVHN----------------------ITESSFVLRADVVSVSNSVCLACFCANGHIMILSLPSLRPLLDVSYLP----LTDM-----------------------------RIARTFCFTNGGQALYLCSPTEIQRITYSQEMCE----TLGELFTPIETPEAQNRGFLKGFFGGNAQTFDREELFGEASAGKASRSLAQHIPGQGGIEGMKAAAGGVVGDLARARIALDERGQRLGELEERTALMMTSAETFSKHAHELMLKCKDKKWYQF------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYK6-1", "uniprot_id": "Q9VYK6_DROME", "id": "Q9VYK6-1", "name": "", "aln": "--------------MKKFTFKGVLDGFRQSVQPQ-----------------------ATRQEQEIQEQLKADHFTLKKTFRHGFPYSPTSFAFDPVQKLLAIGDKSGYIRI--------LGRPGVDAHAKHEGESE----CAVLFAQFLVNEGALVTVTADDTIHLWSIRQKT--PRIVQSLKFQ---------------RERVTCIHLPVGSKWLYVGTEKGNIHVVHIDTFALSGYIINWN------KAIEVVRTSHPGAVIALCDNPLDANKLLIAFECGLLVLWDLKAKCAELRWQAAEAVKSLAWHY--EGKYFVSSHTDGSICSWPTKPQAK----PQSQVCPHAKINKDGNA-EKCKPIYKVDLKSSATG-ETFTIFSGGMPSEKGSKSNCITVMVGK-ATTVLEMEHAVCDFITLCENPWPCETQEPYAIAVLLQYDLVLIDLLTPG-FPCFESPYPMDLHESPVTCCTYLTDCPSDLVPAFYSVGRTTTSKKSCFSEREWPISGG----EWSPA----SCSYSEIVITGHQDGSLKFWDSGAGTLQILYKLKTAKMFEKPRS-------HVAHSHPESDNPLAVHLIFLCSESRRLCVAGAMGQVMLFKFRKVESTSEVLV-LEIPILYENFDDIYG----TSPECDFLTGHQVQKAESSDSDKTAECS-------------LKVRNGAQRKPPGFQSQLVCLTTGPNRRN-VQVTSLCISSSYGLMAYGTEYGLVIIDIIQKICLLSVACPDLYGAHDPYSRTPKSPKRIENKEEQSRSPSSDQLN--------DTTSPDSPSLEFVPEAGETSAHDGVATATSSRPSSPDPVVNSARETLLSGSAAATAAAAASAAVMMAKSPQRDDAAPKELQDRRKSMSWKTFNLKRQLSKVNMKIGGLNVNTDMESLKNSSIFYTPKEVSPEAATPPATEEEATPEGKEDESLDDGEMATNAGAAAAASPSPAVRGKFRSSTTDSPDEGASSSIASGIRRVDFEQPAGVEVERPNNLPLADAPAPLKPARQKFKEKSRDQRLLSVPNIKYQPRDSRGGARNLKNDVSPLMGGGGGGGGVVGASSGIGGSVAGGKKIHKLDGTFSRSRSSSMSSIDMSSSESVTCLAFIESYAKRNDILTLVPTLWIGTSFGSILTLFITMPERD---VRKSQPV-----------LITINGGPVVRLKGSITSMSFLDSYGSIIPYTFETWRDEKRDNKDRTPTKSSSRTSPTFTPTTANTLSNTSVAGGASAGGGAGGGGGAGGGAASGGAAAGGPAGGGAGAGSAAGAAGGVGSGVTSGGGMSSSSASSSGISGSVSTGLETLTDRQYIVIASEKQTKVFDVANQCCINRIQ----------------------LSEMDFAVKAETITMKDGSCLATYLSNGHLMVHSLPSLKLLLDTDFLP----LMELSFQTKCKQGIVDPMLSIWGQQIIVHEDTTQISKIFCFSHKGHGLYMASPTEIQKFTISSEFCQFILEMMGELYTVHEMPEQPKEGFFKGLFGGGAKLLDREELFGEQS-GKPNRSVARHIPGP-NLEQLGQRASTAASEISRAHQLAMERGEKLNLLEERAERMANTAQDFSGTAHQLMLKYKDKKWYQL------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12038-1", "uniprot_id": "SRO7_YEAST", "id": "Q12038-1", "name": "Exocytosis protein SRO7", "aln": "----MFGSKRLKNVKEAFKSLKGQNSETPIENSK----ASFKSKNSKTSTISKDAKSSSSLKIPISSNNKNKIFSLAETNKYGMSSKPIAAAFDFTQNLLAIATVTGEVHI--------YGQQQVEVVIKLEDRS------AIKEMRFVKG-IYLVVINAKDTVYVLSLYSQKVLTTVFVP--------------------GKITSIDTDASLDWMLIGLQNGSMIVYDIDRDQLSSFKLDNLQ------KSSFFPAARLSPIVSIQWNPRDIGTVLISYEY-VTLTYSLVENEIKQSFIYELPPFAPGGDFS-----EKTNEKRTPKVIQSLYHPNS-----LHIITIHEDN--------------SLVFWDANSG----HMIMARTVFETEINVPQPDYIRDS---STNAAKISKVYWMCENNPEYTSLLISHKSISRGDNQSLTMIDLGYTPRYSITSYEGMKNYYANPKQMKIFPLPTNVPIVNILPIPRQSPYFAGCHNPGLILLILGN-------------GEIETMLYPSGIFTDKASLFPQNLSWLRPLATTSMAASVPNKLWLG-ALSAAQNKDYLLKGGVRTKRQKLPAEYGTAFITGHSNGSVRIYDASHGDIQDNASFEVNLSRTLNKAKELAVDKISFAAETLELAVSIETGDVVLFK---------------------------------YEVNQFYSVE-------NRPESGDLEMNFRRFSLNNTNGVLVDVRDRAPTGVRQGFMPSTAVHANKGKTSAINN------------------------------------------------SNIGFVGIAYAAGSLMLIDRRGPAIIYMENIREISGAQSACVTCIEFVIMEYG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DDGYSSILMVCGTDMGEVITYKILPASGGKFDVQLMDITNVTSKGPIHKIDAFSKETKSSC---------------------LATIPKMQNLSKGLCIPGIVLITGFDDIRLITLGKSKSTHKGFKYPLAATGLSYISTVEKNNDRKNLT-------------------------------------------------------------------------------------VIITLEINGHLRVFTIPDFKEQMSEH------------------------------------IPFPIAAKYITESSVLRNGDIAIRVSEFQASLFSTVKEQD--------------------------------TLAPVSDTLYINGIRIPYRPQVNSLQWARGTVYCTPAQLNELLGGVNRPASKYKESI------------------IAEGSFSERSSDDNNANHPEHQYTKPTRKGRNSSYGVLRNVSRAVETRWDAVEDRFNDYATAMGETMNEAVEQTGKDVMKGALGF------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : :* .:*:. .* : .:. .::*:. :* ::: * *: : . : . :: . : : : ::: . :* : * : : : . :::.:. : :. . : : . :: . : : : .: ** : .. . : .. : :* .. :: * : . . . . : . : . : : : . . . : : . .. *. : . . . . : : : . : . : : : . : : . . . . : .:. . . : ..: : .: : : : : : ", "identical_positions": 14, "similar_positions": 137, "identity": "0.82%" }, { "cls_id": "homologset.agr.SGD:S000006237", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M9C9-1", "uniprot_id": "F1M9C9_RAT", "id": "F1M9C9-1", "name": "histidine--tRNA ligase", "aln": "MPHLGPLRCRTWAALLGQLLRPPRTVCNRAV------------------------------------------GCHSQVAKAVLTSEQLKPHQQ--KPNFIIKVPKGTRDLSPQQMVVREKILDKIISCFKRHGAKGLDTPAFELKEMLTEKYEDNFGLMYDLEDQGGELLSLRYDLTVPFARYLAMNKLKRMKRYQVGKVWRRESPAIVQGRYREFCQCDFDIAGEFDPMIPDAECLRIMCEILSGLQLGDFLIKVNDRRVVDGMFAVCGVPESKFRTICSSMDKLDKMSWEDVRLEMVAGKGLAPEVADRIGDYVQCHGGISLVEELFK-DPRLSQSQLALQGLGDLKLLFEYLRLFGIADKISLDLSLARGLDYYTGVIYEAVLLESP----------AQAGKETLN----VGSVAAGGRYDRLVAQFDP----KGHSVPCVGLSIGVERIFYLVEQKMKISCEKVRTTETQVFVATPQ-----KNFLQERLKIIAQLWDAGIKAEMLYKNNPKLLTQLHYCEKEDIPLMVIIGEQEQNEGVVKLR----SVASREEVTVNRESLVAEIQKRLSES---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99KK9-1", "uniprot_id": "SYHM_MOUSE", "id": "Q99KK9-1", "name": "Histidine--tRNA ligase, mitochondrial", "aln": "MPHLGPLRRRAWAALLGQLLRPPSTVCTR--------------------------------------------GCHSQVAKAVLTSEQLKSHQE--KPNFVIKVPKGTRDLSPQQMVVREKILDKIISCFKRHGAKGLDTPAFELKEMLTEKYEDNFGLMYDLKDQGGELLSLRYDLTVPFARYLAMNKLKKMKRYQVGKVWRRESPAIAQGRYREFCQCDFDIAGEFDPMIPDAECLRIMCEILSGLQLGDFLIKVNDRRVVDGIFAVCGVPESKLRTICSSMDKLDKMSWEGVRHEMVAKKGLAPEVADRIGDFVQYHGGISLVEDLFK-DPRLSQSQLALQGLGDLKLLFEYLRLFGIADKISLDLSLARGLDYYTGVIYEAVLLESP----------AQAGKETLS----VGSVAAGGRYDNLVAQFDP----KGHHVPCVGLSIGVERIFYLVEQKMKMSGEKVRTTETQVFVATPQ-----KNFLQERLKIIAELWDAGIKAEMLYKNNPKLLTQLHYCEKADIPLMVIIGEQERNEGVIKLR----SVASREEVTINRESLVAEIQKRLSES---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49590-1", "uniprot_id": "SYHM_HUMAN", "id": "P49590-1", "name": "Histidine--tRNA ligase, mitochondrial", "aln": "MPLLGLLPRRAWASLLSQLLRPPCASCTGAV------------------------------------------RCQSQVAEAVLTS-QLKAHQE--KPNFIIKTPKGTRDLSPQHMVVREKILDLVISCFKRHGAKGMDTPAFELKETLTEKYGEDSGLMYDLKDQGGELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRESPTIVQGRYREFCQCDFDIAGQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDGMFAVCGVPESKFRAICSSIDKLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQ-DPRLSQNKQALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAVLLQTP----------TQAGEEPLN----VGSVAAGGRYDGLVGMFDP----KGHKVPCVGLSIGVERIFYIVEQRMKTKGEKVRTTETQVFVATPQ-----KNFLQERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTGIPLVVIIGEQELKEGVIKIR----SVASREEVAIKRENFVAEIQKRLSES---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61035-1", "uniprot_id": "HARS1_MOUSE", "id": "Q61035-1", "name": "Histidine--tRNA ligase, cytoplasmic", "aln": "MADRAAL--EELVRLQGAHVRGLKEQKASAE------------------------------------------QIEEEVTKLLKLKAQLGQDEG--KQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLTGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGQFDPMIPDAECLKIMCEILSSLQIGNFLVKVNDRRILDGMFAVCGVPDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQ-DPKLSQNKQAVEGLGDLKLLFEYLILFGIDDKISFDLSLARGLDYYTGVIYEAVLLQMP----------TQAGEEPLG----VGSIAAGGRYDGLVGMFDP----KGRKVPCVGLSIGVERIFSIVEQRLEASEEKVRTTETQVLVASAQ-----KKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLR----SVASREEVDVRREDLVEEIRRRTNQPLSTC-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8J8YFS5-1", "uniprot_id": "A0A8J8YFS5_RAT", "id": "A0A8J8YFS5-1", "name": "Histidine--tRNA ligase, cytoplasmic", "aln": "MADRAAL--EELVRLQGAHVRGLKEQKASAE------------------------------------------QIEEEVTKLLKLKAQLGHDEG--KQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLTGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGQFDPMIPDAECLKIMCEILSSLQIGNFQVKVNDRRILDGMFAVCGVPDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQ-DPKLSQNKQAVEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQMP----------TQAGEEPLG----VGSIAAGGRYDGLVGMFDP----KGRKVPCVGLSIGVERIFSIVEQKLEASEEKVRTTETQVLVASAQ-----KKLLEERLKLISELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLR----SVTSREEVDVRREDLVEEIRRRTSQPLSM------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12081-1", "uniprot_id": "HARS1_HUMAN", "id": "P12081-1", "name": "Histidine--tRNA ligase, cytoplasmic", "aln": "MAERAAL--EELVKLQGERVRGLKQQKASAE------------------------------------------LIEEEVAKLLKLKAQLGPDES--KQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQ-DPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTP----------AQAGEEPLG----VGSVAAGGRYDGLVGMFDP----KGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQ-----KKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLR----SVTSREEVDVRREDLVEEIKRRTGQPLCIC-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QI36-1", "uniprot_id": "HARS1_DANRE", "id": "E9QI36-1", "name": "Histidine--tRNA ligase", "aln": "MADKAQL--QEAIKTQGEVVRKLKSEKASKE------------------------------------------QIDEEVARLLQLKAQLGGDEG--KHVFVLKTAKGTRDYNPKQMAIREKVFNIIINCFKRHGAETIDSPVFELKETLTGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKITNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGQYDAMIPDAECLKLVYEILSELDLGDFRIKVNDRRILDGMFAICGVPDEKFRTICSTVDKLDKLAWEEVKKEMVNEKGLSEEVADRIRDYVSMQGGKDLAERLLQ-DPKLSQSKQACAGITDMKLLFSYLELFQITDKVVFDLSLARGLDYYTGVIYEAILTQANPAP-AS-TPAEQNGAEDAGV--SVGSVAGGGRYDGLVGMFDP----KGRKVPCVGVSIGIERVFSIMEQKAELSSEKVRTTETQVLVASAQ-----KNLLEERLKLTAELWNAGIKAEVLYKKNPKLLSQLQHCEDTGIPLVAILGEQELKDGVVKLR----NVASREEVDVPRAELVDEVKKRTS-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQX8-1", "uniprot_id": "Q8IQX8_DROME", "id": "Q8IQX8-1", "name": "histidine--tRNA ligase", "aln": "MSDTREQ-ILEQIKVQGDLVRQLKAAKESKEKTAPSGGGRVSSSGVPAQRQQQQQPQKQQQAQVQQQQHEQLHQIDEEVARLLALKATLGGDAAPTNQKFTLKTPKGTRDYGPQQMTLRQGVLDKIVQVFKRHGGEAIDTPVFELKEVLTGKYGEDSKLIYDLKDQGGEILSMRYDLTVPLARYLAMNKISSIKRYHIAKVYRRDNPAMTKGRYREFYQCDFDIAGTYDPMLPDAECVKIVSEILDTLDIGDYVIKLNHRQLLDGMFQACGVPADSFRTICSAVDKLDKSPWADVRKEMVDEKGLDEAAADRIGEYVRLSGGAELVEQLLA-NEKLKAVPNAVKGLEGMKQLLKYCSIFGLDKRVSFDLSLARGLDYYTGVIYEGVLKGESATV-ASPAKTSQQNGEQANEPATVGSVAGGGRYDNLVGMFDP----RGKAVPCVGVSIGVERIFSVLEARAAASGLKLRTSDVEVYVASAH-----KGLHEQRLKVLNLLWDAGVKAEHSYKLNPKLLVQLQHCEEHQIPLVVVLGDAELAQGLVKLR----EVTTREETNVKLEDLAAEIRRRQQASA--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07263-1", "uniprot_id": "SYH_YEAST", "id": "P07263-1", "name": "Histidine--tRNA ligase, mitochondrial", "aln": "MLSRSLN--KVVTSIKSSSIIRMSSATAAAT-------------------------------------------SAPTANAANALKASKAPKKG--KLQVSLKTPKGTKDWADSDMVIREAIFSTLSGLFKKHGGVTIDTPVFELREILAGKYGEDSKLIYNLEDQGGELCSLRYDLTVPFARYVAMNNIQSIKRYHIAKVYRRDQPAMTKGRMREFYQCDFDVAGTFESMVPDSECLSILVEGLTSLGIKDFKIKLNHRKILDGIFQIAGVKDEDVRKISSAVDKLDKSPWEAVKKEMTEEKGQSEETADKIGEYVKLNGSLKEIHAVLSADANITSNEKAKQGLDDIATLMKYTEAFDIDSFISFDLSLARGLDYYTGLIYEVVTSASAPPENASELKKKAKSAEDASEFVGVGSIAAGGRYDNLVNMFSEASGKKSTQIPCVGISFGVERIFSLIKQRINSS-TTIKPTATQVFVMAFGGGKDWTGYLPERMKVTKQLWDAGIEAEYVYKAKANPRKQFDAAEKAGCHIAVILGKEEYLEGKLRVKRLGQEFADDDGELVSAADIVPIVQEKLSQIHEDGLNEVTRLIKGL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : . . . : . :*..***:* .*.:*: ::. : **:**. :*:*.***:* * ** :: *:*:*:*****: *:*******:***:***:: :***::.**:**:.*::.:** *** *****:** ::.*:**:**: :: * * * : :: :*:*.*:::**:* .** ...* *.*::***** .* *: **. ** .**:* ::* *. . . :: : .:. * *: .: *:.* * : . : :*************:*** : . * . ***:*.***** ** *. :. :****:*:*:**:* ::: : .::.: .:* * : . :*:*: **::*::** ** :.: *:. .*. : .::*. * :* :::: ..: : : .:. ::.: ", "identical_positions": 157, "similar_positions": 161, "identity": "26.43%" }, { "cls_id": "homologset.agr.SGD:S000006238", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MR0-1", "uniprot_id": "ACL6B_MOUSE", "id": "Q99MR0-1", "name": "Actin-like protein 6B", "aln": "MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEGGG--LELEGEKEKKG-KIFHIDTNALHVPRDGAEVMSPLKN-GMIEDWECFRAILDHTYSKHVKSEPNLHPVLMSEAPWNTR---AKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFISMQCRE----------------------------------LFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKLPQVSKSWHNYMCNEVIQDFQASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLRIPEGL--------------------FDPSNVKGLSG---NTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDRLNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQ-MWISKQEYEEGGKQCVERKCP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P86173-1", "uniprot_id": "ACL6B_RAT", "id": "P86173-1", "name": "Actin-like protein 6B", "aln": "MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEGGG--LELEGEKEKKG-KIFHIDTNALHVPRDGAEVMSPLKN-GMIEDWECFRAILDHTYSKHVKSEPNLHPVLMSEAPWNTR---AKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFISMQCRE----------------------------------LFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKLPQVSKSWHNYMCNEVIQDFQASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLRIPEGL--------------------FDPSNVKGLSG---NTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDRLNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQ-MWISKQEYEEGGKQCVERKCP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O94805-1", "uniprot_id": "ACL6B_HUMAN", "id": "O94805-1", "name": "Actin-like protein 6B", "aln": "MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEGGG--LELEGDKEKKG-KIFHIDTNALHVPRDGAEVMSPLKN-GMIEDWECFRAILDHTYSKHVKSEPNLHPVLMSEAPWNTR---AKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFISMQCRE----------------------------------LFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKLPQVSKSWHNYMCNEVIQDFQASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLRIPEGL--------------------FDPSNVKGLSG---NTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDRLNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQ-MWISKQEYEEGGKQCVERKCP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z2N8-1", "uniprot_id": "ACL6A_MOUSE", "id": "Q9Z2N8-1", "name": "Actin-like protein 6A", "aln": "MSGGVYGGDEVGALVFDIGSYTVRAGYAGEDCPKVDFPTAIGVVLERDDGSTMMEIDGDKGKQGGPTYYIDTNALRVPRENMEAISPLKN-GMVEDWDSFQAILDHTYKMHVKSEASLHPVLMSEAPWNTR---AKREKLTELMFEHYSIPAFFLCKTAVLTAFANGRSTGLILDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFITMQCRE----------------------------------LFQEMNIELIPPYMIASKEAVREGSPANWKRKEKLPQVTRSWHNYMCNCVIQDFQASVLQVSDSTYDEQVAAQMPTVHYEFPNGYNCDFGAERLKIPEGL--------------------FDPSNVKGLSG---NTMLGVSHVVTTSVGMCDIDIRPGLYGSVIVAGGNTLIQSFTDRLNRELSQKTPPSMRLKLIANNTTVERRFSSWIGGSILASLGTFQQ-MWISKQEYEEGGKQCVERKCP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O96019-1", "uniprot_id": "ACL6A_HUMAN", "id": "O96019-1", "name": "Actin-like protein 6A", "aln": "MSGGVYGGDEVGALVFDIGSYTVRAGYAGEDCPKVDFPTAIGMVVERDDGSTLMEIDGDKGKQGGPTYYIDTNALRVPRENMEAISPLKN-GMVEDWDSFQAILDHTYKMHVKSEASLHPVLMSEAPWNTR---AKREKLTELMFEHYNIPAFFLCKTAVLTAFANGRSTGLILDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFITMQCRE----------------------------------LFQEMNIELVPPYMIASKEAVREGSPANWKRKEKLPQVTRSWHNYMCNCVIQDFQASVLQVSDSTYDEQVAAQMPTVHYEFPNGYNCDFGAERLKIPEGL--------------------FDPSNVKGLSG---NTMLGVSHVVTTSVGMCDIDIRPGLYGSVIVAGGNTLIQSFTDRLNRELSQKTPPSMRLKLIANNTTVERRFSSWIGGSILASLGTFQQ-MWISKQEYEEGGKQCVERKCP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12406-1", "uniprot_id": "ARP7_YEAST", "id": "Q12406-1", "name": "Actin-related protein 7", "aln": "------MTLNRKCVVIHNGSHRTVAGFSNVELPQCIIPSSY--IKRTDEGGEAEFIFG---------TYNMIDAAAEKRNGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAILERYYELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFGGDFLDFQVHERLAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSEKDLFELERYYKEQADIYAKQQEQLKQMDQQLQYTALTGSPNNPLVQKKNFLFKPLNKTLTLDLKECYQFAEYLFKPQLISDKFSPEDGLGPLMAKSVKKAGASINSMKANTSTNPNGLGTSHINTNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFP-QYKLTTFANQVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLKRDRKQSQATNATN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:*:. **. . **::. : *: :*:: : : *. : * : :* *:. *. : :.. *: :*:.:. : *. ::* ... *:::: .. * : * *: ** *:: .:*.* : .: *:: *:*:.:::* **: .. *: ** *:::.:*:* :.***: :* :* *:. ::: :: :. :* : *::*:* *: :. : . :: .. :. .. :: :: :: : :: : :::: :** .:* :**. ** :* .: .::* .:. :: . * .**::*..:*::.: :*: :*** : * . :*. :*.: ::*::. *:*. :*.* ::. * **::** :: : :.. ", "identical_positions": 79, "similar_positions": 178, "identity": "15.96%" }, { "cls_id": "homologset.agr.SGD:S000006239", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P20477-1", "uniprot_id": "GLNA1_DROME", "id": "P20477-1", "name": "Glutamine synthetase 1, mitochondrial", "aln": "MALRVAGLFLKKELVAPATQQLRLLRTGNTTRSQFLANS----PNTALDKSILQRYRNLETPANRVQATYLWIDGTGENIRLKDRVLDKVPSSVEDLPDWQYDGSSTYQAHGENSDTTLKPRAIYRDPFKPGKNDVIVLCDTYSADGKPTASNKRAAFQAAIDLISDQEPWFGIEQEYTLLDVDGRPFGWPENGFPAPQGPYYCGVGADRVYARDLVEAHVVACLYAGIDFAGTNAEVMPAQWEFQIGP-AGIKACDDLWVSRYILQRIAEEYGVVVTFDPKPMEGQWNGAGAHTNFSTKEMRADGGIKAIEEAIEKLSKRHERHIKAYDPKEGKDNERRLVGRLETSSIDKFSWGVANRAVSVRVPRGVATAGKGYLEDRRPSSNCDPYAVCNAIVRTCL--LNE------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20478-1", "uniprot_id": "GLNA2_DROME", "id": "P20478-1", "name": "Glutamine synthetase 2, cytoplasmic", "aln": "------------------------------MSARILEDS----PNARINKTILDRYLSLPLQENIVQATYVWIDGTGEDLRCKDRTLDFIPQSPKELPVWNYDGSSCYQAEGSNSDTYLYPVAIYKDPFRRG-NNILVMCDTYKFDGTPTDTNKRKTCLEVANKCAAEEPWFGIEQEYTFLDFDGHPLGWPKNGFPGPQGPYYCGVGANKVYARDIVDAHYRACLYAGIKVSGTNAEVMPAQWEFQVGPCEGISIGDDLWMARFLLHRISEEFGIVSTLDPKPMPGDWNGAGAHTNVSTKAMREDGGIRDIEKAVAKLSKCHERHIRAYDPKQGQDNARRLTGKHETSSINDFSAGVANRGCSIRIPRGVNDDGKGYFEDRRPSSNCDPYSVVEAILRTIC--LDE------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P09606-1", "uniprot_id": "GLNA_RAT", "id": "P09606-1", "name": "Glutamine synthetase", "aln": "-----------------------------------MATS----ASSHLNKGIKQMYMNLPQGE-KIQLMYIWVDGTGEGLRCKTRTLDCDPKCVEELPEWNFDGSSTFQSEGSNSDMYLHPVAMFRDPFRRD-PNKLVFCEVFKYNRKPAETNLRHSCKRIMDMVSSQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGIKITGTNAEVMPAQWEFQIGPCEGIRMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLRCIEEAIDKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSASIRIPRIVGQEKKGYFEDRRPSANCDPYAVTEAIVRTCL--LNETGDEPFQYKN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15105-1", "uniprot_id": "GLNA_MOUSE", "id": "P15105-1", "name": "Glutamine synthetase", "aln": "-----------------------------------MATS----ASSHLNKGIKQMYMSLPQGE-KVQAMYIWVDGTGEGLRCKTRTLDCEPKCVEELPEWNFDGSSTFQSEGSNSDMYLHPVAMFRDPFRKD-PNKLVLCEVFKYNRKPAETNLRHICKRIMDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGVKITGTNAEVMPAQWEFQIGPCEGIRMGDHLWIARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLKCIEEAIDKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRGASIRIPRTVGQEKKGYFEDRRPSANCDPYAVTEAIVRTCL--LNETGDEPFQYKN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15104-1", "uniprot_id": "GLNA_HUMAN", "id": "P15104-1", "name": "Glutamine synthetase", "aln": "-----------------------------------MTTS----ASSHLNKGIKQVYMSLPQGE-KVQAMYIWIDGTGEGLRCKTRTLDSEPKCVEELPEWNFDGSSTLQSEGSNSDMYLVPAAMFRDPFRKD-PNKLVLCEVFKYNRRPAETNLRHTCKRIMDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADRAYGRDIVEAHYRACLYAGVKIAGTNAEVMPAQWEFQIGPCEGISMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSASIRIPRTVGQEKKGYFEDRRPSANCDPFSVTEALIRTCL--LNETGDEPFQYKN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B814-1", "uniprot_id": "A0A8M2B814_DANRE", "id": "A0A8M2B814-1", "name": "Glutamine synthetase", "aln": "------------------MFILDGLRAG--SFGLHMEWSQFYITDSSLNKALRQQYLSLPQGP-FCQVTYIWIDGSGEGLRNKTRTMESEPKSVADLPEWTFDGSSTGQSEGHNSDMLLIPVRMFRDPFLLD-PNKLVLCEVLKHTREPAESNHRNKCNKVMEKVKGLQPWFGMEQEYTLLGVDGHPYGWPRLGFPKPQGLYYCSVGADRAFGRDIVDCHYKACLYAGIKITGTNAEVMPSQWEYQVGPCEGIEVADHLWMSRFVLHRVCEDFGVVATLDPKPMVGDWNGAGCHINVSTASMREEEGIEHIEKAIEKLSRRHEEHIRVYDPHGGEDNKRRLTGRHETSSIHDFSAGVANRGASIRIPRQVGQEKCGYFEDRRPAANCDPYAVTCEMAVTCM--LDDVHE---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32288-1", "uniprot_id": "GLNA_YEAST", "id": "P32288-1", "name": "Glutamine synthetase", "aln": "-----------------------------------MAEA------SIEKTQILQKYLELDQRG-RIIAEYVWIDGTG-NLRSKGRTLKKRITSIDQLPEWNFDGSSTNQAPGHDSDIYLKPVAYYPDPFRRG-DNIVVLAACYNNDGTPNKFNHRHEAAKLFAAHKDEEIWFGLEQEYTLFDMYDDVYGWPKGGYPAPQGPYYCGVGAGKVYARDMIEAHYRACLYAGLEISGINAEVMPSQWEFQVGPCTGIDMGDQLWMARYFLHRVAEEFGIKISFHPKPLKGDWNGAGCHTNVSTKEMRQPGGMKYIEQAIEKLSKRHAEHIKLY----GSDNDMRLTGRHETASMTAFSSGVANRGSSIRIPRSVAKEGYGYFEDRRPASNIDPYLVTGIMCETVCGAIDNADMTKEFERESS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : .. : : * .* *:*:**:* .:* * *.:. . :** * :**** *: * :** * * : *** . : :*:. . * * * . ***:*****::. . *** *:* *** ***.***.:.:.**:::.* ******:..:* ******:***:*:** ** *.**::*:.*:*:.*::*: ::.***: *:*****.* *.** ** *:. **:*: ***: * **: * * ** **.* **:.: ** *****. *:*:** * **:*****::* **: * : * ::: ", "identical_positions": 142, "similar_positions": 91, "identity": "33.97%" }, { "cls_id": "homologset.agr.SGD:S000006240", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UI12-1", "uniprot_id": "VATH_HUMAN", "id": "Q9UI12-1", "name": "V-type proton ATPase subunit H", "aln": "-MTKMDIRG-AVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISAEDCEFIQRFEMKRSPEEKQEMLQTEG---------SQCAKTFINLMTHICKEQTVQYILTMVDDMLQENHQRVSIFFDYARCSKNTAWPYFLPMLNRQDPFTVHMAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQKLRGSGVAVETGTVSSSDSSQYVQCVAG-CLQLMLRVNEYRFAWVEADGVNCIMGVLSNKCGFQLQYQMIFSIWLLAFSPQMCEHLRR--YNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALAMIQCKVLKQLENLEQQKYDDEDISEDIKFLLEKLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTKLLEVSD---------DPQVLAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNWEYLGKQLQSEQPQTAAARS---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BVE3-1", "uniprot_id": "VATH_MOUSE", "id": "Q8BVE3-1", "name": "V-type proton ATPase subunit H", "aln": "-MTKMDIRG-AVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISAEDCEFIQRFEMKRSSEDKQEMLQTEG---------SQCAKTFINLMTHISKEQTVQYILTMVDDMLQENHQRVSIFFDYAKRSKSTAWPYFLPMLNRQDPFTVHMAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQKLRGSGVAVETGTISSSDSSQYVQCVAG-CLQLMLRVNEYRFAWVEADGVNCIMGVLSNKCGFQLQYQMIFSIWLLAFSPQMCEHLRR--YNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALAMIQCKVLKQLENLEQQKYDDEDISEDIKFLLEKLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTKLLEVSD---------DPQVLAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNWEYLGKQLQSEQPQTAAARS---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZWI2-1", "uniprot_id": "A0A8I5ZWI2_RAT", "id": "A0A8I5ZWI2-1", "name": "V-type proton ATPase subunit H", "aln": "-MTKMDIRG-AVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISAEDCEFIQRFEMKRCSEEKQEMLQTEG---------SQCAKTFINLMTHISKEQTVQYILTMVDDMLQENHQRVSIFFDYAKRSKSTAWPYFLPMLNRQDPFTVHMAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQKLRGSGVAVETGTISASDSSQYVQCVAG-CLQLMLRVNEYRFAWVEADGVNCIMGVLSNKCGFQLQYQMIFSIWLLAFSPQMCEHLRR--YNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALAMIQCKVLKQLENLEQQKYDDEDISEDIKFLLEKLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTKLLEVSD---------DPQVLAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNW-YVSIQASQNRPNTSYAEVTVVRSQLCS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B0R0V8-1", "uniprot_id": "B0R0V8_DANRE", "id": "B0R0V8-1", "name": "V-type proton ATPase subunit H", "aln": "----MDIRG-AVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISGEDCEFIKKFEVAG-SEDKQAILTNEG---------HQCAKTFLNLMAHISKEQTVQYILTLIDDTLQENHQRVNIFFDYAKKTKNTAWSYFLPMLNRQDLFTVHMAARIIAKLAAWGRDLMEGSDLNYYFNWIKTQLSSQKLHGTGAEPGTGTISPSESSQYVQCVAG-CLQLMLRVNEYRFAWVEADGVNCITAVLSNKCGFQLQYQMIFCVWLLAFSPQLCEQLRR--YNVVPALSDILQESVKEKVTRIILAAFRNLLEKSAERETRQEYALAMIQCKVLKQLENLDQQKYDDEDITDDIKFLLERLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTRLLEVSD---------DPQVIAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQLVRYNALLAVQKLMVHNWEYLGKQLQSTEQTTPAVAARS-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3J1-1", "uniprot_id": "VATH_DROME", "id": "Q9V3J1-1", "name": "V-type proton ATPase subunit H", "aln": "MTTALYLPEENIDMIAATSVLQQQAADIRTRTINWASYMQSQMISEEDYKAISALDKSR-----ASFLAQNS---------SQVVKTLLNLVSHLSKDSTIQYILVLLDDLLQEDRSRVDLFHDTAGKLKQCIWGPFLNLLNRQDGFIVNMSSRILAKFACWGHETMPKSDLNFYLQFLKDQLAS------------------NNNEYIQSVAR-CLQMMLRVDEYRFAFVGVDGISTLIRILSTRVNFQVQYQLIFCLWVLTFNPLLAAKMNK--FSVIPILADILSDCAKEKVTRIILAVFRNLIEKPEDSSVAKDHCIAMVQCKVLKQLSILEQRRFDDEDITADVEYLSEKLQNSVQDLSSFDEYATEVRSGRLEWSPVHKSAKFWRENAQRLNEKNYELLRILVHLLETSK---------DAIILSVACFDIGEYVRHYPRGKHVLEQLGGKQIVMQHLGHEDPNVRYEALLAVQKLMVHNWEYLGKQLEKENENQKQGAAPIAGKA---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41807-1", "uniprot_id": "VATH_YEAST", "id": "P41807-1", "name": "V-type proton ATPase subunit H", "aln": "-------MG-ATKILMDSTHFNEIRSIIRSRSVAWDALARSEELSEIDASTAKALESILVKKNIGDGLSSSNNAHSGFKVNGKTLIPLIHLLSTSDNEDCKKSVQNLIAELLSSDKYGDDTVKFFQEDPKQLEQLFDVSLKGDFQTVLISGFN-VVSLLVQNGLHNVKLVEKLLKNNNLINILQNIEQMDTCYVCIRLLQELAVIPEYRDVIWLHEKKFMPTLFKILQRATDSQLATRIVATNSNHLGIQLQYHSLLLIWLLTFNPVFANELVQKYLSDFLDLLKLVKITIKEKVSRLCISIILQCCS-TRVKQHKKVIKQLLLLGNALPTVQSLSERKYSDEELRQDISNLKEILENEYQELTSFDEYVAELDSKLLCWSPPHVDNGFWSDNIDEFKKDNYKIFRQLIELLQAKVRNGDVNAKQEKIIIQVALNDITHVVELLPESIDVLDKTGGKADIMELLNHSDSRVKYEALKATQAIIGYTFK---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : : :*:..: * : :.: :* * . . :: * .. : .:::*:: ::. : : :: : *..:: . . *. : : . : . : ::: :. * . : : : : * . :* : : ::* : : . : . : *.: .:*:**: :: :*:*:*.* :. .: : . . * .::. ****:*: :: : : . . . : :: :.* :. *.::::.**:: *:. * * * :. *:*:***** :*: * * *** * . ** :* .:::.**:::: * .**:.. : :: ** *: . *. *.. *::: *** :*: : *.* *:*:** *.* :: :.: ", "identical_positions": 74, "similar_positions": 164, "identity": "14.37%" }, { "cls_id": "homologset.agr.SGD:S000006244", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2VCX1-1", "uniprot_id": "TIPRL_RAT", "id": "A2VCX1-1", "name": "TIP41-like protein", "aln": "--------------------------------------------------------------------------MMIHGFQS-----SHQDFSFGPWKLTASKTHIMKS-----------------ADVEKLAD-ELHMPSLPEMMFGDNVLRIQHG-SGFGIEFNATDALRCVNNYQGMLKVACAEEWQES--------------RTEGEHSKEVIKPYDWTYTTDYKGTLLGESLKLKVVPTTDHIDTEKLKAREQIKFFEEVLLFEDELHDHGVSSLSVKIRVMPSSFFLLLRFFLRIDGVLIRMNDTRLYHEADKTYMLREYTSRE--------SKIANLMHVPPSLFTEPNEISQYLPIKEAVCEKLVFPERIDPNPVDSE-SAPSE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH58-1", "uniprot_id": "TIPRL_MOUSE", "id": "Q8BH58-1", "name": "TIP41-like protein", "aln": "--------------------------------------------------------------------------MMIHGFQS-----SHQDFSFGPWKLTASKTHIMKS-----------------ADVEKLAD-ELHMPSLPEMMFGDNVLRIQHG-SGFGIEFNATDALRCVNNYQGMLKVACAEEWQES--------------RTEGEHSKEVIKPYDWTYTTDYKGTLLGESLKLKVVPTTDHIDTEKLKAREQIKFFEEVLLFEDELHDHGVSSLSVKIRVMPSSFFLLLRFFLRIDGVLIRMNDTRLYHEADKTYMLREYTSRE--------SKIANLMHVPPSLFTEPNEISQYLPIKEAVCEKLVFPERIDPNPVDSQ-STPSE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75663-1", "uniprot_id": "TIPRL_HUMAN", "id": "O75663-1", "name": "TIP41-like protein", "aln": "--------------------------------------------------------------------------MMIHGFQS-----SHRDFCFGPWKLTASKTHIMKS-----------------ADVEKLAD-ELHMPSLPEMMFGDNVLRIQHG-SGFGIEFNATDALRCVNNYQGMLKVACAEEWQES--------------RTEGEHSKEVIKPYDWTYTTDYKGTLLGESLKLKVVPTTDHIDTEKLKAREQIKFFEEVLLFEDELHDHGVSSLSVKIRVMPSSFFLLLRFFLRIDGVLIRMNDTRLYHEADKTYMLREYTSRE--------SKISSLMHVPPSLFTEPNEISQYLPIKEAVCEKLIFPERIDPNPADSQKSTQVE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QRY4-1", "uniprot_id": "F1QRY4_DANRE", "id": "F1QRY4-1", "name": "TIP41-like protein", "aln": "-----------------------------------------------------------------------MSSVISQGFQS-----SKQEFSFGPWIISATKTHIMKS-----------------KDIERLAE-AMQMPALPEMLFGDNVLRIWHS-DGFGIEFNAIDALRRVNNLQESVKVACAQEWQDS--------------RAQSEHSTEAVKRYDWTYTTDYRGTLIGEQTQMKVSPTAERIDMEKLKAREQIKFFEDVLLFEDELHDHGVSMISVKIRVMPSSFFLLLRFFLRVDGVLIRINDTRLYHEAGKKHMLREFSTRE--------SNMADLQHIPPAVYTDPNEIAPHLPLRLTECEKLEFPEGDAPAHTHTQ------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W5W6-1", "uniprot_id": "Q9W5W6_DROME", "id": "Q9W5W6-1", "name": "TIP41-like protein", "aln": "---------------------------------------------------------------------MSMEECFVPRLPV-----DSEFIQFHDWAIKYEKSHILKSSCQLGTAKCCPKDSADRCDLCHYQH-SLQLPHLPDMVFHKNRLVLQHK-DGATLEFCPMDALALVDNGKQPLEVACAQEWRET--------------RNE-QTMEEKFKPFDWTFTSTYQGTMN---EKVRSETTNQTLNKFKLMQRENIIFYHDLTLFEDELHDHGISVMSVRIRVMPSGFFILLRHFLRVDHVLIRMHDTRFHHEIENDFILKEYIHRE--------APCTELQNC-VAFWTNPDEMQEFVPVKSKQLHKLFFK-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12199-1", "uniprot_id": "TIP41_YEAST", "id": "Q12199-1", "name": "Type 2A phosphatase activator TIP41", "aln": "MSKRNTPPLRSSGINTIQINAAREMHAQTVRARRMPMPTSGITTPSVQPTAAPATPPRHICNNPNNPQCLHCGSVIIPSPRATLPLEDNPSISINDWTISSRKKPILNS-----------------QELDIWENEKLKGLTLPEMIFGNNYIRIENSKQHWSIEFNALDALKEVQLQDSGIRVAYSNDWINSKKRQNSTNGAQRFTNDVNDDSLNIIHKYDWTYTTRYKGTESSPESKFRLD-NDQKLPLDKLAVHDKILFYDDMILFEDELADNGISILNVKIRVMNERLLLLSRFFLRVDDVLVRVYDTRIYVEFDENVVIRESKEFEGKYQDVLAKHRLSQSHDPKAALRDSNWVAQNTPMIKRQCEIIQF------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : * :. *. *::* :: . :: **:*:* .* : : : . :** . *** *: . :.** :::* :: . : : .: :***:*: *:** :.: . : : ** :::* *:.:: ****** *:*:* :.*:**** . :::* *.***:* **:*: ***:: * : :::* * . : : :.: : *: . : * ", "identical_positions": 60, "similar_positions": 83, "identity": "15.31%" }, { "cls_id": "homologset.agr.SGD:S000006245", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q07205-1", "uniprot_id": "IF5_RAT", "id": "Q07205-1", "name": "Eukaryotic translation initiation factor 5", "aln": "-MSVNVNRSVSDQFYRYKMPRLIAKVEGKGNGIKTVIVNMVDVAKALNRPPTYPTKYFGCELGAQTQFDVKNDRYIVNGSHEANKLQDMLDGFIKKFVLCPECENPETDLHVNPKKQTIGNSCKACGYRGMLDTHHKLCTFILKNPPENSDIGTGKKEKE-KKNRKGK---DKENGSVST--------------SETPPPPPP-NEISPP---HAVEEEEDDDWGEDTTEEAQRRRMDEISDHAKGLTLSDDLERTVEERVNILFDFVK-KKKEEGIID--SSDKD-------IVAEAERLDVKAMGPL--VLTEVLFDEKIREQIKKYRRHFLRFCHNNKKAQRYLLHGLECVVAMHQAQLISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSKELAKEIRVKAEPFIKWLKEAEEESSGGEEEDEDENIEVVYSKTAS-----------VPKVETVKSDNKDDDIDIDAI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AVQ3-1", "uniprot_id": "A0A8I6AVQ3_RAT", "id": "A0A8I6AVQ3-1", "name": "Eukaryotic translation initiation factor 5", "aln": "-MSVNVNRSVSDQFYRYKMPRLIAKVEGKGNGIKTVIVNMVDVAKVLNRPPTYPTKYFGCELGAQAQFD--NDRYIVNGSHEANKLQDMLDGFIKKF-----CENPETDLHVNPKKQTIGNSCKACGYRGMLDTHQKLCTFILKNPPENSDIGTGKKEKE-KKNRKGK---DKENGSVST--------------SETPPPPPP-NEISPP---HAVEEEEDGDWGEDTTEEAQRRRMDESSDHAKGLTLSDDLERTVEERVNILFDFVK-KKKEEGIID--SSDKD-------IVAEAERLDVKAMGPL--VLTEVLFDEKIREQIKKYRRHFLRFCHNNKKAQWYLLHGLECVVAMHQVQLISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSKELAKEIHVKAEPFIKWLKEAEEESSGGEEEDEDENIEVVYSKTLS-----------VPKVETVKSDNKDDDIDIDAI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59325-1", "uniprot_id": "IF5_MOUSE", "id": "P59325-1", "name": "Eukaryotic translation initiation factor 5", "aln": "-MSVNVNRSVSDQFYRYKMPRLIAKVEGKGNGIKTVIVNMVDVAKALNRPPTYPTKYFGCELGAQTQFDVKNDRYIVNGSHEANKLQDMLDGFIKKFVLCPECENPETDLHVNPKKQTIGNSCKACGYRGMLDTHHKLCTFILKNPPENSDIGTGKKEKE-KKNRKGK---DKENGSVST--------------SETPPPPPP-NEISPP---HAVEEEEDDDWGEDTTEEAQRRRMDEISDHAKGLTLSDDLERTVEERVNILFDFVK-KKKEEGIID--SSDKE-------IVAEAERLDVKAMGPL--VLTEVLFDEKIREQIKKYRRHFLRFCHNNKKAQRYLLHGLECVVAMHQAQLISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSKELAKEIRVKAEPFIKWLKEAEEESSGGEEEDEDENIEVVYSKTAS-----------VPKVETVKSDNKDDDIDIDAI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55010-1", "uniprot_id": "IF5_HUMAN", "id": "P55010-1", "name": "Eukaryotic translation initiation factor 5", "aln": "-MSVNVNRSVSDQFYRYKMPRLIAKVEGKGNGIKTVIVNMVDVAKALNRPPTYPTKYFGCELGAQTQFDVKNDRYIVNGSHEANKLQDMLDGFIKKFVLCPECENPETDLHVNPKKQTIGNSCKACGYRGMLDTHHKLCTFILKNPPENSDSGTGKKEKE-KKNRKGK---DKENGSVSS--------------SETPPPPPPPNEINPPP--HTMEEEEDDDWGEDTTEEAQRRRMDEISDHAKVLTLSDDLERTIEERVNILFDFVK-KKKEEGVID--SSDKE-------IVAEAERLDVKAMGPL--VLTEVLFNEKIREQIKKYRRHFLRFCHNNKKAQRYLLHGLECVVAMHQAQLISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSKELAKEIRVKAEPFIKWLKEAEEESSGGEEEDEDENIEVVYSKAAS-----------VPKVETVKSDNKDDDIDIDAI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXK6-1", "uniprot_id": "IF5_DROME", "id": "Q9VXK6-1", "name": "Eukaryotic translation initiation factor 5", "aln": "MATVNVNRSVTDIFYRYKMPRLQAKVEGKGNGIKTVLVNMAEVARAIGRPATYPTKYFGCELGAQTLFDHKNERFVVNGSHDVNKLQDLLDGFIRKFVLCPECDNPETNLTVSAKNQTISQSCKACGFHGLLKVNHKVNTFIVKNPPSLNPAAQGSSLTEGKRSRKQKQKNDNADGSMTNNSLANNSGGESDGGNGTNQASQTEAEISAAIPEKTAKDDDDEGWSVDVSKEAIRARLQDLTDGAKGMTISDDYDKTEKERIDIFYELVK-DKRDKKQLDDVQTHKE-------LVIEAERLDIINKAPL--VLAELLFTENIIKDVQKNRPLLLRFTLNNPKAQRYLIGGVEQTVELHKGILMSKVAGIFKLFYDLDILDEAVILEWAQKVSKRHVSKNIAAEIHEKAMPFVLWLKNAEEESSESEEEEDDESEEDNYVSSAGQRGGQRVVQRGIPRAVAGDEDD-EDDVNIDDI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38431-1", "uniprot_id": "IF5_YEAST", "id": "P38431-1", "name": "Eukaryotic translation initiation factor 5", "aln": "-MSINICRDNHDPFYRYKMPPIQAKVEGRGNGIKTAVLNVADISHALNRPAPYIVKYFGFELGAQTSISVDKDRYLVNGVHEPAKLQDVLDGFINKFVLCGSCKNPETEIIIT-KDNDLVRDCKACGKRTPMDLRHKLSSFILKNPPD-SVSGSKKKKKAATASANVR----GGGLSISDIAQ-----------GKSQNAPSDGTGSSTP----QHHDEDEDELSRQIKAAASTLEDIEVKDDEWAVDMSEEAIRARAKELEVNSELTQLDEYGEWILEQAGEDKENLPSDVELYKKAAELDVLNDPKIGCVLAQCLFDEDIVNEIAEHNAFFTKILVT-PEYEKNFMGGIERFLGLEHKDLIPLLPKILVQLYNNDIISEEEIMRFGTKSSKKFVPKEVSKKVRRAAKPFITWLETAESD----DDEEDDE-------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*: *. * ******* : *****:******.::*:.::::.:.**..* .**** *****: :. ::*::*** *: ****:*****.** *.****:: :. *.: : ..***** : :. .:*: :**:****. . . .. . . . : : . *:: . : .. ... .:::: . : . * . : .* : :*:: :: :.::: ::.: .: : :: .*: : :* .**: : **:: ** *.* ::: : . : :: . : : :: *:* : :.: *:. :. *: :*: *::.* *: :. * **:.*.*::: ::: * **: **: **.: ::*::** ", "identical_positions": 105, "similar_positions": 158, "identity": "22.11%" }, { "cls_id": "homologset.agr.SGD:S000006247", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61513-1", "uniprot_id": "RL37A_HUMAN", "id": "P61513-1", "name": "Large ribosomal subunit protein eL43", "aln": "MAKRTKKVG-IVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRRAVGIWHCGSCMKTVAGGAWTYNTTSAVTVKSAIRRLKELKDQ-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61515-1", "uniprot_id": "RL37A_RAT", "id": "P61515-1", "name": "Large ribosomal subunit protein eL43", "aln": "MAKRTKKVG-IVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRRAVGIWHCGSCMKTVAGGAWTYNTTSAVTVKSAIRRLKELKDQ-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61514-1", "uniprot_id": "RL37A_MOUSE", "id": "P61514-1", "name": "Large ribosomal subunit protein eL43", "aln": "MAKRTKKVG-IVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRRAVGIWHCGSCMKTVAGGAWTYNTTSAVTVKSAIRRLKELKDQ-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NKH3-1", "uniprot_id": "RL37L_HUMAN", "id": "A6NKH3-1", "name": "Putative ribosomal protein eL43-like", "aln": "MAKCTKKVGGIVSKYRTHHGASLWKMVKEIEISQHTKYTCSFCGKTKMKRRAVKIRHCNSCMKTVAGSAWTYNTTSAVMVKSAIRRLKELKDQ-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A829-1", "uniprot_id": "D4A829_RAT", "id": "D4A829-1", "name": "Large ribosomal subunit protein eL43", "aln": "MAKRTKNVR-TVGKYRTCYGTSLRKMVKKVEISQHAKYTCSFCGKPKMKRRAVGSWRCGSCMKTVAGGAWTHNTTSAVTVKSAIRRLKELKDQQKPYHLRPAWPAINGLI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VMU4-1", "uniprot_id": "RL37A_DROME", "id": "Q9VMU4-1", "name": "Large ribosomal subunit protein eL43", "aln": "MAKRTKKVG-IVGKYGTRYGASLRKMVKKMEITQHSKYTCSFCGKDSMKRAVVGIWSCKRCKRTVAGGAWVYSTTAAASVRSAVRRLRETKEQ-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX25-1", "uniprot_id": "RL43A_YEAST", "id": "P0CX25-1", "name": "Large ribosomal subunit protein eL43A", "aln": "MAKRTKKVG-ITGKYGVRYGSSLRRQVKKLEIQQHARYDCSFCGKKTVKRGAAGIWTCSCCKKTVAGGAYTVSTAAAATVRSTIRRLREMVEA-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** **:* ..** . :*:** : **::** **::* ****** .:** .. * * :****.*:. .*::*. *:*::***:* : ", "identical_positions": 41, "similar_positions": 28, "identity": "37.27%" }, { "cls_id": "homologset.agr.SGD:S000006249", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GKE0-1", "uniprot_id": "A0A8I6GKE0_RAT", "id": "A0A8I6GKE0-1", "name": "", "aln": "MAANVGDQRTADWSSQYSMVAGASRENGMETPMHENPEWEKARQALASISKAGAAS-SSKASSSGPVASAQYVSQAEASALQQQQQQYYQWYQQYN-----YAYPYSYYYPMSMYQSYSSPSQYGMASSYGSATA---QQPSAPQHQGTLN------QPPVPGMDES-----MAYQASPQQLPAAQPPQP-------------------SNPQHGTHSLNNGPQSG---------TAPTTQHNQAGAPTGQTYGPHSYSEPAKP------KKGQQLWTRMKPAPGTGGLKFNIQKRPFAVTNQSFSSNSEGQHSGFGPQPNSEK-TQNHSGPSGRGN--LSGKPDDWPQDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSREPLPGQSWAWSLSCTTVAELPGLTREPVAESPKKKRWEAPSSLHPSRGAGSVTRGGGAQSQRGTPGAGGAGRARGSSFAKFGN-RNVFMKDNSSSSSTDSRSRSSSRSPTRHFR--------RSDSHSDS----DSSYSGNECHPVGRRNPPP-KGRG-----GRGAHMDRGRGR--AQRGKR--HDLAPTKRSRKK-------MAALECEDPERELKKQKRAARFQHGHSRRLRLEP-LVLQMSNLESSGADPD--------------------------WQELQIVGTCPDITKHYLRLTCAPDPSTVRPVAVLKKSLCMVKSHWKEK-QDYAFACEQMKSIRQDLTVQGIRTEFTVEVYETHARIALEKGDHEEFNQCQTQLKSLYAEN--LAGNVGEFTAYRILYYIFTKNSGDITTELAYLTRE----MKADPCVSHALALRAAWALGNYHRFFKLYCHAPCMSGYLVDKFADRERKAALKAMIKTYVALHSAAFCAVALPHPLHILVSLQLLCWSPLPIPCSHPWPSLLSSSATFSSRFSPTVLTSLLLVSCPVLPCTPVTSVWNLVYFPFSGSLPAARCCSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CBY3-1", "uniprot_id": "LENG8_MOUSE", "id": "Q8CBY3-1", "name": "Leukocyte receptor cluster member 8 homolog", "aln": "MAANVGDQRAADWSSQYSMVTGNSRENGMETPMHENPEWEKARQALASISKAGATS-SSKASSSGPVASAQYVSQAEASALQQQQQQYYQWYQQYN-----YAYPYSYYYPMSMYQSYGSPSQYGMASSYGSATA---QQPSAPQHQGTLN------QPPVPGMDES-----MAYQASPQQLPAAQPPQP-------------------SNSQHGTHSLSNGPQPG---------TAPSTQHSQAGAPTGQAYGPHSYSEPAKP------KKGQQLWTRMKPAPGTGGLKFNIQKRPFAVTSQSFSSNSEGQHSSFGPQPNSEN-TQNRSGPSGRGN--LSGKPDDWPQDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSREPLPG-----------------LTREPVAESPKKKRWEAPSSLHPSRGAGSVTRGGGAQSQRGTPGAGGAGRARGSSFTKFGN-RNVFMKDNSSSSSTDSRSRSSSRSPTRHFR--------RSDSHSDS----DSSYSGNECHPVGRRNPPP-KGRG-----GRGAHMDRGRGR--AQRGKR--HDLAPTKRSRKK-------MAALECEDPERELKKQKRAARFQHGHSRRLRLEP-LVLQMSNLESSGADPD--------------------------WQELQIVGTCPDITKHYLRLTCAPDPSTVRPVAVLKKSLCMVKSHWKEK-QDYAFACEQMKSIRQDLTVQGIRTEFTVEVYETHARIALEKGDHEEFNQCQTQLKSLYAEN--LAGNVGEFTAYRILYYIFTKNSGDITTELAYLTRE----MKADPCVAHALALRAAWALGNYHRFFRLYCHAPCMSGYLVDKFADRERKAALKAMIKTYVALHSAAFCAVALPRPLRILVSLQLLCWSPLPVPCS-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PV6-2", "uniprot_id": "LENG8_HUMAN", "id": "Q96PV6-2", "name": "Leukocyte receptor cluster member 8", "aln": "MAANVGDQRSTDWSSQYSMVAGAGRENGMETPMHENPEWEKARQALASISKSGAAGGSAKSSSNGPVASAQYVSQAEASALQQQQ--YYQWYQQYN-----YAYPYSYYYPMSMYQSYGSPSQYGMAGSYGSATP---QQPSAPQHQGTLN------QPPVPGMDES-----MSYQAPPQQLPSAQPPQP-------------------SNPPHGAHTLNSGPQPG---------TAPATQHSQAGPATGQAYGPHTYTEPAKP------KKGQQLWNRMKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNPEK-VQNHSGSSARGN--LSGKPDDWPQDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSREPLPG-----------------LTREPVAESPKKKRWEAASSLHPPRGAGSATRGGGAPSQRGTPGAGGAGRARGNSFTKFGN-RNVFMKDNSSSSSTDSRSRSSSRSPTRHFR--------RSDSHSDS----DSSYSGNECHPVGRRNPPP-KGRG-----GRGAHMDRGRGR--AQRGKR--HDLAPTKRSRKK-------MAALECEDPERELKKQKRAARFQHGHSRRLRLEP-LVLQMSSLESSGADPD--------------------------WQELQIVGTCPDITKHYLRLTCAPDPSTVRPVAVLKKSLCMVKCHWKEK-QDYAFACEQMKSIRQDLTVQGIRTEFTVEVYETHARIALEKGDHEEFNQCQTQLKSLYAEN--LPGNVGEFTAYRILYYIFTKNSGDITTELAYLTRE----LKADPCVAHALALRTAWALGNYHRFFRLYCHAPCMSGYLVDKFADRERKVALKAMIKTFRPALPVSYLQAELAFEG---EAACRAFLEPLGLAYTGP------DNSSIDCRLSLAQLSAF------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4QNR8-1", "uniprot_id": "LENG8_DANRE", "id": "A4QNR8-1", "name": "Leukocyte receptor cluster member 8 homolog", "aln": "MAANAAQQAPTQNWPYGNNSSG-------EGPVHENPEWEKARQALASISKSQNST--KPSTNQTTQQAGQYQAAVTDSSAMQQQQYYQQWYQQNQQQYAGYPYPYNYYYPMPPYGGPYPPGQYGVPGGYQTPTTPTGQAPSMPTMEDQSSNYPP--QPPPPATPQPPPQSPTSSDQPPPPPPPPIPPQPNAQYPRPPSQTPYSPNGVLPYSPTDSNPMMRGYNPGQIRPGYQGYQTPVYQPHQQQAPAPGLYGGAGRVDAKKPNNSNMNKGGQQLWQRMKQAPGTGAVKFNIPKRPYVMSNQNFPPGEQGPGLAPPTATNPSSGSTSATSSASTGG--AQTRPQDWPQAMKEYVQRCFTACESEEDKDRTEKMLKDLLQSRLQDGSAYTIDWNREPLPD------------------------LKPKQSRWEVMPQLS----------------QENSIGRGGATRGRGG--ARLGNYRNVFSQRSPSSSSSGS-SRSSSRSPSPHSRHRDRSRHHRSDSGSQS----DGSMSSDLRLSLTRRQQKGGRGRGAERERGRGAAGERGRGRGKANRGRRNMEDLASGVGKKRKG-----GNAGLDFHDPNREAKKQSRAARFHT----KLRTEP-LVLNINVFDLPNGTQEG-----------------------LSWDDCPIVGTCQDITKNYLRLTCAPDPSTVRPVPVLRKSLIAVKAHWKSN-QDYVYACEQMKSIRQDLTVQGVRTDFTVEVYETHARIALEKGDHEEFNQCQTQLKALYKDC--PSDNVGEFTAYRLIYYIFTKNSGDLTTELVYLTTE----LRADPCVAHALELRTAWALGNFHRFFRLYQKAPRMAAYLIDKFVERERNIALRAILKSFRPSVSVEYVQSSLAFPD---LDTCLAFLTGLGISFTPS------DPSKIDCKVSSASLTTS------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKP5-1", "uniprot_id": "Q9VKP5_DROME", "id": "Q9VKP5-1", "name": "PCI domain-containing protein", "aln": "MSDAMSAPPP------------------LIPQLQEMQQQQQQSANPAQLAQQWSNYAWYANQNAAYQQQYQQYYQYYVRYQQQQQQQVTSTVSTSN-APPGFSNALAAPPPLPSGPPPPPPPQIGQPPGQNKQQQQQQQQQQLQQQQQQQQQQQQQQQKNFGGIRFNLNLNQKRLAGAPNPLQQQQQQQHQQQ---------------QHQQQQQVMQLYNNNNSNKKKR-----KRNNKNKNFEQSTYSNPFANQTPATPQAP-------PPPIISASDVGVPINPDLSKPPPPLPLAIVAPTENPQHQKQQQQEHMAAQRAGEATSQTSNFKRPNSFQMASSDSWPNSLNQYVARCYSKCNTDLDKDQIDICLKGKIIAAANRNELWTRDWDNEPMPTVYSERD---------GIDVVLSNVPPPQQQRSNYFQKKQEQERERERDREADKSPAKGSTGIVNQFKQKGNQFNKASSSYGSHHSSSSKYSRSRSRSPSSSNSLKYSSKKRYSRSRSRSRSRSRSPRSRSCSRSSDASSPPARKIIRKSGSNESLNFIPLTANLSRKQQKMLMKKGKR-AAAMASAQMKKKDTPHFYSNQSSVGGAVDDDTARLQQRAARFSQQGSSSAKKSV-VAIASSPFGLTTAKNKKKMVQQHQQHQRSAFYEDTEAASGIDLLDLHIVGTCRDLEKSFLRLTKAPSPSEVRPVEVLTHSLVNVKGKWRAN-QDYHYACDQLKSIRQDLTVQGIRDQFTVEVYETHARIAMEKGDHEEFNQCQTQLKMLYMEIGGKNANALEFTAYRILYYIFTKNTLDITTVMRSITAD----QRENPVIAHALQFRSAWSLGNYCKLFSLYRTAPLMSGHMIEWFLERERKAALRVIIKSYRPNISVDYITKILAFDS---SEKCKEWLDTFSLPYAADG-------AQVDCKNAAAIAI--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12049-1", "uniprot_id": "THP3_YEAST", "id": "Q12049-1", "name": "Protein THP3", "aln": "-----------------------------------------------------------------------------------------------------------------------------MQNPYGHFTN---------------------------------------------------------------------------NTTEDREASSQGGPFG---------QSLNRPLDYAGSFPSLTYNNNNFIANQQP-----------------------SLPLPEPRLSWNNVNQVSNPLMVTPLPG---------------------------------------------------LQKRMNKNIKKKLPRVSKKASALSNGVSGNVMSN--------------------------------------------------------SNIVGHGAVGSASGWKVEMGGS----------------------------------------------------------------------------------------------------------------------------------DELERRKRRAERFSQGPSATTNSNDNLNEDFANLNAISSKSHQYD------------------------KKIHVVGRCQTLEKSYLRLTSEPNPDLIRPPNILQKMYCLLMDKYQSKTATYTYLCDQFKSMRQDLRVQMIENSFTIKVYQTHARIALENGDLGEFNQCQNRIMALFENPTIPKKSYSEFICYSVLYSMLTEDYPSISHLKLKLIDDGSSEILEDEHVKMIFELSDMKLVGNYHYFMKNYLKLHKFEKCLINSFLNLEKLIFLTIICKSYN-QVNLDFVKSEFNFNSIEETTNFLNEQNLTEFILNKQITDSNGKSSNIKILNTKGCRVQLIQNYMKSKKIDIKGQK--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : * : . . :.: : :* : : . : . . : :. . * * .. : : : ** ** . . : : . . . :** * : * :**** *.*. :** :* : : ::: : * : *:*:**:**** ** :. .**::**:******:*:** ******.:: *: : . ** .* ::* ::*:: .:: : : : : : : :**: :: * : ::: * : *: * : *:: : : . ", "identical_positions": 64, "similar_positions": 97, "identity": "6.5%" }, { "cls_id": "homologset.agr.SGD:S000006251", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYQ3-1", "uniprot_id": "SYFM_RAT", "id": "Q6AYQ3-1", "name": "Phenylalanine--tRNA ligase, mitochondrial", "aln": "MVCLAFIRAAHEHLYLVRKVSHVCRCHQHRAWGSRPAASQFAVQGAPGRVLELLGKSYPQD-DHTNLTQKVLSKVGRNLHNQKFHPLWLIKERVKEHFYQQYMGRSRTPLFSVYDQLSPVVTTWQNFDSLLIPADHPSRKKGDNYYLNRGHMLRAHTSAHQWDLLHAGLN-------AFLVVGDVYRRDQIDSQHYPVFHQLEGVRLFSKHELFAGVKDGESLQLFEESSR------------------------SAHKQETHTMEAVKLVEFDLKQVLTRLVTHLFG---------------DGLEVRWVDCYFPFTHPSFEMEINFRGEWLEVLGCGVMEQQLVNSAGAQDR--IGWAFGLGLERLAMVLYDIPDIRLFWSEDERFLKQFRLSDINQSVKFQRWFFQEERATGIQRKMGRQLCPFSKYPAVFNDISFWLPS-----ENYTENDFYDIVRTVGGDLVEKVDLIDKFEHPKTHRTSHCYRITYRHMERTLSQREVSSVHQAVQEAAVQLLGVEGRF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99M01-1", "uniprot_id": "SYFM_MOUSE", "id": "Q99M01-1", "name": "Phenylalanine--tRNA ligase, mitochondrial", "aln": "MVCLALVRAAYEHIYLVRKVSHACRCHQHRAWSSKPAASQSAVQGAPGSVLEILGKSYPQD-DHTNLTQKVLSKVGRNLHNQKFHPLWLIKERVKEHFYQQYMVRSRTPLFSVYDQLPPVVTTWQNFDSLLIPADHPSRKKGDNYYLNRAHMLRAHTSAHQWDLLHAGLN-------AFLVVGDVYRRDQIDCQHYPVFHQLEGVRLFSKHELFAGVKDGESLQLFEEGSR------------------------SAHKQETHTMEAVKLVEFDLKQVLTRLVTHLFG---------------DGLEVRWVDCYFPFTHPSFEMEINFRGEWLEVLGCGVMEQQLVNSAGAQDR--IGWAFGLGLERLAMVLYDIPDIRLFWSEDERFLKQFLLSDINQSVKFQ---------------------PLSKYPAVFNDISFWLPS-----ENYTENDFYDIVRTVGGDLVEKVDLIDKFEHPKTHRTSHCYRITYRHMERTLSQREVGNVHQAVQEAAVQLLGVEGRF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95363-1", "uniprot_id": "SYFM_HUMAN", "id": "O95363-1", "name": "Phenylalanine--tRNA ligase, mitochondrial", "aln": "MVGSALRRGAHAYVYLVSKASHISRGHQHQAWGSRPPAAECATQRAPGSVVELLGKSYPQD-DHSNLTRKVLTRVGRNLHNQQHHPLWLIKERVKEHFYKQYVGRFGTPLFSVYDNLSPVVTTWQNFDSLLIPADHPSRKKGDNYYLNRTHMLRAHTSAHQWDLLHAGLD-------AFLVVGDVYRRDQIDSQHYPIFHQLEAVRLFSKHELFAGIKDGESLQLFEQSSR------------------------SAHKQETHTMEAVKLVEFDLKQTLTRLMAHLFG---------------DELEIRWVDCYFPFTHPSFEMEINFHGEWLEVLGCGVMEQQLVNSAGAQDR--IGWAFGLGLERLAMILYDIPDIRLFWCEDERFLKQFCVSNINQKVKFQ---------------------PLSKYPAVINDISFWLPS-----ENYAENDFYDLVRTIGGDLVEKVDLIDKFVHPKTHKTSHCYRITYRHMERTLSQREVRHIHQALQEAAVQLLGVEGRF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O16129-1", "uniprot_id": "SYFM_DROME", "id": "O16129-1", "name": "Probable phenylalanine--tRNA ligase, mitochondrial", "aln": "-MLLTLR---------VQGARHWLKSTRCLASSAAPAKSPSSPP-----QLEVSGSTYATD-GWTNVTPKILSYVGANKHLQTDHPLSIIRQRIVNYFYGAYRNQRGNPLFSVYDQMNPVVTVQQNFDNLLIPADHVSRQKSDCYYINQQHLLRAHTTAHQVELISGGLD-------NFLVVGEVYRRDEIDSTHYPVFHQADAVRLVTKDKLFE---RNPGLELFEETWSGTL--------ADPKLILPSSKFMDQTKQPCHTLEAVKLMEHEMKHVLVGLTKDLFG---------------PRIKYRWVDTYFPFTQPSWELEIYFKDNWLEVLGCGIMRHEILQRSGVHQS--IGYAFGVGLERLAMVLFDIPDIRLFWSNDSGFLSQFSEKDLHNLPKYK---------------------PISHYPQCTNDLSFWLPQDIEVDAGFSPNDFYDLVRSVAGDMVEQISLVDKFKHPKTGKSSVCFRIVYRHMERTLTQAEVNEIHKQIASASVDSFNVQIR-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08425-1", "uniprot_id": "SYFM_YEAST", "id": "P08425-1", "name": "Phenylalanine--tRNA ligase, mitochondrial", "aln": "---------------MFLNRMMKTRTGLYRLYSTLKVP-----------HVEINGIKYKTDPQTTNVTDSIIKLTDRSLHLKESHPVGILRDLIEKKLNSVDN------TFKIFNNFKPVVTTMENFDSLGFPKDHPGRSKSDTYYINETHLLRTHTSAHELECFQKIRNDSDNIKSGFLISADVYRRDEIDKTHYPVFHQMEGATIWKRTKADVGVKEPMYIEKIREDIRQVENLLNKENVKITVDDDTIPLKENNPKQEYMSDLEVDLCSQHLKRSIELIVSEVFNKKISSMIKNKANNTPKELKVRWINAYFPWTAPSWEIEVWWQGEWLELCGCGLIRQDVLLRAGYKPSETIGWAFGLGLDRIAMLLFEIPDIRLLWSRDERFSRQFSKG---LITSFK---------------------PYSKHPGSFRDVAFWLPEDKPDIHQVHENDLMEIIRNIAGDLVESVKLVDSFTHPKTGRKSMCYRINYQSMDRNLTNAEVNTLQDMVCSKLVKEYSVELR-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .: :*: * .* * :*:* .::. .. . * : **: :::: : : : *.::::: ****. :***.* :* ** .*.*.* **:*. *:**:**:**: : : : **: .:*****:** ***:*** :.. : .: : :: :.: . ** : *.* . .:*: : : .:*. :: **:: ***:* **:*:*: ::.:***: ***::.:::: :* : **:***:**:*:**:*::******:*..*. * ** .:: * *::* .*::****. **: :::*.:.**:**.:.*:*.* **** :.* *:** *: *:*.*:: ** ::. : . *. .*: * ", "identical_positions": 129, "similar_positions": 147, "identity": "24.52%" }, { "cls_id": "homologset.agr.SGD:S000006252", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ABT4-1", "uniprot_id": "D4ABT4_RAT", "id": "D4ABT4-1", "name": "NADPH-dependent diflavin oxidoreductase 1", "aln": "-MQVPQLLVLFGSQTGTAQDEAERLGREARRRRLGCRVQALDSYSVANLIREPLVIFVCATTGQGDPP--------DNMKNFWRFIFRKSLPSTSLCQMDFAVLGLGDSSYAKFNFVAKKLHRRLL-QLGGNALVPPCLGDDQHELGP--------DAAIDPWVGDLWEKIMTMYPVPLDIPEIPHGVPLPSKFIFQFLQEVPSIGAEELNLASSAPQTPPSELQPFLAPVVTNQRVTGPQHFQDVRLMEFD-ITESNISFAAGDVVLILPSNSEAHTKQFCQLL-----CLDPNQFFTLKPREPGVPYPPGLPQHCTVWHLVSQYLDIASVPRRSFFELLACLSPHALERE-----------KLLEFSSARGQEELWEYCNRPRRTILEVLCDFPHTAGAIPPDYLLDLIPRIRPRAFSIASSLLAHPRRLQILVAVVKYQTRLKEPRRGLCSSWLASLTPGQAGPVRVPLWVRPGSLVFPKTPGTPIIMVGPGTGVAPFRAAIQERVAHGQMGN-----VLFFGCRQRDQDFYWQTEWQELEQRGCLTLVTAFSREQAQK---VYVQHRLRELGPLVWELLDGQGAYFYLAGNAKYMPTDVSEALTAIFQEEGRLS-TTDAAAYLARLQQTLRFQTETWA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AI05-1", "uniprot_id": "NDOR1_MOUSE", "id": "A2AI05-1", "name": "NADPH-dependent diflavin oxidoreductase 1", "aln": "-MQVPQLLVLFGSQTGTAQDEAERLGREARRRRLGCRVQALDSYSVANLIREPLVIFVCATTGQGDPP--------DNMKNFWRFIFRKSLPSSSLCQMDFAVLGLGDSSYAKFNFVAKKLHRRLL-QLGGSALLPPCLGDDQHELGP--------DAAIDPWVGDLWEKIMVMYPVPLDIPEIPHGVPLPSKFIFQFLQEVPSIGAEELNIASSAPQTPPSELQPFLAPVITNQRVTGPQHFQDVRLIEFD-ITDSNISFAAGDVVFILPSNSEAHTQQFCQVL-----CLDPNQFFTLKPREPGVPDPPGLPQPCTVWNLVSQYLDIASVPRRSFFELLACLSQHALERE-----------KLLELSSARGQEELWEYCSRPRRTILEVLCDFPHTAGAIPPDYLLDLIPRIRPRAFSIASSLLAHPRRLQILVAVVKYQTRLKEPRHGLCSSWLASLNPGQAGPVRVPLWVRPGSLVFPKTPDTPIIMVGAGTGVAPFRAAIQERVAHGQTGN-----FLFFGCRQRDQDFYWQTEWQKLEQKGWLTLVTAFSREQEQK---VYVQHRLRELGPLVWELLDGQGAYFYLAGNAKYLPTDVSEALMSIFQEEGRLS-TADASAYLARLQQTLRFQTETWA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHB4-1", "uniprot_id": "NDOR1_HUMAN", "id": "Q9UHB4-1", "name": "NADPH-dependent diflavin oxidoreductase 1", "aln": "-MPSPQLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCATTGQGDPP--------DNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLL-QLGGSALLPVCLGDDQHELGP--------DAAVDPWLRDLWDRVLGLYPPPPGLTEIPPGVPLPSKFTLLFLQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRVTGPSHFQDVRLIEFD-ILGSGISFAAGDVVLIQPSNSAAHVQRFCQVL-----GLDPDQLFMLQPREPDVSSPTRLPQPCSMRHLVSHYLDIASVPRRSFFELLACLSLHELERE-----------KLLEFSSAQGQEELFEYCNRPRRTILEVLCDFPHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHPSRLQILVAVVQFQTRLKEPRRGLCSSWLASLDPGQ-GPVRVPLWVRPGSLAFPETPDTPVIMVGPGTGVAPFRAAIQERVAQGQTGN-----FLFFGCRWRDQDFYWEAEWQELEKRDCLTLIPAFSREQEQK---VYVQHRLRELGSLVWELLDRQGAYFYLAGNAKSMPADVSEALMSIFQEEGGLC-SPDAAAYLARLQQTRRFQTETWA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PFP6-1", "uniprot_id": "NDOR1_DANRE", "id": "Q6PFP6-1", "name": "NADPH-dependent diflavin oxidoreductase 1", "aln": "-MSGHTVLVLYGSQTGTAQDTAERIGRQAQRRRLRVKVEALDTYNVVNLISESLVVFVCATTGQGDPP--------DNMKKFWRFLFRKSLPADSLSRLDCAVLGLGDSSYPKFNFVAKKLHKRLL-QLGANMLLPVGLADDQHDLGP--------DGVIDPWLLSFWQKTLSLYPPPAGLAPLREEDKLPPRYIFHFLSEVPNKLTEHLQTVDN--KSSPTPLRPFPAPLVFNQRVTHTAHFQDVRHIEFD-ITGSNIEFSAGDTVMMRPCNTSEDVEQLCQLL-----KLDPESYFTLTPTDSSTEVPARLPQPCSIRFLLEHFLDISAVPRRSFFELLATFATDELEQE-----------KLLEFSSAAGQDTLHSYCNRPRRTALEVLTDFPHTTAELSIGRLLDLFPEIQPRSFSIASSLLEHPNRIQILLAVVKYKTMLVKPRKGLCSSWLASLDPSK-GDVYVPLWVKKGSLKFPQDPESPVIMVGPGTGVAPFRSAIQERVAQGKMAN-----VLFFGCRSESKDFYCGSEWQEKVQAGQMILVTAFSRDQEDK---VYVQHRVKEQGKLLWDLIAKKNAFFYIAGNAKQMPTSVCDALKAVFQKEGGMS-ENQAQEMLDGMEKNGRFQSETWS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSJ5-1", "uniprot_id": "Q9VSJ5_DROME", "id": "Q9VSJ5-1", "name": "NADPH-dependent diflavin oxidoreductase 1", "aln": "----MRLLVLYGSQTGTAQDVAEQIWRESHQLGFQGPVLPFDEYDMTKLIEERLVVFVVATTGDGVEP--------DNMKLAWRFLLKRSLPAQSLQGMQFACLGLGDSSYPKFNYAAKKLSKRLQ-NLGANSVCPVGLCDDQHDYGH--------LGVSLSWTKDLWTALKGISG--LDESKLSNSHQTTVKWSVKELPKDSQIAPMD-NLLWSQKQTAHS------FKILDNQRTTAVDHFQDVRFLRLQ-CQTEDLSWEPGDVLDVQPQNSDEAVQTFFDLIREHSLNFDESTIVEVSSAHQDMPLPIAYSNPLSLLQAAKFVWDLSAKPRQRFLEVLAQNCCDEMEKE-----------KLLEFSSAEGIDDLVAYVNRPRRNLLEVLEDFRHATSSLTLQQLFEMMPLIQPRSFSIASDVSALS--LDLLVAVVEYKTIMHTPRLGLCSNWLKTLKSGT----ELSGVVKRGTMVWPKDLSIPLIMVGPGTGIAPFRSIIQNRLYAQSKGATIGPLVVFFGCRNKAADFHFGNDFSTWTDAKQVEAHTAFSRDQDQK---VYVQHLIAKNGAHLARLIKDLNAYIYVAGNSNNMPKSVKEAFIEILDG---------DADYVELMIKQRRYQEETWA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12181-1", "uniprot_id": "NDOR1_YEAST", "id": "Q12181-1", "name": "NADPH-dependent diflavin oxidoreductase 1", "aln": "MSSSKKIVILYGSETGNAHDFATILSHRLHRWHFSHTFCSIGDYDPQDILKCRYLFIICSTTGQGELPRNVNALKGERPVTFWSFLKRKNLPSNLLNHIQTAMLGLGDSSYPKFNYGIRKLHQRIVTQLGANELFDRLEADDQAMAGSNKGTGLGIESVYFEYEKKVLSFLLSKYPNRKVNGQIIKREELDPEVYLEPASYLQLSDEHANEKFTSTKVIFEGDESLKVGRVNINKRITSEGHFQDVRQFKFSNVDKIQENYEPGDTVTIYPCNTDEDVSRFLANQS--HWLEIADKPLNFTSGVPNDLKDGGLVRPMTLRNLLKYHCDFMSIPRTSFFLKIWTFATDVTKMERGQEQLNDQREKLRQFATDQDMQDLYDYCNRPRRSILEVLEDF--ISVKLPWKYVLDYLPIIKPRYYSISSGPGDPN--IELTVAIVKYKTILRKIRRGICTNYIARLQEGE----QIRYKLQNNHIIKKEFLNKPMILVGPGVGLAPLLSVVKAEISKD--------IKLLFGCRYKDKDYIYKDMLEDWFRKGKIALHSSFSRDEENSPGVKYVQDYLWRLGEEITNLVVNKDAVFFLCGSSGKMPIQVRLTFIEMLKKWGNFSDEETAKKYLKEMEKSDRYIQETW-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::*:**:**.*:* : : :. :: : . .:. * .:: :.:: :***:* * :. * *: ::.**: * :: * ********.***: :** :*: :**.. : *** * .. : .. : . . . : *:* * ****** :.:. .: .**.: : * *: .. : . . . . . . :: . *: : ** *: : . . : * ** :::: . : * * .****. **** ** : :. ::: :* *:** :**:*. ::: :*:*:::* : * *:*:.:: * . : :: . : : *:*:**.*.*:**: : :: .: ::**** . *: . : .:***:: :. ***. : . * : *: .* :::.*.: :* .* :: ::. : : : *: *** ", "identical_positions": 114, "similar_positions": 172, "identity": "17.76%" }, { "cls_id": "homologset.agr.SGD:S000006255", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q95RC0-1", "uniprot_id": "NA30A_DROME", "id": "Q95RC0-1", "name": "N-alpha-acetyltransferase 30A", "aln": "-----------MADAQAAAAGKKKYKNKKNSAEKNPNHNPNSSGQVEAQTPSNGHVQHQEEEATEDQEPAQELRGLLKKMHLCNGHGHKEQEARPLGEVVNGHAHGHSNNNHIRCTSGSSNNNNSTHNNNSVDSSNNNRKQRREGGDGGGSDSNSLKPEEKPITATSKTTANIHPTTTTDPKPKVSEDVAVEQGVHVATGSGHSREQERKQPPSDYAEGATPTITAQLQLPEPAISAD-EIVYKEYEAEHQMHDIMRLIQAELSEPYSIYTYRYFIYNWPKLCFLASHD-----NQYVGAIVCKLDMHMN-VRRGYIAMLAVRKEYRKLKIGTTLVTKAIEAMLADNADEVVLETEMRNQPALRLYENLGFVRDKRLFRYYLNGVDALRLKLWFR-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IRH2-1", "uniprot_id": "Q8IRH2_DROME", "id": "Q8IRH2-1", "name": "", "aln": "-----------MGDALPEAVLIQKELSDKDSQEK---------------------------------------------MDLVTKN-----------------------------------------------------------------------------------------------LPLFAEKIVLPE-------------------------------------NDTAAKSE-GIHFCVFHDESQLKVLMGLIDKELSEPYSIYTYRYFVYNWPDLCFFALDG-----DRYVGVIVCKLEAKRDGYLQGYIAMLAVDAEYRKRGIGRALSEMAIDAMAIRDAAMIVLETELSNKPALALYQSLGFIRERRFLRYYLNGMDAFHLKLMLHDFIDSSLNEV-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03503-1", "uniprot_id": "NAA30_YEAST", "id": "Q03503-1", "name": "N-alpha-acetyltransferase 30", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEIVYKPL-DIR-----NEEQFASIKKLIDADLSEPYSIYVYRYFLNQWPELTYIAVDNKSGTPNIPIGCIVCKMDPHRNVRLRGYIGMLAVESTYRGHGIAKKLVEIAIDKMQREHCDEIMLETEVENSAALNLYEGMGFIRMKRMFRYYLNEGDAFKLILPLTEKSCTRSTFLMHGRLAT", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8CES0-1", "uniprot_id": "NAA30_MOUSE", "id": "Q8CES0-1", "name": "N-alpha-acetyltransferase 30", "aln": "-----------MAEVPPGPSSLLPPPAPAAPAAAELRCPFPAGAALACCS--------EDEEDDEEHEGG-CGSPAGGEAAT-SAKARSCLRCPQLPPEQQQQQLNGLIGPELRHLRAAATLKSKVLSAAEAAA----PDGASKVTATKGAEGHPGERPPHSVPNNARTALPGRSE-AAAAAAGAASDPAAARNGLVEGTEQQEEEEMDEQVRLLSSSLTTGCSLRSSQGREAEPGEDRTIRYVRYESELQMPDIMRLITKDLSEPYSIYTYRYFIHNWPQLCFLAMVG-----EECVGAIVCKLDMHKKMFRRGYIAMLAVDSKYRRNGIGTNLVKKAIYAMVEGDCDEVVLETEITNKSALKLYENLGFVRDKRLFRYYLNGVDALRLKLWLR-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZWS6-1", "uniprot_id": "D3ZWS6_RAT", "id": "D3ZWS6-1", "name": "N-alpha-acetyltransferase 30", "aln": "MASSLGCVASRMAEVPPGPSSLLPPPAPAAPAAAELRCPFPAGAALACCS--------EDEEDDEEHEGG-CGSPAGGEAAT-AAKARSCLRCPQLPQEQQQQ-LNGLIGPELRHLRAAGTLKSKVLSAAEAAA----PDGAPKVTATKGAEGHPGERPPHSVPNNARTALPGRPEAAAAAAAGAASDPATSRNGLVEGNEQEEEE--DEQVRLLSSSLTTGCSLSSSLGREAEPGEDRTIRYVRYESELQMPDIMRLITKDLSEPYSIYTYRYFIHNWPQLCFLAMVG-----EECVGAIVCKLDMHKKMFRRGYIAMLAVDSKYRRNGIGTNLVKKAIYAMVEGDCDEVVLETEITNKSALKLYENLGFVRDKRLFRYYLNGVDALRLKLWLR-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q147X3-1", "uniprot_id": "NAA30_HUMAN", "id": "Q147X3-1", "name": "N-alpha-acetyltransferase 30", "aln": "-----------MAEVPPGPSSLLPPPAPPAPAAVEPRCPFPAGAALACCS--------EDEEDDEEHEGGGSRSPAGGESATVAAKGHPCLRCPQPPQE-QQQ-LNGLISPELRHLRAAASLKSKVLSVAEVAATTATPDGGPRATATKGAGVHSGERPPHSLSSNARTAVP------SPVEAAAASDPAAARNGLAEGTEQEEEEE-DEQVRLLSSSLTADCSLRSPSGREVEPGEDRTIRYVRYESELQMPDIMRLITKDLSEPYSIYTYRYFIHNWPQLCFLAMVG-----EECVGAIVCKLDMHKKMFRRGYIAMLAVDSKYRRNGIGTNLVKKAIYAMVEGDCDEVVLETEITNKSALKLYENLGFVRDKRLFRYYLNGVDALRLKLWLR-----------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * *: : ** :********.****: :**.* ::* . : :* ****:: : . :***.**** ** *. * ** * .. ::****: *..** **:.:**:* :*::***** **::* * : ", "identical_positions": 62, "similar_positions": 37, "identity": "15.05%" }, { "cls_id": "homologset.agr.SGD:S000006256", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54879-1", "uniprot_id": "HMGB3_MOUSE", "id": "O54879-1", "name": "High mobility group protein B3", "aln": "MAKGDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSSKEKSKFDEMAKADKVRYDREMKDYGP---AKGGKKKKDPNAPKRPPSGFFLFCSEF-RPKIKSTNPGISIGDVAKKLGEMWNNLSDNEKQPYVTKAAKLKEKYEKDVADYKSKG-KFDGAK--GPAKVARKKVEEEEEEEEEEEEEEEEEEDE------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15347-1", "uniprot_id": "HMGB3_HUMAN", "id": "O15347-1", "name": "High mobility group protein B3", "aln": "MAKGDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEKSKFDEMAKADKVRYDREMKDYGP---AKGGKKKKDPNAPKRPPSGFFLFCSEF-RPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQPYITKAAKLKEKYEKDVADYKSKG-KFDGAK--GPAKVARKKVEEEDEEEEEEEEEEEEEEDE------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N808-1", "uniprot_id": "A0A8M1N808_DANRE", "id": "A0A8M1N808-1", "name": "High mobility group protein B2", "aln": "MGK-DPNKPRGKTSSYAFFVQTCREEHKKKNPGTSVNFSEFSKKCSERWRTMSSKEKGKFEEMAKTDKVRYDREMKNYVPPKGAKGGKKKKDPNAPKRPPSAFFVFCSDH-RPKVKGDNPGISIGDIAKKLGEMWSKLSPKEKSPYEQKAMKLKEKYEKDVAAYRAKGGKPDGAKKGGPGRPAGKKAEADDDDDEDEDEEDEEEEDEEDED-------------------DDDE---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6A2H1-1", "uniprot_id": "A0A8I6A2H1_RAT", "id": "A0A8I6A2H1-1", "name": "", "aln": "------------MSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKCEDMAKADKARYEREMKTYIPHK-GETKKKFKDPNAPKRPPSAFFLFCSEY-RPKIKGEHPGLSIGDVAKKLGEMWTNTAADDKQPYGKMAAKLKEKYEKDIAAYRAKGKP-DAAKK-GVVKAEKSKKKKEEEDDEEDEEDEEEEEEKEDEDEEEE---------------DDDE---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63158-1", "uniprot_id": "HMGB1_MOUSE", "id": "P63158-1", "name": "High mobility group protein B1", "aln": "MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPK-GETKKKFKDPNAPKRPPSAFFLFCSEY-RPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKP-DAAKK-GVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEED---------------DDDE---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09429-1", "uniprot_id": "HMGB1_HUMAN", "id": "P09429-1", "name": "High mobility group protein B1", "aln": "MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPK-GETKKKFKDPNAPKRPPSAFFLFCSEY-RPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKP-DAAKK-GVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEED---------------DDDE---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B2RPK0-1", "uniprot_id": "HGB1A_HUMAN", "id": "B2RPK0-1", "name": "High mobility group protein B1-like 1", "aln": "MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHSDASVNFSEFSNKCSERWKTMSAKEKGKFEDMAKADKTHYERQMKTYIPPK-GETKKKFKDPNAPKRPPSAFFLFCSEY-HPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPGEKKAAKLKEKYEKDIAAYQAKGKP-EAAKK-GVVKAEKSKKKKEEEEDEEDEEDEEEE----DEEDEED---------------DDDE---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GJ73-1", "uniprot_id": "A0A8I6GJ73_RAT", "id": "A0A8I6GJ73-1", "name": "", "aln": "MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPK-GETKKKFKDPNAPKRPPSAFFLFCSEY-RPKIKGEHPGLSIGDVVKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGMQRKRGWS-RLRRARKRRKRKTTRRMKRMRKRRKKMKMKMKKKMMMMNKLVLVGAQHKLVIYGDSSLVFGFFFLFLFLFFFLLVFFFHLQLSLMQLIRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "X1WFI9-1", "uniprot_id": "X1WFI9_DANRE", "id": "X1WFI9-1", "name": "", "aln": "MGK-DPRKPRGKMSSYAYFVQTCREEHKKKHPEASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKQDKVRYEREMKNYIPPK-GEKKKRFKDPNAPKRPPSAFFIFCGDY-RPKIKGENPGLSIGDIAKKLGEMWNSSSAEVKQPYEKKAAKLKEKYDKDIALYRTKGIA-------GFSKKEGGEDDEEDEDDDEEEDDEEEE---------------------------DDE---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P30681-1", "uniprot_id": "HMGB2_MOUSE", "id": "P30681-1", "name": "High mobility group protein B2", "aln": "MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDLAKSDKARYDREMKNYVPPK-GDKKGKKKDPNAPKRPPSAFFLFCSEN-RPKIKIEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKS-EAGKK-GPGRPTGSKKKNEPEDEEEEEEEEEEEDDEEEEE--------------------DEE---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52925-1", "uniprot_id": "HMGB2_RAT", "id": "P52925-1", "name": "High mobility group protein B2", "aln": "MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDLAKSDKARYDREMKNYVPPK-GDKKGKKKDPNAPKRPPSAFFLFCSEH-RPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKS-EVGKK-GPGRPTGSKKKNEPEDEEEEEEEEDDEDEEEEDE--------------------DEE---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26583-1", "uniprot_id": "HMGB2_HUMAN", "id": "P26583-1", "name": "High mobility group protein B2", "aln": "MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYVPPK-GDKKGKKKDPNAPKRPPSAFFLFCSEH-RPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKS-EAGKK-GPGRPTGSKKKNEPEDEEEEEEE-EDEDEEEEDE--------------------DEE---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZS25-1", "uniprot_id": "D3ZS25_RAT", "id": "D3ZS25-1", "name": "High mobility group protein B2", "aln": "MGKGDPNKPRGKMSLYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDLAKSDKARYDREMKNYVPPK-GNKKGKKKDPNAPKRPPSAFFLFCSEH-RPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKS-EVGKK-GPGRPTGSKKKNEPEDEEEEEEE-DGEDEEEEDE--------------------DEE---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0L511-1", "uniprot_id": "A0ABK0L511_RAT", "id": "A0ABK0L511-1", "name": "High mobility group protein B4", "aln": "MGKKVQLRPKVNVSSYIHFMINFRNKFKEQQPNTYLTFNEFSRRCSEKWRSISKNEKAKFEAIAKLDKARYQEEMMNYVGKR---RKRRKRDPLAPRKPPSSFLLFSLDH-FAKLKQENPNWTVVQVAKAAGKMWSMITDVDKRPYEQKAAIMRAKYFQEREAYLSQCQN---------SKINLQGSSKSS----LKE---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P8W9-1", "uniprot_id": "HMGB4_MOUSE", "id": "Q6P8W9-1", "name": "High mobility group protein B4", "aln": "MGEKDQLRPKVNVSSYIHFMLNFRNKFKEQQPNTYLGFKEFSRKCSEKWRSISKHEKAKYEALAELDKARYQQEMMNYIGKR---RKRRKRDPKAPRKPPSSFLLFSRDH-YAMLKQENPDWTVVQVAKAAGKMWSTTDEAEKKPYEQKAALMRAKYFEEQEAYRNQCQG---------RKGNFLESAKTS----LKQ---------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WW32-1", "uniprot_id": "HMGB4_HUMAN", "id": "Q8WW32-1", "name": "High mobility group protein B4", "aln": "MGKEIQLKPKANVSSYVHFLLNYRNKFKEQQPNTYVGFKEFSRKCSEKWRSISKHEKAKYEALAKLDKARYQEEMMNYVGKR---KKRRKRDPQEPRRPPSSFLLFCQDH-YAQLKRENPNWSVVQVAKATGKMWSTATDLEKHPYEQRVALLRAKYFEELELYRKQCNA---------RKKYRMSARNRCRGKRVRQS--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JW93-1", "uniprot_id": "A0A0G2JW93_RAT", "id": "A0A0G2JW93-1", "name": "High mobility group protein B4", "aln": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPR---RERRRRDPDAPRKPPSSFLLFSQDH-FDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQR---------GE--------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LF85-1", "uniprot_id": "A0ABK0LF85_RAT", "id": "A0ABK0LF85-1", "name": "High mobility group protein B4", "aln": "MGIDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWRTISKKEKKKYEALAKRDKDRYQREMRNYSGPR---RERRRRDPDAPRKPPSSFLLFSQDH-FDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQR---------GE--------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LC80-1", "uniprot_id": "A0ABK0LC80_RAT", "id": "A0ABK0LC80-1", "name": "High mobility group protein B4", "aln": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYTGPR---RERRRRDPDAPRKPPSSFLLFSQDH-FDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQR---------GK--------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LC67-1", "uniprot_id": "A0ABK0LC67_RAT", "id": "A0ABK0LC67-1", "name": "High mobility group protein B4", "aln": "MGKDSKVRPKVNVSPYVHFMMDFRNQMREQQPNIYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPR---RERRRRDADAPRKPPSSFLLFSQDH-FDEIKEQHPNWTVGQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQR---------GE--------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0M042-1", "uniprot_id": "A0ABK0M042_RAT", "id": "A0ABK0M042-1", "name": "High mobility group protein B4", "aln": "MGKDSKVRPKVNVSPYVHFMMDFRNQMREQQPNIYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYTGPR---RERRRRDADAPRKPPSSFLLFSQDH-FDEIKEQHPNWTVGQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQR---------GE--------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZLC5-1", "uniprot_id": "A0A8I5ZLC5_RAT", "id": "A0A8I5ZLC5-1", "name": "High mobility group protein B4", "aln": "MGKDSKVRPKVNVSPYVHFMMDFRNQMREQQPNIYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYTGPR---RERRRRDADAPRKPPSSFLLFSQDH-FEEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQR---------GE--------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LY90-1", "uniprot_id": "A0ABK0LY90_RAT", "id": "A0ABK0LY90-1", "name": "High mobility group protein B4", "aln": "MGKDSKVRPKVNVSPYVHFMMDFRNQMREQQPNIYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPR---RERRRRDPDAPRKPPSSFLLFSQDH-FEEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYQQCQR---------GK--------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11632-1", "uniprot_id": "NHP6A_YEAST", "id": "P11632-1", "name": "Non-histone chromosomal protein 6A", "aln": "-------------------MVTPREPKKR--------------------------------------------------------TTRKKKDPNAPKRALSAYMFFANEN-RDIVRSENPDITFGQVGKKLGEKWKALTPEEKQPYEAKAQADKKRYESEKELYNATLA--------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q06943-1", "uniprot_id": "HMGZ_DROME", "id": "Q06943-1", "name": "High mobility group protein Z", "aln": "------------------------------------------------------------------------------------------MSGDRPKRPLSAYMLWLNET-REQIKKDNPGSKVTDIAKRGGELWRGLK--DKTEWEQKAIKMKEEYNKAVKEYEANGG-----TDSGAPKKRKKAAAKPAKKAKKKESSEEEEEDESE----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05783-1", "uniprot_id": "HMGD_DROME", "id": "Q05783-1", "name": "High mobility group protein D", "aln": "------------------------------------------------------------------------------------------MS-DKPKRPLSAYMLWLNSA-RESIKRENPGIKVTEVAKRGGELWRAMK--DKSEWEAKAAKAKDDYDRAVKEFEANGGS--SAANGGGAKKRAKPAKKVAKKSKKEES-DEDDDDESE----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCZ5-1", "uniprot_id": "Q9VCZ5_DROME", "id": "Q9VCZ5-1", "name": "", "aln": "----------------------------------------------------------------------------------------MSDCGARPKKPMSAFMLWMNSTGRKHIKAEHPDFSVQEVSVKGGEMWRAMADEDKIVWQESATTAMAEYKEKLKQWNFPKEHRFSDTQCICS-------SNTNQCPTLFVYDTMDDSMTPICRKCLSKTRCLH----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E1JIT5-1", "uniprot_id": "E1JIT5_DROME", "id": "E1JIT5-1", "name": "", "aln": "---------------------------------------------------------------------------------------MMSDYGARPKKPMSAFMLWMNSTGRKNIRAEHPDFSVQEVSVKGGEMWRAMADEHKIVWQESASKAMAEYKEKLEKWNAFKEHQTESFPHIYEAPLSSRFSKTNQRPTLFVYDSKDEAMAPICRTCFSKAKCFH----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::. *.::.: . :: :*. .. : *. * * . * : ", "identical_positions": 7, "similar_positions": 19, "identity": "2.62%" }, { "cls_id": "homologset.agr.SGD:S000006258", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61532-1", "uniprot_id": "MK06_MOUSE", "id": "Q61532-1", "name": "Mitogen-activated protein kinase 6", "aln": "-------------------------------------------------------------------------MAEKFESLMNIHG------------------FDLGSR--------------------------------------YMDLKPLGCGGNGLVFSAVDN--DCDKRVAIKKIVLTDPQS--VKHALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQG-PLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLAR-----IMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILDSIPVVHEEDRQELLSVIP-VYIRNDMTEPHR--PLTQLLPGISREALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPTDEPISSHPFHIEDEVDDILLMDETHSH--IYNWE----RYHDCQFSEHDWPIHNNF------------DIDEVQLDPRALSDVTDEEEVQVDPRKYLDGD-REKYLEDPAFDTSYSAEPCWQYPDHHENKYCDLECSHTCNYKTRSSPYLDNLVWRESEVNHYYEPKLIIDLSNWKEQ-SKEKSDKRGKSKCERNGLVKAQIALEEASQQLA--ERERGQ--------GFDFDSFIAGTIQLSAQHQSADVVDKLNDLNSSVSQLELKS---LISKSVSREKQEKGRANLAQLGALYQSSWDSQFVSGGEECFLISQFCCEVRKDEHAEKENT--YTSYLDKFFSRKEDSEMLETEPVEEGKRGERGREAGLLSGGGEFLLSKQLESIGTPQFHSPVGSPLKSIQATLTPSAMKSSPQIPHKTYSSILKHLN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27704-1", "uniprot_id": "MK06_RAT", "id": "P27704-1", "name": "Mitogen-activated protein kinase 6", "aln": "-------------------------------------------------------------------------MAEKFESLMNIHG------------------FDLGSR--------------------------------------YMDLKPLGCGGNGLVFSAVDN--DCDKRVAIKKIVLTDPQS--VKHALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQG-PLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLAR-----IMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPVVHEEDRQELLSVIP-VYIRNDMTEPHK--PLTQLLPGISREALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPTDEPISSHPFHIEDEVDDILLMDETHSH--IYNWE----RYHDCQFSEHDWPIHNNF------------DIDEVQLDPRALSDVTDEEEVQVDPRKYLDGD-REKYLEDPAFDTSYSAEPCWQYPDHHENKYCDLECSHTCNYKTRSPSYLDNLVWRESEVNHYYEPKLIIDLSNWKEQ-SKDKSDKRGKSKCERNGLVKAQIALEEASQQLA--ERERGQ--------GFDFDAFIAGTVQLSAQRESADVVDKLNDLNSSVSQLEMKS---LISKSVSREKQEKGRANLAQLGALYQPSWESQFVSGGEECFLISQFCCEVRKDEHVEKENT--YTSYLDKFFSRKEDSEMLETEPVEEGKRGERGREAGLLSSGGEFLLSRQLESIGTPQFHSPGGSPLKSIQATLTPSAMKSSPQIPHKTYSNILKHLN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16659-1", "uniprot_id": "MK06_HUMAN", "id": "Q16659-1", "name": "Mitogen-activated protein kinase 6", "aln": "-------------------------------------------------------------------------MAEKFESLMNIHG------------------FDLGSR--------------------------------------YMDLKPLGCGGNGLVFSAVDN--DCDKRVAIKKIVLTDPQS--VKHALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQG-PLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLAR-----IMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPVVHEEDRQELLSVIP-VYIRNDMTEPHK--PLTQLLPGISREALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPMDEPISSHPFHIEDEVDDILLMDETHSH--IYNWE----RYHDCQFSEHDWPVHNNF------------DIDEVQLDPRALSDVTDEEEVQVDPRKYLDGD-REKYLEDPAFDTNYSTEPCWQYSDHHENKYCDLECSHTCNYKTRSSSYLDNLVWRESEVNHYYEPKLIIDLSNWKEQ-SKEKSDKKGKSKCERNGLVKAQIALEEASQQLAGKEREKNQ--------GFDFDSFIAGTIQLSSQHEPTDVVDKLNDLNSSVSQLELKS---LISKSVSQEKQEKGMANLAQLEALYQSSWDSQFVSGGEDCFFINQFC-EVRKDEQVEKENT--YTSYLDKFFSRKEDTEMLETEPVEDGKLGERGHEEGFLNNSGEFLFNKQLESIGIPQFHSPVGSPLKSIQATLTPSAMKSSPQIPHQTYSSILKHLN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA57WKX4-1", "uniprot_id": "A0AA57WKX4_DANRE", "id": "A0AA57WKX4-1", "name": "Mitogen-activated protein kinase 6", "aln": "-------------------------------------------------------------------------MAEKFESLMNIHG------------------FDLGPR--------------------------------------YMDLKPLGYGGNGLVFSAVDT--DCDKRVAVKKIVLTDPQS--VKHALREIKIIRRLDHDNIVKVFETLGPSGRRLTEDVSSLTEVNSVYIVQEYMETDLCKVLEQG-LLSEDHARLFMYQLLRGLKYIHSANVLHRDLKPANLFVNTEDLVLKIGDFGLAR-----IMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPVVHEEDRLELQSVIP-VFIKNDMSEPHT--PLAKLLPGVSPEALDFLEKILTFNPMDRLTAEEALAHPYMSDYSFPLDEPVSLHPFHIEDEVDDILLMDESHSQ--VYNWD----RYHESQFSDQDWHLHSTH------------ELEDVQRDPRALSDVTDEEEVQIDPRKYMDGD-CEKFLEDPSFD--LPPEHLWQLEDHHENKYCDQECSYTCNYKAVSPSYLDNLIWRDSEVNHYYEPKLIIDLSNWKEQQSKEKIDKKGKSKCEKNGLVKAQIALKEASQNHTVPEKDRDQEKHQNHNQGFDFDSFIASTIKLSLQPESGD-VDLLNELNTSVSQLDTRAPCGSMSKSISQEKEEKCLVNLAQLGVRAPCPWESFTDCGVAESSLIDQACWDVRKDEQLQKENSSCQSSYLDRLFSKRDDVEPEILEPVEVVS----TTESDFISCSGEIVFNMQLESLAIPGFEGAADIPLKSIQATLAPSAVKHSPQIAHKTYSSIFKHLN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6P5G0-1", "uniprot_id": "MK04_MOUSE", "id": "Q6P5G0-1", "name": "Mitogen-activated protein kinase 4", "aln": "-------------------------------------------------------------------------MAEKGDCIASVYG------------------YDLGGR--------------------------------------FIDFQPLGFGVNGLVLSATDS--RACRKVAVKKIVLSDARS--MKHALREIKIIRRLDHDNIVKVYEVLGPKGSDLQG---ELFKFSVAYIVQEYMETDLACLLEQG-TLTEDHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLAR-----IVDQHYSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGKMLFAGAHELEQMQLILDTIPVVREEDKEELLRVMP-SFVS-STWEVKR--PLRKLLPDVNSEAIDFLEKILTFNPMDRLTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAASQSQ--LSNWD----RYPVSLSSDLEWR-PDRC-----------QDASEVQRDPRAGS-TPLAEDVQVDPRKDSQSS-SERFLEQSHSS-----------MERAF----EADYGRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDLSHWKQA-ASAPPRAAVAADPVSREDEPASLFLEIAQWVKS-----------------------TQSGSERASPPPD-------------------------------------APEPRLSASP---PGHPTPIDGGAS-------------------------PQFDLDVFISR----------------------ALKLCTKP------EDLPENKLGDLNGACISEHPG-------DLVQTEAFSKERW---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31152-1", "uniprot_id": "MK04_HUMAN", "id": "P31152-1", "name": "Mitogen-activated protein kinase 4", "aln": "-------------------------------------------------------------------------MAEKGDCIASVYG------------------YDLGGR--------------------------------------FVDFQPLGFGVNGLVLSAVDS--RACRKVAVKKIALSDARS--MKHALREIKIIRRLDHDNIVKVYEVLGPKGTDLQG---ELFKFSVAYIVQEYMETDLARLLEQG-TLAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLAR-----IVDQHYSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQLILETIPVIREEDKDELLRVMP-SFVS-STWEVKR--PLRKLLPEVNSEAIDFLEKILTFNPMDRLTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQ--LSNWDTCSSRYPVSLSSDLEWR-PDRC-----------QDASEVQRDPRAGS-APLAEDVQVDPRKDSHSS-SERFLEQSHSS-----------MERAF----EADYGRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDLSHWKQA-AGAPPTATGLADTGAREDEPASLFLEIAQWVKS-----------------------TQGGPEHASPPAD-------------------------------------DPERRLSASP---PGRPAPVDGGAS-------------------------PQFDLDVFISR----------------------ALKLCTKP------EDLPDNKLGDLNGACIPEHPG-------DLVQTEAFSKERW---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0V360-1", "uniprot_id": "B0V360_DANRE", "id": "B0V360-1", "name": "Mitogen-activated protein kinase 4", "aln": "-------------------------------------------------------------------------MAWHN-TSPFRYG------------------FDLGAQ--------------------------------------YQDLRPLGTGASGLVLSALDR--RSGLRVAVKKLVMRDAVS--VKHALREVKITRRLQHENVVRVYDVLGSSGHPLPR---DLTHVAAIYIVQECMETDLARLLEQG-PLPAEHATLLFYQLLRGLKFIHSANVLHRDLKPANIFINTEQMLLKIGDFGLAR-----IVDPHYSHKGYLSEGMVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQLILDTVPVIREEDRQELLRVMP-SLVG-HGWQIRR--SFRDLMPEVEDKAIDFLESILTFNPMDRLTAEAALCQPFLQRYSCPQDEPVSLQPFRIEDELEDSLVTESTHTHGLRSHWD----RYDSSLSSDVYWPTQDQCGCMQSVSELGEAEDEEVQRDPRASS-ASHIEEAQVDPRKYSHSSSAERFLEQSHPS-----------LERICGHFSELDCGRSCDYKVGSPSYLDKIAWREGKPQHYSEPKLILDLSNWRNN-SMAAPRQNSAEKLLT---EPGDLFQEISRWVES-----------------------TQSGLHSPGSPQEPPSSPCSPPLPLSPTLMPQSQIQIPAPLTLPSPLSRRSPTPFFSAPPSLLPSSPSSPHHGSSNYPSSSIGCENYEEPSQMRPSGE--EHFDLDVFISQ----------------------ALQICSQSEIMESSDDLKSDNISDVCNVSDDHRPSRTQTPTPEMVKAHGCHKEHW---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40417-3", "uniprot_id": "ERKA_DROME", "id": "P40417-3", "name": "Mitogen-activated protein kinase ERK-A", "aln": "-------------------------------------------------------------------------MEEFNSSGSVVNGTGSTEVPQSNAEVIRGQIFEVGPR--------------------------------------YIKLAYIGEGAYGMVVSADDT--LTNQRVAIKKISPFEHQTY-CQRTLREITILTRFKHENIIDIRDILRVD---------SIDQMRDVYIVQCLMETDLYKLLKTQ-RLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLN-KTCDLKICDFGLAR-----IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDLECIINEKARNYLESLPFKPNV--PWAKLFPNADALALDLLGKMLTFNPHKRIPVEEALAHPYLEQYYDPGDEPVAEVPFRINMENDD-------------------------------------------------------ISRD------------------------------------------------------------------ALKSLIFEETLKFKERQPDNAP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O54949-1", "uniprot_id": "NLK_MOUSE", "id": "O54949-1", "name": "Serine/threonine-protein kinase NLK", "aln": "MSLCGTRANAKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPPHLHHHHHPQHHLHPGSAAAVHPVQQHTSSAAAAAAAAAAAAAMLNPGQQQ-----------PYFPSPAPGQAPGPAAAAPAQVQAAAAATVKAHHHQHSHHPQQQLDIEPDRPIGYGAFGVVWSVTDP--RDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPP---------HIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVN-SNCVLKICDFGLAR-------VEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMRTACEGAKAHILRGPHKQPSLPVLYT-LSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDEGRLRYHTCMCKCCFSTSTGRVYTSDFEPVTNP---------------------------------------------------------------------------------------------------------------------KFDDTFEKNLSSVRQVKEIIHQFILEQQKGNRVPLCINPQSAAFKSFISSTVAQPSEMPPSPLVWE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZSZ3-1", "uniprot_id": "NLK_RAT", "id": "D3ZSZ3-1", "name": "Serine/threonine-protein kinase NLK", "aln": "MSLCGTRANAKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPPHLHHHHHPQHHLHPGSAAAVHPVQQHTSSAAAAAAAAAAAAAMLNPGQQQ-----------PYFPSPAPGQAPGPAAAAPAQVQAAAAATVKAHHHQHSHHPQQQLDIEPDRPIGYGAFGVVWSVTDP--RDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPP---------HIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVN-SNCVLKICDFGLAR-------VEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMRTACEGAKAHILRGPHKQPSLPVLYT-LSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDEGRLRYHTCMCKCCFSTSTGRVYTSDFEPVTNP---------------------------------------------------------------------------------------------------------------------KFDDTFEKNLSSVRQVKEIIHQFILEQQKGNRVPLCINPQSAAFKSFISSTVAQPSEMPPSPLVWE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBE8-1", "uniprot_id": "NLK_HUMAN", "id": "Q9UBE8-1", "name": "Serine/threonine-protein kinase NLK", "aln": "MSLCGARANAKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPPHLHHHHHPQHHLHPGSAAAVHPVQQHTSSAAAAAAAAAAAAAMLNPGQQQ-----------PYFPSPAPGQAPGPAAAAPAQVQAAAAATVKAHHHQHSHHPQQQLDIEPDRPIGYGAFGVVWSVTDP--RDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPP---------HIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVN-SNCVLKICDFGLAR-------VEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMRTACEGAKAHILRGPHKQPSLPVLYT-LSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDEGRLRYHTCMCKCCFSTSTGRVYTSDFEPVTNP---------------------------------------------------------------------------------------------------------------------KFDDTFEKNLSSVRQVKEIIHQFILEQQKGNRVPLCINPQSAAFKSFISSTVAQPSEMPPSPLVWE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AJX5-1", "uniprot_id": "A0A8I6AJX5_RAT", "id": "A0A8I6AJX5-1", "name": "Mitogen-activated protein kinase", "aln": "MSLCGTRANAKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPPHLHHHH-PQHHLHPGSAAAVHPVQQHTSSAAAAAAAAAAAAAMLNPGQQQ-----------PYFPSPAPGQAPGLAAAAPAQVQAAAAATVKAHHHQHSHHPQQQLDIEPDRPIGYGAFGVVWSVTDP--RDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFIHDNVLSALDILQPP---------HIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVN-SNCVLKICDFGLAR-------VEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQ----------------------------------QPSLPVLYT-LSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDEGRLRYHTCMCKCCFSTSTGRVYTSDFEPVTNP---------------------------------------------------------------------------------------------------------------------KFDDTFEKNLSSVRQVKEIIHQFILEQQKGNRVPLCINPQSAAFKSFISSTVAQPSEMPPSPLVWE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41808-1", "uniprot_id": "SMK1_YEAST", "id": "P41808-1", "name": "Sporulation-specific mitogen-activated protein kinase SMK1", "aln": "-------------------------------------------------------------------MNCTLTDNTRAINVASNLGAPQQR-----------TIFAKERISIPG---------------------------------YYEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIVNLIDLEIV---------TSSPYDGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCT-LNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDILIKFGTIKAWNLGKNSNNPVYKKIPWSNIFPFASHEAINLIESLLHWDSTHRLNVEQAISHPFLNEVRK-------------------PDDEPVCLQG---------------------------------------------------------------------------------------------------------------------PFDFTYESELNSMSKLRDYLVEEVKN-----------------FKTDLSSSSL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :* * * * *. ::*:**: ::.:**:.: : .: : * * :: ** :: * * ::**:* ***::***.::***:**.*:: . *** ****** . .::: :.*::**:*.:::. . *::::*:*:.***:**: : :* . :. : . *:.:: :* :.. .*: .: .: :*::. :. : . ", "identical_positions": 57, "similar_positions": 90, "identity": "6.35%" }, { "cls_id": "homologset.agr.SGD:S000006259", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62824-1", "uniprot_id": "EXOC4_RAT", "id": "Q62824-1", "name": "Exocyst complex component 4", "aln": "--MAAEAAGGKYRSTVSKSKDPS--GLLISVIRTLS---------------------------TSDDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEG-PLLQVEGLSDLRLELHSKKMNLHLVLIEELHRHLYIKSTSRVVQRNKEKGKMSSHGKDASPGPLID----VSNISTPRKFLDATQYSAAGSSSVREMNLQDIKEDLDCD----------PEENSTLFMGILIQGLARLKKIPETVKAIKERLEQELKQIVKRSTTQVA---------DSAYQRGESLTVDNQPRLLLELLELLFDKFNAVASAHSIVLGYLQDSVGTQPTQQEEIKLYDMADVWVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYASTGREFAAFFAKKKPQRPKNSLFKFESSSHAIS--MSAYLREQRR---------ELYSRSGELQGGPDDNLIEG----GGTKFVCKPGARNITVIFHPLLRFIQEIEHALGLGPAK-QCLLREFLTIYIKNIFLNQ-VLTEINKEIEGVTKTSDPLKILANADTMKVLGVQRPLLQSTIIVEKTVQDLMNLMHDLSAYSDQFLNMVCVKLQEYKDTCSTAYRGIVQ---SEEKLVISASWAKDDDISRLLKSLPNWTNMAQPKQ------------LRPKREEEEDFIRAAFGKESEVLIGNLGDKLIPPQD----ILRDVSDLKALANMHESLEWLAGRTKSAFSSLSASQMLSPAQESHVNMDLPP------VSEQIMQTLSELAKSFQDMADRCLLVLHLEVRVHCFHYLIPLAKEGNYAIVAN-VESMDYDPLVVKLNKDISAMEEAMSASLQQHKFQYIFEGLGHLISCILINGAQYFRRISESGIKKMCRNIFVLQQNLTNITMS-READLDFARQYYEMLYNTADELLNLVVDQGVKYT---ELEYIHALTLLHRSQTGVGDQTTQNTR-------------LQRLKEIICEQAAIKQATKDKKITTV----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35382-1", "uniprot_id": "EXOC4_MOUSE", "id": "O35382-1", "name": "Exocyst complex component 4", "aln": "--MAAEAAGGKYRSTVSKSKDPS--GLLISVIRTLS---------------------------TSDDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEG-PLLQVEGLSDLRLELHSKKMNLHLVLIEELHRHLYIKSTSRVVQRNKEKGKMSSHGKDPSPGPLID----VSNIPTPRKFLDASQYSAAGGSSVREMNLQDVKEDLECD----------PEENSTLFMGILIQGLARLKKIPETVKAIKERLEQELKQIVKRSTTQVA---------DSAYQRGESLTVDNQPRLLLELLELLFDKFNAVATAHSVVLGYLQDSVGTQLTQQEEIKLYDMADVWVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYASTGREFAAFFAKKKPQRPKNSLFKFESSSHAIS--MSAYLREQRR---------ELYSRSGELQGGPDDNLIEG----GGTKFVCKPGARNITVIFHPLLRFIQEIEHALGLGPAK-QCPLREFLTVYIKSIFLNQ-VLAEINKEIEGVTKTSDPLKILANADTMKVLGVQRPLLQSTIIVEKTVQDLMNLMHDLSAYSDQFLNMVCVKLQEYKDTCSTAYRGIVQ---SEEKLVISASWAKDDDISRLLKSLPNWTNMAQPKQ------------LRPKREEEEDFIRAAFGKESEVLIGNLGDKLIPPQD----ILRDVSDLKALANMHESLEWLAGRTKSAFSNLSTSQMLSPAQESHVNMDLPP------VSEQIMQTLSELAKTFQDMADRCLLVLHLEVRVHCFHYLIPLAKEGNYAIVAN-VESMDYDPLVVKLNKDISAMEEAMSASLQQHKFQYIFEGLGHLISCILINGAQYFRRISESGIKKMCRNIFVLQQNLTNITMS-READLDFARQYYEMLYNTADELLNLVVDQGVKYT---ELEYIHALTLLHRSQTGVGDQTTQNTR-------------LQRLKEIICEQAAIKQATKDKKITTV----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96A65-1", "uniprot_id": "EXOC4_HUMAN", "id": "Q96A65-1", "name": "Exocyst complex component 4", "aln": "--MAAEAAGGKYRSTVSKSKDPS--GLLISVIRTLS---------------------------TSDDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEG-PLLQVEGLSDLRLELHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDAS-VPLID----VTNLPTPRKFLDTSHYSTAGSSSVREINLQDIKEDLELD----------PEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKRSTTQVA---------DSGYQRGENVTVENQPRLLLELLELLFDKFNAVAAAHSVVLGYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYASTGREFAAFFAKKKPQRPKNSLFKFESSSHAIS--MSAYLREQRR---------ELYSRSGELQGGPDDNLIEG----GGTKFVCKPGARNITVIFHPLLRFIQEIEHALGLGPAK-QCPLREFLTVYIKNIFLNQ-VLAEINKEIEGVTKTSDPLKILANADTMKVLGVQRPLLQSTIIVEKTVQDLLNLMHDLSAYSDQFLNMVCVKLQEYKDTCTAAYRGIVQ---SEEKLVISASWAKDDDISRLLKSLPNWMNMAQPKQ------------LRPKREEEEDFIRAAFGKESEVLIGNLGDKLIPPQD----ILRDVSDLKALANMHESLEWLASRTKSAFSNLSTSQMLSPAQDSHTNTDLPP------VSEQIMQTLSELAKSFQDMADRCLLVLHLEVRVHCFHYLIPLAKEGNYAIVAN-VESMDYDPLVVKLNKDISAIEEAMSASLQQHKFQYIFEGLGHLISCILINGAQYFRRISESGIKKMCRNIFVLQQNLTNITMS-READLDFARQYYEMLYNTADELLNLVVDQGVKYT---ELEYIHALTLLHRSQTGVGELTTQNTR-------------LQRLKEIICEQAAIKQATKDKKITTV----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VNH6-1", "uniprot_id": "EXOC4_DROME", "id": "Q9VNH6-1", "name": "Exocyst complex component 4", "aln": "--MDAPPPTKPPRGVKYGKDESAGCGFLVNVIKSLG---------------------------FSETTEERQKEKQKIEAEFKRSDLRLNELVSRHDQQLTQVLPLFSQVSSEVTASRERIHAVKENLGVCKRLLQCRRDELRKMWMDAVQHKYVLEMLEQIQELRKVPQRVVGYTAKRQYLHASKALTDALTTLNG-PLQAVEGLSDLRTDLQTRRQQLYQRLHEELVTQVYTNSANEALSSFQR---TNSSRLNSSFTRGIG----ARRSTDRIEANARVRKALAEMAQSFDLDKAEVIEDADLIY---------PELSMSYFVAIIVESFGMLHKVPDSLETLRVQIQTELLNVVRHTTHQLS---------VSG------ATADTNP--LLSLLEVIFKQFKAIAKTHSLLLKNYLSVG--QKYSVVGPQPYDLTDFWAQAQSVLQLLLTDYLDIQN--AAADESAQTGFSEPTSNINSYFLRRKVPSTKRSMFKFDKSSHVGTSNNSDAFKEHRRNASDASVDDNLAGQLGGSGKGSTSGLFPHEKKQREKILICTPDQSIITKVYLPLMGYIKEIENFMKCKPGQ-PCSLHDFLDNYIKDTFLTKGHNRNLQLTIESLSKNQDAWRTIISPEEIKALNLSRPLLQSTVMVERRLMETKNLIQDLPCYSEDLLKMVCALLKAYREICQAAYRGIVQP-DSEDKRIYSVAWLKDEDISRFLKTLPNWTDLKTYSQKSRHNRKLHRGSFEPSEEESPLQVQQRNIREAEMLTSNLGEGGITQQE----ILVEISVLKELAILQESMEWFSCRVSEFANDLRRPLVNGLNAVPAECGADIA------VKDGTIKVMTNLALEFDELANTCLLVLHLEVRVQCFHYLRSKSSVRTNSYVGSKDDILEPDRQVQVLTKRLSEMDEAFSATLHPRKTRYIFEGLAHLASRILIQASNYLEHIDQITVQRMCRNAIALQQTLSNITAS-REVALDQARHFYELLCMEPDEILNALLERGTQFS---EMQLLNALQLSCKSFG-ITDANLLASY-------------QQKLSDILGAKPSKGVVV------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32855-1", "uniprot_id": "SEC8_YEAST", "id": "P32855-1", "name": "Exocyst complex component SEC8", "aln": "MDYLKPAQKGRRRGLSINSLSETQQSAMNSSLDHLQNDLNRINLQWNRILSDNTNPLELALAFLDDTSVGLGHRYEEFNQLKSQIGSHLQDVVNEHSQVFNTNVASYGKAVSSIMQAQEQTLNLKNCLKEANEKITTDKGSLQELNDNNLKYTKMIDVLVNIEELLQIPEKIEENIRKENFHQVQILLERGFILMNNKSLKTVEILKPINQQLELQEHLLFNNLIEEIHDIMYSKSNKTNFTRVTNNDIFKIISISHNGFTSLENYLYNIVNIDIMEHSKTINKNLEQFIHDQSLNKGNIMLQENAATQAPLAPSRNQENEGFNRIGFLLKTINNINKLPVAFNIITERAKEEIHNIIVKSTESIRSKHPSLLKMATSLKNDNHFGLPVQDILSIILRECFWEIFLKLLYAIQCHRAIFEMSNILQPTSSAKP-AFKFNKIWGKLLDEIELLLVRYINDPELISSNNGSIKP--INGATNNAPTLPKRKNPKIFSLEYNIEDNSSVKD--QAFELKALLK---------DIFPGFSVSSNMDLDSIYVKDESFEQDEPLVPPSVFNMKVILDPFLLFTQSTSTIVPSVLTQNTISSLTFFDDYMNKSFLPK-IQMTMDYLFTVEVESNNPYALELSDE-------NHNIFKTALDFQRLFYNLLNVFNTANTFREKISYCILDLLNHFYNYYLGLFNSLIGTSDRHLTRKIITAWLQNGILMDQEQKILNGDETLFHEES-----------IELFKEIPHFYQAGKGLSKSDLFNNLTLDTILQFSASVLWILNWLPGLKKAINIDEVSQEPMLDADRLRSSWTFSESMDLNYSNPSSSPNSLGNLKILLDDKASKKFDETIDGFKTLKFKLITILRFNIRALCIYDIG--SFFQNTKIWNMDVGSIELDQNIASLISELRRTESKLKQQLPEKEKNSIFIGLDIVNNYALIKGAKSIKVLNHNGIKKMLRNVNVLQHAYRNLSSEPSKINMNVTMNFYSLCGSSEAELFEYIKDNELPHCSVEDLKTILRLQFSEEMHRQLKRQSTSSTKGSIKPSNKRYTEALEKLSNLEKEQSKEGARTKIGKLKSKLNAVHTANEK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *. . . : . : . : * .: :. .:: .: . *:::: .* :. : : . . : :::: :*: * .: : :..*::: : :::. ::::* :*::: ::*::: ..:: . * .. ::. .* ** *. :. :*. :. *. * :*: :* :* . . . . . . : : . .:: :: : : * . :.:::: : ::*:* :.: : : : *: ::: ::* .: :. : : * * ::. * : : . . :.: ..* : . :::**. *:: : :: : * : . : . : ::* ::::..* . : :: : :: . ..: : *. :. : *:: : :. . : : *: *::. ** : :: : :..:. . : .: :::::: .:: . : *::: : :.: : *: : : :..:: . . .:* :: : :.: * : .: :. .* ::::: . : : . ** :. ** :.* : .. .. . . :.: : : : *. : : :*::::*. *:: : : . :: * : * . : :. :. * :: . ** ** : . **:.:: :. :.. :::* ** .**: *:: . : :: : ::*.: *::: : :. . ::: : * : . : . : ::*.:: :. . ", "identical_positions": 75, "similar_positions": 356, "identity": "6.82%" }, { "cls_id": "homologset.agr.SGD:S000006260", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q561R7-1", "uniprot_id": "TF2H3_RAT", "id": "Q561R7-1", "name": "General transcription factor IIH subunit 3", "aln": "--------MAADEDE-------LNLLVIIVDTNPIWWGKQALKESQF-TLSKCMDAVMVLANAHLFMNRSNQLAVIASHIQESRFLYPGKNGRLGDFFGDPGNALPDCNPSGSKDGKYELLTAANEVIAEEIKDLMTKS--DIKGQHTETLLAGSLAKALCYIHRASKAVKDNQEMKSRILVIKA----AEDSALQYMNFMNVIFAAQKQNILIDACVLD--SDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQLILPPPIHVDYRAACFCHRSLIEIGYVCSVCLSIFCNFSP--ICTTCETAFKISLPPVLKAK------KKKQKVSL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VD76-1", "uniprot_id": "TF2H3_MOUSE", "id": "Q8VD76-1", "name": "General transcription factor IIH subunit 3", "aln": "--------MAADEDE-------LNLLVIIVDTNPIWWGKQALKESQF-TLSKCMDAVMVLANSHLFMNRSNQLAVIASHIQESRLLYPGKNGGLGDFFGDPGNALPDCNPSGSKDGKYELLTVANEVIAEEIKDLMTKS--DIKGQHTETLLAGSLAKALCYIHRVNKAVKDNQEMKSRILVIKA----AEDSALQYMNFMNVIFAAQKQNILIDACVLD--SDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQLILPPPIHVDYRAACFCHRSLIEIGYVCSVCLSIFCNFSP--ICTTCETAFKISLPPVLKAK------KKKQKVSL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13889-1", "uniprot_id": "TF2H3_HUMAN", "id": "Q13889-1", "name": "General transcription factor IIH subunit 3", "aln": "--------MVSDEDE-------LNLLVIVVDANPIWWGKQALKESQF-TLSKCIDAVMVLGNSHLFMNRSNKLAVIASHIQESRFLYPGKNGRLGDFFGDPGNP-PEFNPSGSKDGKYELLTSANEVIVEEIKDLMTKS--DIKGQHTETLLAGSLAKALCYIHRMNKEVKDNQEMKSRILVIKA----AEDSALQYMNFMNVIFAAQKQNILIDACVLD--SDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQLILPPPVHVDYRAACFCHRNLIEIGYVCSVCLSIFCNFSP--ICTTCETAFKISLPPVLKAK------KKKLKVSA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPX4-1", "uniprot_id": "Q9VPX4_DROME", "id": "Q9VPX4-1", "name": "General transcription factor IIH subunit 3", "aln": "--------MEADQAASKEAESCIDLLVIVLDTNP---SQHFVRQNPQ-NLTQILEAVIAFGNAHLMQKAQNKLAVVSCSHHATNFLYPLPRRQV---------------ELRQVDGQYEAFNLVEKTVKQQLGSILMNA--PRLSAPCESLLAGSMSMALCYISRLQRNLAPGVKMHSRILVVTG----SNECASQYMTFMNVFFTAQKLGITIDTCALD--KTLSLLQQGCDITSGQFLKVTQLDGLLQYLLWVFLPAPQIRHKLVLPPPPKVDYRASCFCHRELIDIGYVCSVCLSVFCKYSP--ICTTCHTIFKNPGPLPIKGK------KKKKTDKQM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12004-1", "uniprot_id": "TFB4_YEAST", "id": "Q12004-1", "name": "General transcription and DNA repair factor IIH subunit TFB4", "aln": "MDAISDPTFKHARSRKQVTEESPSLLTVIIEIAPKLWTTFDEEGNEKGSIIKVLEALIVFLNAHLAFNSANKVAVIAAYSQGIKYLYPESTSALKASESENKTR---SDLKIINSDMYRRFRNVDETLVEEIYKLFELEKKQIEQNSQRSTLAGAMSAGLTYVNRISKESVTTS-LKSRLLVLTCGSGSSKDEIFQYIPIMNCIFSATKMKCPIDVVKIGGSKESTFLQQTTDATNGVYLHVESTEGLIQYLATAMFIDPSLRPIIVKPNHGSVDFRTSCYLTGRVVAVGFICSVCLCVLSIIPPGNKCPACDSQFDEHVIAKLKRKPVVPRLKAKKKVTKP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .**.:::: * . . .: : ::*::.: *:** : *::**::. : . *** : .. *. : .::.: ::: .:: .: ***::: .* *: * .: ::**:**:. ::: **: :** :*:* * **. :. . :*** * *.* :*:* . .*:*** .:: . * :: * **:*::*: :: :*::*****.::. .* *.:*.: *. :* * * * . . ", "identical_positions": 65, "similar_positions": 104, "identity": "19.01%" }, { "cls_id": "homologset.agr.SGD:S000006262", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BW66-1", "uniprot_id": "S2548_MOUSE", "id": "Q8BW66-1", "name": "Solute carrier family 25 member 48", "aln": "--------------------------------------------------------------------------MGSFQLEDFVAGWIGGVASVIVGYPLDTVKTRLQAGVG----YANTFNCIRMVYKRERVFGFFKGMSFPLASIAIYNSVVFGVFSNTQRFLSKYRCGELEAGPGRSLSDLLLASMLTGVVSVGLGGPVELIKIRLQMQTQPFREASHGLKS-----------RAVA-----AYQGPVHCIATIVQMEGLTGLYRGASAMLLRDIPGYCFYFIPYVFLSEWIT----PEACTGPSPYAAWLAGGIAGAISWGTATPMDVVKSRIQADGVYL-NKYRGVVDCISQSYQQEGFKVFFRGITVNAVRGFPMSAAMFLGYELSLKALRGEHTVRSE---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A961-1", "uniprot_id": "D4A961_RAT", "id": "D4A961-1", "name": "Solute carrier family 25 member 48", "aln": "--------------------------------------------------------------------------MGSFQLEDFAAGWIGGVASVIVGYPLDTVKTRLQAGVG----YANTFNCIRMVYKRESVFGFFKGMSFPLASVAIYNSVVFGVFSNTQRFLSQYRCRELEDCPGRSLSDLLLASMVTGMVSVGLGGPVDLIKIRLQMQTQPFQEASHGLKS-----------RAVA-----AYQGPVHCFATIVRTEGLTGLYRGASAMLLRDIPGYCFYFIPYVFLSDWIT----PEACTGPSPYGVWLAGGIAGAISWGTATPMDVVKSRIQADGVYL-NKYRGVLDCISQSYQQEGFKVFFRGITVNAVRGFPMSAAMFLGYELSLKALRGDHTVRNK---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZT89-1", "uniprot_id": "S2548_HUMAN", "id": "Q6ZT89-1", "name": "Solute carrier family 25 member 48", "aln": "--------------------------------------------------------------------------MGSFQLEDFAAGWIGGAASVIVGHPLDTVKTRLQAGVG----YGNTLSCIRVVYRRESMFGFFKGMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLGGPVDLIKIRLQMQTQPFRDANLGLKS-----------RAVAPAEQPAYQGPVHCITTIVRNEGLAGLYRGASAMLLRDVPGYCLYFIPYVFLSEWIT----PEACTGPSPCAVWLAGGMAGAISWGTATPMDVVKSRLQADGVYL-NKYKGVLDCISQSYQKEGLKVFFRGITVNAVRGFPMSAAMFLGYELSLQAIRGDHAVTSP---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DHS9-1", "uniprot_id": "S2548_DANRE", "id": "Q6DHS9-1", "name": "Solute carrier family 25 member 48", "aln": "--------------------------------------------------------------------------MTVFQLDDFLAGWIGGASSVIVGHPLDTVKTRLQAGKG----YKNTFHCVVTIYKKENVIGFFKGLSFPLASITLYNSMVFGFFSNTQRLISKYRYGD--GRHPCSMLDLTVASMLTGLVSVGVGAPVDLVKIRLQMQTQPVLAENFNLAGNGS-----VPLRSMGIQSQSFYRGPLHCISTVLQNEGIQGLYRGAGAMILRDIPGYALYFIPYTLFCNWLN----PDDNSSPPPCCIWLAGGLAGSISWVTATPSDVVKSRLQADAMHQ-RKYKGILHCIMQSYRTEGIHVFFRGATVNAIRGFPMCATMFLGYELSLQFFRSF---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8CFJ7-1", "uniprot_id": "S2545_MOUSE", "id": "Q8CFJ7-1", "name": "Methylated amino-acid transporter SLC25A45", "aln": "-----------------------------------------------------------------------------MPVEEFVAGWISGAVGLVLGHPFDTVKVRLQTQST----YQGIVDCVVKTYRHESVLGFFKGMSFPIASVALVNSVLFGVYSNTLLALTATSHQERRAQPP-SYTNIFIAGCTGGLLQAYCLAPFDLIKVRLQNQTEPRMQISSSMPR---------------------YRGPVHCAASILREEGPQGLFRGSWALVLRDTPTLGMYFVTYEGLCRQYT----PEG-QNPSSATVLVAGGFAGIASWITATPFDVIKSRMQMDGLKG-RKYGGMLDCMASSFRQEGIGVFFKGMTLNSARAFPVNAATFLSYEYLLRLWR-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZL04-1", "uniprot_id": "D3ZL04_RAT", "id": "D3ZL04-1", "name": "Solute carrier family 25 member 45", "aln": "-----------------------------------------------------------------------------MPVEEFVAGWISGAVGLVLGHPFDTVKVRLQTQNT----YQGIVDCVVKTYRHESVLGFFKGMSFPIASVALVNSVLFGVYSNTLLALTATSHQERRAQPP-SYTNIFIAGCTGGLLQAYCLAPFDLIKVRLQNQTEPRMQIGSSTPR---------------------YRGPVHCAASILKEEGPQGLFRGSWALVLRDTPTLGMYFVTYEGLCRQYT----PEG-QNPSSATVLVAGGFAGIASWITATPFDVIKSRMQMDGLKG-RKYGGMLDCMASSFRQEGIGVFFKGMTLNSARAFPVNAATFLSYEYLLRLWR-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N413-1", "uniprot_id": "S2545_HUMAN", "id": "Q8N413-1", "name": "Methylated amino-acid transporter SLC25A45", "aln": "-----------------------------------------------------------------------------MPVEEFVAGWISGALGLVLGHPFDTVKVRLQTQTT----YRGIVDCMVKIYRHESLLGFFKGMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPP-SYMHIFLAGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPR---------------------YQGPVHCAASIFREEGPRGLFRGAWALTLRDTPTVGIYFITYEGLCRQYT----PEG-QNPSSATVLVAGGFAGIASWVAATPLDMIKSRMQMDGLRR-RVYQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVNAVTFLSYEYLLRWWG-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IS41-1", "uniprot_id": "S2547_MOUSE", "id": "Q6IS41-1", "name": "Solute carrier family 25 member 47", "aln": "--------------------------------------------------------------------------------MDFVAGAIGGVCGVAVGYPLDTVKVRIQTEAK----YAGIWHCIRDTYRQERVWGFYRGLSLPVCTVSLVSSVSFGTYHHCLAHICRFRYGSTDAKP--TKADITLSGCASGLVRVFLTSPTEVAKVRLQTQTQAQTQQRRSSASWTSGAPALCPTPTACLEPRPKYSGPLHCLVTVAREEGLRGLYKGSSALLLREGHSFATYFLSYAMLCEWLT----PAGHSQPDVLGVLVAGGCAGVLAWAVATPMDVIKSRLQAD-GQGQHRYRGLLHCVVTSVREEGPRVLFKGLALNCCRAFPVNMVVFVAYEAVLRLTQSLLT-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6J329-1", "uniprot_id": "S2547_RAT", "id": "Q6J329-1", "name": "Solute carrier family 25 member 47", "aln": "--------------------------------------------------------------------------------MDFVAGAIGGVCGVAVGYPLDTVKVKIQTEAK----YTSIWHCVRDTYRQERLWGFYRGLSLPVCTVSLVSSVSFGTYHHCLAHICRFRYGSTDVKP--TKADITLSGCASGLVRVFLTSPTEVAKVRLQTQAQSQTQQRRPSASWTSVAPALCPAPTACLEPRPKYSGPLHCLVTVAREEGLRGLYKGSSALLLREGHSFATYFLSYAVLSEWLT----PAGQSQPDVLGVLVAGGCAGVLAWAVATPMDVIKSRLQAD-GQGQQRYRGLLHCVVTSVREEGPRVLFKGLALNCCRAFPVNMVVFVAYEAVLRLTQGLLT-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6Q0C1-1", "uniprot_id": "S2547_HUMAN", "id": "Q6Q0C1-1", "name": "Solute carrier family 25 member 47", "aln": "--------------------------------------------------------------------------------MDFVAGAIGGVCGVAVGYPLDTVKVRIQTEPK----YTGIWHCVRDTYHRERVWGFYRGLSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKP--TKADITLSGCASGLVRVFLTSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEP--KYRGPLHCLATVAREEGLCGLYKGSSALVLRDGHSFATYFLSYAVLCEWLS----PAGHSRPDVPGVLVAGGCAGVLAWAVATPMDVIKSRLQAD-GQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAYEAVLRLARGLLT-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1ECW7-1", "uniprot_id": "S247A_DANRE", "id": "Q1ECW7-1", "name": "Solute carrier family 25 member 47-A", "aln": "-----------------------------------------------------------------------------MHFADFLAGSFGGACGVAVGYPLDTVKVRIQTQKQ----FTGIWQCIVLTIRKEGVHGFFKGMFLPITTISMTSSVVFGTYRNCLQALSYIRKAEN------TKLDVFMSGLAGGVAQVSVMSPGDIVKVRLQCQTESRHSVNPKYSVKP------------------KYSGPIHCLLSICREQGLSGLYRGALPLALRDGPSFATYFLTYHTLCARLT----PDGQKEPEWTVVLLSGGVAGMSGWAVGTPMDVIKARLQMDGVRGQRRYRGLLHCLTVTTRTEGLGVFFRSLGINCLRAFPVNMVVFAVYEVSVRVLRSAPLVS-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A4QNX2-1", "uniprot_id": "S247B_DANRE", "id": "A4QNX2-1", "name": "Solute carrier family 25 member 47-B", "aln": "-----------------------------------------------------------------------------MHLADFLAGSVGGAFGVAVGYPLDTVKVRLQTQTG----YSGFWQCVRKTCRNEGLQGFYRGMSMPISTVSISSSLVFGTYRNILQFLHQLQHRSAGEPH--HKAHIFLAGFTGGVTQVLVMAPADIVKVRLQCQTEPVQHISQESSSK--------------------YRGPVQCLLRIARDEGLLGLYKGSAALALRDGPSFATYFLTYNTICEILT----TENQR-PGWPVVLLAGGVSGMCGWAVGTPMDVIKSRLQVDGVSG-RRYRGFLHCITHSVRTEGSGVLFRGLTVNCIRAFPVNMSVFAMYEAVVRLLR-----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BL03-1", "uniprot_id": "S2529_MOUSE", "id": "Q8BL03-1", "name": "Mitochondrial basic amino acids transporter", "aln": "------------------------------------------------------------------------------MALDFLAGCAGGVAGVIVGHPFDIVKVRLQVQSTEKPQYRGTLHCFQSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGQD-----------SPLNQFLAGAAAGAIQCVICCPMELAKTRLQLQAVG-----PARTY----------------------KGSLDCLVQIYRHEGLRGINRGMVSTLLRETPSFGVYFLTYDVMTRAMG----CEPGDRLLVPKLLLAGGTSGITSWLSTYPMDVVKSRLQADGLQGTPRYRGIVDCMRQSYQAEGWQVFTRGLASTLLRAFPVNAATFATVTVVLTYTRGEEAQVDSEAALGTSPTPAGSALAQPSSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5HZE0-1", "uniprot_id": "S2529_RAT", "id": "Q5HZE0-1", "name": "Mitochondrial basic amino acids transporter", "aln": "------------------------------------------------------------------------------MALDFLAGCAGGVAGVIVGHPFDTVKVRLQVQNTEKPQYRGTLHCFQSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGQD-----------SPLNQFLAGAAAGAIQCVICCPMELAKTRLQLQAAG-----PARAY----------------------KGSLDCLVQIYRHEGLRGINRGMVSTLLRETPSFGVYFLTYDVLTRAMG----CEPGDRLLVPKLLLAGGTSGITSWLSTYPMDVVKSRLQADGLQGTPRYRGIVDCMRQSYQAEGWQVFTRGLASTLLRAFPVNAATFATVTVVLTYIRGEEDQVDSEAAPGASTTPAGPALAQPSSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N8R3-1", "uniprot_id": "S2529_HUMAN", "id": "Q8N8R3-1", "name": "Mitochondrial basic amino acids transporter", "aln": "------------------------------------------------------------------------------MALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGHD-----------SPLNQFLAGAAAGAIQCVICCPMELAKTRLQLQDAG-----PARTY----------------------KGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRALG----CEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFATVTVVLTYARGEEAGPEGEAVP---AAPAGPALAQPSSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TAT4-1", "uniprot_id": "A0AB32TAT4_DANRE", "id": "A0AB32TAT4-1", "name": "Mitochondrial basic amino acids transporter", "aln": "MLTGNARKQLMPRLLKKTPRPSVRVVTVRQCRSPRYLLCPRTPSICRRALITSIGVPTAQPDIPATPPDSSTTVHSDTSRHDHISSKLSGAAGVLVGHPFDTVKVRLQVQSVDKPLYRGTFHCFQSIIRQESVLGLYKGIGSPMMGLTFINAIVFGVQGNAMRRLGED-----------TPLNQFLAGAAAGSIQCVICCPMELAKTRMQMQGTGEKKSSSRKVY----------------------KNSLDCLARIYQREGLRGVNRGMVTTLIRETPGFGVYFLAYDLLTRSLG----CEPDDPYMIPKLLFAGGMSGIASWLSTYPVDVIKSRLQADGVGGKYQYSSIMDCTRKSIQREGFRVFTRGLTSTLLRAFPVNAATFATVTLFLLYVRPDEGSKDCEAAH----HATLQQQAQPSSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32331-1", "uniprot_id": "YMC1_YEAST", "id": "P32331-1", "name": "Mitochondrial glycine transporter YMC1", "aln": "------------------------------------------------------MSEEFPSPQLIDDLEEHPQHDNARVVKDLLAGTAGGIAQVLVGQPFDTTKVRLQTSST----PTTAMEVVRKLLANEGPRGFYKGTLTPLIGVGACVSLQFGVNEAMKRFFHHRNADMS---STLSLPQYYACGVTGGIVNSFLASPIEHVRIRLQTQTGSGTN--------------------------AEFKGPLECIKKLRHN---KALLRGLTPTILREGHGCGTYFLVYEALIANQMNKRRGLERKDIPAWKLCIFGALSGTALWLMVYPLDVIKSVMQTDNLQKPKFGNSISSVAKTLYANGGIGAFFKGFGPTMLRAAPANGATFATFELAMRLLG-----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. .* : :* *:* .*.::*. . .* *:::* *: : :: ** : . .. * * : : *:* * ..:.* : .: :* . :*: **: * : . *. :* * * *::*: :* * .. * .: :. . *. * * : ", "identical_positions": 35, "similar_positions": 57, "identity": "8.22%" }, { "cls_id": "homologset.agr.SGD:S000006269", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q04890-1", "uniprot_id": "SOX12_MOUSE", "id": "Q04890-1", "name": "Transcription factor SOX-12", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MVQQRGARAKRDGGPPPPGPGPAAEGAREPGWCKTP--------------------------------------------------------SGHIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAERLRLKHMADYPDYKYRPRKKSKGAPAKARP-------RPPGGGGGGSRLKPGPQLP------------------GRGGRRASGGPLGGGAAAP------------------EDDDEDEEEELLEVRLLETPG----------------------RELWRMVPAGRAARGPAERAQGP-------------SGEG-AAASAAS------------------------------------------------------------------------------------------------------------------------PTLSEDEEPEEEEEEAATAEEGEEE----------TVVSGEEPLGFLSRMPPGPAGLDCSALDRDPDLLPPS---------------------------------------------GTSHFEFPDYCTPEVTEMIAGDWRSSSIADLVFTY-----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15370-1", "uniprot_id": "SOX12_HUMAN", "id": "O15370-1", "name": "Transcription factor SOX-12", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MVQQRGARAKRDGGPPPPGPGPAEEGAREPGWCKTP--------------------------------------------------------SGHIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAERLRLKHMADYPDYKYRPRKKSKGAPAKARP-------RPPGGSGGGSRLKPGPQLP------------------GRGGRRAAGGPLGGGAAAP------------------EDDDEDDDEELLEVRLVETPG----------------------RELWRMVPAGRAARGQAERAQGP-------------SGEGAAAAAAAS------------------------------------------------------------------------------------------------------------------------PTPSEDEEPEEEEEEAAAAEEGEEE----------TVASGEESLGFLSRLPPGPAGLDCSALDRDPDLQPPS---------------------------------------------GTSHFEFPDYCTPEVTEMIAGDWRPSSIADLVFTY-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PCG2-1", "uniprot_id": "M9PCG2_DROME", "id": "M9PCG2-1", "name": "", "aln": "-----------MMERLSTHLSLTGLSLAHPLQTHLGSGGGTHHLGQLAAAVHQQQQQQQQSDQGLGHSHHLHGQQLSLNHQHHHPHQSPQHQQQHQHHPCSSNSSNGSPNGSTG----LGLHPHSALHLAHHHSQLHQHHPAGQQQQHSQPPVSSSSTSHHSQSQALSHQTHSNGSSQLGGGSASGAGSVAGGAANSHHSAPASSSVMAAAAAAHLHHNSQASPISNLHQNMGSLMNSGSSASDVFFSLMIQNTTKRQNEEHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKALRRDGYPY--PMPYPSVPVEALRAGITPGYFAP------------------GPTAAAYHLGSHLGQTSTPTTTQATLSGQMDKFALERSSYLSNSSQASAYSAYLDPSVLTKAYFDSKMYQDRAANYAFDISKIYGAQQHAAAHHQQQQQQQQQ-------------QQQQQQQLLLSGGGGSGGGGSA--------------------------------------------------------------------------------------------------------------SSHNNNSSSGLDDRDATPQLEAVESKPHLHSPSDVGLDYAQYAQQYGGQLAAAAGGAVGGGAAGAAGGSAGG---------------------------------------------GSGGATAADFRRPLTVIFXPPSSNGSEELNLSMT------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q24533-1", "uniprot_id": "DICH_DROME", "id": "Q24533-1", "name": "SOX domain-containing protein dichaete", "aln": "------------MATLSTHPNYG------------------FHLGQAQGLEDYAPQSQLQLSPGMD-----------------------MDIKRVLHYSQSLAAMGGSPNGPAG----QGVNGSSGMG---HH-------------------MSSHMTPHHMHQAVSAQQTLSPNSS-IGSAGSLGSQSSLGSNGSGLNSSSG-------------------------HQSAG----------------MHSLATSPGQEGHIKRPMNAFMVWSRLQRRQIAKDNPKMHNSEISKRLGAEWKLLAESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKNPLTAG-------PQGGLQMQAGGMGQQKLGAGP------------------GAGAGGYNPFHQLPPYFAP-------------------SHHLDQGYPVPYFGGFDP---------------------LALSKLHQSQAAAAAAVNNQGQQQGQ-------------APPQLPPTSLS--------------------------------------------------------------------------------------------------------------------------SFYSGIYSGIS----APSLYAAHS--------------ANAAGLYPSSSTSSPG--------SSPGTITPN---------------------------------------------GMDGSMDSALRRPVPVLY----------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PFG6-1", "uniprot_id": "M9PFG6_DROME", "id": "M9PFG6-1", "name": "", "aln": "-------------------------------------------MTSISALLHRSHSHSNG-----------------------------YTSSGSSNHSHSSSLSPQLPGINLG----LGMVGGLGMGMSVGVG-----------------SGSGNTTPPPMPPADLAVPPAAPTPVAPKMHQHTHHHGNSHHNAPTSHSNSN-------------------------------------------------TGSHHNSHDHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKTLNKSPVP--------GGGGGGGGGGANGGVNAG------------------GAGNSGPSGPGSVGSPKDMQ------------------PQLSPLGQSLPHLHGHPHQS---------------------PYQSHPHHPHPHPHHVQLAAATLS-------------AKYGFGSPLELS------------------------------------------------------------------------------------------------------------------------LPRLPNAFPGLAHYPLDPTLALDLQARLQAMYAGSIYHPWRYLPLISPETPPSPPSSSGTGISSYGCVKSEK---------------------------------------------SSPNAVVASAASPPNIIXPTPLRFGAGTSSSAEHVV----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40657-1", "uniprot_id": "SOX15_DROME", "id": "P40657-1", "name": "Putative transcription factor SOX-15", "aln": "MEPSYDHEHPHHLLTNYNSKKYPHVSRTPEYSHSTGSDYPEHGGYLTDGRLMHESNSDAGIYHVRQGSEHSSPSLHSPAIQSSGYENEHLNEAVLAAHSHSHSPMPMVSSAYVGGGTASGSLINSNIPLLGGGGNSVLNKFLSHPHAGMVGGGTGQMEDCTSHSPIEAASMWSYDYKGDLCAPNCGYLERHKPLPADLKYRPG------------------------------------------------GTQSKSAKESRIRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQDRRPYVEEAERLRVIHMTEHPNYKYRPRRRKQSKLRAMQPGGKEQSESSPNPGTGGSKSNPKLATPPLATASSSYTTPTDESTCNSTNQNHGQSTPGGLYEQPLKPTYSPSSVDCYSNADSTEQIESLAANCPPALLNESSPTGGGYDNSLLLKKLTKPSPSRAAKSRQEKLAKSEEKNKGSQSQGQ-------------SQQGIYAATYPLAPTSVAVVAARGMYVTCNNRGLLDHGHSVKGTFYPPVSVSEDDNSTSMRNSISALQQHCNVVTSTPSSSGGTMPTSEMSSYTVSMADNCGNLRLSMNELSGNEYLPSANAYGMQYEDFLRYQSNDMDYSTSAVEHKETTSDSASGQKCLKYPDTNQNYDDYEAEAYSNAMLPATAASYYTQLPYPPTSLAAFPLQLAVPFQQTTSGAYGAQPIQSGYLHYGNYGGYEGMAQSQPQNQAPVHHQQASHSAPPSLSVPPNQTVTSNSAAISMQQHHHHHFGPAPGMVGVGVGVGVGVGVGEMLFEQQQRKDDEISNILAGVRKTCYSN-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40656-1", "uniprot_id": "SOX14_DROME", "id": "P40656-1", "name": "Putative transcription factor SOX-14", "aln": "-----------MIAKPNQATTEPPLSLRPGTVPTVPATTPARPATITIQRRHPAPKADSTPHTLPPFS--------------------PSPSPASSPSPAPAQTPGAQKTQSQAAITHPAAVASPSAPVAAAAPKTPKTPEPRSTHTHTHTHSQHFSPPPRESEMDGERSPSHSGHEMTLSMDGIDSSLVFGSARVPVNSSTP---------------------------------------------YSDATRTKKHSPGHIKRPMNAFMVWSQMERRKICERTPDLHNAEISKELGRRWQLLSKDDKQPYIIEAEKLRKLHMIEYPNYKYRPQKKQTRSPGSLKPNQDADGCEARNDTTNNNNSLTTLAIN------------------GTTTAGRKSKRSTSTCQSGSASKRLRNDSGDTSSKPKYEVKMESAEQLNSADIILPSADNLISYQSSEYLPLSTLSNADCDEKLHSELSSGPLESRENLSEVVNRFLPLFLGGNEDSQLGVSSLTQSQHNQSDPTAGLMDN-------------------------------------------------------------------------------------ISDISPINDREELTEEVMRYLPYLEVNPSSDGLTLKVESSSLLGKPLNEPVFDSEDNIVNDANLHSASHQIPPYVPDSHDCFAEDCGGDSSSHQVEFEVVRPQTVTMTMTCTLPYGGPDAGHTTFQADDFN--AIPSAAEDSECSILTTSNSPQIGFNGSSFVEADAIGSTCTYAQQDYTGSVIETHNDLNYAAHDNNGALLAYTFEDLPPQPTGSHLEFNTNKYEFASYYKM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25042-1", "uniprot_id": "ROX1_YEAST", "id": "P25042-1", "name": "Repressor ROX1", "aln": "----------------------------------------------------------------------------------------MNPKSSTPKIPRPKNAFILFR-------------------------------------------QHYHRILIDEWTAQGVEIPHNSNISKIIGTKWKGLQPEDKAHWENLAEKEK-------------------------------------------------------LEHERKYPEYKYKPVRKSKKKQLLLKEIEQQQQQQQKEQ-QQQKQSQPQLQQPFNNNIVLMKRAHSLSPSSSVSSSNSYQFQLNNDLKR--------LPIPSVNTSNYMVSRSLS------------------GLPLTHDKTARDLPQLSSQLN------------SIPYYSAPHDPSTRHHYLNVAQAQP---------------------RANSTPQLPFISSIINNSSQTPVTT------------TTTSTTTATSSPG-----------------------------------------------------------------------------------------------------------------------KFSSSPNSSVLENNRLNSINNSNQYLPPPLLPSLQDFQLDQYQQLKQMGPTYIVKPLSHTRNNLLSTTTPTH----------------------------------------------HHIPHIPNQNIPLHQIINSSNTEVTAKTSLVSPK-----------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * : : ::::: . :: : .* . : : *: : :: * . .. .. . : . . . ", "identical_positions": 4, "similar_positions": 31, "identity": "0.47%" }, { "cls_id": "homologset.agr.SGD:S000006270", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C878-1", "uniprot_id": "UBA3_MOUSE", "id": "Q8C878-1", "name": "NEDD8-activating enzyme E1 catalytic subunit", "aln": "MADGEEPEKKRRRIEELLAEKMAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFR-QIHVIDMDTIDVSNLNRQFLFRPKDVGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNY-EDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVN-FPMCTIASMPRLPEHCIEYVRMLQWPKEQPFGDGVPLDGDDPEHIQWIFQKSIERASQYNIR--GVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLN--NYLVFNDVDGLYTYTFEAERKENCPACSQLPQNIQFSP--SAKLQEVLDYLTNSASLQMKSPAITATLE-GKNRTLYLQSVTSIEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFT-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99MI7-1", "uniprot_id": "UBA3_RAT", "id": "Q99MI7-1", "name": "NEDD8-activating enzyme E1 catalytic subunit", "aln": "MADGEEPEKKRRRIEELLAEKMAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFR-QIHVIDMDTIDVSNLNRQFLFRPKDVGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNY-EDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVN-FPMCTIASMPRLPEHCIEYVRMLQWPKEQPFGDGVPLDGDDPEHIQWIFQKSVERASQYNIR--GVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLN--NYLVFNDVDGLYTYTFEAERKENCPACSQLPQNIQFSP--SAKLQEVLDYLTNSASLQMKSPAITATLE-GKNRTLYLQSVTSIEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFT-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TBC4-1", "uniprot_id": "UBA3_HUMAN", "id": "Q8TBC4-1", "name": "NEDD8-activating enzyme E1 catalytic subunit", "aln": "MADGEEPEKKRRRIEELLAEKMAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFR-QIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNY-EDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVN-FPMCTIASMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDGDDPEHIQWIFQKSLERASQYNIR--GVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLN--NYLVFNDVDGLYTYTFEAERKENCPACSQLPQNIQFSP--SAKLQEVLDYLTNSASLQMKSPAITATLE-GKNRTLYLQSVTSIEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFTS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVX6-1", "uniprot_id": "UBA3_DANRE", "id": "Q7ZVX6-1", "name": "NEDD8-activating enzyme E1 catalytic subunit", "aln": "MAEGEEPEKKRRRIEELN-EKMVVDGGSGDRSEWQGRWDHVRKFLERTGPFTHPDFEASTESLQFLLDTCKILVIGAGGLGCELLKDLALSGFR-HIHVVDMDTIDVSNLNRQFLFRPKDVGRPKAEVAADFVNDRVPGCSVVPHFKKIQDLDETFYRQFHIVVCGLDSVIARRWMNGMLLSLLIY-EDGVLDPSSIIPLIDGGTEGFKGNARVILPGMTACIDCTLELYPPQIN-FPMCTIASMPRLPEHCVEYVRMLLWPKEKPFGDGVVLDGDDPKHIQWVYQKSLERAAEFNIT--GVTYRLTQGVVKRIIPAVASTNAVIAAACATEVFKIATSAYVPLN--NYLVFNDVDGLYTYTFEAERKENCSACSQVPQDMQFTP--SAKLQEVLDYLTENASLQMKSPAITTTLD-GKNKTLYLQTVASIEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLKFIS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V6U8-1", "uniprot_id": "UBA3_DROME", "id": "Q9V6U8-1", "name": "Nedd8-activating enzyme E1 catalytic subunit", "aln": "---------------------MSVHSPNPGLILQSKRFNGLRNILEREGPFCKDGFAASSENLEFLQTKCQVLIIGAGGLGCELLKDLALMGFG-NLHVIDMDTIELSNLNRQFLFRRTDIGASKAECAARFINARVPTCRVTPHFKKIQDFDESFYQQFHLVVCGLDSIVARRWINGMLLSMLRYEEDGTIDTSSIVPMIDGGTEGFKGNARVILPGFTACIECTLDLFPPQVN-YPLCTIANTPRLPEHCIEYVKIIQWEKQNPFG--VPLDGDDPQHIGWIYERALERSNEFNIT--GVTYRLVQGVVKHIIPAVASTNAAIAAACALEVFKLATSCYDSMA--NYLNFNDLDGIYTYTYEAEKSENCLACSNTPQPLPIEDPNTTTLEDVIKLLCDSPRFQLKSPALTTVMKDGKRRTLYMSGVKSIEEATRKNLTQSLGELGLHDGQQLTVTDATSPSAMTLQLKYQSNEVEMV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99344-1", "uniprot_id": "UBA3_YEAST", "id": "Q99344-1", "name": "NEDD8-activating enzyme E1 catalytic subunit", "aln": "-------------------------------------------------------------------MDCKILVLGAGGLGCEILKNLTMLSFVKQVHIVDIDTIELTNLNRQFLFCDKDIGKPKAQVAAQYVNTRFPQLEVVAHVQDLTTLPPSFYKDFQFIISGLDAIEPRRFINETLVKLTLE-----SNYEICIPFIDGGTEGLKGHVKTIIPGITACWECSIDTLPSQQDTVPMCTIANNPRCIEHVVEYVSTIQYP---------DLNIESTADMEFLLEKCCERAAQFSISTEKLSTSFILGIIKSIIPSVSTTNAMVAATCCTQMVKIYNDLIDLENGNNFTLINCSEGCFMYSFKFERLPDCTVCSNSNSN---------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::*::********:**:*:: .* ::*::*:***:::******** .*:* .**: ** ::* *.* *..*.:.: : :**::*::::.***:: .**::* *:.: : . :*:*******:**:.:.*:**:*** :*::: *.* : *:****. ** ** :*** : : *: :.. .: :: ::. **: ::.* :: : *::* ***:*::*** :**.*. ::.*: .. *: :* :* : *::: *: :* .**: . ", "identical_positions": 104, "similar_positions": 113, "identity": "21.71%" }, { "cls_id": "homologset.agr.SGD:S000006271", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DCB8-1", "uniprot_id": "ISCA2_MOUSE", "id": "Q9DCB8-1", "name": "Iron-sulfur cluster assembly 2 homolog, mitochondrial", "aln": "-----MAASRALSLTAEAVRAVIPRRSGRLLAVFPRLLTRWETTSSI----PEAGEGQIRLTDSCVQRLLEITEGS-EFLRLQVEGGGCSGFQYKFSLDTVINPDDR----------------------VFEQGGARVVVDSDSLAFVKGAQVDFSQELIRSSFQVLNNPQAQQGCSCGSSFSVKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZSL2-1", "uniprot_id": "A0A8I5ZSL2_RAT", "id": "A0A8I5ZSL2-1", "name": "Iron-sulfur cluster assembly 2 homolog, mitochondrial", "aln": "-----MAAARALSLTVEAFGAPIPRRQGRLLAAFPRLLTRWETTSSI----PEAGEGQIRLTDSCVQRLLEITEGS-EFLRLQVEGGGCSGFQYKFSLDTVINPDDR----------------------VFEQGGARVVVDSDNLAYVKGAQVDFSQELIRSSFQVLNNPQAQQGCSCGSSFSIKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86U28-1", "uniprot_id": "ISCA2_HUMAN", "id": "Q86U28-1", "name": "Iron-sulfur cluster assembly 2 homolog, mitochondrial", "aln": "-----MAAAWGSSLTAATQRAVTPWPRGRLLTASLGPQARREASSSS----PEAGEGQIRLTDSCVQRLLEITEGS-EFLRLQVEGGGCSGFQYKFSLDTVINPDDR----------------------VFEQGGARVVVDSDSLAFVKGAQVDFSQELIRSSFQVLNNPQAQQGCSCGSSFSIKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P3Z0-1", "uniprot_id": "A0A8M1P3Z0_DANRE", "id": "A0A8M1P3Z0-1", "name": "Iron-sulfur cluster assembly 2 homolog, mitochondrial", "aln": "-----MSFARRLLVSAPKTASFHLLNLLSVRSCAAPLTSTSSNTEHQN---TSSTDAEVHLSQSCVKRLAEIMEKG-QYLRIAVEGGGCSGFQYKFSVDSVKNEDDR----------------------VFEKNGVGIVVDQDSLEFVKGSTVDFSQELIRASFQVLKNPQAEHGCSCGSSFSVKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC65-1", "uniprot_id": "Q9VC65_DROME", "id": "Q9VC65-1", "name": "Iron-sulfur cluster assembly 2 homolog, mitochondrial", "aln": "-----MAFLLRQVARSGLQRNLILMR-----------HATASTSANP--------ELSVQVSESCLKRLREICVDG-SFLRVTVEGGGCSGFQYKFDLDKQLNEDDR----------------------QFGEAEAKVVIDTVSLEYCSGATVDYHSELIRAGFRMVANPLAEQGCSCGSSFSIKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12425-1", "uniprot_id": "ISA2_YEAST", "id": "Q12425-1", "name": "Iron-sulfur assembly protein 2", "aln": "MQAKLLFTRLNFRRPSTTLRQFPLTCFLFHSKAFYSDLVTKEPLITPKRIINKTPGLNLSISERASNRLAEIYRNSKENLRISVESGGCHGFQYNLTLEPATKPDIKNDVKDKEFSDDLDDDDSKDIIYVLPEDKGRVIIDSKSLNILNNTTLTYTNELIGSSFKIING-SLKSSCGCGSSFDIEN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .: ::: . :** ** . . **: **.*** ****:: :: : * : : : :::* .* ..: : : .*** :.*::: . : .*.*****.:: ", "identical_positions": 28, "similar_positions": 43, "identity": "15.05%" }, { "cls_id": "homologset.agr.SGD:S000006272", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VH37-1", "uniprot_id": "HDAC8_MOUSE", "id": "Q8VH37-1", "name": "Histone deacetylase 8", "aln": "---------------MEMPEEPANSGHSLPPVYIYSPEYVSICDSLVKVPKR-------------------------------ASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHT-----DAYLQHLQKVSQEGDEDH-----------------PDSIEYGLGYDCPATEGIFDYAAAIGGGTITAAQCLIDGKCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLR-RKFDRILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDMSDVGLGKGRYYSVNVPIQDGIQDEKYYHICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYVLQ--WQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAY------GPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B1WC68-1", "uniprot_id": "HDAC8_RAT", "id": "B1WC68-1", "name": "Histone deacetylase 8", "aln": "---------------MEIPEEPANSGHSLPPVYIYSPEYVSICDSLVKVPKR-------------------------------ASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHT-----DAYLQHLQKVSQEGDEDH-----------------PDSIEYGLGYDCPATEGIFDYAAAIGGGTITAAQCLIDGKCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLR-RKFDRILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDMSDVGLGKGRYYSVNVPIQDGIQDEKYYHICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYVLQ--WQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAY------GPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BY41-1", "uniprot_id": "HDAC8_HUMAN", "id": "Q9BY41-1", "name": "Histone deacetylase 8", "aln": "---------------MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKR-------------------------------ASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHT-----DAYLQHLQKVSQEGDDDH-----------------PDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLR-RKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQ--WQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAY------GPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXM0-1", "uniprot_id": "HDAC8_DANRE", "id": "Q7SXM0-1", "name": "Histone deacetylase 8", "aln": "--------------MSEKSDSNDDKSRTRSVVYVYSPEYIQTCDSLSKVPNR-------------------------------ASMVHSLIEAYGLLKYMRVVKPHVASIEEMAVFHT-----DSYLQHLHKISQDGDNDD-----------------PQSADFGLGYDCPVVEGIFDYAAAVGGATLTAAQNLLDGKCDVAINWAGGWHHAKKDEASGSCYVNDAVLGILKLR-EKYDRVLYVDVDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVTDTGLGKGRWYAVNVPFEDGVRDDRYCQTFTSVMQEVKALFNPEAVVMQLGADTMAGDPMCSFNMTPVGVAKCLTYILG--WELPTLLLGGGGYNLANTARCWTYLTGTVLGQTLSSEIPDHEFFTEY------GPDYSLEISPSCRPDRNESQHLERVISTIKGNLKNVV-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12214-1", "uniprot_id": "HOS1_YEAST", "id": "Q12214-1", "name": "Histone deacetylase HOS1", "aln": "MSKLVISTSIFQSQVADLLPCNNHQKSQLTYSLINAYDLLQHFDEVLTFPYARKDDLLEFHSKSYIDYLINGRFNKMMAQDVNNPMVESKWSELSELADNWNEKIDYNPSQDLQRFTTRENLYNYYLNHSQALENNMDCINNSEVPTNDKPTDTYILNSETKQYNLEGDCPIFSYLPMYCQVITGATLNLLDHLSPTERLIGINWDGGRHHAFKQRASGFCYINDVVLLIQRLRKAKLNKITYVDFDLHHGDGVEKAFQYSKQIQTISVHLYEPGFFPGTGSLSDSRKDKN---VVNIPLKHGCDDNYLELIASKIVNPLIERHEPEALIIECGGDGLLGDRFNEWQLTIRGLSRIIINIMKSYPRAHIFLLGGGGYNDLLMSRFYTYLTWCVTKQFSNLRCGDNNSFQIDPFDVCDGDDSEQFIREHDLVEMYNEENYQYWIYEMEGSSRMKMLRNDNKDRDMVELMKFYEL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. : : : :. *.: ..* .**.* . . * . . ::: * * : **:* : :.:: * . .:: ::.* *** . : *. .: *.*:. : * :.*** ** *** *:.*** **:**.** * :** * ::: ***.*********.**.::.:: *:*:* :.********.::* .*. **:*::.* *: .::: : .:*:*:::: *.* : ** : .:::* *:.: : :: . ::******* :* :**** : : . . *:: * * * * : : .. : : ::*. : : ", "identical_positions": 100, "similar_positions": 123, "identity": "21.14%" }, { "cls_id": "homologset.agr.SGD:S000006273", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L6G0-1", "uniprot_id": "A0ABK0L6G0_RAT", "id": "A0ABK0L6G0-1", "name": "Spermidine synthase", "aln": "---------------------ME-GPSPLLAP--AAIREGWFRETCS-LWPGQALSLQVEQLLHQRRSRYQDILVFRSKTYG----------------------NVLVLDSVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDG-------------SVVQCEIDEDVIE--------------------VSKKFLPGMAVGYSSSKLTLHVGDGFEFMKQNQDAFDVIIT--------------------------------------------------------------DSSDPMGP----------------AESLFKESCYQLMK-------------------TALKEDGILRC-------QGECQWLHLDLIKEMRHFCKSLFPVVSYAYCTIPTYPSGQIGFMLCSK-NPSTNFREPVQQLTQVQV--------------EQMQLKYYNSDMHRAAFVLPEFTPKALNDIS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64674-1", "uniprot_id": "SPEE_MOUSE", "id": "Q64674-1", "name": "Spermidine synthase", "aln": "---------------------MEPGPDGPAAPGPAAIREGWFRETCS-LWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYG----------------------NVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIE--------------------VSKKFLPGMAVGFSSSKLTLHVGDGFEFMKQNQDAFDVIIT--------------------------------------------------------------DSSDPMGP----------------AESLFKESYYQLMK-------------------TALKEDGILCC-------QGECQWLHLDLIKEMRHFCKSLFPVVDYAYCSIPTYPSGQIGFMLCSK-NPSTNFREPVQQLTQAQV--------------EQMQLKYYNSDMHRAAFVLPEFTRKALNDIS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19623-1", "uniprot_id": "SPEE_HUMAN", "id": "P19623-1", "name": "Spermidine synthase", "aln": "---------------------MEPGPDGPAASGPAAIREGWFRETCS-LWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYG----------------------NVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQ--------------------VSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIIT--------------------------------------------------------------DSSDPMGP----------------AESLFKESYYQLMK-------------------TALKEDGVLCC-------QGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCSK-NPSTNFQEPVQPLTQQQV--------------AQMQLKYYNSDVHRAAFVLPEFARKALNDVS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12074-1", "uniprot_id": "SPEE_YEAST", "id": "Q12074-1", "name": "Spermidine synthase SPE3", "aln": "------------------------MAQEITHP---TIVDGWFREISDTMWPGQAMTLKVEKVLHHEKSKYQDVLIFKSTTYG----------------------NVLVLDNVIQATERDEFAYQEMIAHLALNSHPNPKKVLVIGGGDGGVLREVVKHDSVEEAWLCDIDEAVIR--------------------LSKEYLPEMAASYSHPKVKTHIGDGFQFLRDYQNTFDVIIT--------------------------------------------------------------DSSDPEGP----------------AETLFQKEYFQLLN-------------------SALTEKGVITT-------QAESMWIHLPIIKDLKKACSEVFPVAEYSFVTIPTYPTGTIGFMVCSK-DKTCNVKKPLREISDEKE--------------AEL-YRYYNKKIHEASFVLPTWAAKELN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VHA1-1", "uniprot_id": "Q9VHA1_DROME", "id": "Q9VHA1-1", "name": "", "aln": "---------------------------------MDSLNNGWFSELQADLWPGQSFSLKVKEVIHKEKSRFQDIQIVETETYG----------------------RCLILDGIIQCTARDEFSYQEMISFLPLCAHPNPKKVLIVGGGDGGVAREVVKHPLVEEVHQVEIDDRVVE--------------------LSKQYLPAMACGFANEKLKLTIGDGFDYMKKHKNEFDVIIT--------------------------------------------------------------DSSDPIGP----------------AVSLFQESYYELMK-------------------HALKDDGIVCS-------QGGSFWLDLDYIKKTMSGCKEHFAKVAYAVTSVPSYPCGHIGFVMGSL-NKNQDFATP--KLGKSEI--------------DSIDLRYYSSEVHSAAFALPRWVQKHFYE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9JJS8-1", "uniprot_id": "MASP2_RAT", "id": "Q9JJS8-1", "name": "Mannan-binding lectin serine protease 2", "aln": "MRLLIVLGLLWSLVATLLGSKWPEPVFGRLVSLGFPEKYGNHQDRSWTLTAPPGFRLRLYFTHFNLELSYRCEYDFVKLTSGTKVLATLCGQESTDTERAPGNDTFYSLGPSLKVTFHSDYSNEKPFTGFEAFYAAEDVDECRTSLGDSVPCDHYCHNYLGGYYCSCRVGYILHQNKHTCSALCSGQVFTGRSGFLSSPEYPQPYPKLSSCAYNIRLEEGFSITLDFVESFDVEMHPEAQCPYDSLKIQTDKREYGPFCGKTLPPRIETDSNKVTITFTTDESGNHTGWKIHYTSTAQPCPDPTAPPNGHISPVQATYVLKDSFSVFCKTGFELLQGSVPLKSFTAVCQKDGSWDRPIPECSIIDCGPPDDLPNGHVDYITGPEVTTYKAVIQYSCEETFYTMSSNGKYVCEADGFWTSSKGEKSLPVCKPVCGLSTHTSGGRIIGGQPAKPGDFPWQVLLLGETTAAGALIHDDWVLTAAHAVYGKTEAMSSLDIRMGILKRLSLIYTQAWPEAVFIHEGYTHGAGFDNDIALIKLKNKVTINRNIMPICLPRKEAASLMKTDFVGTVAGWGLTQKGFLARNLMFVDIPIVDHQKCATAYTKQPYPGAKVTVNMLCAGLDRGGKDSCRGDSGGALVFLDNETQRWFVGGIVSWGSINCGGSEQYGVYTKVTNYIPWIENIINNF", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . : : . .: *:: .: . :: . . * * *. :: * :.::: :: :: : .: . . **. :. : . :*. * : . : :**. . : *** : ..** .* : ::* : ::*:: .: : .:: :. :: :. . . *: : .* ** * : . . * : .. .:: :. . ", "identical_positions": 26, "similar_positions": 88, "identity": "3.8%" }, { "cls_id": "homologset.agr.SGD:S000006276", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZUV9-1", "uniprot_id": "D3ZUV9_RAT", "id": "D3ZUV9-1", "name": "CCR4-NOT transcription complex subunit 3", "aln": "MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHN--AANANQKEKYEADLKKEIKKLQRLRDQIKTWVASNEIKDKR-QLIENRKLIETQMERFKVVERETKTKAYSKEGLG-LAQKVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDKQDRIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPATSALSSTPGNNGASTPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPNASGPSNAQPRPPSAQPSGGSGGGSGG--SSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVALSSSGGSSASSQALGPTSGPHNPAPSTLKESSTAAPSGAGSVASGSGNNSGGPSLLVPLPVNPPSSPTPSFSEAKAAGTLLNGPPQFSTTPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTDRDIILSSTSAPPTSSQPPLQLSEVNIPLSLGVCPLGPVSLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKK-QSWRFHTKYMMWFQRHEEPKTITDEFEQISAPLFVHSLTTFFPGQGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K0V4-1", "uniprot_id": "CNOT3_MOUSE", "id": "Q8K0V4-1", "name": "CCR4-NOT transcription complex subunit 3", "aln": "MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHN--AANANQKEKYEADLKKEIKKLQRLRDQIKTWVASNEIKDKR-QLIENRKLIETQMERFKVVERETKTKAYSKEGLG-LAQKVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDKQDRIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPTTSALSSTPGNNGASTPAAPTSALGPKASPAPSHNSGTPAPYAQAVAPPNASGPSNAQPRPPSAQPSGGSGGGSGG--SSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVTLSSSGGSSASSQALGPTSGPHNPAPSTSKESSTAAPSGAGNVASGSGNNSGGPSLLVPLPVNPPSSPTPSFSEAKAAGTLLNGPPQFSTTPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTDRDIILSSTSAPPTSSQPPLQLSEVNIPLSLGVCPLGPVSLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKK-QSWRFHTKYMMWFQRHEEPKTITDEFE-----------------QGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75175-1", "uniprot_id": "CNOT3_HUMAN", "id": "O75175-1", "name": "CCR4-NOT transcription complex subunit 3", "aln": "MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHN--AANANQKEKYEADLKKEIKKLQRLRDQIKTWVASNEIKDKR-QLIDNRKLIETQMERFKVVERETKTKAYSKEGLG-LAQKVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDKQDRIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVCPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKK-QSWRFHTKYMMWFQRHEEPKTITDEFE-----------------QGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12514-1", "uniprot_id": "NOT5_YEAST", "id": "Q12514-1", "name": "General negative regulator of transcription subunit 5", "aln": "-MSQRKLQQDIDKLLKKVKEGIEDFDDIYEKFQSTDPSNSSHREKLESDLKREIKKLQKHRDQIKTWLSKEDVKDKQSVLMTNRRLIENGMERFKSVEKLMKTKQFSKEALTNPDIIKDPKELKKRDQVLFIHDCLDELQKQLEQYEAQEN----------------------EEQTERHEFHIANLENILKKLQNNEMDPEPVEEFQDDIKYYVENNDDPDFIEYDTIYEDMGCEIQPSSSNNEAP---------------KEGNNQTSLSSIRSS------------KKQERSPKKKAPQ-------RDVSISDRATTPIAP-----GVESASQSISSTP------TPVSTDTPLHTVKDDSIKFDN-----------------------------------------------------------------STLGTPTTHVSMKKKESENDSEQQLNFPPDRTDEIRKTIQHDVETN--------------------------------------AAFQNPLFNDELKYWLDSKRYLMQPLQEMSPKMVSQLESSLLNCPDS------LDADSPCLYTKPLSLPHPTSIFFPNEPIRFVYPYDVPLNLTNNENDTDNKFGKDSKAKSKKDDDIYSRTSLAR---------------------IFMKFDLDTLFFIFYHYQGSYEQFLAARELFKNRNWLFNKVDRCWYYKEIEKLPPGMGKSE----------------EESWRYFDYKKSWLARRCGNDFVYNEEDFEKL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:**** :**: ****.**:*:*:**::*::. .:*:.::** *:***:******: *******::.:::***: *: **:***. ***** **: *** :***.* ** : :*.: :: : :* *: *::*:*:: : :.: *:*.:*: **.**: *:*:.: :.:.:::**::***:..:**** * : :*:*:. * *.: :* . .. ** *.* .* **: **...:..* : * .::. :* .* * .::.::*:** :*.:. :.* . . : ..:. *.:. ..:.*::... ... *.* *. ... : .* :. : * ..*:*. :: .: :**..:.. ** :: * . * .. : * * * .: * *: : *: **::: : : .: .*. * *.* :: ::. :*******: :*: *:***: * * :.* *:. *: :. * . . : :: ****:* :: * * *. : ..* ", "identical_positions": 165, "similar_positions": 213, "identity": "21.29%" }, { "cls_id": "homologset.agr.SGD:S000006277", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P41498-1", "uniprot_id": "PPAC_RAT", "id": "P41498-1", "name": "Low molecular weight phosphotyrosine protein phosphatase", "aln": "-MAEVGSKSVLFVCLGNICRSPIAEAVFRKLVTDENVSDNW-RIDSAATSTYEVGNPPDYRGQNCMKKHGIHMQHIARQITREDFATFDYILCMDESNLRDLNRKSNQVKNC-KAKIELLGSYDPQK---QLIIEDPYYGN-DSDFEVVYQQCLRCCKAFLEKTH----------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D358-1", "uniprot_id": "PPAC_MOUSE", "id": "Q9D358-1", "name": "Low molecular weight phosphotyrosine protein phosphatase", "aln": "-MAEVGSKSVLFVCLGNICRSPIAEAVFRKLVTDEKVSDNW-RIDSAATSTYEVGNPPDYRGQNCMRKHGIHMQHIARQITKEDFATFDYILCMDESNLRDLNRKSNQVKNC-KAKIELLGSYDPQK---QLIIEDPYYGN-DSDFEVVYQQCLRCCKAFLEKTY----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24666-1", "uniprot_id": "PPAC_HUMAN", "id": "P24666-1", "name": "Low molecular weight phosphotyrosine protein phosphatase", "aln": "-MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENW-RVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTC-KAKIELLGSYDPQK---QLIIEDPYYGN-DSDFETVYQQCVRCCRAFLEKAH----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40347-1", "uniprot_id": "PPAL_YEAST", "id": "P40347-1", "name": "Low molecular weight phosphotyrosine protein phosphatase", "aln": "MTIEKPKISVAFICLGNFCRSPMAEAIFKHEVEKANLENRFNKIDSFGTSNYHVGESPDHRTVSICKQHGVKINHKGKQIKTKHFDEYDYIIGMDESNINNLKK--IQPEGS-KAKVCLFGDWNTNDGTVQTIIEDPWYGD-IQDFEYNFKQITYFSKQFLKKEL----------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P82891-1", "uniprot_id": "PPAC2_DROME", "id": "P82891-1", "name": "Low molecular weight phosphotyrosine protein phosphatase 2", "aln": "MGKRSQKSSVLMVCVGNLCRSPIAEAVMRDLVARAGLQGEW-HVESAGIEDWHSGHQPDERALNVLARHNIEYNGKARVLAPEDFLEFDYIFAMDLSNLAALRR--MAPKGT-TAKLLILGNFGLKPD--ERIIEDPYYDIGEASFEEIYRQCSIACRNFLKQARLKQIM-----------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P82890-1", "uniprot_id": "PPAC1_DROME", "id": "P82890-1", "name": "Low molecular weight phosphotyrosine protein phosphatase 1", "aln": "MVRK-----VLMICLGNICRSPIAEVVMVDTLEKANVK-DV-EVDSAAIGGWHVGNRADPRAISTLQKHGLKCTHIVRQIRKQDFSEFDYIFGMDEDNMSELRR--LAPKGS-KAELLMLGDFGLEKK--NRIIEDPYYERGAEGFETAYQQCVVACAAFMKERLQK--------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8ING6-1", "uniprot_id": "Q8ING6_DROME", "id": "Q8ING6-1", "name": "", "aln": "-------MKVLFVCIGNTCRSPMAEAILKHLVVKRNLQDWY--VDSAGLRSWNVGLEPQARGQQLLKQHGLKTNHLGRMISAQDFYDFDYIFAMDNSNLLELEHMAASLTPSPTCKIQLLGSYIGRKE--DEIIEDPYFIQGMGGFNAAYLQILESCERFLQHYKSDDKELSLGS------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VE30-1", "uniprot_id": "Q9VE30_DROME", "id": "Q9VE30-1", "name": "Phosphotyrosine protein phosphatase I domain-containing protein", "aln": "----MTFKKILFVCMGNSCSSPMAEVIMQNLMVKTSLYWEV---DSAGLRTWNTGRRPNKRCLQILREHGLRSDHFCRQFTVNDFLYFDYVVAMDEAVFKELLLWAADNRAGKHCQVLLLSSFGKNGLP--AFIDSLSPTHKLKNFRSAYYQIKECCKQLILSQKVDIVKYELPSTDDDELYYSGKDNAPQDSAKANHLTETSHNNSGIYLLNTEIRSSGGLMSSSTDPSNSKTSMPSCSQGVQRKLCQKCGQKFLAAL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::*:** * **:**.:: . : : :* . :. * .: * . .*.: : : :.* :**:. ** : * .:: ::..: . :*:. .*. : * . :: ", "identical_positions": 21, "similar_positions": 47, "identity": "8.11%" }, { "cls_id": "homologset.agr.SGD:S000006278", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHE7-1", "uniprot_id": "D3ZHE7_RAT", "id": "D3ZHE7-1", "name": "transketolase", "aln": "-------MALARDAKLESDIFQALQDVANRLRIHSIRATCASSSGHPTSCCSAAEIMAVLFFHTMRYKQADPEHPDNDRFVLSKGHAAPILYAVWVEVGR-ICESDLLNLRKIHCDLEGHPTPRLSFVDVATGSLGQGLGAACGMAYTGKYFDKASYR---------VFCLMGDGESSEGSVWEALAFASHYKLDNLLAIFDVNRLGQSGTAPLEHCTDIYETRCQAFGWNTYVVDG--HDVEALCQAFWKAAQVKNKPTALIAKTFKGRGIPNVEDAENWHGKPMPKDRVDGIVK-----------------------LIESQIQTNRNLTPKPP--VEDSPRISISNTKMTS----------LPAYKLGD-MIATREAYGVALAKLGHSNQRVIVLDGDTKNSTFS---EVFKKEHPE--------RFIECFIAEQNMVSVALGCATRGR-TIAFVSTFAAFLTRAFDQIRMGAISQTNVNFVGSHCGVSIGEDGPSQMALEDLAMFRSIPNCTIFYPSDAVSTEHAIYLAANTKG-MCFIRTTRPKLAVIYTSEENFVIGQAKVIRHSADDKVTVVGAGVTLHEALEAADELSQQGISIRVIDP-----FTIKPLDASTIIQSAKATGGQIITVEDHYREGGIGEAVCAAISREPDIVVHQLAVTEVPRSGKPSELLDMFGISARHIIAAVKDTVMK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D4D4-1", "uniprot_id": "TKTL2_MOUSE", "id": "Q9D4D4-1", "name": "Transketolase-like protein 2", "aln": "-------MALARDAKLESDTLQVLQDVANRLRIHSIRATCACSSGHPTSCCSVAEIMAVLFFHTMRYKQADPEHPDNDRFVLSKGHAAPILYAVWVEVGR-ICESDLLNLRKIHCDLEGHPTPRLSFVDVATGSLGQGLGAACGMAYTGKYFDKASYR---------VFCLMGDGESSEGSVWEALAFASHYNLDNLVAIFDVNRLGQSGTAPLEHCTAVYEKRCQAFGWNTYVVDG--HDVEALCQAFWKAAQVKNKPTALIAKTFKGRGIPNVEDAENWHGKPMPKDRADGIVK-----------------------LIENRIQTNRNLTPKPP--IEDSPRISMSNTKMTS----------LPVYKLGD-MIATREAYGLALAKLGQSNQRVIVLDGDTKNSTFS---EVFKKEHPE--------RFIECFIAEQNMVSVALGCATRGR-TIAFVSTFAAFLTRAFDQIRMGAISQTNINFVGSHCGVSVGEDGPSQMALEDLAMFRSIPNCTVFYPSDAVSTEHAVYLAANTKG-MCFIRTTRPKTAVIYTAEENFVIGQAKVIRQSAVDKVTVIGAGVTLHEALVAAEELSQQGIFIRVIDL-----FTIKPLDAVTIIQSAKATGGQIITVEDHYREGGIGEAVCAAISREPDIVVRQLAVTEVPRSGKPSELLDMFGISARHIIAAVKDTVMK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0I9-1", "uniprot_id": "TKTL2_HUMAN", "id": "Q9H0I9-1", "name": "Transketolase-like protein 2", "aln": "--------MMANDAKPDVKTVQVLRDTANRLRIHSIRATCASGSGQLTSCCSAAEVVSVLFFHTMKYKQTDPEHPDNDRFILSRGHAAPILYAAWVEVGD-ISESDLLNLRKLHSDLERHPTPRLPFVDVATGSLGQGLGTACGMAYTGKYLDKASYR---------VFCLMGDGESSEGSVWEAFAFASHYNLDNLVAVFDVNRLGQSGPAPLEHGADIYQNCCEAFGWNTYLVDG--HDVEALCQAFWQASQVKNKPTAIVAKTFKGRGIPNIEDAENWHGKPVPKERADAIVK-----------------------LIESQIQTNENLIPKSP--VEDSPQISITDIKMTS----------PPAYKVGD-KIATQKTYGLALAKLGRANERVIVLSGDTMNSTFS---EIFRKEHPE--------RFIECIIAEQNMVSVALGCATRGR-TIAFAGAFAAFFTRAFDQLRMGAISQANINLIGSHCGVSTGEDGVSQMALEDLAMFRSIPNCTVFYPSDAISTEHAIYLAANTKG-MCFIRTSQPETAVIYTPQENFEIGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLSQQGISVRVIDP-----FTIKPLDAATIISSAKATGGRVITVEDHYREGGIGEAVCAAVSREPDILVHQLAVSGVPQRGKTSELLDMFGISTRHIIAAVTLTLMK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99MX0-1", "uniprot_id": "TKTL1_MOUSE", "id": "Q99MX0-1", "name": "Transketolase-like protein 1", "aln": "MSEAEASSGMAHNAGPDEKTLQVLRDMANRLRIRSIKATNSSTTSYLIPCS-NAEIMSVLFFYTMRYKQEDPENPDNDRCILSKG---------------------------------------LPFVNVATGWPGQGLGAACGMAYTGKYFDQASYR---------VFCLLGDEESTEGSVWEAFAFASYYNLDNLMAIFDVNRIGHSSSMSVEHCIAIYQKRCEAFGWNTYVVDG--RDVKTLCHVFSQAAQVRGKPTAVVAKTFKARGMPNVEDAESWYGRPMPKERADAIVK-----------------------LIESQIQTNKILVPSPP--IEDSPQINIMNICMTS----------PPVYVADD-KVSTQRACGLALAKLGHENDRVIVLGSDTKNCNFS---DIFKKEHPE--------RFIQCCIAEQNMVNVALGCSTRDR-TIVFAYSFAAFFTRAFDQIRLGAISQININLIGCHCGVSTGDDNPYHMALEDLAMFRAIPNCVVFYPSDAVSTEHAVYLAANTKE-MCFIRTSQAETAIIYTTQETFQIGQAKVVRHSDNDKVIVIGAGVTLHEALVAAAELSKEDISIRVIDL-----FTIKPLDIATIISNAKATGGRIITVEDHYPEGGIGGAVCAAVSMEPNIVVHNLAVMDVPRSGRCNEALDFSGISSRHIIVAVKCILMT-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZPV2-1", "uniprot_id": "D3ZPV2_RAT", "id": "D3ZPV2-1", "name": "transketolase", "aln": "MSEAEASVGMAHDAGPDEKTLQVLRDMANRLRIRFIRTTSSSTTSYLTPCSSAAEIMSVLFFYTMRYKQEDPENPDNDRCILSKG---------------------------------------IPFVKVATGWPGQGLGAARGMAYTGKYFDQASYR---------VFCLLGDEESTEGSVWEAFAFASYYNLDNLMAIFDVNRIGHSSSMSVEHCVGIYQKRCEAFGWNTYVVDG--RNVETLCRVFSQAAQVRGKPTAVVAKTFKARGMPNVEDAESWHGRPMPKERADAIIK-----------------------LIESQIQSNKILVPSPP--IENSPQINIMDIHMAS----------PPAYVADD-MVSTQRACGLALAKLGHENDRVIVLDSDTENCNFS---DIFKKEHPE--------RFIQCYIAEQNMVNVALGCATRDR-IIAFACTFAAFFTRAFDQIRVGAISQININLIGCHCGVSTGDDNPYHMALEDLAMFRAIPNCIVFYPSDAVSTEHAIYLAANTKE-MCFIHTSQAETAIIYTTQETFEIGQAKVVRHSNDDKVIVIGAGVTLHEALVAADELSKEDISIRVIDL-----FTIKPLDSATIISNAKATGGRIVTVEDHYLEGGIGGAVCAAVSMEPNIVVHRLAVMDVPRSGRCNEALDFSGISSRHIIVAVKCILMN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51854-3", "uniprot_id": "TKTL1_HUMAN", "id": "P51854-3", "name": "Transketolase-like protein 1", "aln": "MADAEARAEFPEEARPDRGTLQVLQDMASRLRIHSIRATCSTSSGHPTSCSSSSEIMSVLFFYIMRYKQSDPENPDNDRFVLAKR---------------------------------------LSFVDVATGWLGQGLGVACGMAYTGKYFDRASYR---------VFCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRRCEAFGWNTYVVDG--RDVEALCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPMPRERADAIIK-----------------------LIESQIQTSRNLDPQPP--IEDSPEVNITDVRMTS----------PPDYRVGD-KIATRKACGLALAKLGYANNRVVVLDGDTRYSTFS---EIFNKEYPE--------RFIECFMAEQNMVSVALGCASRGR-TIAFASTFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALAANAKG-MCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDKVTVIGAGITVYEALAAADELSKQDIFIRVIDL-----FTIKPLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40142-1", "uniprot_id": "TKT_MOUSE", "id": "P40142-1", "name": "Transketolase", "aln": "---------MEGYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKALDPRNPHNDRFVLSKGHAAPILYAVWAEAGF-LPEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYR---------VYCMLGDGEVSEGSVWEAMAFAGIYKLDNLVAIFDINRLGQSDPAPLQHQVDIYQKRCEAFGWHTIIVDG--HSVEELCKAFG---QAKHQPTAIIAKTFKGRGITGIEDKEAWHGKPLPKNMAEQIIQ-----------------------EIYSQVQSKKKILATPP--QEDAPSVDIANIRMPT----------PPSYKVGD-KIATRKAYGLALAKLGHASDRIIALDGDTKNSTFS---ELFKKEHPD--------RFIECYIAEQNMVSIAVGCATRDR-TVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPMSTVFYPSDGVATEKAVELAANTKG-ICFIRTSRPENAIIYSNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAESLKKDKISIRVLDP-----FTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSAAVVGEPGVTVTRLAVSQVPRSGKPAELLKMFGIDKDAIVQAVKGLVTKG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50137-1", "uniprot_id": "TKT_RAT", "id": "P50137-1", "name": "Transketolase", "aln": "---------MEGYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKALDPRNPHNDRFVLSKGHAAPILYAVWAEAGF-LPEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYR---------VYCMLGDGEVSEGSVWEAMAFAGIYKLDNLVAIFDINRLGQSDPAPLQHQVDVYQKRCEAFGWHAIIVDG--HSVEELCKAFG---QAKHQPTAIIAKTFKGRGITGIEDKEAWHGKPLPKNMAEQIIQ-----------------------EIYSQVQSKKKILATPP--QEDAPSVDIANIRMPT----------PPNYKVGD-KIATRKAYGLALAKLGHASDRIIALDGDTKNSTFS---ELFKKEHPD--------RFIECYIAEQNMVSIAVGCATRDR-TVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPMSTVFYPSDGVATEKAVELAANTKG-ICFIRTSRPENAIIYSNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAEMLKKEKIGVRVLDP-----FTIKPLDKKLILDCARATKGRILTVEDHYYEGGIGEAVSAVVVGEPGVTVTRLAVSQVPRSGKPAELLKMFGIDKDAIVQAVKGLVTKG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29401-1", "uniprot_id": "TKT_HUMAN", "id": "P29401-1", "name": "Transketolase", "aln": "---------MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFVLSKGHAAPILYAVWAEAGF-LAEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYR---------VYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDG--HSVEELCKAFG---QAKHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQ-----------------------EIYSQIQSKKKILATPP--QEDAPSVDIANIRMPS----------LPSYKVGD-KIATRKAYGQALAKLGHASDRIIALDGDTKNSTFS---EIFKKEHPD--------RFIECYIAEQNMVSIAVGCATRNR-TVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKG-ICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDP-----FTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLITKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VVP4-1", "uniprot_id": "Q9VVP4_DROME", "id": "Q9VVP4-1", "name": "transketolase", "aln": "----------MSNAKLDSKVVQNLKDVAQKLRIHSITSTQAAKSGHPTSCASLAEIMTVLFFQQMRLNLKHPRDPSSDRLVLSKGHAAPILYAVWAEAGL-FPVEELRNLRKVDSDLEGHPTPRLSFVDVSTGSLGQGISVAAGMAYVGKHLDKADYR---------TYVIVGDGEATEGAVWESLHFAGHYCLDNLCVIFDMNKIFCS---DIGTEMEVYRERLDAFGFNALVLNG--HDIDELAKAFINAASTKGKPTALLARTTKGKDFLGIEGIEEMHAQPLGKRAESAIKH-----------------------LQMKIANPNVRLTPKKVGKCGHAPEVHINNIMLCS----------PPNYRLGD-SVAPRLAYGTALAKIAADNPRVIALDGDTKNSTYA---DKMRNAFPE--------RFIECFTAQQNLVGVAVGATCRRR-TVAFVSTYATFFTRAFDQIRMGAISHTNVNFAGSHCGCSIGEDGPSQMGLEDMAMFRSIPGSTVFYPTDAVSTERAVELAANTKG-VCYIRTTYPSTTVIYNNDEVFAVGLGKVVRQKPSDEVLLIGAGVTLYECLAAAERLEEDCITARVIDP-----FTVKPLDVGLIVKHGKLCRGRIVVVEDHYQQGGLGEAVLSALADYRNFVVKHLYITTVPRSGPPAVLLDMFGVSSRNIYKASLAIMKK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VHN7-1", "uniprot_id": "Q9VHN7_DROME", "id": "Q9VHN7-1", "name": "transketolase", "aln": "----------MSYHKPEAKTVQDLKDLAQKLRIHSINATQASKSGHPTSCASIAEIMSVLFFQQLRLNLKHPRDPSSDRFILSKGHAAPILYAAWAEAGL-FPIADLNNLRKIDSDLEGHPTPRLNFIDVGTGSLGQGVAVGAGMAYVGKNFDKADYR---------TYVVVGDGESAEGSIWESLHFAGHYKLDNLCVIFDVNRLGQSEATSLQHKLDVYRDRLEAFGFNAVVVDG--HDVEELSKAFHCAAITKNKPTAIIAKTFKGRDFPNIEDLDNWHGKPLGDKAAEVVKH-----------------------LEGLIVNKNVKLTPKPVPKTGAAPDVDINNIKLSS----------PPAYKLGD-SIATRLAYGTALAKIGQNNLRVVALDGDTKNSTFS---DKLKNLDPQ--------RYIECFIAEQNLVGVAVGAACRRR-TVAFVSTFATFFTRAFDQIRMGAISQTNVNFVGSHCGCSIGEDGPSQMGLEDIAMFRTIPGSTIFYPSDAVSTERAVELAANTKG-VCFIRTSRPNTCVIYDNEEPFTIGRGKVVRQKSSDEVLLIGAGITLYECLAAADQLEKNCITVRVIDP-----FTVKPLDAELIIEHGKQCGGRVVVVEDHYQQGGLGEAVLSALAGERNFVVKHLYVPTVPRSGPPSVLIDMFGISARHVVNAVNEILKD-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23254-1", "uniprot_id": "TKT1_YEAST", "id": "P23254-1", "name": "Transketolase 1", "aln": "----------------MTQFTDIDKLAVSTIRILAVDTVSKANSGHPGAPLGMAPAAHVLWS-QMRMNPTNPDWINRDRFVLSNGHAVALLYSMLHLTGYDLSIEDLKQFRQLGSRTPGHPEFELPGVEVTTGPLGQGISNAVGMAMAQANLAATYNKPGFTLSDNYTYVFLGDGCLQEGISSEASSLAGHLKLGNLIAIYDDNKITIDGATSISFDEDVAKR-YEAYGWEVLYVENGNEDLAGIAKAIAQAKLSKDKPTLIKMTTTIGYGSLHAG-SHSVHGAPLKADDVKQLKSKFGFNPDKSFVVPQEVYDHYQKTILKPGVEANNKWNKLFSEYQKKFPELGAELARRLSGQLPANWESKLPTYTAKDSAVATRKLSETVLEDVYNQLPELIGGSADLTPSNLTRWKEALDFQPPSSGSGNYSGRYIRYGIREHAMGAIMNGISAFGANYKPYGGTFLNFVSYAAGAVRLSALSGHPVIWVATHDSIGVGEDGPTHQPIETLAHFRSLPNIQVWRPADGNEVSAAYKNSLESKHTPSIIALSRQNLPQLEGSSIESASKGGYVLQDVANPDIILVATGSEVSLSVEAAKTLAAKNIKARVVSLPDFFTFDKQPLEYRLSVLPDNVPIMSVEVLATTCWGKYAHQSFGIDRFGASGKAPEVFKFFGFTPEGVAERAQKTIAFYKGDKLISPLKKAF--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .. :** : :. :. . : **: :: : .* ** :*:. .* ** ***:. . *** . : : : .: .:.* ** *: :*. *.** .: * *:: . : . :*:*:.. ::. ..: :.:.: : :** : * . . . :. *: . : : . * : : * * * ::.: .* .: .:: ..* .. : : : *. *:*. :: : : * : : :: *.: * . :*:..:: : . * . . *:*. : :* :* **::* :: *:*. .. * : ::* . * : . : . . *: . .: ::.:* : .: ** * . * **:. * :**: : . : .: :. . : . .. * . .. : ", "identical_positions": 71, "similar_positions": 170, "identity": "10.13%" }, { "cls_id": "homologset.agr.SGD:S000006283", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P11717-1", "uniprot_id": "MPRI_HUMAN", "id": "P11717-1", "name": "Cation-independent mannose-6-phosphate receptor", "aln": "MGAAAGRSPHLGPAPARRPQRSLLLLQLLLLVAAPGSTQAQAAPFPELCSYTWEAVDTKNNVLYKINICGSVDIVQCGPSSAVCMHDLKTRTYHSVGDSVLRSATRSLLEFNTTVSCDQQGTNHRVQSSIAFLCGKTLGTPEFVTATECVHYFEWRTTAACKKDIFKANKEVPCYVFDEELRKHDLNPLIKLSGAYLVDDSDPDTSLFINVCRDIDTLRDPGSQLRACPPGTAACLVRGHQAFDVGQPRDGLKLVRKDRLVLSYVREEAGKLDFCDGHSPAVTITFVCPSERREGTIPKLTAKSNCRYEIEWITEYACHRDYLESKTCSLSGEQQDVSIDLTPLAQSGGSSYISDGKEYLFYLNVCGETEIQFCNKKQAAVCQVKKSDTSQVKAAGRYHNQTLRYSDGDLTLIYFGGDECSSGFQRMSVINFECNKTAGNDGKGTPVFTGEVDCTYFFTWDTEYACVKEKEDLLCGATDGKKRYDLSALVRHAEPEQNWEAVDGSQTETEKKHFFINICHRVLQEGKARGCPEDAAVCAVDKNGSKNLGKFISSPMKEKGNIQLSYSDGDDCGHGKKIKTNITLVCKPGDLESAPVLRTSGEGGCFYEFEWHTAAACVLSKTEGENCTVFDSQAGFSFDLSPLTKKNGAYKVETKKYDFYINVCGPVSVSPCQPDSGACQVAKSDEKTWNLGLSNAKLSYYDGMIQLNYRGGTPYNNERHTPRATLITFLCDRDAGVGFPEYQEEDNSTYNFRWYTSYACPEEPLECVVTDPSTLEQYDLSSLAKSEGGLGGNWYAMDNSGEHVTWRKYYINVCRPLNPVPGCNRYASACQMKYEKDQGSFTEVVSISNLGMAKTGPVVEDSGSLLLEYVNGSACTTSDGRQTTYTTRIHLVCSRGRLNSHPIFSLNWECVVSFLWNTEAACPIQTTTDTDQACSIRDPNSGFVFNLNPLNSSQGYNVSGIGKIFMFNVCGTMPVCGTILGKPASGCEAETQTEELKNWKPARPVGIEKSLQLSTEGFITLTYKGPLSAKGTADAFIVRFVCNDDVYSGPLKFLHQDIDSGQGIRNTYFEFETALACVPSPVDCQVTDLAGNEYDLTGLSTVRKPWTAVDTSVDGRKRTFYLSVCNPLPYIPGCQGSAVGSCLVSEGNSWNLGVVQMSPQAAANGSLSIMYVNGDKCGNQRFSTRITFECAQISGSPAFQLQDGCEYVFIWRTVEACPVVRVEGDNCEVKDPRHGNLYDLKPLGLNDTIVSAGEYTYYFRVCGKLSSDVCPTSDKSKVVSSCQEKREPQGFHKVAGLLTQKLTYENGLLKMNFTGGDTCHKVYQRSTAIFFYCDRGTQRPVFLKETSDCSYLFEWRTQYACPPFDLTECSFKDGAGNSFDLSSLSRYSDNWEAITGTGDPEHYLINVCKSLAPQAGTEPCPPEAAACLLGGSKPVNLGRVRDGPQWRDGIIVLKYVDGDLCPDGIRKKSTTIRFTCS-ESQVNSRPMFISAVEDCEYTFAWPTATACPMKSNEHDDCQVTNPSTGHLFDLSSLSGRAGFTAAYSEKGLVYMSICGENENCPPGVGACFGQTRISVGKANKRLRYVDQVLQLVYKDGSPCPSKSGLSYKSVISFVCRPEARPTNRPMLISLDKQTCTLFFSWHTPLACEQATECSVRNGSSIVDLSPLIHRTGGYEAYDESEDDASDTNPDFYINICQPLNPMHGVPCPAGAAVCKVPIDGPPIDIGRVAGPPILNPIANEIYLNFESSTPCLADKHFNYTSLIAFHCKRGVSMGTPKLLRTSECDFVFEWETPVVCPDEVRMDGCTLTDEQLLYSFNLSSLSTSTFKVTRDSRTYSVGVCTFAVGPEQGGCKDGGVCLLSGTKGASFGRLQSMKLDYRHQDEAVVLSYVNGDRCPPETDDGVPCVFPFIFNGKSYEECIIESRAKLWCSTTADYDRDHEWGFCRHSNSYRTSSIIFKCDEDEDIGRPQVFSEVRGCDVTFEWKTKVVCPPKKLECKFVQKHKTYDLRLLSSLTGSWSLVHNGVSYYINLCQKIYKGPLGCSERASICRRTTTGDVQVLGLVHTQKLGVIGDKVVVTYSKGYPCGGNKTASSVIELTCTKTVGRPAFKRFDIDSCTYYFSWDSRAACAVKPQEVQMVNGTITNPINGKSFSLGDIYFKLFRASGDMRTNGDNYLYEIQLSSITSSRNPACSGANICQVKPNDQHFSRKVGTSDKTKYYLQDGDLDVVFASSSKCGKDKTKSVSSTIFFHCDPLVEDGIPEFSHETADCQYLFSWYTSAVCPLGVGFDSENPGDDGQMHKGLSERSQAVGAVLSLLLVALTCCLLALLLYKKERRETVISKLTTCCRRSSNVSYKYSKVNKEEETDENETEWLMEEIQLPPPRQGKEGQENGHITTKSVKALSSLHGDDQDSEDEVLTIPEVKVHSGRGAGAESSHPVRNAQSNALQEREDDRVGLVRGEKARKGKSSSAQQKTVSSTKLVSFHDDSDEDLLHI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q06815-1", "uniprot_id": "MRL1_YEAST", "id": "Q06815-1", "name": "Mannose 6-phosphate receptor-like protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKRSSLIYLS-----------------------------CVLIITIP-------------------------------------------ILLHVYNGPGLSHEANEHRASHKQKRTLANPDKP--------------------------KSENDEDLFCAVTNPVTGSYIDLSQLSSTP------------------------------------------------------------------------------------------------------------------------------------NKLREGQKQISGNNKHESSKTKWSVRGWGYDTNFTLGICS----------SPVG------------------------------------------------------------------------------------------------------------------------------------------------EAESQQLSNLTGAFYVDQLNEN-------------------------------------------------------------------------NLVSIGDFST-----------------------------------RPALVGGSTAKKLT--------------LKYENGSMCPNGKDKKATLLNFVCDKEIQSKAQISYIGNLHNCSYFFEVRSIHACPT-SNKKNEVNVLGIFIG-IFAIFFLVEFAGRRWIYAKLN---------------------------------------------------------------------------------------------------------RHLKNDDELHDISPSLNEQPHWDLIEDGS---------------------------------------------------------------------------------------------------------------------------------------RWSKFFNGIIKTTRRFTKSLMRSLVRGRNSRQGGIRLRSSPSASSSSLANREFFRDMEAQNEIIDSLDINSHTTESDHPTLADNSV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: .* *: * : .:* :**. **.. : . ..: : .: : :.. .: :: .* * *:: :* :* ::*. *.*: ..* .: :::* .. ... * .. * . .* *.:*. *.** : *.* : :::* : . ** :* *:. :* ..*:***.. :* *** :*.:**:* **:* :.*.*. * * ::: :*. :.:*.* * : *** **:::: :* . * :* : * ** *:: . ::*...: *:** ::. :: ::.. . *.: .. :*.** . : . . ...*** : . *.:. *. ::.*: : . *. : *:.. . *. :*:.* ", "identical_positions": 89, "similar_positions": 157, "identity": "3.57%" }, { "cls_id": "homologset.agr.SGD:S000006284", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5VTE0-1", "uniprot_id": "EF1A3_HUMAN", "id": "Q5VTE0-1", "name": "Putative elongation factor 1-alpha-like 3", "aln": "--------------MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLK------AERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKN----------------------------------------MITGTSQADCAVLIVAAGVGEFEAG------------------------ISKNG-----------QTREHALLAYTLGVKQLIVG--VNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYN------------------PDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGN----------------------------------ASGTTLLEALDCILPPT-----------------RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKP-GMVVTFAP------------------------VNVTTEVKSVEMHHEALSEALPGDNVG------------------------------FKVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDCHMAHIACKFAELKE---------------------------------------------------------------------------KIDRRSGKKLEDGPKFLK---------------------SGDAAIVDMVPGKPMCVESFSDYP------------------PLGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK-------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P68104-1", "uniprot_id": "EF1A1_HUMAN", "id": "P68104-1", "name": "Elongation factor 1-alpha 1", "aln": "--------------MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLK------AERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKN----------------------------------------MITGTSQADCAVLIVAAGVGEFEAG------------------------ISKNG-----------QTREHALLAYTLGVKQLIVG--VNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYN------------------PDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGN----------------------------------ASGTTLLEALDCILPPT-----------------RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKP-GMVVTFAP------------------------VNVTTEVKSVEMHHEALSEALPGDNVG------------------------------FNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKE---------------------------------------------------------------------------KIDRRSGKKLEDGPKFLK---------------------SGDAAIVDMVPGKPMCVESFSDYP------------------PLGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK-------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10126-1", "uniprot_id": "EF1A1_MOUSE", "id": "P10126-1", "name": "Elongation factor 1-alpha 1", "aln": "--------------MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLK------AERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKN----------------------------------------MITGTSQADCAVLIVAAGVGEFEAG------------------------ISKNG-----------QTREHALLAYTLGVKQLIVG--VNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYN------------------PDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGS----------------------------------ASGTTLLEALDCILPPT-----------------RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKP-GMVVTFAP------------------------VNVTTEVKSVEMHHEALSEALPGDNVG------------------------------FNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKE---------------------------------------------------------------------------KIDRRSGKKLEDGPKFLK---------------------SGDAAIVDMVPGKPMCVESFSDYP------------------PLGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK-------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62630-1", "uniprot_id": "EF1A1_RAT", "id": "P62630-1", "name": "Elongation factor 1-alpha 1", "aln": "--------------MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLK------AERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKN----------------------------------------MITGTSQADCAVLIVAAGVGEFEAG------------------------ISKNG-----------QTREHALLAYTLGVKQLIVG--VNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYN------------------PDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGS----------------------------------ASGTTLLEALDCILPPT-----------------RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKP-GMVVTFAP------------------------VNVTTEVKSVEMHHEALSEALPGDNVG------------------------------FNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKE---------------------------------------------------------------------------KIDRRSGKKLEDGPKFLK---------------------SGDAAIVDMVPGKPMCVESFSDYP------------------PLGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK-------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62631-1", "uniprot_id": "EF1A2_MOUSE", "id": "P62631-1", "name": "Elongation factor 1-alpha 2", "aln": "--------------MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLK------AERERGITIDISLWKFETTKYYITIIDAPGHRDFIKN----------------------------------------MITGTSQADCAVLIVAAGVGEFEAG------------------------ISKNG-----------QTREHALLAYTLGVKQLIVG--VNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYN------------------PATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGN----------------------------------ASGVSLLEALDTILPPT-----------------RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRP-GMVVTFAP------------------------VNITTEVKSVEMHHEALSEALPGDNVG------------------------------FNVKNVSVKDIRRGNVCGDSKADPPQEAAQFTSQVIILNHPGQISAGYSPVIDCHTAHIACKFAELKE---------------------------------------------------------------------------KIDRRSGKKLEDNPKSLK---------------------SGDAAIVEMVPGKPMCVESFSQYP------------------PLGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTKSAQKAQKAGK------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62632-1", "uniprot_id": "EF1A2_RAT", "id": "P62632-1", "name": "Elongation factor 1-alpha 2", "aln": "--------------MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLK------AERERGITIDISLWKFETTKYYITIIDAPGHRDFIKN----------------------------------------MITGTSQADCAVLIVAAGVGEFEAG------------------------ISKNG-----------QTREHALLAYTLGVKQLIVG--VNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYN------------------PATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGN----------------------------------ASGVSLLEALDTILPPT-----------------RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRP-GMVVTFAP------------------------VNITTEVKSVEMHHEALSEALPGDNVG------------------------------FNVKNVSVKDIRRGNVCGDSKADPPQEAAQFTSQVIILNHPGQISAGYSPVIDCHTAHIACKFAELKE---------------------------------------------------------------------------KIDRRSGKKLEDNPKSLK---------------------SGDAAIVEMVPGKPMCVESFSQYP------------------PLGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTKSAQKAQKAGK------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q05639-1", "uniprot_id": "EF1A2_HUMAN", "id": "Q05639-1", "name": "Elongation factor 1-alpha 2", "aln": "--------------MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLK------AERERGITIDISLWKFETTKYYITIIDAPGHRDFIKN----------------------------------------MITGTSQADCAVLIVAAGVGEFEAG------------------------ISKNG-----------QTREHALLAYTLGVKQLIVG--VNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYN------------------PATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGN----------------------------------ASGVSLLEALDTILPPT-----------------RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRP-GMVVTFAP------------------------VNITTEVKSVEMHHEALSEALPGDNVG------------------------------FNVKNVSVKDIRRGNVCGDSKSDPPQEAAQFTSQVIILNHPGQISAGYSPVIDCHTAHIACKFAELKE---------------------------------------------------------------------------KIDRRSGKKLEDNPKSLK---------------------SGDAAIVEMVPGKPMCVESFSQYP------------------PLGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTKSAQKAQKAGK------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q92005-1", "uniprot_id": "EF1A_DANRE", "id": "Q92005-1", "name": "Elongation factor 1-alpha", "aln": "--------------MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLK------AERERGITIDIALWKFETSKYYVTIIDAPGHRDFIKN----------------------------------------MITGTSQADCAVLIVAGGVGEFEAG------------------------ISKNG-----------QTREHALLAFTLGVKQLIVG--VNKMDSTEPPYSQARFEEITKEVSAYIKKIGYN------------------PASVAFVPISGWHGDNMLEASSNMGWFKGWKIERKEGN----------------------------------ASGTTLLDALDAILPPS-----------------RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKP-GMVVTFAP------------------------ANVTTEVKSVEMHHESLTEATPGDNVG------------------------------FNVKNVSVKDIRRGNVAGDSKNDPPMEAANFNAQVIILNHPGQISQGYAPVLDCHTAHIACKFAELKE---------------------------------------------------------------------------KIDRRSGKKLEDNPKALK---------------------SGDAAIVEMVPGKPMCVESFSTYP------------------PLGRFAVRDMRQTVAVGVIKSVEKKIGGAGKVTKSAQKAAKTK-------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P05303-1", "uniprot_id": "EF1A2_DROME", "id": "P05303-1", "name": "Elongation factor 1-alpha 2", "aln": "--------------MGKEKIHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLK------AERERGITIDIALWKFETSKYYVTIIDAPGHRDFIKN----------------------------------------MITGTSQADCAVLIVAAGTGEFEAG------------------------ISKNG-----------QTREHALLAFTLGVKQLIVG--VNKMDSTEPPYSEARYEEIKKEVSSYIKKIGYN------------------PASVAFVPISGWHGDNMLEPSEKMPWFKGWSVERKEGK----------------------------------AEGKCLIDALDAILPPQ-----------------RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGLLKP-GMVVNFAP------------------------VNLVTEVKSVEMHHEALTEAMPGDNVG------------------------------FNVKNVSVKELRRGYVAGDSKNNPPRGAADFTAQVIVLNHPGQIANGYTPVLDCHTAHIACKFSEIKE---------------------------------------------------------------------------KCDRRTGKTTETEPKAIK---------------------SGDAAIIVLVPSKPLCVESFQEFP------------------PLGRFAVRDMRQTVAVGVIKSVNFKETTSGKVTKAAEKAQKKK-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08736-1", "uniprot_id": "EF1A1_DROME", "id": "P08736-1", "name": "Elongation factor 1-alpha 1", "aln": "--------------MGKEKIHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLK------AERERGITIDIALWKFETAKYYVTIIDAPGHRDFIKN----------------------------------------MITGTSQADCAVLIVAAGTGEFEAG------------------------ISKNG-----------QTREHALLAFTLGVKQLIVG--VNKMDSSEPPYSEARYEEIKKEVSSYIKKIGYN------------------PAAVAFVPISGWHGDNMLEPSTNMPWFKGWKVERKEGN----------------------------------ADGKTLIDALDAILPPA-----------------RPTDKALRLPLQDVYKIGGIGTVPVGRVETGVLKP-GTVVVFAP------------------------ANITTEVKSVEMHHEALQEAVPGDNVG------------------------------FNVKNVSVKELRRGYVAGDSKANPPKGAADFTAQVIVLNHPGQIANGYTPVLDCHTAHIACKFAEIKE---------------------------------------------------------------------------KVDRRSGKTTEENPKFIK---------------------SGDAAIVNLVPSKPLCVEAFQEFP------------------PLGRFAVRDMRQTVAVGVIKAVNFKDASGGKVTKAAEKATKGKK------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P02994-1", "uniprot_id": "EF1A_YEAST", "id": "P02994-1", "name": "Elongation factor 1-alpha", "aln": "--------------MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK------AERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKN----------------------------------------MITGTSQADCAILIIAGGVGEFEAG------------------------ISKDG-----------QTREHALLAFTLGVRQLIVA--VNKMDSVK--WDESRFQEIVKETSNFIKKVGYN------------------PKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGV----------------------------------VKGKTLLEAIDAIEQPS-----------------RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKP-GMVVTFAP------------------------AGVTTEVKSVEMHHEQLEQGVPGDNVG------------------------------FNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDCHTAHIACRFDELLE---------------------------------------------------------------------------KNDRRSGKKLEDHPKFLK---------------------SGDAALVKFVPSKPMCVEAFSEYP------------------PLGRFAVRDMRQTVAVGVIKSVD-KTEKAAKVTKAAQKAAKK--------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A8M1NS15-1", "uniprot_id": "A0A8M1NS15_DANRE", "id": "A0A8M1NS15-1", "name": "Elongation factor 1-alpha", "aln": "--------------MAKERIHINLVIIGHVDGGKSTTTGHLVYKCGGIDHRTIEKYEKAATQMGKSSFKYAWVLDKLK------AERERGITIDISLLKFNTQKYTFTIIDAPGHRDFIKN----------------------------------------MITGTSQADAALLIVSAAKGEFEAG------------------------ISRNG-----------QTREHALLAYTLGVKQLVVC--VNKMDLTEPPFSQKRYDEVVRNVSVFVKKIGFE------------------IGAVPFIPISGWSGENMIVPSQKMQWFKGWKLKRKEGH----------------------------------CHGRTLLEVLDSLHPPV-----------------RNAGKPLRLPLQDVYKIGGVGTVPVGKIETGVLKP-GMVLTFSP------------------------AKLTAEVKSIEMHHQGLQTALPGHNVG------------------------------FNIKNVSVKNLRRGDVAGNAQQDPPSDVSSFIAQIIMLNHPGKIKVGYSPVLDCHTTHVSCRFAELRE---------------------------------------------------------------------------KLDRRSGRKLESWPQYLR---------------------SGDGATVKLVPNKPLCVESFFHYP------------------PLGRFAVRDLKQTVAVGVIKSVEKVDQAK----KTSQKAPVSK-------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O88943-1", "uniprot_id": "KCNQ2_RAT", "id": "O88943-1", "name": "Potassium voltage-gated channel subfamily KQT member 2", "aln": "MVQKSRNGGVYPGTSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSVLSKPRTGGAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMISSQTQTYGASRLIPPLNQLEMLRNLKSKSGLTFRKEPQPEPSPSQKVSLKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLDDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVEDNKSCNCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPTITDKDRTKGPAETELPEDPSMMGRLGKVEKQVLSMEKKLDFLVSIYTQRMGIPPAETEAYFGAKEPEPAPPYHSPEDSRDHADKHGCIIKIVRSTSSTGQRKYAAPPVMPPAECPPSTSWQQSHQRHGTSPVGDHGSLVRIPPPPAHERSLSAYSGGNRASTEFLRLEGTPACRPSEAALRDSDTSISIPSVDHEELERSFSGFSISQSKENLNALASCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFGDVAWAGPRK", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::: ::..* :. ..: . *: . . .: :: . : . . . * . **: ** ** :: * ..: . ::: *. :: .. . :::: .. . : ** :.: * :. : *: :*. *:: : : : : :..:*: * :* *..: : * :. : . . . : * * :. * *.* . : : * * .* * . .: :* . . .:*. ::: . **.:: * :.: ..*: * : : . : : : *: . * *.: : . *: * : :*: * : ** . : :* * .:: :. .. *:** :::: :. : . ::: ", "identical_positions": 52, "similar_positions": 151, "identity": "6.1%" }, { "cls_id": "homologset.agr.SGD:S000006285", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5I0G4-1", "uniprot_id": "GARS_RAT", "id": "Q5I0G4-1", "name": "Glycine--tRNA ligase", "aln": "---------------MPCLLPTLLRA----TRAALLLQSP-RVVAAP--ASQRLLSAPAQP-------------------AASPSSMD--SAEELLAPLRLAVRQQGDFVRKLKEDKAPQVDVDRAVAELKARKRVLEAKELALQPKDDIVDRAKMEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADFMVKDVKNGECFRADHLLKAHLQKLMSDKKCSAEKKSEMESVLAQLDNYGQQELADLFVNYNVKSPTTGNDLSPPVPFNLMFQTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPTEKDHPKFPSVADLYLYLYSAKAQVTG--QSARKMRLGDAVEQGVINNSVLGYFIGRIYLYLTKVGISPDKLRFRQHMENEMAHYACDCWDAESKTSYGWIEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKTVNVVQFEPNKGAVGKAYKKDAKLVLEYLGACDECYITEMELLLSEKGEFTIET-EGKTFQLTKDMVSVKRFQKTLHVEEVVPSVIEPSFGLGRIMYTILEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRNGVSHKVDDSSGSIGRRYARTDEIGVAFGITIDFDTVNKTPHTATLRDRDSMRQIRAEVSELPSVVRDLANGNITWADVEARYPLFEGQETGKKETVEE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CZD3-1", "uniprot_id": "GARS_MOUSE", "id": "Q9CZD3-1", "name": "Glycine--tRNA ligase", "aln": "---------------MPCLLPSLLRA----TRAALPLLSPPRVVAAS--ASQRLLSAPAQP-------------------AASRSSMD--SAEELLAPLRLAVRQQGDFVRKLKEDKAPQVDVDRAVAELKARKRVLEAKELALQPKDDIVDRAKMEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQAWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADFMVKDVKNGECFRADHLLKAHLQKLMSDKKCSAEKKSEMESVLAQLDNYGQQELADLFVNYNVKSPTTGNDLSPPVPFNLMFQTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPTEKDHPKFQSVADLCLYLYSAKAQVTG--QSARKMRLGDAVEQGVINNSVLGYFIGRIYLYLTKVGISPDKLRFRQHMENEMAHYACDCWDAESKTSYGWIEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKTVNVVQFEPNKGAVGKAYKKDAKLVLEYLSACDECYISEMELLLSEKGEFTIET-EGKTFQLTKDMVSVKRFQKTLHVEEVVPSVIEPSFGLGRIMYTILEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRNGVSHKVDDSSGSIGRRYARTDEIGVAFGITIDFDTVNKTPHTATLRDRDSMRQIRAEVSELPNVVRDLANGNITWADVEARYPLFEGQETGKKETVEE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41250-1", "uniprot_id": "GARS_HUMAN", "id": "P41250-1", "name": "Glycine--tRNA ligase", "aln": "---------------MPSPRPVLLRG----ARAALLLLLPPRLLARPSLLLRRSLSAASCPPI-------------SLPAAASRSSMDGAGAEEVLAPLRLAVRQQGDLVRKLKEDKAPQVDVDKAVAELKARKRVLEAKELALQPKDDIVDRAKMEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADFMVKDVKNGECFRADHLLKAHLQKLMSDKKCSVEKKSEMESVLAQLDNYGQQELADLFVNYNVKSPITGNDLSPPVSFNLMFKTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHPKFQNVADLHLYLYSAKAQVSG--QSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGISPDKLRFRQHMENEMAHYACDCWDAESKTSYGWIEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKTVNVVQFEPSKGAIGKAYKKDAKLVMEYLAICDECYITEMEMLLNEKGEFTIET-EGKTFQLTKDMINVKRFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTDEIGVAFGVTIDFDTVNKTPHTATLRDRDSMRQIRAEISELPSIVQDLANGNITWADVEARYPLFEGQETGKKETIEE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A8A7-1", "uniprot_id": "A0AB13A8A7_DANRE", "id": "A0AB13A8A7-1", "name": "Glycine--tRNA ligase", "aln": "-----------MLSVCSATSALLLRTGIFIVRAVPRVRTSPVHLCGSSPTRVLSLSAHLCKKKKR----------SAWLEMTEGQNMDG-SIEEILAPLRLAVKEQGDLVRQLKAENAPDVDVSKAVAELKARKRFLEAKELSLQPKDDIVDRTKMEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNILQVWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADYMVKDVKNGECFRADHLLKAHLQKLMSDKKCPAEKKAEMDNVITQMDNYTQQELADLFVQYNVKSPSTGNDLTPPISFNLMFQTSIGPGGNMQGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPNEKVHFKFSNVADLDIMLYSSKAQTSG--QSAQIMRLGDAVEQGVINNSVLGYFIGRIYLYLVKVGVAKDKLRFRQHMDNEMAHYACDCWDAETKTSYGWIEIVGCADRSCYDLLCHARATKVPLVAEKPLKEPKVVNVVQFEPNKGAIGKAYKKDAKFAMEYLAICDECYITEQEKLLNENGEFTIET-EGKTFKLTKDMVNIKRFQKTLHVEEVVPNVIEPSFGIGRIMYSIFEHTFRIREGDEQRTYFSFPATVAPYKCSVLPLSQNQEFMPFVRELSEALTRNGVSHKVDDSSGSIGRRYARTDEIGVAFGITIDFDTVNKNPHTATLRDRDSMRQIRAEVGELPEIIRDLANGAITWAEVESKYPIFEGQETSKKETVEE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUK8-1", "uniprot_id": "GARS_DROME", "id": "Q9VUK8-1", "name": "Glycine--tRNA ligase", "aln": "MSLQLLKALPHLRSATTAVRTQIARTTWSEHIATKVFFSTTTTKPTPSAPPPPPPTQPQQPAATTSWGTKKQNRKVKLRSAAAEFIMSNPEIEAQLAPLRERVQEQGNLVRDLKAKGAPEIDVKKAVAELKARKKLLEDKELALTPSVVSFDRAKMEDLLKRRFFYDQSFAIYGGITGQYDFGPMGCALKSNILALWRQYFALEEQMLEVDCSILTPEPVLKASGHVERFADLMVKDVKTGECFRLDHLIKQALEKLSKAKDATPALQAECEDIIIKLDGLNKQELAGVLAKYNIKSPLTGNDLTEPIEFNLMFATQIGPTGLVKGFLRPETAQGIFVNFKRLLEFNQGKLPFAVAQIGNSFRNEISPRSGLIRVREFTMAEIEHFCDPVLKDHPKFGNIKSEKLTLYSACNQMDG--KSAAQVQIGEAVASKLVANETLGYYMARIQQFLLAIGIKPECLRFRQHMSNEMAHYACDCWDAEILTSYGWVECVGCADRSAYDLGQHTAATGVRLVAEKRLPAPKTVEVSEIVPNKQALGKTFKKEAKNITDALAKLSLEEITKVEEQLAGDGQYKLTTADGQSHDLGKDTISVKHSTKTVHVEEFIPSVVEPSFGIGRIMYSLLEHSFQCRDGDEQRCYFTLPPLVAPIKCSILPLSNNTDFQPYTQKLSSALTKAELSHKVDDSSGSIGRRYARTDEIAIPYGITVDFDTL-KEPHTVTLRDRNTMKQVRVGLEEVVGVVKDLSTARTTWESVTEQYPLFEQQEASK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06817-1", "uniprot_id": "SYG2_YEAST", "id": "Q06817-1", "name": "Glycine--tRNA ligase 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MPLMSNSERDKLESTLRRRFFYTPSFEIYGGVSGLFDLGPPGCQLQNNLIRLWREHFIMEENMLQVDGPMLTPYDVLKTSGHVDKFTDWMCRNPKTGEYYRADHLIEQTLKKRLLDKDVNPQDMKNMEKILTTIDGFSGPELNLVMQEYNINDPVTNDVLDALTSFNLMFETKIGASGQLKAFLRPETAQGQFLNFNKLLEINQGKIPFASASIGKSFRNEISPRSGLLRVREFLMAEIEHFVDPLNKSHAKFNEVLNEEIPLLSRRLQESGEVQLPVKMTIGEAVNSGMVENETLGYFMARVHQFLLNIGINKDKFRFRQHLKNEMAHYATDCWDGEILTSYGWIECVGCADRAAFDLTVHSKKTGRSLTVKQKLDTPKERTEWVVEVNKKFFGSKFKQKAKLIESVLSKFSQDELIRRHEELEKNGEFTCQV-NGQIVKLDSSLVTIKMKTTLQHIREYIPNVIEPSFGLGRIIYCIFDHCFQVRVDSESRGFFSFPLQIAPIKVFVTTISNNDGFPAILKRISQALRKREIYFKIDDSNTSIGKKYARNDELGTPFGITIDFETI--KDQTVTLRERNSMRQVRGTITDVISTIDKMLHNPDESDWDKSTFGLSPVKI---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :* *:*. *:***** :* ****::* :*:** ** *:.*:: **::* **::*::* .:*** ***:****::*:* * :: *.** :* ***:: *:* *. : :.:: :*. ** :: :**::.* *.: * ***** * **. * : .:******** *:**::***:****:*** *.**:************:***** ******* ** * * ** .: . : * * * * : . : :*:** . :: * .***::.*: :* :*: : :*****:.******* ****.* *****:* ******:.:** *: * *..:: * ** . .* .*. :*:.** . *. . : . . * .*::. . :*: .* .. :.:* . ::.* :*.*:*****:***:* :::* *: * ..*.* :*::* :** * : .:*:* * . :.:*.** : : .*:***. ***::***.**:. .:*:*:**:*: :*.***:*::*:*:* : :: : .: : : : ", "identical_positions": 239, "similar_positions": 181, "identity": "30.88%" }, { "cls_id": "homologset.agr.SGD:S000006286", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P83877-1", "uniprot_id": "TXN4A_MOUSE", "id": "P83877-1", "name": "Thioredoxin-like protein 4A", "aln": "-MSYMLPHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMKMDEVLYSIAEKVKNFAVIYLVDITEVPDFNKMYELYDPCTVMFFFRNKHIMIDLGTGNNNKINWAMEDKQEMVDIIETVYRGARKGRGLVVSPKDYSTKYRY-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P83876-1", "uniprot_id": "TXN4A_HUMAN", "id": "P83876-1", "name": "Thioredoxin-like protein 4A", "aln": "-MSYMLPHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMKMDEVLYSIAEKVKNFAVIYLVDITEVPDFNKMYELYDPCTVMFFFRNKHIMIDLGTGNNNKINWAMEDKQEMVDIIETVYRGARKGRGLVVSPKDYSTKYRY-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q06819-1", "uniprot_id": "DIB1_YEAST", "id": "Q06819-1", "name": "Spliceosomal protein DIB1", "aln": "MASVLLPQLRTGWHVDQAIVTETKRLVVIRFGRKNDRQCMIMDELLSSIAERVRNFAVIYLCDIDEVSDFDEMYELTDPMTVMFFYHNKHMMCDFGTGNNNKLNFIVDDKQEMIDILETIFRGARKNKGLVVSPYDYNHKRVS-------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q5FVI5-1", "uniprot_id": "Q5FVI5_RAT", "id": "Q5FVI5-1", "name": "Thioredoxin-like protein", "aln": "-MSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSADLSKMATIYLVDVDQTPVYTQYFDISYIPSTVFFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVIYRGAMRGKLIVQSPIDPKNIPKYDLLYQDI", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :**:* . .***** : .:::*:***:. * *: :*::* . : : ::*.*** *: :.. : : ::: :.:**:..:*: * *: ::.*: .. **:::*::*.::*** :.: :* ** * . ", "identical_positions": 39, "similar_positions": 59, "identity": "26.0%" }, { "cls_id": "homologset.agr.SGD:S000006289", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A2F0-1", "uniprot_id": "D4A2F0_RAT", "id": "D4A2F0-1", "name": "", "aln": "-----MAAPFPPPP-SPRFVLRGTQSAVNTLHFCPAPGAAENPLLFSGSQNGLVHIWSLQTRRIVATLNGHGGQGVTWLKTLPQGQQLLSQGRDPRLCLWDLAEGRNTVMDSVQ--------------------LDSVGFCKSSILVRGQLC------WMLAVPGKGSDEVQILEMPSKTSVCTLKPEADAKPG------------MPMCLGLWQTNSSLRPLLLAGYEDGSVTLWDVSERK---------VCSQITCHEEPVMGLDFDSQKAKGVSG----------SAGKVLAVWSLDDQQSLQVKKTHELINPGIAEVTLR-------PDHRLFATAGWDHRIRVFHWRT-------IKPLAVLAFHSAPVHCVAFAADGLLAAGSKDQRISVWSLYPCP----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQ15-1", "uniprot_id": "GNB1L_MOUSE", "id": "Q9EQ15-1", "name": "Guanine nucleotide-binding protein subunit beta-like protein 1", "aln": "-----MAALFPPPP-GPRFVLRGTQSAVNTLHFCPPSQAAGNPLLFSGSQNGLVHIWSLQTRRIVTTLNGHGGQGVIWLKTLPQGHQLLSQGRDLRLCLWDLEEGRNTIMDSVQ--------------------LDSVGFCRGSILVRGQQC------WMLAVPGKGSDEVQILEMPSKTSVCTLKPEADARPG------------MPMCLGLWQTNSSLRPLLLAGYEDGSVTLWDISERK---------VCSQITCHEEPVMGLDFDSQKAKGISG----------SAGKVLAVWSLDDQQSLQVKKTHELTNPGIAEVTIR-------PDHKILATAGWDHRIRVFHWRT-------MKPLAVLAFHSAPVYCVAFAADGLLAAGSKDQRISIWSLYPCP----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYB4-1", "uniprot_id": "GNB1L_HUMAN", "id": "Q9BYB4-1", "name": "Guanine nucleotide-binding protein subunit beta-like protein 1", "aln": "-----MTAPCPPPPPDPQFVLRGTQSPVHALHFCEGAQAQGRPLLFSGSQSGLVHIWSLQTRRAVTTLDGHGGQCVTWLQTLPQGRQLLSQGRDLKLCLWDLAEGRSAVVDSVC--------------------LESVGFCRSSILAGGQPR------WTLAVPGRGSDEVQILEMPSKTSVCALKPKADAKLG------------MPMCLRLWQADCSSRPLLLAGYEDGSVVLWDVSEQK---------VCSRIACHEEPVMDLDFDSQKARGISG----------SAGKALAVWSLDWQQALQVRGTHELTNPGIAEVTIR-------PDRKILATAGWDHRIRVFHWRT-------MQPLAVLAFHSAAVQCVAFTADGLLAAGSKDQRISLWSLYPRA----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q06822-1", "uniprot_id": "ASA1_YEAST", "id": "Q06822-1", "name": "ASTRA-associated protein 1", "aln": "MRGFSNEIILKRTLTLSDFTLRYHKRGITALQVIKAPSVSNVPVLLSGDNYGYFVMWDLVTKRPITHIEIEGNSHIIAFWWVETTNVLYILSKDSMLRIFELDSSTQLSIDLVRKLSQANKTDHLQWTKIYEMPINTLNFANFIIEAEVKPTKDNKSYRLVCCHTDDSETIDIYQIIEDSTFKLKRPFNNINFPRFLKQQNFLGISKDSKFGIIMRFAKLNDVIFLGYENGFVVGFKITFDEGLQRDIAELVHVSNDHYPNPILDMCVSGDELYSCSTDDFITKYKIPVNLQLETKYLRDDALLIKCPSSLRVSEPSKVHLPLKNIGHIDKVKDDYLVVSSWSGMTIVYNMRTSEVEQTFVKSKNNLVVSDSSMGDLTNGSGSNTESSSKSHNYKVGAMTCLESFDVQSDGLRLGQLRRIKALAKCNWCLIGYEDGTIKLNKI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . *.** : : :*:. . . *:*:**.: * . :*.* *:* :: :: .*.. : : : . * .:* * :::* .. . :* * ::::.*.. * . : :. .*: ::* :: ..::. :* : . : : .. . ::: ***:* *. :.:: : * : :*::.: ...:: . * : : : * :: : .: :*. ..:.:: . :..:.*. *:: ** ::. *.. .:.: :: :.. :.**.:. .: :: ", "identical_positions": 42, "similar_positions": 138, "identity": "9.48%" }, { "cls_id": "homologset.agr.SGD:S000006290", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62916-1", "uniprot_id": "TF2B_RAT", "id": "P62916-1", "name": "Transcription initiation factor IIB", "aln": "---------MASTSRLDALPRVTCPNHPDAI--LVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSND-KATKDPSRVGDSQNPLLSDGDLSTMIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKALETS------------VDLITTGDFMSRFCSNLCLPKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQSYRLIYPRAPDLFPSDFKFD--TPVDKLPQL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62915-1", "uniprot_id": "TF2B_MOUSE", "id": "P62915-1", "name": "Transcription initiation factor IIB", "aln": "---------MASTSRLDALPRVTCPNHPDAI--LVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSND-KATKDPSRVGDSQNPLLSDGDLSTMIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKALETS------------VDLITTGDFMSRFCSNLCLPKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQSYRLIYPRAPDLFPSDFKFD--TPVDKLPQL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00403-1", "uniprot_id": "TF2B_HUMAN", "id": "Q00403-1", "name": "Transcription initiation factor IIB", "aln": "---------MASTSRLDALPRVTCPNHPDAI--LVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSND-KATKDPSRVGDSQNPLLSDGDLSTMIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKALETS------------VDLITTGDFMSRFCSNLCLPKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQSYRLIYPRAPDLFPTDFKFD--TPVDKLPQL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29052-1", "uniprot_id": "TF2B_DROME", "id": "P29052-1", "name": "Transcription initiation factor IIB", "aln": "---------MASTSRLDNN-KVCCYAHPESP--LIEDYRAGDMICSECGLVVGDRVIDVGSEWRTFSNE-KSGVDPSRVGGPENPLLSGGDLSTIIGPGTGSASFDAFGAPKYQNRRTMSSSDRSLISAFKEISSMADRINLPKTIVDRANNLFKQVHDGKNLKGRSNDAKASACLYIACRQEGVPRTFKEICAVSKISKKEIGRCFKLTLKALETS------------VDLITTADFMCRFCANLDLPNMVQRAATHIAKKAVEMDIVPGRSPISVAAAAIYMASQASEHKRSQKEIGDIAGVADVTIRQSYKLMYPHAAKLFPEDFKFT--TPIDQLPQM---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P29055-1", "uniprot_id": "TF2B_YEAST", "id": "P29055-1", "name": "Transcription initiation factor IIB", "aln": "MMTRESIDKRAGRRGPNLNIVLTCPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTRSEWRTFSNDDHNGDDPSRVGEASNPLLDGNNLSTRIGKGETTDMRFTKELNKAQGKNVMDKKDNEVQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASILIGCRRAEVARTFKEIQSLIHVKTKEFGKTLNIMKNILRGKSEDGFLKIDTDNMSGAQNLTYIPRFCSHLGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAKVGQTLQVTEGTIKSGYKILYEHRDKLVDPQLIANGVVSLDNLPGVEKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : : * ::* : **::*. ****:.*:::*. ********: : ****** ..****...:*** ** * : * *.:..*...*. : ** :*: :.* :**: : * ::: :* :: *.***:: :: :*.: *.**: *.****** :: ::..**:*: ::: : *. . :. . :: ***::* ** * :* : *:*. *:. :.*:***::*..:**: : ::*: *:: **:..*:::* : .*. :: ..:*:** : ", "identical_positions": 95, "similar_positions": 115, "identity": "27.54%" }, { "cls_id": "homologset.agr.SGD:S000006292", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61011-1", "uniprot_id": "SRP54_HUMAN", "id": "P61011-1", "name": "Signal recognition particle subunit SRP54", "aln": "MVLADLGRKITSALR-SLSNATIINEEVLNAMLKEVCTALLEADVNIKLVKQLRENVKSAIDLEEMAS----GLNKRKMIQHAVFKELVKLVDPG---VKAWTPTKGKQNVIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVANAIQPDNIVYVMDASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMGDIEGLIDKVNELK-LDDNEALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQPGRIQRVARGSGVSTRDVQELLTQYTKFAQMVK--------------KMGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPRVLHHMGGMAGLQSMMRQFQQGAAGNMKG----MMGFNNM-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P14576-1", "uniprot_id": "SRP54_MOUSE", "id": "P14576-1", "name": "Signal recognition particle subunit SRP54", "aln": "MVLADLGRKITSALR-SLSNATIINEEVLNAMLKEVCTALLEADVNIKLVKQLRENVKSAIDLEEMAS----GLNKRKMIQHAVFKELVKLVDPG---VKAWTPTKGKQNVIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVSNAIQPDNIVYVMDASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMGDIEGLIDKVNELK-LDDNEALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQPGRIQRVARGSGVSTRDVQELLTQYTKFAQMVK--------------KMGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPRVLHHMGGMAGLQSMMRQFQQGAAGNMKG----MMGFNNM-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYB5-1", "uniprot_id": "SRP54_RAT", "id": "Q6AYB5-1", "name": "Signal recognition particle subunit SRP54", "aln": "MVLADLGRKITSALR-SLSNATIINEEVLNAMLKEVCTALLEADVNIKLVKQLRENVKSAIDLEEMAS----GLNKRKMIQHAVFKELVKLVDPG---VKAWTPTKGKQNVIMFVGLQGSGKTTTCSKLAYFYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVSNAIQPDNIVYVMDASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMGDIEGLIDKVNELK-LDDNEALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQPGRIQRVARGSGVSTRDVQELLTQYTKFAQMVK--------------KMGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPRVLHHMGGMAGLQSMMRQFQQGAAGNMKG----MMGFNNM-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PXC0-1", "uniprot_id": "E9PXC0_MOUSE", "id": "E9PXC0-1", "name": "Signal recognition particle 54 kDa protein", "aln": "MVLADLGRKITSALR-SLSNATIINEEVLNAMLKEVCTALLEADVNIKLVKQLRENVKSAIDLEEMAS----GLNKRKMIQHAVFKELVKLVDPG---VKAWTPTKGKQNVIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVSNAIQPDNIVYVMDASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMGDIEGLIDKVNELK-LDDNKALIEKWKHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKHPGRIQRVARGSGVSTRDIQELLTQYTKFAQMVK--------------KMGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPRVLHHMGGMAGLQSMMRQFQQGAAGNMKG----MMGFNNM-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7ZVN5-1", "uniprot_id": "SRP54_DANRE", "id": "Q7ZVN5-1", "name": "Signal recognition particle subunit SRP54", "aln": "MVLADLGRKITSALR-SLSNATIINEEVLNAMLKEVCAALLEADVNIKLVKQLRENVKAAIDLEEMAS----GLNKRRMIQHAVFKELVKLVDPG---VKAWTPTKGKNNVIMFVGLQGSGKTTTCSKLAYYFQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIAAEGVEKFKSENFEIIIVDTSGRHKQEDSLFEEMLQVSNAVQPDNIVYVMDASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMGDIEGLIDKVNELK-LDDNEELIDKLKHGQFTLRDMYEQFQNIMKMGPFGQIMGMIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDNKDGAKLFSKQPNRIQRVARGSGVATRDVQELLTQYTKFAQMVK--------------KMGGIKGLFKGGDMSKNVNPSQMAKLNQQMAKMMDPRVLHHMGGMAGLQSMMRQFQQGAAGNMKG----MMGFNNM-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3D9-1", "uniprot_id": "Q9V3D9_DROME", "id": "Q9V3D9-1", "name": "Signal recognition particle 54 kDa protein", "aln": "MVLADLGRKITTALH-SLSKATVINEEALNSMLKEICAALLEADVNIRLVKQLRENVRAVIDFDEMAG----GLNKRRMIQSAVFKELVKLVDPG---VKPYQPIKGKANVVMFVGLQGSGKTTTCTKLAYHYQKRNWKSCLVCADTFRAGAYDQVKQNATKARIPFYGSYTEIDPVVIAQDGVDMFKREGFEMIIVDTSGRHKQEESLFEEMLAVSNAVSPDNIIFVMDATIGQACEAQAKAFKDKVDIGSVIITKLDGHAKGGGALSAVAATQSPIIFIGTGEHIDDLEPFKTKPFVSKLLGMGDIEGLIDKVNELK-LDGNDELLEKIKHGHFTIRDMYEQFQNIMKMGPFSQFMNMIPGFSQDFMTKGGEQESMARVKRMMTMMDSMSDNELDNRDGAKLFSKQPNRCVRVAQGAGVMEREVKELIAHYTKFSAVVK--------------KMGGVKGLFKQGDMTKNVNPTQMAKLNQQIAKMIDPRMLQQMGGVGGIQNMMRQLQQGAAGGLGGLGNLMSGFGGK-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20424-1", "uniprot_id": "SRP54_YEAST", "id": "P20424-1", "name": "Signal recognition particle subunit SRP54", "aln": "MVLADLGKRINSAVNNAISNTQDDFTTSVDVMLKGIVTALLESDVNIALVSKLRNNIRSQLLSENRSEKSTTNAQTKKLIQKTVFDELCKLVTCEGSEEKAFVPKKRKTNIIMFVGLQGSGKTTSCTKLAVYYSKRGFKVGLVCADTFRAGAFDQLKQNAIRARIPFYGSYTETDPAKVAEEGINKFKKEKFDIIIVDTSGRHHQEEELFQEMIEISNVIKPNQTIMVLDASIGQAAEQQSKAFKESSDFGAIILTKMDGHARGGGAISAVAATNTPIIFIGTGEHIHDLEKFSPKSFISKLLGIGDIESLFEQLQTVSNKEDAKATMENIQKGKFTLLDFKKQMQTIMKMGPLSNIAQMIPGMS-NMMNQVGEEETSQKMKKMVYVLDSMTKEELES--DGRMFIEEPTRMVRVAKGSGTSVFEVEMILMQQQMMARMAQTATQQQPGAPGANARMPGMPNMPGMPNMPGMPNMPGMPKVTPQMMQQAQQKLKQNPG---LMQNMMNMFGGGMGGGMGG---GMPDMNEMMKMMQDPQMQQMAKQFGMG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******::*.:*:. ::*:: :: *** : :****:**** **.:**:*::: : :: : . :.:::** :**.** *** *.: * * * *::************:*:*** .:.::.:* *:*********:**:**** :*********** **. :* :*:: ** * *::*********:**:.**:**: ::*.:.*:: : *:**:****.* *:****:. *..::*:**:****:****:******::***********.*:* *..:.*:*****:****.*::::: :. :. . ::: ::*:**: *: :*:*.******:.:: ****:. ::*.: .*:*: ::*::: ::***..:**:. ..::* :.* * ***:*:*. ::: :: : :: :.: :* *: .: :*. . . *.*:. *: : : :: :: * :*.**. : * .*.: * * .:. ", "identical_positions": 212, "similar_positions": 189, "identity": "38.55%" }, { "cls_id": "homologset.agr.SGD:S000006295", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V9L1-1", "uniprot_id": "G3V9L1_RAT", "id": "G3V9L1-1", "name": "", "aln": "MTSLNGRHAEKTIDMPKPS-----APKVHVQRSVSRDTIAIHFSASGEEEEEEEEELR--GYLEEGLD--DQSIVTGLEAKEDLYLEPQGGHDPAGPAVATAPADGLSVSETPAILPVSENTVKLLEPPAPAVQVLSPVPLALSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPVLSSSASSSALSSAKPFMSLVKSLSTEVEPKES------PHPPRHRHLMKTLVKSLSTDTSRQESD-SVSYKAPDSKLNLHLFKQFTQPRNTGG--DSKTAPSSPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIMGEESG--------------SHRPKALSSSASELSNLSSLNGHLESNN-YSIKEEEGDSEGDDYGSDSNTPRTDHLKPSEDASKEGEPKGSQASSLK-----TSSLVLEKCSLSALVSKEDEEFCELYTEDFELEAEGEGR-LDKPPDIPLKPEVPASEGVALDSEDEED------------------PGSEHPELPVKTLSFFILCVYAYLILPLPYYMSGLFLG--------LGLGFMTAVCMIWFFT-PPSAHKYHRSHKALRHRNSR--SLDIREPEILKGWMNEIYSYDPETYHATLTHSVFVRLEGGTLRLSKPNKNISRRASYNET---KPEVTYISQKIYDLSDSKIYLVPKSLARKRIWNKKYPICIELGRQDDFMSKAQTDK---EAGEEKLPPERELASEDLKKPPQPQEG------------------------------TKSSQRDPILYLFGRTGREKEEWFRRFTLASK--------------------LKSDLKKSSGVSGSKSGLLPAHSRHSSPSGHLSHSRSSSKGS------MEEMMP-QPKQKELLGGVRQKMLLDYSVYMGRCVPQDGQSPHRSPVQSAESSPTAGKKLPEAPPSEEEEQE---------------------AWVNALLGRIFWDFLGEKYWSDVVSKKIQMKLSKIKLPYFMNELTLTELDMGVAVPKILQAFKPYVDHQGLWIDLEMSYNGSFLMTLETKMNLTKLGKEPLV-----EALKVGEIGKEGCRPRAYCLADS-----DEESSSAGSSEEDDPPEPSAGDKQPLPGAEGYVGG-HRTSKIMRFVDKITKSKYFQKATETEFIKKKMEEVSNTPLLLTVEVQECRGTLAVNIPPPPTDR-MWYGFRKPPYVELKARPKLGEREVTLVHVTEWIEKKLEQELQKVFVMPNMDDVYIPIMHSAMDPRSTSCLLKEP----PVEASD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZPJ0-1", "uniprot_id": "TEX2_MOUSE", "id": "Q6ZPJ0-1", "name": "Testis-expressed protein 2", "aln": "MTSLNGRHAEKTIDMPKPS-----APKVHVQRSVSRDTIAIHFSASGEEEEEEEEEFR--GYLEEGLD--DQSIVTGLEAKEDLYLESQGGHDPAGP-VSTAPADGLSVSESPAILPVSENTVKLLESPAPALQVLSPVPLALSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPVLSSSASSSALSSAKPFMSLVKSLSTEVEPKES------PHPPRHRHLMKTLVKSLSTDTSRQESD-TVSYKPPDSKLNLHLFKQFTQPRNTGG--DSKTAPSSPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIIGEESG--------------SHRPKALSASASELSSLSGLNGHLESNN-YSIKEEEGDSEGEGYGSDSNTSRSDHLKPTEDASKEVEPKGSQASSLKDLGLKTSSLVLEKCSLSALVSKEDEEFCELYTEDFELETEGEGR-LDKTLDLPLKPEVLASDGVALESEDEED------------------SATEHQELPVKTLGFFIMCVYAYLILPLPYYMSGLFLG--------VGLGFMTAVCMIWFFT-PPSAHKHHKSLKALRHQSTR--SLDIKEPEILKGWMNEIYNYDPETYHATLTHSVFVRLEGGTLRLSKPNKNISRRASYNET---KPEVTYISQKIYDLSDSKIYLVPKSLARKRIWNKKYPICIELGRQDDFMSKAQSDK---EATEEKPPPEKELPSEDLKKPPQPQEG------------------------------TKSSQRDPILYLFGRTGREKEEWFRRFILASR--------------------LKSELRKPAGVSGSKSGLLPAHSRHSSPSGHLSHSRSSSKGS------VEEMMS-QPKQKELVGSVRQKMLLDYSVYMGRCVPQDNRSPHRSPVQSAESSPTASKKLPEAPPSEEEEQE---------------------AWVNALLGRIFWDFLGEKYWSDVVSKKIQMKLSKIKLPYFMNELTLTELDMGVAVPKILQAFKPYVDHQGLWIDLEMSYNGSFLMTLETKMNLTKLGKEPLV-----EALKVGEIGKEGCRPRAYCLADS-----DEESSSAGSSEEDDPPEPTAGDKQPLPGAEGYVGG-HRTSKIMRFVDKITKSKYFQKATETEFIKKKIEEVSNTPLLLTVEVQECRGTLAVNIPPPPTDR-IWYGFRKPPYVELKARPKLGEREVTLVHVTEWIEKKLEQELQKVFVMPNMDDVYIPIMHSAMDPRSTSCLLKEP----PVETSDQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IWB9-1", "uniprot_id": "TEX2_HUMAN", "id": "Q8IWB9-1", "name": "Testis-expressed protein 2", "aln": "MTSLYGRHAEKTTDMPKPS-----APKVHVQRSVSRDTIAIHFSASGEEEEEEEEEFR--EYFEEGLD--DQSIVTGLEAKEDLYLEPQVGHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKES------PHPARHRHLMKTLVKSLSTDTSRQESD-TVSYKPPDSKLNLHLFKQFTQPRNTGG--DSKTAPSSPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIIGEESG--------------SHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDGYGSDSNIPRSDHPKSTGEPTREIELKSSQGSSLKDLGLKTSSLVLEKCSLSALVSKEDEEFCELYTEDFDLETEGESK-VDKLSDIPLKPEVLAEDGVVLDSEDEVD------------------SAVQHPELPVKTLGFFIMCVYVYLILPLPHYVSGLFLG--------IGLGFMTAVCVIWFFT-PPSAHKYHKLHKNLRHWNTR--SLDIKEPEILKGWMNEIYNYDPETYHATLTHSVFVRLEGGTLRLSKPNKNISRRASYNEP---KPEVTYISQKIYDLSDSKIYLVPKTLARKRIWNKKYPICIELGQQDDFMSKAQTDK---ETSEEKPPAE---GSEDPKKPPRPQEG------------------------------TRSSQRDQILYLFGRTGREKEEWFRRFILASK--------------------LKSEIKKSSGVSGGKPGLLPAHSRHNSPSGHLTHSRSSSKGS------VEEIMS-QPKQKELAGSVRQKMLLDYSVYMGRCVPQESRSPQRSPLQSAESSPTAGKKLPEVPPSEEEEQE---------------------AWVNALLGRIFWDFLGEKYWSDLVSKKIQMKLSKIKLPYFMNELTLTELDMGVAVPKILQAFKPYVDHQGLWIDLEMSYNGSFLMTLETKMNLTKLGKEPLV-----EALKVGEIGKEGCRPRAFCLADS-----DEESSSAGSSEEDDAPEPSGGDKQLLPGAEGYVGG-HRTSKIMRFVDKITKSKYFQKATETEFIKKKIEEVSNTPLLLTVEVQECRGTLAVNIPPPPTDR-VWYGFRKPPHVELKARPKLGEREVTLVHVTDWIEKKLEQEFQKVFVMPNMDDVYITIMHSAMDPRSTSCLLKDP----PVEAADQP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5J4-1", "uniprot_id": "A0ACD6B5J4_DANRE", "id": "A0ACD6B5J4-1", "name": "", "aln": "MTSKGGSHEDTLSPPSSSSSRSSAARKVQVQRSLSRDTITIHFSAKGNEEEEEEEELYRLAVSPSGLETEDQSIVTAQEASEELLSEGLG----------ADMVTGMSCQTQSSALAIQHP--------------------SVSLGCTATSNLAS---FSWPSEQR--STPPLPSTHS---ASSSSSPAKALPSKPFLSLVKSLSSEVESREAPTVA--PQSVRHRHLMKTLVKSLSTDTARPEQEPSSTPRPPDSRLNLHLFKPFTQTRVPGGSGDSKTAPSSPLTSP-DSRSFFKVQEVEARIEDTKRRLSEVMCEPLQLLSKIIGEEPGGVSANSSSSTAAGVSYRSRNLSSSASELSNLSALNGHSESNNNYCIKEEE-DLENE--------------SPVESATVELPLHRS------------PSLGLDRCFMSTLARQEDEDFCELYTEDFEFCTDMELDGEETHISLVQRGSTAGCSEEPTEGGEEEE------------------EEDEPPGVPHNGLILLISIVYGYFVLPLPSYVCWVLMG--------VAAGFMLAILVVWLSARQKTSWGRHGSLSRRHQWNRV--PLDIKEPAIYKGWMNEICSYDPETYHATLTHSVYVRLEGSVLRLSKPNRNIPRRATFSEL---KPDVTYVSQKIYDLTNSKVYLVPNNLARKRVWNKKYPICIELAKQDDFLAKAQGEKT--EVMEEKTLTAG-----DKAEIVSTSEE------------------------------PKRLHTEPVLYLFGRTGRDKEEWFRRMLFASK--------------------LKSEAKKPSGL----------------PTSCLSHSRSSSRGS------LDEVLQSHPKQKDLGASVKQK-VLEYNVYMAKYVSQSVGSPTTSPVQSAGSSPGTTKKFPES-CEQSAETE---------------------AWINALLGRMFWDFLREKYWADVVSKKIQKKLSKIRLPYFMNELTLTELDMGISIPKILSSSKPSVDHKGLWFDLEISYNGSFLMTLETKMNLTRLGKE---------GEGLGEQGKEGSRPRTYFLADS-----DEESSSAGSSDEEDTVEVP-----EIPGVEGFVGG-HKPSKIMRFVDKIAKSKYFQKATETEFIKKKIEEVSNTPLLLTVEVQECQGTLAVNIPPPPTDR-IWYGFRRPPRLELKARPKLGEREVTFAHVTDWIEKKLDQEFQKIFVMPNMDDVWLPIMHSAMDTRSNASALRDEETLDPKESLEDM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PHU7-1", "uniprot_id": "M9PHU7_DROME", "id": "M9PHU7-1", "name": "SMP-LTD domain-containing protein", "aln": "MDSLKLPKANSATSSASGS---------NSNLSGSTSASASAATSPTSSGTAVGGILSGAPKSPPGLG-SSTPISVRFNANEESLDDILQSFHHSKHSPSGGASGGGDASPTSNLLGMKNNGLGLVVGN------------CDSLSSSPSQPQMHAGSASLFGNDEVSLRNNFMQAGGFFNRKRSGSIEGVSPTSSGPSIISTLSTASAAGGGGSSVGGAVAAGDSNSSGGTWRLIKGKVTQTIEEIKSSKLPPTAAIPIIVADPPSTGWSNDPDSDTECLTVNTSISEELPLDLEHKQNSDSDVEAELLQHDSISLGSGDVPTVAATGHSERSRLRRG------LAHIRSKVKAKQQAAPAMNKKDVSPSGSTVPATSVRTGFLRRRNVVEAGSEPSTSQQAEIAIASGKVKKRGILLARKDVEIESGVEVLEDMIPSTAVHIDHSKDVANKRAEEVTDAGADADSRASLTLPVAPGFSTLASSYVEKESGVRDTRSRISFFSNLSMLSVSQWREKHQGATAFALPVLLSVLLILLMILPVPDFLRGVFATLLFFTVMDCCGGHLRALLEDFMLTTHPERVAFAIPNYKFMPICEIPAVEEHKTIKTYAGWMNEINSYDPNTFSFSLTRAVYVRLDGSILKMSGTNARIPKRRMWNEPPIDRHKIPFTDHRSYDLRDCRIELLPLGLANKRFFNRKYPIQLIIKSNRDVPDEQSSVESQSEATVKTDAKEAKAASSSGTTPPGGEEEKLVDFAGTVMQADLQQLRNTVNPDKELNDITVPCGDEVRLLLFSRCDREKEDWYRRFTNASRGLVHEQDLQVPMARFVEDSDLQAAAARQALLLVTGMGKAGVKSEDEISAGKGNDETDQQTPDGQFETITEEDLLDTPKEESFDGMIMSANVARNSPDYVRFMAVYQKACNQSTIPVTRSSVGTMRTTDRRPRKSRRAKRQEDELWKGIDQSLFLGPSGSIVWANVLLGRCLYSWLHDAMLHEKLKEVLQKKLNSIKLPSFMEEVIITNIYLGESPLLCHRVSQPMLDERGVWIDADVTYEGLAHITVTTKLNLLRIRSKTKSPMATDNVPTTSMLPEQSQDLRSLSEVNSENVIYDSDAESSGGSSTESESPPPGNAPENAAGTEFFQNSPGNARRIFKIVDRIAASNLFQYATELPYVQRAMENMN-ANITLRVDLKGLVARGTLNVPPPPSDR-VWVSFRGPPRLWISTKPQVGDKSVDWSIVTNVIESKLCEAVNKFLVYPNMVDFSIPFLSNPNFDEDQGNAAN--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06833-1", "uniprot_id": "NVJ2_YEAST", "id": "Q06833-1", "name": "Nucleus-vacuole junction protein 2", "aln": "MASLKVFLAVYLLGG-------------ITFLPLVLFTLYKIHLLYSNLKSASKKELDHDTADEIDEKTRLLARDIDPEFKARKLEEQLGVKVFNKGWITVTKQYYYHSSEVAVILKNSNN-------------------------NKDSDTALQEQILQRTDLKKKQRFFAVLRHGNLFLYKDDSQNANLVHAISLQNRFITIWPRFDELGKE-----ELPDASLFTKRTCIAIFKNDLVSIDSK--------NHNVILPHFDPLTSAESNNGDISTNDTTHEYQSQFHSSNQFFLYFDNNMDKEDWYYQLINASKNSNSLSTGLLDPNVS--------------------ANAAHLKTKDMLQLIQDINSTENQLTTKWLNALLGR---------------------------------------LFLSLQQTDTLNKFIHEKICKKLNKIKTPGFLDDLVVEKVDVGDSAPLFTSPELLELSPEG------------------------------------------------------------------------------------------------------------------------------------------STKIAIDVQYRGNLTIIIATKASINLGSRFKQR----EVSLQLSIKIKEFSGPLLFLIKPPPSNRIWYAFRTEPIMDFEIEPIVSSSKLSYN---------------------------------------------------------------VVTNAIKSKFAEAVKES--------LVVP-------------------------------------------------------------------FMDDIVFYPTPNEVYRGGIWEEQDPEAAARARTAAAASDMNNTSAKEHLEALQEGGMKTQSRIKKALRPERK-------------------------------------KENLKDLVDASGVATKTTTQT--TVTTATNDDVSSSENSTKSRKYFKNSIKKIGRWYKDNVGNS------------------------------------SDTEDMDEIDVQDK------KNDDSADERESDNP---------------------------------ILTSNPKMISNRRPVPRRPSQPLN----TLSPKLEGRKEKDTENFPVPPSASNMNASKMFANKENRKFSVSSNDSQNSLKNGDPHVKASKLESSQAFVKKTSQNRFNDGFFKQDLEFEEQREPKL--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * . : . : . . : . : . . * .. . : . . .. . . ... : . . . :: . . :. . .. : : . : . .:: . . . . .: : : * : . . .: : . .: : ... . .: . : . :.. : : . : . . : . :: *: *. : .: * :.: . : :: . : *: :.: : : : : : . . : : *.. ::. . :: : . :: . : . . : . :. . . . : :. . .. : : :: . : :.. * * . :: . .: :. .: .*:. . :. * *: :.. :: : :. * .:: : *.* **: : . . . . .: . :: . : : .. .. . :: . .. ", "identical_positions": 19, "similar_positions": 204, "identity": "1.47%" }, { "cls_id": "homologset.agr.SGD:S000006298", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7RTV0-1", "uniprot_id": "PHF5A_HUMAN", "id": "Q7RTV0-1", "name": "PHD finger-like domain-containing protein 5A", "aln": "MAKHHPDLIFCRKQAGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVICG-GPGVSDAYYCKECTIQEKDRDGCPKIVNLGSSKTDLFYERKKYGFKKR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P83871-1", "uniprot_id": "PHF5A_RAT", "id": "P83871-1", "name": "PHD finger-like domain-containing protein 5A", "aln": "MAKHHPDLIFCRKQAGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVICG-GPGVSDAYYCKECTIQEKDRDGCPKIVNLGSSKTDLFYERKKYGFKKR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P83870-1", "uniprot_id": "PHF5A_MOUSE", "id": "P83870-1", "name": "PHD finger-like domain-containing protein 5A", "aln": "MAKHHPDLIFCRKQAGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVICG-GPGVSDAYYCKECTIQEKDRDGCPKIVNLGSSKTDLFYERKKYGFKKR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VMC8-1", "uniprot_id": "PHF5A_DROME", "id": "Q9VMC8-1", "name": "PHD finger-like domain-containing protein 5A", "aln": "MAKHHPDLIFCRKQPGVAIGRLCEKDDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVICG-GPGVSDAYYCKSCTIQEKDRDGCPKIVNLGSSKTDLFYERKKYGFKQNY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06835-1", "uniprot_id": "RDS3_YEAST", "id": "Q06835-1", "name": "Pre-mRNA-splicing factor RDS3", "aln": "MSRHQFDLIMCLKQPGVQTGLLCEKCDGKCPICDSYVRPKRKVRVCENCSFGKQAKNCIICNLNVGVNDAFYCWECCRLGKDKDGCPRILNLGSNRLDRHFEKK----KKV-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::*: ***:* **.** * **** **** ******** **:*::*.:*. .*:**. . **.**:** .* **:****:*:****.: * .:*:* *: ", "identical_positions": 57, "similar_positions": 27, "identity": "50.89%" }, { "cls_id": "homologset.agr.SGD:S000006302", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJZ0-1", "uniprot_id": "D3ZJZ0_RAT", "id": "D3ZJZ0-1", "name": "Transmembrane protein 205", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEGEDPGSLIKVIHLLVLSGVWGMQMWVTFASGFLLFRSLPRHTFGLVQSKLFPVYFHVSLGCAFINLCILAPQRAWINLTLWEISQLTLLLLSLTLATINARWLEARTTATMWALQSIEKERGLGTEVPGSLQGPDPYRQLREKDPKYSALRQKFFYYHGLSSLCNLG---CLLSNGLCLVGLALGLRSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XE8-1", "uniprot_id": "TM205_MOUSE", "id": "Q91XE8-1", "name": "Transmembrane protein 205", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKGEDPGSLIKVIHLLVLSGAWGMQVWVTFISGFLLFRSLPRHTFGLVQSKVFPVYFHVSLGCAFINLCILAPQRAWIHLTLWEVSQLSLLLLSLTLATINARWLEARTTAVMRALQSIEKERGLGTEVPGNFQGPDPYRQLRDKDPKYSALRRKFYHYHGLSSLCNLG---CLLSNGLCLVGLALGLRSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UW68-1", "uniprot_id": "TM205_HUMAN", "id": "Q6UW68-1", "name": "Transmembrane protein 205", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEGGNLGGLIKMVHLLVLSGAWGMQMWVTFVSGFLLFRSLPRHTFGLVQSKLFPFYFHISMGCAFINLCILASQHAWAQLTFWEASQLYLLFLSLTLATVNARWLEPRTTAAMWALQTVEKERGLGGEVPGSHQGPDPYRQLREKDPKYSALRQNFFRYHGLSSLCNLG---CVLSNGLCLAGLALEIRSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L2F6-1", "uniprot_id": "TM205_DANRE", "id": "A1L2F6-1", "name": "Transmembrane protein 205", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATEGDPTDFVKVLHLLVISFTWGMQVWVSFIAGFVLISQVSMHTFGLVQSKLFPVYFYCLLGGNAVSLAVYAVYHPRELLDWHEGIQMSLFFVAVIMAGLNAQWFGPSATENMLVMQEIEKEHGLGNQV-GMSSNREGYTKLREQDPKYKEHRSTFYRYHGLSNLCNLI---GFFCITVNLIYLALNLGTI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRE4-1", "uniprot_id": "Q9VRE4_DROME", "id": "Q9VRE4-1", "name": "TMEM205-like domain-containing protein", "aln": "MCHNSGIVEKNNEQQIERYMACGMPSKAVKSVKYTLKKREKKEQQRRDLEKDLHREQQFLEELELSSSASDSSSSSSSSSVTGSDSEDSGVTETVLKSSPSADMTTSPKVISPAPTPRSDLLRFCPRFRKLQQEQQQQMLKEMELQEEEPLATSTPAAALKAQQQRKLSSMEPSMDDALAIGTQMTRQVSERITCLVAKLQASRLYTILTRTTQPAHLIAVCILAFVLMTVGRDLIDPTTTVATAEAAASATAASTRTATGGVMAALVFLGAFATHFGSQIWMTFVSGLSLYFSLPRHVFGQCQQILFPRYFALNAMLSLTMLVVYAKYFLSG-WTTSAGIQMGSLALAAGIEVVVRLYLVPPMLQLMHEKYRIEDAIGSGQEVGSLVQG------DLVDCPHYQRIHKGFRRIHMTIAIGNMT---VMLTTCLQLYFLASKIRLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06089-1", "uniprot_id": "YP098_YEAST", "id": "Q06089-1", "name": "Uncharacterized mitochondrial outer membrane protein YPR098C", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCLVKTTAHLLFYSFVFGGTTFYSYVASPIAFKVLEKDQFSALQNKIFPYFFQMQAASPVILALTAPIALTTG--------PLSSLVVASVSGLTNLFWLLP------WTHKVKEQRKNIAKKYTG-----------SELEAKDAILRKEFGKSHGLSLLFNLSNVCGMLAYGVCLSGGLLRKIPK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .* : :* : :: :. : . *. *. :** :* . : : :: :: . *. . . : . .: : * * : *: .: : * ", "identical_positions": 12, "similar_positions": 36, "identity": "2.69%" }, { "cls_id": "homologset.agr.SGD:S000006304", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZXF8-1", "uniprot_id": "D3ZXF8_RAT", "id": "D3ZXF8-1", "name": "Large ribosomal subunit protein mL43", "aln": "--MTARGTPSRFLTSVLHNGLGRYVQQLQRLSLTLSRDAPSSRGAREFVEREVTDFARRNPGVVIYLNPRPCAVPRIVAEYLNGAVREENVNSKSVEEITSLVQKLADQSG-LDVIRIRKP---FHTDNPSIQGQWHPFTNKRTTFHGLRPRELQDSAPASI-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N983-1", "uniprot_id": "RM43_HUMAN", "id": "Q8N983-1", "name": "Large ribosomal subunit protein mL43", "aln": "--MTARGTPSRFLASVLHNGLGRYVQQLQRLSFSVSRDGASSRGAREFVEREVIDFARRNPGVVIYVNSRPCCVPRVVAEYLNGAVREESIHCKSVEEISTLVQKLADQSG-LDVIRIRKP---FHTDNPSIQGQWHPFTNKPTTFRGLRPREVQDPAPAQDTGLRLSAVAPQILLPGWPDPPDLPTVDPISSSLTSAPAPMLSAVSCLPIVPALTTVCSA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99N89-1", "uniprot_id": "RM43_MOUSE", "id": "Q99N89-1", "name": "Large ribosomal subunit protein mL43", "aln": "--MTGRGTSSRFLTSVLHNGLGRYVQQLQRLSLSLSRDAPSSRGAREFVEREVTDFARRNPGVVVYVNPRPCAMPRIVAEYLNGAVREENVNSKSVEEIKSLVQKLADQSG-LDVIRIRKP---FHTDNPSIQGQWTPSPTNGLPSTGCGP---------ENSGILLQLRCKHSKEPGALDRER----DRIGSSFGFQAQAE-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9W1L1-1", "uniprot_id": "Q9W1L1_DROME", "id": "Q9W1L1-1", "name": "Large ribosomal subunit protein mL43", "aln": "MSNSHLFLKSGFPRAPLQNGLGRYVCQLQRITLKFCKNNGSSRGMRDFIENHLLDFAKENPGIVVYVKPRRHRTPVLVGEYLNGEREWMSCRNSTQEEISKWIDLLKTQNGSSSSLRLRKM---WHTEVPSIQGPWTPFLLRSPDAQGQAYP------SAEASKPLDTPQTATEKLIELFRQQQLEAGEEAHDVLNKKRAE--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06090-1", "uniprot_id": "RM51_YEAST", "id": "Q06090-1", "name": "Large ribosomal subunit protein mL43", "aln": "-----MVVKAIARNSIGRNGVGAFVFPCRKITLQFCNWGGSSEGMRKFLTSKRLDKWGQEFPWIQFEVMRKSGHPLLRAEYTNGREKVICVRNLNIDNVENKLKLLKDSDG--DILRRRTKNDNVESLNSSVRGIWSPLHAAKRHRI--------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :**:* :* ::::: ... **.* *.*: . * .: : : * * : .** ** . . . ::: . :. * ..* . :* *. .: .*::* * * ", "identical_positions": 24, "similar_positions": 42, "identity": "10.86%" }, { "cls_id": "homologset.agr.SGD:S000006306", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62913-1", "uniprot_id": "RL11_HUMAN", "id": "P62913-1", "name": "Large ribosomal subunit protein uL5", "aln": "MAQ-----DQGEKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKYDGIILPGK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62914-1", "uniprot_id": "RL11_RAT", "id": "P62914-1", "name": "Large ribosomal subunit protein uL5", "aln": "MAQ-----DQGEKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKYDGIILPGK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CXW4-1", "uniprot_id": "RL11_MOUSE", "id": "Q9CXW4-1", "name": "Large ribosomal subunit protein uL5", "aln": "MAQ-----DQGEKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKYDGIILPGK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46222-1", "uniprot_id": "RL11_DROME", "id": "P46222-1", "name": "Large ribosomal subunit protein uL5", "aln": "MAAVTKKIKRDPAKNPMRDLHIRKLCLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILERGLKVREYELRRENFSSTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGYNVNHRKRKSGTVGFQHRLTKEDAMKWFQQKYDGIILNTKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0C0W9-1", "uniprot_id": "RL11A_YEAST", "id": "P0C0W9-1", "name": "Large ribosomal subunit protein uL5A", "aln": "MSA--------KAQNPMRDLKIEKLVLNISVGESGDRLTRASKVLEQLSGQTPVQSKARYTVRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLRDRNFSATGNFGFGIDEHIDLGIKYDPSIGIFGMDFYVVMNRPGARVTRRKRCKGTVGNSHKTTKEDTVSWFKQKYDADVLDK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :****:*:*.** ***.***********:******:** ** ********:************ ****.*******:****:**:** .*** ********:***************:*:*****:.*** : :** .* :* .*: :**::: **:****. :* ", "identical_positions": 121, "similar_positions": 32, "identity": "65.76%" }, { "cls_id": "homologset.agr.SGD:S000006307", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28063-1", "uniprot_id": "PSB8_MOUSE", "id": "P28063-1", "name": "Proteasome subunit beta type-8", "aln": "-MALLDLCGAARGQRPEWAA-LDAGSGGRSDPGHYSFSAQAPELALPRGMQPTAFLRSFGGD-QERNVQIEMAHGTTTLAFKFQHGVIVAVDSRATAGSYISSLRMNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMLQYRGMGLSMGSMICGWDKK-GPGLYYVDDNGTRLSGQMFSTGSGNTYAYGVMDSGYRQDLSPEEAYDLGRRAIAYATHRDNYSGGVVNMYHMKEDGWVKVESSDVSDLLYKYGEAAL-------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28064-1", "uniprot_id": "PSB8_RAT", "id": "P28064-1", "name": "Proteasome subunit beta type-8", "aln": "-MALLDLCGAPRGQRPEWAA-VDAGSGLRSDPGHYSFSVQAPELALPRGMQPTEFLRSFGDD-QERKVQIEMAHGTTTLAFKFQHGVIVAVDSRASAGSYIATIRVNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMLQYRGMGLSMGSMICGWDKK-GPGLYYVDDNGTRLSGQMFSTGSGNTYAYGVMDSGYRQDLSPEEAYDLARRAIVYATHRDSYSGGVVNMYHMKKDGWVKVESTDVSDLLHKYREATL-------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28062-1", "uniprot_id": "PSB8_HUMAN", "id": "P28062-1", "name": "Proteasome subunit beta type-8", "aln": "-MALLDVCGAPRGQRPESAL-PVAGSGRRSDPGHYSFSMRSPELALPRGMQPTEFFQSLGGD-GERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKK-GPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ-------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O55234-1", "uniprot_id": "PSB5_MOUSE", "id": "O55234-1", "name": "Proteasome subunit beta type-5", "aln": "-MALASVLQRP---MPVNQH-GFFGLGGGADLLDLGPGSPGDGLSLAA--------PSWGVP-EEP--RIEMLHGTTTLAFKFLHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKR-GPGLYYVDSEGNRISGTAFSVGSGSVYAYGVMDRGYSYDLKVEEAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHDKYSSVSVP------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28075-1", "uniprot_id": "PSB5_RAT", "id": "P28075-1", "name": "Proteasome subunit beta type-5", "aln": "-MALASVLQRP---MPVNQH-GFFGLGGRADLLDLGPGSPGDGLSLAA--------PSWGVP-EEP--RIEMLHGTTTLAFKFQHGVIVAADSRATAGPYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKR-GPGLYYVDSEGNRISGTAFSVGSGSVYAFGVMDRGYSYDLQVEEAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHDKYTS-SIP------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28074-1", "uniprot_id": "PSB5_HUMAN", "id": "P28074-1", "name": "Proteasome subunit beta type-5", "aln": "-MALASVLERP---LPVNQR-GFFGLGGRADLLDLGPGSLSDGLSLAA--------PGWGVP-EEP--GIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKR-GPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSG-STP------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P30656-1", "uniprot_id": "PSB5_YEAST", "id": "P30656-1", "name": "Proteasome subunit beta type-5", "aln": "MQAIADSFSVPNRLVKELQYDNEQNLESDFVTGASQFQRLAPSLTVPPIASPQQFLRAHTDDSRNPDCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8BG41-1", "uniprot_id": "PSB11_MOUSE", "id": "Q8BG41-1", "name": "Proteasome subunit beta type-11", "aln": "-MALQDVCKWQ---TPDTPR-------------PSIHLPQAGGWAVPRGCDPQTFLQIHGPR---------LAHGTTTLAFRFRHGVIAAADTRSSCGSYVACPASRKVIPVHQRLLGTTSGTSADCATWYRVLRRELRLRELREGQLPSVAGTAKLLAAMMSCYRGLDLCVATALCGWDHS-GPALFYVYSDGTCLQGDIFSVGSGSPYAYGVLDRGYHYDMTIQEAYTLARCAVAHATHRDAYSGGSVDLFHVRESGWEYVSRSDACVLYRELQKARSLEQELEAKACGIYPEPATPQGARECKELFVEQEEVTPEDCAIIMKTETM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A5LHX3-1", "uniprot_id": "PSB11_HUMAN", "id": "A5LHX3-1", "name": "Proteasome subunit beta type-11", "aln": "-MALQDVCKWQ---SPDTQG-------------PSPHLPRAGGWAVPRGCDPQTFLQIHGPR---------LAHGTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTSGTSADCATWYRVLQRELRLRELREGQLPSVASAAKLLSAMMSQYRGLDLCVATALCGWDRS-GPELFYVYSDGTRLQGDIFSVGSGSPYAYGVLDRGYRYDMSTQEAYALARCAVAHATHRDAYSGGSVDLFHVRESGWEHVSRSDACVLYVELQKL--LEPEPEEDASHAHPEPATAHRAAEDRELSVGPGEVTPGDSRMPAGTETV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1S5-1", "uniprot_id": "Q9W1S5_DROME", "id": "Q9W1S5-1", "name": "Proteasome subunit beta", "aln": "-MALEAICGMNKMPFMRRFDDLQSEWQKEQLREATSNFENPYELMAPPFERPAENLPKILSH---CGIRMDFDHGTTTLGFKYRGGVILCADSRATSGQYIGSQTMRKIVELNDYMLGTLAGGAADCVYWDRVLAKECRLHQLRYRKRMTVDTAARIICNISTEYKGMGLVMGMMLAGFDDE-GPKLIYVDSEGMRSHGQVFSVGSGSPYALGVLDTGYRYDLSDQEAYDLARRAIYHATSKDAYSGGIVRLYHIHSEGWRNICNTDCSDLHDSYCASGCPGNEKDVGNVGDPDNDKPCSSGWTKKNITADNLQTKLATV---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8INY4-1", "uniprot_id": "Q8INY4_DROME", "id": "Q8INY4-1", "name": "Proteasome subunit beta", "aln": "-MALESICGMDKLPFMKSFGYRTSKQTIEEIRVASSNMDNPLAIMAPPYENPRESVKKLNAL---SEVQIDFDHGTTTVGFVYQGGIILCVDSRATSGKLIGSQSIHKVVQVNQYIMGTTAGGAADCTYWDRALTRECRLHELRYKERLPVQSAAKYISNVAAEYKGMGLCMGMMLAGWSPE-GPSLVYVDSNGLRIHGKLFAVGSGAPNALGILDSDYRLDLSDNEAYDLAFLAVYHATMTDIFSGGVVRLYHMDQGNWRNVANKDCQELHEQYSG---------VGNQQTP------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . : *****:.* : *:* ..*:*::.* :. *:: :: ::** :* :*** * * : *: ** : .* ::: :. : *:* .* :. :.*: ** : ** ..* * *..*** * *::* .* :: ::* *. :: *: * :*** * ::*: . .* : * . ", "identical_positions": 54, "similar_positions": 64, "identity": "16.41%" }, { "cls_id": "homologset.agr.SGD:S000006309", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZM3-1", "uniprot_id": "D3ZZM3_RAT", "id": "D3ZZM3-1", "name": "Conserved oligomeric Golgi complex subunit 4", "aln": "MDSPKGCRASAEGTSRARKRRVGTKMADVESPPKLSGAPPPPEGVGGGHCSEISTELIRSLTELQELEAVYERLCGEEKVVEKELDALLEQ-QNTIESKMVTLHRMGPNLQLIEGDAKQLAGMITFTCNLAENVSSKVRQLDLAKNRLYQAIQRADDILDLKFCMDGVQTALRSEDYEQAAAHIHRYLCLDKS---VIELSRQGKEGSMIDAN--LKLLQEAEQRLKAIVAEKFAAATKEGDLPQVERFFKIFPLLGLHEDGLSKFSEYLCKQVASKAEENLLLVLGSDMSDRRAAVIFADTLTLLFEGIARIVETHQPIVETYYGPGR--LFTLIKYLQVECDTQVEKVVNKFIKQRDYHQQFRLVQSNLMR----------------------NSATEKIEPRELDPVLTEVTLMNARSELYLRFLRKRISADFEVGDSMASEEVKQEHQKCLDKLLNN-------CLLSCTMQELVGFYITMEEYFMRETVNKAVALDTYE-KGQLTSSMVDDVFYIVKKCIGRALSSSNIDCLCAMINLATRELEADFRDVLCN------KLRMGFPATTLQDIQRGVTSAVNIMHSSLQQGKFD-------------------------TKGIESTDEAKLSFLVTLNNVEVCSENISTLK--KTLE-----------------------------------------------------------------------EEFNDYEAN---------------------DPWVQQFILSLEQQMAEFKASLSPVIYDSLTGLMTSLVAVELEKVVLKSTFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQMATILNLER-VTEILDYWGA--NSGPLTWRLTPAEVRQVLALRIDFRNEDIKRLRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1U1-1", "uniprot_id": "COG4_MOUSE", "id": "Q8R1U1-1", "name": "Conserved oligomeric Golgi complex subunit 4", "aln": "-------------------------MAEVESPLKLSGAPPPPEGVGGGHCSEISTELIRSLTELQELEAVYERLCGEEKAVEKELDALLEQ-QNTIESKMVTLHRMGPSLQLIEGDAKQLAGMITFTCSLAENVSSKVRQLDLAKNRLYQAIQRADDILDLKFCMDGVQTALRNEDYEQAAAHIHRYLCLDKS---VIELSRQGKEGSMIDAN--LKLLQEAEQRLKAIVAEKFAIATKEGDLPQVERFFKIFPLLGLHEDGLSKFSEYLCKQVASKAEENLLLVLGSDMSDRRAAVIFADTLTLLFEGIARIVETHQPIVETYYGPGR--LFTLIKYLQVECDTQVEKVVNKFIKQRDYHQQFRLVQSNLMR----------------------NSATEKIEPRELDPVLTEVTLMNARSELYLRFLRKRISADFEVGDSMASEEVKQEHQKCLDKLLNN-------CLLSCTMQELIGFYITMEEYFMRETVNKAVALDTYE-KGQLTSSMVDDVFYIVKKCIGRALSSSNIDCLCAMINLATRELEADFRDVLCN------KLRMGFPATTLQDIQRGVTSAVNIMHSSLQQGKFD-------------------------TKGIESTDEAKLSFLVTLNNVEVCSENISTLK--KTLESDCTKLFSQGIGGEQAQAKFDSCLSDL-AAVSNKFRDLLQEGLAELNSSAVKPQVQPWINTFLSVSHSIEEEEFNDYEAN---------------------DPWVQQFILNLEQQMAEFKASLSPVIYDSLTGLMTSLVAVELEKVVLKSTFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQMATILNLER-VTEILDYWGA--NSGPLTWRLTPAEVRQVLALRIDFRNEDIKRLRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H9E3-1", "uniprot_id": "COG4_HUMAN", "id": "Q9H9E3-1", "name": "Conserved oligomeric Golgi complex subunit 4", "aln": "-------------------------MADLDSPPKLSGVQQPSEGVGGGRCSEISAELIRSLTELQELEAVYERLCGEEKVVERELDALLEQ-QNTIESKMVTLHRMGPNLQLIEGDAKQLAGMITFTCNLAENVSSKVRQLDLAKNRLYQAIQRADDILDLKFCMDGVQTALRSEDYEQAAAHTHRYLCLDKS---VIELSRQGKEGSMIDAN--LKLLQEAEQRLKAIVAEKFAIATKEGDLPQVERFFKIFPLLGLHEEGLRKFSEYLCKQVASKAEENLLMVLGTDMSDRRAAVIFADTLTLLFEGIARIVETHQPIVETYYGPGR--LYTLIKYLQVECDRQVEKVVDKFIKQRDYHQQFRHVQNNLMR----------------------NSTTEKIEPRELDPILTEVTLMNARSELYLRFLKKRISSDFEVGDSMASEEVKQEHQKCLDKLLNN-------CLLSCTMQELIGLYVTMEEYFMRETVNKAVALDTYE-KGQLTSSMVDDVFYIVKKCIGRALSSSSIDCLCAMINLATTELESDFRDVLCN------KLRMGFPATTFQDIQRGVTSAVNIMHSSLQQGKFD-------------------------TKGIESTDEAKMSFLVTLNNVEVCSENISTLK--KTLESDCTKLFSQGIGGEQAQAKFDSCLSDL-AAVSNKFRDLLQEGLTELNSTAIKPQVQPWINSFFSVSHNIEEEEFNDYEAN---------------------DPWVQQFILNLEQQMAEFKASLSPVIYDSLTGLMTSLVAVELEKVVLKSTFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQMATILNLER-VTEILDYWGP--NSGPLTWRLTPAEVRQVLALRIDFRSEDIKRLRL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q29RB1-1", "uniprot_id": "COG4_DANRE", "id": "Q29RB1-1", "name": "Conserved oligomeric Golgi complex subunit 4", "aln": "-------------------------MEEAASPARRRGGPAG--------VSAVQTDTIEALTELEDLERVYAQLCAEEAEVQVELDALVGQ-QNNIETKMLSLQRMGPNLQLIEGDAVQLSGMINFTCSLAENVSSKVRQLDLTKKRLYQAIQRADDILDLKFCTDGVQTALRNQDYEQAAAHIHRYLSLDQS---VIELSKQGGEGSAVEAS--LALLQEAERNLKTLVTTRLEEAVATGDLPQVERFFKILPLLGLHEQGLARFAQYLCSQLASKAEENLILAVGSDLGERRAPVIFADTLTLLLEGIARIVETHQPIVETYYGPGR--LHTLLAHLQKECDKQAQKIVDKFIQQRDYNNKFQVVQSNMMR----------------------GMTTDKIEPRDLDPVLCEVTLMNSRAELYFRFLRRRIVADFEVADAMADEAVIQEHQQSLEQLLKN-------CQLSRTMQELIGYYIPMEEYYMRESVNKAVAMDTAE-VGQLSSSVVDDVFYIVKKCISRALTSSSSDCVCAMINHATSVLETDFREVLVC------KLRAGYPVSALQDLQRGVSSAVSLMQSSLQQGKITNLT---------------------QTLGIESQEQAKSAYLVTLNNVEVCSENISTLK--KNLESDCAKLFSQGASSDHAKEKIDSCLSDL-VNTSSKFKDLLQEGLQELNNTAIRPQVKPWISSFLSVSHNIEEEEFSEYEAN---------------------DPFVQQLIVQLEQLMAEFKVGLSPVIYDTLTSLMTSLIAMEMEKTVFKCTFSRLGGLQFDKELRALVAYLSSVTSWTIRDKFARLTQMATILNLER-VSEILDYWGP--NSGPLTWRLTPAEVRQVLALRVDFRSEDIKRLRL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q95TN4-1", "uniprot_id": "COG4_DROME", "id": "Q95TN4-1", "name": "Conserved oligomeric Golgi complex subunit 4", "aln": "-------------------------------------------------MSVLEQLGALDIGTNEQVDETLQRIADEEAKVNEKLESLLAK-QCQIEAKMSGIGRSLSLLHTVDSDSNKLNDQIVNTAQLAESVSAKVRRLDLARCRASECQQRVHDLIDLHLCSQGVVKAIGEEDYEKSATHIARFLAMDQQ---LLRRTADDVQGSITSVSDAVKTLEDATEKTRVLIAKRFDEAVKADDLASVERFFKIFPLVGCHRTGIEKFSLYICQKLANKAQKELRNAQDIAKAESRLQLAYADRLTAILENFARVVEVNQPIIEAFYGQASSSLIDMVSILQHECDTEVKNLLMEFNKNRQIQYRSKQVNESTQRSAGGGNLGSNSIQALGHYRKPSGGSVDKLNPKEIDAIIAEITVMHARVELYFRFMRRRLQVHVET---CVPEKEQFDIMERYEKIMKN-------SDLRRQMQEILSTYLLLERYFMEESVLKAIGLDTYE-SGQQCSSMVDDVFFILRKSIRRALTTQSINGTCAVINNVAACLDGDFVNALKA------PLKSGYPSGYID-----LAQAYNAIQTSLQQGKLH----------------------------SSDADRGRANFLVQLNNADISTEYIETLC--QTMEQEIAGTFPQTTQVER--QMLDSCLTEL-KAVRDALKATVDFGMQQLRSSVIKPRLNPWINQFLNYSHNLNEEELAAYEAG---------------------ETFVQFFIVQLDGLLNSFKNSLSPRNYDALVSILATEVTIQLERAIKKISFNRLGGLVLDQEVRALGSYLTGATSWSVRDKMTRISQIATLLNLDK-ITELSEYWNPENNKEMSSWHLTPNEVRTFLTLRNDFRIEDIKRLQL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06096-1", "uniprot_id": "COG4_YEAST", "id": "Q06096-1", "name": "Conserved oligomeric Golgi complex subunit 4", "aln": "----------------------------MEGQKSNASWESSIIEGQLSKNLARYTLLLDKLSTLSQIDKLSEVIANDYAKQSKQLNAFVQQSQSSLNKESRKLELQRTNLTTTLTQFHETVATISSSNARAKAIHDDIETVDQERALVNKTLQFVKDVRTLKNNISLAHSALETKDYLVAATAINEIRSLPDKKLIVSEFAKKVVPSSEIPEE-PAILIKNWCKELTSLFQEQFMEATRTQDIKELTLMFKMFPMIGQDVLGLDLYSKYVCDIIADESRK---IMSNSMENSTKFQGFFSQVLLHLFKIVSTIINDHSKVIATCYGKKH--MVHVMEKVEKEADLQASLILDIFMETRKIERTIHDINEWEHSQKNEDVNIDSNQSDIETDG--ETEKSSIISIHDLALLIMEFSQILQNWSMYSRFYSVKWNEFSDLHPHVLQPPPPIADGKFALKLKQDKVFDEFQVFVLNHLQRSFRNSISLEELPSLNDLITAVPLNDHDNISYPVTSVLDDLILLVRKNLISVVNTGQFKLLASFLNELVKFFQNRFLVKFMQNKFKLLQSKLASNVSLKRYIPKGEEQSATSRSVSPPANKFSPLSRFTFRGAAASALTNIQSNLQAVVAEDEDSILALHHYLIYLNTLYLSKVYVHRLLSIEILEDDSQRILRDNFPFDNDAAQLQNLIINSEKLVLEQTDKLSKWAVKYLFQNILQNRVRNLLGTVFVNSASSNSSTSNQKNVSRDYSAGSNQKNYITSIEDFEDLSQINSFNSKWNQLIIPYKNILHNEAYAELLSVIVDYIVTTLEQRIWTLEFNELGVTKLDRELSLFIGNMCGLN-YNLREKFLKLTQIVLLLGLDDDNFDLTTGDIKDDFNGTFDWVINSQERIKARNMKIDRTQ--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .::: :. : . :*:::: : * :: : : . * : : * : *: : .:. :* : : * ..*: *: . . .*: :** :*: . .: .. : . : . .* . ::: .. :. :: *. *: .: :**::*::* . *: :: *:*. :*.::.: . . : ::: * ::: .: ::: :. :: : ** : :: :: *.* :.. :: * : *. . : ::. . :. ::: :: *.: : . .:* ** : : : :: :: : :*. . : :*. : : .*: :: : . :*::**:: :::* : .:.: . . .:.:* . :: * : : . .: . * .*: .. . :*: **. :.. : * : :* . :.. . :: : . : : :* * * * .::. :. :*: : . *..** :*:*: : . : . :.:*:*: :::*:. :*.*: :: . * :.. * :: * ", "identical_positions": 69, "similar_positions": 250, "identity": "7.62%" }, { "cls_id": "homologset.agr.SGD:S000006311", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LZV4-1", "uniprot_id": "A0ABK0LZV4_RAT", "id": "A0ABK0LZV4-1", "name": "Cleavage and polyadenylation specificity factor subunit 4", "aln": "MEEVIAGLQGFTFTFEQDVELQRGTGLLPFQGMDKSSSAVCNFFAK----GLCVKGMLCPLRHEQ--GEKMVVCKHWLRGLCRKSDCCNFLHQYDVSRMPVCYFHSKFGNCNNK-ECPFLHLKPVPKLQDCPWYDQGFCKEVGPLCKYRHVHQVLCPNYFIGFCPKGP-KCQFGHPKMSPI-------------LHRSN--MKPIN------------------------------------------QLWDSTTSTGN-----TLVPHSQAKATVHHQKRWSLPPACSSRAHLAP--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3UWW6-1", "uniprot_id": "G3UWW6_MOUSE", "id": "G3UWW6-1", "name": "Cleavage and polyadenylation specificity factor subunit 4", "aln": "MEEVIAGLQGFTFAFELDVESQKGTGLLPFQGMDKSSSAVCNFFAK----GLCVKGMLCPLRHEQ--GEKLVVCKHWLRGLCRKSDCCDFLHQYDVSKMPVCYFHSKFGNCSNK-ECLFLHLKPVLKLQDCPWYNQGFCKEVGPLCKYRHVHQVLCPNYFTGFCPEGP-QCQFGHPKMSPP-------------FHPSNVKLQPVN------------------------------------------QPWDSTTSTGN-----TLVSPFQAKPMVHGQRRWSLPQACSSRAHPAP--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NMK7-1", "uniprot_id": "CPS4L_HUMAN", "id": "A6NMK7-1", "name": "Putative cleavage and polyadenylation specificity factor subunit 4-like protein", "aln": "MQEVIAGLERFTFAFEKDVEMQKGTGLLPFQGMDKSASAVCNFFTK----GLCEKGKLCPFRHDR--GEKMVVCKHWLRGLCKKGDHCKFLHQYDLTRMPECYFYSKFGDCSNK-ECSFLHVKPAFKSQDCPWYDQGFCKD-GPLCKYRHVPRIMCLNYLVGFCPEGP-KCQFAQ-------------------------------------------------------------------------KIREFKLLPGS-----KI--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BQZ5-1", "uniprot_id": "CPSF4_MOUSE", "id": "Q8BQZ5-1", "name": "Cleavage and polyadenylation specificity factor subunit 4", "aln": "MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLK----AACGKGGMCPFRHIS--GEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKF----------------------------------GPLCRHRHTRRVICVNYLVGFCPEGP-SCKFMHPRFELP-------------MGTTEQPPLPQQTQPPTK--------------------------RAPQVIG---VMQSQNSSAGN-----RGPRPLEQVTCYKCGEKGHYANRCT-KGHLAFLSGQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95639-1", "uniprot_id": "CPSF4_HUMAN", "id": "O95639-1", "name": "Cleavage and polyadenylation specificity factor subunit 4", "aln": "MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLK----AACGKGGMCPFRHIS--GEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNK-ECPFLHIDPESKIKDCPWYDRGFCKH-GPLCRHRHTRRVICVNYLVGFCPEGP-SCKFMHPRFELP-------------MGTTEQPPLPQQTQPPAKQSNNPPLQRSSSLIQLTSQNSSPNQQRTPQVIG---VMQSQNSSAGN-----RGPRPLEQVTCYKCGEKGHYANRCT-KGHLAFLSGQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5FVR7-1", "uniprot_id": "CPSF4_RAT", "id": "Q5FVR7-1", "name": "Cleavage and polyadenylation specificity factor subunit 4", "aln": "MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLK----AACGKGGMCPFRHIS--GEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNK-ECPFLHIDPESKIKDCPWYDRGFCKH-GPLCRHRHTRRVICVNYLVGFCPEGP-SCKFMHPRFELP-------------MGTTEQPPLPQQTQPPTK--------------------------RAPQVIG---VMQSQNSSAGN-----RGPRPLEQVTCYKCGEKGHYANRCT-KGHLAFLSGQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AUI5-1", "uniprot_id": "A0A8I6AUI5_RAT", "id": "A0A8I6AUI5-1", "name": "Cleavage and polyadenylation specificity factor subunit 4", "aln": "---IVP----ILFALEITMEQQLGAQQLSFPSMDKSGAAVCEFFVK----AACGKGGMCPFCHIS--GEKTVVCQHWLRGLCKKGDQCEFLHKYDITKMLECYFYSKFWKCSGK-DCSFVHMDPESKIKDCPWYDCSFCKH-GPLCRYQHTRRVLCVNYLVGFCPGG-------HPLPGLA-------------LTVGEVPGSPG---------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VPT8-1", "uniprot_id": "CPSF4_DROME", "id": "Q9VPT8-1", "name": "Cleavage and polyadenylation specificity factor subunit 4", "aln": "MDILLANVSGLQFKAERDLIEQVGAIPLPFYGMDKSIAAVCNFITRNG--QECDKGSACPFRHIR--GDRTIVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSRFNACHNK-ECPFLHIDPQSKVKDCPWYKRGFCRH-GPHCRHQHLRRVLCMDYLAGFCPEGP-SCKHMHPHFELPPLAELGKDQLHKKLPTCHYCGELGHKANSCKQYVGSLEHRNNINAMDHSGGHSGGYSGHSGHIEGADDMQSNHHSQPHGPGFVKVPTPLEEITCYKCGNKGHYANKCP-KGHLAFLSNQHSHK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06102-1", "uniprot_id": "YTH1_YEAST", "id": "Q06102-1", "name": "mRNA 3'-end-processing protein YTH1", "aln": "MSLIHPDTAKYPFKFEPFLRQEYSFSLDPDR-------PICEFYNSREGPKSCPRGPLCPKKHVLPIFQNKIVCRHWLRGLCKKNDQCEYLHEYNLRKMPECVFFSKNGYCTQSPDCQYLHIDPASKIPKCENYEMGFCPL-GSSCPRRHIKKVFCQRYMTGFCPLGKDECDMEHPQFIIP-------------------------------------------------------------------DEGSKLRIKRD-----------DEINTRKMDEEKERRLNAIINGEV----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * * : : . . .:*:* * :* ** * :. :**:*******:*.* *.:**:*:: :* * *.*: *. * :* :::* *: **** * : ", "identical_positions": 38, "similar_positions": 31, "identity": "12.5%" }, { "cls_id": "homologset.agr.SGD:S000006312", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M4M7-1", "uniprot_id": "A0ABK0M4M7_RAT", "id": "A0ABK0M4M7-1", "name": "26S proteasome non-ATPase regulatory subunit 6", "aln": "---MPLENLEEEGLP----KNPDLRIAQLRFLLSLPEH--RGDTAVREELMAAVRENNMAPYYEALCKSLDWQ--------------------MDMDLLSKMKKANEEELKRLDEELEDAEKN-LGESEIRDAMMAKAEYLCQIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHS---LPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAP-HYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JI4-1", "uniprot_id": "PSMD6_MOUSE", "id": "Q99JI4-1", "name": "26S proteasome non-ATPase regulatory subunit 6", "aln": "---MPLENLEEEGLP----KNPDLRIAQLRFLLSLPEH--RGDAAVREELMAAVRENNMAPYYEALCKSLDWQ--------------------MDVDLLSKMKKANEEELKRLDEELEDAEKN-LGESEIRDAMMAKAEYLCQIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHS---LPAVRQYLFSLYECRYSVFFQSLAIVEQEMKKDWLFAP-HYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVDFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15008-1", "uniprot_id": "PSMD6_HUMAN", "id": "Q15008-1", "name": "26S proteasome non-ATPase regulatory subunit 6", "aln": "---MPLENLEEEGLP----KNPDLRIAQLRFLLSLPEH--RGDAAVRDELMAAVRDNNMAPYYEALCKSLDWQ--------------------IDVDLLNKMKKANEDELKRLDEELEDAEKN-LGESEIRDAMMAKAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHS---LPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAP-HYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3G7-1", "uniprot_id": "PSMD6_DROME", "id": "Q9V3G7-1", "name": "26S proteasome non-ATPase regulatory subunit 6", "aln": "---MPAENLEEQGLE----KNPNLELAQTKFLLTLAEY--KQDAALKAKLLEAIRTENMAPWYEHICSELGWT--------------------VDKDLLARMKENNRVEVEQLDAAIEDAEKN-LGEMEVREANLKKSEYLCRIGDKAAAETAFRKTYEKTVSLGHRLDIVFHLIRLGLFYLDHDLITRNIDKAKYLIEEGGDWDRRNRLKVYQGVYSVAVRDFKAAATFFLDTVSTFTSYELMDYPTFVRYTVYVAMIALPRNELRDKVIKGSEIQEVLHG---LPDVKQFLFSLYNCQYENFYVHLAGVEKQLRLDYLIHP-HYRYYVREMRILGYTQLLESYRSLTLQYMAESFGVTVEYIDQELARFIAAGRLHAKVDRVGGIVETNRPDNKNWQYQATIKQGDLLLNRIQKLSRVINI------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06103-1", "uniprot_id": "RPN7_YEAST", "id": "Q06103-1", "name": "26S proteasome regulatory subunit RPN7", "aln": "MVDVEEKSQEVEYVDPTVNRVPNYEVSEKAFLLTQSKVSIEQRKEAAEFVLAKIKEEEMAPYYKYLCEEYLVNNGQSDLEHDEKSDSLNEWIKFDQELYNELCKKNESKIKELNEKIQKLEEDDEGELEQAQAWINLGEYYAQIGDKDNAEKTLGKSLSKAISTGAKIDVMLTIARLGFFYNDQLYVKEKLEAVNSMIEKGGDWERRNRYKTYYGIHCLAVRNFKEAAKLLVDSLATFTSIELTSYESIATYASVTGLFTLERTDLKSKVIDSPELLSLISTTAALQSISSLTISLYASDYASYFPYLLETYANVLIPCKYLNRHADFFVREMRRKVYAQLLESYKTLSLKSMASAFGVSVAFLDNDLGKFIPNKQLNCVIDRVNGIVETNRPDNKNAQYHLLVKQGDGLLTKLQKYGAAVRLTGSDRV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. * : : : *: .::: ***: .: . :: :: ::***:*: :*.. .* :* .: : *. :::.*: ::. *:: ** * :* : .** .:**** * .:: *: .*::: * ::*::: : *:*:** *: :..: : .: :**:****:**** *.* *::.:*:*:** ** :::*:::**** ** .* ::. *: ..:::* * :*:.***...*: .:: * : . :*** . * :: * . :: * ::***** *:******::*:* **.:*** * ::*::*.:**. :*:. :*:*. ********.** **: :*:** **.::** . .:.: ", "identical_positions": 123, "similar_positions": 149, "identity": "28.67%" }, { "cls_id": "homologset.agr.SGD:S000006314", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52432-1", "uniprot_id": "RPAC1_MOUSE", "id": "P52432-1", "name": "DNA-directed RNA polymerases I and III subunit RPAC1", "aln": "MAAAQAVEEMRTRVVLGEFGVRNVHTTDFPGNYAGYDDAWDQNRFEKNFRVDVVQMDEDTLEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPILADPRLFEYR---NQGEEEGTEIDTLQFRLQVRCTRNPNAAKDSSDPNELYVNHKVYTRHMTWVPLGNQADVFPEGTIRPVHDDILIAQLRPGQEIDLMMHCVKGIGKDHAKFSPVATASYRLLPAITLLEPVEGEAAEELSQCFSPGVIEVEEVQGKKVARVANARLDTFSREIFRHEKLKKAVRLARVRDHYIFSVESTGVLPPDVLVSEAIKILMGKCRRFLDELDAVEMD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15160-1", "uniprot_id": "RPAC1_HUMAN", "id": "O15160-1", "name": "DNA-directed RNA polymerases I and III subunit RPAC1", "aln": "MAASQAVEEMRSRVVLGEFGVRNVHTTDFPGNYSGYDDAWDQDRFEKNFRVDVVHMDENSLEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPRLFEYR---NQGDEEGTEIDTLQFRLQVRCTRNPHAAKDSSDPNELYVNHKVYTRHMTWIPLGNQADLFPEGTIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDITLLEPVEGEAAEELSRCFSPGVIEVQEVQGKKVARVANPRLDTFSREIFRNEKLKKVVRLARVRDHYIFSVESTGVLPPDVLVSEAIKVLMGKCRRFLDELDAVQMD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VMX3-1", "uniprot_id": "Q9VMX3_DROME", "id": "Q9VMX3-1", "name": "DNA-directed RNA polymerases I and III subunit RPAC1", "aln": "MASKNRKEPL---LYMEEYRVK-----QDPQDYGLADDVFSVQAFKEKLHIKIVRNDEDGLEFDLIGVYPAIANAFRRLMLSDVPSMAIEKVYIYNNTSIIQDEVLAHRMGLLPLRADPRLFAYRT--EESTEAGTEQDTLEFELKVKCSRRRDAGKDQSNFDDIYKNHKVYSGHLKWLPKGKQAQIYSESAVNCIHDDILIAQLRPGHELDLRLVAVKGLGRDHAKFSPVATATYRLLPMIKLNREVTGKDAYLLQNCFSPGVIGIDENE---TAYVKDARYDTCSRNVYRYPQLNDAVTLARIRDHYIFSVESVGALKPDVIFLEAVKVLKRKCRALIDEIEAE---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07703-1", "uniprot_id": "RPAC1_YEAST", "id": "P07703-1", "name": "DNA-directed RNA polymerases I and III subunit RPAC1", "aln": "MSNIVG---------IEYNRVTNTTSTDFPGFSKDAENEWNVEKFKKDFEVNISSLDAREANFDLINIDTSIANAFRRIMISEVPSVAAEYVYFFNNTSVIQDEVLAHRIGLVPLKVDPDMLTWVDSNLPDDEKFTDENTIVLSLNVKCTRNPDAPKGSTDPKELYNNAHVYARDLKFEPQGRQSTTFADCPVVPADPDILLAKLRPGQEISLKAHCILGIGGDHAKFSPVSTASYRLLPQINILQPIKGESARRFQKCFPPGVIGIDEGS--DEAYVKDARKDTVSREVLRYEEFADKVKLGRVRNHFIFNVESAGAMTPEEIFFKSVRILKNKAEYLKNCPITQ---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : * : * :: :. : *::.:.:.: * :**::.: .:*******:::::**::* * * .:****::***:****:**:*: .** :: : . * *: :*: : *:*:*:*. .* *..:: .::* * :**: .:.: * *.*: :.: .: . ***:*:****:*:.* .: *:* ********:**:***** *.: . : *: * :..**.**** ::* . * * :.* ** **:: * :: . * *.*:*:*:**.***.*.: *: :. :::::* *.. : : : ", "identical_positions": 110, "similar_positions": 123, "identity": "31.52%" }, { "cls_id": "homologset.agr.SGD:S000006316", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R3C6-1", "uniprot_id": "RBM19_MOUSE", "id": "Q8R3C6-1", "name": "Probable RNA-binding protein 19", "aln": "MSRLIVKNLPNGMKEERFRQLFAAFG---------------TLTDCSLKFTKDGKFRKFGFIGFKSEEEAQAALNHFHRSFIDTTRITVEFCKSFGDPSKPRAWSKHAQKS--------SQPKQPSQDSVPSDTKKDK-KKK-GPSDLEKLKEDAKFQEFLSIHQKRTQVATWANDALEAKLP----------KAKTKASSDYLNFDSDSNSDSGQESEEEPAREDPEEEQGLQPKAAVQKELSDMDYLKSKMVRAEVSSEDEDEEDSEDEAVNCEEGSEEEEEEGSPASPAKQ-----GGVSRGAVPGVLRPQEAAG------------------------------------------------------KVEKPVSQKEPTTPYTVKLRGAPFNVTEKNVIEFLAPLKPVAIRIVRNAHGNKTGYVFVDLSSEEEVKKALKCNRDYMGGR--YIEVFREKQ--APTAR-GPPKS-TTPWQGRTLGENEE-----EEDLADSGRLFVRNLSYTSSEEDLEKLFSAYGPLSELHYPIDSLTKKPKGFAFVTFMFPEHAVKAYAEVDGQVFQGRMLHVLPST-IKKEAS-QEANAPGSS-YKKKKEAMDKANSSSSHNWNTLFMGPNAVADAIAQKYNATKSQVFDHETRGS-VAVRVALGETQLVQEVRSFLIDNGVCLDSFSQAA--AERSKTVILAKNLPAGTLAAEIQETFSRFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPIGVFG-AAPQKKDSQ--HEQPAEKAEVEQETVLD---PEGEKASVEGAEASTGKMEEEEEEEEEEEEE-SIPGCTLFIKNLNFSTTEETLKGVFSKVGAIKSCTISKKKNKAG--VLLSMGFGFVEYKKPEQAQKALKQLQGHTVDGHKLEVRISERATKP-ALTST-RKKQVPKKQTTSKILVRNIPFQANQREIRELFSTFGELKTVRLPKK-MTGTGAHRGFGFVDFITKQDAKKAFNALCHSTHLYGRRLVLEWADSEVT--VQTLRRKTARHFQ---EPPKKKR-SAVLDGILEQLEDEDNSDGEQALQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LLW4-1", "uniprot_id": "A0ABK0LLW4_RAT", "id": "A0ABK0LLW4-1", "name": "Probable RNA-binding protein 19", "aln": "MSRLIVKNLPNGMKEDRFRQLFAAFG---------------TLTDCSLKFTKEGKFRKFGFIGFKSEEEAQAALNHFHRSFIDTSRITVEFCKSFGDPSKPRAWSKHAQKP--------SQPKQPSQDSIPSDTKKDK-KKKKVPSDLEKLKEDAEFQEFLSIHQKRTQVATWANDALEAELP----------KAKAKPSSDYLNFDSDSNSDSGQESEEEPAGEDGEEEQGLQPKAAVQKELSDMDYLKSKMVRAEVSSEDEDKEDSEDEAVNCEEGSEAEEEEGSPTCPAQQ-----AGVNRGAVLGSLRPQEAAGKALRTAASYSSLRAQLNSQQGFSWISPAPLPAPGVPATTCHTSKRQAFTIFVISQVEKPASQKEPTTPYTVKLRGAPFNVTEKNVLEFLAPLKPVAIRIVRNAHGNKTGYVFVDLSSEEEVKKALKCNREYMGGR--YIEVFREKQ--ASAAR-GAPKSSSAPWQGRTLGEHEE-----EEDLADSGRLFVRNLSYTSSEEDLEKLFSAYGPLSELHYPIDSLTKKPKGFAFVTFMFPEHAVKAYAEVDGQVFQGRMLHVLPST-IKKEAN-QEANAPGSS-YKKKKEAMDKANSSSSHNWNTLFMGPNAVADAIAQKYNATKSQVFDHETKGS-VAVRMALGETQLVQEVRSFLIDNGVCLDSFSQAA--AERSKTVILAKNLPAGTLAAELQEIFSRFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPIGVFG-AAPQKKDSQ--PEQPAQKAEAEQETVLN---PEGEKALVEGAEASMGKMEEEEEEEEEEEEEESIPGCTLFIKNLNFNTTEETLKEVFSRVGAVKSCTISKKKSKAG--VLLSMGFGFVEYKKPEQAQKALKRLQGHIVDGHKLEVRISERATKP-ALTST-RKKQVPKKQTTSKILVRNIPFQANQREIRELFSTFGELKTVRLPKK-MTGTGAHRGFGFVDFITKQDAKKAFNALCHSTHLYGRRLVLEWADSEVT--VQALRRKTAKHFQ---EPPKKKR-SAVLDGILEQLEDGDDSDSEETLQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y4C8-1", "uniprot_id": "RBM19_HUMAN", "id": "Q9Y4C8-1", "name": "Probable RNA-binding protein 19", "aln": "MSRLIVKNLPNGMKEERFRQLFAAFG---------------TLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKP--------SQPKQPPKDSTTPEIKKDE-KKKKVAGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPS----------KGKSKPASDYLNFD----SDSGQESEEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEE-SEDEAVHCDEGSEAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARA------------------------------------------------------ETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGR--YIEVFREKN--VPTTK-GAPKNTTKSWQGRILGENEE-----EEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPST-IKKEAS-EDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNAVADAIAQKYNATKSQVFDHETKGS-VAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAA--AERSKTVILVKNLPAGTLAAQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPVGVFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEEEEEEES--LPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAG--VLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKP-AVTLA-RKKQVPRKQTTSKILVRNIPFQAHSREIRELFSTFGELKTVRLPKK-MTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHLYGRRLVLEWADSEVT--LQALRRKTAAHFH---EPPKKKR-SVVLDEILEQLEGSDSDSEEQTLQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QF98-1", "uniprot_id": "F1QF98_DANRE", "id": "F1QF98-1", "name": "Probable RNA-binding protein 19", "aln": "MSRLIVKNLPNGMKEDRFRKMFADFG---------------TLTDCALKFTKDGKFRKFGFVGFKTEEDAQKALKHFNKSFVDTSRVTVELCTDFGDPNKARPWSKHTRQP--------SSKKDTEEKKTHEQGEKEKKKPKKILNVLGDLEKDESFQEFLAVHQKRGQVPTWANDTVEATAVRPEMEKKKEKKQKAAVEDDYLNFD----SDESEESSDDGEDAADEEDKQDNEKEALKTGLSDMDYLRSKMVEK-SDMLDEKDDDSSASAADENEEDEGKEEEESIVQHADS------AYESGEKTSSQKS-------------------------------------------------------------TRPA--IEPTTEFTVKLRGAPFNVKEQQVKEFMMPLKPVAIRFAKNSDGRNSGYVYVDLRSEAEVERALRLDKDYMGGR--YIEVFRANN--FKNDRRSAKRSEMEKNFVRELKDDEE-----EEDVAESGRLFIRNMPYTCTEEDLKEVFSKHGPLSEVLFPIDSLTKKPKGFAFVTYMIPENAVSALAQLDGHTFQGRVLHVMASR-LKKEKADQGPDAPGSSSYKRKKDAKDKAASGSSHNWNTLFLGTSAVADAIAEKYNTTKSQVLDHESDGS-LAVRMALGETQIVQETRQFLLDNGVSLDSFSQAS--GERSKCVILVKNLPSGVQVADLEALFSPHGSLGRVLLPPSGLTAIVEFLEPTEAKRAFMKLAYTKFQHVPLYLEWAPVAVFTTPSAPRPEPQ-TKEKSAVKNDSVQN---------------------------EEEEEEEEEDDQILPGSTLFIKNLNFITSEETLQKTFSKCGVVKSCTISKKRDKAG--KLLSMGYGFVQYKTPEAAQKAMRQLQHCTVDEHQLEVKISEREVKS-GVAQAKRKKQTARKQTTSKILVRNIPFQATVKELRELFCTFGELKTVRLPKK-GIG-GSHRGFGFIDFLTKQDAKKAFSALCHSTHLYGRRLVLEWADAEET--VDDLRRKTAQHFH---DAPKKKRKAEVLEGILEQMEVGDGDGE------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VT19-1", "uniprot_id": "Q9VT19_DROME", "id": "Q9VT19-1", "name": "RRM domain-containing protein", "aln": "MSRIIVKQLPKHITEDKLRQIFGAQG---------------TITDLQLKYTPDGKFRQFCFVGYSTEEEAQSAIRHFDNTCIQTSRVRVESCAALGSEDKPQSWSKYAKDSKKNLDKLKEKEREAAAKAKESEKKKKKDKVDKVDQILSRHKDDPEFQEFLEAHDKSR--TLWGND---------------------------LGIN------KNRENEEE-DDEEQEESRAARDDSGVDADAG-------------------DEDGSGDEADEEEDTDKLAEKPISDLEYMKS-----LMATTSGEATAKKP--------------------------------------------------------------KAKADKSNLELFTIKIHNVPYNTKRQEVLKFFKPLKPYSVRLPSKVHG----FCYVGFKTEKDMAKGMLKNKSFIKGKQVFFSDFTEKNKVTKASKSGQPLAPAAVDAGNAKWKHQQDSLSKEDDISESGRIFFRNLAYTTTEEDLRKLFEQFGPVVEVNLPLDKLTRKIKGFGTVTYMMPEHALKAFNTLDGTDFHGRLLHLLPSKDIEKNPKEDLDENDASLSFKEKKALKLKKNAQKPIGWNTLFLGANAVAEILAKQFKTSKERILDTSDGGSSAAVRLALGETQVVIEMKRFLEEEGVRLDAFDEPA--KKRSNTVILAKNLPAATEISEITPIFSRFGPIGRIVLPPSGVTALIEYCDPLEARQAFKKLAYSKFKNAPLYLEWAPEQVFTKTLSGEPVIPKSEPKPKEEVKPEEKPIVN------------------DAKPDEEDSRAEDADDEPEPNTTLFLRNLNFKTVQETVEKHFRHLGSIHTVEIAKRRDPENPREFKSLGYGFIQFKKSSVAEHALKNLQLTHIDGNPVELKRSDRVLKTQDNDGAQRRLASQKKQTGTKILVRNIPFQAQYREVRDIFKAFGELRSLRIPKKATTGEDAHRGFGFVDYMSKAEAKRAFDALSASTHLYGRRLVLEWSANDDNQDVEELRKRTAAKFDGSQAATAAKRSRKSFFDVEGSVQPNQDDDEEEEQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06106-1", "uniprot_id": "MRD1_YEAST", "id": "Q06106-1", "name": "Multiple RNA-binding domain-containing protein 1", "aln": "MSRIIVKGLPVYLTDDNLREHFTKRLRQKHSHQAVNGSGPDLITDVKILRDRNGESRRFGFIGYRNEEDAFDAVEYFNGSFINTSKIEVSMAKSFADPRVPQPMKEKRREALK------RFREKEEKLLQEENRKKKKVDENKHSNIDDEIRKNKQLQEFMETMKPSSQVTSWEKVG-------------------------------------IDKSIEDEKLKREEEDSSVQGNSLLAHALALK------------------EENNKDEAPNLVIENESDDEYSALNRNRDE--------------------------------------------------------------------------------DQEDAGEEEKMISISNLKDTDIGLVNDDANSDEKENEKRRNLAQDEKVSDLDWFKQRRVRIKESEAETREKSSSYATEQNESLDTKKEEQ---------PERAVPQKTDEELAIEKIN----------QTGRLFLRNILYTSKEEDFRKLFSPFGELEEVHVALDTRTGQSKGFAYVLFKDSKNAVNAYVELDKQIFQGRLLHILPGE-EKKSHRLDEFDLKNMPLKKQKELKRKAAASRQTFSWNSLYMNQDAVLGSVAAKLGLEKSQLIDAENSSS--AVKQALAEAHVIGDVRKYFESKGVDLTKFSQLKSTNQRDDKVILVKNFPFGTTREELGEMFLPYGKLERLLMPPAGTIAIVQFRDTTSARAAFTKLSYKRFKDGIIYLERGPKDCFTKPAEADDLINNTSAKEEENPVEVKPSSND--------------LMEANKDVTEGSSNAHDEDVIDGPTVSIFIKNLNFSTTNQNLTDRFKVFTGFVVAQVKTKPDPKHQGKTLSMGFGFVEFRTKEQANAVIAAMDGTVIDGHKIQLKLSHRQASQ------SGNTKTKSNKKSGKIIVKNLPFEATRKDVFELFNSFGQLKSVRVPKK---FDKSARGFAFVEFLLPKEAENAMDQLHG-VHLLGRRLVMQYAEEDAVDAEEEIARMTKKVRK---QVATNEMAALRNGGGRKKLDVDDEENEGF----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*** ** :.::.:*: * :** : :*: *:* *:*: .**:* * .:*. : ::*::: *. . :.. .:. .: :.. .. : :*.: . . ..: .:***: . . * : :. :: **. . . : . .: . .* . .: :: : .. : . :::.. . ..:. . : : . : . : . . . .: : :. :: . .. : ::**:*.**: ** .***:.::*. .* : *: .:*. * : ***. : : .::*:.* :* *:**:**::.. :*. : . *.*: : .. .**:*::. .** :* : *.:::* . .* **: **.*:::: : : :: .:** * *.: :*.. ***.**:* .. :: * .* : *:::* .* *:::: :. .*: ** :*:*.:*:. :*** .* * . : : * ... .: : * ::*::**** * ::.: * . : .: . *:*:**::::. . *: .: :: :* : :::: *.* . . ::. **:*:*:**:* ::: ::* :**:*:::*:*** : ***.*:::: :*:.*:. * .** *****:::: : : : : * . . : .:: : .. ", "identical_positions": 150, "similar_positions": 302, "identity": "13.88%" }, { "cls_id": "homologset.agr.SGD:S000006317", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70500-1", "uniprot_id": "CDIPT_RAT", "id": "P70500-1", "name": "CDP-diacylglycerol--inositol 3-phosphatidyltransferase", "aln": "---------MPEENIFLFVPNLIGYARIVFAIISFYFMPCCPFTASSFYLLSGLLDAFDGHAARALNQGTRFGAMLDMLTDRCATMCLLVNLALLYPRATLLFQLSMSLDVASHWLHLHSSVVRGSESHKMIDLSGNPVLRIYYTSRPALFTLCAGNELFYCLLYLFNFSEGPLVGSVGLFRMGLWITAPIALLKSIISVIHLVTAARNMAALDAADRAKKK------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDP6-1", "uniprot_id": "CDIPT_MOUSE", "id": "Q8VDP6-1", "name": "CDP-diacylglycerol--inositol 3-phosphatidyltransferase", "aln": "---------MPEENIFLFVPNLIGYARIVFAIISFYFMPCCPFTASSFYLLSGLLDAFDGHAARALNQGTRFGAMLDMLTDRCATMCLLVNLALLYPRATLLFQLSMSLDVASHWLHLHSSVVRGSESHKMIDLSGNPVLRIYYTSRPALFTLCAGNELFYCLLYLFNFSEGPLVGSVGLFRMGLWVTAPIALLKSVISVIHLITAARNMAALDAADRAKKK------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14735-1", "uniprot_id": "CDIPT_HUMAN", "id": "O14735-1", "name": "CDP-diacylglycerol--inositol 3-phosphatidyltransferase", "aln": "---------MPDENIFLFVPNLIGYARIVFAIISFYFMPCCPLTASSFYLLSGLLDAFDGHAARALNQGTRFGAMLDMLTDRCSTMCLLVNLALLYPGATLFFQISMSLDVASHWLHLHSSVVRGSESHKMIDLSGNPVLRIYYTSRPALFTLCAGNELFYCLLYLFHFSEGPLVGSVGLFRMGLWVTAPIALLKSLISVIHLITAARNMAALDAADRAKKK------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8SX37-1", "uniprot_id": "CDIPT_DROME", "id": "Q8SX37-1", "name": "CDP-diacylglycerol--inositol 3-phosphatidyltransferase", "aln": "MT------IAEHDNVFIFVPNLIGYARIVLALIAFWFMSTNYVISGWCYVTSALLDAVDGQAARAFNQSTRFGAMLDQLTDRCGTTGLLVTLAYFYPRYMFWFQLSIAIDVACHWLFMQTSVVVGRSSHKVND---NFIMRLYYQ-KDILTFMCCVNELFYVCLYLLHFTYGPLIFGASLFKILAFLTGPFAVLKALISVMHAYVAGIDLAAVDVRERQERRQKSEPVSGKKVE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06197-1", "uniprot_id": "PIS_YEAST", "id": "P06197-1", "name": "CDP-diacylglycerol--inositol 3-phosphatidyltransferase", "aln": "MSSNSTPEKVTAEHVLWYIPNKIGYVRVITAALSFFVMKNHPTAFTWLYSTSCLLDALDGTMARKYNQVSSLGAVLDMVTDRSSTAGLMCFLCVQYPQWCVFFQLMLGLDITSHYMHMYASLSAGKTSHKSVGEGESRLLHLYYTRRDVLFTICAFNELFYAGLYLQLFSN-----SATFGKWTTIISFPGYVFKQTANVVQLKRAALILADNDAKNANEKNKTY---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::: ::** ***.*:: * ::*:.* * * ****.** ** ** : :**:** :***..* *: *. ** . **: :.:*::.*::.: :*: * *** . . ::::** : * :*. ***** *** *: .. : : :: * ::* .*:: *. :* *. : ::. ", "identical_positions": 61, "similar_positions": 64, "identity": "26.07%" }, { "cls_id": "homologset.agr.SGD:S000006318", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CGF5-1", "uniprot_id": "TLCD4_MOUSE", "id": "Q8CGF5-1", "name": "TLC domain-containing protein 4", "aln": "----------------------------MEASTKAAVGSGAMEASTKAVICTVCSSFVVFQILFHFVSYWFSARVSSGYNSLSIDK--------------KIEWNS---------------------RVVSTCHSLLVGIFGLYLFFFDEATIT------DPLWGDPTYVNINIATASGYLISDLL-IILFNWKVIGDKFFIIHHCAG----------------------------------------------------------------LTAYYFVLTTGALAYIAN-------FRLLAELSSPFVNQRWF---FEALKYPKFSKANVINGILMTVVFFIVRIIS-IPPMYFFLYSVYGTEPYIRFGFVIQSVWIVTCVILDVMNIMWMIKITKGCIKVIS-LIRQEKA--------------KDSLQNGKLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AAE5-1", "uniprot_id": "D4AAE5_RAT", "id": "D4AAE5-1", "name": "", "aln": "-----------------------------------------MEANTNVVIGTVCCSFVTFQLLFHFISCWFSARVSLGYNSLSTEK--------------KIEWNS---------------------RVVSTCHSMLVGIFGLYLFFFDEATIA------DPLWGDPSLVKINISTASGYLISDLL-IILFNWKVIGDKFFIIHHCAG----------------------------------------------------------------LIAYYFVLKIGVLAYIAN-------FRLLAELSSPFVNQRWF---FEVLKYPKFSKVNVINGILMTVVFFIVRIIA-IPPMYFYVYSVYGTEPYIRLGSVVHFVWISSCIVLDVMNIMWMIKITKGCMKVIS-LIRQEKA--------------KDSLQNGKLD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96MV1-1", "uniprot_id": "TLCD4_HUMAN", "id": "Q96MV1-1", "name": "TLC domain-containing protein 4", "aln": "-----------------------------------------MEINTKLLISVTCISFFTFQLLFYFVSYWFSAKVSPGFNSLSFKK--------------KIEWNS---------------------RVVSTCHSLVVGIFGLYIFLFDEATKA------DPLWGGPSLANVNIAIASGYLISDLS-IIILYWKVIGDKFFIMHHCAS----------------------------------------------------------------LYAYYLVLKNGVLAYIGN-------FRLLAELSSPFVNQRWF---FEALKYPKFSKAIVINGILMTVVFFIVRIAS-MLPHYGFMYSVYGTEPYIRLGVLIQLSWVISCVVLDVMNVMWMIKISKGCIKVIS-HIRQEKA--------------KNSLQNGKLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XIY2-1", "uniprot_id": "TLC4B_DANRE", "id": "Q5XIY2-1", "name": "TLC domain-containing protein 4-B", "aln": "-----------------------------------------MDMR---EVYVVAGSFVGFQLFFSCVSPVLSSNFTQGYGKLPPNK--------------LNDWNS---------------------RLVSTVHALIVGLFCLYILWYDDAVNE------DPVWGDPNLVKLNVAITCGYLFYDLL-LLACNWSTMGDVFFVCHHLAA----------------------------------------------------------------LYAYGYVLTRGVLPYFAN-------FRLISELSTPFVNQRWF---FEALAYPRTHQLVVANGIAMAVVFFLVRIAV-MPPYWAKVFGIIYSPTFEKLGLAIQVAWIISCVCLDILNIIWMYKIARGCYKVITGKLKGRKADSK-----------KTTCVNNHTD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06107-1", "uniprot_id": "YP114_YEAST", "id": "Q06107-1", "name": "Uncharacterized TLC domain-containing protein YPR114W", "aln": "-----------MDVLLSLPQPELFKTTVIPFLANRNIIKSEAILSNLHSIFYVAIFYHIWFLFGKWILFPHLVKWKLDYDQKHNVK--------------KDEKTTSERQAQHYKKKYTSLINQSSVHLISLLQSIVVLYYSLKFLLDPKASAEPYQTSHSRVFTENRDTQVICIFAIGYFVWDIY-ISTMYSTFP----FVVHGIIS----------------------------------------------------------------TVVFCIGLKP-YIQYYAP-------VFLMFELSNPSLNFRWFGIKFLPQKSKFCSLLLLLNNLTLMVVFFAARIAWGWFQIGKLCYDFYQVRNEPGFLVFDTIVILAGNFVLDILNVIWFSTMVSVAAKVLK---KGESV---------------DKVTKNEQ-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9V3S7-1", "uniprot_id": "Q9V3S7_DROME", "id": "Q9V3S7-1", "name": "TLC domain-containing protein", "aln": "MQQRRQPANGNGRGGGTTAAVRTEEQQQQQQPLSQDAGAKEAGSTPGKATGRGCYFSLAFSIGSMGLACGSLWQIPNSSDRISLQRGLVLTSLGFIYFVSLTDFCNKYLLETTHGQRFRRKYRLMMSDVLEITNKIVSAIQASFSFFVGLIVCKS-TCTKSFVYASHFLMEAYGWFGTAYFMYDIWSMYKVHTQKIADKLHLLRITKGQGAVVSNGHANGKVNGKSASGNNNGSTPTNLHEICDYDGACVQIPKDGRWDFLKYVVTHPVMMIHHVFIGTFGLLVVTYIRGGGHCIYSYMFMMEFSTPFVSLRSI----LSTMRLKDSRVYIANGLLMLATFFVCRVCMWPYVMWRYSLAIEAASLWSAMWGLPRGCLIS-IAILFLPQLYWFYLMVLGALKVFLPQKRRPPNAVLSAKSAAVPTPTPTALINGKN-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : . . . : : . ::. : :: : . :: : .*:. *: : .: : . .: : : * :: *:*.* :. * : : *.: : ..** *: . : : * : :: *: : . **: : :.. ", "identical_positions": 15, "similar_positions": 62, "identity": "3.44%" }, { "cls_id": "homologset.agr.SGD:S000006321", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LSX1-1", "uniprot_id": "F1LSX1_RAT", "id": "F1LSX1-1", "name": "", "aln": "---MPLFVSALLVLLLVALSALFLGRWLVVRLVTRWCQHKLQAELKIGSFRFFWIQNVSLKFQQHQQT-VEIDNLWISSKLLSHDLPHYVALCFGEVRIRTDLQKVS---------------SLSAPFSQNTEVEQKELSLSPSLLKIFCQLFSIHVDAINIMVLKVATSESLWHIQISRSRFLLD----SDGKSLICKVNLSKINSKVLKSGQLEDTCLVELS------LALDLCLQLGIGSWHLKAVTVDVWTLHAELHEGLFHS---QLLCHAPGRISKSVSCSDLTENFAEPTLPG-----LHLLQQLPDRVEVKMENTSVVLSMNSQKRHLTWTLKLLHFLYHRD----EDQLPLRSFTANYDMA-QMSTELLLEDGLLLSQSRQRIVCLN---SLKANVQVTTIDLSASLVLNTCIIHYRHQEFSHWLLMLALETQGASSPD--------------LKQRKKGTFPQILAPVIFS--TSVSNVSISIQLG-DTPPFALGFNSISLDYQHLRPQSIHQR--------AVLTVDHLCWRVGSDSHIQRAPHPPNMHVWGEALVLDSFTLQGSYNQPLGLS--STQSNTLFLDCTIRGLQVEISDICAQCLSRILSLVIPQ--------SEKSAVSRKPSLGECLT-----LLWKVDLKVEDMNLLTLSALVGASEIRLDTLTVLGSAETSTVGIQGLVLALVKSVTEKMQPCCKAPDIPTPVLGLSMLSLTYHSSIRSLEVQCGAGLTLLWSPPDHMYLYQHVLATLQCRDLLRATVFPEIIQSHALKTPQSTSEPEDHLPESSLPRRLLTLTLEVSTAKLTAFVAEDKFITLAAESVSLSRHGGSLQAYCPELAAGFDGNSIFNFKEVEVQLLPELEEMILHRNPFPALQTLRNRVWLLSLGSVSVEFPYQYDFSRTLD-EAVGVQKWLKGLHRGTHAWASPSP----APLPPDLLLKVQHFSWVFLDDIFEVKLHDNYELMKDESKESAKRLQLLDAKVA-------ALRKQHGELLPARKIEELYASLERKNIEIYIQRSRRLYGNTPMRRALLTWSLTGLELVALADASFHGPERVIEQVRELDPG-------------SPFPAE---------------GMDLVIQWCRMLKCNVKTFLVRIRDYPRYLFEIRDWRLVGRLAGTEQSGQPCSRRRQILHLGLPWG-----------NVAVERNMPPLKFYHDFHSEIFQYT---VVWGPCWDPAWTLIGQCVDLLTKPSADPSPPLPWWDKSRLLFHGDWHMDIEQAN---LHQLATEDPYNTTEN---MHWEWSHLSFHWKPGQFVFKGDLDVNVR----------TASKYDDCCFLHLPDLCMTLDLQWLC--HGNPHDHHSVTLRAPEFLPEVPLGQ------LHDSYRAFRSENLNLSIKMDLTRHSGT---ISQPRILLYSSTLRWMQNFWATWTSITR-PICRGKLFNNLKPSKKKLGQHYKQLSYTALFPQLQVHYWASFAQQR--------------GIQIECSQGHVFTRGTQRLIPQAGTVMRRLISEWSVTQMVSDLSQVTVHLMASPTEEN-------ADHCLDPLITKTHLLSLSSLTYQRHSNRTTEEELSARDG--DAAFHTHQLYLVDLRISWTTTNRDIAFGLYDGYKKAAVLKRNLSTEALKGLKIDPQMSAKKPKRG-------IPPRAQAQPRASAPSFRGRPDKGSSGGAYMLQKLIEETDR-FVVFTEEESGMS--DQLCG------IAACQTDDIYNRNCLIELVNCQMVLRGAETEGCVIVSAAKAQLLQCQHHPAWYGD------------TLKQKTSWTCLLDGMQYFATTESSPTE--QDGRQLWLEVKNIEEHRE---RSLDSVQELMESGQAVGGMVTTTT--DWNQPAEAQQAQQVQRIISRCNCRMYYISYSHDIDPELATQIKPPE-------VHENQEKEDLLKKQEGAVDTFTLIHHELEISTN------------------------------PAQYAMILDIVNNLLLHVEP-----KRKEHSEKKQRVRFQLEISSNPEEQRSSILHLQEAVRQHVAQIR-HLEKQMYSIMKSLQDDNKNENLLDVNQKLQLQLNQEKANLQLE-----------------SEELNILIRCFKDFQLQRANKMELRKQQEDVSVVRR---TEFYFAQARWRLTEEDGQLGIAELELQRFLYSKVNKSDDTAEHLLELGWFTMNNLLPNAIYKVVLRPQSSCQSG----RQLALRLFSKVRPPVGGISVKEHFEVNVVPLTIQLSHRFFHRMMGFFFPGRNVEDDEVGD-EEDKSKLVTTGIPVVKPRQLIATDDAVPLGSGKGVAQGLSRSSGVRRSFRKLP-----------EHPVDDIDKMKERAAMNNSFIYIKIPQVPLCVSYKG--EKNSVDWGDLNLVLPCLEYHNNTWTWLDFAMAVKRDSRKALVAQV--IKEKLRLKPATGSEVRGKLETKCDLNMQQQEEE-KARLLIG----LSVGDKNPGKKSIFGRRK-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SYL3-1", "uniprot_id": "BLTP2_MOUSE", "id": "Q5SYL3-1", "name": "Bridge-like lipid transfer protein family member 2", "aln": "---MPLFLSALLVLLLVALSALFLGRWLVVRLATRWCQRKLQAELKIGSFRFFWIQNVSLKFQQHQQT-VEIDNLWISSKLLSHDLPNYVALCFGEVRIRTDLQKVS---------------SLSAPFSQNTEVEQKELSLSPSLLKIFCQLFSIHVDAINIMVLKVATSESLWHIQISRSRFLLD----SDGKSLICKVNLSKINSKVLKSGQLEDTCLVELS------LALDLRLQVSVSSWHLTAVTVDVWTLHAELHEGLFHS---QLLCHAPGRISKSVSCSDLTENFAEPTLPG-----LYLLQRLPDQVKVKMENTSVVLSMNSQKRHLTWTLKLLHFLYHRD----EDQLPLRSFTANYDMA-QMSTELLLEDGLLLSQSRQRIVCLN---SLKANVQVTTIDLSASLVLNTCIIHYRHQEFSHWLLMLALETQGASSPD--------------LKQRKKRTFPQILAPIIFS--TSVSNVSISIQLG-DTPPFALGFNSISLDYQHLRPQSIHQR--------AVLTVDHLCWRVGSDSHIQRAPHPPNMHVWGEALVLDSFTLQGSYNQPLGLS--STQSNTLFLDCTIRGLQVEISDICAQCLSRVLSLVIPQ--------SERSAVSRKSSLGESVT-----LLWKVDLKVEDMNLFTLSALVGASELRLDTLTVLGSAETSTVGIQGLVLALVKSVTEKMQPCCKAPDIPTPVLGLSMLSLTYHSSIRSLEVQCGAGLTLLWSPPDHMYLYQHVRATLQCRDLLRATVFPEIIESHSLNTPQSTWEPEDHLPESSLPRRLLTLTLEVSTAKLTAFVAEDKFITLAAESVSLNRHGGSLQAYCPELAAGFDGNSIFNLKEVEVQLLPELEEMILHRNPFPALQTLRNRVWLLSLGSVSVEFPYQYDFSRTLD-EAVGVQKWLKGLHRGTHAWASPSP----APLPPDLLLKVQHFSWVFLDDIFEVKLHDNYELMKDESKESAKRLQLLDAKVA-------ALRKQHGELLPARKIEELYASLERKNIEIYIQRSRRLYGNTPMRRALLTWSLAGLELVALADASFHGPEHVIEQVRELDPG-------------SPFPAE---------------GMDLVTQWCRMLKCNVKTFLVRIRDYPRYLFEIRDWRLMGRLAGTEQSGQPCSRRRQILHLGLPWG-----------NVAVERNMPPLKFYHDFHSEIFQYT---VVWGPCWDPAWTLIGQCVDLLTKPSADPSPPLPWWDKSRLLFHGDWHMDIEQAN---LHQLATEDPYNTTEN---MHWEWSHLSFHWKPGQFVFRGDLDVNVR----------TASKYDDCCFLHLPDLCMTLDLQWLC--HGNPHDHHSVTLRAPEFLPEVPLGQ------LHDSYRAFRSENLNLSIKMDLTRHSGT---ISQPRILVYSSTLRWMQNFWATWTSITR-PICRGKLFNNLKPSKKKLGQHYKQLSYTALFPQLQVHYWASFAQQR--------------GIQIECSQGHVFTRGTQRLIPQAGTVMRRLISEWSVTQMVSDLSQVTVHLMASPTEEN-------ADHCLDPLITKTHLLSLSSLTYQRHSNRTTEEELSARDG--DPAFHTHQLYLVDLRISWTTTNRDIAFGLYDGYKKAAVLKRNLSTEALKGLKIDPQMSAKKPKRG-------IPPSAQVPPHVSTPSFSGRPDKGSSGGAYMLQKLIEETDR-FVVFTEEESGMS--DQLCG------IAACQTDDIYNRNCLIELVNCQMVLRGAETEGCVIVSAAKAQLLQCQHHPAWYGD------------TLKQKTSWTCLLDGMQYFATTESSPTE--QDGRQLWLEVKNIEEHRE---RSLDSVQELMESGQAVGGMVTTTT--DWNQPAEAQQAQQVQRIISRCNCRMYYISYSHDIDPELATQIKPPE-------VHENQEKEDLLKKQEGAVDTFTLIHHELEISTN------------------------------PAQYAMILDIVNNLLLHVEP-----KRKEHSEKKQRVRFQLEISSNPEEQRSSILHLQEAVRQHVAQIR-HLEKQMYSIMKSLQDDSKNENLLDLNQKLQLQLNQEKANLQLE-----------------SEELNILIRCFKDFQLQRANKMELRKQQEDVSVVRR---TEFYFAQARWRLTEEDGQLGIAELELQRFLYSKVNKSDDTAEHLLELGWFTMNNLLPNAIYKVVLRPQSSCQSG----RQLALRLFSKVRPPVGGISVKEHFEVNVVPLTIQLSHRFFHRMMGFFFPGRNVEDDEVGD-EEDKSKLVTTGIPVVKPRQLIATDDAVPLGSGKGVAQGLTRSSGVRRSFRKLP-----------EHPVDDIDKMKERAAMNNSFIYIKIPQVPLCVSYKG--EKNSVDWGDLNLVLPCLEYHNNTWTWLDFAMAVKRDSRKALVAQV--IKEKLRLKPATGSEVRGKLETKCDLNMQQQEEE-KARLLIG----LSVGDKNPGKKSIFGRRK-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14667-1", "uniprot_id": "BLTP2_HUMAN", "id": "Q14667-1", "name": "Bridge-like lipid transfer protein family member 2", "aln": "---MPLFFSALLVLLLVALSALFLGRWLVVRLATKWCQRKLQAELKIGSFRFFWIQNVSLKFQQHQQT-VEIDNLWISSKLLSHDLPHYVALCFGEVRIRTDLQKVS---------------DLSAPFSQSAGVDQKELSFSPSLLKIFCQLFSIHVDAINIMVLKVDTSESLWHIQISRSRFLLD----SDGKRLICEVSLCKINSKVLKSGQLEDTCLVELS------LALDLCLKVGISSRHLTAITVDVWTLHAELHEGLFQS---QLLCQGPSLASKPVPCSEVTENLVEPTLPG-----LFLLQQLPDQVKVKMENTSVVLSMNSQKRHLTWTLKLLQFLYHRD----EDQLPLRSFTANSDMA-QMSTELLLEDGLLLSQSRQRIVCLN---SLKASVQVTTIDLSASLVLNTCIIHYRHQEFSHWLHLLALETQGSSSPV--------------LKQRKKRTFPQILAPIIFS--TSISNVNISIQLG-DTPPFALGFNSISLDYQHLRPQSIHQR--------GVLTVDHLCWRVGSDSHIQRAPHPPNMHVWGEALVLDSFTLQGSYNQPLGLS--STQSDTLFLDCTIRGLQVEASDTCAQCLSRILSLMGPQ--------SGKSAVSRHSSFGESVS-----LLWKVDLKVEDMNLFTLSALVGASEVRLDTLTILGSAETSTVGIQGLVLALVKSVTEKMQPCCKAPDIPTPVLSLSMLSITYHSSIRSLEVQCGAGLTLLWSPPDHMYLYQHVLATLQCRDLLRATVFPETVPSLALETSGTTSELEGRAPEPLPPKRLLNLTLEVSTAKLTAFVAEDKFITLAAESVSLSRHGGSLQAYCPELAAGFDGNSIFNFKEVEVQLLPELEEMILHRNPFPALQTLRNRVWLLSFGSVSVEFPYQYDFSRTLD-EAVGVQKWLKGLHQGTRAWASPSP----VPLPPDLLLKVEHFSWVFLDDVFEVKLHDNYELMKDESKESAKRLQLLDAKVA-------ALRKQHGELLPARKIEELYASLERKNIEIYIQRSRRLYGNTPMRRALLTWSLAGLELVALADASFHGPEHVVEQVQELDPG-------------SPFPPE---------------GLDLVIQWCRMLKCNVKSFLVRIRDYPRYLFEIRDWRLMGRLVGTEQSGQPCSRRRQILHLGLPWG-----------NVAVERNMPPLKFYHDFHSEIFQYT---VVWGPCWDPAWTLIGQCVDLLTKPSADPSPPLPWWDKSRLLFHGDWHMDIEQAN---LHQLATEDPYNTTEN---MHWEWSHLSFHWKPGQFVFKGDLDINVR----------TASKYDDCCFLHLPDLCMTLDLQWLC--HGNPHDHHSVTLRAPEFLPEVPLGQ------LHDSYRAFRSENLNLSIKMDLTRHSGT---ISQPRILLYSSTLRWMQNFWATWTSVTR-PICRGKLFNNLKPSKKKLGQHYKQLSYTALFPQLQVHYWASFAQQR--------------GIQIECSQGHVFTRGTQRLIPQAGTVMRRLISDWSVTQMVSDLSQVTVHLMASPTEEN-------ADHCLDPLVTKTHLLSLSSLTYQRHSNRTAEEELSARDG--DPTFHTHQLHLVDLRISWTTTNRDIAFGLYDGYKKAAVLKRNLSTEALKGLKIDPQMPAKKPKRG-------VPTSASAPPRVNTPSFSGQPDKGSSGGAYMLQKLIEETDR-FVVFTEEESGMS--DQLCG------IAACQTDDIYNRNCLIELVNCQMVLRGAETEGCVIVSAAKAQLLQCQHHPAWYGD------------TLKQKTSWTCLLDGMQYFATTESSPTE--QDGRQLWLEVKNIEEHRQ---RSLDSVQELMESGQAVGGMVTTTT--DWNQPAEAQQAQQVQRIISRCNCRMYYISYSHDIDPELATQIKPPE-------VLENQEKEDLLKKQEGAVDTFTLIHHELEISTN------------------------------PAQYAMILDIVNNLLLHVEP-----KRKEHSEKKQRVRFQLEISSNPEEQRSSILHLQEAVRQHVAQIR-QLEKQMYSIMKSLQDDSKNENLLDLNQKLQLQLNQEKANLQLE-----------------SEELNILIRCFKDFQLQRANKMELRKQQEDVSVVRR---TEFYFAQARWRLTEEDGQLGIAELELQRFLYSKVNKSDDTAEHLLELGWFTMNNLLPNAVYKVVLRPQSSCQSG----RQLALRLFSKVRPPVGGISVKEHFEVNVVPLTIQLTHQFFHRMMGFFFPGRSVEDDEVGD-EEDKSKLVTTGIPVVKPRQLIATDDAVPLGPGKGVAQGLTRSSGVRRSFRKSP-----------EHPVDDIDKMKERAAMNNSFIYIKIPQVPLCVSYKG--EKNSVDWGDLNLVLPCLEYHNNTWTWLDFAMAVKRDSRKALVAQV--IKEKLRLKSATGSEVRGKLETKSDLNMQQQEEEEKARLLIG----LSVGDKNPGKKSIFGRRK-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZS7-1", "uniprot_id": "HOBIT_DROME", "id": "Q9VZS7-1", "name": "Protein hobbit", "aln": "---------MMLQLLLFCLALFIFVYWVLPTGISWYLVKRFRVKVRIGRISLPYLSLKNVHISKSGFS-VQIEEVCLRSSFFTTEVTKLLSIYIRDIRINKDIHSRQDDSYDQDSYELRRTQTLAGKASEAKGVPDFRQTKVPASIITFAQFMAVHVNNISVVLMNNDFDP-GWFIHATAKELHLDGSIVQNARVLLVNAALSEAQAKMLRHCSSRRQSLENLNKIRPCLGEVSFDMTLDASLFAQGPLSMDTLSLVINNAKSVIHGGLYEFLSEAKRRTSTGQPSRRSTQGLAPSKRSYDNDNYEKLAPIIPKNFNFSIKAATFSAVKENSQNDFSAKLQSFQISGKFNSKVTDEKTLLPSMLAKLGFH-HLDIDTKYEKLLFVEQFTIDSVLEKDIFNLYVKLKTFQIIYNHSEIYDFVNNNFLARQRSSEAQPMQLIHKQKSLPDHLDLDTAVQSNLRANQRREGGVLEWIMQRIVVKGCAELFNVSLLMKLEDEHIAMSVSHTRFLLEQIEEKRSNLYEN--------KFLNLLLNQRQWSMELMVETLWSNLGNSINDTNNLKKTHSPGSPFFLGVSLVKLCSYANTTKLDISVHTFRTEYSMQLAEFVVKSMECLRQYRGIKPKNMSGQSHARPNAGLTLSVQPSQSSTSLRVSVKVKDITAYFVNHHNVYSLLSFSELNLSRSQSLTTLKLEEFQMAIMRSMTASSLCLTDFSDVFATCKMIRLEHEQVEGTMGKLSIYIPGNMEATWNSNLHMHLLTLVRDMQDLKTELAIPAS-----------SVKKTTPKEGFIVELSAERSTIFEIKFSDRHSIQIFVESLFFSQKERCIIYAEN----------VFVKIDDQHIFTVKELDLQSVPRLEVLTQERQNFPGFQLPSNKVWVTTIGSFKAIFPYDHDFYNAVNGECTSHFKWLKMVHN-YKKKPFTVD----SPLPCDLVIKIKEFLLEISDDPFEVKLRDNYVLLVDEYLESLKRKALFDKKIG-------ELCSER-LLLPSGTIEGLYANLVKKNSEIYIQRSKKIRESGPVRTRLLAWIMTDVNIMAMADTSIHGYNNVTRIMREIDHE-------------SPWPEE---------------GLEFSTLWCRGVNISCTEWKFMLRDFPQPMFCVKSMRLYGNLCGAEQMGSKRAKRDVFIDVGEPFG-----------TDVIQRSMPSLKFYHDFDCELESCS---YAFGACWEPVMAQCNLSFEKISAPSKDPSPPLPFWDKLRLLLHGRLTLIAKQFT---ILLHASLDPYNTTEE---MELTWNNCGIVLTNAKIMFKGELNVTVR----------TASRYDDCRLLHFPNLKLTIKLKWVC--LANPNDHHAVMPCAPDKLPEYSSNQ------VHDSFRAFRSLNLNIWISFETKPKAGEDLEVDIPSLVLYGSTLRWFESLQLILSGVTR-PTRRGPVFNNVRPRKKPLSRHYKKANLQMCLHKFQVLYWMSHALQK--------------GFQLNGRRVSFSSEHSLTLNPIDDGLIHRPRADWSTIYMNCELNDAEIWLKSILTEKMDSSSENLASAADAFKIVRFYFLSVAKVSYGREALIPTTATSTEEDVKAQSTTPTHKLVVYDLKGAWTKSNRDVAFALFDSFMKSQKLKNNLSTEAVKSYRKEGPNSAVLKHKRS-DSTITLSSTNNEVLPISNPNASMKKAPAQIHATAMLQQLIAEADHKFNVYSDDHSTQSRELQLQG------LQACSAQDIIHENWSISLVNSQVLLKGCETSGYVIISAAKAEILQREHRPVWRER------------SLISKTTWKGLLECMQYYATVSAGDNNSLLEKEIMWLTVDNIQDKDETVINNLPDISHLVGSGRSVGGVVSETVGAFLSDNSGGAQPVQLQRIVSKCKCEFFYVSYGDAIDPNSITEVPPP----------PSEELQSPWEKQDDPVDAFTLMHHDLDVCTN------------------------------SLQYAMILDIVNNLLLYVEP-----QRKQAAEKLTRMRFQLQLHS-TEDQKRPIQQKQTVIRSLLMKIR-SLEKDTHMISKERIEDGDSLELRQEYDHVQQMIRESKEELNTF-----------------SEDLDMMLLCYKETQLSQLSKISNVRSDESVTMVRT---NEICFKRAQWRLTETDGQIGIADLVLSAFLYTKKSKSDDSVEHLLELGNIRMENLLPREIYRDVLLATEIQKDMPVDTHKRVLRIFCREKAPVGGISVKEHFEINVAPITIAITKKFYSTMLKFCFPDRDASETEVSD-ELDDNASTSSASTTNLQAKSSTSSSTKRSGKGKKGAKDSEFYVKIEK---------------------DDVEKMKERAEKNKLFIYIKIPEVPVRVSYKGNKEKNLEDITDYSLVIPTLEYHNVTWTWLDLLLAMKSVSRRVIFSQA--IKQKLHIHQRQ------PILSAGERATPQEAEDKAVMLFGN----RLLNENRNQKKGVFKFASSGKRSGND---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06116-1", "uniprot_id": "HOB2_YEAST", "id": "Q06116-1", "name": "Protein YPR117W", "aln": "MSMLPWSQIRDVSKLLLGFMLFIISIQKIASILMSWILMLRHSTIRKISFGYFFGTSIRRAFILTDFAQIYIGKITLRIGWKPGIVFHNVDLKLFGKDSHITAHSTK-----------------DSRTYFNPRDQTFTFVINRRVLSILKLVFSFSTFFHTLALTVPNGKQYKLNIGSITISHPHDDT--IKLEAFLHDFTHPETKDTLNHTGFFMVCKIGKEDD-----TGSNCTKVILKNWKSSLKISDVCWHLPEKKGKNLHSEPVEPFSAGDDAEMLTSYRKMLKPFHYPLKTLNILDLKVENVKLIYKKKFTIRISSAQLYLESISILNNVSALELLPLNKPTWG----DFELSLSANAVVVDIDGNTAVRIPFGNVILTSDILLFLLDNVPLRRTKVSSILNIINPSVFLTIHQVLEVLHLVDKFDSPETSSCTNTNDRSLN--------------ILDLDIDRLPSFNFELLMSNFISRLHISDEENVTFKVFSTHALFSRNNLSMTPKKGQVMQIRPDWPFAKTALVSDQLSNYIKIVGTSLSYLRIPTEQDANPVSIPVCGFERLDTFLDEFSNS--KLIVQSTLRHSYVSLENIEVLHTLSRAFDKIYLLISSR-------TKRNAAHKANGGKLGDLNEAKKTFNWSLKLRMKDISCSLLVAGFLPKNLDPVEAENFNLSDVTRGAKVVFTESILLADSQEKNFTIIDASVYR-----FMDGTTYKPSPEVIIQFTNLLLSFNDSDEIHFSLPKIKFKMDVNIIWLWFYIR----------SIWIKFRPNSKLSRNSVSSVKSVNVLDRLRVDIGKMIIELTLPHNTEVLLIFERIG--LSSSTKNLTIASLSAYVVSVYVKHIKVYVSLLNINDFELDTEELICKKSAVINTSLIHFHAEYHFRFYMITDNIVTLYKSFKQIKLAFSNLNEFKRLYPQQQFPKKVPNLHICCQDFLIDIEEDPFEQELGLILKVGVLEQRERLKKLEEFKEKLSTYEDMNVRLRSLYDTSRGQSFFPEFYANDQEYEQKAYLRLLENFSTSWIARYRKAKLSFYGMPYRVISREELGTKYHLFTRQKTSTVANLVVKDLDFKLGSPSFPLDNYMDFVYQYGKKVPKSTEYTLLIILGLKIKSALWELRLRDYPIPAISFPDTFTTGDVVFAEKMPAPCALHTVYVPFVSSAQRSPYNDANTIYGLHIIRTINSVKTYFNIRSMVTSSSSARITWGKSLQPGYESLMLWFDFLTKPLIDPSKKLGFWDKFRYLVHGKWIYEFSEESEIHLNIKGSHDPYKITDDGAGLAFCWSGGTTIYVHNSTDPKEFLKIESQRFQLAVPDFAKVSKFDKVFMKLDGRVIWTLGLLFEQGDISKAGDEERFLPNRPHYEIQLMNPDGVADLDHHDTYKGFRTSFIHMSFGVYSSEHGSIN------SLYLAPYALTHFFKWWNLFHTYTSGPIRQGRLFTDVLQNKTKFGRSLFTIAYQLHLKRLMVTHIYRHITTQYDLEKDRKITFTGLKGRFDSLKIDLHQKRVKLTHTNQKLNKSKPVWKFKMSRGEIDCAEADIRILSTLFDQEAVKEILTSGLDGILEDEPSRPITPQDVEYLRESDWYDYEDYIDLNQ--VPLGSSLPLKLEAIPLLYSPRISYFRKINDDGYVLAYPFGTEESHNCLIGKNHPELTQEKLATERKREIEEQLKLLHITLSELQSNKGGGSVSGNSERYARELKAEVAELNHRLHTVNTILSDLKISETIPGGNTDGDSSSSLSDTDVNLENAPPIQNRISLLRTNTVESFVSMRKASTMQVESTYDNRFMVHNIELKIDNKIRHHLLEYASSAFERKSMRFAVTYKSVTILKELLGNVLTGVRTSVEDYGSILEDDLASNSEFIEHFEKLIREVPSDD-FDYVDNYLFRLISPQVQIKSDVERNAAVILAARDIEMGIIDIVQVYGKSGKRIPVDVDTIVETRYSAVSKDIQLFTLFKKDLEGPEGRFFHKNGYGSDKESDIWPPWIPLEMCFDGSLLDKHVFLKRRSMFLTYVAPNPLFFSANDTSAFSYDSRFRIAFPGLVLTSDCQQYCAVYAIAEDLLSFGSSLDEKVEKLSRILFTDEVRNNLENLDVSVVTALQERIKELYYTRAYLKLHEPRLFMKSGQELTFDIQTSTLKLTLLMTAIKKTYDRMGSGNRVIQKRLRWQVGTDELIWELYD-ESKTPFVTIGLGPSTFIRSETSDGTNSNKVSISSLQCFNQQENPVYTELLAPFYENSSYN--KNAPMVEIFWILGPSVGGISDLQDLIVSLQPLIFKMDHKTSEKLMNYLFPKIEQTSIEPNSPELVPRSSTSSFFSSSPVLRHSLSNGSLSVYDAKDVDSWDLRSIQSKEGIKKHKGDHRKLSASLFVQPDYNINEMVKRSGTFFNVKSIIIRKTLMSVCYKG-SHSLLTDVNNLIVRVPVLKYHNKLWSREEFFTALKRDVVRIVLQHLGNIIGNKFLPHKKENKKKTSMEIHRLLSPDSQNRDNSHILEVEGHNSFYSSTHSSDIRSINSDETYNENDGNGVKPFYPVTSEFSKNK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **. : ::: : : : :: : : : : : * :: : . : : : : : . :. . . : : .::. . .: : . * * . . :: . : : .: : : : . . : . :: * : :.: : . . . . : ... . :. : . . ...: . : : * : . .: : . :: .: : .. * . . : . : : ::.. . ::. :: . . .. *. : . : . .:. :. . ..: .. :: . : . * :. . : : . .: : . : :.::::*:. : . : . : : ::: : : . ..: : . : : : . *: * * . : . :. . :. * : : . : . :... .:: * : . : . * :: . . : : . : * :* . . :* : :.* : :* ** :* : * * *: :. *:. * . : :**. . : : *:: ..: . * : .: .:: .: .: : ..:* : . : :: . : . :**:* : . . * : :*: : : : . . : *.: .:* *.:: . : . : .:* . :* .: :: * *** * :*** * *.** .: . : .: ***: *:: : *. . : *.: : ..*::*. : : *: * : .:. *.. . *. : : **:::.**: ::: : . . :.. : : :* : . * * :* :*.:: *. :.: : :: * : . : ::: : . . . : .:. : :. : : : :: :. :: .: * *.: : . : * : : :: . *.: : : : * :.: . . . : . . . : *: : * :: : . . * . : * :. :: : : : * :*: ... * : *.: :: : : * . :: . *:: .* .: . : .::: . .* . ..:: . : *. : :* * : . : . *: : . : . . :: ***::::*: . : ::*. . :* :* * . :: : **:: : . . .: . : .: *::. : : * :* : : :.: :* . ::: * * * : .. ::: :. . *.* : :.: :. : * : : ..**.: .: :.:. : * . :* :* . .. . :.:* ..***** :.: :.: *: : : :: :: : ** . . * .. * .:: . : :..: .* . .. ::::* :*: . * * :. : *.*** .. * : : :* *:*** *: :: *:* : :. : * : : : .: .: * . : :.: . ", "identical_positions": 157, "similar_positions": 639, "identity": "6.11%" }, { "cls_id": "homologset.agr.SGD:S000006322", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5HZE4-1", "uniprot_id": "MTNA_RAT", "id": "Q5HZE4-1", "name": "Methylthioribose-1-phosphate isomerase", "aln": "MRLEAIRYSPG-----SLQILDQLQLPEHCHYETLSSVQQAREAIRAMKVRGAPAIALVGCLSLAVELQAGAGGP-----------GLAALVAFVRDQLSLLVAARPTAVNMARAARDLTHMAAREAELEGATEETVRERVIRFAEDMLEKDLKDNRSIGDLGARHLLEQTNPR-------GGKVTVLTHCNTGALATAGYGTALGVIRSLHEMG-----------------RLEHTFCTETRPYNQGARLTAFELVYEKIPATLITDSMAAAAMVHQ--GVSAVVVGADRVVANGDTANKIGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIVIEERPSQELTDLNG----------------------VRIAAQGIRVWNPAFDVTPHELITGGIITELGVFAPEELRAALSATIFSEGQTLDSPQM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQT1-1", "uniprot_id": "MTNA_MOUSE", "id": "Q9CQT1-1", "name": "Methylthioribose-1-phosphate isomerase", "aln": "MTLEAIRYSPG-----SLQILDQLQLPEHCHYEALSSVQQASEAIRAMKVRGAPAIALVGCLSLAVELRAGAGGP-----------GLAALVAFVRDQLRLLVAARPTAVNMARAARDLGQVAAQEAEREGATEETVRERVIRFAEDMLEKDLKDNRSIGDLGARHLLEQTNPR-------GGKVTVLTHCNTGALATAGYGTALGVIRSLHEMG-----------------RLEHTFCTETRPYNQGARLTAFELVYEQIPATLITDSMAAAAMAHR--GVSAVVVGADRVVANGDTANKIGTYQLAIVAKHHGVPFYVAAPSSSCDLHLETGKEIVIEERPSQELTDLNG----------------------VRIAAQGIRVWNPAFDVTPHELITGGIITELGVFAPEELRGALSASVFSEGQTLDSPWV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BV20-1", "uniprot_id": "MTNA_HUMAN", "id": "Q9BV20-1", "name": "Methylthioribose-1-phosphate isomerase", "aln": "MTLEAIRYSRG-----SLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLAVELQAGAGGP-----------GLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEAVRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPS-------GGKVTVLTHCNTGALATAGYGTALGVIRSLHSLG-----------------RLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHR--GVSAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQELTDVNG----------------------VRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEELRTALTTTISSRDGTLDGPQM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A9JRE2-1", "uniprot_id": "MTNA_DANRE", "id": "A9JRE2-1", "name": "Methylthioribose-1-phosphate isomerase", "aln": "MTLEAIRYRSG-----SLQILNQLLLPRETVYDEIRSVRDGYEAIKSMKVRGAPAIAIVGCLSLAVELRAGAG--------------AEDLVSFVRDSLCHLTSARPTAVNMGRAARELMEFTENES--MEKNTEQLRDSVIGWIEEMLERDVNDNKKIGNYGAQHILSGVP---------RDSVTILTHCNTGSLATAGYGTALGVVRSLHMLG-----------------RLKRLYCTETRPYNQGARLTAYEAVAEGFPATLITDSMAALAMREK--SITAVVVGADRVVANGDTANKVGTYQLAIAAKHHGIPFYVAAPSTSCDLSLESGRDIVIEERPAEELTSING----------------------VPVAAPGIDVWNPAFDVTPHQLITGGIITELGVFLPSELQAALTGRLTAL---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V9X4-1", "uniprot_id": "MTNA_DROME", "id": "Q9V9X4-1", "name": "Methylthioribose-1-phosphate isomerase 1", "aln": "MSLQSIKYSRG-----SLEILDQLLLPGQSKYVVVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVEINPEDFE------------NKKSLRQEIEGKLNYLVSARPTAVNMKIAADELITLANELYKDEAIDVTQMKHRFLDATEAMLKKDIADNRAIGANGAQAILQGVAKAGKAPAGSTGSVRVLTHCNTGSLATAGYGTALGVVRQLAELG-----------------KLEHVYCTETRPYNQGARLTAYELVHEKFPATLVLDSMVAALLRAK--NVAAVVVGADRVASNGDTANKIGTYQIAVVAKHHDVPFYVAAPLTSIDLAIPGGDHIIIEERPDREMTHVGE----------------------HRIAAPGINCWNPAFDVTPASLITG-IITERGVFKPAELKEAITKLLES----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06489-1", "uniprot_id": "MTNA_YEAST", "id": "Q06489-1", "name": "Methylthioribose-1-phosphate isomerase", "aln": "MSLEAIVFDRSEPENVSVKVLDQLLLPYTTKYVPIHTIDDGYSVIKSMQVRGAPAIAIVGSLSVLTEVQLIKHNPTSDVATLYSLVNWESTKTVLNKRLDFLLSSRPTAVNLSNSLVEIKNILKSSS-----DLKAFDGSLYNYVCELIDEDLANNMKMGDNGAKYLIDVLQKDG-----FKDEFAVLTICNTGSLATSGYGTALGVIRSLWKDSLAKTDKADSGLDNEKCPRMGHVFPLETRPYNQGSRLTAYELVYDKIPSTLITDSSIAYRIRTSPIPIKAAFVGADRIVRNGDTANKIGTLQLAVICKQFGIKFFVVAPKTTIDNVTETGDDIIVEERNPEEFKVVTGTVINPENGSLILNESGEPITGKVGIAPLEINVWNPAFDITPHELIDG-IITEEGVFTKNSSGEFQLESLF-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *::* : . *:::*:** ** * : : :. ..*. *:********:**.**: .*:. :. * * ::******: : :: . . . ::..*: :* :* **: ::. ... :** ****:***:********:*.* . :: : : ********:****:* * : :*:**: ** * : : *..*****:. *******:** *:*: .*:..: *:*.** :: * * .*::*** .*:. : :*. * ******:** .** * **** *** . : ", "identical_positions": 126, "similar_positions": 94, "identity": "29.1%" }, { "cls_id": "homologset.agr.SGD:S000006323", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24860-1", "uniprot_id": "CCNB1_MOUSE", "id": "P24860-1", "name": "G2/mitotic-specific cyclin-B1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALRVTRNTKINAENKAKVSMAGAKRVPVTVTAASKPGLRPRTALGDIG----------------------------------NKVSEELQARVPLKRE----------------------------AKTLGTGKGTVKALPKPVEKVPVCEPEVELA---------------------------------------EPEPEPELEHVREEKLSPEPILVDNPSPSPMETSG----------CAPAEEYLCQAFSDV-----------ILA-VSDVDADDGADPNLCSEYVKDIYAYLRQLE-EEQSVRPKYLQGREVTGNMRAILIDWLIQVQMKFRLLQETMYMTVSIIDRFMQNSCVPKK-MLQLVGVTAMFIASKYEEMYPPEIGDFAFVTNNTYTKHQIRQMEMKILRVLNFSLGRPLPLHFLRRASKVGEVDVEQHTLAKYLMELSMLDYDMVHFAPSQIAAGAFCLALKILD----------NGEWTPTLQHYLS-YSEDSLLPVMQHLAKNVVMVNCGLTKHMTVKNKYAASKHAKISTLAQLNCTLVQNLSKAVTKA-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30277-1", "uniprot_id": "CCNB1_RAT", "id": "P30277-1", "name": "G2/mitotic-specific cyclin-B1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALRVTRNTKINTENKAKVSMAGAKRVPVAV-AASKPLLRSRTALGDIG----------------------------------NKVSE--QSRIPLKKE----------------------------TKKLGSGTVTVKALPKPVDKVPVCEPEVELD---------------------------------------EPEPEP----VMEVKHSPEPILVDTPSPSPMETSG----------CAPAEEYLCQAFSDV-----------ILA-VSDVDADDGGDPNLCSEYVKDIYAYLRQLE-EEQSVRPKYLLGREVTGNMRAILIDWLIQVQMKFRLLQETMYMTVSIIDRFMQDSCVPKK-MLQLVGVTAMFIASKYEEMYPPEIGDFAFVTNNTYTKHQIRQMEMKILRVLNFSLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELSMLDYDMVHFAPSQIAAGAFCLALKILD----------NGEWTPTLQHYLS-HTEESLLPVMQHLAKNIVMVNRGLTKHMTIKNKYATSKHAKISTLAQLNCTLVQNLSKAVTKA-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14635-1", "uniprot_id": "CCNB1_HUMAN", "id": "P14635-1", "name": "G2/mitotic-specific cyclin-B1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIG----------------------------------NKVSEQLQAKMPMKKE----------------------------AKPSATGKVIDKKLPKPLEKVPMLVPVPVSEP------------------------------------VPEPEPEPEPEPVKEEKLSPEPILVDTASPSPMETSG----------CAPAEEDLCQAFSDV-----------ILA-VNDVDAEDGADPNLCSEYVKDIYAYLRQLE-EEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKK-MLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILD----------NGEWTPTLQHYLS-YTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNSALVQDLAKAVAKV-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5M857-1", "uniprot_id": "Q5M857_RAT", "id": "Q5M857-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALLRRPTVSSDLKNIDTGVNPKAK---------SHVTVR-RAVLEEIG----------------------------------NKVRAR-PAQVAKKPQ----------------------------NTKVPVQPTKAINASK------------------------------------------------------QPKPTASVKPVQMETLAPK-----DPLPAPEDVS-------------MKEESLCQAFSDA-----------LLCKIEDIDNEDGENPQLCSDYVKDIYQYLRQLEQALQSINPHFLDGRDINGRMRAILVDWLVQVHSKFRLLQETLYMCIAIMDRFLQAQPVCRK-KLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLVDYDMVHYHPSQVAAAASCLSQKVLG----------QGKWNLKQQYYTG-YMESEILEVMQHMAKNVVKVNENLTKFIAVKNKYASSRLLKISTIPQLNSRTIKDLASPLMGRP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6A3R0-1", "uniprot_id": "A0A8I6A3R0_RAT", "id": "A0A8I6A3R0-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALLRRPTVSSDLKNIDTGVNPKAK---------SHVTVR-RAVLEEIG----------------------------------NKVRAR-PAQVAKKPQ----------------------------NTKVPVQPTKAINASK------------------------------------------------------QPKPTASVKPVQMETLAPK-----DPLPAPEDVS-------------MKEESLCQAFSDA-----------LLCKIEDIDNEDGENPQLCSDYVKDIYQYLRQLE-ALQSINPHFLDGRDINGRMRAILVDWLVQVHSKFRLLQETLYMCIAIMDRFLQAQPVCRK-KLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLVDYDMVHYHPSQVAAAASCLSQKVLG----------QGKWNLKQQYYTG-YMESEILEVMQHMAKNVVKVNENLTKFIVP------------VYICMLYTEEM---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30276-1", "uniprot_id": "CCNB2_MOUSE", "id": "P30276-1", "name": "G2/mitotic-specific cyclin-B2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALLRRPTVSSDLKNIDTEVIPKAK---------SHVTIR-RAVLEEIG----------------------------------NKVRNR-TTQVAKKPQ----------------------------NTKVPALPTKVTNVNK------------------------------------------------------QPKPTASVKPVQMEALAPK-----DRPPAPEDVS-------------MKEESLCQAFSDA-----------LLCKIEDIDNEDRENPQLCSDYVKDIYQYLRQLE-VLQSINPHFLDGRDINGRMRAILVDWLVQVHSKFRLLQETLYMCIAIMDRFLQAQLVCRK-KLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLVDYDMVHYHPSQVAAAASCLSQKVLG----------QGKWNLKQQYYTG-YMESEVLEVMQHMAKNVVKVNDNRTKFIAVKNKYASSRLLKISTIPQLNSKIIKDLASPLLGSP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95067-1", "uniprot_id": "CCNB2_HUMAN", "id": "O95067-1", "name": "G2/mitotic-specific cyclin-B2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALLRRPTVSSDLENIDTGVNSKVK---------SHVTIR-RTVLEEIG----------------------------------NRVTTR-AAQVAKKAQ----------------------------NTKVPVQPTKTTNVNK------------------------------------------------------QLKPTASVKPVQMEKLAPK-----GPSPTPEDVS-------------MKEENLCQAFSDA-----------LLCKIEDIDNEDWENPQLCSDYVKDIYQYLRQLE-VLQSINPHFLDGRDINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRK-KLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLIDYDMVHYHPSKVAAAASCLSQKVLG----------QGKWNLKQQYYTG-YTENEVLEVMQHMAKNVVKVNENLTKFIAIKNKYASSKLLKISMIPQLNSKAVKDLASPLIGRS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20439-1", "uniprot_id": "CCNB_DROME", "id": "P20439-1", "name": "G2/mitotic-specific cyclin-B", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVGTTLKMRGDENASENFKQVQLKKLTVPSMEATTKRAALGDLQNRGISRPIAAKDAAQKDSKDLKLTDALRNAKARVDSHWKKQPLGSTNGNGNGAVPPKVNEGGVSAFLRSNSVRNRVPTKTTVEPT----------------------------KVTVKSSSSENVNEPTLKREDSNLSKKSLTKLRAALAKPVMGVSGIRREPVAVS--------------RKEAETKKELPETKKDSLEVKKDATRMPLIRGNSAVT----------TTTSTMPTTMSLSSK-----------RLAGIEDIDANDKENLVLVSEYVNDIYDYLYQVELEQPIHKDHLAGQKEVSHKMRAVLIDWINEVHLQFHLAAETFQLAVAIIDRYLQVVKDTKRTYLQLVGVTALFIATKYEELFPPAIGDFVFITDDTYTARQIRQMELQIFKAIDCNLSRPLPIHFLRRYSKAAGAEDEHHTMSKYFIELASVDYEMATYRPSEIAAASLFLSLHLLNGNHRAGTGFNDRHWTPTLTFYSR-YSAAHLRPITRLIAK--LARDAPQAKLKAIYNKYQGSKFQKIALRTELTGALMDSIVGQSQRK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24869-1", "uniprot_id": "CG22_YEAST", "id": "P24869-1", "name": "G2/mitotic-specific cyclin-2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNPIENTENSQNTSSSRFLRNVQRLALNNVTNTTFQKSNANNPALTNFKSTLNSVKKEGSRIPQFTRESVSRSTAAQEEKRTLKEN-----------------------GIQLPKNNLLDDKENQDPSSQQ----------------------------FGALTSIKEGRAELPANISLQESSSAKEIIQHDPLKG--------------------------------VGSSTEVVHNSVENEKLHPARSQLQVRNTESETDSGKKRPISTIVEQELPKKFKVCDENGK-----------EEYEWEDLDAEDVNDPFMVSEYVNDIFEYLHQLEVITLPKKEDLYQHRNIHQ-NRDILVNWLVKIHNKFGLLPETLYLAINIMDRFLGKELVQLD-KLQLVGTSCLFIASKYEEVYSPSIKHFASETDGACTEDEIKEGEKFILKTLKFNLNYPNPMNFLRRISKADDYDIQSRTLAKFLLEISLVDFRFIGILPSLCAAAAMFMSRKMLG----------KGKWDGNLIHYSGGYTKEELAPVCHMIMDYLVSP----IVHDEFHRKYQSRRFMKASIISVQWALKVRKNGYDIMTLHE---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9I7I0-1", "uniprot_id": "CCNB3_DROME", "id": "Q9I7I0-1", "name": "G2/mitotic-specific cyclin-B3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPTKATTRAAITSGHHQLQQAVNPILGALGAATRKGLTRRAAATGNIDPNVENMQTRAKRKADHSPIKNDKIKRSALGNLTNNVKIMTLHPAQDEEQSGVGKKPTAQQLQALMDAKKQENLSVNVFGASKMTTRASSKVEDSVENCHKVLDKLEEALARPKPRPKA----------------------------VPAAKKTVLGEVQLPAMPNPMQIPVLLPPTHNLAAPQVAAVKPVRRISNDFNKT--------------EDSLYMSALEDVSSCDSMRLSGNFEAARRRSAKLQQKTEQQPQPLLLTLPETAPSQVVPIPP-----------VPEEVEDFDRKNWDDPFQVSHYAMDIFNYLKVRE-AEFPIADYMPRQIHLTTWMRTLLVDWMVEVQETFELNHETLYLAVKIVDLYLCREVINKE-KLQLLGAAAFFIACKYDERQPPLIEDFLYICDGAYNHDELVRMERETLRVIKYDLGIPLSYRFLRRYARCAKVPMPTLTLARYILELSLMDYANISFSDSQMASAALFMALRMHGGPGQ----LDKQTWTSTLIYYTG-YQLADFAEIVTALNAGLHRK--PRATIKTIRNKYSHKIFHEVAKVPLLTNQELFQGNLDLNESNLS--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8WWL7-1", "uniprot_id": "CCNB3_HUMAN", "id": "Q8WWL7-1", "name": "G2/mitotic-specific cyclin-B3", "aln": "MLLPLPPQSSKPVPKKSQSSKIVPSHHDPSEKTGENCQTKISPSSLQESPSSLQGALKKRSAFEDLTNASQCQPVQPKKEANKEFVKVVSKKINRNTHALGLAKKNKRNLKWHKLEVTPVVASTTVVPNIMEKPLILDISTTSKTPNTEEASLFRKPLVLKEEPTIEDETLINKSLSLKKCSNHEEVSLLEKLQPLQEESDSDDAFVIEPMTFKKTHKTEEAAITKKTLSLKKKMCASQRKQSCQEESLAVQDVNMEEDSFFMESMSFKKKPKTEESIPTHKLSSLKKKCTIYGKICHFRKPPVLQTTICGAMSSIKKPTTEKETLFQELSVLQEKHTTEHEMSILKKSLALQKTNFKEDSLVKESLAFKKKPSTEEAIMMPVILKEQCMTEGKRSRLKPLVLQEITSGEKSLIMKPLSIKEKPSTEKESFSQEPSALQKKHTTQEEVSILKEPSSLLKSPTEESPFDEALAFTKKCTIEEAPPTKKPLILKRKHATQGTMSHLKKPLILQTTSGEKSLIKEPLPFKEEKVSLKKKCTTQEMMSICPELLDFQDMIGEDKNSFFMEPMSFRKNPTTEETVLTKTSLSLQEKKITQGKMSHLKKPLVLQKITSEEESFYKKLLPFKMKSTTEEKFLSQEPSALKEKHTTLQEVSLSKESLAIQEKATTEEEFSQELFSLHVKHTNKSGSLFQEALVLQEKTDAEEDSLKNLLALQEKSTMEEESLINKLLALKEELSAEAATNIQTQLSLKKKSTSHGKVFFLKKQLALNETINEEEFLNKQPLALEGYPSIAEGETLFKKLLAMQEEPSIEKEAVLKEPTIDTEAHFKEPLALQEEPSTEKEAVLKEPSVDTEAHFKETLALQEKPSIEQEALFKRHSALWEKPSTEKETIFKESLDLQEKPSIKKETLLKKPLALKMSTINEAVLFEDMIALNEKPTTGKELSFKEPLALQESPTYKEDTFLKTLLVPQVGTSPNVSSTAPESITSKSSIATMTSVGKSGTINEAFLFEDMITLNEKPTTGKELSFKEPLALQESPTCKEDTFLETFLIPQIGTSPYVFSTTPESITEKSSIATMTSVGKSRTTTESSACESASDKPVSPQAKGTPKEITPREDID-EDSSDPSFNPMYAKEIFSYMKERE-EQFILTDYMNRQIEITSDMRAILVDWLVEVQVSFEMTHETLYLAVKLVDLYLMKAVCKKD-KLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQEYHYVQEKASKLAAASLLLALYMKK----------LGYWVPFLEHYSG-YSISELHPLVRQLNKLLTFS--SYDSLKAVYYKYSHPVFFEVAKIPALDMLKLEEILNCDCEAQGLVL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : .*.* .: : . *. :*: *: * .: * :*::*: ::: * : **: : : ::* :: ***:* :.:::* *::* .* : .* :. :: * :. :. :. * . .**** :: *::::: *:: :: * *:.: :: : * .* : . : : : ", "identical_positions": 34, "similar_positions": 76, "identity": "2.41%" }, { "cls_id": "homologset.agr.SGD:S000006324", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24860-1", "uniprot_id": "CCNB1_MOUSE", "id": "P24860-1", "name": "G2/mitotic-specific cyclin-B1", "aln": "------------------------------MALRVTRNTKINAENKAKVSMAGAKRVPVTVTAASKPGLRPRTALGDIG----------------------------------NKVSEELQARVPLKREAKTLGTGKGTVKALPKPVEKVPVCEPEVELA-------------------------EPEPEPELEHVREEKLSPEPILVDNPSPSPMETSGCAPAEEYLCQAFSDVILA-VSDVDADDGADPNLCSEYVKDIYAYLRQLE-EEQSVRPKYLQGRE---VTGNMRAILIDWLIQVQMKFRLLQETMYMTVSIIDRFMQNSCVPKK-MLQLVGVTAMFIASKYEEMYPPEIGDFAFVTNNTYTKHQIRQMEMKILRVLNFSLGRPLPLHFLRRASKVGEVDVEQHTLAKYLMELSMLDYDMVHFAPSQIAAGAFCLALKILD----------NGEWTPTLQHYLSYSEDSLLPVMQHLAKNVVMVNCG-LTKHMTVKNKYAASKH--AKISTLAQLNCTLVQNLSKAVTKA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30277-1", "uniprot_id": "CCNB1_RAT", "id": "P30277-1", "name": "G2/mitotic-specific cyclin-B1", "aln": "------------------------------MALRVTRNTKINTENKAKVSMAGAKRVPVAV-AASKPLLRSRTALGDIG----------------------------------NKVSE--QSRIPLKKETKKLGSGTVTVKALPKPVDKVPVCEPEVELD-------------------------EPEPEP----VMEVKHSPEPILVDTPSPSPMETSGCAPAEEYLCQAFSDVILA-VSDVDADDGGDPNLCSEYVKDIYAYLRQLE-EEQSVRPKYLLGRE---VTGNMRAILIDWLIQVQMKFRLLQETMYMTVSIIDRFMQDSCVPKK-MLQLVGVTAMFIASKYEEMYPPEIGDFAFVTNNTYTKHQIRQMEMKILRVLNFSLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELSMLDYDMVHFAPSQIAAGAFCLALKILD----------NGEWTPTLQHYLSHTEESLLPVMQHLAKNIVMVNRG-LTKHMTIKNKYATSKH--AKISTLAQLNCTLVQNLSKAVTKA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14635-1", "uniprot_id": "CCNB1_HUMAN", "id": "P14635-1", "name": "G2/mitotic-specific cyclin-B1", "aln": "------------------------------MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIG----------------------------------NKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEP----------------------VPEPEPEPEPEPVKEEKLSPEPILVDTASPSPMETSGCAPAEEDLCQAFSDVILA-VNDVDAEDGADPNLCSEYVKDIYAYLRQLE-EEQAVRPKYLLGRE---VTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKK-MLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILD----------NGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQG-LTKHMTVKNKYATSKH--AKISTLPQLNSALVQDLAKAVAKV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5M857-1", "uniprot_id": "Q5M857_RAT", "id": "Q5M857-1", "name": "", "aln": "------------------------------MALLRRPTVSSDLKNIDTGVNPKAK---------SHVTVR-RAVLEEIG----------------------------------NKVRAR-PAQVAKKPQNTKVPVQPTKAINASK----------------------------------------QPKPTASVKPVQMETLAPK-----DPLPAPEDVS---MKEESLCQAFSDALLCKIEDIDNEDGENPQLCSDYVKDIYQYLRQLEQALQSINPHFLDGRD---INGRMRAILVDWLVQVHSKFRLLQETLYMCIAIMDRFLQAQPVCRK-KLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLVDYDMVHYHPSQVAAAASCLSQKVLG----------QGKWNLKQQYYTGYMESEILEVMQHMAKNVVKVNEN-LTKFIAVKNKYASSRL--LKISTIPQLNSRTIKDLASPLMGRP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6A3R0-1", "uniprot_id": "A0A8I6A3R0_RAT", "id": "A0A8I6A3R0-1", "name": "", "aln": "------------------------------MALLRRPTVSSDLKNIDTGVNPKAK---------SHVTVR-RAVLEEIG----------------------------------NKVRAR-PAQVAKKPQNTKVPVQPTKAINASK----------------------------------------QPKPTASVKPVQMETLAPK-----DPLPAPEDVS---MKEESLCQAFSDALLCKIEDIDNEDGENPQLCSDYVKDIYQYLRQLE-ALQSINPHFLDGRD---INGRMRAILVDWLVQVHSKFRLLQETLYMCIAIMDRFLQAQPVCRK-KLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLVDYDMVHYHPSQVAAAASCLSQKVLG----------QGKWNLKQQYYTGYMESEILEVMQHMAKNVVKVNEN-LTKFIVP--------------VYICMLYTEEM-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30276-1", "uniprot_id": "CCNB2_MOUSE", "id": "P30276-1", "name": "G2/mitotic-specific cyclin-B2", "aln": "------------------------------MALLRRPTVSSDLKNIDTEVIPKAK---------SHVTIR-RAVLEEIG----------------------------------NKVRNR-TTQVAKKPQNTKVPALPTKVTNVNK----------------------------------------QPKPTASVKPVQMEALAPK-----DRPPAPEDVS---MKEESLCQAFSDALLCKIEDIDNEDRENPQLCSDYVKDIYQYLRQLE-VLQSINPHFLDGRD---INGRMRAILVDWLVQVHSKFRLLQETLYMCIAIMDRFLQAQLVCRK-KLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLVDYDMVHYHPSQVAAAASCLSQKVLG----------QGKWNLKQQYYTGYMESEVLEVMQHMAKNVVKVNDN-RTKFIAVKNKYASSRL--LKISTIPQLNSKIIKDLASPLLGSP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95067-1", "uniprot_id": "CCNB2_HUMAN", "id": "O95067-1", "name": "G2/mitotic-specific cyclin-B2", "aln": "------------------------------MALLRRPTVSSDLENIDTGVNSKVK---------SHVTIR-RTVLEEIG----------------------------------NRVTTR-AAQVAKKAQNTKVPVQPTKTTNVNK----------------------------------------QLKPTASVKPVQMEKLAPK-----GPSPTPEDVS---MKEENLCQAFSDALLCKIEDIDNEDWENPQLCSDYVKDIYQYLRQLE-VLQSINPHFLDGRD---INGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRK-KLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLIDYDMVHYHPSKVAAAASCLSQKVLG----------QGKWNLKQQYYTGYTENEVLEVMQHMAKNVVKVNEN-LTKFIAIKNKYASSKL--LKISMIPQLNSKAVKDLASPLIGRS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20439-1", "uniprot_id": "CCNB_DROME", "id": "P20439-1", "name": "G2/mitotic-specific cyclin-B", "aln": "MVGTTLKMRGDENASENFKQVQLKKLTVPSMEATTKRAALGDLQNRGISRPIAAKDAAQKDSKDLKLTDALRNAKARVDSHWKKQPLGSTNGNGNGAVPPKVNEGGVSAFLRSNSVRNRVPTKTTVEPTKVTVKSSSSENVNEPTLKREDSNLSKKSLTKLRAALAKPVMGVSGIRREPVAVSRKEAETKKELPETKKDSLEVKKDATRMPLIRGNSAVTTTTSTMPTTMSLSSKRLAGIEDIDANDKENLVLVSEYVNDIYDYLYQVELEQPIHKDHLAGQKE---VSHKMRAVLIDWINEVHLQFHLAAETFQLAVAIIDRYLQVVKDTKRTYLQLVGVTALFIATKYEELFPPAIGDFVFITDDTYTARQIRQMELQIFKAIDCNLSRPLPIHFLRRYSKAAGAEDEHHTMSKYFIELASVDYEMATYRPSEIAAASLFLSLHLLNGNHRAGTGFNDRHWTPTLTFYSRYSAAHLRPITRLIAK--LARDAP-QAKLKAIYNKYQGSKF--QKIALRTELTGALMDSIVGQSQRK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P30283-1", "uniprot_id": "CGS5_YEAST", "id": "P30283-1", "name": "S-phase entry cyclin-5", "aln": "------------------------MGENHDHEQSIKRNSMIYNENERQLCNSNLKILQNKRALSKNDSSSKQQVQDSKP----------------------------------RRALTDVPVNNNPLSQNKRIVAGSKAAKVRREEN-------------------------------------IRPIVSAVQKRQIYNDRTAAEQEEEEEEEGEDDDAASIVNKKRRIDAEGVSEIVGWQDLDYVEKDDTAMVAEYSAEIFAFLYRRELETLPSHNYLLDKTSKYYLRPSMRTILVDWLVEVHEKFQCYPETLFLSINLMDRFLAKNKVTMN-KLQLLAVTSLFIAAKFEEVNLPKLAEYAYITDGAASKNDIKNAEMFMLTSLEFNIGWPNPLNFLRRISKADDYDPVNRNIGKFILEYAYCCHQFIHLPPSTVSAMAMYIARRMTNRN-------KNELWNGTLQHYSGGIDPIHDEAFQSLCIDLVKDIASSKTHLDSLILKYKKPRYGSVYFQTFKWCTSEMHSNFQNLFNLK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* * : : . . . . . . : . : .*:* : : : ::* :*: :* : * . . : **::*:**: :*: :*: **: : : ::**:: . ***:.:*::::*:*:**: * : ::.::*:.: : :*:: * :: :. :. * *::**** ** : ::.:.*:::* : ::: ** ::* : :: :: . : *. . .* : :. : :: ", "identical_positions": 46, "similar_positions": 104, "identity": "8.53%" }, { "cls_id": "homologset.agr.SGD:S000006326", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VP94-1", "uniprot_id": "Q9VP94_DROME", "id": "Q9VP94-1", "name": "", "aln": "MCFRPRLGLRRITKQVQKWLNRQQYPMSTASVVVQYHEEPDKSDGDSKLYRALTLSNGLRAMLISDSYIDEPSIHRASRESLNSSTENFNGKLAACAVLVGVGSFSEPQQYQGLAHFVEHMIFMG-SEKFPVENEFDSFVTKSGGFSNAHTENEETCFYFELDQTH------LDRGMDLFMNLMKAPLMLPDAMSRERSAVQSEFEQTHMRDEVRRDQILASLASEGYPHGTFSWGNYKTLKEG--VDDSSLHKELHKFYRDHYGSNRMVVALQAQLSLDELEELLVRHCADIP----------------------------TSQQNSIDVSQLNYQKAFRDQFYKDVFLVQPVEDVCKLELTWVLPPMKNFYRSKPD--------------MFISQLIGYEGVGSLCAYLRHHLWCISVVAGVAESSFDSNSIYSLFNICIYLSDDGFDHIDEVLEATFAWVKLIINSDQLQDSYKESQQIENNNFRFQIEP-PPIDHVQSIV----ESFNYLPSKDVLTGPQLYFQYEESAIELLRQHMN--------KFNFNIMISSYIPYE-------------------KNEYDQREPWFGTQFKTISMPPKWQTMWEQSATIKELHYPQPNPFVT-------------------TDFKIHWVESGKPHVSRSPKALIRNDLCELWFRQDNIFKLPDG--YINLYFITPLVRESVKQYMLGVLFTYLVEFRMAEQLYPALEAGLTYGLYIGDKG---LVMRVSGYNEKLPLLVEIILNMMQTIELDIGQVNAFKDLKKRQIYNALINGKSLNLDLRLS------ILENKRFSMISKYESVDDITMDDIKSFKENFHKK-MYVKGLIQGNFTEDQAT------DLMQKVLDTYKSEKLDNLSALDNHLLQIPLGSYYLRAKTLNEDDSNTIITNYYQIGP-SDLKMECIMDLVELIVEEPFFNQLRTQEQLGYSLGIHQRIGYGVLAFLITINTQETKHRADY------------VEQRIEAFRSR------MAELVSQMSDTEFKN-------IRETLINGKKLGDTSLDEEVLRN-------------------------------------WSEIVTKEYFFNRIETQIQMLSHLTKEDVLN---------FLNDN----DKNNLRKLSVQVVGN-HNQTSNSTAQASRSGSLSDLLDDVQDNMANETDSAKPMTDKIRLEFLGESDDPSSIKDIYAFKKDLYVFPLFNTNPNLANKS--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40851-1", "uniprot_id": "AXL1_YEAST", "id": "P40851-1", "name": "A-factor-processing protease AXL1", "aln": "------MSLREVTNYEVSFYIPLSYSN--------------------RTHKVCKLPNGILALIISDP----------------------TDTSSSCSLTVCTGSHNDPKDIAGLAHLCEHMILSAGSKKYPDPGLFHTLIAKNNGSQNAFTTGEQTTFYFELPNTQNNGEFTFESILDVFASFFKEPLFNPLLISKEIYAIQSEHEGNISSTTKIFYHAARILANPDHPFSRFSTGNIHSLSSIPQLKKIKLKSSLNTYFENNFFGENITLCIRGPQSVNILTKLALSKFGDIKPKSAVKERSISIRTRSFRRSKSLKKRQDSSKNDYSDLKTFKILNTTWEKKYKNTMCFQQFPECNSIFINSNKVPIMRLLFPVSDKNTRFTKDDIKIYSHLWCELFGDESPGSLSYYLASKGWLTGCFAFTSEFAIGDIGLILELELTNSGWEN-IKRITTIVLNRLLPSFYVMNIDYLITFLKEQNLIDLVSFLYQSSEDLPMEECSKLSGILQDDLECLTPPNIFKGFKSLIEIDDPNIEKYENTKANIQWWTGQAIKFQNFLKSFMNHDNMRLLLLGNIKSGNIFDKMKNKSDICTDFFYEFEYYTANVHLASDNKFHSNSSYEFNFPTGNLFLPDCVSDPLKLQQLFLECSLKSKFATLRPQIYSEPTRTKPQLVSENQNYEMWILKEDPNFASDNKSVVSFEVLGLGIKPSPEATIHLEVLAQALFIITSSFLYPALRIGYTYEIASSSKGNVTLRFTISGFPEGVFTIVKTFVDTLKLIATDPTFLSKDTLRKARILVRNKYKNASSDNCVKLASVGLLIVLEKYIWTLEDRINALELTELESFEKFCFLFWRNPKHLVLFMQGSLEYADAINRYLNNNFTQHLKISNEGSKPTIRLYPPPSTKDLDQGTNAFISYNGHQDDPNNSIVYFIQTAQRDDIKNLTLTFLTEYLFSLTLVPDLRNKKQIGYIVLGGLRVLTDTVGIHITVMSGSSGHNLETRINEYLSYLQLQVLNRFTEFDFRRILLEPFLNLLKQNSTKQFEGSAGPVDLLNEIVANVQNGDNYTLNNKQMRQHRKVRNKIAEGRLNFQEDHEMIDISFLQKLTLKKYLAFFESKISIYSAQRSKLSIMITSPMAEKEIASRKMFLQLEAFLKINGFAIKNEDLKKIVEHSKGNPILLVKNLFTYFRRRNEVFKLGTVVLQEILKIIGMNLKQRYGSILGFSSQDGEGQEIEKFWNNDTSPIVPLQELPEPNFFRKAAF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.**.:*: .: .*. : ::. .*.**: *::***. ... ::*:: * .**..:*:: ****: ****: . *:*:* . *.::::*..* .**.* .*:* ***** :*: :: :*:* .::* **: * :*:* *:***.* . : **. .:*.. ** ** ::*.. :.. .*:..*:.::.::: .:.:.:.::. *:: * :* : : .** :*::: *:. :: :: :: **:.: .* . : .: :. *: .: . .* : .:*:* *. ***. ** : * . .* .:* ::.. .: ::: :: :.:* :: : ::* * * **.: *: .* :* . *::. ..: :.:: *.. :::.* : :: ::. ** .: ::*: ::.*:: :: **: * :* : . :* : *:::* * *:. :.* : . . .*: : .*: *:*: ::: .*. :.: .: :: * : : ::: : : :. *****. * ** : ..** * : :**: * : :*: ::: :: * * :. . * * : . :. * : ::*: :**: ::: .: :::: ::.::.* * :: :: ::**.: :* :: *:: : :..* :: *: : : . ::**.*. *. : * . .*:* : *.* :.. .:. :**.::*:** : *: ..:.: **: : .: *. : * :*: * * : :*:.* * .:*:. :.* : * :: .: :*::: :*: : * . * :* : .* : * :::::: . **: * .:::*:*: : ** ..* : * ..: .* * ::: : . * * .:..: ..*:.:: ... * .:**: .*: ", "identical_positions": 203, "similar_positions": 422, "identity": "16.15%" }, { "cls_id": "homologset.agr.SGD:S000006329", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIN6-1", "uniprot_id": "LETM1_RAT", "id": "Q5XIN6-1", "name": "Mitochondrial proton/calcium exchanger protein", "aln": "MASILLRSCRGRGPARLASP-RAASPRGSLRDRACLSCTRTVGLTSHESVLSRCCTP-ANPVYLYFKSEPLS---------------CWTQRPECQGTVAR---AAWTPASARLV--------VTGPQYLPVRGWHSSSPLGEDSMIEKSLKSLKDKNKKLEEGGPVYSPPAQVV-VKKSLGQKILDELKHYYHGFRLLWIDTKIAARMLWRILNGHTLTRRERRQFLRICADLFRLVPFLVFVVVPFMEFLLPVVVKLFPNMLPSTFETQSIKEERLKKELRVKLELAKFLQDTIEEMALKNKAAKGNATK---DFSAFFQKIRETGERPSNEEIMRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLTMRLRSIKADDKLISEEGVDSLTVKELQAACRARGMRALGVTEDRLKGQLKQWLDLHLYHEIPTSLLILSRAMYLPDTLSPADQLKSTLQTLPEIVAKEAQVKAAEVEGEQVDNKAKLEATLQEEAAIQQEHLE-ELKRAA-------ETAKDIQPEVAEATVPGRPGAELQPKMVDVIPPSEILKDTAPVLEGLKGEEITKEEIDILSDACSKLKEQKKSLTKEKEELELLKEDVQDYSEDLQEIKKELSKTGDEKYIEESTASKRLSKRVQQMIGQIDGLITQLETTQQ--NGKLDPAAASSPTGES---VISVDELISAMKQIKHIPEHKLISLT---------------------------------------------------------------------------------------SALDENKDGNINIDDLVKVIDLVNKEDVQISTTQVAEIVATLEKEEKVEEKEKAKEKAEKE-AAEVKN----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2I0-1", "uniprot_id": "LETM1_MOUSE", "id": "Q9Z2I0-1", "name": "Mitochondrial proton/calcium exchanger protein", "aln": "MASILLRSCRGRGPARLAPP-RAASPRGSLRDRACLSCTRTLGLTSRESVLSRCCTP-AHPVYLCFKGEPLS---------------CWTQRPECQGTAAR---TTWTPASARLV--------VTGPQYLPVRGWHSSSPLGEDSVIEKSLKSLKDKNKKLEEGGPVYSPPAQVV-VRKSLGQKVLDELRHYYHGFRLLWIDTKIAARMLWRILNGHTLTRRERRQFLRICADLFRLVPFLVFVVVPFMEFLLPVVVKLFPNMLPSTFETQSIKEERLKKELRVKLELAKFLQDTIEEMALKNKAAKGNATK---DFSAFFQKIRETGERPSNEEIMRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLTMRLRSIKADDKLISEEGVDSLTVKELQAACRARGMRALGVTEDRLKGQLKQWLDLHLHHEIPTSLLILSRAMYLPDTLSPADQLKSTLQTLPEIVAKEAQVKVAEVEGEKVDNKAKLEATLQEEAAIQQEHLE-ELKRAS-------EAVKDIQPEVAEATLPGRPGPEPQPPVDDVILPSEVLTDTAPVLEGLKGEEITKEEIDILSDACSKLQEQKKSLTKEKEELELLKEDVQDYSEDLQEIKKELSKTGEEKYIEESAASKRLSKRVQQMIGQIDGLITQLETTQQ--DGKLGPSQS-TPTGES---VISITELISAMKQIKHIPEHKLISLT---------------------------------------------------------------------------------------SALDDNKDGNINIDDLVKVIDLVNKEDVQISTTQVAEIVATLEKEEKIEEKEKAKEKAEKE-AAEVKN----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95202-1", "uniprot_id": "LETM1_HUMAN", "id": "O95202-1", "name": "Mitochondrial proton/calcium exchanger protein", "aln": "MASILLRSCRGRAPARLPPPPRYTVPRGSPGDPAHLSCASTLGLRNCLNVPFGCCTP-IHPVYTSSRGDHLG---------------CWALRPECLRIVSR---APWTSTSVGFV--------AVGPQCLPVRGWHSSRPVRDDSVVEKSLKSLKDKNKKLEEGGPVYSPPAEVV-VKKSLGQRVLDELKHYYHGFRLLWIDTKIAARMLWRILNGHSLTRRERRQFLRICADLFRLVPFLVFVVVPFMEFLLPVAVKLFPNMLPSTFETQSLKEERLKKELRVKLELAKFLQDTIEEMALKNKAAKGSATK---DFSVFFQKIRETGERPSNEEIMRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLTMRLRSIKADDKLIAEEGVDSLNVKELQAACRARGMRALGVTEDRLRGQLKQWLDLHLHQEIPTSLLILSRAMYLPDTLSPADQLKSTLQTLPEIVAKEAQVKVAEVEGEQVDNKAKLEATLQEEAAIQQEHREKELQKRS-------EVAKDFEPERVVA-APQRPGTEPQPEMPDTVLQSETLKDTAPVLEGLKEEEITKEEIDILSDACSKLQEQKKSLTKEKEELELLKEDVQDYSEDLQEIKKELSKTGEEKYVEESKASKRLTKRVQQMIGQIDGLISQLEMDQQ--AGKLAPANG-MPTGEN---VISVAELINAMKQVKHIPESKLTSLA---------------------------------------------------------------------------------------AALDENKDGKVNIDDLVKVIELVDKEDVHISTSQVAEIVATLEKEEKVEEKEKAKEKAEKE-VAEVKS----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LY46-1", "uniprot_id": "LETM1_DANRE", "id": "Q1LY46-1", "name": "Mitochondrial proton/calcium exchanger protein", "aln": "MASILLTRSR-TPLLKTSRSLKNEFRKGKLSEGACFNCTALRLATNSPGVLGGIVWPHASSVQYLDNSSVLQRR------------LSRSPRLYCAILVPDPALPVHSRSTYHRT--------LAWPQNAPVRWVHTTGRLLDDSKVERSLRTLKDRNKKLEEGGPVYSPTVDAEPVRRTIRQRVIDEVKHYYHGFRLLWIDTTIAVRMLWRVLNGHILSRRERRQFLRTCADVFRLLPFLVFIIVPFMEFLLPVALKLFPNMLPSTFETQSKKEERLKKELRVKLEMAKFLQDTIEEIALRNKASKGNVTE---EFSTFFQKIRDSGEIPSNEQIIRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLIMKLRAIRADDKLIAEEGVDSLTANELQAACRVRGMRALGVTEERLREQLKQWLELHLNQHIPTSLLLLSRAMFLPDTLSPADQLKTTLQNLPEIMAKEAQVKVAELDFSKVDNKTKLETTLQEEAAIRQENRERELERLADAAEKAKEQTQSQEAEVLEVEGERRVDAEHALSSVDVAIHSETLRDTAPVLEGIKGEEITKEEIDMLSDACTKLKEQKNLLTKEKEELEDLKDDVQEYSEDLEEIKRELSKTGQEKAVEESKASQRLSKRVNRMIGRMDKIITELEKDKMVLDGQMDSETT-PPIGEN---LISINELITVMKQIQNIPEHKLLSIA---------------------------------------------------------------------------------------DALDENKDGKIDIDDVIKVVELIDKEDIDISTNQVAEIMVMLQKEEKLMEKEKAKEKVEKEQAAKIQN----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7TNU7-1", "uniprot_id": "LETM2_MOUSE", "id": "Q7TNU7-1", "name": "LETM1 domain-containing protein LETM2, mitochondrial", "aln": "MAFYSYNSFLAIFWTRLPGH----------------------------SVYPSCSHF-PSLAFLHLPDSHLR-------------------TAYIKNCGSR---KYSYPSLTGNN--------KVHPLRTRLPQKLHT-TCWLQHVPGKPQLEQTGK-PKAASPQPTKEAKTETTEEKRSLRQKIVNELKYYYKGFSLLWIDTKVAARIVWRLLHGNALTRRERRRLLRTCADVFRLVPFMVFIIVPFMEFLIPVFLKLFPDMLPSTFESESKKEEKQKKTMAAKLEIAKFLQETMTEMARRNRAKLGDASS---QLSSYVKQVQ-TGHKPSTKEIVRFSKLFKDQLALEHLDRPQLVALCKLLELQTFGTNNLLRFQLLMTLKSIKADDEIIAKEGVKALSVSELQSACRARGMRSLGLTEEQLCQQLTGWLDLHLKENVPPSLLLLSRTFYLIDVKPKPIELPPNIETP--------------------------KPNLGIPTPPPPESKE-------------------------------------------------NLTDSAPQLKGTKDEEFI------------QLPPVPSSLIAPAATI---------SKEAILQAKSQETS-------QNSKADSKGA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5PQQ5-1", "uniprot_id": "LETM2_RAT", "id": "Q5PQQ5-1", "name": "LETM1 domain-containing protein LETM2, mitochondrial", "aln": "MAFYSYNSFLAIFWTRLPGH----------------------------SVHPPCSHF-PPLAFFHLPDSHLR-------------------TAYMKNCGSR---KYSYPGLTGNN--------KVHPLRTRLPQKLHT-TCWLQNHPGKPQPEQIPEEPKATDPQPTKDDQTEVAEGKWSLRQKIIDEVKYYYNGFSLLWIDTKVAARIVWRLLHGQVLTRRERRRLLRTCADVFRLVPFVVFIIVPFMEFLIPVFLKLFPDMLPSTFESESKKEEKQKKMMGAKLEIAKFLQETMTEMAKRNRAKLDDDSSDSSQLSSYVKQVQ-TGHKPSTKEIVRFSKLFEDQLALEHLRRPQLVALCKLLELQAFGTNNLLRFQLLMTLRSIKADDEVIAKEGVKALSVSELQAACRARGMRSLGLTEEQLRQQLTEWLDLHLKENVPPSLLLLSRTFYLIDVKPKPIELPPSIETP--------------------------KTNLGIPSSPPPESKE-------------------------------------------------DITDPAPQLNGTK----------------------------------------------ILQAKSQETS-------QNSKANSKGA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2VYF4-1", "uniprot_id": "LETM2_HUMAN", "id": "Q2VYF4-1", "name": "LETM1 domain-containing protein LETM2, mitochondrial", "aln": "MAFYSYNSVLAIARTRFPSH----------------------------FVHPTCSSYSPSCAFLHLPDSHLN-------------------KTCMKNYESK---KYSDPSQPGNT--------VLHPG-TRLIQKLHTSTCWLQEVPGKPQLEQATKHPQVTSPQATKETGMEIKEGKQSYRQKIMDELKYYYNGFYLLWIDAKVAARMVWRLLHGQVLTRRERRRLLRTCVDFFRLVPFMVFLIVPFMEFLLPVFLKLFPEMLPSTFESESKKEEKQKKKMAVKLELAKFLQETMTEMARRNRAKMGDAST---QLSSYVKQVQ-TGHKPSTKEIVRFSKLFEDQLALEHLDRPQLVALCKLLELQTFGTNNLLRFQLLMKLKSIKADDEIIAKEGVTALSVSELQAACRARGMRSLGLTEEQLRQQLTEWQDLHLKENVPPSLLLLSRTFYLIDVKPKPIEIPLSGEAP--------------------------KTDILVELPTFTESKE-------------------------------------------------NMVDLAPQLKGTKDEDFI------------QPPPVTSSPITPSTPISLPKGPITSSEEPTLQAKSQMTA-------QNSKASSKGA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P91927-1", "uniprot_id": "LETM1_DROME", "id": "P91927-1", "name": "Mitochondrial proton/calcium exchanger protein", "aln": "MNALLRHKGRNLRTSHLAQNVYKRFLKSNCCACSSVNVTDEPAKEDELPRRSASTSVLELSRSLGTYRRFQPHANYGYDYSGYGFRHLHTSRTLLETSSSKIDATVKKLKNQQKEKVEEIMKEVANGQAAAVRASSAATATASSEKGQNASATAGSTSATASTTSLAKTADKSVAKPKKPLRTRIWDELVHYYHGFRLLFIDVAICSKLLWRVLNGKTLTRRENKQLQRTTSDLFRLIPFSVFIIVPFMELLLPLFIKFFPGMLPSTFQTSTDRQEKLRQSLSVRLEVAKFLQQTLDQMPVQHKEHSSEEAK---QFEAFFTKIRNPTEPVSNDEIIKFAKRFDDEITLDSLSREQLAALCRVLELNTIGTTTLLRFQLRLKLRSLATDDRVIAREGVDSLDLLELQQACKARGMRAYGLTEERLRFQLKEWIDLSLNEQVPPTLLLLSRTMLISDDSITTDKLKETIRVLPDAVGAHTRHAIGESEG-KVDNKTKIEIIKEEERKIREEREE-------------------EREETIAKRSAIKEEIPAPYVFAEKLSGSQDLLDHKEQSSVSETDKGISSTDVQLLSEALKTLSSDKQLVVEKETIKELKEELADYKEDVEELREVRQVVKEP--VRESRAAKLLYNRVNKMISQLDNVLNDLEARQHQIKQAESSDYAASSPTVEPQQMVHIDELVATIRRMKEASDEERFKVVGDLLVKLDADKDGVISVNEITKAVQSIDREATNIDKKQLEEFTELLSKLASRRRHEEIVHIDDLMNNIKVLKETSDEARLKHIEAVLEKFDADKDGVVTVNDIRKVLESIGRDNIKLSDKAIEELISLLDKEQVLQAEQKIEKAIAKSMKEAEKLKSEVDKADKDLSKLVNDIHDSAKEIQDIANEMRDKEETVPDKAKELKAEPAFKDTAKTLKDNAKDLDDLAKDPKSDPKSPTKASTGSGPAGLSGGGPSSGSSGIATGSTTESALREAAERQMEKILPSTDIGLPPTIQTPSQPPTSKKATATASTLSTTITAKKLL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06493-1", "uniprot_id": "YLH47_YEAST", "id": "Q06493-1", "name": "LETM1 domain-containing protein YLH47, mitochondrial", "aln": "--MLKYRSLPIKRAIHHPAP-------------------------------------------------------------------------GITPISPR----------------------IMVSRLRVIPSFNLKFNRWNSSVPESSKKELKTTDGNQESASKVSP---VKEKEKVPFKVKMQKALRHYWDGSKLLGLEIKISSKLLMKSAAGYPLTRRENLQLKRTTQDIVRLVPFAAFLIIPFAELLLPFALKLFPNLLPSTYESSKKRENKLENLRNTRKLMSEIIKNNKSHFKPNNISEEQKALFN-----RFYTHVRATGVPESRQQLIEVARLFTDDTVLDNVTRPYLIALAKYMNLQPFGTDVMLRYRIRYKMLELKKDDLSIYYEDAEQLSLSELKTACASRGIRSVDVEPSVLYSNLRLWLNMRLKDKIPSTLLIMATAYNYGNVQSKESLYDALCDVLIG-----------------------IPDELYHEVKVNVVKED--------------------------------------------------------------------------------EASAKQKLKQLREQEEIMKEEEQQEENAIVSVKDELSLDDQDKNIDAAAPDVKPHD--TKPIGEAAAIKEK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : . . . : . :: . : :*:.* ** :: :. ::: : * *:***. :: * *..**:** .*:::** *:*:*. :*:** :****:::.. :::: .: .: :::::::. .: .: . : ::: . * .:::..:: * *: .*: : * * **.: ::*:.:** :**::: : : ** * *.. * **: ** **:*: .: . * :* * :: * ..:*.:**::: : : : . : : . ", "identical_positions": 60, "similar_positions": 123, "identity": "5.78%" }, { "cls_id": "homologset.agr.SGD:S000006333", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JUK2-1", "uniprot_id": "A0A0G2JUK2_RAT", "id": "A0A0G2JUK2-1", "name": "", "aln": "---------------------------------------------------------------------------------------------MSG--GTPYIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRP--IPPRDEVFEYIIFRGSDIKDLTVCE------------------------------------PPKPQCSLPQDPAIVQSSLGSSSS-----------SFQSVGSYGPFGR--MPAYSQFSPSTLVG----QQFGA-VGVAGSSLTSFGTEASNSGTLSQSNAVGSAFTQDTRSVKPQLAQGRSSPQLDPLRKSPTMEQAVQTA---SAHLPAPAPVGRRSPVPARPLPPTSQKAID-------NQEHRR-AEVHKVPRPENEQLR---NDSKRQVVPGVPSAPRRGRGGHRGGRGRFG-----------------------------------------------IRRDGPMKFEKDFDFESANAQFNKE-----------------EIDREFHNKLKLKEDKLEKQEKPVNGEDKGDSGVDTQNSEGNADEE-DPLGPNCYYDKTKSFFDNISCDDN-------------RERRPTWAEERRLNAETFGIPLRPNRGRGGYRGRGGLGFRGGRGRGSGRGGTFTAPRGFRAGFRGARGGREFADFEYRVSPGFGPQLRGGKKKKKKKKN-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K2F8-1", "uniprot_id": "LS14A_MOUSE", "id": "Q8K2F8-1", "name": "Protein LSM14 homolog A", "aln": "---------------------------------------------------------------------------------------------MSG--GTPYIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRP--IPPRDEVFEYIIFRGSDIKDLTVCE------------------------------------PPKPQCSLPQDPAIVQSSLGSSSS-----------SFQSVGSYGPFGR--MPAYSQFSPSTLVG----QQFGA-VGVAGNSLTSFGTEASNSGTLSQSNAVGSAFTQDTRSVKPQLAQGRSSPQLDPLRKSPTMEQAVQTA---SAHLPAPAPVGRRSPVPARPLPPTSQKAID-------NQEHRR-AEVHKVPRPENEQLR---ND-KRQVVPGVPSAPRRGRGGHRGGRGRFG-----------------------------------------------IRRDGPMKFEKDFDFESANAQFNKE-----------------EIDREFHNKLKLKEDKLEKQEKPVNGEDKGDSGVDTQNSEGNADEE-DPLGPNCYYDKTKSFFDNISCDDN-------------RERRPTWAEERRLNAETFGIPLRPNRGRGGYRGRGGLGFRGGRGRGSGRGGTFTAPRGFRAGFRGARGGREFADFEYRKTTAFGP-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8ND56-1", "uniprot_id": "LS14A_HUMAN", "id": "Q8ND56-1", "name": "Protein LSM14 homolog A", "aln": "---------------------------------------------------------------------------------------------MSG--GTPYIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRP--IPPRDEVFEYIIFRGSDIKDLTVCE------------------------------------PPKPQCSLPQDPAIVQSSLGSSTS-----------SFQSMGSYGPFGR--MPTYSQFSPSSLVG----QQFGA-VGVAGSSLTSFGTETSNSGTLPQSSAVGSAFTQDTRSLKTQLSQGRSSPQLDPLRKSPTMEQAVQTA---SAHLPAPAAVGRRSPVSTRPLPSASQKAGE-------NQEHRR-AEVHKVSRPENEQLR---NDNKRQVAPGAPSAPRRGRGGHRGGRGRFG-----------------------------------------------IRRDGPMKFEKDFDFESANAQFNKE-----------------EIDREFHNKLKLKEDKLEKQEKPVNGEDKGDSGVDTQNSEGNADEE-DPLGPNCYYDKTKSFFDNISCDDN-------------RERRPTWAEERRLNAETFGIPLRPNRGRGGYRGRGGLGFRGGRGRGGGRGGTFTAPRGFRGGFRGGRGGREFADFEYRKTTAFGP-------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PUV2-1", "uniprot_id": "A0A8M9PUV2_DANRE", "id": "A0A8M9PUV2-1", "name": "", "aln": "---------------------------------------------------------------------------------------------MSG--GTPYIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRP--IAPRDETFEYIIFRGSDIKDLTVCE------------------------------------PPKPTCSLPQDPAIVQSSLGSSTAPPS--------SFQSGNSYGLFNRPPVAPYTQFNPSPLVS----PQFGT-VGVG-SALGLFGSETG--------SAISSAFISDN--LCGFIAEGSTSPALDSLRKSPPVESAVPSAPVVSSTLAAPG-LGRKSPVSTRVASTNTQKHVD-------LTEQTRGTDVPTVSAPESSQSRGGSKDASKRLAAGGPPAARRGRAGAHRGRGRFP-----------------------------------------------VRREGPMKFEKDFDFESANAQFNKE-----------------EIDKEFQSKLKLKD---EKPEKALNGEDKADSGVDTQNSEGNADEE-DPLGPNCYYDKTKSFFDNISCDDTRKAAERSGGSFFPRQHRQTWAEERRMNAETFGLPLR--RGRGGYRGRGGMGFRGGRGRGAGRG-SFGPHPGFRGGYRGSQGGREFADFEYRKENKIAV-------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8CGC4-1", "uniprot_id": "LS14B_MOUSE", "id": "Q8CGC4-1", "name": "Protein LSM14 homolog B", "aln": "---------------------------------------------------------------------------------------------MSGSSGTPYLGSKISLISKAQIRYEGILYTIDTDNSTVALAKVRSFGTEDRPTDRP--APPREEIYEYIIFRGSDIKDITVCE------------------------------------PPKAQHTLPQDPAIVQSSLGSASAS----------PFQPHVPYSPFRG--MPPYGQLAASSLLS----QQYAASLGLG---------------------------------------AGFPS---TPVGKSPMVEQAVQTS--------SVDNLNAKKLLPSKVTSATQLNGRQ-------AQPSSK--PASDVVQPAPVHTQGQVNDENRRPPRR-RSGNRRTRNRSR-GQNRPT-----------------------------------------------NVKENTIKFEGDFDFESANAQFNRE-----------------ELDKEFKKKLNFKD---DKADK---GEEK-DPAVMAQSEE-TAAEE-DLLGPNCYYDKSKSFFDNISSELKT------------SSRRTTWAEERKLNTETFGVSGRFLRGRS---SRG--GFRGGRGNGTTRR----NPTSHRAGT-----GRV---------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JZY0-1", "uniprot_id": "A0A0G2JZY0_RAT", "id": "A0A0G2JZY0-1", "name": "", "aln": "MGYERTGAARGGGRPRMWLRRRSSPAPLRLRLSASFRSLSRSLVARRPLGAAEGASAAAARSCAGVGGQATARRRSGRGPALVPRALRAPAAAMSGSSGTPYLGSKISLISKAQIRYEGILYTIDTDNSTVALAKVRSFGTEDRPTDRP--APPREEIYEYIIFRGSDIKDITVCE------------------------------------PPKAQHALPQDPAIVQSSLGSASAS----------PFQPHVPYSPFRG--MPPYGQLAASSLLS----QQYAASLGLEKLVSPPASAAASSPSSSPSPQPVSELDMSSEPPQLTCKGAGFPS---TPVGKSPMVEQAVQTS--------SVDNLNAKKLLPSKVTSATQLNGRQ-------AQPSSK--PASDVVQPAPVHAQGQVNDENRRPPRR-RSGNRRTRNRSR-GQNRPT-----------------------------------------------NVKENTIKFEGDFDFESANAQFNRE-----------------ELDKEFKKKLNFKD---DKAEK---GDEK-DPAVMAQSEE-TPPEE-DLLGPNCYYDKSKSFFDNISSELKT------------SSRRTTWAEERKLNTETFGVSGRFLRGRS---SRG--GFRGGRGNGTTRR----NPTSHRAGT-----GRV---------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BX40-1", "uniprot_id": "LS14B_HUMAN", "id": "Q9BX40-1", "name": "Protein LSM14 homolog B", "aln": "---------------------------------------------------------------------------------------------MSGSSGTPYLGSKISLISKAQIRYEGILYTIDTDNSTVALAKVRSFGTEDRPTDRP--APPREEIYEYIIFRGSDIKDITVCE------------------------------------PPKAQHTLPQDPAIVQSSLGSASAS----------PFQPHVPYSPFRG--MAPYGPLAASSLLS----QQYAASLGLG---------------------------------------AGFPS---IPVGKSPMVEQAVQTG--------SADNLNAKKLLPGKGTTGTQLNGRQ-------AQPSSK--TASDVVQPAAVQAQGQVNDENRRPQRR-RSGNRRTRNRSR-GQNRPT-----------------------------------------------NVKENTIKFEGDFDFESANAQFNRE-----------------ELDKEFKKKLNFKD---DKAEK---GEEK-DLAVVTQSAE-APAEE-DLLGPNCYYDKSKSFFDNISSELKT------------SSRRTTWAEERKLNTETFGVSGRFLRGRS---SRG--GFRGGRGNGTTRR----NPTSHRAGT-----GRV---------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PF20-1", "uniprot_id": "M9PF20_DROME", "id": "M9PF20-1", "name": "", "aln": "---------------------------------------------------------------------------------------------MSG--GLPELGSKISLISKADIRYEGRLYTVDPQECTIALSSVRSFGTEDRDTQFQ--IAPQSQIYDYILFRGSDIKDIRVVNNHTLPHHNDPAIMQAQLQNGPPQMPQHFPMPSGMSGPPQQQQVPSQQPPQMPSGGGSGGAGGAGAPGGGGPGYGNGNPFGNLGGPNLANMVGNAGGSLAPGSGAPGSGPFMHIGGNQQQPKPQQQKQPISVLDMLAGASRSTTPISLIVSPTAELTQQQQLHQQQNAGQGGNGRDAGHKRQNHQQQQNQQHQQRGGPSHNNMQQQQQRGGGSGTDFYNQQRDRRDSGRQMDNNYSNNYNNNNNNQRNRGGGNGMQQQQRGGNGGSGGGGGNGGGNNPAWNMHRGNQNSNNMMNMRNRGMGSRGPMRPNQGYRPQSANNQNKPRNKIKFEGDFDFEQANNKFEELRSQLAKLKVAEDGAPKPATNATAATATATNEQVGEKVEGVHTLNGETDKKDDSGNETGAGEHEPEEDDVAVCYDKTKSFFDNISCEAAQDRS---------KNKKNDWRQERKLNTETFGVSSTR-RGSS---YRGRNQYYNNNGNGGINSGYGGAPGYNRNNYRMGGGGGNFRNRSNNRNNGGGRGGNGMPNITNGNTAAALKAANNAAGHGSNATDSSAPNATTATTKSTSLLPEQTQQVAAVSQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P45978-1", "uniprot_id": "SCD6_YEAST", "id": "P45978-1", "name": "Protein SCD6", "aln": "--------------------------------------------------------------------------------------------------MSQYIGKTISLISVTDNRYVGLLEDIDSEKGTVTLKEVRCFGTEGRKNWGPEEIYPNPTVYNSVKFNGSEVKDLSILD-------------------------------------------------------------------------ANINDIQPVVPQMMPPASQFPPQQAQS----------------------------------------------------------------PPQAQAQAHVQTN---------PQVPKPESNVPAAVAGYGVYTPTS---------TETATASMNDKSTPQDTNVNSQSRERGKNGENEPKYQRNKNRSSNRPPQS--------------------------------------------------NRNFKVDIPNEDFDFQSNNAKFTKG-----------------------------------------------DSTDVEKEKELESAVHKQDESDEQFYNKKSSFFDTISTSTET-------------NTNMRWQEEKMLNVDTFGQASARPRFHSRGLGRGRGNYRGNRGNRGRGG--QRGNYQNRNNYQNDSGAYQNQNDSYSRPANQFSQPPSNVEF-----------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*..***** :: ** * * :*.:: *::* .**.****.* . *. :: : *.**::**: : : . :. : . . : . .: .. .: . : ****:. * :* . * . . : . *:*..****.** . . . * :*: :*.:*** . * . ** : ...*. * . . ", "identical_positions": 52, "similar_positions": 70, "identity": "6.78%" }, { "cls_id": "homologset.agr.SGD:S000006335", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61599-1", "uniprot_id": "NAA20_HUMAN", "id": "P61599-1", "name": "N-alpha-acetyltransferase 20", "aln": "MTTLRAFTCDDLFRFNNINLDPLTETYGIPFYLQYLAHWPEYFIVAE----AP--GGELMGYIMGKAEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELLEEISERK--GGFFVDLFVRVSNQVAVNMYKQLGYSVYRTVIEYYSASN---------GEPDEDAYDMRKALSRDTEKKSIIP--LPHPVRPEDIE-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61600-1", "uniprot_id": "NAA20_MOUSE", "id": "P61600-1", "name": "N-alpha-acetyltransferase 20", "aln": "MTTLRAFTCDDLFRFNNINLDPLTETYGIPFYLQYLAHWPEYFIVAE----AP--GGELMGYIMGKAEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELLEEISERK--GGFFVDLFVRVSNQVAVNMYKQLGYSVYRTVIEYYSASN---------GEPDEDAYDMRKALSRDTEKKSIIP--LPHPVRPEDIE-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2RZ44-1", "uniprot_id": "B2RZ44_RAT", "id": "B2RZ44-1", "name": "N-alpha-acetyltransferase 20", "aln": "MTTLRAFTCDDLFRFNNINLDPLTETYGIPFYLQYLAHWPEYFIVAE----AP--GGELMGYIMGKAEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELLEEISERK--GGFFVDLFVRVSNQVAVNMYKQLGYSVYRTVIEYYSASN---------GEPDEDAYDMRKALSRDTEKKSIIP--LPHPVRPEDIE-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q58ED9-1", "uniprot_id": "NAA20_DANRE", "id": "Q58ED9-1", "name": "N-alpha-acetyltransferase 20", "aln": "MTTLRAFTCDDLFKFNNINLDPLTETYGIPFYLQYLAHWPEYFIVAE----AP--GGELMGYIMGKAEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMEMLEEISERK--GGFFVDLFVRVSNQVAVNMYKQLGYSVYRTVIEYYSASN---------GEPDEDAYDMRKALSRDTEKKSIIP--LPHPVRPEDIE-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PI14-1", "uniprot_id": "M9PI14_DROME", "id": "M9PI14-1", "name": "N-alpha-acetyltransferase 20", "aln": "MTTLRPFTCDDLFKFNNVNFDPLTETYGLSFYTQYLAKWPEYFQLAE----SP--SGQIMGYIMGKVEG--HLDNWHGHVTALTVSPDYRRLGLAALLMSFLEDISEKK--RAYFVDLFVRKSNQVAINMYTNLGYIIYRTILEYYS------------GDQDEDAYDMRKALSRDVNKKSVIP--YTQPITMRELRRQMRHDH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06504-1", "uniprot_id": "NAT3_YEAST", "id": "Q06504-1", "name": "N-terminal acetyltransferase B complex catalytic subunit NAT3", "aln": "MTTIQPFEPVDLFKTNNVNLDILTENFPLEFYFEYMIIWPDLFFKSSEMTVDPTFKHNISGYMMAKTEG--KTTEWHTHITAVTVAPRFRRISLASKLCNTLETMTDVMPHEVNFIDLFVKCNNQLAIKLYEKLGYSVYRRVVGYYNSAEDGYPDTLKKVDDNKDAFDMRKAMARDRNR-SVRPDGRSHKCYPHDVRF------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***::.* ***: **:*:* ***.: : ** :*: **: * :. * :: **:*.*.** :** *:**::*:* :**:.**: * . ** ::: *:****: .**:*:::* :*** :** :: **. : ::**:*****::** :: *: * .: .::. ", "identical_positions": 68, "similar_positions": 59, "identity": "33.33%" }, { "cls_id": "homologset.agr.SGD:S000006336", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9Q3-1", "uniprot_id": "D4A9Q3_RAT", "id": "D4A9Q3-1", "name": "Small ribosomal subunit protein uS12", "aln": "MGK--CCGLCTARKLRSHRQDQKWQDKQYKKAHLGTALKANPFGGAFHAKGIVLEKVGVEAKQPNSAIRKCVRVHLIKNGKKITAFVPNDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1LTW8-1", "uniprot_id": "F1LTW8_RAT", "id": "F1LTW8-1", "name": "Small ribosomal subunit protein uS12", "aln": "MGK--CRGLCTARKLRSHRRDQKWHDKQYKKAHLGTALKANLFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLSKYGKKITAFVPNDGCLNFIEENDKVLVVGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62267-1", "uniprot_id": "RS23_MOUSE", "id": "P62267-1", "name": "Small ribosomal subunit protein uS12", "aln": "MGK--CRGLRTARKLRSHRRDQKWHDKQYKKAHLGTALKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62268-1", "uniprot_id": "RS23_RAT", "id": "P62268-1", "name": "Small ribosomal subunit protein uS12", "aln": "MGK--CRGLRTARKLRSHRRDQKWHDKQYKKAHLGTALKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62266-1", "uniprot_id": "RS23_HUMAN", "id": "P62266-1", "name": "Small ribosomal subunit protein uS12", "aln": "MGK--CRGLRTARKLRSHRRDQKWHDKQYKKAHLGTALKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPRS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8T3U2-1", "uniprot_id": "RS23_DROME", "id": "Q8T3U2-1", "name": "Small ribosomal subunit protein uS12", "aln": "MGK--PRGLRTARKHVNHRRDQRWADKDYKKAHLGTRWKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPRDGSLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKEKKERPRS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX30-1", "uniprot_id": "RS23B_YEAST", "id": "P0CX30-1", "name": "Small ribosomal subunit protein uS12B", "aln": "MGKGKPRGLNSARKLRVHRRNNRWAENNYKKRLLGTAFKSSPFGGSSHAKGIVLEKLGIESKQPNSAIRKCVRVQLIKNGKKVTAFVPNDGCLNFVDENDEVLLAGFGRKGKAKGDIPGVRFKVVKVSGVSLLALWKEKKEKPRS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ** :*** **::::* :::*** *** *:. ***: *********:*:*:*************:* * ***:*****.**.**:::***:**:.******:* *************:.******:* ***:***", "identical_positions": 97, "similar_positions": 29, "identity": "66.9%" }, { "cls_id": "homologset.agr.SGD:S000006337", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C1D8-1", "uniprot_id": "IWS1_MOUSE", "id": "Q8C1D8-1", "name": "Protein IWS1 homolog", "aln": "MDSEYYSGDQSDDGGATPVQDERDSGSDGEDGVTEQHSGSDTGSVDHHSENETSDREDGLAKIHNGTDSENDEPSNANASDSESEELHRPKDSDSDSEEHAESPASDSENEPVNQHGSDSE-------------NEELLNGHASDSEKEEVSKHAASDS-------------EAEDTLQPQVSESDSEDPPRPQASDSENEEPPKPRISDSESEELPKP--------------------------RVSDSESEDPPRPQASDSESEELPKPRVSDSESEDPPRPQASDSESEELPKPR--VSDSESEDPQKGPASDSEAEDASRHKEKPDSDD-SDGENKREDSEVQNE---SDGHTDRKGLHSSDSEEEEPK-RQKIDSDDDEEKEGDEEKVAKRKAAVLSDSEDDAGNASAKKSRVVCDADDSDSDVVSDKSGKRETTVASDSEE-EAGKEESSVKKKEDKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKNETQLKEAEDSDSDDNIKRGKHMDFLSDFEMMLQRKKSMCGKRRRNRDGGTFISDADDVVSAMIVKMNEAAEEDRQLNNQKKPALKKLTLLPTVVMHLKKQDLKETFIDSGVMSAIKEWLSPLPDRSLPALKIREELLKILQELPSVSQETLKHSGIGRAVMYLYKHPKESRSNKDMAGKLINEWSRPIFGLTSNYKGMTREEREQRDLEQMPQRRRLS---STGGQTPRRDLEKVLTGEEKALRPGDPGFCARARVPMPSNKDYVVRPKWNVEMESSRFQASSKKGISRLDKQMRKFTDIRKKSRSAHAVKISIEGNKMPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3SWT4-1", "uniprot_id": "IWS1_RAT", "id": "Q3SWT4-1", "name": "Protein IWS1 homolog", "aln": "MDSEYYSGDQSDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVDRHSENETSDREDGLTKIHNGTDSENDEPSNVHASDSESEELHRPKDSDSESEEHAESPASDSENEAVHQQGSDSE-------------KEELLNGHASDSEKEEGRKHAASDS-------------ETEDTLQPQGSESDSEDPPRPQASDSESEEPPKPRISDSESEELPKP--------------------------RISDSESEDPPRPQVSDSESEELPKPRVSDSESEDPPRPQASDSESEELPKPR--VSDSESEDPQKGPASDSEAEDASRHKEKPESED-SDGENKREDSEVQNE---SDGHADRKGLHSSDSEEEEPK-RQKIDSDDDGEKEGDE-KVAKRKAAVLSDSEDEDKASAAKKSRVISDADDSDSDVVSDKSGKREKTVASDSEE-EVGKEESSVKKSEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKNETQLKEAEDSDSDDNIKRGKHMDFLSDFEMMLQRKKSMCGKRRRNRDGGTFISDADDVVSAMIVKMNEAAEEDRQLNNQKKPALKKLTLLPTVVMHLKKQDLKETFIDSGVMSAIKEWLSPLPDRSLPALKIREELLKILQELPSVSQETLKHSGIGRAVMYLYKHPKESRSNKDMAGKLINEWSRPIFGLTSNYKGMTREEREQRDLEQMPQRRRMS---STGGQTPRRDLEKVLTGEEKALRPGDPGFCARARVPMPSNKDYVVRPKWNVEMESSR-PGILKKGLSRLEKHKRRFAEQKRLSQMHRAVKFSIEGNRMPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96ST2-1", "uniprot_id": "IWS1_HUMAN", "id": "Q96ST2-1", "name": "Protein IWS1 homolog", "aln": "MDSEYYSGDQSDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDREDGLPKGHHVTDSENDEPLNLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPR--VSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHK-KQKMDSDED-EKEGEEEKVAKRKAAVLSDSEDEEK-ASAKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEE-EAGKELS-DKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKGETQVKEAEDSDSDDNIKRGKHMDFLSDFEMMLQRKKSMSGKRRRNRDGGTFISDADDVVSAMIVKMNEAAEEDRQLNNQKKPALKKLTLLPAVVMHLKKQDLKETFIDSGVMSAIKEWLSPLPDRSLPALKIREELLKILQELPSVSQETLKHSGIGRAVMYLYKHPKESRSNKDMAGKLINEWSRPIFGLTSNYKGMTREEREQRDLEQMPQRRRMN---STGGQTPRRDLEKVLTGEEKALRPGDPGFCARARVPMPSNKDYVVRPKWNVEMESSRFQATSKKGISRLDKQMRKFTDIRKKSRSAHAVKISIEGNKMPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8JV07-1", "uniprot_id": "A8JV07_DROME", "id": "A8JV07-1", "name": "TFIIS N-terminal domain-containing protein", "aln": "--METSEIEKAGGDEAETLSEPLEKTTTDTAAKAELKEIQDTNPDATNFEPVLPEKSKSKSPSPAPKNGDDNAEAIADRSRSRSRSATRKSASRSRSGSHKSRSGSVHSAASGRRSRSGSKQSLNGSRRSRSGSAPSRSGSRHSGAAPGSPAGSRRSRSGSRRSRSGSRQSRSGSRRSRSGSKQSHRSRSGSKRSRSGSRRSRSGSRRSRSGSKQSRGGSRRSRSGSKQSRSGSRRSRSGSKRSRSRSGSRRSNASRSGSRRSRSGSVSRRSRSGSGSRRSRSGSRRSRSGSKRSRSGSICSRSGSRRSRSGSARSRSGSRRSRSGSRRSRSGSRRSRSGSSRSRSGSGSRRSRSGSRRSRSGSSRSRSGSSRSRSGSRRSRSGSRRSRSGSRRSRSGSKRSRSGSRRSRSGSRRSRSGSRRSRSGSRRSRSGSRSRSRSISGGSRKGSRSRSGSAASQTASRRKRRAISESDDDGPKVTKKRVKITDTDNEEDEQ---DKGIGKEKSQDKITESSDDENTPISNEPENSNFISDFDAMLMRKKEEKRVRRRKRD-IDLINDNDDLIDQLIVSMKNASDDDRQLNMIGQPATKKISMLKQVMSQLIKKHLQLAFLEHNILNVLTDWLAPLPNKSLPCLQIRESILKLLSDFPTIEKGLLKQSGIGKAVMYLYKHPQETKSNRDRAGRLISEWARPIFNVSCNFSAMSKEERQERDLAQMSRHRHKSPDTEPSSSSKAPTLNQTLSNEDKMLRPGDPGWVARARVPMPSNKDYVIRPKSTVEG---EVSASTKRKPNRYEKHMKRFLDSKRLKESRRAVEISIEGRKMAL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06505-1", "uniprot_id": "IWS1_YEAST", "id": "Q06505-1", "name": "Transcription factor SPN1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTADQEQPKVVEATPEDGTASSQKSTINAENENTKQNQSMEPQETSKGTSN------DTKDPDNGEKNEEAAIDEN----------------------------------------------------------------------------------SNVEAAERKRKHISTDFSDDDLEKEEHNDQSLQPTVENRASK-----------DRDSSATPSSRQELEEKLDRILKKPKVRRTRRDEDDLEQYLDEKILRLKDEMNIAAQLDIDTLN---------------------------------------------------------KRIETGDTSLIAMQKVKLLPKVVSVLSKANLADTILDNNLLQSVRIWLEPLPDGSLPSFEIQKSLFAALNDLP-VKTEHLKESGLGRVVIFYTKSKRVEAQLARLAEKLIAEWTRPIIGASDNYRDK-RIMQLEFDSEKLRKKSVMDSAKNRKKKSKSGEDPTSRGSSVQTLYEQAAARRNRAAAPAQTTTDYKYAPVSNLSAVPTNARAVGVGSTLNNSEMYKRLTSRLNKKHK---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .:. . . .: .: .. . . . . . . :. . .* . . . : ::.: . .. . . . :: . : : . . : .* :. .: . :*:: :: : . *.: :: * :. . : . * :*:.:* *: * * .* :::: .::. : ** ***: ***.::*::.:: *.::* :. **.**:*:.*:: * : . * :** **:***:. : *: : : : * :: :: . . .: .. : * .. ** .* :..** * .:. . . . .: ::: . . .. ", "identical_positions": 48, "similar_positions": 144, "identity": "5.79%" }, { "cls_id": "homologset.agr.SGD:S000006339", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZN63-1", "uniprot_id": "D3ZN63_RAT", "id": "D3ZN63-1", "name": "WD repeat and HMG-box DNA-binding protein 1", "aln": "MPAIQKPMRYGHTEGHTEVCFDDSGSFIVTCGSDGDVRMWEDLD-DDDPKSVNVGEKAFSCALKNGKLVTAVSNNTVQVYTFPEGAPDGILTRFTTNANHVVFNGDGTKIAAGSSDFLVKVVDVMDNSQQQTFRGHDAPVLSLSFDPKDVFLASASCDGTVRVWNIS------------------------DQTCAASWPVLRKSND-------------------VVNSESICRLAWQPKTGKFLAVPVEKSVKLYRRETWSNPFDLSDSS---VTQTLNIVTWSPCGQYLAAGAINGLIVVWNVETKECMERVKHEKGYAICGLAWHPTYSRICYTDVEGNLG-ILENVCDLSGKLSSNKVPSGVEK-DYSDLFDGDDTSSAGDFLNDN--AVEIPSFSKGIRNEEDDNDDLMLAAD------HVLGDDENSVDVTMLR-NDL-HREEGEDRQASSLHSLPLVKSQRPLYDGPMPTPRQKPFQPSSTPLHLTHR-FMAWNSVGIIRCYNDDQDSAIDVEFHDTSIHHATHLSNAFNYTMGSLSHEAVLLACESADELASKLHCLHFSSWDSSKEWIVDMPENEDIEAICLGLGWAAAATSALLLRLFTIGGVQKEVFCLPGPVVSMAGHGEQLCIVYHRGTGFDGDQCLGVQLLELGRK-KKQVLHGDPLPLTRKSYLTWLGFSAEGTPCYVDSEGCVRMLNRGLGNTWTPVCNIREHCKGKSDHYWVVGIHENPQQLRCIPCKGSRFPPTLPRPAVAILPFKLPYCQTSTEKGQMEEQFWHSVLFHNYLDYLAENGYDYEESIKKQAVKEQQELLMKMLALSCKLEREFRCVELADLMTQNAVHLAIKYASRSRKLILAQKLSELAAEKAAELAEIQTEE--REEDFRERLNAGYSHTTTEWSQPRVRSQVEEDAEDREDTVSEGNPEPQNHVIGQNLIQSANSSDTPAMKSGAVFSSSQGRVNPFKVLVSSKEPAVSVNATRSANILDNMNKLSRKSTSFNRVANNEKSPVIKPLIPKPRCKQASAASYFQKRTSQAEKTEEVKE---NPKSSSSEAPAVC-LQNSEVQRPKTGFQMWLEENRSHIMSDNPDISDEADIIKEGMIRFRVLSAEERKEWTNKAKGGTASDGAEAKKRKRGVSEICETEKQEEAVKENLELSKKQKALDLSTNQKLSAFAFKQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59328-1", "uniprot_id": "WDHD1_MOUSE", "id": "P59328-1", "name": "WD repeat and HMG-box DNA-binding protein 1", "aln": "MPATQKPMRYGHTEGHTEVCFDDSGSYIVTCGSDGDVRMWEDLD-DDDPKSVNVGEKAFSCALKNGKLVTAVSNNTVQVYTFPEGVPDGILTRFTTNANHVVFNGAGNKIAAGSSDFLVKVVDVMDNSQQQTFRGHDAPVLSLSFDPKDIFLASASCDGTVRVWNIS------------------------DQTCAVSWPVLQKSND-------------------VVNAKSICRLAWQPKAGKLLAVPVEKSVKLYRRETWSNPFDLSDSS---ISQTLNIVTWSPCGQYLAAGAINGLIVVWNVETKDCMERVKHEKGYAICGLAWHPTCSRICYTDVEGNLG-VLENVCDLSGKVSSNKVSSRVEK-DYNDLFDGDDTSSAGDFLNDN--AVEIPSFSKGIINEDDDNDDIMLAAD------HDLGDDENSVDVTMLK-ADLSHKEEGDDDQARSIHNLPLIRPQRPFYDGPMPTPRQKPFQSSSTPLHLSHR-FMVWNSVGIIRCYNDDQDSAIDVEFHDTSIHHATHLLNAFNYTMGTLSHEAILLACESADELASKLHCLHFSSWDSSKEWMVDMPQNEDIEAICLGLGWAAAATTALLLRLFTIGGVQKEVFCLPGPVVSMAGHGEQLCIVYHRGTGFDGDQCLGVQLLELGRK-KNQVLHGDPLPLTRKSYLTWLGFSAEGTPCYVDSEGCVRMLNRGLGNTWTPVCNIREHCKGKSDHYWVVGIHENPQQLRCIPCKGSRFPPTLPRPAVAILSFKLPYCQTSTEKGQMEEQFWHSVLFHNYLDYLAKNGYDYEESIKNQAVKEQQELLMKMLALSCKLEREFRCVELADLMTQNAVHLAIKYASRSRKLILAQKLSELAAEKAAELAETQSEEE-KEEDFREKLNAGYSHTTTEWSRPRVRSQVED-AEDREDTVSEEKPESHNH--GQNLFQSANSSDTPALKSGAVFSSSQGWVNPFKVVVSSKEPAVSANSTRSANILDSMNKSSRKSTSLNRMENNEKSPVIKPLTPKPRSKQASAASYFQKRTPQADKTEEVKE---NPKSSSSDAPAVC-LQNSENQRPKTGFQMWLEENRSQILSDNPDISDETDIIKEGMIRFRVLSAEERKAWTNKAKGETASDGAEAKKRKRVVSEICETENQEETVKENLDLSKKQKALNLPANQKLSAFAFKQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75717-1", "uniprot_id": "WDHD1_HUMAN", "id": "O75717-1", "name": "WD repeat and HMG-box DNA-binding protein 1", "aln": "MPATRKPMRYGHTEGHTEVCFDDSGSFIVTCGSDGDVRIWEDLD-DDDPKFINVGEKAYSCALKSGKLVTAVSNNTIQVHTFPEGVPDGILTRFTTNANHVVFNGDGTKIAAGSSDFLVKIVDVMDSSQQKTFRGHDAPVLSLSFDPKDIFLASASCDGSVRVWQIS------------------------DQTCAISWPLLQKCND-------------------VINAKSICRLAWQPKSGKLLAIPVEKSVKLYRRESWSHQFDLSDNF---ISQTLNIVTWSPCGQYLAAGSINGLIIVWNVETKDCMERVKHEKGYAICGLAWHPTCGRISYTDAEGNLG-LLENVCDPSGKTSSSKVSSRVEK-DYNDLFDGDDMSNAGDFLNDN--AVEIPSFSKGIINDDEDDEDLMMASGRPRQRSHILEDDENSVDISMLKTGSSLLKEEEEDGQEGSIHNLPLVTSQRPFYDGPMPTPRQKPFQSGSTPLHLTHR-FMVWNSIGIIRCYNDEQDNAIDVEFHDTSIHHATHLSNTLNYTIADLSHEAILLACESTDELASKLHCLHFSSWDSSKEWIIDLPQNEDIEAICLGQGWAAAATSALLLRLFTIGGVQKEVFSLAGPVVSMAGHGEQLFIVYHRGTGFDGDQCLGVQLLELGKK-KKQILHGDPLPLTRKSYLAWIGFSAEGTPCYVDSEGIVRMLNRGLGNTWTPICNTREHCKGKSDHYWVVGIHENPQQLRCIPCKGSRFPPTLPRPAVAILSFKLPYCQIATEKGQMEEQFWRSVIFHNHLDYLAKNGYEYEESTKNQATKEQQELLMKMLALSCKLEREFRCVELADLMTQNAVNLAIKYASRSRKLILAQKLSELAVEKAAELTATQVEEEEEEEDFRKKLNAGYSNTATEWSQPRFRNQVEEDAEDSGEADDEEKPEIHKP--GQNSFSKSTNSSDVSAKSGAVTFSSQGRVNPFKVSASSKEPAMSMNSARSTNILDNMGKSSKKSTALSRTTNNEKSPIIKPLIPKPKPKQASAASYFQKRNSQTNKTEEVKEE--NLKNVLSETPAICPPQNTENQRPKTGFQMWLEENRSNILSDNPDFSDEADIIKEGMIRFRVLSTEERKVWANKAKGETASEGTEAKKRKRVVDESDETENQEEKAKENLNLSKKQKPLDFSTNQKLSAFAFKQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PNN9-1", "uniprot_id": "A0A8M9PNN9_DANRE", "id": "A0A8M9PNN9-1", "name": "WD repeat and HMG-box DNA-binding protein 1", "aln": "MPCERKPMRYGHSEGHTDVCFDDQGKCIVTCGSDGDVRIWESLD-DDDPKSINVGEKVYSVALKNGKLVTAVSNNTVQIHTFPDGEPDGILTRFTTNANHVTFNNSGSRVAAGSSDFLVKMVEVADSSQQKTLRGHDAPVLSVALDPSDEFLASSSCDGSVAVWSIE------------------------SQTQVAQWKVLQKSSD-------------------VTNAKSLCRLAWQPRSGKLIAVPVDLTIQLYERNTWTHVSTLSDDL---ITQVVNVVVWSPCGKFLAAGTVGGNLLIWDVEAKLCIDRQKHEKGFTVCGMAWHPSGGRIAYTDTEGCLG-LLEGVSSSSSTVQSSKATAAKEANDYDDLFDEDDDRMLDEDMSDSRSPVKKPIMED---EDDDDDDDLMPATGRPRNRGSFLDDDDNSQDPSSVK-----LDGLPEEGGSSAVLPAVAPVVSRPVYDGPMPTQPQRAFQPGSTPAHLMHR-FMMWNSVGIVRGYNDDQDNAIDVEFHDTAIHHAMHLTNTLGHTMADLSQEAVLLACEGTDELASKIQCLHFSCWDTHKDWMVDLPKGEDVRALCLGQGWAAVATSALMVRLFSIGGVQKEIFSLPGAVVCMAGHGEQLLIAYHRGTGFDGEQALGVQLLQLGRK-KRQVIHGEPLPLSRKSYLAWMGFSAEGTPCCVDSEGVVRLLNRTLGNTWTPVCNTRETCKSKSDHYWVVGVHENPQQLRCIPCKGARFPPTLPRPAVAVLPFNMPYCQTTTEKGQMEEQYWRSMLFHNHYGFLSSSGYEIDSESQAQAEKEQQELLMKMFALSCKLEREFRCVELAELMTHSVVTLAIRYASRSRRMALAQRLSELALEKANQLQEEEQEDE--EPAYQSREYRESNQMNSRQAQQENGCEEEE-VEEEEYPQEEQMDAEESTETRKKFLNPFKKGGKSPEKPSPKPVSREGRVNPFKVSGAGKSSGSPAGQPRTTNVLDSMT-MSRKPAAFSGLSKQSKAPVLKPLAPKPKSKTQATLLQMSASKGNSKKLEDSQSEAEKVKPAPVAATPPVLKENTENKKPKTGFQLWLEENRKSILADNPDF-EEMDVIKEGMGRFRTLSAEERLNWTEKAKGD-----SDPKKRKR---EDEDEEKAAEQMESDEASAKKKKPLDSSA--KLSAFAFNKE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q01454-1", "uniprot_id": "CTF4_YEAST", "id": "Q01454-1", "name": "DNA polymerase alpha-binding protein", "aln": "MVSVIDKLVFDFGG-KTLVSLAPDNNTLCVANKNGLTKILKTNNPEEEPETLDSSKLVSSIKCYSNSHFLMTTMQGDALRYNIDSSQEELLARFALPLRDCCVIHSGKMAVFGGDDLELILLELDDETHKKHAIKIDEQVSQISYNSQMNILAVSMINGKVQIFSLTSTIPNKVHELNDYIVANSYDDTHRDKILSNMMDDIDKDNDNDLSETADPDENNVADPEFCAANRICTRVAWHPKGLHFALPCADDTVKIFSIKGYSLQKTLSTNLSSTKAHFIDLQFDPLRGTYIAAVDLNNKLTVWNWETSEIHYTREFKR--KITNIAWKIQADSKTLDLVLGTWSGSIAIVQNLAESVVSNIPDQSVAESSTKHGLFVDSESDLENLEGND--DINKSDKLFSDITQEANAEDVFTQTHDGPSGLSEKRKYNFEDEEDFIDDDDGAGYISGKKPHNEHSYSRVHKTHSFPISLANTGKFRYMPFSPAGTPFGFTDRRYLTMNEVGYVSTVKNSEQYSITVSFFDVGRFREYHFEDLFGYDLCFLNEKGTLFGQSKTGQIQYRPHDSIHSNWTK----IIPLQAGERITSVAATPVRVIVGTSLGYFRSFNQFGVPFAVEKTS-PIVALTAQNYRVFSVHYS--QFHG---LSYSLSELGTSSKRYYKRECPLPMSLPNINSDMKKDANLDYYNFNPMGIKSLFFSSYG---------DPCIFGSDNTLLLLSKWRSPEESKWLP----------------ILDSNMEIWKMSGGKETTDIHVWPLALAYDTLNCILVKGKHIWPEFP--------------LPLPSEMEIRMPVFVKSKLLEE--------------NKAILNKKNEIGADTEAEEGEEDKEIQ----------------------------------------------------------------------------------IPVSMAAEEEYLRSKVLSELLTDTLENDGEMYGNENEVLAALNGAYDKALLRLFASACSD--------------------------------------------QNVEKALSLAHELKQDRALTAAVKISERAELPSLVKKINNIREARYEQQLK-----------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 94, "similar_positions": 339, "identity": "7.93%" }, { "cls_id": "homologset.agr.SGD:S000006341", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BND5-1", "uniprot_id": "B0BND5_RAT", "id": "B0BND5-1", "name": "U3 small nucleolar RNA-interacting protein 2", "aln": "MNSMSTAVATRKRAKPAPGPGAAPVDGKRRRKVDSAASRGKSKGGGKMNEEISSDSESESLAPRKTEEEEEEELEETAQEKK-------LRLAKLYLEQLRQ---QEEEKAEARAFEEDQVAGRLKEDVLEQRGRLQKLVAKEIQAPAPTD--IRVLRGHQLSITCLVITP---------------DDLAIFSAAKDCTIIKWSVETGRK-----------LHVIPRAKKGTQGQPSGHSSHILCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTG--HRDAVSGLAFRRGTHQLYSTSHDRSVKVWNAAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLVFYG------------------------------------HQGSIDCIHLINEEHMVSGADDGSVALWGLSKKRPLALQREAHGLHGEP---------------------GLEQPFWISSVAALLNTDLVATGSHNACVRLWQCGEGFRQLDPLCDIP-------LVGFINSLKFSSGGDFLVAGVGQEHRLGRWWR-IKEARNSVCIIPLRRVPVSPVAGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WM3-1", "uniprot_id": "U3IP2_MOUSE", "id": "Q91WM3-1", "name": "U3 small nucleolar RNA-interacting protein 2", "aln": "---MSTAVATRKRAKPAPGPGAAPVAGKRRRKVDSAADRGKSKGGGKMNEEISSDSESESLAPRKTEEEEEEELEETAQEKK-------LRLAKLYLEQLRQ---QEEEKAEARAFEEDQVAGRLKEDVLEQRGRLQKSVAKEIQAPAPTD--IRVLRGHQLSITCLVITP---------------DDLAIFSAAKDCTIIKWSVETGRK-----------LHVIPRAKKGAQGQPAGHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTG--HRDAVSGLAFRKGTHQLYSTSHDRSVKVWNAAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLVFYG------------------------------------HQGSIDCIHLINEEHMVSGADDGSVALWGLSKKRPLALQREAHGLHGEP---------------------GLEQPFWVSSVAALLNTDLVATGSHNARVRLWQCGEGFRQLDPLCDIP-------LVGFINSLKFSSAGDFLVAGVGQEHRLGRWWR-IKEARNSVCIIPLRRLPVSPVAGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43818-1", "uniprot_id": "U3IP2_HUMAN", "id": "O43818-1", "name": "U3 small nucleolar RNA-interacting protein 2", "aln": "---MSATAAARKRGKPASGAGAGAGAGKRRRKADSAGDRGKSKGGGKMNEEISSDSESESLAPRKPEEEEEEELEETAQEKK-------LRLAKLYLEQLRQ---QEEEKAEARAFEEDQVAGRLKEDVLEQRGRLQKLVAKEIQAPASAD--IRVLRGHQLSITCLVVTP---------------DDSAIFSAAKDCSIIKWSVESGRK-----------LHVIPRAKKGAEGKPPGHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTG--HRDAVSGLAFRRGTHQLYSTSHDRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLVFYG------------------------------------HQGSIDCIHLINEEHMVSGADDGSVALWGLSKKRPLALQREAHGLRGEP---------------------GLEQPFWISSVAALLNTDLVATGSHSSCVRLWQCGEGFRQLDLLCDIP-------LVGFINSLKFSSSGDFLVAGVGQEHRLGRWWR-IKEARNSVCIIPLRRVPVPPAAGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q06506-1", "uniprot_id": "RRP9_YEAST", "id": "Q06506-1", "name": "Ribosomal RNA-processing protein 9", "aln": "----MSDVTQQKKRKRSKGEVNPSKPTVDEEITDPSSNEDEQLEVSDEEDALESEEEFEGENPADKRRRLAKQYLENLKSEANDILTDNRNAEEKDLNNLKERTIDEYNNFDAGDLDKDIIASRLKEDVAEQQGRVFRYFGDKLLISEAKQSFTRVGENNLTCISCFQPVLNKYTFEESSNGDKNKGRLFAYTVSKDLQLTKYDITDFSKRPKKLKYAKGGAKYIPTSKHEYENTTEGHYDEILTVAASPDGKYVVTGGRDRKLIVWSTESLSPVKVIPTKDRRGEVLSLAFRKNSDQLYASCADFKIRTYSINQFSQLEILYGHHDIVEDISALAMERCVTVGARDRTAMLWKIPDETRLTFRGGDEPQKLLRRWMKENAKEGEDGEVKYPDESEAPLFFCEGSIDVVSMVDDFHFITGSDNGNICLWSLAKKKPIFTERIAHGILPEPSFNDISGETDEELRKRQLQGKKLLQPFWITSLYAIPYSNVFISGSWSGSLKVWKISDNLRSFELLGELSGAKGVVTKIQVVESGKHGKEKFRILASIAKEHRLGRWIANVSGARNGIYSAVIDQTGF------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: :*: * : * . .. .*.:....:. .. :: :.*:.* *. * . ... :: *. :.: . : *::*:: :* :: :* :::* :*.****** **:**: : ...:: . . : ** ..: .*:*: . . ::.:** : *:.: * : ** :*: :. . ** ..:* :* *.****:.:*.*.: :::*.::* . : .:. :*. * .****:.:.***::. * .::.:. : * :* *:**:* * :.**: * ***.*.** *. :****:*::*.* * :**** : :::: *:::*:*:*.:.**.*:**:*: :* ***: ** * ****::*: *: :::. :** .. :::*: .:.:*.:: * ::. : .::* *... ::*.:.:******* :. ***.: : : . ", "identical_positions": 129, "similar_positions": 203, "identity": "22.13%" }, { "cls_id": "homologset.agr.SGD:S000006342", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88298-1", "uniprot_id": "RHD_RAT", "id": "O88298-1", "name": "Blood group Rh(D) polypeptide", "aln": "------------------------------MGSKYPRSLRCCLPLW----AFGLQVTFILLFYFLIGQDPIQA--------------------------------DHK-FMAIYQVIQDLTLVAALGFGFLSSSFRRHGWSSVAFSFFMLALGVQGTILLDYFLNWVL--DWNMIKNPFSPFLSIQRATISTLPLLISAGAVLGKVNLVQLAVMVLVEAMTFGAIRVADKKVFRIEDHIIMMYGHVFGAYFG------LTVAWWLSKSLPRRRHENAQTEKVQMTTSSSLFAMLGTLFLWIFWPSINSALLEG-TKKKN-AVFNTYYALAVSTVT---ATSMSALSHPKGKINMVHIHNAVLAGGVAVGAPSCLISSPWIAMVLGLTAGLISIWGAKCPQVCLSDLL--LNPSGIHYTFGLPGLLGALTYYCLHIIAESRPSN-----------------LWIVTQTITDVGALSFAMAMGMVTGLLTGCLLSVKVWRAPH--AVKYFDDQAFWEFPHLAVEF---------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CF94-1", "uniprot_id": "RHD_MOUSE", "id": "Q8CF94-1", "name": "Blood group Rh(D) polypeptide", "aln": "------------------------------MGSKYPRSLRCCLPLW----ALELQTAFSLLFCFFIPHDTAQV--------------------------------DHR-FMASYQVLRNLTLMAALGFGFLSSSFRRHSWSSVAFNLFMLALGVQGTILLDHFLGQVL--QWNKINN----LSSIQIATMSTLPVLISAGAVLGKVNLVQLTVMVLMEAMAFGAIRFADEKVFKMTEHIIMMHGHVFGAYFG------LTVAWWLSRSLPRRVGENAQTEKVQMATSSSLFAMLGTLFLWIFWPAINSALLEG-TKKRN-AVFNTYYALAVSAVT---ATSMSALSHPQGKINMVHIHNAVLAGGVAVGAPGCLISSPWISMVLGLIAGLISIWGAKCPRACLNHML--QNSSGIHYTFGLPGLLGALTYYCLQIVTEPKSSD-----------------LWIITQTVTHIGALSFAVAMGMVTGLLTGCLLSVRVWRAPH--AAKYFDDQTFWEFPHLAVGF---------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18577-1", "uniprot_id": "RHCE_HUMAN", "id": "P18577-1", "name": "Blood group Rh(CE) polypeptide", "aln": "------------------------------MSSKYPRSVRRCLPLC----ALTLEAALILLFYFFTHYDASLE--------------------------------DQKGLVASYQVGQDLTVMAALGLGFLTSNFRRHSWSSVAFNLFMLALGVQWAILLDGFLSQFP--PGKVVIT----LFSIRLATMSAMSVLISAGAVLGKVNLAQLVVMVLVEVTALGTLRMVISNIFNTDYHMNLRHFYVFAAYFG------LTVAWCLPKPLPKGTEDNDQ-----RATIPSLSAMLGALFLWMFWPSVNSALLRSPIQRKN-AMFNTYYALAVSVVT---AISGSSLAHPQRKISMTYVHSAVLAGGVAVGTSCHLIPSPWLAMVLGLVAGLISIGGAKCLPVCCNRVLGIHHISVMHSIFSLLGLLGEITYIVLLVLHTVWNGN-----------------GMIGFQVLLSIGELSLAIVIALTSGLLTGLLLNLKIWKAPH--VAKYFDDQVFWKFPHLAVGF---------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02161-1", "uniprot_id": "RHD_HUMAN", "id": "Q02161-1", "name": "Blood group Rh(D) polypeptide", "aln": "------------------------------MSSKYPRSVRRCLPLW----ALTLEAALILLFYFFTHYDASLE--------------------------------DQKGLVASYQVGQDLTVMAAIGLGFLTSSFRRHSWSSVAFNLFMLALGVQWAILLDGFLSQFP--SGKVVIT----LFSIRLATMSALSVLISVDAVLGKVNLAQLVVMVLVEVTALGNLRMVISNIFNTDYHMNMMHIYVFAAYFG------LSVAWCLPKPLPEGTEDKDQ-----TATIPSLSAMLGALFLWMFWPSFNSALLRSPIERKN-AVFNTYYAVAVSVVT---AISGSSLAHPQGKISKTYVHSAVLAGGVAVGTSCHLIPSPWLAMVLGLVAGLISVGGAKYLPGCCNRVLGIPHSSIMGYNFSLLGLLGEIIYIVLLVLDTVGAGN-----------------GMIGFQVLLSIGELSLAIVIALMSGLLTGLLLNLKIWKAPH--EAKYFDDQVFWKFPHLAVGF---------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JI14-1", "uniprot_id": "RHCL2_DANRE", "id": "Q8JI14-1", "name": "Ammonium transporter Rh type C-like 2", "aln": "-----MGNCFGSRG-ICDRPK--------------NTNIRLSLPAV----CFVWQVSMIILFGVFVRYNEEADTNWVYTKKE-----------------KNITSDIENDFYFRYPSFQDVHVMIFVGFGFLMTFLKRYSFGAVGFNFLIAAFGLQWALLMQGWFSPLG-DDGKIKIG----IENLINADFCVASCLIAYGAVLGKVSPVQLLVMTLFGITLYAVEEFIILRVLNAKDAGGSMVIHTFGAYYG------LSISRVLYRPNLNKSKHMNG-----SVYHSDVFAMIGTLFLWMFWPSFNSAICNHGDGQHR-AAINTYLALASTVLT---TVAISSMFEKTGKLDMVHIQNSTLAGGVAVGTAAEFMLMPYGSLIVGFFCGIISTLGYIYLTPFLEERLKIQDTCGIHNLHAMPGVIGGIVGAISAAAASKEVYGDLGLKN-IFSIEGSNVTRLPTVQGGYQAAALCVALCFGIGGGTFVGLVLKLPIWGDPA--DEHCFNDEMYWEVPEDEESIIPPVLSYNNHMIPNNKHEEMRETNFAEQS----------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TTF1-1", "uniprot_id": "A0AB32TTF1_DANRE", "id": "A0AB32TTF1-1", "name": "", "aln": "MLRMTFLAPFASRSRDCATRKRDATETQRDEQTQTQTDTQRNLPCAPDRSAGGVKIAMIILFGVFIRYDEESDSHWIETRKK-----------------NNISTDLENDFYYRYPSFQDVHVMIFVGFGFLMTFLKRYSFGSVGFNFLIAAFGIQWALLMQGWFHSFDKEDLKIKIG----VENLINADFCVAGCLIAYGACLGKVSPVQLMVLTLFGVTLYAVEEYIILYVLHVRDAGGSMVIHTFGAYYG------LTISWVLYRPFLSQSNHLQR-----SVYHSDVFAMIGTLFLWMFWPSFNSAIADHGDGQHR-AAINTYLSLAASVLT---TFALSSLSKKYGKLDMVHIQNATLAGGVAMGTASEFMITPYGSLIVGFCSGIVSTLGYVFLTPLMEKTLKIQDTCGVHNLHAMPGVIGGIVGAVTAACASESVYGHEGLIN-MFGFEG-KVNRTASVQGGYQAAGIFVAIAFGLVGGALVGGILKLPIWGDPT--DSNCFDDDIYWEVPEEEDENIPAFGHQNMHHVERTPDAHHRSHV---------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9QXP0-1", "uniprot_id": "RHCG_MOUSE", "id": "Q9QXP0-1", "name": "Ammonium transporter Rh type C", "aln": "--------------------------------MAWNTNLRGRLPIT----CLILQVTMVVLFGVFVRYDIQADAHWWLEKKR-----------------KNISSDVENEFYYRYPSFQDVHAMVFVGFGFLMTFLQRYGFSAVGFNFLLAAFGIQWALLMQGWFHYFE--EGHIVLS----VENIIQADFCVASSCVAFGAVLGKVSPMQLLIMTFFQVTLFTVNEFILLNLIEAKDAGGSMTIHTFGAYFG------LTVTWILYRKNLDQSKQRQS-----SVYHSDLFAMIGTLFLWIYWPSFNSASSFHGDAQHR-AALNTYLSLAASVLT---TVTVSSIVHKKGKLDMVHIQNATLAGGVGVGTAAEMMLTPYGALIVGFFCGIFSTLGFAYLTPFLESRHRIQDTCGIHNLHGIPGIIGGIVGAVTAAYSSPDVYGEPGIVH-SFGFGSYKMDWNKRMQGRSQIFGLLLSLAMALVGGIIVGFILKLPFWGQAA--DENCFEDSIYWEVHEEVNTVYIPEDLAHKHSTSLVPAMPLVLPTTSASIVPPVPPTPPVSLATSAPSAALVH-----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBD6-1", "uniprot_id": "RHCG_HUMAN", "id": "Q9UBD6-1", "name": "Ammonium transporter Rh type C", "aln": "--------------------------------MAWNTNLRWRLPLT----CLLLQVIMVILFGVFVRYDFEADAHWWSERTH-----------------KNLS-DMENEFYYRYPSFQDVHVMVFVGFGFLMTFLQRYGFSAVGFNFLLAAFGIQWALLMQGWFHFLQ--DRYIVVG----VENLINADFCVASVCVAFGAVLGKVSPIQLLIMTFFQVTLFAVNEFILLNLLKVKDAGGSMTIHTFGAYFG------LTVTRILYRRNLEQSKERQN-----SVYQSDLFAMIGTLFLWMYWPSFNSAISYHGDSQHR-AAINTYCSLAACVLT---SVAISSALHKKGKLDMVHIQNATLAGGVAVGTAAEMMLMPYGALIIGFVCGIISTLGFVYLTPFLESRLHIQDTCGINNLHGIPGIIGGIVGAVTAASASLEVYGKEGLVH-SFDFQGFNGDWTARTQGKFQIYGLLVTLAMALMGGIIVGLILRLPFWGQPS--DENCFEDAVYWEMPEGNSTVYIPEDPTFKPSGPSVPSVPMVSPLPMASSVPLVP-----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BUX5-1", "uniprot_id": "RHBG_MOUSE", "id": "Q8BUX5-1", "name": "Ammonium transporter Rh type B", "aln": "----------------------------MARVPR---HRRLVLPLL----CLLFQGATALLFAIFVRYNHETDAALWHWGN---------------------HSNVDNEFYFRYPSFQDVHVMVFVGFGFLMVFLQRYGFSSVGFTFLVASLTLQWATLLQGFLHSFH--GGHIHVG----VESLINADFCAGAVLISFGAVLGKTGPAQLLLMALLEAVLFSVNEFILLSLLGVRDAGGSMTIHTFGAYFG------LFLSWVLYRSQLEKSRHRQS-----SVYNSDLFAMIGTIFLWVFWPSFNSAPTALGDGQHR-TVVNTYYSLTASTLS---TFALSALVSGDGRLDMVHVQNAALAGGVVVGTSSEMMLTPFGALAAGFLAGTVSTLGYKFFTPILESRFKLQDTCGVHNLHGMPGVLGAILGVVVAALATHEAYG-DGLQS-VFPLIA-KGQRSATSQAVYQLFGMFVTLVFASVGGSLGGLLLRLPFLDSPP--DSQCFEDQVYWEVPGEQETETQRPLRGGESDTRA-------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68FT6-1", "uniprot_id": "RHBG_RAT", "id": "Q68FT6-1", "name": "Ammonium transporter Rh type B", "aln": "----------------------------MARIPR---HRRLVLPLL----CLLFQGATSLLFAIFVRYNHETDAALWHWGN---------------------HSNVDNEFYFRYPSFQDVHVMVFVGFGFLMVFLQRYGFSSVGFTFLVATFTLQWATLLQGFLHSFH--GGHIHIG----VESLINADFCAGAVLISFGAVLGKTGPAQLLLMALLEAVLFSVNEFILLSLLGVRDAGGSMTIHTFGAYFG------LFLSRVLYRSQLEKSRHRQT-----SVYNSDLFAMIGTIFLWVFWPSFNSAPTALGDGQHR-TVVNTYYSLTASTLS---TFALSALVSGDGRLDMVHIQNAALAGGVVVGTASEMMLTPFGALAAGFLAGTVSTLGYKFFTPILESRFKLQDTCGVHNLHGMPGLLGAILGVLVAALATHEAYG-DGLQT-VFPLIA-KGQRSATSQAMYQLFGMFVTLVFASVGGSLGGLLLKLPFLDSPP--DSQCFEDQVYWEVPGEQEAETQRPLRTEEPDTQA-------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H310-1", "uniprot_id": "RHBG_HUMAN", "id": "Q9H310-1", "name": "Ammonium transporter Rh type B", "aln": "----------------------------MAGSPSRAAGRRLQLPLL----CLFLQGATAVLFAVFVRYNHKTDAALWHRSN---------------------HSNADNEFYFRYPSFQDVHAMVFVGFGFLMVFLQRYGFSSVGFTFLLAAFALQWSTLVQGFLHSFH--GGHIHVG----VESMINADFCAGAVLISFGAVLGKTGPTQLLLMALLEVVLFGINEFVLLHLLGVRDAGGSMTIHTFGAYFG------LVLSRVLYRPQLEKSKHRQG-----SVYHSDLFAMIGTIFLWIFWPSFNAALTALGAGQHR-TALNTYYSLAASTLG---TFALSALVGEDGRLDMVHIQNAALAGGVVVGTSSEMMLTPFGALAAGFLAGTVSTLGYKFFTPILESKFKVQDTCGVHNLHGMPGVLGALLGVLVAGLATHEAYG-DGLES-VFPLIA-EGQRSATSQAMHQLFGLFVTLMFASVGGGLGGLLLKLPFLDSPP--DSQHYEDQVHWQVPGEHEDKAQRPLRVEEADTQA-------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QUT0-1", "uniprot_id": "RHAG_MOUSE", "id": "Q9QUT0-1", "name": "Ammonium transporter Rh type A", "aln": "--------------------------------------MRFKFPLM----AISLEVAMIVLFGLFVEYETPQNASQKNASHQNASQQ-----------GNTSSSAKKDQFFQLYPLFQDVHVMIFVGFGFLMTFLKKYGFSGVGFNLFLAALGLQWGTIMQGLLHSHG---KEFHFG----IYNMINADFSTATVLISFGAVLGKTSPIQMLIMTILEIAVFAGNEYLVTELFEASDTGASMTIHAFGAYFG------LAVAGVLYRPGLRCEHPNDE-----SVYHSDLFAMIGTLFLWIFWPSFNSAIADPGDHQYR-AIVNTYMSLAACVIT---AYALSSLVERRGRLDMVHIQNATLAGGVAVGTCADMEIPLYAAMTIGSIAGIISVLGYKFFSPLLANKLMIHDTCGVHNLHGLPGVFGGLASIVAISWG-----------------------MSTAS-MAMQAAALGSSIGSAIVGGLLTGLILKLPIWNQPP--DEYCYDDSVSWKVPKFRELDNRFFQHANHNHVEHEV-----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TNK7-1", "uniprot_id": "RHAG_RAT", "id": "Q7TNK7-1", "name": "Ammonium transporter Rh type A", "aln": "--------------------------------------MRFKFSLI----ALSLEVVMIVSFALFVEYETSQNGSQKSASQQNASQQNAAAQQNASQQGNASSPAKEDQFFQLYPLFQHVHVMIFVGFGFLMTFLKKYGFSGVGFNLFLAALGLQWGTIVQGLLHSHG---LKFPFR----IKNMINADFSTATVLISFGAVLGKTSPIQMIIMTILEIAVFAGNEHLVTEIFKASDTGASMTIHAFGAYFG------LAVAGVLYRSGLKHGHPNEE-----SVYHSDLFAMIGTLFLWMFWPSFNSAIAQPENNQYR-AIVNTYMSLAACVIT---AYALSSLVERRGRLDMVHIQNATLAGGVAVGTCADMEIPLYFAMTIGSIAGIISVLGYKFLSPLLAHKLMIHDTCGVHNLHGLPGVFGGLASIVAISWG-----------------------KSTVSTMAMQATALGSSIGSAIVGGLVTGLILKLPVWNQPP--DEYCFDDSVSWKVPKYRELDNYFFQHVTHNHVEHEV-----------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02094-1", "uniprot_id": "RHAG_HUMAN", "id": "Q02094-1", "name": "Ammonium transporter Rh type A", "aln": "--------------------------------------MRFTFPLM----AIVLEIAMIVLFGLFVEYETDQTVLEQ---------------------LNITKPTDMGIFFELYPLFQDVHVMIFVGFGFLMTFLKKYGFSSVGINLLVAALGLQWGTIVQGILQSQG---QKFNIG----IKNMINADFSAATVLISFGAVLGKTSPTQMLIMTILEIVFFAHNEYLVSEIFKASDIGASMTIHAFGAYFG------LAVAGILYRSGLRKGHENEE-----SAYYSDLFAMIGTLFLWMFWPSFNSAIAEPGDKQCR-AIVNTYFSLAACVLT---AFAFSSLVEHRGKLNMVHIQNATLAGGVAVGTCADMAIHPFGSMIIGSIAGMVSVLGYKFLTPLFTTKLRIHDTCGVHNLHGLPGVVGGLAGIVAVAMG-----------------------ASNTS-MAMQAAALGSSIGTAVVGGLMTGLILKLPLWGQPS--DQNCYDDSVYWKVPKTR------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53390-1", "uniprot_id": "MEP3_YEAST", "id": "P53390-1", "name": "Ammonium transporter MEP3", "aln": "----------------------------------MARGDGHLWTET----YDSSTVAFMILGAALVFFMVPGLG------------------------------------FLYSGLARRKSALALIWVVIMATLVGILQWYFWGYSLAFSKTATNNKFIGN--LDSFGFRNVYGKISDDSTYPELIYAIFQMMFMCVALSIIAGATAERGKLFPHMVFLFVFATLVYCPITYWIWAPGGWAYQWGVLDWAGGGNIEILSAVAGFVYSYFLGRRKENLLIN---FRPHNVSMVTLGTSILWFGWLLFNAASSLSPNMRSVYAFMNTCLSATTGGMT---WCLLDYRSEK--KWSTVGLCSGIICG-LVAATPSSGCITLYGSLIQGIIAGVVCN-----FATKIKYYLKVDDSLDLLAEHGIAGVVGLIFNALFAADWVIGMDGTTKHKGGWLTHNWKQMYIQIAYIGASAGYCAVVTAIICFVLGKIPGVHLRVTEEAEALGLDEDQIGEFAYDYVEVRRDYYQWGVDTDALHTTCNGANSASETNPTEDSQNSSLSSATVSGQNEKSNNPKLHHAKEA-------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VFA9-1", "uniprot_id": "Q9VFA9_DROME", "id": "Q9VFA9-1", "name": "Ammonium transporter", "aln": "-----------------------------MNNGTVGAPRNHSNYVIPGLYDLSVEDTNWVLTSSFIIFTMQTGFG-----------------------------------MLESGCVSIKNEVNIMMKNVIDIVLGGFTYWLFGYGMSFGRGPLSNPFIAIGDFLLDP-PVGDALMG------QIFAAFLFQLSFATTATTIVSGAMAERCNFKAYCLFSFLNTAVYCIPAGWVWGEHGFLNKLGAVDIAGSGPVHLIGGASAFASAAMLGPRLGRYSEGYDPLPLGNPVNACMGLFVLWWGWLAFNSGSTYGVSGAKWQYAARAAVMTMMGSFGGGFTSSIYSFWRHGGGMDIMDLINGVLGSLVSITAG-CFLYRAWEALVIGAIGSLFCVLAMP-----LFDRMGVDDPVGASAVHGVCGIWG-VIAVGLFADNPIPLDTTNGRSGLFKGGGWYLLGIQTLSALCLACWGVCSTFLLLYVINKIIPIRMDPHEELLGADLTEHRIRHSQIGLSRAISALAPIKVDLKDIAGIQPIGINPGHERSIDQLRAAEDKLQQWQSYLEQVSGSRANVKMDAGQSHADINFKPRTAGNVFNRRIPARKSISGGLYRSNNSELPVIGSVMGQKPEKDPNFAWVD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : .: . : . : . . : : .: * : : . . . .. . : . :* .** * .*:. .: . . : .. : . : : : :: * . .. . ..: *: * : : . . : . ", "identical_positions": 9, "similar_positions": 59, "identity": "1.41%" }, { "cls_id": "homologset.agr.SGD:S000006344", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K0X0-1", "uniprot_id": "A0A0G2K0X0_RAT", "id": "A0A0G2K0X0-1", "name": "Tafazzin family protein", "aln": "---------------------------------------------------------------------------------------------------------------------MPLHVKWPFP--AVPRLTWTLASSVVMGLVGTYSCFWTKYMNHLTVYNKEVLYELIENRGPATPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVPVCR-GDGVYQKGMDFILEKLNHGD------------------------------WVHIFPEGKVN-----MSSEFLRFKWVGIGRLIAECHLNPIILPLWHVGMNDVLPNSP------PYFPR-FGQKITVLIGKPFSTLPVLERLRAEN-----------------------KSAVEMRKALTDFIQEEFQRLKMQAEQLHNHFQPGR----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WF0-1", "uniprot_id": "TAZ_MOUSE", "id": "Q91WF0-1", "name": "Tafazzin", "aln": "---------------------------------------------------------------------------------------------------------------------MPLHVKWPFP--AVPRLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNKEVLYELIENRGPATPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVPVCR-GDGVYQKGMDFILEKLNHGD------------------------------WVHIFPEGKVN-----MSSEFLRFKWG-IGRLIAECHLNPIILPLWHVGMNDVLPNSP------PYFPR-FGQKITVLIGKPFSTLPVLERLRAEN-----------------------KSAVEMRKALTDFIQEEFQRLKMQAEQLHNHFQPGR----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16635-3", "uniprot_id": "TAZ_HUMAN", "id": "Q16635-3", "name": "Tafazzin", "aln": "---------------------------------------------------------------------------------------------------------------------MPLHVKWPFP--AVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPATPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVPVCR-GDGVYQKGMDFILEKLNHGD------------------------------WVHIFPEGKVN-----MSSEFLRFKWG-IGRLIAECHLNPIILPLWHVGMNDVLPNSP------PYFPR-FGQKITVLIGKPFSALPVLERLRAEN-----------------------KSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QCP6-1", "uniprot_id": "TAZ_DANRE", "id": "F1QCP6-1", "name": "Tafazzin", "aln": "---------------------------------------------------------------------------------------------------------------------MPLEVTWPFP--QCPRLGWRISSRVVMGMVGSYSYLWTKYFNSLMVHNQDVLLNLVDERPQDTPLITVCNHQSCMDDPHIWGVLKFRQLWNLNKMRWTPTASDICFTREFHSSFFSRGKCVPVVR-GDGVYQKGMDFLLERLNQGE------------------------------WIHIFPEGRVN-----MSGEFMRIKWG-IGRLIAECSLHPIILPMWHIGMNDVLPNET------PYIPR-VGQRITVLVGKPFTVRHLVNALRAEN-----------------------TNPTEMRKTVTDYIQDEFRSLKAQAEALHHRLQNHT----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V6G5-1", "uniprot_id": "TAZ_DROME", "id": "Q9V6G5-1", "name": "Tafazzin", "aln": "MFMVVCSNLRRPGHVGAASAARNINWLISEGYTPPIRAMARPYVQAPEARPVPDERYPGSQQDRKDIATQTVRSSKPKDLRPPSPPTPSQTLNSSSLPPPMSDQDADPSLDVPTGVAMPYNIDWIFPRLRNPSKFWYVVSQFVVSAVGIFSKVVLMFLNKPRVYNRERLIQLITKRPKGIPLVTVSNHYSCFDDPGLWGCLPLGIVCNTYKIRWSMAAHDICFTNKLHSLFFMFGKCIPVVR-GIGVYQDAINLCIEKAALGH------------------------------WIHVFPEGKVN-----MDKEELRLKWG-VGRIIYESPKIPIILPMWHEGMDDLLPNVE------PYVIQ-RGKQVTLNVGQPLDLNDFILDLKKRQ-----------------------VPEPTARKLITDKIQEAFRDLRAETEKLHRERN-------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06510-1", "uniprot_id": "TAZ_YEAST", "id": "Q06510-1", "name": "Tafazzin", "aln": "---------------------------------------------------------------------------------------------------------------MSFRDVLERGDEFLEAYPRRSPLWRFLSYSTSLLTFGVSKLLLFTCYNVKLNGFEKLETALERSKRENRGLMTVMNHMSMVDDPLVWATLPYKLFTSLDNIRWSLGAHNICFQNKFLANFFSLGQVLSTERFGVGPFQGSIDASIRLLSPDDTLDLEWTPHSEVSSSLKKAYSPPIIRSKPSWVHVYPEGFVLQLYPPFENSMRYFKWG-ITRMILEATKPPIVVPIFATGFEKIASEAVTDSMFRQILPRNFGSEINVTIGDPLN-DDLIDRYRKEWTHLVEKYYDPKNPNDLSDELKYGKEAQDLRSRLAAELRAHVAEIRNEVRKLPREDPRFKSPSWWKRFNTTEGKSDPDVKVIGENWAIRRMQKFLPPEGKPKGKDD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . : : .* . . * .. * .: *:** ** * .*** :*. * . . :**: * :*** .:: : ** *: :.. * * * :* .:: :. .. *:*::*** * :. . :** : *:* *. **::*:: *::.: .: . : *..:.: :*.*: .: : . *. :: :: . :: :.. * .. ", "identical_positions": 47, "similar_positions": 85, "identity": "9.51%" }, { "cls_id": "homologset.agr.SGD:S000006345", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QWT9-1", "uniprot_id": "KIFC1_MOUSE", "id": "Q9QWT9-1", "name": "Kinesin-like protein KIFC1", "aln": "----------------------------MDVQAQRPPLLEVKRNVELKAALVKSSSRVPLSASRLKRGPDQMEDALEPAKKRTRVMGAVTKVDTSRPRGPLLSTVSQTQGHTAAQKGPKKTGPRGCSAIGTV-LRSQKPVPAAPAQKPGTSTAPVVVG-KRAGKRPAWDLKGQLCDLNEELKRYREKTQTLE----LENRGLREQLREVQEQATTLGTERNTLEGELASVRSRAEQDQQRLETLSARVLELEEC-------------LGTRERLLQELQGERLQLQEERSTLSTQLEEQERRFQATEAALSSSQEEVVCLRQ----------------------------KTEAQVTLLAEQGDRLYGLEMERRRLHNQLQELKGNIRVFCRVRPVLEGESTPSPGFLVFPPGPAGPSDPPTGLSLSRSDDRRSTLTGAPAPTVRHDFSFDRVFPPGSKQEEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPRGDPQLEGLIPRAMRHLFSVAQEMSGQGWTYSFVASYVEIYNETVRDLLATGPRKGQGGECEIR---RASPGSEELTVTNARYVPVSCEKEVEALLHLAHQNRAVAHTAQNKRSSRSHSVFQLQISGEHAARGLQCGAPLNLVDLAGSERLDPGLHLGPGERDRLRETQAINSSLSTLGLVIMALSNKES---HVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANKK--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PUA5-1", "uniprot_id": "E9PUA5_MOUSE", "id": "E9PUA5-1", "name": "Kinesin-like protein", "aln": "----------------------------MDVQAQRK-GREGKRNVELKAALVKSSSRLPLSASSLKRGPDQMEDALEPAKKRTRVMGAVTKVDTSRPRGPLLSTVSQTQGHNAAQKGPKKTGPGGCSAVGTV-LRSQKPAPAAPA-KPGTSTAPVVVG-KRAGKRPAWDLKGQLCDLNEELKRYREKTETLE----LENRGLREQLREVQEQATTLGTERNTLEGELASVRSRAEQDQQRLETLSARVLELEEC-------------LGTRERLLQELQGERLQLQEERSTLSTQLEEQERRFQATEAALSSSQEEVVCLRQ----------------------------KTEAQVTLLAEQGDRLYGLEMERRRLHNQLQELKGNIRVFCRVRPVLEGESTPSPGFLVFPPGPAGPSDRPTGLSLSRSDDRRSTLTGAPAPTVRHDFSFDRVFPPGSKQEEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPRGDPQLAGLIPRAMRHLFSVAQEMSGQGWTYSFVASYVEIYNETVRDLLATGPRKGQGGECEIR---RASPGSEELTVTNARYVPVSCEKEVEALLHLAHQNRAVAHTAQNKRSSRSHSVFQLQISGEHAARGLQCGAPLNLVDLAGSERLDPGLPLGPGERDRLRETQAINSSLSTLGLVIMALSNKES---HVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANKK--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XI63-1", "uniprot_id": "KIFC1_RAT", "id": "Q5XI63-1", "name": "Kinesin-like protein KIFC1", "aln": "----MRGRGSRDTGTQSAAFASRPVRTTVDMQAQRAPLMEVKRNLELSTTLVKSSSRLPLPGSRLKRGPDQMEDGLEPAKKRTRGMGTVTKVDTSRPRGPPLSAVS-----TAAQKGPRKTGPRGCSAVGPV-LRNQKPAPAAPAQKPGTSTAPAVAG-KKPGKRPAWDLKGQLCDLHEELKQYREKTQTLD----RENQGLREQLREVQEQATTLGTERNTLEEELASVRRRAEQSQQKLETLGARVLELEEC-------------LGTKERLVQELQTERLQLQEERSTLSTQLEEREREFQASEAALSSSRAEVLCLRQ----------------------------KTAAQVTLLAEQGDRLYGLEMERRRLHNQLQELKGNIRVFCRVRPVLEGESTPSPGFLVFPPGPAGPSDPPTRLCLSRSDDRRSTLTRAPAAATRHDFSFDRVFPPGSKQEEVFEEISMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPRGDPQLEGLIPRAMRHLFSVAQEMSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGGDCEIR---RAGPGSEELTVTNARYVPVSCEKEVEALLHLAQQNRAVARTAQNERSSRSHSVFQLQISGEHAARGLQCGAPLNLVDLAGSERLDPGLTLGPGERDRLRETQAINSSLSTLGLVIMALSNKES---HVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANKK--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BW19-1", "uniprot_id": "KIFC1_HUMAN", "id": "Q9BW19-1", "name": "Kinesin-like protein KIFC1", "aln": "------------------------------MDPQRSPLLEVKGNIELKRPLIKAPSQLPLSGSRLKRRPDQMEDGLEPEKKRTRGLGATTKITTSHPRVPSLTTVPQTQGQTTAQKVSKKTGPRCSTAIATG-LKNQKPVPAVPVQKSGTSGVPPMAGGKKPSKRPAWDLKGQLCDLNAELKRCRERTQTLD----QENQQLQDQLRDAQQQVKALGTERTTLEGHLAKVQAQAEQGQQELKNLRACVLELEER-------------LSTQEGLVQELQKKQVELQEERRGLMSQLEEKERRLQTSEAALSSSQAEVASLRQ----------------------------ETVAQAALLTEREERLHGLEMERRRLHNQLQELKGNIRVFCRVRPVLPGEPTPPPGLLLFPSGPGGPSDPPTRLSLSRSDERRGTLSGAPAPPTRHDFSFDRVFPPGSGQDEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPGGDPQLEGLIPRALRHLFSVAQELSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGGECEIR---RAGPGSEELTVTNARYVPVSCEKEVDALLHLARQNRAVARTAQNERSSRSHSVFQLQISGEHSSRGLQCGAPLSLVDLAGSERLDPGLALGPGERERLRETQAINSSLSTLGLVIMALSNKES---HVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANRK--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LUU7-1", "uniprot_id": "Q1LUU7_DANRE", "id": "Q1LUU7-1", "name": "Kinesin-like protein", "aln": "-------------------------------------------------MNKENTSRLPVMSGKRAHTNSTDGEQQQPAQKKMR----KVEVEPSQ-RFRPAASVAPPRRPVAVKAPVKPLRPTGAATVAAAPARGDQRRPVAAVAKATAAVS----------RRPGWDLKGKVSDMEAKVQNYQSKVKTVN----QENECLKDSIAKVQRRTADIEQENNGLRRRLG----DCEKELVKLATVKDDLEHTTKE-------------RDGLQKDLSKLTEEHKVLEGLRDHLESELRNIQTQLAIQTSALGRCQDSLKESQE----------------------------LARNLEETVARQREELHLGEMERRKLHNTIQELKGNIRVFCRVRPLLTGNQSDILHIQLPPHDN-------KALTLAKMEESHTGRT--TDTQKSYNFSFDRVFGPRSSQSEVFEEISLLVQSALDGYNVCCFAYGQTGSGKTFTMEGGEQ--EELWGVIPRAVQQIFKSAKALSEQGWQYSFTASFVEIYNETLRDLLYKG-KPNKRPEHEIR---KVS--NNEITVTNLTYQKVNNEDEVHNLIMLANQNRSTARTCMNDHSSRSHSVFQLDIEGENTARDSKCKSMLCLVDLAGSERVQKSQSQG----ERFKEMTAINSSLTNLGIVIAALANKDS---FVPYRNSKLTYLLQNCLGGNSKTLMFANISPEEESFSESLNSLRFASKVNDCVIGTASANKK--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20480-1", "uniprot_id": "NCD_DROME", "id": "P20480-1", "name": "Protein claret segregational", "aln": "----MESRLPKPSGLKKPQMPIKTVLPTDRIRAGLGGGAAGAGAFNVNANQTYCGNLLPPLSRDLNNLPQVLERRGGGARAASPEPMKLGHRAKLRRSRSACDINELRGNKRTAAAPSLPSIPSKVSRLGGALTVSSQRLVRPAAPSSITATAVKRPPVTRPAPRAAGGAAAKKPAGTGAAASSGAAAAAPKRIAPYDFKARFHDLLEKHKVLKTKYEKQTEDMGELESMPQQLEETQNKLIETESSLKNTQSD-------------NECLQRQVKQHTAKIETITSTLGRTKEELSELQAIHEKVKTEHAALSTEVVHLRQRTE---------------------ELLRCNEQQAAELETCKEQLFQSNMERKELHNTVMDLRGNIRVFCRIRPPLESEENRMCCTWTYHDES--------------TVELQSIDAQAKSKMGQQIFSFDQVFHPLSSQSDIFEMVSPLIQSALDGYNICIFAYGQTGSGKTYTMDGVPES----VGVIPRTVDLLFDSIRGYRNLGWEYEIKATFLEIYNEVLYDLLSNE-----QKDMEIR---MAKNNKNDIYVSNITEETVLDPNHLRHLMHTAKMNRATASTAGNERSSRSHAVTKLELIGRHAEKQEISVGSINLVDLAGSESPKTS--------TRMTETKNINRSLSELTNVILALLQKQD---HIPYRNSKLTHLLMPSLGGNSKTLMFINVSPFQDCFQESVKSLRFAASVNSCKMTKAKRNRYLNNSVANSSTQSNNSGSFDK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17119-1", "uniprot_id": "KAR3_YEAST", "id": "P17119-1", "name": "Kinesin-like protein KAR3", "aln": "MESLPRTPTKGRSTQHLSTPSPKNDILAMNGHKRRNTTTPPPKHTLLKPQRTDIHRHSLASQSRISMSPNRELLKNYKGTANLIYGNQKSNSGVTSFYKENVNELNRTQAILFEKKATLDLLKDELTETKEKINAVNLKFETLREEKIKIEQQLNLKNNELISIKEEFLSKKQFMNEGHEIHLKQLAASNKKELKQMENEYKTKIEKLKFMKIKQFENERASLLDKIEEVRNKITMNPSTLQEMLNDVEQKHMLEKEEWLTEYQSQWKKDIELNNKHMQEIESIKKEIENTLKPELAEKKKLLTEKRNAYEAIKVKVKEKEEETTRLRDEVALKQKTNLETLEKIKELEEYIKDTELGMKELNEILIKEETVRRTLHNELQELRGNIRVYCRIRPALKNLENSDTSLINVNEFD------------DNSGVQSMEVTKIQNTAQVHEFKFDKIFDQQDTNVDVFKEVGQLVQSSLDGYNVCIFAYGQTGSGKTFTMLNPGD------GIIPSTISHIFNWINKLKTKGWDYKVNCEFIEIYNENIVDLLRSDNNNKEDTSIGLKHEIRHDQETKTTTITNVTSCKLESEEMVEIILKKANKLRSTASTASNEHSSRSHSIFIIHLSGSNAKTGAHSYGTLNLVDLAGSERINVSQVVG----DRLRETQNINKSLSCLGDVIHALGQPDSTKRHIPFRNSKLTYLLQYSLTGDSKTLMFVNISPSSSHINETLNSLRFASKVNSTRLVSRK------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . . : : . . : . . :. .: * : . : .. :* : : .: .: : : * : *: *** : :*:*****:**:** * . . : *.**::* . : ::*: :. *:**:**** :* ***********:** . *:** :: :*. . ** *.. . ::***** : *** . . :: .: ::* : . : :: *. *:.* *. *.:*****:: :.: * :: . . : ******** . . *: * ** **: * ** ** : :. .:*:******:** .* *.:* *** *:** .. ..*:::*****:.**. : . . ", "identical_positions": 116, "similar_positions": 124, "identity": "14.97%" }, { "cls_id": "homologset.agr.SGD:S000006347", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M947-1", "uniprot_id": "RRP15_RAT", "id": "Q5M947-1", "name": "RRP15-like protein", "aln": "MAAAVQDSRVNPGGKLKRSPKKKKKMKKVAKAAVSKLEDELKDSSGGEGSCESEMDD--SDDGAAEADSEDNVESCEEENEVAAESSAGTNSGWADAMAKILNKKTPKSKPTILTKNKELEKEKEKLKQERLEKRKQIDKKREWEMLCRVKPDVIKDKEAERNLQRIATRGVVQLFNAVQKHQRNVDEKVKEVGGSIRKRAKLMSTVSKKDFISVLRGMDGAS-ENSSAGKSPKARQTEVKSE-------EGPGWKILRDDFMMGASMKDWDKESE-----GEEPADGQAGSASH---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CYX7-1", "uniprot_id": "RRP15_MOUSE", "id": "Q9CYX7-1", "name": "RRP15-like protein", "aln": "MAAAVQDSRVSPGEILKRSPKKKKKMKMVAKAAASKLEDEVKDSSDGEGSCDSEMDH--SDDGAAEADSEDNVESCEEDNEDAAESSAGTNSGWADAMAKILNKKTPKSKATILTKNKELEKEKEKLKQERLEKRKQLDKKREWEMLCRVKPDVVKDKEAERNLQRIATRGVVQLFNAVQKHQRNVGEKVKEAGGSVRKRAKLMSTVSKKDFISVLRGMDGTS-RNSPAGKSPKARQTEVKSE-------ESPGWKILRDDFMMGASMKDWDKESE-----GEEPAGGRAEAAASR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3B9-1", "uniprot_id": "RRP15_HUMAN", "id": "Q9Y3B9-1", "name": "RRP15-like protein", "aln": "MAAAAPDSRVSEEENLKKTPKKK--MKMVTGAVASVLEDEATDTSDSEGSCGSEKDHFYSDDDAIEADSEGDAEPCDKENENDGESSVGTNMGWADAMAKVLNKKTPESKPTILVKNKKLEKEKEKLKQERLEKIKQRDKRLEWEMMCRVKPDVVQDKETERNLQRIATRGVVQLFNAVQKHQKNVDEKVKEAGSSMRKRAKLISTVSKKDFISVLRGMDGSTNETASSRKKPKAKQTEVKSE-------EGPGWTILRDDFMMGASMKDWDKESD-----GPDDSRPESASDSDT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZV20-1", "uniprot_id": "RRP15_DANRE", "id": "Q7ZV20-1", "name": "RRP15-like protein", "aln": "MAALAVKPHVVVED---------------GNDDVS----EVSISNDEESGADSDHEG-----ADAENSGDEDGKSDEEQNEEN------PNAGWAEAMAKVLGKKTPDTKPSILLKNKQLDKIKEKEKKERLEKKKQLDKKRAWENICREKPDVVQDREHERNLQRVATRGVVQLFNALKNHQKNVNERIKEVGGSERKKSKILSSVSKKDFIDVLRGTDVAV-----------KKEKEIKAE-------KSS-WSVLKDDFMMGASMKDWDKERDEDGGGGEEDEREPAQEYSSESD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFE6-1", "uniprot_id": "RRP15_DROME", "id": "Q9VFE6-1", "name": "RRP15-like protein", "aln": "-MALLTEKRVKKTH-----------------APASDSSPEESDSEGSQNSASEAEGNAGWADSIQKVLKTTKPKTQKKTVLARAKKSQAAVRFQKDAANKKPGFDFEIEKADVKEEDEGDNHEDEKPQASALDATLTKQQRKNVPLQLRVKP-SFRDMERERTLRKVATRGVVQFFNAVRIQQKDLQQQLEEAGPLDSRQDAVLNNINKRKFLDVLMSGKRAKSTPVDNAVKKEEQETDDDDEDKGSSGKKKSEWSVLREDFMTNKKIKHWDEEDDDEE--GHNDEADDSDYDDGEE-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06511-1", "uniprot_id": "RRP15_YEAST", "id": "Q06511-1", "name": "Ribosomal RNA-processing protein 15", "aln": "---MGSKHRVDTKD-------------------KKRTRKNAEFGREKRNSGNQELSNEPEKDTIMEGDEAEEDEQNSSSDESSKIIDNEQSDAEEDDDEEEEDDDFPRKKKSKNSKHDDGSTGFSAAVNAILSSHLKAYDRK--DPIMARNKKVLKQSESEK-LEYKAKKALLAEKKKLLGKARKTDIIPIASG---EDRSENIRKVLEKETALRKIAQKGAVKLFNAILATQVKTEKEVSEN-----------LSEIKNKEEKKELITEVSKEKF------LDLVKAAAGSDNE---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* . : ... . : . : .. : : . . * :.. . . *. .: : .:: * *: *. *.:.:: : : : :. * : : .: ::. . . : :.: . : . :::. :.. .:* : : ", "identical_positions": 9, "similar_positions": 68, "identity": "3.02%" }, { "cls_id": "homologset.agr.SGD:S000006348", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BHY2-1", "uniprot_id": "NOC4L_MOUSE", "id": "Q8BHY2-1", "name": "Nucleolar complex protein 4 homolog", "aln": "----------MERHPASASSRQELGRLLEAVLTSRGQANAVFDILAVLQ-SEEPEEIEEGVRTCSRLFGTLLEREELFVGSLPSEDTALAGSQGATYKYKVWIRHRYHSCCNRLEELLAHPTFQVKELALKTLMKFVQLEGAKPLEKPQWESHYLFPRTLFRAVVGGLLTP-----EDDHSLLISHFCEYLEYDDIRYHTMQVATSIMARATSQ---QPEVSLTLWNNAFTLLSAVSLPLQECELTNFYVKHAQTSDKWKVVHLKEHKKAFQEMWLGFLK--HKLPLSLYKKVLVAMHDSILPHLAQPTLMIDFLTSACDVG------GAISLLALNGLFILIHKHNLEYPDFYQKLYGLLDPSIFHVKYRARFFHLADLFLSSSHLPAYLVAAFAKRLARLALTAPPEALLMVLPLICNLLRRHPACRVMVHRPQGP-----------------ELDADPYDPTEKDPARSRALESCLWELQTLQQHYHPEVSKAASVINQVLSVPEVSIAPLLELTAYEIFEQDLKKKMPESVPLEFIPAKGLLGRQDDLCTQFFCLS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5I0I8-1", "uniprot_id": "NOC4L_RAT", "id": "Q5I0I8-1", "name": "Nucleolar complex protein 4 homolog", "aln": "----------MERQPASTGSRQELGRLLEAVLSNRGRANAVFDILAVLQ-SEDPEEIKEGVRTCSRLFGTLLEREELFVGSLPCEDMALAGSQGATYKYKVWMRHRYHSCCNRLEELLTHPSFQVKELALETLMKFVQLEGAKPLEKPQWESHYLFPRTLFRAVVGGLLTP-----EDDHSLLISQFCEYLEYDDIRYHAMQVATSILARATSR---QPEVSLTFWNNAFTLLSAVNLPLQEHELTNFYVKHAQTSSKWKVVHLKEQRKAFQEMWLGFLK--HKLPLSLYKKVLVAMHDSILPHLAQPTLMIDFLTSACDVG------GAISLLALNGLFILIHKHNLEYPDFYQRLYGLLDPSIFHVKYRARFFHLADLFLSSSHLPAYLVAAFAKRLARLALTAPPEALLMVLPLICNLLRRHPACRVMVHRPQGP-----------------ELDADPYDPTEKDPARSRALESCLWELQTLQQHYHPEVSRAASVINQALSVPEVSIAPLLELTAYEIFEQDLKKMMPESVPLEFIPAKGLLGRQDDLCTQFFCLS--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BVI4-1", "uniprot_id": "NOC4L_HUMAN", "id": "Q9BVI4-1", "name": "Nucleolar complex protein 4 homolog", "aln": "----------MEREPGAAGVRRALGRRLEAVLASRSEANAVFDILAVLQ-SEDQEEIQEAVRTCSRLFGALLERGELFVGQLPSEEMVMTGSQGATRKYKVWMRHRYHSCCNRLGELLGHPSFQVKELALSALLKFVQLEGAHPLEKSKWEGNYLFPRELFKLVVGGLLSP-----EEDQSLLLSQFREYLDYDDTRYHTMQAAVDAVARVTGQ---HPEVPPAFWNNAFTLLSAVSLPRREPTVSSFYVKRAELWDTWKVAHLKEHRRVFQAMWLSFLK--HKLPLSLYKKVLLIVHDAILPQLAQPTLMIDFLTRACDLG------GALSLLALNGLFILIHKHNLEYPDFYRKLYGLLDPSVFHVKYRARFFHLADLFLSSSHLPAYLVAAFAKRLARLALTAPPEALLMVLPFICNLLRRHPACRVLVHRPHGP-----------------ELDADPYDPGEEDPAQSRALESSLWELQALQRHYHPEVSKAASVINQALSMPEVSIAPLLELTAYEIFERDLKKKGPEPVPLEFIPAQGLLGRPGELCAQHFTLS--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4VBT2-1", "uniprot_id": "NOC4L_DANRE", "id": "Q4VBT2-1", "name": "Nucleolar complex protein 4 homolog", "aln": "--MAPSGDSNVKEHNNQVSYKKAINTKTDLILQNKKHANDIFDVIEYLQ-SEKEKEIIFATNACSKIFCELIERGDLFVGELPKEEDLAQGDRSAEEKYHIFMRHRYNSCVELMLENVSHESFQVKETSLCAVMKFVATEGKHPLQNLDWSEHYNFPRELIQALVEHLLSE-----KEDMSLLISRFQEFMEKDDVRYYVMSSVRYSTATVMERN--KKAVIPVFQNNVFNLLTTINIPNQASEMTNFLVQQQSKHDDWKAAKLKEHKRAFEQMWLLFLR--YKLPGSMYKKILVILHESILPQMSDPKLMMDFLSAAYDIG------GAISLSALNGLFVPIHEHNLDYPDFYKKLYNLLDPSIFHVKYRARFFHLANIFLSSTHLPVYLVAAFVKRLARLSLTAPPTALLILLPFICNLIRRHPSCRVLIHRPSAAD----------------EPCDDPYVMEEEDPAQCHALESSLWEIKTLQNHHHPDVSKAATMINEPLSAQEEDISELLELTTFELMERELKGE-KKTVPLEFDMATDLLKSSREVLGVHFTLE--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06512-1", "uniprot_id": "NOC4_YEAST", "id": "Q06512-1", "name": "Nucleolar complex protein 4", "aln": "MVLLISEIKDIAKRLTAAGDRKQYNSIIKLINELVIPEN----VTQLEE-DETEKNLRFLVMSLFQIFRKLFSRGDLTLPSSKK-------STLEKEQFVNWCRKVYEAFKTKLLAIISDIPFET-SLGLDSLDVYLQLAELESTHFASEKGAPFFPNKTFRKLIIALWSSNMGEIEDVKSSGASENLIIVEFTEKYYTKFADIQYYFQSEFNQLLEDPAYQDLLLKNVGKWLALVNHDKHCSSVDADLEIFVP-NPPQAIENESKFKSNFEKNWLSLLN--GQLSLQQYKSILLILHKRIIPHFHTPTKLMDFLTDSYNLQSSNKNAGVVPILALNGLFELMKRFNLEYPNFYMKLYQIINPDLMHVKYRARFFRLMDVFLSSTHLSAHLVASFIKKLARLTLESPPSAIVTVIPFIYNLIRKHPNCMIMLHNPAFISNPFQTPDQVANLKTLKENYVDPFDVHESDPELTHALDSSLWELASLMEHYHPNVATLAKIFAQPFKKLSYNMEDFLDWNYDSLLNAESSRKLKTLPTLEFEAFTNVFDNEDGDSEASSQGNVYLPGVAW", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W4R1-1", "uniprot_id": "Q9W4R1_DROME", "id": "Q9W4R1-1", "name": "CCAAT-binding factor domain-containing protein", "aln": "--MKPLTVKVNDDTGKSLAKKKLQSKANSLLNAEQVDIKTLKGFVQLLKNTPDNMPAGEVMNTLEVIFKNLLKRKAIDG----------------TEKQGLKIKKLYEETWLLLIENLLVDSQCS--VAVKVCMQLIKVEAKHPIAPNKG-----WPTYWIRGMLETLINS-----DTTPTTALANYGKYCKNLDVLEITLTQLKSLVPDEDFKD------SPIKAMNFLSIVNLLDMGKSVLSTADYHVESAKKQTFNYELN----RKRLNNLWATIMAKGNEVDEKLHRQILVVLLERVINHLNDPIQLTDFLMDSLHQFD-----GPIALLALQGIFTLMQKQNITYPDVYEKLYNMFYPRMFHNKYKARLFYLADIFLTSTHLPENLVAAFVKRLARLALQSPTEDAVIMIRFVCNLLLRHTGLQKLIRASHAV-----------------DEVSDPYNQTETDPVKSEAINSSLWEITLLQKHVVPEVANAARFINSSLPVMEFDLAPLLDRKECNIFDDELQSKAKQFA-LNYERPTNLALPKNQFVTKYWDLI--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: . . : : . : : :* *:.* : : :: *. : : . .: : .. . :* :: :: * . . : :. . : : : * . : :. : : :: * :: :: . ::.:*: : . :: :: * : *** : . * :.: **:*:* ::. *: **:.* :** :: * ::* **:**:* * ::**:*:**. ***:* *:****:* :*. : :: :: **: :*. ::: . : **: * ** .*::*.***: * .* *:*: * .: . : . .: :*: . .::: : . *:: .: ", "identical_positions": 68, "similar_positions": 138, "identity": "11.97%" }, { "cls_id": "homologset.agr.SGD:S000006349", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49088-1", "uniprot_id": "ASNS_RAT", "id": "P49088-1", "name": "Asparagine synthetase [glutamine-hydrolyzing]", "aln": "MCGIWALFG--------------SDDCLSVQCLSAMKIAHRGPDAFRFENVNGYTNCCFGFHRLAVVDPLFGMQPIRVRKYPYLWLCYNGEIYNHKALQQRFEFE---YQTNVDGEIILHLYDKGGIEKTICMLDGVFAFILLDTANKKVFLGRDTYGVRPLFKALTEDGFLAVCSEAKGLVSLKHSTTPFLKVEPFLPGHYEVLDLKPNGKVASVEMVKYHHCTDEPLHAIYDSVEKLFPGFEIETVKNNLRILFNNAIKKRLMTDRRIGCLLSGGLDSSLVAASLLKQLKEAQVP---------------------------YALQTFAIGMEDSPDLLAARKVANYIGSEHHEVLFNSEEGIQSLDEVIFSLETYDITTVRASVGMYLISKYIRKNTDSVVIFSGEGSDELTQGYIYFHKAPSPEKAEEESERLLKELYLFDVLRADRTTAAHGLELRVPFLDHRFSSYYLSLPPEMRIPKDG----------IEKHLLRETFEDSN------LLPKEILWRPKEAFSDGITSVKNSWFKILQDFVEHQVDDAMMSEASQKFPFNTPQTKEGYYYRQIFEHHYPGR-ADWLTHYWMP--KWINATDPSARTLTHYKSTAKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61024-1", "uniprot_id": "ASNS_MOUSE", "id": "Q61024-1", "name": "Asparagine synthetase [glutamine-hydrolyzing]", "aln": "MCGIWALFG--------------SDDCLSVQCLSAMKIAHRGPDAFRFENVNGYTNCCFGFHRLAVVDPLFGMQPIRVRKYPYLWLCYNGEIYNHKALQQRFEFE---YQTNVDGEIILHLYDKGGIEKTICMLDGVFAFILLDTANKKVFLGRDTYGVRPLFKAMTEDGFLAVCSEAKGLVSLKHSTTPFLKVEPFLPGHYEVLDLKPNGKVASVEMVKYHHCTDEPLHAIYDSVEKLFPGFDLETVKNNLRILFDNAIKKRLMTDRRIGCLLSGGLDSSLVAASLLKQLKEAQVQ---------------------------YPLQTFAIGMEDSPDLLAARKVANYIGSEHHEVLFNSEEGIQALDEVIFSLETYDITTVRASVGMYLISKYIRKNTDSVVIFSGEGSDELTQGYIYFHKAPSPEKAEEESERLLKELYLFDVLRADRTTAAHGLELRVPFLDHRFSSYYLSLPPDMRIPKNG----------IEKHLLRETFEDCN------LLPKEILWRPKEAFSDGITSVKNSWFKILQDYVEHQVDDEMMSAASQKFPFNTPKTKEGYFYRQIFERHYPGR-ADWLTHYWMP--KWINATDPSARTLTHYKSAAKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08243-1", "uniprot_id": "ASNS_HUMAN", "id": "P08243-1", "name": "Asparagine synthetase [glutamine-hydrolyzing]", "aln": "MCGIWALFG--------------SDDCLSVQCLSAMKIAHRGPDAFRFENVNGYTNCCFGFHRLAVVDPLFGMQPIRVKKYPYLWLCYNGEIYNHKKMQQHFEFE---YQTKVDGEIILHLYDKGGIEQTICMLDGVFAFVLLDTANKKVFLGRDTYGVRPLFKAMTEDGFLAVCSEAKGLVTLKHSATPFLKVEPFLPGHYEVLDLKPNGKVASVEMVKYHHCRDVPLHALYDNVEKLFPGFEIETVKNNLRILFNNAVKKRLMTDRRIGCLLSGGLDSSLVAATLLKQLKEAQVQ---------------------------YPLQTFAIGMEDSPDLLAARKVADHIGSEHYEVLFNSEEGIQALDEVIFSLETYDITTVRASVGMYLISKYIRKNTDSVVIFSGEGSDELTQGYIYFHKAPSPEKAEEESERLLRELYLFDVLRADRTTAAHGLELRVPFLDHRFSSYYLSLPPEMRIPKNG----------IEKHLLRETFEDSN------LIPKEILWRPKEAFSDGITSVKNSWFKILQEYVEHQVDDAMMANAAQKFPFNTPKTKEGYYYRQVFERHYPGR-ADWLSHYWMP--KWINATDPSARTLTHYKSAVKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49089-1", "uniprot_id": "ASNS1_YEAST", "id": "P49089-1", "name": "Asparagine synthetase [glutamine-hydrolyzing] 1", "aln": "MCGIFAAFR-----------HEDVHRYKPKALQLSKRIRHRGPDWS-GNAIK--NSTIFVHERLAIVGVESGAQPITSSDG-EYMLCVNGEIYNHIQLREECADY--EFGTLSDCEPIIPMYLKHDID-APKYLDGMFAWTLYDAKQDRIVAARDPIGITTLYMGRSSASPKTVYFAS----ELKCLTDDCDTITAFPPGHVYDSKTDKITRYFTPDWLDEKRIPSTPIDYM------------------AIRHSLEKAVRKRLMAEVPYGVLLSGGLDSSLIASIAARETAKATNDVEPSTYDSKARHLAGIDDDGKLHTAGWTSLHSFAIGLPNAPDLQAARKVAKFIGSIHHEHTFTLQEGLDALDDVIYHLETYDVTTIRASTPMFLLSRKIKA-QGVKMVLSGEGSDEIFGGYLYFAQAPSAAEFHTESVQRVKNLHLADCLRANKSTMAWGLEARVPFLDREFLQLCMNIDPNEKMIKPK-------EGRIEKYILRKAFDTTGEPDAKPYLPEEILWRQKEQFSDGVG---YSWIDGLKDTAEAVISDEMFASPKAEWGSDIPTTKEAFWYRLKFDALFPQKTVADTVMRWIPKADWGCAEDPSGRYAQIHEKHIE-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q7KTW9-1", "uniprot_id": "Q7KTW9_DROME", "id": "Q7KTW9-1", "name": "Asparagine synthetase [glutamine-hydrolyzing]", "aln": "MCGIFAIFSRDGEPIPTQILHGSKHSLRELAYRQSGKHRHRGPDST-GVYVNSLEGVAMIHERLRIIGVEMGDQPFVSEDG-NLILVANGEIYNYLELSAEIAKKRGSYNPMSDCHVILELYQDYGKD-LLQYITGMFAFALYDRKTKEVLLARDPFGIIPMYVGEDASG--NLWVAS----EMKCLVDTCSKVETFTPGEARFGKVGDFKTCWQFQQSWIKEVPTQTCELS------------------LLRANLEFAVRSHLQCDVQMGALLSGGVDSSLIASIAT----KIMRERDPN-----------------------FRLKTFSVGLRDAPDFQAARSVAKYIDSDHKEIIFEIDEALDGIRDIIYHLETYDVTTVRCSLPMLLLARYIKS-TGIKMILSGEGADEIFGGYLYFHKAPSYNDFHEELVKRVRQLHLSDCLRANKVAMAKGVELRVPFLDTGFVNHVMQIRPEDKIPGPLNKFGEVQQKRLEKYVLRAAFADN-------YLPDEVLWRQKEQFSDGVG---YDWIDSIRRVATSHVSDQEFSAAALRFPFNTPTTKEAFYYRCIFAEQFPGESAARTVVRWVPRLDWGCPEDPSGRAQAVHQVNKN-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:* * . : : ***** :: . : ..** ::. * **: . * ******: : . : . * . *: :* . . : : *:**: * * ..:. .**. *: .:: . . : : :* . .: .* **. . : :. . . :* :: *::.:* : * *****:****:*: : *::*::*: ::**: ***.**..*.* * * * :*.::.: ::*: *****:**:*.* * *::: *: . :::****:**: **:** :*** . . * : :::*:* * ***:: : * *:* ****** * . :.: *: :: :**::** :* :*.*:*** ** ****: .*:. :: . :.* :: . .: : * ***.::** * :* . . *:* .* . ***.* :: : ", "identical_positions": 145, "similar_positions": 156, "identity": "23.24%" }, { "cls_id": "homologset.agr.SGD:S000006351", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BVA5-1", "uniprot_id": "LDAH_MOUSE", "id": "Q8BVA5-1", "name": "Lipid droplet-associated hydrolase", "aln": "MASEVEEQIPVREEFFLCGGVETKIIKCGPWTNLFEKQDVSKPKQLIFIIPGNPGYSAFYVPFAKALYTLMKSRFPVWIISHAGFSVTPKDKKVLAAPQEESNAQKIEDVYGLNGQIEHKIAFLRAHVPKDVKLILIGHSVGTYMTLHVMKR-VLELPVAHAFLLFPTIERMSESPNGK---FATPFLCQFRYLLYATSYLLFKPCP-EVIKSFIIQKLMGQMNIKLELP---LTDILQPFCLANAAYLGSQEMVQIVK------RDDDIIKEFLPKLKFYYGKTDGWCPVKYYEDMKKDFPEGNIYLCEKGIPHAFVLDFSQEMATIVAEWINNRPPRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5HZX7-1", "uniprot_id": "LDAH_RAT", "id": "Q5HZX7-1", "name": "Lipid droplet-associated hydrolase", "aln": "MASEVEDGVPVHEEFFLCGGVETQIIKCGPWTNLFDKQGVSKPKHLIFVIPGNPGLSPFYVPFAKALYSLVKGHFPVWIISHAGFCLTPKDKKILTAPQE-PNAQEIEDIYGLNGQIEHKIAFLRAHVPKDVKLIFIGHSVGSYIALHVMNR-APELPVVHTFLLFPTIERMSESPNGK---FATPFLCRFRYMLYAASYLIFKPCP-EMIKSFIVQKVLEKMSFKSELR---LTDLLQPFCLANAAYLGGQEMIHVVK------RDDGIIKELLPKLTFYYGKTDGWCPVNYYEDMKRDFPEANLHLCEKGIPHAFVLGFSQEMAAMVADWINNRLPKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H6V9-1", "uniprot_id": "LDAH_HUMAN", "id": "Q9H6V9-1", "name": "Lipid droplet-associated hydrolase", "aln": "MDSELKEEIPVHEEFILCGGAETQVLKCGPWTDLFHDQSVKRPKLLIFIIPGNPGFSAFYVPFAKALYSLTNRRFPVWTISHAGHALAPKDKKILTTSED-SNAQEIKDIYGLNGQIEHKLAFLRTHVPKDMKLVLIGHSIGSYFTLQMLKR-VPELPVIRAFLLFPTIERMSESPNGR---IATPLLCWFRYVLYVTGYLLLKPCP-ETIKSLLIRRGLQVMNLENEFS---PLNILEPFCLANAAYLGGQEMMEVVK------RDDETIKEHLCKLTFYYGTIDPWCPKEYYEDIKKDFPEGDIRLCEKNIPHAFITHFNQEMADMIADSLKDDLSKM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W0H3-1", "uniprot_id": "LDAH_DROME", "id": "Q9W0H3-1", "name": "Lipid droplet-associated hydrolase", "aln": "----------MQEAYVNINSIPTHIFTWGRWI-----EETITEKEIVICITGNPGLPGFYTEFAGTLQKELG-DLPVWVIGHAGHDDPPE-----ASIREVPQLSGNEELFNLDGQIRHKIAFIEKYVPSDVKIHLIGHSIGAWMILQLLENERIRSRIQKCYMLFPTVERMMESPNGW---VFTKVAMPLYSVFGYIFFSFFNFLP-VWLRLMLIQIYFLIFSIPRQFLG-TALKYSKPSVAEKVVFLADDEMARVRG------IQREIVEQNLDLLKFYYGTTDGWVPISYYDQLKKDYPKVDAQLDTKKIDHAFVLRHSQPMAVIVRDMIQQHRRV-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06522-1", "uniprot_id": "YP147_YEAST", "id": "Q06522-1", "name": "Lipid droplet-associated triacylglycerol lipase", "aln": "----------MTVKEYTKSKLPCSILNIKPTVT-----KSGEDAPLLVWIPGNPGLLYYYQEMLHHLH-LKHPDWEILGISHAGMT---------------LNAHSNTPIFSLQDQVDHQVEVINNFSCKNRKIIIMGHSVGAYIVQKVCLSNKLVGSVQKVGLVTPTVMDIHTSEMGIKMTAALRYIPPLAHVVSLFSYIFFYWILSEGFSRFIIDKFMGCGSTGYQAVLSTRIFLTHRQFVRQSLGLAAQEMEEITTNWEFQDRFINYCEENGISIWFLFSSNDHWVSGKTRSHLSDYYKD---KVKQERLKIDVTDKIPHSFVVKHAEYAINAFF--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ::. ::. *.**** :* : * : *.*** : ::.*:.*: *:: .:. . .: *: ::***:*::: :: : : :: **: : * * : :. : :: : ::: : . : . : *. :** .: :: : * :.. * * . . ..:. : . : : : . : :. : : ", "identical_positions": 29, "similar_positions": 85, "identity": "8.53%" }, { "cls_id": "homologset.agr.SGD:S000006358", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62993-1", "uniprot_id": "GRB2_HUMAN", "id": "P62993-1", "name": "Growth factor receptor-bound protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHP----------------------WFFGKIPRAKAEEMLSK-------------------QRHDGAFLIR-----ESESAPGDFSLSVKFGNDVQHFKVLRDG-----------AGKYFLWVVKFNSLN-ELVDYHRSTSVSRNQ-------------------QIFLRDIEQVPQ-------QPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62994-1", "uniprot_id": "GRB2_RAT", "id": "P62994-1", "name": "Growth factor receptor-bound protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHP----------------------WFFGKIPRAKAEEMLSK-------------------QRHDGAFLIR-----ESESAPGDFSLSVKFGNDVQHFKVLRDG-----------AGKYFLWVVKFNSLN-ELVDYHRSTSVSRNQ-------------------QIFLRDIEQVPQ-------QPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60631-1", "uniprot_id": "GRB2_MOUSE", "id": "Q60631-1", "name": "Growth factor receptor-bound protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHP----------------------WFFGKIPRAKAEEMLSK-------------------QRHDGAFLIR-----ESESAPGDFSLSVKFGNDVQHFKVLRDG-----------AGKYFLWVVKFNSLN-ELVDYHRSTSVSRNQ-------------------QIFLRDIEQMPQ-------QPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91X43-1", "uniprot_id": "SH319_MOUSE", "id": "Q91X43-1", "name": "SH3 domain-containing protein 19", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNIMNTEQSQNTIVSRIKAFEGQTNTEIPGLPKKPEIIPRTIPPKPAVSSGKPLVAPKPAANRASGEWDTWAENRLKVTSREGLTPYSSPQEAGITPVTKPELPKKPTPGLTRSVNHETSGGRPMAESPDTGKKIPTPAPRPLLPKKSASTDAPPYPSIPPKLVSAPPRLSVASQAKAFRSLGEGLPSNPPVPAPQSKALGDIDLISFDDDVLPT-SGSPAEEPTGSETVLDPFQLPTKTEATKERAVQPAPTRKPTVIRIPAKPGKCLHEEPQSPPPLPAEKPVGNTHSAVSGRPSHSDRTRNPELEQASESGGLVQGPPRLPPRPVHGKVIPVWRPPPKGAPERPPPPKLPASKSSNKNLPFNRSSSDMDLQKKQSHFVSGLSKAKSQIFKNQDPVLPPRPKPGHPLYRKYMLSVPHGIANEDIVSRNPTELSCKRGDVLVILKQAENNYLECQRGEGTGRVHPSQMKIVTPLDERPRGRPNDSGHSQKPVDSGAPHAVALHDFPAEQADDLSLTSGEIVYLL-EKIDAEWYRGKCRNQTGVFPANYVKVIVDIPEGRSGKRESFSSHCAKGPRCVARFEYIGDQKDELSFSEGEVIILTEYVNEEWGRGEIRDRSGIFPLNFVELVGDHPTSGANILSTKVPPKTKNEDPGSNS------QDSSPPGEWCKALHSFTAETSEDLPFKRGDRILILERLDSDWYRGRLHDREGIFPAVFVQPCPAEAKGVASAIPKGRKVKALYDFLGENEDELSFKAGDVITELEPIDDAWMRGELMGRAGMFPKNYVQFLQVS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A086-1", "uniprot_id": "A0A8I6A086_RAT", "id": "A0A8I6A086-1", "name": "", "aln": "MAEGRRREDEEEELRERRELGGPRRARSRALPGHSAADRNERHKPEHRSSSQGPLSSIRAVIKRSSRTCIQSELHRDRRRPEITIVAAEPLRPASWFPGAPPPGLGFPSTPVGGSWRPNDLVPAELPPSYEQVIKEINQVQVNSTNNNNAAATPRSTITSATQTDFPEEIDGDPPPTLQAPLKPLQSSPAASAGNLPPGVAPLIVFDICEEQNCPEKPSATRCPVPRPRSKTNLRPVARDAHSKEKNVPKSPVTPREDWPPQCLLDSTCNLDSQSVMNIMNTEQSQNTIISRIKAFEGQTSTEIPGPPKKPEIIPRTVPPKPAVSSGKPLVAPKPAANRASGEWDSWAENRLKVTSREGLTSYSSPQEAGITPVTKPELPKKPTPGLTRTANHETSGGRPMAESPDAGKKIPTPAPRPLLPKKSASPDAPPYPSVPPKLVSVPPRLSVTSQAKAFRLPGEGPPSNPPVPAPQSKALGDIDLISFDDDVLPT-SGSPAEEPIGSEMVLDPFQLPTKTEATKERAVQPVPTRKPTVIRIPAKPGKCLHEEPQSPPPLPAEKPVGNTYSVASGRLSNSDRTRNPDLEQASESGSLVQGPPRLPPRPVHGKVIPVWRPPPKGAPERPPPPKLSATKSSNKNLPFNRSSSDMDLQRKPCHLASGLSKAKSQVFKNQDPVLPPRPKPGHPLYRKYMLSVPHGIANEDIVSQNPTELSCKRGDVLVILKQAENNYLECRRGEGTGRVHPSQMKIVTPLDEHPRSRPNGSGHTQKPVDSGAPHAVALHDFPAEQADDLSLTSGEIVYLL-EKIDAEWYRGKCRNQTGIFPANYVKVVVDIPEGRSGKRESFSSHCAKGQRCIARFEYIGDQKDELSFSEGEVIVLTGYVNEEWGRGEIRDRTGIFPLNFVELVEDHPMSGANILSTKVPPKTKNEDPGSNSQIPALKQDSSPPGEWCRALHSFTAETSEDLAFKRGDRILILERLDSDWYRGRLHGKEGIFPAVFVQPCPAEAKSVASTMRKGKKVKALYDFVGENEDELSFKAGDVITELEPVDDDWMRGELMGKAGIFPKNYVQFLQVS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5HYK7-1", "uniprot_id": "SH319_HUMAN", "id": "Q5HYK7-1", "name": "SH3 domain-containing protein 19", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNIMNTEQSQNSIVSRIKVFEGQTNIETSGLPKKPEITPRSLPPKPTVSSGKPSVAPKPAANRASGEWDSGTENRLKVTSKEGLTPYPPLQEAGSIPVTKPELPKKPNPGLIRSVNPEIPGRGPLAESSDSGKKVPTPAPRPLLLKKSVSSENPTYPSAPLKPVTVPPRLAGASQAKAYKSLGEGPPANPPVPVLQSKPLVDIDLISFDDDVLPTPSGNLAEESVGSEMVLDPFQLPAKTEPIKERAVQPAPTRKPTVIRIPAKPGKCLHEDPQSPPPLPAEKPIGNTFSTVSGKLSNVERTRNLESNHPGQTGGFVRVPPRLPPRPVNGKTIPTQQPPTKVPPERPPPPKLSATRRSNKKLPFNRSSSDMDLQKKQSNLATGLSKAKSQVFKNQDPVLPPRPKPGHPLYSKYMLSVPHGIANEDIVSQNPGELSCKRGDVLVMLKQTENNYLECQKGEDTGRVHLSQMKIITPLDEHLRSRPNDPSHAQKPVDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLL-EKIDTDWYRGNCRNQIGIFPANYVKVIIDIPEGGNGKRECVSSHCVKGSRCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGRTGIFPLNFVEPVEDYPTSGANVLSTKVPLKTKKEDSGSNS------QVNSLPAEWCEALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQDREGIFPAVFVRPCPAEAKSMLAIVPKGRKAKALYDFRGENEDELSFKAGDIITELESVDDDWMSGELMGKSGIFPKNYIQFLQIS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q06449-1", "uniprot_id": "PIN3_YEAST", "id": "Q06449-1", "name": "[PSI+] inducibility protein 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSASLINRSLTNIRTELDFLKGSNVISNDVYDQINKSLPAKWDPAN--------------------------------------------------------------------------------APRNASPASLEYVEALYQFDPQQDGDLGLKPGDKVQLL-EKLSPEWYKGSCNGRTGIFPANYVKPAFSG-----------------------------------------------------------------------------SNGPSNLPPPPQYKAQELQQIPTQ--------------------NSAASSYQQQPFPPPSTN-------------------------YYQQPQQQPQ----------------QAPPPQQQQQQQQHQSSHSHLKSFGSKLGNAAIFGAGASIGSDIVNNIF---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . ::* . .:*.:. *: : :* *: . :**:.. ..: *.:* **:: * *. ..:. . . : . : : : : .: : :: : : . :. . . * . : : : : ", "identical_positions": 14, "similar_positions": 56, "identity": "1.3%" }, { "cls_id": "homologset.agr.SGD:S000006360", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NYN7-1", "uniprot_id": "S22A6_DANRE", "id": "Q6NYN7-1", "name": "Solute carrier family 22 member 6", "aln": "---------------------------MAFSDLLEQVGSTGRFQVLHVTLLSMPILMMASHNLLQNFVAAVPPHHCQPHANLSMSS-TDAVDVLRATVPLGLNGKLERCKRYTTPQWQILSLNTSESLWDESMAETETQSCEDG-------------------------------------WFYNMTEMSSTIITEWDLVCDY-------------RALKQMSQTTYMGGVLVGAIVFGGLSDRFGRRVLLLISNLMMAIGGTCVAFSTSFTMFCVFRVCCGMALSGLVLNSFSLIVEWIPTRVR---TVVGTG-TGYCYTTGQLILAAVAYCIRDWRWLTLAVSLPFYVSFLYSWWFLESARWLVLTKNPEQAVKNLKTVARINGRSAEGDKIDLEMLQESMKKEMACSKGSYSALDLLRTS---TMRTITICLSAVWFSTSFAYYGLSMDLQKFGVSIYLIQIIFGAVDIPAKIIVT--ICMSMLGRRPSQCGALV---LAGIMILINLLVPSDLQMLRTSLAVIGKGCLAASFNCCYLYAGELYPTVIRQSGMGWVSMMARFGAMVAPMVLLLGDDYPWIPGFIYGGAPIVSGIFAFFLPETLSQPLPDTIQDIDDRGLARTNSK--RLPEKLDLAMKDPSCVLLKESV-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6YVM2-1", "uniprot_id": "A0A8M6YVM2_DANRE", "id": "A0A8M6YVM2-1", "name": "", "aln": "--------------------------MIDFTQILSSVGEFGAFQKRLLVAVCLPNIFTAFHMFGQVFTAISFPHYCNSSWILRQAPNLTEEKQLNLTVPLDSKGQYESCKMFTPVEMDIEDI--------EHYGINTTTSCIDG-------------------------------------WVYKAPKDSSTLITEFDLVCEN-------------KVYSEASQSIYMAGLLVGALLFGPMADKYGRRFATLLSLFLQFLSGVGVAFSPNIYVYIALRFVVGTTISGISINTFVLGTEWCGSAKR---ALFTIL-SHCFFAIGLMLLSGVAYGIRNWRVLQLVLSAPVGLFFIYYWILPESARWLLTQGKLDSAKREILKAARINGRKVS------ENLLDKMEAENTAK--SSTMIDLFRVG---YLRKRALIMCYMWFVTSLVYYGVSLNVGNFGLDIYLTQLIFGMAEFPARLSCF--PLIQRFGRRICQSVVLL---LGGTACLIIPAIPAKYPIVVTVIAVIGKFSLAASFSIVYVYTAELYPTVVRQNGVGLNSMCARVAGILAPLIGLLDVYHHAIPMIIYGSLPFVGGALTFLLPETLNTDLQDHTDIPADESMTVTEVKLERWGRRRGWDRERSTSQDFKSGRL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PJE3-1", "uniprot_id": "A0A8M9PJE3_DANRE", "id": "A0A8M9PJE3-1", "name": "", "aln": "--------------------------MGNYDEDTAFLGQTGPFFIRLFCLLNLIYISTGLHGLYIVFVAASPAHRCRVDVNLTEDWLEASAPTETLSNGDLQVSQCWRYSLQTLTNLSGQGYSPGQ----INITDIPRERCEDG-------------------------------------WVYSADVYHSTIVSEWDLVCDS-------------EWRVPLASSTLYMGYLLGSIVSGQLSDRFGRKKVLFGSLAAEALLMFAQSFSPSWLIFCVLYFFIGAFQISLYITAFVLGNEVLSGSLR---VLFTTLGAFLHYCVGYMLLPWVAFAIRHWRTLLRVLSGLTVVYIPLWWLIPESPRWLLSQGHVQESEAILRDAARKNRVPAP-----EVIFKQSQIKEAAFQKSKYSALDVLRTS---NIRRTTFMCLLLWMAINIGYFGLSLNTTNLSGDPFLNCFLSAVTEVPAYIVST--FLLKSCPRRPVLSAFLV---IGGGFLLLVQLIPDRLQTLALALEMAGKFGFTMSFTVVYIYTAELYPTVLRNLGMGMCSSAARIGSITAPYIIFLGTFNRHLPYVLMGSLTITASLANLFLPETFGKVLPENLEQMQKSRSFP--------GRDKQSVEDGGGGEKMREEKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06451-1", "uniprot_id": "TPO3_YEAST", "id": "Q06451-1", "name": "Polyamine transporter 3", "aln": "MNRQESINSFNSDETSSLSDVESQQPQQYIPSESGSKSNMAPNQLKLTRTETVKSLQDMGVSSKAPVPDVNAPQSSKNKIFPEEYTLETPTGLVPVATLHSIGRTSTAISRTRTRQIDGASSPSSN---EDALESDNNEKGKEGDSSGANDEAPDLDPEIEFVTFVTGDPENPHNWPAWIRWSYTVLLSILVICVAYGSACISGGLGTVEKKYHVGMEAAILSVSLMVIGFSLGPLIWSPVSDLYGRRVAYFVSMGLYVIFNIPCALAPNLGSLLACRFLCGVWSSSGLCLVGGSIADMFPSETRGKAIAFFAFAPYVGPVVGPLVNGFISVSTGRMDLIFWVNMAFAGVMWIISSAIPETYAPVILKRKAARLRKETGNPKIMTEQEAQG------VSMGEMMRACLLRPLYFSVTEPVLVATCFYVCLIYSLLYAFFFAFPVIFGELYGYKDNLVGLMFIPIVIGALWALATTFYCENKYLQIVKQRKPTPEDRLLGAKIGAPFAAIALWILGATAYKHIIWVGPASAGLAFGFGMVLIYYSLNNYIIDCYVQYASSALATKVFLRSAG-----GAAFPLFTIQMYHKLNLHWGSWLLAFISTAMIALPFAFSYWGK-------------GLRHKLSKKDYSIDSIE----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. . : : . .: .. : . : . . :* * *. .: :. .* : : * :*.:: . ::* :**: : * : :::.. . . * . : * . . * :: :: : . : : *: :: : . . . : : . .. : .:: . : : :: :: .: . ..: : *: *: :.. : : .. :: .* :* . : . : ::. * . :. : : . : : .* * . . . :. ", "identical_positions": 21, "similar_positions": 119, "identity": "3.22%" }, { "cls_id": "homologset.agr.SGD:S000006361", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IQ55-1", "uniprot_id": "Q8IQ55_DROME", "id": "Q8IQ55-1", "name": "Vacuolar protein sorting-associated protein 62", "aln": "MSKQLKTNSLSLLHCQAALLLLLFCVAALQAQQAQQMVQQQQQQLPAGVAATTAAATSPASSNMRLLNATSAGVAATFIDNTSSNASRNDHMVQNNENPASFEQQTLQLQQQQQQATVQYAHISPLDKEVVERLIKQWAPIVWLAPEEKFMPLGVEEFLQYVHPMDKDSSFRPGVPFREYSTKSHLVTNNEVQELLGNDKSFLYGRNPNEKAVPIYGVVNLCPSTRAPAMPVVPTTPPTTTRGVYIPVSIDPLEERNDTIRRSSRLFPLFQRVKRESPTVPQYNQLNEYEELVMEATQKPSVQQDSEPEPENGVPVNNFIANLADNVKFSGGTYPDDNLEENSIGQAPEKEEGPGKGKLPGFHVTYWMFYPYSQGKTMCTVSLGPLGRIPFPAVYGYCLGNRKDIGSHVGDWEHMSLYFNGDAEPQAMYVSAHDAGAYYSYNRLTGSFEFRRQETRKGILQRPNFPKTVTTFKNHPVLFAAKGSHGLWTAPGKHRFVKVARLYDINGFGTPWN--TWKAVDISYENLRSYGRSLVPDWLTYRGKWGNPKSNCHPFRRIGLNFCEFTDGPTGIPLKEPHFQCGADYR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06466-1", "uniprot_id": "TDA6_YEAST", "id": "Q06466-1", "name": "Putative vacuolar protein sorting-associated protein TDA6", "aln": "------------MHCVLARILLWFLIVDLSVIRALVLPPLKDYDP-----------------------------LEPLMKRDMAMGQRNRFKVDG------------QLPPILNSTDVTDDQRSLHTPGEIPSYVINHCPLVHLYSEEKYWPSDIAEYVQNFQIKDKNG---NSISTHENLTLHDLKAEYHVDLFGNKTETHIPSSE--------VFLTSLDDFDKDPKWLLGHLPEYGTGYNSKAPAILIVVDKGNGWVDAFWFFFYPFNHGPFIMGHGPWGNHVGDWEHSLVRFYK--------------GIPKYLWMS-----AHSSGTGYRYEAVEKFKKLRKRKQQDSDDGG---DTILERPLIFSARGTHANYASAGQHAHDIPFFFMPLSDFTDRGPLWDPS--LNFYSYTFDGKTVTPSSEREESLGLDWLHFQGGWGDQQLPARDPRQ--------KWCVAQWK-----YIGGPRGPLFKKLDRLNLCGGVKKWNFWNGGCPARRLIKKAEGLDSESTDLMGDNCGVLLYRIRPKWLRGILRFLMWRGILCSLMEFFTN------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** * :** * :. *.. :* : :: : .::.. : ..** . *:. ** :.: * : * : : : .*:* * .***: * .: *::* .: **:. .:. :* * .* :: .*: : .: ::.: . : :..* : * : . * . *. : ::: *. : :* *:: * *::.::*. ::. : *:* ::: .: ** * : :*: . : ::::. . * . : :::. :: : : *** : : :* : . :. * *:*.: . : . . : :: *. :: ::.*: *: :* : . *:. .: .: .: ::: . * * . ** .:. *. * . * ** . . :* * .: ** . ", "identical_positions": 72, "similar_positions": 165, "identity": "12.29%" }, { "cls_id": "homologset.agr.SGD:S000006364", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09811-1", "uniprot_id": "PYGL_RAT", "id": "P09811-1", "name": "Glycogen phosphorylase, liver form", "aln": "-------------------------MAKPLTDQEKRRQISIRGIVGVEN--------------VAELKKGFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQ-------------LGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIREGWQVEEADDWLRHGNPWEKARPEFMLPVHFYGRVEHTQAG------TKWVDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDFNLQDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDVIRRFKASKFGSKDGVGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWSKAWEITKKTFAYTNHTVLPEALERWPVDLVEKLLPRHLQIIYEINQKHLDRIVALFPKDIDRMRRMSLIEEEGGKR-INMAHLCIVGCHAVNGVAKIHSDIVKTQVFKDFSELE-PDKFQNKTNGITPRRWLLLCNPGLADLIAEKIG---EDYVKDLSQLTKLHSFVGDDIFLREIAKVKQENKLKFSQFLEKEYK-VKIN-----PSSMFDVHVKRIHEYKRQLLNCLHVITMYNRIK---------KDPKKFFVPRTVIIGGKAAPGYHMAKMIIKLVTSVAEVVNNDPMVGSKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVDDVAALDKKGYEAKEYYEALP-ELKLVIDQIDNGFFSPNQPDLFKDIINMLFYH-DRFKVFADYEAYVKCQEKVSQLYMNQK-AWNTMVLRNIAASGKFSSDRTIREYAKDIWNMEPSDLKISLSKESSNGVNANGK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ET01-1", "uniprot_id": "PYGL_MOUSE", "id": "Q9ET01-1", "name": "Glycogen phosphorylase, liver form", "aln": "-------------------------MAKPLTDQEKRRQISIRGIVGVEN--------------VAELKKGFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQ-------------LGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIREGWQVEEADDWLRHGNPWEKARPEFMLPVHFYGRVEHTQTG------TKWVDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDFNLQDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDVIRRFKASKFGSKDGMGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWAKAWEITKKTFAYTNHTVLPEALERWPVELVEKLLPRHLEIIYEINQKHLDRIVALFPKDISRMRRMSLIEEEGGKR-INMAHLCIVGCHAVNGVAKIHSDIVKTQVFKDFSELE-PDKFQNKTNGITPRRWLLLCNPGLADLIAEKIG---EDYVKDLSQLTKLHSFVSDDIFLREIAKVKQENKLKFSQFLEKEYK-VKIN-----PSSMFDVHVKRIHEYKRQLLNCLHVITMYNRIK---------KDPKKFFVPRTVIIGGKAAPGYHMAKMIIKLITSVAEVVNNDPMVGSKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVDDVAALDKKGYEAKEYYEALP-ELKLVIDQIDNGFFSPNQPDLFKDIINMLFYH-DRFKVFADYEAYVKCQEKVSQLYMNQK-AWNTMVLKNIAASGKFSSDRTIKEYAKDIWNMEPSDLKISLSNESSNGVSANGK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06737-1", "uniprot_id": "PYGL_HUMAN", "id": "P06737-1", "name": "Glycogen phosphorylase, liver form", "aln": "-------------------------MAKPLTDQEKRRQISIRGIVGVEN--------------VAELKKSFNRHLHFTLVKDRNVATTRDYYFALAHTVRDHLVGRWIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQ-------------LGLDIEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIRDGWQVEEADDWLRYGNPWEKSRPEFMLPVHFYGKVEHTNTG------TKWIDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDFNLRDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKASKFGSTRGAGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWSKAWELTQKTFAYTNHTVLPEALERWPVDLVEKLLPRHLEIIYEINQKHLDRIVALFPKDVDRLRRMSLIEEEGSKR-INMAHLCIVGSHAVNGVAKIHSDIVKTKVFKDFSELE-PDKFQNKTNGITPRRWLLLCNPGLAELIAEKIG---EDYVKDLSQLTKLHSFLGDDVFLRELAKVKQENKLKFSQFLETEYK-VKIN-----PSSMFDVQVKRIHEYKRQLLNCLHVITMYNRIK---------KDPKKLFVPRTVIIGGKAAPGYHMAKMIIKLITSVADVVNNDPMVGSKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRIDDVAALDKKGYEAKEYYEALP-ELKLVIDQIDNGFFSPKQPDLFKDIINMLFYH-DRFKVFADYEAYVKCQDKVSQLYMNPK-AWNTMVLKNIAASGKFSSDRTIKEYAQNIWNVEPSDLKISLSNES-NKVNGN-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58H0W7-1", "uniprot_id": "A0AC58H0W7_DANRE", "id": "A0AC58H0W7-1", "name": "Alpha-1,4 glucan phosphorylase", "aln": "---------------MFITIYGLIRMATPLTDQEKRKQISIRGIVGVEN--------------VAELKKGFNRHLHFTLVKDRNVATPRDYYFALSHTVRDHLVGRWIRTQQFCYEADPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQ-------------LGLDMEDLEEMEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIKDGWQVEEADDWLRYGNPWEKARPEFMLPVHFYGRVEEEEGKE-----PKWVDTQVVLAMPYDTPIPGYMNNTVNTMRLWSARAPNDFNLRDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDVIRRFKTSKRNTSGPLS--FDSFPDKVAIQLNDTHPAMAIPELMRIFVDIEKLDWDTAWDITKRTFAYTNHTVLPEALERWPVDLMEKLLPRHLQIIYKINLIHLNHIASLFPEDMDRIRRMSLIEEGGGKR-VNMAHLCIVGSHKVNGVAKIHSDIIKRDVFQDFSELE-PEKFQNKTNGITPRRWLLLCNPGLADLIAEAIG---EEYVKDLTQLQKLNDLVDDEAFIRDVAKVKQDNKLKFAHYLEKIYK-VDIN-----PASMFDVHVKRIHEYKRQLLNCLHVITMYNRIK---------SHPTKPFIPRTVIIGGKAAPGYHMAKMIIKLITSVADVVNNDPVIGRKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVNDVAELDKKGYNALQYYENLS-ELKRAINQIKSGYFSPKQPEMFSDIINMLFHH-DRFKVFADYESYVKCQDRVSALYKDQR-EWTRVVIKNIAASGKFSSDRTITEYATEIWGVEPTDLKIPPPGEPREALEETARSLRKT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8CI94-1", "uniprot_id": "PYGB_MOUSE", "id": "Q8CI94-1", "name": "Glycogen phosphorylase, brain form", "aln": "-------------------------MAKPLTDSERQKQISVRGIAGLGD--------------VAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQTACDEATYQ-------------LGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDG------VLWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLKDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSRFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKR-INMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELE-PEKFQNKTNGITPRRWLLLCNPGLAEIIVERIG---EGFLTDLSQLKKLLSLVDDEAFIRDVAKVKQENKLKFSAQLEKEYK-VKIN-----PASMFDVHVKRIHEYKRQLLNCLHIITLYNRIK---------KDPAKAFVPRTVMIGGKAAPGYHMAKMIIKLVTSIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVEDVEALDQKGYNAREFYERLP-ELRQAVDQISSGFFSPKDPDCFKDVVNMLMYH-DRFKVFADYEAYIQCQAQVDRLYRNSK-EWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPPNLPKD------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53534-1", "uniprot_id": "PYGB_RAT", "id": "P53534-1", "name": "Glycogen phosphorylase, brain form", "aln": "-------------------------MAKPLTDSERQKQISVRGIAGLGD--------------VAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQTACDEATYQ-------------LGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPNG------VLWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLKDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKR-INMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELE-PEKFQNKTNGITPRRWLLLCNPGLAEIIVERIG---EGFLTDLSQLKKLLSLVDDEAFIRDVAKVKQENKLKFSAQLEKEYK-VKIN-----PCSMFDVHVKRIHEYKRQLLNCLHIITLYNRIK---------KDPTKTFVPRTVMIGGKAAPGYHMAKMIIKLVTSIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVEDVEALDQKGYNAQEFYERLP-ELRQAVDQISSGFFSPKDPDCFKDVVNMLMYH-DRFKVFADYEAYIQCQAQVDHLYRNPK-DWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPP-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11216-1", "uniprot_id": "PYGB_HUMAN", "id": "P11216-1", "name": "Glycogen phosphorylase, brain form", "aln": "-------------------------MAKPLTDSEKRKQISVRGLAGLGD--------------VAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNACDEAIYQ-------------LGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDG------VKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKR-INMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELE-PEKFQNKTNGITPRRWLLLCNPGLADTIVEKIG---EEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQENKLKFSAFLEKEYK-VKIN-----PSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIK---------RDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVEALDRKGYNAREYYDHLP-ELKQAVDQISSGFFSPKEPDCFKDIVNMLMHH-DRFKVFADYEAYMQCQAQVDQLYRNPK-EWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPPNIPRD------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4IG19-1", "uniprot_id": "A4IG19_DANRE", "id": "A4IG19-1", "name": "Alpha-1,4 glucan phosphorylase", "aln": "-------------------------MSKPLTDHERRKQISVRGIAGLGD--------------VAEIKKSFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQYYYEKDPKRIHYLSLEFYMGRTLQNTMINLGLQNTCDEAIYQ-------------LGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMASLGLAAYGYGIRYEFGIFNQKIAHGWQIEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTHDG------PKWVDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFNLQEFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTSFETFHEKVAIQLNDTHPALAIPELMRILVDIEHLDWEKAWEITTKTCAYTNHTVLPEALERWPVYMFEKLLPRHLQIVYEINRRHLDRISALYPGDTDRLRRMSLIEEGDPKR-INMAHLCVVGSHAVNGVARIHSDIVKTTVFKDFCDIE-PEKFQNKTNGITPRRWLLLCNPGLADIIAEKIG---EDFLTDLFQLRKLLDFINDEMFIRDVAKVKQENKQKFAAYLENEYN-VKIN-----PESIFDIQVKRIHEYKRQLLNCLHIITLYNRIK---------KEPNKKFVPRTVMIGGKAAPGYHMAKMIIKLITSVGEVVNHDPVVGDRLKVIFLENYRVSLAEKVVPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVQDVEDMDKKGYNAREYYERLP-ELKLVMDQISTGFFSPKEPELFKDVVNMLMDH-DRFKVFADYESYISCQDKVNELYKNPK-EWTKKVIRNIAASGKFSSDRTIAEYAREIWGVEPSDVKIPPPNEPRE------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9WUB3-1", "uniprot_id": "PYGM_MOUSE", "id": "Q9WUB3-1", "name": "Glycogen phosphorylase, muscle form", "aln": "-------------------------MSRPLSDQDKRKQISVRGLAGVEN--------------VSELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQ-------------LGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQG------AKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGSRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRILVDLERLDWDKAWDVTVKTCAYTNHTVLPEALERWPVHLMETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKR-INMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELE-PHKFQNKTNGITPRRWLVLCNPGLAEVIAERIG---EDYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFSAYLEREYK-VHIN-----PNSLFDVQVKRIHEYKRQLLNCLHIITLYNRIK---------REPNRFMVPRTIMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPAVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVERLDQRGYNAQEYYDRIP-ELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHH-DRFKVFADYEEYIKCQDKVSELYKNPR-EWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAPDEKI-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09812-1", "uniprot_id": "PYGM_RAT", "id": "P09812-1", "name": "Glycogen phosphorylase, muscle form", "aln": "-------------------------MSRPLSDQDKRKQISVRGLAGVEN--------------VSDLKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVDRWIRTQQHYYAKDPKRIYYLSLELYMGRTLQNTMVNLALENACDEATYQ-------------LGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQG------AKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPPYFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDKFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELIRILVDLERLDWDKAWDVTVKTCAYTNHTVLPEALERWPVHLMETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKR-INMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELE-PHKFQNKTNGITPRRWLVLCNPGLAEVIAERIG---EEYISDLDQLRKLLSYLDDQAFIRDVAKVKQENKLKFSAYLETEYK-VHIN-----PNSLFDVQVKRIHEYKRQLLNCLHIITLYNRIK---------REPNRFMVPRTIMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPAVGDRFRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEDNFFIFGMRVEDVERLDQRGYNAQEYYDRIP-ELRQIIEQLSSGFFSPKQPDLFKDIVNMVMHH-DRFKVFADYEEYIKCQDKVSELYKNPR-EWTRMVIRNIATSGKFSSDRTIAQYAREIWGLEPSRQRLPAPDEKI-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11217-1", "uniprot_id": "PYGM_HUMAN", "id": "P11217-1", "name": "Glycogen phosphorylase, muscle form", "aln": "-------------------------MSRPLSDQEKRKQISVRGLAGVEN--------------VTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQ-------------LGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKISGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGHVEHTSQG------AKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRILVDLERMDWDKAWDVTVRTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKR-INMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELE-PHKFQNKTNGITPRRWLVLCNPGLAEVIAERIG---EDFISDLDQLRKLLSFVDDEAFIRDVAKVKQENKLKFAAYLEREYK-VHIN-----PNSLFDIQVKRIHEYKRQLLNCLHVITLYNRIK---------REPNKFFVPRTVMIGGKAAPGYHMAKMIIRLVTAIGDVVNHDPAVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDKLDQRGYNAQEYYDRIP-ELRQVIEQLSSGFFSPKQPDLFKDIVNMLMHH-DRFKVFADYEDYIKCQEKVSALYKNPR-EWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAPDEAI-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EXT3-1", "uniprot_id": "E7EXT3_DANRE", "id": "E7EXT3-1", "name": "Alpha-1,4 glucan phosphorylase", "aln": "-------------------------MSKPLTDQEKRKQISVRGLAGVEN--------------VADLKTNFNRHLHFTLVKDRNVATKRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRVYYLSLEFYMGRTLQNTMVNLALENACDEAIYQ-------------LGLDMEELQDIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVKGWQVEEADDWLRYGNPWEKARPEYMRPVHFYGRVEHHPDG------VKWVDTQVVLALPYDTPVPGYRNNIVNTMRLWSAKAPCEFHLKDFNVGGYIQAVLDKNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKASKFGSTEIVRMDLSTLPDKVAIQLNDTHPAMAIPELMRILVDDEKLTWDVAWDITVRTCAYTNHTVLPEALERWPVDLFQNLLPRHLEIIYEINRRHMERISALYPGDFDRLRRMSLIEEGGQKK-INMAHLCIVGSHAVNGVAQIHSDIIKDTVFKDFYDVD-PQKFQNKTNGITPRRWLVMCNPGLAEVIAERIG---EDYIRDLSQLKKLLKFVDDDALIRDIAKVKQENKMKFAVHLEEQYK-VKIN-----PNSMFDVHVKRIHEYKRQLLNCLHIITLYNRIK---------KEPNKAWTPRTIMIGGKAAPGYHTAKMIIKLITSIGDVVNNDIVVGDRLKVIFLENYRVTLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVKDVEAMDKKGYDAMEYYNRIP-ELKQAMDQISGGYFSPADPDQFKDIVNMLMHH-DRFKVFADYEDYIQCQDKVSALYKNTK-EWTKMVIHNIAGCGKFSSDRTISQYAREIWGMEPSLEKIAAPDDSR-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XTL9-1", "uniprot_id": "PYG_DROME", "id": "Q9XTL9-1", "name": "Glycogen phosphorylase", "aln": "-------------------------MSKPQSDADRRKQISVRGIAEVGN--------------VTEVKKNFNRHLHYTLVKDRNVSTLRDYYFALANTVKDNMVGRWIRTQQHYYEKDPKRVYYLSLEYYMGRSLTNTMINLGIQSECEEAMYQ-------------LGLDIENLEEMEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFAQKIKNGEQVEEPDDWLRYGNPWEKARPEFMLPVNFYGRVIDTPEG------KKWVDTQRVFAMPYDNPIPGYNNNHVNTLRLWSAKSPIDFNLKFFNDGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFMCAATLQDIIRRYKASKFGSREAVRNTFDHFPDKVAIQLNDTHPSLAIPELMRILVDEEHLTWEKAWDITVRSCAYTNHTVLPEALERWPVSLLESILPRHLQIIYHINFLHMENVKKKFPDDLDRMRRMSMVEEDGEKR-INMAHLSIVGSHAVNGVAAIHSQILKDSLFHDFYEME-PQKFQNKTNGITPRRWLLLCNPGLSDLIAEKIG---DEWPVHLDQLVALKKWAKDPNFQRNVARVKQENKLKLAAILEKDYG-VKIN-----PSSMFDIQVKRIHEYKRQLLNCLHIITLYNRIK---------KDPTANFTPRTIMIGGKAAPGYYVAKQIIKLICAVGNVVNNDPIVGDKLKVIFLENYRVTLAEKIMPAADLSEQISTAGTEASGTGNMKFQLNGALTIGTLDGANVEMAEEMGLDNIFIFGMTVDEVEALKKKGYNAYDYYNANP-EVKQVIDQIQGGFFSPGNPNEFKNIADILLKY-DHYYLLADYDAYIKAQDLVSKTYQNQA-KWLEMSINNIASSGKFSSDRTIAEYAREIWGVEPTWEKLPAPEDQPQN-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06738-1", "uniprot_id": "PHSG_YEAST", "id": "P06738-1", "name": "Glycogen phosphorylase", "aln": "MPPASTSTTNDMITEEPTSPHQIPRLTRRLTGFLPQEIKSIDTMIPLKSRALWNKHQVKKFNKAEDFQDRFIDHVETTLARSLYNCDDMAAYEAASMSIRDNLVIDWNKTQQKFTTRDPKRVYYLSLEFLMGRALDNALINMKIEDPEDPAASKGKPREMIKGALDDLGFKLEDVLDQEPDAGLGNGGLGRLAACFVDSMATEGIPAWGYGLRYEYGIFAQKIIDGYQVETPDYWLNSGNPWEIERNEVQIPVTFYGYVDRPEGGKTTLSASQWIGGERVLAVAYDFPVPGFKTSNVNNLRLWQARPTTEFDFAKFNNGDYKNSVAQQQRAESITAVLYPNDNFAQGKELRLKQQYFWCAASLHDILRRFKKSK--------RPWTEFPDQVAIQLNDTHPTLAIVELQRVLVDLEKLDWHEAWDIVTKTFAYTNHTVMQEALEKWPVGLFGHLLPRHLEIIYDINWFFLQDVAKKFPKDVDLLSRISIIEENSPERQIRMAFLAIVGSHKVNGVAELHSELIKTTIFKDFVKFYGPSKFVNVTNGITPRRWLKQANPSLAKLISETLNDPTEEYLLDMAKLTQLGKYVEDKEFLKKWNQVKLNNKIRLVDLIKKENDGVDIINREYLDDTLFDMQVKRIHEYKRQQLNVFGIIYRYLAMKNMLKNGASIEEVAKKYPRKVSIFGGKSAPGYYMAKLIIKLINCVADIVNNDESIEHLLKVVFVADYNVSKAEIIIPASDLSEHISTAGTEASGTSNMKFVMNGGLIIGTVDGANVEITREIGEDNVFLFGNLSENVEELR---YNHQYHPQDLPSSLDSVLSYIESGQFSPENPNEFKPLVDSIKYHGDYYLVSDDFESYLATHELVDQEFHNQRSEWLKKSVLSVANVGFFSSDRCIEEYSDTIWNVEPVT-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :. :. *: : : . . :.: * *:. **.:. . : * : :::*::* * :*** ***::***** ***:* *:::*: :: : * : **:.:*:: : * ****************:****: *:.*:***:***:*** *** * *:* .* **. ***** * * ** *** * *:. : *:*:.** *:**: .. **.:***.*:.. *.: ** *.* ::* ::: **.*: ******:* :********:** **:*:*::**:* *: : ::**********:::* ** *::** *:: * **::. :: *******: ****:*** :. :*****:*:* ** .:: : :* * . : *:*::** :: :.**.*.: *.* ***** :**:::* :*:** .. * ** * ********** .**.*:. * * :. : : .: :* * * : :. :** :** :: :: *.* ::**::********** ** : :: * :* . :. ::***:****: ** **:*: .:.::**:* : ::*:*: :*.*: ** ::**:***::***********.**** :**.* ***:******::.* * :*.*:** .:* : *: . : . .: :. :. * *** :*: *. : : : : * : : *:: *: : *. : : * : .:* * ***** * :*: **.:** ", "identical_positions": 326, "similar_positions": 241, "identity": "34.83%" }, { "cls_id": "homologset.agr.SGD:S000006365", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q641Z4-1", "uniprot_id": "CDK9_RAT", "id": "Q641Z4-1", "name": "Cyclin-dependent kinase 9", "aln": "-----------------------------------------MAKQYDSVECPFCDEVTKYEKLAKIGQGTFGEVFKAKHRQTGQK-VALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTK-----ASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFS--------LAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVWPNVDK-YELFEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPS---------DLKGMLSTHLTSMFEYLAP----------------------------PRRKGSQITQQSTNQSRNPATTNQTEFERVF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J95-1", "uniprot_id": "CDK9_MOUSE", "id": "Q99J95-1", "name": "Cyclin-dependent kinase 9", "aln": "-----------------------------------------MAKQYDSVECPFCDEVTKYEKLAKIGQGTFGEVFKAKHRQTGQK-VALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTK-----ASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFS--------LAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVWPNVDK-YELFEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPS---------DLKGMLSTHLTSMFEYLAP----------------------------PRRKGSQITQQSTNQSRNPATTNQTEFERVF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50750-1", "uniprot_id": "CDK9_HUMAN", "id": "P50750-1", "name": "Cyclin-dependent kinase 9", "aln": "-----------------------------------------MAKQYDSVECPFCDEVSKYEKLAKIGQGTFGEVFKARHRKTGQK-VALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTK-----ASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFS--------LAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVWPNVDN-YELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPS---------DLKGMLSTHLTSMFEYLAP----------------------------PRRKGSQITQQSTNQSRNPATTNQTEFERVF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXE8-1", "uniprot_id": "CDK9_DANRE", "id": "Q7SXE8-1", "name": "Cyclin-dependent kinase 9", "aln": "-----------------------------------------MSKYYDGVEFPFCDEFSKYEKLAKIGQGTFGEVFKAKHRQTGKK-VALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKG---EATQFNRYKGSIYLVFDFCEHDLAGLLSNANVKFTLAEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFS--------LAKNSQGNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLTLISQLCGSITPEVWPGVDKKYELYQKMELPKGQKRKVKDRLKAYVKDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPS---------DLKNMLSTHNTSMFEYLAP----------------------------PRRRG-HMPQQPANQNRNPATTSQSEFDRVF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O17432-1", "uniprot_id": "O17432_DROME", "id": "O17432-1", "name": "", "aln": "----------MAHMSHMLQQPSGSTPSNVGSSSSRTMSLMEKQKYIEDYDFPYCDESNKYEKVAKIGQGTFGEVFKAREKKGNKKFVAMKKVLMDNEKEGFPITALREIRILQLLKHENVVNLIEICRTK-----ATATNGYRSTFYLVFDFCEHDLAGLLSNMNVKFSLGEIKKVMQQLLNGLYYIHSNKILHRDMKAANVLITKHGILKLADFGLARAFS--------IPKNESKNRYTNRVVTLWYRPPELLLGDRNYGPPVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQLCGSFTPDVWPGVEE-LELYKSIELPKNQKRRVKERLRPYVKDQTGCDLLDKLLTLDPKKRIDADTALNHDFFWTDPMPS---------DLSKMLSQHLQSMFEYLAQ----------------------------PRRSNQMRNYHQQLTTMNQKPQDNSMIDRVW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23293-1", "uniprot_id": "BUR1_YEAST", "id": "P23293-1", "name": "Serine/threonine-protein kinase BUR1", "aln": "MSDNGSPAVLPKTEFNKYKIGKVKSTPAIQRDAKTNLTYIKLRKRSSEKVYGCTVFQNHYREDEKLGQGTFGEVYKGIHLETQRQ-VAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEEDWAVARY---LPGAELTTTNYKPTLRERFGKYLSET-GLDFLGQLLALDPYKRLTAMSAKHHPWFKEDPLPSEKITLPTEESHEADIKRYKEEMHQSLSQRVPTAPRGHIVEKGESPVVKNLGAIPRGPKKDDASFLPPSKNVLAKPPPSKIRELHQNPRPYHVNSGYAKTAIPPPAAPAGVNRYGPNNSSRNNRFSGNSTAPNNSRNPVNRFHPETNVSSKYNKVPLPLGPQSRYQGNSNESRYKNSPNDSRYHNPRYVNKPETNFNRQPQKYSRQESNAPINKNYNPSNGSRNMAGDHHQGSRPSHPQFPISPSQGQHQLTSKPIEKKNGSFKDERAKPDESKEFQNSDIADLY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .:*.: *:********:*. . : :: **:**:::. **: ***** *** **: *:*:*:::***: : : . : ::*::: : **:*:* * ::: : :**.:* :*:** *** *::***:*:**:** :.*:********** : . :**. *** ***.***:**:::* ..:*:**.**::**:: :.**:**:*: .* .* :* *: * : *. . * .. * :::*: *: : . *::.:**.*** :*: : * :* :* **:** . . :. : .*.: *: *:: . : . . :.: ", "identical_positions": 122, "similar_positions": 122, "identity": "18.43%" }, { "cls_id": "homologset.agr.SGD:S000006366", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P9Z8-1", "uniprot_id": "ORC4_RAT", "id": "Q6P9Z8-1", "name": "Origin recognition complex subunit 4", "aln": "--------MSNRKSKNN--IHAECLSQVQRILRER---------------FCHHTPHSNLFG------------VQVQYKHLIELLKRTAIYGESNSLLIVGPRGSGKTTLLNHALKELMQIGDMSENVLQVHLNGLLQTNDKIALKEITRQLN-----------------LENVVGDKVFGSFAENLSFLLEALQKGNRT---------SSCPVIFILDEFDLFAHQKNQTLLYNLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFD-FPQYLKIFKEQLSLPAE----------------------FPDKIFA-----------EKWNENAHCLSED--STVLEVLQKHFNVNKNLQSLHMLLMLALNRVTVTHPFMTSADLMEAQHLCSLDAKASIVHG----LSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFIQRKAHSVYNFEKPV----------------------VMKAFEHLQQLELIKPMERTSV-----------NSQREYQLVKLLLDNTQIMNALQKYSNCPTDVRQWATSSLSWL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88708-1", "uniprot_id": "ORC4_MOUSE", "id": "O88708-1", "name": "Origin recognition complex subunit 4", "aln": "--------MSSRKTKSN--AHAECLSQVQRILRER---------------FCHHSPHSNLFG------------VQVQYKHLIELLKRTAIYGESNSVLIVGPRGSGKTTLLNHALKELMEI-EVSENVIQVHLNGLLQTNEKIALKEITRQLN-----------------LDNVVEDKVFGSFAENLSFLLEALQKGDRT---------SSCPVIFILDEFDIFAHQKNQTLLYNLFDISQSAQTPVAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFD-FPQYLKIFKEQLSLPAE----------------------FPDKAFA-----------ERWNENVHCLSED--STVLEVLQKHFSVNKNLQSLHMLLMLALNRVTVSHPFMTSADLMEAQHMCSLDSKANIVHG----LSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFIQRKAHSVYNFEKPV----------------------VMKAFEHLQQLELIKPVERTSV-----------NSQREYQLVKLLLDNTQIMNALQKYSNCPTDVRQWATSSLSWL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43929-1", "uniprot_id": "ORC4_HUMAN", "id": "O43929-1", "name": "Origin recognition complex subunit 4", "aln": "--------MSSRKSKSNSLIHTECLSQVQRILRER---------------FCRQSPHSNLFG------------VQVQYKHLSELLKRTALHGESNSVLIIGPRGSGKTMLINHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLN-----------------LENVVGDKVFGSFAENLSFLLEALKKGDRT---------SSCPVIFILDEFDLFAHHKNQTLLYNLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFG-FPQYVKIFKEQLSLPAE----------------------FPDKVFA-----------EKWNENVQYLSED--RSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAVDLMEASQLCSMDSKANIVHG----LSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRKAHSVYNFEKPV----------------------VMKAFEHLQQLELIKPMERTSG-----------NSQREYQLMKLLLDNTQIMNALQKYPNCPTDVRQWATSSLSWL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QRE0-1", "uniprot_id": "F1QRE0_DANRE", "id": "F1QRE0-1", "name": "Origin recognition complex subunit 4", "aln": "--------MSKRRPAALS--DVQCVSLVQELLRER---------------LCHQKLPDQPIG------------LDSQYKHLLELLRRTAVHGESNSVLIVGPRGSGKTMLLGCVLRELMSLKEVQKNVLLVELNGLLQTDDKIALKEITRQLH-----------------LENVVGDKVFGSFAENLAFLLEALKKGDKS---------SSRPVLFLLDEFDLFAHHKNQTLLYNLLDVSQSAQTPVAVVGLTCRLDVLELLEKRVKSRFSHRQIHLFSSLS-FSQYVDVVRLQLSLPQD----------------------FPDHRFS-----------SQWNQSVTKLCED--KSVLEVLKRSFNSSKDFRSLYSLLFMAVSRVSVSHSTLCEADFLESGRLISADSKANVLHG----LSILELCLIIAMKHLNDTYDGEPFNFQMVHNEFKKFIQRKSHSIHKFEKPV----------------------VMKAFEHLLQLELVRPVDSGVC-----------KVQREYQLMRLMLEHGQVMEALQRYPQCPTDVKQWALSAFA--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W102-1", "uniprot_id": "Q9W102_DROME", "id": "Q9W102-1", "name": "Origin recognition complex subunit 4", "aln": "--------MPEAD---------RELVSIRRFLKER---------------LQRD--YTTLRG------------YAKERSNVRLLLQRTAEMGESNSLLLLGPRGSGKTTLINSVLADLLPNKSFGENTLIVHLDGNLHTDDRVALKSITVQMQ-----------------LENAADGKVFGSFAENLAFLLQCLKAGGKH---------SKS-VIFILEEFDLFCAHHNQTLLYNLFDVSQSAQAPICVLGVTCRLDVIELLEKRVKSRFSHRQVFLFPSLRRFEDYVDLCRDLLSLPTGNSLLLAAEKIYNLQNIQSGALYFSRNHFDPGEYGFSPRLRDAWNKQICKVLAT--QQARSTLQALHDFDISEAYLKNFLFRLVAHLRPQSPHITAEKMAAVGSQFEGDDKIELLCG----LSVLELCLIIAIKHHSQIYDRDSFNFEIIYARFSKFAK-VSTTMQAVERSI----------------------VLKAFEHLRIAELIMPLTGGAGGG-------VGKVQKEFEMHKLALTYSQIHHCMQRYQALPTEVAQWAQSSLI--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54791-1", "uniprot_id": "ORC4_YEAST", "id": "P54791-1", "name": "Origin recognition complex subunit 4", "aln": "MTISEARLSPQVNLLPIKRHSNEEVEETAAILKKRTIDNEKCKDSDPGFGSLQRRLLQQLYGTLPTDEKIIFTYLQDCQQEIDRIIKQSIIQKESHSVILVGPRQSYKTYLLDYELSLLQQS--YKEQFITIRLNGFIHS-EQTAINGIATQLEQQLQKIHGSEEKIDDTSLETISSGSLTEVFEKILLLLDSTTKTRNEDSGEVDRESITKITVVFIFDEIDTFAGPVRQTLLYNLFDMVEHSRVPVCIFGCTTKLNILEYLEKRVKSRFSQRVIYMPQIQN-LDDMVDAVRNLLTVRSE-----------------------ISPWVS------------QWNETLEKELSDPRSNLNRHIRMNFETFRSLPTLKNSIIPLVATSKNFGSLCTAIKSCSFLDIYNKNQLSNNLTGRLQSLSDLELAILISAARVALRAKDGSFNFNLAYAEYEKMIKAINSRIPTVAPTTNVGTGQSTFSIDNTIKLWLKKDVKNVWENLVQLDFFTEKSAVGLRDNATAAFYASNYQFQGTMIPFDLRSYQMQIILQELRRIIPKSNMYYSWTQL--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . : :*::* : * ..: ::::: **:*::::*** * ** *:. * * :: : :.*:* :: :: *:: *: *:. *:. ..: * : * :* . : .. :. *:*:::*:* *. .*******:*: : ::.*:.:.* * :*:::* **********:* :.: : : :. : *:: . **: :: .. . * :: : . . . : . : * ** **:.::*: : . .***:: : .:.*: : : . . * :.:*:* ::. : * : : : * *: :*. .. : : ", "identical_positions": 74, "similar_positions": 136, "identity": "12.98%" }, { "cls_id": "homologset.agr.SGD:S000006367", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI72-1", "uniprot_id": "IF4H_RAT", "id": "Q5XI72-1", "name": "Eukaryotic translation initiation factor 4H", "aln": "---------------------------------------------------------MADFDTYDDRAYSSFGGGR---GSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIFKD-----LSIRSVRLVRD-KDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAE-----GRK---QDKGGFGFRKGGPDDRGMGGSREP----------------------RGGWDS---RDDFSSGYRD------DFLGGRG-----GSRPGDR-------RAGPPMGSRFRDGPPLRGSNMDFREPTEEER----------------------AQRPRLQLKPRTVATP------------LNQVANPN-----SAIFGGARPR---------EEVVQKEQE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUK2-1", "uniprot_id": "IF4H_MOUSE", "id": "Q9WUK2-1", "name": "Eukaryotic translation initiation factor 4H", "aln": "---------------------------------------------------------MADFDTYDDRAYSSFGGGR---GSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIFKD-----LSIRSVRLVRD-KDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAE-----GRK---QDKGGFGFRKGGPDDRGMGGSRES----------------------RGGWDS---RDDFNSGYRD------DFLGGRG-----GSRPGDR-------RAGPPMGSRFRDGPPLRGSNMDFREPTEEER----------------------AQRPRLQLKPRTVATP------------LNQVANPN-----SAIFGGARPR---------EEVVQKEQE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8BGD9-1", "uniprot_id": "IF4B_MOUSE", "id": "Q8BGD9-1", "name": "Eukaryotic translation initiation factor 4B", "aln": "-MAASAKKKNKKGKTISLTD-----FLAEDGGTGGGSTYVPKPVSWADETDDLEGDVSTTWHSNDDDVYRAPPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEDSIKDFFRG-----LNISAVRLPREPSNPDRLKGFGYAEFEDLDSLLSALSLNEESLGNRRIRVDVAD-----QAQDKDRDDRSFGRDRNRDSDKTDTDWRARPTTDSFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPRLNLKPRSAPKE------------DDASASTSQSSRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLDRRPRERHPSWRSEETQERERSRTGSESSQTGASATSGRNTRRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSSDTEQPSPTSGGGKVAAVQPPEEGPSRKDGNKVDVVGATQGQAGSCSRGPGDGGSRDHWKDLDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALSVDGEDEDEGDDCTE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23588-1", "uniprot_id": "IF4B_HUMAN", "id": "P23588-1", "name": "Eukaryotic translation initiation factor 4B", "aln": "-MAASAKKKNKKGKTISLTD-----FLAEDGGTGGGSTYVSKPVSWADETDDLEGDVSTTWHSNDDDVYRAPPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFFRG-----LNISAVRLPREPSNPERLKGFGYAEFEDLDSLLSALSLNEESLGNRRIRVDVAD-----QAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKE------------DDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALSVDGEDENEGEDYAE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7PLL3-1", "uniprot_id": "Q7PLL3_DROME", "id": "Q7PLL3-1", "name": "", "aln": "MASAGKKGKKNKGTVISLQS-----FLCNSDAPVGTTQVSKK---------------IRNLDGDDSDDGSGTLPLVYQLPTAPRANR--IFDDNSIPHKAPFIAYINNLPFDANEDDLYEFFEG-----INLISLRLPREDGENGRSRGFGYVELENREDLIHVLSLPDPSIKGRRIRIELSNE---NDQQSRQKSNRRFDGFGNNGDNRDSGNWRRD-------------------------SQNNGSNFGYSSNFERSFNRERKSLPDRDDVNTPGSWRTSARPQS--IDTSPTRREVEQVSEKYREGRVKIADRYSREE-----------------TSKVEEERPKLNLKPRTLPLPDVKTIEFEKCDVDEFNLDKQGGTSSLNVFGSAKPVDTAARELEIEQRLALARKQ-----DKGRREQGLNEKLAELQVDKNDNESLSATVSWRTNQDYKESDKINKCPGEKQRDEEIHRLN--------------------------------------------------------------------------------------------HARGQFNRPELLREKPNANGESKRDCRNDRSVSKKTSQNDLVLQSSNKYSGLDNEGSE---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34167-1", "uniprot_id": "IF4B_YEAST", "id": "P34167-1", "name": "Eukaryotic translation initiation factor 4B", "aln": "-MAPPKKTVKKMDLTSFLNDDTFGSSWAEEDVDLNKITIPIETANANTIPLSELAHAKNNSNNTRSGGFGGSFGGRSRLDPALGGGSSDRREEYPVPDAPPYRAVINNIPWDITPEGVQAWVEDGLVKPEAVEEVVLPKNLRDPTRLKGNAFVTLKERADLVAVLKFNGTKLNERTVYVSVAAPRRGGGADVDWSSARGSNFQGDGREDAPDLDWGAAR------------------------------GSNFRGPRREREEVDIDWTAARGSNFQGSSRPPRRE------REEVDIDWSAARGSNFQGSSRPPRREREEPD-----------------IDWSAARGSNFQSSSRPPRRE------------REEPDIDWSAARGSNFQSSSRPP-----------RREREKEEPALDWGAAR-----GAQFGKPQQTKNTYKDRSLTNKKTTDEQPKIQKSVYDVLRTEDDDED-------------------------------------------------------------------------------------------------------------EEAEKQNGDAKENKVDAAVEKLQDKTAQLTVEDGDNWEVVGKK------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . . :* .*: * :.*:*:: .: ... : : * :: : : :* :. :.: .* .*. : * : :.:: . . . . .: . .: . . . *. .* . : . .. . ..:: ..*. : . ..::* :: ", "identical_positions": 14, "similar_positions": 75, "identity": "2.19%" }, { "cls_id": "homologset.agr.SGD:S000006369", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NUX8-1", "uniprot_id": "RHOAA_DANRE", "id": "Q6NUX8-1", "name": "Rho-related GTP-binding protein RhoA-A", "aln": "----------------------------------------------------------------------MA---AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELQKMKQEPVKPEEGRDMANRINAFGYLECSAKTKEG-VREVFEMATRAALQAK-----KRGKK---------------------------NACALL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7T2E8-1", "uniprot_id": "RHOAC_DANRE", "id": "Q7T2E8-1", "name": "Rho-related GTP-binding protein RhoA-C", "aln": "----------------------------------------------------------------------MA---AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRINAFGYLECSAKTKDG-VREVFEMATRAALQAR-----KRGKK---------------------------SGCLLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9QUI0-1", "uniprot_id": "RHOA_MOUSE", "id": "Q9QUI0-1", "name": "Transforming protein RhoA", "aln": "----------------------------------------------------------------------MA---AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDG-VREVFEMATRAALQAR-----RGKKK---------------------------SGCLIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61589-1", "uniprot_id": "RHOA_RAT", "id": "P61589-1", "name": "Transforming protein RhoA", "aln": "----------------------------------------------------------------------MA---AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDG-VREVFEMATRAALQAR-----RGKKK---------------------------SGCLIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61586-1", "uniprot_id": "RHOA_HUMAN", "id": "P61586-1", "name": "Transforming protein RhoA", "aln": "----------------------------------------------------------------------MA---AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDG-VREVFEMATRAALQAR-----RGKKK---------------------------SGCLVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DHM9-1", "uniprot_id": "RHOAB_DANRE", "id": "Q6DHM9-1", "name": "Rho-related GTP-binding protein RhoA-B", "aln": "----------------------------------------------------------------------MA---AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELTKMKQEPVKAEEGRDMANRIGAFGYMECSAKTKDG-VREVFEMATRAALQAR-----RGKKS---------------------------NKCCLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q62159-1", "uniprot_id": "RHOC_MOUSE", "id": "Q62159-1", "name": "Rho-related GTP-binding protein RhoC", "aln": "----------------------------------------------------------------------MA---AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEG-VREVFEMATRAGLQVR-----KNKRR---------------------------RGCPIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABZ3NNM4-1", "uniprot_id": "A0ABZ3NNM4_RAT", "id": "A0ABZ3NNM4-1", "name": "", "aln": "MLRAAPVDPPPLDGPAPERCWRVGRGSGQSQPPAPAAQLEAAEQKLGQEHTWISLSDSTQKLQFRAGISVMA---TIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEG-VREVFEMATRAGLQVR-----KNKRR---------------------------RGCPIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08134-1", "uniprot_id": "RHOC_HUMAN", "id": "P08134-1", "name": "Rho-related GTP-binding protein RhoC", "aln": "----------------------------------------------------------------------MA---AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEG-VREVFEMATRAGLQVR-----KNKRR---------------------------RGCPIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DHE8-1", "uniprot_id": "RHOAD_DANRE", "id": "Q6DHE8-1", "name": "Rho-related GTP-binding protein RhoA-D", "aln": "----------------------------------------------------------------------MA---AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELIKMKQEPVKPEEGRDMANRISAFGYLECSAKTKDG-VREVFEMATRAALQVR-----KRKKR---------------------------SGCLLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P62746-1", "uniprot_id": "RHOB_MOUSE", "id": "P62746-1", "name": "Rho-related GTP-binding protein RhoB", "aln": "----------------------------------------------------------------------MA---AIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEG-VREVFETATRAALQKR-----YGSQNGC------------------------INCCKVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62745-1", "uniprot_id": "RHOB_HUMAN", "id": "P62745-1", "name": "Rho-related GTP-binding protein RhoB", "aln": "----------------------------------------------------------------------MA---AIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEG-VREVFETATRAALQKR-----YGSQNGC------------------------INCCKVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62747-1", "uniprot_id": "RHOB_RAT", "id": "P62747-1", "name": "Rho-related GTP-binding protein RhoB", "aln": "----------------------------------------------------------------------MA---AIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEG-VREVFETATRAALQKR-----YGSQNGC------------------------INCCKVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48148-1", "uniprot_id": "RHO1_DROME", "id": "P48148-1", "name": "Ras-like GTP-binding protein Rho1", "aln": "----------------------------------------------------------------------MT---TIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDPNTIRDLAKMKQEPVKPQEGRAMAEKINAFAYLECSAKSKEG-VRDVFETATRAALQVK-----KRKKT----------------------------RCLLL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06780-1", "uniprot_id": "RHO1_YEAST", "id": "P06780-1", "name": "GTP-binding protein RHO1", "aln": "-----------------------------------------------------------------MSQQVGN---SIRRKLVIVGDGACGKTCLLIVFSKGQFPEVYVPTVFENYVADVEVDGRRVELALWDTAGQEDYDRLRPLSYPDSNVVLICFSIDLPDSLENVQEKWIAEVLHFCQGVPIILVGCKVDLRNDPQTIEQLRQEGQQPVTSQEGQSVADQIGATGYYECSAKTGYG-VREVFEAATRASLMGKSKTNGKAKKNTTEK---------------------KKKKCVLL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P97348-1", "uniprot_id": "RHOD_MOUSE", "id": "P97348-1", "name": "Rho-related GTP-binding protein RhoD", "aln": "----------------------------------------------------------MNASQVAGEEAPQS---GHSVKVVLVGDGGCGKTSLMMVFAKGAFPESYSPTVFERYNATLQMKGKPVHLQIWDTAGQDDYDRLRPLFYPDANVLLLCFDVTNPNSFDNVSNRWYPEVTHFCKGVPIIVVGCKIDLRKDKVLVNNLRKKRLEPVTYHRGHDMARSVGAVAYLECSARLHDN-VEAVFQEAAEVALSSRRHNFWRRITQ---------------------------NCCLAT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6SA80-1", "uniprot_id": "RND3_RAT", "id": "Q6SA80-1", "name": "Rho-related GTP-binding protein RhoE", "aln": "-------------------------------------------------------MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKSCTVM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61588-1", "uniprot_id": "RND3_MOUSE", "id": "P61588-1", "name": "Rho-related GTP-binding protein RhoE", "aln": "-------------------------------------------------------MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKSCTVM", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*:***. ****.*: **:*. *** * *****.* * .::. : :.* :***:*. **.:*** ***::.:*:**.: *::::.: ::* *: .** .. :::*. * *** * :* . ** . * :* : * * **** . *. :*. *: . : * ", "identical_positions": 66, "similar_positions": 55, "identity": "22.07%" }, { "cls_id": "homologset.agr.SGD:S000006370", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60783-1", "uniprot_id": "RT14_HUMAN", "id": "O60783-1", "name": "Small ribosomal subunit protein uS14m", "aln": "MAAFMLGSLLRTFKQMVPSSASG--QVRSHYVDWRMWRDVKRRKMAYEYADERLRINSLRKNTILPKILQDVADEEIAALPRDSCPVRIRNRCVMTSRPRGVKRRWRLSRIVFRHLADHGQLSGIQRATW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CR88-1", "uniprot_id": "RT14_MOUSE", "id": "Q9CR88-1", "name": "Small ribosomal subunit protein uS14m", "aln": "MAASVLGSLLRTFRQAVPPSASG--QVRGYYVDWRMLRDLKRRKMAYEYADERLRINSLRKNTILPKDLQEMAGDEIAALPRDSCPVRIRNRCVMTSRPRGVKRRWRLSRIVFRHLADHGLLSGVQRAIW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LGB8-1", "uniprot_id": "A0ABK0LGB8_RAT", "id": "A0ABK0LGB8-1", "name": "28S ribosomal protein S14, mitochondrial", "aln": "--MAIEGLVFKCGSEAVPLSSSG--QARGYYVDWRMLRDVKRRKMAYEYADERLRINSLRKNTILPKDLQEMAGDEIAALPRDSCPVRIRNRCVMTSRPRGVKRRWRLSRIVFRHLADHGLLSGVQRAIW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VWI3-1", "uniprot_id": "Q9VWI3_DROME", "id": "Q9VWI3-1", "name": "28S ribosomal protein S14, mitochondrial", "aln": "--MNSLARIGGFVCQSVQIAGCGLQQVRTKYADWKMIRDVKRRKCVKENAVERLRVNSLRKNDILPPELREVADAEIAAFPRDSSLVRVRERCALTSRPRGVVHKYRLSRIVWRHLADYNKLSGVQRAMW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10663-1", "uniprot_id": "RT02_YEAST", "id": "P10663-1", "name": "Small ribosomal subunit protein uS14m", "aln": "-----MGNFRFPIKTKLPPG----------FINARILRDNFKRQQFKENEILVKSLKFIARNMNLPTKLRLEAQLKLNALPNYMRSTQIKNRCVDSGHARFVLSDFRLCRYQFRENALKGNLPGVKKGIW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . : : :: ** :*: * :: : :* ** *: * :: *:*. .::::**. :.:.* * :**.* :*. * . *.*:::. *", "identical_positions": 23, "similar_positions": 39, "identity": "17.69%" }, { "cls_id": "homologset.agr.SGD:S000006372", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7K6-1", "uniprot_id": "D4A7K6_RAT", "id": "D4A7K6-1", "name": "Mediator of RNA polymerase II transcription subunit 10", "aln": "----------MAEKFDHLEEHLEKFVENIRQLGIIVSDFQ--PSSQAGLSQKLNFIVTGLQDIDKCR----QQLHDITVPLEVF-EYIDQGRNPQLYTKECLERALAKNEQVKGKIDTMKKFKSLLIQELSKVFPEDMAKYRSIRGEDHPPS------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CXU0-1", "uniprot_id": "MED10_MOUSE", "id": "Q9CXU0-1", "name": "Mediator of RNA polymerase II transcription subunit 10", "aln": "----------MAEKFDHLEEHLEKFVENIRQLGIIVSDFQ--PSSQAGLSQKLNFIVTGLQDIDKCR----QQLHDITVPLEVF-EYIDQGRNPQLYTKECLERALAKNEQVKGKIDTMKKFKSLLIQELSKVFPEDMAKYRSIRGEDHPPS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BTT4-1", "uniprot_id": "MED10_HUMAN", "id": "Q9BTT4-1", "name": "Mediator of RNA polymerase II transcription subunit 10", "aln": "----------MAEKFDHLEEHLEKFVENIRQLGIIVSDFQ--PSSQAGLNQKLNFIVTGLQDIDKCR----QQLHDITVPLEVF-EYIDQGRNPQLYTKECLERALAKNEQVKGKIDTMKKFKSLLIQELSKVFPEDMAKYRSIRGEDHPPS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0VIA1-1", "uniprot_id": "MED10_DANRE", "id": "Q0VIA1-1", "name": "Mediator of RNA polymerase II transcription subunit 10", "aln": "----------MAEKFDNLEEHLEKFVENIRQLGIIVSDFQ--PSSQTGLNQKLNFMITGLQDIEKCR----QQLHDINVPLEVF-EYIDQGRNPQLYTKECLERALAKNEQVKGKIDTLTKFKSLLISELGKVFPEEMAKYKAIHGDD-PPS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9GYU7-1", "uniprot_id": "MED10_DROME", "id": "Q9GYU7-1", "name": "Mediator of RNA polymerase II transcription subunit 10", "aln": "----------MSAPLENLETQLEMFIENVRQIRIIVSDFQ--PQGQNVLNQKINSLVTGLQEIDKLR----SQVQDVYVPFEVFFDYIDQDKNPQLYTKDCVEKALAKNEEVKGKIEGLKKFKTNLLLELYKTFPNEMNNYRAYRKDSM---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06213-1", "uniprot_id": "MED10_YEAST", "id": "Q06213-1", "name": "Mediator of RNA polymerase II transcription subunit 10", "aln": "MNGNSTNNEQLQQELATTQDQVASIIESFVELGVSIYDFPGTPEATKGMITNLQRNVDRLYKLNVRSNDPQSSLSKVDIPLEVV-QYIEDGRNPDIYTREFVEAIRRSNQYQRGKMHGLKQLRDSLADKIVDEFPELKEPVEDIIKRTSPIDNVSNTH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :: ::*.. :: : : ** *.. : ::: : * .:: ..: .: :*:**. :**::.:**::**:: :* .*: :**:. :.::: * :: . **: . ", "identical_positions": 21, "similar_positions": 56, "identity": "13.29%" }, { "cls_id": "homologset.agr.SGD:S000006373", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CX97-1", "uniprot_id": "WDR55_MOUSE", "id": "Q9CX97-1", "name": "WD repeat-containing protein 55", "aln": "---------------------------------------------------------------------------------------------------------------------MDPTCEESPAEDSNNEEEDLDSTKAAPRIRDTPEDIVLEAPASGLAFHPTRDLLAAGDVDGDVFVFAYSCQEGE-TKELWSSGHHLKSCRAVVFSEDGQKLVTVSKDKAIHILDVEQGQLERRI---------SKAHSAPINSVLLVDENALVTGDDTGGIRLWD---QRKEGPLMDMRQHEEYIADMALDPAKKLLLTASGDGCLGVFNIKRR-----------RFELLSEPQSGDLTSVALMK--YGKKVACGSSEGTIYLFN--WNGFGATSDRFALR-AESIDCIVPVT--ENLLCTGSTDGIIRAVNILPNRVVGTVGQHAGEPVEALALSHCGHFLASSGHDQRLKFWDMTQLRTV--VVDDYRRRKKKGGPLRALSSKAWST-DDFFAGLRED-EEDAKAPEEVVRESDDDDDDSD----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1L112-1", "uniprot_id": "WDR55_RAT", "id": "A1L112-1", "name": "WD repeat-containing protein 55", "aln": "---------------------------------------------------------------------------------------------------------------------MDPTCQESPAEDSNNEE-DLDSTKAAPRIRDTPEDIVLEAPASGLAFHPTRDLLAAGDVDGDVFVFAYSCQEGE-TKELWSSGHHLKSCRAVVFSEDGQKLVTVSKDKAIHVLDVEQGQLERRI---------SKAHSAPINSLLLVDENVLVTGDDTGGIRLWD---QRKEGPLMDMRQHEEYIADMALDPAKKLLLTASGDGCLGVFNIKRR-----------RFELLSEPQSGDLTSVALMK--YGKKVACGSSEGTIYLFN--WNGFGATSDRFALR-AESIDCMVPVT--ENLLCTGSTDGIIRAVNILPNRVVGTVGQHAGEPVEELALSHCGHFLASSGHDQRLKFWDMTQLRTV--VVDDYRRRKKKGGPLRALSSKAWST-DDFFAGLRED-EEEAKAPEEVSGESDDDSD-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H6Y2-1", "uniprot_id": "WDR55_HUMAN", "id": "Q9H6Y2-1", "name": "WD repeat-containing protein 55", "aln": "---------------------------------------------------------------------------------------------------------------------MDRTCEERPAEDGSDEE-DPDSMEAPTRIRDTPEDIVLEAPASGLAFHPARDLLAAGDVDGDVFVFSYSCQEGE-TKELWSSGHHLKACRAVAFSEDGQKLITVSKDKAIHVLDVEQGQLERRV---------SKAHGAPINSLLLVDENVLATGDDTGGICLWD---QRKEGPLMDMRQHEEYIADMALDPAKKLLLTASGDGCLGIFNIKRR-----------RFELLSEPQSGDLTSVTLMK--WGKKVACGSSEGTIYLFN--WNGFGATSDRFALR-AESIDCMVPVT--ESLLCTGSTDGVIRAVNILPNRVVGSVGQHTGEPVEELALSHCGRFLASSGHDQRLKFWDMAQLRAV--VVDDYRRRKKKGGPLRALSSKTWST-DDFFAGLREE-GEDSMAQEEKE-ETGDDSD-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DRF9-1", "uniprot_id": "WDR55_DANRE", "id": "Q6DRF9-1", "name": "WD repeat-containing protein 55", "aln": "---------------------------------------------------------------------------------------------------------------------MATPTEH---EDLSEQEVTEDEFKTP-KIRETPEDIKLEAIVNTIAFHPKQDILAAGDIDGDIYLFSYSCTEGE-NKELWSSGHHLKSCRKVLFSSDGQKLFSVSKDKAIHIMDVEAGKLETRI---------PKAHKVPINAMLLIDENIFATGDDEGTLKVWD---MRKGTSFMDLKHHEDYISDITIDQAKRTLLTSSGDGTLGVFNIKRR-----------RFELLSEIQNGDLTSVSIMK--RGRKVVCGSGEGTIYIFN--WNGFGATSDRFAVQ-AESVDCIVPIT--DSILCAASTDGVIRAINILPNRVVGSIGQHVGEAIEEIARCRDTHFLASCAHDELIKFWDISSLPDE--KVNDYRRRKKKDRRLKALSNKAFDTGQNFFAGLLDTTEENGKEGENDEDDDDEDSDSGSD---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8T088-1", "uniprot_id": "WDR55_DROME", "id": "Q8T088-1", "name": "WD repeat-containing protein 55 homolog", "aln": "MHTHNNFKTPSDEDELDDLDEDMVVGVIAEIEQEVLNESDSDNDEYDLVDMGAPVPDNDGDISYEGNDSSSSDDSFDPNAADSDSDDSMLDEAGGVTAGGATSAKKRKDDDNPSGSNKQPEATFDLDEDDETDETVRAMIAAIKKPRSSPPEIKLEDFITDICFHPDRDIIALATIIGDVHLYEYDNEAN---KLLRTIEVHSKACRDVEFTEDGRFLLTCSKDKCVMVTDMETEKLKKLY---------ETAHDDAINTLHVLNENLFASGDDAGTVKLWD---LRTKNAIFELKELEDQITQLTTNEQSKLLLATSADGYLTTFNISAR-----------KMYVQSEPYEEELNCMGVYR--GDSKLVVGTSKGRLYTYN--WGQFGYHCDMYPGI-KSPISLMIPIT--DRIACVAGEDGNIRACHIAPYRNLGVVGQHN-MPIESLDVNASGELIASSSHNNDVRFWNVKYFEDFG-DIKYNEKHNAYKEQRHNLPSSKCSNASDFFSDLTKENADGDDDPGAGPSNMA-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06214-1", "uniprot_id": "JIP5_YEAST", "id": "Q06214-1", "name": "WD repeat-containing protein JIP5", "aln": "--------------------------------------------------------------------------MAKSKKKTDVVDSTNLPILELLSLKAPIFQSLLHPELPIIITGFGTGHIVCHRYDPAKLQSHLDRRRRIDTATTGKDAKKGVCPWIRLDIDLETGDLKFVDIEEQQQQKQTGKDEDLGVKTLWKTKRHKGSVRAMCFDSKGDNIFSVGSDNVLKKANTMTGKVVKKVNLSSLFNSEEKKNDKFTKLCASQTHPFILIGDESGNIHVINSENLALSNSIRSIHFGDSINDIFHFDKRSAYKFISLGQTTLAYFDVRDKDAKPNVAGNEDGKILISDDQEDEVLCGCFVDPEVADTLLCGMGEGIVTVWKPNKNDLEDQMSRIKISKDESIDCIVPTLQDDNCVWCGCSNGNIYKVNAKLGKVVEIRNHSELDEVSFVDLDFEYRVVSGG--LENIKIWELSSDDVEENASVESDSDEPLSHSDEDLSDDTSSDDETTLVGLSKEELLDELDKDLKEDHQEEKESNSKSVKKRKIMKENNKKKDLYEHGIKKFDDL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : :. . : : : . . * * . * : * : * ..* :.: ..*: : : :: . : : . : **: * : : : .: .:: :. : : . : : .: * *:: : : *: . :: . . .: * .:* : :: . : . ..:. ::* : . :* * : : : .: :. : ..::. : :::*:: : . *... . . : .* . . ", "identical_positions": 22, "similar_positions": 107, "identity": "3.87%" }, { "cls_id": "homologset.agr.SGD:S000006377", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q793F9-1", "uniprot_id": "VPS4A_RAT", "id": "Q793F9-1", "name": "Vacuolar protein sorting-associated protein 4A", "aln": "------------------------------------------------------------------------------------------------------------------------------MTTSTLQKAIDLVTKATEEDKAKNYEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRAKCMQYLDRAEKLKDYLRNKEKHGKK--PVKENQS---EGKGSDSDSEG--DNPEKKKLQEQLMGAVVMEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRRRFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELARKTEGYSGADISIIVRDSLMQPVRKVQSATHFKKVCGPSRTNPSVMIDDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVCMSDMLRSLATTRPTVNADDLLKVKKFSEDFGQES-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEJ9-1", "uniprot_id": "VPS4A_MOUSE", "id": "Q8VEJ9-1", "name": "Vacuolar protein sorting-associated protein 4A", "aln": "------------------------------------------------------------------------------------------------------------------------------MTTSTLQKAIDLVTKATEEDKAKNYEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRAKCMQYLDRAEKLKDYLRNKEKHGKK--PVKENQS---EGKGSDSDSEG--DNPEKKKLQEQLMGAVVMEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRRRFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELARKTEGYSGADISIIVRDSLMQPVRKVQSATHFKKVCGPSRTNPSVMIDDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVCMSDMLRSLATTRPTVNADDLLKVKKFSEDFGQES-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UN37-1", "uniprot_id": "VPS4A_HUMAN", "id": "Q9UN37-1", "name": "Vacuolar protein sorting-associated protein 4A", "aln": "------------------------------------------------------------------------------------------------------------------------------MTTSTLQKAIDLVTKATEEDKAKNYEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRAKCVQYLDRAEKLKDYLRSKEKHGKK--PVKENQS---EGKGSDSDSEG--DNPEKKKLQEQLMGAVVMEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRRRFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELARKTEGYSGADISIIVRDSLMQPVRKVQSATHFKKVCGPSRTNPSMMIDDLLTPCSPGDPGAMEMTWMDVPGDKLLEPVVCMSDMLRSLATTRPTVNADDLLKVKKFSEDFGQES-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AP98-1", "uniprot_id": "A0A8M3AP98_DANRE", "id": "A0A8M3AP98-1", "name": "vesicle-fusing ATPase", "aln": "------------------------------------------------------------------------------------------------------------------------------MTTSTLQKAIELVTKATEEDKAKNYEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRGKCMQYLDRAEKLKDYLKNKDKQGKK--PVKETQS---NDK-SDSDSEG--ENPEKKKLQEHLMGAIVMEKPNVRWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFDLARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDGILVLGATNIPWVLDAAIRRRFEKRIYIPLPEEPARSAMFRLHLGNTPHSLTEADLRQLARKTDGYSGADISIIVRDALMQPVRKVQSATHFKKVRGPSRSNSAVIVDDLLTPCSPGDPEAIEMTWMDVPGDKLLEPIVCMSDMLRSLATTRPTVNTEDLLKVKKFTEDFGQEG-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P46467-1", "uniprot_id": "VPS4B_MOUSE", "id": "P46467-1", "name": "Vacuolar protein sorting-associated protein 4B", "aln": "----------------------------------------------------------------------------------------------------------------------------MASTNTNLQKAIDLASKAAQEDKAGNYEEALQLYQHAVQYFLHVVKYEAQGDKAKQSIRAKCTEYLDRAEKLKEYLKKKEKKPQK--PVKEEQSGPVDEKGNDSDGEAESDDPEKKKLQNQLQGAIVIERPNVKWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARENKPSIIFIDEIDSLCGSRSENESEAARRIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRRRFEKRIYIPLPEAHARAAMFRLHLGSTQNSLTEADFQELGRKTDGYSGADISIIVRDALMQPVRKVQSATHFKKVRGPSRADPNCIVNDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVSMWDMLRSLSSTKPTVNEQDLLKLKKFTEDFGQEG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7EZ84-1", "uniprot_id": "F7EZ84_RAT", "id": "F7EZ84-1", "name": "vesicle-fusing ATPase", "aln": "----------------------------------------------------------------------------------------------------------------------------MASTNTNLQKAIDLASKAAQEDKAGNYEEALQLYQHAVQYFLHVVKYEAQGDKAKQSIRAKCTEYLDRAEKLKEYLKKKEKKPQK--PMKEEQSGPVDEKGNDSDGEAESDDPEKKKLQNQLQGAIVIERPNVKWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARENKPSIIFIDEIDSLCGSRSENESEAARRIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRRRFEKRIYIPLPEAHARAAMFRLHLGSTQNSLTEADFQELGRKTDGYSGADISIIVRDALMQPVRKVQSATHFKKVRGPSRADPNCIVNDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVSMWDMLRSLSSTKPTVNEQDLLKLKKFTEDFGQEG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75351-1", "uniprot_id": "VPS4B_HUMAN", "id": "O75351-1", "name": "Vacuolar protein sorting-associated protein 4B", "aln": "----------------------------------------------------------------------------------------------------------------------------MSSTSPNLQKAIDLASKAAQEDKAGNYEEALQLYQHAVQYFLHVVKYEAQGDKAKQSIRAKCTEYLDRAEKLKEYLKNKEKKAQK--PVKEGQPSPADEKGNDSDGEGESDDPEKKKLQNQLQGAIVIERPNVKWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARENKPSIIFIDEIDSLCGSRSENESEAARRIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRRRFEKRIYIPLPEPHARAAMFKLHLGTTQNSLTEADFRELGRKTDGYSGADISIIVRDALMQPVRKVQSATHFKKVRGPSRADPNHLVDDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVSMSDMLRSLSNTKPTVNEHDLLKLKKFTEDFGQEG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GK36-1", "uniprot_id": "A0AC58GK36_DANRE", "id": "A0AC58GK36-1", "name": "vesicle-fusing ATPase", "aln": "MYNPHSRSVGGGNAPIFVGLPNRHKTPEEEEEEVRVDACKTQVPLLRQLIHVFQKAIAIAQKASEEDQAGHFEEAIKSYHHAVKYFLHIIKREPQGKEGNQKIREKCKQYLDRVEELQDYLDKKEATSCCYESKAIDLANKASQEDKAENYEEALRLYQHAVQYFLHVVKYEAQGDKAKQSIRAKCAEYLDRAEKLKEYLKKKEKAPAK--PVKESQS---NDKGNESDGE---EDPEKKKFQNQLSGAIVMEKPNIKWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSISSSDLVSKWLGESEKLVKSLFTLAREHKPSIIFIDEIDSLCGSRSENESEAARRIKTEFLVQMQGVGNDNEGILVLGATNIPWTLDSAIRRRFEKRIYIPLPEEHARSFMFKLNLGTTPNSLTESDFMTLGKKTDGYSGADISIIVRDALMQPVRKVQSATHFKQVRGPSRSDPNVIVDDLLTPCSPGDPQAKEMTWMEVPGEKLLEPIVSMSDMLRSLSNTKPTVNEQDLEKLKKFTEDFGQEG-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y162-1", "uniprot_id": "Q9Y162_DROME", "id": "Q9Y162-1", "name": "vesicle-fusing ATPase", "aln": "-----------------------------------------------------------------------------------------------------------------------------MAAGTTLQKAIDLVTKATEEDRNKNYAEALRLYEHGVEYFLHTIKYEAQGEKAKDSIRAKCLQYLDRAEKLKEYLKKGKKKPIK--EGGESSAKDDKDKKSDSDDED-GDDPEKKKLQSKLEDAIVIEKPKVQWSDVAGLDAAKEALKEAVILPIKFPQLFTGKRIPWKGILLFGPPGTGKSYLAKAVATEANRSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEIDSMCSARSDNENDSVRRIKTEFLVQMQGVGNDTDGILVLGATNIPWVLDSAIRRRFEKRIYIPLPEAHARLVMFKIHLGNTTHVLTEQDLKELAGKTEGYSGADISIVVRDALMEPVRKVQTATHFKRVSGPSPTNHEEIVNDLLVPCSPGDQGAVEMNWMDVPSDKLFEPPVTMRDMLKSLSRTKPTVNEDDLKKLRKFTEDFGQEG-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52917-1", "uniprot_id": "VPS4_YEAST", "id": "P52917-1", "name": "Vacuolar protein sorting-associated protein 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------MSTGDFLTKGIELVQKAIDLDTATQYEEAYTAYYNGLDYLMLALKYEKN-PKSKDLIRAKFTEYLNRAEQLKKHLESEEANAAKKSPSAGSGSNGGNKKISQEEGED-NGGEDNKKLRGALSSAILSEKPNVKWEDVAGLEGAKEALKEAVILPVKFPHLFKGNRKPTSGILLYGPPGTGKSYLAKAVATEAN-STFFSVSSSDLVSKWMGESEKLVKQLFAMARENKPSIIFIDEVDALTGTRGEGESEASRRIKTELLVQMNGVGNDSQGVLVLGATNIPWQLDSAIRRRFERRIYIPLPDLAARTTMFEINVGDTPCVLTKEDYRTLGAMTEGYSGSDIAVVVKDALMQPIRKIQSATHFKDVSTEDDETR------KLTPCSPGDDGAIEMSWTDIEADELKEPDLTIKDFLKAIKSTRPTVNEDDLLKQEQFTRDFGQEGN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.*:*. ** : * :* ** * :.::*:: .:*** : *:*: **.* :**:***:**.:*.. . * . . * .:.:.* . ::**:: * .*:: *:*:::*.*****:.************:***:**.*:* * ****:******************* *****:*****:***:********.** :**::*********:*:: .:*.:.*.:: ******:****:*** :.:* ********** **:*******:*******: ** **.:::* * **. : *. *:****:**:::*:*:**:*:**:*:***** * . *.****** * **.* :: .::* ** : : *:*::: *:**** .** * .:*:.*****. ", "identical_positions": 222, "similar_positions": 118, "identity": "38.88%" }, { "cls_id": "homologset.agr.SGD:S000006379", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ABZ5-1", "uniprot_id": "D4ABZ5_RAT", "id": "D4ABZ5-1", "name": "DNA polymerase epsilon subunit", "aln": "-----------MAPERLRSRTVSAFK-LRGLLLRSEATKYLTEALQS------------------VTELELEENLEKIIDAVEKQPLSSNMIERSVVEAAVQECSQSVDETI------------------------------------------------------EHIFNIIGAFDIPHFIYNSERKKFLPLSMTNH----AAPTIFGTARDKAELYRERYTILHQRTHRHELFTPPVIGS---------------HPDESGSKFQLKTIETLLGSTSKVGDVIVLGMITQLKEGKFFLEDPTGTVQLDLSKAQFHSG-LYTEACFVLAEGCFEDQ--VFHANAFGFPPTEPSSTTRAYYGNINFFGGP--------SNASVKASAKLRQLEEENKDAMFVIV-SDVWLDQVQVLEKLHVMFSGYSPAPPTCFILCGNFSSAPYGKNQVQ-------ALKDSLKSLADIICEYPSIHQSSRFVFVPGPE-------DPGFGSILPRPPLAESITQEFRQRVPFSVFTTNPCRIQYCTQEIIIFREDLVNKMCRNCVRFPSS----------------------------------SLDIPTHFVKTVLSQGHLAPLPLYVSPVYWAYDYTLRVYPVPDLLVIADKYDP-FTVTNTECLCINPGSFPRSG-FAFKVFYPSSKTVEDSKLQGF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54956-1", "uniprot_id": "DPOE2_MOUSE", "id": "O54956-1", "name": "DNA polymerase epsilon subunit 2", "aln": "-----------MAPERLRSRTVSAFK-LRGLLLRSEATKYLTEALQS------------------VTELELEENLGKIIDAVEKQPLSSNMIERSVVEAAVQECSQSMDETI------------------------------------------------------EHVFNIIGAFDIPRFIYNSERKKFLPLSMTNH----AAPTLFGTARDKAELYLERYTILHQRTHRHELFTPPVIGS---------------HLEESGSKFQLKTIETLLGSTSKVGDVIVLGMITQLKEGKFFLEDPTGTVQLDLSKAQFHSG-LYTEACFVLAEGWFEDQ--VFHANAFGFPPTEPSSTTRAYYGNINFFGGP--------SNASVKTYTKLRQLEDENKDAMFVIV-SDVWLDQVQVLEKFHVMFSGYSPAPPTCFILCGNFSSAPYGKNQVQ-------ALKDSLKSLADIICEYPSIHQSSRFVFVPGPE-------DPGFGSILPRPPLAESITQEFRQRVPFSVFTTNPCRIQYCTQEIIIFREDLVNKMCRNCVRFPSS----------------------------------SLDIPTHFVKTILSQGHLAPLPLYVCPVHWAYDYTLRVYPVPDLLVIADKYDP-FTVTNTDCLCINPGSFPRSG-FAFKVFYPSSKTVEDSKLQGF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56282-1", "uniprot_id": "DPOE2_HUMAN", "id": "P56282-1", "name": "DNA polymerase epsilon subunit 2", "aln": "-----------MAPERLRSRALSAFK-LRGLLLRGEAIKYLTEALQS------------------ISELELEDKLEKIINAVEKQPLSSNMIERSVVEAAVQECSQSVDETI------------------------------------------------------EHVFNIIGAFDIPRFVYNSERKKFLPLLMTNH----PAPNLFGTPRDKAEMFRERYTILHQRTHRHELFTPPVIGS---------------HPDESGSKFQLKTIETLLGSTTKIGDAIVLGMITQLKEGKFFLEDPTGTVQLDLSKAQFHSG-LYTEACFVLAEGWFEDQ--VFHVNAFGFPPTEPSSTTRAYYGNINFFGGP--------SNTSVKTSAKLKQLEEENKDAMFVFL-SDVWLDQVEVLEKLRIMFAGYSPAPPTCFILCGNFSSAPYGKNQVQ-------ALKDSLKTLADIICEYPDIHQSSRFVFVPGPE-------DPGFGSILPRPPLAESITNEFRQRVPFSVFTTNPCRIQYCTQEITVFREDLVNKMCRNCVRFPSS----------------------------------NLAIPNHFVKTILSQGHLTPLPLYVCPVYWAYDYALRVYPVPDLLVIADKYDP-FTTTNTECLCINPGSFPRSG-FSFKVFYPSNKTVEDSKLQGF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRQ7-1", "uniprot_id": "DPOE2_DROME", "id": "Q9VRQ7-1", "name": "DNA polymerase epsilon subunit 2", "aln": "---------MDVDLLPLRKRITNTFK-LCGFLIRSENSSYLAEQLLP------------------FDAAERDKWLTVITENLQSQKLLTPHVERAALEKAINELNRVGLDEG------------------------------------------------------ETVFALIDAFTVPRFRYNQRIKKFELDTQP--------RQLLTAPRMKSDYMQQRYAMLLQKTLRHDLFAPAVIQDGV-------------GAEAQAKKFKLQFAENLL-ATSAMKEAVVLGLLTQLKEGKFYVEDPTGCVQLDLTGARFHAG-FFCEGCFVLAEGNYNNG--VLKVDGLGFPPAEPANSSRAFFGTANTWGGE--------SAKLLKYSAGLQELERTNTETTIVFL-SDVRLDLPVVMEKLRQLFVGYDSCPPQAIVLMGPFTAS---TRNHH-------ELRHHLDALGGLAAGCEQLKKQTDLILVPSSE-------DPTAPNILPRAPIPECLAAGLLKAWPRTQLATNPCRLQYCTQQIVVCRLDLMAKFCRNTLHFPED----------------------------------TSQIEQHFARTIVCQGHLVPIHPIAMPVHWDYDPALWLYPLPDLIVMGDSCQS-FSSSQHGCTVLNTGSFVKSK-FAFKVYIPATRTIEDSEIPDELE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24482-1", "uniprot_id": "DPB2_YEAST", "id": "P24482-1", "name": "DNA polymerase epsilon subunit B", "aln": "MFGSGNVLPVKIQPPLLRPLAYRVLSRKYGLSIKSDGLSALAEFVGTNIGANWRQGPATIKFLEQFAAVWKQQERGLFIDQSGVKEVIQEMKEREKVEWSHEHPIQHEENILGRTDDDENNSDDEMPIAADSSLQNVSLSSPMRQPTERDEYKQPFKPESSKALDWRDYFKVINASQQQRFSYNPHKMQFIFVPNKKQNGLGGIAGFLPDIEDKVQMFLTRYYLTNDRVMRNENFQNSDMFNPLSSMVSLQNELSNTNRQQQSSSMSITPIKNLLGRDAQN--FLLLGLLNKNFKGNWSLEDPSGSVEIDISQTIPTQGHYYVPGCMVLVEGIYYSVGNKFHVTSMTLPPGERREITLETIGNLDLLGIHGISNNNFIARLDKDLKIRLHLLEKELTDHKFVILGANLFLDDLKIMTALSKILQKLNDDPPTLLIWQGSFTSVPVFASMSSRNISSSTQFKNNFDALATLLSRFDNLTENTTMIFIPGPNDLWGSMVSLGASGTLPQDPIPSAFTKKINKVCKNVVWSSNPTRIAYLSQEIVIFRDDLSGRFKRHRLEFPFNESEDVYTENDNMMSKDTDIVPIDELVKEPDQLPQKVQETRKLVKTILDQGHLSPFLDSLRPISWDLDHTLTLCPIPSTMVLCDTTSAQFDLTYNGCKVINPGSFIHNRRARYMEYVPSSKKTIQEEIYI---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** .:. *: ::.: . *:* : . . :. : : : : ** :* : :. : : . * :*.* :* ** . :* :: . * : ** : ::. *:: * . : . : ....:.: :.** : ::**::.: :*:: :***:* *::*:: : * : .*:**.** : . ::. .: :** * . : *. : * : . *: ** .: :*:: ::: ** :: : :: . ** :: * *:: ::. :.:*. : . .: :.: ::::*..: . . **: *:...:: : : ::** *: * :*:* : * ** :: *: :.** . . ::.:*:: **** *: *: * * :* : *:*. :*: *. .. * : * :*.*** :. : : *:.:. :.:: ", "identical_positions": 90, "similar_positions": 186, "identity": "12.97%" }, { "cls_id": "homologset.agr.SGD:S000006380", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08603-1", "uniprot_id": "PGTB2_RAT", "id": "Q08603-1", "name": "Geranylgeranyl transferase type-2 subunit beta", "aln": "--------MGTQQKDVTIKSDAP---DTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGVYWGLTVMDLMGQLHRMNKEEILVFIKSCQH-ECGGVSASIGHDPHLLYTLSAVQILTLYDSIHVINVD---KVVAYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLD-AINVEKAIEFVLSCMN-FDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSD---LLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFCMPEEVLQRVNVQPELVS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53612-1", "uniprot_id": "PGTB2_MOUSE", "id": "P53612-1", "name": "Geranylgeranyl transferase type-2 subunit beta", "aln": "MGSLLFSWKGTQQKDVTIKSDAP---DTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGVYWGLTVMDLMGQLHRMNREEILVFIKSCQH-ECGGISASIGHDPHLLYTLSAVQILTLYDSVHVINVD---KVVAYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLD-AINVEKAIEFVLSCMN-FDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSD---LLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFCMPEEVLQRVNVQPELVS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53611-1", "uniprot_id": "PGTB2_HUMAN", "id": "P53611-1", "name": "Geranylgeranyl transferase type-2 subunit beta", "aln": "--------MGTPQKDVIIKSDAP---DTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGIYWGLTVMDLMGQLHRMNREEILAFIKSCQH-ECGGISASIGHDPHLLYTLSAVQILTLYDSINVIDVN---KVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLD-AINVEKAIEFVLSCMN-FDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSD---LLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVNPVFCMPEEVLQRVNVQPELVS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9XZ68-1", "uniprot_id": "Q9XZ68_DROME", "id": "Q9XZ68-1", "name": "Geranylgeranyl transferase type-2 subunit beta", "aln": "MDFTTFVKPSNGGGDSGGGGDADGGGQKLQFWKHVEYIENHGKQEDDYEYCMTEFLRMSGIYWGTTALDIMGQLERLERKSIIEFVKRCQCPNTGGFAPCEGHDPHLLYTLSAIQILCTYDALEEIDRE---AVVRFVVGLQQPDGSFFGDKWGEVDTRFSFCAVASLTLLGRMEQTIDVEKAVKFVLSCCNQTDGGFGSKPGAESHAGLIYCCVGFFSLTHRLHLLDVD---KLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLTIMGRLHWISSEKLQQFILSCQDTETGGFSDRTGNMPDIFHTLFGIGGLSLLGHSGLKAINPTLCMPQYIIDRLGIKPQLLPRP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20133-1", "uniprot_id": "PGTB2_YEAST", "id": "P20133-1", "name": "Geranylgeranyl transferase type-2 subunit beta", "aln": "-----------------MSGSLT-----LLKEKHIRYIESLDTKKHNFEYWLTEHLRLNGIYWGLTALCVLDSPETFVKEEVISFVLSCWDDKYGAFAPFPRHDAHLLTTLSAVQILATYDALDVLGKDRKVRLISFIRGNQLEDGSFQGDRFGEVDTRFVYTALSALSILGELT-SEVVDPAVDFVLKCYN-FDGGFGLCPNAESHAAQAFTCLGALAIANKLDMLSDDQLEEIGWWLCERQLPEGGLNGRPSKLPDVCYSWWVLSSLAIIGRLDWINYEKLTEFILKCQDEKKGGISDRPENEVDVFHTVFGVAGLSLMGYDNLVPIDPIYCMPKSVTSKFKKYPYK----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. * ** ** . ..::.::** ::*.**:.*:*** *.: ::.. . : ::.:: *: * : *..:. **.*** ****:*** **::. :. : :: :: . * **** ** :**:**** : *:::*::**.: : *: *:.***.* * ***** *.:****. : * * :::: :*. :. * :**********.*******.************:** *:***.**. *** .*** *** :.**::**. : * ***:**:.****:* . : .:.* ***: : .:. * ", "identical_positions": 136, "similar_positions": 103, "identity": "38.53%" }, { "cls_id": "homologset.agr.SGD:S000006382", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7J8-1", "uniprot_id": "D4A7J8_RAT", "id": "D4A7J8-1", "name": "U4/U6 small nuclear ribonucleoprotein Prp4", "aln": "------------------------------MASSRASST-TTKTKAPDDLVAPVVKKPHIYYGSLEEKERERLAKGESGILGKEGLKAGIEAGNINITSGEVFEIEEHISERQAEVLAEFERRKRARQINVSTDDSEVKACLRALGEPITLFGEGPAERRERLRNILSVVGTDALKKTKKDDEKSKKS-KEEYQQTWYHEGPNSLKVARLWIANYSLPRAMKRLEEARLHKEIPETTRTSQMQELHKS-LRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSG-LCKLWSVPDCSLLHTLRGHNTNVGAIVFHPKSTVSLDQKDVNLASCAADGSVKLWSLDSDEPVADIEGHT----VRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGISFSPNGYHIATGSGDNTCKVWDLRQRR--CVYTIPAHQNLVTGVKFEPIHG-DFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAW6-1", "uniprot_id": "PRP4_MOUSE", "id": "Q9DAW6-1", "name": "U4/U6 small nuclear ribonucleoprotein Prp4", "aln": "------------------------------MASSRASST-TTKTKAPDDLVAPVVKKPHIYYGSLEEKERERLAKGESGILGKEGLKAGIEAGNINITSGEVFEIEEHISERQAEVLAEFERRKRARQINVSTDDSEVKACLRALGEPITLFGEGPAERRERLRNILSVVGTDALKKTKKDDEKSKKS-KEEYQQTWYHEGPNSLKVARLWIANYSLPRAMKRLEEARLHKEIPETTRTSQMQELHKS-LRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSG-LCKLWSVPDCSLLHTLRGHNTNVGAIVFHPKSTVSLDQKDVNLASCAADGSVKLWSLDSDEPVADIEGHT----VRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRR--CVYTIPAHQNLVTGVKFEPIHG-DFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43172-1", "uniprot_id": "PRP4_HUMAN", "id": "O43172-1", "name": "U4/U6 small nuclear ribonucleoprotein Prp4", "aln": "------------------------------MASSRASSTQATKTKAPDDLVAPVVKKPHIYYGSLEEKERERLAKGESGILGKDGLKAGIEAGNINITSGEVFEIEEHISERQAEVLAEFERRKRARQINVSTDDSEVKACLRALGEPITLFGEGPAERRERLRNILSVVGTDALKKTKKDDEKSKKS-KEEYQQTWYHEGPNSLKVARLWIANYSLPRAMKRLEEARLHKEIPETTRTSQMQELHKS-LRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSG-LCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHT----VRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRR--CVYTIPAHQNLVTGVKFEPIHG-NFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VVI0-1", "uniprot_id": "Q9VVI0_DROME", "id": "Q9VVI0-1", "name": "", "aln": "MSDDDDIQYIKRQRTLHYGSLEESERKRQNAAASGAAATTTSGTTASSGAGTTTTGTGGQLEDIDSDEDYEESTKKTSNAK-QAGAPPPTAATLANKIDDDYFDLEMEMERDKVALLEEFERKKRARQINVSTDDTEIKSNLRQLNEPICYFGEGPAERRRRLKELLAGLGENAINKRQYEDEERKQQQREQDQATWYHEGPDSLRIARLWLADYSLPRAKDRLVRAREALEVPSAARAGRMVEMQKK-LQSLAPLCSQVGDTRPVSSAAFSEDSSLLLTSSWSG-LCKLWSVPDCELKQTLRGHASYVGGVALRPG-VKADEENVVAMASGGHDGAVKLWGFNNEESIADITGHMP---HRVSKVAFHPSGRFLATACYDSSWRLWDLEQKTEVLHQEGHAKPVHCLSYHSDGSVLVTGGLDAFGRVWDLRTGRCIMFLEGHLGAVFGVDFSPNGFHIATGSQDNTCKIWDLRRRQ--PVYTIPAHTNLISDVKYQQECG-SFLVTCSYDSTTKIWSNKTWQPLKTLQGHDNKVISVDIAPNSQYIATTSFDRTFKLWSPDS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20053-1", "uniprot_id": "PRP4_YEAST", "id": "P20053-1", "name": "U4/U6 small nuclear ribonucleoprotein PRP4", "aln": "----------------------------------------------------------------------------MSKYIALENLPVDLQHKGATQNESTADILKQLPHERLQAVLEKIPE-----------EDLEVRRLLSILKKPEVVENEDVQQRRIRLAEILMVDEIDLENINNMEN-INGEEVDEEDDEDFFTPATSELIFARRFLINYSLERSRKRLQKEMERHQKFNTRQELLSRRTELQRMANLELAGSQLVSTKPISAVSLSTDDMVVATGSWAGDLQVLNSQTLQPLTQKLDSHVGKIGAIDWHPD-------SNNQMISCAEDGLIKNFQYSNEEGGLRLLGDLVGHERRISDVKYHPSGKFIGSASHDMTWRLWDASTHQELLLQEGHDKGVFSLSFQCDGSLVCSGGMDSLSMLWDIRSGSKVMTLAGHSKPIYTVAWSPNGYQVATGGGDGIINVWDIRKRDEGQLNQILAHRNIVTQVRFSKEDGGKKLVSCGYDNLINVYSSDTWLKMGSLAGHTDKIISLDISNNSHFLVSGGWDRSIKLWN---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . .. :: . :* :: . :* *:: * * :* .*. :** ** ::* : : : :: :. *: : :: ....* .** :: :*** *: .** . : .: : . . . : .* **: . :*:* :* :. :: *..*:* * * * . * :.* .* :*.: :* . : * . ** :* : ..:* : *. *:: * :****:*:.::.:* :***** . : *:* **** *. :::: ***: :**:*::. :**:*:* :* * ** :: : :****:::***. *. ::**:*:* : * ** *::: *::. * . *:: .**. :::: * : :* ** .*::.:**: :.: :.: .:**::*** ", "identical_positions": 113, "similar_positions": 157, "identity": "20.07%" }, { "cls_id": "homologset.agr.SGD:S000006384", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1T2-1", "uniprot_id": "SAE1_MOUSE", "id": "Q9R1T2-1", "name": "SUMO-activating enzyme subunit 1", "aln": "MVEKEEAGGGGGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLIVGMKGLGAEIAKNLILAGVKGLTMLDHEQVSPEDPGAQFLIQTGSVGRNRAEASLERAQNLNPMVDVKVDTEDVEKKPESFFTKFDAVCLTCCSRDVIIKVDQICHRNSIKFFTGDVFGYHGYTFANLG----EHEFVEEKTKVAKVSQGVEDGPEAKRAKLDSSETTMVKKKVLFCPVKEALEVDWSGEKAKAALKRTAPDYFLLQVLLKFRTDKGRDPTSESYKEDAELLLQIRNDVFDSLGISPDLLPDDFVRYCFS----EMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGSGIVECLGPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AXQ0-1", "uniprot_id": "SAE1_RAT", "id": "Q6AXQ0-1", "name": "SUMO-activating enzyme subunit 1", "aln": "MVEKEEVSGGGGG-ISEEEAAQYDRQIRLWGLEAQKRLRASRVLIVGMKGLGAEIAKNLILAGVKGLTMLDHEQVSPEDLGAQFLIRTGSVGQNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTEFDAVCLTCCSKDVIIKVDQICHRNSIKFFTGDVFGYHGYTFANLG----EHEFVEEKTKVTKVSQGVEDGPDAKRAKLDSSETTMVKKKVLFCPVKEALAVDWSGEKAQAALKRTAPDYFLLQVLLKFRTDKGRDPTSDSYSEDAELLLQIRNDVFDSLGVSPDLLPDDFVRYCFS----EMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGSGIVECLGPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBE0-1", "uniprot_id": "SAE1_HUMAN", "id": "Q9UBE0-1", "name": "SUMO-activating enzyme subunit 1", "aln": "MVEKEEAGGG----ISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLG----EHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDYFLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFS----EMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IQS6-1", "uniprot_id": "SAE1_DANRE", "id": "Q6IQS6-1", "name": "SUMO-activating enzyme subunit 1", "aln": "MIDTIEKEDT---IISEEEAAQYDRQIRLWGLDAQKRLRGSRVLLVGLRGLGAEVAKNLILAGVKGLTLLDHEQVTEESRRAQFLIPVDADGQNHAQASLERAQFLNPMVEVKADTEPVESKPDDFFFQFDAVCLTRCSRDLMVRVDQLCASRNIKVFCGDVYGYNGYMFSDLGQ---EYHYVEEKPKVVKGSNEANDGPEAKKPKIDPNETTMVKKTISFCSLKEALEVDWTTEKAKSSLKRIPADYFLLQVLLKFRTDKGRDPQPDSFAEDSQLLLQIRDDVLETMGLSSDLLPNTFVSYCFS----EMSPVCAVVGGVLGQEIVKALSQRDAPHRNFFFFDGLKGSGVVDYFSSK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KSM5-1", "uniprot_id": "Q7KSM5_DROME", "id": "Q7KSM5-1", "name": "SUMO-activating enzyme subunit 1", "aln": "MVVDMDTSET-AVELTEAENELYDRQIRLWGLESQKRLRTAKILIAGLCGLGAEITKNIILSGVNSVKLLDDKDVTEEDFCSQFLVPRESLNTNRAEASLTRARALNPMVDISADREPLKEKTSEFFGQFDVVVVNGATNEELLRIDTICRDLGVKFIATDVWGTFGFYFASLQ----KHSYVEDVIKHKVVAN-------SEKKKKYETVSIPTQRDVDYPGYSAWLDFDVTEPSYLRKLKRNGPGVLLLSVLQKFRTTHKRDPSYKTREADLELLRGIRDELLPNS-----ILGDEALGLIFA----QISPAVAVVGGVVAQEVIKVVTKLEAPHRNLFVFDPETCAGYVEAIGAK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06624-1", "uniprot_id": "RHC31_YEAST", "id": "Q06624-1", "name": "DNA damage tolerance protein RHC31", "aln": "MDMKVE-------KLSEDEIALYDRQIRLWGMTAQANMRSAKVLLINLGAIGSEITKSIVLSGIGHLTILDGHMVTEEDLGSQFFIGSEDVGQWKIDATKERIQDLNPRIELNFDKQDLQEKDEEFFQQFDLVVATEMQIDEAIKINTLTRKLNIPLYVAGSNGLFAYVFIDLIEFISEDEKLQSVRPTTVGPISSNRSIIEVTTRKDEEDEKKTYERIKTKNCYRPLNEVLSTATLKEKMTQRQLKRVTSILPLTLSLLQYG-LNQKGKAISFEQMKRDAAVWCENLGVPATVVKDDYIQQFIKQKGIEFAPVAAIIGGAVAQDVINILGKRLSPLNNFIVFDGITLDMPLFEF---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : ::* * *********: :* .:* :::*: .: .:*:*::*.::*:*: :.:** . *: *. :**:: . : :*: * : *** :::. * : ::.* ..** :** * . : :::: : .: . . * .: * .* : ::. . : . . : * : . :.: . : .: : . . : : . :: : : : :::*. *::** :.*:::: : : .* .*::.** . : : ", "identical_positions": 51, "similar_positions": 113, "identity": "14.25%" }, { "cls_id": "homologset.agr.SGD:S000006385", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DFC3-1", "uniprot_id": "B5DFC3_RAT", "id": "B5DFC3-1", "name": "Protein transport protein SEC23", "aln": "------MTTYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPVAALFTPLKERPDLPPIQYEPVLCSRTTCRAVLNPLCQVDYRAKLWACNFCYQRNQFPPTYAGISELNQPAELLPQFSSIEYVVLRGPQMPLIFLYVVDTCIEDEDLQALKESMQMSLSLLPPTALVGLITFGRMVQVHELGCEGISKSYVFRGTKDLSAKQLQEMLGLSKVPVTQAT------RGPQVQQP--PPSNRFLQPVQKIDMNLTDLLGELQRDPWPVPQGKRPLRSSGVALSIAVGLLECTFPNTGARIMMFIGGPATQGPGMVVGDELKTPIRSWHDIEKDNAKYVKKGTKHFEALANRAATTGHVIDIYACALDQTGLLEMKCCPNLTGGYMVMGDSFNTSLFKQTFQRVFTKDIHGQFKMGFGGTLEIKTSREIKISGAIGPCVSLNSKGPC-VSENEIGTGGTCQWKICGLSPTTTLAIYFEVVNQHNAPIPQGGR---------GAVQFVTQYQHSSGQRRIRVTTIARNWADAQTQIQNIAASFDQEAAAILMARLAIYRAETEEGPDVLRWLDRQLIRLCQKFGEYHKDDPNSFRFSETFSLYPQFMFHLRRSPFLQVFNNSPDESSYYRHHFMRQDLTQSLIMIQPILYAYSFSGPPEPVLLDSSSILADRILLMDTFFQILIYHGETIAQWRKSGYQDMPEYENFRHLLQAPVDDAQEILHSRFPMPRYIDTEHGGSQARFLLSKVNPSQTHNNMYAWGQE--------SGAPILTDDVSLQVFMDHLKKLAVSSAA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01405-1", "uniprot_id": "SC23A_MOUSE", "id": "Q01405-1", "name": "Protein transport protein Sec23A", "aln": "------MTTYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPVAALFTPLKERPDLPPIQYEPVLCSRTTCRAVLNPLCQVDYRAKLWACNFCYQRNQFPPTYAGISELNQPAELLPQFSSIEYVVLRGPQMPLIFLYVVDTCIEDEDLQALKESMQMSLSLLPPTALVGLITFGRMVQVHELGCEGISKSYVFRGTKDLSAKQLQEMLGLSKVPVTQAT------RGPQVQQP--PPSNRFLQPVQKIDMNLTDLLGELQRDPWPVPQGKRPLRSSGVALSIAVGLLECTFPNTGARIMMFIGGPATQGPGMVVGDELKTPIRSWHDIEKDNAKYVKKGTKHFEALANRAATTGHVIDIYACALDQTGLLEMKCCPNLTGGYMVMGDSFNTSLFKQTFQRVFTKDIHGQFKMGFGGTLEIKTSREIKISGAIGPCVSLNSKGPC-VSENEIGTGGTCQWKICGLSPTTTLAIYFEVVNQHNAPIPQGGR---------GAVQFVTQYQHSSGQRRIRVTTIARNWADAQTQIQNIAASFDQEAAAILMARLAIYRAETEEGPDVLRWLDRQLIRLCQKFGEYHKDDPNSFRFSETFSLYPQFMFHLRRSPFLQVFNNSPDESSYYRHHFMRQDLTQSLIMIQPILYAYSFSGPPEPVLLDSSSILADRILLMDTFFQILIYHGETIAQWRKSGYQDMPEYENFRHLLQAPVDDAQEILHSRFPMPRYIDTEHGGSQARFLLSKVNPSQTHNNMYAWGQE--------SGAPILTDDVSLQVFMDHLKKLAVSSAA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15436-1", "uniprot_id": "SC23A_HUMAN", "id": "Q15436-1", "name": "Protein transport protein Sec23A", "aln": "------MTTYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPVAALFTPLKERPDLPPIQYEPVLCSRTTCRAVLNPLCQVDYRAKLWACNFCYQRNQFPPSYAGISELNQPAELLPQFSSIEYVVLRGPQMPLIFLYVVDTCMEDEDLQALKESMQMSLSLLPPTALVGLITFGRMVQVHELGCEGISKSYVFRGTKDLSAKQLQEMLGLSKVPLTQAT------RGPQVQQP--PPSNRFLQPVQKIDMNLTDLLGELQRDPWPVPQGKRPLRSSGVALSIAVGLLECTFPNTGARIMMFIGGPATQGPGMVVGDELKTPIRSWHDIDKDNAKYVKKGTKHFEALANRAATTGHVIDIYACALDQTGLLEMKCCPNLTGGYMVMGDSFNTSLFKQTFQRVFTKDMHGQFKMGFGGTLEIKTSREIKISGAIGPCVSLNSKGPC-VSENEIGTGGTCQWKICGLSPTTTLAIYFEVVNQHNAPIPQGGR---------GAIQFVTQYQHSSGQRRIRVTTIARNWADAQTQIQNIAASFDQEAAAILMARLAIYRAETEEGPDVLRWLDRQLIRLCQKFGEYHKDDPSSFRFSETFSLYPQFMFHLRRSSFLQVFNNSPDESSYYRHHFMRQDLTQSLIMIQPILYAYSFSGPPEPVLLDSSSILADRILLMDTFFQILIYHGETIAQWRKSGYQDMPEYENFRHLLQAPVDDAQEILHSRFPMPRYIDTEHGGSQARFLLSKVNPSQTHNNMYAWGQE--------SGAPILTDDVSLQVFMDHLKKLAVSSAA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SZE5-1", "uniprot_id": "SC23A_DANRE", "id": "Q7SZE5-1", "name": "Protein transport protein Sec23A", "aln": "------MATFQEFIQQNEDRDGVRFSWNVWPSSRLEATRMVVPVASLFTPLKERPDLPPIQYEPVLCSRATCRAVLNPLCQVDYRAKLWACNFCYQRNQFPPTYAGISEVNQPAELLPQFSTIEYVVQRGPQMPLNFLYVVDTCMEDDDLQALKESLQMSLSLLPPTALVGLITFGRMVQVHELGCEGISKSYVFRGTKDLNAKQLQEMLGLTKPAAAQAG------RGPQQPQV--PPSNRFLQPVQKIDMNLTDLLGELQRDPWPVTQGKRPLRSLGVALSIAVGLLECTFPNTGARIMAFIGGPATQGPGMVVGDELKTPIRSWHDIEKDNAKFMKKATKHYEALANRAAANGHIIDIYACALDQTGLLEMKCCTNYTGGYMVMADSFNTSLFKQTFQRVFTKDVQGCFKMALAGTLEIKTSREIKISGAIGPCVSLNAKGPC-VSENEMGTGGTSQWKICGLDPNTTLGFYFEVVNQHNAPIPQGGR---------GAIQYVTQYQHSSGQRRIRVTTIARNWADAQSQIQSIAASFDQEAAAILMARLAVYKAETEEGPDVLRWLDRQLIRLCQKFGDYHKEDPNSFRFSETFSLYPQFMFHLRRSPFLQVFNNSPDESTYYRHQFMRQDLTQSLIMVQPILYAYSFNGPPEPVLLDSSSILPDRILLMDTFFQILIYHGETVSQWRKAGYQDMPEYENFRHLLQAPVDDAQELLHTRFPMPRYIDTEHGGSQARFLLSKVNPSQTHNNMYAWGQE--------SGAPILTDDVSLQVFMDHLKKLAVSSAA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I5ZKS5-1", "uniprot_id": "A0A8I5ZKS5_RAT", "id": "A0A8I5ZKS5-1", "name": "Protein transport protein SEC23", "aln": "------MATYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVLCSRPTCKAILNPLCQVDYRAKLWACNFCFQRNQFPPAYAGISEVNQPAELMPQFSTIEYMIQRGARSPLIFLYVVDTCLEEDDLQALKESLQMSLSLLPPDALVGLITFGRMVQVHELSCEGISKSYVFRGTKDLTAKQIQEMLGLTKSAMPVQQ------VRPGQPQEQSAVSSRFLQPVHKIDMNLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQGPGMVVGDELKTPIRSWHDIEKDNARFMKKATKHYEMLANRTATNGHCIDIYACALDQTGLLEMKCCPNLTGGLMVMGDSFNTSLFKQTFQRIFSKDFNGDFRMAFGATLEVKTSRELKIAGAIGPCVSLNVKGPC-VSENELGVGGTSQWKICGLDPSSTLGIYFEVVNQHNAPIPQGGR---------GAIQFVTQYQHSSTQKRIRVTTIARNWADAQSQLRHIEAAFDQEAAAVLMARLGVFRAESEEGPDVLRWLDRQLIRLCQKFGQYNKEDPTSFRLSDSFSLYPQFMFHLRRSPFLQVFNNSPDESSYYRHHFARQDLTQSLIMIQPILYSYSFHGPPEPVLLDSSSILADRILLMDTFFQIVIYLGETIAQWRKAGYQDMPEYENFKHLLQAPLDDAQEILQARFPMPRYINTEHGGSQARFLLSKVNPSQTHNNLYAWGQE--------TGAPILTDDVSLQVFMDHLKKLAVSSAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D662-1", "uniprot_id": "SC23B_MOUSE", "id": "Q9D662-1", "name": "Protein transport protein Sec23B", "aln": "------MATYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVLCSRPTCKAILNPLCQVDYRAKLWACNFCFQRNQFPPAYAGISEVNQPAELMPQFSTIEYMIQRGARSPLIFLYVVDTCLEEDDLQALKESLQMSLSLLPPDALVGLITFGRMVQVHELSCEGISKSYVFRGTKDLTAKQIQEMLGLTKSAMPVQQ------ARPAQPQEQPFVSSRFLQPIHKIDMNLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQGPGMVVGDELKTPIRSWHDIEKDNARFMKKATKHYEMLANRTATNGHCIDIYACALDQTGLLEMKCCPNLTGGHMVMGDSFNTSLFKQTFQRIFSKDFNGDFRMAFGATLDVKTSRELKIAGAIGPCVSLNVKGPC-VSENELGVGGTSQWKICGLDPSSTLGIYFEVVNQHNAPVPQGGR---------GAIQFVTQYQHSSTQKRIRVTTIARNWADAQSQLRHIEAAFDQEAAAVLMARLGVFRAESEEGPDVLRWLDRQLIRLCQKFGQYNKEDPTSFRLSDSFSLYPQFMFHLRRSPFLQVFNNSPDESSYYRHHFARQDLTQSLIMIQPILYSYSFHGPPEPVLLDSSSILADRILLMDTFFQIVIYLGETIAQWRKAGYQDMPEYENFKHLLQAPLDDAQEILQARFPMPRYINTEHGGSQARFLLSKVNPSQTHNNLYAWGQE--------TGAPILTDDVSLQVFMDHLKKLAVSSAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15437-1", "uniprot_id": "SC23B_HUMAN", "id": "Q15437-1", "name": "Protein transport protein Sec23B", "aln": "------MATYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVLCSRPTCKAVLNPLCQVDYRAKLWACNFCFQRNQFPPAYGGISEVNQPAELMPQFSTIEYVIQRGAQSPLIFLYVVDTCLEEDDLQALKESLQMSLSLLPPDALVGLITFGRMVQVHELSCEGISKSYVFRGTKDLTAKQIQDMLGLTKPAMPMQQ------ARPAQPQEHPFASSRFLQPVHKIDMNLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQGPGMVVGDELKIPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIYACALDQTGLLEMKCCANLTGGYMVMGDSFNTSLFKQTFQRIFTKDFNGDFRMAFGATLDVKTSRELKIAGAIGPCVSLNVKGPC-VSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQHNTPIPQGGR---------GAIQFVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLMARLGVFRAESEEGPDVLRWLDRQLIRLCQKFGQYNKEDPTSFRLSDSFSLYPQFMFHLRRSPFLQVFNNSPDESSYYRHHFARQDLTQSLIMIQPILYSYSFHGPPEPVLLDSSSILADRILLMDTFFQIVIYLGETIAQWRKAGYQDMPEYENFKHLLQAPLDDAQEILQARFPMPRYINTEHGGSQARFLLSKVNPSQTHNNLYAWGQE--------TGAPILTDDVSLQVFMDHLKKLAVSSAC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z6P7-1", "uniprot_id": "A0A8M6Z6P7_DANRE", "id": "A0A8M6Z6P7-1", "name": "Protein transport protein SEC23", "aln": "MVVRAVMATYQEFIQQNEDRDGIRCSWNLWPSSRLEATRLVVPVSCLYTPLKERPDLPPVQYEPVLCTRANCKAVLNPLCQVDFRAKIWACNFCFQRNSFPPSYAGISEVNQPAELMPQFSTIEYIVQRGPPTPLIFLYLVDTCLEEEDLQALKESLQMSLSLLPPNALVGLITFGRMIQVHELSCEGIAKSYVFRGTKELAPKQIQEMLGLMKPATSGQQ------GKPLAPHD-AAASCRFLQPVQMVDMNLTDLLGELQRDPWPVPQGKRPLRSTGIALSIAVGLLEGTFPNTGARVMLFTGGPPTQGPGMVVGDELKTPIRSWHDIQKDNARHLKKATKYYEALANRAAVNGHSVDIYACALDQTGLLEMKCLSNLTGGHIVMGDSFNTSLFKQTFQRVFNKDYNGEFRMAFGATLEVKTSRELKVSGAIGPCVSLNTKGPC-VSDNEMGVGGTCQWKICSLSPATTLAMYFEVVNQHNAPVPQGGR---------GVVQFVTQYQHSNTQRRIRVTTIARNWADAQSQIQHIESSFDQEASAVLMARLGVFRAESEEGPDVLRWLDRQLIRLCQKFGQFNKDDPNSFRLSESLSLYPQFMFHLRRSPFLQVFNNSPDESSYYRHHFVRQDLTQSLIMIQPILYSYSFHGPPEPVLLDSSSILPDRILLMDTFFQLVIYHGETIAQWRKAGYQEMAEYENFKQLLQAPLDDAQEILQTRFPMPRYIDTEHGGSQARFLLSKVNPSQTHNNLYAWGQE--------SGAPILTDDVSLQVFMDHLKKLAVSSSA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K5Z8-1", "uniprot_id": "A0A0B4K5Z8_DROME", "id": "A0A0B4K5Z8-1", "name": "Protein transport protein SEC23", "aln": "------MTTYEEFIQQNEDRDGVRLTWNVWPSSRIEASRLVVPLACLYQPLKERPDLPPIQYEPVLCTRSNCRAILNPLCQVDYRAKLWVCNFCFQRNPFPPQYAAISEQHQPAELIPGFSTIEYTITRAPTMPPVFIFLVDTCMDEEELDALKDSLQMSLSLLPTNALVGLITFGKMIQVHELGAEGCSKSYVFRGTKDLTAKQVQDMLGIGRGAAPGPQQQQHLPGQPAGAAAPVPPAHRFLQPIGQCDAALGDLLSELQRDPWPVPQGKRYLRSTGAALSIAVGLLECTYPNTGGRIMTFVGGPCSQGPGQVVDDELKHPIRSHHDIHKDNVRFMKKAIKHYDALALRAATNGHSVDIYSCALDQTGLLEMKQLCNSTGGHMVMGDSFNSSLFKQTFQRVFARDGRNDLKMAFNATLEVKCSRELKISGGIGSCVSLNVKSPS-VSDVEIGMGNTVQWKLCTLNPSSTVAYFFEVVNQHAAPIPQGGR---------GCIQFITQYQHPSGQRRIRVTTLARNWADATSNVHHISAGFDQEAAAVLMARMVVYRAETDEGPDILRWVDRQLIRLCQKFGEYSKDDPNSFRLSQNFSLFPQFMYHLRRSQFLQVFNNSPDETTFYRHMLMREDLTQSLIMIQPILYSYSFNGPPEPVLLDTASIQADRILLMDTFFQILIYHGETIAQWRALKYQDMPEYENFKQLLQAPVDDAQEILQTRFPMPRYIDTEHGGSQARFLLSKVNPSQTHNNMYAYGQAPIGQVTVDGGAPVLTDDVSLQLFMEHLKKLAVSTTT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15303-1", "uniprot_id": "SEC23_YEAST", "id": "P15303-1", "name": "Protein transport protein SEC23", "aln": "----------MDFET-NEDINGVRFTWNVFPSTRSDANSNVVPVGCLYTPLKEYDELNVAPYNPVVCSGPHCKSILNPYCVIDPRNSSWSCPICNSRNHLPPQYTNLSQENMPLELQS--TTIEYITNKPVTVPPIFFFVVDLTSETENLDSLKESIITSLSLLPPNALIGLITYGNVVQLHDLSSETIDRCNVFRGDREYQLEALTEMLTGQKPTGPGGAAS---HLPNAMNKVTPFSLNRFFLPLEQVEFKLNQLLENLSPDQWSVPAGHRPLRATGSALNIASLLLQGCYKNIPARIILFASGPGTVAPGLIVNSELKDPLRSHHDIDSDHAQHYKKACKFYNQIAQRVAANGHTVDIFAGCYDQIGMSEMKQLTDSTGGVLLLTDAFSTAIFKQSYLRLFAKDEEGYLKMAFNGNMAVKTSKDLKVQGLIGHASAVKKTDANNISESEIGIGATSTWKMASLSPYHSYAIFFEIANTAANSNPMMSAPGSADRPHLAYTQFITTYQHSSGTNRIRVTTVANQLLPFG--TPAIAASFDQEAAAVLMARIAVHKAETDDGADVIRWLDRTLIKLCQKYADYNKDDPQSFRLAPNFSLYPQFTYYLRRSQFLSVFNNSPDETAFYRHIFTREDTTNSLIMIQPTLTSFSMEDDPQPVLLDSISVKPNTILLLDTFFFILIYHGEQIAQWRKAGYQDDPQYADFKALLEEPKLEAAELLVDRFPLPRFIDTEAGGSQARFLLSKLNPSDNYQDMARGGST-----------IVLTDDVSLQNFMTHLQQVAVSGQA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* **: :*:* :**::**:* :*. ***:..* **** :* *:**:*: . *:::*** * :* * . * * :* .** :** * :*: : * ** . ::*** : * *:::** : ::*::**:*: ******. **:****:*.::*:*:*..* :. **** :: : : :** : . . **: *: : * :** :*. * *.*. *:* **: * **.** **: : * .*:: * .** : .** :*..*** *:** ***..*:.:. **. *.:: :* *.*..** :**:: . ** *: *** : *** ::: *:*.:::***:: *:* :* .. ::*.: ..: :* *:::*: * ** . ::: ... :*: *:* * * **:. *.* : . :**:.* . * . . *::* ***.. .******:*.: * :.*****:*:****: :.:**:::*.*::**:** **:****:.:: *:** ***:: .:**:*** ::**** **.********:::*** : *:* *:****:** * ::*: . *:*****: *: .: ***:**** ::** ** ::*** **: .:* :*: **: * :* *:* ***:**:*:** ***********:***:.:::: *. :******** ** **:::*** ", "identical_positions": 308, "similar_positions": 234, "identity": "38.64%" }, { "cls_id": "homologset.agr.SGD:S000006386", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62306-1", "uniprot_id": "RUXF_HUMAN", "id": "P62306-1", "name": "Small nuclear ribonucleoprotein F", "aln": "------MS--LPLNPKPFLNGLTGKPVMVKLKWG-MEYKGYLVSVDGYMNMQLANTEEYIDGALSGHLGEVLIRCNNVLYIRGVEEEEEDGEMRE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62307-1", "uniprot_id": "RUXF_MOUSE", "id": "P62307-1", "name": "Small nuclear ribonucleoprotein F", "aln": "------MS--LPLNPKPFLNGLTGKPVMVKLKWG-MEYKGYLVSVDGYMNMQLANTEEYIDGALSGHLGEVLIRCNNVLYIRGVEEEEEDGEMRE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AAT4-1", "uniprot_id": "D4AAT4_RAT", "id": "D4AAT4-1", "name": "Small nuclear ribonucleoprotein F", "aln": "------MS--LPLNPKPFLNGLTGKPVMVKLKWG-MEYKGYLVSVDGYMNMQLANTEEYIDGALSGHLGEVLIRCNNVLYIRGVEEEEEDGEMRE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q24297-1", "uniprot_id": "RUXF_DROME", "id": "Q24297-1", "name": "Small nuclear ribonucleoprotein F", "aln": "------MSAGMPINPKPFLNGLTGKPVLVKLKWG-QEYKGFLVSVDGYMNMQLANTEEVIEGSVTGNLGEVLIRCNNVLYIKGMEDDDEEGEMRD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54999-1", "uniprot_id": "RUXF_YEAST", "id": "P54999-1", "name": "Small nuclear ribonucleoprotein F", "aln": "MSESSDISAMQPVNPKPFLKGLVNHRVGVKLKFNSTEYRGTLVSTDNYFNLQLNEAEEFVAGVSHGTLGEIFIRCNNVLYIR---------ELPN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *:******:**..: * ****:. **:* ***.*.*:*:** ::** : * * ***::*********: *: :", "identical_positions": 43, "similar_positions": 21, "identity": "45.26%" }, { "cls_id": "homologset.agr.SGD:S000006387", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A8N1-1", "uniprot_id": "D4A8N1_RAT", "id": "D4A8N1-1", "name": "Dolichol-phosphate mannosyltransferase subunit 1", "aln": "MASTGASRSLAASQRPPQGRSSRQDKYSVLLPTYNERENLP-LIVWLLVKSFSESAINYEIIIIDDGSPDGTREVAEQLEKIYGPDRILLRPREKKLGLGTAYIHGIKHATGNYVIIMDADLSHHPKFIPEFIRKQKEGNFDIVSGTRYK-GNGGVYGWDLKRKIISRGANFITQILLRPGASDLTGSFRLYRKEVLQKLIEKCVSKGYVFQMEMIVR---ARQMDYTVGEVPISFVDRVYGESKLGGNEIVSFLKGLLTLFATT-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70152-1", "uniprot_id": "DPM1_MOUSE", "id": "O70152-1", "name": "Dolichol-phosphate mannosyltransferase subunit 1", "aln": "MASTGASRSLAASPRPPQGRSSRQDKYSVLLPTYNERENLP-LIVWLLVKSFSESAINYEIIIIDDGSPDGTREVAEQLAEIYGPDRILLRPREKKLGLGTAYIHGIKHATGNYVIIMDADLSHHPKFIPEFIRKQKEGNFDIVSGTRYK-GNGGVYGWDLKRKIISRGANFITQILLRPGASDLTGSFRLYRKEVLQKLIEKCVSKGYVFQMEMIVR---ARQMNYTIGEVPISFVDRVYGESKLGGNEIVSFLKGLLTLFATT-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60762-1", "uniprot_id": "DPM1_HUMAN", "id": "O60762-1", "name": "Dolichol-phosphate mannosyltransferase subunit 1", "aln": "MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLP-LIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRILLRPREKKLGLGTAYIHGMKHATGNYIIIMDADLSHHPKFIPEFIRKQKEGNFDIVSGTRYK-GNGGVYGWDLKRKIISRGANFLTQILLRPGASDLTGSFRLYRKEVLEKLIEKCVSKGYVFQMEMIVR---ARQLNYTIGEVPISFVDRVYGESKLGGNEIVSFLKGLLTLFATT-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIU7-1", "uniprot_id": "DPM1_DROME", "id": "Q9VIU7-1", "name": "Dolichol-phosphate mannosyltransferase subunit 1", "aln": "MPTNG-------------------HKYSILMPTYNEKDNLP-IIIWLIVKYMKASGLEYEVIVIDDGSPDGTLDVAKDLQKIYGEDKIVLRPRGSKLGLGTAYIHGIKHATGDFIVIIDADLSHHPKFIPEFIKLQQEGNYDIVSGTRYA-GNGGVFGWDFKRKLISRGANFLSQVLLRPNASDLTGSFRLYKKDVLEKCIASCVSKGYVFQMEMLVR---ARQHGYTIAEVPITFVDRIYGTSKLGGTEIIQFAKNLLYLFATT-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14020-1", "uniprot_id": "DPM1_YEAST", "id": "P14020-1", "name": "Dolichol-phosphate mannosyltransferase", "aln": "----------------------MSIEYSVIVPAYHEKLNIKPLTTRLFAGMSPEMAKKTELIFVDDNSQDGSVEEVDALAHQGYNVRIIVRTNER--GLSSAVLKGFYEAKGQYLVCMDADLQHPPETVPKLFESLHDHAFTLG--TRYAPGVGIDKDWPMYRRVISSTARMMARPLT-IASDPMSGFFGLQKKYLENCNPRDINSQGFKIALELLAKLPLPRDPRVAIGEVPFTFGVRTEGESKLSGKVIIQYLQQLKELYVFKFGANNLILFITFWSILFFYVCYQLYHLVF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**:::*:*:*: *: : *:. . : *:*.:**.* **: : .. * . :*::*.. **.:* ::*: .*.*:::: :****.* *: :*:::. :: : : *** * * .* : *::** *.:::: * :. ::* * * :* : : . *:*: : :*::.: .*: ::.***::* * * ***.*. *:.: : * *:. . ", "identical_positions": 62, "similar_positions": 91, "identity": "21.09%" }, { "cls_id": "homologset.agr.SGD:S000006388", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AEH9-1", "uniprot_id": "D4AEH9_RAT", "id": "D4AEH9-1", "name": "Glycogen debranching enzyme", "aln": "------------------------------------------------------------------------------------------MEHSKQIRILLLNEMEKLEKTLFRLEQGFELQFRLGPTLQGKAVTVYTNYPFPGEAFNREKFRSLDWEN-----------PTEREDDSDKYCKVHLQQSGSFQYYFLQG-QEKSGGG------YIVVDPILRVG--ADNHVLPLDCVTLQTFLAKCLGPFDEWESRLRVAKESGYNMIHFTPLQALGLSRSCYSLADQLELNPDFSRP-NRRYTWDDVGQLVEKLKREWNILCITDVVYNHTAANSKWIHEHPESAYNLVNSPHLKPAWVLDRALWHLSCDVADGKYREKGVPALIENDHHMNCIRKIIWEDIFPRIQLWEFFQVDVQKAVEQFRRLLSQ-ENRRVTKSEPK--------EHLKIIQD----PEFRRLGCAVDMNIALATFIPHD----NGPAA-IEECCNWFRKRLEELNSEKHHLTSCHQEQAVNCLLGNVFYERLAGHGPKLGPVTRKYPLVTRYFTFPFEEMALSAEESLLHRPDKACFLMAHNGWVMG-DDPLRNFAE--PG-SNVYLRRELICWGDSVKLRYGNKPEDCPYLWAHMKKYTEITATHFQGVRLDNCHSTPLHVAEYMLDAARKLQPNLYVVAELFTGSEDLDNIFVTRLGISSLIREAMSAYNSHEEGRLVYRYGGEPVGSFVQPCL----------------------------------RPLMPAIAHALFMDITHDNECPIVHRSAYDALPSTTVVSMACCASGSTRGYDELVPHQISVVAEERFYTKWNPGASPSDTGDVSIHSGIIAARCAINRLHQELGAKGF----IQVYVDQVDEDIVAVTRHSPSIHQSVVAVSRTAFRNPKTSFYSKEVPQMCIPGKIEEVVLEARTIERN------TKPYRKDENSINGMPNMTVELR-ERIQLHESKIVKQAGVATKGPNEYIQEIEFENLSPGSVIIFRVSLDPHAQVAVGILRNHLTQFSSHFKSGSLAVDNSDPILKIPFASIASKLTLAELNQVLYRCESEEQ---EDGGGCYDIPNWSSLKYAGLQGLMSVLAEIRPKNDLGHPFCENLRSGDWMIDYVSGRLISR--SGSIAEVGKWLQAMFFYLKQIPRYLIPCYFDAILIGAYTTLLDVAWKQMSSFVQNGSTFVKHLSLGSVQMCGVGKCPCLPLLSPSLLDVPCRLNEITKEKEQCCASLAAGLPHFSSGLFRCWGRDTFIALRGMLLVTGRYLEARNIILAFACTLRHGLIPNLLGEGTYARYNCRDAVWWWLQCIQDYCKMVPNGLDILKCPVSRMYPTDDS--APLPAGTL--DQPLFEVIQEAMQRHMQGIQFRERNAGPQIDRNMKDEGFNITVGVDEETGFVYGGNRFNCGTWMDKMGESDRARNRGIPATPRDGSAVEIVGLCKSAVRWLLELSKKNIFPYHEVRVRR-HGKVVAVSYDEWNRKIQNSFEKLFHVSEDPSDPNEKHPNL---VHKRGIYKDSYGASSPWCDYQLRPNFTIAMVVAPELFTAEKAWKALEIAEGKLLGPLGMKTLDPDDMVYCGVYDNALDNDNYNLARGFNYHQGPEWLWPIGYFLRAKLYFSKMMGPETAAKT--------VFLVKNVLSRHYVHLERSPWKGLPELTNENGQYCPFSCETQAWSMAAVLETLYDL--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F8VPN4-1", "uniprot_id": "F8VPN4_MOUSE", "id": "F8VPN4-1", "name": "Glycogen debranching enzyme", "aln": "------------------------------------------------------------------------------------------MEHSKQIRILLLNEMEKLEKTLFRLEQGFELQFRLGPTLQGKAVTVYTNYPLPGEAFNREKFRSLDWEN-----------PTEREDDSDKYCKLHLQQSGSFQYYFLQG-NEKSGGG------YIVVDPILRIG--VDNHVLPLDCVTLQTFLAKCLGPFDEWESRLRVAKESGYNMIHFTPLQTLGLSRSCYSLADQLELNPDFSRP-SKRYTWSDVGQLVEKLKREWNILCITDVVYNHTATNSKWILEHPESAYNLVNSPHLKPAWVLDRALWHFSCDVADGKYREKGVPALIENDQHMNCIRKIIWEDIFPRIQLWEFFQVDVHKAVEQFRRLLSQ-ENRRVTKSEPK--------EHLKIIQD----PEYRRRGCAVDMDTALATFIPHD----NGPAA-IEECCNWFRKRLEELNSEKHHLTSCHQEQAVNCLLGNVFYERLAGHGPKLGPVTRKYPLVTRYFTFPFGEMALSAEEALIHLPDKACFLMAHNGWVMG-DDPLRNFAE--PG-SDVYLRRELICWGDSVKLRYGNKPEDCPYLWAHMKKYTEITATHFQGVRLDNCHSTPLHVAEYMLDAARKLQPNLYVVAELFTGSEELDNIFVTRLGISSLIREAMSAYNSHEEGRLVYRYGGEPVGSFVQPCL----------------------------------RPLMPAIAHALFMDITHDNECPIVHRSAYDALPSTTVVSMACCASGSTRGYDELVPHQISVVAEERFYTKWNPGASPADTGDVNVHSGIIAARCAINRLHQELGAKGF----IQVYVDQVDEDIVAVTRHSPSIHQSVVAVSRTAFRNPKTSFYSKEVPQMCIPGKIEEVVLEARTIERN------TKPYKKDENSINGMPNMTVELR-EHIQLHESKIVRQAGVATKGPNEYIQEIEFENLSPGSVIIFRVSLDPHAQVAVGILRNHLTQFSSHFKSGSLAVDNADPILKIPFASIASKLTLAELNQVLYRCESEEQ---EDGGGCYDIPNWSSLKYAGLQGLMSVLAEIRPKNDLGHPFCENLRSGDWMIDYVSGRLISR--SGSIAEVGKWLQAMFFYLKQIPRYLIPCYFDAILIGAYTTLLDVAWKQMSSFVQNGSTFVKHLSLGSVQMCGVGKCPCLPLLSPSLLDVPCRLNEITKEKEQCCASLAAGLPHFSSGLFRCWGRDTFIALRGMLLVTGRYLEARNIILAFASTLRHGLIPNLLGEGTYARYNCRDAVWWWLQCIQDYCRTVPNGLDILKCPVSRMYPTDDS--APLPAGTL--DQPLFEVIQEAMQRHMQGIQFRERNAGPQIDRNMKDEGFNITAGIDEETGFVYGGNRFNCGTWMDKMGESDRARNRGIPATPRDGSAVEIVGLCKSAVRWLLELSKKNIFPYHEVRVKR-HGKVVAVSYDEWNRKIQNNFEKLFHVSEDPSDPNEKHPNL---VHKRGIYKDSYGASSPWCDYQLRPNFTIAMVVAPELFTAEKAWKALEIAEKKLLGPLGMKTLDPDDMVYCGVYDNALDNDNYNLARGFNYHQGPEWLWPIGYFLRAKLYFSKMMGPETAAKT--------VFLVKNVLSRHYVHLERSPWKGLPELTNENGQYCPFSCETQAWSMAVVLETLYDL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35573-1", "uniprot_id": "GDE_HUMAN", "id": "P35573-1", "name": "Glycogen debranching enzyme", "aln": "------------------------------------------------------------------------------------------MGHSKQIRILLLNEMEKLEKTLFRLEQGYELQFRLGPTLQGKAVTVYTNYPFPGETFNREKFRSLDWEN-----------PTEREDDSDKYCKLNLQQSGSFQYYFLQG-NEKSGGG------YIVVDPILRVG--ADNHVLPLDCVTLQTFLAKCLGPFDEWESRLRVAKESGYNMIHFTPLQTLGLSRSCYSLANQLELNPDFSRP-NRKYTWNDVGQLVEKLKKEWNVICITDVVYNHTAANSKWIQEHPECAYNLVNSPHLKPAWVLDRALWRFSCDVAEGKYKEKGIPALIENDHHMNSIRKIIWEDIFPKLKLWEFFQVDVNKAVEQFRRLLTQ-ENRRVTKSDPN--------QHLTIIQD----PEYRRFGCTVDMNIALTTFIPHD----KGPAA-IEECCNWFHKRMEELNSEKHRLINYHQEQAVNCLLGNVFYERLAGHGPKLGPVTRKHPLVTRYFTFPFEEIDFSMEESMIHLPNKACFLMAHNGWVMG-DDPLRNFAE--PG-SEVYLRRELICWGDSVKLRYGNKPEDCPYLWAHMKKYTEITATYFQGVRLDNCHSTPLHVAEYMLDAARNLQPNLYVVAELFTGSEDLDNVFVTRLGISSLIREAMSAYNSHEEGRLVYRYGGEPVGSFVQPCL----------------------------------RPLMPAIAHALFMDITHDNECPIVHRSAYDALPSTTIVSMACCASGSTRGYDELVPHQISVVSEERFYTKWNPEALPSNTGEVNFQSGIIAARCAISKLHQELGAKGF----IQVYVDQVDEDIVAVTRHSPSIHQSVVAVSRTAFRNPKTSFYSKEVPQMCIPGKIEEVVLEARTIERN------TKPYRKDENSINGTPDITVEIR-EHIQLNESKIVKQAGVATKGPNEYIQEIEFENLSPGSVIIFRVSLDPHAQVAVGILRNHLTQFSPHFKSGSLAVDNADPILKIPFASLASRLTLAELNQILYRCESEEK---EDGGGCYDIPNWSALKYAGLQGLMSVLAEIRPKNDLGHPFCNNLRSGDWMIDYVSNRLISR--SGTIAEVGKWLQAMFFYLKQIPRYLIPCYFDAILIGAYTTLLDTAWKQMSSFVQNGSTFVKHLSLGSVQLCGVGKFPSLPILSPALMDVPYRLNEITKEKEQCCVSLAAGLPHFSSGIFRCWGRDTFIALRGILLITGRYVEARNIILAFAGTLRHGLIPNLLGEGIYARYNCRDAVWWWLQCIQDYCKMVPNGLDILKCPVSRMYPTDDS--APLPAGTL--DQPLFEVIQEAMQKHMQGIQFRERNAGPQIDRNMKDEGFNITAGVDEETGFVYGGNRFNCGTWMDKMGESDRARNRGIPATPRDGSAVEIVGLSKSAVRWLLELSKKNIFPYHEVTVKR-HGKAIKVSYDEWNRKIQDNFEKLFHVSEDPSDLNEKHPNL---VHKRGIYKDSYGASSPWCDYQLRPNFTIAMVVAPELFTTEKAWKALEIAEKKLLGPLGMKTLDPDDMVYCGIYDNALDNDNYNLAKGFNYHQGPEWLWPIGYFLRAKLYFSRLMGPETTAKT--------IVLVKNVLSRHYVHLERSPWKGLPELTNENAQYCPFSCETQAWSIATILETLYDL--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BAR0-1", "uniprot_id": "A0A8M2BAR0_DANRE", "id": "A0A8M2BAR0-1", "name": "Glycogen debranching enzyme", "aln": "-------------------------------------------------------------------------------------------MTAKQTRVMVLNDMEKLDRTLFRLDQGFELQFRLGPTLQGKHVRVYTNYPTEGERFDRQKFHALDWIN-----------PTAREDDSDKFCTLDLKISGSYQYYFGHGGDEKSGGG------YIVVDPVLRVG--ADNHVLPLDCITIQTYLSKCLGPLDEWSDRLRVAKEAGYNMIHFTPLQTLGESRSCYSLADQLELNPDFSPS-GQTYTWTDAGNLVEKLKNEWNMLCITDVVYNHTASNSKWIKKHPECGYNLVNSPHLKPAWVLDRALWHVTCAIADGKYEDRGLPALIQDHPHLHAIRGVLWQEVFPKIKLWEFFQVKIEALVEQFRALLQSGAKPDSSKTDGK--------KQLKIIQD----PQYRRFGNTVDMNTALELFVPNG----NSPGA-IEDCCNWLRRKLEELNGEQFHEVKHHQEQATNCIDGTVSYERLADHGPKLGPITRKHPLVTRYFTFPFEETTLEQDLELINQPEKSCHFLAHNGWVMG-DDPLRNFAE--PG-SNVYIRRELICWGDSVKLRYGSGPEDCPYLWAHMQKYTEITAKHFVGVRLDNCHSTPLHVAEAMLAAARSVRPNLYVIAELFTGSELIDNVFVNRLGITSLIREAMSAGDSHEEGRLVYRYGGEPVGAFLQPSL----------------------------------RPLVPSIAHAMFLDVTHDNECPIQIRSVYDSLPSSAIVSMACCATGSTRGYDELVPHQISVVSEERFYTKWSSQAKPSSPNEVNLQTGIIAGKLALNRLHQELAAKGF----SQVFVDQVDEDIVAVTRHCPSTHQSVVAVCRTAFKNPKHHRYTDEVPPMCIPGKIEEVVLEARTVERQ------TGTYKKDERSINGMPEYTVEIK-EHIQLADSKVVRQAGVTSRGRSEYVQEIVFEKLTPGSVIAFRVSLDPKSQELVGVLRNHLIQFNPLYKAGSVPDSNTPDILKSPLTQIMSKLTLADMNLLLFRCDSEEK---EDGGGCYNIPGWTPLKYGGLQGLLSVMAEIRPKNDLGHPFCDNLRQGDWMIDYVSNRLVSR--GGPLAEVGQWFQAMFAYLKHIPRYLIPCYFDAILVGAFTTALDATFRQMSSFVQDGSSFVKLLALGSVQMCGVGRFPALPPLSPALSDVPYRVNEITKEKEQCCVSMAAGLPHFSAGIFRCWGRDTFIALRGLLLVTGRHLEARNIILAFAGTLRHGLIPNLLGEGVGARFNCRDAVWWWLQCIQDYCTMVPNGTDILQCPVSRMYPTDDS--KPLTAGTV--DQLLYEVIHEAMERHIQGIEFRESNAGPQIDRNMRDEGFNIEAKVNPDTGFVYGGNRFNCGTWMDKMGESERARNKGIPATPRDGSAVEIVGLCKSTLRWLVELHKKGLFPYNTVKIQR-DGKQLSVAYDEWEMKIQKNFEKMFYVSHDPNDPNEKHPEL---VHKRGIYKDSYGASSPWCDYQLRPNFTIAMVVAPELFTVEHAWKALNMAEEKLLGPLGMKTLDPDDMVYCGVYDNSLDNDNYNLAKGFNYHQGPEWLWPIGYFLRAKIFFAKKMGKDTYDKT--------VYLVKNVLSRHNVHMERSSWKGLPELTNENGQYCSFSCETQAWSLAAVLEVLHDL--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32THB4-1", "uniprot_id": "A0AB32THB4_DANRE", "id": "A0AB32THB4-1", "name": "Glycogen debranching enzyme", "aln": "-------------------------------------------------MRSLSDVAARTAGDPDATFPVFKGHPKKST---------ASMFRGKQTRVLLLNDMESMERTLFRLEQGFELQFRLGPTLQGKSVHVHTNYPALYKKFVASSFRQLEWEN-----------PSGREDDSDKYCKLDLEIAGSYQYYFGCGNEQKTGGG------YIIVDPVLRVG--HERKILPLDCITVQTYLAKCLGPLDEWLDRLKVARETGYNMIHFTPLQKLGMSKSCYSIADQLELNPDFSPP-GKNYTWMDVGNLTEKLKKEWNMICITDVVYNHTAANSKWIRLHPECGYNLVNSPHLKPAWLLDRALWHFSCAIADGKYSDGGLPPLIENEKHITILKGLLWTEVFTHLKLWEFLQVNVEKAVEQFRKVLQAGNKPVGPELEGK--------PKLKVIQD----SQFRRLSNTVDMQLALEMFGRHT----NGPKS-IEECCDWFKKSLEELNVECYKEMHSHHEKAIDCIVGTVCYERIAAHGPQLGPVTQTNPLVLRYFTFPFEDMTMEQESQLMQDPNNACHLLAHNGWVMG-DDPLRNFAE--AG-STVYLRRELVCWGDSVKLRYGDKPEDCPYLWAHMKKYTEITAKHFSGVRLDNCHSTPLHVAEYILAVARQHRPDLYVVAELFTGSEELDNVFMTRLGITSLIREAMSAGDSHEEGRLVYRFGGEPVGSFIQPNL----------------------------------RPLEPSIAHAMFLDVTHDNECPIQVRSAYDALPSSAIVSMACCASGSTRGYDELVPHQISVVKEERLYPKWNPDALPSSGREVNLHSGITAGKLALNKLHQELAENGF----TQVYVDQLDEDTVAVTRHCPSTHQSVVTVCRTAFKDPKTHQFRESLAPMYIPGKIEEVILEARTVERS------AESYVKDETFINGLPNYTVEIR-EHIQLKESQIVKQGDATTKGRSEFVEEILFEKLTPGSVIAFRVSLDPNSQKMVGYLRTQLSQFNRLFKSGSLTDSNVAGILKISLEFLISKLTLAELNVLLFRCDAEEQ---EDGGGCYNIPSWMPLKYGGLQGFVSVLSEIRPKNDLGHPFCDNLRQGNWILDYVSTRLINK--GGALREVGKWFKAVFSYLKHLPRYLVPCYFDAIIVGAYATAVDAVFNQMSSFVLNGSTLVKQLALGSVQMCGVGRVPALPHLSPELEDVPVRVNSATKQEEQCCVSIAAGLPHFSTGIFRCWGRDTFIALRGLMLLTGRHLEARDIILAFAGTMRHGLIPNLLGQGVAARYNCRDAVWWWLQCIQDYCTIVPSGTDILMCPVSRMYPTDDS--EAQALGTVAHDQPLYVLIQEAMQRHMQGIQFRERNAGPQIDWNMQHEGFNVEAKVNPETGFVYGGNGFNCGTWMDKMGESDKAHNKGVPATPRDGSAVEIVGLSKSAVRWLMMMNETGHFPYSSVKIHR-DGAEQLITYKEWNQRIQENFERFFYVSDDPADPNEQRPDL---VHKKCIYKDSHGASSPWCDYQLRPNFTIAMVVAPELFSVQRAWKALEIVETKLLGPLGMKTLDPDDLVYCGVYDNALDNDDYNRAKGFNYHQGPEWIWLVGYFLRAKLYFGRKMGQEKYNQS--------VYLVKNVLSRLHTHLERSPWKGLPELTNENGQYCPFSCETQAWSIATVLEALFDL--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2H8-1", "uniprot_id": "Q9W2H8_DROME", "id": "Q9W2H8-1", "name": "Glycogen debranching enzyme", "aln": "MRYQLFRWLYGLIATVDNEPLPLQIKSEEEAFGENKKKKQLASLENAISPGKLDSVAIRTVPSANANAMGNAGSAEIVSNQIIRRREMSTMGKETESHSIPISEGQDAEHILYRLKRGSKLSVHPDASLLGRKIVLYTNYPAEGQKFVRTEYRVLGWQLSNGKQITSVMHPEAHVVDTDIRSQVELNMSGTYHFYFRYLERPDTGCSGADGALYVQVEPTLHVGPPGAQKTIPLDSVRCQTVLAKLLGPLDTWEPKLRVAKEAGYNVIHFTPIQELGGSRSCYSLRDQLKVNSHFAPQKGGKISFEDVEKVIKKCRQEWGVASICDIVLNHTANESDWLLQHPDATYSCATCPYLRPAFLLDATFAQCGADIAEGSLEHVGVPAVIEQECHLEALKYQLHTSYMSKVNIHELYQCDVMKYVNEFMSQVRTREPPKNVANECRF-------QEIQLIQD----PQYRRLASTINFELALEIFNAFHGDCFDEESR-FRKCAETLRRHLDALNDRVRCEVQGYINYAIDNVLAGVRYERVQGDGPRVKEISEKHSVFMVYFTHTGTQGKSLTEIEADMYTKAGEFFMAHNGWVMGYSDPLRDFAEEQPGRANVYLKRELISWGDSVKLRFGRRPEDSPYLWQHMTEYVQTTARIFDGVRLDNCHSTPLHVAEYLLDAARKINPELYVVAELFTNSDYTDNVFVNRLGITSLIREALSAWDSHEQGRLVYRYGGVPVGGFQANSS----------------------------------RHEATSVAHALFLDLTHDNPSPVEKRSVYDLLPSAALVSMACCATGSNRGYDELVPHHIHVVDEERTYQEWG--------KGVDSKSGIMGAKRALNLLHGQLAEEGF----SQVYVDQMDPNVVAVTRHSPITHQSVILVAHTAFGYPSPNAGPTGIRPLRFEGVLDEIILEASLTMQSDKPFDRPAPFKKDPNVINGFTQFQLNLQ-EHIPLAKS-TVFQTQAYSDGNN---TELNFANLRPGTVVAIRVSMHPGPRTSF----DKLQKISAALRIGSGEEYS-------QLQAIVSKLDLVALSGALFSCDDEERDL-GKGGTAYDIPNFGKIVYCGLQGFISLLTEISPKNDLGHPLCNNLRDGNWMMDYISDRLTS---YEDLKPLSAWFKATFEPLKNIPRYLIPCYFDAIVSGVYNVLINQVNELMPDFIKNGHSFPQSLALSTLQFLSVCKSANLPGFSPALSPP---------KPPKQCVTLSAGLPHFSTGYMRCWGRDTFIALRGSMFLTGRYNEARFIIIGFGQTLRHGLIPNLLDSGSKPRFNCRDAIWWWMYCIKQYVEDAPKGAEILKDKVSRIFPYDDA--DAHAPGAF--DQLLFDVMQEALQVHFQGLQYRERNAGYEIDAHMVDQGFNNQIGIHPETGFVFGGNNFNCGTWMDKMGSSQKAGNKGRPSTPRDGSAVELVGLQYAVLRFMQSLAEKEVIPYTGVERKGPSGEVTKWSYKEWADRIKNNFDKYFFVSES------ETCSV---ANKKLIYKDSYGATQSWTDYQLRCNFPITLTVAPDLCNPQNAWRALERAKKYLLGPLGMKTMDPEDWNYRANYDNSNDSTDCTVAHGANYHQGPEWVWPIGFYLRARLIFAKKCG--HLDET--------IAETWAILRAHLRELQTSHWRGLPELTNDNGSYCGDSCRTQAWSVAAILEVLYDLHSLGADVA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06625-1", "uniprot_id": "GDE_YEAST", "id": "Q06625-1", "name": "Glycogen debranching enzyme", "aln": "---------------------------------------------------MNRSLLLRLSDTGEPITSCSYG------------------KGVLTLPPIPLPKDAPKDQPLYTVK----LLVSAGSPVARDGLVWTNCPPDHNTPFKRDKFYKKIIHS---------------SFHEDDCIDLNVYAPGSYCFYLSFRNDNEKLETTR--KYYFVALPMLYIN----DQFLPLNSIALQSVVSKWLG--SDWEPILSKIAAKNYNMVHFTPLQERGESNSPYSIYDQLQFDQEHFKS------PEDVKNLVEHIHRDLNMLSLTDIVFNHTANNSPWLVEHPEAGYNHITAPHLISAIELDQELLNFSRNLKS-----WGYPTELKNIEDLFKIMDGIKVHVLGSLKLWEYYAVNVQTALRDIKAHWNDESNESYSFPENIKDISSDFVKLASFVKDNVTEPNFGTLGERNSNRINVPKFIQLLKLINDGGSDDSESSLATAQNILNEVNLPLYREYDDDVSEILEQLFNRIKYLRLDDGGPKQGPVTVDVPLTEPYFTR-------------FKGKDGTDYALANNGWIWN-GNPLVDFAS---QNSRAYLRREVIVWGDCVKLRYGKSPEDSPYLWERMSKYIEMNAKIFDGFRIDNCHSTPIHVGEYFLDLARKYNPNLYVVAELFSGSETLDCLFVERLGISSLIREAMQAWSEEELSRLVHKHGGRPIGSYKFVPMDDFSYPADINLNEEHCFNDSNDNSIRCVSEIMIPKILTATPPHALFMDCTHDNETPFEKRTVEDTLPNAALVALCSSAIGSVYGYDEIFPHLLNLVTEKRHYDISTP--------TGSPSIGITKVKATLNSIRTSIGEKAYDIEDSEMHVHHQG-QYITFHRMDVKSGKGWYLIARMKFSD--NDDPNETLPPVVLNQSTCSLRFSYALERVG-------DEIPNDDKFIKGIPTKLKELEGFDISYDDSKKISTIKLPN-------------EFPQGSIAIFETQQN-----------GVDESLDHFIRSGALKATS--------------SLTLESINSVLYRSEPEEYDVSAGEGGAYIIPNFGKPVYCGLQGWVSVLRKIVFYNDLAHPLSANLRNGHWALDYTISRLNYYSDEAGINEVQNWLRSRFDRVKKLPSYLVPSYFALIIGILYGCCRLKAIQLMSRNIGKSTLFVQSLSMTSIQMVSRMKSTSILPG-------------------ENVPSMAAGLPHFSVNYMRCWGRDVFISLRGMLLTTGRFDEAKAHILAFAKTLKHGLIPNLLDAGRNPRYNARDAAWFFLQAVQDYVYIVPDGEKILQEQVTRRFPLDDTYIPVDDPRAFSYSSTLEEIIYEILSRHAKGIKFREANAGPNLDRVMTDKGFNVEIHVDWSTGLIHGGSQYNCGTWMDKMGESEKAGSVGIPGTPRDGAAIEINGLLKSALRFVIELKNKGLFKFSDVETQD----GGRIDFTEWNQLLQDNFEKRYYVPEDPSQDADYDVSAKLGVNRRGIYRDLYKSGKPYEDYQLRPNFAIAMTVAPELFVPEHAIKAITIADEVLRGPVGMRTLDPSDYNYRPYYNNGEDSDDFATSKGRNYHQGPEWVWLYGYFLRAFHHFHFKTSPRCQNAAKEKPSSYLYQQLYYRLKGHRKWIFESVWAGLTELTNKDGEVCNDSSPTQAWSSACLLDLFYDLWDAYEDDS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . :: *: :. * . ...: : . * * .: . * :.: .*:: :*: .. *. . * * :. : :**:.: *: ::* ** . * * .**::****:* * *.* **: :**:.: .. *. :: :: :.: .: .: *:* **** :* *: **:. *. ..*:* .* ** : . : . * *. ::: .: : : : ::: * .: :.:: : .::* .:: . . : * . ... :. :: :* . : : : * *: **: :: .: *** . . :*:***: . .:** :**. : .*::**:: ***.****:* ***.**** :* :* : .* * *.*:*******:**.* :* **. .*:***:****:.*: * :*: ****:******:.* ...* .***::.** *:*.: : .: .**:*:* **** *. *:. * **.:::*::...* ** ****:.** : :* *:* * . ** : ::. :: .:. :.: ::.*.: . : ::. * :. :.: * : : : .: :. :* *:* . ::. * .* : . :: *:: :... . .:. : *: . * * :. *: .: ** * .* **.: * **** :*:: :* ***.**:. ***.*.* :** ** : : *::: * :*::* **:*.** *: : . . *. : .. : : *:: ::*: . : . : : :::******* . :******.**:*** :: ***. **: *:.*. *::********. * .*:*.*** *::: .:::* .*.* .** *:* :* **: :. .. * :: * :. * :*:::** *** ::* * .:*** :. .**::.**. :**********.*::* . * *.*****:*:*: ** :.:*:: : :. : : * : : ** ::..*:: :.*... . .::: **:* : : ..: ***** **.*::.***:* :.* :*: .. * **:**:*:**.* * *:*. *. : ::* ********:* *::*** * . : * : * * **.****.:.. * *. ***** * :*: :.** ", "identical_positions": 382, "similar_positions": 442, "identity": "21.97%" }, { "cls_id": "homologset.agr.SGD:S000006390", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2I4-1", "uniprot_id": "A0A0G2K2I4_RAT", "id": "A0A0G2K2I4-1", "name": "", "aln": "MDASFFPESLFSDDQICSQEEETEGESTLGEDCDKDEAVDCAQEEWTLKDPTQSSRPGDVAVEDHTNLATAELEKQLQTKDSAPEQDFLARHTFMETQQVDAVTFEDVAVDFTQEEWTSLD--------PIQRTLYREVMLENYQNLATVG-GQLFKPSLISWLERKVELTVMEQGILQEWEMHLKTKRTALQQDRFWSDMSNGMQLGRELSGGELGDSI------QVGTVFSEDSCPQTYISTPSTEDTSACHLRGKDFLPPLKETSTEENILQLNQCVKP--------------LTLTPDVSQRMCTLEKSVECSDCGKTFVNELELQAHSSSHSENNLHK---PEECGQAFTHPVSHDGHVIPTEKKYYECKKCEKFFTHPVYLNIHVQSHTVEKPYDCKECGKAFTERSSLIVHL-----------------------------------------------------------------------------------------------------RQHTREKSYECKECGKTFIQPSRLTEHMR-SHTGEKPYQCDQCGNAFASSSYLTTHLRTHTGEKPFECNICGKAFTRSSYLLGHIRTHTGEKPYECKVCGKAFSGRSWLTIHLRKHTGERPYPCTECEKAFTSFAQLTEHIKTHTGEKPFRCKVCARTFRNSSCLKTHFRIHTGIKPYKCNYCGKDFTARSGLTKHVLIHNGEKPYECKECGKAFSTSSGLVEHI--------RIHTGEKPFECYQCGKALAHSSSLVGHLRTHTG---EKPFECNQCDKTFTRSSYLRIHMRTHTG-EKPYECKECG--KTFPERSCLTKHIRTHT-------------GERPYECKECGKGFISFAQLTVHIKTHSSERPFQCKVCTKSFRNSSSLETHFRIHTGVKPYKCSYCGKDFTARSGLTIHLRNHTG---------EKSYACQECGKAFSTSSGLIAHIRSHKG-EKPFECDHCGKAFASSSYLNVHLKIHTGEKPFQCTVCGKTFTC-SSYLPVH---------------MRTHTGEKPFQC--IICGKSFLWSSYLRVHMRIHTGEKP------YVCQYCGKAFTEHSGLNKHLRKHTGEKPYEYKDSGEAFTTSTDANEHETPHWGENL-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10076-1", "uniprot_id": "ZFP26_MOUSE", "id": "P10076-1", "name": "Zinc finger protein 26", "aln": "----------------------------------------------------------------------------------------------METQQVDAVTFEDVAVDFTQEEWTSLD--------PVQRNLYRDVMLENYQNLATVG-GQMFKPSLISWLEKKVELTVIEQGILQEWEMHLKTKRTALQQDRFWSDMSNGMQLGREHSGGEPGDPV------QVGAVFSEDSCPQTHSSTSNTGNTFACNLDGKDFQPLLKETSTEENIVQLNQCVKP--------------LIFTPDVSQKKCTPEKSVECSDCGETFVNQLELQTHSSSHREKNIHK---SEECGQASTHPISHGGHVIPTEKKYYECKKCEKFFTHPVYLNIHMQSHTVEKPYDCKECGKAFTERSSLIVHL-----------------------------------------------------------------------------------------------------RQHTREKSYECKECGKTFIQPSRLTEHMR-SHTGEKPYQCDQCGNAFASSSYLTTHLRTHTGEKPFECNICGKAFTRSSYLLGHIRTHTGEKPYECKVCGKAFSGRSWLTIHLRKHTGERPYPCTECEKAFTSFAQLTEHIKTHTGEKPFRCKVCARTFRNSSCLKTHFRIHTGIKPYKCNYCGKAFTARSGLTKHVLIHNGEKPYECKECGKAFSTSSGLVEHI--------RIHTGEKPFECYQCGKALAHSSSLVGHLRTHTG---EKPFECNQCDKTFTRSSYLRIHMRTHTG-EKPYECKECG--KTFPERSCLTKHIRTHT-------------GERPYECKECGKGFISFAQLTVHIKTHSSERPFQCKVCTKSFRNSSSLETHFRIHTGVKPYKCSYCGKAFTARSGLTIHLRNHTG---------EKSYACQECGKAFSTSSGLIAHIRSHKG-EKPFECDHCGKAFASSSYLNVHLKIHTGEKPFQCTVCGKTFTC-SSYLPVH---------------MRTHTGEKPFQC--IICGKSFLWSSYLRVHMRIHTGEKP------YVCQYCGKAFTEHSGLNKHLRKHTGEKPYEYKECGENFTTSADANEHETPHWGENL-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62513-1", "uniprot_id": "ZN260_MOUSE", "id": "Q62513-1", "name": "Zinc finger protein 260", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLESLQPE----------------SHLLHD-----------------------------------------------------------------------------------------------------EPDPGESVYECNECKETFSLEQNFVEHKK-THSGEKSPECTGCGEESSQASSLTLHLRSRPRRESYKCGECGKAFSQRGNFLSHQKQHTEERPSESKKT-------------------------------------------------PVPMTTTVRNQRN---------------------------------------TGNKPYACKECGKAFNGKSYLKEHE--------KIHTGEKPFECSQCGRAFSQKQYLIKHQNIHSG---KKPFKCNECGKAFSQKENLIIHQRIHTG-EKPYECKGCG--KAFIQKSSLIRHQRSHT-------------GEKPYTCKECGK--------------------------------------------------------AFSGKSNLTEHEKIHIG---------EKPYKCNECGTIFRQKQYLIKHHNIHTG-EKPYECNKCGKAFSRITSLIVHVRIHTGDKPYECKICGKAFCQ-SSSLTVH---------------MRSHTGEKPYGC--NECGKAFSQFSTLALHMRIHTGEKP------YQCSECGKAFSQKSHHIRHQRIHIH--------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N141-1", "uniprot_id": "ZFP82_HUMAN", "id": "Q8N141-1", "name": "Zinc finger protein 82 homolog", "aln": "-------------------------------------------------------------------------------------------------MALRSVMFSDVSIDFSPEEWEYLD--------LEQKDLYRDVMLENYSNLVSLG-CFISKPDVISSLEQGKE----------PWKVVRKGRRQYPDLE--------------------------------------------------TKYETKKLSLENDIYEINLSQWKIMERIE--NHGLKG--------------LILKNDWEST------------------GKIEGQERPQ-------------------------------------------EGYFSSVKMPSEKVSSYQKR---------------TSVTPHQ-----------------------------------------------------------------------------------------------------RLHFVDKPYECKECGKAFRVRQQLTFHHR-IHTGEKPYECKECGMAFRQTAHLTRHQRLHSGEKLYECKECGEAFICGADLRVHQKMHIGEKP----------------------------------------------------------------------------------------------------------------YECKECGKAFRVRGQLTLHQ--------RIHTGEKPYVCKECGKAFRQYAHLTRHQKLNSA---DRLYECKECGKAFLCGSGLRVHHKLHTG-EKPYECKECG--KAFRVRQQLTLHQRIHT-------------GEKPYECKECGK--------------------------------------------------------TFSRGYHLILHHRIHTG---------EKPYECKECWKAFSRYSQLISHQSIHIG-VKPYDCKECGKAFRLLSQLTQHQSIHIGEKPYKCKECGKAFRL-RQKLTLH---------------QSIHTGEKPFEC--KECRKAFRLNSSLIQHLRIHSGEKP------YECKECKKAFRQHSHLTHHLKIHNVKI------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JT46-1", "uniprot_id": "A0A0G2JT46_RAT", "id": "A0A0G2JT46-1", "name": "Zinc finger protein 545", "aln": "-------------------------------------------------------------------------------------------------MARVSVMFSDVSVVFSKEEWDCLD--------LDQRTLYRDVMMENYHNVLSLAGCFISKPDVISLLEQGKE----------PWK-----RRRCPDSG--------------------------------------------------VKDETHQLFSENGVYAVSLSQWKIMERIG--NSGLKS--------------LLLKHEWASR------------------RRQERQEGSR-------------------------------------------EGYLSQVKHTSERVSSSEK----------------CTLTTRQ-----------------------------------------------------------------------------------------------------RIPSVEKPYECDACGKAFRVRQQLTFHHR-IHTGEKPYECKECGMAFRQTAHLTRHQRLHSGEKLYECKECGQAFIYGPDLRAHQKLHTGEKP----------------------------------------------------------------------------------------------------------------YACKECGKAFRVRGQLTLHQ--------RIHTGEKPYVCKECGKAFRQYAHLTRHQKLNVA---DRLYACKECGKDFLCGSGLRVHHKLHTG-EKPYECKDCG--KAFRVRQQLTLHQRIHT-------------GEKPYECNECGK--------------------------------------------------------TFSRGYHLILHHRIHTG---------EKPYECKECWKAFSRYSQLISHQSIHIG-VKPYDCKECGKAFRLLSQLTQHQSIHAGEKPYTCKECGKSFRL-RQKLTLH---------------QSIHTGEKPFEC--KECRKAFRLNSSLIQHLRIHSGEKP------YECKECKKAFRQHSHLTHHLKVHSVQV------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UJU3-1", "uniprot_id": "ZN112_HUMAN", "id": "Q9UJU3-1", "name": "Zinc finger protein 112", "aln": "-----------------------------------------------------------------------------------------------MTKFQEMVTFKDVAVVFTEEELGLLD--------SVQRKLYRDVMLENFRNLLLVA-HQPFKPDLISQLEREEKLLMVETETPRDGCSGRKNQQKMESIQEVTVSYFSPKELSSRQTWQQSAGG-------LIRCQDFLKVFQGKNSQLQEQGNSLGQVWAGIPVQISEDKNYIFTHIGNGSNYIKSQGYPSWRAHHSWRKMYLKESHNYQCRCQQISMKNHFCKCDSVSWLSHHNDKLEVHRKENYS---CHDCGEDIMKVSLLNQESIQTEEKPYPCTGYRKAFSNDSSSEVHQQFHLEGKPYTYSSCGKGCNYSSLLHIHQNIER------------------------------------------------------------------------------------EDDIENSHLKSYQRVHTEEKPCKCGEYGENFNHCSPLNTYEL-IHTGEMSYRHNIYEKAFSHSLDLNSIFRVHTRDEPHEYEENENVFNQSSCLQVHQKIHTEEKLYTDIEYGKSFICSSNLDIQHRVHMEENSYNSEECGNGFSLASHFQDLQIVHTKEQPYKRYVCSNSFSHNLYLQGHPKIHIGEKPRKEHGNG--FNWSSKLKDHQRVHTGQKPYKCNICGKGFNHRSVLNVHQ--------RVHTGEKPYKCEECDKGFSRSSYLQAHQRVHTG---EKPYKCEECGKGFSRNSYLQGHQRVHTG-EKPYKCEECG--KGFSRSSHLQGHQRVHT-------------GEKPFKCEECGKGFSWSFNLQIHQRVHTGEKPYKCEECGKGFSKASTLLAHQRVHTGEKPYQCDECGKSFSQRSYLQSHQSVHSG---------ERPYICEVCGKGFSQRAYLQGHQRVHTR-VKPYKCEMCGKGFSQSSRLEAHRRVHTGGKPYKCEVCTKGFSE-SSRLQAH---------------QRVHVEGRPYKC--EQCGKGFSGYSSLQAHHRVHTGEKP------YKCEVCGKGFSQRSNLQAHQRVHTGEKPYKCDACGKGFRWSSGLLIHQRVHSSDKFYKSEDYGKDYPSSENLHRNEDSVLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VG72-1", "uniprot_id": "Q9VG72_DROME", "id": "Q9VG72-1", "name": "Zinc finger protein 865", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MDLANVDQRPVK-DEPPQ-----------------------------------EDTFEEELIFIS---------------------------------NSDFEELESEIKIENFCSYGKDLEPVKGVPSKLKTCKSKIAKKRP----------------------------------------------------------------------------------LRKQTDTFKCTQCQKTFTRKENLESHLRLHAEERPFECSHCSKSFGRRTHYKRHLLKHE------------------------------------------------------------------------------------------------------KRPHKCSHCSKTFTQNSSLKQHLH-EHTGERPFKCTQCSTSFARKSHLQVHLRTHSEERPFECTHCEKAFKNNSHLQEHLRTHQEARP----------------------------------------------------------------------------------------------------------------FKCSHCSKSFKLRSILQKHL--------LTH-AERSFKCTQCPKTFLQNDSLQIHLRVHAG---EDPFKCPHCSETFARNSRLQLHLLEHAG-KEPLKCSQCS--ATFAMRSLYRVHVRLHT-------------RERQYKCAECSK--------------------------------------------------------SFFKKSHLVEHQQVHTG---------ERPFKCTHCFKDFKCRTHLRVHMLDHIG-EKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTT-SSTLHMH---------------LRTHTGELPFKC--SHCSKLFARSAEHQEHLRTHTGEKP------YKCSHCSTRYTQKSSLGRHLRRTLCGTKSD---------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8N393-1", "uniprot_id": "ZN786_HUMAN", "id": "Q8N393-1", "name": "Zinc finger protein 786", "aln": "----------------------------------------------------------------------------------------------MAEPPRLPLTFEDVAIYFSEQEWQDLE--------AWQKELYKHVMRSNYETLVSLD-DGLPKPELISWIEHGGEPFRKWRESQKSGNIICSSVDMHFDPGFEEQLFWGSQQ-----------------------------AMNSGKTKSHFQLDPESQCSFGSFVSFRPDQGITLGSPQRHDARAPPPLACGPSESTLKEGIPGPRNLDLPGLWDVPAWESTQHPWPVCGESCWENNHLVMHQRGHSKDRTRRAWEKFNKRAETQMPWSSPRVQRHFRCGVCGKSFRRKLCLLRHLAAHTGRGPFRNADGEMCFRHELTHPSHRLPQQGEKPAQCTPCGKRSLPVDSTQARRCQHSREGPASWREGRGASSSVHSGQKPGSRLPQEGNSHQEGDTEALQHGAEGPCSCSECGERSPMSARLASPCRAHTGEKPFQCAHCTKRFRLRRLLQVHQH-AHGGERPFSCRKCGKGFAKQCKLTEHIRVHSGEKPFRCAKCGRNFRQRGQLLRHQRLHTDEKP----------------------------------------------------------------------------------------------------------------FQCPECGLSFRLESMLRAHR--------LRHGGERPFSCSECGRGFTHQCKLREHLRVHSG---ERPFQCLKCDKRFRLKGILKAHQHTHSK-ERPFSCGECG--KGFTRQSKLTEHLRVHS-------------GERPFQCPECNR--------------------------------------------------------SFRLKGQLLSHQRLHTG---------ERPFQCPECDKRYRVKADMKAHQLLHSG-EMPFSC-ECGKGFVKHSKLIEHIRTHTGEKPFQCPKCDKSFRL-KAQLLSH---------------QGLHTGERPFHC--PECDKNFRERGHMLRHQRIHRPERP------FACGDCGKGFIYKSKLAEHIRVHTKSCPAPNELDIKKRLSQLFAMIEADWS------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3U288-1", "uniprot_id": "ZN710_MOUSE", "id": "Q3U288-1", "name": "Zinc finger protein 710", "aln": "-----------------------------------------------------------------------------------------------MEGFMDSGTQTDAVVVLSLAQAAVLG--------LVSENELFGATISAEAFYPDLGPELTGTAMGEPGPPGPDIYQLACNGRALEEPPEEEVLEVEAAFEKHTR---RKTRPPVR--------------------------LVPKVKFEKAEEEEEQEVYEVS--VPGDDK---DPGPAEAPAEVASSGCEALVQSSAVKMIDLS--AFSRKPRTLRHLPRTPRPELDMAPFDPPFPDPARDG-FPEPSMALPGPETLPTECSFEPPHLAPLSNPEPPNMTSTTELVKPEQGFVWQESSEFEADTAGSTVERHKKAQLDRLDINVQIDDS--------------------------------------------------------------------------------------------YLVEAGDRQKRWQCRMCEKSYTSKYNLVTHIL-GHNGIKPHSCPHCSKLFKQPSHLQTHLLTHQGTRPHKCQVCHKAFTQTSHLKRHMLLHSEVKP----------------------------------------------------------------------------------------------------------------YSCHFCGRGFAYPSELKAHE--------VKHESGRCHVCVECGLDFSTLTQLKRHLASHQG---PTLYQCLECDKSFHYRSQLQNHMLKHQN-VRPFVCTECG--MEFSQIHHLKQHSLTHK-------------GVKEFKCEVCGR--------------------------------------------------------EFTLQANMKRHMLIHTS---------VRPYQCHICFKTFVQKQTLKTHMIVHSP-VKPFKCKVCGKSFNRMYNLLGHMHLHAGSKPFKCPYCSSKFNL-KGNLSRH---------------MKVKHGVMDISL--DSQDPMMELAGPDPSELDNHQEMED------FEENAYTYSSVDSSAEASTLTEQAMKEMAYYNVL-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G6X3-1", "uniprot_id": "A0A8I6G6X3_RAT", "id": "A0A8I6G6X3-1", "name": "Zinc finger protein 710", "aln": "-----------------------------------------------------------------------------------------------MEGFMDSGTQTDAVVVLSLAQAAVLG--------LVSENELFGATISAEAFYPDLGPELSGTAMGEPGPPGPDIYQLACNGQALEEPPEEEVLEVEAAFEKHTR---RKTRPPVR--------------------------LVPKVKFEKAEDEEEQEVYEVS--VPGDDK---DPGPAEAPEEAASGGCEALVQSSAVKMIDLS--AFSRKPRTLRHLPRTPRPELDTAPFDPPFPDPARDG-FLEPSMALPGSETLPTECSFEPPHLAPLSNPEPPNMTS-TELVKPEQGFVWQESSEFEADTAGSTVERHKKAQLDRLDINVQIDDS--------------------------------------------------------------------------------------------YLVEAGDRQKRWQCRMCEKSYTSKYNLVTHIL-GHNGIKPHSCPHCSKLFKQPSHLQTHLLTHQGTRPHKCQVCHKAFTQTSHLKRHMLLHSEVKP----------------------------------------------------------------------------------------------------------------YSCHFCGRGFAYPSELKAHE--------VKHESGRCHVCVECGLDFSTLTQLKRHLASHQG---PTLYQCLECDKSFHYRSQLQNHMLKHQN-VRPFVCTECG--MEFSQIHHLKQHSLTHK-------------GVKEFKCEVCGR--------------------------------------------------------EFTLQANMKRHMLIHTS---------VRPYQCHICFKTFVQKQTLKTHMIVHSP-VKPFKCKVCGKSFNRMYNLLGHMHLHAGSKPFKCPYCSSKFNL-KGNLSRH---------------MKVKHGVMDISL--DSQDPMMELAGPDPSELDNHQEMED------FEENAYTYSSVDGSTEASALTEQAMKEMAYYNVL-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N1W2-1", "uniprot_id": "ZN710_HUMAN", "id": "Q8N1W2-1", "name": "Zinc finger protein 710", "aln": "-----------------------------------------------------------------------------------------------MEGFMDSGTQTDAVVVLSLAQAAVLG--------LVSENELFGATISAEAFYPDLGPELSGAAMGEPEPPGPDVYQLACNGRALEEPAEEEVLEVEAACEKHTR---RKTRPPVR--------------------------LVPKVKFEKVE-EEEQEVYEVS--VPGDDK---DAGPAEAPAEAASGGCDALVQSSAVKMIDLS--AFSRKPRTLRHLPRTPRPELNVAPYDPHFPAPARDG-FPEPSMALPGPEALPTECGFEPPHLAPLSDPEAPSMES-PEPVKPEQGFVWQEASEFEADTAGSTVERHKKAQLDRLDINVQIDDS--------------------------------------------------------------------------------------------YLVEAGDRQKRWQCRMCEKSYTSKYNLVTHIL-GHNGIKPHSCPHCSKLFKQPSHLQTHLLTHQGTRPHKCQVCHKAFTQTSHLKRHMLLHSEVKP----------------------------------------------------------------------------------------------------------------YSCHFCGRGFAYPSELKAHE--------VKHESGRCHVCVECGLDFSTLTQLKRHLASHQG---PTLYQCLECDKSFHYRSQLQNHMLKHQN-VRPFVCTECG--MEFSQIHHLKQHSLTHK-------------GVKEFKCEVCGR--------------------------------------------------------EFTLQANMKRHMLIHTS---------VRPYQCHICFKTFVQKQTLKTHMIVHSP-VKPFKCKVCGKSFNRMYNLLGHMHLHAGSKPFKCPYCSSKFNL-KGNLSRH---------------MKVKHGVMDIGL--DSQDPMMELTGTDPSELDGQQEMED------FEENAYSYASVDSSAEASVLTEQAMKEMAYYNVL-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q8N3-1", "uniprot_id": "A0A8M9Q8N3_DANRE", "id": "A0A8M9Q8N3-1", "name": "Zinc finger protein 710", "aln": "------------------------------------------------------------------MRSLKHLKPQTKKNVEEKTQRLVRCYSEAMHQQMDAGTQTDPVVVLSLAQAAVLG--------LISQNEVFGATIAPNGFYTGD-PKESPAPPGERMDYEYADQLIGANGDYLGENLGEDGHMHSSCAERRWQGQPENTKPPVGH-----------------------QDMALHVKGESVTPGLPSCTHMMNNMVPREGMQMVDPTSYRVLPKSQSSNCSTTCVRDPKSTLSPPDPHLHSHSHGHNHAPHEVPTRNRGHTHEKGVDEVAEDRDNGRNGMGKAGNGEEQISSYFQANEVG----YEGGEMEGVGDFDENNDGMFWTEPVEGEAPRG---------RRIDRLDINIQINES--------------------------------------------------------------------------------------------YCVDVGEGLKRWKCRMCEKSYTSKYNLVTHIL-GHNGIKPHACPHCGKLFKQPSHLQTHLLTHQGTRPHKCTVCKKGFTQTSHLKRHMLQHTDVKP----------------------------------------------------------------------------------------------------------------YSCRFCRRGFAYPSELRAHE--------VKHERGRCHVCSQCGMEFPTYAHLKRHQVSHQG---PSTFQCSQCNKSFAYRSQLQNHLLKHQT-QRSFSCSQCG--LQFLQLHQLRQHSLTHKTNKPQ---TRATKGTKGFKCDVCAR--------------------------------------------------------EFTLSANLKRHMLIHAS---------VRPFQCHVCFKSFVQKQTLKTHMIVHLP-VKPFKCKVCGKSFNRMYNLLGHMHLHAGSKPFKCAYCSSKFNL-KGNLSRH---------------MKVKHG-MDVSP--DGQD------GPTDMEPHEDYEDEN------FNFTAPENMENNDAPNLTKLSEVAIQELDYYNFGKDVGNYSTA--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P39933-1", "uniprot_id": "TF3A_YEAST", "id": "P39933-1", "name": "Transcription factor IIIA", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGEVLNNEGMPLAELKQETIPISRSESSESLNSLTSTRSSS-----------------------------------------------------------------------------------------------------SNRPKTYFCDYDGCDKAFTRPSILTEHQLSVHQGLRAFQCDKCAKSFVKKSHLERHLYTHSDTKPFQCSYCGKGVTTRQQLKRHEVTHTKSFI----------------------------------------------------------------------------------------------------------------CPEEGCNLRFYKHPQLRAHI--------LSVHLHK-LTCPHCNKSFQRPYRLRNHISKHHDPEVENPYQCTFAGCCKEFRIWSQLQSHIKND-HPKLKCPICS--KPCVGENGLQMHMIIHDDS----------LVTKNWKCHICPD-------------------------------------------------------MSFSRKHDLLTHYGSIHT---------EEDIPLELKYKISDIQQLVQDHG-VQLG-NSKHSNEQDEEKISNRLRKRRKLTENNNVEFLQNEVDLEKRLE-SGENGLN---------------LLLNTVGRKYRCFYNNCSRTFKTKEKYEKHIDKHKVHEL------KLKILQEKEENKTLVDQNHKEPFIIQKETQSAGDK----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "E1JII8-1", "uniprot_id": "E1JII8_DROME", "id": "E1JII8-1", "name": "Transcription factor Ouib", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRILNCRICSRSDAPIDLFGPGNG--------HLVRQIHSITGVELSCKKEISGQMCTTCLDNLQAAIKFRQRCIIAEKQNLERIECD------------------------------------------------------------------------------------------------------------------SKDCSTDPIIYEDIDDNQ--------IESELDESILCPEVKDLPMP------------------------SAEKVSAPTSLNHQKSIGGG-TGPYVCPDCG--RIINNKSNFQEHTLRHT-------------GIKNFHCVFLNCER------------------------------------------------------SFATRKELTSHTRIHTG---------EQPYVCVYCPRRFSSSGARQEHHRRHRN-ERRYECDTCKKSFVSSGCLRKHKMIHVDARNHYCYVCQKHFKR-ISHLMTH---------------LSSNIHKRKEEK---------------LTELAIEQ-------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q802Y8-1", "uniprot_id": "ZB16A_DANRE", "id": "Q802Y8-1", "name": "Zinc finger and BTB domain-containing protein 16-A", "aln": "----------------------------------------------------------------------------------------------------MDLTKMGMIQLQNPNHPNALL--------HKANQMRLAGTLCDVVIMVDSQEFHAHRTVLACTSKMFEILFHRNSQHYTLDFLSPKTFQQILEYAYTAT-------------------------------------LQAKVEDLDDLLYAAEILEIEYLEEQCLKILETIQSSDENDTEVNMNDGGTEDDEERKGRHGRNLVGSKKHSTEESGYVSAAQQALALPGMVDQSPSVSTSFGLSTMSPTKAAVDSLMSIGQSLLQSTMHPGVGAEQPLHGNSHPMMGEIKTEMMQVDESGEHESPKAMESIASSNGERSGEPDKNRDG-----------------------------------------------------------------------------------------------PGTPTRSSVITSARELHYVRDEGLGDQQAEVSQMGLEAMAGMTEKHLASLYGIPSNHKNEAMLSMPASMASSLHMSPALAMSMDFSAYGGLLP-----------------------------------------------------------------------------------------------------------------QSFIQREFFSKLGELAAGI--------KPDGRSLNERCNVCGAELPDNEAIEQHRKLHSG---MKTYGCELCGKRFLDSLRLRMHLLSHSAGEKAIVCDQCG--AQFQKEDALEAHRQIHTG------------SDMAIFCLLCGK--------------------------------------------------------RFQTQTALQQHMEVHAG---------VRSYICSECNRTFPSHTALKRHLRSHTAGDHPFECEFCGSCFRDESTLKGHKRIHTGEKPYECNGCGKKFSL-KHQLETH---------------YRVHTGEKPFEC--KLCHQRSRDYSAMIKHLRTHNGASP------YQCTICLEYCPSLSAMQKHMKGHKPEDIPPDWRIEKTYLYLCYV-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7ZVR6-1", "uniprot_id": "MYNN_DANRE", "id": "Q7ZVR6-1", "name": "Myoneurin", "aln": "----------------------------------------------------------------------------------MPHITHSEFLLEQLKRQRERSFLCDCTVSIGQAQYRAHHNVLAAFSEYFSTQSVDAGREDPTITLDPESVSSAIFEKLLTYIYTGDLNMDREEIESVQKAASYLGMPEVVARCTLSQDNIKNVGSPMRQAEYEDPRSP------LSPDDYEPLEPISEVEERELLREDRAGDDLVSMDEAQSSSEQTPQRVGKRGRKPKTRLYEDEFEVETISAQRGRGRGRGRPRGRPRVRPLSSDSTDQSPAHQAMSPNGSSTSRGSGRPRGRPRVRPLSTANEDPRNVEDDPAANKDQEVEKGNEEQKKETGEKDDGKNDTDNPEEVTAFKRGRGRPRIKPVSTEDQTTN-----------------------------------------------------------------------------------------SENVTTNAEDGSEPAKTKDSEGTGRKRGRPRSKPVSSEDPESVISVEISGEEAGEETSQDAEKHTEEGTEDSESNPGNSVRISKRKRILSRKLKESQAGDEEEEEEEEMDDEFENDNEDWAGEEE-----------------------------------------------------------------------------VKPVQDKHRPICNICGNLFSEMSSLRRHM--------RIHKGLKPYQCTLCTRSFRQGNQLKTHMRIHTG---EKPFTCTSCDSRFAQKCQLVYHCRMHHGEEKPYKCEFCG--AAFATSSNLKIHIRKHS-------------GEKPYECGECGK--------------------------------------------------------RFTQASTLMYHKRRHTG---------EKPYICDTCGMAFAVSSSLIAHNRKHTG-VTPYICLDCGKPCLTAGELRKHMDVHNDIYSLKKHSILKHNVVPELETTQT---------------SKTDPTQCPLNIPIDHQGLIARVRSALVDSQDHEIQMEPPLPILPPETSLTIQQSAEPQMIIQHADGSEPSMIFQHAEASEAPMLIQHGEPGEQVSYVVEQYEIPATAEMEHTQIVIVQTID----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7Z152-1", "uniprot_id": "B7Z152_DROME", "id": "B7Z152-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFTTFTDLARLCRICLRHLRDRDTHCPDPRLIAILQKLLDIDILKQPHG---------------------------------------------------------------------------------FPTEICNLCHNAVVYFDELRQVARESSQKLIGWQPVDIAVDRVKEEPPDEGLKEN-----------------------------------------------------------------------------------------------------HEENEHELEEEHEKQADGQQVDLSKKQEDQKKILDDREDEEYPDEYENSQQQLSQGTGSKRRAGLACDQCGKQVYKLPYLEAHIRSVHQGYS--------------------------------------------------------------------------------------------------------------KPFLCRSCDKSFTRYEQLRSHMRNAHPQLEQLQQELRDLICELCNRQYSTKNALGEHLKRHAQ---RKEHVCEHCGVAKVTRTELLTHLRTHNPTWERFKCEQCP--QLFRHKSAISRHVRVVHE------------GQRRFQCGHCEK--------------------------------------------------------KFGTHASQVRHERLHTESTGSGEAAEEWPFACIHCQKPCVSRQTLELHLRRHRA-RKTHRKRREHSRESQEQEQEHDRDQEQGAREAQQDQLRKGEKLRQRDLSRE---------------SHRNEVTMQTSQRPNECQQGQESYDPEPDPLEASQCKLE------QEDALDPEWQHKIEQDAESQDSARLEGHFHDYKPIPSKAL-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JQX6-1", "uniprot_id": "A8JQX6_DROME", "id": "A8JQX6-1", "name": "Transcription factor Ouib", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKEFCRTCGKTVVADECLQIFTPAGRKLLQCVRSITNCWLQN----------------------------------------------------------------------------------------------------------VQDLPNHICTDCQVLLSQVQKFRRRCAKIEKYFARRRRRMNLGEAPAAMEQLRVQQAAAPDPLGIDELMSASDIKIEPIQLQMEEDPQ--------------------------------------------------------------------------------------------------------------APYPENQLEQALSYGNAPGEDILP----LPEDYGEAQTEVATTTNEPAQRRSKNTAKIKSKKH---TMRVGRKLIHVKVIDDKQPKRIVDRNGPSAKPCICEHCG--RQFKDTSNLHVHLLRHT-------------GTKPFECDQCHQ--------------------------------------------------------KCYTLHLLRRHQLKHTEG----------PYACTFCGLEYSTNSSRVRHEREACK--------------KGRAPQSKWEIIKKGERTFHCEVCDLWFLR-AGNFTQH---------------INSSSHIENERR-----------KKRKSNPTAINS-------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15619-1", "uniprot_id": "SRYC_DROME", "id": "P15619-1", "name": "Serendipity locus protein H-1", "aln": "----------------------------------------------------------------------------MEGGKGEGKRMKEEAPSKKLPPKIYGGDAGTPTKAAHDEILSSLLRINNFDSISSIKDESLDIDLSACVTISSASLVNGNSLSSTDFWRVLDESAQNNTELNLSSDVCRDDLAATSSSTVPSTLTSDNHSSSEFSVTFLRPEPP------NAFTNSPFKKTSSSGTSTPVKLSPEQLHQQHQLQMPQSQLLQRKPKLPAATAVRLKVFKEEPPEEKHPPEQVVTKVEVCESELLPPSFTIFQQAKSAESVADAASMPPPAASETKPLEVDPAPLHKCLDCNGLLLETPDEVAKHEAAAHRLRLTYRCSECQREFELLAGLKKHLKTHRTEGRKDTWKKCPDCGKCLKLG-----------------------------------------------------------------------------------------SMWMHRKIHSDNKKYQCDICGQKFVQKINLTHHAR-IHSSEKPYECPECQKRFQERSHLQRHQKYHAQTRSYRCEKCGKMYKTERCLKVHNLVHLEQRP----------------------------------------------------------------------------------------------------------------FACTVCDKSFISNSKLKQHS--------NIHTGMRPFKCNYCPRDFTNFPNWLKHTRRRHKVDHKTGEHLENIPSYCSKKSTTNKAQKAAAAAAAAAAASSAVNPNELSASSELKAKANLTSTAAPA---P-AKQARKKKQPQQATLAALGITLPAGTALQQVHPVPLAQQHQQELTTVLVPLAPPAPKQTKAKRERKQLAPKQLQQKPQLLQQGQPQQSSLEPIPAVPQIKKEPVQTQGPFLDLHGLSLTSAEELIMEQALEMEECGLYDAPNANTEMGTSDNAISDSAAALHFQIKNELPDELLPDDDFL--------PCKPSDRLPCPSLESSPFSSPASMELTAVSCASSVAISTNALPVRSGNYYLPAFTLNAHGKLSSTGNGVQSVTTSLAQTPSVSMVNVPLLVRSNQMLPSVDTLLFTNQTGGSRFFAGKSATAATPHLT--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8I5ZTI4-1", "uniprot_id": "A0A8I5ZTI4_RAT", "id": "A0A8I5ZTI4-1", "name": "", "aln": "---------------------------------------------------------------------------MIGLMCFDVGCRVSYGRAGNLLSRDMTVTFEDVHVNFTQEEWALLDPFQKKLYKDVMLETYRNLNAIGFNWEEQNIEEHCQRSRRQKRYFLYASSYKYASEEILMCAESLKVKQQCMKEVRVQRFPPNILTVENPLLYMLTVILKGMKGSIQKRSPLKLFSVLKPLLLTQVSKYIKEHKLDRNLMDVVNVVKFFQITVNLKSMKVFILKRNPTSIMNVIKPIHDPVASRCIKEFILERNPTNVMNVIKPFQTTVASRSIKEFTLERNTTNVMNVIKHFQYTVASRRIKEFTLDRNPTNVMNVIKPFHDPVDSSSINIFTLERNPTSVMNVIKPFHNTIAYGSIKEIILER--------------------------------------------------------------------------------------------NPTNVMNVIKPFQTTVASSRIKEITTEKNPTN-VMNVIKPFHDPVTSRHIKVFTLERNPTNVMNVIKPFHDPVASRSIKEFTLERNPTNVMNVIKPFQTTVASSRIKEFTLERNPTNVMNVIKPFQTTVASSRIKEFTLERNPTNVVNVIKPFQKPVASRSIKEFTLERNPTNVMNVIKPFQYTVTSGSIKEFTLERNPTNVMNVIKHFHDTVASRHIKEFTLERNPT--------NVMNVIKPFHDLVASRSIKEFTLLRNPTNVMNVIKHFQYTVASRRIKEFTLERNPTNVMNVIKPFHDPVDSSSINMFTLERNPTNVMNVIKPFRNTVASRCIKEFTLERNPTNVMNVVKPFQDTVTSRSIKEFTLERNPTNVMNVIKPFQKSVASRSIKEFTLERNPTNVMNVIKPFQYTVTSGSIKEFTLERNPTNVMNVIKPFQTTVASRHIKEFT-LERNPTNVMNVIKPFQDPVASRHIKEFTLERNPTNVMNVIKPFHDPVASRSIKEFTLERNPTNVMNVIKPFHDAVASRSIKEFTLERNPTNAMNVIKPFHDPVDSSTIKLHTGQKP------YKCNECFEAFSEHSSLQMQKRIHTGEKPYKCNECDKAFSYHTSLQNHSRIHTIAKP-------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ", "identical_positions": 0, "similar_positions": 1, "identity": "0.0%" }, { "cls_id": "homologset.agr.SGD:S000006391", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88828-1", "uniprot_id": "RPAB2_RAT", "id": "O88828-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC2", "aln": "MSDNE----------DNFDGDDFDDVEEDEGLDDLENAEEEGQENVEILP---SGERP------------------QANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLLIAMKELKARKIPIIIRRYLPDGSYEDWGVDELIISD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61219-1", "uniprot_id": "RPAB2_MOUSE", "id": "P61219-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC2", "aln": "MSDNE----------DNFDGDDFDDVEEDEGLDDLENAEEEGQENVEILP---SGERP------------------QANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLLIAMKELKARKIPIIIRRYLPDGSYEDWGVDELIISD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61218-1", "uniprot_id": "RPAB2_HUMAN", "id": "P61218-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC2", "aln": "MSDNE----------DNFDGDDFDDVEEDEGLDDLENAEEEGQENVEILP---SGERP------------------QANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLLIAMKELKARKIPIIIRRYLPDGSYEDWGVDELIITD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24320-1", "uniprot_id": "RPAB2_DROME", "id": "Q24320-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC2", "aln": "MDDADYDN-------DDVGGDDFDDVDED--VDEDINQEEE-ADNIEIIAPGGAGGGG------------------VPKSKRITTKYMTKYERARVLGTRALQIAMCAPIMVELDGETDPLQIAMKELKQKKIPIIIRRYLPDHSYEDWSIDELIMVDN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20435-1", "uniprot_id": "RPAB2_YEAST", "id": "P20435-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC2", "aln": "MSDYEEAFNDGNENFEDFDVEHFSDEETYEEKPQFKDGETTDANGKTIVT---GGNGPEDFQQHEQIRRKTLKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.* : ::.. :.*.* : : : * :. *:. .* .:.:* ** *********:********:* **::*:*:****** ****** :***::******* *:***.::***: ", "identical_positions": 61, "similar_positions": 35, "identity": "38.36%" }, { "cls_id": "homologset.agr.SGD:S000006392", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QVP4-1", "uniprot_id": "MLRA_MOUSE", "id": "Q9QVP4-1", "name": "Myosin regulatory light chain 2, atrial isoform", "aln": "MASRKAGTRGK-------------------------------------------AAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKSDLKETYSQLGRVSVPEEELDAMLQE--------GKGPINFTVFLTLFGEKLNGT---DPEEAILSAFRMFDPSGQGVVNKEEFKQLLMTQADKFSPAEVEQLFALTPMDLAGNIDYKSLCYIIT-HGD-EKEE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M7K3-1", "uniprot_id": "F1M7K3_RAT", "id": "F1M7K3-1", "name": "", "aln": "MASRKAGTRGK-------------------------------------------AAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKSDLKETYSQLGRVSVPEEELDAMLQE--------GKGPINFTVFLTLFGEKLNGT---DPEEAILSAFRMFDPSGQGVVNKEEFKQLLMTQADKFSPAEVEQLFALTPMDLTGNIDYKSLCYIIT-HGD-EKEE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01449-1", "uniprot_id": "MLRA_HUMAN", "id": "Q01449-1", "name": "Myosin regulatory light chain 2, atrial isoform", "aln": "MASRKAGTRGK-------------------------------------------VAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELDAMLQE--------GKGPINFTVFLTLFGEKLNGT---DPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIIT-HGD-EKEE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02045-1", "uniprot_id": "MYL5_HUMAN", "id": "Q02045-1", "name": "Myosin light chain 5", "aln": "MASRKTKKK---------------------------------------------EGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDTYASLGKTNVKDDELDAMLKE--------ASGPINFTMFLNLFGEKLSGT---DAEETILNAFKMLDPDGKGKINKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVIT-HGE-EKEE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10916-1", "uniprot_id": "MLRV_HUMAN", "id": "P10916-1", "name": "Myosin regulatory light chain 2, ventricular/cardiac muscle isoform", "aln": "MAPKKAKKR---------------------------------------------AGG------ANSNVFSMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMIKE--------APGPINFTVFLTMFGEKLKGA---DPEETILNAFKVFDPEGKGVLKADYVREMLTTQAERFSKEEVDQMFAAFPPDVTGNLDYKNLVHIIT-HGE-EKD---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O14950-1", "uniprot_id": "ML12B_HUMAN", "id": "O14950-1", "name": "Myosin regulatory light chain 12B", "aln": "MSSKK--AKT--------------------------------------------KTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGK-NPTDAYLDAMMNE--------APGPINFTMFLTMFGEKLNGT---DPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILK-HGAKDKDD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19105-1", "uniprot_id": "ML12A_HUMAN", "id": "P19105-1", "name": "Myosin regulatory light chain 12A", "aln": "MSSKR--TKT--------------------------------------------KT-KKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGK-NPTDEYLDAMMNE--------APGPINFTMFLTMFGEKLNGT---DPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILK-HGAKDKDD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P24844-1", "uniprot_id": "MYL9_HUMAN", "id": "P24844-1", "name": "Myosin regulatory light polypeptide 9", "aln": "MSSKR--AKA--------------------------------------------KTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGK-NPTDEYLEGMMSE--------APGPINFTMFLTMFGEKLNGT---DPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILK-HGAKDKDD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40423-1", "uniprot_id": "SQH_DROME", "id": "P40423-1", "name": "Myosin regulatory light chain sqh", "aln": "MSSRKTAGRR--------------------------------------------ATTKKRAQRATSNVFAMFDQAQIAEFKEAFNMIDQNRDGFVEKEDLHDMLASLGK-NPTDDYLDGMMNE--------APGPINFTMFLTLFGERLQGT---DPEDVIKNAFGCFDEENMGVLPEDRLRELLTTMGDRFTDEDVDEMYREAPI-KNGLFDYLEFTRILK-HGAKDKDEQ-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P18432-1", "uniprot_id": "MLR_DROME", "id": "P18432-1", "name": "Myosin regulatory light chain 2", "aln": "MADEKKKVKKKKTKEEGGTSETASEAASEAATPAPAATPAPAASATGSKRASGGSRGSRKSKRAGSSVFSVFSQKQIAEFKEAFQLMDADKDGIIGKNDLRAAFDSVGK-IANDKELDAMLGE--------ASGPINFTQLLTLFANRMATSGANDEDEVVIAAFKTFDND--GLIDGDKFREMLMNFGDKFTMKEVDDAYDQMVIDDKNQIDTAALIEMLTGKGEEEEEEAA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06580-1", "uniprot_id": "MLC2_YEAST", "id": "Q06580-1", "name": "Myosin light chain 2", "aln": "------------------------------------------------------------MDHSESLTFNQLTQDYINKLKDAFQMLDEDEDGLISRGDLTKIYATLGK-TLTDEEWSKMVPDNDTSTAEVGEEGVSFPIFLSIMGKNLSQFP---EREELEESLKAIGRGHDLNVPLNEVIDSLKEAGFENPEEEFAKLFKLFTTNQQATEERTFRGKLFL---DSITD---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * .* : * * ::*:** :* :.**:: : ** :*: : . *: : . :.*. :*.::.:.: : : :: :. : : . * . . . :. . : : :: : ", "identical_positions": 17, "similar_positions": 50, "identity": "7.3%" }, { "cls_id": "homologset.agr.SGD:S000006393", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F8VPK0-1", "uniprot_id": "SKI3_MOUSE", "id": "F8VPK0-1", "name": "Superkiller complex protein 3", "aln": "MSSKEVKTALKSARDAIRNKEYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQP---------DQAQGAYKKAAELEPEQLLAWQGLASLYEKCNQVNAKDDLPGVYQKLLDLYESADRQKWCDVCKKLVALYHQEKKHLEVARTWHRLIKTRQEDGADRQELYELWRKLSQLLAENIEDQNNETQQMLLTAFENALDLADNIPSEDHQVLYRNFIQCLSKFPHETTKLKKACEEMIAIYPTVQYPLEVICLYLIDSGSLTSEGHQYCCKLVEMNSKSGPGLIGLGIIALQDKKYEDAVRHLTEGLKESPVCIAGWCHLAEAQVKMHRPKEAILSCNQALKTIDNFGASGGNLHQKNLCLRLKAEALLKLSDGASSEEAVRTLDQVSDVDNTPGLLVLQGLACLNTGAVDKATKIMEDLVTSYPDLAEAHALEGRVHFTKKDYVQAEVSFQRALEKDAEVAEYHYQLGLTYWFMGEETRKDKTKALTHFLKAARLDAHMGKVFCYLGHYYRDVAGDRNRARGCYRKAFELDDNDAESGAAAVDLSLELEDTETALAILTAVTQKASAGAAKWAWLRRGLYHLKAGQHSQAVADLQAALRADPKDCNCWESLGEAYLSRGGYTTALKSFMKASELNPDSTYSVFKVAAIQQILGRYSEAIAQYQLIIKMKEDYVPALKGLGECHLLLGKVALVDFLDGKAVDYVEQALGYFTRALQHRADVSCLWKLVGDACTCLHPVSPSKVHVHVLGALLGQKEGQEVLKKEELLSLGGRCYGRALKLMSTSNTWCDLGINYYRQVQHLAETGSSMSDLTELLEKSLHCLKKAVRLDSNNHLHWNALGVVACYRGVGNYALAQHCFIKSIQAEQINAAAWTNLGVLYLATENIEQAHEAFKMAQSLDPSYLLCWIGQALIAERVGSYDTMDLFRHTTELSMHTEGAIGYAYWVCTTLQDKSNRETELYQYNILEMNAIPAAQGVLCKYVERIQNSASAFTMLGYLNEHLQLKKEAAEAYQRATTLLHSAEDQNTYNVAVRNWGRLLCSIGDYDRAIQAFKSTPLVELEDIIGFALALFMKGLYKESGSAYERALAVCKSEQDKAHILTAMAIVEYKQGKMDAAKSFLFKCSILKEPTAESLQALCALGLAMRDATLSKAALNELLKHIKRRN-DYHSCLLMSAIYALQGHSVAVQRQVAKAVHSNPADPALWSLLSRIVAQYTQRSAKGGAVAGNVAHILDLNHGKKALLYTAVNQLAMGSSTAEDKSNTALKTIQKAAFLSPD-----DPAVWAGLMAACHADDKLALLNNTQPKRVDLYLALRSAVAASLKDKEILQNYNQSLEKWSFSQVVTGLIDTGKTSEAESLCTQSLKSNPDQPAVILLLRQVQCMSLLESQKPLPDAVLEELQKTVMSNSTSVPAWQWLAQVYQSQGMMGAAEMCYRKSLQVASQQGNWSGKLSSLLKLALLALEVCMANVSGDHWSSLVQEATSEALKVCFSPLAVFLQALLQFNRKMGARET-RRLLERIVYQTGYPSSIVSAARWYLLRHLYAKDDP-----ELIDVLVRNAETHGDKRILELNRKLSAQ--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZL50-1", "uniprot_id": "D3ZL50_RAT", "id": "D3ZL50-1", "name": "Superkiller complex protein 3", "aln": "MSSKEVKTALKSARDAIRNKEYKEVLKHCKTVLKQEKDNYNAWVFIGVAAAELGQP---------DQAQGAYKKAAELEPEQLLAWQGLASLYEKCNHINAKDDLPGVYRKLLDLYESVDKQKWCDVCKKLVDLYHQEKKHLEVARTWYRLIKARQEDGADRQELYELWRKLSQLLSEDAEDQNDETQQMLLTAFENALDLADNVPSEDHQVLYRNFIQYLSKFPHEMTRLKKACEGMITMYPAVQYPLEVICLYLIDSGNLTDEGHQYCYKLVEMNSKSGPGLIGLGIRALQDKKYEDAISHLTEGLKESPLCIAGWCHLAEVQVKVHRPKEAILSCNRALKTIDNLGASGGSLHQKNLCLRLKAEALLKLSDCASLEEAVHILDQLSDTDNTPGLLVLQGLACLNTGAIDKATKIMEDLVASYPDLSEAHALEAYVHFTKKDYVQAETSFQRALEKDAEVAEYHYQLGLTYWLMGEETRKDRTKALNHFLKAARLDAHMGKVFCYLGHYYRDVAGDRNRARGCYRKAFELDDSDAESGAAAVDLSVELEDTETALAILTAVTQKASSGAAKWAWLRRGLYYLKAGHHSQAVADLQAALRADPKDCNCWESLGEAYLSRGSYTTALKSFTRASELSPDSTYSVFKVAAIQQILGRYSEAIAQYQLIIKKEEDYVPALKGLGECHLMLGKAALVDFLDGKAVDYVEQALGYFTRALQHRADVSCLWKLMGDACTCLHPVSPAKVNVRVSGALLGQQEGQEVLRKDELLHLGGRCYGRALKLMSTSNTWCDLGINYYRQAQHLAETGSSMNDLTELLEKSLHCLKKAVRLDSNNHLYWNALGVVTCYHGVGNYALAQHCFIKSIQAEQINAAAWTNLGVLYLATENIEQAHEAFQMAQSLDPSYLLCWIGQALIAERIGSYETMDLFRHTTELSMHTEGAIGYAYWVCTTLQDKSNRETELYQYNILQMNAVPAAQGVLCKYVERIQNYAPAFTMLGYLNEHLQLKREAAEAYQRATALLHSAEDQHTYNVTVRNWGRLLCSIGDYDKALQAFKSTPLAELEDIIGFALALFMKGLYKESSTAYERALTVCKSEQDKAHILTAMAVTEYKQGKMDAAKSLLFKCSILKEPTAESLQVLCALGLAMQDATLSKAALNELLKHIKQKN-DYHRYLLTSAIYALQGHSVAVQRQVAKAVHSNPADPALWSLLSRIVAQYTQQNAKGGAVAGSVAHILDSNHGKKALLYTAVNQLAMGGSTAEDKSSTALKTIQKAAFLSPD-----DPAVWAGLMAACHADDKLALVSNTQPKRVDLYLALQSAVSASLKDKENLQNYNLLLEKWSFSQAVTGLIDTGKISEAESLCTKNLKSNPDQPAVILLLRQVQCTSLLASQKPLPDAVLEELQKTVMSNSTSVPAWQWLAQVYQSQGMMSAAEMCYRKSLQVASQQGSWSGKLSSLLKLALLALEVCMANVSGDHWSSLVQEATSEALKVCFSPLAIFLQALLQFNRKMGARET-RRLLERVVYQTGYPNSIVSTARWYLLRHLHAKDDH-----ELIDVLVRNAETHGDKRMLELNRKLSAQ--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PGP7-1", "uniprot_id": "SKI3_HUMAN", "id": "Q6PGP7-1", "name": "Superkiller complex protein 3", "aln": "MSSKEVKTALKSARDAIRNKEYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQP---------DQAQSAYKKAAELEPDQLLAWQGLANLYEKYNHINAKDDLPGVYQKLLDLYESVDKQKWCDVCKKLVDLYYQEKKHLEVARTWHKLIKTRQEQGAENEELHQLWRKLTQFLAESTEDQNNETQQLLFTAFENALGLSDKIPSEDHQVLYRHFIQSLSKFPHESARLKKACEGMINIYPTVQYPLEVLCLHLIESGNLTDEGQQYCCRLVEMDSKSGPGLIGLGIKALQDKKYEDAVRNLTEGLKESPVCTSGWYHLAEAQVKMHRPKEAVLSCSQALKIVDNLGASGNSLYQRNLCLHLKAEALIKLSDYDSSEEAIRTLDQISDADNIPGLLVLKSLAYRNKGSFDEAAKIMEDLLSSYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLTYWFMGEETRKDKTKALTHFLKAARLDTYMGKVFCYLGHYYRDVVGDKNRARGCYRKAFELDDTDAESGAAAVDLSVELEDMEMALAILTTVTQKASAGTAKWAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMMAKAALVDYLDGKAVDYIEKALEYFTCALQHRADVSCLWKLAGDACTCLYAVAPSKVNVHVLGVLLGQKEGKQVLKKNELLHLGGRCYGRALKLMSTSNTWCDLGINYYRQAQHLAETGSNMNDLKELLEKSLHCLKKAVRLDSNNHLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQAHEAFKMAQSLDPSYLMCWIGQALIAEAVGSYDTMDLFRHTTELNMHTEGALGYAYWVCTTLQDKSNRETELYQYNILQMNAIPAAQVILNKYVERIQNYAPAFTMLGYLNEHLQLKKEAANAYQRAILLLQTAEDQDTYNVAIRNYGRLLCSTGEYDKAIQAFKSTPLEVLEDIIGFALALFMKGLYKESSKAYERALSIVESEQDKAHILTALAITEYKQGKTDVAKTLLFKCSILKEPTTESLQALCALGLAMQDATLSKAALNELLKHIKHKDSNYQRCLLTSAIYALQGRSVAVQKQISKAVHSNPGDPALWSLLSRVVAQYAQRNAKGGVVAGNVAHILDSNHGKKALLYTAVNQLAMGSSSAEDEKNTALKTIQKAALLSPG-----DPAIWAGLMAACHADDKLALVNNTQPKRIDLYLALLSAVSASIKDEKFFENYNQSLEKWSLSQAVTGLIDTGRISEAETLCTKNLKSNPDQPAVILLLRQVQCKPLLESQKPLPDAVLEELQKTVMSNSTSVPAWQWLAHVYQSQGMMRAAEMCYRKSLQLASQRGSWSGKLSSLLRLALLALKVCMANISNDHWPSLVQEATTEALKLCFCPLAVLLQALLQFKRKMGARET-RRLLERVVYQPGYPKSIASTARWYLLRHLYAKDDY-----ELIDVLVNNAKTHGDTRALELNQRLSSQ--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17883-1", "uniprot_id": "SKI3_YEAST", "id": "P17883-1", "name": "Superkiller protein 3", "aln": "--MSDIKQLLKEAKQELTNRDYEETIEISEKVLKLDPDNYFAHIFLGKALSSLPASNNVSSNRNLERATNHYVSAAKLVPDNLLAWKGLFLLFRTTEVVP----------------DILSYDEYFDLCGQYADALLKQEQSQVELINDIKLLKKTHP---DCQKAFYQHLKPGSLMAETIGRHLSTPQDALLNLIK---ILSNIETTEIGKTLSQNRLKLKASDPDYQIKLNSFSWEIIKNSEIDQLYNQLVNILADDQKRSEIENQWLEYRIKVLKS------MPLDVKKDFFTKVKEMVEDMVLVNHQSLLAWQKYFEWTDY---------------------EDLDNMDAPLIIKYFKKFPKDPLAMILYSWLSSKLSKYDIKSLESANKPP----------------EGHKKTEKETDIKDVDETNEDEVKDRVEDEVKDRVEDEVKDQ---DEEAKEDEEEDLDDIEIGLLEEEVVTVLTENIVKCKNNILAHRILCQYYLLTKEYEAALPYIKN---GISLIAYNIKD---------LGVHLPLTKREFSLDLATVYTYVDAP-----------------KDHNAALKLYDNILSGDFSNIQAKMGKGIIFIERKNWKDAMTLLTQVHEQSPNNLEVLSELSWSKAHMGYMDEALAGLDTVIKGIKG--MDLRSIDFRALNLWRQAKVYIMKHASINDAKQ------------ENVKCAFKLLIQSIKILDTFAPG---------------------FSTLGDIYCHYYKDHLRAFKCYFKAFDLDAGDYTAAKYITETYASKPNWQAASSIASRLIKGEKAKAELRSNNWPFRVVGIAHLEKQEESDSIEWFQSALRVDPNDVESWVGLGQAYHACGRIEASIKVFDKAIQLRPSHTFAQYFKAISLCDVG--EYLESLDILEKVCQEAATEESFQIGLVEVLMRCS---LDLYSQGFLLKSVSIAKDTIERIKIIISELKCENQQVWIYLSQVLRLFIWIESKVDTLPVESLVSIFENSQFSGSE-------EIDSVDNIKIDTLLDSTTDDNVSIACKFLILASKYSVSDQKFTDIAGTVRASYWYNIGISELTAFITLKEPQYRDAAIFAFKKSIQLQSNTS--ETWIGLGIATMDINFR-VSQHCFIKATALEPKATNTWFNLAMLGLKKKDTEFAQQVLNKLQSLAPQDSSPWLGMALILEE--QGDIIGSSKLFAHSFILSNGRSKAAQFMYAKNVLENHINNGDDERDIETVEKLTTASIALEQFFKKSPDSQFALQCALLTLERLHHYENANELANRLIGILEKKFEKTQDERELFN---FAIIKGQFARIHLGLGNFELSIENADLSQGIISESSDEKSMKTKISNHICLGLSYFFLNDFDQTLNQFQELLSISKDSKHLVVLIAKVLYDVGESDTKEIALQELTEYIATSG------ADLLVTLTIAAMSILDDKREDLSIILEELKALPLSKQIIDKHKDAPYLIEEITKRLYRNDTGKQVWQRSAYFFPNNLKVWERLDKNIQRRIASNGQNKVTAEEMSKLYCESKNLRSIQRGMFLCPWNVTAVKALNECF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::* **.*:: : *::*:*.:: .:.*** : :** * :*:* * :.* . ::* . * .**:* *::****:** *:.. : : : . ::: *:* : . :::: . :*:* : : :: . * .:::* : . .*: *:. :: *:: .:* :.* :: :: :. *. :*:. . :* * ::: : :. *.: :: :.* : *.: .* :: : .:. ::* :. : . :: :::. . * : : * : * . * : : :..:...:: * : * :: . * :: . :: :. ** :: * * ::::: * . .: :: **. . *: : : : . : : : .* : :* * *:::.* :.: : * . * :* : *. * :. .*. *: : * .* .: :. . * ::.* .:. *:. : :. * .*:. : ::: : :* .**:* : :** :. *:.:. * : : * * :. ::: :: :*.* :** :: . * ..:*. . * : : * *: :. . **. . * .::::** :. : . : : :* . . * * .: : : : . * .::: : :. :*..** * : .** : :.*. * .* **: :. :*: :* : :: : :: .: .: : .* * :**. .:* .. * : : : : . : **.: *:* . : : :.: . . .. *. . : *. : :: . .. . : * :: * : * *. *: : * : ** ** :..:. :. .**:* * .: .: : ::* . : : : : : : .*: : * * *.: * :: :: : * . *. :.**. .:.* * : * * * ...:*: . .:* :: .* .* .* : ::* .*:: * * . . : .:.: :: : * .::: ** : * *. :....*: :: : : * * * .*:::*: : .. * :*:* . * : *:. :: : : * :.** :* : : * * : : * : : ::.::: .:* ::: :* .* .: . : *:: ::.: *: .: .. : :. * : * : ", "identical_positions": 205, "similar_positions": 500, "identity": "12.88%" }, { "cls_id": "homologset.agr.SGD:S000006394", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIL3-1", "uniprot_id": "RPC3_RAT", "id": "Q5XIL3-1", "name": "DNA-directed RNA polymerase III subunit RPC3", "aln": "----------------------------------------MTQAEIKLCSLLLQEHFGEIVEKIGVHLIRTGSQPLRVIAHDTK-ASLDQVKKALCVLIHHNLVIYHVHKRG---VVEYEAQCSRVLRMLRYPRYIYTTKTLYGDTGELIVEELLLNGKMTMSAVVKKVADRLTETMEDGKTMDYAEVSNAFVRLADTHFVQRCPLVPDTDSSDPG--PPPPAPNLVINEK---DMYLVPKLSLIGKGKRRRSSDEDAAGEPKAKKPRCT-DNEEPTPDDGIYWQVNLDRFHQHFRDQAIVSAVANRMDQTSSEIVRTMLRMS-EITTPSGAPFTQP---------------------------LSSNEIFRSLPVGYN------------------------------------------------------------------------ISKQVLDQYLTLLADDPLEFIGKAGDSGGGMYVINLHKALASLSTATLESVIQERFGSRCARIFRLVLQKKHLEQKQVEDFAMIPAKEAKDMLYKMLSENFISLQEIPKTP--DHAPSRTFYLYTVNVLSAARMLLHRCYKSIANLIERRQFETKENKRLLEKSQRVEAIMASMQATGAEEVQLQEIEEMITAPERQQLETLKRNVNKLDASEIQVDETIFLLESYIESTMKRQ-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D483-1", "uniprot_id": "RPC3_MOUSE", "id": "Q9D483-1", "name": "DNA-directed RNA polymerase III subunit RPC3", "aln": "----------------------------------------MTQAEIKLCSLLLQEHFGEIVEKIGVHLVRTGSQPLRVIAHDTK-ASLDQVKKALCVLIHHNLVLYHVHKRG---VVEYEAQCSRVLRMLRYPRYIYTTKTLYGDTGELIVEELLLNGKMTMSAVVKKVADRLTETMEDGKTMDYAEVSNAFVRLADTHFVQRCPLVPDTDSSDRG--PPPPAPTLVINEK---DMYLVPKLSLIGKGKRRRSSDEDATGEPKAKKPRYT-DNKEPSPDDGIYWQVNLDRFHQHFRDQAIVSAVANRMDQTSSEIVRTMLRMS-EITTPSSAPYTQP---------------------------LSSNEIFRSLPVGYN------------------------------------------------------------------------ISKQVLDQYLTLLADDPLEFIGKSGDSGGGMFVINLHKALASLATATLESVIQERFGSRCARIFRLVLQKKHLEQKQVEDFAMIPAKEAKDMLYKMLSENFILLQEIPKTP--DHAPSRTFYLYTVNVLSAARMLLHRCYKSIANLIERRQFETKENKRLLEKSQRVEAIMASMQATGAEEVQLQEIEEMITAPERQQLETLKRNVNKLDASEIQVDETIFLLESYIESTMKRQ-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BUI4-1", "uniprot_id": "RPC3_HUMAN", "id": "Q9BUI4-1", "name": "DNA-directed RNA polymerase III subunit RPC3", "aln": "----------------------------------------MTQAEIKLCSLLLQEHFGEIVEKIGVHLIRTGSQPLRVIAHDTG-TSLDQVKKALCVLVQHNLVSYQVHKRG---VVEYEAQCSRVLRMLRYPRYIYTTKTLYSDTGELIVEELLLNGKLTMSAVVKKVADRLTETMEDGKTMDYAEVSNTFVRLADTHFVQRCPSVPTTENSDPG--PPPPAPTLVINEK---DMYLVPKLSLIGKGKRRRSSDEDAAGEPKAKRPKYTTDNKEPIPDDGIYWQANLDRFHQHFRDQAIVSAVANRMDQTSSEIVRTMLRMS-EITTSSSAPFTQP---------------------------LSSNEIFRSLPVGYN------------------------------------------------------------------------ISKQVLDQYLTLLADDPLEFVGKSGDSGGGMYVINLHKALASLATATLESVVQERFGSRCARIFRLVLQKKHIEQKQVEDFAMIPAKEAKDMLYKMLSENFMSLQEIPKTP--DHAPSRTFYLYTVNILSAARMLLHRCYKSIANLIERRQFETKENKRLLEKSQRVEAIIASMQATGAEEAQLQEIEEMITAPERQQLETLKRNVNKLDASEIQVDETIFLLESYIECTMKRQ-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZUX1-1", "uniprot_id": "RPC3_DANRE", "id": "Q7ZUX1-1", "name": "DNA-directed RNA polymerase III subunit RPC3", "aln": "----------------------------------------MTAQEVRLCGLLLQEHFGDVVENVGTHLIRNGVLTLRALAHETK-LALDLVKKSLCVLVQHGMCTFGPGRRGPAGPVEYHINCEHILHMLRYPRYIYTAKSLYGDTGELIVEEILQRGQMTMSSTVKTVADRLTHNMPEGQSMDYNEVVSAFSRLVETHFLQRCPPMASAESSGTGSAETPPAVTQPSNPESHPDCYKLPYISLSGHGKRRRSSEDGEADQRAAKKAKTD---SSECGDEGIHWQVNFERFHLHFRDQAIISAVSCKLDQTSGEIVRTMLRMS-EVTTSANAAFTQA---------------------------LSANEIFRALPSNYN------------------------------------------------------------------------IARPILDQYLTLLVDDPMEFVGKAGDSGGGMFVVNLHRALANLARATLESVVQERFGSRSARIFRLLLRKRHLEQKQVEDFAMIPAKEAKEMLYTLLSENLVQLQEIPKTP--DHAPSRTFYLYAVNQLPTARLLLQHCYKTVGNLIERRLYETKENKRLLEKSQRIEAILASLQATGAEATQLTEVEEMITAPERQQLESLRHHINKLDSGENQVDETIFLLESYINSTQASR-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VG60-1", "uniprot_id": "Q9VG60_DROME", "id": "Q9VG60-1", "name": "DNA-directed RNA polymerase III subunit RPC3", "aln": "----------------------------------------MSADYSHLSSAILEQCFGKVVQAVADCLFSATTRTLGQITSATK-LSRKEVAFALAVLVKFRLVDFAASKAN-PFLAEYALRREDVLCLLRYPRYVHLVQTKYGNVGASISEELINSGSDTATGILLKCLAENENKAESPE-----SYRNTFLEMITDHYIIKRPELLVGDDQDEN------VPKFETNEC---DFFRHPNIDLQLLAKIQKGEATLAEAR-----------------DSHMVWHLNHDRFHQDFRDTIMVDAIERKLGENAAECFKFILKIMYNTTDPWERKLSNQ---------------------------ITFVEIKQAIERKSNNL----------------------------------------------------------------------DLMKYLDQYISLLTEDSLGFFRRVGDMGGGVYVVDMEHAFESLAFACVECVITERFGSKAARIFRVIRCKKYIEQEDLQKEAMIPSKEAKSLAYNLFQEQFIHVKIIKKPGGGSNGPAKAFYLFQVKEKDTVRMLLDASYKSLYNTIERSNFEKNEHKGLIEKSQRLDSIVEAMKERGETDEYIAEIVETFTPPECEILNKVKNRIKTLSKAELTLDDTIFLLQMYQHHCTTLPTGIRKFK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32349-1", "uniprot_id": "RPC3_YEAST", "id": "P32349-1", "name": "DNA-directed RNA polymerase III subunit RPC3", "aln": "MDELLGEALSAENQTGESTVESEKLVTPEDVMTISSLEQRTLNPDLFLYKELVKAHLGERAASVIGMLVALGRLSVRELVEKIDGMDVDSVKTTLVSLTQLRCVKYLQETAISGKKTTYYYYNEEGIHILLYSGLIIDEIITQMRVNDEEEHKQLVAEIVQNVISLGSLTVEDYLSSVTSDSMKY-TISSLFVQLCEMGYLIQISKLHYTPIEDLWQFLYEKHYKNIPRNSPLSDLKKRSQAKMNAKTDFAKIINKPNELSQILTVDPKT---SLRIVKPTVSLTINLDRFMKGRRSKQLINLAKTRVGSVTAQVYKIALRLTEQKSPKIRDPLTQTGLLQDLEEAKSFQDEAELVEEKTPGLTFNAIDLARHLPAELDLRGSLLSRKPSDNKKRSGSNAAASLPSKKLKTEDGFVIPALPAAVSKSLQESGDTQEEDEEEEDLDADTEDPHSASLINSHLKILASSNFPFLN---ETKPGVYYVPYSKLMPVLKSSVYEYVIASTLGPSAMRLSRCIRDNKLVSEKIINSTALMKEKDIRSTLASLIRYNSVEIQEVPRTA--DRSASRAVFLFRCKETHSYNFMRQNLEWNMANLLFKKEKLKQENSTLLKKANRDDVKGREN--------------ELLLPSELNQLKMVNERELNVFAR---LSRLLSLWEVFQMA------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::: :*. . : *. .: :. . * :* * : : . * . : :* *. : .. .: : : . . . . . * .: :: : . : .. . . * . .: . : . : * :** *. ::. ::.. :.: : *:: : : :: :. :: : : : ::.::.:*... : *. : *:: : : : * : * *: . :*. . *: * : :: :.:: ::. *:: *: :. .:: : : :: : :. ....:::.:*: : : .:: . .: * : : .:*:. *::*::* : * : ..* : *: :... .: :. : * : : ", "identical_positions": 37, "similar_positions": 172, "identity": "5.35%" }, { "cls_id": "homologset.agr.SGD:S000006395", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P32551-1", "uniprot_id": "QCR2_RAT", "id": "P32551-1", "name": "Cytochrome b-c1 complex subunit 2, mitochondrial", "aln": "MKLLSRAGSFSRFYSLKVAPKLKTS-APGGVPLQPQELEFTKLPNGLVIASLENYAPLSRIGLFIKAGSRYENYNYLGTSHLLRLASTLTTKGASSFKITRGIEAVGGKLSVTATRENMAYTVEGIRDDIEILMEFLLNVTTAPEFRRWEVAALRS-QLKIDKAVAFQNPQTRIIENLHDVAYKNALANPLYCPDYRMGKITSEELHYFVQNHFTSARMALVGLGVSHSILKEVAEQFLNIRGGLGLAGAKAKYRGGEIREQNGDNLVHAAIVAESAAIG-NAEANAFSVLQHLLGAGPHIKRGNNTTSLLSQSVAKGSQQPFDVSAFNASYSDSGLFGIYTVSQAAAAGDVINAAYNQVKAVAQGNLSSADVQAAKNKLKAGYLMSVETSEGFLSEIGSQALATGSYMPPPTVLQQIDAVADADVVKAAKKFVSGKKSMTASGNLGHTPFLDEL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DB77-1", "uniprot_id": "QCR2_MOUSE", "id": "Q9DB77-1", "name": "Cytochrome b-c1 complex subunit 2, mitochondrial", "aln": "MKLLSRAGSFSRFYSLKVAPKVKTSAAPGGVPLQPQDLEFTKLPNGLVIASLENYAPLSRIGLFVKAGSRYEDSNNLGTSHLLRLASSLTTKGASSFKITRGIEAVGGKLSVTATRENMAYTVEGIRSDIEILMEFLLNVTTAPEFRRWEVAALRS-QLKIDKAVAFQNSQTRIIENLHDVAYKNALANPLYCPDYRMGKITSEELHYFVQNHFTSARMALVGLGVSHSVLKQVAEQFLNMRGGLGLAGAKAKYRGGEIREQNGDNLVHAAIVAESAAIG-NAEANAFSVLQHLLGAGPHIKRGNNTTSLLSQSVAKGSHQPFDVSAFNASYSDSGLFGIYTISQAAAAGEVINAAYNQVKAVAQGNLSSADVQAAKNKLKAGYLMSVETSEGFLSEIGSQALAAGSYMPPSTVLQQIDSVADADVVKAAKKFVSGKKSMAASGNLGHTPFLDEL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22695-1", "uniprot_id": "QCR2_HUMAN", "id": "P22695-1", "name": "Cytochrome b-c1 complex subunit 2, mitochondrial", "aln": "MKLLTRAGSFSRFYSLKVAPKVKATAAPAGAPPQPQDLEFTKLPNGLVIASLENYSPVSRIGLFIKAGSRYEDFSNLGTTHLLRLTSSLTTKGASSFKITRGIEAVGGKLSVTATRENMAYTVECLRGDVDILMEFLLNVTTAPEFRRWEVADLQP-QLKIDKAVAFQNPQTHVIENLHAAAYRNALANPLYCPDYRIGKVTSEELHYFVQNHFTSARMALIGLGVSHPVLKQVAEQFLNMRGGLGLSGAKANYRGGEIREQNGDSLVHAAFVAESAVAG-SAEANAFSVLQHVLGAGPHVKRGSNTTSHLHQAVAKATQQPFDVSAFNASYSDSGLFGIYTISQATAAGDVIKAAYNQVKTIAQGNLSNTDVQAAKNKLKAGYLMSVESSECFLEEVGSQALVAGSYMPPSTVLQQIDSVANADIINAAKKFVSGQKSMAASGNLGHTPFVDEL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VV75-1", "uniprot_id": "Q9VV75_DROME", "id": "Q9VV75-1", "name": "", "aln": "-----MACNASKTSLLRAIAKRGYATCPRPVG-DLSAVNVKVLENKLVVATADATLPVSRVSLVLGAGSRNESYDIQGASHLLRLAGGLSTQNSTAFAIARNIQQVGGTLTTWGDRELVGYTVTTTADNAETGLRYLQDLLQP-AFKPWELVDN---AKTVVNQLNAVSTEERAIELVHKAAFRNGLGNSIYSPRFQLGKLSSESLLHYVAQTFAAGRAAVVGVGIDNNTLAGFAQTLQFPSGGS--KAASANWYGGDARKDTSGHRAVVAVAGQGAAASNHKEALAFAILEQALGAKAATKRG-TSAGLFGEAVNCAGGVGASVKAVNASYSDAGLFGFVVSADSKDIG---KTVEFLVRGLKSASVSDKDVARGKALLKARIISRYSSDGGLIKEIGRQAALTRNVLEADALLGAIDGISQSQVQEAAKKVGSSKLAVGAIGHLANVPYASDLA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07257-1", "uniprot_id": "QCR2_YEAST", "id": "P07257-1", "name": "Cytochrome b-c1 complex subunit 2, mitochondrial", "aln": "-----------------MLSAARLQFAQGSVR-------------RLTVSARDAPTKISTLAVKVHGGSRYATKD--GVAHLLNRFNFQNTNTRSALKLVRESELLGGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVAEQCPVKSAEDQLYAITFRKGLGNPLLYDG--VERVSLQDIKDFADKVYTKENLEVSGENVVEADLKRFVDESLLSTLPAGKSLVSKSEPKFFLGEENRVRFIGDSVAAIGIPVN-KASLAQYEVLANYLTSALSELSGLISSAKLDK------------------FTDGGLFTLFVRDQD------SAVVSSNIKKIVADLKKGKDLSPAINYTKLKNAVQNESVSSPIELN----------------------------FDAVKDFKLGKFNYVAVGDVSNLPYLDEL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . *.::: : :* :.: : .*** . *.:***. . .*: ::: :.* : :**.:. ** : .. .: :. * :: *: *:. : . : :: ::::.*.*.: : ::: :.: :. : :: . : * .: . * ..: .. . ::. :... . . . : :* : * : * ::. : : ::*.*** : . : .. :: : .. *: . * .: :. .*.*.. .: * *.:.: *: .:* ", "identical_positions": 37, "similar_positions": 130, "identity": "8.11%" }, { "cls_id": "homologset.agr.SGD:S000006396", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51180-1", "uniprot_id": "MIP_MOUSE", "id": "P51180-1", "name": "Lens fiber major intrinsic protein", "aln": "--------------------------MWELR-------------------------SASFWRAIFAEFFATLFYVFFGLGASLRWAP-----------GPLHVLQVALAFGLALATLVQTVGHISGAHVNPAVTFAFLVGSQMSLLRAFCYIAAQLLGAVAGAAVLYSVTPPAVRGNLA------LNTLHAGVSVGQATTVEIFLTLQFVLCIFATYDERRNGRMGSVALAVGFSLTLGHLFGMYYTGAGMNPARSFAPAILTRNFS-NHWVYWVGPIIGGGLGSLLYDFLLFPRLKSVSERLSILKGARPSDS------NGQPEGTGEPVELKTQAL-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09011-1", "uniprot_id": "MIP_RAT", "id": "P09011-1", "name": "Lens fiber major intrinsic protein", "aln": "--------------------------MWELR-------------------------SASFWRAIFAEFFATLFYVFFGLGSSLRWAP-----------GPLHVLQVALAFGLALATLVQTVGHISGAHVNPAVTFAFLVGSQMSLLRAFCYIAAQLLGAVAGAAVLYSVTPPAVRGNLA------LNTLHAGVSVGQATTVEIFLTLQFVLCIFATYDERRNGRMGSVALAVGFSLTLGHLFGMYYTGAGMNPARSFAPAILTRNFS-NHWVYWVGPIIGGGLGSLLYDFLLFPRLKSVSERLSILKGARPSDS------NGQPEGTGEPVELKTQAL-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30301-1", "uniprot_id": "MIP_HUMAN", "id": "P30301-1", "name": "Lens fiber major intrinsic protein", "aln": "--------------------------MWELR-------------------------SASFWRAIFAEFFATLFYVFFGLGSSLRWAP-----------GPLHVLQVAMAFGLALATLVQSVGHISGAHVNPAVTFAFLVGSQMSLLRAFCYMAAQLLGAVAGAAVLYSVTPPAVRGNLA------LNTLHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFT-NHWVYWVGPIIGGGLGSLLYDFLLFPRLKSISERLSVLKGAKPDVS------NGQPEVTGEPVELNTQAL-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56402-1", "uniprot_id": "AQP2_MOUSE", "id": "P56402-1", "name": "Aquaporin-2", "aln": "--------------------------MWELR-------------------------SIAFSRAVLAEFLATLLFVFFGLGSALQWAS-----------SPPSVLQIAVAFGLGIGTLVQALGHVSGAHINPAVTVACLVGCHVSFLRAAFYVAAQLLGAVAGAAILHEITPVEIRGDLA------VNALHNNATAGQAVTVELFLTMQLVLCIFASTDERRSDNLGSPALSIGFSVTLGHLLGIYFTGCSMNPARSLAPAVVTGKFD-DHWVFWIGPLVGAVIGSLLYNYLLFPSTKSLQERLAVLKG-LEPDT----DWEEREVRRRQSVELHSPQSLPRGSKA------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P34080-1", "uniprot_id": "AQP2_RAT", "id": "P34080-1", "name": "Aquaporin-2", "aln": "--------------------------MWELR-------------------------SIAFSRAVLAEFLATLLFVFFGLGSALQWAS-----------SPPSVLQIAVAFGLGIGILVQALGHVSGAHINPAVTVACLVGCHVSFLRAAFYVAAQLLGAVAGAAILHEITPVEIRGDLA------VNALHNNATAGQAVTVELFLTMQLVLCIFASTDERRGDNLGSPALSIGFSVTLGHLLGIYFTGCSMNPARSLAPAVVTGKFD-DHWVFWIGPLVGAIIGSLLYNYLLFPSAKSLQERLAVLKG-LEPDT----DWEEREVRRRQSVELHSPQSLPRGSKA------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41181-1", "uniprot_id": "AQP2_HUMAN", "id": "P41181-1", "name": "Aquaporin-2", "aln": "--------------------------MWELR-------------------------SIAFSRAVFAEFLATLLFVFFGLGSALNWPQ-----------ALPSVLQIAMAFGLGIGTLVQALGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLA------VNALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFD-DHWVFWIGPLVGAILGSLLYNYVLFPPAKSLSERLAVLKG-LEPDT----DWEEREVRRRQSVELHSPQSLPRGTKA------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WTY4-1", "uniprot_id": "AQP5_MOUSE", "id": "Q9WTY4-1", "name": "Aquaporin-5", "aln": "-------------------------MKKEVC-------------------------SVAFFKAVFAEFLATLIFVFFGLGSALKWPS-----------ALPTILQISIAFGLAIGTLAQALGPVSGGHINPAITLALLIGNQISLLRAIFYVAAQLVGAIAGAGILYWLAPGNARGNLA------VNALSNNTTPGKAVVVELILTFQLALCIFSSTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPSHWVFWVGPIVGAVLAAILYFYLLFPSSLSLHDRVAVVKGTYEPEE----DWEDHREERKKTIELTAH---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47864-1", "uniprot_id": "AQP5_RAT", "id": "P47864-1", "name": "Aquaporin-5", "aln": "-------------------------MKKEVC-------------------------SLAFFKAVFAEFLATLIFVFFGLGSALKWPS-----------ALPTILQISIAFGLAIGTLAQALGPVSGGHINPAITLALLIGNQISLLRAVFYVAAQLVGAIAGAGILYWLAPLNARGNLA------VNALNNNTTPGKAMVVELILTFQLALCIFSSTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPSHWVFWVGPIVGAMLAAILYFYLLFPSSLSLHDRVAVVKGTYEPEE----DWEDHREERKKTIELTAH---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55064-1", "uniprot_id": "AQP5_HUMAN", "id": "P55064-1", "name": "Aquaporin-5", "aln": "-------------------------MKKEVC-------------------------SVAFLKAVFAEFLATLIFVFFGLGSALKWPS-----------ALPTILQIALAFGLAIGTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLA------VNALNNNTTQGQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPNSLSLSERVAIIKGTYEPDE----DWEEQREERKKTMELTTR---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C4A0-1", "uniprot_id": "AQP6_MOUSE", "id": "Q8C4A0-1", "name": "Aquaporin-6", "aln": "---------------MEPGLCSRAYLLVGGL-------------------------WTAISKALFAEFLATGLYVFFGVGSVLPWPV-----------ALPSVLQIAITFNLATATAVQISWKTSGAHANPAVTLAYLVGSHISLPRAMAYIAAQLAGATAGAALLYGVTPGGIRETLG------VNVVHNSTSTGQAVAVELVLTLQLVLCVFASMDGRQTL--ASPAAMIGTSVALGHLIGIYFTGCSMNPARSFGPAVIVGKFA-VHWIFWVGPLTGAVLASLIYNFILFPDTKTVAQRLAILVGTTKVEK--VVDLEPQKKESQTNSEDTECLTSPCEEAVRSFSFTLGLC--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WTY0-1", "uniprot_id": "AQP6_RAT", "id": "Q9WTY0-1", "name": "Aquaporin-6", "aln": "---------------MEPGLCNRAYLLVGGL-------------------------WTAISKALFAEFLATGLYVFFGVGSVLPWPV-----------ALPSVLQVAITFNLATATAVQISWKTSGAHANPAVTLAYLVGSHISLPRAVAYIAAQLAGATVGAALLYGVTPGGVRETLG------VNVVHNSTSTGQAVAVELVLTLQLVLCVFASMDSRQTL--GSPAAMIGTSVALGHLIGIYFTGCSMNPARSFGPAVIVGKFA-VHWIFWVGPLTGAVLASLIYNFILFPDTKTVAQRLAILVGTTKVEK--VVDLEPQKKESQTNSEDTEVSV-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13520-1", "uniprot_id": "AQP6_HUMAN", "id": "Q13520-1", "name": "Aquaporin-6", "aln": "------------MDAVEPGGRGWASMLACRL-------------------------WKAISRALFAEFLATGLYVFFGVGSVMRWPT-----------ALPSVLQIAITFNLVTAMAVQVTWKASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYGVMPGDIRETLG------INVVRNSVSTGQAVAVELLLTLQLVLCVFASTDSRQTS--GSPATMIGISVALGHLIGIHFTGCSMNPARSFGPAIIIGKFT-VHWVFWVGPLMGALLASLIYNFVLFPDTKTLAQRLAILTGTVEVGTGAGAGAEPLKKESQPGSGAVEMESV------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02013-1", "uniprot_id": "AQP1_MOUSE", "id": "Q02013-1", "name": "Aquaporin-1", "aln": "-------------------------MASEIK-------------------------KKLFWRAVVAEFLAMTLFVFISIGSALGFNYPLERNQT----LVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISILRAVMYIIAQCVGAIVATAILSGITSSLVDNSLG------RNDLAHGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVLTRNFS-NHWIFWVGPFIGGALAVLIYDFILAPRSSDFTDRMKVWTSGQVEEY----DLDADDINSRVEMKPK-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29975-1", "uniprot_id": "AQP1_RAT", "id": "P29975-1", "name": "Aquaporin-1", "aln": "-------------------------MASEIK-------------------------KKLFWRAVVAEFLAMTLFVFISIGSALGFNYPLERNQT----LVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISILRAVMYIIAQCVGAIVASAILSGITSSLLENSLG------RNDLARGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVLTRNFS-NHWIFWVGPFIGSALAVLIYDFILAPRSSDFTDRMKVWTSGQVEEY----DLDADDINSRVEMKPK-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29972-1", "uniprot_id": "AQP1_HUMAN", "id": "P29972-1", "name": "Aquaporin-1", "aln": "-------------------------MASEFK-------------------------KKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQT----AVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLG------RNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFS-NHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRVKVWTSGQVEEY----DLDADDINSRVEMKPK-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQ72-1", "uniprot_id": "A0A8M3AQ72_DANRE", "id": "A0A8M3AQ72-1", "name": "", "aln": "-------------------------MARELK-------------------------SWSFWRAVLAEFVGMTIFVFIGIASAIGNKH----NRY----PDQE-VKVALAFGLAIATLAQSLGHISGAHLNPAITLGLLVSCQISFFRAFMYIIAQMLGAVLASGIMFKVSPDP-DTTLG------LNMLGNGVKVGQGFAIELFATFQLVLCVLATTDKNRTDVSGSAPLAIGLSVGLGHLVAISYTGCGINPARSFGPAVVLESFK-NHWIYWIAPMCGGVAAALIYDFLLFPKREALRKRMNVLKGTADPDP----SATEALIEPRSARSGSGVAGAE-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P55088-1", "uniprot_id": "AQP4_MOUSE", "id": "P55088-1", "name": "Aquaporin-4", "aln": "----MSDGAAARRWGKCGHSCSRESIMVAFKGV----------------------WTQAFWKAVSAEFLATLIFVLLGVGSTINWGGS---ENP----LPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIIAQCLGAIIGAGILYLVTPPSVVGGLG------VTTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWA-NHWIYWVGPIMGAVLAGALYEYVFCPDVELKRRLKEAFSKAAQQTKGSYMEVEDNRSQVETEDLILKPGVVHVIDIDRGEEKKGKDSSGEVLSSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47863-1", "uniprot_id": "AQP4_RAT", "id": "P47863-1", "name": "Aquaporin-4", "aln": "----MSDGAAARRWGKCGPPCSRESIMVAFKGV----------------------WTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGS---ENP----LPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVVGGLG------VTTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWE-NHWIYWVGPIIGAVLAGALYEYVFCPDVELKRRLKEAFSKAAQQTKGSYMEVEDNRSQVETEDLILKPGVVHVIDIDRGDEKKGKDSSGEVLSSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55087-1", "uniprot_id": "AQP4_HUMAN", "id": "P55087-1", "name": "Aquaporin-4", "aln": "----MSDRPTARRWGKCGPLCTRENIMVAFKGV----------------------WTQAFWKAVTAEFLAMLIFVLLSLGSTINWGGT---EKP----LPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLG------VTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWE-NHWIYWVGPIIGAVLAGGLYEYVFCPDVEFKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETDDLILKPGVVHVIDVDRGEEKKGKDQSGEVLSSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V5Z7-1", "uniprot_id": "AQP_DROME", "id": "Q9V5Z7-1", "name": "Aquaporin", "aln": "--------------MVEKTEMSKFVGVADITE------------------------NKKIWRMLLGELVGTFFLIFVGVGSTT----------------SGSVPQIAFTFGLTVATIAQGLGHLSGCHINPAVTLGFLIVGEISILKAAFYIIVQCVGAIAGAAVIKVALDGVAGGDLG------VSSFDPSLNCAQAVLIEALITFILVFVVKAVSDPGRQDIKGSAPLAVGLAIAAGHLCAIKLSGASMNPARSFGPAVVQGVWT-YHWVYWVGPIAGGLLAGIIYRLIFK-----------VRKGDDETDS-----YDF-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0C4DHF9-1", "uniprot_id": "A0A0C4DHF9_DROME", "id": "A0A0C4DHF9-1", "name": "", "aln": "----MPVQQPQSAEIGHQMKMSSEEPPSGKQTC-----------RSQSNCWLLQRRQLDSITTVLAEMIATAMLMFLGCMGSVENSV-----------FTNSDFQSALNFGFVVLICIQCFGCVCGAHLNPAVTLATYVYNMISLPMALAYFVAQMVGAFIGYGLLKAVLPESAIYSAENPNGVCLTSLNSTLTPWQGLAVEFLITCVLISVCCGVWDPRNATKQDSLPVRFGLAIACLSLTAGQLTGASMNPVRSFAPAIWNGFWD-DHWIYWVGPMAAALITSVIYKHAFRRELEESEVDETTMSTKRTSEAELA----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W1M2-1", "uniprot_id": "Q9W1M2_DROME", "id": "Q9W1M2-1", "name": "", "aln": "--------------MSQQKQKSQESNPNAR--------------------WRLEGHQRSAIACFFGELAATAVFVFIACMGCVETPL-----------FQNSHFRSGLTFGLAILIAIQCFGSVSGAHLNPAITLAAWLYGAIGWIRAIAYFVAQAAGALIGYGLLVAVLPGNSIKGVDNPSGVCVTILAPGISVLQGVFIEFLITCCLVMVACSVWDPRNAKLQDSVPVRFGLTVSCLILTAGLFTGASMNPTRSLGPAVWNDSWA-HHWIYWVGPLVAGAVTSLIYRMAFKGD-EEIDLRTSDAKIRMIGEVIVQ----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KFZ1-1", "uniprot_id": "A0A0B4KFZ1_DROME", "id": "A0A0B4KFZ1-1", "name": "", "aln": "----MIDEVPKQVYLESRKRWTMACDREGSSLFSVALFKRFSDHFSCCKVFKMKGSTLDKISAFLGELIGTGILVFLGCMGCVKTDL-----------FPNNHLQIVLNFGFAVLIAIQCFGCVSGAHLNPAVTVAAYIYEMVTLRMAFAYFAAQMLGAFIGYGLLMVLLPSPTLTVG---AGLCVTLPHTSVTTGQALGIEFVITSILVIVCCGVWDPRNSKFHDSVGIRFGLAIACLACAAGPFTGGSMNPARSFAPALWNKHFE-SNWIYWLAPLSSSAITAYAYKVVFRREVVEAEITS-NEKLRQLEDVQLS----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W1M4-1", "uniprot_id": "Q9W1M4_DROME", "id": "Q9W1M4-1", "name": "", "aln": "-----------------------------------------------------MIWDFFTFIRGATEFSATALLILLGCMGDSTNQG-----------GESKFLVASVHYGLTVMVVMHVFGFVSGAHSNPCISISCYLMGYIALEVMMMYVVCQMAGAFLGYFLLMQLLPKELVDKSK--PGICLVQPMDTLSTYQVVIIECLLTAVLVLGWCSLWDVRNGRFLDSVAIRMGLLVIACSFAGIQLTGASMNPAKTLVPAIFYGSPN-SVLMQLTGQILAAIMVPFVWNHAYTPPYKPLEIPVCN----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P56404-1", "uniprot_id": "AQP8_MOUSE", "id": "P56404-1", "name": "Aquaporin-8", "aln": "----MSGEQTPMCSMDLPEVKVK-TSMAGRCR---------------------VFWYEQYVQPCIVELVGSALFIFIGCLSVIENSP------------NTGLLQPALAHGLALGLIIATLGNISGGHFNPAVSLAVTVIGGLKTMLLIPYWISQLFGGLIGAALAKVVSPEERFWNASG---AAFAIVQEQEQVAEALGIEIILTMLLVLAVCMG-AVNEKTMGPLAPFSIGFSVIVDILAGGSISGACMNPARAFGPAVMAGYWD-FHWIYWLGPLLAGLFVGLLIRLLIGDEKTRLILKSR-----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56405-1", "uniprot_id": "AQP8_RAT", "id": "P56405-1", "name": "Aquaporin-8", "aln": "----MSGEQTPMCSMDLREIKGKETNMADSYHG--------------------MSWYEQYIQPCVVELLGSALFIFIGCLSVIENSP------------NTGLLQPALAHGLALGLIIATLGNISGGHFNPAVSLAVTLVGGLKTMLLIPYWVSQLFGGMIGAALAKVVSPEERFWNASG---AAFAIVQEQEQVAEALGVEIVMTMLLVLAVCMG-AVNEKTMGPLAPFSIGFSVIVDILAGGGISGACMNPARAFGPAVMAGYWD-FHWIYWLGPLLAGLFVGLLIRLFIGDEKTRLILKSR-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1NFX9-1", "uniprot_id": "A0A8M1NFX9_DANRE", "id": "A0A8M1NFX9-1", "name": "", "aln": "----MADDKMEKAAMDK---MVQETEMEEPGL------------------------FEQLVQPCMAELVGTAFFVLMGCLCVIESAQ------------EGHTLQAALVHGLALAVVIGCMVEISGSHFNPSFTIAVFLSGGLELKMVLPYLISQVSGGLLGAVMAKGMTSSEKYAQAQG---AAFTVLQADDHIMKALFAEAAMTCLATLAVLLS-AVNGKSKNHMFPFLVGCTVMVNVLAGANVSGACLNPVRALGPAVLTNYWT-HHWIYWVGPITGGLIAAALVRLFLGDNDTRVVMK-------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P0CD91-1", "uniprot_id": "AQY1_YEAST", "id": "P0CD91-1", "name": "Aquaporin-1", "aln": "MSSNDSNDTDKQHTRLDPTGVDDAYIPPEQPETKHHR------------FKISRDTLRDHFIAAVGEFCGTFMFLWCAYVICNVANHDVALVAAPDGSHPGQLIMIAIGFGFSVMFSIWCFAGVSGGALNPAMSLSLCLARAVSPTRCVVMWVSQIVAGMAAGGAASAMTPGEVLFANS---------LGLGCSRTRGLFLEMFGTAILCLTVLMTAVEKRETN-FMAALPIGISLFIAHVALTAYTGTGVNPARSLGAAVAARYFPHYHWIYWIGTLLGSILAWSVWQLLQILDYTTYVTAEKAASTKEKAQKKGETSSSSAVAEV------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . . : . . ..: .* **..:.. : * .. . . * * .* : :* :**.::: .*: : . : .. ", "identical_positions": 12, "similar_positions": 35, "identity": "3.31%" }, { "cls_id": "homologset.agr.SGD:S000006397", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P8J2-1", "uniprot_id": "SAT2_MOUSE", "id": "Q6P8J2-1", "name": "Thialysine N-epsilon-acetyltransferase", "aln": "-----MASTRIREARESDCGDIMRMIRELAEFEKLSHQVKISEEALRADGFGENPFFHCLVAEIIPAPGESQGSLVVGYGLYYFIYSTWTGR-NVYLEDIYVMPQYRGQGIGTKIIKKVAEVALNKGCSQFRLAVLDWNKKAVNLYKFLGAQDLTESEGWLSFRFEGEAMRELAGR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LBE2-1", "uniprot_id": "A0ABK0LBE2_RAT", "id": "A0ABK0LBE2-1", "name": "", "aln": "-----MASTRIREAKESDCGDIMRMIRELAEFEKLSHQVKISEEALRADGFGENPFFHCLVAEIIPAPGEPQGSLVVGYGLYYFIYSTWTGR-NIYLEDIYVMPKYRGQGIGTKIIKKVAEVALRKGCSQFRLAVLNWNKKAVNLYKFLGAQDLTESEGWLSFRFEGEAMRELAGC--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96F10-1", "uniprot_id": "SAT2_HUMAN", "id": "Q96F10-1", "name": "Thialysine N-epsilon-acetyltransferase", "aln": "-----MASVRIREAKEGDCGDILRLIRELAEFEKLSDQVKISEEALRADGFGDNPFYHCLVAEILPAPGKLLGPCVVGYGIYYFIYSTWKGR-TIYLEDIYVMPEYRGQGIGSKIIKKVAEVALDKGCSQFRLAVLDWNQRAMDLYKALGAQDLTEAEGWHFFCFQGEATRKLAGK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48026-1", "uniprot_id": "SAT1_MOUSE", "id": "P48026-1", "name": "Diamine acetyltransferase 1", "aln": "-----MAKFKIRPATASDCSDILRLIKELAKYEYMEDQVILTEKDLQEDGFGEHPFYHCLVAEVPKEHWTPEGHSIVGFAMYYFTYDPWIGK-LLYLEDFFVMSDYRGFGIGSEILKNLSQVAMKCRCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLFKIDKEYLLKMAAEE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21673-1", "uniprot_id": "SAT1_HUMAN", "id": "P21673-1", "name": "Diamine acetyltransferase 1", "aln": "-----MAKFVIRPATAADCSDILRLIKELAKYEYMEEQVILTEKDLLEDGFGEHPFYHCLVAEVPKEHWTPEGHSIVGFAMYYFTYDPWIGK-LLYLEDFFVMSDYRGFGIGSEILKNLSQVAMRCRCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLFKIDKEYLLKMATEE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IHX8-1", "uniprot_id": "A0A0R4IHX8_DANRE", "id": "A0A0R4IHX8-1", "name": "", "aln": "------MRFTISAAKPEDCKDIERMIMELAVYENMPDQVKISHKELERDGFGPNPFYHCLVAEVPEEHKSKDGNTTVGYVIFFYTYSTWKGR-TVYMEDLYVMPEFRGNGIGKALLGAVAKEAKDQLCSRLQFSVLDWNKPSLYFYMAKGAEDLTAKEGWHFLRFHGMALDNLAQEAP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06592-1", "uniprot_id": "HPA2_YEAST", "id": "Q06592-1", "name": "Histone acetyltransferase HPA2", "aln": "MSNTSEDNITVRFVTENDKEGWQRLWKSYQDFYEVS-----FPDDLDDFNFG--RFLDPNIKMWAAVAVESSSEKIIGMINFFNHMTTWDFKDKIYINDLYVDENSRVKGAGGKLIQFVYDEADKLGTPSVYWCTDESNHRAQLLYVKVGYKAPK-----ILYKRKGY----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * . *: . : : . * .** * . : . :* :: .* : :*::*::* . * * * :: : . * . . . : *. : :* * . . . ", "identical_positions": 18, "similar_positions": 37, "identity": "10.11%" }, { "cls_id": "homologset.agr.SGD:S000006434", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7U6-1", "uniprot_id": "D4A7U6_RAT", "id": "D4A7U6-1", "name": "U6 snRNA-associated Sm-like protein LSm3", "aln": "MADDVDQQ-QTTNTVEEPLDLIRLSLDERIYVKMRNDRELRGRLHAYDQHLNMILGDVEETVTTIEIDEETYEEIYKSTKRNIPMLFVRGDGVVLVAPPLR-----VG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62311-1", "uniprot_id": "LSM3_MOUSE", "id": "P62311-1", "name": "U6 snRNA-associated Sm-like protein LSm3", "aln": "MADDVDQQ-QTTNTVEEPLDLIRLSLDERIYVKMRNDRELRGRLHAYDQHLNMILGDVEETVTTIEIDEETYEEIYKSTKRNIPMLFVRGDGVVLVAPPLR-----VG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62310-1", "uniprot_id": "LSM3_HUMAN", "id": "P62310-1", "name": "U6 snRNA-associated Sm-like protein LSm3", "aln": "MADDVDQQ-QTTNTVEEPLDLIRLSLDERIYVKMRNDRELRGRLHAYDQHLNMILGDVEETVTTIEIDEETYEEIYKSTKRNIPMLFVRGDGVVLVAPPLR-----VG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IMX8-1", "uniprot_id": "Q8IMX8_DROME", "id": "Q8IMX8-1", "name": "U6 snRNA-associated Sm-like protein LSm3", "aln": "MADETEQLSQVILPVKEPLDLIRLSLDEKVYVKMRNERELRGRLHAFDQHLNMVLGDAEETVTTVEIDEETYEEVYKTAKRTIPMLFVRGDGVILVSPPMR-----VG-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P57743-1", "uniprot_id": "LSM3_YEAST", "id": "P57743-1", "name": "LSM complex subunit LSM3", "aln": "--------------METPLDLLKLNLDERVYIKLRGARTLVGTLQAFDSHCNIVLSDAVETIYQLNN-----EELSESERR-CEMVFIRGDTVTLISTPSEDDDGAVEI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ****::*.***::*:*:*. * * * *:*:*.* *::*.*. **: :: **: :: :* *:*:*** * *::.* . * ", "identical_positions": 35, "similar_positions": 30, "identity": "32.11%" }, { "cls_id": "homologset.agr.SGD:S000006435", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V6A6-1", "uniprot_id": "G3V6A6_RAT", "id": "G3V6A6-1", "name": "", "aln": "-----MSNMEKHLFNLK--FAAKELNRNAKKCDKEEKAEKAKIKKAIQKGNTEVARIHAENAIRQKNQAINFLRMSARVDAVAARVQTAVTMGKVTKSMAGVVKSMDATLRSMNLEKISALMDKFEHQFETLDVQTQQMEDTMSSTTTLTTPQNQVDMLLQEMADEAGLDLNMELPQGQTGS--VGASVASTEQ--DELSQRLARLRDQV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQD4-1", "uniprot_id": "CH1B2_MOUSE", "id": "Q9CQD4-1", "name": "Charged multivesicular body protein 1B2", "aln": "-----MSNMEKHLFNLK--FAAKELNRNAKKCDKEEKAEKAKIKKAIQKGNTEVARIHAENAIRQKNQAINFLRMSARVDAVAARVQTAVTMGKVTKSMAGVVKSMDATLRSMNLEKISALMDKFEHQFETLDVQTQQMEDTMSSTTTLTTPQNQVDMLLQEMADEAGLDLNMELPQGQTGS--VGASVASTEQ--DELSQRLARLRDQV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7LBR1-1", "uniprot_id": "CHM1B_HUMAN", "id": "Q7LBR1-1", "name": "Charged multivesicular body protein 1b", "aln": "-----MSNMEKHLFNLK--FAAKELSRSAKKCDKEEKAEKAKIKKAIQKGNMEVARIHAENAIRQKNQAVNFLRMSARVDAVAARVQTAVTMGKVTKSMAGVVKSMDATLKTMNLEKISALMDKFEHQFETLDVQTQQMEDTMSSTTTLTTPQNQVDMLLQEMADEAGLDLNMELPQGQTGS--VGTSVASAEQ--DELSQRLARLRDQV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99LU0-1", "uniprot_id": "CH1B1_MOUSE", "id": "Q99LU0-1", "name": "Charged multivesicular body protein 1B1", "aln": "-----MSNMEKHLFNLK--FAAKELNRSSKKCDKEEKAEKAKIKKAIQKGNMEVARIHAENAIRQKNQGVNFLRMSARVDAVAARVQTAVTMGKVTKSMAGVVKSMDATLKSMNLEKISALMDKFEHQFETLDVQTQQMEDTMSSTTTLTTPQNQVDMLLQEMADEAGLDLNMELPQGQTGS--VGTSVASAEQ--DELSQRLARLRDQV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7ZVB1-1", "uniprot_id": "CHM1B_DANRE", "id": "Q7ZVB1-1", "name": "Charged multivesicular body protein 1b", "aln": "-----MSSMEKHLFNLK--FAAKELQRNSKKCDKEEKAEKVKVKKAIQKGNMEVARIHAENAIRQKNQSVNFLRMSARVDAVAARVQTAVTMNQVTKSMAGVVKGMDATLKSMNLEKISGLMEKFERQFETLDVQTAQMEDSMSSTTTLTTPQGQVDTLMMEMADEAGLDLNMELPQGQTGS--VGTSVASAEQ--DELSQRLAKLRDQV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q921W0-1", "uniprot_id": "CHM1A_MOUSE", "id": "Q921W0-1", "name": "Charged multivesicular body protein 1a", "aln": "--------MDDTLFQLK--FTAKQLEKLAKKAEKDSKAEQAKVKKALQQKNVECARVYAENAIRKKNEGVNWLRMASRVDAVASKVQTAVTMKGVTKNMAQVTKALDKALSAMDLQKVSAVMDRFEQQVQNLDVHTSVMEDSVSSATTLTTPQEQVDSLIVQIAEENGLEVLDQLSQLPEGASAVGESSVRSQE--DQLSRRLAALRN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GLB8-1", "uniprot_id": "A0A8I6GLB8_RAT", "id": "A0A8I6GLB8-1", "name": "", "aln": "--------MSDWTYILRPCFTAKQLEKLAKKAEKDSKAEQAKVKKALQQKNVECARVYAENAIRKKNEGVNWLRMASRVDAVASKVQTAVTMKGVTKNMAQVTKALDKALSAMDLQKVSAVMDRFEQQVQNLDVHTSVMEDSVSSATTLTTPQEQVDSLIVQIAEENGLEVLDQLSQLPEGASAVGESSVRSQE--DQLSRRLAALRN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HD42-1", "uniprot_id": "CHM1A_HUMAN", "id": "Q9HD42-1", "name": "Charged multivesicular body protein 1a", "aln": "--------MDDTLFQLK--FTAKQLEKLAKKAEKDSKAEQAKVKKALLQKNVECARVYAENAIRKKNEGVNWLRMASRVDAVASKVQTAVTMKGVTKNMAQVTKALDKALSTMDLQKVSSVMDRFEQQVQNLDVHTSVMEDSMSSATTLTTPQEQVDSLIMQIAEENGLEVLDQLSQLPEGASAVGESSVRSQE--DQLSRRLAALRN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PHF0-1", "uniprot_id": "CHM1A_DANRE", "id": "Q6PHF0-1", "name": "Charged multivesicular body protein 1a", "aln": "--------MDDTLFQLK--FTSKQLERLAKKAEKDSKSEQAKVKKALQQKNVECARVYAENAIRKKNEGLNWLRMASRVDAVASKVQTALTMKGVAKNMTQVTKALDKALSSMDLQKVSAVMDKFETQVQNLDVHTSVMEDSMSSATTLSTPQQQVDDLILQIAEESGLEVEDQLSQLPAGASALGETSARAQEKEDQLSRRLAALRN--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P69771-1", "uniprot_id": "DID2_YEAST", "id": "P69771-1", "name": "Vacuolar protein-sorting-associated protein 46", "aln": "MSRNSAAGLENTLFQLK--FTSKQLQKQANKASKEEKQETNKLKRALNE-NEDISRIYASNAIRKKNERLQLLKLASRVDSVASRVQTAVTMRQVSASMGQVCKGMDKALQNMNLQQITMIMDKFEQQFEDLDTSVNVYEDMGVNSDAMLVDNDKVDELMSKVADENGMELKQSAKLDNVPEIKAKEVNVDDEK-EDKLAQRLRALRG--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. : *: *::*:*.: ::*..*:.* * *:*:*: : * : :*::*.****:**: :: *::::***:**::****:** *: .* * *.:* :* *:*:::: :*::** *.: **. . ** .: :: . : :** *: ::*:* *::: . . :: *:*::** **. ", "identical_positions": 60, "similar_positions": 76, "identity": "28.57%" }, { "cls_id": "homologset.agr.SGD:S000006436", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P47198-1", "uniprot_id": "RL22_RAT", "id": "P47198-1", "name": "Large ribosomal subunit protein eL22", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPVKKLVA-----KGGKKKKQVLKFTLDCTHPVEDGIMDAANFEQFLQERIKVNGKAGNLGGGVVTIERSK-SKITVTSEEPFSKRYLKYLTKKYLKKNNLRDWLRVVANSKESYELRYFQINQDEEEEEDED-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P67984-1", "uniprot_id": "RL22_MOUSE", "id": "P67984-1", "name": "Large ribosomal subunit protein eL22", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPVKKLVA-----KGGKKKKQVLKFTLDCTHPVEDGIMDAANFEQFLQERIKVNGKAGNLGGGVVTIERSK-SKITVTSEVPFSKRYLKYLTKKYLKKNNLRDWLRVVANSKESYELRYFQINQDEEEEEDED-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35268-1", "uniprot_id": "RL22_HUMAN", "id": "P35268-1", "name": "Large ribosomal subunit protein eL22", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPVKKLVV-----KGGKKKKQVLKFTLDCTHPVEDGIMDAANFEQFLQERIKVNGKAGNLGGGVVTIERSK-SKITVTSEVPFSKRYLKYLTKKYLKKNNLRDWLRVVANSKESYELRYFQINQDEEEEEDED-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D7S7-1", "uniprot_id": "RL22L_MOUSE", "id": "Q9D7S7-1", "name": "Ribosomal protein eL22-like 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPQK----------DKKPKKSTWRFHLDLTHPVEDGIFDSGNFEQFLREKVKVNGKTGNLG-NVVHIERLK-NKITVVSEKQFSKRYLKYLTKKYLKKNNLRDWLRVVASDKETYELRYFQISQDEDGSESED-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZSF9-1", "uniprot_id": "D3ZSF9_RAT", "id": "D3ZSF9-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPQK----------DKKPKKSTWRFHLDLTHPVEDGIFDSGNFEQFLREKVKVNGKTGNLG-NVVHIERLK-NKITVVSEKQFSKRYLKHLTKKYLKKNNLRDWLRVVASDKETYELRYFQISQDEDGSESED-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P5R6-1", "uniprot_id": "RL22L_HUMAN", "id": "Q6P5R6-1", "name": "Ribosomal protein eL22-like", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPQK----------DRKPKRSTWRFNLDLTHPVEDGIFDSGNFEQFLREKVKVNGKTGNLG-NVVHIERFK-NKITVVSEKQFSKRYLKYLTKKYLKKNNLRDWLRVVASDKETYELRYFQISQDEDESESED-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JZA6-1", "uniprot_id": "A0A0G2JZA6_RAT", "id": "A0A0G2JZA6-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K----------DKKPKKSTWRFHLDLTHPVEDEIFDSENFEQFLQEKVKVNGKTGNLG-NVVHIECLK-NKITVVSEKQLSKRYLKYLTKKYLRKNNLCDWLHVVASDKETYELHYFQISQDEDGSESED-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50887-1", "uniprot_id": "RL22_DROME", "id": "P50887-1", "name": "Large ribosomal subunit protein eL22", "aln": "-MAPTAKTNKGDTKTAAAKPAEKKAAPAAAAAKGKV--EKPKAEAAKPAAAAAKNVKKASEAAKDVKAAAAAAKPAAAKPAAAKPAAASKDAGKKAPAAAAPKKDAKAAAAPAPAKAAPAKKAASTPAAAPPAKKAAPAKAAAPAAAAPAPAAAAPAVAKPAPKPKAKAAPAPSKVVKKNVLRGKGQKKKKVSLRFTIDCTNIAEDSIMDVADFEKYIKARLKVNGKVNNLG-NNVTFERSK-LKLIVSSDVHFSKAYLKYLTKKYLKKNSLRDWIRVVANEKDSYELRYFRISSNDDEDDDAE-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W1T1-1", "uniprot_id": "Q9W1T1_DROME", "id": "Q9W1T1-1", "name": "Large ribosomal subunit protein eL22", "aln": "MSSQTQKKNASKAKSKAGPQPSKKAPAKVTPVETATPSAAPPLSSKKVAKAPAVALKNLDLAMKESAKKAAEAADQKLVSKAKKGQNASRKNLMQVPEPVAPEVDNKKKSAPPKRGNAEIPTVVPAKKAALVQEKPKEQAAAAPKAENVEVPAAKAKSVKKSLATPANPKPKPKRTKNVLR--GKRLAKKKAWQRFVIDCACVAEDMILDLADFEQYLKTHIKIKNKLNQLK-DQVTFERTKNFSLIIHSGVHFSKRYFKYLTKRYLKKVSLRDWLRVVSTAKDTFAMTYFKIQDKDFDDDDDDVADDNGGKTFA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P56628-1", "uniprot_id": "RL22B_YEAST", "id": "P56628-1", "name": "Large ribosomal subunit protein eL22B", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPNT-----------SRKQKVIKTLTVDVSSPTENGVFDPASYSKYLIDHIKVDGAVGNLG-NAIEVTEDG-SIVTVVSSAKFSGKYLKYLTKKYLKKNQLRDWIRFVSIRQNQYKLVFYQVTPEDADEEEDDE----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : :* : .*: ::* .:.::: ::*:.. .:* . : . : : * :* *:*:***:**:* .* **::.*: :: : : :::: .: .:. : ", "identical_positions": 19, "similar_positions": 51, "identity": "6.03%" }, { "cls_id": "homologset.agr.SGD:S000006437", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P25886-1", "uniprot_id": "RL29_RAT", "id": "P25886-1", "name": "Large ribosomal subunit protein eL29", "aln": "-------------------------------------------------------MAKSKNHTTHNQSRKWHRNGIKKPRSQRYESLKGVDPKFLRNMRFAKKHNKKGLKKMQANNAKAVSARAEAIKALVKPQAVKPKMPKGSSRKLSRLAFIAHPKLGKKIRSYMAKGRRLCQPKPKVQTKA--EAKAPAKAQAKAPAQAPK------GAQAPVKAP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0R665-1", "uniprot_id": "M0R665_RAT", "id": "M0R665-1", "name": "Large ribosomal subunit protein eL29", "aln": "MEIRNGFSMLPPLQPTRFLSKSEVKGPEHMVMREHSDGQVDDSPGAAGAAAYRADMAKSKNHTTHNQSRKWHRNGIKKPWSQRYESLKGVDPKFLRNMRFAKKHNKKGLKKMQANNAKAVSARAEAIKALVKPQAVKPKMPKGSSRKLSRLAFIAHPKLGKKIRSYMAKGRRLCQPKPKVQTKA--EAKAPAKAQAKAPAQASK------GAQAPVKAP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZTF4-1", "uniprot_id": "A0A8I5ZTF4_RAT", "id": "A0A8I5ZTF4-1", "name": "60S ribosomal protein L29", "aln": "-------------------------------------------------------MAKSKNHTTHNQSRKWHRNGIKKPRSQRYKSLKGVDAKFLRNMRFAKKHNKKGLKKMQANNAKAVSARAEAIKALVKPQAVKPKMPKGSSRKLSRLAFIAHPKLGKKIRNYMAKGRRLCQPKPKVQTKA--EAKAPAKAQAKAPAQAPK------GAQAPVKAP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LFL1-1", "uniprot_id": "A0ABK0LFL1_RAT", "id": "A0ABK0LFL1-1", "name": "60S ribosomal protein L29", "aln": "-------------------------------------------------------MAKSKNHTTHNQSRKWHRNGIKKPRSQRYESLKGVDPKFLRNMRFAKKHNKKGLKKMQANNAKAVSARAEAIKALVKPQAVKPKMPKGSSRKLSRLVFIAHPKLGKKIRSYMAKGRRLCQPKPKVQTKA--EAKAPAKAQAKAPAQAPR------GAQAPVKAP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47915-1", "uniprot_id": "RL29_MOUSE", "id": "P47915-1", "name": "Large ribosomal subunit protein eL29", "aln": "-------------------------------------------------------MAKSKNHTTHNQSRKWHRNGIKKPRSQRYESLKGVDPKFLRNMRFAKKHNKKGLKKMQANNAKAVSARAEAIKALVKPQAIKPKMPKGP--KLKRLAFIAHPKLGKRIRSYMAKGQRLCQPKPKVQTKA--GAKAPAKAQASAPAQAPKGAQAPKGAQAPVKAP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "W4VSN7-1", "uniprot_id": "W4VSN7_MOUSE", "id": "W4VSN7-1", "name": "60S ribosomal protein L29", "aln": "-------------------------------------------------------MAKSKNHTTHNQSRKWHRNGIKKPRSQRYESLKGVDPKFLRNMRFAKKHNKKGLEKMQASNAKAVSVHAEAIKALVKPQAIKPKMPKGP--KLKRLAFIAHPKLGKRIRSYMAKGQRLCQPKPKVQTKA--GAKAPAKAQASTPAQAPKGAQAPKGAQAPVKAP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47914-1", "uniprot_id": "RL29_HUMAN", "id": "P47914-1", "name": "Large ribosomal subunit protein eL29", "aln": "-------------------------------------------------------MAKSKNHTTHNQSRKWHRNGIKKPRSQRYESLKGVDPKFLRNMRFAKKHNKKGLKKMQANNAKAMSARAEAIKALVKPKEVKPKIPKGVSRKLDRLAYIAHPKLGKRARARIAKGLRLCRPKAKAKAKAKDQTKAQAAAPASVPAQAPK------RTQAPTKASE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05747-1", "uniprot_id": "RL29_YEAST", "id": "P05747-1", "name": "Large ribosomal subunit protein eL29", "aln": "-------------------------------------------------------MAKSKNHTAHNQTRKAHRNGIKKPKTYKYPSLKGVDPKFRRN----HKHALHG-------TAKALAAAKK-----------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q24154-1", "uniprot_id": "RL29_DROME", "id": "Q24154-1", "name": "Large ribosomal subunit protein eL29", "aln": "-------------------------------------------------------MAKSKNHTNHNQNKKAHRNGIKRPLRKRHESTLGMDVKFLINQRYARKGNLSREESVKRYNERIASQKGK-------PKPVTL----------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******** ***.:* ******:* :: * *:* ** * :* . : : : ", "identical_positions": 26, "similar_positions": 11, "identity": "11.82%" }, { "cls_id": "homologset.agr.SGD:S000006438", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LZ43-1", "uniprot_id": "A0ABK0LZ43_RAT", "id": "A0ABK0LZ43-1", "name": "60S ribosomal protein L36", "aln": "MALRYPMAVGLNKGHKVT------------------------KNVSKPRHSRRR-GRLTKHTKFVRDMIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNVLAAMRKAAAKKD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZZ95-1", "uniprot_id": "D3ZZ95_RAT", "id": "D3ZZ95-1", "name": "60S ribosomal protein L36", "aln": "MALRYPMAVGLNKGHKVT------------------------KNVSKPRHSRRRRGRLTKHTKFVRDMIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNVLAAMRKAAAKKD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47964-1", "uniprot_id": "RL36_MOUSE", "id": "P47964-1", "name": "Large ribosomal subunit protein eL36", "aln": "MALRYPMAVGLNKGHKVT------------------------KNVSKPRHSRRR-GRLTKHTKFVRDMIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNVLAAMRKAAAKKD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M706-1", "uniprot_id": "F1M706_RAT", "id": "F1M706-1", "name": "60S ribosomal protein L36", "aln": "MALRYPMAMGLNKGHKVT------------------------KNVSKPRHSRRR-GRLTKHTKFVRDMIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKKVG-THIR------AKRKREELSNVLAAMRKAAAKKD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A1Q0-1", "uniprot_id": "D4A1Q0_RAT", "id": "D4A1Q0-1", "name": "Large ribosomal subunit protein eL36", "aln": "MALRYPMAVGLNKGHKVT------------------------KNVSKPRHSRRR-GRLTKHTKFVRDMIREVCG--------FAPYQRRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNVLAAMRKAAAKD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0RCN1-1", "uniprot_id": "M0RCN1_RAT", "id": "M0RCN1-1", "name": "Large ribosomal subunit protein eL36", "aln": "MALRYPMAVGLNKSHKVT------------------------KNVSKTRHSRRR-GRLTKHTKFVRDMIPEVCG--------FAPYVRRTMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNVLAAMRKD--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6Q415-1", "uniprot_id": "RL36_DANRE", "id": "Q6Q415-1", "name": "Large ribosomal subunit protein eL36", "aln": "MVVRYPMAVGLNKGHKVT------------------------KNVSKPKHSRRR-GRLTKHAKFARDLIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNTLAAMRKAAAKKE---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P49630-1", "uniprot_id": "RL36_DROME", "id": "P49630-1", "name": "Large ribosomal subunit protein eL36", "aln": "MAVRYELAIGLNKGHKTSKIRN--------------VKYTGDKKVKGLRGSRLK-NIQTRHTKFMRDLVREVVG--------HAPYEKRTMELLKVSKDKRALKFLKRRLG-THIR------AKRKREELSNILTQLRKAQTHAK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O14455-1", "uniprot_id": "RL36B_YEAST", "id": "O14455-1", "name": "Large ribosomal subunit protein eL36B", "aln": "MAVKTGIAIGLNKGKKVT------------------------QMTPAPKISYKK-GAASNRTKFVRSLVREIAG--------LSPYERRLIDLIRNSGEKRARKVAKKRLG-SFTR------AKAKVEEMNNIIAASRRH--------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "C0HME6-1", "uniprot_id": "ALT36_HUMAN", "id": "C0HME6-1", "name": "RPL36 alternative reading frame protein", "aln": "MASEAEGAGTRGSGPRELSRYSPPPLLPVAVRSHGPTLPYGRGPQQGPQSDQEREQAQAQPTPRASDQTHQVRAGHDSGGVWLCPVRAARHGVTEGLQGQTGPQIYQEKGGDAHPRQEEAGGAEQRTGRHEESCCQERLSPSPALSLK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . * ... : : . : :. : . :: . .* : . : . :. :.: * :. * *: : . .: * ", "identical_positions": 7, "similar_positions": 33, "identity": "4.73%" }, { "cls_id": "homologset.agr.SGD:S000007222", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28042-1", "uniprot_id": "SSBP_RAT", "id": "P28042-1", "name": "Single-stranded DNA-binding protein, mitochondrial", "aln": "-----MFRRPVLQVFRQFVR---QESEVASSLVLERSLNRVQLLGRVGQDPVMRQVEGKNPVTIFSLATNEMWRSGDNEAYQMGDVSQKTTWHRISVFRPGLRDVAYQYVKKGARIFVEGKVDYGEYMDKNNVRRQATTIIADNIIFLSDQAREKPLNG--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CYR0-1", "uniprot_id": "SSBP_MOUSE", "id": "Q9CYR0-1", "name": "Single-stranded DNA-binding protein, mitochondrial", "aln": "-----MFRRPVLQVFRQFVR---HESEVASSLVLERSLNRVQLLGRVGQDPVMRQVEGKNPVTIFSLATNEMWRSGDSEVYQMGDVSQKTTWHRISVFRPGLRDVAYQYVKKGARIFVEGKVDYGEYMDKNNVRRQATTIIAGKKLVVHSVSG-CSLEGLA------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04837-1", "uniprot_id": "SSBP_HUMAN", "id": "Q04837-1", "name": "Single-stranded DNA-binding protein, mitochondrial", "aln": "-----MFRRPVLQVLRQFVR---HESETTTSLVLERSLNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGDSEVYQLGDVSQKTTWHRISVFRPGLRDVAYQYVKKGSRIYLEGKIDYGEYMDKNNVRRQATTIIADNIIFLSDQTKEKE-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A5I7-1", "uniprot_id": "SSBP_DANRE", "id": "B8A5I7-1", "name": "Single-stranded DNA-binding protein, mitochondrial", "aln": "-----MLRNASAQILKQFVR---HRT-TDASLTLEKSINKVQILGRVGQDPVMRQVEGRNPVTIFSMATNEMWRSGEGEPVGAGDVTQKTTWHRISVFKPGLRDVAYQYVKKGSRIFVEGKLDYGEYVDKNNVRRQATTIIADNIVFLSENLRDQ------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P54622-1", "uniprot_id": "SSBP_DROME", "id": "P54622-1", "name": "Single-stranded DNA-binding protein, mitochondrial", "aln": "MQHTRRMLNPLLTGLRNLPARGATTTTAAAPAKVEKTVNTVTILGRVGADPQLRGSQ-EHPVVTFSVATHTNYK------YENGDWAQRTDWHRVVVFKPNLRDTVLEYLKKGQRTMVQGKITYGEITDQQGNQKTSTSIIADDVLFFRDANN--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32445-1", "uniprot_id": "RIM1_YEAST", "id": "P32445-1", "name": "Single-stranded DNA-binding protein RIM1, mitochondrial", "aln": "-----MFLRTQARFFHATTK--------------KMDFSKMSIVGRIGSEFTEHTSANNNRYLKYSIAS-------------QPRRDGQTNWYNITVFNEPQINFLTEYVRKGALVYVEADAANYVFERDDGSKGTTLSLVQKDINLLKNGKKLEDAEGQENAASSE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. :: : .. : ::**:* : : .: :*:*: :* *:.: **. : :*::** ::.. .:. : : ::: . .. . ", "identical_positions": 12, "similar_positions": 44, "identity": "7.19%" }, { "cls_id": "homologset.agr.SGD:S000007223", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYK5-1", "uniprot_id": "LYAR_RAT", "id": "Q6AYK5-1", "name": "Cell growth-regulating nucleolar protein", "aln": "MVFFTCNACGESVKKIQVEKHVSICRNCECLSCIDCGKDFW-GDDYKNHVKCISEDQKYGGKGYEAKTHKGDVKQQAWIQKINELIKKPNVSPKVRELLQQISAFDNVPRKKAKFQNWMRNSLKVHSDSVLEQVWNIFSEAASSE----QDQQ-PPSHMAKPNTEVP-TKVPSTKTNGTTEEQTEAKKNKRERKEERQKSRKKEKKELKLENHQENLKGQKPKKRKKGQEAGHEAGGEDAAEANGAPEKKRARDAQASEEGADRNGGPAEDADEGPTKTAAGKRKRQKHSEVESDNKKKKMKLPGQPEEGEPEDHEAPSKGKFNWKGTIKAVLKQAPDNEISVKKLKKKVIAQYHAVMSD-HHTSEEELLAIFNKKISRNPTFKVLKDKVKLLK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08288-1", "uniprot_id": "LYAR_MOUSE", "id": "Q08288-1", "name": "Cell growth-regulating nucleolar protein", "aln": "MVFFTCNACGESVKKIQVEKHVSNCRNCECLSCIDCGKDFW-GDDYKSHVKCISEGQKYGGKGYEAKTHKGDAKQQAWIQKINELIKKPNVSPKVRELLQQISAFDNVPRKKAKFQNWMKNSLKVHSDSVLEQVWDIFSEASSSE----QDQQQPPSHTAKPHAEMPITKVPSAKTNGTTEEQTEAKKNKRERKEERQKNRKKEKKELKLENHQENLRGQKPKKRKKNQEAGHEAAGEEAAEASGPPEKKKAQGGQASEEGADRNGGPGEDAAEGQTKTAAGKRKRPKHSGAESGYKKKKMKLPEQPEEGEAKDHEAPSKGKFNWKGTIKAVLKQAPDNEISVKKLKKKVIAQYHAVMND-HHTSEEELLAIFNRKISRNPTFKVLKDRVKLLK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NX58-1", "uniprot_id": "LYAR_HUMAN", "id": "Q9NX58-1", "name": "Cell growth-regulating nucleolar protein", "aln": "MVFFTCNACGESVKKIQVEKHVSVCRNCECLSCIDCGKDFW-GDDYKNHVKCISEDQKYGGKGYEGKTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNSLKVHNESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPHAEIS-TKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKD-----------SASEEEARVGAGKRKR-RHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDE-HHRSEEELLVIFNKKISKNPTFKLLKDKVKLVK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PD89-1", "uniprot_id": "A0A8M1PD89_DANRE", "id": "A0A8M1PD89-1", "name": "Cell growth-regulating nucleolar protein", "aln": "MVFFTCDGCGESLKKAQVEKHLLKCRSCHVLSCIDCGADFR-GDDYKSHNRCISEDQKYGGRDFQARANKGDLKQQQWIERVQEAVSRPDVGSELQQVLRRLSVYENVPRKKAKFENWMRNCLKIHSPHLLKQVWEILSTAADSN-----------------------GKPASRETTENCESRTDLKNGTEEEEDQRKKKKKKNRKTSEEQNGHEKHTQKQKRKREQNEQN-----------TDGKNNKRQKKSKQEEP---------------DESLNEEG----------------------EEPDNQETEPN--STAGKFNWKGTIKAVLRDAPEEGLAVKKLRKKVLAAYYSFSGDRNYRSEEELLSLFNRKINTNPKFKILKDRVRLLK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P37263-1", "uniprot_id": "YC16_YEAST", "id": "P37263-1", "name": "UPF0743 protein YCR087C-A", "aln": "MVTFNCEVCNDTVPKKNTEKHYYRCPN-AYYTCIDCSKTFEDGVSYKNHTSCISEDEKYQKALYKGNKKQKQKQQQ----------KQQQKQHQHQPVATPAKKVEKPVIKKAEKVEKTSNGIELHKGKSLYKILKTMKDKGAKK---------------------------TFLKSLVVDSEGQIRYAKE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *.*: *.::: * :.*** * . :****. * * .**.* ****.:** ::.. :: : :** .: : : : : . :: ***: : * :::*. * :: . :. . .: : . :.. : : .. ", "identical_positions": 33, "similar_positions": 55, "identity": "8.38%" }, { "cls_id": "homologset.agr.SGD:S000007224", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RZ39-1", "uniprot_id": "RM36_RAT", "id": "B2RZ39-1", "name": "Large ribosomal subunit protein bL36m", "aln": "MAALFVRSVVASVVD----LSRLAVKP--------RAFS-ILLGTLP-------SAKPCAEVRSLLCG--GPVLSLQPSLGFKTKGVIKKRCRDCYMVKRRGRWFVLCKTNPKHKQRQM---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N90-1", "uniprot_id": "RM36_MOUSE", "id": "Q99N90-1", "name": "Large ribosomal subunit protein bL36m", "aln": "MAALLVRSVVASVVDPFLHLSRLAVKP--------RVFSSFLLGTLP-------RAKPCAEVRSVLCG--RPLPTLLPSLGFKTKGVIKKRCKDCYKVKRRGRWFILCKTNPKHKQRQM---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P0J6-1", "uniprot_id": "RM36_HUMAN", "id": "Q9P0J6-1", "name": "Large ribosomal subunit protein bL36m", "aln": "MANLFIRKMVNPLLY----LSRHTVKP--------RALSTFLFGSIRGAAPV--AVEPGAAVRSLLSP--GLLPHLLPALGFKNKTVLKKRCKDCYLVKRRGRWYVYCKTHPRHKQRQM---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LWG3-1", "uniprot_id": "RM36_DANRE", "id": "Q1LWG3-1", "name": "Large ribosomal subunit protein bL36m", "aln": "---MLLRSLVGSLTRQWSQFARCAASLSLPAVGAQRCLSTITAAAVPFRAVVNPMFKPHTAFLSPLLGRCQQLLCVQPSAGMKTKSALKKRCNECFFVRRRGRLFVFCKAHPRHKQRQG---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O14464-1", "uniprot_id": "RTC6_YEAST", "id": "O14464-1", "name": "Large ribosomal subunit protein bL36m", "aln": "---MFLQTLRLTMPR---MFLHMKPSP----------ITITRACTVP-------SLLSVAAPQPALVAANRPLVFNR---GFKVRTSVKKFCSDCYLVRRKGRVYIYCKSNKKHKQRQG---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9I7Q9-1", "uniprot_id": "Q9I7Q9_DROME", "id": "Q9I7Q9-1", "name": "Ribosomal protein", "aln": "--MSLASRILQQGSRLWNGLSAARGFH--------LLTRPAAPAIVSIQSSQLVAATTGICQTSGLLT--PGSTLVQQVAGFKVKGRLKRRCKDCYIVVRQERGYVICPTHPRHKQMSMKKRDYKSWILTHATQSKERGY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . . * *:* : :*: * :*: * *: * :: * :: :*** . ", "identical_positions": 13, "similar_positions": 19, "identity": "9.29%" }, { "cls_id": "homologset.agr.SGD:S000007228", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WV55-1", "uniprot_id": "VAPA_MOUSE", "id": "Q9WV55-1", "name": "Vesicle-associated membrane protein-associated protein A", "aln": "MASASGAMAKHEQILVLDPPSDLKFKGPFTDVVTTNLKLQNPSDRK-VCFKVKTTAPRRYCVRPNSGIIDPGSIVTVSVMLQ----PFDYDPNEKSKHKFMVQTIFAP--PNISDMEAVWKEAKPDELMDSKLRCVFEMPNENDKLNDMEPSKAV-------------PLNASKQDGPLP-KPHSVSLNDTETRKLMEECK---RLQGEMMKLSEENRHLR-DEGLRLR------KVAHSDKPGSTSAVSFRDNVTSPLPSLLVVIAAIFIGFFLGKFIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z270-1", "uniprot_id": "VAPA_RAT", "id": "Q9Z270-1", "name": "Vesicle-associated membrane protein-associated protein A", "aln": "MASASGAMAKHEQILVLDPPSDLKFKGPFTDVVTTNLKLQNPSDRK-VCFKVKTTAPRRYCVRPNSGVIDPGSIVTVSVMLQ----PFDYDPNEKSKHKFMVQTIFAP--PNISDMEAVWKEAKPDELMDSKLRCVFEMPNENDKLNDMEPSKAV-------------PLNASKQDGPLP-KPHSVSLNDTETRKLMEECK---RLQGEMMKLSEENRHLR-DEGLRLR------KVAHSDKPGSTSAVSFRDNVTSPLPSLLVVIAAIFIGFFLGKFIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P0L0-1", "uniprot_id": "VAPA_HUMAN", "id": "Q9P0L0-1", "name": "Vesicle-associated membrane protein-associated protein A", "aln": "MASASGAMAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRK-VCFKVKTTAPRRYCVRPNSGIIDPGSTVTVSVMLQ----PFDYDPNEKSKHKFMVQTIFAP--PNTSDMEAVWKEAKPDELMDSKLRCVFEMPNENDKLNDMEPSKAV-------------PLNASKQDGPMP-KPHSVSLNDTETRKLMEECK---RLQGEMMKLSEENRHLR-DEGLRLR------KVAHSDKPGSTSTASFRDNVTSPLPSLLVVIAAIFIGFFLGKFIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A092-1", "uniprot_id": "D4A092_RAT", "id": "D4A092-1", "name": "Vesicle-associated membrane protein-associated protein A", "aln": "MASVSRAPAKPPQILVLDPPTDLKFKGPFTAVATAHLKLRNPSTRK-VCFKVKSTSPRRYCVRPNSGVIEPGCTVTVAAMLQ----PSCCGPSQEVKHKFMVQTVFAP--PDTSDLEAVWRGVNPGELMDSKLRCVFEAPTESDKL----------------------------------------------------------------------------EDGLRLR------KVAHPDKPGPSSCTSLKKGYTTPLPVVLLVIGAVFFGFFLGKLVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QY76-1", "uniprot_id": "VAPB_MOUSE", "id": "Q9QY76-1", "name": "Vesicle-associated membrane protein-associated protein B", "aln": "-------MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRN-VCFKVKTTVPRRYCVRPNSGVIDAGASLNVSVMLQ----PFDYDPNEKSKHKFMVQSMFAP--PDTSDMEAVWKEAKPEDLMDSKLRCVFELPAENAKPHDVEINKII-------------PTSASKTEAPAAAKSLTSPLDDTEVKKVMEECR---RLQGEVQRLREESRQLKEEDGLRVR------KAMPSNSPVAALAATGKEEGLSAR-LLALVVLFFIVGVIIGKIAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z269-1", "uniprot_id": "VAPB_RAT", "id": "Q9Z269-1", "name": "Vesicle-associated membrane protein-associated protein B", "aln": "-------MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRN-VCFKVKTTAPRRYCVRPNSGVIDAGASLNVSVMLQ----PFDYDPNEKSKHKFMVQSMFAP--PDTSDMEAVWKEAKPEDLMDSKLRCVFELPAENAKPHDVEINKIM-------------PTSASKTEAPVAAKPLTSPLDDAEVKKVMEECR---RLQGEVQRLREESRQLKEEDGLRAR------KALPSNSPMAALAASGKEEGLSAR-LLALVVLFFIVGVIIGKIAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95292-1", "uniprot_id": "VAPB_HUMAN", "id": "O95292-1", "name": "Vesicle-associated membrane protein-associated protein B/C", "aln": "-------MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRN-VCFKVKTTAPRRYCVRPNSGIIDAGASINVSVMLQ----PFDYDPNEKSKHKFMVQSMFAP--TDTSDMEAVWKEAKPEDLMDSKLRCVFELPAENDKPHDVEINKII-------------STTASKTETPIVSKSLSSSLDDTEVKKVMEECK---RLQGEVQRLREENKQFKEEDGLRMR------KTVQSNSPISALAPTGKEEGLSTR-LLALVVLFFIVGVIIGKIAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4N8-1", "uniprot_id": "Q9W4N8_DROME", "id": "Q9W4N8-1", "name": "", "aln": "-----MSKSLFDLPLTIEPEHELRFVGPFTRPVVTIMTLRNNSALP-LVFKIKTTAPKRYCVRPNIGKIIPFRSTQVEICLQ----PFVYDQQEKNKHKFMVQSVLAPMDADLSDLNKLWKDLEPEQLMDAKLKCVFEMPTAEANAENTSGGGAVGGGTGAAGGGSAGANTSSASAEALESKPKLSSEDKFKPSNLLETSESLDLLSGEIKALRECNIELR-RENLHLKDQITRFRSSPAVKQVNEPYAPVLAEKQIPVFYIAVAIAAAIVSLLLGKFFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VSD3-1", "uniprot_id": "Q9VSD3_DROME", "id": "Q9VSD3-1", "name": "", "aln": "------MSDNTESKLALDPCDVIVFEGPFNRSVSRKLVIKNTSKTQRMAFKMKTTTPKLFYVRPNIGVLGPEQKVSVDIFMQ----PILQEQIKK-RHKFLLLAAEVT--GDISDVQEFWKMQNPNETRETKIKCELVPSKEDDFRQAGGSAVIS------------------------------TDNKDGEVHFDAQEVS-------EPMAKLLKQVSMLEDEHMALT------------DQIDGLRDQAIGRTFFYMAAIVIIILSAVAGAYYGKTRL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6Q595-1", "uniprot_id": "SCS22_YEAST", "id": "Q6Q595-1", "name": "Vesicle-associated membrane protein-associated protein SCS22", "aln": "--------------MRIVP-EKLVFKAPLNKQSTEYIKLENDGEKR-VIFKVRTSAPTKYCVRPNVAIIGAHESVNVQIVFLGLPKSTADDEMDQKRDKFLIVTLPIP---------AAYQNVEDGELLSDWPNLEEQYKDDIVFKKIKIFHSVLP----------------------------------------------------------------------KRK------PSGNHDAESARAPSAGNGQSLSSRALLIITVIALLVGWIYY----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * : * .*:. : : * : **:::: * : **** . : . * : . .: :.**:: : . :: : : . . : : : . . ", "identical_positions": 14, "similar_positions": 38, "identity": "5.0%" }, { "cls_id": "homologset.agr.SGD:S000007235", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHW9-1", "uniprot_id": "D3ZHW9_RAT", "id": "D3ZHW9-1", "name": "26S proteasome complex subunit SEM1", "aln": "MS------EKKQ--------PVDLG--LLEEDDEFEEFPAEDWAGLDEDE-----DAHVWEDNWDDDNVEDDFSNQLRAELEKHGYKMETS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60897-1", "uniprot_id": "SEM1_MOUSE", "id": "P60897-1", "name": "26S proteasome complex subunit SEM1", "aln": "MS------EKKQ--------PVDLG--LLEEDDEFEEFPAEDWAGLDEDE-----DAHVWEDNWDDDNVEDDFSNQLRAELEKHGYKMETS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VM46-1", "uniprot_id": "SEM1_DROME", "id": "Q9VM46-1", "name": "Probable 26S proteasome complex subunit sem1", "aln": "MSA--PDKEKEKEKEETNNKSEDLG--LLEEDDEFEEFPAEDFRVGDDEE-----ELNVWEDNWDDDNVEDDFSQQLKAHLESK--KMET-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O94742-1", "uniprot_id": "SEM1_YEAST", "id": "O94742-1", "name": "26S proteasome complex subunit SEM1", "aln": "MSTDVAAAQAQSKIDLTKKKNEEINKKSLEEDDEFEDFPIDTWANGETIKSNAVTQTNIWEENWDDVEVDDDFTNELKAELDRY--KRENQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : :. ::. ********:** : : : : : ::**:**** :*:***:::*:*.*: * *. ", "identical_positions": 27, "similar_positions": 24, "identity": "29.67%" }, { "cls_id": "homologset.agr.SGD:S000007237", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYM7-1", "uniprot_id": "D3ZYM7_RAT", "id": "D3ZYM7-1", "name": "", "aln": "---MAASSRAQVLDLYRAMMRESKHFSAYNYRMYAVRRIRDAFRENKNVKDPVEIQALVNKAKRDLEIIRRQVLIGQLYSTDKLIIENQENPRT---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K215-1", "uniprot_id": "LYRM4_MOUSE", "id": "Q8K215-1", "name": "LYR motif-containing protein 4", "aln": "---MAASSRAQVLDLYRAMMRESKHFSAYNYRMYAVRRIRDAFRENKNVKDPVEIQALVNKAKRDLEIIRRQVHIGQLYSTDKLIIENQEKPRT---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HD34-1", "uniprot_id": "LYRM4_HUMAN", "id": "Q9HD34-1", "name": "LYR motif-containing protein 4", "aln": "---MAASSRAQVLSLYRAMLRESKRFSAYNYRTYAVRRIRDAFRENKNVKDPVEIQTLVNKAKRDLGVIRRQVHIGQLYSTDKLIIENRDMPRT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O46098-1", "uniprot_id": "LYRM4_DROME", "id": "O46098-1", "name": "LYR motif-containing protein 4 homolog", "aln": "-----MSTRRQAITLYRNLLRESEKLPSYNFRMYAARKIRDTFRANRSTRDFAEIDRQMAEGQQNLELIRRQVIIGHLYSADKLVIENKKTLKPSDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B8JLQ0-1", "uniprot_id": "LYRM4_DANRE", "id": "B8JLQ0-1", "name": "LYR motif-containing protein 4", "aln": "---MASCSRAQVISLYRMLMKESKKFPSYNYRTYALRRVKDGFRENLHVDNPRTLDLLINQARENLAVIKRQVSIGHLYSAQRTVVEKEPHL-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6Q560-1", "uniprot_id": "ISD11_YEAST", "id": "Q6Q560-1", "name": "Protein ISD11", "aln": "MPGFTAPTRRQVLSLYKEFIKNANQFNNYNFREYFLSKTRTTFRKNMNQQDPKVLMNLFKEAKNDLGVLKRQSVISQMYTFDRLVVEPLQGRKH---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *.: **: :::::::: **:* * : : ** * : : . :.:.:* :::** *.::*: :: ::* ", "identical_positions": 17, "similar_positions": 34, "identity": "17.53%" }, { "cls_id": "homologset.agr.SGD:S000007242", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZEH4-1", "uniprot_id": "D3ZEH4_RAT", "id": "D3ZEH4-1", "name": "Pseudouridine-5'-phosphatase", "aln": "--------------MAEAVPVPQLRPVTHLIFDLDGLLLNTEDLYTDVFQAICSRYGK-KYNWDVKSLVMGKKAPETTQIIVDFLKLPISKEQLLEESQERLQKVLHTAALMPGAEELIHHLRKNRLPFALATSSATLSFQTKTSRYKGFFSLFHHIVLGD-DPEVI--NSKPAPDIFLT----CAKRFSPPPNPEDCLVFEDSPNGVEAAVACGMQVVMVPHENLSSDLTTKATLVLSSLHEFK-PELFGLPAFDE--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D5U5-1", "uniprot_id": "HDHD1_MOUSE", "id": "Q9D5U5-1", "name": "Pseudouridine-5'-phosphatase", "aln": "--------------MAAAVPVPQFRPVTPLIFDLDGLILNTEDLYTDVFEEICNRYGK-KYNWDVKSLVMGKKALETAQTIVEFLNLPISKEELLKESQEKLQMVLHTAGFMPGAEELIHHLKKHRLPFALATSSETVTFQTKTSRHTGFFGLFHHIVLGD-DPEVK--NGKPGMDIFLT----CAKRFSPPPDPKDCLVFEDSPNGVEAAIHCGMQVVMVPHENLSADLTRKATLVLSSLHDFK-PELFGLPAFTE--------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08623-1", "uniprot_id": "HDHD1_HUMAN", "id": "Q08623-1", "name": "Pseudouridine-5'-phosphatase", "aln": "--------------MAAPP-----QPVTHLIFDMDGLLLDTERLYSVVFQEICNRYDK-KYSWDVKSLVMGKKALEAAQIIIDVLQLPMSKEELVEESQTKLKEVFPTAALMPGAEKLIIHLRKHGIPFALATSSGSASFDMKTSRHKEFFSLFSHIVLGD-DPEVQ--HGKPDPDIFLA----CAKRFSPPPAMEKCLVFEDAPNGVEAALAAGMQVVMVPDGNLSRDLTTKATLVLNSLQDFQ-PELFGLPSYE---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N669-1", "uniprot_id": "A0A8M1N669_DANRE", "id": "A0A8M1N669-1", "name": "Pseudouridine-5'-phosphatase", "aln": "---------------------MSYKPVTHVLFDMDGLLLDTERLYTVSFQEVCDRFNK-QYTWEVKSSVMGKKALDAARIIRDKIGLPMTPEELLEETRKIQERLFPTTSLLPGVEKLVNHLHKHGIPIAVGTSSAGLTFEMKTSRHKEFFSLFSHIVLGD-DPDVK--NGKPLPDTFLV----CAKRFSPPANPKQCLVFEDAPNGVKAGLAAGMQVVMIPDDNLDRSLTQEATLLLRSMEDFR-PELFGLPAYA---------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94529-1", "uniprot_id": "GS1_DROME", "id": "Q94529-1", "name": "Probable pseudouridine-5'-phosphatase", "aln": "--------------MANKV----LRKVTHCVFDMDGLLLDTERLYTVATEMILEPYGK-TYPFEIKEQVMGLQTEPLARFMVEHYELPMSWEEYARQQRANTEILMRNAQLMPGAERLLRHLHANKVPFCLATSSGADMVELKTAQHRELFSLFNHKVCGSSDKEVV--NGKPAPDIFLV----AAGRFGVPPKPSDCLVFEDSPNGVTAANSAGMQVVMVPDPRLSQEKTSHATQVLASLADFK-PEQFGLPAFTD--------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQ04-1", "uniprot_id": "Q9VQ04_DROME", "id": "Q9VQ04-1", "name": "", "aln": "--------------MPTKK---CYCPVTHVIFDCDGTLIDSEGIYLKTVQDLLAKYGK-TYTKVDQTQHMGMPVGTFSQHIVKDLKLPLSPAEFQKEFEAAVDKSMGSVALLPGVRDLILHLHEYRIPFCIATSSFRKLFKVKAESFKDIFLAFHHVVCGD-DPALGPGRGKPYPDIYLL----AASRFNPPADPKKCLIFEDAPVGLIGGKAAGSQVIFIPTDNVSKQQKKGATMVLKSMADFK-PELFGLPPFDTCSKFEFG-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q86ZR7-1", "uniprot_id": "YKD3A_YEAST", "id": "Q86ZR7-1", "name": "Probable pseudouridine-5'-phosphatase YKL033W-A", "aln": "--------------MTHPV------AVKACLFDMDGLLINTEDIYTETLNETLAEFGKGPLTWDVKIKLQGLPGPEAGKRVIEHYKLPITLDEYDERNVALQSLKWGTCEFLPGALNLLKYLKLKNIPIALCTSSNKTKFRGKTSHLEEGFDLFDTIVTGD-DPRIAKGRGKPFPDIWQLGLKELNEKFHTDIKPDECIVFEDGIPGVKSAKAFGAHVIWVPHPEAHAVLGDTEALLAGKGELLSSLEKLEMSKYGL--------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VQ01-1", "uniprot_id": "Q9VQ01_DROME", "id": "Q9VQ01-1", "name": "", "aln": "MCSACCKSCKAPPGCSLCPPMCCSPGISYCIFDLESAVFDTRHVYKRAVIELAASYNK-IIPEAVLIKSGPMETAEMAELICRKCDLPVSWESFRFQLNERTSDLIANPTLMPGVERLVTHLGRCCMGLGLITSCSESMYCTKIRDREDFFQNFSSVICAD-DADLK--APKPEPDVYLI----AMRRLG-DAGPDCTLVFDGTPKGVQAATDARLPVVMLAEKDLPCCWSELATLRLETLEEFD-PAEFNMPPYSCTEPPPKKPKASSHRSSQKSAGSQRGSAALKKAAADSEADEGEEEEGEGQEVA----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQ02-1", "uniprot_id": "Q9VQ02_DROME", "id": "Q9VQ02-1", "name": "Pseudouridine-5'-phosphatase", "aln": "MCTFGCRTCKSQPDCEGCSPKCCSPCISYCIFDLESAVFDTRHVYRKALKELVRCYDK-RIPDILHVQSGPMTISEMSELFCRKLDIPMSWESFRYELNERTSHLIANPPFMDGIERLVPHLRNSCMELGLITSSNEANYCSKIRGREDFFENFSTVVCAD-DPELR--APKPEPDVYLI----AMSRLG-DAGPDCTLVFDGTPKGVQAASDARLPVIMLAEKDLPCCWSELAALRFEYLDDFE-PEMYNLPPF--TDPAPKR--RSSRRRTRYSQRLTVIRARAAEAAAAEEAEAEEEEPAEPPPPAALPSILNLRE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :** :. ::::. :* :.* . . :*:: . . . . :: * *: :* : : : **. * * * : .. * : ** * : :: . ::*:. *: .. *: :. : : :. : ", "identical_positions": 20, "similar_positions": 53, "identity": "6.27%" }, { "cls_id": "homologset.agr.SGD:S000007243", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZY71-1", "uniprot_id": "D3ZY71_RAT", "id": "D3ZY71-1", "name": "", "aln": "-----MNSVGEACTDMKREYDQCFNRWFAEKFLKGDGSGDPCTDLFKRYQQCVQKAIKEK----EIPIEGLE--FMGHGKEKPENSS----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D8Z2-1", "uniprot_id": "TRIA1_MOUSE", "id": "Q9D8Z2-1", "name": "TP53-regulated inhibitor of apoptosis 1", "aln": "-----MNSVGEACTDMKREYDQCFNRWFAEKFLKGDGSGDPCTDLFKRYQQCVQKAIKEK----EIPIEGLE--FMGHGKEKPENSS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43715-1", "uniprot_id": "TRIA1_HUMAN", "id": "O43715-1", "name": "TP53-regulated inhibitor of apoptosis 1", "aln": "-----MNSVGEACTDMKREYDQCFNRWFAEKFLKGDSSGDPCTDLFKRYQQCVQKAIKEK----EIPIEGLE--FMGHGKEKPENSS----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1ZAX2-1", "uniprot_id": "A1ZAX2_DROME", "id": "A1ZAX2-1", "name": "TP53-regulated inhibitor of apoptosis 1", "aln": "-----MSSVGEDCNELKQQYDACFNSWFSERFLKGQMDDSACAPIFRVYQECVKRAIKEK----KIDLQEIDPIFETGLEENNANRSDAKQQQAGES", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O60200-1", "uniprot_id": "MDM35_YEAST", "id": "O60200-1", "name": "Mitochondrial distribution and morphology protein 35", "aln": "MGNIMSASFAPECTDLKTKYDSCFNEWYSEKFLKGKSVENECSKQWYAYTTCVNAALVKQGIKPALDEAREEAPFENGGKLKEVDK-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. *.::* :** *** *::*:****. . *: : * **: *: :: : : * : : : ", "identical_positions": 20, "similar_positions": 22, "identity": "20.62%" }, { "cls_id": "homologset.agr.SGD:S000007245", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q49B96-1", "uniprot_id": "COX19_HUMAN", "id": "Q49B96-1", "name": "Cytochrome c oxidase assembly protein COX19", "aln": "-----MSTAMNFGTKSFQ---PRPPDKGSFP----------LDHLG-ECKSFKEKFMKCLHNNNFENAL-CRKESKEYLECRMERKLMLQEPLEKLGFGDLTSG------KSEAKK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K0C8-1", "uniprot_id": "COX19_MOUSE", "id": "Q8K0C8-1", "name": "Cytochrome c oxidase assembly protein COX19", "aln": "-----MSTAMNFGTKSFQ---PRPPDKGSFP----------LDHFG-ECKSFKEKFMRCLRDKNYENAL-CRNESKEYLMCRMQRQLMAPEPLEKLGFRDLMEG------KPEAKDEC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZIS5-1", "uniprot_id": "D3ZIS5_RAT", "id": "D3ZIS5-1", "name": "Cytochrome c oxidase assembly protein COX19", "aln": "MLGECFTSEPHLQPRGFPVTIPKSTVDLSFGKPKRVKEKNNWERVGGECKSFKEKFMKCLRDKNYENAL-CRNESKEYLMCRMQRQLMAPEPLEKLGFRDIMEE------KPEAKDKC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3E731-1", "uniprot_id": "COX19_YEAST", "id": "Q3E731-1", "name": "Cytochrome c oxidase assembly protein COX19", "aln": "-----MSGNPGSSLSALR---PTPPERGSFP----------LDHDG-ECTKYMQEYLKCMQLVQNENAMNCRLLAKDYLRCRMDHQLMDYDEWSHLGLPEDAPGNNGKTIKDATDNK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "E1JGR4-1", "uniprot_id": "E1JGR4_DROME", "id": "E1JGR4-1", "name": "CHCH domain-containing protein", "aln": "-----MTSQIYS-QKKFV---PTPPEKGSFP----------LDHEG-LCKKQFLLYASCLRKN-AQDTSQCRQDAQNYLACRMDNNLMEKTEWSKLGFHDQSTKTDQK--EPEVQKQ-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : * .. ** :: * *.. : *:: ::: ** :::** ***:.:** .:**: : : ... ", "identical_positions": 17, "similar_positions": 29, "identity": "14.41%" }, { "cls_id": "homologset.agr.SGD:S000007246", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K003-1", "uniprot_id": "TMA7_MOUSE", "id": "Q8K003-1", "name": "Translation machinery-associated protein 7", "aln": "MSGREGGKKKPLKQPKKQAKEMDEEDKAFKQKQKEEQKKLEELKAKAAGKGPLATGGIKKSGKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZZW2-1", "uniprot_id": "D3ZZW2_RAT", "id": "D3ZZW2-1", "name": "", "aln": "MSGREGGKKKPLKQPKKQAKEMDEEDKAFKQKQKEEQKKLEELKAKAAGKGPLATGGIKKSGKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2S6-1", "uniprot_id": "TMA7_HUMAN", "id": "Q9Y2S6-1", "name": "Translation machinery-associated protein 7", "aln": "MSGREGGKKKPLKQPKKQAKEMDEEDKAFKQKQKEEQKKLEELKAKAAGKGPLATGGIKKSGKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LYW7-1", "uniprot_id": "A0ABK0LYW7_RAT", "id": "A0ABK0LYW7-1", "name": "Coiled-coil domain-containing protein 72", "aln": "MSGREGGKKKPLKQPKKQAKEMDEEDKAFKQKQKEEQKKLEELKAKAEGKGPLATGGIKKSGKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A024R1R8-1", "uniprot_id": "TMA7B_HUMAN", "id": "A0A024R1R8-1", "name": "Translation machinery-associated protein 7B", "aln": "MSSHEGGKKKALKQPKKQAKEMDEEEKAFKQKQKEEQKKLEVLKAKVVGKGPLATGGIKKSGKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q05AK9-1", "uniprot_id": "TMA7_DANRE", "id": "Q05AK9-1", "name": "Translation machinery-associated protein 7", "aln": "MSGREGGKKKPLKAPKKQSKEMDEDEMAFKQKQKEDQKAMEQLKAKAAGKGPLTGGGIKKSGKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XZS3-1", "uniprot_id": "TMA7_DROME", "id": "Q9XZS3-1", "name": "Translation machinery-associated protein 7 homolog", "aln": "MSGREGGKKKPLKAPKKDSKDLDEDDMAFKQKQKEQQKALEAAKANASKKGPLVGGGIKKSGKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6IHK7-1", "uniprot_id": "Q6IHK7_DROME", "id": "Q6IHK7-1", "name": "Translation machinery-associated protein 7 homolog", "aln": "MAGREGGKKKPLKAPKKDSKNLDEEDMAFKQKQKEQQKAMEAAKAGASKKGPLLGGGIKKSGKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3E764-1", "uniprot_id": "TMA7_YEAST", "id": "Q3E764-1", "name": "Translation machinery-associated protein 7", "aln": "MSSRQGGKMKPLKQKKKQQQDLDPEDIAFKEKQKADAAAKKALMANMKSGKPLVGGGIKKSGKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.::*** *.** **: :::* :: ***:*** : : * ** *********", "identical_positions": 28, "similar_positions": 14, "identity": "43.75%" }, { "cls_id": "homologset.agr.SGD:S000007251", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BZL1-1", "uniprot_id": "UBL5_HUMAN", "id": "Q9BZL1-1", "name": "Ubiquitin-like protein 5", "aln": "MIEVVCNDRLGKKVRVKCNTDDTIGDLKKLIAAQTGTRWNKIVLKKWYTIFKDHVSLGDYEIHDGMNLELYYQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9EPV8-1", "uniprot_id": "UBL5_MOUSE", "id": "Q9EPV8-1", "name": "Ubiquitin-like protein 5", "aln": "MIEVVCNDRLGKKVRVKCNTDDTIGDLKKLIAAQTGTRWNKIVLKKWYTIFKDHVSLGDYEIHDGMNLELYYQ---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1Y7VKT9-1", "uniprot_id": "A0A1Y7VKT9_MOUSE", "id": "A0A1Y7VKT9-1", "name": "Ubiquitin-like protein 5", "aln": "MIEVVCNDRLGKKVRVKCNTDDTIGDLKKLIAAQTGTRWNKIILKKWYTIYKDHVSLGDYEIHDGMNLELYYQ---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7SXF2-1", "uniprot_id": "UBL5_DANRE", "id": "Q7SXF2-1", "name": "Ubiquitin-like protein 5", "aln": "MIEVVCNDRLGKKVRVKCNQEDTIGDLKKLIAAQTGTRWEKIVLKKWYTIFKNHVSLGDYEIHDGMNLELYYL---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V998-1", "uniprot_id": "UBL5_DROME", "id": "Q9V998-1", "name": "Ubiquitin-like protein 5", "aln": "MIEITCNDRLGKKVRVKCNPDDTIGDLKKLIAAQTGTKHEKIVLKKWYTIFKDPIRLSDYEIHDGMNLELYYQ---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6Q546-1", "uniprot_id": "HUB1_YEAST", "id": "Q6Q546-1", "name": "Ubiquitin-like modifier HUB1", "aln": "MIEVVVNDRLGKKVRVKCLAEDSVGDFKKVLSLQIGTQPNKIVLQKGGSVLKDHISLEDYEVHDQTNLELYYL---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0ABK0LJN3-1", "uniprot_id": "A0ABK0LJN3_RAT", "id": "A0ABK0LJN3-1", "name": "Ubiquitin-like protein 5", "aln": "MIEVVCNDRLGKKVRVKCNTDDTIGDLKKLIAAQTGTRWNKIVLKKCFS-LKAIYPVGTRFLKTTCLWETMRSTTG", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:. ************ :*::**:**::: * **: :**:*:* : * : :: * ", "identical_positions": 29, "similar_positions": 17, "identity": "38.16%" }, { "cls_id": "homologset.agr.SGD:S000007253", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60869-1", "uniprot_id": "EDF1_HUMAN", "id": "O60869-1", "name": "Endothelial differentiation-related factor 1", "aln": "---------------------------------------------------MAESDWDTVT---------------VLRKK---GPTAAQAKSKQAILAAQRRGEDVETSK-KWAAGQNKQHSITKNTAKLDRETEELHHDRVTLEVGKVIQQGRQSKGLTQKDLATKINEKPQVIADYESGRAIPNNQVLGKIERAIGLKLRGKDIGKPIEKGPRAK------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JMG1-1", "uniprot_id": "EDF1_MOUSE", "id": "Q9JMG1-1", "name": "Endothelial differentiation-related factor 1", "aln": "---------------------------------------------------MAESDWDTVT---------------VLRKK---GPTAAQAKSKQAILAAQRRGEDVETSK-KWAAGQNKQHSITKNTAKLDRETEELHHDRVTLEVGKVIQRGRQSKGLTQKDLATKINEKPQVIADYESGRAIPNNQVLGKIERAIGLKLRGKDIGKPIEKGPKAK------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L496-1", "uniprot_id": "A0ABK0L496_RAT", "id": "A0ABK0L496-1", "name": "Endothelial differentiation-related factor 1", "aln": "MWRHPKNVGTQVSTCKARVCCGIACLMVWCGGTPGNCQEQRLGSQEIFLTCRHSSGWHEISGIVPSHLLPATVGRFRFRPRKMLGLACQSGVHLKSFPCADCKPHSVPLTLPAGAAGQNKQHSITKNTAKLDRETEELHHDRVTLEVGKVIQRGRQSKGLTQKDLATKINEKPQVIADYESGRAIPNNQVLGKIERAIGLKLRGKDIGKPIEKGPKAK------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PBY3-1", "uniprot_id": "EDF1_DANRE", "id": "Q6PBY3-1", "name": "Endothelial differentiation-related factor 1 homolog", "aln": "---------------------------------------------------MAECDWDTVT---------------VLRKK---GSAAQSK-SKQAVTAAQRKGEAVETSK-KWAAGQNKQHVVTKNTAKLDRETEELSHQRVPLEVGKVIQQGRQNKGLTQKDLATKINEKPQIIAEYECGKAIPNNQVMGKIERAIGLKLRGKDIGLPLEACSKK-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PFR6-1", "uniprot_id": "M9PFR6_DROME", "id": "M9PFR6-1", "name": "", "aln": "-----------------------------------------------------MSDWDSVT---------------VLRKK---APKSSTLKTESAVNQARRQGVAVDTQQ-KYGAGTNKQHVTTKNTAKLDRETEELRHDKIPLDVGKLIQQGRQSKGLSQKDLATKICEKQQVVTDYEAGRGIPNNLILGKMERVLGIKLRGKERGQPIAPPGKKXNDAAASAASGAPHTVTSGRSARQQNHQHTDSGGWSTVSGRRK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O14467-1", "uniprot_id": "MBF1_YEAST", "id": "O14467-1", "name": "Multiprotein-bridging factor 1", "aln": "-----------------------------------------------------MSDWDTNTIIG-----------SRARAGGS-GPRANVARSQGQINAARRQGLVVSVDK-KYGSTNTRGDNEGQRLTKVDRETDIVKPKKLDPNVGRAISRARTDKKMSQKDLATKINEKPTVVNDYEAARAIPNQQVLSKLERALGVKLRGNNIGSPLGAPKKK-------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..*. : * . . . * : * .: .: . :. :*:****: : .:: :**: *.:.* .* ::******** ** :: :**..:.***: ::.*:**.:*:****:: * *: : ", "identical_positions": 39, "similar_positions": 49, "identity": "15.0%" }, { "cls_id": "homologset.agr.SGD:S000007256", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WV98-1", "uniprot_id": "TIM9_MOUSE", "id": "Q9WV98-1", "name": "Mitochondrial import inner membrane translocase subunit Tim9", "aln": "-------MAAQIPESDQIKQFKEFLGTYNKLTETCFLDCVKDFTTREVKPEEVTCSEHCLQKYLKMTQRISVRFQ-------EYHIQQNE-------------ALAAKAGLLGQPR-------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WV97-1", "uniprot_id": "TIM9_RAT", "id": "Q9WV97-1", "name": "Mitochondrial import inner membrane translocase subunit Tim9", "aln": "-------MAAQIPESDQIKQFKEFLGTYNKLTETCFLDCVKDFTTREVKPEEVTCSEHCLQKYLKMTQRISMRFQ-------EYHIQQNE-------------ALAAKAGLLGQPR-------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5J7-1", "uniprot_id": "TIM9_HUMAN", "id": "Q9Y5J7-1", "name": "Mitochondrial import inner membrane translocase subunit Tim9", "aln": "-------MAAQIPESDQIKQFKEFLGTYNKLTETCFLDCVKDFTTREVKPEETTCSEHCLQKYLKMTQRISMRFQ-------EYHIQQNE-------------ALAAKAGLLGQPR-------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W762-1", "uniprot_id": "TIM9_DANRE", "id": "Q9W762-1", "name": "Mitochondrial import inner membrane translocase subunit Tim9", "aln": "-------MAAQVTESDQIKQFKEFLGTYNKLTENCFMDCVKDFTTREVKPEETTCSESCLQKYLKMTQRISMRFQ-------EYHIQQNE-------------RWPQKPDY------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYD7-1", "uniprot_id": "TIM9_DROME", "id": "Q9VYD7-1", "name": "Mitochondrial import inner membrane translocase subunit Tim9", "aln": "MAKTPENIAIDQLDKDQIKTFSDFLMSYNKLSETCFTDCIRDFTTRDVKDSEEKCSLNCMEKYLKMNQRVSQRFQ-------EFQVIAHEN----------ALAMAQKTGKL-----------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O74700-1", "uniprot_id": "TIM9_YEAST", "id": "O74700-1", "name": "Mitochondrial import inner membrane translocase subunit TIM9", "aln": "MDALNSKEQQEFQKVVEQKQMKDFMRLYSNLVERCFTDCVNDFTTSKLTNKEQTCIMKCSEKFLKHSERVGQRFQ-------EQNA-----------------ALGQGLGR------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9R1B1-1", "uniprot_id": "T10B_RAT", "id": "Q9R1B1-1", "name": "Mitochondrial import inner membrane translocase subunit Tim10 B", "aln": "-------ME---HQQQQLRNLRDFLLVYNRMTELCFQRCVPSLHHRALDAEEEACLHSCAGKLIHSNHRLMAAYVHLMPALVQRRMADYE-------------AASAVPGVPAE-----------------------------QPRDSP------------SGS-------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV96-1", "uniprot_id": "T10B_MOUSE", "id": "Q9WV96-1", "name": "Mitochondrial import inner membrane translocase subunit Tim10 B", "aln": "-------ME---QQQQQLRNLRDFLLVYNRMTELCFQRCVPSLHHRALDAEEEACLHSCAGKLIHSNHRLMAAYVHLMPALVQRRIADYE-------------AASAAPGIPAE-----------------------------QTRDSP------------SGS-------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5J6-1", "uniprot_id": "T10B_HUMAN", "id": "Q9Y5J6-1", "name": "Mitochondrial import inner membrane translocase subunit Tim10 B", "aln": "-------MERQQQQQQQLRNLRDFLLVYNRMTELCFQRCVPSLHHRALDAEEEACLHSCAGKLIHSNHRLMAAYVQLMPALVQRRIADYE-------------AASAVPGVAAE-----------------------------QPGVSP------------SGS-------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q568N4-1", "uniprot_id": "T10B_DANRE", "id": "Q568N4-1", "name": "Mitochondrial import inner membrane translocase subunit Tim10 B", "aln": "-------MD----PQGQLRNLRDFLLVYNRMTEICFHRCSSNFNYRNLTMDEERCVDSCAGKLIRTNHRLMGTYVQLMPAMVQKRMQEMESKAAEMAKAEAEAAAKAGTSVPDNPSSAITNASMMSPSIQDIPNTSSTAPNGFQILSSPDNTSDIKTSSMTNGSAFGETNLHVITNDAKTFTNQSLDELITPSPVNTSVPETPTAGGAGQTPS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y0V3-1", "uniprot_id": "T10B_DROME", "id": "Q9Y0V3-1", "name": "Mitochondrial import inner membrane translocase subunit Tim10B", "aln": "-------------MDSNLRNLKDFFTLYNKVTELCFSRCVDNLSQRDLGGHEDLCVDRCVTKFARFNQNMMKVYVDVQTTINAKRMEEMEEN-----------ARKAEQQQREQEKE--------------------------RLKEAAATAVLTPVQPPVAGNLSM----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :*: *..: * ** * .: : * * * * : ...: : . ", "identical_positions": 10, "similar_positions": 18, "identity": "4.69%" }, { "cls_id": "homologset.agr.SGD:S000007260", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05503-1", "uniprot_id": "COX1_RAT", "id": "P05503-1", "name": "Cytochrome c oxidase subunit 1", "aln": "MLVNRWLFSTNHKDIGTLYLLFGAWAGMVGTALSILIRAELGQPGA--LLGDDQIYNVIVTAHAFVMIFFMVMPMMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHVVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGLDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMLWALGFIFLFTVGGLTGIVLSNSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMAGFVHWFPLFSGYTLNDTWAKAHFAIMFVGVNMTFFPQHFLGLAGMPRRYSDYPDAYTTWNTVSSMGSFISLTAVLVMIFMIWEAFAS-------KREVLSISY---------------SSTNLEWLHGCPPPYHTFEEPSYVKVK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00397-1", "uniprot_id": "COX1_MOUSE", "id": "P00397-1", "name": "Cytochrome c oxidase subunit 1", "aln": "MFINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSILIRAELGQPGA--LLGDDQIYNVIVTAHAFVMIFFMVMPMMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHVVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGLDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMLWALGFIFLFTVGGLTGIVLSNSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMAGFVHWFPLFSGFTLDDTWAKAHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTTWNTVSSMGSFISLTAVLIMIFMIWEAFAS-------KREVMSVSY---------------ASTNLEWLHGCPPPYHTFEEPTYVKVK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00395-1", "uniprot_id": "COX1_HUMAN", "id": "P00395-1", "name": "Cytochrome c oxidase subunit 1", "aln": "MFADRWLFSTNHKDIGTLYLLFGAWAGVLGTALSLLIRAELGQPGN--LLGNDHIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSLLLLLASAMVEAGAGTGWTVYPPLAGNYSHPGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGSNMKWSAAVLWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFIHWFPLFSGYTLDQTYAKIHFTIMFIGVNLTFFPQHFLGLSGMPRRYSDYPDAYTTWNILSSVGSFISLTAVMLMIFMIWEAFAS-------KRKVLMVEE---------------PSMNLEWLYGCPPPYHTFEEPVYMKS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9MIY8-1", "uniprot_id": "COX1_DANRE", "id": "Q9MIY8-1", "name": "Cytochrome c oxidase subunit 1", "aln": "MTITRWFFSTNHKDIGTLYLVFGAWAGMVGTALSLLIRAELSQPGA--LLGDDQIYNVIVTAHAFVMIFFMVMPILIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSGVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTTINMKPPTISQYQTPLFVWAVLVTAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHVVAYYAGKKEPFGYMGMVWAMMAIGLLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGAIKWETPMLWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMAGFVHWFPLFTGYTLNSVWTKIHFGVMFIGVNLTFFPQHFLGLAGMPRRYSDYPDAYALWNTVSSIGSLISLVAVIMFLFILWEAFTA-------KREVLSVEL---------------TATNVEWLHGCPPPYHTFEEPAFVQIQSN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P00399-1", "uniprot_id": "COX1_DROME", "id": "P00399-1", "name": "Cytochrome c oxidase subunit 1", "aln": "--SRQWLFSTNHKDIGTLYFIFGAWAGMVGTSLSILIRAELGHPGA--LIGDDQIYNVIVTAHAFIMIFFMVMPIMIGGFGNWLVPLMLGAPDMAFPRMNNMSFWLLPPALSLLLVSSMVENGAGTGWTVYPPLSAGIAHGGASVDLAIFSLHLAGISSILGAVNFITTVINMRSTGISLDRMPLFVWSVVITALLLLLSLPVLAGAITMLLTDRNLNTSFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIISQESGKKETFGSLGMIYAMLAIGLLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAVPTGIKIFSWLATLHGTQLSYSPAILWALGFVFLFTVGGLTGVVLANSSVDIILHDTYYVVAHFHYVLSMGAVFAIMAGFIHWYPLFTGLTLNNKWLKSHFIIMFIGVNLTFFPQHFLGLAGMPRRYSDYPDAYTTWNIVSTIGSTISLLGILFFFFIIWESLVS-------QRQVIYPIQ---------------LNSSIEWYQNTPPAEHSYSELPLLTN---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00401-1", "uniprot_id": "COX1_YEAST", "id": "P00401-1", "name": "Cytochrome c oxidase subunit 1", "aln": "-MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVVGHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVESGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFGHPEVYILIIPGFGIISHVVSTYS-KKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGLDADTRAYFTSATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVALANASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNYNEKLAQIQFWLIFIGANVIFFPMHFLGINGMPRRIPDYPDAFAGWNYVASIGSFIATLSLFLFIYILYDQLVNGLNNKVNNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPAVHSFNTPAVQS----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*::*** ***..**:::. ::*: **::*::** **. ** * *:.:::**:*..**.:****:*** :******:*:***:**.* ****:**::**:** .: *:.*: ** ************:. :* *.****:**:***:.:**:***:***.* :**:. :: : *****::.:**.*********:..***** ***:**:**: :********:***************:****:***::: : ** ** :.*::** :**:***:**:***: **:*.**************:***:*:******:** : ..:*:*:.*:****:*****:.*:*:*:*: :*******.**********:*:::.*: :* * : * . :. : :* ::*:*.*: *** ****: ***** .*****:: ** ::::** *: .::.::::::: :. ::.*: .:*: **. *::. ", "identical_positions": 267, "similar_positions": 162, "identity": "49.44%" }, { "cls_id": "homologset.agr.SGD:S000007264", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05503-1", "uniprot_id": "COX1_RAT", "id": "P05503-1", "name": "Cytochrome c oxidase subunit 1", "aln": "MLVNRWLFSTNHKDIGTLYLLFGAWAGMVGTALSILIRAELGQPGA--LLGDDQIYNVIVTAHAFVMIFFMVMPMMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHVVTYYSGKKEPFGYMG-MVWAMMSIGFLGFIVWAHHMFTVGLDVDTRAYFTSATMIIAIP--TGVKVFSWLATLHGG------------NIKWSPAMLWALGFIFLFTVGG------------------LTGIVLSNSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMAGFVHWFPLFSGYTLNDTWAKAHFAIMFVGVNMTFFPQHFLGLAGMPRRYSD--YPDAYTTWNTVSSMGSFISLTAVLVMIFMIWEAFASKREVLSISYSSTNLEWLHGCPPPYHTFEEPSYVKVK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00397-1", "uniprot_id": "COX1_MOUSE", "id": "P00397-1", "name": "Cytochrome c oxidase subunit 1", "aln": "MFINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSILIRAELGQPGA--LLGDDQIYNVIVTAHAFVMIFFMVMPMMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHVVTYYSGKKEPFGYMG-MVWAMMSIGFLGFIVWAHHMFTVGLDVDTRAYFTSATMIIAIP--TGVKVFSWLATLHGG------------NIKWSPAMLWALGFIFLFTVGG------------------LTGIVLSNSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMAGFVHWFPLFSGFTLDDTWAKAHFAIMFVGVNMTFFPQHFLGLSGMPRRYSD--YPDAYTTWNTVSSMGSFISLTAVLIMIFMIWEAFASKREVMSVSYASTNLEWLHGCPPPYHTFEEPTYVKVK------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00395-1", "uniprot_id": "COX1_HUMAN", "id": "P00395-1", "name": "Cytochrome c oxidase subunit 1", "aln": "MFADRWLFSTNHKDIGTLYLLFGAWAGVLGTALSLLIRAELGQPGN--LLGNDHIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSLLLLLASAMVEAGAGTGWTVYPPLAGNYSHPGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMG-MVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIP--TGVKVFSWLATLHGS------------NMKWSAAVLWALGFIFLFTVGG------------------LTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFIHWFPLFSGYTLDQTYAKIHFTIMFIGVNLTFFPQHFLGLSGMPRRYSD--YPDAYTTWNILSSVGSFISLTAVMLMIFMIWEAFASKRKVLMVEEPSMNLEWLYGCPPPYHTFEEPVYMKS-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9MIY8-1", "uniprot_id": "COX1_DANRE", "id": "Q9MIY8-1", "name": "Cytochrome c oxidase subunit 1", "aln": "MTITRWFFSTNHKDIGTLYLVFGAWAGMVGTALSLLIRAELSQPGA--LLGDDQIYNVIVTAHAFVMIFFMVMPILIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSGVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTTINMKPPTISQYQTPLFVWAVLVTAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHVVAYYAGKKEPFGYMG-MVWAMMAIGLLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIP--TGVKVFSWLATLHGG------------AIKWETPMLWALGFIFLFTVGG------------------LTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMAGFVHWFPLFTGYTLNSVWTKIHFGVMFIGVNLTFFPQHFLGLAGMPRRYSD--YPDAYALWNTVSSIGSLISLVAVIMFLFILWEAFTAKREVLSVELTATNVEWLHGCPPPYHTFEEPAFVQIQSN----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P00399-1", "uniprot_id": "COX1_DROME", "id": "P00399-1", "name": "Cytochrome c oxidase subunit 1", "aln": "--SRQWLFSTNHKDIGTLYFIFGAWAGMVGTSLSILIRAELGHPGA--LIGDDQIYNVIVTAHAFIMIFFMVMPIMIGGFGNWLVPLMLGAPDMAFPRMNNMSFWLLPPALSLLLVSSMVENGAGTGWTVYPPLSAGIAHGGASVDLAIFSLHLAGISSILGAVNFITTVINMRSTGISLDRMPLFVWSVVITALLLLLSLPVLAGAITMLLTDRNLNTSFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIISQESGKKETFGSLG-MIYAMLAIGLLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAVP--TGIKIFSWLATLHGT------------QLSYSPAILWALGFVFLFTVGG------------------LTGVVLANSSVDIILHDTYYVVAHFHYVLSMGAVFAIMAGFIHWYPLFTGLTLNNKWLKSHFIIMFIGVNLTFFPQHFLGLAGMPRRYSD--YPDAYTTWNIVSTIGSTISLLGILFFFFIIWESLVSQRQVIYPIQLNSSIEWYQNTPPAEHSYSELPLLTN-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P03878-1", "uniprot_id": "SCE2_YEAST", "id": "P03878-1", "name": "Intron-encoded DNA endonuclease aI4", "aln": "-MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVVGHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVESGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFGQTVATIIMLMMYNDMHFSKCWKLLKKWITNIMSTLFKALFVKMFMSYNNQQDKMMNNTMLKKDNIKRSSETTRKMLNNSMNKKFNQWLAGLIDGDGYFGIVSKKYVSLEITVALEDEMALKEIQNKFGGSIKLRSGVKAIRYRLTNKTGMIKLINAVNGNIRNTKRLVQFNKVCILLGIDFIYPIKLTKDNSWFVGFFDADGTINYSFKNNHPQLTISVTNKYLQDVQEYKNILGGNIYFDKSQNGYYKWSIQSKDMVLNFINDYIKMNPSRTTKMNKLYLSKEFYNLKELKAYNKSSDSMQYKAWLNFENKWKNK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*::*** ***..**:::. ::*: **::*::** **. ** * *:.:::**:*..**.:****:*** :******:*:***:**.* ****:**::**:** .: *:.*: ** ************:. :* *.****:**:***:.:**:***:***.* :**:. :: : *****::.:**.*********:..***** ***:**:**: :********:*******:. . *::* :. : . ** . :. :. *:: ::.: .:*:. : . . :* * : . *. .*** * . :. .: :.: : . * **:: .::: :::* :* . : : :* * : : . * * . : * . :.::. ::: .: . .. * * :: * : .: : : : .:: : : .:: . .: . : ", "identical_positions": 163, "similar_positions": 169, "identity": "29.26%" }, { "cls_id": "homologset.agr.SGD:S000007265", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05503-1", "uniprot_id": "COX1_RAT", "id": "P05503-1", "name": "Cytochrome c oxidase subunit 1", "aln": "MLVNRWLFSTNHKDIGTLYLLFGAWAGMVGTALSILIRAELGQPGA--LLGDDQIYNVIVTAHAFVMIFFMVMPMMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHVVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGLDVDTRAYFTSATMIIAIPTGVKVFSWLATLHG---------------GNIKWSPAMLWALGFIFLFTVGGLTG-------------IVLSNSSLDIVLH----------DTYY-VVAHFH-------YVLS------------------------MGAVFAIMAGFVHWFPLFSGYTLNDTWAKAHFAIMFVGVN------MTFFP--------QHFLGLAG----MPRRYSDYPDAYTTWNTVSSMGSFIS------------------LTAVLVMIFMIWEAFASKREVLSISYSSTNLEWLHG------CPPPYHTFEEPSYVKVK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00397-1", "uniprot_id": "COX1_MOUSE", "id": "P00397-1", "name": "Cytochrome c oxidase subunit 1", "aln": "MFINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSILIRAELGQPGA--LLGDDQIYNVIVTAHAFVMIFFMVMPMMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHVVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGLDVDTRAYFTSATMIIAIPTGVKVFSWLATLHG---------------GNIKWSPAMLWALGFIFLFTVGGLTG-------------IVLSNSSLDIVLH----------DTYY-VVAHFH-------YVLS------------------------MGAVFAIMAGFVHWFPLFSGFTLDDTWAKAHFAIMFVGVN------MTFFP--------QHFLGLSG----MPRRYSDYPDAYTTWNTVSSMGSFIS------------------LTAVLIMIFMIWEAFASKREVMSVSYASTNLEWLHG------CPPPYHTFEEPTYVKVK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00395-1", "uniprot_id": "COX1_HUMAN", "id": "P00395-1", "name": "Cytochrome c oxidase subunit 1", "aln": "MFADRWLFSTNHKDIGTLYLLFGAWAGVLGTALSLLIRAELGQPGN--LLGNDHIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSLLLLLASAMVEAGAGTGWTVYPPLAGNYSHPGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHG---------------SNMKWSAAVLWALGFIFLFTVGGLTG-------------IVLANSSLDIVLH----------DTYY-VVAHFH-------YVLS------------------------MGAVFAIMGGFIHWFPLFSGYTLDQTYAKIHFTIMFIGVN------LTFFP--------QHFLGLSG----MPRRYSDYPDAYTTWNILSSVGSFIS------------------LTAVMLMIFMIWEAFASKRKVLMVEEPSMNLEWLYG------CPPPYHTFEEPVYMKS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9MIY8-1", "uniprot_id": "COX1_DANRE", "id": "Q9MIY8-1", "name": "Cytochrome c oxidase subunit 1", "aln": "MTITRWFFSTNHKDIGTLYLVFGAWAGMVGTALSLLIRAELSQPGA--LLGDDQIYNVIVTAHAFVMIFFMVMPILIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSGVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTTINMKPPTISQYQTPLFVWAVLVTAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHVVAYYAGKKEPFGYMGMVWAMMAIGLLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHG---------------GAIKWETPMLWALGFIFLFTVGGLTG-------------IVLANSSLDIVLH----------DTYY-VVAHFH-------YVLS------------------------MGAVFAIMAGFVHWFPLFTGYTLNSVWTKIHFGVMFIGVN------LTFFP--------QHFLGLAG----MPRRYSDYPDAYALWNTVSSIGSLIS------------------LVAVIMFLFILWEAFTAKREVLSVELTATNVEWLHG------CPPPYHTFEEPAFVQIQSN--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P00399-1", "uniprot_id": "COX1_DROME", "id": "P00399-1", "name": "Cytochrome c oxidase subunit 1", "aln": "--SRQWLFSTNHKDIGTLYFIFGAWAGMVGTSLSILIRAELGHPGA--LIGDDQIYNVIVTAHAFIMIFFMVMPIMIGGFGNWLVPLMLGAPDMAFPRMNNMSFWLLPPALSLLLVSSMVENGAGTGWTVYPPLSAGIAHGGASVDLAIFSLHLAGISSILGAVNFITTVINMRSTGISLDRMPLFVWSVVITALLLLLSLPVLAGAITMLLTDRNLNTSFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIISQESGKKETFGSLGMIYAMLAIGLLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAVPTGIKIFSWLATLHG---------------TQLSYSPAILWALGFVFLFTVGGLTG-------------VVLANSSVDIILH----------DTYY-VVAHFH-------YVLS------------------------MGAVFAIMAGFIHWYPLFTGLTLNNKWLKSHFIIMFIGVN------LTFFP--------QHFLGLAG----MPRRYSDYPDAYTTWNIVSTIGSTIS------------------LLGILFFFFIIWESLVSQRQVIYPIQLNSSIEWYQN------TPPAEHSYSELPLLTN-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9ZZX1-1", "uniprot_id": "SCE4_YEAST", "id": "Q9ZZX1-1", "name": "Intron-encoded DNA endonuclease aI5 alpha", "aln": "-MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVVGHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVESGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFGHPEVYILIIPGFGIISHVVSTYS-KKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGLDADTRAYFTSATMIIAIPTGIKIFSWLMNPFSKDKNKNKNKKLIRNYQKMNNNNMMKTYLNNNNMIMMNMYKGNLYDIYPRSNRNYIQPNNINKELVVYGYNLESCVGMPTYTNIVKHMVGIPNNILYIMTGILLTDGWIDYTSKKDLDKKTIMEINCRFRLKQSMIHSEYLMYVFMLLSHYCMSYPKMKIAKVKGKSYNQLEFYTRSLPCFTILRYMFYNGRVKIVPNNLYDLLNYESLAHMIMCDGSFVKGGGLYLNLQSFTTKELIFIMNILKIKFNLNCTLHKSRNKYTIYMRVESVKRLFPMIYKYILPSMRYKFDIMLWQKKYNMIN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*::*** ***..**:::. ::*: **::*::** **. ** * *:.:::**:*..**.:****:*** :******:*:***:**.* ****:**::**:** .: *:.*: ** ************:. :* *.****:**:***:.:**:***:***.* :**:. :: : *****::.:**.*********:..***** ***:**:**: :********:***************:****:***::: : ** ** :.*::** :**:***:**:***: **:*.**************:***:*:**** . .. :. . : *. :: :. .* : * . ::::: ** :* *: *::: :.. * : .::* *: * . : : : : *: : *:. ::: * :*.. * : : : : ** :. : :: : * : :: .*: .:: *. :.:. ", "identical_positions": 216, "similar_positions": 164, "identity": "34.18%" }, { "cls_id": "homologset.agr.SGD:S000007268", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05504-1", "uniprot_id": "ATP6_RAT", "id": "P05504-1", "name": "ATP synthase F(0) complex subunit a", "aln": "-------------------MNENLFASFITPTMMGLPIVVTIIMFPSILFPSSERLISN-------RLHSFQHWLIKLIIKQMMLIHTPKGRT-WALMIVSLIMFIGSTNLLGLLPHTFTPTTQLSMNLSMAIPLWAGAVILGFRHKLKNSLAHFLPQGTPISLIPMLIIIETISLFIQPMALAVRLTANITAGHLLMHLIGGATLVLMDISPPTATITFI---ILLLLTVLEFAVALIQAYVFTLLVSLYLHDNT---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00848-1", "uniprot_id": "ATP6_MOUSE", "id": "P00848-1", "name": "ATP synthase F(0) complex subunit a", "aln": "-------------------MNENLFASFITPTMMGFPIVVAIIMFPSILFPSSKRLINN-------RLHSFQHWLVKLIIKQMMLIHTPKGRT-WTLMIVSLIMFIGSTNLLGLLPHTFTPTTQLSMNLSMAIPLWAGAVITGFRHKLKSSLAHFLPQGTPISLIPMLIIIETISLFIQPMALAVRLTANITAGHLLMHLIGGATLVLMNISPPTATITFI---ILLLLTILEFAVALIQAYVFTLLVSLYLHDNT---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00846-1", "uniprot_id": "ATP6_HUMAN", "id": "P00846-1", "name": "ATP synthase F(0) complex subunit a", "aln": "-------------------MNENLFASFIAPTILGLPAAVLIILFPPLLIPTSKYLINN-------RLITTQQWLIKLTSKQMMTMHNTKGRT-WSLMLVSLIIFIATTNLLGLLPHSFTPTTQLSMNLAMAIPLWAGTVIMGFRSKIKNALAHFLPQGTPTPLIPMLVIIETISLLIQPMALAVRLTANITAGHLLMHLIGSATLAMSTINLPSTLIIFT---ILILLTILEIAVALIQAYVFTLLVSLYLHDNT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00850-1", "uniprot_id": "ATP6_DROME", "id": "P00850-1", "name": "ATP synthase subunit a", "aln": "-------------------MMTNLFSVFDPSAIFNFSLNWLSTFLGLLMIPSIYWLMPS-------RYNIMWNSILLTLHKEFKTLLGPSGHNGSTFIFISLFSLILFNNFMGLFPYIFTSTSHLTLTLSLALPLWLCFMLYGWINHTQHMFAHLVPQGTPAILMPFMVCIETISNIIRPGTLAVRLTANMIAGHLLLTLLGNTGPSMSYI---LVTFLLM---AQIALLVLESAVAMIQSYVFAVLSTLYSSEVN---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00854-1", "uniprot_id": "ATP6_YEAST", "id": "P00854-1", "name": "ATP synthase subunit a", "aln": "MFNLLNTYITSPLDQFEIRTLFGLQSSFIDLSCLNLTTFSLYTIIVLLVITSLYTLTNNNNKIIGSRWLISQEAIYDTIMNMTKGQIGGKNWGLYFPMIFTLFMFIFIANLISMIPYSFALSAHLVFIISLSIVIWLGNTILGLYKHGWVFFSLFVPAGTPLPLVPLLVIIETLSYFARAISLGLRLGSNILAGHLLMVILAGLTFNFMLINLFTLVFGFVPLAMILAIMMLEFAIGIIQGYVWAILTASYLKDAVYLH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* : * : :.:. :: :::.: * . * . : : .. ::.:*: :* *::.::*: *: :::* : ::::: :* : * : :: ::* *** *:*::: ***:* : :. :*.:** :*: *****: ::.. : * : : : : :** *:.:**.**:::* : * : ", "identical_positions": 41, "similar_positions": 82, "identity": "15.83%" }, { "cls_id": "homologset.agr.SGD:S000007270", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P00159-1", "uniprot_id": "CYB_RAT", "id": "P00159-1", "name": "Cytochrome b", "aln": "-MTNIRKSHPLFKIINHSFIDLPAPSNISSWWNFGSLLGVCLMVQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYTFLET--WNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAIVHLLFLHETGSNNPTGLNSDADKIPFHPYYTIKDLLGVFMLLLFLMTLVLFFPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVVALILSILILAFLPFLHTSKQRSLTFRPITQILYWILVANLLILTWIGGQPVEHPFIIIGQLASISYFSIILILMPISGIVEDKMLKWN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00158-1", "uniprot_id": "CYB_MOUSE", "id": "P00158-1", "name": "Cytochrome b", "aln": "-MTNMRKTHPLFKIINHSFIDLPAPSNISSWWNFGSLLGVCLMVQIITGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYTFMET--WNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAIVHLLFLHETGSNNPTGLNSDADKIPFHPYYTIKDILGILIMFLILMTLVLFFPDMLGDPDNYMPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILALMPFLHTSKQRSLMFRPITQILYWILVANLLILTWIGGQPVEHPFIIIGQLASISYFSIILILMPISGIIEDKMLKLYP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00156-1", "uniprot_id": "CYB_HUMAN", "id": "P00156-1", "name": "Cytochrome b", "aln": "-MTPMRKTNPLMKLINHSFIDLPTPSNISAWWNFGSLLGACLILQITTGLFLAMHYSPDASTAFSSIAHITRDVNYGWIIRYLHANGASMFFICLFLHIGRGLYYGSFLYSET--WNIGIILLLATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGYSVDSPTLTRFFTFHFILPFIIAALATLHLLFLHETGSNNPLGITSHSDKITFHPYYTIKDALGLLLFLLSLMTLTLFSPDLLGDPDNYTLANPLNTPPHIKPEWYFLFAYTILRSVPNKLGGVLALLLSILILAMIPILHMSKQQSMMFRPLSQSLYWLLAADLLILTWIGGQPVSYPFTIIGQVASVLYFTTILILMPTISLIENKMLKWA----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18935-1", "uniprot_id": "CYB_DROME", "id": "P18935-1", "name": "Cytochrome b", "aln": "MNKPLRNSHPLFKIANNALVDLPAPINISSWWNFGSLLGLCLIIQILTGLFLAMHYTADINLAFYSVNHICRDVNYGWLLRTLHANGASFFFICIYLHVGRGIYYGSYKFTPT--WLIGVIILFLVMGTAFMGYVLPWGQMSFWGATVITNLLSAIPYLGMDLVQWLWGGFAVDNATLTRFFTFHFILPFIVLAMTMIHLLFLHQTGSNNPIGLNSNIDKIPFHPYFTFKDIVGFIVMIFILISLVLISPNLLGDPDNFIPANPLVTPAHIQPEWYFLFAYAILRSIPNKLGGVIALVLSIAILMILPFYNLSKFRGIQFYPINQVMFWSMLVTVILLTWIGARPVEEPYVLIGQILTVVYFLYYLVN-PLITKWWDNLLN------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00163-1", "uniprot_id": "CYB_YEAST", "id": "P00163-1", "name": "Cytochrome b", "aln": "--MAFRKSNVYLSLVNSYIIDSPQPSSINYWWNMGSLLGLCLVIQIVTGIFMAMHYSSNIELAFSSVEHIMRDVHNGYILRYLHANGASFFFMVMFMHMAKGLYYGSYRSPRVTLWNVGVIIFILTIATAFLGYCCVYGQMSHWGATVITNLFSAIPFVGNDIVSWLWGGFSVSNPTIQRFFALHYLVPFIIAAMVIMHLMALHIHGSSNPLGITGNLDRIPMHSYFIFKDLVTVFLFMLILALFVFYSPNTLGHPDNYIPGNPLVTPASIVPEWYLLPFYAILRSIPDKLLGVITMFAAILVLLVLPFTDRSVVRGNTFKVLSKFFFFIFVFNFVLLGQIGACHVEVPYVLMGQIATFIYFAYFLIIVPVISTIENVLFYIGRVNK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*::: :.: * ::* * * .*. ***:***** **::** **:*:****:.: ** *: ** ***: *:::* :******:**: :::*:.:*:****: . * :*::::: .:.***:** :****.*********:****::* :*.*:***::*...*: ***::*:::***: *:. :**: ** **.** *:... *:*.:*.*: :** : .::::: * :.: *: **.***: .*** **. * ****:* *:****:*:** **:::. :* :* .:*: . * :. * :.: ::: : .::* **. *. *: ::**: :. ** *: * : :: ", "identical_positions": 148, "similar_positions": 134, "identity": "38.24%" }, { "cls_id": "homologset.agr.SGD:S000007271", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P00159-1", "uniprot_id": "CYB_RAT", "id": "P00159-1", "name": "Cytochrome b", "aln": "-MTNIRKSHPLFKIINHSFIDLPAPSNISSWWNFGSLLGVCLMVQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYT--FLETWNIGIILLFAVMATAFMGYVLPWGQMSFWG----ATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFI-LPFIIAALAIVHLLFLHETGSNNPTG------------------------------LNSDADKIPFHPYYTIKDLLGVFMLLLFLMTLVLFFPDLLGDPDNYTPAN--PLNTPPHIKPEWYFLFAY--AILRSIPNKLG---GVVALILSILILAFLPFLHTSKQRSLTFRPITQILYWILVANLLILTWIGGQPVEHPFIIIGQLASISYFSIILILMPISGIVEDKMLKWN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00158-1", "uniprot_id": "CYB_MOUSE", "id": "P00158-1", "name": "Cytochrome b", "aln": "-MTNMRKTHPLFKIINHSFIDLPAPSNISSWWNFGSLLGVCLMVQIITGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYT--FMETWNIGVLLLFAVMATAFMGYVLPWGQMSFWG----ATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFI-LPFIIAALAIVHLLFLHETGSNNPTG------------------------------LNSDADKIPFHPYYTIKDILGILIMFLILMTLVLFFPDMLGDPDNYMPAN--PLNTPPHIKPEWYFLFAY--AILRSIPNKLG---GVLALILSILILALMPFLHTSKQRSLMFRPITQILYWILVANLLILTWIGGQPVEHPFIIIGQLASISYFSIILILMPISGIIEDKMLKLYP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00156-1", "uniprot_id": "CYB_HUMAN", "id": "P00156-1", "name": "Cytochrome b", "aln": "-MTPMRKTNPLMKLINHSFIDLPTPSNISAWWNFGSLLGACLILQITTGLFLAMHYSPDASTAFSSIAHITRDVNYGWIIRYLHANGASMFFICLFLHIGRGLYYGSFL--YSETWNIGIILLLATMATAFMGYVLPWGQMSFWG----ATVITNLLSAIPYIGTDLVQWIWGGYSVDSPTLTRFFTFHFI-LPFIIAALATLHLLFLHETGSNNPLG------------------------------ITSHSDKITFHPYYTIKDALGLLLFLLSLMTLTLFSPDLLGDPDNYTLAN--PLNTPPHIKPEWYFLFAY--TILRSVPNKLG---GVLALLLSILILAMIPILHMSKQQSMMFRPLSQSLYWLLAADLLILTWIGGQPVSYPFTIIGQVASVLYFTTILILMPTISLIENKMLKWA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18935-1", "uniprot_id": "CYB_DROME", "id": "P18935-1", "name": "Cytochrome b", "aln": "MNKPLRNSHPLFKIANNALVDLPAPINISSWWNFGSLLGLCLIIQILTGLFLAMHYTADINLAFYSVNHICRDVNYGWLLRTLHANGASFFFICIYLHVGRGIYYGSYK--FTPTWLIGVIILFLVMGTAFMGYVLPWGQMSFWG----ATVITNLLSAIPYLGMDLVQWLWGGFAVDNATLTRFFTFHFI-LPFIVLAMTMIHLLFLHQTGSNNPIG------------------------------LNSNIDKIPFHPYFTFKDIVGFIVMIFILISLVLISPNLLGDPDNFIPAN--PLVTPAHIQPEWYFLFAY--AILRSIPNKLG---GVIALVLSIAILMILPFYNLSKFRGIQFYPINQVMFWSMLVTVILLTWIGARPVEEPYVLIGQILTVVYFLYYLVN-PLITKWWDNLLN---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P03873-1", "uniprot_id": "MBI2_YEAST", "id": "P03873-1", "name": "Cytochrome b mRNA maturase bI2", "aln": "--MAFRKSNVYLSLVNSYIIDSPQPSSINYWWNMGSLLGLCLVIQIVTGIFMAMHYSSNIELAFSSVEHIMRDVHNGYILRYLHANGASFFFMVMFMHMAKGLYYGSYRSPRVTLWNVGVIIFILTIATAFLGYCCVYGQMSHWGNMNIASNMFNMMKTIYMMMLMLLIYIFYTIMMRQMMKTKEYTMLIKSMDYINKNKYMINLNMTNKKDMNNNIGPLNMNILSIIYGSMLGDGHAEKRKGGKGTRIVFQQEYCNINYLYYLHSLLANLGYCNTNLPLIKTRLGKKGKIRQYLKFNTWTYDSFNMIYSEWYIKNMSGKGNIKVIPKSLDNYLTPLALAIWIMDDGCKLGKGLKFTTNCFSYKDVQYLTYLLHNKYNIKSTITKGNKENTQFVIYVWKESMPILTKIVSPYIIPSMKYKLGNYL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*::: :.: * ::* * * .*. ***:***** **::** **:*:****:.: ** *: ** ***: *:::* :******:**: :::*:.:*:****: * :*::::: .:.***:** :****.** *: : *::.:* : *: ::: : . *: ::: : : :* ::* : ::.. ** * : . : :: : ::. :. : :.* . *. :: * . : * .***: :: :*:.*. :** : * . . * : : : : : * . . :* : :: :: : ", "identical_positions": 87, "similar_positions": 120, "identity": "20.42%" } ]